# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Plectin PF00681.20 RUS68367.1 - 8.2e-05 22.4 3.3 39 4.2 0.0 6.5 1 1 6 7 7 7 1 Plectin repeat DUF5070 PF16802.5 RUS68367.1 - 0.086 12.8 8.0 8.2 6.4 1.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5070) CxC2 PF18803.1 RUS68367.1 - 6.8 6.9 21.6 7.7 6.7 3.0 3.3 1 1 4 5 5 5 0 CxC2 like cysteine cluster associated with KDZ transposases Transglut_i_TM PF14400.6 RUS68369.1 - 0.0073 16.4 0.0 17 5.5 0.0 3.7 4 0 0 4 4 4 2 Inactive transglutaminase fused to 7 transmembrane helices Porin_2 PF02530.14 RUS68369.1 - 0.075 12.3 1.4 12 5.0 0.1 3.2 1 1 2 3 3 3 0 Porin subfamily DUF4964 PF16334.5 RUS68370.1 - 1.6 8.3 13.0 1.8 8.2 0.8 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4964) RPE65 PF03055.15 RUS68372.1 - 8.6e-30 104.3 0.0 1e-29 104.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein zf-C2H2_4 PF13894.6 RUS68375.1 - 1e-14 53.9 26.8 0.0017 19.0 0.4 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS68375.1 - 2e-13 50.0 31.2 0.0012 19.1 3.6 5.4 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS68375.1 - 2.9e-11 43.3 21.9 0.011 16.0 0.1 5.3 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS68375.1 - 8.9e-11 41.5 19.6 0.017 15.1 0.6 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 RUS68375.1 - 0.0002 21.7 24.0 0.044 14.2 0.2 5.6 5 1 0 5 5 5 1 Zinc-finger of C2H2 type C1_1 PF00130.22 RUS68375.1 - 0.0026 17.6 16.3 0.017 15.0 2.0 3.3 2 1 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 RUS68375.1 - 0.0027 17.8 12.5 0.052 13.7 0.1 4.7 4 1 1 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 RUS68375.1 - 0.0034 17.7 27.5 1.4 9.5 0.1 6.4 5 1 1 6 6 6 1 Zinc-finger double domain Desulfoferrod_N PF06397.12 RUS68375.1 - 0.0068 16.0 12.9 0.43 10.2 0.0 4.4 5 0 0 5 5 5 2 Desulfoferrodoxin, N-terminal domain Cript PF10235.9 RUS68375.1 - 0.012 16.2 15.7 0.014 16.0 1.9 3.2 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT Zn-C2H2_12 PF18112.1 RUS68375.1 - 0.021 15.3 12.3 0.77 10.3 0.0 4.7 5 1 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain Baculo_IE-1 PF05290.11 RUS68375.1 - 0.026 14.5 9.7 0.44 10.5 1.5 2.4 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Elf1 PF05129.13 RUS68375.1 - 0.031 14.3 2.0 0.031 14.3 2.0 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 RUS68375.1 - 0.043 13.9 16.8 0.67 10.1 1.9 4.1 3 2 1 4 4 4 0 Zinc ribbon domain Vps36-NZF-N PF16988.5 RUS68375.1 - 0.047 13.1 11.0 0.11 12.0 0.5 3.7 1 1 2 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.7 RUS68375.1 - 0.062 13.6 21.6 3.9 7.9 9.1 3.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 RUS68375.1 - 0.081 12.8 11.5 2 8.3 0.2 4.4 2 1 3 5 5 4 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 RUS68375.1 - 0.087 12.4 17.5 1.1 8.9 0.2 4.8 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Actin_micro PF17003.5 RUS68375.1 - 0.092 11.9 17.7 0.12 11.5 8.0 3.0 1 1 2 3 3 3 0 Putative actin-like family Cu2_monooxygen PF01082.20 RUS68375.1 - 0.11 12.7 8.5 0.26 11.5 1.3 2.2 1 1 1 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain ADK_lid PF05191.14 RUS68375.1 - 0.11 12.5 13.9 1 9.4 1.7 4.2 2 2 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 RUS68375.1 - 0.12 12.2 16.3 1.4 8.8 0.7 4.9 3 1 2 5 5 5 0 zinc-finger of acetyl-transferase ESCO zf-FPG_IleRS PF06827.14 RUS68375.1 - 0.14 12.0 10.3 3.6 7.5 0.7 4.4 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zf_ZIC PF18366.1 RUS68375.1 - 0.24 11.5 8.6 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain FYVE PF01363.21 RUS68375.1 - 0.25 11.5 23.0 11 6.2 18.8 3.8 1 1 1 2 2 2 0 FYVE zinc finger FlhC PF05280.11 RUS68375.1 - 0.33 10.7 10.0 0.31 10.7 1.9 2.2 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) Prok-RING_1 PF14446.6 RUS68375.1 - 0.41 10.6 17.3 18 5.4 0.1 4.9 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 RAG1_imp_bd PF12560.8 RUS68375.1 - 0.76 9.3 12.2 1.1 8.7 0.2 3.5 1 1 4 5 5 5 0 RAG1 importin binding zinc_ribbon_15 PF17032.5 RUS68375.1 - 0.9 10.3 14.0 2.2 9.1 3.5 2.7 1 1 0 2 2 2 0 zinc-ribbon family DUF2310 PF10071.9 RUS68375.1 - 0.93 8.7 5.7 1.7 7.9 0.6 2.2 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DUF629 PF04780.12 RUS68375.1 - 1.3 7.5 16.3 0.43 9.1 1.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 RUS68375.1 - 1.8 8.4 23.2 2.9 7.7 1.8 4.7 4 1 1 5 5 5 0 zinc-finger C2H2-type zf-C2HC5 PF06221.13 RUS68375.1 - 3.6 7.6 17.5 0.61 10.1 1.5 4.4 2 1 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-HIT PF04438.16 RUS68375.1 - 4.5 7.2 0.0 4.5 7.2 0.0 5.1 5 1 1 6 6 6 0 HIT zinc finger Zn_ribbon_2 PF12674.7 RUS68375.1 - 5.5 7.7 9.0 1 10.1 0.4 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain XPA_N PF01286.18 RUS68375.1 - 6.7 6.8 20.8 9.7 6.3 0.1 5.1 5 0 0 5 5 5 0 XPA protein N-terminal DUF3268 PF11672.8 RUS68375.1 - 7.4 6.9 10.4 1.5 9.1 1.6 2.6 2 1 1 3 3 3 0 zinc-finger-containing domain zf-C2H2 PF00096.26 RUS68376.1 - 2.4e-08 34.0 6.8 0.00083 19.7 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS68376.1 - 2.1e-07 31.2 4.2 0.0024 18.6 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS68376.1 - 0.00014 22.1 1.3 0.32 11.3 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3 PF13878.6 RUS68376.1 - 0.0042 16.9 2.6 0.2 11.5 0.1 2.5 2 1 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf-Di19 PF05605.12 RUS68376.1 - 0.0058 16.9 1.5 1 9.7 0.2 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 RUS68376.1 - 0.013 15.4 2.4 0.043 13.7 0.5 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 RUS68376.1 - 0.013 16.2 0.2 2.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats OrfB_Zn_ribbon PF07282.11 RUS68376.1 - 0.015 15.2 0.7 4.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.6 RUS68376.1 - 0.015 15.2 3.3 0.12 12.3 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RCDG1 PF15725.5 RUS68376.1 - 0.03 14.7 4.3 0.042 14.3 4.3 1.2 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein ADK_lid PF05191.14 RUS68376.1 - 0.039 13.9 0.1 4.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid XAF1_C PF18608.1 RUS68376.1 - 0.04 13.5 0.7 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain zf-C2H2_6 PF13912.6 RUS68376.1 - 0.066 13.2 2.5 0.12 12.4 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Lar_restr_allev PF14354.6 RUS68376.1 - 0.069 13.5 0.3 1 9.8 0.1 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf_UBZ PF18439.1 RUS68376.1 - 0.075 12.6 0.3 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 RUS68376.1 - 0.11 12.4 2.0 8.5 6.4 0.3 2.2 2 0 0 2 2 2 0 PHD-finger zf-UBP PF02148.19 RUS68376.1 - 0.12 12.8 2.2 0.84 10.0 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.6 RUS68376.1 - 0.12 11.8 2.5 4.5 6.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PHD_2 PF13831.6 RUS68376.1 - 0.17 11.5 1.9 6 6.5 0.2 2.3 2 0 0 2 2 2 0 PHD-finger zf-RanBP PF00641.18 RUS68376.1 - 0.54 9.6 3.7 3.8 6.9 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf_C2H2_ZHX PF18387.1 RUS68376.1 - 0.82 9.4 3.4 14 5.4 0.3 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Type_III_YscX PF09474.10 RUS68377.1 - 0.026 14.8 1.5 4.4 7.6 0.1 2.4 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) Herpes_BLLF1 PF05109.13 RUS68377.1 - 0.059 11.4 7.5 0.067 11.2 7.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Hep_core_N PF08290.11 RUS68377.1 - 0.19 11.7 0.1 0.19 11.7 0.1 5.2 2 1 3 6 6 6 0 Hepatitis core protein, putative zinc finger Amb_V_allergen PF03913.13 RUS68379.1 - 0.0026 17.6 29.9 2.2 8.3 0.3 6.4 1 1 6 7 7 7 5 Amb V Allergen Hormone_5 PF00184.17 RUS68379.1 - 0.035 14.9 12.3 7.5 7.5 0.5 3.4 2 1 1 3 3 3 0 Neurohypophysial hormones, C-terminal Domain DNA_gyraseA_C PF03989.13 RUS68379.1 - 0.069 12.6 5.0 1.4e+02 2.1 0.0 5.3 6 0 0 6 6 6 0 DNA gyrase C-terminal domain, beta-propeller GMC_oxred_N PF00732.19 RUS68380.1 - 2e-28 99.6 0.0 2.2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 RUS68380.1 - 5.9e-06 26.4 0.2 3.5e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RUS68380.1 - 0.0036 16.4 0.2 0.0047 16.0 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FPV060 PF17614.2 RUS68382.1 - 0.00032 20.2 28.1 0.023 14.1 6.3 3.1 1 1 2 3 3 3 3 Viral CC-type chemokine RRM_1 PF00076.22 RUS68383.1 - 6.8e-10 38.6 0.1 8.6e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS68383.1 - 0.00027 20.9 0.1 0.00028 20.9 0.1 1.1 1 0 0 1 1 1 1 RNA binding motif DUF2977 PF11192.8 RUS68383.1 - 0.033 14.3 0.1 0.074 13.2 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2977) SMC_N PF02463.19 RUS68384.1 - 6e-05 22.6 0.1 6.2e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 RUS68384.1 - 0.00029 21.3 0.2 0.00077 20.0 0.1 1.7 2 0 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 RUS68384.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TB PF00683.17 RUS68385.1 - 0.091 12.5 17.2 25 4.7 0.3 5.0 1 1 7 8 8 8 0 TB domain FAM47 PF14642.6 RUS68385.1 - 0.099 12.2 6.4 2 7.9 1.5 2.2 1 1 1 2 2 2 0 FAM47 family CC PF04942.14 RUS68385.1 - 0.24 11.6 35.7 4.9 7.4 1.2 5.7 1 1 7 8 8 8 0 CC domain Fer4_3 PF12798.7 RUS68385.1 - 0.78 10.8 17.9 7.5e+02 1.5 0.0 8.6 9 0 0 9 9 9 0 4Fe-4S binding domain PSGP PF07276.11 RUS68385.1 - 0.96 10.0 25.5 3.9e+02 1.8 0.1 9.7 10 0 0 10 10 10 0 Apopolysialoglycoprotein (PSGP) BRCT_3 PF18428.1 RUS68386.1 - 0.18 11.9 15.0 92 3.2 0.0 6.6 2 2 4 6 6 6 0 BRCA1 C Terminus (BRCT) domain DUF5543 PF17697.1 RUS68386.1 - 4.1 7.7 17.1 49 4.2 1.3 5.8 1 1 6 7 7 7 0 Family of unknown function (DUF5543) DUF4573 PF15140.6 RUS68387.1 - 0.00038 20.3 6.6 0.0005 19.9 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) TSC21 PF15217.6 RUS68390.1 - 0.42 10.5 4.9 0.9 9.5 0.0 2.8 1 1 3 4 4 4 0 TSC21 family Ank_4 PF13637.6 RUS68393.1 - 1.9e-12 47.4 0.1 4.9e-09 36.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS68393.1 - 5.2e-12 45.7 0.1 6.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS68393.1 - 1.9e-11 43.1 0.0 2e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RUS68393.1 - 4.5e-11 43.2 0.0 6.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS68393.1 - 6.3e-10 39.0 0.6 0.00036 20.9 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RUS68394.1 - 7.1e-06 26.5 0.0 2.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS68394.1 - 6.6e-05 23.2 1.4 1 10.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS68394.1 - 8.7e-05 23.0 0.0 0.037 14.6 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS68394.1 - 0.00025 21.3 0.1 0.14 12.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS68394.1 - 0.0013 19.0 0.2 4.3 8.2 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat DSPc PF00782.20 RUS68395.1 - 4.1e-33 114.0 0.0 5.5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS68395.1 - 1.4e-06 28.0 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thymosin PF01290.20 RUS68395.1 - 0.0065 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Thymosin beta-4 family Init_tRNA_PT PF04179.12 RUS68395.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain SAYSvFN PF10260.9 RUS68396.1 - 2.1e-05 24.4 0.2 66 3.5 0.0 5.8 1 1 8 9 9 9 6 Uncharacterized conserved domain (SAYSvFN) DUF1667 PF07892.11 RUS68396.1 - 0.00023 21.2 0.0 52 4.0 0.0 4.8 1 1 7 8 8 8 4 Protein of unknown function (DUF1667) V-set PF07686.17 RUS68397.1 - 0.00059 20.0 0.0 0.00074 19.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 RUS68397.1 - 0.03 14.9 0.0 0.053 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Polysacc_deac_2 PF04748.13 RUS68397.1 - 0.061 12.5 0.0 0.066 12.4 0.0 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase HTH_32 PF13565.6 RUS68398.1 - 0.00015 22.3 0.1 0.00033 21.2 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS68398.1 - 0.00072 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 RUS68398.1 - 0.00077 19.7 0.2 0.0015 18.7 0.2 1.5 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS68398.1 - 0.0029 17.6 0.1 0.0051 16.8 0.1 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF977) PCI PF01399.27 RUS68398.1 - 0.015 15.8 0.0 0.023 15.2 0.0 1.3 1 1 0 1 1 1 0 PCI domain HTH_24 PF13412.6 RUS68398.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 RUS68398.1 - 0.019 14.8 1.6 2.3 8.1 0.0 2.7 2 1 0 2 2 2 0 Homeodomain-like domain DUF4817 PF16087.5 RUS68398.1 - 0.023 14.5 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS68398.1 - 0.026 14.9 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS68398.1 - 0.044 13.2 0.1 0.078 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 RUS68398.1 - 0.069 13.3 0.0 9.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 RUS68398.1 - 0.074 13.1 0.0 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_25 PF13413.6 RUS68398.1 - 0.17 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Serpin PF00079.20 RUS68399.1 - 4.2e-30 105.3 0.1 4.5e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SpoIIE PF07228.12 RUS68399.1 - 0.079 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Pyridoxal_deC PF00282.19 RUS68401.1 - 4.5e-18 65.1 0.0 4.8e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain TatD_DNase PF01026.21 RUS68405.1 - 5.2e-17 62.1 0.0 5.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NifT PF06988.11 RUS68406.1 - 9.4e-08 31.7 0.4 13 5.6 0.0 6.4 2 2 5 7 7 7 1 NifT/FixU protein AMPK1_CBM PF16561.5 RUS68406.1 - 0.00016 21.9 3.8 3.4 8.0 0.1 5.0 1 1 4 5 5 5 2 Glycogen recognition site of AMP-activated protein kinase SprB PF13573.6 RUS68406.1 - 0.0019 17.9 7.3 36 4.2 0.0 6.4 6 1 1 7 7 7 0 SprB repeat DUF4835 PF16119.5 RUS68406.1 - 0.012 14.7 0.4 2.4 7.2 0.1 3.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4835) DUF2173 PF09941.9 RUS68406.1 - 0.8 10.0 3.9 37 4.7 0.1 3.8 2 2 3 6 6 6 0 Uncharacterized conserved protein (DUF2173) DHH PF01368.20 RUS68406.1 - 1.6 9.0 4.4 15 5.9 0.4 3.1 2 1 0 2 2 2 0 DHH family ANAPC10 PF03256.16 RUS68408.1 - 0.0008 19.1 0.1 1.1 8.9 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, subunit 10 (APC10) Plasmodium_HRP PF05403.11 RUS68408.1 - 0.0012 18.7 0.1 0.0061 16.4 0.1 1.9 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) QLQ PF08880.11 RUS68408.1 - 0.019 14.7 0.3 33 4.3 0.0 4.5 3 2 2 5 5 5 0 QLQ PcF PF09461.10 RUS68408.1 - 0.024 15.0 3.4 96 3.5 0.0 5.0 2 2 4 7 7 7 0 Phytotoxin PcF protein RBD PF02196.15 RUS68408.1 - 0.11 12.6 1.3 15 5.8 0.0 3.1 1 1 2 3 3 3 0 Raf-like Ras-binding domain Limkain-b1 PF11608.8 RUS68408.1 - 7.7 6.7 10.5 1.1e+02 3.0 0.1 4.8 2 2 3 6 6 6 0 Limkain b1 GalKase_gal_bdg PF10509.9 RUS68409.1 - 0.12 11.9 0.0 1.1e+02 2.4 0.0 4.2 5 0 0 5 5 5 0 Galactokinase galactose-binding signature Gmad1 PF10647.9 RUS68409.1 - 0.15 11.8 4.9 33 4.1 0.0 4.7 2 2 4 6 6 6 0 Lipoprotein LpqB beta-propeller domain UBA_5 PF16577.5 RUS68409.1 - 0.46 10.7 4.6 27 5.0 0.0 4.2 4 0 0 4 4 4 0 UBA domain MATalpha_HMGbox PF04769.12 RUS68409.1 - 2.5 7.4 5.4 52 3.1 0.1 2.9 1 1 2 3 3 3 0 Mating-type protein MAT alpha 1 HMG-box CSN5_C PF18323.1 RUS68411.1 - 1.7 9.6 4.6 0.5 11.3 0.6 2.0 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain MMtag PF10159.9 RUS68411.1 - 2.5 8.5 5.8 0.38 11.1 0.6 2.0 2 0 0 2 2 2 0 Multiple myeloma tumor-associated RRM_3 PF08777.11 RUS68411.1 - 2.6 8.1 9.3 0.34 11.0 2.1 2.6 2 2 1 3 3 3 0 RNA binding motif MutS_IV PF05190.18 RUS68413.1 - 0.016 15.5 0.1 0.062 13.7 0.0 2.0 2 0 0 2 2 2 0 MutS family domain IV GP46 PF07409.12 RUS68413.1 - 0.13 12.0 1.8 0.24 11.2 1.2 1.9 1 1 1 2 2 2 0 Phage protein GP46 Ank_4 PF13637.6 RUS68414.1 - 2.1e-33 114.3 2.8 8.7e-12 45.3 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS68414.1 - 6.1e-30 103.6 1.5 1.2e-10 41.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS68414.1 - 3.5e-26 90.9 13.6 1.5e-09 37.9 0.2 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS68414.1 - 6.2e-22 77.0 1.5 0.0017 18.7 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RUS68414.1 - 2.1e-21 73.7 2.2 0.0065 16.9 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat DUF2773 PF10971.8 RUS68414.1 - 0.0035 17.4 0.0 3 8.0 0.0 2.8 1 1 3 4 4 4 2 Protein of unknown function (DUF2773) YppF PF14178.6 RUS68414.1 - 0.11 12.3 0.1 14 5.6 0.0 2.8 3 0 0 3 3 3 0 YppF-like protein TMEM247 PF15444.6 RUS68415.1 - 0.32 11.0 2.2 0.45 10.5 1.7 1.5 1 1 0 1 1 1 0 Transmembrane protein 247 P4Ha_N PF08336.11 RUS68416.1 - 2.1e-08 34.2 0.1 2.5e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RCC_reductase PF06405.11 RUS68418.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) TPR_1 PF00515.28 RUS68419.1 - 2.4e-10 39.8 0.2 0.0012 18.5 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS68419.1 - 1.5e-09 37.2 0.2 0.014 15.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS68419.1 - 2.3e-09 36.7 0.5 0.0039 17.3 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS68419.1 - 2e-06 27.8 0.1 3.4e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS68419.1 - 2.6e-06 27.8 0.4 4.4e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS68419.1 - 2.6e-05 23.8 0.0 1.4 8.6 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 RUS68419.1 - 0.0002 21.9 0.1 0.64 11.0 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS68419.1 - 0.00023 21.3 0.1 0.0017 18.6 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS68419.1 - 0.00045 20.2 0.8 0.0097 16.0 0.1 2.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RUS68419.1 - 0.0081 16.6 0.1 0.023 15.2 0.1 1.8 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_16 PF13432.6 RUS68419.1 - 0.0091 16.6 0.1 0.089 13.5 0.1 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS68419.1 - 0.011 15.8 0.4 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS68419.1 - 0.015 15.6 0.8 0.056 13.7 0.2 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS68419.1 - 0.055 13.7 0.1 0.078 13.2 0.1 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RUS68420.1 - 6.8e-10 38.3 0.3 0.0019 18.0 0.6 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS68420.1 - 3.5e-09 36.1 0.2 0.019 15.0 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS68420.1 - 8.1e-09 35.0 0.8 0.0069 16.5 0.0 3.6 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS68420.1 - 3.7e-06 27.0 0.1 7.4e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS68420.1 - 4.9e-06 27.0 0.1 9.6e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RUS68420.1 - 6.6e-05 23.4 0.1 0.00014 22.3 0.1 1.7 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_11 PF13414.6 RUS68420.1 - 9.4e-05 22.0 0.0 2.2 8.0 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 RUS68420.1 - 0.00018 22.0 0.1 0.46 11.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS68420.1 - 0.00052 20.2 0.2 0.0031 17.8 0.0 2.4 3 1 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS68420.1 - 0.00071 19.6 0.1 0.015 15.3 0.1 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 RUS68420.1 - 0.024 14.9 0.6 0.078 13.3 0.2 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS68420.1 - 0.037 14.7 0.1 0.11 13.1 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS68420.1 - 0.037 14.0 0.5 18 5.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS68420.1 - 0.05 13.8 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 RUS68420.1 - 0.092 11.7 0.1 0.26 10.3 0.1 1.5 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Histone PF00125.24 RUS68421.1 - 7.8e-35 120.1 2.0 9.5e-35 119.8 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RUS68421.1 - 3.6e-05 23.8 0.7 6.2e-05 23.1 0.3 1.5 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RUS68421.1 - 0.00045 20.5 0.1 0.00062 20.1 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RUS68421.1 - 0.0083 16.4 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RUS68421.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Spt4 PF06093.13 RUS68422.1 - 1.5e-10 41.0 0.1 1.8e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RVT_1 PF00078.27 RUS68423.1 - 3.2e-09 36.6 0.1 4.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3225 PF11533.8 RUS68423.1 - 0.12 12.1 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) RNase_H PF00075.24 RUS68425.1 - 8.8e-18 64.9 0.4 3.3e-17 63.0 0.4 1.9 1 1 0 1 1 1 1 RNase H COPIIcoated_ERV PF07970.12 RUS68425.1 - 2.7e-11 43.7 0.3 5.2e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter RVT_3 PF13456.6 RUS68425.1 - 7.6e-05 22.5 0.1 0.00018 21.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Histone PF00125.24 RUS68426.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68426.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68426.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68426.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68426.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Collagen PF01391.18 RUS68427.1 - 0.0001 22.0 8.6 0.068 12.9 2.8 3.3 2 2 0 2 2 2 2 Collagen triple helix repeat (20 copies) phage_tail_N PF08400.10 RUS68427.1 - 1.8 8.6 14.1 24 4.9 2.1 4.9 1 1 3 4 4 4 0 Prophage tail fibre N-terminal PLAC9 PF15205.6 RUS68428.1 - 0.18 12.2 0.2 2.4e+02 2.2 0.0 5.0 4 2 2 6 6 6 0 Placenta-specific protein 9 FAR1 PF03101.15 RUS68430.1 - 0.0002 22.0 0.8 0.00028 21.5 0.6 1.4 1 1 0 1 1 1 1 FAR1 DNA-binding domain DUF839 PF05787.13 RUS68430.1 - 0.13 11.3 0.0 8.4 5.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF839) Neur_chan_LBD PF02931.23 RUS68431.1 - 4.3e-11 42.7 0.1 6.3e-11 42.1 0.1 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Histone PF00125.24 RUS68432.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68432.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68432.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68432.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68432.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Fibrinogen_C PF00147.18 RUS68434.1 - 3.8e-55 187.1 7.3 3.8e-55 187.1 7.3 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lipoprotein_15 PF03640.15 RUS68434.1 - 0.16 11.6 2.4 0.32 10.6 2.4 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function DNA_pol_B PF00136.21 RUS68436.1 - 1.7e-64 218.3 0.2 1.9e-64 218.1 0.2 1.0 1 0 0 1 1 1 1 DNA polymerase family B Histone PF00125.24 RUS68437.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68437.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68437.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68437.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68437.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 RUS68438.1 - 1.9e-21 75.5 0.9 2.7e-21 75.0 0.9 1.2 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RUS68438.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 RUS68439.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68439.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68439.1 - 0.00039 20.9 0.0 0.00068 20.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68439.1 - 0.0045 17.0 0.6 0.0051 16.9 0.6 1.2 1 0 0 1 1 1 1 YscO-like protein ketoacyl-synt PF00109.26 RUS68442.1 - 1.3e-39 136.3 0.0 5.8e-39 134.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS68442.1 - 2.2e-27 95.4 0.1 3.7e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 RUS68442.1 - 0.00026 20.4 0.9 0.00038 19.9 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain RVT_1 PF00078.27 RUS68444.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPE65 PF03055.15 RUS68447.1 - 2.6e-21 76.4 0.0 3e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RNase_H PF00075.24 RUS68448.1 - 1.3e-13 51.3 2.0 1.6e-13 51.1 1.3 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS68448.1 - 0.0014 18.4 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like HATPase_c_5 PF14501.6 RUS68448.1 - 0.011 15.6 4.6 0.066 13.1 4.6 2.1 1 1 0 1 1 1 0 GHKL domain RVT_1 PF00078.27 RUS68448.1 - 0.015 14.8 0.3 0.034 13.7 0.2 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pga1 PF10333.9 RUS68448.1 - 0.089 12.6 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Spc7_C2 PF15577.6 RUS68448.1 - 0.092 12.8 0.1 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Spc7_C2 RGCC PF15151.6 RUS68450.1 - 0.24 11.6 0.0 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family adh_short PF00106.25 RUS68452.1 - 1.7e-15 57.0 0.1 2.2e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS68452.1 - 1.7e-11 44.1 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS68452.1 - 0.00062 19.7 0.0 0.00069 19.6 0.0 1.1 1 0 0 1 1 1 1 KR domain CdAMP_rec PF06153.11 RUS68452.1 - 0.047 13.9 0.1 0.058 13.6 0.1 1.1 1 0 0 1 1 1 0 Cyclic-di-AMP receptor Histone PF00125.24 RUS68453.1 - 2.4e-52 176.8 3.4 5.9e-43 146.4 1.3 2.0 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RUS68453.1 - 0.00022 21.8 1.0 0.00027 21.5 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 RUS68453.1 - 0.0023 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4840 PF16128.5 RUS68453.1 - 0.0049 16.9 0.0 2.7 8.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4840) DUF746 PF05344.11 RUS68453.1 - 0.008 16.0 0.3 2 8.3 0.1 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF746) Alk_phosphatase PF00245.20 RUS68453.1 - 0.026 13.5 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase RasGAP_C PF03836.15 RUS68453.1 - 0.14 12.3 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 RasGAP C-terminus Nic96 PF04097.14 RUS68454.1 - 7.6e-12 44.5 0.4 1.4e-11 43.6 0.4 1.4 1 0 0 1 1 1 1 Nup93/Nic96 DUF5309 PF17236.2 RUS68454.1 - 0.23 10.8 3.2 0.12 11.8 0.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5309) Vfa1 PF08432.10 RUS68454.1 - 0.25 11.6 8.7 0.38 11.1 8.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 L_lactis_ph-MCP PF06673.11 RUS68454.1 - 2.2 7.2 9.2 3 6.8 9.2 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF5401 PF17380.2 RUS68454.1 - 5.1 5.1 20.1 5.9 4.8 20.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) APG6_N PF17675.1 RUS68454.1 - 5.6 7.5 27.2 8.9 6.8 27.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3730 PF12530.8 RUS68455.1 - 0.1 12.1 2.7 6.9 6.2 2.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) RTP PF02334.16 RUS68455.1 - 0.29 11.8 1.3 40 4.9 0.0 2.7 1 1 2 3 3 3 0 Replication terminator protein RepA1_leader PF08048.12 RUS68455.1 - 0.73 10.1 21.3 56 4.1 0.1 6.6 2 2 3 6 6 6 0 Tap RepA1 leader peptide DB PF01682.19 RUS68456.1 - 2.1 8.7 23.7 31 4.9 9.1 2.3 1 1 1 2 2 2 0 DB module Colipase-like PF15083.6 RUS68456.1 - 5.6 7.2 15.4 4.2 7.5 11.4 2.0 1 1 1 2 2 2 0 Colipase-like Parathyroid PF01279.17 RUS68456.1 - 7.6 7.2 11.0 2.1e+02 2.5 11.0 2.2 1 1 0 1 1 1 0 Parathyroid hormone family Aminotran_3 PF00202.21 RUS68457.1 - 4.3e-43 147.5 0.0 4.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF3389 PF11869.8 RUS68458.1 - 0.026 14.7 0.1 15 5.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) SWM_repeat PF13753.6 RUS68458.1 - 0.12 12.5 4.5 9.8 6.4 0.1 3.2 3 0 0 3 3 3 0 Putative flagellar system-associated repeat V_ATPase_prox PF18274.1 RUS68458.1 - 6.4 6.8 9.9 48 4.0 0.2 4.0 3 1 1 4 4 4 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Pkinase PF00069.25 RUS68459.1 - 2.2e-23 83.0 0.0 4.1e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS68459.1 - 1.5e-13 50.7 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS68459.1 - 0.0065 15.8 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS68459.1 - 0.0073 15.7 0.1 0.0096 15.3 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS68459.1 - 0.028 13.2 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RUS68459.1 - 0.06 13.3 0.2 0.093 12.6 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mo-co_dimer PF03404.16 RUS68460.1 - 7e-35 120.0 0.5 1.3e-34 119.2 0.4 1.4 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 RUS68460.1 - 0.016 15.1 0.1 0.077 13.0 0.1 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat RT_RNaseH_2 PF17919.1 RUS68461.1 - 1.8e-27 95.3 0.0 4.1e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68461.1 - 6.7e-24 84.2 0.0 1.8e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68461.1 - 6.1e-14 52.1 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS68461.1 - 0.0002 21.8 0.0 0.00054 20.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SprT-like PF10263.9 RUS68461.1 - 0.06 13.2 0.2 0.23 11.3 0.2 2.0 1 0 0 1 1 1 0 SprT-like family Asp_protease_2 PF13650.6 RUS68461.1 - 0.11 13.1 0.0 0.3 11.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease SOAR PF16533.5 RUS68461.1 - 0.76 9.8 4.6 1.8 8.6 0.0 3.1 3 0 0 3 3 3 0 STIM1 Orai1-activating region UPF0730 PF15827.5 RUS68462.1 - 9.8e-07 28.4 25.2 5.5 6.8 0.1 11.8 2 1 14 16 16 16 7 UPF0730 unknown protein family WCCH PF03716.14 RUS68462.1 - 9.1e-06 25.2 18.5 1.2e+02 2.5 0.0 12.6 14 0 0 14 14 14 0 WCCH motif Imm57 PF15596.6 RUS68462.1 - 0.3 11.5 9.3 89 3.5 0.2 4.6 1 1 7 8 8 8 0 Immunity protein 57 DNA_mis_repair PF01119.19 RUS68464.1 - 5.2e-10 39.0 0.1 8.1e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Dimer_Tnp_hAT PF05699.14 RUS68465.1 - 0.00013 21.7 0.1 0.00034 20.4 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Histone PF00125.24 RUS68466.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68466.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68466.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68466.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68466.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain AAA_11 PF13086.6 RUS68467.1 - 7.1e-11 42.4 0.0 9.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS68467.1 - 1.7e-08 34.9 0.0 3.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS68467.1 - 1e-05 25.4 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RUS68467.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 RUS68467.1 - 0.00023 20.8 0.0 0.00059 19.4 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 RUS68467.1 - 0.0024 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RUS68467.1 - 0.0099 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 RUS68467.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS68467.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 RUS68467.1 - 0.12 12.8 0.5 0.65 10.4 0.6 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) rve PF00665.26 RUS68468.1 - 3.7e-05 23.9 0.0 9.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 RUS68468.1 - 0.053 13.6 0.0 0.099 12.7 0.0 1.5 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PXPV PF12778.7 RUS68469.1 - 1.3 8.9 47.9 6.4 6.7 12.5 3.5 1 1 2 3 3 3 0 PXPV repeat (3 copies) MSSP PF03940.13 RUS68469.1 - 4.8 6.9 16.6 31 4.3 9.1 2.5 1 1 1 2 2 2 0 Male specific sperm protein rve PF00665.26 RUS68470.1 - 1.6e-17 63.8 0.0 3.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS68470.1 - 1.2e-08 34.9 0.8 2.9e-08 33.7 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RUS68470.1 - 9.5e-05 22.1 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3137 PF11335.8 RUS68470.1 - 0.033 14.1 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Peptidase_M50 PF02163.22 RUS68470.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 RGCC PF15151.6 RUS68471.1 - 0.24 11.6 0.0 0.49 10.6 0.0 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family Herpes_UL35 PF04496.12 RUS68472.1 - 0.17 12.2 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL35 family RT_RNaseH_2 PF17919.1 RUS68473.1 - 2.4e-16 59.6 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68473.1 - 9e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CUB PF00431.20 RUS68474.1 - 4.6e-28 97.8 0.0 5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 CUB domain Exo_endo_phos_2 PF14529.6 RUS68475.1 - 1.4e-16 60.4 3.9 1.9e-16 60.0 0.1 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS68475.1 - 4.3e-15 55.9 0.3 9.7e-15 54.7 0.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3864 PF12980.7 RUS68476.1 - 0.0026 18.0 2.1 37 4.7 0.0 4.8 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3864) Afi1 PF07792.12 RUS68476.1 - 0.027 15.0 4.5 0.05 14.1 4.5 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4228 PF14009.6 RUS68476.1 - 0.048 14.0 6.2 0.13 12.7 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AF-4 PF05110.13 RUS68476.1 - 0.12 10.5 25.7 0.21 9.6 25.7 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF5427 PF10310.9 RUS68476.1 - 0.14 11.1 13.7 0.21 10.5 13.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Vfa1 PF08432.10 RUS68476.1 - 0.14 12.4 33.8 0.27 11.5 33.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 RUS68476.1 - 0.2 10.9 4.3 0.31 10.2 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Beta-lactamase2 PF13354.6 RUS68476.1 - 0.35 10.5 2.3 4.5 6.8 0.2 2.7 2 1 0 2 2 2 0 Beta-lactamase enzyme family DUF3807 PF12720.7 RUS68476.1 - 0.35 11.1 29.7 0.72 10.1 29.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CBM_5_12 PF02839.14 RUS68476.1 - 0.5 11.0 17.9 11 6.8 0.3 4.6 4 0 0 4 4 4 0 Carbohydrate binding domain OATP PF03137.20 RUS68476.1 - 0.6 8.3 7.4 0.92 7.7 7.4 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SRP-alpha_N PF04086.13 RUS68476.1 - 0.68 9.8 27.7 1.3 8.9 27.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RNA_pol_Rpc4 PF05132.14 RUS68476.1 - 1.1 9.7 19.7 2 8.8 19.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CD225 PF04505.12 RUS68476.1 - 1.4 9.1 3.2 17 5.6 0.0 4.0 5 1 1 6 6 6 0 Interferon-induced transmembrane protein SLC12 PF03522.15 RUS68476.1 - 1.6 7.7 16.9 2.7 6.9 16.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 RUS68476.1 - 1.7 8.1 17.3 2.6 7.4 17.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_11 PF13086.6 RUS68476.1 - 1.8 8.3 19.2 3.8 7.2 19.2 1.4 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.11 RUS68476.1 - 1.9 8.5 53.1 3.6 7.6 53.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RPOL_N PF14700.6 RUS68476.1 - 3.3 7.0 21.1 7.3 5.9 21.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Eapp_C PF10238.9 RUS68476.1 - 5.8 7.0 22.4 14 5.8 22.4 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein HTH_ABP1_N PF18107.1 RUS68476.1 - 6.7 6.5 23.4 4.4 7.1 0.1 5.0 5 1 0 5 5 4 0 Fission yeast centromere protein N-terminal domain Tim54 PF11711.8 RUS68476.1 - 6.9 5.4 21.0 16 4.2 21.0 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDE_Tnp_IS1595 PF12762.7 RUS68477.1 - 9.5e-16 58.2 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain zf-HC5HC2H PF13771.6 RUS68477.1 - 0.021 15.0 0.6 0.035 14.4 0.6 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Smr PF01713.21 RUS68478.1 - 6.3e-07 29.7 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Smr domain TRAP_alpha PF03896.16 RUS68478.1 - 0.025 13.8 0.9 0.038 13.2 0.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pes-10 PF07149.11 RUS68478.1 - 0.33 9.9 3.9 0.41 9.6 3.9 1.1 1 0 0 1 1 1 0 Pes-10 UCMA PF17085.5 RUS68478.1 - 0.67 10.0 6.4 1.2 9.1 6.4 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein VIR_N PF15912.5 RUS68478.1 - 2.8 7.4 7.9 3.7 7.1 7.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal FA_desaturase PF00487.24 RUS68479.1 - 4.1e-14 53.0 16.5 6.1e-14 52.5 16.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase PP2C PF00481.21 RUS68482.1 - 0.0001 22.0 0.6 0.00016 21.4 0.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CUB PF00431.20 RUS68485.1 - 3.3e-24 85.3 0.0 1.9e-15 57.1 0.0 2.0 2 0 0 2 2 2 2 CUB domain Miga PF10265.9 RUS68486.1 - 2.7e-55 188.4 0.2 3e-55 188.2 0.2 1.0 1 0 0 1 1 1 1 Mitoguardin Integrase_H2C2 PF17921.1 RUS68487.1 - 6.7e-14 51.7 0.0 1.9e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain SCAN PF02023.17 RUS68487.1 - 5.3e-08 32.6 0.1 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 RUS68487.1 - 5.9e-06 26.1 13.0 0.00062 19.7 3.0 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68487.1 - 0.0065 16.2 10.5 0.078 12.7 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-H2C2 PF09337.10 RUS68487.1 - 0.0074 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_2 PF13696.6 RUS68487.1 - 0.022 14.6 5.8 0.022 14.6 5.8 2.2 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 RUS68488.1 - 3.3e-30 104.1 0.0 9.3e-30 102.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68488.1 - 2.1e-26 92.2 0.0 4.3e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS68488.1 - 7e-13 48.8 0.0 2.2e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS68488.1 - 1.2e-08 34.9 0.0 2.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 RUS68488.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS68489.1 - 5e-22 77.8 0.1 1.1e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain SCAN PF02023.17 RUS68489.1 - 2.7e-13 49.5 0.2 6.3e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 SCAN domain rve PF00665.26 RUS68489.1 - 1.4e-07 31.7 0.0 4.2e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 RUS68489.1 - 2.5e-06 27.6 0.0 6.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 RUS68489.1 - 1.6e-05 24.7 13.0 0.0016 18.5 3.0 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68489.1 - 1.2 9.0 17.9 0.19 11.5 1.5 3.4 3 0 0 3 3 3 0 Zinc knuckle Tox-ODYAM1 PF15642.6 RUS68489.1 - 6.9 5.5 11.3 11 4.8 11.3 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Glyco_hydro_18 PF00704.28 RUS68490.1 - 2.5e-45 155.6 0.0 2.8e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SWIM PF04434.17 RUS68491.1 - 0.12 12.1 0.3 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 SWIM zinc finger DUF445 PF04286.12 RUS68491.1 - 0.28 10.9 39.9 1.7 8.4 29.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) GerPC PF10737.9 RUS68491.1 - 3.4 7.7 33.3 11 6.0 0.5 3.3 1 1 2 3 3 3 0 Spore germination protein GerPC RT_RNaseH_2 PF17919.1 RUS68492.1 - 6.1e-34 116.0 0.0 1.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68492.1 - 2.2e-33 114.7 0.0 3.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68492.1 - 3.2e-22 79.1 0.1 5.5e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS68492.1 - 9.6e-13 48.0 0.1 1.9e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Ub-Mut7C PF14451.6 RUS68493.1 - 0.0035 17.2 5.1 3.4 7.6 0.4 4.4 1 1 2 3 3 3 2 Mut7-C ubiquitin BtrH_N PF14399.6 RUS68493.1 - 0.015 15.5 0.4 11 6.2 0.0 3.3 1 1 2 3 3 3 0 Butirosin biosynthesis protein H, N-terminal Exo_endo_phos PF03372.23 RUS68494.1 - 0.0026 17.3 0.1 0.0057 16.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LPP PF04728.13 RUS68494.1 - 0.81 10.1 4.7 16 5.9 0.4 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4228 PF14009.6 RUS68495.1 - 0.33 11.3 7.4 0.36 11.2 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AF-4 PF05110.13 RUS68495.1 - 0.49 8.4 26.9 0.51 8.4 26.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Otopetrin PF03189.13 RUS68495.1 - 7.2 5.3 5.8 7.3 5.3 5.8 1.1 1 0 0 1 1 1 0 Otopetrin RT_RNaseH_2 PF17919.1 RUS68496.1 - 1.3e-28 98.9 0.0 3.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68496.1 - 2.1e-28 98.7 0.1 5.5e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68496.1 - 2.6e-26 92.5 0.0 4.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS68496.1 - 5.1e-12 46.0 0.0 1.4e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS68496.1 - 0.03 14.1 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain CUB PF00431.20 RUS68497.1 - 2.1e-56 189.0 0.1 2.6e-31 108.2 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.20 RUS68497.1 - 0.085 12.6 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 CUB-like domain RNase_H2_suC PF08615.11 RUS68498.1 - 2.5e-19 69.9 0.2 5.3e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RVT_1 PF00078.27 RUS68499.1 - 4.2e-27 95.1 0.0 6.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS68499.1 - 7.7e-06 26.1 0.0 0.00019 21.6 0.0 2.4 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS68499.1 - 0.00012 22.8 0.9 0.00032 21.4 0.9 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Histone PF00125.24 RUS68500.1 - 1.5e-24 86.8 1.2 1.9e-24 86.5 1.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68500.1 - 5.9e-07 29.7 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68500.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68500.1 - 0.0024 17.9 0.5 0.0028 17.7 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68500.1 - 0.054 13.1 0.7 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF16 PF01519.16 RUS68501.1 - 0.0078 16.7 1.1 0.0078 16.7 1.1 2.1 2 1 0 2 2 2 1 Protein of unknown function DUF16 Laminin_II PF06009.12 RUS68501.1 - 0.032 14.2 5.1 0.033 14.2 4.0 1.5 2 0 0 2 2 2 0 Laminin Domain II ATG16 PF08614.11 RUS68501.1 - 0.24 11.6 7.5 0.39 10.9 7.6 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 RUS68501.1 - 2.4 7.3 8.2 0.66 9.2 5.3 1.5 2 0 0 2 2 2 0 TMPIT-like protein RhoGAP PF00620.27 RUS68502.1 - 2.7e-40 137.7 0.0 3.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Methyltr_RsmF_N PF17125.5 RUS68502.1 - 0.022 15.3 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Baculo_ME53 PF06061.11 RUS68503.1 - 4.3e-06 26.2 9.4 0.35 10.1 0.1 4.1 1 1 2 3 3 3 3 Baculoviridae ME53 Fibrinogen_BP PF08017.11 RUS68503.1 - 1.7e-05 23.5 21.9 2.3e-05 23.0 21.9 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein Cornifin PF02389.15 RUS68503.1 - 0.00018 21.7 0.0 0.0052 17.0 0.0 2.0 1 1 1 2 2 2 1 Cornifin (SPRR) family DUF2345 PF10106.9 RUS68503.1 - 0.00074 19.4 2.0 1.2 9.0 0.3 3.2 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2345) ENTH PF01417.20 RUS68503.1 - 0.0037 17.3 1.9 2.5 8.1 0.4 3.5 1 1 1 2 2 2 2 ENTH domain Pox_polyA_pol_C PF12629.7 RUS68503.1 - 0.036 13.9 2.6 4.9 6.9 0.1 2.2 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase C-terminal domain MJ1316 PF04457.12 RUS68503.1 - 0.059 14.1 15.0 32 5.4 2.2 4.9 1 1 1 2 2 2 0 MJ1316 RNA cyclic group end recognition domain DUF4025 PF13217.6 RUS68503.1 - 5.4 6.9 21.9 25 4.8 0.7 6.9 2 2 4 6 6 6 0 Protein of unknown function (DUF4025) SAM_4 PF18017.1 RUS68504.1 - 9.9e-08 31.8 7.4 1.6 8.7 0.1 5.8 1 1 5 6 6 6 4 SAM domain (Sterile alpha motif) Tape_meas_lam_C PF09718.10 RUS68504.1 - 2e-07 31.0 2.2 1.4 9.1 0.2 5.7 1 1 3 4 4 4 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1997 PF09366.10 RUS68504.1 - 5.9e-06 26.5 2.3 2.3 8.4 0.0 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF1997) CID_GANP PF16766.5 RUS68504.1 - 0.014 15.5 2.2 38 4.6 0.1 4.6 2 1 2 5 5 5 0 Binding region of GANP to ENY2 DUF445 PF04286.12 RUS68504.1 - 0.03 14.1 2.1 0.063 13.1 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1904 PF08921.11 RUS68504.1 - 0.05 13.9 2.0 48 4.3 0.1 4.2 1 1 2 4 4 4 0 Domain of unknown function (DUF1904) DUF2660 PF10859.8 RUS68504.1 - 0.73 10.3 7.8 21 5.7 1.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2660) Ins134_P3_kin PF05770.11 RUS68504.1 - 4.3 6.8 10.4 41 3.6 1.1 4.0 1 1 1 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain DGCR6 PF07324.11 RUS68504.1 - 5.2 6.6 14.8 9.6 5.8 1.3 3.8 1 1 3 4 4 4 0 DiGeorge syndrome critical region 6 (DGCR6) protein eIF3_subunit PF08597.10 RUS68504.1 - 6.7 6.5 5.7 40 4.0 1.8 3.2 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit DUF2587 PF10759.9 RUS68504.1 - 8.8 5.8 10.6 10 5.6 2.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2587) Histone PF00125.24 RUS68505.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68505.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68505.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68505.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68505.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain RVT_1 PF00078.27 RUS68506.1 - 1.6e-43 148.8 0.3 3.8e-43 147.6 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RUS68506.1 - 5.4e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS68506.1 - 3.9e-06 26.7 1.6 4.4e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Chitin_synth_2 PF03142.15 RUS68507.1 - 2e-13 49.8 0.0 2.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 RUS68507.1 - 6.7e-06 26.2 0.2 7.8e-06 25.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RUS68507.1 - 0.025 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RUS68507.1 - 0.088 12.3 0.1 0.11 11.9 0.1 1.3 1 1 0 1 1 1 0 Glycosyl transferase family 21 Integrase_H2C2 PF17921.1 RUS68508.1 - 3.1e-22 78.4 0.1 7.6e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain SCAN PF02023.17 RUS68508.1 - 2.1e-13 49.9 0.2 4e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 SCAN domain rve PF00665.26 RUS68508.1 - 7.9e-07 29.3 0.0 3.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 RUS68508.1 - 1.8e-06 28.0 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 RUS68508.1 - 0.0011 18.9 3.0 0.0011 18.9 3.0 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS68508.1 - 6.4 6.7 16.4 0.038 13.8 5.8 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68508.1 - 9.7 6.0 22.6 0.14 12.0 1.5 3.7 4 0 0 4 4 4 0 Zinc knuckle Histone PF00125.24 RUS68509.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68509.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68509.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68509.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68509.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain RT_RNaseH_2 PF17919.1 RUS68510.1 - 6.2e-34 116.0 0.0 1.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68510.1 - 2.2e-33 114.7 0.0 3.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68510.1 - 3.2e-22 79.1 0.1 5.5e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS68510.1 - 9.6e-13 48.0 0.1 1.9e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 RUS68511.1 - 6.5e-34 116.0 0.0 1.1e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68511.1 - 2.3e-33 114.6 0.0 4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68511.1 - 3.6e-22 79.0 0.1 5.9e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavodoxin_1 PF00258.25 RUS68511.1 - 6.8e-13 49.0 0.0 1.3e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Integrase_H2C2 PF17921.1 RUS68511.1 - 9.7e-13 48.0 0.1 2e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Uteroglobin PF01099.17 RUS68512.1 - 0.032 14.6 0.2 0.13 12.6 0.2 2.1 1 0 0 1 1 1 0 Uteroglobin family FUR PF01475.19 RUS68512.1 - 0.17 12.0 6.1 0.28 11.3 3.9 2.3 2 1 0 2 2 2 0 Ferric uptake regulator family rve PF00665.26 RUS68513.1 - 4e-21 75.4 0.0 7.3e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS68513.1 - 2.1e-05 24.2 0.0 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L36 PF00444.18 RUS68514.1 - 4.1e-10 39.7 1.8 8e-10 38.8 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 Gal-bind_lectin PF00337.22 RUS68516.1 - 2.3e-11 43.4 0.0 3.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin E1-E2_ATPase PF00122.20 RUS68517.1 - 1e-47 162.0 1.1 1.9e-47 161.1 0.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RUS68517.1 - 9.1e-37 127.4 0.3 1.3e-36 126.9 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RUS68517.1 - 0.17 11.6 5.8 0.33 10.6 0.3 2.8 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase RloB PF13707.6 RUS68517.1 - 0.18 12.0 0.2 0.49 10.6 0.0 1.7 2 0 0 2 2 2 0 RloB-like protein Peptidase_M16_M PF16187.5 RUS68518.1 - 8.8e-56 189.2 3.2 9.9e-56 189.1 3.2 1.0 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 UBA_4 PF14555.6 RUS68519.1 - 0.00054 19.7 0.8 14 5.6 0.0 3.1 3 0 0 3 3 3 0 UBA-like domain DUF3878 PF12994.7 RUS68519.1 - 0.0014 18.1 4.3 0.018 14.5 0.6 2.2 1 1 1 2 2 2 2 Domain of unknown function, E. rectale Gene description (DUF3878) Gemini_C4 PF01492.17 RUS68519.1 - 0.0024 17.7 4.8 1.2 9.1 0.2 3.1 1 1 2 3 3 3 1 Geminivirus C4 protein SLED PF12140.8 RUS68519.1 - 0.013 16.0 5.3 0.73 10.4 0.4 2.6 1 1 2 3 3 3 0 SLED domain Cauli_VI PF01693.16 RUS68519.1 - 0.014 15.7 0.4 68 3.9 0.0 3.6 3 0 0 3 3 3 0 Caulimovirus viroplasmin CemA PF03040.14 RUS68519.1 - 0.016 15.1 0.2 0.054 13.4 0.2 1.8 1 1 1 2 2 2 0 CemA family Tricorn_C1 PF14684.6 RUS68519.1 - 0.018 15.1 0.0 4.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Tricorn protease C1 domain DUF1689 PF07954.11 RUS68519.1 - 0.018 15.4 0.1 6.9 7.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) DUF2729 PF10870.8 RUS68519.1 - 0.048 13.5 7.0 13 5.8 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2729) CHD5 PF04420.14 RUS68519.1 - 0.06 13.2 4.3 1.7 8.5 0.3 2.8 1 1 2 3 3 3 0 CHD5-like protein DUF2423 PF10338.9 RUS68519.1 - 0.061 13.6 9.0 3.4 8.0 1.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) XS PF03468.14 RUS68519.1 - 0.076 13.3 0.3 8 6.8 0.1 2.3 2 0 0 2 2 2 0 XS domain DUF1835 PF08874.10 RUS68519.1 - 0.092 13.0 0.4 2 8.6 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) D5_N PF08706.11 RUS68519.1 - 0.2 11.9 3.2 0.58 10.4 3.2 1.8 1 1 0 1 1 1 0 D5 N terminal like DUF2616 PF11077.8 RUS68519.1 - 0.74 9.5 14.3 2.3 7.9 1.4 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2616) Vac14_Fig4_bd PF11916.8 RUS68519.1 - 0.77 9.4 6.6 3.2 7.4 2.1 2.9 1 1 2 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding DUF3698 PF12479.8 RUS68519.1 - 1.1 9.9 5.9 57 4.3 5.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3698) RPAP2_Rtr1 PF04181.13 RUS68519.1 - 2.2 8.7 12.7 6.8 7.1 1.1 3.1 1 1 2 3 3 3 0 Rtr1/RPAP2 family MyTH4 PF00784.17 RUS68519.1 - 3.3 8.2 8.5 21 5.6 0.7 2.9 1 1 2 3 3 3 0 MyTH4 domain EspF PF04806.12 RUS68520.1 - 0.0056 17.1 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 2 EspF protein repeat tRNA-synt_2b PF00587.25 RUS68521.1 - 1.9e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glutaredoxin PF00462.24 RUS68522.1 - 3.3e-05 24.0 9.0 48 4.3 0.1 8.7 6 2 2 8 8 8 0 Glutaredoxin NifU PF01106.17 RUS68522.1 - 0.00057 20.0 2.2 1.3e+02 2.9 0.0 6.8 8 2 2 10 10 10 0 NifU-like domain HpaP PF09483.10 RUS68522.1 - 0.095 13.0 5.9 21 5.4 0.1 4.0 2 1 2 4 4 4 0 Type III secretion protein (HpaP) tRNA-synt_2_TM PF16995.5 RUS68522.1 - 0.16 11.7 1.2 7.5 6.2 0.1 2.9 2 1 2 4 4 4 0 Transmembrane region of lysyl-tRNA synthetase Baculo_FP PF03258.14 RUS68522.1 - 0.19 11.9 0.0 73 3.5 0.0 3.4 2 1 2 4 4 4 0 Baculovirus FP protein zinc_ribbon_16 PF17034.5 RUS68522.1 - 2.8 8.2 9.9 24 5.1 0.1 4.5 2 1 2 4 4 4 0 Zinc-ribbon like family Med31 PF05669.12 RUS68523.1 - 1.2e-07 31.6 0.0 4.2 7.4 0.0 5.3 1 1 5 7 7 7 4 SOH1 ScsC_N PF18312.1 RUS68523.1 - 0.02 14.7 18.7 4.6e+02 0.7 0.0 13.1 21 0 0 21 21 21 0 Copper resistance protein ScsC N-terminal domain RRM_1 PF00076.22 RUS68524.1 - 2.8e-23 81.5 2.8 4.1e-15 55.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS68524.1 - 0.041 13.7 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif NLRC4_HD2 PF17776.1 RUS68524.1 - 1 9.9 0.0 1 9.9 0.0 2.4 2 1 0 2 2 2 0 NLRC4 helical domain HD2 Histone PF00125.24 RUS68527.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68527.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68527.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68527.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68527.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Formyl_trans_N PF00551.19 RUS68528.1 - 0.02 14.6 0.1 4.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Formyl transferase V-SNARE_C PF12352.8 RUS68528.1 - 0.18 12.1 1.9 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus I-set PF07679.16 RUS68529.1 - 8.5e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain TMEM154 PF15102.6 RUS68529.1 - 0.06 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 RUS68529.1 - 0.07 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_3 PF13927.6 RUS68529.1 - 0.079 13.6 0.0 0.3 11.7 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain LapA_dom PF06305.11 RUS68529.1 - 0.087 12.7 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2795 PF11387.8 RUS68529.1 - 0.38 11.0 3.6 26 5.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) Ig_3 PF13927.6 RUS68530.1 - 4.8e-08 33.5 2.2 0.012 16.2 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS68530.1 - 8.9e-05 22.5 2.2 0.01 15.9 1.7 3.1 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 RUS68530.1 - 0.00016 21.7 0.3 0.015 15.4 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS68530.1 - 0.00024 21.4 3.9 0.17 12.2 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain FlaE PF07559.14 RUS68530.1 - 0.027 15.1 0.2 0.046 14.3 0.1 1.4 1 1 0 1 1 1 0 Flagellar basal body protein FlaE Gemini_C4 PF01492.17 RUS68531.1 - 0.017 15.0 1.1 1.1 9.2 0.2 2.1 1 1 1 2 2 2 0 Geminivirus C4 protein DUF2729 PF10870.8 RUS68531.1 - 0.07 13.0 1.6 6.1 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Cauli_VI PF01693.16 RUS68531.1 - 0.081 13.2 0.5 13 6.1 0.0 2.7 3 0 0 3 3 3 0 Caulimovirus viroplasmin UBA_4 PF14555.6 RUS68531.1 - 0.11 12.3 0.2 7 6.6 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain DUF2616 PF11077.8 RUS68531.1 - 0.22 11.2 6.0 1.1 8.9 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) EspF PF04806.12 RUS68532.1 - 0.016 15.5 0.0 9 6.8 0.0 2.2 2 0 0 2 2 2 0 EspF protein repeat Histone PF00125.24 RUS68533.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68533.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68533.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68533.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68533.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone PF00125.24 RUS68534.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68534.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68534.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68534.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68534.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain ABC_tran PF00005.27 RUS68535.1 - 3.9e-38 131.1 1.5 5.2e-22 78.8 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 RUS68535.1 - 1.6e-14 53.7 14.1 2.4e-11 43.5 7.8 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 RUS68535.1 - 4.1e-14 53.1 1.2 1.4e-05 25.1 0.0 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS68535.1 - 1.8e-05 24.3 0.2 1.1 8.7 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS68535.1 - 0.00016 21.9 0.0 0.001 19.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 RUS68535.1 - 0.00091 19.4 1.3 3.1 8.1 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 RUS68535.1 - 0.0075 16.0 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RUS68535.1 - 0.026 14.6 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RUS68535.1 - 0.044 14.3 0.7 0.044 14.3 0.7 2.7 2 1 1 3 3 2 0 AAA domain LIP1 PF15904.5 RUS68535.1 - 0.11 12.9 0.0 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 AAA_33 PF13671.6 RUS68535.1 - 0.13 12.4 1.1 0.3 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 RUS68535.1 - 0.14 12.0 0.0 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 RUS68535.1 - 0.18 12.0 0.7 0.69 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain MRP-L46 PF11788.8 RUS68535.1 - 0.21 12.4 4.9 0.39 11.5 4.9 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 zf-CCHC PF00098.23 RUS68536.1 - 4.7e-06 26.4 3.4 7.7e-06 25.7 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS68536.1 - 0.00023 20.9 3.3 0.00042 20.1 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS68536.1 - 0.0029 17.5 0.1 0.0071 16.3 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS68536.1 - 0.05 13.3 2.7 0.099 12.4 2.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HHV-5_US34A PF17087.5 RUS68537.1 - 6.8e-05 22.9 0.1 39 4.5 0.0 5.7 5 1 1 6 6 6 3 Herpesvirus US34A protein family HHV-5_US34A PF17087.5 RUS68538.1 - 0.0075 16.4 1.8 73 3.6 0.0 4.4 1 1 3 4 4 4 1 Herpesvirus US34A protein family MBOAT PF03062.19 RUS68538.1 - 8.6 5.6 8.0 15 4.8 2.2 2.2 1 1 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family EspF PF04806.12 RUS68540.1 - 0.0056 17.1 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 2 EspF protein repeat Histone PF00125.24 RUS68541.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68541.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68541.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68541.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68541.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain PLAT PF01477.23 RUS68542.1 - 2.5e-28 99.0 0.1 1.3e-21 77.3 0.0 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain ShK PF01549.24 RUS68545.1 - 0.026 15.1 6.6 0.026 15.1 6.6 2.9 2 1 0 2 2 2 0 ShK domain-like Acetyltransf_2 PF00797.17 RUS68546.1 - 2.1e-08 34.3 0.0 3.8e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 N-acetyltransferase SEA PF01390.20 RUS68547.1 - 1.3e-05 25.2 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 SEA domain MafB19-deam PF14437.6 RUS68548.1 - 1.5e-31 109.0 0.3 1.7e-31 108.8 0.3 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 RUS68548.1 - 7.7e-28 96.4 0.7 1e-27 95.9 0.4 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 RUS68548.1 - 0.0016 18.5 1.8 0.0062 16.6 1.5 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 RUS68548.1 - 0.0023 18.1 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 RUS68548.1 - 0.016 15.2 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 RUS68548.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 Inv-AAD PF18785.1 RUS68548.1 - 0.032 14.1 0.3 0.088 12.7 0.3 1.7 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase NAD1 PF18778.1 RUS68548.1 - 0.036 14.1 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 RUS68548.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain S1 PF00575.23 RUS68549.1 - 3e-88 290.2 31.9 6.2e-22 77.7 0.7 6.1 6 0 0 6 6 6 6 S1 RNA binding domain S1_2 PF13509.6 RUS68549.1 - 2.9e-07 30.4 9.5 0.99 9.5 0.0 7.6 5 4 0 5 5 5 2 S1 domain PCB_OB PF17092.5 RUS68549.1 - 8.1e-07 29.8 2.8 4.3 8.1 0.0 5.4 2 1 2 5 5 5 3 Penicillin-binding protein OB-like domain RNase_II_C_S1 PF18614.1 RUS68549.1 - 1.8e-05 24.6 0.3 0.17 11.9 0.0 5.0 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain DUF2110 PF09883.9 RUS68549.1 - 0.021 14.4 2.5 17 4.9 0.0 4.5 6 0 0 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2110) CsrA PF02599.16 RUS68549.1 - 2.2 8.3 17.1 2.1 8.4 0.2 4.8 5 0 0 5 5 5 0 Global regulator protein family BPL_C PF02237.17 RUS68549.1 - 3 7.8 10.4 11 6.0 0.1 4.0 4 0 0 4 4 4 0 Biotin protein ligase C terminal domain I-set PF07679.16 RUS68550.1 - 0.001 19.1 0.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS68550.1 - 0.013 16.1 8.0 0.57 10.8 0.7 3.2 3 0 0 3 3 3 0 Immunoglobulin domain VASt PF16016.5 RUS68550.1 - 0.034 14.5 4.2 0.91 9.9 0.1 2.6 3 0 0 3 3 3 0 VAD1 Analog of StAR-related lipid transfer domain CUB_2 PF02408.20 RUS68550.1 - 0.04 13.7 0.2 18 5.2 0.0 3.2 3 0 0 3 3 3 0 CUB-like domain PcF PF09461.10 RUS68550.1 - 0.28 11.6 4.1 2 8.9 0.4 2.8 2 0 0 2 2 2 0 Phytotoxin PcF protein KA1 PF02149.19 RUS68551.1 - 1.7e-14 53.3 0.0 2.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 RT_RNaseH_2 PF17919.1 RUS68552.1 - 3.5e-33 113.6 0.0 9.1e-33 112.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68552.1 - 1.1e-32 112.4 0.0 2.8e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS68552.1 - 6.9e-22 78.1 0.0 1.2e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS68552.1 - 1.1e-21 76.7 0.1 2.3e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS68552.1 - 4e-21 75.4 0.0 6.3e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain SCAN PF02023.17 RUS68552.1 - 4.6e-13 48.8 0.2 1.3e-12 47.3 0.2 1.9 1 0 0 1 1 1 1 SCAN domain zf-H2C2 PF09337.10 RUS68552.1 - 5e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RUS68552.1 - 6.7e-05 22.6 0.0 0.00026 20.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 RUS68552.1 - 6.8e-05 22.8 13.0 0.0029 17.6 3.0 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS68552.1 - 0.25 11.2 9.9 0.099 12.5 5.8 2.6 2 0 0 2 2 2 0 Zinc knuckle 7tm_1 PF00001.21 RUS68553.1 - 3.5e-08 33.1 14.1 3.5e-08 33.1 14.1 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) CPP1-like PF11833.8 RUS68553.1 - 1.4 8.5 5.9 0.23 11.1 1.0 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 7tm_2 PF00002.24 RUS68554.1 - 3.9e-14 52.5 5.3 3.9e-14 52.5 5.3 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CrgA PF06781.12 RUS68554.1 - 0.084 12.9 0.9 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Cell division protein CrgA FAD_binding_4 PF01565.23 RUS68555.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain RAG1_imp_bd PF12560.8 RUS68557.1 - 8.6e-06 25.5 11.6 0.0027 17.3 11.7 2.2 1 1 0 1 1 1 1 RAG1 importin binding zf-AD PF07776.15 RUS68557.1 - 0.0032 17.7 3.3 0.0032 17.7 3.3 2.7 4 0 0 4 4 4 1 Zinc-finger associated domain (zf-AD) DUF4428 PF14471.6 RUS68557.1 - 0.031 14.2 1.5 0.073 13.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DZR PF12773.7 RUS68557.1 - 3.9 7.6 8.4 0.76 9.9 0.8 2.7 3 0 0 3 3 3 0 Double zinc ribbon RYDR_ITPR PF01365.21 RUS68559.1 - 5.9e-06 25.8 4.5 5.9e-06 25.8 4.5 2.2 1 1 1 2 2 2 1 RIH domain RIH_assoc PF08454.11 RUS68559.1 - 0.0042 16.9 0.7 0.0042 16.9 0.7 2.6 2 1 0 2 2 2 1 RyR and IP3R Homology associated RTTN_N PF14726.6 RUS68559.1 - 0.016 16.0 0.2 0.016 16.0 0.2 3.0 2 2 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning STAR_dimer PF16544.5 RUS68559.1 - 0.37 10.4 2.8 11 5.7 0.3 3.3 2 1 1 3 3 3 0 Homodimerisation region of STAR domain protein DDE_Tnp_IS1595 PF12762.7 RUS68560.1 - 5.7e-15 55.6 0.0 9.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain CNOT1_TTP_bind PF16417.5 RUS68560.1 - 0.04 13.1 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain SURF6 PF04935.12 RUS68561.1 - 2.2 8.0 7.4 0.84 9.4 4.2 1.8 1 1 1 2 2 2 0 Surfeit locus protein 6 Glyco_hydro_18 PF00704.28 RUS68562.1 - 1.1e-19 71.3 3.1 2.4e-19 70.2 3.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short_C2 PF13561.6 RUS68563.1 - 3.3e-40 138.1 0.0 4.7e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS68563.1 - 8.6e-21 74.3 0.3 1e-20 74.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF957 PF06117.11 RUS68563.1 - 0.095 12.3 2.0 0.19 11.3 2.0 1.5 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) DALR_1 PF05746.15 RUS68564.1 - 4.3e-27 94.7 0.1 4.7e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 DALR anticodon binding domain GATase_5 PF13507.6 RUS68565.1 - 7.2e-101 336.6 0.1 1.1e-100 336.0 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 RUS68565.1 - 1.2e-35 123.0 0.0 5.3e-26 91.6 0.0 3.0 2 1 1 3 3 3 2 AIR synthase related protein, C-terminal domain Herpes_ori_bp PF02399.15 RUS68567.1 - 4.1e-07 28.5 0.0 5.7e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Origin of replication binding protein dNK PF01712.19 RUS68568.1 - 2.4e-11 43.9 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Caskin1-CID PF16600.5 RUS68569.1 - 2.4 8.8 12.8 1.2 9.7 1.7 2.4 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain PHD PF00628.29 RUS68572.1 - 7.5e-05 22.6 2.2 0.00014 21.7 2.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS68572.1 - 0.0034 16.9 2.8 0.0089 15.6 2.8 1.7 1 0 0 1 1 1 1 PHD-finger FAM176 PF14851.6 RUS68573.1 - 0.02 14.5 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 FAM176 family Serinc PF03348.15 RUS68573.1 - 0.045 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 RUS68573.1 - 0.062 12.5 0.6 0.064 12.5 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cadherin_C_2 PF16492.5 RUS68573.1 - 0.15 12.8 0.5 0.28 12.0 0.5 1.4 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal RNase_H PF00075.24 RUS68574.1 - 0.054 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 RNase H TMEM252 PF15664.5 RUS68575.1 - 0.19 11.5 1.0 16 5.2 0.0 3.0 1 1 2 3 3 3 0 Transmembrane protein 252 family GerPC PF10737.9 RUS68575.1 - 0.73 9.9 11.5 4 7.5 8.2 2.1 1 1 1 2 2 2 0 Spore germination protein GerPC PIRT PF15099.6 RUS68575.1 - 1.1 8.9 3.9 26 4.4 0.0 3.0 1 1 2 3 3 3 0 Phosphoinositide-interacting protein family WASH-7_mid PF14744.6 RUS68575.1 - 4 6.4 5.7 3.6 6.6 0.6 1.9 1 1 1 2 2 2 0 WASH complex subunit 7 DUF445 PF04286.12 RUS68575.1 - 4.9 6.9 15.1 8.6 6.0 15.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) NUC202 PF08166.12 RUS68577.1 - 0.034 14.2 0.4 1.2 9.3 0.3 2.2 1 1 1 2 2 2 0 NUC202 domain DUF4596 PF15363.6 RUS68577.1 - 0.1 12.8 5.9 1 9.6 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) ANAPC4_WD40 PF12894.7 RUS68579.1 - 0.049 13.9 0.0 0.56 10.5 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 RUS68579.1 - 0.078 11.3 14.8 0.074 11.3 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS68579.1 - 2.4 7.9 13.7 3 7.6 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bac_thur_toxin PF01338.18 RUS68580.1 - 0.12 11.8 0.7 2.9 7.3 0.1 2.0 1 1 1 2 2 2 0 Bacillus thuringiensis toxin PMP22_Claudin PF00822.20 RUS68582.1 - 0.008 16.1 9.7 0.012 15.5 8.8 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RUS68582.1 - 0.033 14.1 12.5 0.18 11.7 12.5 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TMEM43 PF07787.12 RUS68582.1 - 4.3 6.6 6.4 0.15 11.4 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein 43 ER-remodelling PF14755.6 RUS68583.1 - 0.029 14.7 16.4 0.021 15.1 14.4 1.7 1 1 1 2 2 2 0 Intracellular membrane remodeller Ldh_2 PF02615.14 RUS68584.1 - 3e-49 168.0 0.3 3.6e-49 167.7 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase EGF PF00008.27 RUS68585.1 - 3.6e-17 62.3 55.9 2.6e-09 37.2 9.9 5.3 4 1 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 RUS68585.1 - 6.7e-16 58.2 50.1 3.9e-06 27.0 12.2 4.7 3 1 1 4 4 4 4 Calcium-binding EGF domain hEGF PF12661.7 RUS68585.1 - 5.4e-11 42.7 50.0 9.1e-06 26.1 5.9 6.7 5 2 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS68585.1 - 0.00044 20.5 53.9 0.0015 18.9 10.1 5.2 5 1 0 5 5 5 3 EGF-like domain EGF_3 PF12947.7 RUS68585.1 - 0.011 15.9 11.7 0.011 15.9 11.7 5.5 4 2 0 4 4 4 0 EGF domain FXa_inhibition PF14670.6 RUS68585.1 - 0.012 15.9 50.8 0.79 10.1 10.3 4.7 2 1 2 4 4 4 0 Coagulation Factor Xa inhibitory site DUF4696 PF15767.5 RUS68586.1 - 0.0065 15.1 0.0 0.009 14.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) Histone PF00125.24 RUS68587.1 - 2.4e-23 82.9 0.6 3e-23 82.6 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68587.1 - 3.1e-06 27.4 0.0 8.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68587.1 - 0.00065 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68587.1 - 0.0085 16.1 0.3 0.0095 16.0 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Formyl_trans_N PF00551.19 RUS68588.1 - 0.016 15.0 0.1 4.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Formyl transferase V-SNARE_C PF12352.8 RUS68588.1 - 0.17 12.2 2.2 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DEFB136 PF17333.2 RUS68589.1 - 0.0012 18.8 28.6 0.25 11.3 1.0 4.5 4 0 0 4 4 4 4 Beta defensin 136 Glyco_hydro_79n PF03662.14 RUS68591.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain SCO1-SenC PF02630.14 RUS68592.1 - 7.9e-47 158.5 0.0 1.1e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RUS68592.1 - 5.2e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RUS68592.1 - 1e-06 29.0 0.0 2.2e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like CNP_C_terminal PF17839.1 RUS68592.1 - 0.0076 17.0 0.1 0.02 15.6 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of cyclic nucleotide phosphodiesterase DUF4773 PF15998.5 RUS68594.1 - 9.4e-30 103.6 3.1 1.2e-29 103.3 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Shisa PF13908.6 RUS68595.1 - 0.0072 16.6 1.7 0.0072 16.6 1.7 2.1 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator DUF3357 PF11837.8 RUS68595.1 - 0.013 16.0 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF5531 PF17671.1 RUS68595.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5531) MAP17 PF15807.5 RUS68595.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RNF220 PF15926.5 RUS68595.1 - 0.034 13.8 0.3 0.043 13.4 0.3 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 SCIMP PF15050.6 RUS68595.1 - 0.075 13.5 0.0 0.091 13.2 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein MscL PF01741.18 RUS68595.1 - 0.11 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL zf-C2H2_4 PF13894.6 RUS68597.1 - 1e-13 50.8 12.4 0.0018 18.9 0.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS68597.1 - 2.6e-13 49.6 11.8 8.2e-05 22.9 0.2 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS68597.1 - 2.9e-05 24.3 21.7 0.0067 16.8 0.7 4.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 RUS68597.1 - 0.00012 22.4 16.6 0.06 13.8 1.6 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS68597.1 - 0.00082 19.6 14.1 0.21 11.9 2.0 3.9 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 RUS68597.1 - 0.0035 17.2 2.4 0.28 11.1 0.1 2.7 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 RUS68597.1 - 0.0072 15.9 3.7 4.3 7.0 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-MYND PF01753.18 RUS68597.1 - 0.012 15.7 0.7 5.3 7.2 0.0 2.7 2 1 0 2 2 2 0 MYND finger zf-C2HC_2 PF13913.6 RUS68597.1 - 0.02 14.8 12.9 0.026 14.4 1.7 4.1 2 2 1 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 RUS68597.1 - 0.024 14.6 1.2 0.024 14.6 1.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS68597.1 - 0.055 13.2 0.4 0.055 13.2 0.4 3.4 4 1 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RUS68597.1 - 0.064 13.5 4.0 0.44 10.9 0.4 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn_Tnp_IS1595 PF12760.7 RUS68597.1 - 0.14 12.1 3.1 3.5 7.7 0.1 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RAG1 PF10426.9 RUS68597.1 - 0.17 12.0 6.8 2.2 8.5 0.1 3.1 4 0 0 4 4 3 0 Recombination-activating protein 1 zinc-finger domain Zn-ribbon_8 PF09723.10 RUS68597.1 - 0.19 11.9 6.0 0.15 12.2 2.4 2.3 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 RUS68597.1 - 0.2 12.3 5.1 0.64 10.7 0.7 2.3 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ephrin_rec_like PF07699.13 RUS68597.1 - 0.22 11.3 3.5 2.8 7.8 0.1 2.9 3 0 0 3 3 3 0 Putative ephrin-receptor like zf-AN1 PF01428.16 RUS68597.1 - 0.3 11.3 4.9 28 5.0 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-Mss51 PF13824.6 RUS68597.1 - 0.32 11.1 6.6 0.15 12.1 0.4 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2HC5 PF06221.13 RUS68597.1 - 0.44 10.6 6.3 0.34 10.9 1.5 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2_2 PF12756.7 RUS68597.1 - 0.67 10.3 7.7 8.6 6.8 0.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) EspF PF04806.12 RUS68598.1 - 0.034 14.5 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 EspF protein repeat TraK PF06586.11 RUS68598.1 - 0.077 12.7 0.0 0.6 9.8 0.0 1.9 1 1 1 2 2 2 0 TraK protein Gemini_C4 PF01492.17 RUS68599.1 - 0.013 15.3 1.0 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Geminivirus C4 protein UBA_4 PF14555.6 RUS68599.1 - 0.017 14.9 0.2 7 6.6 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain DUF2616 PF11077.8 RUS68599.1 - 0.16 11.7 5.9 1 9.1 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) Tricorn_C1 PF14684.6 RUS68599.1 - 0.18 11.9 0.0 1.9 8.6 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease C1 domain DUF2729 PF10870.8 RUS68599.1 - 0.18 11.7 3.3 6.1 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) EspF PF04806.12 RUS68600.1 - 0.0056 17.1 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 2 EspF protein repeat Glyco_transf_22 PF03901.17 RUS68602.1 - 4.3e-46 158.0 10.2 5.6e-46 157.6 10.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gaa1 PF04114.14 RUS68602.1 - 0.23 10.4 1.4 0.28 10.1 1.4 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component zf-SNAP50_C PF12251.8 RUS68605.1 - 0.1 12.3 0.1 12 5.5 0.1 2.1 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal PIEZO PF15917.5 RUS68612.1 - 0.029 13.9 0.6 0.04 13.4 0.6 1.1 1 0 0 1 1 1 0 Piezo Trypsin PF00089.26 RUS68613.1 - 7.4e-24 84.8 0.5 7.8e-24 84.7 0.5 1.0 1 0 0 1 1 1 1 Trypsin PALP PF00291.25 RUS68614.1 - 5.5e-57 193.4 0.0 6.8e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GP88 PF17338.2 RUS68615.1 - 0.07 12.6 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Gene product 88 CopC PF04234.12 RUS68618.1 - 0.0062 17.5 12.9 17 6.5 0.1 5.1 5 0 0 5 5 5 3 CopC domain Cadherin_4 PF17803.1 RUS68618.1 - 0.022 15.4 8.4 0.022 15.4 8.4 5.8 6 1 0 6 6 6 0 Bacterial cadherin-like domain TRAP-delta PF05404.12 RUS68618.1 - 0.35 10.4 1.7 1.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) SH3_19 PF18597.1 RUS68618.1 - 0.98 9.3 13.5 22 5.0 0.2 5.1 5 0 0 5 5 5 0 Myosin X N-terminal SH3 domain DUF2116 PF09889.9 RUS68619.1 - 0.03 14.3 1.9 0.084 12.9 1.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CbiK PF06180.11 RUS68619.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) RNHCP PF12647.7 RUS68619.1 - 0.15 12.0 2.6 0.35 10.9 2.6 1.6 1 0 0 1 1 1 0 RNHCP domain DnaJ_CXXCXGXG PF00684.19 RUS68619.1 - 1.1 9.7 4.7 25 5.3 0.3 2.4 1 1 1 2 2 2 0 DnaJ central domain Fibrinogen_C PF00147.18 RUS68620.1 - 5.7e-51 173.4 4.0 9.3e-51 172.7 4.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS68620.1 - 0.022 14.7 12.7 0.046 13.6 12.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF848 PF05852.11 RUS68620.1 - 0.063 13.4 4.1 0.043 13.9 1.9 1.9 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PAS_6 PF08348.11 RUS68620.1 - 0.1 12.5 0.3 14 5.6 0.1 2.7 2 0 0 2 2 2 0 YheO-like PAS domain SF-assemblin PF06705.11 RUS68620.1 - 0.14 11.5 7.0 0.33 10.3 6.9 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF1451 PF07295.11 RUS68620.1 - 0.8 9.7 6.5 1.9 8.5 0.5 2.7 1 1 2 3 3 3 0 Zinc-ribbon containing domain IDH PF03971.14 RUS68621.1 - 1.4e-113 380.8 7.2 1.4e-47 162.6 0.1 3.1 1 1 2 3 3 3 3 Monomeric isocitrate dehydrogenase OCD_Mu_crystall PF02423.15 RUS68621.1 - 9.3e-10 37.9 2.0 1.7e-09 37.1 2.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family HTH_15 PF12324.8 RUS68621.1 - 0.0078 16.1 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase FliN_N PF16973.5 RUS68621.1 - 0.12 12.2 0.4 0.33 10.8 0.4 1.7 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal ABC_tran PF00005.27 RUS68622.1 - 2.2e-08 34.7 0.0 4.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS68622.1 - 0.016 14.7 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 RUS68623.1 - 4.3e-14 53.2 0.1 1.3e-13 51.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RUS68623.1 - 0.019 14.4 0.1 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RVT_1 PF00078.27 RUS68624.1 - 6.7e-31 107.5 1.7 2.1e-20 73.2 0.1 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) EMC3_TMCO1 PF01956.16 RUS68626.1 - 1.1e-41 142.5 0.2 1.3e-41 142.2 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Nucleoside_tran PF01733.18 RUS68626.1 - 0.00047 19.6 1.4 0.00076 19.0 0.5 1.7 1 1 1 2 2 2 1 Nucleoside transporter DivIC PF04977.15 RUS68626.1 - 0.0071 16.1 4.1 0.016 15.0 4.1 1.5 1 0 0 1 1 1 1 Septum formation initiator HemX PF04375.14 RUS68626.1 - 0.014 14.7 0.1 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2570 PF10828.8 RUS68626.1 - 0.02 14.7 0.4 0.034 14.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Stevor PF17410.2 RUS68626.1 - 0.028 14.0 1.9 0.046 13.3 1.9 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zf-C2H2_3rep PF18868.1 RUS68626.1 - 0.043 14.5 0.1 0.06 14.0 0.1 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF4446 PF14584.6 RUS68626.1 - 0.049 13.6 0.3 0.076 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GWT1 PF06423.12 RUS68626.1 - 0.052 13.7 1.0 0.083 13.0 0.2 1.8 2 1 0 2 2 2 0 GWT1 Exonuc_VII_L PF02601.15 RUS68626.1 - 0.054 13.1 0.4 0.07 12.7 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Connexin PF00029.19 RUS68626.1 - 0.071 12.9 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Connexin Vpu PF00558.19 RUS68626.1 - 0.086 12.6 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Vpu protein XhlA PF10779.9 RUS68626.1 - 0.098 12.9 3.8 0.39 10.9 3.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA NEMP PF10225.9 RUS68626.1 - 0.18 11.4 1.2 0.28 10.8 1.0 1.4 1 1 0 1 1 1 0 NEMP family DUF1525 PF07511.11 RUS68626.1 - 0.19 11.9 0.6 0.28 11.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF2721 PF11026.8 RUS68626.1 - 0.33 10.9 1.8 0.56 10.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) LapA_dom PF06305.11 RUS68626.1 - 2.1 8.2 9.6 3.9 7.4 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NYD-SP28_assoc PF14775.6 RUS68627.1 - 0.0086 16.2 2.0 0.0086 16.2 2.0 2.2 3 0 0 3 3 3 1 Sperm tail C-terminal domain C_Hendra PF16821.5 RUS68627.1 - 0.025 14.4 1.0 5.6 6.8 0.3 2.3 1 1 1 2 2 2 0 C protein from hendra and measles viruses XendoU PF09412.10 RUS68627.1 - 0.029 13.6 0.6 0.045 13.0 0.6 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU MetRS-N PF09635.10 RUS68627.1 - 0.036 14.6 0.7 0.058 13.9 0.7 1.4 1 0 0 1 1 1 0 MetRS-N binding domain PCP_red PF08369.10 RUS68627.1 - 0.048 13.9 0.2 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Muted PF14942.6 RUS68627.1 - 0.1 12.9 5.9 0.21 12.0 5.9 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein IZUMO PF15005.6 RUS68627.1 - 0.38 11.3 3.5 0.32 11.5 1.4 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Med9 PF07544.13 RUS68627.1 - 0.61 10.2 8.6 0.8 9.8 1.9 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 EMP24_GP25L PF01105.24 RUS68627.1 - 0.63 10.0 4.6 6.3 6.7 0.3 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 RUS68627.1 - 0.83 9.5 6.5 3.8 7.4 0.6 2.7 1 1 1 2 2 2 0 Septum formation initiator V-SNARE PF05008.15 RUS68627.1 - 4.5 7.7 9.9 0.91 9.9 4.1 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Forkhead PF00250.18 RUS68628.1 - 3.7e-40 136.1 0.3 6.2e-40 135.3 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain COX5A PF02284.16 RUS68629.1 - 8.8e-45 150.9 0.0 1.1e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ATP13 PF12921.7 RUS68629.1 - 0.072 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase expression SUIM_assoc PF16619.5 RUS68629.1 - 0.21 11.7 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_1 PF00515.28 RUS68630.1 - 1.5e-10 40.4 14.5 2.6e-09 36.5 0.7 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS68630.1 - 5.3e-09 35.5 13.7 1.9e-07 30.6 0.4 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS68630.1 - 3.8e-08 33.4 2.7 8.5e-08 32.3 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RUS68630.1 - 7.4e-08 32.0 0.7 7.4e-08 32.0 0.7 2.6 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 RUS68630.1 - 4.8e-07 30.0 10.4 0.00042 20.5 3.9 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS68630.1 - 2.4e-05 24.0 5.6 7.7e-05 22.4 0.3 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS68630.1 - 3.9e-05 23.5 0.5 3.9e-05 23.5 0.5 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS68630.1 - 0.00042 20.9 3.6 0.0012 19.4 1.8 2.6 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS68630.1 - 0.00058 19.7 2.8 0.0025 17.6 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS68630.1 - 0.00062 20.4 1.5 0.01 16.6 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS68630.1 - 0.0042 17.6 0.2 0.0042 17.6 0.2 3.8 4 1 0 4 4 3 1 Tetratricopeptide repeat PPR PF01535.20 RUS68630.1 - 0.019 15.2 0.3 11 6.5 0.1 2.8 3 0 0 3 3 2 0 PPR repeat TPR_9 PF13371.6 RUS68630.1 - 0.048 13.8 0.2 0.22 11.7 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Presenilin PF01080.17 RUS68630.1 - 0.1 11.4 22.7 0.13 11.1 22.7 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 RUS68630.1 - 0.19 10.7 26.5 0.28 10.2 26.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 RUS68630.1 - 0.54 8.8 17.6 0.69 8.4 17.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator TPR_17 PF13431.6 RUS68630.1 - 0.73 10.4 6.7 0.64 10.5 1.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS68630.1 - 1.6 8.8 19.9 1.2 9.3 7.5 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat GAGA_bind PF06217.12 RUS68630.1 - 4.3 7.5 23.7 5.8 7.1 23.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family ALMT PF11744.8 RUS68630.1 - 9.8 4.9 20.2 13 4.5 20.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CUB PF00431.20 RUS68631.1 - 5.8e-22 78.1 0.0 5.2e-16 59.0 0.0 2.0 2 0 0 2 2 2 2 CUB domain MFS_1 PF07690.16 RUS68632.1 - 2.4e-23 82.6 16.3 1.3e-12 47.4 0.3 4.0 2 2 2 4 4 4 4 Major Facilitator Superfamily SfLAP PF11139.8 RUS68632.1 - 0.00014 21.4 2.8 0.058 12.8 0.1 2.4 2 0 0 2 2 2 2 Sap, sulfolipid-1-addressing protein ESSS PF10183.9 RUS68632.1 - 0.00081 19.6 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EI24 PF07264.11 RUS68632.1 - 0.003 17.8 0.0 0.028 14.6 0.0 2.7 1 1 2 3 3 3 1 Etoposide-induced protein 2.4 (EI24) DUF4231 PF14015.6 RUS68632.1 - 0.022 15.2 6.1 6.8 7.2 0.0 4.1 3 2 3 6 6 6 0 Protein of unknown function (DUF4231) TctB PF07331.11 RUS68632.1 - 0.049 13.9 6.8 2.4 8.5 1.7 2.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family MFS_1_like PF12832.7 RUS68632.1 - 0.054 12.3 0.6 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 MFS_1 like family DUF4149 PF13664.6 RUS68632.1 - 0.35 11.2 6.3 1.3 9.4 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF2975 PF11188.8 RUS68632.1 - 5.7 6.8 11.6 0.52 10.2 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Lectin_C PF00059.21 RUS68633.1 - 3.1e-15 56.8 0.1 3.1e-15 56.8 0.1 1.4 2 0 0 2 2 2 1 Lectin C-type domain RT_RNaseH PF17917.1 RUS68634.1 - 4.6e-19 68.6 0.0 7.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS68634.1 - 1e-12 47.9 0.0 2.8e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RUS68634.1 - 4.8e-05 23.4 0.7 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain PyrI_C PF02748.15 RUS68634.1 - 0.069 13.1 0.9 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ABC2_membrane_3 PF12698.7 RUS68635.1 - 1.1e-23 83.9 22.9 1.3e-23 83.7 22.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 RUS68635.1 - 0.00062 19.2 18.0 0.00079 18.9 18.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter SHP PF03579.13 RUS68635.1 - 0.021 14.8 4.0 0.075 13.0 4.0 1.9 1 0 0 1 1 1 0 Small hydrophobic protein ATP_synt_H PF05493.13 RUS68635.1 - 0.88 10.1 15.3 0.091 13.2 2.9 2.8 1 1 1 2 2 2 0 ATP synthase subunit H Sulfotransfer_1 PF00685.27 RUS68636.1 - 1.5e-17 64.0 0.0 2.5e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS68636.1 - 2.9e-15 57.2 0.1 3e-14 53.9 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family Hamartin PF04388.12 RUS68637.1 - 1.6e-32 113.1 0.0 3.4e-32 112.0 0.0 1.5 1 1 0 1 1 1 1 Hamartin protein KIAA1430 PF13879.6 RUS68637.1 - 3.6 8.4 10.9 9.7 7.0 10.9 1.8 1 1 0 1 1 1 0 KIAA1430 homologue MCM_OB PF17207.3 RUS68641.1 - 1.8e-25 89.2 1.0 3.4e-25 88.3 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain Umbravirus_LDM PF04817.12 RUS68641.1 - 0.28 10.5 2.5 0.45 9.8 2.5 1.3 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family TAF4 PF05236.14 RUS68642.1 - 0.0094 15.7 1.1 0.016 14.9 1.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CCDC53 PF10152.9 RUS68643.1 - 0.035 14.5 0.5 0.047 14.1 0.5 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RXLR PF16810.5 RUS68643.1 - 0.53 10.7 4.9 0.2 12.1 2.3 1.6 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity MGC-24 PF05283.11 RUS68643.1 - 2.6 8.5 8.4 3.9 7.9 8.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FYVE PF01363.21 RUS68644.1 - 9.8e-21 73.7 11.7 2.1e-20 72.6 11.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger LMP PF04778.12 RUS68644.1 - 0.00073 19.5 6.2 0.00073 19.5 6.2 4.8 1 1 4 5 5 5 1 LMP repeated region HAUS-augmin3 PF14932.6 RUS68644.1 - 0.0014 18.3 11.0 0.0014 18.3 11.0 5.0 1 1 4 5 5 4 2 HAUS augmin-like complex subunit 3 DUF5082 PF16888.5 RUS68644.1 - 0.0015 18.8 17.4 0.0015 18.8 17.4 6.0 2 1 4 6 6 6 2 Domain of unknown function (DUF5082) ERM PF00769.19 RUS68644.1 - 0.0025 17.7 87.5 0.56 10.0 12.1 3.6 1 1 2 3 3 3 2 Ezrin/radixin/moesin family KASH_CCD PF14662.6 RUS68644.1 - 0.01 15.7 7.4 0.01 15.7 7.4 4.8 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH IBR PF01485.21 RUS68644.1 - 0.015 15.5 7.2 0.044 14.0 7.2 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Spc7 PF08317.11 RUS68644.1 - 0.016 14.1 86.7 0.1 11.4 20.2 4.1 1 1 4 5 5 5 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 RUS68644.1 - 0.019 14.9 6.6 0.019 14.9 6.6 8.2 1 1 8 9 9 8 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 RUS68644.1 - 0.17 12.0 88.5 0.91 9.6 17.6 6.4 1 1 4 6 6 6 0 TPR/MLP1/MLP2-like protein Baculo_IE-1 PF05290.11 RUS68644.1 - 0.2 11.6 5.9 0.039 13.9 1.5 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 RUS68644.1 - 0.88 9.7 13.6 2.3 8.3 2.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 RUS68644.1 - 0.96 9.5 11.2 1.1 9.4 8.7 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-B_box PF00643.24 RUS68644.1 - 4.8 7.4 11.5 1.3 9.2 7.1 2.2 2 0 0 2 2 2 0 B-box zinc finger Zn-ribbon_8 PF09723.10 RUS68644.1 - 7.7 6.7 12.3 7e+02 0.5 12.4 3.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-RING_2 PF13639.6 RUS68644.1 - 7.9 6.9 11.5 19 5.7 11.6 1.7 1 1 0 1 1 1 0 Ring finger domain Jnk-SapK_ap_N PF09744.9 RUS68644.1 - 8.3 6.6 90.2 1.3 9.3 18.4 5.0 1 1 4 5 5 5 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 RUS68644.1 - 10 6.5 79.8 4.7 7.6 5.6 4.0 1 1 3 4 4 4 0 Fez1 DUF1758 PF05585.12 RUS68645.1 - 3.5e-15 56.1 0.0 6.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 RUS68645.1 - 7.9e-06 26.3 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS68645.1 - 2.5e-05 24.8 0.0 7.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 RUS68645.1 - 0.0001 22.1 0.5 0.00023 20.9 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease DUF1759 PF03564.15 RUS68645.1 - 0.00065 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RVP_2 PF08284.11 RUS68645.1 - 0.0021 17.9 0.1 0.0038 17.0 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease MINDY_DUB PF04424.13 RUS68645.1 - 0.024 14.7 0.0 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 MINDY deubiquitinase Radical_SAM PF04055.21 RUS68645.1 - 2.2 8.7 5.4 11 6.3 0.1 3.1 3 1 0 3 3 3 0 Radical SAM superfamily ETF PF01012.21 RUS68646.1 - 0.042 13.7 0.5 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Lectin_C PF00059.21 RUS68647.1 - 1.9e-16 60.7 0.0 2.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Epimerase PF01370.21 RUS68648.1 - 5e-81 271.7 0.0 6e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS68648.1 - 2.8e-14 53.3 0.5 2e-11 43.9 0.1 2.9 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS68648.1 - 3.6e-07 29.6 0.0 5.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS68648.1 - 0.031 13.4 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 RUS68649.1 - 1.7e-123 412.3 0.0 1.9e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS68649.1 - 1.8e-55 188.0 0.2 2.4e-55 187.6 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RUS68649.1 - 0.051 12.7 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS68649.1 - 0.21 10.7 0.0 0.43 9.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SSF PF00474.17 RUS68650.1 - 2.2e-09 36.7 10.6 2.6e-09 36.4 10.6 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Acyl_transf_3 PF01757.22 RUS68650.1 - 0.041 12.9 13.6 0.055 12.5 13.6 1.2 1 1 0 1 1 1 0 Acyltransferase family DUF4131 PF13567.6 RUS68650.1 - 2.5 7.8 5.7 5.1 6.7 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 RUS68651.1 - 1.1e-08 34.4 9.1 1.7e-08 33.8 9.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS68651.1 - 2.1e-07 30.2 6.4 2.7e-07 29.8 6.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Eno-Rase_NADH_b PF12242.8 RUS68651.1 - 3.2 7.6 4.4 5.7 6.8 1.4 2.6 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-MYND PF01753.18 RUS68652.1 - 3.2e-09 36.7 13.4 7.2e-09 35.6 13.4 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 RUS68652.1 - 6.6 6.9 9.0 18 5.5 9.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_gyraseB PF00204.25 RUS68653.1 - 1.8e-54 183.8 0.1 3.4e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 RUS68653.1 - 3.9e-31 107.0 0.0 8.2e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 RUS68653.1 - 7.6e-10 39.3 0.5 1.4e-09 38.4 0.5 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GyrB_insert PF18053.1 RUS68653.1 - 2.3e-06 27.6 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain HATPase_c_3 PF13589.6 RUS68653.1 - 0.0011 18.9 0.6 0.0021 17.9 0.6 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RUS68653.1 - 0.0011 19.1 0.2 0.0074 16.5 0.0 2.4 3 1 0 3 3 3 1 Toprim domain Clostridium_P47 PF06597.11 RUS68653.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein PIN_12 PF16289.5 RUS68653.1 - 0.22 12.0 1.9 10 6.5 0.4 2.3 2 0 0 2 2 2 0 PIN domain HALZ PF02183.18 RUS68654.1 - 0.0013 18.9 14.4 0.15 12.3 0.0 3.7 3 0 0 3 3 3 2 Homeobox associated leucine zipper YabA PF06156.13 RUS68654.1 - 0.017 15.8 12.4 0.046 14.4 2.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA ALMT PF11744.8 RUS68654.1 - 0.058 12.2 11.8 0.091 11.6 11.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SlyX PF04102.12 RUS68654.1 - 0.52 11.0 4.7 0.59 10.8 0.3 2.7 2 1 0 2 2 2 0 SlyX NRBF2 PF08961.10 RUS68654.1 - 1.3 8.6 22.4 0.42 10.2 7.5 2.3 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 RUS68654.1 - 1.4 8.7 16.0 0.022 14.5 5.6 2.5 1 1 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 RUS68654.1 - 2.4 8.3 25.1 0.74 10.0 4.3 3.7 1 1 1 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.15 RUS68654.1 - 6.1 6.3 12.3 11 5.5 12.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZapB PF06005.12 RUS68654.1 - 7.2 7.1 20.7 0.18 12.3 3.7 3.0 2 1 1 3 3 3 0 Cell division protein ZapB RF-1 PF00472.20 RUS68655.1 - 9e-42 141.7 1.4 1.2e-41 141.3 1.4 1.1 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 RUS68655.1 - 3e-37 128.4 1.7 1e-36 126.6 0.2 2.0 2 0 0 2 2 2 1 PCRF domain MIR PF02815.19 RUS68655.1 - 0.00035 20.5 0.4 0.00058 19.8 0.2 1.5 1 1 1 2 2 2 1 MIR domain DNA_pol3_delta2 PF13177.6 RUS68656.1 - 3.3e-43 147.3 0.4 4.7e-43 146.8 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 RUS68656.1 - 3.7e-11 43.6 0.0 9e-11 42.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RUS68656.1 - 3.4e-08 33.4 0.4 5.5e-06 26.2 0.0 2.6 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 RUS68656.1 - 5e-06 26.6 0.1 1.2e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 RUS68656.1 - 9.7e-06 25.7 0.4 0.096 12.7 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RUS68656.1 - 1.1e-05 25.8 0.1 8.1e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS68656.1 - 1.5e-05 25.3 0.1 5.1e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS68656.1 - 2.7e-05 24.2 0.3 0.00014 21.8 0.2 2.3 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RUS68656.1 - 2.9e-05 24.6 0.0 5.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 RUS68656.1 - 0.00025 20.9 0.3 0.00038 20.3 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 RUS68656.1 - 0.0006 19.6 0.0 0.0018 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 RUS68656.1 - 0.001 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 RUS68656.1 - 0.0019 18.5 0.1 0.005 17.2 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain TIP49 PF06068.13 RUS68656.1 - 0.002 17.4 0.4 0.33 10.1 0.1 2.5 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 RUS68656.1 - 0.002 17.6 0.3 0.042 13.4 0.3 2.2 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 RUS68656.1 - 0.0046 17.3 0.3 0.08 13.3 0.3 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RUS68656.1 - 0.0051 16.5 0.2 0.015 15.0 0.2 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_pol_Rpb1_3 PF04983.18 RUS68656.1 - 0.0052 16.7 0.0 0.037 14.0 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 3 SKI PF01202.22 RUS68656.1 - 0.012 15.8 0.1 0.034 14.3 0.1 1.8 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.17 RUS68656.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_tranf_2_5 PF13712.6 RUS68656.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family Mg_chelatase PF01078.21 RUS68656.1 - 0.018 14.5 0.0 0.05 13.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 RUS68656.1 - 0.019 14.1 0.1 0.066 12.4 0.1 1.7 1 1 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 RUS68656.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FBPase PF00316.20 RUS68656.1 - 0.048 13.1 0.2 5.6 6.4 0.1 2.4 1 1 1 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain RsgA_GTPase PF03193.16 RUS68656.1 - 0.072 13.0 0.5 0.22 11.4 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 RUS68656.1 - 0.083 13.1 0.2 0.24 11.6 0.2 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS68656.1 - 0.11 13.1 0.3 0.22 12.0 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 RUS68656.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 RUS68656.1 - 0.19 11.4 1.9 2.1 7.9 0.7 2.5 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Tubulin PF00091.25 RUS68657.1 - 5.8e-40 137.6 0.3 5.8e-40 137.6 0.3 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 RUS68657.1 - 1.3e-36 124.7 6.9 1.6e-36 124.5 5.4 2.0 2 0 0 2 2 2 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 RUS68657.1 - 0.0069 16.3 0.6 0.07 13.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)H-binding SHS2_FTSA PF02491.20 RUS68658.1 - 1.4e-22 79.9 1.0 3e-22 78.8 0.2 2.0 2 0 0 2 2 2 1 SHS2 domain inserted in FTSA FtsA PF14450.6 RUS68658.1 - 1.8e-21 76.5 0.3 3.2e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA MreB_Mbl PF06723.13 RUS68658.1 - 6.3e-14 51.5 0.1 9.2e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 RUS68658.1 - 1e-09 37.9 0.0 6.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; EutA PF06277.11 RUS68658.1 - 0.021 13.7 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA ABC_tran PF00005.27 RUS68659.1 - 1.3e-30 106.7 0.0 1.7e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 RUS68659.1 - 6.6e-06 26.8 0.1 9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 RUS68659.1 - 2.3e-05 24.4 0.2 0.0014 18.5 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RUS68659.1 - 0.00017 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RUS68659.1 - 0.00058 19.6 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 RUS68659.1 - 0.0043 17.3 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS68659.1 - 0.0062 16.3 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 RUS68659.1 - 0.0065 16.2 0.0 0.0091 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 RUS68659.1 - 0.023 15.1 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 RUS68659.1 - 0.023 15.0 0.1 0.06 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 RUS68659.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_ATPase PF09818.9 RUS68659.1 - 0.039 12.7 1.1 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATPase PF06745.13 RUS68659.1 - 0.047 13.0 0.1 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 RUS68659.1 - 0.069 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 RUS68659.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 RUS68659.1 - 0.11 13.0 0.1 0.27 11.7 0.0 1.7 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RUS68659.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.19 RUS68659.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_18 PF13238.6 RUS68659.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS68659.1 - 0.16 11.7 0.1 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain EGF PF00008.27 RUS68660.1 - 2.3e-05 24.6 19.4 0.00011 22.4 4.3 2.7 2 1 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 RUS68660.1 - 0.004 17.5 25.3 0.011 16.1 6.0 3.2 2 2 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 RUS68660.1 - 0.0048 17.0 13.4 1 9.5 3.4 2.4 1 1 1 2 2 2 2 Laminin EGF domain hEGF PF12661.7 RUS68660.1 - 0.74 10.5 0.4 0.74 10.5 0.4 3.9 3 1 0 3 3 3 0 Human growth factor-like EGF HA2 PF04408.23 RUS68661.1 - 5e-16 58.9 0.0 1.1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RUS68661.1 - 9.5e-12 45.3 1.1 1.8e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS68661.1 - 2.4e-05 24.2 1.1 0.00022 21.1 1.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS68661.1 - 4.1e-05 23.9 0.1 0.0001 22.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS68661.1 - 0.004 17.5 0.1 0.008 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 RUS68661.1 - 0.0046 16.9 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 RUS68661.1 - 0.028 14.4 0.1 0.34 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RUS68661.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 RUS68661.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 RUS68661.1 - 0.051 12.9 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 RUS68661.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 RUS68661.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 RUS68661.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Lectin_C PF00059.21 RUS68662.1 - 3.1e-16 60.0 0.8 4.1e-16 59.7 0.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain UBA_4 PF14555.6 RUS68663.1 - 0.00089 19.0 0.8 16 5.4 0.0 3.1 3 0 0 3 3 3 3 UBA-like domain TryThrA_C PF12319.8 RUS68663.1 - 0.12 11.8 17.1 0.3 10.6 6.6 2.8 3 0 0 3 3 3 0 Tryptophan-Threonine-rich plasmodium antigen C terminal INTS5_N PF14837.6 RUS68663.1 - 0.13 11.9 7.7 9.8 5.7 0.7 3.2 2 2 0 3 3 3 0 Integrator complex subunit 5 N-terminus DUF2098 PF09871.9 RUS68663.1 - 0.75 10.2 6.0 3.8 7.9 2.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) RasGEF_N PF00618.20 RUS68663.1 - 1.6 9.0 4.5 5.7 7.2 0.4 2.3 2 1 0 2 2 2 0 RasGEF N-terminal motif Phage_TAC_2 PF06894.11 RUS68663.1 - 2.1 8.2 4.0 20 5.0 0.4 2.7 1 1 1 3 3 3 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G OAD_gamma PF04277.13 RUS68663.1 - 2.5 8.8 4.3 3.9 8.1 1.4 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MyTH4 PF00784.17 RUS68663.1 - 5.1 7.6 10.8 20 5.7 1.1 3.1 2 1 0 3 3 3 0 MyTH4 domain Ydc2-catalyt PF09159.10 RUS68663.1 - 6.3 6.5 15.9 47 3.6 15.8 1.9 1 1 1 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 PDEase_I_N PF08499.12 RUS68663.1 - 7.5 6.5 6.1 17 5.3 0.2 2.5 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Histone PF00125.24 RUS68664.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68664.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68664.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68664.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68664.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Formyl_trans_N PF00551.19 RUS68665.1 - 0.0075 16.0 0.1 4.2 7.1 0.0 2.1 2 0 0 2 2 2 2 Formyl transferase V-SNARE_C PF12352.8 RUS68665.1 - 0.15 12.4 2.0 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Histone PF00125.24 RUS68666.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68666.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68666.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS68666.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS68666.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain PDCD2_C PF04194.13 RUS68667.1 - 4.1e-39 134.5 5.9 1.3e-37 129.5 0.0 2.9 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Lar_restr_allev PF14354.6 RUS68667.1 - 0.64 10.4 6.7 2.1 8.8 0.1 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar DEAD_2 PF06733.15 RUS68670.1 - 5.5e-51 172.7 0.6 8.1e-51 172.1 0.0 1.6 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 RUS68670.1 - 2.6e-43 147.9 0.1 6e-43 146.8 0.1 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 RUS68670.1 - 4.7e-06 26.7 0.1 0.00019 21.5 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RUS68670.1 - 0.00016 21.5 0.1 0.38 10.5 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_11 PF13086.6 RUS68670.1 - 0.0054 16.6 0.1 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 RUS68670.1 - 0.0082 15.6 0.1 0.39 10.2 0.0 2.4 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 RUS68670.1 - 0.021 15.1 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RUS68670.1 - 0.026 14.9 0.0 0.33 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain SNF2_N PF00176.23 RUS68670.1 - 0.031 13.0 0.1 2.5 6.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain Myb_DNA-bind_4 PF13837.6 RUS68670.1 - 0.07 13.5 0.5 4.9 7.6 0.2 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_30 PF13604.6 RUS68670.1 - 0.22 11.2 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNase_H PF00075.24 RUS68672.1 - 3.2e-13 50.1 0.0 5.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS68672.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like RT_RNaseH PF17917.1 RUS68672.1 - 0.019 15.3 0.0 5.1 7.4 0.0 2.7 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase ATPase_2 PF01637.18 RUS68672.1 - 0.033 14.1 0.5 0.052 13.5 0.5 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Myb_DNA-bind_3 PF12776.7 RUS68672.1 - 0.28 12.2 1.1 9.7 7.2 0.0 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Chitin_synth_2 PF03142.15 RUS68673.1 - 3.8e-23 81.9 15.5 3.1e-20 72.3 1.3 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RUS68673.1 - 7.2e-12 45.6 2.2 7.2e-12 45.6 2.2 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RUS68673.1 - 1.7e-05 24.8 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3327 PF11806.8 RUS68673.1 - 0.059 14.1 0.0 0.09 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) RVT_1 PF00078.27 RUS68674.1 - 2.6e-45 154.6 0.3 2.6e-45 154.6 0.3 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS68674.1 - 3.9e-21 75.1 0.0 1.9e-20 72.9 0.0 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS68674.1 - 4.8e-07 29.5 0.4 3.1e-06 26.9 0.4 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 RUS68674.1 - 0.00014 22.1 1.0 0.00026 21.2 0.0 1.9 2 0 0 2 2 2 1 RNase H Myb_DNA-bind_3 PF12776.7 RUS68674.1 - 6.5 7.8 8.5 20 6.3 0.0 4.1 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3365 PF11845.8 RUS68675.1 - 0.082 13.2 0.5 0.14 12.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) RNase_H PF00075.24 RUS68676.1 - 2e-05 24.8 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RT_RNaseH PF17917.1 RUS68676.1 - 0.023 15.0 0.0 4.6 7.6 0.1 2.6 2 1 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Cu_amine_oxid PF01179.20 RUS68677.1 - 2.1e-25 89.5 0.0 3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 RUS68677.1 - 1.6e-09 37.9 0.0 2.5e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 Copper amine oxidase, N2 domain VirB8 PF04335.13 RUS68677.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein Ribosomal_S6 PF01250.17 RUS68678.1 - 8.8e-18 64.4 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Sulfotransfer_1 PF00685.27 RUS68679.1 - 1.6e-24 86.8 0.3 2e-24 86.5 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS68679.1 - 7.9e-17 62.4 0.6 1.1e-11 45.6 0.6 2.1 1 1 1 2 2 2 2 Sulfotransferase family Peptidase_M10 PF00413.24 RUS68680.1 - 5.8e-31 107.5 0.3 7.7e-31 107.1 0.3 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 RUS68680.1 - 8.5e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Prim_Zn_Ribbon PF08273.12 RUS68681.1 - 0.042 14.1 0.7 0.073 13.4 0.7 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.7 RUS68681.1 - 0.089 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Na_sulph_symp PF00939.19 RUS68684.1 - 1.8e-65 221.8 3.3 8.2e-39 133.9 3.2 2.0 1 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS68684.1 - 1.6e-26 93.2 20.9 2e-11 43.7 0.0 3.0 2 1 1 3 3 3 3 Citrate transporter 7TM_GPCR_Srx PF10328.9 RUS68685.1 - 2.1e-08 34.1 14.6 2.1e-08 34.1 14.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx ASC PF00858.24 RUS68686.1 - 9.8e-35 120.4 0.3 2.6e-34 118.9 0.3 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel VWA PF00092.28 RUS68687.1 - 1.4e-33 116.6 0.3 1.8e-32 113.0 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS68687.1 - 1.9e-11 44.6 0.1 8.4e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS68687.1 - 0.0034 17.3 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 RUS68687.1 - 0.0073 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Glyco_hydro_25 PF01183.20 RUS68687.1 - 0.06 13.5 0.1 0.23 11.6 0.1 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 25 SRRM_C PF15230.6 RUS68689.1 - 0.59 10.7 6.5 0.36 11.4 2.0 2.4 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus IMPDH PF00478.25 RUS68690.1 - 1.3e-120 402.6 12.1 1.4e-120 402.4 12.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RUS68690.1 - 1.1e-08 34.6 10.2 1.6e-08 34.0 8.6 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 RUS68690.1 - 2e-08 34.0 9.2 3e-08 33.4 9.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase NanE PF04131.14 RUS68690.1 - 0.00018 20.7 2.3 0.00039 19.7 2.3 1.5 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 RUS68690.1 - 0.00023 20.5 9.7 0.077 12.2 3.5 2.4 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 RUS68690.1 - 0.00023 20.7 4.8 0.08 12.4 0.6 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein B12-binding PF02310.19 RUS68690.1 - 0.0021 18.1 0.6 0.0021 18.1 0.6 1.7 2 0 0 2 2 2 1 B12 binding domain Response_reg PF00072.24 RUS68690.1 - 0.003 17.7 0.1 0.0068 16.6 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Glu_synthase PF01645.17 RUS68690.1 - 0.045 12.9 13.0 0.012 14.7 8.8 2.0 1 1 1 2 2 2 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 RUS68690.1 - 0.12 11.7 3.5 5 6.5 0.4 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 RUS68690.1 - 0.16 11.4 7.2 0.26 10.7 0.9 2.2 2 0 0 2 2 2 0 PcrB family TMP-TENI PF02581.17 RUS68690.1 - 0.21 10.9 6.3 0.33 10.3 3.1 2.1 1 1 1 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 RUS68690.1 - 7.1 5.9 9.3 0.45 9.8 2.7 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG GTP_EFTU PF00009.27 RUS68691.1 - 3.1e-37 128.0 0.9 2.2e-35 122.0 0.9 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RUS68691.1 - 3.5e-37 126.7 1.0 1.6e-36 124.6 1.0 2.2 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 RUS68691.1 - 5.7e-17 61.3 0.7 2.2e-16 59.4 0.4 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 RUS68691.1 - 5.3e-10 39.4 0.1 1.3e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 RUS68691.1 - 1.7e-07 31.0 0.0 5.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 RUS68691.1 - 2.6e-07 30.9 3.7 0.00024 21.4 0.3 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Arf PF00025.21 RUS68691.1 - 5.4e-07 29.2 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 RUS68691.1 - 0.00016 20.8 1.3 0.0045 16.0 0.2 2.9 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 RUS68691.1 - 0.00024 20.6 2.5 0.00047 19.6 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RUS68691.1 - 0.00024 21.0 0.1 0.039 13.9 0.0 2.6 1 1 1 2 2 2 1 RsgA GTPase Roc PF08477.13 RUS68691.1 - 0.0025 18.0 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 RUS68691.1 - 0.0056 16.2 0.3 0.032 13.8 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF3450 PF11932.8 RUS68691.1 - 0.011 15.1 0.8 0.89 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PCI PF01399.27 RUS68691.1 - 0.16 12.5 1.0 0.75 10.3 0.1 2.2 2 0 0 2 2 2 0 PCI domain KH_5 PF13184.6 RUS68692.1 - 1.2e-23 82.9 1.7 1.6e-21 76.2 0.1 2.8 2 0 0 2 2 2 1 NusA-like KH domain NusA_N PF08529.11 RUS68692.1 - 2.6e-18 66.5 3.9 2.6e-18 66.5 3.9 2.9 3 1 0 3 3 3 1 NusA N-terminal domain HHH_5 PF14520.6 RUS68692.1 - 5e-16 59.0 3.4 1.6e-07 31.8 0.2 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 RUS68692.1 - 0.00016 21.4 5.4 0.038 13.8 0.3 3.6 3 0 0 3 3 3 2 Bacterial RNA polymerase, alpha chain C terminal domain KH_2 PF07650.17 RUS68692.1 - 0.00025 20.8 0.3 0.0021 17.8 0.1 2.6 2 0 0 2 2 2 1 KH domain S1 PF00575.23 RUS68692.1 - 0.00085 19.6 0.6 0.0072 16.6 0.1 2.7 2 0 0 2 2 2 1 S1 RNA binding domain DUF4332 PF14229.6 RUS68692.1 - 0.012 15.8 0.3 7.1 6.9 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4332) KH_1 PF00013.29 RUS68692.1 - 0.021 14.7 0.2 5.5 6.9 0.1 3.2 3 0 0 3 3 3 0 KH domain HHH_2 PF12826.7 RUS68692.1 - 0.048 13.8 3.3 0.31 11.1 0.2 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sigma70_r4_2 PF08281.12 RUS68692.1 - 0.15 11.7 0.4 3.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 TfoX_C PF04994.13 RUS68692.1 - 0.18 11.9 0.7 2 8.5 0.1 2.8 3 0 0 3 3 3 0 TfoX C-terminal domain FliG_N PF14842.6 RUS68692.1 - 1.1 9.8 6.2 0.84 10.2 3.0 2.5 2 0 0 2 2 2 0 FliG N-terminal domain DUF1192 PF06698.11 RUS68692.1 - 7.4 6.7 7.8 0.29 11.2 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF2045 PF09741.9 RUS68693.1 - 0.022 14.2 2.5 6.2 6.1 0.1 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2045) DUF2507 PF10702.9 RUS68693.1 - 0.12 12.3 0.2 0.57 10.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2507) DUF1416 PF07210.12 RUS68693.1 - 0.14 12.0 5.5 12 5.9 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1416) RT_RNaseH_2 PF17919.1 RUS68694.1 - 5.8e-27 93.7 0.0 2.6e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68694.1 - 2e-15 56.9 0.0 5.8e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 RUS68694.1 - 5e-05 23.5 0.0 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 RUS68694.1 - 6.3e-05 23.5 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS68694.1 - 0.00024 21.7 0.0 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 RUS68694.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease BH4 PF02180.17 RUS68694.1 - 0.14 12.0 0.6 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Bcl-2 homology region 4 Kinesin PF00225.23 RUS68695.1 - 4.8e-56 190.1 0.2 6.4e-56 189.7 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Cep57_MT_bd PF06657.13 RUS68695.1 - 0.92 10.0 4.2 11 6.6 1.3 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Arginosuc_synth PF00764.19 RUS68698.1 - 1.3e-66 225.5 0.0 1.6e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 RUS68698.1 - 5.5e-05 22.8 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 RUS68698.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Thyroglobulin_1 PF00086.18 RUS68699.1 - 2.5e-19 68.7 18.2 1.6e-12 46.9 4.8 3.4 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Mid2 PF04478.12 RUS68699.1 - 2.3e-05 24.3 2.0 4.1e-05 23.5 2.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 RUS68699.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orthoreo_P10 PF07204.11 RUS68699.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.6 RUS68699.1 - 0.085 13.7 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RUS68699.1 - 0.57 10.0 10.4 0.95 9.3 10.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3139 PF11337.8 RUS68700.1 - 8.8 7.1 9.7 17 6.2 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) fn3 PF00041.21 RUS68701.1 - 0.011 16.0 0.1 0.081 13.3 0.1 2.5 2 1 0 2 2 2 0 Fibronectin type III domain Lep_receptor_Ig PF06328.11 RUS68701.1 - 0.041 13.8 0.4 0.081 12.9 0.4 1.5 1 0 0 1 1 1 0 Ig-like C2-type domain BTB PF00651.31 RUS68702.1 - 2.8e-19 69.4 0.0 3.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Acyl-ACP_TE PF01643.17 RUS68703.1 - 4.2e-12 45.9 0.0 2.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Acyl-ACP thioesterase DarA_C PF18789.1 RUS68703.1 - 0.16 12.3 0.1 0.92 9.9 0.0 2.1 2 0 0 2 2 2 0 Defence against restriction A C-terminal RVT_1 PF00078.27 RUS68704.1 - 5.4e-46 156.9 0.3 1.2e-45 155.7 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS68704.1 - 1.1e-05 25.6 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 RNase H RFX_DNA_binding PF02257.15 RUS68705.1 - 0.006 17.2 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 RUS68705.1 - 0.13 12.2 2.7 0.16 11.9 0.1 2.4 3 1 1 4 4 4 0 CDC6, C terminal winged helix domain RVT_1 PF00078.27 RUS68706.1 - 3.3e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Beta_helix PF13229.6 RUS68707.1 - 0.063 13.1 0.2 0.26 11.2 0.2 2.0 1 1 0 1 1 1 0 Right handed beta helix region TRM PF02005.16 RUS68709.1 - 1.4e-39 136.3 0.8 3.4e-31 108.8 0.2 2.2 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase KI67R PF08065.12 RUS68709.1 - 0.46 11.0 4.4 1.2 9.7 4.4 1.7 1 0 0 1 1 1 0 KI67R (NUC007) repeat PAN_1 PF00024.26 RUS68710.1 - 1.7e-18 66.4 19.7 3.9e-08 33.1 0.6 3.3 1 1 2 3 3 3 3 PAN domain PAN_2 PF08276.11 RUS68710.1 - 0.025 14.7 14.7 0.16 12.1 2.9 3.3 3 0 0 3 3 3 0 PAN-like domain TMEM223 PF14640.6 RUS68710.1 - 0.13 12.4 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 223 Carb_bind PF10645.9 RUS68710.1 - 6.5 7.1 8.1 26 5.1 0.1 3.4 3 0 0 3 3 3 0 Carbohydrate binding EspF PF04806.12 RUS68711.1 - 0.0056 17.1 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 2 EspF protein repeat Histone PF00125.24 RUS68712.1 - 1.9e-21 76.8 1.2 2.4e-21 76.5 1.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS68712.1 - 3.7e-06 27.1 0.1 9.1e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS68712.1 - 0.00018 22.0 0.0 0.00033 21.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF4665 PF15679.5 RUS68712.1 - 0.013 16.1 3.2 0.022 15.4 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) NFACT-R_2 PF18297.1 RUS68712.1 - 0.017 15.3 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 NFACT protein RNA binding domain YscO-like PF16789.5 RUS68712.1 - 0.023 14.8 0.3 0.033 14.2 0.3 1.4 1 1 0 1 1 1 0 YscO-like protein Transposase_1 PF01359.18 RUS68713.1 - 3.4e-19 68.4 0.0 7.7e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 RUS68713.1 - 7.8e-05 22.8 0.2 0.00016 21.8 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS68713.1 - 0.0003 21.3 0.1 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS68713.1 - 0.0016 18.5 0.3 0.0063 16.6 0.0 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 RUS68713.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF977 PF06163.11 RUS68713.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF4817 PF16087.5 RUS68713.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DDE_3 PF13358.6 RUS68713.1 - 0.12 12.1 0.0 1.4 8.7 0.0 2.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Fibrinogen_C PF00147.18 RUS68714.1 - 2.8e-42 145.0 1.4 3.3e-42 144.8 1.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spem1 PF15670.5 RUS68714.1 - 0.037 13.6 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Fibrinogen_C PF00147.18 RUS68715.1 - 5.3e-46 157.2 9.2 6.5e-46 156.9 9.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Glyco_hydro_20 PF00728.22 RUS68716.1 - 6.3e-09 35.7 0.0 2.4e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF3486 PF11985.8 RUS68716.1 - 0.042 14.3 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) MULE PF10551.9 RUS68717.1 - 1.4e-18 67.1 0.3 4e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 RUS68717.1 - 6.2e-07 30.0 1.3 2.8e-06 28.0 0.5 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF5575 PF17738.1 RUS68717.1 - 4.6e-05 22.6 0.0 0.00071 18.7 0.0 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF5575) DUF4911 PF16256.5 RUS68717.1 - 1.6 8.8 8.0 39 4.3 0.2 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4911) RRM_1 PF00076.22 RUS68718.1 - 2.9e-17 62.2 0.0 5.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS68718.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surface_antigen PF11054.8 RUS68719.1 - 1.2e-07 31.6 7.1 0.099 12.3 0.4 4.2 1 1 2 3 3 3 3 Sporozoite TA4 surface antigen GxDLY PF14607.6 RUS68719.1 - 0.0011 18.8 0.5 0.71 9.7 0.0 2.9 1 1 2 3 3 3 2 N-terminus of Esterase_SGNH_hydro-type Ephrin PF00812.17 RUS68719.1 - 0.0012 18.8 10.2 0.17 11.9 2.5 3.3 1 1 2 3 3 3 2 Ephrin HNF-1A_C PF04813.12 RUS68719.1 - 0.0015 19.3 0.1 4.2 8.2 0.1 3.2 1 1 2 3 3 3 2 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Trimer_CC PF08954.11 RUS68719.1 - 0.0032 17.0 2.5 70 3.1 0.0 6.0 5 1 2 7 7 7 0 Trimerisation motif DUF1831 PF08866.10 RUS68719.1 - 0.11 12.9 0.1 4.9 7.6 0.0 2.1 1 1 1 2 2 2 0 Putative amino acid metabolism Nab2p_Zf1 PF18260.1 RUS68719.1 - 1.4 8.9 27.8 1.1e+02 2.8 0.0 9.4 11 0 0 11 11 11 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 C8 PF08742.11 RUS68719.1 - 8.2 6.9 14.2 8.9 6.8 1.6 3.4 1 1 3 4 4 4 0 C8 domain Amino_oxidase PF01593.24 RUS68721.1 - 1.4e-28 100.4 0.0 1.5e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 RUS68721.1 - 0.18 11.0 0.1 0.26 10.5 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PGM_PMM_II PF02879.16 RUS68722.1 - 2.7e-13 50.4 0.1 5.1e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II NTP_transferase PF00483.23 RUS68722.1 - 9.3e-07 28.7 0.9 0.0044 16.6 0.2 2.3 1 1 1 2 2 2 2 Nucleotidyl transferase Glyco_hydro_77 PF02446.17 RUS68722.1 - 5.5e-06 25.5 0.0 5.8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase Glyco_transf_5 PF08323.11 RUS68722.1 - 0.00025 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase_C PF02806.18 RUS68723.1 - 3.8e-25 88.2 0.0 1.2e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 RUS68723.1 - 2.8e-14 53.2 0.1 6.7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 RUS68723.1 - 2.4e-12 47.1 2.8 1.1e-07 31.7 0.2 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 RUS68723.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain RVT_1 PF00078.27 RUS68725.1 - 4.1e-25 88.6 1.2 1.1e-19 70.8 0.1 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RUS68726.1 - 4e-18 65.0 0.1 5e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RUS68726.1 - 1.8e-07 30.9 5.1 2.8e-07 30.3 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 RUS68726.1 - 0.00038 20.5 0.2 0.0017 18.4 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC_3 PF13917.6 RUS68726.1 - 0.0017 18.2 2.0 0.0027 17.7 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_occluded PF16842.5 RUS68726.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCHC_2 PF13696.6 RUS68726.1 - 0.028 14.3 3.0 0.04 13.7 3.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_3 PF08777.11 RUS68726.1 - 0.034 14.2 0.1 0.038 14.0 0.1 1.1 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 RUS68726.1 - 0.035 14.1 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RUS68726.1 - 0.041 13.5 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 RUS68726.1 - 0.062 13.0 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Calcipressin eIF3g PF12353.8 RUS68726.1 - 0.21 12.0 0.8 0.27 11.6 0.8 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 RUS68726.1 - 0.22 11.3 3.6 0.71 9.6 4.0 1.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PI_PP_I PF18363.1 RUS68727.1 - 0.017 15.3 0.1 0.055 13.7 0.0 1.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain DnaJ_C PF01556.18 RUS68729.1 - 1.5e-44 151.7 0.0 2.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS68729.1 - 2.7e-27 94.7 1.2 3.9e-27 94.1 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RUS68729.1 - 3.7e-12 46.4 14.9 6.9e-12 45.5 14.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RUS68729.1 - 0.033 14.2 17.0 0.32 11.0 3.0 3.3 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 RUS68729.1 - 2.7 8.3 23.2 3.3 8.0 0.8 4.8 5 0 0 5 5 5 0 Family of unknown function (DUF5351) TackOD1 PF18551.1 RUS68729.1 - 6.1 6.5 9.9 7.6 6.2 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 RUS68729.1 - 9.6 6.3 8.0 4.4 7.3 3.9 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HSP70 PF00012.20 RUS68730.1 - 6.4e-251 833.7 17.0 7.4e-251 833.6 17.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS68730.1 - 2.5e-12 46.2 0.4 2.5e-12 46.2 0.4 2.5 3 1 0 3 3 3 1 MreB/Mbl protein DMRL_synthase PF00885.19 RUS68730.1 - 0.0083 16.0 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 6,7-dimethyl-8-ribityllumazine synthase FGGY_C PF02782.16 RUS68730.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SICA_alpha PF12887.7 RUS68730.1 - 0.49 10.2 4.6 0.2 11.5 1.6 1.9 2 0 0 2 2 2 0 SICA extracellular alpha domain GrpE PF01025.19 RUS68731.1 - 6.9e-51 172.2 3.3 7.7e-51 172.1 3.3 1.0 1 0 0 1 1 1 1 GrpE Ribosomal_L13 PF00572.18 RUS68732.1 - 8.3e-42 142.4 0.1 9.7e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Matrilin_ccoil PF10393.9 RUS68734.1 - 0.11 12.4 0.2 7.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Fibrinogen_C PF00147.18 RUS68735.1 - 7.5e-53 179.6 6.6 9.4e-53 179.3 6.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Pyridoxal_deC PF00282.19 RUS68736.1 - 8.5e-98 327.5 0.0 9.7e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RUS68736.1 - 3.8e-05 23.1 0.0 7e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RUS68736.1 - 0.084 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V SepSecS PF05889.13 RUS68736.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pkinase PF00069.25 RUS68737.1 - 2e-15 56.8 0.0 3.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS68737.1 - 2.6e-07 30.2 0.0 1.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS68737.1 - 0.0093 14.8 0.0 0.0093 14.8 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase PARM PF17061.5 RUS68737.1 - 1.3 9.1 17.0 1.7 8.7 17.0 1.1 1 0 0 1 1 1 0 PARM SMP_LBD PF17047.5 RUS68740.1 - 6.6e-42 143.0 0.0 8.1e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 RUS68740.1 - 0.0036 17.6 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain SPRY PF00622.28 RUS68742.1 - 5.6e-15 55.5 0.0 2.3e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Tom37 PF10568.9 RUS68743.1 - 3.5e-26 92.0 0.0 5.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 RUS68743.1 - 3.9e-25 88.5 0.0 7.5e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS68743.1 - 1.5e-18 66.3 0.0 2.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS68743.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS68743.1 - 0.053 13.7 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LMF1 PF06762.14 RUS68744.1 - 1.7e-33 116.4 3.9 3e-33 115.6 3.9 1.4 1 0 0 1 1 1 1 Lipase maturation factor AhpC-TSA PF00578.21 RUS68745.1 - 3.4e-13 49.6 0.0 4.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 RUS68745.1 - 2.1e-12 46.7 0.0 4.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 RUS68745.1 - 3.4e-07 30.1 0.1 4.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin AAA_2 PF07724.14 RUS68746.1 - 3.8e-40 137.8 0.2 4.3e-40 137.6 0.2 1.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 RUS68746.1 - 1.6e-17 64.2 0.1 1.8e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS68746.1 - 5.1e-09 36.2 0.0 7.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RUS68746.1 - 2.9e-05 23.6 0.1 0.0016 17.9 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RUS68746.1 - 3.2e-05 24.2 0.0 6.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 RUS68746.1 - 0.00016 20.9 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 RUS68746.1 - 0.00022 21.0 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 RUS68746.1 - 0.00083 19.4 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS68746.1 - 0.0011 19.5 0.0 0.0013 19.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RUS68746.1 - 0.0025 17.6 0.4 0.049 13.4 0.3 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 RUS68746.1 - 0.0026 17.3 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 RUS68746.1 - 0.003 18.0 0.0 0.0047 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RUS68746.1 - 0.0034 17.6 0.0 0.0039 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RUS68746.1 - 0.0063 16.3 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RUS68746.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 RUS68746.1 - 0.017 15.3 0.0 0.025 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain IPT PF01745.16 RUS68746.1 - 0.042 13.2 0.1 0.079 12.3 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase CPT PF07931.12 RUS68746.1 - 0.044 13.6 0.0 0.048 13.5 0.0 1.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SRP54 PF00448.22 RUS68746.1 - 0.056 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Roc PF08477.13 RUS68746.1 - 0.058 13.6 0.0 0.086 13.1 0.0 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 RUS68746.1 - 0.063 13.0 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 RUS68746.1 - 0.065 13.1 0.1 0.28 11.1 0.1 1.9 1 1 0 1 1 1 0 NACHT domain TniB PF05621.11 RUS68746.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.5 1 1 1 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 RUS68746.1 - 0.098 12.6 0.8 0.79 9.6 0.4 1.9 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 RUS68746.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 RUS68746.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BPL_LplA_LipB PF03099.19 RUS68747.1 - 2.4e-07 30.7 0.0 1.6e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThiF PF00899.21 RUS68748.1 - 6.3e-32 110.9 0.5 6.9e-32 110.7 0.5 1.0 1 0 0 1 1 1 1 ThiF family ELFV_dehydrog PF00208.21 RUS68748.1 - 0.0025 17.6 0.3 0.0026 17.5 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 RUS68748.1 - 0.004 17.6 0.3 0.0062 17.0 0.3 1.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 RUS68748.1 - 0.006 16.8 1.6 0.011 15.9 1.6 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 RUS68748.1 - 0.029 14.4 1.1 0.033 14.3 1.1 1.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 RUS68748.1 - 0.048 13.3 1.0 0.058 13.0 1.0 1.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 RUS68748.1 - 0.087 13.1 2.3 0.13 12.6 1.3 1.7 1 1 0 1 1 1 0 TrkA-N domain Gp_dh_N PF00044.24 RUS68748.1 - 0.093 13.1 1.1 0.12 12.7 1.1 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PglD_N PF17836.1 RUS68748.1 - 0.4 11.3 7.0 0.48 11.1 3.0 2.1 1 1 1 2 2 2 0 PglD N-terminal domain 7tm_1 PF00001.21 RUS68749.1 - 8.1e-06 25.3 5.0 1.2e-05 24.8 5.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS68749.1 - 0.0016 18.1 7.1 0.014 15.0 1.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx DoxX_2 PF13564.6 RUS68749.1 - 0.077 13.1 1.4 0.25 11.5 0.4 2.2 1 1 1 2 2 2 0 DoxX-like family TRAP_beta PF05753.14 RUS68749.1 - 0.095 12.1 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) PEARLI-4 PF05278.12 RUS68750.1 - 0.038 13.6 2.0 0.047 13.3 2.0 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) FlaG PF03646.15 RUS68750.1 - 0.043 14.0 2.1 0.06 13.5 2.1 1.2 1 0 0 1 1 1 0 FlaG protein DUF4023 PF13215.6 RUS68750.1 - 0.053 13.5 4.3 0.11 12.5 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4023) 7tm_1 PF00001.21 RUS68752.1 - 2.3e-13 50.1 17.8 4.1e-13 49.3 17.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS68752.1 - 1.9e-09 37.2 3.1 1.9e-09 37.2 3.1 3.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS68752.1 - 0.002 17.8 16.4 0.002 17.8 16.4 3.6 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS68752.1 - 0.033 13.6 21.8 0.31 10.4 21.8 2.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx zf-ribbon_3 PF13248.6 RUS68754.1 - 0.00032 20.0 18.4 50 3.5 0.1 9.7 3 2 9 12 12 12 8 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 RUS68754.1 - 0.071 13.0 14.9 13 5.8 0.2 7.8 2 1 6 8 8 8 0 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.17 RUS68754.1 - 7.9 6.3 28.2 23 4.8 1.9 5.0 1 1 4 5 5 5 0 Ribosomal protein S27 MFS_1 PF07690.16 RUS68755.1 - 2.4e-10 39.9 14.9 2.5e-10 39.8 14.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS68755.1 - 1.6e-08 33.9 10.1 1.8e-08 33.7 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter FGGY_N PF00370.21 RUS68756.1 - 6.8e-29 101.2 0.0 2.9e-28 99.1 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 RUS68756.1 - 0.0035 16.9 0.0 0.0045 16.5 0.0 1.6 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family rve PF00665.26 RUS68758.1 - 7.3e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1918 PF08940.11 RUS68758.1 - 0.25 11.0 0.8 0.54 9.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) MCU PF04678.13 RUS68760.1 - 7.6e-67 224.8 0.6 1e-66 224.4 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF1843 PF08898.10 RUS68760.1 - 0.0092 16.5 0.9 0.12 12.9 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) DUF4140 PF13600.6 RUS68760.1 - 0.06 13.8 0.8 12 6.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sulfatase PF00884.23 RUS68761.1 - 2e-68 231.1 0.6 2.6e-68 230.7 0.6 1.1 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 RUS68761.1 - 0.052 12.6 0.1 0.096 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PhyH PF05721.13 RUS68762.1 - 2e-08 34.8 0.0 2e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyoxalase PF00903.25 RUS68763.1 - 2e-21 76.5 0.0 4.6e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RUS68763.1 - 2.3e-07 31.1 0.0 6.6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 RUS68763.1 - 0.0011 19.7 0.0 0.0022 18.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Cyclophil_like PF04126.13 RUS68763.1 - 0.049 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like Glyoxalase_3 PF13468.6 RUS68763.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain LINES_N PF14694.6 RUS68764.1 - 8.3e-20 71.6 4.5 2e-19 70.3 4.5 1.7 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 RUS68764.1 - 1e-13 50.4 0.1 2.1e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Lines C-terminus F-box-like PF12937.7 RUS68766.1 - 8.7e-09 35.1 1.2 2.3e-08 33.8 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS68766.1 - 0.00012 21.9 1.3 0.00047 20.0 1.3 2.1 1 0 0 1 1 1 1 F-box domain ANTH PF07651.16 RUS68766.1 - 0.077 12.0 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 ANTH domain DUF3669 PF12417.8 RUS68767.1 - 0.17 12.1 2.6 6.2 7.1 0.0 4.3 5 0 0 5 5 5 0 Zinc finger protein DUF3757 PF12582.8 RUS68767.1 - 4.4 7.8 6.5 71 3.9 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3757) RVT_1 PF00078.27 RUS68768.1 - 0.021 14.4 1.1 0.082 12.4 0.0 2.2 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ERK-JNK_inhib PF15002.6 RUS68768.1 - 0.04 13.6 0.2 0.069 12.8 0.2 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor RVT_1 PF00078.27 RUS68769.1 - 3.7e-14 52.8 0.0 4.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fibrinogen_C PF00147.18 RUS68769.1 - 6.8e-12 45.7 0.4 1.1e-11 45.0 0.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Tim54 PF11711.8 RUS68769.1 - 0.082 11.7 0.1 0.096 11.5 0.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 fn3 PF00041.21 RUS68771.1 - 8.9e-14 51.6 0.1 1.3e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS68771.1 - 4.7e-05 23.9 0.2 9.1e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RUS68771.1 - 0.0015 18.8 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) NAR2 PF16974.5 RUS68771.1 - 0.077 12.4 0.1 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 High-affinity nitrate transporter accessory Interfer-bind PF09294.10 RUS68771.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF4148 PF13663.6 RUS68772.1 - 3e-09 36.9 0.0 0.13 12.4 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF4148) PepSY_2 PF13670.6 RUS68772.1 - 5.4e-05 23.1 21.9 0.2 11.7 2.3 4.4 4 0 0 4 4 4 4 Peptidase propeptide and YPEB domain ACC_epsilon PF13822.6 RUS68772.1 - 0.04 14.6 29.8 3.2 8.5 2.9 4.2 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit RXLR PF16810.5 RUS68772.1 - 0.44 11.0 4.9 4.5 7.7 0.0 3.5 4 0 0 4 4 4 0 RXLR phytopathogen effector protein, Avirulence activity ETRAMP PF09716.10 RUS68772.1 - 0.54 10.4 11.4 3.5 7.8 0.0 4.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 RUS68773.1 - 1.3e-16 60.8 0.0 1.4e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS68773.1 - 7.1e-12 45.1 0.0 8.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS68773.1 - 0.032 14.2 0.5 0.041 13.8 0.5 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RUS68773.1 - 0.043 13.5 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 RUS68773.1 - 0.079 12.3 0.1 0.099 12.0 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS68773.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase 7tm_1 PF00001.21 RUS68774.1 - 1.6e-23 83.4 11.2 1.6e-23 83.4 11.2 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 RUS68774.1 - 5.7e-07 29.2 1.5 0.037 13.8 0.3 3.6 2 1 1 3 3 3 3 Leucine rich repeat 7TM_GPCR_Srx PF10328.9 RUS68774.1 - 0.35 10.4 9.7 0.39 10.3 7.5 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx RAI1 PF08652.11 RUS68775.1 - 0.0055 16.9 13.8 6 7.1 0.1 5.5 3 2 3 6 6 6 4 RAI1 like PD-(D/E)XK nuclease Caenor_Her-1 PF09232.10 RUS68777.1 - 0.0028 17.8 1.4 1 9.5 0.2 2.3 2 0 0 2 2 2 2 Caenorhabditis elegans Her-1 DUF1571 PF07608.11 RUS68777.1 - 0.05 13.0 0.6 0.47 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) GXWXG PF14231.6 RUS68777.1 - 0.053 13.6 0.5 17 5.6 0.1 2.5 2 0 0 2 2 2 0 GXWXG protein TPR_6 PF13174.6 RUS68777.1 - 0.054 14.1 0.1 28 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L44 PF00935.19 RUS68777.1 - 0.067 13.7 0.6 0.067 13.7 0.6 2.7 2 1 0 2 2 2 0 Ribosomal protein L44 OrfB_IS605 PF01385.19 RUS68777.1 - 0.068 13.4 4.0 0.96 9.7 0.6 2.4 2 0 0 2 2 2 0 Probable transposase CTD_bind PF04818.13 RUS68777.1 - 0.3 11.9 2.7 64 4.5 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase II-binding domain. ING PF12998.7 RUS68777.1 - 1.8 9.2 5.3 3.7 8.2 0.3 2.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding LMBR1 PF04791.16 RUS68777.1 - 4 6.3 6.3 77 2.0 6.0 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein HypA PF01155.19 RUS68778.1 - 0.15 12.1 0.5 0.35 10.9 0.5 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EGF PF00008.27 RUS68782.1 - 4.5e-07 30.0 21.5 0.00084 19.6 6.2 2.5 2 0 0 2 2 2 2 EGF-like domain Orf78 PF06024.12 RUS68782.1 - 0.02 15.2 0.0 0.079 13.3 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) EGF_3 PF12947.7 RUS68782.1 - 0.024 14.8 18.3 0.4 10.9 7.7 2.4 2 0 0 2 2 2 0 EGF domain EphA2_TM PF14575.6 RUS68782.1 - 0.078 13.9 0.0 0.23 12.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.15 RUS68782.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Otopetrin PF03189.13 RUS68782.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Otopetrin Adeno_E3_CR2 PF02439.15 RUS68782.1 - 0.97 9.2 3.9 1.5 8.6 3.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cytomega_TRL10 PF06084.11 RUS68782.1 - 1 9.4 5.9 0.25 11.4 0.7 2.5 1 1 1 2 2 2 0 Cytomegalovirus TRL10 protein GIDA PF01134.22 RUS68783.1 - 3.7e-165 549.8 0.0 5.4e-165 549.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 RUS68783.1 - 1.7e-73 247.3 0.1 2.5e-73 246.8 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 RUS68783.1 - 7.9e-08 32.1 2.9 1.4e-07 31.2 2.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS68783.1 - 4.5e-06 26.0 3.4 0.00036 19.7 1.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RUS68783.1 - 6.1e-06 25.7 0.4 1.1e-05 24.9 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS68783.1 - 0.00099 17.9 2.6 0.0046 15.7 0.3 2.7 3 0 0 3 3 3 1 HI0933-like protein HRDC PF00570.23 RUS68783.1 - 0.0012 18.8 0.1 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 HRDC domain Pyr_redox_3 PF13738.6 RUS68783.1 - 0.0017 17.6 0.3 0.032 13.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RUS68783.1 - 0.0031 16.8 0.4 0.0059 15.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 RUS68783.1 - 0.0085 16.6 0.3 0.028 15.0 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RUS68783.1 - 0.01 15.5 0.9 1.5 8.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RUS68783.1 - 0.051 13.8 0.9 0.19 12.0 0.9 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS68783.1 - 0.16 11.2 1.6 0.8 8.9 1.6 2.1 1 1 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 RUS68783.1 - 0.45 10.5 2.0 1 9.3 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rib_5-P_isom_A PF06026.14 RUS68784.1 - 6.8e-57 191.8 0.5 8.1e-57 191.6 0.5 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 RUS68784.1 - 1.1e-05 25.4 0.9 5.7e-05 23.1 0.2 2.2 1 1 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 RUS68784.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain adh_short_C2 PF13561.6 RUS68785.1 - 2.8e-55 187.5 1.0 3.3e-55 187.2 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS68785.1 - 1.2e-43 148.8 1.9 1.5e-43 148.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS68785.1 - 1.3e-07 31.7 1.7 2.2e-07 30.9 1.7 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS68785.1 - 1.8e-05 24.1 0.1 6.9e-05 22.2 0.0 2.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 RUS68785.1 - 0.00046 19.7 0.2 0.0011 18.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 RUS68785.1 - 0.0067 15.9 0.4 0.011 15.2 0.4 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.8 RUS68785.1 - 0.041 13.6 0.4 0.099 12.4 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 RUS68785.1 - 0.045 14.0 0.2 0.088 13.1 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 RUS68785.1 - 0.069 13.2 0.2 0.49 10.4 0.1 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 RUS68785.1 - 0.073 12.4 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 RUS68785.1 - 0.074 12.9 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 RUS68785.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SDA1 PF05285.12 RUS68787.1 - 0.0092 15.4 43.2 0.012 15.0 43.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS68787.1 - 0.49 8.5 44.1 0.63 8.2 44.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 RUS68787.1 - 3.1 7.9 9.4 5.3 7.1 9.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 7tm_1 PF00001.21 RUS68788.1 - 6e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS68788.1 - 1.3e-05 24.6 1.2 1.9e-05 24.1 1.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS68788.1 - 0.67 9.3 5.4 0.084 12.2 1.3 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx AA_permease_2 PF13520.6 RUS68789.1 - 2.8e-45 154.9 25.3 3.4e-45 154.6 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS68789.1 - 3.3e-19 68.8 17.9 3.3e-19 68.8 17.9 1.5 1 1 0 1 1 1 1 Amino acid permease COX7C PF02935.16 RUS68789.1 - 0.27 11.5 3.1 1.5 9.1 3.1 2.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc AA_permease_2 PF13520.6 RUS68790.1 - 1.9e-14 53.4 11.0 2.2e-14 53.1 11.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS68790.1 - 4.2e-12 45.4 9.6 5e-12 45.2 9.6 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 RUS68790.1 - 0.0097 15.0 12.1 0.064 12.3 12.1 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3021 PF11457.8 RUS68790.1 - 0.045 14.1 5.7 0.041 14.2 4.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) EamA PF00892.20 RUS68790.1 - 0.048 13.8 6.5 0.11 12.6 0.8 2.2 1 1 0 2 2 2 0 EamA-like transporter family DUF2496 PF10689.9 RUS68791.1 - 0.047 13.5 3.5 83 3.1 0.0 6.2 4 2 4 8 8 8 0 Protein of unknown function (DUF2496) DUF3627 PF12299.8 RUS68791.1 - 0.71 10.0 9.5 3.6 7.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) ATP-cone PF03477.16 RUS68792.1 - 0.0065 17.0 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_lgC PF02867.15 RUS68793.1 - 2.8e-36 125.2 0.0 3.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 RUS68794.1 - 0.015 15.8 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 ATP cone domain zf-CCHC PF00098.23 RUS68795.1 - 9.4e-06 25.5 1.4 2.2e-05 24.3 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS68795.1 - 0.013 15.3 2.7 0.029 14.2 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68795.1 - 0.32 10.8 2.6 0.59 9.9 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle CSD PF00313.22 RUS68796.1 - 8e-19 67.3 0.0 1.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RUS68796.1 - 0.087 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain RVT_1 PF00078.27 RUS68798.1 - 1.5e-21 77.0 0.1 2.9e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Taxilin PF09728.9 RUS68799.1 - 0.031 13.5 7.2 0.042 13.0 7.2 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein MutS_V PF00488.21 RUS68800.1 - 6.3e-84 280.7 0.3 6.3e-84 280.7 0.3 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 RUS68800.1 - 8.7e-37 127.2 1.0 2.2e-36 125.9 1.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 RUS68800.1 - 1.2e-20 74.2 3.4 4.4e-19 69.1 0.0 3.3 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.18 RUS68800.1 - 6.2e-20 71.3 0.6 1.7e-19 69.9 0.6 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 RUS68800.1 - 2.3e-12 47.1 0.1 6.4e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 RUS68800.1 - 0.023 14.3 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 RUS68802.1 - 3.4e-12 46.1 28.4 0.0013 19.1 3.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS68802.1 - 6.7e-12 45.2 26.7 0.0015 19.2 1.0 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS68802.1 - 4.9e-08 33.1 25.2 0.002 18.4 0.0 4.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RUS68802.1 - 0.00094 19.4 16.8 0.053 13.7 6.5 3.2 2 1 1 3 3 3 2 Aberrant zinc-finger zf_C2H2_10 PF18414.1 RUS68802.1 - 0.049 13.2 1.5 0.11 12.0 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-H2C2_5 PF13909.6 RUS68802.1 - 0.14 11.9 9.4 3.1 7.6 1.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 RUS68802.1 - 0.66 10.6 18.5 2.5 8.8 6.3 4.0 2 1 1 3 3 3 0 FOXP coiled-coil domain Sina PF03145.16 RUS68802.1 - 3.2 7.7 22.2 0.31 11.0 10.9 2.2 1 1 1 2 2 2 0 Seven in absentia protein family BSMAP PF12280.8 RUS68803.1 - 3.7e-06 27.3 0.0 5.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF1939 PF09154.10 RUS68803.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Caveolin PF01146.17 RUS68804.1 - 4.2e-44 149.7 1.0 4.9e-44 149.5 1.0 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 RUS68805.1 - 1.1e-41 142.0 0.0 1.2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Caveolin FERM_M PF00373.18 RUS68806.1 - 4.1e-11 43.3 0.0 7.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS68806.1 - 0.00049 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain Ocnus PF05005.15 RUS68807.1 - 3.5e-23 81.8 0.0 2.5e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Janus/Ocnus family (Ocnus) adh_short PF00106.25 RUS68808.1 - 1.9e-50 171.1 4.2 2.1e-50 170.9 4.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS68808.1 - 7.2e-41 140.3 2.9 8.1e-41 140.1 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS68808.1 - 3.4e-14 53.2 4.4 4.1e-14 52.9 4.4 1.0 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 RUS68808.1 - 0.00036 20.8 0.8 0.00041 20.6 0.8 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RUS68808.1 - 0.0026 17.3 1.5 0.0046 16.4 1.5 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 RUS68808.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DAGAT PF03982.13 RUS68808.1 - 0.057 12.3 0.6 0.093 11.6 0.5 1.3 1 1 0 1 1 1 0 Diacylglycerol acyltransferase FAD_binding_6 PF00970.24 RUS68809.1 - 2e-13 50.6 0.0 2.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 RUS68809.1 - 0.0011 19.2 0.0 0.0035 17.5 0.0 1.8 1 1 1 2 2 2 1 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.21 RUS68809.1 - 0.021 15.5 0.0 0.032 14.9 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.6 RUS68810.1 - 2.5e-32 112.3 41.7 2.8e-32 112.1 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS68810.1 - 7.1e-08 31.5 41.1 8.1e-08 31.3 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease K_trans PF02705.16 RUS68810.1 - 0.00019 20.1 11.7 0.00019 20.1 11.7 2.5 2 1 0 2 2 2 1 K+ potassium transporter Fibrinogen_C PF00147.18 RUS68811.1 - 5.8e-19 68.8 0.5 6.3e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain RVT_1 PF00078.27 RUS68812.1 - 1.3e-08 34.6 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_IV PF05190.18 RUS68812.1 - 0.097 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV Carn_acyltransf PF00755.20 RUS68813.1 - 3.4e-11 42.5 0.5 4.8e-11 42.0 0.1 1.4 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase DUF2458 PF10454.9 RUS68813.1 - 0.038 13.6 0.1 0.042 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Copine PF07002.16 RUS68814.1 - 2.4e-86 288.7 0.0 2.9e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RUS68814.1 - 5e-05 23.5 0.0 0.00011 22.3 0.0 1.5 1 1 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 RUS68814.1 - 0.0052 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4733 PF15878.5 RUS68814.1 - 0.027 14.9 0.7 0.05 14.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) Aconitase PF00330.20 RUS68815.1 - 5.2e-172 573.0 0.0 6.7e-172 572.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RUS68815.1 - 4.6e-45 153.2 0.0 9e-45 152.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain tRNA-synt_1c PF00749.21 RUS68816.1 - 1.9e-110 368.7 0.0 2.1e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ATP-synt_ab PF00006.25 RUS68817.1 - 1.8e-65 220.6 0.0 2.6e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 RUS68817.1 - 0.00047 20.0 0.8 0.0016 18.2 0.8 1.9 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 RUS68817.1 - 0.0099 16.3 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 RUS68817.1 - 0.015 15.7 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 RUS68817.1 - 0.05 13.9 0.6 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RUS68817.1 - 0.072 12.8 0.6 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RUS68817.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 RUS68817.1 - 0.1 12.1 0.2 0.27 10.7 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 RUS68817.1 - 0.12 11.6 0.2 0.56 9.4 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 RUS68817.1 - 0.13 11.2 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 RUS68817.1 - 0.17 11.2 0.3 0.3 10.4 0.3 1.4 1 0 0 1 1 1 0 KaiC ATP-synt PF00231.19 RUS68818.1 - 5.9e-74 249.3 2.7 6.6e-74 249.1 2.7 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 RUS68819.1 - 3.6e-74 249.0 0.1 5.1e-74 248.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RUS68819.1 - 1.2e-41 142.0 0.6 1.8e-41 141.4 0.6 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RUS68819.1 - 3e-05 24.5 0.0 7.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 RUS68819.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaJ PF00226.31 RUS68820.1 - 2.2e-27 94.9 2.9 3.3e-27 94.4 2.9 1.3 1 0 0 1 1 1 1 DnaJ domain Lamprin PF06403.11 RUS68820.1 - 0.01 15.8 4.2 0.017 15.1 3.4 1.7 1 1 1 2 2 2 0 Lamprin DUF3461 PF11944.8 RUS68821.1 - 0.17 12.0 1.8 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) OAD_gamma PF04277.13 RUS68821.1 - 1.8 9.2 4.0 4.5 7.9 3.5 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GREB1 PF15782.5 RUS68821.1 - 6 3.8 8.3 7.3 3.6 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CABIT PF12736.7 RUS68822.1 - 0.048 12.9 0.0 7.2 5.8 0.0 2.1 1 1 1 2 2 2 0 Cell-cycle sustaining, positive selection, tRNA-synt_2 PF00152.20 RUS68823.1 - 2.4e-63 214.1 0.0 2e-40 138.8 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) GAD PF02938.14 RUS68823.1 - 6.4e-27 93.6 0.1 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 RUS68823.1 - 0.089 12.3 0.1 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ABC_tran PF00005.27 RUS68824.1 - 3.2e-33 115.1 0.0 3.7e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS68824.1 - 1.8e-06 28.0 0.8 0.00037 20.4 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS68824.1 - 1.2e-05 24.9 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS68824.1 - 0.00039 20.4 0.1 0.00058 19.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RUS68824.1 - 0.0008 19.8 0.0 0.00086 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RUS68824.1 - 0.0015 19.1 0.0 0.0016 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RUS68824.1 - 0.0017 18.4 0.1 0.072 13.2 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 RUS68824.1 - 0.0064 16.4 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 RUS68824.1 - 0.013 15.2 0.0 0.013 15.2 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS68824.1 - 0.024 14.9 0.1 0.029 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 RUS68824.1 - 0.04 14.0 0.3 0.063 13.4 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 RUS68824.1 - 0.042 14.4 0.1 0.043 14.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RUS68824.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS68824.1 - 0.081 13.3 0.0 0.34 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RUS68824.1 - 0.087 12.4 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RUS68824.1 - 0.11 11.9 0.0 0.22 10.9 0.1 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 RUS68824.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 RUS68824.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 RUS68824.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ATPase_2 PF01637.18 RUS68824.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CbiA PF01656.23 RUS68824.1 - 0.2 11.7 0.2 0.39 10.8 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_25 PF13649.6 RUS68825.1 - 0.0014 19.3 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS68825.1 - 0.0045 17.6 0.0 0.012 16.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS68826.1 - 1.7e-12 47.8 0.0 3.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS68826.1 - 9.5e-11 42.3 0.1 1.9e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS68826.1 - 7e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RUS68826.1 - 4.3e-05 23.3 0.0 0.0001 22.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS68826.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 RUS68826.1 - 0.022 13.3 0.0 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 RUS68827.1 - 4e-10 40.2 0.0 7.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS68827.1 - 5.2e-07 30.3 0.0 8.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS68827.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 RUS68827.1 - 0.031 12.9 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SDA1 PF05285.12 RUS68827.1 - 3.5 6.9 26.9 4.6 6.6 26.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RUS68827.1 - 8.8 5.5 23.4 10 5.3 23.4 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_L15e PF00827.17 RUS68828.1 - 4.9e-66 222.1 0.3 6.2e-66 221.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSS PF03034.15 RUS68829.1 - 2.7e-113 378.3 13.9 3.6e-113 377.9 13.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase NodZ PF05830.11 RUS68830.1 - 0.032 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) NYN PF01936.18 RUS68830.1 - 0.041 14.4 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 NYN domain CUB PF00431.20 RUS68831.1 - 3.3e-35 120.8 0.0 3e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 CUB domain Tetraspanin PF00335.20 RUS68831.1 - 0.016 14.9 0.3 0.017 14.8 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family zf-H2C2_2 PF13465.6 RUS68832.1 - 7.7e-71 231.6 114.3 1.3e-08 34.9 2.9 13.4 14 0 0 14 14 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 RUS68832.1 - 1.5e-52 173.2 101.3 2.5e-06 27.6 1.5 12.4 12 0 0 12 12 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS68832.1 - 2.3e-29 99.5 94.0 0.00045 20.8 1.2 12.5 12 0 0 12 12 11 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS68832.1 - 9.1e-19 67.2 46.7 0.015 15.6 0.1 11.8 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS68832.1 - 2.1e-16 59.5 94.1 3.5e-05 23.7 1.3 12.7 11 2 0 11 11 10 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS68832.1 - 9.7e-11 41.2 16.9 0.8 9.5 0.1 8.1 7 0 0 7 7 7 4 zinc-finger C2H2-type zf-met PF12874.7 RUS68832.1 - 3.1e-10 40.1 68.7 0.16 12.4 0.6 12.2 11 1 0 11 11 11 7 Zinc-finger of C2H2 type C1_1 PF00130.22 RUS68832.1 - 8.3e-09 35.2 38.9 0.24 11.3 0.1 9.4 6 2 4 10 10 9 6 Phorbol esters/diacylglycerol binding domain (C1 domain) SET PF00856.28 RUS68832.1 - 1.8e-07 31.7 3.6 6.1e-06 26.7 0.2 3.1 2 1 0 2 2 2 1 SET domain zf-H2C2_5 PF13909.6 RUS68832.1 - 5.9e-06 25.9 36.8 0.0012 18.6 7.3 11.6 11 6 0 11 11 9 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 RUS68832.1 - 1.5e-05 24.7 23.4 4.5 7.3 0.0 8.0 7 0 0 7 7 7 1 zinc-finger of a C2HC-type zf_PR_Knuckle PF18445.1 RUS68832.1 - 4.5e-05 23.2 0.2 0.00026 20.7 0.2 2.4 1 0 0 1 1 1 1 PR zinc knuckle motif zf_UBZ PF18439.1 RUS68832.1 - 7.1e-05 22.3 40.4 1.7 8.3 0.0 9.7 11 0 0 11 11 10 5 Ubiquitin-Binding Zinc Finger BolA PF01722.18 RUS68832.1 - 0.00011 22.3 16.8 3.1 8.2 0.4 6.4 3 2 2 5 5 4 3 BolA-like protein Zn-ribbon_8 PF09723.10 RUS68832.1 - 0.0011 19.0 46.3 0.12 12.5 2.2 8.0 5 2 4 9 9 8 6 Zinc ribbon domain DUF4428 PF14471.6 RUS68832.1 - 0.0019 18.1 39.6 0.0055 16.6 1.3 7.5 4 2 2 6 6 6 1 Domain of unknown function (DUF4428) Arc_trans_TRASH PF08394.10 RUS68832.1 - 0.0025 18.1 11.9 10 6.6 0.0 7.7 7 0 0 7 7 7 0 Archaeal TRASH domain DUF3268 PF11672.8 RUS68832.1 - 0.0049 17.2 30.9 0.38 11.1 0.4 5.6 5 0 0 5 5 5 3 zinc-finger-containing domain zf-C2H2_3rep PF18868.1 RUS68832.1 - 0.036 14.7 42.9 0.099 13.3 0.8 8.6 2 1 6 8 8 8 0 Zinc finger C2H2-type, 3 repeats C1_2 PF03107.16 RUS68832.1 - 0.13 12.6 75.8 2.6 8.4 7.2 10.3 3 1 5 8 8 8 0 C1 domain C1-set PF07654.15 RUS68832.1 - 1.2 9.6 33.7 20 5.6 0.1 9.2 1 1 9 10 10 10 0 Immunoglobulin C1-set domain zinc_ribbon_15 PF17032.5 RUS68832.1 - 1.8 9.4 58.0 0.55 11.0 2.8 7.7 2 1 5 8 8 8 0 zinc-ribbon family Desulfoferrod_N PF06397.12 RUS68832.1 - 9.2 6.0 51.2 8.3 6.1 0.3 10.0 10 0 0 10 10 10 0 Desulfoferrodoxin, N-terminal domain UPF0128 PF03673.13 RUS68833.1 - 0.013 15.0 0.1 57 3.1 0.0 4.5 1 1 5 6 6 6 0 Uncharacterised protein family (UPF0128) Zds_C PF08632.10 RUS68833.1 - 0.047 13.5 11.2 6.5 6.6 0.1 5.4 6 0 0 6 6 6 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF3644 PF12358.8 RUS68833.1 - 0.24 11.9 1.7 80 3.8 0.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3644) DUF4590 PF15257.6 RUS68834.1 - 0.02 14.8 6.2 0.33 10.9 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4590) Oxidored_q4 PF00507.19 RUS68835.1 - 1.3e-31 108.7 0.9 1.3e-31 108.7 0.9 1.8 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Oxidored_q6 PF01058.22 RUS68836.1 - 2.1e-23 82.6 0.2 2.6e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_51K PF01512.17 RUS68837.1 - 3.9e-46 156.7 0.0 5.3e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 RUS68837.1 - 2.1e-32 111.0 0.1 3.6e-32 110.3 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 RUS68837.1 - 8.3e-09 35.2 0.1 2e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 SLBB domain NADHdh PF00146.21 RUS68838.1 - 4.2e-126 420.3 26.2 4.8e-126 420.1 26.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Proton_antipo_M PF00361.20 RUS68839.1 - 1.8e-82 276.8 30.7 3.2e-82 276.0 30.7 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 RUS68839.1 - 3.5e-18 65.4 5.0 3.5e-18 65.4 5.0 3.5 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 RUS68839.1 - 0.18 11.4 0.2 0.18 11.4 0.2 2.9 3 0 0 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Proton_antipo_M PF00361.20 RUS68840.1 - 1.6e-68 231.1 33.9 7.4e-68 228.9 33.9 1.9 1 1 0 1 1 1 1 Proton-conducting membrane transporter DUF2273 PF10031.9 RUS68840.1 - 0.0055 16.7 0.7 0.0055 16.7 0.7 5.1 7 0 0 7 7 7 1 Small integral membrane protein (DUF2273) Proton_antipo_M PF00361.20 RUS68841.1 - 6.3e-70 235.7 30.1 7.9e-70 235.4 30.1 1.1 1 0 0 1 1 1 1 Proton-conducting membrane transporter Sulfatase PF00884.23 RUS68842.1 - 2e-34 119.4 0.0 2.5e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 RUS68842.1 - 0.00039 20.3 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 RUS68842.1 - 0.0017 18.6 0.4 0.012 15.9 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 RUS68842.1 - 0.003 18.3 0.1 0.025 15.3 0.1 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase 7tm_1 PF00001.21 RUS68843.1 - 2.6e-06 27.0 10.3 2.6e-06 27.0 10.3 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS68843.1 - 0.019 14.6 25.0 0.0059 16.3 21.2 2.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF5596 PF18082.1 RUS68843.1 - 0.093 12.6 0.0 0.38 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) ABC_tran PF00005.27 RUS68844.1 - 0.0016 18.9 0.0 0.23 12.0 0.0 2.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 RUS68844.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mur_ligase_M PF08245.12 RUS68845.1 - 4.6e-21 75.7 1.6 1.1e-20 74.5 1.6 1.7 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RUS68845.1 - 2e-10 40.8 0.1 8.9e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain RimK PF08443.11 RUS68845.1 - 8e-08 32.1 0.1 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 RUS68845.1 - 8.5e-06 25.4 0.1 2.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 RUS68845.1 - 0.0002 20.9 0.4 0.011 15.3 0.1 3.0 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus GSH-S_ATP PF02955.16 RUS68845.1 - 0.00021 20.8 0.0 0.00048 19.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain DUF1910 PF08928.10 RUS68845.1 - 0.026 14.5 0.3 0.06 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) T2SSE PF00437.20 RUS68846.1 - 2.3e-83 279.4 0.3 3.5e-83 278.8 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 RUS68846.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS68846.1 - 0.0044 17.3 0.7 0.013 15.7 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS68846.1 - 0.0046 16.8 0.5 0.01 15.6 0.3 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 RUS68846.1 - 0.005 16.3 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 RUS68846.1 - 0.0052 16.8 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RUS68846.1 - 0.0074 16.7 0.1 0.015 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 RUS68846.1 - 0.0087 15.6 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 RUS68846.1 - 0.011 16.1 0.5 0.023 15.1 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RUS68846.1 - 0.012 16.1 2.2 0.024 15.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 RUS68846.1 - 0.022 14.5 0.2 0.071 12.9 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 RUS68846.1 - 0.024 14.4 0.6 0.044 13.5 0.4 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 RUS68846.1 - 0.084 12.2 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SDH_alpha PF03313.15 RUS68847.1 - 2.4e-90 302.7 2.9 3.2e-90 302.3 2.9 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 RUS68847.1 - 3.8e-21 76.1 0.0 8.4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain zf-C2H2 PF00096.26 RUS68848.1 - 7.5e-79 256.0 132.7 1.3e-06 28.5 0.4 16.3 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS68848.1 - 2.2e-58 192.2 148.3 9.4e-06 25.8 3.0 16.3 17 0 0 17 17 16 15 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS68848.1 - 2.8e-52 170.8 125.4 0.0016 19.1 0.5 16.2 16 0 0 16 16 16 15 C2H2-type zinc finger zf-met PF12874.7 RUS68848.1 - 3.4e-16 59.0 109.5 0.23 11.9 0.4 15.3 15 0 0 15 15 15 12 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS68848.1 - 1.9e-15 56.3 78.7 0.014 15.2 0.0 14.6 15 0 0 15 15 15 8 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RUS68848.1 - 3.5e-11 43.3 74.6 0.00045 20.5 4.1 8.1 1 1 8 9 9 9 7 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 RUS68848.1 - 4.8e-09 36.2 81.2 0.017 15.2 3.5 11.9 6 4 9 15 15 15 6 Zinc ribbon domain zf_UBZ PF18439.1 RUS68848.1 - 6.8e-09 35.2 70.1 1 9.0 0.2 14.7 15 0 0 15 15 15 7 Ubiquitin-Binding Zinc Finger LIM PF00412.22 RUS68848.1 - 1.8e-05 24.9 93.5 0.084 13.1 2.8 11.4 4 3 8 12 12 12 5 LIM domain ADK_lid PF05191.14 RUS68848.1 - 2.7e-05 24.1 46.7 0.19 11.8 0.5 8.7 6 2 2 8 8 8 4 Adenylate kinase, active site lid zf-Di19 PF05605.12 RUS68848.1 - 0.00084 19.6 6.5 0.00084 19.6 6.5 9.3 5 2 4 10 10 10 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RUS68848.1 - 0.009 16.0 12.2 0.013 15.5 3.5 17.1 16 2 0 16 16 14 5 C2H2-type zinc finger DUF2944 PF11161.8 RUS68848.1 - 0.015 15.2 0.9 39 4.1 0.0 4.4 3 2 1 5 5 5 0 Protein of unknown function (DUF2946) zf-C2HE PF16278.5 RUS68848.1 - 0.036 14.5 124.0 0.16 12.4 6.1 13.9 2 2 13 15 15 15 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 RUS68848.1 - 0.18 12.6 80.9 0.73 10.6 4.0 8.6 1 1 8 9 9 9 0 zinc-ribbon family C1_4 PF07975.12 RUS68848.1 - 0.29 11.4 95.8 0.52 10.6 3.3 10.9 3 3 8 12 12 12 0 TFIIH C1-like domain zf-trcl PF13451.6 RUS68848.1 - 5.8 6.9 101.9 1.9 8.4 0.2 14.3 11 3 3 14 14 14 0 Probable zinc-ribbon domain MBD PF01429.19 RUS68848.1 - 9.7 6.0 10.6 2e+02 1.7 0.9 6.0 4 2 0 4 4 4 0 Methyl-CpG binding domain Fibrinogen_C PF00147.18 RUS68849.1 - 3.7e-40 138.1 0.9 4.5e-40 137.8 0.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Vanabin-2 PF11437.8 RUS68850.1 - 2.6 8.2 32.2 5.5e+02 0.8 32.2 2.5 1 1 0 1 1 1 0 Vanadium-binding protein 2 CSD PF00313.22 RUS68852.1 - 7e-20 70.7 0.0 1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RUS68852.1 - 0.0017 18.0 0.5 0.0052 16.4 0.5 1.8 1 1 0 1 1 1 1 Ribonuclease B OB domain DUF3456 PF11938.8 RUS68853.1 - 8.6e-28 97.8 6.9 8.6e-28 97.8 6.9 1.9 2 1 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP DLP_helical PF18709.1 RUS68853.1 - 0.002 17.4 0.3 0.0034 16.6 0.2 1.4 2 0 0 2 2 2 1 Dynamin-like helical domain SapB_1 PF05184.15 RUS68853.1 - 0.051 13.6 2.5 0.98 9.5 0.2 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF4820 PF16091.5 RUS68853.1 - 1.1 8.6 6.6 12 5.2 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 RUS68853.1 - 1.1 7.4 11.8 1.5 7.0 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein CAF1A PF12253.8 RUS68853.1 - 3.4 7.9 16.8 7.5 6.8 16.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A EF-hand_1 PF00036.32 RUS68854.1 - 1.4e-20 71.2 0.4 6.2e-08 31.6 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS68854.1 - 1.3e-17 64.0 1.6 1.2e-07 32.1 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS68854.1 - 5.2e-17 61.4 1.1 1.6e-10 40.7 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS68854.1 - 7.5e-17 60.0 0.5 5.2e-08 32.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS68854.1 - 3.9e-14 51.3 0.1 1.1e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS68854.1 - 0.00015 22.1 0.0 0.00018 21.8 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RUS68854.1 - 0.0018 18.4 0.2 0.14 12.4 0.0 2.1 1 1 1 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 RUS68854.1 - 0.022 14.7 0.1 0.25 11.2 0.0 2.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 RUS68854.1 - 0.03 15.2 0.0 0.038 14.9 0.0 1.2 1 1 0 1 1 1 0 EF-hand domain CCD48 PF15799.5 RUS68854.1 - 0.062 11.6 0.0 0.065 11.5 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Cyanate_lyase PF02560.14 RUS68854.1 - 0.072 12.9 0.4 0.17 11.7 0.1 1.8 1 1 1 2 2 2 0 Cyanate lyase C-terminal domain Ras PF00071.22 RUS68855.1 - 2.2e-09 37.1 0.0 3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Bac_globin PF01152.21 RUS68855.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin zf-C2H2 PF00096.26 RUS68858.1 - 0.033 14.6 2.9 2.8 8.5 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS68858.1 - 0.051 14.4 4.6 2 9.5 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_S2 PF00318.20 RUS68858.1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.7 2 1 0 2 2 2 0 Ribosomal protein S2 ALMT PF11744.8 RUS68858.1 - 0.91 8.3 20.7 1.3 7.7 20.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5401 PF17380.2 RUS68858.1 - 2.4 6.1 27.3 3.8 5.5 27.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DDE_Tnp_4 PF13359.6 RUS68859.1 - 9.5e-33 113.1 0.0 1.7e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS68859.1 - 1.2e-14 54.4 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS68859.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain MADF_DNA_bdg PF10545.9 RUS68860.1 - 2.4e-16 59.8 4.4 4.5e-16 58.9 4.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 RUS68860.1 - 0.014 15.8 2.7 0.023 15.0 2.7 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-CCHC_5 PF14787.6 RUS68861.1 - 0.0099 15.6 3.8 0.022 14.5 3.8 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 RUS68861.1 - 0.042 14.1 0.2 0.18 12.1 0.1 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Fibrinogen_C PF00147.18 RUS68862.1 - 7.7e-25 88.0 2.3 8.9e-25 87.8 2.3 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Metallophos PF00149.28 RUS68863.1 - 9.9e-19 68.6 1.2 1.8e-18 67.8 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 RUS68863.1 - 3.7e-15 56.3 0.2 1.2e-14 54.6 0.1 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 RUS68863.1 - 1.4e-08 35.4 0.2 5e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 RUS68863.1 - 0.0037 17.5 0.1 0.043 14.0 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 RUS68863.1 - 0.0058 17.1 0.0 0.024 15.1 0.0 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 RUS68863.1 - 0.054 13.8 0.1 0.19 12.1 0.1 2.0 1 0 0 1 1 1 0 Fibronectin type III domain PhoD PF09423.10 RUS68863.1 - 0.31 10.0 3.2 3.6 6.5 0.0 2.5 1 1 0 2 2 2 0 PhoD-like phosphatase PUB PF09409.10 RUS68864.1 - 6.2e-24 83.7 0.3 1.2e-23 82.9 0.3 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 RUS68864.1 - 5.8e-09 36.0 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain CK_II_beta PF01214.18 RUS68865.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Peptidase_M16 PF00675.20 RUS68868.1 - 4.4e-42 143.6 0.0 6.5e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RUS68868.1 - 3.2e-18 66.4 0.0 8e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 RUS68868.1 - 1.4e-13 50.8 0.1 2e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 ydhR PF08803.11 RUS68868.1 - 0.052 13.5 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR SDA1 PF05285.12 RUS68870.1 - 0.02 14.3 56.2 0.031 13.7 56.2 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_I_A49 PF06870.12 RUS68870.1 - 0.035 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Gal-bind_lectin PF00337.22 RUS68871.1 - 1.2e-25 89.6 0.6 1.4e-25 89.3 0.6 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin PNP_UDP_1 PF01048.20 RUS68872.1 - 9.3e-42 142.9 0.0 1.1e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NAD_binding_10 PF13460.6 RUS68872.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Myb_DNA-bind_4 PF13837.6 RUS68873.1 - 6.3e-13 48.9 0.8 6.3e-13 48.9 0.8 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RUS68873.1 - 0.0071 16.6 0.4 0.0071 16.6 0.4 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Ferritin PF00210.24 RUS68873.1 - 0.039 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain TraG_N PF07916.11 RUS68873.1 - 0.081 11.8 1.4 0.11 11.3 1.4 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Cmyb_C PF09316.10 RUS68873.1 - 0.41 10.3 6.6 0.057 13.1 2.4 1.7 2 0 0 2 2 2 0 C-myb, C-terminal DUF4441 PF14536.6 RUS68873.1 - 2.5 8.3 8.4 1.3 9.2 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Metallophos PF00149.28 RUS68874.1 - 0.02 15.4 0.2 0.035 14.6 0.1 1.4 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase SSF PF00474.17 RUS68875.1 - 8e-06 25.0 0.3 9.8e-06 24.7 0.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DEFB136 PF17333.2 RUS68876.1 - 8e-05 22.5 20.8 0.28 11.2 1.0 3.8 3 0 0 3 3 3 3 Beta defensin 136 DSL PF01414.19 RUS68876.1 - 3.1 8.1 63.3 1.7 8.9 16.4 3.4 3 0 0 3 3 3 0 Delta serrate ligand Med26 PF08711.11 RUS68877.1 - 1.4e-08 34.6 0.0 0.055 13.5 0.0 3.6 2 1 2 4 4 4 3 TFIIS helical bundle-like domain SH3_10 PF17902.1 RUS68877.1 - 0.0011 19.0 2.5 3.3 7.9 0.1 3.5 2 1 1 3 3 3 2 SH3 domain PQ-loop PF04193.14 RUS68877.1 - 0.0089 15.8 2.5 0.53 10.1 0.1 3.0 4 0 0 4 4 4 1 PQ loop repeat DUF5337 PF17272.2 RUS68877.1 - 0.021 14.6 0.3 3.4 7.6 0.0 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5337) DUF1899 PF08953.11 RUS68877.1 - 0.025 14.5 0.5 28 4.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1899) DUF5407 PF17401.2 RUS68877.1 - 0.08 13.2 0.0 1.1e+02 3.2 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5407) DUF1072 PF06380.11 RUS68877.1 - 2.5 8.0 13.9 7.5 6.5 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1072) LRR_4 PF12799.7 RUS68878.1 - 2.2e-15 56.5 28.1 0.0022 18.3 0.0 9.4 7 2 2 10 10 10 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 RUS68878.1 - 9.3e-09 35.1 0.2 3.1e-08 33.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 RUS68878.1 - 2e-07 30.5 39.3 0.092 12.8 0.0 12.1 14 0 0 14 14 14 2 Leucine Rich repeat F-box_5 PF18511.1 RUS68878.1 - 0.00041 19.9 0.1 0.001 18.6 0.1 1.7 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 RUS68878.1 - 0.0049 17.2 26.3 47 5.1 0.0 9.7 9 0 0 9 9 9 0 Leucine Rich Repeat F-box PF00646.33 RUS68878.1 - 0.0068 16.3 0.2 0.0068 16.3 0.2 3.2 3 0 0 3 3 3 1 F-box domain LRR_9 PF14580.6 RUS68878.1 - 0.12 11.9 0.4 0.52 9.8 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 RUS68878.1 - 0.28 11.0 21.8 1.6 8.6 0.2 7.4 8 1 0 8 8 8 0 Leucine rich repeat SAM_Ste50p PF09235.10 RUS68878.1 - 4 7.8 13.7 0.88 9.9 0.3 4.5 5 0 0 5 5 5 0 Ste50p, sterile alpha motif A2M_recep PF07677.14 RUS68879.1 - 4.5e-19 68.9 0.1 6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain TED_complement PF07678.14 RUS68880.1 - 9.9e-08 31.4 0.1 1.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain DUF1494 PF07379.11 RUS68880.1 - 0.0073 16.2 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1494) TED_complement PF07678.14 RUS68881.1 - 5e-39 134.2 0.1 5.9e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain Snf7 PF03357.21 RUS68883.1 - 1.6e-14 53.9 23.0 1.6e-14 53.9 23.0 1.7 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 RUS68883.1 - 1.3e-07 31.7 7.5 1.9e-07 31.1 7.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UCH PF00443.29 RUS68883.1 - 1.1 8.7 5.9 1.2 8.5 5.9 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 RUS68884.1 - 2.4e-56 188.3 1.7 1.9e-16 60.4 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS68884.1 - 2.5e-43 145.9 9.5 1.4e-08 35.1 0.0 5.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS68884.1 - 3.1e-35 119.7 7.1 2.9e-10 40.2 0.1 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS68884.1 - 1.3e-31 107.6 4.9 1.9e-07 31.2 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 RUS68884.1 - 3.1e-31 103.9 3.2 4e-06 26.7 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat DUF1843 PF08898.10 RUS68884.1 - 0.034 14.7 0.1 52 4.5 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF3447 PF11929.8 RUS68884.1 - 0.051 13.5 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) PRODH PF18327.1 RUS68884.1 - 0.2 11.9 0.1 8.5 6.7 0.1 3.2 3 1 1 4 4 4 0 Proline utilization A proline dehydrogenase N-terminal domain FR47 PF08445.10 RUS68885.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RUS68885.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS68885.1 - 0.003 18.0 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nop14 PF04147.12 RUS68885.1 - 0.032 12.5 20.0 0.038 12.2 20.0 1.0 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.25 RUS68885.1 - 0.033 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_pol_phi PF04931.13 RUS68885.1 - 0.33 9.0 41.0 0.44 8.6 41.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rhabdo_ncap PF00945.18 RUS68885.1 - 0.81 8.5 9.3 1.2 8.0 9.3 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CDC45 PF02724.14 RUS68885.1 - 0.88 7.8 21.0 1.2 7.4 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 RUS68885.1 - 0.93 8.5 17.3 1.4 7.9 17.3 1.2 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 RUS68885.1 - 1 8.7 22.1 1.3 8.4 22.1 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS68885.1 - 1.6 7.1 16.5 2.1 6.7 16.5 1.0 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 RUS68885.1 - 2.4 8.0 11.0 2.9 7.7 11.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2796 PF10986.8 RUS68885.1 - 2.4 8.1 6.9 3.8 7.4 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RRN3 PF05327.11 RUS68885.1 - 7.3 5.0 23.2 9 4.7 23.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 RUS68885.1 - 9.7 6.0 20.1 16 5.3 20.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Glyoxalase PF00903.25 RUS68886.1 - 2.3e-15 56.9 0.3 3.8e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RUS68886.1 - 9.2e-10 38.8 0.1 0.0024 18.1 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 RUS68886.1 - 7.5e-05 22.9 0.1 0.11 12.7 0.0 2.7 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 RUS68886.1 - 0.002 18.3 0.0 0.072 13.3 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal LIM PF00412.22 RUS68889.1 - 3.8e-21 75.1 22.4 3.1e-12 46.5 7.1 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS68889.1 - 9.5e-18 63.8 1.0 1.9e-17 62.8 1.0 1.6 1 0 0 1 1 1 1 Homeodomain TNFR_c6 PF00020.18 RUS68889.1 - 7.2 7.1 9.9 1.4 9.4 0.9 3.8 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Trigger_C PF05698.14 RUS68890.1 - 4e-26 92.0 11.6 4e-26 92.0 11.6 2.8 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 RUS68890.1 - 3.1e-15 56.3 0.6 1e-14 54.6 0.6 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Trigger_N PF05697.13 RUS68890.1 - 1.3e-11 45.0 0.7 1.3e-11 45.0 0.7 3.5 3 1 0 3 3 3 1 Bacterial trigger factor protein (TF) BLUF PF04940.12 RUS68890.1 - 0.051 13.7 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Sensors of blue-light using FAD CwsA PF10814.8 RUS68890.1 - 0.077 13.2 0.6 0.99 9.6 0.3 2.3 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF5340 PF17275.2 RUS68890.1 - 0.15 12.2 0.1 0.56 10.4 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Fib_alpha PF08702.10 RUS68890.1 - 0.21 11.7 9.3 0.09 13.0 4.0 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 RUS68890.1 - 0.49 10.6 6.6 0.41 10.9 1.8 2.7 3 0 0 3 3 2 0 Haemolysin XhlA zf-C4H2 PF10146.9 RUS68890.1 - 0.52 10.6 4.9 0.65 10.3 3.8 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Csm1_N PF18504.1 RUS68890.1 - 0.65 10.4 6.2 1.2 9.6 0.8 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2203 PF09969.9 RUS68890.1 - 1.1 10.1 7.4 1.7 9.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lon_C PF05362.13 RUS68891.1 - 2.6e-83 278.6 0.5 3.1e-83 278.4 0.5 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 RUS68891.1 - 2e-08 34.1 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase TRI12 PF06609.13 RUS68891.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) IPPT PF01715.17 RUS68892.1 - 2.8e-60 203.9 0.1 3.3e-60 203.7 0.1 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 RUS68892.1 - 1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase Cytidylate_kin PF02224.18 RUS68892.1 - 0.0031 17.3 0.1 0.0057 16.4 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase Hydin_ADK PF17213.3 RUS68892.1 - 0.0083 16.4 0.2 0.015 15.6 0.2 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA PF00004.29 RUS68892.1 - 0.023 15.1 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RUS68892.1 - 0.037 14.2 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 RUS68892.1 - 0.047 12.9 0.4 0.09 12.0 0.2 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 RUS68892.1 - 0.12 12.9 0.6 1.2 9.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain SCAN PF02023.17 RUS68894.1 - 7.7e-08 32.0 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 RUS68894.1 - 4.4e-06 26.5 3.4 0.00014 21.8 0.3 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS68894.1 - 0.0056 16.5 0.2 0.015 15.1 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle CUB PF00431.20 RUS68895.1 - 1.1e-57 193.1 0.0 5.5e-30 103.9 0.0 2.0 2 0 0 2 2 2 2 CUB domain Glyco_hydro_16 PF00722.21 RUS68895.1 - 0.038 13.5 0.3 6.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 FANCL_C PF11793.8 RUS68895.1 - 0.039 14.1 2.9 4.3 7.6 0.3 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 RUS68895.1 - 0.24 11.6 1.7 20 5.4 0.2 2.5 2 0 0 2 2 2 0 RING-variant domain CLN5 PF15014.6 RUS68897.1 - 8.1e-111 370.5 17.1 9.2e-109 363.7 17.1 2.0 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Hemopexin PF00045.19 RUS68897.1 - 0.046 13.7 2.2 0.11 12.5 2.2 1.6 1 0 0 1 1 1 0 Hemopexin Ank PF00023.30 RUS68898.1 - 4.7e-07 30.0 0.3 4.7e-07 30.0 0.3 2.7 3 0 0 3 3 3 1 Ankyrin repeat SOCS_box PF07525.16 RUS68898.1 - 2.9e-06 27.5 0.2 6.8e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 RUS68898.1 - 2.4e-05 24.5 0.1 6.4e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS68898.1 - 8.2e-05 22.7 1.5 0.0004 20.6 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 RUS68898.1 - 0.00054 20.5 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS68898.1 - 0.0019 18.7 0.0 0.005 17.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SAPS PF04499.15 RUS68900.1 - 0.94 8.2 7.3 1.3 7.7 7.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS68900.1 - 2.3 6.3 42.3 0.018 13.3 25.4 2.0 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 RUS68900.1 - 3.9 5.5 58.9 0.048 11.8 41.3 2.1 2 0 0 2 2 2 0 DNA polymerase phi RVT_1 PF00078.27 RUS68901.1 - 8.7e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BBE PF08031.12 RUS68902.1 - 1.5e-06 28.2 0.1 4.1e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 RUS68903.1 - 8.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ATP-grasp_2 PF08442.10 RUS68905.1 - 2.4e-78 262.3 0.2 2.4e-78 262.3 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 RUS68905.1 - 2.4e-26 92.4 1.5 5e-26 91.3 1.5 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 RUS68905.1 - 1.2e-11 44.5 0.9 1.4e-10 41.0 0.9 2.3 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 RUS68905.1 - 1e-05 25.4 0.1 2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 RUS68905.1 - 0.027 14.0 0.2 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 ATP-grasp domain Ligase_CoA PF00549.19 RUS68906.1 - 1e-19 70.8 0.5 1.5e-19 70.3 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 RUS68906.1 - 6.5e-10 39.6 1.0 6.5e-10 39.6 1.0 2.4 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 RUS68906.1 - 9.1e-09 35.2 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 RUS68906.1 - 0.00055 20.4 0.1 0.0015 19.0 0.1 1.8 2 0 0 2 2 2 1 CoA binding domain ABC_tran PF00005.27 RUS68907.1 - 4.2e-53 179.6 0.4 6.4e-26 91.5 0.1 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS68907.1 - 5.5e-16 59.2 16.0 7.2e-05 22.7 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS68907.1 - 4.2e-15 55.8 3.7 3.1e-07 30.0 1.7 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RUS68907.1 - 3.3e-10 39.5 0.1 0.00026 20.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS68907.1 - 1.5e-08 34.8 1.6 0.0017 18.3 0.2 2.6 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS68907.1 - 5.1e-08 33.0 0.1 0.0012 18.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 RUS68907.1 - 7.3e-08 32.7 0.1 0.00036 20.6 0.0 2.8 2 1 0 2 2 2 2 Dynamin family ABC_tran_Xtn PF12848.7 RUS68907.1 - 7.8e-08 32.2 0.4 2e-07 31.0 0.4 1.6 2 0 0 2 2 1 1 ABC transporter AAA_15 PF13175.6 RUS68907.1 - 1.1e-06 28.7 19.8 0.0013 18.6 0.2 4.4 2 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 RUS68907.1 - 1.8e-06 28.3 3.0 0.047 14.0 0.2 3.7 2 2 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 RUS68907.1 - 2.7e-06 27.2 0.0 0.072 12.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 RUS68907.1 - 3.2e-06 26.5 0.1 0.02 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 RUS68907.1 - 3.4e-06 27.7 8.0 0.0012 19.4 0.4 3.3 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 RUS68907.1 - 8.3e-06 26.4 1.0 0.032 14.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 RUS68907.1 - 2.6e-05 24.0 0.1 0.38 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 RUS68907.1 - 3e-05 24.3 0.0 0.037 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 RUS68907.1 - 4.9e-05 23.5 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS68907.1 - 5.2e-05 23.7 0.0 0.2 12.0 0.0 2.6 2 2 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 RUS68907.1 - 9.9e-05 22.7 0.1 0.19 12.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 RUS68907.1 - 0.0002 21.4 0.1 0.2 11.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 RUS68907.1 - 0.00021 21.3 1.4 0.044 13.7 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 RUS68907.1 - 0.00021 21.5 0.0 0.0063 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RUS68907.1 - 0.00065 19.0 0.0 1.4 8.1 0.0 2.8 2 1 0 2 2 2 2 NB-ARC domain PduV-EutP PF10662.9 RUS68907.1 - 0.0011 18.7 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 RUS68907.1 - 0.0011 18.3 0.0 0.77 9.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 RUS68907.1 - 0.0017 18.1 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 RUS68907.1 - 0.0017 17.9 0.1 2.1 7.8 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region G-alpha PF00503.20 RUS68907.1 - 0.0019 17.5 0.6 1.2 8.2 0.1 2.9 1 1 1 2 2 2 1 G-protein alpha subunit AAA_14 PF13173.6 RUS68907.1 - 0.003 17.6 0.2 0.21 11.6 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 RUS68907.1 - 0.0062 17.0 0.0 3.1 8.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 RUS68907.1 - 0.0073 15.7 2.7 0.36 10.1 0.1 2.6 3 0 0 3 3 2 1 AIG1 family FeoB_N PF02421.18 RUS68907.1 - 0.0078 15.8 1.0 0.098 12.2 0.2 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B dNK PF01712.19 RUS68907.1 - 0.0079 16.1 0.1 5.9 6.7 0.0 2.8 3 0 0 3 3 2 0 Deoxynucleoside kinase Arf PF00025.21 RUS68907.1 - 0.0082 15.6 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family KAP_NTPase PF07693.14 RUS68907.1 - 0.012 14.8 0.0 2.7 7.1 0.0 2.7 2 2 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 RUS68907.1 - 0.013 14.8 0.1 0.56 9.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 RUS68907.1 - 0.015 14.9 0.1 6.5 6.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain MukB PF04310.12 RUS68907.1 - 0.02 14.7 0.1 0.95 9.2 0.0 2.7 2 1 1 3 3 3 0 MukB N-terminal Ras PF00071.22 RUS68907.1 - 0.02 14.5 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Ras family Gtr1_RagA PF04670.12 RUS68907.1 - 0.02 14.2 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_30 PF13604.6 RUS68907.1 - 0.024 14.3 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RUS68907.1 - 0.025 13.6 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 RUS68907.1 - 0.038 13.7 0.0 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 RUS68907.1 - 0.039 13.1 0.2 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.17 RUS68907.1 - 0.039 14.0 3.6 2.4 8.2 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain cobW PF02492.19 RUS68907.1 - 0.046 13.3 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RUS68907.1 - 0.047 13.7 0.1 8.9 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 RUS68907.1 - 0.07 13.0 0.0 5.8 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_ATPase PF09818.9 RUS68907.1 - 0.071 11.9 0.5 6.1 5.5 0.1 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Septin PF00735.18 RUS68907.1 - 0.074 12.3 1.7 0.33 10.2 0.0 2.4 3 0 0 3 3 3 0 Septin AAA_25 PF13481.6 RUS68907.1 - 0.075 12.6 0.0 9.8 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 RUS68907.1 - 0.079 12.0 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DLIC PF05783.11 RUS68907.1 - 0.083 11.7 2.5 0.11 11.3 0.1 2.2 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) Viral_helicase1 PF01443.18 RUS68907.1 - 0.091 12.5 0.1 0.97 9.1 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 RUS68907.1 - 0.094 12.7 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 RUS68907.1 - 0.17 11.8 1.9 25 4.8 0.0 3.5 3 1 0 3 3 3 0 NTPase Band_7 PF01145.25 RUS68908.1 - 7e-10 39.2 0.1 7e-10 39.2 0.1 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 RUS68908.1 - 1e-07 31.9 0.4 2e-07 31.0 0.4 1.5 1 0 0 1 1 1 1 C-terminal region of band_7 MIase PF02426.16 RUS68908.1 - 0.57 10.4 2.5 0.64 10.2 0.3 2.1 1 1 1 2 2 2 0 Muconolactone delta-isomerase SNARE_assoc PF09335.11 RUS68909.1 - 2.4e-19 70.0 7.8 2.4e-19 70.0 7.8 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0016 PF01169.19 RUS68909.1 - 0.034 14.5 8.0 0.096 13.0 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 AMNp_N PF10423.9 RUS68909.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Transgly_assoc PF04226.13 RUS68909.1 - 2.6 8.4 10.6 1.2 9.5 5.7 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein IF3_C PF00707.22 RUS68910.1 - 6.8e-38 128.5 1.5 1.5e-37 127.4 1.5 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 RUS68910.1 - 2.1e-08 34.3 0.0 4.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain HLH PF00010.26 RUS68911.1 - 5.8e-17 61.4 0.1 1.1e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 RUS68911.1 - 0.026 14.2 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain DUF4898 PF16239.5 RUS68913.1 - 9.2 6.3 11.2 11 6.1 3.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4898) V-ATPase_G PF03179.15 RUS68915.1 - 0.18 12.4 1.3 0.34 11.5 1.3 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit LprI PF07007.12 RUS68915.1 - 0.32 11.7 2.7 1.1 10.0 1.7 2.1 1 1 1 2 2 2 0 Lysozyme inhibitor LprI DEAD PF00270.29 RUS68916.1 - 1.2e-43 149.0 0.0 2.7e-43 147.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RUS68916.1 - 6.9e-05 22.9 0.0 0.00024 21.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS68916.1 - 0.17 12.3 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Innexin PF00876.18 RUS68917.1 - 1.3e-106 356.8 13.3 1.5e-106 356.6 13.3 1.0 1 0 0 1 1 1 1 Innexin P22_Cro PF14549.6 RUS68918.1 - 0.00018 21.3 0.8 31 4.5 0.0 4.1 4 0 0 4 4 4 0 DNA-binding transcriptional regulator Cro TRAF_BIRC3_bd PF16673.5 RUS68918.1 - 0.00021 21.0 0.9 42 4.0 0.0 4.1 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain TAF PF02969.17 RUS68918.1 - 0.0016 18.6 0.0 36 4.6 0.0 3.7 4 0 0 4 4 4 0 TATA box binding protein associated factor (TAF) SecE PF00584.20 RUS68918.1 - 0.0065 16.4 5.0 51 3.9 0.1 4.1 4 0 0 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex VWA_2 PF13519.6 RUS68918.1 - 0.019 15.6 0.1 1.8e+02 2.8 0.0 3.9 1 1 2 4 4 4 0 von Willebrand factor type A domain Hpt PF01627.23 RUS68918.1 - 0.032 14.5 0.0 97 3.3 0.0 3.5 3 0 0 3 3 3 0 Hpt domain YojJ PF10372.9 RUS68918.1 - 0.04 14.0 5.0 82 3.4 0.1 4.0 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus SseC PF04888.12 RUS68919.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SelP_N PF04592.14 RUS68919.1 - 0.22 10.9 12.5 0.3 10.4 12.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.14 RUS68920.1 - 0.29 9.4 3.6 0.38 9.0 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein EPL1 PF10513.9 RUS68920.1 - 3.3 8.1 8.8 0.6 10.5 1.7 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4175 PF13779.6 RUS68920.1 - 3.8 5.3 13.7 5.6 4.8 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Trypsin PF00089.26 RUS68922.1 - 1.7e-31 109.8 0.0 1.9e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RUS68922.1 - 5.1e-05 23.6 0.3 0.00044 20.6 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 RUS68923.1 - 6.7e-28 96.6 63.6 6.8e-11 42.2 11.0 5.6 5 1 0 5 5 5 3 Low-density lipoprotein receptor domain class A Fz PF01392.22 RUS68923.1 - 1.5e-07 32.1 41.6 1e-05 26.1 41.6 3.0 1 1 0 1 1 1 1 Fz domain CUB PF00431.20 RUS68924.1 - 4.1e-29 101.1 0.1 4.9e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 CUB domain RecA PF00154.21 RUS68926.1 - 6.8e-142 471.6 4.4 8.1e-142 471.3 4.4 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 RUS68926.1 - 3.2e-10 39.7 0.8 3e-09 36.5 0.8 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 RUS68926.1 - 1.5e-07 31.0 2.9 7.9e-06 25.4 0.2 2.9 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 RUS68926.1 - 0.0014 18.3 0.9 0.042 13.4 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RUS68926.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RUS68926.1 - 0.0031 17.4 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea OmpH PF03938.14 RUS68927.1 - 3.3e-15 56.6 21.4 1.1e-14 54.9 21.4 1.7 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) FapA PF03961.13 RUS68927.1 - 0.00071 18.3 1.6 0.00072 18.3 1.6 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Sigma70_ner PF04546.13 RUS68927.1 - 0.0018 18.2 16.2 0.0027 17.6 16.2 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Gon7 PF08738.10 RUS68927.1 - 0.017 15.2 3.9 0.017 15.2 3.9 2.0 1 1 1 2 2 2 0 Gon7 family GldM_N PF12081.8 RUS68927.1 - 0.037 14.1 13.5 0.051 13.7 13.5 1.1 1 0 0 1 1 1 0 GldM N-terminal domain KinB_sensor PF16767.5 RUS68927.1 - 0.04 14.4 5.0 5.6 7.4 2.3 2.7 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB CENP-O PF09496.10 RUS68927.1 - 0.091 12.7 4.7 0.11 12.4 4.7 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Lipoprotein_6 PF01441.19 RUS68927.1 - 0.15 12.0 14.6 0.14 12.1 13.3 1.5 1 1 0 1 1 1 0 Lipoprotein CDC45 PF02724.14 RUS68927.1 - 0.3 9.3 13.3 0.37 9.0 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 RUS68927.1 - 0.31 11.3 12.0 1.5 9.1 7.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Uds1 PF15456.6 RUS68927.1 - 0.77 9.9 10.9 1.1 9.4 10.9 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Syntaxin_2 PF14523.6 RUS68927.1 - 0.8 10.1 9.5 1.2 9.6 8.9 1.6 1 1 1 2 2 2 0 Syntaxin-like protein CDPS PF16715.5 RUS68927.1 - 1.1 8.9 5.6 1.4 8.5 5.6 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase Prominin PF05478.11 RUS68927.1 - 1.1 7.1 5.0 1.6 6.5 5.0 1.3 1 0 0 1 1 1 0 Prominin SOGA PF11365.8 RUS68927.1 - 1.2 10.4 6.8 16 6.7 6.3 2.3 1 1 1 2 2 2 0 Protein SOGA PRKG1_interact PF15898.5 RUS68927.1 - 3.2 8.7 12.7 3.7 8.5 10.3 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3391 PF11871.8 RUS68927.1 - 3.2 8.3 10.8 5.9 7.4 10.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) ALMT PF11744.8 RUS68927.1 - 4.7 5.9 7.4 6.6 5.4 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter YabA PF06156.13 RUS68927.1 - 6.2 7.5 6.9 9.9 6.9 1.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DOG1 PF14144.6 RUS68927.1 - 6.2 7.1 7.0 14 5.9 1.7 2.5 2 1 0 2 2 2 0 Seed dormancy control GREB1 PF15782.5 RUS68927.1 - 6.4 3.8 9.9 7.3 3.6 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Vfa1 PF08432.10 RUS68927.1 - 9.1 6.6 20.5 16 5.8 20.5 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Guanylate_cyc PF00211.20 RUS68928.1 - 2e-63 213.3 0.0 2.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 RUS68933.1 - 8.5e-41 139.9 0.0 1.3e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS68933.1 - 2.1e-13 50.2 0.6 4.6e-13 49.0 0.6 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS68933.1 - 6.2e-06 25.9 0.5 1.7e-05 24.4 0.4 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 RUS68933.1 - 2e-05 24.8 0.0 0.0003 21.0 0.0 2.4 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS68933.1 - 0.00095 19.8 1.5 0.0026 18.4 1.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FF PF01846.19 RUS68933.1 - 0.65 10.2 3.5 0.39 10.9 0.5 2.2 2 0 0 2 2 2 0 FF domain Pkinase PF00069.25 RUS68934.1 - 4.3e-29 101.7 0.0 5.3e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS68934.1 - 3.5e-20 72.4 0.0 4.1e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS68934.1 - 0.00056 18.8 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS68934.1 - 0.0013 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS68934.1 - 0.0061 16.2 0.2 0.94 9.1 0.1 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RUS68934.1 - 0.012 15.0 0.1 0.77 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 RUS68935.1 - 2.5e-18 66.4 0.1 5.8e-06 25.9 0.0 3.8 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RUS68935.1 - 1.1e-11 44.5 0.1 5.4e-05 22.6 0.1 3.6 3 1 1 4 4 4 3 Protein tyrosine kinase ABC_tran PF00005.27 RUS68936.1 - 2.2e-15 57.4 0.0 3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RUS68936.1 - 1.2e-05 25.3 0.1 1.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 RUS68936.1 - 0.00017 22.2 0.3 0.00023 21.7 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RUS68936.1 - 0.00056 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 RUS68936.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DLIC PF05783.11 RUS68936.1 - 0.014 14.2 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_15 PF13175.6 RUS68936.1 - 0.019 14.7 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 RUS68936.1 - 0.025 14.7 0.2 0.042 13.9 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 RUS68936.1 - 0.036 13.8 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 RUS68936.1 - 0.039 13.6 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 RUS68936.1 - 0.058 13.4 0.1 0.095 12.7 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 RUS68936.1 - 0.095 12.3 0.4 0.19 11.3 0.3 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 RUS68936.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RUS68936.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 RUS68936.1 - 0.12 12.2 0.9 0.22 11.3 0.4 1.5 1 1 1 2 2 2 0 MukB N-terminal Roc PF08477.13 RUS68936.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS68936.1 - 0.17 12.3 0.1 0.72 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 RUS68936.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 RUS68936.1 - 0.25 10.0 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain RT_RNaseH_2 PF17919.1 RUS68938.1 - 8.8e-12 44.9 0.0 2.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS68938.1 - 0.044 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase WAP PF00095.21 RUS68939.1 - 1.3e-07 31.9 13.7 1.3e-07 31.9 13.7 4.1 4 0 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' EGF PF00008.27 RUS68939.1 - 3.1e-06 27.4 33.6 1.7e-05 25.0 7.4 3.7 3 0 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 RUS68939.1 - 4.7e-05 23.7 29.7 0.00069 19.9 10.7 3.7 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 RUS68939.1 - 0.011 16.4 5.0 0.011 16.4 5.0 4.6 4 2 1 5 5 5 0 Human growth factor-like EGF Synaptobrevin PF00957.21 RUS68940.1 - 3.1e-34 116.6 1.4 4.7e-34 116.0 1.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RUS68940.1 - 1.5e-26 92.3 0.4 2.2e-26 91.7 0.4 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 RUS68940.1 - 0.02 14.8 0.4 0.029 14.3 0.4 1.2 1 0 0 1 1 1 0 Rifin ODV-E18 PF10717.9 RUS68940.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 MCU PF04678.13 RUS68940.1 - 0.27 11.3 2.1 0.24 11.5 0.5 1.6 1 1 0 2 2 2 0 Mitochondrial calcium uniporter Afaf PF15339.6 RUS68940.1 - 1.9 8.2 5.0 5.8 6.6 4.3 2.0 2 1 0 2 2 2 0 Acrosome formation-associated factor K_channel_TID PF07941.11 RUS68942.1 - 0.00012 22.4 7.5 0.00025 21.4 7.5 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Tad PF13400.6 RUS68942.1 - 1.1 9.7 11.7 6 7.3 11.3 2.1 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Guanylate_cyc PF00211.20 RUS68943.1 - 1.4e-20 73.7 0.0 1.5e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MULE PF10551.9 RUS68945.1 - 2.5e-06 27.8 0.2 7.5e-06 26.3 0.2 1.9 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 RUS68945.1 - 0.0065 16.1 1.6 0.0065 16.1 1.6 2.5 3 0 0 3 3 3 1 SWIM zinc finger CUB PF00431.20 RUS68946.1 - 7.7e-45 151.7 0.0 5.6e-26 91.0 0.0 2.0 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 RUS68946.1 - 0.0047 16.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 CUB-like domain Coprogen_oxidas PF01218.18 RUS68947.1 - 1.5e-124 414.5 0.1 1.7e-124 414.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DnaB_C PF03796.15 RUS68948.1 - 1.3e-25 90.2 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Ribosomal_L9_N PF01281.19 RUS68948.1 - 7.4e-14 51.0 0.1 1.7e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 RUS68948.1 - 2e-13 50.6 0.7 5.7e-12 45.9 0.1 2.7 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain PseudoU_synth_2 PF00849.22 RUS68948.1 - 0.00021 21.4 0.0 0.0011 19.0 0.0 2.2 2 1 0 2 2 2 1 RNA pseudouridylate synthase CBS PF00571.28 RUS68948.1 - 0.0027 18.1 0.1 0.0062 17.0 0.1 1.6 1 0 0 1 1 1 1 CBS domain Lipase_GDSL_2 PF13472.6 RUS68948.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pribosyltran_N PF13793.6 RUS68949.1 - 3.7e-30 104.2 0.1 7.5e-29 100.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 RUS68949.1 - 1.1e-21 77.1 0.5 7.1e-21 74.4 0.3 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 RUS68949.1 - 1.4e-17 64.4 3.2 1.5e-16 61.0 0.4 2.4 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 RUS68949.1 - 0.00039 19.9 0.1 0.00056 19.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CN_hydrolase PF00795.22 RUS68950.1 - 2.8e-34 118.6 0.0 3.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1030 PF06270.11 RUS68950.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Spc7 PF08317.11 RUS68951.1 - 6.9e-05 21.9 10.9 6.9e-05 21.9 10.9 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Cdh1_DBD_1 PF18196.1 RUS68951.1 - 0.0035 17.7 7.2 0.0035 17.7 7.2 1.9 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 CSRNP_N PF16019.5 RUS68951.1 - 0.025 14.5 2.4 0.038 13.9 2.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FapA PF03961.13 RUS68951.1 - 0.085 11.4 5.4 0.11 11.1 5.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 RUS68951.1 - 0.23 10.3 4.6 0.26 10.1 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Dfp1_Him1_M PF08630.10 RUS68951.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.4 2 0 0 2 2 2 0 Dfp1/Him1, central region Laminin_II PF06009.12 RUS68951.1 - 0.65 10.0 15.6 5 7.1 15.6 2.2 1 1 1 2 2 2 0 Laminin Domain II SOBP PF15279.6 RUS68951.1 - 0.76 10.3 14.6 0.99 10.0 14.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CorA PF01544.18 RUS68951.1 - 0.79 9.0 7.0 0.22 10.8 4.1 1.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF572 PF04502.13 RUS68951.1 - 1.6 8.3 12.8 2 8.0 12.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sec8_exocyst PF04048.14 RUS68951.1 - 1.7 8.5 15.4 4.8 7.1 9.5 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain ArlS_N PF18719.1 RUS68951.1 - 2.2 8.5 11.6 8.7 6.6 11.6 2.0 1 1 0 1 1 1 0 ArlS sensor domain KxDL PF10241.9 RUS68951.1 - 4.4 7.7 18.7 8.9 6.7 11.0 3.0 3 1 0 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 RUS68951.1 - 9.1 6.3 12.6 1.5 8.9 7.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 RUS68952.1 - 1.1e-10 41.0 2.1 1.3e-10 40.8 2.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS68952.1 - 0.00013 20.9 4.2 0.00019 20.4 4.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4203 PF13886.6 RUS68952.1 - 0.0021 17.8 8.3 0.0063 16.2 7.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) MFS_2 PF13347.6 RUS68952.1 - 0.027 13.0 6.5 0.044 12.3 6.1 1.6 1 1 0 1 1 1 0 MFS/sugar transport protein DUF4179 PF13786.6 RUS68952.1 - 0.18 12.3 0.4 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF5326 PF17260.2 RUS68952.1 - 7.9 6.7 6.9 0.66 10.1 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) AOX PF01786.17 RUS68953.1 - 5.3e-90 300.7 0.3 7.1e-90 300.3 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase FA_desaturase PF00487.24 RUS68954.1 - 2.1e-17 63.8 15.2 3.4e-17 63.1 15.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase TssN PF17555.2 RUS68954.1 - 0.55 9.6 10.8 2.4 7.5 1.8 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN Phage_holin_3_6 PF07332.11 RUS68954.1 - 1.5 8.9 8.5 0.45 10.6 0.6 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Caveolin PF01146.17 RUS68954.1 - 5.7 6.9 7.8 0.46 10.4 0.3 2.6 3 0 0 3 3 3 0 Caveolin TctA PF01970.16 RUS68954.1 - 9.5 4.8 11.3 0.69 8.6 3.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family RNA_pol_Rpb2_6 PF00562.28 RUS68955.1 - 5.2e-79 266.1 1.1 5.9e-79 265.9 1.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RUS68955.1 - 4.6e-15 55.8 0.1 8.2e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Ribosomal_L1 PF00687.21 RUS68956.1 - 8.4e-35 120.4 0.0 1.6e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 RUS68956.1 - 6.2e-31 106.0 2.7 3.1e-30 103.8 0.5 2.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L12 PF00542.19 RUS68956.1 - 5.8e-28 97.0 4.8 5.8e-28 97.0 4.8 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L11 PF00298.19 RUS68956.1 - 2.6e-19 69.5 3.0 5.2e-19 68.5 0.1 2.7 3 0 0 3 3 3 1 Ribosomal protein L11, RNA binding domain Ribosomal_L12_N PF16320.5 RUS68956.1 - 3.5e-12 45.8 5.0 3.5e-12 45.8 5.0 2.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF2125 PF09898.9 RUS68956.1 - 0.067 12.9 4.3 0.48 10.0 3.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) Surface_antigen PF11054.8 RUS68956.1 - 0.11 12.1 1.0 0.18 11.5 1.0 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen GTP_EFTU PF00009.27 RUS68957.1 - 6.2e-46 156.4 0.0 8.1e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RUS68957.1 - 1.7e-34 118.5 0.6 2.6e-34 117.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RUS68957.1 - 4.2e-17 62.3 6.6 4.2e-17 62.3 6.6 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 RUS68957.1 - 0.049 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 RUS68957.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AA_kinase PF00696.28 RUS68958.1 - 1.8e-46 158.7 4.7 4.6e-46 157.4 4.7 1.7 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 RUS68958.1 - 3.2e-23 82.0 5.0 2.1e-17 62.8 0.6 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 RUS68958.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Citrate_synt PF00285.21 RUS68959.1 - 6.1e-95 318.3 0.5 7.1e-95 318.1 0.5 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FAD_binding_2 PF00890.24 RUS68960.1 - 4.3e-121 404.9 1.6 5.6e-121 404.5 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RUS68960.1 - 8.2e-38 129.3 0.4 1.5e-37 128.5 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 RUS68960.1 - 2e-07 30.5 0.2 0.00016 21.0 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS68960.1 - 3.6e-05 23.1 0.5 0.0041 16.4 0.2 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 RUS68960.1 - 0.00011 22.0 1.0 0.00067 19.3 0.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 RUS68960.1 - 0.00013 21.2 2.4 0.00049 19.3 1.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RUS68960.1 - 0.0051 16.1 0.2 0.0087 15.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RUS68960.1 - 0.0055 15.5 1.5 0.01 14.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 RUS68960.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb4 PF03874.16 RUS68960.1 - 0.069 13.5 0.8 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 NAD_binding_8 PF13450.6 RUS68960.1 - 0.073 13.3 0.8 0.21 11.8 0.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RUS68960.1 - 0.14 11.5 4.7 2.4 7.4 1.1 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 RUS68960.1 - 0.15 12.5 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-oxoacid_dh PF00198.23 RUS68961.1 - 1.5e-81 273.3 0.0 2.1e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RUS68961.1 - 4e-18 65.0 1.7 5e-18 64.7 0.6 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 RUS68961.1 - 3.9e-06 27.1 0.1 9.2e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RUS68961.1 - 1e-05 25.2 0.1 0.00022 21.0 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 RUS68961.1 - 0.0025 18.5 3.6 0.011 16.4 0.1 2.6 2 1 1 3 3 3 1 HlyD family secretion protein Ecm29 PF13001.7 RUS68962.1 - 0.0022 16.8 0.1 0.45 9.1 0.0 2.8 2 1 1 3 3 3 2 Proteasome stabiliser Glyco_tran_WecB PF03808.13 RUS68962.1 - 0.026 14.5 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Vac14_Fab1_bd PF12755.7 RUS68962.1 - 0.16 12.6 1.3 13 6.4 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Pertussis_S1 PF02917.14 RUS68963.1 - 0.029 14.1 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 SAM_2 PF07647.17 RUS68965.1 - 2.3e-11 43.6 0.3 3.2e-11 43.2 0.3 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS68965.1 - 8.8e-10 38.9 0.5 1.4e-09 38.3 0.5 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAPS_reduct PF01507.19 RUS68965.1 - 0.061 13.4 0.1 0.15 12.1 0.0 1.6 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family LRR_9 PF14580.6 RUS68966.1 - 2.7e-18 66.1 0.2 3.3e-18 65.8 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RUS68966.1 - 1.5e-15 57.1 16.4 3.4e-09 36.8 2.2 3.6 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS68966.1 - 4.5e-09 35.9 9.6 0.00051 19.8 1.1 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 RUS68966.1 - 4.9e-05 23.1 13.9 0.0082 16.1 0.6 4.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 RUS68966.1 - 0.0052 17.2 11.1 3.2 8.7 0.2 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat HEAT_2 PF13646.6 RUS68967.1 - 5.8e-10 39.4 4.1 5.9e-08 33.0 0.2 2.5 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.23 RUS68967.1 - 7.2e-09 35.4 0.1 0.00094 19.1 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RUS68967.1 - 8.9e-09 34.9 2.5 0.005 17.0 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 RUS68967.1 - 3.3e-06 27.5 3.1 0.22 12.1 0.1 3.7 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 RUS68967.1 - 7.2e-06 26.1 2.5 3.3e-05 24.0 2.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RUS68967.1 - 0.00066 18.4 1.4 0.0072 14.9 1.5 2.0 1 1 1 2 2 2 1 Adaptin N terminal region RasGEF_N_2 PF14663.6 RUS68967.1 - 0.004 17.5 1.1 6.8 7.1 0.1 3.0 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 RUS68967.1 - 0.0058 16.1 0.0 0.023 14.1 0.0 1.9 1 1 2 3 3 3 1 Armadillo-like Vac14_Fab1_bd PF12755.7 RUS68967.1 - 0.0081 16.7 0.2 0.042 14.4 0.0 2.1 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 RUS68967.1 - 0.035 14.0 0.3 0.22 11.4 0.1 2.1 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus Fanconi_C PF02106.15 RUS68967.1 - 0.065 11.9 0.1 0.075 11.7 0.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein MMS19_N PF14500.6 RUS68967.1 - 0.079 12.5 0.7 0.75 9.3 0.1 2.3 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3636 PF12331.8 RUS68967.1 - 0.084 12.7 0.1 3 7.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3636) Tti2 PF10521.9 RUS68967.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Tti2 family cNMP_binding PF00027.29 RUS68968.1 - 2.2e-13 50.1 0.3 1.3e-09 38.0 0.1 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Baculo_PEP_C PF04513.12 RUS68969.1 - 0.0073 16.4 2.3 0.22 11.6 1.7 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus FIVAR PF07554.13 RUS68969.1 - 0.015 16.0 4.3 0.92 10.3 0.1 3.4 2 1 1 3 3 3 0 FIVAR domain Vinculin PF01044.19 RUS68969.1 - 0.021 13.1 3.0 0.18 10.0 0.3 2.7 1 1 1 3 3 3 0 Vinculin family CheZ PF04344.13 RUS68969.1 - 0.059 13.3 0.6 0.51 10.2 0.4 2.2 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Synaptobrevin PF00957.21 RUS68969.1 - 0.086 12.6 0.4 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 Synaptobrevin Tape_meas_lam_C PF09718.10 RUS68969.1 - 0.2 11.8 1.3 4.8 7.4 0.3 3.2 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin_2 PF09361.10 RUS68969.1 - 0.36 11.1 2.6 3.8 7.8 0.8 2.8 1 1 1 2 2 2 0 Phasin protein Ribosomal_L7Ae PF01248.26 RUS68970.1 - 3e-06 26.9 0.1 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aldedh PF00171.22 RUS68971.1 - 1.9e-107 359.7 0.0 1.4e-56 192.0 0.1 2.4 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Peptidase_M2 PF01401.18 RUS68972.1 - 3.1e-194 646.8 3.1 6.8e-194 645.7 3.1 1.5 1 1 0 1 1 1 1 Angiotensin-converting enzyme Integrase_H2C2 PF17921.1 RUS68973.1 - 2.2e-14 53.3 0.3 3.7e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS68973.1 - 2.4e-09 37.4 0.0 5.4e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS68973.1 - 1.4e-08 34.8 0.1 2.3e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Qn_am_d_aIV PF09100.10 RUS68973.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV zf-CCHC PF00098.23 RUS68974.1 - 5.8e-08 32.5 13.3 0.00037 20.5 1.6 2.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 RUS68974.1 - 0.00084 19.1 0.7 0.00084 19.1 0.7 2.3 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68974.1 - 0.0043 16.8 7.2 0.18 11.5 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle RHH_1 PF01402.21 RUS68974.1 - 0.21 11.6 2.5 0.58 10.2 0.3 2.6 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family zf-CCHC_5 PF14787.6 RUS68974.1 - 2.4 8.0 19.5 0.27 11.0 3.0 3.4 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger Neur_chan_LBD PF02931.23 RUS68975.1 - 1.5e-33 116.1 0.2 2e-33 115.7 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS68975.1 - 9.2e-18 65.2 2.1 3.6e-17 63.2 2.1 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.29 RUS68976.1 - 5.8e-17 62.0 0.0 1.4e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase C2-set_2 PF08205.12 RUS68977.1 - 6.5e-08 32.5 3.8 0.03 14.4 0.3 3.4 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 RUS68977.1 - 5.4e-07 30.1 7.3 0.17 12.5 0.6 3.6 3 0 0 3 3 3 3 Immunoglobulin domain RNA_pol_Rpb2_7 PF04560.20 RUS68977.1 - 0.17 12.3 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 C2-set_2 PF08205.12 RUS68978.1 - 4.6e-07 29.8 13.7 0.0065 16.5 0.5 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain I-set PF07679.16 RUS68978.1 - 0.00085 19.3 2.7 0.5 10.5 0.0 4.0 3 2 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS68978.1 - 0.0039 17.7 23.6 0.49 11.0 1.1 5.2 5 0 0 5 5 5 3 Immunoglobulin domain TMEM154 PF15102.6 RUS68978.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family GLEYA PF10528.9 RUS68978.1 - 0.086 13.3 1.8 14 6.2 0.0 3.2 3 1 0 3 3 3 0 GLEYA domain LapA_dom PF06305.11 RUS68978.1 - 0.26 11.1 0.7 0.48 10.3 0.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-CCHC PF00098.23 RUS68979.1 - 0.00029 20.8 10.1 0.11 12.7 3.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-C2HC5 PF06221.13 RUS68979.1 - 0.62 10.1 3.9 3.3 7.8 3.9 2.0 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PNMA PF14893.6 RUS68980.1 - 4.6e-06 26.3 0.1 1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 PNMA Spuma_A9PTase PF03539.14 RUS68980.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) Gag_p24 PF00607.20 RUS68980.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) RILP PF11461.8 RUS68980.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein zf-CCHC PF00098.23 RUS68981.1 - 0.071 13.2 8.1 0.26 11.4 0.6 3.0 2 1 0 2 2 2 0 Zinc knuckle E_Pc_C PF06752.12 RUS68981.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus zf-CCHC_5 PF14787.6 RUS68981.1 - 4.4 7.1 10.6 0.53 10.0 1.9 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 RUS68982.1 - 1.2e-05 25.2 1.5 2.4e-05 24.2 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 RUS68982.1 - 0.0012 18.6 0.4 0.0027 17.5 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 RUS68982.1 - 0.0013 18.4 0.2 0.0036 17.0 0.1 1.8 2 0 0 2 2 2 1 Zinc knuckle SCAN PF02023.17 RUS68982.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 SCAN domain BESS PF02944.20 RUS68982.1 - 0.033 14.0 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 BESS motif LupA PF18242.1 RUS68982.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Legionella ubiquitin-specific protease A domain CD225 PF04505.12 RUS68983.1 - 0.0002 21.4 0.1 0.00034 20.7 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein p450 PF00067.22 RUS68984.1 - 6.3e-106 354.9 0.0 7.4e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pep_M12B_propep PF01562.19 RUS68986.1 - 4.5e-08 33.4 0.0 1.3e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Reprolysin family propeptide CENP-B_dimeris PF09026.10 RUS68986.1 - 0.051 14.0 1.3 0.11 12.9 1.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Lig_chan PF00060.26 RUS68988.1 - 1.4e-29 102.9 0.1 2.2e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS68988.1 - 1.4e-23 83.3 0.0 2.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS68988.1 - 7.5e-15 55.0 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 FtsH_ext PF06480.15 RUS68988.1 - 0.012 16.0 2.0 0.069 13.5 0.0 3.0 3 0 0 3 3 3 0 FtsH Extracellular DUF4079 PF13301.6 RUS68988.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF1180 PF06679.12 RUS68988.1 - 0.24 11.8 1.2 0.5 10.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ion_trans PF00520.31 RUS68988.1 - 0.24 10.6 2.8 0.42 9.8 2.8 1.3 1 0 0 1 1 1 0 Ion transport protein Ion_trans_2 PF07885.16 RUS68988.1 - 6.2 6.9 7.4 24 5.0 7.5 2.0 1 1 0 1 1 1 0 Ion channel Paramyxo_PNT PF14320.6 RUS68989.1 - 8.5e-05 21.9 0.4 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoprotein P region PNT disordered DUF3130 PF11328.8 RUS68989.1 - 0.011 16.0 0.1 7.7 6.8 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3130 DUF4477 PF14780.6 RUS68989.1 - 0.039 13.6 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) HisK_N PF09385.10 RUS68989.1 - 0.12 12.3 0.1 60 3.6 0.0 3.4 3 0 0 3 3 3 0 Histidine kinase N terminal DNA_pol_E_B PF04042.16 RUS68989.1 - 0.37 10.1 6.3 2.6 7.3 0.7 2.5 1 1 1 2 2 2 0 DNA polymerase alpha/epsilon subunit B DUF3244 PF11589.8 RUS68990.1 - 0.023 14.8 0.6 0.029 14.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) FIT1_2 PF17357.2 RUS68990.1 - 0.076 13.1 8.7 0.11 12.6 8.7 1.2 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Y_phosphatase PF00102.27 RUS68991.1 - 3.4e-74 249.4 0.9 3.4e-74 249.4 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS68991.1 - 7.8e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTP_tm PF18861.1 RUS68991.1 - 0.0031 17.6 1.0 0.0031 17.6 1.0 1.9 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Y_phosphatase3 PF13350.6 RUS68991.1 - 0.0081 16.1 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family EphA2_TM PF14575.6 RUS68991.1 - 0.027 15.3 0.0 0.099 13.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PTPlike_phytase PF14566.6 RUS68991.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate LPG_synthase_TM PF03706.13 RUS68991.1 - 0.055 13.0 0.1 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region PepSY_TM PF03929.16 RUS68991.1 - 0.061 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM region DUF4381 PF14316.6 RUS68991.1 - 0.082 13.1 0.8 0.13 12.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) BA14K PF07886.11 RUS68991.1 - 0.11 12.4 0.8 0.4 10.6 0.5 2.1 2 0 0 2 2 2 0 BA14K-like protein TH1 PF04858.13 RUS68992.1 - 1.6e-242 806.3 0.1 1.9e-242 806.1 0.1 1.0 1 0 0 1 1 1 1 TH1 protein Adaptin_N PF01602.20 RUS68992.1 - 0.0055 15.3 1.4 0.24 9.9 0.3 2.9 3 0 0 3 3 3 1 Adaptin N terminal region SfsA PF03749.13 RUS68992.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain MIIP PF15734.5 RUS68994.1 - 3.2e-52 178.1 7.0 3.2e-52 178.1 7.0 1.7 2 0 0 2 2 2 1 Migration and invasion-inhibitory Big_9 PF17963.1 RUS68995.1 - 0.00061 20.5 33.4 0.0056 17.4 9.6 4.7 4 2 0 4 4 4 2 Bacterial Ig domain Cadherin_4 PF17803.1 RUS68995.1 - 0.00064 20.3 2.6 0.00064 20.3 2.6 4.0 4 0 0 4 4 4 1 Bacterial cadherin-like domain Cadherin_5 PF17892.1 RUS68995.1 - 0.0027 17.6 11.2 0.21 11.6 1.8 3.8 3 0 0 3 3 3 2 Cadherin-like domain Amnionless PF14828.6 RUS68995.1 - 0.0033 16.3 0.0 0.0094 14.8 0.0 1.7 2 0 0 2 2 2 1 Amnionless DUF1093 PF06486.11 RUS68995.1 - 0.0072 17.0 0.1 0.12 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1093) EGF PF00008.27 RUS68995.1 - 0.017 15.4 19.2 0.34 11.2 1.1 3.6 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 RUS68995.1 - 0.034 14.8 14.9 0.21 12.3 2.0 3.4 2 1 0 2 2 2 0 Human growth factor-like EGF cEGF PF12662.7 RUS68995.1 - 0.51 10.3 15.6 0.17 11.8 6.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Proteasome_A_N PF10584.9 RUS68998.1 - 0.002 17.8 6.2 29 4.5 0.1 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature FISNA PF14484.6 RUS68998.1 - 0.0022 18.2 18.2 3.6 7.9 0.2 5.0 1 1 4 5 5 5 4 Fish-specific NACHT associated domain aGPT-Pplase3 PF18746.1 RUS68998.1 - 0.0022 17.4 3.1 0.56 9.5 0.2 2.8 1 1 2 3 3 3 3 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 DUF600 PF04634.12 RUS68998.1 - 0.0083 16.2 0.7 2.2 8.3 0.1 2.8 1 1 3 4 4 4 2 Protein of unknown function, DUF600 Flp_C PF05202.12 RUS68998.1 - 0.014 14.9 9.9 0.19 11.2 1.1 3.0 1 1 2 3 3 3 0 Recombinase Flp protein NlpE PF04170.12 RUS68998.1 - 0.1 13.6 0.0 2.9 8.9 0.0 2.4 1 1 1 2 2 2 0 NlpE N-terminal domain ANAPC2 PF08672.11 RUS68998.1 - 0.14 12.6 0.0 24 5.5 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 TetR_C_10 PF16295.5 RUS68998.1 - 0.37 11.1 8.1 3.2 8.0 0.8 3.1 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DNA_primase_S PF01896.19 RUS68998.1 - 1.8 8.6 5.5 1.8 8.5 2.5 1.9 1 1 1 2 2 2 0 DNA primase small subunit Cyclin_N PF00134.23 RUS69001.1 - 3.2e-43 146.5 0.5 5.4e-43 145.8 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS69001.1 - 3.9e-07 30.2 0.8 8.5e-07 29.1 0.3 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain KR PF08659.10 RUS69002.1 - 2.3e-25 89.5 0.0 3.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 RUS69002.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS69002.1 - 5e-05 23.9 0.0 0.00014 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS69002.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS69002.1 - 0.0016 19.2 0.0 0.004 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PMT2_N PF17987.1 RUS69002.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Methyltransf_8 PF05148.15 RUS69002.1 - 0.11 12.4 0.2 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase ATP_bind_1 PF03029.17 RUS69003.1 - 0.071 12.9 0.0 0.085 12.6 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TAP_C PF03943.13 RUS69005.1 - 1.6e-21 75.7 0.2 3.4e-21 74.6 0.2 1.6 1 0 0 1 1 1 1 TAP C-terminal domain Tap-RNA_bind PF09162.10 RUS69005.1 - 3.4e-20 71.7 0.0 7.4e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Tap, RNA-binding NTF2 PF02136.20 RUS69005.1 - 1.3e-07 32.2 0.1 5.2e-07 30.3 0.0 2.1 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 RUS69005.1 - 3.2e-05 23.6 1.8 8.5e-05 22.2 1.8 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 RUS69005.1 - 0.0019 17.7 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RUS69005.1 - 0.072 13.5 5.9 0.054 13.9 2.4 2.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) ATG16 PF08614.11 RUS69007.1 - 0.0018 18.5 15.5 0.0018 18.5 15.5 6.4 2 1 4 6 6 6 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 RUS69007.1 - 0.0098 15.9 8.8 0.0098 15.9 8.8 9.0 7 3 2 9 9 9 2 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 RUS69007.1 - 0.13 12.2 8.8 0.13 12.1 0.1 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Pkinase_Tyr PF07714.17 RUS69009.1 - 5.6e-36 124.1 0.0 8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS69009.1 - 3.6e-19 69.2 0.0 5.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 RUS69009.1 - 1.6e-16 60.1 16.4 2.6e-07 30.8 0.4 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS69009.1 - 3.6e-16 59.5 1.8 4.7e-09 36.7 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69009.1 - 1.8e-15 57.1 2.6 2.6e-09 37.4 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS69009.1 - 3.4e-15 55.7 4.8 0.00034 20.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RUS69009.1 - 2.4e-14 52.0 2.8 0.00034 20.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat HMA PF00403.26 RUS69010.1 - 0.00044 20.6 2.0 10 6.6 0.0 4.5 3 2 1 4 4 4 3 Heavy-metal-associated domain Augurin PF15187.6 RUS69010.1 - 3.8 7.7 5.1 1.9e+02 2.2 4.8 3.4 1 1 2 3 3 3 0 Oesophageal cancer-related gene 4 Sulfotransfer_2 PF03567.14 RUS69011.1 - 8.8e-17 61.8 0.5 3.3e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family Kazal_1 PF00050.21 RUS69012.1 - 3.8e-11 42.8 5.2 2.3e-06 27.5 0.3 2.4 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RUS69012.1 - 5e-10 39.3 4.8 6.5e-05 23.0 0.8 2.3 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain ANF_receptor PF01094.28 RUS69013.1 - 2.2e-13 50.1 0.0 2.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS69013.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein 7TM_GPCR_Srw PF10324.9 RUS69014.1 - 1.3e-08 34.6 1.7 1.4e-08 34.4 1.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS69014.1 - 3.4e-05 23.3 0.2 4.2e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3169 PF11368.8 RUS69014.1 - 0.00073 19.1 1.1 0.00086 18.9 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) V1R PF03402.14 RUS69014.1 - 0.0054 16.4 0.5 0.0061 16.2 0.5 1.2 1 0 0 1 1 1 1 Vomeronasal organ pheromone receptor family, V1R 7TM_GPCR_Sru PF10322.9 RUS69014.1 - 0.0055 16.1 1.0 0.0079 15.6 0.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru Noggin PF05806.12 RUS69014.1 - 0.047 13.6 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Noggin Orf78 PF06024.12 RUS69014.1 - 0.068 13.5 0.3 0.19 12.1 0.1 1.8 2 0 0 2 2 2 0 Orf78 (ac78) 7TM_GPCR_Srx PF10328.9 RUS69014.1 - 0.2 11.2 7.9 0.28 10.8 2.8 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Collagen PF01391.18 RUS69017.1 - 1.4e-07 31.2 31.5 1.9e-07 30.7 31.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-CCHC PF00098.23 RUS69018.1 - 2.2e-06 27.5 3.4 6e-06 26.1 3.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Phage_int_SAM_6 PF18644.1 RUS69018.1 - 0.00074 19.6 0.1 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Phage integrase SAM-like domain zf-CCHC_4 PF14392.6 RUS69018.1 - 0.098 12.4 0.7 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Phage_int_SAM_6 PF18644.1 RUS69019.1 - 0.007 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain zf-CCHC PF00098.23 RUS69020.1 - 3.8e-05 23.6 2.0 6.4e-05 22.8 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 RUS69020.1 - 0.0047 16.6 0.7 0.008 15.9 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle PIN_4 PF13638.6 RUS69020.1 - 0.014 15.7 0.5 0.024 14.9 0.5 1.5 1 0 0 1 1 1 0 PIN domain DUF848 PF05852.11 RUS69020.1 - 0.047 13.8 4.7 0.072 13.2 4.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) WHEP-TRS PF00458.20 RUS69020.1 - 0.11 12.7 0.2 12 6.2 0.0 2.3 1 1 0 2 2 2 0 WHEP-TRS domain V_ATPase_I PF01496.19 RUS69020.1 - 0.11 10.4 3.7 0.13 10.1 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 RUS69020.1 - 0.32 11.0 4.9 0.25 11.4 2.3 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CRR7 PF12095.8 RUS69020.1 - 1 9.8 4.8 0.7 10.4 2.9 1.7 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 AAA_2 PF07724.14 RUS69021.1 - 3.8e-58 196.4 0.4 4.2e-57 193.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 RUS69021.1 - 6e-36 122.5 4.4 6e-36 122.5 4.4 2.9 3 1 1 4 4 3 1 AAA lid domain ClpB_D2-small PF10431.9 RUS69021.1 - 3.7e-22 78.2 1.0 3.7e-22 78.2 1.0 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 RUS69021.1 - 5.3e-15 56.0 0.0 2.8e-07 31.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS69021.1 - 4.1e-14 52.8 0.0 2e-13 50.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS69021.1 - 8.4e-06 26.3 0.9 0.013 15.8 0.0 3.7 3 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 RUS69021.1 - 1e-05 25.8 2.0 0.0037 17.5 0.0 4.4 4 1 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 RUS69021.1 - 1.6e-05 24.7 0.0 6.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 RUS69021.1 - 0.00036 20.6 0.6 0.65 10.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 RUS69021.1 - 0.0046 16.7 0.1 3.5 7.3 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RUS69021.1 - 0.0054 16.5 0.0 0.036 13.8 0.0 2.4 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 RUS69021.1 - 0.0076 16.8 10.2 5.6 7.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain DNA_pol3_delta2 PF13177.6 RUS69021.1 - 0.015 15.1 0.0 0.27 11.0 0.0 2.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 RUS69021.1 - 0.016 14.6 0.0 0.86 8.9 0.0 2.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RUS69021.1 - 0.017 14.8 0.0 0.16 11.7 0.0 2.7 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 RUS69021.1 - 0.023 14.9 0.1 3.1 8.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 RUS69021.1 - 0.035 14.1 0.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 RUS69021.1 - 0.047 14.2 3.0 0.18 12.4 0.0 3.5 4 1 0 4 4 3 0 AAA domain AAA_7 PF12775.7 RUS69021.1 - 0.051 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 RUS69021.1 - 0.09 13.3 0.5 1.5 9.4 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Torsin PF06309.11 RUS69021.1 - 0.1 12.7 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Torsin DUF442 PF04273.13 RUS69021.1 - 0.11 12.6 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Lge1 PF11488.8 RUS69021.1 - 0.8 9.9 7.4 0.28 11.4 1.8 3.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DEC-1_N PF04625.13 RUS69021.1 - 8.4 5.3 8.5 0.13 11.3 1.4 1.5 2 0 0 2 2 1 0 DEC-1 protein, N-terminal region SDH_alpha PF03313.15 RUS69022.1 - 7.5e-91 304.4 6.0 9.1e-91 304.1 6.0 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 RUS69022.1 - 1.5e-20 74.2 0.0 3.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 RUS69022.1 - 0.017 13.7 0.2 0.025 13.2 0.2 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Glyco_hydro_3_C PF01915.22 RUS69023.1 - 2.2e-61 207.4 0.0 3.1e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RUS69023.1 - 2.6e-59 201.2 0.0 3.6e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RUS69023.1 - 9.9e-16 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain RNA_pol_Rpb1_5 PF04998.17 RUS69023.1 - 0.061 12.8 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CARDB PF07705.11 RUS69023.1 - 0.065 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 CARDB PALP PF00291.25 RUS69024.1 - 4.1e-26 92.1 0.0 5.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme p450 PF00067.22 RUS69025.1 - 1e-67 228.9 0.0 1.3e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mucin15 PF15672.5 RUS69026.1 - 0.56 9.7 14.9 9 5.7 4.9 3.0 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 MKRN1_C PF15815.5 RUS69030.1 - 0.79 10.2 6.1 26 5.3 0.2 3.9 2 1 3 5 5 5 0 E3 ubiquitin-protein ligase makorin-1, C-terminal BUD22 PF09073.10 RUS69030.1 - 1.5 8.1 16.0 1.9 7.7 16.0 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_S77 PF03420.13 RUS69031.1 - 0.048 13.3 0.4 0.076 12.7 0.4 1.2 1 0 0 1 1 1 0 Prohead core protein serine protease DUF3112 PF11309.8 RUS69031.1 - 0.11 11.9 1.9 0.29 10.6 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) ECSCR PF15820.5 RUS69031.1 - 0.18 11.6 1.1 0.52 10.2 0.3 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Spt5_N PF11942.8 RUS69032.1 - 0.055 14.5 4.5 0.13 13.2 4.5 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal G-gamma PF00631.22 RUS69035.1 - 2.6e-05 24.1 6.5 1.4 9.0 0.2 7.3 4 2 6 10 10 10 1 GGL domain DUF1447 PF07288.11 RUS69035.1 - 0.0082 16.2 20.1 0.91 9.6 0.2 6.6 3 2 3 6 6 6 1 Protein of unknown function (DUF1447) DUF2533 PF10752.9 RUS69035.1 - 0.022 15.2 9.1 1.7 9.1 1.4 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2533) DUF1153 PF06627.11 RUS69035.1 - 0.14 12.3 3.0 8.9 6.5 0.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1153) Peptidase_S3 PF00944.19 RUS69035.1 - 0.15 11.9 2.5 6.3 6.6 0.1 3.7 1 1 2 4 4 4 0 Alphavirus core protein Phasin PF05597.11 RUS69035.1 - 1.1 9.2 13.9 6.3 6.8 0.3 3.8 1 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Drf_GBD PF06371.13 RUS69035.1 - 3.2 7.3 12.5 6.9 6.2 0.6 3.3 1 1 2 3 3 3 0 Diaphanous GTPase-binding Domain DUF763 PF05559.11 RUS69035.1 - 3.3 6.8 9.4 4 6.6 4.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF763) Apolipoprotein PF01442.18 RUS69035.1 - 4.1 7.2 13.0 12 5.7 0.2 2.8 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Prefoldin PF02996.17 RUS69035.1 - 7.1 6.6 10.9 25 4.8 0.1 4.2 3 1 1 4 4 4 0 Prefoldin subunit PMC2NT PF08066.12 RUS69035.1 - 7.1 7.4 14.9 14 6.4 0.9 4.6 2 2 2 4 4 4 0 PMC2NT (NUC016) domain DUF3385 PF11865.8 RUS69037.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Nop14 PF04147.12 RUS69037.1 - 6.3 4.9 19.3 10 4.2 19.3 1.3 1 0 0 1 1 1 0 Nop14-like family Neuralized PF07177.12 RUS69038.1 - 0.045 13.7 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Neuralized Abhydrolase_3 PF07859.13 RUS69039.1 - 1e-56 192.1 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RUS69039.1 - 1.5e-09 37.2 0.6 3.1e-09 36.2 0.6 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 RUS69039.1 - 1.8e-06 27.4 0.1 1.7e-05 24.2 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RUS69039.1 - 3.3e-06 26.8 0.2 5.1e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 RUS69039.1 - 0.0012 17.8 0.0 0.57 9.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_1 PF00561.20 RUS69039.1 - 0.072 12.7 0.2 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF5491 PF17595.2 RUS69039.1 - 0.081 13.3 0.6 26 5.2 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5491) BPL_LplA_LipB PF03099.19 RUS69040.1 - 2.6e-12 46.8 0.0 2.8e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Radical_SAM PF04055.21 RUS69041.1 - 3.3e-28 99.2 0.1 5.3e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 RUS69041.1 - 1.6e-22 79.4 0.0 3.1e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 RUS69041.1 - 3e-20 72.0 0.1 5.5e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 RUS69041.1 - 2.8e-05 24.2 0.0 0.00011 22.3 0.0 2.0 1 1 0 1 1 1 1 TRAM domain B12-binding PF02310.19 RUS69041.1 - 0.1 12.6 0.0 0.64 10.1 0.0 2.2 3 0 0 3 3 3 0 B12 binding domain Fer4_12 PF13353.6 RUS69041.1 - 0.12 12.6 0.1 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Ldh_1_N PF00056.23 RUS69042.1 - 3.4e-41 140.6 0.5 5.1e-41 140.1 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RUS69042.1 - 4.2e-24 85.3 0.0 5.7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 RUS69042.1 - 0.00012 22.3 0.0 0.00059 20.0 0.0 1.8 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase C-terminal domain Glyco_hydro_4 PF02056.16 RUS69042.1 - 0.00047 19.7 0.6 0.021 14.4 0.1 2.3 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Ribosom_S12_S23 PF00164.25 RUS69042.1 - 0.11 12.2 0.1 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S12/S23 TPR_1 PF00515.28 RUS69043.1 - 9.7e-18 63.2 1.1 4.7e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS69043.1 - 2e-15 55.6 1.1 0.001 19.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat HipN PF18253.1 RUS69043.1 - 6.3e-13 48.2 0.3 1.1e-12 47.4 0.3 1.4 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_11 PF13414.6 RUS69043.1 - 7.5e-10 38.3 0.0 0.00013 21.6 0.0 2.9 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RUS69043.1 - 3.2e-08 33.1 1.5 0.0044 17.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS69043.1 - 4.2e-08 33.0 0.1 0.0056 17.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS69043.1 - 7.9e-07 29.6 0.0 0.0014 19.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS69043.1 - 9e-06 25.9 0.1 0.061 13.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS69043.1 - 7.9e-05 23.2 0.3 0.015 16.1 0.1 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS69043.1 - 0.0005 20.5 0.0 0.0053 17.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS69043.1 - 0.0064 16.6 0.0 0.8 9.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS69043.1 - 0.0084 16.7 0.2 3.1 8.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS69043.1 - 0.018 15.2 0.1 0.037 14.3 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RUS69043.1 - 0.028 14.4 0.1 2 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 RUS69043.1 - 0.032 14.3 2.0 0.42 10.7 0.2 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Cytomega_UL84 PF06284.11 RUS69043.1 - 0.89 7.9 5.2 1.2 7.6 5.2 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein OAD_gamma PF04277.13 RUS69043.1 - 5.9 7.6 5.5 1.5 9.5 2.0 1.8 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Cu2_monoox_C PF03712.15 RUS69044.1 - 4.5e-44 149.7 0.1 7.2e-44 149.1 0.1 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RUS69044.1 - 6.1e-41 139.7 0.4 1.6e-40 138.3 0.2 1.8 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 RUS69044.1 - 8.4e-29 100.3 0.1 1.9e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 RUS69044.1 - 2.2e-06 27.5 0.0 2.9e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 Cytochrome domain of cellobiose dehydrogenase ABC_membrane PF00664.23 RUS69047.1 - 1.3e-07 31.6 0.9 1.5e-07 31.3 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 RUS69048.1 - 2.7e-14 53.5 0.1 3.4e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4730 PF15873.5 RUS69048.1 - 0.12 12.7 0.2 0.24 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) UPF0093 PF03653.13 RUS69048.1 - 0.14 12.4 0.1 0.27 11.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) ABC_membrane PF00664.23 RUS69049.1 - 4.6e-37 128.2 8.1 6.1e-37 127.7 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS69049.1 - 5.2e-26 91.8 0.0 5.2e-16 59.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS69049.1 - 0.0011 18.4 0.1 0.71 9.3 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS69049.1 - 0.0012 18.9 0.1 0.0074 16.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS69049.1 - 0.031 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS69049.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RUS69049.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 RUS69049.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 RUS69049.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 RUS69049.1 - 0.15 12.5 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain SSF PF00474.17 RUS69050.1 - 2.1e-28 99.3 7.7 3.9e-28 98.5 7.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3561 PF12084.8 RUS69050.1 - 5 7.2 10.7 12 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) GDC-P PF02347.16 RUS69051.1 - 1.2e-142 475.8 0.8 1.7e-123 412.6 0.2 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 RUS69051.1 - 6.3e-17 61.6 1.6 4.3e-09 35.8 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 RUS69051.1 - 1.4e-07 31.1 0.2 0.026 13.7 0.0 3.5 4 0 0 4 4 4 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS69051.1 - 0.0065 15.8 1.7 0.054 12.8 0.0 2.6 3 0 0 3 3 3 1 Beta-eliminating lyase GCV_H PF01597.19 RUS69052.1 - 5.6e-44 149.0 0.1 6.1e-44 148.8 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 RUS69052.1 - 0.0011 18.7 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Gp_dh_C PF02800.20 RUS69053.1 - 2.1e-55 186.6 0.0 3.3e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RUS69053.1 - 1.9e-37 127.7 0.0 4.5e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 RUS69053.1 - 0.0027 17.8 0.1 0.04 14.0 0.1 2.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Acyl_transf_1 PF00698.21 RUS69054.1 - 6.7e-35 121.1 0.0 7.8e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Meis_PKNOX_N PF16493.5 RUS69054.1 - 0.018 15.4 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 PP-binding PF00550.25 RUS69055.1 - 2.6e-13 50.1 0.1 3.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 RUS69055.1 - 6.9e-10 38.7 0.1 8.2e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding_2 PF14573.6 RUS69055.1 - 3.3e-06 27.2 1.5 4.3e-06 26.9 1.5 1.4 1 1 0 1 1 1 1 Acyl-carrier adh_short_C2 PF13561.6 RUS69055.1 - 0.00011 21.8 2.1 0.00015 21.4 2.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RUS69055.1 - 0.00014 21.4 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 RUS69055.1 - 0.00073 19.5 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L50 PF10501.9 RUS69055.1 - 0.002 18.3 0.0 0.0025 17.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal subunit 39S 2-Hacid_dh_C PF02826.19 RUS69055.1 - 0.018 14.4 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MccV PF17508.2 RUS69055.1 - 0.097 13.2 0.6 0.14 12.7 0.6 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin ketoacyl-synt PF00109.26 RUS69056.1 - 1.4e-59 201.7 0.2 2.6e-59 200.9 0.2 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS69056.1 - 2.4e-33 114.7 0.1 5.4e-33 113.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 RUS69056.1 - 4.1e-06 26.5 1.7 0.0017 18.2 1.7 2.7 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 RUS69056.1 - 0.00023 20.6 0.1 0.0005 19.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 RUS69056.1 - 0.013 16.0 0.1 0.11 13.0 0.0 2.4 2 1 1 3 3 3 0 Ketoacyl-synthetase C-terminal extension I-set PF07679.16 RUS69057.1 - 0.014 15.4 0.1 0.033 14.2 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain TMEM154 PF15102.6 RUS69058.1 - 0.0023 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family C2-set_2 PF08205.12 RUS69058.1 - 0.052 13.6 1.6 0.17 12.0 0.7 2.3 2 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF4692 PF15763.5 RUS69058.1 - 0.12 12.9 0.1 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF2795 PF11387.8 RUS69058.1 - 0.41 10.9 2.0 36 4.7 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) DUF4538 PF15061.6 RUS69058.1 - 1.2 8.9 2.9 2.1 8.1 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ig_3 PF13927.6 RUS69059.1 - 6.9e-13 49.0 14.1 1.6e-05 25.4 0.1 6.0 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 RUS69059.1 - 2e-12 47.0 2.0 0.00062 19.8 0.1 5.5 5 2 1 6 6 6 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS69059.1 - 9.7e-11 41.9 12.3 1.7e-06 28.2 0.1 4.6 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 RUS69059.1 - 0.00085 19.5 14.0 0.0054 16.9 0.3 4.9 4 1 2 6 6 6 2 Immunoglobulin domain DAG1 PF05454.11 RUS69059.1 - 0.0013 18.1 0.2 0.043 13.2 0.0 2.2 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) C2-set_2 PF08205.12 RUS69059.1 - 0.016 15.2 7.2 0.23 11.5 0.5 4.4 4 1 0 4 4 4 0 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 RUS69061.1 - 3e-41 139.6 11.5 1.4e-10 41.4 0.0 5.3 5 0 0 5 5 5 5 Fibronectin type III domain Ig_3 PF13927.6 RUS69061.1 - 6.3e-18 65.1 0.1 4.8e-11 43.1 0.1 3.9 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RUS69061.1 - 7.3e-15 55.1 0.0 2.3e-09 37.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS69061.1 - 1.6e-14 53.8 0.0 3.3e-11 43.1 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain ig PF00047.25 RUS69061.1 - 7.2e-11 42.1 0.0 4.1e-07 30.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Interfer-bind PF09294.10 RUS69061.1 - 2.4e-06 27.8 1.0 0.55 10.6 0.0 4.3 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 RUS69061.1 - 2.7e-06 27.9 10.2 2.5 8.7 0.0 5.7 4 2 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 RUS69061.1 - 0.0059 16.8 0.3 4 7.7 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS69061.1 - 0.032 13.8 0.0 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain C2-set_2 PF08205.12 RUS69061.1 - 0.055 13.5 0.3 0.17 12.0 0.0 1.9 2 0 0 2 2 1 0 CD80-like C2-set immunoglobulin domain PrcB_C PF14343.6 RUS69061.1 - 0.073 13.2 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 PrcB C-terminal fn3_4 PF16794.5 RUS69061.1 - 0.2 11.6 1.6 4.8 7.2 0.0 3.5 4 0 0 4 4 4 0 Fibronectin-III type domain tRNA_int_end_N2 PF12928.7 RUS69062.1 - 3.1e-09 36.9 0.1 9.8e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 RUS69062.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Trypsin_2 PF13365.6 RUS69063.1 - 1.9e-07 32.1 0.0 3.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-C2H2 PF00096.26 RUS69064.1 - 1.4e-08 34.7 5.4 0.017 15.6 0.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69064.1 - 1.8e-07 31.4 7.4 0.017 15.9 0.2 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 RUS69064.1 - 0.0027 18.0 1.4 0.0027 18.0 1.4 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS69064.1 - 0.0098 16.3 11.1 0.081 13.4 2.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 RUS69064.1 - 0.04 13.7 5.1 16 5.4 0.1 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 RUS69064.1 - 0.093 13.1 10.8 0.23 11.8 0.5 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 RUS69064.1 - 0.098 12.9 8.5 0.19 12.0 3.7 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 RUS69064.1 - 0.14 12.5 10.7 1 9.7 1.8 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 RUS69064.1 - 0.16 11.8 6.4 3.4 7.6 0.2 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 RUS69064.1 - 0.18 12.2 8.4 3 8.4 0.5 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Elf1 PF05129.13 RUS69064.1 - 0.28 11.3 7.3 0.63 10.1 4.1 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.6 RUS69064.1 - 1.2 9.1 7.0 4 7.4 0.2 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 RUS69065.1 - 2.3e-33 112.8 98.4 5.5e-05 23.4 1.0 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69065.1 - 4.8e-31 104.7 95.0 0.00068 20.3 1.7 11.3 11 0 0 11 11 11 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS69065.1 - 1.5e-20 72.6 95.7 2.8e-05 24.3 0.7 11.6 11 1 1 12 12 12 9 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS69065.1 - 1e-06 28.8 58.0 0.024 14.9 0.2 11.1 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS69065.1 - 5.8e-06 26.5 64.2 0.0037 17.6 0.6 10.8 11 0 0 11 11 11 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS69065.1 - 0.00019 21.6 16.2 0.003 17.8 4.2 6.5 4 1 2 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS69065.1 - 0.00031 21.4 44.3 0.62 10.8 10.5 7.5 1 1 5 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 RUS69065.1 - 0.00047 19.9 0.3 0.00047 19.9 0.3 10.7 11 2 0 11 11 8 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS69065.1 - 0.0077 16.2 1.6 0.0077 16.2 1.6 12.4 12 2 0 12 12 12 5 C2H2-type zinc finger zf-C2H2_7 PF15269.6 RUS69065.1 - 0.01 15.9 0.4 0.01 15.9 0.4 4.7 3 2 1 5 5 5 0 Zinc-finger Zn_ribbon_SprT PF17283.2 RUS69065.1 - 0.02 14.8 3.2 0.02 14.8 3.2 7.5 7 2 2 9 9 8 0 SprT-like zinc ribbon domain DUF2502 PF10697.9 RUS69065.1 - 0.041 14.2 0.3 0.1 12.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) zf-CHCC PF10276.9 RUS69065.1 - 0.071 13.2 23.8 0.094 12.8 0.1 7.0 8 0 0 8 8 8 0 Zinc-finger domain DUF1640 PF07798.11 RUS69065.1 - 0.14 12.2 0.7 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) zinc_ribbon_15 PF17032.5 RUS69065.1 - 0.14 12.9 38.9 0.56 11.0 1.1 5.9 2 1 3 5 5 5 0 zinc-ribbon family Ribosomal_L31 PF01197.18 RUS69065.1 - 0.17 12.2 12.3 0.055 13.7 2.7 3.9 2 1 1 3 3 3 0 Ribosomal protein L31 HypA PF01155.19 RUS69065.1 - 0.42 10.7 34.5 0.2 11.7 3.0 5.4 1 1 2 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 RUS69065.1 - 0.62 9.7 0.0 0.62 9.7 0.0 10.1 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger RNA_POL_M_15KD PF02150.16 RUS69065.1 - 0.97 9.4 0.1 0.97 9.4 0.1 7.3 8 0 0 8 8 7 0 RNA polymerases M/15 Kd subunit zf-C2H2_2 PF12756.7 RUS69065.1 - 2.5 8.5 62.9 2.8 8.3 1.0 9.2 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 RUS69065.1 - 4.2 7.5 47.7 0.84 9.7 3.5 6.9 2 2 4 6 6 6 0 Transcription elongation factor Elf1 like Tctex-1 PF03645.13 RUS69066.1 - 1.7e-19 70.0 0.1 2.6e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Tctex-1 family PBP_dimer PF03717.15 RUS69067.1 - 1.1 9.6 8.6 39 4.5 0.1 5.0 3 3 1 4 4 4 0 Penicillin-binding Protein dimerisation domain Arf PF00025.21 RUS69068.1 - 3.2e-43 147.2 0.0 4.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS69068.1 - 1.3e-11 44.8 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS69068.1 - 1e-09 38.1 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RUS69068.1 - 1.5e-08 34.4 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS69068.1 - 2.2e-05 23.9 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ran_BP1 PF00638.18 RUS69069.1 - 1.6e-47 160.7 0.2 2.8e-47 160.0 0.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RUS69069.1 - 0.00068 19.6 0.1 0.0021 18.0 0.1 1.7 1 1 0 1 1 1 1 WH1 domain Arylsulfotran_2 PF14269.6 RUS69069.1 - 0.0098 15.3 0.1 2.4 7.5 0.4 2.1 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) TFIIS_C PF01096.18 RUS69069.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) TRAPP PF04051.16 RUS69070.1 - 2.3e-46 157.1 0.2 2.7e-46 156.9 0.2 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2152 PF10222.9 RUS69070.1 - 0.072 11.4 0.0 0.087 11.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) DED PF01335.21 RUS69070.1 - 0.11 12.8 0.4 1.1 9.6 0.0 2.5 2 1 1 3 3 3 0 Death effector domain dCache_1 PF02743.18 RUS69071.1 - 0.17 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Cache domain DUF4573 PF15140.6 RUS69073.1 - 7.8e-07 29.1 0.0 0.17 11.7 0.0 3.9 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) Transposase_1 PF01359.18 RUS69074.1 - 1.5e-19 69.6 0.0 2.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) WAPL PF07814.13 RUS69074.1 - 1e-08 34.4 0.0 1.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DDE_3 PF13358.6 RUS69074.1 - 3.7e-07 30.0 0.0 4.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Aminotran_1_2 PF00155.21 RUS69075.1 - 8.6e-70 235.7 0.0 9.7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 RUS69075.1 - 2.8e-05 22.9 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 RUS69075.1 - 0.0015 17.9 0.1 0.0034 16.7 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RUS69075.1 - 0.002 17.2 0.3 0.0035 16.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Flg_hook PF02120.16 RUS69075.1 - 0.045 13.6 0.1 0.52 10.2 0.1 2.6 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Enolase_C PF00113.22 RUS69076.1 - 2.6e-133 443.8 0.1 3e-133 443.6 0.1 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 RUS69076.1 - 5.3e-06 26.2 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RUS69076.1 - 0.0027 16.9 0.3 0.0055 15.9 0.3 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus KH_1 PF00013.29 RUS69077.1 - 1.4e-07 31.3 1.7 2.2e-07 30.6 0.6 1.9 2 0 0 2 2 2 1 KH domain RNase_PH_C PF03725.15 RUS69077.1 - 3.3e-07 30.2 3.8 2.2e-06 27.6 0.7 3.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 Transpeptidase PF00905.22 RUS69077.1 - 7.2e-06 25.4 1.8 0.014 14.6 0.0 2.5 2 1 1 3 3 3 2 Penicillin binding protein transpeptidase domain KH_2 PF07650.17 RUS69077.1 - 0.0011 18.7 3.9 0.0054 16.5 3.9 2.1 1 1 0 1 1 1 1 KH domain sCache_2 PF17200.4 RUS69077.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Single Cache domain 2 Methyltransf_5 PF01795.19 RUS69078.1 - 1.8e-88 297.0 0.0 2e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family GCD14 PF08704.10 RUS69078.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 RUS69078.1 - 0.0013 19.4 0.0 0.005 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS69078.1 - 0.0017 18.1 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain rRNA_methylase PF06962.12 RUS69078.1 - 0.17 11.9 0.1 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Putative rRNA methylase AICARFT_IMPCHas PF01808.18 RUS69080.1 - 3.3e-117 391.2 0.5 5.7e-117 390.4 0.5 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Aldedh PF00171.22 RUS69080.1 - 2.3e-79 267.1 1.4 2.3e-79 267.1 1.4 1.7 2 0 0 2 2 2 1 Aldehyde dehydrogenase family MGS PF02142.22 RUS69080.1 - 5.6e-26 90.6 0.1 1.9e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 MGS-like domain DUF1487 PF07368.11 RUS69080.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) tRNA_Me_trans PF03054.16 RUS69081.1 - 1.2e-67 228.3 0.2 2.2e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 tRNA methyl transferase GTP_EFTU PF00009.27 RUS69081.1 - 2.7e-37 128.2 0.2 4.7e-37 127.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 RUS69081.1 - 1.3e-36 125.0 1.6 2.4e-36 124.2 1.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 RUS69081.1 - 4e-20 71.6 0.0 8.6e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RUS69081.1 - 6.5e-12 45.7 0.7 1.9e-11 44.2 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 NAD_synthase PF02540.17 RUS69081.1 - 9.8e-07 28.1 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Ras PF00071.22 RUS69081.1 - 8.1e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Ras family ThiI PF02568.14 RUS69081.1 - 0.00036 20.2 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) RF3_C PF16658.5 RUS69081.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 RUS69081.1 - 0.002 17.6 0.1 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 RUS69081.1 - 0.0043 17.1 0.0 0.02 15.0 0.0 2.2 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 RUS69081.1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase QueC PF06508.13 RUS69081.1 - 0.0086 15.6 0.1 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 RUS69081.1 - 0.016 14.5 0.7 0.94 8.7 0.1 2.8 2 0 0 2 2 2 0 Arginosuccinate synthase 60KD_IMP PF02096.20 RUS69082.1 - 9.6e-62 207.8 8.1 1.1e-61 207.6 8.1 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein OAD_beta PF03977.13 RUS69082.1 - 0.033 13.2 0.8 0.044 12.8 0.8 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Vpu PF00558.19 RUS69082.1 - 0.038 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Vpu protein DPM3 PF08285.11 RUS69082.1 - 0.28 11.4 2.0 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PEP-utilizers_C PF02896.18 RUS69083.1 - 1.5e-80 270.4 0.0 2e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 RUS69083.1 - 3e-26 90.9 0.1 9.5e-26 89.3 0.1 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PPDK_N PF01326.19 RUS69083.1 - 3.6e-06 26.5 0.0 5.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SNARE_assoc PF09335.11 RUS69084.1 - 1.5e-13 51.2 3.2 1.5e-13 51.2 3.2 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein Tyr_Deacylase PF02580.16 RUS69085.1 - 2.4e-46 157.8 0.0 2.9e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sulfotransfer_3 PF13469.6 RUS69087.1 - 7.8e-06 26.4 0.1 0.00047 20.6 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family BTB_2 PF02214.22 RUS69088.1 - 2.7e-15 56.5 0.0 4.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kinesin_assoc PF16183.5 RUS69089.1 - 6.2e-12 46.0 1.8 6.2e-12 46.0 1.8 2.6 2 1 0 2 2 2 1 Kinesin-associated FHA PF00498.26 RUS69089.1 - 8.1e-07 29.3 0.2 1.8e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS69089.1 - 0.0017 18.6 0.0 0.0063 16.8 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 RUS69089.1 - 0.049 14.1 1.2 1 9.8 0.0 2.7 2 0 0 2 2 2 0 Kinesin protein 1B Atx10homo_assoc PF09759.9 RUS69089.1 - 1.1 9.3 4.9 7.1 6.7 0.2 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DUF4606 PF15379.6 RUS69089.1 - 1.7 8.9 6.4 8.4 6.7 3.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) DUF5082 PF16888.5 RUS69089.1 - 2.1 8.7 13.5 2.5 8.4 7.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF812 PF05667.11 RUS69089.1 - 5.1 5.8 21.8 0.34 9.7 14.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.9 RUS69089.1 - 5.3 7.0 21.4 1.2 9.1 1.2 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain TUDOR PF00567.24 RUS69090.1 - 3.2e-21 75.6 0.0 5.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 RUS69090.1 - 3.1e-13 49.4 0.1 5e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 KH domain Tudor_3 PF18115.1 RUS69090.1 - 0.0087 15.9 0.2 0.022 14.6 0.2 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain KH_4 PF13083.6 RUS69090.1 - 0.079 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 KH domain KH_2 PF07650.17 RUS69090.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 KH domain 7tm_1 PF00001.21 RUS69091.1 - 2e-05 24.1 0.4 2.2e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Kringle PF00051.18 RUS69092.1 - 1.5e-05 25.2 1.0 2.5e-05 24.5 1.0 1.4 1 0 0 1 1 1 1 Kringle domain Fasciclin PF02469.22 RUS69093.1 - 1.1e-14 54.8 0.3 1.2e-14 54.6 0.3 1.0 1 0 0 1 1 1 1 Fasciclin domain TPR_8 PF13181.6 RUS69096.1 - 3.4e-05 23.7 3.0 2.3 8.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS69096.1 - 4.7e-05 23.8 3.1 0.0074 16.8 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS69096.1 - 0.0018 18.9 0.1 0.029 15.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Prefoldin_2 PF01920.20 RUS69096.1 - 0.0026 17.7 1.2 25 4.9 0.0 3.9 4 0 0 4 4 4 0 Prefoldin subunit TPR_4 PF07721.14 RUS69096.1 - 0.017 15.7 0.0 2.8 8.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 RUS69096.1 - 0.021 15.2 0.1 0.099 13.0 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS69096.1 - 0.023 14.4 0.0 0.7 9.6 0.0 3.2 3 0 0 3 3 3 0 TPR repeat ANAPC3 PF12895.7 RUS69096.1 - 0.03 14.5 0.2 5.7 7.2 0.0 3.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RUS69096.1 - 0.067 13.6 0.0 0.75 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS69096.1 - 0.072 12.9 9.3 16 5.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS69096.1 - 0.17 11.1 7.8 0.77 8.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS69096.1 - 0.35 11.8 5.7 32 5.7 0.0 5.9 5 2 2 7 7 7 0 Tetratricopeptide repeat YgaB PF14182.6 RUS69096.1 - 0.67 10.4 2.6 1 9.8 0.3 2.5 2 0 0 2 2 2 0 YgaB-like protein TPR_12 PF13424.6 RUS69096.1 - 4.2 7.7 14.7 2.5 8.5 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat pKID PF02173.17 RUS69097.1 - 2.6e-15 55.6 3.2 6.8e-15 54.3 3.2 1.7 1 0 0 1 1 1 1 pKID domain CUE PF02845.16 RUS69098.1 - 0.00068 19.3 0.2 0.0026 17.4 0.0 2.0 2 0 0 2 2 2 1 CUE domain Acyltransferase PF01553.21 RUS69098.1 - 0.019 14.6 0.1 0.21 11.2 0.1 2.4 1 1 0 1 1 1 0 Acyltransferase RT_RNaseH_2 PF17919.1 RUS69099.1 - 1.7e-33 114.6 0.0 5.1e-33 113.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS69099.1 - 6.1e-33 113.2 0.0 1.6e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS69099.1 - 7.2e-16 58.4 0.1 1.3e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SCAN PF02023.17 RUS69099.1 - 2.3e-12 46.6 2.3 2.4e-12 46.5 0.5 2.1 2 0 0 2 2 2 1 SCAN domain zf-CCHC PF00098.23 RUS69099.1 - 3.7e-05 23.6 13.0 0.0018 18.3 3.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 RUS69099.1 - 0.038 13.7 10.5 0.22 11.3 1.5 2.7 2 0 0 2 2 2 0 Zinc knuckle TetR_C_30 PF17939.1 RUS69099.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-CCHC_2 PF13696.6 RUS69099.1 - 0.33 10.8 10.4 0.062 13.1 5.8 2.1 2 0 0 2 2 2 0 Zinc knuckle Sulfotransfer_2 PF03567.14 RUS69100.1 - 9.8e-33 114.1 0.1 1.3e-32 113.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 RUS69100.1 - 0.0037 16.2 0.0 0.0046 15.9 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 RUS69100.1 - 0.068 12.6 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 Sulfotransferase domain Acetyltransf_1 PF00583.25 RUS69101.1 - 0.00099 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS69101.1 - 0.0013 18.7 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ANAPC3 PF12895.7 RUS69102.1 - 7.9e-21 74.1 4.5 7.9e-21 74.1 4.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RUS69102.1 - 2e-06 27.5 0.7 0.0046 17.1 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS69102.1 - 3e-06 27.6 1.9 1.9e-05 25.1 0.7 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS69102.1 - 6.1e-06 26.0 3.3 0.026 14.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS69102.1 - 7.6e-05 22.9 0.1 0.29 11.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS69102.1 - 0.0002 21.1 1.7 0.56 10.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS69102.1 - 0.00037 21.1 0.0 0.61 11.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS69102.1 - 0.0062 16.5 0.2 0.19 11.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS69102.1 - 0.0091 16.6 0.1 0.47 11.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 RUS69102.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat zf-CCHC PF00098.23 RUS69106.1 - 4.1e-06 26.6 5.8 4.1e-06 26.6 5.8 2.0 3 0 0 3 3 3 1 Zinc knuckle PNMA PF14893.6 RUS69106.1 - 0.00053 19.5 4.8 0.00055 19.4 0.0 2.1 1 1 1 2 2 2 1 PNMA Retrotrans_gag PF03732.17 RUS69106.1 - 0.0019 18.4 0.1 0.0082 16.4 0.0 2.1 2 1 0 2 2 2 1 Retrotransposon gag protein Rx_N PF18052.1 RUS69106.1 - 0.0035 17.6 1.7 0.15 12.3 0.2 2.5 2 0 0 2 2 2 1 Rx N-terminal domain zf-CCHC_4 PF14392.6 RUS69106.1 - 0.036 13.8 0.8 0.036 13.8 0.8 2.6 3 0 0 3 3 3 0 Zinc knuckle EMP24_GP25L PF01105.24 RUS69106.1 - 0.08 12.9 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD zf-CCHC_2 PF13696.6 RUS69106.1 - 0.15 11.9 5.1 0.27 11.1 5.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S28e PF01200.18 RUS69109.1 - 2.3e-32 110.8 0.4 2.5e-32 110.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Cofilin_ADF PF00241.20 RUS69110.1 - 7.8e-21 74.1 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA_11 PF13086.6 RUS69110.1 - 0.17 11.6 14.1 0.28 10.9 14.1 1.3 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 RUS69110.1 - 5.5 6.0 16.4 8.2 5.4 16.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BTB PF00651.31 RUS69111.1 - 1.4e-26 92.9 4.0 2.4e-11 43.8 0.0 4.1 3 1 1 4 4 4 3 BTB/POZ domain Ras PF00071.22 RUS69111.1 - 4.8e-24 84.8 0.0 1.1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS69111.1 - 9.9e-10 38.7 0.0 2.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase BTB_3 PF16017.5 RUS69111.1 - 0.018 15.2 0.1 0.76 9.9 0.0 2.6 2 1 0 2 2 2 0 BTB/POZ domain AAA_25 PF13481.6 RUS69111.1 - 0.04 13.5 1.1 1.1 8.8 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 RUS69111.1 - 0.067 13.5 1.1 5.4 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 RUS69111.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PQ-loop PF04193.14 RUS69112.1 - 5e-29 99.8 8.1 7.3e-15 54.5 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 RUS69112.1 - 0.0021 18.0 0.2 0.0021 18.0 0.2 2.1 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Collagen PF01391.18 RUS69115.1 - 0.46 10.3 101.7 1.8e+04 -48.9 101.7 3.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4542 PF15075.6 RUS69117.1 - 0.67 10.3 6.0 0.6 10.5 2.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4542) SNF2_N PF00176.23 RUS69118.1 - 6.3e-49 166.6 0.0 1.2e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS69118.1 - 7.3e-15 55.3 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS69118.1 - 1.1e-06 28.8 2.5 2.9e-06 27.4 0.0 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RUS69118.1 - 0.00091 18.5 0.0 0.00091 18.5 0.0 3.1 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase TPR_12 PF13424.6 RUS69119.1 - 5.1e-05 23.5 0.2 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS69119.1 - 0.0018 18.3 0.1 11 6.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TM140 PF14985.6 RUS69119.1 - 0.012 15.2 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 TM140 protein family TPR_8 PF13181.6 RUS69119.1 - 0.048 13.9 0.0 1.7e+02 2.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS69119.1 - 0.14 12.0 1.0 19 5.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 RUS69120.1 - 9.7e-05 22.4 2.3 9.7e-05 22.4 2.3 1.7 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 RUS69120.1 - 0.0017 18.4 4.9 0.003 17.6 4.3 1.7 1 1 1 2 2 2 1 MYND finger CD36 PF01130.21 RUS69120.1 - 0.044 12.3 0.4 0.044 12.3 0.4 1.8 1 1 1 2 2 2 0 CD36 family zf-met PF12874.7 RUS69120.1 - 2.7 8.5 7.3 4.9 7.7 1.0 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fibrinogen_C PF00147.18 RUS69121.1 - 1.7e-40 139.1 5.7 2.7e-40 138.6 5.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MnmE_helical PF12631.7 RUS69121.1 - 0.004 17.3 0.9 0.0056 16.9 0.9 1.3 1 0 0 1 1 1 1 MnmE helical domain DUF4515 PF14988.6 RUS69121.1 - 0.13 12.1 1.4 0.19 11.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) KxDL PF10241.9 RUS69121.1 - 0.99 9.7 3.6 2.7 8.3 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein RSB_motif PF16294.5 RUS69124.1 - 4.2e-27 94.4 23.8 4.2e-27 94.4 23.8 3.0 1 1 1 2 2 2 1 RNSP1-SAP18 binding (RSB) motif Ribonuc_P_40 PF08584.11 RUS69125.1 - 0.066 12.5 6.0 0.35 10.1 0.2 3.1 3 0 0 3 3 3 0 Ribonuclease P 40kDa (Rpp40) subunit ApoO PF09769.9 RUS69125.1 - 0.51 10.3 5.5 0.21 11.5 0.4 3.0 2 1 1 3 3 3 0 Apolipoprotein O GIT_CC PF16559.5 RUS69125.1 - 5.9 6.8 19.1 5 7.1 1.1 4.9 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4573 PF15140.6 RUS69126.1 - 0.024 14.5 1.2 0.05 13.4 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) RHS_repeat PF05593.14 RUS69126.1 - 0.13 12.8 23.9 21 5.7 8.9 5.4 1 1 1 2 2 2 0 RHS Repeat Phage_Orf51 PF06194.11 RUS69126.1 - 0.39 10.8 6.5 17 5.5 0.2 3.1 1 1 2 3 3 3 0 Phage Conserved Open Reading Frame 51 Phospho_p8 PF10195.9 RUS69126.1 - 0.47 11.0 22.0 31 5.1 0.1 6.1 1 1 3 4 4 4 0 DNA-binding nuclear phosphoprotein p8 PKD_channel PF08016.12 RUS69126.1 - 3.8 6.1 3.9 7.1 5.2 0.8 1.9 1 1 1 2 2 2 0 Polycystin cation channel Ribosomal_S16 PF00886.19 RUS69127.1 - 1.4e-17 63.5 0.0 2.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Abhydrolase_1 PF00561.20 RUS69128.1 - 1.3e-26 93.9 0.1 6.4e-23 81.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS69128.1 - 4.3e-20 73.3 0.3 5.8e-20 72.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS69128.1 - 9.3e-13 48.0 0.0 3.5e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RUS69128.1 - 0.021 15.2 0.1 0.049 14.0 0.1 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DLH PF01738.18 RUS69128.1 - 0.12 11.9 0.0 6 6.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 RUS69128.1 - 0.12 11.0 0.0 0.25 10.0 0.0 1.5 2 0 0 2 2 2 0 Ndr family Glyco_hydro_35 PF01301.19 RUS69129.1 - 5.4e-88 295.6 0.0 6.1e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 RUS69129.1 - 1.3e-09 37.9 0.1 4.2e-08 32.9 0.1 2.1 1 1 0 1 1 1 1 Beta-galactosidase DUF1104 PF06518.11 RUS69130.1 - 1.2 9.6 18.2 2.6 8.5 4.9 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1104) Sulfotransfer_4 PF17784.1 RUS69130.1 - 1.9 8.3 6.3 3.4 7.4 6.1 1.7 1 1 0 1 1 1 0 Sulfotransferase domain zf-CCHC PF00098.23 RUS69131.1 - 0.00045 20.2 3.6 0.0012 18.8 3.6 1.7 1 0 0 1 1 1 1 Zinc knuckle CdiI_2 PF18593.1 RUS69131.1 - 0.14 12.8 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 CdiI immunity protein zf-CCHC_2 PF13696.6 RUS69131.1 - 0.25 11.2 3.7 0.54 10.1 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 RUS69131.1 - 0.9 9.3 4.0 1.7 8.4 4.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Fibrinogen_C PF00147.18 RUS69132.1 - 4.9e-29 101.7 0.2 6.7e-29 101.3 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain RasGEF PF00617.19 RUS69133.1 - 2.1e-56 190.9 0.6 4.3e-56 189.9 0.6 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RUS69133.1 - 1.1e-20 73.9 1.4 8.8e-19 67.7 0.3 2.9 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.23 RUS69133.1 - 2.1e-10 41.1 0.0 4.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain hnRNP_Q_AcD PF18360.1 RUS69133.1 - 0.084 12.8 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain C1_4 PF07975.12 RUS69133.1 - 0.097 12.9 1.6 6.5 7.1 0.3 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain Pheromone PF08015.11 RUS69133.1 - 9.9 7.3 12.3 1.9 9.6 1.4 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone LIM PF00412.22 RUS69134.1 - 1.8e-12 47.3 7.1 2.1e-12 47.1 7.1 1.1 1 0 0 1 1 1 1 LIM domain zf-met PF12874.7 RUS69134.1 - 0.00044 20.5 8.5 0.07 13.5 0.7 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-RING_2 PF13639.6 RUS69134.1 - 0.0023 18.3 2.9 0.64 10.4 0.3 2.2 1 1 1 2 2 2 2 Ring finger domain zf-RING_7 PF02591.15 RUS69134.1 - 0.015 15.5 0.5 0.015 15.5 0.5 2.5 2 2 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2 PF00096.26 RUS69134.1 - 0.049 14.1 5.2 3 8.5 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glyco_tran_10_N PF17039.5 RUS69134.1 - 0.2 12.1 1.7 0.23 11.9 1.7 1.2 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal zf-C2H2_jaz PF12171.8 RUS69134.1 - 0.84 10.0 10.7 8.6 6.8 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_transf_92 PF01697.27 RUS69135.1 - 8.3e-22 78.1 0.1 8.8e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS69135.1 - 0.0002 21.8 0.1 0.00029 21.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 RUS69136.1 - 1.9e-29 103.1 0.1 6.7e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS69136.1 - 0.00024 21.5 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 ETF PF01012.21 RUS69137.1 - 3.7e-49 167.1 3.7 4.4e-49 166.8 3.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TMEM208_SND2 PF05620.11 RUS69138.1 - 1.3e-49 168.3 1.7 1.7e-49 167.8 1.7 1.1 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF1084 PF06454.11 RUS69138.1 - 0.012 15.0 0.9 0.017 14.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) SNRNP27 PF08648.12 RUS69139.1 - 2.6e-05 24.2 1.8 2.6e-05 24.2 1.8 2.9 3 0 0 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins VWD PF00094.25 RUS69140.1 - 3.2e-14 53.5 0.6 9.3e-14 52.0 0.6 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 RUS69140.1 - 0.0034 17.7 14.4 0.0034 17.7 14.4 4.0 3 0 0 3 3 3 1 EGF-like domain DUF3377 PF11857.8 RUS69140.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DpnII PF04556.12 RUS69140.1 - 0.035 13.4 0.1 0.079 12.3 0.1 1.5 1 1 0 1 1 1 0 DpnII restriction endonuclease TMEM154 PF15102.6 RUS69140.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family Connexin43 PF03508.13 RUS69140.1 - 0.2 11.2 2.2 0.54 9.9 2.2 1.7 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) DUF885 PF05960.11 RUS69141.1 - 3.1e-133 446.2 0.0 3.5e-133 446.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) A_amylase_inhib PF01356.19 RUS69142.1 - 0.014 15.4 59.5 10 6.2 0.7 13.4 1 1 13 14 14 14 0 Alpha amylase inhibitor IpgD PF05925.12 RUS69142.1 - 0.35 9.4 4.4 6.4 5.2 0.3 2.3 1 1 0 2 2 2 0 Enterobacterial virulence protein IpgD GTP_cyclohydroI PF01227.22 RUS69143.1 - 6.5e-43 146.2 0.0 7.2e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RUS69143.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein MCLC PF05934.11 RUS69144.1 - 7.6e-23 81.0 7.3 2.2e-19 69.7 2.6 2.0 2 0 0 2 2 2 2 Mid-1-related chloride channel (MCLC) RT_RNaseH PF17917.1 RUS69146.1 - 9e-30 103.1 0.0 2.1e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS69146.1 - 1.9e-28 98.4 0.0 4e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS69146.1 - 1.6e-22 80.1 0.1 2.9e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS69146.1 - 2.5e-05 24.7 0.0 6.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS69146.1 - 0.0039 17.8 0.7 0.025 15.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 RUS69146.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 RUS69146.1 - 0.015 15.6 0.1 0.037 14.3 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 RUS69146.1 - 0.097 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 RUS69146.1 - 3.7 7.8 14.8 0.18 11.9 1.5 3.5 3 0 0 3 3 3 0 Zinc knuckle RE_HpaII PF09561.10 RUS69147.1 - 0.0037 16.7 0.0 1.1e+02 2.0 0.0 4.5 1 1 8 9 9 9 8 HpaII restriction endonuclease PH PF00169.29 RUS69148.1 - 1.2e-17 64.3 0.8 2.5e-17 63.3 0.2 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RUS69148.1 - 1.5e-09 38.0 1.3 2.5e-09 37.3 0.6 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 RUS69148.1 - 7.6e-05 23.1 7.6 0.0026 18.2 4.5 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 RUS69148.1 - 0.00014 22.1 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain HlyD_D23 PF16576.5 RUS69148.1 - 0.0035 16.6 0.5 0.0068 15.6 0.5 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion XK-related PF09815.9 RUS69149.1 - 4.4e-75 252.9 30.9 5.9e-75 252.4 30.9 1.2 1 0 0 1 1 1 1 XK-related protein BSD PF03909.17 RUS69150.1 - 1.2e-15 57.3 0.3 1.2e-15 57.3 0.3 2.0 2 0 0 2 2 2 1 BSD domain 2OG-FeII_Oxy PF03171.20 RUS69151.1 - 5.2e-15 55.8 0.0 5.9e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily S-AdoMet_synt_C PF02773.16 RUS69152.1 - 2.9e-70 234.6 0.7 5.7e-69 230.4 0.0 2.3 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RUS69152.1 - 2e-44 150.7 0.1 8.1e-44 148.7 0.0 2.1 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RUS69152.1 - 7.6e-42 142.0 1.1 1.4e-41 141.2 0.1 2.0 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain HSP90 PF00183.18 RUS69153.1 - 8.3e-132 440.7 20.6 1.8e-130 436.3 20.2 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 RUS69153.1 - 1.5e-15 57.2 1.9 4.3e-15 55.8 1.9 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS69153.1 - 2.9e-13 50.3 0.7 6.9e-13 49.1 0.6 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_tau_5 PF12170.8 RUS69153.1 - 0.05 13.6 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Med29 PF11568.8 RUS69153.1 - 0.067 13.4 1.3 0.22 11.8 0.4 2.3 2 0 0 2 2 2 0 Mediator complex subunit 29 Med11 PF10280.9 RUS69153.1 - 0.073 13.5 2.5 0.22 12.0 0.8 2.7 2 1 0 2 2 2 0 Mediator complex protein DUF4286 PF14114.6 RUS69153.1 - 0.3 11.6 0.0 0.3 11.6 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4286) DHFR_1 PF00186.19 RUS69154.1 - 3.5e-60 202.4 0.4 3.9e-60 202.2 0.4 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Met_gamma_lyase PF06838.11 RUS69154.1 - 0.022 13.3 0.1 0.025 13.1 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Imm26 PF15428.6 RUS69154.1 - 0.1 12.8 1.7 0.29 11.4 1.2 2.1 1 1 1 2 2 2 0 Immunity protein 26 Ribosomal_S2 PF00318.20 RUS69155.1 - 2e-74 249.5 3.0 1.7e-43 148.3 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Peripla_BP_1 PF00532.21 RUS69155.1 - 0.019 14.4 0.1 0.076 12.4 0.2 1.8 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family BRCT_3 PF18428.1 RUS69155.1 - 0.078 13.1 0.0 9.6 6.4 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ADH_zinc_N PF00107.26 RUS69155.1 - 0.19 11.7 1.5 6 6.9 0.2 2.5 1 1 0 2 2 2 0 Zinc-binding dehydrogenase EF_TS PF00889.19 RUS69156.1 - 7.9e-50 169.4 2.9 2.2e-40 138.5 0.3 2.4 2 1 1 3 3 3 2 Elongation factor TS AA_kinase PF00696.28 RUS69157.1 - 7.5e-22 78.1 0.1 8.5e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family RRF PF01765.19 RUS69158.1 - 1.1e-32 113.2 6.2 1.2e-32 113.1 6.2 1.0 1 0 0 1 1 1 1 Ribosome recycling factor DUF5401 PF17380.2 RUS69158.1 - 0.094 10.8 7.1 0.11 10.6 7.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) TBCA PF02970.16 RUS69158.1 - 0.23 11.8 7.8 0.17 12.2 6.3 1.5 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF763 PF05559.11 RUS69158.1 - 0.24 10.6 1.5 0.25 10.5 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) GTP_EFTU PF00009.27 RUS69159.1 - 1.4e-58 197.7 0.1 2.6e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RUS69159.1 - 1.8e-43 147.2 1.7 4.6e-43 145.9 0.5 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV Ribosomal_L14 PF00238.19 RUS69159.1 - 3.7e-35 120.7 0.8 3.7e-35 120.7 0.8 2.3 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e EFG_II PF14492.6 RUS69159.1 - 7.2e-35 118.9 0.0 1.8e-34 117.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Ribosomal_S5_C PF03719.15 RUS69159.1 - 7.6e-29 99.0 0.4 1.7e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S7 PF00177.21 RUS69159.1 - 1.3e-22 80.0 1.7 1.3e-22 80.0 1.7 2.3 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e GTP_EFTU_D2 PF03144.25 RUS69159.1 - 1.9e-18 66.6 3.8 4.2e-18 65.5 0.9 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ribosomal_L2_C PF03947.18 RUS69159.1 - 2.6e-17 63.2 1.5 1.1e-16 61.1 1.5 2.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain EFG_C PF00679.24 RUS69159.1 - 1.2e-12 47.7 0.0 1.2e-11 44.5 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G C-terminus Ribosomal_L23 PF00276.20 RUS69159.1 - 8.7e-12 45.2 2.3 9.3e-12 45.2 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_S3_C PF00189.20 RUS69159.1 - 2.6e-10 40.7 0.8 1.2e-09 38.6 0.8 2.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain RF3_C PF16658.5 RUS69159.1 - 2.9e-06 27.1 0.6 2.9e-05 23.9 0.1 2.6 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Ribosomal_L16 PF00252.18 RUS69159.1 - 8.4e-06 25.8 0.2 8.4e-06 25.8 0.2 2.7 3 0 0 3 3 3 1 Ribosomal protein L16p/L10e Ribosomal_L3 PF00297.22 RUS69159.1 - 1.9e-05 23.8 2.0 4.2e-05 22.7 1.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L3 Ribosomal_L6 PF00347.23 RUS69159.1 - 3.8e-05 24.3 4.0 0.0011 19.6 0.0 4.0 3 0 0 3 3 3 1 Ribosomal protein L6 Rad52_Rad22 PF04098.15 RUS69159.1 - 0.14 12.1 0.4 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Spc7 PF08317.11 RUS69160.1 - 0.00017 20.6 124.0 0.0043 16.0 28.1 5.3 1 1 4 5 5 5 3 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 RUS69160.1 - 0.00086 19.5 12.2 0.00086 19.5 12.2 8.0 2 2 5 8 8 8 1 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 RUS69160.1 - 0.0024 18.3 110.4 0.022 15.2 38.9 5.6 1 1 3 4 4 3 2 Fez1 TFA2_Winged_2 PF18121.1 RUS69160.1 - 0.005 16.5 10.2 0.55 10.0 0.6 4.8 4 0 0 4 4 4 2 TFA2 Winged helix domain 2 XhlA PF10779.9 RUS69160.1 - 0.0053 16.9 3.1 0.0053 16.9 3.1 9.7 5 3 6 11 11 10 1 Haemolysin XhlA DHR10 PF18595.1 RUS69160.1 - 0.018 15.1 7.6 0.018 15.1 7.6 7.8 2 2 4 7 7 7 0 Designed helical repeat protein 10 domain Filament PF00038.21 RUS69160.1 - 0.03 13.9 98.8 0.45 10.0 47.2 5.0 1 1 3 4 4 4 0 Intermediate filament protein DUF211 PF02680.14 RUS69160.1 - 0.076 13.2 13.2 2.9 8.1 0.2 5.7 3 2 1 5 5 5 0 Uncharacterized ArCR, COG1888 Methyltransf_24 PF13578.6 RUS69160.1 - 0.22 12.5 8.2 2.2 9.3 0.1 3.6 3 1 0 3 3 3 0 Methyltransferase domain ATG16 PF08614.11 RUS69160.1 - 1.6 8.9 122.3 0.37 11.0 32.8 6.7 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 RUS69160.1 - 2.7 8.0 136.6 0.031 14.3 20.0 6.5 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCB1 PF12046.8 RUS69160.1 - 3 7.1 11.2 0.69 9.2 1.0 3.5 3 1 0 3 3 3 0 Cofactor assembly of complex C subunit B GAS PF13851.6 RUS69160.1 - 4 6.7 124.6 0.29 10.4 20.0 5.6 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DUF5302 PF17227.2 RUS69160.1 - 5.7 8.0 5.6 13 6.9 0.2 3.6 3 0 0 3 3 2 0 Family of unknown function (DUF5302) Tropomyosin PF00261.20 RUS69161.1 - 1.5e-05 24.5 41.8 1.5e-05 24.5 41.8 9.8 1 1 8 9 9 3 1 Tropomyosin CENP-F_leu_zip PF10473.9 RUS69161.1 - 1.6e-05 24.9 29.0 1.6e-05 24.9 29.0 13.6 2 2 13 15 15 15 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 RUS69161.1 - 4.2e-05 23.6 4.8 4.2e-05 23.6 4.8 15.0 4 2 14 19 19 19 4 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 RUS69161.1 - 0.0012 16.9 10.5 0.0012 16.9 10.5 8.8 1 1 6 7 7 5 2 V-type ATPase 116kDa subunit family ADIP PF11559.8 RUS69161.1 - 0.0055 16.8 13.5 0.0055 16.8 13.5 16.9 1 1 14 17 17 17 1 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 RUS69161.1 - 0.0057 16.8 22.0 0.0057 16.8 22.0 12.6 1 1 11 13 13 11 3 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 RUS69161.1 - 0.0059 17.1 217.4 0.043 14.3 17.3 10.5 2 2 7 10 10 10 5 Fez1 Tropomyosin_1 PF12718.7 RUS69161.1 - 0.0062 16.7 8.1 0.0062 16.7 8.1 13.0 2 2 12 14 14 10 5 Tropomyosin like DUF4201 PF13870.6 RUS69161.1 - 0.0067 16.2 10.6 0.0067 16.2 10.6 12.7 1 1 10 13 13 13 4 Domain of unknown function (DUF4201) DUF1137 PF06587.11 RUS69161.1 - 0.063 13.3 2.3 1.4 9.0 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) DicB PF05358.11 RUS69161.1 - 0.12 12.6 0.7 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 DicB protein DUF5582 PF17819.1 RUS69162.1 - 0.00052 20.5 1.1 0.002 18.6 0.2 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5582) Dpy-30 PF05186.13 RUS69162.1 - 0.00095 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif NTR2 PF15458.6 RUS69162.1 - 0.032 13.8 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Lectin_C PF00059.21 RUS69163.1 - 2.6e-11 44.2 0.0 4.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain Myosin_tail_1 PF01576.19 RUS69164.1 - 5.2e-10 37.8 28.1 5.2e-10 37.8 28.1 3.0 2 1 1 3 3 3 1 Myosin tail TolA_bind_tri PF16331.5 RUS69164.1 - 0.00064 19.8 0.4 0.00064 19.8 0.4 6.0 3 2 2 5 5 5 1 TolA binding protein trimerisation Fez1 PF06818.15 RUS69164.1 - 0.001 19.6 53.7 0.016 15.7 23.8 3.4 1 1 3 4 4 4 2 Fez1 BST2 PF16716.5 RUS69164.1 - 0.04 14.5 3.0 0.04 14.5 3.0 5.3 3 1 0 4 4 4 0 Bone marrow stromal antigen 2 DUF4201 PF13870.6 RUS69164.1 - 0.26 11.0 49.2 0.24 11.1 6.7 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) Filament PF00038.21 RUS69164.1 - 0.32 10.5 46.9 0.24 10.9 14.0 3.4 2 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 RUS69164.1 - 0.54 10.3 28.5 2.6 8.1 0.9 4.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Shugoshin_N PF07558.11 RUS69164.1 - 0.81 9.6 9.3 2.3 8.2 0.2 4.2 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Atx10homo_assoc PF09759.9 RUS69164.1 - 1.5 8.9 6.4 20 5.3 1.1 3.3 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DUF2046 PF09755.9 RUS69164.1 - 3.4 6.8 47.0 0.05 12.8 12.6 4.1 2 2 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Bacillus_HBL PF05791.11 RUS69164.1 - 7.4 6.4 18.2 0.54 10.1 3.1 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 RUS69164.1 - 9.7 6.6 58.7 0.52 10.7 3.1 5.1 1 1 5 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region 2OG-FeII_Oxy_3 PF13640.6 RUS69165.1 - 1e-14 55.2 0.0 2.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAM117 PF15388.6 RUS69166.1 - 6.6e-38 130.9 8.0 6.6e-38 130.9 8.0 2.0 2 0 0 2 2 2 1 Protein Family FAM117 Mic1 PF07035.12 RUS69167.1 - 6.1e-40 136.5 0.2 7.1e-40 136.3 0.2 1.0 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Frigida PF07899.11 RUS69167.1 - 0.016 14.5 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Frigida-like protein ELYS PF13934.6 RUS69167.1 - 0.12 12.4 0.3 0.19 11.6 0.2 1.5 1 1 0 1 1 1 0 Nuclear pore complex assembly LRR_8 PF13855.6 RUS69168.1 - 2.2e-60 200.3 97.8 1.1e-11 44.3 8.8 10.6 6 3 6 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 RUS69168.1 - 1.2e-25 89.1 86.8 1.3e-05 25.4 6.5 13.0 7 4 6 15 15 15 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS69168.1 - 1e-10 41.4 25.6 0.0002 20.9 0.5 6.0 4 2 1 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 RUS69168.1 - 4.5e-08 32.6 60.9 0.36 11.6 1.8 14.5 15 1 0 15 15 15 4 Leucine Rich Repeat LRR_6 PF13516.6 RUS69168.1 - 0.015 15.3 66.9 3.1 8.1 3.0 13.5 14 0 0 14 14 14 0 Leucine Rich repeat LRRNT PF01462.18 RUS69168.1 - 0.04 13.6 1.9 0.11 12.1 1.9 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Acyl-ACP_TE PF01643.17 RUS69170.1 - 1.9e-08 33.9 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS69170.1 - 0.0062 17.0 0.1 0.36 11.3 0.1 2.4 2 0 0 2 2 2 1 Thioesterase-like superfamily DS PF01916.17 RUS69171.1 - 4.8e-80 268.9 0.0 5.7e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Ank_2 PF12796.7 RUS69172.1 - 3.2e-128 418.6 57.1 3e-17 63.0 0.2 11.1 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69172.1 - 2.8e-120 391.3 43.7 9.1e-14 51.6 0.1 17.8 8 4 9 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 RUS69172.1 - 1.8e-101 328.5 72.4 4.6e-06 26.8 0.1 23.5 24 0 0 24 24 24 21 Ankyrin repeat Ank_5 PF13857.6 RUS69172.1 - 1.1e-95 312.4 57.0 1.7e-10 41.0 0.2 19.3 6 4 14 20 20 20 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS69172.1 - 1.7e-92 292.2 47.7 1.8e-05 24.8 0.0 24.0 24 0 0 24 24 24 20 Ankyrin repeat DUF5492 PF17596.2 RUS69172.1 - 0.039 14.3 2.0 22 5.5 0.0 4.4 4 1 0 4 4 4 0 Family of unknown function (DUF5492) Prok-RING_1 PF14446.6 RUS69172.1 - 0.23 11.4 1.9 24 4.9 0.2 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Ank_4 PF13637.6 RUS69173.1 - 7.8e-25 86.9 7.3 4.9e-12 46.1 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS69173.1 - 8.4e-24 83.3 5.3 3.4e-12 46.3 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS69173.1 - 5.4e-22 78.2 0.6 4.5e-16 59.2 1.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS69173.1 - 3.8e-20 69.8 1.1 8.1e-05 22.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RUS69173.1 - 1e-18 66.9 11.8 4.1e-05 23.8 0.2 4.9 5 1 0 5 5 5 4 Ankyrin repeat Glutaredoxin PF00462.24 RUS69175.1 - 1e-11 44.9 0.5 2.2e-11 43.8 0.5 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 RUS69175.1 - 2e-10 41.0 0.1 6.4e-10 39.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS69175.1 - 2.7e-07 30.8 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS69175.1 - 6.6e-06 26.4 0.1 2.9e-05 24.3 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS69175.1 - 8.9e-05 22.4 0.0 0.00023 21.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS69175.1 - 0.0014 19.3 0.0 0.089 13.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain DUF836 PF05768.14 RUS69175.1 - 0.0027 18.1 0.1 0.0053 17.1 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_C PF00043.25 RUS69175.1 - 0.0065 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS69175.1 - 0.0079 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RUS69175.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MYEOV2 PF15004.6 RUS69176.1 - 5e-32 110.1 5.4 5.5e-32 110.0 5.4 1.0 1 0 0 1 1 1 1 Myeloma-overexpressed-like Peptidase_S9 PF00326.21 RUS69177.1 - 9.2e-44 149.5 0.0 1.4e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 RUS69177.1 - 3.4e-06 26.8 0.0 7.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Str_synth PF03088.16 RUS69177.1 - 0.001 19.2 0.0 0.011 15.8 0.0 2.7 3 0 0 3 3 3 1 Strictosidine synthase Hydrolase_4 PF12146.8 RUS69177.1 - 0.002 17.4 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 RUS69177.1 - 0.0034 17.3 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 RUS69177.1 - 0.0058 15.3 0.0 0.064 11.9 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 RUS69177.1 - 0.011 15.4 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 RUS69177.1 - 0.011 15.6 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold PBP PF01161.20 RUS69177.1 - 0.045 14.1 0.1 0.09 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Pentaxin PF00354.17 RUS69177.1 - 0.1 12.3 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Pentaxin family MCLC PF05934.11 RUS69178.1 - 1.3e-06 27.5 0.1 1.8e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) DUF3397 PF11877.8 RUS69178.1 - 0.053 13.7 1.0 0.053 13.7 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) PMP1_2 PF08114.11 RUS69178.1 - 0.078 12.7 1.7 0.96 9.2 0.0 2.6 3 0 0 3 3 3 0 ATPase proteolipid family TMEM100 PF16311.5 RUS69178.1 - 0.092 12.3 0.1 0.092 12.3 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 Peptidase_A8 PF01252.18 RUS69178.1 - 0.4 10.9 3.8 20 5.4 0.5 3.0 3 0 0 3 3 3 0 Signal peptidase (SPase) II DUF3021 PF11457.8 RUS69178.1 - 0.51 10.7 6.9 0.33 11.3 3.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) DUF2663 PF10864.8 RUS69178.1 - 1.4 9.3 3.6 0.85 10.0 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Glycos_transf_4 PF00953.21 RUS69178.1 - 2.1 8.3 6.0 2 8.4 2.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 4 zf-C2H2 PF00096.26 RUS69179.1 - 7.6e-59 193.0 103.6 7e-05 23.1 2.4 15.7 16 0 0 16 16 16 14 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS69179.1 - 1.9e-55 182.9 89.0 3.1e-07 30.5 0.2 15.6 15 0 0 15 15 15 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS69179.1 - 8.4e-51 166.2 97.8 0.00038 21.0 0.6 15.4 15 0 0 15 15 15 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS69179.1 - 4.5e-28 96.9 57.9 0.011 16.0 1.4 14.7 15 0 0 15 15 15 11 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS69179.1 - 7.9e-11 41.5 66.3 0.066 13.0 0.0 13.4 14 0 0 14 14 14 8 zinc-finger C2H2-type BolA PF01722.18 RUS69179.1 - 6e-09 36.1 14.3 0.13 12.6 0.1 7.7 6 2 3 9 9 9 3 BolA-like protein zf-met PF12874.7 RUS69179.1 - 2.4e-07 30.9 69.4 0.0031 17.8 1.4 13.3 15 0 0 15 15 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS69179.1 - 0.00016 21.6 92.7 0.022 14.7 0.4 15.4 15 1 1 16 16 16 6 C2H2-type zinc finger DUF4764 PF15961.5 RUS69179.1 - 0.00095 18.0 0.4 0.00095 18.0 0.4 5.8 3 1 3 6 6 6 2 Domain of unknown function (DUF4764) zf-C2H2_8 PF15909.5 RUS69179.1 - 0.0023 18.2 44.4 1 9.7 3.2 6.9 3 2 4 7 7 7 5 C2H2-type zinc ribbon zf-Di19 PF05605.12 RUS69179.1 - 0.0036 17.6 70.7 0.0092 16.3 5.0 9.4 4 4 6 11 11 11 6 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 RUS69179.1 - 0.017 14.7 32.1 2 8.1 0.0 9.3 7 3 2 9 9 9 0 MYST family zinc finger domain CxC7 PF18866.1 RUS69179.1 - 3.8 7.7 29.2 3 8.1 0.1 8.0 6 3 4 10 10 10 0 CxC7 like cysteine cluster associated with KDZ transposases FtsX PF02687.21 RUS69180.1 - 0.24 11.9 4.6 0.066 13.7 1.2 1.7 2 0 0 2 2 2 0 FtsX-like permease family ODC_AZ PF02100.17 RUS69181.1 - 3.8e-20 72.0 0.0 6.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme ATP-synt_ab PF00006.25 RUS69182.1 - 3e-15 56.4 0.1 3.9e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mor PF08765.11 RUS69182.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Mor transcription activator family Glu_synthase PF01645.17 RUS69183.1 - 2.9e-48 164.9 0.6 3.7e-48 164.5 0.6 1.0 1 0 0 1 1 1 1 Conserved region in glutamate synthase MgsA_C PF12002.8 RUS69183.1 - 1.2e-10 41.5 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal CPSase_L_D2 PF02786.17 RUS69184.1 - 2.9e-77 258.9 0.0 4.3e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RUS69184.1 - 1.2e-46 157.7 0.1 2.8e-46 156.6 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RUS69184.1 - 6.8e-41 138.7 0.0 2.1e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 RUS69184.1 - 3e-11 43.3 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RUS69184.1 - 1.3e-07 31.4 0.1 2.7e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 RUS69184.1 - 1.5e-06 28.3 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 RUS69184.1 - 0.094 12.9 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Biotin_lipoyl PF00364.22 RUS69185.1 - 9.3e-24 83.1 0.6 4e-23 81.0 0.3 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RUS69185.1 - 6.8e-10 38.6 0.3 0.00062 19.5 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like GCV_H PF01597.19 RUS69185.1 - 0.0059 16.5 1.4 0.024 14.5 0.2 2.0 2 0 0 2 2 2 1 Glycine cleavage H-protein QRPTase_N PF02749.16 RUS69185.1 - 0.14 12.2 0.1 6.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain YqfD PF06898.11 RUS69185.1 - 0.26 10.1 1.7 3.1 6.5 0.1 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD RrnaAD PF00398.20 RUS69186.1 - 3.9e-59 199.9 0.7 4.3e-59 199.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 RUS69186.1 - 0.1 13.4 0.0 0.24 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RUS69186.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 RUS69186.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_1d PF00750.19 RUS69187.1 - 6.6e-80 268.7 0.0 9.2e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RUS69187.1 - 2.9e-24 85.5 0.2 5.8e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RUS69187.1 - 6.4e-16 58.7 0.3 1.9e-15 57.2 0.3 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 RUS69187.1 - 0.0089 14.8 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RUS69187.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain AAA PF00004.29 RUS69188.1 - 8.7e-46 155.6 0.0 1.5e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS69188.1 - 3.2e-14 52.5 0.0 6.6e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Peptidase_M41 PF01434.18 RUS69188.1 - 6.8e-09 35.8 0.6 1.3e-08 34.9 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M41 TIP49 PF06068.13 RUS69188.1 - 3.1e-07 29.9 0.1 5.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 RUS69188.1 - 1.6e-05 24.9 0.1 0.00017 21.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS69188.1 - 7.5e-05 22.5 0.0 0.00087 19.1 0.0 2.6 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RUS69188.1 - 0.00061 20.2 0.1 0.017 15.5 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 RUS69188.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RUS69188.1 - 0.0017 17.8 1.2 0.0067 15.8 0.3 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RUS69188.1 - 0.0019 18.4 0.0 0.0032 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS69188.1 - 0.0024 18.2 0.1 0.061 13.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RUS69188.1 - 0.0041 16.8 0.1 0.094 12.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 RUS69188.1 - 0.017 15.3 0.0 0.067 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 RUS69188.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 RUS69188.1 - 0.026 15.0 0.0 0.071 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RUS69188.1 - 0.027 14.5 0.0 0.09 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 RUS69188.1 - 0.054 13.0 0.2 0.098 12.1 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 RUS69188.1 - 0.058 12.9 0.2 0.17 11.4 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RUS69188.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RUS69188.1 - 0.088 13.3 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 RUS69188.1 - 0.094 12.6 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RUS69188.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RUS69188.1 - 0.13 11.9 0.8 0.86 9.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain TsaE PF02367.17 RUS69188.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Nif11 PF07862.11 RUS69189.1 - 0.085 13.2 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 Nif11 domain MFS_1 PF07690.16 RUS69190.1 - 1.1e-18 67.3 3.3 1.2e-18 67.2 3.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS69190.1 - 4.2e-09 35.8 4.4 4.5e-09 35.7 4.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 RUS69190.1 - 0.00022 20.3 0.5 0.00023 20.2 0.5 1.2 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 RUS69190.1 - 0.0017 17.3 1.6 0.0022 16.9 1.6 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 RUS69190.1 - 0.0037 16.6 2.8 0.0064 15.8 2.9 1.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 RUS69190.1 - 0.02 13.3 0.5 0.023 13.1 0.5 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector AAA_12 PF13087.6 RUS69191.1 - 2e-41 141.8 0.2 5.3e-41 140.4 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS69191.1 - 7.7e-25 88.2 9.4 1.3e-13 51.4 4.2 3.5 3 1 0 4 4 4 2 AAA domain AAA_19 PF13245.6 RUS69191.1 - 5.2e-09 36.6 0.4 1.3e-05 25.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RUS69191.1 - 6.7e-08 32.5 0.3 6.8e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 RUS69191.1 - 0.0001 21.7 0.0 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 RUS69191.1 - 0.00022 21.1 7.1 0.0071 16.1 0.0 4.5 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 RUS69191.1 - 0.0033 17.4 0.0 0.016 15.2 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RUS69191.1 - 0.005 16.6 1.1 0.13 12.0 0.0 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS69191.1 - 0.007 16.7 1.4 0.099 12.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 RUS69191.1 - 0.0094 15.4 1.0 0.026 14.0 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein DUF5320 PF17253.2 RUS69191.1 - 0.88 10.7 5.3 16 6.6 0.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Pkinase_Tyr PF07714.17 RUS69192.1 - 3.9e-79 265.6 0.0 5.5e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS69192.1 - 3.7e-43 147.8 0.0 5.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RUS69192.1 - 0.019 14.3 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS69192.1 - 0.02 13.8 0.1 0.031 13.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 RUS69192.1 - 0.17 11.5 0.2 0.54 9.8 0.1 1.7 1 1 0 1 1 1 0 RIO1 family TRAM_LAG1_CLN8 PF03798.16 RUS69193.1 - 2.4e-19 69.9 15.2 2.4e-19 69.9 15.2 1.4 2 0 0 2 2 2 1 TLC domain RNase_PH PF01138.21 RUS69195.1 - 3e-27 95.7 0.0 5.5e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS69195.1 - 6.7e-11 42.1 0.2 1.1e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BrnA_antitoxin PF14384.6 RUS69195.1 - 0.086 13.3 0.3 0.6 10.7 0.1 2.2 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system Aminotran_1_2 PF00155.21 RUS69196.1 - 1.6e-42 146.0 0.0 1.9e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RUS69196.1 - 4.3e-05 23.0 0.1 6.3e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RUS69196.1 - 0.00033 19.3 0.0 0.00062 18.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RUS69196.1 - 0.0036 16.3 0.0 0.0067 15.4 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Pilin PF00114.19 RUS69197.1 - 7.7e-10 39.7 6.6 9.2e-10 39.4 6.6 1.1 1 0 0 1 1 1 1 Pilin (bacterial filament) Chorion_1 PF01723.16 RUS69197.1 - 0.022 14.8 11.9 0.025 14.5 11.9 1.1 1 0 0 1 1 1 0 Chorion protein FtsJ PF01728.19 RUS69198.1 - 1.5e-54 184.8 0.0 1.7e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 RUS69198.1 - 0.00037 20.3 0.2 1.2 8.9 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RUS69198.1 - 0.0039 16.8 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Asn_synthase PF00733.21 RUS69199.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF3883 PF13020.6 RUS69201.1 - 7.7e-14 51.5 0.0 1.5e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) NPV_P10 PF05531.12 RUS69202.1 - 0.015 15.7 1.1 2.7 8.5 0.3 3.7 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3439 PF11921.8 RUS69202.1 - 0.021 14.8 6.0 0.04 13.9 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NAM-associated PF14303.6 RUS69202.1 - 0.075 13.7 1.0 0.81 10.4 1.0 2.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Spectrin PF00435.21 RUS69202.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.8 3 1 1 4 4 4 0 Spectrin repeat HMMR_N PF15905.5 RUS69202.1 - 0.37 10.2 10.3 0.02 14.4 3.5 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ABC2_membrane_3 PF12698.7 RUS69202.1 - 1.1 8.4 0.0 1.1 8.4 0.0 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein SSP160 PF06933.11 RUS69202.1 - 4.7 5.3 12.2 7.8 4.6 12.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 RUS69202.1 - 5.5 7.2 12.7 7 6.8 11.8 1.5 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Occludin_ELL PF07303.13 RUS69202.1 - 6 7.7 6.1 5 7.9 0.1 3.4 3 1 0 3 3 3 0 Occludin homology domain Archease PF01951.16 RUS69203.1 - 7.9e-44 149.3 0.6 9e-44 149.1 0.6 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) DUF2895 PF11444.8 RUS69203.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Vps52 PF04129.12 RUS69204.1 - 3.2e-164 547.4 10.1 4.3e-164 547.0 10.1 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family DNA_repr_REX1B PF14966.6 RUS69204.1 - 0.017 15.7 4.6 4.8 7.9 0.0 3.6 4 0 0 4 4 4 0 DNA repair REX1-B RGS PF00615.19 RUS69204.1 - 0.13 12.6 2.2 1.3 9.3 0.9 3.1 2 1 0 2 2 2 0 Regulator of G protein signaling domain Ribosomal_S13 PF00416.22 RUS69205.1 - 1.1e-53 181.1 4.1 1.2e-53 180.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 RUS69205.1 - 0.032 13.0 0.0 0.041 12.6 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 RUS69205.1 - 0.1 13.0 1.0 0.19 12.2 1.0 1.4 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 EF-hand_8 PF13833.6 RUS69205.1 - 0.12 12.2 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair HSP20 PF00011.21 RUS69206.1 - 3.7e-19 68.8 0.6 4.5e-19 68.5 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RUS69206.1 - 0.013 16.5 0.6 0.023 15.7 0.1 1.6 2 0 0 2 2 2 0 CS domain ArsA_HSP20 PF17886.1 RUS69206.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Cadherin_pro PF08758.11 RUS69206.1 - 0.05 13.8 0.1 0.091 12.9 0.1 1.5 1 1 0 1 1 1 0 Cadherin prodomain like HSP70 PF00012.20 RUS69207.1 - 8.1e-107 357.9 0.2 9e-107 357.7 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS69207.1 - 6.5e-11 41.6 0.1 5.5e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 RUS69207.1 - 0.026 13.8 0.9 0.14 11.4 0.1 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 RUS69207.1 - 0.41 11.1 2.3 1.2 9.6 0.3 2.6 2 1 0 2 2 2 0 Cell division protein FtsA AMP-binding PF00501.28 RUS69208.1 - 1.1e-57 195.5 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS69208.1 - 3.1e-05 24.8 0.0 8.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3046 PF11248.8 RUS69208.1 - 0.1 12.9 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) Insulin PF00049.18 RUS69209.1 - 6.5e-08 33.5 2.3 1.5e-07 32.3 2.3 1.7 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Jas PF16135.5 RUS69209.1 - 0.01 16.0 0.3 0.02 15.1 0.3 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Ins_beta PF03488.14 RUS69210.1 - 1 9.4 3.7 5 7.2 0.0 2.9 3 0 0 3 3 3 0 Nematode insulin-related peptide beta type Pyr_redox_2 PF07992.14 RUS69211.1 - 2.4e-59 201.0 3.7 3.2e-59 200.6 3.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RUS69211.1 - 2.9e-23 82.2 0.2 9.7e-23 80.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RUS69211.1 - 5.7e-17 62.0 9.3 9.6e-16 58.1 0.3 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS69211.1 - 6.3e-16 58.5 1.3 9.5e-16 57.9 1.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS69211.1 - 5.3e-08 32.4 16.4 1.5e-05 24.2 9.8 3.9 3 1 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 RUS69211.1 - 7.5e-07 28.8 2.3 2.3e-05 24.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS69211.1 - 2.8e-05 23.0 15.3 0.045 12.4 0.0 4.6 3 2 2 5 5 5 3 HI0933-like protein DAO PF01266.24 RUS69211.1 - 0.00016 21.4 11.7 0.082 12.5 1.1 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RUS69211.1 - 0.00019 20.8 9.3 0.015 14.6 0.0 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 RUS69211.1 - 0.00036 19.7 6.7 0.024 13.7 1.0 2.7 2 2 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 RUS69211.1 - 0.0077 16.4 4.2 1.9 8.8 1.4 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS69211.1 - 0.014 14.5 11.7 0.05 12.7 3.3 3.0 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 RUS69211.1 - 0.045 13.6 7.0 0.11 12.3 0.0 2.7 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 RUS69211.1 - 0.058 13.9 0.2 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain DFP PF04127.15 RUS69211.1 - 0.068 13.0 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Cauli_DNA-bind PF03310.13 RUS69211.1 - 0.075 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Pirin_C PF05726.13 RUS69211.1 - 0.095 13.1 0.0 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Pirin C-terminal cupin domain NAD_binding_7 PF13241.6 RUS69211.1 - 0.17 12.4 2.4 11 6.5 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 RUS69211.1 - 2 7.6 7.0 3.9 6.6 2.4 2.9 1 1 1 2 2 2 0 Thi4 family TatD_DNase PF01026.21 RUS69212.1 - 1.6e-32 112.9 0.1 1.8e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase Aldedh PF00171.22 RUS69213.1 - 2.6e-114 382.3 0.5 3.1e-114 382.0 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 RUS69214.1 - 9.2e-21 74.4 0.0 1.1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69214.1 - 5.1e-14 52.2 0.0 5.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS69214.1 - 0.00076 18.9 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS69214.1 - 0.0038 16.6 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RUS69215.1 - 3.2e-33 115.2 0.0 8.7e-31 107.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69215.1 - 1.1e-22 80.6 0.0 4.8e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS69215.1 - 6.9e-05 22.3 0.0 0.0024 17.3 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 RUS69215.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3117 PF11314.8 RUS69215.1 - 0.027 14.3 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) RS4NT PF08071.12 RUS69215.1 - 0.093 12.9 0.5 26 5.0 0.0 2.9 3 0 0 3 3 3 0 RS4NT (NUC023) domain DUF3862 PF12978.7 RUS69217.1 - 0.059 13.2 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) Cation_efflux PF01545.21 RUS69218.1 - 1.5e-06 28.1 1.6 1.9e-06 27.8 1.6 1.1 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.21 RUS69219.1 - 2.3e-49 167.9 13.3 2.8e-49 167.6 13.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RUS69219.1 - 0.00017 21.7 0.2 0.00031 20.8 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SUR7 PF06687.12 RUS69219.1 - 0.25 10.9 5.7 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 SUR7/PalI family NDK PF00334.19 RUS69220.1 - 2.3e-71 238.1 0.0 2.7e-38 131.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 RUS69220.1 - 0.0057 16.5 1.3 0.046 13.5 0.5 2.6 2 1 0 2 2 2 1 DUF1126 PH-like domain TEX13 PF15186.6 RUS69221.1 - 0.018 14.7 7.2 0.24 11.1 0.5 2.7 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family BBE PF08031.12 RUS69221.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like Takusan PF04822.13 RUS69221.1 - 0.67 9.9 8.0 16 5.4 3.4 3.4 2 1 0 2 2 2 0 Takusan APG6_N PF17675.1 RUS69221.1 - 6.1 7.4 11.5 10 6.6 1.3 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region MbeD_MobD PF04899.12 RUS69221.1 - 6.6 6.9 10.3 7.7 6.7 0.9 3.7 1 1 3 4 4 4 0 MbeD/MobD like AATF-Che1 PF13339.6 RUS69221.1 - 7.7 7.2 10.3 0.34 11.6 1.5 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Fibrinogen_C PF00147.18 RUS69223.1 - 6.2e-56 189.7 2.2 9.7e-56 189.0 2.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS69223.1 - 0.00088 19.2 27.2 0.03 14.2 14.5 2.9 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain KID PF02524.14 RUS69223.1 - 0.0032 17.3 0.7 0.38 11.0 0.0 2.8 2 0 0 2 2 2 1 KID repeat SlyX PF04102.12 RUS69223.1 - 0.44 11.2 8.7 2.9 8.6 1.8 3.3 1 1 1 2 2 2 0 SlyX Cas6b_C PF17262.2 RUS69223.1 - 0.51 10.5 7.8 3.9 7.6 0.1 3.1 3 1 1 4 4 4 0 Cas6b C-terminal domain NPV_P10 PF05531.12 RUS69223.1 - 0.77 10.3 11.1 0.81 10.2 3.3 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Gp-FAR-1 PF05823.12 RUS69223.1 - 1.6 9.0 11.4 1.8 8.9 2.0 2.6 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.12 RUS69223.1 - 2.2 8.3 23.6 0.21 11.6 3.2 3.7 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 RUS69223.1 - 6.3 7.2 17.1 6.9 7.0 10.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 RUS69223.1 - 7.1 6.7 14.1 2.9 7.9 4.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Focal_AT PF03623.13 RUS69223.1 - 7.6 6.5 11.8 0.22 11.5 1.0 3.2 1 1 3 4 4 4 0 Focal adhesion targeting region Occludin_ELL PF07303.13 RUS69223.1 - 8.2 7.2 10.0 4.5 8.1 4.2 2.9 2 0 0 2 2 2 0 Occludin homology domain ING PF12998.7 RUS69223.1 - 9.5 6.9 13.3 1.5 9.4 6.0 3.1 1 1 3 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding HlyIII PF03006.20 RUS69224.1 - 1.4e-36 126.3 19.1 3.7e-25 89.0 9.9 2.2 2 0 0 2 2 2 2 Haemolysin-III related FMO-like PF00743.19 RUS69225.1 - 2.3e-36 125.4 0.0 2.5e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Ebp2 PF05890.12 RUS69226.1 - 7.8e-53 179.7 42.7 1.3e-39 136.4 40.1 2.0 1 1 1 2 2 2 2 Eukaryotic rRNA processing protein EBP2 CCDC84 PF14968.6 RUS69226.1 - 0.0045 16.7 11.4 0.0063 16.2 11.4 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 WD40 PF00400.32 RUS69227.1 - 8.9e-28 96.0 14.2 6.5e-07 30.0 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS69227.1 - 7.1e-15 55.1 4.3 2.3e-05 24.6 0.4 4.3 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS69227.1 - 8.6e-08 32.3 0.2 0.00041 20.3 0.0 3.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RUS69227.1 - 1.4e-05 24.2 0.0 0.097 11.6 0.0 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 RUS69227.1 - 0.0093 14.6 0.2 0.022 13.4 0.0 1.6 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin Frtz PF11768.8 RUS69227.1 - 0.094 11.0 0.0 1.5 7.1 0.0 2.3 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TRAM_LAG1_CLN8 PF03798.16 RUS69228.1 - 4.8e-27 95.0 12.5 4.8e-27 95.0 12.5 1.7 2 0 0 2 2 2 1 TLC domain DUF5367 PF17329.2 RUS69228.1 - 0.25 11.5 4.2 0.13 12.4 1.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF5054 PF16477.5 RUS69229.1 - 1.6e-29 103.6 0.0 2.7e-14 53.6 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5054) FAD_binding_1 PF00667.20 RUS69230.1 - 2.7e-46 157.9 0.0 4.7e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RUS69230.1 - 2.8e-34 118.4 0.0 5.3e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RUS69230.1 - 7.4e-15 55.5 0.0 1.7e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 RUS69230.1 - 0.076 12.7 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain SNF PF00209.18 RUS69231.1 - 3e-157 524.5 23.3 3.4e-157 524.3 23.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Neur_chan_memb PF02932.16 RUS69232.1 - 4.2e-33 115.4 3.7 1.5e-27 97.2 3.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region rRNA_proc-arch PF13234.6 RUS69233.1 - 1.8e-84 283.9 0.1 1.8e-84 283.9 0.1 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 RUS69233.1 - 1.6e-58 197.0 0.3 3.7e-58 195.8 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 RUS69233.1 - 4e-18 65.8 0.0 9.7e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS69233.1 - 5.6e-06 26.7 0.0 2.7e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS69233.1 - 0.0002 21.4 0.0 0.00067 19.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3379 PF11859.8 RUS69233.1 - 0.1 11.9 0.7 0.29 10.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) ATPase_2 PF01637.18 RUS69233.1 - 0.11 12.4 1.4 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RUS69235.1 - 1.1e-27 97.3 0.0 1.5e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS69235.1 - 2.8e-05 23.7 0.0 0.00017 21.1 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS69235.1 - 0.052 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SHS2_Rpb7-N PF03876.17 RUS69235.1 - 0.054 13.9 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 ABC_membrane PF00664.23 RUS69236.1 - 1.6e-30 106.7 10.4 2e-30 106.4 10.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MTABC_N PF16185.5 RUS69237.1 - 3.4e-05 23.5 9.5 4.2e-05 23.2 9.5 1.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region RNase_H PF00075.24 RUS69238.1 - 5e-09 36.5 0.0 1.3e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 RUS69238.1 - 3e-08 33.5 0.0 9.2e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_3 PF13456.6 RUS69238.1 - 1.8e-06 27.8 0.1 3.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 RUS69238.1 - 5e-06 26.2 0.0 7.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RUS69238.1 - 0.00034 20.2 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Caveolin PF01146.17 RUS69239.1 - 5.3e-22 78.2 0.8 6.7e-22 77.9 0.8 1.0 1 0 0 1 1 1 1 Caveolin zf-C2H2 PF00096.26 RUS69241.1 - 0.0089 16.4 1.8 0.56 10.8 0.7 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69241.1 - 0.072 14.0 2.6 3 8.9 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS69241.1 - 0.14 11.9 5.8 1.9 8.3 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type MH1 PF03165.16 RUS69242.1 - 8.3e-41 138.4 0.1 1.2e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 MH1 domain DUF1955 PF09205.10 RUS69242.1 - 0.047 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Pox_A3L PF05288.11 RUS69243.1 - 4e-09 36.3 12.1 0.93 9.5 0.1 5.6 1 1 6 7 7 7 7 Poxvirus A3L Protein PPIP5K2_N PF18086.1 RUS69243.1 - 5.8e-05 23.2 8.9 15 5.8 0.2 5.0 1 1 4 5 5 5 4 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Shufflon_N PF04917.12 RUS69243.1 - 0.0016 17.9 0.0 12 5.2 0.0 3.1 1 1 2 3 3 3 3 Bacterial shufflon protein, N-terminal constant region Arv1 PF04161.13 RUS69243.1 - 0.0017 18.6 0.2 0.28 11.3 0.2 3.2 1 1 0 1 1 1 1 Arv1-like family DUF3876 PF12992.7 RUS69243.1 - 0.0071 16.4 0.9 18 5.5 0.1 3.4 1 1 4 5 5 5 1 Domain of unknown function, B. Theta Gene description (DUF3876) Dicty_CAD PF05720.12 RUS69243.1 - 0.013 15.4 14.6 31 4.6 0.1 5.9 1 1 8 9 9 9 0 Cell-cell adhesion domain Pet100 PF09803.9 RUS69243.1 - 0.11 13.1 24.6 1.2e+02 3.3 0.5 8.8 2 2 2 4 4 4 0 Pet100 DndE PF08870.11 RUS69243.1 - 0.19 12.0 0.9 30 4.9 0.0 3.4 1 1 4 5 5 5 0 DNA sulphur modification protein DndE Ehbp PF10622.9 RUS69243.1 - 0.3 11.1 23.5 32 4.6 0.4 6.7 1 1 4 5 5 5 0 Energy-converting hydrogenase B subunit P (EhbP) RNase_H_2 PF13482.6 RUS69244.1 - 0.014 15.4 0.6 0.11 12.5 0.3 1.9 1 1 1 2 2 2 0 RNase_H superfamily zinc_ribbon_10 PF10058.9 RUS69244.1 - 0.038 13.7 0.0 19 5.1 0.0 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein RNA_pol_N PF01194.17 RUS69244.1 - 0.093 13.0 0.0 22 5.5 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit MTHFR PF02219.17 RUS69245.1 - 5e-103 344.4 0.0 6.7e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cadherin PF00028.17 RUS69247.1 - 2.8e-106 348.2 49.3 1.9e-13 50.6 0.0 12.9 13 0 0 13 13 13 11 Cadherin domain Cadherin_3 PF16184.5 RUS69247.1 - 4.3e-11 42.8 25.5 0.032 14.2 0.3 9.3 10 0 0 10 10 10 5 Cadherin-like Cadherin_2 PF08266.12 RUS69247.1 - 0.00029 20.6 0.0 4.2 7.3 0.0 6.0 6 0 0 6 6 6 1 Cadherin-like GramPos_pilinD3 PF16570.5 RUS69247.1 - 0.07 13.9 1.7 0.25 12.1 0.4 2.7 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain MADF_DNA_bdg PF10545.9 RUS69248.1 - 2.3e-19 69.5 0.8 4.9e-19 68.4 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS69248.1 - 8.4e-07 28.7 1.3 1.6e-06 27.8 1.3 1.5 1 0 0 1 1 1 1 BESS motif Phage_terminase PF10668.9 RUS69248.1 - 0.0033 17.4 1.0 0.0084 16.1 1.0 1.6 1 0 0 1 1 1 1 Phage terminase small subunit DUF4050 PF13259.6 RUS69248.1 - 0.034 14.5 1.0 0.05 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Myb_DNA-bind_6 PF13921.6 RUS69248.1 - 0.038 14.2 0.2 0.12 12.7 0.2 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Neur_chan_memb PF02932.16 RUS69249.1 - 9.4e-32 111.0 0.0 1.3e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS69249.1 - 4.9e-13 49.0 0.0 7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain PIG-P PF08510.12 RUS69249.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PIG-P Prokineticin PF06607.11 RUS69250.1 - 0.95 9.8 10.0 2.5 8.5 10.0 1.8 1 1 0 1 1 1 0 Prokineticin RVT_1 PF00078.27 RUS69253.1 - 5.5e-22 78.4 0.0 1e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RUS69253.1 - 1.9e-15 56.7 0.0 5.8e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS69253.1 - 1.6e-05 25.1 0.0 4.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF1640 PF07798.11 RUS69254.1 - 7.1e-06 26.2 16.9 0.0025 17.9 2.2 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF1640) NID PF07292.13 RUS69254.1 - 0.081 13.6 6.4 0.77 10.4 1.6 3.0 1 1 1 2 2 2 0 Nmi/IFP 35 domain (NID) Cu_amine_oxidN1 PF07833.11 RUS69254.1 - 0.23 12.0 9.1 4.2 7.9 1.1 2.9 1 1 2 3 3 3 0 Copper amine oxidase N-terminal domain Coiled-coil_56 PF09813.9 RUS69254.1 - 0.24 11.5 10.3 7.9 6.6 2.3 2.9 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 56 FabA PF07977.13 RUS69254.1 - 0.36 10.5 10.8 4.4e+02 0.4 10.8 3.3 1 1 0 1 1 1 0 FabA-like domain Chalcone_N PF18232.1 RUS69254.1 - 0.37 11.2 11.6 1.2e+03 -0.1 11.0 3.9 1 1 0 1 1 1 0 Chalcone isomerase N-terminal domain DoxA PF07680.11 RUS69254.1 - 1.2 9.0 4.7 30 4.5 0.3 2.6 1 1 1 2 2 2 0 TQO small subunit DoxA DUF3456 PF11938.8 RUS69254.1 - 1.7 9.1 11.1 22 5.5 2.2 3.2 1 1 2 3 3 3 0 TLR4 regulator and MIR-interacting MSAP DUF272 PF03312.15 RUS69254.1 - 2.6 8.3 10.4 62 3.9 10.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF272) ShlB PF03865.13 RUS69254.1 - 5.8 6.3 7.4 13 5.1 7.1 1.7 1 1 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB 7tm_1 PF00001.21 RUS69255.1 - 9.9e-27 93.9 14.2 1.3e-26 93.6 14.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS69255.1 - 0.00029 20.3 12.5 0.00063 19.2 12.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS69255.1 - 0.0012 18.6 4.7 0.0012 18.6 4.7 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Proton_antipo_N PF00662.20 RUS69255.1 - 0.024 14.7 2.0 10 6.3 0.0 3.7 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus mono-CXXC PF15626.6 RUS69256.1 - 4.7 7.6 4.7 6.7 7.2 0.7 2.8 1 1 2 3 3 3 0 single CXXC unit PAGK PF15284.6 RUS69257.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor Na_Ca_ex PF01699.24 RUS69259.1 - 1.2e-25 90.2 16.7 2.3e-25 89.3 16.7 1.5 1 0 0 1 1 1 1 Sodium/calcium exchanger protein MFS_1 PF07690.16 RUS69261.1 - 1.1e-07 31.1 2.1 1.4e-07 30.8 2.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.18 RUS69262.1 - 1.5e-06 28.2 11.6 3.8e-06 26.9 11.6 1.7 1 0 0 1 1 1 1 MYND finger Ceramidase PF05875.12 RUS69264.1 - 4.9e-66 222.9 17.8 5.5e-66 222.7 17.8 1.0 1 0 0 1 1 1 1 Ceramidase 7TMR-DISM_7TM PF07695.11 RUS69264.1 - 0.27 11.1 20.6 3.9 7.3 20.6 2.1 1 1 0 1 1 1 0 7TM diverse intracellular signalling TssN PF17555.2 RUS69264.1 - 3.5 6.9 11.2 5.6 6.3 11.0 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN Copine PF07002.16 RUS69265.1 - 1.4e-69 233.9 0.0 2e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS69265.1 - 6.7e-28 97.0 0.0 8.3e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 RUS69265.1 - 0.0099 16.0 0.0 0.055 13.6 0.0 2.0 2 0 0 2 2 2 1 vWA found in TerF C terminus VCBS PF13517.6 RUS69265.1 - 0.039 14.5 0.3 0.19 12.3 0.1 2.4 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BTB PF00651.31 RUS69266.1 - 2.4e-27 95.3 2.3 3.2e-27 95.0 0.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 RUS69266.1 - 1.7e-26 91.5 22.5 1.5e-06 27.7 0.8 7.8 6 3 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RUS69266.1 - 2.2e-17 62.6 11.0 0.00026 21.1 0.1 7.0 4 2 2 6 6 6 4 Kelch motif BACK PF07707.15 RUS69266.1 - 3.4e-13 49.6 1.2 8.7e-13 48.3 1.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 RUS69266.1 - 2.8e-10 39.7 6.2 0.17 11.9 0.2 6.2 6 2 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 RUS69266.1 - 2e-09 37.5 9.1 0.3 11.4 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS69266.1 - 1.1e-06 28.6 16.6 0.31 11.1 0.0 6.8 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS69266.1 - 6.6e-06 26.0 6.2 0.44 10.6 0.0 5.5 6 0 0 6 6 6 2 Kelch motif FG-GAP PF01839.23 RUS69267.1 - 0.0051 16.9 4.5 0.13 12.5 0.1 3.4 3 0 0 3 3 3 1 FG-GAP repeat DUF4611 PF15387.6 RUS69267.1 - 0.062 13.5 5.6 1.1 9.5 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) VCBS PF13517.6 RUS69267.1 - 0.079 13.6 0.0 0.079 13.6 0.0 4.8 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Cwf_Cwc_15 PF04889.12 RUS69267.1 - 1.7 8.4 13.1 7 6.3 6.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Importin_rep_4 PF18808.1 RUS69267.1 - 7.6 6.9 6.8 0.75 10.1 2.0 1.8 2 0 0 2 2 2 0 Importin repeat 7tm_1 PF00001.21 RUS69269.1 - 6.8e-16 58.4 1.7 9.2e-16 58.0 1.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS69269.1 - 0.00026 20.4 3.3 0.00038 19.9 3.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0259 PF06790.11 RUS69269.1 - 0.008 16.0 0.2 0.0096 15.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) Git3 PF11710.8 RUS69269.1 - 0.014 15.2 1.9 0.02 14.7 1.9 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 7tm_4 PF13853.6 RUS69269.1 - 0.032 14.0 2.2 0.038 13.7 2.2 1.1 1 0 0 1 1 1 0 Olfactory receptor TMEM132D_C PF15706.5 RUS69269.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Saf_2TM PF18303.1 RUS69269.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain RNase_H PF00075.24 RUS69270.1 - 0.0024 18.0 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Glyco_hydro_18 PF00704.28 RUS69271.1 - 2e-46 159.2 0.0 2.4e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Keratin_matx PF04579.12 RUS69271.1 - 0.08 13.3 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Pribosyltran_N PF13793.6 RUS69272.1 - 6 6.9 7.3 18 5.3 0.2 3.9 2 2 1 3 3 3 0 N-terminal domain of ribose phosphate pyrophosphokinase zf-C4 PF00105.18 RUS69273.1 - 2.6e-27 95.1 13.5 2.6e-27 95.1 13.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS69273.1 - 2.9e-09 36.8 0.0 2.9e-09 36.8 0.0 2.5 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Spt20 PF12090.8 RUS69273.1 - 0.78 9.3 32.2 0.47 10.0 23.2 2.5 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.9 RUS69273.1 - 2.3 6.4 26.2 0.35 9.1 20.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 RUS69273.1 - 2.6 7.0 9.3 0.098 11.7 3.0 1.7 2 0 0 2 2 2 0 Solute carrier family 12 TFIIA PF03153.13 RUS69273.1 - 5 7.0 40.9 0.28 11.1 23.7 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Herpes_BLLF1 PF05109.13 RUS69274.1 - 6.2e-08 31.1 11.7 0.00016 19.9 0.6 3.0 1 1 2 3 3 3 3 Herpes virus major outer envelope glycoprotein (BLLF1) Cep57_CLD PF14073.6 RUS69275.1 - 1.1e-42 146.1 19.5 1.1e-42 146.1 19.5 2.8 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 RUS69275.1 - 8.4e-11 42.2 0.3 8.4e-11 42.2 0.3 4.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Ada3 PF10198.9 RUS69275.1 - 0.036 14.2 0.1 0.036 14.2 0.1 3.8 4 1 0 4 4 4 0 Histone acetyltransferases subunit 3 Corona_S2 PF01601.16 RUS69275.1 - 0.04 12.4 0.3 0.063 11.8 0.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.11 RUS69275.1 - 2.3 6.1 6.6 1.8 6.4 0.7 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-6_N PF09177.11 RUS69275.1 - 6.8 7.3 11.8 0.28 11.8 0.6 3.5 2 2 1 3 3 3 0 Syntaxin 6, N-terminal tRNA_bind PF01588.20 RUS69276.1 - 1.1e-25 89.6 0.0 1.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1b PF00579.25 RUS69276.1 - 7.5e-20 71.4 0.0 9.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fibrinogen_C PF00147.18 RUS69277.1 - 1.4e-08 34.8 1.2 1.6e-08 34.6 1.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DIM PF08194.12 RUS69278.1 - 0.035 14.3 0.4 0.07 13.3 0.4 1.5 1 0 0 1 1 1 0 DIM protein FeS_assembly_P PF01883.19 RUS69279.1 - 1.5e-07 31.5 0.1 2.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein LRS4 PF10422.9 RUS69279.1 - 0.019 14.5 0.2 0.032 13.8 0.0 1.4 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Nif11 PF07862.11 RUS69279.1 - 0.13 12.6 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Nif11 domain MPLKIP PF15502.6 RUS69281.1 - 2.1e-08 34.3 0.3 8.3e-08 32.3 0.2 2.1 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein MSG PF02349.15 RUS69282.1 - 1.7e-05 24.9 19.2 0.12 12.6 1.8 4.1 2 2 2 4 4 4 4 Major surface glycoprotein Nuc_recep-AF1 PF11825.8 RUS69282.1 - 0.0022 18.0 7.8 3.5 7.7 0.4 3.6 1 1 3 4 4 4 3 Nuclear/hormone receptor activator site AF-1 NCOA_u2 PF16665.5 RUS69282.1 - 0.044 14.1 2.1 24 5.2 2.1 3.8 1 1 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein DUF4744 PF15918.5 RUS69282.1 - 0.42 11.5 15.4 0.83 10.5 5.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) Paramecium_SA PF01508.16 RUS69282.1 - 1.3 9.5 25.9 18 5.8 4.5 4.5 2 2 0 2 2 2 0 Paramecium surface antigen domain Sulfotransfer_1 PF00685.27 RUS69284.1 - 0.085 12.3 0.0 0.27 10.7 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase domain Nkap_C PF06047.11 RUS69286.1 - 4.8e-46 155.1 1.5 4.8e-46 155.1 1.5 2.7 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain PA26 PF04636.13 RUS69286.1 - 6 5.7 10.0 13 4.6 10.0 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) p450 PF00067.22 RUS69292.1 - 5.8e-101 338.5 0.0 6.7e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4756 PF15948.5 RUS69292.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) Amidohydro_1 PF01979.20 RUS69293.1 - 2.4e-21 76.4 0.0 4.1e-21 75.7 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RUS69293.1 - 0.00049 19.7 0.0 0.0025 17.3 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family 2-Hacid_dh_C PF02826.19 RUS69294.1 - 2.7e-57 193.0 0.0 3.6e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS69294.1 - 2e-30 105.2 0.0 2.4e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RUS69294.1 - 0.044 14.0 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase COMM_domain PF07258.14 RUS69295.1 - 1.3e-11 44.4 0.6 2.3e-11 43.6 0.6 1.4 1 0 0 1 1 1 1 COMM domain gag-asp_proteas PF13975.6 RUS69296.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 RUS69296.1 - 1.7 8.5 7.6 0.18 11.7 2.3 2.2 3 0 0 3 3 3 0 Zinc knuckle YyzF PF14116.6 RUS69296.1 - 4.9 7.3 5.8 10 6.2 0.3 2.8 1 1 1 2 2 2 0 YyzF-like protein zf-CCHC PF00098.23 RUS69296.1 - 9.3 6.5 12.1 0.13 12.4 3.0 2.5 2 0 0 2 2 2 0 Zinc knuckle Fibrinogen_C PF00147.18 RUS69297.1 - 9.2e-58 195.6 7.9 1.3e-57 195.1 7.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS69297.1 - 5.1e-05 23.3 10.4 0.014 15.5 1.0 2.6 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC53 PF10152.9 RUS69297.1 - 0.00034 21.1 8.8 0.021 15.2 2.4 2.7 1 1 1 2 2 2 2 Subunit CCDC53 of WASH complex DUF2730 PF10805.8 RUS69297.1 - 0.0011 19.1 10.4 0.35 11.0 0.6 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2730) Phasin PF05597.11 RUS69297.1 - 0.0011 19.0 4.7 0.067 13.2 0.1 3.9 2 1 2 4 4 4 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 RUS69297.1 - 0.0012 18.7 1.6 0.0014 18.5 0.2 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 RUS69297.1 - 0.0015 18.7 13.4 0.026 14.8 2.5 3.3 2 2 1 3 3 3 2 ABC transporter C-terminal domain NPV_P10 PF05531.12 RUS69297.1 - 0.0026 18.2 6.8 29 5.2 6.8 3.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MAD PF05557.13 RUS69297.1 - 0.0035 15.8 6.9 0.0052 15.2 6.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Tropomyosin_1 PF12718.7 RUS69297.1 - 0.0046 17.1 13.0 0.062 13.5 5.0 2.3 1 1 1 2 2 2 2 Tropomyosin like BLOC1_2 PF10046.9 RUS69297.1 - 0.024 14.9 15.2 0.1 12.9 1.7 3.5 2 1 3 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 RUS69297.1 - 0.037 11.6 5.9 0.051 11.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XhlA PF10779.9 RUS69297.1 - 0.049 13.8 20.7 0.33 11.2 2.2 4.1 2 1 2 4 4 4 0 Haemolysin XhlA HAUS-augmin3 PF14932.6 RUS69297.1 - 0.092 12.3 6.0 0.17 11.5 5.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 RUS69297.1 - 0.1 12.9 5.6 0.3 11.4 0.3 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 RUS69297.1 - 0.16 9.9 8.7 0.22 9.5 8.7 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 RUS69297.1 - 0.23 11.5 8.3 0.55 10.3 8.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RUS69297.1 - 0.25 11.4 12.4 4.7 7.3 4.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.13 RUS69297.1 - 0.78 9.9 9.0 16 5.7 0.6 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.21 RUS69297.1 - 0.9 10.1 10.2 0.82 10.2 2.2 2.7 2 1 1 3 3 3 0 Spectrin repeat EMP24_GP25L PF01105.24 RUS69297.1 - 0.92 9.4 10.3 0.4 10.6 0.6 3.5 2 1 2 4 4 4 0 emp24/gp25L/p24 family/GOLD HSBP1 PF06825.12 RUS69297.1 - 0.94 9.4 14.2 1.8 8.5 2.0 4.1 2 1 2 4 4 4 0 Heat shock factor binding protein 1 DUF489 PF04356.12 RUS69297.1 - 1.1 9.3 4.8 8 6.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Occludin_ELL PF07303.13 RUS69297.1 - 1.4 9.7 5.9 11 6.7 1.2 3.1 1 1 1 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.11 RUS69297.1 - 1.5 8.6 12.7 2.9 7.7 3.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 FapA PF03961.13 RUS69297.1 - 1.6 7.3 10.6 1.5 7.3 9.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A MCU PF04678.13 RUS69297.1 - 1.7 8.8 5.0 5.1 7.2 0.3 2.5 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Prefoldin_2 PF01920.20 RUS69297.1 - 2.1 8.4 15.8 1.7 8.7 6.5 3.0 2 1 1 3 3 2 0 Prefoldin subunit FlaC_arch PF05377.11 RUS69297.1 - 3.3 8.2 20.6 4.4 7.8 1.2 4.8 2 1 4 6 6 5 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RUS69297.1 - 3.4 8.0 6.3 3.4 8.0 0.3 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_Prp PF04327.12 RUS69297.1 - 4.6 7.5 6.7 23 5.3 0.3 3.4 1 1 2 3 3 3 0 Cysteine protease Prp DUF16 PF01519.16 RUS69297.1 - 7.1 7.2 12.0 3.7 8.1 3.7 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 zf-RVT PF13966.6 RUS69299.1 - 3.6e-05 24.4 0.2 9.1e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PDDEXK_6 PF04720.12 RUS69299.1 - 0.12 12.3 1.0 2.5 8.0 1.1 2.1 2 0 0 2 2 2 0 PDDEXK-like family of unknown function CENP-B_dimeris PF09026.10 RUS69299.1 - 0.14 12.6 24.6 0.29 11.6 24.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RUS69299.1 - 0.29 10.8 9.0 0.51 10.0 9.0 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 RUS69299.1 - 0.41 8.7 22.5 0.52 8.3 22.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RUS69299.1 - 0.64 9.1 27.0 0.99 8.5 27.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 RUS69299.1 - 0.64 10.0 12.7 1.5 8.9 12.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Afi1 PF07792.12 RUS69299.1 - 1.1 9.7 9.9 1.7 9.2 9.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BUD22 PF09073.10 RUS69299.1 - 2.1 7.6 11.5 2.8 7.2 11.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS69299.1 - 3.7 5.6 16.9 4.8 5.3 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 RUS69299.1 - 4.3 7.8 22.0 14 6.2 22.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFB6 PF17110.5 RUS69299.1 - 5.5 6.7 9.7 9.8 5.9 9.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Utp14 PF04615.13 RUS69299.1 - 7 5.1 12.0 9.6 4.6 12.0 1.1 1 0 0 1 1 1 0 Utp14 protein ATAD4 PF15321.6 RUS69300.1 - 2.8e-05 25.4 4.0 2.8e-05 25.4 4.0 2.1 2 0 0 2 2 2 1 ATPase family AAA domain containing 4 fn3 PF00041.21 RUS69301.1 - 0.0008 19.7 0.1 0.0019 18.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TMEM154 PF15102.6 RUS69301.1 - 0.057 13.3 2.8 0.19 11.6 0.0 2.4 1 1 0 2 2 2 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RUS69301.1 - 0.085 12.6 2.6 0.13 12.0 2.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AsmA PF05170.14 RUS69301.1 - 0.12 11.1 7.9 1.5 7.6 6.2 2.1 2 0 0 2 2 2 0 AsmA family ECSCR PF15820.5 RUS69301.1 - 0.19 11.6 0.3 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator MLANA PF14991.6 RUS69301.1 - 0.28 11.5 1.7 0.48 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein melan-A Arteri_Gl PF00951.18 RUS69301.1 - 0.33 10.7 1.4 0.56 10.0 1.4 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein SID-1_RNA_chan PF13965.6 RUS69301.1 - 3 6.1 4.4 6.5 5.0 4.4 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2681 PF10883.8 RUS69301.1 - 3.2 8.2 8.9 3 8.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) Ndc1_Nup PF09531.10 RUS69301.1 - 5 5.7 6.0 6.6 5.3 6.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5305 PF17231.2 RUS69302.1 - 0.084 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Profilin PF00235.19 RUS69303.1 - 8.1e-09 35.8 0.0 1e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Profilin REPA_OB_2 PF16900.5 RUS69304.1 - 2.1e-13 50.0 3.2 3.2e-08 33.4 0.2 2.5 2 0 0 2 2 2 2 Replication protein A OB domain Acyl-CoA_dh_1 PF00441.24 RUS69305.1 - 6.5e-43 146.5 0.9 6.5e-43 146.5 0.9 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS69305.1 - 6.9e-35 120.1 0.0 1.3e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RUS69305.1 - 5.9e-28 96.9 0.0 1.1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RUS69305.1 - 1.5e-10 41.5 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_C1 PF00112.23 RUS69306.1 - 4.3e-23 82.6 0.3 5.8e-23 82.1 0.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Zw10 PF06248.13 RUS69307.1 - 3.1e-91 306.6 8.7 4e-91 306.2 8.7 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 FadA PF09403.10 RUS69307.1 - 0.11 13.0 4.4 0.32 11.5 4.4 1.8 1 0 0 1 1 1 0 Adhesion protein FadA Exonuc_VII_L PF02601.15 RUS69307.1 - 0.15 11.6 4.1 0.3 10.6 4.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit GIT1_C PF12205.8 RUS69307.1 - 0.49 10.5 3.5 0.78 9.9 0.1 2.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1069 PF06370.11 RUS69309.1 - 1.2 8.7 5.5 8.5 5.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) CRPV_capsid PF08762.10 RUS69309.1 - 1.3 8.6 9.9 1 9.0 4.0 2.1 1 1 1 2 2 2 0 CRPV capsid protein like Adap_comp_sub PF00928.21 RUS69310.1 - 3.9e-80 269.0 0.0 5.1e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS69310.1 - 2.8e-07 30.5 0.5 4.7e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 RUS69310.1 - 0.04 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Glyco_transf_8 PF01501.20 RUS69311.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 Sigma_reg_N PF13800.6 RUS69311.1 - 0.059 13.7 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Euplotes_phero PF05842.11 RUS69311.1 - 3.5 8.2 4.6 0.98 10.0 0.6 1.9 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein Casc1_N PF15927.5 RUS69312.1 - 0.0048 16.6 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Cancer susceptibility candidate 1 N-terminus TetR_C_4 PF08359.11 RUS69312.1 - 0.012 15.7 0.3 0.024 14.8 0.3 1.4 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region MRP-S24 PF14955.6 RUS69312.1 - 0.078 13.0 0.2 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 Tnp_P_element_C PF12596.8 RUS69312.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 87kDa Transposase MMR_HSR1 PF01926.23 RUS69313.1 - 1.1e-13 51.3 0.1 6.1e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS69313.1 - 1.6e-07 31.0 0.2 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS69313.1 - 1.8e-07 31.2 0.2 0.0042 17.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TLP-20 PF06088.11 RUS69313.1 - 0.015 15.2 2.7 0.015 15.2 2.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.13 RUS69313.1 - 0.021 14.7 6.6 0.034 14.0 6.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region AIG1 PF04548.16 RUS69313.1 - 0.023 14.0 1.7 0.056 12.8 0.1 2.1 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 RUS69313.1 - 0.055 13.0 0.4 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CDC45 PF02724.14 RUS69313.1 - 0.11 10.8 12.7 0.14 10.4 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Gtr1_RagA PF04670.12 RUS69313.1 - 0.16 11.3 0.4 0.53 9.6 0.1 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Nop14 PF04147.12 RUS69313.1 - 0.76 7.9 19.4 1.1 7.4 19.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS69313.1 - 1 8.7 22.2 1.6 7.9 22.2 1.2 1 0 0 1 1 1 0 BUD22 7tm_1 PF00001.21 RUS69314.1 - 1.7e-21 76.8 9.6 2e-21 76.5 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS69314.1 - 0.071 13.1 0.3 0.071 13.1 0.3 2.7 3 0 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_4 PF13853.6 RUS69314.1 - 0.079 12.7 12.8 0.64 9.7 12.8 2.1 1 1 0 1 1 1 0 Olfactory receptor DUF4577 PF15145.6 RUS69314.1 - 0.23 11.5 1.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) ig PF00047.25 RUS69316.1 - 0.037 14.2 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ten1_2 PF15490.6 RUS69316.1 - 0.061 13.0 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit Ig_3 PF13927.6 RUS69316.1 - 0.087 13.4 0.2 0.26 11.9 0.2 1.9 1 1 0 1 1 1 0 Immunoglobulin domain CENP-Q PF13094.6 RUS69316.1 - 0.091 13.0 2.3 0.72 10.0 0.5 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.12 RUS69316.1 - 0.11 13.1 1.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 SlyX Matrilin_ccoil PF10393.9 RUS69316.1 - 0.26 11.2 3.7 1.9 8.4 0.2 2.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Spt20 PF12090.8 RUS69318.1 - 4.5 6.8 15.1 8.7 5.9 15.1 1.4 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 RUS69319.1 - 9.9e-31 106.9 42.0 2.7e-22 79.2 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily U83 PF17465.2 RUS69319.1 - 0.021 14.9 0.6 0.047 13.8 0.2 1.7 2 0 0 2 2 2 0 Chemokine-like protein, HHV-6 U83 gene product C2 PF00168.30 RUS69320.1 - 1.6e-16 60.4 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain Homeodomain PF00046.29 RUS69321.1 - 3.9e-13 49.0 1.5 7.1e-13 48.2 1.5 1.4 1 0 0 1 1 1 1 Homeodomain NTP_transf_2 PF01909.23 RUS69324.1 - 6.4e-09 36.0 1.2 7 7.0 0.0 7.3 1 1 6 7 7 7 1 Nucleotidyltransferase domain NOP19 PF10863.8 RUS69324.1 - 1.4e-05 24.9 5.7 0.15 11.8 0.6 3.2 1 1 2 3 3 3 3 Nucleolar protein 19 FLYWCH_u PF16662.5 RUS69324.1 - 0.00056 19.9 0.7 43 4.3 0.0 5.2 1 1 6 7 7 7 0 FLYWCH-type zinc finger-containing protein 1 Thx PF17070.5 RUS69324.1 - 0.029 14.5 32.7 68 3.8 0.1 9.0 9 0 0 9 9 9 0 30S ribosomal protein Thx Pox_polyA_pol PF03296.13 RUS69324.1 - 0.23 11.4 4.3 1.2e+02 2.6 0.0 4.4 1 1 4 5 5 5 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Rho_N PF07498.12 RUS69324.1 - 0.26 11.3 15.4 98 3.0 0.1 7.4 6 2 2 8 8 8 0 Rho termination factor, N-terminal domain Phage_B PF02304.15 RUS69324.1 - 0.32 11.4 9.1 9.3 6.7 5.8 2.5 1 1 1 2 2 2 0 Scaffold protein B DegQ PF08181.11 RUS69324.1 - 0.46 10.6 17.0 2.4 8.3 0.8 4.3 1 1 3 4 4 4 0 DegQ (SacQ) family UB2H PF14814.6 RUS69324.1 - 0.56 10.3 18.6 27 4.9 0.3 4.5 1 1 7 8 8 8 0 Bifunctional transglycosylase second domain DNA_pol_B_palm PF14792.6 RUS69324.1 - 0.76 10.0 34.9 29 4.9 0.1 8.3 1 1 8 9 9 9 0 DNA polymerase beta palm ArfA PF03889.13 RUS69324.1 - 2.1 7.9 37.9 47 3.6 0.2 8.8 9 0 0 9 9 9 0 Alternative ribosome-rescue factor A SelR PF01641.18 RUS69325.1 - 5.2e-32 110.5 0.5 4.5e-31 107.5 0.2 2.0 2 0 0 2 2 2 1 SelR domain Glyco_transf_64 PF09258.10 RUS69328.1 - 3.6e-72 242.6 0.1 5.1e-72 242.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RUS69328.1 - 3.9e-26 92.0 0.0 7.3e-25 87.8 0.0 2.4 2 1 0 2 2 2 1 Exostosin family APG6_N PF17675.1 RUS69328.1 - 8.8e-06 26.3 0.3 1.6e-05 25.4 0.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 RUS69328.1 - 4e-05 23.7 1.2 9.1e-05 22.5 1.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 RUS69328.1 - 0.0083 15.3 2.8 0.016 14.3 2.8 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 RUS69328.1 - 0.014 15.6 3.1 0.027 14.7 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 RUS69328.1 - 0.018 15.3 2.7 0.037 14.2 2.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 RUS69328.1 - 0.03 14.6 1.4 0.06 13.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 RUS69328.1 - 0.072 12.4 3.4 0.12 11.6 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fungal_TACC PF12709.7 RUS69328.1 - 0.079 13.4 3.4 0.083 13.3 1.7 1.8 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 RUS69328.1 - 0.093 13.2 5.8 0.23 11.9 5.8 1.7 1 0 0 1 1 1 0 Cell division protein ZapB GAS PF13851.6 RUS69328.1 - 0.13 11.6 3.2 0.24 10.7 3.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 RUS69328.1 - 0.15 12.1 0.9 0.31 11.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FPP PF05911.11 RUS69328.1 - 0.2 9.8 1.5 0.29 9.3 1.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 RUS69328.1 - 0.26 10.1 2.8 0.41 9.5 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 RUS69328.1 - 0.5 9.9 5.8 0.86 9.2 5.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BRE1 PF08647.11 RUS69328.1 - 0.97 9.6 5.3 2.2 8.4 5.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 RUS69328.1 - 1.1 10.0 3.8 3 8.5 1.8 2.4 2 0 0 2 2 2 0 SlyX DMPK_coil PF08826.10 RUS69328.1 - 2.1 8.5 8.2 0.35 11.0 3.0 2.1 1 1 1 2 2 2 0 DMPK coiled coil domain like THOC7 PF05615.13 RUS69328.1 - 2.2 8.6 5.6 4.6 7.5 4.9 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 BTB_2 PF02214.22 RUS69330.1 - 3.2e-15 56.3 0.0 1e-09 38.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 RUS69330.1 - 0.026 14.6 0.0 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain DUF2465 PF10239.9 RUS69331.1 - 1.6e-121 405.5 0.3 1.9e-121 405.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Presenilin PF01080.17 RUS69332.1 - 2.2e-159 530.5 0.2 2.2e-159 530.5 0.2 1.4 2 0 0 2 2 2 1 Presenilin ABC_tran PF00005.27 RUS69333.1 - 1.6e-22 80.5 0.0 2.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 RUS69333.1 - 2.8e-07 31.2 0.8 4.2e-07 30.7 0.1 1.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RUS69333.1 - 6.4e-07 29.0 0.0 6e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RUS69333.1 - 1.2e-06 28.6 0.0 0.005 16.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS69333.1 - 0.00084 19.0 0.1 0.002 17.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS69333.1 - 0.00095 19.1 0.0 0.0031 17.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 RUS69333.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RUS69333.1 - 0.0018 18.5 0.0 0.0063 16.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RUS69333.1 - 0.022 14.5 0.0 0.063 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 RUS69333.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RUS69333.1 - 0.051 12.9 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 RUS69333.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 RUS69333.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 RUS69333.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RUS69333.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RUS69333.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 RUS69333.1 - 0.21 10.2 0.2 1.7 7.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 RUS69334.1 - 0.00032 20.8 29.4 0.00032 20.8 29.4 2.3 1 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit HLH PF00010.26 RUS69335.1 - 0.019 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TOBE_2 PF08402.10 RUS69335.1 - 0.078 13.1 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 TOBE domain Importin_rep_3 PF18806.1 RUS69336.1 - 2.3 8.3 9.8 5.1 7.2 0.2 3.0 1 1 2 3 3 3 0 Importin 13 repeat DUF760 PF05542.11 RUS69336.1 - 3 8.3 6.7 27 5.2 6.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF760) NPCC PF08058.11 RUS69336.1 - 7.9 6.5 11.2 46 4.1 11.2 2.0 1 1 0 1 1 1 0 Nuclear pore complex component Cu_bind_CorA PF18252.1 RUS69337.1 - 0.22 11.1 2.0 1 9.0 1.0 2.6 2 1 1 3 3 3 0 Copper(I)-binding protein CorA PDZ PF00595.24 RUS69338.1 - 6.9e-07 29.5 0.4 6.9e-07 29.5 0.4 2.0 2 0 0 2 2 2 1 PDZ domain C2 PF00168.30 RUS69338.1 - 0.00046 20.4 0.0 0.00093 19.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 RUS69338.1 - 0.00047 20.0 0.4 0.0011 18.7 0.4 1.6 1 0 0 1 1 1 1 PDZ domain Lin-8 PF03353.15 RUS69339.1 - 0.013 15.1 2.1 0.013 15.1 2.1 3.0 3 1 0 3 3 3 0 Ras-mediated vulval-induction antagonist TMEM247 PF15444.6 RUS69339.1 - 0.014 15.4 3.8 0.08 13.0 0.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 247 SSF PF00474.17 RUS69340.1 - 1.6e-19 70.1 20.9 3.2e-19 69.1 20.9 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family Pro_isomerase PF00160.21 RUS69341.1 - 3.4e-45 154.2 0.2 4.1e-45 153.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DAGAT PF03982.13 RUS69343.1 - 2.6e-118 394.2 0.0 3.3e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PGM1_C PF18105.1 RUS69344.1 - 0.1 12.2 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 PGM1 C-terminal domain TFIIS_C PF01096.18 RUS69346.1 - 2.4e-16 59.3 6.8 2.4e-16 59.3 6.8 2.9 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 RUS69346.1 - 0.0057 16.6 9.5 0.0067 16.4 1.2 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DZR PF12773.7 RUS69346.1 - 0.0088 16.1 8.7 0.059 13.4 0.5 2.5 2 1 0 2 2 2 1 Double zinc ribbon zf-MYND PF01753.18 RUS69346.1 - 0.0091 16.1 0.9 1.6 8.9 0.1 2.8 2 2 0 2 2 2 1 MYND finger Baculo_LEF5_C PF11792.8 RUS69346.1 - 0.052 13.2 0.6 0.052 13.2 0.6 2.8 3 1 1 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain NOB1_Zn_bind PF08772.11 RUS69346.1 - 0.11 12.6 4.7 6 7.1 0.3 2.7 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like XAF1_C PF18608.1 RUS69346.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.4 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain TF_Zn_Ribbon PF08271.12 RUS69346.1 - 0.94 9.0 10.0 3.9 7.1 0.0 3.5 3 1 1 4 4 4 0 TFIIB zinc-binding Rpr2 PF04032.16 RUS69346.1 - 1.2 9.5 5.6 11 6.4 5.6 2.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 RUS69346.1 - 1.2 8.6 0.0 1.2 8.6 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 RUS69346.1 - 2.1 8.3 13.6 0.57 10.1 1.6 3.4 3 2 0 3 3 2 0 RNA polymerases M/15 Kd subunit DUF2387 PF09526.10 RUS69346.1 - 2.7 8.2 9.3 0.39 10.9 0.9 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF3268 PF11672.8 RUS69346.1 - 3.1 8.1 6.5 16 5.9 2.3 2.7 3 0 0 3 3 3 0 zinc-finger-containing domain RecR PF02132.15 RUS69346.1 - 3.2 7.4 6.1 12 5.6 0.7 3.1 3 1 1 4 4 3 0 RecR protein zf_UBZ PF18439.1 RUS69346.1 - 5.3 6.7 0.0 5.3 6.7 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Ribosomal_S27e PF01667.17 RUS69346.1 - 5.7 6.7 7.5 18 5.1 0.2 2.9 2 1 0 2 2 2 0 Ribosomal protein S27 PhnA_Zn_Ribbon PF08274.12 RUS69346.1 - 7.8 6.6 7.1 6 6.9 0.0 2.8 3 1 0 3 3 2 0 PhnA Zinc-Ribbon zf-TFIIB PF13453.6 RUS69346.1 - 9.2 5.7 9.8 1.9 7.9 1.3 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Peptidase_S28 PF05577.12 RUS69347.1 - 8.9e-72 242.2 0.0 1.1e-71 241.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 RUS69347.1 - 0.00029 20.6 0.1 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS69347.1 - 0.00033 20.0 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RUS69347.1 - 0.00039 20.0 0.1 0.00068 19.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS69347.1 - 0.0023 18.5 0.1 0.0062 17.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 RUS69347.1 - 0.0099 14.6 0.2 0.018 13.7 0.2 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_2 PF02230.16 RUS69347.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2920 PF11144.8 RUS69347.1 - 0.12 11.5 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) LSM PF01423.22 RUS69349.1 - 4e-19 68.1 0.6 4.9e-19 67.8 0.6 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 RUS69349.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 RUS69349.1 - 0.025 14.7 0.2 0.033 14.3 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 RUS69349.1 - 0.043 13.7 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) TUDOR PF00567.24 RUS69352.1 - 1.6e-112 370.4 11.9 1e-27 96.6 0.1 5.9 5 0 0 5 5 5 5 Tudor domain Agenet PF05641.12 RUS69352.1 - 1.2e-11 44.9 6.3 0.77 10.3 0.0 6.0 5 0 0 5 5 5 4 Agenet domain zf-B_box PF00643.24 RUS69352.1 - 5.5e-08 32.8 2.4 5.5e-08 32.8 2.4 4.0 4 0 0 4 4 4 2 B-box zinc finger SMN PF06003.12 RUS69352.1 - 3.5e-07 29.8 11.8 0.048 12.9 0.1 5.4 5 1 1 6 6 6 2 Survival motor neuron protein (SMN) DUF4537 PF15057.6 RUS69352.1 - 1.4e-05 25.1 3.4 1.3 9.0 0.0 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF4537) zf-RING_5 PF14634.6 RUS69352.1 - 0.00019 21.3 5.5 0.00019 21.3 5.5 3.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF1325 PF07039.11 RUS69352.1 - 0.00021 21.4 1.3 1.5 8.9 0.0 4.0 4 0 0 4 4 4 2 SGF29 tudor-like domain zf-RING_UBOX PF13445.6 RUS69352.1 - 0.00054 19.9 6.9 0.0038 17.2 7.0 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RUS69352.1 - 6.9 7.1 26.2 0.46 10.9 5.0 3.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 RUS69352.1 - 9.4 6.5 21.3 0.015 15.4 2.6 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-H3C2 PF16721.5 RUS69353.1 - 0.047 14.0 0.0 0.065 13.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding CN_hydrolase PF00795.22 RUS69354.1 - 3.6e-35 121.6 0.0 4.3e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fumerase PF05681.14 RUS69355.1 - 3.2e-89 298.9 0.3 4.6e-89 298.4 0.3 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 RUS69355.1 - 4.4e-78 261.3 0.1 6.5e-78 260.8 0.1 1.3 1 0 0 1 1 1 1 Fumarase C-terminus DUF3945 PF13101.6 RUS69355.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) FKBP_C PF00254.28 RUS69356.1 - 5.1e-08 33.1 0.1 6.9e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2187 PF09953.9 RUS69356.1 - 0.051 13.6 0.1 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) Radical_SAM PF04055.21 RUS69357.1 - 3.1e-28 99.2 0.0 1.4e-27 97.1 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 RUS69357.1 - 1.2e-15 57.3 0.2 3e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 CDKN3 PF05706.12 RUS69357.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) peroxidase PF00141.23 RUS69358.1 - 3.6e-82 275.5 0.0 2.8e-47 161.3 0.0 2.4 2 1 0 2 2 2 2 Peroxidase HAD PF12710.7 RUS69359.1 - 8.5e-17 62.2 0.0 1.2e-16 61.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS69359.1 - 3.7e-09 37.2 0.0 7.6e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RUS69359.1 - 9.1e-06 25.9 0.2 0.0001 22.4 0.2 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RUS69359.1 - 0.00046 20.0 0.1 1.3 8.7 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 RUS69359.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 RUS69359.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.8 1 1 0 1 1 1 0 Putative Phosphatase Pkinase PF00069.25 RUS69361.1 - 5.6e-35 121.0 0.0 8.9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69361.1 - 2.8e-16 59.6 0.0 4.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS69361.1 - 0.00046 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS69361.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RUS69361.1 - 0.0048 15.9 0.8 0.02 13.9 0.5 2.2 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 RUS69361.1 - 0.085 12.2 0.9 0.14 11.5 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS69361.1 - 0.14 12.0 0.8 0.32 10.9 0.8 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ERCC4 PF02732.15 RUS69362.1 - 1.1e-22 81.0 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain WD40 PF00400.32 RUS69363.1 - 2.3e-14 53.6 19.0 0.00019 22.1 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.11 RUS69363.1 - 9.8e-05 22.3 0.3 0.035 14.0 0.2 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RUS69363.1 - 0.00017 20.4 2.7 0.086 11.5 0.3 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RUS69363.1 - 0.00062 20.0 0.1 0.015 15.6 0.5 2.7 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_32 PF13679.6 RUS69364.1 - 2.8e-26 92.4 1.0 1.7e-25 89.9 1.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS69364.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS69364.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CDC73_N PF16050.5 RUS69364.1 - 0.058 12.7 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal PCMT PF01135.19 RUS69364.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Neur_chan_LBD PF02931.23 RUS69365.1 - 1e-30 106.8 1.9 2.3e-27 95.9 0.1 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS69365.1 - 3e-17 63.5 16.8 8.1e-17 62.1 7.8 2.9 1 1 2 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 RUS69365.1 - 0.0069 14.6 41.5 0.0097 14.1 41.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.11 RUS69365.1 - 0.012 14.2 22.7 0.024 13.2 22.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1218 PF06749.12 RUS69365.1 - 0.04 14.4 0.6 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CDC45 PF02724.14 RUS69365.1 - 0.073 11.4 21.3 0.11 10.8 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS69365.1 - 0.12 10.8 21.1 0.17 10.3 21.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS69365.1 - 0.25 9.5 31.6 0.43 8.7 31.6 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS69365.1 - 1.5 8.2 33.2 2 7.7 33.2 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS69365.1 - 3.9 6.8 25.6 5.6 6.3 25.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CNDH2_C PF16858.5 RUS69365.1 - 7.8 6.3 12.5 12 5.6 12.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 RUS69365.1 - 9.9 5.4 9.8 15 4.9 9.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1397 PF07165.11 RUS69368.1 - 0.023 14.1 5.8 0.025 14.0 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1397) Frag1 PF10277.9 RUS69370.1 - 8.8e-36 123.5 14.2 1.1e-35 123.2 14.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Pox_A14 PF05767.12 RUS69370.1 - 0.15 12.2 3.1 0.75 10.0 0.0 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DREV PF05219.12 RUS69373.1 - 5.8e-23 81.3 0.0 9.5e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RNase_H PF00075.24 RUS69373.1 - 2.1e-09 37.7 0.1 1.7e-07 31.5 0.1 2.7 2 1 0 2 2 2 1 RNase H Lectin_C PF00059.21 RUS69375.1 - 3.4e-07 30.9 0.6 7e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 RUS69375.1 - 0.00071 19.5 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 PAN domain Ig_3 PF13927.6 RUS69376.1 - 2.8e-31 107.9 0.0 1.8e-12 47.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS69376.1 - 5.3e-26 90.5 0.0 1.1e-08 35.0 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS69376.1 - 4e-23 81.5 0.1 2.3e-09 37.5 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS69376.1 - 1.1e-15 57.6 0.0 3.6e-06 27.1 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS69376.1 - 1e-11 45.0 1.1 0.033 14.4 0.1 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 RUS69376.1 - 3.3e-06 27.0 0.0 2.2 8.4 0.0 3.6 3 1 0 3 3 3 3 C17orf99 Ig domain Ig_5 PF16681.5 RUS69376.1 - 8.7e-06 26.1 0.0 0.18 12.2 0.0 3.1 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS69376.1 - 0.00044 20.4 0.1 0.33 11.2 0.0 3.2 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS69376.1 - 0.00071 19.1 0.1 2.4 7.8 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Receptor_2B4 PF11465.8 RUS69376.1 - 0.0022 18.2 0.0 5.3 7.3 0.0 3.0 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 C2-set PF05790.15 RUS69376.1 - 0.0054 16.9 0.0 10 6.4 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin C2-set domain Sclerostin PF05463.11 RUS69377.1 - 3.4e-32 111.8 13.9 3.4e-32 111.8 13.9 1.6 1 1 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 RUS69377.1 - 6.4e-11 42.3 3.6 1.1e-10 41.5 3.6 1.4 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 RUS69377.1 - 1.4e-05 25.3 2.7 2.1e-05 24.7 2.7 1.3 1 0 0 1 1 1 1 Cystine-knot domain LRIF1 PF15741.5 RUS69377.1 - 0.45 9.0 13.9 0.53 8.7 13.9 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 YAF2_RYBP PF17219.3 RUS69378.1 - 0.0011 18.5 0.1 4.4e+02 0.6 0.0 7.1 9 0 0 9 9 9 0 Yaf2/RYBP C-terminal binding motif GrlR PF16518.5 RUS69378.1 - 0.053 13.5 1.0 13 5.7 0.2 3.2 1 1 1 2 2 2 0 T3SS negative regulator,GrlR DUF4233 PF14017.6 RUS69378.1 - 0.37 11.2 6.9 5.3 7.4 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) CAP_GLY PF01302.25 RUS69379.1 - 1.7e-16 60.0 0.3 3.9e-16 58.8 0.3 1.6 1 1 0 1 1 1 1 CAP-Gly domain Tudor_2 PF18104.1 RUS69379.1 - 0.045 13.4 0.6 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Serpin PF00079.20 RUS69380.1 - 1.1e-34 120.3 0.0 1.3e-34 120.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 RUS69381.1 - 8.8e-19 68.0 0.0 9.6e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) zf-Nse PF11789.8 RUS69383.1 - 1.2e-17 63.5 0.1 2.1e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 RUS69383.1 - 0.00047 19.9 0.3 0.001 18.8 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.15 RUS69383.1 - 0.0051 17.0 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.6 RUS69383.1 - 0.0073 16.3 0.5 0.017 15.1 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS69383.1 - 0.0083 16.0 0.1 0.022 14.6 0.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) THOC7 PF05615.13 RUS69383.1 - 0.014 15.6 0.9 0.022 15.0 0.9 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 zf-RING_2 PF13639.6 RUS69383.1 - 0.036 14.4 0.5 0.076 13.4 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 RUS69383.1 - 0.048 13.7 0.2 0.087 12.9 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cnn_1N PF07989.11 RUS69383.1 - 0.063 13.4 2.6 0.91 9.7 0.2 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-rbx1 PF12678.7 RUS69383.1 - 0.073 13.4 0.1 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Uso1_p115_C PF04871.13 RUS69383.1 - 2 8.8 6.4 1.1 9.6 1.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LUD_dom PF02589.15 RUS69384.1 - 0.0015 18.3 7.0 30 4.2 0.0 8.3 2 1 12 14 14 14 1 LUD domain EIIA-man PF03610.16 RUS69384.1 - 0.094 13.0 0.2 48 4.2 0.0 3.8 1 1 5 6 6 6 0 PTS system fructose IIA component RAP PF08373.10 RUS69384.1 - 5.1 7.3 18.6 85 3.4 0.2 6.6 3 1 4 7 7 7 0 RAP domain CUB PF00431.20 RUS69386.1 - 6.3e-33 113.4 0.1 7e-33 113.3 0.1 1.0 1 0 0 1 1 1 1 CUB domain PTB PF08416.13 RUS69389.1 - 1.5e-35 122.2 0.0 2.6e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 RUS69389.1 - 6.4e-11 42.2 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain TFIIA PF03153.13 RUS69389.1 - 0.065 13.2 9.0 0.094 12.7 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 RUS69389.1 - 1.6 6.9 9.0 2.3 6.4 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.14 RUS69389.1 - 9 5.6 12.6 19 4.5 12.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UQ_con PF00179.26 RUS69390.1 - 7.2e-50 168.3 0.0 8.1e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sulfotransfer_1 PF00685.27 RUS69391.1 - 2.3e-21 76.5 0.0 2.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS69391.1 - 3.7e-16 60.2 0.1 6.2e-12 46.4 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS69391.1 - 0.0047 16.9 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family DAGK_acc PF00609.19 RUS69393.1 - 8.8e-53 178.9 0.0 1.6e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain RA PF00788.23 RUS69393.1 - 8.1e-28 96.9 0.3 8.3e-18 64.8 0.4 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DAGK_cat PF00781.24 RUS69393.1 - 7.2e-24 83.8 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RUS69393.1 - 1.9e-11 43.7 28.8 3.1e-06 27.0 7.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TUG-UBL1 PF11470.8 RUS69393.1 - 0.0008 19.6 0.1 5.8 7.2 0.0 3.5 3 0 0 3 3 3 2 TUG ubiquitin-like domain C1_2 PF03107.16 RUS69393.1 - 2.1 8.7 16.6 0.12 12.7 6.3 2.6 2 1 0 2 2 2 0 C1 domain Myb_DNA-bind_5 PF13873.6 RUS69394.1 - 1.3e-25 89.3 6.4 1.5e-12 47.4 0.6 2.2 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RUS69394.1 - 2.8e-08 34.0 5.6 0.00064 20.0 0.5 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 RUS69394.1 - 1.4e-06 28.4 2.2 0.0078 16.4 0.2 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 RUS69394.1 - 3e-06 27.5 2.4 0.033 14.5 0.2 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 RUS69394.1 - 5e-05 23.5 7.3 0.034 14.4 0.7 2.9 2 2 0 2 2 2 2 Myb-like DNA-binding domain PRC2_HTH_1 PF18118.1 RUS69394.1 - 0.00011 22.9 3.4 0.0027 18.5 1.7 2.3 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain DUF3106 PF11304.8 RUS69394.1 - 0.00012 22.5 0.9 0.052 14.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3106) DUP PF00674.18 RUS69394.1 - 0.0018 18.4 0.3 0.3 11.2 0.1 2.4 2 0 0 2 2 2 1 DUP family DUF2280 PF10045.9 RUS69394.1 - 0.0071 16.6 0.2 0.6 10.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2280) Spectrin PF00435.21 RUS69394.1 - 0.016 15.6 1.3 4.7 7.8 0.2 2.5 2 0 0 2 2 2 0 Spectrin repeat Ykof PF07615.11 RUS69394.1 - 0.021 15.3 0.0 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 YKOF-related Family DUF2390 PF09523.10 RUS69394.1 - 0.065 13.6 0.6 0.25 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) DNA_pol_lambd_f PF10391.9 RUS69394.1 - 0.21 11.4 1.3 16 5.4 0.1 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Amidinotransf PF02274.17 RUS69395.1 - 0.017 14.3 1.6 0.024 13.7 1.6 1.2 1 0 0 1 1 1 0 Amidinotransferase Pex14_N PF04695.13 RUS69395.1 - 0.44 11.2 9.0 1.2 9.8 9.0 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 RUS69395.1 - 1.1 9.4 15.7 0.32 11.1 4.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 C4bp_oligo PF18453.1 RUS69395.1 - 1.7 8.9 8.3 1 9.6 2.4 2.3 1 1 1 2 2 2 0 Oligomerization domain of C4b-binding protein alpha SH2 PF00017.24 RUS69396.1 - 6.5e-15 55.0 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Med11 PF10280.9 RUS69397.1 - 1.9e-18 67.3 2.9 1.9e-18 67.3 2.9 2.1 1 1 1 2 2 2 1 Mediator complex protein ALMT PF11744.8 RUS69397.1 - 9.6 4.9 11.1 11 4.7 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sulfate_transp PF00916.20 RUS69398.1 - 8.5e-57 192.6 37.8 1.7e-32 112.6 10.2 2.2 1 1 1 2 2 2 2 Sulfate permease family adh_short_C2 PF13561.6 RUS69399.1 - 4.3e-51 173.7 0.1 4.9e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS69399.1 - 4.7e-42 143.7 0.1 5.5e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS69399.1 - 3.7e-08 33.5 0.1 6.5e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RUS69399.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 RUS69399.1 - 0.00017 21.1 0.1 0.00021 20.8 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS69399.1 - 0.0002 20.9 0.2 0.00035 20.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 RUS69399.1 - 0.0017 18.9 0.1 0.14 12.7 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 RUS69399.1 - 0.0039 17.1 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 RUS69399.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 RUS69399.1 - 0.015 14.5 0.2 0.02 14.0 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein S-layer PF07752.11 RUS69399.1 - 0.046 12.8 0.2 0.071 12.2 0.2 1.2 1 0 0 1 1 1 0 S-layer protein RmlD_sub_bind PF04321.17 RUS69399.1 - 0.057 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 RUS69399.1 - 0.11 12.8 0.1 0.24 11.7 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TatD_DNase PF01026.21 RUS69400.1 - 5.9e-67 225.7 0.0 6.6e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Queuosine_synth PF02547.15 RUS69401.1 - 4.9e-56 190.2 0.1 6.5e-56 189.8 0.1 1.1 1 0 0 1 1 1 1 Queuosine biosynthesis protein Hydrolase_3 PF08282.12 RUS69401.1 - 6.4e-19 68.7 0.3 9.9e-19 68.1 0.3 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS69401.1 - 0.00031 21.1 0.2 0.001 19.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS69401.1 - 0.0028 18.1 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RUS69401.1 - 0.0057 16.2 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Peptidase_M99 PF17033.5 RUS69401.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Neur_chan_LBD PF02931.23 RUS69403.1 - 9e-50 169.1 0.4 1.6e-49 168.3 0.4 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS69403.1 - 3.5e-35 122.2 6.3 1.6e-31 110.2 6.3 2.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MgtE PF01769.16 RUS69403.1 - 3.6 8.0 9.4 1.1 9.6 2.1 2.5 2 0 0 2 2 2 0 Divalent cation transporter BRI3BP PF14965.6 RUS69403.1 - 5.9 6.4 8.6 2.7 7.5 2.5 2.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 O-FucT PF10250.9 RUS69404.1 - 1.6e-77 261.4 0.3 1.9e-77 261.2 0.3 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 RUS69404.1 - 0.035 13.3 0.8 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 11 ENTH PF01417.20 RUS69405.1 - 7.9e-15 55.0 0.0 1.4e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 RUS69405.1 - 0.00016 20.8 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 RUS69405.1 - 0.003 17.4 0.1 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 VHS domain CENP-B_dimeris PF09026.10 RUS69405.1 - 3.9 7.9 12.6 11 6.5 12.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GP3_package PF16677.5 RUS69406.1 - 0.013 15.6 1.4 0.02 15.0 1.2 1.4 1 1 0 1 1 1 0 DNA-packaging protein gp3 DUF1359 PF07097.11 RUS69406.1 - 0.69 10.2 8.6 0.32 11.3 3.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1359) TMF_TATA_bd PF12325.8 RUS69406.1 - 1.9 8.7 17.2 1.5 9.1 6.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.12 RUS69406.1 - 1.9 8.5 8.0 3.7 7.6 1.4 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Cauli_AT PF03233.13 RUS69406.1 - 4.4 7.2 9.5 1.7 8.6 2.1 2.3 1 1 1 2 2 2 0 Aphid transmission protein TMF_DNA_bd PF12329.8 RUS69406.1 - 9.1 6.4 18.2 0.25 11.4 3.0 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 RUS69406.1 - 9.8 6.8 13.3 17 6.1 6.1 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Gal-bind_lectin PF00337.22 RUS69408.1 - 3.2e-11 42.9 0.0 5.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin ATG_C PF09333.11 RUS69409.1 - 0.0095 16.3 3.1 0.11 12.9 2.0 2.3 1 1 1 2 2 2 2 Autophagy-related protein C terminal domain TrbC PF04956.13 RUS69409.1 - 0.091 13.0 4.4 12 6.2 0.1 3.4 2 1 2 4 4 4 0 TrbC/VIRB2 family SMBP PF16785.5 RUS69409.1 - 0.12 12.6 7.0 0.55 10.5 1.7 2.2 1 1 1 2 2 2 0 Small metal-binding protein MT0933_antitox PF14013.6 RUS69409.1 - 0.82 10.0 37.4 1.7 9.0 14.6 3.8 2 1 1 3 3 3 0 MT0933-like antitoxin protein DUF5610 PF18433.1 RUS69409.1 - 1 9.8 8.0 7.9 7.0 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5610) LRR_8 PF13855.6 RUS69410.1 - 3e-11 42.9 4.8 6.6e-07 29.0 1.4 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS69410.1 - 1.2e-07 31.9 6.5 0.0012 19.2 0.9 3.2 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Ank_5 PF13857.6 RUS69410.1 - 0.00011 22.4 0.0 0.018 15.3 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS69410.1 - 0.0049 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS69410.1 - 0.0052 17.2 0.0 7.4 7.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat LRR_1 PF00560.33 RUS69410.1 - 0.0068 16.8 0.5 19 6.3 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 RUS69410.1 - 0.068 13.3 0.6 3.5 7.9 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 RUS69411.1 - 0.00027 21.2 0.1 0.00042 20.6 0.1 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS69411.1 - 0.0099 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS69411.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 RUS69412.1 - 5.9e-05 22.8 2.1 0.039 13.7 0.2 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS69412.1 - 0.00013 22.3 0.3 0.41 11.1 0.1 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS69412.1 - 0.025 14.6 0.6 4.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 RUS69412.1 - 0.061 13.9 0.4 19 6.3 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat Roc PF08477.13 RUS69413.1 - 2.4e-20 73.0 0.0 2.4e-18 66.5 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS69413.1 - 1.3e-09 37.9 0.0 5.9e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 Ras family Arf PF00025.21 RUS69413.1 - 0.00019 20.9 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS69413.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 RUS69413.1 - 0.002 18.3 0.0 0.0058 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RUS69413.1 - 0.0093 16.0 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 RUS69413.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 RUS69413.1 - 0.18 12.0 0.1 0.26 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain QVR PF17064.5 RUS69415.1 - 0.047 13.9 0.4 0.16 12.2 0.4 1.9 1 0 0 1 1 1 0 Sleepless protein VPS9 PF02204.18 RUS69415.1 - 0.13 12.4 0.0 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Vac_Fusion PF02346.16 RUS69415.1 - 0.51 10.0 7.5 0.073 12.7 0.6 3.0 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Cpn60_TCP1 PF00118.24 RUS69416.1 - 3.6e-162 540.4 6.3 4.1e-162 540.2 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF643 PF04867.12 RUS69416.1 - 0.025 15.2 0.2 0.18 12.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF643) PMP22_Claudin PF00822.20 RUS69418.1 - 7e-10 39.0 11.6 8.8e-10 38.7 11.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS69418.1 - 2.4e-05 24.2 13.4 0.0002 21.2 13.4 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 RUS69418.1 - 3e-05 23.6 6.2 0.00012 21.7 0.9 2.1 2 0 0 2 2 2 2 Clc-like Nore1-SARAH PF16517.5 RUS69419.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Mem_trans PF03547.18 RUS69419.1 - 5.4 5.3 7.8 1.6 7.0 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein RGS-like PF09128.11 RUS69422.1 - 2.2 7.9 9.9 3.6 7.3 9.9 1.4 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain DUF2981 PF11200.8 RUS69422.1 - 3.5 7.3 4.8 3.6 7.2 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MULE PF10551.9 RUS69423.1 - 3.1e-21 75.6 1.2 6.3e-21 74.6 0.2 2.2 2 0 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 RUS69423.1 - 4.5e-19 68.6 1.4 1.9e-18 66.5 0.2 2.4 2 1 0 2 2 2 1 Family of unknown function (DUF5575) FAR1 PF03101.15 RUS69423.1 - 8.7e-07 29.6 1.4 2.6e-06 28.0 1.4 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain PHD PF00628.29 RUS69423.1 - 0.0045 16.8 8.9 0.011 15.6 8.9 1.7 1 0 0 1 1 1 1 PHD-finger DDE_Tnp_ISL3 PF01610.17 RUS69423.1 - 0.037 13.8 6.5 0.012 15.3 2.5 2.2 2 1 0 2 2 2 0 Transposase Claudin_3 PF06653.11 RUS69424.1 - 0.018 15.0 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF1072 PF06380.11 RUS69424.1 - 0.067 13.1 1.8 0.2 11.5 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1072) Clc-like PF07062.12 RUS69424.1 - 0.098 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Clc-like CD36 PF01130.21 RUS69425.1 - 5.3e-127 424.2 1.0 7.1e-127 423.8 1.0 1.0 1 0 0 1 1 1 1 CD36 family PorA PF11271.8 RUS69425.1 - 0.0068 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Porin PorA Syndecan PF01034.20 RUS69425.1 - 3.4 7.6 5.2 0.45 10.5 0.3 2.0 2 0 0 2 2 2 0 Syndecan domain Dpy-30 PF05186.13 RUS69426.1 - 8.9e-20 70.1 0.2 1.2e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 RUS69426.1 - 0.00099 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF3599 PF12206.8 RUS69427.1 - 0.0014 18.9 0.6 6.5 7.1 0.0 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF3599) DUF1856 PF08983.10 RUS69427.1 - 0.0024 18.1 2.1 2.1 8.6 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1856) VPS38 PF17649.1 RUS69427.1 - 0.02 13.8 3.2 3.7 6.3 0.2 2.8 1 1 2 3 3 3 0 Vacuolar protein sorting 38 PNP_UDP_1 PF01048.20 RUS69428.1 - 1.4e-47 161.9 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily FAR1 PF03101.15 RUS69428.1 - 1.1e-05 26.0 0.2 2.4e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain RVT_1 PF00078.27 RUS69429.1 - 1.2e-14 54.3 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-TRAF PF02176.18 RUS69430.1 - 4e-20 72.3 26.4 4.4e-12 46.5 7.1 4.4 1 1 3 4 4 4 4 TRAF-type zinc finger Sina PF03145.16 RUS69430.1 - 1.6e-11 44.6 18.1 1.7e-05 24.8 2.5 3.3 1 1 2 3 3 3 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 RUS69430.1 - 2.9e-07 30.9 22.2 0.00014 22.2 5.2 3.2 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 RUS69430.1 - 0.00039 20.2 1.6 0.00039 20.2 1.6 3.5 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS69430.1 - 0.00072 19.5 0.8 0.00072 19.5 0.8 3.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS69430.1 - 0.00092 19.5 1.5 0.00092 19.5 1.5 3.4 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RUS69430.1 - 0.0012 18.6 1.5 0.0012 18.6 1.5 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS69430.1 - 0.0013 18.8 1.8 0.0013 18.8 1.8 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS69430.1 - 0.0055 16.7 2.8 0.0055 16.7 2.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf_C2H2_13 PF18508.1 RUS69430.1 - 0.012 15.2 1.3 2.6 7.7 0.1 2.8 2 0 0 2 2 2 0 Zinc finger domain Prok-RING_4 PF14447.6 RUS69430.1 - 0.015 15.2 4.0 0.015 15.2 4.0 3.3 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS69430.1 - 0.041 13.7 0.5 0.041 13.7 0.5 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf_UBZ PF18439.1 RUS69430.1 - 0.18 11.4 6.5 0.27 10.9 0.2 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 RUS69430.1 - 0.36 10.9 5.3 0.24 11.5 1.2 2.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf_C2HC_14 PF18574.1 RUS69430.1 - 2.1 8.2 10.1 13 5.7 0.2 3.9 3 0 0 3 3 3 0 C2HC Zing finger domain DNA_pol_alpha_N PF12254.8 RUS69431.1 - 1.3e-19 70.0 12.4 2.7e-19 69.0 12.4 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Cna_B PF05738.13 RUS69431.1 - 0.025 15.1 0.4 0.048 14.2 0.4 1.4 1 0 0 1 1 1 0 Cna protein B-type domain COX16 PF14138.6 RUS69431.1 - 1.5 9.4 7.5 3.9 8.0 7.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 GMP_PDE_delta PF05351.11 RUS69432.1 - 1.4e-74 249.3 1.4 1.9e-74 249.0 1.4 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit zf-C3HC4_3 PF13920.6 RUS69434.1 - 7.8e-13 48.1 11.3 7.8e-13 48.1 11.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 RUS69434.1 - 6.5e-06 26.1 2.8 0.035 14.0 0.2 2.6 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding FYVE PF01363.21 RUS69434.1 - 1.8e-05 24.8 7.8 1.8e-05 24.8 7.8 3.2 2 1 0 2 2 2 1 FYVE zinc finger Prok-RING_4 PF14447.6 RUS69434.1 - 0.00074 19.3 10.6 0.00074 19.3 10.6 3.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RUS69434.1 - 0.004 16.9 12.8 0.004 16.9 12.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4518 PF15008.6 RUS69434.1 - 0.02 14.1 0.1 5.4 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) zf-C3HC4_4 PF15227.6 RUS69434.1 - 0.025 14.7 4.6 0.025 14.7 4.6 3.8 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING HeH PF12949.7 RUS69434.1 - 0.11 12.3 0.3 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 HeH/LEM domain Nucleo_P87 PF07267.11 RUS69434.1 - 0.16 10.8 9.7 0.013 14.4 2.5 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-C3HC4 PF00097.25 RUS69434.1 - 1.3 9.0 32.0 0.097 12.6 12.9 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.13 RUS69435.1 - 2.1e-29 102.9 0.0 7.4e-20 71.7 0.0 2.0 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS69435.1 - 0.0006 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 RUS69435.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 RUS69435.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 RUS69435.1 - 0.041 13.4 0.2 0.062 12.8 0.2 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Adaptin_N PF01602.20 RUS69436.1 - 4.7e-46 157.4 0.3 5.4e-46 157.2 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Kinetochor_Ybp2 PF08568.10 RUS69436.1 - 0.0018 16.9 0.0 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HEAT_2 PF13646.6 RUS69436.1 - 0.011 16.1 0.3 0.47 10.9 0.1 2.5 1 1 1 2 2 2 0 HEAT repeats Cnd1 PF12717.7 RUS69436.1 - 0.014 15.4 0.5 0.037 14.1 0.2 1.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 RUS69436.1 - 0.027 13.0 0.2 0.032 12.8 0.2 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 RUS69436.1 - 0.091 13.1 1.0 4 7.9 0.0 3.2 3 1 0 3 3 3 0 HEAT repeat RICTOR_M PF14666.6 RUS69436.1 - 0.12 12.2 0.4 6.4 6.6 0.1 2.5 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Rad21_Rec8 PF04824.16 RUS69438.1 - 0.15 11.4 1.6 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein Fibrinogen_C PF00147.18 RUS69439.1 - 2.3e-54 184.5 4.6 3.1e-54 184.1 4.6 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ATG27 PF09451.10 RUS69440.1 - 3.4e-15 56.6 0.0 2e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 RUS69440.1 - 2.4e-14 53.1 0.8 3.2e-13 49.4 0.8 2.1 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ECSCR PF15820.5 RUS69440.1 - 0.00092 19.0 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator PARM PF17061.5 RUS69440.1 - 0.0076 16.4 1.2 0.012 15.8 1.2 1.4 1 1 0 1 1 1 1 PARM DUF5599 PF18141.1 RUS69441.1 - 0.056 13.7 0.0 1.6 9.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5599) EF-hand_7 PF13499.6 RUS69442.1 - 7.3e-13 48.8 4.7 2.8e-10 40.5 2.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS69442.1 - 8.9e-08 31.2 11.5 0.0015 17.9 0.3 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RUS69442.1 - 2.3e-07 30.2 8.4 0.0018 18.0 0.6 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RUS69442.1 - 0.0026 17.6 10.4 0.015 15.1 1.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS69442.1 - 0.014 15.7 1.4 0.026 14.9 0.4 1.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS69442.1 - 0.069 13.1 2.4 0.11 12.4 0.6 2.1 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Glycos_trans_3N PF02885.17 RUS69442.1 - 0.2 11.5 1.4 1.1 9.2 0.1 2.5 3 1 1 4 4 4 0 Glycosyl transferase family, helical bundle domain RNA_pol_Rpb4 PF03874.16 RUS69443.1 - 6.6e-24 84.6 0.0 7.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Kri1_C PF12936.7 RUS69444.1 - 5.3e-20 71.4 1.7 5.3e-20 71.4 1.7 6.2 8 0 0 8 8 8 1 KRI1-like family C-terminal Kri1 PF05178.12 RUS69444.1 - 6.8e-13 49.1 18.5 6.8e-13 49.1 18.5 7.4 4 3 2 6 6 6 1 KRI1-like family HMG_box PF00505.19 RUS69445.1 - 1.7e-13 50.8 0.3 4.8e-13 49.3 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Amidoligase_2 PF12224.8 RUS69446.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme tRNA-synt_1 PF00133.22 RUS69449.1 - 3e-230 765.6 0.0 4.7e-230 764.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RUS69449.1 - 1.4e-24 86.7 0.0 2.7e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RUS69449.1 - 6.2e-15 54.8 0.2 0.00013 20.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Reprolysin_5 PF13688.6 RUS69450.1 - 8.3e-14 52.2 0.3 1.4e-13 51.4 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 ADAM_CR_2 PF17771.1 RUS69450.1 - 1.4e-10 41.5 5.4 2.4e-10 40.8 4.2 2.0 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RUS69450.1 - 3.4e-09 37.3 0.1 7.4e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS69450.1 - 9.9e-07 28.9 0.2 1.8e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 RUS69450.1 - 2e-05 24.6 0.7 4e-05 23.6 0.7 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS69450.1 - 0.0011 18.6 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SPRY PF00622.28 RUS69451.1 - 1.5e-18 67.0 0.0 2.9e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 RUS69451.1 - 0.00015 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 SOCS box LRR_9 PF14580.6 RUS69452.1 - 2.7e-76 255.0 4.8 3.7e-76 254.5 4.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RUS69452.1 - 1e-06 28.9 12.7 0.00012 22.4 4.6 4.1 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS69452.1 - 2e-05 24.3 7.7 3.3e-05 23.6 5.7 2.4 1 1 2 3 3 3 3 Leucine rich repeat BUD22 PF09073.10 RUS69452.1 - 0.00071 19.0 18.1 0.00093 18.7 18.1 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 RUS69452.1 - 2 8.3 21.6 2.6 8.0 21.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RUS69452.1 - 2.4 6.1 26.9 3.8 5.5 26.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Mak16 PF04874.14 RUS69452.1 - 5.5 7.7 24.6 0.4 11.3 19.1 2.0 2 0 0 2 2 2 0 Mak16 protein C-terminal region FYDLN_acid PF09538.10 RUS69452.1 - 6.3 7.5 25.7 5.6 7.7 22.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CobT PF06213.12 RUS69452.1 - 6.3 6.1 23.4 10 5.4 23.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HlyIII PF03006.20 RUS69453.1 - 6.1e-29 101.3 29.9 4.3e-28 98.6 29.1 2.0 2 0 0 2 2 2 1 Haemolysin-III related DUF2070 PF09843.9 RUS69453.1 - 0.13 10.6 11.0 0.17 10.2 11.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HlyIII PF03006.20 RUS69454.1 - 7.5e-30 104.3 22.8 1e-29 103.9 22.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related NDUF_B12 PF08122.12 RUS69454.1 - 0.022 14.8 0.1 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF962 PF06127.11 RUS69454.1 - 0.03 14.4 0.8 0.52 10.4 0.7 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF962) zf-C4 PF00105.18 RUS69455.1 - 2 9.0 7.4 4.8 7.7 7.4 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) MFS_1 PF07690.16 RUS69456.1 - 1.4e-46 159.1 29.2 1.9e-46 158.6 29.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 RUS69456.1 - 0.22 9.9 9.0 0.22 9.9 1.2 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector DUF2700 PF10912.8 RUS69456.1 - 0.73 9.9 8.9 0.71 9.9 0.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2700) Fringe PF02434.16 RUS69457.1 - 1.4e-06 28.0 0.2 5.9e-06 25.9 0.2 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS69457.1 - 1.8e-05 24.7 0.0 0.00011 22.2 0.0 2.0 1 1 1 2 2 2 1 Galactosyltransferase NADH-u_ox-rdase PF10785.9 RUS69457.1 - 0.096 13.4 0.2 0.33 11.7 0.2 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cpn60_TCP1 PF00118.24 RUS69458.1 - 4.7e-06 25.5 0.9 8.3e-06 24.7 0.9 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 RUS69459.1 - 1e-11 44.2 0.2 2e-11 43.3 0.1 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Sacchrp_dh_C PF16653.5 RUS69460.1 - 2.8e-57 194.9 0.0 4.2e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 RUS69460.1 - 1.6e-15 57.5 0.0 2.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 RUS69460.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Na_sulph_symp PF00939.19 RUS69461.1 - 3.4e-60 204.4 6.6 3e-37 128.8 3.0 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS69461.1 - 9e-31 107.2 10.2 2e-10 40.4 10.3 3.1 2 1 1 3 3 3 3 Citrate transporter Ion_trans_2 PF07885.16 RUS69463.1 - 7.7e-38 128.3 17.7 2.4e-19 69.0 0.7 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS69463.1 - 7.1e-07 28.7 11.1 0.00011 21.5 0.1 2.4 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 RUS69463.1 - 0.23 11.3 1.6 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel CPSF100_C PF13299.6 RUS69464.1 - 0.00066 19.9 3.0 0.00085 19.5 3.0 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 RUS69464.1 - 0.00095 18.2 4.6 0.0013 17.8 4.6 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) CDC45 PF02724.14 RUS69464.1 - 0.0098 14.2 22.7 0.011 14.1 22.7 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS69464.1 - 0.012 15.1 32.9 0.015 14.8 32.9 1.1 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 RUS69464.1 - 0.058 12.2 8.5 0.072 11.9 8.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 RUS69464.1 - 0.068 12.0 11.7 0.081 11.7 11.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 RUS69464.1 - 0.073 12.5 9.9 0.09 12.2 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 RUS69464.1 - 0.082 13.3 5.4 0.11 12.9 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 RUS69464.1 - 0.095 11.1 40.3 0.12 10.8 40.3 1.0 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 RUS69464.1 - 0.11 11.2 7.4 0.14 10.9 7.4 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 RUS69464.1 - 0.14 10.5 0.5 0.14 10.5 0.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.17 RUS69464.1 - 0.15 12.2 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 DDHD domain MCM_bind PF09739.9 RUS69464.1 - 0.2 10.1 4.5 0.24 9.8 4.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PPL5 PF18168.1 RUS69464.1 - 0.3 10.4 6.7 0.38 10.0 6.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Nop14 PF04147.12 RUS69464.1 - 0.31 9.2 38.9 0.38 8.9 38.9 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.6 RUS69464.1 - 0.32 10.7 2.2 0.36 10.6 2.2 1.1 1 0 0 1 1 1 0 AAA domain Raftlin PF15250.6 RUS69464.1 - 0.43 9.3 5.5 0.5 9.1 5.5 1.1 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.6 RUS69464.1 - 0.65 9.6 4.7 0.77 9.3 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.15 RUS69464.1 - 1.1 8.0 11.3 1.2 7.8 11.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 RUS69464.1 - 1.4 7.9 3.3 1.8 7.6 3.3 1.1 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 RUS69464.1 - 1.8 8.3 18.9 2.2 8.0 18.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Smg8_Smg9 PF10220.9 RUS69464.1 - 1.9 6.7 5.6 2.2 6.5 5.6 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Hid1 PF12722.7 RUS69464.1 - 2.8 5.9 6.6 3.5 5.7 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_phi PF04931.13 RUS69464.1 - 5.1 5.1 45.4 7 4.6 45.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi RAB3GAP2_C PF14656.6 RUS69464.1 - 5.5 5.1 5.4 6.9 4.8 5.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Zip PF02535.22 RUS69464.1 - 5.6 6.1 13.2 17 4.5 13.2 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 RUS69464.1 - 6 6.7 27.1 9.6 6.1 27.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2151 PF10221.9 RUS69464.1 - 6.5 5.2 9.8 8 4.9 9.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Serinc PF03348.15 RUS69464.1 - 7.4 5.4 5.2 8.6 5.2 5.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) L_protein_N PF15518.6 RUS69465.1 - 0.085 12.7 0.1 0.4 10.5 0.0 2.0 2 1 0 2 2 2 0 L protein N-terminus Ets PF00178.22 RUS69466.1 - 4.4e-31 107.2 0.7 5.2e-31 107.0 0.7 1.1 1 0 0 1 1 1 1 Ets-domain An_peroxidase PF03098.15 RUS69467.1 - 2e-50 171.9 0.3 1.8e-47 162.2 0.1 2.1 1 1 1 2 2 2 2 Animal haem peroxidase Neuralized PF07177.12 RUS69468.1 - 4.5e-38 130.6 0.0 8.3e-38 129.7 0.0 1.4 1 1 0 1 1 1 1 Neuralized SOCS_box PF07525.16 RUS69468.1 - 0.1 13.0 3.9 0.25 11.8 3.9 1.7 1 0 0 1 1 1 0 SOCS box G-alpha PF00503.20 RUS69469.1 - 1.1e-105 353.7 0.2 1.3e-105 353.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS69469.1 - 6.8e-15 55.0 1.0 9.3e-12 44.7 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS69469.1 - 4.4e-05 22.9 1.7 0.0025 17.2 0.0 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RUS69469.1 - 0.00026 21.2 0.2 0.32 11.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RUS69469.1 - 0.017 14.6 0.0 0.53 9.8 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.21 RUS69469.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 RUS69469.1 - 0.1 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 RUS69469.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain B PF02216.16 RUS69469.1 - 0.18 11.8 1.1 17 5.5 0.1 3.3 3 0 0 3 3 3 0 B domain Tmemb_170 PF10190.9 RUS69470.1 - 1.3e-42 144.5 9.4 1.5e-42 144.3 9.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 TMEM70 PF06979.12 RUS69471.1 - 1.5e-36 125.7 5.6 2.3e-36 125.1 5.6 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF563 PF04577.14 RUS69472.1 - 9.4e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) fn3 PF00041.21 RUS69472.1 - 0.014 15.8 0.1 0.04 14.3 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain RB_B PF01857.20 RUS69473.1 - 3e-48 163.2 0.0 6.1e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 RUS69474.1 - 5.2e-30 104.7 0.7 7.2e-30 104.3 0.7 1.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain Sperm_Ag_HE2 PF05324.13 RUS69474.1 - 0.02 15.3 0.5 2.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Sperm antigen HE2 PNK3P PF08645.11 RUS69475.1 - 3.4e-59 199.1 0.7 5.6e-59 198.5 0.7 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase FHA_2 PF17913.1 RUS69475.1 - 1.4e-30 105.4 0.0 3.7e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain AAA_33 PF13671.6 RUS69475.1 - 0.00012 22.2 0.0 0.00072 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain FHA PF00498.26 RUS69475.1 - 0.031 14.6 0.5 0.096 13.1 0.1 2.1 2 0 0 2 2 2 0 FHA domain Hydrolase_6 PF13344.6 RUS69475.1 - 0.05 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIIF_alpha PF05793.12 RUS69475.1 - 0.05 12.2 16.6 0.075 11.6 16.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_M24 PF00557.24 RUS69476.1 - 1.1e-41 142.8 0.0 1.6e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RUS69476.1 - 2.3e-26 91.9 0.0 5.4e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 RUS69476.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) THAP PF05485.12 RUS69478.1 - 4.6e-12 46.7 19.7 1.7e-08 35.3 9.8 2.8 2 1 1 3 3 3 2 THAP domain Tap-RNA_bind PF09162.10 RUS69478.1 - 0.021 14.6 0.3 0.063 13.1 0.3 1.8 1 0 0 1 1 1 0 Tap, RNA-binding zf-C2H2_jaz PF12171.8 RUS69478.1 - 5.2 7.5 9.8 3.8 7.9 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Apo-VLDL-II PF05418.11 RUS69480.1 - 0.00045 20.7 1.1 9.3 6.9 0.0 3.7 1 1 3 4 4 4 4 Apovitellenin I (Apo-VLDL-II) EFP_N PF08207.12 RUS69480.1 - 0.032 14.3 1.7 3.3 7.8 0.1 3.3 2 2 1 3 3 3 0 Elongation factor P (EF-P) KOW-like domain YqaJ PF09588.10 RUS69480.1 - 0.51 10.5 5.8 3.9 7.6 0.4 2.8 1 1 1 3 3 3 0 YqaJ-like viral recombinase domain Histone PF00125.24 RUS69481.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS69481.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS69481.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS69481.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS69481.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain RVT_1 PF00078.27 RUS69482.1 - 4.4e-13 49.3 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L37ae PF01780.19 RUS69483.1 - 0.24 11.5 0.2 0.24 11.5 0.2 1.6 2 0 0 2 2 2 0 Ribosomal L37ae protein family CENP-T_C PF15511.6 RUS69484.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 RUS69484.1 - 0.00015 21.8 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 RUS69484.1 - 0.00028 21.2 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 RUS69484.1 - 0.00054 20.3 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS69484.1 - 0.0018 18.5 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RUS69484.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RUS69484.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 RUS69485.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS69485.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS69485.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS69485.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS69485.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone PF00125.24 RUS69486.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS69486.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS69486.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS69486.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS69486.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain RVT_1 PF00078.27 RUS69487.1 - 0.00017 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD-oxidase_C PF02913.19 RUS69487.1 - 0.0052 16.4 0.0 3.4 7.2 0.0 2.2 1 1 1 2 2 2 2 FAD linked oxidases, C-terminal domain SL4P PF17618.2 RUS69487.1 - 0.12 12.4 0.0 27 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Formyl_trans_N PF00551.19 RUS69488.1 - 0.0075 16.0 0.1 4.2 7.1 0.0 2.1 2 0 0 2 2 2 2 Formyl transferase V-SNARE_C PF12352.8 RUS69488.1 - 0.15 12.4 2.0 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Histone PF00125.24 RUS69489.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS69489.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RUS69489.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 RUS69489.1 - 0.0042 17.1 0.5 0.0048 17.0 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein RP-C PF03428.13 RUS69489.1 - 0.07 12.8 0.5 7.3 6.2 0.3 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Bact_lectin PF18483.1 RUS69490.1 - 0.18 11.8 0.2 0.19 11.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial lectin EB1 PF03271.17 RUS69491.1 - 1.7e-15 56.9 0.7 4.8e-15 55.5 0.7 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 RUS69491.1 - 1.3e-14 54.3 0.1 2.1e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS69491.1 - 0.00051 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 RUS69491.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Proteasome PF00227.26 RUS69492.1 - 1.1e-37 129.4 0.0 1.3e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Topoisom_bac PF01131.20 RUS69493.1 - 7.8e-115 384.2 0.0 1.1e-114 383.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 RUS69493.1 - 6.2e-36 122.2 18.1 3.8e-18 65.3 0.7 3.9 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 RUS69493.1 - 8.6e-18 64.5 0.0 2.2e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 RUS69493.1 - 9e-12 44.6 2.1 9e-12 44.6 2.1 3.7 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 RUS69493.1 - 0.0045 17.5 2.3 0.0045 17.5 2.3 3.9 4 0 0 4 4 4 1 Recombinase zinc beta ribbon domain zf-C2H2_10 PF16588.5 RUS69493.1 - 0.2 11.4 5.3 0.57 9.9 1.7 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger Ogr_Delta PF04606.12 RUS69493.1 - 0.97 9.5 10.4 0.1 12.6 0.5 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger MFS_1 PF07690.16 RUS69494.1 - 0.0014 17.6 16.1 0.0014 17.6 16.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Ser_hydrolase PF06821.13 RUS69494.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase VWA PF00092.28 RUS69496.1 - 2e-41 142.2 1.4 2e-41 142.2 1.4 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS69496.1 - 6.2e-16 59.0 0.2 3e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS69496.1 - 1.4e-07 31.6 0.0 8.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.11 RUS69496.1 - 0.00095 18.4 0.1 0.0048 16.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1194) vWA-TerF-like PF10138.9 RUS69496.1 - 0.0047 17.1 0.3 0.011 15.8 0.1 1.8 2 1 0 2 2 2 1 vWA found in TerF C terminus Serglycin PF04360.12 RUS69496.1 - 0.052 13.5 0.1 0.052 13.5 0.1 1.9 2 0 0 2 2 2 0 Serglycin DUF531 PF04407.12 RUS69496.1 - 0.092 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) DOT1 PF08123.13 RUS69496.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Med15 PF09606.10 RUS69496.1 - 2.5 6.7 19.7 3.8 6.1 19.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraT PF05818.12 RUS69496.1 - 2.9 7.5 9.8 6.2 6.5 9.8 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Lipase_GDSL_2 PF13472.6 RUS69497.1 - 3.5e-19 69.9 0.0 5.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RUS69497.1 - 1.9e-18 67.2 0.0 6.8e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase COMM_domain PF07258.14 RUS69498.1 - 1.4e-13 50.8 0.3 2.4e-13 50.0 0.3 1.3 1 0 0 1 1 1 1 COMM domain UcrQ PF02939.16 RUS69499.1 - 2.8e-34 116.9 0.2 3.1e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 RUS69499.1 - 9e-05 22.8 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 PBP1_TM PF14812.6 RUS69500.1 - 5.3 7.5 7.7 1.5 9.3 0.0 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_tran PF00005.27 RUS69501.1 - 9.5e-54 181.6 0.0 7.5e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RUS69501.1 - 1.3e-46 159.5 10.2 3.5e-40 138.4 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RUS69501.1 - 1.8e-11 43.9 0.7 0.027 13.9 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RUS69501.1 - 5.8e-07 30.0 0.0 0.025 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RUS69501.1 - 1.6e-05 24.6 0.1 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RUS69501.1 - 4.4e-05 23.5 0.3 0.014 15.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS69501.1 - 6.6e-05 22.9 0.4 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS69501.1 - 8.1e-05 22.9 1.2 0.48 10.7 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 RUS69501.1 - 0.00022 21.1 1.2 1.3 8.7 0.0 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 RUS69501.1 - 0.002 18.2 1.5 0.49 10.4 0.6 2.5 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 RUS69501.1 - 0.0047 17.5 0.5 0.46 11.0 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RUS69501.1 - 0.0093 15.5 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 RUS69501.1 - 0.016 14.8 0.9 1.7 8.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 RUS69501.1 - 0.016 14.9 0.6 10 5.8 0.1 3.4 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 RUS69501.1 - 0.033 14.3 0.3 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 RUS69501.1 - 0.033 13.3 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 RUS69501.1 - 0.04 13.1 0.1 0.94 8.6 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain Roc PF08477.13 RUS69501.1 - 0.053 13.8 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 RUS69501.1 - 0.057 12.8 0.2 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 RUS69501.1 - 0.073 13.5 0.1 6.1 7.3 0.0 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 RUS69501.1 - 0.075 13.4 1.3 1.3 9.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 RUS69501.1 - 0.085 11.9 0.1 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 RUS69501.1 - 0.21 11.8 1.1 4 7.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS69501.1 - 0.24 11.1 0.5 9.3 5.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 RUS69502.1 - 3.7e-14 53.0 0.2 4.8e-14 52.7 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Adeno_E3_14_5 PF04834.12 RUS69502.1 - 0.032 14.8 0.1 0.059 13.9 0.1 1.4 1 0 0 1 1 1 0 Early E3 14.5 kDa protein CUB PF00431.20 RUS69504.1 - 3.9e-18 65.8 0.1 4.8e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 CUB domain Lysyl_oxidase PF01186.17 RUS69504.1 - 0.0026 17.5 0.0 0.0075 15.9 0.0 1.6 2 0 0 2 2 2 1 Lysyl oxidase CUB PF00431.20 RUS69505.1 - 1.3e-14 54.5 0.0 1.3e-06 28.7 0.0 3.2 3 0 0 3 3 3 2 CUB domain RNase_T PF00929.24 RUS69506.1 - 7.4e-34 117.7 0.0 1e-33 117.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DHHC PF01529.20 RUS69508.1 - 1.3e-26 93.3 9.7 1.3e-26 93.3 9.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase CLIP_SPH_mas PF18398.1 RUS69509.1 - 0.36 11.3 6.0 2e+02 2.5 0.0 4.9 5 0 0 5 5 5 0 Clip-domain serine protease homolog masquerade Granulin PF00396.18 RUS69509.1 - 2.9 8.3 14.0 1.2e+02 3.1 0.1 5.0 5 0 0 5 5 5 0 Granulin Pex19 PF04614.12 RUS69510.1 - 8.2e-09 35.6 0.1 1.4e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Pex19 protein family NDUFB11 PF17250.2 RUS69510.1 - 0.078 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit CDC45 PF02724.14 RUS69513.1 - 0.042 12.1 18.1 0.051 11.9 18.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS69513.1 - 1.5 6.9 30.0 1.9 6.6 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family HD PF01966.22 RUS69514.1 - 4.1e-06 27.0 0.0 1.5e-05 25.2 0.0 1.9 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 RUS69514.1 - 0.0008 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Aminotran_5 PF00266.19 RUS69515.1 - 2.2e-79 267.1 0.0 2.7e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RUS69515.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RUS69515.1 - 0.00019 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 RUS69515.1 - 0.0062 15.3 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.19 RUS69515.1 - 0.14 12.2 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain AAA_9 PF12781.7 RUS69516.1 - 6.7e-91 303.3 0.4 3.2e-90 301.1 0.5 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RUS69516.1 - 8.7e-62 207.8 0.7 2.2e-61 206.4 0.7 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 RUS69516.1 - 6.1e-55 186.6 0.0 7.5e-35 120.6 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain MT PF12777.7 RUS69516.1 - 2.1e-48 165.2 0.1 3.3e-48 164.5 0.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS69516.1 - 1.3e-35 122.1 0.0 1.4e-32 112.3 0.0 3.0 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain DUF3833 PF12915.7 RUS69516.1 - 0.01 15.5 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3833) DHR10 PF18595.1 RUS69516.1 - 0.43 10.6 13.2 0.066 13.3 6.7 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 RUS69516.1 - 1.5 9.3 14.6 4.7 7.7 0.7 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 RUS69516.1 - 2.3 7.0 15.4 0.098 11.5 4.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3932 PF13068.6 RUS69517.1 - 0.098 13.0 0.4 23 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) YqjK PF13997.6 RUS69517.1 - 0.1 12.8 0.0 23 5.3 0.0 2.4 2 0 0 2 2 2 0 YqjK-like protein APC_r PF05923.12 RUS69517.1 - 0.11 12.3 0.6 21 5.0 0.1 2.5 2 0 0 2 2 2 0 APC repeat Carn_acyltransf PF00755.20 RUS69518.1 - 3.3e-182 607.2 0.0 3.7e-182 607.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MG1 PF17790.1 RUS69519.1 - 6.7e-11 42.5 0.2 83 3.7 0.0 9.5 1 1 9 10 10 10 1 Macroglobulin domain MG1 CLIP PF12032.8 RUS69519.1 - 0.011 15.9 20.1 6.7 7.1 0.4 7.8 1 1 7 8 8 8 0 Regulatory CLIP domain of proteinases SGS PF05002.15 RUS69520.1 - 1.6e-06 28.1 1.9 3.1e-06 27.2 1.9 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 RUS69520.1 - 0.0028 18.6 0.9 0.0039 18.2 0.9 1.2 1 0 0 1 1 1 1 CS domain DEFB136 PF17333.2 RUS69521.1 - 1.6e-07 31.2 48.6 0.34 10.9 0.4 8.8 8 0 0 8 8 8 8 Beta defensin 136 Laminin_EGF PF00053.24 RUS69521.1 - 0.033 14.3 168.2 39 4.5 18.1 10.2 1 1 9 10 10 10 0 Laminin EGF domain IMPDH PF00478.25 RUS69525.1 - 6.2e-139 462.8 5.7 8.1e-139 462.4 5.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 RUS69525.1 - 1.8e-10 41.1 0.1 0.00035 21.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 RUS69525.1 - 1.1e-08 34.9 8.5 5.7e-06 25.9 4.7 2.4 1 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 RUS69525.1 - 1.9e-08 33.7 0.9 3.6e-08 32.8 0.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 RUS69525.1 - 1.1e-07 31.6 2.4 8.9e-06 25.3 0.3 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 RUS69525.1 - 0.00032 20.1 1.3 0.00065 19.1 1.1 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 RUS69525.1 - 0.00046 19.4 0.7 0.0014 17.9 0.7 1.9 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 RUS69525.1 - 0.012 14.8 1.1 0.68 9.0 0.0 2.2 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 RUS69525.1 - 0.013 14.6 2.1 0.027 13.6 2.1 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF561 PF04481.12 RUS69525.1 - 0.06 12.5 1.5 0.11 11.7 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF561) DHO_dh PF01180.21 RUS69525.1 - 0.062 12.5 0.3 0.062 12.5 0.3 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase 7tm_1 PF00001.21 RUS69526.1 - 3.4e-65 220.0 0.0 6.4e-65 219.1 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS69526.1 - 0.00042 20.0 7.1 0.00086 19.0 7.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS69526.1 - 0.005 16.2 10.2 0.12 11.8 5.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RUS69526.1 - 0.69 9.6 4.5 0.22 11.2 1.8 1.5 2 0 0 2 2 2 0 Olfactory receptor ATP_bind_3 PF01171.20 RUS69527.1 - 4.5e-14 52.6 0.0 1.2e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 PP-loop family Aminotran_5 PF00266.19 RUS69527.1 - 1.4e-11 44.0 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF4147 PF13660.6 RUS69527.1 - 0.16 11.5 0.0 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) PEX11 PF05648.14 RUS69528.1 - 0.075 12.5 0.2 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Nucleos_tra2_N PF01773.20 RUS69530.1 - 3e-22 79.0 0.8 3e-22 79.0 0.8 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS69530.1 - 1.6e-09 38.0 12.4 3.3e-07 30.6 9.2 3.2 3 1 0 3 3 3 2 Nucleoside recognition mRNA_cap_C PF03919.15 RUS69531.1 - 0.075 13.7 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain PspB PF06667.12 RUS69531.1 - 0.33 11.1 1.4 0.86 9.7 0.1 2.1 1 1 1 2 2 2 0 Phage shock protein B SlyX PF04102.12 RUS69531.1 - 0.65 10.7 4.4 8.9 7.0 1.1 2.4 1 1 1 2 2 2 0 SlyX HEPN PF05168.14 RUS69532.1 - 0.041 14.0 0.0 0.06 13.5 0.0 1.1 1 0 0 1 1 1 0 HEPN domain IPPT PF01715.17 RUS69532.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 IPP transferase Snapin_Pallidin PF14712.6 RUS69532.1 - 0.11 12.9 0.5 0.17 12.3 0.5 1.2 1 0 0 1 1 1 0 Snapin/Pallidin ANAPC4_WD40 PF12894.7 RUS69533.1 - 9.4e-07 29.0 0.1 0.028 14.7 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 RUS69533.1 - 0.023 13.9 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 T6SS_HCP PF05638.12 RUS69533.1 - 0.11 13.0 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system effector, Hcp Sugar_tr PF00083.24 RUS69534.1 - 7.4e-40 137.2 6.3 8.4e-40 137.0 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS69534.1 - 2.6e-12 46.4 8.2 3.2e-12 46.1 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 RUS69534.1 - 0.002 17.1 0.3 0.0027 16.7 0.3 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 RUS69534.1 - 0.89 10.1 5.7 0.14 12.7 1.5 1.9 2 1 0 2 2 2 0 Phage holin family 2 DNA_pol3_alpha PF07733.12 RUS69535.1 - 2.1e-97 325.8 0.0 3.2e-97 325.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 RUS69535.1 - 4.5e-63 211.5 0.1 1.4e-62 210.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain COE1_HLH PF16423.5 RUS69535.1 - 0.04 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain ACCA PF03255.14 RUS69536.1 - 5.2e-57 191.8 0.8 1.4e-56 190.3 0.0 2.2 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 RUS69536.1 - 4.9e-15 55.1 0.1 9.6e-15 54.2 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain SIS_2 PF13580.6 RUS69536.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 SIS domain D5_N PF08706.11 RUS69536.1 - 0.042 14.1 0.9 0.12 12.6 0.9 1.8 1 0 0 1 1 1 0 D5 N terminal like TraG-D_C PF12696.7 RUS69536.1 - 5.1 7.1 9.5 0.09 12.8 0.5 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Na_H_Exchanger PF00999.21 RUS69537.1 - 1.5e-50 172.1 40.4 1.8e-50 171.8 40.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DnaJ_C PF01556.18 RUS69538.1 - 6e-30 104.3 0.2 8.2e-30 103.8 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS69538.1 - 8.9e-26 89.8 2.7 1.6e-25 89.0 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 RUS69538.1 - 0.16 12.6 0.1 0.27 11.9 0.1 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI AA_permease_2 PF13520.6 RUS69539.1 - 3.5e-42 144.7 46.1 3.8e-42 144.6 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS69539.1 - 9.2e-25 87.2 45.0 1.1e-24 86.9 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease Lectin_C PF00059.21 RUS69541.1 - 3.6e-22 79.1 0.0 2e-12 47.8 0.0 2.8 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 RUS69541.1 - 1.9e-05 24.4 0.3 0.0039 16.9 0.0 2.8 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Furin-like_2 PF15913.5 RUS69541.1 - 0.0087 16.2 0.8 0.023 14.9 0.2 1.9 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich Chordopox_A33R PF05966.12 RUS69541.1 - 0.038 13.3 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Homeodomain PF00046.29 RUS69542.1 - 6.6e-23 80.3 7.7 9.5e-23 79.8 7.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS69542.1 - 0.19 11.7 0.7 0.47 10.4 0.7 1.8 1 1 0 1 1 1 0 Homeobox KN domain Pex19 PF04614.12 RUS69543.1 - 0.052 13.3 4.3 1.4 8.6 1.3 2.4 2 0 0 2 2 2 0 Pex19 protein family Calpain_inhib PF00748.19 RUS69543.1 - 0.18 12.3 1.4 1.2 9.6 0.1 2.1 2 0 0 2 2 2 0 Calpain inhibitor DSL PF01414.19 RUS69544.1 - 9 6.7 26.4 1.5 9.1 2.3 2.4 1 1 0 2 2 2 0 Delta serrate ligand Somatomedin_B PF01033.17 RUS69545.1 - 4e-08 33.5 10.7 4e-08 33.5 10.7 2.1 2 0 0 2 2 2 1 Somatomedin B domain VWD PF00094.25 RUS69546.1 - 0.034 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type D domain Toxin_2 PF00451.19 RUS69547.1 - 0.037 14.3 18.7 21 5.5 0.0 5.4 5 0 0 5 5 5 0 Scorpion short toxin, BmKK2 TFB6 PF17110.5 RUS69547.1 - 0.049 13.4 2.4 39 3.9 0.0 3.8 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Fer4_3 PF12798.7 RUS69547.1 - 0.078 14.0 34.0 1.5 9.9 1.3 5.4 5 0 0 5 5 5 0 4Fe-4S binding domain zf-RING_13 PF17977.1 RUS69547.1 - 0.09 12.9 14.1 4.8 7.4 0.4 4.0 1 1 3 4 4 4 0 RING/Ubox like zinc-binding domain PA_decarbox PF05870.11 RUS69547.1 - 0.15 11.7 2.9 1.7 8.2 0.1 2.7 1 1 1 2 2 2 0 Phenolic acid decarboxylase (PAD) Phycoerythr_ab PF02972.14 RUS69547.1 - 1.3 8.9 11.7 9.6 6.1 0.1 4.6 5 0 0 5 5 5 0 Phycoerythrin, alpha/beta chain Notch PF00066.17 RUS69547.1 - 1.7 9.1 20.8 3.6 8.1 0.2 4.3 4 1 1 5 5 5 0 LNR domain TSP_1 PF00090.19 RUS69548.1 - 1.1 9.5 5.5 1.7 8.9 3.3 2.5 2 0 0 2 2 2 0 Thrombospondin type 1 domain TPR_12 PF13424.6 RUS69551.1 - 8.3e-05 22.8 7.2 1.3 9.4 0.1 6.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS69551.1 - 9.6e-05 22.2 4.0 24 5.4 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS69551.1 - 0.00039 20.9 1.0 0.76 10.3 0.0 5.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS69551.1 - 0.00093 19.7 0.9 0.069 13.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HEAT_2 PF13646.6 RUS69551.1 - 0.0017 18.7 0.0 0.0048 17.3 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats TPR_1 PF00515.28 RUS69551.1 - 0.0094 15.7 4.7 82 3.3 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Sdh5 PF03937.16 RUS69551.1 - 0.014 15.4 0.2 2 8.5 0.0 3.4 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase TPR_14 PF13428.6 RUS69551.1 - 0.039 14.8 4.5 5.2 8.2 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 RUS69551.1 - 1.6 8.7 4.4 0.5 10.3 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit ANAPC15 PF15243.6 RUS69552.1 - 0.4 11.1 2.9 1 9.8 2.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 RNA_pol_Rpc4 PF05132.14 RUS69553.1 - 0.0011 19.5 15.4 0.0013 19.2 15.4 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 AAA_11 PF13086.6 RUS69553.1 - 0.0012 18.7 15.5 0.0015 18.4 15.5 1.2 1 0 0 1 1 1 1 AAA domain CDC45 PF02724.14 RUS69553.1 - 0.0017 16.7 20.0 0.0018 16.7 20.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3807 PF12720.7 RUS69553.1 - 0.003 17.9 26.1 0.0041 17.4 26.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 RUS69553.1 - 0.0037 17.1 22.3 0.0043 16.9 22.3 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RUS69553.1 - 0.0047 17.1 7.1 0.0051 17.0 7.1 1.2 1 0 0 1 1 1 1 DDHD domain Otopetrin PF03189.13 RUS69553.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.3 1 1 0 1 1 1 0 Otopetrin SLC12 PF03522.15 RUS69553.1 - 0.034 13.2 15.0 0.037 13.0 15.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 RUS69553.1 - 0.036 13.5 17.5 0.054 12.9 17.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 RUS69553.1 - 0.055 13.6 20.2 0.072 13.2 20.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DAG_kinase_N PF14513.6 RUS69553.1 - 0.08 13.1 13.0 0.1 12.8 13.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SRP-alpha_N PF04086.13 RUS69553.1 - 0.084 12.8 30.5 0.1 12.5 30.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM_bind PF09739.9 RUS69553.1 - 0.16 10.4 17.0 0.17 10.3 17.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SID-1_RNA_chan PF13965.6 RUS69553.1 - 0.27 9.6 1.4 0.26 9.6 1.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Vfa1 PF08432.10 RUS69553.1 - 0.71 10.2 38.1 1.4 9.2 38.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5308 PF17233.2 RUS69553.1 - 1.3 9.2 4.8 1.8 8.8 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF913 PF06025.12 RUS69553.1 - 1.4 7.8 8.9 1.6 7.6 8.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VIR_N PF15912.5 RUS69553.1 - 1.6 8.2 9.9 1.9 8.0 9.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PTPRCAP PF15713.5 RUS69553.1 - 1.9 8.8 15.9 3.1 8.1 15.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Paramyxo_ncap PF00973.19 RUS69553.1 - 2 7.3 10.8 2.3 7.0 10.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.7 RUS69553.1 - 2.2 6.3 10.8 2.4 6.2 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4228 PF14009.6 RUS69553.1 - 3.6 7.9 18.3 5.6 7.3 18.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Tim54 PF11711.8 RUS69553.1 - 6 5.5 25.5 9.4 4.9 25.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SOBP PF15279.6 RUS69553.1 - 6.2 7.3 12.6 8.3 6.9 12.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Afi1 PF07792.12 RUS69553.1 - 8.9 6.8 19.1 17 5.9 19.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ALMT PF11744.8 RUS69553.1 - 9.9 4.9 18.3 15 4.3 18.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LRAT PF04970.13 RUS69555.1 - 1.5e-24 86.7 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF4894 PF16235.5 RUS69555.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) RVT_1 PF00078.27 RUS69556.1 - 2.5e-11 43.5 0.0 3.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mpp10 PF04006.12 RUS69556.1 - 0.0034 15.9 7.5 0.0039 15.7 7.5 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2796 PF10986.8 RUS69556.1 - 0.99 9.3 4.0 0.75 9.7 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) RNase_H2_suC PF08615.11 RUS69556.1 - 1.9 8.6 4.8 13 5.9 4.6 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CobT PF06213.12 RUS69556.1 - 3.4 7.0 18.5 4.9 6.5 18.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 RUS69556.1 - 5.4 6.0 42.0 9 5.3 42.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAM_PNT PF02198.16 RUS69561.1 - 1.7e-07 31.1 0.1 4.8e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain MNNL PF07657.13 RUS69561.1 - 6.3 6.9 7.9 5.3 7.2 0.5 3.7 4 0 0 4 4 4 0 N terminus of Notch ligand Ets PF00178.22 RUS69562.1 - 4.3e-36 123.2 0.3 6.6e-36 122.6 0.3 1.3 1 0 0 1 1 1 1 Ets-domain Neur_chan_LBD PF02931.23 RUS69563.1 - 5.9e-44 150.1 0.2 7.6e-44 149.7 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS69563.1 - 7.8e-11 42.5 2.0 1.3e-10 41.8 2.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF727 PF05303.12 RUS69564.1 - 1.7e-30 105.2 0.5 2.1e-30 104.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) SH2_2 PF14633.6 RUS69564.1 - 0.038 13.4 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 SH2 domain TRAPPC10 PF12584.8 RUS69565.1 - 6.7e-12 45.4 0.0 2.1e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 RUS69565.1 - 5.5e-06 26.2 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 SNAP PF14938.6 RUS69565.1 - 0.018 14.4 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP 7tm_1 PF00001.21 RUS69566.1 - 5.6e-47 160.3 17.2 7.6e-47 159.8 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FragX_IP PF05994.11 RUS69566.1 - 0.066 11.3 0.0 0.092 10.8 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family FAM176 PF14851.6 RUS69566.1 - 0.44 10.2 1.6 1.1 8.9 1.6 1.8 1 0 0 1 1 1 0 FAM176 family Yip1 PF04893.17 RUS69566.1 - 0.74 9.5 15.6 4.2 7.1 6.9 2.7 2 1 0 2 2 2 0 Yip1 domain Tmem26 PF09772.9 RUS69567.1 - 4.4e-69 233.0 11.6 3.1e-53 181.0 5.9 2.1 2 0 0 2 2 2 2 Transmembrane protein 26 Renin_r PF07850.14 RUS69567.1 - 0.13 12.9 0.4 0.7 10.5 0.0 2.4 2 0 0 2 2 2 0 Renin receptor-like protein GPI2 PF06432.11 RUS69567.1 - 1 8.7 10.8 0.02 14.3 2.1 2.3 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase FHA PF00498.26 RUS69568.1 - 1.4e-17 63.8 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS69568.1 - 6.8e-06 26.3 0.0 2.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dicer_dimer PF03368.14 RUS69568.1 - 0.0015 18.6 0.0 0.0046 17.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain DUF2959 PF11172.8 RUS69568.1 - 0.0017 18.5 1.0 0.0039 17.3 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) LPD28 PF18843.1 RUS69568.1 - 0.052 13.2 0.4 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 28 F_actin_bind PF08919.10 RUS69568.1 - 0.056 13.5 0.9 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 F-actin binding SpoIISA_toxin PF14171.6 RUS69568.1 - 0.23 11.1 0.5 0.57 9.8 0.5 1.6 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system FapA PF03961.13 RUS69568.1 - 0.71 8.4 9.4 0.031 12.9 2.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A CLN3 PF02487.17 RUS69569.1 - 1.3e-136 455.8 22.5 6.4e-135 450.2 22.5 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 RUS69569.1 - 1.2e-05 24.4 26.4 7.5e-05 21.8 25.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily CaATP_NAI PF12515.8 RUS69570.1 - 7.8e-06 25.4 11.0 14 5.4 0.0 7.3 7 0 0 7 7 7 2 Ca2+-ATPase N terminal autoinhibitory domain NSs PF11073.8 RUS69570.1 - 0.0036 16.8 0.0 1.5 8.2 0.0 3.0 1 1 2 3 3 3 1 Rift valley fever virus non structural protein (NSs) like Alpha-2-MRAP_N PF06400.11 RUS69570.1 - 0.014 15.4 0.6 19 5.3 0.0 4.7 2 1 5 7 7 7 0 Alpha-2-macroglobulin RAP, N-terminal domain PCSK9_C3 PF18463.1 RUS69570.1 - 0.15 12.3 11.4 1.7 8.9 0.1 4.1 2 2 2 4 4 4 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain BACK PF07707.15 RUS69570.1 - 0.45 10.6 4.2 21 5.3 0.0 4.0 2 2 3 5 5 5 0 BTB And C-terminal Kelch Thg1C PF14413.6 RUS69570.1 - 1.1 9.5 4.0 61 3.8 0.0 4.5 6 0 0 6 6 6 0 Thg1 C terminal domain Phostensin_N PF13916.6 RUS69572.1 - 0.012 15.9 8.1 0.016 15.5 1.9 2.9 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal MRP-L51 PF10244.9 RUS69573.1 - 9.8e-30 102.6 0.4 1.4e-29 102.1 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit DUF3085 PF11284.8 RUS69573.1 - 0.15 12.4 0.1 25 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) DNA_pol_E_B PF04042.16 RUS69574.1 - 0.93 8.8 3.2 0.32 10.3 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Glycolytic PF00274.19 RUS69575.1 - 6e-143 475.8 0.0 2.6e-101 338.8 0.0 2.0 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-I zf-LITAF-like PF10601.9 RUS69577.1 - 3.4e-21 75.3 10.9 4.1e-21 75.0 10.9 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sec5 PF15469.6 RUS69578.1 - 0.05 13.4 0.1 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Glycos_transf_2 PF00535.26 RUS69581.1 - 6.9e-32 110.6 0.0 1.4e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS69581.1 - 8.5e-19 68.1 0.3 1.3e-18 67.4 0.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RUS69581.1 - 2e-06 27.9 0.0 5.2e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS69581.1 - 5.1e-06 26.1 0.3 1.1e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS69581.1 - 5.8e-05 22.7 0.0 0.00018 21.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RUS69581.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 NUC153 PF08159.12 RUS69583.1 - 1.8e-12 46.9 0.7 4.2e-12 45.7 0.7 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 RUS69583.1 - 0.0017 19.2 0.0 7 7.7 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS69583.1 - 0.14 12.5 0.0 0.89 9.9 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Phage_Gp111 PF07410.11 RUS69583.1 - 2.2 8.8 6.5 0.2 12.1 0.8 2.2 3 0 0 3 3 3 0 Streptococcus thermophilus bacteriophage Gp111 protein tRNA-synt_2d PF01409.20 RUS69584.1 - 5.5e-91 304.4 0.1 7.9e-91 303.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 RUS69584.1 - 1e-20 73.2 1.1 2.8e-20 71.8 1.1 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 RUS69584.1 - 1.9e-20 72.9 0.8 1.9e-20 72.9 0.8 2.6 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 RUS69584.1 - 1.6e-11 44.0 2.1 4e-11 42.7 2.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 RUS69584.1 - 5.2e-09 35.9 0.0 1.4e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain HTH_11 PF08279.12 RUS69584.1 - 6.7e-06 25.9 0.1 1.6e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 HTH domain tRNA-synt_2 PF00152.20 RUS69584.1 - 0.00067 18.8 0.2 0.0021 17.2 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) MarR PF01047.22 RUS69584.1 - 0.0043 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 MarR family tRNA-synt_2b PF00587.25 RUS69584.1 - 0.0045 17.0 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_1 PF00126.27 RUS69584.1 - 0.0075 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_17 PF12728.7 RUS69584.1 - 0.044 14.0 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_pRha PF09669.10 RUS69584.1 - 0.063 13.8 0.7 0.33 11.6 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) MarR_2 PF12802.7 RUS69584.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 MarR family Put_DNA-bind_N PF06971.13 RUS69584.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus DUF2666 PF10869.8 RUS69584.1 - 0.84 9.9 4.4 0.71 10.1 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2666) Lactamase_B_6 PF16661.5 RUS69585.1 - 1.4e-26 93.1 0.0 3.7e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 RUS69585.1 - 7.3e-26 90.6 0.0 1.6e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 RUS69585.1 - 1.9e-19 69.3 0.0 4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 RUS69585.1 - 3.2e-12 46.9 0.1 3.1e-11 43.7 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS69585.1 - 1.3e-09 37.9 0.9 1.2e-08 34.7 0.1 2.4 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RUS69585.1 - 4.8e-06 26.0 0.0 1.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 RUS69585.1 - 6.8e-06 26.1 0.0 3e-05 24.0 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain AIRS_C PF02769.22 RUS69586.1 - 1.3e-27 96.8 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Clat_adaptor_s PF01217.20 RUS69587.1 - 5.2e-51 172.3 2.1 6.5e-51 172.0 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UPAR_LY6_2 PF16975.5 RUS69588.1 - 0.00056 20.1 14.7 0.00089 19.4 14.7 1.3 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 RNA_pol_Rpc34 PF05158.12 RUS69588.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit ecTbetaR2 PF08917.10 RUS69588.1 - 0.055 13.4 14.7 0.075 13.0 14.7 1.2 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain 7tm_1 PF00001.21 RUS69591.1 - 2.9e-23 82.5 0.9 3.5e-23 82.3 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FtsX PF02687.21 RUS69591.1 - 0.038 14.5 2.1 0.12 12.8 1.2 2.1 2 0 0 2 2 2 0 FtsX-like permease family Phage_holin_3_5 PF16085.5 RUS69591.1 - 0.081 13.1 1.9 0.084 13.0 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III NICE-3 PF07406.11 RUS69591.1 - 0.22 11.5 1.7 0.25 11.3 0.4 1.7 2 0 0 2 2 2 0 NICE-3 protein S1FA PF04689.13 RUS69591.1 - 0.47 10.6 1.9 4.5 7.5 0.2 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA FixQ PF05545.11 RUS69591.1 - 0.86 9.6 3.4 0.72 9.9 0.7 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PRA1 PF03208.19 RUS69591.1 - 1.4 8.6 8.9 0.48 10.0 0.3 2.8 3 0 0 3 3 3 0 PRA1 family protein HemY_N PF07219.13 RUS69591.1 - 8.7 6.6 6.7 0.58 10.4 0.3 2.3 3 0 0 3 3 3 0 HemY protein N-terminus zf-H2C2_2 PF13465.6 RUS69592.1 - 1.2e-30 104.5 48.9 3.4e-07 30.4 0.1 9.1 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS69592.1 - 9.4e-26 88.8 65.1 4.5e-05 23.7 2.2 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69592.1 - 1e-19 69.5 60.3 0.00087 19.9 1.8 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS69592.1 - 8.8e-07 29.1 29.5 0.047 14.0 0.3 7.7 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS69592.1 - 0.0002 21.0 38.5 0.0071 16.1 1.7 6.6 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-met PF12874.7 RUS69592.1 - 0.0023 18.3 44.8 0.053 13.9 0.3 8.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type C1_4 PF07975.12 RUS69592.1 - 0.0099 16.1 2.1 0.0099 16.1 2.1 5.1 3 1 0 4 4 4 1 TFIIH C1-like domain FYDLN_acid PF09538.10 RUS69592.1 - 0.037 14.7 0.1 0.037 14.7 0.1 6.9 6 2 3 10 10 9 0 Protein of unknown function (FYDLN_acid) DUF4718 PF15842.5 RUS69592.1 - 0.045 13.6 0.6 0.15 11.8 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) CRM1_repeat_2 PF18784.1 RUS69592.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 DUF3268 PF11672.8 RUS69592.1 - 0.28 11.5 22.4 0.34 11.2 1.3 4.5 4 0 0 4 4 4 0 zinc-finger-containing domain DNA_pol3_chi PF04364.13 RUS69592.1 - 0.35 11.0 1.8 14 5.8 0.3 2.7 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC zf-C2H2_9 PF16293.5 RUS69592.1 - 4.5 7.2 10.4 6 6.8 0.4 3.9 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 RUS69592.1 - 6.5 7.3 6.3 68 4.1 0.1 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 RUS69592.1 - 9.4 6.5 29.4 3.8 7.7 3.0 6.2 4 2 2 6 6 6 0 Zinc ribbon domain Peptidase_S24 PF00717.23 RUS69593.1 - 4.9e-10 39.2 0.1 7.5e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF2457 PF10446.9 RUS69594.1 - 2.6e-05 23.6 46.6 3.4e-05 23.2 46.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.12 RUS69594.1 - 0.009 15.5 29.5 0.01 15.3 29.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS69594.1 - 0.02 13.2 30.9 0.024 12.9 30.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS69594.1 - 0.021 14.2 22.5 0.022 14.1 22.5 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 RUS69594.1 - 0.31 9.8 2.1 0.38 9.5 2.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 RUS69594.1 - 3.5 6.3 7.5 4 6.1 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UNC-93 PF05978.16 RUS69595.1 - 8.7e-10 38.5 7.0 8.7e-10 38.5 7.0 3.1 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 Tcp10_C PF07202.13 RUS69597.1 - 7.6e-15 55.3 3.3 1.2e-07 31.9 0.4 2.0 1 1 1 2 2 2 2 T-complex protein 10 C-terminus MazG_C PF18722.1 RUS69597.1 - 2e-07 30.7 0.5 0.71 9.3 0.0 3.8 1 1 4 5 5 5 4 MazG C-terminal domain Csd3_N PF18059.1 RUS69597.1 - 1.1e-06 29.1 5.6 5.3 7.6 0.1 6.7 1 1 6 7 7 7 1 Csd3 N-terminal CopK PF11525.8 RUS69597.1 - 3.6e-06 26.5 16.1 2.6 7.7 0.3 7.0 1 1 7 9 9 9 3 Copper resistance protein K Acid_PPase PF12689.7 RUS69597.1 - 0.00014 21.8 1.9 13 5.6 0.1 4.7 1 1 3 4 4 4 1 Acid Phosphatase Plasmodium_HRP PF05403.11 RUS69597.1 - 0.00076 19.3 13.2 0.0015 18.4 13.2 1.5 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) DUF5636 PF18686.1 RUS69597.1 - 0.0028 17.9 4.4 8.4 6.5 4.4 3.2 1 1 0 1 1 1 1 Family of unknown function (DUF5636) SSF PF00474.17 RUS69597.1 - 0.02 13.8 0.0 18 4.1 0.0 3.4 1 1 2 3 3 3 0 Sodium:solute symporter family DIT1_PvcA PF05141.12 RUS69597.1 - 0.034 13.6 3.4 14 5.1 0.1 3.6 1 1 2 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein Methyltransf_22 PF13383.6 RUS69597.1 - 0.044 13.3 11.3 3.8 7.0 0.4 3.2 1 1 2 3 3 3 0 Methyltransferase domain TGT_C2 PF14810.6 RUS69597.1 - 0.12 12.5 0.4 29 4.9 0.1 2.8 1 1 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Laterosporulin PF17861.1 RUS69597.1 - 0.7 10.3 8.5 11 6.5 0.5 4.2 1 1 2 3 3 3 0 Laterosporulin defensin-like peptide 5-nucleotidase PF06189.12 RUS69597.1 - 1.5 7.7 12.4 6.4 5.6 1.6 3.2 1 1 1 2 2 2 0 5'-nucleotidase Antimicrobial19 PF08225.11 RUS69598.1 - 3.9e-05 23.1 68.1 9.1 6.0 0.3 15.9 1 1 17 18 18 18 16 Pseudin antimicrobial peptide AAA_lid_3 PF17862.1 RUS69598.1 - 0.0078 16.0 1.2 12 5.8 0.1 5.4 2 2 1 3 3 3 1 AAA+ lid domain Pox_TAA1 PF03295.14 RUS69599.1 - 4 7.4 27.3 22 5.0 0.1 7.5 6 2 3 9 9 9 0 Poxvirus trans-activator protein A1 C-terminal DUF1065 PF06358.11 RUS69599.1 - 9.6 6.2 9.4 15 5.6 0.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1065) S100PBPR PF15427.6 RUS69600.1 - 0.013 14.8 3.7 0.022 14.0 3.7 1.3 1 0 0 1 1 1 0 S100P-binding protein AHD PF17793.1 RUS69601.1 - 0.028 14.2 0.0 25 4.8 0.0 3.4 1 1 3 4 4 4 0 ANC1 homology domain (AHD) Flu_NS2 PF00601.19 RUS69601.1 - 0.1 12.9 5.0 2.7 8.3 0.2 3.2 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) Defensin_big PF14862.6 RUS69601.1 - 0.12 12.8 16.8 6.7 7.1 0.5 5.3 1 1 5 6 6 6 0 Big defensin HisKA_2 PF07568.12 RUS69601.1 - 0.56 10.3 2.8 17 5.5 0.1 3.4 1 1 2 3 3 3 0 Histidine kinase RINGv PF12906.7 RUS69602.1 - 5.7e-16 58.4 13.8 1.8e-15 56.8 13.8 1.9 1 0 0 1 1 1 1 RING-variant domain Zip PF02535.22 RUS69602.1 - 0.0014 17.9 0.4 0.0022 17.3 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DDHD PF02862.17 RUS69602.1 - 0.0024 18.1 1.0 0.0033 17.6 1.0 1.2 1 0 0 1 1 1 1 DDHD domain Velvet PF11754.8 RUS69602.1 - 0.0024 17.8 2.8 0.0038 17.2 2.8 1.3 1 0 0 1 1 1 1 Velvet factor TFIIA PF03153.13 RUS69602.1 - 0.0026 17.8 28.0 0.0036 17.4 28.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 RUS69602.1 - 0.0036 16.3 0.0 0.0047 15.9 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3810 PF12725.7 RUS69602.1 - 0.0056 16.1 0.5 0.008 15.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) SARAF PF06682.12 RUS69602.1 - 0.0084 15.8 5.1 0.0084 15.8 5.1 1.8 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Endostatin PF06482.11 RUS69602.1 - 0.009 15.5 7.5 0.017 14.6 7.5 1.4 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin HemX PF04375.14 RUS69602.1 - 0.009 15.3 21.1 0.013 14.8 21.1 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase RNA_pol_Rbc25 PF08292.12 RUS69602.1 - 0.0095 16.2 2.6 0.016 15.4 2.6 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF4834 PF16118.5 RUS69602.1 - 0.016 16.2 5.7 0.016 16.2 5.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 RUS69602.1 - 0.019 14.7 4.2 0.036 13.8 4.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Asparaginase_2 PF01112.18 RUS69602.1 - 0.066 12.2 5.4 0.09 11.8 5.4 1.1 1 0 0 1 1 1 0 Asparaginase SpoIIP PF07454.11 RUS69602.1 - 0.08 12.4 8.8 0.11 12.0 8.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DctQ PF04290.12 RUS69602.1 - 0.084 12.8 2.1 0.12 12.2 2.1 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component UPF0242 PF06785.11 RUS69602.1 - 0.095 12.8 20.2 0.17 12.0 20.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Band_3_cyto PF07565.13 RUS69602.1 - 0.13 12.1 9.3 0.2 11.5 9.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FapA PF03961.13 RUS69602.1 - 0.17 10.5 6.3 0.22 10.1 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EPL1 PF10513.9 RUS69602.1 - 0.31 11.4 13.1 1.1 9.6 11.8 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like AAA_23 PF13476.6 RUS69602.1 - 0.5 10.8 13.7 0.73 10.3 13.7 1.3 1 0 0 1 1 1 0 AAA domain DUF3292 PF11696.8 RUS69602.1 - 0.51 8.6 7.4 0.66 8.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Spt20 PF12090.8 RUS69602.1 - 0.52 9.9 36.6 0.94 9.0 36.6 1.4 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 RUS69602.1 - 0.59 9.5 17.0 0.82 9.0 17.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAT1 PF09770.9 RUS69602.1 - 0.86 7.8 21.9 1.1 7.4 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Orf78 PF06024.12 RUS69602.1 - 0.97 9.8 9.0 35 4.8 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Gti1_Pac2 PF09729.9 RUS69602.1 - 1 9.4 7.5 1.7 8.7 7.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Pal1 PF08316.11 RUS69602.1 - 1.6 9.5 6.0 2.9 8.7 6.0 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Suf PF05843.14 RUS69602.1 - 1.8 8.5 15.0 2.6 8.0 15.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 RUS69602.1 - 1.9 8.5 20.6 3.2 7.7 20.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 RUS69602.1 - 1.9 7.4 14.8 2.7 6.9 14.8 1.1 1 0 0 1 1 1 0 Paf1 Pex14_N PF04695.13 RUS69602.1 - 2.3 8.9 26.3 1 10.0 22.6 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coilin_N PF15862.5 RUS69602.1 - 3 7.6 13.3 5.9 6.7 13.3 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF2722 PF10846.8 RUS69602.1 - 3.4 6.5 29.4 5.7 5.8 29.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spore_III_AF PF09581.10 RUS69602.1 - 3.4 7.6 10.7 5.2 7.1 10.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) eIF-3_zeta PF05091.12 RUS69602.1 - 4.2 6.2 18.5 5.9 5.8 18.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 RUS69602.1 - 4.5 7.4 10.5 7 6.8 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 RUS69602.1 - 6.6 6.5 15.4 10 5.9 15.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pentapeptide PF00805.22 RUS69603.1 - 0.0022 17.6 0.5 1.2 8.9 0.3 2.7 2 2 0 2 2 2 2 Pentapeptide repeats (8 copies) Keratin_B2_2 PF13885.6 RUS69603.1 - 0.015 15.2 25.1 6.2e+02 0.5 25.1 2.7 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Ras PF00071.22 RUS69606.1 - 4.2e-22 78.5 0.0 5.1e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS69606.1 - 5.1e-09 36.4 0.0 8.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS69606.1 - 9e-09 35.0 0.1 1.1e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 RUS69606.1 - 0.0006 20.1 0.2 0.002 18.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RUS69606.1 - 0.0026 17.8 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RUS69606.1 - 0.024 15.2 0.8 0.076 13.6 0.8 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 RUS69606.1 - 0.057 12.9 0.2 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RUS69606.1 - 0.061 12.8 0.5 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 RUS69606.1 - 0.095 12.2 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RUS69606.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 RUS69606.1 - 0.12 12.2 0.3 1.8 8.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase zf-RanBP PF00641.18 RUS69607.1 - 1.1e-10 40.6 12.8 1.8e-05 23.9 3.2 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 RUS69607.1 - 0.00027 20.9 5.2 0.001 19.1 5.3 1.9 1 1 0 1 1 1 1 Double zinc ribbon PUB PF09409.10 RUS69607.1 - 0.0032 17.4 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain zinc_ribbon_15 PF17032.5 RUS69607.1 - 0.12 13.1 1.5 8.6 7.2 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon family GAS PF13851.6 RUS69608.1 - 2.9e-82 274.9 34.8 2.9e-82 274.9 34.8 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 RUS69608.1 - 0.0007 17.3 58.7 0.00091 16.9 58.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Virulence_fact PF13769.6 RUS69608.1 - 0.084 13.1 0.3 0.084 13.1 0.3 4.2 4 1 0 5 5 5 0 Virulence factor Metal_resist PF13801.6 RUS69608.1 - 0.1 12.8 0.1 0.1 12.8 0.1 5.3 4 3 1 5 5 5 0 Heavy-metal resistance Flg_hook PF02120.16 RUS69608.1 - 0.15 12.0 5.7 3.3 7.7 0.2 3.7 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK DUF948 PF06103.11 RUS69608.1 - 2.7 8.3 15.4 6 7.2 0.1 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RUS69608.1 - 4.3 7.4 20.3 0.45 10.6 1.9 4.0 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WH1 PF00568.23 RUS69609.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 WH1 domain AAA_6 PF12774.7 RUS69610.1 - 1e-52 179.2 0.4 9.4e-44 149.7 0.0 4.2 4 0 0 4 4 3 3 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RUS69610.1 - 3.6e-47 160.2 0.4 1.2e-41 142.2 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 RUS69610.1 - 4.6e-41 140.8 0.5 1.5e-38 132.6 0.0 3.6 3 1 1 4 4 4 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RUS69610.1 - 8e-33 114.0 2.9 3.6e-27 95.4 0.0 3.0 2 1 1 3 3 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RUS69610.1 - 6.1e-30 104.0 3.9 7.2e-30 103.8 1.2 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RUS69610.1 - 1.1e-27 96.9 0.0 8.5e-27 94.0 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RUS69610.1 - 1.1e-19 70.6 0.3 1.5e-16 60.5 0.1 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RUS69610.1 - 2.7e-17 63.1 0.1 1.2e-15 57.7 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RUS69610.1 - 1.9e-12 47.8 0.0 0.00019 21.9 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS69610.1 - 4.2e-11 43.0 0.1 0.0061 16.6 0.0 4.8 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS69610.1 - 1e-09 38.8 0.6 0.025 14.8 0.0 4.8 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 RUS69610.1 - 4.2e-09 37.0 9.3 0.0063 16.9 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 RUS69610.1 - 3.7e-08 34.0 4.4 0.03 14.9 0.0 5.2 5 0 0 5 5 3 2 AAA domain AAA_24 PF13479.6 RUS69610.1 - 8.1e-08 32.2 1.1 1.3 8.7 0.0 5.1 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 RUS69610.1 - 8.1e-08 31.9 0.2 0.08 12.3 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 RUS69610.1 - 2.5e-07 30.8 0.0 1.2e-06 28.6 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 RUS69610.1 - 2.8e-07 30.8 0.1 0.33 11.1 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 RUS69610.1 - 2e-06 27.4 3.0 0.22 11.3 0.0 4.4 4 0 0 4 4 4 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RUS69610.1 - 3e-06 26.8 0.0 0.0093 15.3 0.0 3.0 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.22 RUS69610.1 - 3.3e-06 27.4 0.4 0.26 11.7 0.0 4.3 4 0 0 4 4 3 1 RNA helicase ABC_tran PF00005.27 RUS69610.1 - 5.5e-06 26.9 0.3 0.26 11.8 0.0 4.5 4 0 0 4 4 3 1 ABC transporter AAA_30 PF13604.6 RUS69610.1 - 3.1e-05 23.8 0.2 1.6 8.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 RUS69610.1 - 5.6e-05 23.5 8.1 0.55 10.6 0.0 4.5 5 0 0 5 5 3 2 AAA domain Septin PF00735.18 RUS69610.1 - 8.7e-05 21.9 0.0 0.071 12.4 0.0 2.7 2 0 0 2 2 2 1 Septin Rad17 PF03215.15 RUS69610.1 - 0.00028 20.8 1.6 2.1 8.2 0.1 4.0 4 0 0 4 4 4 2 Rad17 P-loop domain NACHT PF05729.12 RUS69610.1 - 0.00043 20.2 0.4 4.7 7.1 0.0 4.0 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.6 RUS69610.1 - 0.00047 20.2 0.5 0.71 9.9 0.0 4.7 5 0 0 5 5 4 1 AAA domain NTPase_1 PF03266.15 RUS69610.1 - 0.00068 19.6 0.4 0.68 9.8 0.0 4.0 5 0 0 5 5 3 1 NTPase T2SSE PF00437.20 RUS69610.1 - 0.0019 17.3 0.0 1.2 8.2 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein TsaE PF02367.17 RUS69610.1 - 0.002 18.1 0.1 15 5.6 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RUS69610.1 - 0.0022 17.9 0.9 3.2 7.6 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase RuvB_N PF05496.12 RUS69610.1 - 0.0026 17.5 0.1 4.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 RUS69610.1 - 0.0028 17.4 0.0 0.039 13.7 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 RUS69610.1 - 0.0037 16.7 0.1 0.17 11.2 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein cobW PF02492.19 RUS69610.1 - 0.0049 16.5 0.2 5.4 6.6 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 RUS69610.1 - 0.0063 16.3 0.3 1.3 8.7 0.1 3.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 RUS69610.1 - 0.0069 15.7 0.3 3.3 6.9 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.6 RUS69610.1 - 0.015 15.5 4.8 16 5.7 0.0 5.4 5 0 0 5 5 4 0 AAA domain Roc PF08477.13 RUS69610.1 - 0.02 15.1 0.2 3.9 7.7 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS69610.1 - 0.024 14.7 0.5 3.5 7.7 0.0 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase SRPRB PF09439.10 RUS69610.1 - 0.034 13.6 0.9 2.5 7.5 0.0 3.3 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 RUS69610.1 - 0.099 12.2 0.1 26 4.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 RUS69610.1 - 0.12 12.8 32.0 2.7 8.4 1.5 5.7 5 0 0 5 5 5 0 AAA domain DEAD PF00270.29 RUS69610.1 - 0.12 12.1 0.0 23 4.7 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Raptor_N PF14538.6 RUS69610.1 - 0.14 12.1 0.0 0.84 9.6 0.0 2.4 2 0 0 2 2 1 0 Raptor N-terminal CASPase like domain Ras PF00071.22 RUS69611.1 - 1.1e-49 168.1 0.1 1.3e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS69611.1 - 3.4e-29 101.5 0.1 6.5e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS69611.1 - 1.7e-14 53.7 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS69611.1 - 5.9e-06 26.0 0.1 2.4e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 RUS69611.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Gtr1_RagA PF04670.12 RUS69611.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 RUS69611.1 - 0.047 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Radial_spoke_3 PF06098.11 RUS69611.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 HSP70 PF00012.20 RUS69612.1 - 4.2e-179 596.6 5.7 5.2e-179 596.3 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS69612.1 - 1.6e-12 46.9 0.0 2.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 RUS69612.1 - 0.002 17.4 2.8 0.0047 16.2 0.2 2.5 2 1 1 3 3 3 1 StbA protein FGGY_C PF02782.16 RUS69612.1 - 0.0035 17.1 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Seryl_tRNA_N PF02403.22 RUS69612.1 - 0.053 13.7 9.0 2.4 8.4 3.7 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Dzip-like_N PF13815.6 RUS69612.1 - 0.063 13.2 1.7 4.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF2570 PF10828.8 RUS69612.1 - 0.12 12.3 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) HSP70 PF00012.20 RUS69613.1 - 6.8e-39 133.5 0.0 7.8e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 RUS69613.1 - 0.026 14.9 0.0 0.037 14.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA ArenaCapSnatch PF17296.2 RUS69613.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain Ras PF00071.22 RUS69614.1 - 9.8e-42 142.3 0.1 1.9e-41 141.3 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 RUS69614.1 - 7.4e-27 94.0 0.1 1.6e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS69614.1 - 1.7e-09 37.4 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS69614.1 - 3.7e-06 26.4 0.0 5.3e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RUS69614.1 - 0.0075 16.0 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation V-ATPase_C PF03223.15 RUS69615.1 - 1.1e-148 495.6 0.5 1.3e-148 495.4 0.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C MP PF01107.18 RUS69615.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral movement protein (MP) adh_short PF00106.25 RUS69616.1 - 9.9e-40 136.1 0.0 1.3e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS69616.1 - 2.9e-24 85.9 0.0 4.4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS69616.1 - 3.7e-09 36.8 0.0 7.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RUS69616.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zip PF02535.22 RUS69617.1 - 2.8e-65 220.8 20.7 2.1e-64 217.9 20.7 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter TMEM213 PF15192.6 RUS69617.1 - 0.62 10.1 4.4 0.25 11.3 1.3 1.9 2 0 0 2 2 2 0 TMEM213 family DUF4089 PF13318.6 RUS69618.1 - 0.00042 20.7 2.1 1.1e+02 3.3 0.0 5.9 6 1 1 7 7 7 0 Protein of unknown function (DUF4089) RVT_1 PF00078.27 RUS69618.1 - 0.00062 19.3 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4089 PF13318.6 RUS69619.1 - 3.9e-09 36.8 12.8 1.6e+02 2.9 0.0 14.6 19 0 0 19 19 19 0 Protein of unknown function (DUF4089) Colipase-like PF15083.6 RUS69619.1 - 3.2e-05 23.9 28.2 0.024 14.7 1.4 7.4 1 1 7 8 8 8 7 Colipase-like PRP21_like_P PF12230.8 RUS69619.1 - 0.0019 18.1 48.3 6.1 6.6 0.5 10.7 1 1 8 10 10 10 7 Pre-mRNA splicing factor PRP21 like protein zf-U11-48K PF05253.12 RUS69619.1 - 0.11 12.4 20.0 1.5e+02 2.5 0.1 8.1 8 0 0 8 8 8 0 U11-48K-like CHHC zinc finger 7tm_1 PF00001.21 RUS69620.1 - 1.9e-40 138.8 15.1 2.4e-40 138.5 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2208 PF09973.9 RUS69620.1 - 0.0036 17.0 1.7 0.0067 16.1 1.7 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) Synaptobrevin PF00957.21 RUS69620.1 - 2.1 8.2 8.5 13 5.6 3.6 2.6 2 0 0 2 2 2 0 Synaptobrevin Sigma_reg_N PF13800.6 RUS69620.1 - 9.1 6.7 8.3 14 6.1 0.4 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal UPF0086 PF01868.16 RUS69621.1 - 0.035 14.0 0.2 4.8 7.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function UPF0086 BIR PF00653.21 RUS69622.1 - 1.5e-33 115.2 1.2 4e-21 75.5 1.2 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS69622.1 - 2.3e-13 49.8 11.5 2.3e-13 49.8 11.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS69622.1 - 1.4e-05 24.9 11.2 3.9e-05 23.4 11.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS69622.1 - 0.0066 16.8 12.2 0.0066 16.8 12.2 2.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 RUS69622.1 - 0.019 14.9 11.2 0.019 14.9 11.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS69622.1 - 3.5 7.7 14.5 0.092 12.8 4.9 2.7 3 0 0 3 3 3 0 RING-type zinc-finger Gal-3-0_sulfotr PF06990.11 RUS69623.1 - 1.8e-39 135.8 6.1 7.3e-39 133.8 6.1 1.7 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS69623.1 - 4.5e-12 46.4 1.7 9e-12 45.4 1.7 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS69623.1 - 5.8e-05 22.7 1.2 0.00012 21.7 1.2 1.5 1 0 0 1 1 1 1 Sulfotransferase domain PPIP5K2_N PF18086.1 RUS69623.1 - 0.12 12.5 1.4 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain zf-C3HC4_3 PF13920.6 RUS69624.1 - 1.9e-08 34.0 11.6 4.6e-08 32.8 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS69624.1 - 0.00077 19.3 9.8 0.0019 18.0 9.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS69624.1 - 0.038 13.9 12.1 0.11 12.4 12.1 1.9 1 0 0 1 1 1 0 zinc-RING finger domain OrfB_Zn_ribbon PF07282.11 RUS69625.1 - 4.4e-15 55.4 1.1 1.4e-14 53.7 1.1 1.9 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RUS69625.1 - 1.3e-07 31.9 0.5 3.6e-07 30.4 0.5 1.7 1 0 0 1 1 1 1 Probable transposase HypA PF01155.19 RUS69625.1 - 0.027 14.5 0.3 0.056 13.5 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 RUS69625.1 - 0.29 11.5 2.7 0.75 10.2 2.7 1.6 1 0 0 1 1 1 0 C1 domain DNA_RNApol_7kD PF03604.13 RUS69625.1 - 2 8.2 7.6 1.4 8.7 5.3 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.11 RUS69626.1 - 1.1e-18 67.0 0.6 3e-18 65.5 0.6 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 RUS69626.1 - 7.5e-08 32.6 0.8 1.4e-07 31.7 0.8 1.4 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 RUS69626.1 - 0.0046 16.4 0.1 0.011 15.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain C1_2 PF03107.16 RUS69626.1 - 0.046 14.0 0.9 0.11 12.8 0.9 1.6 1 0 0 1 1 1 0 C1 domain TF_Zn_Ribbon PF08271.12 RUS69626.1 - 3.6 7.2 6.2 31 4.2 6.2 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding RNase_H PF00075.24 RUS69627.1 - 8.5e-42 142.7 0.1 3e-41 140.9 0.0 1.8 2 0 0 2 2 2 1 RNase H Thymidylate_kin PF02223.17 RUS69627.1 - 3e-15 56.4 0.1 6.1e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 RUS69627.1 - 9.2e-06 25.7 1.9 3.4e-05 23.8 1.9 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase RVT_3 PF13456.6 RUS69627.1 - 0.00032 20.5 0.0 0.00062 19.6 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase-like AAA_18 PF13238.6 RUS69627.1 - 0.0032 18.0 1.7 0.016 15.8 0.4 2.6 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS69627.1 - 0.015 15.5 0.0 0.058 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RUS69627.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 RUS69627.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family CPT PF07931.12 RUS69627.1 - 0.047 13.5 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TipAS PF07739.13 RUS69627.1 - 0.8 10.3 3.4 0.37 11.3 0.2 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Ank_3 PF13606.6 RUS69628.1 - 1.1e-25 86.8 2.1 5.1e-06 26.4 0.1 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 RUS69628.1 - 8.1e-23 80.8 6.4 8.4e-11 42.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69628.1 - 3.6e-22 78.4 7.8 1.3e-08 35.2 0.4 4.4 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS69628.1 - 5.2e-22 77.3 5.3 2.4e-05 24.6 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS69628.1 - 3.6e-17 62.2 7.8 1.5e-07 31.6 1.0 4.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Nucleos_tra2_C PF07662.13 RUS69629.1 - 2.6e-65 220.1 4.9 2.6e-65 220.1 4.9 2.9 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS69629.1 - 4.1e-18 65.7 6.0 4.1e-18 65.7 6.0 3.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS69629.1 - 0.0014 18.9 10.5 0.0014 18.9 10.5 3.4 3 1 0 3 3 3 1 Nucleoside recognition Orf78 PF06024.12 RUS69629.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.7 5 0 0 5 5 5 0 Orf78 (ac78) Prok-RING_4 PF14447.6 RUS69630.1 - 0.0022 17.8 17.1 0.0055 16.5 14.1 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Snapin_Pallidin PF14712.6 RUS69630.1 - 0.068 13.6 2.4 0.17 12.4 1.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Prp19 PF08606.11 RUS69630.1 - 0.087 12.8 0.5 0.37 10.8 0.5 2.1 1 0 0 1 1 1 0 Prp19/Pso4-like DUF5318 PF17249.2 RUS69630.1 - 0.095 12.5 3.3 0.3 10.9 2.9 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5318) DUF913 PF06025.12 RUS69630.1 - 0.2 10.6 11.7 1.7 7.5 1.6 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Epimerase PF01370.21 RUS69631.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS69631.1 - 0.0056 15.7 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ten1_2 PF15490.6 RUS69632.1 - 6.4e-17 61.4 0.0 3e-16 59.2 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 RUS69632.1 - 2.8e-05 24.4 0.1 0.00073 19.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor A protein 3 DPPIV_N PF00930.21 RUS69633.1 - 4.3e-66 223.1 0.0 2.1e-64 217.5 0.0 2.2 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 RUS69633.1 - 1.6e-54 184.6 0.0 2.6e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RUS69633.1 - 1.3e-12 47.9 0.1 3.2e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 RUS69633.1 - 0.0001 21.7 0.4 0.0087 15.3 0.1 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS69633.1 - 0.00013 22.7 0.0 0.00029 21.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 RUS69633.1 - 0.00018 21.3 0.2 0.00057 19.6 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 RUS69633.1 - 0.0058 16.5 0.7 2.4 7.9 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 RUS69633.1 - 0.0089 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 RUS69633.1 - 0.076 11.7 0.1 0.38 9.4 0.1 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 RUS69633.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 RUS69633.1 - 0.18 11.3 0.0 0.89 9.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family PDZ PF00595.24 RUS69634.1 - 1.7e-19 70.0 2.5 1.3e-11 44.7 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RUS69634.1 - 3e-14 52.6 0.1 6e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS69634.1 - 5.5e-12 45.8 0.4 7e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 PDZ domain zf-CDGSH PF09360.10 RUS69635.1 - 7.8e-10 38.8 0.1 1.3e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Pentapeptide PF00805.22 RUS69636.1 - 2.6e-07 30.1 17.5 0.0065 16.1 0.9 4.2 1 1 6 7 7 7 7 Pentapeptide repeats (8 copies) zf-CDGSH PF09360.10 RUS69637.1 - 2.4e-11 43.6 0.1 3.8e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type PfkB PF00294.24 RUS69638.1 - 7.2e-75 252.1 0.1 8.4e-75 251.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Metallophos PF00149.28 RUS69639.1 - 4.1e-12 47.0 0.0 6.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F5_F8_type_C PF00754.25 RUS69640.1 - 6.9e-08 32.7 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain LisH PF08513.11 RUS69641.1 - 3.6e-09 36.2 0.3 7.5e-09 35.2 0.1 1.6 2 0 0 2 2 2 1 LisH Lectin_C PF00059.21 RUS69642.1 - 2.2e-13 50.9 0.2 4e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain OAD_gamma PF04277.13 RUS69642.1 - 0.031 14.9 0.0 0.053 14.1 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RVT_1 PF00078.27 RUS69643.1 - 2.4e-05 23.9 0.1 3.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 RUS69644.1 - 7e-05 23.1 37.0 0.019 15.4 2.4 5.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS69644.1 - 0.00058 19.6 3.2 0.00058 19.6 3.2 3.8 4 1 0 4 4 4 1 C2H2-type zinc-finger domain CDC24_OB3 PF17244.2 RUS69644.1 - 0.018 14.8 8.4 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 3 OrsD PF12013.8 RUS69644.1 - 0.031 14.7 10.1 2.4 8.6 0.6 4.1 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met PF12874.7 RUS69644.1 - 0.069 13.6 1.1 0.069 13.6 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 RUS69644.1 - 4.3 7.6 17.7 1e+02 3.2 1.9 4.6 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 RUS69644.1 - 4.4 7.9 26.6 0.34 11.4 0.3 6.3 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS69644.1 - 7.8 7.6 32.5 0.076 13.9 2.0 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS69644.1 - 9.9 6.6 18.0 0.38 11.1 0.2 3.6 4 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF5564 PF17719.1 RUS69646.1 - 2.8e-06 27.4 9.2 2.8e-06 27.4 9.2 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5564) DUF4551 PF15087.6 RUS69646.1 - 1.2 7.9 10.3 1.4 7.7 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 RUS69646.1 - 5.7 5.7 11.3 7 5.4 11.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pox_VLTF3 PF04947.14 RUS69647.1 - 0.0065 16.2 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like Lectin_C PF00059.21 RUS69648.1 - 1.3e-15 58.0 0.4 2.9e-15 56.9 0.4 1.6 1 0 0 1 1 1 1 Lectin C-type domain DEFB136 PF17333.2 RUS69648.1 - 0.00057 19.8 7.1 0.011 15.7 1.7 2.7 2 0 0 2 2 2 2 Beta defensin 136 Trypsin_2 PF13365.6 RUS69649.1 - 9.9e-05 23.3 0.0 0.00025 22.0 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain ARD PF03079.14 RUS69650.1 - 6.7e-35 120.6 0.3 8.1e-35 120.3 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS69650.1 - 3.7e-08 33.0 0.0 5.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS69650.1 - 0.0022 17.9 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Phage_term_smal PF05944.12 RUS69650.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Phage small terminase subunit Peptidase_M76 PF09768.9 RUS69650.1 - 0.021 14.6 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family EP400_N PF15790.5 RUS69650.1 - 0.024 13.5 0.0 0.03 13.2 0.0 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal ARD PF03079.14 RUS69651.1 - 3e-26 92.5 0.0 3.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS69651.1 - 2.3e-11 43.2 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS69651.1 - 5.3e-05 23.1 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 RUS69651.1 - 0.00013 21.6 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 RUS69651.1 - 0.0018 18.0 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RUS69651.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase MannoseP_isomer PF01050.18 RUS69651.1 - 0.037 13.9 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DUF1287 PF06940.11 RUS69651.1 - 0.038 13.7 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1287) Cupin_4 PF08007.12 RUS69651.1 - 0.18 11.2 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein ARD PF03079.14 RUS69652.1 - 9.7e-22 77.8 0.0 1.2e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS69652.1 - 4.9e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 RUS69652.1 - 0.056 13.9 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase DNA_ligase_A_M PF01068.21 RUS69652.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Cupin_8 PF13621.6 RUS69652.1 - 0.13 12.0 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain TLP-20 PF06088.11 RUS69654.1 - 0.037 13.9 0.2 0.06 13.2 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.11 RUS69654.1 - 0.12 11.9 10.6 0.11 12.1 8.2 1.8 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 RUS69654.1 - 0.32 10.3 11.1 0.47 9.7 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 RUS69654.1 - 0.56 10.0 9.6 0.79 9.5 9.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 RUS69654.1 - 0.78 9.4 9.7 1.3 8.7 9.7 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RUS69654.1 - 2.8 6.1 11.6 3.8 5.7 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RUS69654.1 - 6.6 5.9 8.5 9 5.4 8.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 RUS69654.1 - 7.5 5.9 15.4 9.4 5.6 15.4 1.1 1 0 0 1 1 1 0 SDA1 Mucin-like PF16058.5 RUS69656.1 - 0.00039 20.4 0.4 0.29 11.2 0.1 2.4 2 0 0 2 2 2 2 Mucin-like LEA_4 PF02987.16 RUS69656.1 - 0.0015 18.6 0.3 4.9 7.3 0.1 4.1 2 1 0 3 3 3 2 Late embryogenesis abundant protein Fumarate_red_C PF02300.17 RUS69656.1 - 0.065 13.3 18.0 57 3.8 0.1 7.8 4 2 4 8 8 8 0 Fumarate reductase subunit C DUF1367 PF07105.11 RUS69656.1 - 0.33 10.6 7.4 0.68 9.6 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1367) Copper-fist PF00649.18 RUS69657.1 - 0.0087 15.5 0.5 0.0087 15.5 0.5 3.1 3 0 0 3 3 3 1 Copper fist DNA binding domain CUB PF00431.20 RUS69659.1 - 1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain DUF1010 PF06231.11 RUS69660.1 - 0.0023 18.4 17.2 29 5.3 0.3 5.6 1 1 8 9 9 9 8 Protein of unknown function (DUF1010) DUF685 PF05085.12 RUS69660.1 - 1.2 8.4 6.0 10 5.4 0.2 3.6 1 1 5 6 6 6 0 Protein of unknown function (DUF685) PALP PF00291.25 RUS69661.1 - 5e-32 111.5 1.4 3.5e-27 95.6 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme GST_N_3 PF13417.6 RUS69662.1 - 2.6e-11 43.8 0.1 3.8e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS69662.1 - 1.5e-08 34.8 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS69662.1 - 2e-07 31.2 0.0 3.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 RUS69662.1 - 6.5e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GCV_H PF01597.19 RUS69663.1 - 2.6e-38 130.7 0.1 2.8e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Asparaginase_2 PF01112.18 RUS69664.1 - 2e-60 204.4 7.7 1.1e-59 201.9 7.7 1.8 1 1 0 1 1 1 1 Asparaginase DUF1024 PF06260.12 RUS69664.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Ribul_P_3_epim PF00834.19 RUS69665.1 - 4e-78 261.3 0.3 4.6e-78 261.2 0.3 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 RUS69665.1 - 5.9e-06 26.2 0.2 0.00026 20.8 0.0 2.4 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Trp_syntA PF00290.20 RUS69665.1 - 0.00013 20.9 0.0 0.00019 20.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain CutC PF03932.14 RUS69665.1 - 0.0017 17.9 0.2 0.19 11.1 0.0 2.1 2 0 0 2 2 2 2 CutC family KDGP_aldolase PF07071.11 RUS69665.1 - 0.004 17.0 0.6 1.3 8.7 0.0 2.4 3 0 0 3 3 3 2 KDGP aldolase His_biosynth PF00977.21 RUS69665.1 - 0.0051 16.3 0.1 0.073 12.5 0.0 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein SAM_4 PF18017.1 RUS69665.1 - 0.011 15.6 0.2 1.9 8.5 0.0 3.0 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) IGPS PF00218.21 RUS69665.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Lactamase_B PF00753.27 RUS69666.1 - 7.1e-17 62.1 4.7 2.6e-16 60.2 4.7 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 RUS69666.1 - 1.7e-08 34.8 0.1 2.9e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 RUS69666.1 - 1e-06 28.4 0.2 6.6e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS69666.1 - 0.009 15.9 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain tRNA-synt_2b PF00587.25 RUS69667.1 - 8.8e-44 149.6 0.0 1.4e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RUS69667.1 - 4.8e-12 45.9 0.0 8.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CN_hydrolase PF00795.22 RUS69668.1 - 2.1e-13 50.2 0.0 2.6e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 RUS69670.1 - 5.3e-49 167.3 0.2 5.9e-49 167.2 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RUS69670.1 - 6e-07 28.3 0.4 8e-07 27.9 0.4 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RUS69670.1 - 7.1e-06 25.2 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RUS69670.1 - 0.0055 16.0 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_C5 PF00770.18 RUS69670.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease DegT_DnrJ_EryC1 PF01041.17 RUS69670.1 - 0.093 12.0 0.6 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CN_hydrolase PF00795.22 RUS69671.1 - 1.7e-30 106.2 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase dCache_1 PF02743.18 RUS69671.1 - 0.026 14.3 0.9 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Cache domain Pyr_redox_2 PF07992.14 RUS69672.1 - 5.1e-59 199.9 0.1 5.8e-59 199.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS69672.1 - 4.2e-20 72.1 5.2 1.3e-18 67.3 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS69672.1 - 3.6e-14 52.7 0.0 1.2e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS69672.1 - 1.2e-10 41.5 0.0 0.00033 20.8 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS69672.1 - 3.4e-10 40.0 0.9 0.002 17.8 0.1 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 RUS69672.1 - 1.7e-06 27.4 0.0 2.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 RUS69672.1 - 1.9e-05 23.6 1.6 0.057 12.1 0.1 3.6 3 1 1 4 4 4 2 HI0933-like protein 3HCDH_N PF02737.18 RUS69672.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RUS69672.1 - 0.00015 21.4 0.2 0.00037 20.1 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 RUS69672.1 - 0.00034 20.6 0.7 1.6 8.7 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RUS69672.1 - 0.00036 19.7 0.0 0.0042 16.2 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 RUS69672.1 - 0.0072 16.7 0.1 0.22 12.0 0.0 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 RUS69672.1 - 0.0096 16.2 1.3 0.037 14.3 0.2 2.5 2 1 1 3 3 3 1 TrkA-N domain DUF1188 PF06690.11 RUS69672.1 - 0.011 15.4 0.1 0.063 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 RUS69672.1 - 0.011 15.0 0.1 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 RUS69672.1 - 0.021 14.4 0.0 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 RUS69672.1 - 0.024 14.8 0.1 0.058 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 RUS69672.1 - 0.026 13.8 0.2 2.6 7.2 0.0 2.4 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 RUS69672.1 - 0.031 14.3 0.1 0.085 12.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 RUS69672.1 - 0.043 13.1 2.0 0.21 10.8 0.0 2.6 4 0 0 4 4 4 0 FAD binding domain 2-Hacid_dh_C PF02826.19 RUS69672.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 RUS69672.1 - 0.081 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FAD_binding_2 PF00890.24 RUS69672.1 - 0.11 11.5 0.3 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Transketolase_C PF02780.20 RUS69672.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Transketolase, C-terminal domain HAP1_N PF04849.13 RUS69674.1 - 4.4e-87 292.2 36.6 4.6e-77 259.2 33.1 2.5 1 1 1 2 2 2 2 HAP1 N-terminal conserved region Milton PF12448.8 RUS69674.1 - 1.1e-16 61.4 8.4 1.1e-16 61.4 8.4 5.1 3 2 2 5 5 5 1 Kinesin associated protein KASH_CCD PF14662.6 RUS69674.1 - 0.53 10.1 34.2 0.33 10.7 20.8 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 RUS69674.1 - 2.1 8.9 30.6 11 6.5 3.8 4.6 2 1 1 3 3 3 0 Cell division protein ZapB SHE3 PF17078.5 RUS69674.1 - 7.7 6.2 25.2 1.4 8.5 16.1 2.9 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 RUS69674.1 - 9.2 6.5 18.5 9.1 6.5 3.3 3.9 3 0 0 3 3 3 0 bZIP transcription factor Peptidase_C14 PF00656.22 RUS69675.1 - 0.00066 19.7 0.0 0.00073 19.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF1082 PF06449.11 RUS69676.1 - 0.09 12.6 0.1 0.21 11.5 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) DUF5575 PF17738.1 RUS69677.1 - 0.0022 17.1 0.1 0.003 16.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) FAR1 PF03101.15 RUS69677.1 - 0.0023 18.6 0.5 0.0055 17.4 0.5 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Crust_neurohorm PF01147.17 RUS69677.1 - 0.38 10.6 2.8 41 4.1 0.1 3.3 2 1 1 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family BCDHK_Adom3 PF10436.9 RUS69678.1 - 1.4e-38 132.3 0.1 2.6e-38 131.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RUS69678.1 - 4.7e-12 46.4 0.1 3.3e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PP2C PF00481.21 RUS69680.1 - 4.3e-54 183.8 0.0 4.9e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS69680.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Telomerase_RBD PF12009.8 RUS69681.1 - 7e-19 68.3 4.7 7e-19 68.3 4.7 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 RUS69681.1 - 1.6e-10 40.9 4.1 2.6e-06 27.1 0.1 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_12 PF07740.12 RUS69682.1 - 0.033 14.9 3.8 0.033 14.9 3.8 3.7 3 0 0 3 3 3 0 Ion channel inhibitory toxin UPF0506 PF11703.8 RUS69682.1 - 2 8.8 22.4 2.6 8.5 10.6 3.3 2 1 1 3 3 3 0 UPF0506 Toxin_35 PF10530.9 RUS69682.1 - 2.2 8.3 19.4 9 6.4 3.1 3.3 3 0 0 3 3 3 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_35 PF10530.9 RUS69683.1 - 3.2e-05 23.8 28.3 0.1 12.6 4.2 3.2 3 0 0 3 3 3 3 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_12 PF07740.12 RUS69683.1 - 0.0002 22.0 41.4 0.12 13.1 9.3 3.3 3 0 0 3 3 3 3 Ion channel inhibitory toxin UPF0506 PF11703.8 RUS69683.1 - 0.022 15.1 40.8 1 9.8 8.4 3.1 3 0 0 3 3 3 0 UPF0506 Lustrin_cystein PF14625.6 RUS69683.1 - 0.16 12.4 26.6 2.8 8.4 3.7 3.5 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 RUS69683.1 - 0.25 11.9 34.2 2.4 8.7 5.6 3.3 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Peptidase_M13 PF01431.21 RUS69683.1 - 0.3 10.7 1.2 65 3.0 0.0 3.0 3 0 0 3 3 3 0 Peptidase family M13 Toxin_7 PF05980.12 RUS69683.1 - 0.63 10.3 40.8 0.75 10.1 7.7 3.3 3 0 0 3 3 3 0 Toxin 7 Toxin_24 PF08094.11 RUS69683.1 - 3 7.7 34.0 3.6 7.5 7.0 3.5 3 0 0 3 3 3 0 Conotoxin TVIIA/GS family Tachystatin_A PF11406.8 RUS69683.1 - 4.1 7.6 16.0 17 5.6 0.3 3.6 3 0 0 3 3 3 0 Antimicrobial peptide tachystatin A SPRR2 PF14820.6 RUS69683.1 - 7.2 6.8 15.7 8.6 6.5 0.8 3.1 3 0 0 3 3 3 0 Small proline-rich 2 Pkinase PF00069.25 RUS69686.1 - 3.8e-28 98.6 0.0 1.3e-17 64.0 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69686.1 - 3.6e-20 72.3 0.0 6.8e-15 55.1 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 RUS69686.1 - 6.2e-08 32.2 0.0 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS69686.1 - 0.00099 19.1 1.6 2.1 8.2 0.4 3.6 2 2 0 3 3 3 2 Phosphotransferase enzyme family Sugar_tr PF00083.24 RUS69687.1 - 9.2e-26 90.7 27.0 1.3e-25 90.2 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS69687.1 - 1.6e-16 60.2 48.1 1.4e-11 43.9 21.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF285 PF03382.14 RUS69688.1 - 0.0027 17.4 0.5 0.047 13.4 0.6 2.3 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 BLOC1_2 PF10046.9 RUS69688.1 - 0.003 17.8 2.8 0.42 10.9 0.2 2.9 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 KIF1B PF12423.8 RUS69688.1 - 0.0045 17.4 32.3 50 4.4 0.1 11.0 10 2 1 11 11 11 0 Kinesin protein 1B RcsD_ABL PF16359.5 RUS69688.1 - 0.0084 16.2 2.3 20 5.4 0.0 3.4 1 1 2 4 4 4 0 RcsD-ABL domain HAMP_N3 PF18575.1 RUS69688.1 - 0.091 12.3 0.0 1.7e+02 1.9 0.0 4.0 4 0 0 4 4 4 0 HAMP N-terminal domain 3 Gas_vesicle_C PF01304.17 RUS69688.1 - 0.13 12.3 25.4 38 4.4 0.0 9.0 10 0 0 10 10 10 0 Gas vesicles protein GVPc repeated domain Cor1 PF04803.12 RUS69688.1 - 0.81 9.9 14.1 10 6.4 3.6 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region IZUMO PF15005.6 RUS69688.1 - 1.9 9.0 7.6 13 6.3 1.3 2.8 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated BEX PF04538.12 RUS69688.1 - 5 7.7 8.1 5.4 7.6 0.5 3.1 1 1 1 3 3 3 0 Brain expressed X-linked like family AAA_16 PF13191.6 RUS69688.1 - 9.8 6.5 15.5 5.3 7.4 2.8 2.5 1 1 1 2 2 2 0 AAA ATPase domain Coa1 PF08695.10 RUS69690.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 SNN_transmemb PF09049.10 RUS69692.1 - 0.27 11.2 1.8 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Stannin transmembrane Glyco_transf_41 PF13844.6 RUS69693.1 - 5.2e-247 819.8 0.0 7.2e-247 819.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 RUS69693.1 - 6.8e-91 294.7 34.2 7.9e-09 35.0 0.2 13.5 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_11 PF13414.6 RUS69693.1 - 1.5e-89 293.4 37.2 7.9e-12 44.7 0.9 12.9 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 RUS69693.1 - 9.3e-69 222.1 30.0 4.4e-07 29.5 0.1 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 RUS69693.1 - 3.4e-64 208.7 36.8 2.1e-08 34.0 0.2 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_8 PF13181.6 RUS69693.1 - 2.3e-61 198.9 18.5 1.4e-06 28.0 0.0 13.3 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 RUS69693.1 - 2.7e-46 155.8 30.9 3.9e-11 43.1 0.7 9.4 5 2 5 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 RUS69693.1 - 5.5e-41 135.7 14.9 0.00013 22.5 0.0 12.6 5 3 7 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 RUS69693.1 - 6.6e-40 135.5 11.4 2.2e-07 31.4 0.0 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 RUS69693.1 - 1.2e-36 122.0 19.3 8.4e-05 22.3 0.0 13.1 13 1 1 14 14 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 RUS69693.1 - 4.4e-35 120.0 23.6 3.8e-07 30.5 0.4 8.9 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 RUS69693.1 - 1.9e-34 116.6 49.1 1e-06 28.4 0.5 13.4 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_9 PF13371.6 RUS69693.1 - 8.4e-16 57.9 10.0 0.0069 16.5 0.0 6.6 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 RUS69693.1 - 1.3e-12 47.5 16.1 0.51 11.1 0.0 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat NARP1 PF12569.8 RUS69693.1 - 2.8e-12 46.4 6.5 0.012 14.6 0.0 5.6 1 1 4 6 6 6 4 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 RUS69693.1 - 8.2e-12 45.1 11.6 0.00042 19.8 0.4 4.2 2 2 1 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 RUS69693.1 - 2.2e-11 43.2 6.2 1.6 9.6 0.1 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat FAT PF02259.23 RUS69693.1 - 5.2e-08 32.5 0.3 0.11 11.7 0.3 5.9 2 2 2 4 4 4 1 FAT domain TPR_15 PF13429.6 RUS69693.1 - 2.5e-07 30.2 12.6 0.00069 18.9 0.3 5.5 2 2 2 4 4 4 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 RUS69693.1 - 3e-06 27.0 13.8 0.13 11.7 0.2 5.6 4 1 2 6 6 6 3 Est1 DNA/RNA binding domain Wzy_C_2 PF11846.8 RUS69693.1 - 0.00014 21.9 11.7 0.074 13.0 0.3 4.9 4 1 2 6 6 6 1 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 RUS69693.1 - 0.00017 21.4 10.7 0.34 10.6 0.3 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 RUS69693.1 - 0.0011 19.1 7.2 0.011 15.9 1.5 5.3 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 RUS69693.1 - 0.0012 18.3 17.3 0.081 12.3 3.5 4.8 2 2 2 5 5 5 2 Soluble NSF attachment protein, SNAP BTAD PF03704.17 RUS69693.1 - 0.0013 19.2 11.8 2.5 8.5 0.5 4.6 2 2 1 3 3 3 2 Bacterial transcriptional activator domain TPR_3 PF07720.12 RUS69693.1 - 0.0027 17.6 5.2 0.7 10.0 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat MIT PF04212.18 RUS69693.1 - 0.0035 17.4 27.6 8.5 6.5 0.1 8.8 9 0 0 9 9 8 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 RUS69693.1 - 0.021 15.2 13.0 0.3 11.4 0.3 5.7 3 1 3 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 RUS69693.1 - 0.031 14.5 3.5 24 5.5 0.0 6.3 7 0 0 7 7 6 0 PPR repeat Fis1_TPR_C PF14853.6 RUS69693.1 - 0.039 14.0 0.2 0.32 11.1 0.1 2.8 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 RUS69693.1 - 0.043 13.2 1.7 4.6 6.6 0.3 3.4 2 1 0 3 3 3 0 Coatomer epsilon subunit DUF627 PF04781.12 RUS69693.1 - 0.15 12.1 4.8 14 5.8 0.0 4.9 2 1 2 4 4 4 0 Protein of unknown function (DUF627) Nitrophorin PF02087.15 RUS69693.1 - 0.16 12.0 0.1 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Nitrophorin Mad3_BUB1_I PF08311.12 RUS69693.1 - 0.22 11.5 10.9 18 5.4 0.0 6.3 6 1 0 7 7 7 0 Mad3/BUB1 homology region 1 SHNi-TPR PF10516.9 RUS69693.1 - 0.24 10.9 9.4 9 5.9 0.0 5.8 7 1 1 8 8 7 0 SHNi-TPR USP8_dimer PF08969.11 RUS69693.1 - 0.27 11.4 0.9 2.5 8.3 0.2 2.8 2 0 0 2 2 2 0 USP8 dimerisation domain Glyco_transf_10 PF00852.19 RUS69696.1 - 4e-48 163.5 0.1 6.6e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Mpp10 PF04006.12 RUS69696.1 - 0.063 11.7 16.4 0.082 11.3 16.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS69696.1 - 0.23 9.6 29.6 0.3 9.2 29.6 1.0 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.9 RUS69696.1 - 1.4 7.8 6.8 1.9 7.4 6.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DNA_pol_phi PF04931.13 RUS69696.1 - 3.1 5.8 51.1 4.1 5.4 51.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RUS69696.1 - 5 6.4 25.2 6.4 6.0 25.2 1.1 1 0 0 1 1 1 0 BUD22 zf-Sec23_Sec24 PF04810.15 RUS69697.1 - 0.0018 18.3 4.7 36 4.5 0.0 5.4 1 1 5 7 7 7 4 Sec23/Sec24 zinc finger SbsC_C PF18058.1 RUS69697.1 - 2.3 8.4 14.9 7.8 6.7 1.8 3.2 1 1 3 4 4 4 0 SbsC C-terminal domain MDM1 PF15501.6 RUS69699.1 - 2.9e-66 224.8 9.1 4.7e-66 224.1 9.1 1.3 1 0 0 1 1 1 1 Nuclear protein MDM1 PBP1_TM PF14812.6 RUS69699.1 - 6.6 7.2 16.0 8.4 6.8 8.8 3.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tetraspanin PF00335.20 RUS69700.1 - 9e-09 35.4 2.7 1.2e-08 34.9 2.7 1.2 1 0 0 1 1 1 1 Tetraspanin family LRR_9 PF14580.6 RUS69701.1 - 2.1e-28 99.0 10.6 1.8e-16 60.2 1.9 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 RUS69701.1 - 1.7e-18 66.4 42.4 1.6e-06 28.4 3.2 6.5 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS69701.1 - 3e-13 49.3 26.0 2e-06 27.4 2.9 5.9 4 1 3 7 7 7 5 Leucine rich repeat DBC1 PF14443.6 RUS69701.1 - 0.086 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 DBC1 dsrm PF00035.26 RUS69702.1 - 1.3e-38 131.5 2.5 5.5e-16 59.0 0.1 3.3 3 0 0 3 3 3 3 Double-stranded RNA binding motif Staufen_C PF16482.5 RUS69702.1 - 1.6e-12 47.6 2.6 5.3e-10 39.4 0.4 3.6 3 1 0 3 3 3 1 Staufen C-terminal domain DND1_DSRM PF14709.7 RUS69702.1 - 3.9e-08 33.4 7.6 0.0029 17.8 0.7 4.8 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.16 RUS69702.1 - 0.69 10.3 12.2 0.25 11.7 1.5 3.1 3 1 0 3 3 3 0 LPP20 lipoprotein GAGA_bind PF06217.12 RUS69702.1 - 0.81 9.9 6.2 2.3 8.5 6.1 1.7 1 1 1 2 2 2 0 GAGA binding protein-like family NIBRIN_BRCT_II PF16508.5 RUS69702.1 - 1.1 9.6 3.8 2.8 8.3 1.5 2.5 2 1 1 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein HEAT_PBS PF03130.16 RUS69703.1 - 5.9e-12 45.1 0.0 5.6e+02 1.7 0.0 12.5 14 0 0 14 14 14 0 PBS lyase HEAT-like repeat Vps54 PF07928.12 RUS69703.1 - 0.097 13.1 4.8 36 4.8 0.0 5.4 1 1 4 5 5 5 0 Vps54-like protein Drc1-Sld2 PF11719.8 RUS69703.1 - 1.9 7.9 11.9 2.5 7.6 11.9 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein YjeF_N PF03853.15 RUS69706.1 - 3.5e-10 40.0 0.0 3.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 RUS69706.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DEC-1_N PF04625.13 RUS69706.1 - 1.3 8.0 3.5 1.2 8.0 3.5 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.11 RUS69706.1 - 2 8.4 5.7 2.6 8.0 5.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator AMP-binding PF00501.28 RUS69707.1 - 1.4e-39 135.9 0.0 1.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS69707.1 - 0.0011 20.0 0.0 0.0023 18.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RUS69708.1 - 1.9e-46 158.5 0.0 2.2e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Keratin_2_head PF16208.5 RUS69709.1 - 8.4 6.5 12.1 13 5.9 12.1 1.4 1 1 0 1 1 1 0 Keratin type II head Glyco_transf_10 PF00852.19 RUS69710.1 - 2.9e-23 82.5 0.0 5.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS69710.1 - 2.3e-15 57.0 0.6 5.5e-15 55.8 0.3 1.8 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Ferric_reduct PF01794.19 RUS69711.1 - 2.4e-14 53.5 7.7 5.6e-07 29.7 0.3 2.3 2 0 0 2 2 2 2 Ferric reductase like transmembrane component Cornifin PF02389.15 RUS69711.1 - 0.00013 22.1 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family EF-hand_6 PF13405.6 RUS69711.1 - 0.00084 19.1 5.1 0.51 10.4 0.6 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RUS69711.1 - 0.0019 17.6 12.0 0.0022 17.4 1.6 3.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 RUS69711.1 - 0.013 16.0 3.4 0.1 13.0 0.1 3.1 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS69711.1 - 0.058 12.9 6.0 1.2 8.8 0.4 2.9 3 0 0 3 3 3 0 EF hand Sarcolipin PF05366.11 RUS69711.1 - 1.2 8.9 4.7 44 3.9 0.1 3.4 3 0 0 3 3 3 0 Sarcolipin Ripply PF14998.6 RUS69714.1 - 0.00012 22.6 8.9 0.62 10.7 0.5 4.1 1 1 2 3 3 3 3 Transcription Regulator Rcd1 PF04078.13 RUS69714.1 - 0.086 12.1 2.6 5.6 6.2 1.0 2.9 1 1 1 2 2 2 0 Cell differentiation family, Rcd1-like DUF5594 PF18057.1 RUS69714.1 - 0.8 9.6 2.8 27 4.6 0.2 2.9 1 1 0 3 3 3 0 Domain of unknown function (DUF5594) LRRCT PF01463.24 RUS69714.1 - 7.8 7.3 8.9 21 6.0 0.5 3.8 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain 7tm_1 PF00001.21 RUS69716.1 - 6.7e-16 58.4 14.0 8.8e-16 58.0 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS69716.1 - 1.3e-15 57.5 14.9 2.5e-15 56.6 14.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4149 PF13664.6 RUS69716.1 - 0.00083 19.6 0.5 0.003 17.8 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2254 PF10011.9 RUS69716.1 - 0.011 14.6 0.7 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Vma12 PF11712.8 RUS69716.1 - 0.092 12.8 0.9 0.29 11.2 0.2 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF485 PF04341.12 RUS69716.1 - 0.25 11.3 0.0 0.25 11.3 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function, DUF485 DUF3566 PF12089.8 RUS69716.1 - 0.77 10.1 8.2 0.13 12.6 0.8 3.0 2 1 1 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Lactamase_B_2 PF12706.7 RUS69717.1 - 2e-24 86.3 0.2 2.4e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain C1_2 PF03107.16 RUS69718.1 - 7e-19 67.9 52.7 0.0071 16.6 1.5 7.1 1 1 10 11 11 11 11 C1 domain Zf_RING PF16744.5 RUS69718.1 - 7.2e-09 35.6 39.1 0.85 9.8 0.6 7.0 1 1 9 10 10 10 10 KIAA1045 RING finger Gamma-thionin PF00304.20 RUS69718.1 - 0.00033 20.8 49.5 31 4.9 0.4 12.0 1 1 12 13 13 13 0 Gamma-thionin family zf_C2H2_6 PF18450.1 RUS69718.1 - 0.0024 17.5 44.1 67 3.3 0.2 12.6 1 1 12 13 13 13 0 Zinc Finger domain Rubredoxin_2 PF18073.1 RUS69718.1 - 0.059 13.1 42.5 22 4.9 0.9 10.3 1 1 11 12 12 12 0 Rubredoxin metal binding domain SAM_2 PF07647.17 RUS69718.1 - 0.075 13.2 39.5 78 3.5 0.7 11.7 1 1 12 13 13 13 0 SAM domain (Sterile alpha motif) Herpes_BLLF1 PF05109.13 RUS69719.1 - 0.044 11.8 27.1 0.91 7.4 12.5 2.2 1 1 1 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF1249 PF06853.12 RUS69720.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1249) Cdd1 PF11731.8 RUS69721.1 - 0.017 15.3 0.0 34 4.8 0.0 3.5 1 1 3 4 4 4 0 Pathogenicity locus SPC22 PF04573.12 RUS69721.1 - 0.8 9.2 4.3 43 3.5 0.1 4.0 1 1 4 5 5 5 0 Signal peptidase subunit Ribosomal_S5_C PF03719.15 RUS69721.1 - 6.6 6.3 11.3 25 4.4 0.2 3.6 1 1 3 4 4 4 0 Ribosomal protein S5, C-terminal domain PAM2 PF07145.15 RUS69722.1 - 0.00044 19.7 5.2 0.0023 17.5 0.9 5.7 7 0 0 7 7 7 4 Ataxin-2 C-terminal region PAM2 PF07145.15 RUS69723.1 - 3.2e-05 23.3 11.2 0.016 14.9 0.1 3.7 5 0 0 5 5 5 2 Ataxin-2 C-terminal region W_rich_C PF07483.11 RUS69723.1 - 0.047 13.8 0.4 70 3.6 0.0 3.5 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain DUF2559 PF10832.8 RUS69723.1 - 0.15 12.1 0.3 31 4.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) LURAP PF14854.6 RUS69724.1 - 4.3e-05 23.4 0.2 4.3e-05 23.4 0.2 2.1 2 1 1 3 3 3 1 Leucine rich adaptor protein Baculo_11_kDa PF06143.11 RUS69725.1 - 0.013 15.1 10.4 0.24 11.0 0.4 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF4834 PF16118.5 RUS69725.1 - 7.1 7.7 8.1 36 5.4 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Renin_r PF07850.14 RUS69725.1 - 7.7 7.2 8.2 28 5.4 0.6 3.3 3 0 0 3 3 3 0 Renin receptor-like protein Toxin_21 PF08091.11 RUS69727.1 - 0.16 11.9 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Spider insecticidal peptide CDC45 PF02724.14 RUS69729.1 - 5.3 5.2 7.4 6.9 4.8 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 RUS69729.1 - 9.9 4.6 8.2 12 4.2 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_1 PF00078.27 RUS69732.1 - 2.9e-23 82.6 0.0 4.9e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MLVIN_C PF18697.1 RUS69733.1 - 0.028 14.5 0.0 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ATG11 PF10377.9 RUS69733.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 EF-hand_7 PF13499.6 RUS69734.1 - 1.8e-07 31.5 0.6 1.1e-06 28.9 0.7 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS69734.1 - 4e-06 26.3 0.3 0.12 12.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RUS69734.1 - 7.9e-05 21.9 0.5 0.071 12.7 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS69734.1 - 0.007 16.2 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS69734.1 - 0.05 13.1 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 RUS69734.1 - 0.076 13.4 0.1 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Tau95 PF09734.9 RUS69735.1 - 1.6 9.6 4.9 7.6 7.3 0.0 3.3 2 1 1 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Eapp_C PF10238.9 RUS69736.1 - 0.0013 18.8 4.8 0.0018 18.4 4.8 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein DDHD PF02862.17 RUS69736.1 - 0.0073 16.5 0.5 0.0086 16.3 0.5 1.2 1 0 0 1 1 1 1 DDHD domain Tim54 PF11711.8 RUS69736.1 - 0.024 13.5 8.2 0.029 13.1 8.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4770 PF15994.5 RUS69736.1 - 0.042 14.1 9.7 0.078 13.2 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) YL1 PF05764.13 RUS69736.1 - 0.049 13.8 22.8 0.065 13.3 22.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4228 PF14009.6 RUS69736.1 - 0.06 13.7 3.9 0.086 13.2 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Otopetrin PF03189.13 RUS69736.1 - 0.073 11.9 1.9 3.5 6.3 1.4 2.1 2 0 0 2 2 2 0 Otopetrin DUF5308 PF17233.2 RUS69736.1 - 0.13 12.4 0.5 0.72 10.1 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5308) SpoIIP PF07454.11 RUS69736.1 - 0.35 10.3 13.3 0.51 9.7 13.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EMC3_TMCO1 PF01956.16 RUS69736.1 - 0.41 10.4 10.2 0.68 9.6 10.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DNApol_Exo PF18136.1 RUS69736.1 - 1.1 8.4 11.4 16 4.5 12.0 2.0 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain BSMAP PF12280.8 RUS69736.1 - 1.1 9.4 6.2 2.4 8.3 6.2 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein Zip PF02535.22 RUS69736.1 - 1.4 8.1 5.3 1.9 7.6 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LicD PF04991.13 RUS69736.1 - 1.6 8.8 14.1 2.9 8.0 14.1 1.4 1 0 0 1 1 1 0 LicD family Connexin PF00029.19 RUS69736.1 - 2.5 7.8 16.9 4.1 7.1 16.9 1.3 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 RUS69736.1 - 2.6 7.0 5.4 4.6 6.2 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein RPOL_N PF14700.6 RUS69736.1 - 4.1 6.7 18.0 6.5 6.1 18.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal MDM10 PF12519.8 RUS69736.1 - 4.8 5.9 8.9 6.6 5.5 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Vfa1 PF08432.10 RUS69736.1 - 5.8 7.2 30.3 9.1 6.6 30.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 RUS69736.1 - 6.6 6.7 7.0 9.2 6.3 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3807 PF12720.7 RUS69736.1 - 8.2 6.7 24.7 12 6.1 24.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Rxt3 PF08642.10 RUS69736.1 - 9.3 7.0 9.2 16 6.3 9.2 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 HA2 PF04408.23 RUS69738.1 - 3.2e-24 85.3 0.2 7.6e-24 84.1 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS69738.1 - 3.7e-22 78.5 0.1 1.2e-21 76.8 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS69738.1 - 3.2e-12 46.8 0.0 8.9e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS69738.1 - 2.4e-07 30.7 0.1 5e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RUS69738.1 - 4.2e-05 23.9 0.1 0.00012 22.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS69738.1 - 0.00031 21.0 0.3 0.0049 17.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 RUS69738.1 - 0.003 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 RUS69738.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 RUS69738.1 - 0.013 15.0 0.0 0.073 12.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 RUS69738.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 RUS69738.1 - 0.042 13.8 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 RUS69738.1 - 0.051 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RUS69738.1 - 0.052 13.5 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 RUS69738.1 - 0.076 13.5 0.0 0.51 10.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 RUS69738.1 - 0.076 12.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 RUS69738.1 - 0.098 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain HTH_IclR PF09339.10 RUS69738.1 - 0.11 12.3 0.5 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain TrwB_AAD_bind PF10412.9 RUS69738.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Gly_acyl_tr_N PF06021.11 RUS69739.1 - 3.7e-19 69.6 0.0 6.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_1 PF00583.25 RUS69739.1 - 9.2e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RUS69739.1 - 0.0002 21.3 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RUS69739.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS69739.1 - 0.0045 17.4 0.0 0.0082 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 RUS69739.1 - 0.084 13.1 0.1 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region LRR_4 PF12799.7 RUS69740.1 - 6.8e-11 42.2 19.6 0.0055 17.1 0.4 8.2 9 2 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS69740.1 - 4.6e-08 32.5 12.0 4 7.7 0.1 10.2 11 0 0 11 11 11 2 Leucine Rich repeat Acetyltransf_14 PF03421.16 RUS69740.1 - 0.073 13.1 0.3 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 YopJ Serine/Threonine acetyltransferase Transp_inhibit PF18791.1 RUS69740.1 - 0.72 9.4 2.4 36 4.0 0.0 4.2 5 0 0 5 5 5 0 Transport inhibitor response 1 protein domain RVT_1 PF00078.27 RUS69741.1 - 1.5e-30 106.4 0.0 2.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_18 PF12847.7 RUS69742.1 - 0.00089 19.2 2.3 1.4 8.8 0.2 3.4 1 1 3 4 4 4 3 Methyltransferase domain DUF3641 PF12345.8 RUS69742.1 - 0.033 14.2 7.4 0.87 9.6 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) Trans_reg_C PF00486.28 RUS69742.1 - 0.93 9.6 13.8 23 5.1 0.2 4.7 1 1 7 8 8 8 0 Transcriptional regulatory protein, C terminal Integrase_H2C2 PF17921.1 RUS69743.1 - 2.1e-12 46.9 0.0 4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS69743.1 - 1.3e-08 35.1 0.0 2.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 RUS69743.1 - 4.4e-08 33.4 0.0 8.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS69743.1 - 0.00023 21.2 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TFB6 PF17110.5 RUS69744.1 - 0.00059 19.6 21.0 0.0072 16.1 5.0 2.2 2 0 0 2 2 2 2 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 RUS69744.1 - 0.026 14.2 1.3 0.026 14.2 1.3 3.3 2 1 0 2 2 2 0 FAM176 family SDA1 PF05285.12 RUS69744.1 - 0.028 13.9 39.3 0.023 14.1 7.5 2.0 2 0 0 2 2 2 0 SDA1 TIL PF01826.17 RUS69744.1 - 0.11 12.7 8.1 0.16 12.2 8.1 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Sigma70_ner PF04546.13 RUS69744.1 - 3 7.7 41.0 0.15 11.9 13.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Afi1 PF07792.12 RUS69744.1 - 9.4 6.7 24.8 3.3 8.2 5.7 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DEFB136 PF17333.2 RUS69745.1 - 0.039 13.9 2.4 0.039 13.9 2.4 3.6 3 0 0 3 3 3 0 Beta defensin 136 TIL PF01826.17 RUS69745.1 - 1.7 9.0 45.7 2.3 8.5 11.5 3.5 1 1 2 4 4 4 0 Trypsin Inhibitor like cysteine rich domain Ig_3 PF13927.6 RUS69746.1 - 0.00098 19.7 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS69746.1 - 0.01 16.1 0.0 0.034 14.5 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.25 RUS69746.1 - 0.027 14.7 0.2 0.072 13.3 0.2 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Sigma_1_2 PF03084.14 RUS69746.1 - 0.092 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Lectin_C PF00059.21 RUS69747.1 - 0.27 12.0 1.6 22 5.8 0.3 2.2 2 0 0 2 2 2 0 Lectin C-type domain Mg_trans_NIPA PF05653.14 RUS69748.1 - 5.8e-73 245.6 27.2 7.7e-73 245.2 27.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RUS69748.1 - 7.1e-08 32.7 2.0 7.1e-08 32.7 2.0 2.7 3 0 0 3 3 3 1 EamA-like transporter family XendoU PF09412.10 RUS69749.1 - 5.5e-91 304.5 0.0 6.8e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Patched PF02460.18 RUS69750.1 - 2.3e-109 366.7 10.6 3.6e-66 223.9 11.4 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 RUS69750.1 - 3e-14 53.1 1.7 3e-14 53.1 1.7 3.6 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RUS69751.1 - 8.6e-56 189.5 6.4 1e-55 189.2 6.4 1.0 1 0 0 1 1 1 1 Patched family Alpha-amyl_C PF09071.10 RUS69753.1 - 0.6 10.0 14.8 6.8 6.6 0.6 4.9 1 1 5 6 6 6 0 Alpha-amylase, C terminal AZUL PF16558.5 RUS69754.1 - 1.1 9.5 7.0 4 7.8 5.3 2.2 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A BUD22 PF09073.10 RUS69755.1 - 0.056 12.8 5.8 0.057 12.7 5.8 1.2 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.12 RUS69755.1 - 0.11 10.8 2.7 0.13 10.5 2.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TetR_C_31 PF17940.1 RUS69755.1 - 0.18 12.0 1.2 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Nop14 PF04147.12 RUS69755.1 - 2 6.5 15.0 2.6 6.2 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS69755.1 - 3.9 5.5 27.8 5.7 4.9 27.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DNA_pol_phi PF04931.13 RUS69756.1 - 8.4e-05 20.9 12.0 0.00012 20.4 12.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi FAM176 PF14851.6 RUS69756.1 - 0.47 10.1 1.9 1.2 8.7 1.9 1.7 1 0 0 1 1 1 0 FAM176 family RRM_5 PF13893.6 RUS69757.1 - 2.2e-52 175.9 0.1 6.3e-41 138.9 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RUS69757.1 - 5.3e-27 93.4 0.3 3.3e-07 30.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RUS69757.1 - 2.7e-13 49.9 0.0 6.3e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RRM-like domain Limkain-b1 PF11608.8 RUS69757.1 - 8.5e-06 25.8 0.2 0.017 15.2 0.0 2.8 3 0 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 RUS69757.1 - 1.5e-05 24.8 0.0 0.26 11.1 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 RUS69757.1 - 0.00045 20.2 0.1 1.6 8.8 0.0 3.3 4 0 0 4 4 4 2 RNA binding motif RL PF17797.1 RUS69757.1 - 0.0088 16.0 0.0 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 RL domain DUF4523 PF15023.6 RUS69757.1 - 0.086 12.7 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Nepo_coat_C PF03688.14 RUS69758.1 - 1.8 8.4 4.2 31 4.4 0.0 4.9 4 2 1 5 5 5 0 Nepovirus coat protein, C-terminal domain DUF3552 PF12072.8 RUS69759.1 - 0.0015 18.0 181.4 0.021 14.3 17.1 7.9 1 1 5 8 8 8 7 Domain of unknown function (DUF3552) Kinesin PF00225.23 RUS69760.1 - 3.8e-93 312.0 0.6 4.6e-93 311.8 0.6 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS69760.1 - 2e-18 66.8 0.2 5.3e-18 65.4 0.1 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 RUS69760.1 - 0.0028 18.1 0.0 0.0078 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS69760.1 - 0.0032 17.2 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Bap31_Bap29_C PF18035.1 RUS69760.1 - 0.027 14.5 1.0 0.071 13.1 1.0 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_23 PF13476.6 RUS69760.1 - 0.05 14.1 4.4 0.11 12.9 4.4 1.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 RUS69760.1 - 0.069 13.0 0.4 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_28 PF13521.6 RUS69761.1 - 1.6e-21 77.3 0.1 2.4e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain APP_amyloid PF10515.9 RUS69761.1 - 0.0075 16.7 0.3 0.086 13.4 0.3 2.4 2 0 0 2 2 2 1 Beta-amyloid precursor protein C-terminus MeaB PF03308.16 RUS69761.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad60-SLD PF11976.8 RUS69762.1 - 4.7e-14 52.0 0.8 1.2e-12 47.5 0.1 2.9 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RUS69762.1 - 0.00042 20.0 2.9 0.93 9.3 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family TUG-UBL1 PF11470.8 RUS69762.1 - 0.001 19.2 0.7 0.17 12.1 0.3 2.8 2 0 0 2 2 2 2 TUG ubiquitin-like domain SMAP PF15477.6 RUS69763.1 - 1.4e-14 54.8 2.6 1.4e-14 54.8 2.6 4.6 3 1 0 3 3 3 1 Small acidic protein family GST_C_3 PF14497.6 RUS69764.1 - 2.1e-13 50.3 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS69764.1 - 0.0086 16.5 0.0 0.026 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RUS69764.1 - 0.014 16.1 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 RUS69764.1 - 0.035 14.5 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_2 PF12796.7 RUS69765.1 - 7e-41 138.7 1.8 1.1e-13 51.6 0.0 5.5 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS69765.1 - 8e-35 118.5 4.1 2.4e-06 27.7 0.0 6.9 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS69765.1 - 2.4e-30 103.6 17.1 0.00011 22.4 0.2 9.7 9 1 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RUS69765.1 - 9.8e-30 99.3 2.8 0.0038 17.6 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 RUS69765.1 - 8.8e-29 99.5 7.5 5.2e-07 30.1 0.0 8.1 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Exo_endo_phos PF03372.23 RUS69766.1 - 0.00032 20.3 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS69766.1 - 0.022 14.6 0.4 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-C2H2_4 PF13894.6 RUS69768.1 - 0.00027 21.5 0.8 0.00027 21.5 0.8 4.3 2 2 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS69768.1 - 0.00071 19.9 1.0 0.00071 19.9 1.0 4.2 2 2 2 4 4 4 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 RUS69768.1 - 0.0041 17.4 2.8 0.0041 17.4 2.8 2.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS69768.1 - 0.0041 17.5 1.2 0.0041 17.5 1.2 3.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 RUS69768.1 - 0.017 14.9 5.0 0.02 14.7 0.3 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS69768.1 - 0.047 13.7 6.0 0.11 12.6 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger DUF5472 PF17566.2 RUS69768.1 - 0.063 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5472) DUF1610 PF07754.11 RUS69768.1 - 0.066 13.2 3.2 0.23 11.5 3.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-CCHC_5 PF14787.6 RUS69768.1 - 0.19 11.5 8.4 0.39 10.5 2.4 2.4 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zf_UBZ PF18439.1 RUS69768.1 - 0.48 10.0 8.2 0.22 11.2 0.6 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 RUS69768.1 - 1.2 8.6 10.1 0.18 11.2 1.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain EF-hand_8 PF13833.6 RUS69769.1 - 2.9e-09 36.6 1.9 0.00023 21.0 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 RUS69769.1 - 1.9e-08 34.7 5.2 0.00071 20.0 0.2 3.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS69769.1 - 2.7e-08 32.8 4.4 4.8e-05 22.6 0.5 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS69769.1 - 2.7e-08 33.1 3.8 0.00083 19.1 0.3 3.3 3 1 0 3 3 3 2 EF-hand domain ABM PF03992.16 RUS69769.1 - 6.3e-08 32.6 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_5 PF13202.6 RUS69769.1 - 1.3e-05 24.5 2.5 4.3e-05 22.8 0.4 2.6 2 0 0 2 2 2 1 EF hand AAA_23 PF13476.6 RUS69769.1 - 0.73 10.3 4.7 0.22 12.0 1.0 1.9 1 1 0 2 2 2 0 AAA domain RCR PF12273.8 RUS69770.1 - 0.013 16.1 0.7 0.046 14.4 0.7 1.9 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 RUS69770.1 - 0.015 15.1 5.6 0.091 12.6 0.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 51 SARAF PF06682.12 RUS69770.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Neur_chan_memb PF02932.16 RUS69770.1 - 0.14 12.2 0.4 0.13 12.3 0.4 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PMP1_2 PF08114.11 RUS69770.1 - 0.18 11.5 2.2 0.31 10.8 2.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family TMEM52 PF14979.6 RUS69770.1 - 0.59 10.0 5.0 27 4.7 5.0 2.7 1 1 0 1 1 1 0 Transmembrane 52 Sld5 PF05916.11 RUS69771.1 - 1.6e-07 31.8 0.0 2.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sina PF03145.16 RUS69772.1 - 4e-07 30.2 4.5 9.9e-07 28.9 3.9 1.8 1 1 0 1 1 1 1 Seven in absentia protein family zf-TRAF PF02176.18 RUS69772.1 - 1.9e-06 28.5 3.1 1.9e-06 28.5 3.1 2.5 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 RUS69772.1 - 0.00012 21.9 15.7 0.00012 21.9 15.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS69772.1 - 0.14 12.0 21.0 1.4 8.8 13.4 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS69772.1 - 1.6 8.6 20.1 0.2 11.5 13.7 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 RUS69773.1 - 1.1e-28 99.6 8.1 1.5e-16 60.7 0.5 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69773.1 - 3.9e-22 78.3 1.4 5e-09 36.5 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS69773.1 - 1.2e-19 70.1 0.6 1.2e-06 28.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS69773.1 - 4.4e-17 61.7 0.9 1.2e-05 25.5 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RUS69773.1 - 1.6e-14 52.6 0.0 8.9e-06 25.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat L27_1 PF09058.10 RUS69774.1 - 3.5e-31 107.0 0.6 5.5e-31 106.3 0.6 1.3 1 0 0 1 1 1 1 L27_1 Ras PF00071.22 RUS69775.1 - 2.8e-41 140.8 0.0 3.8e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS69775.1 - 8.9e-21 74.3 0.1 2e-20 73.2 0.1 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS69775.1 - 3.2e-08 33.2 0.1 3.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS69775.1 - 0.0048 16.3 0.3 0.011 15.1 0.1 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS69775.1 - 0.007 16.3 0.2 2.6 7.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS69775.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 RUS69775.1 - 0.038 13.5 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 RUS69775.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin LRR_8 PF13855.6 RUS69776.1 - 1e-15 57.2 16.8 1.1e-11 44.3 5.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS69776.1 - 6.8e-12 45.4 18.7 1.8e-06 28.2 1.7 3.6 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS69776.1 - 8.1e-06 25.5 11.3 0.32 11.2 0.4 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 RUS69776.1 - 0.00019 21.5 18.3 0.21 12.2 0.7 6.3 5 1 0 5 5 5 2 Leucine Rich Repeat MARVEL PF01284.23 RUS69777.1 - 0.043 13.8 4.2 0.38 10.8 0.1 2.9 2 1 0 2 2 2 0 Membrane-associating domain Ank_2 PF12796.7 RUS69779.1 - 1.1e-50 170.1 7.2 4.2e-11 43.3 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69779.1 - 1.9e-27 95.2 2.4 9.9e-05 22.8 0.0 6.5 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS69779.1 - 2.3e-26 91.5 3.2 0.00011 22.5 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS69779.1 - 8.8e-23 77.9 3.6 0.022 15.2 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 RUS69779.1 - 4.8e-20 71.1 10.7 0.00025 21.3 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat UQ_con PF00179.26 RUS69780.1 - 5e-30 104.0 0.0 7.9e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RUS69780.1 - 0.00017 21.4 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain AAA_lid_7 PF17867.1 RUS69780.1 - 0.0073 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain Prok-E2_B PF14461.6 RUS69780.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Glypican PF01153.19 RUS69780.1 - 2.9 6.6 14.1 0.076 11.8 0.6 2.1 2 0 0 2 2 2 0 Glypican Thioredoxin PF00085.20 RUS69781.1 - 3.2e-11 43.1 0.0 4.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 RUS69782.1 - 1.9e-100 329.7 16.1 7.5e-27 93.3 1.1 5.2 5 0 0 5 5 5 5 Thioredoxin Thioredoxin_2 PF13098.6 RUS69782.1 - 2.6e-28 98.7 8.0 6.8e-08 32.9 0.1 5.0 4 0 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RUS69782.1 - 8.6e-27 93.2 1.9 1.7e-07 31.3 0.0 4.7 4 0 0 4 4 4 4 Thioredoxin-like AhpC-TSA PF00578.21 RUS69782.1 - 1.4e-19 70.3 7.3 4.3e-06 26.7 0.0 5.0 5 0 0 5 5 5 4 AhpC/TSA family Thioredoxin_8 PF13905.6 RUS69782.1 - 9.1e-19 67.6 5.8 0.0042 17.4 0.0 6.8 5 2 1 6 6 6 5 Thioredoxin-like OST3_OST6 PF04756.13 RUS69782.1 - 3.1e-16 59.6 5.5 6.9e-05 22.3 0.0 4.7 4 1 1 5 5 5 3 OST3 / OST6 family, transporter family Redoxin PF08534.10 RUS69782.1 - 1.1e-13 51.1 6.6 0.029 14.1 0.0 4.7 5 0 0 5 5 5 4 Redoxin Thioredoxin_6 PF13848.6 RUS69782.1 - 9.3e-12 45.2 13.3 8.1e-05 22.6 0.0 5.0 4 1 0 4 4 4 3 Thioredoxin-like domain TraF PF13728.6 RUS69782.1 - 1.1e-08 35.3 13.1 6.5e-05 22.9 0.0 5.3 5 2 1 6 6 6 3 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 RUS69782.1 - 2e-07 30.8 1.4 1.2 8.9 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin Glutaredoxin PF00462.24 RUS69782.1 - 9.2e-07 29.0 12.1 1.1 9.5 0.1 5.2 4 1 0 4 4 4 3 Glutaredoxin DUF836 PF05768.14 RUS69782.1 - 5.6e-06 26.7 0.1 0.22 12.0 0.0 4.1 4 0 0 4 4 4 2 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 RUS69782.1 - 3.9e-05 23.6 7.9 0.92 9.6 0.0 5.6 5 1 1 6 6 6 2 Thioredoxin domain DUF953 PF06110.11 RUS69782.1 - 0.00048 19.7 0.4 0.28 10.8 0.0 3.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 RUS69782.1 - 0.00096 19.1 0.1 0.56 10.2 0.1 3.2 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE PMSI1 PF15322.6 RUS69782.1 - 0.2 11.0 1.6 3.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein missing in infertile sperm 1, putative Thioredoxin_5 PF13743.6 RUS69782.1 - 5.2 6.7 12.5 18 5.0 0.1 5.7 5 3 1 6 6 6 0 Thioredoxin PAN_1 PF00024.26 RUS69783.1 - 0.00023 21.0 0.8 0.00047 20.1 0.8 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RUS69783.1 - 0.052 13.4 1.0 0.11 12.4 1.0 1.6 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 RUS69783.1 - 0.069 13.0 1.3 0.13 12.1 1.3 1.4 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.14 RUS69784.1 - 0.0061 15.4 1.2 3.7 6.3 0.0 3.3 2 1 1 3 3 3 2 Oligosaccharyltransferase 48 kDa subunit beta Zea_mays_MuDR PF05928.11 RUS69784.1 - 0.075 12.7 1.3 13 5.4 0.0 3.6 1 1 3 5 5 5 0 Zea mays MURB-like protein (MuDR) DUF1181 PF06680.11 RUS69784.1 - 0.5 10.2 4.2 29 4.5 0.1 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1181) Pkinase PF00069.25 RUS69785.1 - 8.4e-63 212.2 0.0 1.3e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69785.1 - 5.1e-40 137.4 0.0 7.8e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RUS69785.1 - 3.9e-29 100.3 31.1 1.1e-15 57.2 7.6 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 RUS69785.1 - 2.4e-07 31.3 0.6 5.5e-07 30.2 0.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 RUS69785.1 - 0.0027 18.0 20.1 0.081 13.2 6.4 2.6 2 0 0 2 2 2 2 C1 domain FTA2 PF13095.6 RUS69785.1 - 0.0085 15.7 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS69785.1 - 0.029 14.3 0.1 0.086 12.7 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zf_RING PF16744.5 RUS69785.1 - 0.035 14.2 12.4 0.25 11.5 3.1 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger Kinase-like PF14531.6 RUS69785.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 RUS69785.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ATG7_N PF16420.5 RUS69787.1 - 5.4e-95 318.5 0.0 7.8e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 RUS69787.1 - 2.4e-46 158.1 0.0 3.7e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 RUS69787.1 - 0.0042 16.5 0.0 0.062 12.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 RUS69787.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 RUS69787.1 - 0.033 14.2 0.1 0.91 9.6 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Leu_Phe_trans PF03588.14 RUS69788.1 - 0.048 13.2 0.8 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase LEAP-2 PF07359.11 RUS69788.1 - 0.049 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) SNARE PF05739.19 RUS69788.1 - 0.85 9.7 2.6 3.3 7.8 0.7 2.4 2 0 0 2 2 2 0 SNARE domain Macoilin PF09726.9 RUS69788.1 - 2.3 6.7 15.8 3.1 6.3 15.8 1.1 1 0 0 1 1 1 0 Macoilin family RVT_3 PF13456.6 RUS69791.1 - 3.6e-05 23.6 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Peptidase_C65 PF10275.9 RUS69791.1 - 0.11 11.9 0.9 0.14 11.6 0.1 1.5 2 0 0 2 2 2 0 Peptidase C65 Otubain OAD_gamma PF04277.13 RUS69791.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Exo_endo_phos_2 PF14529.6 RUS69793.1 - 5.3e-07 29.5 2.9 5.5e-07 29.4 0.4 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Speriolin_C PF15059.6 RUS69793.1 - 0.017 15.2 0.0 5.9 7.0 0.0 2.4 1 1 1 2 2 2 0 Speriolin C-terminus DUF1540 PF07561.11 RUS69793.1 - 0.02 15.1 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) DUF5444 PF17519.2 RUS69793.1 - 0.023 14.7 0.2 24 5.0 0.0 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5444) TetR_C_3 PF08362.11 RUS69793.1 - 0.039 13.9 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region FAM25 PF15825.5 RUS69793.1 - 0.063 13.6 0.0 26 5.2 0.0 2.7 2 1 0 2 2 2 0 FAM25 family DUF3887 PF13026.6 RUS69793.1 - 0.099 13.5 0.9 22 6.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) Peptidase_A17 PF05380.13 RUS69793.1 - 0.12 12.4 6.7 2.7 8.0 0.5 2.4 2 0 0 2 2 2 0 Pao retrotransposon peptidase Doppel PF11466.8 RUS69794.1 - 0.17 11.6 0.6 0.39 10.4 0.6 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel FAM220 PF15487.6 RUS69796.1 - 1.5e-76 257.7 0.0 4.1e-76 256.2 0.0 1.8 2 1 0 2 2 2 1 FAM220 family Ank_2 PF12796.7 RUS69796.1 - 3e-17 63.0 2.9 2.6e-09 37.5 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS69796.1 - 2.5e-12 45.8 6.1 0.00033 20.8 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RUS69796.1 - 2.8e-09 37.4 4.7 7.4e-06 26.4 0.5 3.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS69796.1 - 4.3e-09 36.4 7.8 0.00049 20.4 0.4 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RUS69796.1 - 3.2e-08 33.7 1.8 0.0031 17.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) adh_short PF00106.25 RUS69797.1 - 8.7e-39 133.0 0.3 1.1e-38 132.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS69797.1 - 2.6e-25 89.4 0.6 4.3e-25 88.6 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS69797.1 - 4.2e-07 30.0 1.8 1.6e-06 28.2 1.8 1.7 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 RUS69797.1 - 0.0002 21.4 0.0 0.0004 20.5 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 RUS69797.1 - 0.0022 17.5 0.1 0.0026 17.3 0.1 1.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RUS69797.1 - 0.0059 16.5 0.1 0.007 16.3 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 RUS69797.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS69797.1 - 0.073 12.2 0.1 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_21 PF05050.12 RUS69798.1 - 2e-10 40.9 0.0 1.3e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 RUS69798.1 - 0.097 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain V_cholerae_RfbT PF05575.11 RUS69798.1 - 0.17 11.1 0.0 14 4.8 0.0 2.1 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein SAPS PF04499.15 RUS69799.1 - 0.11 11.2 13.8 0.15 10.8 13.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Annexin PF00191.20 RUS69800.1 - 3.8e-55 183.8 8.8 4.3e-21 74.8 0.2 4.1 4 0 0 4 4 4 4 Annexin FAM220 PF15487.6 RUS69801.1 - 0.05 13.2 0.7 0.099 12.3 0.7 1.5 1 0 0 1 1 1 0 FAM220 family zf-H2C2_2 PF13465.6 RUS69802.1 - 6.6e-27 92.7 28.4 2.8e-08 33.8 0.9 6.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 RUS69802.1 - 2.4e-26 90.7 31.8 8e-06 26.0 0.3 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69802.1 - 2.5e-23 80.8 28.1 0.00016 22.2 0.4 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS69802.1 - 1.8e-16 59.7 24.9 1.6e-05 24.8 0.6 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 RUS69802.1 - 1.4e-14 53.9 18.7 0.0019 18.5 0.1 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS69802.1 - 3.3e-14 52.7 5.1 0.0029 17.8 0.0 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS69802.1 - 8.4e-07 28.6 27.0 0.016 15.0 0.5 5.3 5 1 0 5 5 5 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RUS69802.1 - 0.00011 22.3 9.3 0.0035 17.4 1.0 4.1 3 1 2 5 5 4 1 Zinc ribbon domain zf-C2HC_2 PF13913.6 RUS69802.1 - 0.0003 20.6 23.7 0.013 15.4 0.3 5.4 5 1 0 5 5 5 2 zinc-finger of a C2HC-type zf-Dof PF02701.15 RUS69802.1 - 0.00078 19.5 4.2 0.29 11.3 0.7 2.8 1 1 1 2 2 2 2 Dof domain, zinc finger Zn-C2H2_12 PF18112.1 RUS69802.1 - 0.00092 19.6 10.5 0.67 10.5 0.3 4.7 5 0 0 5 5 4 2 Autophagy receptor zinc finger-C2H2 domain Zn_ribbon_SprT PF17283.2 RUS69802.1 - 0.002 18.0 12.8 0.064 13.2 0.4 3.8 3 1 1 4 4 4 2 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 RUS69802.1 - 0.0035 17.7 14.2 0.27 11.6 1.4 4.5 1 1 4 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RUS69802.1 - 0.0036 17.7 12.8 1.4 9.4 0.5 4.1 2 1 2 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 RUS69802.1 - 0.0036 18.0 7.5 0.88 10.4 0.5 3.0 2 1 0 2 2 2 2 zinc-ribbon family zf_UBZ PF18439.1 RUS69802.1 - 0.0077 15.8 11.2 6.5 6.4 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zf_RING PF16744.5 RUS69802.1 - 0.0083 16.2 10.0 1.9 8.7 0.6 4.1 1 1 2 4 4 4 1 KIAA1045 RING finger zf-C2H2_9 PF16293.5 RUS69802.1 - 0.023 14.6 0.3 0.023 14.6 0.3 3.7 5 0 0 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-AN1 PF01428.16 RUS69802.1 - 0.043 14.0 9.6 4.1 7.7 0.1 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger PHD_Oberon PF07227.11 RUS69802.1 - 0.065 13.1 0.6 0.065 13.1 0.6 2.5 1 1 2 3 3 3 0 PHD - plant homeodomain finger protein zf-trcl PF13451.6 RUS69802.1 - 0.076 12.9 8.6 13 5.8 1.2 3.8 3 1 0 3 3 3 0 Probable zinc-ribbon domain zf-LYAR PF08790.11 RUS69802.1 - 0.094 12.6 15.0 2.4 8.1 0.1 5.1 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger FYDLN_acid PF09538.10 RUS69802.1 - 0.1 13.3 1.5 66 4.3 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) FYVE PF01363.21 RUS69802.1 - 0.21 11.8 20.0 4 7.6 11.0 4.2 1 1 3 4 4 4 0 FYVE zinc finger GAGA PF09237.11 RUS69802.1 - 0.21 11.4 5.7 1 9.2 0.4 3.3 2 1 2 4 4 4 0 GAGA factor LIM PF00412.22 RUS69802.1 - 0.22 11.8 7.9 12 6.2 0.0 3.5 2 1 1 3 3 3 0 LIM domain zf-C3HC4_2 PF13923.6 RUS69802.1 - 0.26 11.2 3.5 24 4.9 0.0 4.0 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) BolA PF01722.18 RUS69802.1 - 0.33 11.2 3.4 8.8 6.7 0.0 3.2 2 1 2 4 4 4 0 BolA-like protein Cript PF10235.9 RUS69802.1 - 0.52 10.9 9.1 14 6.3 0.0 3.6 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT DUF2256 PF10013.9 RUS69802.1 - 0.7 10.1 12.9 2.1 8.5 0.3 4.2 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 RUS69802.1 - 0.76 9.9 10.2 1.2e+02 2.8 10.2 2.9 1 1 0 1 1 1 0 Double zinc ribbon zf-met2 PF12907.7 RUS69802.1 - 0.94 9.7 11.3 5.6 7.2 0.4 3.7 3 1 0 3 3 3 0 Zinc-binding PHD_4 PF16866.5 RUS69802.1 - 1 9.5 4.3 2.1 8.5 0.4 2.8 3 0 0 3 3 2 0 PHD-finger ADK_lid PF05191.14 RUS69802.1 - 1.5 8.9 5.9 1.1 9.4 0.3 3.1 3 1 1 4 4 3 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 RUS69802.1 - 1.6 8.3 5.4 9.1 5.9 0.3 3.4 4 0 0 4 4 3 0 TFIIB zinc-binding zf_C2H2_ZHX PF18387.1 RUS69802.1 - 1.8 8.3 6.7 4.2 7.1 0.1 3.7 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain BIR PF00653.21 RUS69802.1 - 2.4 8.9 9.3 0.65 10.7 1.6 2.9 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain XPA_N PF01286.18 RUS69802.1 - 3 8.0 10.1 35 4.6 0.1 4.0 5 0 0 5 5 4 0 XPA protein N-terminal zf-Sec23_Sec24 PF04810.15 RUS69802.1 - 3.6 7.7 13.3 22 5.2 0.2 4.0 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 RUS69802.1 - 3.8 7.6 12.7 16 5.7 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger domain CTU2 PF10288.9 RUS69802.1 - 4.3 7.6 8.4 8.4e+02 0.2 8.4 3.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF629 PF04780.12 RUS69802.1 - 4.5 5.7 11.6 7.1 5.0 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF629) zf-DNA_Pol PF08996.10 RUS69802.1 - 4.7 6.9 8.6 9.5 5.9 4.5 2.6 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Desulfoferrod_N PF06397.12 RUS69802.1 - 7.3 6.3 10.9 29 4.4 0.1 4.4 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-BED PF02892.15 RUS69802.1 - 9.6 6.3 22.6 15 5.7 3.9 5.1 2 1 3 5 5 5 0 BED zinc finger zf-H2C2_5 PF13909.6 RUS69804.1 - 5.2e-12 45.3 12.0 0.00011 21.8 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 RUS69804.1 - 1.7e-08 34.6 9.2 5.3e-06 26.6 0.9 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RUS69804.1 - 3.1e-06 27.6 24.3 0.04 14.8 0.8 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS69804.1 - 1.5e-05 25.2 16.4 0.0086 16.5 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS69804.1 - 0.00013 22.2 22.1 0.026 15.0 0.8 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_7 PF15269.6 RUS69804.1 - 0.00014 21.8 0.2 1 9.5 0.0 3.0 2 1 1 3 3 3 2 Zinc-finger zf_C2H2_ZHX PF18387.1 RUS69804.1 - 0.00021 20.9 6.6 2 8.1 0.1 3.5 1 1 2 3 3 3 3 Zinc-fingers and homeoboxes C2H2 finger domain DMP12 PF16779.5 RUS69804.1 - 0.0015 18.5 6.7 8 6.5 0.3 4.4 1 1 4 5 5 5 1 DNA-mimic protein Galactosyl_T PF01762.21 RUS69804.1 - 0.0091 15.8 17.2 1e+02 2.6 0.1 7.6 3 1 3 8 8 8 0 Galactosyltransferase zf-C2H2_9 PF16293.5 RUS69804.1 - 0.017 15.0 6.2 4.1 7.3 0.0 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) OrsD PF12013.8 RUS69804.1 - 0.14 12.7 8.3 5.7 7.4 0.1 3.5 3 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 RUS69804.1 - 0.21 11.9 11.3 11 6.4 0.3 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1059 PF06348.11 RUS69804.1 - 0.65 10.3 2.5 32 4.8 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1059) RMP PF14996.6 RUS69804.1 - 0.69 10.1 6.9 0.65 10.2 4.8 2.0 1 1 0 1 1 1 0 Retinal Maintenance Phage_Integr_2 PF13009.6 RUS69804.1 - 0.81 8.7 6.6 5.6 6.0 1.0 2.5 1 1 1 2 2 2 0 Putative phage integrase DUF4451 PF14616.6 RUS69804.1 - 1.1 9.5 9.5 8.6 6.6 9.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-BED PF02892.15 RUS69804.1 - 1.3 9.1 12.3 1.7 8.7 0.0 3.3 2 1 2 4 4 4 0 BED zinc finger FOXP-CC PF16159.5 RUS69804.1 - 1.5 9.5 4.2 46 4.8 0.1 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain Tropomyosin PF00261.20 RUS69804.1 - 2.9 7.2 7.5 45 3.3 0.3 3.0 1 1 3 4 4 4 0 Tropomyosin DUF4337 PF14235.6 RUS69805.1 - 8.6 6.5 12.1 21 5.2 12.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CUB PF00431.20 RUS69807.1 - 1.8e-47 160.2 0.0 3.7e-26 91.6 0.0 2.1 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 RUS69807.1 - 2.4e-06 27.3 0.8 0.011 15.5 0.4 2.6 2 1 0 2 2 2 2 CUB-like domain IL12p40_C PF10420.9 RUS69807.1 - 0.0076 16.7 0.3 2.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Cytokine interleukin-12p40 C-terminus C1ORF64 PF15547.6 RUS69809.1 - 0.059 13.8 0.0 0.074 13.5 0.0 1.2 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein FMO-like PF00743.19 RUS69810.1 - 3.8e-108 362.2 0.5 3.9e-42 144.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS69810.1 - 0.00019 20.8 0.1 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MAGE PF01454.19 RUS69811.1 - 7.5e-30 104.2 2.1 1.3e-28 100.2 2.1 2.0 1 1 0 1 1 1 1 MAGE family CaM_binding PF07839.11 RUS69811.1 - 0.029 15.1 0.2 0.33 11.7 0.1 2.4 2 1 0 2 2 2 0 Plant calmodulin-binding domain PGM_PMM_II PF02879.16 RUS69811.1 - 0.076 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Gar1 PF04410.14 RUS69812.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region 7tm_1 PF00001.21 RUS69814.1 - 1.1e-27 97.1 6.2 1.7e-27 96.4 6.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS69814.1 - 0.00032 20.1 12.8 0.025 14.0 0.9 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS69814.1 - 0.0075 15.9 5.0 0.0075 15.9 5.0 2.5 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx XPG_N PF00752.17 RUS69815.1 - 2.9e-31 107.9 0.0 4.5e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RUS69815.1 - 8.8e-21 74.1 0.0 2.1e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 RUS69815.1 - 0.026 14.0 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing APG6_N PF17675.1 RUS69816.1 - 0.073 13.6 4.7 0.1 13.1 4.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MeaB PF03308.16 RUS69816.1 - 0.21 10.5 0.8 0.33 9.9 0.8 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Exonuc_VII_L PF02601.15 RUS69816.1 - 1.1 8.8 4.9 1.4 8.4 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SBP56 PF05694.11 RUS69818.1 - 6e-185 615.4 0.0 6.8e-185 615.2 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 RUS69818.1 - 4.6e-07 29.4 0.0 0.00018 20.9 0.0 2.9 2 1 0 3 3 3 2 Lactonase, 7-bladed beta-propeller NFRKB_winged PF14465.6 RUS69820.1 - 1.5e-20 73.3 0.2 5.7e-20 71.4 0.1 2.0 2 0 0 2 2 2 1 NFRKB Winged Helix-like NTPase_1 PF03266.15 RUS69822.1 - 3.2e-49 167.0 0.0 3.7e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 RUS69822.1 - 3e-05 24.5 0.0 4.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS69822.1 - 0.00035 20.9 0.1 0.00096 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 RUS69822.1 - 0.00071 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 RUS69822.1 - 0.0017 18.7 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS69822.1 - 0.0024 17.6 0.0 0.005 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RUS69822.1 - 0.0025 17.9 0.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RUS69822.1 - 0.0029 17.4 0.1 0.017 14.9 0.1 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 RUS69822.1 - 0.0032 18.0 0.1 0.0043 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 RUS69822.1 - 0.005 17.3 0.1 0.0073 16.7 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 RUS69822.1 - 0.0078 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Arf PF00025.21 RUS69822.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RuvB_N PF05496.12 RUS69822.1 - 0.012 15.3 0.1 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 RUS69822.1 - 0.013 15.9 0.4 0.052 13.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS69822.1 - 0.014 15.2 0.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS69822.1 - 0.021 14.7 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 RUS69822.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 RUS69822.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 RUS69822.1 - 0.038 14.2 0.1 0.083 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 RUS69822.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 RUS69822.1 - 0.049 13.2 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_3 PF07726.11 RUS69822.1 - 0.07 13.0 0.1 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 RUS69822.1 - 0.074 13.1 0.2 0.12 12.5 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 RUS69822.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cas9_C PF18525.1 RUS69822.1 - 0.096 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Cas9 C-terminal domain ATP_bind_1 PF03029.17 RUS69822.1 - 0.17 11.7 0.1 0.74 9.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Homeodomain PF00046.29 RUS69823.1 - 4.8e-16 58.3 0.9 1.3e-15 57.0 0.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS69823.1 - 2.1e-05 24.3 0.5 2.1e-05 24.3 0.5 2.2 2 0 0 2 2 2 1 Homeobox KN domain eIF3_subunit PF08597.10 RUS69823.1 - 3.9 7.3 8.9 1.7 8.5 1.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit ANF_receptor PF01094.28 RUS69824.1 - 2.2e-17 63.2 0.1 2.7e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Radical_SAM PF04055.21 RUS69825.1 - 8.7e-21 75.0 0.0 2.1e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 RUS69825.1 - 3.2e-05 23.9 0.0 6.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM_C PF16199.5 RUS69825.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Radical_SAM C-terminal domain TFCD_C PF12612.8 RUS69826.1 - 1.4e-55 188.1 0.0 5.9e-55 186.0 0.0 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 RUS69826.1 - 7.9e-07 28.8 10.5 0.57 10.6 0.0 8.7 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 RUS69826.1 - 1.4e-06 28.7 6.0 2.6 8.7 0.2 6.8 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RUS69826.1 - 0.0037 17.8 1.2 1.8 9.2 0.0 4.5 2 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RUS69826.1 - 0.0052 16.8 1.1 0.14 12.2 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Pro_3_hydrox_C PF05373.11 RUS69826.1 - 0.026 14.6 0.0 0.097 12.8 0.0 2.0 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Rif1_N PF12231.8 RUS69826.1 - 0.083 11.9 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal DUF3837 PF12939.7 RUS69826.1 - 0.11 12.9 0.1 29 5.1 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) HEAT_2 PF13646.6 RUS69826.1 - 0.19 12.1 5.6 1.6 9.2 0.1 4.8 6 2 0 6 6 6 0 HEAT repeats Activator_LAG-3 PF11498.8 RUS69827.1 - 0.055 12.4 0.3 0.083 11.8 0.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_L7Ae PF01248.26 RUS69828.1 - 4e-32 109.8 4.4 6.7e-28 96.3 1.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SH3_15 PF18346.1 RUS69828.1 - 0.029 14.7 0.5 4.2 7.8 0.1 2.2 1 1 1 2 2 2 0 Mind bomb SH3 repeat domain FOLN PF09289.10 RUS69828.1 - 0.1 12.8 2.7 12 6.2 0.2 2.7 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain BLACT_WH PF17778.1 RUS69828.1 - 0.11 12.6 0.1 28 4.8 0.0 2.6 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Ins134_P3_kin_N PF17927.1 RUS69828.1 - 0.14 12.6 0.0 2 8.9 0.0 2.2 1 1 1 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain YbfN PF13982.6 RUS69828.1 - 0.14 12.4 3.8 2.7 8.3 0.2 2.7 2 1 1 3 3 3 0 YbfN-like lipoprotein PH PF00169.29 RUS69829.1 - 1.1e-14 54.9 2.4 2e-14 53.9 1.6 1.8 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 RUS69829.1 - 6.5e-05 23.3 0.5 0.008 16.5 0.5 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain SH2 PF00017.24 RUS69829.1 - 0.00067 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_11 PF15413.6 RUS69829.1 - 2.8 8.4 9.7 2.2 8.8 4.5 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain Ribosomal_L28e PF01778.17 RUS69830.1 - 1.8e-36 125.4 1.3 1.8e-36 125.4 1.3 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 RUS69830.1 - 5e-27 94.4 14.2 5e-27 94.4 14.2 2.0 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 RUS69830.1 - 0.0007 19.1 14.7 0.00085 18.8 14.7 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RUS69830.1 - 0.042 12.1 19.9 0.053 11.7 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nop14 PF04147.12 RUS69831.1 - 4.9e-06 25.1 25.1 5.1e-06 25.0 25.1 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS69831.1 - 5e-05 21.8 24.4 5.8e-05 21.6 24.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 RUS69831.1 - 0.0033 16.0 21.6 0.0038 15.8 21.6 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 RUS69831.1 - 0.0058 16.1 35.5 0.0066 15.9 35.5 1.1 1 0 0 1 1 1 1 SDA1 Apt1 PF10351.9 RUS69831.1 - 0.026 13.4 1.9 0.033 13.0 1.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SpoIIIAH PF12685.7 RUS69831.1 - 0.38 10.6 6.7 0.46 10.3 6.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 RUS69831.1 - 1 8.1 10.4 1.2 7.9 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RUS69831.1 - 2.3 7.5 32.9 2.6 7.3 32.9 1.1 1 0 0 1 1 1 0 BUD22 SPA PF08616.10 RUS69832.1 - 1e-09 38.4 0.1 1.5e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 RUS69832.1 - 2.9e-09 36.9 0.0 5.6e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 RUS69832.1 - 3.3e-05 22.8 0.1 0.0034 16.1 0.0 2.2 1 1 0 2 2 2 2 Transport protein Avl9 YjbR PF04237.13 RUS69832.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 YjbR Bromodomain PF00439.25 RUS69833.1 - 1.4e-19 69.9 0.1 5.7e-19 68.0 0.1 1.9 1 1 1 2 2 2 1 Bromodomain Endonuc_Holl PF10107.9 RUS69833.1 - 0.97 9.3 0.0 0.97 9.3 0.0 3.4 3 1 1 4 4 4 0 Endonuclease related to archaeal Holliday junction resolvase BLOC1_2 PF10046.9 RUS69835.1 - 0.12 12.7 3.5 0.24 11.7 3.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1361 PF07099.11 RUS69836.1 - 0.0041 17.1 2.1 0.0087 16.0 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) Claudin_2 PF13903.6 RUS69836.1 - 0.014 15.2 0.1 0.014 15.2 0.1 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3040 PF11239.8 RUS69836.1 - 1.8 8.9 4.8 18 5.7 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Rhodanese PF00581.20 RUS69837.1 - 7.4e-12 45.7 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ADAM_CR_2 PF17771.1 RUS69838.1 - 7.4e-11 42.4 2.9 7.4e-11 42.4 2.9 2.2 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin PF01421.19 RUS69838.1 - 7.2e-09 35.8 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS69838.1 - 0.00032 20.9 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 RUS69838.1 - 0.0008 19.1 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS69838.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 1.8 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS69838.1 - 0.0037 17.8 0.0 0.0058 17.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M48 PF01435.18 RUS69838.1 - 0.043 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M10 PF00413.24 RUS69838.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 RUS69838.1 - 0.13 11.5 0.2 0.18 11.0 0.2 1.1 1 0 0 1 1 1 0 Met-zincin WLM PF08325.10 RUS69838.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 WLM domain Phage_antitermQ PF06530.12 RUS69839.1 - 0.066 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q DUF229 PF02995.17 RUS69840.1 - 1.7e-93 313.9 1.5 1.7e-93 313.9 1.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS69840.1 - 2.7e-07 30.3 0.7 7.8e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.22 RUS69840.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Zwilch PF09817.9 RUS69841.1 - 3e-23 82.1 4.8 5.5e-23 81.3 4.8 1.4 1 1 0 1 1 1 1 RZZ complex, subunit zwilch Hemocyanin_N PF03722.14 RUS69841.1 - 0.026 15.0 0.1 0.16 12.5 0.1 2.2 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Lectin_C PF00059.21 RUS69842.1 - 5.4e-25 88.2 0.1 2.4e-11 44.3 0.0 2.9 2 1 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 RUS69842.1 - 1.8e-06 27.7 0.6 0.031 13.9 0.1 2.3 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 RUS69842.1 - 0.012 14.9 0.4 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Lectin_C PF00059.21 RUS69843.1 - 4.2e-23 82.1 0.1 1.2e-10 42.1 0.0 3.6 3 0 0 3 3 3 2 Lectin C-type domain DUF745 PF05335.13 RUS69843.1 - 5.7e-15 55.5 44.9 8.1e-06 25.7 3.4 6.6 1 1 6 7 7 7 6 Protein of unknown function (DUF745) Spc7 PF08317.11 RUS69843.1 - 4.6e-12 45.5 50.7 0.0026 16.7 4.4 4.8 1 1 4 5 5 5 4 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 RUS69843.1 - 3.7e-09 36.7 50.2 0.098 12.7 4.2 9.4 2 1 3 7 7 7 4 TPR/MLP1/MLP2-like protein Filament PF00038.21 RUS69843.1 - 1.9e-08 34.2 50.9 0.12 11.9 0.5 6.8 1 1 6 7 7 7 5 Intermediate filament protein FliJ PF02050.16 RUS69843.1 - 1.1e-07 32.1 1.0 1.6 8.9 0.0 5.1 2 2 2 5 5 5 1 Flagellar FliJ protein WEMBL PF05701.11 RUS69843.1 - 5.5e-07 28.7 56.1 0.00027 19.8 21.7 3.9 1 1 2 3 3 3 3 Weak chloroplast movement under blue light UL45 PF05473.12 RUS69843.1 - 3.1e-05 23.7 0.7 0.3 10.7 0.1 2.9 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like DUF3584 PF12128.8 RUS69843.1 - 5.8e-05 20.8 54.2 0.011 13.3 16.7 4.2 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) KxDL PF10241.9 RUS69843.1 - 0.00019 21.6 53.2 0.6 10.4 2.2 10.9 1 1 12 14 14 14 2 Uncharacterized conserved protein EzrA PF06160.12 RUS69843.1 - 0.00026 19.3 37.0 0.012 13.9 6.7 4.6 1 1 2 4 4 4 3 Septation ring formation regulator, EzrA MscS_porin PF12795.7 RUS69843.1 - 0.00047 19.8 33.3 0.11 12.0 8.6 5.0 1 1 4 6 6 6 4 Mechanosensitive ion channel porin domain OEP PF02321.18 RUS69843.1 - 0.004 17.0 1.7 11 5.8 0.0 4.6 4 0 0 4 4 4 0 Outer membrane efflux protein Fez1 PF06818.15 RUS69843.1 - 0.016 15.7 60.2 0.089 13.2 16.1 5.2 1 1 4 5 5 5 0 Fez1 Golgin_A5 PF09787.9 RUS69843.1 - 0.13 11.7 48.9 0.15 11.5 7.2 4.4 1 1 3 4 4 4 0 Golgin subfamily A member 5 AIP3 PF03915.13 RUS69843.1 - 0.47 9.5 66.2 0.0078 15.3 19.3 4.0 1 1 2 3 3 3 0 Actin interacting protein 3 HOIP-UBA PF16678.5 RUS69843.1 - 4.3 7.3 30.2 4.5 7.3 1.4 5.4 2 2 2 5 5 5 0 HOIP UBA domain pair PE PF00934.20 RUS69843.1 - 8.2 6.8 7.0 1.2e+02 3.1 0.0 4.9 5 0 0 5 5 5 0 PE family YscO PF07321.12 RUS69843.1 - 8.3 6.4 11.1 17 5.3 0.5 4.4 3 3 2 6 6 6 0 Type III secretion protein YscO SRCR PF00530.18 RUS69844.1 - 3.6e-17 62.7 0.2 5.5e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS69844.1 - 1.1e-06 29.0 0.2 3e-06 27.7 0.2 1.8 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain PKcGMP_CC PF16808.5 RUS69844.1 - 0.014 15.2 2.0 0.03 14.2 2.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 RUS69844.1 - 0.014 15.7 0.1 0.022 15.1 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Hepsin-SRCR PF09272.10 RUS69844.1 - 0.018 15.6 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Hepsin, SRCR domain HMMR_N PF15905.5 RUS69844.1 - 0.058 12.9 0.2 0.076 12.5 0.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal VGPC1_C PF16799.5 RUS69844.1 - 0.22 11.5 1.1 0.42 10.6 1.1 1.4 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ANF_receptor PF01094.28 RUS69845.1 - 1.6e-08 34.0 0.0 2.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS69845.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein p450 PF00067.22 RUS69847.1 - 7.7e-26 90.8 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NGP1NT PF08153.12 RUS69848.1 - 1.2e-45 154.8 0.8 2.1e-45 154.1 0.8 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 RUS69848.1 - 9.2e-18 64.4 0.0 1.9e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS69848.1 - 2.7e-06 27.0 0.3 1.7e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS69848.1 - 1.8e-05 24.7 0.0 4.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 RUS69848.1 - 0.0034 16.8 0.1 0.074 12.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 RUS69848.1 - 0.0076 16.3 0.4 0.74 9.8 0.1 3.1 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 RUS69848.1 - 0.074 13.6 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RUS69848.1 - 0.29 10.8 0.8 4.8 6.8 0.5 2.1 1 1 1 2 2 2 0 AAA ATPase domain EIF_2_alpha PF07541.12 RUS69849.1 - 3.6e-34 117.3 0.0 7.9e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 RUS69849.1 - 3e-16 59.5 0.9 6.2e-16 58.5 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain UCH PF00443.29 RUS69850.1 - 4e-47 160.9 0.0 5.2e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS69850.1 - 7.7e-12 45.4 0.1 2.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RUS69850.1 - 0.01 15.6 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family Peptidase_C98 PF15499.6 RUS69850.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Kinesin PF00225.23 RUS69851.1 - 1.3e-63 214.9 0.2 1.5e-63 214.7 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS69851.1 - 3.1e-22 79.1 0.3 5.5e-22 78.3 0.1 1.4 2 0 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 RUS69851.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS69851.1 - 0.035 14.4 0.0 0.076 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RUS69851.1 - 0.043 13.3 0.2 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region CreA PF05981.12 RUS69851.1 - 0.063 13.3 0.0 0.29 11.1 0.0 2.1 2 1 1 3 3 3 0 CreA protein ResIII PF04851.15 RUS69851.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RUS69851.1 - 0.097 13.0 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Gly_acyl_tr_C PF08444.10 RUS69851.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region TMIE PF16038.5 RUS69852.1 - 3.4e-17 62.1 1.8 4.8e-17 61.6 1.8 1.2 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 RUS69852.1 - 0.0025 18.1 0.0 0.0034 17.7 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Ni_hydr_CYTB PF01292.20 RUS69852.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Vpu PF00558.19 RUS69852.1 - 0.11 12.3 1.7 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Vpu protein OTU PF02338.19 RUS69853.1 - 2.2e-20 73.4 0.0 6.1e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.16 RUS69853.1 - 7.8e-07 28.9 6.4 7.8e-07 28.9 6.4 3.0 3 0 0 3 3 3 2 A20-like zinc finger Yos1 PF08571.10 RUS69854.1 - 4.3e-30 103.8 0.1 4.8e-30 103.7 0.1 1.0 1 0 0 1 1 1 1 Yos1-like LicD PF04991.13 RUS69855.1 - 2.8e-18 66.9 1.1 5.7e-13 49.5 0.6 2.4 1 1 1 2 2 2 2 LicD family C2 PF00168.30 RUS69856.1 - 4.6e-06 26.8 0.8 0.22 11.8 0.4 5.0 1 1 2 3 3 3 1 C2 domain DUF2476 PF10630.9 RUS69856.1 - 8e-06 26.2 0.0 2.1 8.4 0.0 4.2 1 1 3 4 4 4 1 Protein of unknown function (DUF2476) DUF4020 PF13212.6 RUS69856.1 - 1e-05 25.5 0.0 1 9.2 0.0 3.5 1 1 3 4 4 4 3 Domain of unknown function (DUF4020) Phage_tail_NK PF16532.5 RUS69856.1 - 0.00016 21.3 7.9 5.4 6.6 0.1 5.5 1 1 7 8 8 8 3 Sf6-type phage tail needle knob or tip of some Caudovirales TonB_C PF03544.14 RUS69856.1 - 0.0013 19.1 1.2 60 4.2 0.0 5.5 1 1 4 6 6 6 0 Gram-negative bacterial TonB protein C-terminal Methyltr_RsmB-F PF01189.17 RUS69856.1 - 0.0032 17.1 3.6 52 3.4 0.0 5.0 1 1 7 8 8 8 0 16S rRNA methyltransferase RsmB/F GramPos_pilinBB PF16569.5 RUS69856.1 - 0.0034 18.2 0.1 46 4.9 0.0 4.0 1 1 5 6 6 6 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain DUF1011 PF06237.12 RUS69857.1 - 5.9e-25 87.5 4.7 5.9e-25 87.5 4.7 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF1011) Nucleoside_tran PF01733.18 RUS69857.1 - 0.047 13.1 13.6 0.041 13.3 1.7 3.4 3 0 0 3 3 3 0 Nucleoside transporter FAM176 PF14851.6 RUS69857.1 - 0.38 10.4 5.0 0.081 12.6 0.8 2.1 2 0 0 2 2 2 0 FAM176 family DUF5383 PF17355.2 RUS69857.1 - 8 6.9 6.1 2.7 8.4 0.9 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5383) SSF PF00474.17 RUS69858.1 - 2.2e-38 132.2 25.8 2.9e-38 131.8 25.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family PHD PF00628.29 RUS69859.1 - 5.4e-29 99.8 51.7 8.8e-10 38.3 7.8 5.1 5 0 0 5 5 5 4 PHD-finger zf-HC5HC2H_2 PF13832.6 RUS69859.1 - 1.2e-27 96.2 28.3 3.8e-26 91.4 1.2 4.6 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RUS69859.1 - 1.8e-20 73.0 32.2 1e-16 61.0 0.6 5.0 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.6 RUS69859.1 - 2.4e-06 27.0 41.0 3.2e-06 26.6 7.1 6.7 6 1 0 6 6 6 3 PHD-finger Prok-RING_1 PF14446.6 RUS69859.1 - 0.0057 16.6 36.4 0.038 13.9 4.9 4.9 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 RUS69859.1 - 0.045 13.4 33.3 0.3 10.7 3.2 5.2 4 1 0 4 4 4 0 PHD/FYVE-zinc-finger like domain zf-UBP_var PF17807.1 RUS69859.1 - 0.22 11.3 8.9 0.99 9.2 3.5 3.1 3 0 0 3 3 3 0 Variant UBP zinc finger zf-RING_2 PF13639.6 RUS69859.1 - 2 8.8 52.4 1.3 9.4 9.3 4.7 4 1 0 4 4 4 0 Ring finger domain FANCL_C PF11793.8 RUS69859.1 - 4.1 7.6 37.5 0.62 10.3 5.5 4.6 4 0 0 4 4 4 0 FANCL C-terminal domain Usp PF00582.26 RUS69860.1 - 5.3e-16 59.4 0.0 1.2e-13 51.8 0.0 2.3 2 0 0 2 2 2 2 Universal stress protein family RSB_motif PF16294.5 RUS69861.1 - 0.021 15.1 0.9 0.043 14.1 0.9 1.5 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Tctex-1 PF03645.13 RUS69862.1 - 9.4e-27 93.3 0.6 1e-26 93.1 0.6 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF3361 PF11841.8 RUS69862.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Calponin PF00402.18 RUS69863.1 - 2.5e-13 49.4 6.3 3.9e-13 48.8 6.3 1.3 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 RUS69863.1 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS69863.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain AGS_C PF18134.1 RUS69863.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.5 1 1 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain RA PF00788.23 RUS69864.1 - 3e-08 34.2 0.0 6.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Snapin_Pallidin PF14712.6 RUS69864.1 - 0.64 10.5 9.7 0.92 10.0 7.4 2.6 1 1 0 1 1 1 0 Snapin/Pallidin Tho2 PF11262.8 RUS69864.1 - 0.85 8.8 4.4 1.5 8.0 4.4 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DCX PF03607.17 RUS69865.1 - 0.00019 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Doublecortin DCX PF03607.17 RUS69866.1 - 2.7e-13 49.8 0.0 3.9e-06 26.9 0.0 5.4 5 0 0 5 5 5 2 Doublecortin Ricin_B_lectin PF00652.22 RUS69866.1 - 2.2e-07 31.2 0.1 0.12 12.6 0.1 3.6 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain KHA PF11834.8 RUS69866.1 - 2.7e-07 30.6 0.0 1 9.5 0.0 4.7 4 0 0 4 4 4 3 KHA, dimerisation domain of potassium ion channel Rx_N PF18052.1 RUS69866.1 - 0.032 14.5 0.8 0.12 12.6 0.8 2.0 1 0 0 1 1 1 0 Rx N-terminal domain Arc_PepC_II PF06847.11 RUS69866.1 - 0.078 13.5 0.0 0.45 11.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II PEP-utilisers_N PF05524.13 RUS69866.1 - 0.093 12.9 2.8 0.092 12.9 0.5 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DNA_primase_lrg PF04104.14 RUS69866.1 - 0.97 8.8 4.3 0.31 10.4 0.2 2.1 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Ric8 PF10165.9 RUS69867.1 - 2.3e-54 185.2 2.2 2.7e-54 184.9 2.2 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Clavanin PF05452.11 RUS69867.1 - 0.064 13.5 0.3 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Clavanin A_deamin PF02137.18 RUS69869.1 - 1.3e-102 343.6 0.0 1.9e-102 343.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 RUS69869.1 - 6.6e-11 42.8 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif z-alpha PF02295.17 RUS69869.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain Patatin PF01734.22 RUS69869.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Patatin-like phospholipase DUF3915 PF13054.6 RUS69869.1 - 0.44 10.5 2.5 1.1 9.3 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sugar_tr PF00083.24 RUS69871.1 - 2.3e-22 79.5 3.2 3e-22 79.1 3.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS69871.1 - 2.3e-07 30.1 36.7 1.6e-05 24.0 15.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MAJIN PF15077.6 RUS69873.1 - 2.3 7.9 13.0 5 6.8 13.0 1.6 1 0 0 1 1 1 0 Membrane-anchored junction protein 5_3_exonuc_N PF02739.16 RUS69874.1 - 1.3e-26 93.4 0.3 2.9e-26 92.3 0.3 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 RUS69874.1 - 8.3e-22 77.6 0.0 3.2e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UvrD_C PF13361.6 RUS69874.1 - 1.6e-12 47.5 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RF3_C PF16658.5 RUS69874.1 - 1.9e-09 37.4 0.1 4.4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DeoC PF01791.9 RUS69874.1 - 9.6e-07 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DeoC/LacD family aldolase UvrD_C_2 PF13538.6 RUS69874.1 - 0.00059 19.6 0.4 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DNA_pol_lambd_f PF10391.9 RUS69874.1 - 0.1 12.5 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FBPase_glpX PF03320.13 RUS69875.1 - 2.3e-130 434.0 10.7 2.6e-130 433.8 10.7 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded ADH_zinc_N PF00107.26 RUS69875.1 - 0.08 12.9 0.7 0.31 11.0 0.2 2.2 2 1 1 3 3 3 0 Zinc-binding dehydrogenase FtsK_gamma PF09397.10 RUS69876.1 - 2.7e-28 97.5 0.7 5.3e-28 96.6 0.7 1.5 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_SpoIIIE PF01580.18 RUS69876.1 - 6.5e-14 51.9 0.3 1.1e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Arabinose_Isome PF02610.15 RUS69876.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 L-arabinose isomerase DUF3387 PF11867.8 RUS69877.1 - 4.9e-130 433.7 14.3 5.9e-130 433.5 14.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) LPD3 PF18798.1 RUS69877.1 - 0.0097 16.1 2.5 0.026 14.8 2.5 1.8 1 1 0 1 1 1 1 Large polyvalent protein-associated domain 3 Glyco_hydro_44 PF12891.7 RUS69877.1 - 0.04 13.8 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Prenyltrans PF00432.21 RUS69878.1 - 9.3e-20 70.1 7.7 3.3e-09 36.3 0.1 3.1 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 RUS69878.1 - 0.042 12.9 0.1 0.69 9.0 0.1 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 RUS69878.1 - 0.12 11.5 0.0 6.9 5.7 0.0 2.1 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Methyltransf_25 PF13649.6 RUS69879.1 - 2.8e-14 53.6 0.1 1.4e-11 45.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS69879.1 - 1.2e-12 48.3 0.3 1e-11 45.3 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS69879.1 - 7e-11 42.1 0.0 2.3e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS69879.1 - 4.6e-06 26.6 0.0 0.00061 19.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 RUS69879.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 RUS69879.1 - 0.00021 22.0 0.1 0.0022 18.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Spermine_synth PF01564.17 RUS69879.1 - 0.00071 19.0 0.4 0.0019 17.7 0.1 1.8 2 0 0 2 2 2 1 Spermine/spermidine synthase domain MTS PF05175.14 RUS69879.1 - 0.0024 17.4 0.0 0.012 15.2 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase small domain Pox_MCEL PF03291.16 RUS69879.1 - 0.0071 15.5 0.0 0.13 11.4 0.0 2.6 3 0 0 3 3 3 1 mRNA capping enzyme Methyltransf_32 PF13679.6 RUS69879.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Endonuclease_NS PF01223.23 RUS69880.1 - 1.4e-36 126.4 0.0 2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DNase_II PF03265.15 RUS69881.1 - 3.8e-105 351.7 3.0 9.1e-105 350.5 3.0 1.5 1 1 0 1 1 1 1 Deoxyribonuclease II MAJIN PF15077.6 RUS69882.1 - 0.066 13.0 0.5 0.1 12.4 0.4 1.3 1 1 0 1 1 1 0 Membrane-anchored junction protein adh_short_C2 PF13561.6 RUS69883.1 - 1.4e-63 214.6 1.1 1.6e-63 214.4 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS69883.1 - 4.6e-49 166.5 1.7 5.5e-49 166.3 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS69883.1 - 5e-16 59.1 0.8 7.3e-16 58.6 0.8 1.2 1 0 0 1 1 1 1 KR domain ROK PF00480.20 RUS69883.1 - 0.0023 17.5 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 2 ROK family Pkinase PF00069.25 RUS69884.1 - 3e-74 249.7 0.1 3.9e-74 249.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 RUS69884.1 - 3.2e-43 145.7 0.2 6.3e-22 77.5 0.1 2.4 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.17 RUS69884.1 - 9.6e-41 139.8 0.0 1.5e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS69884.1 - 4.5e-09 36.0 0.0 9e-08 31.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RUS69884.1 - 5.8e-07 28.6 0.0 9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS69884.1 - 0.076 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CRAL_TRIO_2 PF13716.6 RUS69885.1 - 0.086 13.0 0.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain DUF5600 PF18150.1 RUS69885.1 - 0.1 13.2 0.6 4.3 8.0 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5600) DUF4116 PF13475.6 RUS69885.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) IFT57 PF10498.9 RUS69885.1 - 0.42 9.5 4.9 0.44 9.5 3.8 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Holin_BhlA PF10960.8 RUS69885.1 - 0.46 10.5 0.0 0.46 10.5 0.0 2.7 3 0 0 3 3 3 0 BhlA holin family MAM PF00629.23 RUS69887.1 - 4.3e-71 238.0 0.2 2e-44 151.3 0.0 2.0 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu Ank_2 PF12796.7 RUS69889.1 - 8.3e-38 128.8 0.0 1.8e-13 50.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69889.1 - 9.1e-31 105.8 0.1 3.6e-07 30.6 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS69889.1 - 5.3e-30 103.1 1.1 1.6e-09 37.8 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS69889.1 - 6.1e-26 89.7 0.2 1.4e-05 25.3 0.5 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RUS69889.1 - 4.5e-25 85.0 0.1 0.0005 20.3 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Pre-SET PF05033.16 RUS69889.1 - 7.9e-12 45.8 5.8 7.9e-12 45.8 5.8 3.2 3 0 0 3 3 3 1 Pre-SET motif Ig_mannosidase PF17753.1 RUS69889.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Ig-fold domain Nucleos_tra2_C PF07662.13 RUS69890.1 - 7.1e-74 248.1 1.9 7.1e-74 248.1 1.9 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS69890.1 - 8.9e-23 80.7 1.1 8.9e-23 80.7 1.1 4.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS69890.1 - 2.3e-06 27.8 8.1 2.3e-06 27.8 8.1 3.1 3 1 0 3 3 3 1 Nucleoside recognition DUF5500 PF17604.2 RUS69891.1 - 0.06 13.4 0.2 0.098 12.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5500) CDT1 PF08839.11 RUS69892.1 - 2.3e-52 177.8 1.9 7e-52 176.2 0.9 2.4 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RUS69892.1 - 7.1e-27 93.7 0.6 7.1e-27 93.7 0.6 2.6 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Nnf1 PF03980.14 RUS69892.1 - 0.18 12.2 3.7 0.39 11.1 1.6 2.6 2 1 0 2 2 2 0 Nnf1 FAD_SOX PF18371.1 RUS69892.1 - 1.9 8.9 4.0 53 4.2 0.6 3.2 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Occludin_ELL PF07303.13 RUS69892.1 - 3.9 8.3 9.6 1.8 9.4 4.5 2.8 2 1 0 2 2 2 0 Occludin homology domain EVE PF01878.18 RUS69893.1 - 4.3e-49 166.3 0.1 6.1e-49 165.8 0.1 1.2 1 0 0 1 1 1 1 EVE domain LRR_4 PF12799.7 RUS69894.1 - 7e-16 58.1 18.3 2.3e-06 27.8 1.6 4.9 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS69894.1 - 4.9e-10 39.0 9.2 3.9e-05 23.3 1.9 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 RUS69894.1 - 2.3e-06 27.2 0.2 3.9e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RUS69894.1 - 0.00091 19.5 13.6 11 7.0 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS69894.1 - 0.0093 15.9 7.8 3.4 8.0 0.2 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 RUS69896.1 - 3e-14 52.9 3.3 4.4e-14 52.4 2.4 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 RUS69896.1 - 2.2e-09 37.5 15.6 6.8e-08 32.7 1.8 4.0 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS69896.1 - 2.4e-06 27.2 15.6 5e-05 23.0 5.6 2.9 1 1 2 3 3 3 2 Leucine rich repeat PaREP1 PF05942.11 RUS69896.1 - 0.058 13.3 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family APOBEC4 PF18775.1 RUS69896.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 APOBEC4 LRR_6 PF13516.6 RUS69896.1 - 8.4 6.7 6.3 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat GP52 PF17468.2 RUS69897.1 - 0.0043 17.2 0.2 0.41 10.8 0.0 2.3 2 0 0 2 2 2 2 Phage gene product 52 HIT PF01230.23 RUS69898.1 - 1.8e-27 96.0 0.0 2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RUS69898.1 - 1.8e-19 70.3 0.0 2.2e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding COMM_domain PF07258.14 RUS69899.1 - 1.9e-20 72.8 0.8 3.9e-20 71.7 0.8 1.5 1 0 0 1 1 1 1 COMM domain PORR PF11955.8 RUS69899.1 - 0.019 13.9 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain GBP PF02263.19 RUS69899.1 - 0.04 13.2 0.4 0.054 12.7 0.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain HIT PF01230.23 RUS69900.1 - 3.9e-27 94.9 0.0 4.4e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RUS69900.1 - 1.3e-22 80.5 0.0 1.5e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3338 PF11819.8 RUS69902.1 - 1.3e-32 112.6 4.1 4.1e-32 111.0 4.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) SHE3 PF17078.5 RUS69902.1 - 0.18 11.5 3.4 3 7.5 0.3 2.7 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 BCAS2 PF05700.11 RUS69902.1 - 1.8 8.2 6.3 17 5.1 2.1 2.4 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) FliD_N PF02465.18 RUS69902.1 - 6.9 7.4 9.5 0.56 10.9 1.1 3.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus FERM_C PF09380.10 RUS69903.1 - 0.00018 21.8 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Herpes_capsid PF06112.11 RUS69903.1 - 0.0054 16.8 27.4 0.0056 16.8 27.4 1.1 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein DUF515 PF04415.12 RUS69903.1 - 0.04 12.3 25.4 0.043 12.2 25.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apt1 PF10351.9 RUS69903.1 - 0.93 8.3 17.2 0.9 8.3 17.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 RUS69903.1 - 1.1 10.0 11.3 1.3 9.7 11.3 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SPX PF03105.19 RUS69903.1 - 1.1 9.1 15.5 1.1 9.1 15.5 1.0 1 0 0 1 1 1 0 SPX domain Myco_arth_vir_N PF09610.10 RUS69904.1 - 0.09 12.9 1.6 0.46 10.6 1.6 2.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF5315 PF17242.2 RUS69906.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Nop25 PF09805.9 RUS69906.1 - 2.2 8.8 5.6 0.51 10.8 1.9 1.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) COX8 PF02285.15 RUS69906.1 - 3.3 7.6 5.1 1.7 8.6 0.2 3.1 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII AAA_5 PF07728.14 RUS69908.1 - 1.9e-104 345.4 0.0 1.2e-42 145.1 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS69908.1 - 3.8e-08 33.9 0.1 0.18 12.2 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_7 PF12775.7 RUS69908.1 - 1.7e-05 24.4 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 RUS69908.1 - 2e-05 24.6 0.0 0.0054 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 RUS69908.1 - 2.9e-05 23.9 0.2 4.1 7.3 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS69908.1 - 3.7e-05 24.0 0.0 0.15 12.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 RUS69908.1 - 0.00028 21.3 0.0 0.4 11.1 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 RUS69908.1 - 0.0012 18.2 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial TniB protein ABC_tran PF00005.27 RUS69908.1 - 0.0017 18.9 0.0 3.6 8.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter VWA_2 PF13519.6 RUS69908.1 - 0.0019 18.9 0.0 0.0066 17.1 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RUS69908.1 - 0.0047 17.2 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain CbbQ_C PF08406.10 RUS69908.1 - 0.0056 16.9 0.1 1.8 8.9 0.0 2.6 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal Mg_chelatase PF01078.21 RUS69908.1 - 0.0075 15.7 0.1 7.1 5.9 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 RUS69908.1 - 0.0089 15.7 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_2 PF07724.14 RUS69908.1 - 0.009 16.1 0.1 8.4 6.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 RUS69908.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 RUS69908.1 - 0.016 14.3 0.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 RUS69908.1 - 0.042 14.2 0.0 0.5 10.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 RUS69908.1 - 0.097 12.7 0.0 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 RUS69908.1 - 0.14 12.4 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_18 PF00704.28 RUS69909.1 - 9.7e-54 183.2 0.0 1.6e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 RUS69909.1 - 1.3e-07 31.6 0.2 2.2e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Fibrinogen_C PF00147.18 RUS69910.1 - 4.9e-55 186.7 1.8 7.4e-55 186.1 1.8 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TSC22 PF01166.18 RUS69911.1 - 1.2e-22 79.9 1.3 1.2e-22 79.9 1.3 3.5 4 0 0 4 4 4 1 TSC-22/dip/bun family Shugoshin_N PF07558.11 RUS69911.1 - 0.0035 17.2 0.3 0.0076 16.1 0.3 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region YabA PF06156.13 RUS69911.1 - 0.053 14.2 0.5 0.053 14.2 0.5 3.1 3 0 0 3 3 3 0 Initiation control protein YabA REV1_C PF16727.5 RUS69912.1 - 0.091 13.2 0.0 0.93 9.9 0.0 2.7 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF5539 PF17693.1 RUS69912.1 - 4.1 7.0 7.6 32 4.1 4.9 2.6 1 1 0 2 2 2 0 Family of unknown function (DUF5539) DAO PF01266.24 RUS69913.1 - 0.058 13.0 0.1 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Atg14 PF10186.9 RUS69913.1 - 1.3 8.0 32.4 0.55 9.3 20.2 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 RUS69913.1 - 1.9 8.9 35.8 1 9.8 1.5 4.2 2 1 2 4 4 4 0 Centromere protein H (CENP-H) Lebercilin PF15619.6 RUS69913.1 - 3.6 7.2 40.5 1.5 8.4 4.2 3.8 2 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease ApoO PF09769.9 RUS69913.1 - 8.9 6.3 7.5 21 5.1 0.2 3.3 3 1 0 3 3 3 0 Apolipoprotein O AATF-Che1 PF13339.6 RUS69913.1 - 9.5 6.9 28.7 3.2 8.5 10.5 3.7 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor Y1_Tnp PF01797.16 RUS69914.1 - 0.097 12.8 0.6 15 5.7 0.2 2.5 2 0 0 2 2 2 0 Transposase IS200 like COMMD1_N PF17221.3 RUS69915.1 - 1.9e-39 134.1 0.6 3.9e-39 133.1 0.6 1.5 1 0 0 1 1 1 1 COMMD1 N-terminal domain COMM_domain PF07258.14 RUS69915.1 - 2.3e-15 56.4 3.2 2.4e-15 56.4 1.9 1.7 2 0 0 2 2 2 1 COMM domain RUN PF02759.19 RUS69915.1 - 0.077 12.9 0.8 0.12 12.3 0.8 1.3 1 0 0 1 1 1 0 RUN domain Cpn60_TCP1 PF00118.24 RUS69916.1 - 2.9e-158 527.5 13.8 3.3e-158 527.4 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 RUS69916.1 - 0.21 11.9 0.1 0.41 10.9 0.1 1.4 1 0 0 1 1 1 0 PcfK-like protein BAH PF01426.18 RUS69917.1 - 8.1e-32 109.6 0.1 9.8e-31 106.1 0.1 2.2 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 RUS69917.1 - 4.1e-12 46.7 0.8 1.4e-11 45.0 0.0 2.4 3 1 0 3 3 3 1 ELM2 domain GATA PF00320.27 RUS69917.1 - 4.1e-08 32.7 9.4 9.5e-08 31.5 9.4 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 RUS69917.1 - 1.9e-06 27.9 0.1 1.9e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RUS69917.1 - 0.0074 16.2 0.2 0.027 14.3 0.2 2.0 1 0 0 1 1 1 1 Myb DNA-binding like GIT1_C PF12205.8 RUS69917.1 - 0.075 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Peptidase_C54 PF03416.19 RUS69918.1 - 2.8e-45 154.9 0.1 4.2e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C54 Pkinase PF00069.25 RUS69919.1 - 1.7e-68 230.8 0.0 2.6e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69919.1 - 3.1e-38 131.6 0.0 4.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS69919.1 - 7.6e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FlgM PF04316.13 RUS69919.1 - 0.024 15.0 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM CBM_15 PF03426.14 RUS69919.1 - 0.11 12.1 3.1 0.19 11.3 3.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Mucin PF01456.17 RUS69919.1 - 0.85 9.6 13.2 1.6 8.7 13.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 RUS69919.1 - 1.7 7.1 17.0 2.2 6.7 17.0 1.1 1 0 0 1 1 1 0 Macoilin family NST1 PF13945.6 RUS69919.1 - 3.2 7.8 24.5 5.9 6.9 24.0 1.7 1 1 0 1 1 1 0 Salt tolerance down-regulator COesterase PF00135.28 RUS69920.1 - 5.6e-25 88.2 0.0 6.4e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Ank_5 PF13857.6 RUS69920.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) COesterase PF00135.28 RUS69921.1 - 1e-74 252.3 0.0 1.2e-74 252.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS69921.1 - 0.00017 21.5 0.8 0.0011 18.8 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS69921.1 - 0.00017 22.3 0.0 0.00021 21.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RUS69921.1 - 0.023 14.2 0.2 0.048 13.1 0.3 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family PhyH PF05721.13 RUS69922.1 - 4.3e-47 161.1 0.0 5.6e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 RUS69922.1 - 0.11 12.9 0.0 0.49 10.8 0.0 2.0 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase RVT_3 PF13456.6 RUS69924.1 - 0.0015 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Metallophos PF00149.28 RUS69926.1 - 1.5e-17 64.8 3.6 3e-17 63.8 3.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RUS69926.1 - 2.1e-11 44.5 0.0 6.4e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RUS69926.1 - 4.7e-09 36.7 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain p450 PF00067.22 RUS69927.1 - 1.5e-86 291.0 0.0 1.7e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PDEase_I PF00233.19 RUS69928.1 - 4.6e-68 229.5 7.4 6.9e-68 228.9 7.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MDD_C PF18376.1 RUS69928.1 - 0.069 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain HD PF01966.22 RUS69928.1 - 0.073 13.3 1.6 0.13 12.5 0.2 2.0 1 1 1 2 2 2 0 HD domain PQ-loop PF04193.14 RUS69929.1 - 1.3e-13 50.4 1.0 2.5e-13 49.6 1.0 1.5 1 0 0 1 1 1 1 PQ loop repeat UPRTase PF14681.6 RUS69930.1 - 2.1e-08 33.9 0.0 2.7e-08 33.5 0.0 1.2 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase SH3BGR PF04908.15 RUS69932.1 - 8.2e-25 86.9 0.1 8.2e-25 86.9 0.1 4.1 2 1 3 6 6 6 1 SH3-binding, glutamic acid-rich protein Nuc_deoxyri_tr2 PF15891.5 RUS69932.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like Lebercilin PF15619.6 RUS69933.1 - 1e-50 172.1 43.3 1e-50 172.1 43.3 3.9 2 1 2 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 RUS69933.1 - 1.7 9.2 8.3 2.2 8.8 1.8 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CHD5 PF04420.14 RUS69935.1 - 1.6e-29 102.8 0.0 1.7e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF2207 PF09972.9 RUS69935.1 - 0.16 10.7 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2976 PF11190.8 RUS69935.1 - 0.25 11.2 0.2 0.25 11.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3464 PF11947.8 RUS69935.1 - 0.57 9.9 4.0 0.6 9.9 3.2 1.7 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 RasGEF PF00617.19 RUS69937.1 - 2.2e-51 174.6 0.0 6e-51 173.2 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RUS69937.1 - 1.2e-12 47.9 0.9 1e-11 45.0 0.9 2.4 1 1 0 1 1 1 1 RasGEF N-terminal motif PDZ PF00595.24 RUS69937.1 - 5e-11 42.8 0.0 1.8e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain RA PF00788.23 RUS69937.1 - 3.4e-08 34.0 0.1 9.8e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_6 PF17820.1 RUS69937.1 - 3.9e-08 33.0 0.0 1.7e-07 31.0 0.0 2.2 1 1 1 2 2 2 1 PDZ domain cNMP_binding PF00027.29 RUS69937.1 - 0.00012 22.0 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 RUS69937.1 - 0.00036 20.8 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Cupin_3 PF05899.12 RUS69937.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pkinase PF00069.25 RUS69938.1 - 6.3e-17 61.8 0.2 7.5e-17 61.6 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS69938.1 - 2.4e-12 46.7 0.1 2.8e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase SCAN PF02023.17 RUS69939.1 - 2.6e-13 49.6 0.7 8.1e-13 48.0 0.1 2.2 2 0 0 2 2 2 1 SCAN domain zf-CCHC PF00098.23 RUS69939.1 - 8.7e-06 25.6 13.0 0.00076 19.5 3.0 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 RUS69939.1 - 0.0079 15.9 10.5 0.094 12.5 1.5 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS69939.1 - 0.026 14.3 5.8 0.026 14.3 5.8 2.2 2 0 0 2 2 2 0 Zinc knuckle 5_nucleotid PF05761.14 RUS69939.1 - 4.8 6.0 6.6 10 4.9 6.6 1.6 1 0 0 1 1 1 0 5' nucleotidase family RVT_1 PF00078.27 RUS69941.1 - 2.6e-35 121.9 0.4 1.5e-25 90.0 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Borrelia_lipo_1 PF05714.11 RUS69941.1 - 0.11 12.2 11.1 0.48 10.2 1.5 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Imm7 PF15585.6 RUS69941.1 - 0.16 12.3 1.6 15 5.8 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 7 DUF520 PF04461.13 RUS69941.1 - 0.38 10.8 5.6 11 6.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF520) DSL PF01414.19 RUS69941.1 - 2 8.7 14.7 4.2 7.7 14.7 1.5 1 0 0 1 1 1 0 Delta serrate ligand Peptidase_A17 PF05380.13 RUS69942.1 - 3.2e-47 160.6 0.0 5.1e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase ELFV_dehydrog PF00208.21 RUS69944.1 - 1.5e-80 270.4 5.5 1.8e-80 270.2 5.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 RUS69944.1 - 9.2e-21 74.1 0.2 2.1e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 RUS69944.1 - 0.028 14.5 0.4 0.06 13.4 0.4 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NRDD PF13597.6 RUS69944.1 - 0.047 12.5 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase adh_short PF00106.25 RUS69945.1 - 4.9e-38 130.5 0.2 5.5e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS69945.1 - 2e-26 93.0 0.0 2.3e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS69945.1 - 2e-08 34.3 0.1 2.3e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RUS69945.1 - 3.3e-05 23.9 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RUS69945.1 - 0.00038 20.0 1.3 0.001 18.6 1.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 RUS69945.1 - 0.0035 17.3 0.0 0.0087 16.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase YjeF_N PF03853.15 RUS69945.1 - 0.027 14.3 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus TrkA_N PF02254.18 RUS69945.1 - 0.039 14.2 0.1 0.091 13.0 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain DUF1776 PF08643.10 RUS69945.1 - 0.049 13.0 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cpn60_TCP1 PF00118.24 RUS69946.1 - 3.2e-94 316.3 20.7 6.1e-94 315.4 20.7 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lar_N PF09861.9 RUS69946.1 - 0.0074 15.5 0.1 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Lactate racemase N-terminal domain MukE PF04288.13 RUS69946.1 - 0.16 10.9 0.2 0.29 10.0 0.2 1.3 1 0 0 1 1 1 0 MukE-like family DUF3281 PF11685.8 RUS69947.1 - 2.3e-10 40.3 1.0 3.7e-10 39.6 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3281) PGM_PMM_I PF02878.16 RUS69947.1 - 2e-07 30.8 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNB PF00773.19 RUS69947.1 - 3.1e-06 26.8 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain DNA_topoisoIV PF00521.20 RUS69948.1 - 9.4e-95 318.0 0.1 1.2e-94 317.6 0.1 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 RUS69948.1 - 1e-41 140.1 10.4 1.4e-14 53.3 0.2 3.6 4 0 0 4 4 4 3 DNA gyrase C-terminal domain, beta-propeller DUF2291 PF10054.9 RUS69948.1 - 0.0025 17.6 0.8 0.9 9.2 0.8 2.4 2 0 0 2 2 2 2 Predicted periplasmic lipoprotein (DUF2291) SBD PF17882.1 RUS69948.1 - 0.17 11.7 0.9 1.3 8.9 0.4 2.2 1 1 1 2 2 2 0 OAA-family lectin sugar binding domain Pyr_redox_2 PF07992.14 RUS69949.1 - 1.5e-67 227.9 6.2 1.9e-67 227.6 6.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RUS69949.1 - 4.2e-31 107.4 1.1 4.9e-30 104.0 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RUS69949.1 - 2.4e-17 63.2 5.6 5.4e-14 52.5 1.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS69949.1 - 1.7e-10 40.7 2.1 4.6e-09 36.0 2.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS69949.1 - 6.2e-08 32.1 7.5 1.1e-06 28.0 0.9 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 RUS69949.1 - 2.3e-07 30.5 0.5 2.3e-07 30.5 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RUS69949.1 - 3.8e-07 30.3 7.1 0.00027 21.1 0.4 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS69949.1 - 1.2e-05 24.7 4.3 0.00039 19.6 0.4 3.1 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 RUS69949.1 - 0.00012 21.4 3.0 0.014 14.7 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 RUS69949.1 - 0.00067 19.6 2.9 0.02 14.8 0.5 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 RUS69949.1 - 0.001 18.2 0.2 0.27 10.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 RUS69949.1 - 0.0011 18.2 1.5 0.77 8.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 RUS69949.1 - 0.0067 15.2 4.7 0.045 12.5 0.2 2.8 2 1 1 3 3 3 1 HI0933-like protein DAO PF01266.24 RUS69949.1 - 0.011 15.3 8.0 0.77 9.3 0.4 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase XdhC_C PF13478.6 RUS69949.1 - 0.017 15.7 0.2 1.1 9.7 0.0 2.7 2 1 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 RUS69949.1 - 0.038 13.4 0.5 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RUS69949.1 - 0.046 14.2 0.6 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 RUS69949.1 - 2.2 7.8 6.6 0.13 11.8 0.5 2.1 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH_E1_M PF17831.1 RUS69950.1 - 1.2e-33 116.6 0.5 2.5e-33 115.5 0.0 1.6 2 0 0 2 2 2 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 RUS69950.1 - 6.6e-16 58.2 0.0 7.4e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain PS_Dcarbxylase PF02666.15 RUS69951.1 - 2.1e-57 193.9 0.0 2.6e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PCRF PF03462.18 RUS69952.1 - 2.1e-66 223.5 1.0 3.3e-66 222.9 0.1 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 RUS69952.1 - 6.3e-43 145.4 1.4 6.3e-43 145.4 1.4 2.1 2 0 0 2 2 2 1 RF-1 domain TSSC4 PF15264.6 RUS69952.1 - 0.036 14.3 0.8 0.11 12.8 0.8 1.7 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 3Beta_HSD PF01073.19 RUS69953.1 - 2.7e-07 29.9 0.0 4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS69953.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RUS69953.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 RUS69953.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RUS69953.1 - 0.054 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GW PF13457.6 RUS69953.1 - 0.11 13.1 0.6 0.11 13.1 0.6 1.9 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain VWA_N2 PF16164.5 RUS69953.1 - 0.37 10.9 4.3 1.1 9.4 4.3 1.9 1 0 0 1 1 1 0 VWA N-terminal 3Beta_HSD PF01073.19 RUS69954.1 - 4.8e-32 111.1 0.0 6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS69954.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RUS69954.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F-box-like PF12937.7 RUS69956.1 - 5.6e-10 39.0 1.4 8.9e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS69956.1 - 4.4e-06 26.4 0.9 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 RUS69956.1 - 0.00016 21.9 21.4 0.97 9.9 0.4 6.7 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) YL1 PF05764.13 RUS69956.1 - 0.032 14.4 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein LRR_6 PF13516.6 RUS69956.1 - 1.7 8.9 14.0 37 4.7 0.0 7.3 10 0 0 10 10 10 0 Leucine Rich repeat Innexin PF00876.18 RUS69957.1 - 2.8e-84 283.4 14.6 3.2e-84 283.2 14.6 1.0 1 0 0 1 1 1 1 Innexin IP_trans PF02121.18 RUS69958.1 - 1.9e-86 289.7 0.0 2.3e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Presenilin PF01080.17 RUS69959.1 - 4.2 6.0 4.5 6.1 5.5 4.5 1.3 1 0 0 1 1 1 0 Presenilin GST_N_4 PF17172.4 RUS69960.1 - 1.3e-23 83.6 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS69960.1 - 1.9e-18 66.0 0.0 3.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS69960.1 - 3.3e-08 33.4 0.0 6.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS69960.1 - 0.027 14.9 0.0 0.15 12.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ThuA PF06283.11 RUS69960.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Trehalose utilisation GST_N_2 PF13409.6 RUS69960.1 - 0.13 12.6 0.2 3.2 8.1 0.2 2.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UBA_4 PF14555.6 RUS69961.1 - 2.7e-10 39.9 0.1 6.4e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 RUS69961.1 - 3.2e-09 36.9 0.1 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 RUS69961.1 - 0.00063 19.9 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like AAA_23 PF13476.6 RUS69961.1 - 0.13 12.8 7.0 0.18 12.2 7.0 1.4 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 RUS69961.1 - 1.3 7.2 8.3 1.7 6.8 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 RUS69961.1 - 1.5 8.2 11.1 2.5 7.4 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) rRNA_processing PF08524.11 RUS69961.1 - 5.8 6.9 23.9 8.7 6.4 23.9 1.2 1 0 0 1 1 1 0 rRNA processing SOCS_box PF07525.16 RUS69962.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 3.5 4 0 0 4 4 4 1 SOCS box Ank_2 PF12796.7 RUS69962.1 - 0.016 15.7 0.0 0.045 14.3 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS69962.1 - 0.029 15.0 0.1 0.9 10.2 0.0 2.8 3 1 0 3 3 3 0 Ankyrin repeats (many copies) HtrL_YibB PF09612.10 RUS69963.1 - 1.3e-16 61.0 0.0 5.1e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Integrin_alpha2 PF08441.12 RUS69964.1 - 1.6e-49 169.1 3.2 2.2e-49 168.6 3.2 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 RUS69964.1 - 4.3e-16 58.7 8.2 3.3e-08 33.5 1.2 2.8 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 RUS69964.1 - 7.2e-07 29.7 12.4 1.3e-05 25.6 3.3 3.3 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 RUS69964.1 - 0.046 13.7 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Ribosomal_L37ae PF01780.19 RUS69965.1 - 6.2e-40 135.2 10.0 7.3e-40 135.0 10.0 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Elf1 PF05129.13 RUS69965.1 - 0.006 16.6 0.5 0.0096 16.0 0.5 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 RUS69965.1 - 0.012 16.0 2.2 0.015 15.6 0.8 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 RUS69965.1 - 0.018 15.0 4.2 0.031 14.2 4.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Toxin_38 PF14866.6 RUS69965.1 - 0.023 15.0 2.2 0.042 14.1 2.2 1.4 1 0 0 1 1 1 0 Potassium channel toxin Rep_fac-A_C PF08646.10 RUS69965.1 - 0.024 14.4 0.9 0.032 14.0 0.9 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain A2L_zn_ribbon PF08792.10 RUS69965.1 - 0.03 14.0 2.3 0.045 13.5 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf_UBZ PF18439.1 RUS69965.1 - 0.031 13.9 2.9 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RING_13 PF17977.1 RUS69965.1 - 0.032 14.4 4.1 0.06 13.5 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.14 RUS69965.1 - 0.036 13.9 2.4 0.069 13.0 0.2 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1451 PF07295.11 RUS69965.1 - 0.056 13.5 1.8 0.096 12.7 1.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_ribbon_SprT PF17283.2 RUS69965.1 - 0.056 13.4 3.2 0.16 11.9 3.2 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 RUS69966.1 - 3.2e-31 107.7 15.0 2.1e-26 92.2 0.4 3.5 3 1 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RUS69966.1 - 3.5e-08 33.5 5.0 3.5e-08 33.5 5.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS69966.1 - 1.8e-07 31.3 2.0 1.8e-07 31.3 2.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type OrsD PF12013.8 RUS69966.1 - 0.06 13.8 8.2 0.64 10.5 4.9 3.2 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 RUS69966.1 - 0.14 13.1 15.1 0.18 12.7 0.2 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-LYAR PF08790.11 RUS69966.1 - 0.27 11.2 2.5 21 5.1 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-3CxxC_2 PF17180.4 RUS69966.1 - 0.29 11.9 8.7 0.06 14.1 4.1 2.4 2 1 0 2 2 2 0 Zinc-binding domain TSP_C PF05735.12 RUS69967.1 - 1.5e-96 322.0 0.3 1.9e-96 321.7 0.3 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 RUS69967.1 - 1.6e-42 142.8 129.4 1.1e-10 41.0 14.1 8.2 7 2 1 8 8 8 7 Thrombospondin type 3 repeat Cu-oxidase_4 PF02578.15 RUS69969.1 - 2.5e-50 171.2 0.0 3.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase AMP-binding PF00501.28 RUS69970.1 - 1.6e-63 214.7 0.0 3.7e-63 213.6 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS69970.1 - 3.3e-06 28.0 0.0 7.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Trypsin PF00089.26 RUS69971.1 - 2.3e-50 171.5 0.0 1.3e-49 169.0 0.0 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS69971.1 - 1.3e-05 26.1 0.0 3.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RUS69971.1 - 0.13 12.6 0.0 5.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) zf-C2H2 PF00096.26 RUS69973.1 - 2.2e-32 109.7 48.9 1.2e-06 28.6 1.3 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS69973.1 - 1.9e-29 99.8 43.4 3e-05 24.5 0.7 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS69973.1 - 1e-25 89.0 48.2 1.8e-07 31.3 1.9 7.8 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS69973.1 - 3.7e-18 65.3 28.2 3.7e-05 23.9 1.3 7.2 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS69973.1 - 1.5e-15 56.7 42.5 3.3e-05 23.7 0.5 8.2 8 1 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 RUS69973.1 - 3.7e-13 49.4 30.3 0.00034 20.9 1.1 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RUS69973.1 - 6.2e-05 23.2 20.6 0.07 13.4 1.8 3.2 1 1 2 3 3 3 3 C2H2-type zinc ribbon C1_1 PF00130.22 RUS69973.1 - 0.0001 22.1 16.9 0.44 10.5 0.3 4.4 1 1 3 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 RUS69973.1 - 0.0027 18.0 34.2 0.2 12.0 0.8 6.1 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) BolA PF01722.18 RUS69973.1 - 0.0058 16.9 3.0 6.7 7.1 0.2 3.6 2 1 1 3 3 3 1 BolA-like protein zinc_ribbon_15 PF17032.5 RUS69973.1 - 0.0061 17.3 24.2 0.41 11.4 1.1 3.6 1 1 3 4 4 4 3 zinc-ribbon family zf-FCS PF06467.14 RUS69973.1 - 0.012 15.5 20.3 0.79 9.7 0.1 5.4 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_9 PF16293.5 RUS69973.1 - 0.015 15.2 13.2 0.068 13.0 0.3 5.0 4 1 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 RUS69973.1 - 0.018 15.3 4.9 0.018 15.3 4.9 4.8 2 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 RUS69973.1 - 0.051 13.5 0.4 0.051 13.5 0.4 5.8 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Vps36-NZF-N PF16988.5 RUS69973.1 - 0.12 11.8 11.5 0.46 9.9 0.2 4.1 2 1 2 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PALB2_WD40 PF16756.5 RUS69973.1 - 0.17 10.8 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain zf-C2H2_11 PF16622.5 RUS69973.1 - 0.17 11.7 26.5 3.4 7.5 0.1 7.0 7 1 0 7 7 7 0 zinc-finger C2H2-type zf-AN1 PF01428.16 RUS69973.1 - 0.23 11.7 27.0 0.44 10.8 0.2 6.1 5 1 1 6 6 6 0 AN1-like Zinc finger ZZ PF00569.17 RUS69973.1 - 0.23 11.3 0.1 0.23 11.3 0.1 6.1 6 1 1 7 7 6 0 Zinc finger, ZZ type zf_UBZ PF18439.1 RUS69973.1 - 0.27 10.9 25.3 0.41 10.3 0.1 6.5 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger C1_2 PF03107.16 RUS69973.1 - 0.83 10.0 37.9 2.6 8.4 4.9 6.6 2 1 2 4 4 3 0 C1 domain Zn-ribbon_8 PF09723.10 RUS69973.1 - 1.8 8.7 32.1 1.2 9.3 2.8 5.4 4 1 2 6 6 6 0 Zinc ribbon domain zf-C2HE PF16278.5 RUS69973.1 - 2.4 8.6 25.9 3.5 8.2 0.2 5.3 1 1 3 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 RUS69973.1 - 3.6 7.9 28.0 0.53 10.6 2.1 4.8 1 1 3 5 5 5 0 TFIIH C1-like domain zf_C2H2_ZHX PF18387.1 RUS69973.1 - 3.6 7.3 12.9 17 5.2 0.0 4.1 4 1 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain GvpL_GvpF PF06386.11 RUS69974.1 - 5.5 6.8 9.6 0.26 11.2 0.3 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF MFS_1 PF07690.16 RUS69975.1 - 6.1e-18 64.9 6.5 6.1e-18 64.9 6.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS69975.1 - 2e-08 33.5 0.3 2.2e-08 33.4 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RUS69975.1 - 0.00012 21.5 2.6 0.00017 21.0 2.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PKD_channel PF08016.12 RUS69976.1 - 4.2e-45 154.2 18.9 4.9e-45 154.0 18.9 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RUS69976.1 - 4.5e-11 42.5 19.9 6.1e-11 42.0 19.9 1.2 1 0 0 1 1 1 1 Ion transport protein EVC2_like PF12297.8 RUS69976.1 - 0.0057 15.4 2.8 0.0091 14.7 2.8 1.3 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein DUF4191 PF13829.6 RUS69976.1 - 2.6 7.3 6.2 1.9 7.8 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3810 PF12725.7 RUS69976.1 - 9.8 5.4 11.1 0.05 12.9 0.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) SapA PF02199.15 RUS69979.1 - 5.5e-06 26.6 1.7 47 4.4 0.0 5.1 5 0 0 5 5 5 0 Saposin A-type domain CARD PF00619.21 RUS69979.1 - 9.7e-05 22.3 1.0 2.4 8.2 0.0 3.1 1 1 3 4 4 4 4 Caspase recruitment domain Telomere_Sde2_2 PF13297.6 RUS69979.1 - 0.00012 21.6 4.2 18 5.0 0.1 4.9 3 1 2 5 5 5 0 Telomere stability C-terminal SCVP PF17619.2 RUS69979.1 - 0.00025 21.8 6.6 11 7.0 0.2 4.3 1 1 3 4 4 4 0 Secreted clade V proteins DUF3539 PF12058.8 RUS69979.1 - 0.038 14.1 1.4 9.6 6.4 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3539) DUF4905 PF16248.5 RUS69979.1 - 0.039 13.9 0.8 15 5.5 0.0 3.6 1 1 2 4 4 4 0 Domain of unknown function (DUF4905) AalphaY_MDB PF04611.12 RUS69979.1 - 0.039 14.0 1.7 4.3 7.4 0.1 2.3 1 1 1 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region EFG_II PF14492.6 RUS69979.1 - 0.071 13.2 2.0 16 5.7 0.1 3.0 1 1 3 4 4 4 0 Elongation Factor G, domain II DUF3677 PF12432.8 RUS69979.1 - 0.079 13.3 5.7 0.87 9.9 0.4 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3677) E1-N PF14463.6 RUS69979.1 - 0.096 12.5 0.0 15 5.4 0.0 2.6 1 1 1 3 3 3 0 E1 N-terminal domain HAD_2 PF13419.6 RUS69979.1 - 0.1 12.7 0.5 0.13 12.4 0.5 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ERF PF04404.12 RUS69979.1 - 0.11 12.4 3.4 3 7.7 0.3 2.0 1 1 1 2 2 2 0 ERF superfamily DUF2023 PF09633.10 RUS69979.1 - 0.25 11.5 1.7 14 5.9 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2023) Ornatin PF02088.15 RUS69979.1 - 0.29 10.9 7.4 51 3.8 0.0 4.3 5 0 0 5 5 5 0 Ornatin Arm-DNA-bind_2 PF12167.8 RUS69979.1 - 0.44 10.5 2.4 30 4.6 0.1 3.0 1 1 3 4 4 4 0 Arm DNA-binding domain Ribos_L4_asso_C PF14374.6 RUS69979.1 - 0.45 10.6 12.0 23 5.1 0.2 3.9 1 1 3 4 4 4 0 60S ribosomal protein L4 C-terminal domain Rbsn PF11464.8 RUS69979.1 - 0.69 9.7 6.6 29 4.5 0.1 3.8 4 0 0 4 4 4 0 Rabenosyn Rab binding domain Nucleos_tra2_N PF01773.20 RUS69981.1 - 8.4e-21 74.4 1.2 3.2e-20 72.5 1.2 2.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS69981.1 - 0.024 14.9 5.2 0.024 14.9 5.2 2.4 2 1 0 2 2 2 0 Nucleoside recognition Homeodomain PF00046.29 RUS69982.1 - 8.2e-24 83.2 5.8 1.4e-23 82.4 5.8 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS69982.1 - 6.3e-08 32.2 3.7 0.00042 20.1 1.6 2.6 2 0 0 2 2 2 2 OAR domain Homeobox_KN PF05920.11 RUS69982.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF4383 PF14325.6 RUS69984.1 - 0.00016 21.9 0.3 0.00022 21.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) CD20 PF04103.15 RUS69984.1 - 0.0037 17.4 2.0 0.0052 16.9 2.0 1.2 1 0 0 1 1 1 1 CD20-like family Pox_A14 PF05767.12 RUS69984.1 - 0.027 14.6 2.6 0.044 13.9 2.6 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3784 PF12650.7 RUS69984.1 - 0.062 13.5 2.7 0.11 12.7 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) SK_channel PF03530.14 RUS69984.1 - 0.22 11.5 2.0 0.35 10.9 2.0 1.2 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Phage_holin_3_6 PF07332.11 RUS69984.1 - 0.26 11.4 3.2 0.38 10.8 3.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EphA2_TM PF14575.6 RUS69984.1 - 0.29 12.1 2.1 1.9 9.5 0.0 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WSC PF01822.19 RUS69985.1 - 0.019 15.2 0.0 0.039 14.1 0.0 1.6 1 1 0 1 1 1 0 WSC domain DUF1647 PF07801.11 RUS69986.1 - 2.9e-12 46.5 0.2 4.7e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) RVT_1 PF00078.27 RUS69987.1 - 1.5e-09 37.7 0.1 1.9e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OmpA_membrane PF01389.17 RUS69988.1 - 0.031 14.0 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 OmpA-like transmembrane domain EGF_CA PF07645.15 RUS69990.1 - 0 1092.8 720.4 8.1e-09 35.5 10.9 45.2 44 1 1 45 45 45 45 Calcium-binding EGF domain cEGF PF12662.7 RUS69990.1 - 4.4e-220 710.7 461.4 2.9e-07 30.3 3.3 45.7 45 0 0 45 45 45 45 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS69990.1 - 3.5e-195 631.9 710.1 9.8e-07 28.9 9.9 45.6 42 3 2 45 45 45 45 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RUS69990.1 - 1.4e-70 231.8 447.3 0.0033 18.0 2.9 46.9 45 0 0 45 45 45 41 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 RUS69990.1 - 9.5e-60 198.7 599.4 1.1e-06 28.8 4.0 45.9 41 3 4 45 45 45 37 Pvs28 EGF domain EGF_3 PF12947.7 RUS69990.1 - 4.1e-46 154.9 634.1 0.0078 16.4 5.4 49.3 45 5 1 46 46 46 40 EGF domain VWA PF00092.28 RUS69990.1 - 8.9e-31 107.5 2.0 1.2e-30 107.0 2.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 RUS69990.1 - 1e-30 105.6 710.1 0.015 15.6 4.2 46.3 45 0 0 45 45 45 39 EGF-like domain VWA_2 PF13519.6 RUS69990.1 - 7.1e-10 39.5 0.1 1.1e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS69990.1 - 1.9e-06 27.9 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SSF PF00474.17 RUS69991.1 - 1.1e-08 34.4 1.3 1.1e-08 34.4 1.3 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family KicB PF03882.14 RUS69992.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 MukF winged-helix domain CwfJ_C_1 PF04677.15 RUS69993.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.22 RUS69994.1 - 3.9e-12 45.8 0.0 6.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS69994.1 - 2.9e-05 23.6 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS69994.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RSRP PF17069.5 RUS69994.1 - 2.4 7.7 40.7 3.6 7.1 40.7 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RabGAP-TBC PF00566.18 RUS69995.1 - 2.9e-12 46.7 1.7 6.8e-12 45.5 1.7 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 RUS69995.1 - 0.021 15.7 7.7 42 5.2 4.6 4.4 3 1 0 3 3 3 0 WD domain, G-beta repeat WD40_like PF17005.5 RUS69995.1 - 0.079 12.3 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Acyl-ACP_TE PF01643.17 RUS69996.1 - 8.2e-11 41.7 0.0 2.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS69996.1 - 0.00066 20.2 0.1 0.005 17.3 0.1 2.2 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF4097 PF13349.6 RUS69997.1 - 1.5e-05 24.5 0.1 0.00024 20.6 0.1 2.1 1 1 0 1 1 1 1 Putative adhesin Dehydratase_SU PF02287.15 RUS69997.1 - 0.016 15.3 0.1 42 4.2 0.0 4.1 1 1 3 5 5 5 0 Dehydratase small subunit PliI PF16743.5 RUS69997.1 - 0.046 13.5 3.0 4.2 7.1 0.1 3.3 1 1 1 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme Pentapeptide_3 PF13576.6 RUS69997.1 - 0.1 12.8 0.2 32 4.8 0.0 3.4 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) GLTT PF01744.20 RUS69998.1 - 1.6e-06 27.7 45.8 0.0026 17.5 11.8 6.4 4 2 3 7 7 7 7 GLTT repeat (6 copies) A_deamin PF02137.18 RUS69999.1 - 1.9e-92 310.3 0.0 2.6e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 RUS69999.1 - 5.2e-22 78.3 0.0 4.7e-12 46.4 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 RUS69999.1 - 0.061 13.6 0.1 16 5.8 0.0 2.9 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 2OG-FeII_Oxy_3 PF13640.6 RUS70000.1 - 2e-17 63.8 0.0 3.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RUS70000.1 - 2.8e-10 40.7 0.0 6.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 RUS70000.1 - 6.4e-10 39.0 13.6 6.4e-10 39.0 13.6 1.8 2 0 0 2 2 2 1 MYND finger zf-RING_2 PF13639.6 RUS70001.1 - 3.7e-08 33.6 8.9 8.4e-08 32.4 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS70001.1 - 6.7e-08 32.3 9.3 1.4e-07 31.3 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS70001.1 - 6.9e-08 32.2 8.8 1.4e-07 31.2 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS70001.1 - 3.7e-07 29.9 5.3 6.5e-07 29.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS70001.1 - 6.8e-06 26.0 3.5 6.8e-06 26.0 3.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS70001.1 - 2.5e-05 24.5 6.6 0.0001 22.5 6.6 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS70001.1 - 5.5e-05 23.0 9.9 0.0001 22.2 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RUS70001.1 - 0.0039 16.9 5.3 0.7 9.7 5.8 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 RUS70001.1 - 0.013 15.6 4.5 0.036 14.2 4.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 RUS70001.1 - 0.015 15.1 8.5 0.034 14.0 8.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RUS70001.1 - 0.024 14.7 2.5 0.073 13.1 2.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RUS70001.1 - 0.082 12.7 7.1 0.16 11.8 7.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RUS70001.1 - 0.1 12.8 10.0 0.24 11.6 10.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 RUS70001.1 - 0.39 10.4 7.2 0.89 9.3 7.2 1.6 1 0 0 1 1 1 0 P-11 zinc finger IBR PF01485.21 RUS70001.1 - 0.66 10.3 5.3 2.2 8.6 5.3 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Baculo_IE-1 PF05290.11 RUS70001.1 - 1.9 8.5 7.6 4.8 7.1 7.6 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SWIM PF04434.17 RUS70003.1 - 0.00054 19.6 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger HEPN_Swt1 PF18731.1 RUS70003.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Swt1-like HEPN TCTP PF00838.17 RUS70004.1 - 2.6e-42 145.0 0.5 3.1e-42 144.7 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Rhomboid PF01694.22 RUS70005.1 - 3.3e-26 92.1 13.1 6.6e-26 91.1 13.1 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1230 PF06799.11 RUS70005.1 - 0.66 10.1 3.4 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Abhydrolase_3 PF07859.13 RUS70006.1 - 1.6e-54 185.0 0.0 7.4e-43 146.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 RUS70006.1 - 7.4e-06 25.1 0.0 5.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS70006.1 - 0.00065 19.2 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS70006.1 - 0.0015 17.4 0.0 0.0042 16.0 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase UCH_C PF18031.1 RUS70007.1 - 0.025 14.5 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases FliS PF02561.14 RUS70007.1 - 0.08 13.2 1.6 1.7 8.9 0.3 3.1 2 1 0 2 2 2 0 Flagellar protein FliS EF-hand_14 PF17959.1 RUS70007.1 - 0.21 12.0 0.9 3.9 7.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DUF1992 PF09350.10 RUS70008.1 - 1.7e-23 82.5 0.0 6.2e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 RUS70008.1 - 3.9e-11 42.9 0.2 3.9e-11 42.9 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain zf-C2H2 PF00096.26 RUS70009.1 - 3.5e-11 42.9 99.6 0.0019 18.6 0.3 10.5 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS70009.1 - 1.6e-09 37.7 88.3 0.00011 22.5 0.7 10.8 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS70009.1 - 9.3e-09 35.4 92.1 0.036 14.9 5.8 10.3 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS70009.1 - 0.0025 18.1 46.9 0.39 11.1 3.5 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS70009.1 - 0.0066 16.2 0.4 0.0066 16.2 0.4 8.4 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS70009.1 - 0.01 15.8 0.9 0.01 15.8 0.9 8.4 9 0 0 9 9 9 0 C2H2-type zinc finger AT_hook PF02178.19 RUS70009.1 - 1.3 9.1 7.3 5.5 7.2 7.3 2.1 1 0 0 1 1 1 0 AT hook motif Mtc PF03820.17 RUS70010.1 - 1e-135 451.8 1.5 1.1e-135 451.7 1.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Smg4_UPF3 PF03467.15 RUS70010.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family ALMS_motif PF15309.6 RUS70011.1 - 8.1e-29 100.8 17.0 8.1e-29 100.8 17.0 4.9 3 2 1 4 4 4 1 ALMS motif Rota_NSP4 PF01452.16 RUS70011.1 - 0.039 13.6 0.2 0.09 12.4 0.2 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein Arf PF00025.21 RUS70014.1 - 2.3e-48 163.9 0.0 2.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS70014.1 - 2.3e-16 59.8 0.0 2.7e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70014.1 - 8.9e-16 58.2 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS70014.1 - 2.3e-09 36.9 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS70014.1 - 5.9e-07 29.0 0.3 8.8e-06 25.1 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 RUS70014.1 - 2.6e-06 27.5 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS70014.1 - 0.00013 21.6 0.0 0.0016 18.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 RUS70014.1 - 0.0011 18.0 0.1 0.06 12.3 0.0 2.8 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 RUS70014.1 - 0.0021 18.0 0.1 0.95 9.4 0.1 2.2 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 RUS70014.1 - 0.024 14.8 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RUS70014.1 - 0.053 13.8 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 RUS70014.1 - 0.061 13.0 0.1 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 RUS70014.1 - 0.072 12.7 0.1 2.4 7.7 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 RUS70014.1 - 0.094 13.0 0.3 0.67 10.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RUS70014.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PRIMA1 PF16101.5 RUS70015.1 - 0.84 9.7 9.6 0.89 9.6 8.6 1.7 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1056 PF06341.11 RUS70017.1 - 1 9.7 25.4 43 4.5 1.2 6.8 1 1 7 8 8 8 0 Protein of unknown function (DUF1056) GPI PF06560.11 RUS70017.1 - 1.3 8.2 17.3 25 4.0 0.1 6.2 1 1 11 12 12 12 0 Glucose-6-phosphate isomerase (GPI) Phytochelatin PF05023.14 RUS70018.1 - 3.2e-88 294.5 0.0 4.9e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 RUS70018.1 - 0.001 19.6 0.0 0.0044 17.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family Phytochelatin_C PF09328.10 RUS70018.1 - 0.03 13.7 3.1 0.07 12.4 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DOCK_N PF16172.5 RUS70019.1 - 0.073 12.0 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 DOCK N-terminus 7TM_GPCR_Srx PF10328.9 RUS70021.1 - 2.5e-05 24.0 6.8 5.3e-05 23.0 6.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS70021.1 - 0.00031 20.1 2.7 0.0072 15.7 3.4 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS70021.1 - 0.0025 17.8 2.6 0.0048 16.9 2.6 1.4 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa Srg PF02118.21 RUS70021.1 - 0.021 14.5 7.8 0.038 13.7 7.8 1.3 1 0 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srw PF10324.9 RUS70021.1 - 0.11 11.8 7.1 0.27 10.5 2.1 2.4 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4665 PF15679.5 RUS70022.1 - 0.11 13.2 2.1 0.31 11.7 2.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) RRN3 PF05327.11 RUS70022.1 - 0.39 9.2 6.0 0.53 8.8 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ndc1_Nup PF09531.10 RUS70022.1 - 5.8 5.5 7.0 7.5 5.1 7.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0183 PF03676.14 RUS70023.1 - 1.3e-108 363.8 0.2 1.5e-108 363.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Katanin_con80 PF13925.6 RUS70024.1 - 3.4e-48 163.7 0.9 4.7e-48 163.2 0.9 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 RUS70024.1 - 2.8e-43 145.1 20.8 8.6e-13 48.6 0.7 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS70024.1 - 2.5e-17 62.9 0.3 7.6e-05 22.9 0.0 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS70024.1 - 1.8e-07 31.3 0.0 0.0072 16.2 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RUS70024.1 - 6.2e-05 21.8 0.2 2.7 6.5 0.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS70024.1 - 0.005 15.8 0.1 0.058 12.3 0.1 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RUS70024.1 - 0.0062 15.9 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain DUF4505 PF14956.6 RUS70025.1 - 6.1e-87 289.9 0.1 7.6e-87 289.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) PHD PF00628.29 RUS70026.1 - 0.0013 18.5 16.2 0.005 16.7 15.7 2.0 1 1 1 2 2 2 1 PHD-finger Ribosomal_L37e PF01907.19 RUS70026.1 - 0.0048 17.0 0.4 0.0048 17.0 0.4 2.1 1 1 0 2 2 2 1 Ribosomal protein L37e MULE PF10551.9 RUS70027.1 - 4.2e-16 59.1 0.1 4.2e-16 59.1 0.1 2.2 3 0 0 3 3 3 1 MULE transposase domain DUF5575 PF17738.1 RUS70027.1 - 1.3e-12 47.4 0.2 1.8e-12 47.0 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RUS70027.1 - 0.00017 21.4 1.1 0.00021 21.1 0.1 1.7 2 0 0 2 2 2 1 Transposase SWIM PF04434.17 RUS70027.1 - 0.0017 18.0 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.6 RUS70027.1 - 0.005 17.1 0.1 0.017 15.3 0.1 2.0 1 1 0 1 1 1 1 DDE domain Transposase_mut PF00872.18 RUS70027.1 - 0.03 13.2 0.3 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Transposase, Mutator family Pro_racemase PF05544.11 RUS70027.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Proline racemase Adaptin_N PF01602.20 RUS70028.1 - 6.8e-60 203.1 0.2 7.7e-60 202.9 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RUS70028.1 - 2.5e-07 30.9 0.3 5.8e-07 29.7 0.1 1.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 OKR_DC_1 PF01276.20 RUS70030.1 - 0.0035 16.2 0.1 0.0044 15.8 0.1 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain AbiJ_NTD3 PF18860.1 RUS70030.1 - 0.12 11.9 0.4 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 Suf PF05843.14 RUS70030.1 - 0.45 10.5 3.2 14 5.6 0.2 2.7 1 1 2 3 3 3 0 Suppressor of forked protein (Suf) PMM PF03332.13 RUS70030.1 - 0.59 9.9 3.2 7 6.4 0.1 2.3 1 1 1 2 2 2 0 Eukaryotic phosphomannomutase Plasmodium_HRP PF05403.11 RUS70031.1 - 0.0026 17.6 3.1 0.0059 16.4 3.1 1.5 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) DUF1871 PF08958.10 RUS70031.1 - 0.12 12.7 0.3 1.1e+02 3.2 0.0 3.7 1 1 6 7 7 7 0 Domain of unknown function (DUF1871) CRR7 PF12095.8 RUS70032.1 - 0.2 12.1 2.3 2.2e+02 2.4 0.0 4.7 1 1 4 7 7 7 0 Protein CHLORORESPIRATORY REDUCTION 7 Polbeta PF18765.1 RUS70032.1 - 0.29 11.2 37.3 0.16 12.1 3.4 5.5 1 1 5 6 6 6 0 Polymerase beta, Nucleotidyltransferase Cu_amine_oxidN1 PF07833.11 RUS70033.1 - 2.2e-08 34.5 0.5 8.6 6.9 0.0 8.2 1 1 5 6 6 6 1 Copper amine oxidase N-terminal domain HTH_25 PF13413.6 RUS70033.1 - 0.0017 18.2 4.7 17 5.4 0.0 5.3 6 0 0 6 6 6 2 Helix-turn-helix domain GAF PF01590.26 RUS70033.1 - 0.0022 18.6 0.2 94 3.6 0.0 5.9 1 1 1 3 3 3 0 GAF domain RGP PF03214.13 RUS70033.1 - 0.015 14.5 0.0 13 4.9 0.0 3.4 1 1 2 4 4 4 0 Reversibly glycosylated polypeptide GAF_2 PF13185.6 RUS70033.1 - 0.11 12.8 2.6 76 3.6 0.2 5.1 2 2 0 2 2 2 0 GAF domain IN_DBD_C PF00552.21 RUS70033.1 - 0.84 9.0 2.7 36 3.7 0.2 3.6 2 0 0 2 2 2 0 Integrase DNA binding domain zf-FLZ PF04570.14 RUS70034.1 - 2.2e-05 23.8 8.0 43 3.7 0.0 8.7 1 1 11 12 12 12 0 zinc-finger of the FCS-type, C2-C2 DUF3552 PF12072.8 RUS70034.1 - 0.0051 16.3 0.0 3.6 7.0 0.0 2.6 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) Cys_Knot_tox PF17486.2 RUS70034.1 - 0.02 15.1 0.3 38 4.6 0.1 3.5 2 1 2 4 4 4 0 Cystine knot toxins DNAP_B_exo_N PF08452.10 RUS70034.1 - 0.056 12.9 10.3 1.4e+02 2.0 0.0 6.9 6 0 0 6 6 6 0 DNA polymerase family B exonuclease domain, N-terminal DUF4925 PF16272.5 RUS70034.1 - 2.7 7.4 7.1 62 2.9 0.1 3.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4925) Ig_J_chain PF15097.6 RUS70034.1 - 4.9 7.0 11.0 53 3.7 0.4 4.3 1 1 2 4 4 4 0 Immunoglobulin J chain zf-UBP_var PF17807.1 RUS70035.1 - 6.7e-06 25.8 0.9 33 4.3 0.0 6.6 1 1 7 9 9 9 0 Variant UBP zinc finger DUF5010_C PF18099.1 RUS70035.1 - 0.009 16.1 0.1 90 3.3 0.0 4.7 1 1 2 4 4 4 0 DUF5010 C-terminal domain DUF4959 PF16323.5 RUS70035.1 - 0.011 16.1 2.9 28 5.1 0.0 4.5 1 1 2 5 5 5 0 Domain of unknown function (DUF4959) Zona_pellucida PF00100.23 RUS70035.1 - 0.055 13.3 2.5 29 4.4 2.5 3.8 1 1 0 1 1 1 0 Zona pellucida-like domain Herpes_UL82_83 PF05784.11 RUS70035.1 - 0.087 11.7 0.0 9 5.0 0.0 2.8 1 1 0 2 2 2 0 Betaherpesvirus UL82/83 protein N terminus Pox_F12L PF03337.13 RUS70035.1 - 0.091 10.9 4.2 25 2.8 0.1 4.7 1 1 5 6 6 6 0 Poxvirus F12L protein Pentaxin PF00354.17 RUS70035.1 - 0.11 12.2 1.8 28 4.3 0.1 3.3 1 1 4 5 5 5 0 Pentaxin family Ras PF00071.22 RUS70037.1 - 1.8e-60 203.2 0.4 2.3e-60 202.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70037.1 - 1.3e-36 125.5 0.5 1.9e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS70037.1 - 2.3e-15 56.5 0.3 2.9e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS70037.1 - 1.4e-06 28.4 0.1 2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS70037.1 - 0.00018 20.9 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS70037.1 - 0.0017 17.8 0.1 0.0039 16.6 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RUS70037.1 - 0.003 18.0 0.1 0.0048 17.3 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RUS70037.1 - 0.0032 17.4 0.1 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 RUS70037.1 - 0.0052 17.1 0.1 0.0087 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RUS70037.1 - 0.014 15.0 0.2 0.06 12.9 0.2 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 RUS70037.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 RUS70037.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RUS70037.1 - 0.027 14.2 0.1 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 RUS70037.1 - 0.03 13.2 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 RUS70037.1 - 0.033 14.7 0.2 0.057 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 RUS70037.1 - 0.036 14.0 0.3 0.06 13.3 0.3 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 RUS70037.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RUS70037.1 - 0.062 12.8 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 RUS70037.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 RUS70037.1 - 0.088 12.8 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 RUS70037.1 - 0.11 12.2 0.2 0.39 10.4 0.2 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 RUS70037.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 RUS70037.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DnaJ_C PF01556.18 RUS70038.1 - 1.2e-69 233.1 3.6 1.3e-35 122.7 0.9 2.1 1 1 1 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 RUS70038.1 - 1.1e-28 99.3 40.0 7.8e-15 55.0 20.0 2.4 2 0 0 2 2 2 2 DnaJ central domain DnaJ PF00226.31 RUS70038.1 - 6.5e-26 90.2 2.2 1.3e-25 89.2 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.19 RUS70038.1 - 0.00035 20.6 15.3 0.81 9.7 0.6 4.1 4 0 0 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SH3_1 PF00018.28 RUS70038.1 - 0.0053 16.3 1.1 3.8 7.2 0.1 2.5 2 0 0 2 2 2 2 SH3 domain CxC3 PF18804.1 RUS70038.1 - 0.0097 15.7 4.3 1.9 8.4 0.3 2.5 2 0 0 2 2 2 2 CxC3 like cysteine cluster associated with KDZ transposases SH3_9 PF14604.6 RUS70038.1 - 0.1 12.5 0.5 21 5.1 0.1 2.4 2 0 0 2 2 2 0 Variant SH3 domain DUF4537 PF15057.6 RUS70038.1 - 0.13 12.3 0.1 34 4.5 0.0 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4537) DUF2534 PF10749.9 RUS70039.1 - 0.0063 16.7 0.6 1.6 8.9 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2534) LRRC37AB_C PF14914.6 RUS70039.1 - 0.0083 16.1 4.6 0.88 9.5 1.2 2.1 2 0 0 2 2 2 2 LRRC37A/B like protein 1 C-terminal domain PROL5-SMR PF15621.6 RUS70039.1 - 0.0089 16.5 2.3 2.4 8.7 2.3 2.2 1 1 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family DUF1218 PF06749.12 RUS70039.1 - 0.054 14.0 0.9 0.63 10.6 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Ac76 PF05814.11 RUS70039.1 - 0.24 11.4 6.8 4.2 7.5 0.7 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) DUF3149 PF11346.8 RUS70039.1 - 0.37 10.4 6.3 6.5 6.5 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) ODV-E18 PF10717.9 RUS70039.1 - 0.56 10.1 4.1 10 6.1 0.3 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Papilloma_E5 PF03025.14 RUS70039.1 - 2.6 8.2 16.7 0.71 10.1 2.2 2.7 3 0 0 3 3 3 0 Papillomavirus E5 Herpes_UL14 PF03580.14 RUS70040.1 - 0.78 10.0 5.4 0.73 10.1 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein LEDGF PF11467.8 RUS70041.1 - 1.3e-21 76.4 1.5 1.3e-21 76.4 1.5 2.8 3 1 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 RUS70041.1 - 3.3e-11 43.4 0.1 3.3e-11 43.4 0.1 5.1 4 2 1 5 5 5 1 PWWP domain bZIP_2 PF07716.15 RUS70042.1 - 1.7e-13 50.4 15.6 3e-13 49.6 15.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.11 RUS70042.1 - 0.027 13.9 2.7 0.03 13.7 2.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3410 PF11890.8 RUS70042.1 - 0.035 13.9 4.0 0.056 13.2 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) TSC22 PF01166.18 RUS70042.1 - 0.046 14.0 1.5 0.085 13.2 1.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4988 PF16378.5 RUS70042.1 - 0.095 12.4 0.5 0.17 11.5 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function Tho2 PF11262.8 RUS70042.1 - 0.095 11.9 3.8 0.12 11.5 3.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Herpes_UL6 PF01763.16 RUS70042.1 - 0.15 10.6 3.9 0.16 10.5 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.22 RUS70042.1 - 0.21 11.8 8.9 0.14 12.4 6.1 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2514 PF10721.9 RUS70042.1 - 0.32 11.0 7.5 0.42 10.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) bZIP_1 PF00170.21 RUS70042.1 - 0.58 10.3 17.3 0.04 14.0 12.6 1.6 2 0 0 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 RUS70042.1 - 0.7 10.1 10.3 0.71 10.1 9.9 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Zein-binding PF04576.15 RUS70042.1 - 1 9.7 9.1 3.5 8.0 8.5 2.1 1 1 0 1 1 1 0 Zein-binding DUF4094 PF13334.6 RUS70042.1 - 1.1 9.8 4.3 1.9 9.0 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Apis_Csd PF11671.8 RUS70042.1 - 1.2 9.2 6.9 1.6 8.7 6.9 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein DivIC PF04977.15 RUS70042.1 - 5.2 6.9 7.3 0.9 9.4 2.3 2.1 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 RUS70043.1 - 7.6e-15 54.7 9.6 1.3e-14 54.0 9.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS70043.1 - 6.8e-06 26.1 7.6 1.4e-05 25.1 7.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Phlebovirus_NSM PF07246.11 RUS70043.1 - 0.093 12.1 2.8 0.16 11.3 2.8 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CLZ PF16526.5 RUS70043.1 - 2.4 8.6 7.2 0.23 11.8 2.1 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 RUS70043.1 - 3.5 8.2 8.1 0.22 12.0 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.15 RUS70043.1 - 4.3 7.2 8.5 20 5.0 0.2 2.5 1 1 1 2 2 2 0 Septum formation initiator BORG_CEP PF14957.6 RUS70043.1 - 8.9 7.5 10.0 0.66 11.1 0.8 2.5 1 1 1 2 2 2 0 Cdc42 effector TLD PF07534.16 RUS70044.1 - 2.1e-37 128.5 0.9 4.4e-37 127.4 0.3 1.9 2 0 0 2 2 2 1 TLD Syja_N PF02383.18 RUS70045.1 - 1.6e-86 290.5 1.8 2.2e-86 290.1 1.8 1.2 1 0 0 1 1 1 1 SacI homology domain BORCS8 PF10167.9 RUS70046.1 - 0.0078 16.1 0.8 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 INCENP_ARK-bind PF03941.15 RUS70047.1 - 0.026 14.5 0.2 0.097 12.6 0.1 2.1 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region SBF2 PF12335.8 RUS70047.1 - 0.052 13.2 0.4 0.084 12.5 0.3 1.4 1 1 0 1 1 1 0 Myotubularin protein wnt PF00110.19 RUS70048.1 - 3.1e-59 201.1 14.5 1.3e-45 156.4 4.7 2.0 1 1 1 2 2 2 2 wnt family AnfG_VnfG PF03139.15 RUS70048.1 - 0.028 14.5 0.3 0.042 14.0 0.3 1.3 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Cation_ATPase_C PF00689.21 RUS70049.1 - 7.3e-05 22.5 9.3 7.3e-05 22.5 9.3 2.0 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus Coatomer_WDAD PF04053.14 RUS70050.1 - 1.6e-173 577.9 0.1 3.7e-173 576.7 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RUS70050.1 - 2.2e-38 129.6 5.8 6.3e-08 33.2 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS70050.1 - 1.6e-08 34.7 1.0 1.7 9.0 0.0 6.9 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS70050.1 - 0.0039 16.6 0.1 1.3 8.3 0.0 3.8 2 1 1 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 RUS70050.1 - 0.025 13.3 0.5 9.1 4.9 0.0 3.6 2 1 2 4 4 4 0 Nup133 N terminal like Cyclin_N PF00134.23 RUS70051.1 - 5e-45 152.3 0.0 8.6e-45 151.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS70051.1 - 3.1e-24 85.4 0.0 5.2e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 RUS70051.1 - 0.015 16.1 0.1 0.025 15.3 0.1 1.3 1 0 0 1 1 1 0 N-terminal region of cyclin_N RNase_PH PF01138.21 RUS70052.1 - 1.2e-26 93.8 0.0 2.8e-26 92.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS70052.1 - 1e-09 38.3 0.7 3.5e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 MFS_1 PF07690.16 RUS70053.1 - 6.4e-37 127.3 28.5 3.6e-36 124.8 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily cNMP_binding PF00027.29 RUS70055.1 - 2e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1054 PF06335.12 RUS70055.1 - 0.0022 18.0 1.1 0.26 11.2 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1054) Alpha_adaptin_C PF02296.16 RUS70056.1 - 0.0012 19.0 17.7 6.7 6.9 0.4 5.0 1 1 7 8 8 8 8 Alpha adaptin AP2, C-terminal domain CENP-I PF07778.11 RUS70056.1 - 3.4 6.3 14.9 12 4.5 0.4 3.7 1 1 4 5 5 5 0 Mis6 Tafi-CsgC PF10610.9 RUS70056.1 - 4.1 7.7 36.2 15 5.9 0.2 7.9 1 1 10 11 11 11 0 Thin aggregative fimbriae synthesis protein CDK5_activator PF03261.15 RUS70056.1 - 5.1 6.5 14.8 0.88 9.0 5.4 2.1 1 1 1 2 2 2 0 Cyclin-dependent kinase 5 activator protein Corona_3 PF04694.12 RUS70057.1 - 0.0026 18.1 1.6 17 5.8 0.0 3.9 1 1 3 4 4 4 3 Coronavirus ORF3 protein SporV_AA PF12164.8 RUS70057.1 - 0.0055 17.0 8.4 9.7 6.6 0.4 4.3 1 1 3 4 4 4 4 Stage V sporulation protein AA GTP_EFTU PF00009.27 RUS70058.1 - 8.1e-51 172.3 0.0 1.1e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 RUS70058.1 - 4.9e-45 152.1 4.8 9.8e-45 151.1 4.8 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 RUS70058.1 - 4.9e-19 68.2 0.0 1.3e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 RUS70058.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 RUS70058.1 - 3.3e-06 26.9 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 RUS70058.1 - 4.5e-06 27.0 0.1 8.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RUS70058.1 - 0.00023 21.2 0.0 0.00079 19.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.22 RUS70058.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS70058.1 - 0.0074 15.7 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 RUS70058.1 - 0.017 14.5 0.1 0.051 12.9 0.0 1.8 2 0 0 2 2 2 0 Septin Roc PF08477.13 RUS70058.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_C2 PF00648.21 RUS70059.1 - 1.4e-35 122.8 0.1 2.8e-35 121.8 0.1 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS70059.1 - 6e-31 107.6 0.0 1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 RUS70059.1 - 4.6e-12 46.1 0.1 1e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain 7TMR-DISMED2 PF07696.11 RUS70059.1 - 0.021 14.9 0.0 0.43 10.6 0.0 2.3 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 TFA2_Winged_2 PF18121.1 RUS70060.1 - 0.83 9.4 4.7 12 5.7 0.7 4.9 4 1 0 4 4 4 0 TFA2 Winged helix domain 2 7tm_1 PF00001.21 RUS70062.1 - 9.5e-07 28.4 5.3 1.5e-06 27.7 5.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS70062.1 - 1.2e-05 24.7 16.6 0.0057 16.0 11.1 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS70062.1 - 0.038 13.4 12.4 0.19 11.1 12.4 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Annexin_like PF18411.1 RUS70062.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Annexin-like domain PLATZ PF04640.14 RUS70063.1 - 0.16 12.6 1.8 0.77 10.4 0.1 2.6 3 0 0 3 3 3 0 PLATZ transcription factor zf-RING_2 PF13639.6 RUS70065.1 - 3.2e-15 56.2 21.2 5.4e-09 36.2 5.4 3.3 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 RUS70065.1 - 1.7e-12 47.4 12.7 5.8e-06 26.5 2.4 3.6 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS70065.1 - 9.1e-12 44.7 18.1 1.1e-05 25.2 0.6 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS70065.1 - 3.6e-11 42.7 15.9 1.5e-05 24.7 3.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS70065.1 - 6e-10 38.7 18.1 1.9e-06 27.5 1.6 4.1 3 1 1 4 4 4 2 RING-like zinc finger Prok-RING_4 PF14447.6 RUS70065.1 - 1.2e-09 37.8 14.7 3.3e-05 23.7 4.5 3.4 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RUS70065.1 - 2.1e-09 37.1 16.2 0.00015 21.6 4.4 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS70065.1 - 9.8e-08 32.0 11.9 0.00044 20.2 1.7 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RUS70065.1 - 1.3e-07 31.5 21.3 2e-05 24.5 5.0 4.1 3 1 1 4 4 4 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS70065.1 - 5.5e-07 29.3 21.5 0.0014 18.5 5.6 3.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.27 RUS70065.1 - 6e-06 25.6 1.8 1.4e-05 24.4 1.8 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-RING_4 PF14570.6 RUS70065.1 - 0.00066 19.4 12.1 0.16 11.7 0.2 3.1 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RUS70065.1 - 0.0019 17.8 16.1 0.12 12.0 3.5 3.6 3 1 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 RUS70065.1 - 0.0021 18.1 11.1 0.065 13.4 1.7 3.2 3 0 0 3 3 3 2 Zinc-binding RING-finger PHD PF00628.29 RUS70065.1 - 0.0029 17.5 17.3 0.59 10.1 1.2 3.5 3 0 0 3 3 3 2 PHD-finger zf-RING-like PF08746.11 RUS70065.1 - 0.037 14.4 17.0 0.52 10.7 4.6 3.6 3 0 0 3 3 3 0 RING-like domain Zf_RING PF16744.5 RUS70065.1 - 0.066 13.3 15.4 1.8 8.8 1.1 4.0 3 2 0 3 3 3 0 KIAA1045 RING finger zf-Nse PF11789.8 RUS70065.1 - 0.38 10.6 9.3 2.2 8.2 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 RUS70065.1 - 0.59 10.1 19.6 0.21 11.5 2.1 4.4 3 2 1 4 4 4 0 Prokaryotic RING finger family 1 Zn-C2H2_12 PF18112.1 RUS70065.1 - 2.1 8.9 12.6 5.1 7.7 0.2 4.0 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain LIM PF00412.22 RUS70065.1 - 3.6 7.9 8.2 8.1 6.8 0.5 2.9 2 1 0 2 2 2 0 LIM domain STAT_bind PF02864.15 RUS70066.1 - 4.3e-50 169.7 0.2 4.3e-50 169.7 0.2 1.8 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.20 RUS70066.1 - 1.7e-37 128.9 23.2 3.1e-37 128.1 23.2 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain SH2 PF00017.24 RUS70066.1 - 2e-12 47.0 2.4 6.6e-10 38.9 0.0 3.9 4 1 0 4 4 4 2 SH2 domain Ribosomal_L29 PF00831.23 RUS70066.1 - 6.8 6.7 10.0 9.5 6.3 2.8 3.6 4 0 0 4 4 4 0 Ribosomal L29 protein FMO-like PF00743.19 RUS70067.1 - 8.8e-106 354.4 0.0 1.1e-105 354.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS70067.1 - 2.1e-12 46.9 0.1 2.1e-05 24.0 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS70067.1 - 8.6e-06 25.1 0.1 0.00049 19.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 RUS70067.1 - 3.4e-05 23.2 0.0 0.00015 21.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS70067.1 - 0.00088 19.5 0.0 0.0032 17.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Radical_SAM PF04055.21 RUS70068.1 - 8.3e-14 52.3 0.0 1.2e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 RUS70068.1 - 2e-06 28.2 1.9 4e-06 27.2 1.9 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Transcrip_reg PF01709.20 RUS70069.1 - 2.7e-97 324.9 1.4 3e-97 324.8 1.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator ACT_4 PF13291.6 RUS70069.1 - 0.036 14.7 0.1 0.28 11.8 0.1 2.4 2 0 0 2 2 2 0 ACT domain GATase PF00117.28 RUS70070.1 - 5.6e-40 137.2 0.9 8.7e-40 136.5 0.9 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 RUS70070.1 - 5.2e-11 42.4 0.1 4.7e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.17 RUS70070.1 - 6.9e-11 41.7 0.2 4.5e-08 32.5 0.1 2.5 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 RUS70070.1 - 1.7e-10 41.0 3.5 5.6e-09 36.1 3.2 3.0 1 1 1 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.16 RUS70070.1 - 4.3e-05 22.5 0.0 0.00015 20.7 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 RUS70070.1 - 0.0015 18.0 0.0 0.065 12.7 0.0 2.3 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 RUS70070.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.19 RUS70070.1 - 0.0044 16.4 0.3 0.027 13.8 0.1 2.0 2 0 0 2 2 2 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 RUS70070.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 PP-loop family Pyr_redox_2 PF07992.14 RUS70071.1 - 5e-33 114.6 1.9 5.5e-33 114.4 1.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS70071.1 - 3.8e-18 65.8 0.9 5.7e-18 65.2 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS70071.1 - 5.1e-13 48.9 1.6 5.6e-13 48.8 1.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 RUS70071.1 - 1.8e-05 24.7 0.2 2.5e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RUS70071.1 - 0.00037 20.5 0.2 0.00052 20.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 RUS70071.1 - 0.0035 17.4 0.3 0.0099 15.9 0.3 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 RUS70071.1 - 0.0093 15.6 2.6 0.43 10.1 0.6 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 RUS70071.1 - 0.01 16.3 0.1 0.013 15.9 0.1 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RUS70071.1 - 0.018 14.3 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 RUS70071.1 - 0.019 14.2 0.7 0.02 14.2 0.7 1.2 1 1 0 1 1 1 0 FAD binding domain ApbA PF02558.16 RUS70071.1 - 0.027 14.1 0.2 0.053 13.2 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 RUS70071.1 - 0.028 14.4 1.2 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 RUS70071.1 - 0.031 13.4 0.5 5.6 6.0 0.1 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 RUS70071.1 - 0.062 12.7 0.4 0.17 11.3 0.3 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BetaGal_dom3 PF13363.6 RUS70071.1 - 0.07 12.7 1.9 0.66 9.6 0.4 2.3 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 HI0933_like PF03486.14 RUS70071.1 - 0.095 11.4 3.1 0.15 10.7 0.1 1.9 1 1 1 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 RUS70071.1 - 0.4 10.2 6.4 1.6 8.3 6.4 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MMR_HSR1 PF01926.23 RUS70072.1 - 7.1e-16 58.3 0.1 1.4e-14 54.2 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS70072.1 - 7.3e-08 32.1 0.3 4.2e-07 29.6 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS70072.1 - 3.1e-06 27.2 0.2 9.5e-06 25.6 0.2 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 RUS70072.1 - 0.0005 20.2 0.1 0.011 15.9 0.1 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 RUS70072.1 - 0.013 15.1 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 RUS70072.1 - 0.015 14.7 0.1 0.032 13.7 0.1 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 RUS70072.1 - 0.072 13.6 0.0 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RUS70072.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 RUS70072.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family PseudoU_synth_1 PF01416.20 RUS70073.1 - 4e-20 72.3 0.0 6.2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase YchF-GTPase_C PF06071.13 RUS70074.1 - 1.6e-39 134.0 0.0 3.1e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RUS70074.1 - 1.5e-05 25.1 0.1 3.6e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 RUS70074.1 - 0.029 14.4 0.2 0.13 12.3 0.2 2.1 1 1 0 1 1 1 0 TGS domain Pox_D5 PF03288.16 RUS70074.1 - 0.11 13.0 0.1 0.35 11.4 0.1 1.8 1 1 0 1 1 1 0 Poxvirus D5 protein-like Pyr_redox_2 PF07992.14 RUS70075.1 - 8.8e-27 94.1 0.1 9.7e-27 93.9 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS70075.1 - 2.4e-14 53.7 0.4 4.8e-14 52.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS70075.1 - 0.00037 19.8 0.6 0.00054 19.3 0.6 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF5396 PF17374.2 RUS70075.1 - 0.013 13.4 0.2 0.014 13.3 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) Guanylate_kin PF00625.21 RUS70076.1 - 6.2e-48 162.9 0.6 6.8e-48 162.8 0.6 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF4921 PF16268.5 RUS70076.1 - 0.012 14.4 0.8 0.012 14.4 0.1 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) ABC_tran PF00005.27 RUS70076.1 - 0.025 15.1 0.1 0.036 14.6 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 RUS70076.1 - 0.028 14.8 0.3 0.045 14.1 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 RUS70076.1 - 0.043 13.9 0.1 0.065 13.3 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS70076.1 - 0.058 13.7 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 RUS70076.1 - 0.063 13.5 0.3 0.14 12.4 0.2 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 RUS70076.1 - 0.071 12.8 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 RUS70076.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase QRPTase_C PF01729.19 RUS70077.1 - 6.1e-53 179.1 0.3 8.6e-53 178.6 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RUS70077.1 - 9.4e-21 73.7 0.0 1.9e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain A_deaminase PF00962.22 RUS70078.1 - 2.4e-54 184.9 0.0 2.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase HTH_ABP1_N PF18107.1 RUS70078.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Glyco_transf_7N PF13733.6 RUS70079.1 - 2.7e-42 143.6 0.0 4e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS70079.1 - 2.7e-21 75.0 0.3 5e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Colicin_Ia PF11504.8 RUS70080.1 - 0.016 15.3 0.2 57 3.9 0.0 4.3 2 1 3 5 5 5 0 Colicin Ia Baculo_PEP_C PF04513.12 RUS70081.1 - 4.5e-07 30.0 0.9 5.3e-07 29.8 0.9 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Erp_C PF06780.11 RUS70081.1 - 1.4e-05 25.1 9.3 0.0056 16.7 3.7 2.6 1 1 1 2 2 2 2 Erp protein C-terminus SesA PF17107.5 RUS70081.1 - 1.9e-05 24.9 1.2 0.00058 20.0 1.2 2.4 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CREPT PF16566.5 RUS70081.1 - 5.1e-05 23.5 5.0 6.7e-05 23.1 5.0 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 RUS70081.1 - 6.4e-05 23.0 1.6 7.9e-05 22.7 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF745 PF05335.13 RUS70081.1 - 9e-05 22.3 0.4 9.8e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 RUS70081.1 - 0.00016 21.4 3.0 0.00017 21.3 3.0 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit NAAA-beta PF15508.6 RUS70081.1 - 0.00018 21.7 2.6 0.042 14.2 0.8 2.8 1 1 2 3 3 3 2 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Spc7 PF08317.11 RUS70081.1 - 0.00024 20.1 3.3 0.00026 20.0 3.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SKA1 PF07160.12 RUS70081.1 - 0.00035 20.5 5.5 0.00045 20.2 5.5 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DASH_Duo1 PF08651.10 RUS70081.1 - 0.00041 20.1 6.5 0.034 13.9 4.4 2.3 1 1 1 2 2 2 2 DASH complex subunit Duo1 TBCC_N PF16752.5 RUS70081.1 - 0.00043 20.7 0.8 0.00054 20.4 0.8 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain CHASE3 PF05227.13 RUS70081.1 - 0.00052 19.9 0.5 0.00061 19.7 0.5 1.3 1 0 0 1 1 1 1 CHASE3 domain CorA PF01544.18 RUS70081.1 - 0.00055 19.3 5.4 0.00071 19.0 5.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 RUS70081.1 - 0.00059 19.9 3.4 0.00069 19.6 3.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 RUS70081.1 - 0.00064 20.1 3.5 0.092 13.2 3.5 2.6 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Strumpellin PF10266.9 RUS70081.1 - 0.0007 17.4 7.5 0.00081 17.2 7.5 1.1 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin P4Ha_N PF08336.11 RUS70081.1 - 0.00079 19.4 13.5 0.1 12.6 13.5 2.2 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SMBP PF16785.5 RUS70081.1 - 0.00082 19.6 4.4 0.0019 18.4 4.4 1.7 1 1 0 1 1 1 1 Small metal-binding protein KxDL PF10241.9 RUS70081.1 - 0.00087 19.5 4.3 0.028 14.7 1.8 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein TMPIT PF07851.13 RUS70081.1 - 0.0013 18.1 4.2 0.0014 18.0 4.2 1.1 1 0 0 1 1 1 1 TMPIT-like protein Laminin_II PF06009.12 RUS70081.1 - 0.0015 18.5 0.7 0.0022 18.0 0.7 1.3 1 0 0 1 1 1 1 Laminin Domain II Rx_N PF18052.1 RUS70081.1 - 0.0021 18.3 1.3 0.042 14.1 1.2 2.4 1 1 0 1 1 1 1 Rx N-terminal domain DUF1241 PF06840.11 RUS70081.1 - 0.0022 17.7 1.8 0.029 14.0 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1241) DUF16 PF01519.16 RUS70081.1 - 0.0031 18.0 3.9 0.0039 17.7 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF948 PF06103.11 RUS70081.1 - 0.0033 17.6 0.0 0.0083 16.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 RUS70081.1 - 0.0056 15.8 10.7 0.013 14.7 10.7 1.6 1 1 0 1 1 1 1 Autophagy protein Apg17 HIP1_clath_bdg PF16515.5 RUS70081.1 - 0.0058 17.2 2.6 0.019 15.5 2.6 1.8 1 1 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 RUS70081.1 - 0.0061 16.8 9.6 0.009 16.2 9.6 1.4 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Syntaxin PF00804.25 RUS70081.1 - 0.0066 16.1 1.0 0.0075 16.0 1.0 1.1 1 0 0 1 1 1 1 Syntaxin Prominin PF05478.11 RUS70081.1 - 0.0067 14.5 4.7 0.0073 14.3 4.7 1.1 1 0 0 1 1 1 1 Prominin IFT57 PF10498.9 RUS70081.1 - 0.0076 15.3 9.7 0.0089 15.0 9.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 RUS70081.1 - 0.0082 16.5 1.8 0.59 10.6 0.2 2.5 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) THOC7 PF05615.13 RUS70081.1 - 0.0093 16.3 5.3 0.014 15.7 5.3 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 TCTP PF00838.17 RUS70081.1 - 0.0096 16.3 15.2 1.2 9.5 9.8 3.3 1 1 1 2 2 2 1 Translationally controlled tumour protein CdvA PF18822.1 RUS70081.1 - 0.0097 15.7 6.4 0.78 9.6 1.0 2.6 1 1 1 2 2 2 2 CdvA-like coiled-coil domain DUF2207 PF09972.9 RUS70081.1 - 0.01 14.7 0.3 0.011 14.5 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3450 PF11932.8 RUS70081.1 - 0.011 15.1 4.9 0.014 14.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glutaredoxin2_C PF04399.13 RUS70081.1 - 0.011 15.6 5.3 0.3 10.9 0.9 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DHC_N1 PF08385.12 RUS70081.1 - 0.013 14.1 6.5 0.015 13.9 6.5 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 ISG65-75 PF11727.8 RUS70081.1 - 0.013 14.7 6.0 0.031 13.5 6.0 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein ApoLp-III PF07464.11 RUS70081.1 - 0.014 15.5 0.5 0.019 15.1 0.5 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.12 RUS70081.1 - 0.015 15.5 1.1 1 9.6 0.2 2.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DASH_Dad2 PF08654.10 RUS70081.1 - 0.015 15.7 0.7 0.14 12.6 0.7 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 Tweety PF04906.13 RUS70081.1 - 0.016 13.9 3.4 0.02 13.6 3.4 1.3 1 0 0 1 1 1 0 Tweety DIL PF01843.19 RUS70081.1 - 0.017 15.4 4.3 0.16 12.3 0.9 2.0 1 1 1 2 2 2 0 DIL domain AI-2E_transport PF01594.16 RUS70081.1 - 0.018 14.2 6.1 0.027 13.6 6.1 1.4 1 1 0 1 1 1 0 AI-2E family transporter DUF5063 PF16702.5 RUS70081.1 - 0.019 15.4 7.0 0.72 10.2 7.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) FH2 PF02181.23 RUS70081.1 - 0.019 14.1 1.6 0.02 14.0 1.6 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain Frataxin_Cyay PF01491.16 RUS70081.1 - 0.02 15.0 6.6 15 5.7 6.6 2.7 1 1 0 1 1 1 0 Frataxin-like domain Fmp27_WPPW PF10359.9 RUS70081.1 - 0.021 13.7 5.4 0.022 13.6 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tektin PF03148.14 RUS70081.1 - 0.022 13.5 2.7 0.025 13.3 2.7 1.1 1 0 0 1 1 1 0 Tektin family Phage_int_SAM_5 PF13102.6 RUS70081.1 - 0.025 14.9 9.0 0.053 13.9 9.0 1.7 1 1 0 1 1 1 0 Phage integrase SAM-like domain FAP206 PF12018.8 RUS70081.1 - 0.027 14.0 9.9 0.032 13.8 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function FANCI_S3 PF14677.6 RUS70081.1 - 0.028 14.1 8.7 0.14 11.9 8.7 1.9 1 1 0 1 1 1 0 FANCI solenoid 3 NEMO PF11577.8 RUS70081.1 - 0.03 14.4 5.3 0.045 13.8 5.3 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Nairo_nucleo PF02477.15 RUS70081.1 - 0.031 13.1 1.5 0.098 11.5 1.0 1.8 1 1 1 2 2 2 0 Nucleocapsid N protein WEMBL PF05701.11 RUS70081.1 - 0.034 12.9 0.6 0.033 12.9 0.6 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Sec8_exocyst PF04048.14 RUS70081.1 - 0.035 14.0 11.0 0.046 13.6 11.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Pox_A3L PF05288.11 RUS70081.1 - 0.038 14.0 2.9 2.2 8.3 0.2 2.4 1 1 1 2 2 2 0 Poxvirus A3L Protein IPK PF03770.16 RUS70081.1 - 0.038 13.8 6.5 0.072 12.9 6.3 1.6 1 1 0 1 1 1 0 Inositol polyphosphate kinase Effector_1 PF04518.12 RUS70081.1 - 0.042 13.0 5.3 0.049 12.7 5.3 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Pro_CA PF00484.19 RUS70081.1 - 0.043 14.1 1.1 0.076 13.3 1.1 1.5 1 1 0 1 1 1 0 Carbonic anhydrase DUF4199 PF13858.6 RUS70081.1 - 0.043 14.2 2.9 0.35 11.2 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) UPF0184 PF03670.13 RUS70081.1 - 0.046 14.1 0.7 1.7 9.1 0.6 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) PEPcase_2 PF14010.6 RUS70081.1 - 0.049 12.1 3.0 0.051 12.1 3.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF357 PF04010.13 RUS70081.1 - 0.05 13.7 3.0 2.7 8.1 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF357) FliJ PF02050.16 RUS70081.1 - 0.052 13.8 13.0 0.069 13.4 13.0 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein FapA PF03961.13 RUS70081.1 - 0.055 12.1 7.7 0.057 12.0 7.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4201 PF13870.6 RUS70081.1 - 0.057 13.2 11.2 0.29 10.9 11.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IZUMO PF15005.6 RUS70081.1 - 0.061 13.8 2.7 0.08 13.5 2.7 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated GLE1 PF07817.13 RUS70081.1 - 0.068 12.4 3.8 0.082 12.1 3.8 1.2 1 0 0 1 1 1 0 GLE1-like protein YjcZ PF13990.6 RUS70081.1 - 0.075 12.4 1.0 0.25 10.7 0.9 1.7 1 1 0 1 1 1 0 YjcZ-like protein YqjK PF13997.6 RUS70081.1 - 0.079 13.2 0.1 1.1 9.5 0.0 2.2 1 1 1 2 2 2 0 YqjK-like protein MCPsignal PF00015.21 RUS70081.1 - 0.08 12.7 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Acyl-CoA_dh_C PF12806.7 RUS70081.1 - 0.08 13.1 0.0 0.33 11.1 0.0 1.9 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like FlgN PF05130.12 RUS70081.1 - 0.09 13.3 6.5 2 8.9 6.5 2.2 1 1 0 1 1 1 0 FlgN protein FPP PF05911.11 RUS70081.1 - 0.093 10.9 4.9 0.095 10.9 4.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Phage_int_SAM_4 PF13495.6 RUS70081.1 - 0.1 13.0 11.4 1.1 9.8 9.9 2.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain dCache_1 PF02743.18 RUS70081.1 - 0.12 12.1 4.4 0.2 11.4 4.4 1.5 1 1 0 1 1 1 0 Cache domain phiKZ_IP PF12699.7 RUS70081.1 - 0.12 11.5 0.7 0.33 10.0 0.7 1.9 1 1 0 1 1 1 0 phiKZ-like phage internal head proteins IDO PF01231.18 RUS70081.1 - 0.14 10.9 6.6 0.35 9.6 2.2 1.9 1 1 0 1 1 1 0 Indoleamine 2,3-dioxygenase KAR9 PF08580.10 RUS70081.1 - 0.14 10.6 4.3 0.17 10.4 4.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Lipoprotein_2 PF00921.17 RUS70081.1 - 0.14 11.6 0.4 0.41 10.2 0.4 1.8 1 1 0 1 1 1 0 Borrelia lipoprotein Med28 PF11594.8 RUS70081.1 - 0.15 12.1 6.2 1.3 9.1 1.0 2.7 1 1 1 2 2 2 0 Mediator complex subunit 28 BLOC1_2 PF10046.9 RUS70081.1 - 0.15 12.3 9.3 0.9 9.9 4.8 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PLA2G12 PF06951.11 RUS70081.1 - 0.17 11.7 0.8 1.9 8.4 0.8 2.2 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) 7TMR-HDED PF07697.11 RUS70081.1 - 0.17 11.9 1.8 0.2 11.7 1.8 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Serine_rich PF08824.10 RUS70081.1 - 0.18 11.8 1.4 0.41 10.6 1.4 1.7 1 1 0 1 1 1 0 Serine rich protein interaction domain Complex1_LYR_2 PF13233.6 RUS70081.1 - 0.19 12.5 20.4 2.6e+03 -0.7 20.4 3.0 1 1 0 1 1 0 0 Complex1_LYR-like Adenylsucc_synt PF00709.21 RUS70081.1 - 0.19 10.6 1.0 0.23 10.3 1.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase PLU-1 PF08429.11 RUS70081.1 - 0.2 10.8 6.3 0.46 9.6 6.3 1.6 1 1 0 1 1 1 0 PLU-1-like protein SF3A3 PF16837.5 RUS70081.1 - 0.21 12.1 19.3 3.7e+02 1.7 19.3 4.0 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 MscS_porin PF12795.7 RUS70081.1 - 0.22 11.1 5.2 0.48 9.9 5.2 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain XhlA PF10779.9 RUS70081.1 - 0.22 11.8 3.0 1.1 9.6 0.6 2.0 1 1 1 2 2 2 0 Haemolysin XhlA Plk4_PB2 PF18409.1 RUS70081.1 - 0.22 12.2 5.9 20 5.9 5.9 2.6 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Sec2p PF06428.11 RUS70081.1 - 0.23 11.5 10.3 0.83 9.7 2.6 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Mlp PF03304.13 RUS70081.1 - 0.27 11.5 3.5 1.1 9.4 3.5 2.0 1 1 0 1 1 1 0 Mlp lipoprotein family SseC PF04888.12 RUS70081.1 - 0.28 10.7 5.2 0.99 8.9 1.0 2.4 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family YozE_SAM_like PF06855.12 RUS70081.1 - 0.31 11.3 12.9 1.4 9.2 2.6 3.2 1 1 3 4 4 4 0 YozE SAM-like fold Mt_ATP-synt_D PF05873.12 RUS70081.1 - 0.34 10.8 5.1 2.7 7.8 0.8 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) MnmE_helical PF12631.7 RUS70081.1 - 0.34 11.0 3.3 0.6 10.2 3.3 1.5 1 1 0 1 1 1 0 MnmE helical domain PHA_synth_III_E PF09712.10 RUS70081.1 - 0.35 9.9 2.4 1.5 7.8 2.1 1.5 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Med9 PF07544.13 RUS70081.1 - 0.35 11.0 8.7 1.9 8.6 7.9 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Zwint PF15556.6 RUS70081.1 - 0.37 10.3 6.8 0.45 10.0 6.8 1.1 1 0 0 1 1 1 0 ZW10 interactor LXG PF04740.12 RUS70081.1 - 0.37 10.5 11.8 1.9 8.1 11.8 2.0 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF5344 PF17279.2 RUS70081.1 - 0.39 11.3 11.1 1.2 9.8 4.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) MitMem_reg PF13012.6 RUS70081.1 - 0.39 11.2 11.7 35 4.9 11.7 2.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Goodbye PF17109.5 RUS70081.1 - 0.39 11.2 2.8 2.1 8.8 2.8 2.2 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Atg14 PF10186.9 RUS70081.1 - 0.42 9.7 8.8 0.6 9.1 8.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dna2 PF08696.11 RUS70081.1 - 0.43 10.4 5.2 1.1 9.0 5.2 1.7 1 1 0 1 1 1 0 DNA replication factor Dna2 Dus PF01207.17 RUS70081.1 - 0.44 9.6 2.5 0.57 9.2 2.5 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) BRCA-2_OB3 PF09104.10 RUS70081.1 - 0.49 10.0 5.0 6.1 6.5 0.7 2.2 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 RecG_N PF17190.4 RUS70081.1 - 0.51 11.1 11.0 1 10.1 10.9 1.7 1 1 0 1 1 1 0 RecG N-terminal helical domain HMMR_N PF15905.5 RUS70081.1 - 0.53 9.7 7.1 0.59 9.5 7.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TetR_C_27 PF17935.1 RUS70081.1 - 0.58 10.2 8.2 11 6.1 0.7 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain USP8_interact PF08941.10 RUS70081.1 - 0.69 9.7 4.9 0.61 9.9 1.8 1.7 1 1 1 2 2 2 0 USP8 interacting Glyco_trans_1_2 PF13524.6 RUS70081.1 - 0.78 10.2 5.0 11 6.5 0.7 2.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 DUF4806 PF16064.5 RUS70081.1 - 0.79 10.1 3.7 46 4.4 3.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) MSA-2c PF12238.8 RUS70081.1 - 0.84 9.6 2.9 1 9.3 2.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2990 PF11693.8 RUS70081.1 - 0.92 9.7 4.3 35 4.7 4.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2990) DUF4795 PF16043.5 RUS70081.1 - 0.96 9.0 10.6 2.2 7.8 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ERp29 PF07749.12 RUS70081.1 - 1.1 10.2 7.7 2.3 9.2 7.7 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF489 PF04356.12 RUS70081.1 - 1.4 8.9 8.3 9 6.3 8.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF489) T4SS PF07996.11 RUS70081.1 - 1.5 9.2 10.4 1.2e+02 3.0 10.4 2.1 1 1 0 1 1 1 0 Type IV secretion system proteins Mis14 PF08641.12 RUS70081.1 - 1.7 9.0 6.0 44 4.4 6.0 2.8 1 1 0 1 1 1 0 Kinetochore protein Mis14 like ANAPC4 PF12896.7 RUS70081.1 - 1.8 8.0 12.4 24 4.4 12.4 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Cob_adeno_trans PF01923.18 RUS70081.1 - 1.9 8.6 6.6 1.9 8.6 3.0 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Thioredoxin_11 PF18078.1 RUS70081.1 - 2.5 8.3 11.9 5.5e+02 0.7 11.9 3.5 1 1 0 1 1 1 0 Thioredoxin-like SNTX domain Phage_Mu_Gam PF07352.12 RUS70081.1 - 2.9 7.8 8.8 4.8 7.1 8.8 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein YvfG PF09628.10 RUS70081.1 - 3.8 8.0 13.0 3.4 8.1 1.1 3.2 1 1 2 3 3 3 0 YvfG protein EMP24_GP25L PF01105.24 RUS70081.1 - 3.8 7.4 8.3 10 6.0 8.3 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LOH1CR12 PF10158.9 RUS70081.1 - 3.9 7.5 12.7 4.9 7.2 5.9 2.0 1 1 1 2 2 2 0 Tumour suppressor protein MAP65_ASE1 PF03999.12 RUS70081.1 - 4.4 5.9 13.5 11 4.6 13.4 1.7 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MetOD2 PF18548.1 RUS70081.1 - 5.6 7.1 10.6 8.8 6.5 0.5 2.8 1 1 2 3 3 3 0 Metanogen output domain 2 Sec1 PF00995.23 RUS70081.1 - 6.8 5.8 13.5 17 4.5 13.5 1.7 1 1 0 1 1 1 0 Sec1 family zf-C4H2 PF10146.9 RUS70081.1 - 6.9 6.9 8.8 7.5 6.8 8.8 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Med8 PF10232.9 RUS70081.1 - 7.4 6.1 6.9 7.5 6.1 5.7 1.6 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 AAA_23 PF13476.6 RUS70081.1 - 8.4 6.8 11.1 16 6.0 11.1 1.6 1 1 0 1 1 1 0 AAA domain DUF1043 PF06295.12 RUS70081.1 - 8.5 6.4 20.9 1e+03 -0.3 20.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Hormone_3 PF00159.18 RUS70081.1 - 9.6 6.4 21.4 1.1 9.3 1.2 4.4 1 1 4 5 5 5 0 Pancreatic hormone peptide IF-2B PF01008.17 RUS70082.1 - 2.1e-64 217.4 0.0 5.1e-64 216.2 0.0 1.6 1 1 1 2 2 2 1 Initiation factor 2 subunit family DPPIV_N PF00930.21 RUS70083.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 RUS70083.1 - 0.13 12.2 0.3 8.2 6.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat 4F5 PF04419.14 RUS70084.1 - 1.1e-05 26.2 13.7 1.1e-05 26.2 13.7 1.8 2 0 0 2 2 2 1 4F5 protein family zf-met PF12874.7 RUS70084.1 - 0.0046 17.3 0.1 0.0092 16.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS70084.1 - 0.0094 16.2 0.3 0.016 15.5 0.3 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4230 PF14014.6 RUS70084.1 - 0.016 15.5 0.1 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) PRP21_like_P PF12230.8 RUS70084.1 - 0.017 15.0 0.8 0.021 14.7 0.8 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_jaz PF12171.8 RUS70084.1 - 0.027 14.7 0.2 0.048 14.0 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RUS70084.1 - 0.031 15.1 1.2 0.057 14.3 1.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF629 PF04780.12 RUS70084.1 - 0.058 11.9 0.1 0.069 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Rad50_zn_hook PF04423.14 RUS70084.1 - 0.1 12.5 1.7 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Redoxin PF08534.10 RUS70084.1 - 0.12 12.1 2.0 0.29 10.8 2.1 1.5 1 1 1 2 2 2 0 Redoxin SSF PF00474.17 RUS70085.1 - 3.8e-14 52.4 14.0 1.2e-13 50.7 14.0 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family Lectin_C PF00059.21 RUS70086.1 - 6.4e-08 33.3 1.1 1.9e-07 31.8 0.2 2.2 2 1 0 2 2 2 1 Lectin C-type domain CBM_5_12_2 PF14600.6 RUS70087.1 - 3.2e-05 23.7 0.4 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 Cellulose-binding domain RelA_SpoT PF04607.17 RUS70087.1 - 0.024 14.9 0.1 9.3 6.6 0.0 2.2 1 1 0 2 2 2 0 Region found in RelA / SpoT proteins DUF5087 PF17006.5 RUS70087.1 - 0.049 13.2 3.0 3.9 6.9 0.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5087) Attractin PF08037.11 RUS70087.1 - 0.05 13.6 4.6 3.6 7.7 0.3 2.6 2 0 0 2 2 2 0 Attractin family RhodobacterPufX PF11511.8 RUS70087.1 - 0.087 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PAH PF02671.21 RUS70088.1 - 1.5e-18 66.6 0.0 2.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat DEFB136 PF17333.2 RUS70089.1 - 4.4e-05 23.4 4.6 0.028 14.4 0.8 2.5 2 0 0 2 2 2 2 Beta defensin 136 Ank_2 PF12796.7 RUS70091.1 - 3.7e-11 43.5 0.1 0.00011 22.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS70091.1 - 5.3e-11 42.5 0.1 3.9e-06 27.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS70091.1 - 6.1e-09 36.2 0.4 1.7e-06 28.5 0.0 2.9 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS70091.1 - 1.7e-08 34.5 0.6 0.0058 16.9 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS70091.1 - 1.3e-07 31.3 0.4 0.036 14.6 0.0 3.9 3 2 0 3 3 3 2 Ankyrin repeat DUF3522 PF12036.8 RUS70092.1 - 6.4e-09 36.4 8.3 1.5e+02 2.6 0.0 10.8 1 1 11 12 12 12 0 Protein of unknown function (DUF3522) P22_portal PF16510.5 RUS70092.1 - 1.8e-08 33.5 0.0 1.3e+02 1.0 0.0 10.1 1 1 1 12 12 12 0 Phage P22-like portal protein CEP19 PF14933.6 RUS70093.1 - 1.3e-42 145.9 0.1 1.5e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 CEP19-like protein ENT PF03735.14 RUS70094.1 - 6.7e-29 99.8 2.3 1.4e-28 98.7 2.3 1.6 1 0 0 1 1 1 1 ENT domain Bromodomain PF00439.25 RUS70094.1 - 4.5e-19 68.3 0.1 9.4e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Inhibitor_I53 PF11714.8 RUS70094.1 - 0.16 12.1 3.3 0.68 10.2 3.3 2.1 1 0 0 1 1 1 0 Thrombin inhibitor Madanin SPC25 PF06703.11 RUS70095.1 - 4.5e-44 150.1 0.1 5.4e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) IFT81_CH PF18383.1 RUS70096.1 - 6.7e-55 184.6 1.1 6.7e-55 184.6 1.1 1.9 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain Laminin_II PF06009.12 RUS70096.1 - 0.023 14.7 1.7 0.05 13.6 1.7 1.5 1 0 0 1 1 1 0 Laminin Domain II MLTR_LBD PF17765.1 RUS70096.1 - 0.026 14.6 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain BLOC1_2 PF10046.9 RUS70096.1 - 0.052 13.8 0.9 0.052 13.8 0.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.6 RUS70096.1 - 0.16 12.4 4.5 0.34 11.3 4.5 1.5 1 0 0 1 1 1 0 Syntaxin-like protein YabA PF06156.13 RUS70096.1 - 0.2 12.3 6.1 0.46 11.2 6.1 1.7 1 0 0 1 1 1 0 Initiation control protein YabA RapH_N PF18801.1 RUS70096.1 - 0.2 11.7 2.1 0.56 10.3 2.1 1.8 1 1 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Vfa1 PF08432.10 RUS70096.1 - 0.21 11.9 4.0 0.35 11.2 4.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 kleA_kleC PF17383.2 RUS70096.1 - 0.26 11.6 4.1 1.5 9.2 0.7 2.9 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A LMBR1 PF04791.16 RUS70096.1 - 0.35 9.7 0.8 0.41 9.5 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HALZ PF02183.18 RUS70096.1 - 1.1 9.6 6.5 4.9 7.4 1.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rho_Binding PF08912.11 RUS70096.1 - 6.6 7.6 12.9 2.2 9.1 4.2 3.0 2 1 1 3 3 3 0 Rho Binding Laminin_EGF PF00053.24 RUS70097.1 - 2.6e-05 24.2 47.0 0.14 12.3 4.7 7.3 2 2 3 5 5 5 3 Laminin EGF domain Phtf-FEM1B_bdg PF12129.8 RUS70098.1 - 4.7e-52 175.9 2.3 4.7e-52 175.9 2.3 2.1 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor Pentapeptide_4 PF13599.6 RUS70099.1 - 1.9e-08 34.4 2.5 0.00075 19.6 1.3 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Asp_protease_2 PF13650.6 RUS70099.1 - 0.0047 17.5 0.0 24 5.6 0.0 3.3 1 1 2 3 3 3 2 Aspartyl protease Methyltransf_1N PF02870.15 RUS70099.1 - 0.13 13.1 3.7 8.6 7.3 0.2 3.1 1 1 1 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain CAMSAP_CH PF11971.8 RUS70099.1 - 0.26 11.2 2.5 4.3 7.2 0.6 3.3 2 1 2 4 4 4 0 CAMSAP CH domain DUF5360 PF17314.2 RUS70100.1 - 0.035 14.2 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5360) OATP PF03137.20 RUS70101.1 - 7.7e-128 427.2 17.8 9.6e-128 426.8 17.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS70101.1 - 6.8e-13 48.3 34.5 1e-11 44.4 32.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS70101.1 - 0.0077 16.3 11.0 0.021 14.9 11.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF2721 PF11026.8 RUS70101.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) DUF1011 PF06237.12 RUS70103.1 - 2.1e-25 88.9 6.2 2.1e-25 88.9 6.2 3.4 4 1 1 5 5 5 1 Protein of unknown function (DUF1011) RT_RNaseH PF17917.1 RUS70104.1 - 9.1e-18 64.5 0.0 2.5e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS70104.1 - 1.7e-14 53.7 0.0 3.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ACCA PF03255.14 RUS70104.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Astacin PF01400.24 RUS70107.1 - 0.035 13.7 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Astacin PF01400.24 RUS70108.1 - 2.4e-47 161.0 0.2 3e-47 160.7 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 RUS70108.1 - 0.0018 18.2 1.2 0.0026 17.6 0.2 1.7 2 0 0 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 RUS70108.1 - 0.0035 16.3 0.3 0.0035 16.3 0.3 1.9 2 0 0 2 2 2 1 Peptidase M66 Myc_N PF01056.18 RUS70108.1 - 0.0037 17.2 0.5 0.0043 17.0 0.5 1.1 1 0 0 1 1 1 1 Myc amino-terminal region DUF4953 PF16313.5 RUS70108.1 - 0.016 14.5 0.8 0.025 13.8 0.8 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 RUS70108.1 - 0.035 14.6 0.8 0.074 13.6 0.8 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS70108.1 - 0.09 12.4 1.2 0.17 11.5 0.8 1.7 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like eIF3_subunit PF08597.10 RUS70108.1 - 0.9 9.4 6.3 1.3 8.9 6.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Metallothio_5 PF02067.15 RUS70108.1 - 1.2 9.3 12.4 2 8.6 12.4 1.3 1 0 0 1 1 1 0 Metallothionein family 5 Metallopep PF12044.8 RUS70108.1 - 2.6 6.6 4.0 0.55 8.8 0.7 1.4 2 0 0 2 2 2 0 Putative peptidase family EAR PF07897.11 RUS70110.1 - 2.5 7.8 4.5 16 5.2 0.6 3.5 2 1 2 4 4 4 0 Ethylene-responsive binding factor-associated repression His_Phos_2 PF00328.22 RUS70111.1 - 7.7e-23 81.5 0.8 5.3e-13 49.1 0.0 3.2 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) DUF829 PF05705.14 RUS70112.1 - 2.5e-37 129.1 0.7 3.4e-37 128.6 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ser_hydrolase PF06821.13 RUS70112.1 - 0.01 15.7 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Acetyltransf_1 PF00583.25 RUS70113.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS70113.1 - 8.3e-12 45.2 0.0 2.5e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS70113.1 - 1.7e-11 44.4 0.0 3.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS70113.1 - 0.00015 21.7 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 RUS70113.1 - 0.00057 19.4 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 RUS70113.1 - 0.00071 19.7 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RUS70113.1 - 0.02 15.6 0.0 0.14 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RUS70113.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 RUS70113.1 - 0.091 12.5 0.3 0.16 11.7 0.1 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_5 PF13444.6 RUS70113.1 - 0.11 13.3 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3188 PF11384.8 RUS70113.1 - 2.1 8.1 5.5 7.3 6.4 5.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Pkinase PF00069.25 RUS70114.1 - 1.5e-30 106.5 0.1 1.7e-26 93.2 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70114.1 - 1.1e-18 67.5 0.0 2.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Formyl_trans_N PF00551.19 RUS70114.1 - 0.0059 16.4 0.6 21 4.8 0.0 3.2 3 0 0 3 3 3 2 Formyl transferase APH PF01636.23 RUS70114.1 - 0.01 15.8 0.2 0.7 9.8 0.7 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1951 PF09188.10 RUS70114.1 - 0.014 15.4 0.9 3.4 7.7 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1951) Utp12 PF04003.12 RUS70114.1 - 0.092 13.1 6.0 7.5 6.9 0.1 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family Dicer_N PF17895.1 RUS70114.1 - 0.1 12.5 0.1 31 4.4 0.0 2.9 3 0 0 3 3 3 0 Giardia Dicer N-terminal domain Pkinase_Tyr PF07714.17 RUS70115.1 - 5.1e-05 22.7 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS70115.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MRP_L53 PF10780.9 RUS70117.1 - 4.2e-07 30.1 0.0 6.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 FANCI_S4 PF14678.6 RUS70118.1 - 0.048 12.8 0.1 0.048 12.8 0.1 2.0 2 0 0 2 2 2 0 FANCI solenoid 4 FA_desaturase PF00487.24 RUS70122.1 - 1.1e-38 133.5 22.3 1.1e-38 133.5 22.3 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 RUS70122.1 - 5.1e-16 58.6 0.1 9.6e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Adap_comp_sub PF00928.21 RUS70123.1 - 9e-31 107.2 0.9 1.4e-30 106.6 0.9 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS70123.1 - 2.1e-06 27.7 0.5 2.1e-06 27.7 0.5 1.7 1 1 1 2 2 2 1 Clathrin adaptor complex small chain Lectin_C PF00059.21 RUS70124.1 - 1.2e-15 58.2 0.0 1.8e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Cep57_MT_bd PF06657.13 RUS70125.1 - 0.15 12.5 2.9 1.6 9.2 0.1 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF412 PF04217.13 RUS70125.1 - 0.32 10.9 1.2 17 5.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Myb_DNA-bind_3 PF12776.7 RUS70125.1 - 0.34 11.9 1.9 3 8.9 0.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Amino_oxidase PF01593.24 RUS70126.1 - 3.7e-14 52.9 0.0 6.3e-12 45.5 0.0 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS70126.1 - 2.9e-12 46.6 0.1 6e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS70126.1 - 8.2e-05 22.3 4.4 0.0011 18.6 2.4 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS70126.1 - 0.00086 18.6 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS70126.1 - 0.0014 18.6 0.3 0.0085 16.1 0.3 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 RUS70126.1 - 0.014 15.6 0.0 0.041 14.2 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 RUS70126.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS70126.1 - 0.45 11.1 1.7 48 4.6 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Drc1-Sld2 PF11719.8 RUS70127.1 - 0.017 14.7 0.8 0.017 14.7 0.8 2.6 1 1 1 2 2 2 0 DNA replication and checkpoint protein GRP PF07172.11 RUS70127.1 - 0.071 13.8 3.0 0.19 12.5 3.0 1.7 1 0 0 1 1 1 0 Glycine rich protein family RhoGAP PF00620.27 RUS70128.1 - 2.3e-38 131.4 0.2 8.3e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain SusD-like PF12741.7 RUS70129.1 - 0.0016 17.4 0.0 1.3 7.8 0.0 2.0 2 0 0 2 2 2 2 Susd and RagB outer membrane lipoprotein COP-gamma_platf PF08752.10 RUS70129.1 - 0.019 15.1 0.0 6.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain SabA_adhesion PF18304.1 RUS70129.1 - 0.02 14.2 0.0 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 SabA N-terminal extracellular adhesion domain DUF3145 PF11343.8 RUS70129.1 - 0.055 13.0 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) cwf21 PF08312.12 RUS70129.1 - 0.061 13.5 0.0 21 5.4 0.0 2.6 2 2 0 2 2 2 0 cwf21 domain Thionin PF00321.17 RUS70129.1 - 0.096 13.2 1.4 21 5.7 0.0 2.8 3 0 0 3 3 3 0 Plant thionin 5_3_exonuc_N PF02739.16 RUS70129.1 - 0.17 11.7 0.0 19 5.1 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain RIIa PF02197.17 RUS70129.1 - 0.51 10.1 2.7 13 5.6 0.0 3.4 4 0 0 4 4 4 0 Regulatory subunit of type II PKA R-subunit DD_K PF12121.8 RUS70129.1 - 0.77 9.9 2.3 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Dermaseptin LRR_8 PF13855.6 RUS70130.1 - 3.8e-28 97.0 27.8 1.4e-12 47.2 4.2 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS70130.1 - 5.9e-09 36.1 14.8 6.3e-07 29.6 4.1 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS70130.1 - 4.4e-05 23.5 12.9 5.3 8.0 0.0 5.0 5 0 0 5 5 4 0 Leucine Rich Repeat LMBR1 PF04791.16 RUS70130.1 - 0.00012 21.2 1.5 0.00015 20.8 1.5 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein SpoIIP PF07454.11 RUS70130.1 - 0.00038 20.0 1.8 0.00058 19.4 1.8 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 RUS70130.1 - 0.0054 15.1 7.8 0.0069 14.7 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF5427 PF10310.9 RUS70130.1 - 0.0072 15.3 6.0 0.0088 15.1 6.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF4407 PF14362.6 RUS70130.1 - 0.013 14.8 4.8 0.02 14.2 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 RUS70130.1 - 0.026 14.7 0.7 0.029 14.5 0.7 1.2 1 0 0 1 1 1 0 DDHD domain CAF1 PF04857.20 RUS70130.1 - 0.041 13.0 1.5 0.055 12.6 1.5 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease SUR7 PF06687.12 RUS70130.1 - 0.045 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 SUR7/PalI family NPR3 PF03666.13 RUS70130.1 - 0.049 12.4 7.6 0.068 12.0 7.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ALMT PF11744.8 RUS70130.1 - 0.064 12.1 3.9 0.084 11.7 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4337 PF14235.6 RUS70130.1 - 0.078 13.1 5.8 0.13 12.4 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.19 RUS70130.1 - 0.084 10.8 4.0 0.084 10.8 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 RUS70130.1 - 0.13 12.2 1.5 0.2 11.7 1.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALC PF17527.2 RUS70130.1 - 0.28 10.8 16.0 0.067 12.8 4.0 2.5 1 1 1 2 2 2 0 Phage ALC protein CobT PF06213.12 RUS70130.1 - 0.37 10.1 16.5 0.51 9.7 16.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_S49_N PF08496.10 RUS70130.1 - 0.43 10.6 17.5 0.23 11.5 15.2 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal VIT1 PF01988.19 RUS70130.1 - 0.6 9.9 1.7 0.92 9.3 1.7 1.2 1 0 0 1 1 1 0 VIT family LCD1 PF09798.9 RUS70130.1 - 0.93 7.9 10.3 1.2 7.6 10.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2072 PF09845.9 RUS70130.1 - 1.2 9.4 9.7 1.9 8.8 9.7 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF3899 PF13038.6 RUS70130.1 - 2.4 8.7 0.0 2.4 8.7 0.0 2.3 1 1 1 2 2 1 0 Domain of unknown function (DUF3899) PBP1_TM PF14812.6 RUS70130.1 - 2.8 8.4 14.4 0.16 12.4 3.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3391 PF11871.8 RUS70130.1 - 4.5 7.8 12.8 7.4 7.1 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Connexin PF00029.19 RUS70130.1 - 5.2 6.8 13.5 8.7 6.0 13.5 1.4 1 1 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 RUS70130.1 - 5.4 6.8 15.6 7.5 6.3 15.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_6 PF13516.6 RUS70130.1 - 5.8 7.2 16.6 2.8 8.2 0.2 4.7 5 0 0 5 5 5 0 Leucine Rich repeat MDM10 PF12519.8 RUS70130.1 - 5.9 5.6 6.5 7.8 5.2 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5401 PF17380.2 RUS70130.1 - 6.7 4.6 23.0 8.8 4.3 23.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Borrelia_P83 PF05262.11 RUS70130.1 - 7 5.0 20.0 9.2 4.6 20.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atrophin-1 PF03154.15 RUS70130.1 - 7 4.8 19.1 9.2 4.4 19.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family AAA_11 PF13086.6 RUS70130.1 - 7 6.3 13.0 10 5.8 13.0 1.2 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.8 RUS70130.1 - 10 4.9 18.6 14 4.5 18.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GMC_oxred_C PF05199.13 RUS70131.1 - 6.9e-41 140.1 0.0 8.8e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Nucleos_tra2_C PF07662.13 RUS70132.1 - 1.4e-72 243.9 7.6 1.7e-72 243.6 7.6 1.1 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Phage_holin_2_1 PF04971.12 RUS70132.1 - 4 7.5 5.6 48 4.1 0.4 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S RNA_GG_bind PF10258.9 RUS70133.1 - 2e-28 98.3 0.0 4.1e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain Sigma_reg_N PF13800.6 RUS70134.1 - 0.018 15.3 1.8 0.027 14.8 0.5 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ODV-E18 PF10717.9 RUS70134.1 - 0.13 12.2 0.7 0.34 10.8 0.7 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2417 PF10329.9 RUS70134.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) MORN PF02493.20 RUS70135.1 - 8.3e-12 44.3 5.4 1.5e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 MORN repeat MCM_bind PF09739.9 RUS70136.1 - 1.2e-160 535.8 0.0 1.5e-160 535.5 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Flg_bbr_C PF06429.13 RUS70136.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal HEAT_EZ PF13513.6 RUS70137.1 - 1.3e-15 57.5 0.0 0.00068 20.1 0.0 7.0 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.22 RUS70137.1 - 1.3e-14 53.0 2.3 0.00021 21.3 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 RUS70137.1 - 3.2e-12 46.7 0.0 1.2e-05 25.6 0.0 5.6 4 2 3 7 7 7 3 HEAT repeats Importin_rep_6 PF18829.1 RUS70137.1 - 9.2e-10 38.6 2.0 6.6e-09 35.9 0.1 2.9 2 1 1 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 RUS70137.1 - 2.4e-09 37.6 3.0 0.0061 17.1 0.0 6.4 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RUS70137.1 - 2.6e-09 37.3 1.1 3.6e-06 27.1 0.1 3.4 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 RUS70137.1 - 9.3e-06 25.6 0.0 0.53 10.2 0.0 5.1 2 1 1 4 4 4 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 RUS70137.1 - 0.00016 21.5 0.0 0.97 9.1 0.0 4.3 3 2 2 5 5 5 1 rRNA processing/ribosome biogenesis Importin_rep_5 PF18816.1 RUS70137.1 - 0.00032 20.9 0.1 0.0021 18.3 0.0 2.5 2 0 0 2 2 1 1 Importin repeat Adaptin_N PF01602.20 RUS70137.1 - 0.00059 18.5 1.6 0.0016 17.1 0.2 2.2 2 0 0 2 2 2 1 Adaptin N terminal region MMS19_N PF14500.6 RUS70137.1 - 0.00086 19.0 0.2 1.9 8.0 0.0 3.9 4 2 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_PBS PF03130.16 RUS70137.1 - 0.0023 18.5 0.7 2.1 9.2 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Tti2 PF10521.9 RUS70137.1 - 0.0068 16.0 0.0 0.042 13.4 0.0 2.5 3 1 0 3 3 3 1 Tti2 family Arm PF00514.23 RUS70137.1 - 0.012 15.7 0.2 21 5.3 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 RUS70137.1 - 0.013 15.3 2.2 0.052 13.3 0.0 3.2 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) TAF6_C PF07571.13 RUS70137.1 - 0.034 14.5 0.0 0.15 12.4 0.0 2.2 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain BP28CT PF08146.12 RUS70137.1 - 0.04 13.8 0.9 2.6 7.8 0.1 3.4 3 0 0 3 3 3 0 BP28CT (NUC211) domain RNase_H PF00075.24 RUS70140.1 - 2.8e-07 30.8 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNase H PMP22_Claudin PF00822.20 RUS70141.1 - 1.4e-07 31.5 5.9 1.8e-07 31.2 5.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS70141.1 - 6.5e-07 29.3 8.1 2.3e-05 24.2 3.5 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS70141.1 - 1.5e-06 28.3 7.2 2.8e-06 27.4 7.2 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Amastin PF07344.11 RUS70141.1 - 0.00076 19.3 4.1 0.0011 18.9 3.5 1.5 1 1 0 1 1 1 1 Amastin surface glycoprotein Atthog PF18800.1 RUS70141.1 - 0.037 13.9 5.5 0.045 13.6 4.8 1.5 1 1 0 1 1 1 0 Attenuator of Hedgehog SCAMP PF04144.13 RUS70141.1 - 2.3 8.5 7.5 0.18 12.1 2.5 1.7 2 0 0 2 2 2 0 SCAMP family Trypsin_2 PF13365.6 RUS70142.1 - 1.6e-08 35.6 0.2 6e-08 33.7 0.1 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Ank_2 PF12796.7 RUS70143.1 - 1.3e-09 38.5 0.0 6.6e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS70143.1 - 1.2e-07 31.8 0.0 0.0093 16.4 0.0 3.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RUS70143.1 - 3.6e-07 30.0 0.1 0.00046 20.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 RUS70143.1 - 6.9e-05 23.0 0.2 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS70143.1 - 0.0051 17.1 0.1 0.0051 17.1 0.1 2.7 2 0 0 2 2 2 1 SOCS box Ank_4 PF13637.6 RUS70143.1 - 0.011 16.2 0.0 0.23 12.1 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Somatomedin_B PF01033.17 RUS70144.1 - 0.0007 19.9 12.7 0.0007 19.9 12.7 2.3 2 0 0 2 2 2 1 Somatomedin B domain bPH_3 PF14470.6 RUS70146.1 - 0.0073 16.6 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 RUS70146.1 - 0.024 14.8 0.1 0.053 13.7 0.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 KORA PF16509.5 RUS70146.1 - 0.1 12.9 0.4 0.77 10.1 0.1 2.2 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor GRAM PF02893.20 RUS70146.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain dDENN PF03455.19 RUS70147.1 - 2e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 dDENN domain DENN PF02141.21 RUS70148.1 - 1.9e-37 129.1 5.4 2.8e-37 128.5 5.4 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RUS70148.1 - 8.9e-10 39.2 0.8 1.2e-08 35.6 0.1 2.5 2 0 0 2 2 2 1 uDENN domain ShK PF01549.24 RUS70149.1 - 3.4e-06 27.5 26.0 0.0041 17.6 5.0 4.8 3 0 0 3 3 3 3 ShK domain-like DNA_pol_phi PF04931.13 RUS70149.1 - 0.42 8.7 53.2 0.59 8.2 53.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS70149.1 - 2 6.5 39.7 3.4 5.8 39.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS70149.1 - 4.1 6.6 35.2 10 5.3 35.2 1.6 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.8 RUS70151.1 - 0.17 10.6 1.8 0.21 10.3 1.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.18 RUS70151.1 - 8.8 4.9 7.4 12 4.5 7.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier adh_short PF00106.25 RUS70152.1 - 2.5e-42 144.6 0.0 3.3e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS70152.1 - 1.3e-26 93.7 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS70152.1 - 3e-06 27.3 0.1 5.4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RUS70152.1 - 7.1e-06 25.6 0.0 9.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HMG_box PF00505.19 RUS70152.1 - 0.19 12.1 0.1 0.38 11.2 0.1 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box DUF2283 PF10049.9 RUS70153.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) 7TM_GPCR_Srw PF10324.9 RUS70154.1 - 3.2e-18 66.1 12.8 4.3e-18 65.7 12.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS70154.1 - 3.8e-18 65.8 11.4 4.7e-18 65.4 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70154.1 - 6e-10 39.2 7.6 6e-10 39.2 7.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 RUS70154.1 - 0.00049 19.7 7.2 0.00049 19.7 7.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srsx PF10320.9 RUS70154.1 - 0.003 17.0 14.2 0.035 13.5 14.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Bac_surface_Ag PF01103.23 RUS70155.1 - 8.2e-44 150.4 1.8 1e-43 150.1 1.8 1.1 1 0 0 1 1 1 1 Surface antigen Mito_fiss_reg PF05308.11 RUS70156.1 - 2.6 8.0 34.2 0.073 13.2 10.8 3.5 3 0 0 3 3 3 0 Mitochondrial fission regulator Castor1_N PF18700.1 RUS70157.1 - 0.055 13.3 7.6 2.6 7.9 0.8 3.6 1 1 1 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Imm48 PF15574.6 RUS70157.1 - 3.9 7.3 4.5 1.2 8.9 0.6 2.0 2 0 0 2 2 2 0 Immunity protein 48 Forkhead PF00250.18 RUS70158.1 - 1e-34 118.6 0.1 2.3e-34 117.5 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Ribonuc_L-PSP PF01042.21 RUS70159.1 - 0.12 12.4 0.0 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 RUS70160.1 - 8.5e-44 149.7 0.1 1.6e-43 148.8 0.1 1.4 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 RUS70160.1 - 3.5e-08 33.5 0.0 5.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP QueC PF06508.13 RUS70160.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Golgin_A5 PF09787.9 RUS70161.1 - 9.2e-29 100.9 20.4 9.2e-29 100.9 20.4 3.2 1 1 2 3 3 3 2 Golgin subfamily A member 5 Caskin-tail PF16632.5 RUS70161.1 - 0.18 12.3 13.5 0.5 10.8 2.9 3.9 3 0 0 3 3 3 0 C-terminal region of Caskin TPR_MLP1_2 PF07926.12 RUS70161.1 - 0.21 11.7 69.3 0.35 10.9 15.5 3.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 RUS70161.1 - 3 8.0 34.5 2.2 8.5 6.1 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 RUS70161.1 - 9.5 4.3 40.6 0.098 10.8 11.3 3.0 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Ig_3 PF13927.6 RUS70162.1 - 9.4e-20 71.0 0.2 5e-11 43.0 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS70162.1 - 5.6e-19 68.0 0.0 7.5e-08 32.3 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS70162.1 - 1e-14 54.5 0.0 1.2e-06 28.5 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS70162.1 - 6.2e-14 52.1 0.1 7.3e-06 26.1 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS70162.1 - 4.1e-09 36.7 0.1 9.4e-05 22.7 0.0 3.4 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS70162.1 - 0.00044 20.3 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS70162.1 - 0.09 12.9 0.1 24 5.1 0.0 2.8 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF2358 PF10184.9 RUS70163.1 - 1.1e-13 51.4 0.9 4.4e-13 49.5 0.6 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) DSPc PF00782.20 RUS70164.1 - 6.8e-26 90.7 0.0 9e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS70164.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RUS70164.1 - 0.045 14.0 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 RUS70164.1 - 0.24 11.5 0.0 0.37 10.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate RVT_1 PF00078.27 RUS70165.1 - 1.6e-17 63.8 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AT_hook PF02178.19 RUS70165.1 - 0.043 13.7 2.0 0.16 11.9 2.0 2.0 1 0 0 1 1 1 0 AT hook motif Imm42 PF15593.6 RUS70166.1 - 0.0032 18.0 4.4 14 6.1 0.1 3.9 1 1 3 4 4 4 3 Immunity protein 42 LRR_5 PF13306.6 RUS70166.1 - 0.43 10.6 8.8 0.48 10.4 8.8 1.0 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF2109 PF09882.9 RUS70166.1 - 0.58 10.2 4.6 0.57 10.2 1.2 2.2 1 1 1 3 3 3 0 Predicted membrane protein (DUF2109) TFIIIC_sub6 PF10419.9 RUS70166.1 - 7.7 6.5 9.4 1.2e+02 2.7 0.1 4.1 2 1 2 4 4 4 0 TFIIIC subunit triple barrel domain Laminin_G_2 PF02210.24 RUS70167.1 - 6.3e-13 49.4 0.0 8.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS70167.1 - 9.6e-10 38.8 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain HTH_32 PF13565.6 RUS70171.1 - 0.00051 20.6 0.1 0.00068 20.2 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 RUS70171.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF4817 PF16087.5 RUS70171.1 - 0.022 14.6 0.0 0.061 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) MFS_1 PF07690.16 RUS70172.1 - 4.8e-33 114.5 65.4 1e-16 60.8 23.2 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS70172.1 - 0.068 12.0 38.8 0.33 9.8 0.1 3.9 3 1 0 3 3 3 0 Sugar (and other) transporter SHR3_chaperone PF08229.11 RUS70172.1 - 5 6.1 10.2 80 2.1 10.2 2.4 1 1 0 1 1 1 0 ER membrane protein SH3 Ig_3 PF13927.6 RUS70173.1 - 1.5e-24 86.4 0.0 1.1e-07 32.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS70173.1 - 1.8e-23 82.4 0.0 1.7e-07 31.2 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RUS70173.1 - 8.8e-16 57.9 0.0 3.7e-05 23.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS70173.1 - 1.9e-11 44.1 0.4 1.3e-05 25.3 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS70173.1 - 1.1e-10 41.7 0.1 0.00041 20.6 0.0 4.0 3 2 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 RUS70173.1 - 0.0017 18.4 0.1 0.45 10.6 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain MFS_1 PF07690.16 RUS70174.1 - 4.9e-15 55.3 34.6 1.1e-11 44.3 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS70174.1 - 1.1e-05 24.5 12.8 1.7e-05 23.9 12.8 1.2 1 0 0 1 1 1 1 MFS_1 like family DUF3450 PF11932.8 RUS70175.1 - 0.61 9.4 16.6 1 8.6 16.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RNA_polI_A14 PF08203.11 RUS70175.1 - 0.99 10.2 10.1 0.64 10.8 1.7 3.3 2 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Mit_KHE1 PF10173.9 RUS70175.1 - 1.4 9.0 6.3 2.2 8.3 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TetR_C_14 PF17754.1 RUS70175.1 - 1.6 8.7 6.5 1.7 8.6 0.4 2.9 1 1 1 2 2 2 0 MftR C-terminal domain DUF4407 PF14362.6 RUS70175.1 - 2.3 7.5 12.1 3.8 6.8 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 RUS70175.1 - 9.2 6.0 24.5 42 3.8 24.5 1.9 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B FlxA PF14282.6 RUS70177.1 - 0.018 15.0 6.5 1.4 9.0 6.2 2.8 2 0 0 2 2 2 0 FlxA-like protein T6PP_N PF18572.1 RUS70177.1 - 0.37 10.6 5.6 0.14 12.0 1.9 2.2 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Vps51 PF08700.11 RUS70177.1 - 0.61 10.2 6.9 0.33 11.1 3.7 2.2 2 0 0 2 2 2 0 Vps51/Vps67 DUF724 PF05266.14 RUS70177.1 - 1.8 8.3 17.5 0.43 10.4 6.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 RUS70177.1 - 2.5 7.7 21.6 0.043 13.5 7.6 2.7 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Sec8_exocyst PF04048.14 RUS70177.1 - 3.8 7.4 11.7 2.2 8.2 3.7 3.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Tho2 PF11262.8 RUS70177.1 - 5.8 6.0 9.0 1.3 8.1 4.8 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 SlyX PF04102.12 RUS70177.1 - 6.4 7.5 12.5 56 4.4 7.3 3.9 3 2 1 4 4 4 0 SlyX XhlA PF10779.9 RUS70177.1 - 7.9 6.8 11.7 42 4.4 0.0 3.8 3 1 0 3 3 3 0 Haemolysin XhlA KxDL PF10241.9 RUS70177.1 - 8 6.8 10.9 0.95 9.8 4.4 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein Collagen PF01391.18 RUS70179.1 - 0.54 10.1 22.4 1.1 9.1 22.4 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF229 PF02995.17 RUS70180.1 - 3.4e-92 309.6 0.0 6.8e-92 308.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS70180.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS70180.1 - 0.015 14.9 0.1 0.042 13.4 0.1 1.7 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 RUS70180.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cyclin_C PF02984.19 RUS70180.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Lectin_C PF00059.21 RUS70181.1 - 5.7e-14 52.8 0.1 5.7e-14 52.8 0.1 1.5 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 RUS70181.1 - 0.0042 17.0 0.4 0.011 15.6 0.4 1.8 1 0 0 1 1 1 1 PAN domain DUF169 PF02596.15 RUS70181.1 - 0.071 13.0 0.2 0.83 9.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 Ribosomal_TL5_C PF14693.6 RUS70182.1 - 0.011 16.1 14.2 22 5.5 0.3 6.4 2 2 3 5 5 5 0 Ribosomal protein TL5, C-terminal domain Adeno_E1B_19K PF01691.16 RUS70182.1 - 0.047 13.2 1.9 74 2.9 0.0 4.5 1 1 3 6 6 6 0 Adenovirus E1B 19K protein / small t-antigen NPM1-C PF16276.5 RUS70182.1 - 1 9.4 5.3 79 3.3 0.0 5.5 3 3 6 10 10 10 0 Nucleophosmin C-terminal domain YbjQ_1 PF01906.17 RUS70183.1 - 1.1e-05 26.0 20.9 1.2 9.9 0.2 6.4 1 1 6 7 7 7 7 Putative heavy-metal-binding Adeno_E3_15_3 PF03307.14 RUS70183.1 - 0.11 12.5 23.9 6 6.9 1.0 6.6 1 1 8 9 9 9 0 Adenovirus 15.3kD protein in E3 region BRICHOS PF04089.14 RUS70185.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain Ependymin PF00811.18 RUS70185.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Ependymin DUF5104 PF17117.5 RUS70185.1 - 0.052 14.0 0.1 4.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Ribosomal_60s PF00428.19 RUS70186.1 - 0.016 15.8 1.8 0.058 14.0 1.8 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.14 RUS70186.1 - 0.73 8.1 9.6 1.1 7.4 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS70186.1 - 2.5 7.3 6.8 4.7 6.5 6.8 1.4 1 0 0 1 1 1 0 NOA36 protein ALMT PF11744.8 RUS70186.1 - 2.9 6.6 5.8 4.2 6.1 5.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PTPRCAP PF15713.5 RUS70186.1 - 4.8 7.5 17.4 0.2 11.9 10.4 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated F-box PF00646.33 RUS70188.1 - 3.6e-09 36.3 0.3 9.2e-09 35.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS70188.1 - 9.4e-06 25.4 2.5 1e-05 25.3 1.2 1.7 1 1 0 1 1 1 1 F-box-like Beta_helix PF13229.6 RUS70190.1 - 2.3e-39 134.8 37.1 1.1e-20 74.1 14.7 3.1 2 1 1 3 3 3 3 Right handed beta helix region NosD PF05048.13 RUS70190.1 - 6.2e-23 81.3 26.4 2.1e-08 33.7 7.7 3.9 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Asparaginase_C PF17763.1 RUS70190.1 - 2.7 8.2 5.0 6.5 7.0 0.1 3.4 3 1 1 4 4 4 0 Glutaminase/Asparaginase C-terminal domain Pre-PUA PF17832.1 RUS70191.1 - 8.4e-25 87.3 3.4 2.1e-24 86.0 0.4 2.6 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 RUS70191.1 - 5e-20 71.8 1.3 5e-20 71.8 1.3 2.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.20 RUS70191.1 - 7.3e-06 25.9 0.0 2.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 PUA domain SWIB PF02201.18 RUS70191.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain DUF1947 PF09183.10 RUS70191.1 - 0.065 13.5 1.3 0.46 10.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Kin17_mid PF10357.9 RUS70191.1 - 0.26 11.2 0.8 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein CENP-B_dimeris PF09026.10 RUS70191.1 - 7.7 7.0 10.3 0.28 11.6 2.1 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Keratin_2_head PF16208.5 RUS70192.1 - 0.015 15.5 8.9 0.015 15.5 8.9 3.3 2 1 0 3 3 3 0 Keratin type II head Keratin_2_head PF16208.5 RUS70193.1 - 0.005 17.0 8.3 0.005 17.0 8.3 2.1 2 0 0 2 2 2 1 Keratin type II head KRTAP PF11759.8 RUS70193.1 - 0.022 15.3 8.7 0.022 15.3 8.7 2.3 2 0 0 2 2 2 0 Keratin-associated matrix Cwf_Cwc_15 PF04889.12 RUS70193.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Arf PF00025.21 RUS70194.1 - 3.1e-67 225.4 0.0 8.8e-67 223.9 0.0 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS70194.1 - 3.4e-15 56.0 0.0 7.4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70194.1 - 4e-15 56.1 0.1 8.9e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS70194.1 - 1.5e-11 44.0 0.1 5.3e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS70194.1 - 1.3e-10 40.9 3.9 8.4e-10 38.3 3.9 2.6 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS70194.1 - 3.7e-08 33.0 0.0 9.6e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-B_box PF00643.24 RUS70194.1 - 4.3e-07 30.0 6.2 4.3e-07 30.0 6.2 5.1 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 RUS70194.1 - 5.3e-05 23.1 7.1 5.3e-05 23.1 7.1 3.9 4 0 0 4 4 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS70194.1 - 0.001 19.1 9.5 0.001 19.1 9.5 3.4 5 0 0 5 5 5 1 RING-type zinc-finger MMR_HSR1 PF01926.23 RUS70194.1 - 0.0014 18.7 0.0 0.0045 17.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_2 PF13639.6 RUS70194.1 - 0.004 17.4 7.6 0.004 17.4 7.6 4.4 4 1 1 5 5 4 1 Ring finger domain LURAP PF14854.6 RUS70194.1 - 0.045 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF883 PF05957.13 RUS70194.1 - 0.25 12.0 4.3 15 6.3 0.2 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 RUS70194.1 - 1.7 8.7 7.2 4.7 7.3 0.2 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) PLU-1 PF08429.11 RUS70195.1 - 0.1 11.8 0.8 0.14 11.3 0.8 1.1 1 0 0 1 1 1 0 PLU-1-like protein GST_N_3 PF13417.6 RUS70196.1 - 7.1e-18 64.8 0.1 1.2e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS70196.1 - 3.7e-14 52.8 0.0 6.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS70196.1 - 2.5e-12 46.9 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS70196.1 - 1.9e-08 34.4 0.0 3.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS70196.1 - 5.4e-05 23.3 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS70196.1 - 0.0021 18.0 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4764 PF15961.5 RUS70198.1 - 5.3e-39 134.6 0.3 9.9e-39 133.7 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 RUS70198.1 - 0.0066 16.8 0.4 0.0066 16.8 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS70198.1 - 0.035 14.4 1.4 0.057 13.7 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS70198.1 - 6.2 7.4 7.4 3.2 8.3 0.6 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Ig_3 PF13927.6 RUS70199.1 - 0.0031 18.1 0.0 0.015 15.9 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS70199.1 - 0.0034 17.7 0.3 0.33 11.3 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain Aminotran_3 PF00202.21 RUS70201.1 - 7.1e-78 262.0 0.0 9.2e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.25 RUS70202.1 - 1.6e-40 139.1 0.0 2.5e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70202.1 - 7.6e-38 130.3 0.0 1.4e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TBCC PF07986.12 RUS70202.1 - 0.044 13.5 1.8 0.099 12.4 1.8 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C DUF459 PF04311.13 RUS70202.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) TPR_7 PF13176.6 RUS70203.1 - 6.9e-07 28.9 2.1 0.74 10.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70203.1 - 7.1e-06 26.2 0.7 0.024 14.9 0.6 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS70203.1 - 5.4e-05 23.0 0.2 4.4 7.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS70203.1 - 0.00018 21.2 0.2 8.2 6.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS70203.1 - 0.00018 22.0 1.9 8.7 7.5 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70203.1 - 0.002 18.2 0.6 1.6 9.1 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS70203.1 - 0.0039 17.7 2.0 7.8 7.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5645 PF18713.1 RUS70203.1 - 0.018 15.3 0.7 0.035 14.4 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5645) TPR_19 PF14559.6 RUS70203.1 - 0.021 15.3 0.2 4.1 8.0 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat BBP1_N PF15271.6 RUS70203.1 - 0.035 14.9 0.4 0.051 14.4 0.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein SNAP PF14938.6 RUS70203.1 - 0.043 13.2 1.1 0.34 10.3 0.0 2.3 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 RUS70203.1 - 0.082 13.0 2.6 0.98 9.5 0.0 3.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 RUS70203.1 - 0.093 12.4 0.2 44 3.9 0.0 3.2 3 0 0 3 3 3 0 TPR repeat GlutR_dimer PF00745.20 RUS70203.1 - 0.095 13.2 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain ANAPC3 PF12895.7 RUS70203.1 - 0.11 12.7 1.8 1.2 9.5 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RUS70203.1 - 0.12 13.1 0.1 53 4.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0542 PF15086.6 RUS70204.1 - 6.8 6.7 8.5 10 6.1 8.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 EF-hand_7 PF13499.6 RUS70205.1 - 8.2e-20 71.0 4.1 1.3e-12 48.0 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS70205.1 - 1.8e-18 64.6 6.2 3.7e-07 29.2 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS70205.1 - 2.3e-15 55.1 5.6 0.0004 20.1 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS70205.1 - 1.8e-12 46.9 7.7 1.8e-09 37.3 0.1 4.3 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS70205.1 - 3.8e-09 35.6 12.1 0.00011 21.6 0.3 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 RUS70205.1 - 8.7e-06 26.0 0.2 0.0043 17.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 RUS70205.1 - 0.0015 18.8 0.5 0.34 11.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RUS70205.1 - 0.0018 19.1 0.0 0.0036 18.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Dockerin_1 PF00404.18 RUS70205.1 - 0.0041 17.3 0.1 0.027 14.7 0.0 2.2 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 RUS70205.1 - 0.014 15.4 1.6 0.11 12.4 0.1 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Frankia_peptide PF14407.6 RUS70205.1 - 0.036 14.0 0.1 7.4 6.6 0.0 3.0 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. SPARC_Ca_bdg PF10591.9 RUS70205.1 - 0.15 12.4 0.1 5.6 7.3 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1647 PF07801.11 RUS70206.1 - 2.7e-09 36.9 0.0 6.4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Gp_dh_C PF02800.20 RUS70207.1 - 3.9e-70 234.5 0.0 6.2e-70 233.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RUS70207.1 - 1.8e-36 124.5 0.0 5.7e-36 122.9 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS70207.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 RUS70207.1 - 0.012 15.5 0.5 0.9 9.4 0.1 2.4 2 0 0 2 2 2 0 Rossmann-like domain FAT PF02259.23 RUS70208.1 - 2.8e-114 381.9 3.0 2.8e-114 381.9 3.0 2.4 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 RUS70208.1 - 3.2e-61 205.9 11.3 7.6e-55 185.2 0.3 4.8 5 0 0 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 RUS70208.1 - 7.1e-43 145.1 0.3 7.1e-43 145.1 0.3 3.2 2 1 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 RUS70208.1 - 1.7e-11 44.4 8.5 0.29 11.6 0.0 8.4 7 2 3 10 10 8 3 HEAT repeats HEAT PF02985.22 RUS70208.1 - 4.4e-11 42.0 8.5 0.00034 20.6 0.0 9.2 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 RUS70208.1 - 3.2e-07 30.7 16.4 3.7 8.2 0.0 10.9 11 2 2 13 13 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RUS70208.1 - 1.1e-06 29.1 4.6 2.1 9.0 0.4 7.4 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 RUS70208.1 - 2.2e-05 24.2 11.3 0.99 8.9 1.6 6.2 2 1 2 5 5 5 2 Tti2 family Sec7_N PF12783.7 RUS70208.1 - 0.00024 21.0 3.7 9.5 6.1 0.0 5.2 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal CLASP_N PF12348.8 RUS70208.1 - 0.0033 17.0 0.8 32 4.0 0.0 5.4 4 0 0 4 4 4 0 CLASP N terminal IFRD PF05004.13 RUS70208.1 - 0.012 14.8 0.0 0.53 9.3 0.0 3.4 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) UME PF08064.13 RUS70208.1 - 0.056 13.4 14.8 13 5.8 0.2 6.7 7 1 1 8 8 8 0 UME (NUC010) domain RICTOR_V PF14668.6 RUS70208.1 - 0.11 12.8 0.1 2.9 8.2 0.0 3.4 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 TPR_19 PF14559.6 RUS70208.1 - 0.13 12.7 1.9 13 6.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Dopey_N PF04118.14 RUS70208.1 - 0.67 9.0 7.5 3.2 6.8 0.3 4.3 4 0 0 4 4 4 0 Dopey, N-terminal FANCI_S1 PF14675.6 RUS70208.1 - 2.2 7.8 6.6 3.6 7.1 0.2 4.0 4 0 0 4 4 4 0 FANCI solenoid 1 MFS_1 PF07690.16 RUS70209.1 - 1.5e-06 27.4 0.4 1.8e-06 27.1 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0060 PF02694.15 RUS70209.1 - 0.0032 17.7 0.6 0.0053 17.0 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family Glucos_trans_II PF14264.6 RUS70209.1 - 0.23 10.8 4.8 0.25 10.7 0.1 2.0 1 1 1 2 2 2 0 Glucosyl transferase GtrII Bax1-I PF01027.20 RUS70209.1 - 0.71 9.7 5.2 1.2 8.9 5.2 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4523 PF15023.6 RUS70210.1 - 4.1e-08 33.2 0.0 5.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Aminotran_1_2 PF00155.21 RUS70213.1 - 2e-73 247.7 0.0 2.3e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RUS70213.1 - 1.5e-08 34.0 0.0 2.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 RUS70213.1 - 0.0002 20.3 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 RUS70213.1 - 0.00091 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RUS70213.1 - 0.0018 16.9 0.0 0.0032 16.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 RUS70213.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3512 PF12024.8 RUS70214.1 - 9.5e-61 205.3 2.3 9.5e-61 205.3 2.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 RUS70214.1 - 3.1e-19 68.8 0.9 6.3e-19 67.8 0.9 1.5 1 0 0 1 1 1 1 Bromodomain DUF4745 PF15923.5 RUS70215.1 - 0.016 15.2 0.2 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) PDGF PF00341.17 RUS70217.1 - 3.5e-07 30.4 2.6 1.1e-06 28.9 2.6 1.9 1 1 0 1 1 1 1 PDGF/VEGF domain Glug PF07581.12 RUS70217.1 - 0.14 12.6 11.3 1.6 9.3 0.0 4.2 4 0 0 4 4 4 0 The GLUG motif MFS_1 PF07690.16 RUS70218.1 - 3.9e-33 114.8 55.3 2.3e-30 105.7 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RanGAP1_C PF07834.11 RUS70219.1 - 9.5e-50 168.7 0.1 1.4e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 RanGAP1 C-terminal domain LRR_6 PF13516.6 RUS70219.1 - 4.5e-21 73.1 23.9 0.0097 15.9 0.1 9.3 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 RUS70219.1 - 1.3e-08 35.0 15.4 0.00017 21.9 1.1 4.6 3 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS70219.1 - 8.5e-08 31.7 2.7 13 6.8 0.0 6.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 RUS70219.1 - 0.00037 20.2 16.6 0.082 12.7 2.5 5.9 3 1 1 5 5 5 3 Leucine rich repeat Herpes_BTRF1 PF04682.12 RUS70219.1 - 0.19 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region tRNA_bind PF01588.20 RUS70220.1 - 8.9e-30 102.7 0.1 3.4e-28 97.6 0.1 2.5 2 0 0 2 2 2 1 Putative tRNA binding domain Cnn_1N PF07989.11 RUS70220.1 - 0.053 13.7 1.6 0.11 12.6 1.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF809 PF05663.11 RUS70220.1 - 0.58 10.3 2.8 1.3 9.1 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Pkinase PF00069.25 RUS70221.1 - 1.2e-40 139.6 0.0 6.3e-40 137.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70221.1 - 3.3e-20 72.4 0.0 5.7e-17 61.9 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS70221.1 - 6.1e-07 28.6 2.8 1.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS70221.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rad51 PF08423.11 RUS70222.1 - 1e-44 152.7 0.0 1.6e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 RUS70222.1 - 5.2e-08 32.7 0.0 0.001 18.6 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.6 RUS70222.1 - 6.1e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RUS70222.1 - 1.3e-06 27.9 0.1 5.5e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 RUS70222.1 - 1.8e-05 24.2 0.0 0.0026 17.1 0.0 2.3 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain AAA_22 PF13401.6 RUS70222.1 - 0.015 15.6 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 RUS70223.1 - 5.5e-75 252.1 0.0 7.9e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70223.1 - 5e-44 150.5 0.0 7.7e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 RUS70223.1 - 6.5e-20 70.7 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 RUS70223.1 - 5e-06 26.0 0.0 1.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS70223.1 - 0.0006 19.5 0.4 0.0011 18.6 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RUS70223.1 - 0.0045 16.0 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RUS70223.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.11 RUS70223.1 - 0.014 15.5 0.3 0.038 14.1 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YrbL-PhoP_reg PF10707.9 RUS70223.1 - 0.082 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UBA PF00627.31 RUS70223.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain LRR_8 PF13855.6 RUS70224.1 - 2.6e-67 222.5 59.9 2.8e-13 49.4 0.5 7.8 5 1 3 8 8 8 7 Leucine rich repeat I-set PF07679.16 RUS70224.1 - 2.8e-49 165.1 0.1 2.7e-22 78.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS70224.1 - 1.3e-47 160.3 4.5 1.5e-16 60.7 0.0 5.0 4 0 0 4 4 4 3 Immunoglobulin domain LRR_4 PF12799.7 RUS70224.1 - 2.3e-36 123.2 58.9 1.4e-07 31.7 0.3 10.0 5 2 5 11 11 11 11 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 RUS70224.1 - 5.7e-30 103.5 1.3 1.9e-11 44.1 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS70224.1 - 3.8e-29 100.7 1.1 4.9e-10 39.5 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 RUS70224.1 - 4.8e-27 94.4 1.3 2e-06 27.8 0.1 4.7 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS70224.1 - 4.5e-18 65.4 24.6 0.00014 21.4 2.5 6.1 1 1 5 6 6 6 6 Leucine-rich repeat V-set PF07686.17 RUS70224.1 - 5e-13 49.2 7.9 0.0029 17.8 0.3 6.3 3 3 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS70224.1 - 1e-10 41.5 0.4 0.0054 16.8 0.0 3.9 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RUS70224.1 - 1e-07 32.2 0.2 0.0099 16.2 0.0 4.0 3 1 0 3 3 3 2 Immunoglobulin C1-set domain LRR_1 PF00560.33 RUS70224.1 - 0.011 16.1 43.2 1.8 9.4 0.0 12.6 11 3 1 12 12 12 0 Leucine Rich Repeat PRIMA1 PF16101.5 RUS70224.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TMEM154 PF15102.6 RUS70224.1 - 0.31 10.9 1.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family LRR_6 PF13516.6 RUS70224.1 - 3.4 8.0 49.9 0.24 11.6 0.4 11.6 14 0 0 14 14 13 0 Leucine Rich repeat YjzC PF14168.6 RUS70225.1 - 0.0047 17.3 0.8 0.011 16.1 0.1 2.0 2 0 0 2 2 2 1 YjzC-like protein TIP49 PF06068.13 RUS70226.1 - 3.4e-172 572.5 0.8 4e-172 572.2 0.8 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain AAA PF00004.29 RUS70226.1 - 2.8e-12 47.2 0.2 1.7e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RUS70226.1 - 2.3e-11 43.7 0.3 1.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS70226.1 - 9.2e-07 29.2 0.4 0.019 15.2 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 RUS70226.1 - 5.7e-05 23.1 0.1 0.0045 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RUS70226.1 - 7.2e-05 22.4 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS70226.1 - 8.9e-05 22.9 0.1 0.00053 20.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 RUS70226.1 - 0.00013 21.8 0.1 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 RUS70226.1 - 0.00017 22.1 0.0 0.0056 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS70226.1 - 0.00064 20.1 3.1 0.012 15.9 3.1 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RUS70226.1 - 0.00095 18.6 0.3 0.049 13.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RUS70226.1 - 0.0013 18.7 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS70226.1 - 0.0033 17.2 0.1 0.0082 15.9 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 RUS70226.1 - 0.0042 17.3 0.1 0.0077 16.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RUS70226.1 - 0.0043 17.1 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaB_C PF03796.15 RUS70226.1 - 0.0068 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_7 PF12775.7 RUS70226.1 - 0.007 15.9 0.1 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 RUS70226.1 - 0.0085 15.4 0.2 0.025 13.8 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 RUS70226.1 - 0.0094 15.7 0.3 0.45 10.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RUS70226.1 - 0.011 15.6 0.1 0.027 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 RUS70226.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 RUS70226.1 - 0.017 14.6 0.9 0.045 13.2 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 RUS70226.1 - 0.027 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RUS70226.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.8 3 0 0 3 3 1 0 AAA domain DUF2075 PF09848.9 RUS70226.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RUS70226.1 - 0.044 13.1 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 RUS70226.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 RUS70226.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 RUS70226.1 - 0.14 12.6 1.7 1.1 9.7 0.0 2.8 2 1 0 3 3 3 0 AAA domain 7tm_1 PF00001.21 RUS70227.1 - 1.4e-54 185.2 9.3 2e-54 184.7 9.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70227.1 - 1.3e-09 38.1 19.5 2.2e-09 37.4 17.3 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS70227.1 - 0.022 14.5 13.6 0.037 13.7 13.6 1.3 1 0 0 1 1 1 0 Olfactory receptor CUB PF00431.20 RUS70228.1 - 4.1e-66 220.2 2.1 1.9e-18 66.8 0.1 5.0 5 0 0 5 5 5 5 CUB domain CUB_2 PF02408.20 RUS70228.1 - 0.011 15.5 4.2 0.3 10.8 0.4 3.1 3 0 0 3 3 3 0 CUB-like domain Peptidase_S10 PF00450.22 RUS70229.1 - 7.2e-63 213.4 0.0 1.5e-62 212.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 RUS70229.1 - 0.014 14.7 0.0 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4587 PF15248.6 RUS70230.1 - 3.3e-06 27.8 27.7 3.7e-06 27.6 21.6 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4587) QIL1 PF15884.5 RUS70231.1 - 3.6e-15 56.3 0.2 4.5e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 Sec8_exocyst PF04048.14 RUS70232.1 - 0.14 12.0 2.2 0.41 10.5 2.2 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain SAC3_GANP PF03399.16 RUS70233.1 - 1.3e-70 238.1 0.3 2e-70 237.5 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family DUF1877 PF08974.10 RUS70234.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) RVT_1 PF00078.27 RUS70235.1 - 8.5e-35 120.3 0.1 1.3e-34 119.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 RUS70235.1 - 0.22 10.8 27.3 0.43 9.8 27.3 1.5 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 RUS70235.1 - 0.26 10.0 23.2 0.36 9.6 23.2 1.2 1 0 0 1 1 1 0 Presenilin CNDH2_C PF16858.5 RUS70235.1 - 2.1 8.2 9.3 3.5 7.4 9.3 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 RUS70235.1 - 2.2 6.2 34.3 3.3 5.7 34.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS70235.1 - 3.1 5.9 20.8 4.5 5.4 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family Agglutinin PF07468.11 RUS70236.1 - 2.9e-06 27.5 1.4 1.6 8.9 0.0 4.4 1 1 1 2 2 2 2 Agglutinin domain SF3b1 PF08920.10 RUS70236.1 - 0.0044 17.5 8.9 3.2 8.3 3.8 3.5 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 Aegerolysin PF06355.13 RUS70236.1 - 0.13 12.4 0.3 16 5.5 0.0 3.4 1 1 4 5 5 5 0 Aegerolysin eIF-3_zeta PF05091.12 RUS70236.1 - 0.45 9.4 1.4 5.4 5.9 0.1 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lectin_C PF00059.21 RUS70237.1 - 1.7e-13 51.2 0.1 3.3e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS70237.1 - 0.0043 17.0 0.2 0.0086 16.0 0.2 1.6 1 0 0 1 1 1 1 PAN domain Lectin_C PF00059.21 RUS70238.1 - 4.1e-14 53.2 0.8 8e-14 52.3 0.8 1.5 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS70238.1 - 0.00023 21.1 0.1 0.00058 19.8 0.1 1.7 1 0 0 1 1 1 1 PAN domain Cu_amine_oxid PF01179.20 RUS70239.1 - 5.4e-99 331.9 8.9 1.8e-97 326.9 8.9 2.3 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 RUS70239.1 - 6e-11 42.6 0.0 2e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain DUF1965 PF09248.10 RUS70239.1 - 8.7e-06 25.4 1.1 1e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 RUS70239.1 - 9.4e-05 22.6 0.0 0.00031 20.9 0.0 1.9 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain VWA PF00092.28 RUS70240.1 - 5.3e-61 205.9 2.4 7.2e-39 133.8 0.9 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS70240.1 - 2.8e-26 92.2 0.7 7.6e-19 68.3 0.2 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 RUS70240.1 - 5.8e-09 36.1 0.2 5.4e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain AhpC-TSA_2 PF13911.6 RUS70240.1 - 0.043 13.9 0.0 4.9 7.3 0.0 2.8 3 0 0 3 3 3 0 AhpC/TSA antioxidant enzyme ShK PF01549.24 RUS70240.1 - 0.066 13.8 1.2 0.15 12.6 1.2 1.6 1 0 0 1 1 1 0 ShK domain-like SDF PF00375.18 RUS70242.1 - 3.2e-44 151.5 17.5 3.6e-44 151.4 17.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Med26 PF08711.11 RUS70243.1 - 3.8e-13 49.2 0.0 9.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LEA_6 PF10714.9 RUS70244.1 - 0.0017 18.4 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 Late embryogenesis abundant protein 18 Exo_endo_phos_2 PF14529.6 RUS70244.1 - 0.0089 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF962 PF06127.11 RUS70244.1 - 0.018 15.1 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Erv26 PF04148.13 RUS70244.1 - 0.077 12.8 0.6 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Transmembrane adaptor Erv26 PRiA4_ORF3 PF07929.11 RUS70244.1 - 0.085 12.6 2.6 6.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Plasmid pRiA4b ORF-3-like protein tRNA-synt_2c PF01411.19 RUS70244.1 - 0.1 11.1 1.4 0.11 11.0 0.4 1.4 2 0 0 2 2 2 0 tRNA synthetases class II (A) SUIM_assoc PF16619.5 RUS70244.1 - 0.35 11.0 17.1 1.3 9.1 2.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2489 PF10675.9 RUS70244.1 - 2 8.4 8.9 8.7 6.3 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) LigB PF02900.18 RUS70245.1 - 4.1e-06 26.1 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PAC2 PF09754.9 RUS70246.1 - 2.8e-26 92.8 0.0 3.3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 PAC2 family YjeF_N PF03853.15 RUS70246.1 - 0.048 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Nop14 PF04147.12 RUS70248.1 - 7.8e-07 27.7 39.4 9.1e-07 27.5 39.4 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS70248.1 - 6.4e-06 24.8 33.1 7.2e-06 24.6 33.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 RUS70248.1 - 0.00039 20.0 60.7 0.0005 19.6 60.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) YL1 PF05764.13 RUS70248.1 - 0.0052 16.9 56.1 0.0075 16.4 56.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Merozoite_SPAM PF07133.11 RUS70248.1 - 0.013 15.5 69.3 0.017 15.2 69.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) NAD_binding_8 PF13450.6 RUS70248.1 - 0.058 13.6 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CCSAP PF15748.5 RUS70248.1 - 0.2 11.8 34.2 0.28 11.3 34.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4604 PF15377.6 RUS70248.1 - 0.3 11.5 50.4 0.57 10.6 50.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Hid1 PF12722.7 RUS70248.1 - 3.9 5.5 24.8 4.7 5.2 24.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FYDLN_acid PF09538.10 RUS70248.1 - 4 8.2 36.9 0.77 10.5 20.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SLC12 PF03522.15 RUS70248.1 - 8 5.4 30.4 9.7 5.1 30.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAD_binding_3 PF01494.19 RUS70249.1 - 4.1e-25 88.8 0.0 4.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RUS70249.1 - 0.011 16.0 0.0 0.039 14.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pou PF00157.17 RUS70251.1 - 1.1e-37 127.8 0.1 2.2e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RUS70251.1 - 2.4e-18 65.7 0.2 2.4e-18 65.7 0.2 2.2 3 0 0 3 3 3 1 Homeodomain HTH_31 PF13560.6 RUS70251.1 - 0.063 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SDF PF00375.18 RUS70252.1 - 5.5e-54 183.7 25.3 9.4e-53 179.6 17.1 2.1 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family DUF525 PF04379.14 RUS70252.1 - 0.0012 19.0 15.3 5.8 7.2 0.2 5.3 1 1 4 5 5 5 3 ApaG domain PGF-CTERM PF18204.1 RUS70252.1 - 0.01 15.8 0.4 11 6.1 0.1 3.4 2 0 0 2 2 2 0 PGF-CTERM motif YolD PF08863.10 RUS70252.1 - 0.49 10.5 3.6 43 4.3 0.2 3.1 1 1 2 3 3 3 0 YolD-like protein Nbas_N PF15492.6 RUS70252.1 - 1.1 8.6 7.7 27 3.9 0.4 3.7 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal MtrF PF09472.10 RUS70253.1 - 0.59 9.6 3.8 19 4.7 0.3 3.8 2 1 3 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) NFACT-C PF11923.8 RUS70253.1 - 2.9 7.9 4.7 66 3.5 1.4 3.7 3 1 0 3 3 3 0 NFACT protein C-terminal domain SDF PF00375.18 RUS70254.1 - 1.4e-13 50.6 24.2 0.0024 17.0 1.6 4.1 3 1 1 4 4 4 4 Sodium:dicarboxylate symporter family DUF1294 PF06961.13 RUS70254.1 - 0.18 12.1 4.8 83 3.5 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1294) RVT_2 PF07727.14 RUS70255.1 - 6.1e-74 248.7 1.1 9.8e-74 248.0 1.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS70255.1 - 4.8e-20 71.9 0.2 1.5e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 RUS70255.1 - 4.3e-18 65.3 1.9 3e-16 59.3 0.5 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 RUS70255.1 - 4.7e-08 32.8 0.3 1.9e-07 30.9 0.2 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 RUS70255.1 - 7.4e-05 22.6 5.4 7.4e-05 22.6 5.4 2.8 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 RUS70255.1 - 0.0031 17.3 0.1 0.0076 16.0 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain DUF3482 PF11981.8 RUS70255.1 - 0.2 11.0 0.2 0.34 10.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CNOT11 PF10155.9 RUS70257.1 - 3.3e-53 179.1 7.7 6.2e-53 178.2 7.7 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Dynein_light PF01221.18 RUS70259.1 - 0.23 11.8 14.1 2.6 8.4 1.2 3.0 1 1 2 3 3 3 0 Dynein light chain type 1 adh_short_C2 PF13561.6 RUS70262.1 - 8.2e-53 179.4 0.3 1e-52 179.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS70262.1 - 4.9e-42 143.6 0.3 6.5e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS70262.1 - 1.5e-07 31.5 0.1 2.7e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS70262.1 - 0.026 14.0 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RUS70262.1 - 0.042 13.7 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cation_efflux PF01545.21 RUS70263.1 - 2.3e-16 60.1 15.9 3.6e-16 59.5 15.9 1.3 1 1 0 1 1 1 1 Cation efflux family DUF4834 PF16118.5 RUS70263.1 - 0.0092 16.9 1.1 0.0092 16.9 1.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) MARVEL PF01284.23 RUS70263.1 - 0.17 11.9 5.0 7.6 6.6 4.7 2.3 1 1 1 2 2 2 0 Membrane-associating domain Zip PF02535.22 RUS70263.1 - 4 6.6 19.5 9.3 5.4 19.2 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter SUR7 PF06687.12 RUS70263.1 - 5.1 6.7 8.1 26 4.3 8.1 2.1 1 1 0 1 1 1 0 SUR7/PalI family HtrL_YibB PF09612.10 RUS70265.1 - 1.2e-36 126.6 0.0 2e-36 125.9 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Potass_KdpF PF09604.10 RUS70265.1 - 7.7 6.6 8.1 17 5.5 8.1 1.6 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) SCO1-SenC PF02630.14 RUS70266.1 - 0.0082 16.1 0.2 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 SCO1/SenC dNK PF01712.19 RUS70267.1 - 4.8e-12 46.2 0.6 1.1e-11 44.9 0.1 1.8 2 0 0 2 2 2 1 Deoxynucleoside kinase DUF1929 PF09118.11 RUS70268.1 - 0.07 13.4 0.3 0.13 12.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) DUF5343 PF17278.2 RUS70270.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5343) SfsA_N PF17746.1 RUS70275.1 - 0.027 14.6 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 SfsA N-terminal OB domain DUF3915 PF13054.6 RUS70275.1 - 0.033 14.2 0.4 0.091 12.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Spc24 PF08286.11 RUS70275.1 - 0.048 13.9 4.4 0.078 13.2 4.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 EMP24_GP25L PF01105.24 RUS70275.1 - 0.089 12.7 1.6 0.14 12.1 1.6 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Hydin_ADK PF17213.3 RUS70275.1 - 0.51 10.6 4.6 6.8 6.9 2.2 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain LMBR1 PF04791.16 RUS70275.1 - 3.5 6.4 3.7 4.8 6.0 3.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_Helicase PF02689.14 RUS70276.1 - 0.00047 18.2 5.7 0.021 12.8 0.5 2.8 3 0 0 3 3 3 2 Helicase Nop14 PF04147.12 RUS70276.1 - 0.043 12.0 3.8 0.076 11.2 3.8 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 RUS70276.1 - 0.56 8.7 20.1 1.1 7.7 20.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4604 PF15377.6 RUS70276.1 - 2.1 8.8 14.7 5.3 7.4 14.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CDC45 PF02724.14 RUS70276.1 - 6.9 4.8 12.4 13 4.0 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribonuc_red_sm PF00268.21 RUS70277.1 - 2.4e-14 53.5 6.5 3.5e-14 52.9 6.5 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Svf1_C PF17187.4 RUS70277.1 - 0.03 14.2 0.4 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain Ribonuc_red_lgC PF02867.15 RUS70281.1 - 3.5e-44 151.2 0.0 1.1e-43 149.6 0.0 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain PARG_cat PF05028.14 RUS70282.1 - 4.7e-54 183.9 0.0 7.3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) NOA36 PF06524.12 RUS70282.1 - 0.11 11.8 5.0 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 NOA36 protein YxiJ PF14176.6 RUS70283.1 - 0.042 14.3 0.1 5 7.6 0.0 2.4 2 0 0 2 2 2 0 YxiJ-like protein Jacalin PF01419.17 RUS70284.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain PARG_cat PF05028.14 RUS70285.1 - 1.9e-36 126.0 0.0 1.9e-36 126.0 0.0 2.1 2 0 0 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) SET PF00856.28 RUS70285.1 - 2.1e-08 34.7 0.1 2.1e-08 34.7 0.1 9.6 8 2 0 8 8 8 1 SET domain OTU PF02338.19 RUS70285.1 - 0.00012 22.6 0.0 0.00076 20.0 0.0 2.5 1 0 0 1 1 1 1 OTU-like cysteine protease Cas_APE2256 PF09651.10 RUS70287.1 - 0.74 9.7 4.3 37 4.2 0.0 3.9 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_APE2256) zf-C3HC4_3 PF13920.6 RUS70289.1 - 1.6e-13 50.3 15.7 1.1e-12 47.6 12.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 RUS70289.1 - 5.5e-12 46.2 0.6 5.5e-12 46.2 0.6 3.3 3 1 1 4 4 4 1 Inhibitor of Apoptosis domain Prok-RING_4 PF14447.6 RUS70289.1 - 2e-06 27.6 11.2 2e-06 27.6 11.2 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS70289.1 - 0.00067 19.9 12.4 0.00067 19.9 12.4 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RUS70289.1 - 0.0097 15.9 12.5 0.0097 15.9 12.5 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C2HC_2 PF13913.6 RUS70289.1 - 0.051 13.5 0.4 0.051 13.5 0.4 4.1 3 1 1 4 4 4 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 RUS70289.1 - 2.2 8.6 11.9 5 7.5 1.8 3.4 3 2 0 3 3 3 0 zinc-ribbon efThoc1 PF11957.8 RUS70297.1 - 8.4e-86 288.6 16.7 8.4e-86 288.6 16.7 1.4 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 RUS70297.1 - 7.6e-10 38.8 0.2 2.4e-09 37.2 0.2 1.9 1 0 0 1 1 1 1 Death domain YvbH_ext PF11724.8 RUS70297.1 - 0.042 14.2 2.7 2.2 8.7 0.1 3.1 2 0 0 2 2 2 0 YvbH-like oligomerisation region TTL PF03133.15 RUS70298.1 - 9.2e-83 277.7 0.9 2.6e-82 276.3 0.4 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS70298.1 - 4.6e-09 35.9 2.1 0.00042 19.7 0.0 3.4 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS70298.1 - 7.6e-05 22.1 0.0 0.069 12.4 0.0 2.7 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RUS70298.1 - 0.00043 20.4 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 RUS70298.1 - 0.0049 16.5 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF4407 PF14362.6 RUS70298.1 - 0.073 12.4 0.5 0.13 11.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 RUS70298.1 - 0.27 11.3 4.0 0.64 10.1 4.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fibrinogen_C PF00147.18 RUS70299.1 - 1.3e-56 191.9 4.8 1.4e-56 191.8 3.8 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain ABC_tran_CTD PF16326.5 RUS70299.1 - 0.00053 20.2 17.1 0.05 13.9 0.6 3.9 2 1 2 4 4 4 3 ABC transporter C-terminal domain Med9 PF07544.13 RUS70299.1 - 0.0018 18.3 5.9 0.083 13.0 0.3 2.6 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 RUS70299.1 - 0.006 17.0 11.3 0.12 12.8 6.2 3.3 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 RUS70299.1 - 0.0076 16.4 9.4 0.036 14.2 9.4 2.0 1 1 0 1 1 1 1 Tropomyosin like Spectrin PF00435.21 RUS70299.1 - 0.02 15.4 3.2 0.051 14.1 0.8 2.3 1 1 1 2 2 2 0 Spectrin repeat Matrilin_ccoil PF10393.9 RUS70299.1 - 0.024 14.5 9.7 6.7 6.7 0.1 4.5 2 1 2 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin HSBP1 PF06825.12 RUS70299.1 - 0.03 14.2 12.7 4 7.4 1.4 3.8 1 1 2 3 3 3 0 Heat shock factor binding protein 1 TRAF_BIRC3_bd PF16673.5 RUS70299.1 - 0.05 13.4 2.8 9 6.2 0.6 3.6 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF3584 PF12128.8 RUS70299.1 - 0.053 11.0 5.9 0.071 10.6 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 RUS70299.1 - 0.06 13.7 14.2 0.061 13.6 2.0 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 RUS70299.1 - 0.081 13.0 13.5 0.99 9.4 6.1 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 RUS70299.1 - 0.092 12.8 7.9 0.14 12.3 7.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 RUS70299.1 - 0.1 11.2 8.3 0.04 12.5 5.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 RUS70299.1 - 0.12 12.7 6.6 1.6 9.1 6.6 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HMMR_N PF15905.5 RUS70299.1 - 0.13 11.8 12.5 0.17 11.3 12.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PLAC9 PF15205.6 RUS70299.1 - 0.25 11.8 2.1 19 5.8 0.1 2.9 1 1 1 2 2 2 0 Placenta-specific protein 9 DUF2730 PF10805.8 RUS70299.1 - 0.25 11.4 8.4 0.46 10.6 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) XhlA PF10779.9 RUS70299.1 - 0.26 11.5 20.2 0.061 13.5 4.6 3.7 2 1 3 5 5 5 0 Haemolysin XhlA Viral_P18 PF04521.13 RUS70299.1 - 0.28 11.0 2.2 6.7 6.5 0.1 2.8 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1664 PF07889.12 RUS70299.1 - 0.33 11.0 10.0 2.8 8.0 5.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RP854 PF17460.2 RUS70299.1 - 0.35 10.6 3.3 0.72 9.6 0.1 2.6 3 1 0 3 3 3 0 Uncharacterized protein RP854 zf-ZPR1 PF03367.13 RUS70299.1 - 0.49 10.2 7.7 8.4 6.2 0.3 2.6 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Prefoldin_2 PF01920.20 RUS70299.1 - 0.57 10.2 13.4 29 4.7 8.6 3.8 1 1 1 2 2 2 0 Prefoldin subunit DUF4927 PF16279.5 RUS70299.1 - 0.67 11.0 5.6 1.1 10.3 2.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4927) RRN3 PF05327.11 RUS70299.1 - 0.74 8.3 7.4 0.93 8.0 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2536 PF10750.9 RUS70299.1 - 0.83 9.6 3.6 18 5.3 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2536) FliD_N PF02465.18 RUS70299.1 - 0.84 10.4 13.6 1.8 9.3 1.0 3.3 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4164 PF13747.6 RUS70299.1 - 0.94 9.8 7.5 2.4 8.5 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DASH_Dad4 PF08650.10 RUS70299.1 - 1.8 8.6 7.7 18 5.4 0.7 3.8 2 1 2 4 4 4 0 DASH complex subunit Dad4 RPW8 PF05659.11 RUS70299.1 - 2.1 8.1 12.3 1.3 8.7 2.8 3.2 1 1 3 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 RUS70299.1 - 2.3 8.2 9.2 4.4 7.3 0.4 2.7 1 1 2 3 3 3 0 Laminin Domain II FlaC_arch PF05377.11 RUS70299.1 - 2.5 8.6 16.1 1.2e+03 -0.0 12.8 3.8 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 RUS70299.1 - 3 8.4 11.3 1.1 9.7 4.7 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 RUS70299.1 - 3.9 7.6 10.5 14 5.8 1.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tnp_22_trimer PF17489.2 RUS70299.1 - 8.6 6.4 12.9 0.97 9.5 1.0 3.5 2 1 2 4 4 3 0 L1 transposable element trimerization domain AMA-1 PF02430.15 RUS70301.1 - 0.069 12.1 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Pkinase PF00069.25 RUS70303.1 - 1.6e-62 211.3 0.0 3e-34 118.6 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70303.1 - 7.7e-24 84.4 0.0 2.6e-22 79.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS70303.1 - 3.8e-08 32.9 1.2 4.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS70303.1 - 0.00039 19.8 1.3 0.012 15.0 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 RUS70303.1 - 0.026 14.1 3.3 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Cornifin PF02389.15 RUS70305.1 - 4.4e-05 23.7 66.2 0.092 12.9 33.4 2.5 1 1 1 2 2 2 2 Cornifin (SPRR) family eIF_4EBP PF05456.11 RUS70306.1 - 7.7e-39 132.2 1.0 8.6e-39 132.0 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Claudin_2 PF13903.6 RUS70307.1 - 9.6e-06 25.5 0.5 2.3e-05 24.2 0.5 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS70307.1 - 0.0032 17.4 2.7 0.017 15.0 2.7 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family zf-H2C2_2 PF13465.6 RUS70308.1 - 7.3e-52 171.6 57.1 3.9e-09 36.5 1.6 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS70308.1 - 5.5e-40 133.6 58.7 3.3e-06 27.3 2.3 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS70308.1 - 9.6e-33 110.0 53.5 0.00018 22.1 1.9 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS70308.1 - 1.1e-24 85.9 58.3 0.00014 21.8 0.4 8.5 8 1 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS70308.1 - 3.4e-17 62.2 31.1 0.002 18.4 0.2 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS70308.1 - 4.4e-17 61.9 40.0 0.0014 19.0 0.7 8.1 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS70308.1 - 2.4e-07 31.0 26.8 0.035 14.4 1.3 5.0 3 1 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding Ta0938 PF11494.8 RUS70308.1 - 8.6e-05 22.8 15.2 1.5 9.2 0.2 5.0 1 1 4 5 5 5 2 Ta0938 Zn-ribbon_8 PF09723.10 RUS70308.1 - 0.00012 22.2 36.5 0.26 11.4 2.1 6.7 4 3 4 8 8 8 4 Zinc ribbon domain zf_UBZ PF18439.1 RUS70308.1 - 0.00015 21.3 26.1 0.79 9.4 0.0 8.1 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 RUS70308.1 - 0.00017 21.3 23.3 0.17 11.6 0.0 7.1 7 0 0 7 7 7 1 zinc-finger C2H2-type ADK_lid PF05191.14 RUS70308.1 - 0.001 19.0 30.8 0.015 15.3 0.7 5.7 4 2 1 5 5 5 2 Adenylate kinase, active site lid HypA PF01155.19 RUS70308.1 - 0.0014 18.7 19.0 0.054 13.5 1.1 4.5 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAGA PF09237.11 RUS70308.1 - 0.0016 18.2 5.3 0.35 10.7 0.0 4.0 2 1 0 4 4 4 1 GAGA factor BolA PF01722.18 RUS70308.1 - 0.0032 17.7 8.4 4.4 7.7 0.2 4.7 2 1 1 3 3 3 1 BolA-like protein zf-C2HC_2 PF13913.6 RUS70308.1 - 0.0032 17.3 31.4 2 8.4 0.0 7.2 7 0 0 7 7 7 2 zinc-finger of a C2HC-type FYVE PF01363.21 RUS70308.1 - 0.0035 17.5 30.5 8.5 6.6 0.1 4.8 1 1 1 3 3 3 0 FYVE zinc finger XPA_N PF01286.18 RUS70308.1 - 0.0052 16.8 31.8 7.9 6.6 0.1 8.1 8 0 0 8 8 8 0 XPA protein N-terminal zf-H2C2_5 PF13909.6 RUS70308.1 - 0.0068 16.1 1.0 0.0068 16.1 1.0 7.9 8 2 0 8 8 6 1 C2H2-type zinc-finger domain zf-FCS PF06467.14 RUS70308.1 - 0.037 14.0 3.1 0.037 14.0 3.1 5.2 7 0 0 7 7 6 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_15 PF17032.5 RUS70308.1 - 0.058 14.1 23.8 3.8 8.3 0.8 4.6 1 1 5 6 6 6 0 zinc-ribbon family zf-BED PF02892.15 RUS70308.1 - 0.06 13.4 36.2 1.7 8.7 0.4 7.3 1 1 5 6 6 6 0 BED zinc finger DUF4428 PF14471.6 RUS70308.1 - 0.083 12.8 14.7 1.1 9.2 0.3 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4428) FYDLN_acid PF09538.10 RUS70308.1 - 0.17 12.6 22.1 0.28 11.9 2.0 6.3 2 2 6 8 8 8 0 Protein of unknown function (FYDLN_acid) Arc_trans_TRASH PF08394.10 RUS70308.1 - 0.2 12.0 20.5 19 5.7 3.5 7.1 6 1 1 7 7 7 0 Archaeal TRASH domain LIM PF00412.22 RUS70308.1 - 0.23 11.7 32.0 12 6.2 3.3 6.5 1 1 6 7 7 7 0 LIM domain zf-MYST PF17772.1 RUS70308.1 - 0.27 10.9 25.6 0.63 9.7 0.1 7.4 4 2 4 8 8 8 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 RUS70308.1 - 0.55 9.9 27.7 2.8 7.7 0.7 6.1 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 RUS70308.1 - 0.86 9.9 20.4 4.9 7.5 1.7 4.4 1 1 6 7 7 7 0 zinc-finger-containing domain WAPL PF07814.13 RUS70309.1 - 1.8e-85 286.9 17.1 2.9e-85 286.3 17.1 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 RUS70309.1 - 0.11 11.6 4.1 0.061 12.5 1.8 1.7 2 0 0 2 2 2 0 Wap1 domain zf-C2H2_2 PF12756.7 RUS70309.1 - 1.5 9.2 4.4 0.44 10.9 0.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SNF PF00209.18 RUS70311.1 - 2.5e-07 29.8 4.6 2.5e-07 29.8 4.6 1.5 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family Thyroglob_assoc PF16597.5 RUS70312.1 - 0.066 13.5 4.9 32 4.9 0.1 4.0 1 1 3 4 4 4 0 Thyroglobulin_1 repeat associated disordered domain HTH_48 PF17906.1 RUS70313.1 - 0.00051 20.1 0.2 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 RUS70313.1 - 0.00064 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain DUF4817 PF16087.5 RUS70313.1 - 0.024 14.4 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) V_ATPase_I PF01496.19 RUS70314.1 - 0.017 13.1 2.0 0.019 12.9 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 RUS70314.1 - 0.03 12.7 0.4 0.035 12.5 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 RUS70314.1 - 0.098 11.7 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 CLN3 protein eIF3_subunit PF08597.10 RUS70314.1 - 0.75 9.7 25.9 0.95 9.3 25.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 RUS70314.1 - 9 4.4 24.1 10 4.3 24.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS70314.1 - 9.6 5.9 17.6 11 5.7 17.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roc PF08477.13 RUS70315.1 - 4.8e-14 52.6 0.0 5.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS70315.1 - 4.3e-10 39.4 0.0 4.8e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 RUS70315.1 - 1.1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS70315.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RUS70315.1 - 0.0097 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 RUS70315.1 - 0.011 15.8 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 RUS70315.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RUS70315.1 - 0.057 14.0 0.0 0.064 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS70315.1 - 0.093 13.0 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 RUS70315.1 - 0.099 11.8 0.0 0.29 10.2 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit Adaptin_N PF01602.20 RUS70316.1 - 1.4e-158 528.7 17.9 1.8e-158 528.4 17.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RUS70316.1 - 2.3e-67 226.1 10.0 3.2e-64 215.9 2.8 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 RUS70316.1 - 3e-32 111.0 0.2 1.3e-31 109.0 0.2 2.2 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 RUS70316.1 - 1.6e-18 66.9 6.4 2.3e-07 31.1 0.2 5.8 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 RUS70316.1 - 6.7e-12 44.6 8.2 0.008 16.4 0.1 6.7 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 RUS70316.1 - 1.5e-11 44.6 1.8 1.5e-11 44.6 1.8 2.2 3 0 0 3 3 2 1 Adaptin C-terminal domain Arm PF00514.23 RUS70316.1 - 5.6e-07 29.4 3.8 0.015 15.3 0.1 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 RUS70316.1 - 5.9e-07 29.0 4.8 1.8e-05 24.1 0.2 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 RUS70316.1 - 7e-05 22.5 1.9 0.47 10.0 0.1 3.9 2 2 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 RUS70316.1 - 0.00082 19.8 3.4 12 6.6 0.0 6.1 6 1 2 8 8 8 0 HEAT-like repeat RTP1_C1 PF10363.9 RUS70316.1 - 0.0025 18.0 6.4 3.2 8.0 0.0 5.1 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptin_C PF02296.16 RUS70316.1 - 0.0032 17.7 0.7 0.014 15.6 0.1 2.4 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain UNC45-central PF11701.8 RUS70316.1 - 0.0036 17.3 0.9 0.13 12.2 0.1 3.0 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 RUS70316.1 - 0.0098 15.8 4.1 0.014 15.3 0.7 3.0 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Atx10homo_assoc PF09759.9 RUS70316.1 - 0.013 15.5 2.9 7.5 6.7 0.1 4.5 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain TIP120 PF08623.10 RUS70316.1 - 0.024 14.4 10.2 3.3 7.5 0.1 4.8 3 1 2 5 5 5 0 TATA-binding protein interacting (TIP20) DUF5578 PF17741.1 RUS70316.1 - 0.058 12.8 4.6 0.71 9.2 0.5 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5578) RasGEF_N_2 PF14663.6 RUS70316.1 - 1.2 9.6 5.1 18 5.8 0.1 4.5 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CUE PF02845.16 RUS70317.1 - 4.6e-10 39.0 0.1 1.1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain NDT80_PhoG PF05224.12 RUS70317.1 - 0.017 15.4 0.3 0.032 14.4 0.3 1.4 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family ThiJ_like PF17124.5 RUS70318.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 RUS70319.1 - 2.1e-05 24.4 0.0 0.0012 18.7 0.0 2.3 1 1 1 2 2 2 2 DJ-1/PfpI family SWIM PF04434.17 RUS70320.1 - 0.00041 20.0 2.8 0.00087 18.9 2.8 1.5 1 0 0 1 1 1 1 SWIM zinc finger Presenilin PF01080.17 RUS70320.1 - 0.08 11.7 2.6 0.14 10.9 2.6 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_S11 PF00411.19 RUS70321.1 - 1.1e-46 157.7 1.1 1.5e-46 157.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 RUS70321.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Methyltransf_16 PF10294.9 RUS70323.1 - 0.021 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF1556 PF07590.11 RUS70324.1 - 0.069 13.5 1.9 1.1 9.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) 2OG-FeII_Oxy_2 PF13532.6 RUS70324.1 - 0.081 13.1 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Somatomedin_B PF01033.17 RUS70325.1 - 6.3e-09 36.1 10.6 2e-08 34.5 10.6 1.9 1 0 0 1 1 1 1 Somatomedin B domain PMP22_Claudin PF00822.20 RUS70325.1 - 0.01 15.7 2.5 0.025 14.5 2.5 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family p450 PF00067.22 RUS70326.1 - 2.2e-80 270.7 0.6 9.5e-80 268.6 0.6 1.7 1 1 0 1 1 1 1 Cytochrome P450 CUB PF00431.20 RUS70327.1 - 0.00048 20.4 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 RUS70327.1 - 0.0028 17.8 1.3 0.0098 16.1 1.3 2.0 1 0 0 1 1 1 1 Thrombospondin type 1 domain DUF229 PF02995.17 RUS70328.1 - 7.2e-23 81.0 0.0 1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Bact_lectin PF18483.1 RUS70328.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial lectin Metalloenzyme PF01676.18 RUS70328.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily zf-C2H2 PF00096.26 RUS70329.1 - 9.1e-25 85.7 86.9 0.00035 20.9 2.3 12.2 12 0 0 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS70329.1 - 2.7e-21 74.4 87.5 0.0033 18.1 3.6 11.9 12 0 0 12 12 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS70329.1 - 5.3e-13 48.7 11.6 1.6e-07 31.4 0.7 10.2 11 0 0 11 11 10 3 Zinc-finger double domain zf-met PF12874.7 RUS70329.1 - 1.2e-12 47.7 58.3 0.019 15.4 0.3 9.9 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS70329.1 - 1.9e-10 40.7 44.9 0.14 12.5 2.4 10.7 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS70329.1 - 1.5e-07 31.0 2.5 1.5e-07 31.0 2.5 7.0 8 0 0 8 8 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS70329.1 - 0.01 15.8 0.4 0.01 15.8 0.4 10.7 12 0 0 12 12 11 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS70329.1 - 0.051 13.2 0.1 0.051 13.2 0.1 6.6 6 1 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 RUS70329.1 - 0.33 11.3 4.8 28 5.1 0.3 4.2 3 2 0 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.7 RUS70329.1 - 0.33 11.3 48.5 1.3 9.4 0.5 8.5 4 2 2 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 RUS70329.1 - 0.74 9.6 57.5 0.14 11.9 0.8 8.6 8 0 0 8 8 8 0 zinc-finger C2H2-type Terminase_GpA PF05876.12 RUS70329.1 - 2 6.9 7.8 0.64 8.5 0.8 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Na_H_Exchanger PF00999.21 RUS70330.1 - 4.4e-13 48.8 12.6 6e-13 48.3 12.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sulfotransfer_2 PF03567.14 RUS70331.1 - 1.6e-22 80.7 0.2 2.1e-22 80.3 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase family PID_2 PF14719.6 RUS70332.1 - 1.3e-60 204.4 0.2 1.8e-60 203.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 RUS70332.1 - 0.013 15.6 0.1 0.069 13.2 0.1 2.0 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) ORC6 PF05460.13 RUS70332.1 - 0.23 10.7 3.1 0.49 9.6 2.9 1.5 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DDE_Tnp_1_7 PF13843.6 RUS70333.1 - 7.1e-39 134.1 0.0 1e-38 133.6 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Transposase_1 PF01359.18 RUS70334.1 - 2.8e-07 30.2 0.1 5.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS70334.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease fn3 PF00041.21 RUS70335.1 - 1.1e-06 28.8 4.1 0.00014 22.1 0.0 3.3 4 0 0 4 4 4 2 Fibronectin type III domain Trypsin_2 PF13365.6 RUS70338.1 - 2.5e-11 44.7 0.0 4.5e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RUS70338.1 - 0.0022 17.9 0.2 0.0082 16.0 0.2 1.8 1 1 0 1 1 1 1 Trypsin TPR_12 PF13424.6 RUS70339.1 - 1.2e-82 272.3 19.8 1.2e-19 70.3 0.0 6.2 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 RUS70339.1 - 2.8e-65 214.6 16.0 1.2e-12 47.2 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 RUS70339.1 - 4e-31 105.5 16.7 2.7e-05 23.8 0.1 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 RUS70339.1 - 6.6e-31 104.1 13.9 5.6e-05 22.9 0.0 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70339.1 - 2.5e-23 80.3 18.4 3.2e-05 23.8 0.1 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS70339.1 - 1.2e-20 74.2 2.5 1.3e-07 31.3 0.9 3.1 2 1 1 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 RUS70339.1 - 4.4e-20 70.1 25.3 0.00058 19.8 0.1 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS70339.1 - 1.1e-17 64.3 8.0 2.3e-06 28.1 0.1 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS70339.1 - 3e-11 43.2 11.1 0.007 17.1 0.0 7.0 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS70339.1 - 1e-09 38.1 5.8 3.3 8.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat SNAP PF14938.6 RUS70339.1 - 1.6e-07 31.1 0.8 4.9e-07 29.5 0.3 1.9 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 RUS70339.1 - 3.1e-07 30.8 10.6 0.00087 19.8 0.0 5.7 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 RUS70339.1 - 7.9e-05 22.9 1.2 2.9 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS70339.1 - 0.00066 19.9 4.3 0.096 12.9 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 RUS70339.1 - 0.0018 18.2 13.3 1.5 8.9 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 RUS70339.1 - 0.0019 17.6 6.3 3.8 7.0 0.2 6.0 7 0 0 7 7 7 1 SHNi-TPR TPR_11 PF13414.6 RUS70339.1 - 0.0038 16.9 17.0 0.22 11.3 0.1 6.6 6 2 1 7 7 7 2 TPR repeat MIT PF04212.18 RUS70339.1 - 0.053 13.6 11.3 11 6.2 2.0 5.3 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 RUS70339.1 - 0.1 12.3 1.2 6.6 6.4 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 RUS70339.1 - 0.39 11.5 15.7 4.6 8.1 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 RUS70340.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS70340.1 - 0.048 13.5 0.2 0.7 9.8 0.2 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase FAM83 PF07894.12 RUS70341.1 - 4.3 6.8 12.6 6.3 6.3 12.6 1.2 1 0 0 1 1 1 0 FAM83 A-H PAT1 PF09770.9 RUS70341.1 - 9.2 4.4 30.0 11 4.2 30.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_6 PF13516.6 RUS70343.1 - 8.1e-25 84.7 13.6 0.0039 17.1 0.0 12.1 12 0 0 12 12 12 8 Leucine Rich repeat F-box-like PF12937.7 RUS70343.1 - 6.2e-15 54.8 2.1 6.2e-15 54.8 2.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 RUS70343.1 - 4.2e-13 49.2 0.1 3.1 8.3 0.0 8.4 4 3 5 9 9 9 5 Leucine Rich repeats (2 copies) F-box PF00646.33 RUS70343.1 - 1.6e-09 37.4 0.9 1.6e-09 37.4 0.9 2.3 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 RUS70343.1 - 1.3e-05 25.1 22.9 1.2 10.0 0.0 11.1 13 1 0 13 13 13 2 Leucine Rich Repeat SAM_Ste50p PF09235.10 RUS70343.1 - 0.56 10.5 2.0 38 4.6 0.0 4.0 4 1 1 5 5 5 0 Ste50p, sterile alpha motif HSP70 PF00012.20 RUS70344.1 - 2.4e-263 874.8 11.1 2.7e-263 874.6 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS70344.1 - 3e-19 69.0 0.5 1.8e-17 63.1 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 RUS70344.1 - 0.0012 19.3 3.1 1.5 9.3 0.1 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RUS70344.1 - 0.0034 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1464 PF07318.12 RUS70344.1 - 0.0044 16.2 0.0 0.0095 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) BcrAD_BadFG PF01869.20 RUS70344.1 - 0.016 14.7 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 RUS70344.1 - 0.04 12.9 0.2 0.32 10.0 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 RUS70344.1 - 0.066 12.5 1.7 0.16 11.2 0.4 2.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HATPase_c_3 PF13589.6 RUS70345.1 - 0.00029 20.7 0.1 0.00047 20.0 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS70345.1 - 0.0099 16.4 0.3 0.022 15.3 0.3 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Parvo_coat PF00740.18 RUS70345.1 - 0.02 13.6 1.5 2 7.0 0.1 2.0 2 0 0 2 2 2 0 Parvovirus coat protein VP2 Sulfotransfer_1 PF00685.27 RUS70346.1 - 3.6e-55 187.3 4.6 6.6e-54 183.2 4.6 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS70346.1 - 2.3e-06 28.1 0.0 4e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family DUF730 PF05325.11 RUS70346.1 - 0.066 13.2 0.8 0.12 12.4 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF730) Sulfotransfer_1 PF00685.27 RUS70347.1 - 8.5e-15 54.9 0.2 1.4e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase domain zf-TRAF PF02176.18 RUS70348.1 - 1e-16 61.3 19.0 5.4e-16 59.0 6.1 2.7 2 1 1 3 3 3 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 RUS70348.1 - 0.033 14.7 10.5 0.12 12.9 8.1 2.3 1 1 1 2 2 2 0 TRAF-like zinc-finger MATH PF00917.26 RUS70348.1 - 0.092 12.9 0.0 0.58 10.3 0.0 2.3 2 1 0 2 2 2 0 MATH domain Toxin_GhoT_OrtT PF10753.9 RUS70348.1 - 0.3 11.3 1.1 0.52 10.6 0.4 1.8 2 0 0 2 2 2 0 Toxin GhoT_OrtT C_tripleX PF02363.19 RUS70349.1 - 7.4 7.1 24.6 3.1e+02 2.0 8.3 4.3 2 2 0 2 2 2 0 Cysteine rich repeat Smoothelin PF12510.8 RUS70350.1 - 8.4e-17 60.9 3.3 3.1e-09 36.7 1.0 2.3 2 0 0 2 2 2 2 Smoothelin cytoskeleton protein Peptidase_M1_N PF17900.1 RUS70352.1 - 1.4e-41 142.7 0.2 1.7e-41 142.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ABC_export PF16962.5 RUS70353.1 - 0.095 11.1 0.1 0.1 11.0 0.1 1.0 1 0 0 1 1 1 0 Putative ABC exporter F_actin_bind PF08919.10 RUS70353.1 - 0.15 12.2 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 F-actin binding Aminotran_1_2 PF00155.21 RUS70354.1 - 1.5e-72 244.8 0.0 1.8e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 RUS70354.1 - 2.7e-11 44.0 3.3 7.1e-11 42.6 3.3 1.8 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.20 RUS70354.1 - 2.4e-06 26.3 0.0 4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RUS70354.1 - 0.00014 20.9 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RUS70354.1 - 0.00041 19.7 0.0 0.00092 18.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Fibrinogen_aC PF12160.8 RUS70354.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain TEX15 PF15326.6 RUS70354.1 - 0.16 11.7 0.5 0.27 10.9 0.5 1.3 1 0 0 1 1 1 0 Testis expressed sequence 15 7tm_1 PF00001.21 RUS70355.1 - 5.4e-16 58.7 13.0 9e-16 58.0 13.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70355.1 - 0.0014 18.3 10.2 0.0014 18.3 10.2 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS70355.1 - 0.002 17.5 7.8 0.0037 16.7 7.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Quaking_NLS PF16551.5 RUS70355.1 - 0.31 10.7 1.6 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Putative nuclear localisation signal of quaking 7tm_4 PF13853.6 RUS70355.1 - 1.1 8.9 12.8 0.036 13.8 5.8 2.0 2 1 0 2 2 2 0 Olfactory receptor WD40 PF00400.32 RUS70356.1 - 5.6e-23 80.8 0.1 2.3e-05 25.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS70356.1 - 6.8e-13 48.7 0.0 0.0088 16.3 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RUS70356.1 - 0.03 14.3 0.1 0.21 11.5 0.0 2.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 RUS70356.1 - 0.062 11.6 0.0 4.4 5.5 0.0 2.7 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Abhydrolase_1 PF00561.20 RUS70357.1 - 1.4e-15 57.7 0.3 9.1e-14 51.7 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS70357.1 - 9.2e-14 52.6 0.0 1.1e-13 52.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS70357.1 - 5.4e-10 38.9 0.0 1.5e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 RUS70357.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 RUS70357.1 - 0.048 13.8 0.5 0.2 11.7 0.5 1.9 1 1 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 RUS70357.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 RUS70357.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2048 PF09752.9 RUS70357.1 - 0.18 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Hemopexin PF00045.19 RUS70359.1 - 1.5e-38 130.5 23.8 2e-13 50.0 2.7 4.5 4 0 0 4 4 4 4 Hemopexin Peptidase_M10 PF00413.24 RUS70359.1 - 0.0025 17.7 0.1 0.0041 17.0 0.1 1.4 1 0 0 1 1 1 1 Matrixin Pkinase PF00069.25 RUS70361.1 - 8.7e-78 261.3 0.0 1.1e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70361.1 - 7e-39 133.7 0.1 7e-38 130.4 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS70361.1 - 4.9e-07 29.0 0.1 1.1e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RUS70361.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 RUS70361.1 - 0.011 15.1 0.0 0.042 13.2 0.0 1.6 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 RUS70361.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sep15_SelM PF08806.11 RUS70361.1 - 0.083 13.1 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 Sep15/SelM redox domain SAC3_GANP PF03399.16 RUS70362.1 - 6.5e-20 71.7 1.5 9.7e-20 71.1 1.5 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 RUS70362.1 - 1.2e-05 25.3 0.7 2.1e-05 24.5 0.7 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Neur_chan_LBD PF02931.23 RUS70363.1 - 3.1e-27 95.5 0.4 3.1e-27 95.5 0.4 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Tetraspanin PF00335.20 RUS70363.1 - 0.00098 18.9 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Tetraspanin family Neur_chan_memb PF02932.16 RUS70363.1 - 0.0016 18.5 10.0 0.0016 18.5 10.0 2.6 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 RUS70363.1 - 0.022 12.7 0.1 0.033 12.1 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DJ-1_PfpI PF01965.24 RUS70363.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family CIA30 PF08547.12 RUS70365.1 - 1.1e-38 132.7 0.0 1.5e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 RUS70365.1 - 0.015 15.1 0.0 0.038 13.9 0.0 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) CDP-OH_P_transf PF01066.21 RUS70367.1 - 4.7e-13 49.7 1.2 4.7e-13 49.7 1.2 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CarS-like PF01864.17 RUS70367.1 - 0.15 12.0 0.7 0.27 11.2 0.7 1.3 1 0 0 1 1 1 0 CDP-archaeol synthase Acetyltransf_1 PF00583.25 RUS70368.1 - 0.0021 18.3 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DnaJ_CXXCXGXG PF00684.19 RUS70369.1 - 1.2e-05 25.6 14.8 0.03 14.7 13.8 3.2 2 1 1 3 3 3 2 DnaJ central domain Enterotoxin_HS1 PF08090.11 RUS70369.1 - 0.16 11.9 36.7 0.75 9.8 1.2 6.3 6 0 0 6 6 6 0 Heat stable E.coli enterotoxin 1 Sulfotransfer_3 PF13469.6 RUS70370.1 - 2.6e-33 116.2 0.0 4.8e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS70370.1 - 4.7e-08 32.8 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Mpp10 PF04006.12 RUS70372.1 - 4.6 5.6 48.8 5.7 5.2 48.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Transthyretin PF00576.21 RUS70373.1 - 0.039 14.6 0.2 0.14 12.9 0.0 1.8 1 1 1 2 2 2 0 HIUase/Transthyretin family Pkinase_Tyr PF07714.17 RUS70374.1 - 1.3e-85 286.8 0.0 1.5e-83 280.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS70374.1 - 2.4e-39 135.3 0.0 5.1e-37 127.7 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Kringle PF00051.18 RUS70374.1 - 1.1e-22 80.1 3.7 3e-22 78.7 3.7 1.8 1 0 0 1 1 1 1 Kringle domain Fz PF01392.22 RUS70374.1 - 8.6e-06 26.3 0.0 5.9e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Fz domain TMEM154 PF15102.6 RUS70374.1 - 0.00025 21.0 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 RUS70374.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FTA2 PF13095.6 RUS70374.1 - 0.12 12.0 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Syntaxin PF00804.25 RUS70375.1 - 0.019 14.6 1.0 0.041 13.5 1.0 1.5 1 0 0 1 1 1 0 Syntaxin NPR1_interact PF15699.5 RUS70375.1 - 0.065 13.9 0.2 2.4 8.8 0.2 2.2 1 1 0 1 1 1 0 NPR1 interacting DUF3446 PF11928.8 RUS70375.1 - 0.17 12.2 0.2 0.66 10.3 0.2 1.8 1 1 0 1 1 1 0 Early growth response N-terminal domain Hexokinase_2 PF03727.16 RUS70376.1 - 1.7e-75 253.6 0.0 2.4e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RUS70376.1 - 7e-71 238.2 0.0 1.1e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase 7tm_1 PF00001.21 RUS70377.1 - 5.8e-05 22.6 14.7 8.7e-05 22.0 14.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70377.1 - 0.0025 17.5 13.1 0.0025 17.5 13.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS70377.1 - 0.026 13.8 19.7 0.092 12.0 19.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw GTP_EFTU PF00009.27 RUS70378.1 - 1.1e-63 214.3 0.1 1.6e-63 213.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RUS70378.1 - 2.2e-33 114.6 0.0 7.7e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 RUS70378.1 - 2.1e-20 72.5 0.0 5.1e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 RUS70378.1 - 1.8e-12 47.2 0.0 4.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 RUS70378.1 - 9.6e-12 45.1 0.0 2.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RUS70378.1 - 1.5e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase U62_UL91 PF17442.2 RUS70378.1 - 0.061 13.3 0.0 8.1 6.5 0.0 2.8 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins RF3_C PF16658.5 RUS70378.1 - 0.074 12.9 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain CBM_14 PF01607.24 RUS70381.1 - 3.1e-10 40.1 8.5 7.4e-10 38.8 8.5 1.7 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain nlz1 PF12402.8 RUS70381.1 - 0.12 12.8 0.2 0.29 11.6 0.2 1.6 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 zf-C3HC4_4 PF15227.6 RUS70382.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Wzy_C PF04932.15 RUS70383.1 - 0.046 13.3 1.3 0.069 12.8 1.3 1.3 1 0 0 1 1 1 0 O-Antigen ligase Pex24p PF06398.11 RUS70383.1 - 0.17 10.9 0.7 0.21 10.5 0.7 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DEAD PF00270.29 RUS70384.1 - 1.6e-20 73.6 0.0 4.5e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS70384.1 - 1.5e-18 67.1 0.7 7.7e-17 61.6 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS70384.1 - 3.7e-18 66.1 0.1 1e-16 61.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 RUS70384.1 - 1.6e-14 54.1 0.1 4.5e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 RUS70384.1 - 4e-07 30.1 0.6 4e-07 30.1 0.6 2.4 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain AAA_22 PF13401.6 RUS70384.1 - 0.0048 17.2 0.1 0.031 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS70384.1 - 0.0078 16.0 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 RUS70384.1 - 0.0091 16.3 0.4 0.041 14.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain HECT_2 PF09814.9 RUS70384.1 - 0.06 12.2 0.3 0.098 11.5 0.3 1.3 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding UvrD-helicase PF00580.21 RUS70384.1 - 0.15 11.6 1.3 0.56 9.7 0.0 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Ion_trans PF00520.31 RUS70385.1 - 3.2e-37 128.1 14.7 5e-37 127.4 14.7 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS70385.1 - 1.4e-26 92.7 0.0 3.7e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS70385.1 - 2.3e-09 37.1 11.5 2.3e-09 37.1 11.5 2.1 2 0 0 2 2 2 1 Ion channel zf-4CXXC_R1 PF10497.9 RUS70388.1 - 1.5e-37 127.8 9.4 2.4e-37 127.2 9.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 RsbU_N PF08673.10 RUS70388.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain zf-FCS PF06467.14 RUS70388.1 - 1.1 9.2 13.0 0.46 10.5 4.7 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif CEBP_ZZ PF16366.5 RUS70388.1 - 9.9 6.5 12.9 0.053 13.8 2.7 2.2 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Morc6_S5 PF17942.1 RUS70389.1 - 1.5e-35 122.2 0.0 2.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 RUS70389.1 - 5.6e-15 55.4 0.0 8.8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS70389.1 - 0.055 14.0 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tmemb_cc2 PF10267.9 RUS70390.1 - 0.17 11.0 4.8 0.23 10.6 4.8 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2755 PF10954.8 RUS70391.1 - 0.019 14.9 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) CRAL_TRIO_2 PF13716.6 RUS70391.1 - 0.032 14.4 0.7 0.033 14.3 0.7 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Glyco_transf_22 PF03901.17 RUS70394.1 - 8.7e-76 255.8 23.4 1.1e-75 255.5 23.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 RUS70394.1 - 0.0012 19.1 10.8 0.0012 19.1 10.8 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CAP PF00188.26 RUS70395.1 - 4.8e-20 72.7 0.6 5.9e-20 72.4 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ASPRs PF17641.2 RUS70395.1 - 0.022 15.0 0.3 0.37 11.1 0.3 2.2 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related 7tm_1 PF00001.21 RUS70396.1 - 1.1e-14 54.4 2.7 1.4e-14 54.1 2.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4059 PF13268.6 RUS70396.1 - 2 8.9 5.3 0.63 10.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) RVT_1 PF00078.27 RUS70397.1 - 5.8e-19 68.5 0.0 7.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RUS70398.1 - 1.4e-19 69.6 0.1 2.9e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RUS70398.1 - 0.00015 21.7 2.9 0.00023 21.1 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 RUS70398.1 - 0.0005 19.7 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 RUS70398.1 - 0.0018 18.2 0.9 0.0034 17.3 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle DNA_topoisoIV PF00521.20 RUS70398.1 - 0.0027 16.7 0.1 0.0034 16.3 0.1 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Pox_Ag35 PF03286.14 RUS70398.1 - 0.014 15.2 2.7 0.023 14.5 2.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RRM_8 PF11835.8 RUS70398.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain RNA_bind PF08675.11 RUS70398.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain RRM_7 PF16367.5 RUS70398.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 RUS70398.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 1 0 1 1 1 0 Limkain b1 FAM176 PF14851.6 RUS70398.1 - 0.16 11.6 2.2 0.27 10.9 2.2 1.4 1 0 0 1 1 1 0 FAM176 family FCP1_C PF09309.10 RUS70398.1 - 1.2 9.0 10.8 0.82 9.5 7.1 2.0 1 1 1 2 2 2 0 FCP1, C-terminal ANAPC9 PF12856.7 RUS70400.1 - 0.012 15.7 0.3 0.022 14.9 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 VHS PF00790.19 RUS70407.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 VHS domain ALG3 PF05208.13 RUS70408.1 - 2.4e-112 375.9 18.3 3e-112 375.6 18.3 1.0 1 0 0 1 1 1 1 ALG3 protein Adaptin_binding PF10199.9 RUS70411.1 - 0.15 12.6 31.6 0.11 13.1 7.2 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Tim54 PF11711.8 RUS70411.1 - 0.16 10.7 38.8 0.047 12.5 12.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 RUS70411.1 - 0.55 8.4 51.0 0.062 11.5 22.6 2.0 2 0 0 2 2 2 0 Nop14-like family Caldesmon PF02029.15 RUS70411.1 - 0.76 8.5 57.1 0.26 10.0 22.9 2.0 2 0 0 2 2 2 0 Caldesmon DUF4471 PF14740.6 RUS70411.1 - 1.5 8.0 19.6 1.6 7.8 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) MDM1 PF15501.6 RUS70411.1 - 1.9 7.5 47.3 1.3 8.0 19.7 2.0 2 0 0 2 2 2 0 Nuclear protein MDM1 RR_TM4-6 PF06459.12 RUS70411.1 - 3.5 7.4 60.5 0.041 13.7 21.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 RUS70411.1 - 3.6 7.7 48.6 0.16 12.1 18.1 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4746 PF15928.5 RUS70411.1 - 3.6 6.9 47.7 0.68 9.3 18.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Pex14_N PF04695.13 RUS70411.1 - 3.7 8.2 16.2 0.29 11.8 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.9 RUS70411.1 - 3.9 7.6 52.4 0.033 14.3 18.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 RUS70411.1 - 6.3 6.1 62.3 0.048 13.1 23.4 2.0 2 0 0 2 2 2 0 SDA1 DUF913 PF06025.12 RUS70411.1 - 7.4 5.4 26.8 0.95 8.4 8.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Mastoparan PF08249.11 RUS70412.1 - 0.024 15.3 3.0 92 4.2 0.0 4.2 5 0 0 5 5 5 0 Mastoparan protein DUF2457 PF10446.9 RUS70412.1 - 0.49 9.5 9.3 0.66 9.0 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 RUS70412.1 - 0.53 10.7 9.9 0.83 10.1 9.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RUS70412.1 - 1.2 8.4 8.5 1.6 8.0 8.5 1.1 1 0 0 1 1 1 0 NOA36 protein RNase_H2-Ydr279 PF09468.10 RUS70413.1 - 8.3e-11 42.3 0.7 1.9e-10 41.2 0.7 1.6 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain TCP PF03634.13 RUS70413.1 - 0.011 16.3 3.6 0.016 15.8 3.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor TMEM126 PF07114.11 RUS70414.1 - 3.2e-21 75.5 0.7 3.7e-21 75.3 0.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 126 Spot_14 PF07084.12 RUS70415.1 - 2.6e-31 108.8 0.1 3.3e-31 108.5 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 S-methyl_trans PF02574.16 RUS70416.1 - 4e-65 220.3 0.0 4.5e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ank_4 PF13637.6 RUS70417.1 - 9.7e-36 121.7 0.8 7.6e-13 48.7 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS70417.1 - 5.1e-26 89.9 2.0 1.3e-08 34.9 0.3 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RUS70417.1 - 3.7e-24 85.1 0.3 6.7e-15 55.4 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS70417.1 - 7.2e-23 80.4 0.5 7.8e-11 42.0 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS70417.1 - 1.8e-18 64.7 0.0 5e-05 23.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat HPS3_N PF14761.6 RUS70417.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 FA_hydroxylase PF04116.13 RUS70420.1 - 3.3e-20 72.8 20.3 3.3e-20 72.8 20.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sulfotransfer_1 PF00685.27 RUS70421.1 - 1.1e-73 248.0 0.8 2e-73 247.2 0.8 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS70421.1 - 2.5e-09 37.8 0.0 8e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family Lectin_C PF00059.21 RUS70422.1 - 1.7e-12 48.0 0.2 2.8e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS70424.1 - 5.1e-09 36.8 0.4 1e-08 35.9 0.4 1.5 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS70425.1 - 6.9e-14 52.5 0.4 2.3e-13 50.8 0.4 2.0 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS70426.1 - 3.6e-10 40.5 0.3 1.5e-09 38.6 0.1 2.2 2 0 0 2 2 2 1 Lectin C-type domain Laminin_EGF PF00053.24 RUS70427.1 - 0.001 19.1 167.2 0.3 11.2 9.7 12.0 1 1 11 12 12 12 7 Laminin EGF domain COesterase PF00135.28 RUS70428.1 - 7.6e-60 203.2 0.0 1.4e-50 172.6 0.1 2.2 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS70428.1 - 1.7e-07 31.3 0.1 2.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS70428.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS70428.1 - 5.1 7.6 11.1 14 6.2 11.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family RNase_H PF00075.24 RUS70429.1 - 2.9e-05 24.3 0.0 6.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS70429.1 - 0.0017 19.0 0.3 0.0033 18.1 0.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Surp PF01805.20 RUS70429.1 - 0.033 14.2 0.1 0.089 12.8 0.1 1.8 2 0 0 2 2 2 0 Surp module PvlArgDC PF01862.16 RUS70429.1 - 0.084 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) XK-related PF09815.9 RUS70430.1 - 1.8e-48 165.4 31.4 2.5e-48 164.9 31.4 1.1 1 0 0 1 1 1 1 XK-related protein RNA_pol_Rpb5_N PF03871.14 RUS70431.1 - 1.3e-34 118.6 0.0 2.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 RUS70431.1 - 3.1e-34 116.6 0.1 6e-34 115.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain FumaraseC_C PF10415.9 RUS70431.1 - 0.055 13.9 0.2 0.78 10.2 0.0 2.3 2 0 0 2 2 2 0 Fumarase C C-terminus Mrr_cat PF04471.12 RUS70431.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Restriction endonuclease XK-related PF09815.9 RUS70433.1 - 5.4e-87 292.0 25.6 5.4e-87 292.0 25.6 1.8 2 0 0 2 2 2 1 XK-related protein DUF4231 PF14015.6 RUS70433.1 - 0.046 14.2 1.5 6.4 7.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) WXG100 PF06013.12 RUS70434.1 - 1.4 9.2 5.7 0.67 10.2 2.3 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Methyltransf_23 PF13489.6 RUS70435.1 - 2.9e-19 69.5 0.0 5e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS70435.1 - 3.1e-19 69.4 0.0 6.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS70435.1 - 5.9e-16 59.0 0.1 1.3e-15 57.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS70435.1 - 5.8e-14 52.6 0.1 1.6e-13 51.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS70435.1 - 8e-12 45.2 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RUS70435.1 - 3.7e-08 33.0 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RUS70435.1 - 1.2e-06 28.2 0.4 2.2e-06 27.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 RUS70435.1 - 9.5e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 RUS70435.1 - 3.8e-05 23.4 0.1 6.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) ADH_zinc_N PF00107.26 RUS70435.1 - 0.00051 20.0 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GidB PF02527.15 RUS70435.1 - 0.001 18.4 0.1 0.0041 16.5 0.1 1.9 2 1 0 2 2 2 1 rRNA small subunit methyltransferase G MTS PF05175.14 RUS70435.1 - 0.0014 18.2 0.1 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 RUS70435.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 RUS70435.1 - 0.021 14.8 0.4 0.048 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pox_MCEL PF03291.16 RUS70435.1 - 0.23 10.5 2.2 0.9 8.6 0.1 2.4 2 1 0 2 2 2 0 mRNA capping enzyme Peptidase_M16 PF00675.20 RUS70436.1 - 6.8e-33 113.7 0.0 1.1e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RUS70436.1 - 4.2e-31 108.4 0.0 7.1e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2695 PF10905.8 RUS70436.1 - 0.033 14.4 0.1 0.099 12.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) TFIID-31kDa PF02291.15 RUS70436.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_5 PF07728.14 RUS70436.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Proteasome PF00227.26 RUS70437.1 - 4.2e-52 176.4 0.0 5.3e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MutS_I PF01624.20 RUS70438.1 - 8e-17 61.5 0.1 8.7e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 MutS domain I N-glycanase_C PF09113.10 RUS70440.1 - 0.044 13.6 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal DUF4695 PF15766.5 RUS70441.1 - 2.5e-08 34.1 0.3 8.9e-08 32.3 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4695) Kinesin PF00225.23 RUS70443.1 - 8.1e-84 281.4 0.2 9e-84 281.2 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS70443.1 - 2.9e-33 114.9 0.1 4.7e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding Dynamin_N PF00350.23 RUS70443.1 - 0.021 14.9 0.1 0.071 13.2 0.1 1.8 1 1 0 1 1 1 0 Dynamin family DUF87 PF01935.17 RUS70443.1 - 0.072 13.2 1.7 5 7.2 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 RUS70443.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 RUS70443.1 - 0.084 12.1 0.0 0.76 9.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 RUS70443.1 - 0.13 12.6 0.1 0.25 11.6 0.1 1.7 1 1 1 2 2 2 0 AAA domain Microtub_bd PF16796.5 RUS70444.1 - 2e-05 24.6 0.0 4.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding SSXT PF05030.12 RUS70444.1 - 0.062 12.9 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) CBM_26 PF16824.5 RUS70444.1 - 0.076 13.2 0.5 0.097 12.8 0.5 1.1 1 0 0 1 1 1 0 C-terminal carbohydrate-binding module MPS2 PF17060.5 RUS70444.1 - 0.64 9.2 4.5 0.69 9.1 4.5 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 CENP-H PF05837.12 RUS70444.1 - 1.5 9.2 8.7 2.9 8.3 8.7 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) F_actin_cap_B PF01115.17 RUS70445.1 - 1.9e-105 351.7 0.0 2.2e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 RUS70445.1 - 0.041 13.3 0.1 0.091 12.2 0.1 1.8 1 1 0 1 1 1 0 F-actin capping protein alpha subunit RRN3 PF05327.11 RUS70447.1 - 2.9e-34 118.5 0.5 3.6e-34 118.2 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Glycos_transf_2 PF00535.26 RUS70448.1 - 4.8e-31 107.8 0.0 7.7e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS70448.1 - 3.2e-16 59.7 1.6 5.9e-16 58.9 1.6 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RUS70448.1 - 6e-08 32.8 0.0 1.2e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS70448.1 - 1.1e-07 31.4 1.3 1.7e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS70448.1 - 1.8e-06 27.6 0.0 9.8e-06 25.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 DUF951 PF06107.11 RUS70448.1 - 0.081 12.9 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Pkinase PF00069.25 RUS70449.1 - 1.7e-72 243.9 0.0 2.8e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70449.1 - 2.2e-35 122.2 0.0 3.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS70449.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS70449.1 - 0.00066 18.6 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS70449.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SatRNA_48 PF17485.2 RUS70449.1 - 0.048 12.8 0.1 0.077 12.1 0.1 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein APH PF01636.23 RUS70449.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RUS70449.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SPATA48 PF15073.6 RUS70450.1 - 5.7e-42 143.0 1.7 9.9e-42 142.3 1.7 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Ank_2 PF12796.7 RUS70451.1 - 9.8e-08 32.5 0.8 0.012 16.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ion_trans PF00520.31 RUS70451.1 - 1.2e-05 24.7 19.0 1.2e-05 24.7 19.0 2.2 2 1 0 2 2 2 1 Ion transport protein Ank_4 PF13637.6 RUS70451.1 - 8.4e-05 23.1 0.1 0.51 11.0 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS70451.1 - 0.00064 20.0 0.2 12 6.8 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 RUS70451.1 - 0.0032 17.9 0.7 48 4.6 0.2 4.9 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 RUS70451.1 - 0.11 12.8 0.6 59 4.1 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) RT_RNaseH_2 PF17919.1 RUS70453.1 - 7.6e-34 115.7 0.0 1.4e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS70453.1 - 2.6e-33 114.5 0.0 5.1e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS70453.1 - 4.8e-22 78.6 0.1 7.7e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS70453.1 - 3.9e-18 65.8 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS70453.1 - 1.1e-12 47.8 0.1 2.5e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Ion_trans PF00520.31 RUS70453.1 - 1e-07 31.4 0.0 1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Ion transport protein DDE_3 PF13358.6 RUS70453.1 - 0.02 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease rve_3 PF13683.6 RUS70453.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain KH_1 PF00013.29 RUS70455.1 - 3.4e-37 126.1 10.5 1.4e-12 47.2 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RUS70455.1 - 2.9e-12 46.2 11.9 0.00013 21.7 0.5 4.1 3 1 1 4 4 4 3 KH domain KH_5 PF13184.6 RUS70455.1 - 1.9e-06 27.9 3.1 0.52 10.4 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 RUS70455.1 - 1.9e-05 24.5 9.6 0.019 14.8 0.1 3.3 3 0 0 3 3 3 2 KH domain Laminin_G_2 PF02210.24 RUS70456.1 - 2.1e-46 157.6 0.1 1.1e-23 84.2 0.0 3.4 3 0 0 3 3 3 2 Laminin G domain Cadherin_C PF01049.17 RUS70456.1 - 2e-36 125.5 4.1 3.2e-36 124.8 4.1 1.3 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_1 PF00054.23 RUS70456.1 - 3.3e-28 98.5 0.0 1.3e-13 51.3 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Cadherin PF00028.17 RUS70456.1 - 8.3e-10 39.0 0.2 0.0015 18.9 0.1 2.7 2 0 0 2 2 2 2 Cadherin domain EGF PF00008.27 RUS70456.1 - 1.5e-05 25.2 45.5 0.00023 21.4 6.1 4.7 4 0 0 4 4 4 2 EGF-like domain Adeno_E3_CR2 PF02439.15 RUS70456.1 - 0.0005 19.8 0.1 0.0009 19.0 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 hEGF PF12661.7 RUS70456.1 - 0.0036 17.9 3.2 0.0036 17.9 3.2 5.0 4 0 0 4 4 4 1 Human growth factor-like EGF TMEM154 PF15102.6 RUS70456.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Invasin_D3 PF09134.10 RUS70456.1 - 0.068 13.5 0.4 10 6.5 0.1 3.3 3 0 0 3 3 3 0 Invasin, domain 3 DUF4219 PF13961.6 RUS70457.1 - 1.5e-52 174.5 124.8 62 3.4 0.0 58.0 60 0 0 60 60 60 0 Domain of unknown function (DUF4219) Peptidase_S8 PF00082.22 RUS70457.1 - 1e-15 57.8 88.0 1 8.6 2.1 13.9 1 1 2 3 3 3 1 Subtilase family TT1725 PF18324.1 RUS70457.1 - 3.3e-15 56.1 33.7 13 5.9 0.2 15.3 1 1 16 17 17 17 13 Hypothetical protein TT1725 LicD PF04991.13 RUS70458.1 - 1.7e-15 57.8 2.5 2e-14 54.3 0.6 3.0 3 1 0 3 3 3 1 LicD family SRCR PF00530.18 RUS70459.1 - 5.5e-187 607.6 65.5 1.5e-25 89.6 1.6 11.2 11 0 0 11 11 11 11 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS70459.1 - 2.6e-42 143.3 51.8 6.2e-06 26.7 1.5 11.5 11 0 0 11 11 11 9 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS70459.1 - 3.5e-19 69.3 22.3 0.052 14.1 0.2 10.6 10 0 0 10 10 10 6 Hepsin, SRCR domain Syndecan PF01034.20 RUS70459.1 - 0.02 14.8 0.4 0.038 13.9 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 RUS70459.1 - 0.11 12.3 3.4 0.29 11.0 3.4 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 RUS70459.1 - 0.24 10.1 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) cEGF PF12662.7 RUS70459.1 - 0.85 9.6 6.8 2.2 8.3 1.3 4.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like MRP_L53 PF10780.9 RUS70459.1 - 1.3 9.3 3.4 3.8 7.8 3.4 1.8 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DUF1180 PF06679.12 RUS70459.1 - 1.8 8.9 8.1 3.7 8.0 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SRCR PF00530.18 RUS70460.1 - 1.5e-46 157.0 7.0 5.4e-18 65.3 0.1 3.1 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS70460.1 - 7.4e-18 64.9 4.0 5.4e-07 30.1 0.2 3.3 3 0 0 3 3 3 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS70460.1 - 2e-09 37.9 2.0 0.00079 19.9 0.0 3.3 3 0 0 3 3 3 3 Hepsin, SRCR domain PK_C PF02887.16 RUS70461.1 - 4.8e-17 62.3 0.0 5.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Med19 PF10278.9 RUS70462.1 - 0.12 12.3 9.0 0.33 10.9 9.0 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 V_ATPase_I PF01496.19 RUS70462.1 - 5.3 4.8 13.5 8.4 4.2 13.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIP5K PF01504.18 RUS70462.1 - 6 6.0 8.4 16 4.6 8.4 1.8 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase KAAG1 PF15354.6 RUS70463.1 - 0.38 11.3 10.1 3.7 8.1 0.9 3.2 1 1 0 2 2 2 0 Kidney-associated antigen 1 ALP_N PF17989.1 RUS70465.1 - 1e-08 35.5 6.4 1.9 8.6 0.1 6.7 1 1 6 7 7 7 6 Actin like proteins N terminal domain UBX PF00789.20 RUS70465.1 - 8.1e-06 26.0 7.4 6.1 7.1 0.5 5.6 1 1 5 6 6 6 6 UBX domain Vps39_1 PF10366.9 RUS70465.1 - 0.00014 22.1 12.8 6.7 7.0 0.9 5.9 1 1 5 6 6 6 5 Vacuolar sorting protein 39 domain 1 IL17R_fnIII_D2 PF16578.5 RUS70465.1 - 0.15 12.6 7.8 32 5.1 0.3 3.5 1 1 4 5 5 5 0 Interleukin 17 receptor D DUF3034 PF11231.8 RUS70465.1 - 0.52 9.8 4.3 9.4 5.7 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3034) DHC_N2 PF08393.13 RUS70466.1 - 1e-05 24.8 0.4 1.9e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 YIF1 PF03878.15 RUS70466.1 - 0.067 12.7 0.6 0.11 12.0 0.6 1.3 1 0 0 1 1 1 0 YIF1 RVT_thumb PF06817.14 RUS70466.1 - 0.11 12.4 0.0 23 4.9 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase thumb domain CHCH PF06747.13 RUS70467.1 - 1.9e-10 40.6 9.8 0.85 9.8 0.1 7.2 1 1 6 8 8 8 7 CHCH domain DUF5113 PF17140.4 RUS70467.1 - 0.004 17.0 7.3 0.61 9.9 1.5 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF5113) SF3A3 PF16837.5 RUS70467.1 - 0.023 15.2 3.9 3.4 8.3 3.9 3.1 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 UPF0203 PF05254.12 RUS70467.1 - 0.05 13.8 13.9 1.4 9.2 4.4 3.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) TM2 PF05154.16 RUS70467.1 - 0.31 11.4 14.7 13 6.2 0.6 5.4 2 2 2 5 5 5 0 TM2 domain COX6B PF02297.17 RUS70467.1 - 2.9 8.2 12.6 3.1e+03 -1.5 12.6 3.8 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 RUS70467.1 - 9 6.8 13.0 82 3.7 0.2 3.9 1 1 1 2 2 2 0 GCK domain DHC_N2 PF08393.13 RUS70468.1 - 2.8e-05 23.4 0.0 0.0041 16.3 0.0 2.1 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 DUF1459 PF07312.11 RUS70468.1 - 0.0015 18.7 0.0 1.8 8.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1459) DUF3253 PF11625.8 RUS70468.1 - 0.044 14.0 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Ribosomal_L4 PF00573.22 RUS70469.1 - 1.7e-45 155.1 0.0 2.2e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family HYLS1_C PF15311.6 RUS70470.1 - 2.7e-18 66.5 8.0 5.1e-18 65.6 8.0 1.5 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus Transposase_1 PF01359.18 RUS70472.1 - 2.1e-19 69.1 0.0 5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS70472.1 - 5.1e-08 32.8 0.0 8.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS70472.1 - 3.4e-05 24.0 0.2 8.2e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS70472.1 - 0.014 15.4 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS70472.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 RUS70472.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 PCI domain HTH_26 PF13443.6 RUS70472.1 - 0.086 13.3 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF2650 PF10853.8 RUS70474.1 - 0.048 13.4 1.2 0.12 12.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Lectin_C PF00059.21 RUS70475.1 - 6.6e-31 107.2 1.8 1e-15 58.4 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 RUS70476.1 - 4.7e-20 72.3 0.1 1.3e-19 70.9 0.1 1.9 1 0 0 1 1 1 1 Lectin C-type domain RVT_1 PF00078.27 RUS70476.1 - 0.00011 21.8 0.4 0.00017 21.2 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4079 PF13301.6 RUS70476.1 - 0.025 14.7 0.7 0.36 11.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF5494 PF17598.2 RUS70477.1 - 0.31 11.2 10.0 42 4.3 0.0 5.9 1 1 5 8 8 8 0 Family of unknown function (DUF5494) Baculo_PEP_C PF04513.12 RUS70478.1 - 0.0027 17.7 0.0 0.029 14.4 0.0 2.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_SSB PF16773.5 RUS70478.1 - 0.16 12.0 0.1 0.64 10.1 0.1 2.0 1 1 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein SeqA_N PF17206.3 RUS70478.1 - 2.6 7.4 24.2 19 4.7 0.1 6.2 2 1 7 9 9 9 0 SeqA protein N-terminal domain ADAM_CR PF08516.12 RUS70481.1 - 0.16 12.3 0.7 23 5.4 0.1 2.3 1 1 1 2 2 2 0 ADAM cysteine-rich DUF1638 PF07796.11 RUS70481.1 - 0.28 11.3 2.7 7.5 6.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1638) Exo_endo_phos_2 PF14529.6 RUS70482.1 - 2.4e-10 40.3 1.5 3.9e-10 39.6 0.2 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase ArnB_C PF18677.1 RUS70483.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain TAF1D PF15333.6 RUS70483.1 - 0.57 9.9 6.6 0.41 10.4 4.4 1.9 1 1 1 2 2 2 0 TATA box-binding protein-associated factor 1D Voltage_CLC PF00654.20 RUS70485.1 - 5.4e-92 308.8 21.5 1.8e-91 307.1 19.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RUS70485.1 - 6.9e-09 36.0 0.0 0.0067 16.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 RUS70485.1 - 2.4 8.2 11.3 0.029 14.2 3.2 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Molydop_binding PF01568.21 RUS70486.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Na_Ca_ex PF01699.24 RUS70487.1 - 8.3e-45 152.4 32.9 5.3e-24 84.9 11.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 RUS70487.1 - 5.1e-33 113.2 0.0 4.9e-15 55.5 0.0 2.8 2 1 0 2 2 2 2 Calx-beta domain SSF PF00474.17 RUS70489.1 - 1.4e-27 96.6 29.7 1.4e-27 96.6 29.7 2.0 2 1 0 2 2 2 1 Sodium:solute symporter family Phage_holin_Dp1 PF16938.5 RUS70489.1 - 2.9 8.2 7.8 0.52 10.5 1.6 3.1 3 0 0 3 3 3 0 Putative phage holin Dp-1 Claudin_2 PF13903.6 RUS70490.1 - 1 9.1 3.6 0.32 10.7 0.1 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IRF PF00605.17 RUS70491.1 - 3.6e-21 75.4 0.3 3.6e-21 75.4 0.3 1.6 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor Sas10 PF09368.10 RUS70493.1 - 1.2e-18 67.3 8.2 1.2e-18 67.3 8.2 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain MepB PF08877.10 RUS70494.1 - 0.18 11.5 0.1 0.39 10.4 0.0 1.6 1 1 0 1 1 1 0 MepB protein UbiA PF01040.18 RUS70495.1 - 3.2e-57 193.7 13.7 4.4e-57 193.3 13.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family tRNA-synt_2 PF00152.20 RUS70496.1 - 1.3e-92 310.3 0.0 1.6e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 RUS70496.1 - 0.0006 20.0 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 RUS70496.1 - 0.0082 15.6 0.0 0.096 12.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 RUS70496.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) LRR_8 PF13855.6 RUS70497.1 - 1.7e-66 219.9 66.6 1.3e-14 53.7 0.4 10.6 5 2 5 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 RUS70497.1 - 1.4e-44 149.3 62.0 9.6e-06 25.9 5.9 14.4 10 5 3 15 15 15 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS70497.1 - 4.2e-22 75.3 43.0 2.2 9.2 0.0 20.6 21 1 0 21 21 21 4 Leucine Rich Repeat LRR_6 PF13516.6 RUS70497.1 - 2.9e-12 45.6 69.1 0.5 10.6 2.9 19.6 23 0 0 23 23 23 6 Leucine Rich repeat LRR_5 PF13306.6 RUS70497.1 - 1.5e-11 44.3 0.1 0.008 16.1 0.0 4.9 5 0 0 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS70497.1 - 2e-08 33.9 13.3 0.021 14.3 0.4 5.7 4 2 1 5 5 5 3 Leucine-rich repeat Vpu PF00558.19 RUS70497.1 - 0.0089 15.8 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Vpu protein Baculo_11_kDa PF06143.11 RUS70497.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4381 PF14316.6 RUS70497.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 RUS70497.1 - 0.14 12.0 0.3 0.34 10.8 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain LRRNT PF01462.18 RUS70497.1 - 2.4 7.9 6.0 1.3 8.8 1.9 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain OST-HTH PF12872.7 RUS70498.1 - 1.1e-23 82.8 0.0 2.6e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 OST-HTH/LOTUS domain zf-B_box PF00643.24 RUS70499.1 - 0.00035 20.7 4.0 0.00035 20.7 4.0 2.2 2 0 0 2 2 2 1 B-box zinc finger Zn_ribbon_SprT PF17283.2 RUS70499.1 - 1.2 9.1 7.0 5.1 7.1 0.0 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-RING_UBOX PF13445.6 RUS70500.1 - 1.1e-08 35.0 2.4 1.1e-08 35.0 2.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS70500.1 - 3.2e-08 33.3 4.7 4.2e-08 32.9 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS70500.1 - 2e-06 27.8 6.9 2.8e-06 27.4 2.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS70500.1 - 4.6e-05 23.2 5.3 4.6e-05 23.2 5.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS70500.1 - 0.00035 20.5 7.8 0.0016 18.4 3.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS70500.1 - 0.0005 20.3 8.4 0.0023 18.2 5.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS70500.1 - 0.00059 19.6 8.1 0.001 18.9 4.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS70500.1 - 0.0035 17.2 7.7 0.03 14.2 4.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 RUS70500.1 - 0.0079 16.0 0.1 0.056 13.3 0.1 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DNA_ligase_ZBD PF03119.16 RUS70500.1 - 0.012 15.7 2.6 0.058 13.4 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_Tnp_IS91 PF14319.6 RUS70500.1 - 0.032 14.3 1.5 0.25 11.4 0.5 2.1 2 0 0 2 2 2 0 Transposase zinc-binding domain TF_Zn_Ribbon PF08271.12 RUS70500.1 - 0.069 12.7 4.7 0.12 11.9 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding TALPID3 PF15324.6 RUS70500.1 - 0.075 10.7 5.1 0.088 10.5 5.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target U-box PF04564.15 RUS70500.1 - 0.084 13.1 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 RUS70500.1 - 0.12 12.3 4.1 0.2 11.6 1.9 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Elf1 PF05129.13 RUS70500.1 - 0.13 12.3 0.9 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 RUS70500.1 - 0.23 12.0 1.8 5.5 7.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DZR PF12773.7 RUS70500.1 - 0.27 11.3 4.8 9.6 6.3 2.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 RUS70500.1 - 0.64 9.7 0.1 0.64 9.7 0.1 2.6 3 0 0 3 3 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_5 PF17121.5 RUS70500.1 - 0.67 9.9 7.1 22 5.0 4.2 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 RUS70500.1 - 0.74 9.6 0.1 0.74 9.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 RUS70500.1 - 1.1 9.2 5.1 16 5.5 2.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1178 PF06676.11 RUS70500.1 - 6.9 7.0 5.1 22 5.4 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) DUF4349 PF14257.6 RUS70501.1 - 0.13 11.7 0.7 0.26 10.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ferritin PF00210.24 RUS70504.1 - 8.6e-12 45.2 0.1 1.4e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain VWD PF00094.25 RUS70505.1 - 7.7e-17 62.0 5.7 1.6e-15 57.7 2.2 2.5 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 RUS70505.1 - 9.1e-15 54.8 2.3 9.1e-15 54.8 2.3 3.8 3 1 0 3 3 3 1 C8 domain Lectin_C PF00059.21 RUS70505.1 - 1.2e-12 48.5 16.3 2.5e-10 41.0 1.3 5.0 4 0 0 4 4 4 2 Lectin C-type domain EGF_CA PF07645.15 RUS70505.1 - 4.3e-09 36.4 8.9 4.3e-09 36.4 8.9 6.1 6 0 0 6 6 6 1 Calcium-binding EGF domain TIL PF01826.17 RUS70505.1 - 2.2e-05 24.6 9.3 2.2e-05 24.6 9.3 6.0 4 2 1 5 5 5 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 RUS70505.1 - 0.0019 18.3 3.6 0.0019 18.3 3.6 7.0 8 1 0 8 8 8 1 EGF domain Lectin_C PF00059.21 RUS70506.1 - 0.053 14.3 0.0 6.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Lectin C-type domain NUDIX PF00293.28 RUS70507.1 - 0.0024 17.9 0.0 0.009 16.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain CCCAP PF15964.5 RUS70508.1 - 1.5e-83 281.3 92.9 8.8e-82 275.5 92.9 2.4 1 1 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family T2SSG PF08334.11 RUS70508.1 - 0.013 15.5 0.8 3.5 7.7 0.2 3.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G DUF285 PF03382.14 RUS70508.1 - 0.065 13.0 2.3 0.2 11.4 2.3 1.8 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 TPR_MLP1_2 PF07926.12 RUS70508.1 - 0.32 11.0 94.0 0.029 14.4 13.9 7.1 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 RUS70508.1 - 2 8.7 38.5 0.79 10.0 0.6 8.2 7 1 1 8 8 8 0 Homeobox associated leucine zipper DASH_Hsk3 PF08227.11 RUS70508.1 - 3.8 8.0 0.0 3.8 8.0 0.0 5.4 6 0 0 6 6 6 0 DASH complex subunit Hsk3 like WAP PF00095.21 RUS70509.1 - 5.1e-12 46.0 39.9 4.7e-09 36.5 17.1 5.2 4 2 1 5 5 5 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Nop14 PF04147.12 RUS70510.1 - 0.55 8.4 55.1 0.69 8.0 55.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.6 RUS70510.1 - 5 6.7 31.7 6.9 6.2 31.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SID-1_RNA_chan PF13965.6 RUS70510.1 - 5 5.4 15.6 6.5 5.0 15.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4402 PF14352.6 RUS70511.1 - 0.1 13.3 1.4 1.3 9.6 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) EF-hand_11 PF08976.11 RUS70512.1 - 1.7e-74 247.4 19.0 1e-16 61.7 0.0 12.2 12 0 0 12 12 12 10 EF-hand domain EF-hand_7 PF13499.6 RUS70512.1 - 3.8e-51 171.4 54.8 3.3e-06 27.4 3.6 14.1 13 1 0 13 13 13 8 EF-hand domain pair EF-hand_1 PF00036.32 RUS70512.1 - 4.4e-48 157.3 30.6 4e-05 22.9 0.2 17.1 18 0 0 18 18 18 12 EF hand EF-hand_6 PF13405.6 RUS70512.1 - 2.4e-47 154.9 47.9 0.0002 21.0 0.3 18.1 19 0 0 19 19 18 12 EF-hand domain EF-hand_5 PF13202.6 RUS70512.1 - 1.4e-23 81.2 3.7 1.9e-05 24.0 0.1 7.9 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 RUS70512.1 - 8.7e-20 70.3 13.5 0.0019 18.0 0.0 13.8 15 1 1 16 16 15 4 EF-hand domain pair EF-hand_9 PF14658.6 RUS70512.1 - 9.9e-08 32.2 5.4 0.54 10.6 0.1 8.3 10 0 0 10 10 9 1 EF-hand domain EF-hand_4 PF12763.7 RUS70512.1 - 0.0017 18.3 1.4 0.36 10.8 0.0 4.6 5 0 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 RUS70512.1 - 0.014 14.0 4.8 1.1 7.8 0.0 4.4 4 1 0 5 5 5 0 Family of unknown function (DUF5580) GPHH PF16905.5 RUS70512.1 - 0.029 14.1 0.0 1.9 8.3 0.0 3.6 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated Terminase_6 PF03237.15 RUS70512.1 - 0.033 13.9 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 Terminase-like family Herpes_BLRF2 PF05812.12 RUS70512.1 - 0.034 14.3 4.2 7.6 6.7 0.0 5.6 6 0 0 6 6 5 0 Herpesvirus BLRF2 protein Dockerin_1 PF00404.18 RUS70512.1 - 0.044 14.0 2.9 21 5.4 0.0 5.2 6 0 0 6 6 6 0 Dockerin type I domain RST PF12174.8 RUS70512.1 - 0.08 12.9 1.3 19 5.3 0.0 4.5 6 0 0 6 6 5 0 RCD1-SRO-TAF4 (RST) plant domain EFhand_Ca_insen PF08726.10 RUS70512.1 - 0.1 12.7 9.3 2.4 8.3 0.2 5.1 5 0 0 5 5 4 0 Ca2+ insensitive EF hand Erf4 PF10256.9 RUS70512.1 - 0.42 10.7 3.9 9.8 6.3 0.1 4.3 4 1 1 5 5 4 0 Golgin subfamily A member 7/ERF4 family TerB PF05099.13 RUS70512.1 - 0.45 10.5 5.0 1.5 8.8 0.2 3.8 4 0 0 4 4 4 0 Tellurite resistance protein TerB VPS13 PF16908.5 RUS70512.1 - 0.73 9.6 3.9 4.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Vacuolar sorting-associated protein 13, N-terminal EF-hand_14 PF17959.1 RUS70512.1 - 1.2 9.5 9.3 9.6 6.6 0.1 5.3 6 0 0 6 6 5 0 EF-hand domain Caleosin PF05042.13 RUS70512.1 - 2.9 7.8 7.7 5.5 6.9 0.1 5.3 7 0 0 7 7 6 0 Caleosin related protein DoxX_2 PF13564.6 RUS70514.1 - 8.3e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 DoxX-like family SafA PF17073.5 RUS70514.1 - 0.57 10.2 4.5 7.1 6.7 0.0 3.0 2 1 1 3 3 3 0 Two-component-system connector protein DRIM PF07539.12 RUS70515.1 - 2.5e-157 524.9 6.4 2.5e-157 524.9 6.4 4.0 3 1 0 3 3 3 2 Down-regulated in metastasis MMS19_N PF14500.6 RUS70515.1 - 0.024 14.2 0.1 0.024 14.2 0.1 6.4 8 1 1 9 9 9 0 Dos2-interacting transcription regulator of RNA-Pol-II NYD-SP28 PF14772.6 RUS70515.1 - 0.031 14.3 0.1 0.27 11.3 0.0 2.6 2 0 0 2 2 2 0 Sperm tail IFRD PF05004.13 RUS70515.1 - 0.55 9.3 6.8 3.3 6.7 0.0 4.7 5 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) FANCI_S2 PF14676.6 RUS70515.1 - 0.77 10.1 7.0 0.52 10.6 0.2 4.3 5 0 0 5 5 5 0 FANCI solenoid 2 Xpo1 PF08389.12 RUS70515.1 - 2 8.5 5.6 71 3.4 0.1 5.2 4 0 0 4 4 4 0 Exportin 1-like protein PBP1_TM PF14812.6 RUS70515.1 - 9.3 6.7 6.3 0.95 9.9 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dapper PF15268.6 RUS70516.1 - 3.2 6.5 61.5 5.4 5.7 61.5 1.2 1 0 0 1 1 1 0 Dapper Somatomedin_B PF01033.17 RUS70517.1 - 0.00023 21.5 10.6 0.00023 21.5 10.6 2.5 3 0 0 3 3 3 1 Somatomedin B domain Nop14 PF04147.12 RUS70517.1 - 0.25 9.5 31.4 0.46 8.6 31.4 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS70517.1 - 1.1 8.0 14.8 2.1 7.0 14.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS70517.1 - 1.1 8.6 34.1 1.9 7.8 34.1 1.3 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 RUS70518.1 - 3.5e-11 43.4 4.9 1.1e-05 26.0 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 RUS70518.1 - 0.0026 16.5 2.2 0.061 11.9 0.1 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS70518.1 - 0.095 12.0 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain Na_K-ATPase PF00287.18 RUS70519.1 - 1.4e-23 83.5 0.1 1.6e-23 83.3 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Na_K-ATPase PF00287.18 RUS70521.1 - 5.3e-17 61.9 0.0 5.8e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Na_K-ATPase PF00287.18 RUS70522.1 - 4.4e-70 236.1 0.0 5e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain N_BRCA1_IG PF16158.5 RUS70523.1 - 9.9e-28 96.9 0.1 1.8e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 RUS70523.1 - 8.7e-13 47.9 0.6 1.8e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 UBA-like domain CARDB PF07705.11 RUS70523.1 - 0.00035 20.8 0.0 0.00066 19.9 0.0 1.4 1 0 0 1 1 1 1 CARDB Scramblase PF03803.15 RUS70524.1 - 2.8e-23 82.4 0.0 3.2e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Scramblase Med1 PF10744.9 RUS70524.1 - 0.004 16.3 0.0 0.0044 16.1 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 KaiA PF07688.12 RUS70526.1 - 0.093 12.9 2.6 0.27 11.4 2.3 2.0 1 1 0 1 1 1 0 KaiA C-terminal domain DUF1599 PF07659.11 RUS70526.1 - 0.78 10.2 2.6 46 4.6 0.0 3.4 3 1 0 3 3 3 0 Nucleotide modification associated domain 1 TPP_enzyme_N PF02776.18 RUS70527.1 - 8.2e-50 168.8 1.6 8.2e-50 168.8 1.6 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 RUS70527.1 - 3e-26 92.0 0.0 8e-25 87.4 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 RUS70527.1 - 1.8e-18 66.6 0.0 1.4e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain zf-RAG1 PF10426.9 RUS70528.1 - 1.3e-09 38.0 0.0 2.1 8.5 0.0 6.6 7 0 0 7 7 7 3 Recombination-activating protein 1 zinc-finger domain Sushi PF00084.20 RUS70528.1 - 2.9e-08 34.2 5.5 7.2 7.3 0.0 5.6 1 1 4 5 5 5 5 Sushi repeat (SCR repeat) Cbl_N2 PF02761.14 RUS70528.1 - 0.00025 21.7 0.0 0.14 12.9 0.0 3.0 1 1 1 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain DUF493 PF04359.14 RUS70528.1 - 0.0025 18.3 2.5 1.5e+02 3.0 0.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF493) zf-CXXC PF02008.20 RUS70528.1 - 0.79 9.8 4.3 45 4.2 0.1 3.8 1 1 3 5 5 5 0 CXXC zinc finger domain CPW_WPC PF09717.10 RUS70528.1 - 2.3 9.3 14.4 46 5.1 0.9 5.1 1 1 1 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) AMP-binding PF00501.28 RUS70530.1 - 4.8e-27 94.6 0.0 9.2e-27 93.7 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme DMAP_binding PF06464.11 RUS70530.1 - 4.6e-07 30.6 1.8 1.4e-06 29.1 1.8 1.9 1 1 0 1 1 1 1 DMAP1-binding Domain Arginosuc_synth PF00764.19 RUS70531.1 - 7.9e-77 259.1 0.0 8.9e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase SAPS PF04499.15 RUS70533.1 - 2.7 6.7 10.8 3 6.5 10.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS70533.1 - 2.8 6.0 42.5 3.4 5.8 42.5 1.0 1 0 0 1 1 1 0 Nop14-like family Beta_helix PF13229.6 RUS70534.1 - 8.1e-06 25.8 35.7 0.00065 19.6 12.9 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 RUS70534.1 - 4.2e-05 22.9 15.2 0.00063 19.1 4.2 1.9 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) XET_C PF06955.12 RUS70534.1 - 0.0018 18.0 0.2 1.2e+02 2.6 0.0 5.4 6 0 0 6 6 6 0 Xyloglucan endo-transglycosylase (XET) C-terminus DUF826 PF05696.11 RUS70534.1 - 0.0032 17.5 0.0 54 4.0 0.0 4.5 1 1 3 5 5 5 0 Protein of unknown function (DUF826) DUF424 PF04242.13 RUS70534.1 - 0.0086 16.3 4.0 0.11 12.8 0.2 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF424) Ribosomal_L9_C PF03948.14 RUS70534.1 - 0.18 12.3 1.8 7.4 7.1 0.2 3.0 1 1 1 3 3 3 0 Ribosomal protein L9, C-terminal domain SR1P PF13790.6 RUS70534.1 - 0.2 11.8 13.8 84 3.4 0.0 6.6 6 3 0 6 6 6 0 SR1 protein HTH_28 PF13518.6 RUS70534.1 - 0.26 11.5 0.6 1.6e+02 2.5 0.0 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain S-AdoMet_synt_M PF02772.16 RUS70534.1 - 9.9 6.5 8.4 77 3.6 0.3 3.1 1 1 2 3 3 3 0 S-adenosylmethionine synthetase, central domain Ribosomal_L9_N PF01281.19 RUS70535.1 - 5.4e-13 48.3 0.0 7.9e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Fasciclin PF02469.22 RUS70536.1 - 1.3e-07 31.8 0.0 1.6e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 RUS70537.1 - 5.1e-45 152.8 3.0 7.2e-15 55.3 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain Fasciclin PF02469.22 RUS70538.1 - 5.3e-09 36.4 0.0 2.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain BTB_2 PF02214.22 RUS70539.1 - 2.9e-18 66.0 0.0 1e-17 64.2 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain DUSP PF06337.12 RUS70539.1 - 3.9e-06 27.4 0.3 0.00032 21.3 0.3 2.7 1 1 0 1 1 1 1 DUSP domain Ubiquitin_3 PF14836.6 RUS70539.1 - 0.00017 21.5 0.0 0.00049 20.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain BTB_3 PF16017.5 RUS70539.1 - 0.0009 19.3 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FapA PF03961.13 RUS70539.1 - 0.18 10.4 9.6 0.24 9.9 9.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 RUS70539.1 - 0.52 9.9 11.9 1.2 8.7 11.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Exonuc_VII_L PF02601.15 RUS70539.1 - 5.7 6.4 8.3 8.7 5.8 8.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4337 PF14235.6 RUS70539.1 - 9.4 6.3 7.7 15 5.6 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Orthoreo_P10 PF07204.11 RUS70540.1 - 0.017 15.0 0.2 0.037 14.0 0.3 1.6 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Thiolase_N PF00108.23 RUS70541.1 - 0.00078 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ISK_Channel PF02060.15 RUS70542.1 - 0.00036 20.2 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DEK_C PF08766.11 RUS70543.1 - 1.7e-17 63.1 0.3 5.5e-17 61.4 0.3 2.0 1 0 0 1 1 1 1 DEK C terminal domain Nop14 PF04147.12 RUS70543.1 - 0.025 12.8 63.1 0.015 13.6 35.8 2.3 2 0 0 2 2 2 0 Nop14-like family TFIIF_alpha PF05793.12 RUS70543.1 - 3.4 6.1 83.5 0.12 11.0 51.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 RUS70543.1 - 8.7 6.2 57.2 4.6 7.1 41.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal KIND PF16474.5 RUS70545.1 - 2.7e-15 56.8 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain DUF4805 PF16063.5 RUS70545.1 - 0.12 11.7 5.8 0.15 11.4 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Galactosyl_T PF01762.21 RUS70546.1 - 7.4e-14 52.0 0.1 1.4e-13 51.1 0.1 1.4 1 1 0 1 1 1 1 Galactosyltransferase Mic1 PF07035.12 RUS70547.1 - 0.081 12.6 0.9 12 5.6 0.0 4.3 2 2 4 7 7 7 0 Colon cancer-associated protein Mic1-like YliH PF10799.8 RUS70547.1 - 0.46 10.4 3.5 38 4.2 0.1 4.8 2 1 1 4 4 4 0 Biofilm formation protein (YliH/bssR) DUF305 PF03713.13 RUS70547.1 - 0.67 10.1 7.9 4.4 7.4 3.9 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF305) DUF1774 PF08611.10 RUS70548.1 - 0.007 16.7 5.7 41 4.6 0.1 5.4 1 1 5 6 6 6 3 Fungal protein of unknown function (DUF1774) COesterase PF00135.28 RUS70549.1 - 3.4e-81 273.7 0.0 3.8e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family NPIP PF06409.11 RUS70549.1 - 0.044 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Podoplanin PF05808.11 RUS70551.1 - 6.2 6.9 18.0 2 8.5 5.8 2.1 1 1 1 2 2 2 0 Podoplanin Acyl_transf_3 PF01757.22 RUS70552.1 - 1.9e-18 66.7 22.6 1.9e-18 66.7 22.6 1.7 2 0 0 2 2 2 1 Acyltransferase family ECF-ribofla_trS PF07155.12 RUS70552.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.1 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component Lectin_C PF00059.21 RUS70553.1 - 0.013 16.2 0.0 0.019 15.7 0.0 1.3 1 0 0 1 1 1 0 Lectin C-type domain DUF3357 PF11837.8 RUS70554.1 - 1.4 9.4 3.6 5.4 7.5 0.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) WAP PF00095.21 RUS70556.1 - 4.6e-08 33.3 15.2 4.6e-08 33.3 15.2 5.2 5 1 0 5 5 5 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Lustrin_cystein PF14625.6 RUS70556.1 - 0.024 15.0 4.4 0.024 15.0 4.4 6.7 5 2 1 6 6 6 0 Lustrin, cysteine-rich repeated domain Ran_BP1 PF00638.18 RUS70561.1 - 0.071 13.4 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 RanBP1 domain Es2 PF09751.9 RUS70562.1 - 1.1e-76 259.4 9.5 1.1e-76 259.4 9.5 2.3 2 1 0 2 2 2 1 Nuclear protein Es2 ERp29_N PF07912.13 RUS70563.1 - 2.5e-35 121.4 0.2 5.8e-35 120.2 0.2 1.6 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 RUS70563.1 - 4.6e-25 88.4 1.1 9.5e-25 87.3 1.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_6 PF13848.6 RUS70563.1 - 0.0054 16.7 0.2 0.0099 15.8 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Phage_CI_repr PF07022.13 RUS70563.1 - 0.045 13.8 0.0 0.43 10.7 0.0 2.4 1 1 1 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DUF134 PF02001.16 RUS70563.1 - 0.067 13.8 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF134 SKA2 PF16740.5 RUS70564.1 - 7.8e-17 61.0 2.6 7.8e-17 61.0 2.6 1.8 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF3161 PF11362.8 RUS70564.1 - 2.7e-14 52.9 0.0 5.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 RUS70564.1 - 4.5e-07 30.0 2.2 7.5e-07 29.2 2.2 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Tup_N PF08581.10 RUS70564.1 - 0.0068 16.7 1.1 0.018 15.4 1.1 1.8 1 0 0 1 1 1 1 Tup N-terminal Vps51 PF08700.11 RUS70564.1 - 0.038 14.1 0.6 0.12 12.5 0.6 1.8 1 0 0 1 1 1 0 Vps51/Vps67 DUF2278 PF10042.9 RUS70564.1 - 0.057 13.4 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TctA PF01970.16 RUS70564.1 - 0.076 11.7 0.3 0.099 11.3 0.3 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Spc7 PF08317.11 RUS70564.1 - 0.43 9.4 6.1 0.051 12.5 1.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 RUS70564.1 - 0.74 10.7 11.1 1.1 10.2 1.7 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TRAM_LAG1_CLN8 PF03798.16 RUS70565.1 - 1.3e-16 60.9 33.8 1.3e-16 60.9 33.8 1.4 2 0 0 2 2 2 1 TLC domain Sugar_tr PF00083.24 RUS70566.1 - 6e-37 127.6 12.3 8e-37 127.1 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS70566.1 - 7.2e-06 25.2 25.2 1.1e-05 24.5 25.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BTB PF00651.31 RUS70567.1 - 7.9e-24 84.0 0.2 3.4e-22 78.8 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS70567.1 - 4.4e-21 74.9 0.2 1.8e-20 72.9 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 RUS70567.1 - 3.4e-20 72.4 0.0 3.3e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 F5/8 type C domain Met_10 PF02475.16 RUS70568.1 - 4.2e-58 196.4 0.1 5.8e-58 195.9 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 RUS70568.1 - 0.014 14.6 0.1 0.021 14.0 0.1 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.7 RUS70568.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_6 PF13405.6 RUS70570.1 - 0.02 14.8 0.2 0.049 13.6 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 RUS70570.1 - 0.022 14.3 0.2 0.052 13.1 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 RUS70570.1 - 0.2 12.2 0.3 0.2 12.2 0.3 2.2 2 1 1 3 3 3 0 EF-hand domain pair TauD PF02668.16 RUS70571.1 - 3.7e-41 141.7 0.0 5.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RUS70571.1 - 1.3e-11 44.9 0.0 3.3e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DapB_N PF01113.20 RUS70571.1 - 0.076 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gal-bind_lectin PF00337.22 RUS70572.1 - 1.8e-28 98.7 0.1 3.5e-28 97.8 0.0 1.5 1 1 0 2 2 2 1 Galactoside-binding lectin Insulin PF00049.18 RUS70573.1 - 2.7e-07 31.5 6.7 6.4e-06 27.1 6.7 2.3 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Lectin_C PF00059.21 RUS70575.1 - 0.13 13.0 0.0 0.22 12.3 0.0 1.4 1 1 0 1 1 1 0 Lectin C-type domain CH PF00307.31 RUS70576.1 - 5.3e-12 45.9 0.0 7.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS70576.1 - 3.6e-06 26.7 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 RUS70576.1 - 0.15 12.3 0.1 0.44 10.8 0.0 1.8 2 1 0 2 2 2 0 CDC24 Calponin DUF3432 PF11914.8 RUS70577.1 - 0.0036 17.5 13.7 0.0078 16.4 13.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3432) DUF3751 PF12571.8 RUS70577.1 - 0.76 9.8 7.0 4.7 7.3 0.6 3.2 1 1 3 4 4 4 0 Phage tail-collar fibre protein Phageshock_PspD PF09584.10 RUS70578.1 - 0.64 10.1 13.7 7.9 6.6 2.9 3.0 1 1 1 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) DUF4023 PF13215.6 RUS70579.1 - 0.0073 16.3 4.5 2.2 8.4 0.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF4023) Pollen_allerg_1 PF01357.21 RUS70579.1 - 0.071 13.1 5.1 2.7 8.1 0.3 2.5 2 0 0 2 2 2 0 Pollen allergen HMG_box PF00505.19 RUS70579.1 - 0.41 11.1 7.8 4.2 7.9 0.8 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box L31 PF09784.9 RUS70579.1 - 0.46 10.9 5.1 11 6.5 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF1492 PF07374.11 RUS70579.1 - 0.95 9.7 2.9 29 4.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Ig_3 PF13927.6 RUS70580.1 - 1.6e-22 79.9 9.2 3.8e-13 49.8 0.0 4.4 5 1 0 5 5 3 3 Immunoglobulin domain I-set PF07679.16 RUS70580.1 - 1.2e-15 57.3 0.3 9.1e-10 38.5 0.0 3.5 4 0 0 4 4 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS70580.1 - 2.3e-15 56.7 0.9 1.4e-10 41.4 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 RUS70580.1 - 6.3e-14 51.9 2.5 2.6e-08 33.9 0.0 4.0 4 1 0 4 4 3 2 Immunoglobulin domain V-set PF07686.17 RUS70580.1 - 7.6e-10 38.9 0.6 0.00042 20.5 0.0 4.2 3 1 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS70580.1 - 3.3e-07 30.3 0.2 0.034 14.2 0.0 3.0 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.6 RUS70580.1 - 4.9e-06 26.5 0.5 1.2e-05 25.2 0.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family Ig_4 PF16680.5 RUS70580.1 - 0.0009 19.5 0.0 0.02 15.1 0.0 2.7 3 0 0 3 3 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS70580.1 - 0.0012 19.2 0.0 0.0074 16.7 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Chordopox_A13L PF05961.11 RUS70580.1 - 0.0025 18.0 0.9 0.0074 16.5 0.9 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein PRIMA1 PF16101.5 RUS70580.1 - 0.0028 17.7 0.3 0.0083 16.2 0.1 1.9 2 0 0 2 2 1 1 Proline-rich membrane anchor 1 DAG1 PF05454.11 RUS70580.1 - 0.0039 16.6 0.1 0.0067 15.8 0.1 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Ninjurin PF04923.12 RUS70580.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Ninjurin EphA2_TM PF14575.6 RUS70580.1 - 0.01 16.7 1.1 0.012 16.5 0.0 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS70580.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 RUS70580.1 - 0.019 14.8 0.1 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF5305 PF17231.2 RUS70580.1 - 0.02 14.3 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Herpes_gE PF02480.16 RUS70580.1 - 0.028 13.2 0.1 0.05 12.3 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 RUS70580.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Rifin G6B PF15096.6 RUS70580.1 - 0.033 14.0 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 G6B family Ig_6 PF18452.1 RUS70580.1 - 0.051 13.2 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain NVEALA PF14055.6 RUS70580.1 - 0.073 13.0 1.5 0.33 11.0 0.2 2.7 2 1 0 2 2 2 0 NVEALA protein TMEM51 PF15345.6 RUS70580.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 C1-set PF07654.15 RUS70580.1 - 0.11 12.9 0.8 3.5 8.1 0.0 3.3 3 1 0 3 3 3 0 Immunoglobulin C1-set domain ECSCR PF15820.5 RUS70580.1 - 0.12 12.2 1.7 0.52 10.2 1.7 2.1 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4834 PF16118.5 RUS70580.1 - 0.14 13.1 0.3 0.6 11.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) SP_C-Propep PF08999.10 RUS70580.1 - 0.15 11.9 2.1 0.19 11.6 0.8 1.8 2 0 0 2 2 1 0 Surfactant protein C, N terminal propeptide Syndecan PF01034.20 RUS70580.1 - 0.18 11.7 0.1 9.6 6.2 0.4 2.4 2 0 0 2 2 2 0 Syndecan domain DUF4307 PF14155.6 RUS70580.1 - 0.32 10.8 5.3 1.1 9.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) HSP70 PF00012.20 RUS70581.1 - 3.3e-84 283.2 34.5 3.3e-84 283.2 34.5 3.6 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 RUS70581.1 - 0.00064 18.6 2.7 0.0017 17.2 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein HetR_C PF18460.1 RUS70581.1 - 0.12 12.3 1.5 5.7 6.9 0.0 3.4 2 1 1 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain DUF1657 PF07870.11 RUS70581.1 - 0.26 11.2 6.4 0.032 14.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Prominin PF05478.11 RUS70581.1 - 0.34 8.8 9.2 0.77 7.6 9.2 1.5 1 0 0 1 1 1 0 Prominin Cbl_N PF02262.16 RUS70582.1 - 4.8e-52 175.2 0.3 6.9e-52 174.7 0.3 1.2 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 RUS70582.1 - 6.8e-44 147.6 0.1 2.2e-43 146.0 0.0 1.9 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 RUS70582.1 - 2.5e-39 133.9 0.3 7.3e-39 132.4 0.3 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain EF-hand_12 PF17901.1 RUS70582.1 - 0.041 14.3 0.1 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand fold domain Retrotrans_gag PF03732.17 RUS70582.1 - 0.19 12.0 1.1 1.4 9.2 0.1 2.7 3 0 0 3 3 3 0 Retrotransposon gag protein Tctex-1 PF03645.13 RUS70583.1 - 1.2e-16 60.8 0.1 1.7e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Tctex-1 family BRCT PF00533.26 RUS70584.1 - 5.3e-61 203.0 2.9 1.8e-13 50.7 0.0 7.7 7 0 0 7 7 7 7 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RUS70584.1 - 3.2e-53 177.5 14.8 1.5e-18 66.5 0.3 7.1 7 0 0 7 7 7 5 twin BRCT domain BRCT_2 PF16589.5 RUS70584.1 - 9.5e-27 93.2 6.5 0.0079 16.6 0.0 7.7 7 0 0 7 7 7 7 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RUS70584.1 - 2.2e-13 49.9 0.0 8.1e-05 22.4 0.0 5.9 6 1 1 7 7 7 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RUS70584.1 - 3.3e-10 40.1 0.5 0.004 17.4 0.0 5.6 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 RUS70584.1 - 1e-06 28.7 0.1 0.08 13.0 0.0 5.3 5 0 0 5 5 5 1 BRCA1 C Terminus (BRCT) domain SMC_N PF02463.19 RUS70585.1 - 8.1e-12 45.0 4.5 8.1e-12 45.0 4.5 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RUS70585.1 - 7.1e-08 32.6 44.0 5.4e-05 23.1 25.9 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RUS70585.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 RUS70585.1 - 0.0033 17.0 0.4 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RUS70585.1 - 0.0078 16.7 103.6 0.0079 16.7 55.5 6.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 RUS70585.1 - 0.0084 16.0 0.0 0.0084 16.0 0.0 3.5 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF948 PF06103.11 RUS70585.1 - 1.6 9.0 26.5 3.1 8.1 0.1 5.8 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) SecD-TM1 PF13721.6 RUS70585.1 - 2.8 8.4 10.0 0.5 10.9 1.7 3.4 2 1 1 3 3 3 0 SecD export protein N-terminal TM region 7tm_1 PF00001.21 RUS70586.1 - 1.2e-25 90.3 2.9 1.5e-25 90.0 2.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS70586.1 - 3.1e-06 26.7 7.3 5.9e-06 25.8 7.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Marek_A PF02124.15 RUS70586.1 - 0.076 12.8 0.0 0.29 11.0 0.0 1.8 1 1 1 2 2 2 0 Marek's disease glycoprotein A COX6C PF02937.15 RUS70586.1 - 0.29 11.3 4.6 0.52 10.5 0.0 3.1 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc ATP-gua_Ptrans PF00217.19 RUS70587.1 - 5.5e-81 271.1 0.0 7.8e-81 270.6 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RUS70587.1 - 4.3e-23 81.5 0.0 8.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF4512 PF14975.6 RUS70587.1 - 5.4 7.9 5.0 46 4.9 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) EAP30 PF04157.16 RUS70588.1 - 9.1e-75 251.0 0.2 1e-74 250.8 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MULE PF10551.9 RUS70590.1 - 3.9e-26 91.3 1.0 1.1e-17 64.2 0.0 3.3 3 0 0 3 3 3 2 MULE transposase domain DUF5575 PF17738.1 RUS70590.1 - 1.6e-09 37.3 0.2 3.6e-09 36.1 0.2 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5575) SWIM PF04434.17 RUS70590.1 - 0.0033 17.1 0.0 0.0091 15.6 0.0 1.7 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.15 RUS70590.1 - 0.011 16.4 0.9 0.034 14.8 0.9 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain ESCRT-II PF05871.12 RUS70590.1 - 0.071 13.4 0.9 34 4.7 0.3 3.7 4 0 0 4 4 4 0 ESCRT-II complex subunit Bactofilin PF04519.13 RUS70590.1 - 0.24 11.7 4.9 0.43 10.9 2.8 2.3 2 1 0 2 2 2 0 Polymer-forming cytoskeletal DUF3283 PF11686.8 RUS70590.1 - 0.46 10.4 2.7 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Gp-FAR-1 PF05823.12 RUS70590.1 - 2.1 8.7 5.9 1.3 9.3 0.7 3.1 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) 7tm_1 PF00001.21 RUS70591.1 - 4.9e-13 49.0 4.5 4.9e-13 49.0 4.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) NGP1NT PF08153.12 RUS70592.1 - 0.034 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 NGP1NT (NUC091) domain COG4 PF08318.12 RUS70593.1 - 5.8e-66 222.9 4.1 6e-36 124.2 2.2 2.4 2 0 0 2 2 2 2 COG4 transport protein FAM110_C PF14160.6 RUS70593.1 - 0.0041 18.2 2.8 0.039 15.0 0.8 2.6 2 0 0 2 2 2 1 Centrosome-associated C terminus DUF2982 PF11201.8 RUS70593.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) RNase_H PF00075.24 RUS70594.1 - 1.8e-12 47.6 2.4 4.9e-12 46.2 0.2 2.4 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS70594.1 - 0.00011 22.0 0.1 0.00026 20.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like DUF4864 PF16156.5 RUS70594.1 - 0.07 13.8 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Metallophos PF00149.28 RUS70595.1 - 2e-14 54.6 1.5 3e-14 54.0 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS70595.1 - 7.3e-06 26.3 0.3 0.00022 21.4 0.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Pribosyltran PF00156.27 RUS70596.1 - 7.8e-23 80.7 0.0 9.2e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RUS70596.1 - 7.6e-06 25.5 0.0 9.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Mito_carr PF00153.27 RUS70597.1 - 1.3e-48 162.8 5.6 1.5e-19 69.7 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Transglut_N PF00868.20 RUS70598.1 - 2.3e-26 92.5 0.0 2.9e-25 88.9 0.0 2.5 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 RUS70598.1 - 2.6e-19 69.3 0.1 4.2e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 RUS70598.1 - 3e-15 56.6 1.5 4.8e-15 56.0 0.4 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF4232 PF14016.6 RUS70598.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) ASC PF00858.24 RUS70599.1 - 1.9e-74 251.3 6.7 2.3e-74 251.0 6.7 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ABC_tran PF00005.27 RUS70601.1 - 6.4e-16 59.1 0.0 1.4e-15 58.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS70601.1 - 5.7e-08 32.9 1.7 0.00025 21.0 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RUS70601.1 - 0.0014 19.2 0.5 0.0022 18.5 0.5 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RUS70601.1 - 0.0045 16.7 0.2 0.0087 15.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS70601.1 - 0.017 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 RUS70601.1 - 0.018 13.9 0.1 0.027 13.3 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 RUS70601.1 - 0.027 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 RUS70601.1 - 0.031 14.0 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RUS70601.1 - 0.077 12.4 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 RUS70601.1 - 0.098 12.4 0.1 8.8 6.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 RUS70601.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 RUS70601.1 - 0.22 11.3 0.3 0.43 10.4 0.3 1.4 1 0 0 1 1 1 0 MukB N-terminal ABC_tran PF00005.27 RUS70602.1 - 2.8e-36 125.1 0.2 5.9e-25 88.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS70602.1 - 2.1e-16 60.6 0.6 4.5e-08 33.3 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RUS70602.1 - 5.2e-14 52.1 24.8 8.7e-14 51.4 24.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein SbcCD_C PF13558.6 RUS70602.1 - 0.00034 20.8 0.2 0.43 10.8 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 RUS70602.1 - 0.00096 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SMC_N PF02463.19 RUS70602.1 - 0.0042 16.5 0.9 0.67 9.3 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS70602.1 - 0.11 12.9 0.5 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RUS70602.1 - 0.12 11.3 0.2 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 RUS70602.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FYVE PF01363.21 RUS70603.1 - 3.1e-12 46.4 4.8 4e-12 46.1 4.8 1.2 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 RUS70603.1 - 0.0014 18.8 5.2 0.0023 18.1 5.2 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 RUS70603.1 - 0.015 15.4 9.8 0.022 14.9 9.8 1.2 1 0 0 1 1 1 0 AN1-like Zinc finger DUF4429 PF14472.6 RUS70603.1 - 0.22 12.2 0.1 1.1 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4429) RVT_1 PF00078.27 RUS70604.1 - 2.4e-12 46.9 0.0 4.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tom22 PF04281.13 RUS70604.1 - 0.0087 15.9 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom22 DUF4707 PF15806.5 RUS70605.1 - 6.1e-28 97.9 0.6 8.4e-28 97.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4707) RL11D PF11088.8 RUS70605.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Macoilin PF09726.9 RUS70605.1 - 0.31 9.5 4.2 0.34 9.4 4.2 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 RUS70605.1 - 2.6 7.6 16.3 4.4 6.8 16.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 RUS70606.1 - 4.9e-05 22.9 21.8 6.5e-05 22.5 21.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS70606.1 - 9.1e-05 20.9 20.0 0.00011 20.6 20.0 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 RUS70606.1 - 0.00059 19.9 8.5 0.0007 19.7 8.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RPN2_C PF18004.1 RUS70606.1 - 0.00063 19.7 15.5 0.0011 18.9 15.5 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2052 PF09747.9 RUS70606.1 - 0.0043 17.2 21.4 0.0073 16.5 21.4 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.13 RUS70606.1 - 0.0043 17.0 16.1 0.0071 16.2 16.1 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Tim54 PF11711.8 RUS70606.1 - 0.0065 15.3 14.9 0.0065 15.3 14.9 1.5 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 RUS70606.1 - 0.0081 15.5 19.1 0.011 15.1 19.1 1.2 1 0 0 1 1 1 1 BUD22 DUF4820 PF16091.5 RUS70606.1 - 0.0084 15.5 8.2 0.013 14.9 8.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 RUS70606.1 - 0.0085 16.3 9.6 0.014 15.5 9.6 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.6 RUS70606.1 - 0.009 16.5 5.7 0.012 16.2 5.7 1.3 1 0 0 1 1 1 1 AAA domain SpoIIIAH PF12685.7 RUS70606.1 - 0.0092 15.8 9.2 0.013 15.4 9.2 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein RR_TM4-6 PF06459.12 RUS70606.1 - 0.011 15.6 15.1 0.014 15.2 15.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 RUS70606.1 - 0.024 14.3 21.2 0.033 13.8 21.2 1.2 1 0 0 1 1 1 0 PPP4R2 Ccdc124 PF06244.12 RUS70606.1 - 0.031 14.8 14.6 13 6.4 13.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 NOA36 PF06524.12 RUS70606.1 - 0.036 13.4 17.4 0.068 12.5 17.4 1.5 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 RUS70606.1 - 0.042 12.6 4.3 0.045 12.5 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM31_MDM32 PF08118.11 RUS70606.1 - 0.048 12.3 3.7 0.081 11.6 3.7 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins V_ATPase_I PF01496.19 RUS70606.1 - 0.054 11.4 9.5 0.067 11.1 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 RUS70606.1 - 0.071 13.4 11.4 0.12 12.7 11.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5523 PF17661.1 RUS70606.1 - 0.079 12.6 24.1 0.12 12.1 24.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) ORC_WH_C PF18137.1 RUS70606.1 - 0.089 12.9 9.8 0.14 12.2 9.8 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Mpp10 PF04006.12 RUS70606.1 - 0.16 10.4 28.3 0.22 9.9 28.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 RUS70606.1 - 0.17 11.6 18.0 0.29 10.9 18.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RAB3GAP2_C PF14656.6 RUS70606.1 - 0.21 9.8 5.1 0.29 9.3 5.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CobT PF06213.12 RUS70606.1 - 0.22 10.9 27.1 0.31 10.4 27.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 RUS70606.1 - 0.24 11.8 8.1 0.38 11.2 8.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 RUS70606.1 - 0.28 11.5 25.6 0.5 10.6 25.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SID-1_RNA_chan PF13965.6 RUS70606.1 - 0.31 9.4 1.3 0.3 9.5 1.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MID_MedPIWI PF18296.1 RUS70606.1 - 0.34 10.7 1.9 0.48 10.2 1.9 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF913 PF06025.12 RUS70606.1 - 0.34 9.8 9.2 0.46 9.4 9.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5308 PF17233.2 RUS70606.1 - 0.34 11.1 3.0 0.51 10.6 3.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SpoIIP PF07454.11 RUS70606.1 - 0.35 10.3 12.6 0.5 9.8 12.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DNA_pol_phi PF04931.13 RUS70606.1 - 0.37 8.8 35.8 0.54 8.3 35.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 RUS70606.1 - 0.39 9.8 16.4 0.54 9.3 16.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Presenilin PF01080.17 RUS70606.1 - 0.46 9.2 11.7 0.59 8.8 11.7 1.1 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 RUS70606.1 - 0.51 9.7 3.5 0.78 9.1 3.5 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NPR3 PF03666.13 RUS70606.1 - 0.51 9.1 8.9 0.8 8.4 8.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EIIBC-GUT_N PF03612.14 RUS70606.1 - 0.56 9.9 5.5 0.86 9.3 5.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PIP5K PF01504.18 RUS70606.1 - 0.63 9.2 4.1 1.1 8.5 4.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Afi1 PF07792.12 RUS70606.1 - 0.64 10.5 11.3 1.1 9.8 11.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_polI_A34 PF08208.11 RUS70606.1 - 0.68 10.0 20.2 1.1 9.4 20.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Paf1 PF03985.13 RUS70606.1 - 0.72 8.8 30.3 1.1 8.2 30.3 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 RUS70606.1 - 0.78 8.0 21.8 1.1 7.5 21.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.11 RUS70606.1 - 0.81 9.0 7.6 1.1 8.6 7.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Membralin PF09746.9 RUS70606.1 - 0.9 8.5 5.0 1.4 7.9 5.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF3306 PF11748.8 RUS70606.1 - 0.92 10.4 13.1 1.8 9.5 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SLC12 PF03522.15 RUS70606.1 - 0.98 8.4 4.0 1.2 8.0 4.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Prothymosin PF03247.14 RUS70606.1 - 1.1 9.8 46.2 2.1 8.9 46.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Merozoite_SPAM PF07133.11 RUS70606.1 - 1.3 9.0 48.1 1.9 8.5 48.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LAP1C PF05609.12 RUS70606.1 - 1.3 8.0 11.3 1.8 7.6 11.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3438 PF11920.8 RUS70606.1 - 1.5 8.0 4.7 2.3 7.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) FYDLN_acid PF09538.10 RUS70606.1 - 1.6 9.5 21.5 3.1 8.5 21.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MCM_bind PF09739.9 RUS70606.1 - 2.3 6.6 9.1 3 6.2 9.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Serinc PF03348.15 RUS70606.1 - 2.6 6.9 5.9 3.6 6.4 5.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 RUS70606.1 - 2.8 6.7 4.6 4.6 6.0 4.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 RUS70606.1 - 3.1 6.6 7.1 4.3 6.1 7.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Eapp_C PF10238.9 RUS70606.1 - 4 7.5 10.4 8 6.5 10.4 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Usp PF00582.26 RUS70606.1 - 4.1 7.9 17.1 17 5.9 16.1 2.2 2 0 0 2 2 2 0 Universal stress protein family Nop53 PF07767.11 RUS70606.1 - 4.9 6.4 30.9 7.2 5.9 30.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HSP70 PF00012.20 RUS70606.1 - 5.3 5.1 11.6 7 4.7 11.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Hid1 PF12722.7 RUS70606.1 - 5.5 5.0 7.7 6.9 4.7 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.9 RUS70606.1 - 6.4 5.2 10.2 8.6 4.8 10.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator AIF_C PF14721.6 RUS70606.1 - 6.9 7.0 9.9 13 6.2 9.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDK2AP PF09806.9 RUS70606.1 - 7.1 6.6 8.7 0.42 10.6 2.2 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF740 PF05340.12 RUS70606.1 - 8 5.1 15.9 11 4.6 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Zip PF02535.22 RUS70606.1 - 9.7 5.3 9.7 14 4.8 9.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.8 RUS70606.1 - 10 5.9 9.7 18 5.1 9.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MTHFR_C PF12225.8 RUS70607.1 - 0.0034 17.0 1.2 0.0034 17.0 1.2 1.8 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal Trm112p PF03966.16 RUS70607.1 - 0.48 11.0 1.9 18 6.0 0.6 2.9 2 1 0 2 2 2 0 Trm112p-like protein Smr PF01713.21 RUS70608.1 - 4.9e-06 26.8 0.0 9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Smr domain MCM_bind PF09739.9 RUS70608.1 - 4.5 5.6 8.2 5.5 5.3 8.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Plasmodium_HRP PF05403.11 RUS70609.1 - 0.82 9.4 83.8 0.008 16.0 67.9 4.0 2 1 0 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) Thioredoxin_10 PF17991.1 RUS70609.1 - 2.9 8.5 9.2 5.5 7.5 8.2 2.0 1 1 0 1 1 1 0 Thioredoxin like C-terminal domain AA_permease PF00324.21 RUS70610.1 - 4.6e-18 65.1 26.3 5.6e-18 64.8 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease RVT_1 PF00078.27 RUS70611.1 - 0.0035 16.9 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_64 PF09258.10 RUS70612.1 - 4.9e-85 284.7 0.1 6.6e-85 284.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RUS70612.1 - 5.9e-48 163.6 0.1 1.4e-47 162.4 0.0 1.6 2 0 0 2 2 2 1 Exostosin family NUDIX PF00293.28 RUS70613.1 - 4.3e-06 26.8 0.1 0.27 11.3 0.0 3.5 3 0 0 3 3 3 3 NUDIX domain C1q PF00386.21 RUS70614.1 - 1.8e-14 54.0 0.0 4.3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 RUS70614.1 - 0.11 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 BclA C-terminal domain TAP42 PF04177.12 RUS70615.1 - 9.6e-81 271.4 12.3 1.1e-80 271.1 12.3 1.0 1 0 0 1 1 1 1 TAP42-like family PNP_UDP_1 PF01048.20 RUS70616.1 - 3.7e-21 75.4 0.1 4.4e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF745 PF05335.13 RUS70617.1 - 0.031 14.0 10.6 0.27 11.0 2.3 3.6 1 1 4 5 5 5 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 RUS70617.1 - 0.21 11.6 8.1 8.7 6.4 0.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 RUS70617.1 - 1.2 8.9 18.1 5.3 6.8 2.7 3.6 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3540 PF12059.8 RUS70617.1 - 9 6.1 11.6 5.1 6.9 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3540) Abhydrolase_9_N PF15420.6 RUS70618.1 - 6.1 6.8 18.8 1.8 8.6 9.1 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Zip PF02535.22 RUS70619.1 - 1.3e-50 172.5 15.2 1.6e-50 172.2 15.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.12 RUS70619.1 - 7.5 6.5 7.4 0.73 9.8 2.2 2.0 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Ets PF00178.22 RUS70620.1 - 3.9e-36 123.4 0.3 6.3e-36 122.7 0.3 1.3 1 0 0 1 1 1 1 Ets-domain ANF_receptor PF01094.28 RUS70621.1 - 2.5e-48 165.0 0.1 7.3e-48 163.5 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS70621.1 - 6e-12 45.9 0.0 5e-06 26.4 0.0 2.5 3 0 0 3 3 3 2 Periplasmic binding protein OpuAC PF04069.12 RUS70621.1 - 0.042 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DUF948 PF06103.11 RUS70621.1 - 0.065 13.5 0.9 0.22 11.8 0.9 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LapA_dom PF06305.11 RUS70621.1 - 0.1 12.4 0.5 0.28 11.0 0.5 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Isochorismatase PF00857.20 RUS70622.1 - 4.8e-28 98.5 1.7 8.9e-28 97.6 1.7 1.4 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.32 RUS70623.1 - 7.1e-62 203.9 14.5 7.9e-10 39.2 0.5 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS70623.1 - 1.5e-14 54.0 1.1 0.011 16.0 0.0 5.4 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS70623.1 - 1.8e-09 36.8 10.3 0.16 10.6 0.0 6.2 1 1 5 6 6 6 5 Nucleoporin Nup120/160 LisH PF08513.11 RUS70623.1 - 1e-05 25.3 0.3 2.1e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 RUS70623.1 - 4.3e-05 22.5 0.1 0.24 10.1 0.0 3.6 1 1 2 4 4 4 2 Nup133 N terminal like Pox_A_type_inc PF04508.12 RUS70623.1 - 0.0089 15.8 0.2 0.022 14.6 0.2 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat C1q PF00386.21 RUS70624.1 - 1.8e-09 37.9 0.0 5.3e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 C1q domain ATG16 PF08614.11 RUS70624.1 - 0.0036 17.5 6.5 0.057 13.6 4.8 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) V-set PF07686.17 RUS70624.1 - 0.0055 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain GAS PF13851.6 RUS70624.1 - 0.012 14.9 0.3 0.028 13.8 0.3 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 RUS70624.1 - 0.012 14.5 1.0 0.021 13.7 1.0 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 RUS70624.1 - 0.015 15.7 0.6 0.023 15.1 0.6 1.2 1 0 0 1 1 1 0 Fez1 COG2 PF06148.11 RUS70624.1 - 0.021 14.9 0.4 3.5 7.7 0.1 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nsp1_C PF05064.13 RUS70624.1 - 0.039 13.8 3.3 0.065 13.0 0.9 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.7 RUS70624.1 - 0.052 13.7 0.3 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Tropomyosin like Ig_3 PF13927.6 RUS70624.1 - 0.053 14.1 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain PA14 PF07691.12 RUS70624.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 PA14 domain Tropomyosin PF00261.20 RUS70624.1 - 0.061 12.7 1.7 0.069 12.5 0.4 1.6 2 0 0 2 2 2 0 Tropomyosin I-set PF07679.16 RUS70624.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Laminin_II PF06009.12 RUS70624.1 - 0.1 12.6 6.4 0.1 12.6 3.9 2.2 1 1 0 2 2 2 0 Laminin Domain II DegS PF05384.11 RUS70624.1 - 0.11 11.9 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Sensor protein DegS CENP-H PF05837.12 RUS70624.1 - 0.12 12.8 8.0 0.21 12.0 4.1 2.4 1 1 0 2 2 2 0 Centromere protein H (CENP-H) MscS_porin PF12795.7 RUS70624.1 - 0.13 11.8 7.3 0.24 10.9 7.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain M PF02370.16 RUS70624.1 - 0.18 12.5 2.1 0.51 11.1 2.1 1.8 1 0 0 1 1 1 0 M protein repeat DUF3450 PF11932.8 RUS70624.1 - 0.18 11.0 2.1 0.31 10.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 RUS70624.1 - 0.21 10.5 2.6 0.32 9.9 2.2 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4472 PF14739.6 RUS70624.1 - 0.23 12.2 1.6 8.5 7.2 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) AATF-Che1 PF13339.6 RUS70624.1 - 0.32 11.7 2.3 0.56 10.9 2.3 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF240 PF03086.14 RUS70624.1 - 0.73 9.8 5.6 1.5 8.8 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF240) SlyX PF04102.12 RUS70624.1 - 0.87 10.2 2.8 2.8 8.6 0.0 2.9 2 1 1 3 3 3 0 SlyX SKA1 PF07160.12 RUS70624.1 - 1.4 8.8 4.4 5.7 6.7 2.2 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 PPC PF04151.15 RUS70624.1 - 6.7 7.9 7.1 0.81 10.8 0.2 3.0 3 2 0 3 3 2 0 Bacterial pre-peptidase C-terminal domain HIP1_clath_bdg PF16515.5 RUS70624.1 - 8 7.1 7.6 4.3 8.0 2.3 2.7 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PLA2_B PF01735.18 RUS70626.1 - 9.9e-71 238.6 0.0 1.3e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain 7tm_1 PF00001.21 RUS70629.1 - 1e-15 57.8 7.1 1.5e-15 57.2 7.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS70629.1 - 6.7e-08 32.2 7.6 6.7e-08 32.2 7.6 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS70629.1 - 5e-07 29.6 1.8 5e-07 29.6 1.8 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CreD PF06123.12 RUS70629.1 - 0.0019 17.1 2.6 0.003 16.4 2.6 1.2 1 0 0 1 1 1 1 Inner membrane protein CreD 7TM_GPCR_Srsx PF10320.9 RUS70629.1 - 0.082 12.3 13.5 1.7 8.0 13.5 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx SecG PF03840.14 RUS70629.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.3 4 0 0 4 4 4 0 Preprotein translocase SecG subunit K_channel_TID PF07941.11 RUS70629.1 - 0.83 10.2 3.3 1.4 9.4 3.3 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CIAPIN1 PF05093.13 RUS70631.1 - 9.4e-23 80.6 14.5 1.7e-18 67.0 3.1 2.6 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RGS12_usC PF16612.5 RUS70631.1 - 0.00017 22.0 0.1 0.00041 20.8 0.1 1.7 1 1 0 1 1 1 1 C-terminal unstructured region of RGS12 DDE_5 PF13546.6 RUS70632.1 - 0.018 14.4 0.2 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease XPC-binding PF09280.11 RUS70632.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain TraI_2_C PF07515.11 RUS70632.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Ldl_recept_a PF00057.18 RUS70633.1 - 1.6e-07 31.4 3.3 4.6e-07 29.9 3.3 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.6 RUS70633.1 - 0.003 17.5 0.0 0.003 17.5 0.0 3.2 3 0 0 3 3 3 1 TMEM154 protein family MpPF26 PF07666.11 RUS70633.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 Orf78 PF06024.12 RUS70633.1 - 0.05 13.9 1.1 0.43 10.9 0.0 3.1 2 0 0 2 2 2 0 Orf78 (ac78) LRRC37AB_C PF14914.6 RUS70633.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain SKG6 PF08693.10 RUS70633.1 - 0.64 9.5 5.0 1.3 8.5 5.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kinesin PF00225.23 RUS70634.1 - 1.6e-111 372.5 0.5 1.6e-111 372.5 0.5 2.3 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RUS70634.1 - 1.3e-21 77.1 0.0 3.9e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DUF3914 PF13053.6 RUS70634.1 - 0.064 13.6 2.9 0.14 12.5 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3914) HNH_3 PF13392.6 RUS70635.1 - 1.5e-08 34.2 2.5 2.6e-08 33.5 2.5 1.3 1 0 0 1 1 1 1 HNH endonuclease RVT_1 PF00078.27 RUS70636.1 - 4.8e-24 85.1 0.0 8.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RUS70636.1 - 9.8e-06 25.5 0.2 2.1e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 RUS70636.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Nse4-Nse3_bdg PF15412.6 RUS70638.1 - 0.0029 17.7 0.0 13 6.0 0.0 3.7 1 1 2 3 3 3 2 Binding domain of Nse4/EID3 to Nse3-MAGE Gemini_AL1_M PF08283.11 RUS70638.1 - 0.0051 16.9 2.6 0.011 15.8 1.6 1.8 1 1 1 2 2 2 1 Geminivirus rep protein central domain DUF4822 PF16103.5 RUS70638.1 - 0.036 14.3 0.8 0.21 11.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4822) DUF3952 PF13130.6 RUS70638.1 - 0.045 13.9 1.7 1.2 9.4 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3952) Stap_Strp_tox_C PF02876.17 RUS70638.1 - 0.086 13.2 3.6 7.4 6.9 0.2 3.0 1 1 3 4 4 4 0 Staphylococcal/Streptococcal toxin, beta-grasp domain RnlB_antitoxin PF15933.5 RUS70638.1 - 0.54 10.6 6.5 12 6.3 0.7 3.0 2 2 1 3 3 3 0 Antitoxin to bacterial toxin RNase LS or RnlA Plasmo_rep PF12135.8 RUS70638.1 - 3.9 7.1 12.8 21 4.8 0.3 3.9 4 0 0 4 4 4 0 Plasmodium repeat family DUF2012 PF09430.10 RUS70639.1 - 0.06 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF2294 PF10057.9 RUS70640.1 - 0.021 14.9 4.3 6.8 6.9 0.3 4.3 2 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2294) DUF2267 PF10025.9 RUS70640.1 - 0.59 10.4 2.4 4.4 7.6 2.5 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) Sigma70_r4_2 PF08281.12 RUS70642.1 - 0.023 14.4 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Claudin_2 PF13903.6 RUS70644.1 - 2.5e-13 50.2 10.6 2.6e-12 46.9 10.6 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS70644.1 - 3.6e-06 26.9 4.2 5e-06 26.5 4.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF3040 PF11239.8 RUS70644.1 - 0.031 14.5 2.5 0.031 14.5 2.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Herpes_LMP1 PF05297.11 RUS70645.1 - 0.43 9.7 2.0 0.46 9.6 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4191 PF13829.6 RUS70645.1 - 0.48 9.7 2.0 0.48 9.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 RUS70645.1 - 0.98 8.1 3.4 1.1 7.9 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EMP24_GP25L PF01105.24 RUS70645.1 - 1.6 8.6 10.5 0.44 10.5 7.4 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PrgI PF12666.7 RUS70645.1 - 3.2 8.5 7.9 3.3 8.5 7.1 1.4 1 1 0 1 1 1 0 PrgI family protein DUF2254 PF10011.9 RUS70645.1 - 6.2 5.5 6.1 8.1 5.2 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) THEG PF14912.6 RUS70646.1 - 3e-46 155.7 20.9 1e-14 54.7 0.8 5.6 2 2 4 6 6 6 6 Testicular haploid expressed repeat PDEase_I_N PF08499.12 RUS70647.1 - 0.0096 15.7 3.3 6.9 6.6 0.0 4.4 4 1 1 5 5 5 2 3'5'-cyclic nucleotide phosphodiesterase N-terminal UvsY PF11056.8 RUS70647.1 - 0.074 13.4 0.5 0.074 13.4 0.5 2.8 4 0 0 4 4 4 0 Recombination, repair and ssDNA binding protein UvsY Fanconi_A_N PF15865.5 RUS70648.1 - 5.5e-29 101.6 7.9 7.1e-29 101.3 7.9 1.2 1 0 0 1 1 1 1 Fanconi anaemia group A protein N terminus XK-related PF09815.9 RUS70649.1 - 0.18 10.9 1.2 0.28 10.2 1.2 1.3 1 0 0 1 1 1 0 XK-related protein YkyA PF10368.9 RUS70649.1 - 3.3 7.4 6.9 0.19 11.4 1.5 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Metallophos PF00149.28 RUS70652.1 - 2.3e-17 64.2 0.2 4.2e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS70652.1 - 5.9e-07 29.8 0.0 1.5e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PsbN PF02468.15 RUS70652.1 - 0.17 11.8 0.6 0.61 10.0 0.6 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Sulfotransfer_1 PF00685.27 RUS70653.1 - 1.7e-17 63.8 0.1 2e-17 63.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain TRAM_LAG1_CLN8 PF03798.16 RUS70655.1 - 4.8e-09 36.2 15.5 4.8e-09 36.2 15.5 1.6 1 1 1 2 2 2 1 TLC domain Botulinum_HA-17 PF05588.11 RUS70655.1 - 0.007 16.5 0.7 0.011 15.8 0.7 1.3 1 0 0 1 1 1 1 Clostridium botulinum HA-17 domain Dpy-30 PF05186.13 RUS70656.1 - 6.6e-06 25.7 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif Ank_2 PF12796.7 RUS70657.1 - 7.5e-19 68.1 0.4 7e-08 33.0 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS70657.1 - 1.4e-15 57.4 5.2 3.4e-08 33.9 0.2 5.2 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS70657.1 - 1.9e-15 56.5 2.0 6.7e-05 23.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 RUS70657.1 - 3.2e-13 48.5 0.4 0.00052 20.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS70657.1 - 1.2e-12 47.8 2.2 1.9e-06 28.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) PX PF00787.24 RUS70659.1 - 2.4e-17 62.9 0.9 5.2e-17 61.9 0.9 1.6 1 0 0 1 1 1 1 PX domain LRR_8 PF13855.6 RUS70659.1 - 6.7e-13 48.2 18.0 2e-06 27.5 6.2 3.6 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RUS70659.1 - 2e-09 37.5 21.6 1.9e-06 28.1 5.2 5.0 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS70659.1 - 5.7e-09 35.7 1.6 1.9e-08 34.0 1.7 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 RUS70659.1 - 0.0033 17.4 20.8 0.23 11.6 0.4 6.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 RUS70659.1 - 0.0047 17.3 19.5 3.4 8.6 0.7 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat zf-CCHC PF00098.23 RUS70660.1 - 1.2e-55 183.2 78.8 1.6e-07 31.1 2.9 8.2 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_3 PF13917.6 RUS70660.1 - 6.4e-12 45.2 45.7 0.024 14.6 0.1 8.0 2 1 6 8 8 8 8 Zinc knuckle zf-CCHC_4 PF14392.6 RUS70660.1 - 8.3e-12 44.7 47.2 0.088 12.6 0.4 8.1 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_5 PF14787.6 RUS70660.1 - 4.1e-09 36.0 57.5 0.0093 15.7 1.4 8.1 6 2 2 8 8 8 7 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 RUS70660.1 - 0.0023 17.7 5.2 0.016 15.0 0.8 8.1 8 0 0 8 8 8 5 Zinc knuckle zf-CCHC_6 PF15288.6 RUS70660.1 - 0.012 15.4 2.5 0.012 15.4 2.5 7.8 6 2 2 8 8 8 0 Zinc knuckle DUF753 PF05444.12 RUS70660.1 - 4.8 7.2 40.8 14 5.7 9.6 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF753) Pex26 PF07163.12 RUS70661.1 - 2.2e-32 112.6 0.9 2.8e-32 112.2 0.9 1.1 1 0 0 1 1 1 1 Pex26 protein UPF0242 PF06785.11 RUS70662.1 - 0.018 15.1 5.5 0.034 14.2 5.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pex19 PF04614.12 RUS70662.1 - 0.023 14.5 2.8 0.037 13.8 2.8 1.3 1 0 0 1 1 1 0 Pex19 protein family MLD PF11647.8 RUS70662.1 - 0.063 13.6 0.6 0.41 11.0 0.9 2.1 2 0 0 2 2 2 0 Membrane Localization Domain 7tm_3 PF00003.22 RUS70663.1 - 1.2e-54 185.5 15.3 1.8e-54 185.0 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 RUS70663.1 - 1e-12 47.8 10.3 3.6e-12 46.1 10.3 2.0 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR ANF_receptor PF01094.28 RUS70663.1 - 2e-09 37.1 0.0 3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Ras PF00071.22 RUS70664.1 - 1.1e-56 190.9 0.1 1.4e-56 190.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70664.1 - 3.9e-36 123.9 0.1 6.6e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS70664.1 - 1e-15 57.7 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS70664.1 - 0.00014 21.8 0.1 0.031 14.2 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RUS70664.1 - 0.00092 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS70664.1 - 0.0011 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS70664.1 - 0.0029 17.2 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RUS70664.1 - 0.0062 16.3 0.1 0.5 10.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GCFC PF07842.12 RUS70665.1 - 4.4e-88 295.5 7.6 8.1e-88 294.6 7.6 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 RUS70665.1 - 7.9e-20 71.2 4.9 7.9e-20 71.2 4.9 2.3 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 RUS70665.1 - 7.3e-15 54.6 3.0 1.4e-14 53.7 3.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RUS70665.1 - 0.0036 17.3 0.5 0.01 15.9 0.5 1.8 1 0 0 1 1 1 1 G-patch domain DNA_gyraseA_C PF03989.13 RUS70665.1 - 0.033 13.7 0.1 0.074 12.5 0.1 1.6 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller TUDOR_5 PF18359.1 RUS70666.1 - 0.59 9.9 5.9 7.1 6.4 0.1 4.0 4 1 0 4 4 4 0 Histone methyltransferase Tudor domain 1 7tm_1 PF00001.21 RUS70667.1 - 1.1e-67 228.1 18.7 1.4e-40 139.3 9.0 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70667.1 - 0.00058 19.6 10.1 0.00058 19.6 10.1 2.3 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Annexin PF00191.20 RUS70669.1 - 3.1e-195 632.6 33.5 7.6e-29 99.6 0.2 8.6 9 0 0 9 9 9 8 Annexin Fn3_assoc PF13287.6 RUS70669.1 - 1.9e-12 47.1 0.0 4.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.6 RUS70669.1 - 1.8e-11 43.9 0.0 4.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Sigma70_ner PF04546.13 RUS70669.1 - 0.00085 19.3 1.2 0.00085 19.3 1.2 3.0 3 0 0 3 3 3 2 Sigma-70, non-essential region Myb_DNA-bind_7 PF15963.5 RUS70669.1 - 0.0029 17.4 6.3 5.2 7.0 0.0 5.8 6 0 0 6 6 6 1 Myb DNA-binding like RPAP3_C PF13877.6 RUS70669.1 - 0.067 13.7 0.1 4.7 7.8 0.0 3.4 3 0 0 3 3 2 0 Potential Monad-binding region of RPAP3 DUF3574 PF12098.8 RUS70669.1 - 0.09 12.6 1.0 24 4.8 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3574) FeoB_Cyto PF17910.1 RUS70669.1 - 0.8 10.3 11.1 3 8.5 0.0 5.8 7 0 0 7 7 7 0 FeoB cytosolic helical domain DUF5101 PF17031.5 RUS70669.1 - 0.89 9.7 5.1 19 5.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) Macoilin PF09726.9 RUS70669.1 - 3.6 6.0 16.3 7.3 5.0 16.3 1.4 1 0 0 1 1 1 0 Macoilin family POX PF07526.11 RUS70669.1 - 4.9 7.7 10.9 43 4.7 6.8 2.7 2 0 0 2 2 2 0 Associated with HOX SSP160 PF06933.11 RUS70669.1 - 5.7 5.0 21.5 8.7 4.4 21.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Apt1 PF10351.9 RUS70669.1 - 6.9 5.4 16.4 12 4.6 16.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 RUS70669.1 - 8.8 4.0 17.6 17 3.0 17.6 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LRR_4 PF12799.7 RUS70670.1 - 5.1e-10 39.4 8.9 0.00012 22.4 0.8 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS70670.1 - 6e-09 35.6 1.1 2.6e-08 33.6 1.1 2.2 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS70670.1 - 2.8e-08 33.4 7.3 1.9e-06 27.5 1.7 2.7 3 0 0 3 3 3 2 Leucine rich repeat NTP_transf_8 PF12281.8 RUS70670.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase Endonuclease_7 PF02945.15 RUS70670.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII Somatomedin_B PF01033.17 RUS70673.1 - 1.1e-05 25.7 13.1 2.6e-05 24.5 13.1 1.7 1 0 0 1 1 1 1 Somatomedin B domain Nop14 PF04147.12 RUS70673.1 - 0.0019 16.5 35.1 0.0025 16.1 35.1 1.1 1 0 0 1 1 1 1 Nop14-like family CCSAP PF15748.5 RUS70673.1 - 0.002 18.3 13.2 0.0028 17.9 13.2 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Mpp10 PF04006.12 RUS70673.1 - 0.029 12.8 36.7 0.039 12.4 36.7 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS70673.1 - 0.041 13.3 36.4 0.057 12.8 36.4 1.1 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 RUS70673.1 - 0.044 13.9 3.3 0.064 13.4 3.3 1.3 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 RUS70673.1 - 0.044 13.1 31.8 0.059 12.7 31.8 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 RUS70673.1 - 0.13 12.1 16.1 0.16 11.8 16.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 RUS70673.1 - 0.19 10.0 28.7 0.24 9.6 28.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 RUS70673.1 - 0.28 10.6 17.7 0.39 10.1 17.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RNA_polI_A34 PF08208.11 RUS70673.1 - 0.33 11.0 28.1 0.46 10.5 28.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Mem_trans PF03547.18 RUS70673.1 - 0.35 9.2 1.3 0.32 9.3 1.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DNA_pol_phi PF04931.13 RUS70673.1 - 0.76 7.8 46.0 1 7.4 46.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi MDFI PF15316.6 RUS70673.1 - 0.98 9.5 15.7 2 8.4 15.6 1.6 1 1 0 1 1 1 0 MyoD family inhibitor FAM60A PF15396.6 RUS70673.1 - 1 9.3 8.3 1.9 8.5 8.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 RUS70673.1 - 1.1 8.0 17.3 1.4 7.6 17.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 RUS70673.1 - 1.5 9.2 19.2 2.5 8.5 19.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS70673.1 - 3.4 6.3 19.9 4.6 5.9 19.9 1.1 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 RUS70673.1 - 3.5 6.7 26.9 4.9 6.2 26.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 PA26 PF04636.13 RUS70673.1 - 4.4 6.1 9.8 5.9 5.7 9.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RP-C_C PF11800.8 RUS70673.1 - 4.6 7.3 11.2 7.2 6.7 11.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S64 PF08192.11 RUS70673.1 - 4.9 5.5 12.6 7 5.0 12.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 RUS70673.1 - 4.9 6.6 23.0 6.9 6.1 23.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Na_trans_assoc PF06512.13 RUS70673.1 - 5.3 7.3 25.3 8.8 6.5 25.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Tim54 PF11711.8 RUS70673.1 - 6.2 5.5 27.5 9.3 4.9 27.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Apt1 PF10351.9 RUS70673.1 - 6.4 5.5 12.1 8.7 5.1 12.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4045 PF13254.6 RUS70673.1 - 7.8 6.0 20.2 12 5.4 20.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDRGK PF09756.9 RUS70673.1 - 8.3 5.9 41.1 12 5.4 41.1 1.2 1 0 0 1 1 1 0 DDRGK domain Gti1_Pac2 PF09729.9 RUS70673.1 - 8.9 6.4 11.3 14 5.7 11.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 RUS70673.1 - 9.6 5.1 12.3 13 4.6 12.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC27 PF09507.10 RUS70673.1 - 9.7 5.5 29.5 14 5.0 29.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Innexin PF00876.18 RUS70674.1 - 4.2e-69 233.5 10.0 5.1e-69 233.2 10.0 1.0 1 0 0 1 1 1 1 Innexin Peptidase_C14 PF00656.22 RUS70675.1 - 7.9e-33 114.4 0.0 1.3e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 RUS70675.1 - 2.2e-25 88.7 7.6 9.9e-14 51.4 0.7 2.5 2 0 0 2 2 2 2 Death effector domain DUF3439 PF11921.8 RUS70675.1 - 0.07 13.1 4.2 0.16 11.9 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CPSase_L_D2 PF02786.17 RUS70676.1 - 4.3e-108 359.7 0.1 3.1e-78 262.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RUS70676.1 - 5.9e-50 168.4 0.0 1.4e-48 164.0 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RUS70676.1 - 6.7e-44 149.9 0.0 2e-43 148.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 RUS70676.1 - 3.1e-40 137.3 1.0 8.5e-40 135.9 1.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 RUS70676.1 - 1.2e-15 57.5 0.0 8.1e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 RUS70676.1 - 1e-13 51.2 0.0 2.7e-12 46.7 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 RUS70676.1 - 2.4e-12 46.8 0.1 5.6e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 RUS70676.1 - 6.7e-12 45.3 0.0 0.00013 21.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 RUS70676.1 - 7.9e-05 22.8 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 RUS70676.1 - 0.00032 20.5 0.5 0.055 13.2 0.5 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 RUS70676.1 - 0.0014 18.5 0.0 0.34 10.7 0.0 3.2 3 0 0 3 3 3 1 DJ-1/PfpI family HTH_23 PF13384.6 RUS70676.1 - 0.054 13.3 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain ATP-grasp_5 PF13549.6 RUS70676.1 - 0.096 12.1 0.0 15 5.0 0.0 2.7 2 1 0 2 2 2 0 ATP-grasp domain Nif11 PF07862.11 RUS70676.1 - 0.11 12.8 0.0 4.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Nif11 domain ATP_synth_reg PF14960.6 RUS70678.1 - 1.1e-13 50.4 0.2 1.4e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 ATP synthase regulation Ubiq_cyt_C_chap PF03981.12 RUS70680.1 - 1.6e-27 96.3 0.2 2.3e-27 95.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Popeye PF04831.13 RUS70680.1 - 0.024 14.8 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Popeye protein conserved region Sec6 PF06046.13 RUS70681.1 - 5.2e-110 368.5 10.2 5.2e-110 368.5 10.2 1.9 2 1 0 2 2 2 1 Exocyst complex component Sec6 SOAR PF16533.5 RUS70681.1 - 0.044 13.8 5.8 0.031 14.2 1.0 2.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 RUS70681.1 - 0.089 13.3 1.2 0.42 11.1 0.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 RUS70681.1 - 0.16 12.0 10.3 2.5 8.1 0.3 3.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 RUS70681.1 - 7.1 7.0 11.6 10 6.5 2.7 4.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 RUS70682.1 - 7.9e-27 94.4 7.7 8.9e-27 94.2 7.7 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein ATG16 PF08614.11 RUS70682.1 - 0.00018 21.8 6.4 0.00026 21.3 6.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF885 PF05960.11 RUS70682.1 - 0.0021 17.8 2.2 0.0023 17.6 2.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Laminin_II PF06009.12 RUS70682.1 - 0.12 12.4 1.5 0.53 10.3 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.18 RUS70682.1 - 0.14 12.0 12.7 0.22 11.4 12.7 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Senescence PF06911.12 RUS70682.1 - 0.19 12.0 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Senescence-associated protein DivIVA PF05103.13 RUS70682.1 - 0.88 9.7 9.6 1.1e+02 2.9 9.9 2.8 1 1 0 1 1 1 0 DivIVA protein H-kinase_dim PF02895.14 RUS70682.1 - 1.8 9.0 5.8 28 5.2 5.7 2.5 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain V-ATPase_G_2 PF16999.5 RUS70682.1 - 2.4 8.6 10.4 0.75 10.2 7.4 1.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 RUS70682.1 - 8.4 6.7 13.7 7.8 6.8 9.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_transf_22 PF03901.17 RUS70683.1 - 1.6e-08 34.3 0.8 1.9e-07 30.7 0.6 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.17 RUS70684.1 - 2.5e-08 33.6 3.0 2.8e-05 23.5 0.7 2.2 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family FMN_bind_2 PF04299.12 RUS70684.1 - 3.1 7.5 7.1 14 5.4 0.8 2.5 2 0 0 2 2 2 0 Putative FMN-binding domain Pentapeptide_4 PF13599.6 RUS70686.1 - 1.9e-37 127.3 92.3 1.6e-05 25.0 9.1 7.4 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) CD34_antigen PF06365.12 RUS70687.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.6 RUS70687.1 - 0.023 14.9 0.1 0.035 14.3 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM51 PF15345.6 RUS70687.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 CYYR1 PF10873.8 RUS70687.1 - 0.04 14.4 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 RUS70687.1 - 0.046 14.6 0.0 0.079 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RUS70687.1 - 0.064 13.1 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 TMEM154 protein family LST1 PF05083.13 RUS70687.1 - 0.07 13.4 0.4 0.13 12.5 0.4 1.4 1 0 0 1 1 1 0 LST-1 protein Cytomega_TRL10 PF06084.11 RUS70687.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein MLANA PF14991.6 RUS70687.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Herpes_gE PF02480.16 RUS70687.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Tweety PF04906.13 RUS70687.1 - 0.27 9.8 0.4 0.38 9.4 0.4 1.1 1 0 0 1 1 1 0 Tweety IFT57 PF10498.9 RUS70688.1 - 1.4e-150 501.3 7.7 1.6e-150 501.1 7.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 RUS70688.1 - 0.00027 19.9 12.2 0.00042 19.3 12.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Rogdi_lz PF10259.9 RUS70688.1 - 0.0035 16.8 0.4 0.0056 16.2 0.4 1.3 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Fez1 PF06818.15 RUS70688.1 - 0.0038 17.7 8.5 0.0038 17.7 8.5 2.4 1 1 0 2 2 2 1 Fez1 Laminin_II PF06009.12 RUS70688.1 - 0.006 16.6 2.9 0.015 15.3 2.9 1.7 1 0 0 1 1 1 1 Laminin Domain II Spectrin PF00435.21 RUS70688.1 - 0.015 15.8 3.0 0.015 15.8 3.0 2.5 2 0 0 2 2 2 0 Spectrin repeat Mod_r PF07200.13 RUS70688.1 - 0.018 15.2 7.9 0.023 14.8 5.6 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Radical_SAM PF04055.21 RUS70688.1 - 0.026 14.9 0.4 0.61 10.5 0.0 2.9 2 1 0 2 2 2 0 Radical SAM superfamily EzrA PF06160.12 RUS70688.1 - 0.027 12.7 5.3 0.06 11.5 5.3 1.6 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LOH1CR12 PF10158.9 RUS70688.1 - 0.035 14.1 0.6 0.062 13.3 0.6 1.4 1 0 0 1 1 1 0 Tumour suppressor protein DUF4051 PF13260.6 RUS70688.1 - 0.043 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF2524 PF10732.9 RUS70688.1 - 0.072 13.4 3.9 0.22 11.8 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF3829 PF12889.7 RUS70688.1 - 0.097 12.1 0.9 0.19 11.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) MCPsignal PF00015.21 RUS70688.1 - 0.1 12.4 1.4 0.22 11.3 1.1 1.7 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dad1 PF08649.10 RUS70688.1 - 0.16 12.2 1.2 3.3 8.0 0.3 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad1 COG2 PF06148.11 RUS70688.1 - 0.48 10.5 6.7 0.61 10.2 0.8 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 RUS70688.1 - 0.61 9.1 9.5 1 8.4 9.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 RUS70688.1 - 0.72 10.1 2.5 10 6.5 1.0 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SpecificRecomb PF10136.9 RUS70688.1 - 0.87 7.8 4.6 1.2 7.4 4.6 1.2 1 0 0 1 1 1 0 Site-specific recombinase YojJ PF10372.9 RUS70688.1 - 1 9.5 4.7 15 5.7 0.4 3.4 2 2 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus FAM76 PF16046.5 RUS70688.1 - 1.1 8.5 7.8 2 7.7 7.8 1.4 1 0 0 1 1 1 0 FAM76 protein COG5 PF10392.9 RUS70688.1 - 1.3 9.2 6.7 11 6.2 1.6 2.7 1 1 0 2 2 2 0 Golgi transport complex subunit 5 CENP-H PF05837.12 RUS70688.1 - 1.8 9.0 12.8 0.59 10.6 5.5 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 RUS70688.1 - 4.9 7.6 9.9 28 5.1 9.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 RUS70688.1 - 8.7 6.4 9.6 2.1 8.4 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_1 PF00515.28 RUS70689.1 - 8.3e-12 44.4 0.8 3.8e-06 26.5 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS70689.1 - 1e-05 25.3 4.6 5.5e-05 23.0 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70689.1 - 0.0022 18.1 3.4 0.33 11.3 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS70689.1 - 0.0042 17.0 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70689.1 - 0.013 15.7 9.0 0.017 15.4 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS70689.1 - 0.021 15.6 2.2 0.17 12.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 RUS70689.1 - 0.024 14.1 0.5 0.041 13.4 0.1 1.6 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 RUS70689.1 - 0.044 14.3 0.0 0.044 14.3 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS70689.1 - 0.044 14.0 0.8 0.085 13.1 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RUS70689.1 - 0.058 14.0 1.2 0.058 14.0 1.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ago_N_1 PF18351.1 RUS70689.1 - 0.059 13.8 0.4 0.48 10.9 0.0 2.3 1 1 1 2 2 2 0 Fungal Argonaute N-terminal domain DUF1284 PF06935.11 RUS70689.1 - 0.41 11.1 1.8 3.3 8.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1284) TPR_10 PF13374.6 RUS70689.1 - 0.52 10.2 4.3 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Arm PF00514.23 RUS70690.1 - 1.2e-05 25.1 10.2 0.0066 16.5 0.1 4.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RUS70690.1 - 0.0034 17.5 1.0 0.012 15.7 0.2 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 RUS70690.1 - 0.0082 16.1 3.8 0.055 13.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF383 PF04063.14 RUS70690.1 - 0.018 14.7 0.5 0.066 12.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF383) HEAT PF02985.22 RUS70690.1 - 0.032 14.5 0.5 0.4 11.1 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 RUS70690.1 - 0.037 14.4 0.4 0.94 9.9 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats Atx10homo_assoc PF09759.9 RUS70690.1 - 0.26 11.3 1.6 0.82 9.7 0.0 2.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain FDC-SP PF15215.6 RUS70692.1 - 1.5 9.4 10.3 0.2 12.2 2.3 2.3 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide ATP-synt_F PF01990.17 RUS70694.1 - 2e-30 105.0 0.1 2.4e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CBS PF00571.28 RUS70694.1 - 0.11 13.0 0.1 1.2 9.6 0.0 2.5 2 1 0 2 2 2 0 CBS domain ubiquitin PF00240.23 RUS70695.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RUS70695.1 - 0.16 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Peptidase_M56 PF05569.11 RUS70695.1 - 0.16 11.1 0.0 0.16 11.1 0.0 2.0 2 1 0 2 2 2 0 BlaR1 peptidase M56 DUF2198 PF09964.9 RUS70695.1 - 2 8.5 6.5 1.3 9.2 1.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) TPMT PF05724.11 RUS70696.1 - 1.2e-31 110.0 0.0 1.6e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 RUS70696.1 - 1e-07 32.5 0.0 3.2e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS70696.1 - 4.4e-07 30.5 0.0 1.1e-05 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS70696.1 - 7.1e-07 29.2 0.0 9.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS70696.1 - 8.4e-05 23.2 0.0 0.00029 21.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 RUS70696.1 - 0.004 16.7 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_31 PF13847.6 RUS70696.1 - 0.015 15.1 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Hemopexin PF00045.19 RUS70696.1 - 0.028 14.3 0.9 0.07 13.1 0.9 1.7 1 0 0 1 1 1 0 Hemopexin Methyltransf_30 PF05430.11 RUS70696.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF4962 PF16332.5 RUS70696.1 - 0.06 11.8 0.2 0.083 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DUF4559 PF15112.6 RUS70696.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TPMT PF05724.11 RUS70697.1 - 2.1e-16 60.3 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 RUS70697.1 - 0.00075 19.4 0.0 0.00077 19.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS70697.1 - 0.0073 17.0 0.0 0.016 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 RUS70697.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RUS70697.1 - 0.044 14.5 0.0 0.083 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TUDOR_5 PF18359.1 RUS70697.1 - 0.17 11.6 0.2 0.28 10.9 0.2 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 zf-B_box PF00643.24 RUS70698.1 - 1.9e-09 37.5 5.6 1.9e-09 37.5 5.6 2.9 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 RUS70698.1 - 3.3e-08 33.4 4.3 3.3e-08 33.4 4.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS70698.1 - 3.1e-07 30.1 2.0 3.1e-07 30.1 2.0 2.9 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS70698.1 - 4.2e-07 29.8 4.5 4.2e-07 29.8 4.5 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS70698.1 - 3e-06 27.4 7.1 3e-06 27.4 7.1 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS70698.1 - 0.00035 20.3 4.3 0.00035 20.3 4.3 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RUS70698.1 - 0.0014 18.4 4.1 0.0014 18.4 4.1 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RUS70698.1 - 0.004 17.3 2.5 0.004 17.3 2.5 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING CEBP_ZZ PF16366.5 RUS70698.1 - 0.013 15.7 8.1 0.91 9.8 1.2 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_11 PF17123.5 RUS70698.1 - 0.02 14.7 4.9 0.021 14.6 3.5 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 RUS70698.1 - 0.37 10.9 4.6 2.6 8.2 0.2 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 RUS70698.1 - 0.69 9.8 19.9 0.025 14.4 8.1 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sec20 PF03908.13 RUS70698.1 - 2.9 7.9 5.9 4.1 7.4 2.3 2.6 1 1 1 2 2 2 0 Sec20 SGS PF05002.15 RUS70699.1 - 2.1e-37 127.1 3.7 2.1e-37 127.1 3.7 2.0 2 0 0 2 2 1 1 SGS domain TPR_1 PF00515.28 RUS70699.1 - 8.7e-15 53.8 13.8 2.1e-07 30.4 0.3 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat CS PF04969.16 RUS70699.1 - 7.2e-14 52.6 3.2 1.5e-13 51.5 3.2 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 RUS70699.1 - 3.1e-13 48.7 10.4 3.2e-05 23.7 0.2 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS70699.1 - 3.2e-09 36.9 1.5 6.2e-09 36.0 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 RUS70699.1 - 1.3e-07 32.1 0.7 2.6e-07 31.2 0.7 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 RUS70699.1 - 4.3e-07 30.3 4.0 3.5e-05 24.2 2.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS70699.1 - 5.7e-07 30.1 0.3 5.7e-07 30.1 0.3 2.8 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS70699.1 - 1.1e-06 28.1 5.8 0.00014 21.5 1.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 RUS70699.1 - 2.5e-05 24.7 0.7 0.041 14.7 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70699.1 - 2.5e-05 24.1 7.1 0.002 18.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70699.1 - 8e-05 22.9 4.1 0.0033 17.7 2.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS70699.1 - 8.4e-05 22.3 2.9 0.013 15.5 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS70699.1 - 0.00085 19.1 2.3 0.15 12.0 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS70699.1 - 0.0029 17.7 0.9 0.029 14.5 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 RUS70699.1 - 0.0032 17.5 6.2 0.0094 16.0 1.9 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 RUS70699.1 - 0.013 15.6 0.3 1.9 8.7 0.1 2.5 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.6 RUS70699.1 - 0.013 15.8 1.9 0.16 12.4 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RUS70699.1 - 0.03 14.8 1.2 0.03 14.8 1.2 2.2 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation SPO22 PF08631.10 RUS70699.1 - 0.063 12.7 1.9 4.4 6.7 0.2 3.0 1 1 2 3 3 3 0 Meiosis protein SPO22/ZIP4 like HEPN PF05168.14 RUS70699.1 - 0.07 13.3 3.4 0.47 10.6 1.0 2.8 4 0 0 4 4 2 0 HEPN domain RPN6_N PF18055.1 RUS70699.1 - 0.074 13.4 1.6 0.22 11.9 1.5 1.9 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2057 PF09829.9 RUS70699.1 - 0.15 12.3 3.1 0.19 11.9 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_3 PF07720.12 RUS70699.1 - 0.17 11.9 6.1 2 8.5 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS70699.1 - 4.4 8.1 7.0 52 4.8 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DivIC PF04977.15 RUS70700.1 - 0.029 14.2 0.3 0.029 14.2 0.3 2.5 2 1 1 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 RUS70700.1 - 0.052 13.5 0.5 0.052 13.5 0.5 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 RUS70700.1 - 0.074 13.5 1.2 0.074 13.5 1.2 2.2 2 1 0 2 2 2 0 Snapin/Pallidin E2F_CC-MB PF16421.5 RUS70700.1 - 0.36 11.2 4.4 2.5 8.5 2.5 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain YabA PF06156.13 RUS70700.1 - 1.4 9.6 4.6 0.8 10.4 1.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA HSCB_C PF07743.13 RUS70700.1 - 1.7 9.2 5.0 16 6.0 0.9 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain bZIP_1 PF00170.21 RUS70700.1 - 2.1 8.5 5.7 0.27 11.4 1.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor FAM76 PF16046.5 RUS70700.1 - 3.5 6.9 12.6 1.1 8.5 5.6 2.2 1 1 1 2 2 2 0 FAM76 protein Ubiquitin_4 PF18036.1 RUS70702.1 - 1.5e-29 101.9 0.7 2e-29 101.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 RUS70702.1 - 0.00042 20.0 0.0 0.0092 15.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family MauJ PF17419.2 RUS70702.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Methylamine utilization protein MauJ SURF6 PF04935.12 RUS70702.1 - 0.032 14.0 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 TP1 PF02079.16 RUS70702.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Nuclear transition protein 1 Rad60-SLD PF11976.8 RUS70702.1 - 0.11 12.3 0.1 0.81 9.6 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like EF-hand_1 PF00036.32 RUS70703.1 - 2.2e-33 111.3 10.5 2.1e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS70703.1 - 1.2e-31 109.0 5.6 4.2e-15 55.9 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS70703.1 - 3.7e-28 95.0 9.5 1.1e-07 31.2 0.0 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RUS70703.1 - 3.8e-21 74.7 5.8 3.2e-11 42.9 0.1 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS70703.1 - 2.6e-19 67.8 10.9 5.5e-06 25.6 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS70703.1 - 4.4e-09 36.5 0.2 7.3e-08 32.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS70703.1 - 9.2e-09 35.6 2.6 8.4e-07 29.3 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS70703.1 - 2.4e-07 30.7 3.5 0.0022 17.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 RUS70703.1 - 0.0082 17.0 0.2 2.3 9.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 RUS70703.1 - 0.01 16.0 4.2 0.051 13.8 0.8 2.8 1 1 2 3 3 3 0 Dockerin type I domain SurA_N_3 PF13624.6 RUS70703.1 - 0.012 15.4 1.6 0.078 12.8 0.6 2.0 1 1 0 2 2 2 0 SurA N-terminal domain TerB PF05099.13 RUS70703.1 - 0.013 15.5 1.7 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB HD-ZIP_N PF04618.12 RUS70703.1 - 0.028 14.9 1.6 0.76 10.3 0.0 2.8 1 1 1 3 3 3 0 HD-ZIP protein N terminus VCBS PF13517.6 RUS70703.1 - 0.069 13.7 0.1 0.24 12.0 0.1 2.1 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1456 PF07308.13 RUS70703.1 - 0.079 13.3 1.3 15 6.0 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) NADPH_Ox PF08414.10 RUS70703.1 - 0.088 13.2 1.0 0.3 11.5 0.4 2.0 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase EF-hand_14 PF17959.1 RUS70703.1 - 0.1 12.9 1.7 8.4 6.8 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 RUS70703.1 - 0.21 11.4 4.6 0.13 12.1 0.3 2.3 1 1 1 2 2 2 0 SurA N-terminal domain JmjN PF02375.17 RUS70703.1 - 0.49 10.4 2.4 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 jmjN domain Somatomedin_B PF01033.17 RUS70704.1 - 0.00024 21.4 11.8 0.00024 21.4 11.8 2.0 2 0 0 2 2 2 1 Somatomedin B domain TPR_2 PF07719.17 RUS70705.1 - 2.4e-11 42.9 3.5 0.00013 21.8 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS70705.1 - 1e-09 37.8 1.7 9.3e-05 22.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70705.1 - 4.1e-08 32.8 0.9 0.0023 18.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS70705.1 - 4.3e-08 33.2 1.5 1.4e-05 25.1 0.8 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS70705.1 - 1.6e-05 25.4 5.0 1.6e-05 25.4 5.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70705.1 - 6.9e-05 23.1 2.7 0.0018 18.5 1.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS70705.1 - 7.8e-05 22.8 0.1 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS70705.1 - 0.00016 21.3 3.5 0.049 13.3 0.1 2.9 2 1 1 3 3 3 2 TPR repeat TPR_10 PF13374.6 RUS70705.1 - 0.00049 19.9 6.2 0.0047 16.7 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS70705.1 - 0.0012 19.4 6.2 0.045 14.6 0.3 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS70705.1 - 0.0063 17.0 1.8 0.0063 17.0 1.8 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS70705.1 - 0.033 14.8 4.3 12 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 RUS70705.1 - 0.17 10.8 0.4 0.51 9.2 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 RUS70705.1 - 0.52 11.1 3.0 2.5 9.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 RUS70705.1 - 0.64 10.2 8.4 2.8 8.2 1.1 2.5 1 1 0 2 2 2 0 HemY protein N-terminus Glyco_transf_10 PF00852.19 RUS70706.1 - 8.1e-33 113.6 0.2 1.1e-32 113.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribosomal_L37ae PF01780.19 RUS70706.1 - 0.058 13.5 0.8 0.1 12.7 0.8 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family Hormone_3 PF00159.18 RUS70706.1 - 0.11 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide ECH_1 PF00378.20 RUS70707.1 - 2.1e-39 135.4 0.0 2.5e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS70707.1 - 1.2e-19 71.0 0.1 7.6e-17 61.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase OrsD PF12013.8 RUS70708.1 - 0.00021 21.7 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 RUS70708.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type TFIIA PF03153.13 RUS70709.1 - 0.29 11.1 23.6 0.39 10.7 23.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 RUS70709.1 - 1.3 8.4 11.9 0.65 9.4 5.7 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4834 PF16118.5 RUS70709.1 - 5.2 8.1 7.5 2.4 9.2 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4550 PF15084.6 RUS70710.1 - 2e-32 111.4 0.0 5.8e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) CD225 PF04505.12 RUS70711.1 - 7.4e-15 54.9 0.5 1e-14 54.4 0.5 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Yip1 PF04893.17 RUS70711.1 - 0.00066 19.4 0.3 0.00085 19.1 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain VIT1 PF01988.19 RUS70711.1 - 0.012 15.5 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 VIT family Voltage_CLC PF00654.20 RUS70711.1 - 0.021 14.1 0.7 0.025 13.8 0.7 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Adeno_E3_CR2 PF02439.15 RUS70711.1 - 2.7 7.8 7.0 0.45 10.3 0.8 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 zf-C2H2 PF00096.26 RUS70712.1 - 1.1e-23 82.3 30.3 2.2e-05 24.7 0.7 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS70712.1 - 1.9e-19 68.7 27.2 0.00059 20.5 0.7 6.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS70712.1 - 4.7e-15 55.2 28.0 5.2e-06 26.6 0.3 6.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS70712.1 - 7.7e-07 29.0 26.1 0.041 13.9 0.2 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS70712.1 - 1.2e-06 28.7 19.4 0.2 12.0 0.1 5.9 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS70712.1 - 0.00015 22.0 21.2 0.35 11.3 0.1 6.0 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-BED PF02892.15 RUS70712.1 - 0.011 15.7 24.0 0.16 12.0 0.4 5.9 2 1 3 5 5 5 0 BED zinc finger zinc_ribbon_15 PF17032.5 RUS70712.1 - 0.037 14.8 8.6 2.1 9.2 0.6 2.9 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_11 PF16622.5 RUS70712.1 - 0.058 13.2 27.5 0.62 9.9 0.3 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RUS70712.1 - 0.06 13.5 11.2 0.82 9.8 1.1 3.8 2 1 0 3 3 3 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 RUS70712.1 - 0.079 13.6 5.7 1.1 9.9 0.0 3.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF5032 PF16435.5 RUS70712.1 - 0.086 12.3 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5032) Elf1 PF05129.13 RUS70712.1 - 0.16 12.0 9.6 3.5 7.7 0.1 3.4 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 RUS70712.1 - 0.22 11.8 13.8 2 8.7 2.0 3.8 2 1 1 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 RUS70712.1 - 0.66 10.0 9.4 1.2 9.2 0.6 3.1 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 RUS70712.1 - 0.7 9.5 15.6 5.3 6.7 0.1 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 RUS70712.1 - 1.2 9.1 9.4 17 5.4 0.4 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 RUS70712.1 - 2.2 8.7 17.5 5.6 7.4 2.2 4.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Sprouty PF05210.13 RUS70712.1 - 4.9 7.6 11.9 3.9 7.9 2.4 2.6 2 0 0 2 2 2 0 Sprouty protein (Spry) ADK_lid PF05191.14 RUS70712.1 - 5.1 7.2 5.8 12 6.0 1.3 3.3 2 2 0 2 2 2 0 Adenylate kinase, active site lid LIM PF00412.22 RUS70712.1 - 8 6.8 13.5 0.57 10.4 6.6 2.7 3 0 0 3 3 3 0 LIM domain NUDIX_2 PF13869.6 RUS70713.1 - 2e-76 255.8 0.0 2.3e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ank_2 PF12796.7 RUS70714.1 - 9.8e-47 157.5 7.8 6.2e-17 62.0 1.4 5.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 RUS70714.1 - 5.2e-35 118.4 5.3 0.00075 19.8 0.0 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RUS70714.1 - 9.5e-33 108.6 7.0 0.0041 17.5 0.0 9.2 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS70714.1 - 5.8e-32 109.4 4.2 2.1e-08 34.3 0.0 7.8 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS70714.1 - 5.9e-32 109.6 7.5 5.9e-09 36.3 0.0 7.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) DUF4955 PF16315.5 RUS70714.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) DUF4897 PF16238.5 RUS70715.1 - 0.085 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) Sema PF01403.19 RUS70716.1 - 3.6e-21 75.5 1.5 7.6e-21 74.4 1.2 1.7 3 0 0 3 3 3 1 Sema domain TIG PF01833.24 RUS70716.1 - 3.7e-21 75.0 0.7 5.2e-11 42.5 0.0 3.0 3 0 0 3 3 3 2 IPT/TIG domain PSI PF01437.25 RUS70716.1 - 2e-06 28.2 18.6 2e-06 28.2 18.6 2.3 2 0 0 2 2 2 1 Plexin repeat Cys_box PF17869.1 RUS70716.1 - 0.24 11.5 3.9 0.73 10.0 3.9 1.8 1 0 0 1 1 1 0 Anosmin cysteine rich domain 7tm_1 PF00001.21 RUS70717.1 - 8.8e-20 71.1 10.1 1.6e-19 70.3 10.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS70717.1 - 4.2e-08 32.8 10.7 3.9e-07 29.7 10.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RUS70717.1 - 5.8e-06 25.9 11.7 1.6e-05 24.4 0.6 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS70717.1 - 0.00015 21.5 6.1 0.00015 21.5 6.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SURF2 PF05477.11 RUS70718.1 - 0.65 9.6 6.2 0.91 9.2 6.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) adh_short_C2 PF13561.6 RUS70719.1 - 4e-46 157.5 0.0 5.4e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS70719.1 - 3e-39 134.5 0.1 3.9e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS70719.1 - 1.5e-09 38.0 0.1 2.2e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RUS70719.1 - 0.0044 16.2 0.1 0.0062 15.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pro_isomerase PF00160.21 RUS70720.1 - 1.2e-67 227.1 3.7 9.7e-40 136.4 0.5 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EGF_2 PF07974.13 RUS70721.1 - 0.0071 16.7 6.1 0.025 15.0 6.1 2.0 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.7 RUS70721.1 - 0.94 9.7 8.5 3.9 7.8 8.5 2.2 1 0 0 1 1 1 0 EGF domain TMEM237 PF15383.6 RUS70722.1 - 1.5e-41 142.2 0.0 1.5e-41 142.2 0.0 1.5 2 0 0 2 2 2 1 Transmembrane protein 237 Androgen_recep PF02166.16 RUS70722.1 - 0.86 8.4 6.6 1.1 8.0 6.6 1.1 1 0 0 1 1 1 0 Androgen receptor DJ-1_PfpI PF01965.24 RUS70723.1 - 9.3e-07 28.8 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 DJ-1/PfpI family BBS2_C PF14782.6 RUS70724.1 - 4.5e-174 579.3 0.0 4.4e-172 572.7 0.0 2.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 RUS70724.1 - 7.9e-46 154.5 0.1 3.3e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 RUS70724.1 - 4.4e-07 29.9 0.1 0.0058 16.7 0.1 2.8 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 RUS70724.1 - 0.00028 21.4 0.3 0.018 15.6 0.2 3.1 2 1 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_N PF14781.6 RUS70724.1 - 0.0007 19.5 0.1 0.0046 16.8 0.0 2.5 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 RUS70724.1 - 0.056 12.5 0.1 6 5.8 0.0 2.4 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Lectin_C PF00059.21 RUS70726.1 - 5.6e-16 59.2 0.0 1.2e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Amino_oxidase PF01593.24 RUS70727.1 - 4.5e-65 220.7 0.1 4.1e-51 174.7 0.0 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS70727.1 - 1.8e-10 40.9 0.1 5.9e-10 39.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RUS70727.1 - 1.1e-07 31.4 1.0 4.6e-06 26.1 1.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS70727.1 - 2.4e-06 27.6 0.4 0.0004 20.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 RUS70727.1 - 1.7e-05 24.5 0.1 0.00039 20.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RUS70727.1 - 6.2e-05 22.2 0.0 0.00027 20.1 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 RUS70727.1 - 0.00013 21.3 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 RUS70727.1 - 0.0013 17.5 2.5 0.082 11.6 0.0 3.8 4 1 1 5 5 5 1 HI0933-like protein FAD_binding_2 PF00890.24 RUS70727.1 - 0.0022 17.1 0.3 0.0089 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 RUS70727.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ETRAMP PF09716.10 RUS70727.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GIDA PF01134.22 RUS70727.1 - 0.035 13.2 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4969 PF16339.5 RUS70727.1 - 0.061 13.7 0.2 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Eno-Rase_NADH_b PF12242.8 RUS70727.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Usp PF00582.26 RUS70728.1 - 3.7e-23 82.6 0.0 4.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF563 PF04577.14 RUS70729.1 - 3.7e-28 99.1 0.1 5.2e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) WD40 PF00400.32 RUS70730.1 - 1e-41 140.1 41.9 2e-06 28.4 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 RUS70730.1 - 2e-11 43.6 2.6 4.1e-11 42.6 2.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS70730.1 - 8.5e-10 38.3 0.8 1.8e-09 37.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 RUS70730.1 - 3.4e-07 29.3 14.6 0.0042 15.8 0.1 6.2 1 1 5 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS70730.1 - 5.7e-05 22.6 0.2 0.0025 17.2 0.2 2.4 1 1 0 1 1 1 1 WD40-like domain F-box_4 PF15966.5 RUS70730.1 - 0.0009 19.1 1.6 0.0009 19.1 1.6 2.3 2 0 0 2 2 2 1 F-box YfkB PF08756.10 RUS70730.1 - 0.058 13.2 0.4 0.85 9.4 0.0 2.7 3 0 0 3 3 3 0 YfkB-like domain DUF4611 PF15387.6 RUS70730.1 - 0.069 13.4 9.2 0.35 11.1 9.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) EpCAM_N PF18635.1 RUS70730.1 - 0.72 10.1 4.4 7.1 6.9 0.2 3.8 4 0 0 4 4 4 0 Epithelial cell adhesion molecule N-terminal domain Pox_A28 PF04584.14 RUS70730.1 - 3.4 7.8 5.7 2.2 8.5 0.9 2.8 2 1 0 2 2 2 0 Poxvirus A28 family Hormone_recep PF00104.30 RUS70731.1 - 3.8e-38 131.1 0.3 5.4e-38 130.7 0.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS70731.1 - 5.2e-31 106.9 12.5 9.2e-31 106.1 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2944 PF11161.8 RUS70731.1 - 0.079 12.8 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) RVT_1 PF00078.27 RUS70732.1 - 1.3e-07 31.4 0.7 8e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 RUS70733.1 - 1.2e-45 155.9 0.0 1.5e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70733.1 - 2.3e-24 86.1 0.0 2.9e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS70733.1 - 2e-05 24.7 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS70733.1 - 2.7e-05 23.6 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS70733.1 - 0.0026 17.1 0.1 0.0037 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS70733.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RUS70733.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Tektin PF03148.14 RUS70734.1 - 7.4e-129 429.8 24.3 9.2e-129 429.5 24.3 1.1 1 0 0 1 1 1 1 Tektin family MitMem_reg PF13012.6 RUS70734.1 - 0.026 14.9 0.3 0.026 14.9 0.3 2.9 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function FlaC_arch PF05377.11 RUS70734.1 - 0.17 12.3 2.5 5.1 7.6 0.1 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1788 PF08747.11 RUS70734.1 - 0.24 11.4 1.1 9.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Sec8_exocyst PF04048.14 RUS70734.1 - 0.27 11.1 7.0 3 7.7 0.2 3.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Thiamine_BP PF01910.17 RUS70734.1 - 0.29 11.1 2.0 32 4.5 1.5 2.8 2 0 0 2 2 2 0 Thiamine-binding protein DUF1664 PF07889.12 RUS70734.1 - 1.9 8.5 13.0 1.5 8.8 0.0 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 RUS70734.1 - 5.4 6.5 15.0 1.3 8.6 0.2 3.7 2 2 0 4 4 4 0 fzo-like conserved region Cyclin_C PF02984.19 RUS70736.1 - 1.4 9.0 11.5 6 7.0 2.4 2.5 1 1 1 2 2 2 0 Cyclin, C-terminal domain TrkA_TMD PF18613.1 RUS70736.1 - 5.4 6.5 9.2 4.9 6.7 0.4 3.1 3 0 0 3 3 3 0 Tyrosine kinase receptor A trans-membrane domain BAF1_ABF1 PF04684.13 RUS70737.1 - 0.3 10.1 28.9 0.55 9.2 28.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BUD22 PF09073.10 RUS70737.1 - 0.98 8.7 48.9 1.8 7.8 48.9 1.4 1 0 0 1 1 1 0 BUD22 DUF4241 PF14025.6 RUS70738.1 - 0.064 13.5 0.3 0.24 11.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) Pet100 PF09803.9 RUS70739.1 - 0.088 13.3 0.1 6.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Pet100 DUF2681 PF10883.8 RUS70739.1 - 7.4 7.0 10.4 3.8 8.0 4.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) MWFE PF15879.5 RUS70740.1 - 2.3e-07 30.9 0.2 4.9e-07 29.8 0.2 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Nuc_deoxyrib_tr PF05014.15 RUS70741.1 - 3.8e-14 52.8 0.0 4.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF5628 PF18621.1 RUS70741.1 - 0.16 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5628) Peptidase_C2 PF00648.21 RUS70742.1 - 7e-85 284.6 0.0 7.9e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Astacin PF01400.24 RUS70743.1 - 4e-62 209.2 0.0 6.3e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Lectin_C PF00059.21 RUS70743.1 - 6.8e-06 26.8 0.1 2.1e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 RUS70743.1 - 0.012 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like 7tm_1 PF00001.21 RUS70744.1 - 2.3e-07 30.4 7.8 0.0012 18.3 0.0 2.6 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF1981 PF09324.10 RUS70744.1 - 0.005 16.7 3.3 2.3 8.1 0.2 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) SPX PF03105.19 RUS70744.1 - 0.038 13.9 0.3 0.05 13.5 0.3 1.1 1 0 0 1 1 1 0 SPX domain PDGF_N PF04692.13 RUS70744.1 - 3.4 8.5 11.6 0.41 11.5 4.3 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Cu2_monoox_C PF03712.15 RUS70745.1 - 0.025 14.1 0.3 34 3.9 0.0 3.8 1 1 4 5 5 5 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain HMw1_D2 PF18254.1 RUS70745.1 - 0.097 13.0 20.9 16 5.9 0.3 6.6 1 1 6 7 7 7 0 HMW1 domain 2 Queuosine_synth PF02547.15 RUS70745.1 - 0.098 11.8 3.5 5.9 5.9 0.1 3.1 2 1 1 3 3 3 0 Queuosine biosynthesis protein Cadherin PF00028.17 RUS70746.1 - 0.00058 20.2 0.1 0.12 12.8 0.1 2.2 2 0 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 RUS70747.1 - 0.04 14.3 0.0 0.074 13.5 0.0 1.4 1 1 0 1 1 1 0 Cadherin domain HMGL-like PF00682.19 RUS70748.1 - 9.1e-55 186.1 0.8 4.4e-46 157.6 0.4 2.0 1 1 1 2 2 2 2 HMGL-like DUF4838 PF16126.5 RUS70748.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Claudin_2 PF13903.6 RUS70749.1 - 8.1e-13 48.6 2.8 1.1e-12 48.1 2.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS70749.1 - 0.001 19.0 4.8 0.014 15.2 1.1 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RUS70749.1 - 0.0011 19.0 5.7 0.0095 15.9 5.7 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF973 PF06157.11 RUS70749.1 - 0.29 10.1 5.9 0.51 9.3 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) UPF0239 PF06783.11 RUS70749.1 - 0.48 10.6 1.1 8.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) PhoLip_ATPase_C PF16212.5 RUS70751.1 - 3.3e-84 282.5 27.3 3.3e-84 282.5 27.3 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RUS70751.1 - 3.7e-27 93.8 7.3 1.4e-26 91.9 7.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RUS70751.1 - 4.2e-13 49.2 0.0 4.1e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RUS70751.1 - 5.2e-09 35.9 0.0 2.3e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 RUS70751.1 - 5.3e-09 36.7 2.0 0.00059 20.2 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RUS70751.1 - 0.0079 16.0 0.1 0.028 14.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Urease_linker PF18473.1 RUS70752.1 - 8.2e-05 22.4 3.3 72 3.4 0.0 6.4 7 0 0 7 7 7 0 Urease subunit beta-alpha linker domain DUF1722 PF08349.11 RUS70752.1 - 0.21 11.9 7.0 24 5.3 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1722) BA14K PF07886.11 RUS70752.1 - 7.1 6.6 10.8 70 3.4 0.1 4.0 4 0 0 4 4 4 0 BA14K-like protein Claudin_3 PF06653.11 RUS70753.1 - 1.6e-08 34.6 4.2 2.4e-05 24.3 2.3 2.1 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RUS70753.1 - 2.2e-08 34.1 1.0 2.2e-08 34.1 1.0 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS70753.1 - 0.0013 18.6 8.1 0.016 15.1 8.1 2.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family MIG-14_Wnt-bd PF06664.12 RUS70753.1 - 0.029 13.6 2.9 0.05 12.8 1.3 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Amastin PF07344.11 RUS70753.1 - 0.087 12.7 8.8 0.022 14.6 3.0 2.3 2 1 0 2 2 2 0 Amastin surface glycoprotein CitMHS PF03600.16 RUS70753.1 - 2.6 7.1 11.6 0.17 11.1 6.1 1.6 2 0 0 2 2 2 0 Citrate transporter NDUF_B12 PF08122.12 RUS70754.1 - 1.2e-17 63.7 0.6 1.5e-17 63.4 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Exo_endo_phos PF03372.23 RUS70755.1 - 7.9e-07 28.8 0.0 1.3e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS70755.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase GTP_cyclohydroI PF01227.22 RUS70756.1 - 1.7e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I WD-3 PF09765.9 RUS70757.1 - 1.5e-51 175.5 0.3 1.7e-51 175.2 0.3 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 RUS70757.1 - 4.5e-26 90.8 4.8 7.2e-26 90.2 4.8 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 RUS70757.1 - 9.2e-07 29.1 8.0 1.9e-06 28.1 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 RUS70757.1 - 0.0062 16.8 1.3 0.012 15.8 1.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 RUS70757.1 - 0.032 14.2 6.0 0.039 13.9 2.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 RUS70757.1 - 0.048 13.7 4.3 0.18 11.9 4.3 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RUS70757.1 - 0.05 13.9 7.6 0.18 12.1 7.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 RUS70757.1 - 0.16 12.1 6.2 0.37 10.9 6.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 RUS70757.1 - 0.52 10.7 5.2 1.4 9.3 5.2 1.9 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 RUS70757.1 - 1.6 8.6 6.9 4 7.4 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Gram_pos_anchor PF00746.21 RUS70758.1 - 0.087 12.8 1.3 0.19 11.7 1.3 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF1011 PF06237.12 RUS70759.1 - 5.1e-33 113.4 9.5 5.1e-33 113.4 9.5 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF1011) MscL PF01741.18 RUS70759.1 - 1.6 9.0 4.3 2.4 8.5 0.1 2.7 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Alpha_kinase PF02816.18 RUS70760.1 - 5.8e-28 98.3 0.0 7.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Ank_4 PF13637.6 RUS70761.1 - 2.4e-39 133.2 7.1 4.2e-10 40.0 0.0 7.7 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS70761.1 - 3e-39 133.5 6.7 5.2e-14 52.6 0.1 5.1 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RUS70761.1 - 3e-35 119.1 13.6 1.9e-05 24.9 0.5 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 RUS70761.1 - 7.4e-29 96.6 10.2 0.00014 22.0 0.1 9.2 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 RUS70761.1 - 7.4e-25 86.7 9.1 4.6e-09 36.4 0.2 5.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 RUS70761.1 - 0.062 13.7 1.1 0.82 10.0 0.3 2.5 2 1 0 2 2 2 0 Phage T7 capsid assembly protein UreD PF01774.17 RUS70764.1 - 6.8e-37 127.4 0.0 8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Reprolysin_2 PF13574.6 RUS70765.1 - 6.2e-14 52.3 0.1 1.2e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS70765.1 - 1.1e-11 45.3 1.7 3.8e-11 43.5 0.2 2.4 1 1 1 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 RUS70765.1 - 7.2e-10 39.5 16.1 7.2e-10 39.5 16.1 3.7 2 1 0 2 2 2 1 Disintegrin Pep_M12B_propep PF01562.19 RUS70765.1 - 4.8e-08 33.3 0.4 1.7e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 RUS70765.1 - 2.5e-07 30.6 0.1 4.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS70765.1 - 6.2e-05 23.0 0.1 0.0003 20.8 0.0 2.1 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 RUS70765.1 - 0.00022 21.8 1.0 0.00051 20.6 0.9 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Ras PF00071.22 RUS70766.1 - 8.6e-43 145.7 0.2 1e-42 145.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70766.1 - 7.2e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS70766.1 - 2.6e-14 53.1 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Reprolysin_2 PF13574.6 RUS70767.1 - 1.8e-20 73.7 1.0 3.6e-20 72.7 1.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS70767.1 - 1.4e-19 71.0 2.6 3.2e-19 69.9 2.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 RUS70767.1 - 2.2e-10 41.2 16.5 2.2e-10 41.2 16.5 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 RUS70767.1 - 3.2e-09 37.4 1.1 6.1e-09 36.4 1.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS70767.1 - 4.8e-08 33.3 0.4 2.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 RUS70767.1 - 2.9e-07 30.6 0.2 1.2e-06 28.6 0.2 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 RUS70767.1 - 3e-07 30.3 0.2 4.9e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 RUS70767.1 - 0.096 11.6 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 PSD2 PF07624.11 RUS70767.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Innexin PF00876.18 RUS70768.1 - 1.7e-09 37.5 1.7 2e-07 30.7 1.0 2.3 2 0 0 2 2 2 2 Innexin DnaJ PF00226.31 RUS70769.1 - 1e-18 67.2 0.3 1.8e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain CDC27 PF09507.10 RUS70770.1 - 0.35 10.2 44.1 0.61 9.4 44.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_7 PF13499.6 RUS70771.1 - 5.3e-30 103.7 0.5 4.6e-14 52.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS70771.1 - 4.5e-29 97.8 4.3 5.4e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RUS70771.1 - 7.6e-26 87.8 2.8 3.3e-08 32.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS70771.1 - 5.8e-21 73.0 5.3 1.9e-05 23.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RUS70771.1 - 5.7e-19 67.7 4.4 2.9e-06 27.0 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 RUS70771.1 - 5.2e-10 39.5 0.1 9.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS70771.1 - 0.00022 21.5 0.0 0.84 10.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS70771.1 - 0.00028 20.8 0.9 0.68 9.9 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 RUS70771.1 - 0.0017 18.1 1.0 0.049 13.5 0.1 3.1 3 1 1 4 4 4 1 EF hand FGAR-AT_linker PF18072.1 RUS70771.1 - 0.0046 17.5 0.1 9.7 6.8 0.0 3.2 3 0 0 3 3 3 1 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_11 PF08976.11 RUS70771.1 - 0.074 13.9 0.0 7.5 7.5 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain UPF0154 PF03672.13 RUS70771.1 - 0.11 12.5 0.0 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SurA_N_3 PF13624.6 RUS70771.1 - 0.11 12.3 0.2 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 SurA N-terminal domain zf-BED PF02892.15 RUS70772.1 - 0.18 11.9 1.8 2.3 8.3 0.1 2.9 3 0 0 3 3 3 0 BED zinc finger cEGF PF12662.7 RUS70772.1 - 0.23 11.5 0.2 0.23 11.5 0.2 4.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like SWIM PF04434.17 RUS70772.1 - 0.36 10.5 0.1 0.36 10.5 0.1 3.2 4 0 0 4 4 4 0 SWIM zinc finger Neur_chan_LBD PF02931.23 RUS70773.1 - 1.5e-52 178.1 0.5 2.2e-52 177.7 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS70773.1 - 2e-29 103.4 1.1 4.8e-29 102.1 1.1 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4528 PF15031.6 RUS70774.1 - 5.1e-57 191.4 0.1 5.7e-57 191.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4528) Spindle_Spc25 PF08234.12 RUS70774.1 - 0.051 13.8 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 BTB PF00651.31 RUS70775.1 - 1e-17 64.4 0.7 3.2e-16 59.5 0.2 2.5 2 0 0 2 2 2 2 BTB/POZ domain 7tm_1 PF00001.21 RUS70776.1 - 4.5e-17 62.2 9.2 4.5e-17 62.2 9.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS70776.1 - 0.0052 16.2 7.2 0.0064 15.9 7.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF373 PF04123.13 RUS70776.1 - 0.17 11.3 1.9 0.19 11.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pox_A9 PF04835.12 RUS70776.1 - 9.2 6.5 8.9 0.32 11.2 2.5 1.9 2 0 0 2 2 2 0 A9 protein conserved region GLTSCR1 PF15249.6 RUS70777.1 - 2.8e-14 53.4 4.0 2.8e-14 53.4 4.0 3.5 3 0 0 3 3 3 1 Conserved region of unknown function on GLTSCR protein Oxysterol_BP PF01237.18 RUS70779.1 - 6.2e-134 446.5 1.8 7.5e-134 446.2 1.8 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein OSTMP1 PF09777.9 RUS70781.1 - 3.2e-41 141.3 8.8 4e-41 140.9 8.8 1.1 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor MSSP PF03940.13 RUS70782.1 - 0.0027 17.3 17.4 3.2e+03 -2.2 17.4 4.1 1 1 0 1 1 1 0 Male specific sperm protein Prokineticin PF06607.11 RUS70782.1 - 5.1 7.5 16.4 21 5.5 1.2 3.4 1 1 2 3 3 3 0 Prokineticin TPR_1 PF00515.28 RUS70783.1 - 5.9e-18 63.9 0.2 0.0026 17.5 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS70783.1 - 1.3e-14 53.0 2.4 0.00048 20.0 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS70783.1 - 6.2e-12 44.7 0.1 0.013 15.6 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS70783.1 - 1.5e-10 40.6 0.1 0.011 15.4 0.0 4.3 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 RUS70783.1 - 1.6e-10 40.9 8.2 0.0069 17.1 0.1 4.9 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS70783.1 - 2.7e-09 37.4 1.4 0.017 15.6 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70783.1 - 4.6e-09 36.4 1.7 0.15 12.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS70783.1 - 3.7e-08 33.2 1.7 0.89 10.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS70783.1 - 1.9e-07 30.6 3.3 1.3 9.2 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS70783.1 - 2.4e-07 31.3 7.6 0.00021 21.9 0.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS70783.1 - 0.00056 19.7 2.1 1.2 9.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS70783.1 - 0.0015 18.7 1.8 0.16 12.1 0.1 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS70783.1 - 0.0019 18.4 0.9 0.033 14.4 0.0 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RUS70783.1 - 0.002 18.6 0.4 2.5 8.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 RUS70783.1 - 0.0025 17.8 0.2 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 RUS70783.1 - 0.014 15.7 0.5 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS70783.1 - 0.019 14.2 4.5 0.098 11.8 0.4 2.8 2 2 1 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 RUS70783.1 - 0.022 14.5 0.2 0.12 12.0 0.1 2.1 2 1 0 3 3 3 0 26S proteasome subunit RPN7 MAS20 PF02064.15 RUS70783.1 - 0.059 13.5 0.0 4.8 7.3 0.0 2.5 1 1 1 2 2 2 0 MAS20 protein import receptor 14-3-3 PF00244.20 RUS70784.1 - 6.8e-94 313.5 9.5 8e-94 313.3 9.5 1.0 1 0 0 1 1 1 1 14-3-3 protein UPF0160 PF03690.13 RUS70784.1 - 0.0092 15.7 0.2 0.024 14.3 0.2 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0160) Mhr1 PF12829.7 RUS70784.1 - 0.14 12.3 0.3 24 5.1 0.1 2.7 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination TTL PF03133.15 RUS70785.1 - 2.4e-87 292.8 1.0 4.3e-87 292.0 1.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS70785.1 - 9.7e-08 31.6 0.0 0.0019 17.5 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS70785.1 - 0.00049 19.4 0.0 0.091 12.0 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 RUS70785.1 - 0.015 14.9 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RUS70785.1 - 0.04 14.0 0.0 6.5 6.8 0.0 3.4 4 0 0 4 4 4 0 ATP-grasp domain PH_14 PF17787.1 RUS70786.1 - 6.3e-11 42.3 0.0 6.7e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 PH domain PI-PLC-X PF00388.19 RUS70787.1 - 1.6e-58 196.5 0.0 2.5e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RUS70787.1 - 1.8e-43 147.5 0.5 3.9e-43 146.5 0.5 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 RUS70787.1 - 0.0002 21.7 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Fumble PF03630.14 RUS70788.1 - 7.6e-112 373.7 0.1 9.6e-112 373.4 0.1 1.0 1 0 0 1 1 1 1 Fumble Homeodomain PF00046.29 RUS70789.1 - 1.4e-11 44.0 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain DUF1388 PF07142.12 RUS70789.1 - 0.0063 16.4 10.6 0.34 10.9 3.4 4.5 3 1 0 3 3 3 2 Repeat of unknown function (DUF1388) Homez PF11569.8 RUS70789.1 - 0.036 13.5 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ank_2 PF12796.7 RUS70790.1 - 5.7e-23 81.3 0.1 6.5e-09 36.3 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS70790.1 - 7.4e-20 71.1 0.7 2e-06 28.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS70790.1 - 4.3e-14 52.4 4.0 2.3e-06 27.8 0.2 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS70790.1 - 3.2e-13 49.5 5.0 0.048 14.1 0.2 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 RUS70790.1 - 3.8e-13 48.3 0.3 0.031 14.8 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat PSA_CBD PF18341.1 RUS70790.1 - 0.12 12.5 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Paramyxo_ncap PF00973.19 RUS70790.1 - 0.26 10.2 1.9 0.44 9.4 1.9 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SDF PF00375.18 RUS70791.1 - 8.5e-95 318.0 17.6 1e-94 317.8 17.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Laminin_EGF PF00053.24 RUS70792.1 - 0.00031 20.8 61.3 3.3 7.9 19.0 4.6 1 1 3 4 4 4 3 Laminin EGF domain DSL PF01414.19 RUS70792.1 - 0.94 9.8 56.0 0.11 12.8 9.4 3.8 3 1 0 3 3 3 0 Delta serrate ligand YqzH PF14164.6 RUS70793.1 - 0.11 12.5 0.4 0.19 11.8 0.4 1.3 1 0 0 1 1 1 0 YqzH-like protein Pkinase_Tyr PF07714.17 RUS70794.1 - 3.3e-54 183.9 0.0 7.8e-54 182.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS70794.1 - 1.8e-18 66.9 0.1 8.7e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DnaJ PF00226.31 RUS70795.1 - 1.2e-19 70.2 0.1 2.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1601 PF07671.11 RUS70795.1 - 1.7 8.6 5.7 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) EF-hand_6 PF13405.6 RUS70796.1 - 3.2e-13 48.5 9.8 7.4e-08 31.7 0.9 3.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 RUS70796.1 - 2e-12 45.7 11.2 1.2e-07 30.7 1.6 4.2 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 RUS70796.1 - 7e-12 45.6 5.2 3.9e-06 27.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS70796.1 - 3.1e-08 32.7 3.4 1.7e-05 24.1 1.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS70796.1 - 3.1e-06 26.9 11.7 0.021 14.7 0.8 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 RUS70796.1 - 0.0047 17.2 0.0 4.3 7.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 RUS70796.1 - 0.013 15.5 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RUS70796.1 - 0.015 16.1 0.1 0.13 13.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS70796.1 - 0.047 14.0 0.4 0.14 12.5 0.2 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Syntaxin PF00804.25 RUS70796.1 - 0.068 12.8 0.2 7.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Syntaxin HMA PF00403.26 RUS70797.1 - 0.0015 18.9 0.1 0.0035 17.8 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF229 PF02995.17 RUS70798.1 - 3.3e-98 329.5 0.0 5.5e-98 328.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RUS70798.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS70798.1 - 0.0017 17.8 8.1 0.011 15.2 0.1 2.5 2 1 1 3 3 3 2 Sulfatase DUF1501 PF07394.12 RUS70798.1 - 0.074 12.1 0.5 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF5012 PF16404.5 RUS70798.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) DUF3915 PF13054.6 RUS70798.1 - 0.74 9.8 14.1 1.7 8.6 14.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Mucin PF01456.17 RUS70798.1 - 4.6 7.2 7.7 10 6.1 7.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein CCDC144C PF14915.6 RUS70799.1 - 0.0038 16.4 4.1 0.0038 16.4 4.1 1.6 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region Filament PF00038.21 RUS70799.1 - 0.0072 15.9 1.8 0.0072 15.9 1.8 2.2 1 1 1 2 2 2 1 Intermediate filament protein DUF3450 PF11932.8 RUS70799.1 - 0.024 14.0 6.9 0.21 10.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 RUS70799.1 - 0.075 13.1 9.3 0.078 13.0 5.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5407 PF17401.2 RUS70799.1 - 0.087 13.1 2.0 18 5.7 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5407) NRN1 PF15056.6 RUS70799.1 - 0.14 12.3 1.9 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Neuritin protein family PI_PP_I PF18363.1 RUS70799.1 - 0.24 11.6 2.5 0.94 9.7 0.1 2.5 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain TMF_TATA_bd PF12325.8 RUS70799.1 - 0.52 10.6 9.7 1.4 9.2 7.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 RUS70799.1 - 1 9.2 10.3 0.26 11.1 0.8 3.2 2 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 RUS70799.1 - 3.8 7.6 13.2 61 3.7 10.0 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 RUS70799.1 - 7.7 7.2 6.5 60 4.4 3.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA UTP15_C PF09384.10 RUS70801.1 - 2.4e-40 137.6 0.0 3.6e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal LSDAT_euk PF18139.1 RUS70802.1 - 7.8e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 SLOG in TRPM WcbI PF18588.1 RUS70805.1 - 0.008 15.8 0.8 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis enzyme WcbI TORC_M PF12885.7 RUS70806.1 - 1.9e-23 83.2 7.3 1.9e-23 83.2 7.3 4.2 3 2 0 4 4 4 1 Transducer of regulated CREB activity middle domain TORC_N PF12884.7 RUS70806.1 - 7.4e-21 74.7 0.1 7.4e-21 74.7 0.1 5.1 5 0 0 5 5 5 1 Transducer of regulated CREB activity, N terminus Vicilin_N PF04702.12 RUS70806.1 - 0.016 15.1 1.0 0.016 15.1 1.0 2.3 2 0 0 2 2 2 0 Vicilin N terminal region RVT_1 PF00078.27 RUS70807.1 - 9.2e-05 22.1 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MM_CoA_mutase PF01642.22 RUS70809.1 - 5.6e-237 787.3 0.2 6.6e-237 787.1 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 RUS70809.1 - 4.1e-15 55.9 0.2 1.2e-14 54.3 0.2 1.9 1 0 0 1 1 1 1 B12 binding domain TIR_2 PF13676.6 RUS70810.1 - 0.0026 18.4 0.0 0.008 16.8 0.0 1.8 2 0 0 2 2 2 1 TIR domain Barwin PF00967.17 RUS70810.1 - 0.071 13.0 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Barwin family TIR_2 PF13676.6 RUS70811.1 - 4.8e-14 53.0 0.0 8.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS70811.1 - 0.045 13.6 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain DUF4062 PF13271.6 RUS70811.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Flavi_M PF01004.19 RUS70812.1 - 0.023 14.4 0.1 0.023 14.4 0.1 2.2 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M ATG27 PF09451.10 RUS70814.1 - 7.5e-16 58.8 0.0 2.6e-14 53.7 0.0 2.0 1 1 1 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 RUS70814.1 - 8e-14 51.3 0.7 3e-13 49.5 0.7 2.0 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ECSCR PF15820.5 RUS70814.1 - 0.014 15.2 1.2 0.053 13.3 0.6 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Polyketide_cyc PF03364.20 RUS70816.1 - 0.069 13.4 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF913 PF06025.12 RUS70816.1 - 0.8 8.6 3.8 1.2 8.0 3.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MACPF PF01823.19 RUS70817.1 - 1.5e-18 67.7 0.0 2.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain zf-UBR PF02207.20 RUS70818.1 - 1e-19 70.4 9.6 3.7e-19 68.6 9.6 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Stc1 PF12898.7 RUS70818.1 - 3.1 8.4 7.3 0.51 10.9 0.3 3.0 3 0 0 3 3 3 0 Stc1 domain IBR PF01485.21 RUS70819.1 - 2.3e-21 75.8 37.3 7.6e-09 35.7 6.8 3.2 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 RUS70819.1 - 3.6 7.8 37.9 0.16 12.1 10.5 3.4 3 0 0 3 3 3 0 Piccolo Zn-finger C2 PF00168.30 RUS70820.1 - 1.2e-20 73.7 0.0 8.5e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 RUS70820.1 - 5.6e-16 58.8 9.9 5.6e-16 58.8 9.9 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger PDZ_6 PF17820.1 RUS70820.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 RUS70820.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-piccolo PF05715.13 RUS70820.1 - 0.095 12.9 10.1 0.24 11.6 10.1 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger PHD PF00628.29 RUS70820.1 - 1.6 8.7 11.4 3.6 7.6 11.4 1.6 1 0 0 1 1 1 0 PHD-finger adh_short PF00106.25 RUS70821.1 - 3.5e-34 118.0 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS70821.1 - 1e-20 74.3 0.0 1.5e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 RUS70821.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) BCA_ABC_TP_C PF12399.8 RUS70821.1 - 0.19 11.7 0.4 0.53 10.3 0.4 1.8 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-RanBP PF00641.18 RUS70823.1 - 5.3e-07 28.8 1.3 1.4e-06 27.5 1.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Trimer_CC PF08954.11 RUS70823.1 - 0.084 12.4 0.5 0.79 9.3 0.0 2.5 2 0 0 2 2 2 0 Trimerisation motif TMF_DNA_bd PF12329.8 RUS70823.1 - 0.17 11.9 0.3 0.54 10.3 0.3 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 RUS70823.1 - 7.3 6.8 6.6 1.3 9.2 2.4 1.9 2 0 0 2 2 2 0 bZIP transcription factor Hormone_recep PF00104.30 RUS70824.1 - 1.9e-26 92.9 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Abhydrolase_5 PF12695.7 RUS70826.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kin17_mid PF10357.9 RUS70827.1 - 1.8e-50 170.0 2.3 1.8e-50 170.0 2.3 2.8 3 1 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 RUS70827.1 - 9.5e-23 80.1 6.0 2e-22 79.1 6.0 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 RUS70827.1 - 0.00062 20.1 6.2 0.0016 18.8 6.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS70827.1 - 0.00065 19.9 5.6 0.002 18.4 5.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding KOW PF00467.29 RUS70827.1 - 0.0026 17.7 3.4 0.0037 17.2 0.0 2.8 2 1 0 2 2 2 1 KOW motif zf-C2H2_2 PF12756.7 RUS70827.1 - 0.018 15.4 1.1 0.018 15.4 1.1 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Seryl_tRNA_N PF02403.22 RUS70827.1 - 0.025 14.8 3.3 0.025 14.8 3.3 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mhr1 PF12829.7 RUS70827.1 - 0.076 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination TetR_C_19 PF17924.1 RUS70827.1 - 0.18 12.4 2.7 0.21 12.2 0.3 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Adaptin_N PF01602.20 RUS70828.1 - 5.2e-58 196.9 6.5 1.2e-57 195.7 6.5 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 RUS70828.1 - 4e-06 27.2 9.7 0.029 14.9 0.0 5.8 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 RUS70828.1 - 1.6e-05 24.7 1.3 0.025 14.8 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 RUS70828.1 - 0.00039 20.7 0.2 0.12 12.8 0.0 3.4 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 RUS70828.1 - 0.0012 19.0 1.0 0.13 12.3 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RUS70828.1 - 0.017 15.1 1.2 0.77 9.9 0.2 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Proho_convert PF12177.8 RUS70828.1 - 0.095 12.7 0.2 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 Prohormone convertase enzyme TraB PF01963.17 RUS70829.1 - 5.7e-30 105.1 0.0 8.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 TraB family zf-C2H2_aberr PF17017.5 RUS70829.1 - 0.17 12.0 0.3 0.29 11.2 0.3 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger SDA1 PF05285.12 RUS70829.1 - 2.4 7.5 6.7 3 7.2 6.7 1.2 1 0 0 1 1 1 0 SDA1 RNase_T PF00929.24 RUS70830.1 - 7.8e-17 62.3 0.0 1.4e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 RUS70830.1 - 0.011 15.5 0.0 0.05 13.3 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease GTP_EFTU PF00009.27 RUS70831.1 - 5.3e-59 199.0 0.7 7.9e-59 198.5 0.7 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RUS70831.1 - 2.3e-14 53.5 2.1 4.9e-14 52.5 2.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 RUS70831.1 - 1.5e-09 38.1 0.0 4.6e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 RUS70831.1 - 0.00014 21.9 0.1 0.00029 20.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 RUS70831.1 - 0.057 13.9 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 RUS70831.1 - 0.063 12.9 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 RUS70831.1 - 0.095 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 RUS70832.1 - 5.4e-40 137.0 0.0 1e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.7 RUS70832.1 - 7.1e-20 70.8 31.6 7.5e-08 32.6 1.5 5.7 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS70832.1 - 3.5e-17 62.4 14.8 1.4e-13 50.7 6.8 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 RUS70832.1 - 6.4e-14 51.5 27.2 8.3e-06 25.5 6.6 4.6 1 1 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RUS70832.1 - 5.3e-05 22.9 21.9 0.13 12.3 0.1 8.6 9 0 0 9 9 9 2 Leucine Rich repeat AAA_33 PF13671.6 RUS70832.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain LRR_1 PF00560.33 RUS70832.1 - 1.3 9.8 29.1 15 6.6 0.1 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat Death PF00531.22 RUS70833.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Death domain DUF4128 PF13554.6 RUS70833.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Peptidase_M24 PF00557.24 RUS70835.1 - 3.6e-42 144.4 0.1 4.9e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.14 RUS70835.1 - 0.31 9.3 7.6 0.58 8.4 7.6 1.4 1 1 0 1 1 1 0 CDC45-like protein DUF3506 PF12014.8 RUS70835.1 - 0.49 10.4 3.9 0.52 10.3 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Macoilin PF09726.9 RUS70835.1 - 0.88 8.1 5.6 1.3 7.5 5.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF4710 PF15828.5 RUS70835.1 - 2.7 8.2 16.9 3.8 7.7 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) WASH_WAHD PF11945.8 RUS70836.1 - 1.4e-89 300.5 0.1 1.8e-89 300.1 0.1 1.0 1 0 0 1 1 1 1 WAHD domain of WASH complex AcetDehyd-dimer PF09290.11 RUS70837.1 - 0.005 17.0 0.1 0.014 15.6 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Macoilin PF09726.9 RUS70837.1 - 2.3 6.7 12.9 2.9 6.3 12.9 1.2 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 RUS70837.1 - 5 5.7 18.5 6.9 5.2 18.5 1.1 1 0 0 1 1 1 0 Hamartin protein LLGL PF08366.13 RUS70838.1 - 1e-34 119.0 0.0 3.5e-34 117.3 0.0 2.0 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 RUS70838.1 - 2.2e-06 26.6 0.0 9.8e-06 24.5 0.0 2.2 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 RUS70838.1 - 3.5e-06 27.2 1.2 0.14 12.5 0.1 5.2 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 RUS70838.1 - 2.6e-05 24.1 2.6 0.17 11.6 0.0 5.0 3 1 3 6 6 6 1 TUP1-like enhancer of split Synaptobrevin PF00957.21 RUS70838.1 - 0.0042 16.8 0.6 0.0042 16.8 0.6 2.5 2 0 0 2 2 2 1 Synaptobrevin Hydrolase_4 PF12146.8 RUS70838.1 - 0.012 14.9 0.0 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 WD40_like PF17005.5 RUS70838.1 - 0.013 14.8 0.0 0.043 13.1 0.0 1.8 1 1 0 1 1 1 0 WD40-like domain DUF2442 PF10387.9 RUS70838.1 - 0.082 13.2 0.0 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) WD40 PF00400.32 RUS70838.1 - 0.28 12.1 3.9 31 5.7 0.1 4.8 4 1 0 4 4 4 0 WD domain, G-beta repeat IQ PF00612.27 RUS70839.1 - 0.00028 20.4 0.4 0.00076 19.1 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif FokI_N PF02981.15 RUS70839.1 - 0.017 15.3 0.1 0.033 14.4 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Insulin PF00049.18 RUS70840.1 - 4.7e-07 30.7 5.8 1.5e-06 29.1 5.8 1.8 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Jas PF16135.5 RUS70840.1 - 0.032 14.4 0.3 0.043 14.0 0.3 1.3 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Ins_beta PF03488.14 RUS70840.1 - 0.058 13.4 9.7 0.58 10.2 0.2 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type MRP-S28 PF10213.9 RUS70841.1 - 1.8e-13 51.0 0.0 4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein GAS PF13851.6 RUS70842.1 - 0.23 10.8 22.2 0.33 10.3 6.9 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DHC PF09626.10 RUS70842.1 - 0.43 11.5 4.4 12 6.8 0.3 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c V_ATPase_I PF01496.19 RUS70842.1 - 5.8 4.7 10.2 6.3 4.6 9.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 RUS70842.1 - 8.8 6.4 8.3 8.7 6.4 2.2 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 RUS70842.1 - 9.8 4.9 8.3 11 4.8 7.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Pkinase_Tyr PF07714.17 RUS70843.1 - 6.2e-99 330.5 0.0 1.1e-98 329.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS70843.1 - 4.6e-41 140.9 0.0 6.1e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 RUS70843.1 - 9.5e-38 128.2 1.8 2.4e-12 46.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS70843.1 - 2.4e-34 117.7 3.4 2.8e-10 40.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS70843.1 - 7.8e-24 83.8 5.3 3e-07 30.7 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS70843.1 - 1e-22 80.1 3.1 2.3e-06 27.7 0.5 3.8 4 0 0 4 4 3 3 Immunoglobulin domain V-set PF07686.17 RUS70843.1 - 1.5e-15 57.3 2.3 2.1e-07 31.1 0.1 4.0 3 1 1 4 4 4 3 Immunoglobulin V-set domain C2-set PF05790.15 RUS70843.1 - 8.8e-07 29.0 0.1 0.024 14.8 0.0 4.3 4 1 1 5 5 5 2 Immunoglobulin C2-set domain Ig_6 PF18452.1 RUS70843.1 - 2.7e-06 26.8 0.1 0.077 12.6 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 RUS70843.1 - 8.7e-06 25.7 0.1 0.61 10.2 0.0 3.8 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS70843.1 - 2.3e-05 24.7 1.3 0.27 11.6 0.1 3.5 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Ig_4 PF16680.5 RUS70843.1 - 2.7e-05 24.3 0.4 1.2 9.4 0.0 3.7 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 RUS70843.1 - 0.00017 21.6 0.0 0.034 14.2 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 RUS70843.1 - 0.0027 17.7 3.7 0.29 11.1 0.0 3.4 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 RUS70843.1 - 0.0083 15.9 4.2 0.42 10.4 0.2 3.2 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Kinase-like PF14531.6 RUS70843.1 - 0.049 12.9 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like HTH_32 PF13565.6 RUS70844.1 - 0.00018 22.1 0.0 0.00032 21.3 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 RUS70844.1 - 0.00058 19.9 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 RUS70844.1 - 0.0013 18.9 0.1 0.0023 18.2 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 RUS70844.1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF977 PF06163.11 RUS70844.1 - 0.0075 16.2 0.1 0.0097 15.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) PCI PF01399.27 RUS70844.1 - 0.0078 16.7 0.0 0.011 16.2 0.0 1.3 1 1 0 1 1 1 1 PCI domain HTH_23 PF13384.6 RUS70844.1 - 0.015 15.1 1.1 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain DUF4817 PF16087.5 RUS70844.1 - 0.018 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS70844.1 - 0.037 14.4 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS70844.1 - 0.052 13.0 0.1 0.095 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 RUS70844.1 - 0.055 13.5 0.0 4.8 7.3 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 RUS70844.1 - 0.079 13.1 0.0 6.8 6.9 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 RUS70844.1 - 0.1 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TUSC2 PF15000.6 RUS70845.1 - 5.8e-28 97.4 0.0 6.9e-28 97.2 0.0 1.2 1 1 0 1 1 1 1 Tumour suppressor candidate 2 TPT PF03151.16 RUS70846.1 - 7.7e-21 74.7 19.7 9.6e-21 74.4 19.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS70846.1 - 3.4e-10 40.2 33.0 3.8e-07 30.4 12.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family Phage_holin_2_3 PF16080.5 RUS70846.1 - 0.073 12.8 1.2 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 K1 PF02960.14 RUS70846.1 - 1.7 8.7 5.8 0.63 10.2 0.1 2.6 2 1 1 3 3 3 0 K1 glycoprotein DUF4097 PF13349.6 RUS70847.1 - 2.6e-12 46.6 9.9 3e-06 26.8 3.4 3.1 1 1 2 3 3 3 3 Putative adhesin V_ATPase_I PF01496.19 RUS70849.1 - 2.9e-294 978.1 29.7 6.9e-231 768.5 6.3 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 RUS70849.1 - 1.5 9.6 3.8 42 4.9 0.9 2.8 2 0 0 2 2 2 0 Occludin homology domain SHMT PF00464.19 RUS70850.1 - 4.7e-179 595.1 0.4 8.9e-134 446.0 0.2 2.0 1 1 1 2 2 2 2 Serine hydroxymethyltransferase Nif11 PF07862.11 RUS70850.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Nif11 domain Ribosomal_L14 PF00238.19 RUS70851.1 - 1.2e-34 119.0 0.0 1.6e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Gal-3-0_sulfotr PF06990.11 RUS70852.1 - 9e-57 192.8 2.5 1.2e-56 192.3 2.5 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Isochorismatase PF00857.20 RUS70854.1 - 1.5e-26 93.7 0.0 2e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family SLX9 PF15341.6 RUS70855.1 - 4e-14 53.1 14.4 4e-14 53.1 14.4 1.8 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 RPN2_C PF18004.1 RUS70855.1 - 0.0088 16.0 6.8 0.0088 16.0 6.8 1.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5407 PF17401.2 RUS70855.1 - 0.017 15.3 0.1 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5407) HV_small_capsid PF17086.5 RUS70855.1 - 2 8.8 5.4 0.36 11.1 0.5 2.3 1 1 2 3 3 3 0 Small capsid protein of Herpesviridae ARD PF03079.14 RUS70855.1 - 5.8 7.1 8.1 0.41 10.8 2.2 2.0 2 1 1 3 3 3 0 ARD/ARD' family FKBP_C PF00254.28 RUS70856.1 - 4.7e-32 110.2 0.0 6.9e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 RUS70856.1 - 3.1e-08 33.9 3.6 5.6e-08 33.1 3.6 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS70856.1 - 8.1e-08 31.3 2.7 0.0013 18.2 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS70856.1 - 1.4e-05 24.6 2.2 0.042 13.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS70856.1 - 0.0016 18.3 0.3 0.45 10.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS70856.1 - 0.0039 16.6 2.1 0.11 12.0 0.4 2.5 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 RUS70856.1 - 0.0092 16.3 2.5 0.084 13.2 2.5 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FKBP_C PF00254.28 RUS70857.1 - 2.7e-31 107.8 0.0 4e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 RUS70857.1 - 1.3e-09 38.4 1.6 2.6e-09 37.4 1.6 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS70857.1 - 1.7e-07 30.3 6.5 0.00043 19.6 2.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS70857.1 - 2e-06 27.3 4.8 0.016 15.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS70857.1 - 0.00042 19.7 7.7 0.016 14.7 2.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS70857.1 - 0.0013 18.5 0.2 0.029 14.2 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS70857.1 - 0.011 16.0 3.4 0.82 10.0 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RUS70857.1 - 0.23 11.3 2.3 14 5.7 0.1 2.3 2 0 0 2 2 2 0 EF hand SSF PF00474.17 RUS70858.1 - 1e-08 34.5 0.2 1.4e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4282 PF14110.6 RUS70858.1 - 0.18 12.6 0.4 0.18 12.6 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) CTP_transf_like PF01467.26 RUS70859.1 - 5.4e-25 88.3 0.0 7.4e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like DUF371 PF04027.13 RUS70859.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF371) SSF PF00474.17 RUS70860.1 - 2e-18 66.5 22.6 7.6e-07 28.3 5.2 3.1 2 1 1 3 3 3 3 Sodium:solute symporter family Cytochrome_CBB3 PF13442.6 RUS70861.1 - 0.088 13.1 0.0 3.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III 2OG-FeII_Oxy_3 PF13640.6 RUS70863.1 - 3.4e-14 53.5 0.0 6.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P4Ha_N PF08336.11 RUS70863.1 - 1.6e-08 34.6 0.0 6.1e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ubiquitin_4 PF18036.1 RUS70863.1 - 0.066 13.3 0.2 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain 7tm_1 PF00001.21 RUS70864.1 - 5.2e-10 39.1 21.0 6.7e-10 38.7 21.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS70864.1 - 6.3e-08 32.3 26.7 8e-07 28.6 26.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS70864.1 - 2.5e-05 23.8 23.1 4.1e-05 23.1 23.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx HCMV_UL124 PF17609.2 RUS70864.1 - 0.18 12.0 2.3 12 6.2 0.8 2.8 2 1 0 2 2 2 0 Family of unknown function CCSMST1 PF15013.6 RUS70864.1 - 0.2 11.8 0.6 1 9.5 0.3 2.3 2 0 0 2 2 2 0 CCSMST1 family Pkinase PF00069.25 RUS70865.1 - 1.3e-34 119.8 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS70865.1 - 8.6e-21 74.4 0.0 1.1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS70865.1 - 3.5e-09 36.4 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS70865.1 - 0.027 13.9 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS70865.1 - 0.033 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 RUS70867.1 - 1.9e-12 46.3 0.1 2.3e-05 24.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS70867.1 - 1.9e-11 43.3 0.1 7.9e-06 25.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS70867.1 - 6.5e-09 36.2 0.5 0.0066 16.9 0.5 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS70867.1 - 2.4e-08 33.5 0.7 5.7e-06 25.9 0.3 3.4 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 RUS70867.1 - 2.5e-07 30.4 0.1 0.027 14.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS70867.1 - 3.7e-07 30.2 0.1 2.3e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS70867.1 - 6e-07 29.8 0.3 0.0064 17.2 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS70867.1 - 5.9e-06 26.8 0.6 0.0017 19.0 0.2 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70867.1 - 8e-06 26.1 1.4 0.00044 20.5 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS70867.1 - 0.00021 21.4 0.2 0.6 10.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS70867.1 - 0.0019 18.1 0.1 0.54 10.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat S1 PF00575.23 RUS70867.1 - 0.0097 16.2 0.1 0.11 12.8 0.1 2.4 1 1 0 1 1 1 1 S1 RNA binding domain TPR_MalT PF17874.1 RUS70867.1 - 0.015 14.7 2.0 0.026 13.9 2.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Tetraspanin PF00335.20 RUS70868.1 - 7.8e-08 32.3 6.3 1.5e-07 31.4 6.3 1.4 1 1 0 1 1 1 1 Tetraspanin family TMEMspv1-c74-12 PF11044.8 RUS70868.1 - 0.21 11.6 0.6 0.62 10.1 0.6 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TctB PF07331.11 RUS70868.1 - 0.63 10.3 5.8 17 5.6 0.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TRAP_alpha PF03896.16 RUS70869.1 - 3.1 6.9 4.9 1.1 8.5 2.3 1.5 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.7 RUS70869.1 - 6.3 6.6 7.2 9.4 6.0 7.2 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein Rep_N PF08724.10 RUS70871.1 - 0.00055 19.7 6.1 6.5 6.5 0.1 3.7 1 1 4 5 5 5 5 Rep protein catalytic domain like eIF3_p135 PF12807.7 RUS70871.1 - 0.065 13.3 4.2 12 5.8 0.9 3.4 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 PKD_channel PF08016.12 RUS70872.1 - 1.1e-31 110.0 10.3 1.1e-31 110.0 10.3 1.9 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 RUS70872.1 - 2.4e-05 24.9 0.0 6.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 PLAT/LH2 domain Peptidase_C16 PF01831.17 RUS70872.1 - 0.0052 16.6 0.5 0.01 15.6 0.5 1.4 1 0 0 1 1 1 1 Peptidase C16 family Sid-5 PF17204.3 RUS70872.1 - 0.087 13.0 0.1 0.37 11.0 0.1 2.1 1 0 0 1 1 1 0 Sid-5 family 7tm_1 PF00001.21 RUS70873.1 - 0.003 16.9 5.3 0.073 12.4 0.9 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS70873.1 - 0.005 16.2 3.8 0.045 13.0 0.0 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS70874.1 - 6.9e-10 38.7 20.1 1e-09 38.1 20.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS70874.1 - 4e-07 29.9 17.8 4e-07 29.9 17.8 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 RUS70874.1 - 0.0004 20.1 24.9 0.0004 20.1 24.9 2.5 1 1 0 2 2 2 1 Srg family chemoreceptor Ion_trans_2 PF07885.16 RUS70876.1 - 5.2e-15 55.2 19.1 6.2e-14 51.7 5.6 2.9 2 1 1 3 3 2 2 Ion channel BUD22 PF09073.10 RUS70876.1 - 0.00011 21.7 19.3 0.00017 21.1 19.3 1.2 1 0 0 1 1 1 1 BUD22 Sec62 PF03839.16 RUS70876.1 - 0.00023 20.8 7.3 0.00047 19.7 7.3 1.5 1 0 0 1 1 1 1 Translocation protein Sec62 RPOL_N PF14700.6 RUS70876.1 - 0.0046 16.4 8.4 0.0066 15.9 8.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Pox_Ag35 PF03286.14 RUS70876.1 - 0.0082 16.0 17.8 0.013 15.3 17.8 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Serinc PF03348.15 RUS70876.1 - 0.0089 15.0 1.7 0.023 13.6 1.7 1.7 1 0 0 1 1 1 1 Serine incorporator (Serinc) GAGA_bind PF06217.12 RUS70876.1 - 0.011 16.0 13.2 0.018 15.4 13.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.14 RUS70876.1 - 0.012 16.1 9.6 0.023 15.2 9.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 AAA_23 PF13476.6 RUS70876.1 - 0.014 15.9 10.4 0.026 15.0 10.4 1.5 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 RUS70876.1 - 0.015 15.5 1.7 0.023 14.9 1.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 RUS70876.1 - 0.02 13.9 6.1 0.03 13.3 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FancD2 PF14631.6 RUS70876.1 - 0.021 12.3 12.3 0.03 11.8 12.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Protocadherin PF08374.11 RUS70876.1 - 0.034 14.1 8.8 0.065 13.2 8.8 1.4 1 0 0 1 1 1 0 Protocadherin Ploopntkinase2 PF18747.1 RUS70876.1 - 0.066 12.5 5.4 0.11 11.8 5.4 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 SARAF PF06682.12 RUS70876.1 - 0.088 12.4 2.7 0.18 11.4 0.9 2.0 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CwsA PF10814.8 RUS70876.1 - 0.1 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA CENP-B_dimeris PF09026.10 RUS70876.1 - 0.11 12.9 7.0 0.16 12.4 4.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tim54 PF11711.8 RUS70876.1 - 0.13 11.0 12.5 0.23 10.2 12.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 RUS70876.1 - 0.18 9.9 11.9 0.3 9.1 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 RUS70876.1 - 0.18 10.5 14.0 0.29 9.9 14.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 RUS70876.1 - 0.19 10.1 1.9 0.32 9.4 1.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gti1_Pac2 PF09729.9 RUS70876.1 - 0.22 11.6 8.4 0.036 14.1 4.7 1.6 2 0 0 2 2 1 0 Gti1/Pac2 family DUF2151 PF10221.9 RUS70876.1 - 0.28 9.7 12.6 0.39 9.3 12.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Cellulose_synt PF03552.14 RUS70876.1 - 0.31 9.5 4.8 0.47 8.9 4.8 1.2 1 0 0 1 1 1 0 Cellulose synthase V_ATPase_I PF01496.19 RUS70876.1 - 0.32 8.9 12.6 0.54 8.1 12.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 RUS70876.1 - 0.35 10.0 8.2 0.57 9.3 8.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Shisa PF13908.6 RUS70876.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.3 1 1 0 2 2 1 0 Wnt and FGF inhibitory regulator Vma12 PF11712.8 RUS70876.1 - 0.47 10.5 7.6 27 4.8 0.0 2.5 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PA26 PF04636.13 RUS70876.1 - 0.53 9.1 6.3 0.75 8.7 6.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 RUS70876.1 - 0.62 9.9 18.3 1 9.1 18.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 RUS70876.1 - 0.73 7.9 16.6 1.2 7.1 16.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPL5 PF18168.1 RUS70876.1 - 0.84 8.9 9.8 1.4 8.1 9.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 OATP PF03137.20 RUS70876.1 - 0.87 7.8 3.9 1.6 6.9 3.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 RUS70876.1 - 1.1 8.0 6.0 1.6 7.5 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SpoIIP PF07454.11 RUS70876.1 - 1.3 8.4 13.8 2 7.8 13.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4820 PF16091.5 RUS70876.1 - 1.8 7.9 11.6 3.5 6.9 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 RUS70876.1 - 2 7.2 24.0 3.7 6.3 24.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1943 PF09172.11 RUS70876.1 - 2.2 7.5 8.3 3.6 6.7 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Rtf2 PF04641.12 RUS70876.1 - 2.2 7.6 22.0 3.7 6.8 22.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.10 RUS70876.1 - 4.5 7.6 27.2 9.6 6.5 27.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 RUS70876.1 - 5.2 7.0 28.5 9.8 6.1 28.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SSF PF00474.17 RUS70877.1 - 0.06 12.2 1.0 0.063 12.1 1.0 1.2 1 1 0 1 1 1 0 Sodium:solute symporter family zf-RING_2 PF13639.6 RUS70878.1 - 1.4e-06 28.5 9.3 4.4e-06 26.9 9.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 RUS70878.1 - 0.00011 22.2 1.8 0.00027 20.9 1.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 RUS70878.1 - 0.00022 21.3 5.8 0.00022 21.3 5.8 2.2 2 0 0 2 2 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 RUS70878.1 - 0.00096 19.4 7.3 0.00096 19.4 7.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 RUS70878.1 - 0.0043 17.3 3.9 0.016 15.5 3.9 2.0 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 RUS70878.1 - 0.0078 16.1 9.3 0.022 14.6 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 RUS70878.1 - 0.0094 16.1 7.9 0.026 14.7 7.9 1.8 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 RUS70878.1 - 0.02 14.5 5.1 0.06 13.0 5.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 RUS70878.1 - 0.059 13.2 9.1 0.2 11.5 9.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 RUS70878.1 - 0.15 12.0 5.5 0.35 10.8 5.5 1.7 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 RUS70878.1 - 0.15 12.2 4.2 0.62 10.2 4.3 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 RUS70878.1 - 0.75 9.7 7.8 0.24 11.3 3.9 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.6 RUS70878.1 - 5.7 6.9 8.4 26 4.8 8.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyr_redox_2 PF07992.14 RUS70879.1 - 3.2e-09 36.4 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GATase_2 PF00310.21 RUS70880.1 - 3.2e-169 563.1 0.0 4.2e-169 562.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 RUS70880.1 - 2.8e-155 517.0 0.2 4.7e-154 513.0 0.1 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RUS70880.1 - 3.3e-112 374.5 0.0 2.3e-110 368.5 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 RUS70880.1 - 8.4e-80 266.9 0.1 1.5e-79 266.0 0.1 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 RUS70880.1 - 1.4e-21 77.0 0.2 9.2e-15 54.6 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 RUS70880.1 - 6.6e-21 74.2 0.2 1.9e-20 72.7 0.0 1.9 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 RUS70880.1 - 4.9e-10 39.5 0.0 1.9e-09 37.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RUS70880.1 - 3.2e-09 37.2 2.2 1.1e-06 29.1 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RUS70880.1 - 3.2e-06 27.0 0.2 0.00011 21.9 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 RUS70880.1 - 3.8e-06 26.5 0.0 7.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 RUS70880.1 - 1.3e-05 24.1 1.5 1.3e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 RUS70880.1 - 1.4e-05 24.5 0.1 0.0033 16.7 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RUS70880.1 - 1.6e-05 24.5 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS70880.1 - 0.00029 20.2 0.0 0.0011 18.3 0.0 1.9 1 0 0 1 1 1 1 Thi4 family FMN_dh PF01070.18 RUS70880.1 - 0.00038 19.6 0.6 0.0011 18.1 0.6 1.8 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FAD_binding_2 PF00890.24 RUS70880.1 - 0.00072 18.7 0.1 0.0015 17.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 RUS70880.1 - 0.001 17.6 0.1 0.018 13.5 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 RUS70880.1 - 0.0064 15.8 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 RUS70880.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 RUS70880.1 - 0.024 13.7 0.4 0.46 9.5 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 RUS70880.1 - 0.051 14.0 0.6 5.8 7.4 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 RUS70880.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 RUS70880.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding CD225 PF04505.12 RUS70883.1 - 0.0013 18.8 0.5 0.0013 18.8 0.5 1.6 2 0 0 2 2 2 1 Interferon-induced transmembrane protein Myotub-related PF06602.14 RUS70884.1 - 1.1e-112 376.5 0.0 1.6e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 RUS70884.1 - 3.5e-18 65.5 11.6 3.5e-18 65.5 11.6 2.5 3 0 0 3 3 3 1 FYVE zinc finger Y_phosphatase PF00102.27 RUS70884.1 - 0.0034 17.0 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4681 PF15732.5 RUS70884.1 - 0.026 14.8 0.1 0.08 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) DSPc PF00782.20 RUS70884.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS70884.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family I_LWEQ PF01608.17 RUS70884.1 - 0.15 12.3 3.4 0.66 10.2 0.7 2.4 2 0 0 2 2 2 0 I/LWEQ domain zf_C2HC_14 PF18574.1 RUS70884.1 - 1.5 8.7 6.0 0.39 10.5 2.2 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain IBR PF01485.21 RUS70884.1 - 4.3 7.6 14.3 0.015 15.5 4.2 2.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain NAC PF01849.18 RUS70885.1 - 0.15 12.1 0.4 20 5.2 0.1 2.5 1 1 2 3 3 3 0 NAC domain I-set PF07679.16 RUS70886.1 - 1.1e-19 70.3 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS70886.1 - 1.2e-17 64.2 0.0 1.1e-13 51.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS70886.1 - 1.3e-15 57.3 0.1 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS70886.1 - 5.8e-14 52.2 0.0 3.5e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS70886.1 - 5.5e-06 26.5 0.1 0.096 12.9 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS70886.1 - 2.8e-05 23.6 0.0 0.07 12.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 RUS70886.1 - 3.4e-05 24.2 0.0 0.025 15.0 0.0 2.3 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS70886.1 - 0.00014 22.0 0.0 0.14 12.4 0.0 2.4 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS70886.1 - 0.0004 20.4 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS70886.1 - 0.06 13.4 0.3 3.4 7.8 0.0 2.4 2 1 0 2 2 2 0 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 RUS70886.1 - 0.11 12.2 0.1 0.31 10.9 0.1 1.7 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 DUF4225 PF13988.6 RUS70886.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Ig_3 PF13927.6 RUS70887.1 - 2.2e-13 50.6 1.5 2.9e-11 43.8 0.5 2.8 3 0 0 3 3 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS70887.1 - 7e-12 45.5 0.8 6.2e-09 36.1 0.2 3.0 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS70887.1 - 4.9e-08 32.9 0.1 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 RUS70887.1 - 0.00024 21.2 0.1 0.00086 19.4 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS70887.1 - 0.0022 18.1 0.2 0.048 13.8 0.2 2.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain DNA_pol_phi PF04931.13 RUS70887.1 - 0.0083 14.3 30.9 0.011 14.0 30.9 1.0 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RUS70887.1 - 0.032 12.5 20.3 0.039 12.2 20.3 1.0 1 0 0 1 1 1 0 Nop14-like family C2-set_2 PF08205.12 RUS70887.1 - 0.072 13.2 0.1 0.16 12.0 0.1 1.6 2 0 0 2 2 1 0 CD80-like C2-set immunoglobulin domain Mpp10 PF04006.12 RUS70887.1 - 0.18 10.2 14.0 0.24 9.8 14.0 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF3402 PF11882.8 RUS70887.1 - 0.22 10.6 0.7 0.3 10.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) SDA1 PF05285.12 RUS70887.1 - 0.24 10.8 21.1 0.3 10.5 21.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 RUS70887.1 - 0.85 7.8 19.2 1.1 7.4 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 RUS70887.1 - 0.94 8.3 12.9 1.3 7.9 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.9 RUS70887.1 - 1.7 7.7 40.5 2.8 7.0 40.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CNDH2_C PF16858.5 RUS70887.1 - 4.5 7.0 11.8 6.2 6.6 11.8 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CobT PF06213.12 RUS70887.1 - 7 6.0 19.0 10 5.4 19.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 RUS70887.1 - 8.7 6.1 11.4 15 5.3 11.4 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RRN3 PF05327.11 RUS70887.1 - 9.7 4.6 23.2 13 4.2 23.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VERL PF11386.8 RUS70889.1 - 0.066 13.4 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin WD40_like PF17005.5 RUS70890.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain DUF4959 PF16323.5 RUS70890.1 - 0.12 12.7 0.0 24 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) Na_Ca_ex PF01699.24 RUS70892.1 - 5.9e-32 110.7 16.6 7.3e-32 110.4 16.6 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein IncE PF17627.2 RUS70892.1 - 1.1 9.3 9.1 0.5 10.4 6.4 1.7 1 1 1 2 2 2 0 Inclusion membrane protein E HTH_48 PF17906.1 RUS70893.1 - 0.00022 21.3 0.3 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 RUS70893.1 - 0.00065 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain DUF4817 PF16087.5 RUS70893.1 - 0.023 14.5 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_24 PF13412.6 RUS70893.1 - 0.19 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MDM1 PF15501.6 RUS70894.1 - 2.9e-05 23.4 5.7 3.3e-05 23.3 5.7 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 RVT_1 PF00078.27 RUS70895.1 - 1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS70895.1 - 5.4e-09 36.5 0.0 1.4e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS70895.1 - 1.1e-07 32.3 0.0 3.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 RUS70895.1 - 0.00035 20.3 0.0 0.00099 18.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 RUS70895.1 - 0.00073 19.2 6.5 0.0019 17.9 6.5 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RVP PF00077.20 RUS70895.1 - 0.0041 17.4 0.1 0.015 15.6 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease HHH_9 PF17674.1 RUS70895.1 - 0.59 11.1 4.4 54 4.8 0.0 4.2 4 0 0 4 4 4 0 HHH domain DUF4196 PF13846.6 RUS70895.1 - 2.1 8.6 7.2 0.17 12.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Actin PF00022.19 RUS70896.1 - 3.3e-39 134.6 0.0 6.8e-35 120.5 0.0 3.7 1 1 1 2 2 2 2 Actin PH PF00169.29 RUS70896.1 - 7.5e-06 26.4 0.1 2.4e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 RUS70896.1 - 0.021 15.1 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain BcrAD_BadFG PF01869.20 RUS70896.1 - 0.041 13.4 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF2332 PF10094.9 RUS70896.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) PH_11 PF15413.6 RUS70896.1 - 1.2 9.6 8.2 0.73 10.3 2.7 2.9 3 1 0 4 4 4 0 Pleckstrin homology domain DUF550 PF04447.12 RUS70897.1 - 1.5e-10 41.1 41.6 14 5.8 0.0 15.5 2 1 14 16 16 16 16 Protein of unknown function (DUF550) DUF1402 PF07182.11 RUS70897.1 - 4e-08 32.7 40.1 17 4.3 0.0 14.8 1 1 15 16 16 16 15 Protein of unknown function (DUF1402) BHD_2 PF10404.9 RUS70898.1 - 1.9e-07 31.9 52.6 1.7e+02 3.3 0.8 22.2 1 1 25 26 26 26 0 Rad4 beta-hairpin domain 2 LRR_RI_capping PF18779.1 RUS70898.1 - 0.053 13.2 114.1 90 2.8 0.2 28.0 1 1 30 31 31 31 0 Capping Ribonuclease inhibitor Leucine Rich Repeat BILBO1_N PF18281.1 RUS70898.1 - 0.81 10.1 63.6 64 4.1 0.5 13.3 1 1 19 20 20 20 0 BILBO1 N-terminal domain Scramblase PF03803.15 RUS70901.1 - 4.5e-38 130.7 0.7 5.3e-38 130.5 0.7 1.0 1 0 0 1 1 1 1 Scramblase CiPC PF15800.5 RUS70901.1 - 0.024 14.4 1.0 0.031 14.0 1.0 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian PcfK PF14058.6 RUS70902.1 - 2.8e-06 27.7 8.4 4.4e-06 27.0 8.4 1.4 1 0 0 1 1 1 1 PcfK-like protein YL1 PF05764.13 RUS70902.1 - 1.6e-05 25.2 10.6 2.1e-05 24.8 10.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Eapp_C PF10238.9 RUS70902.1 - 0.00014 22.0 1.5 0.00018 21.6 1.5 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein Connexin PF00029.19 RUS70902.1 - 0.00058 19.7 3.4 0.00081 19.2 3.4 1.2 1 0 0 1 1 1 1 Connexin Gti1_Pac2 PF09729.9 RUS70902.1 - 0.00059 20.0 1.5 0.00072 19.7 1.5 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family CPSF100_C PF13299.6 RUS70902.1 - 0.00065 19.9 3.4 0.00092 19.4 3.4 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 RUS70902.1 - 0.0019 17.9 3.1 0.0027 17.5 3.1 1.2 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus Rtf2 PF04641.12 RUS70902.1 - 0.0021 17.5 13.3 0.0036 16.7 13.3 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger DUF4770 PF15994.5 RUS70902.1 - 0.0022 18.3 5.3 0.0032 17.7 5.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) SpoIIP PF07454.11 RUS70902.1 - 0.0024 17.4 4.2 0.0031 17.0 4.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 RUS70902.1 - 0.0034 17.6 0.1 0.0036 17.5 0.1 1.2 1 0 0 1 1 1 1 DDHD domain Rrn6 PF10214.9 RUS70902.1 - 0.0082 14.7 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor EOS1 PF12326.8 RUS70902.1 - 0.0083 16.1 0.2 0.011 15.7 0.2 1.2 1 0 0 1 1 1 1 N-glycosylation protein Afi1 PF07792.12 RUS70902.1 - 0.018 15.6 2.0 0.028 14.9 2.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SRP-alpha_N PF04086.13 RUS70902.1 - 0.018 15.0 14.3 0.025 14.5 14.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Tim54 PF11711.8 RUS70902.1 - 0.019 13.8 8.4 0.027 13.2 8.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Thg1C PF14413.6 RUS70902.1 - 0.022 14.9 7.2 0.043 14.0 7.2 1.6 1 0 0 1 1 1 0 Thg1 C terminal domain Presenilin PF01080.17 RUS70902.1 - 0.024 13.4 0.3 0.027 13.3 0.3 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 RUS70902.1 - 0.028 13.3 0.7 0.031 13.2 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Rxt3 PF08642.10 RUS70902.1 - 0.031 15.1 2.7 0.052 14.3 2.7 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF3405 PF11885.8 RUS70902.1 - 0.031 12.9 2.3 0.038 12.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) BSMAP PF12280.8 RUS70902.1 - 0.033 14.4 0.9 0.049 13.8 0.9 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein THOC2_N PF16134.5 RUS70902.1 - 0.033 12.8 3.5 0.044 12.4 3.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PPL5 PF18168.1 RUS70902.1 - 0.038 13.3 7.2 0.056 12.7 7.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SLD3 PF08639.10 RUS70902.1 - 0.051 12.3 14.7 0.069 11.9 14.7 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Jak1_Phl PF17887.1 RUS70902.1 - 0.052 13.5 10.9 0.093 12.7 10.9 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF2126 PF09899.9 RUS70902.1 - 0.052 11.6 1.2 0.069 11.2 1.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Membralin PF09746.9 RUS70902.1 - 0.066 12.2 5.4 0.093 11.8 5.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein SR-25 PF10500.9 RUS70902.1 - 0.074 12.7 37.4 0.13 11.8 37.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3807 PF12720.7 RUS70902.1 - 0.11 12.7 15.8 0.18 12.1 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peroxin-13_N PF04088.13 RUS70902.1 - 0.12 12.7 3.4 0.19 12.0 3.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MAS20 PF02064.15 RUS70902.1 - 0.12 12.4 9.2 0.21 11.7 9.2 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Zip PF02535.22 RUS70902.1 - 0.15 11.3 1.3 0.21 10.7 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.20 RUS70902.1 - 0.18 10.1 5.2 0.22 9.7 5.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RUS70902.1 - 0.18 10.6 1.9 0.27 10.0 1.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter RR_TM4-6 PF06459.12 RUS70902.1 - 0.23 11.2 14.2 0.35 10.6 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 RUS70902.1 - 0.25 10.2 20.6 0.34 9.8 20.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DcuA_DcuB PF03605.14 RUS70902.1 - 0.45 9.4 2.3 0.69 8.7 2.3 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter ORC5_C PF14630.6 RUS70902.1 - 0.76 9.2 7.7 1.3 8.4 7.7 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus RNA_pol_Rpc4 PF05132.14 RUS70902.1 - 0.85 10.0 14.4 1.5 9.2 14.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1764 PF08576.10 RUS70902.1 - 1.4 9.8 22.2 2.7 8.9 22.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) V_ATPase_I PF01496.19 RUS70902.1 - 1.6 6.5 6.8 2.2 6.1 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPN2_C PF18004.1 RUS70902.1 - 2.3 8.1 24.5 3.7 7.5 24.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Folate_carrier PF01770.18 RUS70902.1 - 2.3 6.8 5.6 3.2 6.4 5.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.14 RUS70902.1 - 2.5 6.3 11.6 3.4 5.8 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 RUS70902.1 - 2.6 7.0 3.5 3.6 6.5 3.5 1.1 1 0 0 1 1 1 0 CLN3 protein Peptidase_S49_N PF08496.10 RUS70902.1 - 2.7 8.1 23.5 6.3 6.9 23.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Orf78 PF06024.12 RUS70902.1 - 2.7 8.3 6.7 4.8 7.5 6.3 1.5 2 0 0 2 2 1 0 Orf78 (ac78) ORC_WH_C PF18137.1 RUS70902.1 - 2.7 8.0 12.8 5 7.2 12.8 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Vfa1 PF08432.10 RUS70902.1 - 2.7 8.3 26.2 4.3 7.6 26.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3464 PF11947.8 RUS70902.1 - 3.3 7.5 19.3 5.3 6.8 19.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CENP-N PF05238.13 RUS70902.1 - 3.3 6.9 11.3 4.8 6.4 11.3 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2828 PF11443.8 RUS70902.1 - 3.5 5.6 14.9 4.8 5.1 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Paramyxo_ncap PF00973.19 RUS70902.1 - 5.4 5.8 7.4 7.6 5.3 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein IHABP4_N PF16174.5 RUS70902.1 - 6.8 7.3 22.7 16 6.0 22.7 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ureide_permease PF07168.11 RUS70902.1 - 7 5.3 7.1 4.8 5.8 5.6 1.5 2 0 0 2 2 1 0 Ureide permease Lipoprotein_15 PF03640.15 RUS70903.1 - 2.2e-22 78.3 10.3 51 3.5 0.0 17.4 18 0 0 18 18 18 17 Secreted repeat of unknown function VbhA PF18495.1 RUS70903.1 - 0.25 11.3 54.9 2e+02 1.9 0.1 16.7 18 0 0 18 18 18 0 Antitoxin VbhA cEGF PF12662.7 RUS70904.1 - 1.1e-25 89.2 55.7 4.6e-06 26.5 0.6 12.6 13 0 0 13 13 13 7 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS70904.1 - 4.9e-22 77.9 52.8 8.5e-09 35.5 4.9 12.2 12 2 1 13 13 13 5 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS70904.1 - 3.7e-16 59.1 59.6 3.4e-08 33.6 5.7 10.5 10 0 0 10 10 10 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS70904.1 - 1.6e-10 41.1 111.3 0.0016 18.7 6.0 10.1 11 0 0 11 11 11 7 EGF-like domain hEGF PF12661.7 RUS70904.1 - 1.3e-05 25.6 116.2 0.013 16.1 5.4 11.4 11 0 0 11 11 11 4 Human growth factor-like EGF EGF_2 PF07974.13 RUS70904.1 - 0.0058 17.0 12.6 0.0058 17.0 12.6 9.0 8 0 0 8 8 8 3 EGF-like domain YoeB_toxin PF06769.14 RUS70904.1 - 0.018 15.0 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Somatomedin_B PF01033.17 RUS70905.1 - 1.2e-06 28.8 16.7 1.2e-06 28.8 16.7 2.4 2 0 0 2 2 2 1 Somatomedin B domain Tropomyosin_1 PF12718.7 RUS70906.1 - 0.0058 16.8 0.6 0.0075 16.4 0.6 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 RUS70906.1 - 0.067 12.5 9.3 0.61 9.4 0.6 1.9 1 1 1 2 2 2 0 Tropomyosin Lipocalin_2 PF08212.12 RUS70906.1 - 0.15 12.0 13.4 0.61 10.0 0.4 3.4 1 1 2 3 3 3 0 Lipocalin-like domain CsbD PF05532.12 RUS70906.1 - 0.34 10.8 28.5 3.8 7.5 2.3 3.8 1 1 2 3 3 3 0 CsbD-like HrpB7 PF09486.10 RUS70906.1 - 1 9.8 4.8 5.7 7.3 0.2 2.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF3297 PF11730.8 RUS70906.1 - 1.5 8.8 12.4 19 5.2 0.1 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3297) Rhamnogal_lyase PF06045.11 RUS70906.1 - 5.4 6.4 11.6 2.5 7.5 2.0 2.5 1 1 1 2 2 2 0 Rhamnogalacturonate lyase family DUF5325 PF17259.2 RUS70908.1 - 0.0073 16.2 0.7 0.012 15.5 0.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5325) SID-1_RNA_chan PF13965.6 RUS70908.1 - 0.0074 14.8 0.0 0.0084 14.6 0.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 TMEM154 PF15102.6 RUS70908.1 - 0.021 14.7 0.7 0.039 13.9 0.4 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF4834 PF16118.5 RUS70908.1 - 0.029 15.3 0.0 0.055 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 RUS70908.1 - 0.065 14.1 0.0 0.1 13.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 RUS70908.1 - 0.084 13.6 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Spt20 PF12090.8 RUS70909.1 - 0.0027 17.4 12.9 0.0027 17.4 12.9 4.3 4 0 0 4 4 4 1 Spt20 family DUF1856 PF08983.10 RUS70910.1 - 0.015 15.5 4.9 7.8 6.8 0.1 4.8 1 1 5 6 6 6 0 Domain of unknown function (DUF1856) T2SSN PF01203.19 RUS70910.1 - 0.02 15.1 9.3 0.11 12.7 9.3 2.1 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein N Colipase-like PF15083.6 RUS70910.1 - 0.027 14.6 7.3 0.48 10.6 2.3 2.4 1 1 1 2 2 2 0 Colipase-like DUF4334 PF14232.6 RUS70910.1 - 0.043 13.8 2.4 1.7e+02 2.3 0.0 4.7 4 1 0 5 5 5 0 Domain of unknown function (DUF4334) Peptidase_C33 PF05412.12 RUS70910.1 - 0.11 12.5 10.5 2.2 8.4 1.2 3.2 1 1 2 3 3 3 0 Equine arterivirus Nsp2-type cysteine proteinase WBP-1 PF11669.8 RUS70912.1 - 0.31 11.7 0.1 0.31 11.7 0.1 2.6 4 0 0 4 4 4 0 WW domain-binding protein 1 Nup192 PF11894.8 RUS70914.1 - 0 1101.2 0.1 0 1100.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 zf-BED PF02892.15 RUS70914.1 - 0.1 12.6 0.2 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 BED zinc finger Filo_VP35 PF02097.15 RUS70915.1 - 0.38 9.8 8.3 74 2.2 0.0 5.7 2 1 5 7 7 7 0 Filoviridae VP35 RVT_1 PF00078.27 RUS70916.1 - 1e-54 185.4 0.8 1.7e-54 184.7 0.8 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS70916.1 - 2e-13 50.7 0.0 8.3e-13 48.7 0.0 2.2 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS70916.1 - 0.063 14.0 0.3 0.063 14.0 0.3 2.4 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DAG1 PF05454.11 RUS70917.1 - 0.00034 20.1 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Pox_A14 PF05767.12 RUS70917.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 EphA2_TM PF14575.6 RUS70917.1 - 0.041 14.8 0.1 0.071 14.0 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.10 RUS70917.1 - 0.064 13.0 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide BCLP PF12304.8 RUS70917.1 - 0.076 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Beta-casein like protein Syntaxin-6_N PF09177.11 RUS70917.1 - 0.12 13.0 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal V-set PF07686.17 RUS70919.1 - 0.079 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF1372 PF07116.11 RUS70920.1 - 0.13 12.5 0.3 8 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) FeoB_associated PF12669.7 RUS70920.1 - 0.35 11.3 3.7 0.63 10.5 0.1 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein 7TM_GPCR_Srw PF10324.9 RUS70921.1 - 0.00049 19.5 0.7 0.00062 19.2 0.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Ras PF00071.22 RUS70922.1 - 6.9e-30 103.8 0.0 7.9e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS70922.1 - 7.9e-11 42.2 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS70922.1 - 0.14 12.6 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 RUS70922.1 - 0.21 11.0 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family FPP PF05911.11 RUS70923.1 - 0.13 10.5 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil MFS_1 PF07690.16 RUS70924.1 - 3.6e-26 91.9 46.4 2.3e-17 63.0 10.0 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 RUS70924.1 - 1e-08 34.9 25.0 2e-06 27.4 5.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 RUS70924.1 - 0.00032 19.5 9.4 0.00055 18.7 9.4 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SpoVAB PF13782.6 RUS70924.1 - 0.26 11.6 6.5 0.056 13.7 0.8 2.5 2 0 0 2 2 2 0 Stage V sporulation protein AB Mito_carr PF00153.27 RUS70926.1 - 1.5e-53 178.6 2.9 1.2e-18 66.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MurJ PF03023.14 RUS70926.1 - 0.004 15.8 0.1 0.0058 15.3 0.1 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ DUF4257 PF14074.6 RUS70926.1 - 0.21 11.8 4.8 0.5 10.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) SDA1 PF05285.12 RUS70927.1 - 4.5e-07 29.6 47.7 4.7e-07 29.6 47.7 1.1 1 0 0 1 1 1 1 SDA1 RNA_pol_Rpc4 PF05132.14 RUS70927.1 - 0.0067 16.9 16.7 0.033 14.6 16.3 1.9 1 1 0 1 1 1 1 RNA polymerase III RPC4 Presenilin PF01080.17 RUS70927.1 - 0.0081 15.0 11.1 0.0092 14.8 11.1 1.1 1 0 0 1 1 1 1 Presenilin MDM1 PF15501.6 RUS70927.1 - 0.12 11.5 10.4 0.12 11.5 10.4 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF2151 PF10221.9 RUS70927.1 - 0.17 10.4 7.6 0.17 10.4 7.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Apt1 PF10351.9 RUS70927.1 - 0.33 9.8 10.9 0.36 9.6 10.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 RUS70927.1 - 0.82 8.8 11.4 1.4 8.0 11.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 RUS70927.1 - 1.4 7.7 21.7 2 7.1 21.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 RUS70927.1 - 4.3 6.9 10.3 5.4 6.5 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA_11 PF13086.6 RUS70927.1 - 4.8 6.9 7.0 5.9 6.6 7.0 1.1 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.16 RUS70927.1 - 9 5.7 7.6 12 5.3 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 WW PF00397.26 RUS70928.1 - 2.3e-09 37.2 1.9 2.3e-09 37.2 1.9 2.8 3 0 0 3 3 3 1 WW domain Radial_spoke PF04712.12 RUS70929.1 - 4e-194 646.1 4.5 4e-194 646.1 4.5 1.6 1 1 1 2 2 2 1 Radial spokehead-like protein SDA1 PF05285.12 RUS70929.1 - 0.00029 20.4 2.5 0.00029 20.4 2.5 3.0 3 0 0 3 3 3 2 SDA1 Pkinase_Tyr PF07714.17 RUS70930.1 - 6.2e-31 107.6 0.0 2.3e-20 73.0 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS70930.1 - 1.8e-21 76.7 0.0 9.4e-16 58.0 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Guanylate_cyc PF00211.20 RUS70930.1 - 2e-18 66.7 0.2 4.3e-10 39.5 0.0 2.8 2 1 1 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS70930.1 - 8.5e-06 25.4 6.3 0.00018 21.0 2.6 2.3 2 0 0 2 2 2 2 Heme NO binding associated Macoilin PF09726.9 RUS70930.1 - 0.0012 17.5 0.1 0.0016 17.1 0.1 1.1 1 0 0 1 1 1 1 Macoilin family DUF4834 PF16118.5 RUS70930.1 - 0.0072 17.3 1.0 0.049 14.6 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) dsDNA_bind PF01984.20 RUS70930.1 - 0.028 14.7 8.7 0.95 9.8 6.2 2.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF4598 PF15370.6 RUS70930.1 - 0.068 13.6 2.6 0.072 13.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) DUF3087 PF11286.8 RUS70930.1 - 0.087 12.3 0.1 0.087 12.3 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3087) Suf PF05843.14 RUS70930.1 - 0.098 12.6 1.6 0.67 9.9 0.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MTABC_N PF16185.5 RUS70930.1 - 0.13 11.8 0.6 0.79 9.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Spt20 PF12090.8 RUS70930.1 - 0.42 10.2 11.5 1.3 8.6 11.5 1.7 1 0 0 1 1 1 0 Spt20 family EphA2_TM PF14575.6 RUS70930.1 - 0.63 11.0 3.2 13 6.7 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Presenilin PF01080.17 RUS70930.1 - 4.4 6.0 4.5 3.7 6.2 3.0 1.6 2 0 0 2 2 2 0 Presenilin Glyco_hydro_38N PF01074.22 RUS70932.1 - 2.9e-90 302.6 3.4 4.8e-90 301.8 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS70932.1 - 6.9e-38 130.9 0.0 1.3e-37 129.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RUS70932.1 - 3.6e-19 68.7 0.1 7.4e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 RUS70932.1 - 8.8e-07 28.9 0.0 3.1e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain RRM_1 PF00076.22 RUS70933.1 - 1.2e-07 31.4 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS70933.1 - 0.00029 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_3 PF15663.5 RUS70933.1 - 0.011 15.9 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family UBA PF00627.31 RUS70933.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Limkain-b1 PF11608.8 RUS70933.1 - 0.024 14.7 0.0 0.063 13.4 0.0 1.6 2 0 0 2 2 2 0 Limkain b1 zf-CCCH PF00642.24 RUS70933.1 - 0.15 12.0 1.8 0.33 10.9 1.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS70933.1 - 0.24 11.5 5.5 0.52 10.4 5.5 1.6 1 0 0 1 1 1 0 Zinc finger domain FYVE PF01363.21 RUS70934.1 - 2e-20 72.7 14.0 2e-20 72.7 14.0 3.1 2 0 0 2 2 2 1 FYVE zinc finger PGBA_C PF15437.6 RUS70934.1 - 0.97 9.8 12.9 0.085 13.2 6.6 2.4 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal FBPase PF00316.20 RUS70935.1 - 7e-75 250.6 0.1 9.5e-75 250.2 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 RUS70935.1 - 0.0028 17.2 0.0 0.0068 15.9 0.0 1.6 2 0 0 2 2 2 1 Inositol monophosphatase family SHR-BD PF06650.12 RUS70936.1 - 1.1e-14 54.5 0.0 1.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF1203 PF06718.11 RUS70936.1 - 0.077 13.3 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Glycophorin_A PF01102.18 RUS70937.1 - 0.039 14.2 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A DUF4514 PF14986.6 RUS70937.1 - 0.043 13.8 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Cadherin_C_2 PF16492.5 RUS70937.1 - 0.98 10.2 4.9 3.5 8.5 4.9 2.1 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Methyltransf_11 PF08241.12 RUS70938.1 - 1.6e-20 73.5 0.0 2.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS70938.1 - 1.3e-17 64.3 0.0 2.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS70938.1 - 1.6e-11 44.8 0.1 3.9e-11 43.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS70938.1 - 1.3e-09 38.0 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS70938.1 - 8.9e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS70938.1 - 4.1e-07 29.6 0.0 8.6e-07 28.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 RUS70938.1 - 2.5e-05 23.9 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 RUS70938.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 RUS70938.1 - 0.0028 17.0 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 RUS70938.1 - 0.0038 16.3 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_2 PF00891.18 RUS70938.1 - 0.0062 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 RUS70938.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.11 RUS70938.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) REC1 PF18501.1 RUS70938.1 - 0.056 13.3 0.3 0.15 12.0 0.3 1.7 1 1 0 1 1 1 0 Alpha helical recognition lobe domain Methyltransf_4 PF02390.17 RUS70938.1 - 0.088 12.3 0.1 0.48 9.9 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase CEP44 PF15007.6 RUS70938.1 - 0.12 12.6 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Methyltransf_33 PF10017.9 RUS70938.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Arm PF00514.23 RUS70940.1 - 1e-29 101.6 10.5 2.4e-08 33.7 0.1 7.9 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS70940.1 - 4.9e-08 33.2 0.9 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 RUS70940.1 - 7e-07 29.6 2.4 0.6 10.7 0.2 5.4 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 RUS70940.1 - 0.00025 21.1 1.4 0.25 11.7 0.4 3.8 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 RUS70940.1 - 0.0011 19.1 0.7 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 RUS70940.1 - 0.012 13.8 2.8 0.32 9.1 0.5 2.1 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 RUS70940.1 - 0.041 12.4 1.6 0.56 8.7 0.2 2.1 2 0 0 2 2 2 0 Adaptin N terminal region Arm_2 PF04826.13 RUS70940.1 - 0.066 12.7 0.7 8.6 5.7 0.1 3.0 2 1 1 3 3 3 0 Armadillo-like DIM1 PF02966.16 RUS70941.1 - 9.2e-67 222.9 0.5 1e-66 222.7 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 RUS70941.1 - 2e-05 24.5 0.1 2.6e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 RUS70941.1 - 0.0076 16.2 1.5 0.012 15.6 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 RUS70941.1 - 0.045 13.9 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 RUS70941.1 - 0.086 13.2 0.5 0.13 12.6 0.5 1.4 1 1 0 1 1 1 0 Thioredoxin-like Peptidase_M54 PF07998.11 RUS70942.1 - 2.5e-09 37.4 0.1 4.3e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 RUS70942.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Matrixin SDA1 PF05285.12 RUS70943.1 - 0.00053 19.5 22.0 0.00053 19.5 22.0 1.1 1 0 0 1 1 1 1 SDA1 BASP1 PF05466.12 RUS70943.1 - 3.2 7.7 27.7 4.5 7.2 27.7 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) SOBP PF15279.6 RUS70943.1 - 3.9 8.0 5.3 4.8 7.7 5.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Integrase_H2C2 PF17921.1 RUS70944.1 - 2.3e-22 78.8 0.1 3.7e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS70944.1 - 5.8e-07 29.7 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS70944.1 - 1.2e-06 28.6 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 RUS70945.1 - 9.7e-34 115.4 0.0 2.9e-33 113.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS70945.1 - 3.3e-33 114.1 0.0 9e-33 112.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS70945.1 - 5.5e-22 78.4 0.0 9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) POTRA_TamA_1 PF17243.2 RUS70945.1 - 0.16 12.1 0.0 32 4.7 0.0 2.5 2 0 0 2 2 2 0 POTRA domain TamA domain 1 REJ PF02010.15 RUS70946.1 - 0.096 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 REJ domain Lectin_C PF00059.21 RUS70948.1 - 1.3e-14 54.9 3.1 4.9e-07 30.4 0.4 2.3 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 RUS70948.1 - 4.4e-06 26.5 0.1 0.0057 16.3 0.0 2.3 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like CPW_WPC PF09717.10 RUS70948.1 - 0.004 18.1 0.6 1.7 9.7 0.1 3.0 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Dynein_IC2 PF11540.8 RUS70949.1 - 0.79 9.7 4.3 1.3e+02 2.6 0.0 4.5 6 0 0 6 6 6 0 Cytoplasmic dynein 1 intermediate chain 2 3-HAO PF06052.12 RUS70949.1 - 1.3 8.7 13.1 3 7.5 1.6 4.3 1 1 5 6 6 6 0 3-hydroxyanthranilic acid dioxygenase EF_TS PF00889.19 RUS70950.1 - 1.9e-27 96.3 0.0 9.7e-27 93.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS Sulfatase PF00884.23 RUS70951.1 - 1.9e-49 168.7 0.0 5.8e-49 167.1 0.0 1.7 1 1 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 RUS70951.1 - 0.00036 19.7 0.0 0.015 14.4 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 RUS70951.1 - 0.0043 16.7 0.0 0.73 9.4 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3645 PF12359.8 RUS70951.1 - 0.036 13.4 0.5 0.09 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) DUF229 PF02995.17 RUS70951.1 - 0.038 12.6 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_C1 PF00112.23 RUS70952.1 - 1.5e-50 172.3 11.0 2e-50 171.9 11.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ig_2 PF13895.6 RUS70953.1 - 4.4e-32 110.3 1.1 5.3e-09 36.3 0.1 5.3 4 1 1 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.6 RUS70953.1 - 3.2e-24 85.3 0.5 5.7e-06 26.8 0.1 5.1 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 RUS70953.1 - 3.9e-14 52.6 4.5 0.0013 18.9 0.1 4.6 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 RUS70953.1 - 4.1e-09 36.4 0.0 0.13 12.4 0.0 5.1 4 2 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 RUS70953.1 - 5.8e-09 36.1 3.0 1 9.6 0.1 6.6 4 3 3 7 7 7 3 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS70953.1 - 4.7e-07 30.0 0.0 0.1 12.9 0.0 4.4 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS70953.1 - 6.8e-06 26.1 0.0 0.29 11.2 0.0 3.5 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 RUS70953.1 - 2.2e-05 24.8 0.0 0.27 11.7 0.0 4.3 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pentapeptide_4 PF13599.6 RUS70954.1 - 3e-07 30.5 6.8 0.0036 17.4 0.2 2.6 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) DNA_gyraseB_C PF00986.21 RUS70954.1 - 0.04 14.1 4.6 2.9 8.1 0.3 2.9 1 1 1 2 2 2 0 DNA gyrase B subunit, carboxyl terminus 7tm_1 PF00001.21 RUS70955.1 - 5.9e-13 48.7 4.7 7.8e-13 48.4 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS70955.1 - 1.1e-05 25.3 3.8 1.3e-05 25.1 3.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 RUS70957.1 - 6.8e-08 32.2 0.0 1.4e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cementoin PF10511.9 RUS70957.1 - 3.3 8.1 4.8 1.8 9.0 1.4 2.3 2 0 0 2 2 2 0 Trappin protein transglutaminase binding domain Zip PF02535.22 RUS70959.1 - 1.1e-48 166.1 0.9 1.2e-46 159.4 0.9 2.6 1 1 0 1 1 1 1 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 RUS70959.1 - 0.042 12.3 0.9 0.41 9.0 0.0 2.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 BUD22 PF09073.10 RUS70959.1 - 0.1 11.9 5.3 0.23 10.7 5.3 1.5 1 0 0 1 1 1 0 BUD22 PCI PF01399.27 RUS70960.1 - 1.9e-25 89.4 4.5 5.9e-25 87.8 1.7 2.6 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 RUS70960.1 - 2.4e-05 24.0 3.8 4.5 7.5 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF4704 PF15787.5 RUS70960.1 - 0.0066 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) TPR_1 PF00515.28 RUS70960.1 - 0.025 14.4 6.6 23 5.0 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS70960.1 - 0.03 14.4 4.3 21 5.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS70960.1 - 0.37 11.1 3.5 20 5.5 0.0 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat YL1_C PF08265.11 RUS70961.1 - 1.3e-13 50.4 0.1 1.8e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ank_2 PF12796.7 RUS70965.1 - 2.8e-35 120.7 5.9 3.4e-11 43.6 0.0 5.3 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS70965.1 - 2.1e-30 104.7 8.5 8.4e-08 32.6 0.1 8.1 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS70965.1 - 8.7e-26 87.2 11.2 5.4e-05 23.3 0.1 10.0 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 RUS70965.1 - 2.5e-25 87.8 21.2 1.6e-05 25.1 0.8 9.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS70965.1 - 3.3e-22 78.3 8.5 1.6e-06 28.3 0.2 6.1 7 1 1 8 8 8 5 Ankyrin repeats (many copies) FeoA PF04023.14 RUS70965.1 - 0.017 15.3 0.0 11 6.4 0.0 3.4 3 0 0 3 3 3 0 FeoA domain LRR_8 PF13855.6 RUS70966.1 - 3.6e-54 180.4 92.9 4.3e-13 48.8 11.2 10.3 5 2 7 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 RUS70966.1 - 1.9e-26 91.7 74.0 0.00012 22.4 5.7 13.0 8 3 4 13 13 13 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS70966.1 - 8.4e-16 58.1 26.6 4.5e-09 36.4 4.3 5.0 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 RUS70966.1 - 6.5e-06 25.7 3.1 2.1e-05 24.0 3.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 RUS70966.1 - 2.1e-05 24.1 21.9 0.15 11.6 0.3 5.4 3 3 1 6 6 6 3 Leucine-rich repeat TIR_2 PF13676.6 RUS70966.1 - 0.00013 22.6 0.0 0.00043 20.9 0.0 1.9 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 RUS70966.1 - 0.023 15.2 62.6 0.97 10.2 0.2 14.3 14 2 1 15 15 15 0 Leucine Rich Repeat TIR PF01582.20 RUS70966.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 TIR domain PUNUT PF16913.5 RUS70967.1 - 7.3e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 RUS70967.1 - 0.00022 21.4 15.6 0.00069 19.8 2.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 RUS70967.1 - 0.027 13.4 9.8 0.24 10.3 9.8 2.0 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like DUF2207 PF09972.9 RUS70967.1 - 1.2 7.9 3.7 5 5.8 3.7 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-H2C2_2 PF13465.6 RUS70968.1 - 1.3e-08 34.8 17.5 3e-06 27.4 2.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS70968.1 - 0.0022 17.9 2.4 0.0022 17.9 2.4 4.0 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS70968.1 - 0.011 16.5 1.8 0.011 16.5 1.8 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS70968.1 - 0.44 11.1 27.2 0.052 14.0 1.9 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS70969.1 - 0.0014 19.0 7.4 0.14 12.7 1.4 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS70969.1 - 0.0014 19.0 7.3 0.048 14.1 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS70969.1 - 0.0031 18.2 4.9 2.2 9.4 0.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3739 PF12545.8 RUS70969.1 - 0.05 14.1 1.1 0.26 11.8 1.1 2.3 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein Elf1 PF05129.13 RUS70969.1 - 0.1 12.7 1.0 0.34 11.0 1.0 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-met PF12874.7 RUS70969.1 - 7.1 7.2 13.8 0.057 13.8 0.4 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ribosomal_L22e PF01776.17 RUS70970.1 - 3.5e-50 168.9 2.4 4.7e-50 168.5 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Ints3 PF10189.9 RUS70970.1 - 0.052 12.8 0.2 0.077 12.3 0.2 1.3 1 1 0 1 1 1 0 Integrator complex subunit 3 Homeodomain PF00046.29 RUS70972.1 - 2.4e-22 78.5 4.1 4.8e-22 77.6 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 RUS70972.1 - 0.094 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 RUS70972.1 - 0.13 12.2 1.4 0.33 10.9 1.4 1.8 1 1 0 1 1 1 0 Homeobox KN domain Ribosomal_S7e PF01251.18 RUS70974.1 - 3.3e-38 131.3 0.3 3.6e-38 131.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Methyltransf_22 PF13383.6 RUS70975.1 - 2.4e-19 69.9 0.1 3e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS70975.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain PITH PF06201.13 RUS70976.1 - 3.7e-41 140.9 0.0 4.7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain RTC PF01137.21 RUS70977.1 - 1.8e-80 269.3 0.2 2.1e-80 269.1 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RUS70977.1 - 6.5e-16 58.7 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Nbas_N PF15492.6 RUS70978.1 - 0.049 13.0 0.0 0.057 12.7 0.0 1.0 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Epimerase PF01370.21 RUS70979.1 - 1.8e-23 83.3 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS70979.1 - 1.3e-15 57.7 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS70979.1 - 1.4e-08 34.2 0.0 1.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 RUS70979.1 - 5.5e-06 25.6 0.0 8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RUS70979.1 - 0.00036 19.7 0.0 0.0036 16.5 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS70979.1 - 0.00042 19.6 0.0 0.0021 17.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Adeno_52K PF03052.15 RUS70979.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa LURAP PF14854.6 RUS70981.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 1.6 2 0 0 2 2 2 1 Leucine rich adaptor protein Nuc_sug_transp PF04142.15 RUS70982.1 - 3.3e-60 203.9 25.1 1.2e-45 156.1 10.1 2.1 1 1 1 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 RUS70982.1 - 0.00023 21.3 6.3 0.00023 21.3 6.3 2.6 1 1 1 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 RUS70982.1 - 0.027 13.7 12.6 0.064 12.5 11.2 2.0 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport SPC25 PF06703.11 RUS70982.1 - 2.6 7.8 6.6 0.82 9.4 1.5 2.2 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MFS_1 PF07690.16 RUS70983.1 - 7.8e-14 51.4 29.5 7.2e-10 38.3 7.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 RUS70983.1 - 0.00022 20.0 19.3 0.00038 19.1 9.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein DUF682 PF05081.12 RUS70983.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) MFS_1 PF07690.16 RUS70984.1 - 9.1e-23 80.7 23.1 5.1e-19 68.4 1.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS70984.1 - 5.9e-05 21.8 2.2 5.9e-05 21.8 2.2 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 RUS70984.1 - 0.00049 19.1 0.3 0.00049 19.1 0.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter HupE_UreJ PF04955.12 RUS70984.1 - 0.061 12.8 4.6 0.14 11.7 0.4 2.4 2 0 0 2 2 2 0 HupE / UreJ protein MFS_1 PF07690.16 RUS70986.1 - 1.1e-18 67.3 22.6 2.7e-17 62.7 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS70986.1 - 1.9e-07 30.0 14.9 0.00066 18.3 3.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 RUS70986.1 - 0.00023 20.2 11.2 0.0085 15.0 0.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Cohesin_HEAT PF12765.7 RUS70987.1 - 0.00094 19.4 0.3 1.5e+02 2.8 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Chromadorea_ALT PF05535.12 RUS70987.1 - 0.0093 16.1 18.1 1.4 9.1 0.7 6.2 1 1 6 7 7 7 1 Chromadorea ALT protein SLATT_6 PF18169.1 RUS70987.1 - 0.4 10.3 13.9 4.5 6.8 0.4 3.4 1 1 3 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 6 Endotoxin_M PF00555.19 RUS70987.1 - 0.43 10.6 14.8 1.6 8.8 3.3 3.3 1 1 4 5 5 5 0 delta endotoxin Macscav_rec PF03523.13 RUS70987.1 - 0.62 10.0 27.1 35 4.4 0.1 7.7 4 1 4 8 8 8 0 Macrophage scavenger receptor TIMELESS_C PF05029.13 RUS70988.1 - 2.6e-55 188.6 46.5 9.9e-41 140.5 1.4 4.7 3 2 1 4 4 4 2 Timeless protein C terminal region LRR_8 PF13855.6 RUS70989.1 - 3e-57 190.2 25.6 7.6e-18 64.0 0.1 8.4 5 2 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 RUS70989.1 - 1.3e-24 85.8 33.4 2.1e-06 28.0 3.2 8.7 5 3 2 9 9 9 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS70989.1 - 6.9e-12 45.4 0.2 1.4e-08 34.8 0.2 4.3 4 1 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS70989.1 - 2.2e-08 33.8 7.0 6e-06 25.9 0.1 4.0 2 2 1 3 3 3 2 Leucine-rich repeat LRRNT PF01462.18 RUS70989.1 - 0.0033 17.0 9.7 0.39 10.4 2.8 3.5 3 0 0 3 3 3 2 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 RUS70989.1 - 0.0068 16.4 18.8 16 5.8 0.0 9.0 9 0 0 9 9 9 2 Leucine Rich repeat LRRCT PF01463.24 RUS70989.1 - 0.035 14.7 0.0 0.091 13.3 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 RUS70989.1 - 3.9 8.4 29.7 7.4 7.6 0.0 10.2 10 3 1 11 11 11 0 Leucine Rich Repeat Lipase_chap PF03280.14 RUS70991.1 - 0.049 13.6 4.7 0.061 13.3 4.7 1.0 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein TMF_TATA_bd PF12325.8 RUS70991.1 - 0.4 10.9 9.5 1.8 8.8 9.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding efThoc1 PF11957.8 RUS70992.1 - 0.015 14.0 0.1 0.081 11.6 0.0 1.8 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor adh_short_C2 PF13561.6 RUS70993.1 - 1.8e-53 181.5 1.5 7.2e-53 179.5 1.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS70993.1 - 6.9e-47 159.4 3.3 7.9e-46 156.0 3.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS70993.1 - 8.2e-12 45.4 1.3 1.3e-11 44.7 1.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RUS70993.1 - 0.0072 16.2 0.6 0.013 15.4 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 RUS70993.1 - 0.033 14.0 0.2 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox_3 PF13738.6 RUS70993.1 - 0.077 12.2 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rad21_Rec8_N PF04825.13 RUS70994.1 - 2.1e-40 137.3 0.0 5.3e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RUS70994.1 - 1.4e-16 59.5 0.1 9.3e-16 56.9 0.0 2.3 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 RUS70994.1 - 0.0071 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Lipase_GDSL PF00657.22 RUS70995.1 - 3.5e-14 53.2 0.0 4.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RUS70995.1 - 1.2e-08 35.6 0.0 2.7e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_11 PF08241.12 RUS70996.1 - 2e-10 41.1 0.0 4.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS70996.1 - 9e-10 39.1 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS70996.1 - 0.00036 19.9 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RUS70996.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS70996.1 - 0.0019 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 RUS70996.1 - 0.14 10.7 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NAR2 PF16974.5 RUS70996.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory MTS PF05175.14 RUS70996.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain OTU PF02338.19 RUS70997.1 - 1.1e-05 25.9 0.2 2.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease PHD PF00628.29 RUS70997.1 - 3.5e-05 23.6 8.6 3.5e-05 23.6 8.6 2.3 2 0 0 2 2 2 1 PHD-finger Peptidase_C65 PF10275.9 RUS70997.1 - 0.00034 20.1 2.2 0.00092 18.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase C65 Otubain PHD_2 PF13831.6 RUS70997.1 - 0.0027 17.2 2.9 0.0027 17.2 2.9 3.1 4 0 0 4 4 4 1 PHD-finger C1_1 PF00130.22 RUS70997.1 - 0.0074 16.1 2.9 0.0074 16.1 2.9 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MDM31_MDM32 PF08118.11 RUS70997.1 - 0.13 11.0 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins C1_2 PF03107.16 RUS70997.1 - 0.24 11.7 6.1 0.085 13.2 1.3 2.5 2 0 0 2 2 2 0 C1 domain Trypsin PF00089.26 RUS70999.1 - 1.1e-22 80.9 0.0 4.8e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 Trypsin Somatomedin_B PF01033.17 RUS71000.1 - 0.00019 21.8 14.0 0.00019 21.8 14.0 2.0 2 0 0 2 2 2 1 Somatomedin B domain Metallophos PF00149.28 RUS71001.1 - 2.7e-08 34.5 0.0 4.7e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Lyase_1 PF00206.20 RUS71002.1 - 8.6e-102 340.7 0.0 1.7e-101 339.7 0.0 1.5 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 RUS71002.1 - 2.8e-20 72.8 0.0 7e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Perilipin PF03036.16 RUS71002.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Perilipin family MLANA PF14991.6 RUS71003.1 - 0.036 14.3 0.6 0.086 13.1 0.1 1.7 1 1 1 2 2 2 0 Protein melan-A Prion PF00377.18 RUS71003.1 - 0.075 12.9 3.6 6.2 6.7 0.0 2.7 2 1 0 2 2 2 0 Prion/Doppel alpha-helical domain Aph-1 PF06105.12 RUS71003.1 - 0.094 12.1 0.2 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Aph-1 protein RRM_3 PF08777.11 RUS71003.1 - 0.22 11.6 1.9 0.37 10.8 1.9 1.3 1 0 0 1 1 1 0 RNA binding motif Thioredoxin PF00085.20 RUS71004.1 - 3.8e-11 42.9 0.0 6.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Acyl-CoA_dh_1 PF00441.24 RUS71005.1 - 3.6e-46 157.1 3.1 5.9e-46 156.4 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS71005.1 - 2.5e-33 115.1 0.1 1.6e-32 112.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS71005.1 - 3.2e-24 85.7 2.0 4.5e-24 85.2 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS71005.1 - 2.3e-11 43.7 0.0 5.5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyclin_N PF00134.23 RUS71006.1 - 0.00073 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RUS71006.1 - 0.024 15.0 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin Sulfotransfer_2 PF03567.14 RUS71007.1 - 3.4e-08 33.7 1.6 0.00084 19.3 0.4 2.4 2 0 0 2 2 2 2 Sulfotransferase family DUF4688 PF15752.5 RUS71007.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) FapA PF03961.13 RUS71007.1 - 0.39 9.3 5.0 0.56 8.7 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sulfotransfer_2 PF03567.14 RUS71008.1 - 2.3e-10 40.8 0.4 2.1e-07 31.1 0.0 2.6 3 0 0 3 3 3 2 Sulfotransferase family Band_7 PF01145.25 RUS71009.1 - 1.6e-19 70.6 5.4 2e-19 70.3 0.0 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family bZIP_1 PF00170.21 RUS71009.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.0 3 0 0 3 3 3 0 bZIP transcription factor DivIVA PF05103.13 RUS71009.1 - 0.014 15.5 7.9 0.024 14.7 7.9 1.4 1 0 0 1 1 1 0 DivIVA protein Band_7_1 PF13421.6 RUS71009.1 - 0.021 14.5 0.1 0.067 12.9 0.0 1.7 1 1 1 2 2 2 0 SPFH domain-Band 7 family V-ATPase_G_2 PF16999.5 RUS71009.1 - 0.025 15.0 8.9 0.025 15.0 8.9 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4201 PF13870.6 RUS71009.1 - 0.039 13.7 2.5 0.073 12.8 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 RUS71009.1 - 0.11 11.5 4.0 0.16 11.0 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_B PF00430.18 RUS71009.1 - 0.15 12.1 16.6 0.53 10.4 15.4 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF2959 PF11172.8 RUS71009.1 - 0.37 10.9 6.4 0.32 11.1 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) GBP_C PF02841.14 RUS71009.1 - 1.2 8.5 9.3 0.7 9.2 0.2 2.1 1 1 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DDE_Tnp_IS1595 PF12762.7 RUS71010.1 - 3.7e-07 30.3 0.1 1.3e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 ISXO2-like transposase domain Peptidase_A22B PF04258.13 RUS71010.1 - 7.6e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 RUS71010.1 - 0.00096 19.1 0.1 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 PA domain Tetraspanin PF00335.20 RUS71010.1 - 0.11 12.1 2.8 0.23 11.1 2.8 1.4 1 0 0 1 1 1 0 Tetraspanin family Ferric_reduct PF01794.19 RUS71011.1 - 5.6e-15 55.6 2.3 6.5e-14 52.1 0.3 2.2 1 1 1 2 2 2 2 Ferric reductase like transmembrane component RRM_1 PF00076.22 RUS71012.1 - 6.1e-41 138.1 3.0 5.9e-15 54.8 0.1 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 RUS71012.1 - 7e-23 80.4 0.0 1.6e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 RUS71012.1 - 1.9e-05 24.7 0.1 0.45 10.7 0.0 3.8 2 1 1 3 3 3 3 RNA recognition motif RRM_3 PF08777.11 RUS71012.1 - 0.017 15.1 0.6 0.017 15.1 0.6 2.4 3 0 0 3 3 3 0 RNA binding motif Mito_carr PF00153.27 RUS71013.1 - 4.6e-60 199.6 0.2 1.5e-21 76.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SDF PF00375.18 RUS71013.1 - 0.028 13.4 0.0 0.055 12.5 0.0 1.4 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family EB PF01683.18 RUS71015.1 - 2.3e-138 450.4 631.3 8.4e-08 32.4 5.5 49.5 7 7 43 50 50 50 49 EB module Dickkopf_N PF04706.12 RUS71015.1 - 0.01 16.3 3.5 0.01 16.3 3.5 39.7 23 13 19 43 43 43 0 Dickkopf N-terminal cysteine-rich region hEGF PF12661.7 RUS71015.1 - 0.011 16.4 3.7 0.011 16.4 3.7 51.3 54 1 0 54 54 54 0 Human growth factor-like EGF SNF PF00209.18 RUS71016.1 - 3.5e-70 237.2 6.3 4e-70 237.0 6.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 RUS71017.1 - 1.1e-58 199.3 14.0 1.2e-58 199.1 14.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Somatomedin_B PF01033.17 RUS71018.1 - 1e-06 29.0 13.7 1e-06 29.0 13.7 2.3 2 0 0 2 2 2 1 Somatomedin B domain dTDP_sugar_isom PF00908.17 RUS71019.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Homeodomain PF00046.29 RUS71021.1 - 1.8e-19 69.3 9.1 3e-19 68.6 9.1 1.4 1 0 0 1 1 1 1 Homeodomain Lin-8 PF03353.15 RUS71021.1 - 0.038 13.6 5.9 0.057 13.0 5.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 RUS71021.1 - 1.2 9.6 7.6 3.1 8.1 7.6 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like SelK_SelG PF10961.8 RUS71021.1 - 3.2 8.4 19.5 1.5 9.5 5.1 3.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG TFIIA PF03153.13 RUS71021.1 - 6 6.7 23.3 4.9 7.0 21.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3385 PF11865.8 RUS71023.1 - 0.092 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) DUF5496 PF17600.2 RUS71026.1 - 0.00076 19.5 4.4 0.0021 18.1 0.4 3.2 1 1 3 4 4 4 2 Family of unknown function (DUF5496) Amidinotransf PF02274.17 RUS71026.1 - 1 8.4 13.5 19 4.2 1.0 5.0 1 1 3 4 4 4 0 Amidinotransferase EF-hand_1 PF00036.32 RUS71027.1 - 1.2e-21 74.5 6.9 9.4e-07 28.0 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 RUS71027.1 - 2.4e-21 76.0 4.5 5e-13 49.3 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS71027.1 - 1.5e-18 65.1 1.0 0.0002 21.0 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RUS71027.1 - 1.4e-14 52.8 3.0 0.001 18.4 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS71027.1 - 9.3e-12 44.6 4.3 7.2e-06 25.8 0.0 3.4 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS71027.1 - 0.002 18.5 0.2 0.47 10.8 0.0 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS71027.1 - 0.01 15.8 2.8 5.1 7.1 0.1 3.6 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand Arg_decarbox_C PF17944.1 RUS71027.1 - 0.014 15.9 0.0 0.084 13.4 0.0 2.1 2 1 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension EF-hand_9 PF14658.6 RUS71027.1 - 0.065 13.6 0.7 11 6.4 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 RUS71028.1 - 2.3e-22 76.8 7.3 9.4e-07 28.0 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 RUS71028.1 - 2.7e-21 75.8 4.8 4.6e-13 49.4 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS71028.1 - 8.7e-20 68.9 1.0 0.0002 21.0 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RUS71028.1 - 3.8e-15 54.6 3.6 0.00019 20.7 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS71028.1 - 7.3e-12 44.9 4.6 4.5e-06 26.4 0.0 3.4 3 2 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS71028.1 - 0.00076 19.8 0.1 1.6 9.1 0.0 3.2 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS71028.1 - 0.0051 16.7 3.3 4.7 7.2 0.1 3.6 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Arg_decarbox_C PF17944.1 RUS71028.1 - 0.026 15.1 0.0 0.084 13.4 0.0 1.8 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension EF-hand_9 PF14658.6 RUS71028.1 - 0.042 14.2 0.7 11 6.4 0.1 3.4 2 1 1 3 3 3 0 EF-hand domain RcbX PF02341.15 RUS71029.1 - 0.12 12.6 11.8 7.3 6.9 0.6 4.1 1 1 2 4 4 4 0 RbcX protein CEP76-C2 PF15627.6 RUS71029.1 - 2.1 7.9 8.9 71 2.9 3.4 3.9 1 1 1 2 2 2 0 CEP76 C2 domain SWIM PF04434.17 RUS71030.1 - 0.015 15.0 0.9 0.029 14.0 0.9 1.4 1 0 0 1 1 1 0 SWIM zinc finger DDE_Tnp_IS1595 PF12762.7 RUS71031.1 - 2.4e-15 56.9 0.0 4.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 ISXO2-like transposase domain Meis_PKNOX_N PF16493.5 RUS71032.1 - 0.11 12.8 0.0 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 DUF3754 PF12576.8 RUS71033.1 - 0.029 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) HD_4 PF13328.6 RUS71035.1 - 5.5e-21 74.9 0.4 7.7e-21 74.5 0.4 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 RUS71035.1 - 8.5e-07 29.2 1.4 3.5e-06 27.2 1.4 2.0 1 1 0 1 1 1 1 HD domain SAM_PNT PF02198.16 RUS71035.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain FAM184 PF15665.5 RUS71035.1 - 0.11 12.3 3.2 0.2 11.4 2.6 1.8 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Bax1-I PF01027.20 RUS71036.1 - 3.6e-40 138.0 22.0 4.1e-40 137.8 22.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SLATT_1 PF18181.1 RUS71036.1 - 0.99 9.3 2.7 0.74 9.8 0.6 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1003 PF06210.11 RUS71036.1 - 1.2 9.3 4.0 13 5.9 4.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) DUF3487 PF11990.8 RUS71036.1 - 3.2 7.7 10.9 0.61 10.0 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3487) MIOX PF05153.15 RUS71037.1 - 2.6e-105 351.5 0.1 3.1e-105 351.2 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 RUS71037.1 - 0.081 13.2 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 HD domain Neur_chan_LBD PF02931.23 RUS71038.1 - 2.3e-64 216.8 1.4 2.7e-64 216.5 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS71038.1 - 6.5e-33 114.8 0.1 8.8e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MtrE PF04206.12 RUS71038.1 - 0.1 11.9 1.2 0.26 10.6 0.7 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E Neur_chan_memb PF02932.16 RUS71039.1 - 5e-06 26.7 0.0 5.4e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PMC2NT PF08066.12 RUS71039.1 - 0.027 15.1 0.1 0.044 14.5 0.1 1.3 1 0 0 1 1 1 0 PMC2NT (NUC016) domain META PF03724.16 RUS71039.1 - 0.068 13.1 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 META domain DUF2561 PF10812.8 RUS71039.1 - 0.074 13.1 0.0 0.091 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) MecA_N PF05223.11 RUS71039.1 - 0.087 13.1 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain MAJIN PF15077.6 RUS71040.1 - 0.00093 19.1 0.0 0.00093 19.1 0.0 4.2 3 1 3 6 6 6 1 Membrane-anchored junction protein Transposase_22 PF02994.14 RUS71040.1 - 0.11 12.7 4.4 0.082 13.1 1.0 2.5 2 0 0 2 2 2 0 L1 transposable element RBD-like domain NEMP PF10225.9 RUS71040.1 - 0.28 10.8 0.4 0.64 9.6 0.4 1.7 1 0 0 1 1 1 0 NEMP family Reeler PF02014.16 RUS71042.1 - 1.5e-06 29.0 0.0 2.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Reeler domain Neurokinin_B PF03823.14 RUS71043.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Neurokinin B TIR_2 PF13676.6 RUS71044.1 - 0.00024 21.7 0.0 0.00098 19.7 0.0 2.0 2 0 0 2 2 2 1 TIR domain MamL-1 PF09596.10 RUS71044.1 - 0.059 13.6 0.3 0.16 12.3 0.3 1.7 1 0 0 1 1 1 0 MamL-1 domain COR PF16095.5 RUS71045.1 - 1.4e-32 113.1 0.0 2.5e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 RUS71045.1 - 6e-22 78.1 0.0 1.2e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 RUS71045.1 - 3.4e-19 68.3 15.3 3.4e-07 29.9 0.4 4.9 2 1 3 5 5 5 4 Leucine rich repeat MBT PF02820.18 RUS71045.1 - 4.3e-16 59.0 0.0 1.1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 mbt repeat Ras PF00071.22 RUS71045.1 - 1.1e-12 47.9 0.0 2.8e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Ras family LRR_4 PF12799.7 RUS71045.1 - 6.7e-12 45.4 25.5 0.00014 22.1 0.1 6.1 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS71045.1 - 8.4e-05 22.6 18.4 0.98 10.2 1.4 7.2 7 0 0 7 7 5 2 Leucine Rich Repeat MMR_HSR1 PF01926.23 RUS71045.1 - 0.014 15.4 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 RUS71045.1 - 0.025 14.0 0.3 0.11 12.0 0.3 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 RUS71045.1 - 0.044 14.3 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 RUS71045.1 - 0.14 12.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 RUS71045.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.6 RUS71046.1 - 0.0024 17.5 9.1 0.005 16.5 9.1 1.5 1 0 0 1 1 1 1 FAM176 family V_ATPase_I PF01496.19 RUS71046.1 - 0.0037 15.3 1.4 0.0064 14.5 1.4 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Connexin PF00029.19 RUS71046.1 - 0.0086 15.9 4.1 0.015 15.1 4.1 1.3 1 0 0 1 1 1 1 Connexin BUD22 PF09073.10 RUS71046.1 - 0.011 15.1 15.4 0.019 14.3 15.4 1.3 1 0 0 1 1 1 0 BUD22 CLN3 PF02487.17 RUS71046.1 - 0.017 14.2 0.2 0.027 13.6 0.2 1.2 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 RUS71046.1 - 0.02 13.9 1.5 0.04 12.9 1.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 RUS71046.1 - 0.023 13.9 8.7 0.043 13.0 8.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 RUS71046.1 - 0.023 15.1 2.2 0.041 14.3 2.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS71046.1 - 0.04 12.7 3.5 0.068 11.9 3.5 1.3 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 RUS71046.1 - 0.064 13.4 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 RUS71046.1 - 0.087 11.2 0.5 0.16 10.4 0.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_3_Rpc31 PF11705.8 RUS71046.1 - 0.13 12.5 22.4 0.25 11.6 22.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.22 RUS71046.1 - 0.15 11.3 3.2 0.17 11.1 1.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter SpoIIP PF07454.11 RUS71046.1 - 0.15 11.5 14.7 0.61 9.5 11.5 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2956 PF11169.8 RUS71046.1 - 0.53 10.5 7.7 1.3 9.3 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Nop14 PF04147.12 RUS71046.1 - 0.53 8.4 24.3 0.84 7.8 24.3 1.2 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 RUS71046.1 - 0.56 10.4 7.6 1.2 9.2 7.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MAP17 PF15807.5 RUS71046.1 - 1.2 9.4 13.4 2.5 8.4 13.4 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Tim54 PF11711.8 RUS71046.1 - 1.8 7.2 15.6 3.1 6.5 15.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 RUS71046.1 - 2.8 8.2 17.5 6.5 7.1 17.5 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM91_C PF14648.6 RUS71046.1 - 2.8 6.7 7.3 6.4 5.5 2.7 2.2 2 0 0 2 2 2 0 FAM91 C-terminus PTPRCAP PF15713.5 RUS71046.1 - 3.3 8.0 21.1 6.6 7.0 21.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 RUS71046.1 - 3.9 5.4 32.6 5.5 5.0 31.2 1.8 2 0 0 2 2 2 0 DNA polymerase phi EIIBC-GUT_N PF03612.14 RUS71046.1 - 5.4 6.7 5.8 12 5.6 5.8 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 RUS71046.1 - 7.1 5.9 26.3 7.7 5.8 24.7 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Eapp_C PF10238.9 RUS71046.1 - 7.5 6.6 12.1 15 5.6 12.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein AIF_C PF14721.6 RUS71046.1 - 9.2 6.6 10.5 25 5.2 10.5 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.13 RUS71047.1 - 4.4e-21 76.2 5.7 4.4e-21 76.2 5.7 3.8 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4643 PF15485.6 RUS71047.1 - 0.34 10.7 14.0 0.95 9.2 8.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4643) DMPK_coil PF08826.10 RUS71047.1 - 0.62 10.2 6.0 0.081 13.0 1.2 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like TMEM107 PF14995.6 RUS71048.1 - 6.3e-44 149.4 5.9 7.3e-44 149.2 5.9 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF3187 PF11383.8 RUS71049.1 - 0.39 9.9 1.0 8.2 5.5 0.1 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3187) Col_cuticle_N PF01484.17 RUS71050.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain TMCO5 PF14992.6 RUS71050.1 - 0.34 10.4 1.9 20 4.7 0.0 2.6 2 1 1 3 3 3 0 TMCO5 family Globin PF00042.22 RUS71051.1 - 6.2e-19 68.6 0.0 1.1e-18 67.8 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.22 RUS71052.1 - 3.9e-22 78.9 0.0 6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.22 RUS71053.1 - 2e-15 57.3 0.0 4.9e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Globin Globin PF00042.22 RUS71054.1 - 4.2e-09 36.9 0.0 4.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Globin malic PF00390.19 RUS71055.1 - 8.4e-10 38.7 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SE PF08491.10 RUS71055.1 - 0.1 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase SAM_1 PF00536.30 RUS71056.1 - 2.1e-09 37.7 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS71056.1 - 3.6e-09 36.6 0.0 8.9e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS71058.1 - 7.5e-11 42.3 0.0 7.3e-08 32.7 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS71058.1 - 2.3e-07 30.8 0.1 6e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 RUS71058.1 - 0.00049 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS71058.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 SH3 domain SelP_N PF04592.14 RUS71058.1 - 0.58 9.5 10.2 1.5 8.2 10.2 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIE_alpha PF02002.17 RUS71059.1 - 9.8e-27 92.9 4.5 2.6e-26 91.5 4.5 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 RUS71059.1 - 3.7e-18 65.6 2.7 1.3e-17 63.9 2.7 1.9 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 RUS71059.1 - 1.1e-08 34.4 1.2 3e-08 33.0 1.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 RUS71059.1 - 0.039 14.0 0.3 0.08 13.0 0.3 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.6 RUS71059.1 - 0.057 13.2 0.3 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain OrfB_Zn_ribbon PF07282.11 RUS71059.1 - 0.22 11.5 0.7 0.42 10.6 0.7 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain VPS13_C PF16909.5 RUS71062.1 - 3.2e-32 111.7 5.3 1.2e-31 109.9 0.3 2.8 2 2 1 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 RUS71062.1 - 7.1e-05 23.1 0.0 0.00069 19.9 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain SHR-BD PF06650.12 RUS71066.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 DUF2142 PF09913.9 RUS71073.1 - 0.12 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Chorein_N PF12624.7 RUS71074.1 - 8.1e-25 87.2 0.8 1.1e-24 86.8 0.1 1.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 RUS71074.1 - 0.07 12.9 1.1 0.1 12.4 1.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Ribosomal_S7 PF00177.21 RUS71076.1 - 1.8e-35 121.8 0.4 2.3e-35 121.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FMO-like PF00743.19 RUS71079.1 - 5e-61 206.7 0.0 5.5e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS71079.1 - 2e-07 30.6 2.4 0.00081 18.7 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 RUS71080.1 - 2.3e-40 138.5 0.0 3.3e-40 138.0 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 RUS71080.1 - 2.1e-05 24.6 0.0 3.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RUS71080.1 - 3.5e-05 23.2 0.0 9.9e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS71080.1 - 0.0014 18.6 0.8 0.04 13.9 0.8 2.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 RUS71080.1 - 0.0059 15.9 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 RUS71080.1 - 0.013 14.9 0.3 0.017 14.5 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 RUS71080.1 - 0.097 11.8 1.1 1.6 7.8 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 RUS71080.1 - 0.24 10.6 1.1 2.4 7.3 0.7 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 RUS71080.1 - 0.25 11.2 0.4 0.48 10.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 RUS71080.1 - 0.4 10.2 3.1 1.2 8.6 1.2 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 RUS71081.1 - 1.5e-56 190.6 0.0 2.4e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS71081.1 - 8.1e-28 96.7 0.0 9.3e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 RUS71081.1 - 0.00013 22.4 0.1 0.00029 21.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RUS71081.1 - 0.00099 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RUS71081.1 - 0.0022 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 RUS71081.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 RUS71081.1 - 1.1 8.5 3.1 0.93 8.8 0.7 2.0 3 0 0 3 3 3 0 ThiF family FR47 PF08445.10 RUS71082.1 - 3.4e-13 49.4 0.0 6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 RUS71082.1 - 2e-09 37.7 0.0 3.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Gly_acyl_tr_N PF06021.11 RUS71082.1 - 8e-08 32.6 0.0 4.8e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_10 PF13673.7 RUS71082.1 - 4.4e-05 23.4 0.0 6.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RUS71082.1 - 0.00012 22.8 0.0 0.00026 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS71082.1 - 0.00048 20.5 0.1 0.00095 19.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 RUS71082.1 - 0.019 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF1248 PF06852.12 RUS71082.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Bromodomain PF00439.25 RUS71083.1 - 1.2e-16 60.5 1.5 3e-16 59.3 1.5 1.6 1 0 0 1 1 1 1 Bromodomain RIC3 PF15361.6 RUS71084.1 - 2e-27 96.4 0.3 2e-27 96.4 0.3 2.1 2 2 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 Halogen_Hydrol PF10112.9 RUS71084.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein EMC3_TMCO1 PF01956.16 RUS71084.1 - 0.12 12.1 2.8 0.51 10.0 0.0 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SARAF PF06682.12 RUS71084.1 - 1.4 8.5 6.3 1.8 8.2 5.0 2.1 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF148 PF02520.17 RUS71084.1 - 2.5 8.2 7.6 0.52 10.4 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Glyco_hydro_31 PF01055.26 RUS71085.1 - 7.6e-108 361.5 0.6 1e-107 361.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RUS71085.1 - 1.7e-32 112.0 0.1 3.2e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 RUS71085.1 - 5.3e-12 45.4 9.3 5.3e-12 45.4 9.3 1.9 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 RUS71085.1 - 6.2e-08 32.8 0.3 1.6e-07 31.5 0.3 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DNA_pol_A_exo1 PF01612.20 RUS71086.1 - 3.3e-08 33.4 0.0 6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease zf-H2C2_2 PF13465.6 RUS71087.1 - 1.2e-30 104.5 71.7 1.1e-06 28.7 1.1 10.4 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS71087.1 - 5.4e-30 102.2 77.9 3.3e-05 24.1 1.7 9.9 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71087.1 - 9e-26 88.3 71.8 0.0029 18.3 1.6 10.0 9 1 1 10 10 10 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS71087.1 - 2e-15 56.4 68.3 2.4e-05 24.2 1.2 10.5 10 2 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS71087.1 - 5.8e-11 42.4 54.5 0.018 15.3 1.0 10.0 9 1 1 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS71087.1 - 0.00014 22.1 54.7 0.042 14.3 0.8 9.2 10 0 0 10 10 10 4 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS71087.1 - 0.007 16.5 38.2 0.48 10.6 2.2 7.5 4 3 3 7 7 7 2 Zinc ribbon domain DUF4771 PF15995.5 RUS71087.1 - 0.54 10.5 3.7 1.2 9.4 2.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4771) zinc_ribbon_15 PF17032.5 RUS71087.1 - 0.58 10.9 32.7 1.1 10.0 1.0 4.8 1 1 2 4 4 4 0 zinc-ribbon family ADK_lid PF05191.14 RUS71087.1 - 1.3 9.1 26.1 1.9 8.5 0.1 5.2 4 1 0 4 4 4 0 Adenylate kinase, active site lid FpoO PF10621.9 RUS71087.1 - 1.4 9.3 17.7 0.05 13.9 1.5 4.2 2 2 2 4 4 4 0 F420H2 dehydrogenase subunit FpoO zf_UBZ PF18439.1 RUS71087.1 - 1.5 8.5 30.3 19 5.0 0.4 8.4 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 RUS71087.1 - 3.7 7.7 16.7 63 3.7 0.1 5.7 6 0 0 6 6 6 0 Zinc-finger domain FYDLN_acid PF09538.10 RUS71087.1 - 5 7.9 9.2 6.1 7.6 0.2 4.3 1 1 0 4 4 4 0 Protein of unknown function (FYDLN_acid) Aa_trans PF01490.18 RUS71088.1 - 9.9e-58 195.8 29.0 1.2e-57 195.5 29.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF572 PF04502.13 RUS71088.1 - 8 6.0 28.9 11 5.5 28.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1977 PF09320.11 RUS71089.1 - 7e-29 100.2 0.8 1.8e-28 98.8 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 RUS71089.1 - 2.3e-25 88.5 2.2 3.3e-25 88.0 1.0 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 RUS71089.1 - 0.016 15.3 0.3 0.11 12.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 RUS71089.1 - 0.074 13.2 1.0 0.51 10.5 0.1 2.3 2 0 0 2 2 2 0 HemY protein N-terminus RINT1_TIP1 PF04437.13 RUS71090.1 - 9.5e-113 377.7 8.0 9.5e-113 377.7 8.0 2.1 2 1 0 2 2 2 1 RINT-1 / TIP-1 family SF-assemblin PF06705.11 RUS71090.1 - 0.049 13.0 1.7 0.1 11.9 1.7 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin LPP PF04728.13 RUS71090.1 - 0.11 12.8 0.6 2.9 8.4 0.0 3.4 2 1 1 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 RUS71090.1 - 0.31 11.5 3.6 0.55 10.7 0.7 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 RUS71090.1 - 0.67 10.0 3.7 3.4 7.8 0.4 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 RUS71090.1 - 0.68 10.0 5.8 1.1 9.3 0.0 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 RUS71090.1 - 1.7 8.7 5.1 0.29 11.2 0.3 2.2 3 0 0 3 3 3 0 Laminin Domain II UQ_con PF00179.26 RUS71091.1 - 2.6e-47 160.0 0.1 3.2e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS71091.1 - 0.00014 21.6 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-H2C2_2 PF13465.6 RUS71092.1 - 1.1e-28 98.3 56.3 5.5e-09 36.0 1.2 8.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS71092.1 - 1.5e-28 97.6 68.7 6.4e-06 26.3 4.0 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71092.1 - 1.5e-22 78.4 61.3 0.0012 19.5 3.4 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS71092.1 - 5.7e-15 55.2 36.5 6.6e-05 23.1 0.9 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS71092.1 - 4.8e-07 30.0 45.6 0.02 15.3 0.9 8.4 8 1 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS71092.1 - 6.7e-07 29.6 50.5 0.22 11.9 0.2 8.6 3 2 5 8 8 8 5 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 RUS71092.1 - 1.2e-06 28.1 7.6 1.7e-05 24.4 1.6 8.0 8 0 0 8 8 8 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS71092.1 - 1.3e-06 28.3 50.7 0.00033 20.6 0.7 8.0 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2HE PF16278.5 RUS71092.1 - 0.0094 16.4 40.9 1.9 9.0 1.3 8.4 4 2 3 7 7 7 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 RUS71092.1 - 0.011 15.6 25.5 1.7 8.7 0.1 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type NR_Repeat PF14046.6 RUS71092.1 - 0.014 15.5 0.1 0.041 14.0 0.1 1.8 1 0 0 1 1 1 0 Nuclear receptor repeat Spt46 PF17734.1 RUS71092.1 - 0.017 14.9 2.0 0.017 14.9 2.0 4.7 2 1 3 5 5 5 0 Spermatogenesis-associated protein 46 PHF5 PF03660.14 RUS71092.1 - 0.038 14.2 10.8 0.92 9.7 1.0 3.7 2 1 1 3 3 3 0 PHF5-like protein zinc_ribbon_15 PF17032.5 RUS71092.1 - 0.068 13.9 15.6 16 6.4 0.7 4.7 2 1 0 4 4 4 0 zinc-ribbon family DDE_5 PF13546.6 RUS71093.1 - 0.00081 18.8 0.1 0.0014 18.0 0.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease CDO_I PF05995.12 RUS71093.1 - 0.014 14.8 0.2 0.068 12.5 0.0 1.9 1 1 1 2 2 2 0 Cysteine dioxygenase type I C5-epim_C PF06662.13 RUS71094.1 - 1.6e-63 213.6 0.0 2.7e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus DUF2207 PF09972.9 RUS71094.1 - 0.0025 16.7 12.4 0.0037 16.1 12.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4962 PF16332.5 RUS71094.1 - 0.049 12.1 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DUF805 PF05656.14 RUS71094.1 - 6.2 7.3 8.8 17 5.9 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Peptidase_M1 PF01433.20 RUS71095.1 - 1.8e-10 40.8 0.1 4e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RUS71095.1 - 9.8e-05 22.6 0.2 0.0017 18.5 0.0 2.7 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 RUS71095.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats K_oxygenase PF13434.6 RUS71095.1 - 0.097 11.8 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) C4bp_oligo PF18453.1 RUS71096.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha DUF3504 PF12012.8 RUS71097.1 - 3.4e-08 33.5 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3504) SPACA9 PF15120.6 RUS71098.1 - 0.037 13.8 0.5 0.08 12.7 0.1 1.7 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 MFS_1 PF07690.16 RUS71099.1 - 1.9e-54 185.0 48.2 9.9e-52 176.0 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS71099.1 - 0.0023 16.9 30.2 0.015 14.2 12.3 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 RUS71099.1 - 0.013 14.8 13.5 0.074 12.3 13.5 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB BCLP PF12304.8 RUS71099.1 - 0.32 10.5 2.7 0.43 10.1 0.4 2.1 2 0 0 2 2 2 0 Beta-casein like protein DUF4244 PF14029.6 RUS71099.1 - 0.33 10.4 2.3 0.88 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) SURF6 PF04935.12 RUS71100.1 - 4.5e-33 114.7 39.7 4.5e-33 114.7 39.7 2.8 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 RUS71100.1 - 0.0016 19.0 0.1 0.0016 19.0 0.1 6.2 3 2 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 BING4CT PF08149.11 RUS71102.1 - 3.5e-34 116.4 0.0 3.9e-33 113.1 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 RUS71102.1 - 5.9e-05 23.3 0.0 1.4 9.2 0.1 4.6 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS71102.1 - 0.00018 22.2 0.0 0.035 15.0 0.0 4.1 5 1 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RUS71102.1 - 0.00031 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Cofilin_ADF PF00241.20 RUS71103.1 - 4.5e-31 107.2 0.0 1.6e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein 7TM_GPCR_Srw PF10324.9 RUS71104.1 - 4.3e-13 49.2 18.8 7.7e-13 48.4 18.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS71104.1 - 4.2e-07 29.6 18.7 6.3e-07 29.0 18.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_I3 PF04661.12 RUS71104.1 - 0.003 16.7 0.5 0.028 13.6 0.1 2.2 2 0 0 2 2 2 1 Poxvirus I3 ssDNA-binding protein Protocadherin PF08374.11 RUS71104.1 - 0.22 11.5 0.9 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Protocadherin 7tm_1 PF00001.21 RUS71105.1 - 2e-06 27.3 10.5 2e-06 27.3 10.5 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS71105.1 - 1.9e-05 24.4 21.6 3e-05 23.8 20.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4427 PF14468.6 RUS71105.1 - 0.073 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) TMEM154 PF15102.6 RUS71105.1 - 0.095 12.6 3.9 2.9 7.8 1.4 2.7 1 1 1 2 2 2 0 TMEM154 protein family DUF5480 PF17576.2 RUS71105.1 - 2.4 8.2 11.0 1.2 9.1 0.1 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5480) COX6B PF02297.17 RUS71106.1 - 3e-15 56.2 4.0 3e-15 56.2 4.0 1.7 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb COX6B PF02297.17 RUS71108.1 - 3.2e-18 65.7 7.0 5.4e-18 65.0 7.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb rve_2 PF13333.6 RUS71108.1 - 0.083 13.1 0.6 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Integrase core domain DSS1_SEM1 PF05160.13 RUS71108.1 - 0.084 13.0 3.1 4 7.6 1.2 2.3 2 0 0 2 2 2 0 DSS1/SEM1 family DUF4457 PF14652.6 RUS71109.1 - 6.1e-196 650.1 0.1 2.1e-137 457.8 0.1 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 RUS71109.1 - 0.00016 21.7 0.0 4.1 7.4 0.0 4.7 4 0 0 4 4 4 2 Sad1 / UNC-like C-terminal CCDC144C PF14915.6 RUS71110.1 - 2.4e-47 161.5 46.0 2.4e-47 161.5 46.0 8.6 3 3 4 8 8 8 4 CCDC144C protein coiled-coil region ERM PF00769.19 RUS71110.1 - 0.002 18.0 26.0 0.002 18.0 26.0 9.9 3 2 8 11 11 11 1 Ezrin/radixin/moesin family DUF3937 PF13073.6 RUS71111.1 - 1.7e-07 31.3 1.8 0.33 11.1 0.3 4.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3937) DUF1367 PF07105.11 RUS71111.1 - 0.00071 19.3 1.0 9.1 5.9 0.0 3.3 1 1 4 5 5 5 3 Protein of unknown function (DUF1367) UBM PF14377.6 RUS71111.1 - 0.001 18.4 3.1 1e+02 2.5 0.0 6.6 1 1 9 10 10 10 0 Ubiquitin binding region HTH_9 PF08221.11 RUS71111.1 - 0.0034 17.4 0.1 13 6.0 0.0 3.8 1 1 2 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Nrf1_activ_bdg PF10492.9 RUS71111.1 - 0.0038 17.9 13.8 25 5.6 0.1 6.1 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain Transposase_1 PF01359.18 RUS71111.1 - 0.0044 16.8 14.4 6.9 6.6 0.1 5.2 1 1 5 6 6 6 1 Transposase (partial DDE domain) pKID PF02173.17 RUS71111.1 - 0.023 14.1 4.5 1.3e+02 2.2 0.0 6.5 5 2 1 6 6 6 0 pKID domain Condensin2nSMC PF12422.8 RUS71111.1 - 0.038 14.2 1.0 0.11 12.7 1.0 1.8 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit IcmF_C PF06744.12 RUS71111.1 - 0.048 13.3 0.2 23 4.5 0.0 2.7 1 1 3 4 4 4 0 Type VI secretion protein IcmF C-terminal Phage_tail_T PF06223.12 RUS71111.1 - 0.11 13.0 2.7 10 6.7 0.3 2.7 1 1 2 3 3 3 0 Minor tail protein T Spt20 PF12090.8 RUS71111.1 - 0.11 12.1 8.1 11 5.5 0.9 4.1 1 1 3 4 4 4 0 Spt20 family PG_binding_3 PF09374.10 RUS71111.1 - 0.19 12.0 8.8 78 3.6 0.1 5.3 2 1 3 5 5 5 0 Predicted Peptidoglycan domain Alpha_TIF PF02232.15 RUS71111.1 - 4.6 6.2 9.4 5.3 6.0 9.4 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Ank_2 PF12796.7 RUS71112.1 - 6.7e-34 116.3 2.7 1.5e-15 57.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RUS71112.1 - 3.3e-26 90.6 0.9 5.9e-05 23.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 RUS71112.1 - 4.8e-24 84.4 2.7 3.1e-09 37.2 0.0 4.6 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS71112.1 - 5.4e-24 81.7 2.2 7.8e-05 22.8 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RUS71112.1 - 1e-21 76.7 6.4 6.1e-07 29.6 0.6 5.2 1 1 3 5 5 5 5 Ankyrin repeats (many copies) DUF229 PF02995.17 RUS71113.1 - 5.5e-48 163.8 0.2 7.6e-48 163.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) RDM PF11002.8 RUS71114.1 - 1.2e-06 28.4 6.0 49 4.1 0.0 8.1 8 1 1 9 9 9 0 RFPL defining motif (RDM) QRPTase_C PF01729.19 RUS71114.1 - 0.0017 18.2 6.3 14 5.4 0.1 5.4 1 1 7 8 8 8 2 Quinolinate phosphoribosyl transferase, C-terminal domain LEP503 PF15221.6 RUS71114.1 - 0.0018 18.6 3.7 12 6.3 0.0 5.1 3 1 4 7 7 7 1 Lens epithelial cell protein LEP503 DUF4916 PF16262.5 RUS71114.1 - 0.0067 15.9 2.2 1.5 8.3 0.6 4.6 1 1 4 5 5 5 1 Domain of unknown function (DUF4916) DUF1205 PF06722.12 RUS71114.1 - 0.0089 16.1 1.2 2.1 8.5 0.1 3.3 1 1 3 4 4 4 2 Protein of unknown function (DUF1205) tRNA_anti-codon PF01336.25 RUS71114.1 - 0.15 12.0 1.1 39 4.3 0.0 4.3 3 1 0 3 3 3 0 OB-fold nucleic acid binding domain HK97-gp10_like PF04883.12 RUS71114.1 - 0.29 12.1 1.5 24 6.0 0.1 3.1 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component EGF PF00008.27 RUS71115.1 - 2.5 8.5 11.4 0.47 10.8 7.0 2.2 2 0 0 2 2 2 0 EGF-like domain DNA_pol_phi PF04931.13 RUS71116.1 - 0.0027 15.9 35.1 0.0027 15.9 35.1 1.7 2 0 0 2 2 2 1 DNA polymerase phi Tad_C PF09977.9 RUS71117.1 - 0.043 15.0 0.5 0.069 14.4 0.5 1.4 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly ADAM_CR_2 PF17771.1 RUS71118.1 - 0.00097 19.6 0.1 0.00097 19.6 0.1 2.2 2 0 0 2 2 2 1 ADAM cysteine-rich domain 7tm_1 PF00001.21 RUS71119.1 - 2.7e-08 33.5 13.8 6.6e-08 32.2 13.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS71119.1 - 1.6e-06 28.0 14.0 1.6e-06 28.0 14.0 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS71119.1 - 0.00015 21.2 0.5 0.00015 21.2 0.5 2.6 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srw Mid2 PF04478.12 RUS71119.1 - 0.01 15.6 0.2 0.01 15.6 0.2 2.1 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor DoxX_2 PF13564.6 RUS71119.1 - 2.4 8.3 7.0 0.16 12.1 1.0 2.2 3 0 0 3 3 3 0 DoxX-like family Phospholip_B PF04916.13 RUS71120.1 - 2e-142 475.5 0.0 3.4e-130 435.1 0.0 2.0 1 1 1 2 2 2 2 Phospholipase B DUF1664 PF07889.12 RUS71121.1 - 0.0078 16.2 0.7 0.021 14.8 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF2780 PF11075.8 RUS71121.1 - 0.13 12.4 5.5 0.074 13.2 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) DUF4407 PF14362.6 RUS71121.1 - 5.2 6.3 7.1 8.1 5.7 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 RUS71121.1 - 5.5 7.4 19.0 0.11 12.9 7.9 2.4 1 1 1 2 2 2 0 Fez1 BST2 PF16716.5 RUS71121.1 - 9.9 6.8 15.7 26 5.5 8.8 3.7 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 ACBP PF00887.19 RUS71122.1 - 4.1e-32 110.2 0.7 4.6e-32 110.1 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PDZ PF00595.24 RUS71123.1 - 1.3e-29 102.4 0.3 7.9e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS71123.1 - 4.6e-16 58.4 0.4 1.3e-08 34.6 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS71123.1 - 5.3e-12 45.9 0.3 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Ilar_coat PF01787.16 RUS71123.1 - 5.9 6.6 6.5 2.7 7.8 3.4 2.0 2 0 0 2 2 2 0 Ilarvirus coat protein PK PF00224.21 RUS71124.1 - 9.3e-136 452.3 2.8 1.1e-135 452.1 2.8 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 RUS71124.1 - 0.0093 15.1 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 RUS71124.1 - 0.027 13.5 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain ABC_tran PF00005.27 RUS71125.1 - 8.3e-07 29.6 0.0 2e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter RVP PF00077.20 RUS71125.1 - 0.093 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Cyto_heme_lyase PF01265.17 RUS71125.1 - 0.17 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase WD40 PF00400.32 RUS71126.1 - 1.7e-38 129.9 22.4 2.6e-06 28.1 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71126.1 - 6.4e-08 32.8 0.2 0.1 12.9 0.0 4.9 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS71126.1 - 0.0007 18.4 0.3 0.32 9.6 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ntox15 PF15604.6 RUS71126.1 - 0.046 13.8 5.4 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Novel toxin 15 ExsD PF16806.5 RUS71126.1 - 4 7.3 6.2 6.5 6.6 6.2 1.2 1 0 0 1 1 1 0 Antiactivator protein ExsD Somatomedin_B PF01033.17 RUS71127.1 - 0.0008 19.8 11.3 0.0008 19.8 11.3 2.0 2 0 0 2 2 2 1 Somatomedin B domain CoA_binding PF02629.19 RUS71128.1 - 1.2e-08 35.5 0.0 32 5.3 0.0 6.3 1 1 8 9 9 9 0 CoA binding domain SMC_ScpB PF04079.16 RUS71128.1 - 4.1e-07 29.7 1.4 0.79 9.3 0.0 4.8 1 1 5 6 6 6 2 Segregation and condensation complex subunit ScpB LRR_12 PF18837.1 RUS71128.1 - 1.2e-06 28.0 0.8 3.9e+02 0.8 0.0 10.1 13 0 0 13 13 13 0 Leucine-rich repeat RNA_pol_Rpb1_2 PF00623.20 RUS71128.1 - 0.00041 20.6 7.5 22 5.2 0.1 4.8 1 1 5 7 7 7 5 RNA polymerase Rpb1, domain 2 BILBO1_N PF18281.1 RUS71128.1 - 0.011 16.2 5.8 45 4.5 0.1 4.4 1 1 5 6 6 6 0 BILBO1 N-terminal domain DUF5440 PF17509.2 RUS71128.1 - 0.013 15.1 0.4 14 5.3 0.0 4.5 3 1 5 8 8 8 0 Family of unknown function (DUF5440) RVT_1 PF00078.27 RUS71129.1 - 4.2e-21 75.5 0.0 6.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RMI1_N PF08585.12 RUS71130.1 - 0.047 13.4 2.2 0.1 12.3 2.2 1.5 1 0 0 1 1 1 0 RecQ mediated genome instability protein RhoGEF PF00621.20 RUS71131.1 - 5.6e-33 114.7 0.3 1.4e-32 113.4 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 RUS71131.1 - 0.012 15.6 0.2 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 PH domain Sde2_N_Ubi PF13019.6 RUS71131.1 - 0.23 11.3 3.3 0.19 11.5 1.0 2.1 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain adh_short PF00106.25 RUS71132.1 - 3.3e-48 163.7 0.2 4.4e-48 163.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS71132.1 - 4.4e-27 95.2 0.0 6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS71132.1 - 6.6e-16 58.7 0.1 1.5e-15 57.6 0.1 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 RUS71132.1 - 2.9e-08 33.2 0.0 4.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 RUS71132.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 RUS71132.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 RUS71132.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 RUS71132.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Pkinase PF00069.25 RUS71133.1 - 8.9e-74 248.2 0.0 1.3e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS71133.1 - 1.2e-45 155.9 0.0 2.1e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RUS71133.1 - 1.7e-24 85.9 0.1 5.2e-24 84.4 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 RUS71133.1 - 7.3e-08 31.6 0.4 2.3e-07 29.9 0.4 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS71133.1 - 1.6e-06 27.7 0.0 0.00012 21.5 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 RUS71133.1 - 0.0082 16.1 0.0 0.2 11.5 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS71133.1 - 0.011 14.7 0.0 0.049 12.6 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 RUS71133.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Gal_Lectin PF02140.18 RUS71135.1 - 0.14 12.6 4.0 0.33 11.4 4.0 1.7 1 0 0 1 1 1 0 Galactose binding lectin domain zf-C3HC4_2 PF13923.6 RUS71136.1 - 4.4e-07 29.6 12.2 8.6e-07 28.7 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS71136.1 - 4.8e-06 26.3 13.7 9.5e-06 25.4 13.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS71136.1 - 6.6e-06 25.9 12.3 1.4e-05 24.8 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS71136.1 - 4.3e-05 23.5 8.1 5.7e-05 23.1 5.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS71136.1 - 0.0002 21.1 12.8 0.00026 20.8 10.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS71136.1 - 0.00022 21.3 12.9 0.0006 19.9 12.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RUS71136.1 - 0.00084 19.6 14.1 0.0017 18.6 14.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS71136.1 - 0.0034 17.3 11.9 0.0083 16.1 11.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 RUS71136.1 - 0.017 14.9 10.3 0.022 14.5 8.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TSNAXIP1_N PF15739.5 RUS71136.1 - 0.21 12.0 7.5 0.68 10.3 7.5 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus IR1-M PF12185.8 RUS71136.1 - 1 9.4 6.8 4.9 7.2 2.5 2.8 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain zf-C2H2 PF00096.26 RUS71137.1 - 0.00033 20.9 0.7 0.001 19.4 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71137.1 - 0.0092 16.7 0.8 0.0092 16.7 0.8 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger Comm PF15957.5 RUS71137.1 - 0.046 14.1 4.3 0.062 13.7 1.3 2.1 2 0 0 2 2 2 0 Commissureless Amidohydro_1 PF01979.20 RUS71138.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RUS71138.1 - 0.066 12.7 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family XFP_N PF09364.10 RUS71138.1 - 0.18 10.6 0.0 10 4.8 0.0 2.0 1 1 1 2 2 2 0 XFP N-terminal domain Amidohydro_1 PF01979.20 RUS71139.1 - 1.4e-38 133.2 0.0 3.1e-36 125.4 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 RUS71139.1 - 6.2e-06 25.9 0.0 7.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family MOSC PF03473.17 RUS71140.1 - 8.2e-26 90.6 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 RUS71141.1 - 2.5e-25 89.2 0.1 4.3e-16 58.8 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.16 RUS71141.1 - 4.1e-16 59.0 0.0 8.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Ig_3 PF13927.6 RUS71142.1 - 4.8e-57 190.5 0.2 7.8e-13 48.8 0.1 6.0 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RUS71142.1 - 1.4e-50 169.3 0.0 8.4e-12 45.0 0.0 6.9 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS71142.1 - 5.7e-42 141.9 1.2 6.8e-10 39.2 0.0 7.1 7 0 0 7 7 7 5 Immunoglobulin domain ig PF00047.25 RUS71142.1 - 6.1e-36 122.5 0.2 1.2e-07 31.8 0.0 6.3 6 1 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 RUS71142.1 - 3.2e-25 88.3 8.3 2.6e-10 40.5 0.0 5.5 5 0 0 5 5 5 3 Fibronectin type III domain V-set PF07686.17 RUS71142.1 - 1.3e-16 60.7 3.3 0.038 14.2 0.0 9.0 5 3 0 5 5 5 3 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS71142.1 - 2.4e-07 30.9 0.0 0.056 13.7 0.0 4.9 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS71142.1 - 2.5e-06 27.0 0.1 1.8 8.2 0.0 5.0 5 0 0 5 5 5 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS71142.1 - 4.6e-06 26.6 0.0 2.5 8.2 0.0 5.0 5 0 0 5 5 4 1 C17orf99 Ig domain C2-set_2 PF08205.12 RUS71142.1 - 8e-06 25.8 0.1 3.2 7.9 0.0 4.3 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain UL45 PF05473.12 RUS71142.1 - 5.1e-05 23.0 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Ig_5 PF16681.5 RUS71142.1 - 0.00017 22.0 0.0 0.53 10.7 0.0 5.1 6 1 0 6 6 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Lectin_C PF00059.21 RUS71142.1 - 0.00067 20.4 0.0 0.0029 18.3 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain Pur_ac_phosph_N PF16656.5 RUS71142.1 - 0.00078 20.0 0.4 0.0047 17.5 0.0 2.6 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Autoind_bind PF03472.15 RUS71142.1 - 0.0069 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Autoinducer binding domain SusE PF14292.6 RUS71142.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 SusE outer membrane protein Galanin PF01296.18 RUS71144.1 - 0.00027 20.9 24.6 31 4.7 0.0 9.0 2 1 12 14 14 14 2 Galanin Collagen PF01391.18 RUS71144.1 - 0.043 13.6 1.4 4.4 7.2 1.4 2.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF1524 PF07510.11 RUS71144.1 - 0.073 12.9 0.0 0.97 9.3 0.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) CUB PF00431.20 RUS71145.1 - 1.4e-21 76.9 0.1 8.2e-20 71.2 0.0 2.0 2 0 0 2 2 2 2 CUB domain DDE_Tnp_IS1595 PF12762.7 RUS71147.1 - 8.8e-15 55.0 0.6 3.1e-08 33.8 0.2 2.5 1 1 1 2 2 2 2 ISXO2-like transposase domain SSF PF00474.17 RUS71148.1 - 2.2e-36 125.6 21.1 2.8e-36 125.3 21.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Cation_ATPase_C PF00689.21 RUS71148.1 - 2.7 7.7 18.5 0.033 13.9 6.3 3.4 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus preSET_CXC PF18264.1 RUS71149.1 - 0.69 10.4 9.0 1.3 9.5 9.0 1.5 1 0 0 1 1 1 0 CXC domain HLH PF00010.26 RUS71150.1 - 1.4e-17 63.4 0.1 2.7e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HSP70 PF00012.20 RUS71151.1 - 8.3e-51 172.9 2.3 1.9e-31 109.0 0.1 2.0 1 1 1 2 2 2 2 Hsp70 protein LRR_4 PF12799.7 RUS71152.1 - 3.5e-13 49.5 18.4 1.9e-06 28.1 2.9 3.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS71152.1 - 3.6e-10 39.6 1.7 6.4e-09 35.6 0.4 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 RUS71152.1 - 1.2e-07 31.3 9.1 0.00075 19.2 0.8 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 RUS71152.1 - 0.00015 21.6 3.5 8.6 6.7 0.3 4.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 RUS71152.1 - 0.049 14.2 5.0 18 6.3 0.3 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat RPE65 PF03055.15 RUS71153.1 - 8.5e-32 110.9 0.0 8.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 RUS71154.1 - 1.4e-27 97.1 0.0 1.7e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GlcNAc_2-epim PF07221.11 RUS71156.1 - 3.3e-45 154.8 0.1 5e-45 154.2 0.1 1.2 1 1 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 RUS71156.1 - 0.0096 15.5 0.3 4 6.8 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 LANC_like PF05147.13 RUS71156.1 - 0.0098 14.5 0.0 0.13 10.8 0.0 2.2 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 RUS71156.1 - 0.037 13.1 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 RUS71156.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Hydrolase_6 PF13344.6 RUS71157.1 - 3.5e-16 59.2 0.0 6.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS71157.1 - 2.9e-15 56.1 0.1 5.7e-14 51.9 0.1 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 RUS71157.1 - 1.4e-05 25.5 0.2 9.1e-05 22.8 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RUS71157.1 - 6.8e-05 23.0 0.0 0.0015 18.6 0.0 2.3 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UCR_TM PF02921.14 RUS71158.1 - 2.7e-21 75.8 0.6 4.7e-21 75.0 0.6 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 RUS71158.1 - 6.9e-12 45.1 0.0 2e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Ubiq-Cytc-red_N PF09165.10 RUS71158.1 - 2.7e-07 31.4 6.5 2.7e-07 31.4 6.5 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DUF3918 PF13056.6 RUS71158.1 - 1.3 8.7 3.0 1.1 8.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) CTNNBL PF08216.11 RUS71159.1 - 3.1e-35 120.5 2.3 1.2e-34 118.6 2.3 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Leptin PF02024.15 RUS71159.1 - 0.0069 16.2 3.5 0.19 11.5 0.2 2.6 2 0 0 2 2 2 2 Leptin Arm PF00514.23 RUS71159.1 - 0.11 12.6 2.1 9.3 6.5 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat zf-CCCH_4 PF18044.1 RUS71160.1 - 8.6e-08 31.8 3.1 1.3e-07 31.2 3.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RUS71160.1 - 1.7e-05 24.7 5.0 2.9e-05 24.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RUS71160.1 - 0.0007 19.4 2.0 0.0012 18.6 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RUS71160.1 - 0.0028 18.3 1.5 0.0054 17.4 0.1 2.3 2 0 0 2 2 2 1 Torus domain CECR6_TMEM121 PF14997.6 RUS71161.1 - 1.1e-47 162.4 10.8 1.9e-47 161.6 10.8 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF2921 PF11145.8 RUS71161.1 - 0.027 12.3 0.2 0.037 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) TOM13 PF08219.11 RUS71161.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.6 3 0 0 3 3 3 0 Outer membrane protein TOM13 DUF1275 PF06912.11 RUS71161.1 - 1 9.3 7.7 3.5 7.5 7.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) DUF202 PF02656.15 RUS71161.1 - 1.9 9.0 6.5 8.6 6.9 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) UPF0242 PF06785.11 RUS71163.1 - 0.0095 16.1 4.5 0.013 15.6 4.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 RUS71163.1 - 4.7 6.5 5.4 6.9 5.9 5.4 1.2 1 0 0 1 1 1 0 FAM76 protein HOK_GEF PF01848.16 RUS71164.1 - 8.9e-06 25.0 8.6 0.79 9.2 0.4 5.1 2 2 3 5 5 5 5 Hok/gef family HTH_Mga PF08280.11 RUS71164.1 - 0.00054 19.9 0.6 0.53 10.4 0.2 2.4 2 0 0 2 2 2 2 M protein trans-acting positive regulator (MGA) HTH domain SPT_ssu-like PF11779.8 RUS71164.1 - 0.014 15.0 1.8 0.62 9.7 0.3 3.4 3 2 1 5 5 5 0 Small subunit of serine palmitoyltransferase-like HTH_9 PF08221.11 RUS71164.1 - 0.024 14.7 0.0 67 3.7 0.0 3.9 2 2 1 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AKAP7_NLS PF10469.9 RUS71165.1 - 7.8e-40 137.0 0.0 1.9e-38 132.5 0.0 2.1 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 RUS71165.1 - 8.4e-24 84.1 0.5 1.9e-23 83.0 0.3 1.8 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain 2_5_RNA_ligase2 PF13563.6 RUS71165.1 - 4.7e-07 29.8 0.3 9.7e-06 25.6 0.1 2.2 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily RWD PF05773.22 RUS71165.1 - 6.6e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain CDC45 PF02724.14 RUS71165.1 - 4.2 5.5 5.8 0.77 8.0 1.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Cadherin_C_2 PF16492.5 RUS71166.1 - 0.018 15.8 0.0 0.13 13.1 0.0 2.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF5113 PF17140.4 RUS71166.1 - 0.064 13.1 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Orf78 PF06024.12 RUS71166.1 - 0.11 12.8 1.3 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Dehalogenase PF13486.6 RUS71166.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.7 3 0 0 3 3 3 0 Reductive dehalogenase subunit SID-1_RNA_chan PF13965.6 RUS71166.1 - 0.23 9.8 0.0 0.23 9.8 0.0 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Syndecan PF01034.20 RUS71166.1 - 7.2 6.6 5.0 21 5.1 5.0 1.7 1 0 0 1 1 1 0 Syndecan domain MFS_1 PF07690.16 RUS71167.1 - 6.9e-08 31.8 3.0 8.2e-08 31.5 3.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS71167.1 - 3.7e-06 26.1 0.3 3.9e-06 26.0 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter UPF0227 PF05728.12 RUS71167.1 - 0.24 11.3 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MFS_1 PF07690.16 RUS71168.1 - 4.7e-30 104.7 40.3 2.1e-25 89.4 15.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS71168.1 - 2.5e-28 99.2 21.0 3.7e-17 62.3 3.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter RPE65 PF03055.15 RUS71169.1 - 4.3e-73 247.1 0.0 6e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HEAT_2 PF13646.6 RUS71171.1 - 4e-30 104.1 9.7 3.4e-09 37.0 0.5 5.1 3 1 4 7 7 7 6 HEAT repeats HEAT PF02985.22 RUS71171.1 - 9.1e-10 37.9 7.5 0.63 10.4 0.1 7.2 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 RUS71171.1 - 0.00014 22.3 0.9 0.97 10.0 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat RICTOR_V PF14668.6 RUS71171.1 - 0.067 13.4 0.1 1.4 9.2 0.0 3.0 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Lectin_C PF00059.21 RUS71173.1 - 2.9e-11 44.1 0.0 5.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS71173.1 - 0.0027 17.6 0.4 0.0069 16.3 0.4 1.7 1 0 0 1 1 1 1 PAN domain MFS_1 PF07690.16 RUS71174.1 - 1.8e-32 112.7 40.9 1.8e-32 112.7 40.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 RUS71174.1 - 1.9e-08 34.0 32.9 2.8e-07 30.2 11.7 3.0 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB FAM176 PF14851.6 RUS71174.1 - 1 9.0 10.8 7.7 6.2 0.2 2.6 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 RUS71174.1 - 2.2 8.1 9.7 3.5 7.5 9.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Scramblase PF03803.15 RUS71175.1 - 1e-68 231.0 0.0 1.4e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Scramblase Lectin_C PF00059.21 RUS71176.1 - 5.9e-13 49.5 0.0 7.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Ribosomal_S19e PF01090.19 RUS71177.1 - 3.3e-56 188.8 0.0 3.9e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e CarboxypepD_reg PF13620.6 RUS71178.1 - 3.1e-51 171.6 4.7 4.7e-09 36.4 0.0 9.6 9 0 0 9 9 9 7 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 RUS71178.1 - 4.2e-23 81.8 0.0 9.2e-06 25.8 0.0 7.5 8 1 0 8 8 8 5 Protein of unknown function (DUF2012) SdrD_B PF17210.3 RUS71178.1 - 7e-22 77.8 7.5 0.0034 17.6 0.2 9.1 9 0 0 9 9 9 6 SdrD B-like domain CarbopepD_reg_2 PF13715.6 RUS71178.1 - 1.9e-20 72.6 11.0 1.5e-08 34.5 0.2 8.4 8 0 0 8 8 8 5 CarboxypepD_reg-like domain SpaA PF17802.1 RUS71178.1 - 4e-12 46.3 0.2 1.2 9.6 0.2 7.3 7 0 0 7 7 7 2 Prealbumin-like fold domain fn3_3 PF14686.6 RUS71178.1 - 3.8e-11 42.6 3.9 0.031 14.1 0.0 7.7 9 0 0 9 9 9 2 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.13 RUS71178.1 - 6.9e-07 29.1 0.7 0.82 9.7 0.0 6.0 6 0 0 6 6 6 1 Y_Y_Y domain Big_1 PF02369.16 RUS71178.1 - 2.3e-05 24.3 1.7 0.25 11.4 0.1 4.9 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 1) DUF2846 PF11008.8 RUS71178.1 - 7.6e-05 22.7 0.5 4.9 7.2 0.0 5.3 5 0 0 5 5 5 1 Protein of unknown function (DUF2846) EMP24_GP25L PF01105.24 RUS71178.1 - 0.0054 16.7 1.5 2.1 8.2 0.0 3.6 5 0 0 5 5 5 1 emp24/gp25L/p24 family/GOLD phage_tail_N PF08400.10 RUS71178.1 - 0.094 12.7 1.0 19 5.2 0.0 3.3 3 0 0 3 3 3 0 Prophage tail fibre N-terminal PPC PF04151.15 RUS71178.1 - 0.34 12.1 1.8 22 6.2 0.0 4.4 3 1 0 3 3 2 0 Bacterial pre-peptidase C-terminal domain SR-25 PF10500.9 RUS71178.1 - 0.41 10.2 7.0 0.69 9.5 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ig_3 PF13927.6 RUS71179.1 - 9.2e-18 64.6 0.0 2.3e-06 28.1 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS71179.1 - 4.7e-13 49.0 0.0 3.1e-05 24.0 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.21 RUS71179.1 - 6.1e-10 39.3 0.3 1.8e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.6 RUS71179.1 - 3.7e-09 36.8 0.2 0.0017 18.7 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS71179.1 - 1.1e-08 35.1 0.0 0.0092 16.1 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS71179.1 - 1.1e-05 25.5 0.2 0.00027 21.1 0.0 3.1 3 1 0 3 3 3 1 Immunoglobulin V-set domain DUF347 PF03988.12 RUS71179.1 - 0.0042 17.2 1.1 0.0098 16.1 1.1 1.6 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Adeno_E3_CR2 PF02439.15 RUS71179.1 - 0.011 15.5 3.1 0.017 14.8 3.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 RUS71179.1 - 0.012 14.5 1.8 0.012 14.5 1.8 1.9 3 0 0 3 3 3 0 Giardia variant-specific surface protein Amnionless PF14828.6 RUS71179.1 - 0.051 12.4 0.3 0.077 11.8 0.3 1.2 1 0 0 1 1 1 0 Amnionless ASFV_J13L PF05568.11 RUS71179.1 - 0.091 12.5 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Izumo-Ig PF16706.5 RUS71179.1 - 0.11 12.6 0.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS71179.1 - 0.21 11.8 0.5 3.5 8.0 0.1 2.8 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain DUF963 PF06131.11 RUS71179.1 - 1.4 8.4 7.2 10 5.6 0.4 3.0 1 1 2 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Syndecan PF01034.20 RUS71179.1 - 6.1 6.9 5.6 13 5.8 5.6 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2781 PF10914.8 RUS71180.1 - 1.3e-47 161.9 10.2 1.5e-47 161.7 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) NDUF_B5 PF09781.9 RUS71180.1 - 0.049 13.2 0.3 0.049 13.2 0.3 1.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Na_sulph_symp PF00939.19 RUS71181.1 - 2e-81 274.4 17.4 5.1e-45 154.4 9.0 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS71181.1 - 4.5e-33 114.7 32.2 5.2e-18 65.3 0.1 3.2 2 1 1 3 3 3 3 Citrate transporter DcuC PF03606.15 RUS71181.1 - 6.6e-05 21.6 6.3 6.6e-05 21.6 6.3 2.6 4 0 0 4 4 4 1 C4-dicarboxylate anaerobic carrier Hum_adeno_E3A PF05393.11 RUS71181.1 - 0.0037 17.2 0.6 0.28 11.2 0.1 2.8 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein L_HMGIC_fpl PF10242.9 RUS71182.1 - 8.2e-39 133.7 9.7 9.9e-39 133.4 9.7 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 RUS71182.1 - 0.023 14.5 9.8 0.057 13.2 9.8 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TPR_2 PF07719.17 RUS71183.1 - 3.8e-26 89.0 16.6 0.00063 19.7 0.1 9.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 RUS71183.1 - 2e-23 81.2 12.2 0.00074 19.2 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 RUS71183.1 - 1.3e-21 76.8 11.7 0.00023 21.6 0.0 7.1 5 3 2 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 RUS71183.1 - 5.4e-19 66.8 8.9 0.02 15.1 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71183.1 - 1.2e-18 67.5 2.3 4.9e-05 23.9 0.0 6.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS71183.1 - 7.3e-18 63.7 9.2 0.012 16.4 0.1 8.4 6 3 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 RUS71183.1 - 1.3e-14 54.2 15.5 0.02 15.2 0.0 6.9 7 1 0 7 7 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS71183.1 - 4.8e-13 49.2 27.8 0.0084 16.3 0.6 7.5 4 2 4 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RUS71183.1 - 2.2e-12 46.4 0.8 0.38 10.5 0.0 6.4 6 0 0 6 6 6 3 TPR repeat TPR_6 PF13174.6 RUS71183.1 - 5.4e-11 42.4 6.6 0.32 11.7 0.0 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS71183.1 - 6.4e-11 41.5 10.2 0.048 13.7 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 RUS71183.1 - 2.2e-08 33.7 10.9 0.1 11.8 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 RUS71183.1 - 4.1e-05 23.4 4.5 5.6 6.6 0.1 4.9 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 RUS71183.1 - 5e-05 23.8 12.4 0.39 11.1 0.1 5.8 5 2 1 6 6 6 2 Bacterial transcriptional activator domain ChAPs PF09295.10 RUS71183.1 - 8.1e-05 21.8 3.4 0.0015 17.6 0.0 3.1 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 RUS71183.1 - 0.003 17.3 6.7 0.14 11.9 0.1 5.1 5 1 1 6 6 6 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 RUS71183.1 - 0.013 15.6 10.4 0.075 13.2 1.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS71183.1 - 0.024 14.5 6.9 6 6.9 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS71183.1 - 0.029 14.4 11.0 0.065 13.3 0.5 4.6 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ERAP1_C PF11838.8 RUS71183.1 - 0.033 13.7 0.1 0.091 12.3 0.1 1.8 1 0 0 1 1 1 0 ERAP1-like C-terminal domain YfiO PF13525.6 RUS71183.1 - 0.15 11.8 8.0 9.2 5.9 0.0 4.3 5 1 0 5 5 4 0 Outer membrane lipoprotein PPR PF01535.20 RUS71183.1 - 0.17 12.2 7.9 15 6.1 0.1 5.6 7 0 0 7 7 5 0 PPR repeat HrpB1_HrpK PF09613.10 RUS71183.1 - 0.19 11.4 2.2 4.3 7.0 0.1 3.5 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 RUS71183.1 - 0.31 11.8 4.0 37 5.4 0.0 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RUS71183.1 - 8.1 7.1 20.8 64 4.3 0.3 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat LrgA PF03788.14 RUS71184.1 - 0.5 10.4 5.8 0.11 12.4 2.2 1.6 2 0 0 2 2 2 0 LrgA family zf-C2H2 PF00096.26 RUS71189.1 - 1.4e-18 66.2 18.8 0.00024 21.4 0.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71189.1 - 1.3e-11 44.3 16.9 0.012 16.4 0.5 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS71189.1 - 1.8e-06 28.2 5.9 0.0017 18.6 1.7 3.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 RUS71189.1 - 5.1e-05 23.5 23.0 0.013 15.9 0.2 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS71189.1 - 0.00074 19.2 1.3 1.4 8.7 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS71189.1 - 0.0049 16.8 0.1 0.0049 16.8 0.1 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RUS71189.1 - 0.0073 16.5 7.3 1.2 9.2 0.0 4.1 3 1 1 4 4 4 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 RUS71189.1 - 0.02 15.1 6.3 3 8.2 0.6 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 RUS71189.1 - 0.085 13.5 10.2 21 5.8 0.3 4.4 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RUS71189.1 - 0.23 11.3 3.3 15 5.4 0.2 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type CHORD PF04968.12 RUS71189.1 - 0.28 11.9 10.4 7.8 7.3 0.4 4.1 2 1 2 4 4 4 0 CHORD zf-DNA_Pol PF08996.10 RUS71189.1 - 0.29 10.8 5.3 1.6 8.4 5.4 2.0 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Ogr_Delta PF04606.12 RUS71189.1 - 0.45 10.5 5.6 3.2 7.8 0.1 3.2 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger IBR PF01485.21 RUS71189.1 - 0.59 10.4 10.6 2.4 8.4 4.7 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF3915 PF13054.6 RUS71191.1 - 0.13 12.3 6.6 0.22 11.5 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sec1 PF00995.23 RUS71192.1 - 8.6e-122 408.3 0.8 9.7e-122 408.1 0.8 1.0 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.20 RUS71192.1 - 0.046 14.2 3.1 2.2 8.8 0.0 3.4 3 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3417 PF11897.8 RUS71192.1 - 0.73 10.3 3.4 2 8.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) Methyltransf_25 PF13649.6 RUS71193.1 - 8.7e-10 39.2 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RUS71193.1 - 4.7e-08 32.8 0.0 7.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RUS71193.1 - 1.9e-07 31.0 0.0 3.7e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS71193.1 - 7.5e-07 29.7 0.0 2.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS71193.1 - 1.6e-06 28.1 0.0 9e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 RUS71193.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 RUS71193.1 - 0.00092 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RUS71193.1 - 0.0026 18.5 0.0 0.006 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RUS71193.1 - 0.0071 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 RUS71193.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 RUS71193.1 - 0.056 12.9 0.1 0.099 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 RUS71193.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DcpS_C PF11969.8 RUS71194.1 - 1.3e-26 93.3 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RUS71194.1 - 1.7e-09 38.3 1.5 6.1e-09 36.5 1.5 1.7 1 1 0 1 1 1 1 HIT domain CDH PF02611.15 RUS71194.1 - 0.019 14.6 0.8 0.064 12.9 0.8 1.8 1 1 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Pox_A9 PF04835.12 RUS71194.1 - 0.19 11.9 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 A9 protein conserved region ATG101 PF07855.12 RUS71195.1 - 4.2e-38 130.7 0.1 6.1e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 Glyco_transf_10 PF00852.19 RUS71196.1 - 2.1e-44 151.3 0.2 3e-44 150.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS71196.1 - 4.4e-10 40.0 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal m04gp34like PF12216.8 RUS71196.1 - 0.024 14.2 0.3 0.037 13.6 0.3 1.3 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.6 RUS71196.1 - 0.067 14.1 0.5 0.14 13.0 0.5 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0258 PF06789.12 RUS71196.1 - 0.91 9.6 4.5 2 8.5 4.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF4834 PF16118.5 RUS71196.1 - 0.93 10.5 4.0 2.2 9.3 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RIFIN PF02009.16 RUS71196.1 - 1.1 9.1 5.7 1.4 8.8 5.7 1.2 1 0 0 1 1 1 0 Rifin HSP20 PF00011.21 RUS71197.1 - 3.9e-17 62.3 0.0 6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS71197.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4461 PF14688.6 RUS71198.1 - 1.2e-28 100.9 0.3 1.3e-28 100.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) PBP PF01161.20 RUS71199.1 - 1.1e-08 35.5 0.0 2.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RVT_1 PF00078.27 RUS71200.1 - 2e-25 89.7 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 RUS71200.1 - 7.1e-06 25.5 3.8 1.5e-05 24.4 3.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS71200.1 - 1.9e-05 24.5 5.5 3.6e-05 23.6 5.5 1.4 1 0 0 1 1 1 1 PHD-finger Ank_2 PF12796.7 RUS71201.1 - 2e-46 156.5 0.1 9.1e-10 39.0 0.0 5.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS71201.1 - 1e-39 134.4 1.2 7.4e-09 36.0 0.0 7.3 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS71201.1 - 1.6e-35 117.1 0.7 0.001 19.4 0.0 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS71201.1 - 2.1e-34 117.1 6.6 2.7e-07 30.7 0.0 7.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS71201.1 - 5.2e-31 105.7 11.0 9e-05 22.8 0.0 9.5 9 1 1 10 10 10 6 Ankyrin repeat SAM_1 PF00536.30 RUS71201.1 - 9.7e-11 42.0 0.1 2.9e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS71201.1 - 3.7e-07 30.2 0.1 8.8e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 RUS71201.1 - 0.0013 18.8 0.0 0.0043 17.1 0.0 1.9 1 0 0 1 1 1 1 IGR protein motif F-box-like PF12937.7 RUS71202.1 - 3.3e-10 39.7 8.1 1.7e-09 37.4 4.4 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS71202.1 - 6.5e-10 38.6 2.6 6.5e-10 38.6 2.6 2.4 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 RUS71202.1 - 0.014 15.0 0.4 0.044 13.3 0.4 1.8 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 RUS71202.1 - 0.65 10.5 9.2 15 6.2 4.9 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) RNase_Zc3h12a PF11977.8 RUS71203.1 - 1.2e-48 164.8 0.0 2.6e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain RNase_Zc3h12a PF11977.8 RUS71204.1 - 1.7e-43 148.1 0.0 1.8e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF5615 PF18480.1 RUS71204.1 - 0.033 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Innexin PF00876.18 RUS71205.1 - 4.9e-88 295.8 5.8 5.7e-88 295.6 5.8 1.0 1 0 0 1 1 1 1 Innexin Herpes_UL46 PF03387.14 RUS71205.1 - 0.026 13.3 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL46 protein F5_F8_type_C PF00754.25 RUS71206.1 - 2.4e-07 30.9 0.0 4.2e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 F5/8 type C domain 7tm_1 PF00001.21 RUS71207.1 - 8.3e-39 133.5 15.7 1.1e-36 126.5 15.7 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1218 PF06749.12 RUS71207.1 - 0.013 16.0 5.7 2.7 8.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) YukC PF10140.9 RUS71207.1 - 1.5 7.6 3.6 0.3 9.9 0.1 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC DUF2207 PF09972.9 RUS71207.1 - 5.3 5.7 7.6 1.4 7.6 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TPR_1 PF00515.28 RUS71208.1 - 1.6e-35 119.4 0.1 2.1e-09 36.8 1.3 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS71208.1 - 3e-29 98.7 1.3 3.1e-07 30.0 0.7 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71208.1 - 7.1e-24 84.2 0.1 6.7e-10 39.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS71208.1 - 2e-22 77.4 1.9 0.00018 21.4 0.6 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RUS71208.1 - 4.1e-20 71.2 1.4 4.2e-06 26.3 0.9 6.4 1 1 5 6 6 6 4 TPR repeat TPR_17 PF13431.6 RUS71208.1 - 6.5e-18 63.8 0.4 0.0088 16.4 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 RUS71208.1 - 1.4e-14 54.3 0.1 1.1e-05 25.9 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS71208.1 - 3.3e-14 52.4 0.1 0.097 13.5 0.1 5.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 RUS71208.1 - 2.5e-13 50.1 5.6 0.00027 21.2 1.6 5.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 RUS71208.1 - 1.7e-09 37.7 0.0 0.0062 16.7 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS71208.1 - 3.7e-09 36.6 3.2 6.9 7.5 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS71208.1 - 3.2e-08 33.0 1.1 1.3 9.2 0.3 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS71208.1 - 6.4e-08 32.7 7.4 0.00045 20.4 3.3 3.3 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RUS71208.1 - 2.2e-06 27.1 0.5 0.01 15.1 0.5 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 RUS71208.1 - 0.00048 19.2 5.4 0.22 10.4 1.2 2.9 1 1 2 3 3 3 3 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 RUS71208.1 - 0.0014 18.4 4.4 6.6 6.7 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 RUS71208.1 - 0.005 17.2 2.5 0.022 15.1 0.2 2.9 2 1 1 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS71208.1 - 0.0075 15.7 1.6 0.33 10.3 0.0 2.6 1 1 2 3 3 3 2 MalT-like TPR region ChAPs PF09295.10 RUS71208.1 - 0.015 14.4 0.4 0.096 11.7 0.0 2.3 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 RUS71208.1 - 0.022 14.5 1.6 4.6 6.9 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain FAT PF02259.23 RUS71208.1 - 0.031 13.5 3.2 3.1 6.9 0.3 2.9 1 1 2 3 3 3 0 FAT domain PPTA PF01239.22 RUS71208.1 - 0.037 13.8 0.2 1.9 8.3 0.1 3.2 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat Epimerase_2 PF02350.19 RUS71208.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF5113 PF17140.4 RUS71208.1 - 0.23 11.2 3.1 1.1 9.0 1.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5113) zf-H2C2_2 PF13465.6 RUS71209.1 - 6.7e-33 111.7 49.7 2.7e-06 27.5 1.2 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS71209.1 - 6.7e-32 108.2 53.6 1.2e-06 28.6 2.2 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71209.1 - 2e-22 77.9 47.8 0.00073 20.2 3.0 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS71209.1 - 1.9e-11 43.6 44.9 0.0002 21.2 3.7 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS71209.1 - 2.1e-09 37.4 34.5 0.13 12.5 0.1 6.8 6 1 1 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS71209.1 - 1.5e-06 28.4 32.5 0.057 13.8 0.4 6.7 6 0 0 6 6 6 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS71209.1 - 2e-05 24.6 20.3 0.072 13.2 1.2 4.7 3 2 1 4 4 4 3 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RUS71209.1 - 3.7e-05 24.4 16.5 0.23 12.2 0.8 3.2 2 1 1 3 3 3 3 zinc-ribbon family zf-Di19 PF05605.12 RUS71209.1 - 0.00024 21.3 32.6 0.046 14.0 6.9 4.2 2 2 2 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RUS71209.1 - 0.00074 19.1 18.5 0.22 11.1 0.1 6.4 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 RUS71209.1 - 0.0026 17.5 11.8 1.2 8.9 0.0 4.8 1 1 3 5 5 5 1 GAGA factor zf-MYST PF17772.1 RUS71209.1 - 0.0074 15.9 17.7 0.52 10.0 0.2 5.0 3 3 3 6 6 6 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 RUS71209.1 - 0.0077 16.3 21.1 0.16 12.1 1.8 5.3 3 3 2 5 5 5 2 Sec23/Sec24 zinc finger ADK_lid PF05191.14 RUS71209.1 - 0.011 15.7 24.8 0.086 12.8 1.5 4.6 2 2 2 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 RUS71209.1 - 0.014 15.2 22.8 0.38 10.6 0.3 5.2 5 0 0 5 5 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 RUS71209.1 - 0.014 15.2 12.6 3 7.8 0.1 4.8 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) FYVE PF01363.21 RUS71209.1 - 0.029 14.5 28.8 0.5 10.5 6.9 3.8 1 1 1 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.16 RUS71209.1 - 0.099 12.8 33.6 0.53 10.5 1.9 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger FYDLN_acid PF09538.10 RUS71209.1 - 0.13 12.9 9.8 19 6.0 1.3 4.7 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF2489 PF10675.9 RUS71209.1 - 0.14 12.0 0.1 4.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF2180 PF09947.9 RUS71209.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.2 2 1 2 4 4 2 0 Uncharacterized protein conserved in archaea (DUF2180) BolA PF01722.18 RUS71209.1 - 0.24 11.7 3.1 5.5 7.3 0.0 3.0 1 1 1 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.7 RUS71209.1 - 0.25 11.7 33.3 2.1 8.7 4.3 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 RUS71209.1 - 0.36 10.7 18.2 2.1 8.2 0.3 4.8 4 0 0 4 4 4 0 Zinc knuckle Zf_RING PF16744.5 RUS71209.1 - 0.37 10.9 23.9 0.15 12.2 0.7 5.6 1 1 5 6 6 6 0 KIAA1045 RING finger OrfB_Zn_ribbon PF07282.11 RUS71209.1 - 0.65 10.0 0.0 0.65 10.0 0.0 5.0 2 1 4 6 6 6 0 Putative transposase DNA-binding domain zf-H2C2_5 PF13909.6 RUS71209.1 - 0.8 9.5 0.1 0.8 9.5 0.1 6.5 8 1 0 8 8 4 0 C2H2-type zinc-finger domain zf-RING_7 PF02591.15 RUS71209.1 - 0.96 9.7 0.1 0.96 9.7 0.1 3.6 5 0 0 5 5 4 0 C4-type zinc ribbon domain XPA_N PF01286.18 RUS71209.1 - 0.97 9.5 21.4 27 4.9 0.0 6.3 6 0 0 6 6 6 0 XPA protein N-terminal zf_ZIC PF18366.1 RUS71209.1 - 1.5 9.0 20.2 5.8 7.1 1.0 5.0 3 2 2 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 RUS71209.1 - 1.7 9.4 23.2 3.9 8.2 0.5 5.0 1 1 0 2 2 1 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 RUS71209.1 - 1.7 9.0 18.4 14 6.1 0.2 5.7 6 0 0 6 6 6 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 RUS71209.1 - 2 8.4 24.0 3.3 7.7 2.5 4.3 3 2 0 3 3 3 0 SprT-like zinc ribbon domain C1_2 PF03107.16 RUS71209.1 - 2.4 8.5 32.7 0.43 10.9 1.8 5.9 2 2 2 5 5 5 0 C1 domain Rep_fac-A_C PF08646.10 RUS71209.1 - 3.5 7.3 13.0 1.3 8.8 1.2 3.2 1 1 1 3 3 3 0 Replication factor-A C terminal domain Acetone_carb_G PF08882.11 RUS71209.1 - 4.1 7.6 7.2 21 5.3 0.1 3.1 2 2 1 3 3 3 0 Acetone carboxylase gamma subunit Zn_Tnp_IS1595 PF12760.7 RUS71209.1 - 5.4 7.1 23.9 0.07 13.1 1.3 4.1 3 1 1 4 4 4 0 Transposase zinc-ribbon domain CpXC PF14353.6 RUS71209.1 - 5.7 7.0 21.7 0.46 10.6 2.0 4.9 1 1 4 5 5 5 0 CpXC protein SRCR_2 PF15494.6 RUS71210.1 - 0.061 13.9 3.1 0.093 13.3 1.7 2.1 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain FSA_C PF10479.9 RUS71210.1 - 8.7 4.3 22.7 8.8 4.3 22.7 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AMOP PF03782.17 RUS71211.1 - 0.0014 18.8 15.3 0.091 12.9 1.0 3.9 1 1 3 4 4 4 3 AMOP domain DUF1091 PF06477.13 RUS71211.1 - 0.0043 17.5 1.3 5.3 7.6 0.2 3.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1091) DUF2158 PF09926.9 RUS71211.1 - 0.049 13.4 0.4 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) DUF745 PF05335.13 RUS71213.1 - 0.0012 18.6 15.6 0.0012 18.6 15.6 6.7 3 1 2 7 7 7 2 Protein of unknown function (DUF745) YpjP PF14005.6 RUS71215.1 - 0.00035 20.6 5.2 6.3 6.9 0.3 4.0 1 1 3 4 4 4 2 YpjP-like protein Csm1 PF12539.8 RUS71215.1 - 0.00051 20.6 7.2 9.3 7.0 4.4 4.0 1 1 1 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 GAS PF13851.6 RUS71215.1 - 0.025 13.9 0.1 2 7.7 0.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF916 PF06030.12 RUS71215.1 - 0.11 12.6 10.1 0.42 10.7 2.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) ICAM_N PF03921.14 RUS71215.1 - 0.16 11.7 1.4 1.7 8.4 0.1 2.3 1 1 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF4367 PF14285.6 RUS71215.1 - 1.9 9.0 8.4 5.6 7.4 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) Rootletin PF15035.6 RUS71215.1 - 2 8.4 11.9 12 5.8 1.0 2.7 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Myotub-related PF06602.14 RUS71216.1 - 0.034 13.1 0.3 12 4.7 0.0 2.9 1 1 2 3 3 3 0 Myotubularin-like phosphatase domain DUF4648 PF15505.6 RUS71216.1 - 0.75 10.7 5.2 30 5.6 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4648) DUF5545 PF17699.1 RUS71216.1 - 0.81 9.5 10.6 16 5.3 0.5 3.2 1 1 1 3 3 3 0 Family of unknown function (DUF5545) DUF4727 PF15856.5 RUS71216.1 - 1.9 8.0 5.6 13 5.2 0.6 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4727) DUF4744 PF15918.5 RUS71216.1 - 4.2 8.3 10.4 2.3e+03 -0.5 10.4 3.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) Acetyltransf_10 PF13673.7 RUS71218.1 - 6.8e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS71218.1 - 0.0003 21.0 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_2 PF12796.7 RUS71219.1 - 3.3e-105 344.8 48.1 2.4e-17 63.3 0.7 8.9 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 RUS71219.1 - 1.6e-88 287.6 42.1 3.2e-08 33.6 0.1 15.9 17 0 0 17 17 17 15 Ankyrin repeat Ank_3 PF13606.6 RUS71219.1 - 7.8e-76 240.9 22.9 1.6e-05 24.9 0.1 16.3 16 0 0 16 16 16 16 Ankyrin repeat Ank_5 PF13857.6 RUS71219.1 - 5.7e-74 243.2 54.1 1.7e-10 40.9 0.7 10.9 3 2 10 13 13 13 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS71219.1 - 2.7e-71 235.1 19.8 2.6e-09 37.4 0.0 14.1 5 2 10 16 16 16 12 Ankyrin repeats (many copies) BCS1_N PF08740.11 RUS71219.1 - 1.3e-06 28.5 0.0 3.6 7.5 0.0 5.4 2 1 2 5 5 5 2 BCS1 N terminal DUF249 PF03158.13 RUS71219.1 - 0.0023 17.7 0.1 1.9 8.2 0.1 4.4 2 2 2 4 4 4 1 Multigene family 530 protein CdAMP_rec PF06153.11 RUS71219.1 - 0.029 14.6 1.1 0.46 10.7 0.1 3.3 3 1 0 3 3 3 0 Cyclic-di-AMP receptor GST_N_5 PF18485.1 RUS71219.1 - 0.051 13.9 0.1 8.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain Phage_T7_Capsid PF05396.11 RUS71219.1 - 2.5 8.5 5.1 74 3.7 0.0 4.2 4 1 0 5 5 5 0 Phage T7 capsid assembly protein APG6 PF04111.12 RUS71220.1 - 4.8e-73 244.9 0.2 9.2e-73 244.0 0.2 1.5 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 RUS71220.1 - 2.9e-28 99.0 29.5 2.9e-28 99.0 29.5 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region BH3 PF15285.6 RUS71220.1 - 0.00032 20.4 0.2 0.00068 19.3 0.2 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting DUF3324 PF11797.8 RUS71220.1 - 0.12 12.3 2.5 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) Glutaminase PF04960.15 RUS71220.1 - 0.29 10.3 0.9 0.73 9.0 0.7 1.7 2 0 0 2 2 2 0 Glutaminase FapA PF03961.13 RUS71220.1 - 0.31 9.6 9.5 0.7 8.4 9.5 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A SpecificRecomb PF10136.9 RUS71220.1 - 0.36 9.1 3.4 0.49 8.7 3.4 1.1 1 0 0 1 1 1 0 Site-specific recombinase Exonuc_VII_L PF02601.15 RUS71220.1 - 0.79 9.2 3.9 1.4 8.5 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 RUS71220.1 - 5 6.4 8.8 7.9 5.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3280 PF11684.8 RUS71220.1 - 5.1 7.5 0.0 5.1 7.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2380) CENP-H PF05837.12 RUS71220.1 - 9.4 6.7 15.9 3.1 8.2 12.8 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ank_4 PF13637.6 RUS71222.1 - 6.6e-10 39.3 0.1 1.3e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS71222.1 - 3e-09 37.3 0.0 6.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS71222.1 - 5e-07 29.5 0.1 0.0016 18.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS71222.1 - 1.6e-06 28.3 0.1 0.022 15.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 RUS71222.1 - 1.2e-05 24.6 8.2 0.0017 17.9 2.6 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ank_5 PF13857.6 RUS71222.1 - 1.8e-05 24.9 0.1 4.9e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) End3 PF12761.7 RUS71223.1 - 0.22 11.7 7.6 0.5 10.5 7.6 1.6 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Glyco_transf_11 PF01531.16 RUS71224.1 - 1.1e-24 87.1 0.0 1.3e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Cadherin PF00028.17 RUS71225.1 - 1.6e-92 304.1 4.9 4e-22 78.5 0.0 5.1 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 RUS71225.1 - 4.7e-11 42.4 0.0 0.0098 15.7 0.0 4.4 4 0 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 RUS71225.1 - 1.4e-06 28.2 3.7 0.051 13.6 0.2 5.4 5 0 0 5 5 5 1 Cadherin-like RET_CLD1 PF17756.1 RUS71225.1 - 0.00063 20.0 0.0 9.1 6.6 0.0 4.0 4 1 0 4 4 4 2 RET Cadherin like domain 1 Luciferase_N PF05295.11 RUS71225.1 - 0.0035 17.3 0.0 0.054 13.5 0.0 2.3 2 0 0 2 2 2 1 Luciferase/LBP N-terminal domain Cadherin_4 PF17803.1 RUS71225.1 - 0.0062 17.1 26.1 1.1 9.9 1.2 5.5 4 1 1 5 5 5 2 Bacterial cadherin-like domain SusE PF14292.6 RUS71225.1 - 0.016 15.5 2.6 0.34 11.2 0.2 3.2 3 0 0 3 3 3 0 SusE outer membrane protein ZirS_C PF16583.5 RUS71225.1 - 0.02 14.5 1.4 1.6 8.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-regulated secreted antivirulence protein C-terminal domain Big_9 PF17963.1 RUS71225.1 - 2.9 8.7 23.5 0.44 11.3 1.2 4.7 4 1 0 4 4 4 0 Bacterial Ig domain EzrA PF06160.12 RUS71226.1 - 0.00012 20.4 38.2 0.00012 20.4 38.2 4.5 3 1 2 5 5 5 1 Septation ring formation regulator, EzrA MnmE_helical PF12631.7 RUS71227.1 - 1.5e-48 165.8 0.2 1.9e-48 165.3 0.2 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 RUS71227.1 - 8.5e-36 122.8 0.0 1.6e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 RUS71227.1 - 9.7e-21 74.0 0.0 1.9e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS71227.1 - 1.8e-07 30.8 0.2 5.5e-07 29.2 0.0 1.9 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS71227.1 - 9.5e-07 28.9 0.0 0.043 13.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 RUS71227.1 - 0.00052 20.0 0.1 0.0026 17.7 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 RUS71227.1 - 0.0027 17.8 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 RUS71227.1 - 0.003 18.0 0.0 0.0072 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 RUS71227.1 - 0.0051 16.4 0.1 0.25 10.9 0.1 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2420 PF10336.9 RUS71227.1 - 0.02 14.9 0.1 7.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) MCM PF00493.23 RUS71227.1 - 0.031 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 RUS71227.1 - 0.037 13.6 0.2 14 5.1 0.0 3.3 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RUS71227.1 - 0.037 13.7 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS71227.1 - 0.067 13.5 0.0 21 5.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 RUS71227.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Baculo_PEP_C PF04513.12 RUS71228.1 - 0.012 15.6 1.9 0.026 14.5 1.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.12 RUS71228.1 - 0.026 14.8 5.3 0.026 14.8 5.3 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Troponin PF00992.20 RUS71228.1 - 0.058 13.7 16.4 0.13 12.6 2.9 2.6 1 1 1 2 2 2 0 Troponin Spc7 PF08317.11 RUS71228.1 - 0.061 12.2 14.8 0.12 11.2 14.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein GD_AH_C PF04295.13 RUS71228.1 - 0.063 12.1 0.4 0.097 11.5 0.4 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus LMBR1 PF04791.16 RUS71228.1 - 0.13 11.1 4.0 0.2 10.5 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TssO PF17561.2 RUS71228.1 - 0.15 12.1 5.8 0.29 11.2 5.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO GrpE PF01025.19 RUS71228.1 - 6.6 6.4 14.9 2.6 7.7 7.3 2.6 1 1 1 2 2 2 0 GrpE Per1 PF04080.13 RUS71230.1 - 9.3e-90 300.8 20.1 1.2e-89 300.5 20.1 1.1 1 0 0 1 1 1 1 Per1-like family DUF2838 PF10998.8 RUS71230.1 - 0.0081 16.4 0.5 0.0081 16.4 0.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) UNC-93 PF05978.16 RUS71230.1 - 0.28 10.9 7.7 0.49 10.1 7.7 1.4 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 NMN_transporter PF04973.12 RUS71230.1 - 0.33 10.9 19.0 1.8 8.5 7.7 2.3 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter TPH PF13868.6 RUS71231.1 - 3.6e-14 52.0 121.7 3.6e-14 52.0 121.7 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ntox35 PF15534.6 RUS71231.1 - 1.1 9.8 6.2 0.31 11.5 1.5 2.6 2 0 0 2 2 2 0 Bacterial toxin 35 WD40 PF00400.32 RUS71232.1 - 4.8e-13 49.4 19.3 6e-05 23.7 0.2 8.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71232.1 - 1.3e-10 41.4 0.7 0.0021 18.3 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Spo7_2_N PF15407.6 RUS71233.1 - 0.04 13.6 1.2 1.2 8.9 0.5 2.9 1 1 1 2 2 2 0 Sporulation protein family 7 Pet191_N PF10203.9 RUS71233.1 - 0.41 11.0 2.9 12 6.3 0.8 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 VCPO_N PF17897.1 RUS71234.1 - 0.0075 16.1 13.1 4.7 7.0 0.1 3.9 1 1 3 4 4 4 4 Vanadium chloroperoxidase N-terminal domain DUF1720 PF08226.11 RUS71234.1 - 0.14 12.6 30.3 1.8e+04 -11.2 30.3 4.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) WD40 PF00400.32 RUS71235.1 - 2.8e-08 34.3 0.1 0.00079 20.2 0.0 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat Lectin_C PF00059.21 RUS71236.1 - 8.1e-12 45.8 0.1 9.1e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Lectin C-type domain DUF3094 PF11293.8 RUS71236.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DUF1794 PF08768.11 RUS71237.1 - 1.8e-18 66.9 0.0 3.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) FAR1 PF03101.15 RUS71237.1 - 0.00027 21.6 1.4 0.00027 21.6 1.4 3.4 3 0 0 3 3 3 1 FAR1 DNA-binding domain TPR_2 PF07719.17 RUS71238.1 - 8.6e-24 81.7 19.9 0.0024 17.9 0.0 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS71238.1 - 1.6e-23 82.7 10.6 3.5e-21 75.2 6.0 4.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RUS71238.1 - 2.2e-23 81.0 7.9 5.6e-05 22.8 0.0 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 RUS71238.1 - 4.6e-14 51.8 4.8 0.00018 21.3 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS71238.1 - 9.8e-14 51.4 17.1 1.1e-10 41.6 0.8 6.9 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS71238.1 - 1.2e-12 46.9 10.3 0.0014 18.5 0.2 5.9 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RUS71238.1 - 1.7e-12 46.5 6.1 0.0067 16.6 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS71238.1 - 1.3e-09 38.4 0.2 0.00039 20.9 0.0 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS71238.1 - 1.1e-07 32.1 5.3 5.5 8.1 0.1 7.8 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71238.1 - 2.6e-07 31.1 6.3 0.0097 16.5 0.1 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS71238.1 - 6e-07 29.0 0.1 0.00031 20.3 0.0 4.8 6 1 1 7 7 6 1 TPR repeat TPR_17 PF13431.6 RUS71238.1 - 1.1e-05 25.4 0.5 48 4.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 RUS71238.1 - 3.6e-05 23.8 1.8 0.00066 19.8 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS71238.1 - 0.00033 21.1 6.1 20 6.1 0.5 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RUS71238.1 - 0.0049 16.9 3.8 0.0097 15.9 1.9 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat DUF3808 PF10300.9 RUS71238.1 - 0.016 14.0 3.6 2.6 6.7 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPR_3 PF07720.12 RUS71238.1 - 0.017 15.1 12.1 6.3 6.9 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS71238.1 - 0.019 14.4 2.5 0.085 12.2 0.2 2.8 3 1 0 3 3 3 0 MalT-like TPR region Foie-gras_1 PF11817.8 RUS71238.1 - 0.066 12.8 0.3 0.21 11.2 0.3 1.8 1 0 0 1 1 1 0 Foie gras liver health family 1 Tudor_2 PF18104.1 RUS71238.1 - 0.12 12.0 0.0 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain MIT PF04212.18 RUS71238.1 - 0.23 11.5 1.5 30 4.8 0.1 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 RUS71238.1 - 2.2 8.4 6.6 38 4.5 0.3 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Patatin PF01734.22 RUS71240.1 - 1e-13 51.9 0.2 2.2e-13 50.9 0.2 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Carb_anhydrase PF00194.21 RUS71242.1 - 7.3e-55 186.2 0.0 8.3e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase EGF_CA PF07645.15 RUS71243.1 - 1.8e-25 88.9 120.0 1.8e-07 31.2 12.8 10.2 9 2 2 11 11 11 6 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS71243.1 - 2.4e-21 75.7 117.2 1.5e-08 34.7 12.4 10.0 8 2 2 10 10 10 6 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS71243.1 - 2.6e-19 68.8 83.1 2.7e-05 24.0 3.0 10.9 10 1 0 10 10 10 7 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS71243.1 - 2.8e-11 43.4 88.7 0.00035 20.7 11.4 9.3 10 0 0 10 10 10 6 EGF domain Sushi PF00084.20 RUS71243.1 - 2.4e-09 37.6 13.4 9.6e-07 29.3 2.0 7.0 5 1 2 7 7 7 2 Sushi repeat (SCR repeat) EGF PF00008.27 RUS71243.1 - 2.7e-09 37.1 93.9 0.00039 20.6 6.9 9.5 9 1 0 9 9 9 6 EGF-like domain Ephrin_rec_like PF07699.13 RUS71243.1 - 1.6e-08 34.1 16.8 2.2e-08 33.7 7.7 5.9 7 1 0 7 7 7 2 Putative ephrin-receptor like hEGF PF12661.7 RUS71243.1 - 0.0029 18.2 83.3 0.067 13.8 3.4 12.0 11 2 1 12 12 12 5 Human growth factor-like EGF zf-C2H2 PF00096.26 RUS71244.1 - 7.6e-08 32.4 47.5 0.048 14.1 1.9 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS71244.1 - 5.4e-07 29.8 0.9 5.4e-07 29.8 0.9 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS71244.1 - 0.00041 21.0 52.4 0.8 10.7 0.5 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS71244.1 - 0.63 10.1 20.6 0.5 10.4 0.1 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-SNAP50_C PF12251.8 RUS71244.1 - 2 8.1 12.8 4.5 6.9 0.5 3.5 2 1 1 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal zf-met PF12874.7 RUS71244.1 - 2.9 8.4 20.0 1.8 9.1 0.0 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RUS71244.1 - 3.2 7.4 12.7 6.8 6.4 0.1 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 RUS71244.1 - 7.9 6.9 13.1 47 4.4 0.4 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FXa_inhibition PF14670.6 RUS71245.1 - 9.7e-18 64.2 23.9 5.4e-11 42.6 9.7 2.6 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS71245.1 - 2.6e-09 36.8 10.7 8.7e-06 25.6 0.4 3.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS71245.1 - 1.3e-05 25.3 10.5 1.3e-05 25.3 10.5 3.1 3 1 0 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 RUS71245.1 - 0.00023 21.3 18.2 0.0048 17.1 3.8 2.9 2 0 0 2 2 2 2 EGF domain Plasmod_Pvs28 PF06247.11 RUS71245.1 - 0.15 12.4 17.9 0.76 10.1 0.1 3.7 2 1 2 4 4 4 0 Pvs28 EGF domain EGF PF00008.27 RUS71245.1 - 0.26 11.6 27.8 0.34 11.3 7.3 2.9 3 0 0 3 3 3 0 EGF-like domain DDE_Tnp_1_7 PF13843.6 RUS71247.1 - 3.2e-33 115.5 0.0 4.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 SAA PF00277.18 RUS71247.1 - 0.041 14.3 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Serum amyloid A protein Dicty_REP PF05086.12 RUS71249.1 - 0.071 11.1 0.7 0.08 10.9 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sina PF03145.16 RUS71251.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Seven in absentia protein family MbeD_MobD PF04899.12 RUS71252.1 - 0.023 14.8 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 MbeD/MobD like Astacin PF01400.24 RUS71254.1 - 5.6e-54 182.7 0.2 9.2e-54 182.0 0.2 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 RUS71254.1 - 3.7e-05 23.9 12.9 3.7e-05 23.9 12.9 2.9 2 0 0 2 2 2 1 Thrombospondin type 1 domain Peptidase_M10 PF00413.24 RUS71254.1 - 0.062 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin PAF-AH_p_II PF03403.13 RUS71255.1 - 7.7e-53 179.4 0.0 9.2e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 RUS71255.1 - 0.00074 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RUS71255.1 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 RUS71255.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 RUS71255.1 - 0.015 15.9 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 RUS71255.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 RUS71255.1 - 0.067 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 RUS71255.1 - 0.11 11.9 0.2 11 5.4 0.1 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Myosin_head PF00063.21 RUS71256.1 - 5.2e-11 41.5 0.0 5.2e-11 41.5 0.0 3.4 3 1 0 3 3 3 1 Myosin head (motor domain) AAA_22 PF13401.6 RUS71256.1 - 0.00022 21.5 0.0 0.00038 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS71256.1 - 0.0059 17.0 0.0 0.0069 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Myosin_head PF00063.21 RUS71257.1 - 5.6e-209 695.7 0.4 8.1e-209 695.2 0.4 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RUS71257.1 - 3.4e-42 144.2 0.9 3.4e-42 144.2 0.9 2.0 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 RUS71257.1 - 3.3e-05 23.3 15.9 1.3 9.1 0.0 5.5 5 0 0 5 5 5 4 IQ calmodulin-binding motif NCBP3 PF10309.9 RUS71257.1 - 0.046 13.6 0.3 0.095 12.6 0.3 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 FA_hydroxylase PF04116.13 RUS71260.1 - 2.8e-25 89.2 13.4 2.8e-25 89.2 13.4 2.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF3792 PF12670.7 RUS71260.1 - 0.0082 16.3 0.5 0.0082 16.3 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3792) Vps16_N PF04841.13 RUS71261.1 - 3.4e-100 335.7 0.4 1.9e-53 181.7 0.0 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 RUS71261.1 - 1.4e-90 303.6 3.1 2e-90 303.1 3.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Presenilin PF01080.17 RUS71262.1 - 3.3 6.4 3.7 4.1 6.1 3.7 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 RUS71263.1 - 0.83 9.2 11.5 1.1 8.7 11.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 RUS71263.1 - 3.1 6.9 10.2 4.2 6.5 10.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SKG6 PF08693.10 RUS71263.1 - 4.5 6.8 6.1 8.7 5.8 6.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Neur_chan_memb PF02932.16 RUS71263.1 - 5.5 7.0 6.9 8.3 6.4 6.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 RUS71265.1 - 0.11 10.7 33.4 0.14 10.3 33.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS71265.1 - 1.1 8.6 40.7 1.5 8.2 40.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2475 PF10629.9 RUS71266.1 - 2.5e-08 34.0 7.1 6.3e-06 26.3 0.3 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) DUF2475 PF10629.9 RUS71267.1 - 3.6e-10 39.9 0.8 5.7e-10 39.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) Ank_2 PF12796.7 RUS71268.1 - 5.9e-20 71.6 0.9 5.2e-09 36.6 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS71268.1 - 1.7e-17 63.5 0.5 2.7e-10 40.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS71268.1 - 7.7e-15 53.5 2.5 6.8e-06 26.1 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RUS71268.1 - 1.4e-14 53.8 0.7 0.00032 21.0 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RUS71268.1 - 6.8e-12 45.4 0.3 2.3e-06 27.7 0.1 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 RUS71268.1 - 8.5e-11 41.6 21.8 1.5e-10 40.7 21.8 1.4 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RUS71268.1 - 1.4e-06 27.2 7.7 1.4e-06 27.2 7.7 2.0 2 1 1 3 3 3 1 Polycystin cation channel DUF2157 PF09925.9 RUS71268.1 - 0.57 10.0 5.7 0.48 10.2 2.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) BTB PF00651.31 RUS71269.1 - 9.1e-25 87.0 0.0 7.6e-19 68.0 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 RUS71269.1 - 9.9e-05 22.4 0.5 10 6.3 0.0 4.3 4 0 0 4 4 4 3 BTB And C-terminal Kelch LRR_8 PF13855.6 RUS71270.1 - 4.5e-79 260.2 46.3 2.7e-15 55.9 1.1 8.2 4 2 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RUS71270.1 - 1.3e-42 143.1 39.3 3.1e-07 30.6 0.2 9.1 6 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS71270.1 - 3.7e-28 98.1 0.3 3e-11 43.4 2.2 4.4 2 2 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS71270.1 - 2.3e-20 70.0 37.0 0.045 14.3 0.0 15.4 16 0 0 16 16 16 4 Leucine Rich Repeat LRR_9 PF14580.6 RUS71270.1 - 6.8e-13 48.5 15.0 0.0052 16.3 2.4 4.5 2 2 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 RUS71270.1 - 1.9e-06 27.4 56.2 1.1 9.5 0.0 14.1 16 1 0 16 16 16 6 Leucine Rich repeat LRR_2 PF07723.13 RUS71270.1 - 3.1 8.6 13.2 39 5.1 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat BTG PF07742.12 RUS71272.1 - 5e-34 116.6 0.0 8.3e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 BTG family SelP_N PF04592.14 RUS71272.1 - 5 6.4 22.8 10 5.4 22.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GpcrRhopsn4 PF10192.9 RUS71273.1 - 1.4e-60 204.9 29.0 1.8e-60 204.5 29.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RUS71273.1 - 1.3 8.2 34.4 0.34 10.1 30.5 1.9 2 1 0 2 2 2 0 Lung seven transmembrane receptor DCX PF03607.17 RUS71274.1 - 0.0083 16.2 0.0 9.8 6.4 0.0 3.5 1 1 1 2 2 2 2 Doublecortin Perm-CXXC PF15629.6 RUS71274.1 - 0.43 10.9 11.0 71 3.8 0.6 5.1 1 1 4 7 7 7 0 Permuted single zf-CXXC unit Transposase_1 PF01359.18 RUS71275.1 - 1.2e-18 66.7 0.0 2.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS71275.1 - 9.5e-08 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS71275.1 - 0.00037 20.7 0.2 0.00074 19.7 0.2 1.5 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS71275.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS71275.1 - 0.05 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 RUS71275.1 - 0.09 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PCI PF01399.27 RUS71275.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 PCI domain HTH_Tnp_ISL3 PF13542.6 RUS71275.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Laminin_EGF PF00053.24 RUS71276.1 - 0.0093 16.1 46.3 0.11 12.6 10.7 3.7 1 1 2 3 3 3 2 Laminin EGF domain FSA_C PF10479.9 RUS71277.1 - 1.5e-163 545.6 7.1 5.8e-132 441.2 0.6 3.5 2 1 1 3 3 3 2 Fragile site-associated protein C-terminus Inh PF02974.14 RUS71277.1 - 0.22 11.6 2.8 0.95 9.6 0.2 2.6 2 0 0 2 2 2 0 Protease inhibitor Inh VIT1 PF01988.19 RUS71278.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 VIT family Ndc1_Nup PF09531.10 RUS71278.1 - 0.00076 18.3 5.6 0.0008 18.2 5.6 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup AAA_11 PF13086.6 RUS71278.1 - 0.019 14.8 26.6 0.03 14.1 26.6 1.3 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 RUS71278.1 - 0.12 11.2 11.8 0.17 10.6 11.8 1.3 1 0 0 1 1 1 0 Fungal protein kinase NPR3 PF03666.13 RUS71278.1 - 0.41 9.4 43.5 0.62 8.8 43.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Velvet PF11754.8 RUS71278.1 - 1.2 9.0 13.2 1.7 8.6 13.2 1.2 1 0 0 1 1 1 0 Velvet factor PepSY_TM_like_2 PF16357.5 RUS71278.1 - 1.5 8.8 7.6 2.4 8.1 7.5 1.5 1 1 0 1 1 1 0 Putative PepSY_TM-like SLC12 PF03522.15 RUS71278.1 - 3.5 6.5 40.5 4.5 6.2 40.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF262 PF03235.14 RUS71278.1 - 4 7.6 20.9 5.3 7.1 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 SWI-SNF_Ssr4 PF08549.10 RUS71278.1 - 5.8 5.4 18.2 7 5.1 18.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF4776 PF16003.5 RUS71278.1 - 6.4 5.7 50.4 7.5 5.4 50.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) ALMT PF11744.8 RUS71278.1 - 7.5 5.3 29.7 15 4.3 29.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MAM PF00629.23 RUS71279.1 - 9e-14 51.7 0.8 3.1e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 RUS71280.1 - 1.1e-19 70.9 0.2 2.4e-19 69.8 0.2 1.5 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu SDA1 PF05285.12 RUS71281.1 - 0.036 13.5 27.3 0.078 12.4 27.3 1.4 1 0 0 1 1 1 0 SDA1 Tetraspanin PF00335.20 RUS71281.1 - 0.038 13.7 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family FAM75 PF14650.6 RUS71281.1 - 0.52 9.8 10.1 0.76 9.3 10.1 1.1 1 0 0 1 1 1 0 FAM75 family CDC45 PF02724.14 RUS71281.1 - 0.54 8.5 17.2 1.1 7.5 17.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS71281.1 - 0.83 7.8 33.5 1.3 7.1 33.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2207 PF09972.9 RUS71282.1 - 0.00034 19.5 0.0 0.00049 19.0 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 RUS71282.1 - 0.008 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 RUS71282.1 - 0.024 15.5 0.0 0.056 14.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 RUS71282.1 - 0.081 12.7 0.8 0.15 11.8 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Amnionless PF14828.6 RUS71282.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless FAM176 PF14851.6 RUS71282.1 - 0.19 11.4 0.2 1 9.0 0.0 2.1 1 1 1 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 RUS71284.1 - 0.0019 16.4 35.7 0.0044 15.2 35.1 1.7 2 0 0 2 2 2 1 DNA polymerase phi Nop14 PF04147.12 RUS71284.1 - 0.0022 16.3 18.6 0.0027 16.0 18.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS71284.1 - 0.0036 15.7 15.3 0.0042 15.5 15.3 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 RUS71284.1 - 0.013 15.6 18.0 0.017 15.2 18.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 RUS71284.1 - 0.023 14.2 19.4 0.03 13.7 19.4 1.2 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 RUS71284.1 - 0.056 13.2 9.9 0.088 12.6 9.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop53 PF07767.11 RUS71284.1 - 0.21 10.9 5.0 0.3 10.4 5.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mpp10 PF04006.12 RUS71284.1 - 0.24 9.8 18.3 0.28 9.6 18.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RUS71284.1 - 0.56 9.6 16.8 0.72 9.2 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 RUS71284.1 - 0.8 8.6 11.7 1 8.2 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 RUS71284.1 - 1.6 7.9 18.3 2.4 7.4 18.3 1.3 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 RUS71284.1 - 2.1 7.9 19.5 2.9 7.4 19.5 1.3 1 0 0 1 1 1 0 PPP4R2 IFT57 PF10498.9 RUS71284.1 - 2.6 6.9 7.0 3.2 6.6 7.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SGT1 PF07093.11 RUS71284.1 - 4.1 5.7 15.6 22 3.3 15.3 2.0 2 0 0 2 2 2 0 SGT1 protein CNDH2_C PF16858.5 RUS71284.1 - 8.3 6.2 12.1 11 5.8 12.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Herpes_pp85 PF04637.12 RUS71285.1 - 0.62 8.4 3.5 1.2 7.4 3.5 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) T-box PF00907.22 RUS71286.1 - 6.1e-80 267.8 0.0 7.4e-80 267.5 0.0 1.1 1 0 0 1 1 1 1 T-box TFIIA PF03153.13 RUS71286.1 - 0.012 15.6 27.0 0.014 15.4 27.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 RUS71286.1 - 0.021 14.7 7.3 0.029 14.2 7.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 RUS71286.1 - 0.34 9.0 49.9 0.44 8.6 49.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 RUS71286.1 - 0.39 10.1 33.5 0.57 9.6 33.5 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS71286.1 - 0.4 10.0 23.6 0.55 9.6 23.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 RUS71286.1 - 0.89 8.3 6.9 0.99 8.1 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop25 PF09805.9 RUS71286.1 - 1.4 9.3 15.0 2.8 8.4 15.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.12 RUS71286.1 - 10 4.2 37.1 13 3.8 37.1 1.1 1 0 0 1 1 1 0 Nop14-like family zf_C2H2_10 PF18414.1 RUS71287.1 - 0.0068 15.9 32.9 14 5.3 0.3 7.1 7 0 0 7 7 7 7 C2H2 type zinc-finger DUF3931 PF13082.6 RUS71287.1 - 0.037 14.2 22.5 2.2 8.5 0.8 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF3931) CHORD PF04968.12 RUS71287.1 - 0.33 11.7 12.4 1.5e+02 3.2 0.1 6.0 1 1 6 7 7 7 0 CHORD THEG4 PF15834.5 RUS71287.1 - 2.7 7.9 10.6 32 4.4 0.5 3.1 1 1 4 5 5 5 0 Testis highly expressed protein 4 ketoacyl-synt PF00109.26 RUS71288.1 - 8e-51 173.1 0.0 1.1e-50 172.6 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS71288.1 - 4.7e-38 129.8 0.0 1.6e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 RUS71288.1 - 2.9e-31 108.2 0.0 5.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 RUS71288.1 - 0.01 15.7 0.2 0.024 14.5 0.2 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III VERL PF11386.8 RUS71289.1 - 0.00021 21.4 3.3 0.79 9.9 0.3 3.8 1 1 2 3 3 3 3 Vitelline envelope receptor for lysin DUF2788 PF10981.8 RUS71289.1 - 0.03 14.3 5.3 74 3.5 0.0 5.3 6 1 1 7 7 7 0 Protein of unknown function (DUF2788) FAM101 PF15068.6 RUS71289.1 - 0.043 13.8 3.7 0.23 11.4 2.2 1.9 1 1 1 2 2 2 0 FAM101 family EndIII_4Fe-2S PF10576.9 RUS71289.1 - 0.062 13.7 0.0 2.9e+02 2.0 0.0 4.5 5 0 0 5 5 5 0 Iron-sulfur binding domain of endonuclease III hEGF PF12661.7 RUS71289.1 - 0.096 13.3 10.5 25 5.7 0.1 6.1 7 0 0 7 7 7 0 Human growth factor-like EGF T2SSppdC PF12528.8 RUS71289.1 - 1.3 9.8 15.6 80 4.1 0.1 5.5 1 1 5 6 6 6 0 Type II secretion prepilin peptidase dependent protein C PhyH PF05721.13 RUS71290.1 - 0.0028 18.0 0.2 0.013 15.7 0.2 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_25 PF13649.6 RUS71292.1 - 3.3e-14 53.3 0.0 1.7e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS71292.1 - 2.8e-12 47.1 0.0 1e-11 45.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS71292.1 - 4.4e-10 39.6 0.0 7.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS71292.1 - 9.4e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 RUS71292.1 - 0.00017 21.3 0.0 0.0005 19.8 0.0 1.7 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 RUS71292.1 - 0.00022 21.9 0.0 0.0013 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 RUS71292.1 - 0.00092 18.3 0.0 0.001 18.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 RUS71292.1 - 0.003 17.1 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 RUS71292.1 - 0.004 17.2 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS71292.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 RUS71292.1 - 0.02 15.0 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase HLH PF00010.26 RUS71293.1 - 2.9e-12 46.4 0.7 7.5e-12 45.0 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_fiss_reg PF05308.11 RUS71293.1 - 3.2 7.8 10.1 4.9 7.2 2.5 2.4 2 1 0 2 2 2 0 Mitochondrial fission regulator CDC45 PF02724.14 RUS71293.1 - 8.7 4.5 9.4 10 4.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FeS_assembly_P PF01883.19 RUS71295.1 - 8.9e-17 61.0 0.5 1.2e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Carb_anhydrase PF00194.21 RUS71296.1 - 1.4e-73 247.5 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pro_isomerase PF00160.21 RUS71297.1 - 0.059 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7tm_2 PF00002.24 RUS71298.1 - 0.011 15.1 16.0 0.02 14.2 16.0 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) CTP_transf_like PF01467.26 RUS71299.1 - 6.6e-10 39.3 0.3 6.9e-09 36.0 0.3 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 RUS71299.1 - 0.0042 17.0 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 FAD synthetase Na_Pi_cotrans PF02690.15 RUS71300.1 - 2.1e-36 125.0 28.8 1.2e-22 80.5 6.1 2.9 2 1 0 3 3 3 2 Na+/Pi-cotransporter Iron_permease PF04120.12 RUS71300.1 - 0.13 12.1 0.6 0.36 10.6 0.6 1.7 1 0 0 1 1 1 0 Low affinity iron permease DUF4714 PF15833.5 RUS71300.1 - 0.66 9.9 2.6 24 4.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) Na_Pi_cotrans PF02690.15 RUS71301.1 - 1.5e-20 73.7 9.3 1.5e-20 73.7 9.3 1.0 1 0 0 1 1 1 1 Na+/Pi-cotransporter ADH_N PF08240.12 RUS71302.1 - 8.2e-27 93.2 0.4 2.4e-26 91.8 0.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS71302.1 - 1e-18 67.5 0.0 2.6e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RUS71302.1 - 0.00056 19.4 0.4 0.001 18.6 0.4 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus PALP PF00291.25 RUS71302.1 - 0.055 12.9 0.2 0.099 12.0 0.2 1.4 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 RUS71302.1 - 0.067 12.5 0.5 0.16 11.3 0.2 1.7 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 RUS71303.1 - 6.2e-29 100.1 1.1 1.5e-28 98.8 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS71303.1 - 1.1e-22 80.4 0.0 4.1e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RUS71303.1 - 5.1e-09 35.9 0.1 8.4e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RUS71303.1 - 0.0077 17.3 0.0 0.013 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RUS71303.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 5TM-5TMR_LYT PF07694.12 RUS71303.1 - 1.9 8.0 16.1 3.8 7.0 11.3 2.2 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Aldedh PF00171.22 RUS71304.1 - 6.5e-178 592.0 0.2 7.4e-178 591.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5055 PF16478.5 RUS71305.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) AAA PF00004.29 RUS71306.1 - 1.4e-09 38.5 0.0 2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ANF_receptor PF01094.28 RUS71307.1 - 4.3e-13 49.1 0.0 4.9e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS71307.1 - 0.018 14.7 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Periplasmic binding protein Branch PF02485.21 RUS71309.1 - 1.3e-18 67.5 0.1 1.3e-18 67.5 0.1 1.8 2 0 0 2 2 2 1 Core-2/I-Branching enzyme YrhK PF14145.6 RUS71310.1 - 0.92 9.4 5.3 2.3 8.1 5.3 1.6 1 1 0 1 1 1 0 YrhK-like protein InvH PF04741.12 RUS71313.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 InvH outer membrane lipoprotein CAP PF00188.26 RUS71314.1 - 1.2e-20 74.6 0.7 1.8e-20 74.1 0.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 RUS71315.1 - 1e-16 61.9 0.3 1e-16 61.9 0.3 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family 4HBT_2 PF13279.6 RUS71317.1 - 0.0079 16.7 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase-like superfamily Penaeidin PF05927.11 RUS71317.1 - 0.058 14.1 0.3 2.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Penaeidin UPF0139 PF03669.13 RUS71320.1 - 2.3e-49 165.2 0.3 2.6e-49 165.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) protein_MS5 PF04776.12 RUS71320.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein MS5 TPR_12 PF13424.6 RUS71321.1 - 8.9e-10 38.7 4.1 0.00022 21.4 0.1 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat AAA_16 PF13191.6 RUS71321.1 - 1.8e-06 28.5 0.1 1.9e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 RUS71321.1 - 6.3e-06 26.2 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 RUS71321.1 - 2.2e-05 24.2 6.9 0.32 10.9 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS71321.1 - 0.019 15.5 2.6 0.041 14.4 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 RUS71321.1 - 0.03 14.6 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RUS71321.1 - 0.031 14.3 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPR_7 PF13176.6 RUS71321.1 - 0.1 12.7 0.6 15 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DHR-2 PF06920.13 RUS71322.1 - 4.1e-204 679.1 10.1 5.9e-204 678.6 10.1 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 RUS71322.1 - 5.6e-49 166.6 0.2 1.2e-48 165.5 0.2 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 RUS71322.1 - 1.2e-28 99.8 2.6 5.6e-28 97.6 2.6 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 RUS71322.1 - 0.001 18.1 3.5 0.0012 17.9 0.0 2.7 4 0 0 4 4 4 1 DOCK N-terminus Na_Ca_ex PF01699.24 RUS71324.1 - 1.7e-30 106.0 14.9 1.7e-30 106.0 14.9 1.7 2 0 0 2 2 2 1 Sodium/calcium exchanger protein DUF2527 PF10736.9 RUS71324.1 - 0.033 14.0 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) zf-met2 PF12907.7 RUS71324.1 - 0.066 13.4 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding FIST_C PF10442.9 RUS71326.1 - 2e-05 24.6 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FIST C domain F-box PF00646.33 RUS71326.1 - 0.005 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS71326.1 - 0.013 15.4 0.4 0.025 14.5 0.4 1.4 1 0 0 1 1 1 0 F-box-like DEP PF00610.21 RUS71328.1 - 1.5e-05 24.9 0.0 5.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pyridoxal_deC PF00282.19 RUS71329.1 - 1.4e-123 412.3 0.0 1.8e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RUS71329.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V ORC4_C PF14629.6 RUS71330.1 - 3.7e-37 127.8 0.0 9.7e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 RUS71330.1 - 9.9e-15 55.3 0.2 2.5e-14 54.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RUS71330.1 - 2.3e-10 41.0 0.0 4.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS71330.1 - 1.6e-08 34.9 0.1 3.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RUS71330.1 - 1.9e-06 27.3 0.0 3.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 RUS71330.1 - 0.00035 20.6 0.3 0.00078 19.4 0.3 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 RUS71330.1 - 0.00059 19.8 1.6 0.0023 17.8 1.6 2.1 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 RUS71330.1 - 0.002 18.2 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.6 RUS71330.1 - 0.0024 16.8 0.6 0.004 16.0 0.6 1.2 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.27 RUS71330.1 - 0.0031 18.0 0.0 0.0071 16.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 RUS71330.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 RUS71330.1 - 0.0046 16.4 0.2 0.013 14.9 0.2 1.7 1 1 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 RUS71330.1 - 0.0057 16.7 0.1 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RUS71330.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 RUS71330.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DAP3 PF10236.9 RUS71330.1 - 0.042 13.0 0.1 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 RUS71330.1 - 0.068 12.4 0.1 2.7 7.2 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 RUS71330.1 - 0.084 12.8 0.1 0.51 10.2 0.1 2.1 1 1 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 RUS71330.1 - 0.09 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 RUS71330.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RUS71330.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 RUS71330.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tim44 PF04280.15 RUS71333.1 - 2.9e-12 46.9 0.1 3.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 RUS71333.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 MBA1-like protein Serpin PF00079.20 RUS71334.1 - 1.3e-120 403.1 0.2 1.5e-120 402.9 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WAP PF00095.21 RUS71336.1 - 1.1e-09 38.5 19.8 1.1e-09 38.5 19.8 2.0 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Troponin-I_N PF11636.8 RUS71337.1 - 0.13 12.3 0.6 0.41 10.6 0.6 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF5305 PF17231.2 RUS71338.1 - 0.038 13.4 0.5 0.064 12.7 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Galactosyl_T PF01762.21 RUS71339.1 - 1.3e-43 149.1 4.3 1.5e-40 139.2 0.3 3.3 2 1 1 3 3 3 2 Galactosyltransferase Presenilin PF01080.17 RUS71339.1 - 0.015 14.1 5.6 0.03 13.1 5.6 1.6 1 0 0 1 1 1 0 Presenilin Apolipoprotein PF01442.18 RUS71339.1 - 0.063 13.1 14.0 39 4.1 14.0 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dsh_C PF12316.8 RUS71339.1 - 0.58 10.5 24.6 1.2 9.5 24.6 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4508 PF14969.6 RUS71339.1 - 0.84 9.9 5.6 1.9 8.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) YtxH PF12732.7 RUS71339.1 - 2.1 9.0 12.7 1.3e+04 -3.2 12.7 4.0 1 1 0 1 1 1 0 YtxH-like protein Lectin_C PF00059.21 RUS71340.1 - 6.1e-10 39.8 0.1 1.2e-09 38.9 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain ATP-synt_S1 PF05827.12 RUS71340.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DNA_pol_phi PF04931.13 RUS71341.1 - 9e-07 27.4 28.0 9e-07 27.4 28.0 2.1 2 0 0 2 2 2 2 DNA polymerase phi DUF913 PF06025.12 RUS71341.1 - 0.017 14.1 0.7 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 RUS71341.1 - 0.2 11.5 4.5 0.14 11.9 0.6 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Vfa1 PF08432.10 RUS71341.1 - 3.6 7.9 12.6 11 6.3 7.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nop25 PF09805.9 RUS71341.1 - 5.8 7.4 19.1 1.4 9.4 12.1 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.12 RUS71341.1 - 8.2 4.5 46.2 2.6 6.2 32.2 2.0 2 0 0 2 2 2 0 Nop14-like family RRM_1 PF00076.22 RUS71343.1 - 4.8e-36 122.4 1.0 1.6e-17 63.0 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS71343.1 - 1.9e-13 50.3 0.1 1.6e-05 24.9 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 RUS71343.1 - 0.00045 20.2 0.1 0.0055 16.7 0.0 2.2 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 RUS71343.1 - 0.009 16.0 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RVT_2 PF07727.14 RUS71344.1 - 3.7e-75 252.7 0.5 5.3e-75 252.2 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF432 PF04254.13 RUS71344.1 - 0.048 13.8 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF432) 7TM_GPCR_Srx PF10328.9 RUS71345.1 - 1.3e-08 34.8 20.3 1.9e-08 34.3 20.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS71345.1 - 4.4e-05 23.0 13.2 9e-05 21.9 13.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 RUS71345.1 - 0.043 13.5 19.2 0.41 10.3 19.2 2.2 1 1 0 1 1 1 0 Srg family chemoreceptor DUF4079 PF13301.6 RUS71345.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2721 PF11026.8 RUS71345.1 - 3.9 7.4 7.8 1.4 8.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Calpain_III PF01067.22 RUS71346.1 - 1.3e-15 57.9 0.0 3.9e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 Calpain large subunit, domain III RVT_1 PF00078.27 RUS71346.1 - 6.8e-15 55.2 0.2 1.2e-14 54.3 0.2 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pecanex_C PF05041.15 RUS71347.1 - 1.6e-117 391.0 0.0 2.5e-117 390.4 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF3678 PF12435.8 RUS71347.1 - 0.023 14.1 0.0 0.077 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) PP2C PF00481.21 RUS71348.1 - 1.3e-81 274.1 0.0 1.5e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 RUS71348.1 - 6.5e-27 93.8 0.1 1.8e-26 92.4 0.1 1.8 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 RUS71348.1 - 0.0095 15.6 0.0 0.058 13.0 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C MSG PF02349.15 RUS71348.1 - 0.098 12.9 1.4 0.19 11.9 1.4 1.4 1 0 0 1 1 1 0 Major surface glycoprotein Exo_endo_phos PF03372.23 RUS71349.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FMP23 PF17315.2 RUS71349.1 - 0.034 14.3 0.2 0.06 13.5 0.2 1.4 1 0 0 1 1 1 0 Found in mitochondrial proteome Exo_endo_phos_2 PF14529.6 RUS71349.1 - 0.045 13.6 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Gal-3-0_sulfotr PF06990.11 RUS71350.1 - 2.3e-46 158.5 5.4 2.1e-45 155.3 5.4 1.9 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase RT_RNaseH_2 PF17919.1 RUS71351.1 - 4e-11 42.8 0.0 7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS71351.1 - 0.0019 18.5 0.0 0.027 14.7 0.0 2.3 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase CAP PF00188.26 RUS71352.1 - 1.6e-09 38.7 0.4 2.2e-09 38.2 0.4 1.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Trypsin PF00089.26 RUS71354.1 - 3.9e-51 174.0 0.1 4.6e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RUS71354.1 - 0.00078 19.8 0.3 0.0017 18.7 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 RUS71354.1 - 0.0039 18.1 0.0 0.0077 17.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1256 PF06866.11 RUS71354.1 - 0.03 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) SIR2 PF02146.17 RUS71355.1 - 5.5e-36 124.1 0.0 7.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Med27 PF11571.8 RUS71355.1 - 0.031 14.6 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 27 MTHFR_C PF12225.8 RUS71355.1 - 0.046 13.4 0.6 0.086 12.5 0.6 1.4 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf-ribbon_3 PF13248.6 RUS71355.1 - 1.4 8.4 4.0 0.59 9.6 1.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain PP2C PF00481.21 RUS71356.1 - 1e-33 117.1 0.0 4.6e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C 7tm_1 PF00001.21 RUS71358.1 - 4.6e-34 117.9 23.6 4.6e-33 114.7 23.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.9 RUS71358.1 - 7.7 6.9 12.2 5.1 7.4 3.6 3.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain THAP PF05485.12 RUS71359.1 - 1.3e-10 42.1 0.8 1.8e-10 41.6 0.8 1.4 1 0 0 1 1 1 1 THAP domain BID PF06393.11 RUS71361.1 - 0.11 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) Fibrillarin PF01269.17 RUS71362.1 - 3.8e-37 127.6 0.1 4.2e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin RRN3 PF05327.11 RUS71363.1 - 1.4e-17 63.5 0.0 1.4e-17 63.5 0.0 1.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 N_Asn_amidohyd PF14736.6 RUS71364.1 - 5.7e-94 314.3 0.0 6.8e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Lig_chan PF00060.26 RUS71365.1 - 3.6e-16 59.3 0.0 5.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS71365.1 - 1.3e-12 47.7 0.2 1.7e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 RUS71366.1 - 5.3e-27 94.3 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RUS71366.1 - 6.3e-13 48.6 0.0 1.2e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RUS71366.1 - 2.1e-11 43.7 0.0 4.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 GOLGA2L5 PF15070.6 RUS71367.1 - 0.049 12.3 29.7 0.04 12.6 10.6 2.2 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 MAD PF05557.13 RUS71367.1 - 0.066 11.6 36.2 0.079 11.3 36.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CEP63 PF17045.5 RUS71367.1 - 0.23 11.3 36.4 0.51 10.2 36.4 1.6 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Fez1 PF06818.15 RUS71367.1 - 0.74 10.2 33.6 16 5.9 33.6 2.0 1 1 0 1 1 1 0 Fez1 ERM PF00769.19 RUS71367.1 - 2 8.2 40.0 15 5.3 40.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CNH PF00780.22 RUS71368.1 - 2.5e-36 125.7 0.0 3.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH PF00169.29 RUS71368.1 - 7.4e-09 36.1 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 RUS71368.1 - 2.1e-08 33.9 3.3 5.1e-08 32.7 3.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RUS71368.1 - 0.17 12.2 1.8 0.51 10.7 1.8 1.9 1 0 0 1 1 1 0 C1 domain MBR1 PF17058.5 RUS71368.1 - 2.8 8.2 7.7 7 6.9 7.7 1.6 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 LRR_9 PF14580.6 RUS71369.1 - 8.7e-10 38.4 2.9 1.8e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RUS71369.1 - 1.9e-08 33.9 17.5 3.2e-05 23.6 4.1 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RUS71369.1 - 5e-08 33.1 17.0 0.0083 16.5 0.6 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) FNIP PF05725.12 RUS71369.1 - 0.0058 16.8 0.3 0.017 15.2 0.2 1.9 2 0 0 2 2 2 1 FNIP Repeat Bac_luciferase PF00296.20 RUS71369.1 - 0.07 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase SR-25 PF10500.9 RUS71370.1 - 4.2e-36 124.7 58.2 4.2e-36 124.7 58.2 2.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein LAP1C PF05609.12 RUS71370.1 - 0.83 8.7 27.9 1.4 7.9 27.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 RUS71370.1 - 2.8 6.3 28.6 2.9 6.3 28.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hamartin PF04388.12 RUS71370.1 - 5.4 5.5 22.7 6.2 5.4 22.7 1.1 1 0 0 1 1 1 0 Hamartin protein Retinal PF15449.6 RUS71370.1 - 6.3 4.4 40.3 7.4 4.2 40.3 1.0 1 0 0 1 1 1 0 Retinal protein ubiquitin PF00240.23 RUS71372.1 - 9.9e-12 44.4 0.4 9.9e-05 22.0 0.1 3.7 3 1 0 3 3 3 3 Ubiquitin family Ank_2 PF12796.7 RUS71372.1 - 9.5e-06 26.1 0.1 0.018 15.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Rad60-SLD PF11976.8 RUS71372.1 - 0.003 17.3 1.6 0.06 13.2 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 RUS71372.1 - 0.0032 18.1 0.0 53 4.6 0.0 3.5 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD FeoA PF04023.14 RUS71372.1 - 0.01 16.1 0.0 7.6 6.9 0.0 3.5 3 0 0 3 3 3 1 FeoA domain Ank_4 PF13637.6 RUS71372.1 - 0.075 13.6 0.2 22 5.8 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Guanylate_cyc_2 PF09778.9 RUS71373.1 - 3.5e-68 229.1 0.1 4.1e-68 228.9 0.1 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 RUS71373.1 - 2e-08 34.9 0.0 1.7e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 RUS71373.1 - 9.1e-05 22.3 0.2 0.032 14.0 0.1 3.2 2 2 1 3 3 3 1 Peptidase C39 family Peptidase_C70 PF12385.8 RUS71373.1 - 0.0028 17.6 0.1 0.15 12.0 0.0 2.5 1 1 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 RUS71373.1 - 0.004 16.6 0.1 3.2 7.2 0.0 3.0 3 0 0 3 3 3 2 Peptidase_C39 like family DERM PF14704.6 RUS71374.1 - 2.2e-41 141.8 6.9 2.6e-41 141.6 6.9 1.0 1 0 0 1 1 1 1 Dermatopontin OSK PF17182.4 RUS71374.1 - 0.031 13.5 0.1 0.04 13.1 0.1 1.1 1 0 0 1 1 1 0 OSK domain DERM PF14704.6 RUS71375.1 - 9.2e-40 136.6 4.4 1.1e-39 136.3 4.4 1.0 1 0 0 1 1 1 1 Dermatopontin PMT PF02366.18 RUS71376.1 - 4.4e-69 232.8 19.7 4.4e-69 232.8 19.7 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 RUS71376.1 - 6.9e-26 91.2 3.1 1e-25 90.7 3.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_4TMC PF16192.5 RUS71376.1 - 4.4e-16 59.1 0.2 4.4e-16 59.1 0.2 2.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase DUF1240 PF06836.12 RUS71376.1 - 0.2 12.2 2.9 4.9 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) REV PF00424.18 RUS71377.1 - 0.16 12.0 1.9 3.8 7.6 0.3 2.1 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) RNase_H PF00075.24 RUS71380.1 - 3e-18 66.4 0.5 1.4e-17 64.2 0.5 2.0 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS71380.1 - 1.8e-05 24.5 0.3 7.1e-05 22.6 0.1 2.1 1 1 1 2 2 2 1 Reverse transcriptase-like YmgB PF10798.8 RUS71380.1 - 0.098 12.5 0.1 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR BRAP2 PF07576.12 RUS71381.1 - 9.9e-31 105.9 0.0 1.8e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 RUS71381.1 - 3e-20 72.3 5.7 3e-20 72.3 5.7 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 RUS71381.1 - 4.9e-09 36.4 7.2 4.9e-09 36.4 7.2 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS71381.1 - 3.1e-07 30.1 6.4 8.5e-07 28.7 6.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS71381.1 - 5.1e-06 26.7 5.5 5.1e-06 26.7 5.5 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RUS71381.1 - 8.9e-06 25.4 4.7 3.5e-05 23.4 4.7 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RUS71381.1 - 1.1e-05 25.2 6.4 4.2e-05 23.3 6.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS71381.1 - 0.00042 20.3 5.4 0.0009 19.2 4.0 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS71381.1 - 0.0012 18.8 4.8 0.0012 18.8 4.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RUS71381.1 - 0.0018 18.2 3.8 0.0048 16.9 3.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PI_PP_I PF18363.1 RUS71381.1 - 0.044 14.0 2.2 0.13 12.5 2.2 1.8 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain zf-UBP_var PF17807.1 RUS71381.1 - 0.066 13.0 1.0 0.16 11.8 1.0 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger GLTSCR1 PF15249.6 RUS71381.1 - 0.49 10.9 6.9 0.35 11.3 4.6 2.0 2 0 0 2 2 1 0 Conserved region of unknown function on GLTSCR protein eIF3_N PF09440.10 RUS71381.1 - 0.94 9.9 6.9 2.8 8.4 6.9 1.8 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain zf-C3HC4_3 PF13920.6 RUS71381.1 - 1.8 8.5 18.4 0.3 11.0 7.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) M PF02370.16 RUS71381.1 - 2.8 8.8 13.5 8.6 7.3 2.6 4.4 3 1 0 3 3 3 0 M protein repeat zf-C3H2C3 PF17122.5 RUS71381.1 - 4.3 7.5 10.3 0.067 13.2 2.4 2.1 2 0 0 2 2 1 0 Zinc-finger EF-hand_8 PF13833.6 RUS71383.1 - 7.9e-09 35.2 0.8 8.5e-07 28.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS71383.1 - 5.2e-08 31.9 1.0 2e-05 23.8 0.5 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS71383.1 - 2e-07 30.4 1.4 6.2e-06 25.7 0.8 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RUS71383.1 - 4.4e-07 30.3 0.2 9.5e-07 29.2 0.2 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS71383.1 - 0.013 15.0 0.3 0.028 13.9 0.3 1.6 1 0 0 1 1 1 0 EF hand CCDC53 PF10152.9 RUS71384.1 - 4.4e-46 157.1 0.0 7.2e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Mito_fiss_reg PF05308.11 RUS71384.1 - 10 6.1 16.2 1.3 9.1 12.0 1.6 1 1 1 2 2 2 0 Mitochondrial fission regulator Somatomedin_B PF01033.17 RUS71388.1 - 0.0024 18.2 11.7 0.0047 17.3 11.7 1.5 1 0 0 1 1 1 1 Somatomedin B domain 7tm_2 PF00002.24 RUS71389.1 - 7.6e-11 41.8 7.1 1.3e-10 41.0 7.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) zf-MYND PF01753.18 RUS71390.1 - 2e-09 37.4 19.9 4.5e-09 36.2 19.9 1.7 1 0 0 1 1 1 1 MYND finger HBD PF18534.1 RUS71390.1 - 0.25 11.5 4.5 0.55 10.4 0.2 2.8 3 0 0 3 3 3 0 Helical bundle domain zf-HIT PF04438.16 RUS71390.1 - 0.55 10.1 9.1 1.2 9.1 9.1 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 RUS71390.1 - 8.3 6.8 13.0 19 5.6 13.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HAGH_C PF16123.5 RUS71391.1 - 4.7e-12 46.2 0.1 1.9e-11 44.3 0.0 1.9 1 1 1 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RUS71391.1 - 4.1e-10 40.0 1.8 2.8e-09 37.3 1.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS71391.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RPOL_N PF14700.6 RUS71391.1 - 0.039 13.4 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Lactamase_B_3 PF13483.6 RUS71391.1 - 0.047 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PRMT5_C PF17286.2 RUS71392.1 - 1.5e-05 25.0 0.1 4.1e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PrmA PF06325.13 RUS71392.1 - 1.8e-05 24.3 0.2 1.8e-05 24.3 0.2 1.9 2 1 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) YL1 PF05764.13 RUS71392.1 - 0.00032 20.9 12.1 0.00045 20.4 12.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Methyltransf_23 PF13489.6 RUS71392.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS71392.1 - 0.0022 18.6 0.0 0.0072 17.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain ASC PF00858.24 RUS71392.1 - 0.0071 15.4 1.4 0.0096 14.9 1.4 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel FtsJ PF01728.19 RUS71392.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tim54 PF11711.8 RUS71392.1 - 0.032 13.0 7.3 0.046 12.5 7.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Eapp_C PF10238.9 RUS71392.1 - 0.033 14.3 4.8 0.06 13.4 4.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Methyltransf_31 PF13847.6 RUS71392.1 - 0.041 13.7 0.2 0.22 11.3 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RUS71392.1 - 0.041 13.4 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF3464 PF11947.8 RUS71392.1 - 0.087 12.6 11.8 0.17 11.6 11.8 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Methyltransf_9 PF08003.11 RUS71392.1 - 0.12 11.3 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 RUS71392.1 - 0.18 12.5 0.0 0.7 10.6 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain SR-25 PF10500.9 RUS71392.1 - 0.66 9.5 39.0 1.5 8.4 39.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Casc1 PF12366.8 RUS71392.1 - 0.73 9.3 14.7 5.3 6.5 16.1 1.7 2 0 0 2 2 1 0 Cancer susceptibility candidate 1 DUF4770 PF15994.5 RUS71392.1 - 1 9.6 14.9 2 8.6 14.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Cellulose_synt PF03552.14 RUS71392.1 - 1.1 7.7 5.2 1.4 7.3 5.2 1.2 1 0 0 1 1 1 0 Cellulose synthase AF-4 PF05110.13 RUS71392.1 - 1.4 6.9 25.3 1.8 6.5 25.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 RUS71392.1 - 1.5 7.5 5.3 2 7.1 5.3 1.2 1 0 0 1 1 1 0 Presenilin DUF1764 PF08576.10 RUS71392.1 - 2.3 9.2 21.8 0.75 10.7 18.5 1.8 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 RUS71392.1 - 3.7 7.2 12.2 6.8 6.4 12.2 1.3 1 0 0 1 1 1 0 Connexin DUF3807 PF12720.7 RUS71392.1 - 4.2 7.6 18.9 8.8 6.6 18.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 RUS71392.1 - 5.7 6.7 16.8 2.1 8.1 14.3 1.5 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 RUS71392.1 - 6.1 5.0 12.6 9.6 4.4 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Jak1_Phl PF17887.1 RUS71392.1 - 6.2 6.8 13.7 14 5.6 13.7 1.6 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Cas_Csy4 PF09618.10 RUS71392.1 - 6.2 6.9 10.6 16 5.6 10.6 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Sec62 PF03839.16 RUS71392.1 - 8.4 5.8 17.3 17 4.9 17.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DDE_Tnp_4 PF13359.6 RUS71393.1 - 2e-40 138.0 0.0 2.7e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS71393.1 - 1.9e-12 47.3 0.0 8.3e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS71393.1 - 2.6e-10 40.3 0.1 7.8e-09 35.5 0.1 2.3 1 1 0 1 1 1 1 Transposase DDE domain SeqA_N PF17206.3 RUS71394.1 - 0.45 9.9 0.1 0.45 9.9 0.1 1.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain YscO PF07321.12 RUS71395.1 - 0.00027 20.9 11.0 0.00027 20.9 11.0 3.1 1 1 2 3 3 2 1 Type III secretion protein YscO MCPsignal PF00015.21 RUS71395.1 - 0.0012 18.7 17.0 0.0071 16.2 6.5 2.8 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 RUS71395.1 - 0.0058 15.9 17.7 0.01 15.1 6.0 2.5 1 1 0 2 2 2 2 TMPIT-like protein DUF4559 PF15112.6 RUS71395.1 - 0.0098 15.6 22.3 0.15 11.7 12.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4559) Laminin_II PF06009.12 RUS71395.1 - 0.011 15.7 25.3 0.015 15.3 8.2 3.3 1 1 2 3 3 3 0 Laminin Domain II MetOD2 PF18548.1 RUS71395.1 - 0.012 15.7 12.3 0.83 9.8 0.8 3.8 2 1 0 3 3 3 0 Metanogen output domain 2 FlaC_arch PF05377.11 RUS71395.1 - 0.06 13.8 8.4 0.26 11.7 0.1 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 RUS71395.1 - 0.062 12.8 32.7 1.8 8.0 21.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TcdB_N PF12918.7 RUS71395.1 - 0.086 13.1 10.5 0.8 10.0 0.3 4.2 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain Noelin-1 PF12308.8 RUS71395.1 - 0.1 12.6 10.4 1.6 8.7 1.6 3.2 2 1 2 4 4 4 0 Neurogenesis glycoprotein DUF3450 PF11932.8 RUS71395.1 - 0.18 11.1 27.4 0.079 12.3 11.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 RUS71395.1 - 0.27 11.5 16.9 2 8.8 1.6 4.4 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 RUS71395.1 - 0.37 10.5 26.7 0.062 13.0 17.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DegS PF05384.11 RUS71395.1 - 0.55 9.7 22.1 0.48 9.9 0.7 3.1 1 1 2 3 3 3 0 Sensor protein DegS Atg14 PF10186.9 RUS71395.1 - 0.6 9.1 27.4 0.22 10.6 15.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Duo1 PF08651.10 RUS71395.1 - 0.68 9.7 6.2 0.91 9.3 0.6 3.6 3 1 1 4 4 4 0 DASH complex subunit Duo1 DUF4763 PF15960.5 RUS71395.1 - 0.84 8.9 17.9 17 4.6 17.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Exonuc_VII_L PF02601.15 RUS71395.1 - 1.2 8.7 20.6 1.8e+02 1.5 20.6 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin_2 PF14523.6 RUS71395.1 - 1.2 9.6 24.5 4.9 7.6 3.7 3.4 1 1 1 3 3 3 0 Syntaxin-like protein EzrA PF06160.12 RUS71395.1 - 1.7 6.8 30.2 5.9 5.0 12.9 2.4 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 RUS71395.1 - 1.9 8.5 20.1 1.6 8.8 3.0 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE_C PF12352.8 RUS71395.1 - 2.2 8.6 11.8 18 5.7 0.5 4.2 3 2 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DASH_Dam1 PF08653.10 RUS71395.1 - 2.3 8.1 9.4 13 5.7 0.0 4.2 4 1 1 5 5 5 0 DASH complex subunit Dam1 ISG65-75 PF11727.8 RUS71395.1 - 2.4 7.3 28.4 1.1 8.4 10.0 2.9 1 1 1 3 3 3 0 Invariant surface glycoprotein V-ATPase_G_2 PF16999.5 RUS71395.1 - 2.8 8.4 29.6 0.047 14.1 7.3 3.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Occludin_ELL PF07303.13 RUS71395.1 - 2.8 8.7 18.1 6.7 7.5 2.1 4.1 1 1 1 3 3 3 0 Occludin homology domain DUF883 PF05957.13 RUS71395.1 - 3.3 8.4 26.3 0.49 11.0 4.0 4.4 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Golgin_A5 PF09787.9 RUS71395.1 - 4.4 6.7 28.3 3.7 6.9 12.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 T3SSipB PF16535.5 RUS71395.1 - 5.5 7.4 34.6 1 9.8 14.2 3.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB Fib_alpha PF08702.10 RUS71395.1 - 6.3 7.0 23.5 13 6.0 2.6 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RUS71395.1 - 7.7 5.3 32.8 28 3.5 10.2 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 RUS71395.1 - 8.2 5.6 25.8 7.5 5.8 10.9 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein YkyA PF10368.9 RUS71395.1 - 8.3 6.0 34.8 36 4.0 24.8 3.2 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF2203 PF09969.9 RUS71395.1 - 8.5 7.1 21.8 8.1 7.2 6.7 3.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 RUS71395.1 - 8.6 6.6 30.4 0.88 9.8 14.6 3.4 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Laminin_EGF PF00053.24 RUS71396.1 - 2.2e-93 306.2 243.7 1.3e-10 41.3 11.3 13.2 13 0 0 13 13 12 12 Laminin EGF domain DUF4085 PF13315.6 RUS71396.1 - 0.071 12.7 0.5 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Prominin PF05478.11 RUS71396.1 - 0.16 9.9 6.9 0.23 9.3 6.9 1.2 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 RUS71396.1 - 0.41 10.6 12.7 0.18 11.8 5.1 2.5 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 RUS71396.1 - 1.4 9.4 9.4 58 4.3 0.0 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 RUS71396.1 - 2.2 7.9 8.9 3 7.5 2.2 2.4 1 1 0 2 2 2 0 LXG domain of WXG superfamily FUSC PF04632.12 RUS71396.1 - 2.6 6.5 3.9 3.7 6.0 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 RUS71396.1 - 2.9 8.3 12.7 10 6.5 12.7 1.9 1 1 0 1 1 1 0 Fez1 EzrA PF06160.12 RUS71396.1 - 4.3 5.4 15.0 0.84 7.7 1.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FIVAR PF07554.13 RUS71396.1 - 5.2 7.9 9.1 2 9.2 0.0 2.9 3 0 0 3 3 2 0 FIVAR domain V-SNARE PF05008.15 RUS71396.1 - 5.3 7.5 9.2 7.2 7.1 1.0 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.11 RUS71396.1 - 7.4 7.1 12.7 3.5 8.1 1.0 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 RUS71396.1 - 7.4 4.3 5.8 11 3.8 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 RUS71396.1 - 8.1 6.9 9.6 1 9.8 0.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 RUS71396.1 - 8.9 6.4 9.1 15 5.6 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 RUS71396.1 - 9.5 6.1 7.0 25 4.7 0.2 2.7 2 1 1 3 3 3 0 Nsp1-like C-terminal region SOGA PF11365.8 RUS71399.1 - 5.2e-09 37.1 13.5 5.2e-09 37.1 13.5 8.6 5 3 4 9 9 9 5 Protein SOGA HOOK PF05622.12 RUS71399.1 - 0.0034 15.6 3.3 0.0034 15.6 3.3 7.1 2 2 4 7 7 7 3 HOOK protein Dmrt1 PF12374.8 RUS71401.1 - 1.1 9.7 6.6 13 6.3 0.8 2.7 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 ABC2_membrane PF01061.24 RUS71402.1 - 3.7e-36 124.5 9.6 6.6e-36 123.7 9.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 RUS71402.1 - 4.6 6.3 20.0 3.8 6.5 18.2 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein Glyco_transf_92 PF01697.27 RUS71403.1 - 8.2e-17 61.7 0.1 1e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS71403.1 - 0.00071 20.1 0.1 0.047 14.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2310 PF10071.9 RUS71404.1 - 1.9e-05 24.0 2.2 0.65 9.2 0.1 3.2 1 1 2 3 3 3 3 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Plug_translocon PF10559.9 RUS71404.1 - 4.9e-05 23.1 0.2 1.8e+02 2.1 0.0 6.6 7 0 0 7 7 7 0 Plug domain of Sec61p DUF3155 PF11352.8 RUS71404.1 - 0.0011 19.4 0.3 71 3.9 0.0 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF3155) DUF2480 PF10652.9 RUS71404.1 - 0.068 13.1 12.3 1.1e+02 2.6 0.0 6.6 7 0 0 7 7 7 0 Protein of unknown function (DUF2480) DUF5500 PF17604.2 RUS71405.1 - 0.042 13.9 0.0 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5500) DUF4893 PF16233.5 RUS71405.1 - 0.085 12.5 1.9 5.5 6.6 1.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4893) IN_DBD_C PF00552.21 RUS71405.1 - 0.2 11.0 3.2 46 3.4 0.1 3.5 3 0 0 3 3 3 0 Integrase DNA binding domain 2Fe-2S_Ferredox PF11591.8 RUS71405.1 - 1.3 9.0 9.5 14 5.7 0.2 4.2 4 0 0 4 4 4 0 Ferredoxin chloroplastic transit peptide Syntaxin-6_N PF09177.11 RUS71406.1 - 2.2e-12 47.4 17.4 0.019 15.5 5.4 6.5 1 1 4 5 5 5 3 Syntaxin 6, N-terminal CENP-Q PF13094.6 RUS71406.1 - 3.4e-07 30.6 0.2 0.0028 17.9 1.3 3.0 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit TolA_bind_tri PF16331.5 RUS71406.1 - 4.7e-06 26.6 12.8 1.6 8.9 0.3 5.6 1 1 5 6 6 6 1 TolA binding protein trimerisation DASH_Hsk3 PF08227.11 RUS71406.1 - 8.3e-06 26.1 14.4 0.3 11.5 0.8 6.3 3 1 2 6 6 6 1 DASH complex subunit Hsk3 like MscS_porin PF12795.7 RUS71406.1 - 7.2e-05 22.5 11.5 0.0026 17.4 7.3 2.4 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Sec2p PF06428.11 RUS71406.1 - 8.5e-05 22.4 21.7 0.2 11.6 1.4 5.5 1 1 5 6 6 6 2 GDP/GTP exchange factor Sec2p APG6_N PF17675.1 RUS71406.1 - 9.9e-05 22.9 2.2 0.0017 18.9 2.2 2.1 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF1664 PF07889.12 RUS71406.1 - 0.00014 21.9 17.9 0.035 14.1 9.8 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) CCDC144C PF14915.6 RUS71406.1 - 0.00015 21.0 6.0 0.037 13.1 2.7 2.8 1 1 1 3 3 3 1 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.19 RUS71406.1 - 0.00015 19.7 6.0 0.00031 18.7 6.0 1.4 1 1 0 1 1 1 1 Myosin tail MobC PF05713.11 RUS71406.1 - 0.00031 21.1 16.0 9.2 6.8 0.1 6.1 5 1 0 6 6 6 0 Bacterial mobilisation protein (MobC) DUF3450 PF11932.8 RUS71406.1 - 0.00034 20.0 12.4 0.004 16.5 7.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) COG2 PF06148.11 RUS71406.1 - 0.00048 20.2 8.4 0.49 10.5 1.6 3.2 1 1 3 4 4 4 2 COG (conserved oligomeric Golgi) complex component, COG2 FPP PF05911.11 RUS71406.1 - 0.00072 17.9 6.6 0.0013 17.1 6.6 1.3 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil Filament PF00038.21 RUS71406.1 - 0.00079 19.1 6.9 0.016 14.8 3.1 2.3 1 1 1 2 2 2 1 Intermediate filament protein FH2 PF02181.23 RUS71406.1 - 0.00085 18.5 6.4 0.024 13.8 6.0 2.2 1 1 0 1 1 1 1 Formin Homology 2 Domain FlaC_arch PF05377.11 RUS71406.1 - 0.00085 19.7 9.0 1.4 9.3 0.6 4.6 1 1 5 6 6 6 1 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 RUS71406.1 - 0.00098 18.8 5.4 0.0056 16.3 0.7 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Tropomyosin PF00261.20 RUS71406.1 - 0.00099 18.5 0.3 0.0022 17.4 0.3 1.6 1 1 0 1 1 1 1 Tropomyosin DUF16 PF01519.16 RUS71406.1 - 0.002 18.6 17.5 0.23 12.0 4.8 3.1 1 1 2 3 3 3 2 Protein of unknown function DUF16 ATG16 PF08614.11 RUS71406.1 - 0.0025 18.0 10.6 0.6 10.3 4.9 2.9 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) HOOK PF05622.12 RUS71406.1 - 0.0026 16.0 12.2 0.021 13.0 7.8 2.0 1 1 1 2 2 2 2 HOOK protein Sec34 PF04136.15 RUS71406.1 - 0.0031 17.4 15.0 0.13 12.1 3.2 3.2 1 1 2 3 3 3 2 Sec34-like family DHR10 PF18595.1 RUS71406.1 - 0.0035 17.4 7.6 0.029 14.4 2.0 2.8 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain IFT57 PF10498.9 RUS71406.1 - 0.0037 16.3 8.3 0.035 13.1 4.8 2.5 1 1 2 3 3 3 1 Intra-flagellar transport protein 57 PhaP_Bmeg PF09602.10 RUS71406.1 - 0.004 17.1 12.4 0.97 9.3 2.7 3.8 1 1 3 4 4 4 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TMPIT PF07851.13 RUS71406.1 - 0.0048 16.2 7.7 0.12 11.6 1.9 2.2 1 1 1 2 2 2 1 TMPIT-like protein Sulfatase_C PF14707.6 RUS71406.1 - 0.0059 17.3 3.0 5 7.9 0.9 3.9 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase Seryl_tRNA_N PF02403.22 RUS71406.1 - 0.0061 16.8 6.0 0.51 10.6 2.0 3.2 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 RUS71406.1 - 0.0064 15.9 5.8 0.023 14.1 4.8 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 RUS71406.1 - 0.0084 16.1 13.4 0.079 13.0 6.0 2.8 1 1 2 3 3 3 1 Laminin Domain II AAA_13 PF13166.6 RUS71406.1 - 0.0092 14.7 4.8 0.012 14.3 4.8 1.2 1 0 0 1 1 1 1 AAA domain KxDL PF10241.9 RUS71406.1 - 0.01 16.1 13.0 0.92 9.8 2.5 3.7 1 1 1 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.11 RUS71406.1 - 0.011 14.6 9.6 0.057 12.3 6.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 RUS71406.1 - 0.012 15.4 4.9 0.1 12.3 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MbeD_MobD PF04899.12 RUS71406.1 - 0.012 15.8 3.3 10 6.4 0.1 3.8 1 1 5 6 6 6 0 MbeD/MobD like CdvA PF18822.1 RUS71406.1 - 0.012 15.4 8.5 0.2 11.5 1.2 3.1 1 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF812 PF05667.11 RUS71406.1 - 0.013 14.4 7.0 0.63 8.8 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 RUS71406.1 - 0.015 15.0 9.2 0.055 13.1 9.2 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Rab5-bind PF09311.11 RUS71406.1 - 0.016 14.6 12.4 1.5 8.1 4.1 2.9 1 1 2 3 3 3 0 Rabaptin-like protein DUF4795 PF16043.5 RUS71406.1 - 0.02 14.5 16.8 0.97 9.0 4.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) BST2 PF16716.5 RUS71406.1 - 0.02 15.4 10.7 0.086 13.4 0.9 3.2 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 Sigma54_AID PF00309.20 RUS71406.1 - 0.028 14.3 6.4 7.8 6.4 0.0 4.9 5 1 0 5 5 5 0 Sigma-54 factor, Activator interacting domain (AID) CENP-F_leu_zip PF10473.9 RUS71406.1 - 0.029 14.4 5.8 0.11 12.5 3.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 RUS71406.1 - 0.033 14.3 7.5 0.071 13.2 2.9 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase T3SSipB PF16535.5 RUS71406.1 - 0.036 14.5 7.4 0.79 10.2 2.6 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB HrpB7 PF09486.10 RUS71406.1 - 0.037 14.4 3.2 12 6.2 2.0 2.8 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2313 PF10076.9 RUS71406.1 - 0.038 13.8 5.4 18 5.1 0.2 4.1 1 1 5 6 6 6 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF493 PF04359.14 RUS71406.1 - 0.042 14.4 2.5 5.5 7.6 0.1 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF493) Prefoldin PF02996.17 RUS71406.1 - 0.045 13.7 9.9 6.5 6.7 0.6 4.0 1 1 2 4 4 4 0 Prefoldin subunit COMM_domain PF07258.14 RUS71406.1 - 0.049 13.8 14.3 8.5 6.6 0.3 5.1 3 2 1 5 5 5 0 COMM domain HMMR_N PF15905.5 RUS71406.1 - 0.053 13.0 9.5 0.13 11.7 9.5 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 RUS71406.1 - 0.053 13.7 8.8 1.9 8.6 5.5 3.4 1 1 1 2 2 2 0 Tropomyosin like MAD PF05557.13 RUS71406.1 - 0.054 11.9 9.3 0.55 8.5 2.5 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF2968 PF11180.8 RUS71406.1 - 0.055 13.1 14.2 0.11 12.1 6.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Phage_GP20 PF06810.11 RUS71406.1 - 0.08 12.8 13.4 8.8 6.1 11.5 3.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 RUS71406.1 - 0.082 13.4 32.0 53 4.4 3.9 4.5 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS71406.1 - 0.082 13.2 20.5 1.4e+03 -0.4 16.1 3.8 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) JIP_LZII PF16471.5 RUS71406.1 - 0.11 12.7 4.5 19 5.5 0.5 3.4 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II Prefoldin_2 PF01920.20 RUS71406.1 - 0.12 12.4 8.8 5.3 7.0 0.5 3.8 1 1 2 3 3 3 0 Prefoldin subunit HAP1_N PF04849.13 RUS71406.1 - 0.13 11.4 11.1 1.4 8.0 4.9 2.8 1 1 2 3 3 3 0 HAP1 N-terminal conserved region TMF_TATA_bd PF12325.8 RUS71406.1 - 0.14 12.3 1.9 1.3 9.2 1.1 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding EzrA PF06160.12 RUS71406.1 - 0.16 10.1 11.6 23 3.0 0.2 2.2 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 RUS71406.1 - 0.16 12.1 15.5 0.73 10.0 4.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.11 RUS71406.1 - 0.17 10.8 7.7 0.21 10.4 7.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF641 PF04859.12 RUS71406.1 - 0.17 12.3 5.2 1.6 9.0 0.5 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Takusan PF04822.13 RUS71406.1 - 0.17 11.8 2.3 3.4 7.6 0.7 2.9 1 1 2 3 3 3 0 Takusan DUF4201 PF13870.6 RUS71406.1 - 0.19 11.5 8.6 5.1 6.8 9.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4763 PF15960.5 RUS71406.1 - 0.2 10.9 17.9 0.051 12.9 1.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) T3SS_needle_E PF08988.10 RUS71406.1 - 0.21 11.7 6.7 9 6.5 0.1 4.2 2 1 4 6 6 6 0 Type III secretion system, cytoplasmic E component of needle SlyX PF04102.12 RUS71406.1 - 0.21 12.2 21.2 0.32 11.6 2.4 4.1 1 1 3 4 4 4 0 SlyX DivIC PF04977.15 RUS71406.1 - 0.22 11.3 10.4 6.9 6.5 0.2 3.9 1 1 2 4 4 4 0 Septum formation initiator CHASE3 PF05227.13 RUS71406.1 - 0.23 11.4 3.6 1.7 8.6 1.0 2.4 1 1 1 2 2 2 0 CHASE3 domain ArsR PF09824.9 RUS71406.1 - 0.23 11.0 8.9 4.3 6.9 0.6 3.0 1 1 2 3 3 3 0 ArsR transcriptional regulator TRAF_BIRC3_bd PF16673.5 RUS71406.1 - 0.27 11.1 4.0 5.2 6.9 0.0 3.5 1 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Fez1 PF06818.15 RUS71406.1 - 0.28 11.6 3.3 0.56 10.6 3.3 1.6 1 1 0 1 1 1 0 Fez1 DUF2451 PF10474.9 RUS71406.1 - 0.28 10.9 5.5 1.7 8.4 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2451) KELK PF15796.5 RUS71406.1 - 0.3 11.6 4.5 6.2 7.4 1.2 3.3 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ADIP PF11559.8 RUS71406.1 - 0.32 11.1 9.9 1.6 8.8 5.9 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 RUS71406.1 - 0.34 11.6 5.9 14 6.4 2.6 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Atg14 PF10186.9 RUS71406.1 - 0.37 9.8 9.8 0.44 9.6 7.1 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 RUS71406.1 - 0.47 10.6 9.4 1.8 8.7 6.1 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LXG PF04740.12 RUS71406.1 - 0.54 9.9 17.9 0.73 9.5 4.7 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF4854 PF16146.5 RUS71406.1 - 0.56 10.6 3.8 1.8 8.9 1.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4854) Tup_N PF08581.10 RUS71406.1 - 0.56 10.5 9.7 2.1 8.7 1.2 3.3 1 1 3 4 4 4 0 Tup N-terminal DUF3461 PF11944.8 RUS71406.1 - 0.6 10.2 21.1 54 3.9 0.3 4.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3461) Blo-t-5 PF11642.8 RUS71406.1 - 0.61 10.1 11.9 17 5.4 0.4 4.5 1 1 3 4 4 4 0 Mite allergen Blo t 5 SYCE1 PF15233.6 RUS71406.1 - 0.77 9.8 8.3 1.2 9.1 3.2 2.3 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 Prominin PF05478.11 RUS71406.1 - 0.85 7.5 11.9 0.81 7.6 6.8 1.8 1 1 1 2 2 2 0 Prominin Med9 PF07544.13 RUS71406.1 - 0.95 9.6 13.8 16 5.7 1.2 3.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YEATS PF03366.16 RUS71406.1 - 1 9.4 6.7 1.5e+03 -0.7 6.7 4.4 1 1 0 1 1 1 0 YEATS family SKA1 PF07160.12 RUS71406.1 - 1.3 8.9 14.4 4.9 6.9 8.4 2.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Cluap1 PF10234.9 RUS71406.1 - 1.4 8.3 9.4 4.2 6.7 8.2 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 FlgN PF05130.12 RUS71406.1 - 1.4 9.4 9.6 3.4 8.2 6.8 2.6 1 1 1 2 2 2 0 FlgN protein AIP3 PF03915.13 RUS71406.1 - 1.6 7.7 17.4 4.9 6.1 15.9 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 PEP-utilisers_N PF05524.13 RUS71406.1 - 1.7 8.9 3.7 74 3.6 3.7 3.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal MCPsignal PF00015.21 RUS71406.1 - 1.8 8.4 7.8 8.1 6.2 3.6 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PspA_IM30 PF04012.12 RUS71406.1 - 2.8 7.5 8.0 1.4 8.5 0.9 2.6 1 1 2 3 3 3 0 PspA/IM30 family LOH1CR12 PF10158.9 RUS71406.1 - 3.1 7.8 13.1 5.7 7.0 4.1 2.9 1 1 2 3 3 3 0 Tumour suppressor protein Fzo_mitofusin PF04799.13 RUS71406.1 - 4.4 6.8 11.4 3.1 7.3 2.6 2.8 1 1 2 3 3 3 0 fzo-like conserved region JMY PF15871.5 RUS71406.1 - 4.5 6.5 10.0 13 5.0 3.3 2.5 1 1 1 2 2 2 0 Junction-mediating and -regulatory protein USP8_interact PF08941.10 RUS71406.1 - 8.2 6.2 7.9 12 5.7 2.6 2.3 1 1 1 2 2 2 0 USP8 interacting EMP24_GP25L PF01105.24 RUS71406.1 - 8.3 6.3 11.1 2.8e+02 1.3 7.3 3.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD SANTA PF09133.10 RUS71407.1 - 2.5e-19 69.6 0.0 7.8e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 RUS71407.1 - 2e-05 24.7 0.3 4.3e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RBB1NT PF08169.11 RUS71407.1 - 0.12 12.5 3.5 1.6 9.0 0.3 3.3 3 0 0 3 3 3 0 RBB1NT (NUC162) domain BAH PF01426.18 RUS71409.1 - 3.1e-14 52.9 0.0 7.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 BAH domain OB_NTP_bind PF07717.16 RUS71410.1 - 2.5e-18 66.2 0.0 6.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RUS71410.1 - 3.6e-18 65.8 0.4 9.5e-18 64.5 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RUS71410.1 - 2.6e-15 56.7 0.0 6.2e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 RUS71410.1 - 4.7e-13 49.4 0.2 1.3e-12 48.0 0.2 1.8 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 RUS71410.1 - 4.2e-10 39.7 0.0 7.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCCH_4 PF18044.1 RUS71410.1 - 0.00013 21.7 2.7 0.00029 20.6 2.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RUS71410.1 - 0.0002 21.3 5.6 0.0002 21.3 5.6 2.1 2 0 0 2 2 2 1 Zinc finger domain UBA PF00627.31 RUS71410.1 - 0.00032 20.5 0.0 0.00097 19.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Torus PF16131.5 RUS71410.1 - 0.0004 21.0 0.1 0.0012 19.5 0.1 1.7 1 0 0 1 1 1 1 Torus domain AAA_14 PF13173.6 RUS71410.1 - 0.0016 18.5 0.3 0.019 15.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS71410.1 - 0.0068 16.7 0.3 0.023 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain zf-CCCH PF00642.24 RUS71410.1 - 0.0083 16.0 2.4 0.0083 16.0 2.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_22 PF13401.6 RUS71410.1 - 0.0087 16.3 0.1 0.029 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 RUS71410.1 - 0.03 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 RUS71410.1 - 0.049 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 RUS71410.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MerR-DNA-bind PF09278.11 RUS71410.1 - 0.087 13.4 0.2 0.38 11.3 0.0 2.1 2 0 0 2 2 1 0 MerR, DNA binding zf-CCCH_2 PF14608.6 RUS71410.1 - 0.1 13.1 2.4 0.22 12.0 2.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MFS_1 PF07690.16 RUS71411.1 - 8.3e-33 113.8 37.3 3.3e-18 65.8 14.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 RUS71411.1 - 0.00012 20.5 0.8 0.00073 18.0 0.1 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TUDOR PF00567.24 RUS71412.1 - 3.2e-104 343.6 4.9 8.7e-26 90.4 0.0 6.4 6 0 0 6 6 6 5 Tudor domain RRM_1 PF00076.22 RUS71412.1 - 3.1e-14 52.5 0.0 9.5e-14 51.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS71412.1 - 9.4e-10 38.2 0.2 5.4e-09 35.7 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Agenet PF05641.12 RUS71412.1 - 8.4e-08 32.6 6.5 0.33 11.5 0.1 5.5 5 0 0 5 5 5 2 Agenet domain zf-MYND PF01753.18 RUS71412.1 - 7.3e-07 29.2 14.2 7.3e-07 29.2 14.2 2.0 2 0 0 2 2 2 1 MYND finger DUF4537 PF15057.6 RUS71412.1 - 0.0026 17.8 0.1 11 6.1 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 RUS71412.1 - 0.012 15.2 0.1 1.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Tudor_4 PF18358.1 RUS71412.1 - 0.77 9.4 4.7 25 4.5 0.0 3.8 5 0 0 5 5 5 0 Histone methyltransferase Tudor domain BAR PF03114.18 RUS71413.1 - 5.2e-18 65.6 9.3 7.4e-18 65.1 9.3 1.1 1 0 0 1 1 1 1 BAR domain GIT1_C PF12205.8 RUS71413.1 - 0.0016 18.6 4.0 0.66 10.1 0.1 3.1 3 0 0 3 3 3 2 G protein-coupled receptor kinase-interacting protein 1 C term Vps5 PF09325.10 RUS71413.1 - 0.0016 18.0 6.7 0.0061 16.1 6.7 1.8 1 1 0 1 1 1 1 Vps5 C terminal like DUF1280 PF06918.14 RUS71413.1 - 0.0081 15.8 1.5 0.016 14.8 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1280) BAR_3 PF16746.5 RUS71413.1 - 0.012 15.4 10.6 0.028 14.1 10.6 1.8 1 1 0 1 1 1 0 BAR domain of APPL family V_ATPase_I PF01496.19 RUS71413.1 - 0.029 12.3 6.5 0.034 12.1 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peroxidase_2 PF01328.17 RUS71413.1 - 0.059 13.9 0.7 0.092 13.3 0.7 1.5 1 1 0 1 1 1 0 Peroxidase, family 2 Seryl_tRNA_N PF02403.22 RUS71413.1 - 1.4 9.2 9.8 0.4 10.9 2.3 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PCO_ADO PF07847.12 RUS71414.1 - 8.1e-51 172.3 0.0 9.7e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO PsiA PF06952.11 RUS71414.1 - 0.033 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 PsiA protein CDO_I PF05995.12 RUS71414.1 - 0.086 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I DALR_2 PF09190.11 RUS71415.1 - 4.1e-06 27.2 0.0 8.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DALR domain KIAA1430 PF13879.6 RUS71416.1 - 1.3e-09 38.8 6.4 1.3e-09 38.8 6.4 3.3 3 2 0 3 3 3 1 KIAA1430 homologue zf-C2H2_jaz PF12171.8 RUS71417.1 - 4.6e-07 30.0 1.5 8.6e-07 29.1 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS71417.1 - 1.7e-06 28.2 1.4 2.7e-06 27.6 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 RUS71417.1 - 0.00023 20.8 1.0 0.0004 20.1 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger Herpes_IE1 PF07340.11 RUS71417.1 - 0.0059 15.6 0.7 0.0074 15.2 0.7 1.2 1 0 0 1 1 1 1 Cytomegalovirus IE1 protein PTPRCAP PF15713.5 RUS71417.1 - 0.046 14.0 11.0 0.85 9.9 4.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated zf-C2H2 PF00096.26 RUS71417.1 - 0.14 12.7 1.0 0.28 11.7 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1168 PF06658.12 RUS71417.1 - 2.8 7.8 23.7 0.18 11.6 15.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Methyltransf_32 PF13679.6 RUS71418.1 - 2.3e-09 37.5 7.9 1.9e-07 31.2 7.9 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS71418.1 - 1.4e-08 34.7 0.1 3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 RUS71418.1 - 5.8e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.14 RUS71418.1 - 0.00011 21.9 2.5 0.088 12.3 2.2 2.8 1 1 1 2 2 2 2 Methyltransferase TRM13 GST_C PF00043.25 RUS71418.1 - 0.00014 22.0 0.0 0.00044 20.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MTS PF05175.14 RUS71418.1 - 0.00055 19.5 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RUS71418.1 - 0.011 16.4 0.1 0.039 14.7 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 RUS71418.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase GST_C_3 PF14497.6 RUS71418.1 - 0.022 15.0 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.9 RUS71418.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase Pan3_PK PF18101.1 RUS71419.1 - 1.8e-58 196.4 0.1 3.3e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 RUS71419.1 - 0.00032 20.2 0.0 0.015 14.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain SMRP1 PF15181.6 RUS71419.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 SelP_N PF04592.14 RUS71419.1 - 0.74 9.2 17.6 1.3 8.3 17.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region 7tm_1 PF00001.21 RUS71420.1 - 1.3e-17 64.0 14.4 1.5e-11 44.2 5.0 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 RUS71420.1 - 0.012 15.9 3.3 0.064 13.6 1.2 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF2615 PF11027.8 RUS71420.1 - 0.17 12.0 0.9 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) ECSCR PF15820.5 RUS71420.1 - 0.26 11.1 1.2 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator cNMP_binding PF00027.29 RUS71421.1 - 1.2e-42 143.9 0.1 1.6e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RUS71421.1 - 2.6e-08 33.4 0.0 5.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SAPS PF04499.15 RUS71421.1 - 4.7 5.9 9.8 0.39 9.5 5.4 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nexin_C PF08628.12 RUS71422.1 - 8.5e-06 26.3 5.7 0.83 10.3 0.1 3.3 3 0 0 3 3 3 3 Sorting nexin C terminal Filaggrin PF03516.13 RUS71422.1 - 2.5e-05 24.9 16.0 1.5 9.6 0.4 4.3 4 0 0 4 4 4 3 Filaggrin DUF615 PF04751.14 RUS71422.1 - 0.00073 19.5 3.9 3.9 7.4 0.1 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF615) YmgD PF16456.5 RUS71422.1 - 0.0097 15.9 2.9 42 4.3 0.0 4.1 4 0 0 4 4 4 0 YmgD protein DUF2956 PF11169.8 RUS71422.1 - 0.0099 16.1 13.7 1.1 9.5 0.9 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF2956) Izumo-Ig PF16706.5 RUS71422.1 - 0.011 15.8 0.0 43 4.3 0.0 3.5 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF2951 PF11166.8 RUS71422.1 - 0.012 15.9 5.0 16 5.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) DUF2242 PF10001.9 RUS71422.1 - 0.014 15.6 0.2 40 4.4 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2242) DUF1218 PF06749.12 RUS71422.1 - 0.022 15.3 0.0 58 4.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) LCE PF14672.6 RUS71422.1 - 0.058 14.0 13.5 22 5.7 0.1 4.8 4 3 2 6 6 4 0 Late cornified envelope FYTT PF07078.11 RUS71422.1 - 0.23 10.8 15.0 1.5 8.1 0.7 3.1 2 1 1 3 3 3 0 Forty-two-three protein DUF4686 PF15742.5 RUS71422.1 - 0.27 10.4 7.5 14 4.6 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4686) Tropomodulin PF03250.14 RUS71422.1 - 0.4 10.7 8.6 2 8.5 0.2 3.7 2 2 1 4 4 4 0 Tropomodulin ZapA PF05164.13 RUS71422.1 - 0.49 10.9 12.6 11 6.6 0.5 3.7 4 0 0 4 4 4 0 Cell division protein ZapA IL5 PF02025.15 RUS71422.1 - 0.84 9.9 5.9 60 4.0 0.2 3.2 3 0 0 3 3 3 0 Interleukin 5 DNA_binding_2 PF13724.6 RUS71422.1 - 1 9.8 11.8 78 3.8 0.2 4.7 4 0 0 4 4 4 0 DNA-binding domain DUF4732 PF15876.5 RUS71423.1 - 7.1e-10 39.2 0.1 2.2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4732) gag_pre-integrs PF13976.6 RUS71423.1 - 0.14 12.1 0.7 20 5.1 0.1 2.9 1 1 1 2 2 2 0 GAG-pre-integrase domain MFS_1 PF07690.16 RUS71426.1 - 2.4e-06 26.7 24.3 9.1e-06 24.8 8.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipocalin_2 PF08212.12 RUS71427.1 - 3.8e-13 49.6 0.0 5.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS71427.1 - 2.3e-07 31.1 0.0 3.2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family T4-Gluco-transf PF09198.10 RUS71427.1 - 0.021 14.4 0.9 5 6.8 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage T4 beta-glucosyltransferase Triabin PF03973.13 RUS71427.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Triabin RNA_pol PF00940.19 RUS71428.1 - 4.6e-154 513.2 0.0 9e-154 512.3 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 RUS71428.1 - 5.7e-11 42.4 5.6 2.4e-10 40.3 0.1 3.2 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 RUS71428.1 - 6.5e-05 23.1 0.0 0.00023 21.3 0.0 2.1 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 RUS71428.1 - 0.00021 21.3 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 RUS71428.1 - 0.019 15.2 0.0 0.063 13.5 0.0 2.0 1 0 0 1 1 1 0 PPR repeat GST_N PF02798.20 RUS71429.1 - 1.1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RUS71429.1 - 3.2e-07 30.7 0.0 6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS71429.1 - 2.3e-05 24.5 0.1 4.5e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS71429.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS71429.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cullin PF00888.22 RUS71430.1 - 3.3e-189 630.5 18.0 4.5e-189 630.1 18.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RUS71430.1 - 1.4e-18 66.7 4.4 1.4e-18 66.7 4.4 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain Stork_head PF10264.9 RUS71430.1 - 0.15 12.3 1.6 0.34 11.1 0.4 2.3 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain RNA_pol_Rpb6 PF01192.22 RUS71431.1 - 1.5e-18 66.5 0.1 2.1e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 GATase1_like PF07090.11 RUS71431.1 - 0.069 12.6 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase APG5 PF04106.12 RUS71432.1 - 3.1e-55 187.2 0.5 4.2e-55 186.8 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 MFS_5 PF05631.14 RUS71434.1 - 2.1e-137 457.8 12.7 3e-137 457.3 12.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 RUS71434.1 - 3.5e-18 65.6 41.8 1.5e-15 57.0 26.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3918 PF13056.6 RUS71434.1 - 0.039 13.6 0.6 0.081 12.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Hydrolase PF00702.26 RUS71435.1 - 3.4e-12 47.1 0.0 4.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS71435.1 - 4.5e-12 46.8 0.0 8.3e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 RUS71435.1 - 0.0044 16.4 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 2 Putative Phosphatase Resolvase PF00239.21 RUS71435.1 - 0.041 14.0 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Resolvase, N terminal domain UMPH-1 PF05822.12 RUS71435.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) zf-MYND PF01753.18 RUS71436.1 - 0.0077 16.3 20.4 0.0077 16.3 20.4 1.9 2 0 0 2 2 2 1 MYND finger VATC PF18716.1 RUS71436.1 - 2 8.4 10.2 4 7.4 10.2 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain BAG PF02179.16 RUS71437.1 - 8.6e-18 64.5 2.4 1.2e-17 64.1 2.4 1.2 1 0 0 1 1 1 1 BAG domain WW PF00397.26 RUS71437.1 - 3.2e-10 39.9 1.1 5.1e-10 39.3 1.1 1.3 1 0 0 1 1 1 1 WW domain DUF2682 PF10909.8 RUS71437.1 - 0.044 14.3 0.3 0.076 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) CCDC53 PF10152.9 RUS71437.1 - 0.57 10.6 4.8 0.96 9.9 1.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PUF PF00806.19 RUS71438.1 - 3.9e-72 234.1 8.1 7.2e-11 41.2 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 RUS71438.1 - 0.017 15.5 1.3 5.1 7.4 0.3 3.8 1 1 2 3 3 3 0 CPL (NUC119) domain HYLS1_C PF15311.6 RUS71438.1 - 0.14 12.9 0.2 0.5 11.2 0.2 1.9 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Somatomedin_B PF01033.17 RUS71440.1 - 9.2e-06 26.0 9.4 9.2e-06 26.0 9.4 2.4 3 0 0 3 3 3 1 Somatomedin B domain SelR PF01641.18 RUS71441.1 - 2.9e-49 166.2 0.0 3.6e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 RUS71441.1 - 0.0017 17.3 0.5 0.12 11.2 0.0 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 RUS71441.1 - 0.025 14.8 0.7 0.069 13.4 0.7 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly XendoU PF09412.10 RUS71442.1 - 1.9e-53 181.4 0.5 2.1e-53 181.2 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU XendoU PF09412.10 RUS71443.1 - 2.1e-64 217.3 2.7 2.9e-64 216.8 2.7 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU Somatomedin_B PF01033.17 RUS71443.1 - 8.6e-17 61.3 45.6 1.4e-08 35.0 17.4 2.6 2 0 0 2 2 2 2 Somatomedin B domain Disintegrin PF00200.23 RUS71444.1 - 9.2e-11 42.4 22.5 9.2e-11 42.4 22.5 3.1 2 1 0 2 2 2 1 Disintegrin Pep_M12B_propep PF01562.19 RUS71444.1 - 0.002 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide MFS_1 PF07690.16 RUS71445.1 - 1.3e-16 60.5 36.9 3.1e-14 52.7 9.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF445 PF04286.12 RUS71446.1 - 0.0093 15.8 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) COMPASS-Shg1 PF05205.12 RUS71446.1 - 0.013 16.2 4.2 0.76 10.5 4.2 2.8 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 SAC3 PF12209.8 RUS71446.1 - 0.035 14.3 0.6 16 5.8 0.1 3.1 2 1 1 3 3 3 0 Leucine permease transcriptional regulator helical domain DUF826 PF05696.11 RUS71446.1 - 0.057 13.5 11.1 2.9e+03 -1.6 11.1 4.4 1 1 0 1 1 1 0 Protein of unknown function (DUF826) COXG PF06240.13 RUS71446.1 - 0.13 12.0 0.0 0.51 10.1 0.0 1.9 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) CUTL PF16557.5 RUS71446.1 - 9.2 6.5 7.2 62 3.9 3.2 3.0 1 1 1 2 2 2 0 CUT1-like DNA-binding domain of SATB RRM_1 PF00076.22 RUS71447.1 - 4.6e-13 48.8 0.0 7.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LEA_2 PF03168.13 RUS71447.1 - 0.11 13.0 0.1 18 5.9 0.0 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein Metallophos PF00149.28 RUS71448.1 - 2.3e-12 47.8 0.1 3.9e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS71448.1 - 1.4e-05 25.4 0.1 0.00016 21.9 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Trypsin_2 PF13365.6 RUS71449.1 - 1.8e-08 35.4 0.8 4.7e-07 30.8 0.0 2.4 1 1 1 2 2 2 1 Trypsin-like peptidase domain G-alpha PF00503.20 RUS71450.1 - 5e-114 381.1 2.5 6.3e-114 380.8 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS71450.1 - 1.1e-13 51.0 3.1 2.6e-10 40.0 0.3 2.9 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS71450.1 - 0.0025 17.2 3.0 0.067 12.5 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RUS71450.1 - 0.035 14.3 0.2 3.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RUS71450.1 - 0.096 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 RUS71450.1 - 0.2 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Syntaxin PF00804.25 RUS71451.1 - 2.7e-16 59.8 1.4 2.7e-16 59.8 1.4 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 RUS71451.1 - 5.7e-14 51.9 0.7 9.2e-14 51.2 0.7 1.4 1 0 0 1 1 1 1 SNARE domain Geminin PF07412.12 RUS71451.1 - 0.051 13.3 2.1 0.064 13.0 2.1 1.1 1 0 0 1 1 1 0 Geminin SKA1 PF07160.12 RUS71451.1 - 0.092 12.6 1.5 0.099 12.5 1.5 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Cyt-b5 PF00173.28 RUS71453.1 - 8.6e-09 35.4 0.0 1.8e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.8 RUS71453.1 - 0.52 10.2 5.1 0.14 12.0 0.6 2.4 3 1 1 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like Dynamin_N PF00350.23 RUS71454.1 - 5.4e-39 134.0 0.1 1.8e-38 132.2 0.1 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RUS71454.1 - 2.3e-05 24.5 0.0 0.0004 20.4 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS71454.1 - 0.00043 19.8 0.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_15 PF13175.6 RUS71454.1 - 0.00075 19.3 0.6 0.3 10.7 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain DUF4268 PF14088.6 RUS71454.1 - 0.0018 18.1 3.5 0.0018 18.1 3.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4268) DUF1593 PF07632.11 RUS71454.1 - 0.0035 16.8 0.0 0.0035 16.8 0.0 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1593) GIT_CC PF16559.5 RUS71454.1 - 0.019 14.8 0.4 0.058 13.3 0.4 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_16 PF13191.6 RUS71454.1 - 0.068 13.5 0.1 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MCD_N PF17408.2 RUS71454.1 - 0.081 13.1 0.2 0.82 9.9 0.0 2.9 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Roc PF08477.13 RUS71454.1 - 0.092 13.0 0.0 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2110 PF09883.9 RUS71454.1 - 0.14 11.8 1.4 0.53 9.9 1.4 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) DCAF17 PF15802.5 RUS71455.1 - 0.016 13.9 3.1 0.098 11.3 3.1 1.9 1 1 0 1 1 1 0 DDB1- and CUL4-associated factor 17 DCAF17 PF15802.5 RUS71456.1 - 1.3e-27 96.6 0.1 1.5e-27 96.4 0.1 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 HECW_N PF16562.5 RUS71459.1 - 0.11 12.4 0.2 11 5.9 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF1272 PF06906.11 RUS71459.1 - 1.4 9.1 5.5 3.3 7.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) DDE_Tnp_IS1595 PF12762.7 RUS71460.1 - 7.3e-31 107.2 0.0 6.3e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 ISXO2-like transposase domain RNase_P_p30 PF01876.16 RUS71460.1 - 0.00011 21.7 0.1 0.35 10.3 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit p30 US10 PF17617.2 RUS71460.1 - 0.19 11.8 0.0 30 4.7 0.0 2.3 2 0 0 2 2 2 0 Viral unique short region 10 DUF1870 PF08965.10 RUS71461.1 - 0.02 14.9 0.1 0.084 12.9 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) Polyketide_cyc PF03364.20 RUS71463.1 - 4.3e-17 62.5 0.0 6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport BUD22 PF09073.10 RUS71464.1 - 0.28 10.5 8.0 0.36 10.1 8.0 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RUS71464.1 - 0.84 7.7 16.6 1.1 7.3 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 RUS71464.1 - 3.8 6.8 9.4 5.1 6.4 9.4 1.2 1 0 0 1 1 1 0 SDA1 7tm_1 PF00001.21 RUS71465.1 - 1.5e-53 181.8 20.3 8.7e-50 169.5 12.4 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS71465.1 - 5.6e-05 23.0 16.6 5.7e-05 23.0 13.8 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS71465.1 - 0.052 12.9 19.3 0.21 10.9 15.1 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS71465.1 - 0.16 11.3 24.4 0.47 9.7 0.8 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4179 PF13786.6 RUS71465.1 - 0.25 11.9 0.9 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF667 PF05018.13 RUS71467.1 - 1.1e-33 116.5 0.0 1.7e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF667) gerPA PF10676.9 RUS71467.1 - 3.4 8.0 5.2 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 Spore germination protein gerPA/gerPF Peptidase_M76 PF09768.9 RUS71468.1 - 3.9e-47 160.2 7.3 4.9e-47 159.9 7.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 RUS71468.1 - 0.0053 16.6 0.2 0.0078 16.1 0.2 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M13 PF01431.21 RUS71468.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M13 DUF4743 PF15916.5 RUS71469.1 - 1.4e-32 112.1 0.0 2.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 RUS71469.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain fn3 PF00041.21 RUS71470.1 - 2.7e-28 98.1 7.8 3.7e-10 40.0 0.2 5.5 5 1 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS71470.1 - 0.0019 18.8 7.3 0.044 14.4 0.1 3.9 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 RUS71470.1 - 0.005 16.7 2.8 0.37 10.6 0.0 4.1 4 1 0 4 4 4 1 Tissue factor Ig_3 PF13927.6 RUS71471.1 - 1.1e-59 198.9 4.4 6.7e-13 49.0 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 RUS71471.1 - 1.5e-48 162.8 0.0 3e-12 46.5 0.0 5.7 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS71471.1 - 3.1e-41 139.6 2.5 9.1e-08 32.3 0.0 5.6 4 1 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 RUS71471.1 - 6.7e-26 90.3 6.2 1.2e-07 31.8 0.0 6.3 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 RUS71471.1 - 4.6e-23 81.5 9.3 4.2e-05 23.7 0.0 7.2 6 4 1 7 7 7 5 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS71471.1 - 1.5e-08 34.6 0.3 0.076 13.1 0.0 4.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS71471.1 - 1.8e-06 27.4 0.1 2.4 7.8 0.0 5.1 5 1 0 5 5 5 2 Immunoglobulin domain Lectin_C PF00059.21 RUS71471.1 - 1.5e-05 25.7 0.0 4.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain Ig_C17orf99 PF17736.1 RUS71471.1 - 0.00055 19.9 0.1 3.1 7.9 0.0 5.0 5 2 0 5 5 5 1 C17orf99 Ig domain AIRS PF00586.24 RUS71472.1 - 8.7e-12 45.5 0.2 9.4e-12 45.4 0.2 1.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Peptidase_M48 PF01435.18 RUS71473.1 - 1.8e-24 86.6 0.1 4.2e-24 85.4 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M48 WD40 PF00400.32 RUS71474.1 - 1.2e-13 51.3 4.7 0.015 16.2 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71474.1 - 0.00012 22.3 0.1 0.26 11.6 0.0 3.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Stathmin PF00836.19 RUS71475.1 - 1.5e-39 135.1 53.9 4.7e-26 91.4 23.5 3.2 1 1 2 3 3 3 3 Stathmin family HMGL-like PF00682.19 RUS71475.1 - 0.25 10.9 6.6 0.34 10.4 6.6 1.2 1 0 0 1 1 1 0 HMGL-like MLTR_LBD PF17765.1 RUS71475.1 - 0.35 11.0 3.4 2.2 8.4 0.3 2.2 1 1 1 2 2 2 0 MmyB-like transcription regulator ligand binding domain FAD-SLDH PF12318.8 RUS71475.1 - 6.2 6.9 11.9 9.4 6.3 2.0 2.7 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ribonuc_2-5A PF06479.12 RUS71475.1 - 6.5 6.9 14.2 1.2 9.3 2.4 2.8 1 1 2 3 3 3 0 Ribonuclease 2-5A Fib_alpha PF08702.10 RUS71475.1 - 7.5 6.7 30.4 9.9 6.3 10.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tubulin PF00091.25 RUS71476.1 - 4.4e-68 229.4 0.0 5.8e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS71476.1 - 1.3e-51 174.0 0.0 2.1e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS71476.1 - 0.00037 20.2 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GKAP PF03359.13 RUS71477.1 - 8.6e-26 91.3 10.7 8.6e-26 91.3 10.7 5.1 2 2 1 5 5 5 1 Guanylate-kinase-associated protein (GKAP) protein Aldose_epim PF01263.20 RUS71478.1 - 5.4e-91 305.0 0.1 6.1e-91 304.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase LRR_6 PF13516.6 RUS71479.1 - 4.3e-07 29.5 1.5 0.14 12.3 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 RUS71479.1 - 0.016 15.7 9.0 0.21 12.1 3.9 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS71479.1 - 0.25 11.1 8.2 0.66 9.8 3.4 3.3 3 0 0 3 3 3 0 Leucine rich repeat XFP_C PF09363.10 RUS71480.1 - 0.081 12.4 0.1 0.26 10.7 0.1 1.8 1 1 0 1 1 1 0 XFP C-terminal domain dNK PF01712.19 RUS71481.1 - 2.8e-11 43.6 0.8 5e-11 42.9 0.8 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Herpes_ori_bp PF02399.15 RUS71482.1 - 6.9e-18 64.1 0.2 1.4e-17 63.1 0.2 1.4 1 0 0 1 1 1 1 Origin of replication binding protein AAA PF00004.29 RUS71482.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pack_N PF02500.15 RUS71487.1 - 2.2e-12 47.4 0.0 3.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus ResIII PF04851.15 RUS71487.1 - 0.034 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FhuF_C PF11575.8 RUS71489.1 - 0.025 14.5 0.5 0.054 13.4 0.5 1.6 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain Fumarate_red_C PF02300.17 RUS71491.1 - 0.032 14.3 1.0 0.067 13.3 1.0 1.5 1 0 0 1 1 1 0 Fumarate reductase subunit C LAP1C PF05609.12 RUS71491.1 - 1 8.4 12.3 1.5 7.8 12.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_B PF00136.21 RUS71492.1 - 1.5e-17 63.5 8.1 3e-17 62.5 8.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RUS71492.1 - 5.4e-08 32.4 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 RUS71492.1 - 5.2e-05 23.0 0.4 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Phage_T4_gp36 PF03903.13 RUS71492.1 - 0.033 14.2 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Phage T4 tail fibre NuiA PF07924.11 RUS71495.1 - 0.092 13.1 1.0 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Shisa PF13908.6 RUS71495.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator HPPK PF01288.20 RUS71497.1 - 0.068 13.7 0.1 0.24 11.9 0.1 1.9 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Endonuc_Holl PF10107.9 RUS71497.1 - 2.7 7.8 6.6 9.3 6.1 6.6 1.9 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CENP-H PF05837.12 RUS71497.1 - 4.8 7.6 12.1 2.9 8.3 8.5 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RRM_Rrp7 PF17799.1 RUS71499.1 - 0.029 14.2 0.2 0.044 13.6 0.2 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain LEP503 PF15221.6 RUS71503.1 - 6.6e-05 23.2 0.0 14 6.1 0.0 4.6 1 1 4 5 5 5 2 Lens epithelial cell protein LEP503 DUF3398 PF11878.8 RUS71503.1 - 0.0023 18.3 0.4 1.7 9.1 0.1 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3398) TonB_C PF03544.14 RUS71503.1 - 0.0061 17.0 0.0 3.5 8.1 0.0 3.1 1 1 3 4 4 4 1 Gram-negative bacterial TonB protein C-terminal DUF3409 PF11889.8 RUS71503.1 - 0.011 15.6 9.1 4.3 7.3 0.1 4.4 2 1 3 5 5 5 0 Domain of unknown function (DUF3409) Antimicrobial_7 PF08102.11 RUS71503.1 - 0.012 15.8 0.0 59 4.0 0.0 3.8 1 1 3 4 4 4 0 Scorpion antimicrobial peptide DUF2795 PF11387.8 RUS71503.1 - 0.87 9.8 4.4 1.3e+02 2.8 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) DUF1181 PF06680.11 RUS71504.1 - 3.2e-11 43.1 30.8 32 4.4 0.0 14.9 1 1 16 17 17 17 13 Protein of unknown function (DUF1181) DUF4861 PF16153.5 RUS71504.1 - 3.7e-09 36.0 5.7 2.5 7.0 0.2 7.6 1 1 5 6 6 6 6 Domain of unknown function (DUF4861) ATPgrasp_Ter PF15632.6 RUS71505.1 - 8.3e-06 25.6 1.3 13 5.6 0.0 5.0 1 1 4 5 5 5 5 ATP-grasp in the biosynthetic pathway with Ter operon Exo_endo_phos PF03372.23 RUS71506.1 - 8e-18 64.8 0.0 1.5e-17 63.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CENP-B_dimeris PF09026.10 RUS71507.1 - 0.00031 21.1 12.7 0.00061 20.1 12.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Neur_chan_memb PF02932.16 RUS71507.1 - 0.0019 18.3 3.4 0.055 13.5 0.2 2.1 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.11 RUS71507.1 - 0.0063 15.1 3.5 0.012 14.1 3.1 1.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Orf78 PF06024.12 RUS71507.1 - 0.011 16.0 0.1 0.054 13.8 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) GCIP PF13324.6 RUS71507.1 - 0.019 14.6 3.1 0.027 14.1 3.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2722 PF10846.8 RUS71507.1 - 0.02 13.8 0.4 0.021 13.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2796 PF10986.8 RUS71507.1 - 0.049 13.6 0.2 0.076 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF3295 PF11702.8 RUS71507.1 - 0.072 12.4 3.6 0.091 12.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF3149 PF11346.8 RUS71507.1 - 0.11 12.1 2.0 0.6 9.8 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TFB6 PF17110.5 RUS71507.1 - 0.25 11.1 3.0 0.45 10.2 3.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 RUS71507.1 - 0.39 10.7 8.4 0.65 10.0 8.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RUS71507.1 - 0.51 9.6 23.2 0.72 9.1 23.2 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RUS71507.1 - 0.59 10.0 9.5 0.89 9.4 9.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RUS71507.1 - 1 7.5 11.3 1.4 7.1 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 RUS71507.1 - 2.5 7.1 29.4 1.8 7.6 26.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 RUS71507.1 - 2.7 7.3 11.6 3.8 6.8 11.6 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 RUS71507.1 - 3.1 8.1 12.0 6.6 7.0 12.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FRQ PF09421.10 RUS71507.1 - 5.2 5.0 8.2 7 4.5 8.2 1.1 1 0 0 1 1 1 0 Frequency clock protein RVT_1 PF00078.27 RUS71508.1 - 7.9e-26 90.9 0.0 9.2e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_35 PF01301.19 RUS71509.1 - 1.5e-96 323.7 0.0 2.1e-96 323.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 RUS71509.1 - 7e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 RUS71509.1 - 0.0014 19.1 0.7 0.013 16.0 0.0 2.6 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Bactofilin PF04519.13 RUS71509.1 - 0.17 12.2 0.4 0.42 10.9 0.4 1.6 1 0 0 1 1 1 0 Polymer-forming cytoskeletal TPR_11 PF13414.6 RUS71510.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Prok-RING_1 PF14446.6 RUS71510.1 - 0.23 11.4 5.5 0.3 11.0 0.2 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Phage_BR0599 PF09356.10 RUS71510.1 - 1.2 9.5 13.4 6.7 7.1 0.1 5.2 6 0 0 6 6 6 0 Phage conserved hypothetical protein BR0599 PT PF04886.12 RUS71511.1 - 0.00027 20.4 153.1 1.8e+04 -28.2 53.8 9.9 1 1 1 2 2 2 0 PT repeat Helicase_PWI PF18149.1 RUS71512.1 - 0.015 15.5 0.5 0.027 14.6 0.3 1.6 1 1 0 1 1 1 0 N-terminal helicase PWI domain DUF4427 PF14468.6 RUS71512.1 - 0.024 14.7 0.4 0.04 14.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) PFK PF00365.20 RUS71512.1 - 0.16 11.3 3.2 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Phosphofructokinase ALS2CR8 PF15299.6 RUS71512.1 - 0.19 11.6 2.7 0.28 11.1 2.7 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DDE_Tnp_4 PF13359.6 RUS71513.1 - 4.8e-16 58.8 0.0 8.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos_2 PF14529.6 RUS71513.1 - 4.9e-08 32.8 1.0 1.2e-07 31.6 0.1 2.2 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase DDE_Tnp_1_7 PF13843.6 RUS71513.1 - 7.1e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Transposase IS4 HEM4 PF02602.15 RUS71514.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD HBS1_N PF08938.10 RUS71515.1 - 1.3 9.4 7.7 0.22 11.8 1.7 2.5 2 1 0 2 2 2 0 HBS1 N-terminus Ribosomal_L37e PF01907.19 RUS71516.1 - 0.0034 17.5 0.4 0.0034 17.5 0.4 1.6 1 1 0 1 1 1 1 Ribosomal protein L37e PHD PF00628.29 RUS71516.1 - 0.055 13.4 10.3 0.26 11.2 10.0 2.1 1 1 1 2 2 2 0 PHD-finger ABG_transport PF03806.13 RUS71517.1 - 0.014 13.6 5.9 0.36 9.0 1.1 2.6 1 1 1 2 2 2 0 AbgT putative transporter family DCAF15_WD40 PF14939.6 RUS71517.1 - 0.17 11.5 0.1 5.9 6.5 0.1 2.0 1 1 1 2 2 2 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF1375 PF07119.12 RUS71517.1 - 1.5 9.3 11.1 1.3e+02 3.1 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1375) Frag1 PF10277.9 RUS71518.1 - 2.2e-08 33.9 1.1 2.5e-08 33.7 1.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7tm_1 PF00001.21 RUS71519.1 - 5.8e-15 55.3 0.0 9.2e-13 48.1 0.0 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Tim17 PF02466.19 RUS71520.1 - 3.3e-10 40.3 0.1 5.8e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acyl_transf_3 PF01757.22 RUS71521.1 - 1.3e-27 96.8 38.0 1.3e-27 96.8 38.0 1.7 2 0 0 2 2 2 1 Acyltransferase family Tmemb_170 PF10190.9 RUS71521.1 - 0.033 14.6 1.3 0.033 14.6 1.3 4.3 5 1 0 5 5 5 0 Putative transmembrane protein 170 Fz PF01392.22 RUS71522.1 - 5.5e-27 94.6 2.9 1e-26 93.8 2.9 1.4 1 0 0 1 1 1 1 Fz domain NTR PF01759.21 RUS71522.1 - 1e-06 28.5 0.3 2e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 RUS71522.1 - 0.00017 21.5 0.5 0.00031 20.6 0.5 1.4 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase DUF4698 PF15769.5 RUS71523.1 - 1.5e-05 24.2 0.1 1.5e-05 24.2 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4698) SOGA PF11365.8 RUS71523.1 - 1.5 10.0 5.9 10 7.3 0.5 2.3 2 0 0 2 2 2 0 Protein SOGA HtrL_YibB PF09612.10 RUS71524.1 - 0.00036 20.1 0.0 0.00044 19.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DUF2798 PF11391.8 RUS71525.1 - 0.00061 19.8 30.4 0.62 10.2 11.9 3.6 1 1 2 3 3 3 3 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RUS71525.1 - 0.0063 16.5 14.9 0.39 10.7 6.5 3.7 1 1 1 2 2 2 2 Glycine zipper DUF5455 PF17537.2 RUS71525.1 - 0.85 10.1 18.4 12 6.4 0.5 4.6 1 1 2 3 3 3 0 Family of unknown function (DUF5455) Gly-zipper_YMGG PF13441.6 RUS71525.1 - 1.8 8.4 7.4 2.2 8.1 0.3 3.3 2 2 1 3 3 3 0 YMGG-like Gly-zipper SecE PF00584.20 RUS71525.1 - 8.2 6.4 32.2 1.4 8.9 2.1 4.2 1 1 3 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex Syndecan PF01034.20 RUS71527.1 - 1.5e-28 98.5 0.1 9.3e-28 95.9 0.0 2.2 2 0 0 2 2 2 1 Syndecan domain Thyroglobulin_1 PF00086.18 RUS71527.1 - 9.2e-21 73.3 9.0 6.3e-12 45.0 0.9 2.3 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat FeoB_associated PF12669.7 RUS71527.1 - 0.081 13.3 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Glycophorin_A PF01102.18 RUS71527.1 - 0.1 12.8 2.5 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 Glycophorin A Serglycin PF04360.12 RUS71527.1 - 0.89 9.5 4.5 0.49 10.3 0.8 2.1 2 0 0 2 2 2 0 Serglycin GAGA_bind PF06217.12 RUS71528.1 - 0.004 17.5 14.4 0.0049 17.2 14.4 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family Connexin PF00029.19 RUS71528.1 - 0.0062 16.3 8.4 0.0076 16.0 8.4 1.2 1 0 0 1 1 1 1 Connexin RNA_pol_Rpc4 PF05132.14 RUS71528.1 - 0.0074 16.7 12.8 0.011 16.1 12.8 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 SR-25 PF10500.9 RUS71528.1 - 0.019 14.6 45.2 0.035 13.7 45.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PcfK PF14058.6 RUS71528.1 - 0.019 15.2 17.8 0.028 14.7 17.8 1.3 1 0 0 1 1 1 0 PcfK-like protein DUF3464 PF11947.8 RUS71528.1 - 0.036 13.8 13.5 0.07 12.9 13.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PPL5 PF18168.1 RUS71528.1 - 0.038 13.3 10.0 0.045 13.0 10.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Eapp_C PF10238.9 RUS71528.1 - 0.097 12.7 8.9 0.17 12.0 8.9 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF5308 PF17233.2 RUS71528.1 - 0.11 12.7 2.3 0.2 11.9 2.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RP-C_C PF11800.8 RUS71528.1 - 0.13 12.3 5.2 0.2 11.7 5.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.17 RUS71528.1 - 0.14 12.3 9.4 0.18 12.0 9.4 1.1 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.8 RUS71528.1 - 0.17 10.7 21.5 0.21 10.5 21.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rxt3 PF08642.10 RUS71528.1 - 0.18 12.6 4.9 0.33 11.7 4.9 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 CDC45 PF02724.14 RUS71528.1 - 0.28 9.4 11.5 0.33 9.2 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.10 RUS71528.1 - 0.29 12.1 22.6 0.72 10.8 22.6 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Jak1_Phl PF17887.1 RUS71528.1 - 0.31 11.0 14.2 0.53 10.3 14.2 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF2052 PF09747.9 RUS71528.1 - 0.4 10.8 11.6 0.56 10.3 11.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4337 PF14235.6 RUS71528.1 - 0.45 10.6 8.3 0.66 10.1 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Coilin_N PF15862.5 RUS71528.1 - 0.48 10.2 24.5 0.88 9.4 24.5 1.6 1 0 0 1 1 1 0 Coilin N-terminus EIIBC-GUT_N PF03612.14 RUS71528.1 - 0.54 10.0 9.4 0.9 9.2 9.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Paramyxo_ncap PF00973.19 RUS71528.1 - 0.55 9.1 6.7 0.68 8.8 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Zip PF02535.22 RUS71528.1 - 0.58 9.3 6.1 0.7 9.1 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RPN2_C PF18004.1 RUS71528.1 - 0.59 10.0 24.9 0.8 9.6 24.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sec62 PF03839.16 RUS71528.1 - 0.65 9.5 16.9 1.1 8.7 16.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 RUS71528.1 - 0.81 8.4 10.7 0.91 8.2 10.7 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 RUS71528.1 - 0.88 8.9 23.1 1.4 8.2 23.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger AAA_11 PF13086.6 RUS71528.1 - 0.98 9.2 14.0 1.3 8.8 14.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1168 PF06658.12 RUS71528.1 - 1.1 9.1 34.6 1.8 8.4 34.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SOBP PF15279.6 RUS71528.1 - 1.1 9.8 9.2 1.3 9.6 9.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF913 PF06025.12 RUS71528.1 - 1.3 8.0 5.3 1.4 7.8 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SRP-alpha_N PF04086.13 RUS71528.1 - 1.3 8.9 24.5 1.6 8.6 24.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CLN3 PF02487.17 RUS71528.1 - 1.4 7.9 4.5 1.7 7.6 4.5 1.3 1 0 0 1 1 1 0 CLN3 protein Afi1 PF07792.12 RUS71528.1 - 1.5 9.3 10.0 2.7 8.5 10.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.19 RUS71528.1 - 1.6 6.6 9.1 1.8 6.4 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ureide_permease PF07168.11 RUS71528.1 - 1.6 7.4 7.2 2.1 7.0 7.2 1.1 1 0 0 1 1 1 0 Ureide permease ALMT PF11744.8 RUS71528.1 - 2 7.2 11.2 2.2 7.0 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RabGAP-TBC PF00566.18 RUS71528.1 - 2 8.0 6.7 2.9 7.5 6.7 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Folate_carrier PF01770.18 RUS71528.1 - 2.5 6.7 7.1 4.7 5.8 7.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 RUS71528.1 - 3.2 7.5 20.3 4.4 7.1 20.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SspB PF04386.13 RUS71528.1 - 3.5 7.5 8.0 5.2 6.9 8.0 1.3 1 0 0 1 1 1 0 Stringent starvation protein B eIF3_subunit PF08597.10 RUS71528.1 - 3.6 7.4 32.8 5.4 6.8 32.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TMEM214 PF10151.9 RUS71528.1 - 3.7 5.9 19.4 4.3 5.7 19.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator FAM176 PF14851.6 RUS71528.1 - 3.8 7.2 6.1 7.6 6.2 6.1 1.6 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.6 RUS71528.1 - 3.9 7.6 17.4 5.9 7.1 17.4 1.4 1 0 0 1 1 1 0 YqfQ-like protein Serinc PF03348.15 RUS71528.1 - 3.9 6.3 5.1 5 5.9 5.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.20 RUS71528.1 - 4.2 5.5 8.8 5.3 5.2 8.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.6 RUS71528.1 - 4.5 7.6 10.9 6.9 7.0 10.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YL1 PF05764.13 RUS71528.1 - 5 7.2 29.4 8.2 6.5 29.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Importin_rep_4 PF18808.1 RUS71531.1 - 1.5e-31 108.5 3.1 2e-29 101.7 0.3 3.0 3 0 0 3 3 3 2 Importin repeat HEAT_2 PF13646.6 RUS71531.1 - 1.9e-05 25.0 0.1 0.082 13.3 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats IBN_N PF03810.19 RUS71531.1 - 9.3e-05 22.3 0.3 0.032 14.1 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Sec7_N PF12783.7 RUS71531.1 - 0.00054 19.9 3.6 0.12 12.2 1.4 3.7 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Xpo1 PF08389.12 RUS71531.1 - 0.0014 18.8 2.6 0.79 9.8 0.0 3.3 2 1 0 2 2 2 2 Exportin 1-like protein Arm_2 PF04826.13 RUS71531.1 - 0.011 15.2 1.0 0.018 14.5 1.0 1.4 1 0 0 1 1 1 0 Armadillo-like HEAT_EZ PF13513.6 RUS71531.1 - 4.7 7.8 10.6 5.3 7.7 0.1 5.3 5 2 1 6 6 6 0 HEAT-like repeat WD40 PF00400.32 RUS71532.1 - 1.9e-52 174.0 29.3 8.6e-11 42.2 0.3 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71532.1 - 3e-33 114.0 3.2 2.6e-09 37.3 0.0 6.7 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS71532.1 - 1.7e-11 44.4 1.7 0.0036 17.2 0.2 3.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RUS71532.1 - 3e-05 23.1 2.4 0.23 10.4 0.0 3.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RUS71532.1 - 0.00051 19.5 0.0 0.83 8.9 0.0 3.8 2 1 2 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 RUS71532.1 - 0.0063 15.3 0.1 0.7 8.6 0.0 3.0 2 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 RUS71532.1 - 0.0071 15.0 9.9 2.5 6.7 0.0 5.3 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 RUS71532.1 - 0.008 15.3 0.0 2.9 6.8 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 RUS71532.1 - 0.027 14.4 0.0 0.41 10.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 RUS71532.1 - 0.32 8.9 1.8 5.2 4.9 0.3 2.4 2 1 1 3 3 3 0 IKI3 family zf-C3HC4_3 PF13920.6 RUS71534.1 - 0.037 13.9 6.3 5.3 7.0 0.2 3.0 1 1 3 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RUN PF02759.19 RUS71535.1 - 3.8e-06 26.9 0.0 7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RUN domain Cyclin_N PF00134.23 RUS71536.1 - 5.1e-40 136.1 0.9 9.9e-37 125.5 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS71536.1 - 6e-28 97.3 0.2 3.2e-27 95.0 0.2 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain PLU-1 PF08429.11 RUS71537.1 - 0.0014 17.9 1.6 0.0017 17.6 1.6 1.2 1 0 0 1 1 1 1 PLU-1-like protein UPF0242 PF06785.11 RUS71537.1 - 0.019 15.1 7.7 0.036 14.2 7.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 RUS71537.1 - 0.92 9.6 7.4 0.11 12.6 2.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation zf-C3HC4_3 PF13920.6 RUS71538.1 - 4.2e-08 32.9 9.1 6.3e-08 32.4 9.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS71538.1 - 3.6e-07 29.9 10.9 6.3e-07 29.2 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS71538.1 - 7.7e-07 29.0 11.3 5.3e-06 26.3 11.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS71538.1 - 7.6e-06 25.7 10.7 1.4e-05 24.8 10.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS71538.1 - 1e-05 25.3 6.2 1.7e-05 24.6 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS71538.1 - 3e-05 24.0 6.2 5.5e-05 23.1 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS71538.1 - 4.6e-05 23.6 7.1 8.6e-05 22.7 7.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RUS71538.1 - 0.00034 20.9 11.8 0.0015 18.8 12.0 1.9 1 1 1 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 RUS71538.1 - 0.00047 20.1 2.4 0.00073 19.5 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TBCC_N PF16752.5 RUS71538.1 - 0.005 17.3 3.4 0.0084 16.5 3.4 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain zinc_ribbon_15 PF17032.5 RUS71538.1 - 0.028 15.2 4.8 0.063 14.0 4.8 1.6 1 0 0 1 1 1 0 zinc-ribbon family Zn_ribbon_17 PF17120.5 RUS71538.1 - 0.032 13.8 4.6 0.05 13.2 4.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RUS71538.1 - 0.056 13.6 9.0 0.21 11.8 9.0 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RUS71538.1 - 0.082 12.7 11.9 0.14 12.0 5.7 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain cobW PF02492.19 RUS71538.1 - 0.12 11.9 1.1 0.22 11.1 1.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rubredoxin PF00301.20 RUS71538.1 - 0.13 12.4 2.6 1.4 9.0 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_9 PF14369.6 RUS71538.1 - 0.22 11.8 5.4 4.9 7.5 2.6 2.6 2 1 0 2 2 2 0 zinc-ribbon MnmE_helical PF12631.7 RUS71538.1 - 0.32 11.2 2.2 0.38 10.9 2.2 1.1 1 0 0 1 1 1 0 MnmE helical domain DivIC PF04977.15 RUS71538.1 - 2.7 7.8 8.0 2.4 8.0 2.0 1.7 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L37e PF01907.19 RUS71538.1 - 2.7 8.2 8.5 0.75 10.0 3.4 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e zf-ribbon_3 PF13248.6 RUS71538.1 - 2.9 7.4 9.1 3.8 7.0 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 RUS71538.1 - 6.5 6.9 10.2 36 4.5 0.8 2.0 1 1 1 2 2 2 0 Double zinc ribbon PKcGMP_CC PF16808.5 RUS71538.1 - 7.7 6.5 9.4 1.6 8.7 0.2 3.6 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IBR PF01485.21 RUS71538.1 - 8.4 6.7 12.9 6.9e+02 0.6 12.9 3.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain GAS PF13851.6 RUS71539.1 - 0.0045 16.4 16.1 0.0045 16.4 16.1 2.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 RUS71539.1 - 0.35 11.2 10.8 0.5 10.7 3.2 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HisKA PF00512.25 RUS71539.1 - 2.6 8.2 5.5 2.2 8.4 0.0 2.8 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Spc7 PF08317.11 RUS71539.1 - 9.1 5.1 24.9 17 4.2 16.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 RUS71540.1 - 0.57 10.4 41.8 1.3 9.2 5.7 4.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 RUS71540.1 - 2.1 8.7 31.2 0.64 10.3 0.3 4.7 4 0 0 4 4 4 0 Uncharacterized conserved protein Spc7 PF08317.11 RUS71540.1 - 3.1 6.6 67.6 0.13 11.2 17.3 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 RUS71540.1 - 8.1 6.8 59.1 3.5 8.1 1.3 3.9 1 1 2 3 3 3 0 Fez1 zf-B_box PF00643.24 RUS71541.1 - 3.9e-09 36.5 7.1 3.9e-09 36.5 7.1 3.6 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 RUS71541.1 - 1.5e-07 31.6 0.0 1.5e-07 31.6 0.0 2.7 3 0 0 3 3 3 1 MATH domain zf-C3HC4_3 PF13920.6 RUS71541.1 - 0.00049 19.9 16.2 0.00049 19.9 16.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_3 PF14606.6 RUS71541.1 - 0.089 12.9 0.7 0.27 11.4 0.7 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_Treg PF04761.12 RUS71542.1 - 0.081 13.0 0.0 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator PP2C PF00481.21 RUS71543.1 - 9e-62 209.0 0.0 1.4e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS71543.1 - 0.00021 21.0 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C CPBP PF02517.16 RUS71545.1 - 2.2e-17 63.2 4.4 2.2e-17 63.2 4.4 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Hemocyanin_N PF03722.14 RUS71545.1 - 0.015 15.8 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain HSP70 PF00012.20 RUS71546.1 - 3.9e-260 864.2 1.2 4.4e-260 864.0 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS71546.1 - 1.2e-17 63.7 0.0 6.1e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 RUS71546.1 - 0.00019 21.2 0.0 0.0011 18.8 0.0 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 RUS71546.1 - 0.01 16.3 1.2 7.4 7.0 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 RUS71546.1 - 0.028 13.7 0.6 0.22 10.8 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Tubulin PF00091.25 RUS71547.1 - 2.6e-68 230.1 0.0 3.5e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS71547.1 - 6.1e-52 175.1 0.0 9.5e-52 174.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS71547.1 - 0.00049 19.8 0.0 0.00096 18.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF4200 PF13863.6 RUS71549.1 - 8.7e-27 93.9 41.0 1.8e-26 92.9 26.5 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) Mod_r PF07200.13 RUS71549.1 - 7.2e-05 22.9 30.2 0.017 15.3 3.5 4.2 1 1 3 4 4 4 3 Modifier of rudimentary (Mod(r)) protein Prefoldin_2 PF01920.20 RUS71549.1 - 0.011 15.7 5.4 0.011 15.7 5.4 4.3 2 2 1 3 3 3 0 Prefoldin subunit APG6_N PF17675.1 RUS71549.1 - 0.013 16.1 9.8 0.013 16.1 9.8 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 RUS71549.1 - 0.086 11.9 20.4 0.024 13.7 9.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HalX PF08663.10 RUS71549.1 - 0.61 10.5 6.2 0.5 10.7 3.1 2.5 2 0 0 2 2 2 0 HalX domain DUF1664 PF07889.12 RUS71549.1 - 1.2 9.2 19.3 4.4 7.4 3.5 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 RUS71549.1 - 1.7 9.1 18.7 0.67 10.4 0.9 5.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 RUS71549.1 - 3.2 6.9 21.4 1.5 8.0 2.4 2.3 2 0 0 2 2 2 0 TMPIT-like protein MIP-T3_C PF17749.1 RUS71549.1 - 6.9 6.6 22.6 9.1 6.2 7.2 2.7 1 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 RUS71549.1 - 10 4.9 35.2 2 7.2 10.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Lectin_C PF00059.21 RUS71551.1 - 4.1e-14 53.2 0.1 1.1e-13 51.8 0.0 1.8 1 1 1 2 2 2 1 Lectin C-type domain Reprolysin PF01421.19 RUS71552.1 - 2.4e-12 47.2 0.1 1.1e-11 45.1 0.1 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS71552.1 - 2.5e-10 40.9 0.0 4.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS71552.1 - 2.5e-07 30.8 0.1 4.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 RUS71552.1 - 2.2e-06 28.1 0.1 4.9e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_4 PF13583.6 RUS71552.1 - 8.3e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS71552.1 - 3.6e-05 24.3 0.4 8.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 RUS71552.1 - 0.049 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 RUS71552.1 - 0.085 12.7 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin MENTAL PF10457.9 RUS71554.1 - 1.8e-28 99.6 0.0 2.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 RUS71554.1 - 1.3e-25 90.0 0.0 1.6e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 START domain Octapeptide PF03373.14 RUS71555.1 - 4.3 8.1 19.8 1e+03 1.0 0.0 10.2 9 0 0 9 9 9 0 Octapeptide repeat GAF PF01590.26 RUS71556.1 - 1.5e-11 45.0 0.0 2.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 RUS71556.1 - 1.9e-05 24.9 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 GAF domain bHLH-MYC_N PF14215.6 RUS71556.1 - 0.041 14.2 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal UPF0113_N PF17833.1 RUS71557.1 - 5.5e-31 107.0 0.3 8.1e-31 106.4 0.3 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 RUS71557.1 - 3.7e-23 81.6 0.0 6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain TatD_DNase PF01026.21 RUS71558.1 - 2.5e-17 63.1 0.0 3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DDE_Tnp_IS1595 PF12762.7 RUS71559.1 - 1.8e-09 37.8 0.1 1.1e-08 35.2 0.0 2.3 2 1 0 2 2 2 1 ISXO2-like transposase domain Dimer_Tnp_hAT PF05699.14 RUS71559.1 - 0.025 14.3 0.4 0.055 13.3 0.4 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF3918 PF13056.6 RUS71560.1 - 0.004 16.7 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3918) Cbl_N PF02262.16 RUS71560.1 - 0.051 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DTHCT PF08070.11 RUS71561.1 - 0.55 11.0 5.6 0.93 10.3 3.2 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region Arc_C PF18162.1 RUS71562.1 - 0.018 14.9 0.1 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Arc C-lobe DUF4917 PF16263.5 RUS71562.1 - 0.087 12.1 0.0 0.19 11.1 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4917) Nif11 PF07862.11 RUS71562.1 - 0.26 11.6 1.3 58 4.1 0.0 3.6 3 1 1 4 4 4 0 Nif11 domain Fungal_trans_2 PF11951.8 RUS71563.1 - 0.0018 17.2 0.4 0.92 8.2 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Vault PF01505.18 RUS71563.1 - 0.005 17.0 2.3 12 6.1 0.1 4.2 4 0 0 4 4 4 1 Major Vault Protein repeat domain DUF3572 PF12096.8 RUS71563.1 - 0.081 13.1 0.0 23 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) DUF3128 PF11326.8 RUS71563.1 - 0.22 11.9 5.1 15 6.0 0.8 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) ATG16 PF08614.11 RUS71564.1 - 0.00017 21.9 11.2 0.00034 20.9 11.2 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 RUS71564.1 - 0.062 12.2 17.5 0.094 11.6 17.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LigD_N PF13298.6 RUS71564.1 - 0.067 13.5 0.5 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) CEP209_CC5 PF16574.5 RUS71564.1 - 0.088 13.0 18.0 0.59 10.3 9.6 2.9 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 CENP-F_leu_zip PF10473.9 RUS71564.1 - 0.14 12.2 25.7 0.045 13.8 16.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 RUS71564.1 - 0.14 12.0 23.2 0.17 11.7 6.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4032 PF13224.6 RUS71564.1 - 0.24 11.3 6.4 0.7 9.7 5.7 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4032) PRK PF00485.18 RUS71564.1 - 0.28 10.9 2.2 0.47 10.2 2.2 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Exonuc_VII_L PF02601.15 RUS71564.1 - 1 8.9 7.2 1.6 8.2 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SCAB_CC PF16712.5 RUS71564.1 - 1.3 8.9 14.3 2 8.2 14.3 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein KLRAQ PF10205.9 RUS71564.1 - 1.9 8.8 17.4 6 7.2 1.6 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 RUS71564.1 - 3.4 8.0 7.3 0.31 11.3 1.1 2.5 2 1 1 3 3 3 0 Haemolysin XhlA Cadherin PF00028.17 RUS71565.1 - 7.3e-193 625.7 35.1 1.4e-17 63.9 0.1 20.3 19 1 1 20 20 20 19 Cadherin domain Cadherin_2 PF08266.12 RUS71565.1 - 1.2e-18 66.7 0.0 0.29 11.0 0.0 9.8 8 1 0 8 8 8 5 Cadherin-like RET_CLD1 PF17756.1 RUS71565.1 - 1.3e-07 31.9 0.2 3.6 7.9 0.0 6.4 6 0 0 6 6 5 1 RET Cadherin like domain 1 DUF3899 PF13038.6 RUS71565.1 - 4.6e-05 23.8 0.3 0.44 11.1 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3899) MAP17 PF15807.5 RUS71565.1 - 5.1e-05 23.5 4.6 0.015 15.5 0.2 2.4 1 1 0 2 2 2 2 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DAG1 PF05454.11 RUS71565.1 - 0.0014 18.1 5.6 0.19 11.1 1.0 2.5 1 1 1 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) Cadherin_C_2 PF16492.5 RUS71565.1 - 0.0027 18.4 6.1 1.1 10.1 0.6 3.2 1 1 1 2 2 2 2 Cadherin cytoplasmic C-terminal Trp_oprn_chp PF09534.10 RUS71565.1 - 0.0033 17.2 2.6 0.0069 16.2 2.6 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2207 PF09972.9 RUS71565.1 - 0.0077 15.0 0.2 0.018 13.8 0.2 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 RUS71565.1 - 0.0086 16.9 3.4 2 9.4 0.2 2.6 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RUS71565.1 - 0.025 14.5 7.1 0.58 10.1 1.3 3.0 1 1 1 2 2 2 0 TMEM154 protein family GPDPase_memb PF10110.9 RUS71565.1 - 0.042 12.6 0.9 5.2 5.8 0.0 2.1 1 1 1 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase TssO PF17561.2 RUS71565.1 - 0.043 13.9 0.2 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO Glycophorin_A PF01102.18 RUS71565.1 - 0.054 13.7 8.9 0.24 11.6 1.0 3.0 1 1 1 2 2 2 0 Glycophorin A ChitinaseA_N PF08329.10 RUS71565.1 - 0.062 13.0 0.0 34 4.1 0.0 3.9 4 0 0 4 4 4 0 Chitinase A, N-terminal domain Y_Y_Y PF07495.13 RUS71565.1 - 0.071 13.1 0.2 4.6 7.3 0.0 4.0 5 0 0 5 5 4 0 Y_Y_Y domain DUF4064 PF13273.6 RUS71565.1 - 0.13 12.5 3.1 0.38 11.1 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3377 PF11857.8 RUS71565.1 - 0.87 9.6 4.5 11 6.1 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Orf78 PF06024.12 RUS71565.1 - 0.96 9.8 7.0 5.6 7.3 0.5 2.7 1 1 1 2 2 2 0 Orf78 (ac78) DUF4577 PF15145.6 RUS71565.1 - 1 9.4 5.6 12 6.0 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) SIT PF15330.6 RUS71565.1 - 1.2 9.6 2.7 15 6.1 0.1 2.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Amnionless PF14828.6 RUS71565.1 - 1.3 7.7 7.1 5.4 5.7 2.1 2.5 1 1 1 2 2 2 0 Amnionless Tetraspanin PF00335.20 RUS71565.1 - 2.1 8.0 13.1 7.1 6.3 2.9 2.1 1 1 1 2 2 2 0 Tetraspanin family SGP PF17228.2 RUS71565.1 - 6.1 7.8 6.1 2.3e+02 2.7 7.2 2.5 2 0 0 2 2 2 0 Sulphur globule protein DCAF17 PF15802.5 RUS71566.1 - 1.8e-24 86.3 0.6 2e-24 86.1 0.6 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 HTH_5 PF01022.20 RUS71566.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Phostensin_N PF13916.6 RUS71567.1 - 0.23 11.8 4.0 19 5.7 0.2 3.4 2 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Branch PF02485.21 RUS71568.1 - 7.1e-29 101.0 0.0 6.1e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Core-2/I-Branching enzyme 7tm_1 PF00001.21 RUS71570.1 - 6.9e-08 32.1 14.8 8.6e-08 31.8 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) A_deaminase PF00962.22 RUS71571.1 - 1.6e-24 86.9 0.0 2.9e-24 86.0 0.0 1.4 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 RUS71571.1 - 1.1e-16 60.9 0.2 6e-16 58.5 0.1 2.2 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal A_deaminase PF00962.22 RUS71572.1 - 5.2e-24 85.2 0.0 6.7e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 RUS71572.1 - 0.001 19.3 0.3 0.0084 16.4 0.1 2.5 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal zf-C2H2 PF00096.26 RUS71573.1 - 1.8e-31 106.8 79.2 2.7e-05 24.4 3.1 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS71573.1 - 2.4e-26 90.9 70.3 4.8e-06 26.7 0.3 10.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS71573.1 - 6.1e-26 88.9 74.1 0.0041 17.8 2.7 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS71573.1 - 3.7e-14 52.6 40.9 0.083 13.2 0.6 9.4 9 0 0 9 9 9 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS71573.1 - 3.9e-14 52.2 55.3 0.0068 16.4 0.2 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 RUS71573.1 - 2.4e-12 46.8 56.1 0.13 12.7 0.8 9.5 9 0 0 9 9 9 7 Zinc-finger of C2H2 type BolA PF01722.18 RUS71573.1 - 0.027 14.8 12.1 0.79 10.0 1.2 5.0 3 2 1 4 4 4 0 BolA-like protein RNA_pol_Rpb1_4 PF05000.17 RUS71573.1 - 0.029 14.3 0.1 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 Zn-ribbon_8 PF09723.10 RUS71573.1 - 0.29 11.3 30.9 0.84 9.8 0.6 6.7 3 2 4 7 7 7 0 Zinc ribbon domain zf-MYST PF17772.1 RUS71573.1 - 0.9 9.2 22.4 4.4 7.0 0.1 7.0 6 3 2 8 8 8 0 MYST family zinc finger domain zf-Di19 PF05605.12 RUS71573.1 - 0.92 9.9 53.0 3.3 8.1 6.5 5.9 4 2 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS71573.1 - 1 10.0 40.8 2 9.1 0.3 6.3 3 2 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats Cript PF10235.9 RUS71573.1 - 2 9.1 35.5 1.1 9.8 1.1 6.7 1 1 5 6 6 6 0 Microtubule-associated protein CRIPT SH2 PF00017.24 RUS71574.1 - 1.5e-14 53.8 0.0 3.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 RUS71574.1 - 0.17 11.8 0.0 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain DUF2781 PF10914.8 RUS71576.1 - 5.9e-13 49.5 3.8 5.9e-13 49.5 3.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2781) ApoLp-III PF07464.11 RUS71577.1 - 0.018 15.1 1.9 0.65 10.1 0.6 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 RUS71578.1 - 0.041 13.8 0.5 0.062 13.2 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5559 PF17714.1 RUS71578.1 - 0.042 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5559) Fibrinogen_C PF00147.18 RUS71578.1 - 0.052 13.4 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Dynamitin PF04912.14 RUS71578.1 - 0.069 12.5 0.1 0.12 11.7 0.1 1.3 1 1 0 1 1 1 0 Dynamitin HSBP1 PF06825.12 RUS71578.1 - 0.12 12.3 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 CENP-F_N PF10481.9 RUS71578.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain adh_short PF00106.25 RUS71580.1 - 1.5e-32 112.6 0.3 2e-32 112.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS71580.1 - 6.1e-21 75.1 0.1 7.5e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Somatomedin_B PF01033.17 RUS71582.1 - 0.037 14.4 14.6 0.037 14.4 14.6 2.0 2 0 0 2 2 2 0 Somatomedin B domain DUF2345 PF10106.9 RUS71583.1 - 0.00021 21.2 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) IncF PF17626.2 RUS71583.1 - 0.0018 18.6 8.8 7.5 7.0 0.2 5.3 1 1 4 5 5 5 3 Inclusion membrane protein F Gly_transf_sug PF04488.15 RUS71583.1 - 0.071 13.7 3.2 23 5.7 0.1 3.6 1 1 1 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif Putative_PNPOx PF01243.20 RUS71583.1 - 0.49 10.6 15.4 50 4.2 0.2 6.5 3 2 2 6 6 6 0 Pyridoxamine 5'-phosphate oxidase Exo_endo_phos_2 PF14529.6 RUS71584.1 - 4.2e-18 65.3 0.5 1.3e-17 63.7 0.5 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS71584.1 - 2.2e-15 56.8 0.0 4.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF229 PF02995.17 RUS71585.1 - 2.6e-89 300.1 0.3 1.1e-43 149.7 0.0 4.7 4 1 1 5 5 5 4 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS71585.1 - 0.0012 18.3 5.5 0.0014 18.1 4.0 1.9 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 RUS71585.1 - 0.017 14.7 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase SPX PF03105.19 RUS71585.1 - 0.098 12.6 15.1 0.35 10.7 15.0 1.8 1 1 0 1 1 1 0 SPX domain Spt20 PF12090.8 RUS71585.1 - 0.13 11.9 13.3 0.26 10.9 13.3 1.4 1 0 0 1 1 1 0 Spt20 family Chorion_2 PF03964.15 RUS71585.1 - 0.48 11.3 9.3 2.8 8.8 9.3 2.3 1 0 0 1 1 1 0 Chorion family 2 SR-25 PF10500.9 RUS71585.1 - 1.4 8.5 35.7 0.71 9.4 22.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3123 PF11321.8 RUS71585.1 - 1.4 9.6 4.4 4 8.2 4.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Pex14_N PF04695.13 RUS71585.1 - 1.6 9.4 15.3 2.3 8.8 6.7 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 RUS71585.1 - 2.2 7.0 12.2 0.72 8.6 3.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Androgen_recep PF02166.16 RUS71585.1 - 6.7 5.4 13.1 13 4.5 13.1 1.4 1 0 0 1 1 1 0 Androgen receptor SOG2 PF10428.9 RUS71585.1 - 7.5 5.6 23.1 1.4 8.1 12.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Holin_BlyA PF05102.12 RUS71585.1 - 7.8 6.5 6.3 49 4.0 0.3 2.9 1 1 2 3 3 3 0 holin, BlyA family AIG1 PF04548.16 RUS71589.1 - 3.2e-30 105.1 0.2 6.8e-30 104.0 0.2 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS71589.1 - 1.3e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS71589.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 RUS71589.1 - 0.061 13.6 0.2 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain CCDC53 PF10152.9 RUS71589.1 - 0.071 13.5 1.1 0.1 13.0 0.6 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex AIG1 PF04548.16 RUS71590.1 - 4.4e-43 147.1 0.3 4.4e-43 147.1 0.3 1.6 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS71590.1 - 6.9e-10 39.0 0.7 2.3e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS71590.1 - 0.0018 17.8 1.3 0.0066 16.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RUS71590.1 - 0.093 12.1 0.1 0.093 12.1 0.1 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 RUS71590.1 - 0.74 10.3 5.7 2.1 8.8 0.0 3.1 2 1 0 2 2 2 0 ABC transporter V_ATPase_I PF01496.19 RUS71590.1 - 0.79 7.6 11.5 1.1 7.0 11.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RsgA_GTPase PF03193.16 RUS71590.1 - 2.4 8.0 5.5 0.91 9.4 0.2 2.5 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 RUS71590.1 - 7.6 6.8 7.4 1.9 8.7 0.1 3.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Swi3 PF07962.12 RUS71591.1 - 0.063 13.3 0.4 0.13 12.2 0.3 1.6 1 1 1 2 2 2 0 Replication Fork Protection Component Swi3 RWD PF05773.22 RUS71592.1 - 8.8e-16 58.2 0.1 1.6e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain PolyA_pol_RNAbd PF12627.7 RUS71592.1 - 0.12 12.1 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Neur_chan_LBD PF02931.23 RUS71593.1 - 0.0086 15.5 0.4 2 7.8 0.1 2.7 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain DUF4529 PF15032.6 RUS71593.1 - 0.036 13.2 0.1 0.14 11.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4529) VWA PF00092.28 RUS71593.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 RUS71593.1 - 0.16 12.6 0.0 0.89 10.2 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain CBM_14 PF01607.24 RUS71593.1 - 1.5 9.1 4.8 4.5 7.5 4.8 1.9 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain TatD_DNase PF01026.21 RUS71594.1 - 1.4e-13 50.8 0.0 1.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Peptidase_S8 PF00082.22 RUS71596.1 - 3.7e-47 161.0 5.6 6e-47 160.4 5.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RUS71596.1 - 8.7e-20 70.5 0.0 2.4e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 RUS71596.1 - 3.1e-17 63.1 2.4 7.5e-17 61.9 2.4 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain Pkinase PF00069.25 RUS71597.1 - 1.6e-62 211.3 0.1 2.3e-62 210.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 RUS71597.1 - 3.2e-60 200.5 18.3 2e-13 50.8 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 RUS71597.1 - 5.9e-40 137.2 0.1 8.7e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 RUS71597.1 - 5.3e-29 99.4 23.0 2.7e-05 23.9 0.2 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 RUS71597.1 - 1.6e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS71597.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase bZIP_1 PF00170.21 RUS71597.1 - 0.00081 19.4 2.4 0.0018 18.3 2.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor PX PF00787.24 RUS71598.1 - 7e-14 51.8 0.1 1e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 PX domain Ig_3 PF13927.6 RUS71599.1 - 6.2e-33 113.2 1.9 2.1e-12 47.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS71599.1 - 2.6e-28 97.9 3.0 2.3e-14 53.2 0.1 4.6 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 RUS71599.1 - 4.2e-20 71.7 2.6 8.3e-05 22.7 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RUS71599.1 - 3.4e-18 65.8 3.5 4.9e-09 36.4 0.0 4.4 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RUS71599.1 - 2.5e-11 43.7 12.2 5e-05 23.4 0.4 7.1 4 4 1 5 5 5 3 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 RUS71599.1 - 2.9e-10 40.3 0.5 0.00065 19.9 0.0 3.5 3 0 0 3 3 3 3 Natural killer cell receptor 2B4 Ig_6 PF18452.1 RUS71599.1 - 9.8e-05 21.8 0.0 1.1 8.8 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin domain DUF3284 PF11687.8 RUS71599.1 - 0.014 15.2 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) C1-set PF07654.15 RUS71599.1 - 0.016 15.5 6.4 0.36 11.2 0.0 4.1 5 0 0 5 5 5 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 RUS71599.1 - 0.019 15.0 0.1 0.19 11.8 0.0 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Pilin_N PF07790.11 RUS71600.1 - 0.15 13.0 1.5 0.5 11.3 1.5 1.9 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3087 PF11286.8 RUS71600.1 - 7.2 6.0 6.8 0.42 10.1 0.9 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) DnaJ PF00226.31 RUS71601.1 - 2.1e-26 91.8 3.7 4.7e-26 90.7 3.7 1.6 1 0 0 1 1 1 1 DnaJ domain LON_substr_bdg PF02190.16 RUS71602.1 - 3.2e-18 66.4 0.0 5.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 RUS71602.1 - 1.3e-11 44.6 0.8 2.5e-11 43.7 0.8 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NCKAP5 PF15246.6 RUS71603.1 - 0.023 14.3 8.4 0.03 14.0 8.4 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Tox-ODYAM1 PF15642.6 RUS71603.1 - 0.13 11.2 5.0 0.15 11.0 5.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus CAF-1_p150 PF11600.8 RUS71603.1 - 0.13 11.9 25.1 0.17 11.6 25.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP-synt_B PF00430.18 RUS71603.1 - 0.36 10.9 23.0 0.53 10.4 23.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3450 PF11932.8 RUS71603.1 - 0.7 9.1 10.6 0.92 8.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PV-1 PF06637.11 RUS71603.1 - 0.85 8.4 11.2 1.1 8.1 11.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Flot PF15975.5 RUS71603.1 - 1.1 9.4 15.7 1.8 8.8 15.7 1.3 1 0 0 1 1 1 0 Flotillin Connexin PF00029.19 RUS71603.1 - 1.1 8.9 4.8 0.42 10.3 1.2 1.9 2 0 0 2 2 2 0 Connexin Endonuc_Holl PF10107.9 RUS71603.1 - 5.7 6.8 8.3 7.8 6.3 8.3 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase MRP-S26 PF14943.6 RUS71603.1 - 6.1 6.7 22.3 8.3 6.3 22.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Mis12 PF05859.12 RUS71604.1 - 4.3e-14 52.7 0.2 1.2e-13 51.3 0.1 1.8 2 1 0 2 2 2 1 Mis12 protein Wtap PF17098.5 RUS71604.1 - 0.0066 16.4 2.6 0.015 15.3 2.6 1.5 1 0 0 1 1 1 1 WTAP/Mum2p family Oxidored-like PF09791.9 RUS71604.1 - 0.022 14.4 0.2 0.053 13.2 0.2 1.7 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal TMF_TATA_bd PF12325.8 RUS71604.1 - 0.035 14.3 1.3 0.073 13.3 1.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PilO PF04350.13 RUS71604.1 - 0.051 13.7 0.5 0.092 12.9 0.5 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO ZapB PF06005.12 RUS71604.1 - 0.084 13.3 2.2 0.23 11.9 2.2 1.8 1 0 0 1 1 1 0 Cell division protein ZapB gag-asp_proteas PF13975.6 RUS71605.1 - 0.12 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Vps36-NZF-N PF16988.5 RUS71605.1 - 0.17 11.3 0.2 0.17 11.3 0.2 2.6 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-CCHC PF00098.23 RUS71605.1 - 0.23 11.6 11.5 0.25 11.5 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle RRM_1 PF00076.22 RUS71606.1 - 7.1e-16 57.8 0.1 1.2e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RUS71606.1 - 0.22 11.6 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 LA-virus_coat PF09220.10 RUS71607.1 - 4.3 5.8 4.3 97 1.4 0.1 3.9 2 2 1 4 4 4 0 L-A virus, major coat protein PLAT PF01477.23 RUS71611.1 - 0.038 14.5 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 PLAT/LH2 domain PKD_channel PF08016.12 RUS71614.1 - 1.8e-38 132.3 10.8 2.4e-38 131.9 10.8 1.1 1 0 0 1 1 1 1 Polycystin cation channel DAP PF15228.6 RUS71616.1 - 3.1e-25 89.2 11.1 3.6e-25 89.0 11.1 1.0 1 0 0 1 1 1 1 Death-associated protein Coa1 PF08695.10 RUS71617.1 - 7.1e-10 38.7 0.1 9.4e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Pkinase PF00069.25 RUS71618.1 - 2.1e-51 174.8 0.0 5.6e-51 173.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS71618.1 - 4.1e-26 91.8 0.0 7.4e-24 84.4 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase HicA_toxin PF07927.12 RUS71618.1 - 0.051 13.6 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, AMPKBI PF04739.15 RUS71618.1 - 0.12 12.7 0.1 13 6.2 0.0 2.6 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain DnaJ PF00226.31 RUS71619.1 - 1.9e-16 59.9 0.4 6.6e-11 42.2 0.1 2.2 1 1 1 2 2 2 2 DnaJ domain zf-CSL PF05207.13 RUS71619.1 - 4.2e-13 48.8 4.1 7.9e-13 47.9 4.1 1.5 1 0 0 1 1 1 1 CSL zinc finger FAM219A PF15260.6 RUS71619.1 - 0.29 11.5 3.3 0.5 10.7 2.7 1.7 1 1 0 1 1 1 0 Protein family FAM219A NAD_binding_8 PF13450.6 RUS71620.1 - 4.4e-16 58.9 0.3 8.8e-16 57.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 RUS71620.1 - 6.4e-16 58.7 0.0 2.7e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 RUS71620.1 - 6.8e-10 38.6 2.0 7.8e-08 31.8 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 RUS71620.1 - 8e-10 38.8 1.6 4.5e-06 26.5 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RUS71620.1 - 2.1e-07 30.6 0.1 5.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 RUS71620.1 - 1.4e-06 27.1 0.1 0.024 13.2 0.0 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor Thi4 PF01946.17 RUS71620.1 - 6e-05 22.4 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 RUS71620.1 - 0.00011 21.6 0.1 0.00022 20.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RUS71620.1 - 0.00013 21.4 1.2 0.00024 20.5 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 RUS71620.1 - 0.001 19.6 1.1 0.016 15.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS71620.1 - 0.002 16.9 0.8 0.0049 15.6 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 RUS71620.1 - 0.0029 16.8 3.6 0.011 14.8 0.5 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A MCRA PF06100.11 RUS71620.1 - 0.0039 16.1 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 MCRA family GMC_oxred_N PF00732.19 RUS71620.1 - 0.0046 16.4 0.5 0.012 15.0 0.1 1.8 2 0 0 2 2 2 1 GMC oxidoreductase AlaDh_PNT_C PF01262.21 RUS71620.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Suc_Fer-like PF06999.12 RUS71621.1 - 0.052 13.4 2.0 0.061 13.2 2.0 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like C5-epim_C PF06662.13 RUS71622.1 - 1.7e-67 226.6 0.0 2.7e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Tmemb_9 PF05434.11 RUS71623.1 - 9.2e-42 142.4 2.1 1.6e-41 141.6 2.1 1.4 1 0 0 1 1 1 1 TMEM9 Cortexin PF11057.8 RUS71623.1 - 0.017 14.9 0.3 0.042 13.7 0.3 1.6 1 0 0 1 1 1 0 Cortexin of kidney Baculo_11_kDa PF06143.11 RUS71623.1 - 0.023 14.3 1.9 0.035 13.7 0.8 1.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF5527 PF17665.1 RUS71623.1 - 0.048 13.2 1.3 0.088 12.3 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CD34_antigen PF06365.12 RUS71623.1 - 0.058 13.0 0.2 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 CD34/Podocalyxin family DUF5383 PF17355.2 RUS71623.1 - 5.5 7.4 5.6 2.3 8.6 1.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5383) Biopterin_H PF00351.21 RUS71624.1 - 4.5e-167 555.1 0.0 6.5e-167 554.6 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 RUS71624.1 - 9.9e-08 31.6 1.3 1.5e-07 31.1 0.3 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 RUS71624.1 - 0.015 15.9 1.3 0.07 13.7 1.1 2.1 2 0 0 2 2 2 0 ACT domain EB PF01683.18 RUS71625.1 - 2.3e-17 63.0 65.4 3.1e-07 30.6 7.4 6.2 3 1 3 6 6 6 6 EB module fn3 PF00041.21 RUS71625.1 - 1.3e-15 57.5 10.7 1.2e-08 35.2 1.2 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS71625.1 - 0.00015 22.3 11.6 0.0072 16.9 0.5 2.9 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 RUS71625.1 - 0.049 14.2 0.3 7 7.3 0.0 2.9 2 2 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Death_2 PF14786.6 RUS71626.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Tube Death domain zf-RVT PF13966.6 RUS71626.1 - 0.11 13.2 1.4 0.42 11.4 0.1 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase fn3 PF00041.21 RUS71627.1 - 7e-12 45.5 2.0 3e-05 24.3 0.6 3.0 3 1 1 4 4 4 2 Fibronectin type III domain LETM1 PF07766.13 RUS71628.1 - 9.6e-42 143.2 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 LETM1-like protein UBA PF00627.31 RUS71629.1 - 1.3e-22 79.3 2.9 2e-08 34.0 0.1 3.4 3 0 0 3 3 3 3 UBA/TS-N domain Ubiquitin_5 PF18037.1 RUS71629.1 - 1e-16 61.0 0.0 3.5e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like domain CUE PF02845.16 RUS71629.1 - 2.4e-06 27.1 0.1 0.12 12.1 0.0 3.6 3 0 0 3 3 3 2 CUE domain HOIP-UBA PF16678.5 RUS71629.1 - 6e-06 26.3 0.3 0.00021 21.3 0.2 2.6 2 0 0 2 2 2 1 HOIP UBA domain pair ubiquitin PF00240.23 RUS71629.1 - 4.9e-05 23.0 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 RUS71629.1 - 0.00048 19.9 0.0 3.1 7.7 0.0 3.4 3 0 0 3 3 3 2 UBA-like domain RPN7 PF10602.9 RUS71629.1 - 0.055 13.2 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 RUS71629.1 - 0.12 12.5 2.3 20 5.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS71629.1 - 0.24 11.7 2.8 32 4.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71629.1 - 5.1 7.8 6.9 3.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CSRNP_N PF16019.5 RUS71630.1 - 7.5e-88 294.1 14.7 7.5e-88 294.1 14.7 3.0 2 1 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus Pico_P2A PF00947.19 RUS71630.1 - 1.6 8.7 7.0 0.37 10.8 0.3 2.8 3 0 0 3 3 3 0 Picornavirus core protein 2A MFS_1 PF07690.16 RUS71631.1 - 0.00068 18.7 31.4 0.00068 18.7 31.4 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily N_Asn_amidohyd PF14736.6 RUS71631.1 - 0.055 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Fam20C PF06702.12 RUS71632.1 - 5.2e-69 232.4 4.4 5.4e-68 229.1 4.4 2.2 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 RUS71632.1 - 0.0018 17.2 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 FAM198 protein Cupin_8 PF13621.6 RUS71633.1 - 1.3e-09 38.2 3.4 2.5e-07 30.7 1.5 2.4 2 1 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 RUS71633.1 - 0.0004 20.0 0.7 0.0034 16.9 0.2 2.1 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 RUS71633.1 - 0.0032 17.1 0.4 0.0056 16.4 0.0 1.6 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 RUS71633.1 - 0.017 15.5 1.3 0.036 14.5 0.4 1.9 2 1 0 2 2 2 0 JmjC domain, hydroxylase Pkinase PF00069.25 RUS71634.1 - 1e-40 139.8 0.0 1.7e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS71634.1 - 6.3e-23 81.4 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS71634.1 - 7.9e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS71634.1 - 0.0015 17.4 1.1 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RUS71634.1 - 0.0024 17.9 0.0 1.1 9.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS71634.1 - 0.0042 16.1 0.1 0.0074 15.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PAT1 PF09770.9 RUS71634.1 - 9.2 4.4 11.1 15 3.7 11.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exo70 PF03081.15 RUS71635.1 - 6.3e-79 265.7 3.7 6.3e-79 265.7 3.7 2.3 2 1 1 3 3 3 1 Exo70 exocyst complex subunit COG6 PF06419.11 RUS71635.1 - 7e-05 21.3 12.2 0.043 12.0 2.7 3.3 3 1 0 3 3 3 2 Conserved oligomeric complex COG6 COG5 PF10392.9 RUS71635.1 - 0.00022 21.4 2.7 0.00022 21.4 2.7 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec34 PF04136.15 RUS71635.1 - 0.0023 17.8 1.3 0.0023 17.8 1.3 2.5 2 0 0 2 2 2 1 Sec34-like family Sec3_C PF09763.9 RUS71635.1 - 0.0051 15.3 6.7 0.027 12.9 2.4 2.5 2 0 0 2 2 2 1 Exocyst complex component Sec3 Baculo_PEP_C PF04513.12 RUS71635.1 - 0.11 12.5 1.9 0.42 10.7 1.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus P4Ha_N PF08336.11 RUS71635.1 - 0.18 11.8 14.2 0.21 11.6 0.3 3.8 3 1 1 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FlaC_arch PF05377.11 RUS71635.1 - 0.21 12.0 1.9 3.5 8.1 0.3 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 RUS71635.1 - 0.27 10.9 7.3 0.023 14.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 RUS71635.1 - 0.56 10.3 6.4 4.3 7.4 0.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FliJ PF02050.16 RUS71635.1 - 0.59 10.4 6.9 0.74 10.1 0.9 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein Flagellin_N PF00669.20 RUS71635.1 - 0.6 10.2 3.0 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region U1snRNP70_N PF12220.8 RUS71635.1 - 0.9 10.2 8.1 1.4 9.6 0.6 3.8 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Laminin_II PF06009.12 RUS71635.1 - 1.6 8.7 5.8 0.36 10.9 1.1 2.3 2 0 0 2 2 2 0 Laminin Domain II LUC7 PF03194.15 RUS71635.1 - 3.2 7.3 6.0 0.83 9.3 1.5 2.2 3 0 0 3 3 3 0 LUC7 N_terminus MBOAT PF03062.19 RUS71636.1 - 7.4e-28 97.9 9.0 1.5e-27 96.9 9.0 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LrgA PF03788.14 RUS71636.1 - 0.042 13.8 1.2 2.8 7.9 0.9 2.8 2 0 0 2 2 2 0 LrgA family DUF1925 PF09094.11 RUS71636.1 - 0.078 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) zf-CCHC PF00098.23 RUS71637.1 - 6.7e-13 48.1 46.6 1.2e-05 25.2 2.8 5.8 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 RUS71637.1 - 0.012 15.6 1.0 0.012 15.6 1.0 5.0 3 2 1 4 4 4 0 Zinc knuckle FISNA PF14484.6 RUS71637.1 - 0.85 9.9 5.1 17 5.7 1.3 2.9 2 0 0 2 2 2 0 Fish-specific NACHT associated domain zf-CCHC_4 PF14392.6 RUS71637.1 - 1.5 8.6 30.4 0.27 11.0 2.0 5.3 3 1 2 5 5 5 0 Zinc knuckle RF-1 PF00472.20 RUS71638.1 - 7.4e-22 77.5 0.1 1.2e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain Annexin PF00191.20 RUS71639.1 - 8.6e-41 137.9 0.7 5e-19 68.1 0.0 3.1 3 0 0 3 3 3 3 Annexin 7TM_GPCR_Srw PF10324.9 RUS71640.1 - 8.1e-26 91.0 22.0 1e-25 90.7 22.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS71640.1 - 1.6e-13 50.6 22.2 2e-13 50.3 22.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EVC2_like PF12297.8 RUS71640.1 - 0.085 11.5 1.7 0.068 11.8 0.4 1.4 1 1 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase_Tyr PF07714.17 RUS71641.1 - 1.3e-70 237.6 0.0 1.9e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS71641.1 - 2.6e-33 115.5 0.0 5.9e-33 114.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 RUS71641.1 - 1.1e-16 61.2 1.6 3.1e-07 30.9 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS71641.1 - 1.1e-10 41.7 2.7 0.00016 21.9 0.3 3.5 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS71641.1 - 1.8e-09 37.5 0.1 0.0036 17.3 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 RUS71641.1 - 2.8e-07 30.6 5.4 0.008 16.3 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 RUS71641.1 - 3.3e-07 30.5 0.6 0.017 15.2 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS71641.1 - 0.0017 18.6 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 RUS71641.1 - 0.0088 16.1 0.0 0.05 13.7 0.0 2.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain SPT6_acidic PF14632.6 RUS71641.1 - 0.033 14.8 1.3 0.058 14.0 1.3 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Ig_5 PF16681.5 RUS71641.1 - 0.033 14.6 0.0 6.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain TMEM51 PF15345.6 RUS71641.1 - 0.049 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4381 PF14316.6 RUS71641.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4244 PF14029.6 RUS71641.1 - 0.19 11.2 0.6 0.38 10.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Porin_3 PF01459.22 RUS71642.1 - 1.6e-19 70.5 0.0 1.9e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Fe-ADH PF00465.19 RUS71642.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase PDZ PF00595.24 RUS71643.1 - 6.4e-15 55.3 0.3 8.1e-15 55.0 0.3 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS71643.1 - 4.5e-13 48.8 0.1 6.8e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS71643.1 - 5e-09 36.4 0.1 6.8e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 PDZ domain RGS-like PF09128.11 RUS71644.1 - 4.7e-38 130.8 0.0 5.9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RGS PF00615.19 RUS71644.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain TauD PF02668.16 RUS71647.1 - 7.6e-36 124.3 0.0 9.9e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RUS71647.1 - 1.5e-10 41.5 0.1 3.1e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 RUS71647.1 - 0.00027 20.2 0.0 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 CsiD RVT_1 PF00078.27 RUS71649.1 - 1.4e-24 86.9 0.1 1.7e-24 86.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 RUS71650.1 - 9.5e-14 50.2 18.5 0.016 15.2 0.3 7.1 7 1 0 7 7 7 5 Leucine Rich repeat DUF89 PF01937.19 RUS71650.1 - 0.03 13.3 0.6 0.055 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 LRR_1 PF00560.33 RUS71650.1 - 2.6 8.9 9.5 20 6.3 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat Neur_chan_LBD PF02931.23 RUS71652.1 - 3.3e-88 294.7 0.5 2.9e-44 151.1 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS71652.1 - 2.7e-41 142.2 14.4 1.8e-22 80.6 0.7 3.3 4 1 0 4 4 4 2 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S30 PF01577.16 RUS71652.1 - 0.00011 21.9 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 Potyvirus P1 protease WavE PF07507.11 RUS71652.1 - 0.0097 15.1 0.4 3 6.9 0.1 2.2 2 0 0 2 2 2 2 WavE lipopolysaccharide synthesis ATP_Ca_trans_C PF12424.8 RUS71652.1 - 0.044 14.3 2.4 1.3 9.5 0.4 2.5 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal DUF5334 PF17268.2 RUS71652.1 - 0.088 13.1 1.0 3.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5334) GST_C_3 PF14497.6 RUS71653.1 - 1.6e-16 60.3 0.1 2.7e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS71653.1 - 9.5e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS71653.1 - 6.8e-07 29.4 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ada_Zn_binding PF02805.16 RUS71653.1 - 0.019 15.0 1.4 0.034 14.2 1.4 1.4 1 0 0 1 1 1 0 Metal binding domain of Ada GST_C_2 PF13410.6 RUS71653.1 - 0.037 14.1 0.0 0.077 13.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS71653.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RVT_1 PF00078.27 RUS71656.1 - 1.7e-24 86.6 0.0 2.8e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C1 PF00112.23 RUS71657.1 - 2.5e-82 276.2 4.6 3.1e-82 275.9 4.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RUS71657.1 - 1.3e-06 28.7 2.3 2.4e-06 27.9 2.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RUS71657.1 - 0.00014 20.8 2.3 0.011 14.5 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF4859 PF16151.5 RUS71657.1 - 0.15 11.9 5.3 4.5 7.2 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) ParcG PF10274.9 RUS71658.1 - 8.4e-84 280.2 0.0 1e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 RUS71658.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Peptidase_C107 PF17222.3 RUS71658.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Ribosomal_S15 PF00312.22 RUS71659.1 - 1.4e-11 44.4 0.5 2.9e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 Sugar_tr PF00083.24 RUS71660.1 - 2.1e-33 115.9 16.1 2.8e-33 115.5 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS71660.1 - 9.5e-30 103.7 46.1 1.4e-22 80.2 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 RUS71660.1 - 0.24 12.0 0.0 0.99 10.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 RUS71663.1 - 4.2e-10 39.7 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Laps PF10169.9 RUS71663.1 - 0.0047 17.5 0.0 0.0079 16.8 0.0 1.3 1 0 0 1 1 1 1 Learning-associated protein APOBEC3 PF18771.1 RUS71663.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 GpcrRhopsn4 PF10192.9 RUS71664.1 - 0.074 12.5 2.0 0.13 11.7 2.0 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Syntaxin-6_N PF09177.11 RUS71666.1 - 3.7e-35 120.4 2.0 3.7e-35 120.4 2.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RUS71666.1 - 2.4e-09 37.0 1.9 2.4e-09 37.0 1.9 2.2 2 0 0 2 2 2 1 SNARE domain KH_5 PF13184.6 RUS71666.1 - 0.0093 16.0 0.1 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 NusA-like KH domain Pex24p PF06398.11 RUS71666.1 - 0.041 12.9 0.6 0.041 12.9 0.6 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Orf78 PF06024.12 RUS71666.1 - 0.12 12.7 0.6 0.12 12.7 0.6 2.2 3 0 0 3 3 3 0 Orf78 (ac78) m04gp34like PF12216.8 RUS71666.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Immune evasion protein DUF2207 PF09972.9 RUS71666.1 - 0.14 10.9 0.2 0.3 9.8 0.1 1.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FliD_C PF07195.12 RUS71666.1 - 0.17 11.3 6.1 0.75 9.2 6.2 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus SKN1 PF03935.15 RUS71666.1 - 0.26 9.6 1.6 0.48 8.8 0.7 1.7 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) DUF2203 PF09969.9 RUS71666.1 - 0.37 11.5 6.4 1.7 9.4 0.8 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PBP1_TM PF14812.6 RUS71666.1 - 5.1 7.5 8.5 0.53 10.7 0.1 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.11 RUS71667.1 - 0.006 16.7 0.6 0.0062 16.7 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.19 RUS71667.1 - 2.1 7.7 8.3 2.9 7.3 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NmrA PF05368.13 RUS71668.1 - 1.5e-31 109.7 0.0 1.9e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RUS71668.1 - 3e-07 30.5 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_S18 PF01084.20 RUS71669.1 - 6.7e-17 61.5 0.0 1.8e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 DUF4660 PF15559.6 RUS71670.1 - 1.3e-08 35.1 12.5 1.6e-08 34.8 11.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4660) rRNA_processing PF08524.11 RUS71670.1 - 0.31 11.1 8.1 0.049 13.7 2.1 2.1 2 0 0 2 2 2 0 rRNA processing DUF866 PF05907.13 RUS71671.1 - 4.9e-55 185.7 0.4 5.5e-55 185.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LMBR1 PF04791.16 RUS71672.1 - 1.6e-164 548.7 21.9 1.8e-164 548.4 21.9 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein BSMAP PF12280.8 RUS71673.1 - 4e-36 125.0 3.5 7e-36 124.2 0.0 2.2 2 0 0 2 2 2 1 Brain specific membrane anchored protein Integrase_H2C2 PF17921.1 RUS71675.1 - 5.1e-17 61.7 0.3 1.1e-16 60.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS71675.1 - 1.5e-09 38.1 0.0 3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS71675.1 - 5.7e-05 23.2 0.3 0.00012 22.3 0.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Ank_2 PF12796.7 RUS71676.1 - 3.4e-130 424.9 18.9 7.3e-16 58.5 0.0 7.6 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS71676.1 - 5.6e-72 237.2 1.5 1.2e-10 41.7 0.0 10.7 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 RUS71676.1 - 3.6e-62 204.3 2.9 1.7e-05 25.1 0.0 14.3 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 RUS71676.1 - 1.1e-58 188.3 2.2 9.7e-05 22.5 0.0 14.9 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 RUS71676.1 - 3.9e-55 183.2 9.6 1.6e-10 41.0 0.0 10.6 3 3 8 11 11 11 10 Ankyrin repeats (many copies) PEGA PF08308.11 RUS71676.1 - 0.0067 16.3 0.0 17 5.4 0.0 3.6 3 0 0 3 3 3 1 PEGA domain Ribosomal_S6 PF01250.17 RUS71676.1 - 0.058 13.7 0.0 24 5.3 0.0 3.6 3 0 0 3 3 3 0 Ribosomal protein S6 PTS_IIA PF02255.16 RUS71676.1 - 0.09 12.8 0.1 4.2 7.5 0.2 3.2 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit Lectin_C PF00059.21 RUS71677.1 - 1.1e-11 45.4 0.2 2.1e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain C2 PF00168.30 RUS71678.1 - 5.5e-35 119.8 0.1 8.1e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 RUS71678.1 - 0.0036 17.2 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 IPTL-CTERM PF18203.1 RUS71678.1 - 1.1 9.3 4.4 2 8.4 4.4 1.4 1 0 0 1 1 1 0 IPTL-CTERM motif Phosphodiest PF01663.22 RUS71679.1 - 4.9e-26 92.2 0.2 5.6e-26 92.0 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.22 RUS71680.1 - 3.7e-18 66.2 0.0 4.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS71680.1 - 0.21 11.0 0.4 0.29 10.5 0.4 1.4 1 1 0 1 1 1 0 Sulfatase BAG PF02179.16 RUS71681.1 - 4.7e-06 26.9 0.2 1.1e-05 25.8 0.2 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 RUS71681.1 - 0.00021 21.0 0.0 0.0029 17.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 RUS71681.1 - 0.016 15.5 0.0 0.75 10.2 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin-like domain DUF4349 PF14257.6 RUS71681.1 - 0.017 14.6 3.5 0.018 14.5 0.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) Baculo_PEP_C PF04513.12 RUS71681.1 - 0.024 14.7 5.5 2.2 8.3 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 RUS71681.1 - 6.5 7.3 6.6 32 5.1 0.4 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 RUS71681.1 - 9.8 5.4 7.5 22 4.3 7.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PilJ PF13675.6 RUS71682.1 - 0.17 11.9 0.1 0.74 9.8 0.0 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RRM_1 PF00076.22 RUS71683.1 - 7.5e-20 70.5 0.1 1.5e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ets PF00178.22 RUS71686.1 - 8.1e-35 119.2 2.5 1.5e-34 118.3 0.4 2.2 2 0 0 2 2 2 1 Ets-domain GABP-alpha PF11620.8 RUS71686.1 - 4.6e-33 113.3 1.7 9.5e-33 112.3 1.7 1.6 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 RUS71686.1 - 2e-28 98.2 0.4 4.2e-28 97.1 0.4 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain WAP PF00095.21 RUS71687.1 - 0.0003 21.1 15.3 0.0003 21.1 15.3 3.1 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' H_lectin PF09458.10 RUS71688.1 - 0.00032 20.8 0.5 0.0013 18.9 0.5 2.0 1 1 0 1 1 1 1 H-type lectin domain SKA2 PF16740.5 RUS71688.1 - 0.036 13.8 3.6 1.2 8.9 0.7 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ApoC-I PF04691.12 RUS71688.1 - 0.038 13.9 0.4 0.61 10.1 0.0 2.8 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) AFT PF08731.11 RUS71688.1 - 0.32 11.4 1.7 0.79 10.1 1.7 1.7 1 0 0 1 1 1 0 Transcription factor AFT Presenilin PF01080.17 RUS71688.1 - 7 5.3 9.4 8.6 5.0 9.4 1.4 1 0 0 1 1 1 0 Presenilin Ig_2 PF13895.6 RUS71689.1 - 4.2e-05 23.8 0.2 8.7e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 RUS71689.1 - 0.0002 21.9 0.1 0.00034 21.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS71689.1 - 0.00082 19.4 0.1 0.0017 18.4 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain DUF1381 PF07129.11 RUS71689.1 - 0.024 14.5 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) ig PF00047.25 RUS71689.1 - 0.024 14.8 0.8 0.074 13.2 0.8 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Sigma70_ner PF04546.13 RUS71689.1 - 0.15 11.9 3.1 0.19 11.6 3.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 RUS71689.1 - 0.27 11.0 12.3 0.37 10.5 12.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 RUS71689.1 - 0.29 10.8 1.3 0.57 9.8 1.3 1.6 1 0 0 1 1 1 0 FAM176 family zf-H2C2_2 PF13465.6 RUS71690.1 - 4.6e-54 178.5 97.6 3.7e-07 30.3 1.2 12.4 12 0 0 12 12 12 11 Zinc-finger double domain zf-C2H2 PF00096.26 RUS71690.1 - 5.6e-37 124.2 109.7 6.4e-05 23.2 1.4 12.6 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS71690.1 - 1.9e-21 74.9 113.5 0.0029 18.3 0.5 13.0 13 0 0 13 13 13 10 C2H2-type zinc finger zf-met PF12874.7 RUS71690.1 - 6.3e-13 48.6 79.3 0.015 15.7 1.7 12.6 13 0 0 13 13 13 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS71690.1 - 2.6e-12 46.7 81.8 0.0029 17.9 0.4 13.4 12 2 1 13 13 13 8 Zinc-finger double-stranded RNA-binding BolA PF01722.18 RUS71690.1 - 1.1e-05 25.6 25.1 0.03 14.6 0.4 6.4 6 0 0 6 6 6 3 BolA-like protein zf-C2H2_6 PF13912.6 RUS71690.1 - 0.0011 18.9 87.6 0.027 14.5 2.6 11.8 13 0 0 13 13 13 7 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 RUS71690.1 - 0.43 10.7 0.1 0.43 10.7 0.1 8.7 9 3 1 10 10 10 0 Sec23/Sec24 zinc finger TFIIA PF03153.13 RUS71690.1 - 0.64 10.0 16.3 1.3 8.9 16.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_5 PF00266.19 RUS71691.1 - 7.4e-48 163.4 0.0 7.5e-47 160.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Lin-8 PF03353.15 RUS71692.1 - 0.12 11.9 4.2 0.15 11.6 4.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 RUS71692.1 - 0.16 11.5 4.3 0.24 11.0 4.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC2_membrane_3 PF12698.7 RUS71692.1 - 0.17 10.9 0.2 0.22 10.6 0.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DHC_N2 PF08393.13 RUS71693.1 - 0.0055 15.9 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Herpes_UL32 PF06070.11 RUS71693.1 - 0.12 10.1 0.3 0.17 9.6 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF4611 PF15387.6 RUS71693.1 - 2.5 8.4 6.2 0.17 12.1 0.4 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) LRR_9 PF14580.6 RUS71694.1 - 1.1e-50 171.5 36.0 9.1e-12 44.8 2.1 8.0 5 3 2 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 RUS71694.1 - 2.7e-49 164.3 105.5 6.2e-06 26.5 0.7 16.9 12 3 7 20 20 20 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS71694.1 - 1.9e-34 117.2 102.7 1.6e-09 37.4 1.1 13.8 8 4 7 15 15 15 12 Leucine rich repeat LRR_5 PF13306.6 RUS71694.1 - 0.0041 17.1 7.8 3.6 7.6 0.6 4.6 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) SNAP PF14938.6 RUS71695.1 - 9.7e-111 369.7 17.6 1.1e-110 369.5 17.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RUS71695.1 - 2e-12 47.2 5.0 3.1e-07 30.6 0.2 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS71695.1 - 6.5e-07 28.9 13.3 0.055 13.3 0.0 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS71695.1 - 1.1e-06 28.2 16.3 0.047 13.8 0.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS71695.1 - 1.5e-06 28.5 9.1 0.024 15.2 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS71695.1 - 2.2e-05 24.3 14.1 0.069 13.4 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS71695.1 - 0.00011 21.9 5.7 1.1 9.4 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS71695.1 - 0.00017 21.4 5.4 1.6 8.7 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS71695.1 - 0.00066 19.9 3.8 0.28 11.5 0.7 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS71695.1 - 0.0017 19.0 6.7 0.1 13.5 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat NSF PF02071.20 RUS71695.1 - 0.0017 18.7 27.7 1.9 9.6 0.3 8.0 8 0 0 8 8 7 2 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 RUS71695.1 - 0.0071 17.0 3.4 1.2 9.8 1.2 3.9 2 2 0 2 2 2 1 Tetratricopeptide repeat DUF2076 PF09849.9 RUS71695.1 - 0.0075 16.4 0.3 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Spatacsin_C PF14649.6 RUS71695.1 - 0.039 13.0 8.3 0.36 9.9 7.0 2.5 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_11 PF13414.6 RUS71695.1 - 0.12 12.1 11.0 0.8 9.4 0.0 4.4 4 1 1 5 5 5 0 TPR repeat ANAPC5 PF12862.7 RUS71695.1 - 0.15 12.1 3.5 0.89 9.7 0.6 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 RPN7 PF10602.9 RUS71695.1 - 0.17 11.6 8.5 0.091 12.5 2.6 2.7 2 1 1 3 3 2 0 26S proteasome subunit RPN7 UpxZ PF06603.11 RUS71695.1 - 0.22 11.8 2.4 0.5 10.7 1.2 2.3 2 1 1 3 3 2 0 UpxZ family of transcription anti-terminator antagonists UVR PF02151.19 RUS71695.1 - 0.76 9.6 8.0 13 5.7 0.1 4.5 5 0 0 5 5 5 0 UvrB/uvrC motif TPR_19 PF14559.6 RUS71695.1 - 0.79 10.3 5.6 8.1 7.0 0.0 3.9 3 2 1 4 4 3 0 Tetratricopeptide repeat Gal_Lectin PF02140.18 RUS71698.1 - 5.5e-23 81.2 4.4 4e-14 52.8 0.6 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 RUS71698.1 - 5.9e-06 26.0 0.0 5.9e-06 26.0 0.0 3.8 3 1 0 3 3 3 1 FAM176 family DNA_pol_phi PF04931.13 RUS71698.1 - 0.013 13.6 43.4 0.019 13.1 43.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS71698.1 - 0.088 11.0 32.5 0.12 10.5 32.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3395 PF11875.8 RUS71698.1 - 0.097 12.6 0.1 23 4.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3395) CDC45 PF02724.14 RUS71698.1 - 2.7 6.2 28.6 4.2 5.5 28.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS71698.1 - 5.7 5.3 27.0 8.3 4.7 27.0 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 RUS71698.1 - 5.9 5.6 10.3 8.7 5.0 10.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1147 PF06615.11 RUS71699.1 - 7.5 6.7 21.5 12 6.1 1.0 5.9 3 3 3 6 6 6 0 Protein of unknown function (DUF1147) Cornifin PF02389.15 RUS71700.1 - 0.003 17.8 10.8 0.0036 17.5 10.8 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family TetR_C_35 PF18556.1 RUS71700.1 - 0.066 13.3 0.0 22 5.2 0.0 2.6 1 1 2 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain LRR_2 PF07723.13 RUS71700.1 - 0.072 13.8 54.5 1.7 9.5 1.6 9.0 2 2 8 10 10 10 0 Leucine Rich Repeat RdRP_2 PF00978.21 RUS71700.1 - 1.1 8.1 11.4 2.1 7.2 1.7 2.6 1 1 1 2 2 2 0 RNA dependent RNA polymerase 7tm_1 PF00001.21 RUS71702.1 - 2.4e-20 73.0 5.9 3.7e-19 69.1 1.7 2.0 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.22 RUS71707.1 - 2.4e-13 49.7 0.0 3.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RUS71707.1 - 4.6e-07 29.6 1.6 8.4e-07 28.8 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS71707.1 - 0.00033 20.4 1.3 0.00051 19.8 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle SET_assoc PF11767.8 RUS71707.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-CCCH_3 PF15663.5 RUS71708.1 - 1.2e-28 99.6 9.0 1.2e-28 99.6 9.0 2.0 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 RUS71708.1 - 5.5 7.6 20.9 12 6.5 0.1 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Skp1 PF01466.19 RUS71709.1 - 2.5e-29 101.1 0.6 5.5e-29 100.0 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RUS71709.1 - 7.6e-29 99.7 0.3 2e-28 98.3 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PI-PLC-Y PF00387.19 RUS71710.1 - 2e-37 128.0 0.0 3.9e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 RUS71710.1 - 1.4e-20 73.4 0.1 4.1e-20 71.9 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain C2 PF00168.30 RUS71710.1 - 1.8e-18 66.7 0.1 7.6e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain Pox_Ag35 PF03286.14 RUS71710.1 - 0.09 12.6 5.4 0.13 12.0 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HA2 PF04408.23 RUS71711.1 - 1.3e-13 51.2 0.1 3.1e-13 50.0 0.1 1.8 1 1 1 2 2 2 1 Helicase associated domain (HA2) PALP PF00291.25 RUS71711.1 - 0.034 13.5 0.0 0.039 13.4 0.0 1.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Phytoreo_S7 PF07236.11 RUS71711.1 - 0.083 11.2 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein 7tm_1 PF00001.21 RUS71712.1 - 7.1e-13 48.5 13.3 1e-12 48.0 13.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ig_3 PF13927.6 RUS71713.1 - 1.9e-23 82.8 0.0 2.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS71713.1 - 1.3e-21 76.5 0.0 2.1e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS71713.1 - 2e-15 56.9 0.0 3.2e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS71713.1 - 1.2e-11 44.6 0.1 7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS71713.1 - 2.4e-05 24.3 0.1 0.00034 20.6 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS71713.1 - 4.4e-05 23.6 0.1 0.0063 16.7 0.0 3.0 2 2 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 RUS71713.1 - 5.9e-05 23.4 0.0 0.02 15.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 RUS71713.1 - 0.058 13.0 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain LRR_4 PF12799.7 RUS71715.1 - 7.9e-07 29.3 8.1 4.1e-05 23.9 2.9 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS71715.1 - 0.0009 19.0 4.7 0.0045 16.7 4.5 1.9 1 1 0 1 1 1 1 Leucine rich repeat HMMR_N PF15905.5 RUS71716.1 - 0.0016 18.0 17.5 0.0016 18.0 17.5 11.2 4 3 4 10 10 10 3 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 RUS71716.1 - 0.0056 16.9 13.9 0.0056 16.9 13.9 14.2 5 2 8 13 13 13 6 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 RUS71716.1 - 0.022 14.9 0.1 0.022 14.9 0.1 15.6 17 3 2 20 20 20 0 JNK-interacting protein leucine zipper II Qua1 PF16274.5 RUS71716.1 - 1.3 8.9 8.1 4.9 7.1 0.2 5.0 5 0 0 5 5 5 0 Qua1 domain Filament PF00038.21 RUS71717.1 - 0.0023 17.5 50.1 0.024 14.2 32.4 3.0 2 1 0 2 2 2 2 Intermediate filament protein OmpH PF03938.14 RUS71717.1 - 0.0026 18.1 50.3 0.18 12.1 7.4 3.5 3 0 0 3 3 3 2 Outer membrane protein (OmpH-like) Spc7 PF08317.11 RUS71717.1 - 0.0099 14.8 50.5 0.26 10.1 7.4 3.3 3 0 0 3 3 3 3 Spc7 kinetochore protein Gp-FAR-1 PF05823.12 RUS71717.1 - 0.013 15.8 0.8 0.013 15.8 0.8 3.3 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ADIP PF11559.8 RUS71717.1 - 0.019 15.1 55.4 0.2 11.7 18.1 4.0 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Cnn_1N PF07989.11 RUS71717.1 - 0.024 14.8 5.8 0.024 14.8 5.8 6.2 2 2 4 6 6 5 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 RUS71717.1 - 0.033 14.0 1.8 0.033 14.0 1.8 6.3 5 2 2 7 7 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor FAM184 PF15665.5 RUS71717.1 - 0.036 13.8 56.1 0.035 13.9 11.6 3.4 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B SlyX PF04102.12 RUS71717.1 - 0.2 12.3 53.2 0.49 11.0 3.9 7.1 3 3 4 7 7 7 0 SlyX UPF0242 PF06785.11 RUS71717.1 - 0.48 10.5 59.4 0.096 12.8 12.4 3.6 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin_1 PF12718.7 RUS71717.1 - 0.48 10.6 63.4 0.034 14.3 9.5 5.2 3 2 2 5 5 5 0 Tropomyosin like Myosin_tail_1 PF01576.19 RUS71717.1 - 0.57 7.9 54.0 0.025 12.4 20.6 3.1 2 1 1 3 3 3 0 Myosin tail DUF1664 PF07889.12 RUS71717.1 - 1.5 8.8 25.1 0.88 9.6 7.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4686 PF15742.5 RUS71717.1 - 1.8 7.6 61.7 0.048 12.8 41.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4686) Lebercilin PF15619.6 RUS71717.1 - 2.2 7.9 59.8 3.3 7.3 19.6 3.7 3 2 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMCO5 PF14992.6 RUS71717.1 - 6 6.4 39.2 6.6 6.2 14.0 2.5 1 1 1 2 2 2 0 TMCO5 family Fez1 PF06818.15 RUS71717.1 - 9.4 6.6 52.8 12 6.2 11.0 3.1 1 1 2 3 3 3 0 Fez1 Leu_zip PF15294.6 RUS71717.1 - 9.8 5.6 51.3 2 7.8 6.1 3.6 1 1 3 4 4 4 0 Leucine zipper Trypsin_2 PF13365.6 RUS71718.1 - 4.5e-05 24.4 0.2 7.7e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PA28_alpha PF02251.18 RUS71719.1 - 0.013 15.5 0.0 27 4.9 0.0 3.6 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit Beta-lactamase PF00144.24 RUS71720.1 - 3.4e-50 171.1 0.0 4.7e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF2563 PF10817.8 RUS71720.1 - 0.038 14.6 0.0 0.094 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) Ank_2 PF12796.7 RUS71722.1 - 2.1e-27 95.5 0.5 2e-07 31.5 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS71722.1 - 2.9e-23 81.6 3.9 4.3e-09 36.4 0.0 6.8 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS71722.1 - 1.9e-21 76.1 2.2 2.6e-07 31.0 0.1 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Patatin PF01734.22 RUS71722.1 - 1.8e-18 67.4 0.5 1.2e-17 64.8 0.5 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ank PF00023.30 RUS71722.1 - 3.9e-17 61.8 5.8 0.073 13.6 0.0 8.0 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 RUS71722.1 - 2.8e-14 51.8 1.7 0.23 12.1 0.0 8.0 8 0 0 8 8 8 2 Ankyrin repeat Nefa_Nip30_N PF10187.9 RUS71722.1 - 0.00062 20.1 4.6 0.001 19.4 4.6 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4456 PF14644.6 RUS71722.1 - 0.015 15.0 0.4 0.026 14.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) HrpJ PF07201.11 RUS71722.1 - 0.062 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 HrpJ-like domain DUF4795 PF16043.5 RUS71722.1 - 0.09 12.4 0.4 0.17 11.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) SRR1 PF07985.12 RUS71723.1 - 1.2e-17 63.7 0.2 1.6e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 SRR1 DND1_DSRM PF14709.7 RUS71723.1 - 0.093 13.0 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ARTD15_N PF18084.1 RUS71724.1 - 0.0013 18.9 4.1 38 4.6 0.2 6.1 1 1 5 6 6 6 2 ARTD15 N-terminal domain MgtE_N PF03448.17 RUS71724.1 - 0.067 13.8 0.2 1.7 9.3 0.1 2.1 1 1 1 2 2 2 0 MgtE intracellular N domain PhyH PF05721.13 RUS71725.1 - 3.6e-12 47.0 0.0 5.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FlaC_arch PF05377.11 RUS71725.1 - 0.014 15.8 0.0 14 6.2 0.0 2.7 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) DUF4744 PF15918.5 RUS71726.1 - 5.4e-05 23.9 4.0 1.6 9.6 0.1 3.5 2 2 1 3 3 3 3 Domain of unknown function (DUF4744) Hemocyanin_M PF00372.19 RUS71726.1 - 0.06 12.5 1.9 31 3.6 0.0 4.1 2 2 5 7 7 7 0 Hemocyanin, copper containing domain MSG PF02349.15 RUS71726.1 - 0.061 13.5 31.9 1.7 8.9 2.2 5.1 2 2 4 6 6 6 0 Major surface glycoprotein Chlam_OMP3 PF03503.13 RUS71726.1 - 0.21 11.9 43.2 80 3.7 0.1 11.0 3 3 8 11 11 11 0 Chlamydia cysteine-rich outer membrane protein 3 HLH PF00010.26 RUS71728.1 - 2.8e-13 49.6 3.3 5.7e-13 48.6 3.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.16 RUS71728.1 - 1.1e-09 39.3 0.7 1.1e-09 39.3 0.7 3.1 3 0 0 3 3 3 1 Myogenic Basic domain WD40_4 PF16300.5 RUS71729.1 - 0.11 12.5 17.3 24 4.9 0.0 7.9 10 0 0 10 10 10 0 Type of WD40 repeat CagY_I PF14585.6 RUS71732.1 - 0.27 11.4 14.0 20 5.4 0.2 5.1 5 1 0 6 6 6 0 CagY type 1 repeat Sulfatase PF00884.23 RUS71733.1 - 6.2e-71 239.3 0.2 2e-70 237.6 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 RUS71733.1 - 0.036 13.7 0.0 0.35 10.4 0.0 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 RUS71733.1 - 0.043 14.5 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Tubulin PF00091.25 RUS71734.1 - 9.4e-68 228.3 0.0 1.3e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS71734.1 - 3.9e-52 175.7 0.0 6.4e-52 175.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS71734.1 - 0.0034 17.1 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Ntox43 PF15537.6 RUS71735.1 - 0.012 15.6 0.8 0.71 9.9 0.1 2.5 1 1 1 2 2 2 0 Bacterial toxin 43 C6_DPF PF10170.9 RUS71738.1 - 2.2 8.7 9.3 32 5.0 3.2 3.2 1 1 1 2 2 2 0 Cysteine-rich domain ZZ PF00569.17 RUS71738.1 - 7.2 6.5 7.9 78 3.2 0.2 3.5 2 1 1 3 3 3 0 Zinc finger, ZZ type LSM PF01423.22 RUS71741.1 - 8.9e-20 70.2 0.2 1.5e-19 69.4 0.2 1.4 1 0 0 1 1 1 1 LSM domain Abhydrolase_5 PF12695.7 RUS71742.1 - 3.8e-07 30.0 0.0 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family 7tm_1 PF00001.21 RUS71743.1 - 1.2e-38 132.9 8.7 1.7e-38 132.5 8.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS71743.1 - 6.6e-08 32.6 5.3 2.3e-07 30.8 4.0 2.0 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS71743.1 - 5.1e-06 26.1 9.0 0.0016 17.8 4.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS71743.1 - 1.5e-05 24.8 9.5 1.5e-05 24.8 9.5 1.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4395 PF14340.6 RUS71743.1 - 1.1 9.6 12.3 0.97 9.8 0.6 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4395) Na_H_antiport_1 PF06965.12 RUS71743.1 - 3.9 6.2 12.8 0.43 9.4 5.0 2.1 2 0 0 2 2 2 0 Na+/H+ antiporter 1 DUF3035 PF11233.8 RUS71744.1 - 0.0013 19.0 0.2 0.002 18.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3035) RuBisCO_small PF00101.20 RUS71745.1 - 0.0075 16.2 8.3 13 5.9 0.1 4.1 1 1 3 4 4 4 4 Ribulose bisphosphate carboxylase, small chain potato_inhibit PF00280.18 RUS71745.1 - 2.9 8.7 9.8 8.9 7.1 0.6 2.6 1 1 2 3 3 3 0 Potato inhibitor I family GST_N_3 PF13417.6 RUS71746.1 - 1.2e-06 28.8 0.0 2.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS71746.1 - 9.3e-06 25.9 0.1 2.5e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS71746.1 - 1.1e-05 25.3 0.1 2.9e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS71746.1 - 0.0027 17.9 0.2 0.11 12.7 0.0 2.7 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain Prok-RING_4 PF14447.6 RUS71746.1 - 0.06 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1972 PF09314.11 RUS71746.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) UCH PF00443.29 RUS71747.1 - 3.5e-25 89.0 0.0 2.9e-14 53.2 0.0 3.5 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS71747.1 - 2.4e-13 50.4 1.3 4.1e-13 49.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NopRA1 PF16201.5 RUS71750.1 - 3.3e-18 66.0 0.6 5.3e-18 65.3 0.6 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 CDC45 PF02724.14 RUS71750.1 - 0.013 13.8 14.5 0.019 13.3 14.5 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RUS71750.1 - 1.2 8.4 32.4 0.098 12.0 25.0 2.1 2 0 0 2 2 2 0 BUD22 Macoilin PF09726.9 RUS71750.1 - 3.7 6.0 13.3 4.8 5.6 13.3 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 RUS71750.1 - 6.2 4.8 8.2 8.4 4.4 8.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WAP PF00095.21 RUS71751.1 - 1.4e-07 31.7 15.3 1.4e-07 31.7 15.3 4.8 5 1 0 5 5 5 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Antistasin PF02822.14 RUS71751.1 - 2.8e-05 24.6 9.8 2.8e-05 24.6 9.8 5.6 4 1 0 4 4 4 1 Antistasin family fn3 PF00041.21 RUS71753.1 - 2e-86 284.5 38.2 1.8e-09 37.8 0.1 14.1 13 1 1 14 14 14 13 Fibronectin type III domain Y_phosphatase PF00102.27 RUS71753.1 - 5e-79 265.2 0.0 8.7e-79 264.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 RUS71753.1 - 7.7e-13 48.8 33.1 0.15 12.7 3.3 12.6 10 4 0 11 11 11 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS71753.1 - 9.6e-08 32.3 0.5 5.3 7.4 0.0 7.8 9 0 0 9 9 8 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 RUS71753.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4998 PF16389.5 RUS71753.1 - 0.002 17.8 0.6 0.95 9.0 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function DUF560 PF04575.13 RUS71753.1 - 0.036 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF560) CBM_2 PF00553.19 RUS71753.1 - 0.045 14.0 0.5 0.23 11.8 0.5 2.3 1 0 0 1 1 1 0 Cellulose binding domain DUF1410 PF07198.11 RUS71753.1 - 0.14 12.7 0.2 31 5.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1410) CBM_4_9 PF02018.17 RUS71753.1 - 0.15 12.3 12.7 6 7.1 0.9 5.8 7 1 0 7 7 7 0 Carbohydrate binding domain Tissue_fac PF01108.17 RUS71753.1 - 2.7 7.9 14.8 0.35 10.7 0.7 5.0 6 1 1 7 7 7 0 Tissue factor fn3 PF00041.21 RUS71754.1 - 7.1e-08 32.7 0.6 1.3e-06 28.6 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Crystall_2 PF09076.10 RUS71754.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Beta/Gamma crystallin L31 PF09784.9 RUS71756.1 - 0.027 14.9 0.8 0.15 12.5 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 RR_TM4-6 PF06459.12 RUS71757.1 - 1.1 9.0 31.5 0.74 9.6 23.8 2.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 RUS71757.1 - 8.1 5.8 16.2 6 6.2 14.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DASH_Duo1 PF08651.10 RUS71758.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF2645 PF10840.8 RUS71758.1 - 0.18 12.4 4.8 34 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) EF-hand_7 PF13499.6 RUS71759.1 - 6.9e-12 45.6 1.4 9.3e-08 32.4 0.3 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS71759.1 - 3.5e-07 29.3 0.7 6.2e-06 25.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 RUS71759.1 - 1.9e-06 27.1 0.2 5.3e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS71759.1 - 1.9e-05 24.2 0.6 0.0014 18.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RUS71759.1 - 7.9e-05 22.4 0.8 0.00021 21.1 0.7 1.9 1 1 0 1 1 1 1 EF-hand domain pair 2Fe-2S_thioredx PF01257.19 RUS71759.1 - 0.029 14.2 0.0 0.092 12.6 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin GLTP PF08718.11 RUS71760.1 - 2.1e-46 157.9 0.8 3.4e-46 157.2 0.8 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF223 PF02721.14 RUS71760.1 - 0.0014 18.9 0.7 0.0033 17.7 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF223 DALR_2 PF09190.11 RUS71760.1 - 0.14 12.7 0.1 14 6.2 0.0 3.1 3 0 0 3 3 3 0 DALR domain DFF40 PF09230.10 RUS71761.1 - 1.3e-57 195.1 0.6 1.4e-57 194.9 0.6 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa PAX PF00292.18 RUS71762.1 - 2.5e-28 98.5 3.7 1.8e-27 95.7 3.7 2.1 1 1 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 RUS71762.1 - 1.6e-22 79.1 6.0 1.6e-22 79.1 6.0 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS71762.1 - 2e-05 24.4 1.7 5.2e-05 23.0 0.8 2.2 3 0 0 3 3 3 1 Homeobox KN domain HTH_23 PF13384.6 RUS71762.1 - 0.034 13.9 2.9 0.16 11.8 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Sulfatase PF00884.23 RUS71764.1 - 7.5e-13 48.5 0.8 7.9e-13 48.5 0.8 1.0 1 0 0 1 1 1 1 Sulfatase Snf7 PF03357.21 RUS71765.1 - 4.1e-41 140.5 26.1 6.1e-41 139.9 26.1 1.2 1 0 0 1 1 1 1 Snf7 Secretogranin_V PF05281.11 RUS71765.1 - 0.034 13.8 0.8 0.034 13.8 0.8 1.5 1 1 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) DUF3585 PF12130.8 RUS71765.1 - 0.11 12.6 12.1 0.24 11.5 12.0 1.7 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain ATP-cone PF03477.16 RUS71765.1 - 1.3 9.6 10.5 2.9 8.5 1.4 2.6 1 1 1 2 2 2 0 ATP cone domain Amino_oxidase PF01593.24 RUS71766.1 - 1e-123 414.0 0.0 1.3e-122 410.3 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 RUS71766.1 - 1.2e-17 64.0 0.0 7.6e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 RUS71766.1 - 5.9e-13 48.8 0.9 1.4e-12 47.7 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS71766.1 - 6.3e-08 32.6 0.0 2.4e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RUS71766.1 - 2.5e-06 26.9 0.2 5.9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 RUS71766.1 - 4.1e-06 26.2 0.3 4.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS71766.1 - 0.00011 21.6 1.2 0.00046 19.6 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS71766.1 - 0.00011 22.7 2.6 0.0026 18.3 0.6 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RUS71766.1 - 0.00012 21.5 2.0 0.00022 20.6 2.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 RUS71766.1 - 0.00016 20.9 1.2 0.00029 20.0 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RUS71766.1 - 0.00024 20.0 0.3 0.00024 20.0 0.3 2.3 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 RUS71766.1 - 0.00053 19.3 0.1 0.001 18.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 RUS71766.1 - 0.0011 18.1 0.9 0.0025 16.9 0.9 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RUS71766.1 - 0.0037 16.4 0.2 0.0059 15.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 RUS71766.1 - 0.013 14.9 6.0 0.016 14.5 4.3 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 RUS71766.1 - 0.34 10.8 3.6 0.16 11.8 0.5 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shugoshin_C PF07557.11 RUS71766.1 - 0.47 10.3 3.3 1 9.2 3.3 1.6 1 0 0 1 1 1 0 Shugoshin C terminus F-protein PF00469.20 RUS71766.1 - 8.9 5.8 9.6 0.3 10.6 2.3 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DHC_N1 PF08385.12 RUS71767.1 - 2.3e-181 604.3 17.9 1.2e-179 598.6 11.5 3.4 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RUS71767.1 - 1e-144 481.5 0.0 5.3e-144 479.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS71767.1 - 8.9e-127 423.5 5.9 8.9e-127 423.5 5.9 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RUS71767.1 - 1.2e-95 320.3 0.0 4.7e-95 318.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RUS71767.1 - 1e-89 300.3 0.0 4.2e-89 298.3 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RUS71767.1 - 7.5e-69 230.9 4.4 1.5e-64 216.8 0.2 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RUS71767.1 - 5e-56 189.0 0.1 1.2e-55 187.7 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_9 PF12781.7 RUS71767.1 - 1.5e-43 148.5 11.6 3.7e-43 147.2 1.7 4.4 4 0 0 4 4 3 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 RUS71767.1 - 3.8e-41 139.9 0.8 5.2e-40 136.2 0.0 3.6 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RUS71767.1 - 8.2e-28 97.4 20.4 5.7e-18 65.0 1.2 2.8 3 0 0 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 RUS71767.1 - 8.2e-22 77.3 0.0 3.7e-21 75.2 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RUS71767.1 - 4.6e-20 72.0 0.0 1.1e-17 64.4 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS71767.1 - 4.8e-20 72.0 0.0 1.4e-06 28.4 0.0 5.2 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS71767.1 - 6.1e-06 26.7 0.1 4 7.9 0.0 5.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS71767.1 - 0.0012 19.2 2.7 35 4.7 0.0 5.9 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.26 RUS71767.1 - 0.011 15.4 0.2 0.74 9.5 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 RUS71767.1 - 0.07 13.5 4.9 26 5.1 0.0 5.5 6 0 0 6 6 5 0 AAA ATPase domain HEPN_AbiU2 PF18734.1 RUS71767.1 - 0.075 12.5 1.2 0.5 9.8 0.2 3.2 3 0 0 3 3 2 0 AbiU2 ATPase PF06745.13 RUS71767.1 - 3.7 6.8 7.3 7.6 5.8 0.0 4.3 4 0 0 4 4 4 0 KaiC Lipocalin PF00061.23 RUS71768.1 - 1.8e-05 25.0 0.0 1.9e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 RUS71768.1 - 0.004 17.1 0.1 0.006 16.5 0.1 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 RUS71768.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Triabin DGF-1_4 PF11024.8 RUS71768.1 - 0.025 15.4 0.0 0.029 15.2 0.0 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Smr PF01713.21 RUS71769.1 - 1.9e-07 31.4 0.0 2.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Smr domain Glycos_transf_1 PF00534.20 RUS71770.1 - 9.9e-38 129.4 0.0 1.5e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RUS71770.1 - 2.1e-19 70.3 0.0 3.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RUS71770.1 - 2.8e-16 60.0 0.0 4.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RUS71770.1 - 3.4e-08 34.1 0.0 6.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RUS71770.1 - 8.5e-06 26.1 0.0 2.1e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.5 RUS71770.1 - 0.0019 17.9 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl-transferase family 4 UBA_4 PF14555.6 RUS71771.1 - 9.1e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 RUS71771.1 - 0.22 10.7 14.0 0.33 10.1 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Adaptin_N PF01602.20 RUS71773.1 - 2.3e-171 570.9 13.0 3.3e-171 570.4 13.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 RUS71773.1 - 2.3e-42 144.7 0.1 5.6e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 RUS71773.1 - 1.1e-24 87.3 7.8 1.5e-19 70.6 0.7 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RUS71773.1 - 1.7e-09 38.0 3.1 1.8e-05 25.0 0.3 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 RUS71773.1 - 2.4e-05 24.2 4.0 1.1 9.7 0.0 5.3 6 0 0 6 6 5 2 HEAT repeat B2-adapt-app_C PF09066.10 RUS71773.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain AP4E_app_platf PF14807.6 RUS71773.1 - 0.065 13.6 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF1186 PF06685.11 RUS71773.1 - 0.066 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) SDA1 PF05285.12 RUS71773.1 - 0.22 10.9 54.1 0.025 14.0 42.4 2.2 2 0 0 2 2 2 0 SDA1 HEAT_EZ PF13513.6 RUS71773.1 - 0.24 12.0 5.2 5 7.7 0.1 4.6 6 0 0 6 6 5 0 HEAT-like repeat Zip PF02535.22 RUS71773.1 - 0.38 9.9 6.6 0.41 9.8 4.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Macoilin PF09726.9 RUS71773.1 - 0.58 8.7 11.6 0.94 8.0 11.6 1.2 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 RUS71773.1 - 9.3 4.9 18.6 7.1 5.3 16.2 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SCAMP PF04144.13 RUS71774.1 - 2.4e-39 135.4 2.2 2.8e-39 135.2 2.2 1.1 1 0 0 1 1 1 1 SCAMP family Mlo PF03094.15 RUS71774.1 - 0.034 12.5 0.3 0.052 11.9 0.3 1.2 1 0 0 1 1 1 0 Mlo family OmpH PF03938.14 RUS71774.1 - 0.43 10.9 6.4 0.66 10.3 6.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) VirB3 PF05101.13 RUS71774.1 - 0.46 10.8 2.3 0.71 10.1 2.3 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF2681 PF10883.8 RUS71774.1 - 0.73 10.3 4.3 1.4 9.4 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Tmemb_55A PF09788.9 RUS71774.1 - 5.6 6.0 5.4 0.75 8.8 0.9 1.7 2 0 0 2 2 2 0 Transmembrane protein 55A Gemini_BL1 PF00845.19 RUS71775.1 - 0.011 15.4 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Geminivirus BL1 movement protein SNF PF00209.18 RUS71776.1 - 1.7e-204 680.4 33.8 3.8e-204 679.2 33.8 1.5 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DAO PF01266.24 RUS71778.1 - 7.2e-11 42.3 0.2 2.3e-10 40.6 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS71778.1 - 0.034 13.4 0.0 0.089 12.0 0.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS71778.1 - 0.055 14.0 1.0 0.26 11.9 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS71778.1 - 0.058 13.6 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HAUS4 PF14735.6 RUS71779.1 - 2.3e-56 191.1 7.0 2.3e-56 191.1 7.0 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 Phage_GP20 PF06810.11 RUS71779.1 - 0.013 15.3 0.2 0.013 15.3 0.2 2.4 3 0 0 3 3 3 0 Phage minor structural protein GP20 HsbA PF12296.8 RUS71779.1 - 0.095 13.1 2.8 0.34 11.3 1.1 2.6 2 1 0 2 2 2 0 Hydrophobic surface binding protein A YkyA PF10368.9 RUS71779.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.9 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Baculo_PEP_C PF04513.12 RUS71779.1 - 0.24 11.4 1.7 2 8.4 0.2 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 RUS71779.1 - 6.2 7.1 7.6 0.46 10.7 0.3 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RT_RNaseH_2 PF17919.1 RUS71780.1 - 9.7e-32 109.0 0.0 2.6e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS71780.1 - 1.3e-27 96.1 0.0 2.9e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS71780.1 - 1.1e-20 74.2 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS71780.1 - 3e-13 49.7 0.2 6.3e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS71780.1 - 1.8e-06 28.1 0.0 8.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 RUS71780.1 - 0.0054 17.0 0.6 0.024 14.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 RUS71780.1 - 0.0095 16.1 0.2 0.025 14.8 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Phage_int_SAM_1 PF02899.17 RUS71780.1 - 0.13 12.6 0.3 0.47 10.8 0.3 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ARF7EP_C PF14949.6 RUS71781.1 - 8.5e-31 106.7 7.2 8.5e-31 106.7 7.2 2.3 2 1 1 3 3 3 1 ARF7 effector protein C-terminus AvrM_N PF18247.1 RUS71781.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain ASCH PF04266.14 RUS71782.1 - 1.4e-17 64.2 0.0 2.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 RUS71782.1 - 1.8e-11 43.8 9.7 3.7e-11 42.8 9.7 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF3668 PF12416.8 RUS71785.1 - 7.2e-68 228.8 0.2 4e-67 226.4 0.0 2.3 2 0 0 2 2 2 1 Cep120 protein C2 PF00168.30 RUS71785.1 - 3.1e-07 30.6 0.1 0.052 13.8 0.0 3.4 3 0 0 3 3 3 2 C2 domain DUF4497 PF14924.6 RUS71785.1 - 0.00055 20.4 0.2 0.0056 17.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4497) Pkinase PF00069.25 RUS71786.1 - 1.3e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS71786.1 - 2.9e-15 56.2 0.0 3.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS71786.1 - 2.4e-08 33.2 0.5 3.4e-08 32.7 0.5 1.1 1 0 0 1 1 1 1 Fungal protein kinase CK1gamma_C PF12605.8 RUS71786.1 - 1.9e-06 28.9 6.4 1.9e-06 28.9 6.4 1.9 2 1 0 2 2 2 1 Casein kinase 1 gamma C terminal WD40 PF00400.32 RUS71787.1 - 2.5e-35 119.9 30.2 3.8e-08 33.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71787.1 - 3.9e-15 55.9 0.1 0.013 15.8 0.1 5.1 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS71787.1 - 8.3e-07 28.6 0.3 0.61 9.4 0.0 4.7 1 1 4 5 5 5 4 WD40-like domain Flg_hook PF02120.16 RUS71787.1 - 0.0024 17.7 0.1 0.027 14.3 0.1 2.1 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Ge1_WD40 PF16529.5 RUS71787.1 - 0.0044 16.0 0.3 34 3.2 0.1 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_8 PF13181.6 RUS71788.1 - 2.8e-10 39.6 0.8 0.00028 20.8 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS71788.1 - 1.2e-07 31.3 0.6 0.0066 16.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS71788.1 - 1.2e-07 31.9 0.2 2.8e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS71788.1 - 1.9e-06 27.4 1.2 0.049 13.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS71788.1 - 7.1e-05 22.6 0.1 0.03 14.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS71788.1 - 0.0014 18.4 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71788.1 - 0.023 15.3 0.2 0.26 12.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS71788.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 RUS71788.1 - 0.15 12.8 0.1 4.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4007 PF13182.6 RUS71789.1 - 0.019 14.1 0.5 0.027 13.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4007) PGBA_C PF15437.6 RUS71789.1 - 0.042 14.2 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Dynein_light PF01221.18 RUS71790.1 - 3.3e-43 145.9 1.5 4.7e-43 145.4 1.5 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 RE_LlaMI PF09562.10 RUS71790.1 - 0.04 13.5 1.0 0.049 13.2 1.0 1.1 1 0 0 1 1 1 0 LlaMI restriction endonuclease TPT PF03151.16 RUS71791.1 - 1.1e-20 74.1 15.2 2.5e-20 73.0 15.2 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family PS_pyruv_trans PF04230.13 RUS71791.1 - 2.2e-16 60.7 0.3 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase EamA PF00892.20 RUS71791.1 - 0.0077 16.4 6.0 0.0077 16.4 6.0 3.3 2 1 1 3 3 3 1 EamA-like transporter family ATP-synt_I PF03899.15 RUS71791.1 - 0.015 15.7 1.3 0.015 15.7 1.3 2.5 2 0 0 2 2 2 0 ATP synthase I chain DUF2178 PF09946.9 RUS71791.1 - 0.051 13.7 0.4 0.051 13.7 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) DUF2976 PF11190.8 RUS71791.1 - 0.38 10.6 2.3 9.6 6.1 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2976) START PF01852.19 RUS71795.1 - 7.2e-11 41.9 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 START domain Lectin_C PF00059.21 RUS71798.1 - 0.00015 22.4 0.9 0.25 12.1 0.2 2.1 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 RUS71798.1 - 0.036 13.7 1.6 2.3 7.8 0.1 2.0 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Fmp27 PF10344.9 RUS71799.1 - 0.0015 16.7 6.9 1 7.4 0.7 3.5 1 1 2 3 3 3 3 Mitochondrial protein from FMP27 DUF3564 PF12087.8 RUS71799.1 - 0.017 15.1 0.2 0.52 10.3 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3564) Urease_beta PF00699.20 RUS71799.1 - 0.038 14.0 0.2 14 5.8 0.0 3.3 1 1 3 4 4 4 0 Urease beta subunit MAR_sialic_bdg PF10564.9 RUS71799.1 - 0.11 12.6 5.1 7.4 6.7 0.1 3.2 1 1 3 4 4 4 0 Sialic-acid binding micronemal adhesive repeat Ank_2 PF12796.7 RUS71800.1 - 2.3e-44 149.9 3.5 3.2e-08 34.0 0.0 8.4 3 2 6 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS71800.1 - 3.4e-34 116.8 6.5 7.9e-05 23.1 0.0 10.1 6 1 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS71800.1 - 1.5e-29 98.7 8.1 0.0039 17.6 0.0 15.2 17 0 0 17 17 17 5 Ankyrin repeat Ank_5 PF13857.6 RUS71800.1 - 5e-26 90.4 17.5 0.002 18.4 0.2 10.1 8 3 2 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS71800.1 - 5.8e-24 83.4 7.2 0.0049 17.2 0.1 11.6 13 0 0 13 13 13 6 Ankyrin repeat Vinculin PF01044.19 RUS71800.1 - 0.0018 16.6 0.1 0.47 8.6 0.0 2.1 2 0 0 2 2 2 2 Vinculin family DUF4745 PF15923.5 RUS71800.1 - 0.0037 17.2 0.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4745) Cyclin PF08613.11 RUS71800.1 - 0.057 13.8 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Cyclin SOCS_box PF07525.16 RUS71800.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 SOCS box Trypsin PF00089.26 RUS71801.1 - 4.6e-49 167.2 0.6 6.9e-49 166.6 0.6 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS71801.1 - 8.8e-07 29.9 0.2 1.6e-06 29.1 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Lectin_C PF00059.21 RUS71801.1 - 0.0098 16.6 0.3 0.055 14.2 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain ERM PF00769.19 RUS71802.1 - 0.0091 15.8 5.7 0.01 15.7 5.7 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Loricrin PF15847.5 RUS71803.1 - 5.5e-06 25.7 47.2 0.33 10.0 6.7 4.2 1 1 3 4 4 4 4 Major keratinocyte cell envelope protein ANF_receptor PF01094.28 RUS71804.1 - 8.9e-33 113.8 0.0 1.5e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS71804.1 - 0.00028 20.7 1.1 0.13 11.9 0.1 2.3 2 0 0 2 2 2 2 Periplasmic binding protein AP3D1 PF06375.11 RUS71804.1 - 5.9 7.1 13.4 11 6.3 13.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ANF_receptor PF01094.28 RUS71805.1 - 8.3e-18 64.6 0.0 8.9e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DnaJ PF00226.31 RUS71806.1 - 1.5e-22 79.5 1.3 1.5e-22 79.5 1.3 1.6 2 0 0 2 2 2 1 DnaJ domain LMBR1 PF04791.16 RUS71806.1 - 0.052 12.4 1.5 0.1 11.5 1.5 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Phage_Gp23 PF10669.9 RUS71806.1 - 0.066 13.5 0.5 0.066 13.5 0.5 1.9 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) DNA_pol_phi PF04931.13 RUS71807.1 - 0.00049 18.4 32.5 0.00052 18.3 32.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 RUS71807.1 - 0.029 13.7 11.8 0.028 13.8 11.8 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 RUS71807.1 - 0.076 11.4 12.7 0.082 11.3 12.7 1.1 1 0 0 1 1 1 0 Mpp10 protein eIF-3c_N PF05470.12 RUS71807.1 - 0.68 8.2 4.4 0.71 8.1 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2796 PF10986.8 RUS71807.1 - 3 7.8 7.5 8.9 6.2 7.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) DUF4637 PF15470.6 RUS71807.1 - 8.7 6.0 8.2 14 5.3 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ribosomal_L19 PF01245.20 RUS71808.1 - 2.3e-16 59.7 0.0 3.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 C2 PF00168.30 RUS71809.1 - 1.3e-51 173.2 0.0 6.7e-25 87.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 RUS71809.1 - 0.0002 21.0 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.6 RUS71809.1 - 0.0024 17.7 0.2 0.92 9.3 0.1 2.4 1 1 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins DUF2627 PF11118.8 RUS71809.1 - 0.015 15.8 1.0 0.03 14.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF3776 PF12618.8 RUS71810.1 - 0.065 13.8 0.9 0.17 12.5 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) YIF1 PF03878.15 RUS71811.1 - 4.5e-88 294.8 4.7 5.8e-88 294.4 4.7 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 RUS71811.1 - 7.1e-05 22.6 12.1 9.8e-05 22.1 9.6 2.0 1 1 1 2 2 2 2 Yip1 domain Fibrinogen_C PF00147.18 RUS71812.1 - 7.5e-55 186.1 6.1 1.3e-54 185.3 6.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS71812.1 - 1.5e-08 34.7 10.4 3.9e-07 30.1 5.0 3.0 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS71812.1 - 0.0097 16.0 2.5 0.0097 16.0 2.5 4.1 1 1 3 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIIC_delta PF12657.7 RUS71812.1 - 0.042 13.8 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Lant_dehydr_C PF14028.6 RUS71812.1 - 0.044 13.3 2.2 3.8 7.0 0.3 2.3 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term PLC-beta_C PF08703.10 RUS71812.1 - 0.057 13.4 10.3 0.41 10.6 0.9 3.7 2 1 2 4 4 4 0 PLC-beta C terminal DUF4709 PF15821.5 RUS71812.1 - 0.22 11.8 12.9 0.28 11.5 1.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) KMP11 PF03037.16 RUS71812.1 - 0.22 12.3 6.3 4.8 8.0 6.3 2.6 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DFF40 PF09230.10 RUS71812.1 - 0.25 10.9 4.6 0.21 11.2 1.5 2.1 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa Syntaxin-6_N PF09177.11 RUS71812.1 - 0.26 11.9 9.1 9.3 6.9 0.1 4.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Nbl1_Borealin_N PF10444.9 RUS71812.1 - 0.56 9.9 6.8 0.38 10.4 1.2 3.3 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal T3SS_needle_F PF09392.10 RUS71812.1 - 0.64 10.3 5.2 14 6.0 0.1 4.5 2 2 3 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NPV_P10 PF05531.12 RUS71812.1 - 0.69 10.4 9.3 4.4e+02 1.4 9.3 4.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 RUS71812.1 - 0.8 9.2 14.1 0.63 9.6 7.8 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit YtxH PF12732.7 RUS71812.1 - 0.9 10.1 6.8 2 9.0 1.5 3.7 2 1 1 3 3 3 0 YtxH-like protein DUF4164 PF13747.6 RUS71812.1 - 1.1 9.6 16.2 3.5 8.0 2.6 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Spectrin PF00435.21 RUS71812.1 - 1.3 9.6 14.6 0.088 13.3 3.2 2.8 2 1 1 3 3 2 0 Spectrin repeat DUF5082 PF16888.5 RUS71812.1 - 1.3 9.3 12.5 28 5.0 7.6 4.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF883 PF05957.13 RUS71812.1 - 1.3 9.7 10.8 4.2 8.0 0.5 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) TINF2_N PF14973.6 RUS71812.1 - 2.1 8.7 4.6 0.93 9.8 1.2 2.2 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Fib_alpha PF08702.10 RUS71812.1 - 2.4 8.3 19.7 2.1 8.5 7.4 3.6 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Phage_Mu_Gam PF07352.12 RUS71812.1 - 2.7 7.9 9.1 2.2 8.2 0.4 3.2 3 1 1 4 4 3 0 Bacteriophage Mu Gam like protein Phasin PF05597.11 RUS71812.1 - 2.8 8.0 11.0 6.1 6.9 0.6 3.4 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Utp12 PF04003.12 RUS71812.1 - 3.6 7.9 5.2 1.9 8.9 0.2 3.0 3 1 0 4 4 3 0 Dip2/Utp12 Family OmpH PF03938.14 RUS71812.1 - 4.2 7.7 11.6 2 8.8 4.7 2.5 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) Carbpep_Y_N PF05388.11 RUS71812.1 - 7 7.2 11.5 1.5 9.4 1.2 3.3 1 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide DUF1664 PF07889.12 RUS71812.1 - 7.8 6.6 15.1 2.7 8.0 4.1 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 RUS71812.1 - 9.7 6.2 10.7 40 4.2 7.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) SRP9-21 PF05486.12 RUS71813.1 - 9.7e-15 54.7 0.4 4.9e-13 49.3 0.4 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WH1 PF00568.23 RUS71814.1 - 1.1e-34 118.6 0.0 1.7e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 RUS71814.1 - 0.00011 22.4 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain DCP1 PF06058.13 RUS71814.1 - 0.16 11.9 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family BCS1_N PF08740.11 RUS71815.1 - 3e-40 138.2 0.7 4.2e-40 137.7 0.7 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 RUS71815.1 - 2.7e-19 69.9 0.0 5.5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS71815.1 - 0.00041 20.4 0.0 0.0016 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RUS71815.1 - 0.00081 19.0 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS71815.1 - 0.0017 18.8 0.0 0.0049 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 RUS71815.1 - 0.006 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 RUS71815.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PPV_E1_C PF00519.17 RUS71815.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Rad17 PF03215.15 RUS71815.1 - 0.018 15.0 0.0 0.13 12.2 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 RUS71815.1 - 0.024 15.1 0.0 0.061 13.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 RUS71815.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RUS71815.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RUS71815.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 RUS71815.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 RUS71815.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 RUS71815.1 - 0.13 12.0 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RUS71815.1 - 0.14 12.7 0.0 0.61 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RUS71815.1 - 0.15 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RUS71815.1 - 0.17 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS71815.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_5 PF13857.6 RUS71816.1 - 2.4e-19 69.1 6.7 2.8e-10 40.2 1.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS71816.1 - 2.5e-18 65.6 0.6 3.8e-06 27.1 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RUS71816.1 - 5.9e-18 65.2 1.2 2.4e-10 40.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) BRCT_2 PF16589.5 RUS71816.1 - 1e-13 51.5 0.3 8.3e-07 29.3 0.0 3.4 3 1 0 3 3 2 2 BRCT domain, a BRCA1 C-terminus domain Ank_4 PF13637.6 RUS71816.1 - 1.4e-13 51.0 3.4 7.6e-09 35.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS71816.1 - 2e-12 46.1 0.2 2.7e-05 24.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat BRCT PF00533.26 RUS71816.1 - 2.1e-10 40.8 0.0 3.5e-06 27.3 0.1 3.5 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-RING_6 PF14835.6 RUS71816.1 - 5.6e-07 29.4 3.0 1.7e-06 27.8 3.0 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RTT107_BRCT_5 PF16770.5 RUS71816.1 - 7.3e-05 22.6 0.1 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_5 PF14634.6 RUS71816.1 - 0.009 16.0 12.7 0.009 16.0 12.7 2.2 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS71816.1 - 0.065 13.1 11.2 0.23 11.3 11.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS71816.1 - 0.14 12.2 7.3 0.47 10.5 5.4 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS71816.1 - 0.2 11.5 12.2 0.82 9.6 12.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS71816.1 - 0.31 11.4 12.9 1.1 9.6 12.9 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 RUS71816.1 - 0.8 9.9 8.3 3.1 8.0 5.8 3.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RUS71816.1 - 1.1 9.6 8.7 3.3 8.1 8.7 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS71816.1 - 3.3 7.7 15.3 4.6 7.2 12.2 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 RUS71817.1 - 5.6e-34 115.6 29.0 0.0051 17.6 3.9 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS71817.1 - 2.5e-05 24.5 3.3 0.6 10.4 0.0 6.4 5 3 4 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain zf-CCCH PF00642.24 RUS71818.1 - 0.00041 20.2 0.3 0.0074 16.2 0.1 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS71818.1 - 0.024 14.7 1.1 0.11 12.6 0.1 2.6 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 RUS71818.1 - 0.17 12.4 1.0 0.59 10.7 1.0 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HTH_45 PF14947.6 RUS71819.1 - 0.058 13.4 0.6 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix Sushi PF00084.20 RUS71820.1 - 5e-19 68.7 14.4 6.2e-06 26.7 0.1 5.0 4 1 0 4 4 4 4 Sushi repeat (SCR repeat) MANEC PF07502.14 RUS71820.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.4 3 0 0 3 3 3 0 MANEC domain NARP1 PF12569.8 RUS71826.1 - 0.00072 18.6 17.9 0.00078 18.5 17.9 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF1682 PF07946.14 RUS71826.1 - 0.0074 15.5 20.6 0.011 15.0 20.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) FPN1 PF06963.12 RUS71826.1 - 0.01 14.4 1.0 0.018 13.6 1.0 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) CLN3 PF02487.17 RUS71826.1 - 0.021 13.9 1.8 0.029 13.4 1.8 1.1 1 0 0 1 1 1 0 CLN3 protein TFB6 PF17110.5 RUS71826.1 - 0.025 14.4 1.8 0.034 13.9 1.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF5308 PF17233.2 RUS71826.1 - 0.035 14.4 0.8 0.047 13.9 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) RR_TM4-6 PF06459.12 RUS71826.1 - 0.04 13.7 14.6 0.051 13.4 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 RUS71826.1 - 0.041 13.8 3.5 0.054 13.4 3.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein RPOL_N PF14700.6 RUS71826.1 - 0.043 13.2 16.6 0.08 12.3 16.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RNA_pol_Rpc4 PF05132.14 RUS71826.1 - 0.045 14.2 12.7 0.064 13.7 12.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Lys-AminoMut_A PF09043.11 RUS71826.1 - 0.05 12.1 5.0 0.079 11.4 5.0 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DDHD PF02862.17 RUS71826.1 - 0.073 13.2 6.6 0.095 12.8 6.6 1.1 1 0 0 1 1 1 0 DDHD domain Paramyxo_ncap PF00973.19 RUS71826.1 - 0.08 11.9 8.1 0.11 11.4 8.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Connexin PF00029.19 RUS71826.1 - 0.1 12.3 16.3 0.22 11.3 16.3 1.5 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 RUS71826.1 - 0.19 10.7 7.6 0.26 10.2 7.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 RUS71826.1 - 0.26 12.3 8.5 0.44 11.5 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SspB PF04386.13 RUS71826.1 - 0.28 11.1 7.6 0.36 10.7 7.6 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DUF3405 PF11885.8 RUS71826.1 - 0.36 9.4 10.0 0.44 9.1 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) RPN2_C PF18004.1 RUS71826.1 - 0.48 10.3 27.8 0.65 9.9 27.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2828 PF11443.8 RUS71826.1 - 0.49 8.4 21.7 0.66 8.0 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Folate_carrier PF01770.18 RUS71826.1 - 0.52 9.0 5.6 0.71 8.5 5.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF3807 PF12720.7 RUS71826.1 - 0.67 10.2 21.4 0.92 9.8 21.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SpoIIP PF07454.11 RUS71826.1 - 0.75 9.2 15.9 0.97 8.8 15.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AIF_C PF14721.6 RUS71826.1 - 0.87 9.9 11.8 1.3 9.4 11.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.14 RUS71826.1 - 1 9.1 12.7 1.5 8.5 12.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Vfa1 PF08432.10 RUS71826.1 - 1.1 9.6 30.0 1.6 9.0 30.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LicD PF04991.13 RUS71826.1 - 1.7 8.7 17.0 2.5 8.2 17.0 1.2 1 0 0 1 1 1 0 LicD family PPL5 PF18168.1 RUS71826.1 - 2 7.6 17.0 2.9 7.1 17.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SRP-alpha_N PF04086.13 RUS71826.1 - 2.3 8.0 27.5 3.1 7.7 27.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4228 PF14009.6 RUS71826.1 - 2.5 8.4 10.6 3.6 7.9 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF3482 PF11981.8 RUS71826.1 - 2.5 7.4 6.5 3.5 6.9 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Tim54 PF11711.8 RUS71826.1 - 2.7 6.7 18.8 3.7 6.2 18.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rxt3 PF08642.10 RUS71826.1 - 2.7 8.8 7.7 4.5 8.1 7.7 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Pex24p PF06398.11 RUS71826.1 - 2.9 6.8 7.3 3.3 6.6 7.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Band_3_cyto PF07565.13 RUS71826.1 - 4.1 7.1 8.4 5.2 6.8 8.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Coilin_N PF15862.5 RUS71826.1 - 4.8 7.0 31.6 9.9 6.0 31.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus GNAT_acetyltr_2 PF13718.6 RUS71826.1 - 5.5 6.3 9.8 8.4 5.7 9.8 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PcfK PF14058.6 RUS71826.1 - 5.8 7.2 28.4 8.7 6.6 28.4 1.3 1 0 0 1 1 1 0 PcfK-like protein Miga PF10265.9 RUS71826.1 - 6.2 5.7 16.0 8.1 5.3 16.0 1.1 1 0 0 1 1 1 0 Mitoguardin Zip PF02535.22 RUS71826.1 - 6.9 5.8 8.3 10 5.3 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 RUS71826.1 - 6.9 6.3 12.6 0.32 10.6 6.7 1.8 2 0 0 2 2 2 0 FAM176 family NPR3 PF03666.13 RUS71826.1 - 7.9 5.2 19.9 10 4.8 19.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_L18 PF17135.4 RUS71827.1 - 3.6e-95 316.7 3.8 3.9e-95 316.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 RUS71827.1 - 0.0013 19.4 0.2 0.0053 17.4 0.2 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DAGK_cat PF00781.24 RUS71828.1 - 1.4e-22 79.7 0.0 2.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SPARC_Ca_bdg PF10591.9 RUS71829.1 - 1.7e-20 73.4 9.5 1.7e-20 73.4 9.5 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 RUS71829.1 - 5.4e-12 45.2 6.9 5.6e-12 45.1 3.0 2.8 1 1 0 2 2 2 1 Thyroglobulin type-1 repeat EF-hand_1 PF00036.32 RUS71829.1 - 0.0034 16.8 0.0 0.77 9.5 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS71829.1 - 0.013 15.4 0.2 3.6 7.8 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain PepSY_2 PF13670.6 RUS71829.1 - 0.018 15.0 0.2 0.098 12.7 0.0 2.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain EF-hand_7 PF13499.6 RUS71829.1 - 0.07 13.6 2.2 0.42 11.1 0.8 2.8 2 1 1 3 3 3 0 EF-hand domain pair Alpha_kinase PF02816.18 RUS71830.1 - 1.6e-59 201.2 0.1 2.8e-59 200.4 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 RUS71830.1 - 0.22 12.3 2.0 46 4.9 0.4 3.6 4 0 0 4 4 4 0 Sel1 repeat SNAP PF14938.6 RUS71830.1 - 0.45 9.9 3.4 0.55 9.6 0.9 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Ank_2 PF12796.7 RUS71831.1 - 3.5e-15 56.3 0.0 2e-07 31.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS71831.1 - 1.9e-10 40.0 0.5 0.056 14.0 0.0 5.8 8 0 0 8 8 8 2 Ankyrin repeat SOCS_box PF07525.16 RUS71831.1 - 7.2e-10 39.1 2.1 1.8e-09 37.8 2.1 1.7 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 RUS71831.1 - 2.2e-09 37.7 0.0 0.0041 17.7 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS71831.1 - 3.5e-09 36.7 0.1 0.052 14.0 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 RUS71831.1 - 3.5e-08 33.6 0.0 0.002 18.4 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ras PF00071.22 RUS71832.1 - 6e-41 139.8 0.0 6.9e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS71832.1 - 3.4e-21 75.7 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS71832.1 - 8.9e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS71832.1 - 2.9e-05 23.7 0.0 6.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS71832.1 - 0.0015 18.5 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 RUS71832.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 RUS71832.1 - 0.0019 18.2 0.0 0.0045 17.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RUS71832.1 - 0.0094 15.8 0.2 0.029 14.2 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DRMBL PF07522.14 RUS71833.1 - 1.4e-29 102.5 0.0 3.4e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 RUS71833.1 - 8.9e-07 28.6 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RUS71833.1 - 0.0019 18.3 0.1 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily CCSAP PF15748.5 RUS71834.1 - 0.0043 17.2 13.4 0.0063 16.7 13.4 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DDHD PF02862.17 RUS71834.1 - 0.0068 16.6 0.4 0.0072 16.5 0.4 1.2 1 0 0 1 1 1 1 DDHD domain Plasmodium_Vir PF05795.11 RUS71834.1 - 0.013 14.9 10.2 0.016 14.7 10.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIF_alpha PF05793.12 RUS71834.1 - 0.018 13.7 59.2 0.023 13.3 59.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4045 PF13254.6 RUS71834.1 - 0.018 14.7 7.2 0.021 14.5 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 RUS71834.1 - 0.073 11.8 14.1 0.089 11.5 14.1 1.1 1 0 0 1 1 1 0 Presenilin Dynamin_N PF00350.23 RUS71834.1 - 0.11 12.6 1.4 0.12 12.5 1.4 1.2 1 0 0 1 1 1 0 Dynamin family DUF5308 PF17233.2 RUS71834.1 - 0.11 12.7 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Sec62 PF03839.16 RUS71834.1 - 0.34 10.4 9.6 0.44 10.0 9.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 AAR2 PF05282.11 RUS71834.1 - 0.34 10.2 5.7 0.45 9.9 5.7 1.2 1 0 0 1 1 1 0 AAR2 protein FAM60A PF15396.6 RUS71834.1 - 0.54 10.2 7.0 0.86 9.6 7.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.8 RUS71834.1 - 0.57 10.2 6.8 0.82 9.7 6.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Mpp10 PF04006.12 RUS71834.1 - 1 7.8 51.0 1.5 7.2 51.0 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF4628 PF15429.6 RUS71834.1 - 1.1 8.9 12.9 1.6 8.4 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) SLC12 PF03522.15 RUS71834.1 - 1.1 8.2 11.5 1.4 7.9 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 RUS71834.1 - 1.3 7.9 9.0 1.4 7.7 9.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SID-1_RNA_chan PF13965.6 RUS71834.1 - 1.6 7.1 4.8 1.9 6.8 4.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 RUS71834.1 - 2.1 7.2 5.2 2.3 7.1 5.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NPR3 PF03666.13 RUS71834.1 - 3.4 6.4 21.7 4.3 6.0 21.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MFAP1 PF06991.11 RUS71834.1 - 3.4 7.5 36.1 5.5 6.8 36.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing AAA_11 PF13086.6 RUS71834.1 - 3.5 7.4 8.3 4.3 7.1 8.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 RUS71834.1 - 3.5 6.1 12.0 4 5.9 12.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FGF-BP1 PF06473.12 RUS71834.1 - 5.2 6.8 14.2 7 6.4 14.2 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SURF2 PF05477.11 RUS71834.1 - 7.3 6.2 27.5 11 5.6 27.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Smg8_Smg9 PF10220.9 RUS71834.1 - 7.5 4.7 12.4 8.9 4.5 12.4 1.0 1 0 0 1 1 1 0 Smg8_Smg9 zf-nanos PF05741.13 RUS71835.1 - 1.4e-23 82.9 6.4 2.3e-23 82.2 6.4 1.3 1 0 0 1 1 1 1 Nanos RNA binding domain HBM PF16591.5 RUS71835.1 - 0.022 14.2 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain zf-HIT PF04438.16 RUS71835.1 - 0.77 9.7 15.3 0.31 11.0 4.9 2.6 3 0 0 3 3 3 0 HIT zinc finger PQQ_2 PF13360.6 RUS71836.1 - 0.002 17.7 0.3 0.011 15.4 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain RhoGAP PF00620.27 RUS71837.1 - 2.2e-47 160.7 0.0 3.6e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.6 RUS71837.1 - 2.4e-10 40.8 0.1 5.6e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_9 PF14604.6 RUS71837.1 - 3.8e-10 39.5 0.7 7.1e-10 38.6 0.7 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 RUS71837.1 - 2.5e-09 37.6 0.1 1.1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 RUS71837.1 - 3.4e-07 29.8 1.2 7.4e-07 28.7 1.2 1.6 1 0 0 1 1 1 1 SH3 domain WW PF00397.26 RUS71837.1 - 0.00025 21.0 0.7 0.023 14.8 0.1 3.0 2 0 0 2 2 2 1 WW domain RPEL PF02755.15 RUS71837.1 - 0.0049 16.5 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 RPEL repeat PH_11 PF15413.6 RUS71837.1 - 0.013 15.9 0.4 0.049 14.1 0.4 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain SH3_10 PF17902.1 RUS71837.1 - 0.025 14.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.17 RUS71837.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain p450 PF00067.22 RUS71838.1 - 6.5e-36 124.1 0.8 7.7e-36 123.8 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 NOA36 PF06524.12 RUS71839.1 - 0.15 11.3 33.5 0.25 10.7 33.5 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 RUS71839.1 - 0.36 9.0 23.5 0.54 8.4 23.5 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 RUS71839.1 - 1 8.9 17.4 1.6 8.3 17.4 1.3 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 RUS71839.1 - 3.6 6.9 25.3 7.4 5.9 25.3 1.5 1 0 0 1 1 1 0 SDA1 Ribosomal_L7Ae PF01248.26 RUS71840.1 - 5.9e-09 35.5 0.2 1e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1848 PF08902.11 RUS71840.1 - 0.026 14.2 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Dishevelled PF02377.15 RUS71841.1 - 0.0049 17.3 12.4 0.019 15.4 4.2 2.4 2 0 0 2 2 2 2 Dishevelled specific domain SPT6_acidic PF14632.6 RUS71841.1 - 0.47 11.1 8.6 0.83 10.3 1.3 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SR-25 PF10500.9 RUS71841.1 - 0.9 9.1 13.4 0.31 10.6 4.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FXR_C1 PF16096.5 RUS71841.1 - 1.6 9.0 16.3 0.97 9.7 2.9 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Rrn6 PF10214.9 RUS71841.1 - 7.6 4.9 9.9 4.8 5.6 3.7 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DUF1953 PF09196.10 RUS71842.1 - 0.068 13.0 4.1 14 5.6 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF1953) 7tm_1 PF00001.21 RUS71843.1 - 3.7e-22 78.9 5.8 4.5e-22 78.6 5.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PIG-F PF06699.11 RUS71843.1 - 0.0028 17.8 2.4 0.0083 16.3 0.6 2.1 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F Phage_holin_3_6 PF07332.11 RUS71843.1 - 0.12 12.4 2.2 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SPECT1 PF18680.1 RUS71844.1 - 0.31 10.7 10.2 16 5.1 1.2 3.6 1 1 2 3 3 3 0 Plasmodium host cell traversal SPECT1 GAF_3 PF13492.6 RUS71845.1 - 0.27 11.6 7.4 36 4.7 1.7 3.8 1 1 1 2 2 2 0 GAF domain Caudo_TAP PF02413.17 RUS71845.1 - 1.2 9.2 41.2 1.8e+04 -24.4 41.2 5.3 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Alfin PF12165.8 RUS71845.1 - 2.1 8.0 9.4 38 4.0 0.2 3.6 1 1 2 4 4 4 0 Alfin Adenylsucc_synt PF00709.21 RUS71845.1 - 4.9 6.0 25.4 7.6 5.3 8.6 2.4 1 1 1 2 2 2 0 Adenylosuccinate synthetase Cu_amine_oxid PF01179.20 RUS71846.1 - 2.3e-105 352.9 0.4 2.9e-105 352.6 0.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 RUS71846.1 - 2.1e-08 34.3 0.0 4.3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 RUS71846.1 - 0.00022 20.9 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN3 PF02728.16 RUS71846.1 - 0.001 19.4 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Spatacsin_C PF14649.6 RUS71847.1 - 1.6e-94 316.4 4.8 3.3e-94 315.4 4.8 1.5 1 0 0 1 1 1 1 Spatacsin C-terminus Pkinase PF00069.25 RUS71848.1 - 2.6e-05 23.7 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain COX7C PF02935.16 RUS71848.1 - 0.14 12.5 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc ThiF PF00899.21 RUS71849.1 - 6.1e-31 107.6 0.0 7.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 RUS71849.1 - 0.0045 16.6 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 RUS71849.1 - 0.0061 15.9 0.3 0.0076 15.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 RUS71849.1 - 0.032 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Csm1_N PF18504.1 RUS71849.1 - 0.038 14.3 0.3 0.16 12.3 0.2 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain ApbA PF02558.16 RUS71849.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DivIC PF04977.15 RUS71849.1 - 0.12 12.2 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator DAO PF01266.24 RUS71849.1 - 0.13 11.8 1.8 0.19 11.3 1.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2OG-FeII_Oxy_3 PF13640.6 RUS71850.1 - 4.3e-21 75.6 0.6 1.7e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 RUS71850.1 - 9.1e-12 45.5 0.0 2.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 RUS71850.1 - 1.4e-10 41.1 8.9 1.4e-10 41.1 8.9 2.1 2 0 0 2 2 2 1 MYND finger RecR PF02132.15 RUS71850.1 - 0.054 13.1 0.4 0.16 11.6 0.4 1.8 1 0 0 1 1 1 0 RecR protein FAM177 PF14774.6 RUS71851.1 - 1.5e-34 118.9 0.0 2.1e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 FAM177 family VWD PF00094.25 RUS71852.1 - 1.9e-23 83.5 1.0 8e-23 81.4 1.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type D domain Mucin2_WxxW PF13330.6 RUS71852.1 - 3.7e-12 46.9 1.0 3.7e-12 46.9 1.0 7.1 5 2 1 6 6 6 1 Mucin-2 protein WxxW repeating region Peptidase_M2 PF01401.18 RUS71852.1 - 5.1e-08 32.0 18.4 7.4e-07 28.2 0.0 2.3 1 1 1 2 2 2 1 Angiotensin-converting enzyme TIL PF01826.17 RUS71852.1 - 9.6e-06 25.8 14.4 9.6e-06 25.8 14.4 6.1 5 1 0 5 5 5 1 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 RUS71852.1 - 2.8e-05 23.9 18.2 0.00062 19.6 3.0 5.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like Hist_deacetyl PF00850.19 RUS71853.1 - 4.4e-83 279.3 0.1 5.4e-83 279.0 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 RUS71854.1 - 9.6e-13 47.8 0.8 9.6e-13 47.8 0.8 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS71854.1 - 1.6e-10 40.6 0.9 1.6e-10 40.6 0.9 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 RUS71854.1 - 4e-05 23.9 18.6 0.7 10.4 0.2 5.3 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS71854.1 - 0.00047 19.9 11.7 0.094 12.5 0.1 4.7 4 1 0 4 4 4 2 Leucine rich repeat FNIP PF05725.12 RUS71854.1 - 0.093 12.9 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 FNIP Repeat LRR_6 PF13516.6 RUS71854.1 - 0.28 11.3 13.3 0.29 11.3 0.6 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 RUS71854.1 - 1.2 10.0 11.1 41 5.3 0.3 6.0 5 2 1 6 6 6 0 Leucine Rich Repeat PKD_channel PF08016.12 RUS71855.1 - 2.8e-06 26.3 11.6 2.8e-06 26.3 11.6 1.9 2 1 1 3 3 3 1 Polycystin cation channel Ion_trans PF00520.31 RUS71855.1 - 5.6e-06 25.8 17.9 5.6e-06 25.8 17.9 1.8 2 0 0 2 2 2 1 Ion transport protein PET PF06297.14 RUS71856.1 - 0.019 15.2 0.2 0.034 14.5 0.2 1.5 1 0 0 1 1 1 0 PET Domain LIM PF00412.22 RUS71857.1 - 2e-09 37.5 5.9 2.1e-09 37.4 5.3 1.4 1 1 0 1 1 1 1 LIM domain zf-FLZ PF04570.14 RUS71857.1 - 0.07 12.6 6.0 0.82 9.2 3.6 2.3 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 RUS71857.1 - 7.6 6.7 14.0 1.6 8.9 0.2 3.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Hydrolase_4 PF12146.8 RUS71858.1 - 3.4e-70 236.0 0.0 4.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS71858.1 - 5.9e-16 58.9 0.5 7.9e-14 51.9 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS71858.1 - 4e-11 43.9 0.0 5.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RUS71858.1 - 1.9e-07 30.8 0.1 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RUS71858.1 - 4.9e-05 23.1 0.0 7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 RUS71858.1 - 0.00033 19.7 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 RUS71858.1 - 0.00051 19.9 0.4 0.51 10.1 0.0 2.6 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 RUS71858.1 - 0.00081 19.0 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.25 RUS71858.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 RUS71858.1 - 0.0036 17.1 0.0 0.045 13.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 RUS71858.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 RUS71858.1 - 0.056 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LIP PF03583.14 RUS71858.1 - 0.068 12.5 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase PGAP1 PF07819.13 RUS71858.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 RUS71858.1 - 0.14 12.0 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 RUS71858.1 - 0.15 11.7 0.0 3.2 7.3 0.0 2.7 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 RUS71858.1 - 0.18 11.9 0.3 0.43 10.7 0.3 1.6 1 1 0 1 1 1 0 Thioesterase domain DAGK_cat PF00781.24 RUS71859.1 - 2.6e-26 91.7 0.0 4.1e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 RUS71859.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase Peptidase_S9 PF00326.21 RUS71860.1 - 6.6e-37 127.0 0.0 9.8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RUS71860.1 - 2e-11 43.6 0.0 3.9e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS71860.1 - 6.8e-08 32.5 0.4 0.00015 21.5 0.6 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 RUS71860.1 - 1.2e-05 25.0 0.0 3.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RUS71860.1 - 3.7e-05 24.4 1.0 0.0012 19.5 1.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RUS71860.1 - 0.0012 18.8 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 RUS71860.1 - 0.0013 18.3 0.0 0.4 10.2 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 RUS71860.1 - 0.0077 16.1 0.1 0.044 13.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 RUS71860.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 SIS_2 PF13580.6 RUS71860.1 - 0.029 14.4 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 SIS domain AXE1 PF05448.12 RUS71860.1 - 0.079 11.6 0.0 2.1 6.9 0.0 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.9 RUS71860.1 - 0.2 10.3 0.0 0.38 9.4 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein TPR_1 PF00515.28 RUS71861.1 - 0.00011 21.8 0.1 0.00029 20.5 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS71861.1 - 0.00017 21.4 0.1 0.00035 20.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS71861.1 - 0.016 14.9 0.0 0.052 13.2 0.0 1.9 1 1 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 RUS71861.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 RUS71861.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-BED PF02892.15 RUS71862.1 - 4.9e-43 144.9 81.9 8.5e-06 25.7 2.7 9.7 10 0 0 10 10 9 9 BED zinc finger BIR PF00653.21 RUS71862.1 - 2.9e-11 43.9 19.7 1.8 9.2 0.1 9.1 9 0 0 9 9 9 4 Inhibitor of Apoptosis domain zf-C2H2_2 PF12756.7 RUS71862.1 - 2.9e-09 37.2 37.5 0.099 13.0 0.9 9.3 9 0 0 9 9 9 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RUS71862.1 - 2e-06 28.2 73.4 0.26 12.2 1.0 10.0 9 0 0 9 9 9 6 C2H2-type zinc finger PyrI_C PF02748.15 RUS71862.1 - 4e-05 23.4 18.8 20 5.2 0.1 8.4 8 0 0 8 8 8 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2197 PF09963.9 RUS71862.1 - 0.0029 17.8 26.4 1.7 9.0 0.1 8.7 9 0 0 9 9 9 2 Uncharacterized protein conserved in bacteria (DUF2197) DUF4838 PF16126.5 RUS71862.1 - 0.004 16.6 11.0 9 5.6 0.0 6.9 7 1 1 8 8 8 1 Domain of unknown function (DUF4838) FLILHELTA PF10306.9 RUS71862.1 - 0.012 16.0 0.3 86 3.6 0.0 5.1 6 0 0 6 6 5 0 Hypothetical protein FLILHELTA DUF4674 PF15719.5 RUS71862.1 - 0.024 14.7 88.5 0.29 11.1 0.7 9.2 6 3 3 9 9 9 0 Domain of unknown function (DUF4674) DUF3939 PF13075.6 RUS71862.1 - 0.044 13.8 0.5 18 5.3 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3939) DUF3896 PF13035.6 RUS71862.1 - 0.13 12.4 1.5 16 5.8 0.2 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) CxC7 PF18866.1 RUS71862.1 - 0.13 12.4 11.0 0.53 10.5 0.0 6.2 8 0 0 8 8 8 0 CxC7 like cysteine cluster associated with KDZ transposases Elf1 PF05129.13 RUS71862.1 - 0.17 12.0 24.3 21 5.3 0.0 9.2 11 0 0 11 11 11 0 Transcription elongation factor Elf1 like DUF5083 PF16890.5 RUS71862.1 - 0.19 11.5 0.6 52 3.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5083) zf-C2H2_12 PF18658.1 RUS71862.1 - 0.21 11.2 36.2 1.8 8.2 0.4 7.7 8 0 0 8 8 8 0 Zinc-finger C2H2-type zf-Di19 PF05605.12 RUS71862.1 - 0.29 11.4 39.9 5.8 7.3 0.4 9.3 9 0 0 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding T4-Gluco-transf PF09198.10 RUS71862.1 - 2.1 8.0 10.0 51 3.6 0.1 4.9 5 0 0 5 5 5 0 Bacteriophage T4 beta-glucosyltransferase DUF2947 PF11163.8 RUS71862.1 - 3.4 7.5 7.1 2.7 7.9 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2947) zf-U11-48K PF05253.12 RUS71863.1 - 3.4e-14 52.3 11.0 3.4e-07 30.0 1.7 2.7 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger VHS PF00790.19 RUS71864.1 - 1.1e-39 135.5 0.0 1e-38 132.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 RUS71864.1 - 3.5e-16 58.5 0.1 8e-16 57.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS71864.1 - 1.2e-12 47.3 0.0 2.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS71864.1 - 4e-11 42.6 0.2 1.3e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.20 RUS71864.1 - 7.8e-05 22.3 1.7 0.00016 21.3 1.7 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Sigma54_CBD PF04963.13 RUS71864.1 - 0.0054 16.6 0.0 0.024 14.5 0.1 2.0 3 0 0 3 3 3 1 Sigma-54 factor, core binding domain GAT PF03127.14 RUS71864.1 - 0.4 11.0 1.8 0.88 9.9 1.2 1.9 2 0 0 2 2 2 0 GAT domain TMF_TATA_bd PF12325.8 RUS71864.1 - 6.8 6.9 6.8 26 5.1 4.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mito_carr PF00153.27 RUS71865.1 - 1.7e-50 168.9 9.2 5.3e-21 74.4 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SpoVAB PF13782.6 RUS71865.1 - 0.00098 19.4 1.8 0.25 11.7 0.1 3.0 1 1 2 3 3 3 2 Stage V sporulation protein AB Serine_protease PF18405.1 RUS71865.1 - 0.0013 17.9 0.4 0.0013 17.9 0.4 2.3 2 2 0 2 2 2 1 Gammaproteobacterial serine protease DctQ PF04290.12 RUS71867.1 - 0.027 14.4 0.3 0.027 14.4 0.3 2.7 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Rod-binding PF10135.9 RUS71867.1 - 0.43 11.2 1.6 0.54 10.9 0.4 1.8 2 0 0 2 2 2 0 Rod binding protein Shisa PF13908.6 RUS71867.1 - 1.7 8.8 7.6 9.5 6.4 0.5 3.1 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator Sdh_cyt PF01127.22 RUS71867.1 - 5.7 7.0 6.7 32 4.6 0.1 2.9 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PMT_4TMC PF16192.5 RUS71868.1 - 1.6e-24 86.6 14.1 1.8e-24 86.5 14.1 1.0 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase DUF2370 PF10176.9 RUS71869.1 - 3.5e-08 33.4 0.1 5.6e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) Colicin_V PF02674.16 RUS71869.1 - 0.0045 17.0 1.2 0.0057 16.6 1.2 1.1 1 0 0 1 1 1 1 Colicin V production protein DUF1189 PF06691.11 RUS71869.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Comm PF15957.5 RUS71869.1 - 0.26 11.7 0.1 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 Commissureless PCAF_N PF06466.11 RUS71870.1 - 1.9e-117 391.2 2.3 2.9e-117 390.7 2.3 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_1 PF00583.25 RUS71870.1 - 8e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS71870.1 - 9.4e-06 25.6 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS71870.1 - 2e-05 24.9 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec20 PF03908.13 RUS71870.1 - 0.022 14.6 0.3 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 Sec20 BolA PF01722.18 RUS71871.1 - 1.6e-28 98.8 0.9 2.1e-28 98.4 0.9 1.2 1 0 0 1 1 1 1 BolA-like protein pP_pnuc_2 PF18166.1 RUS71871.1 - 0.074 13.1 0.1 0.21 11.6 0.1 1.7 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease DUF2420 PF10336.9 RUS71872.1 - 0.2 11.7 1.1 6.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2420) HLH PF00010.26 RUS71876.1 - 0.00034 20.5 0.1 0.0013 18.7 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Pox_D5 PF03288.16 RUS71879.1 - 0.016 15.6 0.1 0.056 13.9 0.1 1.9 1 0 0 1 1 1 0 Poxvirus D5 protein-like zf-U1 PF06220.12 RUS71881.1 - 8.2e-22 76.7 8.5 1.1e-21 76.3 8.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 RUS71881.1 - 0.55 10.7 4.8 5 7.7 4.8 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS71881.1 - 2.4 8.5 10.7 24 5.4 10.7 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EB PF01683.18 RUS71883.1 - 0.039 14.3 2.3 0.039 14.3 2.3 1.6 2 0 0 2 2 2 0 EB module EB PF01683.18 RUS71884.1 - 0.0056 16.9 7.5 0.012 15.9 7.5 1.6 1 0 0 1 1 1 1 EB module RT_RNaseH_2 PF17919.1 RUS71885.1 - 1.2e-34 118.3 0.0 1.9e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS71885.1 - 4.1e-31 107.4 0.0 7e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS71885.1 - 5.5e-10 39.5 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ig_3 PF13927.6 RUS71886.1 - 1.3e-07 32.1 0.9 0.00057 20.4 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS71886.1 - 2.1e-06 27.7 0.3 0.00072 19.6 0.0 2.8 1 1 2 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 RUS71886.1 - 4.8e-06 26.6 0.1 0.0022 18.1 0.0 2.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS71886.1 - 0.00021 21.6 0.1 0.008 16.5 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain S-layer PF07752.11 RUS71886.1 - 0.0045 16.1 0.5 0.0064 15.6 0.5 1.2 1 0 0 1 1 1 1 S-layer protein V-set PF07686.17 RUS71886.1 - 0.0068 16.6 1.0 0.086 13.0 1.0 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain ODV-E18 PF10717.9 RUS71886.1 - 0.051 13.5 0.6 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Guanylate_kin PF00625.21 RUS71889.1 - 1.7e-47 161.4 0.0 2.8e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 RUS71889.1 - 2.3e-08 34.3 0.1 5.3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 RUS71889.1 - 5.1e-08 32.5 0.0 1.5e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RUS71889.1 - 6.1e-06 25.8 0.1 1.5e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 RUS71889.1 - 3.6e-05 23.5 0.2 0.00013 21.7 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS71889.1 - 0.00053 20.3 0.1 0.0013 19.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 RUS71889.1 - 0.00055 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.6 RUS71889.1 - 0.071 13.1 0.0 0.51 10.3 0.0 2.4 2 1 0 2 2 2 0 Tricorn protease PDZ domain MMR_HSR1 PF01926.23 RUS71889.1 - 0.11 12.6 0.1 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gamma-thionin PF00304.20 RUS71890.1 - 0.18 12.1 9.2 0.072 13.4 4.6 2.1 1 1 1 2 2 2 0 Gamma-thionin family EGF_alliinase PF04863.13 RUS71890.1 - 6.2 7.3 8.9 2.2 8.8 5.9 1.8 2 1 0 2 2 2 0 Alliinase EGF-like domain C1q PF00386.21 RUS71893.1 - 1.2e-27 96.6 0.6 1.5e-27 96.3 0.6 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 RUS71893.1 - 0.0071 16.3 0.2 0.01 15.8 0.2 1.2 1 0 0 1 1 1 1 BclA C-terminal domain C1q PF00386.21 RUS71894.1 - 7.7e-29 100.5 0.8 8.9e-29 100.3 0.8 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 RUS71894.1 - 0.061 13.2 0.2 0.084 12.8 0.2 1.2 1 0 0 1 1 1 0 BclA C-terminal domain 7tm_1 PF00001.21 RUS71895.1 - 1.2e-08 34.6 17.2 1.2e-08 34.6 17.2 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS71895.1 - 0.00013 21.7 17.5 0.00026 20.7 17.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx wnt PF00110.19 RUS71896.1 - 8.7e-93 311.3 24.2 1e-92 311.1 24.2 1.0 1 0 0 1 1 1 1 wnt family Acetyltransf_1 PF00583.25 RUS71897.1 - 0.029 14.6 0.0 0.032 14.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SBF2 PF12335.8 RUS71898.1 - 3.3e-97 324.6 0.1 7.9e-97 323.4 0.1 1.6 1 0 0 1 1 1 1 Myotubularin protein Myotub-related PF06602.14 RUS71898.1 - 3.1e-94 315.8 0.0 8.5e-59 199.3 0.0 2.5 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain DENN PF02141.21 RUS71898.1 - 3.1e-49 167.5 0.1 7.1e-49 166.3 0.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RUS71898.1 - 5.2e-17 62.4 0.2 2.3e-16 60.3 0.2 2.2 1 0 0 1 1 1 1 uDENN domain GRAM PF02893.20 RUS71898.1 - 7.7e-16 58.0 0.0 4.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 GRAM domain C1_1 PF00130.22 RUS71898.1 - 1.2e-14 53.9 11.8 3.2e-14 52.6 11.8 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RUS71898.1 - 2.6e-11 44.0 0.1 9.3e-11 42.2 0.1 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS71898.1 - 3.2e-06 27.5 0.1 9.1e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RUS71898.1 - 0.0014 18.8 0.3 0.0045 17.2 0.3 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain SPA PF08616.10 RUS71898.1 - 0.0026 17.7 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis OrfB_Zn_ribbon PF07282.11 RUS71898.1 - 0.081 12.9 2.7 0.29 11.1 2.7 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_2 PF03107.16 RUS71898.1 - 0.96 9.8 9.9 3.2 8.1 9.9 1.9 1 0 0 1 1 1 0 C1 domain CNDH2_C PF16858.5 RUS71899.1 - 6.6e-70 236.3 2.7 6.6e-70 236.3 2.7 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 RUS71899.1 - 2.2e-37 127.7 0.3 2.2e-37 127.7 0.3 1.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_M PF16869.5 RUS71899.1 - 0.0075 17.0 1.9 0.0075 17.0 1.9 3.2 3 1 0 3 3 3 1 PF16858 DndB PF14072.6 RUS71899.1 - 0.055 12.7 0.1 0.094 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA-sulfur modification-associated zf-HIT PF04438.16 RUS71900.1 - 4.1e-07 29.7 14.3 6.8e-07 29.0 14.3 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 RUS71900.1 - 0.18 9.6 4.5 0.2 9.5 4.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 RUS71900.1 - 3.7 7.7 16.0 7.2 6.8 16.0 1.5 1 0 0 1 1 1 0 MYND finger Isochorismatase PF00857.20 RUS71901.1 - 6.3e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family IPPT PF01715.17 RUS71905.1 - 7.2e-08 32.5 0.3 1.5e-07 31.4 0.3 1.5 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 RUS71905.1 - 9.5e-05 22.6 0.7 0.00017 21.7 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF2072 PF09845.9 RUS71905.1 - 0.0014 18.9 1.7 0.0025 18.1 1.7 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein AKAP95 PF04988.12 RUS71905.1 - 0.0049 17.1 0.5 0.0087 16.3 0.5 1.5 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) DUF3449 PF11931.8 RUS71905.1 - 0.012 15.4 2.6 0.025 14.4 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) OrsD PF12013.8 RUS71905.1 - 0.034 14.6 1.9 0.06 13.8 1.4 1.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D ThiD2 PF17792.1 RUS71905.1 - 0.21 12.0 1.4 0.23 11.9 0.4 1.5 2 0 0 2 2 2 0 ThiD2 family Alpha_GJ PF03229.13 RUS71906.1 - 6.5 7.3 6.9 0.91 10.1 2.0 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J CLPTM1 PF05602.12 RUS71909.1 - 5.7e-147 490.2 2.0 7.4e-147 489.8 2.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 RUS71909.1 - 0.0016 18.1 4.7 0.58 10.0 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF4509 PF14970.6 RUS71910.1 - 2.6e-33 115.5 0.4 2.6e-33 115.5 0.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4509) DUF5082 PF16888.5 RUS71910.1 - 0.017 15.4 8.9 0.079 13.2 5.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) MSP1_C PF07462.11 RUS71910.1 - 0.021 13.5 0.4 0.021 13.5 0.4 2.5 3 0 0 3 3 3 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2046 PF09755.9 RUS71910.1 - 0.024 13.9 0.4 0.024 13.9 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) ApoO PF09769.9 RUS71910.1 - 0.043 13.8 1.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O LPP PF04728.13 RUS71910.1 - 0.49 10.8 3.8 0.82 10.1 0.7 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 RUS71910.1 - 0.63 10.1 8.3 3.7 7.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 RUS71911.1 - 8.8e-24 84.0 5.9 3.1e-23 82.3 5.9 2.0 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus Clathrin_H_link PF13838.6 RUS71911.1 - 2.5e-13 49.7 0.0 1.8e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Clathrin-H-link GAS PF13851.6 RUS71911.1 - 0.00011 21.6 8.4 0.00011 21.6 8.4 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding RPN6_C_helix PF18503.1 RUS71911.1 - 0.23 11.3 1.1 15 5.5 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain bZIP_2 PF07716.15 RUS71911.1 - 0.28 11.3 7.5 0.12 12.5 2.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 RUS71911.1 - 0.37 10.9 7.9 0.1 12.7 2.9 2.7 2 1 1 3 3 3 0 bZIP transcription factor HALZ PF02183.18 RUS71911.1 - 0.51 10.6 4.9 0.52 10.6 1.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper THOC7 PF05615.13 RUS71911.1 - 1.5 9.1 16.7 0.12 12.7 8.9 2.9 1 1 0 2 2 2 0 Tho complex subunit 7 Rx_N PF18052.1 RUS71911.1 - 1.5 9.2 7.0 0.16 12.3 1.1 2.5 2 1 1 3 3 3 0 Rx N-terminal domain DUF4047 PF13256.6 RUS71911.1 - 3.9 7.7 6.7 2 8.6 0.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) FAM104 PF15434.6 RUS71911.1 - 5.3 7.7 12.3 6.1 7.4 9.8 2.2 2 0 0 2 2 2 0 Family 104 AAA PF00004.29 RUS71912.1 - 2.9e-43 147.5 0.0 6.9e-43 146.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RUS71912.1 - 7e-10 38.7 0.1 3.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RUS71912.1 - 7.5e-10 38.5 0.1 1.8e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RUS71912.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RUS71912.1 - 1.2e-07 31.8 0.1 3.8e-07 30.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS71912.1 - 2e-05 25.0 0.1 0.0062 16.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 RUS71912.1 - 5.3e-05 22.5 0.1 0.00036 19.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RUS71912.1 - 0.00015 22.1 0.5 0.045 14.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 RUS71912.1 - 0.00016 21.4 0.0 0.00055 19.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RUS71912.1 - 0.00073 19.0 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS71912.1 - 0.0009 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 RUS71912.1 - 0.001 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RUS71912.1 - 0.0011 19.0 0.1 0.0062 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS71912.1 - 0.0012 18.6 0.1 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 RUS71912.1 - 0.0012 18.8 0.1 0.14 12.1 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 RUS71912.1 - 0.0012 19.0 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS71912.1 - 0.0019 18.7 0.1 0.011 16.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 RUS71912.1 - 0.0025 17.1 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 RUS71912.1 - 0.012 15.3 0.2 0.81 9.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 RUS71912.1 - 0.014 15.3 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 RUS71912.1 - 0.029 13.8 0.0 2.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein TsaE PF02367.17 RUS71912.1 - 0.034 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RUS71912.1 - 0.04 13.4 0.1 0.26 10.8 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 RUS71912.1 - 0.063 13.1 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RUS71912.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RUS71912.1 - 0.091 13.3 0.0 0.32 11.5 0.0 2.0 3 0 0 3 3 1 0 ABC transporter AAA_25 PF13481.6 RUS71912.1 - 0.13 11.8 2.5 0.2 11.2 0.2 2.2 2 1 1 3 3 3 0 AAA domain VWA PF00092.28 RUS71913.1 - 3e-15 56.9 0.2 4.3e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS71913.1 - 4e-07 30.6 0.2 1.1e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RUS71914.1 - 1e-141 468.7 25.1 9.4e-36 123.7 3.6 4.0 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.6 RUS71914.1 - 1.4e-54 183.2 5.3 7.6e-13 49.0 0.0 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_3 PF13768.6 RUS71914.1 - 1.5e-21 76.9 1.9 4.4e-07 30.0 0.0 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS71914.1 - 5.3e-07 29.2 5.6 0.0069 15.8 0.3 4.0 4 0 0 4 4 4 2 VWA domain containing CoxE-like protein Copine PF07002.16 RUS71914.1 - 0.00045 19.8 3.2 2.1 7.8 0.0 4.0 4 0 0 4 4 4 2 Copine TmoB PF06234.12 RUS71914.1 - 0.0072 16.4 2.4 2.8 8.1 0.0 3.7 4 0 0 4 4 4 2 Toluene-4-monooxygenase system protein B (TmoB) AhpC-TSA_2 PF13911.6 RUS71914.1 - 0.069 13.3 0.8 69 3.6 0.0 4.1 5 0 0 5 5 5 0 AhpC/TSA antioxidant enzyme F-box-like PF12937.7 RUS71915.1 - 1.6e-12 47.1 1.0 6.7e-12 45.1 1.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS71915.1 - 1.5e-06 27.9 0.2 6.9e-06 25.8 0.2 2.2 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 RUS71916.1 - 3.7e-09 36.0 5.3 0.033 14.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS71916.1 - 4.4e-06 26.4 3.1 0.048 13.8 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS71916.1 - 2.9e-05 24.5 0.0 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS71916.1 - 3.9e-05 24.2 0.0 0.016 15.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS71916.1 - 0.00015 21.9 0.3 0.012 15.9 0.0 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS71916.1 - 0.00075 20.1 0.0 3.7 8.6 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS71916.1 - 0.0015 18.1 1.1 0.85 9.3 0.0 3.4 2 1 1 3 3 3 2 TPR repeat ANAPC3 PF12895.7 RUS71916.1 - 0.0097 16.1 0.4 0.067 13.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RUS71916.1 - 0.011 16.0 0.2 0.74 10.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RUS71916.1 - 0.068 13.3 0.0 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS71916.1 - 0.13 13.0 0.1 1.3 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS71916.1 - 0.75 10.2 3.8 20 5.7 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat ApeC PF16977.5 RUS71917.1 - 4.8e-39 134.4 0.3 4.8e-39 134.4 0.3 1.9 2 0 0 2 2 2 1 C-terminal domain of apextrin Lectin_C PF00059.21 RUS71917.1 - 1.8e-34 118.7 3.6 3.9e-19 69.4 1.0 2.8 2 0 0 2 2 2 2 Lectin C-type domain Astacin PF01400.24 RUS71917.1 - 5.7e-24 84.8 0.1 1.1e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kringle PF00051.18 RUS71917.1 - 1.2e-11 44.7 3.7 1.2e-11 44.7 3.7 2.4 2 0 0 2 2 2 1 Kringle domain CUB PF00431.20 RUS71917.1 - 6.6e-08 32.9 0.0 1.9e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 RUS71917.1 - 4e-07 30.5 7.0 0.003 18.1 1.4 3.6 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Reprolysin_3 PF13582.6 RUS71917.1 - 0.029 14.9 0.5 0.078 13.5 0.5 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Chordopox_A33R PF05966.12 RUS71917.1 - 0.031 13.5 0.9 4 6.7 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus A33R protein LRR_8 PF13855.6 RUS71918.1 - 3.1e-06 26.9 1.3 1.3e-05 24.9 0.1 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 RUS71918.1 - 0.011 16.2 3.7 0.044 14.2 0.7 3.0 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) KIAA1328 PF15369.6 RUS71918.1 - 0.17 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 LRR_6 PF13516.6 RUS71918.1 - 0.3 11.2 0.9 37 4.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat PAXNEB PF05625.11 RUS71919.1 - 5.6e-104 348.2 0.0 6.4e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 RUS71919.1 - 0.02 14.2 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC Y_phosphatase PF00102.27 RUS71920.1 - 3.4e-71 239.6 0.0 4.4e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS71920.1 - 0.0036 17.1 0.6 0.01 15.7 0.6 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Orthoreo_P10 PF07204.11 RUS71920.1 - 0.013 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Y_phosphatase3 PF13350.6 RUS71920.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF2457 PF10446.9 RUS71921.1 - 0.086 12.0 3.5 0.1 11.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) mTERF PF02536.14 RUS71922.1 - 8.2e-15 54.5 0.8 1.2e-14 53.9 0.8 1.2 1 0 0 1 1 1 1 mTERF IQ PF00612.27 RUS71923.1 - 0.0009 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Tetraspanin PF00335.20 RUS71924.1 - 1.2e-10 41.5 1.8 4.4e-10 39.7 1.7 1.8 2 0 0 2 2 2 1 Tetraspanin family DUF4834 PF16118.5 RUS71924.1 - 0.0078 17.1 0.6 0.0078 17.1 0.6 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 RUS71924.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 TMEM9 Benyvirus_P25 PF05744.11 RUS71924.1 - 0.071 12.4 0.2 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 Benyvirus P25/P26 protein DUF4820 PF16091.5 RUS71925.1 - 0.004 16.5 0.1 0.004 16.5 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4820) Glyco_hydro_18 PF00704.28 RUS71926.1 - 1.7e-23 83.8 0.1 2.8e-23 83.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ADP_PFK_GK PF04587.15 RUS71928.1 - 1e-112 376.8 0.0 1.3e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region PfkB PF00294.24 RUS71928.1 - 0.04 13.2 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Imm2 PF14426.6 RUS71929.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm2 DUF1720 PF08226.11 RUS71930.1 - 2.7e-16 59.7 68.4 1.8e+04 -9.7 68.4 4.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Herpes_BLLF1 PF05109.13 RUS71930.1 - 0.00097 17.3 16.5 0.037 12.0 10.1 2.0 1 1 1 2 2 2 2 Herpes virus major outer envelope glycoprotein (BLLF1) RseA_C PF03873.13 RUS71930.1 - 0.024 14.9 22.9 1.8e+04 -13.3 22.9 7.1 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Med3 PF11593.8 RUS71931.1 - 0.0003 20.1 3.0 0.00038 19.8 3.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Syntaxin-6_N PF09177.11 RUS71931.1 - 0.047 14.2 2.3 0.12 12.9 1.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 RUS71931.1 - 0.23 11.9 1.3 18 5.8 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 RUS71931.1 - 0.25 11.5 3.7 14 5.9 0.1 2.7 3 0 0 3 3 3 0 Hr1 repeat DivIVA PF05103.13 RUS71931.1 - 0.37 10.9 2.7 0.51 10.4 1.2 1.8 1 1 1 2 2 2 0 DivIVA protein MGC-24 PF05283.11 RUS71931.1 - 0.42 11.1 5.1 0.76 10.2 5.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Calici_coat PF00915.20 RUS71931.1 - 0.45 9.4 3.7 0.67 8.8 3.7 1.2 1 0 0 1 1 1 0 Calicivirus coat protein Uso1_p115_C PF04871.13 RUS71931.1 - 1.7 9.1 3.7 1.2 9.5 0.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-RING_2 PF13639.6 RUS71932.1 - 2.5e-14 53.3 6.6 2.5e-14 53.3 6.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RUS71932.1 - 2.7e-11 43.0 3.3 9e-11 41.3 3.3 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS71932.1 - 5e-09 35.9 7.3 5e-09 35.9 7.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 RUS71932.1 - 4.7e-08 33.2 5.0 4.7e-08 33.2 5.0 2.8 4 0 0 4 4 2 1 zinc-ribbon zf-C3HC4_3 PF13920.6 RUS71932.1 - 2.9e-07 30.2 11.3 2.2e-06 27.4 3.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS71932.1 - 5.4e-07 29.5 2.9 5.4e-07 29.5 2.9 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS71932.1 - 1.2e-06 28.3 6.0 1.2e-06 28.3 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS71932.1 - 1.7e-06 28.2 7.7 1.7e-06 28.2 7.7 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RUS71932.1 - 2.5e-05 24.0 3.2 2.5e-05 24.0 3.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS71932.1 - 8.5e-05 22.4 4.8 8.5e-05 22.4 4.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RUS71932.1 - 0.00018 21.5 3.9 0.00082 19.4 3.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 RUS71932.1 - 0.021 14.6 2.2 0.044 13.6 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 RUS71932.1 - 0.036 14.1 0.9 0.036 14.1 0.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 RUS71932.1 - 0.038 14.0 9.2 0.16 12.0 0.8 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 RUS71932.1 - 0.057 13.4 10.8 0.11 12.5 1.0 2.8 2 1 1 3 3 3 0 zinc-ribbons C1_2 PF03107.16 RUS71932.1 - 0.19 12.0 13.8 0.28 11.5 1.3 3.5 3 1 0 3 3 3 0 C1 domain zf-H2C2_2 PF13465.6 RUS71932.1 - 0.29 11.7 4.7 1e+02 3.6 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_16 PF17034.5 RUS71932.1 - 0.29 11.4 3.6 0.29 11.4 1.9 1.7 1 1 0 1 1 1 0 Zinc-ribbon like family zf-RING_6 PF14835.6 RUS71932.1 - 0.52 10.2 4.0 0.16 11.9 0.8 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Laminin_EGF PF00053.24 RUS71932.1 - 1.4 9.1 9.7 4.2 7.6 0.6 3.1 3 0 0 3 3 3 0 Laminin EGF domain Zn_ribbon_17 PF17120.5 RUS71932.1 - 1.4 8.6 13.4 0.037 13.7 5.2 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf_UBZ PF18439.1 RUS71932.1 - 1.5 8.5 9.8 0.61 9.7 0.1 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger FANCL_C PF11793.8 RUS71932.1 - 1.8 8.8 13.8 0.45 10.7 6.3 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 RUS71932.1 - 3.3 8.0 8.3 0.15 12.4 1.3 2.2 2 1 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_10 PF16685.5 RUS71932.1 - 6 7.1 8.9 1.7 8.8 2.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc_ribbon_2 PF13240.6 RUS71932.1 - 7.9 6.3 7.8 8.7 6.2 3.9 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 RUS71932.1 - 8.3 6.3 13.5 0.039 13.8 4.2 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DpnI PF06044.12 RUS71932.1 - 8.6 6.0 6.1 37 3.9 0.1 3.0 2 1 0 3 3 3 0 Dam-replacing family LIM PF00412.22 RUS71932.1 - 8.8 6.6 11.7 12 6.2 3.1 3.7 2 2 2 4 4 4 0 LIM domain ABC_membrane PF00664.23 RUS71933.1 - 1.5e-90 303.6 14.2 7.5e-61 206.2 8.5 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS71933.1 - 6.6e-74 246.9 0.1 9.6e-37 126.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS71933.1 - 8.7e-11 41.7 2.4 3e-05 23.6 0.1 3.9 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS71933.1 - 2e-09 37.8 0.3 0.00086 19.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS71933.1 - 9.8e-09 35.8 0.2 0.0023 18.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RUS71933.1 - 5.7e-08 32.0 0.5 0.00059 18.8 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 RUS71933.1 - 4.4e-07 30.0 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 RUS71933.1 - 2.6e-06 27.5 0.0 0.13 12.2 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA PF00004.29 RUS71933.1 - 5.3e-06 26.9 0.8 0.35 11.3 0.0 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS71933.1 - 6.3e-06 26.2 0.0 0.26 11.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) G-alpha PF00503.20 RUS71933.1 - 8.2e-06 25.2 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 RUS71933.1 - 8.3e-06 25.4 0.0 0.053 13.0 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 RUS71933.1 - 1.2e-05 24.7 0.0 0.0098 15.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 RUS71933.1 - 1.6e-05 24.6 0.1 0.17 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF815 PF05673.13 RUS71933.1 - 0.00023 20.4 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 RUS71933.1 - 0.00023 21.0 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RUS71933.1 - 0.00055 19.7 0.1 1.5 8.5 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RUS71933.1 - 0.0012 18.4 0.1 0.2 11.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RUS71933.1 - 0.0018 18.6 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 RUS71933.1 - 0.0021 18.3 8.4 0.41 10.9 0.1 4.4 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 RUS71933.1 - 0.0031 17.7 0.0 2.8 8.0 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain NACHT PF05729.12 RUS71933.1 - 0.0033 17.3 0.4 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 RUS71933.1 - 0.0035 17.4 0.1 4.8 7.2 0.0 3.4 3 1 0 3 3 2 1 AAA domain PRK PF00485.18 RUS71933.1 - 0.0041 16.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 RUS71933.1 - 0.0059 16.3 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 RUS71933.1 - 0.012 15.4 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RUS71933.1 - 0.022 14.0 0.1 6.7 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 RUS71933.1 - 0.04 14.5 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RUS71933.1 - 0.064 13.5 0.3 12 6.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 RUS71933.1 - 0.069 13.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 RUS71933.1 - 0.071 13.3 0.0 11 6.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 RUS71933.1 - 0.076 12.4 0.0 31 3.9 0.0 3.5 5 0 0 5 5 4 0 Bacterial TniB protein tRNA_lig_kinase PF08303.11 RUS71933.1 - 0.079 13.0 0.0 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2594 PF10769.9 RUS71933.1 - 0.082 13.0 0.4 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) MMR_HSR1 PF01926.23 RUS71933.1 - 0.16 12.0 0.0 8.1 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 RUS71933.1 - 0.17 11.6 0.5 4.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 RUS71933.1 - 0.18 12.3 0.0 16 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain 7tm_2 PF00002.24 RUS71936.1 - 1.1e-46 159.1 18.4 1.1e-41 142.8 14.0 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS71936.1 - 0.013 15.8 0.6 0.013 15.8 0.6 1.7 2 0 0 2 2 2 0 Hormone receptor domain 7tm_1 PF00001.21 RUS71936.1 - 4.6 6.5 11.9 26 4.0 11.4 2.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RIC1 PF07064.13 RUS71937.1 - 1.5e-85 286.7 0.2 1.5e-85 286.7 0.2 1.8 2 0 0 2 2 2 1 RIC1 ANAPC4_WD40 PF12894.7 RUS71937.1 - 4.3e-05 23.7 0.1 0.055 13.8 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tctex-1 PF03645.13 RUS71938.1 - 8.8e-27 93.4 0.0 1.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.32 RUS71940.1 - 0.00012 22.7 2.5 0.47 11.4 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF908 PF06012.12 RUS71940.1 - 6.5 6.1 5.6 11 5.3 5.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FAM76 PF16046.5 RUS71941.1 - 0.016 14.6 7.5 0.022 14.1 7.5 1.3 1 0 0 1 1 1 0 FAM76 protein HD_2 PF12917.7 RUS71941.1 - 0.038 13.8 1.9 0.042 13.6 0.8 1.5 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme TRAF_BIRC3_bd PF16673.5 RUS71941.1 - 0.049 13.4 5.2 0.11 12.3 1.2 2.9 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 RUS71941.1 - 0.083 13.1 16.3 0.48 10.6 3.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2009 PF09418.10 RUS71941.1 - 0.089 11.9 1.6 0.12 11.5 1.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) PTPS_related PF10131.9 RUS71941.1 - 0.14 10.5 0.1 0.15 10.3 0.1 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF4407 PF14362.6 RUS71941.1 - 0.17 11.2 3.2 0.25 10.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAP1_N PF04849.13 RUS71941.1 - 0.31 10.2 13.8 0.4 9.8 13.8 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SlyX PF04102.12 RUS71941.1 - 0.4 11.3 14.3 1.6 9.4 4.7 2.7 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.19 RUS71941.1 - 0.6 8.0 5.4 0.67 7.8 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 RUS71941.1 - 0.67 9.5 6.7 0.81 9.2 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 RUS71941.1 - 0.68 8.8 14.8 0.96 8.3 14.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YscO-like PF16789.5 RUS71941.1 - 0.82 9.7 10.9 3.6 7.6 8.0 2.2 1 1 1 2 2 2 0 YscO-like protein NPV_P10 PF05531.12 RUS71941.1 - 1.3 9.6 5.1 2.9 8.4 1.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 RUS71941.1 - 1.3 9.5 11.1 2.7 8.5 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 RUS71941.1 - 1.7 8.8 11.0 1.3 9.2 8.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 RUS71941.1 - 2.7 6.8 4.7 3.1 6.6 4.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 RUS71941.1 - 5.1 6.9 11.7 4.1 7.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.7 RUS71941.1 - 7.1 6.8 18.1 4.7 7.4 7.6 2.3 1 1 1 2 2 2 0 Tropomyosin like SAS-6_N PF16531.5 RUS71942.1 - 4.4e-25 88.1 1.0 4.4e-25 88.1 1.0 2.4 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 RUS71942.1 - 3.8e-07 29.8 0.4 3.8e-07 29.8 0.4 3.6 3 0 0 3 3 3 1 Sas6/XLF/XRCC4 coiled-coil domain DUF3398 PF11878.8 RUS71942.1 - 0.017 15.5 0.0 0.1 13.1 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Spc7 PF08317.11 RUS71942.1 - 0.22 10.3 69.1 0.014 14.3 18.4 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein WD40 PF00400.32 RUS71943.1 - 2.3e-41 139.0 22.7 1.2e-08 35.4 0.2 7.6 6 1 1 7 7 7 7 WD domain, G-beta repeat U-box PF04564.15 RUS71943.1 - 2.3e-23 82.2 0.2 3.8e-23 81.4 0.2 1.4 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.30 RUS71943.1 - 5.4e-19 68.4 0.0 1.3e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS71943.1 - 2.9e-15 56.1 0.0 6.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nup160 PF11715.8 RUS71943.1 - 2.4e-08 33.1 1.0 0.036 12.7 0.2 3.1 3 0 0 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RUS71943.1 - 1.2e-07 31.9 0.0 1.4 9.3 0.0 5.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS71943.1 - 1.6e-06 27.3 0.8 0.013 14.5 0.0 3.7 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SAM_Ste50p PF09235.10 RUS71943.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Ste50p, sterile alpha motif eIF2A PF08662.11 RUS71943.1 - 0.0027 17.6 2.2 4.3 7.2 0.0 4.1 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A zf-NOSIP PF15906.5 RUS71943.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein SAM_PNT PF02198.16 RUS71943.1 - 0.01 15.8 0.1 0.044 13.8 0.1 2.0 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Peptidase_C21 PF05381.12 RUS71943.1 - 0.012 15.9 0.1 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase zf-Nse PF11789.8 RUS71943.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PALB2_WD40 PF16756.5 RUS71943.1 - 0.022 13.7 0.1 0.043 12.7 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 RUS71943.1 - 0.037 14.0 0.1 28 4.8 0.1 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 RUS71943.1 - 0.071 12.4 1.3 0.33 10.2 0.1 2.6 4 0 0 4 4 4 0 WD40-like domain SAM_3 PF18016.1 RUS71943.1 - 0.12 12.2 0.3 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PEHE PF15275.6 RUS71945.1 - 1.1e-08 35.8 2.2 1.1e-08 35.8 2.2 3.8 3 0 0 3 3 3 1 PEHE domain Prim_Zn_Ribbon PF08273.12 RUS71945.1 - 0.075 13.3 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase SWIRM-assoc_2 PF16496.5 RUS71946.1 - 9.3e-121 403.6 50.2 1.9e-90 303.7 0.2 4.4 2 1 1 3 3 3 2 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 RUS71946.1 - 8.5e-31 106.2 0.0 1.9e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 RUS71946.1 - 7e-29 99.6 14.0 1.7e-28 98.4 14.0 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 RUS71946.1 - 3e-27 94.7 3.9 3e-27 94.7 3.9 2.5 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 RUS71946.1 - 9.5e-11 41.7 0.2 9.5e-11 41.7 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS71946.1 - 1.9e-05 24.8 0.0 4.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRCT_2 PF16589.5 RUS71946.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ank_2 PF12796.7 RUS71947.1 - 4.2e-39 133.0 6.8 1.6e-12 47.8 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS71947.1 - 5.6e-28 93.9 1.7 0.0017 18.7 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 RUS71947.1 - 3.4e-27 94.1 0.6 2e-08 34.3 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS71947.1 - 6.6e-27 93.5 1.4 3.8e-07 30.5 0.0 6.2 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS71947.1 - 2e-21 75.4 9.1 0.0057 17.1 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat SOCS_box PF07525.16 RUS71947.1 - 9.3e-10 38.7 0.6 2.4e-09 37.4 0.6 1.7 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.25 RUS71948.1 - 7.1e-77 258.3 0.0 8.1e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS71948.1 - 2.2e-35 122.2 0.0 3.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS71948.1 - 2.5e-06 26.7 0.2 4e-05 22.7 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS71948.1 - 0.0012 18.8 0.1 0.031 14.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS71948.1 - 0.0039 16.6 0.0 0.015 14.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 RUS71948.1 - 0.0097 15.3 0.1 0.022 14.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS71948.1 - 0.034 13.8 0.1 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RUS71948.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Trypsin PF00089.26 RUS71950.1 - 5.1e-47 160.5 0.0 5.1e-47 160.5 0.0 2.1 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 RUS71950.1 - 6.6e-06 27.1 0.0 2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S6 PF02395.16 RUS71950.1 - 0.022 12.9 0.0 0.035 12.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease Gluconate_2-dh3 PF13618.6 RUS71950.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 KAR9 PF08580.10 RUS71950.1 - 6.2 5.2 12.0 9.1 4.7 12.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FAST_2 PF08368.12 RUS71951.1 - 0.019 15.8 0.0 0.061 14.1 0.0 1.9 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Atypical_Card PF18461.1 RUS71951.1 - 0.094 12.9 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 Atypical caspase recruitment domain FAST_1 PF06743.15 RUS71951.1 - 0.11 12.5 2.1 0.44 10.5 0.1 3.0 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 1 FGGY_N PF00370.21 RUS71952.1 - 9.3e-23 81.1 0.0 4.4e-20 72.3 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RUS71952.1 - 4.3e-19 69.0 0.0 8.3e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BTB PF00651.31 RUS71953.1 - 3.2e-18 66.0 0.1 6.9e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS71953.1 - 1e-06 28.7 0.5 0.00011 22.2 0.1 2.9 3 0 0 3 3 3 1 BTB And C-terminal Kelch DUF3342 PF11822.8 RUS71953.1 - 0.076 13.2 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) PP2C_2 PF13672.6 RUS71954.1 - 2.2e-12 47.1 0.0 3.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RUS71954.1 - 0.0001 22.3 0.0 0.00049 20.1 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Chromo_shadow PF01393.19 RUS71955.1 - 2e-32 111.1 0.1 3.1e-29 100.8 0.0 2.4 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 RUS71955.1 - 3.3e-22 78.1 0.3 2.9e-19 68.7 0.1 2.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain TIR PF01582.20 RUS71956.1 - 3.1e-25 89.0 0.0 5.6e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS71956.1 - 1.1e-19 71.2 0.1 1.7e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 RUS71956.1 - 2.4e-05 24.7 0.0 6e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) TMCCDC2 PF15844.5 RUS71956.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Toxin_3 PF00537.18 RUS71956.1 - 0.34 11.1 10.2 0.68 10.2 10.2 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain EGF_2 PF07974.13 RUS71957.1 - 0.0097 16.3 5.9 0.0097 16.3 5.9 2.4 2 0 0 2 2 2 1 EGF-like domain SOG2 PF10428.9 RUS71957.1 - 0.71 9.0 3.4 0.82 8.8 3.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein GRIM-19 PF06212.12 RUS71958.1 - 3.8e-41 140.1 0.1 4.4e-41 139.9 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein CBP4 PF07960.11 RUS71958.1 - 0.094 12.6 0.2 0.91 9.4 0.1 2.1 2 0 0 2 2 2 0 CBP4 TACC_C PF05010.14 RUS71959.1 - 3.3e-49 167.4 30.1 3.3e-49 167.4 30.1 1.6 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT57 PF10498.9 RUS71959.1 - 0.0018 17.3 15.0 0.0018 17.3 15.0 2.3 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 ATP-synt_DE PF00401.20 RUS71959.1 - 0.011 15.9 2.6 0.011 15.9 2.6 3.2 3 0 0 3 3 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain EzrA PF06160.12 RUS71959.1 - 0.019 13.2 21.5 0.028 12.6 21.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 RUS71959.1 - 0.019 12.5 27.9 0.029 11.9 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 RUS71959.1 - 0.071 12.5 22.8 2.1 7.7 2.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 RUS71959.1 - 0.14 11.5 21.0 0.3 10.4 19.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4047 PF13256.6 RUS71959.1 - 0.25 11.5 7.3 0.61 10.3 7.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF1664 PF07889.12 RUS71959.1 - 0.59 10.2 16.9 0.41 10.7 7.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Aminopep PF10023.9 RUS71959.1 - 1.1 8.6 10.9 0.78 9.0 9.4 1.5 1 1 0 1 1 1 0 Putative aminopeptidase BLOC1_2 PF10046.9 RUS71959.1 - 1.7 9.0 17.4 1.5 9.2 5.1 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 RUS71959.1 - 2 7.2 37.2 3.8 6.3 16.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 RUS71959.1 - 2.3 7.6 28.3 6.2 6.2 28.3 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 5 Prefoldin_2 PF01920.20 RUS71959.1 - 4.3 7.3 33.6 1.1 9.2 3.4 4.3 2 1 2 5 5 4 0 Prefoldin subunit V-ATPase_G_2 PF16999.5 RUS71959.1 - 4.6 7.7 25.7 0.58 10.6 7.1 3.1 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF5082 PF16888.5 RUS71959.1 - 4.6 7.6 20.5 8.7 6.6 3.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF148 PF02520.17 RUS71959.1 - 6.5 6.9 18.2 6.1 7.0 5.2 2.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF724 PF05266.14 RUS71959.1 - 7.5 6.3 32.2 2.4 7.9 10.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.19 RUS71959.1 - 7.6 6.2 30.7 1.4 8.6 9.4 3.2 1 1 2 3 3 3 0 GrpE Baculo_PEP_C PF04513.12 RUS71959.1 - 7.9 6.5 11.7 17 5.4 2.2 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 RUS71959.1 - 8.7 6.7 24.8 7.7 6.9 4.3 4.4 1 1 4 5 5 5 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 RUS71959.1 - 8.9 7.0 39.2 0.36 11.5 8.0 4.1 2 1 2 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HrpB7 PF09486.10 RUS71959.1 - 9.2 6.6 25.0 20 5.5 11.3 3.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) RNase_H PF00075.24 RUS71960.1 - 3.2e-09 37.1 0.0 1.2e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS71960.1 - 0.0032 18.1 1.8 0.004 17.8 0.7 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 RUS71960.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like LRR_8 PF13855.6 RUS71961.1 - 4.4e-28 96.8 62.3 3.9e-07 29.7 2.3 4.5 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RUS71961.1 - 7e-16 58.1 29.0 5.4e-05 23.5 0.5 5.3 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS71961.1 - 4.4e-06 26.3 11.5 0.28 10.7 1.8 3.2 1 1 1 3 3 3 3 Leucine-rich repeat RsmF_methylt_CI PF17126.5 RUS71961.1 - 0.0049 16.9 0.1 5.8 7.0 0.0 3.7 3 2 2 5 5 5 2 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 RUS71961.1 - 0.65 10.8 32.7 13 6.8 1.7 7.8 9 0 0 9 9 9 0 Leucine Rich Repeat Creatinase_N_2 PF16189.5 RUS71962.1 - 9.1e-50 168.9 0.2 1.9e-49 167.9 0.2 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 RUS71962.1 - 4.9e-42 144.0 0.0 7.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 RUS71962.1 - 4.9e-23 81.0 2.0 8.4e-23 80.2 0.6 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 RUS71962.1 - 6.7e-16 59.1 0.0 1.7e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Put_Phosphatase PF06888.12 RUS71963.1 - 2.7e-71 239.7 0.1 2.9e-71 239.6 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 RUS71963.1 - 1.2e-05 25.8 0.1 0.00017 22.0 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fibrillarin_2 PF10113.9 RUS71963.1 - 0.077 11.6 0.0 0.16 10.6 0.0 1.4 2 0 0 2 2 2 0 Fibrillarin-like archaeal protein DUF2608 PF11019.8 RUS71963.1 - 0.079 12.4 0.3 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) DnaB PF00772.21 RUS71963.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain Med2 PF11214.8 RUS71963.1 - 0.15 12.3 0.2 0.36 11.0 0.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Acyltransferase PF01553.21 RUS71964.1 - 3.4e-22 78.5 0.1 6.6e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase HSP70 PF00012.20 RUS71965.1 - 4.3e-273 907.0 14.7 4.9e-273 906.8 14.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS71965.1 - 1.2e-16 60.4 1.5 9.7e-14 50.9 0.5 2.7 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 RUS71965.1 - 0.00015 22.1 3.0 0.48 10.9 0.1 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RUS71965.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain IMD PF08397.11 RUS71965.1 - 2.8 7.2 9.3 13 5.1 6.7 2.4 2 0 0 2 2 2 0 IRSp53/MIM homology domain Pentapeptide PF00805.22 RUS71966.1 - 2.1e-36 123.1 23.4 5.3e-14 51.5 3.2 4.8 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 RUS71966.1 - 2.9e-20 72.2 0.3 5.2e-11 42.6 0.0 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 RUS71966.1 - 1.4e-19 70.0 0.0 1.9e-07 31.1 0.0 3.7 3 1 1 4 4 4 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 RUS71966.1 - 2.8e-11 43.6 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 RUS71966.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DNA_ligase_OB PF03120.16 RUS71966.1 - 0.054 13.4 0.1 2.7 7.9 0.1 2.6 1 1 1 2 2 2 0 NAD-dependent DNA ligase OB-fold domain Tubulin PF00091.25 RUS71967.1 - 2e-68 230.5 0.0 2.5e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS71967.1 - 2.1e-20 73.2 0.2 3.6e-20 72.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS71967.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain UBX PF00789.20 RUS71968.1 - 2.1e-13 50.3 0.1 3.5e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 UBX domain ATP-synt_E PF05680.12 RUS71968.1 - 0.95 9.8 6.1 1.4 9.3 6.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain Calreticulin PF00262.18 RUS71970.1 - 1.6e-80 270.8 18.9 1.1e-59 202.2 6.8 3.0 2 1 1 3 3 3 2 Calreticulin family MDM10 PF12519.8 RUS71970.1 - 1.5 7.6 3.6 2.9 6.7 3.6 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SAPS PF04499.15 RUS71970.1 - 6.2 5.5 6.9 9.9 4.8 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4131 PF13567.6 RUS71971.1 - 1.8 8.2 6.0 4 7.1 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PID PF00640.23 RUS71972.1 - 9e-06 25.8 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) RCC1 PF00415.18 RUS71973.1 - 1.5e-59 198.4 11.2 7.9e-12 45.6 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS71973.1 - 7.2e-27 92.6 37.3 3.1e-07 30.0 0.4 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 RUS71973.1 - 0.016 15.6 0.1 9 6.8 0.0 3.1 3 0 0 3 3 3 0 SUKH-3 immunity protein SDA1 PF05285.12 RUS71974.1 - 3.8e-06 26.6 32.5 6.3e-06 25.8 32.5 1.3 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 RUS71974.1 - 0.00057 18.5 24.0 0.0011 17.5 24.0 1.4 1 0 0 1 1 1 1 Mpp10 protein FMN_bind PF04205.14 RUS71974.1 - 0.0086 16.6 6.6 1.1 9.9 0.0 3.9 3 0 0 3 3 3 1 FMN-binding domain AC_N PF16214.5 RUS71974.1 - 1 8.4 3.0 2.3 7.3 3.0 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Nop14 PF04147.12 RUS71974.1 - 1.8 6.7 47.1 3.2 5.9 46.7 1.5 1 1 0 1 1 1 0 Nop14-like family Suf PF05843.14 RUS71974.1 - 4.9 7.0 7.5 0.27 11.2 0.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DivIC PF04977.15 RUS71974.1 - 5 7.0 9.1 9.9 6.0 9.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Inositol_P PF00459.25 RUS71975.1 - 5.4e-41 140.9 0.3 6.9e-41 140.6 0.3 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Ig_3 PF13927.6 RUS71978.1 - 1.3e-23 83.3 6.4 1.1e-08 35.5 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS71978.1 - 9.9e-23 80.0 0.6 1.1e-08 35.0 0.0 4.6 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS71978.1 - 6.1e-13 48.9 6.1 0.007 16.7 0.0 4.7 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS71978.1 - 7.2e-13 48.5 3.4 0.00021 21.4 0.1 4.8 4 1 0 4 4 4 4 Immunoglobulin domain GPI-anchored PF10342.9 RUS71978.1 - 0.36 11.6 7.0 1.7 9.5 0.1 3.4 4 0 0 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family I-set PF07679.16 RUS71980.1 - 0.075 13.1 0.7 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain REJ PF02010.15 RUS71981.1 - 1.2e-44 152.8 16.9 3.8e-44 151.2 6.6 3.0 2 1 0 2 2 2 2 REJ domain PKD PF00801.20 RUS71981.1 - 7.4e-29 99.4 16.2 1e-09 38.1 0.1 6.1 6 0 0 6 6 6 4 PKD domain PKD_3 PF16820.5 RUS71981.1 - 2e-16 59.5 0.9 1.3e-05 24.9 0.0 5.4 6 0 0 6 6 6 3 PKD-like domain Y_Y_Y PF07495.13 RUS71981.1 - 0.00015 21.6 0.2 1.6 8.7 0.0 4.1 4 0 0 4 4 4 2 Y_Y_Y domain SusE PF14292.6 RUS71981.1 - 0.069 13.4 12.4 1.6 9.0 0.0 4.5 4 1 1 5 5 5 0 SusE outer membrane protein TcfC PF16967.5 RUS71981.1 - 0.075 12.5 0.3 0.52 9.8 0.0 2.5 3 0 0 3 3 3 0 E-set like domain BiPBP_C PF06832.12 RUS71981.1 - 0.1 12.7 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family WIF PF02019.18 RUS71981.1 - 0.15 11.7 0.7 6.3 6.5 0.0 3.5 3 1 1 4 4 4 0 WIF domain Lipocalin_4 PF13648.6 RUS71981.1 - 6.2 7.9 8.5 11 7.0 0.2 4.0 4 1 0 4 4 4 0 Lipocalin-like domain PLAT PF01477.23 RUS71982.1 - 5.1e-19 69.0 0.0 8.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain GPS PF01825.21 RUS71982.1 - 3.4e-07 30.7 9.5 8.3e-07 29.4 9.5 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Osw5 PF17062.5 RUS71982.1 - 3.3 7.9 6.7 0.44 10.7 0.6 2.3 2 0 0 2 2 2 0 Outer spore wall 5 PKD_channel PF08016.12 RUS71983.1 - 0.00029 19.6 1.5 0.00063 18.5 0.0 1.9 2 0 0 2 2 2 1 Polycystin cation channel PKD_channel PF08016.12 RUS71984.1 - 1.3e-26 93.2 15.1 1.9e-26 92.7 15.1 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RUS71984.1 - 4.7e-08 32.6 16.8 7.6e-08 31.9 16.8 1.3 1 0 0 1 1 1 1 Ion transport protein PS_pyruv_trans PF04230.13 RUS71985.1 - 1.3e-16 61.4 0.3 4e-07 30.2 0.0 2.6 3 0 0 3 3 3 2 Polysaccharide pyruvyl transferase TPT PF03151.16 RUS71985.1 - 0.04 13.2 1.8 0.063 12.6 1.8 1.3 1 0 0 1 1 1 0 Triose-phosphate Transporter family ATP-synt_I PF03899.15 RUS71985.1 - 0.21 12.0 1.5 0.45 10.9 0.5 1.9 1 1 0 1 1 1 0 ATP synthase I chain Prominin PF05478.11 RUS71991.1 - 0.00018 19.6 0.0 0.0002 19.5 0.0 1.0 1 0 0 1 1 1 1 Prominin MlaA PF04333.13 RUS71991.1 - 0.053 13.2 0.4 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 MlaA lipoprotein Baculo_PEP_C PF04513.12 RUS71991.1 - 6.6 6.8 8.2 16 5.5 0.8 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus An_peroxidase PF03098.15 RUS71992.1 - 7.8e-143 476.8 0.0 1.2e-142 476.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 RUS71992.1 - 2.7e-27 95.8 0.0 5.3e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RUS71992.1 - 8.2e-19 67.7 0.0 1.7e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RUS71992.1 - 3e-14 53.2 14.4 6.7e-14 52.1 14.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 RUS71992.1 - 4.7e-10 38.3 7.1 0.00012 21.4 0.4 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS71992.1 - 5.1e-09 36.5 3.3 0.00015 22.2 0.8 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS71992.1 - 3.2e-07 29.7 10.5 0.033 14.1 0.4 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RUS71992.1 - 0.00016 21.0 0.5 0.047 13.2 0.1 3.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RUS71992.1 - 0.00061 19.6 2.6 0.0015 18.4 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair NAD_binding_1 PF00175.21 RUS71992.1 - 0.0048 17.5 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Spaetzle PF16077.5 RUS71994.1 - 9.5e-05 22.9 0.1 0.0002 21.8 0.1 1.5 1 0 0 1 1 1 1 Spaetzle PSA_CBD PF18341.1 RUS71994.1 - 0.12 12.5 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain zf-CCCH_2 PF14608.6 RUS71995.1 - 0.25 11.9 1.7 0.36 11.4 0.4 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Sugar_tr PF00083.24 RUS71996.1 - 4.3e-87 292.8 30.4 5.4e-87 292.5 30.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS71996.1 - 1.2e-26 93.5 72.3 9.9e-23 80.6 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS71996.1 - 3.9e-07 29.7 1.9 3.9e-07 29.7 1.9 2.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 RUS71996.1 - 0.0003 19.2 14.5 0.018 13.3 8.2 3.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATP1G1_PLM_MAT8 PF02038.16 RUS71996.1 - 0.63 9.5 3.2 0.53 9.8 0.6 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1201 PF06716.11 RUS71996.1 - 4.7 7.3 10.6 0.32 11.0 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Tubulin PF00091.25 RUS71997.1 - 5.6e-70 235.6 0.0 9.8e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS71997.1 - 8.4e-48 161.7 0.2 1.6e-47 160.8 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS71997.1 - 0.00022 21.5 0.0 0.00057 20.2 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RUS71997.1 - 0.00036 19.8 0.1 0.00095 18.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Reticulon PF02453.17 RUS71998.1 - 0.0028 17.6 7.5 0.0048 16.9 7.5 1.3 1 0 0 1 1 1 1 Reticulon CPBP PF02517.16 RUS71998.1 - 2.9 8.3 9.6 1.7 9.1 1.0 2.3 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease EF-hand_7 PF13499.6 RUS71999.1 - 1.2e-19 70.5 3.4 1.4e-12 47.9 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS71999.1 - 2e-19 67.6 9.1 1.3e-07 30.7 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RUS71999.1 - 2.3e-15 55.1 5.4 9.8e-07 28.2 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS71999.1 - 3.3e-11 42.8 5.1 0.0051 16.6 0.1 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS71999.1 - 8.7e-11 40.8 8.7 1.3e-05 24.4 0.1 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 RUS71999.1 - 2e-06 28.1 1.5 0.00029 21.1 0.2 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS71999.1 - 0.0099 15.8 3.0 1.3 9.0 0.6 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EURL PF06937.11 RUS71999.1 - 0.039 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 EURL protein Retrotrans_gag PF03732.17 RUS71999.1 - 0.039 14.2 0.2 0.065 13.5 0.2 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein EF-hand_11 PF08976.11 RUS71999.1 - 0.092 13.6 0.1 0.39 11.6 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 RUS71999.1 - 1.2 9.1 4.8 0.58 10.1 0.5 2.5 2 1 1 3 3 3 0 EF hand VWD PF00094.25 RUS72000.1 - 6.3e-35 120.8 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 RUS72000.1 - 7.8e-16 58.1 45.8 2.5e-08 34.1 16.8 2.9 3 0 0 3 3 3 2 von Willebrand factor type C domain DUF2367 PF10164.9 RUS72003.1 - 0.079 13.5 5.9 0.12 12.9 5.9 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) zf-H2C2_2 PF13465.6 RUS72005.1 - 0.11 12.9 0.8 0.44 11.1 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Homeodomain PF00046.29 RUS72006.1 - 6.6e-21 73.9 3.0 1.2e-20 73.1 3.0 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS72006.1 - 0.022 14.6 3.9 0.04 13.8 3.9 1.4 1 0 0 1 1 1 0 OAR domain Homeobox_KN PF05920.11 RUS72006.1 - 0.025 14.5 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain GFD1 PF17331.2 RUS72008.1 - 0.0036 17.4 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 GFD1 mRNA transport factor Glyco_hydro_18 PF00704.28 RUS72009.1 - 1.9e-86 290.7 0.0 2.4e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 RUS72009.1 - 1.6e-23 82.6 14.2 1.1e-11 44.7 1.1 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain zf-MYND PF01753.18 RUS72011.1 - 3.8e-09 36.5 12.1 1e-08 35.1 12.1 1.8 1 0 0 1 1 1 1 MYND finger BUD22 PF09073.10 RUS72012.1 - 0.0016 17.9 49.0 0.0022 17.4 49.0 1.2 1 0 0 1 1 1 1 BUD22 MCRS_N PF13325.6 RUS72013.1 - 1.3e-87 293.0 0.5 1.8e-87 292.5 0.5 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.26 RUS72013.1 - 0.0003 21.1 0.1 0.00071 19.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.25 RUS72015.1 - 1.7e-68 230.9 0.0 1.1e-67 228.2 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain cNMP_binding PF00027.29 RUS72015.1 - 2.2e-43 146.2 0.0 2.8e-20 72.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 RUS72015.1 - 3.1e-35 121.7 0.0 6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PKcGMP_CC PF16808.5 RUS72015.1 - 1.4e-10 40.8 11.1 3.2e-10 39.7 11.1 1.7 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Kinase-like PF14531.6 RUS72015.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like P4Ha_N PF08336.11 RUS72015.1 - 0.00047 20.2 0.7 0.00096 19.2 0.7 1.6 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cupin_3 PF05899.12 RUS72015.1 - 0.045 13.4 0.5 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) FTA2 PF13095.6 RUS72015.1 - 0.063 12.9 0.2 14 5.2 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS72015.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 RUS72015.1 - 0.11 13.2 1.5 0.24 12.1 1.5 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF641 PF04859.12 RUS72015.1 - 8.3 6.8 7.2 1.2 9.5 2.3 2.1 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 RUS72017.1 - 0.0034 17.8 0.1 0.005 17.3 0.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein FlgN PF05130.12 RUS72017.1 - 0.0077 16.8 0.1 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 FlgN protein Med4 PF10018.9 RUS72017.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 PKcGMP_CC PF16808.5 RUS72017.1 - 0.011 15.6 4.5 0.011 15.6 4.5 2.8 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PV-1 PF06637.11 RUS72017.1 - 0.026 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF641 PF04859.12 RUS72017.1 - 0.046 14.1 0.1 0.064 13.6 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 RUS72017.1 - 0.098 11.5 0.5 0.14 11.1 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.8 RUS72017.1 - 0.2 11.0 2.1 0.29 10.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PH PF00169.29 RUS72018.1 - 1.7e-23 83.1 0.4 9.5e-12 45.4 0.1 3.0 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.20 RUS72018.1 - 2.8e-23 83.1 0.2 2.8e-23 83.1 0.2 2.1 3 0 0 3 3 3 1 RhoGEF domain FERM_C PF09380.10 RUS72018.1 - 2e-22 79.3 1.6 4.8e-22 78.2 1.6 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS72018.1 - 1.9e-18 66.9 0.3 2e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 FERM central domain FA PF08736.11 RUS72018.1 - 2.3e-13 50.0 2.0 1.5e-12 47.3 0.4 2.5 2 0 0 2 2 2 1 FERM adjacent (FA) PH_13 PF16652.5 RUS72018.1 - 1e-06 28.7 1.7 0.066 13.0 0.8 3.0 2 1 0 2 2 2 2 Pleckstrin homology domain FERM_N PF09379.10 RUS72018.1 - 4.1e-06 26.7 0.1 1.3e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain IQ_SEC7_PH PF16453.5 RUS72018.1 - 5.6e-06 26.4 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RUS72018.1 - 7.8e-05 23.0 2.4 0.047 14.0 1.0 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 RUS72018.1 - 0.0062 16.8 0.1 0.071 13.4 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DUF5639 PF18690.1 RUS72018.1 - 0.028 14.5 0.1 0.066 13.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) PH_11 PF15413.6 RUS72018.1 - 0.12 12.8 6.7 2.3 8.7 1.1 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain SR-25 PF10500.9 RUS72020.1 - 0.00044 19.9 11.4 0.00044 19.9 11.4 4.2 4 1 0 4 4 4 3 Nuclear RNA-splicing-associated protein MAS20 PF02064.15 RUS72020.1 - 1.5 8.9 7.8 4.2 7.5 7.8 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor PAT1 PF09770.9 RUS72020.1 - 1.8 6.8 22.6 2.4 6.3 22.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RBP_receptor PF14752.6 RUS72021.1 - 2.1e-66 224.8 6.0 2.4e-66 224.6 6.0 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor Caleosin PF05042.13 RUS72021.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Caleosin related protein Chromate_transp PF02417.15 RUS72021.1 - 3.7 7.7 13.4 6.7 6.8 13.4 1.4 1 0 0 1 1 1 0 Chromate transporter RBP_receptor PF14752.6 RUS72022.1 - 3.3e-36 125.1 3.8 3.8e-36 124.9 3.8 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor MADF_DNA_bdg PF10545.9 RUS72024.1 - 1.5e-16 60.4 1.0 2.7e-16 59.6 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF573 PF04504.14 RUS72024.1 - 0.035 14.8 0.6 0.035 14.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 GDA1_CD39 PF01150.17 RUS72025.1 - 1.9e-93 313.5 0.5 2.7e-93 312.9 0.5 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ubiquitin PF00240.23 RUS72025.1 - 0.00025 20.7 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 RUS72025.1 - 0.0051 17.5 0.0 0.0098 16.6 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 RUS72025.1 - 0.042 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like GDA1_CD39 PF01150.17 RUS72026.1 - 1.8e-76 257.5 0.1 8.2e-69 232.3 0.0 2.1 1 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Cpn60_TCP1 PF00118.24 RUS72027.1 - 9.5e-161 535.7 4.8 1.1e-160 535.5 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tetraspanin PF00335.20 RUS72028.1 - 1.5e-45 155.7 12.8 1.8e-45 155.5 12.8 1.0 1 0 0 1 1 1 1 Tetraspanin family TMEM52 PF14979.6 RUS72028.1 - 0.037 13.9 0.2 0.09 12.7 0.2 1.6 1 0 0 1 1 1 0 Transmembrane 52 ABC2_membrane_3 PF12698.7 RUS72028.1 - 0.54 9.3 6.5 1.9 7.5 6.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein MgtE PF01769.16 RUS72028.1 - 1.9 8.9 8.4 4.3 7.7 5.6 2.2 2 0 0 2 2 2 0 Divalent cation transporter CD20 PF04103.15 RUS72028.1 - 3.8 7.6 18.0 47 4.0 18.0 2.3 1 1 0 1 1 1 0 CD20-like family FtsX PF02687.21 RUS72028.1 - 6.5 7.3 16.9 1.3 9.5 2.2 2.8 1 1 1 2 2 2 0 FtsX-like permease family DUF4064 PF13273.6 RUS72028.1 - 9.9 6.5 12.1 74 3.7 10.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Lectin_C PF00059.21 RUS72029.1 - 6.8e-08 33.2 0.4 6e-07 30.2 0.1 2.4 2 1 0 2 2 2 1 Lectin C-type domain YojJ PF10372.9 RUS72029.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus BORCS7 PF16088.5 RUS72030.1 - 1.3e-26 92.9 4.2 1.3e-26 92.8 4.2 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Phage_CP76 PF06892.11 RUS72030.1 - 0.067 12.7 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) adh_short PF00106.25 RUS72031.1 - 0.00043 19.8 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF2608 PF11019.8 RUS72032.1 - 0.35 10.3 2.1 1.8 8.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) PHD_2 PF13831.6 RUS72033.1 - 7.1e-06 25.5 4.0 1.4e-05 24.5 4.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS72033.1 - 1.3e-05 25.0 5.2 2.6e-05 24.0 5.2 1.5 1 0 0 1 1 1 1 PHD-finger Tnp_22_trimer PF17489.2 RUS72034.1 - 0.0098 15.8 1.5 0.085 12.8 0.1 2.7 2 1 1 3 3 3 1 L1 transposable element trimerization domain Matrilin_ccoil PF10393.9 RUS72034.1 - 0.031 14.1 4.1 0.25 11.2 0.1 3.1 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin GPS2_interact PF15784.5 RUS72034.1 - 0.051 14.0 0.9 0.097 13.1 0.9 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2205 PF10224.9 RUS72034.1 - 0.067 13.2 0.8 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Prominin PF05478.11 RUS72034.1 - 0.073 11.0 0.0 0.084 10.8 0.0 1.0 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 RUS72034.1 - 0.078 13.5 0.3 0.15 12.7 0.3 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Med9 PF07544.13 RUS72034.1 - 0.11 12.6 0.7 0.54 10.4 0.4 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.12 RUS72034.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 RUS72034.1 - 0.33 11.0 2.2 5.3 7.1 0.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 RUS72034.1 - 0.56 10.2 2.5 3.4 7.7 0.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit ABC_tran PF00005.27 RUS72035.1 - 0.002 18.6 0.0 0.0055 17.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Smg8_Smg9 PF10220.9 RUS72035.1 - 0.011 14.2 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 MMR_HSR1 PF01926.23 RUS72035.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 RUS72035.1 - 0.13 12.2 0.0 0.69 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Extensin_2 PF04554.13 RUS72037.1 - 1.4 9.1 16.4 56 3.9 10.3 4.7 1 1 1 2 2 2 0 Extensin-like region Sirohm_synth_M PF14824.6 RUS72037.1 - 2.2 7.8 9.6 2e+02 1.6 0.0 5.9 6 0 0 6 6 6 0 Sirohaem biosynthesis protein central SOBP PF15279.6 RUS72038.1 - 2.5e-59 202.5 15.4 2.5e-59 202.5 15.4 2.4 3 0 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.14 RUS72038.1 - 0.00034 20.5 10.4 0.1 12.5 3.1 2.6 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Aminotran_5 PF00266.19 RUS72039.1 - 2.8e-22 79.2 0.0 4.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RUS72039.1 - 0.0011 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RUS72039.1 - 0.053 12.8 0.1 0.17 11.2 0.1 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 RUS72039.1 - 0.088 11.3 0.0 0.22 10.0 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Folliculin PF11704.8 RUS72040.1 - 0.00018 21.5 0.1 0.00018 21.5 0.1 2.1 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport eIF-1a PF01176.19 RUS72041.1 - 4.2e-21 74.5 0.1 5.9e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 EF-hand_6 PF13405.6 RUS72042.1 - 0.00023 20.9 1.4 0.0018 18.0 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS72042.1 - 0.21 11.2 2.1 0.21 11.2 0.1 2.0 2 0 0 2 2 2 0 EF hand OATP PF03137.20 RUS72043.1 - 2.6e-89 300.0 10.0 3.1e-89 299.7 10.0 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS72043.1 - 3.6e-15 55.8 21.8 5.7e-13 48.5 7.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS72043.1 - 7.1e-07 29.2 4.2 1.6e-06 28.1 4.2 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS72043.1 - 0.006 16.6 2.1 0.013 15.5 2.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF3341 PF11821.8 RUS72043.1 - 0.12 12.0 4.5 2.5 7.7 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) CRAL_TRIO PF00650.20 RUS72045.1 - 2.7e-19 69.4 0.0 3.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RUS72045.1 - 2.7e-06 27.5 0.1 5.8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UCR_14kD PF02271.16 RUS72046.1 - 4.9e-34 116.3 1.2 7.3e-34 115.7 1.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HetR_C PF18460.1 RUS72046.1 - 0.15 12.0 1.9 0.31 11.0 1.9 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain CARD_2 PF16739.5 RUS72047.1 - 0.0011 18.8 0.6 0.0028 17.6 0.1 1.9 2 0 0 2 2 2 1 Caspase recruitment domain 7tm_1 PF00001.21 RUS72049.1 - 9.7e-18 64.4 8.6 1.4e-17 63.9 8.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ras PF00071.22 RUS72050.1 - 1.4e-26 93.1 0.0 5e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS72050.1 - 5.8e-08 33.0 0.0 8.9e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72050.1 - 0.0013 18.2 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS72050.1 - 0.0037 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS72050.1 - 0.018 14.9 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 RUS72050.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 RUS72050.1 - 0.053 12.7 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 RUS72050.1 - 0.13 12.6 0.0 0.54 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain fn3 PF00041.21 RUS72051.1 - 0.0021 18.4 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain FAD_binding_1 PF00667.20 RUS72053.1 - 4.9e-73 245.4 0.0 7e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RUS72053.1 - 1.4e-36 125.9 1.3 1.4e-36 125.9 1.3 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 RUS72053.1 - 1.5e-20 73.8 0.1 1.6e-19 70.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RUS72053.1 - 0.0063 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Glyco_tran_WecB PF03808.13 RUS72053.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family zf-RING_4 PF14570.6 RUS72053.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 RUS72054.1 - 1.3e-22 79.6 4.7 3.6e-06 27.6 1.5 5.8 5 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72054.1 - 1.5e-07 31.6 0.0 0.15 12.4 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RWD PF05773.22 RUS72055.1 - 1.3e-15 57.7 0.9 6.5e-15 55.4 0.0 2.6 2 0 0 2 2 2 1 RWD domain zf-RING_5 PF14634.6 RUS72055.1 - 5e-05 23.2 7.2 0.00021 21.2 7.3 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS72055.1 - 0.0012 19.1 14.1 0.0025 18.1 6.9 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RUS72055.1 - 0.069 13.0 4.4 0.4 10.6 4.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS72055.1 - 0.11 12.4 7.1 0.055 13.3 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS72055.1 - 0.84 9.4 12.6 0.064 13.0 6.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 RUS72055.1 - 0.94 9.3 3.9 2.2 8.2 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 RUS72055.1 - 1.7 8.6 6.9 0.29 11.0 0.2 3.2 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.6 RUS72055.1 - 2.2 8.4 8.2 0.33 11.0 1.8 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DNTTIP1_dimer PF18192.1 RUS72056.1 - 2.5e-22 79.0 0.3 6.7e-22 77.6 0.3 1.8 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain HetR_C PF18460.1 RUS72056.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain AAA_23 PF13476.6 RUS72056.1 - 1 9.8 5.5 2.4 8.6 5.5 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 RUS72057.1 - 6.6e-49 166.5 0.2 1.5e-48 165.3 0.1 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS72057.1 - 6e-22 78.1 0.1 2.4e-20 72.9 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS72057.1 - 1.8e-07 31.3 2.2 3.4e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 RUS72057.1 - 0.0011 18.0 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 HDA2-3 PF11496.8 RUS72057.1 - 0.0066 15.7 0.1 0.0066 15.7 0.1 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 RUS72057.1 - 0.016 14.8 1.5 0.084 12.5 0.0 2.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase TPR_2 PF07719.17 RUS72057.1 - 0.021 14.9 0.4 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS72057.1 - 0.024 14.5 1.2 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS72057.1 - 0.075 13.3 0.1 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS72057.1 - 0.17 12.0 0.0 0.61 10.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ephrin_rec_like PF07699.13 RUS72058.1 - 2.8e-08 33.4 1.6 2.8e-08 33.4 1.6 2.4 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 RUS72058.1 - 0.041 13.9 0.5 0.041 13.9 0.5 2.3 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS72058.1 - 6 7.4 9.3 1.2 9.6 0.4 3.2 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region Lectin_C PF00059.21 RUS72059.1 - 3.5e-15 56.7 0.1 5.2e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF3964 PF13107.6 RUS72059.1 - 0.061 13.7 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Sel1 PF08238.12 RUS72060.1 - 2.4e-17 63.0 14.9 8.2e-05 23.2 0.8 7.3 7 1 0 7 7 7 4 Sel1 repeat TPR_6 PF13174.6 RUS72060.1 - 0.00047 20.6 4.2 0.063 13.9 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS72060.1 - 0.0024 18.1 2.2 0.26 11.6 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS72060.1 - 0.0031 17.7 4.4 0.033 14.4 0.1 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RUS72060.1 - 0.0037 17.3 0.4 0.0037 17.3 0.4 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS72060.1 - 0.0089 16.5 1.5 0.21 12.1 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS72060.1 - 0.0098 15.7 13.2 0.028 14.3 0.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS72060.1 - 0.051 13.8 14.6 0.68 10.3 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS72060.1 - 0.053 13.6 0.7 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS72060.1 - 0.055 13.5 4.4 0.55 10.3 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS72060.1 - 0.064 13.9 1.7 22 5.8 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS72060.1 - 0.12 13.3 0.7 1.1 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS72060.1 - 0.14 12.0 2.3 16 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS72060.1 - 0.5 10.1 5.0 23 4.8 0.2 3.6 3 0 0 3 3 3 0 TPR repeat DUF1741 PF08427.10 RUS72061.1 - 5.8e-85 284.7 4.5 1.2e-84 283.6 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) adh_short PF00106.25 RUS72062.1 - 1.1e-43 149.0 0.7 1.8e-43 148.3 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS72062.1 - 4.5e-29 101.7 0.0 5.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS72062.1 - 6.3e-09 36.0 0.2 1e-08 35.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS72062.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 RUS72062.1 - 0.039 14.7 0.0 0.17 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF459 PF04311.13 RUS72062.1 - 0.048 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) GDP_Man_Dehyd PF16363.5 RUS72062.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Band_7 PF01145.25 RUS72063.1 - 9.2e-20 71.4 1.3 2.8e-18 66.5 0.1 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family SCP2 PF02036.17 RUS72063.1 - 5e-14 52.6 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RUS72063.1 - 0.015 15.5 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 RUS72063.1 - 0.024 15.0 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Sterol carrier protein domain UPF1_Zn_bind PF09416.10 RUS72064.1 - 8.5e-75 249.8 3.8 2.3e-74 248.4 2.9 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 RUS72064.1 - 1.5e-58 197.7 0.0 2.7e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS72064.1 - 3.5e-44 151.6 5.7 8.7e-24 84.7 1.5 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 RUS72064.1 - 4.9e-32 110.0 0.0 1.1e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 RUS72064.1 - 2e-12 47.2 0.0 8.7e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS72064.1 - 6.5e-10 39.5 0.0 1.8e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RUS72064.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 RUS72064.1 - 0.00029 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 RUS72064.1 - 0.00061 19.1 0.0 0.008 15.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 RUS72064.1 - 0.0039 17.0 0.0 3 7.5 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 RUS72064.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 RUS72064.1 - 0.0089 15.6 0.2 0.042 13.4 0.0 2.1 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 RUS72064.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 KaiC DEAD PF00270.29 RUS72064.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 RUS72064.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 RUS72064.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 RUS72064.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain p450 PF00067.22 RUS72065.1 - 2.4e-95 320.0 0.0 3.2e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_8 PF14278.6 RUS72065.1 - 0.21 11.7 0.5 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region 7tm_2 PF00002.24 RUS72066.1 - 4.3e-61 206.3 20.7 5.7e-61 205.9 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS72066.1 - 7.6e-15 55.0 4.5 7.6e-15 55.0 4.5 1.8 2 0 0 2 2 2 1 Hormone receptor domain Glycos_transf_2 PF00535.26 RUS72067.1 - 3.5e-27 95.3 0.0 6.7e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS72067.1 - 1.7e-09 38.0 0.1 3.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RUS72067.1 - 0.0001 21.9 0.1 0.00028 20.5 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Gelsolin PF00626.22 RUS72068.1 - 2.4e-44 149.1 0.8 8.2e-13 48.1 0.0 5.6 5 0 0 5 5 5 5 Gelsolin repeat LRR_8 PF13855.6 RUS72068.1 - 6.4e-33 112.3 42.1 4.9e-08 32.6 7.1 6.6 3 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 RUS72068.1 - 1.9e-27 94.9 53.7 3.7e-06 27.2 1.2 9.2 5 3 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS72068.1 - 0.003 17.9 36.9 14 6.7 0.2 11.1 11 1 0 11 11 11 2 Leucine Rich Repeat SRP-alpha_N PF04086.13 RUS72068.1 - 0.054 13.4 1.6 0.065 13.1 0.2 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2367 PF10164.9 RUS72069.1 - 1.2e-34 118.9 11.3 3.8e-34 117.3 11.3 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Rubredoxin_2 PF18073.1 RUS72069.1 - 0.13 12.0 3.3 7.4 6.4 0.8 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain WD40 PF00400.32 RUS72070.1 - 2.2e-37 126.4 4.0 1.5e-06 28.8 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72070.1 - 2e-13 50.5 0.4 9.1e-06 25.9 0.1 5.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS72070.1 - 6.6e-07 28.6 0.1 0.018 14.0 0.0 4.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS72070.1 - 1.5e-05 25.0 0.1 0.25 11.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RUS72070.1 - 8e-05 21.5 3.5 0.096 11.3 0.1 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS72070.1 - 0.00015 21.2 0.0 0.022 14.1 0.0 3.0 2 1 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 RUS72070.1 - 0.03 13.1 0.1 0.9 8.2 0.0 3.3 1 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 RUS72070.1 - 0.033 13.5 0.0 2.7 7.2 0.0 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 RUS72070.1 - 0.048 12.0 0.0 0.069 11.5 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 RUS72070.1 - 0.088 12.5 1.1 12 5.5 0.0 3.1 2 1 2 4 4 4 0 TUP1-like enhancer of split PQQ_3 PF13570.6 RUS72070.1 - 0.15 12.6 0.1 5.4 7.6 0.0 3.5 4 1 1 5 5 5 0 PQQ-like domain RVT_1 PF00078.27 RUS72071.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Fe_hyd_lg_C PF02906.14 RUS72072.1 - 2.4e-77 259.9 0.0 3.7e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 RUS72072.1 - 4.9e-05 23.3 0.2 0.00011 22.2 0.2 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit WD40 PF00400.32 RUS72073.1 - 6.6e-20 71.1 8.6 5.6e-05 23.8 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RUS72073.1 - 3.2e-12 46.5 0.0 4.7e-11 42.8 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 RUS72073.1 - 1.3e-05 25.2 0.2 9.7e-05 22.3 0.1 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RUS72073.1 - 0.00029 21.1 0.6 0.13 12.6 0.1 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 RUS72073.1 - 1 7.4 6.3 1.6 6.8 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 RUS72073.1 - 1.2 8.9 5.4 2.7 7.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) OAD_gamma PF04277.13 RUS72073.1 - 1.2 9.8 5.3 8.5 7.0 0.3 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.6 RUS72073.1 - 4 7.1 8.5 0.43 10.2 3.3 1.9 2 0 0 2 2 2 0 FAM176 family MRNIP PF15749.5 RUS72073.1 - 5.6 7.7 7.6 0.56 11.0 2.4 1.9 2 0 0 2 2 2 0 MRN-interacting protein CRA PF06589.11 RUS72073.1 - 5.9 7.0 6.1 23 5.1 0.1 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) CENP-B_dimeris PF09026.10 RUS72073.1 - 8.8 6.8 10.1 0.45 10.9 3.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CCDC154 PF15450.6 RUS72074.1 - 5.7e-34 117.6 83.1 5.7e-34 117.6 83.1 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 154 UvrB PF12344.8 RUS72074.1 - 0.23 11.4 3.2 24 4.9 0.1 3.7 3 1 0 3 3 3 0 Ultra-violet resistance protein B IML1 PF12257.8 RUS72075.1 - 4.9 6.2 14.8 16 4.5 0.9 3.3 1 1 3 4 4 4 0 Vacuolar membrane-associated protein Iml1 AA_permease_2 PF13520.6 RUS72076.1 - 3.2e-50 171.2 55.9 3.7e-50 171.0 55.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS72076.1 - 1.6e-25 89.7 52.8 2.9e-25 88.8 52.8 1.4 1 1 0 1 1 1 1 Amino acid permease An_peroxidase PF03098.15 RUS72077.1 - 2.9e-173 577.2 0.1 3.3e-173 577.0 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase ATP-synt_ab_Xtn PF16886.5 RUS72077.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension 7TM_GPCR_Srx PF10328.9 RUS72078.1 - 6.9e-08 32.4 8.0 6.9e-08 32.4 8.0 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS72078.1 - 1.5e-07 31.0 15.4 0.00011 21.6 1.4 2.8 1 1 2 3 3 3 2 7 transmembrane receptor (rhodopsin family) SBF PF01758.16 RUS72078.1 - 0.0091 15.7 1.9 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family MNSV_P7B PF06692.11 RUS72078.1 - 0.066 13.2 1.8 0.19 11.7 1.8 1.8 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Peptidase_C1 PF00112.23 RUS72079.1 - 1.2e-66 224.9 4.8 1.6e-66 224.5 4.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RUS72079.1 - 1.3e-09 37.8 0.0 2.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS72079.1 - 7.5e-05 21.7 0.8 0.028 13.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ZU5 PF00791.20 RUS72080.1 - 7.8e-10 39.0 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain SPACA9 PF15120.6 RUS72080.1 - 0.029 14.2 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Death PF00531.22 RUS72080.1 - 0.095 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Death domain Laminin_EGF PF00053.24 RUS72081.1 - 7.3e-122 397.4 372.5 8.1e-12 45.1 13.4 20.2 19 1 1 20 20 19 19 Laminin EGF domain Laminin_G_2 PF02210.24 RUS72081.1 - 9e-91 301.0 2.5 1.9e-20 73.7 0.1 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 RUS72081.1 - 2.7e-88 292.9 0.8 3.2e-17 63.0 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 RUS72081.1 - 5.6e-66 222.5 5.1 9.3e-65 218.5 0.0 3.2 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 RUS72081.1 - 5.3e-56 188.3 0.6 3.5e-33 114.4 0.5 2.6 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_G_3 PF13385.6 RUS72081.1 - 9.4e-15 55.1 1.0 0.0055 16.9 0.0 5.3 5 0 0 5 5 5 4 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 RUS72081.1 - 1.1e-06 28.6 6.9 1.1e-06 28.6 6.9 5.1 3 1 2 5 5 5 2 Laminin Domain II Laminin_I PF06008.14 RUS72081.1 - 1.4e-06 28.3 15.4 1.4e-06 28.3 15.4 3.2 1 1 2 3 3 2 1 Laminin Domain I DUF948 PF06103.11 RUS72081.1 - 0.25 11.6 21.9 0.051 13.8 0.2 5.3 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) Bac_rhamnosid PF05592.11 RUS72081.1 - 0.3 11.1 1.1 2.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain TAN PF11640.8 RUS72081.1 - 0.64 10.1 6.7 0.13 12.4 2.5 1.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Methyltransf_14 PF08484.11 RUS72081.1 - 7.9 6.3 6.9 19 5.0 0.5 3.1 3 0 0 3 3 3 0 C-methyltransferase C-terminal domain Tubulin PF00091.25 RUS72082.1 - 1.2e-68 231.2 0.0 1.7e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS72082.1 - 3.7e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS72082.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain LRR_4 PF12799.7 RUS72083.1 - 5.3e-16 58.5 29.3 8.2e-07 29.3 7.9 5.5 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS72083.1 - 2.5e-11 43.2 26.2 0.0016 18.2 8.5 4.7 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 RUS72083.1 - 7.9e-08 32.0 7.8 0.00032 20.3 0.6 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 RUS72083.1 - 0.12 12.5 30.3 3.8 7.8 1.1 7.9 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 RUS72083.1 - 6.1 7.8 25.6 31 5.7 0.0 7.5 6 2 1 7 7 7 0 Leucine Rich Repeat Fasciclin PF02469.22 RUS72084.1 - 1.7e-52 177.0 0.0 1.4e-25 90.0 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 RUS72085.1 - 7.3e-45 152.3 0.0 1.5e-24 86.6 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Ion_trans PF00520.31 RUS72086.1 - 3.1e-20 72.4 16.9 5.7e-20 71.6 16.9 1.4 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RUS72086.1 - 1.6e-17 63.3 0.1 3.3e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RUS72086.1 - 0.0047 16.9 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 Ion channel Transglut_core PF01841.19 RUS72087.1 - 0.0073 16.7 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_C2 PF00648.21 RUS72090.1 - 8.6e-100 333.6 0.0 1.1e-99 333.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS72090.1 - 1.2e-25 90.4 0.0 2.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III Ig_3 PF13927.6 RUS72091.1 - 3.5e-14 53.2 0.0 1.2e-07 32.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS72091.1 - 3e-13 49.6 0.0 6.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Peptidase_C14 PF00656.22 RUS72091.1 - 2.2e-10 40.9 0.1 3.4e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Caspase domain Ig_2 PF13895.6 RUS72091.1 - 3.2e-06 27.4 0.1 0.00024 21.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS72091.1 - 0.00085 19.5 1.6 0.71 10.1 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 RUS72091.1 - 0.0082 16.3 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 RUS72091.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 Ion_trans PF00520.31 RUS72092.1 - 3.8e-31 108.2 23.0 2.5e-30 105.5 22.5 2.1 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS72092.1 - 3e-22 78.8 0.0 9.9e-22 77.1 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS72092.1 - 9.3e-09 35.1 10.2 9.3e-09 35.1 10.2 2.4 2 0 0 2 2 2 1 Ion channel 7tm_1 PF00001.21 RUS72094.1 - 9.7e-07 28.4 7.0 1.4e-06 27.9 7.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72094.1 - 2.1e-05 24.3 3.9 2.9e-05 23.8 3.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CDC45 PF02724.14 RUS72094.1 - 0.0005 18.5 9.2 0.00062 18.2 9.2 1.1 1 0 0 1 1 1 1 CDC45-like protein 7TM_GPCR_Srv PF10323.9 RUS72094.1 - 0.014 14.8 5.7 0.019 14.4 5.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Astro_capsid_p PF12226.8 RUS72094.1 - 0.24 10.5 14.4 0.3 10.2 14.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CobT PF06213.12 RUS72094.1 - 0.45 9.9 13.7 0.59 9.5 13.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 RUS72094.1 - 0.76 8.9 40.8 1.1 8.4 40.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS72094.1 - 3.6 5.7 25.9 4.6 5.3 25.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS72094.1 - 7.6 5.9 23.5 9.7 5.5 23.5 1.1 1 0 0 1 1 1 0 SDA1 7TM_GPCR_Srw PF10324.9 RUS72095.1 - 3.5e-16 59.4 5.4 3.9e-16 59.2 5.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RUS72095.1 - 2.1e-05 24.0 3.7 2.8e-05 23.6 3.3 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Sru PF10322.9 RUS72095.1 - 0.0017 17.7 1.2 0.0017 17.7 1.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru O-ag_pol_Wzy PF14296.6 RUS72095.1 - 0.0041 15.8 2.3 0.0046 15.7 2.3 1.0 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy 7tm_1 PF00001.21 RUS72095.1 - 0.0045 16.4 3.8 0.0045 16.4 3.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TctB PF07331.11 RUS72095.1 - 0.011 16.0 0.2 0.013 15.7 0.2 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family CitMHS PF03600.16 RUS72095.1 - 0.059 12.6 2.1 0.07 12.3 2.1 1.2 1 1 0 1 1 1 0 Citrate transporter DUF3671 PF12420.8 RUS72095.1 - 0.78 9.8 3.7 4.6 7.4 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function Ldh_1_C PF02866.18 RUS72097.1 - 9.8e-51 172.0 0.0 1.4e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RUS72097.1 - 1.4e-27 96.6 1.1 1.7e-27 96.3 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain DSPc PF00782.20 RUS72098.1 - 9.6e-23 80.5 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RUS72098.1 - 1.1e-08 35.6 0.0 2.7e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain CDK2AP PF09806.9 RUS72099.1 - 3.1 7.8 22.0 0.72 9.9 4.0 2.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PHB_acc_N PF07879.11 RUS72100.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain MULE PF10551.9 RUS72101.1 - 6.7e-16 58.5 0.2 1.4e-15 57.4 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5575 PF17738.1 RUS72101.1 - 5.6e-07 28.9 0.2 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5575) FAR1 PF03101.15 RUS72101.1 - 2.9e-06 27.9 0.0 6.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_ISL3 PF01610.17 RUS72101.1 - 3.4e-05 23.7 5.5 0.00057 19.7 1.1 2.4 1 1 1 2 2 2 2 Transposase CotH PF08757.11 RUS72101.1 - 0.039 13.5 0.8 0.062 12.8 0.3 1.7 2 0 0 2 2 2 0 CotH kinase protein DUF5315 PF17242.2 RUS72101.1 - 0.052 13.4 2.5 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) DUF1959 PF09218.10 RUS72101.1 - 0.07 13.3 0.9 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Ribosomal_S8e PF01201.22 RUS72102.1 - 5.2e-54 182.1 0.8 6.2e-54 181.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e RT_RNaseH_2 PF17919.1 RUS72103.1 - 1.6e-29 101.8 0.0 5e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS72103.1 - 3.1e-21 75.9 0.0 5.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS72103.1 - 9.8e-21 74.2 0.0 2.5e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 RUS72103.1 - 1.8e-18 66.8 0.0 4.8e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 RUS72103.1 - 3.8e-05 23.4 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 RUS72103.1 - 0.015 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_1 PF03184.19 RUS72105.1 - 1.9e-09 37.4 1.0 4.3e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 RUS72105.1 - 1.3e-05 24.9 0.1 2.4e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KKLCAg1 PF15204.6 RUS72105.1 - 0.042 13.9 0.6 0.11 12.6 0.7 1.6 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Pkinase_Tyr PF07714.17 RUS72106.1 - 5.1e-48 163.6 0.9 2.3e-35 122.1 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS72106.1 - 6.7e-43 147.0 0.1 1e-32 113.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain LIM PF00412.22 RUS72106.1 - 1.5e-27 95.6 17.1 7.9e-16 58.0 2.5 2.5 2 0 0 2 2 2 2 LIM domain PDZ_6 PF17820.1 RUS72106.1 - 4e-06 26.6 0.1 8.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS72106.1 - 1.4e-05 25.4 0.1 5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Kdo PF06293.14 RUS72106.1 - 0.00023 20.6 0.1 0.00042 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS72106.1 - 0.0039 17.2 0.1 0.0073 16.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PDZ_2 PF13180.6 RUS72106.1 - 0.0061 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RIO1 PF01163.22 RUS72106.1 - 0.0065 16.1 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family DUF2040 PF09745.9 RUS72107.1 - 3.9e-37 127.0 20.0 3.9e-37 127.0 20.0 3.0 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) EMP24_GP25L PF01105.24 RUS72108.1 - 2.2e-46 158.1 0.2 2.9e-46 157.7 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD mit_SMPDase PF14724.6 RUS72110.1 - 1.2e-32 112.8 0.0 1.5e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Putative_PNPOx PF01243.20 RUS72112.1 - 2.2e-26 91.9 0.0 3.7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 RUS72112.1 - 5.9e-17 61.5 0.5 1.1e-16 60.6 0.5 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 RUS72112.1 - 1e-06 29.3 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 RUS72112.1 - 1.1e-05 25.1 0.1 1.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Pyridox_ox_2 PF12900.7 RUS72112.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase KdpC PF02669.15 RUS72112.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain NAGidase PF07555.13 RUS72113.1 - 7.1e-80 268.5 0.0 1.1e-79 267.8 0.0 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase TGF_beta PF00019.20 RUS72114.1 - 2.5e-22 79.8 0.4 9.8e-22 77.9 0.4 2.1 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS72114.1 - 1.1e-12 48.2 0.8 1.1e-12 48.2 0.8 2.1 2 1 0 2 2 2 1 TGF-beta propeptide PA26 PF04636.13 RUS72114.1 - 0.85 8.5 8.5 1.3 7.8 8.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MFS_1 PF07690.16 RUS72115.1 - 9.9e-20 70.7 20.0 1.3e-06 27.6 4.0 4.1 2 1 2 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.6 RUS72115.1 - 5.2e-09 35.2 0.7 5.2e-09 35.2 0.7 4.3 5 0 0 5 5 5 2 MFS/sugar transport protein DUF3169 PF11368.8 RUS72115.1 - 0.076 12.5 0.0 0.076 12.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MFS_1_like PF12832.7 RUS72115.1 - 0.36 9.6 0.0 0.36 9.6 0.0 4.4 3 1 1 4 4 4 0 MFS_1 like family PUCC PF03209.15 RUS72115.1 - 4.5 6.2 13.7 0.015 14.4 2.9 2.3 3 1 0 3 3 3 0 PUCC protein LRR_8 PF13855.6 RUS72116.1 - 3.1e-61 203.0 85.4 7.9e-10 38.4 8.4 12.1 5 3 5 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 RUS72116.1 - 1.7e-44 149.0 93.7 4e-05 23.9 0.2 13.9 7 2 11 18 18 18 17 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS72116.1 - 7.1e-10 38.7 46.7 0.001 18.6 3.3 7.2 1 1 5 7 7 7 6 Leucine-rich repeat Death PF00531.22 RUS72116.1 - 1.9e-05 24.8 0.1 0.0001 22.4 0.0 2.4 2 0 0 2 2 2 1 Death domain CSTF_C PF14304.6 RUS72116.1 - 0.0036 16.8 1.9 2.9 7.5 0.0 3.7 3 0 0 3 3 3 2 Transcription termination and cleavage factor C-terminal RsmF_methylt_CI PF17126.5 RUS72116.1 - 0.043 13.9 1.5 27 4.9 0.0 5.8 5 2 1 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain LRR_5 PF13306.6 RUS72116.1 - 0.21 11.6 12.5 0.95 9.4 0.4 4.5 4 2 2 6 6 6 0 BspA type Leucine rich repeat region (6 copies) DUF3475 PF11961.8 RUS72116.1 - 0.31 11.1 3.6 1.7 8.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3475) Ank_2 PF12796.7 RUS72117.1 - 9.6e-15 55.0 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72117.1 - 6.7e-12 45.7 0.1 7.9e-08 32.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS72117.1 - 6.3e-11 42.2 0.2 5.7e-05 23.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS72117.1 - 1.3e-09 38.2 0.1 6e-08 32.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72117.1 - 3.3e-09 36.2 0.0 4.1e-05 23.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ribosomal_L41 PF05162.13 RUS72117.1 - 9.3e-07 28.8 30.6 1.6e-06 28.0 30.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 DUF3021 PF11457.8 RUS72117.1 - 0.72 10.2 4.7 1.2 9.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Ras PF00071.22 RUS72118.1 - 2e-32 112.1 0.1 2.3e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72118.1 - 7.1e-23 81.1 0.1 1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72118.1 - 7.1e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS72118.1 - 4.7e-07 29.9 0.0 8.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS72118.1 - 0.00059 19.2 0.2 0.0011 18.4 0.2 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 RUS72118.1 - 0.0012 19.1 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RUS72118.1 - 0.0028 17.6 0.3 0.029 14.3 0.3 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RUS72118.1 - 0.0055 17.1 0.0 0.097 13.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 RUS72118.1 - 0.04 13.4 0.1 0.058 12.8 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 RUS72118.1 - 0.041 13.0 0.0 0.09 11.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RUS72118.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Toxin_15 PF07906.13 RUS72118.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region TniB PF05621.11 RUS72118.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein zf-Sec23_Sec24 PF04810.15 RUS72119.1 - 0.00028 20.9 0.2 0.00089 19.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger ARS2 PF04959.13 RUS72119.1 - 0.0094 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 RUS72119.1 - 0.035 14.9 0.9 0.035 14.9 0.9 3.4 3 1 1 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 RUS72119.1 - 0.037 14.1 1.7 0.31 11.1 0.3 2.6 2 1 0 2 2 2 0 BED zinc finger zf-met PF12874.7 RUS72119.1 - 0.054 13.9 1.3 0.2 12.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS72119.1 - 0.056 13.7 0.4 0.2 12.0 0.4 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TIM21 PF08294.11 RUS72119.1 - 0.068 13.0 0.6 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 TIM21 DUF5465 PF17553.2 RUS72119.1 - 0.08 13.5 1.7 0.18 12.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5465) zf-H2C2_2 PF13465.6 RUS72119.1 - 0.13 12.7 0.5 0.55 10.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 RUS72119.1 - 1.3 9.7 5.5 0.2 12.2 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_ribbon_17 PF17120.5 RUS72120.1 - 7.9e-12 44.6 12.2 7.9e-12 44.6 12.2 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 RUS72120.1 - 1.1e-11 45.1 21.7 0.00022 21.9 0.5 6.1 5 0 0 5 5 5 4 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 RUS72120.1 - 7.6e-07 29.4 4.2 7.6e-07 29.4 4.2 2.7 1 1 1 2 2 2 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 RUS72120.1 - 0.016 15.5 0.8 0.37 11.1 0.0 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4059 PF13268.6 RUS72121.1 - 0.021 15.2 0.1 1.3 9.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) COesterase PF00135.28 RUS72122.1 - 2e-138 462.5 0.0 2.5e-138 462.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS72122.1 - 0.00032 20.6 0.1 0.0013 18.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold LST1 PF05083.13 RUS72122.1 - 0.19 12.0 0.1 0.45 10.8 0.1 1.6 1 0 0 1 1 1 0 LST-1 protein SpoIIIAH PF12685.7 RUS72123.1 - 1.7 8.4 15.2 0.082 12.7 0.4 2.3 1 1 1 2 2 2 0 SpoIIIAH-like protein ArfGap PF01412.18 RUS72125.1 - 9.9e-35 119.1 0.1 3.3e-34 117.4 0.1 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 RUS72125.1 - 1.5e-32 112.2 4.6 5.4e-14 52.6 0.1 4.7 4 0 0 4 4 4 3 PH domain PH_11 PF15413.6 RUS72125.1 - 1.6e-09 38.1 13.8 2.3e-05 24.8 1.4 4.9 4 2 0 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.6 RUS72125.1 - 6.3e-08 32.7 0.4 0.0022 18.1 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 RUS72125.1 - 7.6e-08 32.5 2.5 0.00022 21.4 0.1 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain RhoGAP PF00620.27 RUS72125.1 - 4.6e-05 23.3 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RRM_1 PF00076.22 RUS72127.1 - 9e-76 249.7 0.4 6.4e-17 61.1 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS72127.1 - 2.5e-16 59.4 2.1 0.00043 19.9 0.0 5.0 1 1 4 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RUS72127.1 - 2e-10 40.6 1.1 0.034 14.2 0.1 4.4 3 1 1 4 4 4 4 Limkain b1 Nup35_RRM PF05172.13 RUS72127.1 - 1.1e-05 25.4 5.1 0.14 12.1 0.0 5.0 4 1 1 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RUS72127.1 - 0.00027 21.0 0.4 50 4.1 0.0 5.3 5 2 0 5 5 5 0 RNA recognition motif RNA_bind PF08675.11 RUS72127.1 - 0.00043 20.3 0.3 0.29 11.2 0.0 4.4 5 1 0 5 5 5 1 RNA binding domain RRM_occluded PF16842.5 RUS72127.1 - 0.023 14.6 0.0 0.51 10.2 0.0 3.2 4 0 0 4 4 4 0 Occluded RNA-recognition motif PhetRS_B1 PF18262.1 RUS72127.1 - 0.027 14.7 0.1 56 4.1 0.0 4.1 4 0 0 4 4 4 0 Phe-tRNA synthetase beta subunit B1 domain UPF0121 PF03661.13 RUS72128.1 - 1.6e-89 299.5 17.4 1.8e-89 299.3 17.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Alpha_adaptinC2 PF02883.20 RUS72129.1 - 9.9e-34 116.0 3.2 2.2e-33 114.9 3.2 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Adaptin_N PF01602.20 RUS72129.1 - 5.3e-23 81.4 1.2 6.5e-23 81.1 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Pax7 PF12360.8 RUS72129.1 - 0.031 14.5 0.8 0.031 14.5 0.8 2.3 2 0 0 2 2 2 0 Paired box protein 7 Pesticin PF16754.5 RUS72129.1 - 0.098 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term DDE_1 PF03184.19 RUS72130.1 - 4.8e-12 45.9 0.5 2.8e-09 36.9 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.6 RUS72130.1 - 3.2e-06 26.9 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 RUS72130.1 - 5.1e-06 26.1 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 RUS72130.1 - 0.029 14.2 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 RUS72130.1 - 0.033 14.3 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 RUS72130.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 RUS72130.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF917 PF06032.12 RUS72130.1 - 0.19 10.5 0.0 0.36 9.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF917) USP19_linker PF16602.5 RUS72131.1 - 0.24 12.0 3.9 0.22 12.1 0.9 2.4 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase RVT_1 PF00078.27 RUS72132.1 - 0.00015 21.3 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_IV PF05190.18 RUS72132.1 - 0.021 15.2 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV Glyco_hydro_57 PF03065.15 RUS72132.1 - 0.057 12.6 0.1 0.076 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 H_lectin PF09458.10 RUS72133.1 - 1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 H-type lectin domain Pkinase_Tyr PF07714.17 RUS72134.1 - 4.4e-30 104.8 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS72134.1 - 9.8e-19 67.7 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EMP24_GP25L PF01105.24 RUS72135.1 - 1.1e-10 41.7 0.2 2.1e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Nop14 PF04147.12 RUS72135.1 - 0.00012 20.5 22.9 0.00012 20.5 22.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS72135.1 - 0.00018 21.1 20.8 0.00018 21.1 20.8 1.2 1 0 0 1 1 1 1 SDA1 DUF2076 PF09849.9 RUS72135.1 - 0.0014 18.8 19.4 0.0019 18.3 19.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.14 RUS72135.1 - 0.0098 14.2 18.1 0.012 14.0 18.1 1.2 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 RUS72135.1 - 0.034 13.5 19.7 0.04 13.3 19.7 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 RUS72135.1 - 5.9 5.5 8.9 6.5 5.4 8.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3K_1B_p101 PF10486.9 RUS72135.1 - 6 4.5 5.3 5.4 4.7 5.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EMP24_GP25L PF01105.24 RUS72136.1 - 8e-54 182.3 1.1 9.8e-54 182.1 1.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF658 PF04936.12 RUS72136.1 - 0.053 13.3 0.2 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF658) Actin PF00022.19 RUS72137.1 - 1.4e-49 168.8 0.0 6.4e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 RUS72137.1 - 0.079 13.2 2.3 0.15 12.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TIMP PF00965.17 RUS72138.1 - 0.00014 21.7 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase zf-RING_UBOX PF13445.6 RUS72138.1 - 0.035 14.1 0.3 0.076 13.1 0.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Lectin_C PF00059.21 RUS72139.1 - 5.8e-15 56.0 2.5 1.1e-14 55.0 2.5 1.5 1 0 0 1 1 1 1 Lectin C-type domain V-set PF07686.17 RUS72139.1 - 2.5e-07 30.9 0.2 9.1e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain UL45 PF05473.12 RUS72139.1 - 0.0052 16.5 1.7 0.015 14.9 1.7 1.7 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Ig_3 PF13927.6 RUS72139.1 - 0.039 14.5 0.8 0.088 13.4 0.1 2.0 2 1 0 2 2 2 0 Immunoglobulin domain DUF2808 PF10989.8 RUS72139.1 - 0.05 13.6 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) TIMP PF00965.17 RUS72140.1 - 1.3e-06 28.4 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Baculo_PEP_C PF04513.12 RUS72141.1 - 1.5e-08 34.8 10.2 0.017 15.1 0.3 4.2 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1598 PF07643.11 RUS72141.1 - 1.6e-05 25.0 16.1 6.3 7.1 0.3 8.2 1 1 7 9 9 9 2 Protein of unknown function (DUF1598) DUF3575 PF12099.8 RUS72141.1 - 0.00067 19.0 0.7 2.2 7.5 0.0 4.1 1 1 2 4 4 4 1 Protein of unknown function (DUF3575) Apolipoprotein PF01442.18 RUS72141.1 - 0.0016 18.4 18.0 0.062 13.2 6.5 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain IL11 PF07400.11 RUS72141.1 - 0.019 14.6 29.6 1.7 8.3 10.2 4.7 1 1 2 3 3 3 0 Interleukin 11 Remorin_C PF03763.13 RUS72141.1 - 0.1 12.5 40.7 2 8.4 6.7 4.9 1 1 4 5 5 5 0 Remorin, C-terminal region Phasin PF05597.11 RUS72141.1 - 0.22 11.6 24.6 14 5.7 2.2 4.3 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GCV_T_C PF08669.11 RUS72141.1 - 8.9 6.3 6.7 84 3.2 0.4 4.6 2 2 1 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain TIMP PF00965.17 RUS72142.1 - 0.00025 20.9 0.0 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase UPF0236 PF06782.11 RUS72142.1 - 0.02 13.5 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) MlaD PF02470.20 RUS72142.1 - 0.065 13.5 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 MlaD protein Cyclin_N PF00134.23 RUS72143.1 - 1.6e-08 34.4 1.9 2.8e-05 23.9 0.3 3.0 2 0 0 2 2 2 2 Cyclin, N-terminal domain Proteasome PF00227.26 RUS72144.1 - 4.1e-52 176.4 0.0 5.4e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS72144.1 - 6e-14 51.4 0.1 1.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HSF_DNA-bind PF00447.17 RUS72145.1 - 1.7e-09 38.2 0.4 5.4e-09 36.6 0.4 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4368 PF14287.6 RUS72145.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) FPN1 PF06963.12 RUS72146.1 - 2.6e-132 441.5 14.5 3.1e-132 441.2 14.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) COX14 PF14880.6 RUS72146.1 - 0.046 13.6 0.4 0.3 11.0 0.4 2.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RIIa PF02197.17 RUS72147.1 - 0.0055 16.3 0.0 0.0055 16.3 0.0 2.1 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit Lectin_leg-like PF03388.13 RUS72148.1 - 2.8e-93 311.5 0.6 3.5e-93 311.2 0.6 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RUS72148.1 - 5.9e-11 42.8 1.7 7.7e-11 42.4 1.7 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 RUS72148.1 - 0.015 14.8 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain LapA_dom PF06305.11 RUS72148.1 - 0.2 11.5 0.9 0.53 10.1 0.9 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-RING_5 PF14634.6 RUS72149.1 - 6.8e-08 32.4 10.3 1.2e-07 31.5 10.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Phage_GPO PF05929.11 RUS72149.1 - 0.00016 21.4 1.6 0.00021 21.0 1.6 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DASH_Duo1 PF08651.10 RUS72149.1 - 0.00056 19.6 1.5 0.00093 18.9 1.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 TACC_C PF05010.14 RUS72149.1 - 0.0014 18.5 7.7 0.0019 18.0 7.7 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EcoR124_C PF12008.8 RUS72149.1 - 0.0094 15.6 0.8 0.013 15.2 0.8 1.2 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal FapA PF03961.13 RUS72149.1 - 0.032 12.8 1.9 0.038 12.6 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mitofilin PF09731.9 RUS72149.1 - 0.058 12.2 9.0 0.074 11.9 9.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Prok-RING_4 PF14447.6 RUS72149.1 - 0.13 12.2 8.7 0.29 11.0 8.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Aminotran_4 PF01063.19 RUS72149.1 - 0.15 11.9 0.1 0.21 11.4 0.1 1.1 1 0 0 1 1 1 0 Amino-transferase class IV DUF4298 PF14131.6 RUS72149.1 - 0.21 11.6 4.9 0.063 13.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Exonuc_VII_L PF02601.15 RUS72149.1 - 0.22 11.1 3.1 0.26 10.8 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 RUS72149.1 - 0.22 10.7 5.8 0.31 10.2 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Sec1 PF00995.23 RUS72149.1 - 0.94 8.6 5.4 1.2 8.2 5.4 1.1 1 0 0 1 1 1 0 Sec1 family zf-C3HC4 PF00097.25 RUS72149.1 - 1.3 9.0 12.0 4.1 7.3 11.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 RUS72149.1 - 2.3 6.0 6.8 2.9 5.7 6.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC PF00098.23 RUS72150.1 - 0.02 14.9 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 RUS72150.1 - 0.12 13.1 0.0 10 6.9 0.0 2.3 1 1 1 2 2 2 0 Aspartyl protease KTI12 PF08433.10 RUS72152.1 - 1.3e-17 64.2 0.5 1.5e-13 50.8 0.4 2.2 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 RUS72152.1 - 1.5e-09 38.1 0.0 3.8e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RUS72152.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 RUS72152.1 - 0.044 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 RUS72152.1 - 0.06 13.6 0.0 0.23 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RUS72152.1 - 0.25 11.9 1.9 4.5 7.8 0.5 3.0 2 1 0 2 2 2 0 AAA domain CUE PF02845.16 RUS72153.1 - 8.7e-11 41.3 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF5466 PF17554.2 RUS72153.1 - 0.22 11.8 0.2 5.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5466) G2BR PF18442.1 RUS72153.1 - 0.44 10.2 3.4 17 5.2 1.8 2.3 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) VEFS-Box PF09733.9 RUS72154.1 - 1.2e-48 164.5 0.1 1.5e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 VEFS-Box of polycomb protein AAA_19 PF13245.6 RUS72154.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Big_2 PF02368.18 RUS72155.1 - 2.3e-11 43.4 0.5 0.00082 19.2 0.0 4.9 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.6 RUS72155.1 - 0.027 14.2 1.8 43 3.9 0.0 5.5 5 1 1 6 6 6 0 Pilus formation protein N terminal region Podoplanin PF05808.11 RUS72156.1 - 0.00056 20.0 2.1 0.00086 19.4 0.0 2.0 2 0 0 2 2 2 1 Podoplanin ArgoN PF16486.5 RUS72156.1 - 0.18 12.4 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of argonaute WWamide PF08258.11 RUS72157.1 - 2.8e-07 29.5 103.6 1 9.9 4.2 10.5 10 0 0 10 10 10 8 WWamide peptide RQC PF09382.10 RUS72157.1 - 0.2 11.4 8.4 26 4.6 0.1 4.1 1 1 5 6 6 6 0 RQC domain Adipokin_hormo PF06377.11 RUS72157.1 - 6.1 7.3 24.9 1.3e+02 3.0 0.0 9.4 11 0 0 11 11 11 0 Adipokinetic hormone Uricase PF01014.18 RUS72157.1 - 6.4 7.1 12.9 1.4e+02 2.7 0.2 5.6 1 1 4 5 5 5 0 Uricase Dicty_REP PF05086.12 RUS72159.1 - 0.024 12.6 3.2 0.035 12.1 3.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Innexin PF00876.18 RUS72159.1 - 0.088 12.1 0.9 0.15 11.3 0.9 1.2 1 0 0 1 1 1 0 Innexin FSA_C PF10479.9 RUS72159.1 - 0.12 10.5 7.4 0.15 10.1 7.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LPP20 PF02169.16 RUS72159.1 - 0.13 12.6 2.3 1.7 9.0 3.9 2.0 2 0 0 2 2 2 0 LPP20 lipoprotein SSP160 PF06933.11 RUS72159.1 - 0.18 10.0 20.3 0.35 9.0 20.3 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.11 RUS72159.1 - 4.3 7.2 16.0 9.4 6.1 16.0 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Usp PF00582.26 RUS72160.1 - 2.2e-23 83.3 1.3 4.5e-11 43.4 0.0 2.2 1 1 1 2 2 2 2 Universal stress protein family RAC_head PF16717.5 RUS72161.1 - 2.5e-19 70.0 11.8 2.5e-19 70.0 11.8 4.8 6 1 0 6 6 6 1 Ribosome-associated complex head domain DnaJ PF00226.31 RUS72161.1 - 1.4e-16 60.3 1.4 1.4e-16 60.3 1.4 2.7 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 RUS72161.1 - 1.1e-13 51.2 8.5 1.8e-09 37.6 0.1 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS72161.1 - 9.2e-10 38.6 6.4 2.1e-05 24.7 0.5 4.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain JHD PF17811.1 RUS72162.1 - 1.7e-29 102.4 0.2 1.7e-29 102.4 0.2 3.1 3 0 0 3 3 3 1 Jumonji helical domain JmjC PF02373.22 RUS72162.1 - 2e-09 37.9 0.5 5.7e-08 33.2 0.5 2.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 RUS72162.1 - 2.8e-09 36.7 7.9 7.1e-09 35.4 7.9 1.8 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 RUS72162.1 - 3.3e-08 33.6 0.3 3.3e-08 33.6 0.3 3.3 2 2 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.6 RUS72162.1 - 0.095 12.3 4.1 0.18 11.4 4.1 1.5 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 RUS72162.1 - 2.5 8.3 11.6 0.47 10.6 6.0 2.8 3 0 0 3 3 3 0 PHD-finger Metal_resist PF13801.6 RUS72163.1 - 0.14 12.4 1.2 0.37 11.0 1.2 1.7 1 0 0 1 1 1 0 Heavy-metal resistance GAGA_bind PF06217.12 RUS72165.1 - 5e-05 23.7 12.3 5e-05 23.7 12.3 1.9 2 0 0 2 2 2 1 GAGA binding protein-like family Gly-zipper_Omp PF13488.6 RUS72165.1 - 0.00071 19.5 5.9 0.0015 18.5 5.9 1.5 1 0 0 1 1 1 1 Glycine zipper DDHD PF02862.17 RUS72165.1 - 0.0018 18.5 3.9 0.0025 18.0 3.9 1.3 1 0 0 1 1 1 1 DDHD domain DUF2052 PF09747.9 RUS72165.1 - 0.0057 16.8 7.0 0.0088 16.2 7.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) SRP-alpha_N PF04086.13 RUS72165.1 - 0.0095 15.9 31.0 0.018 15.0 31.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Gly-zipper_YMGG PF13441.6 RUS72165.1 - 0.015 15.0 6.2 0.034 13.9 6.2 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Vfa1 PF08432.10 RUS72165.1 - 0.023 15.0 33.3 0.04 14.3 33.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 UvrD-helicase PF00580.21 RUS72165.1 - 0.035 13.6 10.6 0.046 13.2 10.6 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Dapper PF15268.6 RUS72165.1 - 0.063 12.1 18.8 0.081 11.8 18.8 1.1 1 0 0 1 1 1 0 Dapper DUF4228 PF14009.6 RUS72165.1 - 0.096 13.1 9.0 0.16 12.3 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Zip PF02535.22 RUS72165.1 - 0.12 11.5 8.3 0.18 11.0 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Bacteriocin_IIc PF10439.9 RUS72165.1 - 0.23 11.6 12.0 0.19 11.9 8.0 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Ureide_permease PF07168.11 RUS72165.1 - 0.26 10.0 8.2 0.43 9.3 8.2 1.2 1 0 0 1 1 1 0 Ureide permease DUF3807 PF12720.7 RUS72165.1 - 0.27 11.5 29.5 0.43 10.8 29.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) NARP1 PF12569.8 RUS72165.1 - 0.3 9.9 36.9 0.44 9.4 36.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 RUS72165.1 - 0.31 10.5 17.8 0.44 10.0 17.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_11 PF13086.6 RUS72165.1 - 0.32 10.7 16.3 0.51 10.1 16.3 1.2 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 RUS72165.1 - 0.35 9.8 16.9 0.51 9.3 16.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gly-zipper_OmpA PF13436.6 RUS72165.1 - 0.51 10.2 9.9 0.43 10.4 7.7 2.0 2 1 0 2 2 1 0 Glycine-zipper domain Neur_chan_memb PF02932.16 RUS72165.1 - 0.62 10.1 8.7 0.87 9.6 8.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 RUS72165.1 - 1.2 7.8 20.8 1.9 7.2 20.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rick_17kDa_Anti PF05433.15 RUS72165.1 - 1.3 8.9 8.1 2.7 7.9 8.1 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF2151 PF10221.9 RUS72165.1 - 1.8 7.0 16.0 2.4 6.6 16.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4776 PF16003.5 RUS72165.1 - 1.9 7.4 29.4 2.7 6.9 29.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Membralin PF09746.9 RUS72165.1 - 2.9 6.8 9.2 4.2 6.3 9.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein CDC45 PF02724.14 RUS72165.1 - 3.1 6.0 21.5 4.2 5.5 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RUS72165.1 - 3.4 6.4 26.1 4.8 5.9 26.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RUS72165.1 - 3.6 6.3 15.4 5.1 5.7 15.4 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 RUS72165.1 - 4.3 7.1 27.5 6.8 6.4 27.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 RUS72165.1 - 5.9 6.9 40.4 9.7 6.2 40.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein EOS1 PF12326.8 RUS72165.1 - 6.1 6.7 13.5 11 5.9 13.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 RUS72165.1 - 6.8 6.8 19.3 24 5.1 19.5 1.8 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal RPOL_N PF14700.6 RUS72165.1 - 7.4 5.9 24.6 11 5.2 24.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF5427 PF10310.9 RUS72165.1 - 9.2 5.1 21.4 14 4.5 21.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF913 PF06025.12 RUS72165.1 - 9.6 5.1 9.8 14 4.5 9.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1137 PF06587.11 RUS72166.1 - 1.6e-08 34.6 19.6 0.26 11.3 0.8 5.3 1 1 4 5 5 5 5 Protein of unknown function (DUF1137) TetR_C_9 PF14514.6 RUS72166.1 - 8.2e-05 22.7 0.9 79 3.4 0.0 6.0 1 1 6 7 7 7 0 Tetracyclin repressor-like, C-terminal domain Smoa_sbd PF17885.1 RUS72166.1 - 0.00027 21.0 2.2 97 3.1 0.0 6.1 1 1 8 9 9 9 0 Styrene monooxygenase A putative substrate binding domain TonB_C PF03544.14 RUS72166.1 - 0.022 15.2 15.5 11 6.5 0.2 5.2 2 2 4 7 7 7 0 Gram-negative bacterial TonB protein C-terminal YABBY PF04690.13 RUS72166.1 - 0.071 13.7 38.6 3.6 8.1 4.2 5.7 1 1 5 6 6 6 0 YABBY protein Antifungal_pept PF11410.8 RUS72166.1 - 0.08 12.9 47.5 5.7 6.9 1.0 9.3 1 1 12 13 13 13 0 Antifungal peptide Laminin_EGF PF00053.24 RUS72166.1 - 0.18 12.0 19.9 42 4.4 4.6 5.2 1 1 1 2 2 2 0 Laminin EGF domain DUF727 PF05303.12 RUS72166.1 - 0.36 10.9 6.4 19 5.4 0.1 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF727) Neuralized PF07177.12 RUS72166.1 - 4.3 7.3 12.1 34 4.4 0.4 4.0 1 1 2 3 3 3 0 Neuralized Cu PF17563.2 RUS72167.1 - 8.1e-09 35.5 10.0 20 5.5 0.0 8.3 9 0 0 9 9 9 0 Cupiennin MHC_II_beta PF00969.19 RUS72167.1 - 0.00059 19.9 28.3 5.7 7.1 0.4 7.6 1 1 8 9 9 9 5 Class II histocompatibility antigen, beta domain Amidase02_C PF12123.8 RUS72167.1 - 0.0062 16.2 3.2 8.6 6.1 0.0 4.1 1 1 5 6 6 6 2 N-acetylmuramoyl-l-alanine amidase DUF4119 PF13494.6 RUS72167.1 - 0.0071 16.5 8.3 2.6 8.3 2.0 4.0 1 1 2 3 3 3 2 Domain of unknown function, B. Theta Gene description (DUF4119) HTH_OrfB_IS605 PF12323.8 RUS72167.1 - 0.019 14.5 22.0 6.4 6.3 0.1 6.8 1 1 6 7 7 7 0 Helix-turn-helix domain ETF PF01012.21 RUS72167.1 - 0.042 13.7 0.1 9.9 6.0 0.0 2.6 1 1 1 2 2 2 0 Electron transfer flavoprotein domain YvfG PF09628.10 RUS72167.1 - 0.093 13.1 14.9 46 4.5 0.5 7.1 2 1 6 8 8 8 0 YvfG protein DUF1524 PF07510.11 RUS72167.1 - 0.21 11.5 4.3 6.9 6.5 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1524) RHH_7 PF16777.5 RUS72167.1 - 0.56 10.6 8.3 3.8 8.0 1.6 3.6 1 1 3 4 4 4 0 Transcriptional regulator, RHH-like, CopG A_deaminase_N PF08451.11 RUS72167.1 - 1.8 9.0 5.9 13 6.2 0.3 3.1 1 1 2 3 3 3 0 Adenosine/AMP deaminase N-terminal DUF3566 PF12089.8 RUS72167.1 - 7 7.0 7.4 23 5.3 3.4 2.7 1 1 2 3 3 3 0 Transmembrane domain of unknown function (DUF3566) DAN PF03045.15 RUS72168.1 - 0.0044 17.0 4.1 0.058 13.4 1.3 2.2 1 1 1 2 2 2 2 DAN domain Med15 PF09606.10 RUS72169.1 - 0.46 9.1 25.8 0.66 8.6 25.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 RUS72169.1 - 0.62 9.6 34.2 0.067 12.8 29.5 1.7 2 0 0 2 2 2 0 Spt20 family BUD22 PF09073.10 RUS72169.1 - 0.74 9.1 26.2 1.5 8.1 0.5 2.1 2 0 0 2 2 2 0 BUD22 DUF702 PF05142.12 RUS72169.1 - 0.76 10.2 8.3 1.7 9.1 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) GIDA_assoc PF13932.6 RUS72169.1 - 0.84 9.8 7.1 1.4 9.0 7.1 1.3 1 0 0 1 1 1 0 GidA associated domain eIF-3_zeta PF05091.12 RUS72169.1 - 1 8.2 11.1 1.6 7.6 11.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TraV PF09676.10 RUS72169.1 - 1.2 10.1 11.4 0.29 12.1 7.7 1.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PepSY_TM PF03929.16 RUS72169.1 - 1.5 8.4 4.8 2.2 7.9 4.8 1.2 1 0 0 1 1 1 0 PepSY-associated TM region M_domain PF12938.7 RUS72169.1 - 6.1 6.6 38.1 11 5.7 38.1 1.4 1 0 0 1 1 1 0 M domain of GW182 TERB2 PF15101.6 RUS72169.1 - 7 6.6 15.4 1 9.4 11.2 1.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 RUS72169.1 - 9 5.6 12.5 14 4.9 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ets PF00178.22 RUS72171.1 - 8.6e-35 119.1 0.3 1.4e-34 118.3 0.3 1.4 1 0 0 1 1 1 1 Ets-domain JUPITER PF17054.5 RUS72173.1 - 0.00072 19.1 0.2 0.00072 19.1 0.2 4.0 3 2 1 4 4 4 2 Microtubule-Associated protein Jupiter LRR_6 PF13516.6 RUS72174.1 - 3.9e-14 51.4 7.0 0.0011 18.8 0.0 5.8 5 0 0 5 5 5 4 Leucine Rich repeat EF-hand_1 PF00036.32 RUS72174.1 - 1.5e-10 39.9 4.8 0.00019 20.7 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RUS72174.1 - 1.1e-09 37.5 0.6 0.00061 19.5 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS72174.1 - 1.6e-09 38.1 0.3 1.6e-08 34.8 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS72174.1 - 5.5e-05 22.9 2.6 0.038 13.8 0.0 3.8 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS72174.1 - 0.00049 19.5 4.7 0.011 15.2 0.1 3.3 3 0 0 3 3 3 1 EF hand LRR_1 PF00560.33 RUS72174.1 - 0.0043 17.4 7.3 3 8.8 0.0 4.9 4 1 0 4 4 4 2 Leucine Rich Repeat SPARC_Ca_bdg PF10591.9 RUS72174.1 - 0.015 15.6 0.7 0.051 13.9 0.7 2.0 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_8 PF13855.6 RUS72174.1 - 0.033 13.9 11.2 1.8 8.4 2.2 3.6 2 2 0 2 2 2 0 Leucine rich repeat DUF4734 PF15881.5 RUS72174.1 - 0.078 13.1 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) LRR_4 PF12799.7 RUS72174.1 - 3.2 8.3 14.5 1.4 9.4 0.9 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) RVT_3 PF13456.6 RUS72175.1 - 0.13 12.1 0.9 0.26 11.1 0.9 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF5643 PF18705.1 RUS72175.1 - 1.8 8.6 5.1 9.1 6.3 0.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5643) HECT PF00632.25 RUS72176.1 - 2.4e-89 299.9 0.0 2.7e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glycos_transf_4 PF00953.21 RUS72177.1 - 1.2e-24 87.1 9.1 1.2e-24 87.1 9.1 1.7 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF5058 PF16481.5 RUS72177.1 - 0.0045 16.7 0.2 0.0045 16.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5058) Bactofilin PF04519.13 RUS72178.1 - 9.9e-12 45.0 41.7 0.00045 20.5 12.7 4.4 2 2 1 3 3 3 3 Polymer-forming cytoskeletal Trypan_PARP PF05887.11 RUS72178.1 - 1.6e-07 31.4 106.5 0.16 11.9 18.3 5.1 1 1 4 5 5 5 4 Procyclic acidic repetitive protein (PARP) DUF1943 PF09172.11 RUS72178.1 - 4.1e-07 29.6 0.0 0.43 9.8 0.0 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF1943) MspA PF09203.11 RUS72178.1 - 0.00023 21.1 11.8 0.91 9.4 1.1 3.9 2 2 1 3 3 3 3 MspA DUF481 PF04338.12 RUS72178.1 - 0.003 17.6 6.3 1.9 8.4 0.3 3.3 2 1 1 3 3 3 3 Protein of unknown function, DUF481 DUF1997 PF09366.10 RUS72178.1 - 0.0051 17.0 18.2 0.82 9.8 0.9 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1997) E1_DerP2_DerF2 PF02221.15 RUS72178.1 - 0.052 14.0 15.1 57 4.1 2.0 5.8 1 1 1 2 2 2 0 ML domain BBP2_2 PF10082.9 RUS72178.1 - 0.4 9.4 19.2 1.4 7.7 2.8 3.2 2 1 0 2 2 2 0 Putative beta-barrel porin 2 NESP55 PF06390.12 RUS72178.1 - 0.54 9.8 110.6 24 4.4 17.3 6.1 1 1 2 3 3 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Glyco_hydro_2 PF00703.21 RUS72178.1 - 0.76 10.5 50.7 8.9e+02 0.6 14.5 5.7 2 2 0 2 2 1 0 Glycosyl hydrolases family 2 Exop_C PF18559.1 RUS72178.1 - 4.1 7.3 23.0 23 4.8 4.9 4.0 1 1 0 2 2 2 0 Galactose-binding domain-like Secretin PF00263.21 RUS72178.1 - 5.9 6.5 25.9 0.62 9.7 2.7 3.1 2 1 1 3 3 3 0 Bacterial type II and III secretion system protein DUF2807 PF10988.8 RUS72178.1 - 6.6 6.5 42.5 32 4.2 9.8 5.4 2 2 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Caps_assemb_Wzi PF14052.6 RUS72178.1 - 8.8 5.2 22.2 58 2.6 4.0 4.8 2 2 0 2 2 2 0 Capsule assembly protein Wzi HMMR_N PF15905.5 RUS72179.1 - 0.0021 17.6 1.2 0.0026 17.3 1.2 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF641 PF04859.12 RUS72179.1 - 0.0025 18.1 0.7 0.0029 17.9 0.7 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Spc29 PF17082.5 RUS72179.1 - 0.0048 16.8 0.3 0.0053 16.6 0.3 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF4763 PF15960.5 RUS72179.1 - 0.0054 16.1 2.9 0.0073 15.6 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) TBCA PF02970.16 RUS72179.1 - 0.012 15.9 1.1 0.018 15.4 1.1 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF16 PF01519.16 RUS72179.1 - 0.013 15.9 0.4 0.016 15.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF5382 PF17354.2 RUS72179.1 - 0.019 13.8 0.5 0.025 13.4 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5382) Com_YlbF PF06133.11 RUS72179.1 - 0.036 14.7 4.0 0.045 14.3 4.0 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA TMF_DNA_bd PF12329.8 RUS72179.1 - 0.046 13.7 3.7 0.056 13.4 3.3 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 RUS72179.1 - 0.055 14.1 2.2 0.081 13.5 2.2 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 RUS72179.1 - 0.055 13.7 4.1 0.041 14.1 3.2 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 RUS72179.1 - 0.081 12.7 0.3 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 RUS72179.1 - 0.095 13.3 1.1 0.095 13.3 1.1 1.6 2 0 0 2 2 2 0 SlyX HECT PF00632.25 RUS72180.1 - 1.1e-35 123.7 0.0 1.1e-35 123.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cnn_1N PF07989.11 RUS72181.1 - 0.0061 16.7 2.0 0.0061 16.7 2.0 2.8 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 DUF2433 PF10360.9 RUS72181.1 - 0.02 15.0 0.1 0.075 13.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Mt_ATP-synt_D PF05873.12 RUS72181.1 - 1.1 9.1 7.0 0.31 10.9 0.7 2.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) E2R135 PF11570.8 RUS72181.1 - 1.2 9.4 9.8 0.19 12.0 1.3 3.0 2 1 2 4 4 4 0 Coiled-coil receptor-binding R-domain of colicin E2 zf-MYND PF01753.18 RUS72183.1 - 2.9e-11 43.2 29.8 7.6e-07 29.1 15.8 3.1 2 0 0 2 2 2 2 MYND finger SET PF00856.28 RUS72183.1 - 1e-10 42.2 4.0 5.3e-09 36.7 4.0 2.5 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 RUS72183.1 - 0.0016 18.2 0.3 15 5.6 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 RUS72183.1 - 0.0025 16.9 0.1 0.0038 16.3 0.1 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 RUS72183.1 - 0.02 15.0 0.9 1.3e+02 3.1 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS72183.1 - 0.024 15.4 0.0 11 7.2 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Neur_chan_LBD PF02931.23 RUS72184.1 - 2.7e-44 151.2 0.1 3.4e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS72184.1 - 7.6e-27 94.9 8.2 2.7e-24 86.5 2.0 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tyrosinase PF00264.20 RUS72185.1 - 1.9e-19 70.9 4.1 2.8e-10 40.9 0.2 2.2 1 1 0 2 2 2 2 Common central domain of tyrosinase Sulfotransfer_2 PF03567.14 RUS72186.1 - 1.3e-29 103.9 0.1 1.7e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS72186.1 - 0.022 14.2 0.1 0.052 13.0 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase domain V-SNARE_C PF12352.8 RUS72186.1 - 0.042 14.1 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Stanniocalcin PF03298.13 RUS72187.1 - 7.5e-07 28.7 0.1 9.4e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Stanniocalcin family Kringle PF00051.18 RUS72188.1 - 1e-34 118.7 24.4 1.8e-19 69.8 2.8 3.7 3 0 0 3 3 3 3 Kringle domain Sushi PF00084.20 RUS72188.1 - 4.2e-15 56.1 14.2 1.2e-06 29.0 1.3 4.8 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) fn2 PF00040.19 RUS72188.1 - 0.073 13.4 10.1 0.4 11.0 0.2 3.9 3 0 0 3 3 3 0 Fibronectin type II domain COesterase PF00135.28 RUS72189.1 - 1.1e-139 466.7 0.0 1.4e-139 466.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS72189.1 - 1.2e-05 25.3 1.0 5.1e-05 23.2 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS72189.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 RUS72189.1 - 0.1 12.2 1.6 1.4 8.5 1.6 2.2 1 1 0 1 1 1 0 Putative esterase zf-C3HC4_3 PF13920.6 RUS72190.1 - 9.1e-11 41.5 5.4 1.3e-10 41.0 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS72190.1 - 2.9e-10 40.3 10.2 4e-10 39.9 10.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS72190.1 - 3.8e-10 39.5 8.7 5.2e-10 39.0 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS72190.1 - 1.5e-09 37.7 6.7 9e-09 35.2 7.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS72190.1 - 6.2e-09 35.6 7.1 9.3e-09 35.0 7.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RUS72190.1 - 8.1e-09 35.2 9.5 1.2e-08 34.6 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS72190.1 - 1.3e-07 31.4 7.3 2e-07 30.9 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RUS72190.1 - 1.3e-06 28.5 8.4 1.9e-06 27.9 8.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RUS72190.1 - 1.8e-06 28.1 7.5 3.1e-06 27.4 7.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RUS72190.1 - 5.7e-05 23.1 2.2 8.2e-05 22.6 2.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 RUS72190.1 - 0.00012 22.1 3.0 0.00018 21.4 3.0 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 RUS72190.1 - 0.0021 17.5 0.1 0.0026 17.2 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger IBR PF01485.21 RUS72190.1 - 0.018 15.2 9.4 0.17 12.1 4.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 RUS72190.1 - 0.02 14.7 6.1 0.046 13.5 6.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RUS72190.1 - 0.028 14.0 5.9 0.044 13.4 5.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 RUS72190.1 - 0.038 14.2 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 U-box domain RINGv PF12906.7 RUS72190.1 - 0.091 12.9 7.3 0.28 11.3 7.3 1.8 1 1 0 1 1 1 0 RING-variant domain zf-UDP PF14569.6 RUS72190.1 - 0.15 12.2 1.5 0.31 11.2 1.5 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 RUS72190.1 - 0.58 10.3 5.1 0.91 9.7 5.1 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Pro_isomerase PF00160.21 RUS72191.1 - 4.2e-51 173.3 0.4 1.1e-50 171.9 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 RUS72191.1 - 1.9e-07 30.8 12.1 8.9e-06 25.2 0.3 2.1 2 0 0 2 2 2 2 Rtf2 RING-finger FAR1 PF03101.15 RUS72192.1 - 0.0001 22.9 0.0 0.00028 21.5 0.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF5575 PF17738.1 RUS72192.1 - 0.00013 21.1 0.1 0.00021 20.5 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5575) DUF5095 PF17016.5 RUS72192.1 - 6.1 6.4 8.5 0.1 12.2 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) FAR1 PF03101.15 RUS72193.1 - 5.5e-05 23.8 0.1 0.00016 22.3 0.1 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF5575 PF17738.1 RUS72193.1 - 0.00062 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Exo_endo_phos PF03372.23 RUS72194.1 - 6.7e-10 38.9 0.2 9.7e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spt20 PF12090.8 RUS72195.1 - 2.1 7.9 9.6 2.6 7.6 9.6 1.2 1 0 0 1 1 1 0 Spt20 family FAM216B PF15107.6 RUS72196.1 - 1.2e-05 25.1 0.1 2.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 FAM216B protein family SWIRM-assoc_2 PF16496.5 RUS72196.1 - 1.2 7.9 14.4 2 7.2 14.4 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Cob_adeno_trans PF01923.18 RUS72197.1 - 1.5e-55 187.8 0.0 1.8e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Telethonin PF09470.10 RUS72197.1 - 0.11 12.4 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Telethonin protein SNF5 PF04855.12 RUS72198.1 - 3.7e-57 193.9 0.5 1.4e-31 110.1 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 UPF0300 PF08594.10 RUS72198.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DUF1667 PF07892.11 RUS72198.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) NB-ARC PF00931.22 RUS72199.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF4562 PF15123.6 RUS72200.1 - 0.00023 21.1 6.2 3.1 7.8 0.3 5.1 4 2 1 5 5 5 2 Domain of unknown function (DUF4562) RunxI PF08504.11 RUS72200.1 - 0.13 13.0 6.9 7.5 7.3 0.2 3.9 3 1 0 3 3 3 0 Runx inhibition domain SCA7 PF08313.12 RUS72200.1 - 1.2 9.1 2.8 1.3e+02 2.5 0.1 3.3 3 0 0 3 3 3 0 SCA7, zinc-binding domain Peptidase_S10 PF00450.22 RUS72201.1 - 1.8e-131 439.4 0.1 2.1e-131 439.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4050 PF13259.6 RUS72202.1 - 0.00073 19.9 0.0 13 6.0 0.0 4.5 2 2 2 4 4 4 1 Protein of unknown function (DUF4050) Phasin PF05597.11 RUS72202.1 - 0.051 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zinc_ribbon_10 PF10058.9 RUS72202.1 - 0.063 13.0 6.0 4.4 7.1 0.2 3.5 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein NPR3 PF03666.13 RUS72202.1 - 0.063 12.1 9.1 0.11 11.3 9.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GRAB PF10375.9 RUS72202.1 - 0.1 12.5 15.8 33 4.5 0.2 5.9 6 0 0 6 6 6 0 GRIP-related Arf-binding domain RRM_Rrp7 PF17799.1 RUS72202.1 - 0.16 11.8 2.7 4.3 7.1 0.2 3.5 1 1 2 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF913 PF06025.12 RUS72202.1 - 3 6.7 10.5 1.1 8.1 4.0 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) Drf_FH1 PF06346.12 RUS72203.1 - 0.049 13.4 0.5 0.072 12.8 0.5 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 MPP6 PF10175.9 RUS72204.1 - 1.6e-05 25.4 16.6 0.14 12.6 0.6 3.3 3 0 0 3 3 3 3 M-phase phosphoprotein 6 DUF2052 PF09747.9 RUS72204.1 - 0.00016 21.8 20.9 0.26 11.4 2.2 3.1 3 0 0 3 3 3 3 Coiled-coil domain containing protein (DUF2052) Peptidase_C13 PF01650.18 RUS72204.1 - 0.00033 20.3 0.0 2.7 7.5 0.0 3.3 3 0 0 3 3 3 1 Peptidase C13 family CDC27 PF09507.10 RUS72204.1 - 0.00058 19.4 42.6 0.034 13.5 8.5 3.1 1 1 2 3 3 3 2 DNA polymerase subunit Cdc27 Mpp10 PF04006.12 RUS72204.1 - 0.00074 18.1 47.5 0.045 12.2 10.1 3.0 3 0 0 3 3 3 3 Mpp10 protein RXT2_N PF08595.11 RUS72204.1 - 0.0021 18.1 33.7 0.45 10.5 4.5 3.5 3 0 0 3 3 3 3 RXT2-like, N-terminal CNDH2_C PF16858.5 RUS72204.1 - 0.0024 17.8 22.7 0.26 11.1 3.0 3.1 3 0 0 3 3 3 3 Condensin II complex subunit CAP-H2 or CNDH2, C-term RRM_Rrp7 PF17799.1 RUS72204.1 - 0.0033 17.2 2.7 9.7 6.0 0.1 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Vfa1 PF08432.10 RUS72204.1 - 0.0051 17.2 32.7 0.67 10.3 5.8 3.1 3 0 0 3 3 3 3 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 RUS72204.1 - 0.031 12.5 35.5 0.082 11.1 5.3 3.0 3 0 0 3 3 3 0 Nop14-like family Apo-CII PF05355.11 RUS72204.1 - 0.056 13.6 0.0 56 4.0 0.0 3.3 3 0 0 3 3 3 0 Apolipoprotein C-II FYDLN_acid PF09538.10 RUS72204.1 - 0.099 13.3 47.8 2.2 9.0 11.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) BSP_II PF05432.11 RUS72204.1 - 0.1 12.3 40.3 0.4 10.3 6.0 3.1 2 1 0 3 3 3 0 Bone sialoprotein II (BSP-II) MecA PF05389.12 RUS72204.1 - 0.16 11.6 17.5 2.4 7.7 1.4 3.1 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) DUF4611 PF15387.6 RUS72204.1 - 0.17 12.2 42.3 1.5 9.1 7.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 RUS72204.1 - 0.32 11.4 61.2 2.4 8.6 12.4 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 RUS72204.1 - 0.37 9.9 56.2 1.9 7.6 14.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 RUS72204.1 - 0.38 10.4 29.9 2.2 7.9 3.5 3.4 3 0 0 3 3 3 0 FAM176 family Ferritin-like PF12902.7 RUS72204.1 - 0.41 10.5 9.6 3.7 7.3 1.0 3.2 2 1 1 3 3 3 0 Ferritin-like Pox_Ag35 PF03286.14 RUS72204.1 - 0.43 10.3 36.0 2.3 8.0 5.5 3.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein CLPTM1 PF05602.12 RUS72204.1 - 0.75 8.7 14.3 1.9 7.4 1.1 3.1 3 0 0 3 3 3 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) PTPRCAP PF15713.5 RUS72204.1 - 1 9.7 27.2 4.2 7.6 1.9 3.3 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated eIF-3c_N PF05470.12 RUS72204.1 - 1.2 7.4 34.1 1 7.6 5.6 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 RUS72204.1 - 1.2 7.1 51.7 0.57 8.2 12.4 3.1 3 0 0 3 3 3 0 DNA polymerase phi Mak16 PF04874.14 RUS72204.1 - 1.7 9.3 29.8 4.2 8.0 2.7 3.2 3 0 0 3 3 3 0 Mak16 protein C-terminal region Sec62 PF03839.16 RUS72204.1 - 2.5 7.6 12.8 13 5.2 0.5 3.1 3 0 0 3 3 3 0 Translocation protein Sec62 Med8 PF10232.9 RUS72204.1 - 3.1 7.3 13.9 6.9 6.2 0.4 3.1 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 SDA1 PF05285.12 RUS72204.1 - 3.2 7.1 41.6 0.7 9.3 6.8 3.1 3 0 0 3 3 3 0 SDA1 XAP5 PF04921.14 RUS72204.1 - 3.7 7.3 29.3 3.8 7.3 4.3 3.1 3 0 0 3 3 3 0 XAP5, circadian clock regulator Cwf_Cwc_15 PF04889.12 RUS72204.1 - 6.4 6.4 53.0 4.3 7.0 13.2 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF5538 PF17692.1 RUS72204.1 - 6.7 6.8 29.3 5.7 7.0 1.9 5.3 4 1 2 6 6 6 0 Family of unknown function (DUF5538) ORC3_N PF07034.11 RUS72204.1 - 6.7 5.7 5.6 25 3.8 0.0 2.9 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 3 N-terminus I_LWEQ PF01608.17 RUS72204.1 - 6.9 6.9 23.5 5.6 7.2 3.5 3.2 3 0 0 3 3 3 0 I/LWEQ domain Nucleo_P87 PF07267.11 RUS72204.1 - 9.6 4.9 35.6 0.71 8.7 6.0 3.0 1 1 1 3 3 3 0 Nucleopolyhedrovirus capsid protein P87 7TM_GPCR_Srx PF10328.9 RUS72205.1 - 7.5e-07 29.0 17.3 9.1e-07 28.8 17.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS72205.1 - 2.4e-05 23.8 11.2 3.1e-05 23.5 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS72206.1 - 1.3e-11 44.4 24.8 2.1e-11 43.6 24.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72206.1 - 1.5e-07 31.3 25.9 1.5e-07 31.3 25.9 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS72206.1 - 0.012 15.0 27.9 0.014 14.7 26.0 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 RUS72206.1 - 0.13 11.6 30.8 0.24 10.8 30.8 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx TolA_bind_tri PF16331.5 RUS72207.1 - 0.0027 17.7 0.3 0.0027 17.7 0.3 2.2 2 1 0 2 2 2 1 TolA binding protein trimerisation Tektin PF03148.14 RUS72207.1 - 0.0058 15.4 2.0 0.0089 14.8 1.4 1.5 1 1 0 1 1 1 1 Tektin family DUF4988 PF16378.5 RUS72207.1 - 0.016 14.9 2.2 0.47 10.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function CHGN PF05679.16 RUS72207.1 - 0.019 13.8 0.2 0.025 13.4 0.2 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase HMMR_N PF15905.5 RUS72207.1 - 0.021 14.3 4.3 0.03 13.8 4.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 RUS72207.1 - 0.025 14.6 4.0 0.044 13.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 RUS72207.1 - 0.029 13.4 2.6 0.039 12.9 2.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 RUS72207.1 - 0.048 14.1 5.1 3 8.3 0.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 RUS72207.1 - 0.063 13.6 2.1 1.6 9.1 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.12 RUS72207.1 - 0.063 13.3 4.3 0.55 10.2 4.2 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF724 PF05266.14 RUS72207.1 - 0.078 12.8 4.8 0.13 12.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Snapin_Pallidin PF14712.6 RUS72207.1 - 0.1 13.1 3.3 0.23 11.9 3.3 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DUF16 PF01519.16 RUS72207.1 - 0.32 11.5 6.2 0.54 10.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.11 RUS72207.1 - 0.37 9.6 4.7 0.54 9.1 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 RUS72207.1 - 0.38 11.2 5.9 7.9 7.0 0.8 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SWI-SNF_Ssr4 PF08549.10 RUS72207.1 - 0.5 8.9 3.1 0.66 8.5 3.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DivIC PF04977.15 RUS72207.1 - 0.75 9.6 6.2 1.6 8.6 1.2 2.3 1 1 1 2 2 2 0 Septum formation initiator BST2 PF16716.5 RUS72207.1 - 2.1 9.0 5.2 1.3 9.6 2.6 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 7tm_1 PF00001.21 RUS72209.1 - 1.7e-11 44.0 20.8 2.5e-11 43.4 20.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72209.1 - 2.5e-09 37.2 17.1 2.5e-09 37.2 17.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS72209.1 - 1.9e-08 34.0 9.7 1.9e-08 34.0 9.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 RUS72209.1 - 0.13 11.9 31.5 0.49 10.0 30.9 2.1 1 1 1 2 2 2 0 Srg family chemoreceptor Ribosomal_L20 PF00453.18 RUS72210.1 - 6.5e-24 84.1 1.2 8.7e-24 83.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L20 Lectin_C PF00059.21 RUS72211.1 - 4.7e-15 56.2 2.2 1.1e-14 55.1 2.2 1.7 1 0 0 1 1 1 1 Lectin C-type domain TMEM154 PF15102.6 RUS72211.1 - 0.074 12.9 4.7 2.3 8.1 6.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family Rubella_E2 PF05749.11 RUS72211.1 - 0.53 9.7 6.3 0.97 8.8 6.3 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Gram_pos_anchor PF00746.21 RUS72211.1 - 1.3 9.0 4.6 3.7 7.6 4.6 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif SSP160 PF06933.11 RUS72211.1 - 2.9 6.0 15.0 5.8 5.0 15.0 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Guanylate_cyc PF00211.20 RUS72212.1 - 6e-51 172.7 0.4 9e-51 172.1 0.4 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 RUS72212.1 - 1.1e-23 83.9 0.0 2.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 RUS72212.1 - 1.9e-16 60.2 0.1 4.2e-16 59.1 0.1 1.5 2 0 0 2 2 2 1 Heme NO binding associated Cuticle_2 PF08184.11 RUS72215.1 - 1.1e-06 28.5 11.6 73 3.5 0.0 12.1 15 0 0 15 15 15 0 Cuticle protein 7 isoform family Sec_GG PF07549.14 RUS72215.1 - 0.078 12.5 30.6 1.1e+02 2.5 0.1 11.8 12 0 0 12 12 12 0 SecD/SecF GG Motif GreA_GreB PF01272.19 RUS72215.1 - 0.094 12.6 13.7 2.8e+02 1.5 0.0 11.2 16 0 0 16 16 16 0 Transcription elongation factor, GreA/GreB, C-term Ank_2 PF12796.7 RUS72217.1 - 1.4e-16 60.8 0.0 1.6e-09 38.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72217.1 - 6.4e-12 45.8 0.2 3.4e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS72217.1 - 2.9e-11 43.4 0.5 6.5e-05 23.1 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72217.1 - 4.1e-08 32.9 0.1 0.0064 16.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat SAM_1 PF00536.30 RUS72217.1 - 1.8e-06 28.3 0.0 5.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 RUS72217.1 - 2.2e-06 27.8 0.1 0.02 15.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat SAM_2 PF07647.17 RUS72217.1 - 0.00054 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FliJ PF02050.16 RUS72217.1 - 0.6 10.3 9.5 0.42 10.8 6.8 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-B_dimeris PF09026.10 RUS72217.1 - 5.9 7.4 10.4 12 6.4 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SERTA PF06031.13 RUS72218.1 - 3.9e-06 26.4 16.3 20 4.9 0.0 8.6 3 3 10 13 13 13 8 SERTA motif Mucin-like PF16058.5 RUS72218.1 - 0.00076 19.5 39.3 0.04 14.0 19.0 2.8 1 1 1 3 3 3 3 Mucin-like Extensin_2 PF04554.13 RUS72218.1 - 0.0017 18.4 53.7 0.021 14.9 18.5 3.7 2 1 0 2 2 2 2 Extensin-like region GatB_N PF02934.15 RUS72218.1 - 2 7.8 15.0 21 4.4 0.2 5.0 2 2 1 3 3 3 0 GatB/GatE catalytic domain Jiraiya PF15038.6 RUS72219.1 - 0.71 9.3 38.0 18 4.7 0.8 8.2 1 1 7 8 8 8 0 Jiraiya Oxidored_q2 PF00420.24 RUS72220.1 - 0.076 12.7 0.2 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Miga PF10265.9 RUS72220.1 - 4.6 6.1 7.3 8.3 5.3 7.3 1.3 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 RUS72220.1 - 8.2 5.2 10.2 17 4.1 10.2 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain EGL-1 PF11430.8 RUS72221.1 - 1.6 8.7 6.4 1.4e+02 2.5 0.0 6.0 10 0 0 10 10 10 0 Programmed cell death activator EGL-1 TPT PF03151.16 RUS72223.1 - 1.6e-07 31.0 1.4 1.8e-07 30.9 1.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family ANF_receptor PF01094.28 RUS72224.1 - 2.4e-101 339.4 0.0 3.6e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 RUS72224.1 - 3.7e-65 220.0 24.1 6.9e-65 219.1 24.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 RUS72224.1 - 6.4e-13 48.5 15.4 6.4e-13 48.5 15.4 1.9 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 RUS72224.1 - 6.2e-11 42.5 0.0 1.8e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein Fz PF01392.22 RUS72225.1 - 7.2e-54 181.1 13.7 3.5e-27 95.2 2.1 2.0 2 0 0 2 2 2 2 Fz domain Glypican PF01153.19 RUS72225.1 - 0.014 14.2 3.3 0.9 8.3 0.4 2.1 2 0 0 2 2 2 0 Glypican Mid1 PF12929.7 RUS72225.1 - 0.037 13.2 11.2 2.9 7.0 0.2 3.9 2 2 2 4 4 4 0 Stretch-activated Ca2+-permeable channel component Meiotic_rec114 PF03525.14 RUS72225.1 - 0.064 12.2 0.1 7.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Meiotic recombination protein rec114 Vitelline_membr PF10542.9 RUS72225.1 - 3.9 7.4 10.2 4.6 7.2 1.5 2.7 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Fz PF01392.22 RUS72226.1 - 5.8e-25 88.1 0.9 9.3e-25 87.4 0.9 1.3 1 0 0 1 1 1 1 Fz domain Glypican PF01153.19 RUS72226.1 - 0.28 10.0 2.0 0.24 10.2 0.6 1.6 1 1 1 2 2 2 0 Glypican Glycos_transf_2 PF00535.26 RUS72227.1 - 1.2e-25 90.3 0.0 2.4e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS72227.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS72227.1 - 0.00016 21.3 0.0 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Med20 PF08612.11 RUS72227.1 - 0.14 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF4390 PF14334.6 RUS72228.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) MFS_1 PF07690.16 RUS72230.1 - 8.5e-26 90.7 35.7 1.9e-14 53.4 17.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily FAM110_N PF14161.6 RUS72231.1 - 6 7.1 14.2 4.5 7.5 0.6 3.6 2 2 1 3 3 3 0 Centrosome-associated N terminus SNAPc_SNAP43 PF09808.9 RUS72232.1 - 2.3e-51 174.4 5.4 4.9e-51 173.4 5.4 1.6 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 BTB PF00651.31 RUS72233.1 - 5.7e-31 107.0 2.7 9.6e-31 106.3 2.7 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 RUS72233.1 - 1.2e-30 104.9 6.8 2.3e-08 33.5 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RUS72233.1 - 1.2e-27 95.2 8.9 4.9e-08 33.0 0.2 6.3 2 1 4 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RUS72233.1 - 3.8e-15 55.7 0.7 0.00015 22.0 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS72233.1 - 1e-12 47.8 8.5 0.0042 17.1 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS72233.1 - 6.5e-12 44.9 12.3 0.0016 18.3 0.1 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 RUS72233.1 - 5.3e-08 32.7 9.1 0.038 14.0 0.2 5.6 5 0 0 5 5 5 2 Kelch motif DUF3342 PF11822.8 RUS72233.1 - 0.00028 21.0 0.4 0.00064 19.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 RUS72233.1 - 0.0043 17.2 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain WD40 PF00400.32 RUS72234.1 - 1.5e-07 32.0 3.6 0.65 11.0 0.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 RUS72234.1 - 0.00084 19.3 0.1 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RUS72234.1 - 0.00091 19.5 0.0 0.69 10.3 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS72234.1 - 0.0051 16.2 0.1 0.27 10.5 0.0 2.6 2 1 0 2 2 2 1 WD40-like domain CTP_transf_like PF01467.26 RUS72235.1 - 3.4e-06 27.3 0.0 5.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DNA_pol_A PF00476.20 RUS72236.1 - 1.6e-114 382.9 0.4 2e-114 382.6 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 RUS72236.1 - 2e-06 27.4 2.1 0.00039 19.9 0.3 2.5 1 1 1 2 2 2 2 DNA polymerase nu pseudo-exo Jnk-SapK_ap_N PF09744.9 RUS72238.1 - 0.85 9.8 6.4 0.35 11.1 3.2 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-C3HC4_3 PF13920.6 RUS72239.1 - 4.5e-09 36.0 6.9 8.2e-09 35.2 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 RUS72239.1 - 5.5e-09 35.7 2.7 5.5e-09 35.7 2.7 1.8 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 RUS72239.1 - 2.5e-08 33.6 10.7 5e-08 32.7 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS72239.1 - 1.4e-06 28.1 11.5 2.9e-06 27.0 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS72239.1 - 8.7e-06 25.6 12.2 1.6e-05 24.8 12.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS72239.1 - 9.1e-06 25.9 9.7 1.8e-05 24.9 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 RUS72239.1 - 5.9e-05 23.0 4.4 5.9e-05 23.0 4.4 2.1 2 0 0 2 2 1 1 Zinc finger domain zf-RING_UBOX PF13445.6 RUS72239.1 - 7.6e-05 22.6 10.7 0.00018 21.5 10.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 RUS72239.1 - 0.00041 20.1 2.7 0.00041 20.1 2.7 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 RUS72239.1 - 0.00091 19.3 8.8 0.00091 19.3 8.8 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS72239.1 - 0.0034 17.2 8.0 0.0069 16.2 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 RUS72239.1 - 0.0071 16.1 4.6 0.014 15.2 4.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 RUS72239.1 - 0.0071 16.0 4.6 0.013 15.2 4.6 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_10 PF16685.5 RUS72239.1 - 0.031 14.4 6.8 0.031 14.4 6.8 2.0 3 0 0 3 3 1 0 zinc RING finger of MSL2 FYVE_2 PF02318.16 RUS72239.1 - 0.19 12.0 5.0 1 9.6 3.3 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_6 PF14835.6 RUS72239.1 - 1.3 9.0 4.2 2.5 8.0 4.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_2 PF14608.6 RUS72239.1 - 1.3 9.6 7.6 0.11 13.0 2.5 2.0 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 RUS72239.1 - 5 7.5 9.7 88 3.5 9.7 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain SOG2 PF10428.9 RUS72241.1 - 2 7.5 14.9 2.4 7.3 14.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CC2D2AN-C2 PF15625.6 RUS72243.1 - 3.9e-54 183.0 0.0 1.3e-53 181.3 0.0 2.0 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF5523 PF17661.1 RUS72243.1 - 5.8e-42 144.1 24.9 5.8e-42 144.1 24.9 4.0 3 1 0 3 3 3 1 Family of unknown function (DUF5523) C2 PF00168.30 RUS72243.1 - 0.00023 21.4 0.3 0.59 10.5 0.0 3.3 3 1 0 3 3 3 2 C2 domain PAC3 PF10178.9 RUS72244.1 - 4e-18 65.3 0.4 4.9e-18 65.1 0.4 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Tmemb_14 PF03647.13 RUS72245.1 - 1.1e-30 106.2 10.3 1.2e-30 106.0 10.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Ribosomal_L27A PF00828.19 RUS72246.1 - 1.6e-22 80.6 0.0 2.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DENN PF02141.21 RUS72247.1 - 2.6e-49 167.7 1.4 4.7e-49 166.9 1.4 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RUS72247.1 - 9.3e-12 45.5 0.1 9.3e-12 45.5 0.1 3.1 3 0 0 3 3 3 1 uDENN domain dDENN PF03455.19 RUS72247.1 - 1.6e-08 34.4 1.7 3.6e-08 33.3 0.9 2.1 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 RUS72247.1 - 5.3e-05 23.1 0.3 0.0001 22.2 0.3 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis LcrV PF04792.12 RUS72247.1 - 0.077 12.3 0.9 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 V antigen (LcrV) protein ASC PF00858.24 RUS72250.1 - 3e-67 227.5 7.8 4.1e-36 124.9 7.5 2.1 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel FR47 PF08445.10 RUS72251.1 - 3.2e-11 43.0 0.0 9.9e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 RUS72251.1 - 5.9e-06 26.5 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Gly_acyl_tr_N PF06021.11 RUS72251.1 - 5e-05 23.5 0.0 0.0015 18.6 0.0 2.3 1 1 1 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_10 PF13673.7 RUS72251.1 - 0.00031 20.7 0.0 0.00072 19.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS72251.1 - 0.0018 18.6 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RUS72251.1 - 0.0025 18.5 0.0 0.0047 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH3_9 PF14604.6 RUS72253.1 - 0.00024 20.9 0.0 0.0006 19.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain NodZ PF05830.11 RUS72253.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Ntox37 PF15535.6 RUS72253.1 - 0.17 12.3 0.1 0.29 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 37 SH3_2 PF07653.17 RUS72254.1 - 2.6e-11 43.0 0.0 6.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS72254.1 - 4.9e-11 42.0 0.6 2.1e-10 40.0 0.6 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS72254.1 - 5.9e-09 35.7 0.3 2.1e-08 33.9 0.3 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 RUS72254.1 - 0.075 13.3 1.2 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain ThiF PF00899.21 RUS72255.1 - 4.3e-31 108.1 0.0 6.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RUS72255.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1241 PF06840.11 RUS72256.1 - 7.1e-50 168.6 0.2 9.5e-50 168.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Med11 PF10280.9 RUS72256.1 - 0.0036 17.8 0.2 0.0071 16.8 0.2 1.4 1 0 0 1 1 1 1 Mediator complex protein APG17 PF04108.12 RUS72256.1 - 0.017 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Focal_AT PF03623.13 RUS72256.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Focal adhesion targeting region RBP_receptor PF14752.6 RUS72258.1 - 2.8e-25 89.0 5.1 3.3e-25 88.8 5.1 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor NADH_u_ox_C PF12853.7 RUS72259.1 - 0.041 13.8 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit IRF PF00605.17 RUS72260.1 - 6.3e-24 84.3 2.2 1.5e-23 83.1 2.2 1.7 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 RUS72260.1 - 8.1e-15 55.1 0.3 2.6e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Interferon-regulatory factor 3 CDC73_C PF05179.14 RUS72262.1 - 3.7e-44 150.2 1.3 4.1e-44 150.0 1.3 1.0 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal ANF_receptor PF01094.28 RUS72264.1 - 6e-59 199.9 0.1 8.2e-59 199.5 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS72264.1 - 1.8e-35 122.5 0.0 2.8e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS72264.1 - 7.2e-27 94.4 0.0 1.5e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 RUS72264.1 - 1.1e-17 64.3 0.9 1.3e-13 51.0 0.1 3.2 2 1 1 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 RUS72264.1 - 0.00055 19.7 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein HNOBA PF07701.14 RUS72264.1 - 0.00084 18.8 1.1 0.0016 17.9 1.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated DUF4264 PF14084.6 RUS72264.1 - 0.08 12.6 1.2 0.59 9.8 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4264) DUF3958 PF13125.6 RUS72264.1 - 0.74 10.0 3.3 19 5.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) ClpS PF02617.17 RUS72264.1 - 3.2 7.6 5.4 28 4.6 1.1 2.7 1 1 1 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS SSF PF00474.17 RUS72266.1 - 2.6e-39 135.3 23.9 3.4e-39 134.9 23.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF485 PF04341.12 RUS72266.1 - 0.0028 17.6 0.2 0.0028 17.6 0.2 3.7 4 1 1 5 5 5 1 Protein of unknown function, DUF485 Mito_carr PF00153.27 RUS72268.1 - 3e-70 232.2 0.8 1.6e-25 88.8 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 RUS72268.1 - 7.1e-19 65.9 0.8 4.8e-06 25.7 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS72268.1 - 2.1e-16 60.1 5.6 8.5e-07 29.3 0.4 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS72268.1 - 5.9e-15 53.9 1.5 2.2e-05 24.0 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RUS72268.1 - 6.5e-11 41.2 1.3 0.0064 15.9 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS72268.1 - 3.5e-08 33.2 1.1 0.022 14.6 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 RUS72268.1 - 2.3 8.1 5.2 18 5.3 0.2 3.0 3 0 0 3 3 3 0 EF hand Lectin_C PF00059.21 RUS72269.1 - 5.6e-06 27.0 0.2 5.6e-06 27.0 0.2 1.8 2 1 0 2 2 2 1 Lectin C-type domain VSP PF03302.13 RUS72269.1 - 0.00043 19.2 0.3 0.00075 18.5 0.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD99L2 PF12301.8 RUS72269.1 - 0.027 14.8 1.4 0.027 14.8 1.4 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 PARM PF17061.5 RUS72269.1 - 0.43 10.7 2.2 0.84 9.7 2.2 1.4 1 0 0 1 1 1 0 PARM DUF2613 PF11021.8 RUS72269.1 - 3.7 7.7 8.6 13 5.9 8.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Lectin_C PF00059.21 RUS72270.1 - 6.6e-147 480.4 58.1 8.8e-22 77.9 6.8 9.2 9 0 0 9 9 9 9 Lectin C-type domain UL45 PF05473.12 RUS72270.1 - 4.6e-08 32.9 31.2 0.28 10.8 0.0 9.6 6 3 3 9 9 9 5 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 RUS72270.1 - 6.8e-06 25.5 8.4 0.41 9.9 0.0 5.3 6 0 0 6 6 6 3 Chordopoxvirus A33R protein Xlink PF00193.17 RUS72270.1 - 2.3e-05 24.7 18.7 1.3 9.4 0.1 8.8 8 2 2 10 10 10 3 Extracellular link domain DUF1648 PF07853.11 RUS72270.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Presenilin PF01080.17 RUS72271.1 - 0.4 9.4 16.1 0.39 9.4 16.1 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 RUS72271.1 - 0.57 8.9 19.7 0.66 8.7 19.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 RUS72271.1 - 2.6 7.9 42.9 3.2 7.6 42.9 1.2 1 0 0 1 1 1 0 SPX domain CSG2 PF16965.5 RUS72271.1 - 3.2 6.6 10.9 4 6.3 10.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DAO PF01266.24 RUS72272.1 - 1.3e-66 225.6 0.0 1.8e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 RUS72272.1 - 0.00042 19.0 0.1 0.0096 14.5 0.1 2.3 2 1 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 RUS72272.1 - 0.0016 18.6 0.1 0.0087 16.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS72272.1 - 0.008 15.5 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GMC_oxred_N PF00732.19 RUS72272.1 - 0.031 13.7 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 RUS72272.1 - 0.052 13.5 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 RUS72272.1 - 0.088 12.0 0.1 0.23 10.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RUS72272.1 - 0.097 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 RUS72272.1 - 0.11 11.7 0.1 4.7 6.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain UPF0020 PF01170.18 RUS72273.1 - 1.6e-17 63.8 0.0 6.2e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 RUS72273.1 - 8.3e-12 45.1 0.6 1.9e-11 44.0 0.2 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS72273.1 - 3.4e-09 37.3 0.0 1.2e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS72273.1 - 4.7e-08 33.6 0.0 2.3e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS72273.1 - 9.1e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 RUS72273.1 - 0.0027 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase THUMP PF02926.17 RUS72273.1 - 0.0069 16.5 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 THUMP domain LRR_8 PF13855.6 RUS72274.1 - 0.0018 18.0 4.4 0.22 11.3 0.1 3.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 RUS72274.1 - 0.0086 16.5 4.1 0.94 10.0 0.0 4.4 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS72274.1 - 0.14 12.3 4.9 10 6.5 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat tRNA-synt_1b PF00579.25 RUS72275.1 - 4.5e-21 75.4 0.0 7.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WD40 PF00400.32 RUS72277.1 - 1.6e-13 50.8 9.3 0.093 13.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72277.1 - 2.4e-06 27.8 0.0 0.059 13.7 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RUS72277.1 - 0.11 12.0 0.1 6.1 6.4 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.16 RUS72277.1 - 0.16 10.5 0.1 0.58 8.6 0.0 1.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 RUS72278.1 - 2.1e-55 183.4 24.9 4.5e-11 43.1 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 RUS72278.1 - 9.9e-36 122.8 3.4 2.1e-35 121.8 3.4 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 RUS72278.1 - 5e-15 55.6 0.0 3.8e-05 23.9 0.0 5.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS72278.1 - 1.1e-07 30.9 2.0 0.013 14.2 0.0 4.5 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS72278.1 - 1e-06 28.0 0.1 0.29 10.0 0.0 4.6 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RUS72278.1 - 0.0026 17.2 0.0 28 3.9 0.0 4.2 4 1 0 5 5 5 0 WD40-like domain eIF2A PF08662.11 RUS72278.1 - 0.0034 17.3 0.0 0.34 10.8 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 RUS72278.1 - 0.011 14.1 0.0 0.024 13.0 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 RUS72278.1 - 0.021 13.4 0.3 0.6 8.6 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain Fascin PF06268.13 RUS72279.1 - 6.1e-72 238.9 2.5 2.4e-28 98.5 1.1 4.1 4 0 0 4 4 4 4 Fascin domain FRG1 PF06229.12 RUS72279.1 - 7e-15 55.2 2.0 4.4e-06 26.5 0.2 5.3 1 1 4 6 6 6 3 FRG1-like domain DUF569 PF04601.13 RUS72279.1 - 0.0004 20.1 0.7 2.5 7.8 0.1 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF569) Hyd_WA PF06462.12 RUS72281.1 - 3.4e-41 138.9 45.3 1.6e-09 37.6 1.1 8.8 8 0 0 8 8 8 6 Propeller Pex24p PF06398.11 RUS72281.1 - 3.8e-16 59.0 26.5 3.4e-09 36.2 9.6 2.4 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PH PF00169.29 RUS72281.1 - 0.013 16.0 0.0 0.051 14.1 0.0 2.1 1 0 0 1 1 1 0 PH domain Galactosyl_T PF01762.21 RUS72282.1 - 5.2e-36 124.3 0.0 2.9e-35 121.9 0.0 2.2 2 1 0 2 2 2 1 Galactosyltransferase Asparaginase_2 PF01112.18 RUS72283.1 - 1.1e-77 261.1 2.5 1.4e-77 260.8 2.5 1.1 1 0 0 1 1 1 1 Asparaginase C_GCAxxG_C_C PF09719.10 RUS72284.1 - 0.12 12.7 0.3 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Ank_2 PF12796.7 RUS72286.1 - 1.2e-69 230.9 15.5 4.6e-12 46.4 0.0 10.4 4 3 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72286.1 - 9.6e-54 179.1 22.6 5.5e-05 23.6 0.0 15.2 6 3 9 16 16 16 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS72286.1 - 2.2e-48 161.7 22.4 4.7e-07 30.0 0.0 14.0 10 3 4 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72286.1 - 7.4e-44 142.7 17.0 0.0023 18.3 0.0 18.4 19 0 0 19 19 19 12 Ankyrin repeat Ank PF00023.30 RUS72286.1 - 3.6e-36 122.0 19.2 0.006 17.0 0.0 16.9 17 1 0 17 17 17 11 Ankyrin repeat C2-set_2 PF08205.12 RUS72287.1 - 0.00036 20.5 0.7 1.2 9.2 0.0 2.9 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 RUS72287.1 - 0.00069 19.9 0.9 0.018 15.4 0.1 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 RUS72287.1 - 0.0027 18.3 2.2 0.24 12.0 0.1 2.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS72287.1 - 0.057 13.6 3.1 0.28 11.4 0.9 2.7 2 1 0 2 2 2 0 Immunoglobulin domain Il2rg PF15874.5 RUS72288.1 - 5.6e-20 71.4 0.0 7.7e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain p450 PF00067.22 RUS72289.1 - 3e-35 121.9 0.0 3.5e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PDZ PF00595.24 RUS72290.1 - 2e-65 217.1 23.4 8.2e-15 54.9 0.8 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 RUS72290.1 - 1.7e-37 127.0 24.2 6.3e-09 35.5 1.8 5.7 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 RUS72290.1 - 2.5e-13 50.1 11.2 0.043 14.1 0.2 5.6 5 0 0 5 5 5 5 PDZ domain L27_2 PF09045.10 RUS72290.1 - 5.2e-08 32.7 0.5 1.7e-07 31.1 0.5 1.9 1 0 0 1 1 1 1 L27_2 L27_1 PF09058.10 RUS72290.1 - 0.017 15.1 0.4 0.057 13.4 0.4 2.0 1 0 0 1 1 1 0 L27_1 GDWWSH PF15667.5 RUS72291.1 - 9.4e-21 74.4 0.5 9.4e-21 74.4 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function with motif GDWWSH Ank_2 PF12796.7 RUS72292.1 - 8.4e-42 141.6 6.7 4.4e-18 65.6 0.8 5.7 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS72292.1 - 9.3e-33 108.6 10.2 0.00038 20.7 0.0 10.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 RUS72292.1 - 2.9e-31 107.1 10.9 6.2e-08 32.8 0.1 8.7 4 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS72292.1 - 3.9e-30 103.8 8.8 6.7e-07 29.7 0.1 6.8 5 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS72292.1 - 3.3e-24 84.2 12.9 0.00021 21.6 0.1 9.1 9 1 0 9 9 9 6 Ankyrin repeat SOCS_box PF07525.16 RUS72292.1 - 1.6e-06 28.4 0.2 3.6e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 SOCS box DXPR_C PF13288.6 RUS72292.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain SKIP_SNW PF02731.15 RUS72293.1 - 4.1e-71 237.8 4.5 4.1e-71 237.8 4.5 2.1 3 0 0 3 3 3 1 SKIP/SNW domain Menin PF05053.13 RUS72294.1 - 1.2e-23 83.5 0.1 1.5e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Menin Menin PF05053.13 RUS72295.1 - 4e-161 537.7 3.4 8.3e-146 487.1 0.1 2.2 1 1 1 2 2 2 2 Menin RVT_1 PF00078.27 RUS72295.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.17 RUS72295.1 - 0.035 14.2 0.4 0.13 12.5 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SERTA PF06031.13 RUS72296.1 - 0.00038 20.1 1.9 0.0012 18.5 1.9 1.9 1 1 0 1 1 1 1 SERTA motif DUF2802 PF10975.8 RUS72296.1 - 0.018 15.1 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Sulfotransfer_1 PF00685.27 RUS72297.1 - 7.8e-37 127.2 0.5 2.8e-36 125.4 0.5 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS72297.1 - 7.4e-07 29.8 0.0 1.4e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family RVT_1 PF00078.27 RUS72298.1 - 0.095 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CD52 PF15116.6 RUS72298.1 - 0.22 11.5 0.4 32 4.7 0.0 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen M PF02370.16 RUS72298.1 - 0.56 10.9 3.0 1.9 9.3 0.2 2.7 2 0 0 2 2 2 0 M protein repeat Acyltransferase PF01553.21 RUS72299.1 - 5e-18 65.0 0.0 7.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RUS72299.1 - 2e-16 59.8 0.3 4e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Exo_endo_phos PF03372.23 RUS72300.1 - 1.9e-08 34.1 0.0 2.8e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_1 PF00001.21 RUS72302.1 - 2.9e-48 164.5 1.1 3.5e-48 164.2 1.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS72302.1 - 1.2e-07 31.8 12.5 1.9e-07 31.1 6.3 2.6 2 1 1 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS72302.1 - 0.0012 18.5 10.3 0.002 17.8 10.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SDA1 PF05285.12 RUS72303.1 - 0.00044 19.8 12.3 0.00053 19.5 12.3 1.1 1 0 0 1 1 1 1 SDA1 PTPRCAP PF15713.5 RUS72303.1 - 5.6 7.2 11.6 3.8 7.8 6.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PRKCSH-like PF12999.7 RUS72304.1 - 1.6e-40 138.8 8.4 1.6e-40 138.8 8.4 2.5 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RUS72304.1 - 7e-25 87.5 0.1 1.7e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RUS72304.1 - 1.9e-08 35.2 3.9 1.9e-08 35.2 3.9 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein EF-hand_1 PF00036.32 RUS72304.1 - 4.1e-07 29.1 0.9 0.019 14.5 0.0 3.1 1 1 1 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS72304.1 - 4.5e-05 23.1 0.4 0.061 13.3 0.0 3.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS72304.1 - 0.00047 19.5 5.6 0.042 13.3 0.0 3.3 2 1 1 3 3 3 2 EF hand Ldl_recept_a PF00057.18 RUS72304.1 - 0.0059 16.8 4.0 0.0059 16.8 4.0 3.6 3 1 1 4 4 4 2 Low-density lipoprotein receptor domain class A EF-hand_7 PF13499.6 RUS72304.1 - 0.77 10.3 10.0 0.41 11.1 0.4 3.2 2 1 1 3 3 3 0 EF-hand domain pair DNA_pol_phi PF04931.13 RUS72305.1 - 2e-05 22.9 39.2 2.7e-05 22.5 39.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RUS72305.1 - 0.00054 18.3 25.7 0.00063 18.1 25.7 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS72305.1 - 0.014 14.9 30.6 0.017 14.6 30.6 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 RUS72305.1 - 0.023 13.5 4.3 0.024 13.5 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 RUS72305.1 - 0.032 12.7 22.1 0.039 12.4 22.1 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 RUS72305.1 - 0.21 10.6 0.7 0.23 10.4 0.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NAM-associated PF14303.6 RUS72305.1 - 0.26 12.0 5.2 0.38 11.5 5.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDC45 PF02724.14 RUS72305.1 - 0.43 8.8 25.3 0.6 8.3 25.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RUS72305.1 - 0.43 9.9 26.0 0.51 9.6 26.0 1.1 1 0 0 1 1 1 0 BUD22 Defensin_propep PF00879.18 RUS72305.1 - 0.52 10.6 0.0 0.52 10.6 0.0 3.4 2 1 0 2 2 1 0 Defensin propeptide RPN2_C PF18004.1 RUS72305.1 - 0.62 10.0 2.5 1 9.3 2.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop25 PF09805.9 RUS72305.1 - 1.1 9.8 13.9 1.6 9.2 13.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CNDH2_C PF16858.5 RUS72305.1 - 1.3 8.8 14.0 2.2 8.1 14.0 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1754 PF08555.10 RUS72305.1 - 2 9.3 11.6 4.3 8.2 11.6 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) NPR3 PF03666.13 RUS72305.1 - 2.3 6.9 7.3 2.8 6.6 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 RUS72305.1 - 2.7 7.3 28.9 3.7 6.9 28.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd2 PF05786.14 RUS72305.1 - 5.1 5.6 23.0 6.1 5.4 23.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 7tm_1 PF00001.21 RUS72306.1 - 8.9e-05 21.9 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS72306.1 - 9.6e-05 21.8 3.4 0.11 11.7 2.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw TMEM51 PF15345.6 RUS72306.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Orf78 PF06024.12 RUS72306.1 - 0.034 14.5 0.1 0.095 13.0 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) GET2 PF08690.10 RUS72306.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SUZ PF12752.7 RUS72306.1 - 0.2 12.4 1.6 0.77 10.6 0.0 2.2 2 0 0 2 2 2 0 SUZ domain Phage_holin_3_6 PF07332.11 RUS72306.1 - 0.83 9.7 3.8 2.2 8.3 1.6 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RVT_1 PF00078.27 RUS72307.1 - 1.9e-21 76.6 0.0 3.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PACT_coil_coil PF10495.9 RUS72307.1 - 0.025 15.2 0.6 6.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein RVT_1 PF00078.27 RUS72308.1 - 0.00062 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3365 PF11845.8 RUS72308.1 - 2.1 8.7 5.7 0.15 12.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) RVT_1 PF00078.27 RUS72309.1 - 6.9e-11 42.1 0.4 2.2e-10 40.5 0.4 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3288 PF11691.8 RUS72309.1 - 0.064 13.3 0.2 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) H_lectin PF09458.10 RUS72310.1 - 0.064 13.4 0.2 0.19 11.9 0.2 1.8 1 0 0 1 1 1 0 H-type lectin domain PK PF00224.21 RUS72311.1 - 1.5e-82 277.3 7.3 1.6e-82 277.2 7.3 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 RUS72311.1 - 1.5e-05 24.2 1.0 2.9e-05 23.3 1.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Complex1_49kDa PF00346.19 RUS72312.1 - 7.3e-129 428.6 0.0 9.3e-129 428.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 RUS72312.1 - 0.00033 19.7 0.0 0.00084 18.3 0.0 1.6 1 1 1 2 2 2 1 Nickel-dependent hydrogenase DDE_3 PF13358.6 RUS72314.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 RUS72314.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Mpp10 PF04006.12 RUS72314.1 - 0.0051 15.3 12.3 0.006 15.1 12.3 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 RUS72314.1 - 0.018 14.4 10.7 0.023 14.1 10.7 1.2 1 0 0 1 1 1 0 BUD22 Nop25 PF09805.9 RUS72314.1 - 0.019 15.4 5.8 0.032 14.7 5.8 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2457 PF10446.9 RUS72314.1 - 0.021 14.0 35.2 0.029 13.5 35.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 RUS72314.1 - 0.039 12.7 0.6 0.042 12.7 0.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.12 RUS72314.1 - 0.042 12.2 3.9 0.048 12.0 3.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1754 PF08555.10 RUS72314.1 - 0.049 14.4 3.4 0.082 13.7 3.4 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DNA_pol_phi PF04931.13 RUS72314.1 - 0.11 10.6 37.7 0.14 10.2 37.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS72314.1 - 0.3 9.6 19.2 0.38 9.3 19.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 RUS72314.1 - 0.31 10.9 9.8 0.46 10.3 9.8 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 RUS72314.1 - 0.63 10.3 5.7 0.93 9.8 5.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.16 RUS72314.1 - 0.87 8.7 10.2 1.2 8.3 10.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Roughex PF06020.11 RUS72314.1 - 0.88 8.6 9.7 1.1 8.2 9.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 RUS72314.1 - 0.95 7.6 26.1 1.2 7.3 26.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS72314.1 - 1.3 7.2 22.4 1.7 6.8 22.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2796 PF10986.8 RUS72314.1 - 2 8.4 5.3 3 7.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Sigma70_ner PF04546.13 RUS72314.1 - 2.4 8.0 19.2 4.1 7.2 19.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 RUS72314.1 - 2.8 7.3 24.4 3.7 6.9 24.4 1.1 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 RUS72314.1 - 3 7.7 5.3 78 3.1 5.2 2.6 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain IFT57 PF10498.9 RUS72314.1 - 6.4 5.6 11.0 9.5 5.1 11.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Bestrophin PF01062.21 RUS72315.1 - 1.6e-87 293.7 0.6 1.9e-87 293.4 0.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Rrn6 PF10214.9 RUS72315.1 - 0.033 12.7 5.8 0.044 12.3 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CCDC24 PF15669.5 RUS72315.1 - 0.2 11.5 3.1 0.28 11.1 3.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SSP160 PF06933.11 RUS72315.1 - 1.3 7.1 14.2 1.8 6.6 14.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tetraspanin PF00335.20 RUS72318.1 - 5.7e-22 78.6 10.9 2.6e-21 76.4 10.9 1.8 1 1 0 1 1 1 1 Tetraspanin family Shisa PF13908.6 RUS72318.1 - 6.8e-05 23.2 9.5 0.0062 16.8 2.8 2.2 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 RUS72318.1 - 0.25 9.7 0.5 0.34 9.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tetraspanin PF00335.20 RUS72319.1 - 3.2e-12 46.7 2.0 3.4e-12 46.6 2.0 1.0 1 0 0 1 1 1 1 Tetraspanin family DRMBL PF07522.14 RUS72320.1 - 6.3e-16 58.5 0.5 1.2e-06 28.7 0.0 2.8 2 0 0 2 2 2 2 DNA repair metallo-beta-lactamase RMMBL PF07521.12 RUS72320.1 - 9.3e-06 25.5 0.0 0.15 12.0 0.0 3.4 3 0 0 3 3 3 2 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RUS72320.1 - 3.7e-05 23.3 0.0 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_22 PF13383.6 RUS72321.1 - 0.0048 16.5 0.1 0.0075 15.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.29 RUS72322.1 - 9.9e-47 158.9 0.1 3.6e-46 157.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS72322.1 - 8.6e-28 96.9 0.0 2e-26 92.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 RUS72322.1 - 0.0028 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 RUS72322.1 - 0.0042 17.4 1.0 0.19 12.0 0.9 3.0 2 1 0 2 2 2 1 AAA domain MCM2_N PF12619.8 RUS72322.1 - 0.16 12.2 4.6 0.29 11.4 4.6 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Ank_5 PF13857.6 RUS72323.1 - 7.4e-21 73.9 1.2 4e-09 36.6 0.5 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS72323.1 - 3e-19 69.4 0.2 4.4e-06 27.2 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS72323.1 - 6.7e-16 56.8 0.8 6.4e-05 23.1 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RUS72323.1 - 1.8e-13 50.2 1.4 0.0011 19.4 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 RUS72323.1 - 1e-12 48.3 0.0 8.9e-08 32.5 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Glyco_hydro_20b PF02838.15 RUS72323.1 - 4.2e-07 30.8 0.0 1.1e-06 29.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 RUS72323.1 - 0.033 13.6 0.0 0.44 9.9 0.0 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 20, catalytic domain DUF5465 PF17553.2 RUS72323.1 - 0.44 11.2 2.6 2.1 9.1 1.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5465) Glyco_hydro_3_C PF01915.22 RUS72324.1 - 1.4e-43 149.3 0.0 2e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RUS72324.1 - 4.8e-38 131.3 0.0 1.2e-37 130.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RUS72324.1 - 8.1e-11 41.9 0.0 2.3e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain MARVEL PF01284.23 RUS72325.1 - 0.00013 22.1 19.0 0.00033 20.7 19.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain Siva PF05458.12 RUS72326.1 - 1.2e-25 90.2 22.5 3.4e-16 59.4 0.1 2.2 2 0 0 2 2 2 2 Cd27 binding protein (Siva) STAC2_u1 PF16664.5 RUS72326.1 - 0.97 9.9 7.4 0.18 12.3 1.1 2.2 2 1 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 VWA PF00092.28 RUS72327.1 - 2e-91 305.0 2.4 2.1e-39 135.5 0.1 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS72327.1 - 4.7e-29 101.2 0.6 6e-14 52.6 0.0 4.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 RUS72327.1 - 2.4e-13 50.3 0.3 2.7e-05 24.2 0.0 3.9 3 2 2 5 5 5 2 von Willebrand factor type A domain GGDEF_2 PF17853.1 RUS72327.1 - 5.2e-05 23.5 0.1 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 1 GGDEF-like domain Radical_SAM PF04055.21 RUS72327.1 - 0.037 14.4 0.1 68 3.8 0.0 3.6 3 0 0 3 3 3 0 Radical SAM superfamily Copine PF07002.16 RUS72327.1 - 0.037 13.5 0.0 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Copine KAR9 PF08580.10 RUS72327.1 - 2.7 6.5 19.7 5.1 5.5 19.7 1.5 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Thioredoxin PF00085.20 RUS72328.1 - 2.6e-10 40.2 0.1 3e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS72328.1 - 0.0012 19.1 0.2 0.008 16.5 0.1 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RUS72328.1 - 0.0093 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RUS72328.1 - 0.0097 15.8 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family LppC PF04348.13 RUS72328.1 - 0.095 11.5 0.0 0.095 11.5 0.0 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Peptidase_M13 PF01431.21 RUS72329.1 - 3.8e-44 150.8 0.0 4.2e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Dimer_Tnp_hAT PF05699.14 RUS72330.1 - 0.042 13.6 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Ion_trans_2 PF07885.16 RUS72331.1 - 1.8e-33 114.4 20.2 5.7e-19 67.9 0.6 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS72331.1 - 5e-05 22.7 0.3 5e-05 22.7 0.3 2.4 2 1 0 2 2 2 1 Ion transport protein SPC25 PF06703.11 RUS72331.1 - 0.96 9.2 6.1 4.5 7.0 1.3 2.8 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Fringe PF02434.16 RUS72332.1 - 2.3e-63 214.0 0.0 2.9e-53 180.9 0.0 2.1 2 0 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 RUS72332.1 - 0.0017 18.2 0.0 24 4.7 0.0 3.6 3 1 0 4 4 4 3 Galactosyltransferase DUF604 PF04646.12 RUS72332.1 - 0.044 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 HLH PF00010.26 RUS72334.1 - 1.5e-16 60.1 0.5 1.5e-16 60.1 0.5 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain fragilysinNterm PF16376.5 RUS72334.1 - 0.078 12.7 2.4 0.17 11.6 2.4 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin Tmem26 PF09772.9 RUS72335.1 - 1.3e-70 238.1 11.8 1.7e-70 237.7 11.8 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 GPI2 PF06432.11 RUS72335.1 - 0.0098 15.4 4.2 0.0098 15.4 4.2 2.4 2 1 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2069 PF09842.9 RUS72335.1 - 0.011 16.0 1.3 0.033 14.4 1.3 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) Enkurin PF13864.6 RUS72336.1 - 6.3e-26 90.7 1.3 6.3e-26 90.7 1.3 2.3 2 0 0 2 2 2 1 Calmodulin-binding DUF4639 PF15479.6 RUS72337.1 - 7.2e-39 134.2 14.2 3.7e-36 125.2 8.8 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4639) Amidase_2 PF01510.25 RUS72338.1 - 0.0071 16.8 0.0 0.0093 16.4 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Pkinase PF00069.25 RUS72340.1 - 5.6e-57 193.1 0.0 6.6e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72340.1 - 2.4e-39 135.2 0.0 3e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS72340.1 - 0.00014 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS72340.1 - 0.00021 20.3 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS72340.1 - 0.0014 17.5 0.1 0.0085 14.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RUS72340.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS72340.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 RUS72340.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4344 PF14247.6 RUS72340.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase Tweety PF04906.13 RUS72341.1 - 2e-63 214.5 5.7 2.3e-63 214.3 5.7 1.0 1 0 0 1 1 1 1 Tweety Prominin PF05478.11 RUS72341.1 - 7e-06 24.3 7.2 0.00019 19.6 0.0 3.2 2 1 1 3 3 3 2 Prominin Pex24p PF06398.11 RUS72341.1 - 1e-05 24.7 0.4 0.0019 17.3 0.3 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF2207 PF09972.9 RUS72341.1 - 0.00019 20.3 1.0 1.9 7.1 0.1 3.1 3 0 0 3 3 3 3 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 RUS72341.1 - 0.00038 20.4 0.0 0.059 13.3 0.0 3.0 3 0 0 3 3 3 1 TMEM154 protein family TctB PF07331.11 RUS72341.1 - 0.00079 19.7 13.8 0.55 10.5 8.9 3.1 3 0 0 3 3 3 2 Tripartite tricarboxylate transporter TctB family ETRAMP PF09716.10 RUS72341.1 - 0.016 15.2 0.3 1.7 8.7 0.1 3.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DPM3 PF08285.11 RUS72341.1 - 0.1 12.8 0.1 0.1 12.8 0.1 4.0 4 1 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Orf78 PF06024.12 RUS72341.1 - 0.21 11.9 3.2 0.32 11.3 0.1 2.7 3 0 0 3 3 3 0 Orf78 (ac78) RDD PF06271.12 RUS72341.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.7 4 0 0 4 4 3 0 RDD family Ninjurin PF04923.12 RUS72341.1 - 0.82 9.6 3.8 1.3 9.0 0.1 2.8 3 0 0 3 3 3 0 Ninjurin DUF1461 PF07314.11 RUS72341.1 - 1.2 9.0 7.9 1.4 8.8 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) SH3_1 PF00018.28 RUS72342.1 - 2.2e-33 113.6 0.8 9.7e-16 57.1 0.2 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 RUS72342.1 - 4.2e-30 103.4 0.1 2.4e-16 59.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 RUS72342.1 - 3.3e-24 84.3 0.0 2e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 RUS72342.1 - 6.3e-16 58.3 0.1 1.5e-15 57.0 0.1 1.6 1 1 0 1 1 1 1 SH2 domain TUDOR PF00567.24 RUS72342.1 - 0.0044 17.0 0.0 1.7 8.7 0.0 2.6 2 1 1 3 3 3 2 Tudor domain Mito_carr PF00153.27 RUS72343.1 - 3.9e-43 145.3 0.2 2.4e-21 75.5 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein MIF PF01187.18 RUS72343.1 - 0.0067 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Serine_protease PF18405.1 RUS72343.1 - 0.029 13.5 0.1 0.051 12.7 0.1 1.4 1 1 0 1 1 1 0 Gammaproteobacterial serine protease CSD PF00313.22 RUS72344.1 - 3.2e-11 42.9 0.1 7.4e-11 41.7 0.3 1.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RUS72344.1 - 0.00094 18.8 0.3 0.0036 16.9 0.3 1.9 1 1 0 1 1 1 1 Ribonuclease B OB domain PMM PF03332.13 RUS72345.1 - 9.7e-103 342.7 0.3 1.1e-102 342.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 RUS72345.1 - 0.00042 20.2 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PqqD PF05402.12 RUS72345.1 - 0.092 13.1 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Peptidase_A22B PF04258.13 RUS72346.1 - 5.1e-96 321.5 9.4 6.9e-96 321.1 9.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 RUS72346.1 - 0.00045 19.8 5.4 0.00045 19.8 5.4 2.0 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 RUS72346.1 - 0.18 10.5 8.4 0.016 14.0 2.4 2.1 2 1 1 3 3 3 0 Presenilin C9orf72-like PF15019.6 RUS72347.1 - 4.9e-45 154.0 0.0 6.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 C9orf72-like protein family Vault_3 PF17795.1 RUS72351.1 - 0.015 15.3 0.0 0.5 10.4 0.0 2.7 2 0 0 2 2 2 0 Major Vault Protein Repeat domain DUF3301 PF11743.8 RUS72351.1 - 0.12 12.1 0.6 0.43 10.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) GalKase_gal_bdg PF10509.9 RUS72352.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Amino_oxidase PF01593.24 RUS72353.1 - 1.3e-35 123.6 0.0 1.5e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Orthoreo_P17 PF07272.11 RUS72353.1 - 0.027 14.5 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Orthoreovirus P17 protein NAD_binding_8 PF13450.6 RUS72354.1 - 8.8e-12 45.1 0.1 7.3e-11 42.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 RUS72354.1 - 3.7e-11 43.0 0.9 7.8e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 RUS72354.1 - 1.2e-06 27.9 0.9 2.3e-06 27.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RUS72354.1 - 1.9e-06 27.8 0.9 3.4e-06 26.9 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS72354.1 - 4e-05 23.0 0.3 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RUS72354.1 - 0.00027 20.4 0.1 0.00027 20.4 0.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS72354.1 - 0.00055 20.4 0.3 0.0015 19.0 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RUS72354.1 - 0.001 18.4 0.7 0.001 18.4 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 RUS72354.1 - 0.0013 18.1 0.2 0.0025 17.1 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 RUS72354.1 - 0.002 17.4 0.3 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS72354.1 - 0.0029 16.4 0.1 0.0029 16.4 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 RUS72354.1 - 0.004 16.3 1.7 0.0061 15.7 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RUS72354.1 - 0.013 14.6 0.2 0.024 13.7 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 RUS72354.1 - 0.016 15.2 0.1 0.053 13.5 0.1 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 RUS72354.1 - 0.03 13.6 2.3 0.083 12.2 2.3 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RUS72354.1 - 0.043 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GSIII_N PF12437.8 RUS72354.1 - 0.06 13.0 3.1 16 5.2 0.1 4.0 1 1 3 4 4 4 0 Glutamine synthetase type III N terminal ThiF PF00899.21 RUS72354.1 - 0.077 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Rad17 PF03215.15 RUS72355.1 - 8e-38 130.2 0.1 3.4e-37 128.2 0.1 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 RUS72355.1 - 7.7e-05 23.1 0.0 0.00025 21.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS72355.1 - 0.00016 22.0 0.0 0.00066 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS72355.1 - 0.00092 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS72355.1 - 0.0012 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 RUS72355.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 RUS72355.1 - 0.0067 16.7 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 RUS72355.1 - 0.024 15.0 0.0 0.068 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RUS72355.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 RUS72355.1 - 0.039 14.1 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 RUS72355.1 - 0.047 14.2 1.4 0.2 12.2 0.0 2.7 2 2 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 RUS72355.1 - 0.063 13.7 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 RUS72355.1 - 0.077 13.2 0.2 0.32 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 RUS72355.1 - 0.092 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RUS72355.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TM2 PF05154.16 RUS72356.1 - 5.6e-15 55.4 3.6 1e-14 54.5 3.6 1.4 1 0 0 1 1 1 1 TM2 domain DUF2207 PF09972.9 RUS72357.1 - 0.0096 14.7 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SLATT_2 PF18183.1 RUS72357.1 - 0.044 13.6 0.9 0.35 10.6 0.2 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 RNase_J_C PF17770.1 RUS72357.1 - 0.057 14.5 2.6 0.22 12.6 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Phage_holin_6_1 PF09682.10 RUS72357.1 - 0.099 13.1 0.6 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF760 PF05542.11 RUS72357.1 - 0.19 12.1 2.6 0.82 10.1 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DUF948 PF06103.11 RUS72357.1 - 4.4 7.6 5.2 10 6.5 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EMC3_TMCO1 PF01956.16 RUS72358.1 - 4.8 6.9 5.5 10 5.8 4.3 2.0 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Vps39_2 PF10367.9 RUS72358.1 - 5 7.6 8.0 15 6.1 1.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 VWA PF00092.28 RUS72359.1 - 8e-16 58.8 0.2 1.1e-15 58.4 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS72359.1 - 4.1e-12 46.7 0.1 6.6e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS72359.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Na_Pi_cotrans PF02690.15 RUS72360.1 - 0.0054 16.8 0.7 0.0086 16.2 0.4 1.6 1 1 0 1 1 1 1 Na+/Pi-cotransporter DUF202 PF02656.15 RUS72360.1 - 0.075 13.5 0.7 3.3 8.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PhnH PF05845.12 RUS72361.1 - 0.09 12.5 0.1 0.71 9.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) CXCXC PF03128.14 RUS72362.1 - 0.014 15.8 1.1 0.014 15.8 1.1 10.2 11 0 0 11 11 11 0 CXCXC repeat CBM_14 PF01607.24 RUS72363.1 - 7.7e-09 35.6 11.1 1.4e-06 28.4 8.7 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain NCBP3 PF10309.9 RUS72364.1 - 1e-15 57.3 0.0 1.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 RUS72364.1 - 0.04 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain Fibrinogen_C PF00147.18 RUS72365.1 - 2.4e-59 200.8 5.5 2.9e-59 200.5 5.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CW_7 PF08230.11 RUS72365.1 - 0.15 11.8 0.6 0.29 10.9 0.6 1.4 1 0 0 1 1 1 0 CW_7 repeat RNase_T PF00929.24 RUS72366.1 - 3.8e-16 60.1 0.0 5.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 RUS72366.1 - 0.0002 21.1 0.0 0.00053 19.7 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Smg4_UPF3 PF03467.15 RUS72367.1 - 2.1e-52 177.6 0.0 3e-52 177.1 0.0 1.2 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_2 PF04059.12 RUS72367.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Claudin_3 PF06653.11 RUS72369.1 - 3e-13 50.0 8.0 1.8e-09 37.8 3.2 2.3 2 0 0 2 2 2 2 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 RUS72369.1 - 1.4e-12 47.8 8.3 1.6e-10 41.1 3.9 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF2298 PF10060.9 RUS72369.1 - 2e-05 23.5 7.5 0.00065 18.5 3.1 2.1 2 0 0 2 2 2 2 Uncharacterized membrane protein (DUF2298) DUF4231 PF14015.6 RUS72369.1 - 5.3e-05 23.6 14.4 0.012 16.1 2.3 3.4 2 1 2 4 4 4 2 Protein of unknown function (DUF4231) Folliculin PF11704.8 RUS72369.1 - 0.00014 21.8 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 2 Vesicle coat protein involved in Golgi to plasma membrane transport YMF19 PF02326.15 RUS72369.1 - 0.00015 22.5 1.0 0.72 10.7 0.0 2.5 2 1 0 2 2 2 2 Plant ATP synthase F0 Rhabdo_glycop PF00974.18 RUS72369.1 - 0.00021 19.9 0.4 0.39 9.1 0.0 2.1 2 0 0 2 2 2 2 Rhabdovirus spike glycoprotein DUF2339 PF10101.9 RUS72369.1 - 0.00029 19.6 2.6 0.00057 18.6 2.6 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2339) NrsF PF06532.11 RUS72369.1 - 0.00065 19.5 9.4 0.051 13.3 4.7 2.9 3 0 0 3 3 3 2 Negative regulator of sigma F ANKH PF07260.11 RUS72369.1 - 0.00071 18.9 1.0 0.078 12.1 0.6 2.1 2 0 0 2 2 2 1 Progressive ankylosis protein (ANKH) SLATT_4 PF18186.1 RUS72369.1 - 0.0016 18.2 1.1 1.6 8.3 0.1 2.4 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 4 Nucleoside_tran PF01733.18 RUS72369.1 - 0.0034 16.8 0.1 2 7.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoside transporter HlyIII PF03006.20 RUS72369.1 - 0.0095 15.7 3.7 0.022 14.5 1.3 2.3 2 1 0 2 2 2 1 Haemolysin-III related TMEM37 PF15108.6 RUS72369.1 - 0.0096 15.8 3.2 0.0096 15.8 3.2 1.7 2 1 0 2 2 1 1 Voltage-dependent calcium channel gamma-like subunit protein family COX1 PF00115.20 RUS72369.1 - 0.02 13.8 7.5 0.061 12.2 2.9 2.1 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Acyl_transf_3 PF01757.22 RUS72369.1 - 0.021 13.9 2.8 0.13 11.3 1.4 2.1 2 0 0 2 2 2 0 Acyltransferase family Claudin_2 PF13903.6 RUS72369.1 - 0.024 14.4 24.6 1.2 8.9 15.9 4.0 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 RUS72369.1 - 0.03 13.8 15.9 0.74 9.2 0.1 3.2 2 1 1 3 3 3 0 Clc-like PepSY_TM PF03929.16 RUS72369.1 - 0.049 13.3 3.5 0.54 9.9 1.2 2.8 1 1 2 3 3 3 0 PepSY-associated TM region Amastin PF07344.11 RUS72369.1 - 0.13 12.1 6.0 0.04 13.8 1.9 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein Abhydrolase_9_N PF15420.6 RUS72369.1 - 0.18 11.8 6.5 11 5.9 2.1 2.4 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus CitMHS PF03600.16 RUS72369.1 - 0.22 10.7 8.8 0.79 8.9 9.2 1.6 1 1 0 1 1 1 0 Citrate transporter SUR7 PF06687.12 RUS72369.1 - 0.26 10.9 4.7 2.5 7.7 0.2 2.6 1 1 1 2 2 2 0 SUR7/PalI family DUF1198 PF06711.11 RUS72369.1 - 0.65 10.0 7.1 7.4 6.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) DUF2207 PF09972.9 RUS72369.1 - 0.75 8.5 11.8 0.23 10.2 4.2 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) EI24 PF07264.11 RUS72369.1 - 0.97 9.7 9.4 11 6.3 9.6 2.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF998 PF06197.13 RUS72369.1 - 1.3 8.6 11.2 0.056 13.0 3.1 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF998) FtsH_ext PF06480.15 RUS72369.1 - 1.4 9.3 3.0 41 4.6 0.0 2.9 2 0 0 2 2 2 0 FtsH Extracellular SpoIIIAC PF06686.11 RUS72369.1 - 1.9 8.7 13.5 5.4 7.3 0.3 3.6 2 1 0 2 2 2 0 Stage III sporulation protein AC/AD protein family ABC2_membrane_3 PF12698.7 RUS72369.1 - 2 7.5 6.3 8.3 5.4 0.1 2.4 2 1 1 3 3 3 0 ABC-2 family transporter protein Atthog PF18800.1 RUS72369.1 - 2.7 7.9 8.5 11 5.9 1.5 2.6 2 1 0 2 2 2 0 Attenuator of Hedgehog Dicty_CAR PF05462.11 RUS72369.1 - 6.5 5.8 7.4 16 4.5 0.3 2.9 2 1 1 3 3 3 0 Slime mold cyclic AMP receptor Wzy_C PF04932.15 RUS72369.1 - 7.2 6.2 15.5 6.3 6.4 0.5 3.1 1 1 3 4 4 4 0 O-Antigen ligase Mucin15 PF15672.5 RUS72371.1 - 0.00053 19.6 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 PTP_tm PF18861.1 RUS72371.1 - 0.0016 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Saf_2TM PF18303.1 RUS72371.1 - 0.0052 16.4 0.0 0.0065 16.1 0.0 1.1 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain Gly-zipper_Omp PF13488.6 RUS72371.1 - 0.0085 16.1 0.7 0.013 15.5 0.7 1.2 1 0 0 1 1 1 1 Glycine zipper DUF5305 PF17231.2 RUS72371.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BatD PF13584.6 RUS72371.1 - 0.053 12.3 0.0 0.059 12.2 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF2407_C PF13373.6 RUS72371.1 - 0.088 13.0 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain LapA_dom PF06305.11 RUS72371.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MAM PF00629.23 RUS72372.1 - 7e-10 39.1 0.0 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu MAM PF00629.23 RUS72373.1 - 0.0051 16.7 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu FlaC_arch PF05377.11 RUS72374.1 - 0.00022 21.6 1.4 0.16 12.4 0.0 3.8 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 RUS72374.1 - 0.0025 17.9 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 RUS72374.1 - 0.0025 17.9 0.7 0.12 12.4 0.4 2.4 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 RUS72374.1 - 0.0083 16.1 1.0 0.055 13.4 0.1 2.4 2 1 1 3 3 3 1 Prefoldin subunit XhlA PF10779.9 RUS72374.1 - 0.014 15.6 0.9 1.8 8.8 0.1 3.0 3 0 0 3 3 3 0 Haemolysin XhlA K-box PF01486.17 RUS72374.1 - 0.04 14.1 0.2 0.095 12.9 0.2 1.6 1 0 0 1 1 1 0 K-box region NPV_P10 PF05531.12 RUS72374.1 - 0.091 13.2 1.1 6.9 7.2 0.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.13 RUS72374.1 - 0.1 13.0 0.2 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Apolipoprotein PF01442.18 RUS72374.1 - 0.14 12.1 0.9 0.26 11.2 0.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 RUS72374.1 - 0.15 12.7 0.1 0.63 10.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YvrJ PF12841.7 RUS72374.1 - 0.18 11.4 1.1 2.5 7.7 0.1 2.6 2 0 0 2 2 2 0 YvrJ protein family CLZ PF16526.5 RUS72374.1 - 0.23 11.8 2.7 0.77 10.2 2.7 1.8 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HalX PF08663.10 RUS72374.1 - 0.43 10.9 2.2 2 8.8 0.6 2.3 1 1 1 2 2 2 0 HalX domain HSBP1 PF06825.12 RUS72374.1 - 0.48 10.3 3.6 12 5.8 0.2 3.7 3 1 1 4 4 4 0 Heat shock factor binding protein 1 RRM_1 PF00076.22 RUS72375.1 - 2.3e-84 277.2 6.1 1.6e-20 72.7 0.1 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 RUS72375.1 - 1.5e-31 108.3 1.1 2.2e-30 104.6 1.7 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 RUS72375.1 - 1.2e-09 37.8 0.0 0.18 11.4 0.0 4.3 1 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS72375.1 - 4e-07 29.9 0.6 1.3 9.1 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 RUS72375.1 - 1.2e-05 25.3 0.4 9.8 6.3 0.0 4.4 4 0 0 4 4 4 3 Limkain b1 DUF4523 PF15023.6 RUS72375.1 - 9.1e-05 22.3 0.0 6.2 6.6 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF4523) RRM_7 PF16367.5 RUS72375.1 - 0.00017 21.7 0.5 1.8 8.7 0.0 5.0 4 4 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 RUS72375.1 - 0.00017 21.4 0.0 0.049 13.5 0.0 3.8 4 1 0 4 4 4 1 Occluded RNA-recognition motif RRM_3 PF08777.11 RUS72375.1 - 0.00032 20.7 3.5 0.85 9.7 0.3 4.0 3 1 1 4 4 4 1 RNA binding motif SET_assoc PF11767.8 RUS72375.1 - 0.00076 19.1 0.0 25 4.6 0.0 4.3 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DUF4078 PF13300.6 RUS72375.1 - 0.16 12.3 6.7 40 4.6 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4078) OB_RNB PF08206.11 RUS72375.1 - 0.24 11.1 4.2 16 5.3 0.1 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain E2F_CC-MB PF16421.5 RUS72376.1 - 1.7e-34 118.0 0.0 3.5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 RUS72376.1 - 2.8e-24 85.0 0.1 5.6e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 RUS72376.1 - 0.063 13.4 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC TLD PF07534.16 RUS72377.1 - 2.2e-35 121.9 0.8 4.5e-35 120.9 0.4 1.8 2 0 0 2 2 2 1 TLD LysM PF01476.20 RUS72377.1 - 3.1e-07 30.4 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain GRAM PF02893.20 RUS72377.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Dicty_REP PF05086.12 RUS72377.1 - 3.3 5.6 3.8 4.8 5.0 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2076 PF09849.9 RUS72378.1 - 0.0004 20.5 24.9 0.0004 20.5 24.9 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DnaJ-X PF14308.6 RUS72378.1 - 0.0028 17.1 4.9 0.0028 17.1 4.9 3.0 2 1 0 2 2 1 1 X-domain of DnaJ-containing TraV PF09676.10 RUS72378.1 - 0.0048 17.9 2.2 0.0048 17.9 2.2 2.4 2 1 0 2 2 2 1 Type IV conjugative transfer system lipoprotein (TraV) Plasmodium_Vir PF05795.11 RUS72378.1 - 0.0077 15.7 25.2 0.18 11.2 1.7 2.0 2 0 0 2 2 2 2 Plasmodium vivax Vir protein DUF3408 PF11888.8 RUS72378.1 - 0.03 14.4 37.1 0.15 12.2 18.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CCSAP PF15748.5 RUS72378.1 - 0.038 14.2 32.2 0.3 11.2 18.1 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SpoIIP PF07454.11 RUS72378.1 - 0.079 12.4 35.6 0.41 10.1 19.7 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Coilin_N PF15862.5 RUS72378.1 - 0.24 11.2 29.6 0.27 11.1 0.4 2.2 2 0 0 2 2 2 0 Coilin N-terminus G0-G1_switch_2 PF15103.6 RUS72378.1 - 1.3 9.4 24.2 0.76 10.2 9.3 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 Connexin PF00029.19 RUS72378.1 - 1.3 8.7 29.8 1.1 8.9 4.9 2.1 2 0 0 2 2 2 0 Connexin OATP PF03137.20 RUS72378.1 - 1.5 7.0 10.9 2.6 6.2 0.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 RUS72378.1 - 1.5 8.8 21.2 1.4 8.8 10.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 RUS72378.1 - 1.8 8.6 18.3 3.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family BUD22 PF09073.10 RUS72378.1 - 1.9 7.7 67.7 1.6 8.0 42.5 2.0 2 0 0 2 2 2 0 BUD22 CLN3 PF02487.17 RUS72378.1 - 1.9 7.4 21.1 1.4 7.9 1.8 2.0 2 0 0 2 2 2 0 CLN3 protein Neur_chan_memb PF02932.16 RUS72378.1 - 2 8.4 14.3 12 5.9 0.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FAM76 PF16046.5 RUS72378.1 - 2.2 7.5 21.5 4.5 6.5 1.5 2.0 2 0 0 2 2 2 0 FAM76 protein Peroxin-13_N PF04088.13 RUS72378.1 - 3.4 7.9 12.7 8.3 6.7 0.5 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SLC12 PF03522.15 RUS72378.1 - 3.5 6.6 27.8 0.87 8.5 16.1 2.0 2 0 0 2 2 2 0 Solute carrier family 12 CSRNP_N PF16019.5 RUS72378.1 - 4.2 7.2 30.4 1.6 8.6 16.6 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF262 PF03235.14 RUS72378.1 - 5.5 7.1 21.0 7.9 6.6 11.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF262 CSG2 PF16965.5 RUS72378.1 - 5.8 5.8 15.6 6.8 5.5 7.4 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator DUF4045 PF13254.6 RUS72378.1 - 6.1 6.4 27.9 0.73 9.4 12.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) MID_MedPIWI PF18296.1 RUS72378.1 - 8.9 6.0 15.2 16 5.2 0.2 2.1 2 0 0 2 2 2 0 MID domain of medPIWI DND1_DSRM PF14709.7 RUS72379.1 - 0.008 16.4 2.3 10 6.5 0.1 3.5 1 1 3 4 4 4 4 double strand RNA binding domain from DEAD END PROTEIN 1 EHN PF06441.12 RUS72379.1 - 0.028 14.8 17.3 1.8 9.0 0.8 4.2 1 1 3 4 4 4 0 Epoxide hydrolase N terminus DUF3760 PF12586.8 RUS72379.1 - 9.2 6.5 18.0 21 5.4 1.2 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3760) 5-FTHF_cyc-lig PF01812.20 RUS72380.1 - 1.1e-30 106.9 0.1 1.1e-30 106.9 0.1 2.1 2 1 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 RUS72380.1 - 2.9e-06 27.0 0.0 9.6e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.20 RUS72381.1 - 2.7e-22 78.8 0.0 5.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 RUS72381.1 - 3.4e-20 71.8 0.3 9.5e-20 70.4 0.3 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 RUS72381.1 - 3e-19 69.4 10.7 3e-19 69.4 10.7 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Maff2 PF12750.7 RUS72381.1 - 0.048 13.5 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Maff2 family EGF PF00008.27 RUS72382.1 - 0.0027 17.9 4.4 0.0052 17.1 4.4 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_3 PF12947.7 RUS72382.1 - 0.11 12.7 3.7 0.2 11.9 3.7 1.4 1 0 0 1 1 1 0 EGF domain EGF_CA PF07645.15 RUS72382.1 - 0.3 11.3 4.6 0.52 10.6 4.6 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain HTH_Tnp_Tc3_2 PF01498.18 RUS72383.1 - 3e-05 24.2 0.2 5.7e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS72383.1 - 0.00022 21.8 0.1 0.0012 19.5 0.1 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS72383.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS72383.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS72383.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 RUS72383.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF4817 PF16087.5 RUS72383.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS72383.1 - 0.074 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 RUS72383.1 - 0.077 12.8 0.6 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RUS72383.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Glyco_hydro_59 PF02057.15 RUS72384.1 - 4e-117 390.7 4.2 5e-117 390.3 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 RUS72384.1 - 2.1e-44 150.4 0.0 4.1e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Glyco_hydro_30 PF02055.16 RUS72384.1 - 0.014 14.4 0.0 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_57 PF03065.15 RUS72384.1 - 0.1 11.8 0.3 0.2 10.8 0.3 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_hydro_59 PF02057.15 RUS72385.1 - 2.1e-115 385.0 3.2 2.7e-115 384.6 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 RUS72385.1 - 7.3e-42 142.2 0.0 1.6e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Glyco_hydro_30 PF02055.16 RUS72385.1 - 0.022 13.7 0.3 0.059 12.3 0.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain PIG-P PF08510.12 RUS72386.1 - 1.5e-33 115.3 7.0 1.8e-33 115.0 7.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 RUS72386.1 - 0.00094 19.4 11.4 0.002 18.4 11.4 1.5 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF1279 PF06916.13 RUS72386.1 - 0.025 15.1 0.8 0.049 14.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Phage_holin_3_6 PF07332.11 RUS72386.1 - 0.12 12.4 1.7 0.15 12.1 1.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_A17 PF05380.13 RUS72387.1 - 9.2e-56 188.3 0.0 1.9e-55 187.3 0.0 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 RUS72387.1 - 1.2e-29 102.3 3.5 6.4e-29 100.0 3.5 2.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 RUS72387.1 - 6.8e-11 42.3 0.0 1.6e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) rve PF00665.26 RUS72387.1 - 4.4e-08 33.3 0.0 1.2e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS72387.1 - 1.1e-06 28.7 1.0 1.1e-06 28.7 1.0 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 RUS72387.1 - 0.0099 16.5 0.0 0.036 14.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 RUS72387.1 - 0.024 14.8 0.2 0.09 13.0 0.2 2.1 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 RUS72387.1 - 0.068 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS72388.1 - 0.0019 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Glyco_transf_92 PF01697.27 RUS72389.1 - 8.2e-29 101.0 0.0 1.1e-28 100.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS72389.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Elong-fact-P_C PF09285.11 RUS72390.1 - 0.054 13.3 0.1 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Elongation factor P, C-terminal Fibrinogen_C PF00147.18 RUS72391.1 - 4.7e-52 177.0 6.9 8.4e-52 176.1 6.9 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Rep_3 PF01051.21 RUS72391.1 - 0.013 15.3 1.5 0.019 14.8 1.5 1.2 1 0 0 1 1 1 0 Initiator Replication protein ApoO PF09769.9 RUS72391.1 - 0.028 14.4 0.2 0.17 11.8 0.0 2.2 1 1 1 2 2 2 0 Apolipoprotein O DUF3150 PF11348.8 RUS72391.1 - 0.12 11.6 1.4 8.2 5.6 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3150) Baculo_PEP_C PF04513.12 RUS72391.1 - 0.62 10.1 2.8 1.6 8.8 2.5 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fibrinogen_C PF00147.18 RUS72392.1 - 2.6e-53 181.1 1.3 4.3e-53 180.4 1.3 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF1664 PF07889.12 RUS72392.1 - 0.0046 17.0 5.2 0.0098 15.9 5.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) PriC PF07445.12 RUS72392.1 - 0.023 14.7 1.9 0.043 13.7 1.9 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC Nup54 PF13874.6 RUS72392.1 - 0.027 14.6 2.4 0.11 12.7 0.3 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.20 RUS72392.1 - 0.037 13.4 5.2 0.063 12.6 5.2 1.3 1 0 0 1 1 1 0 Tropomyosin HIP1_clath_bdg PF16515.5 RUS72392.1 - 0.062 13.9 5.4 0.13 12.9 5.4 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TraF_2 PF13729.6 RUS72392.1 - 0.077 12.3 1.2 0.14 11.5 1.2 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Allexi_40kDa PF05549.11 RUS72392.1 - 0.11 11.9 3.2 0.2 11.2 3.2 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein FH2 PF02181.23 RUS72392.1 - 0.12 11.4 3.5 0.18 10.9 3.5 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Atg14 PF10186.9 RUS72392.1 - 0.13 11.4 6.1 0.2 10.7 6.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 RUS72392.1 - 0.13 12.7 5.8 0.17 12.4 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2937 PF11157.8 RUS72392.1 - 0.14 11.9 0.3 0.24 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Laminin_II PF06009.12 RUS72392.1 - 0.4 10.7 7.1 0.55 10.2 5.5 2.1 2 1 0 2 2 2 0 Laminin Domain II WXG100 PF06013.12 RUS72392.1 - 0.55 10.5 2.7 18 5.6 0.5 2.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 RUS72392.1 - 0.87 9.6 10.1 1.3 9.0 9.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 RUS72392.1 - 1.9 9.0 6.1 0.49 10.9 2.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB NPV_P10 PF05531.12 RUS72392.1 - 2.6 8.6 7.3 5.2 7.6 1.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 RUS72392.1 - 3.4 7.9 6.1 26 5.1 5.9 2.3 1 1 0 1 1 1 0 Haemolysin XhlA BshC PF10079.9 RUS72392.1 - 4.2 6.0 7.5 1.7 7.3 2.2 1.9 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC IQ PF00612.27 RUS72393.1 - 2e-06 27.1 0.5 5.9e-06 25.6 0.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Nmad5 PF18757.1 RUS72393.1 - 0.65 10.2 25.4 0.099 12.8 12.0 2.3 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 DUF3584 PF12128.8 RUS72393.1 - 0.67 7.4 43.2 0.067 10.7 35.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) COG2 PF06148.11 RUS72393.1 - 1.8 8.7 26.7 0.46 10.6 0.3 4.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 RUS72393.1 - 4 7.6 29.4 0.3 11.2 10.6 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family H_PPase PF03030.16 RUS72396.1 - 0.048 12.3 1.7 0.067 11.8 1.7 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF2172 PF09940.9 RUS72398.1 - 0.018 15.4 0.0 41 4.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2172) PHD_2 PF13831.6 RUS72399.1 - 0.0026 17.3 9.7 73 3.0 0.0 7.0 8 0 0 8 8 8 0 PHD-finger YdfZ PF14001.6 RUS72399.1 - 0.0091 16.4 11.7 18 5.8 0.4 4.9 1 1 3 5 5 5 5 YdfZ protein Hydrophobin PF01185.18 RUS72399.1 - 4.8 7.9 8.1 86 3.9 0.2 3.3 1 1 3 4 4 4 0 Fungal hydrophobin Mucin-like PF16058.5 RUS72400.1 - 2.1e-18 66.3 4.1 4.2e-12 46.0 4.3 2.1 1 1 1 2 2 2 2 Mucin-like Pentapeptide PF00805.22 RUS72400.1 - 4.4e-06 26.2 1.4 8.5 6.1 0.0 9.1 7 2 2 9 9 9 1 Pentapeptide repeats (8 copies) Asp_Arg_Hydrox PF05118.15 RUS72400.1 - 9.7e-06 25.5 12.7 4.6 7.1 1.0 6.2 1 1 6 7 7 7 3 Aspartyl/Asparaginyl beta-hydroxylase Apolipoprotein PF01442.18 RUS72400.1 - 0.0017 18.3 6.1 0.0022 17.9 6.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5583 PF17821.1 RUS72400.1 - 0.0026 17.7 3.1 5 7.1 0.0 3.5 1 1 2 3 3 3 2 Family of unknown function (DUF5583) LolB PF03550.14 RUS72400.1 - 0.12 12.5 7.5 1.4 8.9 1.0 2.6 1 1 2 3 3 3 0 Outer membrane lipoprotein LolB VIT_2 PF13757.6 RUS72400.1 - 0.85 9.6 7.7 90 3.1 4.3 3.9 1 1 2 3 3 3 0 Vault protein inter-alpha-trypsin domain Fer4_3 PF12798.7 RUS72402.1 - 1 10.4 64.5 24 6.2 2.4 9.1 3 2 3 6 6 6 0 4Fe-4S binding domain SPRR2 PF14820.6 RUS72402.1 - 3.1 8.0 46.1 11 6.2 21.0 2.6 1 1 1 2 2 2 0 Small proline-rich 2 LRR_12 PF18837.1 RUS72403.1 - 1.2 8.9 7.1 52 3.6 0.1 4.3 4 1 1 5 5 5 0 Leucine-rich repeat DUF2807 PF10988.8 RUS72404.1 - 5e-05 23.2 1.8 0.097 12.5 0.1 2.1 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain CsgG PF03783.14 RUS72404.1 - 2 7.6 7.4 25 4.0 0.2 3.9 1 1 4 5 5 5 0 Curli production assembly/transport component CsgG Reprolysin_4 PF13583.6 RUS72404.1 - 4 7.0 7.8 16 5.1 5.7 2.3 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Macoilin PF09726.9 RUS72405.1 - 1.8 7.0 4.5 1.7 7.1 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 RUS72405.1 - 2.3 6.5 5.4 2.3 6.4 5.4 1.1 1 0 0 1 1 1 0 Menin DUF4813 PF16072.5 RUS72406.1 - 2.2e-05 24.3 3.7 1.9 8.1 0.1 4.4 1 1 2 4 4 4 3 Domain of unknown function (DUF4813) MRP-S35 PF10246.9 RUS72406.1 - 0.15 12.1 6.3 1.4e+02 2.5 0.1 6.5 1 1 7 9 9 9 0 Mitochondrial ribosomal protein MRP-S35 tRNA-synt_2e PF02091.15 RUS72406.1 - 3.9 6.6 27.0 1.1 8.5 0.9 4.7 1 1 4 5 5 5 0 Glycyl-tRNA synthetase alpha subunit Branch PF02485.21 RUS72407.1 - 3.6e-33 115.1 0.0 5.2e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme FAM195 PF14799.6 RUS72408.1 - 1.4e-05 25.3 0.1 2.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 FAM195 family Metallophos PF00149.28 RUS72409.1 - 1.9e-37 129.8 0.4 2.3e-37 129.5 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS72409.1 - 7.2e-18 64.8 0.2 1.2e-17 64.1 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DNA_binding_1 PF01035.20 RUS72411.1 - 1.7e-20 72.9 0.0 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 RUS72411.1 - 0.011 16.5 0.0 0.021 15.6 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain UCH PF00443.29 RUS72412.1 - 1.2e-55 188.9 0.1 2e-55 188.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 RUS72412.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal SNF PF00209.18 RUS72413.1 - 2.3e-119 399.5 14.4 2.6e-119 399.3 14.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family HTH_36 PF13730.6 RUS72414.1 - 2.6e-23 81.7 0.0 1.5e+02 2.4 0.0 19.2 20 1 1 21 21 21 0 Helix-turn-helix domain PHTB1_C PF14728.6 RUS72414.1 - 8.1e-09 35.0 29.6 7.3 5.6 0.2 10.4 1 1 16 17 17 17 17 PTHB1 C-terminus Viral_Beta_CD PF04530.12 RUS72414.1 - 6.7e-06 26.4 10.5 3e+02 1.7 0.0 9.2 1 1 18 19 19 19 0 Viral Beta C/D like family SOSSC PF15925.5 RUS72414.1 - 0.034 15.4 54.9 47 5.4 1.5 9.3 1 1 12 13 13 13 0 SOSS complex subunit C PseudoU_synth_1 PF01416.20 RUS72416.1 - 1.6e-29 102.5 0.0 1.6e-28 99.3 0.0 2.6 3 0 0 3 3 3 1 tRNA pseudouridine synthase GLTP PF08718.11 RUS72417.1 - 4.5e-28 98.4 0.4 6.1e-28 98.0 0.4 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SPOB_a PF14689.6 RUS72417.1 - 0.043 13.5 0.7 15 5.4 0.0 3.0 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain Extensin_2 PF04554.13 RUS72418.1 - 4.5 7.4 25.7 2.4 8.3 10.2 2.9 2 0 0 2 2 2 0 Extensin-like region SRP72 PF08492.12 RUS72418.1 - 5.3 7.6 7.3 3.2 8.3 0.3 3.1 3 1 0 3 3 3 0 SRP72 RNA-binding domain IER PF05760.12 RUS72419.1 - 0.0079 16.5 3.6 0.0079 16.5 3.6 1.7 2 0 0 2 2 2 1 Immediate early response protein (IER) dsrm PF00035.26 RUS72419.1 - 0.008 16.9 0.1 0.02 15.6 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 RUS72419.1 - 0.0081 16.3 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain LIX1 PF14954.6 RUS72419.1 - 0.012 14.9 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Limb expression 1 LEP503 PF15221.6 RUS72419.1 - 0.082 13.3 0.4 0.18 12.1 0.4 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Roughex PF06020.11 RUS72419.1 - 0.84 8.7 4.6 1.6 7.8 4.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein STIL_N PF15253.6 RUS72419.1 - 1.1 8.2 5.3 0.094 11.6 0.6 1.6 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus Suf PF05843.14 RUS72419.1 - 2 8.3 7.0 2.3 8.1 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Drc1-Sld2 PF11719.8 RUS72419.1 - 6.4 6.2 12.4 13 5.2 12.3 1.5 1 1 0 1 1 1 0 DNA replication and checkpoint protein RVT_3 PF13456.6 RUS72420.1 - 3e-06 27.1 0.0 0.0072 16.1 0.1 2.3 2 0 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.24 RUS72420.1 - 0.00012 22.2 0.0 0.063 13.5 0.0 2.4 2 0 0 2 2 2 2 RNase H IRK PF01007.20 RUS72421.1 - 1.2e-73 245.5 7.0 1.3e-42 144.9 0.6 2.2 1 1 1 2 2 2 2 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 RUS72421.1 - 1.6e-41 141.8 0.0 2.5e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 RUS72421.1 - 2.3e-08 33.9 17.0 0.00048 20.0 4.2 2.9 2 2 0 2 2 2 2 Ion channel Ion_trans PF00520.31 RUS72421.1 - 0.03 13.6 9.7 0.82 8.8 1.5 2.4 1 1 0 2 2 2 0 Ion transport protein DUF2182 PF09948.9 RUS72421.1 - 0.061 13.2 5.3 0.8 9.6 0.6 2.4 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) SPRY PF00622.28 RUS72422.1 - 1.4e-17 63.9 0.0 4.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 RUS72422.1 - 0.14 12.6 3.0 0.27 11.6 3.0 1.5 1 0 0 1 1 1 0 SOCS box Xpo1 PF08389.12 RUS72423.1 - 2.4e-17 63.4 0.2 2.4e-17 63.4 0.2 7.4 7 2 2 9 9 9 2 Exportin 1-like protein IBN_N PF03810.19 RUS72423.1 - 0.00018 21.4 3.8 0.00099 19.0 0.1 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain DCB PF16213.5 RUS72423.1 - 0.029 14.0 0.4 8.9 5.9 0.1 3.1 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 HSA PF07529.13 RUS72423.1 - 0.15 12.4 0.3 0.45 10.9 0.3 1.8 1 0 0 1 1 1 0 HSA TetR PF13972.6 RUS72423.1 - 0.46 10.2 4.8 0.95 9.2 0.1 3.8 4 0 0 4 4 4 0 Bacterial transcriptional repressor Pkinase PF00069.25 RUS72424.1 - 8.4e-73 245.0 0.0 1.4e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72424.1 - 1.7e-40 139.0 0.0 2.7e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS72424.1 - 7.4e-06 25.5 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS72424.1 - 0.003 16.5 2.1 0.003 16.5 2.1 2.6 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 RUS72424.1 - 0.029 13.7 0.5 0.055 12.8 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2577 PF10844.8 RUS72425.1 - 0.15 12.3 5.7 0.37 11.0 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Glycos_transf_2 PF00535.26 RUS72426.1 - 0.044 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 KfrB PF18790.1 RUS72426.1 - 0.11 12.7 0.0 5.3 7.4 0.0 2.3 2 0 0 2 2 2 0 KfrB protein Somatomedin_B PF01033.17 RUS72427.1 - 7.6e-07 29.4 17.6 2.2e-06 27.9 17.6 1.8 1 0 0 1 1 1 1 Somatomedin B domain ETX_MTX2 PF03318.13 RUS72428.1 - 1.1e-09 38.4 2.9 1.6e-09 37.9 2.9 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 zf-RING_2 PF13639.6 RUS72431.1 - 1.5e-14 54.1 5.6 2.5e-14 53.3 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS72431.1 - 2.1e-12 46.6 1.3 4.4e-12 45.5 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS72431.1 - 2.9e-11 43.0 5.0 5.1e-11 42.2 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS72431.1 - 3.7e-09 36.3 4.6 6.2e-09 35.6 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS72431.1 - 7.3e-08 32.2 3.7 1.2e-07 31.5 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS72431.1 - 8.4e-08 32.4 6.3 3e-07 30.6 6.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS72431.1 - 1.7e-06 27.9 2.2 9.9e-06 25.5 2.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger PA PF02225.22 RUS72431.1 - 3.9e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PA domain Prok-RING_4 PF14447.6 RUS72431.1 - 5.2e-06 26.2 3.2 9.7e-06 25.3 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RUS72431.1 - 6.8e-06 25.8 3.3 1.2e-05 25.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS72431.1 - 0.00074 19.5 1.0 0.0016 18.4 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RUS72431.1 - 0.00086 18.9 2.6 0.0017 17.9 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 RUS72431.1 - 0.0051 16.7 4.1 0.0091 15.9 4.1 1.4 1 0 0 1 1 1 1 PHD-finger SF1-HH PF16275.5 RUS72431.1 - 0.0057 17.0 0.7 0.012 16.0 0.7 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain Cadherin_C_2 PF16492.5 RUS72431.1 - 0.066 14.0 0.0 0.19 12.5 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RINGv PF12906.7 RUS72431.1 - 0.071 13.2 4.5 0.14 12.3 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.6 RUS72431.1 - 0.098 12.8 1.1 0.24 11.6 1.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3H2C3 PF17122.5 RUS72431.1 - 0.1 12.7 3.9 0.23 11.5 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 RUS72431.1 - 0.11 12.4 1.5 0.21 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4407 PF14362.6 RUS72431.1 - 0.12 11.8 1.5 0.18 11.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING-like PF08746.11 RUS72431.1 - 0.19 12.1 4.1 0.36 11.2 4.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 RUS72431.1 - 0.32 11.2 4.0 0.68 10.1 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RUS72431.1 - 0.33 11.1 4.2 1.3 9.2 4.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain AAA_11 PF13086.6 RUS72431.1 - 0.39 10.4 3.5 0.68 9.7 3.5 1.3 1 0 0 1 1 1 0 AAA domain zf-RING_4 PF14570.6 RUS72431.1 - 2 8.2 6.1 4.5 7.2 6.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 RUS72431.1 - 2.3 8.4 5.4 8.1 6.6 5.5 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger RVT_1 PF00078.27 RUS72432.1 - 2.3e-38 131.9 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 RUS72432.1 - 0.00012 21.9 4.4 0.00023 21.0 4.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS72432.1 - 0.023 14.3 0.1 0.023 14.3 0.1 2.0 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 RUS72432.1 - 0.046 13.8 0.9 0.094 12.8 0.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 RUS72432.1 - 0.14 12.0 5.9 0.27 11.1 5.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SET PF00856.28 RUS72434.1 - 1.5e-23 84.1 2.7 1.5e-22 80.8 0.1 2.8 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.16 RUS72434.1 - 3.8e-17 62.9 1.8 3.8e-17 62.9 1.8 2.3 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 RUS72434.1 - 5.1e-13 48.7 5.7 1.1e-12 47.7 5.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HMG_box PF00505.19 RUS72435.1 - 3.1e-16 59.5 1.4 9.3e-16 58.0 1.4 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS72435.1 - 2.7e-11 43.9 1.7 2.7e-11 43.9 1.7 1.9 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_6 PF13912.6 RUS72435.1 - 6e-06 26.1 11.0 0.013 15.5 4.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS72435.1 - 0.00074 20.2 15.9 0.0047 17.6 1.3 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger Nop14 PF04147.12 RUS72435.1 - 0.0009 17.6 19.2 0.0009 17.6 19.2 2.2 2 0 0 2 2 2 1 Nop14-like family zf-H2C2_2 PF13465.6 RUS72435.1 - 0.0021 18.4 3.9 0.0021 18.4 3.9 2.7 3 0 0 3 3 3 1 Zinc-finger double domain CpXC PF14353.6 RUS72435.1 - 0.0021 18.1 2.9 2.4 8.2 0.0 3.2 3 0 0 3 3 3 2 CpXC protein zf-Di19 PF05605.12 RUS72435.1 - 0.0075 16.5 1.1 0.02 15.2 1.1 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding MATalpha_HMGbox PF04769.12 RUS72435.1 - 0.036 13.4 2.8 0.064 12.6 2.8 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box zf-C2H2 PF00096.26 RUS72435.1 - 0.048 14.1 11.5 0.31 11.6 3.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_transf_9 PF01075.17 RUS72435.1 - 0.088 12.1 2.5 0.13 11.6 2.5 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Pex14_N PF04695.13 RUS72435.1 - 0.18 12.5 15.8 1.1 9.9 10.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C1_2 PF03107.16 RUS72435.1 - 0.41 11.0 4.3 1.3 9.4 1.7 2.4 1 1 1 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 RUS72435.1 - 2.9 8.1 5.0 23 5.2 0.0 2.9 3 0 0 3 3 2 0 Zinc ribbon domain DUF4987 PF16377.5 RUS72436.1 - 0.059 13.5 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function SPC12 PF06645.13 RUS72438.1 - 0.0033 17.5 0.3 0.0067 16.5 0.3 1.5 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Insulin_TMD PF17870.1 RUS72438.1 - 0.28 11.3 1.1 0.79 9.8 1.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ubiquitin PF00240.23 RUS72441.1 - 3.4e-16 58.8 0.2 4.7e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Tugs PF17840.1 RUS72441.1 - 5.4e-14 52.1 0.9 1e-13 51.2 0.9 1.5 1 0 0 1 1 1 1 Tethering Ubl4a to BAGS domain Rad60-SLD PF11976.8 RUS72441.1 - 3.6e-07 29.9 0.0 6.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 RUS72441.1 - 0.064 13.6 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4816 PF16086.5 RUS72442.1 - 0.24 11.3 45.3 1.8e+04 -32.4 45.3 7.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) DUF4769 PF15992.5 RUS72443.1 - 2.7 7.7 7.3 4.8 6.9 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) MRI PF15325.6 RUS72443.1 - 3.6 8.7 5.8 4.2 8.5 4.0 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection SRCR PF00530.18 RUS72444.1 - 2.9e-90 297.2 15.1 1.4e-26 92.9 0.3 4.8 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Trypsin PF00089.26 RUS72444.1 - 5.8e-63 212.7 0.9 1.4e-62 211.4 0.0 2.1 2 0 0 2 2 2 1 Trypsin SRCR_2 PF15494.6 RUS72444.1 - 5.8e-16 58.8 10.9 1.4e-05 25.6 0.1 4.7 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 RUS72444.1 - 1.6e-07 31.4 15.1 1.6e-07 31.4 15.1 3.7 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Hepsin-SRCR PF09272.10 RUS72444.1 - 2.7e-07 31.1 3.2 0.013 16.1 0.1 4.5 4 0 0 4 4 4 2 Hepsin, SRCR domain Lectin_C PF00059.21 RUS72444.1 - 0.0071 17.1 4.8 0.044 14.5 4.8 2.4 1 1 0 1 1 1 1 Lectin C-type domain DUF316 PF03761.15 RUS72444.1 - 0.016 14.8 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 AAA PF00004.29 RUS72445.1 - 1.6e-36 125.7 0.0 2.6e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS72445.1 - 1.4e-06 28.3 0.1 5.6e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS72445.1 - 3.9e-05 24.1 0.1 0.00089 19.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain TniB PF05621.11 RUS72445.1 - 7.1e-05 22.3 1.0 0.63 9.4 0.0 3.3 3 1 1 4 4 4 2 Bacterial TniB protein RuvB_N PF05496.12 RUS72445.1 - 0.00011 22.0 0.0 0.00033 20.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 RUS72445.1 - 0.00015 21.8 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RUS72445.1 - 0.00043 20.4 0.1 0.003 17.7 0.0 2.3 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 RUS72445.1 - 0.00048 19.7 0.3 0.34 10.5 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS72445.1 - 0.00053 20.3 0.2 0.026 14.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 RUS72445.1 - 0.00084 19.1 0.0 0.0018 18.1 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 RUS72445.1 - 0.0017 18.3 0.1 0.018 15.0 0.0 2.2 1 1 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 RUS72445.1 - 0.0022 17.4 0.2 0.005 16.3 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS72445.1 - 0.0032 17.8 0.1 0.01 16.2 0.0 2.1 2 1 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 RUS72445.1 - 0.0048 17.1 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS72445.1 - 0.0062 16.1 0.1 0.043 13.3 0.1 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 RUS72445.1 - 0.009 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS72445.1 - 0.012 16.1 0.0 0.037 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RUS72445.1 - 0.015 15.8 0.0 0.07 13.6 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 RUS72445.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 RUS72445.1 - 0.023 14.6 0.1 0.36 10.7 0.1 2.3 1 1 1 2 2 2 0 NACHT domain CPT PF07931.12 RUS72445.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 RUS72445.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 RUS72445.1 - 0.032 13.4 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 RUS72445.1 - 0.042 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RUS72445.1 - 0.095 12.4 0.0 0.47 10.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 RUS72445.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 RUS72445.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.22 RUS72445.1 - 0.12 12.4 0.1 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase PH PF00169.29 RUS72446.1 - 0.00051 20.5 0.0 0.0016 18.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 RUS72446.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.25 RUS72447.1 - 1.1e-44 152.3 0.0 1.3e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS72447.1 - 5.2e-36 124.4 0.0 6.5e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS72447.1 - 1.2e-09 38.3 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS72447.1 - 2.9e-08 33.5 0.0 3.3e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RUS72447.1 - 9.6e-07 28.9 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RUS72447.1 - 0.00028 20.4 0.0 0.00066 19.2 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS72447.1 - 0.0047 16.1 0.1 0.0081 15.3 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS72447.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RUS72447.1 - 0.016 14.2 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 RUS72447.1 - 0.048 13.2 0.1 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Mitofilin PF09731.9 RUS72448.1 - 0.59 8.9 17.6 0.96 8.2 17.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 RUS72449.1 - 0.095 11.0 11.8 0.13 10.6 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS72449.1 - 0.21 9.7 16.0 0.27 9.4 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS72449.1 - 1.3 7.2 3.2 1.2 7.3 3.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.13 RUS72449.1 - 2 8.3 15.4 3.4 7.5 15.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Amidase PF01425.21 RUS72450.1 - 3.3e-76 257.1 0.0 4.1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF5353 PF17304.2 RUS72450.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Amidase PF01425.21 RUS72451.1 - 2.1e-08 33.6 0.1 2.4e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Amidase His_Phos_1 PF00300.22 RUS72452.1 - 2.3e-18 66.6 0.0 2.5e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 RUS72453.1 - 3.4e-06 26.9 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 7tm_1 PF00001.21 RUS72454.1 - 0.077 12.3 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 RUS72456.1 - 2e-16 60.2 0.0 3.2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72456.1 - 3.5e-13 49.4 0.0 5.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pyridoxal_deC PF00282.19 RUS72457.1 - 5.8e-13 48.3 0.1 7.2e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain COLFI PF01410.18 RUS72458.1 - 4.1e-59 199.7 0.9 4.5e-59 199.6 0.9 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.18 RUS72459.1 - 4.5e-66 218.5 236.6 2.8e-09 36.6 31.8 8.1 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) Collagen PF01391.18 RUS72460.1 - 7e-101 330.0 408.2 5.3e-11 42.1 26.0 13.2 2 1 8 10 10 10 8 Collagen triple helix repeat (20 copies) VWC PF00093.18 RUS72460.1 - 0.00017 21.8 2.5 0.00026 21.3 2.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 RUS72460.1 - 0.13 12.2 3.6 0.23 11.5 3.6 1.3 1 0 0 1 1 1 0 TILa domain LRR_8 PF13855.6 RUS72461.1 - 3e-07 30.1 9.6 0.00017 21.3 0.5 2.9 2 1 1 3 3 3 2 Leucine rich repeat LIP1 PF15904.5 RUS72461.1 - 9.2e-06 25.9 1.4 6e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 LKB1 serine/threonine kinase interacting protein 1 LRR_6 PF13516.6 RUS72461.1 - 3.4e-05 23.5 0.9 1 9.6 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 RUS72461.1 - 0.00017 21.9 7.9 0.016 15.6 0.4 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS72461.1 - 0.0078 15.7 0.2 0.44 10.0 0.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 RUS72461.1 - 0.19 12.4 2.9 19 6.3 0.0 3.8 2 1 0 2 2 2 0 Leucine Rich Repeat DUF1178 PF06676.11 RUS72462.1 - 0.00058 20.3 3.2 0.0011 19.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1178) TIMELESS PF04821.14 RUS72464.1 - 1.7e-74 250.5 2.4 1.7e-74 250.5 2.4 1.5 2 0 0 2 2 2 1 Timeless protein CDRT4 PF15213.6 RUS72464.1 - 2 9.0 4.3 2.2 8.9 0.6 2.4 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein AP3D1 PF06375.11 RUS72464.1 - 2.5 8.3 7.4 0.31 11.2 1.0 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Ras PF00071.22 RUS72465.1 - 1.9e-62 209.6 0.1 2.4e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72465.1 - 5.1e-35 120.3 0.1 9.4e-35 119.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72465.1 - 4.1e-12 45.9 0.1 5.8e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS72465.1 - 1.8e-07 31.2 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS72465.1 - 0.00023 20.8 0.1 0.00099 18.7 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS72465.1 - 0.0003 20.7 0.6 0.02 14.8 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 RUS72465.1 - 0.0004 20.7 0.0 0.0046 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 RUS72465.1 - 0.004 16.5 0.0 0.0057 16.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 RUS72465.1 - 0.0083 16.5 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RUS72465.1 - 0.015 15.8 0.2 0.021 15.3 0.2 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 RUS72465.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 RUS72465.1 - 0.032 13.7 0.0 0.091 12.2 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 RUS72465.1 - 0.042 13.6 0.1 0.081 12.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 RUS72465.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain TniB PF05621.11 RUS72465.1 - 0.064 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 RUS72465.1 - 0.076 13.3 0.1 1.6 8.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 RUS72465.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain FAD-SLDH PF12318.8 RUS72465.1 - 0.081 13.0 0.2 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FeoB_N PF02421.18 RUS72465.1 - 0.082 12.4 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.15 RUS72465.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase MCM PF00493.23 RUS72465.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 RUS72465.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 RUS72465.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mito_carr PF00153.27 RUS72466.1 - 8.8e-36 121.7 4.8 2.4e-15 56.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein VPS13_C PF16909.5 RUS72467.1 - 1e-16 61.2 0.1 1.9e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 RUS72467.1 - 0.01 14.7 0.2 0.03 13.2 0.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain G-7-MTase PF12803.7 RUS72467.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SHR-BD PF06650.12 RUS72468.1 - 4.5e-13 49.2 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 DDHD PF02862.17 RUS72469.1 - 0.0013 19.0 0.4 0.0013 19.0 0.4 1.2 1 0 0 1 1 1 1 DDHD domain OATP PF03137.20 RUS72469.1 - 0.0014 17.1 4.9 0.0018 16.6 4.9 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family NPR3 PF03666.13 RUS72469.1 - 0.0027 16.6 13.4 0.0037 16.1 13.4 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF4050 PF13259.6 RUS72469.1 - 0.005 17.2 8.1 0.0087 16.4 8.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Tim54 PF11711.8 RUS72469.1 - 0.012 14.4 12.5 0.017 13.9 12.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ndc1_Nup PF09531.10 RUS72469.1 - 0.017 13.9 1.2 0.019 13.7 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 RUS72469.1 - 0.039 13.2 3.8 0.061 12.5 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TUSC2 PF15000.6 RUS72469.1 - 0.059 13.7 7.8 0.099 12.9 7.8 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 FGF-BP1 PF06473.12 RUS72469.1 - 0.11 12.3 22.1 0.18 11.6 22.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF2370 PF10176.9 RUS72469.1 - 0.33 10.6 4.3 0.55 9.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2058 PF09831.9 RUS72469.1 - 0.39 10.9 23.9 0.64 10.1 23.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) FAM176 PF14851.6 RUS72469.1 - 0.4 10.3 6.2 0.82 9.3 6.2 1.5 1 0 0 1 1 1 0 FAM176 family Eapp_C PF10238.9 RUS72469.1 - 0.52 10.4 14.1 1.2 9.3 14.1 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein TraV PF09676.10 RUS72469.1 - 1.3 10.0 13.3 2.2 9.3 13.3 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF3807 PF12720.7 RUS72469.1 - 1.4 9.1 27.1 2.6 8.3 27.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2828 PF11443.8 RUS72469.1 - 1.5 6.8 20.5 2 6.4 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF810 PF05664.11 RUS72469.1 - 1.6 7.1 12.1 2 6.8 12.1 1.1 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) CPSF100_C PF13299.6 RUS72469.1 - 4.4 7.4 19.6 7 6.8 19.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RP-C_C PF11800.8 RUS72469.1 - 5.6 7.0 8.5 8.8 6.4 8.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.12 RUS72469.1 - 7.4 6.3 24.9 11 5.7 24.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Utp13 PF08625.11 RUS72473.1 - 0.19 11.6 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Defensin_4 PF07936.12 RUS72474.1 - 0.11 12.4 0.9 0.11 12.4 0.9 2.0 2 0 0 2 2 2 0 Potassium-channel blocking toxin CRAL_TRIO_2 PF13716.6 RUS72475.1 - 6.2e-23 81.5 0.1 6.7e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2810 PF10928.8 RUS72475.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) DHH PF01368.20 RUS72477.1 - 0.0029 17.8 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 DHH family Collagen PF01391.18 RUS72478.1 - 0.00082 19.1 16.6 0.00082 19.1 16.6 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Herpes_UL35 PF04496.12 RUS72479.1 - 2.9 8.3 5.0 18 5.7 0.3 2.4 1 1 0 2 2 2 0 Herpesvirus UL35 family DUF3454 PF11936.8 RUS72479.1 - 5.2 7.6 13.4 1.1e+03 0.1 13.4 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3454) PT PF04886.12 RUS72480.1 - 0.031 13.8 10.9 0.031 13.8 10.9 7.6 8 0 0 8 8 8 0 PT repeat DUF4524 PF15025.6 RUS72480.1 - 0.11 12.2 10.1 0.36 10.6 1.3 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4524) Endonuclease_5 PF04493.14 RUS72480.1 - 0.19 11.4 0.1 7 6.3 0.1 2.2 2 0 0 2 2 2 0 Endonuclease V DUF3969 PF13108.6 RUS72481.1 - 0.59 10.2 7.1 62 3.7 0.2 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF3969) Fasciclin PF02469.22 RUS72484.1 - 1.5e-05 25.2 0.1 1.9e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 RUS72485.1 - 0.00025 21.3 0.0 0.00032 20.9 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF4528 PF15031.6 RUS72486.1 - 2.8e-39 134.1 0.6 2.8e-39 134.1 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4528) TBCA PF02970.16 RUS72487.1 - 2.9e-31 107.6 11.4 3.6e-31 107.3 11.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF4355 PF14265.6 RUS72487.1 - 0.0031 17.8 7.7 0.0031 17.8 7.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4355) Fmp27_WPPW PF10359.9 RUS72487.1 - 0.036 12.9 4.5 0.038 12.8 4.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4972 PF16342.5 RUS72487.1 - 0.084 12.6 5.0 0.11 12.2 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) T2SSF PF00482.23 RUS72487.1 - 0.14 12.1 0.4 0.18 11.8 0.3 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F FapA PF03961.13 RUS72487.1 - 0.26 9.9 8.9 0.29 9.7 8.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 RUS72487.1 - 1.7 8.8 8.7 0.36 11.0 1.7 2.5 2 1 1 3 3 3 0 bZIP transcription factor ZapB PF06005.12 RUS72487.1 - 4.5 7.8 11.8 8 7.0 1.7 2.2 1 1 1 2 2 2 0 Cell division protein ZapB zf-C2HC_2 PF13913.6 RUS72488.1 - 3.9e-76 249.8 49.1 1.4e-11 44.0 0.8 8.2 8 0 0 8 8 8 8 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 RUS72488.1 - 2.6e-14 52.8 9.0 0.96 9.3 0.0 8.2 8 0 0 8 8 8 4 Rad50 zinc hook motif zf-C2H2 PF00096.26 RUS72488.1 - 4e-12 45.9 27.7 0.11 13.0 0.0 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS72488.1 - 1.4e-09 37.9 38.1 0.5 11.3 1.2 8.8 9 0 0 9 9 8 4 C2H2-type zinc finger DUF2318 PF10080.9 RUS72488.1 - 5e-08 33.0 20.9 0.6 10.3 0.0 8.0 8 0 0 8 8 8 2 Predicted membrane protein (DUF2318) c-SKI_SMAD_bind PF08782.10 RUS72488.1 - 4.7e-06 26.7 16.4 0.14 12.4 0.1 5.7 7 0 0 7 7 5 3 c-SKI Smad4 binding domain zinc_ribbon_4 PF13717.6 RUS72488.1 - 3.7e-05 23.6 12.6 20 5.2 0.0 7.6 7 0 0 7 7 7 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 RUS72488.1 - 6.1e-05 23.2 9.0 2.6 8.3 0.2 5.2 4 0 0 4 4 4 3 Ribosomal L32p protein family zf-RING_7 PF02591.15 RUS72488.1 - 9.4e-05 22.5 19.0 0.19 12.0 0.1 5.8 6 0 0 6 6 5 3 C4-type zinc ribbon domain Sgf11 PF08209.11 RUS72488.1 - 0.00016 21.1 35.8 0.37 10.4 0.3 8.2 8 0 0 8 8 8 2 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 RUS72488.1 - 0.00072 19.4 12.8 4.4 7.0 0.1 6.7 5 1 1 7 7 7 1 CpG binding protein zinc finger C terminal domain GcpE PF04551.14 RUS72488.1 - 0.0049 16.0 3.7 0.71 8.9 0.1 3.6 4 0 0 4 4 4 1 GcpE protein zf-HC5HC2H PF13771.6 RUS72488.1 - 0.0082 16.4 10.7 4.9 7.5 0.0 5.0 5 0 0 5 5 5 1 PHD-like zinc-binding domain DUF1178 PF06676.11 RUS72488.1 - 0.018 15.4 14.3 3.8 7.9 0.0 4.7 4 1 0 4 4 3 0 Protein of unknown function (DUF1178) zf_UBZ PF18439.1 RUS72488.1 - 0.042 13.4 18.0 5.7 6.6 0.0 7.1 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF3288 PF11691.8 RUS72488.1 - 0.082 13.0 0.0 33 4.6 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF3288) ROS_MUCR PF05443.11 RUS72488.1 - 0.086 12.9 0.7 34 4.5 0.0 4.0 4 1 0 4 4 4 0 ROS/MUCR transcriptional regulator protein zf-FPG_IleRS PF06827.14 RUS72488.1 - 0.12 12.2 13.0 4.5 7.2 0.3 4.8 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS HNH_5 PF14279.6 RUS72488.1 - 0.18 11.7 19.1 16 5.5 0.1 7.1 7 1 0 7 7 7 0 HNH endonuclease DUF2256 PF10013.9 RUS72488.1 - 0.45 10.7 30.8 19 5.5 0.1 8.3 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Toxin_24 PF08094.11 RUS72488.1 - 2 8.3 8.7 40 4.1 0.3 4.5 4 0 0 4 4 4 0 Conotoxin TVIIA/GS family zf-BED PF02892.15 RUS72488.1 - 4.4 7.4 16.6 49 4.1 0.1 5.9 7 0 0 7 7 6 0 BED zinc finger ADK_lid PF05191.14 RUS72488.1 - 6.1 6.9 22.5 4.2 7.4 0.1 7.0 7 2 1 8 8 8 0 Adenylate kinase, active site lid Pkinase PF00069.25 RUS72489.1 - 2.5e-70 236.9 0.0 4.9e-70 235.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72489.1 - 1.2e-46 159.2 0.0 3.4e-46 157.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase MIT PF04212.18 RUS72489.1 - 3.1e-34 116.8 6.6 1.3e-21 76.4 0.9 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Kdo PF06293.14 RUS72489.1 - 0.00021 20.7 0.8 0.00047 19.6 0.1 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS72489.1 - 0.012 15.2 1.4 0.02 14.5 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 RUS72489.1 - 0.036 13.6 3.4 0.39 10.3 0.0 3.5 3 2 2 5 5 5 0 Choline/ethanolamine kinase SDP_N PF12278.8 RUS72489.1 - 1.3 9.1 6.5 2.7 8.1 6.5 1.5 1 0 0 1 1 1 0 Sex determination protein N terminal ORC3_N PF07034.11 RUS72490.1 - 0.0081 15.3 4.4 0.01 15.0 4.4 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Dsh_C PF12316.8 RUS72490.1 - 3.7 7.9 5.0 3.5 8.0 4.2 1.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal eIF3_subunit PF08597.10 RUS72491.1 - 2.3e-54 184.8 24.9 2.6e-54 184.7 24.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.11 RUS72491.1 - 0.012 15.0 19.2 0.013 14.9 13.2 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TEX19 PF15553.6 RUS72491.1 - 1.3 9.0 4.0 2.8 7.9 4.0 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 FTCD_C PF04961.12 RUS72492.1 - 1.4e-31 109.7 0.2 1.6e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD_N PF07837.12 RUS72493.1 - 3.7e-72 241.8 0.0 5.8e-72 241.1 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 RUS72493.1 - 4.3e-66 221.4 0.5 6.2e-66 220.9 0.5 1.2 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 RUS72493.1 - 3.9e-22 78.9 0.0 7.8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Headcase PF16002.5 RUS72493.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Headcase protein Bromodomain PF00439.25 RUS72494.1 - 2e-06 27.7 0.0 6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 RUS72494.1 - 7.5e-06 26.3 0.5 7.5e-06 26.3 0.5 3.9 3 2 1 4 4 4 1 PWWP domain zf-MYND PF01753.18 RUS72494.1 - 0.014 15.5 22.3 0.014 15.5 22.3 2.9 2 1 0 2 2 2 0 MYND finger Mnd1 PF03962.15 RUS72494.1 - 0.94 9.8 3.5 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 Mnd1 HTH domain DUF4709 PF15821.5 RUS72495.1 - 5.9e-39 132.7 2.8 5.9e-39 132.7 2.8 4.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4709) UPF0242 PF06785.11 RUS72495.1 - 0.00057 20.1 23.2 0.00057 20.1 23.2 4.7 2 2 2 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 RUS72495.1 - 0.2 11.6 0.0 0.2 11.6 0.0 6.2 6 2 1 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 RUS72495.1 - 5.2 6.3 47.8 2.9 7.1 5.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Pox_M2 PF04887.12 RUS72496.1 - 0.069 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus M2 protein Thioredoxin_4 PF13462.6 RUS72497.1 - 0.023 14.9 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin RT_RNaseH_2 PF17919.1 RUS72498.1 - 9.6e-32 109.0 0.0 2.7e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS72498.1 - 1.8e-29 102.8 0.0 3.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 RUS72498.1 - 3.8e-27 94.6 0.0 8.8e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 RUS72498.1 - 1.2e-06 29.0 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS72498.1 - 0.001 19.6 0.0 0.0028 18.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Abhydrolase_1 PF00561.20 RUS72499.1 - 4.4e-09 36.4 0.0 5.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS72499.1 - 1.1e-08 36.0 0.5 1.3e-08 35.7 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS72499.1 - 1.5e-06 27.6 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 RUS72499.1 - 0.0037 16.0 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family His_Phos_2 PF00328.22 RUS72500.1 - 3.4e-27 95.8 0.0 1.2e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) NAP PF00956.18 RUS72500.1 - 4.1e-18 65.5 0.8 6.7e-18 64.8 0.8 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Aminotran_4 PF01063.19 RUS72502.1 - 0.11 12.3 0.0 0.59 9.9 0.0 2.1 1 1 1 2 2 2 0 Amino-transferase class IV Neur_chan_LBD PF02931.23 RUS72503.1 - 1.7e-26 93.1 0.0 2.4e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS72503.1 - 2.5e-13 50.6 0.3 5.7e-13 49.5 0.3 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Amino_oxidase PF01593.24 RUS72504.1 - 7.8e-10 38.6 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS72504.1 - 1e-09 38.5 0.7 2.5e-09 37.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 RUS72504.1 - 2.5e-08 34.1 0.0 6.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain zf-CW PF07496.15 RUS72504.1 - 1.4e-06 28.2 1.8 3.9e-06 26.8 1.8 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger DAO PF01266.24 RUS72504.1 - 3.6e-06 26.8 1.2 7.1e-06 25.8 1.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS72504.1 - 4.7e-06 26.0 1.0 1e-05 24.9 1.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 RUS72504.1 - 7.7e-06 25.4 0.8 1.3e-05 24.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RUS72504.1 - 1.8e-05 23.6 1.7 2.6e-05 23.1 1.7 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 RUS72504.1 - 3e-05 23.3 3.2 4.4e-05 22.7 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 RUS72504.1 - 3.8e-05 24.1 0.8 7.1e-05 23.3 0.8 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS72504.1 - 4.4e-05 22.9 0.0 7.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RUS72504.1 - 0.0004 19.9 1.2 0.00059 19.3 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RUS72504.1 - 0.0012 18.2 0.6 0.0021 17.4 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RUS72504.1 - 0.0054 16.0 0.1 0.0084 15.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 RUS72504.1 - 0.012 15.5 0.7 0.04 13.8 0.7 1.8 1 1 0 1 1 1 0 YjeF-related protein N-terminus GIDA PF01134.22 RUS72504.1 - 0.051 12.7 1.9 0.072 12.2 1.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 RUS72504.1 - 0.069 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RUS72504.1 - 0.086 11.9 0.7 0.13 11.3 0.7 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 RUS72504.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 RUS72504.1 - 0.22 9.9 0.5 0.33 9.3 0.5 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like IlvN PF07991.12 RUS72504.1 - 0.25 10.9 0.2 0.47 10.0 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pox_G7 PF05503.12 RUS72506.1 - 0.11 11.5 0.9 0.17 10.8 0.9 1.2 1 0 0 1 1 1 0 Poxvirus G7-like baeRF_family12 PF18856.1 RUS72506.1 - 0.36 11.4 5.9 0.4 11.3 4.5 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF5384 PF17358.2 RUS72506.1 - 1.2 9.2 16.7 8.4 6.4 16.7 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5384) Exo_endo_phos_2 PF14529.6 RUS72507.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LPMO_10 PF03067.15 RUS72508.1 - 6.9e-33 114.9 0.1 8.5e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-HIT PF04438.16 RUS72508.1 - 1 9.3 6.3 40 4.2 0.1 3.3 3 0 0 3 3 3 0 HIT zinc finger MFS_1 PF07690.16 RUS72509.1 - 3.2e-11 42.7 24.7 9.3e-11 41.2 24.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS72509.1 - 8.2e-05 21.6 3.9 8.2e-05 21.6 3.9 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2157 PF09925.9 RUS72509.1 - 0.0082 15.9 1.5 0.0082 15.9 1.5 3.3 3 2 0 3 3 3 1 Predicted membrane protein (DUF2157) GWT1 PF06423.12 RUS72509.1 - 0.21 11.7 3.7 3.2 7.9 0.4 3.1 2 1 0 2 2 2 0 GWT1 TMEM40 PF15817.5 RUS72509.1 - 1.6 8.5 5.5 14 5.5 3.8 2.5 2 0 0 2 2 2 0 Transmembrane protein 40 family DUF2663 PF10864.8 RUS72509.1 - 3.2 8.2 4.7 19 5.7 0.1 3.6 4 2 0 4 4 4 0 Protein of unknown function (DUF2663) TRIQK PF15168.6 RUS72509.1 - 4.2 7.3 5.6 2 8.4 0.1 2.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family LRR_8 PF13855.6 RUS72510.1 - 2.9e-48 161.5 16.8 1.1e-09 37.9 0.3 7.4 3 3 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 RUS72510.1 - 1e-24 86.1 16.1 0.00038 20.8 0.0 8.8 7 2 2 9 9 9 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS72510.1 - 4.9e-18 65.3 0.0 9.4e-07 28.8 0.0 3.9 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS72510.1 - 1.3e-13 49.4 10.2 0.62 10.8 0.1 10.6 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS72510.1 - 1e-05 25.1 1.6 0.29 10.6 0.0 3.9 1 1 3 5 5 5 3 Leucine-rich repeat HHH_5 PF14520.6 RUS72510.1 - 0.092 13.4 0.1 0.42 11.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain LRRNT PF01462.18 RUS72510.1 - 0.13 12.0 7.1 0.094 12.4 2.3 3.2 3 1 0 3 3 3 0 Leucine rich repeat N-terminal domain Suppressor_P21 PF11479.8 RUS72510.1 - 0.16 12.2 0.1 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 RNA silencing suppressor P21 C-terminal domain LRR_6 PF13516.6 RUS72510.1 - 0.57 10.4 31.2 2.2 8.5 0.0 10.0 12 0 0 12 12 12 0 Leucine Rich repeat MFS_1 PF07690.16 RUS72511.1 - 8e-08 31.6 17.6 1.3e-07 30.9 17.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HKR_ArcB_TM PF18415.1 RUS72512.1 - 0.019 15.7 0.3 22 5.9 0.0 2.9 1 1 3 4 4 4 0 Histidine kinase receptor ArcB trans-membrane domain DUF1943 PF09172.11 RUS72512.1 - 0.059 12.6 0.0 6.7 5.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1943) SCAB-PH PF17684.1 RUS72512.1 - 0.35 11.1 5.1 0.2 11.9 0.7 2.0 1 1 1 2 2 2 0 PH domain of plant-specific actin-binding protein EZH2_N PF18601.1 RUS72512.1 - 0.7 10.3 8.8 6.2 7.2 1.4 2.4 1 1 0 2 2 2 0 EZH2 N-terminal domain rpo30_N PF12410.8 RUS72512.1 - 1.5 8.7 6.4 20 5.1 1.0 2.5 1 1 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit TRAM1 PF08390.11 RUS72513.1 - 0.0048 16.5 0.0 22 4.8 0.0 3.5 3 1 0 3 3 3 3 TRAM1-like protein Acylphosphatase PF00708.18 RUS72514.1 - 1.3e-05 25.5 0.7 1.7 9.1 0.0 3.5 1 1 2 3 3 3 2 Acylphosphatase HKR_ArcB_TM PF18415.1 RUS72514.1 - 0.0027 18.5 0.1 25 5.7 0.0 3.8 1 1 1 4 4 4 1 Histidine kinase receptor ArcB trans-membrane domain Beta_helix PF13229.6 RUS72514.1 - 0.033 14.0 5.9 0.16 11.8 1.6 2.2 1 1 1 2 2 2 0 Right handed beta helix region DUF1943 PF09172.11 RUS72514.1 - 0.064 12.5 0.0 9.9 5.3 0.0 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) GH101_N PF17995.1 RUS72514.1 - 0.083 12.5 0.0 39 3.8 0.0 2.9 1 1 2 3 3 3 0 Endo-alpha-N-acetylgalactosaminidase N-terminal EZH2_N PF18601.1 RUS72514.1 - 1.2 9.5 24.9 0.44 10.9 1.2 3.8 3 1 0 4 4 4 0 EZH2 N-terminal domain rpo30_N PF12410.8 RUS72514.1 - 3.7 7.4 14.8 11 5.9 3.6 3.4 1 1 2 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit DUF5550 PF17704.1 RUS72515.1 - 6.9e-05 23.0 1.4 5.2 7.2 0.0 4.6 1 1 4 5 5 5 3 Family of unknown function (DUF5550) DUF2272 PF10030.9 RUS72515.1 - 0.04 13.7 1.0 1.9 8.2 0.0 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) PanZ PF12568.8 RUS72515.1 - 0.093 12.5 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ 5_nucleotid PF05761.14 RUS72516.1 - 1.9e-39 135.9 0.4 2.2e-39 135.6 0.4 1.1 1 0 0 1 1 1 1 5' nucleotidase family Herpes_gE PF02480.16 RUS72518.1 - 0.16 10.7 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Fibrinogen_C PF00147.18 RUS72519.1 - 1.9e-86 289.4 15.4 6.6e-53 179.8 6.1 2.1 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain MRP-L51 PF10244.9 RUS72519.1 - 0.22 11.8 2.5 3.7 7.8 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit Mod_r PF07200.13 RUS72520.1 - 6.5e-34 117.1 6.0 7.9e-34 116.9 6.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FliG_N PF14842.6 RUS72520.1 - 0.037 14.6 1.0 0.092 13.3 0.1 2.0 2 0 0 2 2 2 0 FliG N-terminal domain ZapB PF06005.12 RUS72520.1 - 0.048 14.1 7.8 0.059 13.8 4.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB KxDL PF10241.9 RUS72520.1 - 0.12 12.7 1.7 0.17 12.2 1.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein FlgN PF05130.12 RUS72520.1 - 0.35 11.4 7.5 0.2 12.2 4.9 1.7 1 1 0 1 1 1 0 FlgN protein RVT_1 PF00078.27 RUS72521.1 - 5.5e-05 22.8 0.0 0.00016 21.2 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF PF00209.18 RUS72522.1 - 3.1e-167 557.4 25.4 7.5e-167 556.2 25.4 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family FAM76 PF16046.5 RUS72524.1 - 0.016 14.6 14.0 0.019 14.3 14.0 1.0 1 0 0 1 1 1 0 FAM76 protein Lipase_GDSL_3 PF14606.6 RUS72524.1 - 0.017 15.3 1.5 0.027 14.6 1.4 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HMG_box_2 PF09011.10 RUS72524.1 - 1.3 9.6 5.1 6.6 7.4 0.6 2.5 2 0 0 2 2 2 0 HMG-box domain DUF4164 PF13747.6 RUS72524.1 - 2.3 8.6 12.8 2.1 8.7 7.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Exonuc_VII_L PF02601.15 RUS72524.1 - 2.6 7.5 11.1 3.6 7.1 11.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 RUS72524.1 - 2.8 5.8 8.4 3.2 5.6 8.4 1.0 1 0 0 1 1 1 0 Prominin E2F_CC-MB PF16421.5 RUS72524.1 - 5.1 7.5 9.2 0.38 11.1 2.0 2.5 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain ABC2_membrane_3 PF12698.7 RUS72525.1 - 1.9e-39 135.8 53.9 2.4e-25 89.4 17.9 4.4 3 1 1 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 RUS72525.1 - 2.6e-37 128.4 0.0 2.9e-24 86.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS72525.1 - 4.6e-18 66.1 0.0 2.8e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 RUS72525.1 - 7.1 5.8 41.9 0.42 9.8 16.8 3.9 2 1 2 4 4 4 0 ABC-2 family transporter protein pP_pnuc_2 PF18166.1 RUS72526.1 - 0.12 12.4 0.6 0.33 11.0 0.3 1.8 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease XPC-binding PF09280.11 RUS72526.1 - 0.3 10.9 2.2 6.6 6.6 0.1 3.9 3 0 0 3 3 3 0 XPC-binding domain TMEM154 PF15102.6 RUS72529.1 - 3.2e-06 27.1 0.9 5.8e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 RUS72529.1 - 0.0075 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Podoplanin PF05808.11 RUS72529.1 - 0.0086 16.2 0.7 0.018 15.2 0.7 1.5 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.16 RUS72529.1 - 0.021 13.6 0.1 0.034 12.9 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2140 PF09911.9 RUS72529.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Orf78 PF06024.12 RUS72529.1 - 0.033 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 RUS72529.1 - 0.061 14.2 1.3 0.73 10.8 0.9 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 RUS72529.1 - 0.15 11.9 1.7 0.29 10.9 1.7 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor zf-CCHC PF00098.23 RUS72530.1 - 8.1e-06 25.7 3.4 1.6e-05 24.8 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS72530.1 - 0.00049 19.9 3.3 0.00086 19.1 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS72530.1 - 0.0064 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS72530.1 - 0.033 13.9 1.7 0.079 12.7 1.7 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SpoVR PF04293.13 RUS72531.1 - 0.041 12.6 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein rve PF00665.26 RUS72531.1 - 0.091 13.0 0.0 0.72 10.1 0.0 2.2 1 1 0 1 1 1 0 Integrase core domain Cadherin PF00028.17 RUS72532.1 - 8.4e-96 314.6 0.1 2.7e-19 69.4 0.0 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS72532.1 - 2e-10 40.4 0.0 1.6e-07 31.0 0.1 3.8 3 1 0 3 3 3 1 Cadherin-like Cadherin_pro PF08758.11 RUS72532.1 - 2.5e-05 24.3 0.0 1.1 9.5 0.0 3.8 3 1 0 3 3 3 2 Cadherin prodomain like TMEM154 PF15102.6 RUS72532.1 - 0.024 14.6 0.0 0.085 12.8 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.12 RUS72532.1 - 0.094 12.5 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Kinesin PF00225.23 RUS72535.1 - 2.1e-109 365.5 0.0 2.1e-109 365.5 0.0 3.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RUS72535.1 - 1.5e-20 73.7 0.0 1.5e-20 73.7 0.0 3.5 4 1 0 4 4 4 1 Microtubule binding Asp4 PF16996.5 RUS72535.1 - 9.9 6.0 6.3 62 3.5 0.6 3.7 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 zf-H2C2_2 PF13465.6 RUS72536.1 - 2.5e-66 217.3 152.3 4.3e-07 30.1 1.4 20.1 20 1 0 20 20 20 15 Zinc-finger double domain zf-C2H2 PF00096.26 RUS72536.1 - 2.3e-64 210.4 157.0 7.8e-05 22.9 1.2 19.2 19 0 0 19 19 19 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS72536.1 - 3.8e-58 189.1 150.1 0.0002 22.0 3.1 19.2 19 0 0 19 19 19 19 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS72536.1 - 1.1e-20 73.3 87.3 0.044 14.1 1.3 16.7 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS72536.1 - 3.8e-16 58.9 122.8 0.02 15.3 0.3 17.4 19 0 0 19 19 18 13 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS72536.1 - 2e-15 56.3 136.4 0.00039 20.3 4.0 18.9 20 1 0 20 20 19 12 C2H2-type zinc finger zf-Di19 PF05605.12 RUS72536.1 - 7.5e-07 29.3 109.6 4e-05 23.8 2.0 11.6 5 4 7 12 12 11 6 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS72536.1 - 2.4e-06 28.3 73.2 1.3 9.7 6.1 12.1 2 2 8 10 10 10 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 RUS72536.1 - 7.7e-05 22.4 23.2 0.00044 20.0 5.6 15.5 17 2 0 17 17 16 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS72536.1 - 0.00021 21.0 0.8 0.00021 21.0 0.8 16.6 18 1 0 18 18 17 4 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RUS72536.1 - 0.0045 17.1 0.7 0.0045 17.1 0.7 13.8 9 4 6 15 15 13 3 Zinc ribbon domain zf-C2H2_2 PF12756.7 RUS72536.1 - 0.012 16.0 110.1 2.5 8.5 1.0 16.2 1 1 10 12 12 12 0 C2H2 type zinc-finger (2 copies) NosL PF05573.12 RUS72536.1 - 0.015 15.6 0.1 0.093 13.1 0.1 2.4 1 0 0 1 1 1 0 NosL Zn-C2H2_12 PF18112.1 RUS72536.1 - 0.018 15.5 0.7 0.17 12.4 0.2 13.7 14 0 0 14 14 13 0 Autophagy receptor zinc finger-C2H2 domain HypA PF01155.19 RUS72536.1 - 0.06 13.4 0.2 0.06 13.4 0.2 8.9 1 1 6 7 7 7 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 RUS72536.1 - 0.1 13.3 42.4 0.22 12.2 0.7 10.2 8 4 1 9 9 9 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.13 RUS72536.1 - 4 7.6 84.4 0.09 12.8 4.6 10.9 2 2 11 13 13 13 0 Transcription elongation factor Elf1 like IMCp PF12314.8 RUS72537.1 - 0.044 14.1 11.6 0.089 13.1 11.6 1.5 1 0 0 1 1 1 0 Inner membrane complex protein MULE PF10551.9 RUS72538.1 - 1.3e-11 44.7 0.4 1.5e-10 41.3 0.1 2.4 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_1_7 PF13843.6 RUS72539.1 - 3.6e-67 227.2 0.8 5.3e-67 226.6 0.8 1.3 1 0 0 1 1 1 1 Transposase IS4 HTH_psq PF05225.16 RUS72539.1 - 3.3e-06 26.7 0.0 7.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 RUS72539.1 - 0.00062 19.7 0.1 0.0028 17.6 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_Tnp_1 PF01609.21 RUS72539.1 - 0.0035 17.0 2.1 0.0091 15.7 2.1 1.7 1 1 0 1 1 1 1 Transposase DDE domain Tnp_zf-ribbon_2 PF13842.6 RUS72539.1 - 0.019 15.7 0.8 0.04 14.7 0.8 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF4185 PF13810.6 RUS72539.1 - 0.056 12.7 0.2 0.097 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) RNase_H PF00075.24 RUS72540.1 - 3.7e-35 121.2 0.1 5e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS72540.1 - 0.00019 21.3 0.0 0.00026 20.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase-like ANF_receptor PF01094.28 RUS72541.1 - 1.4e-28 100.0 0.0 1.9e-24 86.4 0.0 2.0 1 1 1 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS72541.1 - 7.1e-08 32.5 0.0 8.7e-07 28.9 0.0 1.9 1 1 1 2 2 2 1 Periplasmic binding protein FAM60A PF15396.6 RUS72543.1 - 0.0021 18.1 4.7 0.0027 17.8 4.7 1.1 1 0 0 1 1 1 1 Protein Family FAM60A NPR3 PF03666.13 RUS72543.1 - 0.0046 15.8 6.0 0.0053 15.6 6.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS72543.1 - 0.025 12.9 8.8 0.029 12.7 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RUS72543.1 - 0.035 12.9 6.7 0.036 12.9 6.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Gti1_Pac2 PF09729.9 RUS72543.1 - 0.035 14.2 6.1 0.046 13.8 6.1 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family NOA36 PF06524.12 RUS72543.1 - 0.041 13.2 19.9 0.096 12.0 16.6 2.0 2 0 0 2 2 2 0 NOA36 protein DUF4746 PF15928.5 RUS72543.1 - 0.047 13.1 5.7 0.058 12.8 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Connexin PF00029.19 RUS72543.1 - 0.06 13.1 0.8 0.086 12.6 0.8 1.5 1 0 0 1 1 1 0 Connexin RRN3 PF05327.11 RUS72543.1 - 0.1 11.2 3.6 0.11 11.1 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tim54 PF11711.8 RUS72543.1 - 0.1 11.4 5.5 0.13 11.1 5.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 RUS72543.1 - 0.12 12.8 5.4 0.18 12.2 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 RUS72543.1 - 0.15 10.3 11.7 0.17 10.1 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 RUS72543.1 - 0.32 9.9 8.8 0.39 9.7 8.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Menin PF05053.13 RUS72543.1 - 0.74 8.1 8.6 0.9 7.8 8.6 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 RUS72543.1 - 1.2 7.8 12.2 1.9 7.2 12.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 RUS72543.1 - 2.1 7.7 8.9 3.6 6.9 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Mem_trans PF03547.18 RUS72543.1 - 2.5 6.4 3.9 3.3 6.0 3.9 1.2 1 0 0 1 1 1 0 Membrane transport protein ALMT PF11744.8 RUS72543.1 - 2.8 6.7 7.4 3.6 6.3 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 RUS72543.1 - 3.4 6.8 7.2 5 6.2 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.19 RUS72543.1 - 8.5 5.2 8.2 11 4.8 8.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3450 PF11932.8 RUS72543.1 - 8.5 5.6 10.1 13 5.0 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glyco_hydro_18 PF00704.28 RUS72544.1 - 7.9e-28 98.1 1.0 1.3e-27 97.3 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GspL_C PF12693.7 RUS72544.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 GspL periplasmic domain VHP PF02209.19 RUS72544.1 - 2 8.6 5.8 0.97 9.6 1.1 2.4 2 0 0 2 2 2 0 Villin headpiece domain Patched PF02460.18 RUS72545.1 - 2.2e-12 45.9 0.0 2.5e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Patched family ALS2CR8 PF15299.6 RUS72545.1 - 0.031 14.2 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Peptidase_M28 PF04389.17 RUS72546.1 - 8.6e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.17 RUS72547.1 - 4.7e-21 75.4 0.0 6.2e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 AMPK1_CBM PF16561.5 RUS72548.1 - 3.9e-27 94.3 0.2 5.9e-27 93.7 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RVT_1 PF00078.27 RUS72549.1 - 5.2e-07 29.4 0.0 8.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDC45 PF02724.14 RUS72549.1 - 0.0027 16.1 10.8 0.0035 15.7 10.8 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 RUS72549.1 - 0.0042 17.2 12.6 0.0052 16.9 12.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Mpp10 PF04006.12 RUS72549.1 - 0.0042 15.6 9.2 0.0048 15.4 9.2 1.1 1 0 0 1 1 1 1 Mpp10 protein Pox_ser-thr_kin PF05445.11 RUS72549.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nop14 PF04147.12 RUS72549.1 - 0.85 7.8 23.0 1.1 7.4 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS72549.1 - 0.97 7.7 5.3 1.1 7.4 5.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 RUS72549.1 - 1.3 8.4 21.1 1.7 8.0 21.1 1.1 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 RUS72549.1 - 3.5 7.3 9.9 7.9 6.2 9.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 RUS72549.1 - 4.7 5.2 37.8 6.6 4.7 37.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 RUS72549.1 - 5.2 5.0 9.7 8.5 4.3 9.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Slu7 PF11708.8 RUS72549.1 - 8.2 6.1 15.0 23 4.6 15.0 1.7 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor FTHFS PF01268.19 RUS72550.1 - 6.5e-259 859.8 0.1 8.7e-259 859.4 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 RUS72550.1 - 2.5e-67 225.1 1.4 2.7e-67 225.1 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RUS72550.1 - 2.6e-31 108.3 1.4 5.6e-31 107.2 1.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain UPF0052 PF01933.18 RUS72550.1 - 0.036 13.3 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 MBOAT PF03062.19 RUS72551.1 - 1.2e-24 87.3 7.8 2.7e-24 86.2 7.8 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NPCC PF08058.11 RUS72551.1 - 0.14 12.2 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore complex component DUF5313 PF17240.2 RUS72551.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5313) DUF3464 PF11947.8 RUS72551.1 - 0.75 9.5 6.2 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 PRELI PF04707.14 RUS72552.1 - 1.1e-28 100.1 0.1 1.2e-28 99.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family DUF4187 PF13821.6 RUS72553.1 - 3.3e-21 74.8 0.4 9.9e-21 73.3 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 RUS72553.1 - 3.5e-15 55.6 4.2 4.4e-15 55.3 2.7 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RUS72553.1 - 9.6e-08 32.0 0.5 2.7e-07 30.6 0.5 1.9 1 0 0 1 1 1 1 G-patch domain PV-1 PF06637.11 RUS72553.1 - 0.00068 18.6 1.4 0.014 14.2 0.2 2.1 2 0 0 2 2 2 2 PV-1 protein (PLVAP) DUF1571 PF07608.11 RUS72553.1 - 0.11 11.9 3.4 0.049 13.1 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) Thiolase_C PF02803.18 RUS72554.1 - 3.9e-12 45.9 0.5 7.9e-12 44.9 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 RUS72554.1 - 0.0054 16.1 0.6 0.15 11.4 0.5 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS72554.1 - 0.014 15.4 0.1 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 RUS72555.1 - 1.6e-17 63.8 0.0 6.4e-16 58.5 0.0 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS72555.1 - 9e-15 54.4 0.3 6.4e-14 51.7 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RUS72555.1 - 2.9e-06 27.1 0.6 0.0016 18.0 0.1 3.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS72555.1 - 0.00024 21.1 0.5 0.15 12.0 0.0 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 RUS72555.1 - 0.00061 18.6 0.7 0.0021 16.8 0.1 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 RUS72555.1 - 0.00097 18.9 0.5 0.0083 16.0 0.1 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DSBA PF01323.20 RUS72555.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain MMADHC PF10229.9 RUS72556.1 - 4.1e-10 39.9 0.0 5.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein EF-hand_7 PF13499.6 RUS72558.1 - 1.1e-09 38.5 0.0 3.9e-06 27.2 0.0 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS72558.1 - 2.2e-09 36.5 0.0 6.4e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RUS72558.1 - 8.3e-09 34.4 0.0 0.00065 19.1 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 RUS72558.1 - 0.00072 18.9 0.0 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RUS72558.1 - 0.0011 18.7 0.4 0.075 12.9 0.0 2.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 RUS72558.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 RUS72558.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 Dockerin type I domain Glyco_transf_21 PF13506.6 RUS72560.1 - 5e-36 123.8 0.0 6.6e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RUS72560.1 - 1.6e-09 38.0 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PP1_bind PF15276.6 RUS72561.1 - 1.1e-13 51.3 8.7 1.1e-13 51.3 8.7 10.3 6 1 1 8 8 8 1 Protein phosphatase 1 binding FHA PF00498.26 RUS72561.1 - 5e-08 33.2 0.2 8.6e-08 32.4 0.2 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS72561.1 - 0.0087 16.4 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 RUS72561.1 - 0.026 14.7 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 FHA domain GRAM PF02893.20 RUS72565.1 - 2.7e-16 59.5 0.1 4.6e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 GRAM domain Actin PF00022.19 RUS72566.1 - 9.9e-130 432.8 0.0 7.1e-129 430.0 0.0 1.8 1 1 0 1 1 1 1 Actin Peroxin-22 PF12827.7 RUS72566.1 - 0.076 12.9 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family MreB_Mbl PF06723.13 RUS72566.1 - 0.14 10.9 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Ras PF00071.22 RUS72568.1 - 2.8e-41 140.8 0.1 3.3e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72568.1 - 3.8e-27 94.9 0.0 6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72568.1 - 8e-10 38.4 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS72568.1 - 9.7e-05 21.8 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS72568.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS72568.1 - 0.032 14.1 0.0 9.5 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Motilin_ghrelin PF04644.12 RUS72568.1 - 0.091 12.6 0.7 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Motilin/ghrelin Aldolase_II PF00596.21 RUS72569.1 - 1.5e-41 142.4 0.6 2.6e-41 141.6 0.6 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AbrB-like PF14250.6 RUS72570.1 - 0.16 12.1 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 AbrB-like transcriptional regulator Presenilin PF01080.17 RUS72570.1 - 5.8 5.6 4.8 8 5.1 4.8 1.3 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 RUS72571.1 - 0.0075 17.1 1.2 0.024 15.5 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 DUF4062 PF13271.6 RUS72572.1 - 0.036 14.4 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Delta_lysin PF05372.11 RUS72572.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family AMP-binding_C PF13193.6 RUS72573.1 - 6.9e-06 27.0 0.0 1.2e-05 26.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain HLH PF00010.26 RUS72576.1 - 1.5e-11 44.1 1.1 2e-11 43.7 1.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Arteri_Gl PF00951.18 RUS72576.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Cu2_monoox_C PF03712.15 RUS72577.1 - 1.6e-23 82.9 0.0 3.5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RUS72577.1 - 2.3e-23 82.8 0.0 4.5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Bac_rhamnosid_N PF08531.10 RUS72577.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain REV1_C PF16727.5 RUS72578.1 - 1.1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 RUS72578.1 - 0.39 10.2 2.4 9.3 5.9 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin binding region PPS_PS PF02006.16 RUS72579.1 - 1.9 8.0 26.8 27 4.3 0.2 8.9 1 1 9 10 10 10 0 Phosphopantothenate/pantothenate synthetase BPS PF08947.10 RUS72580.1 - 2e-11 43.5 43.4 8.5 6.3 0.2 12.0 9 2 3 12 12 12 11 BPS (Between PH and SH2) AChE_tetra PF08674.10 RUS72580.1 - 2.1e-09 36.9 31.1 2.6 7.8 0.1 10.6 1 1 9 11 11 11 10 Acetylcholinesterase tetramerisation domain Peptidase_M15_2 PF05951.13 RUS72580.1 - 7e-05 22.5 9.5 14 5.3 0.2 5.5 1 1 7 8 8 8 4 Bacterial protein of unknown function (DUF882) DUF4767 PF15983.5 RUS72580.1 - 0.00048 20.4 16.9 2.2 8.5 0.0 6.2 1 1 6 9 9 9 3 Domain of unknown function (DUF4767) DUF1601 PF07671.11 RUS72580.1 - 0.76 9.7 10.2 41 4.1 0.1 6.8 12 0 0 12 12 12 0 Protein of unknown function (DUF1601) 7tm_1 PF00001.21 RUS72581.1 - 8.2e-05 22.1 2.3 0.00012 21.5 2.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS72582.1 - 1.5e-44 152.4 12.5 1.8e-44 152.0 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS72582.1 - 2.4e-09 37.4 7.1 2.4e-09 37.4 7.1 1.9 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 RUS72582.1 - 0.00018 20.9 7.4 0.001 18.4 4.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 RUS72582.1 - 0.0099 15.6 13.2 0.0099 15.6 13.2 1.6 2 0 0 2 2 2 1 Srg family chemoreceptor Git3 PF11710.8 RUS72582.1 - 0.026 14.3 9.1 0.05 13.4 9.1 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TAS2R PF05296.13 RUS72582.1 - 0.45 9.6 11.2 2.1 7.4 0.2 2.6 2 1 0 2 2 2 0 Taste receptor protein (TAS2R) Peptidase_C1 PF00112.23 RUS72583.1 - 2.4e-59 201.0 10.7 3.2e-59 200.6 10.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RUS72583.1 - 2.7e-06 27.2 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS72583.1 - 3.8 6.2 5.5 6.7 5.4 0.7 2.2 2 1 0 2 2 2 0 Peptidase C1-like family RNA_pol_Rpc4 PF05132.14 RUS72584.1 - 0.001 19.5 16.1 0.0016 18.9 16.1 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 CDC45 PF02724.14 RUS72584.1 - 0.0017 16.7 22.5 0.0021 16.5 22.5 1.0 1 0 0 1 1 1 1 CDC45-like protein SRP-alpha_N PF04086.13 RUS72584.1 - 0.0047 16.9 28.5 0.0076 16.2 28.5 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.17 RUS72584.1 - 0.054 13.6 11.3 0.07 13.3 11.3 1.2 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 RUS72584.1 - 0.063 13.0 18.8 0.081 12.7 18.8 1.1 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.12 RUS72584.1 - 0.072 12.5 33.1 0.11 11.9 33.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SAPS PF04499.15 RUS72584.1 - 0.13 11.1 8.2 0.14 10.9 8.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 RUS72584.1 - 0.15 12.3 26.8 0.24 11.6 26.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2052 PF09747.9 RUS72584.1 - 0.35 11.0 18.3 0.47 10.6 18.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) YL1 PF05764.13 RUS72584.1 - 0.36 10.9 43.7 0.52 10.4 43.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Vfa1 PF08432.10 RUS72584.1 - 0.41 11.0 38.7 0.62 10.4 38.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SLC12 PF03522.15 RUS72584.1 - 0.62 9.0 21.5 0.75 8.7 21.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PTPRCAP PF15713.5 RUS72584.1 - 0.71 10.2 12.3 1.2 9.4 12.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.12 RUS72584.1 - 0.73 8.7 10.1 0.85 8.5 10.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DAG_kinase_N PF14513.6 RUS72584.1 - 0.75 10.0 17.1 0.99 9.6 17.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RR_TM4-6 PF06459.12 RUS72584.1 - 0.77 9.5 29.8 1 9.1 29.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 RUS72584.1 - 0.9 8.6 16.5 1.2 8.2 16.5 1.1 1 0 0 1 1 1 0 SprA-related family XRN_M PF17846.1 RUS72584.1 - 1.5 7.7 13.9 1.8 7.5 13.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Connexin PF00029.19 RUS72584.1 - 1.6 8.4 24.5 2.7 7.7 24.5 1.4 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 RUS72584.1 - 2.1 8.3 13.8 2.9 7.9 13.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 RUS72584.1 - 2.3 6.9 20.0 2.8 6.6 20.0 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 RUS72584.1 - 2.4 7.1 21.5 2.8 6.8 21.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 RUS72584.1 - 4.5 6.1 11.8 5.4 5.8 11.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4776 PF16003.5 RUS72584.1 - 5.4 5.9 35.0 7.5 5.4 35.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) VIR_N PF15912.5 RUS72584.1 - 5.9 6.4 13.3 8.1 6.0 13.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal eIF3_subunit PF08597.10 RUS72584.1 - 6.2 6.7 48.7 10 5.9 48.7 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2828 PF11443.8 RUS72584.1 - 6.4 4.7 29.6 8.8 4.3 29.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SpoIIP PF07454.11 RUS72584.1 - 7.6 5.9 25.0 10 5.5 25.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5427 PF10310.9 RUS72584.1 - 9.7 5.0 23.5 12 4.7 23.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ALMT PF11744.8 RUS72584.1 - 10 4.9 17.5 12 4.6 17.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spt20 PF12090.8 RUS72584.1 - 10 5.7 18.9 15 5.1 18.9 1.2 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 RUS72585.1 - 8.9e-19 67.1 0.1 1.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS72585.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_3 PF13927.6 RUS72586.1 - 1.5e-207 672.8 108.9 8.8e-12 45.5 0.3 28.7 28 1 0 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 RUS72586.1 - 8.6e-195 631.6 93.2 4.8e-10 39.6 0.3 27.4 27 1 0 27 27 27 26 Immunoglobulin domain I-set PF07679.16 RUS72586.1 - 9.8e-172 557.6 39.4 5.8e-09 35.9 0.0 33.8 29 9 0 29 29 29 26 Immunoglobulin I-set domain ig PF00047.25 RUS72586.1 - 1.1e-101 333.2 91.5 7.8e-09 35.6 0.2 31.7 26 8 2 28 28 28 23 Immunoglobulin domain Ig_4 PF16680.5 RUS72586.1 - 5.7e-53 177.1 41.6 0.024 14.9 0.0 23.1 23 0 0 23 23 23 14 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 RUS72586.1 - 1.9e-50 169.6 87.3 0.00091 19.4 0.1 34.3 27 10 11 38 38 38 11 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS72586.1 - 8.4e-38 127.7 0.0 0.095 12.3 0.0 21.1 23 0 0 23 23 23 5 Immunoglobulin domain Izumo-Ig PF16706.5 RUS72586.1 - 1.4e-18 66.7 10.7 3.1 7.9 0.0 19.2 22 1 1 23 23 23 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 RUS72586.1 - 8.7e-12 45.2 0.2 2.8e-10 40.4 0.0 3.0 2 0 0 2 2 2 1 Fibronectin type III domain Ig_C17orf99 PF17736.1 RUS72586.1 - 8.9e-08 32.1 42.1 1.7 8.7 0.1 17.8 25 1 0 25 25 19 2 C17orf99 Ig domain FAM176 PF14851.6 RUS72586.1 - 0.00049 19.8 1.5 0.0012 18.5 1.5 1.6 1 0 0 1 1 1 1 FAM176 family Putative_PNPOx PF01243.20 RUS72586.1 - 0.0028 17.8 0.0 55 4.0 0.0 5.4 5 0 0 5 5 5 0 Pyridoxamine 5'-phosphate oxidase Receptor_2B4 PF11465.8 RUS72586.1 - 0.01 16.0 3.0 52 4.1 0.0 6.7 8 0 0 8 8 5 0 Natural killer cell receptor 2B4 Adhes-Ig_like PF09085.10 RUS72586.1 - 0.01 15.9 0.4 0.12 12.6 0.2 2.8 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like TRAP_alpha PF03896.16 RUS72586.1 - 0.032 13.4 8.8 0.054 12.7 8.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RUS72586.1 - 0.093 10.8 36.0 0.13 10.3 36.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TMEM154 PF15102.6 RUS72586.1 - 0.29 11.0 1.2 0.59 10.0 1.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mpp10 PF04006.12 RUS72586.1 - 8 4.8 17.1 11 4.3 17.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Pkinase PF00069.25 RUS72587.1 - 7.2e-52 176.3 0.0 1.3e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72587.1 - 6.6e-23 81.3 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 RUS72587.1 - 0.024 13.6 2.1 0.039 12.9 2.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C3 PF00548.20 RUS72587.1 - 0.07 13.0 0.6 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) Choline_kinase PF01633.20 RUS72587.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase Plectin PF00681.20 RUS72590.1 - 1.3e-17 63.3 0.0 0.022 14.6 0.0 6.2 5 1 1 6 6 6 4 Plectin repeat SH3_10 PF17902.1 RUS72590.1 - 3.5e-16 59.0 0.0 1.8e-15 56.7 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_1 PF00018.28 RUS72590.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS72590.1 - 0.02 14.7 0.1 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain Vpu PF00558.19 RUS72590.1 - 0.034 13.9 0.1 0.13 12.0 0.1 2.0 1 0 0 1 1 1 0 Vpu protein SH3_2 PF07653.17 RUS72590.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Glypican PF01153.19 RUS72591.1 - 0.0015 17.5 0.0 0.0093 14.8 0.0 1.9 2 0 0 2 2 2 1 Glypican Glypican PF01153.19 RUS72592.1 - 1.5e-39 136.3 0.5 1.5e-39 136.3 0.5 2.0 1 1 1 2 2 1 1 Glypican Fz PF01392.22 RUS72592.1 - 0.00067 20.3 0.6 0.0013 19.4 0.6 1.4 1 0 0 1 1 1 1 Fz domain TFIIA PF03153.13 RUS72592.1 - 0.0032 17.5 14.7 0.0041 17.2 14.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RUS72592.1 - 0.0064 15.9 14.7 0.0082 15.5 14.7 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 RUS72592.1 - 0.0068 15.9 22.8 0.0087 15.5 22.8 1.1 1 0 0 1 1 1 1 SDA1 Vfa1 PF08432.10 RUS72592.1 - 0.054 13.8 5.9 0.088 13.1 5.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CNDH2_C PF16858.5 RUS72592.1 - 0.32 10.8 8.1 0.43 10.4 8.1 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF913 PF06025.12 RUS72592.1 - 0.33 9.9 1.4 0.52 9.2 1.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 RUS72592.1 - 0.49 9.8 7.6 0.68 9.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 RUS72592.1 - 2.6 6.7 7.5 4.2 6.1 7.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 RUS72592.1 - 5.3 5.0 39.6 18 3.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase phi Glypican PF01153.19 RUS72593.1 - 5.4e-13 48.6 0.0 5.4e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Glypican Pkinase PF00069.25 RUS72594.1 - 6e-66 222.5 0.0 8.6e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72594.1 - 1.1e-28 100.2 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS72594.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS72594.1 - 0.00065 19.1 0.0 0.0016 17.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS72594.1 - 0.0092 14.8 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS72594.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTD_bind PF04818.13 RUS72595.1 - 7.9e-18 65.0 0.8 3.2e-17 63.1 0.8 2.2 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 RUS72595.1 - 2.4e-16 59.4 0.5 4.6e-16 58.5 0.5 1.5 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 RUS72595.1 - 9.8e-13 47.8 2.0 2.4e-12 46.5 2.0 1.7 1 0 0 1 1 1 1 G-patch domain Stevor PF17410.2 RUS72595.1 - 0.014 14.9 2.9 0.075 12.6 0.8 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame G-patch_2 PF12656.7 RUS72595.1 - 0.093 12.8 1.1 0.3 11.2 1.1 1.9 1 0 0 1 1 1 0 G-patch domain DUF3781 PF12636.7 RUS72595.1 - 1.8 8.5 4.3 0.75 9.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Baculo_PEP_C PF04513.12 RUS72595.1 - 5.5 7.0 21.8 3.7 7.6 2.9 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3522 PF12036.8 RUS72596.1 - 1.5e-35 123.2 12.0 2e-35 122.8 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.11 RUS72596.1 - 0.11 12.4 12.5 0.086 12.7 4.5 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4516 PF14990.6 RUS72596.1 - 1.6 8.5 3.8 0.41 10.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) DUF4131 PF13567.6 RUS72596.1 - 4.3 6.9 5.7 1.4 8.6 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 7tm_1 PF00001.21 RUS72597.1 - 1e-06 28.3 6.8 1e-06 28.3 6.8 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72597.1 - 5.8e-06 26.1 27.2 0.0012 18.5 16.7 3.1 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx p450 PF00067.22 RUS72598.1 - 3.7e-97 326.0 0.0 4.2e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 RUS72599.1 - 2.5e-19 69.4 41.8 6.6e-17 61.5 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS72599.1 - 0.00026 20.0 3.8 0.00026 20.0 3.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter ubiquitin PF00240.23 RUS72600.1 - 6e-07 29.1 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Arm PF00514.23 RUS72600.1 - 0.0012 18.8 0.1 0.039 14.0 0.0 2.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat BMC PF00936.19 RUS72600.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 BMC domain ELYS-bb PF16687.5 RUS72601.1 - 1.3e-57 195.6 2.3 1e-55 189.3 2.3 2.0 1 1 0 1 1 1 1 beta-propeller of ELYS nucleoporin ELYS PF13934.6 RUS72602.1 - 4.9e-32 111.7 0.1 4.9e-32 111.7 0.1 2.6 3 1 0 3 3 3 1 Nuclear pore complex assembly Anoctamin PF04547.12 RUS72604.1 - 0.0009 18.2 2.1 0.0011 17.9 2.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Apis_Csd PF11671.8 RUS72604.1 - 0.0046 17.0 1.5 0.0084 16.1 1.5 1.4 1 0 0 1 1 1 1 Complementary sex determiner protein DUF2956 PF11169.8 RUS72604.1 - 0.01 16.0 1.6 0.016 15.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Vma12 PF11712.8 RUS72604.1 - 0.011 15.8 1.0 0.014 15.4 0.7 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Atrophin-1 PF03154.15 RUS72604.1 - 0.037 12.3 14.1 0.042 12.1 14.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family NPR3 PF03666.13 RUS72604.1 - 0.32 9.7 2.9 0.38 9.5 2.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS72604.1 - 0.43 8.8 6.0 0.48 8.7 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Orf78 PF06024.12 RUS72604.1 - 0.46 10.8 0.0 0.46 10.8 0.0 2.5 2 1 1 3 3 2 0 Orf78 (ac78) Afi1 PF07792.12 RUS72604.1 - 0.47 10.9 3.5 0.63 10.5 3.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Phtf-FEM1B_bdg PF12129.8 RUS72604.1 - 0.99 9.2 7.1 1.4 8.8 7.1 1.2 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor LptF_LptG PF03739.14 RUS72604.1 - 2.9 6.7 4.2 3 6.6 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG 7TM_GPCR_Srw PF10324.9 RUS72605.1 - 1.7e-29 103.1 14.4 2.1e-29 102.9 14.4 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS72605.1 - 3.2e-12 46.3 15.2 4.5e-12 45.8 15.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sm_multidrug_ex PF06695.11 RUS72605.1 - 0.01 16.5 1.1 0.01 16.5 1.1 3.0 3 0 0 3 3 3 0 Putative small multi-drug export protein 7TM_GPCR_Srw PF10324.9 RUS72606.1 - 2.2e-31 109.4 15.0 2.6e-31 109.1 15.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS72606.1 - 6.3e-12 45.4 15.2 9e-12 44.9 15.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS72606.1 - 0.0042 16.5 12.9 0.12 11.7 3.2 2.6 1 1 2 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx Sm_multidrug_ex PF06695.11 RUS72606.1 - 0.032 14.9 2.0 0.032 14.9 2.0 3.1 3 1 1 4 4 4 0 Putative small multi-drug export protein FmiP_Thoc5 PF09766.9 RUS72607.1 - 1.4e-125 419.4 9.9 1.9e-125 419.0 9.9 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Cytochrom_CIII PF02085.16 RUS72607.1 - 0.2 12.0 4.4 0.48 10.8 4.4 1.6 1 0 0 1 1 1 0 Class III cytochrome C family DUF948 PF06103.11 RUS72607.1 - 0.22 11.8 1.6 9.8 6.5 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 RUS72607.1 - 1.9 8.9 6.8 1.6 9.1 0.5 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 RUS72607.1 - 2 8.5 5.7 1.6 8.7 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CPSF100_C PF13299.6 RUS72607.1 - 10 6.3 7.9 14 5.8 0.5 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM76 PF16046.5 RUS72609.1 - 0.00095 18.6 1.7 0.0012 18.3 1.7 1.1 1 0 0 1 1 1 1 FAM76 protein DUF4746 PF15928.5 RUS72609.1 - 0.054 12.9 3.0 0.071 12.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 RUS72609.1 - 0.35 10.0 0.4 0.35 10.0 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 RUS72609.1 - 0.39 8.6 1.0 0.49 8.2 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ISP1_C PF18161.1 RUS72610.1 - 0.075 13.0 0.0 79 3.3 0.0 3.7 3 1 1 4 4 4 0 ISP1 C-terminal Apolipoprotein PF01442.18 RUS72611.1 - 0.029 14.3 12.0 0.043 13.7 12.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Synuclein PF01387.17 RUS72611.1 - 0.7 10.1 25.5 1.9 8.7 3.3 3.1 1 1 2 3 3 3 0 Synuclein DUF3498 PF12004.8 RUS72611.1 - 2 7.5 32.6 2.8 7.0 32.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TOH_N PF12549.8 RUS72611.1 - 2.6 8.0 21.3 66 3.5 0.1 8.6 4 3 6 10 10 10 0 Tyrosine hydroxylase N terminal Mucin-like PF16058.5 RUS72611.1 - 2.9 8.0 20.6 0.79 9.8 11.7 2.1 2 0 0 2 2 2 0 Mucin-like YtxH PF12732.7 RUS72611.1 - 7.5 7.2 18.6 1.8e+04 -6.0 18.6 3.0 1 1 0 1 1 1 0 YtxH-like protein Somatomedin_B PF01033.17 RUS72613.1 - 4e-08 33.5 18.7 5e-08 33.2 8.4 2.2 2 0 0 2 2 2 2 Somatomedin B domain Neuroparsin PF07327.11 RUS72613.1 - 0.027 14.9 5.5 0.035 14.6 5.5 1.2 1 0 0 1 1 1 0 Neuroparsin WAP PF00095.21 RUS72613.1 - 4.7 7.7 19.1 5 7.6 8.5 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Fer2_3 PF13085.6 RUS72614.1 - 2.9e-27 94.8 0.1 3.8e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 RUS72614.1 - 0.0023 17.8 0.1 0.0041 17.0 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PPP1R35_C PF15503.6 RUS72615.1 - 1.9e-24 86.1 1.7 6.7e-24 84.3 0.3 2.4 3 0 0 3 3 3 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Ephrin_rec_like PF07699.13 RUS72616.1 - 0.011 15.5 1.5 0.011 15.5 1.5 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like MLANA PF14991.6 RUS72616.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Cadherin_C_2 PF16492.5 RUS72616.1 - 0.3 11.9 2.1 1.1 10.1 2.1 2.0 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Ank_2 PF12796.7 RUS72620.1 - 3e-42 143.1 2.5 7.8e-16 58.4 0.0 5.5 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 RUS72620.1 - 2.2e-35 119.6 10.1 0.00014 22.1 0.2 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 RUS72620.1 - 4.7e-32 109.6 1.5 5.1e-09 36.2 0.1 8.3 5 1 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72620.1 - 2.6e-29 98.0 6.6 0.0011 19.2 0.0 10.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.6 RUS72620.1 - 3.7e-28 97.5 1.0 2.9e-08 34.1 0.1 7.2 4 1 3 7 7 7 5 Ankyrin repeats (many copies) DUF1681 PF07933.14 RUS72621.1 - 1.9e-57 193.1 0.0 2.5e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) NPF PF16601.5 RUS72621.1 - 0.0032 18.0 1.3 0.0055 17.2 1.0 1.5 1 1 0 1 1 1 1 Rabosyn-5 repeating NPF sequence-motif DUF4559 PF15112.6 RUS72622.1 - 1.1e-21 77.9 3.5 1.3e-21 77.6 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) Thioredoxin PF00085.20 RUS72622.1 - 0.066 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin CSD PF00313.22 RUS72623.1 - 9.7e-28 95.8 0.9 1.6e-27 95.1 0.9 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RUS72623.1 - 0.0076 15.9 0.0 0.0076 15.9 0.0 2.2 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF4717 PF15838.5 RUS72623.1 - 0.12 12.3 0.8 0.22 11.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) WD40 PF00400.32 RUS72625.1 - 2.1e-15 56.8 6.5 0.00012 22.8 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.8 RUS72625.1 - 0.0035 16.1 0.5 1 7.9 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 RUS72625.1 - 0.0068 16.0 0.0 0.42 10.2 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain Lectin_C PF00059.21 RUS72626.1 - 1e-93 309.3 32.4 8.2e-23 81.2 2.4 5.1 5 0 0 5 5 5 5 Lectin C-type domain UL45 PF05473.12 RUS72626.1 - 3.9e-08 33.2 18.7 0.43 10.2 0.2 5.7 4 2 1 5 5 5 5 UL45 protein, carbohydrate-binding C-type lectin-like DUF1651 PF07864.11 RUS72626.1 - 4.6e-07 30.1 0.0 2.4 8.6 0.0 5.3 5 0 0 5 5 5 1 Protein of unknown function (DUF1651) DUF5329 PF17263.2 RUS72626.1 - 7.5e-05 22.8 0.3 24 5.2 0.0 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5329) CPW_WPC PF09717.10 RUS72626.1 - 0.0033 18.4 27.2 7 7.7 1.3 6.4 5 0 0 5 5 5 3 Plasmodium falciparum domain of unknown function (CPW_WPC) Thioredoxin_2 PF13098.6 RUS72626.1 - 0.011 16.2 1.5 88 3.6 0.0 4.4 5 0 0 5 5 5 0 Thioredoxin-like domain PPR_2 PF13041.6 RUS72626.1 - 0.027 14.7 0.0 92 3.3 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family DUF2724 PF10893.8 RUS72626.1 - 1.1 9.2 5.2 18 5.2 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2724) Delta_lysin PF05372.11 RUS72626.1 - 8 5.9 15.2 30 4.0 0.1 5.1 5 0 0 5 5 5 0 Delta lysin family Neil1-DNA_bind PF09292.10 RUS72627.1 - 4.6e-09 36.1 1.5 1.2e+02 2.8 0.0 9.4 10 0 0 10 10 10 0 Endonuclease VIII-like 1, DNA bind Smoa_sbd PF17885.1 RUS72627.1 - 0.033 14.3 24.7 13 6.0 0.2 7.0 1 1 9 10 10 10 0 Styrene monooxygenase A putative substrate binding domain Mito_carr PF00153.27 RUS72628.1 - 1.1e-69 230.4 2.3 1e-24 86.2 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein adh_short_C2 PF13561.6 RUS72628.1 - 0.042 13.4 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase HTH_21 PF13276.6 RUS72628.1 - 0.062 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain DUF4698 PF15769.5 RUS72628.1 - 0.45 9.5 1.5 0.58 9.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) FAM199X PF15814.5 RUS72628.1 - 2.2 7.3 12.2 3.5 6.6 12.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF515 PF04415.12 RUS72628.1 - 3.3 6.0 5.9 4.1 5.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 RUS72628.1 - 6.3 6.3 15.7 12 5.4 15.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spermine_synth PF01564.17 RUS72629.1 - 3.8e-70 235.1 0.2 6.9e-70 234.3 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RUS72629.1 - 2e-24 85.2 0.1 3.2e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 RUS72629.1 - 5.7e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS72629.1 - 8.1e-05 23.3 0.0 0.00019 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS72629.1 - 0.00061 19.4 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF43 PF01861.16 RUS72629.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain DREV PF05219.12 RUS72629.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 RUS72629.1 - 0.017 15.8 0.0 0.1 13.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain RAG2_PHD PF13341.6 RUS72629.1 - 0.07 13.2 0.4 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 RAG2 PHD domain MADF_DNA_bdg PF10545.9 RUS72630.1 - 3.7e-15 56.0 0.7 8e-15 54.9 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2052 PF09747.9 RUS72630.1 - 0.0011 19.1 19.0 0.19 11.8 0.2 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) BESS PF02944.20 RUS72630.1 - 0.0089 15.8 0.8 0.0089 15.8 0.8 2.0 2 0 0 2 2 2 1 BESS motif PTPRCAP PF15713.5 RUS72630.1 - 0.26 11.6 22.1 4.9 7.4 18.1 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 RUS72630.1 - 0.37 10.1 16.5 0.78 9.0 16.5 1.5 1 1 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RUS72630.1 - 0.39 8.8 19.8 0.0084 14.3 11.2 2.0 2 0 0 2 2 2 0 DNA polymerase phi Connexin PF00029.19 RUS72630.1 - 0.53 10.0 2.3 0.95 9.2 2.3 1.4 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RUS72630.1 - 0.94 7.7 11.5 0.045 12.0 5.7 1.6 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS72630.1 - 1.5 8.6 10.8 1.1 9.1 7.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RPN2_C PF18004.1 RUS72630.1 - 2.2 8.2 13.6 0.16 11.8 8.0 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 RUS72630.1 - 2.2 8.4 7.3 1.6 8.9 4.6 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3408 PF11888.8 RUS72630.1 - 2.4 8.3 12.9 7.5 6.7 9.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Paf1 PF03985.13 RUS72630.1 - 4.6 6.1 23.0 0.15 11.1 15.4 2.0 2 0 0 2 2 2 0 Paf1 Radial_spoke PF04712.12 RUS72630.1 - 5.7 5.8 19.8 0.52 9.2 14.0 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein Pes-10 PF07149.11 RUS72630.1 - 5.7 5.9 16.6 0.38 9.8 9.3 2.0 2 0 0 2 2 2 0 Pes-10 FAM176 PF14851.6 RUS72630.1 - 6.4 6.4 14.3 11 5.6 10.1 2.4 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.16 RUS72630.1 - 9.8 5.3 10.7 0.62 9.2 4.9 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit 7tm_1 PF00001.21 RUS72631.1 - 2.2e-11 43.6 19.1 2.9e-11 43.2 19.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72631.1 - 9.5e-07 28.7 21.4 1.6e-06 27.9 21.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3566 PF12089.8 RUS72631.1 - 1.4 9.3 21.5 0.78 10.1 1.0 3.4 2 1 1 3 3 3 0 Transmembrane domain of unknown function (DUF3566) HMG_box_2 PF09011.10 RUS72632.1 - 1e-36 125.4 9.5 2.7e-22 79.1 5.8 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 RUS72632.1 - 3.5e-36 123.4 7.6 8.6e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.6 RUS72632.1 - 0.0015 18.5 11.9 0.27 11.2 0.2 2.4 2 1 0 2 2 2 2 HMG (high mobility group) box 5 2Fe-2S_Ferredox PF11591.8 RUS72632.1 - 4.4 7.2 6.4 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Cytomega_TRL10 PF06084.11 RUS72632.1 - 5.8 6.9 7.1 6.5 6.8 2.1 2.2 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein zf-SAP30 PF13866.6 RUS72633.1 - 2.5e-31 107.6 7.4 2.5e-31 107.6 7.4 1.8 3 0 0 3 3 3 1 SAP30 zinc-finger SAP30_Sin3_bdg PF13867.6 RUS72633.1 - 2e-20 72.9 0.2 3.8e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 BET PF17035.5 RUS72633.1 - 0.019 15.1 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation MitMem_reg PF13012.6 RUS72634.1 - 5.7e-25 87.9 0.6 1.1e-24 87.0 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RUS72634.1 - 6.3e-25 87.4 0.1 1.1e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0300 PF08594.10 RUS72634.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) NUDIX PF00293.28 RUS72635.1 - 1.1e-20 74.0 0.1 1.5e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 RUS72635.1 - 9.8e-11 41.5 0.3 2.6e-10 40.2 0.2 1.8 2 0 0 2 2 2 1 Nudix hydrolase domain UPF0086 PF01868.16 RUS72635.1 - 0.15 12.0 0.2 0.3 11.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function UPF0086 EF-hand_1 PF00036.32 RUS72636.1 - 1.2e-09 37.0 5.2 9.4e-08 31.1 0.3 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RUS72636.1 - 9.7e-09 34.9 1.8 6e-08 32.4 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS72636.1 - 1.5e-08 33.7 0.6 1.4e-06 27.5 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS72636.1 - 2.1e-08 33.4 0.5 2e-06 27.3 0.1 3.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RUS72636.1 - 5.5e-07 29.9 0.1 4.3e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 RUS72636.1 - 0.11 12.4 0.1 0.52 10.3 0.0 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 RUS72636.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB Abhydrolase_1 PF00561.20 RUS72639.1 - 0.0011 18.7 0.2 0.012 15.3 0.2 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS72639.1 - 0.0017 17.6 0.1 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS72639.1 - 0.008 16.8 2.1 0.013 16.1 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 RUS72639.1 - 0.0097 15.5 0.1 0.025 14.2 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF3432 PF11914.8 RUS72640.1 - 0.45 10.8 4.6 18 5.7 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3432) VirE3 PF06661.11 RUS72641.1 - 0.0098 15.2 0.7 0.018 14.3 0.7 1.4 1 0 0 1 1 1 1 VirE3 RAP1 PF07218.11 RUS72641.1 - 2.4 6.4 7.5 2.6 6.2 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3969 PF13108.6 RUS72642.1 - 1.4e-07 31.4 0.1 79 3.3 0.0 7.0 1 1 12 13 13 13 1 Protein of unknown function (DUF3969) MIF4G PF02854.19 RUS72642.1 - 1.7 8.2 9.6 55 3.3 0.8 4.7 1 1 4 5 5 5 0 MIF4G domain Galactosyl_T PF01762.21 RUS72644.1 - 2.3e-47 161.3 0.0 2.9e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS72644.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Fibrinogen_C PF00147.18 RUS72645.1 - 1.1e-53 182.4 0.0 1.5e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain E1_DerP2_DerF2 PF02221.15 RUS72646.1 - 1.1e-21 77.7 2.8 1.3e-21 77.4 2.8 1.1 1 0 0 1 1 1 1 ML domain Pkinase PF00069.25 RUS72648.1 - 4.7e-69 232.7 0.0 5.2e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72648.1 - 8e-39 133.5 0.0 9.4e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS72648.1 - 8.1e-06 25.0 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RUS72648.1 - 0.0059 16.0 0.1 0.024 14.0 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS72648.1 - 0.031 13.6 0.0 0.083 12.2 0.0 1.7 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 RUS72648.1 - 0.041 13.8 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RUS72648.1 - 0.081 12.5 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 RUS72649.1 - 8.1e-66 220.6 0.1 9.4e-66 220.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72649.1 - 3.9e-35 120.7 0.3 5.4e-35 120.2 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72649.1 - 3.9e-16 59.0 0.2 5.1e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS72649.1 - 7e-06 25.6 0.1 8.6e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS72649.1 - 0.00042 19.8 0.1 0.00052 19.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS72649.1 - 0.00071 19.6 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS72649.1 - 0.00074 19.5 0.3 0.74 9.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS72649.1 - 0.0012 18.5 0.5 0.0055 16.3 0.3 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 RUS72649.1 - 0.11 12.9 0.2 1.5 9.3 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS72649.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain zf-C2HC PF01530.18 RUS72651.1 - 4.8e-52 173.8 58.0 3e-15 56.1 7.4 5.4 5 0 0 5 5 5 4 Zinc finger, C2HC type zf-RanBP PF00641.18 RUS72652.1 - 4.5e-15 54.6 19.6 3e-08 32.8 7.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 RUS72652.1 - 0.00061 19.6 3.9 0.28 11.1 0.8 2.4 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3725 PF12523.8 RUS72652.1 - 0.14 12.4 0.3 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) DZR PF12773.7 RUS72652.1 - 1.8 8.6 8.9 3 7.9 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 RUS72653.1 - 2.3e-27 94.9 14.3 3.9e-27 94.2 14.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 RUS72653.1 - 0.019 15.0 1.9 0.031 14.3 1.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 RUS72653.1 - 0.2 11.4 0.4 0.2 11.4 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 RUS72653.1 - 0.22 11.1 3.0 6.6 6.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-C3HC4_2 PF13923.6 RUS72653.1 - 0.51 10.2 6.2 0.86 9.5 6.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 RUS72654.1 - 9e-10 38.3 10.9 3e-09 36.6 6.4 2.6 2 0 0 2 2 2 1 F-box-like Arf PF00025.21 RUS72654.1 - 1.8e-07 30.8 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family F-box PF00646.33 RUS72654.1 - 4.3e-05 23.3 4.7 4.3e-05 23.3 4.7 2.7 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 RUS72654.1 - 0.011 16.1 0.2 0.45 10.9 0.0 2.7 2 1 0 2 2 2 0 PRANC domain Reeler PF02014.16 RUS72655.1 - 7.8e-19 68.7 2.8 7.8e-18 65.5 2.8 2.0 1 1 0 1 1 1 1 Reeler domain Peptidase_C62 PF12380.8 RUS72655.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase DUF601 PF04642.12 RUS72656.1 - 0.24 10.9 3.6 0.27 10.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 TFIIA PF03153.13 RUS72657.1 - 5.1e-06 26.7 26.7 7.1e-06 26.3 26.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CBP_BcsG PF11658.8 RUS72657.1 - 0.00026 19.5 2.2 0.00039 19.0 2.2 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG SID-1_RNA_chan PF13965.6 RUS72657.1 - 0.00032 19.3 8.9 0.00052 18.6 8.9 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 ASC PF00858.24 RUS72657.1 - 0.0035 16.4 4.2 0.0061 15.6 4.2 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Wzy_C PF04932.15 RUS72657.1 - 0.008 15.8 7.5 0.018 14.7 7.5 1.6 1 1 0 1 1 1 1 O-Antigen ligase CitMHS PF03600.16 RUS72657.1 - 0.06 12.5 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter O_anti_polymase PF01901.16 RUS72657.1 - 0.42 9.8 18.9 1.8 7.7 18.9 1.8 1 1 0 1 1 1 0 Putative O-antigen polymerase SLC12 PF03522.15 RUS72657.1 - 1.1 8.2 29.1 1.8 7.5 29.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIIAH PF12685.7 RUS72657.1 - 5.3 6.8 31.5 0.24 11.2 19.4 2.7 2 1 0 2 2 2 0 SpoIIIAH-like protein Ion_trans PF00520.31 RUS72658.1 - 3.2e-24 85.5 13.4 3.2e-24 85.5 13.4 1.7 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 RUS72658.1 - 5.3e-10 39.2 0.1 1.6e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RUS72658.1 - 0.00029 20.8 1.0 0.00029 20.8 1.0 3.0 3 0 0 3 3 3 1 Ion channel PAS_9 PF13426.7 RUS72658.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain DUF1181 PF06680.11 RUS72658.1 - 0.0024 17.7 2.5 0.12 12.2 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1181) YL1 PF05764.13 RUS72658.1 - 1.1 9.4 14.8 0.76 9.8 5.4 2.2 2 0 0 2 2 2 0 YL1 nuclear protein wnt PF00110.19 RUS72659.1 - 2.6e-81 273.6 3.8 3.2e-81 273.3 3.8 1.0 1 0 0 1 1 1 1 wnt family RRM_1 PF00076.22 RUS72660.1 - 2.9e-64 212.8 0.5 1.2e-16 60.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS72660.1 - 2.8e-08 33.4 0.0 0.0044 16.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS72660.1 - 5.6e-07 29.3 0.0 0.12 12.3 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 RUS72660.1 - 9.6e-06 25.6 0.0 0.083 13.0 0.0 4.5 4 1 1 5 5 5 1 Limkain b1 SET_assoc PF11767.8 RUS72660.1 - 0.00018 21.1 0.0 5.3 6.8 0.0 4.4 4 0 0 4 4 4 2 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 RUS72660.1 - 0.0021 18.0 0.1 8.8 6.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Glutaredoxin PF00462.24 RUS72662.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Drf_FH1 PF06346.12 RUS72662.1 - 0.015 15.0 5.6 0.015 15.0 5.6 2.1 2 0 0 2 2 2 0 Formin Homology Region 1 SH3BGR PF04908.15 RUS72662.1 - 0.016 15.4 0.0 0.052 13.7 0.0 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein WBP-1 PF11669.8 RUS72663.1 - 0.49 11.1 0.0 0.49 11.1 0.0 2.8 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF3915 PF13054.6 RUS72663.1 - 6.6 6.7 15.1 0.1 12.6 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) MACPF PF01823.19 RUS72664.1 - 1e-18 68.2 1.5 1.5e-18 67.7 1.5 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DUF3439 PF11921.8 RUS72665.1 - 0.28 11.1 5.5 0.79 9.7 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DAG1 PF05454.11 RUS72666.1 - 3.2e-42 144.9 0.0 3.2e-42 144.9 0.0 2.2 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 RUS72666.1 - 9.6e-22 77.4 0.0 1.8e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 MLANA PF14991.6 RUS72666.1 - 0.0081 16.4 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein melan-A TMEM154 PF15102.6 RUS72666.1 - 0.0086 16.0 0.5 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 RUS72666.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Rifin Orthoreo_P10 PF07204.11 RUS72666.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 RCR PF12273.8 RUS72666.1 - 0.031 14.9 0.1 0.031 14.9 0.1 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 RUS72666.1 - 0.05 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.10 RUS72666.1 - 0.098 12.1 2.5 0.22 11.0 2.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IGFL PF14653.6 RUS72667.1 - 0.00069 19.5 10.1 0.00069 19.5 10.1 2.6 2 1 1 3 3 3 2 Insulin growth factor-like family DUF1704 PF08014.11 RUS72668.1 - 4.3e-12 45.7 2.5 4.3e-11 42.5 0.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1704) Myb_Cef PF11831.8 RUS72669.1 - 2.4e-69 233.6 6.0 2.4e-69 233.6 6.0 3.9 3 1 2 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 RUS72669.1 - 1.9e-20 72.8 6.6 9.2e-12 45.0 1.8 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS72669.1 - 2.8e-19 69.1 4.9 5.1e-13 49.1 4.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain TMV_coat PF00721.21 RUS72669.1 - 0.45 10.3 3.0 1.2 9.0 3.0 1.8 1 0 0 1 1 1 0 Virus coat protein (TMV like) GvpG PF05120.12 RUS72669.1 - 2 8.5 9.5 23 5.1 1.7 4.8 4 0 0 4 4 4 0 Gas vesicle protein G Rap1_C PF11626.8 RUS72669.1 - 2.5 8.3 7.6 0.09 12.9 0.4 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Alpha-2-MRAP_C PF06401.11 RUS72670.1 - 2e-44 152.1 24.0 2.2e-42 145.5 16.5 2.1 2 0 0 2 2 2 2 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 RUS72670.1 - 5.4e-26 90.9 31.8 5e-24 84.5 4.0 4.4 2 2 1 4 4 4 4 Alpha-2-macroglobulin RAP, N-terminal domain PRA-CH PF01502.18 RUS72670.1 - 0.049 13.5 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase DED PF01335.21 RUS72671.1 - 9.5e-15 54.7 0.3 3.5e-14 52.9 0.1 2.0 2 0 0 2 2 2 1 Death effector domain Death PF00531.22 RUS72671.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Death domain PPR_2 PF13041.6 RUS72671.1 - 0.039 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 PPR repeat family GSHPx PF00255.19 RUS72673.1 - 2.8e-22 78.3 0.0 3.7e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase LRR_6 PF13516.6 RUS72674.1 - 4e-08 32.7 11.1 0.0097 15.9 0.3 5.1 5 0 0 5 5 5 3 Leucine Rich repeat DUF1664 PF07889.12 RUS72674.1 - 0.014 15.4 1.1 0.014 15.4 1.1 5.8 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) LRR_8 PF13855.6 RUS72674.1 - 0.023 14.4 6.1 1 9.2 0.8 4.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 RUS72674.1 - 0.075 13.6 2.9 54 4.9 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat Ig_3 PF13927.6 RUS72675.1 - 0.25 11.9 2.5 0.31 11.7 0.1 2.4 3 0 0 3 3 3 0 Immunoglobulin domain CH_2 PF06294.11 RUS72677.1 - 2.2e-32 111.0 0.1 5.4e-32 109.8 0.1 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RUS72677.1 - 1.6e-14 53.5 0.1 3.9e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 RUS72677.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain PKcGMP_CC PF16808.5 RUS72677.1 - 0.027 14.3 0.1 0.027 14.3 0.1 3.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CPSF100_C PF13299.6 RUS72677.1 - 0.061 13.5 1.8 0.089 13.0 1.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pullulanase_Ins PF18494.1 RUS72677.1 - 0.12 12.8 0.4 0.28 11.7 0.4 1.6 1 0 0 1 1 1 0 Pullulanase Ins domain FAM178 PF14816.6 RUS72678.1 - 8.4e-38 130.3 8.6 1.5e-37 129.5 8.6 1.3 1 0 0 1 1 1 1 Family of unknown function, FAM178 MFS_1 PF07690.16 RUS72679.1 - 2.7e-10 39.7 37.1 1.4e-07 30.8 21.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS72679.1 - 1.6e-05 24.0 6.6 1.6e-05 24.0 6.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter GPHR_N PF12537.8 RUS72679.1 - 0.13 12.3 1.4 0.38 10.9 1.4 1.8 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Pkinase_Tyr PF07714.17 RUS72680.1 - 7.8e-56 189.2 0.0 1.2e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS72680.1 - 4.5e-27 95.1 0.0 7.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Laminin_EGF PF00053.24 RUS72680.1 - 4.3e-26 90.8 105.2 6.8e-11 42.1 12.6 6.3 6 0 0 6 6 6 5 Laminin EGF domain TIG PF01833.24 RUS72680.1 - 3.8e-18 65.3 7.3 4.2e-10 39.6 0.6 3.9 3 0 0 3 3 3 2 IPT/TIG domain TMEM154 PF15102.6 RUS72680.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 RUS72680.1 - 0.035 15.0 0.1 0.1 13.5 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4713 PF15831.5 RUS72680.1 - 2.3 8.7 9.5 6.5 7.3 9.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Cytadhesin_P30 PF07271.11 RUS72681.1 - 0.72 9.4 17.4 0.29 10.7 15.1 1.5 2 0 0 2 2 2 0 Cytadhesin P30/P32 mit_SMPDase PF14724.6 RUS72682.1 - 3.7e-82 276.6 11.0 1.4e-54 185.3 1.0 2.1 1 1 1 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase Arf PF00025.21 RUS72683.1 - 5.2e-27 94.4 0.5 6e-27 94.2 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS72683.1 - 1e-09 38.2 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72683.1 - 5.9e-09 36.2 0.1 1.4e-08 34.9 0.0 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS72683.1 - 8.8e-07 29.0 0.9 0.00031 20.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RUS72683.1 - 7.4e-05 22.1 0.4 0.0013 17.9 0.0 2.6 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 RUS72683.1 - 8.5e-05 22.6 0.2 0.00016 21.7 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS72683.1 - 8.9e-05 21.9 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS72683.1 - 0.00015 21.4 1.4 0.00036 20.1 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 RUS72683.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 RUS72683.1 - 0.0073 15.8 0.7 0.021 14.2 0.7 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RUS72683.1 - 0.008 15.9 0.2 0.44 10.3 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RUS72683.1 - 0.0095 15.5 2.9 0.066 12.7 2.9 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 RUS72683.1 - 0.0097 15.9 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 RUS72683.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS72683.1 - 0.019 15.3 0.1 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain NOG1 PF06858.14 RUS72683.1 - 0.027 14.3 0.2 0.071 12.9 0.2 1.7 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA PF00004.29 RUS72683.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RUS72683.1 - 0.12 12.5 0.2 0.39 10.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain NUC194 PF08163.12 RUS72684.1 - 1.5e-135 452.1 0.0 2.6e-135 451.3 0.0 1.4 1 0 0 1 1 1 1 NUC194 domain PI3_PI4_kinase PF00454.27 RUS72684.1 - 1.3e-48 166.0 0.1 3.1e-48 164.8 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 RUS72684.1 - 1.1e-16 61.0 0.4 2.7e-16 59.7 0.4 1.7 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 RUS72684.1 - 5e-12 45.4 0.1 1.6e-11 43.8 0.1 2.0 1 0 0 1 1 1 1 FATC domain MIT PF04212.18 RUS72684.1 - 0.003 17.6 2.3 0.0073 16.3 0.3 2.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain LRRC37AB_C PF14914.6 RUS72684.1 - 0.13 12.2 0.4 0.89 9.5 0.2 2.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Chalcone PF02431.15 RUS72684.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Chalcone-flavanone isomerase TPR_2 PF07719.17 RUS72684.1 - 0.59 10.4 2.1 44 4.5 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat OTU PF02338.19 RUS72685.1 - 1.4e-09 38.5 0.0 2.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RUS72685.1 - 0.00071 19.1 0.1 0.0026 17.2 0.0 1.9 3 0 0 3 3 3 1 Peptidase C65 Otubain Tubulin PF00091.25 RUS72686.1 - 1.6e-68 230.8 0.0 2.6e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS72686.1 - 6.3e-43 145.9 0.1 9.9e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS72686.1 - 1e-05 25.8 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS72686.1 - 0.0091 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RUS72686.1 - 0.016 14.4 0.1 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Alk_phosphatase PF00245.20 RUS72687.1 - 2.6e-35 122.2 0.1 3.2e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS72687.1 - 0.0045 16.4 0.3 0.006 16.0 0.3 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4823 PF16105.5 RUS72691.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) Scramblase PF03803.15 RUS72692.1 - 3.9e-08 32.9 0.0 5.1e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 RUS72692.1 - 0.017 14.7 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 LURP-one-related RT_RNaseH_2 PF17919.1 RUS72693.1 - 2.4e-16 59.6 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS72693.1 - 9e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase V-set PF07686.17 RUS72694.1 - 0.015 15.5 1.4 0.46 10.7 0.2 2.7 2 2 1 3 3 3 0 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS72694.1 - 0.17 12.0 0.2 5 7.2 0.1 2.7 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain TMEM154 PF15102.6 RUS72695.1 - 1.4e-05 25.0 1.1 3.1e-05 23.9 1.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family ig PF00047.25 RUS72695.1 - 0.00011 22.4 0.2 0.17 12.1 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain DUF4834 PF16118.5 RUS72695.1 - 0.00066 20.6 0.1 0.005 17.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 RUS72695.1 - 0.00067 20.5 0.2 0.0014 19.4 0.2 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RUS72695.1 - 0.0025 18.1 0.3 0.0055 17.0 0.3 1.6 1 0 0 1 1 1 1 Orf78 (ac78) V-set PF07686.17 RUS72695.1 - 0.0099 16.0 0.4 0.19 11.9 0.0 2.7 2 1 1 3 3 3 1 Immunoglobulin V-set domain Tmemb_9 PF05434.11 RUS72695.1 - 0.011 15.7 0.3 0.023 14.6 0.3 1.5 1 0 0 1 1 1 0 TMEM9 ECSCR PF15820.5 RUS72695.1 - 0.015 15.1 2.9 0.034 14.0 2.9 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Ly49 PF08391.10 RUS72695.1 - 0.02 15.2 0.5 0.02 15.2 0.5 1.7 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region DUF3169 PF11368.8 RUS72695.1 - 0.021 14.3 0.4 0.033 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Shisa PF13908.6 RUS72695.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5305 PF17231.2 RUS72695.1 - 0.027 13.9 0.3 0.065 12.6 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ig_3 PF13927.6 RUS72695.1 - 0.028 15.0 0.1 0.81 10.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain RIFIN PF02009.16 RUS72695.1 - 0.032 14.2 1.0 0.044 13.7 1.0 1.2 1 0 0 1 1 1 0 Rifin ASFV_J13L PF05568.11 RUS72695.1 - 0.042 13.6 0.2 0.077 12.7 0.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein PRIMA1 PF16101.5 RUS72695.1 - 0.066 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Protocadherin PF08374.11 RUS72695.1 - 0.066 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Protocadherin AMA-1 PF02430.15 RUS72695.1 - 0.069 12.1 0.8 0.097 11.6 0.8 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF4448 PF14610.6 RUS72695.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAG1 PF05454.11 RUS72695.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SARAF PF06682.12 RUS72695.1 - 0.076 12.7 0.6 0.21 11.2 0.1 1.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis TMEM132D_C PF15706.5 RUS72695.1 - 0.076 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Herpes_gE PF02480.16 RUS72695.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cadherin_C_2 PF16492.5 RUS72695.1 - 0.093 13.5 0.3 0.6 10.9 0.0 2.2 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Sigma_reg_N PF13800.6 RUS72695.1 - 0.094 13.0 3.1 0.19 12.0 3.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5385 PF17359.2 RUS72695.1 - 0.12 11.9 3.2 0.24 10.9 3.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF929 PF06053.11 RUS72695.1 - 0.14 11.5 1.2 0.23 10.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) TRP PF06011.12 RUS72695.1 - 0.14 10.9 1.5 0.26 10.0 1.5 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4446 PF14584.6 RUS72695.1 - 0.15 12.1 0.6 0.32 11.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SIT PF15330.6 RUS72695.1 - 0.15 12.5 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 RUS72695.1 - 0.22 11.5 1.4 0.57 10.1 1.4 1.6 1 0 0 1 1 1 0 Syndecan domain DUF3827 PF12877.7 RUS72695.1 - 0.63 8.4 5.2 1.1 7.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF2207 PF09972.9 RUS72695.1 - 5.9 5.5 6.2 37 2.9 6.2 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Vpu PF00558.19 RUS72695.1 - 6.7 6.6 6.1 13 5.7 6.1 1.4 1 0 0 1 1 1 0 Vpu protein SID-1_RNA_chan PF13965.6 RUS72696.1 - 9.7e-128 427.2 22.8 1.1e-127 427.1 22.8 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF962 PF06127.11 RUS72696.1 - 0.00047 20.2 5.6 0.34 11.0 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF962) Ceramidase PF05875.12 RUS72696.1 - 0.076 12.4 23.4 0.059 12.8 11.7 2.6 1 1 1 2 2 2 0 Ceramidase Filamin PF00630.19 RUS72697.1 - 4.7e-22 78.7 0.1 1.9e-13 51.1 0.0 2.3 2 0 0 2 2 2 2 Filamin/ABP280 repeat Big_3_5 PF16640.5 RUS72697.1 - 0.00058 20.0 0.0 0.079 13.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) FKBP_C PF00254.28 RUS72697.1 - 0.055 13.8 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase cNMP_binding PF00027.29 RUS72698.1 - 3.8e-07 30.1 0.0 7.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF5589 PF17672.1 RUS72698.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5589) cNMP_binding PF00027.29 RUS72699.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain cIII PF08134.11 RUS72699.1 - 0.83 9.4 2.3 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 cIII protein family PKD_channel PF08016.12 RUS72700.1 - 3.1e-78 263.4 10.8 4.3e-78 262.9 10.8 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RUS72700.1 - 3.7e-07 29.6 26.7 7.8e-07 28.6 26.7 1.5 1 0 0 1 1 1 1 Ion transport protein Usp PF00582.26 RUS72700.1 - 0.12 12.9 0.2 0.33 11.5 0.2 1.8 1 0 0 1 1 1 0 Universal stress protein family PKD_channel PF08016.12 RUS72701.1 - 1e-82 278.1 15.6 1e-82 278.1 15.6 2.2 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 RUS72701.1 - 6e-14 52.6 0.0 1.4e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 RUS72701.1 - 1.7e-05 24.2 27.3 1.7e-05 24.2 27.3 3.6 4 0 0 4 4 4 1 Ion transport protein GPS PF01825.21 RUS72701.1 - 0.004 17.7 0.3 0.01 16.4 0.3 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif BphX PF06139.12 RUS72702.1 - 0.0033 17.3 0.2 19 5.2 0.0 3.4 1 1 3 4 4 4 3 BphX-like EcsB PF05975.12 RUS72702.1 - 0.099 11.5 1.8 17 4.1 0.1 3.1 1 1 3 4 4 4 0 Bacterial ABC transporter protein EcsB DDA1 PF10172.9 RUS72702.1 - 0.14 12.4 13.2 9.8 6.5 0.9 3.6 1 1 2 3 3 3 0 Det1 complexing ubiquitin ligase Lipin_N PF04571.14 RUS72702.1 - 0.98 9.4 2.2 1.1e+02 2.8 0.1 3.6 1 1 3 4 4 4 0 lipin, N-terminal conserved region PKD PF00801.20 RUS72704.1 - 1.3e-13 50.6 0.7 7.1e-10 38.6 0.1 3.4 3 0 0 3 3 3 2 PKD domain Toxin_ToxA PF11584.8 RUS72704.1 - 0.12 12.4 0.0 0.48 10.4 0.0 2.0 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA TGF_beta PF00019.20 RUS72705.1 - 3.9e-32 111.3 0.2 5.7e-32 110.8 0.2 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Ufd2P_core PF10408.9 RUS72706.1 - 3.9e-128 428.8 9.3 5.3e-128 428.3 9.3 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core HAUS2 PF15003.6 RUS72707.1 - 9.4e-24 84.2 6.1 1.1e-23 83.9 6.1 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF2408 PF10303.9 RUS72707.1 - 0.0035 17.9 2.4 0.0081 16.7 2.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) BAR PF03114.18 RUS72707.1 - 0.016 14.9 0.9 0.044 13.4 0.1 2.1 2 1 0 2 2 2 0 BAR domain P22_AR_C PF10548.9 RUS72707.1 - 0.078 13.2 0.2 5.6 7.2 0.0 3.3 2 2 2 4 4 4 0 P22AR C-terminal domain Prefoldin PF02996.17 RUS72707.1 - 0.18 11.8 6.4 4.3 7.3 0.1 3.3 4 0 0 4 4 4 0 Prefoldin subunit TF_AP-2 PF03299.14 RUS72707.1 - 0.35 10.8 4.1 0.28 11.1 1.5 1.9 1 1 1 2 2 2 0 Transcription factor AP-2 DUF948 PF06103.11 RUS72707.1 - 0.53 10.6 7.8 9 6.6 3.9 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 RUS72707.1 - 1.2 9.4 5.7 2.3 8.6 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein DASH_Dad1 PF08649.10 RUS72707.1 - 3.3 8.0 5.0 6.9 6.9 0.4 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 UCH PF00443.29 RUS72708.1 - 1.8e-55 188.2 0.5 2.3e-55 187.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS72708.1 - 4.8e-19 69.1 6.4 3.1e-18 66.4 6.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RUS72708.1 - 1.1e-14 54.5 9.1 1.1e-14 54.5 9.1 3.0 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Hexapep PF00132.24 RUS72709.1 - 4.5e-12 45.2 19.0 3.4e-05 23.4 0.5 4.5 2 2 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RUS72709.1 - 1.9e-06 27.5 7.3 0.018 14.8 0.3 3.5 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 RUS72709.1 - 0.011 14.7 5.2 0.33 9.8 0.1 2.1 1 1 1 2 2 2 0 L-fucokinase DUF4954 PF16314.5 RUS72709.1 - 0.038 12.1 0.8 0.046 11.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Ras PF00071.22 RUS72710.1 - 1.7e-33 115.5 0.1 2.1e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72710.1 - 3.7e-13 49.7 0.0 6.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72710.1 - 5.9e-09 35.6 0.0 7.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS72710.1 - 1.1e-07 31.6 0.0 1.7e-05 24.5 0.1 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS72710.1 - 1.6e-06 28.2 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS72710.1 - 3.9e-06 26.9 0.1 0.0047 16.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 RUS72710.1 - 0.0028 16.7 0.2 0.13 11.2 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 RUS72710.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 RUS72710.1 - 0.029 13.5 0.1 0.17 11.0 0.1 2.1 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 RUS72710.1 - 0.043 13.6 0.1 0.14 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 RUS72710.1 - 0.047 13.7 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 RUS72710.1 - 0.077 12.8 0.2 1.5 8.6 0.1 2.3 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein TniB PF05621.11 RUS72710.1 - 0.11 11.9 0.1 0.4 10.1 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein 7tm_1 PF00001.21 RUS72711.1 - 3e-42 144.8 8.7 3.8e-42 144.4 8.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS72711.1 - 1.5e-06 27.8 4.3 2.5e-06 27.1 4.3 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS72711.1 - 2.8e-05 23.6 6.5 3.8e-05 23.2 6.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS72711.1 - 0.00018 21.3 7.7 0.00029 20.5 7.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS72711.1 - 0.021 14.6 10.5 0.4 10.4 10.5 2.5 1 1 0 1 1 1 0 Olfactory receptor Fibrinogen_C PF00147.18 RUS72712.1 - 1.4e-37 129.7 7.3 7.8e-30 104.3 0.4 2.1 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain HALZ PF02183.18 RUS72712.1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Peptidase_S8 PF00082.22 RUS72713.1 - 6.2e-42 143.9 0.0 1.3e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 RUS72713.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 RUS72713.1 - 0.02 15.3 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) 7tm_1 PF00001.21 RUS72714.1 - 7.8e-23 81.1 3.6 9.4e-23 80.9 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS72714.1 - 0.0008 19.2 9.8 0.011 15.5 7.3 2.4 2 1 0 2 2 2 2 Olfactory receptor MSA-2c PF12238.8 RUS72714.1 - 0.28 11.2 2.0 0.47 10.4 2.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-H2C2_2 PF13465.6 RUS72715.1 - 2.5e-31 106.7 116.3 2e-06 27.9 0.2 18.4 18 0 0 18 18 18 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS72715.1 - 3.4e-21 74.1 152.7 0.0046 17.7 0.8 19.6 19 0 0 19 19 19 13 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS72715.1 - 1.1e-16 60.2 149.2 0.00013 22.2 1.5 18.0 18 0 0 18 18 18 12 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS72715.1 - 1.7e-10 40.9 104.7 0.0002 21.6 3.9 15.7 17 0 0 17 17 17 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS72715.1 - 1.1e-07 31.9 93.2 0.14 12.6 3.0 14.4 14 0 0 14 14 14 8 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS72715.1 - 3.2e-06 27.3 102.0 8.7e-05 22.7 4.9 12.8 12 2 2 14 14 14 6 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RUS72715.1 - 0.00027 20.6 8.8 0.00048 19.8 4.5 13.0 16 0 0 16 16 16 4 C2H2-type zinc-finger domain Sulfotransfer_2 PF03567.14 RUS72716.1 - 8.9e-05 22.5 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Lectin_C PF00059.21 RUS72717.1 - 2.5e-34 118.3 0.0 1.1e-20 74.4 0.0 2.5 2 0 0 2 2 2 2 Lectin C-type domain Sushi PF00084.20 RUS72717.1 - 0.009 16.6 1.7 0.009 16.6 1.7 3.6 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) ShK PF01549.24 RUS72717.1 - 0.014 15.9 9.2 0.16 12.6 5.8 3.2 2 0 0 2 2 2 0 ShK domain-like DUF4612 PF15389.6 RUS72718.1 - 8.8e-10 39.6 0.0 8.8e-10 39.6 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4612) RR_TM4-6 PF06459.12 RUS72718.1 - 1.9 8.2 6.6 0.38 10.5 3.2 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1397 PF07165.11 RUS72719.1 - 0.0021 17.5 0.5 0.0026 17.2 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1397) CPG4 PF15481.6 RUS72719.1 - 0.0035 17.9 0.7 0.0046 17.6 0.3 1.4 1 1 0 1 1 1 1 Chondroitin proteoglycan 4 Fibrinogen_C PF00147.18 RUS72720.1 - 1.6e-32 113.2 0.3 1.9e-32 112.9 0.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain LBP_C PF17386.2 RUS72720.1 - 0.025 14.5 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain PHM7_cyt PF14703.6 RUS72720.1 - 0.032 14.5 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter HSBP1 PF06825.12 RUS72720.1 - 0.23 11.3 1.5 2.1 8.2 0.3 2.2 1 1 1 2 2 2 0 Heat shock factor binding protein 1 MORN PF02493.20 RUS72721.1 - 4.4e-34 114.3 40.7 2.8e-07 30.0 0.6 7.5 7 0 0 7 7 7 7 MORN repeat DUF4639 PF15479.6 RUS72721.1 - 0.033 13.2 12.4 0.044 12.8 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) BAF1_ABF1 PF04684.13 RUS72721.1 - 0.27 10.3 4.9 0.29 10.1 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TAF4 PF05236.14 RUS72721.1 - 0.36 10.5 19.8 0.47 10.1 19.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1143 PF06608.11 RUS72722.1 - 4.1e-30 104.8 1.6 5.2e-30 104.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) zf-ZPR1 PF03367.13 RUS72723.1 - 2.6e-108 358.9 0.4 1.2e-55 187.8 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 RUS72723.1 - 0.37 10.9 4.3 6.7 6.9 0.3 2.6 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_4 PF14447.6 RUS72724.1 - 4.2e-13 48.9 8.7 7.6e-13 48.1 8.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RUS72724.1 - 5e-11 42.3 8.4 8.4e-11 41.6 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS72724.1 - 5.2e-09 35.8 7.6 9.6e-09 35.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS72724.1 - 5.6e-08 33.0 8.9 1.2e-07 31.9 8.9 1.6 1 0 0 1 1 1 1 Ring finger domain UBA PF00627.31 RUS72724.1 - 5.5e-06 26.2 0.2 9.3e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain zf-C3HC4_2 PF13923.6 RUS72724.1 - 7.5e-06 25.7 9.1 1.5e-05 24.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS72724.1 - 0.00047 20.0 10.7 0.00091 19.1 10.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS72724.1 - 0.0039 17.2 11.0 0.01 15.9 11.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS72724.1 - 0.023 15.0 8.1 0.056 13.7 8.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RUS72724.1 - 0.18 11.6 10.0 0.35 10.7 10.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RUS72724.1 - 0.21 11.8 8.2 0.44 10.7 8.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 RUS72724.1 - 0.36 11.0 5.8 1.1 9.4 5.8 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 RUS72724.1 - 0.84 9.7 5.2 1.5 8.9 5.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MULE PF10551.9 RUS72725.1 - 1.7e-16 60.4 6.8 2e-09 37.7 0.1 3.0 3 0 0 3 3 3 2 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 RUS72725.1 - 2.5e-06 27.4 0.2 0.031 14.0 0.1 2.3 2 0 0 2 2 2 2 Transposase PRODH PF18327.1 RUS72725.1 - 0.0003 20.9 0.5 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Proline utilization A proline dehydrogenase N-terminal domain Lant_dehydr_C PF14028.6 RUS72725.1 - 0.011 15.3 0.3 0.03 13.9 0.2 1.8 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Imm71 PF15602.6 RUS72725.1 - 0.019 15.0 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 71 zf-primase PF09329.11 RUS72725.1 - 0.71 9.7 3.4 23 4.9 0.3 2.6 2 0 0 2 2 2 0 Primase zinc finger I-set PF07679.16 RUS72726.1 - 6.3e-37 125.5 6.1 1.2e-07 31.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 RUS72726.1 - 2.5e-36 123.7 10.8 4.6e-07 29.9 0.1 5.7 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 RUS72726.1 - 6.7e-36 122.8 11.0 6.2e-07 29.6 0.1 5.7 5 1 0 5 5 5 5 Immunoglobulin V-set domain Ig_3 PF13927.6 RUS72726.1 - 6.9e-36 122.7 9.7 8.9e-07 29.4 0.1 5.6 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 RUS72726.1 - 4.2e-15 55.9 7.2 0.0004 20.7 0.1 5.7 4 2 1 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 RUS72726.1 - 1.9e-11 43.9 0.5 0.49 10.5 0.0 5.6 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS72726.1 - 4.7e-11 42.1 0.0 0.86 9.2 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain V-set_CD47 PF08204.11 RUS72726.1 - 0.0012 18.9 7.2 2.4 8.1 0.2 5.4 5 2 0 5 5 5 1 CD47 immunoglobulin-like domain P_proprotein PF01483.20 RUS72726.1 - 0.013 15.5 0.7 80 3.4 0.0 4.9 5 0 0 5 5 5 0 Proprotein convertase P-domain G6B PF15096.6 RUS72726.1 - 0.023 14.5 0.1 20 4.9 0.0 3.4 3 0 0 3 3 3 0 G6B family Receptor_2B4 PF11465.8 RUS72726.1 - 0.031 14.5 0.0 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Gal_Lectin PF02140.18 RUS72726.1 - 0.038 14.4 1.2 8.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Galactose binding lectin domain PROCT PF08084.11 RUS72726.1 - 0.087 12.8 0.2 8.8 6.3 0.0 3.0 3 0 0 3 3 3 0 PROCT (NUC072) domain TIG_2 PF18020.1 RUS72726.1 - 0.22 12.1 1.2 9.4 6.9 0.0 3.7 4 0 0 4 4 4 0 TIG domain found in plexin GPI-anchored PF10342.9 RUS72726.1 - 3.6 8.4 9.0 57 4.6 0.2 3.9 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ig_6 PF18452.1 RUS72727.1 - 0.00061 19.3 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS72727.1 - 0.0023 18.0 0.1 0.0081 16.3 0.0 1.9 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 RUS72727.1 - 0.0029 18.2 0.1 0.012 16.2 0.0 2.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS72727.1 - 0.0048 17.1 0.0 0.0095 16.1 0.0 1.6 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 RUS72727.1 - 0.0056 16.7 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain MT-A70 PF05063.14 RUS72729.1 - 0.051 13.5 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 MT-A70 FAM92 PF06730.11 RUS72729.1 - 0.066 12.6 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein Ig_3 PF13927.6 RUS72730.1 - 1.4e-30 105.7 0.4 6.1e-12 46.0 0.4 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS72730.1 - 4.4e-30 103.6 0.3 2.1e-10 40.5 0.2 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RUS72730.1 - 1.9e-23 82.4 0.3 1.8e-07 31.2 0.5 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS72730.1 - 2.6e-17 62.9 0.2 8.8e-07 29.2 0.2 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS72730.1 - 5.8e-13 49.0 1.9 2.1e-05 24.6 0.0 4.6 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS72730.1 - 0.00047 20.2 0.1 0.062 13.4 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS72730.1 - 0.00075 19.0 0.0 0.09 12.4 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Phage_Capsid_P3 PF09018.11 RUS72730.1 - 0.021 13.7 0.1 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 P3 major capsid protein Thioredoxin_9 PF14595.6 RUS72730.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin 7tm_2 PF00002.24 RUS72731.1 - 2.1e-68 230.3 17.4 2.7e-68 229.9 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS72731.1 - 2.8e-17 62.7 1.1 6.2e-17 61.6 1.1 1.6 1 0 0 1 1 1 1 Hormone receptor domain 7tm_1 PF00001.21 RUS72732.1 - 1.3e-46 159.1 17.6 1.3e-46 159.1 17.6 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72732.1 - 1e-09 38.4 9.0 1e-09 38.4 9.0 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS72732.1 - 2e-08 34.0 17.0 3e-08 33.4 17.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS72732.1 - 6.8e-08 32.6 16.4 1.2e-07 31.8 16.4 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 RUS72732.1 - 0.00052 19.5 16.5 0.0011 18.4 16.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv LPP20 PF02169.16 RUS72732.1 - 0.15 12.4 5.7 0.35 11.2 5.7 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein TFIIA PF03153.13 RUS72732.1 - 0.4 10.6 26.2 0.62 10.0 26.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cgr1 PF03879.14 RUS72732.1 - 0.53 10.7 13.7 1.1 9.6 13.7 1.5 1 0 0 1 1 1 0 Cgr1 family DUF3040 PF11239.8 RUS72732.1 - 2.2 8.6 5.5 15 5.9 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) GPR_Gpa2_C PF11970.8 RUS72732.1 - 5 7.3 11.7 0.06 13.4 2.2 2.5 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Ribosomal_S17 PF00366.20 RUS72733.1 - 2.4e-07 30.8 1.1 3.9e-07 30.1 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 RNase_PH PF01138.21 RUS72734.1 - 3.8e-23 82.4 0.0 2.3e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS72734.1 - 4.2e-11 42.7 0.5 1.2e-10 41.2 0.5 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF473 PF04322.12 RUS72734.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF473) Complex1_30kDa PF00329.19 RUS72735.1 - 2.8e-43 147.4 0.0 4.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Castor1_N PF18700.1 RUS72735.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain PI-PLC-X PF00388.19 RUS72736.1 - 3.1e-59 198.7 0.0 6.5e-59 197.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RUS72736.1 - 1.8e-38 131.4 0.3 4.2e-38 130.2 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.24 RUS72736.1 - 3.4e-29 100.8 0.1 1.1e-15 57.4 0.0 3.0 2 0 0 2 2 2 2 SH2 domain C2 PF00168.30 RUS72736.1 - 2.1e-09 37.6 0.0 4.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 RUS72736.1 - 1.2e-07 31.5 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS72736.1 - 2.5e-05 23.8 0.0 5.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EF-hand_like PF09279.11 RUS72736.1 - 0.018 15.5 0.0 0.074 13.6 0.0 2.1 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_3_Rpc31 PF11705.8 RUS72736.1 - 1.5 9.0 6.4 4 7.6 6.4 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VWA PF00092.28 RUS72737.1 - 1.9e-09 38.0 0.0 2.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS72737.1 - 6.2e-05 23.6 0.0 0.00026 21.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF5009 PF16401.5 RUS72739.1 - 3.3e-09 36.6 1.1 3.3e-09 36.6 1.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF5009) DUF1624 PF07786.12 RUS72739.1 - 2e-08 34.1 3.6 5.9e-08 32.6 3.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 RUS72739.1 - 0.21 10.6 30.4 0.32 10.0 15.0 2.4 1 1 0 2 2 2 0 Acyltransferase family DUF3671 PF12420.8 RUS72739.1 - 0.32 11.1 2.8 0.36 10.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function GWT1 PF06423.12 RUS72739.1 - 3.6 7.7 10.8 0.12 12.6 3.1 2.4 3 0 0 3 3 3 0 GWT1 QVR PF17064.5 RUS72740.1 - 0.00013 22.2 5.0 0.00019 21.6 5.0 1.3 1 0 0 1 1 1 1 Sleepless protein Ank_2 PF12796.7 RUS72741.1 - 2.7e-15 56.7 0.1 5.4e-11 42.9 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72741.1 - 1.9e-13 50.6 0.9 1.9e-05 25.1 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72741.1 - 1.9e-12 46.2 0.7 0.079 13.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 RUS72741.1 - 7.1e-10 39.0 2.5 6.7e-05 23.1 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS72741.1 - 5.9e-09 36.0 3.5 0.0014 19.0 0.5 4.7 4 1 1 5 5 5 3 Ankyrin repeat SLAC1 PF03595.17 RUS72742.1 - 0.1 11.9 0.6 0.15 11.3 0.7 1.3 1 1 0 1 1 1 0 Voltage-dependent anion channel WSS_VP PF12175.8 RUS72742.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP SIT PF15330.6 RUS72742.1 - 0.24 11.9 0.4 0.36 11.3 0.3 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DEAD PF00270.29 RUS72743.1 - 1.7e-46 158.2 0.0 8.9e-46 155.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS72743.1 - 8.6e-29 100.1 0.1 2.2e-28 98.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS72743.1 - 0.00017 21.7 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RUS72743.1 - 0.0019 18.6 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RUS72743.1 - 0.013 15.2 0.0 0.049 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 RUS72743.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit WD40 PF00400.32 RUS72744.1 - 2.2e-15 56.7 3.2 4e-07 30.6 0.1 5.8 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72744.1 - 1.5e-12 47.6 0.0 3.9e-05 23.9 0.0 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS72744.1 - 0.0052 16.1 0.5 0.1 11.9 0.1 2.9 3 1 1 4 4 4 1 WD40-like domain Methyltransf_11 PF08241.12 RUS72745.1 - 1.9e-15 57.3 0.0 5e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS72745.1 - 4.1e-15 56.3 0.0 9.9e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS72745.1 - 1.7e-08 34.4 0.0 3.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS72745.1 - 4.8e-05 22.8 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 RUS72745.1 - 0.00013 21.6 0.1 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 RUS72745.1 - 0.00013 21.8 0.0 0.00023 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS72745.1 - 0.00021 22.0 0.0 0.00042 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS72745.1 - 0.00065 19.3 0.0 0.0015 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 RUS72745.1 - 0.042 12.4 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_zinc_N PF00107.26 RUS72745.1 - 0.059 13.4 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase LZ3wCH PF18517.1 RUS72745.1 - 0.085 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucine zipper with capping helix domain CMAS PF02353.20 RUS72745.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 RUS72745.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 RUS72745.1 - 0.25 10.7 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4731 PF15875.5 RUS72746.1 - 0.12 12.5 0.1 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) Pkinase PF00069.25 RUS72747.1 - 1.3e-61 208.3 0.0 1.9e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 RUS72747.1 - 1.1e-38 131.5 1.6 2.5e-38 130.3 0.1 2.2 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 RUS72747.1 - 5.7e-33 114.3 0.0 1.4e-32 113.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS72747.1 - 3.7e-06 26.5 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RUS72747.1 - 0.0023 16.9 2.7 0.0079 15.2 2.7 1.7 1 1 0 1 1 1 1 Haspin like kinase domain PH_8 PF15409.6 RUS72747.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 RUS72747.1 - 0.23 10.2 10.1 0.0095 14.7 2.4 2.3 2 1 0 2 2 2 0 Fungal protein kinase PH_13 PF16652.5 RUS72747.1 - 0.32 10.8 2.1 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 Pleckstrin homology domain BTB_2 PF02214.22 RUS72748.1 - 1.2e-21 76.8 0.0 2.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 RUS72748.1 - 0.03 14.6 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RING_9 PF13901.6 RUS72748.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon I-set PF07679.16 RUS72750.1 - 3.9e-13 49.3 2.4 0.00044 20.3 0.1 5.6 5 1 0 5 5 5 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS72750.1 - 6.1e-13 49.2 24.7 3.5e-06 27.5 0.2 6.6 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 RUS72750.1 - 1.2e-10 41.5 27.5 3.7e-06 27.2 0.3 6.4 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 RUS72750.1 - 1.2e-05 25.3 16.1 0.15 12.2 0.8 5.7 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain GTP1_OBG PF01018.22 RUS72750.1 - 0.055 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 GTP1/OBG GLEYA PF10528.9 RUS72750.1 - 0.13 12.7 1.9 1.2 9.6 0.1 3.4 3 1 1 4 4 4 0 GLEYA domain V-set PF07686.17 RUS72751.1 - 8.6e-07 29.1 0.1 9.4e-05 22.5 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 RUS72751.1 - 1e-06 29.2 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS72751.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS72751.1 - 1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS72751.1 - 8.3e-05 22.7 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Arabino_trans_C PF14896.6 RUS72751.1 - 0.048 12.7 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain DUF2207 PF09972.9 RUS72751.1 - 4 6.1 4.5 6.7 5.3 4.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GBR2_CC PF18455.1 RUS72753.1 - 0.00088 19.3 9.5 85 3.4 0.0 6.3 6 0 0 6 6 6 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain HNH_2 PF13391.6 RUS72753.1 - 0.0042 17.2 16.8 24 5.1 0.2 5.4 1 1 3 4 4 4 4 HNH endonuclease YaiA PF16362.5 RUS72753.1 - 0.0072 16.4 21.0 23 5.2 0.2 6.2 6 0 0 6 6 6 5 YaiA protein DUF1441 PF07278.11 RUS72753.1 - 2 8.3 15.9 66 3.4 0.1 5.6 2 1 4 6 6 6 0 Protein of unknown function (DUF1441) RVT_1 PF00078.27 RUS72754.1 - 0.01 15.4 1.0 0.015 14.8 0.2 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_psq PF05225.16 RUS72754.1 - 0.045 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Plk4_PB2 PF18409.1 RUS72754.1 - 0.075 13.7 0.8 5.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Arrestin_N PF00339.29 RUS72755.1 - 1.1e-34 119.6 0.0 9.2e-34 116.6 0.0 2.4 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS72755.1 - 8.9e-19 68.3 0.0 7.3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS72755.1 - 0.01 15.1 0.1 0.036 13.2 0.0 1.8 2 0 0 2 2 2 0 Rgp1 Vps26 PF03643.15 RUS72755.1 - 0.045 12.8 0.0 0.18 10.8 0.0 2.0 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 NusA_N PF08529.11 RUS72756.1 - 0.1 13.0 0.2 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 NusA N-terminal domain Peptidase_C48 PF02902.19 RUS72756.1 - 0.39 10.5 3.8 0.7 9.7 0.2 2.7 3 0 0 3 3 3 0 Ulp1 protease family, C-terminal catalytic domain Spaetzle PF16077.5 RUS72757.1 - 3.1e-09 37.2 0.6 4.4e-09 36.8 0.6 1.2 1 0 0 1 1 1 1 Spaetzle NGF PF00243.18 RUS72757.1 - 3.4e-06 27.3 0.2 6.4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Nerve growth factor family Eapp_C PF10238.9 RUS72758.1 - 0.065 13.3 27.0 0.82 9.7 5.3 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein AAA_11 PF13086.6 RUS72758.1 - 0.072 12.9 24.2 0.12 12.1 1.2 2.0 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.10 RUS72758.1 - 0.083 13.2 54.2 0.14 12.5 28.5 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.7 RUS72758.1 - 0.1 12.9 42.4 0.74 10.1 22.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Connexin PF00029.19 RUS72758.1 - 0.18 11.6 34.0 0.18 11.5 5.9 2.0 2 0 0 2 2 2 0 Connexin EOS1 PF12326.8 RUS72758.1 - 0.3 11.0 17.5 0.56 10.1 0.7 2.1 2 0 0 2 2 2 0 N-glycosylation protein DAG_kinase_N PF14513.6 RUS72758.1 - 0.37 11.0 23.9 1.4 9.1 3.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SpoIIP PF07454.11 RUS72758.1 - 0.57 9.6 30.5 0.17 11.3 13.8 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Rxt3 PF08642.10 RUS72758.1 - 0.61 10.9 18.9 1.2 9.9 2.1 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1764 PF08576.10 RUS72758.1 - 0.83 10.6 52.1 0.22 12.5 11.6 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CPSF100_C PF13299.6 RUS72758.1 - 0.86 9.8 27.4 2 8.6 4.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 RUS72758.1 - 1.3 9.1 20.3 4.2 7.4 1.7 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4228 PF14009.6 RUS72758.1 - 1.4 9.3 19.7 0.31 11.4 7.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF5308 PF17233.2 RUS72758.1 - 2.2 8.5 10.1 2 8.6 3.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Sec62 PF03839.16 RUS72758.1 - 2.4 7.6 43.0 3.4 7.1 11.9 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Tim54 PF11711.8 RUS72758.1 - 4 6.1 35.4 1.1 8.0 5.9 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 RUS72758.1 - 4.2 7.1 40.6 4.8 6.9 9.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 RUS72758.1 - 5 6.8 29.7 2 8.2 5.6 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus BSMAP PF12280.8 RUS72758.1 - 6 7.0 17.6 6.2 7.0 2.0 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein Ctr PF04145.15 RUS72758.1 - 7.7 7.1 10.8 22 5.6 0.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family RNA_pol_Rpc4 PF05132.14 RUS72758.1 - 9.8 6.6 39.0 7.8 6.9 20.9 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF747 PF05346.11 RUS72761.1 - 1.9e-95 320.0 21.4 2.7e-95 319.5 21.4 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family PHR PF08005.12 RUS72762.1 - 8.6e-27 94.7 0.3 1.2e-26 94.1 0.3 1.2 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 RUS72762.1 - 6.4e-10 39.3 0.0 1.8e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS72762.1 - 2.7e-08 33.9 3.7 3.6e-08 33.4 1.8 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch AKAP7_NLS PF10469.9 RUS72762.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Cu2_monoox_C PF03712.15 RUS72763.1 - 9.8e-38 129.1 0.7 1.6e-37 128.5 0.7 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RUS72763.1 - 7.3e-23 81.2 0.0 1.4e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain XPA_C PF05181.12 RUS72764.1 - 1.1e-25 89.3 0.5 1.9e-25 88.6 0.5 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 RUS72764.1 - 3.2e-14 52.7 7.9 5.2e-14 52.0 7.9 1.4 1 0 0 1 1 1 1 XPA protein N-terminal zf-C4pol PF14260.6 RUS72764.1 - 6.6 7.3 7.2 1.9 9.0 1.5 2.7 2 2 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-HYPF PF07503.12 RUS72764.1 - 7.3 6.5 7.6 4.7 7.1 1.3 2.5 2 0 0 2 2 2 0 HypF finger Trypsin PF00089.26 RUS72765.1 - 1.1e-59 202.0 0.2 1.3e-59 201.7 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS72765.1 - 1e-08 36.2 0.1 1.8e-08 35.4 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RUS72765.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Mob1_phocein PF03637.17 RUS72767.1 - 2.5e-34 118.7 0.5 3.4e-34 118.3 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF577 PF04510.12 RUS72767.1 - 0.053 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF577) DUF3338 PF11819.8 RUS72767.1 - 0.13 12.3 0.2 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) preSET_CXC PF18264.1 RUS72767.1 - 0.34 11.4 0.2 0.34 11.4 0.2 2.0 2 0 0 2 2 2 0 CXC domain FAA_hydrolase PF01557.18 RUS72768.1 - 4e-70 235.9 0.0 4.9e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family LRR_4 PF12799.7 RUS72770.1 - 1e-10 41.6 11.7 2.4e-06 27.8 3.1 4.2 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS72770.1 - 3.4e-09 36.5 4.2 4.3e-07 29.6 4.2 2.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS72770.1 - 9.8e-09 34.9 25.8 3.7e-05 23.4 5.5 3.2 1 1 3 4 4 4 4 Leucine rich repeat Tom37 PF10568.9 RUS72771.1 - 4.1e-34 117.6 0.0 6.2e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 RUS72771.1 - 5.6e-22 77.3 0.6 1.2e-21 76.3 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS72771.1 - 1.8e-18 67.1 0.0 3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain EPO_TPO PF00758.18 RUS72771.1 - 0.0012 18.9 0.2 0.0026 17.8 0.2 1.5 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin GST_N_3 PF13417.6 RUS72771.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain tRNA_U5-meth_tr PF05958.11 RUS72771.1 - 0.0099 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase GST_C_2 PF13410.6 RUS72771.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain cNMP_binding PF00027.29 RUS72772.1 - 2.3e-19 69.2 0.1 3.8e-15 55.7 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Coilin_N PF15862.5 RUS72772.1 - 0.002 17.9 7.1 0.2 11.4 0.0 2.6 2 1 0 2 2 2 1 Coilin N-terminus PEHE PF15275.6 RUS72772.1 - 0.0056 17.3 16.3 0.34 11.6 3.9 2.7 2 0 0 2 2 2 2 PEHE domain TMEM174 PF15029.6 RUS72772.1 - 0.0067 16.2 3.1 1.1 9.0 0.3 2.2 2 0 0 2 2 2 2 Transmembrane protein 174 MAM33 PF02330.16 RUS72772.1 - 0.0077 16.2 4.5 0.89 9.5 0.4 2.4 2 0 0 2 2 2 2 Mitochondrial glycoprotein Suf PF05843.14 RUS72772.1 - 0.015 15.3 10.1 0.47 10.4 1.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 RUS72772.1 - 0.085 12.5 18.0 0.68 9.5 4.1 2.2 2 0 0 2 2 2 0 Spt20 family VWD PF00094.25 RUS72772.1 - 0.11 12.7 5.8 2.2 8.5 0.3 2.7 3 0 0 3 3 2 0 von Willebrand factor type D domain RR_TM4-6 PF06459.12 RUS72772.1 - 0.13 12.1 6.5 1.9 8.2 0.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TbpB_B_D PF01298.18 RUS72772.1 - 0.15 12.5 1.3 13 6.2 0.1 2.4 2 0 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B SRP9-21 PF05486.12 RUS72772.1 - 0.17 12.3 2.6 15 6.0 0.2 2.5 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) MDM10 PF12519.8 RUS72772.1 - 0.23 10.3 4.9 0.62 8.9 0.4 2.1 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Afi1 PF07792.12 RUS72772.1 - 0.25 11.8 6.8 4.3 7.8 0.9 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking tRNA_lig_CPD PF08302.11 RUS72772.1 - 0.28 10.6 9.7 2.2 7.7 0.9 2.7 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain PPL5 PF18168.1 RUS72772.1 - 0.33 10.2 5.9 3.8 6.7 0.6 2.2 2 0 0 2 2 2 0 Prim-pol family 5 CagX PF03524.15 RUS72772.1 - 0.41 10.3 5.7 6 6.5 0.5 2.3 2 0 0 2 2 2 0 Conjugal transfer protein Baculo_PP31 PF05311.11 RUS72772.1 - 0.67 9.4 13.6 2.1 7.8 2.8 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Pex14_N PF04695.13 RUS72772.1 - 0.89 10.2 12.1 6.7 7.3 1.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ANAPC_CDC26 PF10471.9 RUS72772.1 - 2.4 9.0 26.1 9.7 7.1 9.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Eapp_C PF10238.9 RUS72772.1 - 3.4 7.7 10.3 11 6.1 1.8 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein MAS20 PF02064.15 RUS72772.1 - 5.6 7.1 15.2 4.3 7.4 2.7 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor DUF1394 PF07159.12 RUS72772.1 - 5.7 6.1 8.2 9.5 5.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1394) M_domain PF12938.7 RUS72772.1 - 6.3 6.5 25.6 7.9 6.2 8.7 2.3 2 0 0 2 2 2 0 M domain of GW182 TMEM214 PF10151.9 RUS72772.1 - 8.6 4.7 14.0 5.5 5.3 3.2 2.1 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator TMEM247 PF15444.6 RUS72772.1 - 8.6 6.3 17.4 8.8 6.3 4.9 2.4 2 0 0 2 2 2 0 Transmembrane protein 247 DUF3498 PF12004.8 RUS72774.1 - 8.1e-32 111.1 28.5 8.1e-32 111.1 28.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3498) RasGAP PF00616.19 RUS72774.1 - 1.2e-10 41.4 0.0 1.2e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Golgin_A5 PF09787.9 RUS72774.1 - 0.0003 20.4 17.5 0.00054 19.5 17.5 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 RUS72774.1 - 0.15 11.9 4.1 0.29 11.0 4.1 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) XLF PF09302.11 RUS72774.1 - 0.35 11.0 4.6 0.23 11.6 2.5 1.7 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF148 PF02520.17 RUS72774.1 - 1.4 9.0 8.9 4.5 7.4 8.9 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF148 Band_3_cyto PF07565.13 RUS72774.1 - 6.1 6.6 12.2 1.4 8.7 0.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain P_C10 PF14974.6 RUS72775.1 - 4.9e-36 123.0 0.1 5.7e-36 122.7 0.1 1.0 1 0 0 1 1 1 1 Protein C10 FAST_2 PF08368.12 RUS72775.1 - 0.1 13.4 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 SPRY PF00622.28 RUS72777.1 - 3e-18 66.1 0.1 8.1e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 RUS72777.1 - 0.072 13.5 5.0 0.13 12.6 5.0 1.4 1 0 0 1 1 1 0 SOCS box EF-hand_7 PF13499.6 RUS72778.1 - 1.6e-05 25.3 0.6 0.021 15.3 0.1 1.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS72778.1 - 0.0045 16.4 0.1 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RUS72778.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS72778.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 EF hand PAS_8 PF13188.7 RUS72778.1 - 0.12 12.4 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 PAS domain Glyco_hydro_79n PF03662.14 RUS72779.1 - 0.049 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain adh_short PF00106.25 RUS72780.1 - 4.8e-33 114.3 0.2 5.5e-32 110.8 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS72780.1 - 2.8e-20 72.9 0.0 6e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS72780.1 - 1.4e-08 34.9 0.1 5.5e-08 32.9 0.0 1.8 1 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 RUS72780.1 - 0.00018 21.7 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 RUS72780.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Baculo_LEF-11 PF06385.12 RUS72780.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Shikimate_DH PF01488.20 RUS72780.1 - 0.15 12.2 0.1 0.44 10.6 0.1 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3460 PF11943.8 RUS72780.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Ribosomal_S30 PF04758.14 RUS72781.1 - 2.2e-30 104.6 11.3 2.9e-30 104.2 11.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 RUS72781.1 - 3.1e-10 39.7 0.0 4.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Coilin_N PF15862.5 RUS72781.1 - 0.0024 17.7 0.0 0.0033 17.2 0.0 1.1 1 0 0 1 1 1 1 Coilin N-terminus Rad60-SLD PF11976.8 RUS72781.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mtr2 PF10429.9 RUS72781.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF3471 PF11954.8 RUS72782.1 - 0.057 13.9 0.0 0.081 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Antimicrobial25 PF16839.5 RUS72782.1 - 0.06 13.4 1.0 0.094 12.8 1.0 1.3 1 0 0 1 1 1 0 Nematode antimicrobial peptide Ig_3 PF13927.6 RUS72783.1 - 0.0023 18.5 0.0 0.01 16.4 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain CarbpepA_inh PF02977.15 RUS72783.1 - 0.033 14.0 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor I-set PF07679.16 RUS72784.1 - 1.3e-18 66.8 0.9 3e-08 33.6 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS72784.1 - 6e-16 58.8 2.1 9.3e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS72784.1 - 2.2e-13 50.2 2.2 2.9e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS72784.1 - 4.4e-11 42.9 3.1 4.9e-06 26.7 0.0 2.6 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS72784.1 - 3.1e-06 27.4 8.6 0.0072 16.6 0.1 3.3 2 2 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS72784.1 - 0.0027 17.2 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain DUF2550 PF10739.9 RUS72784.1 - 0.033 14.2 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) Receptor_2B4 PF11465.8 RUS72784.1 - 0.058 13.6 0.7 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Trypsin_2 PF13365.6 RUS72785.1 - 3.2e-05 24.9 0.1 0.27 12.1 0.0 3.6 3 1 0 3 3 3 2 Trypsin-like peptidase domain PPR_long PF17177.4 RUS72785.1 - 0.056 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Sulfotransfer_2 PF03567.14 RUS72786.1 - 2.5e-12 47.2 2.1 4.1e-12 46.5 2.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family SasG_E PF17041.5 RUS72786.1 - 6.8 6.8 9.9 10 6.2 1.9 2.8 2 0 0 2 2 2 0 E domain WD40 PF00400.32 RUS72789.1 - 4.9e-17 62.0 2.4 0.009 16.9 0.0 9.6 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72789.1 - 1.2e-07 31.9 0.0 0.69 10.2 0.0 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS72789.1 - 0.2 10.6 0.0 4.8 6.0 0.0 2.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM192 PF14802.6 RUS72791.1 - 1.1e-52 178.5 2.1 1.3e-52 178.3 2.1 1.0 1 0 0 1 1 1 1 TMEM192 family DUF4418 PF14387.6 RUS72791.1 - 0.064 13.5 0.7 0.064 13.5 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Tfb5 PF06331.12 RUS72792.1 - 2.6e-29 101.0 0.7 2.9e-29 100.9 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TSC22 PF01166.18 RUS72792.1 - 0.01 16.2 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family zf-C2H2_aberr PF17017.5 RUS72793.1 - 0.0014 18.8 1.9 0.11 12.6 0.3 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 RUS72793.1 - 0.024 15.1 0.5 0.024 15.1 0.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 RUS72793.1 - 0.055 13.9 4.9 1.7 9.1 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS72793.1 - 1.3 10.0 14.6 0.39 11.7 0.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger ApeC PF16977.5 RUS72794.1 - 5.6e-60 202.8 5.5 7e-60 202.5 5.5 1.1 1 0 0 1 1 1 1 C-terminal domain of apextrin TPPII_N PF12583.8 RUS72795.1 - 0.24 12.0 2.9 0.3 11.7 2.9 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal E1_DerP2_DerF2 PF02221.15 RUS72796.1 - 0.033 14.6 0.2 0.051 14.0 0.1 1.5 2 0 0 2 2 2 0 ML domain PdxA PF04166.12 RUS72797.1 - 0.083 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Inhibitor_Mig-6 PF11555.8 RUS72797.1 - 0.095 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Cupin_8 PF13621.6 RUS72799.1 - 7.5e-20 71.7 1.2 1.8e-19 70.5 0.1 1.9 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 RUS72799.1 - 3.1e-06 27.6 1.0 3e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RUS72799.1 - 0.0016 17.9 0.0 0.019 14.4 0.0 2.5 2 1 1 3 3 3 1 Cupin superfamily protein Cupin_1 PF00190.22 RUS72799.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 RUS72799.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain TPR_1 PF00515.28 RUS72799.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cupin_2 PF07883.11 RUS72799.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RNase_H PF00075.24 RUS72800.1 - 4.6e-07 30.1 0.1 1.6e-06 28.3 0.0 2.0 2 1 0 2 2 2 1 RNase H Mga PF05043.13 RUS72800.1 - 0.03 14.9 0.1 0.091 13.4 0.1 1.8 1 1 0 1 1 1 0 Mga helix-turn-helix domain Mito_carr PF00153.27 RUS72801.1 - 3.4e-33 113.4 9.0 1.7e-19 69.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein RVT_1 PF00078.27 RUS72802.1 - 2.6e-06 27.1 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Anthrax_toxA PF03497.16 RUS72802.1 - 0.15 12.2 0.3 0.22 11.7 0.3 1.2 1 0 0 1 1 1 0 Anthrax toxin LF subunit Glyco_trans_1_4 PF13692.6 RUS72803.1 - 5.4e-08 33.3 0.0 1.9e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RUS72803.1 - 6.7e-08 32.3 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RUS72803.1 - 8.3e-06 25.9 0.2 2e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 RUS72803.1 - 0.00019 21.9 0.0 0.00032 21.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RUS72803.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 PIF1 PF05970.14 RUS72804.1 - 1.1e-72 245.3 0.0 1.2e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 RUS72804.1 - 6.3e-11 42.4 0.0 8.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS72804.1 - 9.2e-05 22.8 0.0 0.00067 20.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RUS72804.1 - 0.0028 17.4 0.2 0.027 14.2 0.2 2.2 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 RUS72804.1 - 0.022 14.0 0.0 0.05 12.8 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain SNF PF00209.18 RUS72805.1 - 1.3e-161 538.8 32.3 1.7e-161 538.5 32.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AMP-binding PF00501.28 RUS72807.1 - 5.1e-89 298.8 0.0 4.7e-88 295.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DUF4577 PF15145.6 RUS72807.1 - 0.047 13.7 0.1 0.23 11.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) GP41 PF00517.17 RUS72807.1 - 0.72 9.7 3.0 1.3 8.9 3.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF3139 PF11337.8 RUS72807.1 - 1.2 9.8 6.8 3.8 8.2 6.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) CEP44 PF15007.6 RUS72808.1 - 1.1e-38 132.3 0.1 1.8e-38 131.6 0.1 1.3 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Pox_E8 PF03394.13 RUS72808.1 - 0.12 12.0 0.3 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 Poxvirus E8 protein DUF1515 PF07439.11 RUS72808.1 - 0.13 12.3 1.6 5 7.2 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) ABC_tran_CTD PF16326.5 RUS72808.1 - 0.15 12.4 1.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain LRR_4 PF12799.7 RUS72809.1 - 1.8e-14 53.6 14.7 0.00021 21.6 0.1 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS72809.1 - 1.8e-11 43.6 5.4 2.8e-08 33.4 1.4 4.2 2 2 2 4 4 4 4 Leucine rich repeat Roc PF08477.13 RUS72809.1 - 8.2e-11 42.2 0.0 8.4e-10 38.9 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 RUS72809.1 - 2.3e-10 40.6 0.0 7.8e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 RUS72809.1 - 5.1e-07 29.4 0.0 1.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 RUS72809.1 - 0.00018 22.0 0.0 0.0024 18.4 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_22 PF13401.6 RUS72809.1 - 0.015 15.6 0.0 0.11 12.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 RUS72809.1 - 0.043 13.4 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 RUS72809.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 RUS72809.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 RUS72809.1 - 0.089 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 RUS72809.1 - 0.089 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 RUS72809.1 - 0.094 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 RUS72809.1 - 0.095 12.4 0.4 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain LRR_9 PF14580.6 RUS72809.1 - 0.11 12.0 4.1 0.21 11.1 2.6 2.1 1 1 0 1 1 1 0 Leucine-rich repeat ATP-synt_ab PF00006.25 RUS72809.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 RUS72809.1 - 0.15 12.5 0.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_RNA_Pol_19 PF05320.12 RUS72809.1 - 3.5 7.6 6.1 1.4 8.8 1.6 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF1308 PF07000.11 RUS72810.1 - 9.6e-65 217.5 0.1 1.6e-64 216.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 RUS72810.1 - 1.1e-45 155.7 0.0 1.6e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5614) SelP_N PF04592.14 RUS72811.1 - 0.38 10.1 11.8 0.81 9.0 11.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.7 RUS72811.1 - 7 6.1 17.2 15 5.0 17.2 1.5 1 1 0 1 1 1 0 Invertebrate innate immunity transcript family PAH PF02671.21 RUS72812.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat CybS PF05328.12 RUS72813.1 - 1.1e-16 60.7 0.3 1.9e-16 60.0 0.3 1.4 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cu2_monoox_C PF03712.15 RUS72815.1 - 7.8e-39 132.7 0.0 7.8e-39 132.7 0.0 1.4 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RUS72815.1 - 0.047 13.9 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DUF3984 PF13136.6 RUS72815.1 - 0.077 12.4 2.5 0.097 12.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) FAM60A PF15396.6 RUS72816.1 - 0.0002 21.4 8.9 0.00027 21.0 8.9 1.2 1 0 0 1 1 1 1 Protein Family FAM60A NPR3 PF03666.13 RUS72816.1 - 0.00034 19.5 12.1 0.00043 19.2 12.1 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 RUS72816.1 - 0.00036 20.4 4.7 0.0005 19.9 4.7 1.1 1 0 0 1 1 1 1 Connexin Tim54 PF11711.8 RUS72816.1 - 0.001 18.0 4.3 0.0013 17.6 4.3 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 RUS72816.1 - 0.0086 15.3 2.1 0.0086 15.3 2.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Gti1_Pac2 PF09729.9 RUS72816.1 - 0.023 14.8 12.6 0.039 14.1 12.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family RPOL_N PF14700.6 RUS72816.1 - 0.024 14.1 11.0 0.031 13.7 11.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Na_trans_assoc PF06512.13 RUS72816.1 - 0.027 14.8 10.4 0.04 14.2 10.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF3959 PF13105.6 RUS72816.1 - 0.05 13.1 9.2 0.081 12.4 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PPL5 PF18168.1 RUS72816.1 - 0.093 12.0 14.6 0.12 11.6 14.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF4569 PF15133.6 RUS72816.1 - 0.094 12.4 7.7 0.16 11.7 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) SLC12 PF03522.15 RUS72816.1 - 0.2 10.7 12.4 0.26 10.3 12.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 RUS72816.1 - 0.21 10.4 7.9 0.28 9.9 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 RUS72816.1 - 0.23 11.9 11.2 0.61 10.5 11.2 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 MCM_bind PF09739.9 RUS72816.1 - 0.25 9.8 11.6 0.31 9.5 11.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sec62 PF03839.16 RUS72816.1 - 0.25 10.8 21.9 0.37 10.3 21.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 RUS72816.1 - 0.26 10.3 4.2 0.34 9.9 4.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF2058 PF09831.9 RUS72816.1 - 0.29 11.2 18.0 0.42 10.7 18.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3527 PF12043.8 RUS72816.1 - 0.51 9.9 9.2 0.9 9.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) SpoIIP PF07454.11 RUS72816.1 - 0.6 9.5 13.3 0.85 9.0 13.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spore_coat_CotO PF14153.6 RUS72816.1 - 0.69 9.8 18.5 1 9.2 18.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Dicty_REP PF05086.12 RUS72816.1 - 0.76 7.7 16.0 0.96 7.3 16.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GAGA_bind PF06217.12 RUS72816.1 - 0.94 9.7 16.6 1.4 9.1 16.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SART-1 PF03343.13 RUS72816.1 - 1.1 7.8 25.6 1.5 7.3 25.6 1.1 1 0 0 1 1 1 0 SART-1 family DUF913 PF06025.12 RUS72816.1 - 1.2 8.0 7.8 1.6 7.6 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RUS72816.1 - 1.3 7.7 13.8 2 7.1 13.8 1.2 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 RUS72816.1 - 1.7 8.0 13.9 2.3 7.6 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) O-ag_pol_Wzy PF14296.6 RUS72816.1 - 1.8 7.1 4.0 2.3 6.8 4.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy CDC45 PF02724.14 RUS72816.1 - 1.9 6.7 10.2 2.2 6.5 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 RUS72816.1 - 2.3 7.0 11.1 3.1 6.5 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cellulose_synt PF03552.14 RUS72816.1 - 2.5 6.5 10.0 3 6.2 10.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Membralin PF09746.9 RUS72816.1 - 2.8 6.9 7.7 3.5 6.6 7.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rtf2 PF04641.12 RUS72816.1 - 3.4 7.0 28.3 39 3.5 30.3 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Band_3_cyto PF07565.13 RUS72816.1 - 3.6 7.3 8.0 5.7 6.7 8.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2126 PF09899.9 RUS72816.1 - 3.8 5.5 6.5 5 5.1 6.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Afi1 PF07792.12 RUS72816.1 - 3.8 8.0 13.8 6.8 7.2 13.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Otopetrin PF03189.13 RUS72816.1 - 4.1 6.1 8.4 5.5 5.7 8.4 1.1 1 0 0 1 1 1 0 Otopetrin V_ATPase_I PF01496.19 RUS72816.1 - 4.6 5.0 15.9 6.1 4.6 15.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDM10 PF12519.8 RUS72816.1 - 5.1 5.9 13.0 6.5 5.5 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF908 PF06012.12 RUS72816.1 - 5.2 6.4 13.6 0.77 9.1 8.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SWI-SNF_Ssr4 PF08549.10 RUS72816.1 - 5.3 5.6 11.9 7.4 5.1 11.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SID-1_RNA_chan PF13965.6 RUS72816.1 - 5.6 5.3 5.2 6.8 5.0 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Kei1 PF08552.11 RUS72816.1 - 7.7 6.3 6.7 11 5.8 6.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3537 PF12056.8 RUS72816.1 - 8.1 5.2 5.0 11 4.7 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Chitin_synth_1N PF08407.11 RUS72817.1 - 0.86 9.6 17.4 79 3.3 0.0 6.4 2 2 2 4 4 4 0 Chitin synthase N-terminal RelB_N PF18506.1 RUS72818.1 - 0.002 17.9 2.5 0.13 12.1 0.3 3.5 3 0 0 3 3 3 1 RelB Antitoxin alpha helical domain Fringe PF02434.16 RUS72820.1 - 2e-11 43.8 0.5 3.5e-11 43.0 0.5 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS72820.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase MPS-4 PF17523.2 RUS72820.1 - 0.093 12.9 0.5 0.23 11.6 0.1 1.8 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 RVT_1 PF00078.27 RUS72821.1 - 3.6e-09 36.5 0.0 5.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fringe PF02434.16 RUS72822.1 - 2.5e-10 40.3 0.1 2.4e-09 37.0 0.1 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS72822.1 - 2.5e-06 27.4 0.0 8.4e-05 22.5 0.1 2.2 1 1 1 2 2 2 1 Galactosyltransferase Pkinase PF00069.25 RUS72823.1 - 7.1e-64 215.7 0.1 1.4e-63 214.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72823.1 - 2.1e-46 158.3 0.0 3.9e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS72823.1 - 0.0085 15.4 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RUS72823.1 - 0.021 13.6 0.1 0.021 13.6 0.1 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 RUS72823.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family L27 PF02828.16 RUS72823.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 L27 domain RNB PF00773.19 RUS72824.1 - 1.7e-97 326.7 0.0 2.9e-97 325.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RUS72824.1 - 2.9e-21 75.3 0.0 6.2e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RUS72824.1 - 8.7e-17 61.2 0.0 3e-16 59.5 0.0 1.9 1 1 1 2 2 2 1 Rrp44-like cold shock domain PIN_4 PF13638.6 RUS72824.1 - 8e-14 52.1 0.8 2.4e-13 50.5 0.8 1.9 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 RUS72824.1 - 1.5e-07 31.4 0.0 1.1e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 RUS72824.1 - 2e-07 30.9 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 RUS72824.1 - 0.035 14.4 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal DUF3689 PF12463.8 RUS72825.1 - 1.7e-131 438.2 0.9 3e-131 437.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) DUF2076 PF09849.9 RUS72826.1 - 0.0024 18.0 26.3 0.0024 18.0 26.3 2.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) PH PF00169.29 RUS72826.1 - 0.022 15.3 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 PH domain PseudoU_synth_2 PF00849.22 RUS72827.1 - 6e-27 94.7 1.2 9.2e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase adh_short_C2 PF13561.6 RUS72828.1 - 7.3e-47 159.9 0.0 9.4e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS72828.1 - 7e-42 143.1 0.1 8.5e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS72828.1 - 5.1e-08 33.0 0.3 7e-08 32.6 0.3 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS72828.1 - 0.00024 20.5 0.0 0.00064 19.1 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 RUS72828.1 - 0.0048 16.3 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 RUS72828.1 - 0.017 15.0 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bombesin PF02044.17 RUS72830.1 - 0.42 10.8 1.5 0.72 10.1 0.1 2.0 2 0 0 2 2 2 0 Bombesin-like peptide Pns11_12 PF17464.2 RUS72830.1 - 4.5 6.9 5.6 1.8 8.3 3.0 1.6 2 0 0 2 2 2 0 Non-structural protein 11 and 12 PX PF00787.24 RUS72831.1 - 6.1e-18 64.9 0.9 1.1e-17 64.0 0.9 1.4 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 RUS72831.1 - 4.6e-06 26.8 0.0 8.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS72831.1 - 0.032 14.1 0.3 0.43 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS72831.1 - 0.062 13.4 0.5 1.4 9.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 RUS72832.1 - 4.3e-15 55.8 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72832.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C101 PF16218.5 RUS72833.1 - 1.8e-80 270.1 0.0 3.1e-80 269.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C101 CCDC53 PF10152.9 RUS72833.1 - 9.5 6.6 6.4 5.1 7.5 2.9 2.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex PHD PF00628.29 RUS72835.1 - 3.2e-07 30.1 4.5 4.8e-07 29.6 3.0 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RUS72835.1 - 0.00039 20.2 2.3 0.0012 18.7 2.3 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RUS72835.1 - 0.00069 19.1 4.2 0.0024 17.4 4.2 2.0 1 1 0 1 1 1 1 PHD-finger C1_2 PF03107.16 RUS72835.1 - 0.0059 16.9 2.3 0.036 14.4 0.7 2.5 2 0 0 2 2 2 1 C1 domain FYVE_2 PF02318.16 RUS72835.1 - 2.7 8.2 6.9 0.19 11.9 0.9 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger AT_hook PF02178.19 RUS72835.1 - 5.6 7.2 8.9 0.13 12.2 2.0 2.0 2 0 0 2 2 2 0 AT hook motif Aminotran_5 PF00266.19 RUS72836.1 - 1.9e-27 96.2 0.0 2.3e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RUS72836.1 - 0.00036 19.8 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RNA_pol_Rpb4 PF03874.16 RUS72836.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 UPF0020 PF01170.18 RUS72836.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ras PF00071.22 RUS72838.1 - 1.4e-65 219.8 1.2 1.7e-65 219.6 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS72838.1 - 9.2e-37 125.9 0.1 1.5e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS72838.1 - 6.2e-17 61.6 0.3 7.5e-17 61.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS72838.1 - 5.8e-06 25.8 0.1 6.8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS72838.1 - 7.4e-06 25.5 0.2 9.5e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RUS72838.1 - 1.5e-05 25.0 1.3 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS72838.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS72838.1 - 8.6e-05 22.2 0.3 0.00026 20.6 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RUS72838.1 - 0.0098 15.6 0.2 0.5 10.1 0.0 2.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 RUS72838.1 - 0.02 15.3 0.1 0.42 11.0 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS72838.1 - 0.021 15.2 0.0 0.034 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RUS72838.1 - 0.03 13.8 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RUS72838.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS72838.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 RUS72838.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 RUS72838.1 - 0.084 11.4 0.1 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein TniB PF05621.11 RUS72838.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein HpcH_HpaI PF03328.14 RUS72838.1 - 0.12 11.5 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family RNA_helicase PF00910.22 RUS72838.1 - 0.14 12.6 0.6 0.84 10.1 0.2 2.3 1 1 1 2 2 2 0 RNA helicase ABC_tran PF00005.27 RUS72838.1 - 0.15 12.6 0.1 0.24 11.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MARVEL PF01284.23 RUS72839.1 - 0.00011 22.3 9.8 0.00018 21.6 9.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 RUS72840.1 - 4.6e-05 22.5 32.5 0.00041 19.4 32.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS72841.1 - 3.3e-18 65.7 20.6 3.3e-18 65.7 20.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HIG_1_N PF04588.13 RUS72841.1 - 0.085 13.1 0.6 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Hypoxia induced protein conserved region DUF3301 PF11743.8 RUS72841.1 - 0.089 12.5 0.4 0.21 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Meckelin PF09773.9 RUS72843.1 - 7.3e-256 851.3 2.2 1e-255 850.9 2.2 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) HSF_DNA-bind PF00447.17 RUS72844.1 - 3.4e-30 104.5 1.4 7.8e-30 103.4 1.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Nsp1_C PF05064.13 RUS72844.1 - 0.0038 17.0 1.3 0.0082 15.9 1.3 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Homeobox_KN PF05920.11 RUS72845.1 - 1.4e-06 28.1 0.1 2.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain TMEM219 PF14940.6 RUS72847.1 - 1.3e-49 168.9 0.5 6e-49 166.8 0.5 1.8 1 1 0 1 1 1 1 Transmembrane 219 HLH PF00010.26 RUS72848.1 - 7.1e-12 45.1 1.6 1.8e-11 43.8 1.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HEPN_STY4199 PF18729.1 RUS72848.1 - 0.055 12.6 0.8 0.088 12.0 0.8 1.2 1 0 0 1 1 1 0 STY4199-like HEPN IL5 PF02025.15 RUS72848.1 - 0.069 13.4 3.2 0.13 12.5 3.2 1.3 1 0 0 1 1 1 0 Interleukin 5 RRM_1 PF00076.22 RUS72850.1 - 7.5e-33 112.2 0.0 1.9e-17 62.9 0.0 2.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS72850.1 - 1.2e-07 31.6 0.0 0.0054 16.8 0.0 2.3 2 1 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 RUS72850.1 - 0.0014 18.7 0.0 0.0055 16.8 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS72850.1 - 0.091 12.8 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RUS72850.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif ANF_receptor PF01094.28 RUS72851.1 - 1.3e-06 27.8 0.1 1.6e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Sybindin PF04099.12 RUS72851.1 - 0.0026 17.7 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family ANF_receptor PF01094.28 RUS72852.1 - 7.4e-23 81.2 0.0 1e-13 51.2 0.0 2.4 2 1 0 2 2 2 2 Receptor family ligand binding region Glypican PF01153.19 RUS72853.1 - 2.6e-63 214.7 0.5 3e-63 214.5 0.5 1.0 1 0 0 1 1 1 1 Glypican CxC5 PF18718.1 RUS72853.1 - 0.1 12.7 1.9 8.4 6.5 0.1 2.3 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases Chi-conotoxin PF16981.5 RUS72853.1 - 0.18 12.0 2.8 0.42 10.9 2.8 1.6 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily TMEM208_SND2 PF05620.11 RUS72853.1 - 0.24 11.2 0.1 0.24 11.2 0.1 1.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 p450 PF00067.22 RUS72854.1 - 5e-93 312.3 0.0 6.2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transposon_TraM PF12508.8 RUS72854.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Conjugative transposon, TraM DUF3993 PF13158.6 RUS72855.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) SF3a60_bindingd PF12108.8 RUS72855.1 - 0.37 10.7 2.7 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain eIF-5_eIF-2B PF01873.17 RUS72856.1 - 4.2e-40 136.3 0.1 7.2e-40 135.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SLX9 PF15341.6 RUS72856.1 - 5.3 7.4 11.7 0.13 12.6 4.2 2.0 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 RMF PF04957.12 RUS72857.1 - 0.79 10.0 4.5 4.4 7.6 2.5 2.4 2 0 0 2 2 2 0 Ribosome modulation factor 7tm_1 PF00001.21 RUS72858.1 - 9.3e-19 67.8 3.7 1.1e-18 67.5 1.1 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TOBE_2 PF08402.10 RUS72858.1 - 1.6e-08 34.6 11.5 40 4.5 0.0 14.6 1 1 15 16 16 16 1 TOBE domain ELFV_dehydrog_N PF02812.18 RUS72860.1 - 1.3e-36 125.4 0.0 2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 RUS72860.1 - 2.1e-22 80.1 1.0 2.8e-22 79.6 1.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 RUS72860.1 - 0.017 15.2 0.4 0.028 14.5 0.4 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS72860.1 - 0.14 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fucokinase PF07959.12 RUS72861.1 - 6.1e-74 249.4 0.0 8.6e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 RUS72861.1 - 7.3e-07 29.3 0.9 7.3e-07 29.3 0.9 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RUS72861.1 - 0.002 18.5 0.0 0.0067 16.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal 7tm_1 PF00001.21 RUS72862.1 - 1.3e-09 37.8 18.3 1.7e-09 37.4 18.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72862.1 - 1.9e-08 34.3 19.1 1.9e-08 34.3 19.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Hum_adeno_E3A PF05393.11 RUS72862.1 - 0.02 14.9 2.9 0.14 12.2 0.1 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein ParA PF10609.9 RUS72864.1 - 1.5e-65 221.1 0.6 1.9e-65 220.8 0.6 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 RUS72864.1 - 2.8e-09 37.2 1.7 3.2e-08 33.7 1.7 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 RUS72864.1 - 3.5e-09 36.3 0.0 1.3e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 RUS72864.1 - 2.2e-08 34.2 0.0 3e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 RUS72864.1 - 2e-06 27.2 0.2 1.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 RUS72864.1 - 0.00077 18.5 0.4 0.0011 18.0 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 RUS72864.1 - 0.0014 18.3 0.2 0.0025 17.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 RUS72864.1 - 0.0017 17.9 0.2 0.0025 17.3 0.2 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 RUS72864.1 - 0.0057 16.2 0.1 0.017 14.6 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 RUS72864.1 - 0.0082 15.4 1.5 0.0099 15.1 0.7 1.5 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 RUS72864.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase SRP54 PF00448.22 RUS72864.1 - 0.039 13.6 0.5 0.53 9.9 0.2 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 RUS72864.1 - 0.096 12.4 0.3 0.47 10.2 0.3 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 RUS72864.1 - 0.16 12.3 0.2 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS72864.1 - 0.17 11.6 0.1 0.31 10.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS72864.1 - 0.21 12.2 0.6 0.27 11.8 0.6 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS72864.1 - 0.21 11.4 0.6 0.94 9.3 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 RUS72864.1 - 0.27 11.6 0.6 1.2 9.6 0.1 2.1 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.9 RUS72864.1 - 0.29 10.3 0.4 0.5 9.5 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 RUS72864.1 - 0.32 10.9 1.1 0.53 10.2 0.3 1.7 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 RUS72864.1 - 0.37 10.7 3.6 0.23 11.3 0.6 2.1 3 0 0 3 3 3 0 RsgA GTPase NACHT PF05729.12 RUS72864.1 - 0.59 10.0 3.5 1 9.3 1.6 2.0 2 0 0 2 2 2 0 NACHT domain BOP1NT PF08145.12 RUS72867.1 - 2.3e-96 322.7 8.5 2.3e-96 322.7 8.5 2.0 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 RUS72867.1 - 6.1e-24 83.8 5.9 5.9e-08 33.2 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS72867.1 - 4.3e-05 23.7 0.0 0.027 14.7 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VHL PF01847.16 RUS72867.1 - 0.0029 17.5 0.1 0.061 13.2 0.0 2.6 2 0 0 2 2 2 1 VHL beta domain SDA1 PF05285.12 RUS72867.1 - 0.11 11.9 19.6 0.23 10.9 19.6 1.4 1 0 0 1 1 1 0 SDA1 Malic_M PF03949.15 RUS72869.1 - 3.5e-94 314.9 0.9 4.3e-94 314.6 0.9 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RUS72869.1 - 2.4e-61 206.7 0.0 3.9e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LIM PF00412.22 RUS72871.1 - 1.1e-60 201.7 42.2 1.2e-16 60.6 2.9 4.3 4 0 0 4 4 4 4 LIM domain Nab6_mRNP_bdg PF10567.9 RUS72871.1 - 0.39 10.2 3.6 0.57 9.6 3.6 1.1 1 0 0 1 1 1 0 RNA-recognition motif zf_C2H2_13 PF18508.1 RUS72871.1 - 1.1 8.9 8.1 56 3.5 0.0 4.3 3 1 1 4 4 4 0 Zinc finger domain SR-25 PF10500.9 RUS72871.1 - 1.6 8.3 7.9 2.4 7.7 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Calpain_inhib PF00748.19 RUS72871.1 - 2.2 8.8 9.9 3.9 8.0 5.3 2.6 3 0 0 3 3 3 0 Calpain inhibitor 7tm_1 PF00001.21 RUS72872.1 - 2.8e-50 171.1 18.9 3.9e-50 170.6 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS72872.1 - 9.6e-13 48.1 17.8 2.3e-12 46.8 17.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS72872.1 - 6.1e-12 45.5 16.8 9.3e-12 44.8 16.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS72872.1 - 9.4e-09 35.4 15.4 6.4e-08 32.7 15.4 2.0 1 1 0 1 1 1 1 Olfactory receptor Pox_A9 PF04835.12 RUS72872.1 - 0.072 13.2 2.2 0.31 11.2 2.2 2.1 1 0 0 1 1 1 0 A9 protein conserved region 7TM_GPCR_Srx PF10328.9 RUS72872.1 - 3.3 7.3 29.9 1.1 8.8 19.8 3.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF3671 PF12420.8 RUS72872.1 - 4.7 7.3 9.8 2.2 8.4 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function HTH_Tnp_Tc3_2 PF01498.18 RUS72873.1 - 2.6e-05 24.4 0.2 4.4e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS72873.1 - 0.0002 21.9 0.1 0.00088 19.8 0.1 2.1 1 1 0 1 1 1 1 Homeodomain-like domain HTH_48 PF17906.1 RUS72873.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS72873.1 - 0.0095 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS72873.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 RUS72873.1 - 0.051 13.4 0.6 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain PCI PF01399.27 RUS72873.1 - 0.051 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 PCI domain DUF4817 PF16087.5 RUS72873.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS72873.1 - 0.058 13.8 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS72873.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Ank_5 PF13857.6 RUS72874.1 - 0.0002 21.6 0.3 0.0012 19.2 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS72874.1 - 0.00022 21.7 0.0 0.8 10.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72874.1 - 0.00055 20.5 0.1 0.13 12.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS72874.1 - 0.013 16.0 1.0 8 7.1 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 RUS72874.1 - 0.074 13.6 0.8 2 9.2 0.2 3.7 4 0 0 4 4 4 0 Ankyrin repeat Cation_efflux PF01545.21 RUS72876.1 - 0.00029 20.6 1.8 0.00038 20.2 1.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RUS72876.1 - 0.0062 16.6 0.5 0.56 10.4 0.0 2.3 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter TraT PF05818.12 RUS72876.1 - 0.0087 15.8 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Cadherin PF00028.17 RUS72877.1 - 3.5e-06 27.4 0.2 0.00085 19.7 0.1 2.2 2 0 0 2 2 2 2 Cadherin domain OB_aCoA_assoc PF01796.17 RUS72877.1 - 0.067 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated ARPC4 PF05856.12 RUS72879.1 - 8.9e-80 266.2 8.0 9.9e-80 266.0 8.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 RUS72879.1 - 0.011 15.8 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Sm_like domain INPP5B_PH PF16776.5 RUS72880.1 - 9.7e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Exo_endo_phos PF03372.23 RUS72880.1 - 8.9e-15 54.8 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 RUS72880.1 - 0.00037 20.4 0.0 0.0016 18.3 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain DUF5466 PF17554.2 RUS72881.1 - 0.0055 16.9 1.9 0.97 9.7 0.2 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5466) Fibrinogen_C PF00147.18 RUS72882.1 - 1.6e-100 335.4 13.3 5.2e-57 193.2 1.3 2.0 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain MRP-L51 PF10244.9 RUS72882.1 - 0.025 14.8 3.0 3.4 8.0 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit Lipoprotein_15 PF03640.15 RUS72882.1 - 0.047 13.2 3.3 1.9 8.1 0.1 2.6 2 0 0 2 2 2 0 Secreted repeat of unknown function PUD1_2 PF18457.1 RUS72882.1 - 0.36 10.8 3.4 6.2 6.8 0.3 2.4 2 0 0 2 2 2 0 Up-Regulated in long-lived daf-2 DUF4735 PF15882.5 RUS72884.1 - 1.3e-61 208.7 0.0 1.5e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) URO-D PF01208.17 RUS72885.1 - 4.3e-119 397.7 0.0 4.9e-119 397.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ank_2 PF12796.7 RUS72886.1 - 8.1e-10 39.2 0.0 2.1e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS72886.1 - 1.3e-09 38.1 0.4 0.00011 22.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72886.1 - 1.3e-09 37.4 0.1 0.00067 19.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RUS72886.1 - 1.3e-08 35.2 0.2 1.2e-06 28.9 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_9 PF12781.7 RUS72886.1 - 6.3e-07 28.8 0.0 6.3e-07 28.8 0.0 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Ank PF00023.30 RUS72886.1 - 9.3e-07 29.0 0.1 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat PX PF00787.24 RUS72887.1 - 4.2e-23 81.5 2.2 4.2e-23 81.5 2.2 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 RUS72887.1 - 1.5e-06 27.9 9.6 1e-05 25.2 9.6 2.0 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 RUS72887.1 - 0.02 14.5 7.8 0.057 13.0 7.8 1.9 1 1 0 1 1 1 0 BAR domain Helicase_C_2 PF13307.6 RUS72888.1 - 3.9e-55 186.6 0.0 6.1e-54 182.8 0.0 2.6 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RUS72888.1 - 8e-55 185.2 2.8 1.8e-54 184.0 2.8 1.6 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 RUS72888.1 - 3.2e-05 24.0 0.9 0.00044 20.3 0.1 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RUS72888.1 - 0.00051 18.9 0.0 0.0023 16.7 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain CCM2_C PF16545.5 RUS72888.1 - 0.038 14.5 0.3 0.11 13.1 0.3 1.7 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology DUF1722 PF08349.11 RUS72888.1 - 0.13 12.6 0.1 0.43 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) zf-C3HC4_3 PF13920.6 RUS72888.1 - 2 8.4 8.6 5.5 6.9 8.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAH PF02671.21 RUS72888.1 - 2 8.6 5.5 0.41 10.8 1.1 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat Isy1 PF06246.12 RUS72889.1 - 1.6e-06 27.9 4.9 6.3e-06 25.9 4.9 2.3 1 1 0 1 1 1 1 Isy1-like splicing family DUF1977 PF09320.11 RUS72889.1 - 0.48 10.7 3.2 0.78 10.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1977) ASF1_hist_chap PF04729.13 RUS72890.1 - 1.8e-70 235.8 0.1 2.3e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4490 PF14892.6 RUS72891.1 - 1.2e-09 38.1 0.4 2.6e-09 37.1 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4490) TAP35_44 PF07265.11 RUS72891.1 - 0.0012 18.8 0.1 0.0045 17.0 0.0 1.8 2 0 0 2 2 2 1 Tapetum specific protein TAP35/TAP44 VPS28 PF03997.12 RUS72892.1 - 6.7e-69 231.4 0.9 7.8e-69 231.2 0.9 1.0 1 0 0 1 1 1 1 VPS28 protein DUF1128 PF06569.11 RUS72892.1 - 0.038 14.0 0.2 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Dynactin_p22 PF07426.11 RUS72892.1 - 0.046 13.6 0.8 0.82 9.5 0.2 2.3 2 1 0 2 2 2 0 Dynactin subunit p22 ATP11 PF06644.11 RUS72893.1 - 1.4e-44 152.9 0.4 2e-44 152.5 0.4 1.1 1 0 0 1 1 1 1 ATP11 protein GARP PF16731.5 RUS72893.1 - 0.097 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma MT PF12777.7 RUS72895.1 - 6.3e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Fic_N PF13784.6 RUS72895.1 - 0.058 13.4 0.5 0.21 11.7 0.2 2.0 2 0 0 2 2 2 0 Fic/DOC family N-terminal CCDC-167 PF15188.6 RUS72895.1 - 0.53 10.7 3.8 0.3 11.5 1.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Glycos_transf_2 PF00535.26 RUS72896.1 - 8.1e-31 107.1 0.0 2.5e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS72896.1 - 1.7e-21 76.8 0.2 3.1e-21 75.9 0.1 1.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RUS72896.1 - 7.5e-06 25.5 0.0 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 RUS72896.1 - 7e-05 23.5 0.0 0.025 15.3 0.0 3.2 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 RUS72896.1 - 0.04 13.4 0.0 0.099 12.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 SIR2 PF02146.17 RUS72897.1 - 3.1e-26 92.4 2.0 4.1e-19 69.2 0.2 2.5 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 RUS72897.1 - 0.0015 18.2 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain CxC5 PF18718.1 RUS72897.1 - 0.34 11.0 3.6 0.32 11.1 0.1 2.6 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases PDZ PF00595.24 RUS72899.1 - 2.2e-39 133.7 3.1 3e-14 53.1 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 RUS72899.1 - 1.1e-18 66.8 6.3 9.4e-08 31.8 0.0 3.8 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 RUS72899.1 - 2.7e-14 53.2 0.2 2.9e-05 24.3 0.0 3.7 3 0 0 3 3 3 3 PDZ domain DUF4298 PF14131.6 RUS72900.1 - 0.06 13.3 0.6 0.06 13.3 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) NAD_binding_2 PF03446.15 RUS72900.1 - 0.17 12.0 0.9 0.68 10.1 0.2 2.1 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-RING_9 PF13901.6 RUS72900.1 - 0.19 11.7 4.7 0.2 11.6 3.9 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon CENP-Q PF13094.6 RUS72900.1 - 0.96 9.6 9.5 1.9 8.6 0.1 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MA3 PF02847.17 RUS72901.1 - 0.013 15.5 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 MA3 domain CDC45 PF02724.14 RUS72902.1 - 8.2 4.6 8.9 11 4.2 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein MGC-24 PF05283.11 RUS72903.1 - 1.2 9.5 11.9 0.098 13.1 3.3 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AAA PF00004.29 RUS72904.1 - 3.7e-38 131.0 0.0 7.7e-38 129.9 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS72904.1 - 5.2e-10 39.0 0.0 1.1e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 RUS72904.1 - 6.2e-07 29.3 0.0 2.5e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 RUS72904.1 - 5.7e-06 26.4 0.0 1.8e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS72904.1 - 4.7e-05 23.2 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS72904.1 - 0.00054 20.1 0.0 0.0016 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RUS72904.1 - 0.00061 20.2 3.2 0.075 13.4 0.1 2.8 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RUS72904.1 - 0.00077 19.8 1.5 0.058 13.7 1.5 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RUS72904.1 - 0.026 13.7 0.1 0.055 12.7 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 RUS72904.1 - 0.035 13.5 0.2 0.1 11.9 0.2 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RUS72904.1 - 0.04 13.5 0.6 7.2 6.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 RUS72904.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 RUS72904.1 - 0.085 12.3 0.8 15 4.9 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 RUS72904.1 - 0.15 11.4 1.1 5.3 6.3 1.1 2.7 1 1 0 1 1 1 0 KaiC AAA_24 PF13479.6 RUS72904.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS72904.1 - 0.18 12.4 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RUS72904.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-C2H2 PF00096.26 RUS72909.1 - 0.03 14.8 1.2 0.03 14.8 1.2 9.3 9 1 1 10 10 10 0 Zinc finger, C2H2 type AT_hook PF02178.19 RUS72909.1 - 0.4 10.7 2.7 2.2 8.4 2.7 2.3 1 0 0 1 1 1 0 AT hook motif SPC12 PF06645.13 RUS72910.1 - 1.5e-25 89.1 1.0 1.8e-25 88.8 1.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) NAD_binding_8 PF13450.6 RUS72911.1 - 1.1e-11 44.8 0.3 3.8e-11 43.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 RUS72911.1 - 1.3e-07 31.3 0.7 5.5e-06 25.9 0.7 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 RUS72911.1 - 2.4e-05 24.1 0.2 0.00091 18.9 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 RUS72911.1 - 0.00032 20.7 0.1 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 RUS72911.1 - 0.0025 17.1 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS72911.1 - 0.0063 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS72911.1 - 0.0099 15.0 0.7 0.018 14.2 0.5 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 RUS72911.1 - 0.018 15.6 0.1 3.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NNMT_PNMT_TEMT PF01234.17 RUS72911.1 - 0.06 12.5 0.1 11 5.2 0.1 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family HI0933_like PF03486.14 RUS72911.1 - 0.061 12.0 0.1 0.66 8.6 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 RUS72911.1 - 0.14 11.4 0.6 0.43 9.9 0.7 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ank_2 PF12796.7 RUS72912.1 - 6e-20 71.6 0.2 6.5e-13 49.1 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS72912.1 - 1.6e-10 41.3 0.4 0.00089 19.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS72912.1 - 2.9e-09 37.0 0.1 0.048 14.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72912.1 - 3.7e-07 29.9 0.0 0.025 15.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RUS72912.1 - 3.9e-06 27.1 0.0 0.014 15.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 RUS72915.1 - 3.9e-48 164.1 0.0 4.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72915.1 - 2.9e-28 98.8 0.0 4.6e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 RUS72915.1 - 4.7e-12 45.7 0.1 3e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 RUS72915.1 - 0.00038 20.1 0.0 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 RUS72915.1 - 0.0018 18.2 0.1 0.32 10.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS72915.1 - 0.0023 17.3 0.0 0.0048 16.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RUS72915.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TAFII28 PF04719.14 RUS72916.1 - 3.1e-39 132.9 0.1 6e-39 132.0 0.1 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 RUS72916.1 - 5.9e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AC_N PF16214.5 RUS72916.1 - 0.42 9.7 5.1 0.51 9.4 5.1 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region SR-25 PF10500.9 RUS72916.1 - 1.3 8.6 28.2 0.26 10.9 24.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein LAP1C PF05609.12 RUS72916.1 - 1.9 7.5 9.8 2.4 7.2 9.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Kelch_1 PF01344.25 RUS72917.1 - 1.8e-42 142.6 1.9 4.1e-13 48.7 0.0 7.3 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 RUS72917.1 - 4.1e-30 103.1 0.3 8.9e-08 32.2 0.0 6.3 4 2 2 6 6 6 5 Kelch motif BACK PF07707.15 RUS72917.1 - 5.8e-25 87.4 0.7 1.4e-24 86.2 0.7 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 RUS72917.1 - 6.7e-25 87.5 0.1 1.2e-24 86.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RUS72917.1 - 6.6e-22 76.6 0.2 4.3e-05 23.3 0.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 RUS72917.1 - 4.2e-16 58.8 0.1 0.0021 18.3 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS72917.1 - 2.9e-15 55.9 0.2 0.0011 18.9 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 RUS72917.1 - 6.9e-15 54.8 0.8 0.00016 21.6 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain DUF3342 PF11822.8 RUS72917.1 - 0.02 15.1 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Dus PF01207.17 RUS72918.1 - 4e-67 226.5 0.0 4.8e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RUS72918.1 - 3.3e-06 26.7 0.1 6.1e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 RUS72918.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase PdxJ PF03740.13 RUS72918.1 - 0.015 14.4 0.5 0.023 13.8 0.5 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 RUS72918.1 - 0.072 12.5 0.0 3.2 7.1 0.0 2.2 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PEP_mutase PF13714.6 RUS72918.1 - 0.11 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase SOR_SNZ PF01680.17 RUS72918.1 - 0.11 12.2 1.1 0.49 10.2 0.7 2.1 1 1 1 2 2 2 0 SOR/SNZ family Ank_2 PF12796.7 RUS72919.1 - 1.1e-25 90.0 0.0 1.9e-14 54.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS72919.1 - 1.6e-25 88.3 0.1 3.4e-05 24.1 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 RUS72919.1 - 5e-20 71.6 0.3 3.2e-09 37.1 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS72919.1 - 1.2e-19 68.3 0.0 8.5e-05 22.7 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 RUS72919.1 - 2.1e-19 69.3 1.2 7.1e-12 45.3 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 RUS72919.1 - 4.2e-10 39.9 0.2 1e-09 38.7 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS72919.1 - 1.6e-07 31.4 0.2 6e-07 29.5 0.2 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Dicty_CTDC PF00526.18 RUS72919.1 - 0.58 10.1 5.4 1.7 8.6 5.4 1.8 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat RtcB PF01139.17 RUS72920.1 - 3.5e-115 385.5 0.7 6.4e-113 378.0 0.7 2.7 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB RRM_1 PF00076.22 RUS72921.1 - 2.3e-13 49.8 0.0 3.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS72921.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif AP-5_subunit_s1 PF15001.6 RUS72921.1 - 0.54 10.2 5.2 1 9.3 5.2 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4937 PF16291.5 RUS72921.1 - 5.1 7.4 8.8 13 6.1 2.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4937 GyrI-like PF06445.15 RUS72922.1 - 0.011 16.0 0.3 0.035 14.4 0.1 1.9 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Hist_deacetyl PF00850.19 RUS72923.1 - 7.9e-50 170.1 0.0 1.2e-49 169.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain UPF0640 PF15114.6 RUS72924.1 - 3.6e-27 94.0 1.8 4e-27 93.8 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 DUF4516 PF14990.6 RUS72925.1 - 3e-17 62.1 0.1 3.8e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) Neur_chan_LBD PF02931.23 RUS72926.1 - 1.7e-38 132.2 1.1 3e-38 131.5 1.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS72926.1 - 1e-09 38.8 0.5 1.8e-09 38.1 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GWT1 PF06423.12 RUS72926.1 - 0.0054 16.9 3.2 0.0079 16.3 1.5 2.1 2 0 0 2 2 2 1 GWT1 Neur_chan_memb PF02932.16 RUS72927.1 - 2e-07 31.4 17.1 1.3e-06 28.7 0.3 3.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Nudix_hydro PF18290.1 RUS72927.1 - 0.0094 15.9 0.4 0.017 15.1 0.4 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain XH PF03469.14 RUS72927.1 - 0.011 15.6 1.4 0.022 14.7 1.4 1.4 1 0 0 1 1 1 0 XH domain MFS_2 PF13347.6 RUS72927.1 - 0.019 13.5 1.0 0.034 12.7 0.1 1.6 2 0 0 2 2 2 0 MFS/sugar transport protein PalH PF08733.10 RUS72927.1 - 0.053 12.5 0.3 0.084 11.9 0.3 1.3 1 0 0 1 1 1 0 PalH/RIM21 YrhC PF14143.6 RUS72927.1 - 0.17 12.0 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 YrhC-like protein Ninjurin PF04923.12 RUS72927.1 - 0.4 10.6 2.6 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Ninjurin RecO_N PF11967.8 RUS72929.1 - 0.46 10.5 2.1 38 4.4 0.0 3.7 4 0 0 4 4 4 0 Recombination protein O N terminal DHH PF01368.20 RUS72932.1 - 0.034 14.4 0.0 0.49 10.7 0.0 2.7 3 1 0 3 3 3 0 DHH family BCMA-Tall_bind PF09257.10 RUS72934.1 - 0.68 10.1 11.0 3.4 7.8 1.1 2.8 2 1 0 2 2 2 0 BCMA, TALL-1 binding GPDPase_memb PF10110.9 RUS72934.1 - 5.1 5.8 10.1 5.9 5.6 1.8 2.0 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Nucleos_tra2_C PF07662.13 RUS72935.1 - 3.8e-43 147.8 1.5 4.2e-43 147.6 1.5 1.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Y_phosphatase PF00102.27 RUS72937.1 - 7e-141 467.6 1.8 1.9e-78 263.3 0.3 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 RUS72937.1 - 2.5e-09 37.0 0.0 0.0011 18.7 0.0 2.8 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS72937.1 - 7.8e-07 29.3 0.0 0.00065 19.7 0.0 2.7 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RUS72937.1 - 0.051 13.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF4006 PF13179.6 RUS72937.1 - 2.3 8.2 6.5 71 3.4 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) YL1 PF05764.13 RUS72938.1 - 0.00022 21.4 4.5 0.00024 21.3 4.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein DUF4770 PF15994.5 RUS72938.1 - 0.0017 18.6 1.4 0.0024 18.2 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) SR-25 PF10500.9 RUS72938.1 - 0.0023 17.6 25.4 0.0034 17.0 25.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1764 PF08576.10 RUS72938.1 - 0.0025 18.7 9.9 0.0047 17.8 9.9 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 RUS72938.1 - 0.0039 17.0 0.8 0.0047 16.7 0.8 1.1 1 0 0 1 1 1 1 Connexin AP3D1 PF06375.11 RUS72938.1 - 0.0042 17.3 17.8 0.0068 16.7 17.8 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Eapp_C PF10238.9 RUS72938.1 - 0.0045 17.1 0.2 0.0058 16.7 0.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Vfa1 PF08432.10 RUS72938.1 - 0.034 14.5 13.2 0.044 14.1 12.3 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.7 RUS72938.1 - 0.041 14.2 8.8 0.068 13.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PPL5 PF18168.1 RUS72938.1 - 0.043 13.1 4.0 0.058 12.7 4.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 RUS72938.1 - 0.044 14.2 5.8 0.067 13.6 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 RUS72938.1 - 0.056 11.7 1.0 0.066 11.5 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SLD3 PF08639.10 RUS72938.1 - 0.097 11.4 11.0 0.13 11.0 11.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 GAGA_bind PF06217.12 RUS72938.1 - 0.12 12.7 11.4 0.16 12.2 11.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CLN3 PF02487.17 RUS72938.1 - 0.18 10.9 0.8 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 CLN3 protein EIIBC-GUT_N PF03612.14 RUS72938.1 - 0.2 11.4 5.9 0.3 10.8 5.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1387 PF07139.11 RUS72938.1 - 0.21 11.3 17.1 0.32 10.7 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Topoisom_I_N PF02919.15 RUS72938.1 - 0.33 10.4 13.6 0.49 9.9 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Peptidase_S49_N PF08496.10 RUS72938.1 - 0.4 10.7 16.7 0.58 10.2 16.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Thg1C PF14413.6 RUS72938.1 - 0.54 10.4 8.5 0.82 9.8 8.5 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain HA2 PF04408.23 RUS72938.1 - 0.61 10.4 3.9 1 9.7 3.9 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) OATP PF03137.20 RUS72938.1 - 0.75 8.0 3.3 0.98 7.6 3.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ferlin_C PF16165.5 RUS72938.1 - 0.82 9.6 12.3 1.5 8.7 12.3 1.4 1 0 0 1 1 1 0 Ferlin C-terminus NPR3 PF03666.13 RUS72938.1 - 0.86 8.3 7.5 1.1 7.9 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Folate_carrier PF01770.18 RUS72938.1 - 0.91 8.2 2.1 1.2 7.8 2.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier CMS1 PF14617.6 RUS72938.1 - 0.92 8.8 13.7 1.3 8.3 13.7 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit eIF_4EBP PF05456.11 RUS72938.1 - 1 9.3 5.7 1.8 8.5 5.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PcfK PF14058.6 RUS72938.1 - 1.3 9.3 17.0 1.9 8.8 17.0 1.2 1 0 0 1 1 1 0 PcfK-like protein DUF3464 PF11947.8 RUS72938.1 - 1.4 8.6 13.7 2.1 8.1 13.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 NARP1 PF12569.8 RUS72938.1 - 1.7 7.4 15.1 2.2 7.1 15.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.14 RUS72938.1 - 1.8 7.0 3.4 2.2 6.7 3.4 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4448 PF14610.6 RUS72938.1 - 2.1 8.1 7.6 4.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1168 PF06658.12 RUS72938.1 - 2.1 8.1 23.6 3 7.7 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) ORC5_C PF14630.6 RUS72938.1 - 2.5 7.6 7.1 3.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus MAP17 PF15807.5 RUS72938.1 - 2.6 8.3 8.0 4.1 7.7 8.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 VKG_Carbox PF05090.14 RUS72938.1 - 3 6.6 3.8 4 6.2 3.8 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Sec62 PF03839.16 RUS72938.1 - 5.6 6.4 13.6 7.8 5.9 13.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FancD2 PF14631.6 RUS72938.1 - 6.6 4.0 7.6 8 3.7 7.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Jak1_Phl PF17887.1 RUS72938.1 - 8 6.4 12.3 13 5.7 12.3 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain FAM199X PF15814.5 RUS72938.1 - 8.3 5.4 6.3 47 2.9 7.3 1.6 2 0 0 2 2 2 0 Protein family FAM199X Cadherin PF00028.17 RUS72939.1 - 2e-94 310.2 11.0 1.1e-18 67.5 0.1 9.4 10 0 0 10 10 10 8 Cadherin domain Cadherin_2 PF08266.12 RUS72939.1 - 1.4e-06 28.0 0.0 5.4 6.9 0.0 4.9 5 0 0 5 5 5 3 Cadherin-like Invasin_D3 PF09134.10 RUS72939.1 - 0.051 13.9 3.1 0.63 10.4 0.0 4.2 4 0 0 4 4 4 0 Invasin, domain 3 RIFIN PF02009.16 RUS72939.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Rifin NOD PF06816.13 RUS72939.1 - 0.1 12.2 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 NOTCH protein AIG1 PF04548.16 RUS72940.1 - 2.5e-30 105.4 0.0 3.6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS72940.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PspB PF06667.12 RUS72940.1 - 0.035 14.2 1.0 5.3 7.2 0.3 2.6 2 0 0 2 2 2 0 Phage shock protein B Dynamin_N PF00350.23 RUS72940.1 - 0.045 13.8 2.8 2.4 8.2 0.8 2.8 2 1 1 3 3 3 0 Dynamin family DUF3040 PF11239.8 RUS72940.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) ABC_tran PF00005.27 RUS72940.1 - 0.15 12.6 0.3 0.33 11.4 0.3 1.6 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 RUS72941.1 - 3.4e-33 114.8 0.0 4.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS72941.1 - 2.3e-08 34.1 0.0 4.7e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS72941.1 - 0.0044 16.9 0.3 0.0085 16.0 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 RUS72941.1 - 0.0064 16.6 3.4 1.2 9.2 1.0 3.0 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 RUS72941.1 - 0.044 14.3 0.2 0.1 13.1 0.1 1.6 2 0 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 RUS72941.1 - 0.087 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Qua1 PF16274.5 RUS72941.1 - 0.09 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Qua1 domain MFS_1 PF07690.16 RUS72942.1 - 3.8e-30 105.0 37.9 3.2e-25 88.8 14.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS72942.1 - 2.8 6.7 21.5 0.39 9.5 6.9 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 RUS72943.1 - 5e-34 117.8 13.0 1.7e-27 96.3 5.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS72943.1 - 8.3e-07 28.2 0.0 0.008 15.1 0.0 2.4 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 RUS72943.1 - 3.6 6.3 24.1 2 7.2 13.5 3.1 2 1 0 2 2 2 0 Sugar (and other) transporter CDP-OH_P_transf PF01066.21 RUS72944.1 - 0.34 11.7 1.6 1.8 9.4 0.1 2.2 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.21 RUS72945.1 - 0.016 16.0 4.1 0.016 15.9 0.0 3.0 3 0 0 3 3 3 0 CDP-alcohol phosphatidyltransferase XAP5 PF04921.14 RUS72946.1 - 5.3e-88 295.0 11.0 5.3e-88 295.0 11.0 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Tubulin_2 PF13809.6 RUS72946.1 - 0.1 11.7 2.3 0.099 11.8 1.1 1.7 1 1 0 1 1 1 0 Tubulin like F420_oxidored PF03807.17 RUS72948.1 - 3.2e-11 43.6 0.0 1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RUS72948.1 - 0.00027 21.1 0.0 0.00068 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RUS72948.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 RUS72948.1 - 0.024 14.3 0.0 0.073 12.7 0.0 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 RUS72948.1 - 0.026 14.8 0.0 0.085 13.1 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 RUS72948.1 - 0.12 12.2 0.1 1.4 8.8 0.0 2.7 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FERM_M PF00373.18 RUS72949.1 - 9.3e-40 135.7 0.1 2.5e-39 134.3 0.1 1.8 1 1 0 1 1 1 1 FERM central domain PH PF00169.29 RUS72949.1 - 3.4e-06 27.5 0.0 9.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 PH domain TPR_2 PF07719.17 RUS72950.1 - 1.1e-27 93.9 11.2 0.0047 16.9 0.5 9.3 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 RUS72950.1 - 9.3e-25 85.4 8.5 2e-05 24.2 0.1 8.0 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 RUS72950.1 - 1.3e-19 68.7 0.8 0.14 12.5 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 RUS72950.1 - 2.3e-19 69.5 12.0 0.00017 21.8 0.0 6.9 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 RUS72950.1 - 2.4e-16 59.0 8.0 0.0086 16.8 0.1 7.7 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS72950.1 - 3.6e-15 56.2 4.3 0.0025 18.3 0.7 5.5 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS72950.1 - 2.3e-13 49.1 9.1 0.54 10.4 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS72950.1 - 5.7e-09 36.5 11.3 0.0002 21.9 0.5 5.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS72950.1 - 2.4e-08 34.1 9.8 0.48 11.2 0.1 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS72950.1 - 1.3e-07 31.5 10.0 0.0032 17.7 0.2 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS72950.1 - 4.7e-06 26.7 19.2 0.004 17.3 4.8 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RUS72950.1 - 3.4e-05 23.4 6.6 1.1 9.0 0.0 5.7 5 1 1 6 6 6 2 TPR repeat TPR_10 PF13374.6 RUS72950.1 - 3.8e-05 23.4 6.3 0.35 10.8 0.1 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 RUS72950.1 - 7.3e-05 22.1 4.5 0.00023 20.5 1.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 RUS72950.1 - 0.00086 18.8 0.4 0.0033 16.9 0.2 2.1 2 1 0 2 2 2 1 Coatomer epsilon subunit PPR PF01535.20 RUS72950.1 - 0.004 17.3 0.2 83 3.8 0.1 4.8 4 0 0 4 4 4 0 PPR repeat TPR_9 PF13371.6 RUS72950.1 - 0.0045 17.1 4.6 2.7 8.2 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF5112 PF17139.4 RUS72950.1 - 0.017 14.6 4.1 0.75 9.2 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) PknG_TPR PF16918.5 RUS72950.1 - 0.026 13.2 0.4 0.045 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS72950.1 - 0.032 14.3 9.0 0.86 9.7 0.1 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 RUS72950.1 - 0.079 12.0 0.7 4.8 6.1 0.0 2.6 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 RUS72950.1 - 0.079 13.0 2.0 0.36 10.8 0.1 2.8 3 0 0 3 3 3 0 Putative TPR-like repeat PPTA PF01239.22 RUS72950.1 - 0.09 12.5 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Glyoxalase PF00903.25 RUS72950.1 - 0.17 12.1 0.1 4.8 7.4 0.1 2.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF5575 PF17738.1 RUS72952.1 - 2.9e-14 52.8 7.0 4.9e-13 48.8 7.0 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5575) PHD PF00628.29 RUS72952.1 - 0.00019 21.3 3.7 0.00062 19.6 3.7 1.9 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.17 RUS72952.1 - 0.0011 18.6 0.1 0.0031 17.1 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger UNC45-central PF11701.8 RUS72952.1 - 0.042 13.8 0.8 2.9 7.8 0.0 3.3 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central PTPS_related PF10131.9 RUS72952.1 - 0.054 11.8 0.0 0.084 11.2 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FAR1 PF03101.15 RUS72952.1 - 0.096 13.4 2.0 0.27 12.0 2.0 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Prok-RING_1 PF14446.6 RUS72952.1 - 0.1 12.5 4.1 0.038 13.9 0.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MULE PF10551.9 RUS72952.1 - 0.42 11.1 2.3 7 7.1 0.1 3.4 3 0 0 3 3 3 0 MULE transposase domain Pkinase PF00069.25 RUS72953.1 - 2.7e-37 128.6 0.0 1.4e-26 93.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS72953.1 - 2.3e-14 53.3 0.0 1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RUS72953.1 - 0.0004 20.4 0.0 0.078 12.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS72953.1 - 0.037 12.8 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RUS72953.1 - 0.085 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS72953.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 RUS72953.1 - 0.16 11.6 0.2 0.51 9.9 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SchA_CurD PF04486.12 RUS72955.1 - 2.4e-11 43.8 2.9 5.5 7.1 0.0 9.3 3 2 10 13 13 13 4 SchA/CurD like domain Filamin PF00630.19 RUS72955.1 - 0.00051 20.8 0.2 0.023 15.5 0.2 2.8 1 1 0 1 1 1 1 Filamin/ABP280 repeat IF-2 PF11987.8 RUS72955.1 - 0.0006 19.9 7.3 0.77 9.9 0.1 5.5 1 1 5 7 7 7 1 Translation-initiation factor 2 YebF PF13995.6 RUS72955.1 - 0.0023 17.9 3.6 6.1 6.9 0.1 4.8 1 1 2 5 5 5 1 YebF-like protein DUF4382 PF14321.6 RUS72955.1 - 0.011 16.0 6.4 7.4 6.8 0.1 4.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4382) DUF3164 PF11363.8 RUS72955.1 - 0.18 11.4 3.6 5.5 6.5 0.0 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF3164) DUF5093 PF17011.5 RUS72955.1 - 0.36 11.1 22.6 1.9 8.8 2.0 4.4 1 1 3 5 5 5 0 Domain of unknown function (DUF5093) BetaGal_dom4_5 PF13364.6 RUS72955.1 - 0.39 11.3 3.1 2.4 8.7 0.1 3.4 2 2 2 4 4 4 0 Beta-galactosidase jelly roll domain MuF_C PF18819.1 RUS72955.1 - 1.1 9.2 9.5 8.2 6.5 0.2 4.4 2 2 3 5 5 5 0 Phage MuF-C-terminal domain PAN_1 PF00024.26 RUS72956.1 - 3.7e-05 23.6 0.5 3.7e-05 23.6 0.5 5.2 1 1 2 5 5 5 1 PAN domain Glyco_trans_A_1 PF09318.10 RUS72956.1 - 0.019 14.7 103.2 3.2 7.4 5.2 10.0 2 1 10 12 12 12 0 Glycosyl transferase 1 domain A Myelin_MBP PF01669.17 RUS72956.1 - 0.7 10.5 53.6 1.4e+02 3.0 3.2 10.3 2 1 3 5 5 5 0 Myelin basic protein Thioredoxin_7 PF13899.6 RUS72957.1 - 6.6e-05 23.0 20.9 1.8 8.8 0.2 6.1 2 2 3 6 6 6 3 Thioredoxin-like HAD_SAK_1 PF10307.9 RUS72957.1 - 0.0017 18.2 9.4 1.8 8.3 0.4 4.6 1 1 4 5 5 5 2 HAD domain family 1 in Swiss Army Knife RNA repair proteins Glutaredoxin PF00462.24 RUS72957.1 - 0.008 16.4 22.3 11 6.3 0.1 8.2 3 2 5 8 8 8 1 Glutaredoxin Fibrinogen_BP PF08017.11 RUS72957.1 - 0.009 14.5 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein zf_C2H2_ZHX PF18387.1 RUS72957.1 - 0.011 15.3 18.2 44 3.8 0.1 7.7 1 1 8 9 9 9 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 RUS72957.1 - 0.031 14.5 14.6 19 5.6 0.1 5.4 4 0 0 4 4 4 0 zinc-ribbon DnaJ_CXXCXGXG PF00684.19 RUS72957.1 - 0.13 12.6 24.2 18 5.8 8.6 4.8 1 1 2 3 3 3 0 DnaJ central domain DUF918 PF06033.11 RUS72957.1 - 0.48 10.4 5.7 11 6.0 0.3 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Thump_like PF18096.1 RUS72957.1 - 0.96 9.4 6.8 65 3.6 0.2 5.3 1 1 2 3 3 3 0 THUMP domain-like zf-3CxxC PF13695.6 RUS72957.1 - 1.1 9.7 21.6 12 6.5 3.5 4.4 1 1 2 3 3 3 0 Zinc-binding domain zf_C2HC_14 PF18574.1 RUS72957.1 - 1.8 8.4 12.5 56 3.7 0.2 4.9 4 0 0 4 4 4 0 C2HC Zing finger domain 7TM_GPCR_Srw PF10324.9 RUS72958.1 - 8.8e-11 41.6 26.0 4.4e-06 26.2 2.9 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS72958.1 - 4.2e-08 32.8 15.2 4.2e-08 32.8 15.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS72958.1 - 4.8e-05 23.1 13.5 4.8e-05 23.1 13.5 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2448 PF10476.9 RUS72958.1 - 0.01 15.7 0.4 0.01 15.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) ECSCR PF15820.5 RUS72958.1 - 0.088 12.6 1.1 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Methyltransf_22 PF13383.6 RUS72959.1 - 1.3e-20 74.1 0.4 1.7e-20 73.7 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS72959.1 - 0.033 14.2 0.0 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase FkbM domain FDX-ACB PF03147.14 RUS72959.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain zf-RING_5 PF14634.6 RUS72960.1 - 0.011 15.6 8.5 0.018 15.0 8.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 RUS72960.1 - 0.076 12.9 0.2 0.076 12.9 0.2 2.3 2 1 1 3 3 3 0 Rad50 zinc hook motif Paired_CXXCH_1 PF09699.10 RUS72960.1 - 0.11 12.3 2.7 0.38 10.5 2.7 1.9 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-RING_2 PF13639.6 RUS72960.1 - 0.29 11.5 9.3 0.51 10.7 9.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 RUS72960.1 - 0.5 10.3 8.9 0.91 9.5 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS72960.1 - 7.7 6.5 9.5 16 5.5 9.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Asparaginase_2 PF01112.18 RUS72963.1 - 1.9e-57 194.6 3.1 2.4e-57 194.3 3.1 1.0 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.7 RUS72965.1 - 6.6e-08 33.0 0.0 0.0076 16.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS72965.1 - 1.7e-05 24.8 0.1 36 5.4 0.0 6.1 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 RUS72965.1 - 6.7e-05 23.4 0.1 7.8 7.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS72965.1 - 0.0014 18.9 0.0 7.5 7.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS72965.1 - 0.018 15.5 1.7 34 5.1 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat HABP4_PAI-RBP1 PF04774.15 RUS72966.1 - 7.9e-30 104.1 8.9 7.9e-30 104.1 8.9 3.5 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 RUS72966.1 - 1.2e-11 45.6 21.9 1.2e-11 45.6 21.9 3.3 1 1 1 3 3 3 1 Intracellular hyaluronan-binding protein 4 N-terminal RhlB PF12300.8 RUS72966.1 - 0.009 16.2 7.5 0.009 16.2 7.5 3.6 2 1 1 3 3 3 1 ATP-dependent RNA helicase RhlB zf-H2C2_2 PF13465.6 RUS72967.1 - 1.8e-10 40.7 3.6 1.8e-05 24.9 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS72967.1 - 1.3e-09 38.0 16.9 3.7e-06 27.1 0.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS72967.1 - 1.6e-05 24.8 0.3 4.7e-05 23.3 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS72967.1 - 2.4e-05 24.8 7.3 0.00025 21.6 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-TRAF PF02176.18 RUS72967.1 - 0.004 17.8 2.3 0.004 17.8 2.3 2.7 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C2HE PF16278.5 RUS72967.1 - 0.022 15.2 0.1 0.077 13.5 0.0 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Qua1 PF16274.5 RUS72967.1 - 0.12 12.2 0.1 3.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Qua1 domain zf-met PF12874.7 RUS72967.1 - 0.29 11.6 0.1 0.29 11.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RUS72967.1 - 0.41 10.6 6.4 0.35 10.8 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CRD PF17979.1 RUS72967.1 - 0.49 10.5 8.0 0.99 9.5 8.0 1.5 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions IF-2B PF01008.17 RUS72968.1 - 1.1e-64 218.4 1.0 1.9e-64 217.6 1.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Phage_min_cap2 PF06152.11 RUS72968.1 - 0.014 14.3 0.2 0.018 14.0 0.2 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 GPCR_chapero_1 PF11904.8 RUS72970.1 - 9.1e-65 219.1 0.5 1.3e-64 218.6 0.5 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 RUS72970.1 - 4.8e-12 46.3 0.1 9.6e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS72970.1 - 3.6e-10 39.8 0.9 1.5e-07 31.6 0.7 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RUS72970.1 - 2.4e-09 36.7 0.2 0.00044 20.5 0.3 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS72970.1 - 3.5e-07 30.7 0.1 2.1e-06 28.2 0.0 2.2 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS72970.1 - 4.2e-07 30.1 0.0 9.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ECH_1 PF00378.20 RUS72971.1 - 5.5e-37 127.4 0.0 6.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS72971.1 - 2.9e-23 82.9 0.1 3.6e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 RUS72972.1 - 3.8e-95 319.0 0.0 4.5e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sugar_tr PF00083.24 RUS72973.1 - 6.5e-47 160.4 2.8 7.4e-47 160.2 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS72973.1 - 2e-10 40.1 17.4 2.8e-10 39.6 17.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 RUS72973.1 - 1.5 7.8 10.8 0.45 9.5 7.7 1.6 2 0 0 2 2 2 0 PUCC protein ATP-synt_Z PF16594.5 RUS72973.1 - 3 7.4 7.0 4 7.0 1.1 2.5 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated FAM199X PF15814.5 RUS72974.1 - 0.86 8.6 2.8 1.3 8.0 2.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X N2227 PF07942.12 RUS72975.1 - 5.1e-100 334.1 0.1 7.5e-100 333.6 0.1 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 RUS72975.1 - 5.3e-06 27.0 0.0 0.00028 21.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS72975.1 - 2.5e-05 24.2 0.0 5.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 RUS72975.1 - 0.0003 20.1 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 RUS72975.1 - 0.0014 19.2 0.0 0.8 10.5 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RUS72975.1 - 0.0046 17.7 0.0 0.02 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain 7tm_2 PF00002.24 RUS72976.1 - 3.1e-24 85.6 4.8 2.2e-22 79.5 4.8 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 RUS72976.1 - 0.47 9.5 4.3 0.26 10.4 0.8 1.9 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor GPS PF01825.21 RUS72977.1 - 7.7e-13 48.8 3.0 7.7e-13 48.8 3.0 3.2 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif CUB PF00431.20 RUS72977.1 - 3.4e-10 40.2 1.4 0.00011 22.5 0.0 3.3 4 0 0 4 4 4 2 CUB domain EGF PF00008.27 RUS72977.1 - 3.6e-09 36.8 77.8 0.016 15.5 6.2 8.3 7 0 0 7 7 7 6 EGF-like domain EGF_2 PF07974.13 RUS72977.1 - 4.7e-06 26.9 85.4 0.39 11.1 10.8 7.2 6 0 0 6 6 6 6 EGF-like domain GAIN PF16489.5 RUS72977.1 - 0.00034 20.1 0.3 0.00049 19.6 0.3 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Sgf11 PF08209.11 RUS72977.1 - 0.00038 20.0 2.5 0.69 9.5 0.2 2.8 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) Cry1Ac_D5 PF17997.1 RUS72977.1 - 0.037 13.9 0.3 0.095 12.6 0.3 1.6 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 RNA_pol_Rpb1_R PF05001.13 RUS72977.1 - 4.1 7.9 6.9 38 4.9 0.3 4.2 3 0 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat AAA_lid_7 PF17867.1 RUS72978.1 - 2.2e-14 53.5 7.8 0.22 11.7 0.1 5.1 1 1 4 5 5 5 5 Midasin AAA lid domain DUF3014 PF11219.8 RUS72978.1 - 0.0017 18.6 0.0 16 5.7 0.0 3.0 1 1 0 3 3 3 2 Protein of unknown function (DUF3014) Topo_C_assoc PF14370.6 RUS72978.1 - 0.0041 17.0 3.1 6.1 6.8 0.1 3.1 1 1 4 5 5 5 4 C-terminal topoisomerase domain Sulfotransfer_4 PF17784.1 RUS72978.1 - 0.11 12.3 6.5 1.9 8.3 1.4 2.1 1 1 0 2 2 2 0 Sulfotransferase domain WRW PF10206.9 RUS72978.1 - 0.28 11.6 3.4 14 6.1 0.2 2.2 1 1 1 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Bacteriocin_IIi PF11758.8 RUS72978.1 - 1.3 8.9 13.9 68 3.4 0.1 4.9 1 1 4 5 5 5 0 Aureocin-like type II bacteriocin RVT_1 PF00078.27 RUS72979.1 - 1.2e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) E1_DerP2_DerF2 PF02221.15 RUS72979.1 - 6.6e-05 23.4 0.2 0.00012 22.5 0.2 1.4 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RUS72980.1 - 0.0001 22.7 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 ML domain DHFR_1 PF00186.19 RUS72980.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrofolate reductase DUF2749 PF10907.8 RUS72980.1 - 0.25 11.5 1.6 0.43 10.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Abhydrolase_5 PF12695.7 RUS72981.1 - 8.8e-07 28.8 0.1 6e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family LRR_8 PF13855.6 RUS72983.1 - 7.9e-91 297.8 126.4 1.3e-13 50.5 1.8 13.7 4 3 13 17 17 17 17 Leucine rich repeat LRR_4 PF12799.7 RUS72983.1 - 2.5e-50 167.6 75.9 5e-05 23.6 0.2 15.0 14 1 1 15 15 15 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS72983.1 - 7.3e-32 110.0 3.2 2.2e-07 30.9 0.3 6.7 4 2 2 6 6 6 6 BspA type Leucine rich repeat region (6 copies) TIR_2 PF13676.6 RUS72983.1 - 1.7e-14 54.4 0.0 5.7e-14 52.7 0.0 2.0 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS72983.1 - 2.9e-14 53.3 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 RUS72983.1 - 4.3e-14 52.4 30.3 0.0061 16.1 2.2 7.7 5 3 3 8 8 8 6 Leucine-rich repeat LRR_1 PF00560.33 RUS72983.1 - 1.8e-11 42.9 62.4 0.31 11.8 0.5 18.6 20 0 0 20 20 19 3 Leucine Rich Repeat LRR_6 PF13516.6 RUS72983.1 - 1.1e-05 25.1 63.8 2.7 8.3 0.0 16.9 19 0 0 19 19 18 4 Leucine Rich repeat LRRNT PF01462.18 RUS72983.1 - 0.00042 19.9 9.5 0.003 17.1 0.9 3.3 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain FNIP PF05725.12 RUS72983.1 - 0.00055 20.0 0.0 0.073 13.3 0.4 3.9 3 2 0 3 3 3 1 FNIP Repeat DnaGprimase_HBD PF16730.5 RUS72983.1 - 0.022 14.8 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain NUP214 PF16755.5 RUS72983.1 - 0.81 8.9 6.8 0.34 10.1 1.0 2.6 2 0 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 TED_complement PF07678.14 RUS72984.1 - 1.4e-33 116.2 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 RUS72984.1 - 5.3e-18 65.5 0.1 1.1e-17 64.6 0.1 1.5 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain POX PF07526.11 RUS72984.1 - 0.15 12.6 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Associated with HOX 7tm_1 PF00001.21 RUS72985.1 - 2.9e-36 125.1 18.0 4.1e-36 124.7 18.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 RUS72985.1 - 0.7 9.6 11.8 0.038 13.8 5.6 2.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 TMPIT PF07851.13 RUS72986.1 - 1.4e-73 248.0 16.8 1.7e-73 247.7 16.8 1.1 1 0 0 1 1 1 1 TMPIT-like protein Met_gamma_lyase PF06838.11 RUS72986.1 - 0.21 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Neurensin PF14927.6 RUS72986.1 - 0.3 10.8 3.3 0.17 11.6 1.0 1.7 2 0 0 2 2 2 0 Neurensin Med19 PF10278.9 RUS72987.1 - 3.9e-55 186.5 14.3 4.8e-55 186.2 14.3 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.9 RUS72987.1 - 0.01 15.5 19.4 0.01 15.5 19.4 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein THOC2_N PF16134.5 RUS72987.1 - 2.1 6.9 13.6 2.9 6.4 13.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Presenilin PF01080.17 RUS72987.1 - 2.9 6.5 10.1 3.8 6.2 10.1 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 RUS72987.1 - 3.2 7.9 8.0 4.7 7.3 8.0 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 RUS72987.1 - 6.8 6.4 14.8 9.6 5.9 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF383 PF04063.14 RUS72988.1 - 9.7e-54 181.9 2.9 1.1e-53 181.8 0.1 2.4 3 1 1 4 4 4 1 Domain of unknown function (DUF383) DUF384 PF04064.13 RUS72988.1 - 3.9e-18 65.0 1.1 8.7e-18 63.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF5319 PF17252.2 RUS72988.1 - 0.069 13.4 0.8 5.1 7.3 0.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5319) NESP55 PF06390.12 RUS72988.1 - 0.28 10.7 4.7 0.38 10.3 4.7 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) zf-BED PF02892.15 RUS72989.1 - 1.2e-10 41.2 2.0 2.2e-10 40.4 2.0 1.4 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_3rep PF18868.1 RUS72989.1 - 0.045 14.4 0.2 0.13 13.0 0.1 1.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DRIM PF07539.12 RUS72990.1 - 0.2 9.9 0.2 0.23 9.7 0.2 1.0 1 0 0 1 1 1 0 Down-regulated in metastasis CH PF00307.31 RUS72991.1 - 6.7e-57 190.4 0.1 4e-28 97.8 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Spectrin PF00435.21 RUS72991.1 - 3.4e-47 159.3 14.6 2.8e-20 72.8 4.8 4.4 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 RUS72991.1 - 4e-26 90.9 0.0 1.3e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 RUS72991.1 - 5.3e-09 35.8 0.0 1.4e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.32 RUS72991.1 - 9.1e-08 31.1 0.1 0.0045 16.4 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS72991.1 - 5.1e-06 26.9 0.1 1.8e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS72991.1 - 2.9e-05 23.6 0.2 0.0069 16.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RUS72991.1 - 0.0061 16.4 0.0 0.021 14.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair SpoU_methylase PF00588.19 RUS72993.1 - 7.4e-25 87.8 0.0 2.1e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family Redoxin PF08534.10 RUS72994.1 - 6.4e-26 90.8 0.0 8.5e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RUS72994.1 - 5.8e-14 52.1 0.0 8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family MOZ_SAS PF01853.18 RUS72995.1 - 8.9e-60 201.4 2.2 8.9e-60 201.4 2.2 1.6 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 RUS72995.1 - 9.9e-25 85.9 3.3 2.2e-24 84.8 3.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 RUS72995.1 - 1.2e-17 63.5 0.0 2.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 RUS72995.1 - 0.0088 16.5 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Agenet PF05641.12 RUS72995.1 - 0.093 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Agenet domain DUF2326 PF10088.9 RUS72995.1 - 0.096 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Acetyltransf_1 PF00583.25 RUS72995.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.6 RUS72995.1 - 0.72 10.9 2.7 2.1 9.4 2.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Proteasome PF00227.26 RUS72997.1 - 8.8e-54 181.9 1.1 1.1e-53 181.5 1.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS72997.1 - 1.3e-13 50.4 0.1 2.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_A_bac PF01000.26 RUS72997.1 - 0.041 14.3 0.2 0.073 13.4 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain SGTA_dimer PF16546.5 RUS72997.1 - 0.049 13.4 0.8 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 Homodimerisation domain of SGTA KBP_C PF12309.8 RUS72998.1 - 4.8e-110 368.4 9.0 4.8e-110 368.4 9.0 2.0 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_7 PF13176.6 RUS72998.1 - 0.00096 19.0 2.4 0.016 15.2 0.1 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS72998.1 - 0.0014 18.9 7.3 0.074 13.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS72998.1 - 0.0046 16.8 0.6 0.037 13.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS72998.1 - 0.0073 16.1 3.4 0.13 12.1 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS72998.1 - 0.17 12.1 8.8 0.44 10.8 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DLIC PF05783.11 RUS72999.1 - 1.9e-11 43.5 0.2 1.6e-06 27.2 0.1 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 RUS72999.1 - 3.7e-05 23.9 0.0 0.00011 22.3 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RNase_J_C PF17770.1 RUS72999.1 - 0.0016 19.5 0.2 0.0033 18.4 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain Ras PF00071.22 RUS72999.1 - 0.0044 16.6 0.0 0.74 9.4 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.6 RUS72999.1 - 0.013 15.9 0.1 0.052 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF2229 PF09989.9 RUS72999.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Gtr1_RagA PF04670.12 RUS72999.1 - 0.036 13.4 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 RUS72999.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 RUS72999.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS72999.1 - 0.14 11.9 0.2 1.1 8.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain Tyr-DNA_phospho PF06087.12 RUS73000.1 - 1.1e-124 416.5 0.0 1.5e-124 416.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 RUS73000.1 - 8e-11 41.7 3.5 8e-11 41.7 3.5 1.9 2 0 0 2 2 2 1 PBZ domain 7tm_1 PF00001.21 RUS73001.1 - 1.5e-24 86.7 5.6 1.5e-24 86.7 5.6 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS73001.1 - 7e-06 25.6 5.8 1.1e-05 25.0 5.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS73001.1 - 3.3e-05 23.7 12.2 5.5e-05 22.9 12.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS73001.1 - 0.019 14.3 10.6 0.03 13.6 10.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Git3 PF11710.8 RUS73001.1 - 0.12 12.1 9.3 0.21 11.3 9.3 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 SDA1 PF05285.12 RUS73002.1 - 9.5e-06 25.3 101.0 3.6e-05 23.4 37.5 2.3 2 0 0 2 2 2 2 SDA1 Caldesmon PF02029.15 RUS73002.1 - 1.5e-05 24.0 29.2 1.9e-05 23.7 29.2 1.3 1 0 0 1 1 1 1 Caldesmon CCSAP PF15748.5 RUS73002.1 - 0.0062 16.8 17.5 0.012 15.9 17.5 1.4 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated BUD22 PF09073.10 RUS73002.1 - 0.011 15.1 37.7 0.011 15.1 37.7 2.1 2 0 0 2 2 2 0 BUD22 DUF4045 PF13254.6 RUS73002.1 - 0.012 15.3 14.5 0.016 14.9 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 RUS73002.1 - 0.081 11.7 24.1 0.0099 14.7 18.6 1.8 2 0 0 2 2 2 0 Presenilin Velvet PF11754.8 RUS73002.1 - 0.21 11.5 3.2 0.11 12.4 0.8 1.6 1 1 1 2 2 2 0 Velvet factor NARP1 PF12569.8 RUS73002.1 - 0.23 10.3 20.9 0.58 9.0 20.9 1.7 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.9 RUS73002.1 - 0.24 11.0 42.2 0.53 9.9 42.2 1.6 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.7 RUS73002.1 - 0.25 9.4 14.4 0.32 9.1 14.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC53 PF10152.9 RUS73002.1 - 0.33 11.4 17.7 0.67 10.4 17.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CSG2 PF16965.5 RUS73002.1 - 0.39 9.6 2.6 0.69 8.8 2.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator PA26 PF04636.13 RUS73002.1 - 1.2 8.0 13.4 1.4 7.7 13.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Endostatin PF06482.11 RUS73002.1 - 1.2 8.5 5.3 1.7 8.1 5.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FGF-BP1 PF06473.12 RUS73002.1 - 1.3 8.8 17.8 2.1 8.1 17.8 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ALMT PF11744.8 RUS73002.1 - 1.7 7.4 11.1 2.3 7.0 11.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 RUS73002.1 - 2.7 6.9 6.3 3.3 6.7 6.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Gti1_Pac2 PF09729.9 RUS73002.1 - 2.9 7.9 13.3 7.2 6.7 11.7 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family MCM_bind PF09739.9 RUS73002.1 - 3.3 6.0 17.0 7 5.0 17.0 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Neur_chan_memb PF02932.16 RUS73002.1 - 3.8 7.5 7.2 5.1 7.1 7.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.6 RUS73002.1 - 3.9 7.6 13.1 5.5 7.1 13.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RP-C_C PF11800.8 RUS73002.1 - 7 6.7 14.3 11 6.1 14.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Connexin PF00029.19 RUS73002.1 - 7.2 6.3 24.1 9.3e+02 -0.6 24.7 2.6 2 1 0 2 2 2 0 Connexin AAA_11 PF13086.6 RUS73002.1 - 8.4 6.1 16.1 12 5.5 16.1 1.2 1 0 0 1 1 1 0 AAA domain Smg8_Smg9 PF10220.9 RUS73002.1 - 9.2 4.4 16.3 14 3.8 16.3 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Sec62 PF03839.16 RUS73002.1 - 9.3 5.7 17.0 18 4.7 17.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SID-1_RNA_chan PF13965.6 RUS73002.1 - 9.6 4.5 8.6 20 3.4 8.6 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UBA PF00627.31 RUS73003.1 - 0.054 13.4 0.0 12 5.9 0.0 3.3 2 1 1 3 3 3 0 UBA/TS-N domain UBA_3 PF09288.10 RUS73003.1 - 0.087 12.6 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain IHABP4_N PF16174.5 RUS73003.1 - 0.16 12.5 3.0 2.3 8.8 0.1 2.8 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF2464 PF10240.9 RUS73003.1 - 0.88 9.1 8.3 1 8.9 0.0 3.0 3 1 0 3 3 3 0 Multivesicular body subunit 12 DUF1378 PF07125.11 RUS73004.1 - 0.056 13.6 1.7 0.16 12.1 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) 7tm_1 PF00001.21 RUS73005.1 - 1.1e-10 41.3 19.6 1.7e-10 40.7 19.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS73005.1 - 8.5e-07 28.5 15.3 8.5e-07 28.5 15.3 2.3 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw GLE1 PF07817.13 RUS73005.1 - 0.072 12.3 1.2 0.11 11.7 1.2 1.3 1 0 0 1 1 1 0 GLE1-like protein CytochromB561_N PF09786.9 RUS73005.1 - 3.3 6.6 8.1 0.77 8.7 0.5 2.3 2 0 0 2 2 2 0 Cytochrome B561, N terminal Alpha-amylase PF00128.24 RUS73006.1 - 2.1e-91 307.0 0.1 4e-91 306.1 0.1 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 RUS73006.1 - 0.0003 21.2 0.0 0.049 14.1 0.0 2.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 RUS73006.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain HMA PF00403.26 RUS73007.1 - 6.9e-56 186.6 1.3 6.6e-14 52.1 0.1 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 RUS73007.1 - 1e-51 176.3 0.3 1.9e-51 175.3 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RUS73007.1 - 9.8e-46 155.6 2.6 9.8e-46 155.6 2.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RUS73007.1 - 1.1e-05 25.4 6.6 9.3e-05 22.3 1.1 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase YbaB_DNA_bd PF02575.16 RUS73007.1 - 0.0012 19.0 0.4 2.8 8.2 0.0 2.9 3 0 0 3 3 2 2 YbaB/EbfC DNA-binding family HAD PF12710.7 RUS73007.1 - 0.094 13.1 0.0 0.34 11.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 RUS73007.1 - 0.15 12.2 0.1 0.81 9.8 0.1 2.4 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DHHC PF01529.20 RUS73007.1 - 0.55 10.3 1.9 1.9 8.6 0.1 2.6 2 1 0 2 2 2 0 DHHC palmitoyltransferase Endonuclease_7 PF02945.15 RUS73007.1 - 0.7 9.9 3.0 29 4.7 0.1 3.5 4 0 0 4 4 4 0 Recombination endonuclease VII zf-LITAF-like PF10601.9 RUS73007.1 - 3.7 7.9 6.5 68 3.8 0.1 4.2 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Fer2_BFD PF04324.15 RUS73007.1 - 4.3 7.8 8.9 43 4.5 0.1 4.5 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain protein_MS5 PF04776.12 RUS73008.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein MS5 Ion_trans_2 PF07885.16 RUS73009.1 - 8.8e-20 70.5 14.8 1.5e-13 50.5 8.6 2.6 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.31 RUS73009.1 - 0.0043 16.3 1.8 0.0066 15.7 1.8 1.3 1 0 0 1 1 1 1 Ion transport protein KxDL PF10241.9 RUS73009.1 - 0.012 15.9 1.3 0.019 15.2 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4862 PF16154.5 RUS73009.1 - 0.032 13.6 0.2 0.047 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) DNA_pol_phi PF04931.13 RUS73010.1 - 1.3e-38 132.6 8.5 4.9e-38 130.8 8.5 1.7 1 1 0 1 1 1 1 DNA polymerase phi B9-C2 PF07162.11 RUS73011.1 - 9.6e-45 152.8 0.2 1.4e-44 152.3 0.2 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Rogdi_lz PF10259.9 RUS73012.1 - 3.9e-29 101.9 2.9 1.2e-26 93.8 0.9 2.0 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein IU_nuc_hydro PF01156.19 RUS73013.1 - 4.7e-05 23.1 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 RUS73014.1 - 2.3e-61 208.1 0.1 3.5e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FAR1 PF03101.15 RUS73014.1 - 0.16 12.7 0.1 0.31 11.7 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain MFS_1 PF07690.16 RUS73015.1 - 5.6e-39 134.0 25.7 3.2e-38 131.6 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS73015.1 - 2.2e-12 46.3 19.0 1.1e-07 30.8 0.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 RUS73015.1 - 3.9e-10 38.6 21.2 0.00012 20.6 1.4 4.1 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 RUS73015.1 - 3.2e-09 36.2 7.9 3.2e-09 36.2 7.9 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 RUS73015.1 - 0.076 13.1 0.0 0.076 13.1 0.0 4.2 4 1 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III RasGAP PF00616.19 RUS73016.1 - 4e-29 101.8 1.9 4.3e-26 91.9 0.2 3.3 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 RUS73016.1 - 9.6e-21 74.4 0.5 4.9e-20 72.1 0.5 2.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 RUS73016.1 - 0.00016 21.6 1.1 0.0039 17.1 0.1 3.6 3 0 0 3 3 3 1 Cell morphogenesis C-terminal CRAL_TRIO PF00650.20 RUS73016.1 - 0.00031 20.5 2.6 0.00075 19.3 0.6 2.8 2 0 0 2 2 2 1 CRAL/TRIO domain TRP PF06011.12 RUS73017.1 - 0.013 14.3 0.1 0.014 14.1 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ribosomal_L16 PF00252.18 RUS73020.1 - 3e-23 82.3 0.0 4.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.32 RUS73021.1 - 3e-11 43.7 1.8 6.9e-05 23.5 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat bVLRF1 PF18826.1 RUS73022.1 - 2.3e-56 189.8 0.2 6.3e-56 188.4 0.2 1.8 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 RUS73022.1 - 1.4e-13 50.4 1.0 1.4e-13 50.4 1.0 3.0 3 0 0 3 3 3 1 Vms1-associating treble clef domain Ank_5 PF13857.6 RUS73022.1 - 4.6e-07 30.0 0.1 1.1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS73022.1 - 2e-06 28.3 0.0 6.5e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS73022.1 - 3.8e-06 27.1 0.2 1.1e-05 25.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 RUS73022.1 - 0.00016 21.8 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RUS73022.1 - 0.003 18.1 0.0 0.0097 16.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) baeRF_family10 PF18854.1 RUS73022.1 - 0.027 14.7 0.6 0.027 14.7 0.6 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 zf-FCS PF06467.14 RUS73022.1 - 0.14 12.1 4.4 0.12 12.3 0.6 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DRY_EERY PF09750.9 RUS73022.1 - 3.9 7.7 11.5 0.14 12.4 4.0 2.6 2 0 0 2 2 2 0 Alternative splicing regulator DNA_pol_B_palm PF14792.6 RUS73023.1 - 4.4e-38 130.0 0.0 1e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 RUS73023.1 - 6.4e-21 74.3 0.0 1.4e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 RUS73023.1 - 1.4e-19 70.2 0.2 5.2e-19 68.4 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 RUS73023.1 - 1.5e-19 69.5 0.2 4.4e-19 68.1 0.2 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 RUS73023.1 - 1.4e-05 25.4 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 RUS73023.1 - 0.023 14.9 0.0 5.9 7.2 0.0 2.7 1 1 1 2 2 2 0 Pathogenicity locus NTP_transf_2 PF01909.23 RUS73023.1 - 0.046 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF5440 PF17509.2 RUS73024.1 - 0.0022 17.5 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5440) HATPase_c_4 PF13749.6 RUS73024.1 - 0.027 14.6 0.1 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal Pkinase PF00069.25 RUS73025.1 - 2.7e-63 213.8 0.0 2.7e-63 213.8 0.0 3.9 3 1 1 4 4 4 1 Protein kinase domain PKK PF12474.8 RUS73025.1 - 2.7e-54 183.1 94.4 1.1e-30 106.5 39.8 5.3 3 2 1 5 5 5 2 Polo kinase kinase Pkinase_Tyr PF07714.17 RUS73025.1 - 1.8e-47 161.8 0.0 1.8e-47 161.8 0.0 3.5 4 0 0 4 4 4 1 Protein tyrosine kinase IMPa_helical PF18642.1 RUS73025.1 - 0.045 14.2 0.6 0.045 14.2 0.6 3.1 3 0 0 3 3 3 0 Immunomodulating metalloprotease helical domain Phage_Coat_A PF05357.13 RUS73027.1 - 0.062 13.1 12.9 58 3.6 0.3 6.6 1 1 5 6 6 6 0 Phage Coat Protein A CBM_48 PF02922.18 RUS73028.1 - 2.8e-09 37.2 12.0 3.3 8.1 0.3 6.3 1 1 7 8 8 8 7 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF5119 PF17145.4 RUS73028.1 - 2.5e-05 24.3 19.3 1.2 9.0 0.5 4.9 1 1 4 5 5 5 5 Domain of unknown function (DUF5119) DBB PF14545.6 RUS73028.1 - 6.4e-05 22.9 17.0 0.26 11.2 2.5 3.4 1 1 2 3 3 3 3 Dof, BCAP, and BANK (DBB) motif, PAD_N PF08526.10 RUS73028.1 - 0.00024 21.4 34.0 0.84 10.0 3.1 5.6 1 1 6 7 7 7 7 Protein-arginine deiminase (PAD) N-terminal domain Glyco_hydro_2 PF00703.21 RUS73028.1 - 0.0018 18.9 25.3 4 8.1 1.5 4.9 1 1 3 4 4 4 3 Glycosyl hydrolases family 2 CNRIP1 PF15043.6 RUS73028.1 - 0.011 15.3 35.2 1.2 8.7 11.5 5.0 1 1 2 3 3 3 0 CB1 cannabinoid receptor-interacting protein 1 Pyocin_S PF06958.12 RUS73028.1 - 0.23 12.0 20.5 3.5 8.2 3.5 3.4 1 1 2 3 3 3 0 S-type Pyocin CBM_4_9 PF02018.17 RUS73028.1 - 0.33 11.2 46.3 1.8 8.9 3.1 4.6 1 1 2 4 4 4 0 Carbohydrate binding domain DUF4436 PF14494.6 RUS73028.1 - 0.41 9.9 31.0 0.84 8.9 4.0 4.8 1 1 2 4 4 4 0 Domain of unknown function (DUF4436) Big_3_5 PF16640.5 RUS73028.1 - 0.99 9.6 38.4 24 5.2 0.8 5.6 1 1 2 4 4 4 0 Bacterial Ig-like domain (group 3) CBM46 PF18448.1 RUS73028.1 - 4.6 7.6 32.0 22 5.4 2.9 5.7 1 1 9 10 10 10 0 Carbohydrate binding domain GP46 PF07409.12 RUS73028.1 - 4.7 7.0 24.3 13 5.6 2.0 5.2 1 1 6 7 7 7 0 Phage protein GP46 AbiEii PF08843.11 RUS73028.1 - 5.6 6.8 6.0 4.3e+02 0.7 6.0 3.1 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Ank_2 PF12796.7 RUS73029.1 - 4.7e-05 23.9 0.0 0.00021 21.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS73029.1 - 0.00016 22.1 0.0 0.09 13.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS73029.1 - 0.00054 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS73029.1 - 0.0027 18.1 0.0 2.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat PRODH PF18327.1 RUS73030.1 - 0.042 14.1 31.8 45 4.4 0.3 10.0 1 1 11 12 12 12 0 Proline utilization A proline dehydrogenase N-terminal domain Y_Y_Y PF07495.13 RUS73031.1 - 0.0049 16.8 3.3 3.9 7.5 0.1 3.8 1 1 3 4 4 4 4 Y_Y_Y domain ParE_toxin PF05016.15 RUS73031.1 - 0.022 15.4 1.7 0.024 15.2 0.7 1.7 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE DivIC PF04977.15 RUS73031.1 - 1.1 9.0 10.5 0.25 11.1 6.5 2.1 1 1 1 2 2 2 0 Septum formation initiator Tropomyosin_1 PF12718.7 RUS73031.1 - 5.8 7.1 25.3 4.7 7.4 18.7 2.2 1 1 1 2 2 2 0 Tropomyosin like KASH_CCD PF14662.6 RUS73032.1 - 0.0047 16.8 16.0 0.0098 15.7 16.0 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 RUS73032.1 - 0.0055 16.9 6.8 0.0055 16.9 6.8 2.5 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 RUS73032.1 - 0.0061 16.2 18.7 0.22 11.2 5.1 3.4 3 1 1 4 4 4 3 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 RUS73032.1 - 0.054 13.7 14.1 0.25 11.6 3.6 4.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper CENP-K PF11802.8 RUS73032.1 - 0.058 13.0 10.2 0.063 12.8 9.3 1.6 1 1 0 1 1 1 0 Centromere-associated protein K CheZ PF04344.13 RUS73032.1 - 0.068 13.1 6.3 0.028 14.3 3.2 1.7 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ HPPK PF01288.20 RUS73032.1 - 0.09 13.3 4.2 0.37 11.3 0.7 2.3 1 1 1 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Ax_dynein_light PF10211.9 RUS73032.1 - 0.1 12.6 13.8 0.073 13.0 6.8 2.6 1 1 0 2 2 2 0 Axonemal dynein light chain Sas6_CC PF18594.1 RUS73032.1 - 0.11 12.3 0.6 0.11 12.3 0.6 4.0 5 0 0 5 5 5 0 Sas6/XLF/XRCC4 coiled-coil domain Spc7 PF08317.11 RUS73032.1 - 0.16 10.8 15.5 0.13 11.1 12.3 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 RUS73032.1 - 0.41 10.9 15.6 0.79 10.0 3.4 3.2 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 RUS73032.1 - 0.83 10.6 14.9 0.1 13.5 7.4 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 RUS73032.1 - 1.1 9.7 19.2 8.1 7.0 12.6 3.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 RUS73032.1 - 1.8 8.8 12.3 0.88 9.9 8.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 RUS73032.1 - 2 8.4 7.4 2.4 8.2 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 RUS73032.1 - 2.3 8.9 12.3 2.3 8.9 2.6 3.0 1 1 2 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 RUS73032.1 - 2.4 8.6 8.0 3.8 8.0 0.5 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 RUS73032.1 - 3.3 8.2 13.5 5.9 7.4 0.5 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 RUS73032.1 - 7.3 5.8 7.9 9.3 5.5 7.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SNase PF00565.17 RUS73033.1 - 0.002 18.6 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF2695 PF10905.8 RUS73033.1 - 0.04 14.1 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Carb_anhydrase PF00194.21 RUS73034.1 - 1.9e-58 198.0 0.1 2.2e-58 197.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ASC PF00858.24 RUS73035.1 - 1.8e-43 149.2 0.4 1.8e-43 149.2 0.4 1.6 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel CNDH2_C PF16858.5 RUS73035.1 - 1.6 8.5 9.8 2.5 7.9 9.8 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CD36 PF01130.21 RUS73036.1 - 7.9e-75 252.2 1.3 3.8e-38 131.2 0.0 2.1 2 0 0 2 2 2 2 CD36 family UPF0223 PF05256.12 RUS73036.1 - 0.00019 21.7 7.4 12 6.3 0.1 4.6 1 1 3 4 4 4 3 Uncharacterised protein family (UPF0223) BTB_3 PF16017.5 RUS73036.1 - 0.0068 16.5 4.7 34 4.6 0.1 5.0 1 1 3 4 4 4 0 BTB/POZ domain Glypican PF01153.19 RUS73036.1 - 0.088 11.6 12.8 22 3.7 1.9 5.1 1 1 4 5 5 5 0 Glypican Phi-29_GP16_7 PF06720.11 RUS73036.1 - 0.12 12.2 1.9 60 3.5 0.0 4.0 1 1 6 7 7 7 0 Bacteriophage phi-29 early protein GP16.7 KAR9 PF08580.10 RUS73036.1 - 3.3 6.1 7.1 4.8 5.6 7.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 P3A PF08727.11 RUS73037.1 - 0.27 10.6 18.5 11 5.5 0.4 5.5 3 2 3 6 6 6 0 Poliovirus 3A protein like Rotavirus_VP1 PF12289.8 RUS73038.1 - 0.00026 20.1 0.1 16 4.4 0.0 4.0 1 1 2 5 5 5 4 Rotavirus VP1 C-terminal domain EpCAM_N PF18635.1 RUS73038.1 - 0.0067 16.6 12.6 1.5e+02 2.7 0.2 7.2 1 1 7 8 8 8 0 Epithelial cell adhesion molecule N-terminal domain DUF1722 PF08349.11 RUS73038.1 - 0.29 11.4 12.4 46 4.3 0.1 4.5 1 1 7 8 8 8 0 Protein of unknown function (DUF1722) PG_binding_1 PF01471.18 RUS73038.1 - 0.31 11.3 7.6 2.4e+03 -1.2 7.6 5.2 1 1 0 1 1 1 0 Putative peptidoglycan binding domain BA14K PF07886.11 RUS73038.1 - 1.1 9.2 20.4 1.8e+02 2.1 0.1 7.5 8 0 0 8 8 8 0 BA14K-like protein MORN PF02493.20 RUS73039.1 - 1.6e-18 65.4 19.0 1.5e-08 34.0 1.7 5.3 6 0 0 6 6 6 4 MORN repeat Cas1_AcylT PF07779.12 RUS73040.1 - 4.6e-54 184.1 18.2 5.6e-54 183.8 18.2 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Acyl_transf_3 PF01757.22 RUS73040.1 - 5.6e-05 22.4 22.9 5.6e-05 22.4 22.9 1.6 2 0 0 2 2 2 1 Acyltransferase family DUF384 PF04064.13 RUS73040.1 - 0.1 12.4 0.1 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF384) Somatomedin_B PF01033.17 RUS73041.1 - 2e-10 40.9 19.5 1.2e-07 32.1 8.9 2.8 2 0 0 2 2 2 2 Somatomedin B domain DDE_Tnp_IS1595 PF12762.7 RUS73042.1 - 1.7e-07 31.3 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 2 ISXO2-like transposase domain DDE_Tnp_1_7 PF13843.6 RUS73043.1 - 0.0047 16.3 0.4 0.0083 15.5 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 DDE_Tnp_ISAZ013 PF07592.11 RUS73043.1 - 0.0081 15.2 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain Cadherin PF00028.17 RUS73045.1 - 0.072 13.5 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Cadherin domain Mito_fiss_reg PF05308.11 RUS73046.1 - 7.2 6.6 12.0 8.2 6.4 12.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Cadherin PF00028.17 RUS73048.1 - 2.1e-05 24.8 0.1 0.016 15.7 0.1 2.4 2 0 0 2 2 2 2 Cadherin domain Tubulin PF00091.25 RUS73049.1 - 6.2e-52 176.7 0.0 1.6e-34 119.8 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS73049.1 - 1.9e-29 102.3 0.0 3.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 RUS73049.1 - 0.0041 16.3 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like NHL PF01436.21 RUS73050.1 - 4.5e-21 73.8 7.7 8.6e-10 38.2 0.4 5.1 4 0 0 4 4 4 3 NHL repeat zf-C3HC4 PF00097.25 RUS73050.1 - 3.8e-08 33.1 5.4 8.5e-08 32.0 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS73050.1 - 4.2e-07 29.9 9.2 1.1e-06 28.5 9.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS73050.1 - 5.3e-06 26.2 6.2 5.4e-06 26.2 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS73050.1 - 7.4e-06 25.8 6.4 1.6e-05 24.8 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS73050.1 - 1e-05 25.8 6.4 2.2e-05 24.7 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain DUF5128 PF17170.4 RUS73050.1 - 2.3e-05 23.7 1.4 0.0052 16.0 0.1 3.5 2 1 1 3 3 3 2 6-bladed beta-propeller SGL PF08450.12 RUS73050.1 - 5.1e-05 23.0 0.1 0.0068 16.0 0.0 2.8 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_4 PF15227.6 RUS73050.1 - 0.00024 21.2 9.1 0.00065 19.8 9.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS73050.1 - 0.0024 17.7 8.7 0.011 15.5 8.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phytase-like PF13449.6 RUS73050.1 - 0.0037 17.2 0.0 1.4 8.8 0.0 2.9 2 1 1 3 3 3 1 Esterase-like activity of phytase Prok-RING_4 PF14447.6 RUS73050.1 - 0.0056 16.5 7.1 0.018 14.9 7.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF839 PF05787.13 RUS73050.1 - 0.15 11.2 2.0 0.17 11.0 0.0 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF839) zf-RING_6 PF14835.6 RUS73050.1 - 0.23 11.4 2.7 0.68 9.8 2.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 RUS73050.1 - 2.7 7.8 7.3 6.9 6.5 7.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger COPIIcoated_ERV PF07970.12 RUS73051.1 - 5.6e-93 310.8 3.1 7.1e-93 310.5 3.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RUS73051.1 - 4.6e-31 107.0 0.1 1.4e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Romo1 PF10247.9 RUS73052.1 - 1.1e-27 96.2 16.4 1.2e-27 96.0 16.4 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 RUS73052.1 - 0.0013 19.1 7.3 0.0015 18.9 7.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1242 PF06842.12 RUS73052.1 - 0.099 12.5 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) RDD PF06271.12 RUS73053.1 - 2.7e-10 40.6 6.1 3.7e-09 36.9 6.1 2.1 1 1 0 1 1 1 1 RDD family HxlR PF01638.17 RUS73054.1 - 0.098 12.5 0.3 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Methyltransf_25 PF13649.6 RUS73055.1 - 3.7e-10 40.4 0.0 4.9e-09 36.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS73055.1 - 1.8e-08 34.9 0.0 7.8e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RUS73055.1 - 5.6e-08 32.5 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RUS73055.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS73055.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 RUS73055.1 - 1.3e-05 25.0 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 RUS73055.1 - 1.4e-05 25.0 0.0 0.00091 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 RUS73055.1 - 7.8e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 RUS73055.1 - 8.6e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 RUS73055.1 - 0.00054 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 RUS73055.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 RUS73055.1 - 0.0066 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 RUS73055.1 - 0.015 15.3 0.4 0.061 13.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.6 RUS73055.1 - 0.018 16.1 0.0 0.081 14.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 RUS73055.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 RUS73055.1 - 0.047 14.4 0.0 0.27 12.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 RUS73055.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Adeno_E3_CR2 PF02439.15 RUS73056.1 - 0.39 10.5 7.2 0.84 9.5 7.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SSB PF00436.25 RUS73057.1 - 1.3e-20 73.4 0.0 1.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family zf-C2H2_4 PF13894.6 RUS73058.1 - 2.2e-37 124.5 153.2 0.0013 19.4 1.7 19.7 19 0 0 19 19 19 17 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS73058.1 - 5.8e-26 89.5 164.3 8.3e-06 26.0 1.9 19.2 19 0 0 19 19 19 14 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73058.1 - 1.7e-21 75.6 130.4 7.8e-05 22.9 0.5 19.2 21 0 0 21 21 21 9 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS73058.1 - 4.8e-10 39.5 91.7 0.0039 17.4 0.2 16.2 16 0 0 16 16 16 11 Zinc-finger double-stranded RNA-binding Thioredoxin_4 PF13462.6 RUS73058.1 - 0.016 15.4 0.3 0.2 11.8 0.0 3.1 1 1 1 2 2 2 0 Thioredoxin zf-C2H2_2 PF12756.7 RUS73058.1 - 0.051 13.9 110.4 0.13 12.6 0.4 15.5 3 2 7 12 12 12 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 RUS73058.1 - 0.25 12.0 75.0 1.4 9.6 5.9 10.6 3 2 6 10 10 10 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 RUS73058.1 - 1.1 9.8 0.0 0.1 13.0 0.4 15.9 17 0 0 17 17 17 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS73058.1 - 2.3 8.3 102.8 0.23 11.5 3.6 15.4 15 0 0 15 15 15 0 C2H2-type zinc finger WW PF00397.26 RUS73059.1 - 6.8e-15 54.9 0.8 1.3e-06 28.3 0.2 2.8 2 0 0 2 2 2 2 WW domain PH PF00169.29 RUS73059.1 - 1.9e-12 47.6 0.2 3e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS73059.1 - 2.5e-05 24.7 0.4 0.00014 22.2 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 RUS73059.1 - 0.023 15.1 2.4 0.22 11.9 0.2 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PH_15 PF17339.2 RUS73059.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 PH domain Lge1 PF11488.8 RUS73061.1 - 0.0035 17.5 1.9 0.0035 17.5 1.9 2.7 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 DUF5082 PF16888.5 RUS73061.1 - 1.8 8.9 17.2 21 5.4 0.7 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 RUS73061.1 - 4.8 7.0 28.1 0.039 13.7 2.7 4.3 4 1 0 4 4 4 0 Septum formation initiator DUF4200 PF13863.6 RUS73061.1 - 6.1 7.3 28.2 0.78 10.2 8.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF3470 PF11953.8 RUS73062.1 - 0.062 13.3 0.8 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) CENP-H PF05837.12 RUS73062.1 - 1 9.8 8.3 0.27 11.7 4.9 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SET PF00856.28 RUS73063.1 - 3.3e-14 53.6 0.4 1.3e-13 51.7 0.0 2.1 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.17 RUS73063.1 - 2.6e-11 42.7 5.8 2.6e-06 27.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73063.1 - 3.8e-08 32.8 8.3 1.5e-05 24.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS73063.1 - 4e-05 23.8 0.6 0.094 13.0 0.2 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS73063.1 - 7.7e-05 23.1 0.9 0.03 15.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS73063.1 - 0.00019 21.4 5.7 1.1 9.7 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS73063.1 - 0.001 19.7 0.0 0.0044 17.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-MYND PF01753.18 RUS73063.1 - 0.0012 18.9 12.1 0.0012 18.9 12.1 3.9 2 1 0 2 2 1 1 MYND finger ANAPC3 PF12895.7 RUS73063.1 - 0.0067 16.6 7.9 0.51 10.6 0.7 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 RUS73063.1 - 0.049 13.6 0.1 0.19 11.7 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS73063.1 - 0.077 13.1 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 MobL PF18555.1 RUS73063.1 - 0.078 12.2 2.8 0.12 11.6 2.8 1.2 1 0 0 1 1 1 0 MobL relaxases TPR_11 PF13414.6 RUS73063.1 - 0.078 12.7 0.4 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 TPR repeat Coronavirus_5 PF05528.11 RUS73063.1 - 8.2 6.5 6.9 17 5.5 3.1 3.0 3 0 0 3 3 2 0 Coronavirus gene 5 protein CD225 PF04505.12 RUS73064.1 - 9.4e-18 64.1 2.6 1.4e-17 63.5 2.6 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein AA_permease_2 PF13520.6 RUS73064.1 - 0.0025 16.7 1.4 0.0031 16.4 1.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4064 PF13273.6 RUS73064.1 - 0.028 14.7 4.0 0.094 13.0 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TMEM107 PF14995.6 RUS73064.1 - 0.044 14.2 0.7 0.06 13.8 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Phage_holin_5_2 PF16079.5 RUS73064.1 - 0.1 12.9 4.2 0.21 12.0 4.2 1.5 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DUF5408 PF17402.2 RUS73064.1 - 0.25 11.3 6.5 0.16 11.9 2.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF4190 PF13828.6 RUS73064.1 - 0.88 9.4 10.9 4.5 7.1 10.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) FAM75 PF14650.6 RUS73064.1 - 8 5.9 8.3 9.9 5.6 8.3 1.1 1 0 0 1 1 1 0 FAM75 family Cadherin_C_2 PF16492.5 RUS73065.1 - 0.077 13.8 1.5 0.58 11.0 0.0 3.0 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Myb_DNA-binding PF00249.31 RUS73066.1 - 6.6e-43 144.7 12.6 2.5e-18 66.0 0.5 3.0 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS73066.1 - 8e-36 122.1 12.8 6.8e-18 64.7 2.1 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RUS73066.1 - 4.2e-08 33.0 0.6 6.7e-05 22.7 0.1 2.9 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 RUS73066.1 - 0.00015 21.9 0.5 0.25 11.6 0.2 2.3 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 RUS73066.1 - 0.0037 17.6 9.1 0.86 10.0 0.7 3.8 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 RUS73066.1 - 0.0068 16.5 0.1 0.0097 16.0 0.1 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) SLIDE PF09111.10 RUS73066.1 - 0.011 15.8 0.1 1.7 8.7 0.0 2.2 1 1 1 2 2 2 0 SLIDE Sigma70_r4_2 PF08281.12 RUS73066.1 - 0.015 14.9 0.0 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase_Tyr PF07714.17 RUS73067.1 - 2.8e-82 275.9 0.0 3.5e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS73067.1 - 9.9e-37 126.7 0.0 1.3e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RUS73067.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS73067.1 - 0.038 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RUS73067.1 - 0.089 12.7 0.4 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family SRA1 PF07304.11 RUS73068.1 - 1.5e-26 92.9 2.1 1.5e-26 92.9 2.1 1.8 1 1 1 2 2 2 1 Steroid receptor RNA activator (SRA1) SOAR PF16533.5 RUS73069.1 - 1.9e-36 124.0 1.5 1.9e-36 124.0 1.5 2.0 2 0 0 2 2 2 1 STIM1 Orai1-activating region SAM_2 PF07647.17 RUS73069.1 - 3.2e-10 40.0 0.1 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS73069.1 - 1.2e-09 38.5 0.0 2.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CENP-H PF05837.12 RUS73069.1 - 2.8 8.4 8.2 0.82 10.1 3.9 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) MeaB PF03308.16 RUS73070.1 - 2.6e-88 295.5 0.0 3.4e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RUS73070.1 - 3e-05 23.7 0.0 8.5e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 RUS73070.1 - 0.00016 21.5 0.1 0.00032 20.6 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 RUS73070.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RUS73070.1 - 0.0079 16.7 0.2 0.021 15.3 0.1 1.7 2 0 0 2 2 2 1 ABC transporter Thymidylate_kin PF02223.17 RUS73070.1 - 0.0083 15.8 0.0 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 RUS73070.1 - 0.011 16.3 0.4 0.054 14.0 0.1 2.3 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 RUS73070.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 RUS73070.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 RUS73070.1 - 0.029 14.5 0.1 0.8 9.8 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS73070.1 - 0.031 14.6 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS73070.1 - 0.036 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 RUS73070.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 RUS73070.1 - 0.041 13.5 0.3 0.43 10.2 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 RUS73070.1 - 0.048 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 RUS73070.1 - 0.071 12.5 2.3 0.28 10.6 1.5 2.2 2 1 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase CLP1_P PF16575.5 RUS73070.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 RUS73070.1 - 0.15 12.5 0.1 1.1 9.7 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_29 PF13555.6 RUS73070.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.6 RUS73070.1 - 0.2 11.5 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 RUS73070.1 - 0.22 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain CH_2 PF06294.11 RUS73071.1 - 2e-29 101.5 0.7 3.5e-29 100.8 0.7 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RUS73071.1 - 2.2e-10 40.2 0.2 4.5e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 CAMSAP CH domain WD40 PF00400.32 RUS73072.1 - 6.6e-31 105.9 36.3 1.5e-06 28.8 0.3 9.7 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73072.1 - 1.7e-20 73.1 1.9 0.00034 20.8 0.0 7.4 3 3 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS73072.1 - 0.00031 19.5 2.6 0.67 8.5 0.0 5.1 6 0 0 6 6 6 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 RUS73072.1 - 0.011 15.8 0.0 0.41 10.7 0.0 3.5 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pilus_CpaD PF09476.10 RUS73072.1 - 0.026 14.3 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) 3Beta_HSD PF01073.19 RUS73073.1 - 1.2e-67 227.9 0.0 1.4e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS73073.1 - 1.8e-33 116.0 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RUS73073.1 - 1.4e-14 54.4 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RUS73073.1 - 5.4e-14 52.3 0.0 1.2e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 RUS73073.1 - 6.8e-13 48.4 0.0 1.9e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 RUS73073.1 - 2.6e-12 46.5 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS73073.1 - 5.1e-09 35.7 0.0 4.7e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 RUS73073.1 - 3.4e-06 26.8 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 RUS73073.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 RUS73073.1 - 0.018 15.0 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 KR domain NAD_binding_7 PF13241.6 RUS73073.1 - 0.078 13.4 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding LRR_8 PF13855.6 RUS73074.1 - 1.6e-24 85.5 19.3 1.6e-12 47.0 0.5 4.4 1 1 2 4 4 4 3 Leucine rich repeat I-set PF07679.16 RUS73074.1 - 8e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS73074.1 - 1.2e-09 38.7 0.0 2.8e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 RUS73074.1 - 2.2e-09 37.4 14.8 1.3e-05 25.5 1.2 4.4 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS73074.1 - 1.7e-06 28.0 0.0 0.0002 21.3 0.0 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 RUS73074.1 - 4.7e-05 23.5 0.0 9.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS73074.1 - 8.5e-05 22.8 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.18 RUS73074.1 - 0.015 14.9 1.6 0.05 13.3 1.6 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 RUS73074.1 - 0.035 13.6 0.6 2.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 RUS73074.1 - 1.2 9.3 6.8 48 4.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 RUS73074.1 - 4 8.4 25.3 0.08 13.5 1.2 6.7 8 0 0 8 8 7 0 Leucine Rich Repeat 7tm_1 PF00001.21 RUS73075.1 - 1.8e-17 63.6 4.3 2.3e-17 63.2 4.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS73075.1 - 0.11 11.8 17.9 0.019 14.2 13.7 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw TIR PF01582.20 RUS73076.1 - 9.7e-16 58.1 0.2 2.1e-15 57.0 0.2 1.5 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS73076.1 - 1.2e-12 48.5 0.0 2.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain SKG6 PF08693.10 RUS73076.1 - 7.2e-05 22.1 0.7 0.00015 21.1 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WD40 PF00400.32 RUS73077.1 - 1.1e-16 60.9 17.7 8e-05 23.3 0.3 8.6 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73077.1 - 1.8e-07 31.4 0.0 0.041 14.2 0.0 5.5 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CABIT PF12736.7 RUS73078.1 - 1.1e-23 83.9 0.0 2.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, DUF3480 PF11979.8 RUS73079.1 - 1.4e-151 504.4 0.0 2e-151 504.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 RUS73079.1 - 1.2e-18 66.9 11.3 2.6e-18 65.9 11.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger SARA PF11409.8 RUS73079.1 - 3.7e-12 46.2 12.5 1.2e-11 44.6 12.5 2.0 1 0 0 1 1 1 1 Smad anchor for receptor activation (SARA) FYVE_2 PF02318.16 RUS73079.1 - 0.29 11.3 9.9 0.7 10.1 9.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Muted PF14942.6 RUS73079.1 - 9.3 6.6 6.2 1.1 9.5 1.5 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein RrnaAD PF00398.20 RUS73080.1 - 1.8e-60 204.2 0.0 2.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RUS73080.1 - 4.2e-09 37.0 0.0 8.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS73080.1 - 7.5e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RUS73080.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 RUS73080.1 - 0.00021 21.2 0.0 0.00054 19.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS73080.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS73080.1 - 0.0048 16.3 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 RUS73080.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 RUS73080.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 RUS73080.1 - 0.055 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain tRNA_U5-meth_tr PF05958.11 RUS73080.1 - 0.095 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 RUS73080.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 RUS73080.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 RUS73080.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 RUS73080.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SMC_N PF02463.19 RUS73082.1 - 4.2e-70 235.6 1.7 2.1e-69 233.3 1.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RUS73082.1 - 2.8e-19 69.6 0.1 1e-18 67.7 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 RUS73082.1 - 5.9e-13 49.8 10.6 5.9e-13 49.8 10.6 6.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 RUS73082.1 - 3.3e-11 43.6 1.1 0.00026 20.9 0.6 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS73082.1 - 0.00067 19.4 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RUS73082.1 - 0.0017 18.9 0.0 0.0017 18.9 0.0 6.2 4 2 1 5 5 5 2 ABC transporter LacI PF00356.21 RUS73082.1 - 0.059 13.2 1.9 4.9 7.0 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Fungal_trans_2 PF11951.8 RUS73082.1 - 6.1 5.6 6.0 24 3.6 5.2 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain FCH PF00611.23 RUS73083.1 - 4.5e-09 36.5 0.2 8.1e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain CCDC142 PF14923.6 RUS73084.1 - 1.1e-65 222.2 13.7 3.1e-56 191.0 5.5 2.6 2 1 1 3 3 3 2 Coiled-coil protein 142 DUF5329 PF17263.2 RUS73085.1 - 0.04 14.1 0.2 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5329) MoaE PF02391.17 RUS73086.1 - 7.6e-40 135.7 0.4 9.4e-40 135.4 0.4 1.1 1 0 0 1 1 1 1 MoaE protein Pkinase_Tyr PF07714.17 RUS73087.1 - 1.2e-06 28.1 0.0 4.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Tlr3_TMD PF17968.1 RUS73087.1 - 0.48 10.6 1.5 0.94 9.7 1.5 1.4 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Avl9 PF09794.9 RUS73088.1 - 1.3e-134 448.6 0.3 1.8e-134 448.2 0.3 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 RUS73088.1 - 6.3e-11 42.4 0.2 6.2e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 RUS73088.1 - 7.1e-10 38.8 0.0 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 RUS73088.1 - 7.6e-07 29.7 0.0 7.6e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 RUS73088.1 - 4.9e-06 26.6 2.3 0.0091 16.0 0.1 2.8 4 0 0 4 4 4 2 DENN (AEX-3) domain Glutaredoxin PF00462.24 RUS73089.1 - 5.4e-15 55.4 0.0 9.7e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 RUS73089.1 - 1.4e-05 25.0 0.0 3.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 RUS73089.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 RUS73089.1 - 0.0023 18.1 0.2 0.38 10.9 0.3 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.14 RUS73089.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 RUS73089.1 - 0.056 13.2 1.7 0.31 10.8 0.2 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF1160 PF06648.11 RUS73089.1 - 0.06 13.4 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Spond_N PF06468.13 RUS73090.1 - 8.9e-45 153.2 0.0 1.3e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 RUS73090.1 - 2.7e-08 33.9 8.0 6.1e-08 32.8 8.0 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain SNAD4 PF18750.1 RUS73090.1 - 0.093 12.9 1.9 0.16 12.1 1.9 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CC2-LZ PF16516.5 RUS73091.1 - 5e-06 26.8 3.9 5e-06 26.8 3.9 5.5 2 2 2 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LUC7 PF03194.15 RUS73091.1 - 0.0075 16.0 13.0 0.0075 16.0 13.0 3.5 2 1 1 3 3 3 1 LUC7 N_terminus Glyco_tran_WecB PF03808.13 RUS73091.1 - 0.01 15.8 1.3 0.42 10.5 0.1 3.0 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Golgin_A5 PF09787.9 RUS73091.1 - 0.13 11.7 51.4 0.22 11.0 11.8 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 Filament PF00038.21 RUS73091.1 - 0.87 9.1 47.5 0.19 11.3 10.0 4.4 2 2 3 5 5 5 0 Intermediate filament protein GAS PF13851.6 RUS73091.1 - 0.96 8.8 57.0 2.6 7.4 13.6 4.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 RUS73091.1 - 8.1 6.8 45.8 2.5 8.5 7.3 3.2 1 1 2 3 3 3 0 Fez1 Keratin_assoc PF09775.9 RUS73092.1 - 7.2e-49 164.7 6.5 7.8e-49 164.6 6.5 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF4149 PF13664.6 RUS73092.1 - 0.14 12.5 8.3 0.42 11.0 8.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF3852 PF12963.7 RUS73092.1 - 0.61 10.4 4.6 0.92 9.9 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3852) Snf7 PF03357.21 RUS73093.1 - 1.2e-39 135.7 18.6 1.2e-39 135.7 18.6 1.6 2 0 0 2 2 2 1 Snf7 PSD4 PF07631.11 RUS73093.1 - 0.23 12.0 4.6 0.59 10.7 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) PhoU PF01895.19 RUS73093.1 - 0.3 11.6 12.6 1.6 9.3 1.9 3.4 3 1 0 3 3 3 0 PhoU domain Ribosomal_S21 PF01165.20 RUS73093.1 - 1.1 9.0 5.2 1.3 8.8 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S21 ACDC PF14733.6 RUS73094.1 - 0.0039 17.5 2.9 0.076 13.3 0.0 4.4 3 1 0 3 3 3 1 AP2-coincident C-terminal HEAT_2 PF13646.6 RUS73094.1 - 0.013 15.8 0.2 12 6.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeats DUF5455 PF17537.2 RUS73094.1 - 0.063 13.7 0.8 0.21 12.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5455) DUF3920 PF13058.6 RUS73094.1 - 0.095 12.9 8.1 4.2 7.6 0.9 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3920) IFRD PF05004.13 RUS73094.1 - 0.12 11.4 0.1 24 3.9 0.0 3.2 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 RUS73094.1 - 2.2 8.9 4.8 23 5.6 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat zf-H2C2_2 PF13465.6 RUS73095.1 - 1.6e-27 94.7 41.7 4.9e-07 29.9 0.3 6.5 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS73095.1 - 8.6e-16 57.4 48.6 3.7e-05 23.9 4.5 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS73095.1 - 4.1e-11 42.7 38.2 0.0027 18.4 3.4 6.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS73095.1 - 7.1e-08 32.3 35.4 0.00027 20.9 2.5 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS73095.1 - 4.3e-06 26.9 17.3 0.0022 18.2 0.3 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS73095.1 - 1.9e-05 24.9 25.7 0.0086 16.4 1.3 5.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 RUS73095.1 - 0.024 14.2 3.4 0.035 13.7 0.1 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain OSTMP1 PF09777.9 RUS73095.1 - 0.86 8.9 6.8 1.9 7.8 6.8 1.6 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Zn-ribbon_8 PF09723.10 RUS73095.1 - 1.4 9.1 14.4 4 7.6 1.3 4.4 2 1 2 4 4 4 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 RUS73095.1 - 3.6 7.4 21.6 0.91 9.3 0.7 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type RWD PF05773.22 RUS73096.1 - 5.7e-24 84.6 0.3 8.3e-24 84.1 0.3 1.2 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 RUS73096.1 - 3.8e-05 24.1 0.5 3.8e-05 24.1 0.5 2.4 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF3964 PF13107.6 RUS73096.1 - 0.036 14.4 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Ferritin PF00210.24 RUS73096.1 - 0.53 10.2 8.6 1.3 8.9 2.1 2.5 2 1 1 3 3 3 0 Ferritin-like domain TRAPP PF04051.16 RUS73097.1 - 1e-34 119.4 0.0 1.2e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CUE PF02845.16 RUS73098.1 - 3.3e-14 52.2 0.1 6.7e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 RUS73098.1 - 6.1e-13 49.0 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain HTH_8 PF02954.19 RUS73098.1 - 0.086 12.6 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Methyltransf_25 PF13649.6 RUS73101.1 - 3.7e-17 62.8 0.0 1.3e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS73101.1 - 2.1e-16 60.4 0.0 4.3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS73101.1 - 1.7e-09 37.7 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS73101.1 - 2.5e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS73101.1 - 3.9e-06 27.5 0.0 8.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RUS73101.1 - 1.6e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 RUS73101.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 RUS73101.1 - 0.0005 19.7 0.0 0.0017 18.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain LZ3wCH PF18517.1 RUS73101.1 - 0.0078 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Methyltransf_8 PF05148.15 RUS73101.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 RUS73101.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 RUS73101.1 - 0.011 15.7 0.0 0.058 13.4 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 RUS73101.1 - 0.013 15.0 0.0 0.15 11.6 0.0 2.6 3 0 0 3 3 3 0 Putative methyltransferase TPMT PF05724.11 RUS73101.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 RUS73101.1 - 0.039 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 RUS73101.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Motilin_assoc PF04643.12 RUS73106.1 - 0.033 14.1 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide YukD PF08817.10 RUS73107.1 - 0.0085 16.8 0.7 34 5.2 0.1 4.3 2 2 1 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD DUF1731 PF08338.11 RUS73108.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Epimerase PF01370.21 RUS73109.1 - 5.6e-20 71.8 0.0 6.1e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RUS73109.1 - 1.2e-09 37.7 0.0 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 RUS73109.1 - 8.3e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 RUS73109.1 - 4.1e-08 33.3 0.0 6.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RUS73109.1 - 2.8e-07 29.8 0.0 3.6e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RUS73109.1 - 4.5e-06 26.0 0.0 5.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS73109.1 - 4.1e-05 22.9 0.1 0.031 13.5 0.1 2.8 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 RUS73109.1 - 0.0018 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 RUS73109.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RNase_H PF00075.24 RUS73112.1 - 9.9e-12 45.2 0.1 9.9e-12 45.2 0.1 3.9 2 2 0 2 2 1 1 RNase H AAA_11 PF13086.6 RUS73112.1 - 0.0059 16.4 21.7 0.0065 16.3 21.7 1.2 1 0 0 1 1 1 1 AAA domain DUF913 PF06025.12 RUS73112.1 - 0.098 11.6 11.6 0.11 11.5 11.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Endostatin PF06482.11 RUS73112.1 - 0.22 10.9 13.1 0.26 10.7 13.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3807 PF12720.7 RUS73112.1 - 0.26 11.5 40.2 0.52 10.6 40.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4776 PF16003.5 RUS73112.1 - 0.27 10.2 43.5 0.36 9.8 43.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Membralin PF09746.9 RUS73112.1 - 0.28 10.2 13.9 0.35 9.9 13.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein SOBP PF15279.6 RUS73112.1 - 0.39 11.3 16.3 0.47 11.0 16.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 RUS73112.1 - 0.4 8.8 15.2 0.42 8.7 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 RUS73112.1 - 1.3 8.8 41.1 1.9 8.3 41.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 RUS73112.1 - 1.7 5.6 14.3 1.8 5.6 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF262 PF03235.14 RUS73112.1 - 1.8 8.7 14.7 2.2 8.4 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DAG_kinase_N PF14513.6 RUS73112.1 - 3.6 7.8 27.7 18 5.5 27.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus U79_P34 PF03064.16 RUS73112.1 - 5.1 6.4 35.5 6.4 6.1 35.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2126 PF09899.9 RUS73112.1 - 5.2 5.0 13.6 7.6 4.5 13.6 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 RUS73112.1 - 7.8 5.4 33.2 9.7 5.1 33.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 RUS73112.1 - 8.3 4.7 10.5 8.5 4.7 10.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Exo_endo_phos_2 PF14529.6 RUS73113.1 - 2.1e-10 40.5 0.2 2.1e-10 40.5 0.2 2.6 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase DUF4407 PF14362.6 RUS73113.1 - 2.8 7.2 5.7 5 6.4 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1798 PF08807.10 RUS73113.1 - 6.7 6.9 8.5 1.9 8.6 3.2 2.3 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Rot1 PF10681.9 RUS73114.1 - 0.15 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal CUB PF00431.20 RUS73115.1 - 1.6e-16 60.6 0.4 5.4e-15 55.7 0.0 2.0 2 0 0 2 2 2 2 CUB domain DHC_N2 PF08393.13 RUS73116.1 - 0.15 11.1 0.3 18 4.3 0.0 2.4 3 0 0 3 3 3 0 Dynein heavy chain, N-terminal region 2 RT_RNaseH_2 PF17919.1 RUS73117.1 - 6.1e-34 116.0 0.0 1.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS73117.1 - 2.2e-33 114.7 0.0 3.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS73117.1 - 3.2e-22 79.1 0.1 5.5e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS73117.1 - 9.6e-13 48.0 0.1 1.9e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain C2 PF00168.30 RUS73118.1 - 2.1e-38 130.7 0.3 1.5e-17 63.7 0.0 4.3 3 1 0 3 3 3 3 C2 domain Membr_traf_MHD PF10540.9 RUS73118.1 - 4.3e-10 40.0 3.7 0.00054 20.1 0.8 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain Profilin PF00235.19 RUS73120.1 - 2.1e-24 86.2 0.0 3.2e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Profilin RGM_N PF06535.12 RUS73121.1 - 0.025 14.8 16.5 0.53 10.5 0.5 2.5 2 1 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Galactosyl_T PF01762.21 RUS73122.1 - 6.3e-26 91.4 0.2 1.8e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase Laminin_EGF PF00053.24 RUS73122.1 - 0.0097 16.0 3.2 0.025 14.7 3.2 1.6 1 0 0 1 1 1 1 Laminin EGF domain EGF_2 PF07974.13 RUS73122.1 - 0.11 12.9 2.7 0.24 11.8 2.7 1.6 1 0 0 1 1 1 0 EGF-like domain Presenilin PF01080.17 RUS73122.1 - 5.3 5.7 9.8 8 5.1 9.8 1.2 1 0 0 1 1 1 0 Presenilin Galactosyl_T PF01762.21 RUS73123.1 - 1.4e-36 126.2 0.0 2.5e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase CTP_transf_1 PF01148.20 RUS73127.1 - 6.7e-81 271.9 24.3 8.2e-81 271.7 24.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TTC5_OB PF16669.5 RUS73127.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain MAPKK1_Int PF08923.10 RUS73128.1 - 1.5e-37 128.1 0.9 1.6e-37 127.9 0.9 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF2322 PF10084.9 RUS73128.1 - 0.076 13.1 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Sec7 PF01369.20 RUS73129.1 - 8e-62 208.2 1.0 1.4e-61 207.4 1.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RUS73129.1 - 7.4e-24 84.4 3.9 7.4e-24 84.4 3.9 3.4 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal UME PF08064.13 RUS73129.1 - 0.038 13.9 0.7 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 UME (NUC010) domain DUF1045 PF06299.12 RUS73129.1 - 0.055 13.4 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Plasmodium_HRP PF05403.11 RUS73130.1 - 0.0001 22.2 30.2 0.00014 21.8 30.2 1.2 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) FAM47 PF14642.6 RUS73130.1 - 2 7.9 33.5 3.7 7.0 11.3 3.1 1 1 2 3 3 3 0 FAM47 family BDM PF10684.9 RUS73131.1 - 0.074 13.4 5.6 1.1e+02 3.3 0.0 5.3 1 1 4 5 5 5 0 Putative biofilm-dependent modulation protein DBB PF14545.6 RUS73131.1 - 0.77 9.7 6.0 22 5.0 0.8 3.6 1 1 2 3 3 3 0 Dof, BCAP, and BANK (DBB) motif, 7tm_1 PF00001.21 RUS73132.1 - 5.1e-13 48.9 0.1 1.2e-12 47.7 0.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS73132.1 - 1.1e-05 24.9 3.9 0.02 14.3 3.9 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 RUS73132.1 - 1.8 8.1 15.6 0.28 10.8 10.8 2.0 2 1 0 2 2 2 0 Srg family chemoreceptor polyprenyl_synt PF00348.17 RUS73133.1 - 4.7e-66 222.5 0.0 5.6e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Zip PF02535.22 RUS73134.1 - 3.5e-21 75.8 5.9 1e-20 74.3 5.9 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol_B_exo1 PF03104.19 RUS73135.1 - 8.9e-49 166.4 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF826 PF05696.11 RUS73135.1 - 0.21 11.7 0.1 0.47 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF826) BPL_LplA_LipB PF03099.19 RUS73136.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 RUS73136.1 - 0.0063 15.6 0.1 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal Guanylate_cyc PF00211.20 RUS73138.1 - 6.4e-52 175.8 0.0 1.1e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS73138.1 - 3.5e-36 124.8 1.3 3e-35 121.8 1.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS73138.1 - 3.6e-36 124.9 0.1 1e-35 123.4 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 RUS73138.1 - 1.1e-06 28.3 1.0 2.1e-06 27.4 1.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated HSP90 PF00183.18 RUS73139.1 - 1.3e-34 120.0 7.8 2.1e-32 112.7 4.0 2.0 1 1 1 2 2 2 2 Hsp90 protein PRP3 PF08572.10 RUS73139.1 - 0.019 14.7 0.2 0.024 14.4 0.2 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) HATPase_c PF02518.26 RUS73139.1 - 0.042 14.3 0.0 0.094 13.2 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lectin_C PF00059.21 RUS73141.1 - 8.4e-12 45.8 0.1 1.4e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain Lipin_N PF04571.14 RUS73141.1 - 0.017 15.1 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 lipin, N-terminal conserved region REJ PF02010.15 RUS73142.1 - 0.00093 18.1 0.1 0.00097 18.0 0.1 1.0 1 0 0 1 1 1 1 REJ domain CDC45 PF02724.14 RUS73143.1 - 1.6 6.9 6.8 2.2 6.5 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 RUS73144.1 - 9.5e-07 28.6 0.6 2.4e-06 27.3 0.5 1.7 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS73144.1 - 1.2e-06 28.3 1.0 1.2e-06 28.3 1.0 1.6 2 0 0 2 2 2 1 F-box-like DUF4508 PF14969.6 RUS73144.1 - 4.2e-06 26.9 4.2 0.00045 20.4 0.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4508) Peptidase_S8 PF00082.22 RUS73146.1 - 4.9e-45 154.1 0.5 4.9e-45 154.1 0.5 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 RUS73146.1 - 5.4e-18 64.8 0.1 1.9e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 RUS73146.1 - 1.8e-09 38.2 1.5 7.6e-09 36.2 0.1 2.7 2 0 0 2 2 2 1 Peptidase S8 pro-domain DUF1676 PF07898.13 RUS73146.1 - 7 6.7 5.1 2.3 8.2 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Bcl-2 PF00452.19 RUS73147.1 - 7.1e-20 71.5 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DHHC PF01529.20 RUS73149.1 - 7.4e-29 100.5 16.2 7.4e-29 100.5 16.2 2.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Coprogen_oxidas PF01218.18 RUS73150.1 - 1.5e-139 463.8 0.2 1.7e-139 463.6 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase UDPGT PF00201.18 RUS73151.1 - 4.4e-73 246.8 0.2 5.8e-73 246.4 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RUS73151.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_7N PF13733.6 RUS73152.1 - 1.6e-46 157.2 0.1 2.3e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS73152.1 - 2e-24 85.0 0.2 3.4e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase WD40 PF00400.32 RUS73153.1 - 5.7e-14 52.3 4.2 0.044 14.7 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73153.1 - 3.4e-07 30.4 0.0 0.028 14.7 0.0 4.6 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.23 RUS73154.1 - 6.4e-06 25.9 0.0 7.1e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase_Tyr PF07714.17 RUS73155.1 - 3.2e-74 249.5 0.0 4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS73155.1 - 4.8e-27 95.0 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RUS73155.1 - 6.6e-06 25.6 0.2 1.5e-05 24.5 0.2 1.5 1 1 0 1 1 1 1 Kinase-like ABC_tran PF00005.27 RUS73156.1 - 5.2e-53 179.2 0.2 3.4e-27 95.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RUS73156.1 - 3.4e-19 69.6 15.7 2.5e-10 40.5 10.3 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RUS73156.1 - 1.2e-07 31.4 5.9 0.0035 16.8 0.0 3.6 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS73156.1 - 0.00037 20.6 0.2 0.8 9.8 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS73156.1 - 0.0035 17.8 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RUS73156.1 - 0.012 16.2 0.3 7.6 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RUS73156.1 - 0.023 14.4 8.5 0.38 10.5 0.2 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS73156.1 - 0.028 14.3 2.9 1 9.2 0.3 2.5 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 RUS73156.1 - 0.045 13.5 1.7 9 6.0 0.1 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 RUS73156.1 - 0.072 13.4 1.9 16 5.7 0.2 3.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 RUS73156.1 - 0.14 11.9 1.3 0.22 11.3 0.1 1.9 2 0 0 2 2 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 RUS73156.1 - 0.35 11.3 9.9 0.16 12.5 0.6 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 RUS73156.1 - 0.6 9.2 6.7 0.31 10.2 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 RUS73156.1 - 0.86 9.8 2.3 9.3 6.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 RUS73156.1 - 1.2 8.8 3.2 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 RUS73156.1 - 2.4 8.2 7.2 0.42 10.7 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DUF2207 PF09972.9 RUS73156.1 - 5.7 5.6 6.8 1.7 7.3 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FAM176 PF14851.6 RUS73156.1 - 8.5 6.0 11.0 5 6.8 3.3 2.5 2 0 0 2 2 2 0 FAM176 family DUF2457 PF10446.9 RUS73156.1 - 8.6 5.4 33.3 5.4 6.0 26.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF4793 PF16041.5 RUS73159.1 - 0.014 15.6 0.0 14 5.9 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4793) DUF3827 PF12877.7 RUS73159.1 - 0.074 11.4 0.1 0.074 11.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) 7tm_1 PF00001.21 RUS73160.1 - 1.9e-17 63.5 13.8 1.9e-17 63.5 13.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73160.1 - 0.00094 18.9 9.5 0.00094 18.9 9.5 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS73160.1 - 0.0029 17.0 10.4 0.0046 16.4 10.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS73160.1 - 0.0056 16.0 15.1 0.033 13.5 1.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw CENP-B_dimeris PF09026.10 RUS73160.1 - 0.015 15.7 2.2 3.3 8.2 0.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRIQK PF15168.6 RUS73160.1 - 0.36 10.7 1.6 5.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Serpentine_r_xa PF03383.15 RUS73160.1 - 0.68 9.9 12.2 0.19 11.7 1.2 3.0 2 1 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa DUF2070 PF09843.9 RUS73160.1 - 7.1 4.8 15.3 2.7 6.2 12.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Lectin_C PF00059.21 RUS73161.1 - 1.4e-13 51.5 0.1 2.9e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS73161.1 - 0.0069 16.3 2.3 0.014 15.3 1.8 1.9 1 1 1 2 2 2 1 PAN domain Surp PF01805.20 RUS73162.1 - 1.7e-43 146.4 6.1 4.7e-23 80.9 0.4 2.4 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 RUS73162.1 - 5.5e-18 65.6 4.0 8.9e-18 64.9 4.0 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein HAD_2 PF13419.6 RUS73163.1 - 1.3e-24 87.2 0.0 1.6e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS73163.1 - 5.1e-15 56.3 0.2 8.1e-14 52.4 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS73163.1 - 0.0011 19.4 0.0 0.0015 19.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS73163.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RUS73163.1 - 0.022 14.9 0.1 1.5 9.0 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DcrB PF08786.11 RUS73163.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 DcrB CBM_14 PF01607.24 RUS73164.1 - 2.4e-18 66.0 13.3 9.8e-09 35.2 2.2 3.4 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Aconitase_B_N PF11791.8 RUS73164.1 - 0.28 11.2 0.0 30 4.7 0.0 2.1 2 0 0 2 2 2 0 Aconitate B N-terminal domain SR-25 PF10500.9 RUS73164.1 - 0.48 10.0 19.6 0.72 9.4 19.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bcl-2 PF00452.19 RUS73166.1 - 3.4e-12 46.9 0.1 1.5e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family WXG100 PF06013.12 RUS73166.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Peptidase_C1 PF00112.23 RUS73167.1 - 6e-34 118.0 3.3 7.5e-34 117.7 3.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PKD PF00801.20 RUS73168.1 - 0.007 16.2 1.3 0.007 16.2 1.3 2.2 2 0 0 2 2 2 1 PKD domain PPC PF04151.15 RUS73168.1 - 0.063 14.4 3.6 3.5 8.8 1.6 2.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain REJ PF02010.15 RUS73169.1 - 1.3e-33 116.5 8.6 2.1e-33 115.8 8.6 1.3 1 0 0 1 1 1 1 REJ domain PKD PF00801.20 RUS73169.1 - 0.053 13.4 0.2 0.28 11.1 0.2 2.3 1 0 0 1 1 1 0 PKD domain CUB PF00431.20 RUS73172.1 - 3.4e-08 33.8 0.0 3.3e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 CUB domain Sushi PF00084.20 RUS73172.1 - 5.5e-08 33.3 0.2 1e-07 32.4 0.2 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Peptidase_S58 PF03576.14 RUS73172.1 - 0.028 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S58 Sushi PF00084.20 RUS73173.1 - 7.3e-25 87.3 37.4 3.5e-08 33.9 0.1 7.6 8 0 0 8 8 8 5 Sushi repeat (SCR repeat) EGF_CA PF07645.15 RUS73173.1 - 1.4e-14 54.0 14.8 1.5e-07 31.5 1.8 4.6 4 0 0 4 4 4 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS73173.1 - 2.3e-07 31.0 30.1 0.00048 20.4 6.9 5.7 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS73173.1 - 5.1e-07 29.5 40.3 2.9e-05 23.9 3.0 8.6 8 1 0 8 8 8 3 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS73173.1 - 0.027 14.6 16.0 0.21 11.8 3.1 4.1 3 0 0 3 3 3 0 EGF domain HYR PF02494.16 RUS73175.1 - 2.7e-15 56.5 1.4 6.2e-15 55.3 1.4 1.7 1 0 0 1 1 1 1 HYR domain EGF PF00008.27 RUS73175.1 - 1.4e-12 47.6 36.0 9.9e-07 29.0 6.7 5.9 5 0 0 5 5 5 5 EGF-like domain Laminin_G_3 PF13385.6 RUS73175.1 - 1.3e-09 38.4 0.0 3.6e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 RUS73175.1 - 0.011 16.1 4.0 0.011 16.1 4.0 5.0 4 0 0 4 4 4 0 EGF-like domain Laminin_G_2 PF02210.24 RUS73175.1 - 0.074 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain hEGF PF12661.7 RUS73175.1 - 8 7.3 31.2 0.078 13.6 2.5 5.5 5 0 0 5 5 5 0 Human growth factor-like EGF Ephrin_rec_like PF07699.13 RUS73176.1 - 4.1e-43 144.9 56.5 2.6e-14 52.7 7.7 5.5 4 1 1 5 5 5 4 Putative ephrin-receptor like SR-25 PF10500.9 RUS73176.1 - 0.0023 17.6 5.8 0.0042 16.7 5.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EGF_3 PF12947.7 RUS73176.1 - 0.0025 17.9 5.2 0.021 15.0 5.2 2.8 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 RUS73176.1 - 0.006 16.8 8.3 0.006 16.8 8.3 6.2 6 3 1 7 7 7 1 Calcium-binding EGF domain TAF1D PF15333.6 RUS73176.1 - 0.47 10.1 4.8 1.8 8.2 5.0 1.7 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF2457 PF10446.9 RUS73178.1 - 1.2e-06 28.0 31.1 1.7e-06 27.4 31.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Caldesmon PF02029.15 RUS73178.1 - 1.2e-05 24.3 28.7 1.3e-05 24.2 28.7 1.1 1 0 0 1 1 1 1 Caldesmon TFIIF_alpha PF05793.12 RUS73178.1 - 3.5e-05 22.6 30.6 4.5e-05 22.2 30.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 RUS73178.1 - 0.00011 20.7 25.7 0.00012 20.5 25.7 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 RUS73178.1 - 0.00014 21.4 27.6 0.00016 21.2 27.6 1.1 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 RUS73178.1 - 0.00068 19.8 31.7 0.00078 19.6 31.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Presenilin PF01080.17 RUS73178.1 - 0.0031 16.3 16.0 0.0032 16.3 16.0 1.1 1 0 0 1 1 1 1 Presenilin CCSAP PF15748.5 RUS73178.1 - 0.018 15.2 19.5 0.027 14.6 19.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 RUS73178.1 - 0.045 13.3 19.7 0.051 13.1 19.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2828 PF11443.8 RUS73178.1 - 0.054 11.6 9.4 0.052 11.6 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MDM1 PF15501.6 RUS73178.1 - 0.086 12.0 26.2 0.12 11.5 26.2 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 Nop14 PF04147.12 RUS73178.1 - 0.16 10.1 50.3 0.21 9.8 50.3 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 RUS73178.1 - 0.2 10.7 18.3 0.26 10.3 18.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 RUS73178.1 - 0.21 11.0 47.3 0.32 10.4 47.3 1.2 1 0 0 1 1 1 0 SDA1 DUF3807 PF12720.7 RUS73178.1 - 0.39 11.0 26.1 0.61 10.3 26.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Zip PF02535.22 RUS73178.1 - 0.4 9.8 11.9 0.44 9.7 11.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 RUS73178.1 - 0.45 8.9 49.5 0.55 8.6 49.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Peptidase_S64 PF08192.11 RUS73178.1 - 0.65 8.4 13.4 0.71 8.3 13.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tim54 PF11711.8 RUS73178.1 - 0.68 8.7 26.4 1.1 8.0 26.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LTV PF04180.14 RUS73178.1 - 1.8 8.2 26.4 2.1 8.0 26.4 1.1 1 0 0 1 1 1 0 Low temperature viability protein Mem_trans PF03547.18 RUS73178.1 - 2 6.7 6.0 2.2 6.6 6.0 1.3 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 RUS73178.1 - 2.1 5.4 11.6 2.3 5.2 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SpoIIIAH PF12685.7 RUS73178.1 - 3.2 7.5 25.6 5 6.9 25.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PPL5 PF18168.1 RUS73178.1 - 4.3 6.6 19.0 5.9 6.1 19.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF5427 PF10310.9 RUS73178.1 - 4.8 6.0 25.1 6.4 5.6 25.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Gti1_Pac2 PF09729.9 RUS73178.1 - 5.2 7.1 14.5 8.8 6.4 14.5 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4045 PF13254.6 RUS73178.1 - 7.4 6.1 22.7 11 5.6 22.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Peptidase_M13_N PF05649.13 RUS73179.1 - 2.4e-67 228.3 0.0 3.6e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS73179.1 - 6.3e-58 195.8 0.0 1.3e-57 194.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 LRR_8 PF13855.6 RUS73180.1 - 1.9e-15 56.4 0.0 9e-05 22.2 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 RUS73180.1 - 4.9e-08 33.0 0.0 9.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DAN PF03045.15 RUS73181.1 - 5.6e-06 26.4 10.5 1.1e-05 25.4 10.5 1.5 1 0 0 1 1 1 1 DAN domain Tubulin PF00091.25 RUS73182.1 - 1.9e-60 204.5 0.0 2.8e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS73182.1 - 9.4e-36 122.8 0.0 1.8e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS73182.1 - 0.00013 22.2 0.0 0.00045 20.5 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS73182.1 - 0.0083 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RUS73182.1 - 0.032 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like AIP3 PF03915.13 RUS73183.1 - 3.3e-34 118.7 11.4 4.2e-21 75.5 9.5 2.2 2 0 0 2 2 2 2 Actin interacting protein 3 HeLo PF14479.6 RUS73183.1 - 5.8 6.7 8.1 0.58 9.9 2.1 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation Thiolase_C PF02803.18 RUS73186.1 - 1.4e-46 157.1 0.3 2.8e-46 156.2 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 RUS73186.1 - 2e-39 135.5 0.0 4.4e-39 134.4 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain HLH PF00010.26 RUS73187.1 - 0.00016 21.5 0.3 0.00035 20.5 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Actin PF00022.19 RUS73188.1 - 7e-135 449.8 0.0 7.9e-135 449.6 0.0 1.0 1 0 0 1 1 1 1 Actin Pkinase PF00069.25 RUS73189.1 - 1.1e-48 165.9 0.0 2.1e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73189.1 - 2.2e-21 76.3 0.0 3.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 RUS73189.1 - 0.0043 16.7 0.2 0.57 9.8 0.1 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Troponin PF00992.20 RUS73190.1 - 7.9e-35 120.1 15.7 7.9e-35 120.1 15.7 3.6 3 2 1 4 4 4 1 Troponin H_lectin PF09458.10 RUS73192.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 H-type lectin domain PsbP PF01789.16 RUS73192.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 PsbP Antistasin PF02822.14 RUS73193.1 - 0.00038 21.0 8.6 0.00038 21.0 8.6 3.9 5 2 0 5 5 5 1 Antistasin family WAP PF00095.21 RUS73193.1 - 0.00086 19.6 11.0 0.00086 19.6 11.0 3.3 2 2 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' WAP PF00095.21 RUS73194.1 - 5e-08 33.2 4.7 5e-08 33.2 4.7 4.3 3 2 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF3504 PF12012.8 RUS73195.1 - 2.3e-10 40.6 0.1 4.9e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Ank_2 PF12796.7 RUS73196.1 - 8.1e-09 36.0 1.5 0.41 11.3 0.0 5.5 5 2 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS73196.1 - 0.0005 20.6 3.2 4 8.2 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS73196.1 - 0.00052 20.3 16.3 2.9 8.5 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 RUS73196.1 - 0.0024 18.2 12.7 59 4.7 0.0 8.3 8 1 1 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 RUS73196.1 - 0.005 17.1 1.8 15 6.0 0.0 4.9 6 0 0 6 6 6 1 Ankyrin repeats (many copies) 7tm_1 PF00001.21 RUS73197.1 - 2.8e-07 30.2 3.2 3.2e-07 30.0 3.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Utp14 PF04615.13 RUS73199.1 - 6.4e-103 345.8 71.7 3.3e-61 207.8 37.3 2.2 1 1 0 2 2 2 2 Utp14 protein DNA_ligase_A_C PF04679.15 RUS73199.1 - 0.0066 17.0 4.3 0.51 11.0 0.2 3.2 2 0 0 2 2 2 2 ATP dependent DNA ligase C terminal region T4bSS_IcmS PF12608.8 RUS73199.1 - 1.6 9.1 5.9 1.1 9.6 1.3 3.0 2 2 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment TTL PF03133.15 RUS73200.1 - 5.7e-72 242.3 0.2 2.9e-71 240.0 0.2 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS73200.1 - 2.4e-06 27.0 0.1 0.00022 20.6 0.1 3.0 1 1 1 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS73200.1 - 0.026 13.8 0.0 0.97 8.6 0.0 2.5 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RUS73200.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Sec63 PF02889.16 RUS73201.1 - 3e-16 59.4 2.3 1.2e-07 31.2 0.4 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 RUS73201.1 - 2e-15 56.7 0.1 4.6e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DERM PF14704.6 RUS73202.1 - 6.4e-23 81.9 1.8 2.7e-22 79.9 1.7 1.7 1 1 0 1 1 1 1 Dermatopontin CBM_14 PF01607.24 RUS73205.1 - 1.4e-14 54.0 16.8 2.5e-10 40.4 2.8 4.0 4 1 0 4 4 4 2 Chitin binding Peritrophin-A domain EGF PF00008.27 RUS73205.1 - 1.9e-09 37.7 39.5 2e-05 24.8 6.5 5.3 6 0 0 6 6 6 3 EGF-like domain EGF_alliinase PF04863.13 RUS73205.1 - 0.002 18.5 31.5 0.062 13.7 5.6 4.5 3 2 1 4 4 4 3 Alliinase EGF-like domain FXa_inhibition PF14670.6 RUS73205.1 - 0.0039 17.5 39.5 0.28 11.5 6.5 4.4 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 RUS73205.1 - 0.019 15.3 11.2 0.019 15.3 11.2 4.6 4 0 0 4 4 4 0 EGF-like domain cEGF PF12662.7 RUS73205.1 - 0.064 13.2 20.8 1.1 9.3 1.1 4.5 4 0 0 4 4 4 0 Complement Clr-like EGF-like Ependymin PF00811.18 RUS73206.1 - 2.8e-32 111.6 0.0 3.5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 RUS73207.1 - 1.9e-31 108.9 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Ependymin GTP_EFTU PF00009.27 RUS73209.1 - 1.2e-61 207.7 0.0 2.1e-61 206.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RUS73209.1 - 2.7e-29 101.1 0.0 6.4e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RUS73209.1 - 1.9e-22 79.1 0.2 4e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RUS73209.1 - 8.3e-11 42.1 0.0 2.1e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RUS73209.1 - 3.6e-10 39.8 0.0 8.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 RUS73209.1 - 1.1e-09 38.2 0.0 2.8e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 RUS73209.1 - 0.0011 19.0 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RUS73209.1 - 0.045 13.1 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family LSM PF01423.22 RUS73210.1 - 2.6e-18 65.4 0.4 3.5e-18 65.0 0.4 1.2 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.20 RUS73211.1 - 1.8e-30 105.6 0.0 9.3e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Acyltransf_C PF16076.5 RUS73212.1 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 RUS73212.1 - 3.1e-08 33.3 0.0 7.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase ApeC PF16977.5 RUS73213.1 - 1.1e-36 126.7 0.1 2e-36 125.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of apextrin DUF16 PF01519.16 RUS73213.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1627 PF07789.12 RUS73213.1 - 0.1 12.2 1.7 0.16 11.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Med3 PF11593.8 RUS73213.1 - 0.17 11.0 5.5 0.24 10.6 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.17 RUS73213.1 - 0.25 11.3 24.1 0.45 10.5 24.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 RUS73213.1 - 7.2 4.5 5.8 12 3.7 5.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 RUS73213.1 - 7.5 4.6 8.1 9.9 4.1 8.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NIF PF03031.18 RUS73215.1 - 4.6e-51 172.7 0.3 1.3e-50 171.2 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PIP5K PF01504.18 RUS73218.1 - 1.3e-86 290.3 0.9 1.8e-86 289.8 0.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TraH_2 PF06871.11 RUS73218.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 TraH_2 Spt20 PF12090.8 RUS73219.1 - 0.034 13.7 15.0 0.058 13.0 15.0 1.3 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.9 RUS73219.1 - 0.74 8.3 7.2 0.89 8.0 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Inj_translocase PF16928.5 RUS73219.1 - 2.3 7.6 11.6 3.5 7.0 11.6 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome DUF4834 PF16118.5 RUS73219.1 - 7.8 7.5 8.2 20 6.2 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CAP PF00188.26 RUS73221.1 - 2.1e-20 73.8 8.4 2.6e-20 73.5 8.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NAP PF00956.18 RUS73222.1 - 1.4e-23 83.4 0.1 3.1e-23 82.3 0.1 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) His_Phos_2 PF00328.22 RUS73222.1 - 2e-18 66.9 0.0 2.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LIN52 PF10044.9 RUS73223.1 - 2.8e-38 130.5 0.1 3.9e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Retinal tissue protein DUF3011 PF11218.8 RUS73224.1 - 3.5e-24 85.9 7.0 3.1e-17 63.2 1.3 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3011) EGF PF00008.27 RUS73225.1 - 1.2e-21 76.6 110.9 8.4e-08 32.4 10.6 7.7 7 2 0 7 7 7 5 EGF-like domain hEGF PF12661.7 RUS73225.1 - 2.4e-11 43.8 87.7 0.0019 18.7 9.1 7.6 7 1 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 RUS73225.1 - 3.3e-10 40.2 119.8 9.2e-05 22.7 12.8 8.1 6 2 2 8 8 8 5 EGF-like domain EF-hand_6 PF13405.6 RUS73227.1 - 6.4e-07 28.8 0.1 0.016 15.1 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS73227.1 - 8e-07 29.4 0.0 0.00064 20.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS73227.1 - 8.3e-06 25.6 0.1 0.0081 16.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS73227.1 - 1.3e-05 24.4 0.0 0.036 13.6 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 RUS73227.1 - 0.02 15.2 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain FliMN_C PF01052.20 RUS73230.1 - 0.002 18.1 7.2 34 4.5 0.0 7.2 4 2 5 9 9 9 2 Type III flagellar switch regulator (C-ring) FliN C-term MOSC PF03473.17 RUS73230.1 - 0.0021 18.1 0.0 1 9.4 0.0 4.4 3 2 1 4 4 4 1 MOSC domain UvrD_C_2 PF13538.6 RUS73231.1 - 6e-09 35.6 0.0 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 RUS73231.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1720 PF08226.11 RUS73235.1 - 0.016 15.6 2.7 1.3 9.5 2.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) DUF4173 PF13777.6 RUS73235.1 - 3 7.2 19.2 10 5.5 1.1 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4173) TAF1_subA PF14929.6 RUS73236.1 - 9.2e-40 137.2 4.3 1.3e-39 136.7 4.3 1.1 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A DUF410 PF04190.13 RUS73236.1 - 0.0058 16.5 0.2 0.033 14.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF410) TPR_19 PF14559.6 RUS73236.1 - 0.018 15.5 0.0 2.2 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73236.1 - 0.033 15.0 0.0 9.2 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.12 RUS73236.1 - 0.073 12.6 0.1 1 8.8 0.0 2.4 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor CSN8_PSD8_EIF3K PF10075.9 RUS73237.1 - 2e-29 102.4 0.0 2.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family MEA1 PF06910.11 RUS73238.1 - 3e-15 57.0 4.3 3.3e-14 53.6 4.3 2.1 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) B56 PF01603.20 RUS73239.1 - 1.1e-197 657.0 5.4 1.4e-197 656.7 5.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3760 PF12586.8 RUS73239.1 - 0.16 12.2 0.5 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) PROL5-SMR PF15621.6 RUS73239.1 - 0.19 12.3 2.5 40 4.8 0.1 3.3 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family Metallophos PF00149.28 RUS73240.1 - 5.5e-41 141.3 0.0 6.9e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS73240.1 - 1.5e-21 76.5 0.4 3.4e-21 75.4 0.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Kp4 PF09044.10 RUS73241.1 - 0.071 13.2 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 Kp4 Methyltransf_16 PF10294.9 RUS73242.1 - 2.8e-15 56.5 0.0 4.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 RUS73242.1 - 0.054 14.2 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RUS73242.1 - 0.093 13.5 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TAF8_C PF10406.9 RUS73243.1 - 1.1e-18 67.5 0.6 1.7e-18 66.9 0.6 1.3 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 RUS73243.1 - 8.3e-18 64.2 0.1 2.3e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 RUS73243.1 - 0.0028 17.7 0.1 0.0077 16.3 0.1 1.6 1 1 1 2 2 2 1 Transcription initiation factor IID, 31kD subunit Homeodomain PF00046.29 RUS73245.1 - 2.2e-22 78.7 2.5 3.9e-22 77.8 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS73245.1 - 0.0014 18.5 0.1 0.0039 17.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Condensin2nSMC PF12422.8 RUS73246.1 - 0.013 15.7 0.9 0.052 13.7 0.7 2.1 1 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit DUF445 PF04286.12 RUS73246.1 - 0.066 13.0 7.9 0.18 11.6 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Dimer_Tnp_hAT PF05699.14 RUS73247.1 - 2.3e-12 46.5 0.0 7.8e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 RUS73247.1 - 3.7e-09 36.5 1.7 8.1e-09 35.4 1.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4602 PF15375.6 RUS73247.1 - 0.13 12.5 0.8 0.26 11.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) zf-C2H2_7 PF15269.6 RUS73247.1 - 1.1 9.4 4.2 0.83 9.8 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger Pentapeptide_4 PF13599.6 RUS73249.1 - 9.6e-07 28.9 0.0 0.0022 18.2 0.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) CTD PF12815.7 RUS73249.1 - 1.1 9.9 4.3 6.7 7.4 4.3 2.6 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Pentapeptide PF00805.22 RUS73250.1 - 0.029 14.0 0.0 2.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) DUF2892 PF11127.8 RUS73250.1 - 1.3 9.1 14.6 1.4 9.0 2.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2892) zf-C2H2 PF00096.26 RUS73251.1 - 1.3e-46 154.6 92.2 1.1e-07 31.9 2.8 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73251.1 - 2.8e-31 106.5 105.4 3.2e-07 30.5 2.3 10.7 11 0 0 11 11 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS73251.1 - 3.6e-29 98.9 85.3 0.00078 20.1 1.8 9.7 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS73251.1 - 5.5e-09 35.6 55.8 0.00051 19.7 0.1 8.6 9 0 0 9 9 9 6 zinc-finger C2H2-type zf_UBZ PF18439.1 RUS73251.1 - 0.00049 19.6 51.8 0.21 11.2 0.1 9.2 9 0 0 9 9 9 6 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 RUS73251.1 - 0.0053 17.0 5.4 0.0053 17.0 5.4 9.6 10 1 0 10 10 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RUS73251.1 - 0.0076 16.9 39.6 0.75 10.5 0.9 7.2 3 2 3 6 6 6 2 Zinc finger C2H2-type, 3 repeats C1_1 PF00130.22 RUS73251.1 - 0.024 14.5 59.7 0.15 11.9 1.3 7.9 1 1 7 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 RUS73251.1 - 0.024 14.4 2.2 0.024 14.4 2.2 12.3 14 2 0 14 14 13 0 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 RUS73251.1 - 0.037 13.9 1.7 0.037 13.9 1.7 6.5 5 1 0 5 5 4 0 SprT-like zinc ribbon domain BolA PF01722.18 RUS73251.1 - 1.4 9.2 11.2 12 6.3 0.8 4.2 4 1 1 5 5 5 0 BolA-like protein Zn-ribbon_8 PF09723.10 RUS73251.1 - 7.3 6.8 63.5 0.24 11.5 5.5 7.9 4 2 4 8 8 7 0 Zinc ribbon domain GAGA PF09237.11 RUS73251.1 - 9.1 6.2 8.6 25 4.8 0.2 4.0 3 1 1 4 4 4 0 GAGA factor PAP2_C PF14360.6 RUS73252.1 - 8.4e-25 87.1 11.8 8.4e-25 87.1 11.8 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 RUS73252.1 - 3.2e-10 40.3 0.2 5.6e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 RUS73252.1 - 9.4e-05 22.2 8.3 9.4e-05 22.2 8.3 2.5 2 1 1 3 3 3 1 PAP2 superfamily SAM_2 PF07647.17 RUS73252.1 - 0.00047 20.2 0.1 0.00091 19.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RUS73252.1 - 0.0094 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Porin_3 PF01459.22 RUS73253.1 - 1.5e-60 205.0 5.5 1.9e-60 204.6 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic porin TGF_beta PF00019.20 RUS73254.1 - 2.7e-28 99.0 1.3 9e-28 97.3 1.3 2.0 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS73254.1 - 5.3e-08 32.9 0.3 5.3e-08 32.9 0.3 2.2 1 1 1 2 2 2 1 TGF-beta propeptide DAN PF03045.15 RUS73254.1 - 0.011 15.8 1.2 0.011 15.8 1.2 2.1 2 0 0 2 2 2 0 DAN domain Adipokin_hormo PF06377.11 RUS73255.1 - 0.0039 17.5 0.1 0.0083 16.5 0.1 1.6 1 0 0 1 1 1 1 Adipokinetic hormone ParA PF10609.9 RUS73256.1 - 2.8e-30 105.6 0.0 3.1e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Pkinase PF00069.25 RUS73257.1 - 1.6e-30 106.4 0.8 2.9e-30 105.5 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73257.1 - 2.5e-19 69.6 0.1 1.9e-18 66.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS73257.1 - 0.053 12.9 0.1 0.089 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RUS73259.1 - 3.5e-14 52.8 0.1 1.8e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73259.1 - 5.3e-07 29.2 0.0 9.6e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase STAT_int PF02865.17 RUS73260.1 - 0.092 13.2 0.1 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 STAT protein, protein interaction domain PAN_1 PF00024.26 RUS73262.1 - 0.0088 16.0 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 PAN domain Lectin_C PF00059.21 RUS73262.1 - 0.057 14.2 0.0 0.09 13.5 0.0 1.4 1 0 0 1 1 1 0 Lectin C-type domain AAA PF00004.29 RUS73263.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) XAP5 PF04921.14 RUS73263.1 - 0.076 12.8 1.4 0.14 11.9 1.4 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator AAA_22 PF13401.6 RUS73263.1 - 0.086 13.1 0.0 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain WDCP PF15390.6 RUS73263.1 - 0.089 11.2 0.8 0.14 10.5 0.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ResIII PF04851.15 RUS73263.1 - 0.12 12.4 0.2 1.8 8.5 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit UPF0102 PF02021.17 RUS73263.1 - 0.12 12.7 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 AAA_19 PF13245.6 RUS73263.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.16 RUS73263.1 - 1.1 8.7 2.8 2.4 7.6 2.2 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 DUF3886 PF13025.6 RUS73263.1 - 2 8.6 10.2 5.1 7.4 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Lyase_1 PF00206.20 RUS73264.1 - 9.1e-118 393.2 0.0 1.1e-117 392.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 RUS73264.1 - 4.6e-27 94.2 0.0 1.9e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus Ins145_P3_rec PF08709.11 RUS73265.1 - 2.1e-52 177.4 0.1 8.4e-52 175.5 0.1 1.8 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 RUS73265.1 - 2.3e-18 66.7 0.0 5.7e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 MIR domain Sortase PF04203.13 RUS73265.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Sortase domain Trp_leader1 PF08055.11 RUS73265.1 - 0.13 12.0 0.5 0.26 11.0 0.5 1.5 1 0 0 1 1 1 0 Tryptophan leader peptide MIR PF02815.19 RUS73266.1 - 2.1e-20 73.3 0.1 2.7e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 MIR domain Baculo_PEP_C PF04513.12 RUS73267.1 - 0.0013 18.8 1.1 0.044 13.8 1.8 2.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2046 PF09755.9 RUS73267.1 - 0.0039 16.5 0.1 0.0051 16.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ApoO PF09769.9 RUS73267.1 - 0.0046 16.9 0.4 0.013 15.5 0.5 1.7 1 1 0 1 1 1 1 Apolipoprotein O GLTP PF08718.11 RUS73267.1 - 0.0067 16.7 0.9 0.015 15.6 0.7 1.6 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) DNA_pack_C PF02499.15 RUS73267.1 - 0.0076 15.2 0.4 0.0096 14.9 0.4 1.2 1 0 0 1 1 1 1 Probable DNA packing protein, C-terminus Wap1 PF16997.5 RUS73267.1 - 0.015 14.5 2.0 0.021 14.0 1.8 1.3 1 1 0 1 1 1 0 Wap1 domain EF-hand_3 PF09069.11 RUS73267.1 - 0.017 15.5 0.3 0.039 14.3 0.2 1.7 1 1 0 1 1 1 0 EF-hand DUF4795 PF16043.5 RUS73267.1 - 0.051 13.2 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Lectin_C PF00059.21 RUS73268.1 - 3.7e-14 53.4 2.2 4.7e-14 53.0 2.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 RUS73268.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Fibrinogen_C PF00147.18 RUS73269.1 - 1.9e-54 184.8 4.1 3e-54 184.2 4.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain BLOC1_2 PF10046.9 RUS73269.1 - 2.1e-06 27.9 9.0 0.013 15.7 0.1 3.8 2 1 2 4 4 4 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 RUS73269.1 - 8.4e-06 26.2 5.8 0.022 15.2 0.1 3.2 1 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 RUS73269.1 - 1.9e-05 24.7 10.4 0.0027 17.7 1.6 2.9 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 RUS73269.1 - 2.8e-05 24.2 11.7 0.021 15.0 2.3 2.8 1 1 1 2 2 2 2 Haemolysin XhlA ABC_tran_CTD PF16326.5 RUS73269.1 - 0.00049 20.3 11.0 1.9 8.8 0.7 4.3 1 1 3 4 4 4 3 ABC transporter C-terminal domain Lge1 PF11488.8 RUS73269.1 - 0.0024 18.0 9.9 0.052 13.7 0.7 2.7 2 1 1 3 3 2 2 Transcriptional regulatory protein LGE1 Spc29 PF17082.5 RUS73269.1 - 0.0055 16.6 9.2 0.15 11.9 0.7 2.9 1 1 1 3 3 3 2 Spindle Pole Component 29 DUF3584 PF12128.8 RUS73269.1 - 0.0093 13.5 1.3 0.012 13.1 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PLAC9 PF15205.6 RUS73269.1 - 0.01 16.2 6.6 0.6 10.5 0.6 2.9 2 1 1 3 3 3 0 Placenta-specific protein 9 HSBP1 PF06825.12 RUS73269.1 - 0.014 15.2 17.3 1.3 8.9 0.7 4.2 1 1 2 3 3 3 0 Heat shock factor binding protein 1 DUF1394 PF07159.12 RUS73269.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) CLZ PF16526.5 RUS73269.1 - 0.023 15.0 13.8 0.82 10.1 1.6 4.5 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoO PF09769.9 RUS73269.1 - 0.052 13.5 0.5 0.15 12.0 0.4 1.8 1 1 0 1 1 1 0 Apolipoprotein O DUF2730 PF10805.8 RUS73269.1 - 0.069 13.2 6.6 3.8 7.7 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) GLTP PF08718.11 RUS73269.1 - 0.087 13.1 2.4 0.2 11.9 0.3 2.1 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) DHR10 PF18595.1 RUS73269.1 - 0.13 12.3 7.9 0.076 13.1 1.4 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain HrpB7 PF09486.10 RUS73269.1 - 0.14 12.6 0.5 23 5.4 0.0 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 RUS73269.1 - 0.2 11.7 10.3 1.9 8.6 3.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RUS73269.1 - 0.2 11.8 7.7 0.38 10.9 0.6 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2937 PF11157.8 RUS73269.1 - 0.22 11.2 0.2 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Prefoldin_2 PF01920.20 RUS73269.1 - 0.25 11.3 10.6 6.7 6.7 5.6 3.9 2 1 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 RUS73269.1 - 0.29 11.6 19.2 2 8.9 3.0 4.4 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4164 PF13747.6 RUS73269.1 - 0.46 10.8 7.6 14 6.1 7.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) RPW8 PF05659.11 RUS73269.1 - 0.71 9.6 10.0 0.87 9.3 1.1 2.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prominin PF05478.11 RUS73269.1 - 0.89 7.4 6.1 1.3 6.9 6.1 1.2 1 0 0 1 1 1 0 Prominin LXG PF04740.12 RUS73269.1 - 0.93 9.2 8.7 0.92 9.2 0.6 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily APG6_N PF17675.1 RUS73269.1 - 1.3 9.6 7.5 0.38 11.3 3.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 RUS73269.1 - 1.4 9.1 5.7 4.8 7.3 0.3 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4795 PF16043.5 RUS73269.1 - 1.6 8.3 14.0 6.9 6.2 14.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Not3 PF04065.15 RUS73269.1 - 2 7.8 9.0 0.58 9.5 2.0 2.2 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component FapA PF03961.13 RUS73269.1 - 2.4 6.7 8.3 0.6 8.6 3.4 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 RUS73269.1 - 3.1 7.9 11.7 2.9 8.0 1.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3552 PF12072.8 RUS73269.1 - 3.4 7.0 8.2 4.4 6.7 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Ead_Ea22 PF13935.6 RUS73269.1 - 5.9 7.5 8.3 12 6.6 0.9 2.6 2 1 0 2 2 2 0 Ead/Ea22-like protein Tropomyosin_1 PF12718.7 RUS73269.1 - 9.1 6.4 12.4 1.8 8.7 7.1 2.2 1 1 0 2 2 2 0 Tropomyosin like Ctr PF04145.15 RUS73270.1 - 5.4e-25 88.7 0.0 2.4e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.15 RUS73271.1 - 4.5e-32 111.7 4.4 1.2e-31 110.3 4.4 1.6 1 1 0 1 1 1 1 Ctr copper transporter family Acyl-CoA_dh_1 PF00441.24 RUS73272.1 - 3.3e-46 157.2 2.3 4.8e-46 156.7 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS73272.1 - 5.6e-26 90.6 0.1 1.4e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS73272.1 - 1.5e-25 90.1 0.0 2.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS73272.1 - 3.5e-20 72.6 2.8 5.2e-20 72.1 2.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RUS73272.1 - 5.4e-05 23.0 0.2 0.00035 20.3 0.2 2.3 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 RUS73273.1 - 2.2e-27 95.9 43.4 1.4e-26 93.3 35.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RXT2_N PF08595.11 RUS73274.1 - 0.049 13.7 4.6 0.25 11.4 0.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF1110 PF06533.12 RUS73275.1 - 0.046 13.7 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) CAC1F_C PF16885.5 RUS73276.1 - 2.7 7.6 14.3 0.18 11.4 8.9 1.7 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Chorion_2 PF03964.15 RUS73276.1 - 7.4 7.5 24.6 0.25 12.2 11.8 3.3 3 0 0 3 3 3 0 Chorion family 2 Bactofilin PF04519.13 RUS73277.1 - 0.0076 16.5 14.8 0.016 15.5 14.8 1.6 1 1 0 1 1 1 1 Polymer-forming cytoskeletal Usher_TcfC PF17271.2 RUS73277.1 - 0.29 9.9 7.1 0.92 8.2 2.8 2.0 1 1 1 2 2 2 0 TcfC Usher-like barrel domain SGP PF17228.2 RUS73277.1 - 0.86 10.5 5.2 6.5 7.7 5.2 2.0 1 1 0 1 1 1 0 Sulphur globule protein LppX_LprAFG PF07161.13 RUS73277.1 - 2.6 7.8 13.1 5.7e+02 0.2 13.1 2.2 1 1 0 1 1 1 0 LppX_LprAFG lipoprotein EF-hand_5 PF13202.6 RUS73278.1 - 3.8e-14 51.4 1.8 9.4e-07 28.1 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 RUS73278.1 - 2.1e-13 48.7 4.1 3.6e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS73278.1 - 5.5e-11 42.8 4.3 4.6e-07 30.2 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS73278.1 - 6.5e-11 41.2 1.8 0.0062 16.4 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RUS73278.1 - 0.00054 19.8 1.8 2.2 8.2 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS73278.1 - 0.0018 18.6 1.4 0.74 10.2 0.3 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RUS73278.1 - 0.019 15.2 3.3 0.19 12.0 0.6 2.9 2 1 1 3 3 3 0 Dockerin type I domain NRN1 PF15056.6 RUS73278.1 - 0.09 12.9 1.2 0.12 12.5 0.5 1.6 1 1 0 1 1 1 0 Neuritin protein family OMS28_porin PF03532.13 RUS73278.1 - 0.1 11.8 0.5 0.6 9.3 0.0 2.0 1 1 0 2 2 2 0 OMS28 porin Eno-Rase_FAD_bd PF07055.12 RUS73278.1 - 0.31 11.5 3.2 17 5.9 0.3 2.7 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain TPH PF13868.6 RUS73281.1 - 1.4e-74 250.7 148.5 1.4e-74 250.7 148.5 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain MFS_1 PF07690.16 RUS73283.1 - 5.2e-10 38.8 6.6 6.7e-10 38.4 6.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS73283.1 - 1.2e-08 34.3 4.3 1.4e-08 34.0 4.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 RUS73283.1 - 7.5e-05 21.3 1.3 8.7e-05 21.1 1.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 RUS73283.1 - 0.001 17.5 0.4 0.001 17.5 0.4 1.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 RUS73283.1 - 0.0011 17.9 3.6 0.0014 17.6 3.6 1.1 1 0 0 1 1 1 1 MFS_1 like family DNA_pol_A_exo1 PF01612.20 RUS73284.1 - 1.5e-46 158.3 1.0 3e-46 157.3 0.7 1.6 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 RUS73284.1 - 5.5e-22 78.3 0.4 1.5e-21 76.9 0.4 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HIRAN PF08797.11 RUS73284.1 - 0.038 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 HIRAN domain HRDC PF00570.23 RUS73284.1 - 0.089 12.8 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 HRDC domain P66_CC PF16563.5 RUS73284.1 - 0.29 10.8 2.4 11 5.8 0.2 2.7 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 7tm_1 PF00001.21 RUS73285.1 - 3.3e-05 23.4 17.4 5.5e-05 22.6 17.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 RUS73286.1 - 1.6e-05 24.0 3.2 2.1e-05 23.6 3.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS73287.1 - 2e-15 56.6 0.5 2.3e-15 56.4 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 RUS73287.1 - 0.0014 17.5 1.2 0.0015 17.5 1.2 1.1 1 0 0 1 1 1 1 POT family BT1 PF03092.16 RUS73287.1 - 0.086 11.1 0.8 0.1 10.8 0.8 1.1 1 0 0 1 1 1 0 BT1 family 7tm_1 PF00001.21 RUS73288.1 - 2.6e-08 33.5 11.8 2.6e-08 33.5 11.8 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS73288.1 - 5.2e-08 32.6 16.9 1.5e-07 31.1 16.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS73288.1 - 0.00032 20.4 20.1 0.00085 19.0 20.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 RUS73288.1 - 0.0011 18.6 10.2 0.0011 18.6 10.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Tmemb_9 PF05434.11 RUS73288.1 - 0.17 11.8 1.5 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 TMEM9 DUF3810 PF12725.7 RUS73288.1 - 9.5 5.5 7.9 4.3 6.6 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) RRM_5 PF13893.6 RUS73289.1 - 1.2e-18 66.9 0.4 2.5e-10 40.0 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RUS73289.1 - 4.9e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS73289.1 - 0.001 18.9 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF2682 PF10909.8 RUS73291.1 - 7.4 7.2 7.8 7.6 7.1 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2682) Somatomedin_B PF01033.17 RUS73292.1 - 0.00012 22.4 15.5 0.00012 22.4 15.5 2.0 2 0 0 2 2 2 1 Somatomedin B domain Minor_capsid_3 PF12691.7 RUS73292.1 - 0.08 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage F5_F8_type_C PF00754.25 RUS73293.1 - 7.1e-07 29.4 0.0 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain Y_phosphatase PF00102.27 RUS73294.1 - 7.5e-101 336.6 0.0 2.7e-67 226.8 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Adeno_E3_CR2 PF02439.15 RUS73294.1 - 0.0009 18.9 0.4 0.0017 18.0 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Y_phosphatase3 PF13350.6 RUS73294.1 - 0.0034 17.4 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RUS73294.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS73294.1 - 0.075 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Vpu PF00558.19 RUS73294.1 - 0.15 11.8 0.5 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Vpu protein SKG6 PF08693.10 RUS73294.1 - 3.8 7.0 6.1 8.7 5.9 6.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Spaetzle PF16077.5 RUS73295.1 - 0.015 15.8 0.0 0.056 14.0 0.0 2.0 1 1 0 1 1 1 0 Spaetzle R3H-assoc PF13902.6 RUS73296.1 - 4.4e-17 62.7 2.6 4.4e-17 62.7 2.6 1.6 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 RUS73296.1 - 1e-07 31.8 0.9 2.3e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 R3H domain DUF4070 PF13282.6 RUS73296.1 - 0.022 14.9 0.3 0.091 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Lectin_C PF00059.21 RUS73297.1 - 4.3e-15 56.4 0.3 6.2e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF5075 PF16825.5 RUS73297.1 - 0.026 14.2 0.1 0.077 12.7 0.0 1.7 1 1 1 2 2 2 0 IGP family C-type lectin domain F5_F8_type_C PF00754.25 RUS73298.1 - 0.0007 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain zf-C2H2_6 PF13912.6 RUS73299.1 - 0.00014 21.7 0.6 0.00043 20.2 0.6 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS73299.1 - 0.041 13.5 1.4 1.2 8.8 0.1 3.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain BolA PF01722.18 RUS73299.1 - 0.18 12.1 2.0 0.91 9.9 0.1 2.7 2 0 0 2 2 2 0 BolA-like protein GAGA PF09237.11 RUS73299.1 - 0.31 10.9 3.4 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 GAGA factor zf-met PF12874.7 RUS73299.1 - 0.48 10.9 4.0 1.5 9.3 0.7 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RUS73299.1 - 0.76 10.4 8.3 0.14 12.7 1.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73299.1 - 4.7 7.8 9.7 0.52 10.8 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS73299.1 - 5.5 8.1 10.0 0.13 13.2 1.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger SOGA PF11365.8 RUS73299.1 - 9.6 7.4 8.6 2.4 9.4 0.1 3.8 3 1 1 4 4 4 0 Protein SOGA zf-C2H2_4 PF13894.6 RUS73300.1 - 1.3e-06 28.8 10.6 0.046 14.6 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS73300.1 - 0.00012 22.3 15.6 0.11 13.0 2.2 4.1 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-met PF12874.7 RUS73300.1 - 0.0002 21.7 12.5 0.0043 17.4 3.2 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Spc7 PF08317.11 RUS73300.1 - 0.00025 20.1 32.7 0.025 13.5 16.2 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein zf_C2H2_ZHX PF18387.1 RUS73300.1 - 0.00029 20.4 7.2 0.011 15.4 0.3 3.5 4 0 0 4 4 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 RUS73300.1 - 0.0011 19.2 10.6 0.51 10.7 3.2 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Sec34 PF04136.15 RUS73300.1 - 0.0018 18.2 40.9 0.42 10.5 3.8 5.0 3 2 2 5 5 5 4 Sec34-like family Baculo_IE-1 PF05290.11 RUS73300.1 - 0.011 15.7 0.4 0.15 12.0 0.1 2.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) ATG16 PF08614.11 RUS73300.1 - 0.012 15.9 43.1 0.17 12.1 20.8 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 RUS73300.1 - 0.014 15.9 24.5 0.44 11.1 5.2 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Vps54_N PF10475.9 RUS73300.1 - 0.035 13.4 23.4 0.39 10.0 3.1 3.6 1 1 2 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex zf-C2H2_6 PF13912.6 RUS73300.1 - 0.042 13.9 7.5 0.69 10.0 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger I_LWEQ PF01608.17 RUS73300.1 - 0.066 13.4 46.6 1.6 9.0 12.0 3.7 2 1 1 3 3 3 0 I/LWEQ domain zf-MYST PF17772.1 RUS73300.1 - 0.1 12.2 1.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 MYST family zinc finger domain zf-BED PF02892.15 RUS73300.1 - 0.17 11.9 4.6 0.35 10.9 0.6 3.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 RUS73300.1 - 0.25 11.7 16.8 0.47 10.8 0.2 4.6 4 2 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-CCCH_7 PF18586.1 RUS73300.1 - 0.75 10.2 4.9 8 6.9 0.3 4.2 2 2 2 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 COG6 PF06419.11 RUS73300.1 - 1.2 7.3 32.0 0.81 7.8 6.4 3.5 2 2 2 4 4 4 0 Conserved oligomeric complex COG6 YabA PF06156.13 RUS73300.1 - 1.6 9.4 21.1 11 6.7 3.6 4.3 2 2 0 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 RUS73300.1 - 2.8 8.1 39.0 8.7 6.5 9.4 4.2 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 RUS73300.1 - 3.3 8.0 16.0 9.2 6.6 2.0 4.4 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Leu_zip PF15294.6 RUS73300.1 - 4.4 6.7 21.4 7.5 6.0 4.2 2.7 2 0 0 2 2 2 0 Leucine zipper MCPsignal PF00015.21 RUS73300.1 - 5.7 6.7 38.1 1.6 8.5 15.2 3.7 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3552 PF12072.8 RUS73300.1 - 5.7 6.3 25.5 8.4 5.8 1.3 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF3552) DUF2935 PF11155.8 RUS73300.1 - 7.2 7.0 10.3 27 5.1 1.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Vps5 PF09325.10 RUS73300.1 - 8 5.9 39.3 6.1 6.3 9.6 4.4 2 2 2 4 4 4 0 Vps5 C terminal like DUF948 PF06103.11 RUS73300.1 - 8.4 6.7 28.2 8.1 6.8 3.2 4.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.13 RUS73300.1 - 8.9 5.4 30.8 4.4 6.4 14.8 2.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Transferrin PF00405.17 RUS73301.1 - 5e-136 453.2 0.0 2.4e-77 260.3 0.0 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 RUS73301.1 - 5.7e-08 32.7 0.0 0.0016 18.1 0.0 2.7 2 1 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4911 PF16256.5 RUS73303.1 - 0.011 15.7 9.0 1.8 8.6 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4911) Fringe PF02434.16 RUS73304.1 - 6e-11 42.2 0.7 2.8e-10 40.0 0.1 2.1 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 RUS73304.1 - 0.0015 18.4 0.2 0.13 12.0 0.1 2.7 2 1 1 3 3 3 2 Galactosyltransferase Laminin_G_2 PF02210.24 RUS73305.1 - 3.3e-08 34.2 0.7 5.8e-08 33.4 0.7 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS73305.1 - 0.0033 17.6 0.2 1.4 9.1 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Homeodomain PF00046.29 RUS73306.1 - 3.9e-23 81.1 4.2 8.7e-23 79.9 4.2 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS73306.1 - 0.0022 17.8 0.4 0.0068 16.2 0.4 1.8 1 0 0 1 1 1 1 OAR domain Forkhead PF00250.18 RUS73307.1 - 1.6e-35 121.2 0.0 3.6e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Forkhead PF00250.18 RUS73308.1 - 0.0057 16.9 0.6 0.013 15.8 0.6 1.5 1 0 0 1 1 1 1 Forkhead domain Solute_trans_a PF03619.16 RUS73309.1 - 5.2e-87 291.7 14.5 6.2e-87 291.5 14.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BK_channel_a PF03493.18 RUS73310.1 - 1.9e-35 121.0 0.0 5.1e-35 119.6 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 RUS73310.1 - 2.6e-17 62.9 18.6 6.1e-17 61.7 18.6 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS73310.1 - 3.4e-15 55.8 1.7 3.4e-15 55.8 1.7 3.5 4 0 0 4 4 4 1 Ion channel TrkA_N PF02254.18 RUS73310.1 - 0.0013 19.0 0.0 0.015 15.6 0.0 2.4 3 0 0 3 3 3 1 TrkA-N domain Lig_chan PF00060.26 RUS73310.1 - 0.0023 17.8 0.3 0.0023 17.8 0.3 2.3 2 0 0 2 2 2 1 Ligand-gated ion channel Ni_hydr_CYTB PF01292.20 RUS73310.1 - 0.051 13.2 6.3 0.18 11.3 0.3 2.6 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4718 PF15842.5 RUS73310.1 - 0.14 11.9 0.4 0.33 10.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) zf-HIT PF04438.16 RUS73311.1 - 2e-09 37.2 12.1 5e-09 35.9 12.1 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 RUS73311.1 - 0.89 9.7 9.9 0.25 11.4 5.7 2.2 1 1 1 2 2 2 0 MYND finger KaiB PF07689.12 RUS73313.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.0 5 0 0 5 5 5 0 KaiB domain ENOD93 PF03386.14 RUS73313.1 - 2.6 8.0 7.9 15 5.5 0.4 3.2 2 1 1 3 3 3 0 Early nodulin 93 ENOD93 protein DTHCT PF08070.11 RUS73313.1 - 7.8 7.3 74.9 0.33 11.7 21.8 4.3 1 1 3 5 5 5 0 DTHCT (NUC029) region SRP40_C PF05022.12 RUS73314.1 - 1.1e-29 103.1 1.8 3.6e-29 101.4 1.8 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain ENOD93 PF03386.14 RUS73314.1 - 0.9 9.5 10.4 7.9 6.4 0.1 4.8 5 0 0 5 5 5 0 Early nodulin 93 ENOD93 protein HSP20 PF00011.21 RUS73315.1 - 3.9e-19 68.7 0.3 4.8e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS73315.1 - 0.00052 19.5 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Cadherin_pro PF08758.11 RUS73315.1 - 0.0093 16.1 0.1 0.022 14.9 0.1 1.7 1 1 0 1 1 1 1 Cadherin prodomain like CS PF04969.16 RUS73315.1 - 0.069 14.2 0.1 0.13 13.2 0.1 1.5 1 0 0 1 1 1 0 CS domain HSP20 PF00011.21 RUS73316.1 - 1.3e-19 70.2 0.5 1.4e-19 70.1 0.5 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS73316.1 - 0.004 16.7 0.0 0.0074 15.8 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cadherin_pro PF08758.11 RUS73316.1 - 0.041 14.1 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Cadherin prodomain like HSP70 PF00012.20 RUS73317.1 - 2.2e-215 716.4 2.3 2.6e-215 716.2 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS73317.1 - 1.4e-15 56.9 0.0 2.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RUS73317.1 - 0.00026 20.8 0.0 0.0012 18.6 0.0 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain DHDPS PF00701.22 RUS73318.1 - 6.2e-22 77.6 0.0 5e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family AA_permease_2 PF13520.6 RUS73319.1 - 0.093 11.5 28.2 0.12 11.1 28.2 1.1 1 0 0 1 1 1 0 Amino acid permease CBP_BcsG PF11658.8 RUS73319.1 - 1.1 7.6 3.7 1.3 7.3 3.7 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF2070 PF09843.9 RUS73319.1 - 6.4 4.9 21.9 7.9 4.6 21.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SspK PF08176.12 RUS73322.1 - 0.00028 21.1 1.5 0.58 10.5 0.0 3.2 3 0 0 3 3 3 2 Small acid-soluble spore protein K family GCR1_C PF12550.8 RUS73322.1 - 0.0077 16.5 2.0 3.4 8.1 0.1 2.3 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes RTA1 PF04479.13 RUS73324.1 - 1.9 8.0 5.8 2.8 7.5 5.8 1.1 1 0 0 1 1 1 0 RTA1 like protein AdoHcyase_NAD PF00670.21 RUS73326.1 - 5.1e-79 264.0 1.1 6.8e-79 263.6 1.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 RUS73326.1 - 8.1e-57 192.6 0.0 5e-54 183.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 RUS73326.1 - 3.7e-08 32.9 0.0 5.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RUS73326.1 - 9.8e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 RUS73326.1 - 0.00012 21.4 0.4 0.00054 19.3 0.4 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RUS73326.1 - 0.0097 16.0 0.2 0.034 14.2 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 RUS73326.1 - 0.023 15.0 0.1 0.058 13.6 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 RUS73326.1 - 0.024 15.1 0.2 0.055 13.9 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 RUS73326.1 - 0.025 14.3 0.7 0.83 9.3 0.1 2.1 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 RUS73326.1 - 0.032 13.5 0.4 0.11 11.8 0.4 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Prolactin_RP PF15172.6 RUS73327.1 - 0.072 12.7 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Prolactin-releasing peptide US6 PF17616.2 RUS73328.1 - 0.029 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Viral unique short region 6 RESP18 PF14948.6 RUS73328.1 - 0.045 14.1 0.7 0.4 11.0 0.1 2.5 2 1 0 2 2 2 0 RESP18 domain Kringle PF00051.18 RUS73331.1 - 1.4e-08 34.9 7.9 5.2e-08 33.1 7.9 2.0 1 0 0 1 1 1 1 Kringle domain Lectin_C PF00059.21 RUS73331.1 - 8.5e-06 26.5 0.5 2.9e-05 24.7 0.5 2.0 1 0 0 1 1 1 1 Lectin C-type domain Sushi PF00084.20 RUS73331.1 - 0.00015 22.3 6.3 0.0021 18.6 0.2 3.8 3 0 0 3 3 3 1 Sushi repeat (SCR repeat) CUB_2 PF02408.20 RUS73331.1 - 0.0056 16.4 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 CUB-like domain CUB PF00431.20 RUS73331.1 - 0.0073 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 CUB domain Astacin PF01400.24 RUS73332.1 - 1.5e-18 67.1 0.1 5.2e-18 65.4 0.1 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) ApeC PF16977.5 RUS73332.1 - 5.4e-08 33.0 0.8 3.8e-06 27.0 0.1 2.9 2 1 0 3 3 3 1 C-terminal domain of apextrin Lem_TRP PF08262.11 RUS73333.1 - 0.00021 20.9 2.7 2.3e+02 2.2 0.0 6.6 7 0 0 7 7 7 0 Leucophaea maderae tachykinin-related peptide CPSase_sm_chain PF00988.22 RUS73333.1 - 0.001 18.9 5.1 11 5.8 0.8 4.8 1 1 3 4 4 4 2 Carbamoyl-phosphate synthase small chain, CPSase domain PglD_N PF17836.1 RUS73333.1 - 0.0027 18.3 0.0 5.7 7.7 0.0 3.0 1 1 1 2 2 2 2 PglD N-terminal domain DUF4573 PF15140.6 RUS73334.1 - 0.00092 19.1 0.0 0.087 12.6 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) TMEM154 PF15102.6 RUS73337.1 - 0.094 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4084 PF13321.6 RUS73337.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) CDC27 PF09507.10 RUS73343.1 - 0.0025 17.3 38.7 0.003 17.0 38.7 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Nop25 PF09805.9 RUS73343.1 - 0.095 13.2 47.9 0.16 12.4 47.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SID-1_RNA_chan PF13965.6 RUS73343.1 - 0.099 11.0 3.0 0.095 11.1 3.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 RUS73343.1 - 0.29 9.9 25.9 0.38 9.5 25.9 1.1 1 0 0 1 1 1 0 Presenilin FGF-BP1 PF06473.12 RUS73343.1 - 1 9.1 28.5 1.6 8.5 28.5 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Cellulose_synt PF03552.14 RUS73343.1 - 1.2 7.5 15.2 1.9 6.9 15.2 1.3 1 0 0 1 1 1 0 Cellulose synthase CNDH2_C PF16858.5 RUS73343.1 - 2.2 8.1 32.6 3.1 7.6 32.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MAJIN PF15077.6 RUS73343.1 - 3.9 7.2 22.0 5.4 6.7 22.0 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4569 PF15133.6 RUS73343.1 - 5.6 6.6 20.5 7.3 6.2 20.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Ank_5 PF13857.6 RUS73344.1 - 7.2e-09 35.8 0.7 3.7e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS73344.1 - 1.1e-08 35.4 0.1 3.1e-08 34.0 0.1 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS73344.1 - 2.7e-08 34.3 0.0 4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS73344.1 - 3.1e-08 33.7 0.1 7.6e-05 23.0 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RUS73344.1 - 8.3e-08 31.9 0.0 0.014 15.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat CBM_14 PF01607.24 RUS73345.1 - 6.3e-18 64.7 29.8 2.7e-11 43.4 5.6 3.9 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain LURAP PF14854.6 RUS73346.1 - 0.00022 21.1 0.0 0.00089 19.2 0.0 2.1 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF3504 PF12012.8 RUS73347.1 - 6.7e-60 201.7 0.4 6.7e-60 201.7 0.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3504) zf-FCS PF06467.14 RUS73347.1 - 7.5e-14 51.4 73.2 1.9e-06 27.7 5.7 8.5 8 0 0 8 8 8 6 MYM-type Zinc finger with FCS sequence motif YHS PF04945.13 RUS73347.1 - 0.067 13.3 0.2 0.067 13.3 0.2 6.1 8 0 0 8 8 8 0 YHS domain DUF3330 PF11809.8 RUS73347.1 - 0.13 12.3 26.7 0.15 12.1 1.0 6.2 3 2 1 5 5 5 0 Domain of unknown function (DUF3330) RRM_1 PF00076.22 RUS73348.1 - 5.2e-29 99.9 0.7 6.8e-15 54.6 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 RUS73348.1 - 2.5e-25 88.4 5.2 6.1e-25 87.2 4.8 1.9 2 0 0 2 2 2 1 NOPS (NUC059) domain RRM_7 PF16367.5 RUS73348.1 - 0.013 15.6 0.0 0.096 12.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 RUS73348.1 - 0.059 13.4 9.4 0.27 11.3 0.0 3.5 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 RUS73348.1 - 0.15 12.0 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF812 PF05667.11 RUS73349.1 - 0.18 10.7 1.4 22 3.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) COX6B PF02297.17 RUS73349.1 - 3.2 8.0 7.7 67 3.8 1.9 3.4 2 1 0 3 3 3 0 Cytochrome oxidase c subunit VIb ORMDL PF04061.14 RUS73350.1 - 0.053 13.3 0.3 0.064 13.1 0.3 1.2 1 0 0 1 1 1 0 ORMDL family 7tm_1 PF00001.21 RUS73351.1 - 2.5e-08 33.6 17.0 4.3e-08 32.8 17.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73351.1 - 1.1e-06 28.5 13.7 1.1e-06 28.5 13.7 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3169 PF11368.8 RUS73351.1 - 0.0014 18.2 2.0 0.0014 18.2 2.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) TMEM208_SND2 PF05620.11 RUS73351.1 - 0.3 10.9 3.7 8 6.2 0.2 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 PL48 PF15903.5 RUS73353.1 - 0.15 11.0 3.4 0.16 10.9 3.4 1.0 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 Acetyltransf_1 PF00583.25 RUS73354.1 - 5.8e-05 23.3 0.2 8.4e-05 22.8 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4698 PF15769.5 RUS73355.1 - 1.2e-17 64.2 0.2 1.6e-17 63.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) GCIP PF13324.6 RUS73355.1 - 0.081 12.5 0.5 0.081 12.5 0.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2076 PF09849.9 RUS73355.1 - 0.19 11.7 13.4 0.27 11.3 13.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 RUS73355.1 - 1.7 7.9 20.1 2.4 7.4 20.1 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 RUS73355.1 - 2.3 7.6 9.6 2.8 7.3 9.6 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RUS73355.1 - 2.3 8.0 7.1 3.3 7.5 7.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4698 PF15769.5 RUS73356.1 - 9.4e-08 31.6 13.5 0.00027 20.2 3.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4698) Gemini_coat PF00844.18 RUS73356.1 - 0.25 10.7 3.5 0.68 9.4 2.2 2.0 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family SpoIIIAH PF12685.7 RUS73356.1 - 2.3 8.0 14.7 4.2 7.1 14.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3429 PF11911.8 RUS73357.1 - 3.8e-31 108.3 8.2 4.8e-31 108.0 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) STIL_N PF15253.6 RUS73358.1 - 9.4e-98 327.8 3.5 9.7e-98 327.7 0.0 2.6 2 0 0 2 2 2 1 SCL-interrupting locus protein N-terminus ADK PF00406.22 RUS73359.1 - 9.5e-43 145.9 0.0 1.2e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RUS73359.1 - 4.3e-35 121.1 0.0 5.9e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS73359.1 - 6.1e-08 33.3 0.1 4.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS73359.1 - 0.0022 18.2 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 RUS73359.1 - 0.0041 16.8 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Thermopsin PF05317.11 RUS73359.1 - 0.052 13.0 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Thermopsin Zeta_toxin PF06414.12 RUS73359.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin MaoC_dehydratas PF01575.19 RUS73360.1 - 4.5e-10 39.2 0.1 1.5e-09 37.5 0.1 1.9 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydratas PF01575.19 RUS73361.1 - 6.9e-18 64.4 0.2 2.9e-09 36.5 0.0 3.1 2 1 1 3 3 3 2 MaoC like domain LapA_dom PF06305.11 RUS73361.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vac_ImportDeg PF09783.9 RUS73361.1 - 0.11 12.3 0.2 7.8 6.3 0.0 3.3 3 1 0 3 3 3 0 Vacuolar import and degradation protein TMEM138 PF14935.6 RUS73361.1 - 0.17 12.5 0.3 0.92 10.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 138 Choline_transpo PF04515.12 RUS73362.1 - 3.2e-69 233.6 21.2 3.2e-69 233.6 21.2 2.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter CrgA PF06781.12 RUS73362.1 - 0.046 13.8 6.2 0.44 10.6 0.4 3.8 3 1 0 3 3 3 0 Cell division protein CrgA DUF1218 PF06749.12 RUS73362.1 - 0.053 14.0 20.3 0.19 12.2 2.1 5.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1218) SPC25 PF06703.11 RUS73362.1 - 0.075 12.8 9.2 1.1 9.0 0.9 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1616 PF07760.11 RUS73362.1 - 0.11 11.9 13.7 0.14 11.6 10.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF3483 PF11982.8 RUS73362.1 - 0.11 12.1 4.5 0.27 10.8 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Prominin PF05478.11 RUS73362.1 - 0.34 8.8 10.5 1.1 7.1 4.3 2.4 2 0 0 2 2 2 0 Prominin KRE9 PF05390.11 RUS73363.1 - 0.24 12.1 2.7 0.47 11.2 1.0 2.2 1 1 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Ank_5 PF13857.6 RUS73364.1 - 4.7e-32 109.6 3.8 2.2e-09 37.4 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS73364.1 - 2.8e-27 95.1 3.1 3.4e-09 37.2 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS73364.1 - 1.9e-22 79.4 1.0 4.6e-05 23.9 0.0 5.9 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS73364.1 - 2.7e-16 59.2 9.1 5.1e-05 23.5 0.1 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 RUS73364.1 - 5.8e-14 50.8 3.5 0.0005 20.3 0.0 8.3 8 1 0 8 8 8 2 Ankyrin repeat DUF5423 PF17461.2 RUS73364.1 - 0.14 11.0 5.1 0.027 13.3 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5423) DNA_pol_phi PF04931.13 RUS73365.1 - 3.6 5.6 18.6 4.9 5.1 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS73365.1 - 7.9 4.9 9.7 11 4.4 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.14 RUS73367.1 - 0.014 15.8 18.5 0.019 15.4 18.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Neur_chan_memb PF02932.16 RUS73367.1 - 0.074 13.1 7.6 0.077 13.0 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 RUS73367.1 - 0.09 11.2 1.2 0.091 11.2 1.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 RUS73367.1 - 0.22 9.7 21.6 0.25 9.6 21.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 RUS73367.1 - 0.26 11.6 29.0 0.43 10.8 29.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RPOL_N PF14700.6 RUS73367.1 - 0.27 10.6 21.6 0.34 10.2 21.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal AAA_23 PF13476.6 RUS73367.1 - 0.37 11.3 28.5 0.46 11.0 28.5 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 RUS73367.1 - 0.46 10.3 29.8 0.19 11.6 27.9 1.4 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 RUS73367.1 - 0.53 10.0 21.9 0.62 9.8 21.9 1.1 1 0 0 1 1 1 0 AAA domain SRP-alpha_N PF04086.13 RUS73367.1 - 0.55 10.1 33.1 0.86 9.5 33.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3527 PF12043.8 RUS73367.1 - 0.68 9.4 17.2 0.84 9.1 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) SLC12 PF03522.15 RUS73367.1 - 0.79 8.7 21.3 0.91 8.5 21.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 RUS73367.1 - 0.8 9.8 16.9 1 9.4 16.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 RUS73367.1 - 1.2 9.3 13.9 1.6 8.8 13.9 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.12 RUS73367.1 - 1.4 9.2 30.3 2.3 8.5 30.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 RUS73367.1 - 1.4 8.9 61.2 2.7 8.0 61.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Endostatin PF06482.11 RUS73367.1 - 1.5 8.2 13.0 2 7.8 13.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5427 PF10310.9 RUS73367.1 - 2.1 7.2 21.8 2.4 7.0 21.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Rtf2 PF04641.12 RUS73367.1 - 2.5 7.4 40.9 4.1 6.7 40.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.10 RUS73367.1 - 2.8 8.3 42.8 3.8 7.8 42.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 RUS73367.1 - 2.9 7.9 43.1 4.7 7.2 43.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Tim54 PF11711.8 RUS73367.1 - 3.2 6.5 25.3 4.2 6.1 25.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5308 PF17233.2 RUS73367.1 - 3.6 7.8 6.7 5 7.3 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) NPR3 PF03666.13 RUS73367.1 - 5.7 5.6 29.6 7.9 5.1 29.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 RUS73367.1 - 5.7 5.8 12.2 6.7 5.6 12.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TMEM214 PF10151.9 RUS73367.1 - 6.9 5.0 30.5 10 4.4 30.5 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 RUS73367.1 - 6.9 5.3 18.5 9.1 4.9 18.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 RUS73367.1 - 7.8 6.9 16.3 11 6.3 16.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) ALMT PF11744.8 RUS73367.1 - 8.1 5.2 17.5 10 4.8 17.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 RUS73367.1 - 9.2 5.4 13.4 14 4.8 13.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.15 RUS73367.1 - 9.4 6.8 7.8 14 6.3 7.8 1.4 1 0 0 1 1 1 0 Ctr copper transporter family VIR_N PF15912.5 RUS73367.1 - 9.5 5.7 11.2 12 5.4 11.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SDA1 PF05285.12 RUS73369.1 - 0.0021 17.6 26.6 0.0034 16.9 26.6 1.4 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 RUS73369.1 - 0.0045 15.3 22.0 0.0061 14.9 22.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF913 PF06025.12 RUS73369.1 - 0.0049 15.9 1.7 0.0066 15.5 1.7 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Nop14 PF04147.12 RUS73369.1 - 0.0089 14.3 26.9 0.012 13.9 26.9 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4820 PF16091.5 RUS73369.1 - 0.012 15.0 2.4 0.019 14.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cwf_Cwc_15 PF04889.12 RUS73369.1 - 0.019 14.7 26.7 0.031 14.0 24.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 RUS73369.1 - 0.024 14.3 11.9 0.046 13.4 11.9 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC27 PF09507.10 RUS73369.1 - 0.061 12.7 12.8 0.085 12.2 12.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mpp10 PF04006.12 RUS73369.1 - 0.074 11.5 25.9 0.11 11.0 25.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.6 RUS73369.1 - 0.16 11.9 13.7 0.29 11.1 13.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.12 RUS73369.1 - 0.19 11.5 10.5 0.3 10.9 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 RUS73369.1 - 0.23 10.2 9.8 0.29 9.9 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 RUS73369.1 - 0.33 10.5 25.6 0.55 9.8 25.6 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 RUS73369.1 - 0.57 9.5 23.0 0.82 8.9 23.0 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.8 RUS73369.1 - 0.69 8.6 10.1 1.1 7.9 10.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.13 RUS73369.1 - 1.4 7.8 20.8 1.9 7.4 20.8 1.2 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 RUS73369.1 - 2.1 8.6 14.3 4.2 7.7 14.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 RUS73369.1 - 3 6.5 9.9 4.3 6.0 9.9 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 RUS73369.1 - 3.1 6.9 12.8 0.75 9.0 9.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3381 PF11861.8 RUS73369.1 - 5.3 6.8 22.7 9.5 6.0 22.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YL1 PF05764.13 RUS73369.1 - 7.5 6.6 34.2 14 5.7 34.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_M13_N PF05649.13 RUS73370.1 - 3.5e-51 175.1 6.2 4.4e-51 174.7 6.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS73370.1 - 1.8e-29 102.8 0.0 4.4e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M13 DUF1542 PF07564.11 RUS73370.1 - 0.0048 17.0 2.2 0.0088 16.1 2.2 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) Herpes_LMP2 PF07415.11 RUS73370.1 - 0.22 10.2 0.4 0.33 9.7 0.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Cor1 PF04803.12 RUS73371.1 - 1.9e-44 151.1 34.8 1.9e-44 151.1 34.8 1.6 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region SF-assemblin PF06705.11 RUS73371.1 - 0.0092 15.4 24.3 0.21 10.9 12.3 2.1 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF3584 PF12128.8 RUS73371.1 - 0.028 11.9 24.7 0.035 11.7 24.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PTCB-BRCT PF12738.7 RUS73371.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain FUSC PF04632.12 RUS73371.1 - 0.67 8.4 9.2 0.75 8.3 9.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family 7tm_3 PF00003.22 RUS73373.1 - 1.1e-55 189.0 17.4 1.5e-55 188.6 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 RUS73373.1 - 0.056 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region 2-oxoacid_dh PF00198.23 RUS73374.1 - 2.9e-79 265.8 0.8 6.2e-79 264.7 0.8 1.5 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 RUS73374.1 - 3.3e-12 46.5 0.1 7e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Pox_D3 PF04580.13 RUS73374.1 - 0.0062 16.2 0.0 0.0087 15.7 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein ECH_1 PF00378.20 RUS73375.1 - 1.7e-49 168.4 0.1 1.9e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS73375.1 - 8.4e-23 81.4 0.4 2.2e-21 76.7 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HTH_47 PF16221.5 RUS73375.1 - 0.066 12.8 0.1 0.22 11.1 0.1 1.8 1 1 0 1 1 1 0 winged helix-turn-helix Methyltransf_16 PF10294.9 RUS73376.1 - 2.7e-38 131.4 0.0 3.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RUS73376.1 - 0.047 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain C12orf66_like PF09404.10 RUS73377.1 - 3.4e-36 125.1 0.4 5.1e-36 124.5 0.4 1.3 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like C12orf66_like PF09404.10 RUS73378.1 - 5.6e-59 200.1 0.7 6.7e-59 199.9 0.7 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like ParcG PF10274.9 RUS73379.1 - 0.06 13.5 0.2 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein DUF3169 PF11368.8 RUS73380.1 - 0.00079 19.0 0.5 0.00079 19.0 0.5 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3169) DUF3341 PF11821.8 RUS73380.1 - 0.033 13.8 5.3 1.7 8.2 2.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Peptidase_A17 PF05380.13 RUS73381.1 - 4.3e-11 43.1 0.0 8.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase O-antigen_lig PF13425.6 RUS73381.1 - 0.013 14.3 0.2 0.016 14.0 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein G-patch PF01585.23 RUS73382.1 - 2.1e-11 43.5 3.8 5.2e-11 42.3 3.8 1.7 1 0 0 1 1 1 1 G-patch domain ABC_tran PF00005.27 RUS73383.1 - 2.7e-13 50.6 0.0 3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 RUS73383.1 - 0.0036 17.4 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 RUS73383.1 - 0.016 15.3 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 RUS73383.1 - 0.087 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 RUS73383.1 - 0.09 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 RUS73383.1 - 0.14 11.9 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 RUS73383.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 RUS73383.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 RUS73383.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 RUS73383.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 RUS73383.1 - 0.18 11.0 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glyco_transf_92 PF01697.27 RUS73384.1 - 1.2e-32 113.6 0.0 1.7e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS73384.1 - 3.3e-05 24.3 0.0 5.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 LRR_RI_capping PF18779.1 RUS73384.1 - 0.22 11.2 0.3 0.62 9.8 0.0 1.8 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat MgsA_C PF12002.8 RUS73385.1 - 5.1e-56 189.2 0.0 7.7e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 RUS73385.1 - 4e-23 81.6 0.1 8.9e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 RUS73385.1 - 1.2e-08 34.8 0.1 0.004 16.9 0.0 2.7 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 RUS73385.1 - 1.6e-06 28.5 1.3 0.0027 18.1 0.0 3.0 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS73385.1 - 0.00017 21.3 0.0 0.0018 18.0 0.0 2.1 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 RUS73385.1 - 0.00046 20.2 0.4 0.1 12.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RUS73385.1 - 0.0028 17.1 0.1 0.66 9.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AsmA_1 PF13109.6 RUS73385.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region PDZ PF00595.24 RUS73386.1 - 1.7e-11 44.3 0.1 3e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS73386.1 - 9.7e-09 34.9 0.1 3.8e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PB1 PF00564.24 RUS73386.1 - 1.6e-08 34.4 0.1 4e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 PB1 domain SNF PF00209.18 RUS73387.1 - 1.2e-190 634.7 39.2 3.6e-190 633.1 39.2 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family SH3_1 PF00018.28 RUS73389.1 - 3.5e-08 32.9 0.1 6.2e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS73389.1 - 1.4e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PTB PF08416.13 RUS73389.1 - 4e-05 23.8 0.0 0.00018 21.7 0.0 2.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_3 PF08239.11 RUS73389.1 - 0.0003 21.0 0.1 0.00057 20.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_9 PF14604.6 RUS73389.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 RUS73389.1 - 0.024 15.1 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_10 PF17902.1 RUS73389.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 SH3 domain zf-dskA_traR PF01258.17 RUS73389.1 - 0.15 12.0 3.5 1.6e+02 2.4 0.0 4.3 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger 7TM_GPCR_Srx PF10328.9 RUS73390.1 - 1.3e-06 28.3 13.9 1.3e-06 28.3 13.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS73390.1 - 0.034 13.4 27.7 2.1 7.5 27.7 2.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw COPIIcoated_ERV PF07970.12 RUS73391.1 - 3.6e-47 161.0 0.2 6e-47 160.3 0.0 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RUS73391.1 - 1.1e-24 86.6 0.1 2.3e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RRM_1 PF00076.22 RUS73392.1 - 0.0043 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TerB_C PF15615.6 RUS73392.1 - 0.027 14.8 0.3 0.033 14.5 0.3 1.1 1 0 0 1 1 1 0 TerB-C domain ARS2 PF04959.13 RUS73393.1 - 5.3 7.4 14.6 6.2 7.2 14.6 1.0 1 0 0 1 1 1 0 Arsenite-resistance protein 2 rRNA_processing PF08524.11 RUS73394.1 - 4.5e-18 65.7 28.5 5.8e-18 65.3 28.5 1.2 1 0 0 1 1 1 1 rRNA processing Glyco_transf_7N PF13733.6 RUS73395.1 - 1.3e-45 154.4 0.5 2.4e-45 153.5 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS73395.1 - 1.9e-24 85.1 0.7 3.4e-24 84.3 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Cellulase PF00150.18 RUS73395.1 - 0.0071 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PhoQ_Sensor PF08918.10 RUS73395.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor CRAL_TRIO PF00650.20 RUS73396.1 - 7.2e-18 64.8 0.1 1.1e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RUS73396.1 - 0.00017 21.7 0.2 0.00032 20.8 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AXE1 PF05448.12 RUS73396.1 - 0.027 13.2 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) P5CR_dimer PF14748.6 RUS73399.1 - 6.5e-41 138.8 1.5 1.9e-40 137.3 0.5 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 RUS73399.1 - 1.5e-18 67.1 0.2 3e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RUS73399.1 - 6.7e-06 26.4 0.8 0.0003 21.0 0.2 2.3 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 RUS73399.1 - 9.4e-05 21.5 0.8 0.00019 20.5 0.8 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 RUS73399.1 - 0.00011 22.2 0.6 0.00074 19.5 0.6 2.0 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 RUS73399.1 - 0.0036 17.4 0.3 0.0065 16.5 0.3 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 RUS73399.1 - 0.0056 16.1 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 RUS73399.1 - 0.08 13.2 0.1 0.3 11.3 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 RUS73399.1 - 0.62 9.9 4.0 4 7.3 0.2 2.4 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApoO PF09769.9 RUS73400.1 - 1e-20 74.0 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O YtxH PF12732.7 RUS73400.1 - 0.89 10.1 0.0 0.89 10.1 0.0 2.6 3 1 0 3 3 3 0 YtxH-like protein IBR PF01485.21 RUS73401.1 - 1.7e-05 24.9 6.2 1.7e-05 24.9 6.2 2.5 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain F-box-like PF12937.7 RUS73401.1 - 0.00025 20.9 0.4 0.00099 19.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS73401.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain CEBP_ZZ PF16366.5 RUS73401.1 - 0.13 12.6 7.7 0.36 11.1 7.7 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PTH2 PF01981.16 RUS73404.1 - 8.5e-35 119.6 0.1 1.1e-34 119.2 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.31 RUS73404.1 - 9.7e-09 35.0 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF1335 PF07056.11 RUS73404.1 - 0.048 13.8 0.1 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) zf-H2C2_2 PF13465.6 RUS73405.1 - 4.7e-80 260.7 106.3 2.3e-09 37.2 1.2 16.9 17 0 0 17 17 17 14 Zinc-finger double domain zf-C2H2 PF00096.26 RUS73405.1 - 3.6e-63 206.7 131.4 1.2e-05 25.4 0.5 16.1 16 0 0 16 16 16 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS73405.1 - 6.1e-51 166.7 126.4 0.0012 19.5 0.3 16.1 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS73405.1 - 3.1e-16 58.9 114.9 0.0046 16.9 1.9 16.4 16 1 0 16 16 16 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS73405.1 - 7.1e-11 42.1 61.0 0.93 9.9 0.2 15.6 16 0 0 16 16 16 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS73405.1 - 3.7e-10 39.8 92.5 0.13 12.7 0.3 15.6 16 0 0 16 16 16 8 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS73405.1 - 1.2e-08 34.9 60.6 0.092 12.9 0.6 10.3 9 3 2 11 11 11 6 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RUS73405.1 - 6e-07 30.1 42.6 0.61 10.9 0.5 8.0 2 1 3 7 7 7 5 zinc-ribbon family zf-Di19 PF05605.12 RUS73405.1 - 6.3e-07 29.6 68.4 0.11 12.8 1.6 9.8 5 2 4 10 10 10 6 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RUS73405.1 - 9.3e-07 28.3 59.4 0.025 14.2 0.1 14.3 15 0 0 15 15 15 4 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 RUS73405.1 - 0.00083 19.8 5.9 0.0095 16.4 2.3 12.9 3 2 11 14 14 13 2 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 RUS73405.1 - 0.0016 19.1 27.5 9.6 7.0 0.0 10.6 4 4 6 11 11 11 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 RUS73405.1 - 0.0086 16.1 44.7 0.5 10.4 1.3 8.0 2 1 4 6 6 6 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 RUS73405.1 - 0.013 15.5 2.6 0.013 15.5 2.6 9.7 6 4 4 10 10 9 0 Transposase zinc-ribbon domain DUF45 PF01863.17 RUS73405.1 - 0.019 15.0 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-C2H2_11 PF16622.5 RUS73405.1 - 0.44 10.4 72.3 0.33 10.8 1.7 13.1 13 0 0 13 13 13 0 zinc-finger C2H2-type ADK_lid PF05191.14 RUS73405.1 - 0.73 9.9 41.0 3.1 7.9 0.6 9.2 6 3 2 8 8 8 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 RUS73405.1 - 0.81 10.4 53.7 0.12 13.0 1.2 10.6 1 1 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 RUS73405.1 - 4.3 7.7 77.5 2.6 8.4 1.9 13.9 1 1 11 12 12 12 0 C2H2 type zinc-finger (2 copies) SQS_PSY PF00494.19 RUS73406.1 - 0.019 14.5 0.1 0.023 14.2 0.1 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase PBP1_TM PF14812.6 RUS73407.1 - 0.0015 18.8 2.6 0.0015 18.8 2.6 2.8 2 1 1 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_1 PF00076.22 RUS73408.1 - 1.3e-30 105.0 0.1 3.9e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Es2 PF09751.9 RUS73408.1 - 0.0014 18.4 0.2 0.0019 18.0 0.2 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PHM7_cyt PF14703.6 RUS73408.1 - 0.043 14.1 0.9 0.11 12.7 0.4 1.8 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MSP1_C PF07462.11 RUS73409.1 - 0.014 14.2 1.5 0.016 13.9 1.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCHC_6 PF15288.6 RUS73410.1 - 0.00064 19.5 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle LptF_LptG PF03739.14 RUS73411.1 - 0.25 10.1 4.8 1.2 7.9 0.4 2.5 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG bZIP_1 PF00170.21 RUS73412.1 - 7.7e-07 29.1 14.4 1.7e-06 28.1 14.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor FliD_N PF02465.18 RUS73412.1 - 0.026 15.2 2.6 0.026 15.2 2.6 3.5 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus bZIP_2 PF07716.15 RUS73412.1 - 0.058 13.5 16.9 0.17 12.0 16.9 1.8 1 1 0 1 1 1 0 Basic region leucine zipper DUF730 PF05325.11 RUS73412.1 - 0.22 11.6 3.1 0.39 10.7 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) bZIP_Maf PF03131.17 RUS73412.1 - 0.92 10.1 9.6 2.6 8.6 9.6 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4280 PF14107.6 RUS73412.1 - 3.5 8.5 6.5 2 9.2 3.7 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4280) UPF0242 PF06785.11 RUS73412.1 - 5 7.2 13.8 9.6 6.3 13.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_72 PF03198.14 RUS73413.1 - 0.095 11.9 0.5 0.14 11.4 0.5 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Rhodanese PF00581.20 RUS73414.1 - 2.4e-25 89.1 0.0 8.4e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain FA_desaturase PF00487.24 RUS73415.1 - 3.6e-12 46.7 11.3 4.6e-12 46.3 11.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase ubiquitin PF00240.23 RUS73416.1 - 7.9e-17 60.8 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 RUS73416.1 - 9.6e-10 38.5 9.3 2.4e-09 37.2 9.3 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 RUS73416.1 - 0.00071 20.0 0.0 0.0022 18.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RUS73416.1 - 0.0024 17.7 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Na_H_Exchanger PF00999.21 RUS73417.1 - 3.6e-28 98.4 29.6 3.6e-28 98.4 29.6 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4148 PF13663.6 RUS73417.1 - 0.12 12.6 0.0 0.65 10.2 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Tn7_Tnp_TnsA_N PF08722.11 RUS73418.1 - 0.0011 19.1 0.7 39 4.5 0.1 5.4 1 1 2 3 3 3 0 TnsA endonuclease N terminal gp37_C PF12604.8 RUS73418.1 - 0.0037 17.0 0.4 24 4.6 0.0 3.9 1 1 4 5 5 5 1 Tail fibre protein gp37 C terminal TPR_3 PF07720.12 RUS73418.1 - 0.044 13.8 0.7 1.1e+02 3.0 0.0 5.5 10 2 1 11 11 11 0 Tetratricopeptide repeat VirB3 PF05101.13 RUS73418.1 - 0.2 11.9 13.0 68 3.8 0.3 6.1 1 1 6 7 7 7 0 Type IV secretory pathway, VirB3-like protein MALT1_Ig PF18703.1 RUS73418.1 - 0.33 10.9 1.9 59 3.7 0.1 3.1 1 1 2 3 3 3 0 MALT1 Ig-like domain MarB PF13999.6 RUS73418.1 - 0.4 10.5 10.4 92 3.0 0.1 5.6 1 1 8 9 9 9 0 MarB protein Na_H_Exchanger PF00999.21 RUS73419.1 - 5e-13 48.6 13.0 5e-13 48.6 13.0 2.6 1 1 2 3 3 3 2 Sodium/hydrogen exchanger family Sad1_UNC PF07738.13 RUS73420.1 - 6.2e-37 126.6 0.0 1.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ADAM_CR PF08516.12 RUS73420.1 - 0.069 13.6 1.1 0.19 12.1 0.6 2.0 2 0 0 2 2 2 0 ADAM cysteine-rich VWD PF00094.25 RUS73421.1 - 0.00025 21.3 22.8 0.036 14.3 5.7 2.7 1 1 1 2 2 2 2 von Willebrand factor type D domain FtsK_alpha PF17854.1 RUS73421.1 - 0.002 18.2 0.3 0.028 14.5 0.0 2.3 1 1 0 2 2 2 1 FtsK alpha domain NID PF07292.13 RUS73421.1 - 4.2 8.1 23.9 14 6.4 4.9 4.7 1 1 2 3 3 3 0 Nmi/IFP 35 domain (NID) LicD PF04991.13 RUS73423.1 - 6.4e-14 52.6 4.2 1.6e-06 28.5 2.8 2.2 1 1 1 2 2 2 2 LicD family Cornifin PF02389.15 RUS73424.1 - 3.4e-05 24.0 0.0 0.2 11.8 0.0 2.1 1 1 1 2 2 2 2 Cornifin (SPRR) family EcsC PF12787.7 RUS73424.1 - 0.0017 18.1 0.1 0.49 10.0 0.1 2.8 1 1 0 1 1 1 1 EcsC protein family Fibrinogen_BP PF08017.11 RUS73424.1 - 0.078 11.4 0.0 0.085 11.3 0.0 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein Nucleoporin_N PF08801.11 RUS73425.1 - 5e-98 328.7 0.0 7.4e-98 328.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 RUS73425.1 - 7.6e-31 107.5 1.3 2.2e-30 106.0 1.1 1.7 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal ERAP1_C PF11838.8 RUS73425.1 - 0.088 12.3 6.9 0.05 13.2 0.3 3.0 2 1 0 3 3 3 0 ERAP1-like C-terminal domain Pkinase_Tyr PF07714.17 RUS73427.1 - 1.1e-71 241.1 0.0 2e-71 240.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS73427.1 - 2.2e-35 122.3 0.0 4.1e-35 121.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS73427.1 - 3e-11 43.2 0.0 6.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 RUS73427.1 - 1.5e-10 40.7 0.0 3.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS73427.1 - 1.6e-09 37.2 0.9 6e-09 35.4 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RUS73427.1 - 7e-05 22.4 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 RUS73427.1 - 0.00065 18.7 0.2 0.0032 16.5 0.2 1.9 1 1 0 1 1 1 1 Haspin like kinase domain RRM_1 PF00076.22 RUS73428.1 - 2.2e-16 59.4 0.0 1.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS73428.1 - 5.3e-05 22.8 0.0 0.0007 19.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS73428.1 - 0.048 13.5 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Phosducin PF02114.16 RUS73429.1 - 9.9e-68 227.9 5.8 1.2e-66 224.3 5.8 2.0 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 RUS73429.1 - 0.00024 21.1 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AAA_12 PF13087.6 RUS73430.1 - 7.8e-47 159.5 0.0 1.8e-46 158.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain S1-like PF14444.6 RUS73430.1 - 2.6e-29 100.9 0.9 5.9e-11 42.1 0.0 3.5 3 0 0 3 3 3 3 S1-like AAA_11 PF13086.6 RUS73430.1 - 6.3e-29 101.6 0.1 1.4e-13 51.3 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 RUS73430.1 - 1.2e-12 47.9 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS73430.1 - 7e-11 42.7 0.0 8.2e-09 35.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 RUS73430.1 - 0.00054 19.6 0.0 0.0076 15.8 0.0 2.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 RUS73430.1 - 0.00091 18.7 0.0 0.004 16.6 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 RUS73430.1 - 0.0025 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C PF13361.6 RUS73430.1 - 0.0026 17.2 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 RUS73430.1 - 0.012 15.8 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CSD PF00313.22 RUS73430.1 - 0.05 13.5 2.5 0.54 10.1 0.1 2.6 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain AAA PF00004.29 RUS73430.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS73430.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RUS73430.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Arm_2 PF04826.13 RUS73431.1 - 1.6e-17 63.9 0.0 4e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 Armadillo-like WD40 PF00400.32 RUS73432.1 - 5.5e-61 201.1 16.4 3.7e-08 33.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73432.1 - 1.6e-19 70.0 0.1 4.4e-06 26.9 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS73432.1 - 2.5e-10 39.8 2.2 0.058 12.3 0.1 6.0 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS73432.1 - 8.6e-09 35.5 1.6 2.8e-06 27.4 0.1 3.3 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RUS73432.1 - 0.00033 20.1 0.1 1.2 8.4 0.0 3.9 3 1 0 3 3 3 2 WD40-like domain Frtz PF11768.8 RUS73432.1 - 0.0015 17.0 0.0 0.014 13.7 0.0 2.1 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 RUS73432.1 - 0.025 13.9 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Methyltransf_25 PF13649.6 RUS73432.1 - 0.049 14.3 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Med11 PF10280.9 RUS73432.1 - 0.13 12.7 0.8 0.27 11.7 0.8 1.5 1 0 0 1 1 1 0 Mediator complex protein Isy1 PF06246.12 RUS73433.1 - 2.1e-96 322.4 3.6 2.8e-96 322.0 3.6 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Xpo1 PF08389.12 RUS73434.1 - 1.9e-36 125.4 0.0 1.9e-36 125.4 0.0 3.3 4 1 1 5 5 5 1 Exportin 1-like protein DUF4404 PF14357.6 RUS73434.1 - 0.073 13.7 0.2 0.82 10.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Flot PF15975.5 RUS73435.1 - 0.0077 16.4 6.0 0.0077 16.4 6.0 2.1 1 1 1 2 2 2 1 Flotillin VGCC_beta4Aa_N PF12052.8 RUS73435.1 - 3.9 7.7 7.0 30 4.8 2.9 3.2 2 1 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal RecA_dep_nuc PF16786.5 RUS73436.1 - 0.17 12.0 0.3 0.5 10.5 0.0 1.7 2 0 0 2 2 2 0 Recombination enhancement, RecA-dependent nuclease zf-C2H2 PF00096.26 RUS73437.1 - 3.2e-20 71.4 83.5 0.00019 21.7 1.2 10.2 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73437.1 - 4.6e-18 64.7 68.2 2.4e-05 24.6 3.2 10.4 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS73437.1 - 3.8e-16 58.4 79.5 0.0019 18.9 2.3 10.6 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS73437.1 - 1.2e-13 50.6 61.5 3.1e-05 23.6 1.1 10.0 10 0 0 10 10 10 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS73437.1 - 3.7e-05 23.9 24.7 0.14 12.5 0.8 7.0 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS73437.1 - 0.0023 18.2 52.4 0.18 12.2 2.5 6.8 2 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding Tom37 PF10568.9 RUS73437.1 - 0.0027 18.0 0.6 0.0052 17.1 0.6 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein zf-C2H2_6 PF13912.6 RUS73437.1 - 0.0031 17.5 0.2 0.0031 17.5 0.2 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS73437.1 - 0.0063 16.1 0.1 0.0063 16.1 0.1 7.5 4 2 4 8 8 8 4 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 RUS73437.1 - 0.82 10.2 0.0 0.82 10.2 0.0 8.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type DUF899 PF05988.12 RUS73437.1 - 1 8.9 4.3 6.5 6.2 0.6 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF899) zf-CCHC PF00098.23 RUS73439.1 - 5.1e-05 23.2 1.4 5.1e-05 23.2 1.4 2.0 2 0 0 2 2 2 1 Zinc knuckle Phage_int_SAM_6 PF18644.1 RUS73439.1 - 0.004 17.2 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 Phage integrase SAM-like domain zf-CCHC_4 PF14392.6 RUS73439.1 - 0.011 15.4 1.0 0.021 14.6 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF719 PF05334.13 RUS73439.1 - 0.013 15.7 1.1 0.026 14.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Suf PF05843.14 RUS73439.1 - 0.38 10.7 12.6 0.73 9.8 12.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 RUS73439.1 - 0.4 10.9 9.6 0.95 9.7 9.6 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA U1snRNP70_N PF12220.8 RUS73439.1 - 0.64 10.7 13.5 0.41 11.3 1.2 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal eIF-3_zeta PF05091.12 RUS73439.1 - 2.2 7.1 14.9 2.9 6.8 14.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Baculo_PP31 PF05311.11 RUS73439.1 - 8.3 5.8 8.0 13 5.2 8.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Presenilin PF01080.17 RUS73439.1 - 9.8 4.8 11.7 14 4.3 11.7 1.1 1 0 0 1 1 1 0 Presenilin Phage_int_SAM_6 PF18644.1 RUS73440.1 - 0.0014 18.6 0.0 0.0038 17.3 0.0 1.6 2 0 0 2 2 2 1 Phage integrase SAM-like domain Retrotrans_gag PF03732.17 RUS73440.1 - 0.019 15.2 0.3 0.053 13.8 0.3 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein PNMA PF14893.6 RUS73440.1 - 0.027 13.9 0.8 0.032 13.6 0.1 1.4 2 0 0 2 2 2 0 PNMA DUF1759 PF03564.15 RUS73440.1 - 0.069 13.1 0.4 1.3 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) zf-CCHC PF00098.23 RUS73441.1 - 9.7e-10 38.1 10.1 0.00018 21.4 2.2 2.6 2 0 0 2 2 2 2 Zinc knuckle Cep57_CLD_2 PF14197.6 RUS73441.1 - 0.0033 17.5 5.0 0.0082 16.2 5.0 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 zf-CCHC_4 PF14392.6 RUS73441.1 - 0.013 15.2 12.2 0.072 12.8 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle ATG16 PF08614.11 RUS73441.1 - 0.073 13.3 7.7 0.18 12.0 7.7 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2937 PF11157.8 RUS73441.1 - 0.15 11.8 2.8 0.27 10.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) KxDL PF10241.9 RUS73441.1 - 0.18 12.1 3.7 0.18 12.1 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Ndc1_Nup PF09531.10 RUS73441.1 - 0.2 10.3 0.9 0.29 9.8 0.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5327 PF17261.2 RUS73441.1 - 0.5 11.1 4.2 0.19 12.5 1.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CTU2 PF10288.9 RUS73441.1 - 1.6 9.0 6.2 3.4 7.9 0.8 2.6 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-CCHC_2 PF13696.6 RUS73441.1 - 2.9 7.8 6.6 0.45 10.4 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 RUS73441.1 - 3.4 7.4 13.8 1.6 8.5 3.8 3.0 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger PID PF00640.23 RUS73442.1 - 1.3e-42 145.1 3.3 1.6e-41 141.6 0.1 2.6 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 RUS73442.1 - 7.7e-27 93.5 4.8 2.6e-13 50.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RUS73442.1 - 3.3e-15 55.7 0.7 2.1e-06 27.4 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS73442.1 - 0.0051 17.1 0.0 0.057 13.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 RUS73442.1 - 0.02 14.9 0.6 0.063 13.3 0.0 2.1 2 0 0 2 2 2 0 Rhomboid N-terminal domain Syndecan PF01034.20 RUS73443.1 - 0.0014 18.5 0.4 0.0032 17.4 0.4 1.6 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 RUS73443.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.11 RUS73443.1 - 0.014 15.5 3.9 0.11 12.6 0.2 2.6 2 0 0 2 2 2 0 Podoplanin DUF2970 PF11174.8 RUS73443.1 - 0.016 15.1 3.9 0.019 14.8 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) EphA2_TM PF14575.6 RUS73443.1 - 0.022 15.6 0.0 0.061 14.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 RUS73443.1 - 0.092 13.7 1.0 0.76 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Collectrin PF16959.5 RUS73443.1 - 0.14 12.0 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Renal amino acid transporter SKG6 PF08693.10 RUS73443.1 - 2 7.9 10.2 3.7 7.0 10.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-RRN7 PF11781.8 RUS73444.1 - 0.052 13.2 1.8 0.14 11.8 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 BtpA PF03437.15 RUS73445.1 - 5.7e-61 206.2 3.8 7.2e-61 205.8 3.8 1.0 1 0 0 1 1 1 1 BtpA family His_biosynth PF00977.21 RUS73445.1 - 0.031 13.8 0.2 0.098 12.1 0.1 1.9 1 1 0 2 2 2 0 Histidine biosynthesis protein PUF PF00806.19 RUS73446.1 - 1.5e-20 71.6 5.6 0.0045 16.6 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Pentapeptide_4 PF13599.6 RUS73447.1 - 0.0034 17.5 0.0 0.63 10.3 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DDA1 PF10172.9 RUS73447.1 - 4.9 7.5 17.0 28 5.1 0.4 4.2 1 1 5 6 6 6 0 Det1 complexing ubiquitin ligase Thioredoxin PF00085.20 RUS73448.1 - 7.2e-09 35.6 0.1 1.4e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RUS73448.1 - 5.4e-06 25.5 0.2 7.1e-06 25.2 0.2 1.1 1 0 0 1 1 1 1 Phosducin Helveticin_J PF17312.2 RUS73448.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriocin helveticin-J Baculo_LEF-11 PF06385.12 RUS73448.1 - 0.72 10.4 3.9 9.6 6.8 1.4 2.5 2 1 0 2 2 2 0 Baculovirus LEF-11 protein Helicase_C_2 PF13307.6 RUS73449.1 - 3.8e-56 189.9 0.0 7.8e-56 188.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 RUS73449.1 - 8.1e-33 113.5 0.1 1.7e-32 112.5 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 RUS73449.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Helical and beta-bridge domain Acylphosphatase PF00708.18 RUS73449.1 - 0.082 13.3 0.0 1.3 9.5 0.0 2.7 2 1 1 3 3 3 0 Acylphosphatase DEAD_2 PF06733.15 RUS73450.1 - 5.3e-06 26.2 0.0 5.3e-06 26.2 0.0 1.9 2 1 0 2 2 2 1 DEAD_2 AAA_11 PF13086.6 RUS73450.1 - 0.00023 21.1 2.2 0.00029 20.7 2.2 1.1 1 0 0 1 1 1 1 AAA domain SEO_C PF14577.6 RUS73450.1 - 0.0018 17.7 1.5 0.0032 16.9 0.9 1.7 2 0 0 2 2 2 1 Sieve element occlusion C-terminus DUF4404 PF14357.6 RUS73450.1 - 0.051 14.2 1.6 0.051 14.2 1.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Ac76 PF05814.11 RUS73450.1 - 0.099 12.7 0.5 0.28 11.2 0.5 1.8 1 0 0 1 1 1 0 Orf76 (Ac76) ResIII PF04851.15 RUS73450.1 - 0.56 10.2 4.1 4.3 7.3 4.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PIEZO PF15917.5 RUS73450.1 - 4 6.9 13.5 4.3 6.7 12.8 1.3 1 1 0 1 1 1 0 Piezo CCDC158 PF15921.5 RUS73451.1 - 5.7e-54 183.4 114.3 1.6e-38 132.3 93.7 3.2 3 0 0 3 3 3 3 Coiled-coil domain-containing protein 158 CENP-F_leu_zip PF10473.9 RUS73451.1 - 0.0058 16.7 12.7 0.0058 16.7 12.7 11.4 3 2 9 12 12 12 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 RUS73451.1 - 0.011 15.9 3.8 0.011 15.9 3.8 10.2 9 2 1 11 11 11 0 Basic region leucine zipper Strep_SA_rep PF06696.11 RUS73451.1 - 0.49 10.5 2.6 2.2 8.3 2.6 2.2 1 0 0 1 1 1 0 Streptococcal surface antigen repeat PikAIV_N PF18605.1 RUS73452.1 - 2.8 7.6 9.1 0.29 10.8 3.4 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CBS PF00571.28 RUS73453.1 - 8.3e-16 58.2 0.4 9.6e-09 35.6 0.1 2.2 2 0 0 2 2 2 2 CBS domain DUF3792 PF12670.7 RUS73454.1 - 3.2 7.9 13.2 0.032 14.4 2.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) YvrJ PF12841.7 RUS73455.1 - 0.039 13.5 0.6 0.072 12.6 0.6 1.5 1 0 0 1 1 1 0 YvrJ protein family ADH_zinc_N PF00107.26 RUS73456.1 - 5.3e-21 74.9 0.0 1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS73456.1 - 4.2e-09 37.6 0.0 7.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS73456.1 - 2.7e-07 30.4 0.0 1.2e-06 28.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS73456.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase KCNQ_channel PF03520.14 RUS73457.1 - 2.4e-26 92.8 6.5 2.4e-26 92.8 6.5 2.8 1 1 1 2 2 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 RUS73457.1 - 1.7e-25 89.7 15.1 2.6e-25 89.1 15.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS73457.1 - 4.5e-12 45.8 9.0 4.5e-12 45.8 9.0 2.5 2 0 0 2 2 2 1 Ion channel DUF4746 PF15928.5 RUS73457.1 - 0.11 11.9 7.2 0.17 11.3 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3340 PF11818.8 RUS73457.1 - 0.18 11.9 14.7 0.45 10.7 14.7 1.6 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) PRKG1_interact PF15898.5 RUS73457.1 - 0.78 10.7 23.0 2.1 9.3 0.1 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4149 PF13664.6 RUS73457.1 - 1.5 9.2 6.3 1 9.7 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) TERB2 PF15101.6 RUS73457.1 - 2.2 8.3 14.3 4.5 7.3 14.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CD225 PF04505.12 RUS73457.1 - 3.8 7.7 6.5 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Interferon-induced transmembrane protein TFIIA PF03153.13 RUS73457.1 - 5.3 6.9 34.0 0.89 9.5 28.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 RUS73457.1 - 5.9 7.3 14.5 10 6.5 14.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4407 PF14362.6 RUS73457.1 - 6.3 6.1 12.7 16 4.7 12.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PP_M1 PF03012.14 RUS73458.1 - 0.063 12.8 0.2 0.063 12.8 0.2 1.5 2 0 0 2 2 2 0 Phosphoprotein Presenilin PF01080.17 RUS73458.1 - 3.1 6.5 3.6 3.7 6.2 3.6 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 RUS73458.1 - 8.1 5.7 9.0 11 5.2 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein ArgoL1 PF08699.10 RUS73459.1 - 0.14 11.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Argonaute linker 1 domain DUF4816 PF16086.5 RUS73460.1 - 0.39 10.7 41.0 1.8e+04 -28.2 41.0 6.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) ApbA_C PF08546.11 RUS73461.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Consortin_C PF15281.6 RUS73461.1 - 4.7 7.2 5.2 1 9.4 0.1 2.4 3 1 1 4 4 4 0 Consortin C-terminus DNA_pol_phi PF04931.13 RUS73463.1 - 3.1 5.8 6.8 3.4 5.7 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1647 PF07801.11 RUS73465.1 - 5.7e-07 29.4 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) IMS PF00817.20 RUS73466.1 - 1e-38 132.7 0.0 2e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RUS73466.1 - 1e-12 48.8 0.0 2.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.7 RUS73466.1 - 4.7e-10 39.3 0.0 9.7e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 RUS73466.1 - 7.6e-10 39.1 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RUS73466.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RUS73466.1 - 3.2e-06 27.3 0.0 6.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 RUS73466.1 - 4.6e-06 26.6 0.0 1.5e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif Cdd1 PF11731.8 RUS73466.1 - 0.082 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 RUS73466.1 - 0.09 13.1 0.1 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) mCpol PF18182.1 RUS73466.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Ank_2 PF12796.7 RUS73468.1 - 3.7e-22 78.7 0.5 2.5e-11 44.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS73468.1 - 7.9e-12 45.2 0.6 1.5e-08 34.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS73468.1 - 1.5e-10 41.0 0.1 6.3e-06 26.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS73468.1 - 2.1e-10 40.9 0.0 8.1e-07 29.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS73468.1 - 1.6e-05 24.9 0.3 0.018 15.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat ubiquitin PF00240.23 RUS73468.1 - 2.5e-05 23.9 0.1 5.7e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RUS73468.1 - 0.00041 20.7 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF4207 PF13904.6 RUS73468.1 - 0.0026 17.5 21.8 0.02 14.6 21.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4207) 7tm_1 PF00001.21 RUS73469.1 - 3.2e-29 102.1 17.8 3.8e-29 101.8 14.2 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73469.1 - 0.0017 18.1 12.6 0.0017 18.1 12.6 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS73469.1 - 0.012 15.3 7.4 0.19 11.5 2.0 3.1 3 0 0 3 3 3 0 Olfactory receptor DUF3899 PF13038.6 RUS73469.1 - 0.072 13.6 1.3 2.7 8.6 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF4834 PF16118.5 RUS73469.1 - 0.49 11.4 3.4 21 6.2 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Sulfotransfer_2 PF03567.14 RUS73470.1 - 1.2e-23 84.3 8.6 1e-20 74.7 4.1 2.3 2 0 0 2 2 2 2 Sulfotransferase family zf-H2C2_5 PF13909.6 RUS73471.1 - 1.4e-41 139.8 217.1 9.7e-10 38.0 1.0 28.1 29 0 0 29 29 29 19 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RUS73471.1 - 2.2e-08 34.1 246.4 0.0042 17.5 0.5 29.8 31 0 0 31 31 31 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73471.1 - 3e-06 27.4 5.3 3.7e-05 24.0 1.5 31.8 35 0 0 35 35 35 11 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RUS73471.1 - 0.04 14.6 56.7 0.26 12.0 0.5 12.1 11 3 3 14 14 14 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 RUS73471.1 - 2.4 9.2 241.9 0.089 13.7 1.2 30.6 32 0 0 32 32 32 0 C2H2-type zinc finger Ank_2 PF12796.7 RUS73472.1 - 3.6e-43 146.1 16.4 9e-15 55.0 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS73472.1 - 4.9e-37 125.8 18.8 4.4e-10 39.9 0.1 8.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS73472.1 - 4.1e-36 121.9 28.4 1.7e-05 25.0 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 RUS73472.1 - 6.2e-32 109.3 15.8 2.9e-09 37.0 0.3 6.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS73472.1 - 1.3e-30 102.0 13.4 0.0098 16.3 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat VPS9 PF02204.18 RUS73472.1 - 1.8e-13 50.6 0.0 4.8e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Thymosin PF01290.20 RUS73472.1 - 0.017 14.8 0.6 5.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Thymosin beta-4 family zinc_ribbon_9 PF14369.6 RUS73472.1 - 0.019 15.2 0.1 0.059 13.6 0.1 1.9 1 0 0 1 1 1 0 zinc-ribbon TCR PF03638.15 RUS73472.1 - 4.1 7.8 13.0 2.1 8.7 2.8 2.6 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF416 PF04222.12 RUS73473.1 - 0.022 14.2 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Solute_trans_a PF03619.16 RUS73473.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 Organic solute transporter Ostalpha ARID PF01388.21 RUS73474.1 - 2.2e-16 60.3 0.0 3.4e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CsrA PF02599.16 RUS73476.1 - 1.1e-17 63.7 26.0 1.9 8.5 0.2 12.0 1 1 16 17 17 17 17 Global regulator protein family ATP-synt_ab_N PF02874.23 RUS73476.1 - 1.9e-17 63.5 58.4 1 9.9 2.2 14.1 1 1 15 16 16 16 16 ATP synthase alpha/beta family, beta-barrel domain TGBp3 PF02495.17 RUS73476.1 - 1.4e-15 56.7 57.0 65 3.3 0.0 23.7 25 0 0 25 25 25 0 Triple gene block 3 FAM47 PF14642.6 RUS73476.1 - 3e-12 46.6 7.0 0.036 13.6 0.1 4.1 1 1 1 4 4 4 4 FAM47 family SspH PF08141.12 RUS73476.1 - 5.7e-06 26.4 22.6 6.5 7.0 0.1 6.9 1 1 6 8 8 8 6 Small acid-soluble spore protein H family Glyco_hydro_79C PF16862.5 RUS73476.1 - 8.5e-05 23.4 16.0 1.8e+04 -3.4 16.0 6.0 1 1 0 1 1 0 0 Glycosyl hydrolase family 79 C-terminal beta domain Ub-Mut7C PF14451.6 RUS73476.1 - 0.00067 19.4 34.7 7.3 6.5 0.5 9.1 1 1 19 20 20 20 6 Mut7-C ubiquitin ProQ_C PF17516.2 RUS73476.1 - 0.0086 15.5 51.0 13 5.3 0.7 12.0 1 1 17 18 18 18 3 ProQ C-terminal domain Phage_holin_3_5 PF16085.5 RUS73476.1 - 0.011 15.9 15.8 29 4.8 0.4 6.4 1 1 4 5 5 5 0 Bacteriophage holin Hol, superfamily III Ribosomal_L19 PF01245.20 RUS73476.1 - 0.13 12.2 36.5 48 3.9 0.6 10.1 1 1 13 14 14 14 0 Ribosomal protein L19 RNase_P_Rpp14 PF01900.19 RUS73476.1 - 9.6 6.5 24.7 3.8e+02 1.4 0.2 9.4 1 1 2 3 3 3 0 Rpp14/Pop5 family YEATS PF03366.16 RUS73478.1 - 3.5e-25 87.8 0.2 6.1e-25 87.0 0.2 1.4 1 0 0 1 1 1 1 YEATS family Neur_chan_memb PF02932.16 RUS73478.1 - 0.23 11.5 7.1 0.27 11.3 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 RUS73478.1 - 0.79 8.5 23.1 0.94 8.3 23.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyoxalase_4 PF13669.6 RUS73479.1 - 7.5e-21 74.5 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 RUS73479.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 RUS73479.1 - 2.5e-05 24.4 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 RUS73479.1 - 0.00018 21.4 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Phosphodiest PF01663.22 RUS73480.1 - 8.4e-12 45.3 0.2 1.5e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 RUS73480.1 - 3.9e-05 23.1 0.4 7.1e-05 22.3 0.4 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 RUS73480.1 - 3.9e-05 23.2 0.1 6.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF2207 PF09972.9 RUS73480.1 - 0.0015 17.4 0.2 0.0015 17.4 0.2 2.8 3 1 1 4 4 4 1 Predicted membrane protein (DUF2207) YfhO PF09586.10 RUS73480.1 - 0.061 11.6 11.7 0.14 10.4 11.7 1.5 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Mod_r PF07200.13 RUS73480.1 - 0.069 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1129 PF06570.11 RUS73480.1 - 0.076 12.5 5.9 2 7.9 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Glyco_hydro_30 PF02055.16 RUS73481.1 - 6.4e-148 492.4 0.2 8.1e-148 492.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 RUS73481.1 - 5e-14 52.3 2.4 5e-14 52.3 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 RUS73481.1 - 3.2e-07 29.9 0.0 5.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 LTD PF00932.19 RUS73481.1 - 0.056 13.8 0.1 9.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Lamin Tail Domain Thyroglob_assoc PF16597.5 RUS73482.1 - 0.018 15.4 0.3 0.13 12.6 0.1 2.5 2 0 0 2 2 2 0 Thyroglobulin_1 repeat associated disordered domain Aminotran_3 PF00202.21 RUS73483.1 - 3.8e-120 401.2 0.0 4.5e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III TB2_DP1_HVA22 PF03134.19 RUS73484.1 - 7.6e-20 70.6 8.9 1.2e-19 70.0 8.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family KASH_CCD PF14662.6 RUS73484.1 - 0.025 14.4 2.2 0.041 13.7 2.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH AAA_lid_1 PF17857.1 RUS73485.1 - 0.045 14.0 0.4 12 6.2 0.1 3.1 1 1 2 3 3 3 0 AAA+ lid domain DUF1131 PF06572.12 RUS73486.1 - 0.14 11.8 0.2 8.2 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1131) Stirrup PF09061.6 RUS73487.1 - 0.1 12.8 0.4 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 Stirrup Laminin_G_2 PF02210.24 RUS73488.1 - 4.2e-09 37.1 0.1 8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS73488.1 - 2.5e-06 27.7 0.1 4.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 RUS73488.1 - 0.0044 17.2 0.3 0.0083 16.3 0.3 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CD52 PF15116.6 RUS73489.1 - 0.0055 16.7 34.4 0.45 10.6 0.8 7.9 1 1 8 9 9 9 5 CAMPATH-1 antigen Asp5 PF17000.5 RUS73489.1 - 0.13 12.4 6.1 28 4.9 0.2 5.0 1 1 6 7 7 7 0 Accessory secretory protein Sec, Asp5 Defensin_beta PF00711.19 RUS73489.1 - 0.2 11.7 15.9 38 4.4 0.1 6.0 2 1 3 6 6 6 0 Beta defensin BUD22 PF09073.10 RUS73490.1 - 0.0019 17.6 40.8 0.0019 17.6 40.8 2.2 2 0 0 2 2 1 1 BUD22 TFIIA PF03153.13 RUS73490.1 - 0.0077 16.3 14.8 0.0077 16.3 14.8 3.1 2 1 1 3 3 1 1 Transcription factor IIA, alpha/beta subunit DUF4228 PF14009.6 RUS73490.1 - 0.022 15.2 7.7 0.096 13.1 8.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) RNA_pol_3_Rpc31 PF11705.8 RUS73490.1 - 0.022 15.0 44.6 0.022 15.0 44.6 4.6 2 1 0 2 2 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_11 PF13086.6 RUS73490.1 - 0.11 12.3 18.2 0.16 11.7 18.2 1.3 1 0 0 1 1 1 0 AAA domain Endostatin PF06482.11 RUS73490.1 - 0.44 10.0 8.8 0.56 9.6 8.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 RUS73490.1 - 0.47 8.8 7.2 0.87 7.9 7.2 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rtf2 PF04641.12 RUS73490.1 - 0.63 9.4 31.9 1.1 8.6 31.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CLN3 PF02487.17 RUS73490.1 - 0.92 8.5 10.6 1.5 7.8 10.6 1.5 1 0 0 1 1 1 0 CLN3 protein Spore_coat_CotO PF14153.6 RUS73490.1 - 3.4 7.6 36.1 0.64 9.9 32.3 1.7 2 0 0 2 2 2 0 Spore coat protein CotO Rgp1 PF08737.10 RUS73490.1 - 6.8 5.7 15.8 8.3 5.5 15.8 1.1 1 0 0 1 1 1 0 Rgp1 FancD2 PF14631.6 RUS73490.1 - 7.4 3.8 23.8 10 3.4 23.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Presenilin PF01080.17 RUS73490.1 - 9.3 4.9 33.6 0.37 9.5 23.7 2.0 2 0 0 2 2 2 0 Presenilin EGF PF00008.27 RUS73491.1 - 8.8e-67 220.9 215.2 1.6e-09 37.9 6.1 15.8 15 0 0 15 15 15 14 EGF-like domain hEGF PF12661.7 RUS73491.1 - 1.4e-43 146.0 191.1 2.5e-08 34.2 5.9 17.8 18 0 0 18 18 18 14 Human growth factor-like EGF EGF_CA PF07645.15 RUS73491.1 - 1e-28 99.2 211.5 1e-06 28.8 4.7 15.0 10 3 5 15 15 15 9 Calcium-binding EGF domain EGF_3 PF12947.7 RUS73491.1 - 2.8e-12 46.6 188.6 0.00015 21.9 3.8 16.5 13 3 2 15 15 15 10 EGF domain FXa_inhibition PF14670.6 RUS73491.1 - 2.2e-06 27.8 180.6 0.073 13.4 9.1 15.0 5 3 9 14 14 14 9 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 RUS73491.1 - 9.9e-05 22.6 239.7 0.07 13.5 7.3 15.7 15 0 0 15 15 15 10 EGF-like domain cEGF PF12662.7 RUS73491.1 - 0.00022 21.1 12.0 0.0029 17.5 1.2 15.9 16 1 0 16 16 16 8 Complement Clr-like EGF-like EGF PF00008.27 RUS73492.1 - 1e-21 76.8 56.6 1.9e-05 24.8 4.5 5.5 5 0 0 5 5 5 5 EGF-like domain EGF_CA PF07645.15 RUS73492.1 - 1.8e-14 53.6 65.2 1.1e-07 31.9 4.3 6.1 6 0 0 6 6 6 5 Calcium-binding EGF domain hEGF PF12661.7 RUS73492.1 - 7.3e-14 51.8 50.8 8.5e-05 23.0 2.6 6.5 5 0 0 5 5 5 5 Human growth factor-like EGF FXa_inhibition PF14670.6 RUS73492.1 - 1.8e-07 31.3 50.4 0.013 15.8 3.1 5.6 4 2 1 5 5 5 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 RUS73492.1 - 2.9e-07 30.6 55.9 0.00048 20.3 6.2 6.4 5 2 1 6 6 6 5 EGF domain cEGF PF12662.7 RUS73492.1 - 0.042 13.8 0.4 0.042 13.8 0.4 7.6 6 1 0 6 6 6 0 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 RUS73493.1 - 1.4e-14 54.7 0.0 1.7e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS73493.1 - 1.1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Laminin G domain Ribosomal_L32p PF01783.23 RUS73495.1 - 7.8e-06 26.1 0.6 1.3e-05 25.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 RUS73495.1 - 0.003 17.1 2.5 0.0038 16.8 1.5 1.6 2 0 0 2 2 2 1 RecR protein AIF_C PF14721.6 RUS73496.1 - 1.2e-52 177.8 0.6 7.3e-52 175.2 0.0 2.2 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 RUS73496.1 - 2.4e-43 148.4 0.0 3.4e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Deltameth_res PF16020.5 RUS73496.1 - 1.2e-15 57.1 0.1 2.4e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Deltamethrin resistance Pyr_redox PF00070.27 RUS73496.1 - 7e-13 48.9 0.2 1e-11 45.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS73496.1 - 3.1e-06 26.7 0.0 8.7e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS73496.1 - 0.00039 20.4 0.8 1.8 8.5 0.0 4.0 2 2 2 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 RUS73496.1 - 0.00066 19.4 1.6 0.11 12.0 0.0 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase IstB_IS21 PF01695.17 RUS73496.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein HI0933_like PF03486.14 RUS73496.1 - 0.15 10.8 0.2 5.7 5.5 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein VCBS PF13517.6 RUS73497.1 - 2e-10 41.1 9.5 0.00017 22.1 2.7 4.7 5 0 0 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RUS73497.1 - 8.1e-08 32.3 11.3 0.076 13.2 2.5 3.9 3 0 0 3 3 3 3 FG-GAP repeat PQQ_3 PF13570.6 RUS73497.1 - 0.0017 18.8 7.1 4.3 8.0 0.2 5.4 4 1 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 RUS73497.1 - 0.003 17.2 0.2 0.012 15.2 0.2 2.1 2 1 0 2 2 2 1 PQQ-like domain TcdB_toxin_midN PF12256.8 RUS73497.1 - 0.015 14.6 1.2 8.6 5.7 0.1 3.5 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region PQQ PF01011.21 RUS73497.1 - 0.032 14.2 6.1 5.7 7.0 0.1 4.6 6 0 0 6 6 6 0 PQQ enzyme repeat Fucokinase PF07959.12 RUS73498.1 - 2.7e-110 369.1 0.3 3.9e-110 368.6 0.3 1.2 1 0 0 1 1 1 1 L-fucokinase Nucleoporin_FG2 PF15967.5 RUS73499.1 - 2.8e-92 310.2 58.1 8.6e-92 308.6 58.1 1.9 1 1 0 1 1 1 1 Nucleoporin FG repeated region SKA1 PF07160.12 RUS73499.1 - 0.12 12.2 7.6 0.083 12.7 2.8 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Apolipoprotein PF01442.18 RUS73499.1 - 0.25 11.2 7.7 0.69 9.8 7.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain L31 PF09784.9 RUS73499.1 - 1 9.8 3.5 1.9 8.9 1.2 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DASH_Spc34 PF08657.10 RUS73499.1 - 1.3 8.7 4.4 2.4 7.9 4.4 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF1664 PF07889.12 RUS73499.1 - 1.5 8.9 7.1 29 4.7 0.2 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 RUS73499.1 - 3.6 7.7 7.7 3.6 7.7 6.3 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Spectrin PF00435.21 RUS73499.1 - 4.4 7.8 6.3 5.2 7.6 0.7 2.3 2 0 0 2 2 2 0 Spectrin repeat CENP-H PF05837.12 RUS73499.1 - 5.7 7.4 6.9 6.2 7.3 0.2 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PepX_N PF09168.10 RUS73500.1 - 9.2 6.7 9.0 0.81 10.1 2.0 2.8 2 1 1 3 3 3 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal NARG2_C PF10505.9 RUS73501.1 - 1.5e-38 132.5 0.0 4.3e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Poty_coat PF00767.18 RUS73501.1 - 0.069 12.7 0.4 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Potyvirus coat protein Lipocalin_3 PF12702.7 RUS73501.1 - 0.091 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Lipocalin-like PDZ PF00595.24 RUS73502.1 - 1.2e-12 48.0 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS73502.1 - 2.6e-06 27.2 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS73502.1 - 7.3e-05 23.0 0.0 9.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain DUF5334 PF17268.2 RUS73502.1 - 0.072 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5334) Apc13p PF05839.11 RUS73503.1 - 4.2e-12 46.1 2.8 7e-12 45.4 2.8 1.4 1 1 0 1 1 1 1 Apc13p protein NARP1 PF12569.8 RUS73504.1 - 5.4e-197 655.8 17.1 1.1e-196 654.7 17.1 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 RUS73504.1 - 1.1e-13 50.2 18.9 0.0017 18.4 0.1 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73504.1 - 4.9e-13 48.7 1.7 0.14 13.0 0.0 9.5 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS73504.1 - 1.3e-12 46.8 23.6 0.0011 18.9 0.1 9.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS73504.1 - 2e-12 47.4 15.0 3.1e-05 24.4 0.8 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS73504.1 - 3.5e-10 40.0 11.5 0.45 10.8 0.0 7.7 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73504.1 - 3.6e-09 36.1 22.5 0.0083 15.9 0.1 9.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS73504.1 - 1.1e-08 34.5 4.6 0.14 12.2 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS73504.1 - 7.9e-07 28.6 11.1 0.0033 16.7 0.4 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS73504.1 - 0.00012 21.7 2.6 0.00073 19.2 0.1 3.5 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 RUS73504.1 - 0.00046 20.4 11.4 0.23 11.9 0.0 7.9 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS73504.1 - 0.00055 20.5 4.2 17 6.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS73504.1 - 0.00088 19.5 18.3 0.0079 16.4 0.5 5.9 4 2 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RUS73504.1 - 0.0018 18.3 2.7 4.5 7.4 0.0 5.0 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 RUS73504.1 - 0.0025 17.9 2.5 0.35 11.0 0.2 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS73504.1 - 0.014 16.0 15.7 15 6.5 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 RUS73504.1 - 0.029 15.0 0.0 51 4.9 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat SLR1-BP PF07333.12 RUS73504.1 - 2.7 8.5 5.6 1.2 9.6 0.7 2.5 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) ATP-synt_E PF05680.12 RUS73504.1 - 5.4 7.4 7.6 18 5.7 7.6 1.9 1 0 0 1 1 1 0 ATP synthase E chain Fis1_TPR_C PF14853.6 RUS73504.1 - 9.5 6.4 10.3 31 4.7 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Trypsin_2 PF13365.6 RUS73506.1 - 1.6e-08 35.6 0.1 3.1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Fic PF02661.18 RUS73507.1 - 3.6e-27 95.1 0.0 1.5e-26 93.1 0.0 2.1 1 0 0 1 1 1 1 Fic/DOC family TPR_2 PF07719.17 RUS73507.1 - 0.00015 21.6 0.0 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73507.1 - 0.00076 19.2 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS73507.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 RUS73507.1 - 0.0017 19.0 0.0 0.054 14.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS73507.1 - 0.0058 16.5 0.5 0.055 13.4 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73507.1 - 0.0084 16.9 0.1 0.043 14.6 0.1 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS73507.1 - 0.012 15.9 0.1 2.5 8.7 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS73507.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS73507.1 - 0.083 13.2 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS73507.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4172 PF13776.6 RUS73507.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Nup35_RRM PF05172.13 RUS73508.1 - 6.8e-21 74.1 0.1 1.4e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 RUS73508.1 - 4.3e-10 39.4 0.1 6.8e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PspB PF06667.12 RUS73508.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B Forkhead PF00250.18 RUS73509.1 - 5.3e-33 113.1 0.0 9.3e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain VWA PF00092.28 RUS73510.1 - 9.4e-05 22.7 0.4 0.00011 22.5 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS73510.1 - 0.00046 20.8 0.1 0.00057 20.5 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 RUS73511.1 - 0.023 14.9 0.2 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain CBM_14 PF01607.24 RUS73513.1 - 1.8e-07 31.2 3.7 1.8e-07 31.2 3.7 2.8 3 1 0 3 3 3 1 Chitin binding Peritrophin-A domain DNA_mis_repair PF01119.19 RUS73513.1 - 0.16 11.7 0.4 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain VWA_2 PF13519.6 RUS73514.1 - 1.9e-10 41.3 0.1 0.0058 17.3 0.0 3.7 2 2 1 4 4 4 2 von Willebrand factor type A domain VWA PF00092.28 RUS73514.1 - 4.4e-08 33.6 0.0 0.0014 19.0 0.0 2.6 3 1 0 3 3 3 2 von Willebrand factor type A domain T2SSL PF05134.13 RUS73514.1 - 0.017 14.5 0.1 5.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein L KRBA1 PF15287.6 RUS73514.1 - 0.048 13.4 0.6 0.31 10.8 0.1 2.7 2 0 0 2 2 2 0 KRBA1 family repeat Sulfate_transp PF00916.20 RUS73515.1 - 6.6e-98 327.9 16.6 1e-97 327.3 16.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RUS73515.1 - 1.2e-25 89.4 0.0 3.1e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RUS73515.1 - 0.0062 16.9 2.1 0.0062 16.9 2.1 2.7 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily DDE_Tnp_4 PF13359.6 RUS73517.1 - 4.2e-24 85.0 0.0 7.8e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YqaJ PF09588.10 RUS73517.1 - 6.4e-11 42.6 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Viral_alk_exo PF01771.17 RUS73517.1 - 5.6e-06 25.5 0.0 8.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Viral alkaline exonuclease DDE_Tnp_1 PF01609.21 RUS73517.1 - 0.00011 21.9 0.0 0.0055 16.4 0.0 2.3 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 RUS73517.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Plant transposon protein SPEG_u2 PF16650.5 RUS73517.1 - 0.096 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Methyltransf_5 PF01795.19 RUS73518.1 - 1.4e-25 90.5 0.3 3.1e-25 89.3 0.3 1.5 1 1 0 1 1 1 1 MraW methylase family KIAA1430 PF13879.6 RUS73519.1 - 5e-25 88.2 5.0 5e-25 88.2 5.0 4.0 1 1 1 2 2 2 1 KIAA1430 homologue Mitofilin PF09731.9 RUS73519.1 - 5.4 5.7 52.6 6.5 5.5 52.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.7 RUS73519.1 - 6.4 4.8 33.4 7.9 4.5 33.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_2 PF07727.14 RUS73520.1 - 1.4e-32 113.3 0.0 3.1e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS73520.1 - 4.7e-20 71.9 0.0 1.3e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 RUS73520.1 - 6.7e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 RUS73520.1 - 1e-06 28.5 0.2 1e-06 28.5 0.2 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 RUS73520.1 - 0.0026 17.5 0.0 0.0092 15.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_4 PF14392.6 RUS73520.1 - 9.1 6.1 9.7 3.7 7.3 1.4 2.7 2 0 0 2 2 2 0 Zinc knuckle Complex1_51K PF01512.17 RUS73521.1 - 4.5e-50 169.5 0.0 7.4e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 RUS73521.1 - 4.1e-30 103.7 0.2 4.1e-30 103.7 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 RUS73521.1 - 5.8e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 RUS73521.1 - 0.088 12.9 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Phytochelatin_C PF09328.10 RUS73522.1 - 0.61 9.4 3.7 1.4 8.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1984) Band_7 PF01145.25 RUS73524.1 - 2.4e-26 92.8 3.4 3.5e-26 92.3 3.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 RUS73524.1 - 0.004 17.3 0.9 0.0064 16.6 0.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 Peptidase_S66 PF02016.15 RUS73524.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain E_Pc_C PF06752.12 RUS73524.1 - 0.11 12.6 2.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus MgtE_N PF03448.17 RUS73524.1 - 0.12 13.0 2.7 11 6.7 0.6 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain DDE_Tnp_IS1595 PF12762.7 RUS73525.1 - 1.8e-20 73.5 0.0 3.9e-20 72.4 0.0 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain DUF5075 PF16825.5 RUS73525.1 - 0.011 15.5 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 IGP family C-type lectin domain LRR_6 PF13516.6 RUS73526.1 - 2.5e-05 24.0 2.5 0.62 10.3 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 RUS73526.1 - 0.0002 21.7 0.0 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS73526.1 - 0.0066 16.8 1.3 2.8 8.8 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat Pkinase PF00069.25 RUS73527.1 - 3.8e-58 196.9 0.0 5.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73527.1 - 1e-23 84.0 0.1 1.7e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS73527.1 - 4.3e-06 26.8 0.4 0.00032 20.7 0.0 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RUS73527.1 - 0.0099 15.5 3.5 0.016 14.8 3.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Chloroplast_duf PF14476.6 RUS73527.1 - 0.016 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Petal formation-expressed Kdo PF06293.14 RUS73527.1 - 0.051 12.9 0.9 0.081 12.3 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 RUS73527.1 - 0.1 12.1 6.2 3.1 7.3 6.2 2.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL LEM PF03020.15 RUS73528.1 - 5.7e-11 41.8 0.0 8.3e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 LEM domain hNIFK_binding PF12196.8 RUS73528.1 - 0.06 12.8 0.8 0.11 12.1 0.8 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK MAP17 PF15807.5 RUS73528.1 - 0.53 10.5 1.5 0.59 10.4 0.2 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ECH_1 PF00378.20 RUS73529.1 - 1.1e-57 195.2 0.0 1.4e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS73529.1 - 1.6e-25 90.3 0.0 2.5e-22 79.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RVT_1 PF00078.27 RUS73530.1 - 5.5e-17 62.0 0.0 8.4e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 RUS73530.1 - 0.046 13.6 5.6 0.085 12.8 5.6 1.4 1 0 0 1 1 1 0 PHD-finger DUF4093 PF13331.6 RUS73530.1 - 0.077 13.4 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4093) PHD_2 PF13831.6 RUS73530.1 - 0.26 10.9 7.3 0.52 9.9 7.3 1.5 1 0 0 1 1 1 0 PHD-finger RVT_1 PF00078.27 RUS73531.1 - 3.4e-18 66.0 0.0 5.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 RUS73531.1 - 0.06 12.9 6.0 0.13 11.9 6.0 1.5 1 0 0 1 1 1 0 PHD-finger PHD PF00628.29 RUS73531.1 - 0.1 12.5 5.2 0.2 11.6 5.2 1.4 1 0 0 1 1 1 0 PHD-finger Fe_bilin_red PF05996.12 RUS73532.1 - 0.14 11.8 1.9 0.42 10.3 0.9 1.8 1 1 1 2 2 2 0 Ferredoxin-dependent bilin reductase CbtB PF09489.10 RUS73532.1 - 0.74 10.0 2.9 25 5.1 0.1 2.5 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF1242 PF06842.12 RUS73533.1 - 3.3e-12 46.0 1.4 4.9e-12 45.4 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 RUS73533.1 - 0.013 15.8 1.8 0.013 15.7 1.6 1.3 1 1 0 1 1 1 0 LST-1 protein Spo7 PF03907.13 RUS73533.1 - 0.043 13.3 0.3 0.043 13.3 0.3 1.0 1 0 0 1 1 1 0 Spo7-like protein TMIE PF16038.5 RUS73533.1 - 0.3 10.9 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 TMIE protein CD225 PF04505.12 RUS73534.1 - 1e-08 35.2 0.2 2e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Chordopox_L2 PF05803.12 RUS73534.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus L2 protein RINGv PF12906.7 RUS73535.1 - 2e-14 53.5 11.2 3.1e-14 52.8 11.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 RUS73535.1 - 0.0031 17.8 6.7 0.0064 16.8 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain DUF2517 PF10725.9 RUS73535.1 - 0.0064 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) FANCL_C PF11793.8 RUS73535.1 - 0.0089 16.2 6.4 0.0089 16.2 6.4 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zinc_ribbon_4 PF13717.6 RUS73535.1 - 0.02 14.8 0.2 0.045 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-CSL PF05207.13 RUS73535.1 - 0.067 12.9 2.1 0.12 12.1 2.1 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF983 PF06170.12 RUS73535.1 - 0.24 11.8 4.9 0.16 12.4 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) zf-RING_4 PF14570.6 RUS73535.1 - 0.29 11.0 5.9 0.69 9.8 5.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 RUS73535.1 - 0.66 9.9 8.7 1.3 8.9 8.6 1.6 1 1 0 1 1 1 0 PHD-finger VirB3 PF05101.13 RUS73535.1 - 2.5 8.4 5.2 2.2 8.5 1.7 2.4 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Glycos_transf_2 PF00535.26 RUS73536.1 - 1.1e-29 103.4 0.0 1.8e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS73536.1 - 7.7e-13 48.8 0.9 1.4e-12 47.9 0.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 RUS73536.1 - 7.9e-06 25.5 0.0 1.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS73536.1 - 8e-05 22.2 0.2 0.0002 20.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase AvrM_N PF18247.1 RUS73536.1 - 0.041 13.8 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain NDUF_B7 PF05676.13 RUS73536.1 - 0.15 11.8 0.5 1.9 8.3 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) AD PF09793.9 RUS73537.1 - 1e-23 83.2 0.2 1.7e-23 82.6 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain 7tm_1 PF00001.21 RUS73538.1 - 1.3e-14 54.1 5.9 1.9e-14 53.7 5.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73538.1 - 7.2e-10 38.9 8.1 7.2e-10 38.9 8.1 2.3 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS73538.1 - 4.5e-07 29.5 12.0 4.1e-06 26.3 12.0 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw SKI PF01202.22 RUS73539.1 - 2.5e-10 40.7 0.0 1.2e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 RUS73539.1 - 8.3e-08 32.8 0.0 1.4e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS73539.1 - 5e-07 30.0 0.0 1.4e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RUS73539.1 - 1.2e-05 25.8 0.3 0.00017 22.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 RUS73539.1 - 0.00025 20.6 0.1 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 RUS73539.1 - 0.00036 20.5 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase dNK PF01712.19 RUS73539.1 - 0.00053 19.9 0.1 0.025 14.5 0.1 2.2 1 1 0 1 1 1 1 Deoxynucleoside kinase SRP54 PF00448.22 RUS73539.1 - 0.00058 19.5 0.3 0.0012 18.5 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CPT PF07931.12 RUS73539.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.17 RUS73539.1 - 0.0023 17.7 0.3 0.12 12.1 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin2 PF13189.6 RUS73539.1 - 0.0027 17.8 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.6 RUS73539.1 - 0.0034 17.8 0.0 0.005 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RUS73539.1 - 0.0044 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2373 PF10180.9 RUS73539.1 - 0.0053 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) AAA PF00004.29 RUS73539.1 - 0.0074 16.7 0.1 0.011 16.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 RUS73539.1 - 0.0094 15.7 0.1 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase CoaE PF01121.20 RUS73539.1 - 0.012 15.3 0.2 0.055 13.1 0.0 2.0 2 1 0 2 2 2 0 Dephospho-CoA kinase RNA_helicase PF00910.22 RUS73539.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 RUS73539.1 - 0.013 15.7 0.1 0.018 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RUS73539.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 RUS73539.1 - 0.02 14.5 1.1 0.21 11.1 1.1 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RUS73539.1 - 0.027 14.5 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 RUS73539.1 - 0.054 13.5 0.1 0.15 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS73539.1 - 0.057 13.1 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RUS73539.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 RUS73539.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 RUS73539.1 - 0.076 12.2 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 RUS73539.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RUS73539.1 - 0.089 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 RUS73539.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RUS73539.1 - 0.094 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 RUS73539.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 RUS73539.1 - 0.12 11.8 0.1 2.6 7.5 0.1 2.2 1 1 1 2 2 2 0 PhoH-like protein RuvB_N PF05496.12 RUS73539.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TPR_12 PF13424.6 RUS73540.1 - 1.4e-33 115.0 32.3 4.9e-11 42.8 0.2 9.2 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73540.1 - 7.4e-24 82.5 37.5 1.3e-05 24.8 0.0 13.2 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.17 RUS73540.1 - 1.4e-22 77.9 37.3 1.8e-05 24.5 0.1 13.2 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_7 PF13176.6 RUS73540.1 - 1.7e-13 49.5 24.1 0.0085 16.1 0.0 11.1 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 RUS73540.1 - 9.6e-12 44.4 26.1 0.021 14.7 0.0 11.4 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS73540.1 - 2.7e-10 39.6 41.4 0.19 12.0 0.0 13.3 14 1 0 14 14 14 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS73540.1 - 4.6e-10 40.0 12.9 0.002 18.7 0.0 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73540.1 - 3.4e-07 30.5 19.1 5.7 8.0 0.0 11.4 14 0 0 14 14 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS73540.1 - 4.9e-07 29.3 15.7 0.077 12.7 0.0 7.2 8 0 0 8 8 8 3 TPR repeat TPR_MalT PF17874.1 RUS73540.1 - 8.6e-07 28.6 22.3 0.008 15.6 0.3 6.0 5 1 1 6 6 6 3 MalT-like TPR region ANAPC3 PF12895.7 RUS73540.1 - 9e-06 25.8 20.7 0.18 12.1 0.4 7.8 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 RUS73540.1 - 2.7e-05 24.1 15.4 1.3 9.1 0.0 7.2 7 0 0 7 7 6 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 RUS73540.1 - 0.00024 21.5 23.0 13 6.7 0.1 10.4 12 0 0 12 12 12 0 Tetratricopeptide repeat RPN7 PF10602.9 RUS73540.1 - 0.034 13.9 0.1 0.034 13.9 0.1 4.8 6 0 0 6 6 6 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 RUS73540.1 - 1.2 8.8 20.3 1.8 8.2 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat-like domain RINGv PF12906.7 RUS73541.1 - 2.9e-14 52.9 6.5 5.1e-14 52.1 6.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 RUS73541.1 - 0.0077 16.5 5.4 0.014 15.7 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain DUF3318 PF11780.8 RUS73541.1 - 0.085 12.8 0.2 9.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Zn_ribbon_17 PF17120.5 RUS73541.1 - 0.33 10.6 3.0 0.78 9.4 3.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HemY_N PF07219.13 RUS73541.1 - 2.2 8.5 6.8 0.3 11.3 2.5 1.7 2 0 0 2 2 2 0 HemY protein N-terminus Spaetzle PF16077.5 RUS73542.1 - 0.0017 18.9 0.0 0.0035 17.8 0.0 1.6 1 1 0 1 1 1 1 Spaetzle BTB PF00651.31 RUS73543.1 - 1.1e-14 54.6 0.0 2.4e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS73543.1 - 4.3e-09 36.4 0.4 1.4e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch zf-C2H2 PF00096.26 RUS73546.1 - 5.5e-38 127.3 93.1 3.7e-05 23.9 0.6 13.3 13 1 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS73546.1 - 8.7e-36 119.5 87.8 5.5e-05 23.7 1.0 13.0 13 0 0 13 13 13 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS73546.1 - 1.2e-27 95.1 94.0 3.3e-06 27.3 0.6 14.1 12 2 2 14 14 14 11 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS73546.1 - 8.1e-24 83.3 55.4 0.002 18.4 0.0 12.4 13 0 0 13 13 13 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS73546.1 - 2.7e-19 68.9 66.3 0.00027 21.2 0.3 12.6 13 1 0 13 13 13 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS73546.1 - 1e-16 60.5 76.0 0.00041 20.3 0.9 13.0 13 0 0 13 13 13 7 C2H2-type zinc finger GAGA PF09237.11 RUS73546.1 - 0.00097 18.9 0.3 0.00097 18.9 0.3 6.1 4 2 5 9 9 9 1 GAGA factor Zn-ribbon_8 PF09723.10 RUS73546.1 - 0.0045 17.1 54.7 0.096 12.8 1.0 9.8 7 4 3 10 10 10 3 Zinc ribbon domain zf_UBZ PF18439.1 RUS73546.1 - 0.011 15.3 45.4 0.64 9.7 0.0 11.8 13 0 0 13 13 13 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 RUS73546.1 - 0.016 15.2 3.0 0.016 15.2 3.0 6.7 1 1 4 6 6 6 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_IE-1 PF05290.11 RUS73546.1 - 0.02 14.8 5.2 0.02 14.8 5.2 5.2 4 3 1 5 5 5 0 Baculovirus immediate-early protein (IE-0) zf_ZIC PF18366.1 RUS73546.1 - 0.036 14.2 1.4 0.036 14.2 1.4 8.6 7 3 2 9 9 9 0 Zic proteins zinc finger domain zf-C2H2_9 PF16293.5 RUS73546.1 - 0.14 12.0 26.8 6 6.8 0.1 7.9 7 2 2 9 9 9 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 RUS73546.1 - 0.2 12.2 0.1 0.2 12.2 0.1 10.3 11 1 0 11 11 9 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 RUS73546.1 - 0.33 11.7 43.1 0.4 11.5 1.5 6.8 1 1 5 7 7 7 0 zinc-ribbon family Ta0938 PF11494.8 RUS73546.1 - 0.43 10.9 0.1 0.43 10.9 0.1 6.9 1 1 8 9 9 9 0 Ta0938 zf-C2H2_3rep PF18868.1 RUS73546.1 - 0.53 11.0 43.1 3 8.5 0.3 8.0 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 RUS73546.1 - 7.8 6.9 58.1 0.87 10.0 4.9 9.3 1 1 8 10 10 10 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RUS73546.1 - 9 6.5 73.3 0.42 10.8 5.1 7.6 2 1 4 6 6 6 0 FYVE zinc finger DUF1199 PF06712.11 RUS73547.1 - 0.063 13.3 0.1 0.23 11.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Ribosomal_L11_N PF03946.14 RUS73548.1 - 1e-25 89.3 0.3 1.8e-25 88.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RUS73548.1 - 1.9e-25 89.1 0.1 3.3e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RPAP1_C PF08620.10 RUS73549.1 - 3e-24 84.9 0.1 2.6e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 RUS73549.1 - 8.4e-15 54.3 3.6 8.4e-15 54.3 3.6 2.1 2 0 0 2 2 2 1 RPAP1-like, N-terminal CLASP_N PF12348.8 RUS73550.1 - 4.6e-29 101.6 13.0 2.8e-13 50.0 0.0 4.7 5 0 0 5 5 5 3 CLASP N terminal Cnd1 PF12717.7 RUS73550.1 - 3e-12 46.9 18.3 0.002 18.2 3.7 7.0 5 2 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RUS73550.1 - 1.1e-10 41.7 0.5 0.004 17.5 0.0 6.9 4 2 3 8 8 8 3 HEAT repeats HEAT PF02985.22 RUS73550.1 - 3.8e-10 39.1 3.1 0.61 10.5 0.0 8.0 9 0 0 9 9 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 RUS73550.1 - 1.3e-06 28.9 2.4 4.8 7.9 0.0 5.6 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 RUS73550.1 - 0.00018 21.7 5.3 0.34 11.1 0.0 5.7 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 RUS73550.1 - 0.00094 19.1 6.3 0.083 12.8 1.1 3.5 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Dopey_N PF04118.14 RUS73550.1 - 0.0012 18.0 8.3 2.6 7.1 0.2 4.0 5 0 0 5 5 5 3 Dopey, N-terminal HEAT_EZ PF13513.6 RUS73550.1 - 0.0027 18.1 1.4 6.4 7.4 0.0 5.2 5 1 0 5 5 5 1 HEAT-like repeat Pinin_SDK_memA PF04696.13 RUS73550.1 - 0.029 14.4 24.1 0.078 13.0 22.9 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3915 PF13054.6 RUS73550.1 - 0.086 12.8 2.8 0.27 11.2 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF5071 PF16804.5 RUS73550.1 - 0.12 12.7 0.8 10 6.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) NUC173 PF08161.12 RUS73550.1 - 0.14 11.8 3.4 2.7 7.6 0.5 3.5 3 1 0 3 3 3 0 NUC173 domain UME PF08064.13 RUS73550.1 - 0.3 11.0 5.8 2.2 8.3 0.1 4.6 3 2 1 4 4 4 0 UME (NUC010) domain CAF-1_p150 PF11600.8 RUS73550.1 - 1.6 8.4 29.4 3.5 7.3 29.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EF-hand_1 PF00036.32 RUS73551.1 - 6.2e-39 128.7 15.5 5.8e-09 34.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS73551.1 - 9.5e-36 122.1 4.9 1.2e-17 64.1 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS73551.1 - 2.5e-30 101.8 9.5 6.3e-10 38.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RUS73551.1 - 1.9e-29 101.3 12.4 1.2e-12 47.5 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RUS73551.1 - 2.8e-28 96.1 10.6 5.3e-07 28.8 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS73551.1 - 6.5e-15 55.2 0.2 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS73551.1 - 1.9e-09 37.8 0.1 0.00019 21.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS73551.1 - 2.9e-09 36.8 0.5 0.00015 21.7 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RUS73551.1 - 3e-07 30.5 4.2 0.00021 21.4 0.6 3.1 2 2 1 3 3 3 3 Dockerin type I domain UPF0154 PF03672.13 RUS73551.1 - 1.4e-05 25.0 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RUS73551.1 - 5.4e-05 24.0 0.1 0.0067 17.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 RUS73551.1 - 6.9e-05 22.6 1.3 8.9e-05 22.2 1.3 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 RUS73551.1 - 0.001 19.0 1.9 2.4 8.1 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 RUS73551.1 - 0.0037 17.6 0.4 1.9 8.9 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 RUS73551.1 - 0.0073 14.9 0.0 0.0081 14.7 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DIT1_PvcA PF05141.12 RUS73551.1 - 0.015 14.8 0.4 0.019 14.4 0.4 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF3349 PF11829.8 RUS73551.1 - 0.017 15.9 0.2 12 6.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) SurA_N_2 PF13623.6 RUS73551.1 - 0.018 14.9 0.7 0.074 12.9 0.3 2.1 1 1 1 2 2 2 0 SurA N-terminal domain TerB PF05099.13 RUS73551.1 - 0.024 14.6 0.3 3.6 7.5 0.0 2.5 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF1296 PF06972.11 RUS73551.1 - 0.025 14.7 1.3 0.75 10.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) RNA_pol_Rpb4 PF03874.16 RUS73551.1 - 0.028 14.8 0.7 1.3 9.3 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb4 SurA_N_3 PF13624.6 RUS73551.1 - 0.034 13.9 0.4 0.38 10.5 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Phage_TAC_12 PF12363.8 RUS73551.1 - 0.035 14.5 0.3 3.3 8.1 0.0 2.7 2 1 1 3 3 3 0 Phage tail assembly chaperone protein, TAC MotA_activ PF09114.10 RUS73551.1 - 0.067 13.3 0.2 0.26 11.4 0.1 2.0 1 1 2 3 3 3 0 Transcription factor MotA, activation domain FGAR-AT_linker PF18072.1 RUS73551.1 - 0.089 13.3 0.0 2 9.0 0.0 2.6 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Mu-like_Pro PF10123.9 RUS73551.1 - 0.095 12.2 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Toprim PF01751.22 RUS73551.1 - 0.13 12.5 0.3 0.5 10.6 0.0 2.0 1 1 1 2 2 2 0 Toprim domain Ssl1 PF04056.14 RUS73552.1 - 5.5e-81 271.0 0.0 1.1e-80 270.0 0.0 1.4 2 0 0 2 2 2 1 Ssl1-like C1_4 PF07975.12 RUS73552.1 - 3.6e-15 56.0 20.8 1.7e-13 50.6 11.4 2.9 1 1 1 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 RUS73552.1 - 1.6e-11 44.8 0.0 2.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RUS73552.1 - 5.9e-06 26.6 0.0 7.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain MukF_M PF17192.4 RUS73552.1 - 0.0058 16.4 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 MukF middle domain VWA_3 PF13768.6 RUS73552.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_4 PF14570.6 RUS73552.1 - 0.014 15.2 11.1 0.093 12.5 4.2 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4428 PF14471.6 RUS73552.1 - 0.17 11.8 9.3 1.3 9.0 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-AN1 PF01428.16 RUS73552.1 - 0.44 10.7 21.5 0.14 12.4 5.2 3.6 2 1 1 3 3 3 0 AN1-like Zinc finger Zn_ribbon_SprT PF17283.2 RUS73552.1 - 0.55 10.2 5.6 8.9 6.3 0.1 3.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 RUS73552.1 - 2.5 8.1 14.5 77 3.4 9.3 4.1 3 1 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.7 RUS73552.1 - 5.2 7.2 13.1 50 4.0 13.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 RUS73552.1 - 9 6.6 20.7 0.58 10.4 7.4 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain dNK PF01712.19 RUS73553.1 - 1.4e-56 191.6 0.1 1.7e-56 191.3 0.1 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 RUS73553.1 - 1e-07 32.5 0.3 6.7e-07 29.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS73553.1 - 9.9e-07 29.0 0.0 5.3e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RUS73553.1 - 6.3e-05 23.4 0.1 0.00024 21.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 RUS73553.1 - 0.0036 16.5 0.0 0.0048 16.1 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Thymidylate_kin PF02223.17 RUS73553.1 - 0.0039 16.9 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase NFRKB_winged PF14465.6 RUS73553.1 - 0.009 16.2 0.4 0.59 10.4 0.4 2.3 1 1 0 1 1 1 1 NFRKB Winged Helix-like CoaE PF01121.20 RUS73553.1 - 0.015 15.0 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Ploopntkinase1 PF18748.1 RUS73553.1 - 0.02 14.4 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_16 PF13191.6 RUS73553.1 - 0.023 15.1 0.0 0.031 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 RUS73553.1 - 0.031 13.5 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 RUS73553.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ins_P5_2-kin PF06090.12 RUS73553.1 - 0.054 12.9 0.1 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase NACHT PF05729.12 RUS73553.1 - 0.074 13.0 0.2 0.54 10.2 0.0 2.1 2 1 0 2 2 2 0 NACHT domain TsaE PF02367.17 RUS73553.1 - 0.087 12.8 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bclt PF15318.6 RUS73554.1 - 5.3 6.8 6.1 1.5 8.6 2.2 1.9 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis zf-C3HC4 PF00097.25 RUS73556.1 - 7.1e-07 29.0 6.1 1e-06 28.5 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS73556.1 - 0.00041 20.5 9.4 0.00061 19.9 9.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS73556.1 - 0.00042 20.1 7.2 0.00079 19.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS73556.1 - 0.0005 20.0 2.9 0.0005 20.0 2.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS73556.1 - 0.00057 20.2 8.0 0.001 19.4 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS73556.1 - 0.00076 19.3 5.1 0.0011 18.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS73556.1 - 0.0011 18.9 4.8 0.0019 18.2 4.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 RUS73556.1 - 0.0084 16.2 4.0 0.012 15.8 4.0 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 RUS73556.1 - 0.016 15.1 2.4 0.023 14.6 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 RUS73556.1 - 0.018 14.9 6.6 0.041 13.7 6.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 RUS73556.1 - 0.086 12.7 5.6 2.5 8.0 2.5 2.2 2 0 0 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 RUS73556.1 - 0.4 11.0 7.0 1.4 9.3 7.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain TMEM43 PF07787.12 RUS73557.1 - 1 8.7 4.0 1.5 8.1 4.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 P5-ATPase PF12409.8 RUS73558.1 - 5e-23 81.6 0.9 3.7e-22 78.7 0.9 2.0 1 1 0 1 1 1 1 P5-type ATPase cation transporter CaKB PF03185.15 RUS73558.1 - 0.15 11.7 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Ysc84 PF04366.12 RUS73559.1 - 1.2e-40 138.2 0.0 1.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator 7tm_1 PF00001.21 RUS73561.1 - 6.8e-23 81.3 3.0 1.2e-15 57.5 0.7 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73561.1 - 1.6e-06 28.0 7.9 3.8e-05 23.5 4.3 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Fez1 PF06818.15 RUS73563.1 - 0.00064 20.2 45.9 0.005 17.3 0.8 4.0 1 1 3 4 4 4 2 Fez1 Filament PF00038.21 RUS73563.1 - 0.0084 15.7 47.4 0.068 12.7 14.3 3.9 3 1 1 4 4 4 2 Intermediate filament protein DUF641 PF04859.12 RUS73563.1 - 1.1 9.6 42.8 1 9.7 9.6 4.7 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) TACC_C PF05010.14 RUS73563.1 - 1.4 8.6 45.3 0.12 12.1 31.2 3.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 RUS73563.1 - 1.5 8.1 58.7 0.18 11.1 17.6 4.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 RUS73563.1 - 2.2 7.1 50.5 7.9 5.3 21.2 3.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 RUS73563.1 - 2.6 7.4 56.3 0.016 14.7 13.1 3.6 2 1 3 5 5 5 0 Golgin subfamily A member 5 CALCOCO1 PF07888.11 RUS73563.1 - 3 6.6 56.4 0.17 10.7 32.7 2.6 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.7 RUS73563.1 - 3.1 8.0 59.5 4.7 7.4 5.3 5.4 1 1 4 5 5 5 0 Tropomyosin like LXG PF04740.12 RUS73563.1 - 5.2 6.7 34.5 0.074 12.7 4.7 3.7 1 1 2 3 3 3 0 LXG domain of WXG superfamily ERM PF00769.19 RUS73563.1 - 9.8 5.9 56.8 0.63 9.8 31.4 2.7 2 1 1 3 3 3 0 Ezrin/radixin/moesin family TatD_DNase PF01026.21 RUS73564.1 - 4.1e-07 29.6 0.0 5.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidase PF01425.21 RUS73565.1 - 2e-122 409.4 0.0 2.7e-122 409.0 0.0 1.2 1 0 0 1 1 1 1 Amidase CwfJ_C_1 PF04677.15 RUS73566.1 - 4.7e-35 120.1 0.3 7.9e-35 119.4 0.3 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RUS73566.1 - 5.9e-30 104.1 0.2 3.2e-29 101.7 0.2 2.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF5633 PF18656.1 RUS73566.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Ion_trans_N PF08412.10 RUS73566.1 - 0.66 9.6 3.1 1.3 8.7 0.2 3.2 2 0 0 2 2 2 0 Ion transport protein N-terminal IRK_N PF08466.10 RUS73567.1 - 0.00033 20.7 17.9 1.1e+02 3.1 0.0 8.4 9 0 0 9 9 9 0 Inward rectifier potassium channel N-terminal Pox_RNA_pol_35 PF03396.15 RUS73567.1 - 0.00033 20.0 0.1 5.6 6.1 0.0 3.5 1 1 3 4 4 4 4 Poxvirus DNA-directed RNA polymerase, 35 kD subunit EnY2 PF10163.9 RUS73567.1 - 0.00071 19.9 6.9 16 6.0 0.2 5.0 1 1 4 5 5 5 4 Transcription factor e(y)2 DUF4019 PF13211.6 RUS73567.1 - 0.097 13.1 8.2 59 4.1 0.1 3.9 1 1 3 5 5 5 0 Protein of unknown function (DUF4019) DUF3134 PF11332.8 RUS73568.1 - 0.0069 16.7 7.6 0.73 10.2 0.2 3.3 2 1 2 4 4 4 2 Protein of unknown function (DUF3134) PEX-2N PF09263.10 RUS73568.1 - 0.22 11.9 10.3 11 6.4 0.6 3.8 1 1 4 5 5 5 0 Peroxisome biogenesis factor 1, N-terminal C_Hendra PF16821.5 RUS73568.1 - 0.24 11.3 6.5 1.1 9.1 1.9 2.5 1 1 2 3 3 3 0 C protein from hendra and measles viruses TcpQ PF10671.9 RUS73568.1 - 0.71 10.0 11.0 0.64 10.2 0.7 2.9 2 1 1 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q Gp_dh_N PF00044.24 RUS73569.1 - 8.6e-38 128.7 0.0 1.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS73569.1 - 0.00089 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNase_H PF00075.24 RUS73570.1 - 4.6e-13 49.6 1.1 2.7e-12 47.1 1.1 2.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS73570.1 - 0.0049 16.7 0.1 0.0091 15.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like HATPase_c_5 PF14501.6 RUS73570.1 - 0.031 14.2 3.9 0.11 12.4 3.9 1.8 1 1 0 1 1 1 0 GHKL domain DUF445 PF04286.12 RUS73571.1 - 0.00013 21.9 1.6 0.00029 20.8 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF1997 PF09366.10 RUS73571.1 - 0.0006 20.0 28.5 3.4 7.8 1.4 8.2 1 1 4 5 5 5 2 Protein of unknown function (DUF1997) SAC3 PF12209.8 RUS73571.1 - 0.024 14.8 23.0 4.7 7.5 0.4 6.5 2 2 4 6 6 6 0 Leucine permease transcriptional regulator helical domain TetR_C_8 PF14278.6 RUS73571.1 - 0.12 12.5 9.9 16 5.6 0.1 5.8 1 1 3 5 5 5 0 Transcriptional regulator C-terminal region UcrQ PF02939.16 RUS73571.1 - 0.31 11.0 10.2 17 5.4 0.1 5.2 1 1 3 5 5 5 0 UcrQ family DUF5455 PF17537.2 RUS73571.1 - 0.83 10.1 16.6 1.3 9.4 1.3 5.1 1 1 3 5 5 5 0 Family of unknown function (DUF5455) Baculo_p74 PF04583.12 RUS73571.1 - 2.2 7.7 13.9 14 5.1 0.3 3.9 1 1 2 4 4 4 0 Baculoviridae p74 conserved region GlutR_dimer PF00745.20 RUS73571.1 - 8 7.0 22.3 3.7 8.1 0.7 6.3 2 1 2 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ribosomal_L5_C PF00673.21 RUS73572.1 - 0.0075 16.4 1.1 22 5.3 0.0 3.6 1 1 3 4 4 4 2 ribosomal L5P family C-terminus ILEI PF15711.5 RUS73572.1 - 0.066 13.7 4.0 4.8 7.7 0.1 3.0 1 1 2 3 3 3 0 Interleukin-like EMT inducer CytadhesinP1 PF12378.8 RUS73572.1 - 1.5 9.0 9.7 3.7e+02 1.4 0.0 6.8 9 0 0 9 9 9 0 Trypsin-sensitive surface-exposed protein Colicin_D PF11429.8 RUS73573.1 - 3.2e-06 27.5 53.8 7.5 7.1 0.0 16.3 17 0 0 17 17 17 2 Colicin D THEG PF14912.6 RUS73573.1 - 0.0019 18.6 73.7 5.1 7.6 2.0 14.9 2 2 14 16 16 16 4 Testicular haploid expressed repeat Alpha_adaptinC2 PF02883.20 RUS73573.1 - 0.12 12.7 0.4 0.5 10.7 0.4 2.1 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF1206 PF06724.11 RUS73573.1 - 0.24 11.5 1.9 11 6.2 0.0 5.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) ETC_C1_NDUFA5 PF04716.14 RUS73573.1 - 1.6 8.6 78.7 47 3.9 0.2 17.0 18 0 0 18 18 18 0 ETC complex I subunit conserved region DMAP_binding PF06464.11 RUS73573.1 - 2.7 8.8 59.3 15 6.4 1.6 9.8 1 1 13 15 15 15 0 DMAP1-binding Domain CreA PF05981.12 RUS73577.1 - 1.1e-05 25.4 9.1 0.58 10.1 0.6 4.9 1 1 4 5 5 5 4 CreA protein DUF190 PF02641.15 RUS73577.1 - 2.2e-05 24.7 15.1 5 7.5 0.3 7.8 1 1 6 8 8 8 2 Uncharacterized ACR, COG1993 RNase_Zc3h12a PF11977.8 RUS73577.1 - 0.0001 22.1 4.7 6.8 6.5 0.1 4.9 1 1 3 4 4 4 2 Zc3h12a-like Ribonuclease NYN domain IL17R_D_N PF16742.5 RUS73577.1 - 0.0019 18.3 6.1 7.8 6.6 0.0 4.6 1 1 4 5 5 5 1 N-terminus of interleukin 17 receptor D ExbD PF02472.16 RUS73577.1 - 0.013 15.6 15.0 4.8 7.4 3.5 4.5 1 1 2 3 3 3 0 Biopolymer transport protein ExbD/TolR Phage-A118_gp45 PF10653.9 RUS73577.1 - 0.018 15.0 12.5 12 6.0 0.1 6.5 2 2 2 7 7 7 0 Protein gp45 of Bacteriophage A118 ZFYVE21_C PF16696.5 RUS73577.1 - 0.034 14.0 4.8 2.8 7.8 0.4 4.2 1 1 2 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus ig PF00047.25 RUS73577.1 - 0.26 11.5 3.0 53 4.1 0.1 4.5 2 1 2 4 4 4 0 Immunoglobulin domain Pox_A6 PF04924.12 RUS73577.1 - 6.8 5.5 10.2 12 4.7 0.9 3.0 1 1 1 3 3 3 0 Poxvirus A6 protein DUF305 PF03713.13 RUS73577.1 - 8.6 6.5 11.8 7.8 6.6 0.3 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF305) DUF2606 PF10794.9 RUS73577.1 - 9.3 6.0 24.3 10 5.9 0.5 5.3 1 1 8 9 9 9 0 Protein of unknown function (DUF2606) DUF481 PF04338.12 RUS73578.1 - 0.18 11.8 5.7 7.8 6.4 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function, DUF481 FAM75 PF14650.6 RUS73579.1 - 0.062 12.8 22.5 0.079 12.5 11.3 2.2 2 0 0 2 2 2 0 FAM75 family DUF4834 PF16118.5 RUS73579.1 - 2.7 9.0 5.0 3.1 8.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Abhydrolase_9_N PF15420.6 RUS73579.1 - 7.3 6.5 19.1 0.61 10.1 10.6 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Tim54 PF11711.8 RUS73580.1 - 2.7e-05 23.1 9.1 4.5e-05 22.4 9.1 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2207 PF09972.9 RUS73580.1 - 0.0057 15.5 0.4 0.0079 15.0 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF5427 PF10310.9 RUS73580.1 - 0.078 11.9 18.6 0.15 11.0 18.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Connexin PF00029.19 RUS73580.1 - 0.11 12.2 14.3 0.21 11.3 14.3 1.3 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 RUS73580.1 - 0.4 9.4 6.7 0.59 8.8 6.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier AAA_11 PF13086.6 RUS73580.1 - 1 9.1 16.7 0.051 13.4 11.6 1.4 2 0 0 2 2 2 0 AAA domain DUF3807 PF12720.7 RUS73580.1 - 1.6 9.0 25.8 0.14 12.4 20.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 RUS73580.1 - 1.9 8.3 24.9 4.7 7.0 24.9 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.17 RUS73580.1 - 2.3 8.3 8.6 0.077 13.1 2.7 1.5 2 0 0 2 2 2 0 DDHD domain BORG_CEP PF14957.6 RUS73580.1 - 3.9 8.7 11.3 4.3 8.5 7.3 2.3 2 0 0 2 2 2 0 Cdc42 effector DAG_kinase_N PF14513.6 RUS73580.1 - 5 7.3 11.3 0.41 10.8 6.4 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SpoIIP PF07454.11 RUS73580.1 - 9.6 5.6 14.2 18 4.6 14.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2664 PF10867.8 RUS73583.1 - 0.0056 17.1 2.9 1 9.8 0.2 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF2664) DUF5446 PF17522.2 RUS73583.1 - 0.031 14.4 0.1 2.6e+02 1.9 0.0 4.7 5 1 0 5 5 5 0 Family of unknown function (DUF5446) Alpha_adaptinC2 PF02883.20 RUS73583.1 - 0.032 14.5 0.1 36 4.7 0.0 3.0 1 1 2 3 3 3 0 Adaptin C-terminal domain zf-C6H2 PF15801.5 RUS73583.1 - 0.041 14.2 15.9 71 3.8 0.1 6.2 1 1 4 6 6 6 0 zf-MYND-like zinc finger, mRNA-binding UNC-79 PF14776.6 RUS73583.1 - 0.068 11.9 10.1 3.1 6.5 0.2 2.8 1 1 2 3 3 3 0 Cation-channel complex subunit UNC-79 Gp49 PF05973.14 RUS73583.1 - 0.15 12.3 0.9 71 3.6 0.1 3.3 1 1 2 3 3 3 0 Phage derived protein Gp49-like (DUF891) DUF3694 PF12473.8 RUS73583.1 - 1.3 9.7 6.7 4 8.1 1.0 2.2 1 1 1 2 2 2 0 Kinesin protein Papilloma_E5A PF05776.12 RUS73583.1 - 1.5 9.3 8.9 26 5.3 0.2 4.0 1 1 5 6 6 6 0 Papillomavirus E5A protein RNA_pol_Rpc4 PF05132.14 RUS73584.1 - 0.16 12.4 5.9 0.22 11.9 5.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS73584.1 - 1.6 7.4 2.1 1.8 7.2 2.1 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RUS73584.1 - 7.2 4.8 10.7 8.3 4.6 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein IPK PF03770.16 RUS73587.1 - 2.4e-40 138.5 0.2 2.4e-40 138.5 0.2 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase Cofilin_ADF PF00241.20 RUS73589.1 - 2.2e-30 104.9 0.0 2.5e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF89 PF01937.19 RUS73590.1 - 4.4e-110 367.9 0.3 5.1e-110 367.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1204 PF06721.11 RUS73590.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) PAP2 PF01569.21 RUS73591.1 - 1.1e-14 54.4 1.8 1.1e-14 54.4 1.8 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RUS73591.1 - 0.00011 22.0 0.8 0.0003 20.6 0.8 1.9 1 0 0 1 1 1 1 PAP2 superfamily COG2 PF06148.11 RUS73592.1 - 4.9e-41 139.9 2.2 1e-40 138.9 2.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dynamitin PF04912.14 RUS73592.1 - 0.012 14.9 3.4 3 7.1 0.7 2.9 2 1 1 3 3 3 0 Dynamitin UPA_2 PF17809.1 RUS73592.1 - 0.028 14.2 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 UPA domain Vps51 PF08700.11 RUS73592.1 - 0.033 14.2 0.6 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 Vps51/Vps67 DUF1664 PF07889.12 RUS73592.1 - 0.035 14.2 2.5 0.073 13.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 RUS73592.1 - 0.037 13.5 0.2 0.072 12.6 0.2 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1943 PF09172.11 RUS73592.1 - 0.039 13.2 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Prenyltrans PF00432.21 RUS73593.1 - 5.1e-46 154.1 10.1 3.8e-09 36.1 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat HLH PF00010.26 RUS73594.1 - 9.6e-18 63.9 0.9 9.6e-18 63.9 0.9 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 RUS73594.1 - 0.0074 16.5 1.5 0.021 15.0 1.2 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper SlyX PF04102.12 RUS73594.1 - 0.032 14.9 1.0 0.069 13.8 1.0 1.7 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 RUS73594.1 - 0.068 13.0 4.2 0.14 12.0 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.19 RUS73594.1 - 1.5 6.7 6.0 1.6 6.6 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma70_ner PF04546.13 RUS73594.1 - 1.7 8.5 16.4 0.039 13.8 8.7 1.8 1 1 1 2 2 2 0 Sigma-70, non-essential region ERCC4 PF02732.15 RUS73595.1 - 2.1e-20 73.5 0.1 5.6e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 ERCC4 domain BBS1 PF14779.6 RUS73596.1 - 3.4e-113 377.3 0.1 3.4e-112 374.0 0.0 2.2 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 RUS73596.1 - 1.1e-05 25.4 0.1 0.18 11.8 0.0 3.8 2 1 3 5 5 5 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 RUS73596.1 - 3.1e-05 23.5 0.0 0.00014 21.4 0.0 1.8 1 1 0 2 2 2 1 PTHB1 N-terminus TcfC PF16967.5 RUS73596.1 - 0.03 13.8 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 0 E-set like domain PQQ_3 PF13570.6 RUS73596.1 - 0.12 12.9 0.3 88 3.8 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain DUF2420 PF10336.9 RUS73597.1 - 0.032 14.2 0.0 0.069 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2420) zf-H2C2_2 PF13465.6 RUS73598.1 - 1.6e-23 82.0 23.3 1.4e-06 28.5 1.6 5.0 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 RUS73598.1 - 6e-15 54.8 37.2 0.0002 21.6 1.0 6.1 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS73598.1 - 2.6e-09 37.1 41.8 0.0066 17.2 0.4 6.6 7 0 0 7 7 5 4 C2H2-type zinc finger zf-met PF12874.7 RUS73598.1 - 0.001 19.4 7.1 0.32 11.4 0.1 4.9 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RUS73598.1 - 0.0019 18.5 18.2 0.022 15.0 2.1 3.8 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RUS73598.1 - 0.0021 18.3 8.3 3.9 7.9 0.1 5.3 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding DUF1170 PF06663.13 RUS73598.1 - 0.028 14.2 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Actin_micro PF17003.5 RUS73598.1 - 0.036 13.3 2.0 0.096 11.8 0.0 2.4 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_aberr PF17017.5 RUS73598.1 - 0.11 12.7 12.9 0.14 12.3 0.4 4.4 2 1 2 4 4 4 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RUS73598.1 - 0.51 10.4 17.7 1.4 9.0 0.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RUS73598.1 - 5.4 7.0 11.8 19 5.3 0.1 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type CRM1_C PF08767.11 RUS73599.1 - 2.2e-129 431.2 9.2 2.2e-129 431.2 9.2 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 RUS73599.1 - 3.2e-41 140.9 17.8 3.2e-41 140.8 2.4 5.6 6 1 1 7 7 7 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 RUS73599.1 - 9.2e-37 124.5 2.3 3.6e-36 122.6 2.3 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 RUS73599.1 - 8.2e-30 102.7 0.5 8.2e-30 102.7 0.5 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 RUS73599.1 - 1.2e-18 66.3 4.4 3e-18 65.0 4.4 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 RUS73599.1 - 2.9e-12 46.3 3.0 3.7e-12 46.0 0.2 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 RUS73599.1 - 0.0016 18.4 7.0 1.6 8.6 0.0 5.1 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 RUS73599.1 - 0.0018 18.8 3.6 3 8.5 0.1 5.6 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Spc29 PF17082.5 RUS73599.1 - 0.061 13.2 1.7 0.084 12.7 0.1 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 CRM1_repeat_2 PF18784.1 RUS73600.1 - 3.1e-37 126.0 2.3 3.1e-37 126.0 2.3 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 RUS73600.1 - 3.7e-19 67.9 4.4 3.7e-19 67.9 4.4 1.8 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat BACK PF07707.15 RUS73600.1 - 0.49 10.5 6.4 5.7 7.1 2.5 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch CRM1_repeat_3 PF18787.1 RUS73600.1 - 8.4 6.6 7.6 2.4 8.4 1.5 2.7 2 1 1 3 3 3 0 CRM1 / Exportin repeat 3 UPF0564 PF10595.9 RUS73601.1 - 1.3e-58 198.8 60.8 1.3e-58 198.8 60.8 2.1 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 EZH2_WD-Binding PF11616.8 RUS73601.1 - 0.088 12.9 0.7 1.5 9.0 0.1 2.7 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Thioesterase PF00975.20 RUS73601.1 - 2 8.5 6.8 2 8.5 0.1 3.4 4 0 0 4 4 4 0 Thioesterase domain FAD_binding_3 PF01494.19 RUS73602.1 - 8e-21 74.7 0.0 2.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 RUS73602.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 RUS73602.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS73602.1 - 0.017 14.7 0.5 0.058 13.0 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 RUS73602.1 - 0.046 12.6 0.2 4 6.2 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 RUS73602.1 - 0.087 13.4 0.3 6.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 RUS73603.1 - 2.7e-33 114.1 0.8 7.3e-12 45.4 0.1 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73603.1 - 2.1e-20 71.6 7.3 0.001 18.8 0.0 7.5 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 RUS73603.1 - 4.9e-19 67.6 1.0 0.16 11.9 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 RUS73603.1 - 1.6e-15 55.9 1.8 0.014 15.4 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS73603.1 - 2.6e-15 55.2 13.6 0.0053 16.8 0.0 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS73603.1 - 1.1e-11 43.9 7.3 0.18 12.1 0.0 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73603.1 - 1.4e-11 44.1 0.3 2.2 9.3 0.0 8.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS73603.1 - 3e-08 34.1 8.0 0.041 14.4 0.0 6.2 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS73603.1 - 2.9e-07 30.2 1.9 7.4e-06 25.6 0.5 3.1 1 1 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 RUS73603.1 - 2.7e-05 24.7 0.9 9.7 6.9 0.0 6.0 6 2 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 RUS73603.1 - 0.0012 18.9 2.2 20 5.7 0.0 5.9 5 0 0 5 5 5 0 PPR repeat ANAPC3 PF12895.7 RUS73603.1 - 0.0016 18.6 8.3 3.1 8.1 0.6 5.4 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RUS73603.1 - 0.0053 17.3 7.8 10 7.0 0.0 7.3 8 1 0 8 8 8 1 Tetratricopeptide repeat Coatomer_E PF04733.14 RUS73603.1 - 0.007 15.8 5.1 1.7 8.0 0.0 4.2 3 2 2 5 5 5 2 Coatomer epsilon subunit DnaG_DnaB_bind PF08278.11 RUS73603.1 - 0.022 15.4 1.9 0.14 12.8 0.1 2.9 4 0 0 4 4 3 0 DNA primase DnaG DnaB-binding PPR_2 PF13041.6 RUS73603.1 - 0.16 12.2 1.5 87 3.4 0.0 4.4 4 0 0 4 4 4 0 PPR repeat family TPR_17 PF13431.6 RUS73603.1 - 0.17 12.3 1.0 5.6e+02 1.3 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat AIG1 PF04548.16 RUS73604.1 - 1.6e-15 57.1 0.0 2.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS73604.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2371 PF10177.9 RUS73604.1 - 0.096 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Jnk-SapK_ap_N PF09744.9 RUS73604.1 - 2.1 8.5 7.8 2.9 8.1 0.7 2.3 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 PX PF00787.24 RUS73606.1 - 4.4e-19 68.5 0.0 8.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Rootletin PF15035.6 RUS73606.1 - 0.0068 16.5 1.3 0.014 15.4 1.3 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF641 PF04859.12 RUS73606.1 - 0.091 13.1 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Uds1 PF15456.6 RUS73606.1 - 0.19 11.9 1.7 0.27 11.4 0.6 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Fez1 PF06818.15 RUS73606.1 - 0.62 10.5 4.2 2.6 8.4 4.4 2.0 2 1 0 2 2 2 0 Fez1 SOGA PF11365.8 RUS73606.1 - 1.4 10.0 6.3 2.2 9.5 3.2 2.3 2 0 0 2 2 2 0 Protein SOGA CENP-F_leu_zip PF10473.9 RUS73606.1 - 4 7.5 9.6 5.1 7.1 6.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.7 RUS73607.1 - 1.3e-46 157.0 19.2 3.6e-11 43.5 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS73607.1 - 3.5e-41 134.5 22.8 0.0048 17.3 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 RUS73607.1 - 9e-41 137.8 20.9 1.4e-05 25.5 0.1 10.0 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RUS73607.1 - 2.5e-35 119.4 29.5 2.8e-05 24.3 0.2 11.2 10 1 1 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 RUS73607.1 - 7.8e-34 115.3 20.1 3.5e-09 36.7 0.4 7.7 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Trypsin_2 PF13365.6 RUS73608.1 - 2.3e-05 25.3 0.0 4.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Cadherin PF00028.17 RUS73609.1 - 3.4e-123 402.4 35.7 3.7e-13 49.7 0.1 14.7 14 0 0 14 14 14 13 Cadherin domain Cadherin_3 PF16184.5 RUS73609.1 - 8.5e-08 32.2 24.5 0.0092 16.0 0.0 10.5 11 0 0 11 11 11 2 Cadherin-like Cadherin_2 PF08266.12 RUS73609.1 - 0.00045 20.0 0.1 0.55 10.1 0.0 4.6 5 0 0 5 5 5 1 Cadherin-like Shisa PF13908.6 RUS73609.1 - 0.0097 16.2 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 RUS73609.1 - 0.016 14.0 0.2 0.079 11.8 0.0 2.1 3 0 0 3 3 3 0 Amnionless TMEM154 PF15102.6 RUS73609.1 - 0.039 13.9 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 RUS73609.1 - 0.076 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Transmembrane 52 Orf78 PF06024.12 RUS73609.1 - 0.14 12.5 0.3 0.37 11.1 0.3 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Comm PF15957.5 RUS73609.1 - 0.16 12.3 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 Commissureless SusE PF14292.6 RUS73609.1 - 0.64 10.3 3.6 1.6 9.0 0.1 3.4 3 0 0 3 3 3 0 SusE outer membrane protein Cadherin PF00028.17 RUS73610.1 - 4.2e-95 312.4 35.0 3.7e-16 59.3 0.0 11.9 11 2 0 11 11 11 10 Cadherin domain Cadherin_3 PF16184.5 RUS73610.1 - 8e-06 25.8 22.4 0.18 11.8 0.4 8.6 8 1 0 8 8 8 3 Cadherin-like Y_Y_Y PF07495.13 RUS73610.1 - 0.00012 22.0 2.6 25 4.9 0.1 6.8 6 1 0 6 6 6 2 Y_Y_Y domain Cadherin_pro PF08758.11 RUS73610.1 - 0.011 15.8 0.2 41 4.4 0.0 4.8 5 0 0 5 5 5 0 Cadherin prodomain like Filamin PF00630.19 RUS73610.1 - 0.15 12.9 0.1 0.15 12.9 0.1 5.0 4 2 0 4 4 4 0 Filamin/ABP280 repeat Cadherin PF00028.17 RUS73611.1 - 8.4e-24 83.8 1.5 1.1e-10 41.8 0.1 3.9 2 1 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 RUS73611.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Cadherin-like Baculo_11_kDa PF06143.11 RUS73611.1 - 0.1 12.2 3.7 0.31 10.6 3.7 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cadherin_3 PF16184.5 RUS73611.1 - 0.11 12.5 2.1 15 5.6 0.3 3.1 2 1 1 3 3 3 0 Cadherin-like TMEM52 PF14979.6 RUS73611.1 - 0.18 11.7 2.3 0.2 11.6 0.4 2.0 3 0 0 3 3 3 0 Transmembrane 52 SCIMP PF15050.6 RUS73611.1 - 2.4 8.6 5.5 7.4 7.0 5.5 1.8 1 0 0 1 1 1 0 SCIMP protein Chordopox_A13L PF05961.11 RUS73611.1 - 4.8 7.5 6.4 9.3 6.6 5.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein HLH PF00010.26 RUS73612.1 - 2.6e-17 62.5 0.8 4e-17 61.9 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PHC2_SAM_assoc PF16616.5 RUS73613.1 - 6.3 7.6 8.4 7.6 7.4 0.7 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Raptor_N PF14538.6 RUS73614.1 - 4.8e-71 237.5 0.0 9.5e-71 236.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.6 RUS73614.1 - 3.9e-12 46.4 0.1 8.7e-05 22.8 0.0 3.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 RUS73614.1 - 1.9e-11 43.2 3.4 0.00029 20.8 0.0 5.3 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 RUS73614.1 - 1.2e-09 38.6 3.3 0.5 11.3 0.1 7.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Cnd1 PF12717.7 RUS73614.1 - 1.1e-05 25.5 0.0 0.00014 21.9 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS73614.1 - 0.00012 22.4 0.2 0.014 15.9 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Tetraspanin PF00335.20 RUS73615.1 - 8e-46 156.6 3.5 9.9e-46 156.3 3.5 1.1 1 0 0 1 1 1 1 Tetraspanin family LtrA PF06772.11 RUS73615.1 - 0.0066 15.7 5.5 0.0066 15.7 5.5 1.4 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) CcmF_C PF16327.5 RUS73615.1 - 0.096 11.9 2.6 0.15 11.3 2.6 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal CD20 PF04103.15 RUS73615.1 - 1.8 8.6 8.8 2.2 8.3 7.9 1.8 2 1 0 2 2 2 0 CD20-like family Sid-5 PF17204.3 RUS73615.1 - 2.6 8.3 4.8 9.9 6.4 0.9 2.3 2 0 0 2 2 2 0 Sid-5 family DUF2046 PF09755.9 RUS73616.1 - 6e-153 508.4 52.1 7.2e-153 508.2 52.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) MCC-bdg_PDZ PF10506.9 RUS73616.1 - 0.0059 16.6 1.8 0.0059 16.6 1.8 5.3 4 2 2 6 6 6 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.9 RUS73616.1 - 0.059 12.4 47.2 5 6.1 33.9 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Enterotoxin_b PF01376.18 RUS73616.1 - 0.12 12.6 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain LPP PF04728.13 RUS73616.1 - 8.2 6.9 13.1 17 5.9 0.4 4.8 3 2 2 5 5 5 0 Lipoprotein leucine-zipper ATG16 PF08614.11 RUS73616.1 - 8.2 6.6 57.4 6.1 7.0 13.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GCS PF03074.16 RUS73617.1 - 1.6e-154 514.7 0.0 2.2e-154 514.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 RUS73617.1 - 0.018 14.4 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) SANT_DAMP1_like PF16282.5 RUS73617.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Cys_rich_KTR PF14205.6 RUS73618.1 - 0.00092 19.0 11.5 20 5.1 0.1 6.8 1 1 7 8 8 8 1 Cysteine-rich KTR RPOL_N PF14700.6 RUS73618.1 - 0.015 14.7 1.9 0.62 9.4 0.7 2.7 1 1 1 2 2 2 0 DNA-directed RNA polymerase N-terminal SHP PF03579.13 RUS73618.1 - 0.75 9.8 18.0 45 4.1 0.1 6.9 2 1 6 8 8 8 0 Small hydrophobic protein zf-H2C2_5 PF13909.6 RUS73618.1 - 2.8 7.8 20.2 43 4.0 0.1 6.9 7 0 0 7 7 7 0 C2H2-type zinc-finger domain SNN_cytoplasm PF09051.10 RUS73618.1 - 9.9 6.1 8.8 2.7e+02 1.5 0.1 5.4 7 0 0 7 7 7 0 Stannin cytoplasmic Viral_cys_rich PF08008.12 RUS73619.1 - 7.9e-06 25.8 0.4 9.1 6.4 0.0 4.7 1 1 4 5 5 5 5 Viral cysteine rich GyrB_insert PF18053.1 RUS73619.1 - 0.00013 21.9 0.5 5.3 6.9 0.0 3.0 1 1 2 3 3 3 3 DNA gyrase B subunit insert domain DUF3926 PF13080.6 RUS73619.1 - 0.00032 20.5 5.8 40 4.3 0.0 5.0 1 1 4 5 5 5 0 Protein of unknown function (DUF3926) Gp5_C PF06715.12 RUS73619.1 - 0.0029 17.6 9.5 20 5.6 0.2 5.1 1 1 4 5 5 5 0 Gp5 C-terminal repeat (3 copies) S4_2 PF13275.6 RUS73619.1 - 0.0032 17.2 0.2 3.2 7.6 0.1 3.1 1 1 3 4 4 4 1 S4 domain Adenine_glyco PF03352.13 RUS73619.1 - 0.011 15.5 4.9 0.27 11.0 2.1 2.7 1 1 1 2 2 2 0 Methyladenine glycosylase Imm74 PF15603.6 RUS73619.1 - 0.06 13.6 0.1 20 5.4 0.0 2.4 1 1 3 4 4 4 0 Immunity protein 74 DUF2345 PF10106.9 RUS73619.1 - 0.18 11.7 4.8 1.8 8.4 1.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Glyco_transf_41 PF13844.6 RUS73619.1 - 0.52 8.7 8.6 0.8 8.1 8.6 1.3 1 1 0 1 1 1 0 Glycosyl transferase family 41 zf-U11-48K PF05253.12 RUS73619.1 - 3 7.9 10.5 1.9e+02 2.1 0.1 5.2 5 0 0 5 5 5 0 U11-48K-like CHHC zinc finger OATP PF03137.20 RUS73620.1 - 9.9e-101 337.7 17.0 1.7e-80 270.9 13.5 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS73620.1 - 4.8e-09 35.6 18.1 9.4e-06 24.8 8.9 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS73620.1 - 1.1e-07 31.9 4.5 3.4e-07 30.3 4.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Nop14 PF04147.12 RUS73620.1 - 0.0016 16.8 14.8 0.002 16.5 14.8 1.0 1 0 0 1 1 1 1 Nop14-like family Tim54 PF11711.8 RUS73620.1 - 0.0033 16.3 3.5 0.0044 15.9 3.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 YL1 PF05764.13 RUS73620.1 - 0.0071 16.5 19.8 0.0094 16.1 19.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Kazal_1 PF00050.21 RUS73620.1 - 0.022 14.8 6.4 0.067 13.2 6.4 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Connexin PF00029.19 RUS73620.1 - 0.59 9.8 7.0 1 9.1 7.0 1.3 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RUS73620.1 - 1 7.5 19.8 1.4 7.2 19.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FmiP_Thoc5 PF09766.9 RUS73620.1 - 2.8 7.1 9.7 3.9 6.7 9.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 CPSF100_C PF13299.6 RUS73620.1 - 5.2 7.2 11.3 7.8 6.6 11.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop53 PF07767.11 RUS73620.1 - 6.1 6.1 29.6 7.9 5.8 29.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.12 RUS73620.1 - 8.1 6.6 9.1 11 6.2 9.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 RUS73620.1 - 8.7 5.2 5.8 12 4.7 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SPT6_acidic PF14632.6 RUS73620.1 - 10 6.8 31.9 17 6.1 31.9 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Reprolysin PF01421.19 RUS73621.1 - 2.6e-12 47.1 0.1 4.1e-12 46.4 0.1 1.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS73621.1 - 1.4e-10 41.6 0.2 2.3e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS73621.1 - 3.8e-10 40.3 0.4 8.8e-10 39.2 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS73621.1 - 5.1e-08 33.0 3.6 4.2e-07 30.0 3.6 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS73621.1 - 1.9e-07 31.0 4.5 1.2e-06 28.3 4.5 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS73621.1 - 0.0067 16.3 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.11 RUS73621.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Acetyltransf_1 PF00583.25 RUS73623.1 - 0.00018 21.7 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS73623.1 - 0.0076 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS73623.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Apolipoprotein PF01442.18 RUS73624.1 - 0.0017 18.3 1.6 0.0053 16.7 0.6 2.1 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS73624.1 - 0.0074 16.3 21.0 0.12 12.4 0.1 3.9 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 RUS73624.1 - 0.18 10.3 1.3 0.31 9.5 1.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 RUS73624.1 - 0.47 10.6 5.9 5.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 RUS73624.1 - 1.1 8.8 4.7 8.3 5.9 5.2 2.2 2 1 0 2 2 2 0 Exonuclease VII, large subunit Allexi_40kDa PF05549.11 RUS73624.1 - 2.1 7.8 6.9 24 4.3 3.9 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein I-set PF07679.16 RUS73625.1 - 2.3e-11 43.6 3.9 6.5e-07 29.3 0.1 3.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS73625.1 - 5.8e-11 42.8 9.6 4e-07 30.5 0.7 4.5 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RUS73625.1 - 2e-08 34.4 5.6 8.4e-06 26.0 0.4 4.2 3 0 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 RUS73625.1 - 1.7e-05 24.9 3.8 0.0025 17.9 0.6 3.7 3 0 0 3 3 3 1 Immunoglobulin domain fn3 PF00041.21 RUS73625.1 - 8.3e-05 22.9 0.1 0.00097 19.4 0.0 2.8 3 0 0 3 3 3 1 Fibronectin type III domain C2-set_2 PF08205.12 RUS73625.1 - 0.00012 22.1 3.4 0.51 10.4 0.0 4.0 3 1 1 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 RUS73625.1 - 0.00044 20.2 0.2 0.0047 16.9 0.1 2.7 3 0 0 3 3 3 1 C17orf99 Ig domain V-set PF07686.17 RUS73625.1 - 0.0034 17.5 0.3 5.9 7.1 0.1 3.6 1 1 1 2 2 2 2 Immunoglobulin V-set domain EphA2_TM PF14575.6 RUS73625.1 - 0.005 17.7 0.0 0.02 15.7 0.0 2.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain MBG PF17883.1 RUS73625.1 - 0.083 13.5 2.2 0.15 12.6 0.1 2.6 2 0 0 2 2 2 0 MBG domain Adeno_E3_CR2 PF02439.15 RUS73625.1 - 0.14 12.0 0.2 0.39 10.5 0.2 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Neur_chan_memb PF02932.16 RUS73625.1 - 0.3 11.1 1.6 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Miff PF05644.11 RUS73625.1 - 7.8 6.0 10.9 4.8 6.7 2.0 2.3 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF4510 PF14971.6 RUS73626.1 - 0.092 13.1 1.0 0.19 12.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) OmpH PF03938.14 RUS73626.1 - 0.32 11.3 7.9 0.57 10.5 7.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RHINO PF15319.6 RUS73627.1 - 2.3 8.2 6.5 0.52 10.3 3.3 1.5 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF4801 PF16059.5 RUS73628.1 - 1.4e-13 50.5 17.5 1.6e-13 50.4 6.7 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4801) TraS PF10624.9 RUS73628.1 - 0.2 11.6 0.5 0.37 10.7 0.5 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Nt_Gln_amidase PF09764.9 RUS73629.1 - 5.4e-68 228.2 1.1 6.2e-68 228.0 1.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Gln_deamidase_2 PF18626.1 RUS73629.1 - 0.017 15.4 0.6 0.026 14.8 0.6 1.3 1 0 0 1 1 1 0 Glutaminase PCMT PF01135.19 RUS73630.1 - 3.1e-80 268.9 0.0 3.7e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RUS73630.1 - 2.3e-07 30.8 0.0 5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS73630.1 - 8.9e-06 26.3 0.0 1.6e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS73630.1 - 1.8e-05 25.3 0.0 4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS73630.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 RUS73630.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 RUS73630.1 - 0.00038 20.5 0.1 0.00059 19.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS73630.1 - 0.0021 17.7 0.2 0.0052 16.3 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RUS73630.1 - 0.0039 17.1 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS73630.1 - 0.022 14.6 0.0 0.057 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 RUS73630.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 RUS73630.1 - 0.067 13.3 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase GCD14 PF08704.10 RUS73630.1 - 0.084 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MANEC PF07502.14 RUS73631.1 - 6.7e-14 51.9 4.9 1.6e-13 50.7 4.9 1.6 1 0 0 1 1 1 1 MANEC domain Ldl_recept_a PF00057.18 RUS73631.1 - 5.8e-06 26.4 4.7 5.8e-06 26.4 4.7 2.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A EB PF01683.18 RUS73631.1 - 0.00011 22.5 4.8 0.00011 22.5 4.8 3.2 3 0 0 3 3 3 1 EB module PP1_inhibitor PF05361.12 RUS73632.1 - 1.5e-11 44.4 2.9 1.8e-11 44.2 2.9 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Ribosomal_L27e PF01777.18 RUS73632.1 - 0.011 16.1 1.8 0.011 16.1 1.8 2.1 2 1 0 2 2 2 0 Ribosomal L27e protein family RLL PF10036.9 RUS73633.1 - 1.9e-36 126.3 0.0 2.2e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein PAN_3 PF08277.12 RUS73635.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain IP_trans PF02121.18 RUS73636.1 - 1.5e-107 358.8 0.1 2.2e-107 358.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 RUS73636.1 - 2.7e-41 142.2 2.4 1.9e-40 139.4 0.4 2.9 2 1 0 2 2 2 1 DDHD domain LNS2 PF08235.13 RUS73636.1 - 0.0001 21.8 0.1 0.0059 16.1 0.1 2.3 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF1397 PF07165.11 RUS73637.1 - 0.00094 18.6 8.8 0.0014 18.0 8.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) CPG4 PF15481.6 RUS73637.1 - 0.011 16.3 7.7 0.013 16.1 2.1 2.4 2 1 0 2 2 2 0 Chondroitin proteoglycan 4 DUF19 PF01579.18 RUS73637.1 - 1.5 8.6 9.6 9.2 6.0 9.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF19) FYRC PF05965.14 RUS73638.1 - 2e-19 69.5 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 RUS73638.1 - 4.3e-18 64.9 0.2 6.8e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus EXS PF03124.14 RUS73639.1 - 1.5e-104 349.9 24.5 2.2e-104 349.3 24.5 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 RUS73639.1 - 1.4e-30 107.5 18.1 1.9e-15 57.7 0.4 3.1 1 1 2 3 3 3 3 SPX domain CNH PF00780.22 RUS73639.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 CNH domain 3-alpha PF03475.14 RUS73640.1 - 0.029 14.2 0.2 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 3-alpha domain OST3_OST6 PF04756.13 RUS73641.1 - 1.5e-09 37.6 0.1 1.7e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DmsC PF04976.12 RUS73641.1 - 0.03 13.8 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) LapA_dom PF06305.11 RUS73641.1 - 0.28 11.0 1.1 0.7 9.7 1.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3487 PF11990.8 RUS73641.1 - 2 8.4 4.1 0.34 10.8 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Ig_3 PF13927.6 RUS73642.1 - 4.7e-22 78.4 1.9 2.6e-08 34.3 0.1 4.9 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 RUS73642.1 - 4.3e-19 68.6 7.1 1.3e-11 44.6 0.1 5.9 4 2 1 5 5 5 3 Immunoglobulin domain I-set PF07679.16 RUS73642.1 - 5.3e-15 55.3 0.3 8.4e-05 22.6 0.0 5.3 4 1 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 RUS73642.1 - 7.7e-10 38.9 2.9 0.39 10.9 0.0 6.1 5 2 1 6 6 6 4 Immunoglobulin V-set domain ig PF00047.25 RUS73642.1 - 4.3e-09 36.4 6.5 0.0074 16.4 0.0 5.6 5 1 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS73642.1 - 1e-06 28.7 0.0 0.3 11.2 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain fn3 PF00041.21 RUS73642.1 - 0.0007 19.9 0.0 2.3 8.6 0.0 3.4 3 0 0 3 3 3 2 Fibronectin type III domain Ig_4 PF16680.5 RUS73642.1 - 0.00076 19.7 0.0 0.0085 16.3 0.0 3.0 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain zf-C4 PF00105.18 RUS73646.1 - 8.4e-18 64.6 10.9 2.7e-17 63.0 10.9 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Med22 PF06179.12 RUS73646.1 - 1.6e-09 37.9 0.5 4.6e-09 36.4 0.5 1.7 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex HSA PF07529.13 RUS73647.1 - 0.94 9.8 9.9 11 6.4 3.3 3.3 3 0 0 3 3 3 0 HSA Trypan_PARP PF05887.11 RUS73647.1 - 5.8 6.9 9.8 18 5.3 0.1 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1016_N PF17761.1 RUS73648.1 - 0.82 9.8 4.8 4.1 7.6 0.8 3.0 2 1 1 3 3 3 0 DUF1016 N-terminal domain JAB PF01398.21 RUS73648.1 - 1.3 9.0 15.3 20 5.2 0.1 5.0 2 2 3 5 5 5 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Kazal_2 PF07648.15 RUS73649.1 - 1.7e-11 44.0 7.1 5.9e-07 29.5 1.2 2.5 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS73649.1 - 3e-10 39.9 8.1 6.9e-05 22.8 0.6 2.8 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain TPR_12 PF13424.6 RUS73651.1 - 3.1e-96 315.8 101.5 3.2e-11 43.4 0.6 15.2 8 3 8 18 18 18 15 Tetratricopeptide repeat TPR_7 PF13176.6 RUS73651.1 - 9.7e-83 266.3 69.6 1e-05 25.2 0.0 22.4 22 1 1 23 23 22 16 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73651.1 - 2e-70 229.9 67.3 0.00018 21.2 2.2 22.2 24 0 0 24 24 23 16 Tetratricopeptide repeat CHAT PF12770.7 RUS73651.1 - 1.3e-54 185.6 0.0 4.6e-54 183.8 0.0 2.0 1 1 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 RUS73651.1 - 1e-52 171.9 59.0 0.00029 20.8 0.9 22.9 24 0 0 24 24 23 13 Tetratricopeptide repeat TPR_2 PF07719.17 RUS73651.1 - 5.7e-49 160.3 77.3 0.00048 20.0 0.1 22.3 23 0 0 23 23 22 15 Tetratricopeptide repeat TPR_10 PF13374.6 RUS73651.1 - 2.2e-40 135.4 74.5 0.0028 17.5 0.4 22.7 24 0 0 24 24 24 11 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS73651.1 - 7.4e-20 71.6 61.5 8.6e-05 22.1 1.2 8.0 2 1 6 8 8 8 7 MalT-like TPR region TPR_14 PF13428.6 RUS73651.1 - 3.5e-12 46.1 51.7 3.8 8.6 0.4 19.3 18 4 4 22 22 20 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 RUS73651.1 - 3.9e-11 42.9 19.4 0.048 13.8 0.1 11.9 7 3 7 14 14 13 2 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 RUS73651.1 - 1.3e-07 31.8 25.9 30 5.5 0.0 14.8 16 0 0 16 16 13 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS73651.1 - 1.8e-06 28.4 51.9 0.0048 17.4 0.7 12.6 5 4 8 14 14 13 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS73651.1 - 5.6e-06 26.9 53.2 1.5 9.5 0.0 15.6 11 5 4 16 16 15 3 Tetratricopeptide repeat TPR_4 PF07721.14 RUS73651.1 - 3.2e-05 24.2 56.4 4.1 8.3 0.1 16.0 17 0 0 17 17 15 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS73651.1 - 4e-05 23.2 35.4 20 5.0 0.1 16.1 17 3 2 19 19 19 0 TPR repeat RPN7 PF10602.9 RUS73651.1 - 0.00023 20.9 23.1 0.003 17.3 0.6 7.6 6 3 2 8 8 8 1 26S proteasome subunit RPN7 ANAPC5 PF12862.7 RUS73651.1 - 0.0032 17.5 32.1 1.4 9.1 0.4 11.5 6 4 3 10 10 10 1 Anaphase-promoting complex subunit 5 TPR_15 PF13429.6 RUS73651.1 - 0.027 13.7 0.2 0.027 13.7 0.2 5.4 6 2 2 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 RUS73651.1 - 0.077 13.3 10.7 37 4.9 0.1 7.6 9 0 0 9 9 5 0 PPR repeat DUF2225 PF09986.9 RUS73651.1 - 0.085 12.6 6.6 8.8 6.0 0.0 4.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3856 PF12968.7 RUS73651.1 - 0.4 10.7 25.0 31 4.6 0.0 10.1 5 3 4 11 11 11 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 RUS73651.1 - 0.78 9.9 37.6 0.19 11.9 0.3 9.8 9 1 1 11 11 11 0 Tetratricopeptide repeat TPR_17 PF13431.6 RUS73651.1 - 1.3 9.5 43.8 27 5.5 0.0 14.5 18 0 0 18 18 16 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RUS73651.1 - 4.8 7.1 5.6 8.6 6.2 0.1 3.4 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal MIT PF04212.18 RUS73651.1 - 7.3 6.7 12.4 1.4 9.1 0.1 5.9 8 0 0 8 8 6 0 MIT (microtubule interacting and transport) domain Mucin-like PF16058.5 RUS73653.1 - 0.00042 20.3 0.0 5.6 7.1 0.0 3.5 1 1 3 4 4 4 4 Mucin-like 4HPAD_g_N PF18671.1 RUS73653.1 - 0.083 12.6 23.5 99 2.8 0.3 12.4 15 2 6 21 21 21 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Zn_ribbon_17 PF17120.5 RUS73653.1 - 0.26 10.9 14.6 11 5.8 1.1 4.4 2 2 3 5 5 5 0 Zinc-ribbon, C4HC2 type VIT_2 PF13757.6 RUS73653.1 - 2.7 8.0 44.7 21 5.1 0.3 9.0 1 1 13 14 14 14 0 Vault protein inter-alpha-trypsin domain Pkinase PF00069.25 RUS73654.1 - 4.8e-66 222.8 0.0 3.8e-65 219.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73654.1 - 4.4e-33 114.6 2.5 1.4e-32 113.0 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 RUS73654.1 - 0.0029 17.6 0.1 0.0029 17.6 0.1 3.0 1 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS73654.1 - 0.018 14.0 17.5 0.078 11.9 17.4 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Ndc1_Nup PF09531.10 RUS73654.1 - 2.2 6.9 15.3 2.7 6.6 15.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Miga PF10265.9 RUS73654.1 - 8.2 5.3 9.8 12 4.7 9.8 1.2 1 0 0 1 1 1 0 Mitoguardin PAP_assoc PF03828.19 RUS73655.1 - 1.6e-05 25.0 0.1 4.2e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_assoc PF03828.19 RUS73657.1 - 1.1e-06 28.7 0.0 3.6e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-C2H2_jaz PF12171.8 RUS73657.1 - 0.0002 21.5 14.5 0.00063 20.0 14.5 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS73657.1 - 0.00024 21.4 8.0 0.00081 19.7 8.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PAP_central PF04928.17 RUS73657.1 - 0.0005 19.1 0.7 0.0043 16.1 0.0 2.5 2 1 0 2 2 2 1 Poly(A) polymerase central domain zf-C2H2_2 PF12756.7 RUS73657.1 - 0.002 18.4 3.3 0.0076 16.6 3.3 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NTP_transf_2 PF01909.23 RUS73657.1 - 0.013 15.8 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF4187 PF13821.6 RUS73657.1 - 0.034 13.9 1.5 0.12 12.1 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-DBF PF07535.12 RUS73657.1 - 2.1 8.5 7.6 5.3 7.2 7.6 1.7 1 0 0 1 1 1 0 DBF zinc finger FYVE PF01363.21 RUS73658.1 - 4.8e-17 61.9 3.9 4.8e-17 61.9 3.9 2.4 2 1 0 2 2 2 1 FYVE zinc finger RUN PF02759.19 RUS73658.1 - 2.5e-08 34.0 0.0 2.5e-08 34.0 0.0 3.6 4 0 0 4 4 4 1 RUN domain APG6_N PF17675.1 RUS73658.1 - 0.00026 21.5 29.3 0.00026 21.5 29.3 13.3 2 2 10 12 12 12 1 Apg6 coiled-coil region Fez1 PF06818.15 RUS73658.1 - 0.0004 20.9 22.6 0.0004 20.9 22.6 8.7 1 1 6 8 8 8 2 Fez1 GOLD_2 PF13897.6 RUS73658.1 - 0.00082 19.9 0.1 0.00082 19.9 0.1 7.6 7 3 2 9 9 9 1 Golgi-dynamics membrane-trafficking IBR PF01485.21 RUS73658.1 - 0.22 11.8 6.2 0.82 9.9 6.2 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RUS73658.1 - 7 7.1 8.9 20 5.6 8.9 1.8 1 0 0 1 1 1 0 Ring finger domain adh_short_C2 PF13561.6 RUS73659.1 - 9.7e-27 94.0 0.2 1.1e-26 93.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS73659.1 - 1.5e-08 34.3 0.3 2.1e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RsdA_SigD_bd PF16751.5 RUS73660.1 - 0.00031 20.9 22.4 13 6.2 0.2 6.9 7 0 0 7 7 7 5 Anti-sigma-D factor RsdA to sigma factor binding region Phage_TTP_12 PF16461.5 RUS73660.1 - 0.00038 20.1 2.7 2.5 7.8 0.1 4.1 1 1 4 5 5 5 4 Lambda phage tail tube protein, TTP Latexin PF06907.12 RUS73660.1 - 5.6 6.4 14.8 35 3.8 0.2 5.7 1 1 6 7 7 7 0 Latexin Mhr1 PF12829.7 RUS73662.1 - 0.00055 20.0 0.0 1.3e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Transcriptional regulation of mitochondrial recombination Ependymin PF00811.18 RUS73662.1 - 0.0017 18.6 0.1 58 4.0 0.0 3.9 1 1 3 4 4 4 1 Ependymin COQ7 PF03232.13 RUS73662.1 - 0.078 12.7 0.6 88 2.8 0.0 3.7 1 1 4 5 5 5 0 Ubiquinone biosynthesis protein COQ7 P4Ha_N PF08336.11 RUS73664.1 - 6.8e-10 39.1 16.9 0.042 13.9 0.0 5.3 1 1 3 4 4 4 4 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fz PF01392.22 RUS73665.1 - 3.5e-20 72.7 1.7 4e-20 72.5 1.7 1.0 1 0 0 1 1 1 1 Fz domain SAMP PF05924.11 RUS73666.1 - 0.0026 17.0 27.5 20 4.6 0.1 7.9 8 0 0 8 8 8 7 SAMP Motif SRCR_2 PF15494.6 RUS73667.1 - 7.8e-13 48.8 0.1 1e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.18 RUS73667.1 - 3.6e-07 30.6 0.6 5.5e-07 30.0 0.4 1.5 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS73667.1 - 1.1e-06 29.1 0.1 2e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Hepsin, SRCR domain Ldl_recept_a PF00057.18 RUS73667.1 - 0.0044 17.2 5.4 0.0044 17.2 5.4 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A SCAN PF02023.17 RUS73668.1 - 8.4e-08 31.9 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SCAN domain DUF5363 PF17320.2 RUS73668.1 - 0.021 14.7 0.2 0.06 13.2 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5363) Cornifin PF02389.15 RUS73669.1 - 0.066 13.4 3.8 0.087 13.0 3.8 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family PDZ PF00595.24 RUS73670.1 - 1.9e-41 140.3 0.1 1.2e-13 51.2 0.1 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RUS73670.1 - 4.6e-19 68.0 0.0 3.6e-06 26.7 0.0 4.8 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 RUS73670.1 - 6.3e-10 39.2 0.0 0.019 15.3 0.0 4.2 4 0 0 4 4 4 2 PDZ domain Cep57_CLD_2 PF14197.6 RUS73670.1 - 0.0012 18.9 4.4 0.0012 18.9 4.4 7.1 3 1 4 7 7 7 2 Centrosome localisation domain of PPC89 APG6_N PF17675.1 RUS73670.1 - 0.16 12.5 72.9 0.73 10.4 18.0 5.7 4 1 1 5 5 5 0 Apg6 coiled-coil region Drf_FH1 PF06346.12 RUS73671.1 - 1.4e-05 24.9 25.4 0.017 14.8 11.6 2.3 1 1 1 2 2 2 2 Formin Homology Region 1 PLAT PF01477.23 RUS73674.1 - 2.3e-101 334.5 6.8 1.6e-15 57.7 0.3 8.1 8 0 0 8 8 8 8 PLAT/LH2 domain ATS3 PF06232.11 RUS73674.1 - 0.00014 21.8 0.0 0.37 10.7 0.0 4.5 6 0 0 6 6 6 1 Embryo-specific protein 3, (ATS3) Lactamase_B_5 PF14597.6 RUS73674.1 - 0.11 12.0 0.0 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily SSL_OB PF09199.10 RUS73674.1 - 0.15 12.4 0.2 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Staphylococcal superantigen-like OB-fold domain DUF2914 PF11141.8 RUS73674.1 - 0.19 11.5 1.8 4.5 7.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) DUF3563 PF12086.8 RUS73674.1 - 0.19 11.5 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) PLAT PF01477.23 RUS73675.1 - 6.8e-69 229.8 0.0 1.7e-20 73.8 0.0 5.1 5 0 0 5 5 5 5 PLAT/LH2 domain PLAT PF01477.23 RUS73676.1 - 1.6e-93 309.2 0.6 6.7e-21 75.0 0.0 6.6 6 0 0 6 6 6 6 PLAT/LH2 domain DCX PF03607.17 RUS73676.1 - 9.4e-33 112.1 0.0 1.2e-18 67.0 0.0 3.1 3 0 0 3 3 3 2 Doublecortin FGF PF00167.18 RUS73676.1 - 1.4e-09 38.1 0.0 6.9e-05 23.0 0.0 3.8 2 1 1 3 3 3 2 Fibroblast growth factor Calpain_III PF01067.22 RUS73676.1 - 0.019 15.2 0.1 0.049 13.9 0.1 1.7 1 0 0 1 1 1 0 Calpain large subunit, domain III Ctr PF04145.15 RUS73677.1 - 1.1e-23 84.5 13.7 4.5e-14 53.3 11.6 2.3 1 1 1 2 2 2 2 Ctr copper transporter family FA_desaturase PF00487.24 RUS73677.1 - 0.04 13.7 2.0 0.051 13.4 2.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF1516 PF07457.11 RUS73677.1 - 0.12 12.6 4.8 0.2 11.8 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1516) DUF2897 PF11446.8 RUS73677.1 - 0.25 11.3 2.3 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) FlaC_arch PF05377.11 RUS73679.1 - 2.6e-05 24.5 1.9 2 8.9 0.1 4.7 1 1 2 3 3 3 2 Flagella accessory protein C (FlaC) DUF16 PF01519.16 RUS73679.1 - 0.027 15.0 0.0 4.1 8.0 0.0 3.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 MSP1b PF03429.13 RUS73679.1 - 0.068 11.3 17.2 2.5 6.1 0.8 4.4 1 1 3 4 4 4 0 Major surface protein 1B DASH_Spc19 PF08287.11 RUS73679.1 - 0.09 12.7 0.2 37 4.2 0.1 3.9 1 1 3 4 4 4 0 Spc19 Fis1_TPR_N PF14852.6 RUS73679.1 - 0.55 10.0 34.2 84 3.0 0.2 11.2 2 1 13 16 16 16 0 Fis1 N-terminal tetratricopeptide repeat DUF948 PF06103.11 RUS73680.1 - 2.6e-10 40.4 0.0 0.0063 16.7 0.0 3.6 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF948) Collagen_mid PF15984.5 RUS73680.1 - 0.00029 20.6 0.1 0.0071 16.1 0.0 2.4 1 1 1 2 2 2 1 Bacterial collagen, middle region MtrB PF05440.12 RUS73680.1 - 0.013 15.8 0.0 48 4.5 0.0 3.4 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B MAAL_C PF07476.11 RUS73680.1 - 0.12 11.5 0.0 0.53 9.4 0.0 1.7 1 1 1 2 2 2 0 Methylaspartate ammonia-lyase C-terminus SMBP PF16785.5 RUS73680.1 - 0.37 11.0 14.8 2.4e+02 2.0 0.1 4.8 1 1 1 2 2 2 0 Small metal-binding protein Rrn6 PF10214.9 RUS73682.1 - 0.011 14.3 7.4 0.13 10.7 0.3 3.0 1 1 2 3 3 3 0 RNA polymerase I-specific transcription-initiation factor DUF2007 PF09413.10 RUS73682.1 - 0.031 14.5 0.0 95 3.3 0.0 4.2 1 1 1 4 4 4 0 Putative prokaryotic signal transducing protein STAS PF01740.21 RUS73682.1 - 0.15 11.7 0.1 7.6 6.2 0.1 3.2 1 1 0 1 1 1 0 STAS domain Mitochondr_Som1 PF11093.8 RUS73682.1 - 1.5 8.8 19.2 41 4.3 0.2 7.2 2 2 3 6 6 6 0 Mitochondrial export protein Som1 Sulfotransfer_2 PF03567.14 RUS73684.1 - 5.9e-37 127.9 0.7 8.5e-37 127.4 0.7 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS73685.1 - 7.3e-18 65.4 0.4 9.1e-18 65.1 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase family Ig_3 PF13927.6 RUS73686.1 - 3.9e-07 30.6 10.4 9.4e-06 26.1 0.1 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RUS73686.1 - 5.5e-06 26.6 0.1 0.00085 19.6 0.1 3.0 2 0 0 2 2 2 1 Immunoglobulin domain UL45 PF05473.12 RUS73686.1 - 0.0042 16.7 0.2 0.014 15.0 0.2 1.9 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Macoilin PF09726.9 RUS73686.1 - 8.2 4.9 13.3 12 4.3 13.3 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 RUS73686.1 - 9.7 4.9 16.6 17 4.1 16.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain STAG PF08514.11 RUS73687.1 - 5.3e-38 129.4 0.3 5.3e-38 129.4 0.3 1.8 2 0 0 2 2 2 1 STAG domain Tho2 PF11262.8 RUS73687.1 - 0.017 14.4 7.4 0.71 9.0 0.3 3.0 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF3807 PF12720.7 RUS73687.1 - 8.3 6.6 16.3 4.5 7.5 2.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3807) Kelch_1 PF01344.25 RUS73688.1 - 7.6e-20 70.2 14.6 3.7e-09 36.0 0.7 4.3 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 RUS73688.1 - 6.6e-16 58.0 8.5 5.4e-07 29.7 0.3 4.3 1 1 2 3 3 3 3 Kelch motif Kelch_3 PF13415.6 RUS73688.1 - 4.6e-10 39.5 3.9 0.0023 18.2 0.2 3.7 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS73688.1 - 8.6e-10 38.4 10.9 0.00038 20.4 0.1 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 RUS73688.1 - 2e-09 37.0 8.6 0.00015 21.6 0.3 3.9 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 RUS73688.1 - 9.7e-06 25.5 7.4 0.0032 17.4 1.3 3.7 3 2 0 3 3 3 2 Galactose oxidase, central domain PPP4R2 PF09184.11 RUS73689.1 - 0.0015 18.2 33.1 0.0019 17.8 33.1 1.1 1 0 0 1 1 1 1 PPP4R2 BUD22 PF09073.10 RUS73689.1 - 0.037 13.4 31.2 0.045 13.1 31.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS73689.1 - 0.048 11.9 39.4 0.056 11.7 39.4 1.0 1 0 0 1 1 1 0 Nop14-like family Arabino_trans_C PF14896.6 RUS73689.1 - 0.16 11.0 5.2 0.24 10.3 5.2 1.3 1 0 0 1 1 1 0 EmbC C-terminal domain RR_TM4-6 PF06459.12 RUS73689.1 - 0.18 11.6 28.6 0.26 11.1 28.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 RUS73689.1 - 0.23 11.9 16.7 0.3 11.6 16.7 1.2 1 0 0 1 1 1 0 AAA domain DUF4045 PF13254.6 RUS73689.1 - 0.24 11.0 19.2 0.29 10.8 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MDM1 PF15501.6 RUS73689.1 - 0.25 10.4 26.7 0.31 10.2 26.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SAPS PF04499.15 RUS73689.1 - 0.82 8.4 14.7 0.79 8.4 14.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS73689.1 - 1.6 8.0 41.2 2.1 7.7 41.2 1.2 1 0 0 1 1 1 0 SDA1 FGF-BP1 PF06473.12 RUS73689.1 - 2.6 7.8 16.8 3.4 7.5 16.8 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SID-1_RNA_chan PF13965.6 RUS73689.1 - 2.7 6.3 5.6 2.6 6.4 5.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mpp10 PF04006.12 RUS73689.1 - 2.7 6.3 42.0 4.3 5.6 42.0 1.3 1 0 0 1 1 1 0 Mpp10 protein NPR3 PF03666.13 RUS73689.1 - 3 6.5 27.2 4 6.1 27.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4050 PF13259.6 RUS73689.1 - 6.4 7.1 20.2 10 6.4 20.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Presenilin PF01080.17 RUS73689.1 - 8.6 5.0 25.9 12 4.6 25.9 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 RUS73689.1 - 8.6 6.2 20.9 9.5 6.1 20.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 RUS73689.1 - 9.8 6.1 15.0 15 5.5 15.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Band_7 PF01145.25 RUS73690.1 - 3.2e-09 37.0 0.0 8.1e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF3791 PF12668.7 RUS73690.1 - 0.095 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF4570 PF15134.6 RUS73690.1 - 0.13 12.3 2.6 0.23 11.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) RAM PF15320.6 RUS73691.1 - 0.019 15.5 3.5 0.063 13.9 3.5 1.8 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein TSC22 PF01166.18 RUS73691.1 - 0.19 12.1 2.1 5.5 7.4 0.4 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family IZUMO PF15005.6 RUS73691.1 - 0.2 12.1 4.8 0.16 12.5 2.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CLZ PF16526.5 RUS73691.1 - 0.33 11.3 7.4 9.2 6.7 0.2 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PfkB PF00294.24 RUS73692.1 - 3.4e-14 52.9 0.0 3.9e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SBF PF01758.16 RUS73693.1 - 3.8e-32 111.5 11.1 3.8e-32 111.5 11.1 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family COX14 PF14880.6 RUS73693.1 - 0.25 11.2 1.2 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3652 PF12372.8 RUS73694.1 - 5.1e-17 61.5 0.4 1.9e-16 59.7 0.4 2.1 1 0 0 1 1 1 1 Huntingtin protein region HEAT PF02985.22 RUS73694.1 - 7.1e-08 32.1 5.9 0.14 12.5 0.0 5.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 RUS73694.1 - 0.00087 19.6 0.5 2 8.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 RUS73694.1 - 0.077 13.6 0.1 5.4 7.7 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Nse4_C PF08743.10 RUS73695.1 - 4.2e-28 97.4 0.4 1.2e-27 96.0 0.1 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 RUS73695.1 - 8.1e-07 29.1 0.4 1.6e-06 28.1 0.4 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE HLH PF00010.26 RUS73697.1 - 2.4e-14 53.0 0.3 5.3e-14 51.9 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DNA_pol_phi PF04931.13 RUS73697.1 - 2.7 6.0 47.4 4.3 5.3 47.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RUS73697.1 - 7.4 5.9 21.8 17 4.7 21.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HLH PF00010.26 RUS73698.1 - 2e-15 56.5 1.6 3e-15 55.9 1.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Claudin_2 PF13903.6 RUS73699.1 - 0.21 11.3 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Menin PF05053.13 RUS73700.1 - 0.0049 15.3 2.6 0.0052 15.2 2.6 1.2 1 0 0 1 1 1 1 Menin DUF1644 PF07800.12 RUS73700.1 - 0.011 15.8 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) V-set PF07686.17 RUS73700.1 - 0.023 14.8 9.3 0.79 9.9 0.2 2.9 1 1 1 2 2 2 0 Immunoglobulin V-set domain Inp1 PF12634.7 RUS73700.1 - 0.06 13.4 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 Inheritance of peroxisomes protein 1 DUF4820 PF16091.5 RUS73700.1 - 0.096 12.0 2.0 0.16 11.3 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Macoilin PF09726.9 RUS73700.1 - 0.67 8.4 5.6 0.77 8.2 5.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 RUS73700.1 - 1.7 9.6 4.2 0.63 11.0 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Minor_tail_Z PF06763.11 RUS73701.1 - 0.00049 19.9 1.3 1.6 8.5 1.3 3.2 1 1 0 1 1 1 1 Prophage minor tail protein Z (GPZ) GerPC PF10737.9 RUS73701.1 - 0.037 14.1 14.8 0.053 13.6 14.8 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Tipalpha PF16753.5 RUS73701.1 - 0.053 13.3 9.5 1.1e+02 2.5 9.5 3.0 1 1 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter YpjP PF14005.6 RUS73701.1 - 0.16 12.0 17.0 2.9e+02 1.5 17.0 2.5 1 1 0 1 1 1 0 YpjP-like protein Cellsynth_D PF03500.13 RUS73701.1 - 0.61 10.0 7.6 8.5 6.2 0.7 3.0 1 1 1 2 2 2 0 Cellulose synthase subunit D Peptidase_S46 PF10459.9 RUS73701.1 - 1 7.9 5.1 4.3 5.9 5.1 1.8 1 1 0 1 1 1 0 Peptidase S46 Trypan_PARP PF05887.11 RUS73701.1 - 9.7 6.2 11.5 86 3.1 11.5 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) JHY PF15261.6 RUS73703.1 - 7.7e-24 84.9 4.8 7.7e-24 84.9 4.8 2.4 2 1 0 2 2 2 1 Jhy protein SMAP PF15477.6 RUS73703.1 - 4.3 8.4 5.9 1.1 10.3 1.1 2.4 3 0 0 3 3 3 0 Small acidic protein family DUF5327 PF17261.2 RUS73703.1 - 5.7 7.7 7.5 4.2 8.2 1.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) HalX PF08663.10 RUS73704.1 - 1.8 8.9 9.7 12 6.3 0.7 2.9 2 0 0 2 2 2 0 HalX domain GP67 PF17634.2 RUS73706.1 - 0.0096 16.3 4.7 0.019 15.3 4.7 1.4 1 0 0 1 1 1 1 Gene product 67 PBP1_TM PF14812.6 RUS73706.1 - 0.017 15.5 2.5 0.077 13.4 2.5 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3c_N PF05470.12 RUS73706.1 - 0.32 9.3 1.5 0.54 8.5 1.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 RUS73706.1 - 1.4 8.2 5.3 3 7.1 5.3 1.5 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RUS73706.1 - 2.6 8.5 9.9 7.8 7.0 9.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EccE PF11203.8 RUS73707.1 - 3.8 7.9 7.5 0.43 10.9 1.2 2.3 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PDZ_6 PF17820.1 RUS73708.1 - 1.4e-33 114.5 1.8 8.1e-12 44.8 0.2 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 RUS73708.1 - 2.6e-30 104.6 0.0 1.6e-09 38.0 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 RUS73708.1 - 8.8e-19 67.6 0.0 1.2e-05 25.5 0.0 3.4 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 RUS73708.1 - 0.0018 18.2 0.1 5.8 7.0 0.0 3.2 3 0 0 3 3 3 2 Tricorn protease PDZ domain zf-C2H2_jaz PF12171.8 RUS73708.1 - 0.23 11.8 1.2 66 4.0 0.1 3.2 1 1 3 4 4 4 0 Zinc-finger double-stranded RNA-binding DHHC PF01529.20 RUS73709.1 - 1.5e-35 122.2 7.8 1.5e-35 122.2 7.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Comm PF15957.5 RUS73709.1 - 0.054 13.8 2.2 0.056 13.8 0.0 2.2 2 0 0 2 2 2 0 Commissureless Claudin_2 PF13903.6 RUS73715.1 - 4.4e-13 49.4 0.2 5.3e-13 49.2 0.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS73715.1 - 9.6e-10 38.6 0.1 1.2e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 RUS73715.1 - 4.1e-05 23.5 0.2 4.6e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein BPD_transp_2 PF02653.16 RUS73715.1 - 0.0078 15.4 0.3 0.0098 15.1 0.3 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component YtpI PF14007.6 RUS73715.1 - 0.012 15.7 1.9 3.7 7.8 0.1 2.3 2 0 0 2 2 2 0 YtpI-like protein DUF2569 PF10754.9 RUS73715.1 - 0.015 15.8 7.0 0.19 12.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2207 PF09972.9 RUS73715.1 - 0.015 14.1 0.5 0.023 13.5 0.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.11 RUS73715.1 - 0.019 14.7 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein SUR7 PF06687.12 RUS73715.1 - 0.026 14.1 3.7 0.044 13.4 3.7 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF5305 PF17231.2 RUS73715.1 - 0.041 13.3 1.0 8.6 5.7 0.1 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5305) OAD_gamma PF04277.13 RUS73715.1 - 0.067 13.8 0.8 0.86 10.2 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF202 PF02656.15 RUS73715.1 - 0.081 13.4 2.1 0.47 10.9 2.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MARVEL PF01284.23 RUS73715.1 - 0.13 12.3 5.5 0.31 11.1 4.6 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF4179 PF13786.6 RUS73715.1 - 0.24 11.9 1.3 0.34 11.4 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) Saf_2TM PF18303.1 RUS73715.1 - 0.27 10.8 3.0 4.5 6.9 0.3 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Glucos_trans_II PF14264.6 RUS73715.1 - 0.31 10.4 8.4 0.76 9.1 8.5 1.5 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF373 PF04123.13 RUS73715.1 - 0.47 9.9 3.5 0.74 9.2 3.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF996 PF06195.13 RUS73715.1 - 0.54 10.5 8.0 0.8 10.0 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF996) Tetraspanin PF00335.20 RUS73715.1 - 0.83 9.3 4.3 5 6.8 0.2 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF1218 PF06749.12 RUS73715.1 - 0.84 10.2 6.6 2.8 8.5 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) FixQ PF05545.11 RUS73715.1 - 0.89 9.6 8.2 0.27 11.2 2.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MFS_1 PF07690.16 RUS73715.1 - 1 8.2 6.8 3.5 6.4 6.9 1.6 1 1 1 2 2 2 0 Major Facilitator Superfamily Wzy_C PF04932.15 RUS73715.1 - 1.2 8.8 5.6 4.4 6.9 5.6 1.8 1 1 0 1 1 1 0 O-Antigen ligase DUF2975 PF11188.8 RUS73715.1 - 1.7 8.5 10.6 0.21 11.5 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DHHC PF01529.20 RUS73715.1 - 1.8 8.7 6.1 5.1 7.2 1.6 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF3671 PF12420.8 RUS73715.1 - 2.2 8.4 5.6 35 4.5 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function E1-E2_ATPase PF00122.20 RUS73715.1 - 3.7 7.0 7.0 12 5.4 0.4 2.1 1 1 1 2 2 2 0 E1-E2 ATPase DUF2157 PF09925.9 RUS73715.1 - 9.2 6.0 7.5 1.3 8.8 2.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Claudin_2 PF13903.6 RUS73716.1 - 4.3e-15 56.0 2.9 6.6e-15 55.4 2.9 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3796 PF12676.7 RUS73716.1 - 0.034 14.6 0.3 0.034 14.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Pentapeptide_3 PF13576.6 RUS73717.1 - 0.65 10.2 3.8 1e+02 3.2 0.1 3.8 1 1 5 6 6 6 0 Pentapeptide repeats (9 copies) Intein_splicing PF14890.6 RUS73717.1 - 0.68 9.9 23.8 14 5.6 1.9 6.2 1 1 5 7 7 7 0 Intein splicing domain dDENN PF03455.19 RUS73717.1 - 0.72 9.9 5.5 99 3.0 0.7 4.8 1 1 4 5 5 5 0 dDENN domain JTB PF05439.12 RUS73717.1 - 1.2 9.2 35.6 3.2 7.9 4.3 4.2 1 1 3 4 4 4 0 Jumping translocation breakpoint protein (JTB) CENP-X PF09415.10 RUS73718.1 - 3e-16 59.5 0.5 4.8e-16 58.8 0.5 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Peptidase_M16 PF00675.20 RUS73720.1 - 1.1e-19 70.9 0.0 2.7e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RUS73720.1 - 3.5e-17 63.0 0.0 1.5e-16 61.0 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain DUF1107 PF06526.12 RUS73720.1 - 0.0096 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) DUF4175 PF13779.6 RUS73720.1 - 0.13 10.2 0.2 0.18 9.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EF-hand_7 PF13499.6 RUS73721.1 - 8.1e-15 55.0 3.6 8.1e-15 55.0 3.6 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS73721.1 - 1.9e-10 39.5 9.8 7.9e-06 25.1 4.3 2.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS73721.1 - 4e-09 35.7 6.9 0.00064 19.4 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS73721.1 - 5.7e-09 35.7 3.6 1.8e-08 34.1 1.9 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS73721.1 - 2.4e-07 30.0 3.6 2.2e-06 26.9 2.6 2.4 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 RUS73721.1 - 0.00016 22.0 0.6 0.0002 21.6 0.6 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 RUS73721.1 - 0.0005 20.0 0.6 0.00062 19.7 0.6 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SAM_LFY PF01698.16 RUS73721.1 - 0.037 14.0 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain SPARC_Ca_bdg PF10591.9 RUS73721.1 - 0.038 14.3 0.9 0.1 13.0 0.9 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region WEMBL PF05701.11 RUS73721.1 - 0.049 12.3 0.1 0.056 12.1 0.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SUD-M PF11633.8 RUS73721.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain FAS_N PF17828.1 RUS73721.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta RhoGAP PF00620.27 RUS73722.1 - 8.1e-41 139.4 0.8 5.1e-40 136.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 RUS73722.1 - 7e-16 58.7 0.2 1.3e-15 57.8 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS73722.1 - 9.4e-05 22.8 5.5 0.0001 22.7 1.3 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Lebercilin PF15619.6 RUS73722.1 - 0.00084 19.0 11.2 0.0016 18.1 11.2 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 RUS73722.1 - 0.064 13.7 4.4 0.74 10.3 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 MPS2 PF17060.5 RUS73722.1 - 0.1 11.8 5.2 0.22 10.7 5.2 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 LLC1 PF14945.6 RUS73722.1 - 0.18 12.4 0.7 28 5.3 0.3 2.5 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein PH_16 PF17838.1 RUS73722.1 - 0.3 10.9 2.6 0.96 9.3 0.0 2.5 3 0 0 3 3 3 0 PH domain FapA PF03961.13 RUS73722.1 - 0.42 9.2 4.2 0.62 8.6 4.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MatP_C PF17414.2 RUS73722.1 - 0.57 10.4 4.1 2.7 8.2 2.1 2.8 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain DUF4407 PF14362.6 RUS73722.1 - 0.6 9.4 4.6 1 8.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 RUS73722.1 - 1.2 9.6 5.5 3 8.3 4.6 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 RUS73722.1 - 1.4 8.5 6.0 2.5 7.6 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 RUS73722.1 - 1.4 9.1 14.0 2.5 8.3 14.0 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 THOC7 PF05615.13 RUS73722.1 - 4.2 7.6 12.9 9.4 6.5 12.9 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 V_ATPase_I PF01496.19 RUS73722.1 - 6.2 4.6 7.3 8.7 4.1 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 RUS73722.1 - 8.2 6.8 12.5 0.67 10.3 5.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Pkinase PF00069.25 RUS73723.1 - 2.4e-59 200.9 0.0 3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73723.1 - 1.6e-26 93.1 0.1 2.3e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RUS73723.1 - 2.8e-05 23.8 0.6 5.1e-05 23.0 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 RUS73723.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS73723.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS73723.1 - 0.00077 18.9 1.0 0.0052 16.2 1.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS73723.1 - 0.046 13.3 0.1 0.1 12.2 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NtA PF03146.15 RUS73725.1 - 0.22 11.4 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Agrin NtA domain Fmp27_SW PF10305.9 RUS73726.1 - 0.059 14.1 2.1 0.2 12.4 0.7 2.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TPR_2 PF07719.17 RUS73727.1 - 1.2e-10 40.7 5.4 0.0027 17.7 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS73727.1 - 1.2e-10 41.7 1.8 0.00018 21.9 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS73727.1 - 4.9e-10 39.4 0.4 0.41 11.6 0.0 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS73727.1 - 6.6e-07 28.9 5.2 0.064 13.1 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS73727.1 - 4.9e-05 23.9 0.9 0.38 11.4 0.0 3.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS73727.1 - 9.1e-05 22.4 6.0 0.096 12.9 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF5588 PF17826.1 RUS73727.1 - 0.0011 18.0 0.2 0.0017 17.3 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TPR_9 PF13371.6 RUS73727.1 - 0.0066 16.6 0.4 3.9 7.7 0.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 RUS73727.1 - 0.0077 15.3 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 RUS73727.1 - 0.015 14.2 5.6 0.031 13.2 2.9 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_C50 PF03568.17 RUS73727.1 - 0.018 14.2 0.5 0.022 13.9 0.5 1.1 1 0 0 1 1 1 0 Peptidase family C50 Sucrose_synth PF00862.19 RUS73727.1 - 0.019 13.3 0.1 0.025 12.9 0.1 1.1 1 0 0 1 1 1 0 Sucrose synthase ANAPC3 PF12895.7 RUS73727.1 - 0.21 11.8 3.4 0.2 11.9 0.9 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 RUS73727.1 - 0.4 11.1 4.7 0.57 10.6 0.3 2.4 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation TPR_12 PF13424.6 RUS73727.1 - 0.97 9.8 6.1 2.8 8.3 1.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS73727.1 - 1.7 8.4 8.3 8.1 6.2 0.1 4.0 4 0 0 4 4 4 0 TPR repeat Ax_dynein_light PF10211.9 RUS73728.1 - 9e-96 319.2 14.2 1.1e-95 319.0 14.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 RUS73728.1 - 1.4e-05 24.1 9.3 1.4e-05 24.1 9.3 1.5 2 0 0 2 2 2 1 RIB43A Mei5 PF10376.9 RUS73728.1 - 0.0012 18.8 6.4 0.0019 18.1 6.4 1.4 1 0 0 1 1 1 1 Double-strand recombination repair protein Syntaxin-6_N PF09177.11 RUS73728.1 - 0.0061 17.1 7.6 0.0061 17.1 7.6 1.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal BshC PF10079.9 RUS73728.1 - 0.0073 15.1 5.6 0.011 14.5 5.6 1.2 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Jnk-SapK_ap_N PF09744.9 RUS73728.1 - 0.0099 16.1 15.4 0.013 15.7 11.1 2.3 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 ADIP PF11559.8 RUS73728.1 - 0.016 15.3 14.3 0.016 15.3 14.3 1.5 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.18 RUS73728.1 - 0.033 14.4 4.6 0.3 11.3 1.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper UPF0242 PF06785.11 RUS73728.1 - 0.054 13.6 10.8 0.031 14.4 8.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TSNAXIP1_N PF15739.5 RUS73728.1 - 0.07 13.5 15.1 0.21 12.0 3.4 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus APG6_N PF17675.1 RUS73728.1 - 0.085 13.4 22.3 0.28 11.7 22.2 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 RUS73728.1 - 0.14 11.4 12.0 0.022 14.0 8.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 RUS73728.1 - 0.19 10.3 6.4 0.25 9.9 6.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 RUS73728.1 - 0.25 10.2 11.9 0.53 9.1 11.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 RUS73728.1 - 0.35 10.7 14.9 0.18 11.6 12.8 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 RUS73728.1 - 0.68 10.7 9.0 0.59 10.9 7.1 1.8 2 0 0 2 2 1 0 Occludin homology domain DUF16 PF01519.16 RUS73728.1 - 0.77 10.3 7.9 1.9 9.0 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 RUS73728.1 - 0.78 10.2 6.7 6.9 7.2 2.5 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF5320 PF17253.2 RUS73728.1 - 1 10.5 9.6 7.8 7.6 2.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Spc24 PF08286.11 RUS73728.1 - 1.7 9.0 13.6 1.6 9.0 11.2 2.2 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 RUS73728.1 - 1.9 6.3 6.3 2.6 5.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.6 RUS73728.1 - 2.9 8.0 7.3 5 7.2 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Shugoshin_N PF07558.11 RUS73728.1 - 3 7.8 8.1 6.7 6.7 0.4 3.0 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Mto2_bdg PF12808.7 RUS73728.1 - 4.9 7.5 18.1 1.8 8.9 1.4 3.7 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PRKG1_interact PF15898.5 RUS73728.1 - 5 8.1 17.4 3.6 8.6 14.4 2.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 RUS73728.1 - 5.2 6.2 6.3 8.1 5.6 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4164 PF13747.6 RUS73728.1 - 6.8 7.0 13.7 9.3 6.6 7.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF3958 PF13125.6 RUS73728.1 - 9.9 6.4 19.3 0.076 13.2 3.5 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3958) PHD PF00628.29 RUS73729.1 - 1e-05 25.3 11.3 2.3e-05 24.2 11.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-C2H2 PF00096.26 RUS73729.1 - 0.025 15.0 2.6 0.025 15.0 2.6 2.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Tudor-knot PF11717.8 RUS73730.1 - 1.3e-07 31.4 2.1 1.1e-06 28.4 0.9 2.5 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 RUS73730.1 - 2.1e-07 30.5 0.0 5.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 RUS73730.1 - 1.5e-06 28.0 0.0 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain MBT PF02820.18 RUS73730.1 - 3.4e-05 24.1 0.1 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 mbt repeat DUF4537 PF15057.6 RUS73730.1 - 0.00072 19.6 0.1 0.0048 16.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 RUS73730.1 - 0.003 17.3 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain SAWADEE PF16719.5 RUS73730.1 - 0.012 15.7 0.3 0.024 14.6 0.1 1.6 2 0 0 2 2 2 0 SAWADEE domain TUDOR PF00567.24 RUS73730.1 - 0.044 13.8 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Tudor domain PWWP PF00855.17 RUS73730.1 - 0.088 13.2 0.4 15 6.1 0.0 2.9 2 1 0 2 2 2 0 PWWP domain Agenet PF05641.12 RUS73730.1 - 0.11 13.0 0.2 2.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Agenet domain C2 PF00168.30 RUS73733.1 - 3.7e-38 130.0 0.0 4e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain PDZ_6 PF17820.1 RUS73733.1 - 6.7e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS73733.1 - 3.4e-08 33.7 0.1 7.6e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF2968 PF11180.8 RUS73733.1 - 0.17 11.5 1.7 0.37 10.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) C2-set PF05790.15 RUS73734.1 - 0.035 14.3 0.6 0.078 13.2 0.6 1.6 1 0 0 1 1 1 0 Immunoglobulin C2-set domain DUF572 PF04502.13 RUS73734.1 - 1.2 8.7 9.5 1.6 8.3 9.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) ThiF PF00899.21 RUS73735.1 - 3.6e-114 380.2 0.0 1.4e-73 247.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RUS73735.1 - 1.2e-92 310.5 0.5 1.2e-92 310.5 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 RUS73735.1 - 7.1e-38 129.2 0.2 1.6e-37 128.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 RUS73735.1 - 1.5e-32 111.6 0.3 3.3e-32 110.5 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 RUS73735.1 - 3.4e-27 94.4 0.4 1.5e-26 92.4 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 RUS73735.1 - 0.11 12.6 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase STI1 PF17830.1 RUS73735.1 - 0.16 11.9 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 STI1 domain IBR PF01485.21 RUS73736.1 - 7.5e-17 61.3 53.0 7.8e-12 45.3 8.0 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 RUS73736.1 - 0.00032 20.6 9.3 0.00032 20.6 9.3 4.0 2 1 2 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS73736.1 - 0.0031 17.8 9.8 0.0031 17.8 9.8 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS73736.1 - 0.0037 17.1 8.1 0.0037 17.1 8.1 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS73736.1 - 0.0096 15.9 6.6 0.0096 15.9 6.6 3.6 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS73736.1 - 0.015 15.2 6.5 0.015 15.2 6.5 4.4 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 DUF572 PF04502.13 RUS73737.1 - 1.2e-94 317.7 11.3 1.3e-94 317.5 11.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) EF-1_beta_acid PF10587.9 RUS73737.1 - 0.0068 16.8 4.1 0.076 13.5 4.1 2.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region zf-FCS PF06467.14 RUS73737.1 - 0.13 12.2 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif B-block_TFIIIC PF04182.12 RUS73738.1 - 1.8e-06 28.0 0.1 9.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC DUF5508 PF17621.2 RUS73738.1 - 0.077 12.1 1.5 0.13 11.4 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5508) ARA70 PF12489.8 RUS73738.1 - 0.13 12.4 3.8 0.33 11.1 3.8 1.6 1 0 0 1 1 1 0 Nuclear coactivator Mif2_N PF15624.6 RUS73738.1 - 9.2 7.0 9.7 0.25 12.0 2.1 2.2 3 0 0 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal LIN37 PF15306.6 RUS73739.1 - 0.31 11.3 4.1 0.084 13.1 1.0 1.6 2 0 0 2 2 2 0 LIN37 Ribosomal_L30_N PF08079.12 RUS73739.1 - 0.36 11.1 5.5 0.07 13.4 1.6 1.8 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain zf-CCCH PF00642.24 RUS73740.1 - 4.4e-07 29.6 0.9 8.2e-07 28.8 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS73740.1 - 2.3e-05 24.3 3.1 4.5e-05 23.4 3.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 RUS73740.1 - 4.6e-05 23.1 1.1 8.8e-05 22.2 1.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 RUS73740.1 - 0.0012 18.8 1.3 0.003 17.6 1.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.6 RUS73740.1 - 0.15 12.5 2.4 0.29 11.7 2.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Macoilin PF09726.9 RUS73740.1 - 3.3 6.1 36.6 5.7 5.4 36.6 1.3 1 0 0 1 1 1 0 Macoilin family HSP70 PF00012.20 RUS73741.1 - 3e-266 884.4 12.8 3.4e-266 884.2 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS73741.1 - 7.4e-16 57.9 0.8 1.6e-14 53.5 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RUS73741.1 - 0.0032 17.9 6.6 0.3 11.5 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 RUS73741.1 - 0.025 13.6 3.2 0.18 10.8 0.8 2.7 1 1 1 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 RUS73741.1 - 0.029 14.1 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 RUS73741.1 - 0.038 13.3 0.1 0.038 13.3 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Zincin_2 PF10103.9 RUS73741.1 - 0.15 11.3 0.0 0.48 9.6 0.0 1.7 2 0 0 2 2 2 0 Zincin-like metallopeptidase AAA_23 PF13476.6 RUS73741.1 - 2.1 8.8 13.4 12 6.3 8.2 2.4 2 0 0 2 2 2 0 AAA domain 7TM_GPCR_Srw PF10324.9 RUS73742.1 - 8.4e-07 28.6 10.6 3.4e-05 23.3 10.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Laminin_N PF00055.17 RUS73743.1 - 3.8e-82 275.4 0.3 3.8e-82 275.4 0.3 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 RUS73743.1 - 3.4e-32 110.3 79.9 5.7e-13 48.8 13.3 5.8 6 0 0 6 6 6 4 Laminin EGF domain Laminin_B PF00052.18 RUS73743.1 - 1.5e-18 67.0 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Laminin B (Domain IV) zf-CHY PF05495.12 RUS73744.1 - 3.6e-11 43.4 14.6 3.6e-11 43.4 14.6 4.9 5 0 0 5 5 5 1 CHY zinc finger zf-CCCH PF00642.24 RUS73744.1 - 1.4e-10 40.8 31.9 0.00077 19.3 2.3 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RUS73744.1 - 9.7e-10 38.0 41.3 1.4e-06 27.9 3.1 4.3 5 0 0 5 5 4 3 CCCH-type zinc finger Torus PF16131.5 RUS73744.1 - 7.9e-09 36.2 3.5 9.5e-06 26.3 0.4 4.1 3 1 1 4 4 3 2 Torus domain zf_CCCH_4 PF18345.1 RUS73744.1 - 6.7e-07 29.2 47.8 9.7e-05 22.3 5.6 4.5 5 0 0 5 5 5 3 Zinc finger domain RWD PF05773.22 RUS73744.1 - 0.0092 16.3 0.1 0.025 14.9 0.1 1.8 1 0 0 1 1 1 1 RWD domain zf-CCCH_3 PF15663.5 RUS73744.1 - 0.019 15.2 9.0 0.027 14.7 0.2 3.4 2 1 1 3 3 3 0 Zinc-finger containing family RRN3 PF05327.11 RUS73744.1 - 0.32 9.5 1.9 0.47 8.9 1.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-CCCH_2 PF14608.6 RUS73744.1 - 0.54 10.8 29.1 0.48 11.0 7.7 4.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DNA_pol_phi PF04931.13 RUS73744.1 - 0.87 7.6 12.8 1.3 7.1 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 RUS73744.1 - 2.6 7.0 5.4 4.4 6.3 5.4 1.3 1 0 0 1 1 1 0 Pes-10 Thioredoxin PF00085.20 RUS73745.1 - 1.5e-92 304.3 0.2 5.6e-31 106.6 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 RUS73745.1 - 4.4e-21 75.6 8.1 2.1e-16 60.4 3.6 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RUS73745.1 - 9.4e-14 51.8 2.6 0.0024 18.3 0.0 5.2 3 3 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 RUS73745.1 - 2.7e-13 49.9 0.0 0.004 16.6 0.0 3.6 3 1 1 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 RUS73745.1 - 3.6e-13 49.5 0.0 0.008 16.3 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_8 PF13905.6 RUS73745.1 - 3.9e-13 49.5 0.7 0.058 13.7 0.0 6.6 4 2 2 6 6 6 3 Thioredoxin-like Calsequestrin PF01216.17 RUS73745.1 - 5e-12 45.6 7.3 1.5e-08 34.1 5.2 2.9 2 1 1 3 3 3 2 Calsequestrin AhpC-TSA PF00578.21 RUS73745.1 - 1.1e-09 38.2 3.5 0.032 14.2 0.0 4.8 3 1 1 5 5 5 3 AhpC/TSA family Redoxin PF08534.10 RUS73745.1 - 1.2e-05 25.0 0.5 0.82 9.4 0.0 3.8 4 0 0 4 4 4 2 Redoxin HyaE PF07449.11 RUS73745.1 - 0.002 18.0 0.0 2.3 8.2 0.0 3.3 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF3000 PF11452.8 RUS73745.1 - 0.0071 15.9 0.0 0.21 11.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3000) Thioredoxin_3 PF13192.6 RUS73745.1 - 0.013 15.5 0.0 4.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_9 PF14595.6 RUS73745.1 - 0.014 15.2 0.2 13 5.6 0.0 3.8 4 0 0 4 4 4 0 Thioredoxin LAT PF15234.6 RUS73745.1 - 0.079 12.7 0.1 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Linker for activation of T-cells DUF836 PF05768.14 RUS73745.1 - 0.083 13.3 0.0 7.3 7.1 0.1 3.7 3 1 0 3 3 3 0 Glutaredoxin-like domain (DUF836) RBFA PF02033.18 RUS73745.1 - 0.16 12.4 0.0 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ribosome-binding factor A UCH_1 PF13423.6 RUS73745.1 - 0.22 11.1 0.0 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L40e PF01020.17 RUS73745.1 - 1.7 8.6 5.0 22 5.1 0.4 3.6 3 1 1 4 4 4 0 Ribosomal L40e family Mu-like_Com PF10122.9 RUS73745.1 - 2.3 7.7 3.8 47 3.5 0.1 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com Sulfotransfer_3 PF13469.6 RUS73746.1 - 0.0012 19.3 0.5 0.0039 17.6 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase family Galactosyl_T PF01762.21 RUS73748.1 - 1.7e-28 99.8 0.7 1.4e-21 77.2 0.2 2.2 2 0 0 2 2 2 2 Galactosyltransferase Insulin PF00049.18 RUS73749.1 - 0.095 13.7 0.0 0.25 12.4 0.0 1.7 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family BH4 PF02180.17 RUS73750.1 - 2.2 8.2 32.4 1.1e+02 2.8 0.1 10.2 10 0 0 10 10 10 0 Bcl-2 homology region 4 Ig_3 PF13927.6 RUS73751.1 - 3.5e-11 43.5 0.0 5.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS73751.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_2 PF07648.15 RUS73751.1 - 2e-07 31.0 0.8 2e-07 31.0 0.8 2.9 2 1 1 3 3 3 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.18 RUS73751.1 - 1.3e-06 28.9 22.2 1.3e-06 28.9 22.2 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein ig PF00047.25 RUS73751.1 - 5.2e-06 26.5 0.1 1.7e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS73751.1 - 7.1e-05 23.1 0.1 0.00021 21.5 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 RUS73751.1 - 0.00013 21.9 2.9 0.00013 21.9 2.9 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 RUS73751.1 - 0.031 14.4 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin V-set domain adh_short PF00106.25 RUS73752.1 - 1.9e-36 125.4 0.1 2.3e-35 121.8 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS73752.1 - 1.2e-26 93.7 0.0 3e-25 89.1 0.0 2.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS73752.1 - 6.6e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS73752.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family BSMAP PF12280.8 RUS73753.1 - 7.7e-18 65.4 0.8 1.2e-16 61.5 0.1 2.0 2 0 0 2 2 2 1 Brain specific membrane anchored protein DUF1939 PF09154.10 RUS73753.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) GRP PF07172.11 RUS73754.1 - 0.9 10.3 19.0 2 9.1 19.0 1.6 1 0 0 1 1 1 0 Glycine rich protein family Keratin_2_head PF16208.5 RUS73754.1 - 2 8.6 17.3 2.9 8.0 17.3 1.2 1 0 0 1 1 1 0 Keratin type II head PDZ_6 PF17820.1 RUS73755.1 - 2.4e-07 30.5 0.5 5.9e-05 22.8 0.1 3.4 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 RUS73755.1 - 5.5e-06 26.6 0.6 4.7e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 RUS73755.1 - 0.063 13.6 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 PDZ domain zf-C2H2_4 PF13894.6 RUS73757.1 - 7.5e-16 57.5 54.0 0.016 16.0 0.2 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS73757.1 - 9.3e-16 57.3 56.2 2.6e-05 24.4 2.2 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS73757.1 - 1.8e-06 28.1 54.7 0.093 13.2 2.1 9.7 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS73757.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 7.2 8 0 0 8 8 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 RUS73757.1 - 0.0022 18.2 39.1 0.005 17.1 4.2 5.8 6 0 0 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RUS73757.1 - 0.0049 16.6 1.6 0.0049 16.6 1.6 7.5 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 RUS73757.1 - 0.04 14.1 14.2 1.1 9.3 0.9 4.5 3 2 0 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 RUS73757.1 - 0.065 13.6 0.2 0.065 13.6 0.2 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS73757.1 - 0.25 11.7 25.7 1.9 8.9 0.0 7.5 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 RUS73757.1 - 0.78 10.3 13.8 4 8.0 0.0 5.6 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 RUS73757.1 - 1.2 9.0 13.4 1.7 8.5 0.2 5.2 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 RUS73757.1 - 1.4 9.6 22.6 1.2 9.8 1.8 5.7 5 1 1 6 6 6 0 FOXP coiled-coil domain GAGA PF09237.11 RUS73757.1 - 5.8 6.8 10.6 14 5.5 0.0 4.9 6 0 0 6 6 6 0 GAGA factor Vps8 PF12816.7 RUS73758.1 - 0.00014 21.5 0.0 0.82 9.1 0.0 3.2 1 1 1 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Toxin_7 PF05980.12 RUS73758.1 - 0.00053 20.2 7.7 16 5.9 0.0 4.5 5 0 0 5 5 5 1 Toxin 7 DOG1 PF14144.6 RUS73758.1 - 0.001 19.2 4.3 29 5.0 0.1 4.2 1 1 3 4 4 4 0 Seed dormancy control CsgG PF03783.14 RUS73758.1 - 0.0017 17.7 0.0 33 3.7 0.0 3.8 1 1 3 4 4 4 0 Curli production assembly/transport component CsgG DUF1610 PF07754.11 RUS73758.1 - 0.0095 15.9 0.0 1.5e+02 2.5 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1610) dCMP_cyt_deam_2 PF08211.12 RUS73758.1 - 0.015 15.5 0.1 1.8 8.8 0.1 2.1 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Dam PF05869.11 RUS73758.1 - 0.016 14.8 2.6 0.96 9.0 1.2 3.7 1 1 1 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) Sorb PF02208.16 RUS73758.1 - 0.17 11.8 0.1 2.7e+02 1.5 0.0 3.7 4 0 0 4 4 4 0 Sorbin homologous domain Bowman-Birk_leg PF00228.20 RUS73758.1 - 4.1 7.9 10.2 1.4e+02 3.0 0.1 4.2 4 0 0 4 4 4 0 Bowman-Birk serine protease inhibitor family Ribosomal_S6e PF01092.19 RUS73759.1 - 0.0038 17.2 0.0 4.8 7.2 0.0 2.9 1 1 0 2 2 2 2 Ribosomal protein S6e Glyco_hydro_65C PF03633.15 RUS73759.1 - 0.015 15.2 11.7 0.94 9.4 0.2 4.5 1 1 3 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain DUF5323 PF17257.2 RUS73759.1 - 0.52 10.2 6.8 14 5.7 0.0 4.8 2 2 3 6 6 6 0 Family of unknown function (DUF5323) DUF2116 PF09889.9 RUS73760.1 - 9.9 6.2 19.0 31 4.6 0.1 5.4 1 1 7 8 8 8 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1674 PF07896.12 RUS73761.1 - 5.8e-20 71.5 5.1 5.8e-20 71.5 5.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1674) Mastoparan_2 PF08251.11 RUS73762.1 - 0.0018 18.2 21.8 2.4e+02 2.4 0.0 10.5 11 1 1 12 12 12 0 Mastoparan peptide SASP PF00269.20 RUS73762.1 - 0.003 17.5 3.1 26 4.9 0.2 5.4 1 1 3 4 4 4 1 Small, acid-soluble spore proteins, alpha/beta type gag-asp_proteas PF13975.6 RUS73762.1 - 0.044 14.4 5.5 3.5 8.2 0.7 2.9 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Nse4-Nse3_bdg PF15412.6 RUS73762.1 - 0.45 10.7 10.0 76 3.5 0.1 5.3 1 1 10 11 11 11 0 Binding domain of Nse4/EID3 to Nse3-MAGE DUF565 PF04483.12 RUS73762.1 - 0.65 10.6 17.5 63 4.2 0.3 6.4 1 1 3 4 4 4 0 Protein of unknown function (DUF565) DUF4214 PF13946.6 RUS73762.1 - 1 9.5 4.1 1.3e+02 2.7 0.1 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4214) PPC PF04151.15 RUS73764.1 - 5.5 8.2 5.6 11 7.2 0.1 2.9 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain DUF3778 PF12620.8 RUS73765.1 - 0.21 11.2 20.7 21 4.8 0.2 7.0 4 3 4 8 8 8 0 Protein of unknown function (DUF3778) Phage_T4_Gp30_7 PF06919.11 RUS73765.1 - 0.74 10.0 10.6 15 5.7 0.4 4.4 1 1 3 4 4 4 0 Phage Gp30.7 protein Pet191_N PF10203.9 RUS73765.1 - 4.9 7.5 7.2 9.2 6.7 0.0 4.2 2 2 1 4 4 4 0 Cytochrome c oxidase assembly protein PET191 DUF963 PF06131.11 RUS73766.1 - 0.33 10.4 9.1 0.3 10.5 3.4 2.8 3 0 0 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF4041 PF13250.6 RUS73767.1 - 1.1e-05 25.3 8.6 1.2 9.1 0.2 4.3 1 1 4 5 5 5 5 Domain of unknown function (DUF4041) TetR_C_36 PF18598.1 RUS73767.1 - 0.00046 20.1 0.0 54 3.8 0.0 5.5 1 1 7 8 8 8 0 Tetracyclin repressor-like, C-terminal domain DUF1859 PF08948.10 RUS73767.1 - 0.0016 18.4 7.3 5.7 6.9 0.3 3.8 1 1 4 5 5 5 4 Domain of unknown function (DUF1859) SF-assemblin PF06705.11 RUS73767.1 - 0.035 13.4 0.1 4.1 6.7 0.0 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF4498 PF14926.6 RUS73767.1 - 0.038 13.3 6.0 4.9 6.4 0.3 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4498) cNMP_binding PF00027.29 RUS73768.1 - 1.3e-20 73.2 0.0 2.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RIIa PF02197.17 RUS73768.1 - 2.2e-09 36.8 0.0 3.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit HLH PF00010.26 RUS73769.1 - 0.0072 16.3 0.1 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cadherin PF00028.17 RUS73770.1 - 0 1344.7 57.9 8.4e-21 74.2 0.5 29.1 29 0 0 29 29 29 28 Cadherin domain Cadherin_2 PF08266.12 RUS73770.1 - 3e-22 78.2 8.4 0.29 11.0 0.0 18.2 22 0 0 22 22 22 5 Cadherin-like RET_CLD1 PF17756.1 RUS73770.1 - 1.1e-13 51.5 0.0 0.71 10.2 0.0 10.9 12 1 0 12 12 12 2 RET Cadherin like domain 1 Cadherin_3 PF16184.5 RUS73770.1 - 1.6e-13 50.6 45.1 1.4 9.0 0.1 17.9 19 0 0 19 19 19 8 Cadherin-like Cadherin_pro PF08758.11 RUS73770.1 - 3.8e-13 49.4 1.6 0.0014 18.7 0.0 10.1 10 0 0 10 10 10 2 Cadherin prodomain like PepSY PF03413.19 RUS73770.1 - 4.5e-05 23.9 11.6 2.9 8.5 0.0 9.7 11 0 0 11 11 11 2 Peptidase propeptide and YPEB domain Nop14 PF04147.12 RUS73771.1 - 5.6e-05 21.6 32.7 6.4e-05 21.4 32.7 1.1 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 RUS73771.1 - 9.4e-05 20.7 40.0 0.00016 20.0 40.0 1.3 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 RUS73771.1 - 0.00016 21.3 31.9 0.00021 20.8 31.9 1.2 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 RUS73771.1 - 0.00019 20.4 27.5 0.00022 20.2 27.5 1.1 1 0 0 1 1 1 1 Caldesmon BUD22 PF09073.10 RUS73771.1 - 0.00029 20.3 28.4 0.00039 19.9 28.4 1.2 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 RUS73771.1 - 0.00062 18.2 24.9 0.00075 17.9 24.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 RUS73771.1 - 0.0011 17.6 36.9 0.0014 17.2 36.9 1.1 1 0 0 1 1 1 1 Mpp10 protein Plasmodium_Vir PF05795.11 RUS73771.1 - 0.0027 17.2 9.1 0.0032 16.9 9.1 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SpoIIIAH PF12685.7 RUS73771.1 - 0.0027 17.6 12.3 0.0035 17.2 12.3 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein SpoIIP PF07454.11 RUS73771.1 - 0.0028 17.2 13.4 0.0034 16.9 13.4 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF2151 PF10221.9 RUS73771.1 - 0.0038 15.9 10.5 0.0043 15.7 10.5 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator CCSAP PF15748.5 RUS73771.1 - 0.0096 16.1 15.9 0.013 15.7 15.9 1.3 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated DDHD PF02862.17 RUS73771.1 - 0.012 15.8 4.3 0.017 15.3 4.3 1.4 1 0 0 1 1 1 0 DDHD domain DUF4471 PF14740.6 RUS73771.1 - 0.019 14.2 9.0 0.055 12.7 9.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) Zip PF02535.22 RUS73771.1 - 0.08 12.1 10.0 0.11 11.7 10.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 RUS73771.1 - 0.088 10.9 9.8 0.093 10.8 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 RUS73771.1 - 0.095 12.1 25.7 0.13 11.6 25.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NPR3 PF03666.13 RUS73771.1 - 0.12 11.2 13.8 0.13 11.0 13.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 RUS73771.1 - 0.12 11.3 21.5 0.19 10.7 21.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 RUS73771.1 - 0.12 11.1 17.3 0.16 10.7 17.3 1.2 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 RUS73771.1 - 0.12 11.4 22.4 0.16 11.1 22.4 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 CCDC53 PF10152.9 RUS73771.1 - 0.13 12.7 15.1 0.25 11.8 15.1 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 RUS73771.1 - 0.16 11.9 5.7 0.24 11.4 5.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 RUS73771.1 - 0.27 10.0 22.0 0.38 9.5 22.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 RUS73771.1 - 0.3 10.1 8.8 0.34 9.9 8.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Merozoite_SPAM PF07133.11 RUS73771.1 - 0.34 10.9 65.6 0.57 10.1 65.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Peptidase_S64 PF08192.11 RUS73771.1 - 0.37 9.2 7.6 0.42 9.0 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 ASC PF00858.24 RUS73771.1 - 0.49 9.3 2.4 0.54 9.1 2.4 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel CobT PF06213.12 RUS73771.1 - 0.53 9.6 45.1 0.83 9.0 45.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MDM10 PF12519.8 RUS73771.1 - 0.77 8.6 10.9 0.93 8.3 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RPOL_N PF14700.6 RUS73771.1 - 0.8 9.0 14.3 1.1 8.5 14.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Sec62 PF03839.16 RUS73771.1 - 0.92 9.0 17.0 1.5 8.3 17.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 RUS73771.1 - 1.2 9.6 17.7 0.99 9.8 16.0 1.7 2 0 0 2 2 1 0 RNA polymerase III RPC4 LAP1C PF05609.12 RUS73771.1 - 1.6 7.7 15.2 2 7.4 15.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Paf1 PF03985.13 RUS73771.1 - 1.8 7.5 46.9 2.9 6.8 46.9 1.4 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 RUS73771.1 - 2 8.2 32.0 3.5 7.4 32.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tau95_N PF17682.1 RUS73771.1 - 2.4 8.3 8.2 8.1 6.7 8.2 1.9 1 1 0 1 1 1 0 Tau95 Triple barrel domain Gti1_Pac2 PF09729.9 RUS73771.1 - 2.6 8.1 9.0 3.3 7.8 8.3 1.5 2 0 0 2 2 1 0 Gti1/Pac2 family Vfa1 PF08432.10 RUS73771.1 - 3.7 7.8 26.4 7 6.9 26.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TERB2 PF15101.6 RUS73771.1 - 3.9 7.5 7.6 7.3 6.6 7.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SAPS PF04499.15 RUS73771.1 - 4.2 6.0 17.0 5.3 5.7 17.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 RUS73771.1 - 4.4 7.3 8.1 6.5 6.7 8.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF3_subunit PF08597.10 RUS73771.1 - 4.8 7.0 38.1 7.3 6.4 38.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit IFT57 PF10498.9 RUS73771.1 - 5.9 5.8 32.1 8.3 5.3 32.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF913 PF06025.12 RUS73771.1 - 7.6 5.4 18.0 12 4.8 18.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PTPRCAP PF15713.5 RUS73771.1 - 7.8 6.8 43.6 18 5.6 43.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CCDC84 PF14968.6 RUS73772.1 - 5.8e-14 52.5 0.7 5.8e-14 52.5 0.7 2.2 2 1 0 2 2 2 1 Coiled coil protein 84 FRB_dom PF08771.11 RUS73772.1 - 0.0093 16.4 0.3 0.58 10.6 0.0 2.7 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain AMP-binding PF00501.28 RUS73773.1 - 3.1e-51 174.3 0.0 4.9e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS73773.1 - 3.3e-06 28.0 1.3 1.6e-05 25.8 0.3 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RUS73774.1 - 3.4e-54 184.1 0.2 8.8e-51 172.8 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS73774.1 - 5.2e-07 30.6 0.3 1.4e-06 29.2 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5448 PF17526.2 RUS73774.1 - 0.084 13.1 0.3 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5448) AMP-binding_C_2 PF14535.6 RUS73774.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SLC3A2_N PF16028.5 RUS73775.1 - 0.03 13.9 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Cadherin PF00028.17 RUS73776.1 - 1.5e-13 51.0 4.4 7.9e-09 35.8 0.9 3.1 3 0 0 3 3 3 2 Cadherin domain Cadherin_3 PF16184.5 RUS73776.1 - 0.001 19.1 0.5 0.094 12.7 0.3 2.5 2 0 0 2 2 2 2 Cadherin-like PHTB1_N PF14727.6 RUS73776.1 - 0.034 13.5 0.1 0.056 12.8 0.0 1.5 2 0 0 2 2 2 0 PTHB1 N-terminus Cadherin PF00028.17 RUS73777.1 - 5e-41 139.1 0.6 7.6e-13 48.7 0.0 4.1 4 0 0 4 4 4 3 Cadherin domain Cadherin_2 PF08266.12 RUS73777.1 - 2.2e-05 24.2 0.0 0.041 13.7 0.0 3.6 3 1 1 4 4 4 2 Cadherin-like MitoNEET_N PF10660.9 RUS73779.1 - 1.7e-16 59.9 0.0 2.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 RUS73779.1 - 1.9e-10 40.8 0.1 3.6e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type 7tm_1 PF00001.21 RUS73780.1 - 0.0055 16.1 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_4 PF06779.14 RUS73780.1 - 0.024 13.9 0.2 0.033 13.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB 7tm_1 PF00001.21 RUS73781.1 - 2.7e-12 46.6 6.5 6e-12 45.4 6.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73781.1 - 2.3 7.8 19.5 6.8 6.2 19.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS73782.1 - 1.7e-10 40.7 13.6 4.5e-10 39.3 13.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COesterase PF00135.28 RUS73783.1 - 2.3e-78 264.3 0.1 2.7e-78 264.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS73783.1 - 0.0041 17.0 0.6 0.032 14.1 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold NQR2_RnfD_RnfE PF03116.15 RUS73783.1 - 0.12 11.8 1.7 0.35 10.2 1.7 1.6 1 1 0 1 1 1 0 NQR2, RnfD, RnfE family COesterase PF00135.28 RUS73784.1 - 6.1e-30 104.6 0.0 6.9e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Presenilin PF01080.17 RUS73785.1 - 0.0063 15.3 30.8 0.011 14.5 30.8 1.3 1 0 0 1 1 1 1 Presenilin DNA_methylase PF00145.17 RUS73785.1 - 0.2 10.9 24.5 0.28 10.5 24.5 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase CAC1F_C PF16885.5 RUS73785.1 - 0.22 11.1 12.3 0.31 10.6 12.3 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Dapper PF15268.6 RUS73785.1 - 0.24 10.2 31.4 0.28 10.0 31.4 1.1 1 0 0 1 1 1 0 Dapper SOBP PF15279.6 RUS73785.1 - 0.31 11.6 22.9 0.48 11.0 22.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 RUS73785.1 - 1 7.9 34.8 1.2 7.6 34.8 1.1 1 0 0 1 1 1 0 Macoilin family Mem_trans PF03547.18 RUS73785.1 - 4.1 5.7 8.0 4.9 5.4 8.0 1.2 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 RUS73785.1 - 4.5 4.3 23.5 5.2 4.1 23.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 RUS73785.1 - 5.6 5.0 31.0 7 4.6 31.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CtaG_Cox11 PF04442.14 RUS73786.1 - 6.8e-45 152.8 0.1 9.6e-45 152.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 AIG1 PF04548.16 RUS73787.1 - 4.8e-42 143.7 0.0 1.2e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Hint PF01079.20 RUS73787.1 - 5.3e-34 117.6 0.0 9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Hint module MMR_HSR1 PF01926.23 RUS73787.1 - 6.6e-06 26.2 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 RUS73787.1 - 0.014 14.7 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Septin PCI PF01399.27 RUS73788.1 - 1.3e-19 70.7 0.4 7.6e-19 68.2 0.1 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 RUS73788.1 - 2.6e-13 49.8 5.3 7.9e-13 48.3 5.3 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Porin_3 PF01459.22 RUS73789.1 - 8.3e-50 169.7 0.0 9.3e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Aa_trans PF01490.18 RUS73790.1 - 4.7e-37 127.7 7.3 5.6e-37 127.4 7.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM132D_C PF15706.5 RUS73790.1 - 0.11 12.3 0.4 0.3 10.9 0.4 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4870 PF09685.10 RUS73790.1 - 7.7 6.7 10.1 1.2 9.3 4.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) FDF PF09532.10 RUS73791.1 - 1.1 10.1 7.6 0.16 12.8 1.2 2.1 1 1 1 2 2 2 0 FDF domain MFS_1 PF07690.16 RUS73793.1 - 6.4e-26 91.1 26.6 1.1e-18 67.3 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Galactosyl_T PF01762.21 RUS73794.1 - 3.5e-31 108.5 0.0 5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase FGFR3_TM PF18123.1 RUS73794.1 - 0.17 11.4 1.1 0.34 10.5 1.1 1.4 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain UBX PF00789.20 RUS73795.1 - 7e-16 58.2 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain LRR_4 PF12799.7 RUS73795.1 - 3.3e-13 49.6 33.3 0.00079 19.8 0.3 7.7 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS73795.1 - 9e-13 47.8 20.2 0.013 15.2 0.6 6.0 3 2 2 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 RUS73795.1 - 1.8e-05 24.4 20.6 0.49 10.6 0.4 8.6 8 0 0 8 8 8 2 Leucine Rich repeat UBA PF00627.31 RUS73795.1 - 0.018 14.9 0.1 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain LRR_1 PF00560.33 RUS73795.1 - 0.4 11.4 14.8 7.7 7.5 0.0 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat Sushi PF00084.20 RUS73796.1 - 0.013 16.1 1.3 6.3 7.5 0.1 2.4 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) Arcadin_1 PF18653.1 RUS73796.1 - 0.032 14.3 0.1 2.5 8.2 0.0 2.1 1 1 1 2 2 2 0 Arcadin 1 DUF4334 PF14232.6 RUS73796.1 - 0.76 9.8 3.7 23 5.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4334) UPF0253 PF06786.12 RUS73796.1 - 1.4 9.3 6.7 60 4.0 0.3 4.4 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0253) Med6 PF04934.14 RUS73796.1 - 4.6 7.0 6.9 8.3 6.2 0.7 2.4 1 1 0 2 2 2 0 MED6 mediator sub complex component DERM PF14704.6 RUS73797.1 - 4.6e-40 137.6 5.0 5.3e-40 137.4 5.0 1.0 1 0 0 1 1 1 1 Dermatopontin Fez1 PF06818.15 RUS73798.1 - 1.2e-20 74.8 24.6 1.2e-20 74.8 24.6 2.5 1 1 1 2 2 2 1 Fez1 MAD PF05557.13 RUS73798.1 - 0.0042 15.5 47.5 0.028 12.8 47.4 2.3 1 1 0 1 1 1 1 Mitotic checkpoint protein Lebercilin PF15619.6 RUS73798.1 - 0.086 12.5 58.6 6.2 6.4 18.4 4.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease GBP_C PF02841.14 RUS73798.1 - 1.4 8.3 44.7 0.27 10.6 15.9 2.4 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain TMF_DNA_bd PF12329.8 RUS73798.1 - 1.8 8.6 51.0 0.18 11.8 4.5 5.8 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Ion_trans_2 PF07885.16 RUS73801.1 - 4.2e-29 100.3 21.2 7.6e-16 57.8 5.4 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS73801.1 - 1.6e-08 34.1 7.6 0.00017 20.9 0.1 2.1 2 0 0 2 2 2 2 Ion transport protein COX4 PF02936.14 RUS73801.1 - 0.053 13.5 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Sterol-sensing PF12349.8 RUS73802.1 - 2.3e-49 167.2 9.1 2.3e-49 167.2 9.1 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RUS73802.1 - 5.2e-20 71.2 5.9 5.2e-20 71.2 5.9 1.5 2 0 0 2 2 2 1 Patched family WD40 PF00400.32 RUS73802.1 - 5e-13 49.3 12.5 7e-05 23.5 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73802.1 - 1.7e-06 28.2 0.0 0.047 14.0 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS73802.1 - 0.00096 17.9 0.0 2.5 6.6 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Baculo_F PF12259.8 RUS73802.1 - 0.0073 14.9 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 Baculovirus F protein DUF1513 PF07433.11 RUS73802.1 - 0.05 12.7 0.0 11 5.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) DUF768 PF05589.11 RUS73802.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) PWWP PF00855.17 RUS73803.1 - 8.9e-15 54.9 0.1 8.9e-15 54.9 0.1 2.8 2 2 0 2 2 2 1 PWWP domain zf-CW PF07496.15 RUS73803.1 - 5.9e-14 51.8 9.4 1.9e-13 50.2 9.4 2.0 1 0 0 1 1 1 1 CW-type Zinc Finger ARID PF01388.21 RUS73803.1 - 4.4e-11 43.3 0.1 1.3e-10 41.8 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RT_RNaseH_2 PF17919.1 RUS73804.1 - 4.1e-32 110.2 0.0 8.5e-32 109.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS73804.1 - 5.8e-31 106.9 0.0 1.3e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS73804.1 - 1.5e-20 73.6 0.1 3e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RUS73804.1 - 9.2e-20 71.1 0.0 2.7e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS73804.1 - 1.7e-15 56.9 0.3 3.9e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RUS73804.1 - 1.2e-08 35.1 0.2 2.9e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 RUS73804.1 - 2.3e-05 24.1 0.0 7.1e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Thioredoxin_13 PF18401.1 RUS73804.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF2737 PF10930.8 RUS73804.1 - 0.2 11.2 0.0 0.48 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Citrate_bind PF16114.5 RUS73805.1 - 4.4e-94 313.0 0.1 6.8e-94 312.3 0.1 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Ligase_CoA PF00549.19 RUS73805.1 - 1.7e-16 60.4 0.1 3.6e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.21 RUS73805.1 - 6.2e-12 45.3 0.2 9.2e-10 38.1 0.2 2.2 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 RUS73805.1 - 7.3e-11 42.6 0.0 2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 RUS73805.1 - 1.2e-09 38.0 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RUS73805.1 - 0.0041 16.9 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 RUS73805.1 - 0.021 14.3 0.0 0.058 12.8 0.0 1.7 1 1 1 2 2 2 0 ATP-grasp domain RICTOR_V PF14668.6 RUS73805.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 bZIP_Maf PF03131.17 RUS73806.1 - 3.4e-08 33.9 12.1 3.4e-08 33.9 12.1 4.2 4 1 0 4 4 4 1 bZIP Maf transcription factor bZIP_1 PF00170.21 RUS73806.1 - 4.9e-07 29.8 13.6 1e-06 28.7 13.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS73806.1 - 9.1e-06 25.7 16.7 9.1e-06 25.7 16.7 2.4 2 0 0 2 2 2 1 Basic region leucine zipper JIP_LZII PF16471.5 RUS73806.1 - 0.58 10.4 7.5 0.63 10.3 5.5 2.0 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Spc24 PF08286.11 RUS73806.1 - 1.1 9.5 6.7 2.1 8.6 2.4 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 RUS73806.1 - 4.6 7.3 13.5 0.31 11.0 4.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ank_4 PF13637.6 RUS73808.1 - 4.6e-15 55.8 0.1 0.00015 22.2 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS73808.1 - 5.9e-14 52.4 0.0 0.0001 22.8 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS73808.1 - 4.2e-13 49.2 0.7 2.8e-05 24.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS73808.1 - 2.9e-10 39.5 0.1 0.042 14.4 0.0 7.4 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 RUS73808.1 - 1.5e-08 34.7 2.3 0.015 15.7 0.1 5.2 5 1 0 5 5 5 2 Ankyrin repeat ABC_membrane PF00664.23 RUS73809.1 - 5.2e-50 170.6 17.2 2.1e-36 126.0 9.3 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS73809.1 - 9.8e-45 152.4 0.0 2.3e-22 80.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS73809.1 - 2.4e-08 33.7 7.1 0.00063 19.2 0.4 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RUS73809.1 - 4e-05 24.1 1.5 0.34 11.3 0.4 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 RUS73809.1 - 0.00043 20.9 1.8 0.11 13.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RUS73809.1 - 0.00043 20.0 2.1 0.15 11.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RUS73809.1 - 0.00069 19.5 0.5 0.093 12.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RUS73809.1 - 0.00091 19.3 3.0 0.36 10.9 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS73809.1 - 0.001 19.4 2.9 0.88 9.8 0.1 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RUS73809.1 - 0.002 18.1 0.2 0.76 9.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 RUS73809.1 - 0.0022 18.4 0.1 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RUS73809.1 - 0.0049 16.6 0.1 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS73809.1 - 0.013 15.2 3.3 2.1 8.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 RUS73809.1 - 0.014 15.0 0.5 0.014 15.0 0.5 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 RUS73809.1 - 0.017 14.9 0.9 25 4.5 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 RUS73809.1 - 0.028 13.3 0.4 4.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 RUS73809.1 - 0.039 13.5 0.5 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 RUS73809.1 - 0.042 13.8 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 RUS73809.1 - 0.063 12.8 0.1 6.6 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 RUS73809.1 - 0.15 11.8 0.3 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RUS73809.1 - 0.16 11.2 2.5 3.4 6.9 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 RUS73809.1 - 0.28 11.4 0.9 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 RUS73809.1 - 0.34 11.0 5.9 0.33 11.0 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 RUS73809.1 - 0.41 10.7 1.9 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 RUS73809.1 - 3.1 7.5 5.4 1.5 8.5 0.2 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Oleosin PF01277.17 RUS73809.1 - 3.6 7.4 8.7 1.8 8.3 3.2 2.8 3 0 0 3 3 3 0 Oleosin CBFD_NFYB_HMF PF00808.23 RUS73810.1 - 2.3e-16 59.8 1.1 3.5e-16 59.2 1.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS73810.1 - 3.9e-06 27.2 0.5 3.9e-06 27.2 0.5 2.6 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 AT_hook PF02178.19 RUS73810.1 - 0.056 13.3 4.8 0.15 12.0 4.8 1.8 1 0 0 1 1 1 0 AT hook motif CENP-B_dimeris PF09026.10 RUS73810.1 - 0.19 12.2 7.4 0.65 10.4 7.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 RUS73810.1 - 0.32 10.8 8.4 0.63 9.8 8.4 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 RUS73810.1 - 0.7 7.9 3.4 1.1 7.3 3.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RUS73810.1 - 0.8 9.4 5.1 0.25 11.0 2.0 1.8 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.8 RUS73810.1 - 2.4 6.8 8.0 0.22 10.3 1.6 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.12 RUS73810.1 - 4.6 6.5 8.0 9.7 5.4 8.0 1.5 1 0 0 1 1 1 0 NOA36 protein TT_ORF2 PF02957.15 RUS73810.1 - 4.9 8.1 9.9 15 6.5 8.9 2.3 1 1 0 1 1 1 0 TT viral ORF2 TMCO5 PF14992.6 RUS73811.1 - 0.046 13.3 8.9 0.066 12.8 8.9 1.2 1 0 0 1 1 1 0 TMCO5 family AAA_15 PF13175.6 RUS73811.1 - 1.7 8.3 7.8 3.9 7.1 7.8 1.7 1 1 0 1 1 1 0 AAA ATPase domain Med29 PF11568.8 RUS73812.1 - 2.7e-42 144.3 0.0 3.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 29 Paf1 PF03985.13 RUS73813.1 - 5.6e-129 430.8 52.3 1.2e-126 423.2 52.3 2.7 1 1 0 1 1 1 1 Paf1 PKD_3 PF16820.5 RUS73813.1 - 0.005 16.6 3.3 0.01 15.6 1.6 2.1 2 0 0 2 2 2 1 PKD-like domain Patched PF02460.18 RUS73814.1 - 1.4e-11 43.2 12.9 5.3e-06 24.8 0.7 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RUS73814.1 - 1.1e-07 31.9 17.8 8.5e-05 22.4 4.9 2.6 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 RUS73814.1 - 0.011 14.7 0.6 0.011 14.7 0.6 2.0 2 0 0 2 2 2 0 MMPL family HEPN_LA2681 PF18733.1 RUS73814.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 LA2681-like HEPN Pkinase PF00069.25 RUS73815.1 - 2.4e-27 96.0 0.0 6.3e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS73815.1 - 2.6e-16 59.7 0.0 4.6e-16 58.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS73815.1 - 0.00093 18.6 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 RUS73816.1 - 0.024 14.4 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 MIF4G like GvpG PF05120.12 RUS73816.1 - 0.13 12.2 0.4 22 5.1 0.1 2.3 2 0 0 2 2 2 0 Gas vesicle protein G DUF1435 PF07256.12 RUS73817.1 - 0.17 12.0 3.4 8.9 6.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) XG_FTase PF03254.13 RUS73817.1 - 2.4 6.7 3.8 1.7 7.2 0.5 2.0 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase 7TM_GPCR_Srw PF10324.9 RUS73818.1 - 1.5e-17 63.9 20.9 2e-17 63.5 20.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS73818.1 - 3.4e-17 62.6 21.6 5e-17 62.1 21.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73818.1 - 1.2e-06 28.4 14.6 1.2e-06 28.4 14.6 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TctB PF07331.11 RUS73818.1 - 2.4 8.5 11.7 0.068 13.4 2.3 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family LRR_8 PF13855.6 RUS73819.1 - 4.3e-22 77.6 18.0 5.6e-10 38.8 3.7 5.0 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 RUS73819.1 - 1.8e-15 56.8 27.1 0.00025 21.4 4.0 5.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS73819.1 - 2.8e-09 36.7 6.4 5.1e-06 26.1 0.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RUS73819.1 - 4.4e-08 32.6 24.0 0.22 12.2 0.8 8.1 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_5 PF13306.6 RUS73819.1 - 0.0025 17.8 0.8 0.16 11.9 0.1 2.4 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 RUS73819.1 - 0.0037 17.3 0.3 3.3 7.8 0.0 3.5 3 1 2 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain DUF4116 PF13475.6 RUS73819.1 - 0.059 13.1 0.2 22 4.9 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) LRR_6 PF13516.6 RUS73819.1 - 6.9 7.0 30.0 2.2 8.5 0.2 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Glyco_hydro_38N PF01074.22 RUS73821.1 - 9.6e-89 297.6 4.5 1.5e-88 296.9 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS73821.1 - 4.2e-24 85.8 0.0 8.1e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RUS73821.1 - 1.7e-19 69.7 0.1 4.8e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Ribosomal_S5_C PF03719.15 RUS73822.1 - 5e-18 64.3 0.0 8.5e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 RUS73822.1 - 8.6e-18 64.1 1.1 1.7e-17 63.1 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain SH2_2 PF14633.6 RUS73822.1 - 0.076 12.4 0.3 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 SH2 domain AhpC-TSA_2 PF13911.6 RUS73823.1 - 4.2e-07 30.1 0.0 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme BAR_3 PF16746.5 RUS73823.1 - 0.003 17.3 0.5 0.0044 16.8 0.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family AhpC-TSA PF00578.21 RUS73823.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family DUF148 PF02520.17 RUS73823.1 - 0.31 11.1 1.6 1.6 8.9 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function DUF148 Fcf1 PF04900.12 RUS73824.1 - 2.4e-38 130.5 2.5 3.6e-38 129.9 2.5 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 RUS73824.1 - 5.1e-14 52.6 0.1 7.6e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 RUS73824.1 - 0.018 15.3 0.7 0.064 13.5 0.2 1.9 2 0 0 2 2 2 0 NTF2 fold immunity protein PhyH PF05721.13 RUS73825.1 - 2.1e-21 77.2 0.0 3.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 RUS73825.1 - 0.00098 20.0 0.0 0.0019 19.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 RUS73825.1 - 0.002 18.5 0.2 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase NOA36 PF06524.12 RUS73826.1 - 0.028 13.7 22.4 0.056 12.8 22.4 1.5 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RUS73826.1 - 0.13 11.8 8.2 0.2 11.2 8.2 1.4 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 RUS73826.1 - 0.43 10.4 9.5 0.7 9.7 9.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 RUS73826.1 - 1 8.7 11.8 1.5 8.2 11.8 1.3 1 0 0 1 1 1 0 SDA1 DUF2076 PF09849.9 RUS73826.1 - 1.8 8.5 14.7 2.7 8.0 14.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cwf_Cwc_15 PF04889.12 RUS73826.1 - 3.9 7.1 27.7 0.56 9.9 23.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RUS73826.1 - 9.4 4.3 16.0 12 4.0 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family Clathrin_bdg PF15045.6 RUS73827.1 - 2e-08 34.1 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 Clathrin-binding box of Aftiphilin, vesicle trafficking FIBP PF05427.11 RUS73828.1 - 1.3e-146 488.6 9.2 1.4e-146 488.4 9.2 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) SAM_1 PF00536.30 RUS73829.1 - 5.9e-12 45.8 0.0 8.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS73829.1 - 6.8e-10 38.9 0.0 9.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_1 PF00013.29 RUS73830.1 - 4.6e-09 36.0 0.2 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 KH domain Qua1 PF16274.5 RUS73830.1 - 0.0015 18.3 0.4 0.0031 17.3 0.4 1.6 1 0 0 1 1 1 1 Qua1 domain KH_4 PF13083.6 RUS73830.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 KH domain DM PF00751.18 RUS73832.1 - 4.6e-22 77.7 12.7 1e-21 76.6 12.7 1.6 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 RUS73832.1 - 3.3e-10 39.4 0.0 5.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif JAB PF01398.21 RUS73833.1 - 4.3e-11 42.8 0.3 9.5e-11 41.7 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 RUS73833.1 - 4e-07 29.8 0.0 4e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RUS73833.1 - 0.002 18.2 0.7 0.0049 16.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) zf-HIT PF04438.16 RUS73834.1 - 5.1e-08 32.6 14.1 1.2e-07 31.5 14.1 1.6 1 0 0 1 1 1 1 HIT zinc finger DUF4201 PF13870.6 RUS73835.1 - 4.4e-38 130.8 34.8 8e-38 129.9 22.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 RUS73835.1 - 0.0011 19.0 2.1 0.0011 19.0 2.1 3.2 3 1 1 4 4 4 1 TolA binding protein trimerisation MscS_porin PF12795.7 RUS73835.1 - 0.36 10.3 14.8 0.065 12.8 2.3 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 RUS73835.1 - 0.57 10.6 18.0 0.06 13.7 2.9 4.9 3 2 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF883 PF05957.13 RUS73835.1 - 3.9 8.1 6.2 1.7 9.3 2.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.7 RUS73836.1 - 6.9e-08 32.3 0.1 1.7e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS73836.1 - 4.5e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3506 PF12014.8 RUS73836.1 - 6.5e-05 23.0 0.3 0.014 15.4 0.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box_4 PF15966.5 RUS73836.1 - 0.0015 18.4 0.1 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 F-box PHD_2 PF13831.6 RUS73837.1 - 6.1e-06 25.7 4.0 1.3e-05 24.7 4.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS73837.1 - 6.6e-05 22.7 7.1 0.00012 21.9 7.1 1.4 1 0 0 1 1 1 1 PHD-finger DUF1804 PF08822.11 RUS73838.1 - 0.012 15.5 3.2 0.055 13.5 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1804) DUF2730 PF10805.8 RUS73838.1 - 0.31 11.1 7.8 0.27 11.3 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Guanylate_kin PF00625.21 RUS73839.1 - 4.1e-43 147.2 0.2 1.5e-42 145.4 0.2 1.8 1 1 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 RUS73839.1 - 2.8e-11 43.6 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS73839.1 - 1e-05 25.3 0.0 4.2e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS73839.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF2437 PF10370.9 RUS73839.1 - 0.024 15.5 0.0 0.076 13.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) L27 PF02828.16 RUS73839.1 - 0.038 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 L27 domain RNA_pol_I_A49 PF06870.12 RUS73840.1 - 1e-55 189.2 0.3 1.2e-55 189.0 0.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Fibrinogen_C PF00147.18 RUS73841.1 - 6.3e-23 81.7 0.7 7.6e-23 81.5 0.7 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4525 PF15027.6 RUS73842.1 - 0.08 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) 7tm_1 PF00001.21 RUS73843.1 - 7e-09 35.4 11.9 9.7e-09 34.9 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73843.1 - 2.4e-06 27.4 15.7 4.2e-06 26.6 15.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4094 PF13334.6 RUS73843.1 - 0.16 12.4 0.1 0.43 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) K1 PF02960.14 RUS73843.1 - 0.26 11.4 2.2 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 K1 glycoprotein 7TM_GPCR_Srw PF10324.9 RUS73844.1 - 2.3e-10 40.3 21.0 4.9e-10 39.2 21.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS73844.1 - 3.8e-08 33.3 22.8 4.8e-08 32.9 21.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS73844.1 - 2.2e-07 30.5 17.0 3e-07 30.0 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trm112p PF03966.16 RUS73845.1 - 1.9e-17 63.6 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein KRBA1 PF15287.6 RUS73847.1 - 5.6 6.7 8.5 4.1 7.2 0.5 3.4 3 0 0 3 3 3 0 KRBA1 family repeat Cloacin_immun PF03513.14 RUS73848.1 - 0.0027 18.0 0.0 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 Cloacin immunity protein AA_permease_2 PF13520.6 RUS73849.1 - 5.6e-16 58.4 31.3 6.7e-16 58.1 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS73849.1 - 5.7e-05 21.9 27.5 6.9e-05 21.6 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease CAP_GLY PF01302.25 RUS73850.1 - 2.2e-11 43.6 0.2 3.5e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain PhoLip_ATPase_C PF16212.5 RUS73851.1 - 2.9e-48 164.8 21.7 2.9e-48 164.8 21.7 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RUS73851.1 - 4.4e-20 71.1 2.2 1.4e-19 69.5 2.2 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 RUS73851.1 - 1.4e-14 54.0 0.8 2.9e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RUS73851.1 - 2.1e-14 54.3 0.2 5e-06 26.9 0.1 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RUS73851.1 - 3.4e-10 39.9 0.1 3e-08 33.6 0.0 3.1 3 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RUS73851.1 - 0.01 15.6 0.4 0.033 13.9 0.0 2.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TPT PF03151.16 RUS73853.1 - 2.5e-17 63.2 20.7 3e-17 62.9 20.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS73853.1 - 6.8e-06 26.3 33.4 0.0068 16.6 14.6 2.7 2 1 1 3 3 3 2 EamA-like transporter family ANAPC1 PF12859.7 RUS73854.1 - 0.15 12.7 10.6 0.18 12.4 10.6 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF4834 PF16118.5 RUS73854.1 - 0.39 11.7 2.1 0.5 11.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Branch PF02485.21 RUS73855.1 - 2.4e-39 135.4 0.1 3.3e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme PMEI PF04043.15 RUS73855.1 - 0.21 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Bgal_small_N PF02929.17 RUS73857.1 - 0.021 14.4 0.2 13 5.3 0.1 3.0 3 0 0 3 3 3 0 Beta galactosidase small chain PHF5 PF03660.14 RUS73857.1 - 1.6 9.0 5.4 22 5.3 0.5 2.8 1 1 1 2 2 2 0 PHF5-like protein Lipocalin PF00061.23 RUS73858.1 - 2.1e-12 47.4 0.1 2.7e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS73858.1 - 0.00019 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4857 PF16149.5 RUS73858.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) PAN_1 PF00024.26 RUS73859.1 - 0.00041 20.3 1.6 0.00059 19.7 0.7 1.7 2 0 0 2 2 2 1 PAN domain SRCR_2 PF15494.6 RUS73859.1 - 0.021 15.4 0.8 5.3 7.7 0.0 2.9 2 1 1 3 3 3 0 Scavenger receptor cysteine-rich domain PAN_3 PF08277.12 RUS73859.1 - 0.025 14.4 0.5 0.043 13.6 0.5 1.3 1 0 0 1 1 1 0 PAN-like domain Lectin_C PF00059.21 RUS73859.1 - 0.059 14.1 0.1 0.39 11.5 0.0 2.0 2 0 0 2 2 2 0 Lectin C-type domain PAN_4 PF14295.6 RUS73859.1 - 0.071 13.0 0.6 0.17 11.8 0.6 1.6 1 0 0 1 1 1 0 PAN domain Tropomyosin_1 PF12718.7 RUS73860.1 - 2.5e-12 47.1 23.0 0.0002 21.5 0.5 5.2 1 1 5 6 6 6 5 Tropomyosin like Tropomyosin PF00261.20 RUS73860.1 - 4.3e-12 45.9 30.0 7.3e-06 25.5 3.8 3.4 1 1 1 3 3 3 3 Tropomyosin Sugarporin_N PF11471.8 RUS73860.1 - 3.7e-11 42.8 18.4 5.4 7.0 0.0 14.6 7 6 5 16 16 16 2 Maltoporin periplasmic N-terminal extension FPP PF05911.11 RUS73860.1 - 0.071 11.3 37.2 0.05 11.8 6.2 3.1 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil zinc_ribbon_4 PF13717.6 RUS73860.1 - 0.24 11.3 2.3 4.6 7.2 0.1 4.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF745 PF05335.13 RUS73860.1 - 0.82 9.4 34.8 0.12 12.1 3.5 5.2 3 1 1 5 5 5 0 Protein of unknown function (DUF745) CBP_BcsR PF10945.8 RUS73860.1 - 3 7.4 19.4 4.2 6.9 0.2 6.5 6 1 1 7 7 7 0 Cellulose biosynthesis protein BcsR CH PF00307.31 RUS73861.1 - 8.5e-19 67.8 0.0 1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS73861.1 - 2.5e-07 30.5 0.0 4.4e-07 29.6 0.0 1.4 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 RUS73861.1 - 0.037 14.1 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 CH-like domain in sperm protein I-set PF07679.16 RUS73862.1 - 3.1e-72 238.7 0.0 2.4e-20 72.4 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS73862.1 - 4.5e-45 152.2 4.4 1.2e-12 48.2 0.0 6.3 5 1 1 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 RUS73862.1 - 1.8e-31 108.3 0.3 3.3e-09 36.9 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS73862.1 - 3.5e-21 75.2 14.3 7.4e-08 32.5 0.0 5.7 6 0 0 6 6 5 4 Immunoglobulin domain Smoothelin PF12510.8 RUS73862.1 - 1.2e-11 44.4 0.5 2.8e-11 43.3 0.5 1.6 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein V-set PF07686.17 RUS73862.1 - 6.3e-08 32.8 13.5 0.14 12.4 0.0 7.8 5 4 2 7 7 6 2 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS73862.1 - 7.7e-07 29.4 0.5 0.061 13.7 0.1 4.1 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS73862.1 - 2.6e-06 27.6 0.1 0.047 14.0 0.0 4.3 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 RUS73862.1 - 0.0017 18.3 0.1 9.4 6.4 0.0 4.0 4 0 0 4 4 4 1 C17orf99 Ig domain Ig_6 PF18452.1 RUS73862.1 - 0.003 17.1 0.4 1.3 8.6 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 RUS73862.1 - 0.011 15.7 0.1 0.48 10.5 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain NCD3G PF07562.14 RUS73863.1 - 0.06 13.3 3.6 0.14 12.1 3.6 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF776 PF05604.11 RUS73863.1 - 0.16 12.4 1.0 23 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF776) HTH_33 PF13592.6 RUS73863.1 - 4.1 7.1 5.2 28 4.4 0.5 2.4 2 0 0 2 2 2 0 Winged helix-turn helix NCD3G PF07562.14 RUS73864.1 - 0.025 14.6 3.6 0.052 13.5 3.6 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR PAM2 PF07145.15 RUS73865.1 - 0.0055 16.3 1.7 0.0087 15.7 0.1 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region TILa PF12714.7 RUS73866.1 - 4.5e-07 29.7 19.1 0.00023 21.1 6.6 2.7 2 0 0 2 2 2 2 TILa domain VWC PF00093.18 RUS73866.1 - 5.6e-06 26.6 26.7 0.00015 22.0 5.4 2.5 2 0 0 2 2 2 2 von Willebrand factor type C domain CFC PF09443.10 RUS73866.1 - 0.00011 22.0 14.3 0.0096 15.7 3.8 2.8 2 0 0 2 2 2 2 Cripto_Frl-1_Cryptic (CFC) Pentapeptide_4 PF13599.6 RUS73867.1 - 7.5e-16 58.1 0.0 0.0013 18.8 0.0 4.5 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 RUS73867.1 - 5.7e-08 32.2 0.0 2.9 7.6 0.0 6.1 4 2 1 6 6 6 4 Pentapeptide repeats (8 copies) Nucleoporin2 PF04096.14 RUS73867.1 - 0.0043 17.2 3.3 33 4.6 0.2 5.8 1 1 3 4 4 4 0 Nucleoporin autopeptidase RHH_8 PF17723.1 RUS73867.1 - 0.024 14.8 40.1 35 4.6 0.9 11.6 1 1 7 8 8 8 0 Ribbon-Helix-Helix transcriptional regulator family LRR_4 PF12799.7 RUS73867.1 - 0.17 12.3 36.0 1.8e+04 -21.3 36.0 6.9 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) TrmO PF01980.16 RUS73867.1 - 5 7.4 13.9 90 3.3 0.1 5.8 1 1 4 5 5 5 0 tRNA-methyltransferase O PARP PF00644.20 RUS73868.1 - 1.9e-72 243.0 0.6 3.6e-72 242.1 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RUS73868.1 - 4e-48 162.9 1.3 2e-47 160.7 1.3 2.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 RUS73868.1 - 1.9e-31 108.8 2.6 1.8e-16 60.8 0.5 3.8 4 0 0 4 4 4 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 RUS73868.1 - 5.3e-21 74.2 2.4 5.3e-21 74.2 2.4 2.0 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.15 RUS73868.1 - 1.2e-18 66.9 0.4 1.2e-18 66.9 0.4 2.7 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 RUS73868.1 - 1.5e-09 38.1 0.2 3.1e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS73868.1 - 1.5e-05 25.3 0.0 4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SmAKAP PF15127.6 RUS73868.1 - 1.1 10.5 3.9 0.43 11.8 0.5 2.1 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein Peptidase_C65 PF10275.9 RUS73869.1 - 2.8e-76 256.2 0.1 3.3e-76 256.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 RUS73869.1 - 7.9e-06 26.4 0.3 0.0002 21.8 0.0 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Spectrin PF00435.21 RUS73869.1 - 0.018 15.5 1.3 0.031 14.8 1.3 1.3 1 0 0 1 1 1 0 Spectrin repeat zf-C2H2_4 PF13894.6 RUS73870.1 - 2.5e-36 121.2 156.7 0.0003 21.4 0.7 19.4 19 0 0 19 19 19 16 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS73870.1 - 7.8e-35 117.4 165.1 6.7e-05 23.1 0.3 19.4 19 1 0 19 19 18 15 Zinc finger, C2H2 type zf-Di19 PF05605.12 RUS73870.1 - 2.3e-16 59.8 113.3 1.9e-05 24.9 1.6 12.7 6 4 6 12 12 11 6 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS73870.1 - 2.8e-12 46.5 159.2 0.00085 19.6 0.3 19.6 21 1 0 21 21 20 9 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS73870.1 - 1.4e-08 34.8 96.2 0.03 14.6 1.0 15.9 17 0 0 17 17 15 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS73870.1 - 7.1e-05 23.1 11.0 0.0014 19.0 1.2 17.5 19 0 0 19 19 19 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS73870.1 - 0.013 15.8 8.6 0.013 15.8 8.6 14.1 2 2 8 11 11 10 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RUS73870.1 - 0.016 15.1 0.1 0.016 15.1 0.1 13.5 17 0 0 17 17 16 0 zinc-finger of a C2HC-type DNA_pol_D_N PF18018.1 RUS73870.1 - 0.016 15.3 0.1 1.9 8.6 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Zn-C2H2_12 PF18112.1 RUS73870.1 - 0.59 10.6 0.0 0.59 10.6 0.0 11.1 12 0 0 12 12 11 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 RUS73870.1 - 1.5 9.6 77.2 0.72 10.6 1.7 10.2 2 2 6 9 9 8 0 zinc-ribbon family GcpE PF04551.14 RUS73870.1 - 7.1 5.6 11.4 0.19 10.8 0.1 3.0 3 1 0 3 3 3 0 GcpE protein zf-C2H2_4 PF13894.6 RUS73871.1 - 3.1e-25 86.7 125.9 0.0027 18.4 0.3 16.4 16 0 0 16 16 16 10 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS73871.1 - 1.2e-20 72.8 133.2 0.00034 20.9 0.3 16.9 16 2 0 16 16 16 10 Zinc finger, C2H2 type zf-Di19 PF05605.12 RUS73871.1 - 1.1e-05 25.6 16.8 0.00028 21.1 1.4 10.6 5 3 7 12 12 11 6 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS73871.1 - 3.4e-05 24.1 4.8 0.00058 20.2 0.3 17.4 18 1 0 18 18 18 6 Zinc-finger double domain zf-C2H2_11 PF16622.5 RUS73871.1 - 5.8e-05 22.8 3.0 5.8e-05 22.8 3.0 11.8 13 0 0 13 13 13 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS73871.1 - 0.00025 21.0 2.0 0.0034 17.3 0.5 13.7 15 1 0 15 15 13 6 C2H2-type zinc finger zf-met PF12874.7 RUS73871.1 - 0.00027 21.2 2.7 0.0009 19.6 0.5 13.2 14 0 0 14 14 14 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS73871.1 - 0.0023 18.2 0.3 0.068 13.5 0.0 12.3 13 1 0 13 13 11 5 Zinc-finger double-stranded RNA-binding zf-WRNIP1_ubi PF18279.1 RUS73871.1 - 0.011 16.3 0.6 0.011 16.3 0.6 7.5 9 0 0 9 9 8 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf_UBZ PF18439.1 RUS73871.1 - 0.012 15.2 0.1 0.012 15.2 0.1 13.6 14 0 0 14 14 14 0 Ubiquitin-Binding Zinc Finger Ribosomal_L28 PF00830.19 RUS73871.1 - 3.7 7.8 8.0 1.4 9.1 0.3 3.8 3 0 0 3 3 3 0 Ribosomal L28 family zf-C2H2_3rep PF18868.1 RUS73871.1 - 7.7 7.2 53.6 2.3 8.9 2.4 7.9 2 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats ALO PF04030.14 RUS73873.1 - 2.9e-08 33.8 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase bZIP_2 PF07716.15 RUS73874.1 - 4.5e-06 26.6 18.7 1.2e-05 25.3 18.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS73874.1 - 1e-05 25.5 18.1 3e-05 24.0 18.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS73874.1 - 0.00054 20.4 15.0 0.00054 20.4 15.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Secretin_N_2 PF07655.13 RUS73874.1 - 2.1 8.9 19.6 9.7 6.8 19.6 2.2 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4407 PF14362.6 RUS73874.1 - 4.3 6.6 7.1 4.1 6.7 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 RUS73875.1 - 1e-06 28.7 18.3 1.9e-06 27.8 18.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS73875.1 - 8.6e-06 26.2 15.9 2e-05 25.0 15.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 RUS73875.1 - 0.0047 17.0 21.3 0.01 15.9 21.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper YceD PF02620.17 RUS73875.1 - 0.28 11.3 1.5 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD CagX PF03524.15 RUS73876.1 - 0.039 13.7 0.1 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Spt20 PF12090.8 RUS73876.1 - 0.73 9.4 8.8 1.3 8.6 8.8 1.3 1 0 0 1 1 1 0 Spt20 family PI-PLC-X PF00388.19 RUS73878.1 - 2.5e-64 215.2 0.1 2.5e-64 215.2 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RUS73878.1 - 8.3e-40 135.7 0.1 8.3e-40 135.7 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 RUS73878.1 - 3.8e-29 101.2 0.3 3.8e-29 101.2 0.3 2.1 2 0 0 2 2 2 1 PH domain PLC-beta_C PF08703.10 RUS73878.1 - 1.4e-15 57.7 24.6 1.4e-15 57.7 24.6 3.5 3 0 0 3 3 3 1 PLC-beta C terminal EF-hand_like PF09279.11 RUS73878.1 - 2.1e-14 53.8 0.0 2.1e-14 53.8 0.0 4.1 4 1 1 5 5 5 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 RUS73878.1 - 3e-06 27.4 0.0 1.1e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF1154 PF06631.11 RUS73878.1 - 9.2e-05 22.4 0.4 9.2e-05 22.4 0.4 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1154) EF-hand_8 PF13833.6 RUS73878.1 - 1.1 9.2 3.5 16 5.4 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair Laminin_EGF PF00053.24 RUS73879.1 - 1.2e-08 34.9 163.2 0.18 12.0 19.4 9.8 1 1 10 11 11 11 8 Laminin EGF domain Spermine_synth PF01564.17 RUS73881.1 - 6e-47 159.5 0.0 1.1e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 RUS73881.1 - 2.7e-23 81.6 0.3 5.6e-23 80.6 0.3 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 RUS73881.1 - 3.3e-05 24.5 0.2 0.00022 21.9 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 RUS73881.1 - 0.0042 16.7 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RUS73881.1 - 0.011 16.5 0.1 0.032 15.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 RUS73881.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CRM1_repeat_2 PF18784.1 RUS73881.1 - 0.06 13.0 0.1 0.28 10.9 0.1 2.1 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 DUF43 PF01861.16 RUS73881.1 - 0.09 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain AA_synth PF06684.11 RUS73881.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Amino acid synthesis Proteasom_Rpn13 PF04683.13 RUS73883.1 - 6.5e-34 116.3 0.2 9.8e-34 115.8 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 RUS73883.1 - 3.5e-17 62.6 4.1 3.5e-17 62.6 4.1 2.1 2 1 0 2 2 2 1 UCH-binding domain L_biotic_typeA PF04604.13 RUS73883.1 - 0.23 11.3 0.7 0.55 10.1 0.7 1.6 1 0 0 1 1 1 0 Type-A lantibiotic GMC_oxred_N PF00732.19 RUS73884.1 - 2.2e-56 191.4 0.0 2.1e-37 129.1 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 RUS73884.1 - 2.9e-42 144.6 0.1 4.9e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 RUS73884.1 - 9.3e-05 22.6 0.2 0.00025 21.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RUS73884.1 - 0.00044 19.4 0.1 0.00065 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RUS73884.1 - 0.0022 17.6 0.0 0.012 15.3 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS73884.1 - 0.029 13.6 0.0 0.087 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS73884.1 - 0.052 12.6 0.2 0.11 11.6 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Abhydrolase_6 PF12697.7 RUS73884.1 - 0.061 13.9 2.3 0.088 13.4 0.1 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family HI0933_like PF03486.14 RUS73884.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 RUS73884.1 - 0.18 11.0 0.0 19 4.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 7tm_1 PF00001.21 RUS73887.1 - 2.4e-08 33.6 26.5 1.5e-07 31.0 14.7 2.5 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS73887.1 - 3.2e-07 30.3 41.6 1.2e-05 25.1 17.1 3.4 2 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx DUF3525 PF12039.8 RUS73887.1 - 0.1 11.3 0.4 11 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Rhodanese PF00581.20 RUS73887.1 - 0.18 12.3 0.0 36 5.0 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain Fanconi_A PF03511.14 RUS73887.1 - 3.8 7.5 7.4 22 5.0 0.9 2.7 2 0 0 2 2 2 0 Fanconi anaemia group A protein CENP-Q PF13094.6 RUS73888.1 - 0.079 13.2 5.0 0.19 11.9 5.0 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_p74 PF04583.12 RUS73888.1 - 0.4 10.1 4.6 0.72 9.3 4.6 1.5 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Sulfotransfer_1 PF00685.27 RUS73889.1 - 1.9e-17 63.7 0.0 2.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS73889.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family bZIP_2 PF07716.15 RUS73890.1 - 7.3e-15 54.8 11.5 7.3e-15 54.8 11.5 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS73890.1 - 8.7e-05 22.5 7.8 0.00016 21.7 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor SR-25 PF10500.9 RUS73890.1 - 0.014 15.1 13.0 0.017 14.7 13.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.11 RUS73890.1 - 0.036 12.9 3.7 0.043 12.7 3.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cnn_1N PF07989.11 RUS73890.1 - 0.045 13.9 0.7 0.1 12.8 0.6 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Glyco_hydro_18 PF00704.28 RUS73891.1 - 3.3e-77 260.3 0.0 4.2e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Recep_L_domain PF01030.24 RUS73892.1 - 7.2e-19 68.0 0.0 1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Receptor L domain Furin-like PF00757.20 RUS73892.1 - 3.2e-14 53.1 16.5 5.4e-14 52.3 16.5 1.3 1 0 0 1 1 1 1 Furin-like cysteine rich region GF_recep_IV PF14843.6 RUS73892.1 - 0.014 15.2 18.1 0.029 14.2 18.1 1.6 1 0 0 1 1 1 0 Growth factor receptor domain IV LpxD PF04613.14 RUS73892.1 - 0.21 11.4 0.0 9.6 6.1 0.0 2.5 3 0 0 3 3 3 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Recep_L_domain PF01030.24 RUS73893.1 - 7e-09 35.8 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Receptor L domain IBR PF01485.21 RUS73894.1 - 2e-20 72.8 19.1 1.4e-12 47.6 0.3 5.7 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Ank_2 PF12796.7 RUS73894.1 - 1.9e-13 50.8 7.1 1.2e-08 35.4 0.5 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS73894.1 - 1.4e-09 38.0 0.1 2.6e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS73894.1 - 1.6e-09 38.1 1.9 0.0033 18.0 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS73894.1 - 3.4e-08 33.6 0.3 0.019 15.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RUS73894.1 - 3.3e-07 30.1 0.3 0.32 11.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat zf-C3HC4_2 PF13923.6 RUS73894.1 - 0.0004 20.2 5.1 0.0004 20.2 5.1 4.9 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS73894.1 - 0.00046 20.5 9.3 0.00046 20.5 9.3 4.8 4 1 1 5 5 4 2 Ring finger domain zf-RING_UBOX PF13445.6 RUS73894.1 - 0.0022 17.9 6.6 0.0022 17.9 6.6 4.0 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS73894.1 - 0.0034 17.2 7.0 0.0034 17.2 7.0 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS73894.1 - 2 8.2 9.3 7.2 6.5 7.9 2.8 2 0 0 2 2 2 0 RING-like zinc finger UIM PF02809.20 RUS73894.1 - 9.9 6.3 7.1 10 6.3 1.2 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif 7tm_1 PF00001.21 RUS73895.1 - 6.7e-32 110.8 0.0 9.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS73895.1 - 3.8e-09 36.3 0.9 5.6e-09 35.8 0.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS73895.1 - 3.3e-06 26.9 0.4 3.3e-06 26.9 0.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS73895.1 - 0.00016 21.5 2.7 0.00028 20.7 2.7 1.4 1 0 0 1 1 1 1 Olfactory receptor Thioredoxin_6 PF13848.6 RUS73896.1 - 1.4e-42 145.7 0.0 2.4e-39 135.1 0.0 2.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 RUS73896.1 - 1.2e-20 73.4 0.0 2.8e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Calsequestrin PF01216.17 RUS73896.1 - 3.3e-08 33.0 0.0 4.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 RUS73896.1 - 0.0083 16.6 0.0 0.023 15.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 RUS73896.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RUS73896.1 - 0.11 12.9 0.0 4.6 7.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like p450 PF00067.22 RUS73897.1 - 2.2e-69 234.4 0.1 1.1e-41 143.0 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Skp1 PF01466.19 RUS73897.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Glyco_hydro_59 PF02057.15 RUS73898.1 - 6.1e-81 271.9 8.4 8e-81 271.5 8.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 RUS73898.1 - 1.3e-32 112.3 0.0 2.2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Laminin_G_2 PF02210.24 RUS73898.1 - 0.017 15.7 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain YccV-like PF08755.11 RUS73899.1 - 2.3e-25 88.9 0.1 1e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 RUS73899.1 - 2.2e-23 82.6 0.0 1.4e-22 79.9 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 RUS73899.1 - 0.00029 20.6 0.2 0.00094 19.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS73899.1 - 0.16 11.9 2.8 1 9.4 2.8 2.2 1 1 0 1 1 1 0 F-box domain bZIP_2 PF07716.15 RUS73901.1 - 2.4e-15 56.3 9.5 2.4e-15 56.3 9.5 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS73901.1 - 3.6e-06 27.0 8.1 1.1e-05 25.4 8.1 1.9 1 0 0 1 1 1 1 bZIP transcription factor Rubella_Capsid PF05750.11 RUS73901.1 - 4.6e-05 23.2 24.1 0.002 17.8 1.8 3.0 3 0 0 3 3 3 2 Rubella capsid protein Chorion_2 PF03964.15 RUS73901.1 - 0.0038 18.1 0.8 0.0038 18.1 0.8 2.9 2 1 1 3 3 3 1 Chorion family 2 DUF5327 PF17261.2 RUS73901.1 - 0.22 12.3 18.0 1.7 9.4 2.6 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5327) DUF3602 PF12223.8 RUS73901.1 - 0.54 10.9 17.6 5.8 7.6 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3602) Myosin-VI_CBD PF16521.5 RUS73901.1 - 4.2 7.4 8.9 11 6.1 1.5 2.3 2 0 0 2 2 2 0 Myosin VI cargo binding domain DUF2526 PF10735.9 RUS73901.1 - 7.1 6.9 20.0 2 8.6 2.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2526) LicD PF04991.13 RUS73902.1 - 2.9e-18 66.8 0.3 1e-12 48.7 0.3 2.3 2 0 0 2 2 2 2 LicD family WD40 PF00400.32 RUS73904.1 - 1e-23 83.1 13.8 6.2e-07 30.0 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS73904.1 - 0.00013 22.1 0.0 0.45 10.8 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RUS73904.1 - 0.055 11.8 0.0 0.13 10.6 0.0 1.5 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz K_channel_TID PF07941.11 RUS73904.1 - 2.2 8.8 10.6 9.2 6.8 8.3 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Plasmodium_HRP PF05403.11 RUS73905.1 - 0.00079 19.3 10.4 0.0024 17.7 10.4 1.7 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) DUF3712 PF12505.8 RUS73905.1 - 0.15 12.3 0.8 5.2 7.4 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3712) EF-hand_6 PF13405.6 RUS73906.1 - 4.3e-05 23.1 1.2 9.7e-05 22.0 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RUS73906.1 - 0.0056 17.1 0.2 0.008 16.6 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS73906.1 - 0.041 13.7 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 RUS73906.1 - 0.065 12.8 0.4 0.19 11.4 0.4 1.8 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 RUS73906.1 - 0.094 13.0 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region His_Phos_2 PF00328.22 RUS73907.1 - 4.8e-06 26.2 0.0 5.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3019 PF11456.8 RUS73908.1 - 0.012 16.1 0.4 0.53 10.8 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3019) DUF5645 PF18713.1 RUS73908.1 - 0.021 15.1 0.0 34 4.8 0.0 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF5645) DUF1472 PF07339.12 RUS73908.1 - 0.027 15.0 2.0 19 5.9 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1472) CotJB PF12652.7 RUS73908.1 - 0.14 12.4 0.2 20 5.5 0.0 3.1 3 0 0 3 3 3 0 CotJB protein SpoIISB_antitox PF14185.6 RUS73908.1 - 0.23 11.4 1.7 86 3.1 0.0 3.7 4 0 0 4 4 4 0 Antitoxin SpoIISB, type II toxin-antitoxin system MSSP PF03940.13 RUS73909.1 - 0.0049 16.4 5.2 0.0067 16.0 5.2 1.2 1 0 0 1 1 1 1 Male specific sperm protein CsbD PF05532.12 RUS73909.1 - 0.019 14.9 4.7 3.2 7.7 0.9 3.0 1 1 1 2 2 2 0 CsbD-like Alanine_zipper PF11839.8 RUS73909.1 - 0.096 13.1 2.8 0.13 12.6 2.8 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein HemY_N PF07219.13 RUS73909.1 - 0.32 11.2 7.4 0.41 10.9 7.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus ANF_receptor PF01094.28 RUS73911.1 - 4.3e-15 55.7 0.0 5.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS73911.1 - 0.00022 21.0 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 RUS73912.1 - 1.5e-15 57.1 0.1 2.5e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Holin_BhlA PF10960.8 RUS73912.1 - 7.5e-05 22.6 2.7 27 4.8 0.0 4.2 4 0 0 4 4 4 4 BhlA holin family Rhabdo_ncap_2 PF03216.13 RUS73912.1 - 0.013 15.0 0.0 81 2.5 0.0 3.9 4 0 0 4 4 4 0 Rhabdovirus nucleoprotein Tannase PF07519.11 RUS73912.1 - 0.14 11.0 0.2 95 1.7 0.0 3.5 4 0 0 4 4 4 0 Tannase and feruloyl esterase ANF_receptor PF01094.28 RUS73913.1 - 1.2e-13 50.9 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS73913.1 - 1.5e-05 24.8 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Acyl_transf_3 PF01757.22 RUS73914.1 - 9.8e-15 54.4 13.7 9.8e-15 54.4 13.7 1.5 2 0 0 2 2 2 1 Acyltransferase family DUF3377 PF11857.8 RUS73914.1 - 0.077 12.9 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Acyl_transf_3 PF01757.22 RUS73915.1 - 1.1e-19 70.7 38.9 1.1e-19 70.7 38.9 1.5 2 0 0 2 2 2 1 Acyltransferase family TB2_DP1_HVA22 PF03134.19 RUS73915.1 - 6.1 6.8 9.3 2.5 8.1 4.4 3.0 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Acyl_transf_3 PF01757.22 RUS73916.1 - 2.1e-20 73.1 34.0 2.7e-20 72.7 34.0 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF4044 PF13253.6 RUS73916.1 - 0.65 9.6 2.5 1.6 8.3 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Acyl_transf_3 PF01757.22 RUS73918.1 - 2.5e-19 69.5 47.6 4.4e-19 68.7 47.6 1.4 1 0 0 1 1 1 1 Acyltransferase family MFS_1 PF07690.16 RUS73919.1 - 1.2e-19 70.5 19.8 6.4e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4755 PF15947.5 RUS73919.1 - 0.0061 16.5 0.2 0.0061 16.5 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4755) Fibrinogen_C PF00147.18 RUS73920.1 - 1.7e-157 521.7 30.8 6.6e-51 173.2 2.2 4.0 3 1 1 4 4 4 4 Fibrinogen beta and gamma chains, C-terminal globular domain PA14 PF07691.12 RUS73920.1 - 0.0013 18.6 14.6 2.7 7.8 0.4 4.2 3 1 1 4 4 4 4 PA14 domain RT_RNaseH_2 PF17919.1 RUS73921.1 - 3.9e-22 78.2 0.1 1.1e-21 76.8 0.1 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS73921.1 - 2.9e-21 75.8 0.0 5.5e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 RUS73921.1 - 4.1e-20 72.0 0.0 9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS73921.1 - 1.4e-16 60.7 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 RUS73921.1 - 0.00036 20.3 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain T-box PF00907.22 RUS73922.1 - 4.4e-73 245.5 0.0 5.6e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 T-box Fibrinogen_C PF00147.18 RUS73925.1 - 3.9e-61 206.7 6.3 5.6e-61 206.2 6.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain NPA PF16469.5 RUS73925.1 - 0.038 14.6 0.2 0.079 13.5 0.2 1.5 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Occludin_ELL PF07303.13 RUS73925.1 - 0.062 14.0 0.8 2.5 8.9 0.3 2.3 1 1 1 2 2 2 0 Occludin homology domain DUF4446 PF14584.6 RUS73925.1 - 0.16 11.9 1.1 0.42 10.6 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) RGS PF00615.19 RUS73926.1 - 3.7e-28 98.2 0.4 5.5e-09 36.3 0.0 3.1 3 0 0 3 3 3 3 Regulator of G protein signaling domain MatP PF06303.12 RUS73927.1 - 0.00053 20.5 7.0 3 8.5 0.2 4.7 1 1 3 5 5 5 3 MatP N-terminal domain NosD PF05048.13 RUS73927.1 - 0.018 14.3 6.7 0.027 13.7 6.7 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Nebulin PF00880.18 RUS73927.1 - 0.082 12.8 4.1 2.6e+02 1.7 0.0 6.1 7 0 0 7 7 7 0 Nebulin repeat RecA_dep_nuc PF16786.5 RUS73927.1 - 0.42 10.8 7.8 3.6 7.8 1.5 2.8 1 1 1 2 2 2 0 Recombination enhancement, RecA-dependent nuclease SPRR2 PF14820.6 RUS73927.1 - 1.5 9.0 3.9 49 4.1 0.1 3.2 1 1 3 4 4 4 0 Small proline-rich 2 Sec31 PF11549.8 RUS73928.1 - 0.0022 17.9 0.4 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein transport protein SEC31 DUF5343 PF17278.2 RUS73928.1 - 0.0039 17.3 0.7 0.62 10.1 0.0 2.5 2 1 0 2 2 2 2 Family of unknown function (DUF5343) DUF4375 PF14300.6 RUS73928.1 - 0.012 15.8 0.0 0.79 10.0 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) LIM PF00412.22 RUS73929.1 - 3e-33 113.8 32.1 3.2e-13 49.7 4.7 3.5 3 1 0 3 3 3 3 LIM domain C2 PF00168.30 RUS73930.1 - 5.4e-20 71.6 0.5 3.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 C2 domain PH PF00169.29 RUS73933.1 - 0.00094 19.7 0.0 0.0015 19.0 0.0 1.2 1 0 0 1 1 1 1 PH domain PH PF00169.29 RUS73934.1 - 6.4e-11 42.7 3.7 2.3e-07 31.3 0.0 4.2 4 0 0 4 4 4 2 PH domain CBM_14 PF01607.24 RUS73936.1 - 3e-06 27.3 2.9 6.3e-06 26.3 2.9 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DHC_N2 PF08393.13 RUS73939.1 - 1e-87 294.9 4.6 1e-87 294.9 4.6 1.6 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Sulfotransfer_2 PF03567.14 RUS73939.1 - 4.8e-23 82.4 0.1 1.2e-22 81.0 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family CCDC154 PF15450.6 RUS73939.1 - 0.016 13.8 1.7 1 7.8 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 DUF2848 PF11010.8 RUS73939.1 - 0.047 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) UQ_con PF00179.26 RUS73940.1 - 5.5e-26 90.9 0.0 3.4e-17 62.4 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme MA3 PF02847.17 RUS73941.1 - 3.1e-24 85.1 1.7 5.3e-24 84.4 1.7 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RUS73941.1 - 4.2e-05 23.3 6.3 0.00016 21.4 0.8 2.8 2 1 0 2 2 2 2 MIF4G domain LMBR1 PF04791.16 RUS73942.1 - 0.78 8.6 6.5 0.86 8.4 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NPR3 PF03666.13 RUS73942.1 - 0.78 8.5 12.0 1.1 7.9 12.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 RUS73942.1 - 1.5 7.3 19.1 1.8 7.0 19.1 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 RUS73942.1 - 1.5 7.9 5.6 2 7.5 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 RUS73942.1 - 2.9 6.5 8.5 3.7 6.2 8.5 1.1 1 0 0 1 1 1 0 Raftlin PNISR PF15996.5 RUS73942.1 - 4.6 7.5 10.0 6.6 6.9 10.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4407 PF14362.6 RUS73942.1 - 6.3 6.0 5.7 8.8 5.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 RUS73942.1 - 6.4 6.2 13.2 1.7 8.1 10.5 1.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.6 RUS73942.1 - 8.2 5.1 9.8 14 4.4 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Opacity PF02462.15 RUS73943.1 - 0.0015 18.6 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 Opacity family porin protein EphA2_TM PF14575.6 RUS73943.1 - 0.057 14.3 0.7 0.15 13.0 0.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS73943.1 - 0.24 11.6 2.1 0.48 10.6 2.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator R3H PF01424.22 RUS73944.1 - 9.7e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 R3H domain CENP-H PF05837.12 RUS73944.1 - 0.0021 18.4 1.9 0.0035 17.7 1.9 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF5560 PF17715.1 RUS73946.1 - 0.14 11.6 11.1 0.077 12.4 9.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5560) Trypsin_2 PF13365.6 RUS73947.1 - 0.00071 20.5 0.0 0.002 19.0 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Chlorophyllase2 PF12740.7 RUS73947.1 - 0.74 8.7 2.0 6.2 5.6 0.1 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Tmemb_185A PF10269.9 RUS73949.1 - 1.2e-53 182.4 23.9 1.8e-53 181.8 23.9 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein TPR_MLP1_2 PF07926.12 RUS73951.1 - 0.0049 16.9 23.5 0.22 11.6 7.7 3.2 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein HALZ PF02183.18 RUS73951.1 - 0.06 13.6 14.6 0.11 12.7 3.1 4.4 4 1 1 5 5 5 0 Homeobox associated leucine zipper CENP-H PF05837.12 RUS73951.1 - 0.18 12.2 22.3 0.056 13.9 2.3 3.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 RUS73951.1 - 0.19 11.1 12.3 0.28 10.5 6.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GLTSCR1 PF15249.6 RUS73951.1 - 0.25 11.8 9.8 0.45 11.0 1.4 2.9 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein FapA PF03961.13 RUS73951.1 - 0.28 9.8 9.7 0.78 8.3 1.6 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 RUS73951.1 - 1.3 9.6 29.9 2.6 8.6 5.5 3.3 2 2 1 3 3 3 0 Apg6 coiled-coil region Neur_chan_memb PF02932.16 RUS73951.1 - 1.9 8.5 7.7 0.17 11.9 1.7 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF948 PF06103.11 RUS73951.1 - 2 8.7 4.6 7.8 6.8 0.1 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) NYD-SP28_assoc PF14775.6 RUS73951.1 - 3.6 7.8 11.8 0.24 11.5 1.8 3.2 3 1 0 3 3 3 0 Sperm tail C-terminal domain SAM_2 PF07647.17 RUS73952.1 - 1.5e-16 60.2 1.3 1.1e-09 38.3 0.0 3.5 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS73952.1 - 1.1e-11 45.0 0.8 9.9e-06 25.9 0.1 3.4 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) FxsA PF04186.13 RUS73952.1 - 0.22 11.7 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein FAM181 PF15238.6 RUS73953.1 - 0.19 11.6 9.1 0.039 13.8 2.4 2.1 1 1 1 2 2 2 0 FAM181 DUF778 PF05608.12 RUS73954.1 - 2.1e-44 152.1 8.0 4.5e-24 85.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Folate_rec PF03024.14 RUS73955.1 - 4.9e-16 59.1 9.8 7e-16 58.6 9.8 1.2 1 0 0 1 1 1 1 Folate receptor family DUF3523 PF12037.8 RUS73956.1 - 7.8e-75 251.7 30.9 9.2e-75 251.4 30.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF966 PF06136.13 RUS73956.1 - 8.1 6.1 19.1 10 5.7 19.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Swi3 PF07962.12 RUS73957.1 - 2.3e-30 104.4 0.2 6e-30 103.1 0.2 1.8 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RNase_P_p30 PF01876.16 RUS73958.1 - 1.1e-58 198.3 0.0 1.1e-58 198.3 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit p30 Sporozoite_P67 PF05642.11 RUS73958.1 - 0.0012 17.1 5.2 0.0015 16.8 5.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.14 RUS73958.1 - 0.012 14.0 7.0 0.016 13.5 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TT_ORF2 PF02957.15 RUS73958.1 - 0.036 15.0 5.3 0.065 14.2 5.3 1.3 1 0 0 1 1 1 0 TT viral ORF2 TLP-20 PF06088.11 RUS73958.1 - 0.054 13.4 5.7 0.09 12.7 5.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RXT2_N PF08595.11 RUS73958.1 - 0.097 12.7 8.8 0.18 11.8 8.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 RUS73958.1 - 1.1 8.5 10.3 1.6 8.1 10.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 RUS73958.1 - 1.9 8.9 10.5 3.7 8.0 10.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 RUS73958.1 - 2.9 7.6 10.5 5.1 6.8 10.5 1.3 1 0 0 1 1 1 0 FAM176 family TFB6 PF17110.5 RUS73958.1 - 3.2 7.5 6.7 4.7 6.9 6.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF913 PF06025.12 RUS73958.1 - 6.9 5.5 7.6 10 5.0 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4611 PF15387.6 RUS73958.1 - 7.9 6.8 12.2 15 5.9 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 RUS73958.1 - 9 4.3 18.0 12 3.8 18.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF445 PF04286.12 RUS73959.1 - 0.001 19.0 0.8 0.0018 18.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) bZIP_1 PF00170.21 RUS73959.1 - 0.014 15.4 5.3 0.041 14.0 5.3 1.8 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 RUS73959.1 - 0.07 13.2 3.9 0.17 12.0 3.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper SLBP_RNA_bind PF15247.6 RUS73960.1 - 7.6e-25 86.8 4.8 7.6e-25 86.8 4.8 2.4 3 0 0 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain Rhodanese PF00581.20 RUS73961.1 - 6.7e-12 45.9 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-RING_2 PF13639.6 RUS73962.1 - 2.2e-13 50.3 10.2 8e-13 48.5 10.2 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RUS73962.1 - 1.2e-08 35.1 9.0 1.2e-08 35.1 9.0 3.2 4 0 0 4 4 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RUS73962.1 - 2.6e-08 33.4 6.2 2.6e-08 33.4 6.2 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS73962.1 - 6.1e-07 29.2 10.3 6.1e-07 29.2 10.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS73962.1 - 6.2e-07 29.2 9.7 1.2e-06 28.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS73962.1 - 8.2e-06 25.7 8.7 8.2e-06 25.7 8.7 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS73962.1 - 1.4e-05 24.8 7.6 2.7e-05 23.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS73962.1 - 5.5e-05 23.1 2.6 5.5e-05 23.1 2.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RUS73962.1 - 0.0003 20.8 6.5 0.0003 20.8 6.5 3.3 4 1 0 4 4 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RUS73962.1 - 0.0017 18.2 8.9 0.0022 17.8 7.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SR-25 PF10500.9 RUS73962.1 - 0.025 14.2 5.4 0.049 13.2 5.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zn_ribbon_17 PF17120.5 RUS73962.1 - 0.12 12.0 9.7 0.3 10.8 9.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RUS73962.1 - 0.24 11.6 7.5 0.92 9.7 7.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 RUS73962.1 - 0.27 11.4 9.5 0.63 10.2 9.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 RUS73962.1 - 9.8 6.1 11.5 61 3.5 10.3 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PNRC PF15365.6 RUS73964.1 - 1.2 9.0 5.1 4.2 7.3 5.1 2.0 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ras PF00071.22 RUS73965.1 - 2.5e-52 176.7 0.0 2.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS73965.1 - 4.8e-20 72.0 0.0 6.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RUS73965.1 - 2.3e-07 30.6 0.2 6.1e-07 29.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RUS73965.1 - 2.3e-07 30.4 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS73965.1 - 0.0043 17.1 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RUS73965.1 - 0.0053 16.6 0.8 0.029 14.2 0.1 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RUS73965.1 - 0.0072 16.3 0.7 2.8 7.8 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RUS73965.1 - 0.018 14.6 0.1 0.041 13.4 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 RUS73965.1 - 0.089 12.0 0.1 0.75 9.0 0.0 2.1 1 1 1 2 2 2 0 Septin AAA_16 PF13191.6 RUS73965.1 - 0.1 13.0 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ParA PF10609.9 RUS73965.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Ig_3 PF13927.6 RUS73966.1 - 1.1e-12 48.3 0.0 1.2e-08 35.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS73966.1 - 1.5e-10 41.0 0.0 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS73966.1 - 1.5e-09 37.9 0.2 3.8e-05 23.8 0.0 2.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS73966.1 - 2e-08 34.4 0.0 0.00039 20.6 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS73966.1 - 4.1e-05 23.8 0.0 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 RUS73966.1 - 6.1e-05 23.2 0.0 0.14 12.5 0.0 3.3 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS73966.1 - 0.00033 20.2 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gp2 PF05955.11 RUS73966.1 - 0.019 14.5 0.1 0.038 13.5 0.1 1.5 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Izumo-Ig PF16706.5 RUS73966.1 - 0.025 14.6 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain FAM70 PF14967.6 RUS73967.1 - 0.5 9.8 2.5 1.1 8.7 2.5 1.5 1 0 0 1 1 1 0 FAM70 protein SMC_N PF02463.19 RUS73968.1 - 2.4e-61 207.0 27.8 3.1e-60 203.3 27.8 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RUS73968.1 - 3.4e-24 85.4 0.0 1.1e-23 83.8 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 RUS73968.1 - 3.3e-14 53.9 36.7 3.3e-14 53.9 36.7 7.2 4 2 2 6 6 6 1 AAA domain AAA_21 PF13304.6 RUS73968.1 - 1.2e-11 45.0 11.1 1e-07 32.1 0.1 3.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS73968.1 - 1.4e-08 34.3 0.0 3.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 RUS73968.1 - 1.4e-05 25.0 45.0 1.4e-05 25.0 45.0 4.8 3 2 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 RUS73968.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1482 PF07358.11 RUS73968.1 - 0.058 13.3 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) PhnA PF03831.14 RUS73968.1 - 0.072 13.0 0.1 2.1 8.3 0.1 2.8 1 1 2 3 3 3 0 PhnA domain AAA_22 PF13401.6 RUS73968.1 - 4.1 7.7 0.0 4.1 7.7 0.0 4.1 4 1 0 4 4 4 0 AAA domain DUF3969 PF13108.6 RUS73969.1 - 9.6e-09 35.2 2.8 32 4.6 0.0 6.6 1 1 9 10 10 10 2 Protein of unknown function (DUF3969) USP7_ICP0_bdg PF12436.8 RUS73969.1 - 6.8e-06 25.6 2.5 15 4.8 0.0 5.9 1 1 6 7 7 7 3 ICP0-binding domain of Ubiquitin-specific protease 7 DUF5579 PF17742.1 RUS73969.1 - 0.86 9.1 17.8 39 3.7 0.4 5.7 1 1 7 8 8 8 0 Family of unknown function (DUF5579) DUF3969 PF13108.6 RUS73970.1 - 4.8e-11 42.6 5.4 49 4.0 0.0 8.7 1 1 8 10 10 10 4 Protein of unknown function (DUF3969) DUF5579 PF17742.1 RUS73970.1 - 2.7 7.5 25.2 67 3.0 0.7 7.4 1 1 8 10 10 10 0 Family of unknown function (DUF5579) RIB43A PF05914.12 RUS73971.1 - 1.6e-143 478.0 58.3 1.8e-143 477.9 58.3 1.0 1 0 0 1 1 1 1 RIB43A CheX PF13690.6 RUS73971.1 - 0.0028 17.8 0.4 0.11 12.6 0.1 2.7 2 0 0 2 2 2 1 Chemotaxis phosphatase CheX Kinesin PF00225.23 RUS73972.1 - 1.4e-109 366.1 0.0 3e-109 365.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS73972.1 - 5.7e-23 81.5 0.0 2e-22 79.7 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding DUF3519 PF12033.8 RUS73972.1 - 0.057 13.8 1.9 0.15 12.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) MamL-1 PF09596.10 RUS73972.1 - 0.059 13.6 5.1 8.9 6.6 0.4 3.9 3 0 0 3 3 3 0 MamL-1 domain Mit_KHE1 PF10173.9 RUS73972.1 - 0.15 12.1 3.0 0.41 10.7 3.0 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Zeta_toxin PF06414.12 RUS73972.1 - 0.16 11.2 4.1 1.9 7.7 3.2 2.4 2 0 0 2 2 2 0 Zeta toxin RabGAP-TBC PF00566.18 RUS73973.1 - 3.3e-10 40.0 5.1 2.1e-09 37.4 2.2 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain YqjK PF13997.6 RUS73973.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 YqjK-like protein IL4_i_Ig PF18258.1 RUS73974.1 - 0.02 15.1 0.1 0.13 12.5 0.0 2.2 1 1 1 2 2 2 0 Interleukin-4 inducing immunoglobulin-binding domain ApoC-I PF04691.12 RUS73975.1 - 0.13 12.2 2.1 88 3.1 0.0 4.0 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) Fanconi_A PF03511.14 RUS73976.1 - 0.12 12.3 2.2 7.1 6.6 0.1 3.1 3 0 0 3 3 3 0 Fanconi anaemia group A protein DUF4504 PF14953.6 RUS73977.1 - 1.9e-23 83.2 4.3 6.8e-22 78.1 4.3 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) EF-hand_6 PF13405.6 RUS73978.1 - 1e-06 28.2 0.6 0.02 14.8 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS73978.1 - 9.4e-06 26.0 2.1 9.4e-06 26.0 2.1 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS73978.1 - 0.0034 16.8 2.0 0.0046 16.4 0.1 2.3 2 0 0 2 2 2 1 EF hand Extensin_2 PF04554.13 RUS73978.1 - 1.8 8.7 25.2 5.4 7.2 25.1 1.9 1 1 0 1 1 1 0 Extensin-like region APH PF01636.23 RUS73979.1 - 4.4e-07 30.1 0.0 6.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.26 RUS73980.1 - 2.3e-26 91.4 0.1 2.7e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 RUS73980.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 RUS73980.1 - 0.0023 18.0 0.1 0.0027 17.8 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PP2C PF00481.21 RUS73982.1 - 6.1e-39 134.2 0.1 3.9e-37 128.3 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RUS73982.1 - 8.9e-05 22.5 0.2 0.002 18.1 0.2 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RUS73982.1 - 0.0084 15.8 0.0 0.13 11.9 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C p450 PF00067.22 RUS73984.1 - 2.1e-86 290.5 0.1 2.9e-68 230.7 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 PHD PF00628.29 RUS73985.1 - 1.5e-07 31.2 4.9 2e-07 30.8 3.4 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RUS73985.1 - 3.8e-05 23.1 2.6 0.0001 21.7 2.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RUS73985.1 - 0.00024 20.9 1.7 0.00075 19.3 1.7 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RUS73985.1 - 0.0075 16.6 2.3 0.041 14.2 0.7 2.4 2 0 0 2 2 2 1 C1 domain AT_hook PF02178.19 RUS73985.1 - 0.04 13.8 2.0 0.15 12.0 2.0 2.0 1 0 0 1 1 1 0 AT hook motif zf-UDP PF14569.6 RUS73985.1 - 0.13 12.4 1.1 0.63 10.2 1.4 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger FYVE_2 PF02318.16 RUS73985.1 - 2.1 8.6 7.4 0.11 12.8 1.1 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger PARG_cat PF05028.14 RUS73986.1 - 2.1e-133 444.8 0.0 2.8e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DEAD PF00270.29 RUS73987.1 - 2e-46 157.9 0.3 9.3e-46 155.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS73987.1 - 7.5e-27 93.9 0.0 1.3e-25 89.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS73987.1 - 2.1e-05 24.6 0.0 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CdAMP_rec PF06153.11 RUS73987.1 - 0.032 14.4 0.3 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Cyclic-di-AMP receptor SR-25 PF10500.9 RUS73987.1 - 0.81 9.3 39.3 1.6 8.3 39.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gar1 PF04410.14 RUS73988.1 - 2.3e-38 131.4 0.0 3.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Fringe PF02434.16 RUS73990.1 - 2.2e-08 33.9 3.4 2.8e-07 30.2 3.3 2.4 1 1 1 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 RUS73990.1 - 1.2e-05 25.2 0.0 0.033 14.0 0.1 2.2 1 1 1 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 RUS73990.1 - 0.014 15.3 0.7 0.18 11.7 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase family group 2 Lig_chan-Glu_bd PF10613.9 RUS73991.1 - 9.7e-20 70.9 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS73991.1 - 0.0016 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ARD PF03079.14 RUS73992.1 - 8e-46 156.1 0.4 1e-45 155.7 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS73992.1 - 2e-06 27.4 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS73992.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain PPP1R32 PF15691.5 RUS73992.1 - 0.048 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 32 Cupin_6 PF12852.7 RUS73992.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.7 1 1 1 2 2 2 0 Cupin BTB PF00651.31 RUS73994.1 - 2.4e-23 82.5 0.8 2.8e-22 79.1 0.1 2.5 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 RUS73994.1 - 1e-15 57.6 0.6 7.2e-15 55.0 0.7 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch TraH PF06122.11 RUS73994.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein baeRF_family6 PF18848.1 RUS73994.1 - 0.034 14.6 0.4 61 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 6 BTB PF00651.31 RUS73995.1 - 7.5e-24 84.1 3.5 9.3e-24 83.8 1.3 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS73995.1 - 2.5e-15 56.4 1.5 3.1e-14 52.9 0.6 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Peptidase_M1 PF01433.20 RUS73996.1 - 5.4e-19 68.6 0.0 1.8e-18 66.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RUS73996.1 - 3.7e-10 39.9 0.1 6.8e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RUS73996.1 - 0.00078 19.7 0.3 0.0025 18.0 0.3 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 RUS73996.1 - 0.0038 17.6 0.8 0.074 13.5 0.8 2.7 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Trans_reg_C PF00486.28 RUS73998.1 - 0.078 13.1 0.1 17 5.6 0.1 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal DivIC PF04977.15 RUS74001.1 - 0.022 14.5 4.1 0.022 14.5 4.1 3.4 1 1 2 3 3 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 RUS74001.1 - 0.097 12.2 12.0 0.13 11.8 12.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 RUS74001.1 - 0.29 10.4 21.4 0.013 14.9 8.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 RUS74001.1 - 0.45 9.3 14.5 0.043 12.7 9.8 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.10 RUS74001.1 - 1.8 8.8 13.3 4 7.6 9.0 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 RUS74001.1 - 4.6 7.6 14.4 0.34 11.2 7.4 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 RUS74001.1 - 9.6 5.6 19.4 0.68 9.3 8.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 RUS74002.1 - 0.00059 18.8 13.6 0.00076 18.5 1.9 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein ATG16 PF08614.11 RUS74002.1 - 0.0012 19.1 3.0 0.0012 19.1 3.0 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.6 RUS74002.1 - 0.0017 17.7 11.6 0.012 15.0 1.4 2.5 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 RUS74002.1 - 0.0022 17.8 6.5 0.17 11.6 0.2 2.1 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tropomyosin_1 PF12718.7 RUS74002.1 - 0.0023 18.1 1.3 0.0023 18.1 1.3 2.3 2 0 0 2 2 2 1 Tropomyosin like TMF_DNA_bd PF12329.8 RUS74002.1 - 0.0063 16.5 4.7 0.0063 16.5 4.7 2.7 3 1 0 3 3 2 1 TATA element modulatory factor 1 DNA binding IFT57 PF10498.9 RUS74002.1 - 0.0086 15.1 4.6 0.17 10.8 0.5 2.1 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Flagellin_C PF00700.21 RUS74002.1 - 0.011 16.1 0.4 2.6 8.5 0.0 2.9 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region Filament PF00038.21 RUS74002.1 - 0.011 15.3 2.1 0.011 15.3 2.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein GCN5L1 PF06320.13 RUS74002.1 - 0.019 15.1 0.7 5.9 7.1 0.1 2.6 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) SseC PF04888.12 RUS74002.1 - 0.024 14.2 1.9 0.14 11.7 0.4 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Mod_r PF07200.13 RUS74002.1 - 0.03 14.4 8.4 0.85 9.7 1.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 RUS74002.1 - 0.037 14.0 17.8 0.052 13.6 4.6 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 RUS74002.1 - 0.038 13.8 6.7 0.27 11.0 0.7 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3584 PF12128.8 RUS74002.1 - 0.046 11.2 9.7 0.088 10.3 9.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 RUS74002.1 - 0.056 13.5 3.9 2.8 8.0 0.2 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 RUS74002.1 - 0.096 11.3 4.8 0.13 10.9 0.2 2.1 1 1 1 2 2 2 0 AAA domain Sec8_exocyst PF04048.14 RUS74002.1 - 0.11 12.4 1.9 8.9 6.2 0.4 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF4890 PF16231.5 RUS74002.1 - 0.11 13.0 8.2 0.13 12.8 3.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) TMPIT PF07851.13 RUS74002.1 - 0.12 11.6 4.5 2.6 7.2 0.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein Suppressor_APC PF11414.8 RUS74002.1 - 0.14 12.2 4.1 0.072 13.2 0.9 2.2 2 1 1 3 3 2 0 Adenomatous polyposis coli tumour suppressor protein CENP-H PF05837.12 RUS74002.1 - 0.14 12.5 11.7 1.6 9.2 1.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LPP PF04728.13 RUS74002.1 - 0.15 12.4 1.4 1.6 9.2 0.0 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Leu_zip PF15294.6 RUS74002.1 - 0.17 11.4 8.7 0.078 12.5 5.5 1.7 1 1 1 2 2 2 0 Leucine zipper CCDC144C PF14915.6 RUS74002.1 - 0.17 10.9 11.9 0.38 9.8 11.9 1.6 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region TMF_TATA_bd PF12325.8 RUS74002.1 - 0.17 12.1 14.4 0.84 9.9 1.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.13 RUS74002.1 - 0.19 11.8 5.9 7.5 6.6 2.0 2.5 2 1 0 2 2 2 0 DivIVA protein Atg14 PF10186.9 RUS74002.1 - 0.2 10.7 13.2 0.089 11.9 2.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 RUS74002.1 - 0.2 10.9 7.0 0.17 11.1 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APC1_C PF18122.1 RUS74002.1 - 0.21 11.5 1.1 3.4 7.6 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Snapin_Pallidin PF14712.6 RUS74002.1 - 0.23 11.9 8.3 1.1 9.7 0.3 3.1 2 1 1 3 3 3 0 Snapin/Pallidin PI3K_P85_iSH2 PF16454.5 RUS74002.1 - 0.24 11.0 8.2 1 8.9 0.7 2.4 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 RUS74002.1 - 0.27 11.3 12.3 0.13 12.3 1.7 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 RUS74002.1 - 0.31 11.5 15.1 0.74 10.2 15.1 1.6 1 1 0 1 1 1 0 Fez1 Fungal_TACC PF12709.7 RUS74002.1 - 0.31 11.5 3.2 4.6 7.8 0.2 2.8 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Seryl_tRNA_N PF02403.22 RUS74002.1 - 0.37 11.0 7.1 3.5 7.9 0.2 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HMMR_C PF15908.5 RUS74002.1 - 0.39 11.0 5.8 9.9 6.4 1.1 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal FapA PF03961.13 RUS74002.1 - 0.39 9.3 4.8 1.5 7.3 4.8 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 RUS74002.1 - 0.49 10.6 14.2 3.2 7.9 14.2 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4600 PF15372.6 RUS74002.1 - 0.6 10.5 7.5 1.7 9.1 6.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Tup_N PF08581.10 RUS74002.1 - 0.7 10.2 9.8 1.4 9.3 0.4 2.6 2 1 0 2 2 2 0 Tup N-terminal Rho_Binding PF08912.11 RUS74002.1 - 0.74 10.7 11.1 3.6 8.5 0.7 3.0 2 1 1 3 3 3 0 Rho Binding KASH_CCD PF14662.6 RUS74002.1 - 0.83 9.4 13.3 7 6.4 13.3 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 RUS74002.1 - 1.1 10.0 9.9 8.8 7.0 0.5 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Bcr-Abl_Oligo PF09036.10 RUS74002.1 - 1.1 9.3 6.3 0.32 11.0 0.5 2.9 2 2 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF4201 PF13870.6 RUS74002.1 - 1.1 8.9 13.3 3.9 7.2 8.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2408 PF10303.9 RUS74002.1 - 1.2 9.7 9.0 3.7 8.1 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HAUS6_N PF14661.6 RUS74002.1 - 1.5 8.4 9.2 0.71 9.4 3.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.19 RUS74002.1 - 1.5 6.7 4.3 1.8 6.4 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RUS74002.1 - 1.6 9.2 16.2 6.7 7.3 12.4 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Prefoldin PF02996.17 RUS74002.1 - 1.7 8.6 7.5 1.8 8.5 3.3 2.7 2 1 0 2 2 1 0 Prefoldin subunit CENP-Q PF13094.6 RUS74002.1 - 2.5 8.3 15.3 31 4.7 15.3 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BST2 PF16716.5 RUS74002.1 - 2.5 8.7 10.6 0.17 12.5 0.9 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 YgaB PF14182.6 RUS74002.1 - 3.3 8.2 13.0 0.51 10.8 1.8 3.1 3 1 0 3 3 3 0 YgaB-like protein DivIC PF04977.15 RUS74002.1 - 4.1 7.3 10.9 12 5.7 2.0 3.2 1 1 3 4 4 4 0 Septum formation initiator ZapB PF06005.12 RUS74002.1 - 5.2 7.6 13.5 2 8.9 1.7 2.8 2 1 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 RUS74002.1 - 6.4 7.7 16.7 7.9 7.4 5.5 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain LMBR1 PF04791.16 RUS74002.1 - 7.3 5.4 8.4 28 3.4 8.4 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein Spc24 PF08286.11 RUS74002.1 - 9.5 6.5 8.4 7.8 6.8 0.6 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3112 PF11309.8 RUS74003.1 - 2.5 7.5 4.3 5.6 6.3 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) LRR_8 PF13855.6 RUS74005.1 - 4.5e-18 64.8 39.1 7.3e-09 35.3 10.4 4.0 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 RUS74005.1 - 8.4e-14 51.5 22.6 0.00012 22.4 7.1 4.7 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS74005.1 - 1.2e-11 43.4 18.9 0.11 13.1 0.1 6.7 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_5 PF13306.6 RUS74005.1 - 0.013 15.4 0.9 0.03 14.3 0.7 1.8 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS74005.1 - 0.03 14.4 30.8 2.3 8.5 0.3 6.0 7 0 0 7 7 7 0 Leucine Rich repeat Homeodomain PF00046.29 RUS74007.1 - 1.5e-16 60.0 0.7 2.2e-16 59.4 0.7 1.3 1 0 0 1 1 1 1 Homeodomain Nop14 PF04147.12 RUS74007.1 - 0.017 13.4 10.3 0.019 13.2 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.12 RUS74007.1 - 0.022 12.8 7.1 0.025 12.6 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SDA1 PF05285.12 RUS74007.1 - 0.046 13.2 12.9 0.053 12.9 12.9 1.1 1 0 0 1 1 1 0 SDA1 Homez PF11569.8 RUS74007.1 - 0.055 12.9 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CDC45 PF02724.14 RUS74007.1 - 0.18 10.0 10.8 0.21 9.8 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 RUS74007.1 - 0.29 10.9 13.0 0.53 10.0 13.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Lectin_C PF00059.21 RUS74009.1 - 8.1e-10 39.4 0.2 1.7e-09 38.4 0.0 1.6 1 1 1 2 2 2 1 Lectin C-type domain Guanylate_cyc PF00211.20 RUS74011.1 - 1.7e-66 223.3 0.0 4.2e-65 218.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS74011.1 - 0.0004 19.9 0.8 0.0006 19.3 0.8 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.17 RUS74011.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ODR4-like PF14778.6 RUS74011.1 - 0.066 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like Na_Pi_cotrans PF02690.15 RUS74012.1 - 1.2e-35 122.6 22.2 1.3e-21 77.2 4.4 2.6 2 1 0 2 2 2 2 Na+/Pi-cotransporter Trypsin PF00089.26 RUS74013.1 - 1.9e-21 76.9 0.0 2.6e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RUS74013.1 - 0.034 14.5 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sel1 PF08238.12 RUS74014.1 - 2.5e-11 43.8 4.9 1.3e-09 38.4 0.1 2.8 3 0 0 3 3 3 2 Sel1 repeat Robl_LC7 PF03259.17 RUS74015.1 - 2.9e-24 84.7 0.0 3.2e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 RUS74015.1 - 3e-05 23.9 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 RUS74015.1 - 0.093 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain PNP_UDP_1 PF01048.20 RUS74016.1 - 1e-25 90.4 0.0 1.3e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SMC_ScpA PF02616.14 RUS74017.1 - 0.067 13.1 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Acyl-CoA_dh_1 PF00441.24 RUS74018.1 - 1.4e-39 135.7 0.2 2.3e-39 135.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS74018.1 - 1.1e-26 93.7 0.0 2.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RUS74018.1 - 3.2e-20 72.1 0.1 6.3e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RUS74018.1 - 3.1e-11 43.7 0.0 5.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RUS74018.1 - 0.07 12.8 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PH PF00169.29 RUS74020.1 - 9.8e-07 29.2 1.0 2e-06 28.3 1.0 1.5 1 0 0 1 1 1 1 PH domain Trypsin_2 PF13365.6 RUS74021.1 - 0.00013 22.9 0.1 0.00023 22.1 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RUS74021.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Trypsin ERF PF04404.12 RUS74021.1 - 0.12 12.2 0.4 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 ERF superfamily DUF3011 PF11218.8 RUS74023.1 - 6.4e-11 42.6 2.2 6.6e-11 42.6 1.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3011) RRM_1 PF00076.22 RUS74025.1 - 2.9e-36 123.1 0.4 3e-17 62.2 0.5 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS74025.1 - 1.1e-10 41.5 0.3 0.00031 20.8 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 RUS74025.1 - 1.3e-05 25.2 1.1 2.7e-05 24.2 1.1 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 RUS74025.1 - 0.0004 20.0 0.1 0.00061 19.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS74025.1 - 0.0017 18.2 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 RUS74025.1 - 0.0043 17.0 0.1 0.84 9.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif FYRC PF05965.14 RUS74026.1 - 1.1e-21 76.8 0.0 4.1e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus SET PF00856.28 RUS74026.1 - 1.8e-19 70.8 1.1 3.9e-19 69.7 0.2 2.2 2 0 0 2 2 2 1 SET domain FYRN PF05964.14 RUS74026.1 - 7.3e-19 67.4 1.7 1.4e-18 66.4 1.7 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H_2 PF13832.6 RUS74026.1 - 3.4e-11 43.3 6.0 9.3e-11 41.9 6.0 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RUS74026.1 - 3.6e-11 43.2 6.1 3.6e-11 43.2 6.1 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain cNMP_binding PF00027.29 RUS74029.1 - 1.2e-15 57.3 0.2 1.3e-13 50.8 0.1 2.9 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain Peptidase_S66 PF02016.15 RUS74029.1 - 0.034 14.3 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain CoaE PF01121.20 RUS74030.1 - 2.9e-47 160.6 0.1 7.3e-47 159.3 0.1 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 RUS74030.1 - 4.6e-06 26.9 0.1 1.2e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like VPS11_C PF12451.8 RUS74031.1 - 2.6e-19 69.2 0.4 7.4e-19 67.7 0.4 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 RUS74031.1 - 2.7e-18 66.2 21.1 8.8e-14 51.6 5.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 RUS74031.1 - 1.1e-05 25.2 10.2 3.2e-05 23.7 10.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS74031.1 - 0.00044 20.5 9.8 0.00044 20.5 9.8 1.9 2 0 0 2 2 2 1 Ring finger domain Vps39_2 PF10367.9 RUS74031.1 - 0.016 15.6 8.6 0.064 13.7 2.6 3.2 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 RUS74031.1 - 0.071 13.2 11.1 0.18 11.9 11.1 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_5 PF14634.6 RUS74031.1 - 0.18 11.8 9.4 0.47 10.4 9.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 RUS74031.1 - 0.35 11.2 11.4 0.29 11.5 8.5 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS74031.1 - 0.36 10.7 10.2 0.98 9.3 10.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 RUS74031.1 - 2.4 8.6 9.8 1.7 9.0 6.4 2.3 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_3 PF13920.6 RUS74031.1 - 2.6 8.0 6.2 6 6.8 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RUS74031.1 - 5.1 6.8 6.4 14 5.4 6.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Phasin_2 PF09361.10 RUS74032.1 - 2.8e-06 27.5 0.7 0.0014 18.8 0.1 3.0 1 1 1 2 2 2 2 Phasin protein DUF948 PF06103.11 RUS74032.1 - 0.0055 16.9 3.5 1.2 9.4 0.3 3.0 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) RRF PF01765.19 RUS74032.1 - 0.0076 16.2 4.3 0.0076 16.2 4.3 1.8 2 0 0 2 2 2 1 Ribosome recycling factor ApoLp-III PF07464.11 RUS74032.1 - 0.025 14.7 7.2 0.25 11.4 7.2 2.1 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Senescence PF06911.12 RUS74032.1 - 0.033 14.5 9.2 0.6 10.4 1.9 2.5 1 1 1 2 2 2 0 Senescence-associated protein PMC2NT PF08066.12 RUS74032.1 - 0.046 14.4 0.4 0.15 12.7 0.3 1.8 2 0 0 2 2 2 0 PMC2NT (NUC016) domain BAR PF03114.18 RUS74032.1 - 0.077 12.6 2.2 0.1 12.2 2.2 1.1 1 0 0 1 1 1 0 BAR domain DUF883 PF05957.13 RUS74032.1 - 0.079 13.6 1.3 0.67 10.6 0.1 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TMP_2 PF06791.13 RUS74032.1 - 0.088 12.5 2.6 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein MCPsignal PF00015.21 RUS74032.1 - 0.11 12.3 4.0 0.19 11.5 1.2 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EspB PF05802.11 RUS74032.1 - 0.2 11.7 6.0 1.2 9.1 6.0 2.2 1 1 0 1 1 1 0 Enterobacterial EspB protein ERp29 PF07749.12 RUS74032.1 - 0.74 10.8 5.9 0.32 11.9 1.2 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Phasin PF05597.11 RUS74032.1 - 0.76 9.8 6.3 1.3 9.0 0.7 2.6 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 RUS74032.1 - 2 9.0 14.2 8e+02 0.7 13.6 3.2 2 1 0 2 2 1 0 YtxH-like protein Ephrin_rec_like PF07699.13 RUS74033.1 - 2.3e-07 30.5 0.8 2.3e-07 30.5 0.8 2.5 2 1 1 3 3 3 2 Putative ephrin-receptor like TNFR_c6 PF00020.18 RUS74033.1 - 0.27 11.7 0.3 0.27 11.7 0.3 3.1 2 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 RUS74033.1 - 1.3 9.1 8.2 0.13 12.2 1.9 2.4 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR 7tm_1 PF00001.21 RUS74035.1 - 2.6e-38 131.9 12.5 3.3e-38 131.5 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS74035.1 - 0.00034 20.1 23.9 0.0037 16.7 23.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Myc_N PF01056.18 RUS74035.1 - 0.082 12.8 0.5 0.12 12.3 0.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region AAA_19 PF13245.6 RUS74036.1 - 5.1e-05 23.7 0.1 0.094 13.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 RUS74036.1 - 0.00014 21.7 0.5 0.39 10.5 0.0 2.8 2 1 0 3 3 3 2 DEAD/DEAH box helicase DUF2075 PF09848.9 RUS74036.1 - 0.00026 20.3 0.0 0.00062 19.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RUS74036.1 - 0.00026 20.9 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 RUS74036.1 - 0.00028 20.9 0.2 0.16 12.0 0.0 4.0 3 1 1 4 4 4 1 AAA domain UvrD-helicase PF00580.21 RUS74036.1 - 0.00033 20.3 0.1 1.2 8.6 0.0 2.9 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 RUS74036.1 - 0.00055 19.8 2.7 0.0056 16.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 RUS74036.1 - 0.0008 19.7 0.3 0.048 13.9 0.1 3.1 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 RUS74036.1 - 0.0011 19.3 1.7 0.013 15.9 0.1 3.1 2 2 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 RUS74036.1 - 0.0011 18.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS74036.1 - 0.0017 18.8 0.2 0.02 15.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_12 PF13087.6 RUS74036.1 - 0.0047 16.6 1.1 0.0088 15.7 0.4 1.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 RUS74036.1 - 0.0051 16.6 0.0 0.017 15.0 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 RUS74036.1 - 0.0098 15.3 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_33 PF13671.6 RUS74036.1 - 0.011 15.9 0.0 0.14 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 RUS74036.1 - 0.011 15.7 0.7 0.097 12.7 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 RUS74036.1 - 0.03 13.7 0.1 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 RUS74036.1 - 0.044 13.0 0.3 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.29 RUS74036.1 - 0.052 14.0 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Carb_anhydrase PF00194.21 RUS74036.1 - 0.074 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Viral_helicase1 PF01443.18 RUS74036.1 - 0.076 12.7 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ig_3 PF13927.6 RUS74037.1 - 6.5e-19 68.3 0.5 1.5e-08 35.2 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS74037.1 - 4.3e-18 65.2 0.0 1.3e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS74037.1 - 7.7e-15 54.8 0.7 4e-06 26.9 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS74037.1 - 5.6e-12 45.8 0.2 6.4e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS74037.1 - 4.3e-11 43.0 0.8 3.5e-07 30.4 0.1 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS74037.1 - 6.4e-06 25.6 0.0 0.018 14.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 RUS74037.1 - 0.00018 21.8 0.1 0.0044 17.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 RUS74037.1 - 0.0005 20.4 0.5 0.041 14.3 0.1 3.3 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 RUS74037.1 - 0.0009 19.4 0.0 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 RUS74037.1 - 0.04 14.0 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Abhydrolase_3 PF07859.13 RUS74038.1 - 1.3e-37 129.7 0.0 1.7e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RUS74038.1 - 3.7e-06 26.1 0.3 1e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS74038.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS74038.1 - 0.0009 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase ASC PF00858.24 RUS74039.1 - 1.9e-22 79.9 0.5 2.2e-22 79.7 0.5 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SMN PF06003.12 RUS74041.1 - 9.7 5.4 8.5 15 4.8 8.5 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Homeodomain PF00046.29 RUS74043.1 - 7.4e-21 73.8 2.2 7.4e-21 73.8 2.2 1.7 2 0 0 2 2 2 1 Homeodomain DUF4718 PF15842.5 RUS74044.1 - 1.2 8.9 2.8 1.9 8.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Macoilin PF09726.9 RUS74044.1 - 9.8 4.6 13.4 15 4.0 13.4 1.3 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_4 PF13359.6 RUS74045.1 - 2e-36 125.1 0.0 2.8e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS74045.1 - 8.4e-10 38.6 0.0 4.2e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS74045.1 - 1.1e-08 35.1 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 RUS74045.1 - 0.022 15.1 0.2 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain HTH_23 PF13384.6 RUS74045.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Bac_A_amyl_C PF18612.1 RUS74048.1 - 6.2e-05 22.7 0.5 0.075 12.8 0.1 2.5 2 0 0 2 2 2 2 Bacterial Alpha amylase C-terminal domain TRP_2 PF08344.11 RUS74048.1 - 0.014 15.6 0.4 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Transient receptor ion channel II RNA_pol_Rpb5_C PF01191.19 RUS74048.1 - 0.029 14.2 0.1 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DRY_EERY PF09750.9 RUS74048.1 - 3.3 8.0 7.1 2.8 8.2 0.5 2.4 2 0 0 2 2 2 0 Alternative splicing regulator HTH_Tnp_IS1 PF12759.7 RUS74049.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Cbl_N PF02262.16 RUS74050.1 - 0.00045 20.2 0.3 0.65 10.0 0.0 2.4 2 0 0 2 2 2 2 CBL proto-oncogene N-terminal domain 1 Herpes_UL55 PF04537.12 RUS74050.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL55 protein FHA PF00498.26 RUS74051.1 - 1.2e-17 64.0 0.0 2.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 RUS74051.1 - 4.6e-09 36.0 9.6 4.6e-09 36.0 9.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS74051.1 - 2.3e-08 33.7 11.2 2.3e-08 33.7 11.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS74051.1 - 7.7e-08 32.6 10.3 1.6e-07 31.6 10.3 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 RUS74051.1 - 2.9e-07 30.7 0.6 2.1e-06 27.9 0.0 2.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 RUS74051.1 - 4e-07 29.8 12.8 9.2e-07 28.6 12.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS74051.1 - 4.5e-06 26.6 5.7 9.4e-06 25.6 5.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS74051.1 - 1.1e-05 25.4 9.6 2.6e-05 24.3 9.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RUS74051.1 - 3.4e-05 24.0 6.8 0.00011 22.4 6.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RUS74051.1 - 6.7e-05 22.9 6.4 0.00016 21.8 6.4 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 RUS74051.1 - 0.00029 20.8 11.0 0.00064 19.6 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS74051.1 - 0.00063 19.5 8.9 0.0013 18.5 8.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 RUS74051.1 - 0.0014 18.5 3.3 0.0033 17.3 2.9 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-CCHC PF00098.23 RUS74051.1 - 0.003 17.6 5.5 0.003 17.6 5.5 2.2 3 0 0 3 3 2 1 Zinc knuckle zf-RING_4 PF14570.6 RUS74051.1 - 0.0069 16.2 3.9 0.021 14.6 3.9 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 RUS74051.1 - 0.043 13.9 1.5 0.18 11.9 1.5 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-CCHC_4 PF14392.6 RUS74051.1 - 0.067 12.9 1.1 0.25 11.1 1.1 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 RUS74051.1 - 0.067 12.9 2.7 0.2 11.4 2.7 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-ANAPC11 PF12861.7 RUS74051.1 - 0.14 12.2 2.6 0.31 11.1 2.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2746 PF10874.8 RUS74051.1 - 1.4 9.4 4.1 1.1 9.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) zf-Nse PF11789.8 RUS74051.1 - 3.8 7.4 5.8 8.8 6.2 5.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-LITAF-like PF10601.9 RUS74051.1 - 4.2 7.7 8.8 15 5.9 8.8 2.0 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 RUS74051.1 - 9.9 5.7 8.8 22 4.6 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF4513 PF14983.6 RUS74052.1 - 3.1e-07 30.5 0.1 3.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4513) Sulf_transp PF04143.14 RUS74054.1 - 5.3e-38 131.3 30.9 8.1e-38 130.7 28.9 1.8 2 0 0 2 2 2 1 Sulphur transport AKNA PF12443.8 RUS74055.1 - 0.06 14.0 2.0 0.15 12.7 0.4 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor FlaC_arch PF05377.11 RUS74055.1 - 4.4 7.8 9.3 1.7 9.1 0.5 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 RUS74057.1 - 2.7e-61 207.2 0.0 4.7e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74057.1 - 1.7e-40 138.9 0.0 2.6e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS74057.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS74057.1 - 0.0022 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS74057.1 - 0.015 14.1 0.6 0.033 13.0 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RUS74057.1 - 0.019 14.9 0.3 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ustilago_mating PF05722.12 RUS74057.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein LRR_8 PF13855.6 RUS74058.1 - 1.3e-40 136.9 41.8 1.6e-09 37.4 1.7 8.1 5 3 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 RUS74058.1 - 5.5e-25 87.0 46.4 6e-06 26.5 1.4 10.0 6 3 5 11 11 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS74058.1 - 6.7e-12 45.5 0.2 0.0036 17.3 0.0 3.7 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS74058.1 - 5.3e-08 32.4 36.3 9.4 7.2 0.0 13.8 15 0 0 15 15 14 1 Leucine Rich Repeat Orf78 PF06024.12 RUS74058.1 - 0.00021 21.5 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) fn3 PF00041.21 RUS74058.1 - 0.00036 20.8 0.1 0.00079 19.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 RUS74058.1 - 0.00054 19.5 13.1 0.1 12.1 0.7 4.4 1 1 3 4 4 4 3 Leucine-rich repeat Insulin_TMD PF17870.1 RUS74058.1 - 0.00084 19.4 0.2 0.0018 18.3 0.2 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Mucin15 PF15672.5 RUS74058.1 - 0.0014 18.2 0.2 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 TMEM154 PF15102.6 RUS74058.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family PTP_tm PF18861.1 RUS74058.1 - 0.0019 18.2 0.1 0.0043 17.1 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 RUS74058.1 - 0.0031 17.4 0.3 0.0058 16.5 0.3 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Amnionless PF14828.6 RUS74058.1 - 0.072 11.9 0.1 0.26 10.1 0.0 1.8 1 1 1 2 2 2 0 Amnionless CD34_antigen PF06365.12 RUS74058.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 RUS74058.1 - 0.13 13.1 0.0 0.26 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_6 PF13516.6 RUS74058.1 - 0.3 11.3 29.5 9.2 6.6 0.3 9.7 12 0 0 12 12 9 0 Leucine Rich repeat Flagellar_put PF12611.8 RUS74058.1 - 1.2 9.0 2.9 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Putative flagellar ATG_C PF09333.11 RUS74059.1 - 3.9e-14 52.8 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 RUS74059.1 - 4.6e-12 46.1 0.0 1.5e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 RUS74059.1 - 1.3e-07 31.6 0.0 4.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 RUS74059.1 - 0.00072 19.3 0.2 0.0044 16.8 0.2 2.3 1 1 0 1 1 1 1 Autophagy-related protein 2 CAD motif DUF2888 PF11135.8 RUS74059.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) zf-H2C2_2 PF13465.6 RUS74060.1 - 4.9e-50 165.8 165.1 3.8e-07 30.2 1.8 19.0 19 0 0 19 19 19 16 Zinc-finger double domain zf-C2H2 PF00096.26 RUS74060.1 - 1.1e-39 132.7 173.0 0.0013 19.1 0.2 17.2 17 0 0 17 17 17 16 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS74060.1 - 2.8e-37 126.1 160.9 1.1e-06 28.3 3.4 15.6 16 0 0 16 16 16 12 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS74060.1 - 6.4e-28 95.0 158.8 0.0052 17.5 0.2 17.2 17 0 0 17 17 17 14 C2H2-type zinc finger zf-met PF12874.7 RUS74060.1 - 0.00095 19.5 4.8 0.011 16.1 0.3 16.6 17 0 0 17 17 17 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS74060.1 - 0.017 15.4 0.1 0.017 15.4 0.1 16.2 17 0 0 17 17 17 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS74060.1 - 0.021 14.9 0.3 0.021 14.9 0.3 13.6 13 3 0 13 13 13 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS74060.1 - 0.6 9.8 0.1 0.09 12.4 1.2 13.9 8 4 7 15 15 15 0 Zinc-fingers and homeoboxes C2H2 finger domain NucS PF01939.16 RUS74061.1 - 0.063 12.6 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS SNF2_N PF00176.23 RUS74062.1 - 1.1e-49 169.0 0.1 3.2e-49 167.5 0.0 1.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS74062.1 - 1.8e-19 70.1 0.0 2.6e-17 63.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RUS74062.1 - 8.2e-06 25.2 0.0 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 RUS74062.1 - 3.1e-05 24.0 0.1 0.00019 21.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RUS74062.1 - 6.6e-05 22.2 0.0 0.38 9.9 0.0 3.0 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 HHH_3 PF12836.7 RUS74062.1 - 0.041 14.2 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 RUS74062.1 - 0.09 13.4 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 RUS74062.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Syntaxin_2 PF14523.6 RUS74062.1 - 0.25 11.7 1.6 0.56 10.6 0.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein BIR PF00653.21 RUS74063.1 - 3e-23 82.2 0.4 2.4e-14 53.7 0.5 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS74063.1 - 6.7e-07 29.1 10.4 6.7e-07 29.1 10.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Trypsin_2 PF13365.6 RUS74063.1 - 0.00023 22.1 0.1 0.0011 19.9 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain zf-C3HC PF07967.13 RUS74063.1 - 0.011 15.8 0.9 0.3 11.1 0.0 2.9 3 0 0 3 3 3 0 C3HC zinc finger-like HEPN_MAE_28990 PF18737.1 RUS74063.1 - 0.018 14.9 0.5 0.034 14.1 0.5 1.3 1 0 0 1 1 1 0 MAE_28990/MAE_18760-like HEPN Prok-RING_4 PF14447.6 RUS74063.1 - 0.02 14.8 10.7 0.079 12.8 10.7 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Osmo_CC PF08946.10 RUS74063.1 - 0.4 11.0 0.9 0.86 9.9 0.9 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil HLH PF00010.26 RUS74065.1 - 1.3e-14 53.8 0.4 1.6e-14 53.6 0.4 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Branch PF02485.21 RUS74067.1 - 3.2e-36 125.1 0.0 4.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme vATP-synt_E PF01991.18 RUS74068.1 - 1.7e-56 190.8 7.6 1.9e-56 190.6 7.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Cauli_DNA-bind PF03310.13 RUS74068.1 - 0.29 11.2 5.9 2.1 8.5 4.3 2.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Aa_trans PF01490.18 RUS74069.1 - 5.3e-58 196.7 20.3 6.5e-58 196.4 20.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 RUS74070.1 - 5.2e-41 140.7 18.1 6.5e-41 140.4 18.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Alk_phosphatase PF00245.20 RUS74071.1 - 1.3e-64 218.7 1.8 1.4e-40 139.6 0.0 2.0 2 0 0 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 RUS74071.1 - 0.0025 17.2 0.1 0.0036 16.7 0.1 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 RUS74072.1 - 3.9e-18 65.6 0.1 4.7e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase TGase_elicitor PF16683.5 RUS74072.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor BING4CT PF08149.11 RUS74073.1 - 0.094 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 BING4CT (NUC141) domain Macoilin PF09726.9 RUS74073.1 - 5.9 5.3 8.1 11 4.4 8.1 1.5 1 0 0 1 1 1 0 Macoilin family DUF4994 PF16385.5 RUS74074.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Zn_Tnp_IS91 PF14319.6 RUS74074.1 - 1.8 8.7 8.0 0.99 9.5 4.7 2.3 2 1 0 2 2 2 0 Transposase zinc-binding domain Ion_trans PF00520.31 RUS74075.1 - 1.5e-18 67.0 11.1 1.5e-18 67.0 11.1 1.9 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 RUS74075.1 - 1.2e-06 27.5 5.8 2.1e-06 26.7 5.8 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank_3 PF13606.6 RUS74075.1 - 8.4e-06 25.8 0.2 0.52 11.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RUS74075.1 - 1.7e-05 25.3 0.3 0.0013 19.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74075.1 - 0.00012 22.6 0.5 0.06 13.9 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS74075.1 - 0.0022 18.4 0.3 0.46 11.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ion_trans PF00520.31 RUS74076.1 - 2.8e-26 92.2 22.8 4.2e-26 91.7 22.7 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS74076.1 - 3.2e-15 55.9 4.4 3.2e-15 55.9 4.4 2.2 2 1 0 2 2 2 1 Ion channel BTB_2 PF02214.22 RUS74076.1 - 6.5e-10 39.2 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Lig_chan PF00060.26 RUS74076.1 - 0.39 10.6 3.0 2.2 8.1 3.0 2.2 1 1 0 1 1 1 0 Ligand-gated ion channel Fer4_17 PF13534.6 RUS74077.1 - 9.1e-11 42.2 6.4 1.2e-10 41.8 6.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RUS74077.1 - 1.2e-09 38.5 5.1 2e-09 37.7 5.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RUS74077.1 - 2.7e-08 33.8 4.0 3.9e-08 33.3 4.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 RUS74077.1 - 0.00086 19.4 7.6 0.0016 18.5 7.6 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 RUS74077.1 - 0.0012 19.3 8.3 0.0028 18.2 8.3 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 RUS74077.1 - 0.27 11.8 7.6 1 10.0 2.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 RUS74077.1 - 3.4 8.8 15.8 9.5 7.4 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 RUS74077.1 - 6.1 6.8 12.9 12 5.9 6.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Sema PF01403.19 RUS74078.1 - 2.1e-116 389.2 0.3 3.3e-116 388.6 0.0 1.4 2 0 0 2 2 2 1 Sema domain PSI PF01437.25 RUS74078.1 - 1e-07 32.4 5.9 3.2e-07 30.8 5.9 1.9 1 0 0 1 1 1 1 Plexin repeat DHHC PF01529.20 RUS74078.1 - 0.052 13.7 0.1 0.89 9.7 0.2 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase PSI_integrin PF17205.3 RUS74078.1 - 0.17 11.7 4.4 0.45 10.3 4.4 1.7 1 0 0 1 1 1 0 Integrin plexin domain Nha1_C PF08619.10 RUS74079.1 - 0.015 14.5 33.1 0.018 14.3 33.1 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Cwf_Cwc_15 PF04889.12 RUS74079.1 - 0.021 14.6 27.9 0.024 14.4 27.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RUS74079.1 - 0.027 12.7 50.9 0.03 12.6 50.9 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS74079.1 - 0.053 12.3 15.5 0.051 12.3 15.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 RUS74079.1 - 0.19 11.5 36.0 0.23 11.2 36.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 RUS74079.1 - 0.24 11.1 13.1 0.29 10.9 13.1 1.1 1 0 0 1 1 1 0 AAA domain Drc1-Sld2 PF11719.8 RUS74079.1 - 0.79 9.2 30.0 0.91 9.0 30.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 RUS74079.1 - 0.9 8.9 55.3 1.1 8.6 55.3 1.1 1 0 0 1 1 1 0 SDA1 DUF4045 PF13254.6 RUS74079.1 - 1.3 8.6 21.7 1.5 8.4 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BUD22 PF09073.10 RUS74079.1 - 2.8 7.2 44.5 3.1 7.0 44.5 1.1 1 0 0 1 1 1 0 BUD22 SID-1_RNA_chan PF13965.6 RUS74079.1 - 2.9 6.2 6.2 2.9 6.2 6.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 RUS74079.1 - 3.9 7.4 13.2 4.7 7.2 13.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 RUS74079.1 - 5.1 5.1 18.7 5.3 5.0 18.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_polI_A34 PF08208.11 RUS74079.1 - 6.7 6.7 47.8 8.3 6.4 47.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CCSAP PF15748.5 RUS74079.1 - 7.4 6.7 28.7 9.4 6.3 28.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 RUS74079.1 - 9.9 6.1 8.8 11 6.0 8.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region COMM_domain PF07258.14 RUS74080.1 - 1e-21 76.8 1.0 1e-21 76.8 1.0 2.5 3 0 0 3 3 3 1 COMM domain DUF1798 PF08807.10 RUS74080.1 - 0.0011 19.1 1.4 0.0033 17.5 1.4 1.8 1 1 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) SKA2 PF16740.5 RUS74080.1 - 0.0014 18.4 6.7 0.0036 17.1 3.2 3.0 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 SF3a60_bindingd PF12108.8 RUS74080.1 - 0.14 12.0 0.2 0.41 10.6 0.2 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF5053 PF16476.5 RUS74080.1 - 0.32 10.7 1.7 24 4.7 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) IZUMO PF15005.6 RUS74080.1 - 6.7 7.2 6.8 1.8 9.1 2.7 2.0 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated TSP_1 PF00090.19 RUS74081.1 - 8e-28 96.4 134.9 1.1e-06 28.8 7.5 13.4 11 1 2 13 13 13 8 Thrombospondin type 1 domain I-set PF07679.16 RUS74081.1 - 3.4e-10 39.9 0.0 8.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74081.1 - 9.2e-09 35.8 0.0 3.2e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain PLAC PF08686.11 RUS74081.1 - 6.6e-08 33.2 12.1 5.6e-07 30.2 12.1 2.9 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Ig_2 PF13895.6 RUS74081.1 - 1.1e-06 28.8 1.3 7.8e-06 26.1 0.0 3.1 4 0 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 RUS74081.1 - 9.8e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 RUS74081.1 - 0.00046 20.5 0.0 0.0021 18.4 0.0 2.1 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V4R PF02830.18 RUS74081.1 - 0.21 11.6 3.5 0.22 11.6 0.8 2.5 2 0 0 2 2 2 0 V4R domain DUF2793 PF10983.8 RUS74082.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) Lectin_C PF00059.21 RUS74083.1 - 6.4e-06 26.9 0.1 8.6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain AgrD PF05931.11 RUS74083.1 - 0.23 11.5 0.5 0.43 10.7 0.2 1.6 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF4808 PF16066.5 RUS74084.1 - 0.0012 19.4 0.3 0.0024 18.4 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4808) OATP PF03137.20 RUS74084.1 - 0.0083 14.5 0.2 0.01 14.1 0.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.16 RUS74084.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CD34_antigen PF06365.12 RUS74084.1 - 0.01 15.4 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 RUS74084.1 - 0.026 14.4 0.1 0.076 12.9 0.0 1.7 1 1 1 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 RUS74084.1 - 0.027 15.4 1.2 0.076 13.9 1.2 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 RUS74084.1 - 0.039 12.8 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless PRIMA1 PF16101.5 RUS74084.1 - 0.054 13.5 1.0 9.4 6.3 2.9 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Conotoxin PF02950.17 RUS74084.1 - 0.065 14.3 0.1 0.15 13.1 0.1 1.6 1 0 0 1 1 1 0 Conotoxin Miga PF10265.9 RUS74084.1 - 0.1 11.5 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Mitoguardin DUF2615 PF11027.8 RUS74084.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4834 PF16118.5 RUS74084.1 - 0.58 11.2 1.4 1.3 10.0 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_A22B PF04258.13 RUS74086.1 - 8.4e-69 232.2 13.0 1.4e-68 231.5 13.0 1.3 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 RUS74086.1 - 0.0021 18.1 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 PA domain VIT1 PF01988.19 RUS74086.1 - 1.4 8.8 4.5 2.3 8.1 0.6 2.3 2 0 0 2 2 2 0 VIT family PP1 PF07430.11 RUS74087.1 - 1.5e-05 24.9 3.2 0.89 9.6 0.3 4.0 1 1 3 4 4 4 4 Phloem filament protein PP1 cystatin-like domain DUF4476 PF14771.6 RUS74087.1 - 1.8 8.9 8.4 30 5.0 0.1 3.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4476) Acetyltransf_9 PF13527.7 RUS74088.1 - 0.0063 16.6 0.7 10 6.2 0.0 3.6 1 1 2 3 3 3 2 Acetyltransferase (GNAT) domain CysA_C_terminal PF17850.1 RUS74088.1 - 0.22 12.1 24.0 14 6.3 0.3 8.5 2 2 6 8 8 8 0 CysA C-terminal regulatory domain FeS_assembly_P PF01883.19 RUS74088.1 - 4.6 7.5 12.3 20 5.4 0.7 3.7 1 1 2 4 4 4 0 Iron-sulfur cluster assembly protein ZirS_C PF16583.5 RUS74088.1 - 9.8 5.7 7.3 17 5.0 1.6 2.5 1 1 1 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Pkinase PF00069.25 RUS74089.1 - 2.3e-66 223.9 0.0 3.2e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74089.1 - 3.1e-37 128.3 0.0 5.1e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 RUS74089.1 - 2.1e-26 92.2 0.0 3.5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 RUS74089.1 - 2.3e-16 59.4 4.2 4.3e-16 58.5 4.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 RUS74089.1 - 2.5e-05 24.9 0.1 5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RUS74089.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 RUS74089.1 - 0.029 14.0 0.1 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 RUS74089.1 - 0.049 14.0 6.5 0.11 12.8 6.5 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 RUS74089.1 - 0.052 13.1 0.6 0.052 13.1 0.6 1.8 2 0 0 2 2 2 0 PHD-finger WW_like PF17890.1 RUS74089.1 - 0.058 13.5 0.1 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain APH PF01636.23 RUS74089.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS74089.1 - 0.085 11.8 0.1 0.13 11.2 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 RUS74089.1 - 0.18 11.7 4.1 0.37 10.7 4.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 RUS74089.1 - 0.66 10.3 3.7 1.5 9.2 3.7 1.6 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.16 RUS74091.1 - 1.5e-32 112.9 38.2 1.8e-32 112.6 38.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0444 PF15475.6 RUS74091.1 - 0.96 9.8 6.6 13 6.2 2.6 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 7tm_1 PF00001.21 RUS74093.1 - 1.2e-39 136.2 10.8 2.6e-39 135.1 10.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS74093.1 - 3.6e-05 23.3 11.0 3.6e-05 23.3 11.0 2.2 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS74093.1 - 0.00021 21.0 22.8 0.00092 18.9 17.8 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS74093.1 - 0.00035 20.0 11.4 0.0051 16.2 4.7 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv IBD PF10416.9 RUS74093.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD 7tm_1 PF00001.21 RUS74095.1 - 1.9e-29 102.8 1.5 4.7e-28 98.3 1.5 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS74095.1 - 7.6e-05 22.5 1.2 7.6e-05 22.5 1.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS74095.1 - 0.00027 20.4 0.8 0.00027 20.4 0.8 2.4 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS74095.1 - 0.0044 16.8 2.5 0.0059 16.4 0.4 2.1 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 RUS74095.1 - 0.0068 16.0 2.0 0.0068 16.0 2.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF2534 PF10749.9 RUS74096.1 - 0.00099 19.2 11.3 1.5 9.0 1.2 3.9 1 1 3 4 4 4 3 Protein of unknown function (DUF2534) NtCtMGAM_N PF16863.5 RUS74096.1 - 0.035 14.3 0.2 7.3 6.8 0.1 2.2 1 1 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase NHL PF01436.21 RUS74096.1 - 0.084 12.9 5.8 82 3.5 0.1 5.5 6 0 0 6 6 6 0 NHL repeat PPV_E2_C PF00511.17 RUS74096.1 - 1.3 9.3 4.7 29 4.9 0.1 3.1 2 1 1 3 3 3 0 E2 (early) protein, C terminal Erv26 PF04148.13 RUS74096.1 - 1.3 8.8 12.0 0.71 9.7 5.0 2.1 1 1 1 2 2 2 0 Transmembrane adaptor Erv26 7tm_1 PF00001.21 RUS74097.1 - 2e-38 132.3 14.5 2.3e-38 132.0 14.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS74097.1 - 3.4e-07 29.9 13.7 4.5e-07 29.5 13.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS74097.1 - 0.00067 19.0 11.3 0.0038 16.6 11.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw RVT_1 PF00078.27 RUS74098.1 - 0.0083 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 RUS74098.1 - 0.033 13.5 27.7 0.046 13.0 27.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RUS74098.1 - 0.042 13.0 31.3 0.061 12.5 31.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS74098.1 - 0.14 10.2 28.7 0.19 9.8 28.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 RUS74098.1 - 0.25 11.1 8.2 0.27 11.0 6.8 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 RUS74098.1 - 0.38 9.0 14.9 0.53 8.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS74098.1 - 1.6 7.1 12.8 2.1 6.7 12.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS74098.1 - 2.4 6.2 20.3 3.3 5.8 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family PALP PF00291.25 RUS74099.1 - 4.3e-68 229.9 0.0 4.8e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KH_1 PF00013.29 RUS74100.1 - 2.3e-30 104.2 1.1 5.9e-15 54.9 0.6 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 RUS74100.1 - 0.0032 17.3 0.2 0.73 9.7 0.1 2.5 2 0 0 2 2 2 2 KH domain Pyr_redox_3 PF13738.6 RUS74100.1 - 0.05 12.8 0.2 0.077 12.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MOEP19 PF16005.5 RUS74100.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 KH-like RNA-binding domain efThoc1 PF11957.8 RUS74101.1 - 4.1e-46 157.7 3.7 5.5e-46 157.3 3.7 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF3727 PF12527.8 RUS74101.1 - 0.058 13.6 0.1 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3727) UAA PF08449.11 RUS74102.1 - 8.9e-83 278.0 25.6 1.1e-82 277.7 25.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RUS74102.1 - 5.6e-05 23.3 31.1 0.00095 19.4 13.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_M4_C PF02868.15 RUS74103.1 - 1.3e-25 90.2 0.4 3e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 RUS74103.1 - 1.1e-23 84.3 1.5 1.2e-23 84.3 0.2 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 RUS74103.1 - 7e-05 22.6 0.1 7e-05 22.6 0.1 3.2 4 0 0 4 4 4 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 RUS74103.1 - 0.0048 17.4 0.1 0.014 16.0 0.1 1.8 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Glyco_hydro2_C5 PF18565.1 RUS74103.1 - 0.44 10.4 3.6 0.23 11.3 1.1 1.8 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Peptidase_M4_C PF02868.15 RUS74104.1 - 6.1e-26 91.3 0.1 1.3e-25 90.2 0.0 1.6 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 RUS74104.1 - 1.5e-25 90.4 0.1 2.9e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M36 PF02128.15 RUS74104.1 - 3.6e-05 23.1 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Glyco_hydro2_C5 PF18565.1 RUS74104.1 - 0.024 14.5 0.8 0.055 13.3 0.8 1.6 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Ig_3 PF13927.6 RUS74106.1 - 0.00029 21.4 0.4 0.0064 17.1 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 RUS74106.1 - 0.15 12.4 0.4 2.4 8.5 0.1 2.9 3 1 0 3 3 3 0 Immunoglobulin domain LRR_8 PF13855.6 RUS74107.1 - 1.1e-35 121.1 30.2 4.7e-07 29.5 0.9 7.0 2 1 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RUS74107.1 - 1.6e-35 120.5 34.6 1.7e-06 28.2 1.3 9.1 4 2 7 11 11 11 10 Leucine Rich repeats (2 copies) PDZ PF00595.24 RUS74107.1 - 6e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS74107.1 - 4.5e-07 29.6 0.0 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain LRR_5 PF13306.6 RUS74107.1 - 0.0003 20.7 0.0 0.75 9.8 0.0 3.2 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) PDZ_2 PF13180.6 RUS74107.1 - 0.00053 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LRR_1 PF00560.33 RUS74107.1 - 1.5 9.7 30.2 33 5.6 0.1 11.8 12 1 0 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 RUS74107.1 - 4.5 7.6 19.6 20 5.6 0.0 7.8 8 0 0 8 8 8 0 Leucine Rich repeat Helicase_C PF00271.31 RUS74108.1 - 8.1e-09 35.8 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 7tm_1 PF00001.21 RUS74109.1 - 1.9e-16 60.2 7.4 2.2e-11 43.6 7.3 3.1 3 0 0 3 3 3 3 7 transmembrane receptor (rhodopsin family) DNA_pol_A_exo1 PF01612.20 RUS74110.1 - 0.0017 18.1 0.8 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease Mut7-C PF01927.16 RUS74111.1 - 5.4e-19 68.7 2.5 5.2e-11 42.8 0.1 2.3 2 0 0 2 2 2 2 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 RUS74111.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease TruB_N PF01509.18 RUS74112.1 - 1.1e-12 48.5 0.0 1.9e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 RUS74112.1 - 0.008 16.3 0.8 0.034 14.3 0.2 2.2 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 RUS74112.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 RNA pseudouridylate synthase TraB PF01963.17 RUS74113.1 - 0.0059 16.5 1.4 0.01 15.8 1.4 1.3 1 0 0 1 1 1 1 TraB family MIS13 PF08202.11 RUS74113.1 - 0.96 8.7 13.6 0.03 13.6 5.9 2.0 1 1 0 2 2 2 0 Mis12-Mtw1 protein family FlaG PF03646.15 RUS74113.1 - 1.3 9.2 6.1 0.55 10.4 0.5 2.5 2 0 0 2 2 2 0 FlaG protein T3SS_basalb_I PF17001.5 RUS74113.1 - 2.9 8.5 6.3 9.4 6.9 0.2 2.6 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Tubulin PF00091.25 RUS74114.1 - 2.3e-24 86.7 0.0 2.5e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF883 PF05957.13 RUS74115.1 - 1.6 9.4 0.0 1.6 9.4 0.0 3.8 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF883) ANAPC1 PF12859.7 RUS74116.1 - 0.083 13.4 0.1 0.083 13.4 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 CAP_N PF01213.19 RUS74116.1 - 2.3 7.6 6.5 4.4 6.7 6.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UPF0524 PF15823.5 RUS74118.1 - 7.6 5.9 9.6 26 4.1 9.6 2.0 1 0 0 1 1 1 0 UPF0524 of C3orf70 LRAT PF04970.13 RUS74120.1 - 1.7e-30 106.0 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 RUS74120.1 - 0.00076 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C97 PF05903.14 RUS74120.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Histone PF00125.24 RUS74121.1 - 1.9e-38 131.8 0.5 3.5e-38 130.9 0.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS74121.1 - 0.00012 22.3 0.3 0.00024 21.3 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 RUS74121.1 - 0.0071 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RUS74121.1 - 0.025 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 RUS74121.1 - 0.05 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated PIP5K PF01504.18 RUS74122.1 - 9.9e-58 195.5 0.0 2.2e-57 194.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase_Tyr PF07714.17 RUS74123.1 - 8.8e-08 31.7 0.0 9.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS74123.1 - 1.1e-07 31.5 0.1 1.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain GDP_Man_Dehyd PF16363.5 RUS74124.1 - 1.9e-60 205.0 0.0 2.2e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS74124.1 - 1.7e-51 175.0 0.1 2.1e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS74124.1 - 5.6e-18 64.9 0.6 3e-17 62.5 0.5 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RUS74124.1 - 1.9e-14 53.5 0.6 1.9e-13 50.2 0.6 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RUS74124.1 - 3.1e-12 46.2 0.1 4.9e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RUS74124.1 - 2.5e-09 36.7 0.1 8e-07 28.5 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 RUS74124.1 - 1.2e-07 31.4 0.1 3e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 RUS74124.1 - 1.5e-07 31.5 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RUS74124.1 - 7.2e-07 29.3 0.4 1.9e-06 27.9 0.4 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RUS74124.1 - 1.8e-05 24.4 0.8 0.0063 16.1 0.4 2.3 2 0 0 2 2 2 2 NmrA-like family adh_short_C2 PF13561.6 RUS74124.1 - 0.0095 15.5 0.0 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 RUS74124.1 - 0.026 14.4 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RUS74124.1 - 0.12 12.8 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding MMACHC PF16690.5 RUS74126.1 - 4.8e-87 291.2 0.0 5.5e-87 291.0 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family RINGv PF12906.7 RUS74127.1 - 4.9e-13 49.0 1.7 4.9e-13 49.0 1.7 2.8 2 1 0 2 2 2 1 RING-variant domain PAPA-1 PF04795.12 RUS74127.1 - 0.013 16.2 2.2 0.022 15.5 2.2 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region Radial_spoke PF04712.12 RUS74127.1 - 0.03 13.3 1.5 0.038 12.9 1.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein UPF0114 PF03350.16 RUS74127.1 - 0.093 12.9 1.4 0.16 12.2 1.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 SelK_SelG PF10961.8 RUS74127.1 - 0.46 11.1 0.1 0.46 11.1 0.1 1.9 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Rgp1 PF08737.10 RUS74127.1 - 1 8.5 4.2 1.4 8.0 4.2 1.2 1 0 0 1 1 1 0 Rgp1 Peptidase_M14 PF00246.24 RUS74128.1 - 9.6e-12 45.3 0.0 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RUS74128.1 - 8.9e-08 32.5 0.0 2.2e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain WRW PF10206.9 RUS74130.1 - 7.4e-36 122.6 1.1 8.4e-36 122.4 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f SNF2_N PF00176.23 RUS74131.1 - 9e-70 235.1 1.9 2e-69 234.0 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS74131.1 - 3e-19 69.4 0.0 2e-17 63.6 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS74131.1 - 2.1e-05 24.6 0.0 2.1e-05 24.6 0.0 4.4 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Lactamase_B_2 PF12706.7 RUS74132.1 - 3.2e-06 26.8 0.1 6.5e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.14 RUS74132.1 - 0.00015 21.9 0.0 0.027 14.7 0.1 2.4 1 1 1 2 2 2 2 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 RUS74132.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4880 PF16220.5 RUS74132.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) DTHCT PF08070.11 RUS74134.1 - 2 9.2 9.0 4.5 8.0 9.0 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region Phi_1 PF04674.12 RUS74135.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region HPIP_like PF18524.1 RUS74135.1 - 0.41 10.5 4.1 1.7 8.5 0.4 2.4 2 0 0 2 2 2 0 High potential iron-sulfur protein like OrfB_Zn_ribbon PF07282.11 RUS74135.1 - 0.43 10.5 4.1 10 6.1 0.4 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Herpes_UL17 PF04559.12 RUS74136.1 - 0.29 9.9 3.4 0.32 9.7 3.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein TIMELESS PF04821.14 RUS74136.1 - 1.3 8.3 7.4 0.12 11.6 0.4 2.0 2 0 0 2 2 2 0 Timeless protein PRC2_HTH_1 PF18118.1 RUS74136.1 - 7 7.5 13.7 1.7 9.5 2.1 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DivIC PF04977.15 RUS74137.1 - 0.0002 21.0 15.0 0.00099 18.8 2.7 2.5 2 1 0 2 2 2 1 Septum formation initiator DUF2353 PF09789.9 RUS74137.1 - 0.0015 18.0 13.1 0.0019 17.6 13.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) MscS_porin PF12795.7 RUS74137.1 - 0.0049 16.4 10.9 0.017 14.7 10.9 1.7 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain Strep_SA_rep PF06696.11 RUS74137.1 - 0.005 16.8 3.3 0.014 15.3 3.3 1.7 1 0 0 1 1 1 1 Streptococcal surface antigen repeat TolA_bind_tri PF16331.5 RUS74137.1 - 0.0063 16.6 10.3 0.031 14.3 4.8 2.7 1 1 0 2 2 2 1 TolA binding protein trimerisation Mto2_bdg PF12808.7 RUS74137.1 - 0.015 15.5 3.6 0.076 13.3 0.5 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Snapin_Pallidin PF14712.6 RUS74137.1 - 0.016 15.6 13.9 0.045 14.2 2.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin TMF_DNA_bd PF12329.8 RUS74137.1 - 0.017 15.1 19.5 0.054 13.5 7.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SOAR PF16533.5 RUS74137.1 - 0.022 14.7 0.5 0.022 14.7 0.5 2.1 2 0 0 2 2 2 0 STIM1 Orai1-activating region TPR_MLP1_2 PF07926.12 RUS74137.1 - 0.024 14.7 17.7 0.029 14.4 5.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 RUS74137.1 - 0.025 15.5 15.0 0.53 11.2 15.0 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CortBP2 PF09727.9 RUS74137.1 - 0.027 14.4 16.4 0.038 13.9 16.4 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Filament PF00038.21 RUS74137.1 - 0.03 13.9 15.8 0.097 12.2 15.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein DASH_Dad4 PF08650.10 RUS74137.1 - 0.031 14.2 3.1 2.6 8.1 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 YabA PF06156.13 RUS74137.1 - 0.035 14.7 14.2 0.41 11.3 3.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 RUS74137.1 - 0.037 14.1 13.6 0.26 11.4 4.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor HMMR_C PF15908.5 RUS74137.1 - 0.042 14.1 13.2 0.22 11.8 6.2 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 RUS74137.1 - 0.051 14.0 9.2 1.2 9.5 0.7 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 RUS74137.1 - 0.077 13.1 20.3 0.76 9.9 8.6 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Bap31_Bap29_C PF18035.1 RUS74137.1 - 0.11 12.6 17.6 0.1 12.6 2.8 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 RUS74137.1 - 0.12 11.2 18.1 0.16 10.8 6.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 RUS74137.1 - 0.13 12.7 12.9 0.2 12.1 12.9 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 RUS74137.1 - 0.14 12.9 9.9 0.078 13.7 4.4 2.1 1 1 1 2 2 2 0 Occludin homology domain Mst1_SARAH PF11629.8 RUS74137.1 - 0.15 12.2 5.4 3.2 7.9 0.3 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1664 PF07889.12 RUS74137.1 - 0.16 12.0 11.7 0.75 9.8 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KLRAQ PF10205.9 RUS74137.1 - 0.17 12.1 16.9 1.3 9.3 7.9 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ADIP PF11559.8 RUS74137.1 - 0.17 11.9 16.1 1 9.4 5.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PI_PP_I PF18363.1 RUS74137.1 - 0.18 12.0 5.7 0.51 10.5 1.4 2.1 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain HD_3 PF13023.6 RUS74137.1 - 0.21 11.5 8.4 0.57 10.1 1.6 2.1 1 1 1 2 2 2 0 HD domain Rootletin PF15035.6 RUS74137.1 - 0.22 11.5 15.6 0.54 10.3 15.6 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Dzip-like_N PF13815.6 RUS74137.1 - 0.24 11.4 11.3 0.92 9.5 1.6 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF5621 PF18532.1 RUS74137.1 - 0.28 11.1 5.6 0.1 12.5 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5621) JIP_LZII PF16471.5 RUS74137.1 - 0.32 11.2 13.1 0.33 11.2 4.4 2.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4763 PF15960.5 RUS74137.1 - 0.35 10.1 13.8 0.54 9.5 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Csm1_N PF18504.1 RUS74137.1 - 0.38 11.1 15.2 0.5 10.7 4.4 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Tli4_N PF18443.1 RUS74137.1 - 0.42 11.0 4.3 1.7 9.0 4.4 1.9 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Rho_Binding PF08912.11 RUS74137.1 - 0.47 11.3 18.7 0.7 10.7 4.0 2.4 1 1 1 2 2 2 0 Rho Binding PspA_IM30 PF04012.12 RUS74137.1 - 0.66 9.5 18.5 0.51 9.9 7.8 2.0 1 1 1 2 2 2 0 PspA/IM30 family CC2-LZ PF16516.5 RUS74137.1 - 0.78 10.1 17.3 0.43 11.0 6.5 2.1 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GrpE PF01025.19 RUS74137.1 - 0.84 9.3 16.4 0.3 10.7 6.2 2.0 1 1 1 2 2 2 0 GrpE BST2 PF16716.5 RUS74137.1 - 0.85 10.2 16.1 1.5 9.4 3.7 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CREPT PF16566.5 RUS74137.1 - 0.92 9.7 15.1 0.45 10.7 3.7 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour LPP PF04728.13 RUS74137.1 - 1.2 9.5 8.8 1.8 9.0 0.5 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4200 PF13863.6 RUS74137.1 - 1.5 9.2 19.2 14 6.1 19.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.12 RUS74137.1 - 1.6 9.2 18.1 0.71 10.4 4.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF4878 PF12870.7 RUS74137.1 - 1.8 8.9 10.4 0.35 11.2 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4878) UPF0242 PF06785.11 RUS74137.1 - 1.8 8.6 16.8 9 6.3 16.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-Q PF13094.6 RUS74137.1 - 2.3 8.4 14.5 5.6 7.1 3.1 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 RUS74137.1 - 2.4 7.4 8.8 3.5 6.9 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 RUS74137.1 - 2.6 7.3 16.0 1.4 8.2 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF641 PF04859.12 RUS74137.1 - 3 8.2 15.0 0.69 10.2 3.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Swi5 PF07061.11 RUS74137.1 - 3.3 7.8 15.6 4.6 7.4 4.6 2.6 1 1 1 2 2 2 0 Swi5 V_ATPase_I PF01496.19 RUS74137.1 - 3.6 5.4 10.4 4 5.2 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 RUS74137.1 - 4.3 7.8 9.8 9.9 6.7 2.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 RUS74137.1 - 4.8 6.7 13.6 3.8 7.1 2.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region SlyX PF04102.12 RUS74137.1 - 6.3 7.5 11.3 13 6.5 4.3 2.3 1 1 1 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 RUS74137.1 - 6.6 6.2 10.5 7.6 6.0 10.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 RUS74137.1 - 7.3 7.1 10.3 4 8.0 1.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 RUS74137.1 - 7.5 6.3 9.6 1.4 8.7 3.7 1.9 1 1 1 2 2 2 0 USP8 interacting Exo_endo_phos PF03372.23 RUS74138.1 - 6.1e-10 39.0 0.0 2.8e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS74138.1 - 0.01 15.7 0.1 0.19 11.6 0.0 2.8 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase UPF0181 PF03701.14 RUS74138.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) DUF3615 PF12274.8 RUS74139.1 - 0.0057 17.1 0.7 0.02 15.4 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3615) DUF2201_N PF13203.6 RUS74139.1 - 0.11 12.1 5.0 0.17 11.5 5.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Methyltransf_31 PF13847.6 RUS74140.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain LpoB PF13036.6 RUS74140.1 - 0.12 12.3 1.0 0.87 9.5 0.1 2.3 2 0 0 2 2 2 0 Peptidoglycan-synthase activator LpoB RVT_1 PF00078.27 RUS74141.1 - 0.0033 17.0 0.1 0.0054 16.3 0.1 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MADF_DNA_bdg PF10545.9 RUS74141.1 - 0.16 12.3 2.7 0.43 10.9 2.7 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_hydro_31 PF01055.26 RUS74142.1 - 2.6e-65 221.4 0.5 7e-33 114.5 0.0 3.1 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 PRP8_domainIV PF12134.8 RUS74142.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 PRP8 domain IV core Ank_2 PF12796.7 RUS74143.1 - 4.9e-54 180.9 9.0 4.8e-15 55.9 0.6 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74143.1 - 2.2e-39 133.4 9.8 4.9e-09 36.5 0.1 7.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS74143.1 - 8.9e-38 127.1 6.5 0.001 19.4 0.2 9.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 RUS74143.1 - 4e-33 109.7 16.5 0.00095 19.5 0.0 10.3 10 1 0 10 10 9 8 Ankyrin repeat Ank_5 PF13857.6 RUS74143.1 - 3.7e-30 103.6 5.6 1.1e-06 28.7 0.1 7.5 4 1 4 8 8 8 7 Ankyrin repeats (many copies) TPR_12 PF13424.6 RUS74143.1 - 9.3e-05 22.6 0.6 0.21 11.9 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RUS74143.1 - 0.00051 19.8 0.4 0.75 9.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TRAF_BIRC3_bd PF16673.5 RUS74143.1 - 0.011 15.5 0.1 0.032 14.0 0.1 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DUF3384 PF11864.8 RUS74143.1 - 0.017 14.0 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) TPR_1 PF00515.28 RUS74143.1 - 0.15 11.9 0.4 1.4 8.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74143.1 - 0.2 11.8 5.4 1 9.6 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RQC PF09382.10 RUS74144.1 - 1.7e-19 69.7 0.0 4.8e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 RUS74144.1 - 5.7e-18 65.3 0.0 7.4e-17 61.7 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HTH_40 PF14493.6 RUS74144.1 - 6.6e-17 61.8 0.0 2.5e-16 59.9 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain DEAD PF00270.29 RUS74144.1 - 3.9e-16 59.3 0.0 2.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.23 RUS74144.1 - 2.1e-14 53.2 0.0 5.8e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 HRDC domain RecQ_Zn_bind PF16124.5 RUS74144.1 - 1.2e-10 42.0 2.3 3.3e-10 40.5 2.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Sigma70_r4_2 PF08281.12 RUS74144.1 - 2.1e-07 30.5 0.1 6.3e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 ResIII PF04851.15 RUS74144.1 - 2.8e-07 30.7 0.0 5.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GerE PF00196.19 RUS74144.1 - 0.0074 15.8 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF1804 PF08822.11 RUS74144.1 - 0.12 12.3 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Sigma70_r4 PF04545.16 RUS74144.1 - 0.19 11.3 1.1 2.5 7.7 0.1 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 An_peroxidase PF03098.15 RUS74145.1 - 4.6e-135 451.2 0.0 5.6e-135 450.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Deltaretro_Tax PF05599.11 RUS74145.1 - 0.22 12.1 0.1 0.45 11.1 0.1 1.4 1 0 0 1 1 1 0 Deltaretrovirus Tax protein An_peroxidase PF03098.15 RUS74146.1 - 3e-161 537.6 0.0 3.5e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase CDV3 PF15359.6 RUS74146.1 - 0.11 12.9 4.0 0.23 11.9 4.0 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 PRR18 PF15671.5 RUS74146.1 - 0.15 12.0 7.9 0.29 11.0 7.9 1.4 1 0 0 1 1 1 0 Proline-rich protein family 18 Pkinase PF00069.25 RUS74147.1 - 1.8e-60 204.5 0.0 2.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74147.1 - 1.7e-44 152.0 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 RUS74147.1 - 3.1e-19 68.9 0.5 6.3e-19 68.0 0.5 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 RUS74147.1 - 2.6e-05 23.2 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS74147.1 - 0.00078 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS74147.1 - 0.011 15.6 0.1 0.065 13.1 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family PDZ PF00595.24 RUS74148.1 - 5.6e-55 183.6 0.4 2.5e-16 59.8 0.0 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 RUS74148.1 - 1.7e-24 85.4 4.8 3.3e-06 26.9 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 RUS74148.1 - 1.3e-16 60.7 0.4 0.002 18.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 RUS74148.1 - 2.3e-08 33.7 6.0 2.3e-08 33.7 6.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS74148.1 - 3.9e-07 30.3 4.4 3.9e-07 30.3 4.4 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 RUS74148.1 - 9.5e-07 28.7 4.4 9.5e-07 28.7 4.4 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS74148.1 - 4.1e-06 26.7 7.9 1.5e-05 24.9 7.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS74148.1 - 5.3e-06 26.2 4.7 5.3e-06 26.2 4.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS74148.1 - 5.4e-06 26.2 2.8 5.4e-06 26.2 2.8 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 RUS74148.1 - 1.2e-05 25.9 2.1 3e-05 24.6 2.1 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 RUS74148.1 - 0.00014 21.9 5.7 0.00014 21.9 5.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 RUS74148.1 - 0.00032 21.1 4.6 0.00032 21.1 4.6 2.0 1 1 0 1 1 1 1 TRAF-like zinc-finger zf-rbx1 PF12678.7 RUS74148.1 - 0.0024 18.1 7.8 0.0036 17.5 5.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-Nse PF11789.8 RUS74148.1 - 0.0024 17.6 1.3 0.0068 16.2 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 RUS74148.1 - 0.3 11.3 7.9 0.21 11.8 4.8 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Spore_YhaL PF14147.6 RUS74148.1 - 0.56 9.9 0.0 0.56 9.9 0.0 1.8 2 0 0 2 2 1 0 Sporulation protein YhaL Sina PF03145.16 RUS74148.1 - 1.4 8.8 5.7 0.1 12.5 0.8 1.6 2 0 0 2 2 1 0 Seven in absentia protein family Prok-RING_4 PF14447.6 RUS74148.1 - 3 7.8 9.4 0.3 11.0 4.0 2.2 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 LRR_8 PF13855.6 RUS74149.1 - 3.5e-46 154.8 87.3 1.3e-09 37.7 2.3 8.9 3 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 RUS74149.1 - 3.7e-41 138.4 59.2 2.7e-05 24.4 0.3 10.9 8 2 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS74149.1 - 8.7e-12 44.9 29.3 4.6e-06 26.3 5.3 5.7 2 2 5 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 RUS74149.1 - 2e-08 33.6 54.8 0.89 10.4 0.1 15.5 15 2 2 17 17 17 5 Leucine Rich Repeat LRR_6 PF13516.6 RUS74149.1 - 0.01 15.8 60.1 6.6 7.1 0.0 14.2 14 0 0 14 14 14 0 Leucine Rich repeat Trypsin_2 PF13365.6 RUS74152.1 - 5.8e-05 24.0 0.0 0.00072 20.5 0.0 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain Pyrophosphatase PF00719.19 RUS74153.1 - 5.3e-56 188.9 1.4 7.9e-56 188.3 1.4 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase HMG_box PF00505.19 RUS74154.1 - 8.2e-21 74.2 0.3 1.8e-20 73.1 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS74154.1 - 9.5e-08 32.5 0.7 9.5e-08 32.5 0.7 2.0 2 0 0 2 2 2 1 HMG-box domain CTNNB1_binding PF08347.11 RUS74154.1 - 6.3e-06 26.5 14.2 0.0022 18.2 14.2 2.8 1 1 0 1 1 1 1 N-terminal CTNNB1 binding YL1_C PF08265.11 RUS74154.1 - 0.34 10.7 1.3 0.68 9.8 1.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Vmethyltransf_C PF08456.10 RUS74154.1 - 0.54 9.8 2.3 0.42 10.1 0.8 1.5 2 0 0 2 2 2 0 Viral methyltransferase C-terminal DUF4203 PF13886.6 RUS74156.1 - 1.5e-12 47.6 13.4 1.8e-12 47.4 13.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2417 PF10329.9 RUS74156.1 - 0.035 13.5 3.2 0.064 12.7 3.2 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) SIKE PF05769.11 RUS74157.1 - 1e-61 208.0 16.3 1.7e-61 207.3 16.3 1.4 1 0 0 1 1 1 1 SIKE family Mto2_bdg PF12808.7 RUS74157.1 - 0.046 14.0 11.0 1.7 9.0 0.0 4.1 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MCC-bdg_PDZ PF10506.9 RUS74157.1 - 0.057 13.4 8.3 0.98 9.5 1.8 2.8 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TolA_bind_tri PF16331.5 RUS74157.1 - 0.47 10.6 15.3 0.21 11.7 10.9 2.6 2 1 1 3 3 3 0 TolA binding protein trimerisation PTPRCAP PF15713.5 RUS74157.1 - 4.7 7.5 17.6 0.28 11.5 11.6 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NYD-SP28_assoc PF14775.6 RUS74157.1 - 7.6 6.7 8.6 2.8 8.1 1.7 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Epimerase PF01370.21 RUS74158.1 - 3.3e-10 39.8 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS74158.1 - 6e-10 38.6 0.0 1.6e-08 33.9 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 RUS74158.1 - 4.7e-07 29.6 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RUS74158.1 - 5.6e-06 26.4 0.0 1.8e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 RUS74158.1 - 0.00013 21.2 0.0 0.0018 17.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RUS74158.1 - 0.011 15.0 0.8 2.8 7.0 0.3 3.0 2 1 1 3 3 3 0 Male sterility protein GDP_Man_Dehyd PF16363.5 RUS74158.1 - 0.032 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HCV_NS5a PF01506.19 RUS74158.1 - 0.25 11.2 0.5 0.88 9.5 0.1 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Casc1_N PF15927.5 RUS74159.1 - 1.9e-50 171.4 15.6 1.9e-50 171.4 15.6 3.6 4 0 0 4 4 4 1 Cancer susceptibility candidate 1 N-terminus BUD22 PF09073.10 RUS74159.1 - 0.0042 16.5 11.9 0.0042 16.5 11.9 3.0 2 1 0 3 3 3 1 BUD22 Na_trans_assoc PF06512.13 RUS74159.1 - 0.4 10.9 15.2 0.44 10.8 11.7 2.7 2 1 0 2 2 2 0 Sodium ion transport-associated MFS_1 PF07690.16 RUS74160.1 - 2.2e-24 86.0 34.6 2.7e-24 85.8 34.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS74160.1 - 0.15 10.8 18.2 0.024 13.5 9.3 2.4 1 1 1 2 2 2 0 MFS_1 like family IncD PF17628.2 RUS74160.1 - 1.2 8.9 8.1 0.096 12.5 2.8 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D Phage_holin_5_2 PF16079.5 RUS74160.1 - 2.8 8.4 11.0 0.36 11.2 0.5 3.1 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V AtpR PF12966.7 RUS74160.1 - 4.3 7.9 14.9 2.7 8.5 2.5 3.1 2 1 0 2 2 2 0 N-ATPase, AtpR subunit UPF0444 PF15475.6 RUS74161.1 - 1.3e-09 38.2 7.9 2.7e-08 34.0 7.9 2.2 1 1 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 NR_Repeat PF14046.6 RUS74161.1 - 0.18 12.0 0.3 1.3 9.3 0.1 2.0 1 1 1 2 2 2 0 Nuclear receptor repeat RVT_1 PF00078.27 RUS74162.1 - 1.9e-07 30.9 2.5 0.00032 20.3 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Inositol_P PF00459.25 RUS74163.1 - 1.5e-24 87.0 0.3 1.8e-24 86.7 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family 7tm_1 PF00001.21 RUS74164.1 - 4.4e-21 75.4 8.0 4.4e-21 75.4 8.0 2.2 2 1 0 2 2 1 1 7 transmembrane receptor (rhodopsin family) NARP1 PF12569.8 RUS74164.1 - 7.9e-06 25.1 15.0 9.8e-06 24.8 15.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 V_ATPase_I PF01496.19 RUS74164.1 - 4e-05 21.8 3.2 5.4e-05 21.3 3.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF913 PF06025.12 RUS74164.1 - 8.6e-05 21.7 0.8 0.00012 21.2 0.8 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Zip PF02535.22 RUS74164.1 - 0.00018 20.8 0.9 0.00032 20.1 0.9 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter SAPS PF04499.15 RUS74164.1 - 0.00027 19.9 1.4 0.00031 19.7 1.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein TLP-20 PF06088.11 RUS74164.1 - 0.0015 18.5 1.9 0.0024 17.8 1.9 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FYDLN_acid PF09538.10 RUS74164.1 - 0.0067 17.1 20.0 0.011 16.4 20.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) PA26 PF04636.13 RUS74164.1 - 0.011 14.7 1.3 0.014 14.3 1.3 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ASC PF00858.24 RUS74164.1 - 0.012 14.6 1.4 0.015 14.3 0.2 1.7 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel Rtf2 PF04641.12 RUS74164.1 - 0.013 14.9 17.9 0.02 14.3 17.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger AAA_23 PF13476.6 RUS74164.1 - 0.027 15.0 17.2 0.041 14.4 17.2 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 RUS74164.1 - 0.031 14.5 35.2 0.046 14.0 35.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RAB3GAP2_C PF14656.6 RUS74164.1 - 0.069 11.4 4.6 0.1 10.8 4.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus EBV-NA3 PF05009.12 RUS74164.1 - 0.12 11.9 1.4 0.21 11.1 1.4 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Pox_Ag35 PF03286.14 RUS74164.1 - 0.17 11.6 31.6 0.28 11.0 31.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5308 PF17233.2 RUS74164.1 - 0.19 12.0 1.6 0.3 11.3 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Nop14 PF04147.12 RUS74164.1 - 0.19 9.9 31.1 0.25 9.5 31.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS74164.1 - 0.19 11.0 35.5 0.28 10.5 35.5 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 RUS74164.1 - 0.2 11.7 18.7 0.4 10.7 18.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RPN2_C PF18004.1 RUS74164.1 - 0.22 11.4 29.0 0.39 10.6 29.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PIP5K PF01504.18 RUS74164.1 - 0.41 9.8 6.0 0.66 9.1 6.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Vfa1 PF08432.10 RUS74164.1 - 0.42 10.9 27.5 0.75 10.1 27.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 RUS74164.1 - 0.44 9.7 15.6 0.79 8.8 15.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM60A PF15396.6 RUS74164.1 - 0.58 10.1 14.5 1.2 9.1 14.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A BORG_CEP PF14957.6 RUS74164.1 - 0.69 11.1 13.4 1.3 10.2 13.4 1.4 1 0 0 1 1 1 0 Cdc42 effector DDHD PF02862.17 RUS74164.1 - 0.79 9.8 6.7 1.3 9.1 6.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF1754 PF08555.10 RUS74164.1 - 0.8 10.5 38.7 1.4 9.7 38.7 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2052 PF09747.9 RUS74164.1 - 1.1 9.4 28.8 2 8.5 28.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF789 PF05623.12 RUS74164.1 - 1.4 8.6 9.8 6.6 6.3 9.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF789) DUF4820 PF16091.5 RUS74164.1 - 1.4 8.2 17.3 1.4 8.2 15.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Rrn6 PF10214.9 RUS74164.1 - 1.5 7.3 7.8 2 6.8 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SID-1_RNA_chan PF13965.6 RUS74164.1 - 1.7 7.0 13.7 5.7 5.2 13.7 1.8 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Sigma_reg_N PF13800.6 RUS74164.1 - 2.2 8.6 6.0 6 7.2 1.2 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PPP4R2 PF09184.11 RUS74164.1 - 2.5 7.6 35.1 19 4.7 36.3 1.7 2 0 0 2 2 2 0 PPP4R2 SpoIIP PF07454.11 RUS74164.1 - 2.8 7.3 21.0 4 6.8 21.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 RUS74164.1 - 5.7 6.3 7.6 8.7 5.7 7.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin zf-Di19 PF05605.12 RUS74165.1 - 2.7e-05 24.4 8.3 0.022 15.1 0.6 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 RUS74165.1 - 0.0076 16.6 25.1 0.75 10.4 4.8 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type CdiI_N PF18228.1 RUS74165.1 - 0.045 13.6 0.2 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 CdiI N-terminal domain zf-H2C2_2 PF13465.6 RUS74165.1 - 0.052 14.0 10.0 4.5 7.9 1.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS74165.1 - 0.17 12.8 24.4 7.5 7.7 3.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS74165.1 - 0.22 11.2 9.9 1 9.1 1.8 2.7 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain EthD PF07110.11 RUS74165.1 - 0.37 12.0 3.2 1.3 10.2 0.9 2.5 2 1 1 3 3 3 0 EthD domain zf-H2C2_5 PF13909.6 RUS74165.1 - 0.53 10.1 20.0 0.062 13.1 4.3 4.4 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Ribosomal_L37ae PF01780.19 RUS74165.1 - 0.7 10.0 4.9 5.7 7.1 0.3 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family TFIIS_C PF01096.18 RUS74165.1 - 0.83 9.6 4.9 9.6 6.2 0.3 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_5 PF13909.6 RUS74166.1 - 5.6e-06 26.0 29.7 6.5e-05 22.6 2.7 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RUS74166.1 - 0.0019 18.5 39.6 0.014 15.8 0.6 5.3 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 RUS74166.1 - 0.0027 17.3 13.9 0.085 12.5 4.4 3.1 3 0 0 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 RUS74166.1 - 0.0033 17.7 17.3 0.13 12.6 1.9 3.2 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RUS74166.1 - 0.014 16.2 34.4 1.1 10.2 2.5 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger Actin_micro PF17003.5 RUS74166.1 - 0.099 11.8 7.8 1.6 7.8 0.1 2.1 1 1 0 2 2 2 0 Putative actin-like family zf-met PF12874.7 RUS74167.1 - 0.023 15.1 1.4 0.023 15.1 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RUS74167.1 - 0.057 13.9 2.4 0.057 13.9 2.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS74167.1 - 0.19 12.6 13.6 0.17 12.8 2.0 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger ubiquitin PF00240.23 RUS74169.1 - 3.8e-35 119.5 0.3 4.6e-35 119.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS74169.1 - 4.1e-17 61.8 0.4 5e-17 61.5 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.17 RUS74169.1 - 5.4e-09 35.8 0.3 9.6e-09 35.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Ubiquitin_2 PF14560.6 RUS74169.1 - 2.5e-06 27.8 0.1 9.8e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 RUS74169.1 - 0.001 18.9 0.0 0.0026 17.7 0.0 1.8 1 1 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RUS74169.1 - 0.0028 17.7 0.0 0.0069 16.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 RUS74169.1 - 0.0037 17.6 0.1 0.0049 17.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RUS74169.1 - 0.014 15.4 0.7 5.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 RUS74169.1 - 0.056 14.0 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Bud13 PF09736.9 RUS74170.1 - 5.2e-44 150.2 16.4 5.2e-44 150.2 16.4 5.0 3 1 1 5 5 5 1 Pre-mRNA-splicing factor of RES complex sCache_like PF16736.5 RUS74170.1 - 0.086 12.9 0.2 0.086 12.9 0.2 2.8 2 1 0 2 2 2 0 Single Cache-like DHR10 PF18595.1 RUS74170.1 - 2.7 8.1 26.8 1.5 8.9 12.6 2.7 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Fibrinogen_C PF00147.18 RUS74171.1 - 9.5e-50 169.4 3.1 1.3e-49 169.0 3.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain zf-C2H2 PF00096.26 RUS74172.1 - 3e-16 58.9 57.9 0.0011 19.3 3.9 9.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS74172.1 - 1.4e-14 53.7 51.9 3e-06 27.4 1.5 9.2 9 0 0 9 9 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS74172.1 - 1.2e-11 44.4 61.2 0.0009 19.9 2.1 9.8 8 1 0 8 8 8 6 C2H2-type zinc finger BTB PF00651.31 RUS74172.1 - 7.9e-10 38.9 0.0 2.3e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 RUS74172.1 - 0.00082 19.3 32.0 0.2 11.7 0.8 5.9 5 0 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 RUS74172.1 - 0.0041 17.2 18.9 0.85 9.8 1.1 5.0 3 1 1 4 4 4 2 Zinc ribbon domain zf-H2C2_5 PF13909.6 RUS74172.1 - 0.013 15.2 2.7 0.013 15.2 2.7 5.7 6 0 0 6 6 6 0 C2H2-type zinc-finger domain DAP3 PF10236.9 RUS74172.1 - 0.034 13.3 2.3 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 zf-Dof PF02701.15 RUS74172.1 - 0.56 10.4 8.6 0.15 12.2 2.0 3.2 2 1 0 2 2 2 0 Dof domain, zinc finger zf_UBZ PF18439.1 RUS74172.1 - 0.86 9.2 13.3 2.9 7.5 0.1 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 RUS74172.1 - 1 9.0 14.9 0.043 13.4 1.5 4.2 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 RUS74172.1 - 1.4 8.8 14.0 1.1 9.1 0.2 4.0 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 RUS74172.1 - 1.6 8.6 8.9 2.3 8.1 0.5 3.6 2 1 1 3 3 3 0 GAGA factor zf_C2H2_ZHX PF18387.1 RUS74172.1 - 1.9 8.2 26.4 3.4 7.4 3.1 6.2 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_10 PF16588.5 RUS74174.1 - 6.9 6.5 7.6 18 5.1 0.9 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger Claudin_3 PF06653.11 RUS74175.1 - 1.3e-08 35.0 1.1 2.3e-08 34.2 1.1 1.4 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RUS74175.1 - 8.4e-05 22.4 9.8 0.0069 16.2 8.0 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS74175.1 - 0.11 12.4 4.7 0.2 11.5 4.7 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Glyco_tran_10_N PF17039.5 RUS74176.1 - 3.1e-12 46.9 0.1 5e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 RUS74177.1 - 1.2e-48 165.2 0.6 1.3e-48 165.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Pou PF00157.17 RUS74178.1 - 4.4e-36 122.7 0.1 4.4e-36 122.7 0.1 2.3 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RUS74178.1 - 3.2e-16 58.9 0.1 3.2e-16 58.9 0.1 2.5 2 0 0 2 2 2 1 Homeodomain HTH_3 PF01381.22 RUS74178.1 - 0.066 13.3 0.4 5.3 7.2 0.0 3.6 2 1 1 3 3 3 0 Helix-turn-helix Homeobox_KN PF05920.11 RUS74178.1 - 0.09 12.7 0.0 0.09 12.7 0.0 2.4 2 0 0 2 2 2 0 Homeobox KN domain Nas2_N PF18265.1 RUS74179.1 - 1.3e-30 105.1 0.2 1.9e-30 104.6 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RUS74179.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS74179.1 - 2.3e-06 27.8 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS74179.1 - 4e-05 23.9 0.0 8.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 RUS74179.1 - 0.012 16.0 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain AIRC PF00731.20 RUS74179.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AIR carboxylase FlaC_arch PF05377.11 RUS74179.1 - 0.4 11.1 4.0 3.6 8.0 1.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RhoGEF PF00621.20 RUS74181.1 - 2e-15 57.5 0.3 3e-15 56.9 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain PDZ_6 PF17820.1 RUS74181.1 - 1.3e-12 47.3 0.1 3.2e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS74181.1 - 4.3e-07 30.2 0.1 9.5e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS74181.1 - 1.9e-06 28.1 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RUS74181.1 - 0.024 14.6 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain AIG1 PF04548.16 RUS74182.1 - 1e-43 149.1 0.0 1e-43 149.1 0.0 1.9 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS74182.1 - 1.2e-08 35.1 0.0 3.2e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Caldesmon PF02029.15 RUS74182.1 - 0.0008 18.3 29.3 0.00095 18.0 29.3 1.1 1 0 0 1 1 1 1 Caldesmon Septin PF00735.18 RUS74182.1 - 0.0022 17.3 0.0 0.0058 16.0 0.0 1.7 1 0 0 1 1 1 1 Septin Borrelia_P83 PF05262.11 RUS74182.1 - 0.063 11.8 23.7 0.08 11.4 23.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Golgin_A5 PF09787.9 RUS74182.1 - 0.92 8.9 29.7 1.7 8.0 29.7 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4228 PF14009.6 RUS74182.1 - 1.7 9.0 12.8 3.2 8.1 12.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Dynamin_N PF00350.23 RUS74182.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.9 2 2 1 3 3 3 0 Dynamin family RR_TM4-6 PF06459.12 RUS74182.1 - 4.4 7.0 16.1 7.9 6.2 16.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 RUS74182.1 - 6.4 5.5 10.5 9.5 4.9 10.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter I-set PF07679.16 RUS74183.1 - 2e-33 114.3 0.3 1.6e-12 47.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74183.1 - 6.2e-32 110.0 2.0 1.9e-10 41.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS74183.1 - 1.1e-21 77.0 1.6 1.9e-07 31.3 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS74183.1 - 1.5e-19 69.9 0.8 3.1e-05 24.0 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS74183.1 - 3.3e-17 62.6 1.1 2.5e-07 30.8 0.7 4.3 4 0 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS74183.1 - 1.3e-06 27.8 1.0 0.0072 15.9 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin domain C1-set PF07654.15 RUS74183.1 - 0.0023 18.3 1.6 4.7 7.6 1.0 3.5 3 2 0 3 3 3 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 RUS74183.1 - 0.004 17.2 0.9 8.2 6.6 0.3 3.8 3 2 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 RUS74183.1 - 0.012 15.5 1.7 5 7.1 0.1 3.6 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain OMS28_porin PF03532.13 RUS74184.1 - 0.17 11.1 2.5 0.36 10.0 2.5 1.5 1 0 0 1 1 1 0 OMS28 porin PY_rept_46 PF09689.10 RUS74184.1 - 0.28 11.8 3.5 3 8.5 0.3 3.3 3 0 0 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) Calponin PF00402.18 RUS74184.1 - 1.4 8.6 12.9 1.6 8.4 0.9 3.7 3 1 0 3 3 3 0 Calponin family repeat Gal-3-0_sulfotr PF06990.11 RUS74185.1 - 3.4e-50 171.1 1.7 4.3e-50 170.8 1.7 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS74185.1 - 7.3e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family BrnA_antitoxin PF14384.6 RUS74186.1 - 0.094 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Orf78 PF06024.12 RUS74187.1 - 0.047 14.0 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) Alpha_GJ PF03229.13 RUS74187.1 - 0.078 13.5 6.8 0.11 13.1 6.8 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF3972 PF13118.6 RUS74188.1 - 0.011 16.1 6.3 0.015 15.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) YbfN PF13982.6 RUS74188.1 - 0.022 15.0 1.3 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF29 PF01724.16 RUS74188.1 - 0.032 14.5 3.0 0.038 14.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF29 Spc7 PF08317.11 RUS74188.1 - 0.052 12.4 10.1 0.069 12.0 10.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 RUS74188.1 - 0.059 13.5 10.4 0.079 13.0 10.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5043 PF16446.5 RUS74188.1 - 0.074 13.0 0.2 0.085 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) DUF724 PF05266.14 RUS74188.1 - 0.084 12.7 8.1 0.1 12.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CREPT PF16566.5 RUS74188.1 - 0.094 12.9 9.3 0.089 13.0 8.3 1.4 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3450 PF11932.8 RUS74188.1 - 0.13 11.6 8.0 0.15 11.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 RUS74188.1 - 0.13 12.8 11.0 0.09 13.3 8.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 RUS74188.1 - 0.19 11.0 2.4 0.23 10.7 2.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FapA PF03961.13 RUS74188.1 - 0.29 9.7 5.2 0.33 9.5 5.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1216 PF06746.11 RUS74188.1 - 0.31 11.1 6.2 1.1 9.3 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Seryl_tRNA_N PF02403.22 RUS74188.1 - 0.41 10.9 9.4 0.46 10.7 1.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.8 RUS74188.1 - 0.41 10.0 11.3 0.52 9.7 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1043 PF06295.12 RUS74188.1 - 0.52 10.3 6.9 0.83 9.7 2.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 RUS74188.1 - 0.58 10.2 4.4 1.6 8.8 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 RUS74188.1 - 1.9 9.6 4.8 0.65 11.1 1.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) TMPIT PF07851.13 RUS74188.1 - 2.8 7.1 6.8 3.6 6.8 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HA2 PF04408.23 RUS74189.1 - 2.9e-21 75.8 0.0 2.9e-21 75.8 0.0 3.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS74189.1 - 1.1e-19 70.5 0.1 2.7e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS74189.1 - 4.5e-14 52.7 0.1 3.8e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS74189.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 RUS74189.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS74189.1 - 0.00018 21.8 0.0 0.0006 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RUS74189.1 - 0.00036 19.7 0.0 0.00092 18.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 RUS74189.1 - 0.0019 18.5 0.1 0.0094 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 RUS74189.1 - 0.032 14.2 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain PWI PF01480.17 RUS74189.1 - 0.078 13.3 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 PWI domain Sigma54_activ_2 PF14532.6 RUS74189.1 - 0.11 12.6 0.3 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain VWA PF00092.28 RUS74190.1 - 6.6e-21 75.3 0.3 4.2e-14 53.2 0.2 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS74190.1 - 4.3e-14 53.0 1.1 2e-09 38.1 0.4 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 RUS74190.1 - 0.00012 22.1 0.9 0.0058 16.6 0.2 3.2 2 1 1 3 3 3 1 von Willebrand factor type A domain Usp PF00582.26 RUS74190.1 - 0.035 14.6 0.1 0.092 13.2 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein family Metallophos PF00149.28 RUS74191.1 - 6e-41 141.2 0.1 7.8e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS74191.1 - 1.7e-17 63.5 0.5 4.7e-17 62.2 0.3 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain FAR1 PF03101.15 RUS74192.1 - 0.00067 20.3 0.3 0.0018 18.9 0.0 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain YpjP PF14005.6 RUS74192.1 - 3.9 7.5 16.8 1.7 8.7 8.4 2.6 1 1 1 2 2 2 0 YpjP-like protein TetR_C_35 PF18556.1 RUS74192.1 - 8.5 6.6 6.8 9.6 6.4 1.7 3.2 2 1 1 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain DUF1619 PF07773.11 RUS74193.1 - 3.7e-63 214.4 12.5 3.1e-60 204.8 11.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) OAD_gamma PF04277.13 RUS74195.1 - 0.0069 17.0 4.7 5.4 7.7 0.0 2.3 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DUF898 PF05987.13 RUS74195.1 - 0.0075 15.4 0.7 0.0097 15.0 0.7 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF3810 PF12725.7 RUS74195.1 - 0.024 14.0 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Pex24p PF06398.11 RUS74195.1 - 4.5 6.1 8.4 30 3.4 0.0 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Comm PF15957.5 RUS74195.1 - 7.9 6.9 0.0 7.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Commissureless PRA1 PF03208.19 RUS74195.1 - 8.5 6.0 10.0 27 4.4 9.8 1.8 1 1 1 2 2 2 0 PRA1 family protein CopK PF11525.8 RUS74196.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Copper resistance protein K Oxysterol_BP PF01237.18 RUS74197.1 - 3.6e-83 279.4 0.0 5.6e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 RUS74197.1 - 0.019 15.5 1.3 0.93 10.0 0.1 3.0 3 0 0 3 3 3 0 PH domain UPF0669 PF17065.5 RUS74197.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Aconitase_C PF00694.19 RUS74198.1 - 0.00013 22.2 1.7 58 4.0 0.0 5.2 1 1 7 8 8 8 1 Aconitase C-terminal domain Yae1_N PF09811.9 RUS74198.1 - 0.002 17.8 0.0 2.9e+02 1.3 0.0 6.7 8 0 0 8 8 8 0 Essential protein Yae1, N terminal DUF2018 PF09442.10 RUS74198.1 - 0.01 16.8 0.1 1.4e+02 3.6 0.0 5.0 1 1 9 10 10 10 0 Domain of unknown function (DUF2018) CUB PF00431.20 RUS74199.1 - 0.036 14.4 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 CUB domain Man-6-P_recep PF02157.15 RUS74200.1 - 0.22 10.6 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Nop14 PF04147.12 RUS74201.1 - 0.032 12.5 11.7 0.053 11.7 11.7 1.4 1 0 0 1 1 1 0 Nop14-like family WWE PF02825.20 RUS74201.1 - 0.13 12.8 0.0 1.4 9.5 0.0 2.3 1 1 0 1 1 1 0 WWE domain PPP4R2 PF09184.11 RUS74201.1 - 0.5 9.9 12.2 0.61 9.6 12.2 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS74201.1 - 0.5 9.6 28.6 0.74 9.1 28.6 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 RUS74201.1 - 6.1 6.5 8.5 9.6 5.9 8.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 RUS74201.1 - 6.2 4.8 33.1 8.6 4.3 33.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mur_ligase_M PF08245.12 RUS74202.1 - 1e-05 25.6 0.1 8.9e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RUS74202.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Gp_dh_C PF02800.20 RUS74203.1 - 7.4e-67 223.9 0.0 1e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RUS74203.1 - 2.2e-35 121.0 0.2 6.3e-35 119.6 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 RUS74203.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RUS74203.1 - 0.084 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 RUS74204.1 - 1.3e-35 121.7 0.0 2.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 RUS74204.1 - 2.8e-35 121.2 0.0 4.4e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 RUS74204.1 - 0.025 14.0 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HLH PF00010.26 RUS74205.1 - 0.0047 16.9 0.1 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain EF-hand_6 PF13405.6 RUS74206.1 - 4.9e-18 63.5 14.2 2e-05 24.1 0.4 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RUS74206.1 - 3.3e-17 62.7 11.8 2.5e-08 34.2 0.7 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS74206.1 - 7.3e-16 56.5 14.0 2.3e-06 26.8 1.5 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RUS74206.1 - 2.4e-13 49.7 10.3 5e-09 35.9 2.6 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS74206.1 - 2.9e-11 42.3 11.4 0.00045 19.6 1.5 4.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 RUS74206.1 - 3e-05 24.3 3.0 0.0012 19.1 0.3 2.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region GH-E PF14410.6 RUS74206.1 - 0.037 14.4 0.2 16 6.0 0.1 3.2 2 2 1 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues p25-alpha PF05517.12 RUS74206.1 - 0.042 14.0 0.1 0.11 12.7 0.0 1.8 1 1 1 2 2 2 0 p25-alpha EF-hand_4 PF12763.7 RUS74206.1 - 0.17 11.9 3.9 0.33 10.9 0.1 2.7 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RUS74206.1 - 0.43 10.9 3.2 21 5.5 0.0 3.4 2 1 1 3 3 3 0 EF-hand domain CENP-C_C PF11699.8 RUS74207.1 - 4.3e-15 55.7 0.2 1.1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 RUS74207.1 - 0.0021 17.7 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DUF2691 PF10903.8 RUS74208.1 - 0.004 17.0 0.4 2.9 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2691) Syntaxin_2 PF14523.6 RUS74209.1 - 1.6e-29 102.2 12.6 1.6e-29 102.2 12.6 2.5 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 RUS74209.1 - 1.2e-17 63.6 1.8 2.4e-17 62.7 0.1 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 RUS74209.1 - 1.5e-14 54.1 15.2 2.4e-14 53.5 15.2 1.2 1 0 0 1 1 1 1 Syntaxin DUF2207 PF09972.9 RUS74209.1 - 0.044 12.5 0.1 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMCO5 PF14992.6 RUS74209.1 - 0.053 13.1 0.2 0.053 13.1 0.2 2.3 2 0 0 2 2 2 0 TMCO5 family DUF4988 PF16378.5 RUS74209.1 - 0.068 12.8 0.5 0.068 12.8 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function Synaptobrevin PF00957.21 RUS74209.1 - 0.14 11.9 7.4 0.24 11.2 0.2 3.1 2 1 0 2 2 2 0 Synaptobrevin FUSC PF04632.12 RUS74209.1 - 0.25 9.8 2.3 0.39 9.2 2.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Caprin-1_dimer PF18293.1 RUS74209.1 - 0.3 11.6 6.0 0.067 13.7 2.2 1.8 2 0 0 2 2 2 0 Caprin-1 dimerization domain TMF_TATA_bd PF12325.8 RUS74209.1 - 0.36 11.1 18.4 0.15 12.3 9.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SAS4 PF15460.6 RUS74209.1 - 1.3 9.2 8.0 0.45 10.6 4.5 2.1 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 BORCS7 PF16088.5 RUS74209.1 - 5.8 7.2 11.1 4.5 7.6 2.2 3.0 2 2 1 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF2203 PF09969.9 RUS74209.1 - 9 7.0 9.6 32 5.3 0.3 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RFX_DNA_binding PF02257.15 RUS74210.1 - 1.3e-30 105.9 0.1 3.7e-30 104.4 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 RUS74210.1 - 0.0017 18.8 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like UL17 PF17640.2 RUS74211.1 - 0.046 13.7 0.2 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized UL17 Syntaxin_2 PF14523.6 RUS74212.1 - 1.1e-19 70.7 12.0 2.9e-19 69.3 8.8 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 RUS74212.1 - 3.2e-16 59.1 0.6 3.2e-16 59.1 0.6 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 RUS74212.1 - 4.5e-06 26.5 18.5 7.7e-05 22.5 18.5 2.6 1 1 0 1 1 1 1 Syntaxin Med30 PF11315.8 RUS74212.1 - 0.0026 18.0 5.4 0.0026 18.0 5.4 1.6 2 0 0 2 2 2 1 Mediator complex subunit 30 TMF_TATA_bd PF12325.8 RUS74212.1 - 0.0038 17.4 10.0 0.013 15.7 0.6 2.6 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Synaptobrevin PF00957.21 RUS74212.1 - 0.0047 16.7 1.5 0.0047 16.7 1.5 3.1 3 1 0 3 3 3 1 Synaptobrevin CwsA PF10814.8 RUS74212.1 - 0.091 12.9 0.1 0.091 12.9 0.1 2.1 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA T3SS_needle_E PF08988.10 RUS74212.1 - 0.7 10.1 0.0 0.7 10.1 0.0 4.2 4 1 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle UPF0242 PF06785.11 RUS74212.1 - 1.5 8.9 14.0 3.2 7.8 13.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 RUS74212.1 - 2.9 8.1 12.6 0.28 11.4 4.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 RUS74212.1 - 8.5 7.1 16.5 0.12 13.0 1.5 3.1 3 1 1 4 4 4 0 SlyX G-patch PF01585.23 RUS74213.1 - 3.4e-14 52.4 4.3 4.7e-14 52.0 4.3 1.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RUS74213.1 - 1.3e-06 28.4 3.5 2.3e-06 27.6 3.5 1.3 1 0 0 1 1 1 1 G-patch domain TFIIA PF03153.13 RUS74215.1 - 0.31 11.0 18.9 0.49 10.3 18.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 RUS74215.1 - 0.54 8.5 4.9 0.75 8.0 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SKA1 PF07160.12 RUS74215.1 - 1.3 8.8 9.6 2.1 8.1 9.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PIEZO PF15917.5 RUS74215.1 - 2.3 7.6 11.6 3.9 6.9 11.6 1.3 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 RUS74215.1 - 4 6.1 6.1 7.5 5.2 6.1 1.4 1 0 0 1 1 1 0 Presenilin PCSK9_C1 PF18459.1 RUS74216.1 - 0.054 13.6 0.1 0.054 13.6 0.1 1.6 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain CHB_HEX PF03173.13 RUS74217.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 Putative carbohydrate binding domain PCI PF01399.27 RUS74218.1 - 3.2e-12 46.9 4.0 3.2e-12 46.9 4.0 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 RUS74218.1 - 0.00021 20.9 1.3 0.00055 19.6 1.3 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Acylphosphatase PF00708.18 RUS74218.1 - 0.11 12.9 0.5 0.32 11.4 0.5 1.8 1 0 0 1 1 1 0 Acylphosphatase Ldl_recept_b PF00058.17 RUS74219.1 - 3.3e-139 453.2 33.5 5.2e-10 39.7 0.0 19.5 19 1 0 19 19 19 18 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 RUS74219.1 - 1.4e-29 102.0 80.8 5e-11 42.7 5.1 5.5 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 RUS74219.1 - 1.4e-19 70.0 39.6 1.8e-11 44.0 11.1 3.7 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SGL PF08450.12 RUS74219.1 - 7.4e-14 51.9 11.2 0.29 10.7 0.0 9.1 6 2 3 9 9 9 5 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 RUS74219.1 - 0.0034 17.3 22.0 0.19 11.7 0.0 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like SL4P PF17618.2 RUS74219.1 - 0.66 10.1 12.2 81 3.4 0.0 7.8 9 0 0 9 9 9 0 Uncharacterized Strongylid L4 protein DUF4551 PF15087.6 RUS74219.1 - 1.3 7.8 0.0 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) zf-LITAF-like PF10601.9 RUS74220.1 - 6.6e-16 58.3 17.3 8.5e-16 58.0 17.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF1057 PF06342.12 RUS74221.1 - 1.8e-08 33.8 0.0 2.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 RUS74221.1 - 0.00041 21.0 0.3 0.00056 20.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metal_resist PF13801.6 RUS74223.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Heavy-metal resistance PH PF00169.29 RUS74225.1 - 1.5e-13 51.1 0.4 5.2e-13 49.4 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS74225.1 - 0.0025 18.2 0.6 0.0083 16.5 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RUS74225.1 - 0.0041 17.4 0.4 0.01 16.1 0.4 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain VPS9 PF02204.18 RUS74225.1 - 0.014 15.6 0.0 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain DUF5128 PF17170.4 RUS74225.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller Fasciclin PF02469.22 RUS74227.1 - 2.3e-26 92.5 0.0 3.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 RUS74228.1 - 3.7e-56 188.8 0.1 4.1e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Fasciclin domain DUF2228 PF10228.9 RUS74230.1 - 2.1e-76 257.0 0.0 3.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) zf-CCHH PF10283.9 RUS74230.1 - 1.4e-11 44.1 7.8 1.4e-11 44.1 7.8 2.1 2 0 0 2 2 2 1 PBZ domain DUF2229 PF09989.9 RUS74230.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Ank_2 PF12796.7 RUS74231.1 - 3.3e-19 69.3 4.3 2.1e-11 44.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74231.1 - 2.9e-16 59.6 3.7 1.1e-08 35.5 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS74231.1 - 2.4e-15 55.1 0.7 0.0076 16.7 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 RUS74231.1 - 1.9e-13 50.4 3.2 4.2e-09 36.5 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS74231.1 - 8e-12 45.0 7.6 0.00084 19.7 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeat BESS PF02944.20 RUS74232.1 - 0.0074 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 BESS motif DndE PF08870.11 RUS74233.1 - 0.084 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 DNA sulphur modification protein DndE TMEM144 PF07857.12 RUS74234.1 - 2.4e-91 306.2 11.7 2.9e-91 305.9 11.7 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 RUS74234.1 - 1.1e-07 31.5 1.2 1.1e-07 31.5 1.2 2.6 3 0 0 3 3 3 1 Sugar transport protein CS PF04969.16 RUS74235.1 - 7.6e-12 46.1 0.4 1.1e-11 45.6 0.4 1.2 1 0 0 1 1 1 1 CS domain SDA1 PF05285.12 RUS74236.1 - 2.6e-69 234.3 47.6 1.8e-38 132.9 11.4 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 RUS74236.1 - 8e-20 70.9 1.1 2.5e-19 69.3 0.3 2.5 2 0 0 2 2 2 1 NUC130/3NT domain YL1 PF05764.13 RUS74236.1 - 3.7 7.6 36.3 2.7 8.0 3.9 2.4 2 0 0 2 2 2 0 YL1 nuclear protein zf-C3HC4_2 PF13923.6 RUS74237.1 - 6.8e-08 32.2 9.5 1.2e-07 31.4 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS74237.1 - 4.3e-07 29.7 9.0 7.6e-07 28.9 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS74237.1 - 5.7e-07 29.8 9.7 1e-06 29.0 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS74237.1 - 3.3e-05 23.7 9.3 6e-05 22.8 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS74237.1 - 0.00012 22.0 6.8 0.00032 20.7 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS74237.1 - 0.00077 19.3 8.7 0.0014 18.4 8.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Atg14 PF10186.9 RUS74237.1 - 0.0018 17.4 12.1 0.005 16.0 12.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-P11 PF03854.14 RUS74237.1 - 0.0021 17.7 6.6 0.0045 16.6 6.6 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 RUS74237.1 - 0.0023 18.1 6.4 0.0058 16.9 6.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS74237.1 - 0.0053 16.7 8.0 0.011 15.6 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain SlyX PF04102.12 RUS74237.1 - 0.0059 17.2 0.8 0.0059 17.2 0.8 3.1 3 0 0 3 3 3 1 SlyX YabA PF06156.13 RUS74237.1 - 0.012 16.2 16.7 4.3 8.0 11.8 3.6 2 1 0 2 2 2 0 Initiation control protein YabA XLF PF09302.11 RUS74237.1 - 0.031 14.4 2.7 0.096 12.8 2.7 1.8 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Tam41_Mmp37 PF09139.11 RUS74237.1 - 0.15 11.5 4.8 0.29 10.5 4.8 1.5 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Zn_ribbon_17 PF17120.5 RUS74237.1 - 0.55 9.9 5.5 1 9.0 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RUS74237.1 - 1.2 9.3 9.6 2.6 8.3 9.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Tropomyosin_1 PF12718.7 RUS74237.1 - 2.3 8.4 21.8 21 5.2 16.5 3.2 2 1 0 2 2 2 0 Tropomyosin like DivIC PF04977.15 RUS74237.1 - 3.6 7.4 20.8 1.4 8.7 1.8 3.4 3 0 0 3 3 3 0 Septum formation initiator GAS PF13851.6 RUS74237.1 - 4.1 6.7 20.6 0.071 12.5 12.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lig_chan PF00060.26 RUS74238.1 - 4.8e-39 133.6 0.3 6.2e-39 133.2 0.3 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS74238.1 - 1.4e-36 125.2 0.0 2.6e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS74238.1 - 3.9e-18 65.7 0.0 6.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PhoR PF11808.8 RUS74238.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.3 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR DUF1189 PF06691.11 RUS74238.1 - 0.2 11.2 2.6 0.23 11.0 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) RVT_1 PF00078.27 RUS74240.1 - 1.3e-30 106.6 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lig_chan PF00060.26 RUS74241.1 - 1.6e-41 141.6 0.3 2.3e-41 141.1 0.3 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS74241.1 - 3.4e-38 130.4 0.0 5.9e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS74241.1 - 1.6e-18 67.0 0.0 2.9e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 U6-snRNA_bdg PF10596.9 RUS74241.1 - 0.055 13.4 0.2 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 DUF3367 PF11847.8 RUS74241.1 - 0.22 9.4 1.3 1.2 6.9 1.3 1.9 1 1 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase CX9C PF16860.5 RUS74243.1 - 0.082 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, EGF_2 PF07974.13 RUS74243.1 - 0.13 12.7 1.9 0.27 11.6 1.9 1.6 1 1 0 1 1 1 0 EGF-like domain Glyco_hydro81C PF17652.1 RUS74245.1 - 1.3e-56 192.3 0.1 2.5e-56 191.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 RUS74245.1 - 1.1e-08 34.7 0.0 5.9e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain 7tm_1 PF00001.21 RUS74246.1 - 0.0011 18.4 1.9 0.0016 17.8 1.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS74247.1 - 0.049 12.9 8.6 0.13 11.6 8.4 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) FSA_C PF10479.9 RUS74247.1 - 1.8 6.6 15.7 2.2 6.3 15.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus 7TM_GPCR_Srw PF10324.9 RUS74247.1 - 2.2 7.5 15.3 11 5.2 15.3 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw AKAP7_NLS PF10469.9 RUS74248.1 - 1.1e-57 195.3 0.0 1.3e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 RUS74248.1 - 3e-11 43.0 0.7 6.6e-11 41.9 0.7 1.5 1 0 0 1 1 1 1 KH domain 2_5_RNA_ligase2 PF13563.6 RUS74248.1 - 0.00072 19.5 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily KH_2 PF07650.17 RUS74248.1 - 0.026 14.3 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 KH domain Ribosomal_L6 PF00347.23 RUS74248.1 - 0.13 13.0 0.5 0.23 12.2 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L6 SR-25 PF10500.9 RUS74249.1 - 0.0043 16.7 10.8 0.0043 16.7 10.8 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Neugrin PF06413.11 RUS74249.1 - 0.036 14.1 7.5 0.069 13.1 7.5 1.4 1 0 0 1 1 1 0 Neugrin CSRNP_N PF16019.5 RUS74249.1 - 0.5 10.3 12.2 0.98 9.3 12.2 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Spt20 PF12090.8 RUS74249.1 - 1.1 8.9 26.9 2.2 7.8 26.9 1.5 1 0 0 1 1 1 0 Spt20 family CCSAP PF15748.5 RUS74249.1 - 2 8.5 19.8 0.23 11.6 15.2 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Spem1 PF15670.5 RUS74249.1 - 6.7 6.2 18.4 0.26 10.8 12.4 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 PAT1 PF09770.9 RUS74249.1 - 7.6 4.7 21.3 14 3.8 21.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 RUS74249.1 - 7.8 5.1 13.2 13 4.4 13.2 1.3 1 0 0 1 1 1 0 Presenilin Fis1_TPR_C PF14853.6 RUS74250.1 - 1.6e-19 69.7 1.2 2.5e-19 69.1 1.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 RUS74250.1 - 1e-09 37.9 0.5 1.8e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RUS74250.1 - 7.3e-05 22.9 0.7 0.00021 21.5 0.2 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RUS74250.1 - 0.0014 18.6 0.2 0.004 17.1 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.8 RUS74250.1 - 0.0026 16.8 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 RUS74250.1 - 0.0041 17.8 0.1 0.0095 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74250.1 - 0.0054 16.5 0.2 0.015 15.1 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1672 PF07901.11 RUS74250.1 - 0.0057 16.0 0.5 0.0073 15.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) TPR_8 PF13181.6 RUS74250.1 - 0.0087 16.2 0.7 0.028 14.6 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS74250.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Mucin2_WxxW PF13330.6 RUS74251.1 - 1.6e-14 54.4 0.5 1.6e-14 54.4 0.5 2.7 3 0 0 3 3 3 1 Mucin-2 protein WxxW repeating region DUF775 PF05603.12 RUS74251.1 - 0.021 14.4 2.9 0.024 14.2 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF775) SUIM_assoc PF16619.5 RUS74251.1 - 0.024 14.7 8.1 0.1 12.7 8.0 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EphA2_TM PF14575.6 RUS74251.1 - 0.029 15.2 2.4 12 6.9 0.0 3.8 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SPX PF03105.19 RUS74251.1 - 0.17 11.8 8.2 0.26 11.2 8.2 1.4 1 0 0 1 1 1 0 SPX domain OMPdecase PF00215.24 RUS74251.1 - 0.98 9.0 2.6 6 6.4 0.1 2.1 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family HemY_N PF07219.13 RUS74251.1 - 2.5 8.3 6.0 6.7 7.0 6.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Spt20 PF12090.8 RUS74251.1 - 3 7.4 14.8 7.8 6.0 14.8 1.6 1 1 0 1 1 1 0 Spt20 family F420_oxidored PF03807.17 RUS74254.1 - 8.3e-14 51.9 0.1 2.8e-13 50.3 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 RUS74254.1 - 1.8e-05 24.9 8.5 1.8e-05 24.9 8.5 2.9 1 1 2 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 RUS74254.1 - 7.2e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 RUS74254.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 RUS74254.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RUS74254.1 - 0.019 15.4 0.5 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding PDH PF02153.17 RUS74254.1 - 0.024 13.7 0.1 0.057 12.4 0.0 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 RUS74254.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 RUS74254.1 - 0.14 12.1 0.2 16 5.4 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cu-oxidase PF00394.22 RUS74255.1 - 8e-32 110.6 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 RUS74255.1 - 1.9e-25 89.2 0.9 1e-23 83.6 0.5 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RUS74255.1 - 1.4e-09 37.8 0.6 0.00037 20.3 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase LMWPc PF01451.21 RUS74255.1 - 0.043 14.2 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Ctr PF04145.15 RUS74256.1 - 0.0059 17.2 1.8 0.0076 16.9 1.8 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF5102 PF17104.5 RUS74256.1 - 0.011 15.7 3.6 0.012 15.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Apt1 PF10351.9 RUS74256.1 - 0.038 12.9 14.5 0.034 13.0 14.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CbtB PF09489.10 RUS74256.1 - 0.12 12.4 0.2 0.29 11.3 0.2 1.6 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Peroxin-3 PF04882.12 RUS74256.1 - 0.87 8.5 9.8 0.9 8.5 9.8 1.1 1 0 0 1 1 1 0 Peroxin-3 DUF1180 PF06679.12 RUS74256.1 - 1.1 9.6 5.0 1.4 9.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 RUS74256.1 - 2.4 6.6 20.3 2.4 6.6 20.3 1.1 1 0 0 1 1 1 0 Macoilin family Period_C PF12114.8 RUS74256.1 - 2.5 7.6 25.4 2.7 7.6 25.4 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4614 PF15391.6 RUS74256.1 - 2.9 7.9 27.0 3.4 7.6 27.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sec3_C PF09763.9 RUS74256.1 - 6 5.1 9.6 5.6 5.2 9.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 LRR_8 PF13855.6 RUS74257.1 - 5.6e-37 125.3 33.2 1.7e-11 43.7 1.5 8.8 6 1 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 RUS74257.1 - 4.5e-16 58.7 55.6 0.00019 21.7 0.0 11.5 7 3 6 14 14 14 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 RUS74257.1 - 1.1e-14 55.0 0.0 3.5e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS74257.1 - 1.4e-11 44.5 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 RUS74257.1 - 9.3e-06 25.6 14.6 0.064 13.2 3.6 4.7 3 2 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS74257.1 - 0.00025 20.6 19.0 0.039 13.5 0.2 4.9 4 1 1 5 5 5 3 Leucine-rich repeat Herpes_U34 PF04541.13 RUS74257.1 - 0.054 12.7 0.1 0.15 11.3 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus virion protein U34 DUF1863 PF08937.11 RUS74257.1 - 0.096 13.0 0.3 0.5 10.7 0.3 2.3 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Pentapeptide_4 PF13599.6 RUS74257.1 - 0.23 11.6 3.7 1.5 9.1 1.2 2.8 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_8 PF13855.6 RUS74258.1 - 7.8e-32 108.8 55.0 1e-11 44.4 1.8 9.0 7 2 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 RUS74258.1 - 7.3e-15 54.8 75.8 4.2e-06 27.0 1.1 12.0 6 3 8 14 14 14 9 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 RUS74258.1 - 3.5e-10 40.5 0.0 6.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS74258.1 - 9.9e-09 35.2 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 RUS74258.1 - 8.5e-06 25.4 22.9 0.0096 15.4 3.6 5.0 4 2 2 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 RUS74258.1 - 0.28 11.9 49.9 8.6 7.4 1.6 12.7 11 4 1 12 12 12 0 Leucine Rich Repeat Antistasin PF02822.14 RUS74259.1 - 3.1e-06 27.7 21.0 4e-06 27.3 7.5 2.4 2 1 0 2 2 2 2 Antistasin family Neur_chan_LBD PF02931.23 RUS74260.1 - 2.8e-62 210.0 2.6 3.6e-62 209.6 2.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74260.1 - 8.8e-31 107.8 0.0 1.1e-30 107.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FAD_binding_8 PF08022.12 RUS74261.1 - 1.7e-20 73.1 0.0 5.1e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RUS74261.1 - 1.7e-15 57.3 9.9 3.4e-15 56.3 9.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.6 RUS74261.1 - 4.1e-10 38.7 5.3 0.091 12.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RUS74261.1 - 5.1e-10 39.7 6.4 3e-06 27.6 0.4 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS74261.1 - 1.9e-09 36.4 5.6 0.015 14.8 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS74261.1 - 8.1e-05 22.4 5.6 0.11 12.3 0.9 3.6 1 1 2 3 3 3 2 EF-hand domain pair NAD_binding_6 PF08030.12 RUS74261.1 - 0.0026 17.9 0.0 0.0057 16.8 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_5 PF13202.6 RUS74261.1 - 0.0028 17.1 6.9 0.24 10.9 0.0 3.4 4 0 0 4 4 4 2 EF hand FAD_binding_6 PF00970.24 RUS74261.1 - 0.073 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain PRESAN PF09687.10 RUS74261.1 - 0.17 12.4 0.5 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal DUF1236 PF06823.12 RUS74262.1 - 0.00016 21.4 0.6 2 8.3 0.0 3.9 1 1 3 4 4 4 1 Protein of unknown function (DUF1236) Nse4_C PF08743.10 RUS74262.1 - 0.012 15.9 0.0 19 5.6 0.0 3.7 1 1 1 2 2 2 0 Nse4 C-terminal Coilin_N PF15862.5 RUS74262.1 - 0.021 14.6 1.8 0.049 13.4 0.8 1.8 1 1 1 2 2 2 0 Coilin N-terminus Autophagy_N PF03986.13 RUS74262.1 - 0.064 13.2 0.8 4.8 7.1 0.1 2.3 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain FhuF_C PF11575.8 RUS74262.1 - 0.097 12.6 4.6 45 4.1 0.0 5.1 4 2 1 5 5 5 0 FhuF 2Fe-2S C-terminal domain Ground-like PF04155.18 RUS74262.1 - 0.11 13.2 9.8 11 6.7 0.1 4.0 1 1 4 5 5 5 0 Ground-like domain SecA_PP_bind PF01043.20 RUS74262.1 - 0.27 11.9 6.2 1.6e+02 3.0 6.2 3.5 1 1 0 1 1 1 0 SecA preprotein cross-linking domain Fibroin_P25 PF07294.11 RUS74262.1 - 0.58 10.2 7.4 0.35 10.9 4.5 1.8 1 1 1 2 2 2 0 Fibroin P25 DUF4528 PF15031.6 RUS74262.1 - 9.9 6.2 10.9 11 6.1 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4528) EPTP PF03736.17 RUS74263.1 - 6.3e-62 205.3 16.9 9.9e-15 54.3 0.1 7.8 7 1 0 7 7 7 7 EPTP domain DUF2457 PF10446.9 RUS74263.1 - 3.8 6.5 25.1 5.7 6.0 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 RUS74263.1 - 7.7 4.9 7.2 11 4.5 7.2 1.1 1 0 0 1 1 1 0 Utp14 protein MIF4G PF02854.19 RUS74264.1 - 0.19 11.3 4.2 4.2 6.9 1.7 2.3 1 1 1 2 2 2 0 MIF4G domain MCPsignal PF00015.21 RUS74264.1 - 2 8.2 14.1 15 5.3 12.9 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain p450 PF00067.22 RUS74265.1 - 7.1e-72 242.6 0.0 2.8e-55 187.9 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 RUS74266.1 - 1.4e-76 258.1 0.0 2.2e-76 257.5 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 SDA1 PF05285.12 RUS74267.1 - 0.00096 18.7 28.9 0.0011 18.5 28.9 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS74267.1 - 0.002 16.5 32.7 0.0022 16.3 32.7 1.0 1 0 0 1 1 1 1 Nop14-like family LRR_10 PF18805.1 RUS74267.1 - 0.013 15.1 0.0 6.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat Mpp10 PF04006.12 RUS74267.1 - 0.11 10.9 24.7 0.12 10.8 24.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 RUS74267.1 - 0.4 9.4 9.0 0.51 9.1 9.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 RUS74267.1 - 0.96 8.8 25.3 1.3 8.3 25.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 RUS74267.1 - 1.4 8.7 6.0 1.6 8.6 6.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop25 PF09805.9 RUS74267.1 - 4.9 7.6 13.8 7.2 7.1 13.8 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NPR3 PF03666.13 RUS74267.1 - 6.6 5.4 5.6 7.1 5.3 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS74267.1 - 8.5 4.5 31.1 13 3.9 31.1 1.3 1 0 0 1 1 1 0 CDC45-like protein EGF PF00008.27 RUS74268.1 - 1.7e-08 34.6 7.3 9.4e-08 32.2 7.3 2.0 1 1 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 RUS74268.1 - 7.2e-08 32.5 7.3 1.3e-07 31.7 7.3 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain hEGF PF12661.7 RUS74268.1 - 1.3e-06 28.8 6.5 1.3e-06 28.8 6.5 1.7 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.13 RUS74268.1 - 0.014 15.8 11.9 0.027 14.9 11.9 1.4 1 0 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.6 RUS74268.1 - 0.047 14.0 9.0 0.093 13.0 9.0 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site VERL PF11386.8 RUS74268.1 - 0.074 13.2 1.5 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Vitelline envelope receptor for lysin DUF3439 PF11921.8 RUS74268.1 - 0.36 10.8 5.3 0.65 10.0 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EGF_3 PF12947.7 RUS74268.1 - 1.2 9.4 7.2 2.4 8.5 7.2 1.5 1 0 0 1 1 1 0 EGF domain cEGF PF12662.7 RUS74268.1 - 5.1 7.1 9.9 0.45 10.5 3.6 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like Lectin_C PF00059.21 RUS74269.1 - 1.4e-11 45.1 1.8 2.4e-10 41.1 0.1 2.7 3 0 0 3 3 3 1 Lectin C-type domain Claudin_2 PF13903.6 RUS74270.1 - 0.73 9.5 14.6 0.16 11.7 6.5 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Proton_antipo_N PF00662.20 RUS74270.1 - 0.83 9.8 3.8 1.6 8.9 0.3 2.5 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF2970 PF11174.8 RUS74270.1 - 2.7 7.9 9.8 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Polysacc_synt_C PF14667.6 RUS74270.1 - 3.5 7.7 14.8 0.81 9.7 8.5 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain FtsX PF02687.21 RUS74270.1 - 7.2 7.2 14.4 23 5.5 3.6 2.6 1 1 1 2 2 2 0 FtsX-like permease family Claudin_2 PF13903.6 RUS74271.1 - 0.00028 20.7 3.9 0.0022 17.8 3.9 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 RUS74271.1 - 0.0025 18.1 2.1 0.0059 16.8 2.1 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF5453 PF17534.2 RUS74271.1 - 0.12 12.3 3.2 0.17 11.8 2.8 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5453) Wzy_C_2 PF11846.8 RUS74271.1 - 1.9 8.4 5.5 3.6 7.5 0.0 2.6 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Alpha-amylase PF00128.24 RUS74272.1 - 2.2e-56 191.9 1.7 3.1e-56 191.4 1.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 RUS74272.1 - 5.1e-30 102.9 0.2 1.2e-29 101.6 0.2 1.6 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus RR_TM4-6 PF06459.12 RUS74273.1 - 1.3e-40 140.1 0.0 2.3e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 RIH_assoc PF08454.11 RUS74273.1 - 1.3e-30 105.3 0.4 4.4e-30 103.5 0.1 2.1 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RUS74273.1 - 1.1e-13 51.0 8.2 1.1e-13 51.0 8.2 3.5 4 0 0 4 4 4 1 Ion transport protein EF-hand_7 PF13499.6 RUS74273.1 - 9.4e-12 45.2 0.6 2.8e-11 43.7 0.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS74273.1 - 1e-10 40.4 6.9 1.7e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RUS74273.1 - 6.8e-10 38.0 0.1 0.00045 19.6 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS74273.1 - 8.8e-09 35.1 3.8 7.5e-06 25.7 0.6 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS74273.1 - 1.3e-06 27.9 5.9 0.00012 21.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain GWT1 PF06423.12 RUS74273.1 - 0.017 15.3 2.0 7.2 6.7 0.2 3.3 3 0 0 3 3 3 0 GWT1 SPARC_Ca_bdg PF10591.9 RUS74273.1 - 0.055 13.8 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region 7tm_1 PF00001.21 RUS74277.1 - 1.2e-25 90.4 17.8 1.8e-25 89.8 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS74277.1 - 6.7e-05 22.6 10.5 6.7e-05 22.6 10.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Arf PF00025.21 RUS74278.1 - 7.7e-76 253.4 0.1 8.9e-76 253.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS74278.1 - 4.4e-14 52.7 0.0 6.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS74278.1 - 2.2e-12 46.9 0.0 2.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS74278.1 - 5e-12 45.6 0.0 6.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS74278.1 - 1.1e-11 44.5 1.2 5.3e-08 32.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS74278.1 - 1.7e-10 40.7 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS74278.1 - 1.8e-06 28.0 0.1 1.6e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RUS74278.1 - 0.0034 16.7 0.4 0.01 15.1 0.4 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.25 RUS74281.1 - 1.6e-37 129.3 0.0 2.9e-37 128.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74281.1 - 7.7e-25 87.6 0.0 9.8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS74281.1 - 0.0017 17.2 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS74281.1 - 0.0032 16.9 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS74281.1 - 0.017 14.7 0.3 0.92 9.1 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sulfotransfer_2 PF03567.14 RUS74282.1 - 5.7e-20 72.3 0.5 8.8e-20 71.7 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family EGF PF00008.27 RUS74283.1 - 3.6e-15 55.9 20.2 1.7e-07 31.4 6.3 2.2 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS74283.1 - 4.4e-09 36.6 21.3 9.6e-05 22.9 5.6 2.9 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 RUS74283.1 - 3.2e-08 33.8 21.7 0.00069 19.9 6.0 2.3 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 RUS74283.1 - 0.69 10.2 12.3 1.9 8.8 2.3 2.8 1 1 1 2 2 2 0 EGF domain Laminin_EGF PF00053.24 RUS74283.1 - 0.74 10.0 17.7 2.1 8.6 5.0 2.6 1 1 1 2 2 2 0 Laminin EGF domain FXa_inhibition PF14670.6 RUS74283.1 - 1.7 9.0 18.6 6.6 7.1 5.6 2.6 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Filamin PF00630.19 RUS74284.1 - 8.9e-07 29.7 0.0 1.5e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat TPR_12 PF13424.6 RUS74285.1 - 3.8e-11 43.1 2.1 0.00038 20.7 0.7 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74285.1 - 5.3e-10 38.7 6.2 0.073 12.9 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74285.1 - 2.6e-07 30.2 8.5 0.23 11.7 0.4 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS74285.1 - 0.00011 21.8 1.9 0.00022 20.7 1.9 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 RUS74285.1 - 0.0007 19.6 2.9 2.1 8.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS74285.1 - 0.00084 19.4 1.2 0.0022 18.0 1.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 5 SMBP PF16785.5 RUS74285.1 - 0.02 15.1 1.7 0.78 10.0 0.4 2.8 2 0 0 2 2 2 0 Small metal-binding protein TPR_10 PF13374.6 RUS74285.1 - 0.025 14.5 0.6 4.5 7.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS74285.1 - 0.27 11.4 1.0 5.2 7.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74286.1 - 3.5e-07 29.7 5.7 0.00031 20.4 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74286.1 - 1e-06 28.4 4.8 0.00034 20.5 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS74286.1 - 0.0011 19.6 0.2 0.0077 17.0 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS74286.1 - 0.034 14.8 1.0 14 6.4 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS74286.1 - 0.078 13.3 1.2 4.3 7.7 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS74286.1 - 0.17 12.2 3.3 0.46 10.8 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Gal-bind_lectin PF00337.22 RUS74287.1 - 6.8e-17 61.3 0.0 7e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Galactoside-binding lectin ATP-synt_S1 PF05827.12 RUS74288.1 - 0.0045 16.8 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) RNA_pol_Rpb8 PF03870.15 RUS74290.1 - 5.7e-37 127.0 0.0 6.3e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 RUS74290.1 - 0.00038 20.5 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G Dor1 PF04124.12 RUS74291.1 - 1.5e-123 411.8 0.2 1.9e-123 411.5 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 RUS74291.1 - 0.00093 17.9 0.8 0.0015 17.2 0.8 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps51 PF08700.11 RUS74291.1 - 0.011 15.8 0.0 0.04 14.0 0.0 2.1 1 0 0 1 1 1 0 Vps51/Vps67 ATP-synt_ab PF00006.25 RUS74292.1 - 1.3e-107 358.3 0.0 2e-107 357.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 RUS74292.1 - 3.8e-45 152.6 0.0 6.9e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Homeobox_KN PF05920.11 RUS74293.1 - 0.023 14.6 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain TFIIA PF03153.13 RUS74293.1 - 0.11 12.5 9.2 0.013 15.6 4.8 1.6 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit RCDG1 PF15725.5 RUS74293.1 - 4.5 7.8 9.8 8.3 6.9 5.5 3.0 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein CCDC53 PF10152.9 RUS74293.1 - 9.9 6.6 11.1 2.3 8.6 4.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex fn3 PF00041.21 RUS74294.1 - 2.8e-39 133.4 4.5 1.6e-19 70.0 0.8 3.4 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS74294.1 - 8e-06 26.3 3.7 0.09 13.4 1.0 3.8 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RUS74294.1 - 0.031 14.6 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 RUS74294.1 - 0.057 13.4 0.0 2 8.4 0.0 3.2 3 1 0 3 3 3 0 Fibronectin-III type domain fn3_2 PF16893.5 RUS74294.1 - 0.088 13.0 0.1 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Fibronectin type III domain DUF4381 PF14316.6 RUS74294.1 - 0.96 9.7 2.8 0.66 10.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) I-set PF07679.16 RUS74295.1 - 1.7e-39 133.8 0.0 1.9e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74295.1 - 8e-34 116.1 0.0 9.6e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS74295.1 - 5.6e-21 74.7 1.0 4.6e-09 36.4 0.3 3.9 2 2 1 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 RUS74295.1 - 2.5e-20 72.4 0.0 9.4e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS74295.1 - 8.7e-20 70.9 0.0 6.7e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS74295.1 - 3.4e-07 30.3 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS74295.1 - 5.6e-07 29.0 0.0 0.0096 15.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 RUS74295.1 - 2.3e-05 24.5 0.0 0.064 13.5 0.0 2.4 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS74295.1 - 3.1e-05 24.3 0.0 0.013 15.8 0.0 2.6 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 RUS74295.1 - 0.00028 19.8 0.0 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 RUS74295.1 - 0.00052 20.0 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain CBM_20 PF00686.19 RUS74295.1 - 0.12 12.3 0.0 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Starch binding domain Ig_3 PF13927.6 RUS74296.1 - 1.1e-22 80.3 0.8 2.3e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS74296.1 - 1.2e-22 79.8 0.1 3.9e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS74296.1 - 1.5e-13 50.9 0.1 6.7e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS74296.1 - 1.7e-13 50.5 0.2 1.3e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS74296.1 - 1e-08 35.1 0.1 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS74296.1 - 0.00019 21.6 1.3 0.73 10.0 0.2 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.15 RUS74296.1 - 0.0011 19.3 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 RUS74296.1 - 0.086 12.9 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family 7tm_1 PF00001.21 RUS74298.1 - 1e-15 57.8 11.2 1.6e-15 57.2 11.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PSI_8 PF00796.18 RUS74298.1 - 0.0048 16.7 1.1 0.015 15.1 1.1 2.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VIII 7TM_GPCR_Srsx PF10320.9 RUS74298.1 - 0.55 9.6 15.6 1.5 8.1 15.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Neur_chan_LBD PF02931.23 RUS74299.1 - 1.9e-35 122.3 0.2 2.5e-35 121.9 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74299.1 - 2e-13 51.0 1.4 2.5e-13 50.6 1.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS74301.1 - 1e-46 159.1 3.5 1.5e-46 158.6 3.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74301.1 - 3.9e-24 86.0 8.1 5.9e-24 85.4 8.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 7TM_GPCR_Srw PF10324.9 RUS74302.1 - 0.011 15.1 6.0 0.014 14.7 6.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS74302.1 - 0.017 14.4 10.9 0.024 14.0 10.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS74302.1 - 0.071 12.7 13.9 0.095 12.3 13.9 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx UPF0715 PF17094.5 RUS74302.1 - 0.38 11.3 9.1 0.14 12.7 6.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0715) CobT PF06213.12 RUS74302.1 - 0.99 8.7 11.9 1.3 8.4 11.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.11 RUS74302.1 - 2.6 7.5 15.5 3.4 7.2 15.5 1.1 1 0 0 1 1 1 0 PPP4R2 Pes-10 PF07149.11 RUS74302.1 - 6.1 5.8 11.9 7.2 5.5 11.9 1.1 1 0 0 1 1 1 0 Pes-10 Somatomedin_B PF01033.17 RUS74303.1 - 6.6e-05 23.2 13.0 6.6e-05 23.2 13.0 2.4 2 0 0 2 2 2 1 Somatomedin B domain IgGFc_binding PF17517.2 RUS74304.1 - 4.8e-09 35.9 0.1 0.00071 19.0 0.0 2.3 2 0 0 2 2 2 2 IgGFc binding protein DAO PF01266.24 RUS74305.1 - 2.6e-17 63.5 0.0 6.5e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Med15 PF09606.10 RUS74306.1 - 1.9e-06 26.9 0.0 2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 RUS74306.1 - 0.0034 17.4 0.3 0.0045 16.9 0.3 1.4 1 1 0 1 1 1 1 KIX domain KIX PF02172.16 RUS74306.1 - 0.15 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 KIX domain CytB6-F_Fe-S PF08802.10 RUS74307.1 - 5.6e-05 23.1 22.2 16 5.6 0.0 8.2 8 0 0 8 8 8 4 Cytochrome B6-F complex Fe-S subunit PC_rep PF01851.22 RUS74307.1 - 0.14 12.6 6.5 1.5e+02 3.1 0.1 6.0 4 1 4 8 8 8 0 Proteasome/cyclosome repeat IPTL-CTERM PF18203.1 RUS74307.1 - 1.3 9.0 18.7 93 3.1 0.1 6.3 6 0 0 6 6 6 0 IPTL-CTERM motif Hyr1 PF15789.5 RUS74307.1 - 2.6 7.7 8.1 13 5.4 0.1 4.0 2 2 1 3 3 3 0 Hyphally regulated cell wall GPI-anchored protein 1 Pkinase PF00069.25 RUS74310.1 - 4.3e-64 216.4 0.0 7.9e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74310.1 - 7.7e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 RUS74310.1 - 8.3e-12 45.4 2.1 1.9e-11 44.2 2.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 RUS74310.1 - 0.0006 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 RUS74310.1 - 0.002 18.6 0.1 0.0041 17.6 0.1 1.5 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 RUS74310.1 - 0.026 13.9 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cofilin_ADF PF00241.20 RUS74311.1 - 5.7e-14 52.0 0.0 8.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Patatin PF01734.22 RUS74313.1 - 1.7e-23 83.9 0.1 5.8e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase EF-hand_1 PF00036.32 RUS74313.1 - 8.3e-07 28.1 0.9 0.00011 21.5 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS74313.1 - 1.1e-06 28.1 0.2 0.034 14.1 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS74313.1 - 0.00038 20.3 0.4 0.0011 18.8 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS74313.1 - 0.0012 19.3 1.3 0.0012 19.3 1.3 3.7 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS74313.1 - 0.0078 15.7 0.1 0.037 13.5 0.0 2.2 2 0 0 2 2 2 1 EF hand Sec3_C PF09763.9 RUS74313.1 - 0.13 10.6 5.6 0.29 9.5 5.6 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1295 PF06966.12 RUS74314.1 - 3.3e-61 206.8 2.6 3.8e-61 206.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RUS74314.1 - 2.2e-06 27.7 2.1 5.7e-06 26.4 0.3 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 RUS74314.1 - 0.00027 21.3 0.5 0.0026 18.1 0.1 2.6 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RUS74314.1 - 0.0033 17.8 0.1 0.0033 17.8 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 RUS74314.1 - 0.0066 15.3 0.5 0.021 13.6 0.5 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family BIRC6 PF12356.8 RUS74314.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 RT_RNaseH PF17917.1 RUS74315.1 - 5.4e-21 74.9 0.1 7.6e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS74315.1 - 1.5e-13 50.6 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Cas_GSU0053 PF09617.10 RUS74315.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DUF1295 PF06966.12 RUS74316.1 - 1.5e-58 198.1 3.5 1.7e-58 197.9 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RUS74316.1 - 1.7e-06 28.1 0.6 1.7e-06 28.1 0.6 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 RUS74316.1 - 0.0029 18.0 1.1 0.041 14.3 0.0 2.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 RUS74316.1 - 0.0074 15.1 3.1 0.034 12.9 3.0 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 RUS74316.1 - 0.02 15.3 1.2 0.079 13.4 0.1 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase BIRC6 PF12356.8 RUS74316.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Peptidase_C48 PF02902.19 RUS74317.1 - 2.4e-43 148.5 3.2 5.9e-43 147.2 3.2 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 RUS74317.1 - 1.8e-05 23.7 2.0 0.0043 15.8 0.4 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase Peptidase_C5 PF00770.18 RUS74317.1 - 0.098 12.3 0.3 0.23 11.1 0.2 1.6 1 1 0 1 1 1 0 Adenovirus endoprotease LMBR1 PF04791.16 RUS74317.1 - 4.4 6.1 7.0 5.4 5.8 0.6 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 RUS74319.1 - 0.0048 16.9 5.9 0.97 9.5 0.1 2.7 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_3 PF09069.11 RUS74319.1 - 0.026 14.9 0.3 0.1 13.0 0.1 2.0 1 1 1 2 2 2 0 EF-hand DUF4446 PF14584.6 RUS74319.1 - 0.027 14.5 3.2 0.036 14.0 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) VitK2_biosynth PF02621.14 RUS74319.1 - 0.1 12.1 0.3 0.48 9.9 0.1 2.0 2 0 0 2 2 2 0 Menaquinone biosynthesis Crl PF07417.12 RUS74319.1 - 0.97 9.5 4.6 1.4 9.0 0.7 2.7 3 1 0 3 3 3 0 Sigma factor-binding transcriptional regulator Crl FapA PF03961.13 RUS74319.1 - 1.8 7.1 9.0 0.12 11.0 1.5 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Phasin PF05597.11 RUS74319.1 - 5.6 7.0 8.0 11 6.0 0.5 2.8 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EphA2_TM PF14575.6 RUS74320.1 - 0.03 15.2 0.2 0.072 14.0 0.2 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ninjurin PF04923.12 RUS74320.1 - 0.093 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Ninjurin Zip PF02535.22 RUS74320.1 - 2.9 7.0 4.8 3.3 6.8 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Podoplanin PF05808.11 RUS74320.1 - 6.6 6.8 5.5 1.2 9.3 1.7 1.6 1 1 1 2 2 2 0 Podoplanin PLAC8 PF04749.17 RUS74321.1 - 4.2e-10 40.5 11.9 7.2e-10 39.8 11.9 1.5 1 1 0 1 1 1 1 PLAC8 family Dicer_N PF17895.1 RUS74321.1 - 0.18 11.6 7.3 1.9 8.3 0.8 2.2 1 1 1 2 2 2 0 Giardia Dicer N-terminal domain Cation_ATPase_C PF00689.21 RUS74322.1 - 0.02 14.6 1.3 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus RHS PF03527.14 RUS74323.1 - 0.24 11.2 0.2 0.66 9.8 0.2 1.7 1 0 0 1 1 1 0 RHS protein I-set PF07679.16 RUS74325.1 - 1.6e-16 60.1 0.0 1.6e-16 60.1 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74325.1 - 3.7e-13 49.9 0.4 2.4e-12 47.3 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 RUS74325.1 - 8.1e-09 35.7 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS74325.1 - 3.5e-05 23.9 0.0 3.5e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS74325.1 - 0.23 11.7 0.0 0.23 11.7 0.0 4.2 3 2 2 5 5 5 0 Immunoglobulin V-set domain PfkB PF00294.24 RUS74326.1 - 2.4e-07 30.3 0.2 7.6e-06 25.4 0.3 1.9 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Indigoidine_A PF04227.12 RUS74327.1 - 3.8e-127 423.6 2.0 5.3e-127 423.1 2.0 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 RUS74327.1 - 4.8e-07 29.4 0.0 7.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2678 PF10856.8 RUS74328.1 - 0.025 14.5 2.3 0.056 13.4 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) TssN PF17555.2 RUS74328.1 - 4.3 6.7 15.0 0.093 12.1 7.1 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN DHHC PF01529.20 RUS74329.1 - 1.1e-26 93.5 10.4 2e-26 92.7 10.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2427 PF10348.9 RUS74329.1 - 0.57 10.0 4.6 0.8 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) MRP-L28 PF09812.9 RUS74330.1 - 2.7e-45 154.4 5.7 3.1e-45 154.2 5.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF3972 PF13118.6 RUS74330.1 - 0.033 14.6 0.2 0.08 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DDE_Tnp_4 PF13359.6 RUS74331.1 - 3.2e-13 49.6 0.0 5.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS74331.1 - 0.0076 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein HTH_23 PF13384.6 RUS74331.1 - 0.032 14.0 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 RUS74331.1 - 0.12 12.2 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 RUS74331.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 MarR family Myb_DNA-bind_5 PF13873.6 RUS74332.1 - 1.5e-15 57.0 1.6 2.7e-15 56.2 0.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RUS74332.1 - 1e-05 25.8 1.8 3.4e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 RUS74332.1 - 0.00019 21.7 0.3 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 RUS74332.1 - 0.12 12.6 0.3 0.38 11.0 0.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Elf1 PF05129.13 RUS74333.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PUA PF01472.20 RUS74335.1 - 7.4e-09 35.5 0.0 92 3.1 0.0 8.3 1 1 9 10 10 10 0 PUA domain Toxin_27 PF08099.11 RUS74335.1 - 1.3e-05 25.2 53.1 16 5.7 0.1 11.1 11 0 0 11 11 11 10 Scorpion calcine family Prolamin_like PF05617.11 RUS74335.1 - 2.6e-05 24.3 30.1 45 4.3 0.0 10.6 1 1 10 11 11 11 0 Prolamin-like DUF2650 PF10853.8 RUS74335.1 - 0.27 11.0 34.8 1.1e+02 2.7 0.1 10.6 11 0 0 11 11 11 0 Protein of unknown function (DUF2650) dbPDZ_assoc PF16610.5 RUS74336.1 - 0.14 12.4 1.5 0.27 11.5 1.5 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 FGF PF00167.18 RUS74337.1 - 7.4e-08 32.5 0.2 2.2e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 Fibroblast growth factor DUF1158 PF06643.11 RUS74337.1 - 0.47 11.0 1.8 0.92 10.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) EF-hand_7 PF13499.6 RUS74338.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair zf-piccolo PF05715.13 RUS74339.1 - 0.05 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger Macoilin PF09726.9 RUS74340.1 - 1.1 7.8 3.0 1.1 7.7 3.0 1.0 1 0 0 1 1 1 0 Macoilin family Colipase-like PF15083.6 RUS74342.1 - 3.6e-21 75.1 10.7 0.96 9.6 0.0 9.2 1 1 19 20 20 20 20 Colipase-like DUF1195 PF06708.11 RUS74344.1 - 8.5 6.1 19.8 38 4.0 0.3 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1195) Drf_FH1 PF06346.12 RUS74345.1 - 0.03 14.1 0.2 0.049 13.4 0.2 1.5 1 1 0 1 1 1 0 Formin Homology Region 1 Mfa_like_2 PF15415.6 RUS74347.1 - 0.0065 15.4 8.5 4.2 6.2 0.1 5.1 5 0 0 5 5 5 4 Fimbrillin-like Glyco_hydro_98C PF08307.11 RUS74347.1 - 1.6 8.1 7.7 19 4.6 0.0 4.6 5 2 2 7 7 7 0 Glycosyl hydrolase family 98 C-terminal domain DUF1622 PF07784.11 RUS74349.1 - 0.04 13.8 8.8 1.2 9.1 0.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1622) Epiglycanin_TR PF05647.11 RUS74349.1 - 0.8 9.7 50.4 5.4 7.0 20.7 3.0 1 1 1 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Nucleo_P87 PF07267.11 RUS74350.1 - 0.87 8.4 7.4 0.99 8.2 7.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Collagen PF01391.18 RUS74353.1 - 6.7e-07 29.0 22.7 0.00087 19.0 5.4 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF948 PF06103.11 RUS74353.1 - 0.7 10.2 1.6 5 7.5 0.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.16 RUS74354.1 - 1e-31 110.2 31.4 2.6e-27 95.7 19.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily AAA_16 PF13191.6 RUS74356.1 - 0.0095 16.3 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RUS74356.1 - 0.01 15.8 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 RUS74356.1 - 0.019 15.3 0.1 0.07 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RUS74356.1 - 0.027 14.4 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RUS74356.1 - 0.04 13.4 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region LRR_4 PF12799.7 RUS74356.1 - 0.33 11.4 17.3 1.7 9.2 2.2 4.7 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) OTU PF02338.19 RUS74357.1 - 5e-07 30.3 0.0 8.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease PhoLip_ATPase_C PF16212.5 RUS74359.1 - 3.1e-61 207.3 31.1 1.1e-52 179.3 25.5 3.5 3 2 1 4 4 4 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RUS74359.1 - 4e-21 74.5 1.7 4e-21 74.5 1.7 2.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RUS74359.1 - 1.9e-12 47.9 0.1 2.7e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RUS74359.1 - 6.9e-10 38.9 0.1 2.9e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RUS74359.1 - 1e-05 25.2 0.7 5.4e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RUS74359.1 - 5e-05 23.2 0.3 0.003 17.3 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3099 PF11298.8 RUS74359.1 - 6.8 6.9 6.9 30 4.8 6.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Ig_2 PF13895.6 RUS74360.1 - 6.8e-16 58.4 32.0 3.5e-06 27.3 0.3 7.6 6 1 1 7 7 7 5 Immunoglobulin domain Ig_3 PF13927.6 RUS74360.1 - 1.5e-13 51.1 40.6 8.7e-06 26.3 0.2 8.7 7 2 2 9 9 9 6 Immunoglobulin domain C2-set_2 PF08205.12 RUS74360.1 - 1.3e-10 41.2 19.4 0.0017 18.4 0.1 6.6 6 1 0 6 6 6 3 CD80-like C2-set immunoglobulin domain I-set PF07679.16 RUS74360.1 - 2.8e-06 27.3 15.0 0.0026 17.8 0.2 7.7 6 5 2 8 8 8 1 Immunoglobulin I-set domain RNA_pol_Rpb2_7 PF04560.20 RUS74360.1 - 0.026 14.9 2.1 6 7.3 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 7 DUF4064 PF13273.6 RUS74360.1 - 0.089 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) C2-set PF05790.15 RUS74360.1 - 0.11 12.7 6.5 16 5.8 0.4 5.0 5 0 0 5 5 5 0 Immunoglobulin C2-set domain NHL PF01436.21 RUS74360.1 - 5.4 7.3 7.3 4.7 7.4 1.8 3.2 2 0 0 2 2 2 0 NHL repeat DUF4493 PF14900.6 RUS74360.1 - 6.2 6.6 14.7 5.5 6.8 0.3 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF4493) I-set PF07679.16 RUS74361.1 - 0.00076 19.5 4.2 0.23 11.5 0.0 4.2 3 2 1 4 4 4 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 RUS74361.1 - 0.0049 16.9 12.9 0.0083 16.2 0.5 4.1 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain DUF3617 PF12276.8 RUS74361.1 - 0.094 13.0 1.2 6.7 7.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) GLEYA PF10528.9 RUS74361.1 - 0.14 12.6 1.1 0.51 10.8 0.1 2.4 3 0 0 3 3 3 0 GLEYA domain Na_Ca_ex PF01699.24 RUS74363.1 - 3.2e-45 153.8 26.2 2.8e-23 82.6 8.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 RUS74363.1 - 1.3e-32 111.9 1.5 1.2e-14 54.3 0.2 3.4 3 0 0 3 3 3 2 Calx-beta domain Ras PF00071.22 RUS74364.1 - 3e-39 134.2 0.0 4e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS74364.1 - 3.1e-22 79.0 0.0 5.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS74364.1 - 3.9e-07 29.7 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS74364.1 - 5.8e-05 22.6 0.0 0.00024 20.6 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS74364.1 - 0.00059 19.9 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 RUS74364.1 - 0.0027 17.2 0.1 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 RUS74364.1 - 0.046 13.6 0.2 2.4 8.1 0.1 2.3 2 1 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 RUS74364.1 - 0.054 13.4 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 RUS74364.1 - 0.079 12.7 0.2 0.22 11.2 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 RUS74364.1 - 0.093 13.0 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain 7tm_2 PF00002.24 RUS74365.1 - 2.2e-67 226.9 12.6 2.9e-67 226.5 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS74365.1 - 2.1e-15 56.7 3.3 2.1e-15 56.7 3.3 2.3 3 0 0 3 3 3 1 Hormone receptor domain Transposase_1 PF01359.18 RUS74366.1 - 2.9e-05 23.8 0.3 7.7e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_24 PF13412.6 RUS74366.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 RUS74366.1 - 0.052 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 RUS74366.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain GTSE1_N PF15259.6 RUS74366.1 - 0.11 12.7 0.5 0.75 10.0 0.3 2.5 2 1 0 2 2 2 0 G-2 and S-phase expressed 1 Kazal_2 PF07648.15 RUS74367.1 - 2.6e-07 30.6 1.8 3.9e-07 30.1 1.8 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS74367.1 - 0.031 14.3 1.6 0.054 13.5 1.6 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain EST1_DNA_bind PF10373.9 RUS74368.1 - 1.3e-37 129.9 1.9 5.8e-35 121.1 0.0 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 RUS74368.1 - 3.9e-23 82.6 11.6 3.6e-22 79.5 0.0 4.4 4 0 0 4 4 4 1 Telomerase activating protein Est1 PIN_4 PF13638.6 RUS74368.1 - 0.0001 22.6 0.9 0.002 18.4 0.0 3.0 2 0 0 2 2 2 1 PIN domain RasGAP PF00616.19 RUS74368.1 - 5.5 6.6 7.7 3.4 7.3 4.4 2.1 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Ig_3 PF13927.6 RUS74369.1 - 4.2e-37 126.6 5.3 4.4e-12 46.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS74369.1 - 5.5e-36 122.5 0.5 2.9e-11 43.3 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS74369.1 - 5.6e-28 97.1 9.2 8.4e-11 42.1 1.2 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS74369.1 - 3.8e-21 75.0 6.9 7.4e-09 35.7 0.7 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS74369.1 - 1.6e-14 54.0 9.7 2.1e-05 24.7 0.0 5.0 3 2 1 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS74369.1 - 1.6e-08 34.5 0.3 0.026 14.6 0.0 3.8 3 1 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS74369.1 - 5.6e-08 32.2 0.6 0.07 12.7 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Ig_4 PF16680.5 RUS74369.1 - 3.2e-07 30.5 1.2 0.0091 16.2 0.2 3.8 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS74369.1 - 2.7e-05 24.5 4.0 0.02 15.3 0.2 3.7 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 RUS74369.1 - 0.00022 21.0 0.9 0.17 11.7 0.0 3.7 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 RUS74369.1 - 0.0011 18.9 1.8 3 7.8 0.1 3.2 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set PF05790.15 RUS74369.1 - 0.0064 16.7 0.7 9.5 6.5 0.0 3.8 5 1 0 5 5 5 1 Immunoglobulin C2-set domain TLE_N PF03920.15 RUS74370.1 - 4.8e-72 240.2 10.6 6.8e-72 239.7 10.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 RUS74370.1 - 7e-18 64.7 15.4 0.0015 19.3 0.5 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS74370.1 - 7.6e-08 32.6 0.0 0.46 10.8 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS74370.1 - 0.011 15.1 0.0 4.2 6.6 0.0 2.7 3 1 0 3 3 3 0 WD40-like domain HALZ PF02183.18 RUS74370.1 - 0.011 15.9 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper PQQ_3 PF13570.6 RUS74370.1 - 0.094 13.2 0.3 18 6.0 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain TFIIF_alpha PF05793.12 RUS74370.1 - 0.19 10.2 22.7 0.32 9.5 22.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 RUS74370.1 - 0.21 10.9 18.9 0.33 10.3 18.9 1.2 1 0 0 1 1 1 0 BUD22 DUF2981 PF11200.8 RUS74370.1 - 0.73 9.5 4.5 4.6 6.9 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) SKA2 PF16740.5 RUS74370.1 - 1.4 8.8 6.3 0.61 9.9 3.6 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DTW PF03942.15 RUS74371.1 - 5.1e-40 137.3 0.1 6.6e-40 136.9 0.1 1.1 1 0 0 1 1 1 1 DTW domain Ribo_biogen_C PF04034.13 RUS74371.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein, C-terminal Presenilin PF01080.17 RUS74375.1 - 2.6e-07 29.8 2.6 2.7e-07 29.7 2.6 1.1 1 0 0 1 1 1 1 Presenilin Spore_coat_CotO PF14153.6 RUS74375.1 - 2.4e-05 24.3 16.1 2.9e-05 24.1 16.1 1.1 1 0 0 1 1 1 1 Spore coat protein CotO DUF4228 PF14009.6 RUS74375.1 - 4e-05 24.1 1.9 4.5e-05 23.9 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) Rtf2 PF04641.12 RUS74375.1 - 0.00021 20.8 25.7 0.00028 20.4 25.7 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger BUD22 PF09073.10 RUS74375.1 - 0.0009 18.7 33.8 0.0012 18.2 33.8 1.1 1 0 0 1 1 1 1 BUD22 Rrn6 PF10214.9 RUS74375.1 - 0.003 16.1 7.0 0.0038 15.8 7.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Smg8_Smg9 PF10220.9 RUS74375.1 - 0.0044 15.4 7.4 0.0052 15.2 7.4 1.0 1 0 0 1 1 1 1 Smg8_Smg9 SWI-SNF_Ssr4 PF08549.10 RUS74375.1 - 0.0055 15.4 4.6 0.0066 15.1 4.6 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) RPOL_N PF14700.6 RUS74375.1 - 0.0061 16.0 17.5 0.0074 15.7 17.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PA26 PF04636.13 RUS74375.1 - 0.0073 15.3 7.0 0.0089 15.0 7.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) NPR3 PF03666.13 RUS74375.1 - 0.0089 14.9 25.8 0.011 14.6 25.8 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 RUS74375.1 - 0.012 14.1 2.6 0.015 13.8 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 RUS74375.1 - 0.019 13.8 9.9 0.021 13.6 9.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BORG_CEP PF14957.6 RUS74375.1 - 0.019 16.1 10.6 0.029 15.5 10.6 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF5308 PF17233.2 RUS74375.1 - 0.022 15.0 1.8 0.034 14.4 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CAC1F_C PF16885.5 RUS74375.1 - 0.043 13.5 7.2 0.052 13.2 7.2 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF913 PF06025.12 RUS74375.1 - 0.05 12.6 9.7 0.062 12.3 9.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 RUS74375.1 - 0.058 13.2 16.6 0.074 12.8 16.6 1.1 1 0 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.14 RUS74375.1 - 0.059 13.2 34.2 0.1 12.4 34.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF3_subunit PF08597.10 RUS74375.1 - 0.066 13.1 44.7 0.095 12.6 44.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FGF-BP1 PF06473.12 RUS74375.1 - 0.079 12.8 25.8 0.11 12.3 25.8 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) FAM60A PF15396.6 RUS74375.1 - 0.085 12.9 23.7 0.11 12.4 23.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.15 RUS74375.1 - 0.095 11.6 5.6 0.15 10.9 5.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 RUS74375.1 - 0.096 12.7 18.0 0.13 12.3 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 RUS74375.1 - 0.12 11.3 16.8 0.15 11.0 16.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Otopetrin PF03189.13 RUS74375.1 - 0.13 11.1 0.7 0.14 10.9 0.7 1.2 1 0 0 1 1 1 0 Otopetrin GET2 PF08690.10 RUS74375.1 - 0.14 11.8 10.2 0.19 11.3 10.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 RUS74375.1 - 0.18 11.9 9.2 0.24 11.5 9.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CBP_BcsG PF11658.8 RUS74375.1 - 0.19 10.1 2.1 0.24 9.8 2.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF262 PF03235.14 RUS74375.1 - 0.25 11.5 8.7 0.33 11.1 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF2868 PF11067.8 RUS74375.1 - 0.27 10.7 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) SLC12 PF03522.15 RUS74375.1 - 0.33 9.9 19.8 0.43 9.6 19.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF1980 PF09323.10 RUS74375.1 - 0.34 10.8 2.3 0.54 10.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RNA_pol_3_Rpc31 PF11705.8 RUS74375.1 - 0.46 10.7 39.7 0.7 10.1 39.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spem1 PF15670.5 RUS74375.1 - 0.58 9.7 9.5 0.81 9.2 9.5 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Dsh_C PF12316.8 RUS74375.1 - 0.62 10.4 4.9 0.86 10.0 4.9 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2828 PF11443.8 RUS74375.1 - 0.62 8.1 21.9 0.8 7.7 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Vfa1 PF08432.10 RUS74375.1 - 0.73 10.1 40.1 1.2 9.4 40.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.10 RUS74375.1 - 0.87 8.9 40.3 1.1 8.5 40.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4175 PF13779.6 RUS74375.1 - 0.92 7.3 9.9 1.1 7.1 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Raftlin PF15250.6 RUS74375.1 - 1 8.0 14.5 1.3 7.7 14.5 1.1 1 0 0 1 1 1 0 Raftlin Paramyxo_ncap PF00973.19 RUS74375.1 - 1.1 8.1 15.2 1.4 7.7 15.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Membralin PF09746.9 RUS74375.1 - 1.3 8.0 9.5 1.6 7.7 9.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rgp1 PF08737.10 RUS74375.1 - 1.4 8.0 12.4 1.7 7.7 12.4 1.1 1 0 0 1 1 1 0 Rgp1 MDM1 PF15501.6 RUS74375.1 - 1.4 8.0 30.2 1.8 7.7 30.2 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF2201_N PF13203.6 RUS74375.1 - 1.4 8.4 10.8 1.9 8.1 10.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TERB2 PF15101.6 RUS74375.1 - 1.5 8.9 10.8 2.4 8.2 10.8 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 RUS74375.1 - 2.6 7.4 29.3 3.6 6.9 29.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ureide_permease PF07168.11 RUS74375.1 - 3.4 6.3 11.1 5 5.8 11.1 1.4 1 0 0 1 1 1 0 Ureide permease Acatn PF13000.7 RUS74375.1 - 3.4 6.1 8.3 11 4.4 8.3 1.7 1 1 0 1 1 1 0 Acetyl-coenzyme A transporter 1 ALMT PF11744.8 RUS74375.1 - 3.5 6.4 16.7 4.6 6.0 16.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2151 PF10221.9 RUS74375.1 - 3.6 6.1 22.2 4.4 5.8 22.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3474 PF11960.8 RUS74375.1 - 3.6 7.8 6.9 5.5 7.2 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF3807 PF12720.7 RUS74375.1 - 3.7 7.8 33.0 5.6 7.2 33.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Endostatin PF06482.11 RUS74375.1 - 4.3 6.7 10.0 5.5 6.4 10.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Trypan_PARP PF05887.11 RUS74375.1 - 4.6 7.2 11.7 6.5 6.7 11.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GREB1 PF15782.5 RUS74375.1 - 5.8 3.9 9.0 6.9 3.6 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 RUS74375.1 - 7 5.9 12.0 9.4 5.5 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gti1_Pac2 PF09729.9 RUS74375.1 - 7.4 6.6 23.6 11 6.1 23.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4551 PF15087.6 RUS74375.1 - 8.7 5.0 17.2 11 4.7 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RAB3GAP2_C PF14656.6 RUS74375.1 - 8.9 4.4 16.3 2.5e+02 -0.4 16.3 2.0 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF4775 PF16001.5 RUS74375.1 - 9.2 5.6 40.7 12 5.2 40.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Tetraspanin PF00335.20 RUS74376.1 - 3e-36 125.3 2.8 3.4e-36 125.1 2.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 RUS74376.1 - 0.024 14.7 8.4 0.39 10.8 4.3 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ig_3 PF13927.6 RUS74378.1 - 9.6e-16 58.2 0.1 4.5e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS74378.1 - 9.5e-13 48.0 0.1 4.6e-12 45.8 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 RUS74378.1 - 1.4e-10 41.2 0.1 5.2e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS74378.1 - 2.3e-09 37.4 0.2 4.4e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS74378.1 - 9.3e-06 25.8 0.2 0.00028 21.0 0.1 2.7 2 1 1 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS74378.1 - 0.0015 18.6 0.3 0.051 13.7 0.0 2.9 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 RUS74378.1 - 0.0047 17.1 0.1 0.023 14.9 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 RUS74378.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS74378.1 - 0.057 13.7 0.1 0.18 12.1 0.1 2.0 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain UL42 PF17638.2 RUS74379.1 - 0.0018 18.2 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 HCMV UL42 DUF5383 PF17355.2 RUS74379.1 - 0.0029 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5383) CrgA PF06781.12 RUS74379.1 - 0.0065 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Cell division protein CrgA TMEM132D_C PF15706.5 RUS74379.1 - 0.0074 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term zf-C2H2 PF00096.26 RUS74380.1 - 2.7e-13 49.6 18.6 0.00019 21.7 1.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS74380.1 - 7.8e-12 45.1 16.0 1.4e-05 25.3 0.2 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS74380.1 - 2.6e-08 34.0 20.4 0.0034 18.1 1.4 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS74380.1 - 3.8e-05 23.9 9.5 0.097 13.0 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS74380.1 - 5.3e-05 23.1 17.4 0.047 13.7 1.3 4.6 5 0 0 5 5 5 2 C2H2-type zinc finger C1_4 PF07975.12 RUS74380.1 - 0.00078 19.6 7.4 0.1 12.9 2.9 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 RUS74380.1 - 0.001 19.2 7.9 0.026 14.6 2.3 2.8 2 0 0 2 2 2 2 Zinc ribbon domain zf-met PF12874.7 RUS74380.1 - 0.0037 17.6 3.6 0.42 11.1 0.1 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DZR PF12773.7 RUS74380.1 - 0.068 13.2 4.6 0.22 11.6 4.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC5 PF06221.13 RUS74380.1 - 0.081 12.9 1.7 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type XPA_N PF01286.18 RUS74380.1 - 0.096 12.7 9.3 1.8 8.6 0.1 3.4 3 0 0 3 3 3 0 XPA protein N-terminal zf-AN1 PF01428.16 RUS74380.1 - 0.25 11.5 14.3 3.9 7.7 2.2 3.6 2 1 1 3 3 3 0 AN1-like Zinc finger RIG-I_C-RD PF11648.8 RUS74380.1 - 0.98 9.7 5.5 1.5 9.1 0.5 2.8 3 0 0 3 3 3 0 C-terminal domain of RIG-I zf-C2H2_8 PF15909.5 RUS74380.1 - 1.6 9.1 11.2 0.28 11.5 5.6 2.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 RUS74380.1 - 2.2 8.8 10.8 20 5.7 0.3 3.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 RUS74380.1 - 4.6 8.0 6.4 4.8 7.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Somatomedin_B PF01033.17 RUS74381.1 - 0.0006 20.1 12.1 0.0006 20.1 12.1 2.1 2 0 0 2 2 2 1 Somatomedin B domain Mito_carr PF00153.27 RUS74382.1 - 2.8e-24 84.9 0.1 1.7e-06 27.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein 7tm_1 PF00001.21 RUS74383.1 - 9.2e-13 48.1 18.5 1.7e-12 47.3 18.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS74383.1 - 1.7e-09 37.4 12.1 1.7e-09 37.4 12.1 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS74383.1 - 0.00011 22.0 20.0 0.00011 22.0 20.0 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5317 PF17248.2 RUS74383.1 - 0.039 14.0 1.4 0.039 14.0 1.4 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5317) 7tm_1 PF00001.21 RUS74385.1 - 4.8e-09 35.9 22.5 7.2e-09 35.3 22.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS74385.1 - 0.0025 17.5 21.6 0.0025 17.5 21.6 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MoCF_biosynth PF00994.24 RUS74386.1 - 2.1e-28 98.8 0.0 4.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 RUS74386.1 - 3.5e-28 98.8 0.0 3.1e-25 89.2 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FKBP_C PF00254.28 RUS74387.1 - 5.5e-48 161.2 0.6 3.3e-32 110.7 0.0 2.8 3 0 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 RUS74387.1 - 3.6e-17 61.4 12.6 1e-10 40.9 0.7 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74387.1 - 1.4e-12 46.6 8.5 1.1e-08 34.6 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS74387.1 - 1.2e-11 43.8 11.5 3.4e-09 36.2 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS74387.1 - 9.1e-09 34.9 3.6 0.00036 20.2 0.1 3.5 2 1 1 3 3 3 2 TPR repeat FKBP_N_2 PF18023.1 RUS74387.1 - 2.7e-06 27.4 0.0 0.026 14.6 0.0 3.0 2 1 0 2 2 2 2 BDBT FKBP like N-terminal TPR_6 PF13174.6 RUS74387.1 - 5.1e-06 26.8 1.9 0.00069 20.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS74387.1 - 3.8e-05 24.2 0.1 0.0094 16.7 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS74387.1 - 3.9e-05 23.8 2.1 0.00016 21.9 0.6 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS74387.1 - 0.00018 21.6 3.7 0.0013 19.0 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS74387.1 - 0.0002 21.9 0.2 0.0014 19.2 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat PknG_TPR PF16918.5 RUS74387.1 - 0.00061 18.6 0.1 0.0011 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 RUS74387.1 - 0.00086 18.6 0.1 0.023 13.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS74387.1 - 0.00097 19.6 1.0 0.0057 17.1 0.3 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS74387.1 - 0.0025 17.7 0.3 0.48 10.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Sec5 PF15469.6 RUS74387.1 - 0.0035 17.2 1.2 0.011 15.5 1.2 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 TPR_9 PF13371.6 RUS74387.1 - 0.017 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF357 PF04010.13 RUS74387.1 - 0.024 14.7 0.6 0.19 11.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) ANAPC3 PF12895.7 RUS74387.1 - 0.27 11.5 2.4 1.8 8.8 1.3 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GCIP PF13324.6 RUS74388.1 - 0.32 10.6 5.9 0.56 9.8 5.9 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2524 PF10732.9 RUS74388.1 - 0.57 10.5 8.1 7.5 6.9 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HBM PF16591.5 RUS74388.1 - 0.82 9.0 9.3 1.1 8.6 2.3 2.3 1 1 1 2 2 2 0 Helical bimodular sensor domain RecG_N PF17190.4 RUS74388.1 - 1.2 9.9 10.6 0.098 13.4 3.8 2.5 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF4661 PF15576.6 RUS74388.1 - 1.3 8.9 3.8 2.4 8.0 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) MADF_DNA_bdg PF10545.9 RUS74388.1 - 2 8.8 7.9 0.25 11.7 1.6 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF948 PF06103.11 RUS74388.1 - 2.5 8.4 4.6 24 5.3 0.2 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 RUS74388.1 - 3.6 7.1 10.8 6.6 6.2 10.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF348 PF03990.14 RUS74389.1 - 2.6e-09 36.6 6.9 0.62 9.8 0.0 7.6 8 1 1 9 9 9 2 G5-linked-Ubiquitin-like domain DUF1664 PF07889.12 RUS74389.1 - 2e-08 34.3 7.0 0.026 14.6 0.6 3.9 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) Laminin_II PF06009.12 RUS74389.1 - 1e-06 28.8 3.6 0.48 10.4 0.1 3.6 1 1 3 4 4 4 3 Laminin Domain II DUF948 PF06103.11 RUS74389.1 - 1.3e-06 28.6 6.0 0.11 12.8 1.0 4.1 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) EspB_PE PF18625.1 RUS74389.1 - 5.1e-06 26.8 0.0 2.5 8.6 0.0 4.9 4 1 1 6 6 6 1 ESX-1 secreted protein B PE domain EzrA PF06160.12 RUS74389.1 - 0.00019 19.7 0.2 0.019 13.2 0.0 1.9 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA PI_PP_I PF18363.1 RUS74389.1 - 0.00026 21.1 0.0 2.6 8.3 0.0 3.6 1 1 1 3 3 3 1 Phosphoinositide phosphatase insertion domain YabA PF06156.13 RUS74389.1 - 0.00069 20.2 0.2 1.5 9.5 0.0 3.5 1 1 2 3 3 3 1 Initiation control protein YabA MCPsignal PF00015.21 RUS74389.1 - 0.00069 19.5 13.7 0.042 13.6 3.8 3.3 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 RUS74389.1 - 0.0012 18.6 13.4 0.086 12.5 2.0 3.0 1 1 2 3 3 3 2 Syntaxin CDH1_2_SANT_HL1 PF18375.1 RUS74389.1 - 0.0013 19.3 0.3 1.3 9.7 0.1 3.1 1 1 2 3 3 3 1 CDH1/2 SANT-Helical linker 1 FlaC_arch PF05377.11 RUS74389.1 - 0.0015 18.9 4.3 6.8 7.2 0.4 5.6 1 1 5 6 6 6 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 RUS74389.1 - 0.0019 18.3 0.4 0.18 11.9 0.1 3.0 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Bep_C_terminal PF17841.1 RUS74389.1 - 0.002 18.3 1.0 28 5.0 0.0 3.7 1 1 1 3 3 3 0 BID domain of Bartonella effector protein (Bep) Baculo_PEP_C PF04513.12 RUS74389.1 - 0.0026 17.8 0.1 0.18 11.8 0.0 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 RUS74389.1 - 0.0027 17.7 0.0 0.54 10.3 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 RUS74389.1 - 0.0029 17.4 0.0 0.16 11.7 0.0 2.5 1 1 3 4 4 4 2 Protein of unknown function (DUF745) Fib_alpha PF08702.10 RUS74389.1 - 0.003 17.7 7.1 0.48 10.6 0.8 3.4 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family Serine_rich PF08824.10 RUS74389.1 - 0.0055 16.7 1.1 0.18 11.8 0.3 2.8 1 1 2 3 3 3 1 Serine rich protein interaction domain BLOC1_2 PF10046.9 RUS74389.1 - 0.0068 16.7 0.1 14 6.1 0.0 3.8 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 RUS74389.1 - 0.0088 15.5 2.1 0.75 9.2 0.4 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4618) DASH_Dad2 PF08654.10 RUS74389.1 - 0.0094 16.4 1.5 28 5.2 0.1 3.9 1 1 2 3 3 3 0 DASH complex subunit Dad2 DUF2951 PF11166.8 RUS74389.1 - 0.0096 16.1 5.0 6.8 7.0 1.2 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2951) V_ATPase_I PF01496.19 RUS74389.1 - 0.0096 13.9 6.2 0.023 12.6 6.2 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 RUS74389.1 - 0.017 14.8 0.3 0.68 9.5 0.2 2.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3718 PF12514.8 RUS74389.1 - 0.025 14.8 4.8 14 5.9 0.1 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3718) DUF5334 PF17268.2 RUS74389.1 - 0.025 14.9 17.0 34 4.8 0.2 7.2 1 1 9 10 10 10 0 Family of unknown function (DUF5334) DUF3450 PF11932.8 RUS74389.1 - 0.025 13.9 0.2 1.5 8.0 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) RmuC PF02646.16 RUS74389.1 - 0.052 12.7 5.5 3.6 6.7 0.2 3.0 1 1 1 3 3 3 0 RmuC family Laminin_I PF06008.14 RUS74389.1 - 0.055 13.2 1.9 1.8 8.2 0.2 2.1 1 1 1 2 2 2 0 Laminin Domain I LXG PF04740.12 RUS74389.1 - 0.056 13.1 3.2 0.89 9.2 0.7 2.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.19 RUS74389.1 - 0.068 11.0 0.6 0.096 10.5 0.6 1.2 1 0 0 1 1 1 0 Myosin tail LIF_OSM PF01291.17 RUS74389.1 - 0.076 13.2 1.3 2.9 8.0 0.2 2.6 1 1 2 3 3 3 0 LIF / OSM family Occludin_ELL PF07303.13 RUS74389.1 - 0.077 13.7 0.8 10 6.9 0.1 3.2 1 1 2 3 3 3 0 Occludin homology domain DUF2239 PF09998.9 RUS74389.1 - 0.11 12.2 1.6 6.7 6.5 0.1 2.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Sec34 PF04136.15 RUS74389.1 - 0.13 12.1 0.1 13 5.7 0.0 2.6 1 1 2 3 3 3 0 Sec34-like family TMPIT PF07851.13 RUS74389.1 - 0.14 11.4 2.8 1.3 8.2 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF3087 PF11286.8 RUS74389.1 - 0.18 11.3 0.8 3.1 7.2 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3087) DegS PF05384.11 RUS74389.1 - 0.2 11.2 3.6 1.2 8.6 0.8 2.6 1 1 3 4 4 4 0 Sensor protein DegS NADH_dhqG_C PF09326.11 RUS74389.1 - 0.25 12.0 21.6 26 5.6 0.0 8.7 10 0 0 10 10 9 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal DUF327 PF03885.13 RUS74389.1 - 0.3 11.1 2.9 5.5 6.9 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF327) DUF724 PF05266.14 RUS74389.1 - 0.31 10.8 2.8 3.2 7.5 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) COG6 PF06419.11 RUS74389.1 - 0.32 9.2 3.0 8.5 4.5 0.1 2.6 1 1 2 3 3 3 0 Conserved oligomeric complex COG6 DUF2576 PF10845.8 RUS74389.1 - 0.59 9.8 20.0 4.4 7.0 0.1 7.5 1 1 5 7 7 7 0 Protein of unknown function (DUF2576) ParD_like PF11903.8 RUS74389.1 - 8.1 6.6 22.3 36 4.5 0.1 8.1 2 2 9 12 12 11 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system Trs65 PF12735.7 RUS74390.1 - 0.00031 20.3 0.0 5.4 6.3 0.0 4.7 1 1 1 2 2 2 2 TRAPP trafficking subunit Trs65 Corona_I PF03187.14 RUS74390.1 - 0.0019 17.9 1.8 1.7 8.2 0.1 2.9 1 1 2 3 3 3 2 Corona nucleocapsid I protein MAM PF00629.23 RUS74390.1 - 0.036 14.0 0.9 6.7 6.6 0.1 3.3 1 1 1 2 2 2 0 MAM domain, meprin/A5/mu Phage_holin_1 PF04531.13 RUS74390.1 - 0.057 14.0 0.0 0.25 11.9 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage holin ANATO PF01821.18 RUS74390.1 - 0.066 14.1 13.7 42 5.1 0.1 6.0 2 2 4 6 6 6 0 Anaphylotoxin-like domain Resolvase PF00239.21 RUS74391.1 - 0.0029 17.7 0.2 0.14 12.3 0.0 2.5 1 1 0 2 2 2 1 Resolvase, N terminal domain Baculo_PEP_C PF04513.12 RUS74391.1 - 0.01 15.9 3.2 2.3 8.3 0.3 3.3 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus TelA PF05816.11 RUS74391.1 - 0.45 9.5 6.3 3.5 6.6 3.8 2.3 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF4407 PF14362.6 RUS74391.1 - 0.9 8.8 5.5 0.66 9.3 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 RUS74391.1 - 1.3 9.1 9.0 0.77 9.8 5.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 RUS74391.1 - 1.8 8.6 8.4 2.2 8.3 1.2 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 RUS74391.1 - 3.1 8.2 9.7 2.8 8.4 2.3 3.3 2 1 1 3 3 3 0 Syntaxin-like protein COG2 PF06148.11 RUS74391.1 - 4 7.5 5.5 1.4 9.1 0.2 2.8 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.19 RUS74391.1 - 5.3 6.7 8.5 1.7 8.2 5.1 2.0 2 0 0 2 2 2 0 GrpE DUF1664 PF07889.12 RUS74391.1 - 6.4 6.8 8.6 4.3 7.4 1.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 RUS74391.1 - 8.7 6.4 18.5 19 5.4 0.1 4.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NuA4 PF09340.10 RUS74393.1 - 0.71 9.8 6.7 0.9 9.5 0.0 3.4 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 YlqD PF11068.8 RUS74394.1 - 0.26 11.7 10.0 0.39 11.1 9.2 1.7 1 1 0 1 1 1 0 YlqD protein Pinin_SDK_memA PF04696.13 RUS74394.1 - 0.87 9.6 9.3 2 8.5 9.3 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region F5_F8_type_C PF00754.25 RUS74395.1 - 7.8e-42 142.4 7.8 9.4e-25 87.2 0.2 3.2 3 0 0 3 3 3 3 F5/8 type C domain Rsm1 PF08600.10 RUS74395.1 - 0.0052 16.9 0.7 0.013 15.7 0.4 1.9 2 0 0 2 2 2 1 Rsm1-like MIF4G PF02854.19 RUS74395.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain C2 PF00168.30 RUS74398.1 - 9.6e-34 115.8 0.2 4.1e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain DUF2626 PF11117.8 RUS74399.1 - 8.8 7.1 22.6 2.7 8.8 4.1 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2626) zf-Di19 PF05605.12 RUS74400.1 - 0.12 12.7 4.6 1.7 9.0 0.1 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RUS74400.1 - 0.45 11.5 6.5 3.2 8.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.14 RUS74400.1 - 0.74 9.8 6.7 1.8 8.6 1.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Herpes_UL32 PF06070.11 RUS74400.1 - 0.77 7.4 4.1 1 7.0 4.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 zf-C2H2 PF00096.26 RUS74400.1 - 4.2 8.0 6.5 11 6.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rho_GDI PF02115.17 RUS74401.1 - 7.6e-63 211.8 5.2 8.8e-63 211.6 5.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TBCA PF02970.16 RUS74401.1 - 1.1 9.7 5.6 13 6.2 5.6 2.5 1 1 0 1 1 1 0 Tubulin binding cofactor A PALP PF00291.25 RUS74402.1 - 1.3e-65 221.7 0.3 1.6e-65 221.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NPL4 PF05021.15 RUS74404.1 - 2.1e-117 391.9 0.0 2.9e-117 391.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 RUS74404.1 - 2.4e-58 196.4 0.1 4.3e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 RUS74404.1 - 1.4e-21 76.8 0.0 3.4e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 RUS74404.1 - 0.0032 16.7 2.1 0.0032 16.7 2.1 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others ADD_DNMT3 PF17980.1 RUS74404.1 - 0.022 14.8 0.6 0.052 13.5 0.6 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 G10 PF01125.17 RUS74405.1 - 2.2e-67 225.4 4.8 2.4e-67 225.2 4.8 1.0 1 0 0 1 1 1 1 G10 protein Vitellogenin_N PF01347.22 RUS74406.1 - 7.7e-10 37.8 0.0 7.8e-10 37.8 0.0 1.0 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 RUS74407.1 - 2.2e-13 50.1 0.6 4.5e-13 49.1 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.25 RUS74408.1 - 1.6e-06 28.5 0.0 7.5e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 RUS74408.1 - 8.7e-05 22.9 0.2 0.00018 21.9 0.2 1.5 1 0 0 1 1 1 1 C8 domain Acyltransferase PF01553.21 RUS74409.1 - 2e-17 63.1 0.0 3.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RUS74409.1 - 6.5e-15 55.0 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus TatD_DNase PF01026.21 RUS74410.1 - 2.6e-56 190.9 0.0 3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RUS74410.1 - 0.0035 17.2 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase TPR_12 PF13424.6 RUS74411.1 - 5e-08 33.1 8.3 0.0018 18.5 1.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74411.1 - 3e-05 23.6 2.1 1.7 8.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS74411.1 - 0.0018 18.1 4.5 2 8.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74411.1 - 0.004 17.2 6.1 3.9 7.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS74411.1 - 0.14 12.7 7.5 11 6.6 1.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS74411.1 - 0.28 11.9 3.1 16 6.4 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS74411.1 - 0.43 10.9 1.8 5.2 7.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TIR_2 PF13676.6 RUS74413.1 - 0.00028 21.5 0.3 0.0011 19.6 0.0 2.1 2 0 0 2 2 2 1 TIR domain CDC45 PF02724.14 RUS74413.1 - 0.013 13.8 4.8 0.024 13.0 4.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 RUS74413.1 - 0.19 10.5 8.2 0.56 8.9 8.2 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM51 PF15345.6 RUS74413.1 - 0.49 10.2 11.5 2.3 8.0 11.5 2.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4820 PF16091.5 RUS74413.1 - 0.72 9.2 8.5 2.3 7.5 8.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PIEZO PF15917.5 RUS74413.1 - 0.99 8.8 19.3 1.5 8.3 10.8 2.4 2 0 0 2 2 2 0 Piezo CobT PF06213.12 RUS74413.1 - 1 8.7 18.2 2.9 7.2 18.2 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1682 PF07946.14 RUS74413.1 - 1.3 8.2 7.7 2.2 7.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 RUS74413.1 - 2 7.9 16.9 3.6 7.1 16.9 1.3 1 0 0 1 1 1 0 DDRGK domain EIIBC-GUT_N PF03612.14 RUS74413.1 - 2.1 8.1 10.4 8 6.2 10.4 2.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3408 PF11888.8 RUS74413.1 - 4.1 7.5 16.1 3.4 7.8 12.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF5523 PF17661.1 RUS74413.1 - 6 6.5 17.0 0.32 10.6 10.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SpoIIP PF07454.11 RUS74413.1 - 8.1 5.8 23.2 0.033 13.6 7.2 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 RUS74413.1 - 8.7 6.0 11.9 20 4.8 11.9 1.5 1 0 0 1 1 1 0 Connexin CBM_14 PF01607.24 RUS74418.1 - 8e-23 80.4 15.4 3.9e-11 42.9 3.8 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Opy2 PF09463.10 RUS74418.1 - 1.1 9.7 2.7 40 4.6 0.2 2.5 2 0 0 2 2 2 0 Opy2 protein PNP_UDP_1 PF01048.20 RUS74421.1 - 0.0045 16.3 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily UAA PF08449.11 RUS74422.1 - 3e-59 200.7 15.8 3.8e-59 200.4 15.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 RUS74422.1 - 1.6e-13 50.7 7.9 7.1e-08 32.1 1.3 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 RUS74422.1 - 5.2e-10 39.6 25.9 5.9e-05 23.3 2.1 2.9 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 RUS74422.1 - 8.1e-05 21.7 1.4 8.1e-05 21.7 1.4 2.2 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 RUS74422.1 - 0.00084 18.9 7.8 0.00084 18.9 7.8 1.6 1 1 1 2 2 2 1 Solute carrier family 35 TMEM234 PF10639.9 RUS74422.1 - 0.26 11.4 4.6 0.82 9.7 0.7 2.7 2 1 0 2 2 2 0 Putative transmembrane family 234 Pox_A14 PF05767.12 RUS74422.1 - 0.84 9.8 8.4 1.7 8.8 1.5 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2569 PF10754.9 RUS74422.1 - 3.5 8.1 19.7 0.24 11.9 2.6 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2569) Transposase_1 PF01359.18 RUS74423.1 - 6e-20 70.9 0.1 1.5e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) Lectin_C PF00059.21 RUS74423.1 - 2.3e-11 44.4 0.7 5.3e-11 43.2 0.3 1.8 2 0 0 2 2 2 1 Lectin C-type domain DDE_3 PF13358.6 RUS74423.1 - 0.0012 18.7 0.0 0.0018 18.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Chordopox_A33R PF05966.12 RUS74423.1 - 0.019 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Pkinase PF00069.25 RUS74425.1 - 1.8e-15 57.0 0.1 2.3e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74425.1 - 8.4e-13 48.2 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Rep_4 PF05797.11 RUS74425.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) MAGE PF01454.19 RUS74426.1 - 0.057 13.1 0.1 0.062 13.0 0.1 1.1 1 0 0 1 1 1 0 MAGE family DUF3868 PF12984.7 RUS74426.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) FtsA PF14450.6 RUS74426.1 - 0.11 13.0 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsA HrcA PF01628.21 RUS74426.1 - 0.14 12.0 0.8 0.16 11.9 0.8 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain TetR_C_5 PF08360.11 RUS74427.1 - 0.0066 16.6 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 QacR-like protein, C-terminal region YkyA PF10368.9 RUS74427.1 - 0.69 9.6 5.5 0.13 11.9 1.8 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Bombesin PF02044.17 RUS74429.1 - 0.14 12.3 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 Bombesin-like peptide Claudin_3 PF06653.11 RUS74429.1 - 0.17 11.8 4.1 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF3046 PF11248.8 RUS74430.1 - 5e-07 30.0 0.0 20 5.6 0.0 5.7 1 1 8 9 9 9 3 Protein of unknown function (DUF3046) Sorb PF02208.16 RUS74430.1 - 1.5e-05 24.8 23.0 36 4.3 0.1 10.6 1 1 11 12 12 12 0 Sorbin homologous domain TPM_phosphatase PF04536.14 RUS74430.1 - 2.7e-05 24.3 0.0 4.7 7.4 0.0 3.7 1 1 2 4 4 4 2 TPM domain Glyco_hydro_45 PF02015.16 RUS74430.1 - 0.0011 18.9 0.0 72 3.2 0.0 4.8 1 1 2 6 6 6 0 Glycosyl hydrolase family 45 PCB_OB PF17092.5 RUS74430.1 - 0.058 14.2 0.4 14 6.5 0.1 3.0 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain SMC_N PF02463.19 RUS74430.1 - 0.35 10.3 3.4 34 3.8 0.0 4.6 1 1 3 5 5 5 0 RecF/RecN/SMC N terminal domain DUF3368 PF11848.8 RUS74431.1 - 3.7e-10 39.4 0.5 7.6 6.4 0.0 8.8 8 1 1 9 9 9 1 Domain of unknown function (DUF3368) Big_3 PF07523.12 RUS74431.1 - 1.3e-05 25.4 3.0 3.2e+02 1.7 0.0 8.8 10 0 0 10 10 10 0 Bacterial Ig-like domain (group 3) DUF4296 PF14129.6 RUS74431.1 - 0.0019 18.8 10.6 62 4.3 0.4 7.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4296) Plant_tran PF04827.14 RUS74431.1 - 0.086 12.4 20.8 4.2 6.9 0.5 4.7 1 1 5 6 6 6 0 Plant transposon protein Nucleoporin_FG PF13634.6 RUS74432.1 - 7.7e-09 36.3 0.0 0.00056 20.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin FG repeat region Ribosomal_L37ae PF01780.19 RUS74432.1 - 0.00036 20.6 16.3 1.8 8.7 0.8 4.5 1 1 5 6 6 6 6 Ribosomal L37ae protein family Evr1_Alr PF04777.13 RUS74432.1 - 0.0038 17.7 11.8 7.1 7.2 2.1 4.1 1 1 1 2 2 2 1 Erv1 / Alr family Phage-A118_gp45 PF10653.9 RUS74432.1 - 0.13 12.3 0.5 40 4.3 0.0 3.7 1 1 5 6 6 6 0 Protein gp45 of Bacteriophage A118 Cys_knot PF00007.22 RUS74432.1 - 0.25 11.6 4.6 37 4.7 0.2 2.8 1 1 0 2 2 2 0 Cystine-knot domain CxC6 PF18721.1 RUS74432.1 - 2.6 8.4 8.1 5.8e+02 0.9 8.1 3.1 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases DUF1691 PF07950.11 RUS74432.1 - 6.7 7.5 7.1 3e+02 2.2 7.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) ubiquitin PF00240.23 RUS74433.1 - 1.7e-06 27.6 0.3 4.8e-06 26.2 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 RUS74433.1 - 0.046 14.2 0.1 0.075 13.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Mre11_DNA_bind PF04152.14 RUS74434.1 - 1.4e-45 155.6 0.3 1.4e-45 155.6 0.3 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RUS74434.1 - 2.4e-05 24.9 0.7 5.1e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1727 PF08353.10 RUS74434.1 - 0.077 12.9 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) DUF4586 PF15239.6 RUS74435.1 - 8.1e-100 334.9 10.7 9.5e-100 334.7 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Uso1_p115_head PF04869.14 RUS74436.1 - 7.8e-67 225.6 0.6 2.1e-66 224.2 0.6 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 RUS74436.1 - 1.5e-31 108.1 3.4 1.5e-31 108.1 3.4 2.4 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor V-ATPase_H_N PF03224.14 RUS74436.1 - 0.0085 15.4 6.5 0.46 9.7 1.2 3.7 1 1 2 3 3 3 2 V-ATPase subunit H GOLGA2L5 PF15070.6 RUS74436.1 - 0.027 13.1 4.9 0.043 12.5 4.9 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Ribosomal_L29 PF00831.23 RUS74436.1 - 0.062 13.3 1.1 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Ribosomal L29 protein Rx_N PF18052.1 RUS74436.1 - 0.071 13.4 0.4 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Rx N-terminal domain PRKG1_interact PF15898.5 RUS74436.1 - 0.28 12.1 11.9 3.1 8.8 3.8 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4401 PF14351.6 RUS74436.1 - 0.43 9.9 1.6 0.66 9.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) SlyX PF04102.12 RUS74436.1 - 1.5 9.5 7.8 11 6.7 3.5 3.2 2 0 0 2 2 2 0 SlyX PspA_IM30 PF04012.12 RUS74436.1 - 6.3 6.3 10.7 2.1 7.9 7.5 1.8 2 0 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 RUS74436.1 - 7.9 5.3 9.7 21 3.9 7.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein ELO PF01151.18 RUS74437.1 - 1.8e-43 148.9 26.4 2.9e-43 148.2 26.4 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family SH2 PF00017.24 RUS74438.1 - 8.2e-14 51.5 1.2 1.4e-13 50.8 0.1 2.1 2 0 0 2 2 2 1 SH2 domain MHC_I PF00129.18 RUS74438.1 - 0.0022 17.6 0.4 0.0022 17.6 0.4 2.3 3 1 0 3 3 3 1 Class I Histocompatibility antigen, domains alpha 1 and 2 7tm_2 PF00002.24 RUS74439.1 - 3.5e-11 42.9 16.2 5.3e-11 42.3 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3488 PF11992.8 RUS74439.1 - 0.022 13.7 0.1 0.022 13.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) Ribosomal_L34 PF00468.17 RUS74439.1 - 0.041 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L34 DUF2834 PF11196.8 RUS74439.1 - 0.071 13.5 2.1 0.2 12.1 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) zf-CHCC PF10276.9 RUS74440.1 - 6.8e-10 38.8 0.2 1.1e-09 38.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain Evr1_Alr PF04777.13 RUS74441.1 - 8.8e-28 96.7 2.8 8.8e-28 96.7 2.8 1.9 2 0 0 2 2 2 1 Erv1 / Alr family FAD_SOX PF18371.1 RUS74441.1 - 0.039 14.3 0.0 0.17 12.2 0.0 2.0 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Ank_2 PF12796.7 RUS74442.1 - 2.8e-93 306.6 55.7 8.6e-14 51.9 0.4 11.8 2 2 14 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74442.1 - 2.4e-48 161.9 20.7 4.8e-06 27.0 0.0 12.7 9 3 6 15 15 15 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS74442.1 - 4.7e-44 147.9 15.5 5.8e-07 29.7 0.3 13.7 9 3 3 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS74442.1 - 3.9e-43 140.5 19.5 0.0075 16.7 0.0 18.6 20 0 0 20 20 20 12 Ankyrin repeat Ank PF00023.30 RUS74442.1 - 4.4e-33 112.3 34.2 0.0013 19.0 0.1 17.9 18 1 1 19 19 19 10 Ankyrin repeat SOCS_box PF07525.16 RUS74442.1 - 0.022 15.1 0.1 0.091 13.1 0.0 2.1 2 0 0 2 2 2 0 SOCS box 7tm_1 PF00001.21 RUS74443.1 - 3.9e-11 42.8 19.2 5.4e-11 42.3 19.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS74443.1 - 4.6e-11 42.6 19.4 7.6e-11 41.9 19.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS74443.1 - 0.0026 17.5 15.7 0.0026 17.5 15.7 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3592 PF12158.8 RUS74443.1 - 0.37 10.8 1.6 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Ras PF00071.22 RUS74444.1 - 2.9e-24 85.5 0.0 5.1e-16 58.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RUS74444.1 - 1.7e-06 28.3 0.0 0.0074 16.5 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS74444.1 - 0.0004 19.9 0.0 0.61 9.5 0.0 2.4 1 1 0 2 2 2 2 ADP-ribosylation factor family Mito_fiss_Elm1 PF06258.11 RUS74444.1 - 0.094 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 cEGF PF12662.7 RUS74445.1 - 2.1e-07 30.7 26.3 3e-06 27.0 1.6 5.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS74445.1 - 1.2e-06 28.7 12.1 1.2e-06 28.7 12.1 5.2 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 RUS74445.1 - 0.0001 22.6 7.4 0.0001 22.6 7.4 4.5 5 0 0 5 5 5 2 Pvs28 EGF domain EGF_3 PF12947.7 RUS74445.1 - 0.0027 17.9 7.5 0.0027 17.9 7.5 6.2 6 1 1 7 7 7 2 EGF domain EGF PF00008.27 RUS74445.1 - 0.0057 16.9 8.3 0.0057 16.9 8.3 4.9 5 0 0 5 5 5 2 EGF-like domain EGF_CA PF07645.15 RUS74446.1 - 3.4e-05 23.9 14.9 3.4e-05 23.9 14.9 3.6 3 1 1 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 RUS74446.1 - 0.0041 17.0 10.7 0.0055 16.6 0.5 3.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EphA2_TM PF14575.6 RUS74446.1 - 0.013 16.4 0.0 0.027 15.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF PF00008.27 RUS74446.1 - 0.049 13.9 25.4 1.6 9.1 0.6 4.4 4 1 0 4 4 4 0 EGF-like domain EGF_3 PF12947.7 RUS74446.1 - 0.49 10.6 24.3 0.14 12.4 7.6 3.9 3 1 0 3 3 3 0 EGF domain NAD_Gly3P_dh_N PF01210.23 RUS74448.1 - 9.5e-52 175.1 0.9 1.7e-51 174.3 0.3 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 RUS74448.1 - 8.5e-49 165.5 0.3 2.2e-48 164.1 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 RUS74448.1 - 0.0012 19.4 2.3 0.38 11.4 0.0 3.1 4 0 0 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 RUS74448.1 - 0.011 15.3 0.1 0.26 10.8 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 RUS74448.1 - 0.12 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase HIG_1_N PF04588.13 RUS74449.1 - 1.3e-15 57.4 1.5 1.7e-15 57.0 1.5 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Glypican PF01153.19 RUS74450.1 - 0.77 8.5 6.1 0.098 11.5 0.7 2.1 2 0 0 2 2 2 0 Glypican 7TM_GPCR_Srx PF10328.9 RUS74451.1 - 6.6e-08 32.5 9.2 8.5e-08 32.1 9.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS74451.1 - 0.00011 21.6 6.4 0.00016 21.1 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.9 RUS74451.1 - 5.1 6.0 13.1 9.8 5.0 13.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_1 PF00001.21 RUS74452.1 - 1.7e-12 47.2 19.5 2.4e-12 46.8 19.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS74452.1 - 5.9e-10 38.9 8.5 5.9e-10 38.9 8.5 2.5 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS74452.1 - 1.3e-05 24.8 21.3 2.9e-05 23.6 21.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS74452.1 - 0.00026 20.7 24.3 0.00026 20.7 24.3 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 2TM PF13239.6 RUS74452.1 - 1 9.7 0.0 1 9.7 0.0 3.1 3 1 0 3 3 3 0 2TM domain EF-hand_7 PF13499.6 RUS74453.1 - 2.8e-16 59.7 0.8 7.6e-09 35.9 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS74453.1 - 7.7e-15 53.3 2.8 6.8e-07 28.4 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS74453.1 - 2.8e-14 51.7 1.9 1.3e-06 27.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS74453.1 - 1.2e-09 37.9 3.2 0.00074 19.3 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS74453.1 - 3.2e-08 32.7 1.8 0.00015 21.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RUS74453.1 - 1.3e-07 31.8 0.0 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 RUS74453.1 - 1.9e-05 25.4 0.1 9.5e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 RUS74453.1 - 0.03 14.7 0.1 1.1 9.6 0.0 2.6 1 1 2 3 3 3 0 EF-hand domain GGACT PF06094.12 RUS74454.1 - 5.9e-23 81.8 0.0 8.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 RUS74454.1 - 0.00016 22.0 0.0 0.00085 19.7 0.0 2.0 1 1 0 1 1 1 1 AIG2-like family RVT_1 PF00078.27 RUS74455.1 - 7.4e-25 87.8 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMS1_N PF10433.9 RUS74456.1 - 5.5e-89 299.0 0.0 6.6e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term TMEM154 PF15102.6 RUS74457.1 - 0.01 15.7 0.2 0.01 15.7 0.2 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF179 PF02622.15 RUS74458.1 - 0.19 11.7 0.0 7.4 6.5 0.0 3.1 1 1 1 2 2 2 0 Uncharacterized ACR, COG1678 HRM PF02793.22 RUS74459.1 - 0.1 12.9 0.1 8.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Hormone receptor domain IL4Ra_N PF09238.10 RUS74460.1 - 1.7 9.1 6.6 53 4.2 0.4 3.1 1 1 2 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal ERG2_Sigma1R PF04622.12 RUS74460.1 - 1.9 7.8 6.9 12 5.2 1.3 3.6 1 1 3 4 4 4 0 ERG2 and Sigma1 receptor like protein Abhydrolase_5 PF12695.7 RUS74462.1 - 3.9e-08 33.2 0.0 3.2e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS74462.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS74462.1 - 0.0032 18.1 1.5 0.012 16.2 1.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family SelP_N PF04592.14 RUS74463.1 - 0.079 12.4 12.4 0.11 11.9 12.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 RUS74463.1 - 0.28 9.7 1.0 0.32 9.5 1.0 1.0 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 RUS74463.1 - 0.9 10.2 4.8 1.3 9.7 4.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Telomere_Sde2_2 PF13297.6 RUS74466.1 - 1.2e-24 85.7 0.3 3.4e-24 84.3 0.3 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 RUS74466.1 - 1.2e-23 83.7 0.8 1.2e-23 83.7 0.8 1.8 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF3435 PF11917.8 RUS74466.1 - 2.3 7.0 7.8 3.6 6.4 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) AAA PF00004.29 RUS74467.1 - 9.9e-86 284.9 0.0 8.5e-47 158.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS74467.1 - 3.6e-15 55.5 0.8 5.6e-09 35.7 0.3 3.0 2 0 0 2 2 2 2 AAA+ lid domain Nucleolin_bd PF16725.5 RUS74467.1 - 7.4e-15 54.4 0.1 1.9e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 Nucleolin binding domain AAA_16 PF13191.6 RUS74467.1 - 3.3e-11 43.8 3.4 0.00014 22.3 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 RUS74467.1 - 1.2e-10 41.7 1.0 1.3e-05 25.4 0.0 3.7 4 1 0 4 4 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RUS74467.1 - 1.5e-10 41.2 0.1 0.0001 22.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS74467.1 - 2.4e-09 37.2 0.0 0.00015 21.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS74467.1 - 9.1e-09 35.7 2.8 0.016 15.5 0.0 4.7 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.22 RUS74467.1 - 1.4e-07 31.9 0.1 0.056 13.8 0.0 3.6 3 1 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 RUS74467.1 - 4.5e-07 30.1 0.0 0.0027 17.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RUS74467.1 - 5.6e-07 29.4 0.0 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 RUS74467.1 - 1.5e-06 27.6 0.1 0.0015 17.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain ABC_tran PF00005.27 RUS74467.1 - 1.9e-06 28.5 0.5 0.047 14.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_14 PF13173.6 RUS74467.1 - 4.1e-06 26.8 0.0 0.0018 18.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS74467.1 - 7.4e-06 26.0 0.9 2 8.3 0.0 3.7 4 0 0 4 4 3 2 NACHT domain AAA_18 PF13238.6 RUS74467.1 - 1.2e-05 25.8 0.3 0.0042 17.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 RUS74467.1 - 2.1e-05 25.0 0.2 0.061 13.7 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 RUS74467.1 - 2.4e-05 24.7 0.4 0.067 13.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 RUS74467.1 - 3.9e-05 23.7 0.8 4.5 7.1 0.0 4.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 RUS74467.1 - 4.1e-05 23.6 0.0 0.0048 16.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 RUS74467.1 - 4.8e-05 22.8 0.5 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RUS74467.1 - 7.4e-05 22.1 0.7 0.084 12.1 0.1 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 RUS74467.1 - 8.8e-05 22.1 0.4 0.31 10.5 0.0 3.1 3 0 0 3 3 2 2 P-loop containing dynein motor region DUF815 PF05673.13 RUS74467.1 - 0.00016 20.9 0.0 0.078 12.1 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 RUS74467.1 - 0.00017 21.4 0.1 1.1 8.9 0.0 3.5 4 0 0 4 4 3 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 RUS74467.1 - 0.00028 21.0 0.0 0.085 13.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 RUS74467.1 - 0.00031 20.8 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 RUS74467.1 - 0.00055 19.9 0.2 1.6 8.5 0.2 3.9 3 1 0 3 3 3 1 Bacterial dnaA protein ResIII PF04851.15 RUS74467.1 - 0.0017 18.4 0.2 0.48 10.4 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 RUS74467.1 - 0.0021 17.8 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Vps4_C PF09336.10 RUS74467.1 - 0.0023 17.9 0.3 0.026 14.5 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 RUS74467.1 - 0.0024 17.6 0.0 0.069 12.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RUS74467.1 - 0.0031 16.7 1.8 2.7 7.1 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain PhoH PF02562.16 RUS74467.1 - 0.0034 16.8 0.2 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein RsgA_GTPase PF03193.16 RUS74467.1 - 0.0071 16.3 0.0 1.4 8.8 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 RUS74467.1 - 0.0087 15.7 3.8 4.2 6.9 0.0 3.8 3 1 1 4 4 4 0 AAA domain SKI PF01202.22 RUS74467.1 - 0.013 15.6 0.1 0.69 10.0 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase AAA_24 PF13479.6 RUS74467.1 - 0.025 14.3 0.0 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 RUS74467.1 - 0.031 14.4 0.1 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase-like family AAA_3 PF07726.11 RUS74467.1 - 0.035 14.0 0.0 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 RUS74467.1 - 0.039 13.4 0.0 8.2 5.8 0.0 3.3 3 1 1 4 4 4 0 Bacterial TniB protein T2SSE PF00437.20 RUS74467.1 - 0.04 13.0 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 RUS74467.1 - 0.043 13.6 1.8 0.48 10.1 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase IPT PF01745.16 RUS74467.1 - 0.061 12.7 0.4 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Isopentenyl transferase AAA_23 PF13476.6 RUS74467.1 - 0.065 13.7 0.3 0.065 13.7 0.3 4.4 4 2 1 5 5 3 0 AAA domain AAA_29 PF13555.6 RUS74467.1 - 0.19 11.5 0.2 21 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 RUS74467.1 - 0.66 9.7 14.8 1.6 8.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 RUS74467.1 - 2.1 7.6 5.9 10 5.4 0.0 3.5 3 1 0 3 3 3 0 KaiC CDC45 PF02724.14 RUS74467.1 - 3.3 5.9 11.2 6.5 4.9 11.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Amidase PF01425.21 RUS74468.1 - 5.1e-74 249.9 0.0 2e-52 178.7 0.0 3.1 1 1 2 3 3 3 3 Amidase TP_methylase PF00590.20 RUS74469.1 - 2.5e-23 83.1 0.2 7.4e-23 81.6 0.2 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ZNRF_3_ecto PF18212.1 RUS74469.1 - 0.034 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 ZNRF-3 Ectodomain NAD_kinase PF01513.21 RUS74470.1 - 4.1e-07 29.5 0.0 2.5e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 RUS74470.1 - 0.015 15.0 0.0 0.056 13.1 0.0 2.0 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain Cation_efflux PF01545.21 RUS74471.1 - 3.3e-44 151.0 13.5 3.7e-44 150.8 13.5 1.0 1 0 0 1 1 1 1 Cation efflux family GRP PF07172.11 RUS74471.1 - 0.00027 21.6 1.9 0.0006 20.5 1.9 1.5 1 0 0 1 1 1 1 Glycine rich protein family Sensor PF13796.6 RUS74471.1 - 0.00094 19.3 0.3 0.00094 19.3 0.3 2.3 3 0 0 3 3 3 1 Putative sensor MgtE PF01769.16 RUS74471.1 - 0.91 9.9 10.0 0.1 13.0 0.6 2.9 2 1 1 3 3 3 0 Divalent cation transporter Ribosomal_S10 PF00338.22 RUS74472.1 - 8.3e-29 99.7 0.4 9.8e-29 99.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L7Ae PF01248.26 RUS74473.1 - 0.00061 19.5 0.2 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sulfotransfer_3 PF13469.6 RUS74474.1 - 1.5e-13 51.7 0.0 2.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS74474.1 - 3.2e-12 46.5 0.0 6.2e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Ig_3 PF13927.6 RUS74476.1 - 1.8e-48 163.0 4.6 9.4e-13 48.6 0.0 7.7 7 1 1 8 8 8 6 Immunoglobulin domain I-set PF07679.16 RUS74476.1 - 1.6e-35 121.0 0.0 2.7e-12 46.6 0.0 6.9 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS74476.1 - 1.6e-31 108.4 1.0 4.1e-09 36.7 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 RUS74476.1 - 8.1e-25 86.8 8.8 4.6e-08 33.1 0.0 7.3 7 1 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 RUS74476.1 - 6e-14 52.1 10.1 0.024 14.8 0.1 9.4 6 4 1 7 7 7 5 Immunoglobulin V-set domain fn3 PF00041.21 RUS74476.1 - 7.1e-14 51.9 15.1 2.5e-05 24.6 2.2 5.9 5 1 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS74476.1 - 0.00032 21.2 11.4 0.00069 20.1 1.0 4.2 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 RUS74476.1 - 0.0024 17.9 0.2 15 5.7 0.0 5.0 5 1 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS74476.1 - 0.005 16.8 0.1 23 5.1 0.0 4.1 4 0 0 4 4 4 0 C17orf99 Ig domain Lectin_C PF00059.21 RUS74476.1 - 0.054 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Lectin C-type domain Colicin_V PF02674.16 RUS74477.1 - 0.25 11.3 17.9 0.32 11.0 17.9 1.2 1 0 0 1 1 1 0 Colicin V production protein Grp7_allergen PF16984.5 RUS74477.1 - 0.89 9.6 10.1 5.1 7.1 2.2 2.2 1 1 1 2 2 2 0 Group 7 allergen ABC2_membrane PF01061.24 RUS74477.1 - 1.8 7.9 18.8 2.3 7.6 18.8 1.2 1 0 0 1 1 1 0 ABC-2 type transporter UPF0016 PF01169.19 RUS74477.1 - 5.3 7.5 24.2 1.2e+04 -3.3 24.2 2.5 1 1 0 1 1 1 0 Uncharacterized protein family UPF0016 PAN_1 PF00024.26 RUS74478.1 - 0.0035 17.3 0.0 0.0076 16.2 0.0 1.6 2 0 0 2 2 2 1 PAN domain Sushi PF00084.20 RUS74480.1 - 2.3e-08 34.5 0.2 4.3e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF2367 PF10164.9 RUS74480.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ras PF00071.22 RUS74481.1 - 1.5e-17 63.6 0.0 1.8e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS74481.1 - 4.2e-09 36.7 0.0 8.1e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS74481.1 - 0.0042 16.5 0.0 0.0048 16.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 RUS74481.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 RUS74481.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RUS74481.1 - 0.19 12.1 0.1 0.24 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zip PF02535.22 RUS74482.1 - 1.3e-50 172.6 3.1 1.5e-50 172.3 3.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ZIP4_domain PF18292.1 RUS74483.1 - 6e-05 23.0 9.5 0.16 11.9 0.1 3.6 3 1 2 5 5 5 4 Zinc transporter ZIP4 domain BUD22 PF09073.10 RUS74483.1 - 0.0056 16.1 1.7 0.0056 16.1 1.7 1.8 2 0 0 2 2 2 1 BUD22 CPSF100_C PF13299.6 RUS74483.1 - 0.55 10.4 1.9 61 3.7 0.0 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal STT3 PF02516.14 RUS74484.1 - 4.2e-146 487.7 38.3 4.6e-143 477.7 35.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF3283 PF11686.8 RUS74485.1 - 0.19 11.6 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Peptidase_C50 PF03568.17 RUS74486.1 - 1.7e-27 96.6 0.2 7.9e-27 94.4 0.1 2.2 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 RUS74486.1 - 0.03 13.8 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 CHAT domain SPRY PF00622.28 RUS74488.1 - 6.1e-05 23.1 0.0 0.00016 21.7 0.0 1.6 1 1 0 1 1 1 1 SPRY domain Nebulin PF00880.18 RUS74489.1 - 0.0031 17.4 0.1 0.0031 17.4 0.1 1.9 3 0 0 3 3 3 1 Nebulin repeat ARS2 PF04959.13 RUS74489.1 - 7.7 6.8 8.9 2 8.8 5.6 1.7 1 1 1 2 2 2 0 Arsenite-resistance protein 2 Sugar_tr PF00083.24 RUS74490.1 - 1.1e-24 87.2 14.7 1.6e-24 86.6 14.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS74490.1 - 3.1e-21 75.7 32.3 9.1e-21 74.2 31.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA_16 PF13191.6 RUS74491.1 - 0.00012 22.5 0.5 0.00041 20.8 0.5 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RUS74491.1 - 0.0045 16.9 2.1 0.022 14.7 1.2 2.7 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 RUS74491.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 RUS74491.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 RUS74492.1 - 0.0028 17.9 0.2 0.032 14.5 0.0 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RcpC PF16976.5 RUS74492.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB LRR_9 PF14580.6 RUS74493.1 - 3.8e-09 36.3 1.8 1.2e-08 34.7 1.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS74493.1 - 1.6e-06 27.7 9.2 0.0082 15.9 0.1 3.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RUS74493.1 - 3.2e-06 27.4 21.3 0.00017 21.9 6.5 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Not3 PF04065.15 RUS74494.1 - 1.3e-86 289.8 28.5 1.3e-86 289.8 28.5 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RUS74494.1 - 2.6e-40 137.5 11.5 1.4e-39 135.2 11.5 2.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family PRP38_assoc PF12871.7 RUS74494.1 - 1.7 9.3 12.1 12 6.6 0.6 2.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term IQ PF00612.27 RUS74495.1 - 0.002 17.7 3.4 0.006 16.3 3.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SH2 PF00017.24 RUS74496.1 - 7.3e-18 64.4 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 RUS74496.1 - 3.7e-17 62.7 4.9 5.7e-17 62.1 4.9 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS74496.1 - 1.5e-07 31.7 4.5 9.6e-07 29.2 4.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RUS74496.1 - 0.00096 19.4 1.3 0.0019 18.4 1.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 RUS74496.1 - 0.0015 18.9 2.2 0.061 13.7 2.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain SH2_2 PF14633.6 RUS74496.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 SH2 domain zf-Di19 PF05605.12 RUS74497.1 - 0.0012 19.1 2.6 0.0012 19.1 2.6 6.8 7 1 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 RUS74497.1 - 2.9 7.9 5.4 20 5.2 0.2 3.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Sulfotransfer_1 PF00685.27 RUS74498.1 - 4.5e-38 131.3 0.2 6.9e-38 130.6 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS74498.1 - 0.00063 20.2 0.4 0.0014 19.1 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family SRCR PF00530.18 RUS74499.1 - 3.5e-20 72.4 6.6 2.4e-12 47.2 2.4 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS74499.1 - 0.41 11.2 5.9 1.2 9.7 0.4 3.1 2 2 0 2 2 2 0 Scavenger receptor cysteine-rich domain F-box-like PF12937.7 RUS74501.1 - 5.9e-12 45.3 0.4 1.2e-11 44.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS74501.1 - 1.7e-10 40.5 1.0 3.7e-10 39.4 1.0 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 RUS74501.1 - 4.3e-07 30.5 4.7 0.22 12.5 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box_4 PF15966.5 RUS74501.1 - 0.029 14.3 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box Fer4 PF00037.27 RUS74502.1 - 3.5e-14 51.9 17.5 1.5e-08 34.1 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 RUS74502.1 - 1.8e-12 47.6 10.1 1.8e-12 47.6 10.1 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 RUS74502.1 - 3.6e-11 43.8 5.5 2.6e-05 25.1 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 RUS74502.1 - 7.1e-10 38.9 4.0 0.00018 21.6 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 RUS74502.1 - 1e-08 35.2 10.0 1.8e-08 34.4 10.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RUS74502.1 - 2e-08 34.2 21.4 6.9e-06 26.1 12.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 RUS74502.1 - 2.9e-07 30.3 17.8 0.00035 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 RUS74502.1 - 6.1e-07 29.8 19.6 0.00032 21.1 12.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 RUS74502.1 - 1e-06 28.4 12.1 0.0024 17.9 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 RUS74502.1 - 3.8e-06 27.0 10.7 0.0003 21.0 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 RUS74502.1 - 0.0002 21.8 10.9 0.042 14.4 12.6 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 RUS74502.1 - 0.011 16.3 14.6 0.58 10.7 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 RUS74502.1 - 0.018 15.3 7.3 0.65 10.3 0.4 2.5 2 1 1 3 3 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.7 RUS74502.1 - 0.15 13.1 16.3 0.31 12.1 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 RUS74502.1 - 0.15 12.3 11.4 0.91 9.7 1.4 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 RUS74502.1 - 0.24 11.5 5.8 1.2 9.3 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 RUS74502.1 - 0.63 10.9 11.8 2.7 8.9 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain PseudoU_synth_2 PF00849.22 RUS74503.1 - 4.7e-05 23.5 0.0 6.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_2 PF00849.22 RUS74504.1 - 2.6e-08 34.1 0.0 1.9e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 RNA pseudouridylate synthase Sulfotransfer_1 PF00685.27 RUS74505.1 - 9e-07 28.6 0.0 9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Omp28 PF11551.8 RUS74506.1 - 0.00049 20.0 6.1 0.76 9.6 0.5 3.9 1 1 3 4 4 4 3 Outer membrane protein Omp28 zf-HC5HC2H PF13771.6 RUS74506.1 - 0.0063 16.7 15.3 2.4 8.5 1.6 3.8 1 1 3 4 4 4 4 PHD-like zinc-binding domain CDH PF02611.15 RUS74506.1 - 0.013 15.2 8.9 1.8 8.2 0.2 3.7 1 1 2 4 4 4 0 CDP-diacylglycerol pyrophosphatase Cadherin-like PF12733.7 RUS74506.1 - 0.028 15.0 0.5 2.3 8.8 0.1 2.9 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Fis1_TPR_N PF14852.6 RUS74506.1 - 0.13 12.0 12.6 2.5e+02 1.5 0.0 8.0 10 0 0 10 10 10 0 Fis1 N-terminal tetratricopeptide repeat EIF_2_alpha PF07541.12 RUS74506.1 - 0.26 11.4 13.8 38 4.4 0.1 6.0 1 1 4 5 5 5 0 Eukaryotic translation initiation factor 2 alpha subunit zinc-ribbons_6 PF07191.12 RUS74506.1 - 0.81 9.7 23.1 80 3.3 3.0 4.3 1 1 1 2 2 2 0 zinc-ribbons DUF4562 PF15123.6 RUS74507.1 - 2.6e-12 46.7 0.0 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) DIRP PF06584.13 RUS74508.1 - 6.3e-43 145.3 0.2 1.7e-42 143.9 0.2 1.8 1 0 0 1 1 1 1 DIRP Laminin_EGF PF00053.24 RUS74509.1 - 0.00011 22.2 24.8 0.0013 18.8 10.9 5.7 3 1 2 5 5 5 2 Laminin EGF domain EGF_CA PF07645.15 RUS74509.1 - 0.0022 18.2 16.8 0.0022 18.2 16.8 5.1 1 1 3 4 4 4 1 Calcium-binding EGF domain EGF_2 PF07974.13 RUS74509.1 - 0.0053 17.1 2.3 0.0053 17.1 2.3 7.3 4 3 3 7 7 7 3 EGF-like domain EGF_3 PF12947.7 RUS74509.1 - 0.01 16.0 5.2 0.01 16.0 5.2 5.9 2 2 1 4 4 4 0 EGF domain EGF PF00008.27 RUS74509.1 - 0.046 14.0 63.6 0.052 13.9 7.7 5.7 4 2 0 4 4 4 0 EGF-like domain Neur_chan_LBD PF02931.23 RUS74510.1 - 9.5e-39 133.1 0.0 3.3e-38 131.3 0.0 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74510.1 - 1.1e-24 87.8 0.7 2e-24 87.0 0.7 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_8 PF01270.17 RUS74511.1 - 0.21 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 ANTH PF07651.16 RUS74512.1 - 1.7e-62 210.9 0.0 1.7e-62 210.9 0.0 2.0 2 0 0 2 2 2 1 ANTH domain ATG16 PF08614.11 RUS74512.1 - 0.014 15.7 17.0 0.014 15.7 17.0 2.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CorA PF01544.18 RUS74512.1 - 0.14 11.5 12.6 0.036 13.4 7.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3914 PF13053.6 RUS74512.1 - 0.16 12.4 4.1 0.11 12.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) Calpain_inhib PF00748.19 RUS74512.1 - 0.18 12.3 15.1 0.25 11.9 0.4 2.4 2 0 0 2 2 2 0 Calpain inhibitor Viral_env_E26 PF11050.8 RUS74512.1 - 0.19 11.0 4.3 0.064 12.6 1.4 1.6 2 0 0 2 2 2 0 Virus envelope protein E26 MctB PF11382.8 RUS74512.1 - 0.23 11.1 2.7 0.26 11.0 1.6 1.5 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB TPR_MLP1_2 PF07926.12 RUS74512.1 - 1.6 8.8 24.3 1.7 8.7 16.5 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 RUS74512.1 - 2.6 6.9 22.1 4 6.2 21.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein PI3Ka PF00613.20 RUS74517.1 - 2.8e-29 101.8 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RUS74518.1 - 7.3e-42 143.9 0.2 3.6e-28 99.0 0.1 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 RUS74518.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CPSase_L_D2 PF02786.17 RUS74519.1 - 2.1e-75 252.8 0.1 4.3e-75 251.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 RUS74519.1 - 6.5e-36 122.7 0.0 2.1e-35 121.1 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RUS74519.1 - 1.1e-15 57.2 3.6 5.2e-15 55.0 3.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_N PF00289.22 RUS74519.1 - 4.4e-14 52.9 0.4 1.2e-12 48.3 0.1 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 RUS74519.1 - 2.7e-11 43.4 0.1 8.1e-11 41.8 0.1 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RUS74519.1 - 7.6e-09 35.4 0.2 1.3e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 RUS74519.1 - 2.1e-08 33.9 2.6 0.0019 18.0 0.1 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 RUS74519.1 - 7.4e-06 26.1 0.1 1.9e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 RUS74519.1 - 6.2e-05 23.7 0.4 0.073 13.8 0.0 3.0 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 RUS74519.1 - 9.7e-05 21.7 0.4 0.25 10.5 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 RUS74519.1 - 0.0001 21.7 0.2 0.0057 16.0 0.1 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF4140 PF13600.6 RUS74519.1 - 0.016 15.6 0.1 0.063 13.7 0.1 2.0 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RimK PF08443.11 RUS74519.1 - 0.046 13.3 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain PASTA PF03793.19 RUS74519.1 - 0.14 12.0 1.1 5.1 7.0 0.2 2.8 2 0 0 2 2 2 0 PASTA domain YqfD PF06898.11 RUS74519.1 - 0.34 9.7 1.4 2.5 6.8 0.1 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD DUF1240 PF06836.12 RUS74520.1 - 0.00064 20.2 0.3 1.1e+02 3.4 0.0 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1240) LRR_5 PF13306.6 RUS74520.1 - 0.0009 19.2 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) KSHV_K1 PF11049.8 RUS74520.1 - 0.0016 18.3 9.5 6.6 6.8 0.1 4.9 1 1 4 5 5 5 3 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus TPR_11 PF13414.6 RUS74520.1 - 0.78 9.5 4.1 1.4e+02 2.2 0.1 3.9 4 0 0 4 4 4 0 TPR repeat CBM_14 PF01607.24 RUS74521.1 - 2.8e-83 274.0 71.1 7.3e-12 45.3 2.0 8.4 8 0 0 8 8 8 8 Chitin binding Peritrophin-A domain RVT_1 PF00078.27 RUS74522.1 - 5.8e-46 156.8 1.2 7.2e-46 156.5 1.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C65 PF10275.9 RUS74522.1 - 0.011 15.2 0.4 0.023 14.2 0.4 1.5 1 0 0 1 1 1 0 Peptidase C65 Otubain RNA_bind PF08675.11 RUS74523.1 - 0.00034 20.6 0.4 34 4.6 0.0 5.6 2 1 3 5 5 5 2 RNA binding domain Mito_carr PF00153.27 RUS74525.1 - 9.9e-60 198.5 7.7 1.5e-20 72.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GalKase_gal_bdg PF10509.9 RUS74526.1 - 2.3e-21 75.1 0.1 4.9e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RUS74526.1 - 2.3e-12 47.1 0.0 6.3e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RUS74526.1 - 8.2e-11 42.0 1.3 9.5e-11 41.8 0.1 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain OspE PF02471.17 RUS74526.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Borrelia outer surface protein E rve PF00665.26 RUS74527.1 - 1e-19 70.9 0.0 1.8e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS74527.1 - 1.2e-09 38.1 1.1 2.5e-09 37.1 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RUS74527.1 - 0.00017 21.3 0.0 0.00054 19.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 RUS74527.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PIN_5 PF08745.11 RUS74527.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease GalKase_gal_bdg PF10509.9 RUS74528.1 - 1e-21 76.2 0.0 1.9e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RUS74528.1 - 2.3e-13 50.3 0.0 5.5e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RUS74528.1 - 1.2e-09 38.3 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GreA_GreB_N PF03449.15 RUS74528.1 - 0.042 14.0 0.5 0.1 12.8 0.5 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF3372 PF11852.8 RUS74529.1 - 0.25 10.8 1.7 2.7 7.4 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3372) HLH PF00010.26 RUS74530.1 - 7.4e-10 38.6 0.3 1.5e-09 37.6 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_DBD PF16422.5 RUS74532.1 - 1.9e-134 446.4 0.9 2.4e-134 446.0 0.9 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 RUS74532.1 - 1.1e-30 105.0 0.6 2.1e-30 104.2 0.6 1.5 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 RUS74532.1 - 1e-11 44.7 0.9 1.9e-11 43.9 0.2 1.9 2 0 0 2 2 2 1 IPT/TIG domain ESP PF16590.5 RUS74533.1 - 0.87 9.9 6.0 0.31 11.3 0.3 3.0 3 0 0 3 3 3 0 Exocrine gland-secreting peptide DNA_pol_A_exo1 PF01612.20 RUS74534.1 - 2.9e-17 62.9 0.0 5.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Ribosomal_S14 PF00253.21 RUS74534.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e AC_N PF16214.5 RUS74535.1 - 0.25 10.4 5.6 0.3 10.2 5.6 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region LRR_8 PF13855.6 RUS74537.1 - 3.4e-22 78.0 11.4 2.2e-10 40.1 0.3 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS74537.1 - 1.8e-17 63.1 21.2 3.4e-07 30.5 0.3 4.8 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS74537.1 - 0.0016 17.9 2.3 0.63 9.5 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RUS74537.1 - 0.075 13.6 19.9 11 7.1 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_5 PF13306.6 RUS74537.1 - 0.11 12.5 3.0 0.32 10.9 0.3 2.7 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS74537.1 - 3.9 7.8 14.8 27 5.1 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich repeat Suppressor_APC PF11414.8 RUS74539.1 - 1.5e-23 82.6 3.7 1.5e-23 82.6 3.7 2.6 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein EF-hand_6 PF13405.6 RUS74539.1 - 0.027 14.4 0.1 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain bZIP_1 PF00170.21 RUS74539.1 - 0.13 12.3 3.2 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 RUS74539.1 - 0.14 11.0 11.2 0.38 9.6 2.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 RUS74539.1 - 0.28 11.4 6.8 3.8 7.8 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fungal_TACC PF12709.7 RUS74539.1 - 0.72 10.3 5.0 0.2 12.1 0.9 2.2 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spore_III_AF PF09581.10 RUS74539.1 - 0.82 9.7 2.4 0.93 9.5 0.6 1.8 1 1 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) GAS PF13851.6 RUS74539.1 - 1.2 8.4 7.1 2.5 7.4 0.4 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 RUS74539.1 - 1.4 9.4 8.7 1 9.9 0.6 3.0 2 1 0 2 2 2 0 Spectrin repeat DUF4407 PF14362.6 RUS74539.1 - 2.2 7.6 8.0 4.5 6.5 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 RUS74539.1 - 2.5 8.6 10.5 78 3.8 9.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 RUS74539.1 - 8 6.5 6.7 2.5 8.2 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Galactosyl_T PF01762.21 RUS74540.1 - 4.4e-08 33.2 0.0 5.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sec1 PF00995.23 RUS74543.1 - 5.6e-127 425.4 0.3 6.3e-127 425.2 0.3 1.0 1 0 0 1 1 1 1 Sec1 family YscO PF07321.12 RUS74543.1 - 0.13 12.2 3.6 0.73 9.8 4.1 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO YlbD_coat PF14071.6 RUS74543.1 - 4.2 7.6 7.6 5.3 7.3 5.1 2.4 2 0 0 2 2 2 0 Putative coat protein Ribosomal_L7Ae PF01248.26 RUS74545.1 - 5.6e-23 80.5 0.0 1.3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.6 RUS74545.1 - 0.0084 16.3 1.4 0.075 13.2 1.3 2.1 2 0 0 2 2 2 1 Heavy-metal resistance Lung_7-TM_R PF06814.13 RUS74547.1 - 3.6e-68 230.0 20.3 3.6e-68 230.0 20.3 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 RUS74547.1 - 2.5e-08 33.6 18.8 5.5e-08 32.5 18.8 1.5 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain MID_MedPIWI PF18296.1 RUS74547.1 - 0.009 15.8 0.7 0.069 12.9 0.5 2.0 2 0 0 2 2 2 1 MID domain of medPIWI Pkinase_Tyr PF07714.17 RUS74549.1 - 1.1e-94 316.6 0.0 1.6e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS74549.1 - 2.3e-48 164.9 0.0 3.5e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS74549.1 - 5.1e-24 84.2 0.2 1.3e-23 82.9 0.2 1.8 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 RUS74549.1 - 6e-16 58.5 0.3 1.4e-15 57.4 0.3 1.7 1 0 0 1 1 1 1 F-actin binding SH3_1 PF00018.28 RUS74549.1 - 1.7e-10 40.4 0.0 3.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS74549.1 - 7.3e-08 32.1 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 RUS74549.1 - 0.0036 17.6 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 RUS74549.1 - 0.0062 15.5 0.0 0.018 14.0 0.0 1.8 1 0 0 1 1 1 1 Haspin like kinase domain SH3_4 PF06347.13 RUS74549.1 - 0.053 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Evr1_Alr PF04777.13 RUS74550.1 - 1.1e-26 93.2 0.1 3.7e-26 91.5 0.1 2.0 1 0 0 1 1 1 1 Erv1 / Alr family FAD_SOX PF18371.1 RUS74550.1 - 3.4e-25 88.4 0.0 1.1e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Thioredoxin PF00085.20 RUS74550.1 - 7.3e-18 64.5 0.4 8.2e-17 61.1 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin QSOX_Trx1 PF18108.1 RUS74550.1 - 7.4e-10 39.0 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 QSOX Trx-like domain DUF35_N PF12172.8 RUS74550.1 - 0.0022 17.8 1.0 0.0078 16.1 1.0 2.0 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Thioredoxin_8 PF13905.6 RUS74550.1 - 0.0038 17.5 0.5 0.023 15.0 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 RUS74550.1 - 0.011 15.2 1.3 0.019 14.3 0.1 1.9 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 RUS74550.1 - 0.085 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 RUS74550.1 - 0.15 12.6 0.2 2.4 8.6 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.25 RUS74551.1 - 8.9e-40 136.7 0.2 1.4e-39 136.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74551.1 - 2.1e-20 73.1 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS74551.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Prolamin_like PF05617.11 RUS74551.1 - 0.25 11.6 3.0 0.53 10.5 0.7 2.5 2 0 0 2 2 2 0 Prolamin-like LTP_2 PF14368.6 RUS74551.1 - 1.2 9.3 6.5 0.32 11.1 2.2 2.2 1 1 0 2 2 2 0 Probable lipid transfer DEFB136 PF17333.2 RUS74553.1 - 0.00019 21.3 19.6 1 9.4 0.1 5.1 4 1 1 5 5 5 4 Beta defensin 136 DSL PF01414.19 RUS74553.1 - 0.00062 20.0 34.7 0.0045 17.2 12.7 4.3 3 1 1 4 4 4 2 Delta serrate ligand Dymeclin PF09742.9 RUS74554.1 - 3.1e-25 88.7 0.0 3.6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Dymeclin PF09742.9 RUS74555.1 - 4.7e-27 94.7 0.0 5.2e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Pheromone PF08015.11 RUS74556.1 - 7.7 7.6 0.0 7.7 7.6 0.0 4.4 3 1 0 3 3 3 0 Fungal mating-type pheromone Cornifin PF02389.15 RUS74557.1 - 6.1e-05 23.2 8.0 6.1e-05 23.2 8.0 1.8 2 0 0 2 2 2 1 Cornifin (SPRR) family pP_pnuc_2 PF18166.1 RUS74557.1 - 0.074 13.1 3.6 2.2 8.4 1.2 2.9 2 1 1 3 3 3 0 Predicted pPIWI-associating nuclease EnY2 PF10163.9 RUS74557.1 - 0.35 11.3 15.0 1.3 9.4 7.5 2.4 1 1 1 2 2 2 0 Transcription factor e(y)2 EcsC PF12787.7 RUS74557.1 - 0.52 10.0 9.9 3.9 7.1 9.7 2.2 1 1 0 1 1 1 0 EcsC protein family YpjP PF14005.6 RUS74557.1 - 0.52 10.4 9.1 1.4 8.9 8.9 1.8 1 1 0 1 1 1 0 YpjP-like protein DUF2115 PF09888.9 RUS74557.1 - 1.3 9.5 7.5 2.4 8.7 7.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF802 PF05650.11 RUS74557.1 - 4.5 7.8 7.5 0.73 10.3 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF802) VitD-bind_III PF09164.10 RUS74557.1 - 10 6.2 8.4 3.7e+02 1.2 5.9 3.4 2 1 0 2 2 2 0 Vitamin D binding protein, domain III Mito_carr PF00153.27 RUS74559.1 - 7.3e-25 86.7 0.3 2.8e-14 52.8 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein RHD_DNA_bind PF00554.22 RUS74561.1 - 2.1e-66 223.0 1.1 3.3e-66 222.4 1.1 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 RUS74561.1 - 9.4e-39 131.6 0.0 1.8e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain EF-hand_1 PF00036.32 RUS74563.1 - 6.7e-06 25.3 0.2 6e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS74563.1 - 4.1e-05 23.2 0.1 0.0033 17.2 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RUS74563.1 - 5.5e-05 23.5 0.1 0.024 15.1 0.0 3.0 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS74563.1 - 0.00029 20.6 0.3 0.0057 16.5 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS74563.1 - 0.0018 17.7 0.2 0.015 14.8 0.1 2.2 2 0 0 2 2 2 1 EF hand IBN_N PF03810.19 RUS74563.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain LCD1 PF09798.9 RUS74563.1 - 0.8 8.1 5.5 1 7.8 5.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SH3_9 PF14604.6 RUS74564.1 - 8.9e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS74564.1 - 2.7e-06 26.9 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS74564.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2013 PF09431.10 RUS74566.1 - 2.6e-06 27.7 0.5 3.2e-06 27.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF1151 PF06625.11 RUS74567.1 - 6.3e-20 71.2 9.1 1.1e-19 70.5 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) TMEM171 PF15471.6 RUS74567.1 - 0.17 10.8 1.0 0.45 9.5 0.3 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF1180 PF06679.12 RUS74567.1 - 2 8.8 4.7 3.1 8.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DIM1 PF02966.16 RUS74568.1 - 1e-52 177.4 0.0 1.2e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 RUS74568.1 - 9.7e-05 22.3 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Laps PF10169.9 RUS74569.1 - 1.2e-22 80.8 21.4 2.8e-22 79.6 21.4 1.5 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 RUS74569.1 - 8.8e-06 25.9 6.3 8.8e-06 25.9 6.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Josephin PF02099.17 RUS74569.1 - 0.043 13.9 1.1 0.048 13.8 1.1 1.2 1 0 0 1 1 1 0 Josephin UPF0114 PF03350.16 RUS74569.1 - 0.27 11.4 0.4 0.52 10.5 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 CaM_binding PF07839.11 RUS74569.1 - 0.37 11.5 13.8 0.58 10.9 13.8 1.3 1 1 0 1 1 1 0 Plant calmodulin-binding domain Rotamase PF00639.21 RUS74569.1 - 1.5 9.9 8.2 3 8.9 8.2 1.6 1 1 0 1 1 1 0 PPIC-type PPIASE domain Actin PF00022.19 RUS74570.1 - 6.1e-35 120.6 0.0 1.8e-17 63.1 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 RUS74570.1 - 7.1e-09 35.3 1.5 0.00077 18.7 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family TMEM154 PF15102.6 RUS74571.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.3 3 0 0 3 3 3 0 TMEM154 protein family VEGFR-2_TMD PF17988.1 RUS74571.1 - 0.17 11.3 5.2 0.34 10.4 5.2 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain EphA2_TM PF14575.6 RUS74571.1 - 0.35 11.8 1.0 1.8 9.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CPG4 PF15481.6 RUS74572.1 - 0.0057 17.3 10.3 0.83 10.3 5.6 2.6 2 1 0 2 2 2 2 Chondroitin proteoglycan 4 Pyr_redox_2 PF07992.14 RUS74573.1 - 6.8e-46 156.8 0.0 8e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS74573.1 - 8.7e-08 32.6 0.2 2.9e-07 31.0 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SAC3_GANP PF03399.16 RUS74574.1 - 8.4e-106 353.6 5.6 1.7e-105 352.6 5.6 1.5 1 0 0 1 1 1 1 SAC3/GANP family RRM_1 PF00076.22 RUS74574.1 - 0.00035 20.3 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoporin_FG PF13634.6 RUS74574.1 - 0.0068 17.2 58.0 0.013 16.3 20.9 4.4 1 1 3 4 4 4 3 Nucleoporin FG repeat region DUF2884 PF11101.8 RUS74574.1 - 0.1 12.1 7.7 0.19 11.2 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MCM3AP_GANP PF16769.5 RUS74575.1 - 7.8e-75 252.5 17.6 2.6e-74 250.8 17.6 1.7 1 1 0 1 1 1 1 MCM3AP domain of GANP FAM194 PF14977.6 RUS74576.1 - 1.5e-13 50.5 0.0 3.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 FAM194 protein RNase_H2-Ydr279 PF09468.10 RUS74576.1 - 0.00038 20.7 0.2 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ribosomal_L6e PF01159.19 RUS74576.1 - 0.82 10.2 5.1 0.8 10.3 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein L6e D123 PF07065.14 RUS74577.1 - 2.8e-97 325.6 1.4 4.3e-97 324.9 1.4 1.3 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 RUS74577.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 RUS74577.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 START PF01852.19 RUS74578.1 - 7.3e-27 94.1 0.0 9e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 START domain GCV_T PF01571.21 RUS74580.1 - 6.4e-88 294.4 0.0 7.9e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RUS74580.1 - 4.2e-18 65.0 0.0 7.8e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF693 PF05113.13 RUS74580.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) ING PF12998.7 RUS74581.1 - 4.7e-29 100.9 9.7 4.7e-29 100.9 9.7 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RUS74581.1 - 4.2e-06 26.6 6.8 4.2e-06 26.6 6.8 1.8 2 0 0 2 2 2 1 PHD-finger Myosin_tail_1 PF01576.19 RUS74581.1 - 3.8e-05 21.7 12.3 5.9e-05 21.1 12.3 1.3 1 0 0 1 1 1 1 Myosin tail DUF1919 PF08942.10 RUS74581.1 - 0.0032 16.9 1.7 0.0059 16.1 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1919) 7TMR-HDED PF07697.11 RUS74581.1 - 0.0055 16.9 0.9 0.02 15.0 1.0 1.8 1 1 0 1 1 1 1 7TM-HD extracellular DUF1819 PF08849.11 RUS74581.1 - 0.006 16.4 1.5 0.006 16.4 1.5 1.8 2 0 0 2 2 2 1 Putative inner membrane protein (DUF1819) DUF4375 PF14300.6 RUS74581.1 - 0.25 11.6 3.5 0.7 10.2 3.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Aminotran_4 PF01063.19 RUS74581.1 - 0.32 10.8 4.1 1.5 8.6 0.1 2.3 1 1 0 2 2 2 0 Amino-transferase class IV zf-HC5HC2H PF13771.6 RUS74581.1 - 0.67 10.2 6.7 0.14 12.4 0.7 2.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain ApoC-I PF04691.12 RUS74581.1 - 1.3 9.0 7.6 4.3 7.3 2.7 3.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) DUF334 PF03904.13 RUS74581.1 - 2.4 7.6 8.2 4 6.9 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Usp PF00582.26 RUS74582.1 - 9.3e-05 23.0 0.0 0.044 14.3 0.0 2.2 2 0 0 2 2 2 2 Universal stress protein family zf-H2C2_2 PF13465.6 RUS74583.1 - 2.1e-14 53.2 40.0 7.5e-06 26.1 0.2 8.4 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS74583.1 - 1.8e-12 46.9 54.0 0.023 15.5 0.3 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS74583.1 - 5.1e-11 42.4 55.6 0.0016 18.8 0.5 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.7 RUS74583.1 - 8.1e-06 26.1 26.8 0.01 16.2 0.2 6.2 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS74583.1 - 5.7e-05 23.3 15.4 0.095 13.0 0.2 5.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS74583.1 - 0.00042 20.6 36.9 0.23 11.8 0.0 7.9 3 2 3 6 6 6 3 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 RUS74583.1 - 0.024 14.4 0.8 0.024 14.4 0.8 3.9 3 1 1 4 4 4 0 GAGA factor zf-Di19 PF05605.12 RUS74583.1 - 0.057 13.7 31.6 0.036 14.4 4.2 5.5 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS74583.1 - 0.37 11.5 23.0 5.1 7.8 0.2 5.4 3 1 3 6 6 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 RUS74583.1 - 2.3 8.1 21.2 2.2 8.2 0.0 5.7 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 RUS74583.1 - 3 8.0 39.6 0.15 12.1 0.8 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 RUS74583.1 - 7.9 6.1 14.7 1.6 8.3 0.1 4.1 3 1 1 4 4 4 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RUS74584.1 - 6.8e-30 102.2 54.0 1.1e-07 31.9 1.0 8.2 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 RUS74584.1 - 3.3e-25 87.1 49.6 2.4e-06 27.7 0.4 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS74584.1 - 9.5e-25 85.2 50.9 6.8e-05 23.4 0.6 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS74584.1 - 2.2e-10 40.3 43.2 0.00086 19.2 0.3 7.9 8 0 0 8 8 8 4 C2H2-type zinc finger zf-met PF12874.7 RUS74584.1 - 8.1e-09 35.6 36.9 0.0027 18.1 0.6 7.9 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS74584.1 - 1.3e-06 28.5 36.0 0.013 15.7 0.1 7.7 9 0 0 9 9 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS74584.1 - 0.00012 22.3 33.0 0.15 12.4 1.7 5.2 2 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 RUS74584.1 - 0.00035 20.9 38.3 0.21 12.0 11.6 6.3 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 RUS74584.1 - 0.00052 19.8 7.1 0.1 12.4 0.1 3.1 2 0 0 2 2 2 2 GAGA factor C1_1 PF00130.22 RUS74584.1 - 0.065 13.1 29.1 0.91 9.5 0.8 5.7 2 2 3 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-C2H2_12 PF18112.1 RUS74584.1 - 0.18 12.3 0.1 0.18 12.3 0.1 5.9 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 RUS74584.1 - 0.22 12.3 26.3 10 6.9 6.9 4.2 1 1 3 4 4 4 0 zinc-ribbon family Zf_RING PF16744.5 RUS74584.1 - 1.7 8.8 29.8 1 9.6 0.2 5.6 1 1 4 5 5 5 0 KIAA1045 RING finger BolA PF01722.18 RUS74584.1 - 2 8.7 6.3 25 5.3 0.1 3.8 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_8 PF15909.5 RUS74584.1 - 3.1 8.2 25.2 6.2 7.2 5.0 4.3 1 1 2 4 4 4 0 C2H2-type zinc ribbon zf-RRPl_C4 PF17026.5 RUS74584.1 - 4.1 7.5 23.1 2.1 8.5 6.1 3.4 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2_9 PF16293.5 RUS74584.1 - 5.8 6.8 20.4 0.91 9.4 0.1 5.7 5 2 1 6 6 6 0 C2H2 type zinc-finger (1 copy) PHD PF00628.29 RUS74584.1 - 9.4 6.2 32.7 1.2 9.1 4.6 4.8 3 2 0 3 3 3 0 PHD-finger Y_phosphatase PF00102.27 RUS74585.1 - 8.7e-126 418.2 0.8 2.1e-83 279.5 1.8 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RUS74585.1 - 1.4e-50 169.6 8.1 1.5e-16 60.5 0.2 5.2 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS74585.1 - 1.9e-11 44.4 0.1 0.0036 17.8 0.0 5.4 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 RUS74585.1 - 7.1e-06 26.1 0.1 1 9.6 0.0 3.8 3 0 0 3 3 3 2 Fibronectin type III domain Y_phosphatase3 PF13350.6 RUS74585.1 - 3.9e-05 23.7 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Interfer-bind PF09294.10 RUS74585.1 - 0.00086 19.6 0.0 5.7 7.3 0.0 3.8 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 RUS74585.1 - 0.0031 17.3 0.0 0.0089 15.8 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS74585.1 - 0.0047 17.1 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2369 PF10179.9 RUS74585.1 - 0.025 14.9 0.0 75 3.8 0.0 4.2 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 RUS74585.1 - 0.11 12.4 0.6 47 4.0 0.0 4.4 4 2 0 4 4 4 0 Fibronectin-III type domain zinc_ribbon_13 PF09855.9 RUS74586.1 - 0.036 14.2 0.4 0.081 13.1 0.4 1.6 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Nup54 PF13874.6 RUS74586.1 - 0.15 12.2 9.0 7.2 6.7 10.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 zf-TRAF PF02176.18 RUS74586.1 - 0.17 12.6 4.6 1 10.1 3.2 2.7 2 1 0 2 2 2 0 TRAF-type zinc finger V_ATPase_I PF01496.19 RUS74587.1 - 0 1014.4 6.5 0 1013.9 6.5 1.2 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RUS74587.1 - 0.92 10.0 5.3 2.2 8.8 5.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DHR10 PF18595.1 RUS74587.1 - 1.7 8.7 8.8 0.13 12.4 0.8 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 RUS74587.1 - 1.8 9.0 8.5 0.75 10.2 1.5 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Bcl-2 PF00452.19 RUS74588.1 - 8.8e-22 77.7 0.2 2.4e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family BILBO1_N PF18281.1 RUS74588.1 - 0.0022 18.4 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 BILBO1 N-terminal domain PLDc_2 PF13091.6 RUS74590.1 - 7.8e-30 103.5 0.2 1.5e-29 102.5 0.1 1.5 2 0 0 2 2 2 1 PLD-like domain FAM83 PF07894.12 RUS74590.1 - 0.00028 20.6 1.5 0.0064 16.1 0.1 2.4 2 1 0 2 2 2 2 FAM83 A-H PLDc PF00614.22 RUS74590.1 - 0.008 16.3 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Phospholipase D Active site motif Endonuc-BglII PF09195.11 RUS74590.1 - 0.087 12.7 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease BglII DUF846 PF05832.12 RUS74591.1 - 3.3e-52 176.2 14.9 4.1e-52 175.9 14.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2868 PF11067.8 RUS74591.1 - 0.82 9.1 4.8 0.11 12.0 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) PPR_2 PF13041.6 RUS74592.1 - 2.5e-22 78.8 0.1 6.4e-07 29.5 0.0 6.7 5 3 2 7 7 7 4 PPR repeat family PPR_3 PF13812.6 RUS74592.1 - 6.4e-18 64.6 0.0 0.00053 20.0 0.0 5.3 3 1 3 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 RUS74592.1 - 6.9e-09 35.4 0.0 0.00082 18.8 0.0 3.3 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 RUS74592.1 - 4.6e-08 32.6 0.8 0.0025 17.5 0.1 5.6 7 0 0 7 7 7 2 PPR repeat PPR PF01535.20 RUS74592.1 - 4e-07 29.8 10.6 0.00043 20.3 0.1 5.8 7 0 0 7 7 7 2 PPR repeat ECSIT PF06239.11 RUS74592.1 - 1.2 8.2 5.2 5.6 6.0 0.1 3.2 4 1 1 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway Thioredoxin_7 PF13899.6 RUS74593.1 - 4.7e-14 52.3 0.1 6.3e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 RUS74593.1 - 2.4e-05 24.4 0.7 3.8e-05 23.7 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Ifi-6-16 PF06140.13 RUS74594.1 - 9.7e-13 47.8 33.4 1.6e-12 47.2 33.2 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family Thioredoxin_7 PF13899.6 RUS74595.1 - 4.3e-11 42.9 0.0 6.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS74595.1 - 1e-06 29.2 0.0 1.5e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 RUS74595.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin DUF836 PF05768.14 RUS74595.1 - 0.07 13.5 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) ASC PF00858.24 RUS74596.1 - 9.3e-05 21.6 0.3 0.00012 21.2 0.0 1.4 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS74597.1 - 5.6e-18 65.1 1.4 1.1e-17 64.1 1.4 1.7 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Neur_chan_LBD PF02931.23 RUS74599.1 - 5.5e-70 235.2 3.0 5.5e-70 235.2 2.1 1.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74599.1 - 4.1e-42 144.9 0.0 8.7e-42 143.8 0.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 RUS74599.1 - 4.8 6.5 8.2 1.5 8.2 3.2 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) zf-RING_2 PF13639.6 RUS74600.1 - 8e-09 35.7 9.9 1.5e-08 34.8 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS74600.1 - 2.5e-07 30.5 10.8 5e-07 29.5 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS74600.1 - 7.5e-07 29.0 11.3 1.6e-06 27.9 11.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS74600.1 - 1.5e-06 28.0 11.9 6.3e-06 25.9 11.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS74600.1 - 2.9e-06 27.0 10.2 6.6e-06 25.9 10.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS74600.1 - 4.6e-06 26.6 4.4 4.6e-06 26.6 4.4 1.9 2 1 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS74600.1 - 5.7e-05 22.9 10.7 8e-05 22.4 4.7 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RUS74600.1 - 0.00065 19.9 10.5 0.0019 18.5 10.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RUS74600.1 - 0.001 18.8 7.6 0.0019 18.0 7.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 RUS74600.1 - 0.021 15.0 11.5 0.43 10.8 11.7 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 RUS74600.1 - 0.05 12.9 3.6 0.043 13.2 2.4 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 RUS74600.1 - 0.064 13.0 3.7 0.11 12.3 1.5 2.5 2 1 1 3 3 3 0 RING-like zinc finger zf-RING_10 PF16685.5 RUS74600.1 - 0.1 12.8 8.2 0.33 11.1 8.3 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-UDP PF14569.6 RUS74600.1 - 0.1 12.7 3.6 0.2 11.8 3.6 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc-ribbons_6 PF07191.12 RUS74600.1 - 0.12 12.4 6.8 0.24 11.4 6.8 1.5 1 1 0 1 1 1 0 zinc-ribbons zf-Nse PF11789.8 RUS74600.1 - 0.29 11.0 9.0 0.8 9.6 9.0 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 RUS74600.1 - 0.33 10.9 7.2 0.85 9.6 7.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 RUS74600.1 - 0.53 10.4 6.5 1.1 9.3 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-LITAF-like PF10601.9 RUS74600.1 - 2.1 8.7 9.5 13 6.1 9.5 2.0 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-P11 PF03854.14 RUS74600.1 - 2.4 7.9 6.5 1.1 8.9 1.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger Cys_rich_KTR PF14205.6 RUS74600.1 - 7.4 6.5 9.2 97 2.9 9.2 2.5 1 1 0 1 1 1 0 Cysteine-rich KTR TGS PF02824.21 RUS74601.1 - 1.3e-14 54.0 0.0 2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain I-set PF07679.16 RUS74602.1 - 2e-38 130.4 0.0 6.8e-16 58.1 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74602.1 - 3.1e-34 117.4 0.0 2.1e-14 53.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain TSP_1 PF00090.19 RUS74602.1 - 3.6e-32 110.4 49.5 6.9e-13 48.6 9.5 3.8 4 0 0 4 4 4 3 Thrombospondin type 1 domain Ig_2 PF13895.6 RUS74602.1 - 4e-19 68.7 0.0 6.9e-09 35.9 0.0 3.5 2 1 1 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS74602.1 - 1.2e-17 63.8 0.0 9.1e-08 32.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS74602.1 - 1.1e-09 38.4 0.9 0.13 12.5 0.1 5.1 3 2 0 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS74602.1 - 8.2e-06 25.3 0.0 1.2 8.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 RUS74602.1 - 8.7e-06 25.7 0.0 0.074 13.1 0.0 2.8 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 RUS74602.1 - 0.036 14.1 0.0 6.2 6.9 0.0 3.0 3 0 0 3 3 3 0 C17orf99 Ig domain DUF3432 PF11914.8 RUS74603.1 - 0.6 10.4 42.5 0.91 9.8 13.4 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3432) RRM_1 PF00076.22 RUS74605.1 - 2.5e-08 33.6 0.0 5.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS74605.1 - 0.0019 17.8 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.13 RUS74605.1 - 0.0037 17.9 4.3 0.0087 16.7 0.1 2.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1737 PF08410.10 RUS74605.1 - 0.17 11.8 0.1 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) Neur_chan_LBD PF02931.23 RUS74606.1 - 2.2e-30 105.7 0.5 2.9e-30 105.3 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74606.1 - 1.1e-08 35.5 0.0 0.0042 17.2 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Orthopox_F8 PF05886.11 RUS74608.1 - 0.04 14.0 0.0 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus F8 protein DUF4816 PF16086.5 RUS74608.1 - 0.2 11.6 22.4 1.8e+04 -11.1 22.4 4.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) zf-C4 PF00105.18 RUS74610.1 - 8.9e-24 83.7 8.7 1.2e-23 83.3 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Dickkopf_N PF04706.12 RUS74611.1 - 8.3 7.0 8.9 11 6.6 0.1 2.9 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region CIAPIN1 PF05093.13 RUS74612.1 - 1.4 9.5 5.5 0.5 10.9 0.9 2.6 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Rhomboid PF01694.22 RUS74613.1 - 2.9e-25 89.0 6.8 4.9e-25 88.3 6.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 RUS74613.1 - 0.00039 20.9 0.6 0.00039 20.9 0.6 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF4573 PF15140.6 RUS74614.1 - 2.2e-05 24.3 23.8 1.3 8.8 22.9 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Cementoin PF10511.9 RUS74615.1 - 0.0035 17.5 73.2 5.9 7.3 3.5 9.3 1 1 18 19 19 19 19 Trappin protein transglutaminase binding domain 7tm_1 PF00001.21 RUS74616.1 - 5.2e-25 88.3 0.0 7.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ldl_recept_a PF00057.18 RUS74616.1 - 5.2e-14 52.2 42.8 0.0014 18.8 1.3 6.9 5 1 1 6 6 6 6 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 RUS74616.1 - 1.1e-09 37.9 11.8 2e-05 24.3 5.1 3.5 3 0 0 3 3 3 3 Leucine rich repeat Lectin_C PF00059.21 RUS74616.1 - 9.4e-07 29.5 0.0 3.6e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Lectin C-type domain LRR_4 PF12799.7 RUS74616.1 - 5.3e-06 26.7 4.7 0.00083 19.7 0.2 3.6 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Git3 PF11710.8 RUS74616.1 - 0.00011 22.1 1.5 0.00018 21.4 1.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 RUS74616.1 - 0.0075 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS74616.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DSBA PF01323.20 RUS74617.1 - 1.1e-26 93.9 0.0 1.3e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 RUS74617.1 - 1.8e-05 25.0 0.2 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 RUS74617.1 - 0.00023 21.1 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain DNA_photolyase PF00875.18 RUS74619.1 - 6.3e-28 97.8 0.0 1.5e-27 96.6 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase DDRGK PF09756.9 RUS74619.1 - 0.038 13.6 19.0 0.42 10.2 21.2 1.5 2 0 0 2 2 2 0 DDRGK domain SLC12 PF03522.15 RUS74619.1 - 3.4 6.6 10.7 4.8 6.1 10.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 IF4E PF01652.18 RUS74620.1 - 2.9e-54 183.2 0.1 3.4e-54 182.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ADP_ribosyl_GH PF03747.14 RUS74621.1 - 4.3e-43 148.1 0.2 6.2e-43 147.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pea-VEAacid PF08111.11 RUS74621.1 - 0.085 13.2 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 Pea-VEAacid family zf-C3HC4_3 PF13920.6 RUS74622.1 - 2.1e-13 49.9 13.9 3e-13 49.4 13.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.30 RUS74622.1 - 7.3e-10 39.1 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS74622.1 - 1.5e-08 34.6 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 RUS74622.1 - 0.00011 22.0 14.5 0.00019 21.2 14.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS74622.1 - 0.002 18.4 16.4 0.0031 17.8 16.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS74622.1 - 0.0057 16.4 1.4 0.0057 16.4 1.4 2.0 2 0 0 2 2 2 1 RING-like zinc finger IGR PF09597.10 RUS74622.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif Gastrin PF00918.17 RUS74622.1 - 0.05 14.6 1.6 0.05 14.6 1.6 1.6 2 0 0 2 2 2 0 Gastrin/cholecystokinin family SAM_4 PF18017.1 RUS74622.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-RING_5 PF14634.6 RUS74622.1 - 0.13 12.3 14.2 0.22 11.5 14.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS74622.1 - 1.5 8.9 11.5 1.4 9.0 9.7 1.8 1 1 1 2 2 2 0 RING-type zinc-finger Cg6151-P PF10233.9 RUS74624.1 - 3.4e-23 82.1 8.0 4.3e-23 81.8 8.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 RUS74624.1 - 0.00011 22.3 1.6 0.00015 21.9 1.6 1.2 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 RUS74624.1 - 0.00033 20.4 1.5 0.00041 20.1 1.5 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 DUF4191 PF13829.6 RUS74624.1 - 0.032 13.6 1.8 1.7 7.9 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Caveolin PF01146.17 RUS74624.1 - 0.25 11.3 2.6 0.31 11.0 2.3 1.4 1 1 0 1 1 1 0 Caveolin Cytochrom_B558a PF05038.13 RUS74624.1 - 0.47 10.0 3.1 1.6 8.3 3.1 1.8 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit TMEM238 PF15125.6 RUS74624.1 - 3.7 7.8 8.9 0.66 10.2 5.2 1.8 2 0 0 2 2 2 0 TMEM238 protein family Abhydrolase_3 PF07859.13 RUS74626.1 - 5.7e-05 23.1 0.0 7.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RUS74626.1 - 0.15 10.9 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family TPMT PF05724.11 RUS74627.1 - 7e-23 81.4 0.0 1.3e-22 80.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 RUS74627.1 - 1.3e-06 29.0 0.0 1.3e-05 25.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS74627.1 - 2e-06 28.3 0.0 6e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS74627.1 - 0.018 15.8 0.0 0.043 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 RUS74627.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF993 PF06187.11 RUS74627.1 - 0.15 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF993) TPMT PF05724.11 RUS74628.1 - 7.1e-16 58.5 0.0 2.7e-15 56.6 0.0 1.8 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 RUS74628.1 - 5e-06 27.2 0.0 9.7e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS74628.1 - 4.5e-05 24.1 0.0 0.00032 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS74628.1 - 0.0004 21.0 0.0 0.0013 19.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RUS74628.1 - 0.09 12.1 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 RUS74628.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain L51_S25_CI-B8 PF05047.16 RUS74629.1 - 1.4e-13 50.5 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Raftlin PF15250.6 RUS74630.1 - 9.1e-07 28.0 0.1 1.1e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Raftlin DUF4177 PF13783.6 RUS74630.1 - 6.3e-05 23.2 0.0 1.4 9.3 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4177) DUF5118 PF17162.4 RUS74630.1 - 0.044 13.6 0.0 8.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5118) DLL_N PF12413.8 RUS74630.1 - 0.44 11.8 7.1 1.5 10.1 2.5 2.6 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal PLAT PF01477.23 RUS74631.1 - 1.8e-42 144.6 1.0 2.2e-20 73.4 0.0 3.1 3 0 0 3 3 3 3 PLAT/LH2 domain AA_permease_2 PF13520.6 RUS74632.1 - 0.016 14.1 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease DUF4576 PF15144.6 RUS74632.1 - 0.098 12.5 1.9 0.18 11.7 1.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) DUF3742 PF12553.8 RUS74632.1 - 0.26 11.4 1.9 0.43 10.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) CENP-B_dimeris PF09026.10 RUS74632.1 - 0.28 11.6 7.6 0.4 11.1 7.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RUS74632.1 - 8.8 6.0 10.9 11 5.6 10.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_C12 PF01088.21 RUS74634.1 - 1.9e-58 197.7 0.0 2.1e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UDPG_MGDP_dh_C PF03720.15 RUS74635.1 - 2.6e-35 121.0 0.0 7.4e-35 119.5 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 RUS74635.1 - 7.6e-35 120.2 1.0 2.6e-34 118.4 1.0 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 RUS74635.1 - 3.8e-32 110.3 0.0 9e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Baculo_ME53 PF06061.11 RUS74638.1 - 0.00036 19.9 2.6 0.97 8.6 0.1 3.0 1 1 2 3 3 3 3 Baculoviridae ME53 Fibrinogen_BP PF08017.11 RUS74638.1 - 0.0042 15.6 11.0 0.0044 15.5 11.0 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein Cornifin PF02389.15 RUS74638.1 - 0.0086 16.3 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 Cornifin (SPRR) family vWF_A PF12450.8 RUS74638.1 - 0.26 11.3 8.9 23 5.0 0.2 3.6 1 1 4 5 5 5 0 von Willebrand factor 7tm_1 PF00001.21 RUS74639.1 - 9.9e-08 31.6 0.0 3.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) CDP-OH_P_transf PF01066.21 RUS74641.1 - 3.8e-12 46.8 0.6 3.8e-12 46.8 0.6 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDE PF12483.8 RUS74644.1 - 5.5e-18 64.9 0.0 8.6e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 RUS74644.1 - 4e-13 49.0 7.9 5.8e-13 48.5 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS74644.1 - 8.1e-07 28.8 8.3 1.3e-06 28.2 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS74644.1 - 3.7e-06 27.2 9.1 5.9e-06 26.5 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS74644.1 - 8.9e-05 22.4 8.4 0.00014 21.7 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS74644.1 - 0.0055 16.6 9.5 0.0088 15.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS74644.1 - 0.21 11.5 9.7 0.34 10.8 9.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4229 PF14012.6 RUS74644.1 - 0.25 11.5 2.7 3.1 8.0 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) SVIP PF15811.5 RUS74644.1 - 0.49 10.9 5.0 1.2 9.7 5.0 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Vpu PF00558.19 RUS74644.1 - 0.82 9.5 3.0 0.4 10.5 0.5 1.8 2 0 0 2 2 2 0 Vpu protein zf-C3HC4_4 PF15227.6 RUS74644.1 - 2.3 8.5 5.4 10 6.4 5.6 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Phosphonate-bd PF12974.7 RUS74645.1 - 1e-26 94.1 0.0 1.1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 RUS74645.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ubiquitin PF00240.23 RUS74646.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Na_sulph_symp PF00939.19 RUS74647.1 - 1.2e-14 54.3 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS74647.1 - 1.2e-06 28.0 0.1 1.3e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Citrate transporter NhaB PF06450.12 RUS74647.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) DUF1646 PF07854.12 RUS74647.1 - 0.041 13.3 0.7 0.05 13.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1646) FtsX PF02687.21 RUS74647.1 - 0.083 13.4 6.6 0.11 13.0 6.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family RRM_1 PF00076.22 RUS74648.1 - 4.7e-17 61.6 0.0 9.4e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS74648.1 - 0.0044 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 RUS74649.1 - 5.3e-29 99.9 16.0 9e-06 26.3 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS74649.1 - 4e-17 62.3 4.2 5e-05 23.5 0.2 4.9 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS74649.1 - 8.6e-08 31.5 0.2 9.7e-05 21.5 0.1 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 RUS74649.1 - 0.052 13.6 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 RUS74649.1 - 0.12 12.4 0.2 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_transf_8 PF01501.20 RUS74650.1 - 4.2e-23 82.2 0.0 9e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RUS74650.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DcpS_C PF11969.8 RUS74651.1 - 8.5e-32 110.0 2.4 1.3e-31 109.4 2.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RUS74651.1 - 1.7e-15 57.5 1.3 2.8e-15 56.8 1.3 1.3 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 RUS74651.1 - 0.00024 21.5 0.6 0.0032 17.9 0.4 2.6 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 RUS74651.1 - 0.00081 19.7 1.1 0.00081 19.7 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS74651.1 - 0.0011 19.0 0.3 0.0011 19.0 0.3 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS74651.1 - 0.005 17.6 0.8 0.005 17.6 0.8 2.7 2 1 1 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 RUS74651.1 - 0.061 13.7 0.1 0.061 13.7 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS74651.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UPF0449 PF15136.6 RUS74652.1 - 0.021 15.3 0.4 0.046 14.2 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4467 PF14729.6 RUS74652.1 - 0.06 13.7 3.5 0.75 10.2 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Ank_2 PF12796.7 RUS74653.1 - 6.1e-46 154.9 18.6 4.4e-15 56.0 0.1 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74653.1 - 4.2e-39 132.4 20.3 8.2e-09 35.8 0.1 6.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS74653.1 - 2.8e-35 119.9 12.3 2.2e-09 37.4 0.0 6.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS74653.1 - 2.4e-26 91.0 16.0 4.7e-06 26.8 0.0 9.0 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 RUS74653.1 - 3.5e-25 85.3 11.9 0.014 15.9 0.1 8.4 8 0 0 8 8 8 7 Ankyrin repeat CDC45 PF02724.14 RUS74653.1 - 0.22 9.8 7.2 0.32 9.2 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF724 PF05266.14 RUS74653.1 - 6.1 6.6 8.0 1.3 8.8 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) OAR PF03826.17 RUS74654.1 - 1.4e-07 31.1 0.6 3.3e-07 29.9 0.6 1.7 1 0 0 1 1 1 1 OAR domain DUF4699 PF15770.5 RUS74654.1 - 7.8 6.2 8.8 2.9 7.6 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4699) zf-HIT PF04438.16 RUS74655.1 - 1.1e-10 41.2 11.5 1.9e-10 40.4 11.5 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2870 PF11069.8 RUS74655.1 - 0.074 13.4 1.7 0.12 12.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF3552 PF12072.8 RUS74656.1 - 0.038 13.4 0.8 0.059 12.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3671 PF12420.8 RUS74656.1 - 1.5 8.9 8.5 0.27 11.3 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function WW PF00397.26 RUS74657.1 - 4.4e-18 65.1 1.3 3.4e-08 33.4 0.2 2.4 2 0 0 2 2 2 2 WW domain FAM181 PF15238.6 RUS74657.1 - 1.2e-05 25.3 1.1 1.2e-05 25.3 1.1 2.6 2 1 0 2 2 2 1 FAM181 TFIIA PF03153.13 RUS74657.1 - 0.0039 17.3 23.7 0.0059 16.7 23.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 RUS74658.1 - 6.1e-54 183.2 0.0 4.2e-30 104.8 0.0 2.3 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RUS74658.1 - 2.2e-17 63.4 0.0 4.2e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 RUS74658.1 - 1.2e-05 25.6 0.2 2.7e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Kinesin-associated GCN5L1 PF06320.13 RUS74658.1 - 0.029 14.5 1.6 30 4.8 0.0 3.3 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) ANT PF03374.14 RUS74658.1 - 0.064 13.6 5.0 5.9 7.3 4.7 2.7 1 1 0 1 1 1 0 Phage antirepressor protein KilAC domain DUF3565 PF12088.8 RUS74658.1 - 1.1 9.3 3.1 2.8e+02 1.5 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3565) Importin_rep PF18773.1 RUS74659.1 - 2.8e-07 30.1 28.5 10 5.9 0.1 8.2 1 1 7 8 8 8 8 Importin 13 repeat Ax_dynein_light PF10211.9 RUS74659.1 - 4.2e-05 23.6 7.2 3.8 7.4 0.0 5.4 1 1 6 7 7 7 1 Axonemal dynein light chain TFIID_20kDa PF03847.13 RUS74659.1 - 0.00026 21.4 10.8 49 4.5 0.0 6.7 1 1 7 8 8 8 0 Transcription initiation factor TFIID subunit A HC2 PF07382.11 RUS74659.1 - 0.00083 19.5 0.0 0.022 14.9 0.0 2.1 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF348 PF03990.14 RUS74659.1 - 0.0046 16.7 12.8 1.5e+02 2.3 0.0 7.6 1 1 7 8 8 8 0 G5-linked-Ubiquitin-like domain CENP-T_C PF15511.6 RUS74659.1 - 0.005 16.9 10.4 22 5.2 0.3 4.5 1 1 5 6 6 6 0 Centromere kinetochore component CENP-T histone fold Baculo_p33 PF05214.12 RUS74659.1 - 0.036 13.8 4.5 5.3 6.7 1.2 3.0 1 1 3 4 4 4 0 Baculovirus P33 Peptidase_C7 PF01830.18 RUS74659.1 - 0.08 12.4 3.5 55 3.1 0.1 4.0 1 1 5 6 6 6 0 Peptidase C7 family REV1_C PF16727.5 RUS74659.1 - 0.43 11.0 8.2 31 5.1 1.3 3.7 1 1 1 2 2 2 0 DNA repair protein REV1 C-terminal domain Headcase PF16002.5 RUS74660.1 - 2.7e-74 248.9 0.9 4.6e-74 248.2 0.9 1.3 1 0 0 1 1 1 1 Headcase protein HECA PF15353.6 RUS74660.1 - 2.7e-45 152.8 7.1 5.9e-45 151.7 7.1 1.6 1 0 0 1 1 1 1 Headcase protein family homologue SRP-alpha_N PF04086.13 RUS74660.1 - 0.35 10.8 9.0 0.63 9.9 9.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Red1 PF07964.11 RUS74660.1 - 1.8 6.7 10.1 2.4 6.3 10.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Taxilin PF09728.9 RUS74661.1 - 1.2e-81 274.3 59.9 1.2e-81 274.3 59.9 2.1 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF3584 PF12128.8 RUS74661.1 - 1.7 6.0 54.5 0.12 9.9 46.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4064 PF13273.6 RUS74662.1 - 4.5e-06 26.9 25.7 1.8e-05 25.0 10.9 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) CD20 PF04103.15 RUS74662.1 - 2.6e-05 24.4 14.2 5.7e-05 23.3 14.2 1.6 1 1 0 1 1 1 1 CD20-like family DUF4834 PF16118.5 RUS74662.1 - 0.0045 17.9 0.4 3.4 8.7 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 RUS74662.1 - 0.0075 17.1 0.2 2.5 9.1 0.0 3.4 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 RUS74662.1 - 0.012 14.5 12.1 4.4 6.0 12.1 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 RUS74662.1 - 0.047 14.2 1.8 0.047 14.2 1.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Phage_holin_3_6 PF07332.11 RUS74662.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.9 1 1 1 2 2 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3328 PF11807.8 RUS74662.1 - 0.15 11.9 0.4 0.95 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) PalH PF08733.10 RUS74662.1 - 0.25 10.3 12.4 0.083 11.9 2.0 2.2 1 1 1 2 2 2 0 PalH/RIM21 SpecificRecomb PF10136.9 RUS74662.1 - 0.83 7.9 6.1 0.25 9.6 0.7 2.0 2 0 0 2 2 2 0 Site-specific recombinase YlaC PF10777.9 RUS74662.1 - 1.2 9.0 5.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC SLC3A2_N PF16028.5 RUS74662.1 - 1.5 8.5 5.5 0.5 10.0 1.6 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF1516 PF07457.11 RUS74662.1 - 2.3 8.5 15.3 0.66 10.2 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) DUF5527 PF17665.1 RUS74662.1 - 6.2 6.3 6.5 1.4 8.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5527) CD20 PF04103.15 RUS74665.1 - 0.00083 19.5 7.8 0.0015 18.6 7.8 1.4 1 1 0 1 1 1 1 CD20-like family DUF2142 PF09913.9 RUS74665.1 - 0.0021 17.0 0.2 0.0026 16.7 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) Phage_holin_3_6 PF07332.11 RUS74665.1 - 0.0026 17.8 3.4 0.039 14.0 0.4 2.1 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF1218 PF06749.12 RUS74665.1 - 0.0076 16.7 8.5 0.19 12.3 4.8 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1218) DUF2207 PF09972.9 RUS74665.1 - 0.016 14.0 1.4 0.018 13.8 1.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SLC3A2_N PF16028.5 RUS74665.1 - 0.019 14.5 0.7 0.019 14.5 0.7 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus MpPF26 PF07666.11 RUS74665.1 - 0.029 14.5 6.0 0.14 12.3 0.6 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 EphA2_TM PF14575.6 RUS74665.1 - 0.17 12.8 0.7 15 6.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PRA1 PF03208.19 RUS74665.1 - 0.25 10.9 3.9 0.37 10.4 3.9 1.3 1 0 0 1 1 1 0 PRA1 family protein TMEM240 PF15207.6 RUS74665.1 - 0.41 10.3 3.7 0.16 11.6 0.3 1.9 1 1 1 2 2 2 0 TMEM240 family DUF3742 PF12553.8 RUS74665.1 - 0.92 9.6 2.1 28 4.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) HemY_N PF07219.13 RUS74665.1 - 1.3 9.3 4.0 21 5.4 0.7 2.1 2 0 0 2 2 2 0 HemY protein N-terminus Ninjurin PF04923.12 RUS74665.1 - 1.3 8.9 6.6 1.6 8.7 1.2 2.2 1 1 1 2 2 2 0 Ninjurin DUF3487 PF11990.8 RUS74665.1 - 1.8 8.5 6.0 8.7 6.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) YlaC PF10777.9 RUS74665.1 - 2.2 8.1 5.3 0.71 9.7 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF973 PF06157.11 RUS74665.1 - 2.6 7.0 9.4 6.3 5.7 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF4133 PF13571.6 RUS74665.1 - 6.8 7.1 9.2 8.9 6.7 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) SdpI PF13630.6 RUS74665.1 - 9.8 6.4 14.2 5.1 7.3 1.0 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family zf-C2H2 PF00096.26 RUS74667.1 - 0.0022 18.4 1.4 0.0052 17.2 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type HTH_32 PF13565.6 RUS74667.1 - 0.0025 18.4 0.0 0.01 16.5 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 RUS74667.1 - 0.0042 17.3 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS74667.1 - 0.015 15.3 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) zf-C2H2_4 PF13894.6 RUS74667.1 - 0.017 15.9 0.9 0.061 14.2 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger HTH_48 PF17906.1 RUS74667.1 - 0.033 14.3 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase HTH_24 PF13412.6 RUS74667.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 RUS74667.1 - 0.07 13.6 0.1 0.2 12.1 0.1 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PCI PF01399.27 RUS74667.1 - 0.076 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 PCI domain HTH_23 PF13384.6 RUS74667.1 - 1.2 9.0 4.2 27 4.7 0.0 3.6 4 0 0 4 4 4 0 Homeodomain-like domain Peptidase_M41 PF01434.18 RUS74668.1 - 2.5e-62 210.1 0.0 4.3e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RUS74668.1 - 1.3e-40 138.9 0.0 3.7e-40 137.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS74668.1 - 5.1e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RUS74668.1 - 3.5e-05 23.8 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS74668.1 - 0.00015 22.2 0.2 0.0017 18.8 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS74668.1 - 0.0003 21.1 0.3 0.029 14.6 0.0 3.4 2 2 0 3 3 3 1 AAA domain AAA_2 PF07724.14 RUS74668.1 - 0.00086 19.5 0.0 0.0036 17.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RUS74668.1 - 0.0025 17.6 0.1 0.016 14.9 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RUS74668.1 - 0.0033 17.2 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 RUS74668.1 - 0.0037 17.5 0.1 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 RUS74668.1 - 0.0064 16.9 0.1 0.022 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 RUS74668.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 RUS74668.1 - 0.024 14.0 0.2 0.067 12.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RUS74668.1 - 0.025 15.1 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS74668.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 1 0 NACHT domain CPT PF07931.12 RUS74668.1 - 0.062 13.1 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Peptidase_M50B PF13398.6 RUS74668.1 - 0.099 12.3 0.2 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase M50B-like Exo_endo_phos_2 PF14529.6 RUS74669.1 - 0.0021 17.9 0.1 0.0062 16.4 0.1 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase GP46 PF07409.12 RUS74669.1 - 0.012 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Phage protein GP46 RT_RNaseH PF17917.1 RUS74671.1 - 2.6e-15 56.6 0.0 6.2e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RUS74671.1 - 3.8e-13 49.3 0.0 9.9e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 RUS74671.1 - 6.6e-12 45.3 0.0 3.1e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS74671.1 - 6e-11 42.6 0.0 1.8e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RUS74671.1 - 1e-10 41.5 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 RUS74671.1 - 0.011 15.8 10.0 0.11 12.6 1.5 2.8 2 0 0 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.6 RUS74672.1 - 4.6e-10 39.4 0.0 8.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS74672.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 RUS74672.1 - 1.4e-07 31.2 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RUS74673.1 - 1.8e-17 63.4 23.1 0.00025 21.8 0.2 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 RUS74673.1 - 5.1e-08 32.6 6.0 2.9e-07 30.2 6.0 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS74673.1 - 5.1e-06 26.4 8.7 5.1e-06 26.4 8.7 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS74673.1 - 1.6e-05 24.6 9.7 5.3e-05 23.0 8.3 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS74673.1 - 1.7e-05 24.8 7.9 9.9e-05 22.4 7.9 2.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 RUS74673.1 - 0.00023 21.8 13.0 0.00023 21.8 13.0 2.4 2 0 0 2 2 1 1 TRAF-type zinc finger UPF0242 PF06785.11 RUS74673.1 - 0.00027 21.1 4.6 0.00045 20.4 4.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus zf-RING_2 PF13639.6 RUS74673.1 - 0.0011 19.2 5.4 0.0011 19.2 5.4 3.1 3 1 0 3 3 1 1 Ring finger domain PspA_IM30 PF04012.12 RUS74673.1 - 0.0016 18.1 1.6 0.0023 17.5 1.6 1.2 1 0 0 1 1 1 1 PspA/IM30 family PI3K_P85_iSH2 PF16454.5 RUS74673.1 - 0.0028 17.3 6.3 0.0044 16.6 6.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF16 PF01519.16 RUS74673.1 - 0.0043 17.5 4.8 0.0079 16.7 4.8 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 Phage_HK97_TLTM PF06120.11 RUS74673.1 - 0.011 15.0 0.3 0.017 14.3 0.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein zf-RING_5 PF14634.6 RUS74673.1 - 0.018 15.0 10.0 0.018 15.0 10.0 3.0 3 0 0 3 3 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 RUS74673.1 - 0.019 15.1 5.0 0.019 15.1 5.0 3.3 1 1 2 3 3 2 0 zinc RING finger of MSL2 ANAPC4_WD40 PF12894.7 RUS74673.1 - 0.023 15.0 1.4 0.98 9.8 0.0 3.9 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3H2C3 PF17122.5 RUS74673.1 - 0.027 14.5 5.8 0.075 13.1 5.8 1.8 1 0 0 1 1 1 0 Zinc-finger Allexi_40kDa PF05549.11 RUS74673.1 - 0.029 13.9 1.2 0.046 13.2 1.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMEM192 PF14802.6 RUS74673.1 - 0.043 12.9 6.8 3.9 6.5 7.3 2.6 1 1 1 2 2 2 0 TMEM192 family zf-RING_6 PF14835.6 RUS74673.1 - 0.053 13.4 5.0 0.2 11.5 5.0 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 RUS74673.1 - 0.11 12.3 6.1 0.35 10.7 6.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAS PF13851.6 RUS74673.1 - 0.45 9.8 7.2 0.8 9.0 7.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC106 PF15794.5 RUS74673.1 - 0.59 9.8 11.7 0.042 13.6 6.8 1.5 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 106 DUF3450 PF11932.8 RUS74673.1 - 0.63 9.3 7.6 1 8.6 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 RUS74673.1 - 1.1 9.7 9.3 0.23 11.9 5.8 1.6 2 0 0 2 2 1 0 Cell division protein ZapB DUF745 PF05335.13 RUS74673.1 - 1.2 8.9 3.9 0.55 9.9 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.8 RUS74673.1 - 1.5 8.9 7.2 2.9 7.9 7.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prok-RING_4 PF14447.6 RUS74673.1 - 2.2 8.2 10.5 3.2 7.7 8.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Sina PF03145.16 RUS74673.1 - 2.4 8.0 24.9 2.2 8.2 16.7 3.1 2 1 0 2 2 2 0 Seven in absentia protein family KxDL PF10241.9 RUS74673.1 - 3.7 7.9 9.2 1.3 9.4 6.0 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein SlyX PF04102.12 RUS74673.1 - 8.5 7.1 9.5 21 5.8 5.4 2.3 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 RUS74673.1 - 8.6 6.2 6.6 3.6 7.4 2.4 2.2 1 1 1 2 2 2 0 Septum formation initiator VCBS PF13517.6 RUS74674.1 - 8.8e-08 32.6 6.7 0.0017 18.9 1.5 3.7 2 2 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RUS74674.1 - 0.13 12.4 6.8 9.8 6.4 0.2 3.4 3 0 0 3 3 3 0 FG-GAP repeat Fibrinogen_C PF00147.18 RUS74675.1 - 9.8e-14 51.7 0.1 1.3e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 RUS74676.1 - 1.7e-55 188.2 10.3 2.2e-55 187.9 10.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fibrinogen_C PF00147.18 RUS74677.1 - 6.6e-136 451.2 28.6 4.2e-54 183.7 6.8 3.1 3 0 0 3 3 3 3 Fibrinogen beta and gamma chains, C-terminal globular domain TFIIA PF03153.13 RUS74680.1 - 0.019 15.0 7.2 0.029 14.4 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RUS74680.1 - 0.05 13.2 12.8 0.097 12.3 12.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.9 RUS74680.1 - 0.34 10.9 14.0 0.61 10.1 14.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MAP65_ASE1 PF03999.12 RUS74680.1 - 0.62 8.7 5.0 1.3 7.7 5.0 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Activator_LAG-3 PF11498.8 RUS74680.1 - 0.66 8.9 22.7 1.3 7.9 22.7 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EPL1 PF10513.9 RUS74680.1 - 5 7.5 5.9 1.3 9.3 2.2 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like SspK PF08176.12 RUS74682.1 - 0.22 11.8 3.3 0.24 11.7 0.1 2.5 2 1 0 2 2 2 0 Small acid-soluble spore protein K family Ion_trans PF00520.31 RUS74683.1 - 5.8e-15 55.2 0.3 6.2e-15 55.1 0.3 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS74683.1 - 1.8e-14 53.4 2.5 3e-14 52.7 2.5 1.3 1 0 0 1 1 1 1 Ion channel DUF3185 PF11381.8 RUS74683.1 - 0.024 14.6 1.3 0.046 13.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Nop14 PF04147.12 RUS74684.1 - 0.00027 19.3 25.6 0.00031 19.1 25.6 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS74684.1 - 0.001 17.5 17.7 0.0012 17.2 17.7 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 RUS74684.1 - 0.0017 16.5 42.6 0.0022 16.2 42.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 RUS74684.1 - 0.044 12.2 20.6 0.052 12.0 20.6 1.0 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 RUS74684.1 - 0.13 11.0 6.0 0.14 10.9 6.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS74684.1 - 0.21 11.0 31.5 0.25 10.7 31.5 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 RUS74684.1 - 0.46 10.3 4.6 0.52 10.1 4.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2722 PF10846.8 RUS74684.1 - 0.49 9.3 19.0 0.61 9.0 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) IFT57 PF10498.9 RUS74684.1 - 6.4 5.6 11.1 8.1 5.3 11.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMEM151 PF14857.6 RUS74685.1 - 8.9e-148 492.7 0.1 8.9e-148 492.7 0.1 1.7 2 0 0 2 2 2 1 TMEM151 family TFIIA PF03153.13 RUS74685.1 - 0.041 13.9 15.4 0.065 13.2 15.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RUS74685.1 - 0.88 9.1 19.3 1.4 8.5 19.3 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 RUS74685.1 - 3.8 7.4 8.9 6.9 6.6 8.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) T2SSM_b PF10741.9 RUS74686.1 - 0.021 14.6 1.6 6.2 6.7 0.1 2.9 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M subtype b Big_1 PF02369.16 RUS74686.1 - 2.2 8.4 9.3 14 5.8 0.6 3.5 1 1 3 4 4 4 0 Bacterial Ig-like domain (group 1) CEL_III_C PF18054.1 RUS74686.1 - 5 7.2 6.9 38 4.3 6.9 2.3 1 1 0 1 1 1 0 CEL-III C-terminal Il2rg PF15874.5 RUS74688.1 - 3.4e-22 78.5 0.0 4.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain ASC PF00858.24 RUS74690.1 - 2.5e-09 36.6 0.7 3.5e-09 36.1 0.7 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS74691.1 - 6.2e-22 78.2 6.5 6.8e-16 58.3 2.9 3.3 2 1 0 2 2 2 2 Amiloride-sensitive sodium channel MTBP_mid PF14919.6 RUS74691.1 - 0.08 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding Rap_GAP PF02145.15 RUS74693.1 - 4.7e-44 150.2 0.0 1.1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Spore_YpjB PF09577.10 RUS74694.1 - 0.0038 17.1 0.1 0.0054 16.6 0.1 1.1 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) Prominin PF05478.11 RUS74694.1 - 0.089 10.7 0.1 0.088 10.8 0.1 1.2 1 0 0 1 1 1 0 Prominin GTP_cyclohydroI PF01227.22 RUS74695.1 - 4.9e-55 185.7 0.3 5.5e-55 185.6 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RUS74695.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.6 RUS74695.1 - 0.078 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tcp10_C PF07202.13 RUS74698.1 - 0.022 14.7 0.0 6.3 6.7 0.0 2.8 1 1 1 2 2 2 0 T-complex protein 10 C-terminus Methyltransf_30 PF05430.11 RUS74698.1 - 0.56 10.1 7.2 5.6 6.9 0.3 3.2 1 1 3 4 4 4 0 S-adenosyl-L-methionine-dependent methyltransferase Hen1_Lam_C PF18441.1 RUS74698.1 - 6.7 6.6 14.1 12 5.8 1.0 3.4 1 1 3 4 4 4 0 Hen1 La-motif C-terminal domain Tctex-1 PF03645.13 RUS74700.1 - 2.2e-21 76.0 0.6 2.9e-21 75.6 0.6 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF2895 PF11444.8 RUS74700.1 - 0.033 13.6 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) ERAP1_C PF11838.8 RUS74701.1 - 1.5e-91 307.2 0.0 9.2e-91 304.7 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 RUS74701.1 - 9.6e-87 290.1 0.4 1.6e-46 158.6 0.2 2.4 2 0 0 2 2 2 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RUS74701.1 - 7e-53 179.6 0.0 1.3e-52 178.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Arylesterase PF01731.20 RUS74703.1 - 4.6e-24 84.4 0.1 6.2e-12 45.5 0.0 2.9 3 0 0 3 3 3 2 Arylesterase SGL PF08450.12 RUS74703.1 - 0.00012 21.7 0.0 0.027 14.1 0.0 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Trehalose_recp PF06151.13 RUS74703.1 - 0.089 11.4 0.0 5 5.6 0.0 2.1 1 1 1 2 2 2 0 Trehalose receptor zf-RVT PF13966.6 RUS74704.1 - 0.011 16.4 0.0 0.034 14.8 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Hjc PF01870.18 RUS74704.1 - 0.2 11.6 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) RVT_1 PF00078.27 RUS74705.1 - 0.003 17.1 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 RUS74705.1 - 0.015 16.0 0.0 0.044 14.5 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF2039 PF10217.9 RUS74708.1 - 0.02 15.2 2.6 0.044 14.1 2.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Fer4_8 PF13183.6 RUS74708.1 - 8.4 6.9 12.8 16 6.0 9.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain IBB PF01749.20 RUS74709.1 - 0.018 15.5 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 0 Importin beta binding domain Lant_dehydr_N PF04738.13 RUS74710.1 - 0.07 11.2 0.0 0.075 11.1 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus CBM_14 PF01607.24 RUS74711.1 - 2.1e-05 24.6 19.4 3e-05 24.1 3.1 2.4 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain SMBP PF16785.5 RUS74712.1 - 0.076 13.2 0.1 0.4 10.9 0.1 2.4 1 1 0 1 1 1 0 Small metal-binding protein Perilipin PF03036.16 RUS74712.1 - 0.35 9.8 7.2 2.5 7.0 1.1 2.1 1 1 1 2 2 2 0 Perilipin family Herpes_BLLF1 PF05109.13 RUS74712.1 - 4.9 5.0 17.6 0.18 9.7 9.4 1.7 1 1 1 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) COesterase PF00135.28 RUS74714.1 - 4.4e-117 392.1 0.0 5.1e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS74714.1 - 1.2e-08 35.1 0.1 3.1e-08 33.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioredoxin_6 PF13848.6 RUS74715.1 - 2.7e-16 60.0 3.5 9.9e-12 45.1 0.0 5.5 5 1 1 6 6 6 2 Thioredoxin-like domain Thioredoxin PF00085.20 RUS74715.1 - 6.4e-05 22.9 0.1 0.0012 18.8 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin T6_Ig_like PF18002.1 RUS74715.1 - 0.087 12.7 0.2 14 5.5 0.1 2.4 2 0 0 2 2 2 0 T6 antigen Ig like domain Somatomedin_B PF01033.17 RUS74716.1 - 0.0012 19.2 17.1 0.007 16.7 17.1 2.2 1 1 0 1 1 1 1 Somatomedin B domain ADAM17_MPD PF16698.5 RUS74717.1 - 7.5 7.0 13.6 4.8 7.6 4.9 2.8 2 1 1 3 3 3 0 Membrane-proximal domain, switch, for ADAM17 HBS1_N PF08938.10 RUS74718.1 - 0.00063 20.0 0.3 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 HBS1 N-terminus RIIa PF02197.17 RUS74718.1 - 0.0077 15.9 0.5 0.04 13.6 0.0 2.4 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit HORMA PF02301.18 RUS74719.1 - 2.6e-51 174.2 0.0 6.6e-51 172.9 0.0 1.7 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 RUS74719.1 - 4.7e-05 23.2 12.0 0.0001 22.1 12.0 1.6 1 0 0 1 1 1 1 PHD-finger MarR PF01047.22 RUS74719.1 - 0.00029 20.7 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 RUS74719.1 - 0.00037 20.3 0.1 0.00071 19.4 0.1 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 RUS74719.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 RUS74719.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 RUS74719.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 RUS74719.1 - 0.066 13.0 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 RUS74719.1 - 0.066 12.8 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FtsK_gamma PF09397.10 RUS74719.1 - 0.081 12.7 0.2 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Ftsk gamma domain PHD_2 PF13831.6 RUS74719.1 - 0.09 12.4 3.0 0.17 11.5 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Ribosomal_S25 PF03297.15 RUS74719.1 - 0.57 10.4 0.0 0.57 10.4 0.0 3.0 2 1 0 2 2 2 0 S25 ribosomal protein Vinculin PF01044.19 RUS74720.1 - 4.9e-256 852.6 16.2 2.8e-195 651.5 9.7 2.2 1 1 1 2 2 2 2 Vinculin family IF-2B PF01008.17 RUS74720.1 - 0.04 13.1 1.5 0.35 10.1 0.4 2.8 2 0 0 2 2 2 0 Initiation factor 2 subunit family CD20 PF04103.15 RUS74721.1 - 0.021 14.9 1.8 0.021 14.9 1.8 2.7 1 1 1 2 2 2 0 CD20-like family SH2 PF00017.24 RUS74722.1 - 7.2e-14 51.7 0.0 1.8e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain PID PF00640.23 RUS74722.1 - 0.19 11.8 0.1 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) DUF2254 PF10011.9 RUS74722.1 - 1.1 8.1 4.0 2.3 7.0 4.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Man-6-P_recep PF02157.15 RUS74724.1 - 1.9e-80 269.6 0.1 2.4e-80 269.3 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 RUS74724.1 - 7.4e-12 45.7 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 RUS74724.1 - 0.07 13.2 0.3 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat CDC45 PF02724.14 RUS74725.1 - 2.7e-08 32.6 10.8 3e-08 32.5 10.8 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 RUS74725.1 - 2e-07 31.4 12.2 2.8e-07 30.9 12.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein RRN3 PF05327.11 RUS74725.1 - 0.0002 20.1 17.5 0.00021 20.0 17.5 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 RUS74725.1 - 0.002 16.7 17.0 0.0026 16.3 17.0 1.1 1 0 0 1 1 1 1 Mpp10 protein DNA_pol_phi PF04931.13 RUS74725.1 - 2.1 6.4 51.2 2.9 5.9 51.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RUS74726.1 - 1e-05 25.0 12.1 1e-05 25.0 12.1 2.3 2 0 0 2 2 2 1 NOA36 protein BUD22 PF09073.10 RUS74726.1 - 0.00019 20.9 26.8 0.00028 20.3 26.8 1.2 1 0 0 1 1 1 1 BUD22 DUF1115 PF06544.12 RUS74726.1 - 0.0011 19.1 4.3 0.13 12.4 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) Caskin1-CID PF16600.5 RUS74726.1 - 0.072 13.7 0.7 22 5.7 0.0 2.7 3 0 0 3 3 3 0 Caskin1 CASK-interaction domain Slu7 PF11708.8 RUS74726.1 - 1.1 8.9 26.0 2.1 8.0 8.8 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DNA_pol_phi PF04931.13 RUS74726.1 - 1.5 6.8 74.5 0.82 7.7 32.4 2.0 2 0 0 2 2 2 0 DNA polymerase phi Vfa1 PF08432.10 RUS74726.1 - 1.9 8.8 16.6 2.2 8.6 4.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Afi1 PF07792.12 RUS74726.1 - 6 7.4 25.7 4 7.9 8.3 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 RUS74726.1 - 7.8 4.6 50.4 1.7 6.7 20.7 2.0 2 0 0 2 2 2 0 Nop14-like family 7tm_1 PF00001.21 RUS74727.1 - 2.8e-72 243.2 16.9 5.9e-72 242.2 16.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS74727.1 - 9.6e-09 35.0 12.6 2.8e-07 30.2 3.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS74727.1 - 1.2e-05 25.2 1.4 1.2e-05 25.2 1.4 2.9 2 1 1 3 3 3 1 Olfactory receptor YajC PF02699.15 RUS74727.1 - 0.42 10.5 3.8 0.3 11.0 1.1 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Borrelia_P83 PF05262.11 RUS74727.1 - 2.9 6.3 8.2 0.081 11.4 0.1 2.2 2 1 1 3 3 3 0 Borrelia P83/100 protein Connexin PF00029.19 RUS74727.1 - 4.4 7.0 7.7 0.91 9.2 0.5 2.8 3 0 0 3 3 3 0 Connexin Asp-B-Hydro_N PF05279.11 RUS74728.1 - 0.22 11.6 8.1 0.28 11.2 8.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2244 PF10003.9 RUS74728.1 - 0.28 10.9 1.8 0.42 10.3 1.8 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF724 PF05266.14 RUS74728.1 - 0.57 10.0 10.2 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NAM-associated PF14303.6 RUS74728.1 - 2.2 9.0 12.7 3.8 8.2 12.6 1.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain FAD_binding_1 PF00667.20 RUS74730.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain INTS5_N PF14837.6 RUS74730.1 - 0.16 11.6 0.1 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus NTPase_1 PF03266.15 RUS74731.1 - 0.04 13.8 0.3 0.22 11.4 0.0 2.3 2 1 0 2 2 2 0 NTPase NB-ARC PF00931.22 RUS74731.1 - 0.049 12.8 0.1 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain GAS PF13851.6 RUS74733.1 - 6.9e-05 22.3 111.7 0.042 13.2 29.3 5.3 1 1 4 5 5 5 5 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 RUS74733.1 - 0.0033 16.4 21.8 0.0033 16.4 21.8 4.1 1 1 3 4 4 4 2 Spc7 kinetochore protein ATG16 PF08614.11 RUS74733.1 - 0.011 15.9 87.4 0.35 11.1 17.9 5.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Syntaxin PF00804.25 RUS74733.1 - 0.013 15.2 7.1 0.013 15.2 7.1 5.6 2 2 4 6 6 6 0 Syntaxin KASH_CCD PF14662.6 RUS74733.1 - 0.87 9.4 108.1 1.2 8.9 18.5 5.3 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 RUS74733.1 - 3.8 7.0 86.4 0.82 9.2 47.2 4.0 1 1 2 3 3 3 0 Intermediate filament protein MAD PF05557.13 RUS74733.1 - 9.1 4.5 101.1 0.75 8.1 50.9 3.0 1 1 2 3 3 3 0 Mitotic checkpoint protein Pkinase PF00069.25 RUS74735.1 - 7.8e-43 146.7 0.6 8.7e-43 146.6 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74735.1 - 6.4e-15 55.1 0.0 8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS74735.1 - 1.1e-08 34.7 0.1 1.4e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS74735.1 - 0.00029 20.5 0.4 0.00035 20.2 0.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RUS74735.1 - 0.0003 19.7 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RUS74735.1 - 0.00035 19.6 0.4 0.00044 19.3 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS74735.1 - 0.0004 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS74735.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3246 PF11596.8 RUS74736.1 - 0.41 10.0 4.2 0.31 10.4 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Sigma70_ner PF04546.13 RUS74736.1 - 3.4 7.5 9.5 2.4 8.0 3.6 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region BIR PF00653.21 RUS74737.1 - 6.5e-16 58.7 1.4 1.1e-15 58.1 1.4 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain FAD_binding_1 PF00667.20 RUS74739.1 - 0.0023 17.5 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Sema PF01403.19 RUS74741.1 - 1e-27 97.1 0.5 1.3e-27 96.7 0.5 1.1 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 RUS74742.1 - 4.2e-198 659.5 3.2 1.4e-197 657.8 3.2 1.7 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 RUS74742.1 - 1.3e-30 105.3 12.1 3e-11 43.2 0.0 4.7 4 0 0 4 4 4 4 IPT/TIG domain TIG_2 PF18020.1 RUS74742.1 - 1.1e-12 48.4 0.1 5.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 TIG domain found in plexin CD34_antigen PF06365.12 RUS74742.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family RIFIN PF02009.16 RUS74742.1 - 0.047 13.6 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Rifin TMEM132D_C PF15706.5 RUS74742.1 - 0.14 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term zf-C2H2_jaz PF12171.8 RUS74743.1 - 0.0013 19.0 4.5 2.6 8.4 0.9 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS74743.1 - 0.062 13.8 20.5 3.9 8.1 3.0 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C3HC PF07967.13 RUS74743.1 - 0.11 12.5 4.4 3.4 7.7 0.7 3.0 2 0 0 2 2 2 0 C3HC zinc finger-like zf-C2H2_6 PF13912.6 RUS74743.1 - 0.11 12.5 6.0 0.59 10.2 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS74743.1 - 0.22 12.4 32.6 1.2 10.1 0.0 6.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-3CxxC_2 PF17180.4 RUS74743.1 - 4.4 8.1 14.5 0.23 12.2 3.8 4.4 3 0 0 3 3 3 0 Zinc-binding domain Xan_ur_permease PF00860.20 RUS74744.1 - 1.3e-71 241.4 27.9 1.7e-65 221.2 17.1 2.3 2 1 1 3 3 3 2 Permease family LRR_6 PF13516.6 RUS74745.1 - 3.4e-21 73.4 7.8 1e-05 25.2 0.0 5.4 5 0 0 5 5 5 5 Leucine Rich repeat LRR_1 PF00560.33 RUS74745.1 - 2.1e-09 36.6 0.1 3.7 8.5 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.7 RUS74745.1 - 0.0018 18.7 5.3 0.13 12.8 1.1 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) GST_C_3 PF14497.6 RUS74747.1 - 2.6e-17 62.8 0.0 4.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS74747.1 - 6.9e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS74747.1 - 4.3e-08 33.3 0.0 7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 RUS74747.1 - 0.051 14.2 0.0 0.084 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS74747.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Defensin_propep PF00879.18 RUS74749.1 - 0.015 15.5 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_propep PF00879.18 RUS74750.1 - 0.016 15.5 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Defensin propeptide Fibrinogen_aC PF12160.8 RUS74752.1 - 0.067 13.0 2.3 1.1 9.1 2.3 3.2 1 0 0 1 1 1 0 Fibrinogen alpha C domain Phycoerythr_ab PF02972.14 RUS74752.1 - 0.096 12.5 0.2 0.37 10.6 0.2 2.0 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain Ank_2 PF12796.7 RUS74753.1 - 5.2e-35 119.9 5.4 1.1e-11 45.1 0.1 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS74753.1 - 5.8e-34 115.7 10.6 9.2e-09 35.4 0.1 7.2 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS74753.1 - 1.7e-26 92.2 9.1 5.2e-08 33.3 0.1 6.0 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS74753.1 - 2e-22 76.8 6.4 0.0016 18.7 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 RUS74753.1 - 3.9e-21 74.5 15.8 0.018 15.5 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat SCAN PF02023.17 RUS74755.1 - 8.5e-15 54.4 0.5 3.4e-13 49.2 0.2 2.8 2 0 0 2 2 2 1 SCAN domain zf-CCHC PF00098.23 RUS74755.1 - 0.00097 19.1 3.0 0.00097 19.1 3.0 2.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS74755.1 - 0.0013 18.5 7.0 0.0013 18.5 7.0 2.4 3 0 0 3 3 3 1 Zinc knuckle Sar8_2 PF03058.14 RUS74755.1 - 0.024 15.1 1.7 0.024 15.1 1.7 2.1 2 1 1 3 3 3 0 Sar8.2 family zf-CCHC_4 PF14392.6 RUS74755.1 - 0.085 12.6 10.1 0.12 12.1 1.5 2.6 2 0 0 2 2 2 0 Zinc knuckle Lectin_C PF00059.21 RUS74756.1 - 0.00098 19.8 0.0 0.0015 19.2 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Glyco_transf_92 PF01697.27 RUS74757.1 - 3.5e-37 128.5 2.4 3e-28 99.2 0.3 3.3 3 0 0 3 3 2 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS74757.1 - 2.1e-06 28.1 0.1 2.1e-06 28.1 0.1 2.8 3 1 0 3 3 2 1 Glycosyl transferase family 2 PAT1 PF09770.9 RUS74757.1 - 0.0025 16.2 58.4 0.0038 15.6 58.4 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC45 PF02724.14 RUS74757.1 - 0.0045 15.4 17.5 0.0064 14.8 17.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SPX PF03105.19 RUS74757.1 - 0.011 15.7 19.6 0.018 15.0 19.6 1.4 1 0 0 1 1 1 0 SPX domain SID-1_RNA_chan PF13965.6 RUS74757.1 - 0.02 13.3 2.5 0.026 13.0 2.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.18 RUS74757.1 - 0.69 8.2 3.3 0.79 8.0 3.3 1.1 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 RUS74757.1 - 0.94 6.5 30.6 1.2 6.1 30.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paf1 PF03985.13 RUS74757.1 - 1.1 8.2 32.7 1.9 7.4 32.7 1.3 1 0 0 1 1 1 0 Paf1 Lin-8 PF03353.15 RUS74757.1 - 1.6 8.2 36.0 2.7 7.5 36.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 RUS74757.1 - 1.8 7.3 20.0 2.5 6.8 20.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PPL5 PF18168.1 RUS74757.1 - 8.8 5.5 20.0 14 4.8 20.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DHFR_1 PF00186.19 RUS74758.1 - 5.3e-19 68.5 0.0 6.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Phospholip_B PF04916.13 RUS74760.1 - 2.7e-56 191.3 0.1 3.3e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B DUF2985 PF11204.8 RUS74762.1 - 0.026 14.7 0.3 0.051 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) PY_rept_46 PF09689.10 RUS74763.1 - 3.2e-07 30.8 12.9 17 6.1 0.2 5.7 1 1 1 2 2 2 1 Plasmodium yoelii repeat (PY_rept_46) Peptidase_M50B PF13398.6 RUS74763.1 - 0.72 9.4 12.1 38 3.8 0.1 4.7 1 1 5 6 6 6 0 Peptidase M50B-like Usp PF00582.26 RUS74764.1 - 5.8e-23 82.0 0.1 7.2e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family PIG-L PF02585.17 RUS74764.1 - 0.02 15.5 0.0 0.029 15.0 0.0 1.3 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase Phage_CRI PF05144.14 RUS74764.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI DUF3456 PF11938.8 RUS74765.1 - 1.1e-07 32.5 6.0 3.2e-05 24.5 0.2 2.6 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP Laminin_EGF PF00053.24 RUS74765.1 - 0.00054 20.0 13.2 0.00054 20.0 13.2 4.3 3 1 1 4 4 4 1 Laminin EGF domain EGF_2 PF07974.13 RUS74765.1 - 0.015 15.7 16.8 0.015 15.7 16.8 4.5 6 1 0 6 6 6 0 EGF-like domain Vpu PF00558.19 RUS74765.1 - 0.11 12.3 0.8 0.2 11.4 0.1 1.8 1 1 1 2 2 2 0 Vpu protein EGF_CA PF07645.15 RUS74766.1 - 6e-13 48.8 41.2 6.1e-07 29.5 11.5 3.2 2 1 1 3 3 3 2 Calcium-binding EGF domain EGF PF00008.27 RUS74766.1 - 5.9e-05 23.3 18.5 0.0077 16.5 6.1 3.1 2 1 0 2 2 2 2 EGF-like domain FXa_inhibition PF14670.6 RUS74766.1 - 0.00045 20.4 32.2 0.002 18.4 6.2 3.7 2 2 1 3 3 3 2 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 RUS74766.1 - 0.0041 17.4 29.5 2.2e+03 -0.9 29.5 2.9 1 1 0 1 1 1 0 Pvs28 EGF domain EGF_3 PF12947.7 RUS74766.1 - 0.046 13.9 7.2 0.046 13.9 7.2 3.2 2 2 1 3 3 3 0 EGF domain PPP4R2 PF09184.11 RUS74768.1 - 1.2e-54 185.9 0.3 1.2e-54 185.9 0.3 3.2 2 1 1 3 3 3 1 PPP4R2 Peptidase_C7 PF01830.18 RUS74769.1 - 7.3e-05 22.3 0.1 11 5.4 0.0 4.0 1 1 3 4 4 4 3 Peptidase C7 family DUF5551 PF17705.1 RUS74769.1 - 0.0009 18.9 0.9 29 4.3 0.0 4.0 4 0 0 4 4 4 2 Family of unknown function (DUF5551) YjbH PF06082.11 RUS74769.1 - 0.0011 17.9 4.0 4.7 5.9 0.1 3.7 1 1 3 4 4 4 3 Exopolysaccharide biosynthesis protein YbjH TRAPPC10 PF12584.8 RUS74769.1 - 0.082 12.6 0.0 47 3.6 0.0 4.1 5 0 0 5 5 5 0 Trafficking protein particle complex subunit 10, TRAPPC10 zf-C4_Topoisom PF01396.19 RUS74769.1 - 0.14 11.9 5.9 90 3.0 0.1 4.3 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Peptidase_S64 PF08192.11 RUS74770.1 - 0.42 9.1 8.8 0.47 8.9 8.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Cu-oxidase_3 PF07732.15 RUS74771.1 - 2.6e-38 130.7 0.0 9.9e-38 128.8 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 RUS74771.1 - 5.1e-20 72.2 0.0 8.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RUS74771.1 - 1e-10 41.5 4.2 2.4e-05 24.1 0.3 4.0 3 1 0 3 3 3 3 Multicopper oxidase Trypsin_2 PF13365.6 RUS74772.1 - 3e-07 31.4 0.1 5.7e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Cu-oxidase_3 PF07732.15 RUS74773.1 - 7.9e-39 132.3 0.8 3.7e-37 127.0 0.0 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RUS74773.1 - 7.2e-35 119.7 0.6 8.7e-30 103.2 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RUS74773.1 - 9.3e-30 103.8 0.3 2.9e-29 102.3 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Abhydrolase_3 PF07859.13 RUS74774.1 - 5.5e-52 176.7 0.0 2.1e-36 125.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RUS74774.1 - 0.0031 16.4 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Astacin PF01400.24 RUS74775.1 - 3e-56 190.1 0.5 5.5e-56 189.2 0.5 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 RUS74775.1 - 9.9e-18 64.4 84.3 5e-08 33.4 10.7 5.4 5 0 0 5 5 5 4 ShK domain-like Peptidase_M10 PF00413.24 RUS74775.1 - 0.0039 17.1 2.1 0.43 10.4 0.6 2.3 1 1 1 2 2 2 2 Matrixin Peptidase_M66 PF10462.9 RUS74775.1 - 0.0055 15.7 0.7 0.011 14.7 0.6 1.6 1 1 0 1 1 1 1 Peptidase M66 MFS_1 PF07690.16 RUS74776.1 - 5.4e-30 104.5 21.7 3.7e-25 88.6 16.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS74776.1 - 4.3e-11 42.7 23.3 4.7e-08 32.7 8.3 2.0 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 RUS74776.1 - 0.035 12.4 7.5 0.74 8.0 1.0 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 RUS74776.1 - 5 6.9 6.3 8.2 6.2 0.7 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 CPT_N PF16484.5 RUS74777.1 - 0.14 12.2 0.3 0.36 10.9 0.3 1.7 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus YabA PF06156.13 RUS74777.1 - 0.4 11.3 0.1 0.4 11.3 0.1 2.5 3 0 0 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 RUS74777.1 - 1.2 9.2 3.7 17 5.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 RUS74777.1 - 2.2 8.5 6.5 0.41 10.9 1.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 RUS74777.1 - 5.7 7.1 6.9 18 5.5 1.2 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RBP_receptor PF14752.6 RUS74778.1 - 2e-61 208.3 5.8 2.3e-61 208.2 5.8 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor Sid-5 PF17204.3 RUS74778.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Sid-5 family C_tripleX PF02363.19 RUS74779.1 - 5 7.6 61.9 90 3.7 0.5 9.2 4 3 1 5 5 5 0 Cysteine rich repeat Glyco_transf_11 PF01531.16 RUS74780.1 - 2.4e-35 122.2 0.0 4.7e-35 121.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 11 Thioredoxin_12 PF18400.1 RUS74780.1 - 0.028 14.3 0.1 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain zf-C2H2 PF00096.26 RUS74782.1 - 3.9e-34 115.2 84.8 1.2e-07 31.7 3.5 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS74782.1 - 1.1e-31 106.8 76.4 0.00042 20.9 2.5 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS74782.1 - 5.1e-30 102.5 86.0 4.9e-08 33.1 3.4 11.1 9 1 2 11 11 11 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS74782.1 - 5.7e-12 45.6 49.1 0.022 15.0 0.3 10.7 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS74782.1 - 2e-07 30.6 60.7 0.043 13.6 0.3 9.9 10 0 0 10 10 10 7 zinc-finger C2H2-type zf-met PF12874.7 RUS74782.1 - 3.7e-07 30.3 45.3 0.015 15.6 1.7 8.8 8 0 0 8 8 8 4 Zinc-finger of C2H2 type GAGA PF09237.11 RUS74782.1 - 9.9e-07 28.5 6.1 0.8 9.6 0.3 5.9 4 1 2 6 6 5 2 GAGA factor zf-Di19 PF05605.12 RUS74782.1 - 0.0012 19.1 51.8 0.5 10.7 3.9 6.9 3 2 5 8 8 8 6 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RUS74782.1 - 0.0041 17.1 2.7 0.0041 17.1 2.7 9.0 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS74782.1 - 0.0055 17.0 40.9 0.015 15.6 7.9 5.5 1 1 3 5 5 5 2 C2H2-type zinc ribbon Baculo_IE-1 PF05290.11 RUS74782.1 - 0.0074 16.2 14.7 2.7 7.9 0.6 5.0 1 1 4 5 5 5 2 Baculovirus immediate-early protein (IE-0) BolA PF01722.18 RUS74782.1 - 0.027 14.7 11.1 0.098 12.9 0.8 4.2 3 1 0 4 4 4 0 BolA-like protein zf-C2HE PF16278.5 RUS74782.1 - 0.069 13.6 1.2 0.069 13.6 1.2 9.1 2 2 4 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger AcylCoA_DH_N PF12418.8 RUS74782.1 - 0.13 12.3 0.1 0.38 10.8 0.1 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal zf-C2H2_2 PF12756.7 RUS74782.1 - 0.98 9.8 55.9 0.76 10.2 0.4 9.2 1 1 8 9 9 9 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 RUS74782.1 - 1.1 9.5 24.4 1.9 8.8 0.0 7.3 8 0 0 8 8 7 0 zinc-ribbon zinc_ribbon_15 PF17032.5 RUS74782.1 - 1.6 9.6 36.9 0.24 12.2 1.1 5.8 2 1 6 8 8 8 0 zinc-ribbon family zf-C2H2_9 PF16293.5 RUS74782.1 - 2.9 7.8 30.7 3.1 7.7 0.1 7.9 5 4 5 10 10 10 0 C2H2 type zinc-finger (1 copy) Lar_restr_allev PF14354.6 RUS74782.1 - 3.3 8.2 23.8 0.16 12.4 1.5 5.1 3 1 1 4 4 4 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 RUS74782.1 - 9.7 6.3 30.1 4.3 7.5 0.0 8.2 9 0 0 9 9 9 0 Sec23/Sec24 zinc finger Transket_pyr PF02779.24 RUS74783.1 - 3.6e-57 192.9 0.0 9e-57 191.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RUS74783.1 - 4.6e-47 159.5 0.0 9.1e-47 158.6 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 RUS74783.1 - 1.2e-41 142.7 0.0 2.3e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component PFOR_II PF17147.4 RUS74783.1 - 0.026 14.8 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Ribonuclease_T2 PF00445.18 RUS74785.1 - 3.5e-51 174.0 3.2 4.3e-51 173.7 3.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Cornifin PF02389.15 RUS74786.1 - 0.0035 17.5 14.9 0.056 13.6 14.9 2.0 1 1 0 1 1 1 1 Cornifin (SPRR) family RTX_C PF08339.10 RUS74786.1 - 0.022 14.9 8.8 47 4.0 8.8 3.1 1 1 0 1 1 1 0 RTX C-terminal domain Stealth_CR2 PF11380.8 RUS74786.1 - 0.39 10.9 9.6 71 3.6 5.3 4.0 1 1 2 3 3 3 0 Stealth protein CR2, conserved region 2 PIG-P PF08510.12 RUS74786.1 - 0.87 9.5 15.5 1.8e+04 -4.9 15.5 3.9 1 1 0 1 1 1 0 PIG-P PheRS_DBD2 PF18554.1 RUS74786.1 - 3.6 7.7 22.9 39 4.4 0.5 7.4 2 2 8 10 10 10 0 PheRS DNA binding domain 2 Herpes_LMP1 PF05297.11 RUS74786.1 - 4 6.5 10.0 2 7.5 4.5 2.0 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Cys_knot PF00007.22 RUS74788.1 - 1.3e-10 41.5 3.4 1.9e-10 41.0 3.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain Acetyltransf_1 PF00583.25 RUS74790.1 - 4.6e-13 49.4 0.0 5.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS74790.1 - 5.6e-09 36.0 0.0 7.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS74790.1 - 1.1e-08 35.3 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS74790.1 - 1.9e-08 34.2 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RUS74790.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_31 PF13847.6 RUS74791.1 - 2.6e-11 43.5 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS74791.1 - 1.9e-10 41.4 0.0 3.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS74791.1 - 2.9e-10 40.7 0.0 5.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS74791.1 - 6e-10 39.7 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS74791.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 RUS74791.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Dimerisation2 PF16864.5 RUS74791.1 - 0.0025 17.8 0.4 0.0075 16.2 0.2 1.9 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_4 PF02390.17 RUS74791.1 - 0.0036 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 RUS74791.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 RUS74791.1 - 0.025 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 RUS74791.1 - 0.053 12.6 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 RUS74791.1 - 0.085 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.14 RUS74791.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 adh_short PF00106.25 RUS74792.1 - 3e-35 121.5 0.1 2e-34 118.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS74792.1 - 2e-21 76.6 0.0 7.2e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS74792.1 - 5.2e-09 36.3 0.0 8.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS74792.1 - 0.00032 20.3 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Complex1_49kDa PF00346.19 RUS74792.1 - 0.18 10.9 0.0 0.47 9.5 0.0 1.6 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit zf-C2H2_4 PF13894.6 RUS74793.1 - 1e-12 47.8 103.1 0.018 15.8 0.8 12.8 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS74793.1 - 3.1e-10 39.9 111.9 0.019 15.4 2.4 13.1 13 0 0 13 13 13 10 Zinc finger, C2H2 type zf-CRD PF17979.1 RUS74793.1 - 1.4e-06 28.5 44.5 0.13 12.4 0.2 8.7 8 2 1 10 10 10 6 Cysteine rich domain with multizinc binding regions zf-met PF12874.7 RUS74793.1 - 6.1e-06 26.5 78.3 0.9 10.0 4.8 10.8 10 0 0 10 10 10 8 Zinc-finger of C2H2 type Collagen PF01391.18 RUS74793.1 - 0.027 14.2 0.4 0.053 13.3 0.4 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) zf-H2C2_5 PF13909.6 RUS74793.1 - 0.067 13.0 13.7 3 7.7 3.3 4.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Cwf_Cwc_15 PF04889.12 RUS74793.1 - 0.19 11.4 6.5 0.75 9.5 6.5 2.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cation_efflux PF01545.21 RUS74794.1 - 1.3e-19 70.7 0.5 1.7e-19 70.3 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.12 RUS74794.1 - 0.014 15.3 1.6 0.017 15.1 0.1 1.9 2 0 0 2 2 2 0 XPA protein C-terminus Carb_kinase PF01256.17 RUS74795.1 - 2.4e-57 194.2 0.0 2.9e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 RUS74795.1 - 9e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 RUS74795.1 - 0.0014 18.0 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF1764 PF08576.10 RUS74796.1 - 0.59 11.1 25.3 0.11 13.3 17.9 2.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) YL1 PF05764.13 RUS74796.1 - 0.97 9.5 29.2 1.7 8.7 25.2 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Rtf2 PF04641.12 RUS74796.1 - 2.5 7.4 18.1 1.1 8.5 14.8 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger OATP PF03137.20 RUS74796.1 - 5.9 5.0 7.5 65 1.6 0.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_LBD PF02931.23 RUS74797.1 - 1.4e-58 197.9 0.8 1.9e-32 112.5 0.1 2.5 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS74797.1 - 2e-39 136.1 2.1 1.1e-18 68.3 0.2 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HDOD PF08668.12 RUS74797.1 - 1.5e-05 24.5 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 HDOD domain DUF4381 PF14316.6 RUS74797.1 - 7e-05 23.1 0.0 0.62 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) Pol_alpha_B_N PF08418.10 RUS74797.1 - 0.0003 20.8 7.4 0.11 12.5 0.5 2.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal CitMHS PF03600.16 RUS74797.1 - 0.00043 19.6 1.0 0.71 9.0 0.0 2.5 2 1 0 2 2 2 2 Citrate transporter CoA_binding_3 PF13727.6 RUS74797.1 - 0.0026 17.8 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 2 CoA-binding domain NAM-associated PF14303.6 RUS74797.1 - 0.004 17.9 0.1 2.6 8.7 0.0 2.1 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain NicO PF03824.16 RUS74797.1 - 0.0046 16.3 0.7 2 7.7 0.2 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein DUF4231 PF14015.6 RUS74797.1 - 0.012 16.1 0.2 11 6.6 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF4231) DUF4834 PF16118.5 RUS74797.1 - 0.018 16.0 0.1 17 6.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2678 PF10856.8 RUS74797.1 - 0.023 14.6 4.0 4 7.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) TssO PF17561.2 RUS74797.1 - 0.03 14.4 0.7 14 5.8 0.1 2.9 2 0 0 2 2 2 0 Type VI secretion system, TssO C_Hendra PF16821.5 RUS74797.1 - 0.11 12.4 4.6 4.8 7.0 0.5 2.2 2 0 0 2 2 2 0 C protein from hendra and measles viruses TMEM100 PF16311.5 RUS74797.1 - 0.17 11.5 0.6 23 4.6 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein 100 SYF2 PF08231.12 RUS74797.1 - 0.38 11.1 7.3 6.5 7.1 1.5 2.2 2 0 0 2 2 2 0 SYF2 splicing factor ABC2_membrane_5 PF13346.6 RUS74797.1 - 1.3 8.5 17.3 3.3 7.2 4.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.6 RUS74797.1 - 2.9 7.5 12.3 13 5.4 1.6 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4131) Bax1-I PF01027.20 RUS74797.1 - 6.4 6.5 12.7 12 5.6 2.5 2.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Voltage_CLC PF00654.20 RUS74798.1 - 2.9e-102 342.6 23.2 7.4e-101 337.9 19.7 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel zf-C2H2 PF00096.26 RUS74799.1 - 7.8e-17 60.7 22.4 2.8e-05 24.3 0.4 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS74799.1 - 6.1e-15 54.6 19.0 0.00066 20.3 1.1 5.7 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS74799.1 - 1.2e-12 47.7 16.8 4.1e-05 23.8 0.2 5.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS74799.1 - 1.5e-10 41.1 10.3 0.26 11.6 0.0 5.8 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 RUS74799.1 - 0.00037 20.5 8.6 0.0019 18.2 0.6 4.6 6 1 1 7 7 7 2 BED zinc finger zf-C2H2_6 PF13912.6 RUS74799.1 - 0.0014 18.6 13.0 0.27 11.3 1.5 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger GAGA PF09237.11 RUS74799.1 - 0.0099 15.7 1.1 0.059 13.2 0.2 2.5 1 1 1 2 2 2 1 GAGA factor zf-met PF12874.7 RUS74799.1 - 0.025 14.9 12.6 2.6 8.6 0.2 5.3 5 1 0 5 5 5 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 RUS74799.1 - 0.092 12.7 7.2 0.68 9.9 0.1 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TF_Zn_Ribbon PF08271.12 RUS74799.1 - 0.095 12.2 3.9 1.8 8.1 0.3 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2_2 PF12756.7 RUS74799.1 - 0.11 12.9 13.5 0.3 11.4 0.1 4.8 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) Ribosomal_S27e PF01667.17 RUS74799.1 - 0.18 11.6 4.7 54 3.6 0.0 4.0 3 1 1 4 4 4 0 Ribosomal protein S27 zf-H2C2_5 PF13909.6 RUS74799.1 - 0.26 11.1 14.4 14 5.5 0.1 4.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-CHCC PF10276.9 RUS74799.1 - 0.53 10.4 6.9 12 6.0 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger domain DUF4718 PF15842.5 RUS74799.1 - 0.83 9.4 3.6 1.7 8.4 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Zn_Tnp_IS91 PF14319.6 RUS74799.1 - 1.1 9.4 6.7 3.5 7.7 0.0 4.0 3 1 0 3 3 3 0 Transposase zinc-binding domain Arc_trans_TRASH PF08394.10 RUS74799.1 - 1.1 9.6 6.2 0.67 10.3 0.1 2.8 2 0 0 2 2 2 0 Archaeal TRASH domain ADK_lid PF05191.14 RUS74799.1 - 2.8 8.0 11.9 1.5e+02 2.4 11.9 3.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 RUS74799.1 - 2.8 8.1 7.2 26 5.0 0.2 3.5 3 1 1 4 4 3 0 Zinc ribbon domain Fer2 PF00111.27 RUS74800.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3449 PF11931.8 RUS74801.1 - 8.6e-73 244.1 0.3 8.6e-73 244.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 RUS74801.1 - 1.5e-29 101.4 1.0 3.6e-29 100.2 1.0 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 RUS74801.1 - 2.3e-23 82.5 4.3 2.3e-23 82.5 4.3 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 RUS74801.1 - 4.4e-05 23.3 0.2 0.00011 22.0 0.1 1.8 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain DUF5404 PF17397.2 RUS74801.1 - 0.025 14.7 2.3 0.064 13.4 2.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5404) Ank_2 PF12796.7 RUS74802.1 - 2.5e-15 56.8 0.5 1.6e-11 44.7 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS74802.1 - 1.9e-10 40.8 0.2 8.4e-06 26.0 0.1 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS74802.1 - 2.8e-10 39.5 0.0 0.012 16.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS74802.1 - 5e-09 36.2 0.2 0.0075 16.7 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RUS74802.1 - 8e-09 35.9 0.0 0.00061 20.3 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF3819 PF12842.7 RUS74802.1 - 0.011 15.7 0.2 0.025 14.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) eIF2_C PF09173.11 RUS74803.1 - 8.9e-37 125.2 0.5 2.4e-36 123.9 0.5 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 RUS74803.1 - 1.4e-23 83.5 0.8 1.1e-22 80.6 0.8 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RUS74803.1 - 3.2e-10 40.2 0.3 8.4e-10 38.9 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 RUS74803.1 - 0.00026 20.9 0.8 0.0081 16.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RUS74803.1 - 0.0037 17.3 0.0 0.0087 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 RUS74803.1 - 0.017 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 RUS74803.1 - 0.14 12.2 0.2 0.42 10.7 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Got1 PF04178.12 RUS74804.1 - 7.1e-35 119.9 22.6 3.2e-34 117.7 22.6 1.8 1 1 1 2 2 2 2 Got1/Sft2-like family ECF_trnsprt PF12822.7 RUS74804.1 - 0.19 11.8 15.6 0.26 11.4 15.6 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF4731 PF15875.5 RUS74804.1 - 1.9 8.8 5.0 6.8 7.0 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4731) DUF2614 PF11023.8 RUS74804.1 - 6 7.0 12.0 2.5 8.2 2.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain BTB_2 PF02214.22 RUS74806.1 - 8.6e-19 67.7 0.4 2.3e-18 66.3 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Atg14 PF10186.9 RUS74806.1 - 0.017 14.2 12.7 0.028 13.5 12.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BTB_3 PF16017.5 RUS74806.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain HAP1_N PF04849.13 RUS74806.1 - 0.36 10.0 25.2 0.57 9.3 25.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FapA PF03961.13 RUS74806.1 - 0.37 9.4 10.1 0.15 10.7 7.5 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 RUS74806.1 - 0.4 10.2 13.7 0.59 9.6 13.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 RUS74806.1 - 0.66 10.5 10.0 1 9.8 10.0 1.4 1 0 0 1 1 1 0 AAA domain Serine_rich PF08824.10 RUS74806.1 - 3.5 7.6 13.5 10 6.1 13.1 1.8 1 1 0 1 1 1 0 Serine rich protein interaction domain FAM76 PF16046.5 RUS74806.1 - 4.9 6.4 20.4 6.6 6.0 20.1 1.3 1 1 0 1 1 1 0 FAM76 protein Sugar_tr PF00083.24 RUS74807.1 - 2e-09 36.8 6.0 2.6e-09 36.5 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS74807.1 - 3.2e-09 36.2 9.5 3.8e-09 35.9 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans PF00520.31 RUS74810.1 - 1.3e-49 168.6 53.3 8.4e-28 97.2 30.6 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 RUS74810.1 - 0.0058 16.5 0.2 0.52 10.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair PKD_channel PF08016.12 RUS74810.1 - 1.5 7.5 53.4 1.6 7.3 30.5 5.2 2 2 0 2 2 2 0 Polycystin cation channel ARD PF03079.14 RUS74811.1 - 1.3e-29 103.4 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS74811.1 - 8.2e-10 38.3 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS74811.1 - 0.0062 16.4 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 RUS74811.1 - 0.062 13.7 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 RUS74811.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 RUS74811.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Fra10Ac1 PF09725.9 RUS74812.1 - 1.2e-53 180.4 4.0 2.5e-53 179.4 4.0 1.6 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 PriA_CRR PF18319.1 RUS74812.1 - 0.097 12.7 1.6 0.18 11.8 1.6 1.5 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain FAA_hydrolase PF01557.18 RUS74813.1 - 8.1e-64 215.3 0.0 9.1e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family eRF1_2 PF03464.15 RUS74815.1 - 7.9e-48 162.1 0.0 1.2e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RUS74815.1 - 6.8e-38 129.6 0.1 1.3e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 RUS74815.1 - 5.1e-20 71.8 0.0 8.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 RUS74815.1 - 2.8e-10 40.6 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 RUS74815.1 - 1.2e-08 35.3 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 SBP_bac_11 PF13531.6 RUS74815.1 - 0.072 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Glycos_transf_2 PF00535.26 RUS74816.1 - 1.4e-27 96.5 0.0 2.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS74816.1 - 2.3e-09 37.5 0.0 5.7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS74816.1 - 1.6e-06 27.7 0.0 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS74816.1 - 0.16 11.4 0.0 0.93 8.9 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase like family 2 TTL PF03133.15 RUS74817.1 - 1.2e-86 290.6 0.3 2.6e-86 289.4 0.3 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS74817.1 - 1.6e-05 24.3 0.1 0.001 18.4 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS74817.1 - 6.6e-05 22.3 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp SCIFF PF13165.6 RUS74818.1 - 0.087 12.8 0.4 0.087 12.8 0.4 3.8 2 1 0 2 2 2 0 Six-cysteine peptide SCIFF Vitellogenin_N PF01347.22 RUS74819.1 - 2.3e-30 105.6 0.3 2.9e-30 105.3 0.3 1.0 1 0 0 1 1 1 1 Lipoprotein amino terminal region CpeT PF06206.11 RUS74819.1 - 0.069 13.1 0.4 0.73 9.8 0.0 2.5 3 0 0 3 3 3 0 CpeT/CpcT family (DUF1001) TPR_2 PF07719.17 RUS74820.1 - 0.0056 16.7 8.0 0.11 12.7 1.4 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 RUS74820.1 - 0.0082 15.7 0.9 0.072 12.6 0.1 2.0 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.6 RUS74820.1 - 0.086 12.9 3.4 14 5.9 4.3 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 RUS74820.1 - 0.46 10.6 2.7 33 4.8 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS74820.1 - 1.1 9.7 9.0 6.3 7.3 0.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS74820.1 - 1.2 9.1 3.5 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74820.1 - 5.8 6.9 10.5 1.1 9.2 1.8 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS74821.1 - 8.6e-12 45.2 0.3 0.00018 21.7 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS74821.1 - 5.5e-11 41.8 2.6 0.028 14.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS74821.1 - 4.3e-10 40.1 1.1 0.005 17.4 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS74821.1 - 1.3e-09 37.5 3.7 0.003 17.3 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS74821.1 - 3e-08 34.0 8.6 0.016 15.7 0.2 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS74821.1 - 1.5e-06 28.5 1.7 0.061 14.0 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS74821.1 - 4.5e-06 26.2 0.9 0.0034 17.0 0.0 3.5 3 1 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 RUS74821.1 - 5.1e-06 26.9 2.7 0.11 13.3 0.1 4.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74821.1 - 5.8e-05 22.9 2.6 7.9 6.9 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS74821.1 - 0.0001 22.0 0.0 13 6.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 RUS74821.1 - 0.00066 20.0 1.3 0.54 10.6 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS74821.1 - 0.0014 18.8 0.6 0.016 15.4 0.3 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 RUS74821.1 - 0.0015 18.0 2.7 0.06 12.7 0.4 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 RUS74821.1 - 0.0023 17.7 2.5 0.53 10.0 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 RUS74821.1 - 0.0083 16.3 0.4 0.29 11.3 0.2 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS74821.1 - 0.01 15.1 0.6 0.037 13.3 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 RUS74821.1 - 0.011 15.9 1.7 0.062 13.5 0.8 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_17 PF13431.6 RUS74821.1 - 0.018 15.4 0.8 12 6.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS74821.1 - 0.04 13.8 0.4 2.7 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat YL1 PF05764.13 RUS74821.1 - 0.075 13.1 14.5 0.19 11.8 14.5 1.7 1 0 0 1 1 1 0 YL1 nuclear protein BTAD PF03704.17 RUS74821.1 - 0.081 13.4 0.1 0.31 11.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial transcriptional activator domain DUF2989 PF11207.8 RUS74821.1 - 0.14 11.9 1.4 6.3 6.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) Pkinase PF00069.25 RUS74822.1 - 2.9e-70 236.6 0.0 3.9e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS74822.1 - 1.5e-36 126.0 0.0 2.6e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS74822.1 - 1.5e-05 24.1 0.2 2.3e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS74822.1 - 8.1e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS74822.1 - 0.0016 17.9 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS74822.1 - 0.093 12.6 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.20 RUS74824.1 - 5.4e-14 52.1 11.8 5.4e-14 52.1 11.8 3.8 4 2 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Ion_trans PF00520.31 RUS74825.1 - 1.8e-165 548.1 78.0 2.9e-63 213.4 22.8 3.1 3 0 0 3 3 3 3 Ion transport protein Na_trans_assoc PF06512.13 RUS74825.1 - 7.4e-12 46.0 6.1 7.4e-12 46.0 6.1 3.2 2 1 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.12 RUS74825.1 - 2.3e-10 39.8 68.9 0.0069 15.1 3.3 7.3 4 3 2 7 7 7 7 Polycystin cation channel GPHH PF16905.5 RUS74825.1 - 0.0028 17.4 0.1 0.0059 16.4 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2321 PF10083.9 RUS74825.1 - 0.41 10.3 2.9 0.75 9.4 2.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) SH2 PF00017.24 RUS74826.1 - 1.1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain TRAM_LAG1_CLN8 PF03798.16 RUS74827.1 - 2e-38 132.1 29.4 2.8e-38 131.6 29.4 1.2 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 RUS74827.1 - 0.012 15.4 0.2 0.028 14.3 0.2 1.5 1 0 0 1 1 1 0 Homeodomain Homeobox_KN PF05920.11 RUS74827.1 - 0.12 12.3 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF1003 PF06210.11 RUS74827.1 - 9.5 6.4 8.9 2.3 8.4 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) 7tm_2 PF00002.24 RUS74828.1 - 9.7e-23 80.7 16.0 4e-21 75.4 16.0 2.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS74828.1 - 1.1e-08 35.2 4.7 1.1e-08 35.2 4.7 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF4131 PF13567.6 RUS74828.1 - 3.2 7.4 7.2 14 5.3 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BTB_2 PF02214.22 RUS74829.1 - 1.3e-19 70.3 0.2 4.1e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 RUS74829.1 - 0.00011 22.2 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain YscO-like PF16789.5 RUS74829.1 - 0.025 14.6 8.0 0.04 14.0 8.0 1.3 1 0 0 1 1 1 0 YscO-like protein DUF2968 PF11180.8 RUS74829.1 - 0.24 11.0 4.7 0.47 10.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4140 PF13600.6 RUS74829.1 - 1.4 9.4 6.9 7.7 7.0 6.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.6 RUS74829.1 - 2.6 8.1 5.0 4.1 7.5 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) eIF-4B PF06273.11 RUS74829.1 - 4.5 6.2 8.1 5.4 6.0 8.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B MLVIN_C PF18697.1 RUS74830.1 - 0.0017 18.4 0.0 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Bd3614-deam PF14439.6 RUS74830.1 - 0.74 9.9 2.8 3.5 7.7 0.1 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase DBB PF14545.6 RUS74831.1 - 1.7e-07 31.2 0.3 4.2e-07 30.0 0.3 1.6 1 1 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Peptidase_C26 PF07722.13 RUS74832.1 - 2.7e-17 63.3 0.2 1.8e-13 50.8 0.0 2.4 2 1 0 2 2 2 2 Peptidase C26 GATase PF00117.28 RUS74832.1 - 0.00017 21.4 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 RUS74832.1 - 0.07 13.2 0.0 0.093 12.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.19 RUS74832.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family EF_assoc_2 PF08356.12 RUS74833.1 - 3.7e-34 116.6 0.0 9.1e-34 115.3 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 RUS74833.1 - 1.7e-26 92.7 0.1 6.5e-20 71.4 0.0 2.7 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 RUS74833.1 - 1.1e-25 89.0 1.3 8e-25 86.2 0.5 2.3 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 RUS74833.1 - 1.9e-13 50.7 0.0 5e-10 39.6 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 RUS74833.1 - 2.5e-08 33.2 0.1 0.00014 21.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain Arf PF00025.21 RUS74833.1 - 1.7e-07 30.9 0.1 2.8e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_1 PF00036.32 RUS74833.1 - 2.4e-07 29.8 0.8 0.0013 18.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS74833.1 - 6e-07 29.8 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair SRPRB PF09439.10 RUS74833.1 - 2e-06 27.4 0.1 5.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RUS74833.1 - 2.3e-06 27.4 0.5 0.0074 16.0 0.0 3.1 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 RUS74833.1 - 3.6e-05 23.8 0.0 0.013 15.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_5 PF13202.6 RUS74833.1 - 0.00038 19.8 1.1 0.024 14.1 0.0 2.7 2 0 0 2 2 2 1 EF hand AAA_14 PF13173.6 RUS74833.1 - 0.00093 19.2 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 RUS74833.1 - 0.0062 15.9 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 RUS74833.1 - 0.019 15.3 0.0 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 RUS74833.1 - 0.029 14.6 0.0 0.62 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RUS74833.1 - 0.12 11.9 0.0 8.1 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 RUS74833.1 - 0.18 11.7 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 RUS74833.1 - 0.18 11.8 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family EF-hand_10 PF14788.6 RUS74833.1 - 0.21 11.5 0.7 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 EF hand DUF3161 PF11362.8 RUS74834.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) TPT PF03151.16 RUS74835.1 - 9.9e-12 44.8 15.7 1.3e-11 44.4 15.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RUS74835.1 - 3.8e-05 23.0 2.2 4e-05 22.9 1.0 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter PsaX PF08078.12 RUS74835.1 - 0.061 13.3 0.6 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 PsaX family Ank_2 PF12796.7 RUS74837.1 - 5.8e-72 238.3 18.8 9e-13 48.6 0.1 9.2 2 2 7 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS74837.1 - 1.9e-67 222.8 15.5 6.7e-09 36.1 0.0 11.8 7 2 5 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS74837.1 - 9.5e-53 170.0 7.0 0.00034 20.8 0.0 15.7 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 RUS74837.1 - 7e-51 169.6 5.6 1.9e-08 34.4 0.0 10.0 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RUS74837.1 - 8.3e-48 158.8 11.8 0.00013 22.2 0.0 14.7 14 1 0 14 14 14 12 Ankyrin repeat SOCS_box PF07525.16 RUS74837.1 - 1.1e-05 25.7 0.1 1.1e-05 25.7 0.1 2.4 3 0 0 3 3 3 1 SOCS box Paf67 PF10255.9 RUS74838.1 - 2.1e-174 580.3 7.3 2.9e-174 579.8 7.3 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 RUS74838.1 - 0.031 14.1 0.1 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS74838.1 - 0.055 13.6 0.2 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS74838.1 - 0.062 13.4 1.3 0.86 9.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF573 PF04504.14 RUS74838.1 - 0.22 12.2 2.9 4 8.2 1.3 3.6 4 1 0 4 4 4 0 Protein of unknown function, DUF573 CTK3 PF12243.8 RUS74839.1 - 0.048 13.6 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 AP1AR PF15745.5 RUS74840.1 - 1.5e-20 74.0 19.4 5.7e-20 72.1 19.4 1.7 1 1 0 1 1 1 1 AP-1 complex-associated regulatory protein Eapp_C PF10238.9 RUS74840.1 - 0.48 10.5 2.9 0.95 9.5 2.6 1.8 1 1 0 1 1 1 0 E2F-associated phosphoprotein Menin PF05053.13 RUS74840.1 - 1.4 7.2 8.3 1.7 6.9 8.3 1.0 1 0 0 1 1 1 0 Menin Spc7 PF08317.11 RUS74842.1 - 3.3e-06 26.2 12.6 3.3e-06 26.2 12.6 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein Tropomyosin PF00261.20 RUS74842.1 - 0.011 15.2 11.7 0.019 14.3 11.7 1.4 1 0 0 1 1 1 0 Tropomyosin FapA PF03961.13 RUS74842.1 - 0.016 13.8 6.7 0.02 13.5 6.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 RUS74842.1 - 0.022 14.8 17.4 0.046 13.7 15.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.9 RUS74842.1 - 0.049 12.7 13.2 0.072 12.2 13.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 RUS74842.1 - 0.088 12.7 18.1 0.54 10.1 4.0 2.8 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Prominin PF05478.11 RUS74842.1 - 0.19 9.7 14.5 0.31 8.9 14.5 1.3 1 1 0 1 1 1 0 Prominin ARGLU PF15346.6 RUS74842.1 - 0.33 10.8 13.7 0.17 11.8 9.9 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Nucleo_P87 PF07267.11 RUS74842.1 - 0.39 9.5 9.0 0.45 9.3 9.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LMBR1 PF04791.16 RUS74842.1 - 0.41 9.5 7.8 0.49 9.2 7.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3993 PF13158.6 RUS74842.1 - 0.51 10.6 6.1 4 7.7 0.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3993) SOBP PF15279.6 RUS74842.1 - 0.57 10.7 15.3 0.78 10.3 15.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein KxDL PF10241.9 RUS74842.1 - 0.73 10.2 17.5 0.94 9.8 0.9 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein FAP PF07174.11 RUS74842.1 - 0.83 9.0 15.8 1.1 8.6 15.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DegQ PF08181.11 RUS74842.1 - 0.92 9.7 10.8 3.8 7.7 4.1 2.9 1 1 1 2 2 2 0 DegQ (SacQ) family GAS PF13851.6 RUS74842.1 - 0.95 8.8 20.9 2.8 7.2 20.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 RUS74842.1 - 1.4 9.4 20.0 4.1 7.8 20.0 1.9 1 1 0 1 1 1 0 Fez1 DUF4201 PF13870.6 RUS74842.1 - 1.5 8.6 20.3 3.2 7.5 20.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) COG2 PF06148.11 RUS74842.1 - 2.3 8.3 10.6 3.8 7.6 7.2 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MIP-T3_C PF17749.1 RUS74842.1 - 2.8 7.9 15.5 0.2 11.6 4.2 3.0 1 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region COG5 PF10392.9 RUS74842.1 - 2.9 8.1 16.4 15 5.7 15.9 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Filament PF00038.21 RUS74842.1 - 5.7 6.4 18.0 3.8 7.0 12.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein TBCA PF02970.16 RUS74842.1 - 5.7 7.3 14.5 9.9 6.6 8.8 3.2 2 1 0 3 3 3 0 Tubulin binding cofactor A Fib_alpha PF08702.10 RUS74842.1 - 6 7.1 18.9 3.8 7.7 15.8 2.2 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family Nuf2 PF03800.14 RUS74845.1 - 0.057 13.5 0.5 0.071 13.2 0.5 1.2 1 0 0 1 1 1 0 Nuf2 family DUF5367 PF17329.2 RUS74848.1 - 0.0023 18.0 2.7 16 5.7 0.0 3.4 1 1 3 4 4 4 3 Family of unknown function (DUF5367) GUN4_N PF16416.5 RUS74848.1 - 0.0055 16.7 2.9 10 6.2 0.1 3.2 1 1 2 3 3 3 3 ARM-like repeat domain, GUN4-N terminal IBV_3A PF03617.13 RUS74848.1 - 0.0057 16.6 2.4 24 5.0 0.0 3.6 1 1 3 4 4 4 0 IBV 3A protein Hrs_helical PF12210.8 RUS74848.1 - 0.018 15.6 0.0 7.6 7.1 0.0 2.4 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TetR_C_8 PF14278.6 RUS74848.1 - 0.06 13.5 1.1 1.5e+02 2.5 0.0 4.0 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region DpaA_N PF16924.5 RUS74848.1 - 0.065 13.3 0.2 26 5.0 0.0 2.6 1 1 2 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain rve_2 PF13333.6 RUS74848.1 - 0.16 12.1 8.9 63 3.9 0.1 4.1 4 0 0 4 4 4 0 Integrase core domain DUF5021 PF16424.5 RUS74848.1 - 6.3 6.6 5.3 96 2.8 1.8 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5021) MULE PF10551.9 RUS74849.1 - 7.3e-19 68.0 0.9 2.6e-18 66.2 0.2 2.4 2 0 0 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 RUS74849.1 - 2.6e-14 53.0 3.8 3.5e-13 49.3 3.8 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RUS74849.1 - 2.7e-08 33.8 1.5 8.7e-08 32.2 1.5 1.8 1 1 0 1 1 1 1 Transposase Transposase_mut PF00872.18 RUS74849.1 - 6e-05 22.1 0.4 0.00065 18.7 0.1 2.1 2 0 0 2 2 2 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.6 RUS74849.1 - 0.0014 18.9 1.7 0.051 13.8 1.7 2.5 1 1 0 1 1 1 1 DDE domain SWIM PF04434.17 RUS74849.1 - 0.0027 17.3 0.1 0.0079 15.8 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.15 RUS74849.1 - 0.014 16.1 2.3 0.043 14.5 2.3 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain SeqA PF03925.13 RUS74849.1 - 0.14 12.2 0.8 0.29 11.1 0.8 1.5 1 0 0 1 1 1 0 SeqA protein C-terminal domain Hydrolase_like PF13242.6 RUS74851.1 - 3.7e-12 46.1 0.1 1.3e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 RUS74851.1 - 0.00066 19.8 0.0 0.0014 18.7 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS74851.1 - 0.031 14.5 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase V-set_CD47 PF08204.11 RUS74851.1 - 0.095 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain YajC PF02699.15 RUS74851.1 - 1.1 9.1 6.4 18 5.3 1.6 2.9 2 1 1 3 3 3 0 Preprotein translocase subunit MADF_DNA_bdg PF10545.9 RUS74852.1 - 3.6e-19 68.8 0.0 7.2e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS74852.1 - 0.041 13.7 0.2 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 BESS motif MFS_1 PF07690.16 RUS74853.1 - 5.5e-32 111.1 65.9 4.6e-14 52.1 13.4 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF417 PF04224.12 RUS74853.1 - 0.072 12.6 3.2 0.19 11.2 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF417 MBT PF02820.18 RUS74854.1 - 2.9e-52 174.9 0.0 8.6e-26 90.1 0.0 2.3 2 0 0 2 2 2 2 mbt repeat SLED PF12140.8 RUS74854.1 - 4.9e-26 91.4 0.4 8.6e-26 90.7 0.4 1.4 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 RUS74854.1 - 3.5e-13 49.8 0.2 6.2e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS74854.1 - 7e-05 22.9 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RUS74854.1 - 0.00025 20.9 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain DUF2387 PF09526.10 RUS74854.1 - 0.074 13.2 0.6 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) HapK PF11639.8 RUS74854.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 REDY-like protein HapK Pap_E4 PF02711.14 RUS74854.1 - 3.1 8.8 6.0 4.9 8.2 0.4 2.5 2 0 0 2 2 2 0 E4 protein NDUF_B4 PF07225.12 RUS74855.1 - 8e-13 48.4 0.1 9.7e-13 48.1 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Toxin_9 PF02819.15 RUS74856.1 - 5.5e-05 23.4 11.1 0.00011 22.4 11.1 1.6 1 1 0 1 1 1 1 Spider toxin Toxin_35 PF10530.9 RUS74856.1 - 0.093 12.7 14.2 0.79 9.7 14.2 2.3 1 1 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold GDA1_CD39 PF01150.17 RUS74857.1 - 1.2e-48 165.9 0.0 1.6e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.17 RUS74858.1 - 5.7e-66 222.9 0.0 7.7e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SecD-TM1 PF13721.6 RUS74858.1 - 0.97 9.9 4.8 20 5.7 0.4 2.8 2 1 1 3 3 3 0 SecD export protein N-terminal TM region DUF4834 PF16118.5 RUS74858.1 - 1 10.4 3.0 9.6 7.2 2.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) UvrB PF12344.8 RUS74858.1 - 2.3 8.1 12.2 1e+02 2.8 0.0 5.7 7 0 0 7 7 7 0 Ultra-violet resistance protein B EPL1 PF10513.9 RUS74859.1 - 0.038 14.4 1.1 0.056 13.8 1.1 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 RUS74859.1 - 0.052 13.5 10.9 0.078 13.0 10.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 RUS74859.1 - 0.23 12.1 0.1 0.31 11.6 0.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 RUS74859.1 - 0.41 9.3 0.6 0.46 9.2 0.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 RUS74859.1 - 0.72 10.8 3.4 1.3 10.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 RUS74859.1 - 5 5.8 11.2 7.5 5.3 11.2 1.3 1 0 0 1 1 1 0 Androgen receptor Peptidase_S49_N PF08496.10 RUS74859.1 - 6.6 6.8 7.0 10 6.2 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Insulin PF00049.18 RUS74860.1 - 0.0029 18.6 0.2 0.0068 17.4 0.2 1.7 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Jas PF16135.5 RUS74860.1 - 0.052 13.7 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Galactosyl_T PF01762.21 RUS74861.1 - 4.2e-45 154.0 0.0 1.1e-44 152.6 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase PH_15 PF17339.2 RUS74861.1 - 0.1 12.5 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 PH domain Galactosyl_T PF01762.21 RUS74862.1 - 6.7e-41 140.3 0.4 1.1e-39 136.3 0.4 2.5 1 1 0 1 1 1 1 Galactosyltransferase WD40_4 PF16300.5 RUS74862.1 - 0.18 11.7 0.2 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Type of WD40 repeat TMEM52 PF14979.6 RUS74866.1 - 0.044 13.7 0.3 0.059 13.3 0.3 1.1 1 0 0 1 1 1 0 Transmembrane 52 Laminin_EGF PF00053.24 RUS74867.1 - 0.003 17.6 68.8 31 4.8 10.8 5.9 1 1 3 4 4 4 3 Laminin EGF domain DUF5132 PF17195.4 RUS74868.1 - 0.016 15.3 8.4 30 4.8 0.0 5.4 2 2 3 5 5 5 0 Protein of unknown function (DUF5132) 4HBT PF03061.22 RUS74869.1 - 0.054 13.8 0.0 4.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily DUF681 PF05080.12 RUS74870.1 - 4.9e-07 30.3 12.7 65 4.3 0.1 9.2 1 1 11 12 12 12 11 Protein of unknown function (DUF681) Cren7 PF11520.8 RUS74871.1 - 8.7e-10 38.4 2.1 54 3.8 0.0 7.9 7 1 1 8 8 8 8 Chromatin protein Cren7 EF-hand_7 PF13499.6 RUS74872.1 - 3.8e-08 33.7 0.2 8.7e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS74872.1 - 1.1e-07 30.9 0.8 0.0074 15.8 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS74872.1 - 0.00021 20.9 0.1 0.0056 16.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RUS74872.1 - 0.00047 19.9 0.3 0.0014 18.5 0.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair DUF4499 PF14934.6 RUS74873.1 - 1.6e-18 66.8 0.9 2.2e-18 66.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) NADHdh PF00146.21 RUS74873.1 - 0.084 12.2 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase DnaJ PF00226.31 RUS74874.1 - 5.1e-06 26.5 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 RUS74874.1 - 0.0038 17.2 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3611 PF12263.8 RUS74874.1 - 0.034 14.0 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) PEP-CTERM PF07589.11 RUS74874.1 - 0.17 12.0 2.8 0.44 10.7 2.8 1.8 1 0 0 1 1 1 0 PEP-CTERM motif Guanylate_cyc PF00211.20 RUS74875.1 - 3.7e-21 75.6 0.0 4.3e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PARG_cat PF05028.14 RUS74876.1 - 4.7e-17 62.3 0.1 6.8e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PP_M1 PF03012.14 RUS74877.1 - 0.17 11.4 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Phosphoprotein Med21 PF11221.8 RUS74878.1 - 1.4 9.1 6.5 0.13 12.5 0.6 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Glyco_hydro_31 PF01055.26 RUS74879.1 - 0.064 12.4 0.3 0.074 12.2 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 PARG_cat PF05028.14 RUS74880.1 - 3.5e-51 174.5 0.0 4.1e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.14 RUS74881.1 - 1.2e-16 60.9 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) MNR PF15718.5 RUS74881.1 - 0.029 12.5 0.6 0.039 12.1 0.6 1.0 1 0 0 1 1 1 0 Protein moonraker Trypsin_2 PF13365.6 RUS74882.1 - 2.8e-05 25.1 0.2 0.00029 21.8 0.1 2.3 1 1 0 2 2 2 1 Trypsin-like peptidase domain Cyclin_N PF00134.23 RUS74883.1 - 9.8e-15 54.4 1.1 2.2e-11 43.6 0.3 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS74883.1 - 2.1e-05 24.6 0.1 0.00097 19.2 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 RUS74883.1 - 4e-05 23.6 0.4 0.021 14.9 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 RUS74883.1 - 0.018 15.4 0.1 0.09 13.2 0.0 2.2 2 1 0 2 2 2 0 Cyclin C-terminal domain TFIIB_C_1 PF18542.1 RUS74883.1 - 0.045 13.8 0.4 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 IstB_IS21 PF01695.17 RUS74884.1 - 0.036 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Myb_DNA-binding PF00249.31 RUS74885.1 - 7.4e-11 42.1 2.0 1.4e-05 25.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS74885.1 - 0.0049 17.1 0.3 0.043 14.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain FAM60A PF15396.6 RUS74885.1 - 0.012 15.6 2.5 0.034 14.1 0.6 1.9 1 1 1 2 2 2 0 Protein Family FAM60A MFS_1 PF07690.16 RUS74886.1 - 6.1e-16 58.3 37.0 3.9e-14 52.3 25.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 RUS74887.1 - 2.1e-97 326.6 0.6 1.8e-67 228.1 0.0 2.1 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 RUS74887.1 - 9.8e-08 32.1 0.0 2.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain VirB8 PF04335.13 RUS74887.1 - 0.018 14.8 0.7 0.047 13.5 0.7 1.6 1 0 0 1 1 1 0 VirB8 protein Cu_amine_oxid PF01179.20 RUS74888.1 - 2.3e-80 270.6 3.8 3e-80 270.2 3.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF5492 PF17596.2 RUS74888.1 - 0.18 12.1 2.3 0.37 11.1 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5492) Tropomyosin PF00261.20 RUS74889.1 - 5.4e-96 320.5 78.5 1.9e-89 299.2 54.0 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 RUS74889.1 - 3.4e-34 118.0 69.6 1e-31 110.0 35.6 2.6 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.12 RUS74889.1 - 8.8e-07 29.0 34.6 0.0034 17.4 11.6 3.8 1 1 3 4 4 4 3 Laminin Domain II DUF1664 PF07889.12 RUS74889.1 - 2.9e-05 24.1 29.2 0.0031 17.6 6.5 4.1 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) AAA_13 PF13166.6 RUS74889.1 - 0.00015 20.6 43.8 0.0025 16.6 24.4 2.1 1 1 1 2 2 2 2 AAA domain ATG16 PF08614.11 RUS74889.1 - 0.00018 21.8 55.8 0.0025 18.1 18.3 3.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 RUS74889.1 - 0.00035 19.9 42.2 0.0061 15.9 15.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) Myosin_tail_1 PF01576.19 RUS74889.1 - 0.00041 18.3 56.1 0.003 15.5 13.1 3.0 1 1 2 3 3 3 2 Myosin tail ERM PF00769.19 RUS74889.1 - 0.00045 20.1 67.1 0.002 18.0 26.0 2.5 2 1 0 2 2 2 1 Ezrin/radixin/moesin family EzrA PF06160.12 RUS74889.1 - 0.00052 18.3 44.3 0.033 12.4 8.1 2.8 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA MscS_porin PF12795.7 RUS74889.1 - 0.00083 19.0 46.2 0.16 11.5 17.4 2.7 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain DUF724 PF05266.14 RUS74889.1 - 0.00085 19.2 47.3 0.0024 17.7 16.9 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 RUS74889.1 - 0.0014 18.7 61.5 0.026 14.6 17.8 3.3 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 RUS74889.1 - 0.0016 18.8 7.2 0.0016 18.8 7.2 4.9 1 1 5 6 6 6 1 Snapin/Pallidin Spc7 PF08317.11 RUS74889.1 - 0.003 16.5 56.0 0.0052 15.7 26.3 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Fib_alpha PF08702.10 RUS74889.1 - 0.0038 17.4 30.6 0.06 13.5 3.6 3.6 1 1 1 3 3 3 2 Fibrinogen alpha/beta chain family OmpH PF03938.14 RUS74889.1 - 0.0048 17.2 17.9 0.0048 17.2 17.9 3.3 1 1 2 3 3 3 1 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 RUS74889.1 - 0.0053 16.4 56.6 0.098 12.3 17.4 3.8 1 1 3 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Bacillus_HBL PF05791.11 RUS74889.1 - 0.006 16.4 19.4 0.006 16.4 8.1 3.0 3 0 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 RUS74889.1 - 0.007 16.6 3.8 0.007 16.6 3.8 3.8 1 1 2 3 3 3 1 Domain of unknown function (DUF5082) DHR10 PF18595.1 RUS74889.1 - 0.0073 16.4 27.7 0.0073 16.4 27.7 3.6 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 RUS74889.1 - 0.0088 16.0 6.2 0.0088 16.0 6.2 5.8 1 1 4 6 6 6 2 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 RUS74889.1 - 0.012 15.9 8.3 0.012 15.9 8.3 5.5 2 2 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HrpB7 PF09486.10 RUS74889.1 - 0.013 15.9 43.4 0.3 11.5 6.0 3.9 2 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 RUS74889.1 - 0.024 14.6 61.2 0.36 10.9 24.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 RUS74889.1 - 0.029 15.1 47.0 0.2 12.4 9.6 4.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4472) FliJ PF02050.16 RUS74889.1 - 0.037 14.3 41.4 0.49 10.6 8.4 3.6 2 2 1 3 3 3 0 Flagellar FliJ protein DUF16 PF01519.16 RUS74889.1 - 0.054 14.0 36.3 0.19 12.2 4.5 4.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF3142 PF11340.8 RUS74889.1 - 0.072 12.9 2.1 0.21 11.4 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3142) Golgin_A5 PF09787.9 RUS74889.1 - 0.078 12.4 50.5 0.24 10.8 20.3 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF745 PF05335.13 RUS74889.1 - 0.098 12.4 39.6 4 7.1 3.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Fez1 PF06818.15 RUS74889.1 - 0.099 13.1 50.9 0.063 13.7 19.5 2.8 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 RUS74889.1 - 0.12 11.8 55.7 0.14 11.5 29.1 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 RUS74889.1 - 0.13 12.7 61.6 0.042 14.2 20.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DMPK_coil PF08826.10 RUS74889.1 - 0.13 12.4 42.4 0.9 9.7 2.7 5.6 3 2 3 6 6 5 0 DMPK coiled coil domain like Gp58 PF07902.11 RUS74889.1 - 0.14 10.4 14.2 0.036 12.4 1.5 2.2 1 1 0 2 2 2 0 gp58-like protein FPP PF05911.11 RUS74889.1 - 0.17 10.0 53.7 1.6 6.8 24.6 2.4 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2721 PF11026.8 RUS74889.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.7 3 2 2 5 5 4 0 Protein of unknown function (DUF2721) DUF948 PF06103.11 RUS74889.1 - 0.19 12.0 21.0 0.41 10.9 0.9 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) MAD PF05557.13 RUS74889.1 - 0.19 10.0 55.0 0.026 12.9 22.1 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein ADIP PF11559.8 RUS74889.1 - 0.24 11.5 49.3 0.89 9.6 7.1 3.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding SH3BP5 PF05276.14 RUS74889.1 - 0.25 11.1 35.2 0.14 11.9 12.2 3.1 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Exonuc_VII_L PF02601.15 RUS74889.1 - 0.27 10.8 34.7 1.5 8.3 15.2 2.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit XhlA PF10779.9 RUS74889.1 - 0.38 11.0 45.3 0.2 11.9 3.0 6.0 1 1 4 6 6 6 0 Haemolysin XhlA CCDC144C PF14915.6 RUS74889.1 - 0.38 9.8 48.5 0.36 9.9 31.5 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Uso1_p115_C PF04871.13 RUS74889.1 - 0.51 10.7 62.9 1.4 9.3 17.2 4.0 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.11 RUS74889.1 - 0.75 8.6 53.4 1.4 7.7 32.3 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 RUS74889.1 - 0.78 9.2 46.4 0.56 9.7 23.1 2.3 1 1 0 2 2 2 0 Leucine zipper Uds1 PF15456.6 RUS74889.1 - 0.8 9.9 44.0 2.3 8.4 17.7 3.7 1 1 2 3 3 3 0 Up-regulated During Septation NPV_P10 PF05531.12 RUS74889.1 - 0.82 10.2 19.9 3.8 8.0 5.5 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 RUS74889.1 - 0.94 10.0 38.0 1.2 9.6 15.4 3.7 1 1 2 3 3 3 0 Type III cell invasion protein SipB HemX PF04375.14 RUS74889.1 - 1.3 8.3 40.3 3 7.1 5.6 3.6 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 RUS74889.1 - 1.7 9.0 56.3 0.046 14.0 12.4 5.3 1 1 4 5 5 5 0 Domain of unknown function (DUF4164) Alanine_zipper PF11839.8 RUS74889.1 - 1.7 9.0 31.4 2.1 8.8 3.7 4.9 3 1 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein HOOK PF05622.12 RUS74889.1 - 1.7 6.7 52.9 0.54 8.3 15.1 2.8 1 1 2 3 3 3 0 HOOK protein TMPIT PF07851.13 RUS74889.1 - 2.2 7.4 35.4 1.5 8.0 8.2 3.0 1 1 1 3 3 3 0 TMPIT-like protein BST2 PF16716.5 RUS74889.1 - 2.4 8.8 42.7 0.065 13.8 4.7 4.6 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 ISG65-75 PF11727.8 RUS74889.1 - 2.5 7.3 39.3 0.12 11.6 8.3 3.1 1 1 2 3 3 3 0 Invariant surface glycoprotein SlyX PF04102.12 RUS74889.1 - 4 8.1 39.9 1.4 9.6 6.7 5.4 2 2 3 5 5 5 0 SlyX HU-CCDC81_bac_2 PF18175.1 RUS74889.1 - 4 7.4 12.9 0.5 10.3 0.7 4.2 3 2 2 5 5 4 0 CCDC81-like prokaryotic HU domain 2 BORCS7 PF16088.5 RUS74889.1 - 4.9 7.5 18.4 0.91 9.8 0.6 4.0 2 2 2 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF1978 PF09321.10 RUS74889.1 - 5 6.4 42.4 3.4 6.9 15.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) DUF812 PF05667.11 RUS74889.1 - 5.4 5.8 51.9 11 4.8 30.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) IFT57 PF10498.9 RUS74889.1 - 6.8 5.6 37.6 1.2 8.0 15.0 3.1 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 RUS74889.1 - 7.3 7.1 39.2 0.49 10.8 1.6 6.0 3 2 4 7 7 6 0 Flagella accessory protein C (FlaC) Mce4_CUP1 PF11887.8 RUS74889.1 - 9 5.7 8.5 5.6 6.3 0.6 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative BLOC1_2 PF10046.9 RUS74889.1 - 9.4 6.6 37.9 6.3 7.2 13.9 4.5 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRCT PF00533.26 RUS74890.1 - 1.1e-05 25.7 0.5 0.29 11.5 0.1 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS74890.1 - 0.00013 22.3 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RUS74890.1 - 0.19 11.6 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Ufm1 PF03671.14 RUS74894.1 - 1e-41 140.9 0.1 1.4e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein WD40_4 PF16300.5 RUS74895.1 - 1.6e-35 120.7 0.4 1.2e-17 63.5 0.1 2.6 2 0 0 2 2 2 2 Type of WD40 repeat DUF1899 PF08953.11 RUS74895.1 - 7.8e-26 89.7 0.0 2.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) WD40 PF00400.32 RUS74895.1 - 4.2e-21 74.9 7.6 0.00012 22.8 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS74895.1 - 2.2e-14 53.5 0.0 1e-06 28.9 0.0 5.0 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RUS74895.1 - 9.1e-06 25.0 0.0 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region Glyco_hydro_32N PF00251.20 RUS74895.1 - 0.0025 17.4 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Cytochrom_D1 PF02239.16 RUS74895.1 - 0.057 11.9 0.0 1.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain BING4CT PF08149.11 RUS74895.1 - 0.16 11.8 0.5 22 4.9 0.0 2.8 2 0 0 2 2 2 0 BING4CT (NUC141) domain IKI3 PF04762.12 RUS74895.1 - 0.21 9.5 0.2 4.8 5.0 0.1 2.4 3 0 0 3 3 3 0 IKI3 family ATG13 PF10033.9 RUS74896.1 - 2.5e-12 47.0 0.2 3.8e-05 23.5 0.1 3.0 1 1 1 2 2 2 2 Autophagy-related protein 13 HSP70 PF00012.20 RUS74897.1 - 0.0096 14.2 0.2 0.021 13.0 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 RUS74897.1 - 0.066 12.7 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PilM_2 PF11104.8 RUS74897.1 - 0.068 12.2 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; CKAP2_C PF15297.6 RUS74899.1 - 8.9e-08 31.6 0.0 8.9e-08 31.6 0.0 3.3 1 1 2 4 4 4 1 Cytoskeleton-associated protein 2 C-terminus TNF PF00229.18 RUS74901.1 - 3e-12 46.6 0.0 6.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Serglycin PF04360.12 RUS74901.1 - 0.56 10.1 5.8 0.29 11.1 0.3 2.6 3 0 0 3 3 3 0 Serglycin DUF2497 PF10691.9 RUS74903.1 - 1.4e-07 31.9 18.6 2.7e+03 -1.1 18.6 5.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2497) DUF445 PF04286.12 RUS74903.1 - 9.3e-06 25.7 27.4 7e-05 22.8 27.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF445) NFRKB_winged PF14465.6 RUS74904.1 - 0.031 14.5 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 NFRKB Winged Helix-like SMG1_N PF17229.2 RUS74905.1 - 0.23 12.2 4.1 46 4.8 0.1 3.4 1 1 3 4 4 4 0 Serine/threonine-protein kinase SMG1 N-terminal Plasmod_Pvs28 PF06247.11 RUS74905.1 - 2.8 8.3 39.9 26 5.2 1.4 8.8 1 1 4 5 5 5 0 Pvs28 EGF domain Borrelia_P83 PF05262.11 RUS74906.1 - 1.7 7.0 54.8 2.6 6.4 54.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.15 RUS74906.1 - 5.6 5.6 18.0 7.4 5.2 18.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ependymin PF00811.18 RUS74907.1 - 3e-16 59.8 0.0 4.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ependymin Fz PF01392.22 RUS74908.1 - 2.7e-09 37.6 0.6 5.3e-09 36.7 0.6 1.5 1 0 0 1 1 1 1 Fz domain CECR6_TMEM121 PF14997.6 RUS74909.1 - 4.3e-41 140.9 0.8 4.3e-41 140.9 0.8 1.8 2 0 0 2 2 2 1 CECR6/TMEM121 family NADH_dh_m_C1 PF15088.6 RUS74909.1 - 0.14 11.8 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial CECR6_TMEM121 PF14997.6 RUS74910.1 - 1.9e-31 109.4 1.7 3.9e-31 108.4 1.7 1.5 1 0 0 1 1 1 1 CECR6/TMEM121 family SbcD_C PF12320.8 RUS74910.1 - 0.2 12.0 0.6 0.55 10.6 0.1 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain WD40 PF00400.32 RUS74911.1 - 0.0025 18.6 4.6 4 8.5 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS74911.1 - 0.031 14.6 0.0 11 6.5 0.0 3.3 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Phospholip_B PF04916.13 RUS74914.1 - 2.9e-167 557.5 7.1 3.5e-167 557.2 7.1 1.0 1 0 0 1 1 1 1 Phospholipase B Mannosyl_trans3 PF11051.8 RUS74914.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative zf_UBZ PF18439.1 RUS74914.1 - 0.28 10.8 0.7 0.48 10.1 0.7 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger SpoIIID PF12116.8 RUS74915.1 - 0.00014 21.8 0.1 0.00041 20.4 0.1 1.8 2 1 0 2 2 2 1 Stage III sporulation protein D HTH_psq PF05225.16 RUS74915.1 - 0.00095 18.9 0.2 0.0024 17.6 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.20 RUS74915.1 - 0.0019 18.5 0.0 0.004 17.4 0.0 1.6 2 0 0 2 2 1 1 Transposase HTH_40 PF14493.6 RUS74915.1 - 0.0029 18.0 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 RUS74915.1 - 0.0029 17.0 0.0 0.0096 15.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 RUS74915.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 RUS74915.1 - 0.0062 16.6 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RUS74915.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 RUS74915.1 - 0.024 14.4 0.6 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_50 PF18024.1 RUS74915.1 - 0.026 14.1 0.3 0.083 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 RUS74915.1 - 0.028 14.5 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 RUS74915.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain MarR_2 PF12802.7 RUS74915.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 MarR family I-set PF07679.16 RUS74916.1 - 4.4e-17 61.9 0.0 1.4e-10 41.1 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74916.1 - 5e-12 46.3 0.0 3.4e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS74916.1 - 1.3e-08 34.9 0.0 0.0074 16.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS74916.1 - 9.9e-08 32.1 0.1 0.017 15.3 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS74916.1 - 0.0027 18.0 0.0 3.4 8.1 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS74916.1 - 0.018 15.1 0.0 0.091 12.8 0.0 2.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 RUS74916.1 - 0.029 14.4 2.8 0.3 11.1 0.3 2.8 1 1 1 2 2 2 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 RUS74916.1 - 0.053 13.8 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain HTH_psq PF05225.16 RUS74917.1 - 1e-12 47.6 0.0 6.4e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain PHD_2 PF13831.6 RUS74917.1 - 2.8e-05 23.6 3.8 2.8e-05 23.6 3.8 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RUS74917.1 - 4.9e-05 23.1 10.6 0.00012 21.9 10.6 1.7 1 0 0 1 1 1 1 PHD-finger HTH_28 PF13518.6 RUS74917.1 - 0.0016 18.6 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 RUS74917.1 - 0.0085 15.9 0.4 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 RUS74917.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Zn_ribbon_17 PF17120.5 RUS74917.1 - 0.45 10.2 7.2 1.2 8.9 7.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Caudo_TAP PF02413.17 RUS74917.1 - 0.52 10.5 3.5 1.4 9.1 3.5 1.7 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF2285 PF10074.9 RUS74917.1 - 0.62 10.7 0.0 0.62 10.7 0.0 2.7 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2285) C1_2 PF03107.16 RUS74917.1 - 0.98 9.8 7.7 6.7 7.1 4.4 2.9 2 0 0 2 2 2 0 C1 domain TFIIA PF03153.13 RUS74917.1 - 1 9.3 21.3 1.5 8.8 21.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYVE_2 PF02318.16 RUS74917.1 - 1.4 9.1 7.3 4.5 7.5 7.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_vIL-18BP PF05566.12 RUS74917.1 - 2.2 8.5 5.3 12 6.1 0.8 3.0 2 1 1 3 3 3 0 Orthopoxvirus interleukin 18 binding protein PH_13 PF16652.5 RUS74918.1 - 7.5e-05 22.6 0.0 0.00018 21.4 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 RUS74918.1 - 0.00035 20.4 0.0 0.00095 19.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 RUS74918.1 - 0.0006 19.9 0.3 0.0036 17.4 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 RUS74918.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Apolipoprotein PF01442.18 RUS74919.1 - 3.9e-07 30.1 0.1 6.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS74919.1 - 0.0013 18.8 5.7 0.036 14.1 0.1 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 RUS74919.1 - 0.014 15.2 2.4 1 9.2 1.7 3.1 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF3150 PF11348.8 RUS74919.1 - 0.037 13.2 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) SF-assemblin PF06705.11 RUS74919.1 - 0.059 12.7 1.6 0.096 12.0 1.6 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin DASH_Duo1 PF08651.10 RUS74919.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Duo1 hGDE_N PF14699.6 RUS74920.1 - 0.00027 21.0 0.3 0.8 9.9 0.1 2.6 1 1 1 2 2 2 2 N-terminal domain from the human glycogen debranching enzyme Phage_tail_2 PF06199.11 RUS74920.1 - 0.0016 18.6 0.1 1.4 9.0 0.0 2.3 1 1 1 2 2 2 2 Phage tail tube protein Ribosomal_S19e PF01090.19 RUS74920.1 - 0.0062 16.2 0.2 17 5.1 0.0 3.6 1 1 3 4 4 4 1 Ribosomal protein S19e DUF2368 PF10166.9 RUS74920.1 - 0.23 11.1 14.2 16 5.1 2.8 3.7 1 1 2 3 3 3 0 Uncharacterised conserved protein (DUF2368) DUF1062 PF06353.12 RUS74920.1 - 1.2 10.0 5.9 7.2 7.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) DUF5074 PF16819.5 RUS74920.1 - 8.5 6.5 11.4 35 4.5 2.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5074) PAN_1 PF00024.26 RUS74921.1 - 0.03 14.3 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 PAN domain GST_N PF02798.20 RUS74922.1 - 5.3e-07 29.9 1.3 2.9e-06 27.5 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS74922.1 - 7.6e-06 26.1 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS74922.1 - 0.00096 19.9 0.0 0.0032 18.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 RUS74922.1 - 0.0069 16.8 0.0 0.025 15.0 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain Collagen PF01391.18 RUS74923.1 - 1.2e-08 34.6 20.2 1.5e-08 34.3 16.6 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) adh_short PF00106.25 RUS74925.1 - 2.5e-49 167.4 2.0 2.5e-49 167.4 2.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS74925.1 - 1.7e-41 142.3 3.2 2.1e-41 142.1 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS74925.1 - 2e-09 37.6 0.6 3.3e-09 36.9 0.6 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS74925.1 - 9.6e-07 28.5 0.2 1.4e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS74925.1 - 0.0001 21.4 0.4 0.00015 20.8 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 RUS74925.1 - 0.00079 18.9 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 RUS74925.1 - 0.0037 17.2 0.9 0.01 15.7 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 RUS74925.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein ComP_DUS PF16732.5 RUS74926.1 - 0.27 12.2 1.0 28 5.7 0.0 2.3 2 0 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor zf-AD PF07776.15 RUS74927.1 - 0.028 14.7 0.4 0.078 13.2 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) RHINO PF15319.6 RUS74927.1 - 0.059 13.4 5.0 0.13 12.3 5.0 1.5 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Sushi PF00084.20 RUS74929.1 - 3.4e-28 98.0 33.3 7.9e-09 36.0 1.0 6.5 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) HRM PF02793.22 RUS74929.1 - 0.082 13.2 22.4 1.1 9.6 0.1 5.3 4 1 1 5 5 5 0 Hormone receptor domain Sushi PF00084.20 RUS74930.1 - 5.1e-14 52.6 26.9 9.4e-09 35.7 1.3 7.3 5 3 1 6 6 6 5 Sushi repeat (SCR repeat) TMF_DNA_bd PF12329.8 RUS74932.1 - 0.023 14.7 3.7 0.023 14.7 3.7 7.5 3 2 5 8 8 8 0 TATA element modulatory factor 1 DNA binding DASH_Hsk3 PF08227.11 RUS74932.1 - 0.063 13.7 0.5 0.063 13.7 0.5 6.9 7 2 2 9 9 9 0 DASH complex subunit Hsk3 like DUF3584 PF12128.8 RUS74932.1 - 0.3 8.5 67.8 0.2 9.2 24.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AdenylateSensor PF16579.5 RUS74932.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.3 2 1 1 3 3 3 0 Adenylate sensor of SNF1-like protein kinase ATG16 PF08614.11 RUS74932.1 - 0.76 10.0 90.5 0.086 13.1 10.8 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) PTR PF12789.7 RUS74932.1 - 9.4 6.4 9.8 4.5 7.4 0.6 3.5 3 1 0 3 3 3 0 Phage tail repeat like Tropomyosin_1 PF12718.7 RUS74933.1 - 0.0039 17.4 21.2 0.0039 17.4 21.2 3.5 1 1 2 3 3 3 1 Tropomyosin like Phage_GP20 PF06810.11 RUS74933.1 - 0.015 15.1 5.8 0.015 15.1 5.8 3.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 RUS74933.1 - 0.02 14.4 46.4 0.11 11.9 15.6 2.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Spc7 PF08317.11 RUS74933.1 - 1.5 7.7 50.6 0.013 14.4 25.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 RUS74933.1 - 2 7.0 39.2 3.3 6.3 39.1 1.3 1 1 0 1 1 1 0 AAA domain DMSP_lyase PF16867.5 RUS74933.1 - 5 6.8 11.5 0.05 13.2 2.0 2.3 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase NPV_P10 PF05531.12 RUS74933.1 - 5.2 7.6 18.0 0.19 12.2 1.1 4.1 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Flagellin_C PF00700.21 RUS74933.1 - 5.6 7.4 14.1 1.1 9.7 0.1 3.8 2 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region DUF244 PF03112.14 RUS74933.1 - 6.9 6.5 8.9 1.3 8.9 1.2 2.5 1 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Cnd1 PF12717.7 RUS74935.1 - 5.4e-29 101.3 11.3 1.4e-24 87.0 0.9 6.0 4 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 RUS74935.1 - 1.1e-07 32.0 0.1 0.015 15.6 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 RUS74935.1 - 4.6e-07 29.6 9.8 0.54 10.7 0.3 6.5 5 0 0 5 5 5 2 HEAT repeat Nipped-B_C PF12830.7 RUS74935.1 - 6.8e-06 26.2 0.3 3.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 RUS74935.1 - 0.00011 22.5 2.5 2 8.9 0.1 4.3 4 1 0 4 4 4 2 HEAT repeats Cnd3 PF12719.7 RUS74935.1 - 0.0041 16.4 0.1 0.012 14.8 0.1 1.9 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 RUS74935.1 - 0.012 15.8 0.3 29 4.9 0.0 5.0 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Symplekin_C PF12295.8 RUS74935.1 - 0.15 12.2 1.8 0.31 11.1 0.1 2.3 2 1 0 2 2 2 0 Symplekin tight junction protein C terminal FANCI_S2 PF14676.6 RUS74935.1 - 0.85 9.9 10.2 0.21 11.9 0.5 4.0 4 2 1 5 5 5 0 FANCI solenoid 2 HEAT_EZ PF13513.6 RUS74935.1 - 3.6 8.2 7.8 4.6 7.9 0.2 4.2 3 2 0 3 3 3 0 HEAT-like repeat TNFR_c6 PF00020.18 RUS74938.1 - 4.2e-06 27.1 2.7 1e-05 25.8 2.7 1.7 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region MAM PF00629.23 RUS74940.1 - 1e-42 145.8 0.0 2.6e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Sushi PF00084.20 RUS74940.1 - 1.5e-14 54.3 4.1 4.6e-08 33.6 0.2 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) DUF4643 PF15485.6 RUS74940.1 - 0.09 12.6 9.7 0.16 11.8 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) COX16 PF14138.6 RUS74940.1 - 0.2 12.2 0.1 0.36 11.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Shisa PF13908.6 RUS74940.1 - 0.33 11.2 13.5 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 RUS74940.1 - 2 8.3 0.0 2 8.3 0.0 3.5 2 1 1 3 3 3 0 TMEM154 protein family Asp PF00026.23 RUS74941.1 - 6.1e-123 410.3 0.7 6.9e-123 410.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RUS74941.1 - 7.5e-15 55.6 0.5 4.1e-13 49.9 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RUS74941.1 - 0.00011 22.8 0.2 1.7 9.3 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 RUS74941.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal GFO_IDH_MocA PF01408.22 RUS74944.1 - 1.7e-23 83.7 0.0 2.4e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 RUS74944.1 - 1.6e-06 28.6 0.0 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 RUS74944.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.17 RUS74944.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PHP_C PF13263.6 RUS74944.1 - 0.048 13.4 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 PHP-associated NAD_binding_3 PF03447.16 RUS74944.1 - 0.066 13.9 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ASC PF00858.24 RUS74945.1 - 1.2e-83 281.6 2.2 3.9e-60 204.1 0.1 2.1 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel adh_short PF00106.25 RUS74946.1 - 8.3e-28 97.2 0.5 8.9e-26 90.6 0.5 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS74946.1 - 2.4e-14 53.5 0.1 1.4e-12 47.7 0.1 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PCRF PF03462.18 RUS74947.1 - 2e-53 181.1 1.7 2e-53 181.1 1.7 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 RUS74947.1 - 3.2e-33 114.1 7.0 3.2e-33 114.1 7.0 2.0 2 1 1 3 3 3 1 RF-1 domain Sdh5 PF03937.16 RUS74947.1 - 0.028 14.4 0.6 0.067 13.2 0.6 1.6 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase EF-hand_6 PF13405.6 RUS74948.1 - 0.023 14.6 0.0 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 RUS74948.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.7 1 1 1 2 2 2 0 EF-hand domain pair 7tm_1 PF00001.21 RUS74949.1 - 2e-33 115.9 4.4 3.4e-19 69.2 3.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS74949.1 - 0.059 12.8 9.1 0.044 13.1 0.5 2.5 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS74949.1 - 0.17 11.5 8.6 0.2 11.2 5.2 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Cys_Met_Meta_PP PF01053.20 RUS74950.1 - 1.4e-125 418.8 0.0 1.7e-125 418.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RUS74950.1 - 1.3e-09 37.7 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RUS74950.1 - 7.7e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 RUS74950.1 - 0.0001 21.0 0.0 0.00052 18.7 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SBF2 PF12335.8 RUS74951.1 - 3.5e-08 33.3 0.1 3.9e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Myotubularin protein DUF3754 PF12576.8 RUS74952.1 - 4.3e-21 75.3 0.1 7.3e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Ldl_recept_a PF00057.18 RUS74953.1 - 5.5e-07 29.7 7.7 1.1e-06 28.7 7.7 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A 7tm_2 PF00002.24 RUS74954.1 - 8.6e-17 61.2 13.0 4.6e-16 58.9 13.0 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Arm PF00514.23 RUS74955.1 - 5.9e-06 26.1 0.0 0.074 13.1 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Dehalogenase PF13486.6 RUS74955.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit DUF3040 PF11239.8 RUS74955.1 - 1.3 9.4 9.2 3.4 8.0 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) zf-CCHC PF00098.23 RUS74956.1 - 5.1e-07 29.5 2.6 9.2e-07 28.7 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS74956.1 - 0.011 15.4 1.9 0.026 14.2 1.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 RUS74956.1 - 0.018 14.9 1.8 0.029 14.2 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 RUS74957.1 - 1.5e-06 28.0 1.8 2.7e-06 27.2 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS74957.1 - 1.3 8.9 6.4 0.13 12.1 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle p450 PF00067.22 RUS74958.1 - 5.6e-87 292.4 0.4 1.3e-85 287.9 0.4 2.1 1 1 0 1 1 1 1 Cytochrome P450 UTP25 PF06862.12 RUS74958.1 - 0.018 13.8 0.2 0.033 13.0 0.2 1.4 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 cNMP_binding PF00027.29 RUS74959.1 - 7.2e-21 74.1 0.0 5.8e-10 39.1 0.0 4.9 4 1 1 5 5 5 4 Cyclic nucleotide-binding domain PINIT PF14324.6 RUS74961.1 - 0.029 14.7 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 PINIT domain AAA_6 PF12774.7 RUS74962.1 - 5.7e-128 426.5 0.0 2e-127 424.7 0.0 2.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS74962.1 - 3.8e-115 385.2 4.2 3.8e-115 385.2 4.2 4.1 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RUS74962.1 - 4.8e-71 238.4 2.0 4.8e-71 238.4 2.0 3.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 RUS74962.1 - 5.5e-50 170.1 0.1 8.7e-49 166.2 0.0 3.3 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 RUS74962.1 - 5.4e-39 134.3 1.9 5.4e-39 134.3 1.9 3.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 Dynein_C PF18199.1 RUS74962.1 - 1.8e-38 132.5 0.0 1.8e-38 132.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 RUS74962.1 - 9.9e-37 125.7 0.0 4.1e-34 117.2 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 RUS74962.1 - 1.5e-36 125.7 0.0 3.4e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS74962.1 - 1.4e-34 119.0 0.1 1.4e-23 83.4 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 RUS74962.1 - 1.8e-32 112.7 10.1 1.8e-32 112.7 10.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RUS74962.1 - 1.5e-26 93.0 0.4 5e-23 81.5 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_16 PF13191.6 RUS74962.1 - 1.3e-09 38.7 7.9 0.014 15.8 0.0 6.7 6 1 1 7 7 5 3 AAA ATPase domain AAA_22 PF13401.6 RUS74962.1 - 4.6e-09 36.7 3.3 0.0022 18.2 0.0 5.0 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 RUS74962.1 - 1.7e-07 31.7 0.8 1.4 9.3 0.0 5.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RUS74962.1 - 5e-06 26.6 2.4 0.0026 17.7 0.0 3.8 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 RUS74962.1 - 4.7e-05 23.4 0.1 1.7 8.6 0.0 4.6 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_24 PF13479.6 RUS74962.1 - 5.5e-05 23.0 0.0 0.048 13.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS74962.1 - 0.00012 21.9 0.2 0.14 11.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 RUS74962.1 - 0.00036 20.8 0.0 0.0099 16.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RUS74962.1 - 0.0004 20.3 4.0 0.067 13.1 0.0 4.5 5 0 0 5 5 5 1 RsgA GTPase AAA_18 PF13238.6 RUS74962.1 - 0.00059 20.4 0.1 0.25 11.9 0.0 4.4 3 0 0 3 3 3 1 AAA domain ATG16 PF08614.11 RUS74962.1 - 0.0016 18.7 10.0 0.0016 18.7 10.0 4.1 3 0 0 3 3 1 1 Autophagy protein 16 (ATG16) NACHT PF05729.12 RUS74962.1 - 0.0055 16.6 0.1 7.6 6.4 0.1 4.4 3 0 0 3 3 3 0 NACHT domain T2SSE PF00437.20 RUS74962.1 - 0.0059 15.7 0.0 0.12 11.4 0.0 2.7 3 0 0 3 3 2 1 Type II/IV secretion system protein PhoH PF02562.16 RUS74962.1 - 0.017 14.6 0.4 0.12 11.8 0.0 2.5 3 0 0 3 3 2 0 PhoH-like protein RNA_helicase PF00910.22 RUS74962.1 - 0.019 15.4 0.2 5.8 7.4 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Dynein_AAA_lid PF17852.1 RUS74962.1 - 0.021 14.9 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain IstB_IS21 PF01695.17 RUS74962.1 - 0.028 14.1 0.5 1.2 8.9 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 RUS74962.1 - 0.03 14.5 1.2 1 9.5 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 RUS74962.1 - 0.042 13.6 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 RUS74962.1 - 0.043 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 AAA+ lid domain G-alpha PF00503.20 RUS74962.1 - 0.075 12.2 1.4 4.8 6.2 0.0 3.3 3 0 0 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 RUS74962.1 - 0.13 12.8 9.1 0.23 12.0 0.0 4.6 5 0 0 5 5 2 0 ABC transporter cobW PF02492.19 RUS74962.1 - 0.18 11.4 0.3 15 5.1 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 RUS74962.1 - 0.27 10.6 1.4 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TPD52 PF04201.15 RUS74962.1 - 7.1 6.2 13.9 0.53 9.9 3.2 3.4 3 0 0 3 3 2 0 Tumour protein D52 family Cullin_binding PF03556.15 RUS74963.1 - 1.5e-31 109.3 2.7 2.4e-31 108.7 2.7 1.3 1 0 0 1 1 1 1 Cullin binding DUF4485 PF14846.6 RUS74963.1 - 0.058 13.5 0.5 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) MTBP_C PF14920.6 RUS74964.1 - 0.26 11.0 7.7 2.7 7.7 0.3 2.5 2 1 0 2 2 2 0 MDM2-binding Rep_fac-A_C PF08646.10 RUS74965.1 - 5.1e-11 42.5 0.0 5.7e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-RING_4 PF14570.6 RUS74965.1 - 0.026 14.3 4.7 0.038 13.8 4.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FAM35_C PF15793.5 RUS74965.1 - 0.051 13.0 0.3 0.053 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein family FAM35, C-terminal Ribosomal_L40e PF01020.17 RUS74965.1 - 0.058 13.3 8.1 0.084 12.8 8.1 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Disintegrin PF00200.23 RUS74966.1 - 1.6e-06 28.8 16.2 1.6e-06 28.8 16.2 3.3 2 1 0 3 3 3 1 Disintegrin Disintegrin PF00200.23 RUS74967.1 - 2.3e-05 25.1 17.8 2.3e-05 25.1 17.8 3.3 2 1 1 3 3 3 1 Disintegrin zf-CCHC PF00098.23 RUS74968.1 - 6.2e-05 22.9 1.5 9.8e-05 22.3 1.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS74968.1 - 0.0042 16.8 1.9 0.0098 15.6 1.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 RUS74968.1 - 0.0047 16.9 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS74968.1 - 0.0088 15.8 1.2 0.013 15.3 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle FXR_C1 PF16096.5 RUS74968.1 - 5.3 7.3 8.6 14 6.0 8.6 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 zf-C2H2 PF00096.26 RUS74970.1 - 1.8e-30 103.6 63.5 6.2e-06 26.4 4.0 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS74970.1 - 4.1e-27 92.5 62.8 0.00061 20.4 2.2 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS74970.1 - 2.1e-23 81.6 55.7 3.5e-05 24.0 0.8 9.6 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS74970.1 - 5.5e-15 55.2 48.2 0.026 14.8 1.7 8.4 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS74970.1 - 7.3e-09 35.4 59.8 0.00017 21.5 2.1 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 RUS74970.1 - 4.3e-06 26.9 50.2 0.012 16.0 1.5 8.3 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS74970.1 - 0.0018 18.6 38.6 0.23 11.8 2.6 5.4 2 1 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 RUS74970.1 - 0.0043 17.4 46.7 1.4 9.3 0.6 7.4 1 1 6 7 7 7 4 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 RUS74970.1 - 0.015 14.9 29.0 7.2 6.3 0.1 7.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 RUS74970.1 - 0.079 13.1 0.0 0.079 13.1 0.0 4.6 5 1 1 6 6 6 0 Zic proteins zinc finger domain BolA PF01722.18 RUS74970.1 - 1 9.7 10.8 2.7 8.3 2.0 4.7 2 1 3 5 5 5 0 BolA-like protein LIM PF00412.22 RUS74970.1 - 3 8.1 40.5 4.4 7.6 1.7 6.0 2 2 2 5 5 5 0 LIM domain TF_Zn_Ribbon PF08271.12 RUS74970.1 - 5.5 6.6 11.4 1.1 8.8 1.2 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding CH PF00307.31 RUS74971.1 - 3.5e-23 81.8 0.0 4.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS74971.1 - 2.2e-06 27.4 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 RUS74972.1 - 0.052 13.7 0.7 0.089 13.0 0.7 1.5 1 1 0 1 1 1 0 Calponin homology (CH) domain Flexi_CP_N PF08358.10 RUS74974.1 - 0.00084 19.3 13.4 5.7 7.0 0.1 5.4 4 2 2 6 6 6 4 Carlavirus coat RNase_P_pop3 PF08228.11 RUS74974.1 - 0.025 14.6 10.9 24 5.0 0.3 5.3 4 2 2 6 6 6 0 RNase P subunit Pop3 MbtH PF03621.13 RUS74974.1 - 0.084 12.3 0.1 16 5.0 0.0 3.5 2 1 3 5 5 5 0 MbtH-like protein DUF3730 PF12530.8 RUS74975.1 - 4.6e-10 39.5 0.8 2 8.0 0.1 6.5 1 1 6 7 7 7 6 Protein of unknown function (DUF3730) HEAT_PBS PF03130.16 RUS74975.1 - 6.4e-08 32.5 27.0 1.1e+02 3.9 0.2 14.7 1 1 10 11 11 11 0 PBS lyase HEAT-like repeat Keratin_B2_2 PF13885.6 RUS74975.1 - 2.8e-06 27.2 91.5 3.4 7.7 16.6 5.7 1 1 3 4 4 4 3 Keratin, high sulfur B2 protein PAE PF03283.13 RUS74976.1 - 8.1e-76 255.4 0.0 1.2e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase CoA_binding_3 PF13727.6 RUS74977.1 - 0.36 10.8 2.6 0.29 11.1 0.8 1.8 2 0 0 2 2 2 0 CoA-binding domain DUF5455 PF17537.2 RUS74977.1 - 0.36 11.3 7.9 0.69 10.4 1.7 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5455) Peptidase_U4 PF03419.13 RUS74978.1 - 0.12 11.7 1.9 0.17 11.1 1.9 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Keratin_B2_2 PF13885.6 RUS74979.1 - 0.0036 17.2 208.0 1.7 8.7 22.1 8.4 1 1 8 9 9 9 7 Keratin, high sulfur B2 protein Pep_M12B_propep PF01562.19 RUS74980.1 - 3.9e-20 72.5 0.0 5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 RUS74981.1 - 4.8e-17 62.2 2.0 8.5e-17 61.4 2.0 1.4 1 0 0 1 1 1 1 ADAM cysteine-rich domain TSP_1 PF00090.19 RUS74981.1 - 4.7e-05 23.5 7.0 4.7e-05 23.5 7.0 2.3 2 1 0 2 2 2 1 Thrombospondin type 1 domain ADAM_CR PF08516.12 RUS74981.1 - 0.27 11.6 4.4 8.7 6.8 1.1 2.6 2 1 0 2 2 2 0 ADAM cysteine-rich Toxin_5 PF05294.13 RUS74981.1 - 1 9.8 7.0 1.1 9.7 0.9 2.7 2 0 0 2 2 2 0 Scorpion short toxin ShK PF01549.24 RUS74982.1 - 3.7e-15 56.2 68.6 0.00021 21.8 7.7 6.3 6 0 0 6 6 6 5 ShK domain-like CUB PF00431.20 RUS74982.1 - 1.5e-11 44.6 3.0 6.9e-10 39.3 0.0 3.7 5 0 0 5 5 5 1 CUB domain Apt1 PF10351.9 RUS74982.1 - 0.16 10.8 13.5 0.27 10.0 13.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Filament PF00038.21 RUS74983.1 - 5.1e-22 78.9 11.4 6.5e-22 78.5 11.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 RUS74983.1 - 0.0013 18.8 9.5 0.0013 18.8 9.5 1.9 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 RUS74983.1 - 0.0051 16.7 9.0 0.017 15.0 9.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.22 RUS74983.1 - 0.0075 16.5 11.4 0.012 15.9 11.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IMD PF08397.11 RUS74983.1 - 0.0099 15.3 8.1 0.0099 15.3 8.1 1.3 1 1 0 1 1 1 1 IRSp53/MIM homology domain DUF3450 PF11932.8 RUS74983.1 - 0.011 15.0 4.3 0.016 14.6 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 RUS74983.1 - 0.016 15.3 8.1 0.024 14.8 8.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RUS74983.1 - 0.018 13.9 13.6 0.023 13.6 13.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 RUS74983.1 - 0.027 14.6 3.6 0.033 14.3 2.3 1.7 1 1 1 2 2 2 0 MbeD/MobD like DUF5624 PF18538.1 RUS74983.1 - 0.032 14.3 1.6 0.05 13.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) bZIP_1 PF00170.21 RUS74983.1 - 0.042 13.9 3.3 0.042 13.9 3.3 3.0 1 1 1 2 2 2 0 bZIP transcription factor Laminin_II PF06009.12 RUS74983.1 - 0.045 13.8 9.3 0.15 12.0 7.4 2.0 1 1 1 2 2 2 0 Laminin Domain II KASH_CCD PF14662.6 RUS74983.1 - 0.068 13.0 14.2 0.1 12.4 14.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Exonuc_VII_L PF02601.15 RUS74983.1 - 0.074 12.6 2.1 0.085 12.4 2.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 RUS74983.1 - 0.094 12.8 6.8 0.18 11.8 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 RUS74983.1 - 0.11 12.9 8.5 1.1 9.7 2.8 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4446 PF14584.6 RUS74983.1 - 0.21 11.5 12.1 0.56 10.2 1.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) UPF0184 PF03670.13 RUS74983.1 - 0.22 12.0 2.8 0.81 10.1 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) TMPIT PF07851.13 RUS74983.1 - 0.25 10.6 11.2 0.33 10.1 11.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 RUS74983.1 - 0.35 11.3 4.9 19 5.8 4.9 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4535 PF15054.6 RUS74983.1 - 0.44 10.3 4.7 26 4.6 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) Prefoldin_2 PF01920.20 RUS74983.1 - 0.46 10.5 16.7 2.5 8.1 7.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit DUF948 PF06103.11 RUS74983.1 - 0.67 10.3 4.5 1.2 9.5 1.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FAP206 PF12018.8 RUS74983.1 - 0.74 9.3 7.2 1 8.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF2570 PF10828.8 RUS74983.1 - 1 9.2 9.1 1.9 8.4 7.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF883 PF05957.13 RUS74983.1 - 1.4 9.6 6.9 2.2 8.9 3.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 RUS74983.1 - 1.4 8.7 5.7 6 6.6 5.7 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain YlqD PF11068.8 RUS74983.1 - 1.7 9.0 11.9 13 6.1 12.4 1.9 1 1 1 2 2 2 0 YlqD protein Neur_chan_memb PF02932.16 RUS74983.1 - 1.9 8.5 5.6 2.5 8.1 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plk4_PB2 PF18409.1 RUS74983.1 - 1.9 9.2 6.9 4.5 8.0 1.3 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF4404 PF14357.6 RUS74983.1 - 2 9.1 8.3 1.2 9.8 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) bZIP_2 PF07716.15 RUS74983.1 - 2.3 8.4 20.2 0.1 12.7 7.2 3.2 2 1 0 2 2 2 0 Basic region leucine zipper APG6_N PF17675.1 RUS74983.1 - 2.7 8.5 16.6 5.2 7.6 16.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Rho_Binding PF08912.11 RUS74983.1 - 5.6 7.9 17.0 11 7.0 3.5 2.7 1 1 1 2 2 2 0 Rho Binding YabA PF06156.13 RUS74983.1 - 8.2 7.1 13.9 1.3e+02 3.2 4.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF3782 PF12644.7 RUS74983.1 - 8.4 6.6 7.5 30 4.9 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Filament PF00038.21 RUS74984.1 - 1.3e-58 199.1 60.2 2e-58 198.4 60.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 RUS74984.1 - 0.0016 18.5 13.4 0.0016 18.5 13.4 4.3 1 1 2 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 RUS74984.1 - 0.0028 16.6 17.3 0.0028 16.6 17.3 2.7 1 1 2 3 3 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 RUS74984.1 - 0.0045 17.0 7.8 0.0045 17.0 7.8 4.8 1 1 4 5 5 5 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 RUS74984.1 - 0.0082 16.7 8.1 0.0082 16.7 8.1 5.1 1 1 4 5 5 4 3 Apg6 coiled-coil region DUF5624 PF18538.1 RUS74984.1 - 0.018 15.2 0.3 0.018 15.2 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5624) Whirly PF08536.11 RUS74984.1 - 0.044 13.6 0.5 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Whirly transcription factor KASH_CCD PF14662.6 RUS74984.1 - 0.8 9.5 61.1 0.3 10.9 18.0 3.3 1 1 2 3 3 2 0 Coiled-coil region of CCDC155 or KASH MbeD_MobD PF04899.12 RUS74984.1 - 1 9.5 22.0 0.11 12.6 3.7 4.1 3 2 1 4 4 4 0 MbeD/MobD like DUF1664 PF07889.12 RUS74984.1 - 2.3 8.3 20.1 0.22 11.6 4.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 RUS74984.1 - 4 7.6 55.2 14 5.8 23.8 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 RUS74984.1 - 4 7.7 8.4 35 4.7 0.3 3.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 RUS74984.1 - 5.8 6.9 25.5 0.48 10.4 1.6 4.2 3 2 3 6 6 6 0 Laminin Domain II ING PF12998.7 RUS74984.1 - 6.4 7.4 22.9 0.54 10.9 2.1 4.0 2 1 3 5 5 5 0 Inhibitor of growth proteins N-terminal histone-binding Cob_adeno_trans PF01923.18 RUS74985.1 - 0.064 13.4 0.1 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase TPR_2 PF07719.17 RUS74985.1 - 0.22 11.7 2.7 4.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fibrinogen_C PF00147.18 RUS74986.1 - 1.1e-57 195.4 0.9 1.6e-57 194.9 0.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS74986.1 - 3.5e-05 23.8 4.5 0.00075 19.4 3.9 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS74986.1 - 9e-05 22.5 4.9 0.25 11.4 0.3 3.4 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 RUS74986.1 - 0.00025 21.3 0.8 0.56 10.5 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF5082) CLZ PF16526.5 RUS74986.1 - 0.0024 18.2 6.5 0.095 13.1 1.6 4.2 2 1 2 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4197 PF13852.6 RUS74986.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) ABC_tran_CTD PF16326.5 RUS74986.1 - 0.029 14.6 2.1 0.48 10.7 1.5 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Phasin PF05597.11 RUS74986.1 - 0.035 14.1 4.5 0.34 10.9 0.9 2.8 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GBP_C PF02841.14 RUS74986.1 - 0.037 13.4 6.9 0.075 12.4 6.3 1.8 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4164 PF13747.6 RUS74986.1 - 0.047 14.0 5.9 2.6 8.4 3.8 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 RUS74986.1 - 0.058 13.4 4.7 0.085 12.9 0.3 2.9 1 1 1 2 2 2 0 Laminin Domain II RRF_GI PF12614.8 RUS74986.1 - 0.059 13.5 2.0 34 4.6 0.0 3.2 2 1 1 3 3 3 0 Ribosome recycling factor DUF3053 PF11254.8 RUS74986.1 - 0.061 12.9 0.6 0.12 11.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) CdvA PF18822.1 RUS74986.1 - 0.16 11.8 4.3 0.63 9.9 2.6 2.6 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 RUS74986.1 - 0.17 11.9 4.9 3.7 7.6 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RUS74986.1 - 0.18 12.0 4.1 1.6 8.9 0.9 2.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Clusterin PF01093.17 RUS74986.1 - 0.2 10.7 8.8 0.13 11.2 2.3 2.1 1 1 1 2 2 2 0 Clusterin BLOC1_2 PF10046.9 RUS74986.1 - 0.26 11.6 3.3 1.2 9.4 0.3 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 RUS74986.1 - 0.27 9.1 3.3 0.35 8.7 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 RUS74986.1 - 0.33 10.5 5.1 2.4 7.7 5.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 RUS74986.1 - 0.51 10.4 4.0 1 9.4 0.2 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding YtxH PF12732.7 RUS74986.1 - 0.52 10.9 5.3 70 4.1 3.3 3.4 2 1 0 2 2 2 0 YtxH-like protein GAS PF13851.6 RUS74986.1 - 0.71 9.2 8.4 1.4 8.3 5.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 RUS74986.1 - 1.2 9.4 5.5 0.35 11.1 1.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TBCC_N PF16752.5 RUS74986.1 - 1.5 9.3 7.2 2.5 8.5 3.4 2.7 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain XhlA PF10779.9 RUS74986.1 - 2.2 8.5 5.1 8 6.8 1.5 2.8 3 0 0 3 3 2 0 Haemolysin XhlA Prominin PF05478.11 RUS74986.1 - 2.4 6.0 5.4 7 4.5 4.9 1.6 1 1 0 1 1 1 0 Prominin CorA PF01544.18 RUS74986.1 - 2.9 7.1 5.4 2.7 7.2 2.0 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Tropomyosin_1 PF12718.7 RUS74986.1 - 3.3 7.8 8.5 4.6 7.4 6.1 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 RUS74986.1 - 4.3 6.9 10.0 34 4.0 8.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 RUS74986.1 - 4.5 7.7 7.2 27 5.3 1.7 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_S30AE PF02482.19 RUS74986.1 - 9.9 7.0 6.7 2.9 8.7 1.1 2.8 3 1 0 3 3 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Fibrinogen_C PF00147.18 RUS74987.1 - 9.9e-57 192.3 0.5 1.6e-56 191.6 0.5 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF5082 PF16888.5 RUS74987.1 - 0.0046 17.2 2.0 0.0071 16.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 RUS74987.1 - 0.006 16.6 12.8 0.41 10.7 5.9 3.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 RUS74987.1 - 0.0089 16.4 2.6 2.2 8.7 1.3 3.6 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 RUS74987.1 - 0.021 15.0 2.1 0.039 14.1 2.1 1.4 1 0 0 1 1 1 0 Tropomyosin like Taxilin PF09728.9 RUS74987.1 - 0.029 13.5 1.6 0.05 12.8 1.6 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Tropomyosin PF00261.20 RUS74987.1 - 0.065 12.6 3.3 0.15 11.4 3.3 1.6 1 1 0 1 1 1 0 Tropomyosin Lectin_N PF03954.14 RUS74987.1 - 0.087 12.6 2.1 0.21 11.3 0.8 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 RUS74987.1 - 0.098 12.7 3.4 1.8 8.6 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4607 PF15380.6 RUS74987.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) ABC_tran_CTD PF16326.5 RUS74987.1 - 0.12 12.6 0.7 0.31 11.3 0.7 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Apolipoprotein PF01442.18 RUS74987.1 - 0.15 11.9 0.1 1.9 8.3 0.2 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CdvA PF18822.1 RUS74987.1 - 0.18 11.6 4.9 0.5 10.2 0.7 2.5 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Fez1 PF06818.15 RUS74987.1 - 0.37 11.2 2.6 1.3 9.5 2.6 1.9 1 1 0 1 1 1 0 Fez1 Phasin PF05597.11 RUS74987.1 - 0.59 10.1 3.5 12 5.9 0.6 2.8 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 RUS74987.1 - 0.89 9.7 8.5 2 8.6 3.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG17 PF04108.12 RUS74987.1 - 1 8.4 9.9 4.1 6.4 9.9 1.9 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF1640 PF07798.11 RUS74987.1 - 1 9.4 9.3 4.4 7.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 RUS74987.1 - 1 9.8 6.0 39 4.7 2.3 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HSBP1 PF06825.12 RUS74987.1 - 2.5 8.0 9.7 0.98 9.3 0.1 3.7 3 1 1 4 4 4 0 Heat shock factor binding protein 1 Mer2 PF09074.10 RUS74987.1 - 2.7 7.8 14.5 1.6 8.5 1.7 2.4 1 1 1 2 2 2 0 Mer2 DUF4795 PF16043.5 RUS74987.1 - 4.9 6.7 8.0 53 3.3 7.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Fzo_mitofusin PF04799.13 RUS74987.1 - 6.2 6.3 6.9 6.1 6.4 1.6 3.0 2 2 2 4 4 4 0 fzo-like conserved region fn3 PF00041.21 RUS74988.1 - 1.3e-156 509.3 37.1 2.9e-15 56.4 0.2 13.5 13 0 0 13 13 13 13 Fibronectin type III domain I-set PF07679.16 RUS74988.1 - 1.7e-64 213.9 0.8 4e-19 68.5 0.0 7.2 8 0 0 8 8 7 5 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS74988.1 - 2.8e-56 188.0 5.7 9.7e-14 51.7 0.0 7.5 8 0 0 8 8 6 5 Immunoglobulin domain Ig_2 PF13895.6 RUS74988.1 - 1e-31 109.0 2.4 5.4e-07 29.9 0.0 6.6 7 0 0 7 7 6 5 Immunoglobulin domain ig PF00047.25 RUS74988.1 - 2.2e-30 104.6 0.0 1.8e-07 31.2 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS74988.1 - 5.9e-22 78.0 21.7 0.0084 16.7 0.0 11.9 14 0 0 14 14 12 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 RUS74988.1 - 1.3e-19 70.4 5.5 0.012 15.8 0.0 9.7 8 3 0 8 8 6 4 Immunoglobulin V-set domain Interfer-bind PF09294.10 RUS74988.1 - 5.9e-11 42.6 0.3 0.055 13.8 0.0 8.1 8 0 0 8 8 7 1 Interferon-alpha/beta receptor, fibronectin type III Ig_6 PF18452.1 RUS74988.1 - 2.3e-09 36.7 0.0 2 8.0 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin domain Ig_4 PF16680.5 RUS74988.1 - 1.4e-07 31.7 0.0 2.1 8.6 0.0 5.5 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Tissue_fac PF01108.17 RUS74988.1 - 7.3e-06 25.8 1.2 1.7 8.6 0.0 6.4 6 1 0 7 7 7 1 Tissue factor Ig_5 PF16681.5 RUS74988.1 - 2.6e-05 24.5 0.0 13 6.3 0.0 4.6 4 0 0 4 4 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 RUS74988.1 - 3.7e-05 23.7 0.0 19 5.4 0.0 5.2 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 RUS74988.1 - 7.1e-05 23.0 0.4 0.68 10.2 0.0 5.4 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 fn3_4 PF16794.5 RUS74988.1 - 0.00012 22.0 0.0 0.13 12.2 0.0 5.0 4 0 0 4 4 4 1 Fibronectin-III type domain C2-set_2 PF08205.12 RUS74988.1 - 0.00019 21.4 0.0 0.34 11.0 0.0 3.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 RUS74988.1 - 0.0002 20.2 0.9 0.23 10.1 0.0 4.6 4 1 1 5 5 5 1 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 RUS74988.1 - 0.01 15.8 0.0 9.8 6.3 0.0 3.0 2 0 0 2 2 2 0 C17orf99 Ig domain Reeler PF02014.16 RUS74988.1 - 0.19 12.5 0.9 74 4.1 0.0 5.0 6 0 0 6 6 6 0 Reeler domain RNase_H PF00075.24 RUS74989.1 - 1.9e-07 31.4 1.3 5.6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 RNase H DUF4864 PF16156.5 RUS74989.1 - 0.042 14.5 0.1 0.097 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) PIN_12 PF16289.5 RUS74990.1 - 1.7 9.2 0.0 1.7 9.2 0.0 2.6 3 0 0 3 3 3 0 PIN domain RVT_1 PF00078.27 RUS74991.1 - 9e-32 110.4 1.6 1.1e-31 110.1 0.2 2.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3932 PF13068.6 RUS74994.1 - 0.00012 22.3 4.8 28 5.1 0.2 7.7 5 3 2 8 8 8 2 Protein of unknown function (DUF3932) DUF2092 PF09865.9 RUS74994.1 - 0.12 11.7 0.0 22 4.3 0.0 3.8 4 1 1 5 5 5 0 Predicted periplasmic protein (DUF2092) zf_ZIC PF18366.1 RUS74995.1 - 1.6e-26 92.1 3.6 1.6e-26 92.1 3.6 3.2 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 RUS74995.1 - 1.7e-16 59.7 29.5 1.1e-05 25.6 0.2 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS74995.1 - 1.2e-15 57.1 33.7 6.1e-07 29.6 0.4 5.6 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS74995.1 - 3.2e-07 30.6 25.8 0.014 16.1 0.2 6.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS74995.1 - 0.082 13.2 10.2 21 5.6 0.4 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS74995.1 - 0.27 11.3 6.9 5.1 7.2 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RUS74995.1 - 0.82 9.8 6.0 23 5.1 0.0 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 RUS74995.1 - 2.6 8.7 12.5 36 5.1 0.0 5.4 2 2 3 5 5 5 0 FOXP coiled-coil domain GDH_N PF12466.8 RUS74997.1 - 0.0088 16.2 0.1 2.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Glutamate dehydrogenase N terminal CBP_CCPA PF17040.5 RUS74997.1 - 0.019 15.5 0.0 7.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Cellulose-complementing protein A RRP36 PF06102.12 RUS74997.1 - 0.06 13.3 0.8 6.2 6.8 0.1 2.2 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF3396 PF11876.8 RUS74997.1 - 0.062 12.8 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3396) SAE2 PF08573.10 RUS74998.1 - 2e-08 35.3 10.8 1.3e-06 29.5 0.5 2.9 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus ADD_ATRX PF17981.1 RUS74998.1 - 0.067 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Cysteine Rich ADD domain DUF5595 PF18077.1 RUS74999.1 - 0.0012 18.8 0.3 0.0012 18.8 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5595) TSC22 PF01166.18 RUS74999.1 - 0.026 14.8 0.4 0.095 13.0 0.4 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF648 PF04890.13 RUS74999.1 - 0.13 12.0 2.3 0.17 11.6 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Tmemb_185A PF10269.9 RUS75000.1 - 4e-14 52.9 5.9 4.7e-14 52.7 5.9 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein PsbJ PF01788.17 RUS75000.1 - 5.7 6.9 7.0 8.1 6.4 0.6 2.5 2 0 0 2 2 2 0 PsbJ NMD3 PF04981.13 RUS75001.1 - 8e-80 267.8 2.5 1.1e-79 267.3 2.5 1.2 1 0 0 1 1 1 1 NMD3 family TOPRIM_C PF16898.5 RUS75001.1 - 0.29 11.4 3.3 0.21 11.9 0.5 2.1 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM DUF1289 PF06945.13 RUS75001.1 - 0.51 10.2 0.0 0.51 10.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) zf-HYPF PF07503.12 RUS75001.1 - 2.7 7.9 10.3 0.78 9.6 1.0 3.2 3 0 0 3 3 3 0 HypF finger EF-hand_7 PF13499.6 RUS75002.1 - 1.6e-18 66.9 0.5 6.2e-08 33.0 0.0 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS75002.1 - 1.6e-18 64.8 0.0 0.00014 21.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RUS75002.1 - 1.6e-18 65.0 0.0 8.6e-05 22.2 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RUS75002.1 - 4.3e-18 63.9 0.1 7.5e-06 25.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RUS75002.1 - 4.9e-09 35.9 0.6 1.1e-05 25.1 0.0 3.0 3 2 0 3 3 3 2 EF-hand domain pair Caleosin PF05042.13 RUS75002.1 - 0.0062 16.5 0.3 0.096 12.6 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein CENP-B_dimeris PF09026.10 RUS75004.1 - 0.00071 19.9 4.3 0.00071 19.9 4.3 3.6 2 1 0 2 2 2 1 Centromere protein B dimerisation domain DUF1676 PF07898.13 RUS75004.1 - 0.036 14.1 0.3 0.036 14.1 0.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) DUF5383 PF17355.2 RUS75004.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5383) Orf78 PF06024.12 RUS75004.1 - 0.66 10.3 0.0 0.66 10.3 0.0 2.9 2 1 0 2 2 2 0 Orf78 (ac78) SID-1_RNA_chan PF13965.6 RUS75004.1 - 1.7 7.0 10.9 2.9 6.2 10.9 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 RIX1 PF08167.12 RUS75005.1 - 0.2 11.4 2.9 1.1 8.9 0.7 3.0 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Urb2 PF10441.9 RUS75006.1 - 1.1e-12 48.4 0.3 1.3e-12 48.1 0.3 1.1 1 0 0 1 1 1 1 Urb2/Npa2 family Glyco_transf_24 PF18404.1 RUS75006.1 - 0.006 16.0 0.0 0.0072 15.8 0.0 1.0 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_22 PF03901.17 RUS75012.1 - 8.6e-35 120.8 11.8 3.2e-27 95.8 7.6 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Pex16 PF08610.10 RUS75012.1 - 0.057 12.6 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Period_C PF12114.8 RUS75012.1 - 0.18 11.4 5.0 0.3 10.6 5.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Acyl-CoA_ox_N PF14749.6 RUS75013.1 - 1.9e-17 64.0 0.0 2.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.16 RUS75013.1 - 0.17 12.6 0.0 2.4 8.9 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain NuDC PF16273.5 RUS75017.1 - 0.012 16.1 1.2 0.012 16.1 1.2 3.9 3 1 1 4 4 2 0 Nuclear distribution C domain DUF2151 PF10221.9 RUS75017.1 - 0.18 10.4 5.9 0.18 10.4 5.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 RUS75017.1 - 0.28 9.9 9.6 0.32 9.7 9.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 RUS75017.1 - 0.4 10.5 13.5 0.59 10.0 13.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 RUS75017.1 - 0.49 9.7 20.7 0.64 9.3 20.7 1.2 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 RUS75017.1 - 0.6 8.8 8.2 0.6 8.8 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RF-1 PF00472.20 RUS75017.1 - 0.75 9.8 10.5 1.8 8.5 10.5 1.6 1 0 0 1 1 1 0 RF-1 domain MIF4G_like_2 PF09090.11 RUS75017.1 - 0.88 9.0 9.6 1.2 8.5 9.6 1.2 1 0 0 1 1 1 0 MIF4G like CDC45 PF02724.14 RUS75017.1 - 1.2 7.3 13.9 1.4 7.2 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 RUS75017.1 - 1.4 7.0 6.8 1.6 6.8 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.10 RUS75017.1 - 1.5 9.1 15.9 2.2 8.5 15.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.19 RUS75017.1 - 1.9 6.3 12.2 2.4 6.0 12.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 RUS75017.1 - 2.4 6.9 9.4 2.7 6.6 9.4 1.1 1 0 0 1 1 1 0 Presenilin Slu7 PF11708.8 RUS75017.1 - 2.7 7.7 18.5 4.2 7.0 18.5 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RR_TM4-6 PF06459.12 RUS75017.1 - 2.9 7.7 15.6 4.2 7.1 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 RUS75017.1 - 2.9 6.0 23.0 3.3 5.8 23.0 1.2 1 0 0 1 1 1 0 Nop14-like family PPL5 PF18168.1 RUS75017.1 - 3.3 6.9 9.1 4.9 6.4 9.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Usp PF00582.26 RUS75017.1 - 3.5 8.1 16.6 62 4.1 16.6 2.2 1 1 0 1 1 1 0 Universal stress protein family MAS20 PF02064.15 RUS75017.1 - 4.6 7.4 15.4 6.9 6.8 15.4 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor CDC27 PF09507.10 RUS75017.1 - 6.8 6.0 24.3 8.7 5.6 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.16 RUS75017.1 - 7.3 5.9 14.8 11 5.3 14.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 F-protein PF00469.20 RUS75017.1 - 9.5 5.7 11.2 2.8 7.5 8.5 1.4 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Fibrinogen_C PF00147.18 RUS75018.1 - 8.6e-56 189.2 0.2 1.3e-55 188.7 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS75018.1 - 0.00028 20.9 9.0 0.018 15.1 4.4 2.9 2 2 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RUS75018.1 - 0.00036 20.6 2.3 0.016 15.3 1.7 2.2 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF5082 PF16888.5 RUS75018.1 - 0.0017 18.6 1.7 0.0017 18.6 1.7 2.5 2 2 1 3 3 3 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 RUS75018.1 - 0.0017 17.3 12.0 0.0024 16.8 11.6 1.3 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4164 PF13747.6 RUS75018.1 - 0.0024 18.1 7.8 0.0024 18.1 7.8 2.6 2 2 2 4 4 2 1 Domain of unknown function (DUF4164) Apolipoprotein PF01442.18 RUS75018.1 - 0.0089 15.9 13.7 0.024 14.5 13.7 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Remorin_C PF03763.13 RUS75018.1 - 0.009 15.9 7.5 0.022 14.6 7.5 1.5 1 1 0 1 1 1 1 Remorin, C-terminal region Fzo_mitofusin PF04799.13 RUS75018.1 - 0.011 15.3 4.6 0.32 10.5 4.2 2.5 2 0 0 2 2 2 0 fzo-like conserved region Syntaxin PF00804.25 RUS75018.1 - 0.013 15.2 3.5 0.026 14.2 3.5 1.4 1 0 0 1 1 1 0 Syntaxin DUF3584 PF12128.8 RUS75018.1 - 0.014 13.0 3.3 0.019 12.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hormone_1 PF00103.20 RUS75018.1 - 0.019 14.7 3.8 0.024 14.4 1.7 1.9 2 0 0 2 2 2 0 Somatotropin hormone family CdvA PF18822.1 RUS75018.1 - 0.021 14.7 2.3 0.021 14.7 2.3 3.2 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Laminin_II PF06009.12 RUS75018.1 - 0.033 14.2 4.7 0.033 14.2 3.1 1.8 2 0 0 2 2 1 0 Laminin Domain II Taxilin PF09728.9 RUS75018.1 - 0.034 13.3 9.0 0.061 12.5 9.0 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GAS PF13851.6 RUS75018.1 - 0.042 13.2 12.0 0.18 11.1 9.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lipoprotein_15 PF03640.15 RUS75018.1 - 0.048 13.2 0.5 0.09 12.3 0.5 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function ApoO PF09769.9 RUS75018.1 - 0.056 13.4 2.3 0.15 12.0 0.3 2.6 2 2 0 3 3 2 0 Apolipoprotein O AAA_13 PF13166.6 RUS75018.1 - 0.057 12.1 4.2 0.075 11.7 4.2 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 RUS75018.1 - 0.075 13.6 9.4 0.15 12.7 5.3 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 RUS75018.1 - 0.096 12.0 4.8 0.15 11.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 RUS75018.1 - 0.11 12.3 10.8 0.22 11.3 10.8 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 RUS75018.1 - 0.13 11.8 8.4 0.19 11.3 8.1 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.11 RUS75018.1 - 0.27 11.3 11.4 0.17 11.9 9.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Tropomyosin_1 PF12718.7 RUS75018.1 - 0.28 11.3 13.8 0.11 12.7 10.4 1.9 2 0 0 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 RUS75018.1 - 0.29 10.7 11.6 5.8 6.5 10.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Prominin PF05478.11 RUS75018.1 - 0.4 8.6 3.0 0.28 9.1 1.0 1.5 2 0 0 2 2 2 0 Prominin DHR10 PF18595.1 RUS75018.1 - 0.44 10.6 12.0 4.2 7.5 12.0 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain WXG100 PF06013.12 RUS75018.1 - 0.46 10.7 5.4 28 5.0 0.3 3.7 2 1 0 3 3 3 0 Proteins of 100 residues with WXG OmpH PF03938.14 RUS75018.1 - 0.56 10.5 9.5 0.17 12.2 6.4 1.7 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) SF-assemblin PF06705.11 RUS75018.1 - 0.62 9.4 10.9 0.64 9.3 6.6 2.4 1 1 0 2 2 2 0 SF-assemblin/beta giardin FH2 PF02181.23 RUS75018.1 - 0.69 9.0 8.2 4.2 6.4 5.2 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Phage_Mu_Gam PF07352.12 RUS75018.1 - 0.73 9.7 7.5 0.65 9.9 3.2 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FAM76 PF16046.5 RUS75018.1 - 0.73 9.1 4.4 1.2 8.5 4.4 1.3 1 0 0 1 1 1 0 FAM76 protein FliD_C PF07195.12 RUS75018.1 - 0.86 9.0 8.9 1.1 8.6 4.7 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus YtxH PF12732.7 RUS75018.1 - 0.99 10.0 9.7 70 4.1 7.2 3.3 2 1 0 2 2 2 0 YtxH-like protein DUF2884 PF11101.8 RUS75018.1 - 1.4 8.4 6.8 7.6 6.0 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) ACCA PF03255.14 RUS75018.1 - 1.5 8.6 5.3 1.2 9.1 3.3 1.8 2 0 0 2 2 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit T3SS_needle_F PF09392.10 RUS75018.1 - 1.8 8.8 3.5 55 4.1 0.0 3.1 2 1 1 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Lectin_N PF03954.14 RUS75018.1 - 2.4 7.9 7.6 1.3 8.8 3.3 2.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain ECM11 PF15463.6 RUS75018.1 - 2.7 8.6 8.7 0.35 11.5 3.1 2.2 2 1 1 3 3 2 0 Extracellular mutant protein 11 NPV_P10 PF05531.12 RUS75018.1 - 2.9 8.4 4.3 12 6.5 3.6 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4618 PF15397.6 RUS75018.1 - 3.2 7.1 9.6 0.48 9.8 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) BshC PF10079.9 RUS75018.1 - 3.3 6.4 6.7 0.85 8.3 3.8 1.4 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF4085 PF13315.6 RUS75018.1 - 3.4 7.3 6.3 1.3 8.6 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Atg14 PF10186.9 RUS75018.1 - 4.8 6.2 8.9 4.4 6.3 7.4 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 RUS75018.1 - 5.8 7.6 9.8 36 5.1 6.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Sugarporin_N PF11471.8 RUS75018.1 - 6.7 6.8 9.4 10 6.2 1.6 3.0 1 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CorA PF01544.18 RUS75018.1 - 7.1 5.9 8.8 1.9 7.7 5.5 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein EMP24_GP25L PF01105.24 RUS75018.1 - 7.2 6.5 5.9 5.6 6.9 3.7 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD H-kinase_dim PF02895.14 RUS75018.1 - 7.6 7.0 6.7 1.2e+03 0.0 6.6 3.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain FadA PF09403.10 RUS75018.1 - 8.2 7.0 13.7 3 8.4 3.4 2.9 2 1 1 3 3 3 0 Adhesion protein FadA DUF1647 PF07801.11 RUS75019.1 - 1.9e-10 40.7 0.0 3.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) GTP-bdg_N PF13167.6 RUS75019.1 - 0.025 15.2 0.0 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal NDK PF00334.19 RUS75020.1 - 1.2e-52 177.5 0.0 1.4e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Slx4 PF09494.10 RUS75021.1 - 4.8e-10 39.2 0.1 1.7e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Slx4 endonuclease BTB PF00651.31 RUS75022.1 - 0.0003 21.0 0.0 0.00082 19.6 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Gp5_C PF06715.12 RUS75022.1 - 0.38 11.0 7.7 12 6.3 0.1 5.1 4 2 2 6 6 6 0 Gp5 C-terminal repeat (3 copies) PRP21_like_P PF12230.8 RUS75023.1 - 0.0028 17.6 0.3 0.0028 17.6 0.3 2.9 1 1 1 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Dicty_REP PF05086.12 RUS75026.1 - 0.00092 17.3 6.9 0.00095 17.3 6.9 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Chlor_dismutase PF06778.12 RUS75026.1 - 0.002 17.7 0.5 0.0027 17.3 0.5 1.0 1 0 0 1 1 1 1 Chlorite dismutase Serinc PF03348.15 RUS75026.1 - 0.0026 16.8 0.8 0.0031 16.5 0.8 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF4834 PF16118.5 RUS75026.1 - 0.0048 17.8 2.2 0.0066 17.4 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Folate_carrier PF01770.18 RUS75026.1 - 0.0051 15.6 1.4 0.0055 15.5 1.4 1.1 1 0 0 1 1 1 1 Reduced folate carrier MMM1 PF10296.9 RUS75026.1 - 0.0054 15.8 1.5 0.0059 15.7 1.5 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 EPL1 PF10513.9 RUS75026.1 - 0.0069 16.8 2.6 0.0072 16.7 2.6 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like CHD5 PF04420.14 RUS75026.1 - 0.032 14.1 0.9 0.039 13.8 0.9 1.2 1 0 0 1 1 1 0 CHD5-like protein RICTOR_N PF14664.6 RUS75026.1 - 0.035 13.1 0.9 0.037 13.0 0.9 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Presenilin PF01080.17 RUS75026.1 - 0.042 12.6 0.2 0.042 12.6 0.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 RUS75026.1 - 0.043 13.2 0.9 0.049 13.0 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltransf_12 PF08242.12 RUS75026.1 - 0.048 14.4 0.4 0.059 14.1 0.4 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4820 PF16091.5 RUS75026.1 - 0.057 12.8 1.5 0.062 12.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Menin PF05053.13 RUS75026.1 - 0.058 11.8 3.2 0.056 11.8 3.2 1.1 1 0 0 1 1 1 0 Menin Pex14_N PF04695.13 RUS75026.1 - 0.072 13.7 3.8 0.078 13.6 3.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4400 PF14348.6 RUS75026.1 - 0.12 11.9 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) HCO3_cotransp PF00955.21 RUS75026.1 - 0.35 9.6 2.8 0.34 9.7 2.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family Tir_receptor_C PF07489.11 RUS75026.1 - 0.45 10.4 11.3 0.56 10.2 11.3 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Spt20 PF12090.8 RUS75026.1 - 2.4 7.7 17.2 3.1 7.4 17.2 1.1 1 0 0 1 1 1 0 Spt20 family Beta-lactamase PF00144.24 RUS75027.1 - 4.9e-33 114.8 0.3 6e-33 114.5 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase zf_C2H2_6 PF18450.1 RUS75028.1 - 0.0088 15.7 22.5 16 5.3 0.2 8.0 1 1 8 9 9 9 8 Zinc Finger domain zf-FCS PF06467.14 RUS75028.1 - 0.41 10.6 17.6 60 3.7 1.2 6.4 1 1 7 8 8 8 0 MYM-type Zinc finger with FCS sequence motif Beta-lactamase PF00144.24 RUS75029.1 - 1.4e-11 44.3 0.9 2e-11 43.7 0.9 1.2 1 0 0 1 1 1 1 Beta-lactamase CDK2AP PF09806.9 RUS75029.1 - 0.013 15.6 6.6 0.015 15.3 6.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 RUS75029.1 - 0.028 13.3 16.0 0.03 13.2 16.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 RUS75029.1 - 0.049 12.2 16.4 0.051 12.1 16.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 RUS75029.1 - 0.052 13.6 18.9 0.093 12.7 18.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PI3K_1B_p101 PF10486.9 RUS75029.1 - 0.24 9.2 12.6 0.28 8.9 12.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NPR3 PF03666.13 RUS75029.1 - 0.3 9.8 8.3 0.36 9.6 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RUS75029.1 - 0.36 9.6 6.5 0.41 9.4 6.5 1.1 1 0 0 1 1 1 0 Presenilin Sec3_C PF09763.9 RUS75029.1 - 0.48 8.8 8.8 0.53 8.6 8.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 NAM-associated PF14303.6 RUS75029.1 - 0.77 10.5 12.7 1.2 9.8 12.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SPX PF03105.19 RUS75029.1 - 1.1 9.0 20.6 1.4 8.7 20.6 1.1 1 0 0 1 1 1 0 SPX domain Cyclin PF08613.11 RUS75029.1 - 1.2 9.5 9.3 2.4 8.5 9.3 1.6 1 0 0 1 1 1 0 Cyclin Miga PF10265.9 RUS75029.1 - 1.9 7.4 9.5 2 7.3 9.5 1.2 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 RUS75029.1 - 3.7 5.7 20.5 4.1 5.6 20.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BORCS6 PF10157.9 RUS75029.1 - 9.8 6.4 13.6 22 5.2 13.6 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Pkinase_Tyr PF07714.17 RUS75032.1 - 4.1e-58 196.7 0.0 6.3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS75032.1 - 1.6e-52 178.5 0.0 2.5e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 RUS75032.1 - 8.7e-17 61.0 0.0 1.8e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 RUS75032.1 - 1.2e-09 37.9 6.4 2.6e-09 36.8 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 RUS75032.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 RUS75032.1 - 0.00079 19.7 8.0 0.0021 18.3 8.0 1.7 1 0 0 1 1 1 1 RING-like domain Kdo PF06293.14 RUS75032.1 - 0.0048 16.3 0.3 0.0098 15.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS75032.1 - 0.0064 15.3 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase HicA_toxin PF07927.12 RUS75032.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, C1_2 PF03107.16 RUS75032.1 - 0.16 12.3 4.0 0.44 10.9 4.0 1.7 1 0 0 1 1 1 0 C1 domain DUF812 PF05667.11 RUS75032.1 - 0.25 10.2 2.1 0.44 9.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PHD PF00628.29 RUS75032.1 - 0.29 11.1 5.6 0.67 9.9 5.6 1.6 1 0 0 1 1 1 0 PHD-finger DIE2_ALG10 PF04922.12 RUS75033.1 - 1.1e-116 390.4 31.1 1.4e-116 390.1 31.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family COX4 PF02936.14 RUS75033.1 - 1.1 9.2 3.4 7.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV NUDIX PF00293.28 RUS75034.1 - 4.5e-11 42.9 0.0 6.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TNF PF00229.18 RUS75035.1 - 4.7e-14 52.4 0.0 7.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF3377 PF11857.8 RUS75035.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Y_phosphatase PF00102.27 RUS75036.1 - 7.2e-74 248.3 0.0 1.5e-73 247.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS75036.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RUS75036.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS75036.1 - 0.0029 17.7 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate RNase_T PF00929.24 RUS75036.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 Exonuclease CAP_N PF01213.19 RUS75036.1 - 3.6 7.0 6.0 0.88 9.0 0.4 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Peptidase_C1 PF00112.23 RUS75038.1 - 2.9e-60 204.1 3.5 4.5e-60 203.4 3.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 RUS75038.1 - 1.3e-37 128.7 1.3 2.9e-37 127.6 1.3 1.6 1 0 0 1 1 1 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 RUS75038.1 - 4.1e-05 23.4 0.0 8.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS75038.1 - 0.26 10.0 2.2 1.1 7.9 0.7 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 RUS75039.1 - 4.7e-59 200.1 3.5 8.5e-59 199.3 3.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 RUS75039.1 - 1.4e-34 118.9 1.1 3.8e-34 117.6 1.1 1.8 1 0 0 1 1 1 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 RUS75039.1 - 5.7e-06 26.1 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS75039.1 - 0.00025 19.9 2.6 0.042 12.6 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family TAL_effector PF03377.13 RUS75039.1 - 0.1 12.9 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 TAL effector repeat Spectrin PF00435.21 RUS75041.1 - 0.0034 17.8 1.2 0.05 14.1 0.6 2.3 2 0 0 2 2 2 1 Spectrin repeat ABC_tran_CTD PF16326.5 RUS75041.1 - 0.013 15.8 3.7 0.037 14.3 1.1 2.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF5471 PF17565.2 RUS75041.1 - 0.097 13.0 0.1 0.39 11.0 0.1 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5471) 7tm_7 PF08395.12 RUS75041.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Lipase PF00151.19 RUS75042.1 - 2e-10 40.5 0.0 2.2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Lipase TRAP_alpha PF03896.16 RUS75042.1 - 0.039 13.2 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIIC_sub6 PF10419.9 RUS75043.1 - 5e-15 55.1 0.1 6.2e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain HECT PF00632.25 RUS75044.1 - 1.7e-92 310.2 0.0 2.7e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 RUS75046.1 - 0.00014 21.4 0.1 0.00033 20.2 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif TAN PF11640.8 RUS75046.1 - 4.4 7.4 5.8 1.6 8.8 0.8 2.6 2 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Claudin_2 PF13903.6 RUS75047.1 - 7.7e-06 25.8 16.4 0.0034 17.1 16.4 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Lig_chan PF00060.26 RUS75047.1 - 0.002 18.0 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Clc-like PF07062.12 RUS75047.1 - 0.056 12.9 13.2 0.11 12.0 0.2 2.3 1 1 1 2 2 2 0 Clc-like GtrA PF04138.14 RUS75047.1 - 2.3 8.5 10.8 0.32 11.3 6.1 1.9 1 1 1 2 2 2 0 GtrA-like protein DUF2516 PF10724.9 RUS75047.1 - 2.3 8.5 5.4 0.47 10.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) IU_nuc_hydro PF01156.19 RUS75048.1 - 1.6e-56 192.2 0.0 2.4e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Integrase_H2C2 PF17921.1 RUS75048.1 - 0.0061 16.6 0.1 0.02 15.0 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zinc-ribbons_6 PF07191.12 RUS75048.1 - 0.22 11.5 2.1 2.1 8.4 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbons zf-C2H2_jaz PF12171.8 RUS75048.1 - 0.45 10.9 3.6 0.88 9.9 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS75048.1 - 1.1 9.9 12.0 0.059 13.8 6.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS75048.1 - 5.6 8.1 10.8 1.2 10.1 5.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Arc_trans_TRASH PF08394.10 RUS75048.1 - 8.4 6.8 6.5 1.5 9.2 0.2 2.8 3 0 0 3 3 3 0 Archaeal TRASH domain HSP20 PF00011.21 RUS75049.1 - 4.1e-19 68.6 0.6 5e-19 68.3 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RUS75049.1 - 0.0065 17.5 0.6 0.01 16.9 0.2 1.5 2 0 0 2 2 2 1 CS domain ArsA_HSP20 PF17886.1 RUS75049.1 - 0.0066 16.0 0.0 0.019 14.5 0.0 1.7 2 1 0 2 2 2 1 HSP20-like domain found in ArsA Cadherin_pro PF08758.11 RUS75049.1 - 0.054 13.7 0.1 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 Cadherin prodomain like Flg_hook PF02120.16 RUS75049.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Sulfotransfer_1 PF00685.27 RUS75050.1 - 4.6e-45 154.2 4.7 2.7e-44 151.7 4.7 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS75050.1 - 1e-08 35.9 0.1 9.5e-08 32.7 0.1 2.0 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS75052.1 - 2.7e-25 89.4 0.3 2.2e-24 86.4 0.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain 7tm_1 PF00001.21 RUS75053.1 - 3.2e-09 36.5 2.3 3.8e-09 36.2 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS75053.1 - 0.00018 21.3 12.2 0.00028 20.6 12.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RNA_pol_3_Rpc31 PF11705.8 RUS75053.1 - 0.0092 16.3 9.7 0.015 15.6 9.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RUS75053.1 - 0.011 15.0 4.8 0.018 14.4 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 RUS75053.1 - 0.058 12.4 13.7 0.081 11.9 13.7 1.3 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 RUS75053.1 - 0.13 12.1 10.5 0.28 11.1 10.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 RUS75053.1 - 0.81 9.0 10.8 1.3 8.4 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Voldacs PF03517.13 RUS75053.1 - 1.4 9.1 9.9 2.8 8.1 9.9 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling GRP PF07172.11 RUS75053.1 - 1.7 9.4 4.7 2.1 9.1 3.0 2.1 2 0 0 2 2 1 0 Glycine rich protein family UPF0239 PF06783.11 RUS75053.1 - 2.3 8.4 6.7 2.7 8.2 1.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) CDC45 PF02724.14 RUS75053.1 - 2.7 6.2 10.1 4.8 5.3 10.1 1.4 1 0 0 1 1 1 0 CDC45-like protein 7TM_GPCR_Srw PF10324.9 RUS75053.1 - 3 7.1 12.9 1.3 8.2 10.5 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw TFB6 PF17110.5 RUS75053.1 - 3 7.6 4.9 6.2 6.5 4.9 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 RUS75053.1 - 4.1 6.5 8.0 18 4.4 8.0 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Hamartin PF04388.12 RUS75053.1 - 9 4.8 16.2 12 4.4 16.2 1.1 1 0 0 1 1 1 0 Hamartin protein DNA_pol_phi PF04931.13 RUS75053.1 - 9.6 4.2 17.5 13 3.7 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi IMCp PF12314.8 RUS75054.1 - 0.56 10.5 6.7 0.9 9.9 6.7 1.3 1 0 0 1 1 1 0 Inner membrane complex protein Nuc_deoxyrib_tr PF05014.15 RUS75054.1 - 4.4 7.3 28.2 16 5.5 2.1 5.1 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase zf-MYND PF01753.18 RUS75055.1 - 2.4e-05 24.3 11.3 2.4e-05 24.3 11.3 1.9 2 0 0 2 2 2 1 MYND finger BRF1 PF07741.13 RUS75055.1 - 0.18 12.2 3.5 0.37 11.1 3.5 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FancD2 PF14631.6 RUS75055.1 - 1.9 5.8 6.5 2.7 5.3 6.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SRP-alpha_N PF04086.13 RUS75055.1 - 7.9 6.3 14.6 12 5.8 14.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Trypsin PF00089.26 RUS75056.1 - 5.3e-44 150.7 0.0 5.3e-44 150.7 0.0 1.9 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 RUS75056.1 - 1.1e-33 115.8 0.0 3.2e-14 53.2 0.0 4.8 4 0 0 4 4 4 2 CUB domain MAM PF00629.23 RUS75056.1 - 4.5e-20 72.2 0.8 1.6e-12 47.7 0.4 3.9 2 1 1 3 3 3 3 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 RUS75056.1 - 3.4e-08 33.6 10.3 3.4e-08 33.6 10.3 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A zf-C2H2 PF00096.26 RUS75057.1 - 1.2e-05 25.5 9.1 33 5.2 0.0 6.5 6 1 0 6 6 6 0 Zinc finger, C2H2 type YWFCY PF14293.6 RUS75057.1 - 0.11 12.8 22.8 2.3 8.6 2.0 3.8 1 1 3 4 4 4 0 YWFCY protein XPA_N PF01286.18 RUS75057.1 - 0.15 12.1 10.6 1e+02 3.1 0.0 5.9 4 3 3 7 7 7 0 XPA protein N-terminal zf-FLZ PF04570.14 RUS75057.1 - 1.1 8.8 7.7 26 4.4 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-C2H2_jaz PF12171.8 RUS75057.1 - 1.8 8.9 25.2 15 6.0 0.1 6.9 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Thoc2 PF11732.8 RUS75057.1 - 1.9 8.6 11.1 5.7 7.1 0.7 3.1 2 2 2 4 4 4 0 Transcription- and export-related complex subunit DUF3397 PF11877.8 RUS75057.1 - 3.6 7.8 23.4 8.8 6.6 4.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3397) ANF_receptor PF01094.28 RUS75058.1 - 8.5e-64 215.9 6.8 9.2e-26 90.8 0.3 3.5 3 1 0 3 3 3 3 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS75058.1 - 8.3e-15 55.3 1.7 2e-08 34.3 0.1 4.0 5 0 0 5 5 5 3 Periplasmic binding protein MULE PF10551.9 RUS75059.1 - 1.2e-10 41.6 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain SAPS PF04499.15 RUS75060.1 - 0.72 8.6 10.9 0.84 8.3 10.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4713 PF15831.5 RUS75062.1 - 0.00098 19.5 7.7 3.1e+02 1.9 0.0 9.2 1 1 12 13 13 13 0 Domain of unknown function (DUF4713) zf-RING_2 PF13639.6 RUS75063.1 - 4.8e-10 39.6 11.7 4.8e-10 39.6 11.7 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS75063.1 - 8.6e-07 28.7 10.7 2.1e-06 27.4 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS75063.1 - 2.2e-05 24.6 12.0 2.2e-05 24.6 12.0 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RUS75063.1 - 8.3e-05 22.2 9.2 8.3e-05 22.2 9.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 RUS75063.1 - 0.00032 20.5 10.4 0.00032 20.5 10.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS75063.1 - 0.00038 20.5 5.5 0.00038 20.5 5.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RUS75063.1 - 0.00073 19.5 7.3 0.00086 19.3 5.4 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS75063.1 - 0.011 15.7 10.5 0.011 15.7 10.5 2.0 2 0 0 2 2 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS75063.1 - 0.016 15.0 13.2 0.016 15.0 13.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 RUS75063.1 - 0.22 11.4 7.5 0.49 10.3 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf_Rg PF17915.1 RUS75063.1 - 6.6 6.2 11.4 0.2 11.1 3.9 2.3 3 0 0 3 3 3 0 Reverse gyrase zinc finger Ribosomal_L23 PF00276.20 RUS75064.1 - 6.7e-07 29.6 30.1 0.65 10.4 4.9 6.5 1 1 5 6 6 6 6 Ribosomal protein L23 LBR_tudor PF09465.10 RUS75064.1 - 0.73 9.7 33.4 17 5.3 0.3 7.3 1 1 7 9 9 9 0 Lamin-B receptor of TUDOR domain DUF1115 PF06544.12 RUS75064.1 - 5.3 7.1 10.9 60 3.7 0.1 4.5 1 1 6 7 7 7 0 Protein of unknown function (DUF1115) DUF3709 PF12493.8 RUS75065.1 - 0.5 10.4 20.4 25 5.0 0.3 5.8 1 1 6 7 7 7 0 Protein of unknown function (DUF3709) Toast_rack_N PF17115.5 RUS75067.1 - 0.42 10.9 10.5 66 3.9 0.1 5.8 1 1 8 9 9 9 0 N-terminal domain of toast_rack, DUF2154 NST1 PF13945.6 RUS75068.1 - 0.0019 18.3 2.4 0.0019 18.3 2.4 2.2 1 1 1 2 2 2 1 Salt tolerance down-regulator Velvet PF11754.8 RUS75068.1 - 0.043 13.8 10.5 0.061 13.3 10.5 1.3 1 0 0 1 1 1 0 Velvet factor SelP_N PF04592.14 RUS75068.1 - 0.25 10.7 45.6 0.69 9.3 45.6 1.7 1 1 0 1 1 1 0 Selenoprotein P, N terminal region ALMT PF11744.8 RUS75068.1 - 0.34 9.7 7.0 0.42 9.4 7.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 RUS75068.1 - 0.38 9.5 8.1 0.47 9.2 8.1 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 RUS75068.1 - 1.4 7.0 12.9 1.6 6.9 12.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 RUS75068.1 - 1.7 9.0 10.6 0.61 10.5 8.1 1.6 2 0 0 2 2 2 0 Enhancer of polycomb-like SPX PF03105.19 RUS75068.1 - 2.3 8.1 14.1 2.9 7.7 14.1 1.2 1 0 0 1 1 1 0 SPX domain Spem1 PF15670.5 RUS75068.1 - 4.3 6.8 19.4 9.2 5.8 19.4 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 SLT PF01464.20 RUS75069.1 - 0.0021 17.7 0.1 0.027 14.1 0.1 2.0 1 1 0 1 1 1 1 Transglycosylase SLT domain Stress-antifung PF01657.17 RUS75069.1 - 0.0024 18.5 0.3 0.006 17.2 0.3 1.6 2 0 0 2 2 2 1 Salt stress response/antifungal PorA PF11271.8 RUS75070.1 - 0.16 11.3 11.2 0.22 10.8 11.2 1.2 1 0 0 1 1 1 0 Porin PorA Nop14 PF04147.12 RUS75072.1 - 5.8e-05 21.5 29.2 5.8e-05 21.5 29.2 2.0 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 RUS75072.1 - 0.0029 17.1 31.5 0.0029 17.1 31.5 2.2 2 0 0 2 2 2 1 SDA1 Transposase_1 PF01359.18 RUS75072.1 - 0.015 15.1 0.6 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Transposase (partial DDE domain) CDC45 PF02724.14 RUS75072.1 - 0.12 10.6 29.8 0.015 13.6 23.0 2.1 2 0 0 2 2 2 0 CDC45-like protein NPR3 PF03666.13 RUS75072.1 - 3.5 6.3 6.5 5.3 5.7 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 RUS75072.1 - 7.5 4.9 31.8 0.26 9.7 24.1 1.9 2 0 0 2 2 2 0 Mpp10 protein Shisa PF13908.6 RUS75073.1 - 0.037 14.3 4.0 0.053 13.8 4.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5305 PF17231.2 RUS75073.1 - 0.047 13.1 2.8 0.062 12.7 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 RUS75073.1 - 0.12 12.2 9.1 0.17 11.8 9.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 RUS75073.1 - 0.34 9.6 5.9 0.38 9.5 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DAG1 PF05454.11 RUS75073.1 - 0.41 10.0 3.7 0.45 9.9 3.7 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MMPL PF03176.15 RUS75073.1 - 1.6 7.6 6.7 2.2 7.1 6.7 1.1 1 0 0 1 1 1 0 MMPL family Stevor PF17410.2 RUS75073.1 - 1.9 8.0 8.2 2.3 7.7 8.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4220 PF13968.6 RUS75073.1 - 3.3 7.0 6.4 3.8 6.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3827 PF12877.7 RUS75073.1 - 8.3 4.7 6.5 9.6 4.4 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4481 PF14800.6 RUS75074.1 - 0.0017 17.9 0.2 0.002 17.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) Galactosyl_T PF01762.21 RUS75075.1 - 1.4e-33 116.4 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS75075.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 RUS75076.1 - 4.5e-33 114.7 0.0 6.5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 RUS75077.1 - 1.7e-28 99.8 0.0 2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Pkinase_Tyr PF07714.17 RUS75078.1 - 1.7e-87 293.0 0.0 2.4e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS75078.1 - 1.2e-46 159.3 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS75078.1 - 1.1e-33 115.1 0.0 4.2e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 RUS75078.1 - 0.17 10.8 0.2 0.27 10.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Steroid_dh PF02544.16 RUS75079.1 - 4.3e-38 130.7 6.2 4.3e-38 130.7 6.2 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RUS75079.1 - 1.4e-09 38.3 1.7 1.4e-09 38.3 1.7 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 RUS75079.1 - 2.1e-06 27.4 3.2 2.1e-06 27.4 3.2 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF3188 PF11384.8 RUS75079.1 - 0.71 9.6 0.0 0.71 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF5572 PF17733.1 RUS75080.1 - 6.1e-06 26.0 0.6 1.4e-05 24.8 0.6 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) RPOL_N PF14700.6 RUS75081.1 - 5.6 6.3 8.3 0.2 11.0 1.3 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF4746 PF15928.5 RUS75081.1 - 8.6 5.7 12.1 33 3.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4746) Hemopexin PF00045.19 RUS75082.1 - 1.5e-26 92.0 20.8 1.2e-08 34.8 2.3 5.6 3 1 1 4 4 4 4 Hemopexin Peptidase_M10 PF00413.24 RUS75082.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin Glyco_transf_11 PF01531.16 RUS75084.1 - 3.1e-27 95.6 0.0 3.5e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 11 Peptidase_S24 PF00717.23 RUS75084.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase S24-like DUF4889 PF16230.5 RUS75084.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) FCP1_C PF09309.10 RUS75084.1 - 0.24 11.3 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal SipA_VBS PF17985.1 RUS75087.1 - 0.0026 17.5 0.2 0.0066 16.3 0.1 1.7 2 0 0 2 2 2 1 SipA vinculin binding site FH2 PF02181.23 RUS75088.1 - 2.9e-98 329.4 8.4 2.9e-98 329.4 8.4 2.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RUS75088.1 - 7.5e-38 130.1 12.7 7.5e-38 130.1 12.7 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RUS75088.1 - 2.8e-18 66.2 5.4 2.8e-18 66.2 5.4 3.7 4 1 0 4 4 4 1 Diaphanous GTPase-binding Domain HMMR_N PF15905.5 RUS75088.1 - 0.0032 17.0 10.3 0.0032 17.0 10.3 3.0 3 1 1 4 4 4 1 Hyaluronan mediated motility receptor N-terminal COMP PF11598.8 RUS75088.1 - 0.015 15.8 0.7 0.015 15.8 0.7 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DivIC PF04977.15 RUS75088.1 - 0.44 10.3 17.4 1 9.1 4.0 3.1 2 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 RUS75088.1 - 0.7 10.0 24.4 0.11 12.6 17.0 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Mt_ATP-synt_D PF05873.12 RUS75088.1 - 1.8 8.4 9.3 0.17 11.7 1.4 2.9 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Atg14 PF10186.9 RUS75088.1 - 8 5.4 16.2 0.78 8.8 3.8 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 RUS75088.1 - 8.3 5.9 12.4 4.4 6.8 6.0 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Aldedh PF00171.22 RUS75089.1 - 7.9e-170 565.3 0.0 9.8e-170 565.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RUS75089.1 - 0.032 13.7 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) R3H PF01424.22 RUS75090.1 - 4.1e-16 58.7 0.2 8.3e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 RUS75090.1 - 1.2e-08 34.9 33.2 1.2e-05 25.3 12.5 14.0 14 1 0 14 14 14 7 NF-X1 type zinc finger BORCS8 PF10167.9 RUS75091.1 - 8e-43 144.9 3.8 1.2e-42 144.4 3.8 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 WD40 PF00400.32 RUS75092.1 - 2.8e-36 122.9 15.0 1.5e-05 25.7 0.0 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75092.1 - 4.8e-18 65.2 3.5 2.8e-05 24.3 0.1 6.8 5 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS75092.1 - 2.4e-08 34.1 1.9 0.12 12.2 0.0 4.1 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 RUS75092.1 - 0.0036 17.3 0.1 0.057 13.5 0.1 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DPPIV_N PF00930.21 RUS75092.1 - 0.0084 14.9 2.6 3 6.5 0.2 3.4 3 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_3 PF13570.6 RUS75092.1 - 0.0085 16.6 1.1 13 6.4 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain DUF3319 PF11782.8 RUS75092.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) ENTH PF01417.20 RUS75093.1 - 1.8e-45 154.0 0.1 3.2e-45 153.2 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 RUS75093.1 - 4.9e-06 25.7 0.1 8.4e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 ANTH domain SSF PF00474.17 RUS75094.1 - 1.6e-22 80.0 16.9 3.4e-22 78.9 16.9 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family MFS_2 PF13347.6 RUS75095.1 - 1e-17 63.8 18.9 1.1e-16 60.4 18.9 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein Neur_chan_LBD PF02931.23 RUS75096.1 - 1.5e-70 237.0 2.6 2e-70 236.6 2.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS75096.1 - 3.1e-43 148.5 0.1 4.9e-43 147.9 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HEAT_2 PF13646.6 RUS75097.1 - 5e-06 26.8 0.7 0.0047 17.3 0.1 2.2 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 RUS75097.1 - 0.00035 20.6 0.9 2.5 8.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat API5 PF05918.11 RUS75097.1 - 0.0042 16.0 3.4 0.8 8.4 0.6 2.1 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.7 RUS75097.1 - 0.053 13.6 0.3 0.66 10.0 0.1 2.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 RUS75097.1 - 0.14 12.2 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 V-ATPase subunit H FUSC PF04632.12 RUS75097.1 - 0.34 9.4 2.6 1.1 7.7 2.5 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family BRICHOS PF04089.14 RUS75098.1 - 0.0016 18.7 0.2 0.0039 17.4 0.2 1.8 1 1 0 1 1 1 1 BRICHOS domain Glycos_transf_3 PF00591.21 RUS75099.1 - 7.5e-32 110.9 0.5 1.1e-31 110.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 RUS75099.1 - 3.1e-15 55.8 0.0 6.4e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 RUS75099.1 - 8.2e-15 54.2 0.0 3.1e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain RRM_1 PF00076.22 RUS75101.1 - 5.9e-08 32.4 0.0 0.00061 19.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ST7 PF04184.12 RUS75101.1 - 0.063 11.7 0.0 0.099 11.1 0.0 1.2 1 0 0 1 1 1 0 ST7 protein Presenilin PF01080.17 RUS75101.1 - 0.15 10.8 4.1 0.24 10.1 4.1 1.4 1 0 0 1 1 1 0 Presenilin Tom5 PF10642.9 RUS75101.1 - 0.22 11.6 0.3 0.78 9.8 0.3 2.0 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase ORC_WH_C PF18137.1 RUS75101.1 - 2.8 8.0 14.8 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Vg_Tdu PF07545.14 RUS75103.1 - 2e-14 53.0 0.2 4.4e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Vestigial/Tondu family DUF802 PF05650.11 RUS75107.1 - 0.045 14.2 2.3 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Vg_Tdu PF07545.14 RUS75108.1 - 1.5e-07 31.0 0.2 3.6e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 Vestigial/Tondu family Tti2 PF10521.9 RUS75109.1 - 9.1e-13 48.4 3.2 1.8e-12 47.4 2.1 2.0 2 1 0 2 2 2 1 Tti2 family Ly49 PF08391.10 RUS75109.1 - 0.035 14.5 0.1 0.13 12.6 0.1 2.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Vac14_Fab1_bd PF12755.7 RUS75109.1 - 0.13 12.9 0.1 3.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 RUS75109.1 - 0.14 12.3 0.5 2.8 8.2 0.0 2.7 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Innexin PF00876.18 RUS75110.1 - 6.8e-11 42.1 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Innexin Lectin_C PF00059.21 RUS75111.1 - 5.9e-31 107.4 3.0 2.7e-19 69.9 0.1 2.1 2 0 0 2 2 2 2 Lectin C-type domain Chordopox_A33R PF05966.12 RUS75111.1 - 0.0021 17.4 1.2 0.31 10.3 0.2 2.2 2 0 0 2 2 2 2 Chordopoxvirus A33R protein UL45 PF05473.12 RUS75111.1 - 0.0056 16.4 0.7 0.14 11.8 0.3 2.3 2 1 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Laminin_EGF PF00053.24 RUS75112.1 - 0.027 14.6 38.1 0.5 10.5 18.1 3.5 1 1 2 3 3 3 0 Laminin EGF domain GST_N_4 PF17172.4 RUS75113.1 - 6.6e-23 81.3 0.0 9.1e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS75113.1 - 4.7e-14 51.9 0.0 8.1e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS75113.1 - 2.3e-07 30.7 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS75113.1 - 0.009 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS75113.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1899 PF08953.11 RUS75114.1 - 3.5e-26 90.8 0.1 3.5e-26 90.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 RUS75114.1 - 1.1e-18 66.8 0.3 2.9e-18 65.5 0.1 1.8 2 0 0 2 2 2 1 Type of WD40 repeat Nop14 PF04147.12 RUS75115.1 - 0.00037 18.9 23.1 0.00037 18.9 23.1 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 RUS75115.1 - 0.0029 17.7 32.1 0.0038 17.3 32.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 RUS75115.1 - 0.026 14.4 7.8 0.034 14.0 7.8 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CtnDOT_TraJ PF07863.11 RUS75115.1 - 0.03 15.0 1.9 36 5.1 0.0 4.0 4 1 0 4 4 4 0 Homologues of TraJ from Bacteroides conjugative transposon Vfa1 PF08432.10 RUS75115.1 - 1 9.7 7.5 1.8 8.9 6.9 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 RUS75115.1 - 2 7.1 11.2 2.1 7.0 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RUS75115.1 - 2 6.6 27.3 2.9 6.1 27.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 RUS75115.1 - 9.4 6.2 32.0 16 5.4 32.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_C2 PF00648.21 RUS75116.1 - 3.7e-72 242.9 0.0 3.7e-72 242.9 0.0 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS75116.1 - 2.2e-24 86.3 0.1 3.5e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 RUS75117.1 - 0.061 13.6 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 C2 domain HMG_box PF00505.19 RUS75118.1 - 8.4e-18 64.6 2.0 8.6e-18 64.5 0.5 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS75118.1 - 6e-10 39.6 0.9 6e-10 39.6 0.9 2.0 3 0 0 3 3 3 1 HMG-box domain DUF3450 PF11932.8 RUS75118.1 - 0.00063 19.1 0.9 0.00063 19.1 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF812 PF05667.11 RUS75118.1 - 0.0014 17.6 3.9 0.0018 17.3 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF2353 PF09789.9 RUS75118.1 - 0.0026 17.2 3.9 0.0045 16.4 3.9 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF4763 PF15960.5 RUS75118.1 - 0.0027 17.1 6.2 0.0059 16.0 6.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) LMBR1 PF04791.16 RUS75118.1 - 0.066 12.1 0.5 0.086 11.7 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 RUS75118.1 - 2.7 8.7 10.4 0.19 12.4 3.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TMCO5 PF14992.6 RUS75118.1 - 5.6 6.5 10.6 0.15 11.6 3.7 1.8 2 0 0 2 2 2 0 TMCO5 family APG6_N PF17675.1 RUS75118.1 - 5.7 7.5 18.4 22 5.6 17.7 2.2 2 1 0 2 2 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 RUS75118.1 - 8 6.7 17.5 0.13 12.4 7.3 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 VWC PF00093.18 RUS75121.1 - 0.0016 18.7 0.5 0.24 11.8 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain LUC7 PF03194.15 RUS75122.1 - 0.67 9.6 5.4 2.5 7.7 0.5 3.0 2 1 0 3 3 3 0 LUC7 N_terminus Cys_Met_Meta_PP PF01053.20 RUS75123.1 - 7.3e-114 380.3 0.0 5.3e-76 255.6 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RUS75123.1 - 0.00015 21.1 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RUS75123.1 - 0.0064 15.9 0.0 0.057 12.7 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Eaf7 PF07904.13 RUS75124.1 - 6.7e-14 52.2 0.2 1.4e-13 51.1 0.1 1.7 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 SRP-alpha_N PF04086.13 RUS75124.1 - 4 7.3 9.1 5.8 6.8 9.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ArfGap PF01412.18 RUS75126.1 - 3.6e-39 133.5 0.0 4.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RC-P840_PscD PF10657.9 RUS75126.1 - 0.056 13.6 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD Tocopherol_cycl PF14249.6 RUS75128.1 - 1.1e-07 31.4 1.7 0.015 14.5 0.0 2.9 2 1 0 2 2 2 2 Tocopherol cyclase HMG_box PF00505.19 RUS75129.1 - 7.6e-25 87.1 1.4 1.7e-24 86.0 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS75129.1 - 2.3e-09 37.7 0.2 5.3e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain S4 PF01479.25 RUS75130.1 - 0.00044 19.9 0.0 0.0013 18.4 0.0 1.8 1 1 1 2 2 2 1 S4 domain Mtp PF03821.16 RUS75131.1 - 4.2e-17 62.5 7.4 1.3e-08 34.8 1.6 2.2 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 RUS75131.1 - 0.00033 21.3 2.0 0.00033 21.3 2.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4728) TraE PF05309.11 RUS75131.1 - 0.21 10.9 0.2 0.47 9.8 0.0 1.6 2 0 0 2 2 2 0 TraE protein UNC-50 PF05216.13 RUS75131.1 - 0.43 10.1 9.7 0.072 12.7 4.8 2.2 2 1 0 2 2 2 0 UNC-50 family BRCT PF00533.26 RUS75132.1 - 1.2e-17 64.0 0.3 8.3e-06 26.1 0.0 4.3 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS75132.1 - 5e-15 55.7 0.0 3.1e-06 27.5 0.0 3.6 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 RUS75132.1 - 2.5e-12 46.5 0.4 6.1e-11 42.1 0.1 2.5 2 0 0 2 2 2 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 RUS75132.1 - 1.1e-06 28.4 0.0 0.00012 21.9 0.0 3.1 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RUS75132.1 - 0.0028 17.9 1.4 0.01 16.1 0.1 2.4 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 RUS75132.1 - 0.033 14.3 1.1 21 5.3 0.1 3.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain ISET-FN3_linker PF16625.5 RUS75132.1 - 0.12 12.9 1.2 1.9 9.1 0.4 3.0 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO 7tm_1 PF00001.21 RUS75133.1 - 2.7e-42 144.9 15.5 3.5e-42 144.5 15.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS75133.1 - 7.6e-09 35.6 13.1 7.6e-09 35.6 13.1 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS75133.1 - 2.9e-05 23.6 11.2 0.00021 20.7 8.3 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zf-WRNIP1_ubi PF18279.1 RUS75134.1 - 0.043 14.4 4.3 1.2e+02 3.7 0.0 4.5 4 0 0 4 4 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Fanconi_C PF02106.15 RUS75134.1 - 3.6 6.2 6.3 7.7 5.1 0.6 2.0 1 1 1 2 2 2 0 Fanconi anaemia group C protein RPA_C PF08784.11 RUS75135.1 - 5.6e-15 55.9 3.2 1.7e-14 54.3 0.2 2.6 2 1 1 3 3 3 1 Replication protein A C terminal STN1_2 PF09170.10 RUS75135.1 - 0.00015 22.1 0.6 0.29 11.3 0.0 2.6 1 1 1 2 2 2 2 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 RUS75135.1 - 0.00065 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain P_C PF06640.11 RUS75135.1 - 0.057 13.6 0.2 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 P protein C-terminus WD40 PF00400.32 RUS75137.1 - 6.4e-15 55.3 15.8 4.6e-05 24.1 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75137.1 - 2.5e-05 24.5 0.1 5 7.5 0.0 5.0 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peroxin-3 PF04882.12 RUS75138.1 - 8.7e-54 183.3 1.6 2.6e-26 92.7 0.0 3.0 2 1 1 3 3 3 3 Peroxin-3 SGL PF08450.12 RUS75139.1 - 4.8e-74 249.0 0.5 5.5e-74 248.8 0.5 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RUS75139.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NHL repeat Reg_prop PF07494.11 RUS75139.1 - 0.045 14.0 0.1 2.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Two component regulator propeller Ank_4 PF13637.6 RUS75140.1 - 3e-17 62.7 0.3 4e-09 36.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75140.1 - 4.6e-13 49.6 0.0 5.1e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS75140.1 - 3.4e-09 36.2 0.0 0.00011 22.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS75140.1 - 1.2e-08 35.0 0.0 8.4e-07 29.2 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS75140.1 - 4.2e-08 33.3 0.2 2.9e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat DUF4158 PF13700.6 RUS75140.1 - 0.22 11.4 0.0 0.23 11.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Alpha_kinase PF02816.18 RUS75141.1 - 1.3e-21 77.6 1.8 1.3e-21 77.6 1.8 1.6 2 0 0 2 2 2 1 Alpha-kinase family DUF5422 PF17459.2 RUS75142.1 - 0.0013 18.9 7.5 0.25 11.5 1.5 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5422) DAN PF03045.15 RUS75143.1 - 1.5e-07 31.5 6.3 1.7e-07 31.2 6.3 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 RUS75143.1 - 1.1e-06 28.9 10.1 1.5e-06 28.5 10.1 1.2 1 0 0 1 1 1 1 Cystine-knot domain I-set PF07679.16 RUS75143.1 - 0.015 15.3 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Sugar_tr PF00083.24 RUS75144.1 - 2.4e-73 247.5 14.0 3e-73 247.2 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS75144.1 - 2.4e-23 82.6 18.0 3e-23 82.3 18.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 RUS75144.1 - 0.00068 18.7 3.0 0.00098 18.1 3.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 RUS75144.1 - 1.2 9.7 10.0 0.21 12.2 3.8 2.5 2 0 0 2 2 2 0 Phage holin family 2 DUF2157 PF09925.9 RUS75144.1 - 3 7.6 15.8 0.83 9.4 0.7 3.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) Sugar_tr PF00083.24 RUS75145.1 - 7.4e-20 71.2 4.1 7.4e-20 71.2 4.1 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter Forkhead PF00250.18 RUS75147.1 - 8.1e-39 131.8 0.2 3.8e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 Forkhead domain DUF3439 PF11921.8 RUS75147.1 - 0.036 14.0 5.6 0.073 13.0 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UPF0688 PF15772.5 RUS75147.1 - 1.3 9.2 13.2 2.3 8.4 13.2 1.3 1 0 0 1 1 1 0 UPF0688 family Presenilin PF01080.17 RUS75148.1 - 9.7 4.8 5.9 11 4.6 5.9 1.2 1 0 0 1 1 1 0 Presenilin PAN_1 PF00024.26 RUS75149.1 - 0.00013 21.8 0.9 0.00035 20.5 0.3 1.8 2 0 0 2 2 2 1 PAN domain PH PF00169.29 RUS75150.1 - 2.9e-05 24.5 1.2 9.8e-05 22.8 1.2 1.8 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS75150.1 - 0.24 11.9 2.4 1.2 9.6 2.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain eIF-3_zeta PF05091.12 RUS75150.1 - 1.4 7.8 4.0 1.9 7.4 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Trypan_PARP PF05887.11 RUS75151.1 - 3.5e-07 30.3 97.4 0.0016 18.4 33.0 3.0 1 1 2 3 3 3 3 Procyclic acidic repetitive protein (PARP) Guanylate_cyc PF00211.20 RUS75152.1 - 7.7e-48 162.5 0.0 1.2e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 RUS75152.1 - 1.5e-08 35.4 0.3 3.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Nitrate and nitrite sensing CDC45 PF02724.14 RUS75152.1 - 0.0011 17.3 10.7 0.0016 16.9 10.7 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 RUS75152.1 - 0.0039 15.4 15.7 0.0057 14.8 15.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi eIF-3c_N PF05470.12 RUS75152.1 - 0.047 12.0 0.1 0.062 11.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RXT2_N PF08595.11 RUS75152.1 - 0.16 12.0 7.6 0.29 11.1 7.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal IFT57 PF10498.9 RUS75152.1 - 0.44 9.4 2.3 0.72 8.8 2.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SGT1 PF07093.11 RUS75152.1 - 0.77 8.1 8.0 1.1 7.7 8.0 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 RUS75152.1 - 0.97 7.6 12.8 1.4 7.1 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 RUS75152.1 - 1.2 8.2 30.2 1.8 7.6 30.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 RUS75152.1 - 4.1 6.6 28.8 6.1 6.1 28.8 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 RUS75152.1 - 4.8 6.8 7.3 11 5.7 7.3 1.6 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.13 RUS75152.1 - 6.3 6.7 13.4 9 6.2 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 RUS75152.1 - 7.1 6.8 17.5 10 6.3 17.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 RUS75152.1 - 10 5.8 24.5 20 4.8 24.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Galactosyl_T PF01762.21 RUS75153.1 - 1.4e-34 119.7 0.0 1.8e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase tRNA_m1G_MT PF01746.21 RUS75153.1 - 0.051 13.3 0.4 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase DUF3240 PF11582.8 RUS75153.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Glyco_hydro_79n PF03662.14 RUS75154.1 - 5e-15 55.3 0.0 1e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain BAAT_C PF08840.11 RUS75155.1 - 1.1e-36 126.7 0.0 1.6e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 RUS75155.1 - 2.6e-31 108.3 0.0 3.7e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 RUS75155.1 - 7.2e-05 22.4 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Arm PF00514.23 RUS75157.1 - 5.6e-75 245.3 12.1 2.8e-11 43.0 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RUS75157.1 - 1.3e-22 79.1 0.6 4.1e-22 77.5 0.6 1.9 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 RUS75157.1 - 1.3e-21 76.8 8.2 4e-21 75.2 8.2 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 RUS75157.1 - 6.8e-17 61.6 5.0 0.00013 22.4 0.4 6.0 4 2 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 RUS75157.1 - 7e-15 55.2 0.1 0.0014 18.9 0.0 4.8 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 RUS75157.1 - 6.7e-09 35.3 1.1 0.18 12.2 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.20 RUS75157.1 - 6e-07 28.4 0.1 5e-05 22.0 0.0 2.8 2 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 RUS75157.1 - 3.3e-06 27.2 1.2 0.14 12.2 0.2 3.7 3 2 1 4 4 4 3 V-ATPase subunit H Arm_2 PF04826.13 RUS75157.1 - 6.9e-05 22.4 0.0 1.1 8.7 0.0 3.8 1 1 0 3 3 3 2 Armadillo-like Mrpl_C PF18502.1 RUS75157.1 - 0.0092 16.2 0.1 0.025 14.9 0.1 1.7 1 0 0 1 1 1 1 54S ribosomal protein L8 C-terminal domain ParcG PF10274.9 RUS75157.1 - 0.039 14.1 0.3 17 5.5 0.1 3.1 1 1 1 3 3 3 0 Parkin co-regulated protein RICTOR_V PF14668.6 RUS75157.1 - 0.075 13.3 3.7 2.5 8.4 0.0 4.1 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 RUS75157.1 - 0.12 12.3 0.1 3.3 7.6 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) FOP_dimer PF09398.10 RUS75158.1 - 9.5e-21 73.9 0.9 2e-20 72.8 0.9 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain EF-hand_6 PF13405.6 RUS75158.1 - 7.4e-09 34.8 4.2 1.5e-05 24.5 0.7 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS75158.1 - 1.1e-07 32.2 7.0 1.6e-07 31.6 5.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair LisH_2 PF16045.5 RUS75158.1 - 2.4e-07 29.6 0.1 5.8e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 LisH EF-hand_1 PF00036.32 RUS75158.1 - 6.4e-07 28.5 8.4 6.6e-05 22.2 1.4 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 RUS75158.1 - 4.5e-05 22.7 8.6 0.00064 19.1 0.6 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RUS75158.1 - 0.003 17.4 5.1 0.42 10.5 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair Cofac_haem_bdg PF04187.13 RUS75158.1 - 0.062 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN RabGAP-TBC PF00566.18 RUS75160.1 - 0.056 13.1 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain AAA_lid_2 PF17863.1 RUS75160.1 - 0.086 12.7 0.8 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA lid domain RabGAP-TBC PF00566.18 RUS75161.1 - 1.6e-09 37.8 0.8 1.6e-09 37.8 0.8 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box-like PF12937.7 RUS75162.1 - 5.7e-14 51.7 0.8 1.5e-13 50.4 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS75162.1 - 1.1e-05 25.2 0.0 3.3e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 RUS75162.1 - 0.0033 16.9 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box DUF1118 PF06549.12 RUS75163.1 - 0.02 15.2 0.1 0.037 14.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) Vanabin-2 PF11437.8 RUS75163.1 - 0.43 10.7 14.1 2.5 8.3 3.6 2.2 2 0 0 2 2 2 0 Vanadium-binding protein 2 Jiv90 PF14901.6 RUS75163.1 - 2.3 8.4 19.5 2.7e+02 1.8 5.6 5.4 1 1 0 2 2 2 0 Cleavage inducing molecular chaperone BESS PF02944.20 RUS75165.1 - 3.6e-07 29.9 0.0 6.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 BESS motif LIN37 PF15306.6 RUS75165.1 - 5 7.3 7.9 16 5.7 7.9 1.8 1 1 0 1 1 1 0 LIN37 7tm_1 PF00001.21 RUS75166.1 - 7.7e-24 84.4 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Renin_r PF07850.14 RUS75166.1 - 0.0083 16.7 1.0 0.022 15.3 1.0 1.7 1 0 0 1 1 1 1 Renin receptor-like protein PalH PF08733.10 RUS75166.1 - 0.075 12.0 3.0 0.16 11.0 3.0 1.4 1 0 0 1 1 1 0 PalH/RIM21 XRN1_D2_D3 PF18334.1 RUS75167.1 - 0.023 14.9 0.4 5.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain GIY-YIG PF01541.24 RUS75167.1 - 0.057 13.7 5.0 1.3 9.3 0.3 2.6 2 1 0 3 3 3 0 GIY-YIG catalytic domain OLF PF02191.16 RUS75169.1 - 2.8e-52 177.7 0.0 3.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Pkinase_Tyr PF07714.17 RUS75171.1 - 5.6e-37 127.4 0.3 3.2e-31 108.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS75171.1 - 2.9e-28 99.0 0.0 4.2e-23 82.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 RUS75171.1 - 0.0049 16.2 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Paramyxo_NS_C PF02725.14 RUS75171.1 - 0.17 12.0 0.5 0.58 10.3 0.0 2.1 3 0 0 3 3 3 0 Non-structural protein C RVT_1 PF00078.27 RUS75172.1 - 6.1e-08 32.5 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RUS75173.1 - 6.1e-34 117.5 0.1 7.2e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YlmH_RBD PF17774.1 RUS75173.1 - 0.14 12.5 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Amino_oxidase PF01593.24 RUS75174.1 - 9.1e-52 176.8 0.1 2e-51 175.7 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS75174.1 - 4.4e-12 46.1 0.2 1e-11 44.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS75174.1 - 5.2e-07 29.2 0.2 9.3e-07 28.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS75174.1 - 2e-06 27.2 0.4 2.9e-06 26.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RUS75174.1 - 5.3e-06 26.2 0.5 1.7e-05 24.6 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 RUS75174.1 - 0.00016 21.2 0.6 0.00027 20.4 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS75174.1 - 0.00087 18.1 1.0 0.0011 17.8 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 RUS75174.1 - 0.0011 18.3 0.2 0.0023 17.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RUS75174.1 - 0.016 14.3 0.1 0.066 12.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RUS75174.1 - 0.017 14.4 0.5 1.8 7.7 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS75174.1 - 0.019 14.1 0.2 0.034 13.2 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 RUS75174.1 - 0.067 12.0 0.3 0.11 11.4 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 RUS75174.1 - 0.08 13.5 0.2 0.28 11.8 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS75174.1 - 0.091 12.7 0.4 16 5.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 RUS75174.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) UPF0489 PF12640.7 RUS75175.1 - 5.3e-18 65.9 3.6 3.7e-17 63.1 3.6 2.1 1 1 0 1 1 1 1 UPF0489 domain DUF2729 PF10870.8 RUS75175.1 - 0.041 13.8 4.2 2.1 8.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) AceK PF06315.11 RUS75176.1 - 0.22 9.9 0.0 0.23 9.9 0.0 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Folate_rec PF03024.14 RUS75177.1 - 6e-13 49.0 1.4 1.1e-12 48.2 1.4 1.3 1 0 0 1 1 1 1 Folate receptor family RVT_1 PF00078.27 RUS75177.1 - 1.2e-11 44.6 0.0 3.5e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_permease_2 PF13520.6 RUS75178.1 - 1e-36 126.7 19.9 1.2e-36 126.4 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS75178.1 - 1.9e-20 72.9 17.3 2.4e-20 72.6 17.3 1.1 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.11 RUS75178.1 - 0.31 10.8 5.5 0.13 12.0 1.0 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF751 PF05421.11 RUS75178.1 - 0.85 10.4 11.5 1.7 9.4 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF751) AA_permease_C PF13906.6 RUS75179.1 - 3.3e-24 84.7 7.5 4.7e-24 84.2 7.5 1.2 1 0 0 1 1 1 1 C-terminus of AA_permease DUF1097 PF06496.11 RUS75179.1 - 0.014 15.5 0.6 0.015 15.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Anoctamin PF04547.12 RUS75180.1 - 2.2e-165 550.9 9.7 2.8e-165 550.5 9.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RUS75180.1 - 5.1e-70 235.7 0.1 8.4e-70 235.0 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 RUS75180.1 - 0.87 8.3 17.2 0.49 9.1 5.0 3.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) UPF0182 PF03699.13 RUS75180.1 - 3.8 5.5 6.2 1.1 7.3 2.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) 7TM_GPCR_Srx PF10328.9 RUS75181.1 - 1.7e-07 31.2 7.1 4e-07 29.9 7.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS75181.1 - 3.3e-05 23.3 6.8 6.7e-05 22.3 6.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS75181.1 - 0.0044 17.0 1.4 0.0044 17.0 1.4 2.4 1 1 2 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srw PF10324.9 RUS75181.1 - 0.012 14.9 9.3 0.25 10.6 9.3 2.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw YfzA PF14118.6 RUS75181.1 - 0.025 15.0 0.0 0.025 15.0 0.0 2.4 3 1 0 3 3 3 0 YfzA-like protein DUF202 PF02656.15 RUS75181.1 - 0.27 11.7 1.7 0.97 9.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF3169 PF11368.8 RUS75181.1 - 0.46 9.9 4.8 0.32 10.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) ABC2_membrane_5 PF13346.6 RUS75181.1 - 3.5 7.1 13.8 13 5.2 11.0 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein Wzy_C PF04932.15 RUS75181.1 - 9.5 5.8 7.5 43 3.7 7.5 2.1 1 1 0 1 1 1 0 O-Antigen ligase Arf PF00025.21 RUS75183.1 - 1.4e-31 109.3 0.0 5.1e-30 104.2 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Nup54_57_C PF18570.1 RUS75184.1 - 0.0027 17.2 2.4 1.2e+02 2.4 0.0 6.2 6 0 0 6 6 6 0 NUP57/Nup54 C-terminal domain Annexin PF00191.20 RUS75184.1 - 0.0076 16.3 0.0 8.8 6.5 0.0 3.9 3 1 1 4 4 4 1 Annexin Peptidase_C62 PF12380.8 RUS75184.1 - 0.014 14.5 0.2 1.8 7.6 0.1 2.4 1 1 1 2 2 2 0 Gill-associated viral 3C-like peptidase Ph1570 PF09638.10 RUS75184.1 - 0.022 14.6 0.0 13 5.6 0.0 2.7 1 1 2 3 3 3 0 Ph1570 protein MetJ PF01340.20 RUS75184.1 - 0.46 10.5 3.7 6.2 6.9 0.2 3.4 1 1 2 4 4 4 0 Met Apo-repressor, MetJ DUF445 PF04286.12 RUS75185.1 - 3e-07 30.6 0.0 6.4e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF445) Herpes_UL92 PF03048.14 RUS75185.1 - 0.048 13.4 11.1 0.11 12.3 1.0 4.2 1 1 4 5 5 5 0 UL92 family DUF3819 PF12842.7 RUS75185.1 - 0.26 11.2 2.4 16 5.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3819) MSSP PF03940.13 RUS75186.1 - 0.76 9.4 63.5 1.8e+04 -32.8 63.5 4.5 1 1 0 1 1 1 0 Male specific sperm protein DUF3793 PF12672.7 RUS75187.1 - 7e-10 39.2 9.5 0.084 12.9 0.0 5.0 2 2 3 5 5 5 3 Protein of unknown function (DUF3793) OrfB_Zn_ribbon PF07282.11 RUS75187.1 - 5.9e-08 32.5 0.2 0.67 9.9 0.1 4.2 4 0 0 4 4 4 1 Putative transposase DNA-binding domain zf-A20 PF01754.16 RUS75187.1 - 3e-07 30.3 18.6 1.6 8.8 0.2 5.2 5 0 0 5 5 5 5 A20-like zinc finger Phage_lambda_P PF06992.11 RUS75187.1 - 8.7e-07 28.8 2.1 0.13 12.0 0.2 4.0 1 1 2 4 4 4 3 Replication protein P GATA PF00320.27 RUS75187.1 - 6.5e-05 22.5 5.2 24 4.7 0.1 5.2 5 0 0 5 5 5 0 GATA zinc finger MRP-L28 PF09812.9 RUS75187.1 - 7.7e-05 22.9 3.3 8 6.6 0.1 4.5 1 1 4 5 5 5 0 Mitochondrial ribosomal protein L28 DZR PF12773.7 RUS75187.1 - 0.00026 20.9 4.8 1.3 9.1 4.8 3.4 1 1 0 1 1 1 1 Double zinc ribbon UPF0193 PF05250.11 RUS75187.1 - 0.00052 19.9 0.4 22 4.7 0.0 4.8 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0193) DUF5056 PF16479.5 RUS75187.1 - 0.00061 20.0 2.6 91 3.4 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5056) RecR PF02132.15 RUS75187.1 - 0.0016 17.9 3.7 58 3.4 0.0 5.0 5 0 0 5 5 5 0 RecR protein DUF4709 PF15821.5 RUS75187.1 - 0.026 14.8 0.7 89 3.4 0.0 3.9 1 1 3 5 5 5 0 Domain of unknown function (DUF4709) Ribosomal_L31 PF01197.18 RUS75187.1 - 0.034 14.4 0.9 81 3.5 0.0 4.3 5 0 0 5 5 5 0 Ribosomal protein L31 zinc_ribbon_15 PF17032.5 RUS75187.1 - 0.046 14.5 7.0 9.6 7.0 2.4 3.2 1 1 1 3 3 3 0 zinc-ribbon family PI3_PI4_kinase PF00454.27 RUS75187.1 - 0.12 12.2 0.0 1.4e+02 2.1 0.0 3.6 1 1 2 4 4 4 0 Phosphatidylinositol 3- and 4-kinase ATP-synt_G PF04718.15 RUS75187.1 - 0.16 12.8 2.1 1.6 9.6 0.6 3.0 1 1 2 3 3 3 0 Mitochondrial ATP synthase g subunit CxC5 PF18718.1 RUS75187.1 - 0.17 12.0 6.3 18 5.4 0.4 4.3 1 1 1 4 4 4 0 CxC5 like cysteine cluster associated with KDZ transposases MBD_C PF14048.6 RUS75187.1 - 0.17 12.6 4.2 21 5.9 0.1 3.7 1 1 3 4 4 4 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF2179 PF10035.9 RUS75187.1 - 0.18 11.6 0.0 51 3.7 0.0 4.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF1284 PF06935.11 RUS75187.1 - 0.21 12.1 7.0 9.6 6.7 0.9 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1284) Rubredoxin PF00301.20 RUS75187.1 - 0.26 11.4 10.2 27 4.9 0.1 5.0 5 0 0 5 5 5 0 Rubredoxin UME PF08064.13 RUS75187.1 - 0.38 10.7 10.8 9.1 6.3 0.1 4.3 1 1 1 3 3 3 0 UME (NUC010) domain zf-RING_5 PF14634.6 RUS75187.1 - 0.46 10.5 9.1 1.2e+02 2.8 0.9 4.7 4 1 1 5 5 5 0 zinc-RING finger domain zinc_ribbon_5 PF13719.6 RUS75187.1 - 0.57 10.0 8.9 96 2.9 0.2 5.0 5 0 0 5 5 5 0 zinc-ribbon domain DUF35_N PF12172.8 RUS75187.1 - 0.68 9.9 12.3 81 3.2 0.1 5.0 5 0 0 5 5 5 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CEBP_ZZ PF16366.5 RUS75187.1 - 0.8 10.0 13.5 77 3.6 0.1 5.0 5 0 0 5 5 5 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4 PF00097.25 RUS75187.1 - 6.7 6.7 12.6 35 4.4 3.5 4.5 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Lectin_C PF00059.21 RUS75188.1 - 1e-06 29.4 0.0 1.2e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Trypsin_2 PF13365.6 RUS75189.1 - 0.00015 22.7 0.0 0.00029 21.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Kinesin PF00225.23 RUS75190.1 - 7.3e-100 334.1 0.2 1.3e-99 333.3 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS75190.1 - 8.8e-26 90.6 0.1 2.2e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 RUS75190.1 - 7.4e-12 45.4 0.0 2.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 RUS75190.1 - 0.021 15.4 0.0 0.16 12.6 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Thioredoxin_14 PF18402.1 RUS75190.1 - 0.042 13.8 0.2 4.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like domain ATPase_2 PF01637.18 RUS75190.1 - 0.067 13.1 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HHH_2 PF12826.7 RUS75190.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF5069 PF16798.5 RUS75190.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Peptidase_M16 PF00675.20 RUS75191.1 - 7.4e-55 185.0 0.1 1.1e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RUS75191.1 - 2.3e-40 138.5 0.0 8.9e-39 133.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Anti-TRAP PF15777.5 RUS75192.1 - 0.0012 18.7 37.9 12 6.0 0.3 10.8 1 1 7 8 8 8 8 Tryptophan RNA-binding attenuator protein inhibitory protein SPRR2 PF14820.6 RUS75192.1 - 0.24 11.5 28.1 6.8 6.9 4.9 4.1 1 1 2 3 3 3 0 Small proline-rich 2 3D PF06725.11 RUS75192.1 - 0.27 11.5 0.5 63 3.9 0.0 3.8 1 1 2 3 3 3 0 3D domain Sema PF01403.19 RUS75193.1 - 6.8e-20 71.3 0.0 9.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG_2 PF18020.1 RUS75194.1 - 2.8e-18 66.3 0.0 1.6e-15 57.5 0.0 2.4 2 0 0 2 2 2 2 TIG domain found in plexin PSI PF01437.25 RUS75194.1 - 9.3e-11 42.1 46.7 9.1e-05 22.9 13.6 3.7 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 RUS75194.1 - 7.2e-07 29.1 0.4 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 TIG domain PSI_integrin PF17205.3 RUS75194.1 - 0.44 10.3 40.4 0.037 13.8 9.1 3.7 3 0 0 3 3 3 0 Integrin plexin domain Pkinase_Tyr PF07714.17 RUS75195.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TIG PF01833.24 RUS75195.1 - 1.2e-29 102.2 10.2 1e-12 47.9 0.4 4.5 4 0 0 4 4 4 4 IPT/TIG domain Pkinase PF00069.25 RUS75195.1 - 9.6e-13 48.1 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Syndecan PF01034.20 RUS75195.1 - 0.14 12.1 0.3 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain FAM176 PF14851.6 RUS75195.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF1397 PF07165.11 RUS75198.1 - 0.084 12.3 1.4 0.1 12.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) FEZ PF07763.13 RUS75198.1 - 0.098 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 FEZ-like protein zf-CCCH_2 PF14608.6 RUS75198.1 - 8.7 7.0 6.9 16 6.1 0.7 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Complex1_LYR PF05347.15 RUS75199.1 - 3.9e-09 36.4 0.0 6.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS75199.1 - 0.062 14.1 0.0 0.084 13.6 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Ribosomal_L34e PF01199.18 RUS75200.1 - 3.8e-42 142.5 5.4 4.8e-42 142.2 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e 3HCDH_N PF02737.18 RUS75201.1 - 5.4e-61 205.6 1.9 2.4e-60 203.5 2.6 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RUS75201.1 - 6.2e-36 122.9 0.1 2.7e-35 120.9 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RUS75201.1 - 1e-06 29.0 1.5 3.1e-06 27.4 1.5 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 RUS75201.1 - 4.8e-05 23.8 0.3 0.00011 22.7 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 RUS75201.1 - 5.4e-05 22.8 0.9 0.00013 21.7 0.9 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 RUS75201.1 - 7.7e-05 23.2 3.9 0.00032 21.2 3.9 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 RUS75201.1 - 0.00011 21.6 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 RUS75201.1 - 0.00015 22.0 0.7 0.0003 21.1 0.7 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 RUS75201.1 - 0.00041 20.7 0.4 0.00076 19.9 0.4 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 RUS75201.1 - 0.00047 19.6 0.2 0.00087 18.7 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 RUS75201.1 - 0.00061 19.8 1.8 0.0022 18.0 1.8 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 RUS75201.1 - 0.00065 19.1 2.9 0.0012 18.2 2.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 RUS75201.1 - 0.002 18.4 1.0 0.0053 17.0 1.0 1.8 1 1 0 1 1 1 1 TrkA-N domain DAO PF01266.24 RUS75201.1 - 0.002 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS75201.1 - 0.0023 17.1 0.1 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 RUS75201.1 - 0.0038 17.4 0.4 0.0079 16.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NmrA PF05368.13 RUS75201.1 - 0.0055 16.3 3.1 0.0086 15.7 3.1 1.3 1 0 0 1 1 1 1 NmrA-like family XdhC_C PF13478.6 RUS75201.1 - 0.0056 17.2 0.2 0.0086 16.6 0.2 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain DFP PF04127.15 RUS75201.1 - 0.0089 15.9 6.0 0.1 12.4 6.0 2.1 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 RUS75201.1 - 0.013 15.2 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 RUS75201.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF276 PF03434.13 RUS75201.1 - 0.024 13.8 0.3 0.049 12.8 0.2 1.4 1 1 0 1 1 1 0 DUF276 ELFV_dehydrog PF00208.21 RUS75201.1 - 0.024 14.4 0.7 0.034 13.9 0.7 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 RUS75201.1 - 0.037 13.5 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 RUS75201.1 - 0.065 13.9 0.3 0.16 12.7 0.3 1.7 1 1 0 1 1 1 0 Methyltransferase domain I_LWEQ PF01608.17 RUS75201.1 - 0.08 13.2 2.0 0.11 12.7 1.3 1.6 2 0 0 2 2 1 0 I/LWEQ domain Shikimate_DH PF01488.20 RUS75201.1 - 0.084 12.9 0.8 0.25 11.4 0.7 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Xylo_C PF12529.8 RUS75202.1 - 3.5e-49 166.9 0.0 5.4e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 RUS75202.1 - 4.2e-40 137.8 0.0 6.9e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme EHD_N PF16880.5 RUS75202.1 - 0.032 14.1 1.4 0.11 12.4 1.4 2.0 1 0 0 1 1 1 0 N-terminal EH-domain containing protein WSC PF01822.19 RUS75203.1 - 1e-18 67.2 9.3 2e-18 66.4 9.3 1.5 1 0 0 1 1 1 1 WSC domain Branch PF02485.21 RUS75203.1 - 0.025 14.1 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Core-2/I-Branching enzyme SNF2_N PF00176.23 RUS75204.1 - 9.1e-64 215.4 0.0 1.5e-63 214.7 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS75204.1 - 2.4e-16 60.0 0.0 6e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.8 RUS75204.1 - 4.2e-09 36.2 1.2 8.1e-09 35.2 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) HEAT PF02985.22 RUS75204.1 - 9.3e-06 25.5 1.1 0.28 11.5 0.1 3.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 RUS75204.1 - 0.1 13.0 0.1 1.5 9.2 0.1 2.6 1 1 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 RUS75204.1 - 0.16 12.0 0.4 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RUS75204.1 - 0.16 12.5 0.0 0.47 11.1 0.0 1.8 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region EGF PF00008.27 RUS75205.1 - 1.1 9.7 3.5 3.1 8.2 0.1 2.3 2 0 0 2 2 2 0 EGF-like domain Cytochrom_B561 PF03188.16 RUS75207.1 - 2.4e-42 144.3 12.5 1.7e-41 141.5 7.8 2.4 3 0 0 3 3 3 2 Eukaryotic cytochrome b561 DUF4079 PF13301.6 RUS75207.1 - 4 7.6 17.9 10 6.2 8.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) PMT_4TMC PF16192.5 RUS75207.1 - 5.6 6.5 11.7 0.31 10.6 3.2 2.1 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Somatomedin_B PF01033.17 RUS75208.1 - 1.1e-06 28.9 9.9 3.5e-06 27.3 9.9 1.9 1 0 0 1 1 1 1 Somatomedin B domain Slu7 PF11708.8 RUS75208.1 - 0.016 15.0 0.7 0.029 14.1 0.7 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DNA_pol_phi PF04931.13 RUS75208.1 - 0.096 10.8 13.1 0.15 10.2 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS75208.1 - 0.11 11.0 2.9 0.17 10.4 2.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 RUS75208.1 - 0.39 10.4 1.8 0.83 9.3 1.8 1.5 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 RUS75208.1 - 0.43 10.8 13.1 0.69 10.1 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RUS75208.1 - 0.87 8.9 20.9 2 7.7 20.9 1.5 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RUS75208.1 - 1.3 8.6 6.7 2.2 7.8 6.7 1.3 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 RUS75208.1 - 3 6.9 23.6 4.4 6.3 23.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 RUS75208.1 - 4.1 7.4 9.2 0.49 10.4 4.6 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Utp14 PF04615.13 RUS75208.1 - 7.7 5.0 7.7 11 4.5 7.7 1.1 1 0 0 1 1 1 0 Utp14 protein UPF0054 PF02130.17 RUS75209.1 - 2.3e-27 95.3 0.6 2.8e-27 95.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 ERK-JNK_inhib PF15002.6 RUS75209.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor QVR PF17064.5 RUS75210.1 - 0.019 15.2 9.1 0.03 14.6 9.1 1.3 1 0 0 1 1 1 0 Sleepless protein HLH PF00010.26 RUS75211.1 - 6.6e-17 61.2 0.1 9.8e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_C69 PF03577.15 RUS75212.1 - 3.4e-07 29.5 0.0 7.4e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 RUS75212.1 - 7.3e-05 22.6 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Sun2_CC2 PF18580.1 RUS75212.1 - 0.19 12.0 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 PH PF00169.29 RUS75213.1 - 2.9e-15 56.6 0.9 4e-15 56.2 0.9 1.2 1 0 0 1 1 1 1 PH domain YkuD PF03734.14 RUS75213.1 - 0.0057 17.1 0.0 0.0097 16.3 0.0 1.3 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain WW PF00397.26 RUS75213.1 - 0.07 13.2 0.3 0.07 13.2 0.3 2.0 2 0 0 2 2 2 0 WW domain PH_9 PF15410.6 RUS75213.1 - 0.1 13.0 1.4 2 8.8 1.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 RUS75213.1 - 0.13 12.7 7.8 0.1 13.1 3.9 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain Ank_2 PF12796.7 RUS75214.1 - 3.1e-45 152.7 8.4 8.5e-17 61.5 0.3 3.6 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75214.1 - 2.5e-35 120.4 7.6 2.7e-13 50.1 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS75214.1 - 5.3e-27 93.5 10.3 2.6e-11 43.5 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75214.1 - 1.6e-26 89.4 0.4 9.5e-06 25.6 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RUS75214.1 - 7.2e-26 89.5 6.8 6e-05 23.3 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat UQ_con PF00179.26 RUS75215.1 - 1.9e-52 176.7 0.0 2.1e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS75215.1 - 0.0002 21.6 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 RUS75215.1 - 0.003 17.2 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RUS75215.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain adh_short_C2 PF13561.6 RUS75216.1 - 2.7e-64 216.9 0.2 3.1e-64 216.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS75216.1 - 5.1e-52 176.2 0.7 6.3e-52 175.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS75216.1 - 3.4e-13 49.9 0.2 4.5e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 KR domain CPL PF08144.11 RUS75217.1 - 9.3e-40 136.3 1.0 1.7e-38 132.2 0.0 3.4 4 0 0 4 4 4 1 CPL (NUC119) domain AMP-binding PF00501.28 RUS75221.1 - 7.6e-98 327.9 0.1 9.1e-98 327.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS75221.1 - 3.7e-21 75.9 0.1 7.4e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RUS75221.1 - 2.9e-20 71.9 0.9 8.3e-20 70.5 0.9 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus zf-H2C2_2 PF13465.6 RUS75222.1 - 0.12 12.9 3.6 1.4 9.5 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain DUF3134 PF11332.8 RUS75222.1 - 1.4 9.3 6.0 2.2 8.7 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) ATP-synt_S1 PF05827.12 RUS75222.1 - 6.2 6.6 5.8 4 7.3 0.7 2.4 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) zf-H2C2_5 PF13909.6 RUS75223.1 - 9.5e-05 22.1 0.3 9.5e-05 22.1 0.3 5.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 RUS75223.1 - 0.012 15.2 0.2 0.012 15.2 0.2 6.6 5 2 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 RUS75223.1 - 0.018 15.4 0.5 0.018 15.4 0.5 5.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type F5_F8_type_C PF00754.25 RUS75224.1 - 0.008 16.3 1.1 0.03 14.5 0.3 2.1 2 0 0 2 2 2 1 F5/8 type C domain Ank_2 PF12796.7 RUS75226.1 - 2.8e-78 258.6 15.4 7.7e-14 52.1 0.2 13.3 11 1 3 14 14 14 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75226.1 - 3.3e-66 218.8 17.0 6.7e-08 32.9 0.0 18.0 15 4 3 18 18 18 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS75226.1 - 2.6e-52 174.2 25.1 3.3e-06 27.3 0.2 16.2 11 3 5 16 16 16 11 Ankyrin repeats (many copies) Ank PF00023.30 RUS75226.1 - 1.4e-44 148.7 21.1 0.00095 19.5 0.0 20.3 22 0 0 22 22 22 10 Ankyrin repeat Ank_3 PF13606.6 RUS75226.1 - 6.8e-43 139.7 23.9 0.00078 19.7 0.0 21.8 25 0 0 25 25 25 9 Ankyrin repeat PARP PF00644.20 RUS75226.1 - 1.9e-35 122.2 0.0 6.9e-35 120.4 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 RUS75226.1 - 4.4e-20 71.5 0.8 1.3e-19 70.0 0.8 1.9 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 RUS75226.1 - 1e-18 67.8 0.3 2.8e-18 66.3 0.3 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain DUF4746 PF15928.5 RUS75226.1 - 0.65 9.4 5.6 0.12 11.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 RUS75226.1 - 8.7 5.6 11.3 8.6 5.6 9.4 1.9 2 0 0 2 2 2 0 NOA36 protein Ribosomal_L13 PF00572.18 RUS75227.1 - 6.1e-31 107.3 0.0 8.2e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Alg14 PF08660.11 RUS75228.1 - 5.3e-64 215.4 0.1 6.6e-64 215.0 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like LRR_8 PF13855.6 RUS75229.1 - 0.00042 20.0 1.1 0.0007 19.3 1.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat EGF_MSP1_1 PF12946.7 RUS75229.1 - 0.003 17.6 4.4 0.0072 16.4 4.4 1.7 1 0 0 1 1 1 1 MSP1 EGF domain 1 EGF_3 PF12947.7 RUS75229.1 - 0.26 11.5 8.1 0.67 10.2 8.1 1.8 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 RUS75229.1 - 0.36 11.2 6.9 1.4 9.4 6.9 2.1 1 1 0 1 1 1 0 EGF-like domain IF-2B PF01008.17 RUS75230.1 - 1.7e-81 273.6 0.8 1.9e-81 273.4 0.8 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_transf_21 PF13506.6 RUS75231.1 - 1.7e-50 170.9 0.0 2.2e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RUS75231.1 - 8.4e-20 71.6 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RUS75231.1 - 1.2e-12 48.1 2.2 1.8e-12 47.6 2.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 RUS75231.1 - 0.0059 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 7tm_1 PF00001.21 RUS75232.1 - 1e-43 149.6 18.0 1.7e-43 148.8 18.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75232.1 - 1.3e-10 41.1 14.2 1.9e-10 40.6 14.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS75232.1 - 0.0013 18.5 15.9 0.0038 17.0 15.9 1.8 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 RUS75232.1 - 0.003 17.0 12.5 0.0066 15.8 12.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS75232.1 - 0.35 10.5 11.6 0.86 9.2 11.6 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TUG-UBL1 PF11470.8 RUS75236.1 - 7.4e-21 74.2 0.0 2.8e-20 72.3 0.0 2.1 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 RUS75236.1 - 7.4e-16 58.1 0.4 4.6e-09 36.4 0.1 3.6 3 0 0 3 3 3 3 UBX domain Rad60-SLD PF11976.8 RUS75236.1 - 0.00025 20.8 0.2 0.24 11.2 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like RBD PF02196.15 RUS75236.1 - 0.043 13.9 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF2559 PF10832.8 RUS75237.1 - 4.2e-06 26.7 55.2 5.3 7.2 1.1 14.5 1 1 18 19 19 19 19 Protein of unknown function (DUF2559) SSF PF00474.17 RUS75238.1 - 7.4e-42 143.6 26.0 1e-41 143.1 26.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Pox_A14 PF05767.12 RUS75238.1 - 0.82 9.9 4.9 18 5.6 0.1 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 RUS75239.1 - 1.5e-13 50.7 84.2 2.6e-12 46.6 84.2 2.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Hydrophob_seed PF14547.6 RUS75239.1 - 0.0065 16.6 0.7 0.029 14.6 0.7 2.1 1 0 0 1 1 1 1 Hydrophobic seed protein BRCT_2 PF16589.5 RUS75240.1 - 0.00029 21.2 18.9 14 6.2 0.1 6.5 1 1 2 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RUS75240.1 - 0.016 15.6 8.5 59 4.1 0.7 6.6 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Glyoxalase PF00903.25 RUS75240.1 - 0.065 13.4 2.0 34 4.6 2.0 4.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7tm_1 PF00001.21 RUS75241.1 - 5.8e-42 143.8 14.1 7e-42 143.6 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75241.1 - 8e-10 38.5 9.6 1e-09 38.2 9.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS75241.1 - 0.0044 16.7 10.8 0.0044 16.7 10.8 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 RUS75241.1 - 0.016 14.3 0.1 0.016 14.3 0.1 2.1 2 1 1 3 3 3 0 Taste receptor protein (TAS2R) Git3 PF11710.8 RUS75241.1 - 1.1 9.1 13.7 3.3 7.4 7.5 2.4 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 EMC3_TMCO1 PF01956.16 RUS75242.1 - 2.6e-06 27.3 0.1 4.5e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CitMHS PF03600.16 RUS75242.1 - 0.0012 18.1 1.5 0.0017 17.7 1.5 1.1 1 0 0 1 1 1 1 Citrate transporter HemY_N PF07219.13 RUS75242.1 - 0.0014 18.8 1.8 0.0014 18.8 1.8 2.2 1 1 1 2 2 1 1 HemY protein N-terminus DUF2244 PF10003.9 RUS75242.1 - 0.0027 17.4 7.5 0.0044 16.7 7.5 1.3 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) Plasmodium_Vir PF05795.11 RUS75242.1 - 0.017 14.6 9.0 0.025 14.0 9.1 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein MCM_bind PF09739.9 RUS75242.1 - 0.085 11.3 10.2 0.13 10.7 10.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PNISR PF15996.5 RUS75242.1 - 0.12 12.7 26.9 0.026 14.8 23.1 1.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF5313 PF17240.2 RUS75242.1 - 0.31 11.5 7.1 0.59 10.6 7.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) YfhO PF09586.10 RUS75242.1 - 0.32 9.2 1.3 0.41 8.8 1.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Wzy_C PF04932.15 RUS75242.1 - 0.34 10.5 4.6 0.57 9.8 4.6 1.3 1 0 0 1 1 1 0 O-Antigen ligase Hid1 PF12722.7 RUS75242.1 - 0.34 9.0 7.2 0.41 8.7 7.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.20 RUS75242.1 - 0.77 8.0 5.1 1.3 7.2 4.7 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SLC12 PF03522.15 RUS75242.1 - 0.96 8.4 10.2 1.3 8.0 10.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 RUS75242.1 - 1 7.8 4.7 1.1 7.7 4.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 Myc_target_1 PF15179.6 RUS75242.1 - 1.2 9.0 4.2 2 8.3 4.2 1.3 1 0 0 1 1 1 0 Myc target protein 1 Raftlin PF15250.6 RUS75242.1 - 5.2 5.7 15.4 8 5.1 15.4 1.3 1 0 0 1 1 1 0 Raftlin Wzy_C_2 PF11846.8 RUS75242.1 - 6.9 6.6 7.6 14 5.6 7.6 1.5 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Gal-bind_lectin PF00337.22 RUS75243.1 - 3.6e-45 152.8 2.0 4.1e-29 100.8 0.1 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin PPR_2 PF13041.6 RUS75244.1 - 7.8e-13 48.4 3.5 0.00089 19.4 0.6 5.7 6 0 0 6 6 6 3 PPR repeat family PPR_long PF17177.4 RUS75244.1 - 2.8e-10 39.9 0.3 1.5e-08 34.2 0.2 2.3 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 RUS75244.1 - 5.3e-07 29.6 0.8 0.0029 17.7 0.0 3.5 1 1 3 4 4 4 4 Pentatricopeptide repeat domain RPM2 PF08579.11 RUS75244.1 - 1e-05 25.9 2.2 0.0006 20.2 0.1 3.9 3 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.20 RUS75244.1 - 0.27 11.6 4.4 52 4.4 1.1 4.6 5 0 0 5 5 5 0 PPR repeat MAM PF00629.23 RUS75245.1 - 2.6e-07 30.7 0.2 8.3e-07 29.1 0.2 2.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu PhyH PF05721.13 RUS75247.1 - 2.3e-09 37.8 0.0 3.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4689 PF15755.5 RUS75247.1 - 0.097 12.3 0.1 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4689) Nucleos_tra2_C PF07662.13 RUS75248.1 - 2.9e-48 164.5 6.1 2.9e-48 164.5 6.1 1.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS75248.1 - 4.6e-18 65.6 2.3 4.6e-18 65.6 2.3 3.2 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Ank_5 PF13857.6 RUS75248.1 - 0.025 14.9 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Nexin_C PF08628.12 RUS75249.1 - 1.5e-24 86.7 0.0 5.3e-24 85.0 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 RUS75249.1 - 3.2e-19 69.3 0.1 3.2e-19 69.3 0.1 3.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain PXA PF02194.15 RUS75249.1 - 2e-14 54.0 2.6 1.4e-13 51.2 0.0 3.1 3 0 0 3 3 3 1 PXA domain PX PF00787.24 RUS75249.1 - 2.7e-11 43.5 0.0 9.2e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 PX domain MYEOV2 PF15004.6 RUS75249.1 - 0.12 12.8 0.5 15 6.1 0.2 3.0 2 0 0 2 2 2 0 Myeloma-overexpressed-like Spectrin PF00435.21 RUS75249.1 - 0.47 11.0 10.2 0.25 11.9 4.9 2.6 2 0 0 2 2 2 0 Spectrin repeat Noelin-1 PF12308.8 RUS75249.1 - 0.82 9.7 3.8 3.1 7.8 3.8 2.0 1 0 0 1 1 1 0 Neurogenesis glycoprotein Exonuc_VII_L PF02601.15 RUS75249.1 - 0.88 9.1 4.6 0.37 10.3 2.0 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM76 PF16046.5 RUS75249.1 - 2.6 7.3 7.1 0.23 10.8 1.7 1.8 2 0 0 2 2 2 0 FAM76 protein DUF1043 PF06295.12 RUS75249.1 - 4.2 7.4 7.8 0.52 10.3 2.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) PXA PF02194.15 RUS75250.1 - 6.7e-17 62.0 0.9 1.2e-16 61.3 0.9 1.4 1 0 0 1 1 1 1 PXA domain ThrE PF06738.12 RUS75250.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative threonine/serine exporter DinB_2 PF12867.7 RUS75250.1 - 0.036 14.6 0.0 0.18 12.3 0.0 2.0 1 1 1 2 2 2 0 DinB superfamily DUF4131 PF13567.6 RUS75250.1 - 0.14 11.8 0.9 0.2 11.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Nucleos_tra2_C PF07662.13 RUS75251.1 - 9.7e-46 156.2 7.6 2.4e-45 154.9 7.6 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS75251.1 - 1.1e-17 64.4 2.8 1.1e-17 64.4 2.8 3.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus 7tm_1 PF00001.21 RUS75254.1 - 2.2e-50 171.4 21.1 2.9e-50 171.0 21.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75254.1 - 1.6e-08 34.3 21.0 2.2e-08 33.8 21.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS75254.1 - 1.8e-06 27.8 17.8 1.8e-06 27.8 17.8 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Nop14 PF04147.12 RUS75254.1 - 1.2 7.3 27.7 1.7 6.8 27.7 1.1 1 0 0 1 1 1 0 Nop14-like family MWFE PF15879.5 RUS75254.1 - 2.8 8.2 4.1 26 5.1 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DNA_pol_phi PF04931.13 RUS75254.1 - 8.8 4.3 48.5 12 3.9 48.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi 7tm_1 PF00001.21 RUS75255.1 - 1.8e-50 171.7 22.3 2.5e-50 171.2 22.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75255.1 - 1.1e-09 38.1 21.6 1.1e-09 38.1 21.6 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS75255.1 - 8.4e-06 25.6 24.6 1.7e-05 24.6 24.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DMA PF03474.14 RUS75256.1 - 2.1e-15 56.0 0.1 3.6e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.16 RUS75256.1 - 0.004 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ribosomal_60s PF00428.19 RUS75256.1 - 0.37 11.4 4.2 1.2 9.8 4.2 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DM PF00751.18 RUS75257.1 - 3.3e-22 78.1 13.7 7.5e-22 77.0 13.7 1.6 1 0 0 1 1 1 1 DM DNA binding domain DMA PF03474.14 RUS75257.1 - 5.9e-18 64.2 0.2 1.1e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 DMRTA motif HlyD_2 PF12700.7 RUS75257.1 - 0.58 8.8 1.4 0.83 8.3 1.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Auts2 PF15336.6 RUS75258.1 - 5.9 7.0 5.6 14 5.7 0.7 2.5 2 1 0 2 2 2 0 Autism susceptibility gene 2 protein S6OS1 PF15676.5 RUS75260.1 - 1.4e-09 37.1 15.0 1.4e-09 37.1 15.0 2.1 1 1 1 2 2 2 1 Six6 opposite strand transcript 1 family DUF4164 PF13747.6 RUS75260.1 - 0.0034 17.6 7.5 0.11 12.8 1.0 3.2 2 2 1 3 3 3 2 Domain of unknown function (DUF4164) DUF769 PF05590.11 RUS75260.1 - 0.11 12.0 1.1 0.16 11.4 0.3 1.6 1 1 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Glyco_hydro_67C PF07477.12 RUS75260.1 - 0.13 11.8 2.4 0.12 11.9 0.3 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus DUF2730 PF10805.8 RUS75260.1 - 0.44 10.7 12.0 1.3 9.2 1.9 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) Rootletin PF15035.6 RUS75260.1 - 0.61 10.1 32.4 0.026 14.6 5.0 3.4 2 2 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion NTP_transf_4 PF13562.6 RUS75260.1 - 0.7 10.1 3.8 7.9 6.7 0.0 2.8 2 1 1 3 3 3 0 Sugar nucleotidyl transferase EzrA PF06160.12 RUS75260.1 - 1.3 7.1 31.8 0.024 12.9 5.0 3.2 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA ThiD2 PF17792.1 RUS75260.1 - 1.5 9.3 12.5 0.41 11.1 1.3 2.9 2 1 0 2 2 2 0 ThiD2 family LPP PF04728.13 RUS75260.1 - 3.4 8.1 9.9 20 5.7 1.1 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SOGA PF11365.8 RUS75260.1 - 3.6 8.8 17.1 0.69 11.1 2.9 4.3 1 1 1 4 4 4 0 Protein SOGA HAUS-augmin3 PF14932.6 RUS75260.1 - 5.5 6.5 23.3 6.3 6.3 6.2 2.7 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Metallophos_C PF14008.6 RUS75262.1 - 1.4e-22 80.3 0.1 3.6e-22 79.0 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 RUS75262.1 - 9.2e-22 78.5 0.3 1.8e-21 77.6 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS75262.1 - 0.0021 18.3 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 RUS75262.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 RUS75263.1 - 1.2e-13 51.5 0.1 1.7e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 RUS75263.1 - 0.038 14.5 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Gp5_C PF06715.12 RUS75263.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) COX7a PF02238.15 RUS75264.1 - 0.00048 20.5 0.0 0.00066 20.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Ank_2 PF12796.7 RUS75265.1 - 1.7e-53 179.1 5.0 1.4e-15 57.7 0.0 5.3 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75265.1 - 3.8e-46 154.9 0.9 2.3e-12 47.1 0.0 8.1 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS75265.1 - 8.3e-39 131.1 9.8 1.3e-10 41.3 0.4 8.5 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75265.1 - 2.8e-37 122.5 1.5 5e-06 26.5 0.0 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 RUS75265.1 - 1.9e-31 107.1 12.8 5.6e-06 26.6 0.1 10.1 10 0 0 10 10 10 7 Ankyrin repeat EF-hand_7 PF13499.6 RUS75265.1 - 0.00016 22.1 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS75265.1 - 0.00019 20.7 0.1 0.37 10.4 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS75265.1 - 0.0019 18.0 0.1 1.5 9.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS75265.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_4 PF12763.7 RUS75265.1 - 0.064 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 RUS75266.1 - 1.5e-63 214.7 0.1 2.1e-63 214.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75266.1 - 4.3e-30 104.8 0.0 7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS75266.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS75266.1 - 0.00058 19.3 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L34 PF00468.17 RUS75266.1 - 0.0096 15.9 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L34 RIO1 PF01163.22 RUS75266.1 - 0.013 15.1 0.2 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 RUS75266.1 - 0.028 14.0 0.3 0.055 13.1 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PWI PF01480.17 RUS75267.1 - 3.2e-14 53.0 0.5 7.4e-14 51.8 0.5 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 RUS75267.1 - 3.1e-08 33.3 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.27 RUS75268.1 - 1.5e-34 119.3 6.7 3e-32 111.8 4.5 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RUS75268.1 - 2e-27 95.3 0.0 6.7e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RUS75268.1 - 2.4e-08 34.0 0.0 5.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS75268.1 - 4.5e-07 29.5 1.5 2.7e-06 27.0 1.3 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 RUS75268.1 - 5.7e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 RUS75268.1 - 0.00082 19.4 0.3 0.0026 17.7 0.1 2.0 2 0 0 2 2 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU_D2 PF03144.25 RUS75268.1 - 0.00095 19.5 2.0 1.4 9.4 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 RUS75268.1 - 0.001 19.0 3.7 0.085 12.8 0.8 2.8 1 1 1 2 2 2 2 RsgA GTPase MeaB PF03308.16 RUS75268.1 - 0.001 18.1 0.8 0.0029 16.7 0.8 1.7 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 RUS75268.1 - 0.0011 18.7 0.7 0.0037 17.0 0.7 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 RUS75268.1 - 0.009 15.5 0.1 0.022 14.2 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RUS75268.1 - 0.038 14.2 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FluMu_N PF17891.1 RUS75268.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain HTH_15 PF12324.8 RUS75268.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Dynamin_N PF00350.23 RUS75268.1 - 0.2 11.7 1.0 9.1 6.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family RIBIOP_C PF04950.12 RUS75269.1 - 2.2e-106 355.6 0.2 3.6e-106 354.9 0.2 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RUS75269.1 - 1.4e-25 89.2 0.0 3.4e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain eIF-3c_N PF05470.12 RUS75269.1 - 3.9 5.7 8.0 8.5 4.5 8.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pentapeptide_4 PF13599.6 RUS75270.1 - 0.034 14.3 0.0 0.094 12.9 0.0 1.7 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) EGF_2 PF07974.13 RUS75270.1 - 0.12 12.8 1.3 0.61 10.5 1.3 2.2 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.27 RUS75270.1 - 0.27 11.6 7.0 1.9 8.9 7.0 2.4 1 1 0 1 1 1 0 EGF-like domain Auto_anti-p27 PF06677.12 RUS75272.1 - 1.3e-13 50.8 2.8 2.3e-13 50.0 2.8 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4611 PF15387.6 RUS75273.1 - 0.0017 18.6 23.5 0.75 10.0 23.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 RUS75273.1 - 0.017 14.9 15.1 0.019 14.7 15.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 RUS75273.1 - 0.035 14.4 15.3 0.038 14.3 15.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 RUS75273.1 - 0.044 13.8 10.3 0.063 13.3 10.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RUS75273.1 - 0.064 12.6 16.2 0.073 12.4 16.2 1.2 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 RUS75273.1 - 0.073 11.0 10.4 0.088 10.8 10.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2457 PF10446.9 RUS75273.1 - 0.098 11.8 20.9 0.11 11.7 20.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS75273.1 - 0.25 9.4 20.4 0.3 9.1 20.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 RUS75273.1 - 0.35 8.9 8.6 0.32 9.0 8.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 RUS75273.1 - 0.57 8.4 11.5 0.61 8.3 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 RUS75273.1 - 0.76 8.1 7.8 0.7 8.3 7.8 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 RUS75273.1 - 1.8 6.7 14.5 1.6 6.8 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RUS75273.1 - 1.8 8.2 9.0 2.8 7.6 9.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF2076 PF09849.9 RUS75273.1 - 5.8 6.9 10.5 6.2 6.8 10.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HECT PF00632.25 RUS75276.1 - 2.9e-58 197.8 0.1 4.4e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 RUS75276.1 - 1.5e-31 108.7 0.3 2.8e-31 107.8 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 RUS75276.1 - 1.1e-30 105.5 2.8 4.6e-28 97.1 1.4 2.8 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 RUS75276.1 - 2.6e-16 59.4 0.0 1.6e-09 37.7 0.1 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 RUS75276.1 - 4e-10 39.9 0.2 9.9e-10 38.6 0.2 1.6 1 0 0 1 1 1 1 C2 domain Methyltransf_25 PF13649.6 RUS75277.1 - 0.015 16.0 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 RUS75277.1 - 0.042 12.9 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.6 RUS75277.1 - 0.054 13.3 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RUS75277.1 - 0.077 13.6 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2730 PF10805.8 RUS75278.1 - 0.055 13.6 0.1 0.055 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FapA PF03961.13 RUS75278.1 - 5.3 5.5 10.0 1 7.9 0.5 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-CCCH PF00642.24 RUS75279.1 - 8.8e-23 79.7 15.4 2.3e-11 43.3 2.9 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS75279.1 - 1e-12 47.7 14.6 5.4e-07 29.5 2.3 3.0 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RUS75279.1 - 2.9e-07 30.1 12.5 6.2e-05 22.7 1.3 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 RUS75279.1 - 0.022 15.4 15.8 0.89 10.3 3.9 3.6 2 1 1 3 3 3 0 Torus domain zf-CCCH_2 PF14608.6 RUS75279.1 - 0.72 10.4 25.8 0.1 13.1 0.9 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 RUS75279.1 - 2.3 8.8 7.0 4.9 7.7 0.5 2.7 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region DUF2663 PF10864.8 RUS75280.1 - 0.043 14.2 1.8 0.057 13.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Peptidase_U4 PF03419.13 RUS75280.1 - 0.1 11.9 2.7 0.11 11.8 2.7 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA HemY_N PF07219.13 RUS75280.1 - 0.11 12.7 1.0 8.2 6.7 0.7 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Chordopox_A13L PF05961.11 RUS75282.1 - 1.6e-07 31.5 6.0 1 9.7 0.2 4.0 1 1 3 4 4 4 4 Chordopoxvirus A13L protein DUF3716 PF12511.8 RUS75282.1 - 7e-06 26.0 24.9 1 9.4 1.2 5.0 1 1 4 5 5 5 5 Protein of unknown function (DUF3716) CxC6 PF18721.1 RUS75282.1 - 6.8e-05 23.1 44.3 0.35 11.2 3.5 5.0 1 1 4 5 5 5 4 CxC6 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 RUS75282.1 - 0.0059 16.9 6.6 88 3.5 0.0 5.0 5 0 0 5 5 5 0 Caulimovirus viroplasmin Kelch_2 PF07646.15 RUS75282.1 - 0.01 15.8 2.4 77 3.5 0.0 4.1 4 1 0 4 4 4 0 Kelch motif Pox_T4_C PF04490.12 RUS75282.1 - 2.3 8.4 29.3 6.5 6.9 2.0 4.0 1 1 3 4 4 4 0 Poxvirus T4 protein, C terminus Glyco_transf_8 PF01501.20 RUS75284.1 - 1.6e-16 60.6 0.4 2.4e-16 60.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RUS75284.1 - 0.00023 20.6 1.5 0.00037 20.0 1.5 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 RUS75284.1 - 0.058 12.7 0.1 0.09 12.1 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative COX6C PF02937.15 RUS75284.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc CS PF04969.16 RUS75285.1 - 0.00059 20.8 0.4 0.0012 19.8 0.3 1.7 1 1 0 1 1 1 1 CS domain Myb_DNA-bind_6 PF13921.6 RUS75285.1 - 0.015 15.5 0.2 0.032 14.5 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain AAA PF00004.29 RUS75286.1 - 6.4e-36 123.7 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RUS75286.1 - 1.5e-19 69.7 0.7 2.2e-18 66.0 0.1 3.2 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 RUS75286.1 - 2.9e-14 52.8 0.6 2.9e-14 52.8 0.6 2.5 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RUS75286.1 - 2.2e-10 40.1 0.0 7.3e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RUS75286.1 - 6.9e-05 23.3 0.1 0.00034 21.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RUS75286.1 - 0.00014 21.9 0.1 0.0023 17.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS75286.1 - 0.00018 21.8 0.5 0.0018 18.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS75286.1 - 0.00032 20.5 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RUS75286.1 - 0.00049 19.4 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 RUS75286.1 - 0.00057 19.9 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RUS75286.1 - 0.0016 18.6 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 RUS75286.1 - 0.0016 18.3 0.0 1.1 9.1 0.0 2.5 1 1 1 2 2 2 2 NACHT domain RuvB_N PF05496.12 RUS75286.1 - 0.0018 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RUS75286.1 - 0.0019 17.8 0.3 0.38 10.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS75286.1 - 0.003 17.7 0.0 0.0095 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 RUS75286.1 - 0.01 14.9 0.0 0.075 12.1 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 RUS75286.1 - 0.011 16.3 0.0 0.054 14.0 0.0 2.2 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.13 RUS75286.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RUS75286.1 - 0.031 14.0 0.3 0.14 11.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RUS75286.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 RUS75286.1 - 0.039 13.4 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 RUS75286.1 - 0.042 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RUS75286.1 - 0.048 13.0 0.1 8 5.7 0.0 2.6 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 RUS75286.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PP1 PF07430.11 RUS75286.1 - 0.057 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain USP8_dimer PF08969.11 RUS75286.1 - 0.099 12.8 1.9 0.18 12.0 0.7 2.1 2 1 0 2 2 1 0 USP8 dimerisation domain Zeta_toxin PF06414.12 RUS75286.1 - 0.12 11.7 0.0 0.35 10.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 RUS75286.1 - 0.12 12.8 0.0 0.51 10.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 RUS75287.1 - 3.2e-36 124.7 0.0 6e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS75287.1 - 1.6e-05 24.6 0.0 5.4e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RUS75287.1 - 5.2e-05 23.7 0.1 0.0003 21.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS75287.1 - 9.8e-05 22.7 0.1 0.0013 19.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS75287.1 - 0.00017 21.6 0.0 0.0021 18.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 RUS75287.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RUS75287.1 - 0.00026 20.3 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 RUS75287.1 - 0.00066 19.6 0.0 0.64 9.9 0.0 2.5 1 1 1 2 2 2 2 NACHT domain AAA_14 PF13173.6 RUS75287.1 - 0.0007 19.6 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RUS75287.1 - 0.00073 19.7 0.0 0.002 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 RUS75287.1 - 0.0012 18.5 0.4 0.24 10.9 0.1 2.5 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 RUS75287.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RUS75287.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS75287.1 - 0.0089 16.6 0.0 0.047 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 RUS75287.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 RUS75287.1 - 0.012 15.0 0.0 0.063 12.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 RUS75287.1 - 0.021 14.5 0.0 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 RUS75287.1 - 0.025 14.0 0.1 5 6.4 0.0 2.2 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.17 RUS75287.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 RUS75287.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 RUS75287.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 RUS75287.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RUS75287.1 - 0.093 12.0 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 RUS75287.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 RUS75287.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Drf_FH1 PF06346.12 RUS75288.1 - 0.0082 15.9 64.5 0.28 10.9 34.0 3.0 2 1 0 2 2 2 2 Formin Homology Region 1 PRCC PF10253.9 RUS75288.1 - 8.9 7.0 7.4 18 6.1 7.4 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MADF_DNA_bdg PF10545.9 RUS75289.1 - 1.8e-18 66.6 2.6 2.2e-18 66.3 2.6 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 RUS75289.1 - 0.001 19.4 2.7 0.0015 18.9 2.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 RUS75289.1 - 0.024 15.3 0.6 0.034 14.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Methyltransf_11 PF08241.12 RUS75290.1 - 1.1e-13 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS75290.1 - 2.6e-13 50.5 0.0 3.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS75290.1 - 3.2e-10 40.1 0.0 3.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS75290.1 - 1.1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS75290.1 - 1.9e-07 31.7 0.0 2.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS75290.1 - 4.8e-07 29.7 0.0 5.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 RUS75290.1 - 0.004 15.8 0.0 0.0046 15.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 RUS75290.1 - 0.01 15.4 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 RUS75290.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 RUS75290.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase SH3_1 PF00018.28 RUS75291.1 - 1.8e-09 37.1 0.0 2.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS75291.1 - 3e-09 36.6 0.1 5.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS75291.1 - 0.00041 20.0 0.1 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Glyco_hydro_5_C PF18564.1 RUS75291.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain SepRS_C PF18006.1 RUS75293.1 - 0.0031 17.6 6.8 1.2e+02 2.9 0.0 8.0 6 2 4 10 10 10 0 O-phosphoseryl-tRNA synthetase C-terminal domain Gp58 PF07902.11 RUS75293.1 - 0.022 13.1 0.0 0.064 11.5 0.0 1.6 1 1 0 1 1 1 0 gp58-like protein GNAT_acetyltran PF12746.7 RUS75293.1 - 4.2 6.9 18.0 3.9 7.0 1.4 3.7 1 1 2 3 3 3 0 GNAT acetyltransferase VIT1 PF01988.19 RUS75293.1 - 4.4 7.1 7.0 8.2 6.2 1.7 2.1 1 1 1 2 2 2 0 VIT family Acyl_transf_1 PF00698.21 RUS75294.1 - 1.5e-67 228.4 0.0 4.4e-67 226.9 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.26 RUS75294.1 - 4.9e-50 170.5 0.0 8.6e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 RUS75294.1 - 5.7e-41 140.4 0.0 1.1e-40 139.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 RUS75294.1 - 2.8e-34 117.7 0.0 5.7e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 RUS75294.1 - 4.8e-32 110.7 0.0 1.1e-31 109.6 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 RUS75294.1 - 1e-17 64.4 0.0 2.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 RUS75294.1 - 8.1e-14 52.8 0.1 3.6e-13 50.7 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RUS75294.1 - 4e-09 36.6 0.0 2.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 RUS75294.1 - 6.3e-07 29.0 0.0 1.4e-05 24.7 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 RUS75294.1 - 7.5e-07 29.4 0.7 1.7e-06 28.3 0.7 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 RUS75294.1 - 0.04 14.6 0.0 0.15 12.7 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RUS75294.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Acyl_transf_1 PF00698.21 RUS75295.1 - 5.8e-58 196.9 0.0 2.8e-57 194.7 0.0 2.1 2 1 0 2 2 2 1 Acyl transferase domain KR PF08659.10 RUS75295.1 - 8.2e-37 126.9 0.0 1.8e-36 125.7 0.0 1.6 2 0 0 2 2 2 1 KR domain KAsynt_C_assoc PF16197.5 RUS75295.1 - 2.6e-32 111.6 0.0 5.8e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 RUS75295.1 - 4.7e-30 105.0 0.1 7.7e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS75295.1 - 1.9e-24 86.0 0.0 4.5e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 RUS75295.1 - 9.5e-14 52.6 0.0 2.9e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 RUS75295.1 - 3.3e-12 46.2 0.5 1.3e-06 27.8 0.1 2.4 1 1 1 2 2 2 2 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 RUS75295.1 - 9e-09 35.4 0.0 3.2e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 RUS75295.1 - 0.00057 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 RUS75295.1 - 0.00078 18.9 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase LapA_dom PF06305.11 RUS75296.1 - 2.9 7.8 7.1 23 4.9 7.1 2.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AMOP PF03782.17 RUS75299.1 - 0.14 12.2 2.4 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 AMOP domain Joubert PF15392.6 RUS75299.1 - 7.1 6.2 10.4 0.39 10.4 2.7 2.1 1 1 0 2 2 2 0 Joubert syndrome-associated PKD_channel PF08016.12 RUS75301.1 - 0.00094 18.0 0.0 0.00098 17.9 0.0 1.0 1 0 0 1 1 1 1 Polycystin cation channel EF-hand_6 PF13405.6 RUS75303.1 - 0.00019 21.1 0.2 0.00019 21.1 0.2 2.9 2 1 1 3 3 3 1 EF-hand domain RRN3 PF05327.11 RUS75303.1 - 2.5 6.6 18.3 3.4 6.1 18.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 RUS75303.1 - 9.1 4.2 32.1 14 3.6 32.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi HEAT_2 PF13646.6 RUS75304.1 - 8.2e-18 64.6 7.6 7.8e-06 26.2 0.6 4.5 1 1 2 4 4 4 4 HEAT repeats HEAT PF02985.22 RUS75304.1 - 1.5e-12 46.6 5.7 0.036 14.3 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 RUS75304.1 - 0.029 14.9 6.5 2.9 8.5 0.3 4.8 4 2 1 5 5 5 0 HEAT-like repeat Arm PF00514.23 RUS75304.1 - 0.25 11.5 0.6 9.8 6.4 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 RUS75304.1 - 2.3 9.1 6.4 30 5.7 0.1 4.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_19 PF14559.6 RUS75304.1 - 2.4 8.7 4.0 7.1 7.2 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CobT PF06213.12 RUS75305.1 - 5.7 6.2 25.6 7.1 5.9 25.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 RUS75305.1 - 6.2 4.9 29.5 6.6 4.8 29.5 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 RUS75305.1 - 6.6 6.8 19.3 9.2 6.3 19.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pox_A_type_inc PF04508.12 RUS75306.1 - 0.13 12.2 3.0 0.16 11.9 0.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Josephin PF02099.17 RUS75307.1 - 1.9e-26 93.1 0.2 2.5e-24 86.2 0.2 2.3 1 1 0 1 1 1 1 Josephin RUN PF02759.19 RUS75308.1 - 2.3e-22 79.4 0.8 4.6e-22 78.4 0.2 1.9 2 0 0 2 2 2 1 RUN domain PX PF00787.24 RUS75308.1 - 3.7e-14 52.7 0.2 3.7e-14 52.7 0.2 2.4 3 0 0 3 3 3 1 PX domain SHE3 PF17078.5 RUS75308.1 - 2 8.1 10.8 0.15 11.7 4.8 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Ribosomal_L16 PF00252.18 RUS75309.1 - 2.3e-42 144.1 0.1 2.8e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CECR6_TMEM121 PF14997.6 RUS75311.1 - 1.6e-36 126.0 5.5 1.6e-36 126.0 5.5 1.8 2 0 0 2 2 2 1 CECR6/TMEM121 family UPF0014 PF03649.13 RUS75311.1 - 0.2 11.0 10.2 0.12 11.8 8.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0014) 7TMR-DISM_7TM PF07695.11 RUS75311.1 - 0.76 9.6 16.2 3.8 7.4 8.1 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling SAPS PF04499.15 RUS75313.1 - 0.005 15.7 1.2 0.0043 15.9 1.2 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein RRN3 PF05327.11 RUS75313.1 - 0.087 11.4 27.1 0.11 11.0 27.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PT PF04886.12 RUS75313.1 - 0.092 12.3 7.2 0.16 11.6 7.2 1.4 1 0 0 1 1 1 0 PT repeat Nop14 PF04147.12 RUS75313.1 - 0.14 10.4 32.9 0.19 9.9 32.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 RUS75313.1 - 0.23 11.9 1.9 0.36 11.2 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 RUS75313.1 - 0.23 9.5 49.3 0.29 9.2 49.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RUS75313.1 - 4.6 5.6 27.2 6 5.2 27.2 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RUS75313.1 - 5.4 6.3 27.6 9.3 5.5 27.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FERM_N PF09379.10 RUS75315.1 - 1.9e-08 34.1 0.0 4.6e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 FERM N-terminal domain RVT_1 PF00078.27 RUS75316.1 - 1.4e-10 41.1 0.7 8.2e-10 38.6 0.3 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) AKAP7_NLS PF10469.9 RUS75316.1 - 0.0077 16.1 0.7 0.035 14.0 0.5 2.0 2 1 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain XPC-binding PF09280.11 RUS75316.1 - 0.093 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 XPC-binding domain Z1 PF10593.9 RUS75316.1 - 0.97 8.9 6.5 3.7 7.0 2.7 2.3 2 0 0 2 2 2 0 Z1 domain DUF3915 PF13054.6 RUS75319.1 - 7 6.7 7.3 11 6.0 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) ig PF00047.25 RUS75321.1 - 3.2e-07 30.4 0.1 1.8e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 RUS75321.1 - 2.3e-06 28.1 0.1 1.1e-05 26.0 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS75321.1 - 5.5e-05 23.3 0.3 0.00073 19.7 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain IL6Ra-bind PF09240.10 RUS75321.1 - 7.6e-05 23.1 0.9 0.00016 22.0 0.8 1.6 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Ig_2 PF13895.6 RUS75321.1 - 0.0036 17.6 0.2 0.057 13.8 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RUS75321.1 - 0.006 16.6 1.0 0.091 12.8 0.0 2.8 2 2 0 2 2 2 1 Immunoglobulin I-set domain TPMT PF05724.11 RUS75322.1 - 2.5e-40 138.5 0.0 4.9e-40 137.5 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 RUS75322.1 - 4.7e-05 24.0 0.0 0.00043 20.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS75322.1 - 0.00013 22.6 0.0 0.00075 20.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 RUS75322.1 - 0.00027 20.6 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 RUS75322.1 - 0.0027 17.0 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FAM91_C PF14648.6 RUS75324.1 - 2.2e-162 540.8 0.0 3.1e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 RUS75324.1 - 1.5e-144 481.0 0.0 1.9e-144 480.7 0.0 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Glyco_hydro_31 PF01055.26 RUS75325.1 - 7.9e-125 417.5 0.0 1.1e-124 417.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RUS75325.1 - 3.3e-19 69.2 0.0 6e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RUS75325.1 - 2.3e-06 27.8 0.0 6.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like SKG6 PF08693.10 RUS75325.1 - 0.2 11.1 3.5 0.4 10.1 3.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Trefoil PF00088.18 RUS75325.1 - 1.2 9.1 4.0 0.63 10.0 1.7 1.7 2 0 0 2 2 2 0 Trefoil (P-type) domain Herpes_BLLF1 PF05109.13 RUS75326.1 - 6.2e-07 27.8 5.0 7.3e-07 27.6 5.0 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Nuc_recep-AF1 PF11825.8 RUS75326.1 - 0.00014 21.9 26.4 0.12 12.5 5.5 3.1 1 1 2 3 3 3 3 Nuclear/hormone receptor activator site AF-1 DUF4744 PF15918.5 RUS75326.1 - 0.00025 21.8 23.3 0.007 17.2 12.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4744) MSSP PF03940.13 RUS75326.1 - 0.57 9.8 35.4 1.8e+04 -10.5 35.4 3.4 1 1 0 1 1 1 0 Male specific sperm protein DUF3089 PF11288.8 RUS75326.1 - 2.4 7.7 12.3 21 4.6 0.4 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF3089) DAZAP2 PF11029.8 RUS75326.1 - 4.2 8.3 7.9 1.2e+02 3.6 7.9 2.1 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) RNase_T PF00929.24 RUS75327.1 - 2.5e-34 119.2 0.0 4.5e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease PT PF04886.12 RUS75328.1 - 3.5e-10 39.2 56.3 5.3e-07 29.1 22.1 2.6 1 1 1 2 2 2 2 PT repeat FTP PF07504.13 RUS75328.1 - 0.017 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 RUS75329.1 - 2.2e-22 79.7 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain SH3_4 PF06347.13 RUS75329.1 - 0.2 11.5 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain NFACT-R_1 PF05670.13 RUS75330.1 - 3.1e-42 143.6 0.3 5.3e-42 142.9 0.3 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain SRP14 PF02290.15 RUS75330.1 - 0.42 11.0 5.7 1.1 9.6 5.7 1.7 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Eapp_C PF10238.9 RUS75331.1 - 1e-49 168.5 4.0 1e-49 168.5 4.0 2.7 2 1 1 3 3 3 1 E2F-associated phosphoprotein zf-AN1 PF01428.16 RUS75331.1 - 0.44 10.8 4.3 16 5.7 0.1 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.12 RUS75331.1 - 1.4 9.2 7.2 0.29 11.4 1.7 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain CCSAP PF15748.5 RUS75331.1 - 2 8.5 20.5 59 3.7 20.5 2.2 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated Yippee-Mis18 PF03226.14 RUS75331.1 - 3.2 8.0 7.4 12 6.2 7.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CCDC106 PF15794.5 RUS75331.1 - 3.5 7.3 21.6 0.27 10.9 9.0 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 106 IBR PF01485.21 RUS75331.1 - 4.2 7.7 11.3 1.7 8.9 2.7 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain ABC_trans_CmpB PF06541.11 RUS75332.1 - 2.1e-06 28.0 11.2 3.1e-06 27.5 11.2 1.3 1 0 0 1 1 1 1 Putative ABC-transporter type IV Glyco_hydro_18 PF00704.28 RUS75333.1 - 3e-59 201.3 0.0 4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 RUS75333.1 - 5.4e-14 52.1 13.9 1.5e-07 31.5 3.6 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Mucin PF01456.17 RUS75333.1 - 0.19 11.7 29.1 0.41 10.6 29.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Septin PF00735.18 RUS75335.1 - 6.9e-100 333.9 1.2 1.3e-99 333.1 1.2 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RUS75335.1 - 3.2e-05 24.0 2.3 3.9e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Peptidase_S49 PF01343.18 RUS75335.1 - 0.0024 17.8 2.1 0.0024 17.8 2.1 1.8 2 0 0 2 2 2 1 Peptidase family S49 AAA_16 PF13191.6 RUS75335.1 - 0.0032 17.9 0.1 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS75335.1 - 0.0072 16.6 0.9 0.015 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 RUS75335.1 - 0.0076 16.5 0.2 0.036 14.3 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 RUS75335.1 - 0.017 14.6 0.3 0.055 13.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 RUS75335.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 RUS75335.1 - 0.06 13.4 6.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 RUS75335.1 - 0.077 12.9 5.7 0.54 10.1 0.0 3.2 3 1 1 4 4 4 0 RsgA GTPase GTP_EFTU PF00009.27 RUS75335.1 - 0.29 10.7 9.3 11 5.5 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RUS75335.1 - 0.41 11.2 3.8 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 RUS75335.1 - 3.2 7.8 7.5 61 3.6 0.0 3.5 2 2 1 3 3 3 0 Dynamin family Sulfatase PF00884.23 RUS75336.1 - 1e-47 163.1 0.2 7.4e-46 156.9 0.1 2.2 2 0 0 2 2 2 2 Sulfatase DUF229 PF02995.17 RUS75336.1 - 9.7e-05 21.2 0.1 0.00028 19.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RUS75336.1 - 0.0021 17.7 0.0 0.069 12.7 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CDI PF02234.19 RUS75337.1 - 8.2e-06 25.9 0.2 1.4e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor INTS2 PF14750.6 RUS75338.1 - 8.3e-40 136.3 2.8 9e-40 136.1 2.8 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 7tm_1 PF00001.21 RUS75339.1 - 1.3e-31 109.9 8.9 2.7e-31 108.9 8.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75339.1 - 5.8e-07 29.1 12.0 5.8e-07 29.1 12.0 2.9 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 RUS75339.1 - 1.2 8.9 26.3 0.44 10.3 20.4 2.7 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Gp-FAR-1 PF05823.12 RUS75342.1 - 2e-06 28.2 7.9 0.037 14.4 0.5 3.7 1 1 2 3 3 3 3 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Mucin-like PF16058.5 RUS75342.1 - 7.8e-05 22.7 0.0 0.11 12.6 0.0 2.0 1 1 1 2 2 2 2 Mucin-like ApoLp-III PF07464.11 RUS75342.1 - 0.00013 22.1 2.2 0.0025 17.9 2.2 2.0 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) PTP2 PF17022.5 RUS75342.1 - 0.00014 21.6 41.3 0.28 10.8 3.6 5.0 1 1 4 5 5 5 4 Polar tube protein 2 from Microsporidia Flavin_Reduct PF01613.18 RUS75342.1 - 0.0061 16.6 8.3 25 4.9 8.3 3.0 1 1 0 1 1 1 0 Flavin reductase like domain DUF4473 PF14747.6 RUS75342.1 - 0.0062 17.1 0.2 4.7 7.8 0.1 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4473) PLC-beta_C PF08703.10 RUS75342.1 - 0.01 15.8 9.8 0.21 11.6 3.6 2.1 1 1 1 2 2 2 0 PLC-beta C terminal Bromo_TP PF07524.13 RUS75342.1 - 0.027 14.5 0.0 3.2 7.8 0.0 2.8 1 1 2 3 3 3 0 Bromodomain associated AstA PF04958.12 RUS75342.1 - 0.041 12.4 0.0 2.5 6.6 0.0 2.4 1 1 2 3 3 3 0 Arginine N-succinyltransferase beta subunit RNase_J_C PF17770.1 RUS75342.1 - 0.16 13.1 10.0 3.7 8.7 0.8 2.7 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain YtxH PF12732.7 RUS75342.1 - 0.17 12.4 5.1 36 5.0 5.1 2.5 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 RUS75342.1 - 0.18 11.6 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PCP PF02429.15 RUS75342.1 - 0.21 11.9 1.5 13 6.1 0.1 2.8 1 1 2 3 3 3 0 Peridinin-chlorophyll A binding protein Dynamin_M PF01031.20 RUS75342.1 - 0.35 10.0 12.9 0.25 10.5 3.2 2.1 1 1 1 2 2 2 0 Dynamin central region ArlS_N PF18719.1 RUS75342.1 - 0.41 10.9 4.3 8.5 6.6 0.4 2.4 1 1 1 2 2 2 0 ArlS sensor domain MBR1 PF17058.5 RUS75342.1 - 0.46 10.7 26.5 3.4e+03 -1.9 26.5 3.2 1 1 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Syntaxin_2 PF14523.6 RUS75342.1 - 0.54 10.7 21.1 0.74 10.2 6.9 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF3974 PF13120.6 RUS75342.1 - 0.56 10.3 9.6 3.2 7.9 2.4 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF3974) Exonuc_VII_L PF02601.15 RUS75342.1 - 0.92 9.0 9.6 1.1 8.7 9.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uteroglobin PF01099.17 RUS75342.1 - 1.1 9.7 22.2 20 5.6 0.9 5.1 1 1 4 5 5 5 0 Uteroglobin family DUF1708 PF08101.11 RUS75342.1 - 5.4 6.0 18.7 1.5 7.9 3.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1708) DUF4462 PF14692.6 RUS75342.1 - 6.3 6.4 39.2 20 4.7 0.1 9.5 4 1 7 11 11 11 0 Domain of unknown function (DUF4462) zf-CCCH PF00642.24 RUS75343.1 - 0.062 13.2 0.4 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TES PF08034.11 RUS75344.1 - 1.6e-08 34.7 2.1 1.6 9.0 0.0 5.7 1 1 3 4 4 4 4 Trematode eggshell synthesis protein Gal-bind_lectin PF00337.22 RUS75348.1 - 3e-05 23.6 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Y_phosphatase PF00102.27 RUS75353.1 - 1.4e-164 545.2 0.7 2.4e-82 276.1 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RUS75353.1 - 1.9e-110 361.5 24.4 1.7e-14 54.0 0.0 9.8 9 0 0 9 9 9 8 Fibronectin type III domain I-set PF07679.16 RUS75353.1 - 6.9e-35 119.0 0.1 7.6e-16 58.0 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS75353.1 - 9.6e-34 115.8 0.4 4.5e-15 56.0 0.1 4.4 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS75353.1 - 7.5e-24 84.1 12.3 0.02 15.4 0.0 9.8 8 3 0 8 8 8 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 RUS75353.1 - 9.7e-19 67.5 1.5 5.3e-09 36.3 0.0 3.9 4 0 0 4 4 3 2 Immunoglobulin domain ig PF00047.25 RUS75353.1 - 1.7e-18 66.5 0.1 3.8e-08 33.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Interfer-bind PF09294.10 RUS75353.1 - 1e-11 45.0 0.0 2.6 8.4 0.0 7.6 7 0 0 7 7 7 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 RUS75353.1 - 6.8e-09 35.6 0.1 0.0029 17.4 0.0 2.8 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain C2-set_2 PF08205.12 RUS75353.1 - 4.8e-07 29.8 0.0 0.00047 20.2 0.0 2.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 RUS75353.1 - 5.8e-07 29.6 0.6 0.1 12.8 0.0 6.4 7 1 0 7 7 7 1 Fibronectin type III domain Y_phosphatase3 PF13350.6 RUS75353.1 - 8.1e-06 26.0 0.0 0.04 13.9 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family V-set PF07686.17 RUS75353.1 - 4.3e-05 23.6 0.2 0.0019 18.3 0.0 3.7 3 1 0 3 3 2 1 Immunoglobulin V-set domain PTPlike_phytase PF14566.6 RUS75353.1 - 7.8e-05 22.8 0.0 0.027 14.6 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2369 PF10179.9 RUS75353.1 - 0.0011 19.3 0.0 38 4.8 0.0 4.8 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) Ig_C17orf99 PF17736.1 RUS75353.1 - 0.0022 18.0 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 C17orf99 Ig domain DUF4945 PF16303.5 RUS75353.1 - 0.0038 17.1 0.9 0.27 11.2 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4945) CBM_4_9 PF02018.17 RUS75353.1 - 0.0042 17.4 2.8 1.1 9.5 0.0 5.2 7 1 0 7 7 5 1 Carbohydrate binding domain Herpes_gp2 PF05955.11 RUS75353.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Reeler PF02014.16 RUS75353.1 - 4 8.2 7.2 92 3.8 0.1 4.9 3 1 2 5 5 5 0 Reeler domain GIY-YIG PF01541.24 RUS75354.1 - 1e-06 28.9 0.1 2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain SWC7 PF17330.2 RUS75355.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 EGF_3 PF12947.7 RUS75357.1 - 0.00065 19.8 2.1 0.00065 19.8 2.1 4.0 5 0 0 5 5 5 1 EGF domain Kazal_2 PF07648.15 RUS75357.1 - 0.00077 19.5 7.2 0.00077 19.5 7.2 3.1 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EGF_CA PF07645.15 RUS75357.1 - 0.00097 19.3 4.6 0.00097 19.3 4.6 4.6 5 1 1 6 6 6 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS75357.1 - 0.0046 17.2 3.6 0.0046 17.2 3.6 5.3 6 3 0 6 6 6 1 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RUS75357.1 - 0.017 15.7 1.5 0.017 15.7 1.5 6.6 7 1 0 7 7 7 0 Human growth factor-like EGF C8 PF08742.11 RUS75359.1 - 3e-10 40.4 4.1 3e-10 40.4 4.1 3.8 2 1 0 2 2 2 1 C8 domain EGF_CA PF07645.15 RUS75359.1 - 1.4e-09 38.0 6.2 1.4e-09 38.0 6.2 4.8 4 0 0 4 4 4 1 Calcium-binding EGF domain VWD PF00094.25 RUS75359.1 - 1.7e-06 28.4 0.1 5.2e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain TIL PF01826.17 RUS75359.1 - 7.4e-05 22.9 15.9 7.4e-05 22.9 15.9 5.0 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 RUS75359.1 - 0.0043 17.2 4.0 0.0043 17.2 4.0 5.7 6 1 0 6 6 6 2 EGF domain VP_N-CPKC PF11475.8 RUS75359.1 - 0.051 13.5 0.2 0.21 11.5 0.2 2.1 1 0 0 1 1 1 0 Virion protein N terminal domain Mucin2_WxxW PF13330.6 RUS75361.1 - 1.2e-06 29.3 1.0 2.6e-06 28.2 1.0 1.6 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region EGF PF00008.27 RUS75361.1 - 7.4e-06 26.2 1.7 7.4e-06 26.2 1.7 3.2 3 0 0 3 3 3 1 EGF-like domain VWD PF00094.25 RUS75361.1 - 5.9e-05 23.4 0.5 0.00013 22.3 0.5 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain Plasmod_Pvs28 PF06247.11 RUS75361.1 - 0.024 14.9 0.4 0.024 14.9 0.4 3.0 2 2 1 3 3 3 0 Pvs28 EGF domain hEGF PF12661.7 RUS75361.1 - 0.027 15.1 5.4 0.027 15.1 5.4 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Lectin_C PF00059.21 RUS75361.1 - 0.028 15.2 1.8 0.058 14.1 0.1 2.2 2 0 0 2 2 2 0 Lectin C-type domain VWD PF00094.25 RUS75362.1 - 7.9e-23 81.5 0.4 2e-22 80.2 0.4 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain TIL PF01826.17 RUS75362.1 - 4e-07 30.2 14.1 4e-07 30.2 14.1 6.0 6 2 1 7 7 7 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 RUS75362.1 - 0.00026 21.1 6.7 0.00026 21.1 6.7 5.1 5 0 0 5 5 5 1 EGF domain cEGF PF12662.7 RUS75362.1 - 0.012 15.5 4.6 0.012 15.5 4.6 3.9 3 0 0 3 3 3 0 Complement Clr-like EGF-like ZFYVE21_C PF16696.5 RUS75362.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus EGF_MSP1_1 PF12946.7 RUS75362.1 - 6.3 6.9 17.4 0.096 12.8 2.3 4.9 5 0 0 5 5 5 0 MSP1 EGF domain 1 MEF2_binding PF09047.10 RUS75364.1 - 7.2e-07 28.9 19.5 12 5.8 0.0 11.4 3 3 10 13 13 13 7 MEF2 binding Pacifastin_I PF05375.13 RUS75364.1 - 0.1 12.3 2.4 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) CD20 PF04103.15 RUS75365.1 - 0.68 10.0 17.4 0.7 10.0 8.2 2.7 1 1 2 3 3 3 0 CD20-like family Tetraspanin PF00335.20 RUS75366.1 - 2.2e-31 109.4 13.7 3e-31 108.9 13.7 1.2 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 RUS75367.1 - 9.9e-14 51.6 5.1 2.8e-13 50.1 4.8 1.7 1 1 1 2 2 2 1 Tetraspanin family DUF2207 PF09972.9 RUS75367.1 - 0.91 8.2 3.9 2.2 7.0 0.0 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) S-methyl_trans PF02574.16 RUS75368.1 - 9.1e-37 127.3 0.0 1.1e-36 127.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AP_endonuc_2 PF01261.24 RUS75368.1 - 0.027 13.9 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Peptidase_M17 PF00883.21 RUS75369.1 - 1.5e-63 215.0 0.1 1.6e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17 PF00883.21 RUS75371.1 - 1.2e-68 231.7 0.8 1.9e-68 231.1 0.8 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Lactamase_B_3 PF13483.6 RUS75372.1 - 7.6e-10 38.9 0.1 1.2e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 RUS75372.1 - 3.5e-08 33.2 0.2 1.2e-07 31.5 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 RUS75373.1 - 1.4e-38 132.5 0.0 2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS75373.1 - 5e-10 39.5 0.0 7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RUS75373.1 - 0.052 13.5 0.3 0.51 10.3 0.0 2.3 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily M20_dimer PF07687.14 RUS75374.1 - 3.6e-13 49.4 0.0 6.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 RUS75374.1 - 2.4e-11 43.7 1.8 9.9e-11 41.7 1.8 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 RUS75375.1 - 1.4e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RUS75375.1 - 5.6e-06 26.2 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RUS75375.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF3640 PF12342.8 RUS75375.1 - 1.4 8.7 3.1 28 4.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) DUF3439 PF11921.8 RUS75376.1 - 0.027 14.4 3.8 0.045 13.7 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TMEM154 PF15102.6 RUS75376.1 - 0.46 10.4 2.8 0.68 9.8 2.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family IFRD PF05004.13 RUS75377.1 - 2.4e-86 289.6 5.1 3.3e-86 289.2 5.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 RUS75377.1 - 2.1e-17 63.4 4.8 1.1e-16 61.2 0.8 2.4 2 0 0 2 2 2 1 Interferon-related protein conserved region DUF3069 PF11269.8 RUS75377.1 - 0.095 13.0 1.7 0.13 12.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) HEAT_EZ PF13513.6 RUS75377.1 - 0.73 10.4 5.7 0.75 10.4 1.5 2.8 2 1 0 2 2 2 0 HEAT-like repeat Pkinase PF00069.25 RUS75378.1 - 1.9e-35 122.5 0.0 5.9e-35 120.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75378.1 - 3.8e-34 118.1 0.0 8e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS75378.1 - 7.3e-07 28.3 0.3 1.1e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 RUS75378.1 - 0.0068 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS75378.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS75378.1 - 0.032 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CsgA PF17334.2 RUS75378.1 - 0.14 12.9 0.4 0.41 11.4 0.4 1.8 1 0 0 1 1 1 0 Minor curli fiber component A DUF465 PF04325.13 RUS75378.1 - 0.18 11.9 2.8 0.36 10.9 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF4652 PF15525.6 RUS75379.1 - 8e-06 25.8 47.0 5 6.9 0.1 10.9 1 1 12 13 13 13 13 Domain of unknown function (DUF4652) DUF2975 PF11188.8 RUS75381.1 - 0.0045 16.9 2.0 0.0055 16.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) Usp PF00582.26 RUS75382.1 - 1.3e-27 97.1 0.1 1.7e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family PQ-loop PF04193.14 RUS75383.1 - 9.4e-34 115.0 13.9 7.8e-17 60.8 2.0 2.5 2 0 0 2 2 2 2 PQ loop repeat Yip1 PF04893.17 RUS75384.1 - 1.2e-17 64.1 23.4 2.5e-17 63.1 23.4 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 RUS75384.1 - 4 5.6 10.9 5.1 5.3 10.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0728 PF15092.6 RUS75385.1 - 0.017 14.9 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 DinB_2 PF12867.7 RUS75386.1 - 8.7e-09 36.0 0.0 1.3e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 DinB superfamily FGE-sulfatase PF03781.16 RUS75386.1 - 1.7e-08 34.4 0.2 2.8e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.6 RUS75387.1 - 0.082 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_1 PF00685.27 RUS75388.1 - 2.8e-22 79.5 0.1 4.5e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS75388.1 - 3.1e-10 40.8 0.0 2.8e-06 27.9 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family DASH_Dad4 PF08650.10 RUS75388.1 - 0.13 12.3 0.3 0.39 10.7 0.3 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad4 PDCD2_C PF04194.13 RUS75389.1 - 1.3e-47 162.1 7.3 3.1e-47 160.9 2.2 2.5 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 RUS75389.1 - 1.4e-10 41.1 17.2 4.7e-10 39.4 14.6 2.6 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 RUS75389.1 - 1.2 9.3 11.8 0.12 12.5 3.1 3.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L33 PF00471.20 RUS75389.1 - 3.1 8.3 8.5 1.6 9.3 5.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L33 zf-HIT PF04438.16 RUS75389.1 - 4.6 7.2 14.9 3.1 7.8 8.9 2.9 2 0 0 2 2 2 0 HIT zinc finger Ribosomal_L7Ae PF01248.26 RUS75390.1 - 1.6e-06 27.7 0.3 2.4e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Latexin PF06907.12 RUS75390.1 - 0.14 11.6 0.1 2 7.8 0.0 2.0 1 1 1 2 2 2 0 Latexin BCAS3 PF12490.8 RUS75391.1 - 1.1e-23 84.1 0.0 1.9e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 RUS75391.1 - 0.19 12.7 8.2 38 5.4 4.4 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat Glyco_transf_11 PF01531.16 RUS75392.1 - 3e-36 125.2 0.0 5.4e-36 124.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 11 O-FucT PF10250.9 RUS75392.1 - 2.1e-05 24.4 0.2 3.9e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TDP43_N PF18694.1 RUS75393.1 - 2.6e-32 110.5 0.2 5.2e-32 109.5 0.0 1.6 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 RUS75393.1 - 6.7e-25 86.7 0.0 5.3e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS75393.1 - 4.2e-07 30.0 0.0 0.048 13.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RL PF17797.1 RUS75393.1 - 0.00033 20.5 0.0 0.0064 16.4 0.0 2.2 2 0 0 2 2 2 1 RL domain Nup35_RRM_2 PF14605.6 RUS75393.1 - 0.0082 16.1 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Aerolysin PF01117.20 RUS75395.1 - 5.4e-27 95.0 0.1 6.2e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Aerolysin toxin zf-C4 PF00105.18 RUS75396.1 - 8.9e-23 80.5 11.5 8.9e-23 80.5 11.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) 7tm_1 PF00001.21 RUS75398.1 - 8.6e-14 51.5 20.3 1.1e-13 51.2 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS75398.1 - 7.9e-08 31.9 24.4 4.8e-06 26.1 24.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS75398.1 - 1.5e-07 31.1 24.7 2.2e-07 30.5 24.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SecG PF03840.14 RUS75398.1 - 0.0035 17.4 0.8 0.0035 17.4 0.8 3.2 3 1 0 3 3 3 1 Preprotein translocase SecG subunit Srg PF02118.21 RUS75398.1 - 0.4 10.3 38.4 0.014 15.1 27.7 2.5 2 1 0 2 2 2 0 Srg family chemoreceptor WBP-1 PF11669.8 RUS75398.1 - 3.5 8.3 9.2 1.9 9.1 1.0 2.6 1 1 1 2 2 2 0 WW domain-binding protein 1 Fibrinogen_BP PF08017.11 RUS75399.1 - 0.034 12.6 0.0 0.066 11.6 0.0 1.4 1 1 0 1 1 1 0 Fibrinogen binding protein HTH_26 PF13443.6 RUS75399.1 - 0.091 13.2 0.1 42 4.7 0.0 4.0 3 1 3 6 6 6 0 Cro/C1-type HTH DNA-binding domain Mersacidin PF16934.5 RUS75400.1 - 0.72 9.7 2.6 42 4.0 0.0 4.2 2 1 0 4 4 4 0 Two-component Enterococcus faecalis cytolysin (EFC) Methyltransf_25 PF13649.6 RUS75401.1 - 3.7e-12 46.8 0.0 1e-11 45.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS75401.1 - 4.6e-11 43.2 0.0 1.5e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 RUS75401.1 - 2.7e-06 27.3 0.4 1.6e-05 24.7 0.4 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RUS75401.1 - 4.4e-06 26.2 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS75401.1 - 5.2e-06 26.4 0.0 1.2e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS75401.1 - 0.00037 20.3 0.0 0.00067 19.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS75401.1 - 0.003 18.3 0.0 0.0051 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 RUS75401.1 - 0.071 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin ApbA_C PF08546.11 RUS75401.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal WW PF00397.26 RUS75403.1 - 2.5e-09 37.0 0.9 8.1e-09 35.4 0.9 1.9 1 0 0 1 1 1 1 WW domain wnt PF00110.19 RUS75404.1 - 9e-80 268.5 20.8 1.6e-79 267.7 20.8 1.4 1 1 0 1 1 1 1 wnt family PAXIP1_C PF15364.6 RUS75407.1 - 1.4e-26 93.4 0.1 4e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Pkinase PF00069.25 RUS75409.1 - 1.2e-69 234.6 0.0 1.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75409.1 - 3.6e-36 124.8 0.1 5.9e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS75409.1 - 0.0011 18.9 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS75409.1 - 0.0016 17.4 0.9 0.0038 16.2 0.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS75409.1 - 0.011 15.1 0.1 0.28 10.5 0.0 2.4 1 1 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 RUS75409.1 - 0.042 13.4 0.0 0.091 12.3 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 RUS75409.1 - 0.11 11.8 0.2 0.19 11.1 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LpxI_C PF06230.11 RUS75410.1 - 0.054 13.3 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 LpxI C-terminal domain GET2 PF08690.10 RUS75411.1 - 0.00011 22.0 3.5 0.43 10.2 0.1 3.0 1 1 0 2 2 2 2 GET complex subunit GET2 DRTGG PF07085.12 RUS75411.1 - 0.029 14.1 2.0 0.89 9.4 0.1 2.3 1 1 1 2 2 2 0 DRTGG domain Rol_Rep_N PF18106.1 RUS75411.1 - 0.34 11.3 14.4 3.3 8.1 0.6 3.7 1 1 3 4 4 4 0 Rolling Circle replication initiation protein N-terminal domain U71 PF17474.2 RUS75411.1 - 0.36 10.8 2.6 21 5.1 0.1 2.9 2 1 1 3 3 3 0 Tegument protein UL11 homolog SDA1 PF05285.12 RUS75414.1 - 0.0027 17.2 30.4 0.0035 16.8 30.4 1.2 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 RUS75414.1 - 0.3 9.8 8.3 0.34 9.7 8.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Drc1-Sld2 PF11719.8 RUS75414.1 - 0.43 10.1 10.3 0.5 9.8 10.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DHC_N1 PF08385.12 RUS75415.1 - 1.1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AIF-MLS PF14962.6 RUS75415.1 - 0.037 14.0 1.9 0.078 12.9 1.9 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DASH_Ask1 PF08655.10 RUS75415.1 - 0.21 11.5 0.8 14 5.6 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Ask1 DHC_N2 PF08393.13 RUS75416.1 - 2.7e-119 398.8 11.2 2.7e-119 398.8 4.9 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Plasmid_RAQPRD PF09686.10 RUS75416.1 - 0.013 15.6 0.0 0.25 11.6 0.0 2.9 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Sec2p PF06428.11 RUS75416.1 - 0.12 12.3 1.4 0.61 10.1 0.1 2.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.12 RUS75416.1 - 1.9 9.0 8.7 14 6.2 0.1 4.9 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 RUS75416.1 - 7 6.5 6.9 8.2 6.3 0.2 4.0 3 1 1 4 4 4 0 Sec34-like family AAA_6 PF12774.7 RUS75417.1 - 1.8e-36 125.8 7.0 9.2e-17 61.0 0.4 3.4 2 1 1 3 3 3 3 Hydrolytic ATP binding site of dynein motor region Taeniidae_ag PF05596.11 RUS75417.1 - 0.054 13.5 0.5 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Taeniidae antigen AAA_7 PF12775.7 RUS75418.1 - 4e-71 238.3 0.1 3.7e-70 235.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_8 PF12780.7 RUS75418.1 - 1.5e-34 119.5 0.1 2.4e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 RUS75418.1 - 3e-22 79.1 0.0 8.6e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RUS75418.1 - 1.6e-15 57.1 0.0 1.8e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RUS75418.1 - 2.6e-12 46.9 0.0 0.00023 21.2 0.0 3.3 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS75418.1 - 0.0015 18.8 0.5 0.054 13.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 RUS75418.1 - 0.13 12.6 2.9 3.9 7.8 0.2 3.3 2 2 1 3 3 3 0 AAA ATPase domain AAA_9 PF12781.7 RUS75419.1 - 3.8e-83 277.9 0.3 3.8e-83 277.9 0.3 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 RUS75419.1 - 2e-49 168.3 0.0 4.5e-49 167.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 RUS75419.1 - 2.5e-47 161.6 10.2 3.5e-47 161.1 10.2 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF3481 PF11980.8 RUS75419.1 - 0.00039 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein CCDC144C PF14915.6 RUS75419.1 - 0.017 14.3 18.5 0.024 13.7 2.2 2.6 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region Med12 PF09497.10 RUS75419.1 - 0.026 14.8 0.8 33 4.9 0.0 3.9 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 DUF3287 PF11690.8 RUS75419.1 - 0.18 11.6 0.9 1.1 9.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Fez1 PF06818.15 RUS75419.1 - 0.38 11.2 8.6 2.6 8.4 0.3 3.0 3 0 0 3 3 3 0 Fez1 CCDC-167 PF15188.6 RUS75419.1 - 7.9 6.9 13.6 10 6.6 6.2 3.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Dynein_C PF18199.1 RUS75420.1 - 4.9e-85 285.4 0.8 3.6e-84 282.6 0.1 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RUS75420.1 - 2.2e-53 180.4 0.2 3.8e-53 179.7 0.2 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RUS75420.1 - 1.6e-43 147.6 0.0 5.3e-43 145.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Coq4 PF05019.13 RUS75421.1 - 0.035 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 THOC7 PF05615.13 RUS75421.1 - 0.23 11.8 2.5 0.48 10.7 2.5 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 Arm PF00514.23 RUS75422.1 - 6.5e-17 60.9 23.6 0.03 14.4 0.2 9.6 12 0 0 12 12 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS75422.1 - 1.1e-11 45.0 9.9 0.0011 19.3 1.0 6.3 5 2 1 6 6 6 3 HEAT repeats HEAT PF02985.22 RUS75422.1 - 8.5e-08 31.8 10.7 0.35 11.3 0.0 7.8 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.6 RUS75422.1 - 0.00058 20.3 11.4 0.3 11.6 0.1 6.4 5 1 1 6 6 6 1 HEAT-like repeat V-ATPase_H_C PF11698.8 RUS75422.1 - 0.00083 19.5 10.2 0.86 9.7 0.6 5.1 4 2 2 6 6 6 2 V-ATPase subunit H Ins_allergen_rp PF06757.13 RUS75422.1 - 0.0046 17.0 0.3 0.047 13.7 0.1 2.5 2 1 0 2 2 2 1 Insect allergen related repeat, nitrile-specifier detoxification Ank_2 PF12796.7 RUS75422.1 - 0.0056 17.3 3.9 0.0072 16.9 0.0 3.3 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) Atx10homo_assoc PF09759.9 RUS75422.1 - 0.011 15.7 5.5 1.2 9.2 1.1 4.5 2 2 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 RUS75422.1 - 0.031 14.5 2.7 0.15 12.3 0.1 3.5 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Ank_4 PF13637.6 RUS75422.1 - 0.14 12.7 0.0 29 5.4 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cnd3 PF12719.7 RUS75422.1 - 0.17 11.0 4.6 8 5.6 0.8 3.5 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 RUS75422.1 - 0.25 11.5 5.9 3.2 8.0 0.0 4.2 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 RUS75422.1 - 0.33 10.9 12.9 8.1 6.4 5.1 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.14 RUS75422.1 - 0.42 9.9 12.1 2.6 7.2 1.9 3.6 2 1 1 3 3 3 0 V-ATPase subunit H Vps39_1 PF10366.9 RUS75422.1 - 0.43 10.9 1.9 22 5.4 0.9 3.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF4704 PF15787.5 RUS75422.1 - 1.1 8.5 9.7 2.1 7.5 1.2 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF4704) Ank_2 PF12796.7 RUS75423.1 - 4.4e-65 216.3 8.3 3.6e-12 46.7 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 RUS75423.1 - 1.7e-62 205.3 12.7 7.7e-08 32.5 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 RUS75423.1 - 6.2e-62 205.2 19.4 4.5e-09 36.7 0.0 8.8 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75423.1 - 1.2e-51 166.6 8.9 5.8e-05 23.2 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 RUS75423.1 - 1.6e-46 155.8 15.0 5.1e-08 33.0 0.0 8.4 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Nepo_coat_C PF03688.14 RUS75423.1 - 1.8e-05 24.7 0.3 0.00039 20.3 0.1 2.3 2 0 0 2 2 2 1 Nepovirus coat protein, C-terminal domain DUF249 PF03158.13 RUS75423.1 - 0.2 11.4 2.3 15 5.2 0.2 3.3 3 1 0 3 3 3 0 Multigene family 530 protein MG2 PF01835.19 RUS75424.1 - 7.8e-06 26.3 0.0 0.0046 17.4 0.0 2.2 2 0 0 2 2 2 2 MG2 domain TED_complement PF07678.14 RUS75425.1 - 2.6e-54 184.4 0.1 3.4e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 RUS75425.1 - 4.3e-19 69.0 0.6 1.8e-18 67.0 0.1 2.3 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M PF00207.22 RUS75425.1 - 1.1e-14 54.0 0.0 2.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 RUS75425.1 - 2.7e-14 53.7 0.5 2e-13 50.9 0.2 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG4 PF17789.1 RUS75425.1 - 0.0011 19.0 0.0 0.0067 16.6 0.1 2.2 2 0 0 2 2 2 1 Macroglobulin domain MG4 FAM92 PF06730.11 RUS75426.1 - 5.4e-63 212.4 8.7 7.1e-63 212.0 8.7 1.1 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 RUS75426.1 - 8e-06 25.6 13.5 0.00014 21.5 13.5 2.1 1 1 0 1 1 1 1 Vps5 C terminal like BAR_3 PF16746.5 RUS75426.1 - 0.00016 21.5 13.1 0.00029 20.6 13.1 1.4 1 1 0 1 1 1 1 BAR domain of APPL family LMBR1 PF04791.16 RUS75426.1 - 0.46 9.3 4.3 0.56 9.0 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 RUS75426.1 - 1.3 9.1 14.0 0.44 10.6 7.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein NOA36 PF06524.12 RUS75426.1 - 6.4 6.0 10.6 0.4 10.0 5.1 1.8 2 0 0 2 2 2 0 NOA36 protein CENP-T_C PF15511.6 RUS75427.1 - 7.5e-22 77.5 0.2 1.7e-21 76.4 0.2 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RUS75427.1 - 0.0021 18.4 0.2 0.0067 16.8 0.2 1.8 1 0 0 1 1 1 1 CENP-S protein BslA PF17735.1 RUS75427.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 Biofilm surface layer A RBFA PF02033.18 RUS75428.1 - 4.7e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Ribosome-binding factor A Ribosomal_L3 PF00297.22 RUS75429.1 - 3.4e-18 65.8 3.2 6.3e-18 64.9 3.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L3 PEPCK_GTP PF00821.18 RUS75430.1 - 2.3e-164 546.4 0.4 2.9e-164 546.1 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 RUS75430.1 - 1.4e-93 312.6 0.0 1.9e-93 312.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Cyt-b5 PF00173.28 RUS75431.1 - 2.3e-24 85.3 0.3 2.9e-24 85.0 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_4 PF13894.6 RUS75432.1 - 2.5e-53 174.1 152.9 0.0047 17.6 1.0 25.2 25 0 0 25 25 25 19 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS75432.1 - 1.4e-48 160.7 148.5 0.00027 21.2 1.2 24.5 24 0 0 24 24 24 19 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS75432.1 - 1.2e-14 53.8 150.4 9e-06 25.6 2.5 22.6 24 0 0 24 24 24 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS75432.1 - 7e-13 48.5 117.6 0.027 14.7 0.9 20.7 23 0 0 23 23 23 10 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS75432.1 - 3.6e-08 33.5 131.3 0.0074 16.7 0.1 23.2 24 1 0 24 24 24 8 Zinc-finger double domain zf-met PF12874.7 RUS75432.1 - 0.00026 21.3 1.0 0.017 15.5 0.3 21.1 24 0 0 24 24 24 10 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS75432.1 - 0.00074 19.8 130.5 2.9 8.3 0.5 19.9 5 4 14 20 20 20 7 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 RUS75432.1 - 0.0011 19.2 4.5 0.0011 19.2 4.5 14.7 8 5 8 17 17 17 8 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RUS75432.1 - 0.017 14.9 1.2 0.017 14.9 1.2 15.8 17 0 0 17 17 17 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RUS75432.1 - 0.21 11.5 0.1 0.21 11.5 0.1 13.6 16 0 0 16 16 16 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 RUS75433.1 - 1.4e-17 62.8 32.4 6.1e-05 23.5 1.9 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS75433.1 - 5.8e-17 61.1 35.6 5.6e-06 26.5 4.0 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS75433.1 - 9.6e-09 35.3 27.0 0.014 15.8 1.4 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-Di19 PF05605.12 RUS75433.1 - 1.4e-07 31.7 19.3 0.0043 17.3 3.4 3.4 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RUS75433.1 - 1.9e-07 30.9 28.8 0.0069 16.4 2.5 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS75433.1 - 1.4e-06 28.4 21.6 0.055 13.8 0.2 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 RUS75433.1 - 3.4e-05 23.6 7.2 0.12 12.3 0.2 3.5 2 1 1 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 RUS75433.1 - 0.0002 22.1 12.3 0.0064 17.2 0.7 3.2 1 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 RUS75433.1 - 0.0018 18.6 22.4 0.063 13.7 0.8 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 RUS75433.1 - 0.0025 18.2 5.0 3.3 8.2 0.1 4.0 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain DUF1644 PF07800.12 RUS75433.1 - 0.012 15.7 3.7 0.012 15.7 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Rad50_zn_hook PF04423.14 RUS75433.1 - 0.021 14.7 5.7 0.85 9.5 0.7 2.8 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 RUS75433.1 - 0.054 13.8 24.0 0.25 11.7 1.1 4.4 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-WRNIP1_ubi PF18279.1 RUS75433.1 - 0.079 13.6 8.0 0.1 13.3 0.4 3.4 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn_ribbon_SprT PF17283.2 RUS75433.1 - 0.096 12.6 18.5 0.52 10.3 0.1 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF2225 PF09986.9 RUS75433.1 - 0.23 11.2 0.1 0.23 11.2 0.1 3.4 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_7 PF15269.6 RUS75433.1 - 0.32 11.1 0.2 0.32 11.1 0.2 3.7 2 1 1 4 4 4 0 Zinc-finger CcmH PF03918.14 RUS75433.1 - 0.37 10.1 1.5 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF1178 PF06676.11 RUS75433.1 - 0.39 11.1 9.6 0.045 14.1 1.3 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1178) zf-3CxxC_2 PF17180.4 RUS75433.1 - 0.48 11.2 0.1 0.48 11.2 0.1 3.8 3 2 0 3 3 2 0 Zinc-binding domain Actin_micro PF17003.5 RUS75433.1 - 0.84 8.8 9.8 7.2 5.7 4.3 2.9 1 1 1 2 2 2 0 Putative actin-like family Prok-RING_1 PF14446.6 RUS75433.1 - 2.3 8.2 13.2 10 6.1 0.2 4.5 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 UBZ_FAAP20 PF15750.5 RUS75433.1 - 2.9 7.9 5.6 13 5.9 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger CpXC PF14353.6 RUS75433.1 - 3.3 7.8 11.9 0.61 10.1 0.9 3.2 2 1 0 3 3 3 0 CpXC protein zf-RING_4 PF14570.6 RUS75433.1 - 4 7.3 10.1 1.6 8.5 2.1 3.3 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 RUS75433.1 - 5.2 7.2 9.6 6.5 6.9 0.7 3.5 3 1 0 3 3 3 0 RING-type zinc-finger C1_4 PF07975.12 RUS75433.1 - 6.7 7.0 18.2 11 6.4 0.2 4.4 1 1 2 4 4 4 0 TFIIH C1-like domain zf_C2H2_ZHX PF18387.1 RUS75433.1 - 6.9 6.4 8.6 19 5.0 0.1 3.6 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RUS75433.1 - 9.3 6.1 20.4 3.3 7.5 1.8 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-met PF12874.7 RUS75435.1 - 0.0095 16.3 0.2 0.024 15.0 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 RUS75435.1 - 0.041 13.9 0.4 0.079 13.0 0.4 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C2H2_4 PF13894.6 RUS75435.1 - 0.14 13.1 0.2 0.33 11.9 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF218 PF02698.17 RUS75436.1 - 2.1e-22 79.5 0.0 3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain MCM PF00493.23 RUS75437.1 - 7.5e-79 263.9 0.0 1.1e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 RUS75437.1 - 5.3e-27 94.1 1.5 9.9e-27 93.2 1.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RUS75437.1 - 3.8e-11 42.8 0.1 2.5e-07 30.3 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS75437.1 - 3.3e-09 36.9 0.0 9.6e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RUS75437.1 - 9.6e-06 25.5 0.0 2.5e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS75437.1 - 0.0004 20.1 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 RUS75437.1 - 0.0016 18.8 0.3 0.012 16.0 0.0 2.3 2 1 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RUS75437.1 - 0.0037 16.7 0.4 0.009 15.4 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 RUS75437.1 - 0.0049 17.1 0.2 0.041 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 RUS75437.1 - 0.0059 17.0 0.1 0.036 14.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RUS75437.1 - 0.025 14.5 0.1 3.2 7.6 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 RUS75437.1 - 0.045 14.1 0.1 6.6 7.1 0.0 2.7 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 RUS75437.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 RUS75437.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain M157 PF11624.8 RUS75438.1 - 8.6e-05 22.0 1.3 0.26 10.6 0.1 2.4 2 0 0 2 2 2 2 MHC class I-like protein M157 RA PF00788.23 RUS75438.1 - 0.0029 18.2 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF4349 PF14257.6 RUS75438.1 - 0.91 8.9 8.6 6.5 6.1 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) RecG_N PF17190.4 RUS75438.1 - 0.97 10.2 4.5 30 5.4 0.4 2.8 2 0 0 2 2 2 0 RecG N-terminal helical domain IBN_N PF03810.19 RUS75439.1 - 2.1e-18 66.0 0.0 3.7e-16 58.8 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RUS75439.1 - 0.00012 22.1 4.9 0.0019 18.3 0.0 4.4 4 2 2 6 6 6 1 Exportin 1-like protein Cse1 PF08506.10 RUS75439.1 - 0.0046 15.8 2.3 0.0068 15.3 0.2 2.4 3 0 0 3 3 3 1 Cse1 HEAT_2 PF13646.6 RUS75439.1 - 0.023 15.1 0.1 0.91 10.0 0.0 3.6 4 1 1 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 RUS75439.1 - 0.047 13.9 0.2 9.6 6.4 0.1 3.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 RUS75439.1 - 0.56 10.8 4.0 3.8 8.1 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Glyco_hydro_18 PF00704.28 RUS75440.1 - 1.5e-51 176.0 0.1 1e-25 91.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 VHP PF02209.19 RUS75440.1 - 0.013 15.6 0.1 0.032 14.3 0.1 1.7 1 0 0 1 1 1 0 Villin headpiece domain Aph-1 PF06105.12 RUS75441.1 - 6.3e-90 300.6 19.4 7.2e-90 300.4 19.4 1.0 1 0 0 1 1 1 1 Aph-1 protein Rad21_Rec8 PF04824.16 RUS75441.1 - 0.063 12.6 0.3 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Conserved region of Rad21 / Rec8 like protein CLIP_SPH_mas PF18398.1 RUS75442.1 - 1.6e-06 28.4 32.4 9.7 6.7 0.5 9.6 1 1 8 9 9 9 8 Clip-domain serine protease homolog masquerade DUF5548 PF17702.1 RUS75442.1 - 0.62 9.8 10.1 12 5.6 1.4 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5548) DUF2798 PF11391.8 RUS75442.1 - 3.4 7.8 26.1 42 4.3 0.3 5.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2798) EGF_CA PF07645.15 RUS75443.1 - 4.4e-94 308.5 148.6 5.8e-11 42.4 4.3 10.3 10 0 0 10 10 10 10 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 RUS75443.1 - 2.7e-63 209.7 110.4 1.1e-07 31.8 1.7 10.5 10 0 0 10 10 10 10 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 RUS75443.1 - 9e-46 153.9 122.1 1.9e-06 28.1 6.2 10.5 9 1 1 10 10 10 9 Pvs28 EGF domain cEGF PF12662.7 RUS75443.1 - 4.1e-42 141.7 90.4 3.3e-05 23.7 0.7 11.9 11 0 0 11 11 11 10 Complement Clr-like EGF-like EGF PF00008.27 RUS75443.1 - 7e-33 112.5 116.0 2.7e-06 27.6 2.2 12.6 10 5 0 10 10 10 10 EGF-like domain FXa_inhibition PF14670.6 RUS75443.1 - 1.1e-27 96.0 118.3 0.00039 20.6 4.2 11.4 6 3 4 10 10 10 10 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 RUS75443.1 - 6.9e-27 93.4 155.6 0.0006 20.0 4.6 14.4 7 4 7 15 15 15 10 EGF domain hEGF PF12661.7 RUS75443.1 - 4.9e-26 90.4 157.3 0.00018 22.0 7.2 13.5 15 0 0 15 15 12 10 Human growth factor-like EGF EB PF01683.18 RUS75443.1 - 1.1e-05 25.6 138.3 0.28 11.5 9.1 10.8 3 3 7 10 10 10 7 EB module EGF_2 PF07974.13 RUS75443.1 - 0.024 15.0 116.7 0.041 14.3 7.2 11.0 10 0 0 10 10 10 0 EGF-like domain PLD_C PF12357.8 RUS75443.1 - 0.074 13.0 20.9 54 3.8 0.1 8.5 9 0 0 9 9 9 0 Phospholipase D C terminal AF-4 PF05110.13 RUS75444.1 - 0.7 7.9 36.6 0.94 7.5 36.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 RUS75444.1 - 3 6.2 24.9 3.3 6.1 24.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Homeodomain PF00046.29 RUS75445.1 - 1.4e-20 72.8 0.7 1.6e-20 72.7 0.7 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS75445.1 - 0.0013 18.6 0.2 0.0015 18.3 0.2 1.2 1 0 0 1 1 1 1 Homeobox KN domain BAR_3_WASP_bdg PF10456.9 RUS75446.1 - 7.8e-80 267.7 2.1 1.1e-79 267.3 2.1 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 RUS75446.1 - 4.9e-11 42.1 0.2 4.9e-11 42.1 0.2 2.5 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 RUS75446.1 - 9e-11 41.5 0.2 1.7e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS75446.1 - 6.6e-09 35.3 0.1 1.4e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 RUS75446.1 - 2.9e-08 33.6 0.2 2.6e-05 23.9 1.6 2.6 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 RUS75446.1 - 5.7e-06 26.3 3.2 7.4e-06 25.9 0.8 2.5 2 1 0 2 2 2 1 PX domain CD225 PF04505.12 RUS75447.1 - 2.2e-11 43.7 0.7 3.1e-11 43.2 0.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4199 PF13858.6 RUS75447.1 - 0.015 15.7 1.3 0.019 15.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3671 PF12420.8 RUS75447.1 - 0.11 12.5 1.5 0.17 11.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function SDA1 PF05285.12 RUS75449.1 - 0.00046 19.7 27.8 0.00046 19.7 27.8 2.1 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 RUS75449.1 - 0.00093 17.6 59.8 0.0017 16.7 32.6 2.0 2 0 0 2 2 2 2 Nop14-like family Merozoite_SPAM PF07133.11 RUS75449.1 - 0.0014 18.7 59.9 0.0014 18.7 59.9 2.1 2 0 0 2 2 1 1 Merozoite surface protein (SPAM) Mpp10 PF04006.12 RUS75449.1 - 0.0037 15.8 31.2 0.0037 15.8 31.2 2.0 2 0 0 2 2 2 1 Mpp10 protein DNA_pol_phi PF04931.13 RUS75449.1 - 0.0058 14.8 81.1 0.035 12.2 40.8 2.0 2 0 0 2 2 2 2 DNA polymerase phi DDHD PF02862.17 RUS75449.1 - 0.006 16.8 2.2 0.0061 16.8 2.2 1.2 1 0 0 1 1 1 1 DDHD domain Plasmodium_Vir PF05795.11 RUS75449.1 - 0.0086 15.5 9.8 0.012 15.1 9.8 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF4045 PF13254.6 RUS75449.1 - 0.02 14.5 8.4 0.024 14.3 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 RUS75449.1 - 0.057 13.6 14.5 0.079 13.1 14.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CPSF100_C PF13299.6 RUS75449.1 - 0.099 12.8 17.8 0.13 12.4 13.1 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S64 PF08192.11 RUS75449.1 - 0.12 10.9 4.1 0.12 10.9 4.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 RUS75449.1 - 0.24 10.1 13.7 0.33 9.7 13.7 1.2 1 0 0 1 1 1 0 Presenilin DUF3292 PF11696.8 RUS75449.1 - 0.46 8.8 4.4 0.46 8.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CobT PF06213.12 RUS75449.1 - 0.6 9.4 58.3 0.068 12.6 32.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF2151 PF10221.9 RUS75449.1 - 0.67 8.5 11.2 0.99 7.9 11.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Neur_chan_memb PF02932.16 RUS75449.1 - 0.98 9.4 2.6 1 9.3 2.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 RUS75449.1 - 1 7.4 10.7 1.1 7.3 10.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.8 RUS75449.1 - 2.5 8.2 9.9 3.3 7.8 9.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SpoIIP PF07454.11 RUS75449.1 - 2.7 7.4 21.6 0.24 10.8 16.7 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 RUS75449.1 - 3.3 6.6 10.0 4.4 6.2 10.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 RUS75449.1 - 4.5 7.2 32.0 0.58 10.1 23.9 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Vfa1 PF08432.10 RUS75449.1 - 4.7 7.5 30.7 4.1 7.7 21.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AIF_C PF14721.6 RUS75449.1 - 4.8 7.5 11.3 11 6.4 11.3 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 RUS75449.1 - 5.3 6.7 15.4 8.1 6.1 15.4 1.3 1 0 0 1 1 1 0 Connexin MCM_bind PF09739.9 RUS75449.1 - 5.5 5.3 13.0 7.9 4.8 13.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 RUS75449.1 - 5.7 6.6 11.7 7.4 6.3 11.7 1.1 1 0 0 1 1 1 0 AAA domain OstA_2 PF13100.6 RUS75450.1 - 0.094 12.3 0.5 1.1 8.8 0.3 2.3 1 1 1 2 2 2 0 OstA-like protein Sec10 PF07393.11 RUS75451.1 - 0.0027 16.2 0.1 0.0031 16.0 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 RUS75451.1 - 0.0029 16.6 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DIL PF01843.19 RUS75451.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 DIL domain RNase_PH PF01138.21 RUS75452.1 - 6.7e-35 120.5 0.0 8.9e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS75452.1 - 0.0045 17.0 0.1 0.0096 15.9 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TAFH PF07531.14 RUS75453.1 - 2e-33 114.3 0.8 4.1e-33 113.3 0.8 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.11 RUS75453.1 - 1.3e-17 63.3 2.5 3.1e-17 62.1 2.5 1.6 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.18 RUS75453.1 - 2.1e-07 30.9 17.5 4.1e-07 30.0 17.5 1.5 1 0 0 1 1 1 1 MYND finger P4Ha_N PF08336.11 RUS75453.1 - 6.4 6.8 8.6 0.36 10.8 0.9 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2512 PF10710.9 RUS75454.1 - 0.093 12.4 0.4 0.093 12.4 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Dpy-30 PF05186.13 RUS75455.1 - 2.5e-10 39.9 0.5 1.7e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 Dpy-30 motif Dpy-30 PF05186.13 RUS75457.1 - 2.4e-09 36.7 1.4 7.2e-09 35.2 0.3 2.1 2 0 0 2 2 2 1 Dpy-30 motif Dpy-30 PF05186.13 RUS75458.1 - 7.9e-12 44.7 0.6 3.1e-11 42.8 0.1 2.1 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.17 RUS75458.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Spectrin_like PF18373.1 RUS75458.1 - 0.048 13.7 2.3 0.12 12.5 0.1 2.6 2 0 0 2 2 2 0 Spectrin like domain Dpy-30 PF05186.13 RUS75459.1 - 2e-09 37.0 0.5 6.1e-09 35.4 0.2 1.9 2 0 0 2 2 2 1 Dpy-30 motif GMC_oxred_N PF00732.19 RUS75460.1 - 4e-98 328.4 0.0 5.6e-98 328.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RUS75460.1 - 5.1e-39 134.1 0.0 9.3e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase HAD_2 PF13419.6 RUS75460.1 - 4.1e-34 118.2 0.0 1.9e-16 60.7 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS75460.1 - 4.5e-30 105.5 0.8 5.7e-15 56.2 0.1 4.4 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS75460.1 - 1.5e-19 69.9 1.1 1.3e-08 34.7 0.4 2.8 2 0 0 2 2 2 2 HAD-hyrolase-like HAD PF12710.7 RUS75460.1 - 2.1e-08 34.8 0.0 0.0019 18.7 0.0 3.1 2 2 0 2 2 2 2 haloacid dehalogenase-like hydrolase DAO PF01266.24 RUS75460.1 - 0.00033 20.4 0.0 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Hydrolase_3 PF08282.12 RUS75460.1 - 0.00037 20.3 1.7 1.2 8.8 0.0 4.1 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Lycopene_cycl PF05834.12 RUS75460.1 - 0.00051 19.2 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 RUS75460.1 - 0.0011 19.1 0.1 0.0035 17.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS75460.1 - 0.0024 17.0 0.0 0.0097 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS75460.1 - 0.013 14.8 0.0 0.047 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS75460.1 - 0.015 14.6 0.0 0.5 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hydrolase_6 PF13344.6 RUS75460.1 - 0.048 13.8 0.0 3.1 8.0 0.0 3.5 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase ApbA PF02558.16 RUS75460.1 - 0.072 12.7 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 RUS75460.1 - 0.14 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain EF-hand_1 PF00036.32 RUS75461.1 - 4e-33 110.5 10.2 9.4e-08 31.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RUS75461.1 - 1.5e-28 96.2 6.9 5e-09 35.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS75461.1 - 2.2e-27 93.3 7.9 3.3e-08 32.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS75461.1 - 8.6e-27 93.4 1.0 3.9e-15 56.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS75461.1 - 4.5e-22 77.7 3.1 1.1e-08 34.7 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS75461.1 - 3.5e-07 30.5 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RUS75461.1 - 7.1e-05 23.1 0.0 0.23 11.8 0.0 2.3 1 1 2 3 3 3 3 EF-hand domain EF-hand_4 PF12763.7 RUS75461.1 - 0.00012 22.0 0.3 0.34 10.9 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS75461.1 - 0.0002 21.3 0.3 0.032 14.2 0.0 2.7 1 1 0 2 2 2 1 Caleosin related protein TerB PF05099.13 RUS75461.1 - 0.0097 15.9 0.0 0.29 11.1 0.0 2.1 1 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_10 PF14788.6 RUS75461.1 - 0.019 14.9 0.7 9.9 6.1 0.0 3.4 3 1 1 4 4 4 0 EF hand Dockerin_1 PF00404.18 RUS75461.1 - 0.038 14.2 7.9 0.28 11.4 1.0 3.6 2 2 1 3 3 3 0 Dockerin type I domain HMG_box PF00505.19 RUS75462.1 - 4.8e-05 23.7 1.5 0.00011 22.6 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box T-box PF00907.22 RUS75464.1 - 3.3e-08 34.0 0.1 5.8e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 T-box TGT PF01702.18 RUS75465.1 - 3.8e-147 490.0 0.0 4.3e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase EF-hand_1 PF00036.32 RUS75468.1 - 1.4e-07 30.5 0.0 2.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS75468.1 - 2.5e-07 30.1 0.6 4.4e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 RUS75468.1 - 1.1e-06 27.8 0.0 2.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 RUS75468.1 - 1.9e-06 28.2 0.0 2.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS75468.1 - 3.9e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair Ank_4 PF13637.6 RUS75469.1 - 1.7e-15 57.2 2.5 2.2e-09 37.7 1.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75469.1 - 3.5e-12 46.7 0.1 5.1e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS75469.1 - 2.3e-11 42.8 0.2 1.9e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS75469.1 - 2.8e-11 43.4 3.8 2.9e-09 37.0 0.6 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS75469.1 - 1.4e-07 31.7 1.0 0.0061 17.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ribosomal_L5 PF00281.19 RUS75470.1 - 4.3e-11 43.0 0.0 33 4.9 0.0 8.7 1 1 11 12 12 12 9 Ribosomal protein L5 IlvB_leader PF08049.11 RUS75470.1 - 5e-07 29.5 20.9 1.4e+02 2.5 0.0 11.5 12 0 0 12 12 12 0 IlvB leader peptide DUF4112 PF13430.6 RUS75470.1 - 0.035 14.4 0.0 99 3.3 0.0 3.9 1 1 5 6 6 6 0 Domain of unknown function (DUF4112) SseC PF04888.12 RUS75471.1 - 0.014 15.0 7.2 0.015 14.9 7.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Zincin_2 PF10103.9 RUS75471.1 - 0.43 9.8 14.3 3.7 6.7 14.3 2.0 1 1 0 1 1 1 0 Zincin-like metallopeptidase Spore-coat_CotD PF11122.8 RUS75471.1 - 2.6 8.9 11.9 7.5e+02 1.0 11.9 2.4 1 1 0 1 1 1 0 Inner spore coat protein D Abhydrolase_6 PF12697.7 RUS75472.1 - 1.3e-06 29.2 0.2 0.002 18.7 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS75472.1 - 0.0007 19.3 0.1 0.034 13.8 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS75473.1 - 1.5e-11 45.4 0.0 1.2e-07 32.6 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS75473.1 - 2.7e-08 33.8 0.0 0.00011 21.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS75473.1 - 2.3e-06 27.0 0.0 0.0024 17.2 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 RUS75473.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) zf-B_box PF00643.24 RUS75474.1 - 5.3e-07 29.7 9.4 5.3e-07 29.7 9.4 4.2 4 1 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 RUS75474.1 - 2e-06 27.7 3.6 2e-06 27.7 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS75474.1 - 1.6e-05 24.6 2.5 1.6e-05 24.6 2.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS75474.1 - 3.4e-05 23.6 1.9 3.4e-05 23.6 1.9 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS75474.1 - 0.0024 17.8 1.2 0.0024 17.8 1.2 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS75474.1 - 0.017 15.4 3.6 0.017 15.4 3.6 3.4 3 0 0 3 3 3 0 Ring finger domain Tup_N PF08581.10 RUS75474.1 - 0.034 14.5 0.8 0.15 12.4 0.8 2.1 1 0 0 1 1 1 0 Tup N-terminal Dynactin_p22 PF07426.11 RUS75474.1 - 0.046 13.6 1.4 0.1 12.5 1.4 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 Biopterin_H PF00351.21 RUS75476.1 - 4.6e-120 400.6 2.3 1.4e-67 228.1 0.0 2.1 2 0 0 2 2 2 2 Biopterin-dependent aromatic amino acid hydroxylase PA26 PF04636.13 RUS75477.1 - 5.6e-179 595.7 3.3 6.9e-179 595.4 3.3 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 RUS75477.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family RhoGEF PF00621.20 RUS75478.1 - 2.2e-17 63.9 0.1 3.9e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF4347 PF14252.6 RUS75478.1 - 4.6e-10 39.6 0.0 8.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) BSP_II PF05432.11 RUS75478.1 - 0.14 11.9 16.5 0.21 11.3 16.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Dpy-30 PF05186.13 RUS75478.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif Prothymosin PF03247.14 RUS75478.1 - 2.4 8.7 26.3 4.4 7.8 26.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Mito_carr PF00153.27 RUS75479.1 - 3.1e-42 142.4 0.7 1.4e-17 63.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Atrophin-1 PF03154.15 RUS75480.1 - 0.01 14.2 7.2 0.013 13.9 7.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Abhydro_lipase PF04083.16 RUS75481.1 - 4.5e-22 77.4 0.0 1.2e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RUS75481.1 - 1.6e-16 60.8 0.1 5.5e-15 55.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS75481.1 - 2e-08 33.8 0.0 7.1e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 RUS75482.1 - 3.2e-19 68.3 0.0 7e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RUS75482.1 - 1.9e-17 63.8 0.9 4e-16 59.5 0.9 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS75482.1 - 4e-09 36.1 0.1 4.3e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 CDK2AP PF09806.9 RUS75483.1 - 4.1e-24 85.9 0.0 4.1e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein WD40 PF00400.32 RUS75484.1 - 0.00028 21.6 11.0 1.5 9.8 1.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF410 PF04190.13 RUS75485.1 - 5.1e-77 259.1 0.0 6.1e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TMEM220 PF15071.6 RUS75486.1 - 4.9e-21 75.4 0.9 4.9e-21 75.4 0.9 2.0 1 1 1 2 2 2 1 Transmembrane family 220, helix DUF2975 PF11188.8 RUS75486.1 - 0.69 9.8 6.4 1.4 8.8 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) PX PF00787.24 RUS75487.1 - 1.8e-18 66.6 1.6 2.9e-18 65.9 0.8 1.8 2 0 0 2 2 2 1 PX domain EF-hand_4 PF12763.7 RUS75487.1 - 0.024 14.6 0.0 0.092 12.7 0.0 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FAM92 PF06730.11 RUS75487.1 - 0.025 14.0 1.3 0.056 12.9 1.3 1.7 1 0 0 1 1 1 0 FAM92 protein Pkinase_Tyr PF07714.17 RUS75488.1 - 2.6e-34 118.7 0.1 5e-34 117.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS75488.1 - 1.4e-24 86.9 0.0 2.7e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 RUS75488.1 - 2.9e-06 27.8 0.1 0.0005 20.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75488.1 - 6.9e-06 26.5 0.1 2.8e-05 24.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS75488.1 - 0.0012 19.1 0.7 0.0035 17.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75488.1 - 0.0012 19.1 0.2 0.16 12.6 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat SpoIISB_antitox PF14185.6 RUS75488.1 - 0.0039 17.0 0.1 5.1 7.1 0.0 2.8 2 0 0 2 2 2 2 Antitoxin SpoIISB, type II toxin-antitoxin system Ank PF00023.30 RUS75488.1 - 0.0069 16.8 0.9 1.2 9.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SH3_1 PF00018.28 RUS75489.1 - 1.8e-32 110.7 0.2 8.2e-16 57.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 RUS75489.1 - 4.5e-27 93.6 0.1 2.4e-13 49.7 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 RUS75489.1 - 6.4e-24 83.8 0.0 1.1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 RUS75489.1 - 3.8e-23 80.9 0.0 3.1e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 RUS75489.1 - 0.00025 21.3 0.5 0.003 17.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain SH2_2 PF14633.6 RUS75489.1 - 0.0014 18.0 0.0 0.0028 17.1 0.0 1.5 1 1 0 1 1 1 1 SH2 domain hSH3 PF14603.6 RUS75489.1 - 0.022 15.2 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_10 PF17902.1 RUS75489.1 - 0.095 12.8 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 SH3 domain DUF5348 PF17295.2 RUS75489.1 - 0.11 12.4 0.2 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5348) AAA_12 PF13087.6 RUS75490.1 - 1.8e-60 204.0 0.0 2e-34 119.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 RUS75490.1 - 1e-47 163.1 2.4 3.6e-21 76.1 0.3 4.2 2 2 1 3 3 3 3 AAA domain RNB PF00773.19 RUS75490.1 - 1.7e-36 126.2 0.0 5.7e-36 124.5 0.0 2.0 1 1 0 1 1 1 1 RNB domain AAA_30 PF13604.6 RUS75490.1 - 6.6e-11 42.3 0.0 4.4e-05 23.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RUS75490.1 - 5.2e-10 39.8 2.0 0.0012 19.2 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.6 RUS75490.1 - 6e-08 33.1 0.0 0.0016 18.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 RUS75490.1 - 7.3e-06 25.7 0.0 0.045 13.3 0.0 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 RUS75490.1 - 6.2e-05 22.9 1.0 0.23 11.2 0.0 4.2 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 RUS75490.1 - 0.00014 21.9 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS75490.1 - 0.00029 21.3 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 RUS75490.1 - 0.00054 19.5 0.0 5.2 6.5 0.0 3.3 3 0 0 3 3 3 1 PhoH-like protein Helicase_RecD PF05127.14 RUS75490.1 - 0.00074 19.4 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 Helicase Mg_chelatase PF01078.21 RUS75490.1 - 0.0017 17.8 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RUS75490.1 - 0.0021 18.5 0.0 0.39 11.1 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain zf-C2H2_jaz PF12171.8 RUS75490.1 - 0.02 15.2 4.9 0.061 13.6 4.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ResIII PF04851.15 RUS75490.1 - 0.028 14.4 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 RUS75490.1 - 0.031 14.8 0.1 1.6 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RUS75490.1 - 0.044 14.2 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 RUS75490.1 - 0.055 13.4 0.0 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RUS75490.1 - 0.07 12.9 0.0 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3251 PF11622.8 RUS75490.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) AAA_28 PF13521.6 RUS75490.1 - 0.11 12.7 1.9 0.27 11.5 0.1 2.6 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 RUS75490.1 - 0.15 11.6 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 RUS75490.1 - 0.21 11.6 0.2 0.73 9.9 0.2 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-CCCH PF00642.24 RUS75490.1 - 1.9 8.5 4.6 32 4.6 0.6 3.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SRP-alpha_N PF04086.13 RUS75491.1 - 0.39 10.6 14.7 0.48 10.3 14.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.11 RUS75491.1 - 1.9 7.9 7.5 2.3 7.6 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 RUS75491.1 - 9.7 4.6 9.5 11 4.4 9.5 1.1 1 0 0 1 1 1 0 Macoilin family SET PF00856.28 RUS75492.1 - 9.1e-09 35.9 0.0 2.6e-08 34.4 0.0 1.9 1 1 1 2 2 2 1 SET domain zf-MYND PF01753.18 RUS75492.1 - 3.4e-05 23.9 17.5 0.00012 22.1 17.5 2.0 1 1 0 1 1 1 1 MYND finger Ecl1 PF12855.7 RUS75492.1 - 0.016 16.3 1.1 0.016 16.3 1.1 1.7 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Gal-3-0_sulfotr PF06990.11 RUS75493.1 - 2.4e-53 181.5 1.9 2.9e-53 181.2 1.9 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS75493.1 - 0.00025 21.0 4.4 0.00059 19.8 4.4 1.6 1 1 0 1 1 1 1 Sulfotransferase family CwfJ_C_1 PF04677.15 RUS75493.1 - 0.02 14.8 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 USP8_interact PF08941.10 RUS75495.1 - 4.8e-80 267.6 4.1 6.6e-80 267.1 4.1 1.2 1 0 0 1 1 1 1 USP8 interacting zf-C3HC4_2 PF13923.6 RUS75495.1 - 9.2e-09 35.0 10.0 2.6e-08 33.6 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS75495.1 - 1.1e-07 31.6 9.6 1.1e-07 31.6 9.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS75495.1 - 1.6e-07 31.5 10.0 5.1e-07 29.9 10.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RUS75495.1 - 1.3e-05 25.4 8.2 1.3e-05 25.4 8.2 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain U-box PF04564.15 RUS75495.1 - 5.9e-05 23.2 0.1 0.00018 21.6 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 RUS75495.1 - 8.2e-05 22.6 11.1 0.00021 21.3 11.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 RUS75495.1 - 0.00012 21.9 2.0 0.00035 20.4 2.0 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 RUS75495.1 - 0.00051 20.1 10.0 0.0015 18.6 10.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RUS75495.1 - 0.00062 19.6 6.9 0.00062 19.6 6.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 RUS75495.1 - 0.00071 20.2 1.9 0.11 13.2 1.6 2.8 1 1 1 2 2 2 1 TRAF-type zinc finger zf-RING_5 PF14634.6 RUS75495.1 - 0.00091 19.1 7.9 0.0022 17.9 6.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 RUS75495.1 - 0.0014 18.4 4.6 0.0014 18.4 4.6 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 RUS75495.1 - 0.0016 18.6 5.7 0.0052 16.9 5.7 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 Sina PF03145.16 RUS75495.1 - 0.0032 17.5 3.3 0.011 15.7 3.0 1.9 1 1 1 2 2 2 1 Seven in absentia protein family zf-ANAPC11 PF12861.7 RUS75495.1 - 0.0036 17.3 2.3 0.011 15.7 2.3 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger UvrB PF12344.8 RUS75495.1 - 0.012 15.5 0.6 0.012 15.5 0.6 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B zf-TRAF_2 PF15965.5 RUS75495.1 - 0.099 13.1 10.7 0.041 14.4 4.0 2.9 1 1 2 3 3 2 0 TRAF-like zinc-finger DUF4679 PF15728.5 RUS75495.1 - 0.1 11.6 2.1 0.17 10.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) GIDA PF01134.22 RUS75495.1 - 0.17 10.9 0.4 1.9 7.5 0.2 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A Zn_ribbon_17 PF17120.5 RUS75495.1 - 0.73 9.5 10.0 1 9.0 5.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RUS75495.1 - 1 9.3 9.2 16 5.4 9.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Fzo_mitofusin PF04799.13 RUS75495.1 - 3.9 7.0 6.3 5.6 6.5 3.9 2.0 2 0 0 2 2 2 0 fzo-like conserved region TolA_bind_tri PF16331.5 RUS75495.1 - 6.7 6.9 9.4 0.42 10.7 4.0 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Metallophos PF00149.28 RUS75496.1 - 4.7e-37 128.5 0.1 5.9e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 23S_rRNA_IVP PF05635.11 RUS75496.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein ABC_membrane PF00664.23 RUS75497.1 - 1.2e-70 238.3 31.7 1.1e-36 126.9 13.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS75497.1 - 6.5e-54 182.2 0.2 1.5e-28 100.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 RUS75497.1 - 9.4e-12 44.8 2.8 0.0005 19.6 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS75497.1 - 1.3e-05 25.2 4.4 0.085 12.9 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS75497.1 - 5e-05 23.3 0.6 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 RUS75497.1 - 0.00014 22.3 0.1 0.3 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 RUS75497.1 - 0.00019 22.0 0.5 0.41 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS75497.1 - 0.00019 21.7 0.4 1 9.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RUS75497.1 - 0.00033 20.3 0.5 0.94 9.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 RUS75497.1 - 0.00046 20.3 1.9 0.22 11.6 0.4 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain IstB_IS21 PF01695.17 RUS75497.1 - 0.0014 18.4 0.5 2.7 7.7 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.6 RUS75497.1 - 0.0028 17.4 1.2 0.6 9.8 0.1 3.0 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 RUS75497.1 - 0.0032 16.5 0.1 0.22 10.4 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 RUS75497.1 - 0.0038 17.1 1.8 0.91 9.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 RUS75497.1 - 0.0042 16.6 0.2 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 RUS75497.1 - 0.0042 16.7 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RUS75497.1 - 0.0065 16.9 1.8 0.98 9.8 0.0 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RUS75497.1 - 0.015 15.1 0.1 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 RUS75497.1 - 0.018 14.0 0.1 0.52 9.2 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain Dynamin_N PF00350.23 RUS75497.1 - 0.028 14.5 2.8 0.53 10.3 0.3 2.4 2 0 0 2 2 2 0 Dynamin family AAA_11 PF13086.6 RUS75497.1 - 0.045 13.5 0.1 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RUS75497.1 - 0.049 14.0 0.1 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 RUS75497.1 - 0.061 13.9 0.0 16 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RUS75497.1 - 0.075 13.3 0.3 27 5.0 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 RUS75497.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) cobW PF02492.19 RUS75497.1 - 0.13 11.9 1.2 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 RUS75497.1 - 0.16 11.1 0.3 8.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.29 RUS75497.1 - 0.27 11.0 0.5 6.5 6.5 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 RUS75497.1 - 0.29 11.1 1.3 32 4.5 0.0 3.3 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 RUS75497.1 - 0.57 9.4 2.0 11 5.2 0.0 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.22 RUS75499.1 - 1.1e-66 223.4 0.8 1.3e-66 223.2 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS75499.1 - 7.1e-35 119.8 0.2 1.1e-34 119.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS75499.1 - 9.1e-17 61.1 0.4 1.2e-16 60.7 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS75499.1 - 3.6e-06 26.5 0.3 4.6e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS75499.1 - 2.3e-05 23.9 0.1 2.9e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS75499.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS75499.1 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3963 PF13124.6 RUS75499.1 - 0.033 14.1 0.6 0.068 13.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) TniB PF05621.11 RUS75499.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Snf7 PF03357.21 RUS75500.1 - 1.1e-54 184.6 15.9 1.3e-54 184.4 15.9 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 RUS75500.1 - 0.024 14.9 3.1 0.024 14.9 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Exonuc_VII_L PF02601.15 RUS75500.1 - 0.16 11.5 3.7 0.2 11.2 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GvpK PF05121.12 RUS75500.1 - 0.18 11.9 8.2 5.3 7.1 1.3 3.1 3 0 0 3 3 3 0 Gas vesicle protein K FapA PF03961.13 RUS75500.1 - 0.42 9.2 11.7 0.82 8.2 11.8 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A YlqD PF11068.8 RUS75500.1 - 0.5 10.8 14.7 0.26 11.7 9.8 2.0 1 1 1 2 2 2 0 YlqD protein Uso1_p115_C PF04871.13 RUS75500.1 - 0.78 10.1 20.1 0.4 11.1 13.5 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Endotoxin_N PF03945.14 RUS75500.1 - 1.3 8.7 8.9 3.7 7.2 3.5 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain FlxA PF14282.6 RUS75500.1 - 2.7 8.1 16.2 0.95 9.5 12.8 1.9 1 1 1 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.12 RUS75500.1 - 5.2 7.1 12.8 14 5.7 9.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 RUS75500.1 - 6.7 7.5 7.3 8.6 7.1 4.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 RUS75500.1 - 7.1 6.7 13.8 14 5.7 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2120 PF09893.9 RUS75500.1 - 8.2 6.5 9.6 1.7 8.8 3.5 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) TMPIT PF07851.13 RUS75500.1 - 9.1 5.4 13.0 24 4.1 8.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein Pyridoxal_deC PF00282.19 RUS75501.1 - 2.4e-146 487.3 0.0 2.9e-146 487.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DEFB136 PF17333.2 RUS75502.1 - 0.002 18.0 48.1 0.045 13.7 2.4 5.8 5 0 0 5 5 5 4 Beta defensin 136 Laminin_EGF PF00053.24 RUS75502.1 - 0.14 12.3 100.3 5.9 7.1 10.7 6.8 1 1 7 8 8 8 0 Laminin EGF domain Lectin_C PF00059.21 RUS75504.1 - 0.001 19.8 0.0 0.0015 19.2 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 RUS75504.1 - 0.0078 15.9 0.1 0.0085 15.8 0.1 1.1 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 RUS75505.1 - 0.0043 17.8 0.0 0.0068 17.1 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Amnionless PF14828.6 RUS75505.1 - 0.033 13.0 0.1 0.043 12.7 0.1 1.0 1 0 0 1 1 1 0 Amnionless MFS_2 PF13347.6 RUS75506.1 - 0.071 11.6 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein dCache_1 PF02743.18 RUS75507.1 - 4.3e-19 69.3 0.1 4.4e-10 39.8 0.0 3.4 3 0 0 3 3 3 2 Cache domain VWA_N PF08399.11 RUS75507.1 - 4.7e-05 23.9 0.0 0.00044 20.7 0.0 2.5 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 RUS75507.1 - 0.028 14.7 1.2 0.047 13.9 0.3 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_3 PF13768.6 RUS75507.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Fer2 PF00111.27 RUS75508.1 - 2.6e-10 40.1 0.1 4e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain UQ_con PF00179.26 RUS75509.1 - 1.4e-30 105.7 0.1 2.5e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TIL PF01826.17 RUS75510.1 - 0.096 13.0 3.2 0.16 12.2 3.2 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Phage_int_SAM_4 PF13495.6 RUS75511.1 - 0.066 13.7 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Prominin PF05478.11 RUS75511.1 - 0.24 9.3 2.0 0.34 8.8 2.0 1.2 1 0 0 1 1 1 0 Prominin ADAM_CR_2 PF17771.1 RUS75513.1 - 4.8e-12 46.2 5.3 4.8e-12 46.2 5.3 1.8 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RUS75513.1 - 2.3e-11 44.3 0.0 3.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS75513.1 - 1.7e-09 37.9 0.0 2.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS75513.1 - 2.3e-09 37.7 0.0 3.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 RUS75513.1 - 3.8e-09 36.5 0.0 5.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS75513.1 - 2.2e-06 27.7 0.1 3.4e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS75513.1 - 0.032 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Salp15 PF12115.8 RUS75513.1 - 0.097 13.1 2.3 0.29 11.6 2.3 1.7 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Somatomedin_B PF01033.17 RUS75515.1 - 8.4e-06 26.1 11.9 3.7e-05 24.0 11.9 2.2 1 0 0 1 1 1 1 Somatomedin B domain DUF4834 PF16118.5 RUS75515.1 - 0.53 11.3 2.2 1.6 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 RUS75516.1 - 0.0034 17.3 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Baculo_11_kDa PF06143.11 RUS75516.1 - 0.034 13.7 0.4 0.058 13.0 0.4 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Orf78 PF06024.12 RUS75516.1 - 0.051 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 RUS75516.1 - 0.051 14.0 0.2 0.1 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Saf_2TM PF18303.1 RUS75516.1 - 0.06 12.9 0.2 0.098 12.2 0.2 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF515 PF04415.12 RUS75516.1 - 0.078 11.4 1.7 0.088 11.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BatD PF13584.6 RUS75516.1 - 0.085 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Macoilin PF09726.9 RUS75516.1 - 0.12 10.9 0.4 0.13 10.8 0.4 1.1 1 0 0 1 1 1 0 Macoilin family EphA2_TM PF14575.6 RUS75516.1 - 0.13 13.2 0.0 0.29 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.15 RUS75516.1 - 0.21 12.2 1.0 2.7 8.6 1.0 2.0 1 1 1 2 2 2 0 Ctr copper transporter family SR-25 PF10500.9 RUS75516.1 - 0.34 10.5 22.0 0.054 13.1 15.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.18 RUS75516.1 - 0.38 9.7 3.4 0.11 11.5 0.8 1.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF755 PF05501.11 RUS75516.1 - 3.6 7.9 18.6 0.19 12.0 12.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Mito_fiss_reg PF05308.11 RUS75517.1 - 3.7 7.6 5.8 5.1 7.1 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Helo_like_N PF17111.5 RUS75518.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PyrI_C PF02748.15 RUS75519.1 - 0.013 15.4 1.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rad51 PF08423.11 RUS75520.1 - 6.2e-109 363.2 0.0 8e-109 362.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 RUS75520.1 - 1.3e-13 51.1 0.1 1.8e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 RUS75520.1 - 1.4e-07 31.1 0.1 1.5e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 RUS75520.1 - 1.3e-06 28.2 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 RUS75520.1 - 1.1e-05 25.9 0.2 2.5e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain PAXNEB PF05625.11 RUS75520.1 - 0.0062 15.7 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 1 PAXNEB protein NRD1_2 PF01995.16 RUS75520.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 Tsc35 PF15079.6 RUS75520.1 - 0.074 12.6 0.6 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 Sad1_UNC PF07738.13 RUS75521.1 - 5.3e-36 123.5 0.0 2.1e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal JIP_LZII PF16471.5 RUS75521.1 - 0.012 15.7 1.8 0.83 9.9 0.0 2.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Snapin_Pallidin PF14712.6 RUS75521.1 - 0.14 12.6 2.3 0.48 10.9 1.9 2.1 1 1 0 1 1 1 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 RUS75521.1 - 0.17 12.5 1.8 0.4 11.3 0.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ZapA PF05164.13 RUS75521.1 - 1.4 9.4 5.7 5.5 7.5 0.1 2.8 2 0 0 2 2 2 0 Cell division protein ZapA CENP-F_leu_zip PF10473.9 RUS75521.1 - 1.5 8.9 10.3 0.23 11.5 3.8 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GPO PF05929.11 RUS75521.1 - 3.7 7.1 9.0 0.21 11.1 3.3 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Complex1_LYR PF05347.15 RUS75522.1 - 1.6e-12 47.3 2.5 2.8e-12 46.5 2.5 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS75522.1 - 3.3e-06 27.8 0.4 3.7e-06 27.6 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FRG PF08867.11 RUS75522.1 - 0.11 13.4 0.5 0.17 12.9 0.2 1.5 2 0 0 2 2 2 0 FRG domain I-set PF07679.16 RUS75523.1 - 1.7e-21 76.0 0.1 1.1e-15 57.4 0.1 3.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS75523.1 - 2.6e-18 66.4 0.1 6.7e-15 55.4 0.2 4.8 5 0 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 RUS75523.1 - 8.7e-18 64.4 0.4 2.5e-12 47.0 0.5 3.0 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS75523.1 - 1.9e-11 43.9 9.8 6.1e-10 39.2 0.6 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Kazal_2 PF07648.15 RUS75523.1 - 9.3e-08 32.1 0.5 3.2e-07 30.4 0.5 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ig_6 PF18452.1 RUS75523.1 - 9.8e-06 25.0 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Kazal_1 PF00050.21 RUS75523.1 - 5.8e-05 23.0 0.5 0.00015 21.7 0.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EB PF01683.18 RUS75523.1 - 0.00019 21.7 0.9 0.00067 19.9 0.9 1.9 1 0 0 1 1 1 1 EB module V-set PF07686.17 RUS75523.1 - 0.0011 19.1 2.4 0.43 10.8 0.3 4.4 3 1 1 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS75523.1 - 0.052 13.6 0.1 0.052 13.6 0.1 2.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain UQ_con PF00179.26 RUS75524.1 - 3.8e-53 178.9 0.0 4.3e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS75524.1 - 0.00028 21.1 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 RUS75524.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 RUS75524.1 - 0.053 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.26 RUS75525.1 - 7.4e-52 174.7 0.0 8.3e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS75525.1 - 0.019 15.2 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 RUS75525.1 - 0.075 12.7 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 RUS75525.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain SNF2_N PF00176.23 RUS75526.1 - 1.4e-53 181.9 0.0 2.4e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS75526.1 - 2.9e-16 59.8 0.0 1e-15 58.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS75526.1 - 1.5e-08 34.9 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RUS75526.1 - 7e-06 25.4 0.2 3e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 RUS75526.1 - 0.01 16.2 0.1 0.055 13.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) BDHCT_assoc PF16204.5 RUS75526.1 - 0.88 9.2 6.0 0.1 12.3 1.1 1.9 2 1 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein DuoxA PF10204.9 RUS75527.1 - 1.5e-104 348.9 5.5 1.8e-104 348.7 5.5 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor Neurensin PF14927.6 RUS75527.1 - 0.25 11.1 0.0 0.25 11.1 0.0 2.2 3 0 0 3 3 3 0 Neurensin PMP22_Claudin PF00822.20 RUS75527.1 - 3 7.7 7.0 0.22 11.4 0.7 2.1 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin family WD40 PF00400.32 RUS75529.1 - 8.2e-18 64.4 8.0 7e-05 23.5 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75529.1 - 8.4e-10 38.8 0.4 0.32 11.3 0.0 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS75529.1 - 0.0087 15.9 0.0 0.4 10.5 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TGT PF01702.18 RUS75529.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Cytochrom_D1 PF02239.16 RUS75529.1 - 0.098 11.2 0.0 5.1 5.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RUS75529.1 - 0.15 11.0 0.0 5.6 5.8 0.1 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arrestin_N PF00339.29 RUS75530.1 - 2.2e-38 131.6 0.0 1.3e-34 119.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS75530.1 - 1.1e-27 97.1 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF3278 PF11683.8 RUS75531.1 - 3.2 7.8 6.1 54 3.9 3.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) CrgA PF06781.12 RUS75531.1 - 7.7 6.7 7.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 Cell division protein CrgA DUF2062 PF09835.9 RUS75531.1 - 8.5 6.2 13.7 0.15 11.9 3.1 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) zf-B_box PF00643.24 RUS75532.1 - 0.0003 20.9 2.4 0.0003 20.9 2.4 1.7 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 RUS75532.1 - 0.19 12.0 2.7 0.46 10.7 2.7 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Lys-AminoMut_A PF09043.11 RUS75534.1 - 0.083 11.3 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Jacalin PF01419.17 RUS75535.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain PARG_cat PF05028.14 RUS75536.1 - 7.4e-38 130.7 0.0 1.1e-37 130.1 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) OTU PF02338.19 RUS75536.1 - 2.8e-05 24.6 0.0 7.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Mo25 PF08569.11 RUS75537.1 - 2.3e-118 395.3 13.8 2.6e-118 395.1 13.8 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 RUS75537.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats DUF4520 PF15016.6 RUS75538.1 - 1.4e-22 79.6 0.0 1.2e-21 76.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) Elf4 PF07011.11 RUS75538.1 - 0.085 12.8 0.6 0.19 11.7 0.6 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain Hydin_ADK PF17213.3 RUS75538.1 - 1.4 9.2 7.6 0.19 12.0 2.9 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA PF00004.29 RUS75539.1 - 3.3e-16 59.9 0.0 1.1e-15 58.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RUS75539.1 - 0.0041 16.7 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 RUS75539.1 - 0.013 16.1 0.4 0.16 12.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RUS75539.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 RUS75539.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zot PF05707.12 RUS75539.1 - 0.028 14.1 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.6 RUS75539.1 - 0.029 14.8 0.2 0.19 12.1 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 RUS75539.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 RUS75539.1 - 0.03 14.3 0.1 0.21 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS75539.1 - 0.058 13.7 0.1 2.9 8.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RUS75539.1 - 0.059 13.5 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 RUS75539.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain MAPEG PF01124.18 RUS75540.1 - 4.3e-19 68.7 0.4 5.5e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Homeodomain PF00046.29 RUS75541.1 - 9.7e-23 79.8 4.8 1.7e-22 79.0 4.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS75541.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 RUS75541.1 - 0.052 13.0 0.2 0.087 12.3 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF4131 PF13567.6 RUS75542.1 - 9.4 5.9 10.3 1.7 8.2 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) E1_DerP2_DerF2 PF02221.15 RUS75543.1 - 5.2e-24 85.2 0.3 6.4e-24 84.9 0.3 1.1 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 RUS75543.1 - 0.024 15.1 0.3 0.043 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) zf-CCCH_4 PF18044.1 RUS75543.1 - 0.35 10.7 1.8 0.41 10.5 0.0 2.1 3 0 0 3 3 3 0 CCCH-type zinc finger Glyco_hydro_20 PF00728.22 RUS75545.1 - 3.8e-72 243.6 0.0 4.5e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX_C PF03174.13 RUS75545.1 - 1.8e-17 63.1 0.0 3.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Adeno_PVIII PF01310.18 RUS75546.1 - 9.8e-07 28.6 11.9 0.033 13.8 1.2 3.1 1 1 3 4 4 4 4 Adenovirus hexon associated protein, protein VIII Pox_Ag35 PF03286.14 RUS75546.1 - 0.00013 21.8 4.0 0.00017 21.4 4.0 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein PTPRCAP PF15713.5 RUS75546.1 - 0.00016 22.0 9.4 0.00024 21.4 9.4 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 RUS75546.1 - 0.0023 17.9 4.7 0.0029 17.5 4.7 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region RR_TM4-6 PF06459.12 RUS75546.1 - 0.0061 16.4 3.8 0.0081 16.0 3.8 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 RUS75546.1 - 0.0065 14.8 3.7 0.0073 14.7 3.7 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.12 RUS75546.1 - 0.028 13.8 10.6 0.036 13.4 10.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 RUS75546.1 - 0.061 13.3 6.0 0.088 12.8 6.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TFB6 PF17110.5 RUS75546.1 - 0.084 12.6 2.3 0.15 11.8 2.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop53 PF07767.11 RUS75546.1 - 0.13 11.6 13.4 0.15 11.4 13.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RPN2_C PF18004.1 RUS75546.1 - 0.41 10.5 8.2 0.56 10.1 8.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 RUS75546.1 - 0.44 9.9 2.7 0.57 9.5 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF756 PF05506.12 RUS75546.1 - 0.95 10.4 10.8 8.2 7.4 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF756) Paf1 PF03985.13 RUS75546.1 - 1 8.3 19.2 1.4 7.8 19.2 1.1 1 0 0 1 1 1 0 Paf1 PPP4R2 PF09184.11 RUS75546.1 - 1.1 8.8 14.8 1.4 8.5 14.8 1.1 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 RUS75546.1 - 1.4 8.6 10.6 2.3 7.9 10.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 RUS75546.1 - 1.4 8.3 16.5 1.8 7.9 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 RUS75546.1 - 2.2 8.5 19.4 3.1 8.0 19.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VIR_N PF15912.5 RUS75546.1 - 3.3 7.2 10.0 4.8 6.7 10.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal NOA36 PF06524.12 RUS75546.1 - 3.5 6.9 16.1 6.8 5.9 16.1 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS75546.1 - 3.8 5.5 20.7 4.8 5.1 20.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3438 PF11920.8 RUS75546.1 - 4.5 6.4 22.4 22 4.2 0.3 6.0 2 1 7 9 9 9 0 Protein of unknown function (DUF3438) Auts2 PF15336.6 RUS75546.1 - 9.3 6.3 7.2 14 5.7 7.2 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein SPRY PF00622.28 RUS75547.1 - 8.3e-19 67.9 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Nup192 PF11894.8 RUS75549.1 - 0.0014 15.8 0.7 0.0015 15.8 0.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Orexin PF02072.15 RUS75549.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Prepro-orexin Nup188 PF10487.9 RUS75550.1 - 1.5e-69 235.0 0.0 1.7e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup192 PF11894.8 RUS75550.1 - 1e-06 26.3 0.0 2.1e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 RUS75552.1 - 4.4e-66 223.5 0.2 5e-66 223.3 0.2 1.0 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Peptidase_M15_4 PF13539.6 RUS75552.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase VWA PF00092.28 RUS75554.1 - 3.5e-47 160.9 1.6 3.4e-39 134.9 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS75554.1 - 3.2e-14 53.5 0.0 5.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 RUS75554.1 - 1.3e-12 47.7 11.5 2.3e-12 46.9 11.5 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain VWA_3 PF13768.6 RUS75554.1 - 5.4e-05 23.2 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 RUS75554.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus HTH_psq PF05225.16 RUS75554.1 - 0.048 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DHHC PF01529.20 RUS75555.1 - 1.7e-36 125.2 11.8 2.5e-36 124.7 9.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase WD40 PF00400.32 RUS75556.1 - 8.6e-62 203.6 18.3 5.4e-10 39.7 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75556.1 - 2.9e-25 88.4 1.2 0.00055 20.2 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS75556.1 - 6.1e-15 55.6 0.8 3.5e-07 30.3 0.0 3.5 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RUS75556.1 - 1.2e-13 50.6 3.1 0.004 15.9 0.0 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS75556.1 - 7.2e-07 28.8 0.1 0.014 14.7 0.0 3.2 1 1 3 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 RUS75556.1 - 1.8e-05 23.9 4.6 0.16 10.9 0.7 4.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 RUS75556.1 - 0.0001 21.4 1.1 2.2 7.1 0.0 4.1 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RUS75556.1 - 0.00013 20.5 0.0 0.019 13.3 0.0 2.8 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 RUS75556.1 - 0.012 15.4 1.1 13 5.5 0.1 3.9 3 1 1 4 4 4 0 TUP1-like enhancer of split VID27 PF08553.10 RUS75556.1 - 0.013 14.5 0.0 0.26 10.3 0.0 2.4 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 RUS75556.1 - 0.014 13.9 0.0 0.71 8.3 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Bromodomain PF00439.25 RUS75557.1 - 1.4e-44 150.1 2.6 1.7e-21 76.1 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 RUS75557.1 - 3.3e-29 100.9 0.3 1.1e-28 99.2 0.3 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 RUS75557.1 - 8.6e-06 25.3 11.2 8.6e-06 25.3 11.2 2.5 2 1 0 2 2 2 1 C-terminal domain of bromodomain protein 4 EAP30 PF04157.16 RUS75557.1 - 0.00079 18.8 1.3 0.00079 18.8 1.3 1.9 2 0 0 2 2 2 1 EAP30/Vps36 family AATF-Che1 PF13339.6 RUS75557.1 - 0.017 15.8 3.2 0.017 15.8 3.2 4.5 4 1 0 4 4 4 0 Apoptosis antagonizing transcription factor Myb_DNA-binding PF00249.31 RUS75558.1 - 6.6e-38 128.7 0.8 5.6e-12 45.6 0.0 4.7 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS75558.1 - 4.8e-32 110.0 6.6 5.2e-09 36.2 0.0 4.9 3 1 1 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 RUS75558.1 - 0.23 11.5 4.7 0.53 10.3 0.0 3.5 2 1 1 3 3 3 0 SLIDE Chorion_2 PF03964.15 RUS75558.1 - 0.39 11.6 10.8 0.27 12.1 1.7 3.2 2 0 0 2 2 2 0 Chorion family 2 DUF1640 PF07798.11 RUS75559.1 - 2.9 7.9 13.0 1.5 8.9 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1640) Ig_3 PF13927.6 RUS75560.1 - 2.3e-05 24.9 0.1 1.5 9.5 0.0 4.0 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS75560.1 - 0.0001 22.3 0.0 0.36 10.9 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 RUS75560.1 - 0.00017 21.7 0.0 0.34 11.1 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS75560.1 - 0.00039 20.7 0.1 0.073 13.4 0.0 3.3 4 0 0 4 4 4 1 Immunoglobulin domain LYRIC PF15686.5 RUS75560.1 - 0.0021 17.7 0.1 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family ig PF00047.25 RUS75560.1 - 0.0026 17.9 0.0 14 6.0 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain TMEM154 PF15102.6 RUS75560.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family G6B PF15096.6 RUS75560.1 - 0.16 11.8 0.2 10 5.8 0.0 3.0 3 0 0 3 3 3 0 G6B family TMEM52 PF14979.6 RUS75560.1 - 0.16 11.9 0.7 0.37 10.7 0.7 1.6 1 0 0 1 1 1 0 Transmembrane 52 Izumo-Ig PF16706.5 RUS75560.1 - 0.17 12.0 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Prominin PF05478.11 RUS75560.1 - 0.45 8.4 2.3 0.64 7.9 2.3 1.1 1 0 0 1 1 1 0 Prominin V-set PF07686.17 RUS75563.1 - 1.1e-05 25.6 0.3 0.095 12.9 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin V-set domain Ig_3 PF13927.6 RUS75563.1 - 1.3e-05 25.7 2.2 0.014 15.9 0.0 4.3 4 1 0 4 4 4 1 Immunoglobulin domain ig PF00047.25 RUS75563.1 - 1.8e-05 24.8 0.8 2.8 8.2 0.0 4.8 4 1 1 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 RUS75563.1 - 0.00062 20.1 0.3 0.49 10.8 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 RUS75563.1 - 0.0016 18.5 0.0 0.38 10.9 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin I-set domain PhyH PF05721.13 RUS75564.1 - 2.5e-60 204.4 0.0 2.9e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Trp_repressor PF01371.19 RUS75564.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein ubiquitin PF00240.23 RUS75565.1 - 4e-19 68.2 0.5 6.6e-19 67.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family BAG6 PF12057.8 RUS75565.1 - 6.7e-19 67.7 1.2 1.8e-18 66.3 1.2 1.8 1 0 0 1 1 1 1 BCL2-associated athanogene 6 Rad60-SLD PF11976.8 RUS75565.1 - 1.3e-07 31.3 0.6 1e-06 28.5 1.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS75565.1 - 0.052 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RUS75565.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4701 PF15773.5 RUS75566.1 - 0.094 11.7 0.7 0.13 11.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) Cupin_8 PF13621.6 RUS75567.1 - 9.6e-41 140.2 0.0 1.3e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RUS75567.1 - 5.5e-07 29.4 0.1 1.2e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 RUS75567.1 - 0.066 13.6 0.2 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF4220 PF13968.6 RUS75568.1 - 0.08 12.3 4.6 0.085 12.2 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) C_tripleX PF02363.19 RUS75568.1 - 0.38 11.1 3.0 0.47 10.8 0.5 2.2 2 0 0 2 2 2 0 Cysteine rich repeat Ctr PF04145.15 RUS75569.1 - 2.7e-35 122.1 3.4 4.8e-35 121.4 3.4 1.4 1 0 0 1 1 1 1 Ctr copper transporter family mRNA_decap_C PF16741.5 RUS75569.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Band_7 PF01145.25 RUS75570.1 - 1.4e-16 61.0 0.0 1.8e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family HalX PF08663.10 RUS75571.1 - 0.0069 16.7 5.4 0.0069 16.7 5.4 4.4 4 2 3 7 7 7 1 HalX domain Cep57_CLD_2 PF14197.6 RUS75571.1 - 0.16 12.1 28.1 1 9.5 9.6 4.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4515 PF14988.6 RUS75571.1 - 0.27 11.0 49.4 0.045 13.6 32.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) HK97-gp10_like PF04883.12 RUS75571.1 - 0.81 10.7 0.1 0.81 10.7 0.1 3.2 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component ATG16 PF08614.11 RUS75571.1 - 2.2 8.5 48.4 0.58 10.3 10.7 4.0 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) UPA_2 PF17809.1 RUS75573.1 - 1.6e-52 176.8 0.1 6.4e-52 174.8 0.1 2.2 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 RUS75573.1 - 1.9e-30 105.1 1.1 9.9e-24 83.5 0.0 3.0 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 RUS75573.1 - 1.4e-15 57.2 0.2 3.8e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Death domain Clr2 PF10383.9 RUS75575.1 - 4.4 8.1 5.2 1.7 9.4 1.2 2.5 2 1 0 2 2 2 0 Transcription-silencing protein Clr2 Glycos_transf_2 PF00535.26 RUS75577.1 - 1.2e-23 83.8 0.0 2.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS75577.1 - 1.7e-08 34.6 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RUS75577.1 - 6.5e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 RUS75577.1 - 3e-06 27.6 0.0 0.0002 21.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 RUS75577.1 - 0.0023 17.9 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Lin-8 PF03353.15 RUS75578.1 - 0.46 10.0 5.4 0.69 9.4 5.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cadherin PF00028.17 RUS75579.1 - 2.5e-79 261.8 4.7 7.9e-23 80.7 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 RUS75579.1 - 3.1e-14 52.6 0.1 2.1e-08 33.9 0.0 5.1 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 RUS75579.1 - 2.7e-07 30.5 1.7 0.98 9.4 0.0 5.0 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 RUS75579.1 - 0.00041 20.6 0.0 0.84 9.9 0.0 3.9 4 0 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 RUS75579.1 - 0.0013 19.3 35.0 0.0032 18.1 0.1 6.0 5 1 0 5 5 5 3 Bacterial cadherin-like domain Y_Y_Y PF07495.13 RUS75579.1 - 0.0021 18.0 0.4 4.6 7.3 0.3 4.4 5 0 0 5 5 5 1 Y_Y_Y domain He_PIG PF05345.12 RUS75579.1 - 0.046 13.9 6.3 11 6.3 0.3 6.2 6 1 0 6 6 6 0 Putative Ig domain 7tm_1 PF00001.21 RUS75580.1 - 4.9e-24 85.1 0.3 6.4e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS75580.1 - 3.2e-06 27.0 2.8 5.7e-06 26.1 2.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS75580.1 - 0.0032 16.9 5.8 0.013 14.9 5.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS75580.1 - 0.013 15.3 0.2 0.013 15.3 0.2 1.9 2 0 0 2 2 2 0 Olfactory receptor Vps53_N PF04100.12 RUS75581.1 - 4.4e-158 526.2 3.2 6.2e-158 525.7 1.0 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 RUS75581.1 - 1.8e-09 37.3 1.1 3.8e-09 36.2 1.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 RUS75581.1 - 5.3e-06 26.5 0.6 0.0001 22.2 0.0 2.7 3 0 0 3 3 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 RUS75581.1 - 5.4e-05 22.2 3.0 5.4e-05 22.2 3.0 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein Sec8_exocyst PF04048.14 RUS75581.1 - 0.0031 17.4 1.4 0.0067 16.3 0.4 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 RUS75581.1 - 0.0031 17.5 1.7 0.0031 17.5 1.7 2.2 3 0 0 3 3 2 1 Laminin Domain II LXG PF04740.12 RUS75581.1 - 0.0048 16.6 1.3 0.018 14.8 0.2 2.3 2 0 0 2 2 2 1 LXG domain of WXG superfamily GrpE PF01025.19 RUS75581.1 - 0.0058 16.3 6.0 0.015 15.0 4.3 2.3 2 0 0 2 2 2 1 GrpE NBD94 PF16830.5 RUS75581.1 - 0.0063 16.9 4.1 0.017 15.5 4.1 1.7 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH AAA_13 PF13166.6 RUS75581.1 - 0.012 14.2 0.3 0.029 13.0 0.3 1.5 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.11 RUS75581.1 - 0.013 15.6 0.7 0.81 9.8 0.0 3.4 2 1 1 3 3 3 0 Vps51/Vps67 COG5 PF10392.9 RUS75581.1 - 0.019 15.1 1.1 0.058 13.6 0.0 2.4 3 0 0 3 3 2 0 Golgi transport complex subunit 5 Sec34 PF04136.15 RUS75581.1 - 0.025 14.4 1.3 0.11 12.4 1.3 2.1 1 0 0 1 1 1 0 Sec34-like family DUF1664 PF07889.12 RUS75581.1 - 0.071 13.2 9.4 0.21 11.6 3.8 4.0 3 2 2 5 5 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 RUS75581.1 - 0.11 12.7 4.5 0.2 11.9 1.9 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2570 PF10828.8 RUS75581.1 - 0.13 12.1 1.1 0.44 10.4 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4337 PF14235.6 RUS75581.1 - 0.19 11.8 1.0 0.4 10.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2009 PF09418.10 RUS75581.1 - 0.23 10.5 0.0 0.23 10.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2009) TMPIT PF07851.13 RUS75581.1 - 0.24 10.6 1.0 0.48 9.6 1.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 RUS75581.1 - 0.28 11.7 4.8 7.8 7.0 0.6 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 RUS75581.1 - 0.3 10.9 2.7 0.28 11.0 0.9 1.9 2 0 0 2 2 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lipoprotein_7 PF01540.16 RUS75581.1 - 0.38 10.0 5.2 9.5 5.4 2.8 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein XhlA PF10779.9 RUS75581.1 - 0.39 10.9 8.7 0.059 13.6 3.4 2.4 3 0 0 3 3 1 0 Haemolysin XhlA Tropomyosin PF00261.20 RUS75581.1 - 0.64 9.3 9.8 0.047 13.1 1.5 2.5 3 0 0 3 3 3 0 Tropomyosin ING PF12998.7 RUS75581.1 - 0.81 10.3 6.9 0.59 10.7 3.8 2.5 2 0 0 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.9 RUS75581.1 - 1.4 9.2 7.6 1.8 8.9 2.9 3.2 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cauli_AT PF03233.13 RUS75581.1 - 1.8 8.5 5.5 3.3 7.6 3.2 2.6 1 1 1 2 2 2 0 Aphid transmission protein Tropomyosin_1 PF12718.7 RUS75581.1 - 1.9 8.6 9.0 0.31 11.2 2.1 2.9 3 0 0 3 3 3 0 Tropomyosin like HAP1_N PF04849.13 RUS75581.1 - 2.1 7.5 9.8 0.84 8.8 1.6 2.7 3 0 0 3 3 3 0 HAP1 N-terminal conserved region COG2 PF06148.11 RUS75581.1 - 3.6 7.7 9.6 0.59 10.2 2.2 3.4 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.6 RUS75581.1 - 4.1 7.8 8.7 3.4 8.1 4.1 3.4 2 1 0 2 2 1 0 Syntaxin-like protein Metallophos PF00149.28 RUS75582.1 - 5.7e-12 46.6 0.0 7.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS75582.1 - 0.00028 21.1 0.0 0.00044 20.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SUIM_assoc PF16619.5 RUS75583.1 - 0.0038 17.3 0.0 0.0038 17.3 0.0 4.5 4 1 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 DUF1387 PF07139.11 RUS75583.1 - 0.25 11.0 9.8 0.53 10.0 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CPSF100_C PF13299.6 RUS75583.1 - 0.57 10.3 5.9 1.5 9.0 5.9 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4407 PF14362.6 RUS75583.1 - 2.2 7.6 4.2 21 4.4 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 RUS75583.1 - 3.4 7.1 18.2 0.32 10.5 13.3 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FAM76 PF16046.5 RUS75583.1 - 3.5 6.9 17.5 17 4.7 17.8 1.9 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 RUS75583.1 - 3.9 5.9 12.7 6.3 5.2 12.7 1.2 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 RUS75583.1 - 6.7 5.6 12.1 11 4.9 12.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PNISR PF15996.5 RUS75583.1 - 8.6 6.6 17.3 24 5.1 17.3 1.7 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Glyco_hydro_63 PF03200.16 RUS75585.1 - 8.4e-12 44.6 11.3 2.5e-07 29.9 1.1 5.0 5 1 0 5 5 5 4 Glycosyl hydrolase family 63 C-terminal domain GIT1_C PF12205.8 RUS75588.1 - 2.6e-38 130.7 0.3 6.7e-38 129.4 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term ArfGap PF01412.18 RUS75588.1 - 2.4e-28 98.6 0.6 5.7e-28 97.3 0.6 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 RUS75588.1 - 8.2e-26 89.3 3.3 4.1e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_5 PF13857.6 RUS75588.1 - 1.3e-09 38.1 0.0 6.1e-09 36.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75588.1 - 1.8e-08 34.9 0.0 4.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75588.1 - 1e-07 32.4 0.0 6.1e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GIT_CC PF16559.5 RUS75588.1 - 6.1e-07 29.2 0.2 2.1e-06 27.5 0.2 1.9 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Ank PF00023.30 RUS75588.1 - 0.00045 20.6 0.0 0.038 14.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 RUS75588.1 - 0.003 17.9 0.0 1.9 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat DUF4854 PF16146.5 RUS75588.1 - 0.11 12.9 1.1 12 6.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) TTRAP PF14203.6 RUS75588.1 - 0.16 12.0 0.0 0.75 9.8 0.1 2.1 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein MMR_HSR1_Xtn PF16897.5 RUS75589.1 - 1.6e-42 143.9 1.0 3.1e-42 142.9 1.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 RUS75589.1 - 5.8e-25 87.1 0.0 1.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 RUS75589.1 - 4.7e-19 68.6 0.0 1.1e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS75589.1 - 2.3e-10 40.2 0.2 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 RUS75589.1 - 0.0089 15.0 0.2 0.023 13.7 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 RUS75589.1 - 0.0093 15.5 0.0 3.7 7.0 0.0 3.5 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RUS75589.1 - 0.012 15.7 0.3 2.7 8.0 0.2 2.5 1 1 1 2 2 2 0 Dynamin family adh_short PF00106.25 RUS75590.1 - 4.7e-26 91.5 0.0 2.6e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS75590.1 - 3e-15 56.4 0.0 5.8e-15 55.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS75590.1 - 5e-08 33.1 0.1 7.4e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS75590.1 - 2.4e-07 30.4 0.1 3.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RUS75590.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS75590.1 - 0.0015 17.7 0.1 0.0027 16.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 RUS75590.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Baculo_11_kDa PF06143.11 RUS75590.1 - 0.02 14.4 0.4 0.045 13.3 0.4 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family THF_DHG_CYH_C PF02882.19 RUS75590.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.8 RUS75590.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain Shikimate_DH PF01488.20 RUS75590.1 - 4.6 7.3 6.1 1.4 9.0 1.3 2.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 RUS75591.1 - 9.8e-31 106.9 33.1 1.8e-19 69.9 16.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS75591.1 - 2.9e-30 105.5 27.4 1.3e-24 86.9 7.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 RUS75591.1 - 0.0019 16.9 3.1 0.0019 16.9 3.1 3.2 4 1 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 RUS75591.1 - 0.12 11.2 0.1 0.12 11.2 0.1 3.1 2 1 1 3 3 3 0 MFS_1 like family Fructosamin_kin PF03881.14 RUS75592.1 - 9.7e-67 225.2 0.9 3.1e-66 223.5 0.9 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 RUS75592.1 - 4e-13 49.8 0.0 5.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RUS75592.1 - 0.0013 18.1 0.3 0.0018 17.6 0.3 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 RUS75592.1 - 0.085 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PMP22_Claudin PF00822.20 RUS75593.1 - 3.3e-09 36.8 8.0 4.5e-09 36.4 8.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 RUS75593.1 - 0.00012 22.4 15.1 0.00069 19.9 15.1 1.9 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein EI24 PF07264.11 RUS75593.1 - 0.0012 19.1 1.5 0.01 16.1 0.1 2.0 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF973 PF06157.11 RUS75593.1 - 0.0014 17.7 1.1 0.0022 17.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Colicin_V PF02674.16 RUS75593.1 - 0.0024 17.8 5.5 0.0024 17.8 5.5 2.0 2 1 0 2 2 2 1 Colicin V production protein Amastin PF07344.11 RUS75593.1 - 0.0045 16.8 12.8 0.0045 16.8 12.8 2.0 1 1 0 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.6 RUS75593.1 - 0.0052 16.6 15.9 0.16 11.7 15.9 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4199 PF13858.6 RUS75593.1 - 0.018 15.5 4.0 0.018 15.5 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF805 PF05656.14 RUS75593.1 - 0.019 15.4 3.8 0.019 15.4 3.8 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF805) DUF4293 PF14126.6 RUS75593.1 - 0.041 14.1 5.0 0.057 13.7 3.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2070 PF09843.9 RUS75593.1 - 0.05 11.9 0.9 0.052 11.8 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Claudin_3 PF06653.11 RUS75593.1 - 0.066 13.1 13.1 0.3 11.0 11.3 2.3 2 1 0 2 2 2 0 Tight junction protein, Claudin-like DUF4834 PF16118.5 RUS75593.1 - 0.19 12.7 0.0 0.19 12.7 0.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Clc-like PF07062.12 RUS75593.1 - 0.27 10.7 14.0 0.12 11.8 11.5 1.6 1 1 1 2 2 2 0 Clc-like Abhydrolase_9_N PF15420.6 RUS75593.1 - 0.41 10.6 3.5 0.18 11.8 0.8 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus TssN PF17555.2 RUS75593.1 - 0.64 9.3 4.1 1 8.7 4.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN PhoLip_ATPase_C PF16212.5 RUS75593.1 - 2.1 8.0 9.2 1 9.0 7.2 1.6 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal DUF4006 PF13179.6 RUS75593.1 - 2.5 8.1 6.8 6.3 6.8 0.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF4006) DUF4231 PF14015.6 RUS75593.1 - 2.8 8.5 4.8 4.3 7.8 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.8 RUS75593.1 - 8.7 6.2 15.9 0.04 13.8 4.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Collagen PF01391.18 RUS75594.1 - 0.33 10.8 18.1 0.69 9.7 18.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PDEase_I PF00233.19 RUS75595.1 - 6.5e-85 284.6 2.8 6.5e-85 284.6 2.8 2.2 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 RUS75595.1 - 9.8e-31 105.4 0.1 2.8e-30 103.9 0.1 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal CENP-B_dimeris PF09026.10 RUS75595.1 - 4.5 7.7 11.8 0.19 12.2 4.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GYF_2 PF14237.6 RUS75597.1 - 4e-20 71.4 0.4 1.1e-19 69.9 0.4 1.9 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 RUS75597.1 - 1.7e-14 53.7 1.9 3e-14 52.9 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.23 RUS75597.1 - 0.021 14.9 1.1 1.6 8.9 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat VapB_antitoxin PF09957.9 RUS75597.1 - 1.4 8.9 3.9 0.66 9.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Ldh_1_N PF00056.23 RUS75599.1 - 4.1e-08 33.4 0.0 6.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Nop14 PF04147.12 RUS75599.1 - 1.3e-05 23.6 31.7 1.5e-05 23.5 31.7 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS75599.1 - 2.5e-05 22.8 26.6 3.2e-05 22.5 26.6 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS75599.1 - 0.0001 21.9 33.8 0.00012 21.7 33.8 1.1 1 0 0 1 1 1 1 SDA1 Ldh_1_C PF02866.18 RUS75599.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Mpp10 PF04006.12 RUS75599.1 - 0.0052 15.3 25.4 0.0063 15.0 25.4 1.1 1 0 0 1 1 1 1 Mpp10 protein SAPS PF04499.15 RUS75599.1 - 0.33 9.7 11.9 0.34 9.7 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FRQ PF09421.10 RUS75599.1 - 0.49 8.4 16.8 0.47 8.4 16.8 1.1 1 0 0 1 1 1 0 Frequency clock protein Drc1-Sld2 PF11719.8 RUS75599.1 - 0.86 9.1 15.2 1.1 8.7 15.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein BUD22 PF09073.10 RUS75599.1 - 3.2 7.0 39.2 4 6.7 39.2 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 RUS75599.1 - 4.2 6.4 31.5 5.3 6.1 31.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF913 PF06025.12 RUS75599.1 - 6.8 5.6 12.9 15 4.4 12.9 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) CLTH PF10607.9 RUS75600.1 - 9.2e-32 110.0 1.0 1.2e-31 109.6 1.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RUS75600.1 - 1e-08 34.8 0.1 2.2e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 LisH TINF2_N PF14973.6 RUS75600.1 - 0.035 14.5 0.2 0.085 13.2 0.2 1.7 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus CLTH PF10607.9 RUS75601.1 - 5.9e-21 74.9 0.8 7.5e-21 74.6 0.8 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RUS75601.1 - 6.1e-09 35.5 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 LisH TINF2_N PF14973.6 RUS75601.1 - 0.021 15.2 0.6 0.033 14.5 0.3 1.5 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Ribosomal_L27A PF00828.19 RUS75601.1 - 0.18 12.5 0.0 0.24 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5565 PF17720.1 RUS75602.1 - 9e-122 406.0 1.4 3.3e-100 335.1 0.4 2.0 2 0 0 2 2 2 2 Family of unknown function (DUF5565) Bunya_NS-S PF01104.17 RUS75602.1 - 0.19 11.6 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s CENP-B_dimeris PF09026.10 RUS75602.1 - 7.7 7.0 11.7 15 6.0 11.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GFO_IDH_MocA PF01408.22 RUS75603.1 - 6e-07 30.3 0.0 9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 RUS75603.1 - 0.003 18.1 0.0 0.0067 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 RUS75603.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 7tm_1 PF00001.21 RUS75604.1 - 7.6e-21 74.6 27.3 1.5e-20 73.7 27.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2721 PF11026.8 RUS75604.1 - 0.028 14.3 1.5 0.028 14.3 1.5 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2721) 7tm_1 PF00001.21 RUS75607.1 - 0.77 9.0 8.0 1 8.7 8.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GST_C_3 PF14497.6 RUS75609.1 - 2.6e-17 62.8 0.1 4.4e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS75609.1 - 3.1e-09 37.1 0.0 7.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS75609.1 - 1.4e-07 31.7 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS75609.1 - 2e-07 31.3 0.0 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RUS75609.1 - 0.0067 17.1 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 RUS75609.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_4 PF13637.6 RUS75610.1 - 4.7e-09 36.6 0.3 3e-06 27.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75610.1 - 2.2e-06 28.2 0.0 5.7e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS75610.1 - 2.9e-05 24.3 0.3 0.04 14.4 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RUS75610.1 - 4e-05 23.7 0.1 0.094 13.3 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS75610.1 - 0.00011 22.4 2.9 0.028 14.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75612.1 - 1.1e-17 64.3 0.2 5.8e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75612.1 - 6.7e-12 45.7 1.9 0.011 16.4 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75612.1 - 4.5e-10 38.9 0.7 0.0045 17.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RUS75612.1 - 2.4e-09 37.3 0.9 0.19 12.1 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS75612.1 - 2.9e-07 30.6 4.2 0.33 11.5 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ammonium_transp PF00909.21 RUS75613.1 - 5.7e-51 173.4 11.8 6.5e-51 173.3 11.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HSBP1 PF06825.12 RUS75613.1 - 0.28 11.1 0.3 0.4 10.6 0.3 1.2 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Ammonium_transp PF00909.21 RUS75614.1 - 1.4e-107 359.8 27.8 1.7e-107 359.6 27.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UCH PF00443.29 RUS75615.1 - 1.4e-40 139.4 0.0 2.2e-40 138.8 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 RUS75615.1 - 3.6e-27 94.2 0.0 6.9e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain USP7_C2 PF14533.6 RUS75615.1 - 8.1e-12 45.3 0.2 4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal DUSP PF06337.12 RUS75615.1 - 1.1e-11 45.2 1.1 3e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 RUS75615.1 - 2.7e-06 27.2 0.0 0.00015 21.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 RUS75615.1 - 0.0016 17.8 0.1 0.0051 16.1 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ribosomal_S27e PF01667.17 RUS75615.1 - 0.15 11.8 0.2 0.37 10.5 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 UCH PF00443.29 RUS75616.1 - 1.6e-34 119.6 1.0 2e-34 119.3 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS75616.1 - 4.7e-09 36.3 0.1 6.4e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.20 RUS75616.1 - 0.86 10.1 4.1 1.9 9.0 4.1 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat PI-PLC-X PF00388.19 RUS75617.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Varsurf_PPLC PF03490.13 RUS75617.1 - 0.12 12.3 0.1 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Glyco_hydro_35 PF01301.19 RUS75617.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 RVT_1 PF00078.27 RUS75618.1 - 4.6e-23 81.9 0.0 8.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS75618.1 - 1.7e-20 73.4 0.0 3.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS75618.1 - 1.4e-16 60.3 0.0 1.4e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain SCAN PF02023.17 RUS75618.1 - 1.5e-11 44.0 0.0 4.3e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 SCAN domain rve_3 PF13683.6 RUS75618.1 - 7.7e-05 22.4 0.0 0.00025 20.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 RUS75618.1 - 9.3e-05 22.3 3.8 9.3e-05 22.3 3.8 2.8 2 0 0 2 2 2 1 Zinc knuckle ABC_tran_CTD PF16326.5 RUS75618.1 - 0.055 13.7 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain zf-CCHC_4 PF14392.6 RUS75618.1 - 0.14 11.9 4.6 4.7 7.0 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RUS75618.1 - 5.6 6.9 9.5 6.9 6.6 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 RUS75619.1 - 2.3e-23 82.9 0.0 3.8e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS75619.1 - 4.1e-13 49.6 0.0 8.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS75619.1 - 4.4e-05 23.2 0.0 0.00014 21.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Alg6_Alg8 PF03155.15 RUS75620.1 - 1.7e-67 228.4 10.4 2e-67 228.2 10.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VIT1 PF01988.19 RUS75620.1 - 2.2 8.1 5.9 7.3 6.4 1.4 2.3 2 0 0 2 2 2 0 VIT family Ost5 PF05251.12 RUS75620.1 - 3.2 8.1 8.3 0.15 12.3 1.4 2.4 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Alg6_Alg8 PF03155.15 RUS75621.1 - 5.3e-135 451.1 32.5 1.1e-92 311.5 18.0 2.4 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ost5 PF05251.12 RUS75621.1 - 1.8 8.9 7.1 0.27 11.5 1.4 2.7 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 LRR_9 PF14580.6 RUS75622.1 - 5.1e-12 45.6 0.3 1.6e-11 44.0 0.4 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 RUS75622.1 - 6.4e-09 36.0 9.3 1.8e-05 25.0 0.6 3.7 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS75622.1 - 1.5e-07 31.1 7.1 7.6e-05 22.4 1.7 3.4 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 RUS75622.1 - 0.68 10.7 9.6 26 5.9 0.1 4.7 3 2 0 3 3 3 0 Leucine Rich Repeat zf-RING_2 PF13639.6 RUS75623.1 - 2.2e-07 31.1 6.1 4.2e-07 30.2 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RUS75623.1 - 9e-06 25.9 6.0 1.6e-05 25.1 6.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS75623.1 - 0.00011 22.0 4.5 0.00025 20.9 4.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS75623.1 - 0.0012 18.8 2.3 0.0089 16.0 2.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS75623.1 - 0.0043 17.0 6.4 0.0077 16.2 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 RUS75623.1 - 0.0068 16.1 3.4 0.023 14.4 3.4 2.0 1 1 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 RUS75623.1 - 0.0083 16.2 3.5 0.017 15.2 3.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 RUS75623.1 - 0.0086 15.9 8.6 0.04 13.8 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS75623.1 - 0.032 14.1 4.9 0.056 13.3 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 RUS75623.1 - 0.04 13.9 0.9 0.13 12.3 0.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 RUS75623.1 - 0.074 13.2 2.7 0.19 11.9 2.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RUS75623.1 - 0.12 12.5 6.6 2.3 8.5 6.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 RUS75623.1 - 0.13 12.1 5.7 0.35 10.8 5.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RUS75623.1 - 0.28 10.9 7.4 0.86 9.3 7.4 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF5411 PF17424.2 RUS75623.1 - 0.56 10.2 2.4 20 5.2 0.8 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5411) zf-UDP PF14569.6 RUS75623.1 - 0.79 9.9 4.6 2 8.6 4.6 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger DUF92 PF01940.16 RUS75623.1 - 4 6.8 6.5 15 4.9 6.5 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF92 Rtf2 PF04641.12 RUS75623.1 - 5.3 6.3 4.4 12 5.2 4.7 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger PDGF PF00341.17 RUS75624.1 - 2.4e-14 53.4 5.9 2.4e-14 53.4 5.9 3.2 3 1 0 3 3 3 1 PDGF/VEGF domain DUF3439 PF11921.8 RUS75624.1 - 0.0072 16.3 6.9 0.014 15.3 6.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 RUS75624.1 - 0.057 11.4 2.8 0.076 11.0 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 RUS75624.1 - 0.25 11.3 21.6 0.033 14.2 16.6 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein SOG2 PF10428.9 RUS75624.1 - 0.95 8.6 5.5 1.4 8.0 5.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CXCXC PF03128.14 RUS75624.1 - 8.4 7.1 36.2 1.3 9.6 1.9 5.8 5 0 0 5 5 5 0 CXCXC repeat PDGF PF00341.17 RUS75625.1 - 6.9e-13 48.7 3.3 6.9e-13 48.7 3.3 2.5 2 0 0 2 2 2 1 PDGF/VEGF domain Cyclin_N PF00134.23 RUS75626.1 - 6.4e-07 29.2 0.1 0.025 14.3 0.1 2.5 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS75626.1 - 0.04 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Cyclin, C-terminal domain OATP PF03137.20 RUS75627.1 - 0.076 11.3 4.9 0.089 11.1 4.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YL1 PF05764.13 RUS75627.1 - 0.12 12.4 25.9 0.18 11.9 25.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpb1_5 PF04998.17 RUS75627.1 - 0.19 11.2 5.8 0.26 10.7 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FHIPEP PF00771.20 RUS75627.1 - 0.49 8.8 6.6 0.56 8.6 6.6 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4770 PF15994.5 RUS75627.1 - 0.62 10.3 15.6 0.98 9.6 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Otopetrin PF03189.13 RUS75627.1 - 0.78 8.5 1.7 0.83 8.4 1.7 1.2 1 0 0 1 1 1 0 Otopetrin Vfa1 PF08432.10 RUS75627.1 - 0.93 9.8 27.2 1.5 9.1 27.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PIEZO PF15917.5 RUS75627.1 - 1.1 8.7 15.1 1.6 8.2 15.1 1.2 1 0 0 1 1 1 0 Piezo Peptidase_U57 PF05582.12 RUS75627.1 - 2.7 7.2 12.3 3.6 6.8 12.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 EIIBC-GUT_N PF03612.14 RUS75627.1 - 2.7 7.7 11.6 4.8 6.9 11.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NPR3 PF03666.13 RUS75627.1 - 3.6 6.3 19.0 4.3 6.0 19.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RUS75627.1 - 4.1 6.1 10.3 5 5.8 10.3 1.1 1 0 0 1 1 1 0 Presenilin ICA69 PF04629.14 RUS75627.1 - 4.4 7.6 12.7 6.3 7.0 12.7 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain MDM10 PF12519.8 RUS75627.1 - 5.1 5.8 10.0 6 5.6 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 RUS75627.1 - 8.2 5.1 10.4 10 4.8 10.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 RUS75627.1 - 8.4 5.5 7.5 11 5.2 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cyclin_N PF00134.23 RUS75628.1 - 7.3e-24 83.9 0.9 2e-23 82.5 0.9 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS75628.1 - 0.00015 21.9 0.2 0.00062 19.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cnd1 PF12717.7 RUS75630.1 - 6.9e-06 26.2 16.7 0.033 14.2 1.3 6.8 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RUS75630.1 - 0.00043 20.5 0.2 0.23 11.7 0.0 3.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Peptidase_M85 PF13678.6 RUS75630.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease TAFH PF07531.14 RUS75630.1 - 0.052 13.6 0.7 23 5.2 0.1 3.8 3 0 0 3 3 3 0 NHR1 homology to TAF IFRD PF05004.13 RUS75630.1 - 0.066 12.3 0.4 3.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) V-ATPase_H_N PF03224.14 RUS75630.1 - 0.088 12.1 3.2 0.31 10.3 0.1 3.0 2 1 0 2 2 2 0 V-ATPase subunit H FANCI_S2 PF14676.6 RUS75630.1 - 0.37 11.1 5.1 3.5 7.9 0.1 3.5 3 1 0 3 3 3 0 FANCI solenoid 2 Sen15 PF09631.10 RUS75631.1 - 5.8e-20 71.5 0.0 8.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein zf-H2C2_2 PF13465.6 RUS75632.1 - 1.6e-29 100.9 92.3 8.2e-08 32.3 1.6 12.5 13 0 0 13 13 13 9 Zinc-finger double domain zf-C2H2 PF00096.26 RUS75632.1 - 1.6e-17 62.9 100.6 0.00084 19.7 1.1 11.4 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS75632.1 - 6.4e-13 48.2 75.6 2.7e-06 27.0 1.5 8.9 9 0 0 9 9 9 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS75632.1 - 1e-11 44.6 96.6 0.0072 17.1 2.2 11.3 11 0 0 11 11 11 8 C2H2-type zinc finger zf-Dof PF02701.15 RUS75632.1 - 0.0016 18.5 0.6 0.0016 18.5 0.6 4.5 4 1 2 6 6 6 1 Dof domain, zinc finger GAGA PF09237.11 RUS75632.1 - 0.003 17.3 6.2 0.018 14.8 0.1 3.9 3 1 1 4 4 4 1 GAGA factor zf-C2H2_jaz PF12171.8 RUS75632.1 - 0.028 14.7 3.8 0.028 14.7 3.8 9.2 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding DUF4474 PF14751.6 RUS75633.1 - 0.026 14.0 0.1 0.031 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) RA PF00788.23 RUS75634.1 - 7.3e-36 122.7 2.7 5.7e-17 62.1 0.0 3.2 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 RUS75634.1 - 5e-33 113.5 1.9 5e-33 113.5 1.9 2.3 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 RUS75634.1 - 2.8e-16 59.6 0.7 6.1e-16 58.5 0.7 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS75634.1 - 2.9e-10 39.8 0.2 6.7e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS75634.1 - 1.4e-05 25.3 0.3 4.6e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 PDZ domain MAS20 PF02064.15 RUS75634.1 - 0.0048 17.0 1.6 0.0048 17.0 1.6 7.7 6 2 3 9 9 9 1 MAS20 protein import receptor APG6_N PF17675.1 RUS75635.1 - 7e-05 23.4 20.6 7e-05 23.4 20.6 51.5 10 10 37 52 52 52 9 Apg6 coiled-coil region MAD PF05557.13 RUS75635.1 - 0.00041 18.9 52.2 0.00041 18.9 52.2 28.7 6 5 20 27 27 27 6 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 RUS75635.1 - 0.00045 20.2 11.8 0.00045 20.2 11.8 50.3 12 9 39 53 53 53 14 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALS2CR8 PF15299.6 RUS75636.1 - 4.5e-42 144.4 0.0 8.2e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 MTABC_N PF16185.5 RUS75638.1 - 1.4e-63 214.6 12.9 1.4e-63 214.6 12.9 1.8 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_tran PF00005.27 RUS75638.1 - 9.8e-35 120.0 0.0 1.7e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RUS75638.1 - 8.1e-32 111.0 16.9 8.1e-32 111.0 16.9 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 RUS75638.1 - 4.2e-07 29.6 0.7 7.1e-06 25.6 0.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RUS75638.1 - 0.0022 18.4 0.1 0.0064 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS75638.1 - 0.0071 16.1 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS75638.1 - 0.011 15.6 0.0 0.048 13.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 RUS75638.1 - 0.014 15.5 0.2 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 RUS75638.1 - 0.015 15.8 0.3 0.33 11.4 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS75638.1 - 0.015 15.6 0.0 0.049 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RUS75638.1 - 0.018 15.0 0.1 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 RUS75638.1 - 0.024 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RUS75638.1 - 0.035 14.2 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 RUS75638.1 - 0.055 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 RUS75638.1 - 0.06 13.8 0.1 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RUS75638.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 RUS75638.1 - 0.094 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 RUS75638.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 RUS75638.1 - 0.11 12.8 0.2 1.1 9.5 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Neur_chan_memb PF02932.16 RUS75638.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.18 RUS75639.1 - 9.5e-67 225.5 21.5 9.5e-67 225.5 21.5 2.0 2 1 0 2 2 2 1 Nucleoside transporter COesterase PF00135.28 RUS75640.1 - 3.7e-108 362.6 0.0 4.2e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS75640.1 - 2.9e-08 33.8 1.4 1.7e-07 31.3 1.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold HTH_Crp_2 PF13545.6 RUS75640.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Peptidase_S9 PF00326.21 RUS75640.1 - 0.12 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS75640.1 - 0.15 10.9 0.7 0.84 8.4 0.7 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 RUS75641.1 - 1.7e-25 89.7 22.6 9e-25 87.3 18.8 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS75641.1 - 5.1e-22 78.4 16.1 1.1e-21 77.2 16.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 RUS75641.1 - 5.3e-07 28.5 11.2 5.3e-07 28.5 11.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Ldl_recept_a PF00057.18 RUS75642.1 - 1.7e-18 66.5 34.5 4e-13 49.3 14.0 2.6 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A YL1 PF05764.13 RUS75642.1 - 2.2 8.3 8.7 1.4 9.0 0.2 2.0 2 0 0 2 2 2 0 YL1 nuclear protein CBM_14 PF01607.24 RUS75644.1 - 1.4e-17 63.6 22.2 2.6e-08 33.9 2.2 3.2 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain Collagen PF01391.18 RUS75645.1 - 2.9e-62 206.3 0.0 2.1e-05 24.2 0.0 12.5 3 2 2 6 6 6 6 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 RUS75646.1 - 1.3e-57 195.2 0.0 1.7e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75646.1 - 1.6e-41 142.3 0.0 2.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS75646.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RUS75646.1 - 1.7e-05 24.0 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 RUS75646.1 - 0.0028 16.7 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS75646.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS75646.1 - 0.031 13.1 0.0 0.068 11.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase T2SSB PF16537.5 RUS75646.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B XTBD PF11952.8 RUS75647.1 - 6.8e-17 61.0 0.5 1.3e-16 60.2 0.5 1.5 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD G-patch PF01585.23 RUS75647.1 - 2.2e-11 43.5 4.1 3.9e-11 42.7 4.1 1.4 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 RUS75647.1 - 5.6e-09 35.9 0.7 1.3e-08 34.7 0.7 1.5 1 0 0 1 1 1 1 R3H domain dsrm PF00035.26 RUS75647.1 - 2.4e-07 31.3 0.0 7.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.7 RUS75647.1 - 5.3e-05 23.2 2.0 6.6e-05 22.9 0.8 1.8 2 0 0 2 2 2 1 G-patch domain UCH PF00443.29 RUS75648.1 - 4.2e-72 242.7 0.0 5.5e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS75648.1 - 4.1e-14 52.9 0.2 1.4e-07 31.4 0.2 3.1 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RUS75648.1 - 1.6e-10 41.4 0.1 1.1e-09 38.8 0.0 2.3 2 0 0 2 2 2 1 DUSP domain Ubiquitin_3 PF14836.6 RUS75648.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3785 PF12653.7 RUS75648.1 - 0.035 14.2 2.2 0.4 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3785) DNA_RNApol_7kD PF03604.13 RUS75648.1 - 4.3 7.1 7.6 0.18 11.5 0.2 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Collagen PF01391.18 RUS75651.1 - 0.00059 19.5 7.2 0.00059 19.5 7.2 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) HSBP1 PF06825.12 RUS75651.1 - 0.0024 17.7 0.9 0.0046 16.8 0.9 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Spectrin PF00435.21 RUS75651.1 - 0.039 14.4 3.2 0.5 10.9 0.5 2.6 2 0 0 2 2 2 0 Spectrin repeat Ufd2P_core PF10408.9 RUS75651.1 - 0.06 11.9 0.5 0.084 11.5 0.5 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF601 PF04642.12 RUS75651.1 - 0.26 10.7 11.1 0.05 13.1 5.5 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF601 p450 PF00067.22 RUS75653.1 - 3.8e-94 316.0 0.5 5e-94 315.6 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arif-1 PF06770.11 RUS75654.1 - 0.07 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) TBCC PF07986.12 RUS75655.1 - 1.8e-31 108.3 0.0 3.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 RUS75655.1 - 3.8e-06 26.6 0.2 6.2e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Syntaxin PF00804.25 RUS75656.1 - 1.5e-63 214.1 17.8 2.4e-63 213.5 17.8 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 RUS75656.1 - 1.1e-18 66.9 12.8 3.3e-18 65.4 3.8 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 RUS75656.1 - 2.8e-11 43.7 7.3 2.8e-11 43.7 7.3 2.4 1 1 1 2 2 2 1 Syntaxin-like protein AAA_13 PF13166.6 RUS75656.1 - 0.00016 20.5 14.3 0.0002 20.2 14.3 1.1 1 0 0 1 1 1 1 AAA domain SRP68 PF16969.5 RUS75656.1 - 0.00034 19.7 3.2 0.00034 19.7 3.2 1.6 2 0 0 2 2 2 1 RNA-binding signal recognition particle 68 Ferritin PF00210.24 RUS75656.1 - 0.0037 17.2 1.9 0.0037 17.2 1.9 1.9 2 0 0 2 2 2 1 Ferritin-like domain Allexi_40kDa PF05549.11 RUS75656.1 - 0.009 15.6 7.2 0.016 14.7 2.0 2.2 2 0 0 2 2 2 1 Allexivirus 40kDa protein T2SSF PF00482.23 RUS75656.1 - 0.019 14.9 5.9 0.23 11.4 1.5 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Lzipper-MIP1 PF14389.6 RUS75656.1 - 0.019 15.2 1.7 0.37 11.1 0.0 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ETRAMP PF09716.10 RUS75656.1 - 0.023 14.8 0.5 0.023 14.8 0.5 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF5383 PF17355.2 RUS75656.1 - 0.057 13.8 0.5 0.057 13.8 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5383) COG2 PF06148.11 RUS75656.1 - 0.082 13.0 13.1 1.1 9.4 4.1 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 RUS75656.1 - 0.09 13.3 0.5 0.09 13.3 0.5 3.5 2 2 1 3 3 3 0 YtxH-like protein WXG100 PF06013.12 RUS75656.1 - 0.1 12.8 5.5 7.4 6.9 0.2 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG MCPsignal PF00015.21 RUS75656.1 - 0.11 12.4 13.5 0.72 9.6 0.8 2.9 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TraF_2 PF13729.6 RUS75656.1 - 0.15 11.4 6.6 0.11 11.9 2.9 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein TLV_coat PF00429.19 RUS75656.1 - 0.16 10.6 0.8 0.29 9.7 0.0 1.7 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) SKA1 PF07160.12 RUS75656.1 - 0.16 11.8 13.7 1.2 8.9 2.2 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF848 PF05852.11 RUS75656.1 - 0.17 12.0 11.5 0.1 12.7 5.3 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sigma_reg_N PF13800.6 RUS75656.1 - 0.25 11.7 5.8 0.63 10.4 5.8 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Occludin_ELL PF07303.13 RUS75656.1 - 0.28 11.9 12.8 8.3 7.2 4.9 3.1 2 1 0 2 2 2 0 Occludin homology domain Sec34 PF04136.15 RUS75656.1 - 0.38 10.6 10.5 0.79 9.6 4.4 2.6 2 1 0 2 2 2 0 Sec34-like family DUF5345 PF17280.2 RUS75656.1 - 0.41 10.6 4.1 0.47 10.5 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) COG5 PF10392.9 RUS75656.1 - 0.51 10.5 8.2 2.5 8.3 2.8 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2207 PF09972.9 RUS75656.1 - 0.52 9.0 4.3 0.59 8.8 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Syntaxin-6_N PF09177.11 RUS75656.1 - 0.52 10.9 11.1 0.16 12.6 5.1 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Nup54 PF13874.6 RUS75656.1 - 0.57 10.3 14.1 2.8 8.1 8.1 3.1 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 RUS75656.1 - 1.1 9.3 14.8 1.6 8.8 6.5 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF1910 PF08928.10 RUS75656.1 - 1.6 8.7 9.3 0.12 12.4 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) Mur_ligase_M PF08245.12 RUS75656.1 - 2.2 8.3 7.7 0.22 11.5 0.5 2.2 2 0 0 2 2 2 0 Mur ligase middle domain DUF2203 PF09969.9 RUS75656.1 - 2.9 8.6 14.8 6.4 7.5 1.1 3.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5407 PF17401.2 RUS75656.1 - 4 7.8 6.9 3.8 7.8 2.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5407) Synaptobrevin PF00957.21 RUS75656.1 - 4.7 7.1 19.7 0.027 14.2 3.4 3.2 2 1 1 3 3 3 0 Synaptobrevin DUF2779 PF11074.8 RUS75656.1 - 6.1 7.3 9.3 57 4.2 9.0 2.4 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) ISG65-75 PF11727.8 RUS75656.1 - 6.4 5.9 14.4 0.26 10.5 5.2 2.3 2 1 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.12 RUS75656.1 - 6.4 6.8 15.3 3 7.9 2.4 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 RUS75656.1 - 8.4 6.6 11.3 1.5 9.0 1.0 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal YojJ PF10372.9 RUS75656.1 - 9.5 6.4 8.9 11 6.2 1.2 3.8 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus UQ_con PF00179.26 RUS75657.1 - 1.2e-42 144.9 0.1 1.5e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS75657.1 - 1.4e-05 24.8 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RUS75657.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 RUS75657.1 - 0.00046 20.5 0.3 0.00088 19.5 0.2 1.5 1 1 0 1 1 1 1 RWD domain Cgr1 PF03879.14 RUS75658.1 - 3.3e-16 59.6 29.2 3.3e-16 59.6 29.2 1.5 2 0 0 2 2 2 1 Cgr1 family Macoilin PF09726.9 RUS75658.1 - 0.32 9.5 13.6 0.33 9.5 13.6 1.1 1 0 0 1 1 1 0 Macoilin family UPF0122 PF04297.14 RUS75658.1 - 0.94 9.8 12.6 0.089 13.0 4.8 2.2 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DUF3810 PF12725.7 RUS75658.1 - 2.9 7.2 4.5 3.8 6.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WBS_methylT PF12589.8 RUS75659.1 - 2.5e-18 66.6 5.2 5.4e-18 65.5 5.2 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 RUS75659.1 - 4.7e-10 40.0 0.0 8.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS75659.1 - 6.3e-10 39.6 0.0 1.2e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS75659.1 - 1e-05 26.2 0.1 6.2e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS75659.1 - 1.1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS75659.1 - 0.00034 20.5 0.0 0.00061 19.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 RUS75659.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 RUS75659.1 - 0.034 14.1 0.3 0.071 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 RUS75659.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TFIIA PF03153.13 RUS75660.1 - 9.3e-10 39.1 63.7 9.3e-10 39.1 63.7 4.2 2 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 RUS75660.1 - 0.028 14.5 0.0 0.028 14.5 0.0 5.1 1 1 2 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L37 PF08561.10 RUS75660.1 - 6.7 7.3 24.5 1.3 9.6 2.4 3.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Tgi2PP PF18250.1 RUS75661.1 - 0.0017 18.5 4.0 1.1e+02 3.1 0.0 6.3 1 1 6 8 8 8 0 Effector immunity protein Tgi2PP LRR_10 PF18805.1 RUS75661.1 - 0.0068 16.0 4.8 15 5.3 0.1 4.3 1 1 5 6 6 6 4 Leucine-rich repeat Entericidin PF08085.11 RUS75661.1 - 0.031 14.3 17.9 2e+02 2.2 0.0 8.3 9 0 0 9 9 9 0 Entericidin EcnA/B family CorA PF01544.18 RUS75663.1 - 0.11 11.8 0.8 0.2 10.9 0.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ELFV_dehydrog_N PF02812.18 RUS75664.1 - 5e-12 45.8 0.1 8.8e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF4817 PF16087.5 RUS75664.1 - 0.014 15.2 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) rve PF00665.26 RUS75665.1 - 2.9e-13 50.1 0.0 4.5e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Integrase core domain Integrase_H2C2 PF17921.1 RUS75665.1 - 0.0076 16.3 0.1 0.0076 16.3 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain SEFIR PF08357.11 RUS75666.1 - 1.8e-29 103.0 0.1 2.4e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 SEFIR domain DUF2207 PF09972.9 RUS75666.1 - 0.0069 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 RUS75667.1 - 5.8e-22 78.3 6.6 8.9e-13 48.2 4.0 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Ecm33 PF12454.8 RUS75667.1 - 0.11 12.6 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TatC PF00902.18 RUS75667.1 - 0.59 9.9 6.7 0.24 11.2 2.5 2.3 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Sporozoite_P67 PF05642.11 RUS75668.1 - 0.053 11.6 1.0 0.06 11.4 1.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Roughex PF06020.11 RUS75668.1 - 0.13 11.3 3.7 0.16 11.1 3.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Cwf_Cwc_15 PF04889.12 RUS75668.1 - 0.38 10.4 13.7 0.51 10.0 13.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RUS75668.1 - 4.8 6.4 18.4 6.4 6.0 18.4 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 RUS75668.1 - 5.7 5.0 11.0 7.1 4.7 11.0 1.0 1 0 0 1 1 1 0 Nop14-like family UCH PF00443.29 RUS75669.1 - 9.4e-69 231.8 0.0 1.7e-68 230.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CS PF04969.16 RUS75669.1 - 4.1e-18 66.2 6.9 1.2e-08 35.8 0.7 2.8 2 0 0 2 2 2 2 CS domain UCH_1 PF13423.6 RUS75669.1 - 9e-13 48.5 4.6 0.00053 19.7 0.0 4.9 5 0 0 5 5 5 3 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 RUS75669.1 - 1.5e-07 31.3 18.2 1.5e-07 31.3 18.2 2.7 3 0 0 3 3 3 1 MYND finger zf-ribbon_3 PF13248.6 RUS75669.1 - 0.015 14.7 1.1 5 6.7 0.1 3.1 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 RUS75669.1 - 0.032 14.3 0.1 3 7.9 0.0 3.0 2 0 0 2 2 2 0 CpXC protein zf-C6H2 PF15801.5 RUS75669.1 - 2.2 8.7 20.8 5.3 7.4 12.6 3.6 3 1 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Usp PF00582.26 RUS75670.1 - 6.3e-27 94.8 0.0 7.3e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Galactosyl_T PF01762.21 RUS75671.1 - 1.3e-43 149.1 0.0 1.7e-42 145.4 0.0 2.2 1 1 0 1 1 1 1 Galactosyltransferase 7tm_1 PF00001.21 RUS75672.1 - 1.5e-11 44.1 0.7 1.9e-11 43.8 0.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Shisa PF13908.6 RUS75673.1 - 0.0012 19.1 0.0 0.0012 19.1 0.0 3.4 4 1 0 4 4 4 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 RUS75673.1 - 0.0012 18.5 4.8 0.0029 17.3 4.8 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 RUS75673.1 - 0.015 16.2 0.1 0.015 16.2 0.1 3.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 RUS75673.1 - 0.058 13.2 0.6 2.8 7.8 0.2 3.1 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM154 PF15102.6 RUS75673.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 TMEM154 protein family eIF3_subunit PF08597.10 RUS75673.1 - 1.3 8.9 33.6 3.1 7.6 33.6 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Methyltransf_11 PF08241.12 RUS75674.1 - 1.2e-19 70.7 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS75674.1 - 7.3e-18 65.1 0.0 1.6e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS75674.1 - 1.7e-10 40.9 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS75674.1 - 1e-07 32.6 0.0 1.9e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS75674.1 - 4.5e-07 29.4 0.0 7.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS75674.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RUS75674.1 - 2.3e-06 27.3 0.1 3.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 RUS75674.1 - 0.00041 19.4 0.0 0.00058 19.0 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 RUS75674.1 - 0.00099 18.7 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RUS75674.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 RUS75674.1 - 0.014 14.9 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 RUS75674.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.16 RUS75674.1 - 0.027 13.0 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_zinc_N PF00107.26 RUS75674.1 - 0.028 14.4 0.0 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase CMAS PF02353.20 RUS75674.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF4318 PF14201.6 RUS75674.1 - 0.13 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) Methyltransf_8 PF05148.15 RUS75674.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase NodS PF05401.11 RUS75674.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) HIGH_NTase1_ass PF16581.5 RUS75675.1 - 0.014 15.4 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Chordopox_A13L PF05961.11 RUS75675.1 - 0.13 12.5 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF1676 PF07898.13 RUS75676.1 - 0.0037 17.3 1.7 0.0037 17.3 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) Orf78 PF06024.12 RUS75676.1 - 0.14 12.5 0.3 0.14 12.5 0.3 2.7 3 0 0 3 3 3 0 Orf78 (ac78) EF-hand_7 PF13499.6 RUS75677.1 - 1e-05 25.9 3.8 0.014 15.9 0.0 5.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS75677.1 - 0.0045 16.8 0.4 0.25 11.4 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS75677.1 - 0.14 11.8 0.2 2 8.2 0.1 3.0 2 0 0 2 2 2 0 EF hand FAM183 PF14886.6 RUS75678.1 - 0.00022 21.9 1.2 0.0015 19.3 1.2 2.1 1 1 0 1 1 1 1 FAM183A and FAM183B related DUF4541 PF15074.6 RUS75678.1 - 0.0032 18.0 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) F-box-like PF12937.7 RUS75679.1 - 6.6e-14 51.5 1.4 7.8e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS75679.1 - 9.1e-10 38.2 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Hemerythrin PF01814.23 RUS75679.1 - 2.5e-06 28.1 4.5 0.0099 16.5 0.4 2.6 2 1 1 3 3 3 2 Hemerythrin HHE cation binding domain YfkB PF08756.10 RUS75679.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 YfkB-like domain 5_nucleotid_C PF02872.18 RUS75680.1 - 4e-42 144.1 0.0 6.3e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RUS75680.1 - 1.4e-08 35.4 0.1 2.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ActA PF05058.12 RUS75680.1 - 0.24 9.7 0.0 0.34 9.2 0.0 1.1 1 0 0 1 1 1 0 ActA Protein TIP41 PF04176.13 RUS75681.1 - 5.9e-64 214.7 0.0 7.2e-64 214.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family SAP18 PF06487.12 RUS75682.1 - 1.2e-40 138.9 0.0 1.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Apolipoprotein PF01442.18 RUS75683.1 - 5e-09 36.3 0.1 3.2e-05 23.9 0.0 3.1 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 RUS75683.1 - 0.00017 21.7 0.3 0.051 13.7 0.0 3.1 3 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Chlorosome_CsmC PF11098.8 RUS75683.1 - 0.00082 19.4 7.3 0.15 12.0 0.4 3.1 3 0 0 3 3 3 2 Chlorosome envelope protein C DUF4795 PF16043.5 RUS75683.1 - 0.0013 18.3 1.7 0.054 13.1 2.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) Senescence PF06911.12 RUS75683.1 - 0.0026 18.1 2.9 0.029 14.7 0.4 2.7 3 0 0 3 3 3 1 Senescence-associated protein Tape_meas_lam_C PF09718.10 RUS75683.1 - 0.0031 17.6 6.3 2.5 8.3 0.0 3.9 3 2 0 3 3 3 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin PF05597.11 RUS75683.1 - 0.046 13.7 3.6 0.55 10.2 1.1 3.2 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 RUS75683.1 - 0.057 14.0 4.8 2.1 9.0 0.0 3.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EspB PF05802.11 RUS75683.1 - 0.063 13.3 9.9 0.36 10.8 0.6 2.6 3 0 0 3 3 3 0 Enterobacterial EspB protein DUF948 PF06103.11 RUS75683.1 - 0.087 13.1 5.6 3.4 8.0 0.1 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Carbpep_Y_N PF05388.11 RUS75683.1 - 0.098 13.2 0.1 10 6.7 0.0 3.0 3 1 0 3 3 3 0 Carboxypeptidase Y pro-peptide Phasin_2 PF09361.10 RUS75683.1 - 0.1 12.9 0.4 7 7.0 0.1 3.1 3 1 0 3 3 3 0 Phasin protein ATG_C PF09333.11 RUS75683.1 - 0.11 12.9 1.7 10 6.5 0.3 4.1 3 2 1 4 4 3 0 Autophagy-related protein C terminal domain DUF1664 PF07889.12 RUS75683.1 - 0.12 12.4 0.0 1.5 8.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ApoO PF09769.9 RUS75683.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein O Baculo_PEP_C PF04513.12 RUS75683.1 - 0.13 12.3 0.0 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 RUS75683.1 - 0.2 12.2 20.6 3.7 8.1 2.2 5.9 3 3 0 3 3 2 0 YtxH-like protein DUF1451 PF07295.11 RUS75683.1 - 0.48 10.4 1.4 1 9.4 0.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF4175 PF13779.6 RUS75683.1 - 1 7.1 8.3 0.56 8.1 4.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4175) Tom22 PF04281.13 RUS75683.1 - 2.1 8.1 8.3 0.93 9.3 5.2 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF5610 PF18433.1 RUS75683.1 - 3.4 8.2 15.9 3.3 8.2 1.4 4.0 3 1 0 4 4 4 0 Domain of unknown function (DUF5610) COG2 PF06148.11 RUS75683.1 - 5.1 7.2 6.1 7.9 6.6 0.4 3.5 3 3 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Synuclein PF01387.17 RUS75683.1 - 5.5 7.2 15.0 0.16 12.1 2.5 2.9 2 1 1 3 3 3 0 Synuclein DUF2884 PF11101.8 RUS75683.1 - 7.1 6.1 9.2 3 7.3 0.8 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2884) Reeler PF02014.16 RUS75684.1 - 9.9e-06 26.3 0.0 2.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Reeler domain Pkinase PF00069.25 RUS75685.1 - 1.1e-67 228.2 0.1 1.2e-66 224.8 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75685.1 - 4.9e-43 147.3 0.1 1.1e-42 146.1 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS75685.1 - 2.2e-09 37.0 0.0 6.7e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RUS75685.1 - 0.00066 18.6 0.0 0.0021 16.9 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS75685.1 - 0.0094 15.3 0.6 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family T3SS_basalb_I PF17001.5 RUS75685.1 - 2.4 8.8 6.8 0.59 10.8 1.6 2.9 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Pkinase PF00069.25 RUS75686.1 - 3.7e-72 242.9 0.3 4.8e-72 242.5 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75686.1 - 7.4e-44 150.0 0.1 1.1e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS75686.1 - 9.4e-10 38.3 0.2 3.3e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RUS75686.1 - 7.1e-07 28.3 0.3 1.5e-06 27.3 0.3 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS75686.1 - 3.2e-06 26.7 0.1 5.2e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS75686.1 - 0.0047 16.9 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS75686.1 - 0.011 14.6 0.4 0.021 13.8 0.4 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF1439 PF07273.12 RUS75686.1 - 0.11 12.3 1.2 0.87 9.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1439) SMAP PF15477.6 RUS75687.1 - 2e-13 51.1 2.9 2e-13 51.1 2.9 2.5 2 1 0 2 2 2 1 Small acidic protein family DUF1373 PF07117.11 RUS75687.1 - 0.0069 16.4 1.4 0.01 15.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) Ribosomal_L44 PF00935.19 RUS75688.1 - 9.8e-36 122.1 11.4 1.5e-35 121.5 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 WD40 PF00400.32 RUS75689.1 - 2.1e-21 75.8 25.6 1.8e-05 25.4 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RUS75689.1 - 0.00012 21.0 0.4 0.022 13.5 0.1 3.1 1 1 1 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 RUS75689.1 - 0.00049 20.3 6.5 2.1 8.7 0.4 4.3 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS75689.1 - 0.0014 17.4 8.0 2.6 6.6 0.1 4.6 1 1 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 RUS75689.1 - 0.0018 18.2 0.9 0.01 15.7 0.5 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RUS75689.1 - 0.0026 16.8 0.4 4.1 6.3 0.0 3.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Itfg2 PF15907.5 RUS75689.1 - 0.0029 16.7 0.9 0.01 14.9 0.5 2.0 1 1 1 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 MFS_1 PF07690.16 RUS75690.1 - 7.3e-14 51.5 14.6 7.3e-14 51.5 14.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 RUS75690.1 - 0.13 12.0 4.7 1.5 8.7 0.1 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Prenyltransf PF01255.19 RUS75691.1 - 0.00078 19.0 0.0 0.0099 15.4 0.0 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase p450 PF00067.22 RUS75692.1 - 2.9e-89 300.0 0.0 3.3e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 RUS75693.1 - 1.1e-29 102.9 1.6 6.1e-14 52.2 0.1 3.6 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 RUS75693.1 - 2.5e-23 82.4 7.9 6e-07 30.0 0.3 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 RUS75693.1 - 3e-13 49.7 0.4 1.1e-09 38.3 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS75693.1 - 2.5e-12 47.2 0.1 1.1e-11 45.1 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS75693.1 - 4e-11 42.8 0.8 1.6e-06 28.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RUS75693.1 - 1.5e-09 37.3 0.3 6.1e-06 26.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RUS75693.1 - 5.3e-09 36.4 0.9 4.7e-05 23.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 RUS75693.1 - 0.006 16.4 14.9 0.26 11.2 0.2 5.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Pec_lyase_N PF04431.13 RUS75693.1 - 0.019 15.2 0.1 0.077 13.2 0.1 2.1 1 0 0 1 1 1 0 Pectate lyase, N terminus ATE_C PF04377.15 RUS75694.1 - 4.7e-49 166.5 1.1 1.1e-48 165.3 1.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 RUS75694.1 - 9.5e-28 96.4 7.0 9.5e-28 96.4 7.0 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Macoilin PF09726.9 RUS75694.1 - 0.09 11.3 4.5 0.11 11.0 4.5 1.1 1 0 0 1 1 1 0 Macoilin family EF-hand_7 PF13499.6 RUS75697.1 - 2.7e-08 34.1 0.3 9.2e-07 29.2 0.7 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS75697.1 - 5e-07 28.8 0.2 0.00078 18.8 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS75697.1 - 5.8e-07 28.9 0.6 0.0003 20.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 RUS75697.1 - 7.5e-06 25.7 0.6 0.013 15.3 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS75697.1 - 0.00094 18.6 2.5 0.0012 18.3 0.0 2.4 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 RUS75698.1 - 5e-10 39.7 3.6 0.08 13.4 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS75698.1 - 6.6e-10 38.1 3.5 0.0018 18.1 0.1 5.7 5 1 0 5 5 5 2 EF-hand domain EF-hand_11 PF08976.11 RUS75698.1 - 4e-08 34.1 2.9 0.22 12.4 0.1 5.1 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 RUS75698.1 - 9.7e-07 27.9 3.3 0.64 9.7 0.2 5.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 RUS75698.1 - 0.012 15.4 6.4 1.7 8.6 0.2 5.2 5 2 1 6 6 6 0 EF-hand domain pair Glycos_trans_3N PF02885.17 RUS75698.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF3439 PF11921.8 RUS75698.1 - 0.37 10.8 6.7 0.91 9.5 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 7tm_1 PF00001.21 RUS75699.1 - 1.3e-37 129.5 14.0 1.9e-37 129.0 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS75700.1 - 7.3e-36 123.8 22.0 9e-36 123.5 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sru PF10322.9 RUS75700.1 - 0.85 8.9 27.3 4.7 6.4 27.3 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Pkinase PF00069.25 RUS75701.1 - 2.1e-39 135.5 0.0 4.8e-38 131.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75701.1 - 4e-24 85.3 0.0 5.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS75701.1 - 0.0021 17.5 0.4 0.0036 16.7 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS75701.1 - 0.0023 16.8 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS75701.1 - 0.0058 16.6 1.5 0.17 11.8 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS75701.1 - 0.065 12.5 0.0 0.64 9.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 RUS75701.1 - 0.068 12.8 0.1 0.81 9.3 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 7tm_1 PF00001.21 RUS75702.1 - 5.7e-18 65.2 7.8 8.7e-18 64.6 7.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS75702.1 - 2.5e-05 23.8 13.1 3.4e-05 23.4 13.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS75702.1 - 0.00067 19.0 14.0 0.0011 18.4 14.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS75702.1 - 0.00086 19.1 7.3 0.0011 18.8 7.3 1.1 1 0 0 1 1 1 1 Olfactory receptor G_glu_transpept PF01019.21 RUS75704.1 - 4.4e-163 543.7 0.0 5.1e-163 543.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pribosyltran PF00156.27 RUS75704.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain ETRAMP PF09716.10 RUS75704.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TIR PF01582.20 RUS75705.1 - 1.8e-28 99.5 0.0 6.3e-28 97.8 0.0 1.9 2 0 0 2 2 2 1 TIR domain TIR_2 PF13676.6 RUS75705.1 - 2.5e-20 73.2 0.0 5.5e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 RUS75705.1 - 1 9.7 4.1 0.61 10.4 0.4 2.6 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Toxin_3 PF00537.18 RUS75705.1 - 1.3 9.2 14.2 7.8 6.8 1.0 2.6 2 0 0 2 2 2 0 Scorpion toxin-like domain AhpC-TSA PF00578.21 RUS75706.1 - 6.7e-38 129.4 0.0 1.2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS75706.1 - 5.6e-14 52.1 0.0 9.4e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RUS75706.1 - 5.2e-13 48.6 0.1 1.2e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_4 PF12799.7 RUS75708.1 - 2.3e-06 27.9 16.5 0.00088 19.6 0.9 5.6 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS75708.1 - 1.1 9.4 14.0 57 4.2 0.1 5.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 RUS75708.1 - 4.5 7.1 10.6 1.3 8.9 0.3 3.7 2 1 2 4 4 4 0 Leucine rich repeat Thioredoxin PF00085.20 RUS75710.1 - 7e-09 35.6 0.0 1.1e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 RUS75710.1 - 4e-08 33.4 0.3 0.0027 17.6 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS75710.1 - 0.00066 20.0 0.6 1.1 9.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RUS75710.1 - 0.00074 19.4 0.1 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family SNAD4 PF18750.1 RUS75710.1 - 0.041 14.0 0.4 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Redoxin PF08534.10 RUS75710.1 - 0.09 12.5 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Redoxin HLH PF00010.26 RUS75711.1 - 1.8e-14 53.4 1.5 3.3e-14 52.6 0.8 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain SNF2_N PF00176.23 RUS75712.1 - 4.6e-44 150.6 0.0 7.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS75712.1 - 3.8e-14 53.0 0.0 2.2e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 RUS75712.1 - 0.00011 22.2 0.1 0.00046 20.3 0.1 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Img2 PF05046.14 RUS75714.1 - 0.081 13.2 0.1 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) MAPEG PF01124.18 RUS75715.1 - 2.8e-25 88.7 1.9 3.2e-25 88.5 1.9 1.0 1 0 0 1 1 1 1 MAPEG family zf-C2H2 PF00096.26 RUS75716.1 - 1.3e-48 160.8 127.7 0.00022 21.5 0.3 17.3 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS75716.1 - 3e-40 133.4 126.1 0.01 16.6 0.4 17.4 17 0 0 17 17 17 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS75716.1 - 1.7e-13 50.4 70.5 0.0014 18.9 0.2 14.1 15 0 0 15 15 15 6 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS75716.1 - 5.8e-13 48.6 132.1 0.0005 20.4 0.5 18.4 21 1 0 21 21 21 8 Zinc-finger double domain zf-met PF12874.7 RUS75716.1 - 1.3e-05 25.4 83.4 0.0049 17.2 0.5 14.6 16 0 0 16 16 16 5 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 RUS75716.1 - 0.011 15.8 2.6 0.011 15.8 2.6 4.4 5 0 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-BED PF02892.15 RUS75716.1 - 0.019 15.0 0.5 0.019 15.0 0.5 11.6 13 2 0 13 13 13 0 BED zinc finger Actin_micro PF17003.5 RUS75716.1 - 0.16 11.1 34.0 2.4 7.2 0.0 8.4 4 1 2 8 8 8 0 Putative actin-like family zf_C2H2_6 PF18450.1 RUS75716.1 - 4.8 7.0 12.3 0.08 12.7 1.5 3.5 3 0 0 3 3 3 0 Zinc Finger domain Transketolase_N PF00456.21 RUS75717.1 - 2.7e-49 167.9 0.1 4.8e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RUS75717.1 - 8.7e-38 129.8 0.0 1.5e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RUS75717.1 - 1.5e-29 102.4 0.5 8.8e-29 99.9 0.2 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 RUS75717.1 - 4.9e-09 35.5 0.0 7.5e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RUS75717.1 - 1.6e-06 27.6 0.0 3.1e-05 23.3 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RUS75717.1 - 1.8e-05 24.6 0.3 0.00073 19.4 0.0 3.4 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 RUS75717.1 - 0.00029 19.7 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain Transketolase_N PF00456.21 RUS75718.1 - 1.5e-22 80.0 0.5 1.4e-10 40.7 0.1 2.1 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RUS75718.1 - 1.3e-20 73.8 0.0 2.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RUS75718.1 - 4.8e-18 65.2 0.2 9.1e-18 64.3 0.2 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 RUS75718.1 - 0.00061 19.6 0.2 0.0038 17.0 0.1 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 RUS75718.1 - 0.0033 16.7 0.0 0.46 9.6 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 RUS75718.1 - 0.018 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component AA_permease_2 PF13520.6 RUS75718.1 - 4 6.1 24.1 6 5.6 24.1 1.2 1 0 0 1 1 1 0 Amino acid permease Caveolin PF01146.17 RUS75719.1 - 6.8e-44 149.1 0.7 8e-44 148.8 0.7 1.0 1 0 0 1 1 1 1 Caveolin TRAP-gamma PF07074.12 RUS75719.1 - 0.12 11.9 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) tRNA_edit PF04073.15 RUS75720.1 - 1.7e-22 79.8 0.2 4.8e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 Aminoacyl-tRNA editing domain DUF2161 PF09929.9 RUS75720.1 - 0.19 11.8 3.6 2.3 8.3 0.5 2.5 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) zf-C2H2 PF00096.26 RUS75721.1 - 2e-38 128.7 66.9 8.8e-07 29.1 2.2 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS75721.1 - 3.8e-30 101.9 62.7 0.00012 22.6 0.1 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS75721.1 - 3.3e-24 84.2 52.9 3.3e-07 30.4 3.1 9.5 9 1 0 9 9 9 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS75721.1 - 1.3e-13 50.5 58.1 0.00088 19.2 1.0 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS75721.1 - 1.3e-09 38.1 29.0 0.064 13.6 0.2 7.8 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS75721.1 - 3e-08 33.8 37.9 0.018 15.4 0.1 8.2 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS75721.1 - 1.1e-05 25.1 54.2 0.036 13.8 0.0 8.0 8 0 0 8 8 8 6 zinc-finger C2H2-type Ta0938 PF11494.8 RUS75721.1 - 0.0017 18.6 8.2 0.25 11.6 0.5 4.2 3 1 1 4 4 4 1 Ta0938 zf-C2H2_9 PF16293.5 RUS75721.1 - 0.014 15.2 21.7 0.38 10.6 0.4 5.6 4 2 3 7 7 7 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 RUS75721.1 - 0.021 15.6 17.1 0.61 10.9 1.9 4.4 1 1 1 3 3 3 0 zinc-ribbon family zf-C2HC_2 PF13913.6 RUS75721.1 - 0.024 14.5 29.7 0.37 10.7 0.1 6.8 7 0 0 7 7 6 0 zinc-finger of a C2HC-type BolA PF01722.18 RUS75721.1 - 0.027 14.8 6.5 12 6.3 0.2 4.7 4 1 1 5 5 5 0 BolA-like protein zf-C2H2_2 PF12756.7 RUS75721.1 - 0.046 14.0 41.5 0.34 11.3 0.2 7.7 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RUS75721.1 - 0.14 12.6 0.1 0.14 12.6 0.1 6.2 3 2 4 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2180 PF09947.9 RUS75721.1 - 0.27 11.2 19.7 6.1 6.9 0.8 5.2 5 3 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) Zn-ribbon_8 PF09723.10 RUS75721.1 - 4.3 7.5 30.4 2.9 8.1 0.7 5.9 6 1 1 7 7 6 0 Zinc ribbon domain PHF5 PF03660.14 RUS75721.1 - 5.2 7.3 13.8 1.4 9.1 2.1 3.3 3 1 0 3 3 3 0 PHF5-like protein Ribosomal_S14 PF00253.21 RUS75721.1 - 7.9 6.3 22.9 1.1 9.1 0.4 5.1 5 1 1 6 6 6 0 Ribosomal protein S14p/S29e Ank_2 PF12796.7 RUS75722.1 - 1.4e-28 99.3 0.7 7e-15 55.4 0.1 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS75722.1 - 5.3e-28 97.0 0.1 3.5e-11 43.4 0.0 3.7 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS75722.1 - 2.9e-26 88.6 0.6 3.6e-05 23.8 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 RUS75722.1 - 1.8e-24 85.0 4.9 6e-06 26.5 0.0 5.6 4 1 1 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 RUS75722.1 - 3e-18 65.6 0.9 8.8e-07 29.1 0.0 4.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Pns11_12 PF17464.2 RUS75722.1 - 2.9 7.6 15.7 0.18 11.5 8.9 2.1 2 0 0 2 2 2 0 Non-structural protein 11 and 12 zf-C2H2 PF00096.26 RUS75723.1 - 1.5e-31 107.1 76.7 7.9e-05 22.9 1.6 11.0 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS75723.1 - 2.8e-24 83.7 69.7 0.00023 21.7 1.5 11.2 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS75723.1 - 3.5e-22 77.8 79.5 1.1e-06 28.7 0.6 12.3 12 1 0 12 12 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS75723.1 - 5e-11 42.6 46.2 0.11 12.8 4.0 10.4 9 1 1 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS75723.1 - 8.4e-10 38.7 44.7 0.13 12.7 0.3 9.9 9 0 0 9 9 9 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS75723.1 - 1.4e-06 28.1 69.0 0.32 11.1 0.1 11.3 11 1 0 11 11 11 6 C2H2-type zinc finger SUIM_assoc PF16619.5 RUS75723.1 - 0.00018 21.5 1.6 0.00018 21.5 1.6 4.0 4 0 0 4 4 3 1 Unstructured region C-term to UIM in Ataxin3 zf-Di19 PF05605.12 RUS75723.1 - 0.001 19.3 9.8 0.005 17.1 1.1 8.0 5 1 4 9 9 9 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS75723.1 - 1.5 9.5 36.7 5.1 7.8 0.2 7.3 3 2 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats DUF4805 PF16063.5 RUS75723.1 - 2 7.7 9.4 1.2 8.4 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) zf-C2H2_11 PF16622.5 RUS75723.1 - 2.2 8.1 20.5 6.4 6.6 0.1 6.6 7 0 0 7 7 7 0 zinc-finger C2H2-type DUF2367 PF10164.9 RUS75723.1 - 5.5 7.5 6.8 19 5.8 5.4 2.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Suf PF05843.14 RUS75723.1 - 5.9 6.8 7.7 14 5.6 7.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UBZ_FAAP20 PF15750.5 RUS75723.1 - 7.2 6.6 13.6 2.3 8.2 0.7 5.3 5 0 0 5 5 5 0 Ubiquitin-binding zinc-finger Zn-C2H2_12 PF18112.1 RUS75723.1 - 7.8 7.1 25.9 2.2 8.8 0.2 6.8 8 0 0 8 8 7 0 Autophagy receptor zinc finger-C2H2 domain CN_hydrolase PF00795.22 RUS75724.1 - 3.5e-66 223.2 0.0 4.1e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FtsX PF02687.21 RUS75725.1 - 0.0022 18.4 0.1 0.003 18.0 0.1 1.2 1 0 0 1 1 1 1 FtsX-like permease family Sacchrp_dh_NADP PF03435.18 RUS75726.1 - 2.9e-18 66.4 0.0 4.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TatD_DNase PF01026.21 RUS75726.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase Sacchrp_dh_NADP PF03435.18 RUS75727.1 - 4.4e-21 75.5 0.0 6.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 RUS75727.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Fibrinogen_C PF00147.18 RUS75728.1 - 0.00015 21.6 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain XhlA PF10779.9 RUS75728.1 - 0.0046 17.1 7.7 0.039 14.2 3.5 2.2 1 1 1 2 2 2 1 Haemolysin XhlA Fzo_mitofusin PF04799.13 RUS75728.1 - 0.0052 16.4 0.2 0.0088 15.6 0.2 1.3 1 0 0 1 1 1 1 fzo-like conserved region RPW8 PF05659.11 RUS75728.1 - 0.019 14.7 4.0 0.13 12.0 3.2 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TBCC_N PF16752.5 RUS75728.1 - 0.022 15.2 0.9 0.22 12.0 0.9 2.0 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain NPV_P10 PF05531.12 RUS75728.1 - 0.047 14.1 2.8 0.26 11.8 2.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC53 PF10152.9 RUS75728.1 - 0.063 13.7 2.5 3.5 8.0 0.2 2.1 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex BLOC1_2 PF10046.9 RUS75728.1 - 0.12 12.7 1.3 0.19 12.0 0.5 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CMV_1a_C PF12503.8 RUS75728.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein C terminal SlyX PF04102.12 RUS75728.1 - 0.16 12.6 4.6 0.25 12.0 0.3 2.4 1 1 1 2 2 2 0 SlyX DUF1712 PF08217.11 RUS75728.1 - 0.16 10.4 1.3 0.2 10.1 1.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Matrilin_ccoil PF10393.9 RUS75728.1 - 1.5 8.8 3.5 2.3 8.2 0.2 2.5 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin SesA PF17107.5 RUS75730.1 - 0.0074 16.5 2.2 0.013 15.7 1.4 1.8 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases BshC PF10079.9 RUS75730.1 - 0.025 13.4 1.5 0.033 12.9 1.5 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DASH_Duo1 PF08651.10 RUS75730.1 - 0.034 13.9 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 Eco57I PF07669.11 RUS75730.1 - 0.042 14.3 0.1 0.072 13.6 0.1 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase PhaP_Bmeg PF09602.10 RUS75730.1 - 0.052 13.5 1.3 0.08 12.9 1.3 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Gp-FAR-1 PF05823.12 RUS75730.1 - 0.071 13.5 5.3 0.11 12.8 5.0 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AIM3 PF17096.5 RUS75730.1 - 0.37 11.7 2.1 2.2 9.3 0.5 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF948 PF06103.11 RUS75730.1 - 0.41 10.9 5.4 18 5.7 0.1 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MT0933_antitox PF14013.6 RUS75730.1 - 2.1 8.7 12.2 8.6 6.8 2.4 3.4 2 1 1 3 3 3 0 MT0933-like antitoxin protein A_deaminase PF00962.22 RUS75731.1 - 6.8e-118 393.7 0.9 2.8e-117 391.7 0.3 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase DUF1633 PF07794.11 RUS75733.1 - 0.028 12.6 0.4 0.033 12.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) HLH PF00010.26 RUS75734.1 - 9.5e-06 25.5 1.4 9.5e-06 25.5 1.4 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1700 PF08006.11 RUS75735.1 - 0.00055 19.5 0.2 0.0012 18.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) Utp14 PF04615.13 RUS75736.1 - 2.2 6.8 29.6 3.6 6.0 29.6 1.2 1 0 0 1 1 1 0 Utp14 protein Herpes_IR6 PF06307.12 RUS75738.1 - 0.083 12.4 0.4 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus IR6 protein E1_DerP2_DerF2 PF02221.15 RUS75739.1 - 1.1e-22 80.9 1.9 1.2e-22 80.7 1.9 1.1 1 0 0 1 1 1 1 ML domain BSMAP PF12280.8 RUS75741.1 - 0.026 14.7 0.1 0.027 14.7 0.1 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein E1_DerP2_DerF2 PF02221.15 RUS75742.1 - 1.5e-24 86.9 4.3 2.1e-24 86.5 4.3 1.2 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 RUS75743.1 - 3.6e-22 79.2 2.2 4.1e-22 79.0 2.2 1.0 1 0 0 1 1 1 1 ML domain Gp138_N PF18352.1 RUS75743.1 - 0.043 13.9 0.1 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 Phage protein Gp138 N-terminal domain WD40 PF00400.32 RUS75744.1 - 2.9e-08 34.2 2.3 0.47 11.4 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75744.1 - 0.0026 18.0 0.0 0.069 13.5 0.0 2.3 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RUS75744.1 - 0.069 13.2 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Myosin-VI_CBD PF16521.5 RUS75744.1 - 0.11 12.6 0.0 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Myosin VI cargo binding domain MOZ_SAS PF01853.18 RUS75745.1 - 4.2e-81 270.9 0.1 6.1e-81 270.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RUS75745.1 - 1.4e-25 88.7 4.9 3.6e-25 87.3 4.9 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 RUS75745.1 - 3.6e-20 71.6 0.2 7.5e-20 70.6 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 RUS75745.1 - 0.00064 19.6 2.0 0.0077 16.1 0.1 3.0 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_7 PF13508.7 RUS75745.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RGS PF00615.19 RUS75746.1 - 2e-27 95.8 5.4 5.1e-07 30.0 0.0 4.8 4 0 0 4 4 4 4 Regulator of G protein signaling domain TetR_C_11 PF16859.5 RUS75746.1 - 0.6 10.4 3.9 2 8.8 3.9 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 RUS75747.1 - 1.4e-37 127.0 30.1 2e-06 28.4 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS75747.1 - 8.5e-09 35.6 10.0 0.62 10.4 0.3 6.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS75747.1 - 5.5e-07 29.2 2.1 0.0014 18.0 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 RUS75747.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 RUS75747.1 - 6.6e-05 21.7 6.1 0.09 11.4 0.2 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.33 RUS75747.1 - 0.00037 20.3 0.1 0.00094 19.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain CXCXC PF03128.14 RUS75747.1 - 0.041 14.3 0.7 0.041 14.3 0.7 3.1 2 0 0 2 2 2 0 CXCXC repeat PQQ_2 PF13360.6 RUS75747.1 - 0.05 13.2 0.1 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Cyclin_N PF00134.23 RUS75748.1 - 1.9e-16 60.0 0.0 2.4e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS75748.1 - 0.00015 21.8 0.3 0.00041 20.4 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2457 PF10446.9 RUS75748.1 - 0.92 8.6 6.4 1.7 7.7 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rubis-subs-bind PF09273.11 RUS75749.1 - 4.3e-23 82.4 0.1 1.1e-22 81.1 0.0 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 RUS75749.1 - 6.6e-12 46.1 0.0 1.5e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 SET domain 7tm_3 PF00003.22 RUS75750.1 - 6.5e-41 140.6 22.9 9.4e-41 140.1 22.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR dCache_1 PF02743.18 RUS75750.1 - 0.012 15.4 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Cache domain DUF4131 PF13567.6 RUS75750.1 - 2.8 7.6 10.2 3.8 7.1 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) RabGAP-TBC PF00566.18 RUS75751.1 - 2.6e-24 86.1 0.4 2.8e-24 86.0 0.4 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Laminin_II PF06009.12 RUS75752.1 - 6.3e-10 39.2 7.4 0.00021 21.3 1.8 2.4 1 1 1 2 2 2 2 Laminin Domain II MSP1b PF03429.13 RUS75752.1 - 2.3e-08 32.7 9.3 0.00012 20.3 3.1 3.2 1 1 1 2 2 2 2 Major surface protein 1B WXG100 PF06013.12 RUS75752.1 - 5.9e-08 32.8 7.4 0.00012 22.2 2.1 2.9 1 1 1 2 2 2 2 Proteins of 100 residues with WXG MCPsignal PF00015.21 RUS75752.1 - 3.4e-07 30.3 9.5 0.00016 21.5 3.9 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 RUS75752.1 - 7.1e-07 29.4 26.4 0.018 15.4 9.3 3.2 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 RUS75752.1 - 2.6e-06 27.3 31.6 3e-05 23.8 31.6 2.4 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein EzrA PF06160.12 RUS75752.1 - 3.6e-06 25.5 31.0 1.4e-05 23.5 31.0 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.6 RUS75752.1 - 5.2e-06 25.9 13.5 0.025 13.9 2.7 2.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 RUS75752.1 - 6.8e-06 25.3 29.4 0.0052 15.8 15.3 2.3 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Sec34 PF04136.15 RUS75752.1 - 1.1e-05 25.3 18.6 0.068 13.0 3.2 2.9 1 1 1 2 2 2 2 Sec34-like family DUF1664 PF07889.12 RUS75752.1 - 3.1e-05 24.0 8.1 0.011 15.8 1.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) FapA PF03961.13 RUS75752.1 - 5.3e-05 22.0 21.8 0.0065 15.1 9.0 2.0 1 1 1 2 2 2 2 Flagellar Assembly Protein A DUF4744 PF15918.5 RUS75752.1 - 7.6e-05 23.5 30.6 1.7 9.6 8.8 3.9 1 1 3 4 4 4 2 Domain of unknown function (DUF4744) DUF4041 PF13250.6 RUS75752.1 - 7.6e-05 22.5 21.4 1.8 8.5 0.6 5.7 1 1 2 3 3 2 1 Domain of unknown function (DUF4041) Spc7 PF08317.11 RUS75752.1 - 7.9e-05 21.7 8.4 0.0026 16.7 4.1 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF3552 PF12072.8 RUS75752.1 - 9.8e-05 21.9 3.6 0.069 12.6 0.4 2.6 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) DUF948 PF06103.11 RUS75752.1 - 0.00013 22.1 0.0 1 9.7 0.0 2.8 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 RUS75752.1 - 0.0002 21.1 7.8 0.056 13.2 2.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF745) COG6 PF06419.11 RUS75752.1 - 0.00037 18.8 10.9 0.034 12.4 1.7 2.6 1 1 0 2 2 2 2 Conserved oligomeric complex COG6 DUF5344 PF17279.2 RUS75752.1 - 0.00053 20.5 32.0 48 4.6 10.2 6.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) Syntaxin PF00804.25 RUS75752.1 - 0.00058 19.6 11.2 0.067 12.9 3.8 2.2 1 1 1 2 2 2 2 Syntaxin APG17 PF04108.12 RUS75752.1 - 0.00068 18.9 16.9 3.5 6.7 16.9 3.0 1 1 0 1 1 1 0 Autophagy protein Apg17 Sam68-YY PF16568.5 RUS75752.1 - 0.00076 20.2 49.8 84 4.0 8.2 7.3 1 1 1 2 2 1 0 Tyrosine-rich domain of Sam68 DUF812 PF05667.11 RUS75752.1 - 0.0019 17.1 12.8 0.0022 16.9 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) THOC7 PF05615.13 RUS75752.1 - 0.0033 17.7 9.2 0.014 15.7 2.6 2.1 1 1 1 2 2 2 2 Tho complex subunit 7 Acetyltransf_11 PF13720.6 RUS75752.1 - 0.0037 17.7 11.8 8e+02 0.6 11.8 3.8 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 KELK PF15796.5 RUS75752.1 - 0.0042 17.5 3.8 0.85 10.1 0.5 2.3 1 1 1 2 2 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase GCN5L1 PF06320.13 RUS75752.1 - 0.0046 17.1 7.8 3.5 7.8 7.8 2.6 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF4047 PF13256.6 RUS75752.1 - 0.0063 16.7 25.1 2.8e+02 1.7 25.1 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) HemX PF04375.14 RUS75752.1 - 0.0068 15.7 15.1 0.16 11.3 4.9 2.1 1 1 1 2 2 2 2 HemX, putative uroporphyrinogen-III C-methyltransferase FH2 PF02181.23 RUS75752.1 - 0.0091 15.2 8.4 0.19 10.8 8.4 2.0 1 1 0 1 1 1 1 Formin Homology 2 Domain SOAR PF16533.5 RUS75752.1 - 0.011 15.7 4.3 7.2 6.7 0.3 3.3 1 1 2 3 3 3 0 STIM1 Orai1-activating region TMPIT PF07851.13 RUS75752.1 - 0.011 15.0 22.7 0.24 10.6 9.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein FPP PF05911.11 RUS75752.1 - 0.014 13.7 12.3 0.016 13.4 12.3 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4200 PF13863.6 RUS75752.1 - 0.021 15.2 8.9 0.24 11.8 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CHDCT2 PF08074.11 RUS75752.1 - 0.021 15.0 9.1 0.14 12.3 4.4 2.2 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain DUF16 PF01519.16 RUS75752.1 - 0.021 15.3 12.5 0.53 10.8 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 RmuC PF02646.16 RUS75752.1 - 0.024 13.8 11.9 1.3e+02 1.5 11.9 2.9 1 1 0 1 1 1 0 RmuC family Complex1_49kDa PF00346.19 RUS75752.1 - 0.026 13.6 10.5 0.3 10.1 2.1 2.4 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF2385 PF09539.10 RUS75752.1 - 0.027 15.0 16.6 19 5.9 2.0 5.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2385) Lebercilin PF15619.6 RUS75752.1 - 0.036 13.7 3.3 0.046 13.4 3.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin PF02996.17 RUS75752.1 - 0.045 13.7 14.3 13 5.8 3.4 3.6 1 1 1 2 2 2 0 Prefoldin subunit DUF211 PF02680.14 RUS75752.1 - 0.047 13.8 2.2 11 6.3 0.3 3.1 1 1 2 3 3 3 0 Uncharacterized ArCR, COG1888 Tropomyosin_1 PF12718.7 RUS75752.1 - 0.05 13.8 4.0 0.25 11.5 4.0 2.2 1 1 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 RUS75752.1 - 0.053 13.9 0.0 32 5.0 0.0 2.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ferritin-like PF12902.7 RUS75752.1 - 0.056 13.3 14.8 1.3e+02 2.3 14.8 3.1 1 1 0 1 1 1 0 Ferritin-like BRE1 PF08647.11 RUS75752.1 - 0.056 13.5 18.4 2.8 8.1 10.6 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TssC PF17541.2 RUS75752.1 - 0.084 11.7 18.5 0.76 8.5 3.6 3.0 1 1 2 3 3 3 0 Type VI secretion system, TssC, VipB DASH_Duo1 PF08651.10 RUS75752.1 - 0.091 12.6 11.3 2.7e+03 -1.8 11.3 4.0 1 1 0 1 1 0 0 DASH complex subunit Duo1 Lge1 PF11488.8 RUS75752.1 - 0.098 12.9 33.4 1.8e+04 -17.9 33.4 5.3 1 1 0 1 1 0 0 Transcriptional regulatory protein LGE1 Uso1_p115_C PF04871.13 RUS75752.1 - 0.12 12.8 15.3 0.96 9.8 5.0 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.20 RUS75752.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Tropomyosin DUF2959 PF11172.8 RUS75752.1 - 0.13 12.4 17.9 4.1 7.5 11.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Rogdi_lz PF10259.9 RUS75752.1 - 0.16 11.4 5.0 8.8 5.7 5.0 2.3 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein OEP PF02321.18 RUS75752.1 - 0.16 11.7 20.2 3.7e+02 0.8 20.2 3.3 1 1 0 1 1 1 0 Outer membrane efflux protein DUF4665 PF15679.5 RUS75752.1 - 0.22 12.2 13.4 1e+03 0.4 13.4 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) Fib_alpha PF08702.10 RUS75752.1 - 0.22 11.7 28.9 5.2e+03 -2.5 28.9 2.8 1 1 0 1 1 0 0 Fibrinogen alpha/beta chain family DUF2232 PF09991.9 RUS75752.1 - 0.33 10.1 15.4 2.2 7.4 1.8 3.1 1 1 2 3 3 3 0 Predicted membrane protein (DUF2232) DUF4795 PF16043.5 RUS75752.1 - 0.41 10.2 14.1 1.1e+02 2.3 14.1 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SKA1 PF07160.12 RUS75752.1 - 0.42 10.4 15.5 1.7 8.4 1.3 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Exonuc_VII_L PF02601.15 RUS75752.1 - 0.6 9.6 12.7 1.4 8.4 12.7 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit ISG65-75 PF11727.8 RUS75752.1 - 0.64 9.2 13.8 2.7 7.1 5.9 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein SPACA9 PF15120.6 RUS75752.1 - 0.77 9.5 17.3 15 5.3 2.1 4.8 1 1 1 2 2 1 0 Sperm acrosome-associated protein 9 DUF2009 PF09418.10 RUS75752.1 - 0.85 8.6 23.1 2.6 7.0 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) DUF3450 PF11932.8 RUS75752.1 - 0.94 8.7 20.9 0.53 9.5 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 RUS75752.1 - 0.94 9.7 9.0 28 4.9 9.0 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 RUS75752.1 - 1.1 10.1 27.7 1.8e+04 -6.7 27.7 2.8 1 1 0 1 1 0 0 Occludin homology domain CREPT PF16566.5 RUS75752.1 - 1.2 9.3 11.9 2.3 8.4 3.6 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PI_PP_I PF18363.1 RUS75752.1 - 1.3 9.3 12.5 7.4e+02 0.4 12.5 2.6 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain PI3K_P85_iSH2 PF16454.5 RUS75752.1 - 1.9 8.1 32.0 13 5.3 4.7 4.1 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Y_phosphatase3 PF13350.6 RUS75752.1 - 3.2 7.7 6.7 73 3.2 6.6 2.6 1 1 0 1 1 1 0 Tyrosine phosphatase family ApoO PF09769.9 RUS75752.1 - 4.5 7.2 16.7 1.8e+04 -5.7 16.7 3.4 1 1 0 1 1 0 0 Apolipoprotein O Cortex-I_coil PF09304.10 RUS75752.1 - 4.6 7.5 7.9 2.9e+02 1.7 7.9 2.4 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF724 PF05266.14 RUS75752.1 - 5 6.9 10.9 80 3.0 10.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) AI-2E_transport PF01594.16 RUS75752.1 - 5.3 6.1 17.4 6.5e+03 -4.1 17.4 2.7 1 1 0 1 1 0 0 AI-2E family transporter FliD_C PF07195.12 RUS75752.1 - 5.5 6.3 29.7 14 5.0 8.4 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Sec8_exocyst PF04048.14 RUS75752.1 - 10 6.0 28.8 1.7e+04 -4.5 28.8 2.4 1 1 0 1 1 0 0 Sec8 exocyst complex component specific domain GNT-I PF03071.15 RUS75753.1 - 9.6e-127 423.3 1.5 1.1e-126 423.2 1.5 1.0 1 0 0 1 1 1 1 GNT-I family Ribosomal_60s PF00428.19 RUS75755.1 - 8.1 7.1 10.5 2 9.0 0.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAXX PF15384.6 RUS75757.1 - 9.9e-05 22.1 2.0 0.27 10.9 0.1 3.5 1 1 2 3 3 3 3 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 PdxJ PF03740.13 RUS75757.1 - 0.011 14.8 5.6 10 5.1 0.5 4.1 1 1 2 3 3 3 0 Pyridoxal phosphate biosynthesis protein PdxJ FAM176 PF14851.6 RUS75758.1 - 0.0043 16.7 3.2 0.1 12.3 0.1 2.1 2 0 0 2 2 2 2 FAM176 family Laminin_EGF PF00053.24 RUS75759.1 - 8e-06 25.9 48.6 2.2 8.5 15.2 4.7 1 1 3 4 4 4 3 Laminin EGF domain TIL PF01826.17 RUS75759.1 - 3.2e-05 24.1 37.7 0.041 14.1 7.1 3.5 1 1 2 3 3 3 3 Trypsin Inhibitor like cysteine rich domain DEFB136 PF17333.2 RUS75759.1 - 0.00022 21.1 11.2 0.2 11.7 2.3 3.5 3 0 0 3 3 3 3 Beta defensin 136 DSL PF01414.19 RUS75759.1 - 0.0016 18.6 47.5 0.068 13.4 8.9 4.2 2 1 2 4 4 4 3 Delta serrate ligand NPR3 PF03666.13 RUS75759.1 - 0.81 8.4 6.1 1 8.1 6.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 RUS75759.1 - 7.5 5.2 9.2 9.3 4.9 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.9 RUS75760.1 - 0.032 13.4 33.7 0.045 12.9 33.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS75760.1 - 0.033 12.4 17.9 0.053 11.7 17.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 RUS75760.1 - 0.036 12.1 2.3 0.065 11.3 2.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen S100PBPR PF15427.6 RUS75760.1 - 0.12 11.7 5.0 0.19 10.9 5.0 1.3 1 0 0 1 1 1 0 S100P-binding protein Mpp10 PF04006.12 RUS75760.1 - 0.32 9.4 11.2 0.43 9.0 11.2 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RUS75760.1 - 0.95 7.7 18.8 1.3 7.2 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RUS75760.1 - 1.2 8.3 9.5 1.8 7.7 9.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RUS75760.1 - 1.9 6.5 33.9 2.7 6.0 33.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RUS75760.1 - 4 6.7 15.9 5.9 6.2 15.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pes-10 PF07149.11 RUS75760.1 - 7.3 5.5 17.7 11 5.0 17.7 1.1 1 0 0 1 1 1 0 Pes-10 Nop25 PF09805.9 RUS75760.1 - 9.5 6.7 8.8 15 6.1 8.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) KH_1 PF00013.29 RUS75761.1 - 0.047 13.5 0.1 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 KH domain TIL PF01826.17 RUS75761.1 - 0.75 10.1 27.1 8.5 6.7 10.8 2.3 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Toxin_22 PF08092.11 RUS75761.1 - 3.8 7.6 18.0 3.1 7.9 2.8 3.7 2 2 1 3 3 3 0 Magi peptide toxin family Ldl_recept_a PF00057.18 RUS75762.1 - 1.8e-122 399.2 292.4 1.1e-11 44.7 7.7 15.8 15 1 0 15 15 15 14 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 RUS75762.1 - 4.9e-28 97.3 2.8 7e-10 39.2 0.0 5.9 6 1 0 6 6 6 4 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 RUS75762.1 - 2.7e-23 81.5 35.9 2.6e-10 40.0 1.5 7.5 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS75762.1 - 3.4e-17 62.4 38.9 6.2e-09 35.9 7.8 18.5 7 3 6 13 13 13 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS75762.1 - 4.6e-13 49.2 42.2 6.9e-07 29.4 6.1 9.6 10 1 0 10 10 10 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS75762.1 - 9.6e-05 22.6 2.1 9.6e-05 22.6 2.1 15.7 16 1 0 16 16 16 4 EGF-like domain hEGF PF12661.7 RUS75762.1 - 0.0039 17.8 2.5 0.0039 17.8 2.5 16.9 18 3 1 19 19 19 2 Human growth factor-like EGF SGL PF08450.12 RUS75762.1 - 0.006 16.2 0.1 0.04 13.5 0.0 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 RUS75762.1 - 0.2 11.9 0.0 53 4.1 0.0 3.3 3 0 0 3 3 3 0 Arylesterase Lectin_C PF00059.21 RUS75763.1 - 1.4e-44 151.2 13.6 8.6e-14 52.2 0.3 4.7 4 0 0 4 4 4 4 Lectin C-type domain PAN_1 PF00024.26 RUS75763.1 - 4.6e-16 58.6 15.2 0.0038 17.2 0.2 4.9 4 0 0 4 4 4 4 PAN domain CDC45 PF02724.14 RUS75763.1 - 1.6e-05 23.5 13.3 2.4e-05 22.9 13.3 1.1 1 0 0 1 1 1 1 CDC45-like protein PAN_4 PF14295.6 RUS75763.1 - 0.00011 22.1 26.3 1.2 9.1 1.1 5.2 4 0 0 4 4 4 4 PAN domain Peptidase_M4_C PF02868.15 RUS75763.1 - 0.084 12.7 0.0 44 3.9 0.0 3.5 3 0 0 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain PPP4R2 PF09184.11 RUS75763.1 - 0.57 9.7 17.6 1.1 8.7 17.6 1.4 1 0 0 1 1 1 0 PPP4R2 DUF4893 PF16233.5 RUS75763.1 - 1.5 8.4 9.7 31 4.1 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4893) SAPS PF04499.15 RUS75763.1 - 1.6 7.4 5.2 2.2 7.0 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS75763.1 - 3.2 5.8 33.1 4.5 5.4 33.1 1.0 1 0 0 1 1 1 0 Nop14-like family 7TM_GPCR_Srx PF10328.9 RUS75764.1 - 7.4e-07 29.1 6.1 8.5e-07 28.9 6.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS75764.1 - 8e-05 22.1 3.3 9.4e-05 21.9 3.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS75764.1 - 0.013 15.5 1.2 0.025 14.6 1.2 1.6 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_4 PF13853.6 RUS75764.1 - 0.014 15.2 1.9 0.018 14.8 1.9 1.3 1 1 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srv PF10323.9 RUS75764.1 - 0.073 12.4 3.2 0.12 11.7 3.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 RUS75765.1 - 2.1e-06 27.2 0.4 0.0052 16.1 0.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS75765.1 - 0.11 11.8 1.9 0.31 10.3 1.9 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SelP_N PF04592.14 RUS75765.1 - 0.13 11.6 14.0 0.22 10.9 14.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PKD_channel PF08016.12 RUS75766.1 - 1.4e-21 76.7 22.3 1.6e-21 76.5 22.3 1.0 1 0 0 1 1 1 1 Polycystin cation channel Sec61_beta PF03911.16 RUS75770.1 - 4.9e-22 77.7 0.2 7.2e-22 77.1 0.2 1.3 1 0 0 1 1 1 1 Sec61beta family AAA_30 PF13604.6 RUS75772.1 - 5.7e-24 84.9 0.1 1e-17 64.5 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.6 RUS75772.1 - 3e-12 47.1 0.3 5.9e-07 29.9 0.0 3.7 4 1 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 RUS75772.1 - 7.5e-10 38.9 5.0 0.012 15.4 0.3 5.0 4 1 1 5 5 5 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 RUS75772.1 - 5.3e-06 26.2 0.7 1.3e-05 25.0 0.7 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 RUS75772.1 - 0.00014 22.2 0.5 0.76 10.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 RUS75772.1 - 0.00029 21.3 1.5 0.014 15.8 0.1 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 RUS75772.1 - 0.0036 17.1 0.1 0.017 14.9 0.0 5.4 5 1 0 5 5 4 2 AAA domain PIF1 PF05970.14 RUS75772.1 - 0.0048 16.1 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase CbiA PF01656.23 RUS75772.1 - 0.0061 16.6 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 RUS75772.1 - 0.03 13.5 0.1 0.58 9.3 0.1 2.5 2 0 0 2 2 2 0 Anion-transporting ATPase PRK PF00485.18 RUS75772.1 - 0.041 13.6 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 RUS75772.1 - 0.043 13.7 2.2 0.045 13.7 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ParA PF10609.9 RUS75772.1 - 0.061 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DEAD PF00270.29 RUS75772.1 - 0.067 12.9 1.8 1 9.1 0.5 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 RUS75772.1 - 0.082 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 RUS75772.1 - 0.11 12.8 0.5 24 5.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RUS75772.1 - 0.11 12.6 0.1 0.52 10.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 RUS75772.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.3 4 0 0 4 4 4 0 ABC transporter AAA_18 PF13238.6 RUS75772.1 - 2.8 8.5 5.2 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain dCache_1 PF02743.18 RUS75773.1 - 0.02 14.7 0.9 78 2.9 0.1 4.9 1 1 2 3 3 3 0 Cache domain AIG1 PF04548.16 RUS75775.1 - 2e-39 135.1 0.1 2e-39 135.1 0.1 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS75775.1 - 1.6e-07 31.4 0.1 1.6e-07 31.4 0.1 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS75775.1 - 0.0003 20.3 0.1 0.00064 19.3 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Fib_alpha PF08702.10 RUS75775.1 - 0.25 11.5 9.1 0.066 13.4 5.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 RUS75775.1 - 1.4 9.2 12.6 2.2 8.5 12.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein WDCP PF15390.6 RUS75775.1 - 1.5 7.1 9.1 1.9 6.8 9.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Dynamin_N PF00350.23 RUS75775.1 - 2 8.5 18.8 6.5 6.8 1.7 4.2 3 1 1 4 4 4 0 Dynamin family DUF4404 PF14357.6 RUS75775.1 - 2.5 8.8 9.4 0.5 11.0 3.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) CemA PF03040.14 RUS75775.1 - 2.6 7.9 6.2 4.4 7.2 6.2 1.3 1 0 0 1 1 1 0 CemA family Jnk-SapK_ap_N PF09744.9 RUS75775.1 - 5 7.3 23.2 0.21 11.8 14.8 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 AIG1 PF04548.16 RUS75776.1 - 5.5e-23 81.4 0.0 1.2e-22 80.3 0.0 1.5 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 RUS75776.1 - 5.3e-06 26.6 0.1 0.18 11.9 0.2 2.8 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 RUS75776.1 - 0.00018 21.6 0.0 0.00044 20.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_8 PF13855.6 RUS75777.1 - 8.5e-111 361.7 103.8 6.8e-15 54.6 2.4 10.2 4 4 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 RUS75777.1 - 1.1e-43 146.4 68.7 2.6e-08 34.0 1.8 12.4 8 3 4 13 13 13 12 Leucine Rich repeats (2 copies) EGF PF00008.27 RUS75777.1 - 4.1e-41 138.9 102.0 1.4e-08 34.8 6.8 9.3 8 0 0 8 8 7 7 EGF-like domain LRR_5 PF13306.6 RUS75777.1 - 2.9e-39 133.9 8.3 4.3e-09 36.4 0.0 5.0 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS75777.1 - 9.5e-22 77.3 30.1 1.8e-07 30.8 0.3 6.0 4 3 2 6 6 6 6 Leucine-rich repeat Laminin_G_1 PF00054.23 RUS75777.1 - 1.3e-21 77.1 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRRNT PF01462.18 RUS75777.1 - 5.9e-20 70.5 48.0 8.4e-10 38.1 3.6 7.2 8 0 0 8 8 8 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.24 RUS75777.1 - 2.3e-18 67.0 0.0 4.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 RUS75777.1 - 2.7e-16 59.5 110.4 1.7e-05 25.3 3.7 11.7 12 1 0 12 12 10 6 Human growth factor-like EGF LRRCT PF01463.24 RUS75777.1 - 8.9e-12 44.6 8.2 0.16 12.6 0.1 6.1 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 RUS75777.1 - 6.4e-10 38.2 52.8 0.33 11.7 0.0 16.9 19 2 0 19 19 17 6 Leucine Rich Repeat EGF_CA PF07645.15 RUS75777.1 - 6.4 7.1 127.7 0.022 14.9 12.1 9.7 6 2 3 9 9 7 0 Calcium-binding EGF domain HEM4 PF02602.15 RUS75778.1 - 3.6e-09 36.3 0.0 4.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HEM4 PF02602.15 RUS75779.1 - 6.5e-29 100.9 0.0 7.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD MADF_DNA_bdg PF10545.9 RUS75780.1 - 4.7e-13 49.3 1.8 8.2e-13 48.5 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS75780.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 BESS motif NolB PF17398.2 RUS75780.1 - 0.0027 18.1 0.1 0.0041 17.5 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein NolB NKWYS PF10364.9 RUS75781.1 - 0.067 13.3 1.8 2.5 8.2 0.1 2.1 1 1 1 2 2 2 0 Putative capsular polysaccharide synthesis protein Ste5 PF11610.8 RUS75781.1 - 0.21 11.5 1.5 4.2 7.3 0.2 2.8 3 0 0 3 3 3 0 Scaffold protein Ste5, Fus3-binding region DUF5641 PF18701.1 RUS75782.1 - 5.2e-22 77.8 0.8 1e-21 76.8 0.8 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1758 PF05585.12 RUS75782.1 - 2.2e-12 47.1 0.0 4.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 RUS75782.1 - 2.5e-07 31.3 0.0 5.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS75782.1 - 2.8e-06 27.8 0.0 7.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 RUS75782.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 RUS75782.1 - 0.17 11.7 0.3 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease eIF3g PF12353.8 RUS75782.1 - 7 7.1 7.4 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Sugar_tr PF00083.24 RUS75784.1 - 1.9e-19 69.9 0.3 3.5e-19 69.0 0.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS75784.1 - 3.1e-06 26.4 8.0 3.1e-06 26.4 8.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Filamin PF00630.19 RUS75785.1 - 8.9e-37 126.0 0.0 3.7e-14 53.4 0.0 3.3 3 0 0 3 3 3 3 Filamin/ABP280 repeat Filamin PF00630.19 RUS75786.1 - 4.4e-98 323.0 13.6 1.1e-14 55.0 0.2 10.2 10 0 0 10 10 10 10 Filamin/ABP280 repeat CH PF00307.31 RUS75786.1 - 7.4e-13 48.6 0.0 8.3e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF5060 PF16586.5 RUS75786.1 - 1.4e-08 35.0 0.6 0.81 10.1 0.0 7.1 9 1 0 9 9 9 2 Domain of unknown function (DUF5060) Big_3_5 PF16640.5 RUS75786.1 - 1.7e-05 24.9 5.3 2.1 8.6 0.0 5.9 7 0 0 7 7 7 1 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.13 RUS75786.1 - 2.3e-05 24.3 0.3 0.42 10.6 0.1 5.3 7 0 0 7 7 7 1 Y_Y_Y domain Big_6 PF17936.1 RUS75786.1 - 0.0059 16.9 0.3 15 5.9 0.0 4.8 3 1 1 4 4 4 1 Bacterial Ig domain CAMSAP_CH PF11971.8 RUS75786.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain BiPBP_C PF06832.12 RUS75786.1 - 0.018 15.1 0.0 0.64 10.1 0.0 3.6 4 0 0 4 4 4 0 Penicillin-Binding Protein C-terminus Family CBM_6 PF03422.15 RUS75786.1 - 0.11 12.8 1.1 29 5.0 0.0 4.7 6 0 0 6 6 6 0 Carbohydrate binding module (family 6) PKD PF00801.20 RUS75786.1 - 6.9 6.6 8.2 55 3.7 0.1 4.6 5 0 0 5 5 5 0 PKD domain CH PF00307.31 RUS75788.1 - 5.6e-27 94.1 0.4 3.4e-24 85.1 0.1 2.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS75788.1 - 0.00057 19.7 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain DUF3422 PF11902.8 RUS75788.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) G8 PF10162.9 RUS75790.1 - 3.8e-22 78.6 0.1 4.7e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.6 RUS75790.1 - 0.043 12.6 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless ILEI PF15711.5 RUS75791.1 - 1.4e-08 35.1 0.0 8.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Interleukin-like EMT inducer Beta_helix PF13229.6 RUS75791.1 - 2.5e-07 30.7 1.8 2.5e-07 30.7 1.8 3.6 3 1 0 3 3 3 1 Right handed beta helix region NosD PF05048.13 RUS75791.1 - 0.00018 20.9 4.5 0.00025 20.4 3.2 1.9 2 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) G8 PF10162.9 RUS75791.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 G8 domain G8 PF10162.9 RUS75792.1 - 1.9e-30 105.5 0.1 3.6e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 G8 domain ILEI PF15711.5 RUS75792.1 - 1.4e-07 31.9 0.0 6.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Interleukin-like EMT inducer Beta_helix PF13229.6 RUS75792.1 - 1.1e-06 28.6 7.3 1.5e-05 24.9 0.2 3.8 3 1 0 4 4 4 2 Right handed beta helix region NosD PF05048.13 RUS75792.1 - 0.00096 18.5 2.4 0.039 13.2 2.6 2.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 RUS75794.1 - 3.8e-07 30.1 6.1 0.00014 21.8 6.0 2.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 RUS75794.1 - 3.7e-06 26.4 0.2 0.001 18.4 0.0 2.3 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) G8 PF10162.9 RUS75795.1 - 7.6e-18 64.8 0.0 1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 G8 domain ILEI PF15711.5 RUS75795.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Interleukin-like EMT inducer G8 PF10162.9 RUS75796.1 - 1.2e-21 77.1 0.0 1.4e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.6 RUS75796.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Alpha_L_fucos PF01120.17 RUS75797.1 - 9.8e-121 403.5 10.1 1.2e-120 403.2 10.1 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 RUS75797.1 - 9.2e-25 87.0 0.0 1.7e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 RUS75797.1 - 0.039 14.0 0.2 0.12 12.5 0.2 1.9 1 1 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator DUF3270 PF11674.8 RUS75798.1 - 0.0039 17.3 0.4 0.0067 16.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) BacteriocIIc_cy PF12173.8 RUS75798.1 - 0.11 12.7 0.2 1.9 8.8 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like DUF948 PF06103.11 RUS75799.1 - 0.0016 18.7 0.0 0.052 13.8 0.0 2.6 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 RUS75799.1 - 0.013 15.3 2.9 0.19 11.6 0.5 2.6 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1421 PF07223.11 RUS75799.1 - 0.044 13.6 0.0 75 3.3 0.0 3.7 2 2 3 5 5 5 0 UBA-like domain (DUF1421) DUF4208 PF13907.6 RUS75799.1 - 0.045 14.2 0.9 3 8.4 0.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4208) DUF16 PF01519.16 RUS75799.1 - 0.082 13.4 0.0 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Pkinase PF00069.25 RUS75800.1 - 8.3e-40 136.8 0.1 9.9e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75800.1 - 3.5e-14 52.7 0.0 4.3e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS75800.1 - 0.032 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RUS75800.1 - 0.034 14.1 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_14 PF13428.6 RUS75800.1 - 0.16 12.8 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 RUS75801.1 - 2.2e-67 227.2 0.2 2.7e-67 226.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS75801.1 - 2.5e-32 112.2 0.1 3e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS75801.1 - 3.4e-05 23.3 0.3 5.8e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS75801.1 - 0.00019 20.5 0.1 0.00028 20.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS75801.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS75801.1 - 0.017 14.5 0.0 0.07 12.4 0.0 1.8 1 1 0 2 2 2 0 Kinase-like NAD_binding_10 PF13460.6 RUS75802.1 - 3.7e-06 27.0 0.0 6.2e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 RUS75802.1 - 0.0096 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 RUS75802.1 - 0.091 11.9 0.0 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein SF-assemblin PF06705.11 RUS75803.1 - 0.021 14.2 1.2 0.64 9.3 0.9 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin Synuclein PF01387.17 RUS75803.1 - 0.2 11.9 5.3 20 5.4 0.2 2.9 1 1 2 3 3 3 0 Synuclein ENTH PF01417.20 RUS75803.1 - 0.55 10.3 5.4 1.5 8.9 2.5 2.4 1 1 1 2 2 2 0 ENTH domain Tmemb_40 PF10160.9 RUS75804.1 - 4.3e-18 65.7 1.8 5.1e-18 65.4 1.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein TPH PF13868.6 RUS75805.1 - 4.9e-05 22.0 0.5 5.4e-05 21.9 0.5 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Integrin_B_tail PF07965.12 RUS75805.1 - 0.084 13.4 2.2 0.11 13.0 2.2 1.2 1 0 0 1 1 1 0 Integrin beta tail domain Gelsolin PF00626.22 RUS75806.1 - 4.4e-37 125.8 0.1 3.5e-16 58.9 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat DUF4028 PF13220.6 RUS75806.1 - 0.11 12.2 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) SecY PF00344.20 RUS75807.1 - 1.9e-77 260.6 10.1 2.2e-77 260.3 10.1 1.0 1 0 0 1 1 1 1 SecY translocase QCR10 PF09796.9 RUS75807.1 - 0.1 12.7 0.3 5.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF5336 PF17270.2 RUS75807.1 - 0.24 11.0 0.0 0.24 11.0 0.0 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5336) DUF2975 PF11188.8 RUS75807.1 - 0.96 9.3 7.1 0.57 10.1 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) C2 PF00168.30 RUS75808.1 - 2.6e-31 108.0 0.0 6.5e-20 71.3 0.1 2.2 2 0 0 2 2 2 2 C2 domain Flot PF15975.5 RUS75808.1 - 0.017 15.3 0.2 0.028 14.6 0.2 1.3 1 0 0 1 1 1 0 Flotillin CEP76-C2 PF15627.6 RUS75808.1 - 0.064 12.8 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Usp PF00582.26 RUS75809.1 - 1.1e-26 94.0 0.0 1.6e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family ABC_membrane PF00664.23 RUS75810.1 - 5.9e-28 98.3 0.2 5.6e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS75810.1 - 1.2e-15 58.3 0.0 1.9e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RUS75810.1 - 0.0036 17.7 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RUS75810.1 - 0.033 14.1 0.4 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 RUS75810.1 - 0.048 13.7 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 RUS75810.1 - 0.05 13.6 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 RUS75810.1 - 0.057 13.2 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RUS75810.1 - 0.084 13.1 0.2 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 RUS75810.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain SMC_N PF02463.19 RUS75810.1 - 0.26 10.7 0.0 0.96 8.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 RUS75811.1 - 2e-10 41.3 0.0 3.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS75811.1 - 0.039 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PRKG1_interact PF15898.5 RUS75812.1 - 2.8e-10 41.0 0.8 4 8.4 0.0 7.1 1 1 6 7 7 7 1 cGMP-dependent protein kinase interacting domain XPC-binding PF09280.11 RUS75812.1 - 7.2e-05 22.4 10.0 1.6 8.5 0.0 5.5 1 1 4 6 6 6 2 XPC-binding domain SSXT PF05030.12 RUS75812.1 - 0.00022 20.8 6.6 8 6.2 0.0 5.9 1 1 6 7 7 7 2 SSXT protein (N-terminal region) Cnn_1N PF07989.11 RUS75812.1 - 0.00039 20.5 1.6 49 4.2 0.3 6.2 4 1 2 6 6 6 0 Centrosomin N-terminal motif 1 RVT_N PF13655.6 RUS75812.1 - 0.044 14.1 13.5 1.3 9.3 1.4 3.5 1 1 3 4 4 4 0 N-terminal domain of reverse transcriptase Wtap PF17098.5 RUS75812.1 - 0.13 12.2 5.7 58 3.6 0.0 4.0 1 1 1 2 2 2 0 WTAP/Mum2p family DUF4327 PF14217.6 RUS75812.1 - 0.94 9.7 15.2 26 5.0 0.5 5.0 3 1 2 5 5 5 0 Domain of unknown function (DUF4327) Phage_holin_2_1 PF04971.12 RUS75812.1 - 1.7 8.7 19.1 28 4.8 0.2 5.8 1 1 6 7 7 7 0 Bacteriophage P21 holin S HTH_9 PF08221.11 RUS75812.1 - 2.6 8.2 7.8 2 8.6 1.0 3.3 1 1 3 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4395 PF14340.6 RUS75812.1 - 2.7 8.3 8.0 1.5 9.2 2.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) Csm1_N PF18504.1 RUS75812.1 - 4.4 7.7 16.4 7.8 6.9 1.1 5.2 1 1 6 7 7 7 0 Csm1 N-terminal domain DUF4709 PF15821.5 RUS75812.1 - 5.1 7.4 14.5 6.3 7.1 5.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) DUF1146 PF06612.11 RUS75813.1 - 0.066 13.3 2.4 21 5.3 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1146) Vanabin-2 PF11437.8 RUS75813.1 - 8.9 6.5 48.2 2.6 8.3 8.6 3.8 1 1 2 3 3 3 0 Vanadium-binding protein 2 Glyco_transf_92 PF01697.27 RUS75814.1 - 6.2e-29 101.4 0.0 8.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS75814.1 - 0.019 15.5 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Exo_endo_phos PF03372.23 RUS75817.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS75817.1 - 0.0042 16.9 0.4 0.0069 16.2 0.4 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TSNAXIP1_N PF15739.5 RUS75818.1 - 3.1e-30 104.8 5.6 3.1e-30 104.8 5.6 3.0 2 1 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Phage_GP20 PF06810.11 RUS75818.1 - 0.0011 18.8 12.0 0.0069 16.2 0.8 2.7 2 0 0 2 2 2 2 Phage minor structural protein GP20 DUF4407 PF14362.6 RUS75818.1 - 0.0043 16.5 9.5 0.009 15.4 9.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) EFG_C PF00679.24 RUS75818.1 - 0.024 14.6 0.1 0.058 13.4 0.1 1.7 1 0 0 1 1 1 0 Elongation factor G C-terminus KxDL PF10241.9 RUS75818.1 - 0.03 14.6 19.9 1.6 9.1 1.7 3.8 2 1 2 4 4 4 0 Uncharacterized conserved protein GAS PF13851.6 RUS75818.1 - 0.051 12.9 22.8 0.56 9.5 3.2 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF848 PF05852.11 RUS75818.1 - 0.09 12.9 15.3 0.18 11.9 0.5 2.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Vps4_C PF09336.10 RUS75818.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain BMFP PF04380.13 RUS75818.1 - 0.4 11.2 5.5 0.27 11.8 0.7 3.3 4 0 0 4 4 3 0 Membrane fusogenic activity TPR_MLP1_2 PF07926.12 RUS75818.1 - 0.45 10.6 27.5 0.58 10.2 9.9 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 RUS75818.1 - 0.74 10.4 11.1 1.7 9.2 2.3 3.1 3 0 0 3 3 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 RUS75818.1 - 1.1 9.4 14.2 1.4 9.0 2.3 3.4 2 1 1 3 3 3 0 bZIP transcription factor MbeD_MobD PF04899.12 RUS75818.1 - 1.2 9.3 6.2 10 6.3 0.9 3.1 2 1 0 2 2 2 0 MbeD/MobD like Lectin_N PF03954.14 RUS75818.1 - 1.7 8.4 8.4 2.8 7.7 3.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4600 PF15372.6 RUS75818.1 - 2.7 8.4 24.5 0.045 14.2 14.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) T2SSF PF00482.23 RUS75818.1 - 2.8 7.9 5.3 0.66 9.9 0.5 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F AKNA PF12443.8 RUS75818.1 - 4.9 7.9 8.6 0.41 11.3 2.5 2.4 2 1 0 2 2 1 0 AT-hook-containing transcription factor DUF737 PF05300.11 RUS75818.1 - 5.8 7.2 16.8 0.32 11.3 6.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF2344 PF10105.9 RUS75818.1 - 6.2 6.6 7.0 1 9.2 0.7 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) Spc7 PF08317.11 RUS75818.1 - 6.5 5.5 22.2 3.2 6.5 2.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein SLC12 PF03522.15 RUS75819.1 - 6.1e-21 75.0 0.3 6.5e-20 71.6 0.3 2.0 1 1 0 1 1 1 1 Solute carrier family 12 RNA_pol_Rpc82 PF05645.13 RUS75819.1 - 0.058 13.1 0.1 0.062 13.0 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 AA_permease PF00324.21 RUS75820.1 - 6.7e-65 219.5 30.0 7.4e-43 146.8 6.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 RUS75820.1 - 1e-14 54.5 2.0 1.7e-14 53.7 0.0 1.9 1 1 1 2 2 2 1 Solute carrier family 12 ECH_1 PF00378.20 RUS75821.1 - 1.2e-34 119.7 0.0 2.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS75821.1 - 1.3e-15 57.7 1.5 1.4e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 RUS75821.1 - 1.1e-12 47.6 0.0 3e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Maf1 PF09174.10 RUS75823.1 - 1e-60 204.9 0.3 1.3e-60 204.5 0.3 1.1 1 0 0 1 1 1 1 Maf1 regulator tRNA-synt_1d PF00750.19 RUS75824.1 - 2.4e-86 289.8 0.1 3.3e-86 289.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RUS75824.1 - 2.8e-21 75.9 0.0 7.1e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 RUS75824.1 - 0.019 14.3 0.0 0.36 10.1 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain CLTH PF10607.9 RUS75825.1 - 2.4e-40 137.9 0.0 3.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 RUS75825.1 - 9.9e-23 80.5 1.1 1.7e-22 79.8 0.2 1.9 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 RUS75825.1 - 8.9e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 LisH SOG2 PF10428.9 RUS75825.1 - 2.7 7.1 17.7 3.6 6.7 17.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NAM-associated PF14303.6 RUS75825.1 - 2.7 8.7 9.3 0.49 11.1 2.8 2.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Ndc1_Nup PF09531.10 RUS75825.1 - 3.8 6.1 7.4 4.9 5.7 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 RUS75825.1 - 6.3 5.3 10.3 8.6 4.9 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein Arrestin_N PF00339.29 RUS75826.1 - 8.3e-24 84.3 0.0 2.6e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS75826.1 - 2.1e-09 38.0 0.0 8.1e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS75826.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Rgp1 Vps26 PF03643.15 RUS75826.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 IBN_N PF03810.19 RUS75828.1 - 1.3e-11 44.3 1.9 3.6e-11 42.8 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_C PF08767.11 RUS75828.1 - 0.0076 15.5 0.5 0.019 14.2 0.1 1.8 2 0 0 2 2 2 1 CRM1 C terminal HEAT_2 PF13646.6 RUS75828.1 - 0.0091 16.4 0.1 0.035 14.5 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats DUF2430 PF10353.9 RUS75828.1 - 0.017 15.5 2.8 0.08 13.3 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Sulfate_transp PF00916.20 RUS75829.1 - 6.4e-97 324.7 21.9 6.4e-97 324.7 21.9 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 RUS75829.1 - 4.4e-19 68.2 0.1 7.6e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain Tim17 PF02466.19 RUS75829.1 - 1.4 9.4 4.3 2.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Plasmodium_HRP PF05403.11 RUS75831.1 - 3.7e-10 40.0 25.8 0.00033 20.5 6.0 3.0 1 1 2 3 3 3 3 Plasmodium histidine-rich protein (HRPII/III) DEAD PF00270.29 RUS75832.1 - 8.2e-56 188.5 0.0 1.5e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS75832.1 - 7.6e-27 93.9 0.0 3.8e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 RUS75832.1 - 4e-20 72.1 1.2 5e-20 71.8 0.2 1.7 2 0 0 2 2 2 1 SPRY domain 7tm_1 PF00001.21 RUS75833.1 - 7.3e-11 41.9 22.5 9.6e-11 41.5 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS75833.1 - 0.00027 20.3 17.3 0.00099 18.5 14.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Gemini_mov PF01708.16 RUS75833.1 - 3.2 7.6 5.2 0.36 10.6 0.3 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF1230 PF06799.11 RUS75833.1 - 5.6 7.1 12.3 7.2 6.7 5.2 2.4 1 1 1 2 2 2 0 Conserved in the green lineage and diatoms 27 Exo_endo_phos_2 PF14529.6 RUS75834.1 - 0.035 14.0 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase FMP23 PF17315.2 RUS75834.1 - 0.044 13.9 0.2 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Found in mitochondrial proteome Exo_endo_phos PF03372.23 RUS75834.1 - 0.078 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3288 PF11691.8 RUS75834.1 - 0.11 12.6 0.6 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) DUF807 PF05660.11 RUS75834.1 - 0.16 12.0 0.1 0.44 10.5 0.0 1.7 2 0 0 2 2 2 0 Coxiella burnetii protein of unknown function (DUF807) GST_C PF00043.25 RUS75835.1 - 0.0016 18.6 1.0 11 6.3 0.0 4.1 1 1 2 4 4 4 1 Glutathione S-transferase, C-terminal domain YuiB PF14068.6 RUS75835.1 - 0.0028 18.2 10.5 2.8 8.6 0.1 4.6 1 1 3 4 4 4 1 Putative membrane protein DUF4745 PF15923.5 RUS75835.1 - 0.083 12.9 8.9 23 5.0 0.1 5.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4745) ENOD93 PF03386.14 RUS75835.1 - 0.98 9.3 12.4 16 5.5 0.1 5.7 1 1 3 5 5 5 0 Early nodulin 93 ENOD93 protein DUF5409 PF17421.2 RUS75835.1 - 2.2 9.1 18.8 23 5.8 0.6 4.8 1 1 3 4 4 4 0 Family of unknown function (DUF5409) PepX_N PF09168.10 RUS75835.1 - 5 7.5 10.0 40 4.6 0.1 4.2 3 1 2 5 5 5 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Apq12 PF12716.7 RUS75835.1 - 5.7 7.0 17.4 16 5.5 0.8 5.7 1 1 5 7 7 7 0 Nuclear pore assembly and biogenesis ECH_1 PF00378.20 RUS75836.1 - 1.7e-21 76.6 0.0 2.2e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS75836.1 - 7.2e-06 25.7 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Linker_histone PF00538.19 RUS75838.1 - 1.2e-31 108.9 0.4 2.6e-13 50.1 0.0 4.4 4 0 0 4 4 4 3 linker histone H1 and H5 family RFX_DNA_binding PF02257.15 RUS75838.1 - 7.4e-06 26.5 0.0 1.9e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain CBM_14 PF01607.24 RUS75839.1 - 4.1e-36 122.9 40.0 7.8e-09 35.6 3.9 4.8 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain Phage_glycop_gL PF11108.8 RUS75839.1 - 3.4e-06 27.0 3.7 8.8 6.4 0.0 4.2 4 0 0 4 4 4 4 Viral glycoprotein L DEFB136 PF17333.2 RUS75839.1 - 0.00018 21.4 4.6 23 5.0 0.1 4.7 4 0 0 4 4 4 0 Beta defensin 136 Cerato-platanin PF07249.12 RUS75839.1 - 0.00074 19.6 2.2 50 4.1 0.0 4.1 4 0 0 4 4 4 0 Cerato-platanin CIMR PF00878.18 RUS75839.1 - 0.0087 16.1 2.9 74 3.4 0.0 4.1 4 0 0 4 4 4 0 Cation-independent mannose-6-phosphate receptor repeat Mx_ML PF17536.2 RUS75839.1 - 0.05 13.3 0.3 1.6e+02 1.9 0.0 3.8 4 0 0 4 4 4 0 Matrix and Matrix long proteins N-terminal ATP-synt_S1 PF05827.12 RUS75839.1 - 0.74 9.6 6.7 78 3.1 0.1 4.0 4 0 0 4 4 4 0 Vacuolar ATP synthase subunit S1 (ATP6S1) SSP160 PF06933.11 RUS75839.1 - 1.2 7.2 8.8 6 4.9 0.2 3.3 4 0 0 4 4 4 0 Special lobe-specific silk protein SSP160 PMP22_Claudin PF00822.20 RUS75840.1 - 1.8e-08 34.5 13.5 2.3e-08 34.1 13.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS75840.1 - 1.9e-08 34.3 20.5 4.9e-05 23.2 20.5 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 RUS75840.1 - 0.00055 19.5 2.4 0.00055 19.5 2.4 2.5 1 1 1 2 2 2 1 Clc-like Claudin_3 PF06653.11 RUS75840.1 - 0.0017 18.4 13.0 0.0051 16.8 13.3 1.6 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF4131 PF13567.6 RUS75840.1 - 0.04 13.6 0.1 0.04 13.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 RUS75840.1 - 0.34 11.2 12.0 3 8.2 12.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MpPF26 PF07666.11 RUS75840.1 - 6.4 6.9 11.8 0.19 11.8 2.6 2.7 2 1 1 3 3 3 0 M penetrans paralogue family 26 LRR_4 PF12799.7 RUS75842.1 - 2.3e-05 24.6 9.2 0.0018 18.6 1.9 3.1 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS75842.1 - 8.8e-05 22.3 8.1 0.24 11.5 0.2 3.9 4 0 0 4 4 4 3 Leucine Rich repeat Integrase_Zn PF02022.19 RUS75842.1 - 0.00063 19.7 0.4 0.0027 17.6 0.4 2.2 2 0 0 2 2 2 1 Integrase Zinc binding domain LRR_8 PF13855.6 RUS75842.1 - 0.057 13.2 9.4 0.31 10.8 3.0 2.8 2 1 1 3 3 3 0 Leucine rich repeat CxC6 PF18721.1 RUS75842.1 - 0.71 10.2 4.7 0.34 11.2 1.4 2.0 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases LRR_1 PF00560.33 RUS75842.1 - 1.3 9.9 18.9 12 7.0 4.4 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat Neur_chan_LBD PF02931.23 RUS75843.1 - 4.7e-37 127.5 0.6 3.6e-35 121.4 0.6 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS75843.1 - 3.3e-27 96.1 2.9 5.2e-26 92.2 0.5 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF5021 PF16424.5 RUS75843.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) DUF5392 PF17370.2 RUS75843.1 - 0.21 11.7 1.0 0.36 10.9 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) GDPD PF03009.17 RUS75845.1 - 0.043 13.6 0.1 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family IgaA PF07095.11 RUS75845.1 - 0.092 10.7 0.4 0.17 9.8 0.1 1.5 2 0 0 2 2 2 0 Intracellular growth attenuator protein IgaA Zip PF02535.22 RUS75845.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CsgF PF10614.9 RUS75845.1 - 0.78 10.0 8.1 2 8.7 1.9 2.3 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein p450 PF00067.22 RUS75846.1 - 5.6e-94 315.5 0.0 7.4e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ndc1_Nup PF09531.10 RUS75846.1 - 0.2 10.3 2.1 0.29 9.8 2.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PGM_PMM_I PF02878.16 RUS75847.1 - 2.7e-35 121.1 0.0 4.5e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RUS75847.1 - 3.5e-31 107.7 0.0 7.3e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RUS75847.1 - 1.6e-15 57.6 0.0 3.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RUS75847.1 - 6.2e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Aa_trans PF01490.18 RUS75848.1 - 1.4e-30 106.4 36.8 1.4e-16 60.2 21.7 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein BTB_2 PF02214.22 RUS75849.1 - 5.3e-14 52.3 0.0 7.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain eIF2A PF08662.11 RUS75850.1 - 4.1e-62 209.5 0.0 4e-60 203.0 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup88 PF10168.9 RUS75850.1 - 0.06 11.2 0.1 0.094 10.5 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore component Med4 PF10018.9 RUS75851.1 - 9.3e-30 103.7 0.3 1.5e-29 103.1 0.3 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Sec5 PF15469.6 RUS75851.1 - 0.053 13.3 0.4 0.073 12.9 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 CREPT PF16566.5 RUS75851.1 - 0.22 11.7 5.3 0.33 11.1 5.3 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Spc7 PF08317.11 RUS75851.1 - 0.47 9.3 6.4 0.62 8.9 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 RUS75851.1 - 0.53 10.5 7.8 0.82 9.9 7.8 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Dad2 PF08654.10 RUS75851.1 - 0.91 10.0 6.4 1.4 9.4 6.4 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 FeoB_Cyto PF17910.1 RUS75851.1 - 2.6 8.7 6.8 27 5.4 6.8 2.1 1 1 0 1 1 1 0 FeoB cytosolic helical domain Glyco_hydro_35 PF01301.19 RUS75852.1 - 1.8e-18 67.2 0.2 2.6e-18 66.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 RUS75852.1 - 0.0025 18.4 0.4 2.1 8.9 0.0 3.4 3 1 0 3 3 3 1 Beta-galactosidase jelly roll domain PHD PF00628.29 RUS75853.1 - 2.8e-06 27.1 8.6 5.9e-06 26.1 8.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RUS75853.1 - 0.0022 17.9 2.5 0.0022 17.9 2.5 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RUS75853.1 - 0.013 15.0 6.5 0.24 11.0 0.1 2.7 3 0 0 3 3 3 0 PHD-finger PHD_Oberon PF07227.11 RUS75853.1 - 0.016 15.0 5.2 0.036 13.9 4.8 1.8 1 1 0 1 1 1 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 RUS75853.1 - 0.13 12.2 5.2 0.31 11.0 5.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 RUS75853.1 - 0.26 11.6 6.6 0.31 11.4 3.7 2.1 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 RUS75853.1 - 0.5 10.5 5.2 1.4 9.1 5.2 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger DUF5383 PF17355.2 RUS75854.1 - 7.8e-05 23.0 32.0 0.15 12.4 3.2 4.2 1 1 2 4 4 4 4 Family of unknown function (DUF5383) Glyco_hydro_4 PF02056.16 RUS75854.1 - 0.016 14.8 4.9 6.4 6.3 0.1 3.3 1 1 3 4 4 4 0 Family 4 glycosyl hydrolase Ammonium_transp PF00909.21 RUS75855.1 - 1.6e-76 257.6 20.3 2.3e-76 257.1 20.3 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4728 PF15860.5 RUS75855.1 - 2.2 9.0 8.5 0.44 11.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4728) CBM_14 PF01607.24 RUS75856.1 - 1.9e-28 98.4 39.9 1.1e-08 35.1 0.8 7.3 6 1 1 7 7 7 6 Chitin binding Peritrophin-A domain Paf1 PF03985.13 RUS75858.1 - 6.9 5.6 6.5 10 5.0 6.5 1.2 1 0 0 1 1 1 0 Paf1 7tm_2 PF00002.24 RUS75859.1 - 5.1e-07 29.2 0.2 7.4e-07 28.7 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Xan_ur_permease PF00860.20 RUS75861.1 - 2.1e-15 56.3 7.9 3.1e-10 39.3 2.3 2.1 2 0 0 2 2 2 2 Permease family Mito_fiss_reg PF05308.11 RUS75861.1 - 1.1 9.3 2.9 1.6 8.8 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator FB_lectin PF07367.11 RUS75862.1 - 0.84 9.6 3.9 2.1 8.3 2.1 2.3 1 1 1 2 2 2 0 Fungal fruit body lectin DUF150 PF02576.17 RUS75862.1 - 1.2 9.6 3.6 14 6.2 0.4 2.2 1 1 0 2 2 2 0 RimP N-terminal domain FANCI_S4 PF14678.6 RUS75863.1 - 0.093 11.8 1.2 0.82 8.7 0.6 2.4 2 0 0 2 2 2 0 FANCI solenoid 4 LRR_2 PF07723.13 RUS75864.1 - 1.7e-05 25.2 2.1 10 7.0 0.1 5.6 2 1 4 6 6 6 3 Leucine Rich Repeat Ribosomal_L33 PF00471.20 RUS75864.1 - 0.0071 16.8 33.5 9.5 6.8 0.2 7.1 1 1 6 7 7 7 7 Ribosomal protein L33 zf-CCHH PF10283.9 RUS75864.1 - 0.88 9.6 10.7 3.3e+02 1.4 0.0 6.5 8 0 0 8 8 8 0 PBZ domain C4bp_oligo PF18453.1 RUS75865.1 - 4e-10 39.7 12.3 1.7 8.9 0.2 6.9 1 1 6 7 7 7 6 Oligomerization domain of C4b-binding protein alpha TEP1_N PF05386.11 RUS75865.1 - 0.0066 16.0 12.2 46 3.7 0.0 6.7 7 0 0 7 7 7 0 TEP1 N-terminal domain Baculo_PEP_C PF04513.12 RUS75865.1 - 0.057 13.5 2.6 0.14 12.2 2.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CagY_M PF07337.11 RUS75865.1 - 0.12 12.1 10.8 74 3.1 0.3 6.3 4 2 1 5 5 5 0 DC-EC Repeat DUF3730 PF12530.8 RUS75865.1 - 0.25 10.9 12.3 4.2 6.9 2.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3730) DUF547 PF04784.14 RUS75865.1 - 0.73 9.9 4.0 13 5.8 4.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF547 PUL PF08324.11 RUS75865.1 - 3.5 6.8 7.3 6.9 5.8 1.1 2.0 1 1 1 2 2 2 0 PUL domain Pepdidase_M14_N PF18027.1 RUS75866.1 - 8.7e-13 48.6 1.0 4.4e-12 46.3 0.1 2.6 2 1 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 RUS75866.1 - 3.3e-11 43.5 0.0 1.1e-10 41.9 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase C2 PF00168.30 RUS75867.1 - 1.6e-24 86.1 0.1 2e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 C2 domain DUF5521 PF17659.1 RUS75868.1 - 0.69 7.7 3.2 0.86 7.4 3.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Vma12 PF11712.8 RUS75870.1 - 0.031 14.3 0.9 0.067 13.3 0.9 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase OTU PF02338.19 RUS75871.1 - 0.0047 17.4 0.1 0.0053 17.3 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease UPF0242 PF06785.11 RUS75873.1 - 0.0013 18.9 16.9 0.0013 18.9 16.9 9.4 2 1 5 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus DUF3305 PF11749.8 RUS75874.1 - 4.7e-12 46.2 25.3 85 3.3 0.1 17.9 1 1 20 21 21 21 0 Protein of unknown function (DUF3305) DUF1576 PF07613.11 RUS75874.1 - 1.6e-08 34.3 37.4 3.5 7.1 0.5 8.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1576) PGM_PMM_I PF02878.16 RUS75874.1 - 0.00076 19.2 29.1 58 3.4 0.5 9.6 1 1 17 18 18 18 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Pentapeptide_4 PF13599.6 RUS75875.1 - 9.6e-09 35.3 25.7 0.23 11.7 1.2 5.8 1 1 5 6 6 6 6 Pentapeptide repeats (9 copies) DUF2807 PF10988.8 RUS75875.1 - 0.0002 21.2 9.7 0.12 12.1 0.4 3.1 1 1 2 3 3 3 3 Putative auto-transporter adhesin, head GIN domain DUF3703 PF12487.8 RUS75875.1 - 0.024 14.4 35.4 0.56 10.1 2.6 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF3703) DUF719 PF05334.13 RUS75876.1 - 6.4 6.9 10.2 0.51 10.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) RNase_H PF00075.24 RUS75877.1 - 1.3e-12 48.2 2.7 2.3e-12 47.3 0.2 2.5 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS75877.1 - 0.019 14.7 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like LytR_C PF13399.6 RUS75877.1 - 0.11 13.4 0.5 7.5 7.6 0.1 2.6 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF1244 PF06844.11 RUS75877.1 - 0.11 12.6 0.4 0.3 11.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) RNase_H2_suC PF08615.11 RUS75879.1 - 0.17 12.1 4.7 3.3 7.9 4.6 2.7 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4770 PF15994.5 RUS75879.1 - 1.9 8.7 13.1 4.2 7.6 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) SelP_N PF04592.14 RUS75879.1 - 9 5.6 18.2 0.018 14.5 3.2 2.5 3 0 0 3 3 3 0 Selenoprotein P, N terminal region EIF4E-T PF10477.9 RUS75881.1 - 3.8e-48 164.8 55.7 3.8e-48 164.8 55.7 2.3 1 1 0 2 2 2 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E W2 PF02020.18 RUS75884.1 - 1.9e-20 72.8 1.8 1.9e-20 72.8 1.8 3.5 4 1 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Dpoe2NT PF12213.8 RUS75884.1 - 0.0004 20.6 0.3 0.009 16.3 0.2 2.6 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal FAIM1 PF06905.13 RUS75885.1 - 5.9e-82 273.6 2.7 6.6e-82 273.4 2.7 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) BTB PF00651.31 RUS75886.1 - 1.7e-33 115.2 0.9 2.9e-33 114.4 0.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 RUS75886.1 - 3.8e-09 36.7 0.2 4.9e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 RUS75886.1 - 0.00096 19.2 0.5 0.029 14.5 0.0 3.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch PgaD PF13994.6 RUS75887.1 - 0.076 13.1 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein SLC3A2_N PF16028.5 RUS75887.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus SH3BP5 PF05276.14 RUS75889.1 - 6.3e-89 297.7 23.0 6.3e-89 297.7 23.0 1.8 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Myb_Cef PF11831.8 RUS75890.1 - 0.087 12.4 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 pre-mRNA splicing factor component Mucin PF01456.17 RUS75890.1 - 0.82 9.7 23.0 0.41 10.6 18.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 RUS75890.1 - 1 9.8 14.8 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 RUS75890.1 - 1.4 7.0 14.8 2.1 6.5 14.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 RUS75890.1 - 6.8 4.5 8.7 9 4.1 8.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APC_u15 PF16636.5 RUS75891.1 - 0.19 12.2 1.1 11 6.5 0.2 2.8 2 2 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF356 PF04009.12 RUS75891.1 - 0.8 10.0 6.3 21 5.4 2.3 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF356) DUF2381 PF09544.10 RUS75892.1 - 0.052 13.1 0.5 0.052 13.1 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) AAA_23 PF13476.6 RUS75892.1 - 0.47 10.9 23.1 0.092 13.2 0.8 3.2 2 1 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 RUS75893.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS75893.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L27A PF00828.19 RUS75893.1 - 0.04 14.6 0.0 0.074 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_1 PF00561.20 RUS75894.1 - 2.6e-05 24.0 0.1 4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS75894.1 - 0.00023 20.5 0.1 0.00029 20.2 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SH2 PF00017.24 RUS75895.1 - 6.1e-13 48.7 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 RUS75895.1 - 1.5e-10 40.8 7.6 1.5e-10 40.8 7.6 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.27 RUS75895.1 - 1.9e-09 37.6 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_2 PF03107.16 RUS75895.1 - 4.5 7.7 15.7 0.36 11.2 3.4 2.7 2 0 0 2 2 2 0 C1 domain DUF2076 PF09849.9 RUS75897.1 - 1.5 8.8 3.1 2.3 8.2 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ldl_recept_a PF00057.18 RUS75898.1 - 5.6e-13 48.9 9.2 3.3e-07 30.4 3.9 3.8 3 1 1 4 4 4 2 Low-density lipoprotein receptor domain class A cEGF PF12662.7 RUS75898.1 - 0.00099 19.0 13.6 0.0032 17.4 1.2 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS75898.1 - 0.0033 17.6 12.0 0.0033 17.6 12.0 4.3 3 1 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS75898.1 - 0.017 15.4 6.9 0.017 15.4 6.9 3.5 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Tme5_EGF_like PF09064.10 RUS75898.1 - 0.034 14.0 7.2 0.034 14.0 7.2 3.2 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Ldl_recept_a PF00057.18 RUS75899.1 - 1.5e-165 537.1 351.7 6.6e-12 45.4 9.8 23.7 22 0 0 22 22 22 20 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 RUS75899.1 - 5.5e-70 231.6 34.2 1.6e-06 28.5 0.3 17.3 16 2 0 16 16 16 13 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 RUS75899.1 - 4.2e-18 65.3 57.1 6.5e-08 32.7 11.5 22.3 17 3 4 21 21 21 7 Coagulation Factor Xa inhibitory site SGL PF08450.12 RUS75899.1 - 4.7e-14 52.6 11.6 0.021 14.4 0.0 8.9 6 4 1 7 7 7 5 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 RUS75899.1 - 1.4e-12 47.5 0.1 0.0057 15.9 0.0 6.8 5 3 1 7 7 7 2 Domain of unknown function (DUF5050) cEGF PF12662.7 RUS75899.1 - 3.8e-10 39.5 7.3 4.2e-07 29.8 0.8 16.0 17 0 0 17 17 17 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS75899.1 - 2.4e-08 34.0 9.5 2.4e-08 34.0 9.5 28.2 20 8 10 30 30 30 2 Calcium-binding EGF domain EGF PF00008.27 RUS75899.1 - 9.9e-06 25.8 38.0 0.00022 21.5 7.9 26.2 25 4 4 30 30 30 9 EGF-like domain Arylesterase PF01731.20 RUS75899.1 - 0.00043 20.4 0.0 13 6.1 0.0 5.4 5 1 1 6 6 6 1 Arylesterase EGF_2 PF07974.13 RUS75899.1 - 0.0064 16.8 12.9 0.0064 16.8 12.9 21.5 23 3 3 26 26 26 3 EGF-like domain PAN_1 PF00024.26 RUS75900.1 - 8e-14 51.4 29.2 2.2e-06 27.5 4.1 4.0 4 0 0 4 4 4 3 PAN domain PMP22_Claudin PF00822.20 RUS75901.1 - 6.9e-09 35.8 16.4 9.8e-07 28.8 9.4 2.0 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS75901.1 - 8.9e-07 28.8 16.0 8.9e-07 28.8 16.0 2.5 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS75901.1 - 8.3e-05 22.6 15.8 9.8e-05 22.3 15.8 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Trp_oprn_chp PF09534.10 RUS75901.1 - 0.053 13.3 4.4 0.089 12.6 4.4 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 RUS75901.1 - 0.092 12.6 15.6 0.2 11.5 15.6 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein GWT1 PF06423.12 RUS75901.1 - 0.12 12.5 3.8 0.17 12.0 3.8 1.3 1 0 0 1 1 1 0 GWT1 Cation_ATPase_C PF00689.21 RUS75901.1 - 1 9.0 10.3 1.7 8.3 10.3 1.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus CD20 PF04103.15 RUS75901.1 - 1.7 8.7 17.5 1.3 9.1 4.2 3.0 1 1 2 3 3 3 0 CD20-like family DUF973 PF06157.11 RUS75901.1 - 4.6 6.2 13.8 39 3.2 13.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Phage_holin_1 PF04531.13 RUS75901.1 - 6.9 7.3 9.2 0.64 10.6 1.8 2.6 3 0 0 3 3 3 0 Bacteriophage holin TM2 PF05154.16 RUS75902.1 - 1.9e-38 130.5 60.5 4.6e-11 42.9 13.5 4.1 4 0 0 4 4 4 4 TM2 domain EmrE PF13536.6 RUS75902.1 - 0.65 9.5 2.8 14 5.1 0.3 2.2 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter Arteri_Gl PF00951.18 RUS75905.1 - 0.049 13.4 0.6 0.065 13.1 0.6 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein zf-C2H2 PF00096.26 RUS75908.1 - 1.2e-06 28.7 13.4 0.0031 17.9 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS75908.1 - 8.7e-06 26.2 13.3 0.42 11.6 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger PhaC_N PF07167.13 RUS75908.1 - 0.02 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus zf-Di19 PF05605.12 RUS75908.1 - 0.037 14.3 4.6 0.037 14.3 4.6 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RUS75908.1 - 0.039 14.0 7.6 8.8 6.5 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 RUS75908.1 - 0.099 13.1 8.0 7.1 7.2 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RUS75908.1 - 0.67 10.5 13.8 3.3 8.3 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HE PF16278.5 RUS75908.1 - 2.6 8.5 5.9 0.99 9.9 2.2 2.4 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 RUS75908.1 - 4.6 7.6 11.9 0.85 10.0 1.3 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RUS75908.1 - 8.4 6.8 12.7 7.9 6.9 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 RUS75909.1 - 2.5e-41 141.6 0.3 9.3e-41 139.8 0.3 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHQS PF01959.16 RUS75909.1 - 0.032 13.1 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II SQS_PSY PF00494.19 RUS75910.1 - 5e-17 62.3 0.0 5.5e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Squalene/phytoene synthase GAS PF13851.6 RUS75910.1 - 0.00028 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4644 PF15486.6 RUS75911.1 - 0.012 15.4 0.3 0.023 14.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) Peptidase_C3 PF00548.20 RUS75912.1 - 0.0059 16.6 1.2 3.4 7.6 0.1 2.5 2 0 0 2 2 2 2 3C cysteine protease (picornain 3C) PKI PF02827.16 RUS75913.1 - 3.3e-12 46.4 0.3 6e-12 45.6 0.3 1.4 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Ras PF00071.22 RUS75914.1 - 1.1e-32 112.8 0.1 2.1e-19 69.7 0.0 3.2 2 1 1 3 3 3 3 Ras family Roc PF08477.13 RUS75914.1 - 2.6e-14 53.4 0.0 5.7e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RUS75914.1 - 0.0021 17.6 0.0 0.11 12.1 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RUS75914.1 - 0.0061 16.3 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation OCIA PF07051.11 RUS75914.1 - 0.031 14.3 0.0 20 5.3 0.0 3.0 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) Arf PF00025.21 RUS75914.1 - 0.1 12.0 0.1 3.8 6.9 0.0 2.6 2 1 1 3 3 3 0 ADP-ribosylation factor family TniB PF05621.11 RUS75914.1 - 0.17 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein BKACE PF05853.12 RUS75914.1 - 0.19 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme DUF4064 PF13273.6 RUS75915.1 - 0.1 12.9 6.0 6.1 7.2 3.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Amastin PF07344.11 RUS75915.1 - 0.17 11.7 14.2 0.012 15.5 7.0 2.2 1 1 0 2 2 2 0 Amastin surface glycoprotein CBFD_NFYB_HMF PF00808.23 RUS75916.1 - 3.3e-11 43.3 0.0 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS75916.1 - 0.0073 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CEP44 PF15007.6 RUS75916.1 - 0.026 14.7 0.0 0.031 14.5 0.0 1.0 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 DUF4119 PF13494.6 RUS75916.1 - 0.089 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Tegument_dsDNA PF12818.7 RUS75916.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein Sulfotransfer_3 PF13469.6 RUS75917.1 - 2.6e-08 34.5 0.1 0.0018 18.7 0.1 2.1 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS75917.1 - 0.00016 21.2 0.2 0.00036 20.1 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Kelch_3 PF13415.6 RUS75917.1 - 0.0061 16.8 2.6 0.71 10.2 0.1 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Sulfotransfer_2 PF03567.14 RUS75917.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family HEAT PF02985.22 RUS75918.1 - 3.6e-13 48.5 3.9 0.082 13.2 0.1 7.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 RUS75918.1 - 5.6e-11 42.7 0.4 0.045 14.3 0.0 6.4 3 2 2 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 RUS75918.1 - 2.7e-09 37.3 0.2 0.015 15.7 0.0 6.2 4 1 2 6 6 6 2 HEAT repeats CLASP_N PF12348.8 RUS75918.1 - 1.4e-05 24.7 2.0 0.64 9.5 0.1 4.6 3 1 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 RUS75918.1 - 1.5e-05 25.1 4.6 1.2 9.1 0.0 6.1 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RUS75918.1 - 0.00071 20.1 0.0 1.6 9.4 0.0 5.2 4 1 2 6 6 6 2 Vacuolar 14 Fab1-binding region DUF4042 PF13251.6 RUS75918.1 - 0.027 14.2 0.9 4.2 7.0 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) IFRD PF05004.13 RUS75918.1 - 0.06 12.5 6.9 0.15 11.1 0.0 4.4 3 2 0 4 4 4 0 Interferon-related developmental regulator (IFRD) UME PF08064.13 RUS75918.1 - 0.098 12.6 3.9 6 6.8 0.0 5.0 4 1 0 4 4 4 0 UME (NUC010) domain TIP120 PF08623.10 RUS75918.1 - 0.19 11.5 8.0 2.5 7.8 0.1 5.2 5 1 0 5 5 5 0 TATA-binding protein interacting (TIP20) ARL2_Bind_BART PF11527.8 RUS75919.1 - 2.8e-30 104.8 9.3 3.8e-30 104.4 9.3 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Reprolysin PF01421.19 RUS75920.1 - 3.8e-08 33.5 1.4 5.8e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 RUS75920.1 - 1.9e-06 28.3 2.5 1.9e-06 28.3 2.5 2.1 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 RUS75920.1 - 0.0092 16.2 0.7 0.016 15.4 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS75920.1 - 0.016 15.1 0.9 0.04 13.8 0.6 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Rsm22 PF09243.10 RUS75921.1 - 8e-51 172.9 0.0 1.3e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Y_phosphatase PF00102.27 RUS75922.1 - 7.7e-73 244.9 0.0 1.3e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS75922.1 - 0.0037 17.1 0.1 0.0094 15.8 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS75922.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Ldl_recept_a PF00057.18 RUS75923.1 - 2e-09 37.5 9.7 2e-09 37.5 9.7 4.2 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A CUB PF00431.20 RUS75923.1 - 1.5e-08 34.9 0.0 9e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 CUB domain Syndecan PF01034.20 RUS75923.1 - 0.56 10.2 1.5 1 9.4 1.5 1.4 1 0 0 1 1 1 0 Syndecan domain TPR_19 PF14559.6 RUS75925.1 - 0.00012 22.5 1.2 0.12 12.9 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 RUS75925.1 - 0.00046 19.9 0.3 0.024 14.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 RUS75925.1 - 0.0025 18.5 0.8 0.059 14.2 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS75925.1 - 0.018 15.3 1.6 8.8 6.6 0.2 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RUS75925.1 - 0.025 14.7 1.0 7.5 6.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS75925.1 - 0.038 14.3 0.9 1.4 9.3 1.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat HMW1C_N PF18071.1 RUS75925.1 - 0.042 13.7 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 HMW1C N-terminal TPR_6 PF13174.6 RUS75925.1 - 0.11 13.2 0.3 7.7 7.4 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 RUS75926.1 - 1.7e-47 161.8 0.1 3.9e-47 160.6 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.27 RUS75927.1 - 0.0072 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RUS75927.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RUS75927.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain LSM_int_assoc PF16605.5 RUS75927.1 - 0.086 13.0 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 LSM-interacting associated unstructured AAA_7 PF12775.7 RUS75927.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 RUS75927.1 - 0.14 11.9 0.0 0.78 9.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 RUS75927.1 - 0.14 12.4 0.3 0.21 11.9 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RUS75927.1 - 0.21 12.0 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 RUS75928.1 - 2.3e-16 60.1 0.0 5.1e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS75928.1 - 0.00019 21.3 0.1 0.0089 15.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase SPRY PF00622.28 RUS75929.1 - 5.4e-15 55.6 3.4 1e-07 32.1 0.2 4.2 4 1 0 4 4 4 3 SPRY domain SPRY PF00622.28 RUS75930.1 - 1e-12 48.2 0.1 1.1e-11 44.9 0.1 2.2 2 0 0 2 2 2 1 SPRY domain LRR_8 PF13855.6 RUS75931.1 - 2.6e-08 33.5 6.5 0.00012 21.7 1.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS75931.1 - 2.3e-05 24.7 11.8 0.023 15.1 0.2 4.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS75931.1 - 0.032 14.7 3.7 1.1 10.0 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat COR PF16095.5 RUS75932.1 - 2.9e-49 167.6 1.5 5e-49 166.8 0.7 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 RUS75932.1 - 6.4e-25 87.7 0.1 6.8e-23 81.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TIR_2 PF13676.6 RUS75932.1 - 2.7e-22 79.6 0.2 4.3e-11 43.4 0.0 4.2 4 0 0 4 4 3 2 TIR domain Ras PF00071.22 RUS75932.1 - 1.8e-12 47.2 0.0 9.9e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Ras family LRR_8 PF13855.6 RUS75932.1 - 6.3e-08 32.3 2.2 1.3e-07 31.3 2.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat TIR PF01582.20 RUS75932.1 - 7.1e-07 29.2 1.8 9.7e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 TIR domain LRR_4 PF12799.7 RUS75932.1 - 2.8e-05 24.4 8.8 0.0012 19.2 2.3 2.7 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) RsgA_GTPase PF03193.16 RUS75932.1 - 0.00063 19.7 0.0 0.32 10.9 0.1 3.0 3 0 0 3 3 3 1 RsgA GTPase Arf PF00025.21 RUS75932.1 - 0.0016 17.9 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 RUS75932.1 - 0.0017 18.8 1.6 0.0042 17.6 0.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.6 RUS75932.1 - 0.021 15.2 1.7 0.13 12.6 0.1 2.9 4 0 0 4 4 4 0 AAA ATPase domain MMR_HSR1 PF01926.23 RUS75932.1 - 0.038 14.1 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Peptidase_S49_N PF08496.10 RUS75932.1 - 0.048 13.7 2.2 0.1 12.6 2.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_21 PF13304.6 RUS75932.1 - 0.09 12.6 0.8 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 RUS75932.1 - 0.22 11.1 0.3 0.56 9.8 0.3 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain LRR_1 PF00560.33 RUS75932.1 - 0.77 10.5 3.2 3.2 8.7 0.1 3.5 3 0 0 3 3 2 0 Leucine Rich Repeat CHIP_TPR_N PF18391.1 RUS75933.1 - 0.064 14.0 0.1 0.089 13.6 0.1 1.3 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain PTPS PF01242.19 RUS75934.1 - 1.4e-33 115.5 0.1 1.6e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase MRP-S26 PF14943.6 RUS75935.1 - 8.5e-31 107.1 15.6 1e-30 106.9 15.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 ECM1 PF05782.11 RUS75935.1 - 0.0038 16.2 6.0 0.0044 16.0 6.0 1.0 1 0 0 1 1 1 1 Extracellular matrix protein 1 (ECM1) PIEZO PF15917.5 RUS75935.1 - 0.058 12.9 7.3 0.076 12.5 7.3 1.2 1 0 0 1 1 1 0 Piezo HPPK PF01288.20 RUS75935.1 - 0.083 13.4 0.7 0.13 12.8 0.7 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3126 PF11324.8 RUS75935.1 - 0.12 12.2 0.5 0.12 12.2 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3126) NDUF_B5 PF09781.9 RUS75935.1 - 0.29 10.7 5.8 0.51 9.9 5.8 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Mad3_BUB1_I_2 PF17014.5 RUS75935.1 - 0.41 10.8 5.3 0.92 9.6 1.1 2.3 1 1 1 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Phage_GPO PF05929.11 RUS75935.1 - 0.42 10.2 8.5 0.53 9.9 8.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPK_catalytic PF04263.16 RUS75935.1 - 0.53 10.3 3.5 0.98 9.5 2.3 2.0 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain PCRF PF03462.18 RUS75935.1 - 7.3 6.4 12.2 10 5.9 12.2 1.3 1 0 0 1 1 1 0 PCRF domain PTPlike_phytase PF14566.6 RUS75935.1 - 8.1 6.5 11.6 7.5 6.7 8.2 2.4 2 1 0 2 2 2 0 Inositol hexakisphosphate WRNPLPNID PF15017.6 RUS75935.1 - 9.6 7.2 8.8 1.4e+02 3.4 8.8 2.4 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box TMEM154 PF15102.6 RUS75937.1 - 0.087 12.7 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family DUF908 PF06012.12 RUS75938.1 - 0.26 10.7 3.1 0.32 10.4 3.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PKD_channel PF08016.12 RUS75939.1 - 4.8e-55 187.0 15.4 4.8e-55 187.0 15.4 2.0 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 RUS75939.1 - 1.3e-32 113.2 0.0 2.1e-31 109.2 0.0 2.1 2 0 0 2 2 2 1 REJ domain PLAT PF01477.23 RUS75939.1 - 6e-19 68.7 0.0 1.2e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain GPS PF01825.21 RUS75939.1 - 1.1e-12 48.3 6.7 3.7e-12 46.6 6.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif SPICE PF15678.5 RUS75939.1 - 0.46 9.8 7.0 0.015 14.7 0.8 1.6 2 0 0 2 2 2 0 Centriole duplication and mitotic chromosome congression PKD PF00801.20 RUS75940.1 - 2.9e-10 39.8 2.5 4.2e-09 36.1 2.5 2.1 1 1 0 1 1 1 1 PKD domain Ras PF00071.22 RUS75941.1 - 1.1e-17 64.2 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS75941.1 - 5e-07 30.0 0.0 7.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 RUS75941.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IL4Ra_N PF09238.10 RUS75942.1 - 0.041 14.2 14.4 0.76 10.2 1.1 3.0 2 1 1 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal DUF4043 PF13252.6 RUS75942.1 - 3.6 6.6 9.1 8.6 5.4 1.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4043) SRCR PF00530.18 RUS75942.1 - 6.3 7.4 17.2 10 6.7 1.5 2.7 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain DUF4542 PF15075.6 RUS75943.1 - 2.4e-52 176.9 0.0 3.2e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) LRR_6 PF13516.6 RUS75945.1 - 6.6e-21 72.5 22.3 0.00028 20.7 0.1 10.4 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 RUS75945.1 - 5.5e-15 55.2 7.5 0.00016 22.0 0.0 6.4 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 RUS75945.1 - 3.3e-13 49.3 1.8 4.6e-13 48.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS75945.1 - 5.9e-09 35.6 0.5 2.2e-08 33.8 0.5 2.1 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 RUS75945.1 - 3.6e-06 26.8 20.8 0.34 11.6 0.6 8.6 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 RUS75945.1 - 0.0001 22.0 1.9 8.9 6.2 0.5 5.1 4 2 1 5 5 5 2 Leucine rich repeat F-box_4 PF15966.5 RUS75945.1 - 0.00077 19.3 0.1 0.0037 17.1 0.1 2.2 1 0 0 1 1 1 1 F-box RabGAP-TBC PF00566.18 RUS75946.1 - 1.5e-28 99.9 16.6 9.9e-15 54.8 4.9 3.7 2 1 1 3 3 3 2 Rab-GTPase-TBC domain OmpH PF03938.14 RUS75946.1 - 0.0066 16.8 0.3 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) GrpE PF01025.19 RUS75946.1 - 0.14 11.8 0.4 5.4 6.6 0.2 2.6 2 0 0 2 2 2 0 GrpE Tektin PF03148.14 RUS75946.1 - 0.2 10.4 3.3 0.37 9.5 3.3 1.4 1 0 0 1 1 1 0 Tektin family Macoilin PF09726.9 RUS75946.1 - 7.8 4.9 14.3 4.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Macoilin family Herpes_LMP1 PF05297.11 RUS75947.1 - 0.93 8.6 21.0 1.3 8.2 21.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WH1 PF00568.23 RUS75948.1 - 0.0092 15.9 2.3 39 4.2 0.0 5.8 6 0 0 6 6 6 1 WH1 domain Sfi1 PF08457.10 RUS75948.1 - 0.36 9.3 4.9 2.1 6.8 0.0 3.5 3 1 1 4 4 4 0 Sfi1 spindle body protein DUF4834 PF16118.5 RUS75948.1 - 2.3 9.2 6.1 5 8.1 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) VWC PF00093.18 RUS75949.1 - 3.3e-05 24.1 9.5 4.3e-05 23.7 9.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain PX PF00787.24 RUS75950.1 - 3.8e-16 59.1 0.3 6.7e-16 58.3 0.3 1.4 1 0 0 1 1 1 1 PX domain CP2 PF04516.15 RUS75951.1 - 1.1e-64 217.9 0.0 1.7e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 RUS75951.1 - 6.3e-17 61.2 0.0 1.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS75951.1 - 0.0021 18.4 0.1 0.0055 17.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS75951.1 - 0.0027 17.8 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FLYWCH PF04500.16 RUS75952.1 - 0.0063 16.6 1.6 2.5 8.3 0.0 2.4 2 0 0 2 2 2 2 FLYWCH zinc finger domain NADH-G_4Fe-4S_3 PF10588.9 RUS75952.1 - 0.022 14.3 0.3 8.9 5.9 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region LRV_FeS PF05484.11 RUS75952.1 - 0.083 12.9 1.1 0.083 12.9 1.1 2.4 3 0 0 3 3 3 0 LRV protein FeS4 cluster Sporozoite_P67 PF05642.11 RUS75953.1 - 0.00015 20.0 0.8 0.00017 19.9 0.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 RUS75953.1 - 0.014 15.8 1.0 0.02 15.3 1.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 RUS75953.1 - 0.061 12.1 3.2 0.073 11.8 3.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.12 RUS75953.1 - 0.79 7.6 6.8 0.94 7.4 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 RUS75953.1 - 1.2 7.9 7.6 1.5 7.5 7.6 1.1 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.11 RUS75953.1 - 1.2 9.1 17.5 2.1 8.4 17.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 RUS75953.1 - 1.2 7.3 11.0 1.5 7.0 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF908 PF06012.12 RUS75953.1 - 1.8 7.9 5.8 2.2 7.6 5.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RR_TM4-6 PF06459.12 RUS75953.1 - 2.3 8.0 10.6 2.9 7.6 10.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 RUS75953.1 - 2.8 6.7 4.5 3.2 6.5 4.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2371 PF10177.9 RUS75954.1 - 6.8e-08 32.8 1.3 1.9e-07 31.4 1.3 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) DUF5134 PF17197.4 RUS75954.1 - 0.0025 17.7 4.1 0.0031 17.4 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5134) Neurensin PF14927.6 RUS75954.1 - 0.013 15.2 0.2 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 Neurensin Trp_oprn_chp PF09534.10 RUS75954.1 - 0.035 13.9 0.2 0.046 13.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COQ7 PF03232.13 RUS75954.1 - 0.14 11.9 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF2583 PF10762.9 RUS75954.1 - 0.34 11.4 1.8 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) SseC PF04888.12 RUS75954.1 - 0.45 10.1 3.2 0.57 9.7 3.2 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Apolipoprotein PF01442.18 RUS75955.1 - 0.0017 18.3 4.1 0.005 16.7 4.5 1.5 2 0 0 2 2 1 1 Apolipoprotein A1/A4/E domain CLZ PF16526.5 RUS75955.1 - 0.013 15.9 4.5 0.035 14.5 4.5 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 RUS75955.1 - 0.027 14.9 6.0 1.5 9.3 0.4 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 RUS75955.1 - 0.069 12.2 4.1 0.12 11.5 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BAMBI PF06211.12 RUS75955.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain LMBR1 PF04791.16 RUS75955.1 - 0.14 11.0 2.3 0.19 10.6 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PBECR5 PF18814.1 RUS75955.1 - 0.2 11.6 2.7 0.34 10.8 2.7 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Exonuc_VII_L PF02601.15 RUS75955.1 - 0.23 11.0 2.6 0.48 10.0 2.6 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 RUS75955.1 - 0.33 10.9 6.8 2.9 7.9 0.7 2.4 1 1 1 2 2 2 0 Prefoldin subunit Phasin PF05597.11 RUS75955.1 - 0.39 10.7 2.8 0.91 9.5 1.9 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 RUS75955.1 - 0.63 10.2 7.1 0.46 10.6 4.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.16 RUS75955.1 - 0.73 9.5 5.7 5 6.8 0.8 2.5 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Nup54 PF13874.6 RUS75955.1 - 0.9 9.6 4.5 2.8 8.0 4.6 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1640 PF07798.11 RUS75955.1 - 1 9.4 6.8 1.9 8.5 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ADIP PF11559.8 RUS75955.1 - 1.7 8.7 8.5 0.42 10.7 3.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 RUS75955.1 - 1.9 8.5 7.8 0.75 9.8 0.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 RUS75955.1 - 3.3 8.0 8.3 1.7 9.0 2.5 2.6 2 1 0 3 3 2 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 RUS75955.1 - 3.3 7.8 9.5 6.3 6.9 9.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fzo_mitofusin PF04799.13 RUS75955.1 - 5.8 6.5 5.8 25 4.4 0.7 2.7 2 1 1 3 3 3 0 fzo-like conserved region Anophelin PF10731.9 RUS75958.1 - 0.31 10.9 1.0 0.53 10.2 1.0 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito PHD PF00628.29 RUS75959.1 - 3.3e-11 42.9 20.7 7e-06 25.9 2.4 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 RUS75959.1 - 3e-09 36.3 22.6 1.5e-05 24.4 3.6 2.9 3 0 0 3 3 3 2 PHD-finger LSM_int_assoc PF16605.5 RUS75959.1 - 0.03 14.5 0.8 1 9.5 0.1 2.6 2 0 0 2 2 2 0 LSM-interacting associated unstructured Zn_ribbon_17 PF17120.5 RUS75959.1 - 0.2 11.3 14.6 0.9 9.2 7.2 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 RUS75959.1 - 0.49 10.6 16.6 2.8 8.2 6.4 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Zf_RING PF16744.5 RUS75959.1 - 0.57 10.3 11.6 4.1 7.6 4.6 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger Pox_vIL-18BP PF05566.12 RUS75959.1 - 0.81 9.9 7.4 8.6 6.6 0.7 3.4 2 1 1 3 3 3 0 Orthopoxvirus interleukin 18 binding protein zf-PHD-like PF15446.6 RUS75959.1 - 2.2 7.9 17.1 2.6 7.6 2.6 3.1 2 2 2 4 4 4 0 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 RUS75959.1 - 7 6.6 18.4 2.4 8.1 3.1 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Tudor_2 PF18104.1 RUS75960.1 - 0.049 13.3 0.1 7.3 6.4 0.2 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Mucin PF01456.17 RUS75961.1 - 0.00032 20.7 8.7 0.00046 20.2 8.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SOG2 PF10428.9 RUS75961.1 - 0.37 10.0 2.7 0.46 9.6 2.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Usp PF00582.26 RUS75962.1 - 1.6e-08 35.1 0.0 2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Prominin PF05478.11 RUS75962.1 - 0.013 13.5 0.0 0.015 13.3 0.0 1.0 1 0 0 1 1 1 0 Prominin Myb_DNA-binding PF00249.31 RUS75963.1 - 3.8e-22 78.2 10.3 1.1e-13 51.1 0.1 4.6 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS75963.1 - 1.6e-13 50.7 9.7 8.7e-07 29.1 0.0 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain DUF2678 PF10856.8 RUS75964.1 - 3.4e-29 101.2 3.5 3.7e-29 101.1 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) TatD_DNase PF01026.21 RUS75965.1 - 1.9e-56 191.3 0.0 3.5e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RUS75965.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase ANF_receptor PF01094.28 RUS75966.1 - 2.1e-19 69.8 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS75966.1 - 0.00033 20.4 0.3 0.0014 18.4 0.2 2.0 2 0 0 2 2 2 1 Periplasmic binding protein Shisa PF13908.6 RUS75966.1 - 0.036 14.3 0.0 0.036 14.3 0.0 3.0 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 RUS75966.1 - 0.17 11.7 0.1 0.77 9.6 0.1 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4834 PF16118.5 RUS75966.1 - 2.3 9.3 0.0 2.3 9.3 0.0 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) ANF_receptor PF01094.28 RUS75967.1 - 6.7e-48 163.6 0.0 3.7e-38 131.5 0.0 2.3 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS75967.1 - 1.6e-07 31.3 0.1 1.4e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 Periplasmic binding protein IGFL PF14653.6 RUS75968.1 - 0.0048 16.8 4.8 0.011 15.7 4.8 1.5 1 0 0 1 1 1 1 Insulin growth factor-like family PTPRCAP PF15713.5 RUS75969.1 - 0.0056 17.0 18.7 0.0089 16.3 18.7 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 RUS75969.1 - 0.01 15.3 14.8 0.011 15.2 14.8 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS75969.1 - 0.038 12.5 15.1 0.039 12.4 15.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 RUS75969.1 - 0.074 12.0 2.0 0.084 11.8 2.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 RUS75969.1 - 0.076 11.2 17.2 0.079 11.2 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 RUS75969.1 - 0.17 11.1 3.3 0.21 10.8 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 RUS75969.1 - 0.19 11.0 16.4 0.21 10.9 16.4 1.1 1 0 0 1 1 1 0 BUD22 DUF5523 PF17661.1 RUS75969.1 - 0.27 10.9 14.2 0.35 10.5 14.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Plasmodium_Vir PF05795.11 RUS75969.1 - 0.29 10.5 3.8 0.3 10.4 3.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Connexin PF00029.19 RUS75969.1 - 0.35 10.6 1.1 0.63 9.8 1.1 1.5 1 0 0 1 1 1 0 Connexin PPP4R2 PF09184.11 RUS75969.1 - 0.84 9.2 13.7 0.99 8.9 13.7 1.3 1 0 0 1 1 1 0 PPP4R2 STAC2_u1 PF16664.5 RUS75969.1 - 1.3 9.4 8.9 2.9 8.3 8.9 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RNA_pol_Rpc4 PF05132.14 RUS75969.1 - 1.5 9.3 8.9 2.2 8.7 8.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 RUS75969.1 - 1.9 7.4 19.8 2.5 7.0 19.8 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 RUS75969.1 - 2.2 7.6 24.6 4 6.7 24.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 RUS75969.1 - 2.2 6.5 12.5 3 6.0 12.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 RUS75969.1 - 2.8 6.1 15.3 3.3 5.9 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RUS75969.1 - 2.9 6.6 8.6 3.5 6.3 8.6 1.2 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 RUS75969.1 - 4.8 7.1 11.7 8.1 6.3 11.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RRN3 PF05327.11 RUS75969.1 - 5.2 5.5 9.6 7.1 5.0 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hid1 PF12722.7 RUS75969.1 - 5.4 5.0 9.1 6 4.9 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FGF-BP1 PF06473.12 RUS75969.1 - 5.6 6.7 8.6 8 6.2 8.6 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Merozoite_SPAM PF07133.11 RUS75969.1 - 6.7 6.7 31.0 10 6.1 31.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sulfotransfer_2 PF03567.14 RUS75971.1 - 1.1e-52 179.5 6.6 1.1e-52 179.5 6.6 1.6 2 0 0 2 2 2 1 Sulfotransferase family DUF3099 PF11298.8 RUS75971.1 - 0.16 12.2 0.8 14 5.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) HepII_C PF18675.1 RUS75972.1 - 0.035 14.2 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Heparinase II C-terminal domain CHRD PF07452.12 RUS75972.1 - 0.078 13.9 0.1 19 6.3 0.0 2.7 2 1 0 2 2 2 0 CHRD domain SspH PF08141.12 RUS75972.1 - 3.4 7.9 5.3 0.76 10.0 0.4 2.4 3 0 0 3 3 3 0 Small acid-soluble spore protein H family Med17 PF10156.9 RUS75973.1 - 2.9e-05 23.0 0.8 2.9e-05 23.0 0.8 2.0 1 1 0 2 2 2 1 Subunit 17 of Mediator complex TPR_2 PF07719.17 RUS75974.1 - 4.4e-23 79.5 8.4 0.038 14.1 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 RUS75974.1 - 6.1e-18 63.5 4.4 0.18 12.1 0.2 8.8 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 RUS75974.1 - 2.8e-16 58.5 9.7 0.15 11.9 0.0 9.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 RUS75974.1 - 2.4e-14 53.6 18.5 0.027 15.0 0.0 7.8 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 RUS75974.1 - 3e-13 49.4 10.9 0.26 12.2 0.4 10.3 8 3 4 12 12 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS75974.1 - 7.7e-13 48.5 22.9 0.00024 21.3 2.2 7.6 5 3 3 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RUS75974.1 - 8.2e-12 45.6 0.7 0.065 13.9 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS75974.1 - 1.8e-11 43.6 3.6 0.0047 17.2 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS75974.1 - 1e-08 35.3 1.5 0.75 10.6 0.1 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS75974.1 - 5.5e-08 33.0 14.8 0.069 13.4 0.0 7.8 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS75974.1 - 6e-07 29.5 1.3 0.00032 20.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 RUS75974.1 - 9.9e-07 28.0 0.1 0.018 14.0 0.2 2.7 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 RUS75974.1 - 2.8e-06 26.9 0.4 0.0016 18.1 0.0 4.7 5 0 0 5 5 5 1 TPR repeat TPR_20 PF14561.6 RUS75974.1 - 1.5e-05 25.3 7.0 4 7.8 0.0 6.8 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS75974.1 - 3.2e-05 23.7 8.5 0.034 14.0 1.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS75974.1 - 0.00084 18.6 6.1 1.7 7.8 0.7 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS75974.1 - 0.0016 18.4 10.8 47 4.3 0.5 9.4 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_21 PF09976.9 RUS75974.1 - 0.0019 17.9 2.2 2.7 7.7 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain Tcf25 PF04910.14 RUS75974.1 - 0.051 12.6 1.4 0.16 11.0 0.3 2.3 2 1 1 3 3 3 0 Transcriptional repressor TCF25 FAT PF02259.23 RUS75974.1 - 0.084 12.1 4.4 0.34 10.1 0.7 3.6 4 1 0 4 4 4 0 FAT domain TPR_4 PF07721.14 RUS75974.1 - 1.6 9.6 6.1 84 4.3 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat SHIPPO-rpt PF07004.12 RUS75975.1 - 0.068 14.1 16.9 1.6 9.8 0.9 5.2 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat EF-hand_1 PF00036.32 RUS75976.1 - 4.8e-43 141.5 10.8 5.9e-10 38.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS75976.1 - 2.6e-36 123.9 2.7 1.6e-18 66.9 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS75976.1 - 1.7e-33 114.3 11.2 8.6e-16 57.5 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RUS75976.1 - 1.2e-30 102.7 6.0 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS75976.1 - 1.5e-27 93.8 8.3 7.4e-07 28.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS75976.1 - 7.7e-16 58.2 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS75976.1 - 1.7e-10 40.7 0.4 4.2e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RUS75976.1 - 6.3e-08 32.9 0.0 0.0064 16.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RUS75976.1 - 1.3e-06 29.2 0.0 0.00052 20.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 RUS75976.1 - 1.4e-05 25.0 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RUS75976.1 - 7.1e-05 22.8 0.7 0.0005 20.1 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 RUS75976.1 - 0.00022 21.4 4.2 0.055 13.7 0.4 3.1 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 RUS75976.1 - 0.00048 19.8 1.9 0.00052 19.7 1.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 RUS75976.1 - 0.0011 19.7 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 RUS75976.1 - 0.0016 18.4 0.9 0.53 10.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 RUS75976.1 - 0.0027 18.0 0.6 1.6 9.1 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 RUS75976.1 - 0.0028 18.1 0.0 1.4 9.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 RUS75976.1 - 0.0039 17.1 0.6 0.49 10.4 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 RUS75976.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Poly_export PF02563.16 RUS75976.1 - 0.013 15.8 0.0 0.95 9.7 0.0 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 RUS75976.1 - 0.015 15.2 0.6 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 RUS75976.1 - 0.021 15.0 0.4 0.38 10.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 RUS75976.1 - 0.025 13.8 0.1 2.2 7.4 0.0 2.3 1 1 0 2 2 2 0 Cache domain DUF2267 PF10025.9 RUS75976.1 - 0.033 14.5 0.0 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.14 RUS75976.1 - 0.044 13.4 0.7 0.18 11.4 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 RUS75976.1 - 0.067 13.5 0.1 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain TetR_C_7 PF14246.6 RUS75976.1 - 0.081 13.0 0.1 7.8 6.6 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 RUS75976.1 - 0.12 12.5 0.3 0.24 11.5 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 RUS75976.1 - 0.14 12.6 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 RUS75976.1 - 0.17 12.0 0.3 7.3 6.7 0.0 2.8 3 1 0 3 3 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 RUS75976.1 - 0.23 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 zf-C3HC4_3 PF13920.6 RUS75977.1 - 5.6e-10 38.9 15.7 1.2e-09 37.9 15.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS75977.1 - 0.00076 19.3 14.8 0.00076 19.3 14.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SecE PF00584.20 RUS75977.1 - 8.1 6.5 6.5 23 5.0 6.5 1.7 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex ASC PF00858.24 RUS75978.1 - 2.8e-70 237.5 1.7 4.7e-70 236.8 1.7 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2935 PF11155.8 RUS75979.1 - 0.022 15.1 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) RICH PF05062.12 RUS75979.1 - 0.085 13.2 0.7 1.1 9.6 0.0 2.4 3 0 0 3 3 3 0 RICH domain ASC PF00858.24 RUS75980.1 - 8.2e-12 44.8 0.0 8.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Tape_meas_lam_C PF09718.10 RUS75980.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ASC PF00858.24 RUS75981.1 - 2.9e-19 69.4 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Tape_meas_lam_C PF09718.10 RUS75981.1 - 0.021 14.9 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Raptor_N PF14538.6 RUS75981.1 - 0.075 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain UCH PF00443.29 RUS75981.1 - 0.17 11.4 0.0 0.41 10.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AbiH PF14253.6 RUS75981.1 - 0.18 11.7 2.2 0.39 10.6 1.5 1.6 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Phage_TTP_13 PF16463.5 RUS75982.1 - 0.026 14.1 0.1 0.058 12.9 0.1 1.6 1 1 1 2 2 2 0 Phage tail tube protein family ASC PF00858.24 RUS75983.1 - 1.7e-35 122.8 2.7 2e-35 122.6 2.7 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel YscW PF09619.10 RUS75985.1 - 0.079 13.3 0.9 0.12 12.7 0.9 1.2 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Acyl-ACP_TE PF01643.17 RUS75987.1 - 7.2e-07 28.8 0.3 2.3e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase Orexin_rec2 PF03827.13 RUS75987.1 - 0.14 12.1 1.6 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 Orexin receptor type 2 DUF4303 PF14136.6 RUS75989.1 - 7.1e-06 25.8 9.5 1.1 9.0 0.6 4.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4303) ATG16 PF08614.11 RUS75989.1 - 0.078 13.2 0.0 0.46 10.7 0.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5484 PF17583.2 RUS75989.1 - 0.095 12.4 31.0 58 3.5 0.1 9.3 1 1 9 10 10 10 0 Family of unknown function (DUF5484) Hydrolase_6 PF13344.6 RUS75990.1 - 2.2e-26 91.9 0.0 3.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS75990.1 - 4e-20 71.6 0.0 8.1e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 RUS75990.1 - 8.5e-11 42.3 0.4 1.1e-06 28.8 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS75990.1 - 2.1e-10 41.2 0.1 2.1e-08 34.7 0.1 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RUS75990.1 - 0.0012 18.4 0.0 0.0029 17.2 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 RUS75990.1 - 0.19 11.5 0.0 2.7 7.6 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ssu72 PF04722.13 RUS75991.1 - 0.049 13.2 5.2 1.6 8.3 5.2 2.3 1 1 0 1 1 1 0 Ssu72-like protein DUF5069 PF16798.5 RUS75991.1 - 0.83 9.9 10.3 4.1 7.6 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) MOZART2 PF12926.7 RUS75992.1 - 1.6e-21 75.7 0.0 1.8e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART1 PF12554.8 RUS75992.1 - 0.00061 19.5 0.0 0.00084 19.1 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF2795 PF11387.8 RUS75992.1 - 0.062 13.5 0.2 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) PrgI PF12666.7 RUS75993.1 - 6.7 7.5 7.7 0.88 10.3 0.1 3.0 2 1 1 3 3 3 0 PrgI family protein CUE PF02845.16 RUS75994.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain Cwf_Cwc_15 PF04889.12 RUS75995.1 - 0.023 14.4 5.8 0.035 13.9 5.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ASC PF00858.24 RUS75997.1 - 4.3e-15 55.6 8.2 4.6e-15 55.5 8.2 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel MAM PF00629.23 RUS75998.1 - 3.7e-31 108.2 1.7 2.2e-22 79.7 0.0 2.9 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu DUF3915 PF13054.6 RUS75998.1 - 0.24 11.4 0.3 0.37 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS75998.1 - 1.1 7.5 5.6 1.8 6.7 5.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family MAM PF00629.23 RUS75999.1 - 3.8e-17 62.7 1.9 8e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu R2K_3 PF14243.6 RUS75999.1 - 0.087 12.8 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 MAM PF00629.23 RUS76000.1 - 0.0013 18.6 0.7 0.0027 17.6 0.0 1.8 2 1 0 2 2 2 1 MAM domain, meprin/A5/mu Herpes_gE PF02480.16 RUS76002.1 - 0.002 17.0 0.0 0.0021 16.9 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 RUS76002.1 - 0.079 12.4 0.8 0.14 11.6 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sulfatase PF00884.23 RUS76004.1 - 1.3e-60 205.4 0.2 1.7e-60 205.0 0.2 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 RUS76004.1 - 1.1e-06 28.9 0.0 0.00011 22.4 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 RUS76004.1 - 0.0038 16.9 0.3 0.019 14.6 0.3 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase BPL_C PF02237.17 RUS76005.1 - 0.029 14.3 14.9 1.8e+04 -4.4 14.9 4.7 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain SF3b1 PF08920.10 RUS76005.1 - 0.078 13.5 0.2 3.5 8.2 0.2 2.6 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 DUF4774 PF15999.5 RUS76005.1 - 0.16 11.8 4.7 39 4.2 0.2 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4774) TDH PF03347.13 RUS76006.1 - 0.013 15.1 2.4 4.9 6.7 0.2 2.8 1 1 2 3 3 3 0 Vibrio thermostable direct hemolysin Pox_ATPase-GT PF10640.9 RUS76006.1 - 0.014 14.3 2.6 1.3 7.8 0.3 2.1 1 1 1 2 2 2 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase DDRGK PF09756.9 RUS76006.1 - 2.5 7.6 3.3 13 5.4 0.4 2.2 1 1 1 2 2 2 0 DDRGK domain Lipoprotein_19 PF13617.6 RUS76006.1 - 8.8 6.2 14.2 56 3.6 0.5 5.7 5 2 0 5 5 5 0 YnbE-like lipoprotein SHIPPO-rpt PF07004.12 RUS76007.1 - 7.6e-06 26.6 0.3 0.0059 17.5 0.2 2.5 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat ECR1_N PF14382.6 RUS76007.1 - 0.14 11.9 0.0 4.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region BSD PF03909.17 RUS76008.1 - 1.6e-22 79.2 0.7 7.2e-17 61.1 0.1 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 RUS76008.1 - 1.7e-21 76.3 0.5 1e-20 73.8 0.1 2.4 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain CPL PF08144.11 RUS76008.1 - 0.025 14.9 0.2 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 CPL (NUC119) domain DUF1068 PF06364.12 RUS76008.1 - 0.13 12.1 1.5 0.25 11.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) DUF3452 PF11934.8 RUS76009.1 - 1.2e-49 167.4 0.9 3.8e-49 165.8 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) RB_A PF01858.17 RUS76009.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain zf-RING_2 PF13639.6 RUS76010.1 - 1.3e-12 47.8 7.2 3.3e-12 46.5 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS76010.1 - 3.1e-09 36.5 6.4 6e-09 35.6 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS76010.1 - 2.3e-08 33.7 5.8 4e-08 33.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS76010.1 - 1.2e-07 31.5 2.9 1.9e-07 30.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS76010.1 - 1.7e-07 31.1 2.4 3.6e-07 30.1 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS76010.1 - 2.1e-07 31.1 9.5 5e-06 26.7 9.2 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain CUE PF02845.16 RUS76010.1 - 4.3e-07 29.5 0.1 1e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 CUE domain zf-RING_11 PF17123.5 RUS76010.1 - 1.4e-06 27.9 1.7 1.4e-06 27.9 1.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 RUS76010.1 - 3e-06 27.0 3.4 5.4e-06 26.2 3.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS76010.1 - 5e-06 26.4 3.9 8.5e-06 25.6 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 RUS76010.1 - 8.6e-05 22.1 5.4 0.00021 20.9 5.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RUS76010.1 - 0.0002 21.4 1.8 0.00054 20.0 1.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cue1_U7BR PF18499.1 RUS76010.1 - 0.00053 20.0 0.3 0.0013 18.8 0.3 1.6 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 G2BR PF18442.1 RUS76010.1 - 0.0013 18.3 6.4 0.0029 17.2 6.4 1.6 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) zf-C3HC4_4 PF15227.6 RUS76010.1 - 0.011 15.8 4.7 0.021 15.0 4.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 RUS76010.1 - 0.23 11.6 8.2 0.46 10.6 8.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 RUS76010.1 - 0.63 9.9 2.9 1.8 8.4 2.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RUS76010.1 - 0.74 10.0 5.5 2.4 8.4 5.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 RUS76010.1 - 2 8.5 3.7 4.1 7.5 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger VWA_CoxE PF05762.14 RUS76011.1 - 0.00054 19.4 0.0 0.00093 18.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Latexin PF06907.12 RUS76011.1 - 0.0042 16.6 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Latexin zf-C2H2 PF00096.26 RUS76012.1 - 9.6e-20 69.9 156.6 0.00097 19.5 4.6 18.9 19 0 0 19 19 19 14 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76012.1 - 6.8e-10 38.9 159.3 0.017 15.9 4.0 19.3 19 0 0 19 19 19 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS76012.1 - 5.8e-09 36.0 127.1 0.0034 17.8 0.7 17.8 20 0 0 20 20 20 10 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS76012.1 - 1.7e-07 30.8 9.2 1.5e-05 24.6 1.2 16.5 18 0 0 18 18 18 8 C2H2-type zinc-finger domain zf-met PF12874.7 RUS76012.1 - 0.061 13.7 0.0 0.061 13.7 0.0 12.9 14 0 0 14 14 14 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS76012.1 - 0.075 13.4 108.9 0.55 10.6 0.5 15.2 7 3 8 16 16 16 0 C2H2 type zinc-finger (2 copies) DAD PF02109.16 RUS76013.1 - 7.2e-49 164.7 2.9 7.9e-49 164.5 2.9 1.0 1 0 0 1 1 1 1 DAD family Glyco_hydro_20 PF00728.22 RUS76014.1 - 1.2e-12 47.9 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF4838 PF16126.5 RUS76014.1 - 1.4e-06 27.9 1.2 4.3e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4838) Lectin_C PF00059.21 RUS76015.1 - 3.1e-30 105.1 16.9 1.6e-18 67.4 3.0 2.7 3 0 0 3 3 3 2 Lectin C-type domain ShK PF01549.24 RUS76015.1 - 0.0052 17.3 4.0 0.0052 17.3 4.0 3.2 3 0 0 3 3 3 1 ShK domain-like ApeC PF16977.5 RUS76016.1 - 8.2e-42 143.5 0.8 2.5e-41 141.9 0.8 1.9 1 0 0 1 1 1 1 C-terminal domain of apextrin Kringle PF00051.18 RUS76016.1 - 1.7e-12 47.4 5.5 8.8e-12 45.2 5.5 2.3 1 0 0 1 1 1 1 Kringle domain Astacin PF01400.24 RUS76016.1 - 5.2e-08 32.7 0.1 9e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 RUS76016.1 - 1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 RUS76016.1 - 0.00013 22.4 1.4 0.00013 22.4 1.4 3.3 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) A_deamin PF02137.18 RUS76017.1 - 4.8e-98 328.6 0.3 2.4e-97 326.3 0.3 1.9 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain dCache_3 PF14827.6 RUS76017.1 - 0.093 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase UQ_con PF00179.26 RUS76018.1 - 2.6e-15 56.3 0.0 3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 RUS76019.1 - 5e-67 226.0 0.0 5.9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76019.1 - 1.5e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS76019.1 - 8.9e-07 28.2 0.1 3.1e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 RUS76019.1 - 0.00047 19.6 0.2 0.011 15.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS76019.1 - 0.0018 17.9 0.2 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RUS76019.1 - 0.0097 14.7 0.0 0.035 12.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RUS76019.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 RUS76020.1 - 9.6e-61 204.6 0.1 1.3e-60 204.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 RUS76021.1 - 1.8e-37 128.7 0.1 3.4e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 RUS76021.1 - 1.1e-06 29.2 0.8 1.9e-06 28.4 0.8 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) EXS PF03124.14 RUS76021.1 - 0.0052 16.1 2.6 0.0068 15.8 2.6 1.1 1 0 0 1 1 1 1 EXS family DUF2989 PF11207.8 RUS76021.1 - 0.052 13.3 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) LPG_synthase_TM PF03706.13 RUS76021.1 - 0.084 12.4 4.3 0.13 11.8 4.3 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Ufd2P_core PF10408.9 RUS76022.1 - 7e-62 209.9 0.6 1e-61 209.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core eIF-3c_N PF05470.12 RUS76022.1 - 0.0071 14.7 0.2 0.012 14.0 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Methyltr_RsmB-F PF01189.17 RUS76023.1 - 1.5e-26 93.3 0.0 3.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RUS76023.1 - 0.027 14.6 0.0 0.096 12.8 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 RUS76023.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M13_N PF05649.13 RUS76024.1 - 5.8e-77 259.9 0.8 7.6e-77 259.5 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M13 Plk4_PB2 PF18409.1 RUS76024.1 - 0.1 13.3 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Sugar_tr PF00083.24 RUS76025.1 - 7e-22 77.9 3.7 8.8e-22 77.6 3.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS76025.1 - 7.7e-11 41.5 17.3 9.5e-11 41.2 17.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 RUS76025.1 - 2.4e-05 23.1 5.3 2.4e-05 23.1 5.3 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein Creatinase_N_2 PF16189.5 RUS76026.1 - 7.8e-40 136.6 0.0 1.4e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 RUS76026.1 - 9.1e-35 120.2 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 RUS76026.1 - 1.9e-18 66.3 0.1 5.2e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 RUS76026.1 - 3.2e-11 44.0 0.0 2.4e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Plant_vir_prot PF01307.17 RUS76026.1 - 0.091 13.0 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Plant viral movement protein WSC PF01822.19 RUS76027.1 - 0.0057 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 WSC domain zf-RING_UBOX PF13445.6 RUS76029.1 - 1.6e-08 34.5 7.0 1.6e-08 34.5 7.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS76029.1 - 3.7e-08 33.1 7.5 3.7e-08 33.1 7.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 RUS76029.1 - 7.1e-08 32.5 8.4 7.1e-08 32.5 8.4 4.9 5 0 0 5 5 5 2 B-box zinc finger zf-RING_5 PF14634.6 RUS76029.1 - 2.6e-06 27.3 7.9 2.6e-06 27.3 7.9 4.4 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS76029.1 - 7.8e-06 25.6 4.4 7.8e-06 25.6 4.4 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS76029.1 - 0.00014 22.1 7.0 0.00014 22.1 7.0 4.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 RUS76029.1 - 0.00014 21.9 7.6 0.00014 21.9 7.6 3.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-Sec23_Sec24 PF04810.15 RUS76029.1 - 5.8 7.1 13.4 3.5 7.8 0.0 4.1 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Glyco_hydro_1 PF00232.18 RUS76031.1 - 0 1022.5 2.5 7.5e-165 548.7 6.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 Lipase_GDSL_2 PF13472.6 RUS76031.1 - 6.7e-05 23.4 0.0 0.16 12.3 0.0 3.5 4 0 0 4 4 4 2 GDSL-like Lipase/Acylhydrolase family Ocular_alb PF02101.15 RUS76032.1 - 0.075 11.9 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein Pkinase PF00069.25 RUS76033.1 - 3.9e-61 206.7 0.2 5.1e-61 206.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76033.1 - 4.5e-26 91.7 0.0 9.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS76033.1 - 0.00034 20.0 0.3 0.00077 18.9 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS76033.1 - 0.002 17.0 0.3 1.2 7.9 0.0 2.9 2 1 0 3 3 3 2 Fungal protein kinase FTA2 PF13095.6 RUS76033.1 - 0.053 13.1 3.3 0.66 9.6 0.2 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS76033.1 - 0.087 12.7 0.1 0.37 10.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SAM_decarbox PF01536.16 RUS76034.1 - 4.8e-118 394.2 0.8 5.7e-118 394.0 0.8 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TPR_1 PF00515.28 RUS76035.1 - 1.7e-39 132.0 10.9 1.8e-06 27.5 0.0 11.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76035.1 - 2.1e-35 118.0 9.8 6.4e-05 22.8 0.0 12.1 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 RUS76035.1 - 1.2e-30 105.7 6.5 2.7e-07 30.8 0.0 8.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76035.1 - 2.8e-27 93.5 7.5 2.5e-05 24.6 0.0 11.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76035.1 - 2.7e-26 89.5 13.1 0.013 15.7 0.0 11.7 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 RUS76035.1 - 1.8e-25 87.0 5.6 0.0002 21.1 0.0 10.3 11 1 1 12 12 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 RUS76035.1 - 6.3e-22 77.9 0.0 4.5e-05 23.9 0.0 6.9 4 1 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS76035.1 - 5.5e-21 74.9 0.0 1e-05 26.1 0.0 7.0 5 2 3 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS76035.1 - 4.7e-17 62.0 11.8 5.2e-07 29.8 0.4 5.8 3 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS76035.1 - 1.7e-16 59.5 0.0 0.00056 20.5 0.0 8.5 4 1 5 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76035.1 - 4.7e-15 55.0 0.7 2.1e-05 24.1 0.0 6.2 7 0 0 7 7 6 3 TPR repeat TPR_10 PF13374.6 RUS76035.1 - 1.6e-11 43.7 2.4 0.027 14.4 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS76035.1 - 3.4e-09 36.7 0.0 0.11 12.7 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76035.1 - 3.2e-07 30.3 11.8 2.4 8.7 0.1 8.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 RUS76035.1 - 3.5e-07 30.1 4.4 7.5e-05 22.5 0.3 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 RUS76035.1 - 4.9e-07 29.4 0.2 0.052 12.9 0.0 4.8 4 1 2 6 6 6 2 MalT-like TPR region TPR_15 PF13429.6 RUS76035.1 - 1e-06 28.2 1.8 3.6e-05 23.1 0.2 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 RUS76035.1 - 5.6e-06 26.2 5.4 0.1 12.3 0.2 4.9 3 2 2 5 5 4 2 26S proteasome subunit RPN7 DUF3808 PF10300.9 RUS76035.1 - 2.7e-05 23.1 0.4 2.7e-05 23.1 0.4 3.1 2 1 2 4 4 4 1 Protein of unknown function (DUF3808) PPR PF01535.20 RUS76035.1 - 0.00028 20.9 1.8 3.3 8.1 0.0 6.0 6 0 0 6 6 6 1 PPR repeat DUF4810 PF16068.5 RUS76035.1 - 0.00041 20.8 0.2 2.6 8.7 0.0 4.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4810) Rapsyn_N PF10579.9 RUS76035.1 - 0.00042 20.4 1.4 3.1 8.0 0.1 3.9 4 0 0 4 4 4 1 Rapsyn N-terminal myristoylation and linker region Coatomer_E PF04733.14 RUS76035.1 - 0.0011 18.4 5.3 0.035 13.5 0.0 4.1 3 2 1 5 5 5 1 Coatomer epsilon subunit Sel1 PF08238.12 RUS76035.1 - 0.0013 19.4 4.5 34 5.3 0.0 5.9 5 0 0 5 5 5 0 Sel1 repeat Foie-gras_1 PF11817.8 RUS76035.1 - 0.058 13.0 5.1 5.9 6.4 0.1 4.2 3 2 1 4 4 4 0 Foie gras liver health family 1 YfiO PF13525.6 RUS76035.1 - 0.06 13.1 12.7 0.074 12.8 0.1 4.5 2 2 2 4 4 4 0 Outer membrane lipoprotein Wzy_C_2 PF11846.8 RUS76035.1 - 0.064 13.2 0.1 44 3.9 0.0 4.0 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal PPR_2 PF13041.6 RUS76035.1 - 0.6 10.4 6.9 8.4 6.7 0.0 4.9 5 1 0 5 5 4 0 PPR repeat family MIT PF04212.18 RUS76035.1 - 9.8 6.3 18.4 25 5.0 0.0 6.8 10 0 0 10 10 7 0 MIT (microtubule interacting and transport) domain Gemin7 PF11095.8 RUS76036.1 - 8.7e-23 80.0 0.0 1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) ARA70 PF12489.8 RUS76036.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator CUB PF00431.20 RUS76037.1 - 8.8e-05 22.8 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 CUB domain RhoGAP PF00620.27 RUS76038.1 - 1.3e-40 138.7 0.3 8.6e-40 136.0 0.1 2.2 2 1 0 2 2 2 1 RhoGAP domain FGAR-AT_linker PF18072.1 RUS76038.1 - 0.01 16.3 0.0 0.98 10.0 0.0 3.5 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF3194 PF11419.8 RUS76038.1 - 0.016 15.6 0.4 44 4.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3194) BACK PF07707.15 RUS76038.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch Lectin_C PF00059.21 RUS76040.1 - 3.2e-24 85.7 9.8 5.3e-12 46.4 0.3 2.6 2 0 0 2 2 2 2 Lectin C-type domain Chordopox_A33R PF05966.12 RUS76040.1 - 0.028 13.7 0.7 0.087 12.1 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein fn3 PF00041.21 RUS76041.1 - 0.00031 21.0 0.1 0.032 14.6 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain DEC-1_N PF04625.13 RUS76041.1 - 0.08 11.9 0.5 0.11 11.5 0.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Sulfotransfer_2 PF03567.14 RUS76042.1 - 2.5e-08 34.2 0.2 4.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase family DnaJ PF00226.31 RUS76043.1 - 3.2e-10 40.0 0.3 7.5e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain TM2 PF05154.16 RUS76043.1 - 4.9e-10 39.6 10.9 4.9e-10 39.6 10.9 2.1 2 0 0 2 2 2 1 TM2 domain PAP2 PF01569.21 RUS76043.1 - 0.059 13.1 2.6 0.16 11.7 0.0 2.3 2 1 0 2 2 2 0 PAP2 superfamily ESCRT-II PF05871.12 RUS76044.1 - 5.3e-51 172.6 1.6 6.5e-51 172.3 1.6 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit BESS PF02944.20 RUS76046.1 - 3.1e-07 30.1 1.6 3.1e-07 30.1 1.6 1.9 2 0 0 2 2 2 1 BESS motif Lig_chan-Glu_bd PF10613.9 RUS76047.1 - 7.4e-31 106.7 0.0 1.4e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 RUS76047.1 - 1e-28 100.0 1.2 1.7e-28 99.3 1.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS76047.1 - 4e-22 78.8 0.0 5.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 THF_DHG_CYH_C PF02882.19 RUS76048.1 - 1.4e-52 177.2 4.3 1.9e-52 176.8 4.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RUS76048.1 - 1.3e-35 122.2 0.1 2.2e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 RUS76048.1 - 0.004 17.2 0.4 3.7 7.6 0.1 2.4 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LAP1C PF05609.12 RUS76048.1 - 0.028 13.5 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Glyco_hydro_85 PF03644.13 RUS76049.1 - 7.6e-87 291.5 0.0 1.2e-86 290.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Menin PF05053.13 RUS76050.1 - 1.1 7.6 2.9 1.6 7.0 2.9 1.3 1 0 0 1 1 1 0 Menin RPEL PF02755.15 RUS76051.1 - 4.5e-21 73.8 7.9 1.5e-08 34.0 1.7 3.7 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 RUS76051.1 - 5.8e-13 48.3 0.0 1.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 SAP domain Allexi_40kDa PF05549.11 RUS76051.1 - 4.3 6.8 20.2 9.1 5.7 20.2 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Cullin_binding PF03556.15 RUS76052.1 - 1.2e-31 109.7 0.2 1.7e-31 109.1 0.2 1.2 1 0 0 1 1 1 1 Cullin binding B3 PF02362.21 RUS76052.1 - 0.068 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 B3 DNA binding domain DUF447 PF04289.12 RUS76054.1 - 0.087 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) adh_short PF00106.25 RUS76055.1 - 1.6e-35 122.4 0.1 2.5e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS76055.1 - 1.1e-25 90.6 0.0 1.7e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS76055.1 - 1.9e-07 31.2 0.1 4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RUS76055.1 - 3.2e-06 26.7 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 RUS76055.1 - 1.6e-05 24.5 0.0 0.00043 19.8 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS76055.1 - 0.0034 16.8 0.1 0.06 12.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase HNOB PF07700.15 RUS76055.1 - 0.035 14.0 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Haem-NO-binding AP_endonuc_2 PF01261.24 RUS76056.1 - 1e-36 126.4 0.0 1.4e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fibrinogen_C PF00147.18 RUS76057.1 - 1.1e-39 136.5 8.1 1.6e-39 136.0 8.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Imm19 PF15563.6 RUS76057.1 - 0.024 14.1 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 19 Galactosyl_T PF01762.21 RUS76058.1 - 1.3e-38 132.8 0.0 7.3e-35 120.6 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 RUS76058.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 RUS76059.1 - 2.4e-43 148.2 0.0 3.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS76059.1 - 0.00034 20.1 0.1 0.11 11.9 0.0 2.4 2 1 0 2 2 2 2 Fringe-like NTF2 PF02136.20 RUS76061.1 - 2.8e-32 111.8 0.2 4.2e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 RUS76061.1 - 7.4e-14 51.3 0.4 1.3e-13 50.5 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS76061.1 - 4.6e-05 23.5 0.1 0.0001 22.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif SnoaL_2 PF12680.7 RUS76061.1 - 0.024 15.3 0.3 1.6 9.4 0.0 2.6 2 1 1 3 3 3 0 SnoaL-like domain BTB PF00651.31 RUS76062.1 - 2.7e-38 130.6 4.3 7.7e-18 64.7 0.1 3.2 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 RUS76062.1 - 3.8e-09 37.0 0.0 8.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS76062.1 - 4e-07 29.8 0.0 0.00012 22.2 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RUS76062.1 - 1.9e-06 28.1 0.0 4.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS76062.1 - 1.8e-05 25.2 0.0 5.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BACK PF07707.15 RUS76062.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Ank PF00023.30 RUS76062.1 - 0.0013 19.1 0.0 0.0057 17.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat DUF3342 PF11822.8 RUS76062.1 - 0.0039 17.4 2.1 0.021 15.0 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3342) HTH_DeoR PF08220.12 RUS76062.1 - 0.015 15.0 0.1 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain zf-H2C2_2 PF13465.6 RUS76063.1 - 7.3e-55 181.1 105.2 1.9e-07 31.2 2.3 13.8 14 0 0 14 14 14 12 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76063.1 - 2.3e-34 115.9 127.1 0.00035 20.9 0.8 13.9 14 0 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76063.1 - 3.7e-32 108.2 106.7 0.0017 19.0 1.5 13.5 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS76063.1 - 4.3e-09 36.2 105.6 0.0015 18.4 3.6 12.8 12 1 0 12 12 12 8 C2H2-type zinc finger zf-met PF12874.7 RUS76063.1 - 6.6e-09 35.9 84.8 0.17 12.3 0.2 12.7 12 0 0 12 12 12 7 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS76063.1 - 3.7e-08 33.0 56.6 0.0015 18.2 0.2 11.0 12 0 0 12 12 12 6 zinc-finger C2H2-type BolA PF01722.18 RUS76063.1 - 0.0062 16.8 15.6 0.17 12.2 0.4 5.5 3 1 2 5 5 5 1 BolA-like protein zf-C2H2_jaz PF12171.8 RUS76063.1 - 0.027 14.7 95.3 0.39 11.1 0.2 12.6 13 1 0 13 13 13 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 RUS76063.1 - 0.054 13.7 9.4 86 3.4 0.0 6.6 6 0 0 6 6 6 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 RUS76063.1 - 0.26 11.5 58.9 3.1 8.0 1.1 10.0 6 3 4 10 10 10 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RUS76063.1 - 1.6 9.5 50.0 1.8 9.4 0.8 6.7 1 1 6 7 7 7 0 zinc-ribbon family NOA36 PF06524.12 RUS76065.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 NOA36 protein Gal-bind_lectin PF00337.22 RUS76066.1 - 5.5e-10 38.9 0.0 8.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin GRDP-like PF07173.12 RUS76067.1 - 1.2e-27 97.3 3.8 1.6e-27 96.9 2.6 1.8 1 1 1 2 2 2 1 Glycine-rich domain-containing protein-like COesterase PF00135.28 RUS76068.1 - 1.4e-142 476.2 0.0 1.7e-142 475.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS76068.1 - 9.3e-10 38.7 0.2 2.3e-09 37.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS76068.1 - 0.051 14.2 1.5 0.15 12.6 0.8 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 RUS76068.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 RUS76068.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 RUS76069.1 - 3.7e-25 88.7 15.2 5.7e-25 88.1 15.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS76069.1 - 5.4e-13 48.6 28.4 1.4e-12 47.2 28.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 RUS76070.1 - 7.3e-09 35.2 9.0 2.7e-08 33.3 9.0 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ELMO_CED12 PF04727.13 RUS76070.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.4 1 1 0 1 1 1 0 ELMO/CED-12 family ABC_tran PF00005.27 RUS76071.1 - 3.8e-52 176.4 0.0 1.2e-27 97.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RUS76071.1 - 3.9e-33 115.0 17.3 3.9e-33 115.0 17.3 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RUS76071.1 - 1.9e-20 73.9 0.0 1.9e-07 31.2 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 RUS76071.1 - 3.7e-06 27.6 0.0 0.069 13.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 RUS76071.1 - 1.5e-05 24.6 0.0 0.058 12.8 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS76071.1 - 2.1e-05 25.1 0.7 0.16 12.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 RUS76071.1 - 4.1e-05 23.7 0.0 0.74 10.1 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 RUS76071.1 - 0.00098 18.5 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MukB PF04310.12 RUS76071.1 - 0.0016 18.3 0.8 0.057 13.2 0.3 2.4 2 0 0 2 2 2 1 MukB N-terminal AAA_29 PF13555.6 RUS76071.1 - 0.0023 17.6 1.3 0.27 11.0 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RUS76071.1 - 0.0044 16.8 0.5 3.2 7.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RUS76071.1 - 0.024 14.9 0.8 3 8.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RUS76071.1 - 0.027 14.4 0.2 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 RUS76071.1 - 0.035 13.8 0.0 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 RUS76071.1 - 0.047 13.3 4.0 1.6 8.3 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 RUS76071.1 - 0.062 13.0 2.1 1.2 8.8 0.4 2.6 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 RUS76071.1 - 0.1 12.5 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 RUS76071.1 - 0.32 11.1 1.0 29 4.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 RUS76072.1 - 3.1e-29 102.2 0.1 5.6e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RUS76072.1 - 4.3e-15 55.7 14.8 4.3e-15 55.7 14.8 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RUS76072.1 - 4.2e-09 36.6 0.0 3.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS76072.1 - 0.011 15.2 0.1 4.6 6.6 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 RUS76072.1 - 0.014 14.9 11.6 0.042 13.3 11.6 1.7 1 0 0 1 1 1 0 ABC-2 type transporter ABC2_membrane_2 PF12679.7 RUS76072.1 - 0.015 14.6 4.6 0.031 13.6 4.6 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 RUS76072.1 - 0.02 15.4 0.1 0.044 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS76072.1 - 0.044 13.5 0.3 0.1 12.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.6 RUS76072.1 - 0.044 14.5 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) MukB PF04310.12 RUS76072.1 - 0.046 13.5 0.5 0.15 11.9 0.5 1.7 2 0 0 2 2 2 0 MukB N-terminal SbcCD_C PF13558.6 RUS76072.1 - 0.058 13.6 0.0 0.95 9.7 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 RUS76072.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2189 PF09955.9 RUS76072.1 - 0.16 12.2 4.9 0.16 12.2 2.7 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) AAA_30 PF13604.6 RUS76072.1 - 0.23 11.2 0.9 0.52 10.0 0.8 1.7 1 1 0 1 1 1 0 AAA domain TMEM251 PF15190.6 RUS76073.1 - 1.9e-28 99.0 0.4 2.2e-28 98.8 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 251 PLDc_N PF13396.6 RUS76073.1 - 0.0041 17.0 3.6 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal SIR2 PF02146.17 RUS76074.1 - 3e-58 196.6 0.0 4.3e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family VP4_haemagglut PF00426.18 RUS76075.1 - 0.00048 20.4 0.4 0.65 10.2 0.4 3.0 1 1 0 1 1 1 1 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain zf-C2HC_2 PF13913.6 RUS76075.1 - 0.0023 17.8 14.5 1.8e+02 2.2 0.0 8.5 9 0 0 9 9 9 0 zinc-finger of a C2HC-type WW_like PF17890.1 RUS76075.1 - 0.0063 16.6 25.4 0.68 10.1 0.1 5.1 1 1 4 5 5 5 5 Peptidoglycan hydrolase LytB WW-like domain CNOT1_HEAT PF16418.5 RUS76075.1 - 0.13 12.3 0.0 5.8 7.0 0.0 2.8 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat gerPA PF10676.9 RUS76075.1 - 0.29 11.4 7.2 17 5.7 0.1 3.2 1 1 2 3 3 3 0 Spore germination protein gerPA/gerPF RESP18 PF14948.6 RUS76076.1 - 1.3 9.4 10.0 29 5.0 0.3 3.8 1 1 4 5 5 5 0 RESP18 domain PMP22_Claudin PF00822.20 RUS76077.1 - 1.1e-07 31.8 3.2 1.5e-07 31.5 3.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS76077.1 - 1.3e-06 28.3 6.7 0.00096 19.0 6.7 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.23 RUS76077.1 - 1.2e-05 25.4 6.3 1.9e-05 24.7 6.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain Tweety PF04906.13 RUS76077.1 - 0.027 13.2 0.7 0.039 12.6 0.1 1.5 2 0 0 2 2 2 0 Tweety DUF4293 PF14126.6 RUS76077.1 - 0.07 13.4 0.2 0.16 12.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) TMEM192 PF14802.6 RUS76077.1 - 0.17 11.0 0.4 0.39 9.8 0.1 1.8 2 1 1 3 3 3 0 TMEM192 family DUF4131 PF13567.6 RUS76077.1 - 0.17 11.5 6.0 0.48 10.1 1.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) TMEM51 PF15345.6 RUS76077.1 - 0.23 11.3 0.0 0.31 10.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF202 PF02656.15 RUS76077.1 - 0.54 10.7 13.8 9.2 6.8 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4199 PF13858.6 RUS76077.1 - 1.2 9.6 7.0 0.41 11.0 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1700 PF08006.11 RUS76077.1 - 1.9 8.0 3.8 2.9 7.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Spem1 PF15670.5 RUS76078.1 - 0.042 13.4 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 ABC_transp_aux PF09822.9 RUS76081.1 - 6.4e-07 29.1 0.0 3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 RUS76081.1 - 0.0026 16.6 0.0 0.0095 14.8 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4159 PF13709.6 RUS76081.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) ITAM PF02189.15 RUS76082.1 - 1.9e-13 50.0 56.4 52 4.6 0.1 17.5 18 0 0 18 18 18 0 Immunoreceptor tyrosine-based activation motif YkyA PF10368.9 RUS76082.1 - 0.00097 18.9 36.3 1.8 8.2 5.9 4.8 1 1 4 5 5 5 5 Putative cell-wall binding lipoprotein Ant_C PF05586.11 RUS76082.1 - 0.0025 18.4 24.3 26 5.5 0.9 7.5 1 1 4 5 5 5 0 Anthrax receptor C-terminus region NUC129 PF08157.11 RUS76082.1 - 0.014 15.8 65.4 15 6.0 2.4 10.1 1 1 15 16 16 16 0 NUC129 domain PhzC-PhzF PF02567.16 RUS76082.1 - 0.03 13.8 9.2 7 6.0 2.5 3.6 1 1 3 4 4 4 0 Phenazine biosynthesis-like protein Plasmo_rep PF12135.8 RUS76082.1 - 0.063 12.8 39.3 2.5e+02 1.3 0.0 15.1 17 0 0 17 17 17 0 Plasmodium repeat family 7TMR-DISMED2 PF07696.11 RUS76082.1 - 1.8 8.6 14.3 24 5.0 3.3 3.7 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 TUTF7_u4 PF16631.5 RUS76082.1 - 7 7.3 27.5 1.8e+04 -16.1 27.5 5.7 1 1 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 GNVR PF13807.6 RUS76082.1 - 8 6.5 43.7 93 3.1 0.4 9.6 1 1 13 14 14 14 0 G-rich domain on putative tyrosine kinase DUF1115 PF06544.12 RUS76083.1 - 0.0076 16.4 4.2 0.19 11.8 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1115) Plasmodium_HRP PF05403.11 RUS76083.1 - 0.077 12.8 13.7 0.1 12.4 13.7 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Fanconi_A_N PF15865.5 RUS76083.1 - 0.54 9.6 5.4 7.9 5.8 2.3 2.6 1 1 1 2 2 2 0 Fanconi anaemia group A protein N terminus Crisp PF08562.10 RUS76083.1 - 2.5 8.7 5.5 7.9 7.2 1.1 2.6 1 1 2 3 3 3 0 Crisp ANATO PF01821.18 RUS76083.1 - 3.1 8.7 23.9 32 5.5 1.6 6.2 1 1 4 5 5 5 0 Anaphylotoxin-like domain MIT_LIKE_ACTX PF17556.2 RUS76083.1 - 4.3 8.0 35.4 14 6.4 1.6 5.6 1 1 5 6 6 6 0 MIT-like atracotoxin family Laminin_EGF PF00053.24 RUS76083.1 - 5.2 7.3 19.6 13 6.0 2.0 3.8 1 1 2 3 3 3 0 Laminin EGF domain Utp11 PF03998.13 RUS76084.1 - 6.8e-61 206.3 29.7 7.7e-61 206.1 29.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 RUS76084.1 - 0.062 12.6 0.1 0.062 12.6 0.1 2.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4810 PF16068.5 RUS76084.1 - 0.066 13.8 1.8 0.15 12.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) IMS PF00817.20 RUS76084.1 - 0.55 10.2 3.6 0.92 9.5 3.6 1.6 1 1 0 1 1 1 0 impB/mucB/samB family WD40 PF00400.32 RUS76087.1 - 0.00055 20.7 16.8 0.91 10.5 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 RUS76087.1 - 0.041 13.9 0.0 0.75 9.9 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 RUS76087.1 - 0.045 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 RUS76087.1 - 0.076 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like ZF-HD_dimer PF04770.12 RUS76087.1 - 0.17 12.2 1.8 1.5 9.3 0.8 2.6 2 0 0 2 2 2 0 ZF-HD protein dimerisation region LicD PF04991.13 RUS76088.1 - 5.9e-06 26.6 0.0 3.7e-05 24.0 0.2 2.3 2 1 2 4 4 4 1 LicD family TPT PF03151.16 RUS76089.1 - 2.6e-84 283.0 21.4 3.1e-84 282.7 21.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS76089.1 - 4.9e-16 59.1 26.1 1.6e-11 44.6 8.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Myb_DNA-binding PF00249.31 RUS76090.1 - 3.2e-09 36.8 23.0 0.21 11.8 0.1 6.4 2 1 5 7 7 7 7 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 RUS76090.1 - 2.3e-06 27.8 15.4 2.6 8.4 0.4 5.5 1 1 7 8 8 8 7 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_M64 PF09471.10 RUS76090.1 - 6.8e-06 25.8 6.5 14 5.1 0.1 5.9 1 1 7 8 8 8 2 IgA Peptidase M64 BRCT_3 PF18428.1 RUS76090.1 - 1e-05 25.5 7.3 0.23 11.6 0.8 3.8 1 1 5 6 6 6 6 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.6 RUS76090.1 - 0.00072 19.8 21.0 19 5.6 1.1 7.2 1 1 7 8 8 8 0 Myb-like DNA-binding domain DUF725 PF05267.12 RUS76090.1 - 0.0008 19.4 15.1 0.6 10.1 1.1 3.3 1 1 3 4 4 4 4 Protein of unknown function (DUF725) RE_EcoO109I PF14511.6 RUS76090.1 - 0.0021 17.7 3.2 3.4 7.2 0.3 3.0 1 1 2 3 3 3 3 Type II restriction endonuclease EcoO109I EDS1_EP PF18117.1 RUS76090.1 - 0.042 14.3 8.5 17 5.9 0.2 3.4 1 1 4 5 5 5 0 Enhanced disease susceptibility 1 protein EP domain AAA_lid_5 PF17865.1 RUS76090.1 - 0.071 13.2 1.8 1.8e+02 2.3 0.0 4.0 1 1 6 7 7 7 0 Midasin AAA lid domain AP4E_app_platf PF14807.6 RUS76090.1 - 0.19 12.1 18.0 15 6.0 0.3 4.4 1 1 5 6 6 6 0 Adaptin AP4 complex epsilon appendage platform DUF1539 PF07560.11 RUS76090.1 - 4.6 7.3 12.9 37 4.4 0.8 3.7 1 1 3 4 4 4 0 Domain of Unknown Function (DUF1539) DUF3950 PF13132.6 RUS76090.1 - 8 6.3 15.5 2.5e+02 1.5 0.0 7.2 9 0 0 9 9 9 0 Domain of unknown function (DUF3950) HCV_NS5a PF01506.19 RUS76091.1 - 3e-07 30.1 0.0 1.1e+02 2.8 0.0 8.0 9 0 0 9 9 9 0 Hepatitis C virus non-structural 5a protein membrane anchor MerR_1 PF13411.6 RUS76091.1 - 4.2e-06 26.7 9.0 2.6 8.2 0.1 5.7 4 2 1 6 6 6 2 MerR HTH family regulatory protein DnaB_2 PF07261.11 RUS76091.1 - 6.9e-06 25.7 14.6 1.1 9.1 0.3 5.4 1 1 3 4 4 4 3 Replication initiation and membrane attachment ELYS PF13934.6 RUS76091.1 - 0.00059 19.9 1.7 0.48 10.4 0.3 3.1 1 1 1 2 2 2 2 Nuclear pore complex assembly Suv3_N PF18114.1 RUS76091.1 - 0.0061 16.7 5.6 6.7 6.9 0.3 4.1 1 1 4 5 5 5 1 Suv3 helical N-terminal domain UPF0054 PF02130.17 RUS76091.1 - 0.012 15.4 0.9 3.3 7.5 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized protein family UPF0054 DUF5461 PF17545.2 RUS76091.1 - 0.089 13.1 15.8 2.9 8.3 0.6 4.2 1 1 3 4 4 4 0 Family of unknown function (DUF5461) GerD PF17898.1 RUS76091.1 - 0.089 12.7 2.6 0.13 12.2 1.2 1.7 1 1 1 2 2 2 0 Spore germination GerD central core domain RL PF17797.1 RUS76091.1 - 0.32 11.0 24.6 2.9 7.9 1.2 5.1 1 1 5 6 6 6 0 RL domain Cys_box PF17869.1 RUS76091.1 - 0.33 11.1 12.5 16 5.7 0.9 3.7 1 1 3 4 4 4 0 Anosmin cysteine rich domain DUF4424 PF14415.6 RUS76091.1 - 0.34 10.1 7.8 1.5 8.0 4.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4424) MatP PF06303.12 RUS76091.1 - 0.47 11.0 4.1 38 4.9 1.3 3.2 1 1 2 3 3 3 0 MatP N-terminal domain KGK PF08872.10 RUS76091.1 - 0.71 10.4 9.3 7.6e+02 0.6 9.3 3.3 1 1 0 1 1 1 0 KGK domain DUF3475 PF11961.8 RUS76091.1 - 1.1 9.4 7.5 26 5.0 0.5 3.8 1 1 5 6 6 6 0 Domain of unknown function (DUF3475) rpo132 PF12415.8 RUS76091.1 - 7.8 5.9 16.4 88 2.5 0.1 8.0 11 0 0 11 11 11 0 Poxvirus DNA dependent RNA polymerase UPF0122 PF04297.14 RUS76092.1 - 0.0026 18.0 0.1 1.2 9.4 0.1 2.2 1 1 0 2 2 2 2 Putative helix-turn-helix protein, YlxM / p13 like DUF3683 PF12447.8 RUS76092.1 - 0.0083 16.2 10.4 3.5 7.8 0.7 3.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3683) DcpS PF05652.12 RUS76092.1 - 0.034 15.0 1.4 29 5.6 0.1 3.3 1 1 2 3 3 3 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF364 PF04016.12 RUS76092.1 - 0.12 11.9 0.7 5.4 6.6 0.2 2.5 1 1 1 2 2 2 0 Putative heavy-metal chelation AAA_assoc_C PF09821.9 RUS76092.1 - 0.38 11.3 4.8 21 5.6 1.1 3.0 1 1 2 3 3 3 0 C-terminal AAA-associated domain FliT PF05400.13 RUS76092.1 - 1 10.2 7.9 45 4.9 0.9 4.1 1 1 0 2 2 2 0 Flagellar protein FliT Osw5 PF17062.5 RUS76094.1 - 0.058 13.5 55.3 0.79 9.9 0.3 8.8 1 1 8 9 9 9 0 Outer spore wall 5 Cornifin PF02389.15 RUS76095.1 - 6.8e-08 32.8 10.8 2.7e-07 30.9 10.8 1.8 1 1 0 1 1 1 1 Cornifin (SPRR) family CAML PF14963.6 RUS76095.1 - 6.1 6.9 5.5 7.8 6.5 5.5 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand SAM_adeno_trans PF01887.16 RUS76096.1 - 0.0083 15.6 0.5 0.043 13.2 0.5 1.8 1 1 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Glyco_hydro_26 PF02156.15 RUS76098.1 - 7.6 5.9 5.9 19 4.6 0.1 3.9 1 1 1 3 3 3 0 Glycosyl hydrolase family 26 Gly-zipper_Omp PF13488.6 RUS76099.1 - 0.011 15.7 7.7 0.45 10.5 7.7 2.3 1 1 0 1 1 1 0 Glycine zipper Romo1 PF10247.9 RUS76099.1 - 0.084 13.2 9.5 3.3e+02 1.7 9.5 3.3 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 7tm_1 PF00001.21 RUS76101.1 - 1.2e-36 126.5 16.0 2.1e-36 125.6 16.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS76101.1 - 0.00011 21.7 3.0 0.00026 20.4 3.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv CcmH PF03918.14 RUS76101.1 - 0.86 8.9 2.8 0.73 9.1 0.0 2.3 2 1 1 3 3 3 0 Cytochrome C biogenesis protein XPG_N PF00752.17 RUS76102.1 - 1.9e-20 73.2 0.0 4e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RUS76102.1 - 1.9e-20 73.0 0.1 3.8e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 RUS76102.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing FAM176 PF14851.6 RUS76103.1 - 0.34 10.6 6.7 0.43 10.2 6.2 1.5 1 1 0 1 1 1 0 FAM176 family CLN3 PF02487.17 RUS76103.1 - 0.44 9.5 1.7 0.59 9.1 1.7 1.1 1 0 0 1 1 1 0 CLN3 protein Adap_comp_sub PF00928.21 RUS76104.1 - 6e-34 117.6 0.0 9.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ZapB PF06005.12 RUS76107.1 - 0.096 13.1 1.2 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 RUS76107.1 - 0.17 12.3 2.0 11 6.5 0.2 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 RUS76107.1 - 1.8 8.7 4.4 6.4 7.0 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor TFIIE_beta PF02186.15 RUS76108.1 - 1.8e-09 37.8 17.7 30 5.0 0.1 11.4 1 1 19 20 20 20 1 TFIIE beta subunit core domain DUF1433 PF07252.11 RUS76108.1 - 1e-07 32.1 49.5 4.4 7.6 1.3 9.8 1 1 15 16 16 16 16 Protein of unknown function (DUF1433) Mog1 PF04603.12 RUS76108.1 - 0.0024 18.2 44.8 41 4.5 0.9 11.4 1 1 5 6 6 6 0 Ran-interacting Mog1 protein DUF1428 PF07237.11 RUS76108.1 - 0.014 15.7 52.6 14 6.0 2.0 7.9 1 1 10 11 11 11 0 Protein of unknown function (DUF1428) Imm8 PF15586.6 RUS76108.1 - 5.3 7.1 33.3 69 3.5 0.3 8.2 1 1 19 20 20 20 0 Immunity protein 8 AIG1 PF04548.16 RUS76109.1 - 1e-15 57.6 0.0 1e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Nha1_C PF08619.10 RUS76109.1 - 1.9e-05 24.1 28.8 2.6e-05 23.6 28.8 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Drc1-Sld2 PF11719.8 RUS76109.1 - 0.006 16.2 26.8 0.0077 15.8 26.8 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein SAPS PF04499.15 RUS76109.1 - 3.3 6.4 24.4 3.9 6.1 24.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Endostatin PF06482.11 RUS76109.1 - 5.6 6.3 6.2 8.3 5.8 6.2 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Neur_chan_memb PF02932.16 RUS76109.1 - 7 6.6 9.2 10 6.1 9.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.6 RUS76109.1 - 8.9 5.8 27.6 12 5.4 27.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PSA_CBD PF18341.1 RUS76110.1 - 0.011 15.8 6.3 95 3.1 0.0 5.9 1 1 4 7 7 7 0 PSA endolysin C-terminal cell wall binding domain NUSAP PF16006.5 RUS76111.1 - 9.4e-21 74.8 17.5 5.2e-15 56.0 12.2 4.2 2 1 1 4 4 4 2 Nucleolar and spindle-associated protein Asparaginase PF00710.20 RUS76112.1 - 6.9e-20 71.4 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal DRTGG PF07085.12 RUS76112.1 - 0.0046 16.7 0.1 0.015 15.1 0.1 1.9 2 1 0 2 2 2 1 DRTGG domain PEP_mutase PF13714.6 RUS76116.1 - 7.9e-64 215.4 0.1 9.9e-64 215.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 RUS76116.1 - 0.002 16.7 0.0 0.013 14.0 0.0 2.0 1 1 1 2 2 2 1 Isocitrate lyase family MREG PF15812.5 RUS76116.1 - 0.12 12.7 0.2 0.81 10.0 0.0 2.1 2 0 0 2 2 2 0 Melanoregulin Arf PF00025.21 RUS76117.1 - 2.2e-46 157.5 0.1 2.7e-46 157.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS76117.1 - 3.7e-19 68.9 0.0 4.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS76117.1 - 2.1e-16 60.2 0.0 3.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RUS76117.1 - 7.6e-10 38.5 0.0 9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 RUS76117.1 - 1.5e-08 34.2 0.1 1.2e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RUS76117.1 - 2e-08 33.9 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS76117.1 - 9.4e-06 25.7 0.0 1.8e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RUS76117.1 - 0.03 14.4 0.1 3.9 7.5 0.1 2.2 1 1 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 RUS76117.1 - 0.14 12.0 0.0 4.2 7.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein VirE PF05272.11 RUS76117.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Iso_dh PF00180.20 RUS76118.1 - 1.2e-67 228.5 0.1 1.5e-67 228.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S17 PF00366.20 RUS76118.1 - 0.096 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S17 PRA1 PF03208.19 RUS76119.1 - 1.1e-37 128.8 7.2 1.3e-37 128.6 7.2 1.0 1 0 0 1 1 1 1 PRA1 family protein PhoR PF11808.8 RUS76119.1 - 0.13 12.7 11.8 0.92 10.0 0.8 2.3 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR GPI2 PF06432.11 RUS76119.1 - 0.65 9.4 5.8 0.87 9.0 5.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase SdpI PF13630.6 RUS76119.1 - 5.1 7.3 7.8 8.8 6.5 0.9 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family SIP1 PF04938.12 RUS76120.1 - 1.6e-66 224.1 0.6 1.9e-66 223.9 0.6 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Brix PF04427.18 RUS76122.1 - 4.1e-28 98.8 0.1 6.7e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Brix domain Cadherin-like PF12733.7 RUS76123.1 - 1.9e-07 31.5 0.1 4.3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain TTL PF03133.15 RUS76124.1 - 0.016 14.3 0.1 0.47 9.5 0.0 2.3 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family IF-2 PF11987.8 RUS76126.1 - 9.1e-21 74.0 0.2 2.3e-20 72.7 0.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 RUS76126.1 - 1.8e-14 53.9 0.7 2.4e-09 37.4 0.2 2.4 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 RUS76126.1 - 7e-14 51.5 0.0 2.1e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IL3Ra_N PF18611.1 RUS76127.1 - 1.9e-05 24.6 3.8 0.91 9.6 0.6 4.1 1 1 4 5 5 5 5 IL-3 receptor alpha chain N-terminal domain RAP PF08373.10 RUS76127.1 - 0.29 11.3 17.6 18 5.5 2.2 5.1 1 1 2 3 3 3 0 RAP domain FA_desaturase PF00487.24 RUS76128.1 - 0.052 13.4 6.7 0.098 12.5 6.7 1.4 1 1 0 1 1 1 0 Fatty acid desaturase TcpE PF12648.7 RUS76130.1 - 0.58 10.7 7.8 0.39 11.3 5.1 1.8 2 0 0 2 2 2 0 TcpE family G_glu_transpept PF01019.21 RUS76131.1 - 5.8e-137 457.6 0.0 6.7e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 RUS76132.1 - 1.3e-12 47.3 25.4 1.4e-11 43.9 14.1 2.8 2 2 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS76132.1 - 1.4e-10 40.3 8.2 2.6e-09 36.2 5.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 RUS76132.1 - 0.0008 18.5 2.1 0.0016 17.6 2.1 1.5 1 0 0 1 1 1 1 PUCC protein THAP PF05485.12 RUS76134.1 - 3.9e-23 82.2 7.3 7.9e-13 49.2 0.2 2.5 2 0 0 2 2 2 2 THAP domain HBS1_N PF08938.10 RUS76134.1 - 0.093 13.0 0.5 0.17 12.2 0.5 1.4 1 0 0 1 1 1 0 HBS1 N-terminus DUF3085 PF11284.8 RUS76134.1 - 0.18 12.1 0.1 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) Fibrinogen_C PF00147.18 RUS76135.1 - 2e-128 426.7 26.6 1.7e-48 165.3 4.9 3.0 3 0 0 3 3 3 3 Fibrinogen beta and gamma chains, C-terminal globular domain SH3_1 PF00018.28 RUS76135.1 - 0.23 11.1 11.6 0.46 10.1 0.6 4.4 4 1 1 5 5 5 0 SH3 domain RVT_1 PF00078.27 RUS76136.1 - 7.6e-23 81.2 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YrhC PF14143.6 RUS76136.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 YrhC-like protein EF-hand_7 PF13499.6 RUS76137.1 - 1.7e-13 50.8 3.6 4.2e-10 39.9 0.4 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS76137.1 - 1.8e-11 43.0 4.6 0.00025 20.7 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RUS76137.1 - 3.3e-11 41.9 6.4 0.0022 17.4 0.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS76137.1 - 2.1e-07 30.7 5.2 0.05 13.4 0.2 4.1 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS76137.1 - 0.00026 20.3 3.9 1.1 8.8 0.0 3.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 RUS76137.1 - 0.037 14.3 3.4 0.039 14.3 0.7 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RT_RNaseH_2 PF17919.1 RUS76138.1 - 3.3e-34 116.9 0.0 5.5e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS76138.1 - 1.2e-31 109.1 0.0 2e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS76138.1 - 1.5e-22 80.2 0.1 2.5e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 RUS76139.1 - 6.4e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain TAL_FSA PF00923.19 RUS76140.1 - 3.3e-99 331.9 0.2 3.7e-99 331.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Rootletin PF15035.6 RUS76140.1 - 0.057 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HLH PF00010.26 RUS76141.1 - 1.7e-17 63.1 1.6 1.7e-17 63.1 1.6 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain MAGI_u5 PF16666.5 RUS76141.1 - 0.021 15.0 1.9 0.14 12.3 0.4 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI Dzip-like_N PF13815.6 RUS76141.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ATG16 PF08614.11 RUS76142.1 - 2e-05 24.9 3.4 3.4e-05 24.2 3.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 RUS76142.1 - 0.00025 21.4 1.1 0.00034 21.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DUF4407 PF14362.6 RUS76142.1 - 0.0004 19.8 2.1 0.0006 19.3 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF5082 PF16888.5 RUS76142.1 - 0.00064 20.0 2.7 0.034 14.4 2.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Fez1 PF06818.15 RUS76142.1 - 0.0016 18.9 1.1 0.0022 18.5 1.1 1.2 1 0 0 1 1 1 1 Fez1 COG5 PF10392.9 RUS76142.1 - 0.0019 18.4 4.1 0.11 12.7 0.2 2.1 1 1 1 2 2 2 1 Golgi transport complex subunit 5 End3 PF12761.7 RUS76142.1 - 0.0019 18.4 4.0 0.015 15.4 0.2 2.2 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Rac1 PF09632.10 RUS76142.1 - 0.0021 17.3 0.4 0.0025 17.1 0.4 1.0 1 0 0 1 1 1 1 Rac1-binding domain APG6_N PF17675.1 RUS76142.1 - 0.004 17.7 3.4 0.0062 17.1 3.4 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Lebercilin PF15619.6 RUS76142.1 - 0.0045 16.7 6.5 0.0058 16.3 6.1 1.3 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 RUS76142.1 - 0.0053 16.8 12.5 0.04 14.0 12.1 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 RUS76142.1 - 0.0054 17.1 0.6 0.0069 16.7 0.6 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein LPP PF04728.13 RUS76142.1 - 0.0082 16.5 0.9 0.23 11.9 0.5 2.4 2 0 0 2 2 2 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 RUS76142.1 - 0.0091 16.0 2.9 0.061 13.4 1.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 RUS76142.1 - 0.011 15.8 7.8 0.82 9.8 6.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 RUS76142.1 - 0.011 14.8 3.6 0.023 13.8 3.7 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 RUS76142.1 - 0.012 15.8 3.0 0.016 15.4 3.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 RUS76142.1 - 0.012 15.4 5.6 0.017 14.9 5.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 RUS76142.1 - 0.013 13.1 1.1 0.016 12.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 RUS76142.1 - 0.013 14.4 1.2 0.02 13.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CALCOCO1 PF07888.11 RUS76142.1 - 0.015 14.2 7.3 0.02 13.8 7.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 RUS76142.1 - 0.016 15.3 9.7 0.076 13.1 8.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.16 RUS76142.1 - 0.021 15.0 2.9 0.041 14.1 2.8 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein Muted PF14942.6 RUS76142.1 - 0.022 15.1 0.8 0.035 14.5 0.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 RUS76142.1 - 0.028 13.3 6.5 0.043 12.7 6.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 RUS76142.1 - 0.029 13.9 4.8 0.051 13.0 4.4 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 AIP3 PF03915.13 RUS76142.1 - 0.032 13.3 1.2 0.043 12.9 1.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Filament PF00038.21 RUS76142.1 - 0.034 13.7 3.5 0.048 13.2 3.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF2203 PF09969.9 RUS76142.1 - 0.041 14.6 0.3 0.058 14.1 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Macoilin PF09726.9 RUS76142.1 - 0.048 12.2 1.9 0.063 11.8 1.9 1.0 1 0 0 1 1 1 0 Macoilin family CLZ PF16526.5 RUS76142.1 - 0.05 14.0 3.8 0.42 11.0 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 RUS76142.1 - 0.054 13.8 2.6 0.12 12.8 2.7 1.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IFT57 PF10498.9 RUS76142.1 - 0.059 12.3 2.1 0.08 11.9 2.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 YscO PF07321.12 RUS76142.1 - 0.06 13.3 3.0 0.11 12.4 2.7 1.5 1 1 0 1 1 1 0 Type III secretion protein YscO Bacillus_HBL PF05791.11 RUS76142.1 - 0.074 12.9 5.5 0.15 11.8 5.5 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.22 RUS76142.1 - 0.082 13.2 2.5 0.21 11.9 2.2 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 RUS76142.1 - 0.084 13.1 3.3 0.12 12.6 3.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 RUS76142.1 - 0.09 12.9 2.4 0.68 10.0 1.6 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.13 RUS76142.1 - 0.13 12.8 2.3 1.5 9.3 0.1 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.8 RUS76142.1 - 0.13 11.5 4.6 0.22 10.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 RUS76142.1 - 0.15 10.7 0.2 0.17 10.4 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 RUS76142.1 - 0.15 12.1 8.4 0.31 11.1 8.4 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 RUS76142.1 - 0.15 12.3 7.3 2.8 8.2 0.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TEX13 PF15186.6 RUS76142.1 - 0.16 11.7 4.5 0.2 11.3 2.0 1.9 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family HIP1_clath_bdg PF16515.5 RUS76142.1 - 0.16 12.6 7.8 1.4 9.5 2.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 RUS76142.1 - 0.16 10.5 1.6 0.21 10.1 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 RUS76142.1 - 0.17 12.5 4.5 7 7.3 1.0 2.5 1 1 1 2 2 2 0 SlyX DUF4618 PF15397.6 RUS76142.1 - 0.2 11.0 6.6 0.66 9.3 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Cluap1 PF10234.9 RUS76142.1 - 0.22 10.9 6.1 0.78 9.1 6.2 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 CENP-H PF05837.12 RUS76142.1 - 0.24 11.8 5.2 0.34 11.4 5.2 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) WXG100 PF06013.12 RUS76142.1 - 0.25 11.6 2.3 8.3 6.7 0.3 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ADIP PF11559.8 RUS76142.1 - 0.28 11.3 9.1 0.93 9.6 8.7 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1043 PF06295.12 RUS76142.1 - 0.29 11.2 3.0 0.53 10.3 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Lectin_N PF03954.14 RUS76142.1 - 0.33 10.7 6.9 0.59 9.9 0.4 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TMF_DNA_bd PF12329.8 RUS76142.1 - 0.58 10.2 7.5 1.3 9.1 2.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 RUS76142.1 - 0.63 10.5 3.3 15 6.1 3.3 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.5 RUS76142.1 - 0.91 10.5 7.3 7.1 7.6 7.1 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 RUS76142.1 - 1 9.8 3.2 53 4.3 0.0 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RUS76142.1 - 7.5 6.9 7.4 80 3.6 1.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc24 PF08286.11 RUS76142.1 - 7.9 6.8 7.4 39 4.6 0.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Lectin_C PF00059.21 RUS76143.1 - 9.3e-11 42.4 0.6 1.7e-09 38.3 0.6 2.4 1 1 0 1 1 1 1 Lectin C-type domain MAM PF00629.23 RUS76143.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu Prok-RING_2 PF14445.6 RUS76143.1 - 0.86 9.8 4.4 0.3 11.3 0.5 2.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 MIF PF01187.18 RUS76144.1 - 7.1e-08 32.7 0.0 9.1e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF1904 PF08921.11 RUS76144.1 - 0.00031 21.0 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) Tautomerase PF01361.21 RUS76144.1 - 0.0055 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Tautomerase enzyme Trypan_PARP PF05887.11 RUS76146.1 - 0.0072 16.3 5.2 0.0072 16.3 5.2 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 RUS76146.1 - 0.29 10.3 0.7 0.92 8.6 1.2 1.5 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 NAD_binding_2 PF03446.15 RUS76147.1 - 8e-40 136.6 0.1 1.2e-39 136.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PWWP PF00855.17 RUS76147.1 - 5.3e-17 62.0 0.8 1.2e-16 60.9 0.8 1.6 1 0 0 1 1 1 1 PWWP domain NAD_binding_11 PF14833.6 RUS76147.1 - 1.1e-14 54.7 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 RUS76147.1 - 8.7e-09 35.9 0.3 3.6e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 RUS76147.1 - 7.5e-05 22.4 0.1 0.00024 20.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 RUS76147.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 RUS76147.1 - 0.0056 16.6 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RUS76147.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 RUS76147.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RUS76147.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain LRR_8 PF13855.6 RUS76148.1 - 2.6e-47 158.4 40.7 1.3e-15 56.9 1.4 7.3 5 2 3 8 8 7 6 Leucine rich repeat LRR_4 PF12799.7 RUS76148.1 - 1.4e-24 85.7 37.2 4.1e-07 30.2 0.2 8.8 5 2 1 8 8 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS76148.1 - 4.2e-13 49.4 0.9 2.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS76148.1 - 1e-09 37.6 34.4 0.11 12.6 0.1 11.8 11 1 1 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 RUS76148.1 - 1.1e-07 31.4 38.2 1.1 10.0 0.2 12.3 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 RUS76148.1 - 2.7e-07 30.3 3.3 0.0075 15.8 0.1 3.9 2 1 3 5 5 5 3 Leucine-rich repeat V-set PF07686.17 RUS76148.1 - 0.00049 20.2 0.2 0.071 13.3 0.2 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain SieB PF14163.6 RUS76148.1 - 0.001 18.6 1.1 0.0024 17.4 1.1 1.5 1 0 0 1 1 1 1 Super-infection exclusion protein B Ig_3 PF13927.6 RUS76148.1 - 0.0019 18.8 0.1 0.014 15.9 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS76148.1 - 0.02 15.1 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Apolipoprotein PF01442.18 RUS76148.1 - 0.027 14.3 3.4 0.045 13.6 3.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SUIM_assoc PF16619.5 RUS76148.1 - 0.044 13.8 0.1 0.23 11.5 0.1 2.3 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 I-set PF07679.16 RUS76148.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF883 PF05957.13 RUS76148.1 - 0.23 12.1 3.8 3.3 8.4 0.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Innexin PF00876.18 RUS76148.1 - 0.71 9.1 4.5 0.33 10.2 1.7 1.7 1 1 1 2 2 2 0 Innexin LRRNT PF01462.18 RUS76148.1 - 8.6 6.1 10.0 1.2 8.9 3.6 2.9 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain CAF1 PF04857.20 RUS76149.1 - 1.1e-20 74.0 2.8 2e-12 46.9 0.0 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease ALG11_N PF15924.5 RUS76150.1 - 1.1e-92 309.9 0.4 5.3e-92 307.6 0.1 2.1 1 1 1 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RUS76150.1 - 1.2e-25 90.0 0.0 2.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RUS76150.1 - 1e-13 51.9 0.0 5.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RUS76150.1 - 0.0064 16.5 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 RUS76150.1 - 0.044 14.2 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 START PF01852.19 RUS76151.1 - 4.3e-28 98.2 0.0 5.1e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 RUS76151.1 - 0.0037 17.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) ZZ PF00569.17 RUS76152.1 - 1.4e-13 50.4 5.2 8.8e-13 47.8 6.3 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type PB1 PF00564.24 RUS76152.1 - 7e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Spt20 PF12090.8 RUS76152.1 - 0.0014 18.3 14.0 0.0014 18.3 14.0 2.4 3 0 0 3 3 3 1 Spt20 family Plasmodium_Vir PF05795.11 RUS76152.1 - 0.0043 16.5 0.2 0.0043 16.5 0.2 2.1 2 0 0 2 2 2 1 Plasmodium vivax Vir protein EPL1 PF10513.9 RUS76152.1 - 0.0083 16.5 0.2 0.0083 16.5 0.2 2.5 3 0 0 3 3 3 1 Enhancer of polycomb-like DUF3391 PF11871.8 RUS76152.1 - 0.018 15.6 4.0 0.018 15.6 4.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) C1_2 PF03107.16 RUS76152.1 - 0.02 15.2 5.8 0.037 14.4 5.8 1.4 1 0 0 1 1 1 0 C1 domain SpoIIP PF07454.11 RUS76152.1 - 0.65 9.4 15.2 0.067 12.6 3.7 3.0 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 RUS76152.1 - 0.83 10.3 26.2 0.23 12.1 10.8 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 RUS76152.1 - 1.5 7.8 7.0 0.75 8.8 2.3 2.2 2 0 0 2 2 2 0 Solute carrier family 12 Band_3_cyto PF07565.13 RUS76152.1 - 6.8 6.4 6.7 0.73 9.6 0.9 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Suf PF05843.14 RUS76152.1 - 7.6 6.4 14.5 1.6 8.6 8.4 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 RUS76152.1 - 9.5 4.8 8.0 0.4 9.3 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Rxt3 PF08642.10 RUS76152.1 - 9.7 7.0 9.2 9.6 7.0 1.4 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 PB1 PF00564.24 RUS76153.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SR-25 PF10500.9 RUS76153.1 - 0.00044 19.9 23.5 0.00044 19.9 23.5 4.0 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein PDEase_I_N PF08499.12 RUS76153.1 - 0.57 10.1 3.7 8 6.4 0.1 3.1 3 0 0 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal RAP1 PF07218.11 RUS76153.1 - 2.2 6.5 6.9 3.4 5.8 6.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 RUS76153.1 - 3 6.3 14.8 0.57 8.7 11.4 1.4 2 0 0 2 2 2 0 Macoilin family DHHW PF14286.6 RUS76153.1 - 5.5 6.2 7.8 0.17 11.1 0.8 1.8 2 0 0 2 2 2 0 DHHW protein Cadherin PF00028.17 RUS76154.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 Cadherin domain Cadherin PF00028.17 RUS76155.1 - 1.5e-08 34.9 3.7 0.0089 16.5 0.1 3.4 3 1 0 3 3 3 3 Cadherin domain EIIBC-GUT_C PF07663.11 RUS76155.1 - 0.13 12.5 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus SSP160 PF06933.11 RUS76156.1 - 7.7e-05 21.1 10.1 9.3e-05 20.8 10.1 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 RUS76156.1 - 0.0012 19.3 1.7 0.0017 18.8 1.7 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 RUS76156.1 - 0.0033 17.3 0.7 0.0046 16.9 0.7 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 RUS76156.1 - 0.011 15.1 1.7 0.016 14.6 1.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF3439 PF11921.8 RUS76156.1 - 0.014 15.4 14.7 0.021 14.8 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 RUS76156.1 - 0.025 14.6 21.4 0.049 13.6 21.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Viral_Beta_CD PF04530.12 RUS76156.1 - 0.12 12.7 1.0 0.18 12.1 1.0 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family RIFIN PF02009.16 RUS76156.1 - 0.54 10.1 3.0 0.27 11.1 1.4 1.3 1 1 0 1 1 1 0 Rifin DUF4083 PF13314.6 RUS76156.1 - 1.5 8.8 5.7 2.4 8.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MFS_1 PF07690.16 RUS76157.1 - 2.5e-21 76.0 17.9 2.5e-21 76.0 17.9 2.5 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS76157.1 - 7.9e-08 31.6 6.6 9.2e-05 21.5 0.1 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Ribosomal_L5_C PF00673.21 RUS76158.1 - 2.2e-22 79.0 0.0 3.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 RUS76158.1 - 1.9e-21 76.2 0.1 9.5e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 RUS76158.1 - 0.014 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Imm48 PF15574.6 RUS76159.1 - 0.097 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 48 Pkinase PF00069.25 RUS76160.1 - 1.2e-50 172.3 0.4 1.6e-50 172.0 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76160.1 - 2.6e-22 79.4 1.7 8.7e-22 77.6 0.2 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Macoilin PF09726.9 RUS76160.1 - 1.1 7.7 6.8 1.6 7.2 6.8 1.2 1 0 0 1 1 1 0 Macoilin family Herpes_BLLF1 PF05109.13 RUS76163.1 - 0.0011 17.1 9.6 0.0011 17.1 9.6 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) FAP PF07174.11 RUS76163.1 - 2.1 7.7 13.1 2.3 7.6 13.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CCDC74_C PF14917.6 RUS76164.1 - 0.053 14.0 0.2 0.082 13.4 0.2 1.4 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal Claudin_2 PF13903.6 RUS76166.1 - 0.22 11.2 7.0 0.48 10.1 6.4 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS76166.1 - 0.24 11.3 7.6 0.67 9.9 7.6 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SNARE_assoc PF09335.11 RUS76166.1 - 0.99 9.9 7.6 31 5.1 3.5 3.0 2 1 1 3 3 3 0 SNARE associated Golgi protein Glyco_transf_11 PF01531.16 RUS76168.1 - 5.7e-10 38.9 0.0 6.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Peptidase_M3_N PF08439.10 RUS76168.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F MRNIP PF15749.5 RUS76169.1 - 8e-28 97.3 3.6 1.1e-27 96.8 3.6 1.5 1 1 0 1 1 1 1 MRN-interacting protein Zn-ribbon_8 PF09723.10 RUS76169.1 - 0.021 14.9 0.8 0.052 13.7 0.2 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 RUS76169.1 - 0.034 14.2 3.0 0.15 12.1 3.0 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger adh_short PF00106.25 RUS76170.1 - 6.8e-46 156.2 0.0 9.9e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS76170.1 - 5e-31 108.1 0.0 6.4e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS76170.1 - 1.8e-07 31.3 0.1 2.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 RUS76170.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 RUS76171.1 - 4.9e-77 254.6 18.0 1.7e-15 57.4 0.3 8.4 5 1 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS76171.1 - 6.2e-68 224.4 20.1 2.7e-10 40.6 0.0 10.9 6 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 RUS76171.1 - 1.8e-62 205.2 23.9 7.6e-07 29.3 0.1 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 RUS76171.1 - 1.9e-56 187.4 28.2 1.5e-07 31.5 0.3 12.2 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS76171.1 - 2.8e-55 177.8 24.2 2.8e-05 24.1 0.0 14.9 16 0 0 16 16 16 10 Ankyrin repeat Ion_trans PF00520.31 RUS76171.1 - 4.1e-16 58.9 24.7 4.1e-16 58.9 24.7 1.5 1 1 1 2 2 2 1 Ion transport protein Snapin_Pallidin PF14712.6 RUS76171.1 - 0.17 12.3 3.7 0.64 10.5 3.7 1.9 1 0 0 1 1 1 0 Snapin/Pallidin MAP17 PF15807.5 RUS76171.1 - 4.7 7.5 8.3 0.27 11.5 0.8 2.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SLX9 PF15341.6 RUS76171.1 - 6.3 7.2 8.6 20 5.6 1.6 2.8 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 CCAP PF11105.8 RUS76174.1 - 0.00093 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a 7tm_2 PF00002.24 RUS76176.1 - 4.3e-17 62.2 0.7 5.6e-17 61.8 0.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 RUS76177.1 - 1.4e-27 96.6 7.5 2.5e-27 95.7 7.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS76177.1 - 1.1e-05 25.8 6.5 8.9e-05 22.9 6.5 2.5 1 1 0 1 1 1 1 GPCR proteolysis site, GPS, motif Lectin_C PF00059.21 RUS76177.1 - 0.00036 21.2 0.0 0.00036 21.2 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain Reeler PF02014.16 RUS76178.1 - 2e-16 60.9 0.0 2.5e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Reeler domain ASH PF15780.5 RUS76179.1 - 0.00016 21.8 0.0 0.64 10.3 0.0 2.7 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RUS76179.1 - 0.0062 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 RUS76179.1 - 0.041 13.7 0.2 0.57 10.1 0.0 2.5 3 0 0 3 3 3 0 MSP (Major sperm protein) domain PqqA PF08042.11 RUS76179.1 - 0.053 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 PqqA family Pep_M12B_propep PF01562.19 RUS76180.1 - 3.1e-05 24.2 0.1 4.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Endonuclea_NS_2 PF13930.6 RUS76180.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Reprolysin PF01421.19 RUS76181.1 - 7.7e-55 185.9 0.1 1.6e-54 184.9 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 RUS76181.1 - 2.8e-28 98.7 5.3 2.8e-28 98.7 5.3 3.3 3 0 0 3 3 2 1 ADAM cysteine-rich Disintegrin PF00200.23 RUS76181.1 - 2e-18 67.0 30.2 2e-18 67.0 30.2 4.2 4 0 0 4 4 3 1 Disintegrin Reprolysin_5 PF13688.6 RUS76181.1 - 5.8e-17 62.5 2.0 5.8e-17 62.5 2.0 2.3 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS76181.1 - 2e-10 41.2 1.1 5.7e-10 39.8 1.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS76181.1 - 5.1e-10 39.6 1.5 1.4e-09 38.1 1.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS76181.1 - 3.7e-06 26.7 0.3 3.7e-06 26.7 0.3 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 RUS76181.1 - 0.0043 17.4 11.6 0.0043 17.4 11.6 5.3 5 1 1 6 6 3 1 EGF-like domain TMEM154 PF15102.6 RUS76181.1 - 0.039 13.9 1.4 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family DUF5047 PF16466.5 RUS76181.1 - 0.1 13.0 1.2 0.25 11.7 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5047) Peptidase_M54 PF07998.11 RUS76181.1 - 0.19 11.7 0.6 0.44 10.5 0.6 1.5 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 RUS76181.1 - 0.31 10.0 3.9 0.11 11.4 1.1 1.6 2 0 0 2 2 2 0 Peptidase M66 ABC2_membrane PF01061.24 RUS76182.1 - 4.6e-40 137.3 24.9 6.7e-40 136.7 24.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RUS76182.1 - 3.1e-21 76.3 0.0 6.8e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 RUS76182.1 - 0.00019 21.4 0.2 0.00038 20.4 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 RUS76182.1 - 0.0003 20.0 9.6 0.0003 20.0 9.6 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 RUS76182.1 - 0.00096 18.6 0.0 0.028 13.9 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RUS76182.1 - 0.0019 17.9 0.1 0.0054 16.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 RUS76182.1 - 0.0033 17.3 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RUS76182.1 - 0.0077 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 RUS76182.1 - 0.014 15.7 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 RUS76182.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RUS76182.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS76182.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 RUS76182.1 - 0.086 11.8 0.1 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 RUS76182.1 - 0.096 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 RUS76182.1 - 0.15 12.5 0.3 0.57 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RUS76182.1 - 0.2 11.7 0.2 0.36 10.9 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_2 PF12679.7 RUS76182.1 - 0.89 8.8 15.4 0.0087 15.4 5.4 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein GCP_C_terminal PF04130.13 RUS76183.1 - 4.7e-59 200.4 12.3 4.4e-58 197.2 11.4 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RUS76183.1 - 5.1e-56 190.5 1.6 1.8e-54 185.5 0.0 2.1 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal UPF0524 PF15823.5 RUS76183.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Thr_synth_N PF14821.6 RUS76184.1 - 5.6e-26 90.6 0.0 3.1e-25 88.2 0.0 2.3 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.25 RUS76184.1 - 1.8e-15 57.2 0.0 3.7e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tmemb_9 PF05434.11 RUS76186.1 - 0.011 15.6 1.1 0.043 13.7 1.1 2.0 1 0 0 1 1 1 0 TMEM9 Cnd2 PF05786.14 RUS76187.1 - 8.9e-123 411.5 18.2 1.6e-122 410.7 18.2 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 RUS76187.1 - 0.013 15.7 0.0 0.05 13.8 0.0 2.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4665 PF15679.5 RUS76187.1 - 0.11 13.2 0.2 0.11 13.2 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) ABC_tran PF00005.27 RUS76188.1 - 4.1e-17 63.0 0.0 6.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS76188.1 - 4.3e-06 26.3 0.0 5.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain 7TM_GPCR_Srx PF10328.9 RUS76189.1 - 0.00074 19.2 19.3 0.0011 18.7 19.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TNFR_c6 PF00020.18 RUS76190.1 - 3.1e-07 30.7 21.0 1.7e-05 25.1 8.2 3.7 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS76190.1 - 0.0017 18.1 0.9 0.0017 18.1 0.9 3.1 2 1 0 2 2 2 2 Putative ephrin-receptor like DUF4690 PF15756.5 RUS76190.1 - 0.11 13.1 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage NCD3G PF07562.14 RUS76190.1 - 1.3 9.0 17.5 1.7 8.7 1.6 2.9 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR EpuA PF11772.8 RUS76190.1 - 1.7 8.4 6.3 5.4 6.8 5.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta VWD PF00094.25 RUS76191.1 - 2.1e-14 54.1 1.7 3.9e-14 53.2 1.7 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 RUS76191.1 - 7.3e-12 45.5 2.4 7.3e-12 45.5 2.4 3.4 4 0 0 4 4 4 1 C8 domain ShK PF01549.24 RUS76191.1 - 8e-06 26.3 8.2 8e-06 26.3 8.2 5.3 7 1 0 7 7 7 1 ShK domain-like TIL PF01826.17 RUS76191.1 - 0.018 15.2 6.9 0.018 15.2 6.9 4.7 4 0 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain Ribosomal_L17 PF01196.19 RUS76192.1 - 2.7e-14 53.8 0.0 5.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 MAGE_N PF12440.8 RUS76192.1 - 1.8 9.3 13.7 2.6 8.8 13.7 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal TSP_1 PF00090.19 RUS76193.1 - 5e-24 84.3 27.3 5.8e-13 48.8 12.6 2.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain Calpain_III PF01067.22 RUS76193.1 - 2.3 8.5 7.2 6.1 7.1 0.5 2.1 2 0 0 2 2 2 0 Calpain large subunit, domain III zf-H2C2_2 PF13465.6 RUS76194.1 - 2.9e-26 90.7 49.9 6.8e-08 32.6 1.2 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76194.1 - 6.9e-25 86.1 51.1 1.5e-05 25.2 2.3 7.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76194.1 - 9.9e-12 44.7 62.0 0.0055 17.4 1.2 7.7 9 0 0 9 9 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS76194.1 - 0.00013 21.8 50.5 0.11 12.6 1.7 7.3 6 2 0 6 6 6 4 C2H2-type zinc finger zf_UBZ PF18439.1 RUS76194.1 - 0.0056 16.3 15.4 0.75 9.4 0.1 6.3 6 0 0 6 6 6 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 RUS76194.1 - 0.0067 16.7 0.8 0.13 12.6 0.1 6.4 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS76194.1 - 0.014 15.8 42.1 0.25 11.8 0.7 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type XPA_N PF01286.18 RUS76194.1 - 0.025 14.6 20.1 0.6 10.2 0.1 6.4 6 0 0 6 6 6 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 RUS76194.1 - 0.094 13.5 19.8 1 10.2 1.6 4.1 3 1 1 4 4 4 0 zinc-ribbon family zf-C2HC_2 PF13913.6 RUS76194.1 - 0.13 12.2 29.8 0.73 9.8 0.4 6.4 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Elf1 PF05129.13 RUS76194.1 - 0.15 12.2 19.2 0.14 12.2 0.7 4.4 1 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 RUS76194.1 - 0.89 9.6 18.2 1.2 9.2 3.0 4.1 2 1 1 3 3 3 0 Double zinc ribbon HypA PF01155.19 RUS76194.1 - 1 9.4 18.2 2 8.5 1.9 4.2 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 RUS76194.1 - 1.6 8.9 30.4 1.8 8.7 6.5 6.0 4 1 3 7 7 7 0 Zinc ribbon domain zf-MYST PF17772.1 RUS76194.1 - 7.5 6.2 10.3 6.7 6.4 0.8 4.1 2 2 2 4 4 4 0 MYST family zinc finger domain Laminin_EGF PF00053.24 RUS76195.1 - 0.0087 16.2 54.3 3.6 7.8 7.8 3.9 1 1 3 4 4 4 2 Laminin EGF domain Antistasin PF02822.14 RUS76195.1 - 1.2 9.8 0.2 1.2 9.8 0.2 7.4 4 3 4 8 8 8 0 Antistasin family TIL PF01826.17 RUS76195.1 - 2.3 8.6 47.2 14 6.1 16.5 4.0 1 1 2 3 3 3 0 Trypsin Inhibitor like cysteine rich domain TSP_1 PF00090.19 RUS76196.1 - 0.00071 19.8 13.7 0.00071 19.8 13.7 19.0 16 6 0 16 16 16 8 Thrombospondin type 1 domain NPR1_interact PF15699.5 RUS76196.1 - 0.15 12.7 0.9 0.55 10.9 0.4 2.0 2 0 0 2 2 2 0 NPR1 interacting PsbJ PF01788.17 RUS76197.1 - 1.9e-07 30.8 2.1 99 2.9 0.0 7.7 8 0 0 8 8 8 0 PsbJ Ntox8 PF15545.6 RUS76197.1 - 1.9e-06 27.9 4.9 52 4.0 0.0 7.2 1 1 7 8 8 8 0 Bacterial toxin 8 DUF3086 PF11285.8 RUS76197.1 - 4.6e-05 22.7 0.5 9.5 5.2 0.0 3.8 1 1 4 5 5 5 4 Protein of unknown function (DUF3086) Sirohm_synth_M PF14824.6 RUS76197.1 - 0.00027 20.3 0.1 2.5e+02 1.2 0.0 6.5 7 0 0 7 7 7 0 Sirohaem biosynthesis protein central Sld5 PF05916.11 RUS76197.1 - 0.02 15.4 18.8 1.8e+04 -9.0 18.8 7.0 1 1 0 1 1 1 0 GINS complex protein DUF4354 PF14263.6 RUS76198.1 - 0.52 10.1 4.9 0.43 10.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4354) CUB PF00431.20 RUS76202.1 - 5.4e-27 94.3 0.3 7.4e-21 74.6 0.2 2.1 2 0 0 2 2 2 2 CUB domain DUF2062 PF09835.9 RUS76202.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TMEM154 PF15102.6 RUS76202.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EMC3_TMCO1 PF01956.16 RUS76202.1 - 0.021 14.6 0.4 0.032 13.9 0.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Shisa PF13908.6 RUS76202.1 - 0.022 15.0 0.1 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Insulin_TMD PF17870.1 RUS76202.1 - 0.078 13.1 1.2 0.15 12.1 1.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Chordopox_A13L PF05961.11 RUS76202.1 - 1.2 9.5 4.1 2.7 8.3 4.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CUB PF00431.20 RUS76203.1 - 0.00026 21.3 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 RUS76204.1 - 2.8e-16 59.8 0.0 3.3e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 RUS76205.1 - 2.3e-06 28.6 0.2 9e-06 26.7 0.2 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Tetraspanin PF00335.20 RUS76206.1 - 7.8e-25 87.9 21.0 1.3e-24 87.2 21.0 1.4 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 RUS76206.1 - 0.014 15.0 16.5 0.05 13.2 4.0 2.4 2 0 0 2 2 2 0 SUR7/PalI family Tmemb_9 PF05434.11 RUS76206.1 - 1.2 9.0 6.5 0.52 10.2 1.4 2.3 2 0 0 2 2 2 0 TMEM9 DC_STAMP PF07782.13 RUS76206.1 - 3.9 7.2 5.9 2.2 8.1 0.5 2.4 2 1 0 2 2 2 0 DC-STAMP-like protein DUF4064 PF13273.6 RUS76206.1 - 5.1 7.4 17.4 7.2 6.9 10.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Fibrinogen_BP PF08017.11 RUS76208.1 - 0.0027 16.2 14.6 0.0035 15.9 14.6 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein MDM1 PF15501.6 RUS76208.1 - 0.014 14.6 26.3 0.017 14.3 26.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Ribosomal_S17 PF00366.20 RUS76208.1 - 0.1 12.7 6.4 15 5.8 0.3 3.6 1 1 4 5 5 5 0 Ribosomal protein S17 DUF2981 PF11200.8 RUS76208.1 - 3.9 7.1 14.0 6.2 6.5 14.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Thymidylate_kin PF02223.17 RUS76209.1 - 2.1e-41 141.6 0.0 2.7e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase Pec_lyase PF09492.10 RUS76209.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Pectic acid lyase MeaB PF03308.16 RUS76209.1 - 0.03 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RUS76209.1 - 0.041 14.4 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS76209.1 - 0.072 13.4 0.0 0.25 11.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain PPK2 PF03976.14 RUS76209.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RRM_1 PF00076.22 RUS76210.1 - 1.4e-19 69.7 0.0 2.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS76210.1 - 2.6e-07 30.7 0.0 6.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 RUS76210.1 - 0.0051 16.4 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS76210.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ATP-grasp_2 PF08442.10 RUS76211.1 - 2.3e-69 233.0 1.3 3.2e-69 232.5 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 RUS76211.1 - 5e-28 97.8 3.0 9.1e-28 97.0 3.0 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 RUS76211.1 - 4.6e-07 29.5 0.5 8.5e-07 28.6 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RUS76211.1 - 0.001 18.8 0.7 0.0042 16.9 0.3 2.1 1 1 1 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CDC48_2 PF02933.17 RUS76212.1 - 0.021 14.6 1.7 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 RIF5_SNase_2 PF18189.1 RUS76212.1 - 0.15 11.8 0.4 18 5.1 0.0 2.4 1 1 1 2 2 2 0 TbRIF5 SNase domain 2 GlcV_C_terminal PF17847.1 RUS76212.1 - 0.4 11.2 6.7 4.1 7.9 0.8 2.8 1 1 1 2 2 2 0 Glucose ABC transporter C-terminal domain EGF PF00008.27 RUS76213.1 - 8e-15 54.8 99.9 3.4e-07 30.4 9.7 7.9 8 0 0 8 8 8 5 EGF-like domain EGF_2 PF07974.13 RUS76213.1 - 6.4e-07 29.6 113.3 0.0016 18.7 7.3 7.8 7 0 0 7 7 7 4 EGF-like domain hEGF PF12661.7 RUS76213.1 - 6.2e-06 26.6 17.5 0.00018 22.0 5.6 8.7 9 0 0 9 9 9 5 Human growth factor-like EGF Cu-oxidase_3 PF07732.15 RUS76214.1 - 6.5e-38 129.4 0.4 7.3e-37 126.0 0.0 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RUS76214.1 - 1.6e-33 115.3 7.3 2e-31 108.5 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 RUS76214.1 - 4.8e-32 111.3 0.0 1.1e-29 103.6 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase DUF3752 PF12572.8 RUS76215.1 - 9.3e-13 49.0 13.3 9.3e-13 49.0 13.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) BEN PF10523.9 RUS76215.1 - 5.8e-07 29.7 0.1 1.2e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 BEN domain DDE_Tnp_IS1595 PF12762.7 RUS76215.1 - 0.0037 17.3 2.0 0.011 15.8 0.0 2.8 2 1 0 2 2 2 1 ISXO2-like transposase domain Not1 PF04054.15 RUS76215.1 - 2.9 6.7 6.1 5.4 5.8 6.1 1.3 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Na_H_Exchanger PF00999.21 RUS76217.1 - 1.6e-66 224.7 42.5 2.2e-66 224.2 42.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SdrD_B PF17210.3 RUS76219.1 - 9.9e-07 29.0 22.4 0.12 12.6 1.2 4.9 1 1 4 5 5 5 5 SdrD B-like domain CarboxypepD_reg PF13620.6 RUS76219.1 - 0.0028 17.9 2.4 56 4.1 0.0 4.2 1 1 3 4 4 4 0 Carboxypeptidase regulatory-like domain DUF4900 PF16241.5 RUS76219.1 - 0.0087 16.4 6.3 8.5 6.8 1.1 4.3 1 1 3 4 4 4 2 Domain of unknown function (DUF4900) RicinB_lectin_2 PF14200.6 RUS76219.1 - 0.025 15.3 2.0 5.7 7.7 1.7 3.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like SpaA PF17802.1 RUS76219.1 - 0.041 14.2 4.8 1e+02 3.3 4.8 3.9 1 1 0 1 1 1 0 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 RUS76219.1 - 1.2 9.2 14.1 29 4.8 0.3 4.7 1 1 3 4 4 4 0 CarboxypepD_reg-like domain R3H PF01424.22 RUS76219.1 - 1.6 8.8 8.2 18 5.4 2.8 4.2 1 1 2 3 3 3 0 R3H domain Big_3_3 PF13750.6 RUS76219.1 - 2.2 7.9 4.3 45 3.7 0.3 3.3 1 1 3 4 4 4 0 Bacterial Ig-like domain (group 3) DUF3657 PF12394.8 RUS76219.1 - 3.7 8.2 6.3 3.6e+02 1.8 3.5 3.8 1 1 1 2 2 2 0 Protein FAM135 PaREP1 PF05942.11 RUS76220.1 - 0.00072 19.5 0.2 1.8 8.5 0.0 3.9 1 1 3 5 5 5 1 Archaeal PaREP1/PaREP8 family NDUF_B7 PF05676.13 RUS76220.1 - 0.94 9.2 24.9 7.4 6.4 4.6 4.2 1 1 4 5 5 5 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CotJA PF11007.8 RUS76220.1 - 6.1 6.8 12.3 9.1 6.2 0.1 4.4 5 2 0 5 5 5 0 Spore coat associated protein JA (CotJA) A_thal_3526 PF09713.10 RUS76220.1 - 9 6.6 17.3 18 5.7 0.1 6.2 2 2 7 9 9 9 0 Plant protein 1589 of unknown function (A_thal_3526) PEX-2N PF09263.10 RUS76220.1 - 10 6.6 12.8 6.5 7.2 3.1 4.0 1 1 2 3 3 3 0 Peroxisome biogenesis factor 1, N-terminal CTP_transf_like PF01467.26 RUS76221.1 - 2.7e-26 92.5 0.0 4.8e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like IFR3_antag PF14754.6 RUS76223.1 - 0.095 11.9 1.0 0.11 11.7 1.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Med12 PF09497.10 RUS76224.1 - 0.0021 18.3 2.4 36 4.8 0.0 4.2 4 0 0 4 4 4 3 Transcription mediator complex subunit Med12 DUF4374 PF14298.6 RUS76224.1 - 1 8.1 8.8 18 4.0 0.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4374) DUF3474 PF11960.8 RUS76225.1 - 0.05 13.8 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Ribonuc_red_sm PF00268.21 RUS76226.1 - 1.1e-121 405.6 3.1 1.4e-121 405.3 3.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain IBR PF01485.21 RUS76228.1 - 6.4e-14 51.9 29.3 2.7e-10 40.3 8.0 4.9 2 2 3 5 5 5 2 IBR domain, a half RING-finger domain HtrL_YibB PF09612.10 RUS76229.1 - 5.8e-16 58.8 0.2 1.1e-15 57.9 0.2 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DUF4084 PF13321.6 RUS76229.1 - 0.087 12.4 2.7 2.6 7.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4084) Autophagy_act_C PF03987.15 RUS76230.1 - 1.9e-17 63.6 1.8 5.7e-17 62.1 1.8 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain LisH PF08513.11 RUS76231.1 - 0.097 12.7 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 LisH SSDP PF04503.13 RUS76231.1 - 0.36 11.1 1.3 0.43 10.8 1.3 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP SSDP PF04503.13 RUS76232.1 - 7.6e-22 78.9 26.7 1e-21 78.5 26.7 1.1 1 0 0 1 1 1 1 Single-stranded DNA binding protein, SSDP Mito_carr PF00153.27 RUS76234.1 - 1.4e-61 204.5 3.8 8e-23 80.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 RUS76234.1 - 0.021 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Fuseless Mago_nashi PF02792.14 RUS76235.1 - 1.7e-78 261.6 0.2 1.9e-78 261.4 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF5588 PF17826.1 RUS76236.1 - 1e-25 90.4 0.2 1.3e-25 90.1 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TPR_2 PF07719.17 RUS76236.1 - 1.3e-06 28.1 1.2 0.00011 22.0 0.9 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76236.1 - 3.1e-05 23.6 0.1 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 RUS76236.1 - 0.0016 18.7 0.5 0.68 10.3 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS76236.1 - 0.0028 18.3 0.3 0.0053 17.4 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS76236.1 - 0.0048 16.7 0.2 0.058 13.2 0.7 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS76236.1 - 0.013 16.3 0.0 0.97 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76236.1 - 0.092 13.0 0.1 23 5.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76236.1 - 0.11 12.9 0.0 4.8 7.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS76236.1 - 0.15 12.2 1.0 0.57 10.3 0.3 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF4081 PF13312.6 RUS76236.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) NDUF_B6 PF09782.9 RUS76237.1 - 5.5e-25 88.3 0.5 9e-25 87.6 0.5 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit SVWC PF15430.6 RUS76238.1 - 0.00016 21.9 7.2 0.00031 20.9 7.2 1.5 1 0 0 1 1 1 1 Single domain von Willebrand factor type C Phytochelatin PF05023.14 RUS76238.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Phytochelatin synthase tRNA-synt_2b PF00587.25 RUS76239.1 - 2e-28 99.6 0.1 2.3e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RUS76239.1 - 4.9e-09 36.2 0.1 1.2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain MIF4G PF02854.19 RUS76240.1 - 1.4e-15 57.5 1.2 3e-15 56.5 1.2 1.6 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 RUS76240.1 - 5.8e-06 25.6 0.0 0.007 16.0 0.0 2.6 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Homeodomain PF00046.29 RUS76242.1 - 0.0034 17.2 5.3 0.0072 16.2 5.3 1.5 1 0 0 1 1 1 1 Homeodomain cNMP_binding PF00027.29 RUS76244.1 - 2e-16 59.9 0.0 6.5e-14 51.8 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain zf-C2H2 PF00096.26 RUS76245.1 - 7e-16 57.7 69.1 2e-06 27.9 4.6 8.9 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76245.1 - 5.7e-14 51.6 66.0 0.00014 22.4 3.0 9.5 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS76245.1 - 2.9e-12 46.4 63.7 1.3e-07 31.7 3.8 9.4 10 0 0 10 10 10 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS76245.1 - 4.9e-07 29.4 49.5 0.00051 19.7 1.1 7.8 9 0 0 9 9 9 5 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 RUS76245.1 - 0.00036 20.3 0.9 0.00036 20.3 0.9 6.7 7 0 0 7 7 7 1 zinc-finger of a C2HC-type zf-met PF12874.7 RUS76245.1 - 0.00055 20.2 0.9 0.00055 20.2 0.9 7.7 7 1 0 7 7 7 2 Zinc-finger of C2H2 type Cys_rich_CWC PF14375.6 RUS76245.1 - 0.0031 17.9 3.5 0.0031 17.9 3.5 4.6 5 1 0 5 5 5 1 Cysteine-rich CWC zf-C2H2_6 PF13912.6 RUS76245.1 - 0.0077 16.2 1.3 0.0077 16.2 1.3 7.0 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS76245.1 - 0.051 13.9 1.2 0.051 13.9 1.2 7.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding Cobl PF09469.10 RUS76245.1 - 0.078 13.2 2.6 25 5.2 0.1 3.5 2 1 1 3 3 3 0 Cordon-bleu ubiquitin-like domain NDUFA12 PF05071.16 RUS76247.1 - 0.089 13.6 0.8 0.14 13.0 0.1 1.6 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 RVT_1 PF00078.27 RUS76248.1 - 3.1e-12 46.5 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRN3 PF05327.11 RUS76249.1 - 0.03 12.9 28.6 0.035 12.7 28.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 RUS76249.1 - 0.061 11.6 24.7 0.1 10.9 24.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS76249.1 - 0.077 11.2 35.3 0.0095 14.2 31.4 1.4 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 RUS76249.1 - 0.17 11.2 35.0 0.22 10.9 35.0 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS76249.1 - 0.57 8.6 27.4 0.77 8.1 27.4 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS76249.1 - 0.66 9.2 28.8 0.84 8.9 28.8 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RUS76249.1 - 1.1 7.3 53.9 1.6 6.7 53.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Fibrinogen_C PF00147.18 RUS76250.1 - 2.7e-55 187.6 4.1 3.9e-55 187.1 4.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HAUS-augmin3 PF14932.6 RUS76250.1 - 0.072 12.7 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4809 PF16067.5 RUS76252.1 - 0.012 15.7 15.5 0.4 10.9 1.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4809) Tcp10_C PF07202.13 RUS76252.1 - 0.026 14.5 8.4 1.4 8.8 9.1 2.1 1 1 0 1 1 1 0 T-complex protein 10 C-terminus Argos PF11581.8 RUS76252.1 - 0.53 10.3 21.6 9.4 6.3 1.1 4.2 1 1 2 3 3 3 0 Antagonist of EGFR signalling, Argos Peptidase_S3 PF00944.19 RUS76252.1 - 1.5 8.6 15.3 11 5.8 1.3 3.6 1 1 4 5 5 5 0 Alphavirus core protein Plasmodium_HRP PF05403.11 RUS76252.1 - 8.6 6.1 19.8 48 3.6 19.8 1.8 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) SOAR PF16533.5 RUS76253.1 - 0.13 12.2 3.6 10 6.1 1.8 2.3 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF3552 PF12072.8 RUS76253.1 - 0.26 10.7 6.3 0.43 10.0 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FCH PF00611.23 RUS76254.1 - 2.5e-15 56.5 0.8 1.2e-14 54.3 0.1 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain LemA PF04011.12 RUS76254.1 - 0.0031 17.4 3.8 0.007 16.2 2.0 2.4 1 1 1 2 2 2 1 LemA family DUF285 PF03382.14 RUS76254.1 - 0.032 14.0 2.0 0.51 10.1 0.1 2.7 2 1 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Seryl_tRNA_N PF02403.22 RUS76254.1 - 0.038 14.2 1.1 0.038 14.2 1.1 2.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SHE3 PF17078.5 RUS76254.1 - 8.7 6.0 18.7 0.022 14.5 5.1 2.5 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 SAM_1 PF00536.30 RUS76255.1 - 4.5e-13 49.4 0.0 6.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS76255.1 - 2.3e-08 34.0 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RUS76255.1 - 0.0095 15.9 0.2 0.021 14.8 0.2 1.6 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Filament PF00038.21 RUS76256.1 - 9.2e-06 25.4 62.7 9.2e-06 25.4 62.7 3.8 1 1 1 2 2 2 1 Intermediate filament protein GAS PF13851.6 RUS76256.1 - 0.0062 15.9 26.8 0.0062 15.9 26.8 4.8 3 1 2 5 5 5 2 Growth-arrest specific micro-tubule binding SAP PF02037.27 RUS76256.1 - 0.074 12.8 0.4 0.43 10.4 0.1 2.4 2 0 0 2 2 2 0 SAP domain TMEM144 PF07857.12 RUS76256.1 - 0.18 10.8 0.4 0.55 9.1 0.4 1.8 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters DUF1664 PF07889.12 RUS76256.1 - 1.5 8.9 48.3 0.32 11.0 5.5 5.8 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) DUF3800 PF12686.7 RUS76256.1 - 1.9 9.1 8.6 2.1e+03 -0.7 8.6 3.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF2722 PF10846.8 RUS76257.1 - 0.0066 15.4 5.1 0.0066 15.4 5.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) CT_C_D PF02682.16 RUS76257.1 - 0.027 14.2 0.9 0.046 13.5 0.9 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D ALS2CR11 PF15729.5 RUS76257.1 - 0.15 11.2 3.5 0.19 10.8 3.5 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 TFIIA PF03153.13 RUS76257.1 - 0.41 10.6 27.5 0.45 10.5 27.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF_4EBP PF05456.11 RUS76257.1 - 0.64 10.0 5.6 0.11 12.4 1.4 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FKBP_C PF00254.28 RUS76258.1 - 4.9e-28 97.3 0.4 1.3e-27 95.9 0.1 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 RUS76258.1 - 3e-10 40.0 0.6 5.5e-10 39.2 0.6 1.4 1 0 0 1 1 1 1 WH1 domain TPR_12 PF13424.6 RUS76259.1 - 1.9e-18 66.5 17.4 1.4e-09 38.1 0.1 4.8 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS76259.1 - 2.5e-12 46.8 7.6 7.4e-07 28.8 2.6 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 RUS76259.1 - 1.3e-10 40.8 9.9 0.18 11.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76259.1 - 5.3e-09 35.5 17.2 0.29 11.3 0.3 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76259.1 - 5.4e-09 35.6 19.2 0.027 14.6 0.1 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS76259.1 - 5.1e-08 32.4 22.0 0.00024 20.8 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS76259.1 - 3.9e-07 30.5 18.3 3.2e-06 27.6 0.2 5.1 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS76259.1 - 6.1e-06 26.6 9.8 12 7.0 0.6 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76259.1 - 5.3e-05 23.3 7.6 0.082 13.3 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS76259.1 - 0.00049 19.9 10.7 8.3 6.7 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPPII_N PF12583.8 RUS76259.1 - 0.14 12.7 1.9 12 6.5 0.3 2.7 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal TPR_4 PF07721.14 RUS76259.1 - 0.16 12.7 1.8 11 7.0 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 RUS76259.1 - 0.38 10.4 8.2 0.87 9.3 0.2 4.0 2 2 2 4 4 4 0 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 RUS76259.1 - 3.6 7.6 8.7 47 4.0 0.1 4.6 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 RUS76259.1 - 8.7 6.1 10.4 0.76 9.5 0.1 3.7 4 0 0 4 4 4 0 TPR repeat FAM222A PF15258.6 RUS76260.1 - 1.9 7.5 6.2 0.2 10.8 0.1 2.0 2 1 0 2 2 2 0 Protein family of FAM222A Allexi_40kDa PF05549.11 RUS76260.1 - 9.7 5.6 8.9 10 5.6 2.9 2.5 2 1 1 3 3 3 0 Allexivirus 40kDa protein DEAD PF00270.29 RUS76261.1 - 2.3e-32 112.1 0.0 3.8e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS76261.1 - 3.5e-24 85.3 0.0 1.6e-23 83.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS76261.1 - 0.0035 17.4 0.0 0.0098 15.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 RUS76262.1 - 3.1e-16 59.3 0.4 5.5e-16 58.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF4401 PF14351.6 RUS76264.1 - 0.019 14.3 2.5 0.032 13.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) RabGAP-TBC PF00566.18 RUS76265.1 - 1e-55 188.7 0.5 1e-55 188.7 0.5 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 RUS76265.1 - 6.5e-28 98.3 0.5 2.5e-27 96.4 0.0 2.4 2 1 0 2 2 2 1 Kinesin protein PID PF00640.23 RUS76265.1 - 2.7e-06 27.5 5.2 2.9e-06 27.4 0.1 3.0 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS76265.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain UPF0242 PF06785.11 RUS76265.1 - 0.0052 16.9 34.1 0.13 12.3 2.1 3.3 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RUS76265.1 - 0.25 11.4 8.7 3 7.9 1.5 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) MyTH4 PF00784.17 RUS76265.1 - 0.87 10.1 4.6 1.1 9.7 0.0 3.2 3 0 0 3 3 3 0 MyTH4 domain ATG16 PF08614.11 RUS76265.1 - 2.3 8.4 35.5 4 7.6 10.3 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fibrinogen_C PF00147.18 RUS76266.1 - 7.9e-15 55.3 0.2 1.2e-14 54.7 0.2 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EF-hand_7 PF13499.6 RUS76267.1 - 1.2e-07 32.1 0.0 0.023 15.1 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS76267.1 - 3.3e-07 29.4 1.9 2.2 8.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 RUS76267.1 - 4.1e-07 29.2 5.8 1.4 8.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RUS76267.1 - 1.5e-05 24.5 3.5 9.7 6.4 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS76267.1 - 0.027 14.8 0.1 0.097 13.0 0.0 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF533 PF04391.12 RUS76267.1 - 0.03 13.9 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) EF-hand_8 PF13833.6 RUS76267.1 - 0.048 13.5 5.7 9.6 6.1 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain pair TPR_14 PF13428.6 RUS76268.1 - 1.3e-19 69.2 6.7 0.44 11.5 0.0 11.8 8 3 5 13 13 11 4 Tetratricopeptide repeat Suf PF05843.14 RUS76268.1 - 2e-10 41.1 13.5 0.00013 22.0 1.8 6.3 5 2 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 RUS76268.1 - 6.1e-09 36.3 1.5 0.65 10.6 0.1 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76268.1 - 1e-08 34.6 13.5 0.04 14.0 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76268.1 - 2.8e-08 33.3 18.7 0.99 9.8 0.2 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RUS76268.1 - 9.2e-08 32.1 16.0 0.0011 18.9 0.6 6.6 5 1 1 6 6 6 1 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 RUS76268.1 - 2.7e-07 30.0 11.3 0.00065 18.9 0.1 5.4 3 2 3 6 6 6 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 RUS76268.1 - 1.7e-06 28.2 1.6 0.8 10.0 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS76268.1 - 2.2e-05 23.8 6.1 0.072 12.3 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76268.1 - 0.00077 19.9 5.0 32 5.5 0.0 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 RUS76268.1 - 0.0039 17.4 2.2 0.29 11.5 0.0 4.8 5 0 0 5 5 4 1 PPR repeat CEP209_CC5 PF16574.5 RUS76268.1 - 0.0085 16.3 0.2 0.04 14.1 0.2 2.1 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 MIT PF04212.18 RUS76268.1 - 0.011 15.8 0.1 0.59 10.2 0.1 3.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 RUS76268.1 - 0.012 16.3 5.1 24 5.7 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS76268.1 - 0.033 14.1 4.9 3.2 7.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 RUS76268.1 - 0.033 14.4 1.1 4.9 7.4 0.0 4.1 4 0 0 4 4 4 0 PPR repeat family TPR_7 PF13176.6 RUS76268.1 - 0.038 14.0 3.2 2.7 8.2 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS76268.1 - 0.057 13.3 6.6 12 5.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76268.1 - 0.094 13.1 12.6 10 6.8 0.0 7.5 8 1 0 8 8 7 0 Tetratricopeptide repeat HAT PF02184.16 RUS76268.1 - 0.13 12.3 13.5 4.1 7.5 0.1 7.2 8 0 0 8 8 7 0 HAT (Half-A-TPR) repeat GSK-3_bind PF05350.12 RUS76271.1 - 0.0038 16.6 1.0 0.072 12.4 0.6 2.0 1 1 1 2 2 2 2 Glycogen synthase kinase-3 binding LRR_8 PF13855.6 RUS76272.1 - 6.5e-44 147.5 39.1 7.3e-09 35.3 0.5 9.1 5 2 5 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 RUS76272.1 - 1.2e-27 95.5 43.2 4.5e-05 23.7 0.3 10.9 8 3 2 11 11 11 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS76272.1 - 5.3e-11 42.3 15.5 0.056 13.0 0.0 5.6 2 2 2 5 5 5 5 Leucine-rich repeat LRR_5 PF13306.6 RUS76272.1 - 9.4e-05 22.4 7.5 0.00099 19.1 0.7 4.4 3 2 1 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS76272.1 - 0.00045 20.0 23.7 7 7.0 0.2 9.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 RUS76272.1 - 0.33 11.6 47.8 0.59 10.9 0.2 12.7 15 2 1 16 16 16 0 Leucine Rich Repeat IL11 PF07400.11 RUS76272.1 - 1.2 8.8 6.4 2.8 7.6 3.6 2.6 1 1 0 2 2 2 0 Interleukin 11 SH3_9 PF14604.6 RUS76274.1 - 2.8e-09 36.7 0.2 4.6e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 RUS76274.1 - 4.9e-08 32.6 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 RUS76274.1 - 3.5e-05 23.3 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Peptidase_M13_N PF05649.13 RUS76277.1 - 1.3e-06 28.3 0.1 2.1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 DUF1206 PF06724.11 RUS76278.1 - 0.087 12.9 1.0 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DNA_pol_phi PF04931.13 RUS76279.1 - 0.00054 18.2 24.9 0.00068 17.9 24.9 1.0 1 0 0 1 1 1 1 DNA polymerase phi Sigma70_ner PF04546.13 RUS76279.1 - 0.00072 19.5 11.2 0.00092 19.1 11.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region CDC45 PF02724.14 RUS76279.1 - 0.00077 17.9 11.3 0.00094 17.6 11.3 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF4820 PF16091.5 RUS76279.1 - 0.002 17.5 5.3 0.0029 17.0 5.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) BSP_II PF05432.11 RUS76279.1 - 0.0035 17.1 24.2 0.0059 16.3 24.2 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 RUS76279.1 - 0.0081 16.3 18.6 0.015 15.5 18.6 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Astro_capsid_p PF12226.8 RUS76279.1 - 0.0084 15.3 9.8 0.0098 15.1 9.8 1.2 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Nop14 PF04147.12 RUS76279.1 - 0.017 13.4 22.5 0.021 13.0 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 RUS76279.1 - 0.031 14.5 7.3 0.046 13.9 7.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 RUS76279.1 - 0.055 13.3 13.8 0.07 13.0 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 RUS76279.1 - 0.095 12.4 20.5 0.13 12.0 20.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DDHD PF02862.17 RUS76279.1 - 0.1 12.8 0.8 0.12 12.5 0.8 1.1 1 0 0 1 1 1 0 DDHD domain PIP5K PF01504.18 RUS76279.1 - 0.12 11.6 0.3 0.16 11.1 0.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase YL1 PF05764.13 RUS76279.1 - 0.12 12.4 22.6 0.15 12.1 22.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Mpp10 PF04006.12 RUS76279.1 - 0.13 10.7 24.9 0.16 10.4 24.9 1.0 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 RUS76279.1 - 0.14 11.6 9.5 0.18 11.2 9.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RRN3 PF05327.11 RUS76279.1 - 0.16 10.5 10.8 0.19 10.2 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CLN3 PF02487.17 RUS76279.1 - 0.16 11.0 1.2 0.24 10.4 1.2 1.2 1 0 0 1 1 1 0 CLN3 protein AAA_23 PF13476.6 RUS76279.1 - 0.16 12.4 9.9 0.21 12.1 9.9 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 RUS76279.1 - 0.17 9.8 7.3 0.21 9.5 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 RUS76279.1 - 0.18 10.5 6.3 0.24 10.1 6.3 1.1 1 0 0 1 1 1 0 Presenilin RXT2_N PF08595.11 RUS76279.1 - 0.19 11.8 11.0 0.31 11.0 11.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RUS76279.1 - 0.2 10.8 27.7 0.25 10.4 27.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) O-antigen_lig PF13425.6 RUS76279.1 - 0.28 9.9 2.5 0.35 9.6 2.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FYDLN_acid PF09538.10 RUS76279.1 - 0.29 11.8 15.4 0.58 10.9 15.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 RUS76279.1 - 0.31 10.4 25.4 0.4 10.1 25.4 1.0 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 RUS76279.1 - 0.32 11.4 7.6 0.74 10.2 7.1 1.8 2 0 0 2 2 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 RUS76279.1 - 0.39 9.6 6.1 0.51 9.2 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RAB3GAP2_C PF14656.6 RUS76279.1 - 0.42 8.8 7.6 0.57 8.3 7.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Thg1C PF14413.6 RUS76279.1 - 0.44 10.7 4.2 0.7 10.1 4.2 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain BUD22 PF09073.10 RUS76279.1 - 0.53 9.6 20.2 0.69 9.2 20.2 1.0 1 0 0 1 1 1 0 BUD22 Serinc PF03348.15 RUS76279.1 - 0.56 9.1 1.9 0.73 8.7 1.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TLP-20 PF06088.11 RUS76279.1 - 0.62 9.9 4.6 1 9.3 4.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Prothymosin PF03247.14 RUS76279.1 - 0.63 10.5 42.8 0.88 10.1 42.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Spore_coat_CotO PF14153.6 RUS76279.1 - 0.64 9.9 14.9 0.92 9.4 14.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2722 PF10846.8 RUS76279.1 - 0.69 8.8 5.3 0.92 8.4 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GNAT_acetyltr_2 PF13718.6 RUS76279.1 - 0.91 8.9 6.1 1.3 8.3 6.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Tim54 PF11711.8 RUS76279.1 - 1.8 7.2 14.7 2.4 6.8 14.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 RUS76279.1 - 2.2 7.5 5.6 3 7.1 5.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 RUS76279.1 - 2.3 7.9 10.0 3.5 7.3 10.0 1.2 1 0 0 1 1 1 0 Connexin RPA43_OB PF17875.1 RUS76279.1 - 2.9 8.6 12.4 4.3 8.0 12.4 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Vfa1 PF08432.10 RUS76279.1 - 3.1 8.1 14.1 4.3 7.6 14.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 RUS76279.1 - 3.6 6.5 30.7 4.8 6.1 30.7 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 RUS76279.1 - 3.9 6.6 17.7 5.8 6.0 17.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 RUS76279.1 - 4.7 6.5 22.9 8 5.8 22.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PTPRCAP PF15713.5 RUS76279.1 - 5.4 7.3 28.1 7.8 6.8 28.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3306 PF11748.8 RUS76279.1 - 6.6 7.6 15.5 9.7 7.1 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Pox_Ag35 PF03286.14 RUS76279.1 - 7.1 6.4 19.9 10 5.8 19.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Saw1 PF11561.8 RUS76279.1 - 7.5 6.0 6.6 10 5.5 6.6 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 CDC27 PF09507.10 RUS76279.1 - 7.6 5.8 17.4 9.7 5.5 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Afi1 PF07792.12 RUS76279.1 - 7.6 7.0 11.7 12 6.4 11.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CobT PF06213.12 RUS76279.1 - 8.1 5.7 28.8 11 5.3 28.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 RUS76279.1 - 8.2 4.4 10.7 15 3.5 10.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RPN2_C PF18004.1 RUS76279.1 - 8.3 6.3 20.7 13 5.7 20.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DARPP-32 PF05395.12 RUS76279.1 - 8.3 6.6 21.5 12 6.0 21.5 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DDRGK PF09756.9 RUS76279.1 - 9.4 5.8 28.0 13 5.3 28.0 1.1 1 0 0 1 1 1 0 DDRGK domain XAP5 PF04921.14 RUS76279.1 - 9.7 5.9 14.3 13 5.5 14.3 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Gal-bind_lectin PF00337.22 RUS76280.1 - 3.3e-14 52.6 0.2 4.4e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin TPR_12 PF13424.6 RUS76281.1 - 4.3e-10 39.7 6.1 0.00013 22.2 0.0 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat AAA_16 PF13191.6 RUS76281.1 - 2.2e-08 34.7 0.1 1.2e-07 32.3 0.1 2.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RUS76281.1 - 2.7e-08 33.9 0.0 6.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_MalT PF17874.1 RUS76281.1 - 5.7e-05 22.6 2.7 0.012 15.0 0.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region Roc PF08477.13 RUS76281.1 - 0.00067 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TPR_10 PF13374.6 RUS76281.1 - 0.0009 19.0 3.3 3.9 7.5 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat DUF4062 PF13271.6 RUS76281.1 - 0.0029 18.0 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 1 1 Domain of unknown function (DUF4062) AAA PF00004.29 RUS76281.1 - 0.0034 17.8 0.0 0.015 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS76281.1 - 0.0037 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 RUS76281.1 - 0.029 14.0 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras family Rsbr_N PF08678.10 RUS76281.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Rsbr N terminal TPR_17 PF13431.6 RUS76281.1 - 0.1 13.0 0.1 26 5.5 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76281.1 - 1.6 9.0 11.1 0.89 9.8 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RUS76281.1 - 5.2 8.0 7.3 31 5.6 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat HSP90 PF00183.18 RUS76282.1 - 1.3e-222 740.3 32.8 1.3e-222 740.3 32.8 1.9 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 RUS76282.1 - 2.6e-13 50.5 0.1 2.6e-13 50.5 0.1 6.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RUS76282.1 - 2e-10 40.6 4.9 7.5e-10 38.8 0.2 5.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TSP_3 PF02412.18 RUS76282.1 - 0.0027 17.4 18.3 0.0033 17.1 3.4 71.1 16 14 57 75 75 75 54 Thrombospondin type 3 repeat RCC1 PF00415.18 RUS76283.1 - 1e-66 221.3 28.4 1.8e-15 57.3 0.5 8.8 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS76283.1 - 4.7e-34 115.5 35.0 1.1e-08 34.7 0.6 8.0 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat IKI3 PF04762.12 RUS76283.1 - 0.044 11.8 0.0 0.071 11.1 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Plk4_PB2 PF18409.1 RUS76284.1 - 0.00027 21.6 2.9 2.6 8.8 0.1 3.4 1 1 2 3 3 3 2 Polo-like Kinase 4 Polo Box 2 RTP1_C1 PF10363.9 RUS76284.1 - 0.0067 16.6 0.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF3556 PF12077.8 RUS76284.1 - 0.04 12.3 0.3 5.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein of unknown function (DUF3556) Sterile PF03015.19 RUS76284.1 - 0.056 13.7 1.5 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Male sterility protein MGDG_synth PF06925.11 RUS76284.1 - 0.061 13.4 0.1 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase MBF1 PF08523.10 RUS76284.1 - 0.17 12.4 0.4 0.17 12.4 0.4 2.4 3 0 0 3 3 3 0 Multiprotein bridging factor 1 BEN PF10523.9 RUS76284.1 - 0.21 11.9 2.4 19 5.6 0.2 2.6 2 0 0 2 2 2 0 BEN domain Seryl_tRNA_N PF02403.22 RUS76284.1 - 0.38 11.0 4.0 13 6.1 0.4 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TAF6_C PF07571.13 RUS76285.1 - 2.8e-27 94.9 0.1 7.8e-27 93.4 0.1 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 RUS76285.1 - 3.9e-24 84.6 0.1 9.8e-24 83.3 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 RUS76285.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.5 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 p450 PF00067.22 RUS76286.1 - 2e-69 234.5 0.0 2.3e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MtN3_slv PF03083.16 RUS76287.1 - 8.4e-20 70.6 15.0 3.7e-10 39.7 1.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Phage_holin_2_4 PF16082.5 RUS76287.1 - 0.048 13.4 0.4 0.15 11.8 0.4 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like KbaA PF14089.6 RUS76287.1 - 1.7 8.5 13.1 0.054 13.3 6.6 1.8 2 1 0 2 2 2 0 KinB-signalling pathway activation in sporulation SID-1_RNA_chan PF13965.6 RUS76287.1 - 9 4.6 12.1 11 4.3 12.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Transposase_1 PF01359.18 RUS76288.1 - 3.7e-19 68.3 0.0 8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS76288.1 - 8.8e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS76288.1 - 6.1e-05 23.2 0.2 0.00013 22.2 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS76288.1 - 0.00085 19.9 0.9 0.0028 18.2 0.0 2.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_48 PF17906.1 RUS76288.1 - 0.0015 18.6 0.3 0.0065 16.6 0.0 2.2 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS76288.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS76288.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 RUS76288.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 PCI domain DUF4817 PF16087.5 RUS76288.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS76288.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Arrestin_N PF00339.29 RUS76289.1 - 1.2e-24 87.1 0.0 3.3e-23 82.4 0.0 2.7 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS76289.1 - 8.1e-15 55.5 0.0 1.5e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS76289.1 - 0.055 12.6 0.1 0.26 10.4 0.0 2.0 1 1 1 2 2 2 0 Rgp1 UBA_3 PF09288.10 RUS76289.1 - 0.063 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain PUMA PF15826.5 RUS76289.1 - 0.1 12.8 0.2 0.98 9.6 0.3 2.1 1 1 1 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis WD40 PF00400.32 RUS76290.1 - 4.5e-15 55.8 21.0 4.4e-05 24.2 0.6 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RUS76290.1 - 3.7e-06 26.1 2.1 0.025 13.6 0.9 3.2 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RUS76290.1 - 7.6e-06 26.2 6.9 0.24 11.7 0.1 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Rab5ip PF07019.12 RUS76291.1 - 1.6e-17 63.8 7.9 2.1e-17 63.5 7.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF1961 PF09224.11 RUS76291.1 - 0.097 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Vma12 PF11712.8 RUS76291.1 - 0.24 11.5 2.5 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4618 PF15397.6 RUS76292.1 - 3.6e-64 216.7 19.8 4.6e-64 216.3 19.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CBF_beta PF02312.17 RUS76292.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.9 3 1 0 3 3 3 0 Core binding factor beta subunit DUF1759 PF03564.15 RUS76292.1 - 0.18 11.7 6.8 1 9.3 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DUF4407 PF14362.6 RUS76292.1 - 3.6 6.8 11.8 8.8 5.6 10.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 RUS76292.1 - 3.7 8.1 14.3 0.041 14.4 3.6 2.9 1 1 3 4 4 4 0 Spectrin repeat Wtap PF17098.5 RUS76292.1 - 4.7 7.1 26.7 2.3 8.2 1.4 4.4 4 2 0 4 4 4 0 WTAP/Mum2p family DUF4320 PF14208.6 RUS76292.1 - 6.2 6.9 5.6 1.4 9.0 1.2 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4320) Beta-lactamase PF00144.24 RUS76293.1 - 3.2e-43 148.2 0.1 5.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase BTRD1 PF17660.1 RUS76293.1 - 0.0026 17.5 0.1 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 Bacterial tandem repeat domain 1 DUF4638 PF15472.6 RUS76294.1 - 0.14 11.9 4.6 0.16 11.6 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4665 PF15679.5 RUS76294.1 - 2.1 9.0 23.3 17 6.1 23.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) WEMBL PF05701.11 RUS76295.1 - 0.022 13.5 0.6 0.028 13.1 0.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.12 RUS76295.1 - 0.049 14.1 1.1 0.5 10.9 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS76295.1 - 0.055 13.7 3.9 2.2 8.6 0.6 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 RUS76295.1 - 0.062 13.4 2.8 0.41 10.7 1.0 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 RUS76295.1 - 2.7 8.4 8.8 8.1 6.9 0.1 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PH PF00169.29 RUS76296.1 - 0.00011 22.7 0.1 0.00031 21.2 0.1 1.8 1 0 0 1 1 1 1 PH domain DUF4388 PF14332.6 RUS76296.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) FH2 PF02181.23 RUS76297.1 - 9.3e-64 215.9 3.5 1.1e-63 215.7 3.5 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain BAR_3 PF16746.5 RUS76297.1 - 0.00047 19.9 0.2 0.00089 19.0 0.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Chromo PF00385.24 RUS76298.1 - 1.6e-11 43.9 0.0 4.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 RUS76298.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Chromo shadow domain LMBR1 PF04791.16 RUS76298.1 - 0.49 9.3 2.9 0.68 8.8 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S64 PF08192.11 RUS76298.1 - 1.2 7.5 14.2 1.4 7.3 14.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF936 PF06075.12 RUS76298.1 - 1.9 7.3 26.0 2.4 7.0 26.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOBP PF15279.6 RUS76298.1 - 2.8 8.5 14.3 3.8 8.0 14.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3347 PF11827.8 RUS76298.1 - 4.4 7.4 10.4 6.7 6.9 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF5427 PF10310.9 RUS76298.1 - 6.8 5.5 18.1 9.6 5.0 18.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM76 PF16046.5 RUS76298.1 - 9.4 5.5 18.4 14 4.9 18.4 1.2 1 0 0 1 1 1 0 FAM76 protein SNF2_N PF00176.23 RUS76299.1 - 2.7e-61 207.2 0.1 2.7e-61 207.2 0.1 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS76299.1 - 7.8e-18 64.8 1.9 1e-17 64.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 RUS76299.1 - 9.1e-18 63.9 3.6 7.4e-10 38.6 0.5 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RUS76299.1 - 2.8e-06 27.4 3.2 4.7e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RUS76299.1 - 0.00023 20.4 0.2 0.0015 17.8 0.2 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 BRK PF07533.16 RUS76300.1 - 7e-32 108.8 0.1 4.8e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 BRK domain AT_hook PF02178.19 RUS76301.1 - 0.00012 21.5 6.3 0.16 11.9 0.6 2.8 2 0 0 2 2 2 2 AT hook motif FeoC PF09012.10 RUS76301.1 - 0.0021 18.1 0.1 15 5.8 0.0 3.2 3 0 0 3 3 3 1 FeoC like transcriptional regulator WPP PF13943.6 RUS76301.1 - 0.021 15.2 0.0 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 WPP domain DUF1651 PF07864.11 RUS76301.1 - 0.067 13.5 0.0 52 4.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1651) IMUP PF15761.5 RUS76301.1 - 0.15 12.7 20.1 0.51 11.1 3.3 3.1 1 1 2 3 3 3 0 Immortalisation up-regulated protein TMEM214 PF10151.9 RUS76301.1 - 3.1 6.1 5.4 8.4 4.7 1.1 1.9 1 1 1 2 2 2 0 TMEM214, C-terminal, caspase 4 activator SRPRB PF09439.10 RUS76303.1 - 3.9e-54 182.8 0.3 5.3e-54 182.4 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 RUS76303.1 - 5.4e-20 71.6 0.4 7.6e-20 71.1 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS76303.1 - 9e-08 32.2 0.1 1.4e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 RUS76303.1 - 1.2e-07 32.0 0.0 3.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 RUS76303.1 - 2.3e-07 30.5 0.8 4.6e-07 29.5 0.8 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RUS76303.1 - 3e-07 30.2 0.2 6e-07 29.2 0.2 1.5 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 RUS76303.1 - 1.1e-06 28.2 0.2 1.4e-06 27.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS76303.1 - 3.7e-06 26.6 0.2 5.3e-05 22.8 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RUS76303.1 - 0.0022 17.8 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA PF00004.29 RUS76303.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TMEM51 PF15345.6 RUS76303.1 - 0.091 12.6 1.6 0.28 11.0 1.6 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 RUS76303.1 - 3.1 7.6 4.7 5.6 6.8 4.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 6PGD PF00393.19 RUS76304.1 - 5.6e-93 311.5 0.0 8.9e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RUS76304.1 - 6.8e-51 172.6 0.1 1.1e-50 171.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RUS76304.1 - 0.0073 16.9 0.4 0.013 16.0 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PGK PF00162.19 RUS76304.1 - 0.059 12.3 0.1 0.089 11.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase IlvN PF07991.12 RUS76304.1 - 0.1 12.2 0.2 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 RUS76304.1 - 0.16 11.9 0.5 0.44 10.4 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 RUS76305.1 - 2.5e-64 217.2 0.0 3.4e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76305.1 - 5.9e-31 107.7 0.0 8.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RUS76305.1 - 6.9e-13 48.3 6.8 1.4e-12 47.3 6.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 RUS76305.1 - 8.4e-10 38.5 0.1 1.8e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 RUS76305.1 - 6.4e-08 33.2 1.1 1.3e-07 32.2 1.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RUS76305.1 - 8.5e-05 22.0 0.0 0.0003 20.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 RUS76305.1 - 0.0054 16.4 0.2 0.34 10.5 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS76305.1 - 0.015 15.3 0.3 0.052 13.5 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS76305.1 - 0.021 13.8 0.2 0.037 13.0 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain C1_2 PF03107.16 RUS76305.1 - 0.05 13.9 2.5 0.11 12.8 2.5 1.6 1 0 0 1 1 1 0 C1 domain Kdo PF06293.14 RUS76305.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 RUS76305.1 - 1.9 8.4 5.0 4.3 7.3 5.0 1.5 1 0 0 1 1 1 0 PHD-finger ArfGap PF01412.18 RUS76306.1 - 9.5e-41 138.5 0.1 2.1e-40 137.4 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RUS76306.1 - 5.2e-26 91.8 3.4 1.1e-25 90.8 3.4 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 RUS76306.1 - 4.7e-16 59.1 0.2 6.3e-09 36.3 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS76306.1 - 1.6e-12 47.3 0.3 0.00017 21.9 0.3 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RUS76306.1 - 3.8e-12 46.2 5.0 2.8e-06 27.5 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS76306.1 - 3.3e-11 42.4 1.2 0.036 14.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RUS76306.1 - 8.6e-10 39.0 0.9 0.00094 19.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.29 RUS76306.1 - 9.6e-06 26.1 0.1 2.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 PH domain LRR_8 PF13855.6 RUS76307.1 - 2.9e-50 167.9 36.4 5.1e-12 45.4 2.6 4.8 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS76307.1 - 3.7e-22 78.0 11.4 1.2e-06 28.7 0.5 6.4 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS76307.1 - 5.8e-09 35.3 10.0 1.7 9.5 0.0 7.6 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS76307.1 - 7.1e-09 35.4 9.7 0.00011 21.8 0.2 3.4 1 1 2 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 RUS76307.1 - 9.9e-09 35.2 0.0 3.9e-06 26.9 0.0 3.0 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS76307.1 - 1.3e-05 24.9 8.6 0.041 13.9 0.4 5.9 6 0 0 6 6 6 2 Leucine Rich repeat Sigma70_r4 PF04545.16 RUS76307.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.7 4 0 0 4 4 4 0 Sigma-70, region 4 LRRNT PF01462.18 RUS76307.1 - 1.5 8.6 5.5 1.7 8.4 3.2 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 RUS76308.1 - 1.2e-14 53.8 6.1 4.3e-12 45.6 1.8 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RUS76308.1 - 6.1e-07 29.7 2.7 0.006 17.0 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS76308.1 - 0.018 14.5 0.2 0.38 10.2 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat LRR_5 PF13306.6 RUS76308.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS76308.1 - 0.14 12.7 3.1 18 6.3 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Ssu72 PF04722.13 RUS76309.1 - 6e-88 293.4 1.4 6.8e-88 293.2 1.4 1.0 1 0 0 1 1 1 1 Ssu72-like protein EAL PF00563.20 RUS76309.1 - 0.024 14.2 0.2 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 EAL domain Hyphal_reg_CWP PF11765.8 RUS76309.1 - 0.028 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Nbl1_Borealin_N PF10444.9 RUS76309.1 - 0.6 9.8 3.8 0.68 9.6 0.2 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AA_permease PF00324.21 RUS76310.1 - 3.2e-78 263.4 38.6 4.5e-78 263.0 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 RUS76310.1 - 5.9e-20 71.7 2.2 5.5e-09 35.5 0.0 3.0 1 1 1 2 2 2 2 Solute carrier family 12 Wzz PF02706.15 RUS76310.1 - 0.16 12.3 1.0 4 7.8 0.0 2.7 2 0 0 2 2 2 0 Chain length determinant protein ShK PF01549.24 RUS76311.1 - 0.078 13.5 1.5 0.078 13.5 1.5 5.5 4 1 1 5 5 5 0 ShK domain-like PAT1 PF09770.9 RUS76314.1 - 7.9 4.6 7.9 11 4.2 7.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LBR_tudor PF09465.10 RUS76315.1 - 0.28 11.0 10.1 26 4.7 0.1 4.9 2 1 3 5 5 5 0 Lamin-B receptor of TUDOR domain CDK5_activator PF03261.15 RUS76315.1 - 2.3 7.7 11.9 1.2 8.7 2.0 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase 5 activator protein Ephrin_rec_like PF07699.13 RUS76316.1 - 2.9e-37 126.2 42.2 8.3e-12 44.7 5.8 4.3 4 0 0 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 RUS76316.1 - 3.1e-06 27.0 34.8 0.012 15.5 3.1 5.5 1 1 2 5 5 5 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS76316.1 - 0.00059 20.2 32.0 0.28 11.6 0.6 6.5 3 2 2 6 6 6 4 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 RUS76316.1 - 0.079 13.1 23.9 0.27 11.3 1.4 4.0 1 1 3 4 4 4 0 Predicted membrane protein (DUF2318) Furin-like_2 PF15913.5 RUS76316.1 - 0.21 11.8 21.7 0.09 12.9 3.6 3.1 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich zf-C2H2_3 PF13878.6 RUS76316.1 - 0.67 9.8 0.1 0.67 9.8 0.1 3.2 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO Ephrin_rec_like PF07699.13 RUS76317.1 - 7.9e-20 70.4 15.6 7.6e-11 41.6 2.4 2.3 2 1 0 2 2 2 2 Putative ephrin-receptor like Furin-like_2 PF15913.5 RUS76317.1 - 0.0061 16.7 2.8 0.0061 16.7 2.8 2.2 1 1 0 2 2 2 1 Furin-like repeat, cysteine-rich VSP PF03302.13 RUS76317.1 - 0.027 13.3 14.2 0.04 12.8 14.2 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein C1_1 PF00130.22 RUS76317.1 - 0.066 13.1 0.4 0.066 13.1 0.4 3.2 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TNFR_c6 PF00020.18 RUS76317.1 - 0.085 13.3 0.3 0.085 13.3 0.3 4.1 1 1 4 5 5 5 0 TNFR/NGFR cysteine-rich region MIP PF00230.20 RUS76318.1 - 9.2e-54 182.5 21.1 1.5e-53 181.8 21.1 1.3 1 1 0 1 1 1 1 Major intrinsic protein COX15-CtaA PF02628.15 RUS76320.1 - 4.1e-111 371.1 6.8 4.8e-111 370.9 6.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein YrhK PF14145.6 RUS76320.1 - 0.046 13.6 0.4 1.9 8.4 0.2 2.7 2 0 0 2 2 2 0 YrhK-like protein CutC PF03932.14 RUS76321.1 - 2.4e-37 128.4 0.0 3.7e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 CutC family SipA_VBS PF17985.1 RUS76321.1 - 0.16 11.9 0.9 0.7 9.9 0.1 2.3 2 0 0 2 2 2 0 SipA vinculin binding site zf-C3HC4_3 PF13920.6 RUS76322.1 - 4.7e-09 36.0 17.3 8.6e-09 35.1 17.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS76322.1 - 0.00087 19.1 16.4 0.0017 18.1 16.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Band_3_cyto PF07565.13 RUS76322.1 - 0.069 13.0 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain tRNA-synt_1c_C PF03950.18 RUS76322.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain zf-RING_5 PF14634.6 RUS76322.1 - 0.59 10.1 16.5 1.5 8.9 16.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain RIG-I_C-RD PF11648.8 RUS76323.1 - 4.2e-19 68.9 2.6 8.9e-19 67.8 2.6 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I DEAD PF00270.29 RUS76323.1 - 8.2e-15 55.0 0.1 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RUS76323.1 - 2.2e-11 44.0 0.3 1e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 RUS76323.1 - 7.2e-11 42.3 2.5 7.2e-11 42.3 2.5 2.5 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain Helicase_C PF00271.31 RUS76323.1 - 7.8e-10 39.1 0.5 8.3e-09 35.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Condensin2nSMC PF12422.8 RUS76323.1 - 0.026 14.7 0.4 0.37 11.0 0.0 2.7 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit TFIIE_beta PF02186.15 RUS76323.1 - 0.18 12.1 1.1 1 9.7 0.1 2.8 3 0 0 3 3 3 0 TFIIE beta subunit core domain DEAD PF00270.29 RUS76324.1 - 8.8e-20 71.2 0.0 8.8e-20 71.2 0.0 2.6 4 0 0 4 4 4 1 DEAD/DEAH box helicase ResIII PF04851.15 RUS76324.1 - 2.1e-19 70.2 6.9 6.7e-18 65.3 0.0 4.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 RUS76324.1 - 2.9e-19 69.5 6.8 2.9e-19 69.5 6.8 2.6 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 RUS76324.1 - 1.3e-18 67.3 0.1 4.3e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.31 RUS76324.1 - 2.1e-15 57.0 0.0 2.8e-14 53.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RUS76324.1 - 0.0004 20.7 0.2 0.0049 17.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS76324.1 - 0.0027 18.0 1.4 0.0049 17.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 RUS76324.1 - 0.0084 15.7 10.7 0.27 10.7 0.0 3.6 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain CARD_2 PF16739.5 RUS76324.1 - 0.019 15.0 0.7 0.39 10.7 0.2 2.9 2 0 0 2 2 2 0 Caspase recruitment domain Fanconi_A PF03511.14 RUS76324.1 - 0.037 14.0 0.1 0.15 12.0 0.1 2.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF4495 PF14906.6 RUS76325.1 - 7.6e-94 314.3 8.1 7.6e-94 314.3 8.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) Homeodomain PF00046.29 RUS76326.1 - 1.2e-21 76.3 1.8 4e-21 74.6 1.8 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS76326.1 - 0.0038 17.1 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain LMP PF04778.12 RUS76326.1 - 0.0041 17.0 1.2 0.0087 16.0 1.2 1.6 1 0 0 1 1 1 1 LMP repeated region 4HB_MCP_1 PF12729.7 RUS76326.1 - 0.0083 15.7 0.1 0.93 9.0 0.1 2.5 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction Nnf1 PF03980.14 RUS76326.1 - 0.54 10.6 5.6 0.19 12.1 0.3 2.5 2 1 0 2 2 2 0 Nnf1 WD40 PF00400.32 RUS76327.1 - 0.0082 17.0 6.3 0.04 14.8 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat TPR_1 PF00515.28 RUS76328.1 - 1.1e-26 91.5 18.8 9.6e-06 25.2 0.3 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC8 PF04049.13 RUS76328.1 - 1.5e-23 83.4 7.5 6.2e-21 74.9 7.5 2.9 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 RUS76328.1 - 9.7e-20 69.0 26.4 0.0038 17.2 0.1 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76328.1 - 9e-16 56.7 20.0 0.0024 17.9 0.0 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76328.1 - 6.1e-11 41.8 3.1 3.6e-06 26.6 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 RUS76328.1 - 7.1e-11 42.6 6.0 8.5e-05 23.1 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS76328.1 - 9.9e-11 41.5 17.8 0.00074 20.1 0.1 7.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS76328.1 - 6.7e-10 39.1 21.6 0.0053 17.0 3.0 7.4 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS76328.1 - 1.8e-09 38.0 7.5 0.17 12.4 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS76328.1 - 1.9e-08 34.4 25.7 9.9e-05 22.5 0.5 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RUS76328.1 - 3.9e-05 23.7 14.5 4 8.0 0.0 8.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS76328.1 - 8.2e-05 22.4 16.8 0.43 10.7 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76328.1 - 0.00026 21.4 24.7 0.32 11.7 0.4 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS76328.1 - 0.0073 16.4 2.2 0.24 11.6 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS76328.1 - 0.048 13.7 4.3 2.6 8.2 0.2 3.3 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 5 TypeIII_RM_meth PF12564.8 RUS76328.1 - 0.08 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 1 0 Type III restriction/modification enzyme methylation subunit TPR_10 PF13374.6 RUS76328.1 - 0.65 10.0 8.0 21 5.2 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Mucin PF01456.17 RUS76329.1 - 5.6e-05 23.2 20.3 0.0001 22.3 20.3 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Man-6-P_recep PF02157.15 RUS76329.1 - 0.0072 15.5 0.2 0.017 14.2 0.0 1.7 1 1 1 2 2 2 1 Mannose-6-phosphate receptor RIFIN PF02009.16 RUS76329.1 - 0.033 14.1 4.2 0.046 13.6 4.2 1.3 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 RUS76329.1 - 0.14 9.3 11.2 0.15 9.2 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 RUS76329.1 - 0.22 10.7 20.5 0.24 10.6 20.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Coilin_N PF15862.5 RUS76329.1 - 0.25 11.1 6.0 0.34 10.7 6.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4614 PF15391.6 RUS76329.1 - 0.38 10.7 22.9 0.56 10.2 22.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.13 RUS76329.1 - 0.84 8.4 8.7 1 8.0 8.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 RUS76329.1 - 1.8 7.3 4.6 2.3 6.9 4.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ASD2 PF08687.11 RUS76329.1 - 6.3 6.3 6.9 8.1 5.9 6.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Presenilin PF01080.17 RUS76329.1 - 6.3 5.4 11.4 8.6 5.0 11.4 1.1 1 0 0 1 1 1 0 Presenilin DAG_kinase_N PF14513.6 RUS76329.1 - 6.4 7.0 10.9 4.5 7.5 8.9 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus CUB PF00431.20 RUS76330.1 - 0.0018 18.6 0.0 0.0052 17.1 0.0 1.8 1 0 0 1 1 1 1 CUB domain Cadherin_C_2 PF16492.5 RUS76330.1 - 0.0054 17.5 1.9 0.013 16.2 0.0 2.6 2 1 0 2 2 2 1 Cadherin cytoplasmic C-terminal DUF4741 PF15897.5 RUS76330.1 - 0.078 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) DUF4711 PF15829.5 RUS76330.1 - 0.35 10.8 2.7 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Orf78 PF06024.12 RUS76330.1 - 2.8 8.3 3.8 2.1 8.7 0.0 2.6 2 1 0 2 2 2 0 Orf78 (ac78) Nop14 PF04147.12 RUS76331.1 - 2.8e-05 22.6 26.3 3.2e-05 22.4 26.3 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS76331.1 - 4.8e-05 23.0 25.1 5.5e-05 22.8 25.1 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 RUS76331.1 - 0.00043 20.5 25.6 0.00063 19.9 25.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein PRP1_N PF06424.12 RUS76331.1 - 0.0011 19.4 10.0 0.0013 19.2 10.0 1.2 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Mpp10 PF04006.12 RUS76331.1 - 0.0011 17.5 27.9 0.0014 17.2 27.9 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 RUS76331.1 - 0.0013 17.1 22.0 0.0016 16.9 22.0 1.1 1 0 0 1 1 1 1 CDC45-like protein CDC27 PF09507.10 RUS76331.1 - 0.0016 18.0 17.0 0.0018 17.8 17.0 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 BUD22 PF09073.10 RUS76331.1 - 0.0017 17.8 18.8 0.0018 17.7 18.8 1.1 1 0 0 1 1 1 1 BUD22 CCSAP PF15748.5 RUS76331.1 - 0.0036 17.5 14.0 0.0044 17.2 14.0 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated PTPRCAP PF15713.5 RUS76331.1 - 0.0056 17.0 26.5 0.01 16.1 26.5 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 RUS76331.1 - 0.0081 16.1 21.3 0.011 15.6 21.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region DDHD PF02862.17 RUS76331.1 - 0.0097 16.1 2.6 0.01 16.0 2.6 1.2 1 0 0 1 1 1 1 DDHD domain Neur_chan_memb PF02932.16 RUS76331.1 - 0.017 15.2 3.1 0.023 14.8 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cellulose_synt PF03552.14 RUS76331.1 - 0.018 13.6 1.8 0.022 13.3 1.8 1.0 1 0 0 1 1 1 0 Cellulose synthase RR_TM4-6 PF06459.12 RUS76331.1 - 0.022 14.6 22.7 0.03 14.2 22.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 RUS76331.1 - 0.042 13.7 11.4 0.054 13.3 11.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PPP4R2 PF09184.11 RUS76331.1 - 0.045 13.3 23.0 0.058 13.0 23.0 1.3 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 RUS76331.1 - 0.053 12.1 15.7 0.061 11.9 15.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SpoIIP PF07454.11 RUS76331.1 - 0.061 12.8 13.8 0.082 12.3 13.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TRAP_alpha PF03896.16 RUS76331.1 - 0.075 12.2 14.6 0.11 11.7 14.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 RUS76331.1 - 0.1 11.4 13.4 0.12 11.1 13.4 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 RUS76331.1 - 0.11 12.2 8.2 0.13 12.0 8.2 1.1 1 0 0 1 1 1 0 AAA domain Drc1-Sld2 PF11719.8 RUS76331.1 - 0.13 11.8 15.3 0.14 11.6 15.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Serinc PF03348.15 RUS76331.1 - 0.13 11.2 4.4 0.17 10.8 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 RUS76331.1 - 0.13 10.3 39.5 0.17 10.0 39.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 RUS76331.1 - 0.16 10.9 9.7 0.2 10.6 9.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 RUS76331.1 - 0.17 11.0 8.2 0.2 10.8 8.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 RUS76331.1 - 0.19 10.5 16.8 0.23 10.2 16.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 RUS76331.1 - 0.22 10.5 7.7 0.25 10.3 7.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 RUS76331.1 - 0.26 11.5 5.9 0.29 11.4 5.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Astro_capsid_p PF12226.8 RUS76331.1 - 0.29 10.3 17.3 0.37 9.9 17.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SUFU_C PF12470.8 RUS76331.1 - 0.34 10.9 8.2 0.58 10.2 8.2 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain LRIF1 PF15741.5 RUS76331.1 - 0.35 9.4 3.2 0.43 9.1 3.2 1.3 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Plasmodium_Vir PF05795.11 RUS76331.1 - 0.39 10.1 10.3 0.46 9.8 10.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LAP1C PF05609.12 RUS76331.1 - 0.43 9.6 13.6 0.5 9.4 13.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2151 PF10221.9 RUS76331.1 - 0.44 9.1 11.5 0.52 8.8 11.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4045 PF13254.6 RUS76331.1 - 0.47 10.0 14.5 0.58 9.7 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dynamin_N PF00350.23 RUS76331.1 - 0.49 10.4 2.9 0.6 10.1 2.9 1.3 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 RUS76331.1 - 0.52 10.8 17.2 0.66 10.4 17.2 1.1 1 0 0 1 1 1 0 AAA domain GET2 PF08690.10 RUS76331.1 - 0.61 9.7 7.2 0.8 9.3 7.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4820 PF16091.5 RUS76331.1 - 0.61 9.4 12.1 0.86 8.9 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ALMT PF11744.8 RUS76331.1 - 0.73 8.6 6.5 0.84 8.4 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 RUS76331.1 - 0.88 8.3 10.8 0.95 8.2 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 RUS76331.1 - 0.98 7.5 10.6 1.1 7.3 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAB3GAP2_C PF14656.6 RUS76331.1 - 1 7.5 8.0 1.2 7.3 8.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3391 PF11871.8 RUS76331.1 - 1.3 9.6 13.7 2.5 8.6 13.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) PA26 PF04636.13 RUS76331.1 - 1.4 7.7 8.4 1.6 7.5 8.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Lin-8 PF03353.15 RUS76331.1 - 1.5 8.3 17.5 1.9 8.0 17.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec62 PF03839.16 RUS76331.1 - 1.5 8.3 11.1 2.2 7.7 11.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CENP-N PF05238.13 RUS76331.1 - 1.5 8.0 8.8 1.9 7.7 8.8 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like XAP5 PF04921.14 RUS76331.1 - 1.6 8.5 16.8 2.6 7.8 16.8 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator TFIIF_alpha PF05793.12 RUS76331.1 - 1.7 7.2 42.4 2.6 6.6 42.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S64 PF08192.11 RUS76331.1 - 1.7 7.1 6.6 1.9 6.9 6.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF5523 PF17661.1 RUS76331.1 - 2 8.0 30.2 2.7 7.6 30.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Paf1 PF03985.13 RUS76331.1 - 2.2 7.2 38.1 3 6.7 38.1 1.1 1 0 0 1 1 1 0 Paf1 O-antigen_lig PF13425.6 RUS76331.1 - 2.7 6.7 7.4 3.4 6.4 7.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Mem_trans PF03547.18 RUS76331.1 - 3.1 6.1 3.9 3.9 5.8 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein GREB1 PF15782.5 RUS76331.1 - 3.1 4.8 7.1 3.4 4.7 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 RUS76331.1 - 3.3 7.8 7.4 5.7 7.0 7.4 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.12 RUS76331.1 - 3.8 6.8 35.2 5.2 6.4 35.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Apt1 PF10351.9 RUS76331.1 - 4.1 6.1 9.8 5.1 5.8 9.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMN PF06003.12 RUS76331.1 - 4.7 6.4 7.6 8.6 5.5 7.6 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) MDM10 PF12519.8 RUS76331.1 - 4.7 6.0 11.9 6.2 5.6 11.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SID-1_RNA_chan PF13965.6 RUS76331.1 - 5 5.4 5.0 5.7 5.2 5.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MCM_bind PF09739.9 RUS76331.1 - 5.7 5.3 12.1 7.1 5.0 12.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nop53 PF07767.11 RUS76331.1 - 5.9 6.2 34.4 8.6 5.6 34.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 RUS76331.1 - 6.1 6.8 57.6 8.4 6.4 57.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Vfa1 PF08432.10 RUS76331.1 - 7.2 6.9 22.0 11 6.3 22.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 EIIBC-GUT_N PF03612.14 RUS76331.1 - 8.2 6.1 11.2 14 5.3 11.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus STAC2_u1 PF16664.5 RUS76331.1 - 8.3 6.9 14.4 14 6.1 14.4 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RPN2_C PF18004.1 RUS76331.1 - 9.3 6.1 25.7 16 5.4 25.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Neurexophilin PF06312.12 RUS76332.1 - 0.0067 15.9 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Neurexophilin DUF680 PF05079.12 RUS76332.1 - 0.031 15.0 0.6 0.031 15.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF680) eIF3_p135 PF12807.7 RUS76332.1 - 0.37 10.8 1.5 0.74 9.8 1.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Ribosomal_L38e PF01781.18 RUS76333.1 - 2.1e-36 123.8 3.1 2.6e-36 123.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF3492 PF11997.8 RUS76333.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DBC1 PF14443.6 RUS76334.1 - 5.1e-49 165.4 2.5 1.3e-47 160.8 0.0 3.2 3 0 0 3 3 3 1 DBC1 S1-like PF14444.6 RUS76334.1 - 8.6e-32 108.9 0.2 1.8e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 S1-like SAP PF02037.27 RUS76334.1 - 6e-06 25.9 0.2 1.5e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 SAP domain DUF2457 PF10446.9 RUS76334.1 - 0.00047 19.4 8.1 0.00047 19.4 8.1 4.9 5 1 0 5 5 5 1 Protein of unknown function (DUF2457) DUF2722 PF10846.8 RUS76334.1 - 0.00052 19.1 4.0 0.00052 19.1 4.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF2722) Med15 PF09606.10 RUS76334.1 - 0.12 11.0 44.5 0.28 9.8 44.5 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Bax1-I PF01027.20 RUS76335.1 - 4.2e-41 141.1 13.2 6.4e-41 140.5 13.2 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Thioredoxin_4 PF13462.6 RUS76336.1 - 0.0025 18.0 2.5 0.0034 17.6 2.5 1.3 1 1 0 1 1 1 1 Thioredoxin HSP70 PF00012.20 RUS76336.1 - 5 5.2 10.0 5.5 5.0 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Folliculin PF11704.8 RUS76336.1 - 7.8 6.3 7.1 11 5.9 7.1 1.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PALB2_WD40 PF16756.5 RUS76337.1 - 0.037 13.0 1.9 0.039 12.9 0.2 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain zf-3CxxC_2 PF17180.4 RUS76338.1 - 6.2e-10 39.7 22.1 1.3e-07 32.2 22.1 2.7 1 1 0 1 1 1 1 Zinc-binding domain zf-3CxxC PF13695.6 RUS76338.1 - 1.1e-07 32.2 15.4 1.9e-07 31.4 15.4 1.5 1 1 0 1 1 1 1 Zinc-binding domain Snurportin1 PF11538.8 RUS76338.1 - 0.021 15.0 1.5 0.036 14.3 1.5 1.3 1 0 0 1 1 1 0 Snurportin1 PhnA_Zn_Ribbon PF08274.12 RUS76338.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.3 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf_UBZ PF18439.1 RUS76338.1 - 9.5 5.9 14.5 5.1 6.8 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HH_signal PF01085.18 RUS76339.1 - 2.9e-06 27.0 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain G-alpha PF00503.20 RUS76341.1 - 4.7e-97 325.3 6.2 5.5e-97 325.1 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS76341.1 - 8.6e-14 51.4 1.0 6.3e-10 38.8 0.1 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS76341.1 - 0.0077 15.8 0.0 0.42 10.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS76341.1 - 0.026 14.6 0.0 7 6.8 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS76341.1 - 0.068 12.9 0.1 0.2 11.4 0.1 1.8 1 1 1 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RUS76341.1 - 0.085 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-LITAF-like PF10601.9 RUS76342.1 - 6.8e-22 77.5 20.5 8.7e-22 77.2 20.5 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 RUS76342.1 - 0.093 12.3 3.8 0.46 10.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger G0-G1_switch_2 PF15103.6 RUS76343.1 - 0.032 14.7 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 V_ATPase_I PF01496.19 RUS76343.1 - 0.16 9.9 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Saf_2TM PF18303.1 RUS76343.1 - 0.99 9.0 6.7 6.8 6.3 0.1 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain EphA2_TM PF14575.6 RUS76344.1 - 0.43 11.5 0.1 0.43 11.5 0.1 2.8 1 1 2 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PMP22_Claudin PF00822.20 RUS76345.1 - 0.0016 18.3 1.0 0.063 13.2 1.0 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family GRP PF07172.11 RUS76345.1 - 0.012 16.3 2.2 0.012 16.3 2.2 2.3 1 1 1 2 2 2 0 Glycine rich protein family RNase_H PF00075.24 RUS76346.1 - 1.6e-07 31.6 0.0 7.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS76346.1 - 0.051 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like CAP_N PF01213.19 RUS76346.1 - 0.11 11.9 5.5 0.17 11.3 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 RUS76346.1 - 0.25 11.4 2.9 0.45 10.5 2.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.16 RUS76347.1 - 1.5e-11 43.8 34.2 4.1e-06 26.0 10.8 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS76347.1 - 3.6e-08 32.7 2.7 3.6e-08 32.7 2.7 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS76348.1 - 2.3e-09 36.7 35.6 5.3e-05 22.3 11.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS76348.1 - 2.1e-07 30.2 3.5 2.1e-07 30.2 3.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter zf-AN1 PF01428.16 RUS76349.1 - 1.2e-22 79.7 29.7 8.3e-12 45.1 12.6 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 RUS76349.1 - 0.02 15.2 5.0 0.02 15.2 5.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C2H2 PF00096.26 RUS76349.1 - 0.5 10.9 8.6 2.2 8.9 1.8 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Copine PF07002.16 RUS76350.1 - 4.9e-87 290.9 0.0 6.8e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS76350.1 - 1.5e-27 95.8 0.0 1.5e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 RUS76350.1 - 0.00011 22.4 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 RUS76350.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain CLPTM1 PF05602.12 RUS76351.1 - 3e-128 428.5 1.1 3.5e-128 428.3 1.1 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 RUS76351.1 - 0.072 12.9 3.3 0.53 10.1 0.0 3.5 3 0 0 3 3 3 0 PQ loop repeat Tail_spike_N PF18668.1 RUS76352.1 - 0.017 15.0 0.1 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain STOP PF05217.12 RUS76354.1 - 0.00057 20.1 2.3 0.00057 20.1 2.3 4.6 6 0 0 6 6 6 1 STOP protein Hormone_2 PF00123.20 RUS76354.1 - 8.7 6.3 5.3 48 4.0 0.2 3.3 3 0 0 3 3 3 0 Peptide hormone Integrin_beta PF00362.18 RUS76355.1 - 3.6e-83 279.0 0.0 5.1e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 RUS76355.1 - 3.5e-17 61.8 0.3 7.3e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 RUS76355.1 - 5.9e-11 42.3 25.7 9e-09 35.3 7.1 6.4 8 0 0 8 8 8 4 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 RUS76355.1 - 1.5e-10 40.7 11.7 1.5e-10 40.7 11.7 3.6 3 0 0 3 3 3 1 Integrin plexin domain EGF_2 PF07974.13 RUS76355.1 - 2.7e-09 37.2 98.1 4.3e-05 23.8 12.0 6.5 5 2 1 6 6 6 4 EGF-like domain DUF5305 PF17231.2 RUS76355.1 - 0.015 14.7 0.1 0.063 12.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Ribosomal_S19 PF00203.21 RUS76356.1 - 1.6e-37 127.2 0.7 2.3e-37 126.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 U-box PF04564.15 RUS76357.1 - 2.2e-18 66.2 0.4 8.2e-18 64.3 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-RING_5 PF14634.6 RUS76357.1 - 0.00084 19.3 10.7 0.0028 17.6 10.7 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS76357.1 - 0.0013 19.0 9.3 0.0013 19.0 9.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS76357.1 - 0.007 16.4 7.0 0.007 16.4 7.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS76357.1 - 0.052 13.4 10.4 0.15 12.0 10.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L37e PF01907.19 RUS76357.1 - 0.059 13.5 5.9 0.21 11.8 5.9 1.9 1 0 0 1 1 1 0 Ribosomal protein L37e zf-C3HC4_2 PF13923.6 RUS76357.1 - 0.22 11.4 11.0 0.57 10.1 11.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS76357.1 - 0.5 10.3 17.1 0.025 14.4 10.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 RUS76357.1 - 1.3 9.2 9.5 1 9.5 7.3 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C4_ClpX PF06689.13 RUS76357.1 - 2.8 7.9 9.3 0.11 12.4 1.3 2.5 2 0 0 2 2 2 0 ClpX C4-type zinc finger DUF4205 PF13898.6 RUS76358.1 - 3.2e-127 424.2 0.0 4.5e-127 423.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) SNAP PF14938.6 RUS76359.1 - 2.2e-11 43.7 4.6 4e-11 42.9 4.6 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RUS76359.1 - 3.4e-07 30.4 0.3 0.00024 21.4 0.1 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76359.1 - 1.5e-05 24.7 0.9 0.025 14.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS76359.1 - 0.00019 21.1 0.0 0.023 14.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76359.1 - 0.0024 17.5 0.0 1.7 8.4 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 RUS76359.1 - 0.033 14.4 0.1 7 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS76359.1 - 0.078 13.6 1.6 1.1 10.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS76359.1 - 0.12 12.9 0.4 0.12 12.9 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FA_hydroxylase PF04116.13 RUS76360.1 - 2.3e-22 79.8 14.7 2.3e-22 79.8 14.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MAPEG PF01124.18 RUS76363.1 - 7.8e-08 32.3 0.9 1e-07 31.9 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Fibrinogen_C PF00147.18 RUS76364.1 - 1e-48 166.1 4.5 1.2e-48 165.8 4.5 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Sulfatase PF00884.23 RUS76366.1 - 3.6e-56 190.8 0.1 4.1e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS76366.1 - 3.7e-08 33.4 0.1 3.9e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3024 PF11225.8 RUS76367.1 - 2.1e-06 27.9 18.1 1.7 8.9 0.4 7.4 1 1 6 8 8 8 2 Protein of unknown function (DUF3024) MgtE_N PF03448.17 RUS76367.1 - 5.7e-05 23.7 13.6 1.1 9.9 0.4 5.1 1 1 3 5 5 5 3 MgtE intracellular N domain CagA PF03507.13 RUS76367.1 - 0.00032 20.7 6.5 0.17 11.8 0.7 3.0 1 1 2 3 3 3 2 CagA exotoxin Spin-Ssty PF02513.17 RUS76367.1 - 0.00052 19.7 12.9 27 4.6 0.3 8.0 3 3 8 11 11 11 0 Spin/Ssty Family PDZ_1 PF12812.7 RUS76367.1 - 0.00071 19.5 19.1 12 6.0 0.1 6.6 1 1 7 8 8 8 1 PDZ-like domain SpvB PF03534.13 RUS76367.1 - 0.0011 18.2 20.4 1.9 7.6 1.7 5.2 1 1 5 6 6 6 6 Salmonella virulence plasmid 65kDa B protein AAA_10 PF12846.7 RUS76367.1 - 0.0042 16.1 7.9 0.25 10.2 1.2 3.2 1 1 3 4 4 4 2 AAA-like domain DUF3861 PF12977.7 RUS76367.1 - 0.041 14.0 21.6 21 5.3 1.6 6.5 1 1 6 7 7 7 0 Domain of Unknown Function with PDB structure (DUF3861) DNA_ligase_OB_2 PF14743.6 RUS76367.1 - 0.078 13.0 11.0 28 4.8 0.1 5.8 1 1 5 6 6 6 0 DNA ligase OB-like domain GLTP PF08718.11 RUS76367.1 - 0.11 12.7 12.7 5.4 7.3 3.3 3.9 1 1 2 3 3 3 0 Glycolipid transfer protein (GLTP) Tn7_Tnp_TnsA_C PF08721.11 RUS76367.1 - 0.12 13.1 9.0 25 5.6 0.1 4.5 1 1 4 5 5 5 0 TnsA endonuclease C terminal VAPB_antitox PF02697.14 RUS76367.1 - 1.5 9.7 29.5 12 6.8 0.7 5.4 1 1 6 7 7 7 0 Putative antitoxin RTP1_C2 PF10304.9 RUS76367.1 - 1.9 8.2 40.3 5.1 6.9 0.5 9.3 9 2 3 12 12 12 0 Required for nuclear transport of RNA pol II C-terminus 2 Clathrin PF00637.20 RUS76367.1 - 3 7.7 14.1 33 4.3 2.8 5.0 1 1 2 3 3 3 0 Region in Clathrin and VPS NapD PF03927.13 RUS76367.1 - 4.2 7.5 28.0 23 5.2 1.3 5.6 1 1 6 7 7 7 0 NapD protein DUF4976 PF16347.5 RUS76368.1 - 0.0019 18.4 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 RUS76368.1 - 0.0028 18.4 0.0 0.029 15.1 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF1793 PF08760.11 RUS76368.1 - 0.09 13.2 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) DUF4994 PF16385.5 RUS76368.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function UPF0565 PF10561.9 RUS76369.1 - 0.02 14.1 6.4 0.029 13.6 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Borrelia_P83 PF05262.11 RUS76369.1 - 0.14 10.6 23.4 0.24 9.9 23.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3_zeta PF05091.12 RUS76369.1 - 0.14 11.1 27.4 0.22 10.5 27.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4638 PF15472.6 RUS76369.1 - 0.2 11.4 16.6 0.34 10.6 16.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Exonuc_VII_L PF02601.15 RUS76369.1 - 0.31 10.6 23.5 0.92 9.0 24.1 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit PAT1 PF09770.9 RUS76369.1 - 0.38 9.0 41.2 0.54 8.5 41.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPL5 PF18168.1 RUS76369.1 - 0.44 9.8 15.2 0.81 8.9 15.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Tim54 PF11711.8 RUS76369.1 - 0.48 9.2 19.6 1.3 7.8 19.6 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 RUS76369.1 - 0.64 9.2 7.2 0.96 8.6 7.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 RUS76369.1 - 0.65 8.8 9.2 0.88 8.3 9.2 1.2 1 0 0 1 1 1 0 Otopetrin V_ATPase_I PF01496.19 RUS76369.1 - 0.67 7.8 21.6 0.88 7.4 21.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIG-S PF10510.9 RUS76369.1 - 1.4 7.7 20.0 2 7.1 20.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF3807 PF12720.7 RUS76369.1 - 1.5 9.1 38.7 0.022 15.0 29.8 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3807) Connexin PF00029.19 RUS76369.1 - 1.5 8.5 15.8 2.6 7.7 15.8 1.4 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 RUS76369.1 - 1.6 7.7 24.6 2.5 7.0 24.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 RUS76369.1 - 2.1 7.1 17.5 3.2 6.5 17.5 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4770 PF15994.5 RUS76369.1 - 2.3 8.4 21.7 5.9 7.1 21.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) RXT2_N PF08595.11 RUS76369.1 - 2.9 7.9 21.3 0.18 11.8 15.3 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal GvpL_GvpF PF06386.11 RUS76369.1 - 2.9 7.7 22.8 5.5 6.8 22.8 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Phage_GPO PF05929.11 RUS76369.1 - 3.3 7.3 24.0 5.3 6.6 24.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PA26 PF04636.13 RUS76369.1 - 3.4 6.5 19.6 5.2 5.9 19.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Baculo_PP31 PF05311.11 RUS76369.1 - 3.7 6.9 20.1 6.6 6.1 20.1 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Dicty_REP PF05086.12 RUS76369.1 - 4.8 5.0 11.5 5.8 4.8 11.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM60A PF15396.6 RUS76369.1 - 6.2 6.8 23.4 0.88 9.5 18.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF3408 PF11888.8 RUS76369.1 - 6.3 6.9 25.4 23 5.1 25.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Membralin PF09746.9 RUS76369.1 - 7.4 5.5 16.0 13 4.7 16.0 1.4 1 0 0 1 1 1 0 Tumour-associated protein CSG2 PF16965.5 RUS76369.1 - 7.5 5.4 13.5 11 4.8 13.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Band_3_cyto PF07565.13 RUS76369.1 - 8 6.2 25.2 17 5.1 25.2 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HAT_KAT11 PF08214.11 RUS76369.1 - 8.2 5.6 19.1 12 5.0 19.1 1.2 1 0 0 1 1 1 0 Histone acetylation protein Rtf2 PF04641.12 RUS76369.1 - 8.6 5.6 23.7 19 4.5 23.7 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger MMU163 PF17119.5 RUS76369.1 - 9.4 5.3 14.5 23 4.0 14.5 1.6 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 RUS76370.1 - 0.0026 16.8 0.0 0.0054 15.7 0.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OAD_gamma PF04277.13 RUS76370.1 - 0.024 15.2 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.6 RUS76371.1 - 0.0071 16.6 0.1 0.0071 16.6 0.1 3.1 1 1 2 3 3 3 1 Wnt and FGF inhibitory regulator CCAP PF11105.8 RUS76371.1 - 0.16 11.9 0.6 0.26 11.3 0.6 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Hum_adeno_E3A PF05393.11 RUS76371.1 - 0.22 11.5 1.2 4.7 7.2 0.1 2.6 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein DUF2781 PF10914.8 RUS76372.1 - 4.6e-13 49.8 10.7 4.6e-13 49.8 10.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) DUF2798 PF11391.8 RUS76372.1 - 2 8.5 0.0 2 8.5 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2798) TRC8_N PF13705.6 RUS76373.1 - 2.2e-70 238.0 43.4 2.6e-70 237.8 43.4 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 RUS76373.1 - 1.8e-11 44.2 8.3 5e-11 42.8 8.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS76373.1 - 2.8e-10 39.9 7.9 6.2e-10 38.8 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS76373.1 - 8.8e-10 38.7 6.1 2.1e-09 37.5 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS76373.1 - 1.5e-08 34.5 4.1 3.4e-08 33.4 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS76373.1 - 1.2e-07 31.5 5.1 2.7e-07 30.3 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS76373.1 - 1.4e-07 31.3 7.7 3.6e-07 30.0 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS76373.1 - 1.3e-05 24.9 5.3 4e-05 23.4 5.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RUS76373.1 - 0.00024 21.1 5.5 0.00072 19.6 5.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RUS76373.1 - 0.00024 21.0 7.2 0.00024 21.0 7.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 RUS76373.1 - 0.00026 20.6 4.0 0.00078 19.1 4.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 RUS76373.1 - 0.00087 18.9 5.5 0.0024 17.4 5.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 RUS76373.1 - 0.0067 16.3 0.2 2.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.8 RUS76373.1 - 0.018 14.8 3.8 0.04 13.7 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 RUS76373.1 - 0.026 14.6 4.3 0.084 13.0 4.3 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 RUS76373.1 - 0.12 12.5 7.5 0.4 10.9 7.5 1.9 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 RUS76373.1 - 0.16 12.2 5.9 0.65 10.2 5.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 RUS76373.1 - 0.27 11.2 7.8 0.45 10.5 3.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 RUS76373.1 - 0.28 10.9 11.6 0.35 10.6 6.3 3.0 2 1 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 RUS76373.1 - 0.46 10.7 11.7 0.074 13.2 7.3 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 RUS76373.1 - 1.4 9.3 6.8 3.5 8.0 6.8 1.8 1 0 0 1 1 1 0 RING-like domain zf-RING_10 PF16685.5 RUS76373.1 - 3.2 8.0 6.9 7 6.9 4.0 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-H2C2_2 PF13465.6 RUS76374.1 - 1.7e-34 116.7 50.3 1.5e-06 28.4 0.1 8.8 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76374.1 - 2.4e-28 96.9 53.4 0.00044 20.5 1.1 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76374.1 - 2.4e-21 74.6 52.9 0.0079 17.0 1.0 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 RUS76374.1 - 3.7e-12 46.2 38.3 0.049 14.0 0.3 8.3 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS76374.1 - 1e-07 32.0 27.4 0.019 15.2 0.2 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS76374.1 - 5.7e-05 23.3 15.2 0.00077 19.7 4.4 5.2 2 1 5 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS76374.1 - 0.0018 18.9 16.4 7.2 7.3 0.2 6.2 2 1 4 6 6 6 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 RUS76374.1 - 0.0019 18.1 44.5 0.092 12.8 0.9 8.8 8 0 0 8 8 8 3 C2H2-type zinc finger BolA PF01722.18 RUS76374.1 - 0.0044 17.3 4.1 0.12 12.7 0.5 3.9 1 1 2 3 3 3 1 BolA-like protein Endonuclease_7 PF02945.15 RUS76374.1 - 0.0066 16.3 20.2 0.017 15.0 3.4 4.3 2 1 2 4 4 4 2 Recombination endonuclease VII ARS2 PF04959.13 RUS76374.1 - 0.01 16.3 8.0 0.31 11.4 0.8 3.6 1 1 1 3 3 3 1 Arsenite-resistance protein 2 AT_hook PF02178.19 RUS76374.1 - 0.026 14.4 1.1 0.068 13.1 1.1 1.7 1 0 0 1 1 1 0 AT hook motif zf-Sec23_Sec24 PF04810.15 RUS76374.1 - 0.031 14.3 14.0 26 5.0 0.6 6.4 6 1 1 7 7 7 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 RUS76374.1 - 0.044 13.9 20.6 3.1 8.0 0.8 5.5 4 1 1 5 5 5 0 Zinc ribbon domain zf_UBZ PF18439.1 RUS76374.1 - 0.1 12.2 27.6 0.9 9.2 0.5 7.2 8 0 0 8 8 7 0 Ubiquitin-Binding Zinc Finger CCAP PF11105.8 RUS76374.1 - 0.52 10.3 3.3 0.76 9.7 0.2 2.6 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-C2HE PF16278.5 RUS76374.1 - 0.67 10.4 25.6 1.3 9.5 0.1 6.7 3 1 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger C1_1 PF00130.22 RUS76374.1 - 0.96 9.4 24.2 6.4 6.8 0.4 5.8 3 1 2 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.7 RUS76374.1 - 1.4 9.3 35.1 9.6 6.6 0.7 6.9 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 RUS76374.1 - 2.3 9.0 23.8 11 6.9 3.7 4.5 1 1 3 4 4 4 0 zinc-ribbon family DZR PF12773.7 RUS76374.1 - 2.7 8.1 19.5 6.5 6.9 5.9 4.4 2 2 1 3 3 3 0 Double zinc ribbon LIM PF00412.22 RUS76374.1 - 7.2 6.9 23.3 2.8 8.3 3.0 5.3 2 1 4 6 6 6 0 LIM domain Sulfotransfer_3 PF13469.6 RUS76375.1 - 1.1e-07 32.5 1.2 0.00042 20.8 1.2 3.5 1 1 0 1 1 1 1 Sulfotransferase family PGA2 PF07543.12 RUS76376.1 - 0.68 9.9 6.9 0.37 10.8 0.7 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Nnf1 PF03980.14 RUS76377.1 - 3.4e-11 43.5 4.4 3.4e-11 43.5 4.4 2.6 2 1 0 2 2 2 1 Nnf1 RasGAP_C PF03836.15 RUS76377.1 - 0.00052 20.2 4.4 0.00052 20.2 4.4 2.8 2 1 1 3 3 3 1 RasGAP C-terminus HsbA PF12296.8 RUS76377.1 - 0.032 14.7 3.3 0.89 10.0 0.1 2.7 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Jnk-SapK_ap_N PF09744.9 RUS76377.1 - 0.25 11.5 19.0 0.087 13.0 11.1 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2433 PF10360.9 RUS76377.1 - 0.31 11.2 5.7 1.3 9.1 5.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) Fib_alpha PF08702.10 RUS76377.1 - 0.63 10.2 16.3 0.12 12.6 4.3 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_14 PF17959.1 RUS76377.1 - 0.81 10.1 5.0 1.2 9.5 0.4 2.6 1 1 2 3 3 3 0 EF-hand domain KIND PF16474.5 RUS76377.1 - 1.7 8.5 8.6 0.72 9.7 6.0 1.7 1 1 1 2 2 2 0 Kinase non-catalytic C-lobe domain Mitofilin PF09731.9 RUS76377.1 - 2.9 6.6 18.0 3.4 6.4 14.5 1.8 1 1 1 2 2 2 0 Mitochondrial inner membrane protein LETM1 PF07766.13 RUS76377.1 - 2.9 7.2 13.8 2.9 7.2 4.0 2.5 1 1 1 2 2 2 0 LETM1-like protein DUF1664 PF07889.12 RUS76377.1 - 3.1 7.8 14.6 1.8 8.6 4.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.8 RUS76377.1 - 5.1 7.5 14.9 2.4 8.5 7.0 2.4 2 0 0 2 2 2 0 YlqD protein PAP2 PF01569.21 RUS76378.1 - 2.4e-28 98.6 1.3 2.4e-28 98.6 1.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RUS76378.1 - 0.019 14.7 8.7 0.88 9.2 8.7 2.6 1 1 0 1 1 1 0 PAP2 superfamily Peptidase_A22B PF04258.13 RUS76378.1 - 0.16 11.5 3.0 0.27 10.7 3.0 1.3 1 0 0 1 1 1 0 Signal peptide peptidase TctA PF01970.16 RUS76378.1 - 0.18 10.5 3.4 0.97 8.1 0.0 2.6 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctA family PAP2_C PF14360.6 RUS76378.1 - 0.41 11.2 11.6 0.52 10.9 2.7 3.0 2 1 0 2 2 2 0 PAP2 superfamily C-terminal NUC173 PF08161.12 RUS76379.1 - 3.8e-66 222.6 5.5 8.6e-64 215.0 0.0 4.2 4 1 0 4 4 4 2 NUC173 domain TIP120 PF08623.10 RUS76379.1 - 0.00097 18.9 0.0 0.00097 18.9 0.0 4.8 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) V-ATPase_H_N PF03224.14 RUS76379.1 - 0.33 10.2 12.5 0.94 8.7 0.9 3.8 4 0 0 4 4 4 0 V-ATPase subunit H DUF4834 PF16118.5 RUS76379.1 - 2.6 9.1 4.6 2.3 9.3 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SRCR PF00530.18 RUS76380.1 - 9.5e-35 119.1 4.1 2.1e-17 63.5 0.1 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS76380.1 - 2.3e-10 40.9 4.6 1.1e-05 25.9 0.4 3.5 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS76380.1 - 0.00069 20.1 0.2 0.54 10.8 0.0 3.3 3 0 0 3 3 3 2 Hepsin, SRCR domain Prominin PF05478.11 RUS76380.1 - 3 5.7 5.4 9.2 4.1 1.4 2.3 2 0 0 2 2 2 0 Prominin GPS2_interact PF15784.5 RUS76382.1 - 1.3e-13 51.2 8.3 3e-13 50.0 8.3 1.7 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain Spc24 PF08286.11 RUS76382.1 - 0.053 13.8 1.8 0.093 13.0 1.8 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SATase_N PF06426.14 RUS76382.1 - 0.11 12.9 0.3 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal YabA PF06156.13 RUS76382.1 - 0.12 13.0 2.4 0.26 11.9 2.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Spectrin PF00435.21 RUS76382.1 - 1.6 9.3 8.4 1.4 9.4 2.3 2.3 2 0 0 2 2 2 0 Spectrin repeat Myb_DNA-bind_6 PF13921.6 RUS76383.1 - 0.01 16.1 0.3 0.01 16.1 0.3 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain FliD_C PF07195.12 RUS76383.1 - 0.018 14.5 1.1 0.023 14.2 1.1 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Myb_DNA-binding PF00249.31 RUS76383.1 - 0.024 14.8 0.8 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain MAM PF00629.23 RUS76383.1 - 0.073 13.0 0.4 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu Myb_DNA-binding PF00249.31 RUS76384.1 - 2.7e-13 49.9 0.7 7.8e-13 48.4 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS76384.1 - 0.0011 19.2 0.3 0.0025 18.0 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4787 PF16029.5 RUS76385.1 - 7.9e-22 77.1 6.4 1.1e-21 76.6 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) adh_short_C2 PF13561.6 RUS76386.1 - 3.8e-39 134.6 0.0 4.5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS76386.1 - 3.3e-29 101.7 0.0 4.6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 RUS76386.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Myb_DNA-bind_6 PF13921.6 RUS76388.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 RUS76388.1 - 0.051 13.8 0.6 0.1 12.8 0.6 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Lipocalin PF00061.23 RUS76388.1 - 0.057 13.6 0.1 0.096 12.9 0.1 1.5 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Sec7 PF01369.20 RUS76389.1 - 6.5e-69 231.3 1.0 2.1e-68 229.6 1.0 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RUS76389.1 - 8.8e-40 136.2 1.5 8.8e-40 136.2 1.5 3.5 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RUS76389.1 - 3.4e-39 134.3 7.3 1.6e-38 132.2 0.5 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 RUS76389.1 - 1.2e-34 118.0 4.8 5.6e-34 115.8 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Cobl PF09469.10 RUS76389.1 - 0.051 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain KH_8 PF17903.1 RUS76390.1 - 9.2e-30 102.6 1.2 3.3e-29 100.8 0.0 2.5 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 RUS76390.1 - 0.083 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 KH domain DUF1450 PF07293.11 RUS76390.1 - 0.46 10.3 1.6 5.2 7.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1450) RBDV_coat PF06593.11 RUS76390.1 - 2.4 7.6 7.1 0.056 12.9 0.8 1.4 2 0 0 2 2 2 0 Raspberry bushy dwarf virus coat protein Tau95 PF09734.9 RUS76390.1 - 4 8.2 12.1 20 6.0 0.0 2.8 1 1 1 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain MbeD_MobD PF04899.12 RUS76391.1 - 0.0028 17.7 3.5 0.96 9.6 0.1 2.4 2 0 0 2 2 2 2 MbeD/MobD like HALZ PF02183.18 RUS76391.1 - 0.006 16.8 1.7 0.34 11.2 0.4 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 RUS76391.1 - 0.044 13.8 1.5 0.044 13.8 1.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3583 PF12126.8 RUS76391.1 - 0.046 13.2 1.6 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) EzrA PF06160.12 RUS76391.1 - 0.07 11.3 7.2 0.27 9.4 1.2 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Spc24 PF08286.11 RUS76391.1 - 0.081 13.2 2.0 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 COMMD1_N PF17221.3 RUS76391.1 - 0.096 13.0 0.2 0.096 13.0 0.2 1.9 2 0 0 2 2 2 0 COMMD1 N-terminal domain DUF4407 PF14362.6 RUS76391.1 - 0.31 10.3 4.7 0.43 9.9 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CHORD PF04968.12 RUS76391.1 - 1 10.1 9.7 2.6 8.8 9.7 1.7 1 1 0 1 1 1 0 CHORD SKA2 PF16740.5 RUS76391.1 - 1.1 9.0 6.7 0.21 11.4 1.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Prefoldin_2 PF01920.20 RUS76391.1 - 1.4 8.9 7.5 2 8.4 0.3 2.7 2 1 1 3 3 3 0 Prefoldin subunit GIT_CC PF16559.5 RUS76391.1 - 2.3 8.2 6.7 0.55 10.1 1.0 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor EMP70 PF02990.16 RUS76392.1 - 6.9e-96 322.0 0.5 8.6e-96 321.6 0.5 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 PIP5K PF01504.18 RUS76392.1 - 0.0051 16.1 0.4 0.0085 15.4 0.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MTA_R1 PF17226.2 RUS76393.1 - 2.8e-29 101.1 3.9 5.5e-28 96.9 1.0 2.4 2 0 0 2 2 2 2 MTA R1 domain MFS_1 PF07690.16 RUS76394.1 - 1e-07 31.2 34.6 9e-05 21.6 18.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily GPHR_N PF12537.8 RUS76394.1 - 0.96 9.6 3.4 1.1 9.4 1.6 2.1 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Lipase PF00151.19 RUS76395.1 - 9.8e-39 133.6 0.1 4.1e-31 108.5 0.1 2.1 2 0 0 2 2 2 2 Lipase Apis_Csd PF11671.8 RUS76395.1 - 0.34 10.9 3.4 0.54 10.3 3.4 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein p450 PF00067.22 RUS76396.1 - 3.5e-94 316.2 0.0 4.2e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCM6_C PF18263.1 RUS76396.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Lectin_C PF00059.21 RUS76397.1 - 3.1e-10 40.8 0.0 2.6e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 RUS76397.1 - 0.00024 21.0 0.3 0.00041 20.2 0.3 1.5 1 0 0 1 1 1 1 PAN domain SAP PF02037.27 RUS76398.1 - 9.5e-15 54.0 1.2 1.6e-14 53.2 1.2 1.4 1 0 0 1 1 1 1 SAP domain SPRY PF00622.28 RUS76398.1 - 2.6e-12 46.9 0.0 6.1e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 SPRY domain PseudoU_synth_1 PF01416.20 RUS76398.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 tRNA pseudouridine synthase BUD22 PF09073.10 RUS76398.1 - 0.055 12.8 35.9 0.074 12.4 35.9 1.1 1 0 0 1 1 1 0 BUD22 HeH PF12949.7 RUS76398.1 - 0.077 12.7 0.3 0.24 11.2 0.2 1.9 1 1 1 2 2 2 0 HeH/LEM domain PROL5-SMR PF15621.6 RUS76398.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Apt1 PF10351.9 RUS76398.1 - 1.1 8.0 11.7 1.7 7.5 11.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM27 PF15832.5 RUS76398.1 - 2.8 8.5 19.7 1.9 9.1 17.7 1.8 1 1 0 1 1 1 0 FAM27 D and E protein family Lin-8 PF03353.15 RUS76398.1 - 6.6 6.2 21.1 10 5.6 21.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mitofilin PF09731.9 RUS76398.1 - 7 5.4 28.6 9.8 4.9 28.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lectin_C PF00059.21 RUS76399.1 - 1.3e-06 29.1 0.2 2.3e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS76399.1 - 0.0024 17.8 1.6 0.0053 16.7 0.3 2.1 2 0 0 2 2 2 1 PAN domain zf-H2C2_2 PF13465.6 RUS76400.1 - 6.9e-52 171.7 58.1 3e-09 36.9 0.5 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76400.1 - 3.2e-36 121.8 60.3 2.5e-05 24.5 0.9 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS76400.1 - 5.9e-26 88.9 60.1 0.00035 21.1 0.8 8.6 9 0 0 9 9 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS76400.1 - 1.3e-17 63.6 28.5 0.00034 20.8 0.5 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS76400.1 - 2e-17 62.7 61.2 0.00069 19.6 2.1 9.9 9 2 0 9 9 9 8 C2H2-type zinc finger zf-met PF12874.7 RUS76400.1 - 1.7e-10 40.9 36.4 0.00025 21.3 1.6 8.3 8 0 0 8 8 8 3 Zinc-finger of C2H2 type Zf_RING PF16744.5 RUS76400.1 - 1.1e-05 25.4 27.8 0.9 9.7 0.1 7.2 1 1 4 6 6 6 2 KIAA1045 RING finger zf_UBZ PF18439.1 RUS76400.1 - 0.00052 19.5 24.1 2.9 7.6 0.1 7.8 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS76400.1 - 0.0008 19.5 26.0 0.44 10.7 0.4 6.0 4 1 2 6 6 6 2 Zinc ribbon domain DUF3268 PF11672.8 RUS76400.1 - 0.00088 19.6 20.3 0.13 12.6 1.1 4.8 3 1 2 5 5 5 3 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 RUS76400.1 - 0.001 19.8 18.3 1.5 9.6 0.4 4.6 1 1 3 5 5 5 2 zinc-ribbon family C1_2 PF03107.16 RUS76400.1 - 0.019 15.3 33.4 4.3 7.7 2.7 7.4 3 2 2 5 5 5 0 C1 domain zf-C2H2_2 PF12756.7 RUS76400.1 - 0.065 13.6 34.5 2.2 8.7 0.2 6.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 RUS76400.1 - 0.067 13.5 12.3 17 5.8 2.1 4.5 3 2 1 4 4 4 0 BolA-like protein FANCI_S3 PF14677.6 RUS76400.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 FYVE PF01363.21 RUS76400.1 - 0.35 11.0 36.6 1.1 9.4 6.7 5.9 2 2 2 4 4 4 0 FYVE zinc finger zf-C2HE PF16278.5 RUS76400.1 - 0.46 11.0 0.0 0.46 11.0 0.0 6.4 2 1 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 RUS76400.1 - 0.49 10.4 0.1 0.49 10.4 0.1 7.0 8 0 0 8 8 8 0 zinc-finger of a C2HC-type GAGA PF09237.11 RUS76400.1 - 0.79 9.6 17.5 1.4 8.8 0.5 6.0 2 1 6 8 8 8 0 GAGA factor Elf1 PF05129.13 RUS76400.1 - 0.85 9.7 23.4 0.37 10.9 0.7 5.2 2 1 3 5 5 5 0 Transcription elongation factor Elf1 like XPA_N PF01286.18 RUS76400.1 - 1.3 9.2 23.0 1.9 8.6 0.0 7.2 8 0 0 8 8 8 0 XPA protein N-terminal zf-HIT PF04438.16 RUS76400.1 - 1.3 8.9 32.1 36 4.4 0.2 7.9 8 0 0 8 8 8 0 HIT zinc finger PHF5 PF03660.14 RUS76400.1 - 1.5 9.0 15.7 4.2 7.6 0.3 4.1 1 1 3 4 4 4 0 PHF5-like protein zf-C2H2_8 PF15909.5 RUS76400.1 - 1.8 8.9 24.9 0.68 10.3 1.6 4.5 2 1 3 5 5 5 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 RUS76400.1 - 1.9 8.4 28.8 2.7 8.0 2.1 6.3 4 3 3 7 7 7 0 SprT-like zinc ribbon domain FpoO PF10621.9 RUS76400.1 - 3.6 7.9 9.9 2.7 8.3 1.9 3.7 1 1 3 4 4 4 0 F420H2 dehydrogenase subunit FpoO zinc-ribbons_6 PF07191.12 RUS76400.1 - 4.2 7.4 23.6 38 4.4 1.1 6.1 2 2 2 4 4 4 0 zinc-ribbons zf-C2H2_9 PF16293.5 RUS76400.1 - 5 7.0 14.9 9.1 6.2 0.2 5.1 6 1 1 7 7 7 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 RUS76400.1 - 5.1 7.8 28.5 5.7 7.6 1.5 6.2 2 1 2 6 6 6 0 Zinc finger C2H2-type, 3 repeats MRPL52 PF18699.1 RUS76401.1 - 2.7e-22 78.8 2.6 4.9e-22 77.9 2.6 1.5 1 0 0 1 1 1 1 Mitoribosomal protein mL52 YqzL PF14006.6 RUS76401.1 - 2.1 8.8 4.4 10 6.6 0.4 2.7 3 0 0 3 3 3 0 YqzL-like protein Ribonuc_L-PSP PF01042.21 RUS76402.1 - 1.8e-40 137.7 0.2 2.1e-40 137.5 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TMEM70 PF06979.12 RUS76403.1 - 0.00042 20.7 0.0 0.00062 20.2 0.0 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF1772 PF08592.11 RUS76403.1 - 0.06 13.7 0.4 0.087 13.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) PDZ_6 PF17820.1 RUS76405.1 - 5.4e-09 35.8 0.1 9.3e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS76405.1 - 5.6e-08 33.0 0.1 9.9e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS76405.1 - 1.7e-05 25.0 0.0 3.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RUS76405.1 - 0.0072 16.3 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pex14_N PF04695.13 RUS76405.1 - 3.2 8.4 8.6 2.2 8.9 3.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OmpH PF03938.14 RUS76405.1 - 5.5 7.3 12.2 8.5 6.7 12.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med13_C PF06333.12 RUS76410.1 - 0.058 12.7 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CAP PF00188.26 RUS76411.1 - 1e-17 65.2 0.1 1.3e-17 64.8 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase_Tyr PF07714.17 RUS76412.1 - 2e-81 273.1 0.0 2.5e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS76412.1 - 4e-38 131.3 0.0 2.6e-36 125.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 RUS76412.1 - 0.00032 20.6 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 RUS76412.1 - 0.0047 17.8 0.0 0.0092 16.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain PAG PF15347.6 RUS76412.1 - 0.015 14.4 0.2 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DAG1 PF05454.11 RUS76412.1 - 0.025 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.11 RUS76412.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Cadherin_C_2 PF16492.5 RUS76412.1 - 0.062 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF5305 PF17231.2 RUS76412.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) UPF0560 PF10577.9 RUS76412.1 - 0.07 11.6 0.0 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Haspin_kinase PF12330.8 RUS76412.1 - 0.095 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 RUS76415.1 - 2.2e-17 62.6 0.1 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 RUS76415.1 - 0.00048 18.5 38.8 0.00048 18.5 38.8 2.2 2 0 0 2 2 2 1 Nop14-like family RRM_7 PF16367.5 RUS76415.1 - 0.0036 17.4 0.0 0.36 11.0 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 RUS76415.1 - 0.0036 17.3 0.5 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Limkain b1 RRM_Rrp7 PF17799.1 RUS76415.1 - 0.012 15.4 1.3 0.063 13.1 0.1 2.7 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain BUD22 PF09073.10 RUS76415.1 - 0.013 14.8 102.3 0.087 12.2 49.2 2.3 2 0 0 2 2 2 0 BUD22 DUF3456 PF11938.8 RUS76416.1 - 2.7e-11 44.2 0.3 8e-11 42.7 0.3 1.8 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP COesterase PF00135.28 RUS76418.1 - 5.6e-77 259.8 0.0 7.6e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS76418.1 - 1.7e-06 28.1 1.4 0.02 14.8 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ank_4 PF13637.6 RUS76419.1 - 6.4e-10 39.4 0.3 8.9e-05 23.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS76419.1 - 5.9e-07 30.0 0.1 8.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS76419.1 - 7.5e-06 25.9 0.5 0.00034 20.8 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RUS76419.1 - 0.0013 19.0 0.4 0.0059 16.9 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS76419.1 - 0.0017 18.8 0.1 0.0096 16.3 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeat Gly_transf_sug PF04488.15 RUS76420.1 - 1.1e-09 38.8 0.1 2.4e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS76420.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_transf_8 PF01501.20 RUS76420.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 TcdA_TcdB PF12919.7 RUS76420.1 - 0.0026 17.1 0.5 0.004 16.5 0.5 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.15 RUS76421.1 - 1.8e-09 38.1 0.1 4.3e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS76421.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 RUS76421.1 - 0.0034 16.8 0.7 0.0051 16.1 0.7 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_8 PF01501.20 RUS76421.1 - 0.0048 16.5 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Arm PF00514.23 RUS76422.1 - 3.6e-45 150.7 21.1 4.3e-07 29.7 0.0 11.1 11 0 0 11 11 11 6 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 RUS76422.1 - 2.4e-32 112.3 0.8 9.8e-31 107.0 0.6 3.1 2 1 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 RUS76422.1 - 5.2e-25 87.7 16.7 5.6e-05 23.5 0.1 7.2 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.22 RUS76422.1 - 3.6e-16 57.9 15.7 0.073 13.4 0.0 9.1 9 0 0 9 9 8 5 HEAT repeat HEAT_EZ PF13513.6 RUS76422.1 - 2.7e-15 56.5 18.3 0.021 15.3 0.0 8.6 8 0 0 8 8 8 4 HEAT-like repeat Cnd1 PF12717.7 RUS76422.1 - 2.8e-12 47.0 12.0 7.1e-05 22.9 0.0 5.7 3 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 RUS76422.1 - 6.7e-11 42.3 1.0 0.0026 17.9 0.0 5.4 3 2 4 7 7 7 3 V-ATPase subunit H Arm_2 PF04826.13 RUS76422.1 - 4.2e-10 39.5 5.1 6.5e-06 25.8 0.6 3.4 2 2 1 3 3 3 2 Armadillo-like WAPL PF07814.13 RUS76422.1 - 4.3e-07 29.1 5.6 0.11 11.3 0.1 4.0 2 2 1 3 3 3 3 Wings apart-like protein regulation of heterochromatin Adaptin_N PF01602.20 RUS76422.1 - 2.5e-06 26.4 4.4 0.005 15.5 1.1 3.4 2 2 0 3 3 3 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 RUS76422.1 - 0.0007 19.6 2.6 0.85 9.7 0.2 3.9 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 RUS76422.1 - 0.00098 18.5 0.3 0.15 11.3 0.1 3.2 2 2 0 2 2 2 1 V-ATPase subunit H DUF3385 PF11865.8 RUS76422.1 - 0.018 15.0 0.0 23 4.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) TetR_C_36 PF18598.1 RUS76422.1 - 0.066 13.2 0.7 7.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DRIM PF07539.12 RUS76422.1 - 0.18 10.0 2.2 14 3.8 0.0 3.0 3 0 0 3 3 3 0 Down-regulated in metastasis DUF5578 PF17741.1 RUS76422.1 - 0.21 11.0 1.9 3.8 6.9 0.1 3.5 3 1 1 4 4 4 0 Family of unknown function (DUF5578) Apt1 PF10351.9 RUS76422.1 - 0.45 9.3 8.9 0.82 8.5 8.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 RUS76422.1 - 0.58 8.9 12.4 0.96 8.1 12.4 1.2 1 0 0 1 1 1 0 Presenilin RasGEF_N_2 PF14663.6 RUS76422.1 - 0.71 10.3 9.6 7.2 7.1 0.0 5.4 5 2 2 7 7 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Aconitase_B_N PF11791.8 RUS76422.1 - 0.88 9.6 3.6 6.6 6.8 0.0 4.0 5 0 0 5 5 5 0 Aconitate B N-terminal domain eIF3_subunit PF08597.10 RUS76422.1 - 3.5 7.5 29.7 0.028 14.3 18.6 2.5 3 0 0 3 3 2 0 Translation initiation factor eIF3 subunit HEAT_PBS PF03130.16 RUS76422.1 - 3.8 8.5 11.0 79 4.4 0.0 6.4 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat SOBP PF15279.6 RUS76422.1 - 5.3 7.6 8.1 11 6.6 8.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Smg8_Smg9 PF10220.9 RUS76422.1 - 6.3 5.0 9.5 8.9 4.5 9.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 RUS76422.1 - 9.9 4.8 10.3 8.6 5.0 6.2 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-BED PF02892.15 RUS76423.1 - 2e-08 34.1 4.7 3.7e-08 33.3 4.7 1.5 1 0 0 1 1 1 1 BED zinc finger OrsD PF12013.8 RUS76423.1 - 0.0091 16.4 1.9 0.025 15.0 1.9 1.7 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D HSD3 PF15244.6 RUS76424.1 - 9.2e-38 130.8 18.6 1.9e-24 87.0 11.2 5.8 4 2 0 4 4 4 2 Spermatogenesis-associated protein 7, or HSD3 DUF1677 PF07911.13 RUS76424.1 - 0.097 13.1 0.0 14 6.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) ANAPC_CDC26 PF10471.9 RUS76425.1 - 2.7 8.9 8.7 0.21 12.4 2.5 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 adh_short PF00106.25 RUS76426.1 - 1.2e-17 64.1 0.3 1.1e-16 60.9 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS76426.1 - 2.9e-07 30.3 0.0 4.2e-05 23.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS76426.1 - 2.1e-06 27.8 0.1 3.5e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Omptin PF01278.20 RUS76426.1 - 0.01 14.9 0.1 0.01 14.9 0.1 1.4 2 0 0 2 2 2 1 Omptin family TIR PF01582.20 RUS76426.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 TIR domain ATP-synt_F PF01990.17 RUS76426.1 - 0.091 13.1 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit LIF_OSM PF01291.17 RUS76426.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 LIF / OSM family Ribosomal_L34 PF00468.17 RUS76427.1 - 0.01 15.8 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L34 PID PF00640.23 RUS76428.1 - 2.6e-36 124.7 0.0 3.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 RUS76428.1 - 3e-13 49.7 0.0 5.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain Adipokin_hormo PF06377.11 RUS76429.1 - 0.00014 22.1 2.8 0.0015 18.8 2.8 2.2 1 1 0 1 1 1 1 Adipokinetic hormone 7tm_1 PF00001.21 RUS76430.1 - 5.8e-32 111.1 3.2 6.8e-32 110.8 3.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) IGFBP PF00219.18 RUS76431.1 - 2.2e-08 34.6 23.2 2.2e-08 34.6 23.2 4.4 2 1 1 3 3 3 1 Insulin-like growth factor binding protein SDA1 PF05285.12 RUS76432.1 - 0.0013 18.3 32.0 0.0016 17.9 32.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS76432.1 - 0.057 11.6 37.1 0.082 11.1 37.1 1.1 1 0 0 1 1 1 0 Nop14-like family Glycophorin_A PF01102.18 RUS76432.1 - 0.17 12.1 1.1 0.31 11.3 1.1 1.4 1 0 0 1 1 1 0 Glycophorin A SAPS PF04499.15 RUS76432.1 - 3.3 6.4 10.0 5.2 5.7 10.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein adh_short PF00106.25 RUS76433.1 - 5.3e-33 114.1 0.2 7.4e-33 113.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS76433.1 - 7.2e-28 97.7 0.0 9.7e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS76433.1 - 0.003 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Mpv17_PMP22 PF04117.12 RUS76434.1 - 1.5e-17 63.5 0.5 3.4e-17 62.4 0.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mt_ATP-synt_B PF05405.14 RUS76435.1 - 4.7 6.8 10.9 12 5.5 10.9 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cas_Cas02710 PF09670.10 RUS76436.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DDE_Tnp_1_7 PF13843.6 RUS76436.1 - 0.068 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 Mtc PF03820.17 RUS76439.1 - 3.3e-122 407.4 0.3 3.7e-122 407.3 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier BAR_3_WASP_bdg PF10456.9 RUS76441.1 - 0.0082 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Baculo_PEP_C PF04513.12 RUS76441.1 - 0.021 14.9 0.8 0.048 13.7 0.7 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.12 RUS76441.1 - 0.06 12.8 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tropomyosin_1 PF12718.7 RUS76441.1 - 0.14 12.3 0.8 0.55 10.4 0.2 1.9 2 0 0 2 2 2 0 Tropomyosin like Fuseless PF15993.5 RUS76442.1 - 4e-12 45.9 1.8 5.6e-12 45.5 1.8 1.1 1 0 0 1 1 1 1 Fuseless Rpn3_C PF08375.11 RUS76443.1 - 3.4e-29 101.1 1.7 3.4e-29 101.1 1.7 1.8 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 RUS76443.1 - 4.4e-24 85.0 0.0 1.7e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 RUS76443.1 - 0.0055 16.7 0.8 0.0055 16.7 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Pro-MCH PF05824.12 RUS76443.1 - 0.15 12.0 1.3 0.57 10.1 1.1 2.0 1 1 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) RT_RNaseH PF17917.1 RUS76445.1 - 0.014 15.7 0.4 0.093 13.0 0.0 2.6 2 2 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RisS_PPD PF16524.5 RUS76445.1 - 0.12 12.7 0.1 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Pyr_redox_2 PF07992.14 RUS76446.1 - 3.5e-57 193.9 0.5 4.5e-57 193.5 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RUS76446.1 - 9.4e-30 103.1 0.1 1.7e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RUS76446.1 - 2.1e-19 69.8 0.5 3.7e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS76446.1 - 3.1e-14 53.0 0.5 5.5e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS76446.1 - 3.5e-08 32.9 0.7 2.8e-07 30.0 0.5 2.4 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 RUS76446.1 - 1.2e-07 31.2 1.4 5.5e-07 29.0 1.4 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 RUS76446.1 - 4.2e-05 23.1 6.0 0.00023 20.6 5.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 RUS76446.1 - 0.00011 21.9 4.3 0.0018 17.9 0.6 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS76446.1 - 0.00028 19.7 0.2 0.00028 19.7 0.2 2.0 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 RUS76446.1 - 0.00032 20.1 1.0 0.00064 19.1 0.3 1.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RUS76446.1 - 0.0013 18.0 0.2 0.0032 16.8 0.2 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 RUS76446.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 RUS76446.1 - 0.16 11.1 0.3 14 4.7 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 RUS76446.1 - 0.8 8.7 3.0 0.39 9.7 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Glutaredoxin PF00462.24 RUS76447.1 - 9.6e-09 35.3 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 RUS76447.1 - 0.029 14.8 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 RUS76447.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Ig_3 PF13927.6 RUS76448.1 - 1.1e-07 32.3 0.6 0.0092 16.6 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS76448.1 - 3.8e-05 23.7 0.1 0.0053 16.8 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 RUS76448.1 - 0.00017 21.7 0.2 0.21 11.8 0.1 4.1 2 2 1 3 3 3 1 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS76448.1 - 0.00045 20.5 0.2 0.028 14.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain PAX PF00292.18 RUS76449.1 - 4.4e-64 214.0 0.3 7.1e-64 213.4 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 RUS76449.1 - 0.072 12.9 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain RFX_DNA_binding PF02257.15 RUS76450.1 - 0.00072 20.1 0.6 0.14 12.8 0.0 2.8 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.16 RUS76450.1 - 0.0012 19.3 11.1 0.2 12.1 0.1 4.6 4 0 0 4 4 4 2 Poxvirus D5 protein-like TFIIA PF03153.13 RUS76450.1 - 0.027 14.5 11.0 0.042 13.8 11.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L18_c PF14204.6 RUS76450.1 - 7 7.7 9.1 1.9 9.5 0.9 3.3 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region Ribosomal_L2_C PF03947.18 RUS76451.1 - 4.2e-24 85.1 0.4 1.1e-23 83.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RUS76451.1 - 9.6e-18 63.9 0.5 1.9e-17 63.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_C12 PF01088.21 RUS76452.1 - 1.5e-67 227.5 0.0 3.2e-67 226.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 RUS76452.1 - 1.4e-16 60.1 0.4 3.4e-16 58.9 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases EF-hand_7 PF13499.6 RUS76454.1 - 3.7e-05 24.1 0.2 0.00012 22.4 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS76454.1 - 0.0074 16.1 0.1 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS76454.1 - 0.16 11.6 0.3 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 EF hand Arrestin_N PF00339.29 RUS76455.1 - 3.3e-24 85.6 0.1 4.5e-23 81.9 0.0 2.7 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS76455.1 - 5.5e-21 75.4 0.3 3.7e-17 63.1 0.0 3.2 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS76455.1 - 0.0002 20.7 0.6 0.047 12.9 0.1 3.1 4 0 0 4 4 4 2 Rgp1 Vps26 PF03643.15 RUS76455.1 - 0.0004 19.5 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Spo0M PF07070.11 RUS76455.1 - 0.19 11.3 0.0 0.76 9.3 0.0 1.8 2 0 0 2 2 2 0 SpoOM protein FGE-sulfatase PF03781.16 RUS76456.1 - 2.6e-30 105.9 0.8 2.9e-30 105.7 0.8 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 G6PD_C PF02781.16 RUS76457.1 - 1.9e-115 385.0 0.0 2.6e-115 384.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RUS76457.1 - 4.7e-59 200.0 0.0 8.2e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RabGAP-TBC PF00566.18 RUS76459.1 - 3.8e-51 173.8 2.2 5.8e-51 173.2 2.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TSP_1 PF00090.19 RUS76460.1 - 2.1e-36 123.9 47.6 7.3e-11 42.1 11.5 4.2 4 0 0 4 4 4 4 Thrombospondin type 1 domain DUF483 PF04467.12 RUS76460.1 - 0.53 10.3 1.9 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF483) TSP_1 PF00090.19 RUS76461.1 - 1.1e-09 38.3 33.2 2e-05 24.7 11.5 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain CARD PF00619.21 RUS76462.1 - 1.4e-08 34.6 0.1 3.9e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Caspase recruitment domain Death PF00531.22 RUS76462.1 - 1.5e-07 31.5 0.1 1.5e-05 25.1 0.1 2.3 2 0 0 2 2 2 2 Death domain DUF5582 PF17819.1 RUS76463.1 - 1.8e-06 28.5 0.0 3.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) EF-hand_7 PF13499.6 RUS76463.1 - 0.00015 22.1 0.0 0.064 13.7 0.0 1.7 1 1 1 2 2 2 2 EF-hand domain pair DUF5586 PF17824.1 RUS76463.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5586) EF-hand_6 PF13405.6 RUS76463.1 - 0.0055 16.5 0.0 0.018 15.0 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS76463.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2151 PF10221.9 RUS76464.1 - 1.5e-60 205.6 0.0 1.7e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator CdiI_N PF18228.1 RUS76464.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 CdiI N-terminal domain ASC PF00858.24 RUS76465.1 - 1.6e-86 291.0 2.9 2.2e-86 290.6 2.9 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2151 PF10221.9 RUS76466.1 - 2.3e-56 191.8 0.0 2.5e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator UBA_4 PF14555.6 RUS76467.1 - 6.1e-13 48.4 0.0 8.8e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain AAA_assoc_2 PF16193.5 RUS76467.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA C-terminal domain UCH_1 PF13423.6 RUS76469.1 - 1.5e-97 327.1 5.0 1.5e-97 327.1 5.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 RUS76469.1 - 9.4e-19 68.6 0.0 4.1e-18 66.5 0.0 2.2 2 0 0 2 2 2 1 Exonuclease ANAPC4_WD40 PF12894.7 RUS76469.1 - 0.11 12.9 0.0 5.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS76469.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A zf-CCCH_2 PF14608.6 RUS76469.1 - 0.43 11.1 9.2 1.1 9.8 9.2 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CDC45 PF02724.14 RUS76469.1 - 1.5 7.0 7.0 2.8 6.1 7.0 1.3 1 0 0 1 1 1 0 CDC45-like protein OB_NTP_bind PF07717.16 RUS76470.1 - 8.3e-26 90.2 0.0 2.2e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RUS76470.1 - 2.3e-23 82.5 0.3 2.3e-23 82.5 0.3 3.5 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RUS76470.1 - 4.4e-14 52.8 0.0 1.5e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 RUS76470.1 - 3.5e-11 43.3 0.1 3.5e-11 43.3 0.1 2.1 2 0 0 2 2 1 1 S1 RNA binding domain DEAD PF00270.29 RUS76470.1 - 2.6e-06 27.3 0.1 7e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS76470.1 - 9.3e-05 22.7 0.1 0.00026 21.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RUS76470.1 - 0.0036 16.4 0.9 0.009 15.1 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 RUS76470.1 - 0.005 17.2 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS76470.1 - 0.012 16.0 0.2 0.045 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RSRP PF17069.5 RUS76470.1 - 0.014 15.0 33.0 0.029 14.0 33.0 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 AAA_30 PF13604.6 RUS76470.1 - 0.028 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RUS76470.1 - 0.12 11.8 0.2 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 RUS76470.1 - 0.29 11.7 4.9 0.28 11.7 0.3 3.1 2 2 0 2 2 2 0 ABC transporter Spem1 PF15670.5 RUS76470.1 - 1.8 8.1 11.1 4.1 6.9 11.1 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1201 PF06716.11 RUS76472.1 - 0.0044 17.0 1.6 0.0077 16.2 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) LMBR1 PF04791.16 RUS76473.1 - 0.0096 14.9 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein UPF0220 PF05255.11 RUS76473.1 - 0.027 14.0 0.1 0.049 13.2 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) FPN1 PF06963.12 RUS76473.1 - 0.041 12.5 1.0 0.062 11.9 1.0 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) HisKA_7TM PF16927.5 RUS76473.1 - 4.2 7.4 7.2 0.83 9.6 2.1 2.1 2 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase RNase_H PF00075.24 RUS76474.1 - 2.8e-14 53.5 0.0 9.3e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS76474.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Ribosomal_L22e PF01776.17 RUS76474.1 - 0.12 12.7 0.2 0.9 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L22e protein family XPG_I PF00867.18 RUS76475.1 - 2.4e-18 66.3 0.0 5.7e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RUS76475.1 - 5.8e-09 36.3 0.0 1.7e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Chromo_2 PF18704.1 RUS76475.1 - 7.3e-06 26.2 0.2 1.6e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 Atx10homo_assoc PF09759.9 RUS76476.1 - 8.3e-07 29.0 17.0 1.6e-05 24.9 2.0 5.2 2 1 3 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 RUS76476.1 - 0.00016 21.6 4.6 6.4 7.0 0.0 5.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 RUS76476.1 - 0.00025 21.0 4.5 0.0058 16.6 0.3 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) Rif1_N PF12231.8 RUS76476.1 - 0.26 10.2 3.5 0.087 11.8 0.3 1.7 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal PARP PF00644.20 RUS76477.1 - 2.2e-24 86.2 0.2 3.8e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 RUS76477.1 - 1.1e-13 51.2 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain LicD PF04991.13 RUS76478.1 - 1.5e-16 61.2 5.1 3.5e-13 50.2 2.5 2.1 1 1 1 2 2 2 2 LicD family PAP2 PF01569.21 RUS76479.1 - 1.4e-14 54.0 4.0 1.4e-14 54.0 4.0 2.5 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 RUS76479.1 - 2.1e-05 24.3 5.4 2.1e-05 24.3 5.4 2.5 3 1 0 3 3 3 1 PAP2 superfamily Myotub-related PF06602.14 RUS76480.1 - 1.3e-150 501.2 0.2 1.9e-150 500.7 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 RUS76480.1 - 2.1e-14 53.4 0.0 5.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 RUS76480.1 - 0.00071 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 RUS76480.1 - 0.0012 18.6 1.3 0.0089 15.8 0.4 2.5 2 0 0 2 2 2 1 Myotubularin-associated protein DSPc PF00782.20 RUS76480.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS76480.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HMMR_N PF15905.5 RUS76482.1 - 0.00023 20.8 45.7 0.11 12.0 14.1 3.2 1 1 1 3 3 3 3 Hyaluronan mediated motility receptor N-terminal HAD_2 PF13419.6 RUS76482.1 - 0.0033 17.5 2.6 0.0033 17.5 2.6 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase ADIP PF11559.8 RUS76482.1 - 0.022 14.8 51.4 0.036 14.1 6.8 4.9 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.12 RUS76482.1 - 0.05 13.9 9.9 0.93 9.8 0.1 4.2 2 1 0 3 3 3 0 Proteins of 100 residues with WXG HAP1_N PF04849.13 RUS76482.1 - 0.06 12.6 49.1 0.035 13.3 5.5 3.5 1 1 1 3 3 3 0 HAP1 N-terminal conserved region GTP-bdg_M PF16360.5 RUS76482.1 - 0.076 13.6 0.2 0.076 13.6 0.2 3.6 3 1 0 3 3 3 0 GTP-binding GTPase Middle Region CENP-F_leu_zip PF10473.9 RUS76482.1 - 0.079 13.0 52.3 1.7 8.7 15.2 4.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T7SS_ESX_EspC PF10824.8 RUS76482.1 - 0.082 13.4 0.5 42 4.7 0.0 3.4 3 1 1 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm ATG16 PF08614.11 RUS76482.1 - 0.095 12.9 41.7 0.28 11.4 8.5 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RUS76482.1 - 0.13 12.7 46.3 0.51 10.8 9.7 3.7 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 RUS76482.1 - 0.18 11.8 20.7 1.5 8.9 1.6 4.3 1 1 3 4 4 4 0 Laminin Domain II Golgin_A5 PF09787.9 RUS76482.1 - 0.19 11.1 46.2 1.5 8.2 35.7 3.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 RUS76482.1 - 0.31 11.7 0.2 0.31 11.7 0.2 6.1 3 2 3 6 6 6 0 SlyX ACCA PF03255.14 RUS76482.1 - 0.43 10.5 23.1 0.27 11.1 1.4 4.1 2 2 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4164 PF13747.6 RUS76482.1 - 0.92 9.8 32.9 0.99 9.7 5.8 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) Filament PF00038.21 RUS76482.1 - 0.95 9.0 43.2 0.56 9.7 6.3 4.0 1 1 3 4 4 4 0 Intermediate filament protein DUF1664 PF07889.12 RUS76482.1 - 1.1 9.3 25.7 0.4 10.7 5.6 4.2 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RUS76482.1 - 3 7.9 47.8 0.36 10.9 18.5 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 RUS76482.1 - 3 8.3 13.9 26 5.3 0.1 5.4 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RUS76482.1 - 3.2 8.1 8.3 37 4.7 0.5 4.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.11 RUS76482.1 - 5 7.2 15.5 0.23 11.5 2.4 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1515) DUF1216 PF06746.11 RUS76483.1 - 0.0014 18.6 2.6 0.0014 18.6 2.6 2.1 1 1 1 2 2 1 1 Protein of unknown function (DUF1216) DHHW PF14286.6 RUS76483.1 - 0.02 14.2 2.3 0.024 13.9 2.3 1.0 1 0 0 1 1 1 0 DHHW protein DUF3552 PF12072.8 RUS76483.1 - 0.034 13.6 4.8 0.043 13.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) UPF0242 PF06785.11 RUS76483.1 - 0.036 14.2 1.9 0.049 13.7 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA1 PF07160.12 RUS76483.1 - 0.044 13.6 2.6 0.048 13.5 2.6 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Atg14 PF10186.9 RUS76483.1 - 0.053 12.6 9.8 0.056 12.5 9.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 RUS76483.1 - 0.056 12.3 5.6 0.06 12.2 5.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tnp_22_trimer PF17489.2 RUS76483.1 - 0.057 13.4 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain Use1 PF09753.9 RUS76483.1 - 0.086 12.5 3.5 0.096 12.4 3.5 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Allexi_40kDa PF05549.11 RUS76483.1 - 0.26 10.8 3.4 0.29 10.6 3.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1117 PF06547.12 RUS76483.1 - 0.29 11.7 7.0 0.31 11.6 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) BBP1_C PF15272.6 RUS76483.1 - 0.32 10.8 9.7 0.46 10.3 9.7 1.3 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Chorion_2 PF03964.15 RUS76483.1 - 0.45 11.4 11.0 0.57 11.0 11.0 1.2 1 0 0 1 1 1 0 Chorion family 2 Herpes_pp85 PF04637.12 RUS76483.1 - 0.65 8.3 10.9 0.67 8.3 10.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CDK2AP PF09806.9 RUS76483.1 - 0.94 9.5 7.4 1.1 9.3 7.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 RUS76483.1 - 1.3 8.8 10.8 1.6 8.5 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) HIP1_clath_bdg PF16515.5 RUS76483.1 - 1.5 9.5 6.8 2.7 8.6 6.8 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CCDC106 PF15794.5 RUS76483.1 - 2 8.1 12.4 2.3 7.9 12.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SARAF PF06682.12 RUS76483.1 - 2.2 7.8 8.0 2.5 7.7 8.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PI3K_1B_p101 PF10486.9 RUS76483.1 - 2.8 5.6 11.7 3.1 5.5 11.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.13 RUS76483.1 - 8.6 4.3 28.3 8.5 4.3 28.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RSRP PF17069.5 RUS76483.1 - 8.6 5.8 24.9 9.7 5.7 24.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 7tm_1 PF00001.21 RUS76484.1 - 1e-43 149.6 0.9 1.1e-43 149.5 0.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS76484.1 - 2.8e-08 33.8 2.2 1.7e-07 31.3 3.4 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS76484.1 - 6.9e-07 29.2 6.0 1.5e-06 28.1 6.0 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS76484.1 - 1.4e-06 27.9 3.6 4.4e-06 26.3 2.8 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx SR-25 PF10500.9 RUS76485.1 - 0.00033 20.3 32.1 0.00049 19.8 32.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YfhO PF09586.10 RUS76485.1 - 0.0004 18.8 8.2 0.0004 18.8 8.2 2.1 1 1 1 2 2 1 1 Bacterial membrane protein YfhO CBP_BcsG PF11658.8 RUS76485.1 - 0.00068 18.2 3.8 0.00068 18.2 3.8 2.7 1 1 1 2 2 1 1 Cellulose biosynthesis protein BcsG DOCK_N PF16172.5 RUS76485.1 - 0.0016 17.5 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 DOCK N-terminus FAM176 PF14851.6 RUS76485.1 - 0.0051 16.5 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 FAM176 family DUF2852 PF11014.8 RUS76485.1 - 0.0058 16.8 0.1 0.0058 16.8 0.1 2.1 2 1 0 2 2 1 1 Protein of unknown function (DUF2852) Myc_target_1 PF15179.6 RUS76485.1 - 0.01 15.8 0.4 0.01 15.8 0.4 2.7 2 1 0 2 2 1 0 Myc target protein 1 TRAP_alpha PF03896.16 RUS76485.1 - 0.035 13.3 0.1 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SspB PF04386.13 RUS76485.1 - 0.048 13.5 1.3 0.072 13.0 1.3 1.2 1 0 0 1 1 1 0 Stringent starvation protein B HA2 PF04408.23 RUS76485.1 - 0.051 13.9 4.2 0.11 12.8 4.2 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF2828 PF11443.8 RUS76485.1 - 0.057 11.5 9.4 0.071 11.2 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rtf2 PF04641.12 RUS76485.1 - 0.064 12.6 21.4 0.091 12.1 21.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger G0-G1_switch_2 PF15103.6 RUS76485.1 - 0.065 13.7 5.0 0.12 12.8 5.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 CPSF100_C PF13299.6 RUS76485.1 - 0.068 13.4 7.7 0.097 12.9 7.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1764 PF08576.10 RUS76485.1 - 0.074 13.9 20.7 0.12 13.3 20.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DDHD PF02862.17 RUS76485.1 - 0.086 13.0 4.2 0.12 12.5 4.2 1.1 1 0 0 1 1 1 0 DDHD domain Miga PF10265.9 RUS76485.1 - 0.096 11.6 6.7 0.13 11.2 6.7 1.1 1 0 0 1 1 1 0 Mitoguardin Jak1_Phl PF17887.1 RUS76485.1 - 0.12 12.4 11.6 0.22 11.5 11.6 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF755 PF05501.11 RUS76485.1 - 0.12 12.7 32.9 0.22 11.8 32.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TMEM214 PF10151.9 RUS76485.1 - 0.15 10.5 21.5 0.21 10.0 21.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Eapp_C PF10238.9 RUS76485.1 - 0.2 11.7 14.4 0.32 11.1 14.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein AIF_C PF14721.6 RUS76485.1 - 0.23 11.8 8.2 0.45 10.9 8.2 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RPN2_C PF18004.1 RUS76485.1 - 0.32 10.9 22.6 0.49 10.3 22.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 RUS76485.1 - 0.4 10.1 12.6 0.55 9.6 12.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RPOL_N PF14700.6 RUS76485.1 - 0.44 9.9 12.4 0.61 9.4 12.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF3807 PF12720.7 RUS76485.1 - 0.45 10.8 18.8 0.67 10.2 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.8 RUS76485.1 - 1.1 8.0 13.6 1.4 7.6 13.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LicD PF04991.13 RUS76485.1 - 1.2 9.3 14.4 1.6 8.8 14.4 1.2 1 0 0 1 1 1 0 LicD family Vfa1 PF08432.10 RUS76485.1 - 1.3 9.4 26.2 1.9 8.8 26.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Gti1_Pac2 PF09729.9 RUS76485.1 - 1.3 9.1 15.0 2 8.5 15.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DNApol_Exo PF18136.1 RUS76485.1 - 1.6 7.8 12.6 2.3 7.3 12.6 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Afi1 PF07792.12 RUS76485.1 - 1.7 9.1 10.4 2.6 8.5 10.4 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GAGA_bind PF06217.12 RUS76485.1 - 1.8 8.8 19.9 2.4 8.3 19.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family ORC_WH_C PF18137.1 RUS76485.1 - 1.9 8.6 11.3 2.9 8.0 11.3 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal eIF3_subunit PF08597.10 RUS76485.1 - 2 8.3 27.1 2.8 7.8 27.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4551 PF15087.6 RUS76485.1 - 2.2 7.0 12.9 3 6.6 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NPR3 PF03666.13 RUS76485.1 - 3.4 6.4 18.6 4.6 5.9 18.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4228 PF14009.6 RUS76485.1 - 3.9 7.8 9.6 5.4 7.4 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF4770 PF15994.5 RUS76485.1 - 4.4 7.5 16.0 7.9 6.7 16.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) PPL5 PF18168.1 RUS76485.1 - 4.9 6.4 13.3 6.6 5.9 13.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 RUS76485.1 - 5.3 6.8 18.5 10 5.8 18.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 RUS76485.1 - 5.7 7.4 17.1 8.3 6.8 17.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 MMU163 PF17119.5 RUS76485.1 - 7.5 5.6 10.6 11 5.1 10.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis PcfK PF14058.6 RUS76485.1 - 7.6 6.8 25.0 12 6.2 25.0 1.2 1 0 0 1 1 1 0 PcfK-like protein V_ATPase_I PF01496.19 RUS76485.1 - 8.2 4.2 25.9 7.3 4.4 24.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 RUS76485.1 - 8.3 5.2 25.6 11 4.8 25.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GNAT_acetyltr_2 PF13718.6 RUS76485.1 - 8.5 5.7 8.0 12 5.2 8.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Baculo_PEP_C PF04513.12 RUS76486.1 - 0.00032 20.7 36.1 0.12 12.4 4.0 6.7 2 2 4 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 RUS76486.1 - 0.00064 19.9 14.5 0.00064 19.9 14.5 7.3 2 1 5 7 7 7 4 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 RUS76486.1 - 0.00066 20.0 117.7 0.11 12.7 10.8 8.7 2 1 6 8 8 8 5 Autophagy protein 16 (ATG16) Filament PF00038.21 RUS76486.1 - 0.034 13.7 99.7 0.2 11.2 9.2 7.8 2 1 5 8 8 8 0 Intermediate filament protein PatG_C PF18065.1 RUS76486.1 - 0.042 13.8 1.3 0.58 10.1 0.1 3.0 2 0 0 2 2 2 0 PatG C-terminal DUF1664 PF07889.12 RUS76486.1 - 0.067 13.2 60.3 0.21 11.6 1.5 8.9 2 1 7 9 9 9 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 RUS76486.1 - 0.47 9.4 72.3 0.072 12.1 3.9 5.9 2 1 3 6 6 6 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 RUS76486.1 - 1.3 9.1 106.0 0.06 13.4 9.7 8.2 2 1 5 8 8 8 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 RUS76486.1 - 3.2 7.1 103.8 0.019 14.5 20.4 5.8 2 1 4 6 6 6 0 Golgin subfamily A member 5 DUF5631 PF18645.1 RUS76486.1 - 5.9 7.3 7.3 14 6.1 0.0 4.5 3 1 3 6 6 6 0 Family of unknown function (DUF5631) Hydrolase_4 PF12146.8 RUS76488.1 - 8.5e-08 31.7 0.1 0.00042 19.6 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 RUS76488.1 - 4e-06 26.7 0.0 8.1e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 RUS76488.1 - 0.0014 19.3 3.9 0.3 11.6 3.8 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RUS76488.1 - 0.0038 16.7 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RUS76488.1 - 0.0059 16.3 1.3 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 RUS76488.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 RUS76488.1 - 0.018 14.8 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 RUS76488.1 - 0.025 13.6 0.0 0.066 12.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 RUS76488.1 - 0.05 12.5 0.1 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF346 PF03984.13 RUS76488.1 - 0.057 13.2 1.3 0.13 12.0 0.3 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Esterase_phd PF10503.9 RUS76488.1 - 0.071 12.6 0.2 0.24 10.9 0.2 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF2381 PF09544.10 RUS76488.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF4735 PF15882.5 RUS76489.1 - 1.2e-68 231.7 1.7 5.2e-58 196.8 1.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4735) Spec3 PF15795.5 RUS76490.1 - 3e-16 59.7 4.2 4.8e-16 59.1 4.2 1.3 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein DHHC PF01529.20 RUS76490.1 - 0.077 13.1 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase NicO PF03824.16 RUS76490.1 - 0.077 12.3 3.7 0.044 13.1 0.9 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein ASC PF00858.24 RUS76491.1 - 1.4e-92 311.0 6.0 2.3e-92 310.3 6.0 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel PBECR1 PF18809.1 RUS76491.1 - 0.017 15.8 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 CedA PF10729.9 RUS76491.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Cell division activator CedA ASC PF00858.24 RUS76492.1 - 8.7e-29 100.8 0.6 9.7e-29 100.6 0.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS76493.1 - 1.2e-48 166.2 4.5 4.3e-48 164.4 4.5 1.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Glyco_transf_8 PF01501.20 RUS76494.1 - 2.8e-49 168.0 0.0 4.8e-49 167.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RUS76494.1 - 3.9e-07 29.8 0.0 1.2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Glucosyltransferase 24 bZIP_2 PF07716.15 RUS76495.1 - 1.9e-17 63.1 13.2 2.9e-17 62.5 13.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS76495.1 - 4.9e-05 23.3 8.6 8e-05 22.7 8.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS76495.1 - 0.049 14.1 6.6 0.096 13.2 6.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 RUS76495.1 - 0.2 10.1 9.3 0.29 9.7 9.3 1.2 1 0 0 1 1 1 0 Macoilin family AC_N PF16214.5 RUS76495.1 - 9.6 5.2 6.0 22 4.0 6.0 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region OATP PF03137.20 RUS76496.1 - 1.4e-85 287.7 15.4 4.6e-85 286.0 15.4 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS76496.1 - 8.7e-11 41.3 38.3 3.9e-06 26.0 14.2 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS76496.1 - 0.00015 21.8 2.1 0.00015 21.8 2.1 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain ATG22 PF11700.8 RUS76496.1 - 0.00032 19.4 8.9 0.054 12.1 1.2 2.8 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like PUCC PF03209.15 RUS76496.1 - 0.0098 14.9 1.0 0.0098 14.9 1.0 2.6 3 0 0 3 3 3 1 PUCC protein MFS_4 PF06779.14 RUS76496.1 - 0.028 13.7 0.3 0.028 13.7 0.3 3.2 3 1 2 5 5 5 0 Uncharacterised MFS-type transporter YbfB Kazal_1 PF00050.21 RUS76496.1 - 1.6 8.8 4.5 0.91 9.6 1.7 1.9 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain RRM_1 PF00076.22 RUS76497.1 - 1.8e-32 111.0 0.0 4.9e-21 74.3 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS76497.1 - 3.2e-09 36.8 0.0 0.003 17.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 RUS76497.1 - 7.1e-06 25.9 0.9 0.15 11.8 0.0 3.7 2 1 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 RUS76497.1 - 9.5e-05 22.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 RUS76497.1 - 0.00011 22.1 0.0 0.057 13.4 0.0 2.5 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RUS76497.1 - 0.11 12.4 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif SIP1 PF04938.12 RUS76497.1 - 1.7 8.3 8.5 0.11 12.2 3.0 1.7 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) MULE PF10551.9 RUS76498.1 - 3.3e-08 33.8 0.3 1.2e-07 32.0 0.1 2.1 2 0 0 2 2 1 1 MULE transposase domain SDA1 PF05285.12 RUS76498.1 - 9.8e-07 28.5 21.6 1.3e-06 28.1 21.6 1.2 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 RUS76498.1 - 7.3e-06 25.0 20.7 7.7e-06 24.9 20.7 1.2 1 0 0 1 1 1 1 Caldesmon Mpp10 PF04006.12 RUS76498.1 - 7.8e-06 24.6 29.1 1e-05 24.2 29.1 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 RUS76498.1 - 4.7e-05 22.9 22.1 6.7e-05 22.4 22.1 1.2 1 0 0 1 1 1 1 BUD22 DUF913 PF06025.12 RUS76498.1 - 0.00017 20.7 8.3 0.00028 20.0 8.3 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 RUS76498.1 - 0.00054 19.9 18.1 0.00078 19.4 18.1 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 RUS76498.1 - 0.0032 17.0 13.2 0.0059 16.1 13.2 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 RUS76498.1 - 0.0033 17.6 3.8 0.0048 17.1 3.8 1.4 1 0 0 1 1 1 1 DDHD domain SpoIIIAH PF12685.7 RUS76498.1 - 0.0035 17.2 13.0 0.014 15.2 12.7 1.9 2 0 0 2 2 2 1 SpoIIIAH-like protein DUF2254 PF10011.9 RUS76498.1 - 0.0052 15.6 0.3 0.021 13.7 0.3 1.9 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) Pes-10 PF07149.11 RUS76498.1 - 0.0076 15.4 31.6 0.014 14.5 31.6 1.5 1 0 0 1 1 1 1 Pes-10 CLN3 PF02487.17 RUS76498.1 - 0.03 13.4 3.4 0.043 12.8 3.4 1.3 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 RUS76498.1 - 0.035 12.3 10.9 0.043 12.0 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.15 RUS76498.1 - 0.037 13.6 17.9 0.052 13.1 13.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PTPRCAP PF15713.5 RUS76498.1 - 0.039 14.2 33.6 0.071 13.4 33.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4045 PF13254.6 RUS76498.1 - 0.045 13.4 10.5 0.055 13.1 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 RUS76498.1 - 0.049 12.9 7.8 0.059 12.6 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Na_trans_assoc PF06512.13 RUS76498.1 - 0.055 13.8 20.7 0.088 13.1 20.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 RUS76498.1 - 0.063 11.6 27.6 0.096 11.0 27.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 RUS76498.1 - 0.1 12.3 10.9 0.2 11.4 10.9 1.5 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 RUS76498.1 - 0.1 11.0 2.8 0.13 10.6 2.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 RUS76498.1 - 0.14 11.1 7.8 0.19 10.7 7.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 RUS76498.1 - 0.16 12.4 12.1 0.26 11.7 12.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 RUS76498.1 - 0.18 11.0 10.8 0.37 10.0 10.8 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF2828 PF11443.8 RUS76498.1 - 0.2 9.7 10.3 0.055 11.6 7.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF5308 PF17233.2 RUS76498.1 - 0.22 11.8 1.9 0.37 11.0 1.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Coilin_N PF15862.5 RUS76498.1 - 0.24 11.2 11.3 0.56 10.0 11.3 1.7 1 0 0 1 1 1 0 Coilin N-terminus PIP5K PF01504.18 RUS76498.1 - 0.3 10.3 4.8 0.47 9.6 4.8 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCDC53 PF10152.9 RUS76498.1 - 0.3 11.5 13.3 0.6 10.5 13.3 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Raftlin PF15250.6 RUS76498.1 - 0.34 9.6 11.6 0.48 9.1 11.6 1.2 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 RUS76498.1 - 0.36 9.5 16.9 0.52 9.0 16.9 1.1 1 0 0 1 1 1 0 Presenilin Cytomega_UL84 PF06284.11 RUS76498.1 - 0.38 9.2 19.0 0.27 9.6 5.4 2.0 1 1 1 2 2 2 0 Cytomegalovirus UL84 protein FAM60A PF15396.6 RUS76498.1 - 0.39 10.7 5.4 0.75 9.8 5.4 1.5 1 0 0 1 1 1 0 Protein Family FAM60A CCSAP PF15748.5 RUS76498.1 - 0.44 10.7 18.7 0.85 9.7 18.7 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Gti1_Pac2 PF09729.9 RUS76498.1 - 0.5 10.4 7.5 1.1 9.4 7.5 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Astro_capsid_p PF12226.8 RUS76498.1 - 0.51 9.5 25.2 0.82 8.8 25.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 RUS76498.1 - 0.62 8.1 47.3 1.1 7.2 47.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 RUS76498.1 - 0.67 9.6 33.6 1.3 8.7 33.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Sec62 PF03839.16 RUS76498.1 - 0.81 9.2 10.8 1.4 8.4 10.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Paramyxo_ncap PF00973.19 RUS76498.1 - 0.82 8.5 4.9 1.2 8.0 4.9 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.10 RUS76498.1 - 1.2 9.5 22.1 2.2 8.6 22.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MID_MedPIWI PF18296.1 RUS76498.1 - 1.4 8.7 4.8 2.1 8.1 4.8 1.4 1 0 0 1 1 1 0 MID domain of medPIWI Ycf1 PF05758.12 RUS76498.1 - 1.8 6.3 10.3 2.8 5.7 10.3 1.3 1 0 0 1 1 1 0 Ycf1 PA26 PF04636.13 RUS76498.1 - 1.8 7.4 11.1 2.5 6.9 11.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HSP90 PF00183.18 RUS76498.1 - 1.8 7.3 31.2 3.6 6.4 31.2 1.5 1 0 0 1 1 1 0 Hsp90 protein Serinc PF03348.15 RUS76498.1 - 2.3 7.1 6.6 3.2 6.6 6.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CSRNP_N PF16019.5 RUS76498.1 - 2.9 7.7 11.5 5.8 6.8 11.5 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CENP-N PF05238.13 RUS76498.1 - 3.3 6.9 10.7 1.1 8.5 7.4 1.8 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Spore_coat_CotO PF14153.6 RUS76498.1 - 5.2 7.0 28.2 10 6.0 28.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.8 RUS76498.1 - 7.3 5.3 25.7 2.9 6.6 22.8 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FGF-BP1 PF06473.12 RUS76498.1 - 7.5 6.3 16.3 13 5.5 16.3 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF3306 PF11748.8 RUS76498.1 - 8.1 7.3 20.2 27 5.7 20.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) LRR_8 PF13855.6 RUS76499.1 - 1.4e-22 79.2 9.6 1.9e-14 53.2 1.2 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS76499.1 - 3.9e-09 36.6 9.4 0.0066 16.8 0.5 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS76499.1 - 5.4e-07 29.6 0.0 9.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS76499.1 - 9.7e-07 28.5 3.9 3.8 8.4 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat Ldl_recept_a PF00057.18 RUS76499.1 - 2.4e-05 24.5 47.7 0.00016 21.8 9.4 4.8 2 1 1 4 4 4 3 Low-density lipoprotein receptor domain class A LRRNT PF01462.18 RUS76499.1 - 0.00046 19.8 5.9 0.0018 17.8 0.2 3.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 RUS76499.1 - 0.00073 19.1 2.7 0.04 13.4 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 RUS76499.1 - 0.41 10.8 22.6 4.6 7.5 0.2 6.4 7 0 0 7 7 7 0 Leucine Rich repeat 7tm_1 PF00001.21 RUS76500.1 - 1.6e-19 70.3 11.7 2.1e-19 69.9 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS76500.1 - 0.00013 21.4 9.3 0.0002 20.8 9.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS76500.1 - 0.0012 18.5 6.4 0.0012 18.5 6.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Fibrinogen_C PF00147.18 RUS76501.1 - 3.2e-29 102.3 3.4 3.8e-29 102.1 3.4 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS76502.1 - 7.3e-05 22.7 1.1 0.00014 21.8 0.7 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Chordopox_L2 PF05803.12 RUS76502.1 - 0.043 13.6 0.6 0.093 12.6 0.6 1.5 1 0 0 1 1 1 0 Chordopoxvirus L2 protein FAM76 PF16046.5 RUS76502.1 - 0.11 11.9 2.9 0.26 10.6 2.9 1.7 1 0 0 1 1 1 0 FAM76 protein YojJ PF10372.9 RUS76502.1 - 0.6 10.2 4.2 8.8 6.5 0.4 3.3 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF5492 PF17596.2 RUS76502.1 - 1.1 9.6 19.8 48 4.4 3.9 5.0 1 1 1 2 2 2 0 Family of unknown function (DUF5492) FlxA PF14282.6 RUS76502.1 - 1.2 9.2 9.1 2.1 8.4 7.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Fzo_mitofusin PF04799.13 RUS76502.1 - 8 6.0 7.4 1.1 8.7 1.6 2.4 1 1 2 3 3 3 0 fzo-like conserved region JAB PF01398.21 RUS76503.1 - 7.6e-32 109.8 0.0 1.4e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RUS76503.1 - 1.4e-14 54.4 0.8 2.4e-14 53.7 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 RUS76503.1 - 2.3e-06 27.3 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1959 PF09218.10 RUS76503.1 - 0.092 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) XendoU PF09412.10 RUS76503.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU Gtr1_RagA PF04670.12 RUS76505.1 - 4.6e-72 242.1 3.4 5.7e-72 241.8 3.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 RUS76505.1 - 4.3e-06 26.3 0.0 6.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS76505.1 - 4e-05 23.8 0.0 6.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS76505.1 - 8.1e-05 22.3 0.2 0.00012 21.7 0.2 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS76505.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS76505.1 - 0.00021 20.9 0.1 0.00032 20.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS76505.1 - 0.00029 20.9 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS76505.1 - 0.005 17.2 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 RUS76505.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4573 PF15140.6 RUS76506.1 - 1.5e-12 47.7 41.8 5e-11 42.7 16.9 3.7 2 1 1 3 3 3 3 Domain of unknown function (DUF4573) Claudin_2 PF13903.6 RUS76508.1 - 4.1e-15 56.0 2.8 5.1e-15 55.7 2.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 RUS76508.1 - 0.0026 17.2 7.0 0.31 10.5 7.0 2.4 1 1 0 1 1 1 1 Clc-like Claudin_3 PF06653.11 RUS76508.1 - 0.0056 16.6 2.9 0.0056 16.6 2.9 1.8 2 0 0 2 2 2 1 Tight junction protein, Claudin-like MARVEL PF01284.23 RUS76508.1 - 0.018 15.1 0.1 0.018 15.1 0.1 2.2 3 0 0 3 3 3 0 Membrane-associating domain DUF418 PF04235.12 RUS76508.1 - 0.047 13.6 0.7 0.047 13.6 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF418) Ser_hydrolase PF06821.13 RUS76508.1 - 0.1 12.5 0.0 7.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase TctB PF07331.11 RUS76508.1 - 0.11 12.7 5.0 0.31 11.3 3.1 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Ni_hydr_CYTB PF01292.20 RUS76508.1 - 0.56 9.8 6.8 6.4 6.3 0.1 2.6 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 RRM_1 PF00076.22 RUS76509.1 - 1.8e-16 59.7 0.3 4.3e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS76509.1 - 1.2e-05 24.9 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RUS76509.1 - 0.042 14.0 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain Pkinase_Tyr PF07714.17 RUS76511.1 - 1.4e-07 31.1 0.0 1.5e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS76511.1 - 0.00033 20.1 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 RUS76512.1 - 1.7e-20 73.5 0.0 2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76512.1 - 2.5e-20 72.9 0.0 2.8e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS76512.1 - 0.00046 19.6 0.2 0.00063 19.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RUS76512.1 - 0.018 14.4 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS76512.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.4 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 RUS76512.1 - 0.022 14.7 0.1 0.023 14.6 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family V-ATPase_H_N PF03224.14 RUS76514.1 - 7.8e-94 314.5 8.3 7.8e-94 314.5 8.3 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 RUS76514.1 - 4.6e-46 155.7 2.6 1.4e-45 154.2 0.1 2.8 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 RUS76514.1 - 3.7e-06 26.6 0.3 2.8e-05 23.7 0.0 2.3 2 1 1 3 3 3 1 Armadillo-like DUF1474 PF07342.11 RUS76514.1 - 0.0023 18.4 0.8 0.011 16.3 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1474) CENP-K PF11802.8 RUS76514.1 - 0.0059 16.2 6.4 0.028 14.0 1.6 2.5 2 1 0 2 2 2 2 Centromere-associated protein K RIH_assoc PF08454.11 RUS76514.1 - 0.32 10.9 2.0 5.1 7.0 0.3 2.9 2 1 0 2 2 2 0 RyR and IP3R Homology associated OATP PF03137.20 RUS76515.1 - 2.8e-33 115.0 14.9 4.3e-33 114.4 4.6 2.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS76515.1 - 0.00035 19.6 4.4 0.00035 19.6 4.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_Ag35 PF03286.14 RUS76515.1 - 0.0068 16.2 1.5 0.0098 15.7 1.5 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.11 RUS76515.1 - 0.038 12.1 1.8 0.05 11.7 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 RUS76515.1 - 0.1 12.3 1.4 0.16 11.6 1.4 1.3 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 RUS76515.1 - 0.15 12.6 6.9 0.15 12.7 5.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 RUS76515.1 - 2.5 6.1 5.4 5.8 4.9 3.2 1.9 2 0 0 2 2 2 0 DNA polymerase phi zf-U1 PF06220.12 RUS76516.1 - 0.0037 17.0 0.6 0.012 15.3 0.2 2.0 2 0 0 2 2 2 1 U1 zinc finger TPR_1 PF00515.28 RUS76517.1 - 2.1e-26 90.6 4.0 0.00096 18.9 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76517.1 - 3.1e-25 86.2 4.2 0.00012 21.9 0.0 8.4 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS76517.1 - 3.5e-17 62.7 1.9 0.00032 21.3 0.1 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76517.1 - 7.5e-14 51.1 4.8 0.0005 19.7 0.0 5.5 5 1 0 5 5 5 3 TPR repeat TPR_19 PF14559.6 RUS76517.1 - 2.1e-13 50.5 0.3 4.2e-06 27.2 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76517.1 - 7.6e-12 44.5 5.8 0.38 11.1 0.0 7.1 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RUS76517.1 - 6.3e-10 39.0 0.3 0.12 13.3 0.0 5.4 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS76517.1 - 6.2e-09 36.0 5.5 0.51 10.7 0.0 6.0 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76517.1 - 8e-09 35.3 2.4 4.4 7.9 0.0 7.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76517.1 - 7e-08 32.6 1.3 0.075 13.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS76517.1 - 2.1e-07 31.0 1.2 0.3 11.3 0.1 3.8 3 1 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RUS76517.1 - 0.001 18.9 0.1 26 5.1 0.0 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 RUS76517.1 - 0.0021 18.2 2.3 7.4 6.8 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS76517.1 - 0.0083 15.5 1.1 0.26 10.6 0.0 2.9 2 1 1 3 3 3 2 MalT-like TPR region TPR_10 PF13374.6 RUS76517.1 - 0.03 14.2 0.1 7.9 6.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 RUS76517.1 - 0.099 13.0 0.3 4.7 7.6 0.1 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPPII_N PF12583.8 RUS76517.1 - 0.11 13.0 0.1 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Homeodomain PF00046.29 RUS76518.1 - 1.3e-19 69.8 2.4 1.3e-19 69.8 2.4 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS76518.1 - 0.017 15.1 1.3 0.021 14.7 0.0 1.8 2 0 0 2 2 2 0 Homeobox KN domain AAA_33 PF13671.6 RUS76519.1 - 6.5e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS76519.1 - 0.00018 22.1 0.1 0.00068 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 RUS76519.1 - 0.0017 17.7 0.3 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 RUS76519.1 - 0.034 14.5 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 RUS76519.1 - 0.074 12.5 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF3450 PF11932.8 RUS76519.1 - 1.6 8.0 7.6 3.2 7.0 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Hyd_WA PF06462.12 RUS76520.1 - 4e-37 125.9 19.6 9.3e-08 31.9 0.7 8.0 8 0 0 8 8 8 6 Propeller ANAPC4_WD40 PF12894.7 RUS76520.1 - 0.0044 17.3 0.1 0.14 12.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain I-set PF07679.16 RUS76521.1 - 1.7e-14 53.6 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS76521.1 - 7.1e-13 49.0 0.1 2.7e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain EGF PF00008.27 RUS76521.1 - 1.3e-09 38.2 30.9 0.00034 20.8 4.7 3.9 3 0 0 3 3 3 3 EGF-like domain ig PF00047.25 RUS76521.1 - 3.1e-09 36.9 0.0 8.8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS76521.1 - 1.3e-05 25.4 0.0 4.7e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain EGF_2 PF07974.13 RUS76521.1 - 0.00014 22.2 40.5 0.092 13.1 8.8 3.6 3 0 0 3 3 3 3 EGF-like domain NtA PF03146.15 RUS76521.1 - 0.0002 21.2 0.0 0.00055 19.8 0.0 1.7 2 0 0 2 2 2 1 Agrin NtA domain hEGF PF12661.7 RUS76521.1 - 0.0007 20.1 23.0 0.65 10.7 3.5 4.6 3 2 0 3 3 3 3 Human growth factor-like EGF V-set PF07686.17 RUS76521.1 - 0.016 15.3 0.0 0.2 11.8 0.0 2.4 1 1 0 1 1 1 0 Immunoglobulin V-set domain cEGF PF12662.7 RUS76521.1 - 2.1 8.4 18.7 0.87 9.6 1.7 4.2 4 0 0 4 4 4 0 Complement Clr-like EGF-like Macro PF01661.21 RUS76522.1 - 5.8e-35 119.9 2.1 6.2e-35 119.8 0.2 1.9 2 0 0 2 2 2 1 Macro domain DHHA1 PF02272.19 RUS76522.1 - 0.0091 16.4 0.3 0.02 15.3 0.3 1.5 1 0 0 1 1 1 1 DHHA1 domain STAC2_u1 PF16664.5 RUS76522.1 - 0.045 14.2 5.4 0.075 13.5 5.4 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 CCDC106 PF15794.5 RUS76522.1 - 0.075 12.7 8.3 0.11 12.2 8.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TMEM215 PF15746.5 RUS76522.1 - 0.25 10.8 3.9 0.38 10.2 3.9 1.3 1 0 0 1 1 1 0 TMEM215 family POX PF07526.11 RUS76522.1 - 5.3 7.6 8.7 8.3 7.0 8.5 1.4 1 1 0 1 1 1 0 Associated with HOX 7tm_2 PF00002.24 RUS76523.1 - 2.4e-24 86.0 16.3 3.9e-24 85.3 16.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) adh_short PF00106.25 RUS76525.1 - 1e-33 116.5 0.0 1.6e-32 112.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS76525.1 - 1.7e-20 73.6 0.0 1.6e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS76525.1 - 9.7e-08 32.1 0.0 2.8e-07 30.6 0.0 1.7 1 1 1 2 2 2 1 KR domain DNA_pol_lambd_f PF10391.9 RUS76525.1 - 0.54 10.1 2.3 5.3 6.9 0.0 3.2 5 0 0 5 5 5 0 Fingers domain of DNA polymerase lambda Tweety PF04906.13 RUS76526.1 - 0.00071 18.4 0.4 0.0011 17.7 0.4 1.2 1 0 0 1 1 1 1 Tweety TSC22 PF01166.18 RUS76526.1 - 0.021 15.1 2.2 0.048 14.0 0.7 2.3 2 1 1 3 3 3 0 TSC-22/dip/bun family BLOC1_2 PF10046.9 RUS76526.1 - 0.15 12.4 1.1 0.37 11.1 1.1 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DDHD PF02862.17 RUS76527.1 - 3.6 7.7 5.8 4.7 7.3 5.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF1068 PF06364.12 RUS76527.1 - 5 7.0 15.1 7.4 6.4 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) ADH_zinc_N PF00107.26 RUS76528.1 - 1.4e-21 76.8 0.0 3.7e-21 75.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS76528.1 - 1.8e-09 38.8 0.0 4.2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS76528.1 - 3.9e-06 26.7 0.1 9.8e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 RUS76528.1 - 0.0019 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain PGM_PMM_II PF02879.16 RUS76528.1 - 0.011 16.3 0.0 0.037 14.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FMN_red PF03358.15 RUS76528.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase RVT_1 PF00078.27 RUS76529.1 - 6.2e-08 32.4 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BESS PF02944.20 RUS76529.1 - 1.7e-05 24.5 0.2 4.6e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 BESS motif DUF5384 PF17358.2 RUS76529.1 - 0.064 13.3 0.4 0.064 13.3 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5384) bZIP_2 PF07716.15 RUS76529.1 - 1.5 9.0 17.2 0.42 10.7 4.2 3.1 3 0 0 3 3 3 0 Basic region leucine zipper DUF423 PF04241.15 RUS76530.1 - 3.5e-22 78.4 0.3 5.1e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) zf-RAG1 PF10426.9 RUS76530.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Fibrinogen_C PF00147.18 RUS76531.1 - 2.5e-48 164.8 4.4 4.6e-48 163.9 4.4 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CLZ PF16526.5 RUS76531.1 - 0.0017 18.7 4.1 0.08 13.3 1.4 3.0 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Apolipoprotein PF01442.18 RUS76531.1 - 0.033 14.1 5.3 0.076 12.9 4.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 RUS76531.1 - 0.046 14.2 3.9 0.54 10.8 1.2 2.9 2 1 1 3 3 3 0 Spectrin repeat Baculo_PEP_C PF04513.12 RUS76531.1 - 0.11 12.5 10.2 0.18 11.8 0.2 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad3 PF08656.10 RUS76531.1 - 0.3 11.2 9.4 0.11 12.6 2.4 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad3 FAM76 PF16046.5 RUS76531.1 - 0.61 9.4 6.2 0.095 12.0 0.6 2.1 1 1 0 2 2 2 0 FAM76 protein T3SS_basalb_I PF17001.5 RUS76531.1 - 0.95 10.1 4.2 2.7 8.6 0.4 3.1 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Occludin_ELL PF07303.13 RUS76531.1 - 1.6 9.5 4.2 17 6.2 0.2 3.7 1 1 4 5 5 5 0 Occludin homology domain Atg14 PF10186.9 RUS76531.1 - 4.2 6.3 11.2 0.31 10.1 3.9 2.4 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha_E1_glycop PF01589.16 RUS76532.1 - 0.038 12.6 0.7 0.049 12.3 0.7 1.2 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein Chromadorea_ALT PF05535.12 RUS76532.1 - 0.63 10.3 5.7 7.8 6.8 1.6 2.6 2 0 0 2 2 2 0 Chromadorea ALT protein SSF PF00474.17 RUS76533.1 - 2e-40 138.9 23.8 2.6e-40 138.6 23.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 RUS76534.1 - 1.1e-37 129.9 26.8 1.4e-37 129.5 26.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family PPP4R2 PF09184.11 RUS76534.1 - 0.0016 18.1 7.0 0.002 17.8 7.0 1.2 1 0 0 1 1 1 1 PPP4R2 DUF4022 PF13214.6 RUS76534.1 - 0.085 13.1 0.3 0.085 13.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4022) 7tm_1 PF00001.21 RUS76535.1 - 1.3e-49 168.9 1.1 1.7e-49 168.6 1.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS76535.1 - 2.4e-06 27.2 3.5 2.4e-06 27.2 3.5 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS76535.1 - 2.6e-06 27.3 9.2 5.5e-06 26.2 9.2 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS76535.1 - 0.0014 18.4 3.7 0.8 9.4 0.3 2.5 3 0 0 3 3 3 2 Olfactory receptor EZH2_WD-Binding PF11616.8 RUS76535.1 - 0.086 13.0 0.4 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 WD repeat binding protein EZH2 NMU PF02070.15 RUS76536.1 - 8.2e-07 28.8 12.2 2.4 8.1 0.0 5.3 5 0 0 5 5 5 4 Neuromedin U DUF4934 PF16288.5 RUS76536.1 - 1.5 8.8 5.3 12 5.8 0.1 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4934) ABC_tran PF00005.27 RUS76537.1 - 1.4e-51 174.6 0.1 1.2e-28 100.3 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 RUS76537.1 - 1.1e-43 149.9 34.5 3.1e-25 89.4 5.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RUS76537.1 - 6.4e-08 32.3 0.0 0.0095 15.4 0.1 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS76537.1 - 2e-05 24.6 0.0 0.057 13.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS76537.1 - 2.8e-05 24.1 0.7 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RUS76537.1 - 0.00017 21.7 3.7 0.0026 17.8 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 RUS76537.1 - 0.00052 20.4 0.1 1.3 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 RUS76537.1 - 0.0026 17.6 0.0 3.2 7.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS76537.1 - 0.0039 16.9 0.4 0.37 10.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RUS76537.1 - 0.089 12.5 0.2 0.19 11.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 RUS76537.1 - 0.14 11.3 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 RUS76537.1 - 0.17 12.4 0.0 9.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 RUS76537.1 - 0.17 12.1 0.4 7.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_membrane_3 PF13748.6 RUS76537.1 - 0.17 11.1 7.7 0.45 9.7 1.7 2.8 2 0 0 2 2 2 0 ABC transporter transmembrane region UPF0093 PF03653.13 RUS76537.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) SbcCD_C PF13558.6 RUS76537.1 - 0.22 11.8 1.8 45 4.4 0.2 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RUS76537.1 - 1.7 9.1 7.7 9.3 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain Ycf66_N PF07444.11 RUS76537.1 - 2.8 8.2 12.0 0.14 12.3 2.2 2.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus Ribonucleas_3_3 PF14622.6 RUS76538.1 - 1.2e-41 141.9 2.4 1.8e-22 79.9 0.0 3.8 4 0 0 4 4 4 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RUS76538.1 - 3.8e-39 133.5 0.1 2.8e-18 66.5 0.0 3.5 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 RUS76538.1 - 4.9e-11 43.2 0.0 2.2e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Nop14 PF04147.12 RUS76540.1 - 2 6.5 61.0 2.2 6.4 43.7 2.0 2 0 0 2 2 2 0 Nop14-like family adh_short_C2 PF13561.6 RUS76541.1 - 2.6e-41 141.7 0.1 7.1e-28 97.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS76541.1 - 5.6e-37 127.1 0.6 8e-37 126.6 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS76541.1 - 1.1e-09 38.4 0.1 1.9e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RUS76541.1 - 0.0045 16.2 0.2 0.0062 15.7 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 RUS76541.1 - 0.0051 16.1 0.2 0.032 13.6 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RUS76541.1 - 0.026 14.6 0.1 0.048 13.7 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 RUS76541.1 - 0.099 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain RasGEF PF00617.19 RUS76542.1 - 1.1e-48 165.8 2.7 1.4e-48 165.4 1.4 1.8 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 RUS76542.1 - 2e-05 25.1 0.0 4.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF3492 PF11997.8 RUS76542.1 - 0.00028 20.7 0.1 0.00056 19.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) TBCC_N PF16752.5 RUS76542.1 - 2.9 8.3 5.5 1.8 9.0 0.0 2.6 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain MBR1 PF17058.5 RUS76544.1 - 0.066 13.5 9.3 0.1 12.9 9.3 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 LETM1 PF07766.13 RUS76544.1 - 0.31 10.4 2.3 0.31 10.3 0.2 1.8 1 1 1 2 2 2 0 LETM1-like protein Alpha-2-MRAP_C PF06401.11 RUS76544.1 - 1.3 8.9 5.1 0.17 11.8 0.9 1.5 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DHHC PF01529.20 RUS76545.1 - 2.8e-25 89.0 9.0 2.8e-25 89.0 9.0 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Holin_BhlA PF10960.8 RUS76545.1 - 0.18 11.8 1.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 BhlA holin family WW PF00397.26 RUS76546.1 - 6.2e-13 48.6 2.1 6.2e-13 48.6 2.1 1.8 2 0 0 2 2 2 1 WW domain SSF PF00474.17 RUS76547.1 - 3.6e-29 101.9 27.9 5.5e-29 101.2 27.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Holin_BhlA PF10960.8 RUS76550.1 - 0.022 14.7 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 BhlA holin family SCIMP PF15050.6 RUS76550.1 - 0.028 14.9 0.0 0.064 13.7 0.0 1.6 1 1 0 1 1 1 0 SCIMP protein EphA2_TM PF14575.6 RUS76550.1 - 0.061 14.2 0.0 0.11 13.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS76550.1 - 0.087 13.1 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3169 PF11368.8 RUS76550.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Pkinase PF00069.25 RUS76551.1 - 8.6e-31 107.3 0.0 9.8e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76551.1 - 5.9e-19 68.4 0.0 5.9e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS76551.1 - 8.3e-07 28.1 0.0 1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS76551.1 - 0.037 13.3 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RUS76551.1 - 0.079 12.3 0.3 0.12 11.7 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRP68 PF16969.5 RUS76553.1 - 4.2e-155 517.9 6.0 5.1e-155 517.7 6.0 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 MIT PF04212.18 RUS76553.1 - 0.01 15.8 2.6 0.031 14.4 0.2 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain FliS PF02561.14 RUS76553.1 - 0.012 15.9 5.1 4.9 7.5 0.1 4.1 4 0 0 4 4 4 0 Flagellar protein FliS TPR_1 PF00515.28 RUS76553.1 - 0.02 14.7 1.6 5.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76553.1 - 0.024 15.2 5.1 0.48 11.2 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76553.1 - 0.066 13.4 3.8 9.3 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS76553.1 - 2.8 8.3 9.2 4.7 7.6 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Imm65 PF15582.6 RUS76554.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 65 Nop14 PF04147.12 RUS76555.1 - 0.012 13.9 20.1 0.015 13.6 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS76555.1 - 0.07 11.2 40.2 0.01 14.0 36.6 1.3 2 0 0 2 2 2 0 DNA polymerase phi SDA1 PF05285.12 RUS76555.1 - 0.35 10.3 21.7 0.43 10.0 21.7 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS76555.1 - 0.81 8.1 17.3 0.99 7.8 17.3 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RUS76555.1 - 0.83 7.9 18.6 1 7.6 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 RUS76555.1 - 1 9.2 19.8 1.7 8.5 19.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 RUS76555.1 - 1.5 8.3 18.3 2.2 7.8 18.3 1.3 1 0 0 1 1 1 0 PPP4R2 USP7_ICP0_bdg PF12436.8 RUS76556.1 - 3.7e-78 262.2 0.0 1.7e-77 260.0 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 RUS76556.1 - 4.9e-70 235.4 7.8 3.6e-69 232.6 5.2 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 RUS76556.1 - 2.7e-47 161.5 0.2 4.5e-47 160.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS76556.1 - 1.2e-19 71.1 0.5 1.5e-18 67.5 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 RUS76556.1 - 1.3e-17 64.0 0.1 6.8e-17 61.7 0.1 2.3 2 0 0 2 2 2 1 MATH domain EphA2_TM PF14575.6 RUS76557.1 - 0.0072 17.2 0.0 0.018 15.9 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 RUS76557.1 - 0.054 13.1 0.8 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Gram_pos_anchor PF00746.21 RUS76557.1 - 0.056 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FeoB_associated PF12669.7 RUS76557.1 - 0.11 12.9 0.5 0.23 11.9 0.5 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TNFR_16_TM PF18422.1 RUS76557.1 - 0.2 11.7 1.0 0.34 10.9 1.0 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain ADH_zinc_N PF00107.26 RUS76558.1 - 5.4e-26 91.1 0.2 1.2e-25 89.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS76558.1 - 1e-24 86.5 4.7 2.3e-24 85.4 4.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 RUS76558.1 - 6.3e-12 45.4 0.2 9.5e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RUS76558.1 - 3.7e-11 44.2 0.1 1.7e-10 42.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RUS76558.1 - 2.2e-05 23.9 0.7 3.7e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 RUS76558.1 - 0.00032 20.2 0.2 0.00046 19.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RUS76558.1 - 0.00038 21.1 0.2 0.0017 19.0 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 RUS76558.1 - 0.0021 17.7 0.3 0.0038 16.8 0.3 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS76558.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 RUS76558.1 - 0.033 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 RUS76558.1 - 0.034 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 RUS76558.1 - 0.059 12.1 0.4 0.084 11.6 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein FtsJ PF01728.19 RUS76558.1 - 0.06 13.5 0.0 0.097 12.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase YbjQ_1 PF01906.17 RUS76558.1 - 0.16 12.6 0.2 21 5.8 0.1 2.8 2 1 1 3 3 3 0 Putative heavy-metal-binding Cyclin_N PF00134.23 RUS76559.1 - 1.3e-22 79.9 0.1 5.2e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS76559.1 - 1.9e-14 53.8 0.1 5.3e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box-like PF12937.7 RUS76559.1 - 3.9e-05 23.4 0.4 8.3e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS76559.1 - 0.00022 21.0 0.4 0.00063 19.6 0.4 1.7 1 0 0 1 1 1 1 F-box domain YL1 PF05764.13 RUS76559.1 - 0.021 15.0 1.8 0.034 14.3 1.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pyr_redox_3 PF13738.6 RUS76560.1 - 3.6e-34 118.4 0.0 4.8e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS76560.1 - 2.2e-09 37.0 0.0 4.8e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS76560.1 - 8.7e-07 28.4 0.0 1.9e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RUS76560.1 - 7.3e-05 22.9 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RUS76560.1 - 0.00023 20.0 0.0 0.1 11.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 RUS76560.1 - 0.0015 18.2 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS76560.1 - 0.0033 18.0 0.0 3.1 8.4 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RUS76560.1 - 0.0033 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 RUS76560.1 - 0.0047 15.4 0.0 0.04 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 RUS76560.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 RUS76560.1 - 0.14 11.4 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DUF2612 PF11041.8 RUS76560.1 - 0.21 11.5 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) DUF4515 PF14988.6 RUS76562.1 - 4.5e-20 72.4 31.0 4.5e-20 72.4 31.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) DUF4618 PF15397.6 RUS76562.1 - 0.0018 17.7 31.3 0.0026 17.2 31.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 RUS76562.1 - 0.016 15.2 36.5 0.49 10.4 22.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 kleA_kleC PF17383.2 RUS76562.1 - 0.74 10.2 7.0 1.8 9.0 0.8 2.6 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A GAS PF13851.6 RUS76562.1 - 3 7.1 41.7 7.7 5.8 24.3 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3112 PF11309.8 RUS76562.1 - 3.1 7.2 4.7 0.49 9.8 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) ApoO PF09769.9 RUS76562.1 - 3.9 7.4 8.5 1.9 8.4 2.3 2.3 1 1 1 2 2 2 0 Apolipoprotein O Spc7 PF08317.11 RUS76562.1 - 6.8 5.5 34.8 1.8 7.4 15.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Acylphosphatase PF00708.18 RUS76562.1 - 7.9 7.0 7.9 0.93 9.9 0.6 2.5 3 0 0 3 3 3 0 Acylphosphatase K_channel_TID PF07941.11 RUS76563.1 - 1.7 9.1 11.2 0.87 10.1 8.7 1.8 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PDZ PF00595.24 RUS76564.1 - 4.6e-12 46.1 0.0 7.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS76564.1 - 1.9e-06 27.6 0.1 3.5e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS76564.1 - 0.0022 18.3 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TRIC PF05197.13 RUS76565.1 - 1.7 8.2 13.5 4.4 6.8 0.9 3.0 2 1 1 3 3 3 0 TRIC channel DUF4749 PF15936.5 RUS76568.1 - 5.1e-05 24.3 2.2 0.0019 19.3 0.3 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4749) DUF1842 PF08896.10 RUS76569.1 - 3.6e-11 43.3 39.8 0.59 10.4 0.3 9.1 1 1 9 10 10 10 10 Domain of unknown function (DUF1842) A_thal_3526 PF09713.10 RUS76569.1 - 1.8e-07 31.3 11.0 9.6 6.5 0.0 6.9 1 1 9 10 10 10 5 Plant protein 1589 of unknown function (A_thal_3526) B_solenoid_ydck PF18836.1 RUS76569.1 - 0.01 15.7 14.7 56 3.8 0.0 7.5 10 0 0 10 10 10 0 Beta solenoid repeat from YDCK DUF4197 PF13852.6 RUS76569.1 - 0.077 12.7 1.6 8.7 6.0 0.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4197) Glucodextran_C PF09985.9 RUS76569.1 - 0.12 11.8 0.4 1e+02 2.2 0.0 3.4 1 1 5 6 6 6 0 C-terminal binding-module, SLH-like, of glucodextranase Capsid-VNN PF11729.8 RUS76569.1 - 0.85 8.6 15.1 4.7 6.1 1.2 3.0 1 1 3 4 4 4 0 nodavirus capsid protein SufE PF02657.15 RUS76569.1 - 1.4 8.8 3.7 73 3.2 0.4 2.8 1 1 2 3 3 3 0 Fe-S metabolism associated domain DUF760 PF05542.11 RUS76569.1 - 1.9 8.9 7.8 3.6e+03 -1.6 7.8 4.8 1 1 0 1 1 1 0 Protein of unknown function (DUF760) PAH PF02671.21 RUS76571.1 - 1.6e-07 31.3 0.7 7.6e-07 29.2 0.3 2.3 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF1722 PF08349.11 RUS76571.1 - 0.03 14.6 0.4 6.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) OrfB_Zn_ribbon PF07282.11 RUS76571.1 - 4.7 7.2 7.4 4 7.4 2.8 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain F5_F8_type_C PF00754.25 RUS76572.1 - 1.7e-05 24.9 0.0 1.9e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 RUS76572.1 - 0.029 14.4 0.1 0.1 12.6 0.1 1.8 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal ANAPC10 PF03256.16 RUS76572.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) IMS PF00817.20 RUS76576.1 - 5e-42 143.4 0.0 5.7e-41 140.0 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 RUS76576.1 - 2.1e-22 80.0 1.0 5e-22 78.8 1.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 RUS76576.1 - 0.0013 18.9 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif SKA1 PF07160.12 RUS76577.1 - 1.7e-47 162.3 4.1 2e-47 162.1 4.1 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF3161 PF11362.8 RUS76577.1 - 0.0044 17.0 0.5 0.01 15.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) KIAA1430 PF13879.6 RUS76577.1 - 0.59 10.9 6.7 0.12 13.2 1.3 2.2 2 1 0 2 2 2 0 KIAA1430 homologue Spc7 PF08317.11 RUS76577.1 - 4 6.2 11.2 0.21 10.4 5.9 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein TIR_2 PF13676.6 RUS76578.1 - 1.1e-45 155.0 0.0 1.2e-21 77.5 0.0 3.7 3 0 0 3 3 3 2 TIR domain Death PF00531.22 RUS76578.1 - 6e-11 42.3 1.0 6e-11 42.3 1.0 3.8 3 1 1 4 4 4 1 Death domain TIR PF01582.20 RUS76578.1 - 3.6e-08 33.4 0.0 0.0033 17.3 0.0 2.8 2 0 0 2 2 2 2 TIR domain Aida_N PF08910.10 RUS76578.1 - 0.011 16.1 0.0 0.082 13.3 0.0 2.6 1 0 0 1 1 1 0 Aida N-terminus DUF1664 PF07889.12 RUS76578.1 - 0.022 14.8 6.2 0.14 12.2 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 RUS76578.1 - 0.023 13.9 2.3 0.066 12.4 2.3 1.7 1 0 0 1 1 1 0 Invariant surface glycoprotein Laminin_II PF06009.12 RUS76578.1 - 0.074 13.1 3.4 0.24 11.4 1.9 2.6 2 0 0 2 2 2 0 Laminin Domain II DUF5069 PF16798.5 RUS76578.1 - 0.38 11.0 3.3 9 6.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) RFC1 PF08519.12 RUS76578.1 - 0.64 10.2 4.1 1.4 9.1 0.1 3.4 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain DUF948 PF06103.11 RUS76578.1 - 9.1 6.6 7.5 14 6.0 3.4 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NIBRIN_BRCT_II PF16508.5 RUS76579.1 - 1.9e-17 63.7 0.0 8e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein Nbs1_C PF08599.10 RUS76579.1 - 3.5e-15 55.9 2.0 7.2e-15 54.9 2.0 1.6 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 FHA PF00498.26 RUS76579.1 - 2.1e-13 50.4 0.0 4.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 RUS76579.1 - 5.6e-06 26.6 0.1 0.00029 21.2 0.0 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 RUS76579.1 - 1.2e-05 25.1 0.0 7.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 RUS76579.1 - 5.1e-05 23.5 0.0 0.00031 21.0 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pilin_PilX PF11530.8 RUS76580.1 - 0.074 13.0 10.3 23 4.9 0.6 4.0 1 1 3 4 4 4 0 Minor type IV pilin, PilX HATPase_c PF02518.26 RUS76580.1 - 0.77 10.3 14.5 8.2e+02 0.5 14.5 3.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nudix_hydro PF18290.1 RUS76580.1 - 0.89 9.6 14.7 6.9 6.7 1.2 3.8 1 1 4 5 5 5 0 Nudix hydrolase domain Exo_endo_phos PF03372.23 RUS76581.1 - 8.2e-08 32.0 0.0 2.8e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aconitase_2_N PF06434.13 RUS76581.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus ABC_membrane PF00664.23 RUS76582.1 - 1.2e-64 218.6 32.1 1.6e-39 136.2 9.5 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS76582.1 - 4.8e-40 137.3 0.0 1.3e-27 97.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS76582.1 - 2.5e-09 36.9 0.5 0.00086 18.8 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS76582.1 - 5.2e-06 26.5 2.0 0.074 13.1 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS76582.1 - 2.6e-05 24.7 2.7 0.15 12.4 0.1 2.7 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RUS76582.1 - 5.7e-05 23.1 0.2 0.028 14.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RUS76582.1 - 7e-05 22.5 0.6 0.32 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RUS76582.1 - 0.00063 20.0 0.0 1.9 8.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 RUS76582.1 - 0.0016 17.5 0.1 0.048 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 RUS76582.1 - 0.0063 16.6 6.4 0.21 11.6 0.3 2.8 3 0 0 3 3 3 2 Helicase HerA, central domain Dynamin_N PF00350.23 RUS76582.1 - 0.01 15.9 3.9 0.045 13.8 0.6 2.5 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 RUS76582.1 - 0.016 14.5 0.9 0.98 8.7 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin TrwB_AAD_bind PF10412.9 RUS76582.1 - 0.036 13.0 0.8 2.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 RUS76582.1 - 0.036 13.9 0.8 7 6.4 0.1 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RUS76582.1 - 0.039 13.5 0.0 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RUS76582.1 - 0.078 12.5 0.5 3.7 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 RUS76582.1 - 0.15 11.7 2.6 16 5.2 0.7 3.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 RUS76582.1 - 0.18 11.0 0.3 9 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 RUS76582.1 - 0.22 12.1 0.2 29 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RUS76582.1 - 0.45 11.0 2.1 13 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain MTABC_N PF16185.5 RUS76582.1 - 2.2 7.7 11.4 0.037 13.5 3.2 2.2 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region ATP_bind_1 PF03029.17 RUS76582.1 - 3.2 7.4 4.5 10 5.8 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF1081 PF06448.11 RUS76583.1 - 6.2e-06 26.6 53.7 0.52 10.7 6.1 6.2 1 1 6 7 7 7 7 Domain of Unknown Function (DUF1081) Pcc1 PF09341.10 RUS76583.1 - 0.00014 21.9 5.3 12 6.1 2.3 5.5 1 1 1 2 2 2 2 Transcription factor Pcc1 Porin_3 PF01459.22 RUS76583.1 - 0.00083 18.9 21.3 4.8 6.5 0.3 6.7 1 1 6 7 7 7 5 Eukaryotic porin rve_2 PF13333.6 RUS76583.1 - 0.26 11.5 34.8 1.5e+02 2.7 0.2 14.8 2 1 14 16 16 16 0 Integrase core domain zf-H2C2_2 PF13465.6 RUS76584.1 - 7e-25 86.3 47.0 1.6e-07 31.5 0.9 8.4 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76584.1 - 1.9e-16 59.5 70.8 0.0021 18.4 1.7 9.8 9 0 0 9 9 9 8 Zinc finger, C2H2 type BTB PF00651.31 RUS76584.1 - 5.6e-16 58.8 0.0 1.6e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 RUS76584.1 - 2.8e-09 37.0 69.4 0.0025 18.5 1.5 10.0 10 0 0 10 10 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS76584.1 - 2e-07 30.6 65.2 8e-07 28.7 1.7 8.8 9 0 0 9 9 9 4 C2H2-type zinc-finger domain GAGA PF09237.11 RUS76584.1 - 7.9e-05 22.4 1.6 0.041 13.7 0.1 2.8 2 0 0 2 2 2 2 GAGA factor zf_C2H2_ZHX PF18387.1 RUS76584.1 - 0.00012 21.6 0.2 0.00012 21.6 0.2 7.1 2 1 4 7 7 7 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 RUS76584.1 - 0.029 14.7 42.9 2.4 8.6 5.1 7.0 2 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RUS76584.1 - 0.072 13.4 0.4 0.072 13.4 0.4 6.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 RUS76584.1 - 0.2 12.0 0.2 0.2 12.0 0.2 4.4 3 1 2 5 5 5 0 zinc-finger-containing domain FoP_duplication PF13865.6 RUS76584.1 - 0.55 10.8 3.9 1.4 9.5 3.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf_UBZ PF18439.1 RUS76584.1 - 0.87 9.2 13.7 5 6.8 0.1 5.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Vps36-NZF-N PF16988.5 RUS76584.1 - 2.2 7.7 9.7 1.9 7.9 0.2 3.9 4 1 1 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PND PF17949.1 RUS76585.1 - 1.2e-31 109.5 0.0 1.7e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 FANCM pseudonuclease domain HHH_2 PF12826.7 RUS76585.1 - 4.7e-07 29.8 0.0 9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 RUS76585.1 - 8.8e-05 23.0 0.0 0.00014 22.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 RUS76585.1 - 0.065 13.1 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Rad10 PF03834.14 RUS76585.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Dus PF01207.17 RUS76586.1 - 9.9e-32 110.3 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 RUS76586.1 - 0.00092 19.9 0.0 0.002 18.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif His_biosynth PF00977.21 RUS76586.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF5578 PF17741.1 RUS76587.1 - 1.2e-131 438.0 3.1 1.7e-131 437.5 3.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 RUS76587.1 - 6.6e-06 25.8 0.3 6.6e-06 25.8 0.3 1.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain HEAT_2 PF13646.6 RUS76587.1 - 0.00014 22.2 3.8 0.0018 18.6 0.0 3.7 3 1 1 4 4 4 1 HEAT repeats Arm PF00514.23 RUS76587.1 - 0.00024 21.0 0.3 0.59 10.3 0.1 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 RUS76587.1 - 0.0015 17.2 0.7 0.0015 17.2 0.7 1.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3361 PF11841.8 RUS76587.1 - 0.015 15.2 0.1 0.13 12.2 0.1 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) SCAB-Ig PF16709.5 RUS76589.1 - 0.02 14.9 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein DAGK_cat PF00781.24 RUS76589.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NUP50 PF08911.11 RUS76591.1 - 1.6e-17 63.9 0.1 1.6e-17 63.9 0.1 4.1 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 RUS76591.1 - 1.2e-08 35.3 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain LrgB PF04172.16 RUS76591.1 - 2.2 7.8 3.9 4 6.9 3.9 1.4 1 0 0 1 1 1 0 LrgB-like family RCC1 PF00415.18 RUS76593.1 - 2.1e-64 213.9 28.2 1.2e-12 48.2 4.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS76593.1 - 4.9e-32 109.0 47.3 4.8e-09 35.8 1.2 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat zf-RVT PF13966.6 RUS76594.1 - 1.6e-06 28.8 2.2 2.5e-05 24.9 0.8 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase CBFB_NFYA PF02045.15 RUS76595.1 - 2.6e-12 47.2 0.5 1e-11 45.3 0.5 2.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DDE_1 PF03184.19 RUS76597.1 - 2.4e-24 85.9 0.1 1.1e-23 83.8 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.16 RUS76597.1 - 0.0068 16.1 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Gln-synt_C PF00120.24 RUS76598.1 - 7.8e-60 202.7 0.0 1.4e-59 201.8 0.0 1.4 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain RVT_1 PF00078.27 RUS76599.1 - 2.3e-06 27.3 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleos_tra2_C PF07662.13 RUS76600.1 - 1.3e-25 90.5 0.4 1.5e-25 90.3 0.4 1.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus START PF01852.19 RUS76601.1 - 1.1e-24 87.1 0.3 1.7e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 START domain PH PF00169.29 RUS76601.1 - 7.8e-13 48.9 0.1 1.9e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 RUS76601.1 - 2.2e-08 34.3 0.1 5.2e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 RUS76601.1 - 2.3e-06 28.0 1.4 0.00036 20.9 0.7 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain Acyl_CoA_thio PF02551.15 RUS76601.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase PRP1_N PF06424.12 RUS76601.1 - 0.1 13.0 0.4 0.26 11.7 0.4 1.7 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CodY PF06018.14 RUS76601.1 - 0.14 11.7 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 CodY GAF-like domain BRCT_3 PF18428.1 RUS76602.1 - 4.3e-28 97.3 1.8 1.5e-25 89.2 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 RUS76602.1 - 1.5e-08 34.9 1.0 7.1e-07 29.5 0.0 3.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain 53-BP1_Tudor PF09038.10 RUS76602.1 - 1.7e-08 34.5 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT_2 PF16589.5 RUS76602.1 - 2.3e-08 34.3 0.1 4.8e-06 26.9 0.0 3.5 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain DUF4537 PF15057.6 RUS76602.1 - 7e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) RTT107_BRCT_5 PF16770.5 RUS76602.1 - 1.2e-05 25.1 0.5 7.2e-05 22.6 0.0 2.5 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_2 PF18104.1 RUS76602.1 - 3e-05 23.6 0.0 7.9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain DUF2781 PF10914.8 RUS76603.1 - 2.1e-07 31.4 10.8 2.1e-07 31.4 10.8 2.9 2 2 0 2 2 2 2 Protein of unknown function (DUF2781) DUF1180 PF06679.12 RUS76604.1 - 5.1e-24 85.6 0.0 5.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DHHC PF01529.20 RUS76605.1 - 2.7e-34 118.2 12.3 2.7e-34 118.2 12.3 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase LapA_dom PF06305.11 RUS76605.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Voltage_CLC PF00654.20 RUS76605.1 - 0.64 9.2 7.6 5.2 6.2 2.0 2.2 2 0 0 2 2 2 0 Voltage gated chloride channel Rcd1 PF04078.13 RUS76606.1 - 7.6e-131 435.1 2.1 8.6e-131 434.9 2.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Trans_reg_C PF00486.28 RUS76607.1 - 0.042 13.9 0.2 3 8.0 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal ATG11 PF10377.9 RUS76607.1 - 0.095 12.8 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 zf-C3HC4_3 PF13920.6 RUS76608.1 - 5.8e-06 26.1 17.5 9.6e-06 25.4 17.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS76608.1 - 1.3e-05 25.4 21.1 2.7e-05 24.4 21.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS76608.1 - 0.0017 18.2 20.8 0.0034 17.2 20.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS76608.1 - 0.0019 18.0 16.5 0.0042 16.9 16.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RUS76608.1 - 0.0026 17.6 21.6 0.0059 16.5 21.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS76608.1 - 0.0084 16.1 17.7 0.019 14.9 17.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RUS76608.1 - 0.0097 15.9 8.6 0.019 15.0 8.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RUS76608.1 - 0.042 14.1 17.2 0.086 13.1 16.7 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RUS76608.1 - 3.3 7.9 19.5 4.3 7.6 17.4 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS76608.1 - 5.3 7.2 15.0 14 5.8 15.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger tRNA-synt_1e PF01406.19 RUS76609.1 - 2.1e-121 404.9 0.6 3.3e-121 404.3 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RUS76609.1 - 8.5e-06 24.7 4.1 0.00016 20.6 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RUS76609.1 - 0.00046 18.6 1.8 0.001 17.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 RUS76609.1 - 0.014 14.3 2.1 0.029 13.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain His_Phos_1 PF00300.22 RUS76610.1 - 4.7e-17 62.3 0.0 8.3e-12 45.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) ATP-synt_S1 PF05827.12 RUS76611.1 - 0.0058 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) His_Phos_1 PF00300.22 RUS76612.1 - 0.0013 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MAF_flag10 PF01973.18 RUS76612.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 His_Phos_1 PF00300.22 RUS76613.1 - 4.6e-24 85.2 0.1 5e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LIM PF00412.22 RUS76615.1 - 1.6e-13 50.7 6.0 1.8e-13 50.5 5.3 1.5 2 0 0 2 2 2 1 LIM domain Y_phosphatase PF00102.27 RUS76616.1 - 3.2e-52 177.5 4.2 2.3e-48 164.8 0.6 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RUS76618.1 - 2.2e-09 37.5 0.2 1.2e-05 25.5 0.0 3.5 3 0 0 3 3 3 2 Fibronectin type III domain 7tm_2 PF00002.24 RUS76618.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) fn3 PF00041.21 RUS76619.1 - 2.6e-05 24.5 2.7 0.018 15.4 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain DUF4667 PF15700.5 RUS76619.1 - 2.4 8.2 12.2 2.8 8.0 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF3446 PF11928.8 RUS76619.1 - 3.1 8.2 21.3 5 7.5 21.3 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain SSP160 PF06933.11 RUS76619.1 - 3.5 5.7 9.6 3.3 5.8 9.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 RUS76619.1 - 7.8 6.0 29.2 9.5 5.8 29.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein fn3 PF00041.21 RUS76620.1 - 0.00018 21.8 0.1 0.0011 19.3 0.0 2.2 2 1 0 2 2 2 1 Fibronectin type III domain dsrm PF00035.26 RUS76621.1 - 1.4e-08 35.3 3.4 0.00076 20.1 0.1 4.0 4 1 1 5 5 5 2 Double-stranded RNA binding motif EI24 PF07264.11 RUS76621.1 - 0.092 13.0 10.1 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Peptidase_C13 PF01650.18 RUS76623.1 - 1.2e-22 80.7 0.6 1.7e-22 80.2 0.6 1.2 1 0 0 1 1 1 1 Peptidase C13 family NDK PF00334.19 RUS76624.1 - 4.6e-36 123.8 0.0 5.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4281 PF14108.6 RUS76624.1 - 0.02 15.3 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Ion_trans PF00520.31 RUS76625.1 - 7.3e-40 136.7 19.7 1e-39 136.2 19.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS76625.1 - 6.5e-11 42.0 7.5 6.5e-11 42.0 7.5 2.3 3 0 0 3 3 3 1 Ion channel BTB_2 PF02214.22 RUS76625.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain DUF5090 PF17009.5 RUS76625.1 - 0.22 11.5 13.0 0.46 10.4 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Peptidase_A24 PF01478.18 RUS76625.1 - 1.5 9.2 7.8 4 7.9 7.8 1.8 1 1 0 1 1 1 0 Type IV leader peptidase family Sushi PF00084.20 RUS76626.1 - 0.0015 19.1 0.9 0.0057 17.2 0.2 2.2 2 1 0 2 2 2 1 Sushi repeat (SCR repeat) Homeodomain PF00046.29 RUS76627.1 - 2.2e-20 72.3 1.6 3.6e-20 71.6 1.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS76627.1 - 0.0062 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 RUS76627.1 - 0.084 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Zip PF02535.22 RUS76629.1 - 1.1e-51 176.1 18.5 1.3e-31 110.1 12.7 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Urocanase PF01175.18 RUS76629.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain FA_desaturase PF00487.24 RUS76629.1 - 0.33 10.8 2.9 0.19 11.5 0.6 1.8 2 0 0 2 2 2 0 Fatty acid desaturase Peptidase_C1 PF00112.23 RUS76630.1 - 1.8e-63 214.6 6.5 2.1e-63 214.3 6.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RUS76630.1 - 2e-11 43.6 0.0 3.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS76630.1 - 0.027 13.3 5.0 0.089 11.5 0.4 2.5 3 0 0 3 3 3 0 Peptidase C1-like family DUF1451 PF07295.11 RUS76630.1 - 6 6.9 7.3 4.5 7.3 5.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain Sugar_tr PF00083.24 RUS76631.1 - 6.1e-24 84.7 14.8 2.5e-14 53.0 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS76631.1 - 9.1e-22 77.5 20.8 1.5e-21 76.7 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 RUS76631.1 - 0.00017 20.3 16.2 0.0016 17.0 1.9 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 RUS76631.1 - 0.00059 18.4 0.3 0.0014 17.2 0.3 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DC_STAMP PF07782.13 RUS76631.1 - 0.077 12.8 1.6 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 DC-STAMP-like protein Sugar_tr PF00083.24 RUS76632.1 - 3.5e-23 82.2 6.1 2.6e-15 56.2 0.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS76632.1 - 1.1e-19 70.5 11.1 1.9e-19 69.8 11.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 RUS76632.1 - 0.0013 17.3 3.2 0.0013 17.3 3.2 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 RUS76632.1 - 0.0045 15.5 2.5 0.0069 14.9 1.8 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 RUS76633.1 - 8.2e-18 64.5 0.1 9.9e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS76633.1 - 5.9e-15 55.0 1.4 8.8e-15 54.5 1.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RUS76633.1 - 1.5e-05 23.6 0.6 2.2e-05 23.1 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 RUS76633.1 - 0.0035 16.0 3.2 0.0062 15.2 3.2 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Frag1 PF10277.9 RUS76634.1 - 1.9e-32 112.6 19.2 2.2e-32 112.4 19.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF996 PF06195.13 RUS76634.1 - 0.21 11.9 3.6 0.43 10.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Alpha-amylase PF00128.24 RUS76635.1 - 5.5e-12 45.9 0.0 1.6e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 RUS76635.1 - 0.00019 21.8 0.4 0.0013 19.2 0.1 2.6 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain CD34_antigen PF06365.12 RUS76636.1 - 0.00051 19.7 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 CD34/Podocalyxin family baeRF_family8 PF18851.1 RUS76636.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 zf-TAZ PF02135.16 RUS76637.1 - 1.5e-07 31.7 14.2 0.0019 18.6 4.6 3.0 1 1 2 3 3 3 3 TAZ zinc finger Cys_Knot_tox PF17486.2 RUS76637.1 - 3.3e-06 27.2 17.8 0.2 11.9 0.7 4.1 1 1 4 5 5 5 5 Cystine knot toxins DUF4247 PF14042.6 RUS76637.1 - 0.0091 16.7 5.9 2 9.1 1.2 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4247) Crisp PF08562.10 RUS76637.1 - 0.14 12.8 29.4 21 5.8 0.8 4.9 1 1 3 4 4 4 0 Crisp Arteri_GP4 PF02497.15 RUS76637.1 - 0.18 12.0 13.3 9.1 6.4 0.4 4.0 1 1 3 4 4 4 0 Arterivirus glycoprotein zinc-ribbons_6 PF07191.12 RUS76637.1 - 1.6 8.8 8.9 49 4.0 6.0 3.1 1 1 1 2 2 2 0 zinc-ribbons GARP PF16731.5 RUS76637.1 - 2.6 7.7 12.0 2.6 7.7 1.0 2.9 1 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma F_actin_bind PF08919.10 RUS76637.1 - 5.6 7.1 8.8 16 5.7 0.6 3.2 1 1 1 2 2 2 0 F-actin binding Cadherin PF00028.17 RUS76638.1 - 4.5e-70 232.2 0.3 1.7e-22 79.7 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Laminin_G_2 PF02210.24 RUS76638.1 - 1.2e-23 84.0 0.0 2.6e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 RUS76638.1 - 1.4e-23 82.8 74.5 3.2e-07 30.5 8.7 6.2 5 0 0 5 5 5 5 EGF-like domain Laminin_G_1 PF00054.23 RUS76638.1 - 6.6e-17 61.9 0.0 1.2e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 RUS76638.1 - 2.6e-09 37.3 61.2 0.0003 21.3 6.0 7.1 6 0 0 6 6 6 5 Human growth factor-like EGF Cadherin_3 PF16184.5 RUS76638.1 - 3.3e-09 36.7 2.1 0.00086 19.3 0.1 4.2 4 0 0 4 4 4 3 Cadherin-like Cadherin_4 PF17803.1 RUS76638.1 - 5.9e-05 23.6 8.7 0.71 10.5 0.5 4.5 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 RUS76638.1 - 0.0021 17.9 0.1 0.99 9.3 0.0 3.2 3 0 0 3 3 3 1 Cadherin-like DUF4381 PF14316.6 RUS76638.1 - 0.015 15.5 0.2 0.028 14.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Band_7 PF01145.25 RUS76638.1 - 0.062 13.3 0.9 13 5.8 0.2 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family BatD PF13584.6 RUS76638.1 - 0.11 11.3 0.1 0.3 9.8 0.0 1.7 2 0 0 2 2 2 0 Oxygen tolerance RCR PF12273.8 RUS76638.1 - 0.13 12.9 1.9 0.22 12.2 0.1 2.5 2 0 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 RUS76638.1 - 0.16 12.9 0.0 0.46 11.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_2_4 PF16082.5 RUS76638.1 - 0.19 11.4 0.2 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LST1 PF05083.13 RUS76638.1 - 0.21 11.9 1.2 6.7 7.1 0.5 2.7 2 0 0 2 2 2 0 LST-1 protein TRP PF06011.12 RUS76638.1 - 0.25 10.0 0.1 0.37 9.5 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel bZIP_2 PF07716.15 RUS76639.1 - 0.017 15.2 4.4 0.037 14.1 4.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 RUS76639.1 - 0.052 14.1 2.5 0.12 12.9 2.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 RUS76639.1 - 0.64 10.2 5.9 1.7 8.8 5.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF3977 PF13122.6 RUS76640.1 - 1.5e-05 25.1 5.7 20 5.5 0.0 5.7 1 1 5 6 6 6 5 Protein of unknown function (DUF3977) PCI PF01399.27 RUS76640.1 - 0.006 17.1 1.7 3.8 8.1 0.3 3.2 1 1 2 3 3 3 3 PCI domain Phage_spike PF18715.1 RUS76640.1 - 1.4 9.0 9.6 89 3.3 0.1 5.1 5 0 0 5 5 5 0 Phage spike trimer T-box PF00907.22 RUS76641.1 - 6.3e-76 254.7 0.0 1.1e-75 254.0 0.0 1.4 1 0 0 1 1 1 1 T-box Androgen_recep PF02166.16 RUS76641.1 - 0.76 8.6 6.7 1.3 7.8 6.7 1.3 1 0 0 1 1 1 0 Androgen receptor Molydop_binding PF01568.21 RUS76642.1 - 0.025 14.6 0.0 7.4 6.6 0.0 3.3 1 1 2 3 3 3 0 Molydopterin dinucleotide binding domain Flu_NS2 PF00601.19 RUS76642.1 - 0.14 12.4 2.1 33 4.9 0.2 3.6 1 1 1 3 3 3 0 Influenza non-structural protein (NS2) Ycf4 PF02392.16 RUS76643.1 - 0.45 10.0 3.9 5.5 6.5 2.3 2.2 1 1 1 2 2 2 0 Ycf4 Rtt106 PF08512.12 RUS76643.1 - 1.6 9.2 13.4 2.4e+03 -1.0 13.4 3.5 1 1 0 1 1 1 0 Histone chaperone Rttp106-like PAS PF00989.25 RUS76645.1 - 9.4e-08 32.0 0.0 2.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RUS76645.1 - 1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 RUS76645.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_2 PF08446.11 RUS76645.1 - 0.021 15.5 0.0 0.051 14.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 RUS76645.1 - 0.036 14.3 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.6 RUS76646.1 - 3.2e-19 69.1 0.3 4.5e-19 68.7 0.3 1.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 RUS76646.1 - 2.6e-07 30.8 0.0 3.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold DUF4927 PF16279.5 RUS76647.1 - 0.069 14.2 4.1 1.7 9.7 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4927) FoP_duplication PF13865.6 RUS76647.1 - 0.72 10.4 5.7 0.3 11.7 2.1 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 TFIIA PF03153.13 RUS76649.1 - 0.54 10.2 10.6 0.5 10.3 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 RUS76650.1 - 0.0032 17.5 16.1 0.0041 17.2 16.1 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 RUS76650.1 - 0.051 12.4 19.7 0.012 14.5 12.9 2.5 2 0 0 2 2 2 0 Androgen receptor Neur_chan_memb PF02932.16 RUS76650.1 - 0.067 13.2 1.4 0.081 13.0 1.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC106 PF15794.5 RUS76650.1 - 0.092 12.4 9.7 0.16 11.7 9.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TERB2 PF15101.6 RUS76650.1 - 0.1 12.6 7.4 0.2 11.7 7.4 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SprA-related PF12118.8 RUS76650.1 - 0.12 11.5 12.7 0.17 11.0 12.7 1.2 1 0 0 1 1 1 0 SprA-related family Vps39_2 PF10367.9 RUS76650.1 - 0.16 12.4 4.2 0.35 11.3 4.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Ndc1_Nup PF09531.10 RUS76650.1 - 0.26 9.9 7.4 0.29 9.8 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM51 PF15345.6 RUS76650.1 - 0.27 11.1 6.6 0.43 10.4 6.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EIIBC-GUT_N PF03612.14 RUS76650.1 - 0.3 10.8 3.4 0.48 10.1 3.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 RUS76650.1 - 0.56 8.9 6.5 0.71 8.6 6.5 1.1 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 RUS76650.1 - 1.4 8.7 3.8 2.1 8.1 3.8 1.2 1 0 0 1 1 1 0 VIT family DUF3464 PF11947.8 RUS76650.1 - 3.5 7.4 8.7 6.9 6.4 8.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SNF PF00209.18 RUS76651.1 - 8.1e-206 684.7 36.1 6e-204 678.6 36.1 2.0 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family RNA_pol_3_Rpc31 PF11705.8 RUS76652.1 - 0.035 14.4 24.6 0.056 13.7 24.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 RUS76652.1 - 0.042 12.1 10.0 0.059 11.7 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 RUS76652.1 - 0.1 12.2 13.4 0.16 11.6 13.4 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS76652.1 - 0.32 10.3 28.9 0.059 12.7 25.3 1.7 2 0 0 2 2 2 0 NOA36 protein TFIIA PF03153.13 RUS76652.1 - 0.66 9.9 20.7 0.79 9.7 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RUS76652.1 - 1.4 7.1 22.8 1.8 6.7 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS76652.1 - 1.9 7.7 15.3 2.6 7.3 15.3 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 RUS76652.1 - 3.2 6.8 35.8 5.8 5.9 35.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS76652.1 - 5.5 5.0 32.0 8.6 4.3 32.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4816 PF16086.5 RUS76653.1 - 7.1e-07 29.0 11.1 1.1 9.3 11.1 4.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4816) EMI PF07546.13 RUS76653.1 - 0.00075 20.2 33.1 1.8e+04 -9.1 33.1 4.6 1 1 0 1 1 0 0 EMI domain Ribosomal_S20p PF01649.18 RUS76653.1 - 0.018 15.7 8.8 1.5 9.6 6.0 2.4 1 1 1 2 2 2 0 Ribosomal protein S20 TetR_C_8 PF14278.6 RUS76653.1 - 0.03 14.4 7.0 0.27 11.3 1.9 2.3 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region YTV PF07639.11 RUS76653.1 - 0.25 11.4 31.9 1.8e+04 -5.7 31.9 4.1 1 1 0 1 1 0 0 YTV TetR_C_19 PF17924.1 RUS76653.1 - 0.33 11.6 2.2 2.5 8.7 2.2 2.1 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GED PF02212.18 RUS76653.1 - 0.6 10.3 6.9 2.7 8.2 1.8 2.2 1 1 1 2 2 2 0 Dynamin GTPase effector domain Mito_carr PF00153.27 RUS76653.1 - 0.77 9.7 5.7 1.3 9.0 4.7 2.0 1 1 1 2 2 2 0 Mitochondrial carrier protein Sld7_C PF18596.1 RUS76653.1 - 1.1 9.5 28.1 1.4e+03 -0.5 9.5 6.0 1 1 1 2 2 2 0 Sld7 C-terminal domain PhoLip_ATPase_C PF16212.5 RUS76653.1 - 1.9 8.2 15.4 4.6 6.9 4.7 2.1 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal CelTOS PF18659.1 RUS76653.1 - 8.8 6.8 14.1 1e+03 0.2 13.9 2.6 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Cadherin PF00028.17 RUS76654.1 - 6.5e-89 292.6 8.9 1.2e-15 57.7 0.0 7.6 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS76654.1 - 2.8e-10 39.9 0.0 8.8e-06 25.5 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like He_PIG PF05345.12 RUS76654.1 - 0.28 11.4 13.6 47 4.3 0.1 7.1 6 2 1 7 7 7 0 Putative Ig domain FctA PF12892.7 RUS76654.1 - 0.62 10.9 7.2 1.7 9.5 0.3 4.0 3 1 0 3 3 3 0 Spy0128-like isopeptide containing domain Shisa PF13908.6 RUS76654.1 - 0.82 9.9 3.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator p450 PF00067.22 RUS76655.1 - 8.7e-110 367.6 0.0 1.1e-109 367.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS76656.1 - 6.2e-51 173.6 0.0 7.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNase_PH PF01138.21 RUS76657.1 - 1.5e-27 96.7 0.0 5.6e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS76657.1 - 7.4e-09 35.5 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 T-box PF00907.22 RUS76659.1 - 8.6e-80 267.3 0.1 1e-79 267.1 0.1 1.1 1 0 0 1 1 1 1 T-box L_lactis_RepB_C PF06430.12 RUS76661.1 - 0.0013 18.8 1.2 7.8 6.5 0.1 3.3 2 1 1 3 3 3 3 Lactococcus lactis RepB C-terminus TRAPPC-Trs85 PF12739.7 RUS76661.1 - 0.22 10.5 1.6 8.7 5.2 0.2 2.2 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF3139 PF11337.8 RUS76662.1 - 0.13 12.9 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) T-box PF00907.22 RUS76663.1 - 2e-78 262.9 0.0 3.1e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 T-box VEFS-Box PF09733.9 RUS76663.1 - 0.14 12.0 1.4 0.33 10.7 1.4 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Vac7 PF12751.7 RUS76664.1 - 2.5 7.5 12.7 3.2 7.1 12.7 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 zf-CCHC PF00098.23 RUS76665.1 - 3.6e-07 30.0 5.1 5.5e-07 29.4 5.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS76665.1 - 0.00087 19.2 0.6 0.00087 19.2 0.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS76665.1 - 0.043 13.6 3.0 0.077 12.8 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Cdd1 PF11731.8 RUS76666.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus GTP_EFTU_D3 PF03143.17 RUS76668.1 - 0.05 13.9 0.2 38 4.6 0.0 2.9 1 1 3 4 4 4 0 Elongation factor Tu C-terminal domain Pep3_Vps18 PF05131.14 RUS76672.1 - 0.014 15.2 0.2 0.04 13.7 0.2 1.8 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family WSD PF15613.6 RUS76672.1 - 8.9 6.9 13.9 2.8 8.5 9.3 2.9 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif INT_SG_DDX_CT_C PF15300.6 RUS76673.1 - 2.5e-19 68.8 3.8 5.4e-19 67.7 3.8 1.5 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 RUS76673.1 - 1e-18 67.9 0.0 3.7e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RUS76673.1 - 1.8e-05 25.1 0.1 6.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain RPN6_N PF18055.1 RUS76673.1 - 0.0082 16.5 0.3 0.023 15.0 0.3 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain ApbE PF02424.15 RUS76673.1 - 0.053 13.0 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 ApbE family Tox-REase-2 PF15646.6 RUS76673.1 - 0.13 12.5 0.7 2.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 Sulfotransfer_1 PF00685.27 RUS76674.1 - 1.3e-24 87.1 0.5 1.6e-24 86.8 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS76674.1 - 1.1e-17 65.2 0.4 5.7e-13 49.8 0.4 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS76674.1 - 0.013 15.4 0.2 0.013 15.4 0.2 1.7 2 0 0 2 2 2 0 Sulfotransferase family 2OG-FeII_Oxy_2 PF13532.6 RUS76675.1 - 7.4e-11 42.6 0.0 4e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.28 RUS76676.1 - 6.5e-12 45.6 0.0 8.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RPN7 PF10602.9 RUS76677.1 - 1.4e-63 213.7 0.7 3.5e-63 212.4 0.2 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 RUS76677.1 - 3e-18 66.2 1.2 5.6e-18 65.4 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 RUS76677.1 - 0.0053 16.8 3.7 0.17 12.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS76677.1 - 0.045 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 RUS76677.1 - 0.083 12.7 1.4 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3715 PF12509.8 RUS76679.1 - 3.7e-23 82.2 0.1 1.5e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3715) DTW PF03942.15 RUS76681.1 - 2.7e-35 121.9 0.0 3.7e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 RUS76681.1 - 0.096 12.9 0.6 0.21 11.8 0.6 1.5 1 0 0 1 1 1 0 B-box zinc finger Noc2 PF03715.13 RUS76682.1 - 5.1e-118 393.7 11.5 1.4e-117 392.3 11.5 1.8 1 0 0 1 1 1 1 Noc2p family Telomere_reg-2 PF10193.9 RUS76682.1 - 0.61 10.6 3.3 0.9 10.0 0.6 2.6 3 0 0 3 3 3 0 Telomere length regulation protein Band_7 PF01145.25 RUS76683.1 - 8e-21 74.8 0.5 1.3e-20 74.1 0.1 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Catalase-rel PF06628.12 RUS76683.1 - 0.057 13.6 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Catalase-related immune-responsive TPP_enzyme_C PF02775.21 RUS76684.1 - 3.2e-24 85.5 1.1 6.8e-24 84.4 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 RUS76684.1 - 5.6e-17 61.9 0.0 1.1e-15 57.7 0.0 2.5 2 2 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TrkA_TMD PF18613.1 RUS76685.1 - 0.0061 16.0 0.4 0.013 14.9 0.4 1.5 1 0 0 1 1 1 1 Tyrosine kinase receptor A trans-membrane domain HSP33 PF01430.19 RUS76685.1 - 0.06 12.8 1.3 0.07 12.5 1.3 1.1 1 0 0 1 1 1 0 Hsp33 protein TnsD PF15978.5 RUS76685.1 - 0.062 12.3 1.7 0.079 11.9 1.7 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D C1_1 PF00130.22 RUS76685.1 - 0.44 10.5 6.0 1 9.3 0.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RPN1_RPN2_N PF17781.1 RUS76686.1 - 5.5e-124 413.6 1.3 1.1e-123 412.5 1.3 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 RUS76686.1 - 7.3e-24 83.0 33.3 2.6e-05 24.4 0.3 9.8 12 0 0 12 12 12 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RUS76686.1 - 6.9e-09 36.0 0.3 0.0034 17.7 0.1 4.1 3 1 0 3 3 3 2 HEAT repeats COPI_C PF06957.11 RUS76686.1 - 0.093 11.5 0.9 0.45 9.2 0.1 2.0 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus BatD PF13584.6 RUS76687.1 - 0.083 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance PI3_PI4_kinase PF00454.27 RUS76688.1 - 5.5e-40 137.8 0.0 1.2e-39 136.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RUS76688.1 - 6.9e-37 126.7 0.3 1.3e-36 125.7 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 RUS76688.1 - 1.5e-17 63.8 0.0 4.1e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain PI3K_C2 PF00792.24 RUS76688.1 - 2.7e-13 50.0 0.0 1.7e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PX PF00787.24 RUS76688.1 - 4.3e-12 46.0 1.2 8.9e-12 45.0 0.2 2.1 2 0 0 2 2 2 1 PX domain DUF4135 PF13575.6 RUS76688.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) HEAT_2 PF13646.6 RUS76688.1 - 0.15 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats FlaC_arch PF05377.11 RUS76688.1 - 3.5 8.1 4.3 6.4 7.3 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Homeodomain PF00046.29 RUS76689.1 - 6.4e-22 77.2 2.2 1.5e-21 76.0 2.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS76689.1 - 0.00045 20.1 0.0 0.00097 19.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain OMPdecase PF00215.24 RUS76691.1 - 3.3e-73 246.0 0.0 6.1e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 RUS76691.1 - 4.5e-12 45.8 0.0 9.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ALS2CR8 PF15299.6 RUS76692.1 - 8.9e-22 78.1 14.8 2.8e-10 40.5 9.2 2.4 2 0 0 2 2 2 2 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Pannexin_like PF12534.8 RUS76692.1 - 0.014 14.5 0.7 0.024 13.7 0.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 FAM176 PF14851.6 RUS76692.1 - 0.45 10.2 3.2 0.29 10.8 0.4 2.1 2 0 0 2 2 2 0 FAM176 family Pex14_N PF04695.13 RUS76692.1 - 0.92 10.2 6.4 2 9.0 6.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3687 PF12459.8 RUS76694.1 - 0.0072 15.8 0.6 0.8 9.3 0.1 2.4 2 0 0 2 2 2 2 D-Ala-teichoic acid biosynthesis protein DAGK_prokar PF01219.19 RUS76694.1 - 0.073 12.9 2.4 0.096 12.5 2.4 1.1 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase Ets PF00178.22 RUS76695.1 - 9.2e-30 102.9 3.3 1.7e-29 102.1 3.3 1.4 1 0 0 1 1 1 1 Ets-domain TMEM154 PF15102.6 RUS76695.1 - 0.00066 19.6 1.6 0.00066 19.6 1.6 2.7 3 0 0 3 3 3 1 TMEM154 protein family EphA2_TM PF14575.6 RUS76695.1 - 0.0048 17.8 0.2 0.013 16.4 0.1 1.8 2 0 0 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 RUS76695.1 - 0.0053 17.7 0.7 0.0053 17.7 0.7 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 RUS76695.1 - 0.0067 16.3 3.4 0.0067 16.3 3.4 2.1 2 0 0 2 2 1 1 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.6 RUS76695.1 - 0.01 16.1 5.7 0.025 14.9 5.7 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Tmemb_9 PF05434.11 RUS76695.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 TMEM9 DUF929 PF06053.11 RUS76695.1 - 0.026 13.8 5.0 0.045 13.0 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) IcmF-related PF06761.12 RUS76695.1 - 0.03 13.8 0.9 0.048 13.1 0.9 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Shisa PF13908.6 RUS76695.1 - 0.068 13.4 0.4 0.068 13.4 0.4 2.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 RUS76695.1 - 0.11 12.8 4.1 0.3 11.4 4.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 RUS76695.1 - 0.19 11.3 4.9 0.42 10.2 4.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family MPS-4 PF17523.2 RUS76695.1 - 0.35 11.0 2.7 0.76 9.9 2.7 1.5 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 ASFV_J13L PF05568.11 RUS76695.1 - 0.89 9.3 11.6 0.65 9.7 7.7 2.5 2 0 0 2 2 2 0 African swine fever virus J13L protein Synaptobrevin PF00957.21 RUS76695.1 - 3.3 7.6 11.3 9.1 6.2 11.3 1.8 1 0 0 1 1 1 0 Synaptobrevin LRRC37AB_C PF14914.6 RUS76695.1 - 6 6.8 6.9 14 5.6 6.9 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain SF3A2 PF16835.5 RUS76697.1 - 5.2e-38 129.3 0.9 8.7e-38 128.6 0.9 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 RUS76697.1 - 4.4e-07 30.1 2.0 4.4e-07 30.1 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 RUS76697.1 - 3e-06 27.2 1.0 4.9e-06 26.5 1.0 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 RUS76697.1 - 0.067 12.8 3.2 0.12 12.0 3.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like LPD24 PF18839.1 RUS76697.1 - 0.15 12.4 0.1 24 5.3 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 zf-C2H2_jaz PF12171.8 RUS76697.1 - 7.6 6.9 6.7 13 6.2 5.0 2.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2451 PF10474.9 RUS76698.1 - 3.1e-85 285.7 4.2 5.4e-85 284.9 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 RUS76698.1 - 1.8e-17 63.5 1.4 1.1e-16 61.0 0.1 2.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Vps54 PF07928.12 RUS76698.1 - 3 8.3 4.6 10 6.5 0.2 3.2 3 1 0 3 3 3 0 Vps54-like protein Vps54_N PF10475.9 RUS76699.1 - 2.2e-20 73.1 0.3 2.6e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex I-set PF07679.16 RUS76700.1 - 1.3e-46 156.6 0.1 3e-17 62.5 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS76700.1 - 1.4e-41 141.0 1.6 1.7e-14 54.2 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS76700.1 - 3.1e-30 104.2 0.1 2.3e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS76700.1 - 2.8e-23 82.0 1.6 7e-08 32.7 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS76700.1 - 9.2e-21 74.1 6.4 3e-07 30.6 0.0 5.4 4 2 0 4 4 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS76700.1 - 3.1e-11 42.6 0.0 4.6e-05 22.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 RUS76700.1 - 8.8e-07 29.2 0.5 0.17 12.3 0.0 4.2 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 RUS76700.1 - 0.00014 21.9 2.1 0.0029 17.6 0.1 3.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RUS76700.1 - 0.00036 20.8 0.4 0.64 10.4 0.0 3.9 4 0 0 4 4 3 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 RUS76700.1 - 0.0021 18.2 0.0 10 6.3 0.0 3.4 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 RUS76700.1 - 0.0024 17.8 0.9 0.21 11.5 0.0 3.4 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 RUS76700.1 - 0.0025 18.1 0.5 1.5 9.1 0.0 4.5 4 2 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 RUS76700.1 - 0.0068 16.6 0.3 4.2 7.6 0.0 4.1 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 RUS76700.1 - 0.01 15.8 0.9 27 4.9 0.1 3.9 3 1 1 4 4 4 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS76700.1 - 0.032 14.3 0.0 0.26 11.3 0.0 2.5 3 0 0 3 3 3 0 C17orf99 Ig domain BiPBP_C PF06832.12 RUS76700.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family VIR_N PF15912.5 RUS76700.1 - 0.11 12.1 2.6 0.23 11.0 1.4 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal SUIM_assoc PF16619.5 RUS76700.1 - 0.5 10.5 3.0 6.8 6.8 0.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GrpE PF01025.19 RUS76701.1 - 2.5e-43 147.6 1.3 3.3e-43 147.2 1.3 1.1 1 0 0 1 1 1 1 GrpE Syntaxin-18_N PF10496.9 RUS76701.1 - 0.011 15.9 0.2 0.022 15.0 0.2 1.4 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1204 PF06721.11 RUS76701.1 - 0.017 14.6 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) T4SS PF07996.11 RUS76701.1 - 0.021 15.2 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins Rho_Binding PF08912.11 RUS76701.1 - 0.027 15.3 2.1 0.052 14.4 2.1 1.5 1 0 0 1 1 1 0 Rho Binding DUF5320 PF17253.2 RUS76701.1 - 0.032 15.3 0.0 0.054 14.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) HALZ PF02183.18 RUS76701.1 - 0.13 12.5 2.8 0.25 11.6 2.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28 PF14772.6 RUS76701.1 - 0.13 12.3 3.6 0.16 12.1 2.4 1.7 2 0 0 2 2 2 0 Sperm tail FokI_C PF02980.16 RUS76701.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain Prefoldin PF02996.17 RUS76701.1 - 0.23 11.4 3.2 0.47 10.4 3.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit Alba PF01918.21 RUS76702.1 - 4.5e-14 52.0 1.2 7.5e-14 51.3 1.2 1.4 1 0 0 1 1 1 1 Alba MGAT2 PF05060.14 RUS76703.1 - 5.6e-141 469.6 7.2 6.6e-141 469.4 7.2 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Aldo_ket_red PF00248.21 RUS76704.1 - 1.5e-48 165.5 0.0 2.8e-48 164.6 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 RUS76704.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Integrase_H2C2 PF17921.1 RUS76705.1 - 1.7e-10 40.8 0.1 1.7e-10 40.8 0.1 2.2 3 0 0 3 3 3 1 Integrase zinc binding domain Lectin_C PF00059.21 RUS76705.1 - 2.7e-10 40.9 0.5 0.0011 19.7 0.2 2.8 2 0 0 2 2 2 2 Lectin C-type domain zf-H2C2 PF09337.10 RUS76705.1 - 0.001 19.3 0.2 0.0022 18.2 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger CrtC PF07143.11 RUS76707.1 - 0.0039 17.9 0.0 0.0088 16.7 0.0 1.5 1 1 1 2 2 2 1 CrtC N-terminal lipocalin domain Exo_endo_phos_2 PF14529.6 RUS76708.1 - 8.9e-19 67.5 1.0 2e-18 66.3 0.1 2.0 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS76708.1 - 3.7e-05 23.4 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family rve PF00665.26 RUS76710.1 - 1.4e-10 41.4 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RUS76710.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_ab PF00006.25 RUS76710.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pullulanase_Ins PF18494.1 RUS76710.1 - 0.16 12.4 8.0 2.7 8.5 0.8 2.6 1 1 1 2 2 2 0 Pullulanase Ins domain LMBR1 PF04791.16 RUS76711.1 - 3.7e-16 59.1 10.2 4.3e-16 58.9 10.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein GWT1 PF06423.12 RUS76711.1 - 0.0021 18.2 2.1 0.0036 17.5 2.1 1.5 1 1 0 1 1 1 1 GWT1 DUF973 PF06157.11 RUS76711.1 - 0.01 14.9 3.8 0.014 14.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Trep_Strep PF09605.10 RUS76711.1 - 0.011 15.7 12.5 0.016 15.2 12.5 1.3 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Bap31 PF05529.12 RUS76711.1 - 0.019 14.8 0.3 0.019 14.8 0.3 1.8 2 1 0 2 2 2 0 Bap31/Bap29 transmembrane region Cyt_bd_oxida_II PF02322.15 RUS76711.1 - 0.24 10.7 15.9 0.041 13.3 0.9 2.0 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II Claudin_2 PF13903.6 RUS76711.1 - 0.34 10.6 7.7 0.1 12.3 3.2 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ATP_synt_H PF05493.13 RUS76711.1 - 5 7.7 10.2 5.1 7.6 1.9 3.1 1 1 3 4 4 4 0 ATP synthase subunit H TPT PF03151.16 RUS76712.1 - 1.2e-65 221.7 17.5 1.4e-65 221.5 17.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS76712.1 - 7.7e-12 45.5 21.4 1.8e-06 28.1 7.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RUS76712.1 - 1.9e-07 30.6 20.3 3.2e-07 29.9 20.3 1.4 1 1 0 1 1 1 1 UAA transporter family LRR_6 PF13516.6 RUS76713.1 - 2e-33 111.6 14.7 0.00045 20.0 0.1 9.5 9 0 0 9 9 9 7 Leucine Rich repeat LRR_1 PF00560.33 RUS76713.1 - 3.7e-07 29.8 0.7 30 5.7 0.0 7.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 RUS76713.1 - 0.00013 22.2 14.5 0.0092 16.4 0.9 5.5 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS76713.1 - 0.00051 19.8 13.6 0.045 13.5 1.0 6.3 7 1 0 7 7 7 2 Leucine rich repeat CLP1_P PF16575.5 RUS76713.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Glyco_hydro_31 PF01055.26 RUS76714.1 - 3.3e-53 181.4 0.8 6.4e-53 180.5 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 RUS76714.1 - 3.8e-05 22.8 0.4 5.7e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 Melibiase ArsA_HSP20 PF17886.1 RUS76714.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Ephrin_rec_like PF07699.13 RUS76715.1 - 9.4e-05 22.1 3.3 9.4e-05 22.1 3.3 2.3 1 1 1 2 2 2 1 Putative ephrin-receptor like Yae1_N PF09811.9 RUS76715.1 - 0.059 13.1 0.4 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Integrase_H2C2 PF17921.1 RUS76716.1 - 6.4e-13 48.6 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS76716.1 - 2.6e-08 34.1 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 RUS76716.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS76716.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF1918 PF08940.11 RUS76716.1 - 0.34 10.5 1.5 0.42 10.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) PLAC8 PF04749.17 RUS76718.1 - 5e-13 49.9 3.8 9.6e-13 49.0 3.8 1.5 1 1 0 1 1 1 1 PLAC8 family ASC PF00858.24 RUS76719.1 - 3e-79 267.1 0.6 4.2e-79 266.6 0.4 1.3 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Nup54 PF13874.6 RUS76719.1 - 0.055 13.6 1.2 0.16 12.1 1.2 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Copper-bind PF00127.20 RUS76719.1 - 0.077 13.5 0.3 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family ASC PF00858.24 RUS76720.1 - 3.4e-16 59.2 0.0 5.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel RT_RNaseH_2 PF17919.1 RUS76720.1 - 1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CENP-B_dimeris PF09026.10 RUS76720.1 - 0.00024 21.4 7.7 0.00046 20.5 7.7 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain GCIP PF13324.6 RUS76720.1 - 0.065 12.8 1.5 0.096 12.3 1.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF3246 PF11596.8 RUS76720.1 - 0.082 12.3 3.5 0.12 11.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.6 RUS76720.1 - 0.14 12.6 11.2 0.26 11.7 11.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 RUS76720.1 - 0.32 11.0 5.9 0.8 9.7 5.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 RUS76720.1 - 0.35 10.7 2.7 0.5 10.2 2.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 RUS76720.1 - 0.38 9.0 4.5 0.49 8.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 RUS76720.1 - 0.43 10.8 8.5 0.76 10.0 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 RUS76720.1 - 0.69 9.6 3.8 0.22 11.2 0.9 1.6 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.12 RUS76720.1 - 0.81 9.4 13.2 1.2 8.9 13.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RUS76720.1 - 0.92 8.8 15.3 1.3 8.3 15.3 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS76720.1 - 0.98 7.4 8.3 1.4 7.0 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RUS76720.1 - 2.2 7.3 14.8 3 6.9 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2076 PF09849.9 RUS76720.1 - 9.4 6.2 8.6 13 5.8 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Lectin_C PF00059.21 RUS76722.1 - 2.4e-83 275.9 24.5 1.3e-18 67.7 2.3 5.8 6 0 0 6 6 6 5 Lectin C-type domain DUF3692 PF12469.8 RUS76722.1 - 0.096 12.9 0.0 23 5.2 0.0 3.2 3 0 0 3 3 3 0 CRISPR-associated protein ASC PF00858.24 RUS76723.1 - 6.5e-97 325.3 8.0 7.9e-80 269.0 2.1 2.3 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel PhaP_Bmeg PF09602.10 RUS76723.1 - 0.0033 17.4 0.9 0.17 11.8 0.4 2.7 2 1 0 2 2 2 2 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Trypsin PF00089.26 RUS76724.1 - 4e-10 39.9 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS76724.1 - 9.5e-08 33.1 0.0 1.9e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain RE_HaeIII PF09556.10 RUS76724.1 - 0.078 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 HaeIII restriction endonuclease Peptidase_S46 PF10459.9 RUS76724.1 - 0.33 9.5 0.4 15 4.0 0.4 2.2 2 0 0 2 2 2 0 Peptidase S46 RhoGEF PF00621.20 RUS76727.1 - 7e-46 156.8 3.0 1.1e-45 156.1 3.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 RUS76727.1 - 5.7e-18 64.8 10.8 1.1e-17 64.0 10.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 RUS76727.1 - 0.00011 22.7 0.6 0.00062 20.2 0.1 2.5 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 RUS76727.1 - 0.0019 18.6 0.2 0.0089 16.4 0.1 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 RUS76727.1 - 0.0026 17.9 5.5 0.0083 16.3 5.5 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 RUS76727.1 - 0.087 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 RUS76727.1 - 0.27 11.7 2.9 0.58 10.6 0.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain I-set PF07679.16 RUS76729.1 - 2.6e-71 235.8 2.3 8.3e-18 64.2 0.0 7.7 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS76729.1 - 4e-69 229.2 8.6 2.1e-13 50.7 0.0 8.2 8 0 0 8 8 8 6 Immunoglobulin domain Ig_2 PF13895.6 RUS76729.1 - 6.3e-42 141.8 5.1 8.4e-11 42.1 0.0 7.2 7 1 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 RUS76729.1 - 4e-39 132.7 3.3 7.3e-08 32.5 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 RUS76729.1 - 2.8e-32 110.9 9.3 2.5e-06 27.7 0.0 6.5 5 2 0 5 5 5 5 Fibronectin type III domain Bravo_FIGEY PF13882.6 RUS76729.1 - 1.5e-17 64.7 2.9 8e-17 62.4 2.9 2.4 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 RUS76729.1 - 1.2e-15 57.6 14.7 0.18 12.0 0.0 10.5 6 5 3 9 9 9 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS76729.1 - 3.3e-13 49.5 2.7 0.0048 16.9 0.0 6.7 8 0 0 8 8 7 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS76729.1 - 1.8e-09 37.0 0.0 0.19 11.3 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS76729.1 - 0.0012 18.8 1.0 21 5.3 0.0 4.8 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS76729.1 - 0.011 15.8 0.3 2.2 8.4 0.0 4.5 6 0 0 6 6 5 0 C17orf99 Ig domain Pur_ac_phosph_N PF16656.5 RUS76729.1 - 0.013 16.1 7.2 0.23 12.0 0.0 4.2 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 RUS76729.1 - 0.19 11.6 1.5 30 4.5 0.0 4.3 4 1 0 4 4 4 0 Tissue factor adh_short_C2 PF13561.6 RUS76732.1 - 1.2e-50 172.3 0.9 1.7e-49 168.5 0.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS76732.1 - 1.8e-45 154.8 4.3 2.7e-43 147.7 4.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS76732.1 - 3.4e-09 36.8 0.5 5.6e-09 36.2 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RUS76732.1 - 0.048 13.5 0.2 0.088 12.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRT_C PF08372.10 RUS76733.1 - 2.3 8.0 7.8 1.7 8.4 6.5 1.4 1 1 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal HLH PF00010.26 RUS76736.1 - 7.9e-18 64.2 0.9 1.4e-17 63.3 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF848 PF05852.11 RUS76736.1 - 0.071 13.2 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Com_YlbF PF06133.11 RUS76736.1 - 0.11 13.1 3.0 0.25 12.0 3.0 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA SAND PF01342.21 RUS76738.1 - 7.2e-28 96.1 0.1 2.4e-27 94.4 0.1 2.0 2 0 0 2 2 2 1 SAND domain DUF4004 PF13171.6 RUS76738.1 - 0.14 12.4 3.9 0.22 11.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) AbiH PF14253.6 RUS76738.1 - 0.3 10.9 0.9 0.43 10.4 0.9 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PAT1 PF09770.9 RUS76739.1 - 2.1e-08 33.0 19.1 5e-07 28.4 0.3 3.9 3 2 0 3 3 3 2 Topoisomerase II-associated protein PAT1 AdenylateSensor PF16579.5 RUS76739.1 - 0.041 14.3 0.5 0.081 13.4 0.5 1.4 1 0 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase E1_DerP2_DerF2 PF02221.15 RUS76740.1 - 3e-05 24.5 0.4 3.4e-05 24.3 0.4 1.1 1 0 0 1 1 1 1 ML domain SAPS PF04499.15 RUS76743.1 - 2.2e-78 264.2 5.1 5.3e-49 167.3 0.3 5.0 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein HEAT_2 PF13646.6 RUS76743.1 - 0.061 13.7 0.1 0.94 9.9 0.1 2.5 1 1 0 1 1 1 0 HEAT repeats WD40 PF00400.32 RUS76744.1 - 4.6e-08 33.6 12.9 0.0087 16.9 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS76744.1 - 0.083 13.2 0.1 0.86 9.9 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Aldolase_II PF00596.21 RUS76745.1 - 2.4e-37 128.7 4.8 4.4e-29 101.7 0.6 2.1 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain MGC-24 PF05283.11 RUS76746.1 - 1.3e-07 32.1 4.7 1.3e-07 32.1 4.7 2.3 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Chordopox_A13L PF05961.11 RUS76746.1 - 0.052 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF485 PF04341.12 RUS76746.1 - 0.29 11.1 0.8 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 RNA_capsid PF03035.14 RUS76746.1 - 5.4 7.0 10.8 1e+02 2.8 10.1 2.4 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein AIG1 PF04548.16 RUS76747.1 - 1.1e-39 136.0 0.1 1.1e-39 136.0 0.1 2.4 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS76747.1 - 2.6e-08 33.9 0.0 1.1e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase UPF0052 PF01933.18 RUS76747.1 - 0.038 13.2 0.2 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 Roc PF08477.13 RUS76747.1 - 0.058 13.6 0.1 0.21 11.8 0.1 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS76747.1 - 0.095 12.6 0.2 0.095 12.6 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase Phi_1 PF04674.12 RUS76747.1 - 2.1 7.6 3.9 1.2 8.4 1.4 1.7 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region Dynamin_N PF00350.23 RUS76747.1 - 6.3 6.8 18.6 3.2 7.8 0.4 4.0 2 2 1 3 3 3 0 Dynamin family LMBR1 PF04791.16 RUS76747.1 - 6.4 5.6 8.7 8 5.2 8.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PDZ PF00595.24 RUS76748.1 - 3.3e-15 56.2 0.0 9.1e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS76748.1 - 4.8e-11 42.3 0.1 1.6e-10 40.6 0.1 2.0 1 0 0 1 1 1 1 PDZ domain RVT_3 PF13456.6 RUS76748.1 - 0.0018 18.1 8.8 0.3 10.9 1.0 3.6 3 0 0 3 3 3 2 Reverse transcriptase-like WW PF00397.26 RUS76748.1 - 0.0019 18.2 0.4 0.0049 16.9 0.4 1.7 1 0 0 1 1 1 1 WW domain APC_N_CC PF16689.5 RUS76748.1 - 0.0071 16.4 5.9 2.1 8.5 0.6 3.5 2 0 0 2 2 2 2 Coiled-coil N-terminus of APC, dimerisation domain Spt4 PF06093.13 RUS76748.1 - 0.0094 16.0 0.2 8.5 6.6 0.0 2.7 2 0 0 2 2 2 2 Spt4/RpoE2 zinc finger DivIVA PF05103.13 RUS76748.1 - 0.013 15.6 28.2 0.64 10.1 10.0 3.0 2 0 0 2 2 2 0 DivIVA protein GH43_C PF16369.5 RUS76748.1 - 0.093 13.4 0.3 10 6.8 0.0 3.1 3 0 0 3 3 3 0 C-terminal lipocalin-like domain EF-hand_7 PF13499.6 RUS76748.1 - 0.11 13.0 0.0 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Cep57_CLD_2 PF14197.6 RUS76748.1 - 0.13 12.4 11.9 1.5 9.0 0.8 4.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 RUS76748.1 - 0.16 12.2 10.3 2 8.7 0.0 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper HU-CCDC81_bac_2 PF18175.1 RUS76748.1 - 0.34 10.8 16.2 1.4 8.9 0.7 5.4 6 0 0 6 6 6 0 CCDC81-like prokaryotic HU domain 2 DUF1192 PF06698.11 RUS76748.1 - 3.6 7.7 12.5 75 3.5 1.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Ribosomal_L22 PF00237.19 RUS76748.1 - 4.2 7.6 8.6 23 5.3 1.5 3.0 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e RILP PF11461.8 RUS76748.1 - 10 6.5 17.6 3.7 7.8 2.5 3.9 3 0 0 3 3 2 0 Rab interacting lysosomal protein Rad60-SLD_2 PF13881.6 RUS76749.1 - 4.1e-28 97.7 0.0 5.1e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RUS76749.1 - 9.9e-06 25.2 0.0 3.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RUS76749.1 - 0.042 14.4 0.0 0.054 14.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain IgGFc_binding PF17517.2 RUS76750.1 - 7.7e-32 110.7 16.2 1.6e-21 76.9 1.9 3.7 3 0 0 3 3 3 2 IgGFc binding protein Nop14 PF04147.12 RUS76750.1 - 9e-06 24.2 47.7 0.00099 17.5 17.4 2.1 2 0 0 2 2 2 2 Nop14-like family Gaa1 PF04114.14 RUS76750.1 - 0.0011 18.0 0.0 0.57 9.1 0.4 2.4 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component RRN3 PF05327.11 RUS76750.1 - 0.0071 15.0 47.6 0.014 13.9 18.6 2.1 2 0 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 DUF1676 PF07898.13 RUS76750.1 - 0.067 13.2 0.2 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PRA1 PF03208.19 RUS76750.1 - 0.55 9.9 7.9 0.81 9.3 1.6 3.0 2 0 0 2 2 2 0 PRA1 family protein Mpp10 PF04006.12 RUS76750.1 - 0.87 7.9 42.3 0.13 10.6 15.1 2.1 2 0 0 2 2 2 0 Mpp10 protein SDA1 PF05285.12 RUS76750.1 - 2.3 7.5 61.3 2.6 7.4 27.1 2.1 2 0 0 2 2 2 0 SDA1 CobT PF06213.12 RUS76750.1 - 4.7 6.5 38.8 1.8 7.9 16.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SDF PF00375.18 RUS76751.1 - 3.3e-27 95.5 2.0 4e-27 95.2 2.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF21 PF01595.20 RUS76753.1 - 5.9e-39 133.6 0.5 1e-38 132.8 0.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RUS76753.1 - 0.00022 21.6 0.2 0.88 10.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 RUS76753.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Tim54 PF11711.8 RUS76754.1 - 0.00018 20.5 14.7 0.0002 20.3 14.7 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 RUS76754.1 - 0.0024 16.7 20.1 0.0025 16.7 20.1 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 RUS76754.1 - 0.004 16.1 10.2 0.0043 16.0 10.2 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 DDHD PF02862.17 RUS76754.1 - 0.0059 16.8 5.5 0.0064 16.7 5.5 1.2 1 0 0 1 1 1 1 DDHD domain Sin_N PF04801.13 RUS76754.1 - 0.017 14.4 13.4 0.019 14.2 13.4 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region SpoIIP PF07454.11 RUS76754.1 - 0.027 13.9 16.6 0.034 13.6 16.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 RUS76754.1 - 0.033 13.4 8.4 0.034 13.4 8.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 RUS76754.1 - 0.038 12.8 14.4 0.042 12.6 14.4 1.1 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 RUS76754.1 - 0.043 12.8 5.7 0.045 12.8 5.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF5308 PF17233.2 RUS76754.1 - 0.048 13.9 2.4 0.061 13.6 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF2151 PF10221.9 RUS76754.1 - 0.17 10.5 15.4 0.18 10.4 15.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 RUS76754.1 - 0.18 10.0 22.5 0.22 9.7 22.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 RUS76754.1 - 0.2 11.9 31.6 0.33 11.2 31.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) BORG_CEP PF14957.6 RUS76754.1 - 0.26 12.4 10.2 0.35 12.1 10.2 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF2828 PF11443.8 RUS76754.1 - 0.33 9.0 25.2 0.39 8.7 25.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spt20 PF12090.8 RUS76754.1 - 0.34 10.5 16.3 0.51 9.9 16.3 1.3 1 0 0 1 1 1 0 Spt20 family ASC PF00858.24 RUS76754.1 - 0.45 9.4 5.7 0.5 9.3 5.7 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel SLC12 PF03522.15 RUS76754.1 - 0.6 9.1 21.3 2.5 7.0 21.9 1.6 2 0 0 2 2 2 0 Solute carrier family 12 AF-4 PF05110.13 RUS76754.1 - 0.64 8.0 34.0 0.74 7.8 34.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Otopetrin PF03189.13 RUS76754.1 - 0.83 8.4 5.0 0.92 8.3 5.0 1.1 1 0 0 1 1 1 0 Otopetrin FGF-BP1 PF06473.12 RUS76754.1 - 0.87 9.4 29.3 1.2 8.9 29.3 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RPOL_N PF14700.6 RUS76754.1 - 1 8.7 26.5 1.3 8.3 26.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SRP-alpha_N PF04086.13 RUS76754.1 - 1 9.2 32.8 1.7 8.5 32.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Vfa1 PF08432.10 RUS76754.1 - 1.4 9.3 41.1 2.2 8.6 41.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paramyxo_ncap PF00973.19 RUS76754.1 - 1.5 7.7 11.8 1.7 7.5 11.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.15 RUS76754.1 - 1.5 7.5 12.7 1.8 7.2 12.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RP-C_C PF11800.8 RUS76754.1 - 1.9 8.5 8.6 2.8 8.0 8.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region NARP1 PF12569.8 RUS76754.1 - 2.1 7.2 36.2 2.7 6.8 36.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YL1 PF05764.13 RUS76754.1 - 2.3 8.2 42.7 3.6 7.6 42.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF4050 PF13259.6 RUS76754.1 - 2.4 8.4 16.3 3.6 7.9 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF4569 PF15133.6 RUS76754.1 - 2.4 7.8 14.8 3.2 7.4 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) ALMT PF11744.8 RUS76754.1 - 3.1 6.5 15.2 3.7 6.3 15.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4551 PF15087.6 RUS76754.1 - 3.2 6.5 14.0 3.6 6.3 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Gti1_Pac2 PF09729.9 RUS76754.1 - 3.2 7.8 21.4 4.8 7.2 21.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DAG_kinase_N PF14513.6 RUS76754.1 - 3.8 7.7 19.5 5.5 7.2 19.5 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CLN3 PF02487.17 RUS76754.1 - 4.1 6.4 11.9 5.1 6.0 11.9 1.1 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 RUS76754.1 - 4.1 7.4 18.8 5.1 7.1 18.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 RUS76754.1 - 4.4 7.0 16.5 5.8 6.6 16.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PS_pyruv_trans PF04230.13 RUS76754.1 - 6.2 6.6 6.1 11 5.8 6.1 1.5 1 1 0 1 1 1 0 Polysaccharide pyruvyl transferase Dsh_C PF12316.8 RUS76754.1 - 6.7 7.1 6.1 8.1 6.8 6.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PA26 PF04636.13 RUS76754.1 - 7.2 5.4 11.2 9.8 5.0 11.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Endostatin PF06482.11 RUS76754.1 - 8.2 5.8 14.7 10 5.5 14.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin OATP PF03137.20 RUS76754.1 - 9 4.4 14.6 13 4.0 14.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rtf2 PF04641.12 RUS76754.1 - 9.5 5.5 39.3 16 4.8 39.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 RUS76754.1 - 9.7 6.6 27.8 15 6.0 27.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RVT_1 PF00078.27 RUS76756.1 - 0.00018 21.1 0.4 0.00061 19.4 0.4 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cyclin_N PF00134.23 RUS76758.1 - 1.7e-42 144.2 1.4 1.1e-41 141.5 0.1 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS76758.1 - 1.4e-34 118.7 1.6 2.7e-34 117.8 1.6 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PDCD7 PF16021.5 RUS76759.1 - 1e-57 195.6 17.6 1e-57 195.6 17.6 1.6 1 1 0 1 1 1 1 Programmed cell death protein 7 ART PF01129.18 RUS76759.1 - 5.1 6.3 9.8 5.9 6.1 0.4 2.4 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase CDC50 PF03381.15 RUS76761.1 - 5.3e-95 318.1 0.3 7.7e-95 317.6 0.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TMEM238 PF15125.6 RUS76761.1 - 4 7.7 13.7 20 5.5 0.1 2.4 2 0 0 2 2 2 0 TMEM238 protein family Diphtheria_C PF02763.14 RUS76762.1 - 0.15 11.7 0.1 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Diphtheria toxin, C domain GlutR_dimer PF00745.20 RUS76762.1 - 0.16 12.5 0.7 40 4.7 0.1 4.2 1 1 3 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain YycC PF14174.6 RUS76762.1 - 0.22 11.3 1.0 5.6 6.9 0.0 3.5 4 0 0 4 4 4 0 YycC-like protein CEL_III_C PF18054.1 RUS76762.1 - 1.7 8.7 5.1 12 5.9 0.9 2.2 1 1 0 2 2 2 0 CEL-III C-terminal IF2_assoc PF08364.11 RUS76762.1 - 8.1 6.8 23.0 35 4.8 0.4 6.9 3 3 2 5 5 5 0 Bacterial translation initiation factor IF-2 associated region EF-hand_7 PF13499.6 RUS76763.1 - 1.3e-15 57.6 0.1 8.3e-11 42.2 0.0 3.2 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS76763.1 - 1.2e-13 49.8 0.2 1.6e-07 30.5 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 RUS76763.1 - 7.7e-13 47.0 0.2 9.7e-06 24.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS76763.1 - 9.7e-13 46.9 0.2 4.6e-05 23.0 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS76763.1 - 8.7e-07 28.7 0.1 0.031 14.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS76763.1 - 0.0012 19.1 0.0 0.0012 19.1 0.0 3.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RUS76763.1 - 0.012 15.4 0.3 1 9.2 0.1 2.8 1 1 1 2 2 2 0 EF hand Flagellin_N PF00669.20 RUS76763.1 - 3 7.9 16.7 3.5 7.7 1.0 2.8 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF812 PF05667.11 RUS76763.1 - 4.4 6.1 33.2 4.7 6.0 31.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 RUS76763.1 - 5.3 6.3 22.0 0.82 9.0 17.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EF-hand_8 PF13833.6 RUS76764.1 - 8e-05 22.4 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS76764.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair PHD_2 PF13831.6 RUS76765.1 - 1.6e-05 24.4 1.3 3.1e-05 23.4 1.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS76765.1 - 0.00014 21.7 0.5 0.00026 20.8 0.5 1.4 1 0 0 1 1 1 1 PHD-finger Ras PF00071.22 RUS76766.1 - 8.2e-36 123.0 0.0 1.1e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS76766.1 - 1.1e-16 61.1 0.0 2.9e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS76766.1 - 1.2e-06 28.1 0.1 2.1e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS76766.1 - 0.0047 16.4 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS76766.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase BTB_2 PF02214.22 RUS76767.1 - 3.2e-21 75.5 0.0 5.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RUS76767.1 - 0.08 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 RUS76767.1 - 0.099 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Mannosyl_trans2 PF04188.13 RUS76768.1 - 5.4e-60 204.0 15.6 8.4e-60 203.3 15.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) SPT6_acidic PF14632.6 RUS76769.1 - 0.25 12.0 2.7 0.38 11.4 2.7 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Adeno_52K PF03052.15 RUS76770.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa AMP-binding PF00501.28 RUS76771.1 - 3.6e-108 361.9 0.0 5.6e-108 361.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS76771.1 - 7.1e-06 26.9 1.2 1.9e-05 25.5 0.3 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Somatomedin_B PF01033.17 RUS76772.1 - 0.013 15.8 14.1 0.013 15.8 14.1 2.2 2 0 0 2 2 2 0 Somatomedin B domain SPT_ssu-like PF11779.8 RUS76773.1 - 5.3e-08 32.4 6.6 7.2e-08 31.9 6.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like ABC_tran PF00005.27 RUS76774.1 - 7.4e-47 159.3 0.0 7.3e-23 81.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 RUS76774.1 - 2.8e-19 70.0 2.6 3e-05 24.0 0.0 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 RUS76774.1 - 2.2e-09 37.2 0.5 2.2e-09 37.2 0.5 2.6 3 0 0 3 3 1 1 ABC transporter SMC_N PF02463.19 RUS76774.1 - 3.2e-09 36.5 0.1 0.089 12.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RUS76774.1 - 6.7e-07 29.0 0.0 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RUS76774.1 - 1.4e-06 29.0 1.3 0.0097 16.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 RUS76774.1 - 1.5e-06 28.2 0.0 0.038 13.7 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 RUS76774.1 - 7.9e-06 26.2 0.1 0.015 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RUS76774.1 - 9.3e-06 25.7 0.0 0.05 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS76774.1 - 3.6e-05 24.2 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 RUS76774.1 - 5e-05 23.5 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RUS76774.1 - 5.1e-05 23.2 0.0 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS76774.1 - 0.00043 20.6 0.1 0.8 10.0 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RUS76774.1 - 0.00065 20.3 0.0 1.4 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RUS76774.1 - 0.0017 18.0 0.0 1.7 8.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 RUS76774.1 - 0.003 18.0 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RUS76774.1 - 0.0043 17.0 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 RUS76774.1 - 0.0049 16.9 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.6 RUS76774.1 - 0.0071 16.4 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2813 PF11398.8 RUS76774.1 - 0.012 14.8 0.0 0.4 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) MukB PF04310.12 RUS76774.1 - 0.014 15.2 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 RUS76774.1 - 0.016 14.8 0.9 1 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 RUS76774.1 - 0.02 14.9 0.1 8.9 6.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RUS76774.1 - 0.025 14.3 0.0 0.44 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 RUS76774.1 - 0.04 13.1 0.2 7.4 5.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Phage_TAC_11 PF11836.8 RUS76774.1 - 0.041 14.0 0.9 0.16 12.1 0.4 2.2 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 RNA_helicase PF00910.22 RUS76774.1 - 0.044 14.2 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RUS76774.1 - 0.045 13.5 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RUS76774.1 - 0.088 12.9 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 RUS76774.1 - 0.11 11.8 0.1 0.95 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 RUS76774.1 - 0.15 11.0 0.1 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 RUS76774.1 - 0.15 11.8 0.0 9.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 RUS76774.1 - 0.2 11.2 0.3 26 4.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CS PF04969.16 RUS76775.1 - 3.8e-05 24.6 0.1 6.7e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 CS domain BTB_2 PF02214.22 RUS76776.1 - 7e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RUS76776.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.8 1 1 1 2 2 2 0 BTB/POZ domain 7tm_1 PF00001.21 RUS76777.1 - 1.1e-11 44.6 9.4 1.7e-11 44.0 9.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS76778.1 - 8.5e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS76778.1 - 5.9e-06 25.8 0.1 8.5e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF5345 PF17280.2 RUS76778.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Lectin_C PF00059.21 RUS76779.1 - 1.7e-13 51.2 0.0 2.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Zn-C2H2_12 PF18112.1 RUS76780.1 - 7.3e-09 35.9 13.7 3.4e-07 30.6 3.0 2.6 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain GOLGA2L5 PF15070.6 RUS76780.1 - 0.00041 19.2 2.6 0.00041 19.2 2.6 2.1 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Fez1 PF06818.15 RUS76780.1 - 0.00045 20.7 15.0 0.00072 20.1 7.5 2.3 2 0 0 2 2 2 1 Fez1 CENP-F_N PF10481.9 RUS76780.1 - 0.0017 18.1 4.6 0.05 13.2 0.2 2.7 2 1 0 2 2 2 1 Cenp-F N-terminal domain DUF4407 PF14362.6 RUS76780.1 - 0.0026 17.2 6.5 0.074 12.4 1.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) RNF220 PF15926.5 RUS76780.1 - 0.004 16.8 1.1 0.1 12.2 0.0 2.9 3 0 0 3 3 2 1 E3 ubiquitin-protein ligase RNF220 DivIC PF04977.15 RUS76780.1 - 0.0084 15.9 15.8 0.035 13.9 0.6 3.5 4 0 0 4 4 3 2 Septum formation initiator GAS PF13851.6 RUS76780.1 - 0.036 13.4 17.5 0.088 12.1 5.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 RUS76780.1 - 0.039 14.2 19.8 0.49 10.6 0.3 3.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-C2H2_4 PF13894.6 RUS76780.1 - 0.051 14.4 3.7 6.6 7.9 0.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ZapB PF06005.12 RUS76780.1 - 0.057 13.9 0.2 0.057 13.9 0.2 3.5 3 0 0 3 3 3 0 Cell division protein ZapB zf-C2H2_12 PF18658.1 RUS76780.1 - 0.059 12.9 0.6 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type V_ATPase_I PF01496.19 RUS76780.1 - 0.091 10.7 3.4 0.093 10.6 0.4 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CorA PF01544.18 RUS76780.1 - 0.2 10.9 1.1 0.4 10.0 0.3 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF812 PF05667.11 RUS76780.1 - 0.22 10.3 7.9 0.57 9.0 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) PRKG1_interact PF15898.5 RUS76780.1 - 0.3 12.0 18.4 0.031 15.2 6.9 2.8 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain Rad50_zn_hook PF04423.14 RUS76780.1 - 0.41 10.5 6.0 0.85 9.5 0.0 3.3 3 0 0 3 3 2 0 Rad50 zinc hook motif UPF0242 PF06785.11 RUS76780.1 - 0.63 10.1 15.1 0.025 14.7 1.4 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 RUS76780.1 - 1.4 9.6 5.4 19 5.8 2.3 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Atg14 PF10186.9 RUS76780.1 - 1.5 7.8 12.6 0.11 11.5 5.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 RUS76780.1 - 2 9.1 20.6 0.68 10.6 1.2 5.3 4 1 1 5 5 5 0 SlyX HMMR_N PF15905.5 RUS76780.1 - 2.1 7.7 20.2 0.19 11.2 1.6 3.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal P4Ha_N PF08336.11 RUS76780.1 - 2.3 8.2 5.4 6.2 6.8 0.4 3.1 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4201 PF13870.6 RUS76780.1 - 2.3 7.9 16.6 0.017 14.8 3.3 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 RUS76780.1 - 2.4 8.4 18.3 3.2 8.0 3.3 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 RUS76780.1 - 2.6 6.9 16.7 0.073 11.9 5.9 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 RUS76780.1 - 3 8.1 13.0 3.5 7.9 0.1 3.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF641 PF04859.12 RUS76780.1 - 3 8.2 12.0 2.2 8.6 4.9 3.2 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 RUS76780.1 - 3.2 8.4 12.2 0.14 12.8 1.1 3.3 2 1 1 3 3 3 0 Initiation control protein YabA Taxilin PF09728.9 RUS76780.1 - 3.4 6.8 12.7 0.063 12.5 2.7 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF745 PF05335.13 RUS76780.1 - 6.5 6.4 15.5 1.4 8.6 7.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TACC_C PF05010.14 RUS76780.1 - 7 6.4 10.9 2.4 7.9 0.5 2.7 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TolA_bind_tri PF16331.5 RUS76780.1 - 7.6 6.7 23.6 0.75 9.9 1.1 4.3 3 1 1 4 4 4 0 TolA binding protein trimerisation FlaC_arch PF05377.11 RUS76780.1 - 8.2 6.9 15.0 1.3 9.5 2.0 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 RUS76780.1 - 9.1 5.7 12.1 8 5.9 9.4 2.2 1 1 1 2 2 2 0 Leucine zipper RT_RNaseH_2 PF17919.1 RUS76781.1 - 1.8e-35 120.9 0.0 3.4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS76781.1 - 2.6e-35 120.9 0.0 4.8e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS76781.1 - 3.8e-05 23.3 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 RUS76781.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Ser_hydrolase PF06821.13 RUS76782.1 - 4.3e-13 49.5 0.0 6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 RUS76782.1 - 2.3e-06 27.4 0.1 0.0008 19.1 0.0 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1057 PF06342.12 RUS76782.1 - 0.0002 20.5 0.0 0.00041 19.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 RUS76782.1 - 0.0029 18.3 0.0 0.0041 17.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.8 RUS76782.1 - 0.049 13.0 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) TIR_2 PF13676.6 RUS76782.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.5 1 1 0 1 1 1 0 TIR domain Abhydrolase_5 PF12695.7 RUS76782.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family EPL1 PF10513.9 RUS76783.1 - 3.3e-14 53.5 1.7 3.3e-14 53.5 1.7 3.4 4 0 0 4 4 4 2 Enhancer of polycomb-like E_Pc_C PF06752.12 RUS76783.1 - 2.5e-06 27.8 17.0 2.5e-06 27.8 17.0 3.7 2 1 1 3 3 3 1 Enhancer of Polycomb C-terminus XRCC4 PF06632.12 RUS76783.1 - 0.0018 17.2 11.7 0.0033 16.4 11.7 1.4 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 polyprenyl_synt PF00348.17 RUS76784.1 - 7.4e-68 228.4 2.1 9.5e-68 228.0 2.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CIDE-N PF02017.15 RUS76784.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 CIDE-N domain NmrA PF05368.13 RUS76785.1 - 2.9e-40 138.3 0.0 3.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RUS76785.1 - 1.2e-19 70.9 0.1 2.1e-19 70.1 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RUS76785.1 - 1.2e-05 24.9 0.5 3.2e-05 23.5 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 RUS76785.1 - 5.2e-05 23.5 0.1 8.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 RUS76785.1 - 0.00048 19.2 0.1 0.00068 18.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 RUS76785.1 - 0.00084 19.5 0.2 0.0016 18.6 0.2 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 RUS76785.1 - 0.0016 18.7 0.1 0.0025 18.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 RUS76785.1 - 0.0069 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 RUS76785.1 - 0.0086 16.0 0.2 0.018 15.0 0.2 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 RUS76785.1 - 0.012 15.0 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 RUS76785.1 - 0.016 14.4 0.1 3.8 6.6 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein adh_short PF00106.25 RUS76785.1 - 0.017 14.6 0.4 0.05 13.1 0.4 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF3168 PF11367.8 RUS76785.1 - 0.04 14.1 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) THF_DHG_CYH_C PF02882.19 RUS76785.1 - 0.11 11.8 0.3 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 RUS76785.1 - 0.16 12.0 0.2 0.32 11.1 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_92 PF01697.27 RUS76787.1 - 5.8e-19 68.8 0.0 9.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS76787.1 - 6.3e-05 23.4 0.0 0.00021 21.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anti-TRAP PF15777.5 RUS76788.1 - 0.027 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein fn3 PF00041.21 RUS76789.1 - 1.2e-08 35.1 0.2 1.8e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Nramp PF01566.18 RUS76790.1 - 1.4e-117 392.7 10.9 1.4e-117 392.7 10.9 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Abhydrolase_1 PF00561.20 RUS76791.1 - 4.4e-26 92.1 0.1 3.1e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS76791.1 - 3.9e-22 79.9 0.0 7.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS76791.1 - 5e-21 75.1 0.1 1.5e-20 73.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 RUS76791.1 - 0.003 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_4 PF08386.10 RUS76791.1 - 0.0057 16.7 0.2 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein DLH PF01738.18 RUS76791.1 - 0.0074 15.9 0.0 0.45 10.0 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 RUS76791.1 - 0.0076 15.9 0.0 0.063 12.9 0.0 2.4 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 RUS76791.1 - 0.0086 15.9 0.0 0.36 10.7 0.0 2.5 3 0 0 3 3 3 1 Serine hydrolase VirJ PF06057.11 RUS76791.1 - 0.033 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 RUS76791.1 - 0.059 13.5 0.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 RUS76791.1 - 0.06 13.2 0.0 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF872 PF05915.12 RUS76792.1 - 5.1e-18 65.3 0.0 6e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF2976 PF11190.8 RUS76792.1 - 0.055 13.3 0.7 0.087 12.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) Phage_holin_3_6 PF07332.11 RUS76792.1 - 0.084 12.9 2.1 0.11 12.5 2.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3185 PF11381.8 RUS76792.1 - 0.093 12.8 4.4 4.6 7.3 4.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) YtpI PF14007.6 RUS76792.1 - 0.13 12.5 1.4 0.18 12.0 1.4 1.2 1 0 0 1 1 1 0 YtpI-like protein DUF3040 PF11239.8 RUS76792.1 - 0.16 12.2 1.2 0.27 11.6 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Shugoshin_C PF07557.11 RUS76794.1 - 4.6e-05 23.1 1.9 4.6e-05 23.1 1.9 4.1 4 0 0 4 4 4 1 Shugoshin C terminus VWA PF00092.28 RUS76796.1 - 4.8e-38 131.1 0.0 8e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS76796.1 - 2.2e-09 37.9 0.0 6.7e-07 29.9 0.0 2.6 2 1 0 2 2 2 2 von Willebrand factor type A domain RNase_T PF00929.24 RUS76797.1 - 2.9e-34 119.0 0.0 5.4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease SAP PF02037.27 RUS76797.1 - 4.3e-08 32.7 0.2 7.9e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 SAP domain TB PF00683.17 RUS76798.1 - 0.021 14.6 5.7 0.058 13.2 5.7 1.8 1 0 0 1 1 1 0 TB domain ET PF01684.16 RUS76798.1 - 0.06 13.7 25.1 0.4 11.0 4.1 2.4 2 0 0 2 2 2 0 ET module Sulfotransfer_2 PF03567.14 RUS76799.1 - 2.4e-22 80.1 4.9 3.7e-21 76.2 1.2 2.4 2 0 0 2 2 2 2 Sulfotransferase family Cauli_VI PF01693.16 RUS76800.1 - 0.0067 16.7 4.7 3.5 8.0 0.1 3.6 1 1 2 3 3 3 3 Caulimovirus viroplasmin Apolipoprotein PF01442.18 RUS76800.1 - 0.051 13.4 1.0 0.1 12.5 1.0 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3678 PF12435.8 RUS76800.1 - 1.2 8.5 28.9 0.92 8.9 1.5 6.0 4 2 2 6 6 6 0 Protein of unknown function (DUF3678) APC_u15 PF16636.5 RUS76800.1 - 2.7 8.5 9.8 9.7 6.7 0.8 2.8 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF3185 PF11381.8 RUS76800.1 - 3.9 7.6 4.3 25 5.0 1.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) Sulfotransfer_2 PF03567.14 RUS76801.1 - 4.6e-15 56.2 0.2 6e-15 55.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4797 PF16051.5 RUS76801.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) 7tm_1 PF00001.21 RUS76802.1 - 2e-55 188.0 19.8 2.9e-55 187.4 19.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS76802.1 - 2.1e-12 47.0 18.1 4.6e-12 45.9 18.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS76802.1 - 0.028 14.2 13.7 0.075 12.8 13.7 1.7 1 1 0 1 1 1 0 Olfactory receptor RE_Alw26IDE PF09665.10 RUS76803.1 - 0.051 12.7 0.1 0.077 12.1 0.1 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) CXCXC PF03128.14 RUS76803.1 - 0.059 13.8 4.5 0.28 11.7 0.1 3.5 3 0 0 3 3 3 0 CXCXC repeat Baculo_VP91_N PF08475.10 RUS76803.1 - 0.14 11.9 0.5 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal CBM_14 PF01607.24 RUS76803.1 - 0.15 12.2 2.9 2.5 8.3 0.1 2.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain 3HBOH PF10605.9 RUS76803.1 - 0.2 9.9 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Cyclin_C_2 PF16899.5 RUS76804.1 - 1.7e-20 73.3 0.1 2.1e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 RUS76804.1 - 2e-08 34.0 0.1 3.6e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS76804.1 - 0.00021 21.3 0.1 0.00068 19.7 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3135 PF11333.8 RUS76804.1 - 0.31 11.3 1.9 0.32 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) ABC_tran_Xtn PF12848.7 RUS76804.1 - 2.7 8.1 9.7 0.23 11.5 2.6 2.5 2 1 0 2 2 2 0 ABC transporter Arf PF00025.21 RUS76805.1 - 1.5e-58 197.1 0.0 1.7e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS76805.1 - 7.3e-15 55.3 0.0 9.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS76805.1 - 9e-14 51.4 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS76805.1 - 9.1e-11 41.5 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS76805.1 - 1.6e-09 37.4 0.0 4.9e-06 26.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS76805.1 - 5.1e-07 29.3 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS76805.1 - 0.00037 20.6 0.0 0.00097 19.2 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2754 PF10953.8 RUS76805.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) NACHT PF05729.12 RUS76805.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 RUS76805.1 - 0.091 13.1 0.1 8.9 6.7 0.0 2.4 2 1 0 3 3 3 0 AAA ATPase domain 6PF2K PF01591.18 RUS76805.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Allexi_40kDa PF05549.11 RUS76806.1 - 0.0039 16.8 7.4 0.0039 16.8 7.4 2.9 1 1 3 4 4 4 1 Allexivirus 40kDa protein Cnn_1N PF07989.11 RUS76806.1 - 0.022 14.9 7.4 0.022 14.9 7.4 4.2 5 2 0 5 5 5 0 Centrosomin N-terminal motif 1 Rnk_N PF14760.6 RUS76806.1 - 0.37 11.3 4.1 8.9 6.9 0.1 2.9 2 0 0 2 2 2 0 Rnk N-terminus Pox_polyA_pol_N PF12630.7 RUS76806.1 - 9.2 6.7 6.9 2 8.8 2.6 2.0 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain COesterase PF00135.28 RUS76808.1 - 5.1e-78 263.2 0.0 2.8e-66 224.5 0.3 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS76808.1 - 1.5e-09 38.0 1.5 4.1e-09 36.6 1.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold CENP-B_dimeris PF09026.10 RUS76809.1 - 0.0068 16.8 11.9 0.0068 16.8 11.9 2.0 2 0 0 2 2 2 1 Centromere protein B dimerisation domain GCIP PF13324.6 RUS76809.1 - 0.18 11.4 2.4 0.28 10.7 2.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 RUS76809.1 - 3.9 7.5 6.1 0.64 10.0 2.0 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 RUS76809.1 - 8.5 5.6 15.9 17 4.6 15.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3194 PF11419.8 RUS76810.1 - 0.094 13.1 2.0 0.85 10.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) F5_F8_type_C PF00754.25 RUS76811.1 - 4.2e-07 30.1 0.0 1.5e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain Sod_Cu PF00080.20 RUS76812.1 - 4e-33 114.6 7.9 4e-33 114.6 7.9 2.9 2 1 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) GIT_CC PF16559.5 RUS76812.1 - 0.046 13.6 1.6 0.079 12.8 1.6 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Presenilin PF01080.17 RUS76812.1 - 0.87 8.3 8.7 1.1 7.9 8.7 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RUS76812.1 - 6.4 5.2 16.0 7.9 4.9 16.0 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 RUS76812.1 - 9.1 4.4 15.0 12 4.0 15.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Mon1 PF03164.14 RUS76813.1 - 2.8e-145 484.4 1.4 3.4e-145 484.1 1.4 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 F5_F8_type_C PF00754.25 RUS76814.1 - 1.3e-08 35.0 0.0 6.8e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain YcgR PF07317.12 RUS76817.1 - 0.068 13.1 0.1 0.66 9.9 0.0 2.4 3 0 0 3 3 3 0 Flagellar regulator YcgR 7tm_1 PF00001.21 RUS76818.1 - 3.5e-18 65.9 10.4 4.1e-18 65.6 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.8 RUS76818.1 - 0.065 13.3 0.7 0.5 10.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function Acyl-CoA_dh_1 PF00441.24 RUS76819.1 - 1e-43 149.1 1.2 1.8e-43 148.3 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS76819.1 - 3.8e-28 98.4 0.0 7.6e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RUS76819.1 - 7.4e-27 93.4 0.0 1.5e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RUS76819.1 - 9.9e-19 67.9 0.1 1.6e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RUS76819.1 - 0.027 14.1 0.0 0.071 12.8 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Synaphin PF05835.12 RUS76820.1 - 5e-40 137.1 16.2 5.9e-40 136.8 16.2 1.0 1 0 0 1 1 1 1 Synaphin protein Vfa1 PF08432.10 RUS76820.1 - 1.4 9.3 10.8 1.8 8.9 10.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 RUS76821.1 - 5.9e-55 186.9 0.0 7e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2678 PF10856.8 RUS76821.1 - 0.0069 16.3 1.3 0.0069 16.3 1.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2678) Neur_chan_LBD PF02931.23 RUS76821.1 - 0.0088 15.5 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain BRI3BP PF14965.6 RUS76821.1 - 3.1 7.3 7.4 0.34 10.4 2.5 1.8 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Peptidase_S8 PF00082.22 RUS76822.1 - 7.8e-49 166.5 1.7 1e-48 166.2 1.7 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RUS76822.1 - 7.5e-25 86.8 0.1 1.3e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 RUS76822.1 - 1.2e-06 28.3 34.3 1.2e-06 28.3 34.3 2.3 3 0 0 3 3 3 1 Growth factor receptor domain IV Furin-like PF00757.20 RUS76822.1 - 0.011 15.7 29.7 0.03 14.2 28.9 2.3 1 1 0 1 1 1 0 Furin-like cysteine rich region VSP PF03302.13 RUS76822.1 - 0.31 9.8 33.1 0.047 12.6 6.2 2.7 2 1 1 3 3 3 0 Giardia variant-specific surface protein zf-H2C2_5 PF13909.6 RUS76823.1 - 0.077 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain IQ PF00612.27 RUS76824.1 - 2.4e-11 42.4 15.7 0.00042 19.9 3.5 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Antigen_Bd37 PF11641.8 RUS76824.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein FadA PF09403.10 RUS76824.1 - 7.4 7.1 10.2 0.14 12.7 0.5 2.9 2 0 0 2 2 2 0 Adhesion protein FadA BTB_2 PF02214.22 RUS76825.1 - 2e-18 66.5 0.0 4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RUS76825.1 - 5.9e-05 23.1 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SNF PF00209.18 RUS76826.1 - 1.7e-166 555.0 24.7 8.4e-135 450.4 17.7 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family Comm PF15957.5 RUS76826.1 - 0.016 15.6 1.0 7.9 6.9 0.0 3.9 3 1 0 3 3 3 0 Commissureless Cadherin PF00028.17 RUS76828.1 - 2.1e-95 313.4 6.0 4.4e-18 65.5 0.1 7.4 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS76828.1 - 3.4e-15 55.6 0.1 3.1e-09 36.5 0.1 5.6 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 RUS76828.1 - 6e-05 23.0 8.6 1.9 8.5 0.0 5.6 5 0 0 5 5 5 3 Cadherin-like SQAPI PF16845.5 RUS76828.1 - 0.0095 16.3 2.0 1.7 9.0 0.2 4.2 4 1 0 4 4 4 1 Aspartic acid proteinase inhibitor Cadherin_4 PF17803.1 RUS76828.1 - 0.33 11.6 27.6 0.42 11.3 0.1 5.6 6 0 0 6 6 6 0 Bacterial cadherin-like domain KH_1 PF00013.29 RUS76830.1 - 2.6e-28 97.6 5.6 7.2e-15 54.6 0.5 4.7 5 0 0 5 5 5 3 KH domain SAM_1 PF00536.30 RUS76830.1 - 1.6e-11 44.5 0.0 3.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS76830.1 - 3.4e-10 39.9 0.1 9.1e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 RUS76830.1 - 3.2e-06 27.5 0.4 0.0093 16.4 0.0 3.7 3 1 1 4 4 4 2 GLD-3 KH domain 5 KH_2 PF07650.17 RUS76830.1 - 0.17 11.7 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 KH domain TFIIA PF03153.13 RUS76830.1 - 6 6.8 26.6 0.13 12.3 18.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 RUS76831.1 - 1.3e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76831.1 - 0.059 12.6 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 RUS76831.1 - 0.061 12.7 0.2 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RUS76831.1 - 0.21 10.5 0.2 0.31 10.0 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mad3_BUB1_I PF08311.12 RUS76832.1 - 2.3e-40 137.4 0.1 4e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mito_fiss_reg PF05308.11 RUS76832.1 - 0.003 17.7 0.7 0.003 17.7 0.7 3.0 3 1 1 4 4 4 1 Mitochondrial fission regulator Mad3_BUB1_I_2 PF17014.5 RUS76832.1 - 0.0034 17.5 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein SIS PF01380.22 RUS76833.1 - 3.2e-59 198.5 0.0 8.1e-35 119.5 0.0 3.6 2 1 1 3 3 3 3 SIS domain GATase_6 PF13522.6 RUS76833.1 - 8.3e-16 58.4 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RUS76833.1 - 1.3e-11 44.5 0.0 3.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RUS76833.1 - 0.00012 21.1 0.1 0.0002 20.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RUS76833.1 - 0.0013 18.7 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 SIS domain DUF2294 PF10057.9 RUS76833.1 - 0.067 13.3 0.2 0.067 13.3 0.2 2.8 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2294) GATase_2 PF00310.21 RUS76833.1 - 0.075 11.7 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RCC1 PF00415.18 RUS76835.1 - 1e-78 259.8 17.9 1.2e-13 51.5 0.2 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 RUS76835.1 - 3.4e-59 200.8 0.0 5.6e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 RUS76835.1 - 6.7e-38 127.8 34.7 6e-08 32.3 0.2 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 RUS76835.1 - 0.11 12.8 2.5 1.1e+02 3.2 0.0 4.3 3 1 1 4 4 4 0 Putative heavy-metal chelation Lectin_C PF00059.21 RUS76836.1 - 4.1e-69 230.2 26.8 1.8e-19 70.4 4.9 5.2 5 0 0 5 5 5 4 Lectin C-type domain ApeC PF16977.5 RUS76836.1 - 2.1e-44 152.0 0.5 4.6e-44 150.8 0.5 1.7 1 0 0 1 1 1 1 C-terminal domain of apextrin Astacin PF01400.24 RUS76836.1 - 3.4e-24 85.5 0.2 1e-23 83.9 0.2 1.9 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kringle PF00051.18 RUS76836.1 - 9.7e-10 38.6 6.6 4.8e-09 36.4 6.6 2.3 1 0 0 1 1 1 1 Kringle domain CUB PF00431.20 RUS76836.1 - 1e-07 32.3 1.0 1.8e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 CUB domain Sushi PF00084.20 RUS76836.1 - 5.8e-05 23.6 2.9 0.061 13.9 0.3 3.6 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Chordopox_A33R PF05966.12 RUS76836.1 - 0.00044 19.6 3.6 0.74 9.1 0.0 3.5 3 0 0 3 3 3 2 Chordopoxvirus A33R protein DUF3439 PF11921.8 RUS76836.1 - 3.4 7.7 17.1 8.7 6.3 17.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ig_3 PF13927.6 RUS76837.1 - 5.8e-12 46.0 0.5 8.3e-07 29.5 0.0 4.5 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS76837.1 - 7.7e-08 32.6 0.1 1.3e-05 25.4 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RUS76837.1 - 4.3e-07 29.9 0.0 4e-05 23.6 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Lectin_C PF00059.21 RUS76837.1 - 2.3e-05 25.1 0.0 0.0001 23.0 0.0 2.3 1 0 0 1 1 1 1 Lectin C-type domain fn3 PF00041.21 RUS76837.1 - 4.5e-05 23.7 0.1 0.00019 21.7 0.1 2.1 1 0 0 1 1 1 1 Fibronectin type III domain Shisa PF13908.6 RUS76837.1 - 0.0014 18.9 0.7 0.0044 17.3 0.7 1.8 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ig PF00047.25 RUS76837.1 - 0.0015 18.7 0.1 0.42 10.8 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin domain EphA2_TM PF14575.6 RUS76837.1 - 0.0022 18.9 0.2 0.0089 16.9 0.2 2.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 RUS76837.1 - 0.0052 17.0 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Protein melan-A MAP17 PF15807.5 RUS76837.1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.8 2 1 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SID-1_RNA_chan PF13965.6 RUS76837.1 - 0.024 13.1 4.1 0.04 12.3 4.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2500 PF10694.9 RUS76837.1 - 0.081 13.4 1.4 0.26 11.8 0.4 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2500) DUF443 PF04276.12 RUS76837.1 - 0.14 11.9 0.9 0.27 11.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Vpu PF00558.19 RUS76837.1 - 0.17 11.7 0.4 0.37 10.6 0.4 1.5 1 0 0 1 1 1 0 Vpu protein O-antigen_lig PF13425.6 RUS76837.1 - 0.21 10.3 1.2 0.35 9.6 1.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAM176 PF14851.6 RUS76837.1 - 0.32 10.6 2.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 RUS76837.1 - 1.2 10.1 7.9 0.16 12.9 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 RUS76837.1 - 2.5 8.0 8.1 1.7 8.6 5.7 2.0 1 1 1 2 2 2 0 TMEM154 protein family Insulin_TMD PF17870.1 RUS76837.1 - 3.8 7.7 7.0 8.8 6.5 7.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Lectin_C PF00059.21 RUS76838.1 - 3.3e-09 37.4 0.2 3.3e-09 37.4 0.2 3.4 3 0 0 3 3 3 1 Lectin C-type domain Ig_3 PF13927.6 RUS76838.1 - 1.2e-06 29.0 0.8 0.22 12.1 0.1 4.5 4 1 0 4 4 4 2 Immunoglobulin domain DUF4064 PF13273.6 RUS76838.1 - 0.0033 17.7 0.1 0.0071 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) fn3 PF00041.21 RUS76838.1 - 0.014 15.7 0.0 0.055 13.8 0.0 2.0 2 0 0 2 2 2 0 Fibronectin type III domain TMEM154 PF15102.6 RUS76838.1 - 0.014 15.3 0.3 0.014 15.3 0.3 2.4 2 0 0 2 2 2 0 TMEM154 protein family I-set PF07679.16 RUS76838.1 - 0.015 15.4 4.4 0.87 9.7 0.2 3.9 3 1 0 3 3 3 0 Immunoglobulin I-set domain SRTM1 PF15872.5 RUS76838.1 - 0.091 12.9 0.3 0.27 11.4 0.3 1.7 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Tmemb_9 PF05434.11 RUS76838.1 - 0.099 12.5 0.0 0.099 12.5 0.0 2.6 3 0 0 3 3 3 0 TMEM9 EphA2_TM PF14575.6 RUS76838.1 - 0.38 11.7 2.8 0.61 11.0 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HNOBA PF07701.14 RUS76839.1 - 2.8e-58 196.9 0.3 5.5e-58 196.0 0.3 1.5 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 RUS76839.1 - 4.8e-52 176.2 0.0 8.4e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 RUS76839.1 - 2.1e-51 174.1 0.1 3.3e-51 173.5 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Acyl-CoA_dh_1 PF00441.24 RUS76840.1 - 5.9e-41 140.2 7.1 7.4e-39 133.3 1.9 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS76840.1 - 8.7e-26 90.0 0.0 1.9e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS76840.1 - 4e-24 85.4 0.0 1.1e-23 84.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS76840.1 - 4.1e-13 49.7 0.4 5.8e-11 42.8 0.1 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF789 PF05623.12 RUS76840.1 - 0.76 9.4 2.8 1.2 8.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Gal-bind_lectin PF00337.22 RUS76841.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin Gal-bind_lectin PF00337.22 RUS76842.1 - 0.00034 20.1 0.2 0.00054 19.5 0.2 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 RUS76843.1 - 0.00017 21.2 0.0 0.0013 18.3 0.0 2.2 1 1 0 1 1 1 1 Galactoside-binding lectin Ribosomal_L35p PF01632.19 RUS76844.1 - 0.24 11.9 0.0 0.24 11.9 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein L35 DUF1364 PF07102.12 RUS76845.1 - 0.015 15.1 0.6 0.046 13.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) eIF-3_zeta PF05091.12 RUS76847.1 - 7.7e-144 480.5 9.1 8.6e-144 480.3 9.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_III_AF PF09581.10 RUS76847.1 - 0.42 10.6 2.3 0.76 9.8 2.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Beach PF02138.18 RUS76849.1 - 5.3e-121 403.2 1.2 5.3e-121 403.2 1.2 1.8 2 0 0 2 2 2 1 Beige/BEACH domain DUF4800 PF16057.5 RUS76849.1 - 2.9e-93 311.8 8.4 4.6e-93 311.2 8.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF4704 PF15787.5 RUS76849.1 - 1.5e-31 109.7 3.5 3.5e-31 108.5 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 RUS76849.1 - 1.6e-21 76.3 1.4 9.8e-21 73.7 1.4 2.5 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RUS76849.1 - 1.8e-05 25.4 1.6 0.0012 19.6 0.3 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Laminin_G_3 PF13385.6 RUS76849.1 - 0.003 17.7 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily IBN_N PF03810.19 RUS76849.1 - 0.024 14.6 0.0 0.086 12.8 0.0 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-B_box PF00643.24 RUS76851.1 - 5.1e-12 45.8 21.1 4e-06 26.9 8.4 2.3 2 0 0 2 2 2 2 B-box zinc finger ENT PF03735.14 RUS76851.1 - 0.0053 16.8 0.3 0.017 15.2 0.3 1.9 1 0 0 1 1 1 1 ENT domain Spectrin PF00435.21 RUS76851.1 - 0.012 16.1 6.0 0.015 15.8 1.9 2.5 2 0 0 2 2 2 0 Spectrin repeat IBR PF01485.21 RUS76851.1 - 0.013 15.7 11.4 0.12 12.6 0.4 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CEBP_ZZ PF16366.5 RUS76851.1 - 0.035 14.4 3.9 0.035 14.4 3.9 2.3 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Apolipoprotein PF01442.18 RUS76851.1 - 0.041 13.8 5.5 0.097 12.5 5.5 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.13 RUS76851.1 - 0.085 13.4 5.7 0.28 11.7 1.5 3.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain UPF0242 PF06785.11 RUS76851.1 - 0.28 11.3 7.2 0.3 11.2 6.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prok-RING_1 PF14446.6 RUS76851.1 - 0.7 9.9 10.2 2.5 8.1 1.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Exonuc_VII_L PF02601.15 RUS76851.1 - 1.1 8.8 7.9 2 7.9 7.9 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 RUS76851.1 - 1.4 8.9 6.5 4.1 7.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SKA2 PF16740.5 RUS76851.1 - 4.3 7.1 12.1 5.8 6.7 1.6 3.4 2 1 2 4 4 4 0 Spindle and kinetochore-associated protein 2 PHD PF00628.29 RUS76851.1 - 9.1 6.3 15.4 2.3 8.2 3.9 2.6 2 0 0 2 2 2 0 PHD-finger TPR_1 PF00515.28 RUS76852.1 - 2e-36 122.3 37.8 2.2e-08 33.6 0.0 9.4 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 RUS76852.1 - 5.7e-34 113.5 30.4 0.00018 21.4 0.1 9.1 9 1 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 RUS76852.1 - 1.9e-23 82.3 7.7 7e-23 80.5 7.7 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 RUS76852.1 - 6.3e-19 67.4 10.6 5.5e-07 29.2 1.6 6.5 5 1 1 6 6 6 4 TPR repeat TPR_12 PF13424.6 RUS76852.1 - 5.2e-18 65.1 21.7 0.00023 21.4 0.1 7.4 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 RUS76852.1 - 4.1e-16 57.8 27.4 0.0025 17.9 0.0 9.2 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS76852.1 - 3.6e-14 53.1 9.1 0.0073 16.9 0.0 5.6 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 RUS76852.1 - 8.4e-14 51.1 4.7 0.59 11.1 0.0 7.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS76852.1 - 1.6e-13 50.9 12.1 0.0052 17.3 0.2 5.7 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS76852.1 - 6.2e-08 32.1 8.0 0.42 10.7 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS76852.1 - 1.2e-07 31.9 16.6 0.0023 18.4 0.0 7.4 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS76852.1 - 2.7e-07 30.5 14.6 0.0062 16.8 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS76852.1 - 4.2e-07 30.1 29.4 0.0018 18.5 1.6 4.8 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RUS76852.1 - 6.8e-05 22.9 7.3 3.1 8.0 0.4 5.1 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 RUS76852.1 - 0.00016 21.6 2.4 0.95 9.5 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS76852.1 - 0.0006 19.3 1.5 0.0039 16.6 0.3 2.7 2 1 1 3 3 3 1 MalT-like TPR region Rapsyn_N PF10579.9 RUS76852.1 - 0.00079 19.5 3.7 0.92 9.6 0.0 4.8 4 1 1 5 5 5 1 Rapsyn N-terminal myristoylation and linker region Mhr1 PF12829.7 RUS76852.1 - 0.11 12.5 0.1 0.33 11.1 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination RPN7 PF10602.9 RUS76852.1 - 0.24 11.1 13.3 1.4 8.6 0.2 3.6 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 RUS76852.1 - 0.28 11.1 18.3 17 5.4 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2284 PF10050.9 RUS76852.1 - 1.2 8.8 6.3 0.26 11.0 0.1 2.7 2 1 1 3 3 3 0 Predicted metal-binding protein (DUF2284) MIT PF04212.18 RUS76852.1 - 2.2 8.4 22.7 6.2 7.0 0.0 7.0 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 RUS76854.1 - 5.3e-68 229.2 0.0 7.3e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76854.1 - 6.5e-45 153.4 0.0 9.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS76854.1 - 2.7e-07 30.2 0.0 6.6e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PB1 PF00564.24 RUS76854.1 - 2e-05 24.4 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 RUS76854.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS76854.1 - 0.027 14.4 0.1 6 6.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RsfS PF02410.15 RUS76856.1 - 1.4e-19 70.4 0.0 3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CWC25 PF12542.8 RUS76857.1 - 3e-17 63.4 0.2 3e-17 63.4 0.2 5.8 3 1 1 4 4 4 1 Pre-mRNA splicing factor Peptidase_M28 PF04389.17 RUS76857.1 - 0.015 15.0 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase family M28 Dexa_ind PF15198.6 RUS76858.1 - 0.043 13.9 2.4 0.054 13.6 2.4 1.1 1 0 0 1 1 1 0 Dexamethasone-induced HCO3_cotransp PF00955.21 RUS76859.1 - 3e-182 607.0 18.0 5.9e-181 602.7 18.0 2.0 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RUS76859.1 - 2.6e-98 329.1 0.3 2.6e-98 329.1 0.3 1.7 2 0 0 2 2 2 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 RUS76859.1 - 6.9e-05 22.8 0.1 0.0004 20.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF3149 PF11346.8 RUS76859.1 - 0.071 12.7 0.1 0.49 10.1 0.1 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PAN_1 PF00024.26 RUS76860.1 - 0.00045 20.1 0.6 0.00065 19.6 0.6 1.3 1 0 0 1 1 1 1 PAN domain Metallothi_Euk2 PF12809.7 RUS76860.1 - 0.051 13.8 0.1 0.085 13.1 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein Ribosomal_L37 PF08561.10 RUS76861.1 - 1.4e-09 38.5 0.1 1.8e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 PEX11 PF05648.14 RUS76862.1 - 4.3e-44 150.6 2.8 5e-44 150.4 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DEAD PF00270.29 RUS76863.1 - 1.4e-48 165.0 0.0 3.1e-48 163.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS76863.1 - 4.2e-28 97.9 0.1 1.4e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS76863.1 - 5.8e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RUS76863.1 - 0.00026 20.3 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PT PF04886.12 RUS76865.1 - 4e-11 42.3 0.0 0.019 14.5 0.0 4.4 1 1 0 1 1 1 1 PT repeat Homeodomain PF00046.29 RUS76866.1 - 5.1e-20 71.1 2.0 8.6e-20 70.3 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS76866.1 - 1.7e-05 24.6 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF1658 PF07871.11 RUS76868.1 - 1.4 9.0 5.0 6.1 7.0 5.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) NIF3 PF01784.18 RUS76869.1 - 7.1e-68 228.9 0.0 9.3e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Kazal_2 PF07648.15 RUS76870.1 - 1.3e-23 82.9 22.8 7.7e-10 38.7 4.6 3.3 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS76870.1 - 1e-17 63.8 25.5 1.9e-08 34.2 5.6 3.3 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain CBM_14 PF01607.24 RUS76871.1 - 5.3e-21 74.5 20.8 2e-11 43.9 8.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain ATG13 PF10033.9 RUS76871.1 - 0.17 11.5 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 13 CBM_19 PF03427.13 RUS76871.1 - 3.6 7.6 14.7 1.2 9.2 3.4 3.7 2 2 1 3 3 3 0 Carbohydrate binding domain (family 19) PAN_3 PF08277.12 RUS76872.1 - 8.1e-12 44.8 16.6 0.16 11.8 0.3 6.0 1 1 7 8 8 8 8 PAN-like domain MFS_1 PF07690.16 RUS76873.1 - 9e-16 57.7 15.6 8.4e-09 34.8 13.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily BCAS2 PF05700.11 RUS76874.1 - 1.4e-77 260.0 4.5 1.6e-77 259.8 4.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EzrA PF06160.12 RUS76874.1 - 0.0023 16.2 3.4 0.023 12.9 0.5 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Csm1_N PF18504.1 RUS76874.1 - 0.036 14.4 2.4 0.036 14.4 2.4 2.1 3 0 0 3 3 3 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 RUS76874.1 - 0.043 13.3 9.2 0.021 14.3 6.9 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Sirohm_synth_C PF14823.6 RUS76874.1 - 0.061 13.0 0.7 0.14 11.8 0.7 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Exonuc_VII_L PF02601.15 RUS76874.1 - 0.066 12.8 1.3 0.084 12.4 1.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD PF14073.6 RUS76874.1 - 0.16 11.9 9.5 0.94 9.5 9.5 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 FlaC_arch PF05377.11 RUS76874.1 - 0.17 12.3 4.3 0.33 11.4 0.3 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) tRNA_anti-codon PF01336.25 RUS76875.1 - 0.005 16.8 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FMO-like PF00743.19 RUS76876.1 - 1.8e-168 561.3 0.0 2.2e-168 561.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS76876.1 - 1.3e-19 70.6 0.0 4.6e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS76876.1 - 1.2e-12 47.7 0.0 3.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS76876.1 - 3.8e-11 42.7 0.4 2.5e-08 33.4 0.0 3.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 RUS76876.1 - 2.1e-05 25.0 0.0 0.0032 18.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS76876.1 - 0.00023 21.3 0.1 0.00066 19.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS76876.1 - 0.0025 17.4 2.0 0.13 11.8 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 RUS76876.1 - 0.0053 16.8 2.4 6.4 6.7 0.1 4.1 2 2 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 RUS76876.1 - 0.01 15.1 0.3 0.54 9.4 0.0 2.9 3 0 0 3 3 3 1 Thi4 family MAT1 PF06391.13 RUS76877.1 - 4.7e-39 134.3 25.1 1.2e-38 133.0 25.1 1.6 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 RUS76877.1 - 4.2e-13 49.0 4.4 7.3e-13 48.2 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS76877.1 - 6.3e-05 22.9 5.3 0.00015 21.7 5.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 RUS76877.1 - 0.00029 20.9 7.7 0.0007 19.7 0.7 2.5 1 1 1 2 2 2 1 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 RUS76877.1 - 0.00057 19.8 5.5 0.0017 18.3 5.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS76877.1 - 0.0014 18.4 4.6 0.0038 17.1 4.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS76877.1 - 0.005 17.2 5.3 0.011 16.1 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 RUS76877.1 - 0.0071 16.1 3.9 0.017 14.9 0.2 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF2309 PF10070.9 RUS76877.1 - 0.013 13.9 0.3 0.014 13.8 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) zf-C3HC4_2 PF13923.6 RUS76877.1 - 0.02 14.7 6.4 0.072 12.9 6.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS76877.1 - 0.027 14.3 8.2 0.5 10.3 8.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS76877.1 - 0.24 11.6 6.0 0.66 10.2 6.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 RUS76877.1 - 0.24 11.4 3.0 0.54 10.3 3.0 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.14 RUS76877.1 - 0.35 10.6 5.0 0.69 9.6 5.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger Exonuc_VII_L PF02601.15 RUS76877.1 - 0.56 9.7 7.0 0.71 9.4 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 RUS76877.1 - 0.73 9.9 8.9 0.2 11.8 4.9 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DZR PF12773.7 RUS76877.1 - 0.78 9.8 4.5 4.4 7.4 4.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon VIT1 PF01988.19 RUS76877.1 - 1.6 8.6 3.4 2.3 8.0 3.4 1.2 1 0 0 1 1 1 0 VIT family GPCR_chapero_1 PF11904.8 RUS76877.1 - 2.1 7.7 8.4 2.8 7.3 8.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone O-antigen_lig PF13425.6 RUS76877.1 - 2.2 7.0 6.4 2.9 6.6 6.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Baculo_IE-1 PF05290.11 RUS76877.1 - 3.6 7.5 7.6 0.33 10.9 2.3 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF501 PF04417.12 RUS76877.1 - 9.4 6.0 7.9 9.9 6.0 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF501) Ion_trans_2 PF07885.16 RUS76878.1 - 3.4e-35 119.8 16.8 3.5e-18 65.3 0.7 3.1 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS76878.1 - 1.6e-06 27.5 9.7 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 2 Ion transport protein PIF1 PF05970.14 RUS76879.1 - 8.2e-71 239.1 0.2 3.3e-68 230.5 0.2 2.7 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 RUS76879.1 - 2.6e-21 76.2 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS76879.1 - 1.4e-08 35.2 0.0 4.7e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS76879.1 - 5e-05 23.6 0.1 0.00024 21.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RUS76879.1 - 0.00032 20.5 0.1 0.00091 19.0 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 RUS76879.1 - 0.0014 19.1 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 RUS76879.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 RUS76879.1 - 0.0054 14.7 0.3 0.01 13.8 0.0 1.5 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 RUS76879.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.27 RUS76879.1 - 0.0082 16.7 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.21 RUS76879.1 - 0.01 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS76879.1 - 0.015 15.3 0.0 0.086 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RUS76879.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 RUS76879.1 - 0.02 14.6 0.4 2.1 8.0 0.1 3.3 4 1 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 RUS76879.1 - 0.044 14.2 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RUS76879.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 RUS76879.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RUS76879.1 - 0.096 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 RUS76879.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain 7TM_GPCR_Srsx PF10320.9 RUS76881.1 - 0.0048 16.3 1.2 0.0052 16.2 1.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CoA_binding_3 PF13727.6 RUS76881.1 - 2.3 8.2 7.0 3.2 7.8 2.2 2.0 1 1 1 2 2 2 0 CoA-binding domain TIR_2 PF13676.6 RUS76883.1 - 3.8e-31 108.2 0.0 8.1e-09 36.1 0.0 4.4 4 0 0 4 4 4 4 TIR domain SAM_2 PF07647.17 RUS76883.1 - 1.3e-08 34.8 0.4 2.8e-08 33.7 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TIR PF01582.20 RUS76883.1 - 5e-06 26.4 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 TIR domain SAM_1 PF00536.30 RUS76883.1 - 7.7e-06 26.3 0.8 1.6e-05 25.3 0.8 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) VWD PF00094.25 RUS76884.1 - 1e-13 51.9 1.2 3.1e-13 50.3 1.2 1.9 1 0 0 1 1 1 1 von Willebrand factor type D domain PI_PP_I PF18363.1 RUS76884.1 - 1.1 9.5 4.6 1.6 9.0 0.8 3.3 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain Fib_alpha PF08702.10 RUS76884.1 - 6.5 6.9 9.8 73 3.5 0.2 4.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Vitellogenin_N PF01347.22 RUS76885.1 - 3.1e-75 253.8 10.4 5.4e-54 183.7 4.5 2.1 2 0 0 2 2 2 2 Lipoprotein amino terminal region DUF1943 PF09172.11 RUS76885.1 - 1.1e-24 87.3 0.0 1.1e-24 87.3 0.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1943) HlyIII PF03006.20 RUS76886.1 - 1.4e-35 123.0 22.2 1.4e-35 123.0 22.2 1.3 2 0 0 2 2 2 1 Haemolysin-III related Pkinase_Tyr PF07714.17 RUS76887.1 - 1.8e-92 309.3 0.0 2.8e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS76887.1 - 3.9e-50 170.7 0.0 7.7e-49 166.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Focal_AT PF03623.13 RUS76887.1 - 6.5e-47 158.9 1.6 2.2e-46 157.1 1.6 1.9 1 0 0 1 1 1 1 Focal adhesion targeting region FERM_N_2 PF18038.1 RUS76887.1 - 2.1e-17 63.8 0.3 8.2e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 RUS76887.1 - 1e-11 45.3 1.9 2.8e-11 43.9 0.3 2.4 2 0 0 2 2 2 1 FERM central domain Haspin_kinase PF12330.8 RUS76887.1 - 0.00074 18.6 0.1 0.0017 17.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FERM_F2 PF18377.1 RUS76887.1 - 0.00094 19.1 0.8 0.0024 17.8 0.8 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain Kinase-like PF14531.6 RUS76887.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like FERM_f0 PF16511.5 RUS76887.1 - 0.07 13.5 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM DUF3306 PF11748.8 RUS76887.1 - 0.34 11.8 0.1 0.34 11.8 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3306) ABC_membrane_2 PF06472.15 RUS76888.1 - 7.2e-95 317.4 6.9 1.2e-94 316.8 6.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RUS76888.1 - 1.5e-19 70.9 0.0 5.6e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RUS76888.1 - 0.00029 20.3 0.2 0.3 10.5 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS76888.1 - 0.00084 19.9 0.4 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RUS76888.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 RUS76888.1 - 0.0072 16.3 0.0 0.027 14.4 0.0 1.9 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 RUS76888.1 - 0.012 15.4 0.0 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS76888.1 - 0.028 14.8 0.1 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 RUS76888.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 RUS76888.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS76888.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RUS76888.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase XRCC1_N PF01834.16 RUS76889.1 - 5.3e-65 218.0 0.1 9.1e-65 217.2 0.1 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT_2 PF16589.5 RUS76889.1 - 7.3e-22 77.6 0.0 5.1e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RUS76889.1 - 2e-18 66.5 0.0 9e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RUS76889.1 - 1.5e-10 40.9 0.0 2.1e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 RUS76889.1 - 3.4e-06 27.3 0.0 0.00067 19.9 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 RUS76889.1 - 0.075 12.9 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PDZ PF00595.24 RUS76890.1 - 2.6e-14 53.3 0.5 3.7e-14 52.8 0.5 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS76890.1 - 1e-12 47.7 0.7 1.6e-12 47.1 0.7 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS76890.1 - 2.9e-07 30.7 0.1 3.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 PDZ domain Amidase_6 PF12671.7 RUS76890.1 - 0.00037 20.7 0.0 0.00042 20.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidase domain GRASP55_65 PF04495.14 RUS76890.1 - 0.093 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain HTH_psq PF05225.16 RUS76892.1 - 3.6e-10 39.4 0.4 1.2e+02 2.6 0.0 9.9 10 0 0 10 10 10 0 helix-turn-helix, Psq domain HTH_36 PF13730.6 RUS76892.1 - 0.11 12.4 1.6 1.7e+02 2.3 0.1 6.2 4 2 0 4 4 4 0 Helix-turn-helix domain Churchill PF06573.11 RUS76892.1 - 0.53 10.6 4.2 4.3 7.7 0.1 3.2 4 0 0 4 4 4 0 Churchill protein Hydrolase_like PF13242.6 RUS76893.1 - 5e-20 71.4 0.0 2.1e-19 69.4 0.0 2.0 1 1 1 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 RUS76893.1 - 2.8e-07 30.8 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS76893.1 - 9.2e-07 29.4 0.0 1.2e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RUS76893.1 - 0.0063 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase RVT_1 PF00078.27 RUS76894.1 - 2.4e-11 43.6 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLS PF14611.6 RUS76894.1 - 0.09 12.6 2.2 0.16 11.8 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator YrhC PF14143.6 RUS76894.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 YrhC-like protein Lin-8 PF03353.15 RUS76894.1 - 0.15 11.6 1.9 0.22 11.1 1.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cornifin PF02389.15 RUS76896.1 - 4.9e-55 185.4 0.0 4.7e-08 33.3 0.0 6.4 1 1 7 8 8 8 8 Cornifin (SPRR) family CPSF73-100_C PF11718.8 RUS76897.1 - 1.6e-50 171.6 0.0 2.9e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 RUS76897.1 - 1e-31 109.4 0.0 2.6e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 RUS76897.1 - 1.9e-21 76.4 0.0 4.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 RUS76897.1 - 7.2e-21 75.1 0.0 1.5e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 RUS76897.1 - 2.3e-19 69.1 0.0 4.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RUS76897.1 - 7.1e-08 32.2 0.3 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS76897.1 - 4.4e-07 29.9 0.2 4.1e-05 23.5 0.0 3.2 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 RUS76897.1 - 1.1e-05 24.8 0.1 2.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Putative beta-lactamase-like family FAD_binding_7 PF03441.14 RUS76899.1 - 5.8e-81 270.8 1.6 8e-81 270.4 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RUS76899.1 - 1.8e-43 148.4 0.0 3.3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase p12I PF12233.8 RUS76899.1 - 0.11 13.1 0.1 0.26 11.8 0.1 1.6 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein ELO PF01151.18 RUS76900.1 - 3.1e-51 174.3 20.9 4.1e-37 128.1 14.4 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family DUF4299 PF14132.6 RUS76900.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) RRM_1 PF00076.22 RUS76901.1 - 3.4e-07 30.0 0.0 8.1e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.30 RUS76902.1 - 1.3e-16 60.7 0.0 4.8e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 C2 domain RBD-FIP PF09457.10 RUS76902.1 - 1.7e-07 31.0 0.6 3.3e-07 30.1 0.6 1.4 1 0 0 1 1 1 1 FIP domain NblA PF04485.12 RUS76902.1 - 0.18 12.3 0.9 0.42 11.0 0.9 1.6 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Pex14_N PF04695.13 RUS76902.1 - 0.6 10.8 0.0 0.6 10.8 0.0 4.0 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region JmjC PF02373.22 RUS76904.1 - 9.3e-25 87.3 0.0 2.2e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RUS76904.1 - 4.6e-16 59.3 0.2 1.5e-15 57.7 0.2 1.8 1 0 0 1 1 1 1 Cupin-like domain QVR PF17064.5 RUS76906.1 - 4.5e-07 30.0 5.6 4.5e-07 30.0 5.6 1.8 2 1 0 2 2 2 1 Sleepless protein UL2 PF08196.11 RUS76907.1 - 0.11 12.5 0.1 17 5.5 0.0 2.6 2 0 0 2 2 2 0 UL2 protein DPPIV_N PF00930.21 RUS76908.1 - 0.00055 18.8 8.6 0.16 10.7 0.0 2.9 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4028 PF13220.6 RUS76908.1 - 0.021 14.6 7.4 27 4.6 0.1 5.3 2 1 4 6 6 6 0 Protein of unknown function (DUF4028) VHL PF01847.16 RUS76908.1 - 0.023 14.6 13.4 20 5.2 0.7 6.2 1 1 6 8 8 8 0 VHL beta domain Candida_ALS PF05792.13 RUS76908.1 - 0.037 14.6 25.5 7.4 7.2 0.1 7.7 3 3 2 5 5 5 0 Candida agglutinin-like (ALS) EAGR_box PF16713.5 RUS76908.1 - 0.076 12.7 15.7 12 5.7 0.3 6.4 2 2 6 8 8 8 0 Enriched in aromatic and glycine Residues box NPL4 PF05021.15 RUS76908.1 - 1.9 7.8 9.6 7.5 5.8 2.3 4.2 1 1 3 4 4 4 0 NPL4 family Ank_4 PF13637.6 RUS76910.1 - 4.3e-24 84.6 7.7 1e-08 35.5 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS76910.1 - 4.4e-24 84.9 0.1 3.3e-11 43.6 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS76910.1 - 1.2e-20 72.9 2.7 0.0014 19.0 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 RUS76910.1 - 4.3e-18 63.5 1.5 0.00047 20.4 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS76910.1 - 8.9e-14 51.4 4.0 0.00064 20.0 0.1 5.1 2 1 4 6 6 6 4 Ankyrin repeats (many copies) RT_RNaseH_2 PF17919.1 RUS76911.1 - 2.4e-16 59.6 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS76911.1 - 9e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 RUS76912.1 - 2.5e-16 59.2 0.1 3.6e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS76912.1 - 0.003 17.4 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 RUS76912.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Radial_spoke PF04712.12 RUS76913.1 - 3.8e-15 55.8 0.8 1.6e-07 30.7 0.0 2.7 1 1 1 2 2 2 2 Radial spokehead-like protein NUDIX PF00293.28 RUS76914.1 - 0.0015 18.6 0.1 0.0088 16.1 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain TBCC PF07986.12 RUS76915.1 - 1.8e-44 150.3 1.3 3.3e-44 149.5 1.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 RUS76915.1 - 5.2e-24 84.9 11.3 1.1e-23 83.9 11.3 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF2387 PF09526.10 RUS76915.1 - 0.11 12.6 4.7 5 7.4 0.2 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) DUF919 PF06034.11 RUS76915.1 - 1.1 9.2 9.0 0.077 12.8 2.9 2.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Spectrin PF00435.21 RUS76916.1 - 1.7e-107 353.0 167.7 3.1e-14 53.3 9.9 18.7 17 1 1 18 18 18 17 Spectrin repeat KASH PF10541.9 RUS76916.1 - 6.9e-22 77.5 5.2 1.4e-21 76.5 5.2 1.6 1 0 0 1 1 1 1 Nuclear envelope localisation domain DUF148 PF02520.17 RUS76916.1 - 0.0086 16.2 0.3 0.0086 16.2 0.3 8.0 11 1 1 12 12 12 1 Domain of unknown function DUF148 Rimk_N PF18030.1 RUS76916.1 - 0.043 14.2 0.9 0.44 11.0 0.2 2.9 2 0 0 2 2 2 0 RimK PreATP-grasp domain PMEI PF04043.15 RUS76916.1 - 5.9 7.2 6.9 12 6.2 0.4 4.2 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Spectrin PF00435.21 RUS76917.1 - 2e-33 115.0 125.3 2.2e-06 28.1 0.8 17.5 15 3 2 18 18 18 10 Spectrin repeat MKT1_C PF12246.8 RUS76917.1 - 0.025 13.8 0.8 1.5 8.0 0.1 2.9 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Baculo_PEP_C PF04513.12 RUS76917.1 - 0.15 12.1 53.7 0.68 10.0 0.0 12.6 9 3 3 13 13 13 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bcr-Abl_Oligo PF09036.10 RUS76917.1 - 9.2 6.3 9.1 7 6.7 0.2 5.2 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Spectrin PF00435.21 RUS76922.1 - 8.7e-07 29.4 11.6 3.2e-06 27.6 4.2 2.4 2 1 0 2 2 2 1 Spectrin repeat HXXSHH PF07586.11 RUS76922.1 - 0.0078 15.8 6.6 0.021 14.4 6.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1552) Vir_act_alpha_C PF10400.9 RUS76922.1 - 0.052 14.2 7.7 3.8 8.3 0.0 3.5 2 1 1 3 3 3 0 Virulence activator alpha C-term Baculo_PEP_C PF04513.12 RUS76922.1 - 0.083 12.9 3.6 1.9 8.5 0.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4600 PF15372.6 RUS76922.1 - 0.093 13.2 9.6 0.022 15.2 5.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) Elf1 PF05129.13 RUS76922.1 - 0.13 12.3 0.2 0.89 9.6 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF948 PF06103.11 RUS76922.1 - 0.16 12.3 2.8 4.2 7.7 0.1 2.7 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FliT PF05400.13 RUS76922.1 - 0.43 11.4 9.9 0.23 12.3 6.7 2.2 1 1 2 3 3 3 0 Flagellar protein FliT CREPT PF16566.5 RUS76922.1 - 0.56 10.4 8.1 2.7 8.1 6.0 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MitMem_reg PF13012.6 RUS76922.1 - 0.57 10.6 3.9 0.86 10.1 0.5 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FAM184 PF15665.5 RUS76922.1 - 0.64 9.8 10.9 2.4 7.9 9.3 1.9 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PilO PF04350.13 RUS76922.1 - 0.78 9.9 6.3 0.5 10.5 1.8 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO APG6_N PF17675.1 RUS76922.1 - 0.89 10.1 12.5 0.46 11.0 4.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 RUS76922.1 - 1.3 9.1 7.1 0.71 9.9 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS76922.1 - 1.9 7.3 11.3 3.2 6.5 10.2 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 RUS76922.1 - 2.5 7.4 5.9 8.8 5.5 0.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Rx_N PF18052.1 RUS76922.1 - 3 8.2 12.0 1.4 9.2 2.3 3.0 2 1 2 4 4 4 0 Rx N-terminal domain UPF0242 PF06785.11 RUS76922.1 - 5 7.2 13.2 14 5.8 1.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prenyltrans PF00432.21 RUS76924.1 - 2.6e-37 126.2 5.8 3.1e-14 52.4 0.0 3.1 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RUS76924.1 - 0.068 12.3 0.0 0.45 9.6 0.0 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain VWC PF00093.18 RUS76926.1 - 1.9e-07 31.3 16.0 1.9e-07 31.3 16.0 4.1 2 1 1 3 3 3 1 von Willebrand factor type C domain Cys_knot PF00007.22 RUS76926.1 - 0.00012 22.3 16.4 0.00012 22.3 16.4 3.5 1 1 2 3 3 3 1 Cystine-knot domain NARP1 PF12569.8 RUS76926.1 - 1.9 7.3 16.9 2.6 6.8 16.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ABC_membrane PF00664.23 RUS76928.1 - 3.5e-70 236.8 22.2 3.5e-40 138.4 2.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS76928.1 - 3.2e-49 167.0 14.4 2.4e-29 102.6 0.0 4.1 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 RUS76928.1 - 1.5e-11 44.2 0.0 2.6e-05 23.8 0.0 4.5 3 2 1 4 4 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RUS76928.1 - 3.1e-06 27.2 0.1 0.003 17.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS76928.1 - 4.7e-06 26.7 0.8 0.13 12.4 0.2 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 RUS76928.1 - 4.9e-05 23.2 4.3 0.0082 15.9 0.7 3.0 3 0 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 RUS76928.1 - 0.0011 18.1 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 RUS76928.1 - 0.0011 18.6 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 RUS76928.1 - 0.0094 15.5 0.1 0.63 9.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 RUS76928.1 - 0.01 15.6 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1647 PF07801.11 RUS76928.1 - 0.011 15.5 0.0 0.038 13.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) AAA_16 PF13191.6 RUS76928.1 - 0.011 16.1 0.0 0.011 16.1 0.0 4.4 4 1 0 4 4 3 0 AAA ATPase domain IstB_IS21 PF01695.17 RUS76928.1 - 0.013 15.2 0.8 8.2 6.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 RUS76928.1 - 0.024 14.2 0.1 5.6 6.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RUS76928.1 - 0.03 14.7 0.2 0.6 10.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 RUS76928.1 - 0.75 9.5 7.5 7.8 6.2 0.0 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RUS76928.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.9 4 1 0 4 4 2 0 AAA domain MeaB PF03308.16 RUS76928.1 - 6.2 5.7 11.3 1.1 8.1 0.0 2.8 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB COesterase PF00135.28 RUS76929.1 - 5.5e-81 273.0 0.0 6.7e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS76929.1 - 3e-12 46.8 0.0 6.8e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS76929.1 - 0.04 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS76929.1 - 0.05 12.4 0.0 3.3 6.5 0.1 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase COesterase PF00135.28 RUS76930.1 - 4.4e-17 62.1 0.0 4.6e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family WAP PF00095.21 RUS76931.1 - 1.3e-10 41.5 14.1 1.3e-10 41.5 14.1 2.5 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Syja_N PF02383.18 RUS76932.1 - 1.9e-74 250.9 1.2 1.9e-74 250.9 1.2 1.7 2 0 0 2 2 2 1 SacI homology domain WYL PF13280.6 RUS76932.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 WYL domain PIH1 PF08190.12 RUS76933.1 - 6.9e-37 126.5 0.2 6.9e-37 126.5 0.2 1.5 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RUS76933.1 - 4e-15 56.0 0.0 8.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain Aldedh PF00171.22 RUS76934.1 - 1.8e-156 521.3 0.0 2e-113 379.3 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 RUS76934.1 - 1.6e-05 24.4 0.1 8.6e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF1298 PF06974.13 RUS76936.1 - 1.9e-26 92.8 0.0 3.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 RUS76936.1 - 3.4e-12 46.7 0.0 9.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 RUS76936.1 - 0.052 12.2 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Condensation domain RWD PF05773.22 RUS76937.1 - 7.1e-06 26.3 4.3 0.00012 22.4 0.1 2.7 3 0 0 3 3 3 1 RWD domain zf-rbx1 PF12678.7 RUS76937.1 - 0.00096 19.4 5.4 0.0035 17.6 4.5 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS76937.1 - 0.0013 18.6 4.5 0.0035 17.2 3.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 RUS76937.1 - 0.0084 16.3 0.8 0.031 14.4 0.8 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 RUS76937.1 - 0.022 15.1 5.9 0.022 15.1 5.9 2.9 3 1 1 4 4 2 0 Ring finger domain Prok-RING_4 PF14447.6 RUS76937.1 - 0.082 12.8 5.7 4 7.4 0.3 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS76937.1 - 0.13 12.3 4.2 0.13 12.3 1.0 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 RUS76937.1 - 0.24 11.4 7.1 0.67 10.0 5.3 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 RUS76937.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.5 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 RUS76937.1 - 0.4 10.8 4.5 0.22 11.6 1.6 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RUS76937.1 - 0.53 10.2 4.3 3.3 7.6 2.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS76937.1 - 4.3 7.6 8.0 0.22 11.7 1.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Shisa PF13908.6 RUS76938.1 - 0.00037 20.8 0.3 0.0014 19.0 0.2 2.1 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator ORC6 PF05460.13 RUS76938.1 - 0.0045 16.3 0.1 0.0045 16.3 0.1 2.3 1 1 0 2 2 1 1 Origin recognition complex subunit 6 (ORC6) TMEM154 PF15102.6 RUS76938.1 - 0.0053 16.7 0.4 0.0053 16.7 0.4 2.0 2 0 0 2 2 2 1 TMEM154 protein family Podoplanin PF05808.11 RUS76938.1 - 0.012 15.7 1.6 0.018 15.1 0.2 2.0 2 0 0 2 2 2 0 Podoplanin Comm PF15957.5 RUS76938.1 - 0.025 14.9 0.0 0.071 13.5 0.0 1.8 1 0 0 1 1 1 0 Commissureless DUF4366 PF14283.6 RUS76938.1 - 0.044 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 RUS76938.1 - 0.11 11.9 0.4 0.23 10.8 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 RUS76938.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) HemY_N PF07219.13 RUS76938.1 - 0.15 12.2 0.4 0.35 11.1 0.4 1.5 1 0 0 1 1 1 0 HemY protein N-terminus MGC-24 PF05283.11 RUS76938.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.5 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4834 PF16118.5 RUS76938.1 - 0.59 11.1 0.0 0.59 11.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SelR PF01641.18 RUS76939.1 - 2.6e-48 163.1 0.2 3.6e-48 162.7 0.2 1.2 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 RUS76939.1 - 0.041 14.1 0.4 0.096 12.9 0.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 RUS76939.1 - 0.045 13.5 2.1 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ArfGap PF01412.18 RUS76941.1 - 3.5e-26 91.6 0.0 5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Med30 PF11315.8 RUS76942.1 - 1.5e-43 148.5 4.1 1.8e-43 148.3 4.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Sigma70_ner PF04546.13 RUS76942.1 - 0.00014 21.9 0.1 0.00019 21.4 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF5340 PF17275.2 RUS76942.1 - 0.45 10.7 3.3 0.64 10.2 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Ank_2 PF12796.7 RUS76943.1 - 2.3e-33 114.6 2.7 2.5e-13 50.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RUS76943.1 - 1.6e-30 104.2 5.5 1.2e-07 31.9 0.2 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 RUS76943.1 - 4.8e-30 100.2 3.6 5.5e-05 23.2 0.1 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 RUS76943.1 - 2.7e-28 97.6 9.5 9.4e-10 38.6 0.4 6.2 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS76943.1 - 3.6e-27 94.4 3.0 2.1e-09 37.7 0.0 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Pro-rich PF15240.6 RUS76943.1 - 2.1 8.6 35.6 0.075 13.3 27.7 2.1 2 0 0 2 2 2 0 Proline-rich Methyltransf_12 PF08242.12 RUS76945.1 - 0.099 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WSC PF01822.19 RUS76946.1 - 1.1e-10 41.6 3.3 3.5e-05 23.9 0.4 2.8 2 1 0 2 2 2 2 WSC domain DUF3173 PF11372.8 RUS76946.1 - 0.038 13.9 0.1 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Lysis_col PF02402.16 RUS76946.1 - 0.15 11.8 0.3 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Lysis protein VWA PF00092.28 RUS76947.1 - 5.8e-16 59.2 0.0 7.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 RUS76947.1 - 2.9e-06 27.5 8.1 2.9e-06 27.5 8.1 3.2 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.7 RUS76947.1 - 5.4e-05 23.7 5.5 5.4e-05 23.7 5.5 3.8 5 0 0 5 5 5 1 Human growth factor-like EGF ShK PF01549.24 RUS76947.1 - 0.0082 16.7 3.5 0.0082 16.7 3.5 4.4 5 0 0 5 5 5 2 ShK domain-like Hep_core_N PF08290.11 RUS76947.1 - 9.5 6.3 7.4 0.41 10.7 0.7 2.3 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger Glyco_hydro_31 PF01055.26 RUS76948.1 - 3.3e-122 408.9 1.9 4.2e-122 408.5 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RUS76948.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 RUS76948.1 - 1.5e-08 34.4 5.6 4.2e-08 32.9 5.6 1.9 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 RUS76948.1 - 0.011 16.0 0.8 0.16 12.3 0.0 3.2 3 1 1 4 4 4 0 Galactose mutarotase-like Antimicrobial_5 PF08026.11 RUS76948.1 - 1 9.5 5.0 1.7 8.8 0.1 3.0 3 0 0 3 3 3 0 Bee antimicrobial peptide DUF2909 PF11137.8 RUS76949.1 - 0.02 14.8 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) 7tm_1 PF00001.21 RUS76950.1 - 0.0018 17.6 17.1 0.0018 17.6 17.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS76950.1 - 0.91 9.5 18.3 0.84 9.6 0.7 2.7 2 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF5345 PF17280.2 RUS76951.1 - 0.031 14.3 10.2 1.5 8.9 1.7 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF4349 PF14257.6 RUS76951.1 - 0.035 13.5 0.3 9.6 5.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) WH1 PF00568.23 RUS76951.1 - 0.074 13.0 4.5 5.8 6.9 0.5 2.6 2 0 0 2 2 2 0 WH1 domain Vps23_core PF09454.10 RUS76951.1 - 2.2 8.3 4.2 36 4.4 0.2 2.8 3 0 0 3 3 3 0 Vps23 core domain P4Ha_N PF08336.11 RUS76951.1 - 3.5 7.6 7.0 45 4.0 1.0 3.3 2 2 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Helicase_IV_N PF12462.8 RUS76951.1 - 8.9 6.2 15.2 6.8 6.6 0.9 3.4 3 0 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal Acetyltransf_1 PF00583.25 RUS76952.1 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS76952.1 - 1.5e-06 28.5 0.0 2.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS76952.1 - 1.2e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS76952.1 - 0.00085 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Choline_transpo PF04515.12 RUS76954.1 - 4.5e-95 318.6 27.8 4.5e-95 318.6 27.8 2.0 2 0 0 2 2 2 2 Plasma-membrane choline transporter Sulfatase PF00884.23 RUS76955.1 - 5.8e-62 209.9 0.0 1.4e-61 208.6 0.0 1.6 1 1 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 RUS76955.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 RUS76955.1 - 0.078 12.6 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Jnk-SapK_ap_N PF09744.9 RUS76956.1 - 0.45 10.7 13.2 0.13 12.5 5.4 3.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 RUS76956.1 - 1 9.6 8.1 1.9 8.7 0.7 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4164 PF13747.6 RUS76956.1 - 2.3 8.6 11.2 0.76 10.1 5.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 RUS76956.1 - 4.2 6.2 14.0 4.6 6.0 12.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 RUS76956.1 - 4.3 6.5 8.8 2.5 7.3 6.7 1.6 1 1 1 2 2 2 0 TMPIT-like protein Hamartin PF04388.12 RUS76957.1 - 3.6e-105 353.2 1.3 4.4e-105 353.0 1.3 1.0 1 0 0 1 1 1 1 Hamartin protein OmdA PF13376.6 RUS76957.1 - 0.21 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Glyco_transf_25 PF01755.17 RUS76958.1 - 8.4e-33 113.9 2.3 1.1e-31 110.3 0.0 3.2 3 1 0 3 3 3 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 RUS76958.1 - 4e-13 49.7 0.5 1.5e-12 47.9 0.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.14 RUS76958.1 - 9.8e-09 35.0 0.4 1.6e-08 34.3 0.4 1.3 1 0 0 1 1 1 1 Anp1 CAP59_mtransfer PF11735.8 RUS76958.1 - 0.028 14.1 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Glycos_transf_2 PF00535.26 RUS76958.1 - 0.039 13.8 0.0 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RUS76958.1 - 0.14 11.6 0.1 0.35 10.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_38N PF01074.22 RUS76959.1 - 1.8e-54 185.1 3.0 2.7e-54 184.5 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS76959.1 - 2e-39 135.9 0.0 4.7e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RUS76959.1 - 1.4e-21 76.4 0.3 3.2e-21 75.3 0.3 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 RUS76959.1 - 2.4e-07 30.8 0.0 8.1e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7tm_1 PF00001.21 RUS76960.1 - 3.6e-08 33.1 10.0 5.8e-08 32.4 10.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS76960.1 - 3.8e-05 23.5 14.8 3.8e-05 23.5 14.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pex2_Pex12 PF04757.14 RUS76960.1 - 0.0013 18.3 2.2 0.0068 16.0 2.2 2.1 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region Peptidase_M56 PF05569.11 RUS76960.1 - 0.061 12.5 1.9 0.092 11.9 0.7 1.9 2 0 0 2 2 2 0 BlaR1 peptidase M56 EOS1 PF12326.8 RUS76960.1 - 0.28 11.1 3.8 0.66 9.9 3.8 1.6 1 0 0 1 1 1 0 N-glycosylation protein DUF1943 PF09172.11 RUS76962.1 - 0.12 11.6 1.2 0.16 11.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cu_amine_oxid PF01179.20 RUS76964.1 - 2.6e-74 250.6 0.2 3.1e-74 250.3 0.2 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 RUS76965.1 - 4.4e-15 55.5 0.0 6.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 RUS76965.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Trimer_CC PF08954.11 RUS76967.1 - 0.034 13.7 0.5 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Trimerisation motif SieB PF14163.6 RUS76967.1 - 0.09 12.3 0.5 18 4.8 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B LRR19-TM PF15176.6 RUS76967.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Tetraspanin PF00335.20 RUS76968.1 - 1.9e-49 168.5 6.2 2.2e-49 168.3 6.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3176 PF11374.8 RUS76968.1 - 2.7 8.2 7.6 1.2 9.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Kinesin PF00225.23 RUS76969.1 - 8.2e-87 291.2 0.1 9.8e-87 291.0 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS76969.1 - 8e-22 77.8 0.2 1.3e-21 77.1 0.2 1.4 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RUS76969.1 - 0.016 14.4 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 RUS76969.1 - 0.08 12.5 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RUS76969.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SurA_N_3 PF13624.6 RUS76970.1 - 2.5 7.9 4.9 3.7 7.3 4.0 1.6 2 0 0 2 2 2 0 SurA N-terminal domain Isochorismatase PF00857.20 RUS76972.1 - 2e-33 116.0 0.2 3.3e-33 115.3 0.2 1.3 1 1 0 1 1 1 1 Isochorismatase family Ac81 PF05820.11 RUS76972.1 - 0.079 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 Ion_trans PF00520.31 RUS76973.1 - 5.3e-33 114.3 16.0 8.1e-33 113.7 16.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS76973.1 - 9e-11 41.6 2.3 9e-11 41.6 2.3 2.6 2 1 0 2 2 2 1 Ion channel BTB_2 PF02214.22 RUS76973.1 - 0.00074 19.8 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 RUS76973.1 - 0.001 17.8 1.7 0.0017 17.1 1.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel AGH PF17558.2 RUS76973.1 - 0.34 11.1 2.3 0.5 10.5 1.1 1.9 2 0 0 2 2 2 0 Androgenic gland hormone Trp_oprn_chp PF09534.10 RUS76973.1 - 0.41 10.4 1.5 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SecE PF00584.20 RUS76973.1 - 0.57 10.2 5.8 5.4 7.0 3.1 2.8 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex CENP-B_dimeris PF09026.10 RUS76973.1 - 3.4 8.1 8.5 15 6.0 8.5 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Frag1 PF10277.9 RUS76974.1 - 2.2e-26 92.8 11.7 5.1e-26 91.6 11.7 1.5 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family PI-PLC-X PF00388.19 RUS76976.1 - 6.9e-19 67.9 0.1 1.5e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_1 PF00036.32 RUS76976.1 - 8.7e-10 37.4 4.2 6.2e-07 28.5 0.5 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RUS76976.1 - 1.1e-09 38.5 3.2 4.2e-09 36.7 0.8 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_10 PF14788.6 RUS76976.1 - 2.4e-09 36.9 0.2 7.5e-09 35.3 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS76976.1 - 2.4e-09 36.4 2.2 3.9e-06 26.3 0.5 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_like PF09279.11 RUS76976.1 - 7e-08 32.8 1.5 0.0015 19.0 0.4 3.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_5 PF13202.6 RUS76976.1 - 6.4e-06 25.4 6.6 0.0001 21.7 0.9 3.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RUS76976.1 - 0.0012 18.6 8.2 0.056 13.3 0.4 4.2 3 2 1 4 4 4 2 EF-hand domain pair MetOD2 PF18548.1 RUS76976.1 - 0.037 14.1 0.1 10 6.3 0.0 2.5 1 1 1 2 2 2 0 Metanogen output domain 2 DHO_dh PF01180.21 RUS76978.1 - 1.3e-103 346.3 0.0 1.5e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 RUS76978.1 - 0.045 12.8 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase ECH_1 PF00378.20 RUS76979.1 - 1e-22 80.7 0.0 1.3e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS76979.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NblA PF04485.12 RUS76979.1 - 0.08 13.4 0.3 0.2 12.1 0.1 1.8 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA BCNT PF07572.12 RUS76980.1 - 7.1e-27 93.3 1.2 7.1e-27 93.3 1.2 2.5 2 1 0 2 2 2 1 Bucentaur or craniofacial development Ndc1_Nup PF09531.10 RUS76980.1 - 6.9 5.2 9.2 8.3 5.0 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_permease_2 PF13520.6 RUS76981.1 - 2.1e-13 49.9 23.7 2.6e-13 49.6 23.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS76981.1 - 3.1e-07 29.4 18.6 4e-07 29.0 18.6 1.2 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 RUS76982.1 - 1.7e-80 270.7 0.0 2.1e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS76982.1 - 1.2e-14 55.0 0.0 2.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2-oxogl_dehyd_N PF16078.5 RUS76982.1 - 0.033 13.8 0.3 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus Rad4 PF03835.15 RUS76983.1 - 4.7e-24 84.7 0.6 4.7e-24 84.7 0.6 4.5 4 1 1 5 5 5 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 RUS76983.1 - 7.6e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 RUS76983.1 - 5e-19 67.9 0.0 1.7e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 RUS76983.1 - 6.5e-16 59.0 1.5 6.5e-16 59.0 1.5 6.1 5 3 0 5 5 5 1 Rad4 beta-hairpin domain 2 RNase_H PF00075.24 RUS76984.1 - 4.7e-13 49.5 0.9 7.9e-13 48.8 0.9 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS76984.1 - 0.0017 18.1 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like HATPase_c_5 PF14501.6 RUS76984.1 - 0.018 15.0 6.0 0.17 11.8 3.9 2.7 1 1 0 2 2 2 0 GHKL domain Pga1 PF10333.9 RUS76984.1 - 0.11 12.4 0.8 0.18 11.7 0.8 1.3 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator fn3 PF00041.21 RUS76985.1 - 2.4e-18 66.2 6.5 0.00052 20.3 0.3 5.2 4 1 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 RUS76985.1 - 0.02 15.1 0.6 0.067 13.4 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin V-set domain I-set PF07679.16 RUS76985.1 - 0.024 14.7 0.1 0.07 13.2 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS76986.1 - 5.9e-66 219.0 4.9 1.4e-12 48.0 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 RUS76986.1 - 5e-59 196.4 0.0 1.5e-13 50.6 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS76986.1 - 2e-55 185.0 12.9 7.4e-10 39.0 0.2 7.6 8 0 0 8 8 8 6 Immunoglobulin domain ig PF00047.25 RUS76986.1 - 1.4e-40 137.3 3.0 2.8e-06 27.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 RUS76986.1 - 7.1e-24 84.1 12.9 0.014 15.5 0.2 9.1 6 4 1 7 7 7 7 Immunoglobulin V-set domain fn3 PF00041.21 RUS76986.1 - 1.6e-17 63.6 10.6 0.0011 19.3 0.0 5.7 5 1 0 5 5 5 4 Fibronectin type III domain Ig_5 PF16681.5 RUS76986.1 - 9.9e-14 51.5 0.0 0.0022 18.4 0.0 6.2 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS76986.1 - 3.8e-12 45.6 0.0 0.47 10.1 0.0 6.0 6 0 0 6 6 6 4 Immunoglobulin domain Ig_4 PF16680.5 RUS76986.1 - 1.6e-08 34.7 0.3 0.59 10.4 0.0 6.5 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS76986.1 - 1.7e-08 34.4 0.1 0.35 11.0 0.0 5.2 5 0 0 5 5 4 3 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 RUS76986.1 - 1.9e-06 27.9 1.0 1.4 9.0 0.1 5.1 5 0 0 5 5 5 1 CD47 immunoglobulin-like domain UL45 PF05473.12 RUS76986.1 - 3.9e-05 23.4 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 RUS76986.1 - 7.4e-05 23.4 0.0 0.00027 21.7 0.0 2.0 1 0 0 1 1 1 1 Lectin C-type domain Ig_C17orf99 PF17736.1 RUS76986.1 - 0.0001 22.2 0.0 4.9 7.3 0.0 5.3 5 0 0 5 5 5 1 C17orf99 Ig domain C2-set PF05790.15 RUS76986.1 - 0.045 13.9 0.0 7.6 6.8 0.0 4.2 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 RUS76986.1 - 0.3 10.9 1.6 6.9 6.5 0.0 3.5 4 0 0 4 4 3 0 Adenovirus E3 region protein CR1 BTV_NS2 PF04514.12 RUS76988.1 - 0.048 12.5 0.9 0.07 12.0 0.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 fn3_6 PF17766.1 RUS76988.1 - 0.055 13.6 1.9 10 6.4 1.9 3.0 1 1 0 1 1 1 0 Fibronectin type-III domain RUN PF02759.19 RUS76990.1 - 2.8e-18 66.2 0.0 6.4e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 RUN domain TPR_MLP1_2 PF07926.12 RUS76990.1 - 0.0027 17.8 4.9 0.0055 16.8 4.9 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 RUS76990.1 - 0.004 16.4 4.8 0.0066 15.7 4.8 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein BTV_NS2 PF04514.12 RUS76990.1 - 0.13 11.1 0.9 0.23 10.2 0.9 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 JIP_LZII PF16471.5 RUS76990.1 - 0.37 11.0 2.7 3.2 8.0 0.5 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Golgin_A5 PF09787.9 RUS76990.1 - 0.72 9.3 10.2 1.1 8.7 10.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.15 RUS76990.1 - 5.2 6.9 7.6 7 6.5 0.3 2.7 1 1 2 3 3 3 0 Septum formation initiator HIP1_clath_bdg PF16515.5 RUS76990.1 - 8 7.2 10.6 2 9.1 5.3 2.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 RUS76991.1 - 6.8e-29 101.0 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS76991.1 - 1.1e-22 80.5 0.0 4.9e-22 78.4 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS76991.1 - 0.00047 19.6 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Homeodomain PF00046.29 RUS76992.1 - 1.1e-22 79.6 8.5 1.8e-22 78.9 7.8 1.7 2 0 0 2 2 2 1 Homeodomain QLQ PF08880.11 RUS76992.1 - 0.00064 19.4 0.5 0.00064 19.4 0.5 1.7 2 0 0 2 2 2 1 QLQ RE_MamI PF09567.10 RUS76992.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 MamI restriction endonuclease Herpes_BLLF1 PF05109.13 RUS76993.1 - 0.0018 16.4 41.8 0.0022 16.1 41.8 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) ASC PF00858.24 RUS76994.1 - 5.7e-45 154.1 2.3 6.5e-44 150.6 2.3 2.1 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Lectin_C PF00059.21 RUS76995.1 - 1.4e-37 128.7 9.5 4.4e-18 66.0 1.0 4.5 4 0 0 4 4 4 4 Lectin C-type domain ShK PF01549.24 RUS76995.1 - 5.6e-09 36.4 21.5 1.5e-07 31.8 5.9 3.2 2 0 0 2 2 2 2 ShK domain-like UL45 PF05473.12 RUS76995.1 - 1.2e-07 31.5 12.8 0.61 9.7 0.3 4.9 4 2 0 4 4 4 4 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 RUS76995.1 - 4.9e-06 25.9 0.3 0.065 12.5 0.0 3.2 3 1 1 4 4 4 2 Chordopoxvirus A33R protein Podoplanin PF05808.11 RUS76995.1 - 0.0027 17.8 0.4 0.0048 17.0 0.4 1.3 1 0 0 1 1 1 1 Podoplanin TM_helix PF05552.12 RUS76996.1 - 0.11 12.4 0.4 0.11 12.4 0.4 7.2 2 2 4 6 6 6 0 Conserved TM helix zf-H2C2_2 PF13465.6 RUS76997.1 - 3.6e-07 30.3 16.8 1.8e-06 28.1 6.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS76997.1 - 2.3e-06 27.7 16.7 0.0027 18.1 4.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 RUS76997.1 - 0.00037 20.8 8.0 0.0049 17.2 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS76997.1 - 0.00054 20.6 14.9 0.046 14.6 3.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS76997.1 - 0.0016 18.7 9.1 0.012 15.9 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Big_11 PF18200.1 RUS76997.1 - 0.006 16.5 2.2 0.0094 15.8 0.1 2.3 2 1 0 2 2 2 1 Bacterial Ig-like domain zf-C2H2_6 PF13912.6 RUS76997.1 - 0.75 9.9 13.8 0.42 10.7 3.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PSK_trans_fac PF07704.11 RUS76997.1 - 3.4 8.5 7.3 7.8 7.3 6.9 1.8 1 1 0 1 1 1 0 Rv0623-like transcription factor Elf1 PF05129.13 RUS76997.1 - 6.5 6.9 10.8 21 5.2 1.5 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 RUS76997.1 - 8.6 6.6 10.9 6.8 6.9 2.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger MRP-S31 PF15433.6 RUS76998.1 - 3.6e-71 240.5 3.4 4.2e-71 240.2 3.4 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 ATE_C PF04377.15 RUS76999.1 - 0.1 13.2 0.1 0.12 13.0 0.1 1.1 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus GMC_oxred_N PF00732.19 RUS77000.1 - 3.2e-82 276.2 0.0 4e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RUS77000.1 - 2.7e-41 141.4 0.0 4.7e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 RUS77000.1 - 2.4e-05 24.1 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS77000.1 - 0.00026 20.3 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RUS77000.1 - 0.0007 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 RUS77000.1 - 0.0011 19.2 0.1 0.0031 17.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS77000.1 - 0.005 16.0 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 RUS77000.1 - 0.016 14.0 0.1 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 RUS77000.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 RUS77000.1 - 0.13 11.5 0.0 8.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 RUS77000.1 - 0.18 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ANTH PF07651.16 RUS77001.1 - 5e-77 258.6 0.1 6.3e-77 258.3 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 RUS77001.1 - 1.5e-12 47.6 0.3 3.3e-12 46.6 0.1 1.6 2 0 0 2 2 2 1 ENTH domain Profilin PF00235.19 RUS77004.1 - 1.3e-34 119.2 0.0 1.6e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Profilin TACI-CRD2 PF09305.10 RUS77004.1 - 0.17 11.9 2.1 4.9 7.3 0.1 2.4 2 0 0 2 2 2 0 TACI, cysteine-rich domain GST_C_2 PF13410.6 RUS77005.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS77005.1 - 0.025 14.8 0.0 0.12 12.7 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_17 PF13431.6 RUS77006.1 - 1.1e-05 25.5 3.2 0.0012 19.0 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.10 RUS77006.1 - 0.0045 16.0 1.7 0.0053 15.8 0.5 1.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.6 RUS77006.1 - 0.012 15.2 2.0 0.032 13.9 2.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 RUS77006.1 - 0.014 15.4 3.6 0.32 11.2 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS77006.1 - 0.031 14.8 7.0 0.06 13.9 1.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS77006.1 - 0.088 13.5 0.2 0.79 10.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS77006.1 - 0.38 11.7 2.5 14 6.9 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS77006.1 - 0.86 9.5 5.2 1.8 8.5 2.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PAE PF03283.13 RUS77007.1 - 0.067 12.3 0.2 0.074 12.2 0.2 1.1 1 0 0 1 1 1 0 Pectinacetylesterase HLH PF00010.26 RUS77008.1 - 8.9e-15 54.4 0.6 1.7e-14 53.5 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAD_binding_7 PF03441.14 RUS77009.1 - 5.3e-77 257.9 1.0 7.5e-77 257.4 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RUS77009.1 - 2.6e-43 147.9 0.0 5.7e-43 146.7 0.0 1.5 2 0 0 2 2 2 1 DNA photolyase DeoC PF01791.9 RUS77012.1 - 4.1e-27 95.3 0.0 5e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase HU-CCDC81_euk_2 PF18289.1 RUS77013.1 - 8.6e-24 83.5 0.0 3.8e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 RUS77013.1 - 1.1e-23 83.1 1.3 2e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 Bac_DNA_binding PF00216.21 RUS77013.1 - 3e-06 27.3 0.1 0.013 15.7 0.0 2.9 2 0 0 2 2 2 2 Bacterial DNA-binding protein HU-HIG PF18291.1 RUS77013.1 - 0.00056 20.0 0.1 0.024 14.7 0.0 2.8 2 0 0 2 2 2 1 HU domain fused to wHTH, Ig, or Glycine-rich motif CBM_14 PF01607.24 RUS77013.1 - 0.065 13.4 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain TSC22 PF01166.18 RUS77014.1 - 7.4e-07 29.4 1.2 1.2e-06 28.8 1.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family ZapB PF06005.12 RUS77014.1 - 2.2e-05 24.8 2.0 4.9e-05 23.7 2.0 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 RUS77014.1 - 8.1e-05 22.3 1.0 0.00013 21.7 1.0 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 RUS77014.1 - 0.00017 21.6 1.2 0.00043 20.3 1.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 RUS77014.1 - 0.00064 19.6 1.1 0.00075 19.4 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 RUS77014.1 - 0.00098 19.7 2.6 0.0051 17.4 2.0 2.0 1 1 1 2 2 2 1 SlyX Cnn_1N PF07989.11 RUS77014.1 - 0.0015 18.6 1.8 0.0027 17.8 1.8 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 RUS77014.1 - 0.007 16.6 3.0 0.033 14.4 2.0 1.8 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 RUS77014.1 - 0.012 15.0 3.4 0.015 14.7 3.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2381 PF09544.10 RUS77014.1 - 0.014 15.0 0.3 0.015 14.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) V_ATPase_I PF01496.19 RUS77014.1 - 0.028 12.4 0.4 0.032 12.2 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.18 RUS77014.1 - 0.039 14.2 4.8 0.11 12.7 4.8 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper BLOC1_2 PF10046.9 RUS77014.1 - 0.043 14.1 2.8 0.12 12.6 1.9 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 RUS77014.1 - 0.049 14.3 2.4 0.073 13.7 1.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 RUS77014.1 - 0.055 13.6 3.2 0.092 12.8 3.2 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF2730 PF10805.8 RUS77014.1 - 0.069 13.3 0.6 0.099 12.7 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Bap31_Bap29_C PF18035.1 RUS77014.1 - 0.088 12.8 1.8 0.29 11.2 1.8 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Shugoshin_N PF07558.11 RUS77014.1 - 0.094 12.6 2.8 0.17 11.8 2.8 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.12 RUS77014.1 - 0.14 12.2 0.4 0.17 11.9 0.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 RUS77014.1 - 0.18 12.3 6.1 0.12 12.9 3.5 1.9 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Chibby PF14645.6 RUS77014.1 - 0.23 11.9 2.5 0.32 11.4 2.3 1.3 1 1 0 1 1 1 0 Chibby family JIP_LZII PF16471.5 RUS77014.1 - 0.25 11.5 5.3 0.61 10.3 5.2 1.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 RUS77014.1 - 0.29 11.7 7.2 0.52 10.8 7.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 RUS77014.1 - 0.29 11.6 2.2 0.36 11.3 2.2 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DHR10 PF18595.1 RUS77014.1 - 0.3 11.2 8.2 0.11 12.5 5.2 1.7 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain bZIP_2 PF07716.15 RUS77014.1 - 0.35 11.0 6.5 1.3 9.2 6.5 1.9 1 1 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 RUS77014.1 - 0.5 10.5 6.3 0.61 10.2 4.7 2.0 2 1 1 3 3 2 0 Sperm tail C-terminal domain Nnf1 PF03980.14 RUS77014.1 - 0.5 10.8 6.1 0.96 9.9 6.1 1.7 1 1 0 1 1 1 0 Nnf1 Prefoldin_2 PF01920.20 RUS77014.1 - 0.5 10.3 6.8 0.44 10.5 5.2 1.7 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 RUS77014.1 - 0.55 10.7 3.4 0.39 11.1 1.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 RUS77015.1 - 8.5e-32 109.6 1.0 1.2e-31 109.2 0.4 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 RUS77015.1 - 0.0018 18.2 1.4 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Prefoldin subunit End3 PF12761.7 RUS77015.1 - 0.007 16.6 2.2 0.045 13.9 0.1 2.1 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 BST2 PF16716.5 RUS77015.1 - 0.08 13.5 0.9 5.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 zf-AN1 PF01428.16 RUS77017.1 - 7.5 6.8 11.7 1.4e+02 2.8 0.4 4.7 1 1 4 6 6 6 0 AN1-like Zinc finger I-set PF07679.16 RUS77018.1 - 2.8e-37 126.7 0.1 1.4e-20 73.1 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77018.1 - 1.5e-22 80.0 8.6 3.2e-11 43.7 0.0 4.6 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RUS77018.1 - 5.8e-12 45.8 0.7 7.7e-06 26.2 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS77018.1 - 6.4e-12 45.5 0.0 4.7e-06 26.7 0.0 3.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS77018.1 - 8e-05 22.8 8.4 0.061 13.5 0.0 4.7 3 1 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS77018.1 - 0.0007 19.6 0.0 2.8 8.1 0.0 3.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Acyl_transf_1 PF00698.21 RUS77019.1 - 1.1e-76 258.4 0.1 1.8e-76 257.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 RUS77019.1 - 3.3e-55 187.4 0.3 6.5e-55 186.5 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 RUS77019.1 - 1.3e-41 142.5 0.0 2.7e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 RUS77019.1 - 3.5e-35 120.6 0.0 7.6e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 RUS77019.1 - 5.3e-33 113.8 0.1 1.7e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 RUS77019.1 - 2.5e-16 59.8 0.1 2.3e-15 56.6 0.1 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 RUS77019.1 - 6.8e-08 32.2 0.1 5.6e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 RUS77019.1 - 9.4e-06 25.6 0.0 0.00073 19.5 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS77019.1 - 1.9e-05 25.7 0.0 7e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VP4_helical PF17478.2 RUS77020.1 - 1.3 8.4 11.4 1.3 8.4 3.8 3.2 1 1 1 2 2 2 0 Rotavirus VP4 helical domain Pentapeptide_4 PF13599.6 RUS77020.1 - 2.7 8.2 35.8 31 4.8 17.3 3.2 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Rho_Binding PF08912.11 RUS77020.1 - 3 8.7 8.6 1.4 9.8 2.4 2.6 1 1 1 2 2 2 0 Rho Binding Guanylate_cyc PF00211.20 RUS77021.1 - 1.3e-28 99.9 0.6 5.5e-26 91.3 0.3 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS77021.1 - 1.2e-12 47.7 1.6 1.3e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Heme NO binding associated DUF2457 PF10446.9 RUS77021.1 - 1.2 8.3 19.5 1.8 7.6 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS77021.1 - 3.2 5.9 19.9 4.3 5.4 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS77021.1 - 3.9 5.7 12.1 5.4 5.2 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TUDOR PF00567.24 RUS77022.1 - 4.7e-51 171.9 0.0 4.1e-20 72.0 0.0 3.8 4 0 0 4 4 4 3 Tudor domain DUF3483 PF11982.8 RUS77023.1 - 1.2 8.7 7.8 0.052 13.2 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) Fasciclin PF02469.22 RUS77026.1 - 8e-07 29.3 0.1 9.3e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain CpxA_peri PF16527.5 RUS77026.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.3 1 1 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain FGE-sulfatase PF03781.16 RUS77027.1 - 1.1e-54 185.8 0.9 1.4e-54 185.4 0.9 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 GPR15L PF15854.5 RUS77027.1 - 0.15 12.3 0.4 0.32 11.3 0.4 1.5 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 DUF1980 PF09323.10 RUS77027.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) HNH_3 PF13392.6 RUS77028.1 - 0.36 10.6 3.2 16 5.3 0.0 3.2 3 0 0 3 3 3 0 HNH endonuclease EGF_3 PF12947.7 RUS77029.1 - 2.5e-09 37.2 17.4 9.9e-06 25.7 3.5 2.5 2 0 0 2 2 2 2 EGF domain Fasciclin PF02469.22 RUS77029.1 - 0.00011 22.4 0.5 0.04 14.1 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3377 PF11857.8 RUS77029.1 - 0.008 16.1 0.4 0.015 15.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Amnionless PF14828.6 RUS77029.1 - 0.02 13.8 0.2 0.027 13.3 0.2 1.1 1 0 0 1 1 1 0 Amnionless m04gp34like PF12216.8 RUS77029.1 - 0.02 14.5 0.2 0.03 13.9 0.2 1.2 1 0 0 1 1 1 0 Immune evasion protein DAG1 PF05454.11 RUS77029.1 - 0.053 12.9 0.3 0.074 12.4 0.3 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) HCMV_UL124 PF17609.2 RUS77029.1 - 0.082 13.1 0.6 0.15 12.3 0.2 1.6 2 0 0 2 2 1 0 Family of unknown function Mid2 PF04478.12 RUS77029.1 - 0.09 12.6 3.0 0.15 11.9 3.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 RUS77029.1 - 0.18 11.7 2.4 0.33 10.9 2.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 RUS77029.1 - 0.2 12.4 1.1 0.5 11.2 1.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal cEGF PF12662.7 RUS77029.1 - 0.23 11.4 9.7 0.58 10.1 1.6 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like RANK_CRD_2 PF18278.1 RUS77029.1 - 0.27 11.4 8.1 0.31 11.2 4.1 2.5 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 ASFV_J13L PF05568.11 RUS77029.1 - 0.29 10.9 2.5 0.47 10.2 2.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Insulin_TMD PF17870.1 RUS77029.1 - 0.31 11.2 3.4 0.58 10.3 3.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF_MSP1_1 PF12946.7 RUS77029.1 - 0.35 11.0 10.1 0.24 11.5 0.7 2.8 2 1 0 2 2 2 0 MSP1 EGF domain 1 Fasciclin PF02469.22 RUS77030.1 - 2.3e-13 50.5 0.0 3.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain FAM199X PF15814.5 RUS77030.1 - 0.068 12.2 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X EGF_2 PF07974.13 RUS77032.1 - 0.04 14.3 14.4 0.04 14.3 14.4 5.2 5 1 0 5 5 5 0 EGF-like domain 7tm_1 PF00001.21 RUS77033.1 - 2.3e-26 92.7 20.1 2.7e-26 92.5 20.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS77033.1 - 5.2e-11 42.4 24.5 4.3e-10 39.4 24.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS77033.1 - 0.00028 20.6 16.0 0.00028 20.6 16.0 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS77033.1 - 0.082 12.6 16.4 0.12 12.1 16.4 1.3 1 1 0 1 1 1 0 Olfactory receptor Viral_cys_rich PF08008.12 RUS77035.1 - 8.2e-05 22.6 5.5 0.4 10.8 0.2 3.1 1 1 2 3 3 3 3 Viral cysteine rich FF PF01846.19 RUS77035.1 - 0.0016 18.6 0.1 2.5 8.3 0.0 3.6 2 1 2 4 4 4 1 FF domain RHH_7 PF16777.5 RUS77035.1 - 0.0023 18.2 4.3 2.1 8.8 0.4 3.4 1 1 2 3 3 3 2 Transcriptional regulator, RHH-like, CopG MbtH PF03621.13 RUS77035.1 - 0.0068 15.8 0.9 36 3.9 0.0 5.0 1 1 7 8 8 8 0 MbtH-like protein Prot_ATP_ID_OB PF16450.5 RUS77035.1 - 0.023 14.7 2.2 69 3.5 0.1 4.7 1 1 6 7 7 7 0 Proteasomal ATPase OB C-terminal domain Linocin_M18 PF04454.12 RUS77035.1 - 0.06 12.6 1.2 2.3 7.5 0.1 2.7 1 1 2 3 3 3 0 Encapsulating protein for peroxidase MULE PF10551.9 RUS77035.1 - 0.066 13.6 0.7 11 6.6 0.1 2.3 1 1 1 2 2 2 0 MULE transposase domain FAM47 PF14642.6 RUS77035.1 - 0.078 12.5 0.1 1.6 8.2 0.0 1.9 1 1 1 2 2 2 0 FAM47 family CLTH PF10607.9 RUS77035.1 - 0.12 12.2 2.1 0.27 11.1 2.1 1.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain HSR PF03172.13 RUS77035.1 - 0.14 12.3 7.2 1.6 8.9 1.2 2.8 1 1 2 3 3 3 0 HSR domain STI1 PF17830.1 RUS77035.1 - 0.26 11.2 5.2 68 3.5 0.1 4.6 3 2 2 5 5 5 0 STI1 domain Fasciclin PF02469.22 RUS77036.1 - 2.9e-38 131.0 0.4 8.5e-18 64.8 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain EGF_3 PF12947.7 RUS77036.1 - 6e-08 32.8 24.0 4.4e-06 26.8 8.9 6.7 6 0 0 6 6 6 3 EGF domain EGF_2 PF07974.13 RUS77036.1 - 0.0028 18.0 14.1 0.0028 18.0 14.1 7.0 5 2 1 6 6 6 3 EGF-like domain FXa_inhibition PF14670.6 RUS77036.1 - 0.0094 16.2 10.7 0.0094 16.2 10.7 7.0 4 2 1 5 5 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS77036.1 - 0.55 10.2 43.5 1.2 9.2 2.7 6.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like SSF PF00474.17 RUS77037.1 - 7.5e-35 120.6 25.7 9.8e-35 120.2 25.7 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family 7tm_1 PF00001.21 RUS77038.1 - 6.6e-56 189.6 11.8 8.7e-56 189.1 11.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS77038.1 - 1.8e-07 30.8 23.3 1.7e-06 27.6 23.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS77038.1 - 5.1e-07 29.6 11.0 5.1e-07 29.6 11.0 2.8 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS77038.1 - 5.1e-06 26.1 21.6 0.00015 21.2 21.2 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RUS77038.1 - 0.00045 20.0 7.5 0.00045 20.0 7.5 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.21 RUS77039.1 - 1.5e-21 76.9 0.2 1.7e-21 76.7 0.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS77039.1 - 1.6e-05 24.4 0.4 2.1e-05 24.1 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS77039.1 - 2.6e-05 24.0 0.3 3.2e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS77039.1 - 0.056 13.2 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Olfactory receptor Steroid_dh PF02544.16 RUS77040.1 - 1.2e-21 77.2 3.9 1.6e-21 76.9 3.9 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 RUS77040.1 - 0.0029 17.2 0.3 0.0036 16.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 RUS77040.1 - 0.0058 17.0 1.4 0.0073 16.7 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase PSD4 PF07631.11 RUS77041.1 - 0.61 10.6 2.0 1.7 9.2 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) PSI_PsaJ PF01701.18 RUS77042.1 - 0.48 11.0 10.9 2.9 8.5 0.7 2.8 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Acetyltransf_8 PF13523.6 RUS77042.1 - 1.6 8.4 3.1 19 4.9 0.1 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Hydin_ADK PF17213.3 RUS77045.1 - 0.095 13.0 0.5 0.095 13.0 0.5 2.5 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Caldesmon PF02029.15 RUS77045.1 - 2.1 7.0 18.0 3.2 6.4 18.0 1.2 1 1 0 1 1 1 0 Caldesmon FAM60A PF15396.6 RUS77045.1 - 6.5 6.7 17.7 21 5.0 16.0 2.0 2 0 0 2 2 2 0 Protein Family FAM60A NDT80_PhoG PF05224.12 RUS77046.1 - 3.2e-25 89.4 0.9 8.1e-24 84.9 0.9 2.3 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 RUS77046.1 - 3.1e-18 64.6 0.6 5.6e-18 63.8 0.6 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 MRF_C2 PF13888.6 RUS77046.1 - 5.7e-13 48.9 0.8 1.3e-12 47.8 0.8 1.6 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 Peptidase_S74 PF13884.6 RUS77046.1 - 7.1e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase EphA2_TM PF14575.6 RUS77046.1 - 0.0055 17.6 1.5 0.92 10.4 1.3 3.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 RUS77046.1 - 0.038 12.7 0.2 0.038 12.7 0.2 2.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) Tmemb_9 PF05434.11 RUS77046.1 - 0.042 13.7 2.8 0.42 10.5 3.0 2.4 2 0 0 2 2 2 0 TMEM9 DUF4834 PF16118.5 RUS77046.1 - 1.1 10.2 12.8 0.45 11.5 3.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 RUS77046.1 - 1.7 9.0 16.5 11 6.4 11.7 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF929 PF06053.11 RUS77046.1 - 6.1 6.1 9.3 9.4 5.5 7.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF929) Orf78 PF06024.12 RUS77046.1 - 7.7 6.9 9.8 0.73 10.2 2.9 2.7 2 1 0 2 2 2 0 Orf78 (ac78) zf-met PF12874.7 RUS77047.1 - 5.8e-35 118.7 46.7 6.4e-05 23.2 0.7 8.7 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS77047.1 - 1.3e-15 57.2 53.2 9.2e-05 22.6 0.2 8.8 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS77047.1 - 1.1e-12 48.1 30.7 0.099 13.0 0.0 8.3 6 1 2 8 8 8 6 C2H2 type zinc-finger (2 copies) DEAD PF00270.29 RUS77047.1 - 2.1e-11 43.9 0.0 4.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RUS77047.1 - 2.1e-10 40.9 0.0 5.2e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3449 PF11931.8 RUS77047.1 - 0.002 17.9 9.9 0.012 15.4 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3449) SWI2_SNF2 PF18766.1 RUS77047.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Rad50_zn_hook PF04423.14 RUS77047.1 - 0.91 9.4 3.0 15 5.5 0.0 3.5 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-MYST PF17772.1 RUS77047.1 - 3.3 7.4 14.7 20 4.9 0.0 5.0 5 0 0 5 5 5 0 MYST family zinc finger domain zf-C2H2_4 PF13894.6 RUS77047.1 - 4.8 8.3 32.3 9.6 7.3 0.1 8.2 8 0 0 8 8 8 0 C2H2-type zinc finger DSPc PF00782.20 RUS77048.1 - 2.9e-59 198.7 0.1 3.7e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS77048.1 - 2.3e-09 37.2 0.3 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RUS77048.1 - 0.012 15.8 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 RUS77048.1 - 0.098 13.0 0.0 7.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Rit1 DUSP-like domain DSPn PF14671.6 RUS77048.1 - 0.11 13.0 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Astacin PF01400.24 RUS77049.1 - 1.1e-64 217.6 0.7 2e-64 216.8 0.7 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 RUS77049.1 - 3.2e-10 40.4 26.5 3.3e-05 24.3 12.2 2.7 2 0 0 2 2 2 2 ShK domain-like Peptidase_M10 PF00413.24 RUS77049.1 - 0.00049 20.0 0.4 0.042 13.7 0.2 2.4 2 0 0 2 2 2 1 Matrixin Peptidase_M66 PF10462.9 RUS77049.1 - 0.0007 18.6 0.1 0.0007 18.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase M66 Peptidase_M57 PF12388.8 RUS77049.1 - 0.064 12.9 0.5 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 RUS77049.1 - 0.078 13.5 0.2 0.23 12.0 0.2 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like BPL_N PF09825.9 RUS77050.1 - 1.1e-60 205.7 0.1 1.4e-60 205.4 0.1 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.14 RUS77050.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 RUS77050.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Med19 PF10278.9 RUS77051.1 - 0.25 11.2 4.4 2.7 7.9 3.5 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PHD PF00628.29 RUS77053.1 - 3.1e-10 39.8 8.5 3.1e-10 39.8 8.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 RUS77053.1 - 3.1e-08 33.8 5.4 3.1e-08 33.8 5.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RUS77053.1 - 6.5e-06 25.9 5.7 6.5e-06 25.9 5.7 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS77053.1 - 2.4e-05 24.1 5.5 2.4e-05 24.1 5.5 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS77053.1 - 2.6e-05 24.1 6.0 2.6e-05 24.1 6.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS77053.1 - 0.00062 19.6 2.3 0.00062 19.6 2.3 3.1 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS77053.1 - 0.00076 19.4 3.3 0.00076 19.4 3.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS77053.1 - 0.00097 19.0 6.3 0.00097 19.0 6.3 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS77053.1 - 0.0038 17.5 6.6 0.0038 17.5 6.6 3.2 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RUS77053.1 - 0.031 14.4 9.7 0.021 15.0 5.8 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING C1_2 PF03107.16 RUS77053.1 - 0.16 12.3 4.1 0.58 10.5 4.1 2.0 1 0 0 1 1 1 0 C1 domain Zn_ribbon_17 PF17120.5 RUS77053.1 - 0.89 9.2 12.4 2.9 7.6 4.5 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 RUS77053.1 - 3.8 7.6 12.0 0.3 11.2 1.7 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Clat_adaptor_s PF01217.20 RUS77054.1 - 5.4e-57 191.7 1.5 6.3e-57 191.5 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 RUS77054.1 - 0.0018 16.9 0.3 0.0022 16.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Acetyltransf_19 PF18015.1 RUS77054.1 - 0.067 13.4 0.3 0.099 12.9 0.3 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 RUS77055.1 - 9.9e-43 146.4 0.0 1.1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77055.1 - 4.4e-22 78.6 0.0 4.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 RUS77055.1 - 5.2e-05 23.0 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 RUS77055.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RUS77055.1 - 0.07 13.0 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNase_H PF00075.24 RUS77056.1 - 2.2e-10 40.9 1.7 8.6e-10 39.0 0.1 2.4 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS77056.1 - 0.00048 19.9 0.1 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like DUF4864 PF16156.5 RUS77056.1 - 0.076 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) LPMO_10 PF03067.15 RUS77057.1 - 5.7e-12 46.7 0.1 4.3e-10 40.6 0.0 2.4 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading Dus PF01207.17 RUS77058.1 - 4e-16 59.0 0.1 3.2e-15 56.0 0.1 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) SmpA_OmlA PF04355.13 RUS77060.1 - 0.053 13.3 13.5 15 5.5 0.1 7.2 4 1 3 8 8 8 0 SmpA / OmlA family DUF4708 PF15813.5 RUS77061.1 - 1.6e-82 276.8 0.0 2.1e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) HeH PF12949.7 RUS77061.1 - 0.00024 20.7 0.1 0.00061 19.4 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain DUF3106 PF11304.8 RUS77061.1 - 0.00067 20.1 2.0 0.051 14.0 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3106) TPR_7 PF13176.6 RUS77062.1 - 0.14 12.2 0.1 0.52 10.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT PF02985.22 RUS77062.1 - 0.91 10.0 6.7 42 4.8 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 RUS77062.1 - 5.4 7.2 11.8 1.1 9.4 0.2 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RRM_1 PF00076.22 RUS77063.1 - 4.8e-11 42.3 0.0 8.8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF629 PF04780.12 RUS77063.1 - 0.046 12.3 4.7 0.024 13.2 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF629) Limkain-b1 PF11608.8 RUS77063.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 zf-C2H2 PF00096.26 RUS77063.1 - 0.55 10.8 7.4 1.6 9.4 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 RUS77063.1 - 2.5 8.0 4.0 33 4.4 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 RUS77063.1 - 5.8 8.0 8.2 5.8 8.0 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS77063.1 - 9.1 6.1 7.3 31 4.4 2.5 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Vps35 PF03635.17 RUS77064.1 - 1.5e-295 982.5 4.3 1.7e-295 982.3 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MOR2-PAG1_N PF14222.6 RUS77064.1 - 3.7e-05 22.9 0.0 0.022 13.7 0.0 2.5 2 1 0 2 2 2 2 Cell morphogenesis N-terminal TRF PF08558.10 RUS77064.1 - 0.0073 15.9 2.1 6.7 6.2 0.0 3.3 3 0 0 3 3 3 2 Telomere repeat binding factor (TRF) DUF1804 PF08822.11 RUS77064.1 - 0.011 15.7 0.0 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) RecJ_OB PF17768.1 RUS77064.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 RecJ OB domain COX4 PF02936.14 RUS77065.1 - 1.3e-50 171.0 0.3 1.5e-50 170.8 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF2890 PF11081.8 RUS77065.1 - 0.0036 17.4 0.7 0.0051 16.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) eIF-6 PF01912.18 RUS77066.1 - 6.5e-79 263.9 1.1 9.9e-79 263.3 0.6 1.5 1 1 1 2 2 2 1 eIF-6 family PT PF04886.12 RUS77068.1 - 8.3e-12 44.5 3.1 0.67 9.5 0.0 7.3 5 4 1 6 6 6 5 PT repeat Nop14 PF04147.12 RUS77069.1 - 3.7e-07 28.8 31.9 5.2e-07 28.3 31.9 1.3 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 RUS77069.1 - 8.7e-07 27.5 25.6 8.7e-07 27.5 25.6 3.0 2 1 0 2 2 1 1 DNA polymerase phi Folate_carrier PF01770.18 RUS77069.1 - 0.00032 19.6 6.9 0.62 8.7 10.5 2.1 2 0 0 2 2 2 2 Reduced folate carrier V_ATPase_I PF01496.19 RUS77069.1 - 0.00076 17.5 1.5 0.00076 17.5 1.5 2.0 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Pex24p PF06398.11 RUS77069.1 - 0.0064 15.5 2.1 2 7.3 0.0 2.1 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin CBP_BcsG PF11658.8 RUS77069.1 - 0.04 12.3 3.2 0.93 7.8 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG SARAF PF06682.12 RUS77069.1 - 0.041 13.5 1.7 12 5.5 0.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Wzy_C PF04932.15 RUS77069.1 - 0.092 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase RNA_pol_Rpc4 PF05132.14 RUS77069.1 - 0.11 13.0 20.5 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 PHO4 PF01384.20 RUS77069.1 - 0.17 10.9 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family SR-25 PF10500.9 RUS77069.1 - 0.23 11.0 37.6 0.34 10.5 37.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 RUS77069.1 - 0.27 11.4 16.6 1.4 9.1 10.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 RUS77069.1 - 1.4 7.3 15.0 8.9 4.6 15.0 1.9 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 RUS77069.1 - 4 6.5 16.5 0.34 10.1 0.0 2.1 1 1 0 2 2 2 0 ZIP Zinc transporter DUF3405 PF11885.8 RUS77069.1 - 4.6 5.7 11.3 6.1 5.3 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) CCSAP PF15748.5 RUS77070.1 - 0.28 11.3 46.5 0.51 10.5 46.5 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hamartin PF04388.12 RUS77070.1 - 3 6.4 23.7 2.9 6.5 23.7 1.1 1 0 0 1 1 1 0 Hamartin protein zf-C2H2 PF00096.26 RUS77071.1 - 9.6e-22 76.2 23.6 0.00019 21.7 0.2 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77071.1 - 7.4e-15 54.4 24.4 0.0035 18.0 0.2 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS77071.1 - 1.5e-13 50.5 27.4 8.8e-09 35.4 0.2 6.9 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS77071.1 - 2.7e-06 27.5 10.2 0.29 11.5 0.0 5.4 6 0 0 6 6 5 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RUS77071.1 - 3.1e-06 26.9 7.3 0.006 16.5 0.1 3.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 RUS77071.1 - 4.7e-06 26.5 25.1 0.0036 17.3 1.1 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS77071.1 - 4.6e-05 23.7 11.8 1.1 9.7 0.1 4.5 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 RUS77071.1 - 0.00011 22.5 6.4 0.0059 16.9 0.7 3.4 3 1 1 4 4 4 2 C2H2-type zinc ribbon Evr1_Alr PF04777.13 RUS77071.1 - 0.00023 21.6 10.4 0.62 10.6 0.2 4.3 4 0 0 4 4 4 1 Erv1 / Alr family zf-MYST PF17772.1 RUS77071.1 - 0.00026 20.5 1.7 6.3 6.5 0.0 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 RUS77071.1 - 0.00055 19.6 0.1 0.00055 19.6 0.1 4.2 5 0 0 5 5 4 1 zinc-finger C2H2-type zf-met PF12874.7 RUS77071.1 - 0.0007 19.9 12.4 1.1 9.7 0.1 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RUS77071.1 - 0.00094 18.7 4.5 2.4 7.8 0.1 4.2 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 RUS77071.1 - 0.0032 17.4 4.3 3.1 7.9 0.2 4.0 4 0 0 4 4 3 1 Adenylate kinase, active site lid zf-C2HE PF16278.5 RUS77071.1 - 0.0061 17.0 10.7 1.2 9.7 0.2 4.7 4 1 0 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 RUS77071.1 - 0.011 15.6 7.8 2.5 8.1 0.2 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_aberr PF17017.5 RUS77071.1 - 0.015 15.5 8.8 0.43 10.7 3.2 3.8 2 1 2 4 4 4 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 RUS77071.1 - 0.024 14.4 8.3 0.029 14.1 0.0 3.7 4 0 0 4 4 3 0 C2H2-type zinc-finger domain BAP PF06639.11 RUS77071.1 - 0.073 13.4 4.3 1.2 9.5 0.0 3.5 3 1 0 3 3 3 0 Basal layer antifungal peptide (BAP) Zn-ribbon_8 PF09723.10 RUS77071.1 - 0.084 13.0 11.8 17 5.7 0.4 4.7 5 0 0 5 5 4 0 Zinc ribbon domain Ta0938 PF11494.8 RUS77071.1 - 0.14 12.4 4.2 4.4 7.6 0.0 3.7 3 1 0 4 4 4 0 Ta0938 TFIIS_C PF01096.18 RUS77071.1 - 0.74 9.7 0.0 0.74 9.7 0.0 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-AN1 PF01428.16 RUS77071.1 - 0.83 9.9 13.2 7.2 6.9 0.2 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger LIM PF00412.22 RUS77071.1 - 0.95 9.7 12.6 1.4 9.2 0.1 4.1 4 0 0 4 4 4 0 LIM domain IBR PF01485.21 RUS77071.1 - 1.2 9.4 6.9 4 7.7 0.1 3.8 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain zf-C2H2_3rep PF18868.1 RUS77071.1 - 1.8 9.2 19.9 3.9 8.2 0.2 4.6 2 2 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 RUS77071.1 - 2 9.1 7.9 36 5.1 0.1 4.5 4 1 0 4 4 4 0 FOXP coiled-coil domain zf-trcl PF13451.6 RUS77071.1 - 3.3 7.7 8.6 8.2 6.4 0.2 3.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 RUS77071.1 - 6.1 7.7 17.5 8.9 7.1 1.1 5.1 3 2 1 4 4 4 0 zinc-ribbon family RAWUL PF16207.5 RUS77072.1 - 1.1e-19 70.8 0.0 2.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 RUS77072.1 - 3.2e-16 58.9 11.0 5.3e-16 58.2 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS77072.1 - 8.3e-10 38.4 11.5 1.4e-09 37.7 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS77072.1 - 2.7e-09 37.2 9.3 4.5e-09 36.5 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS77072.1 - 5e-08 32.7 8.6 7.4e-08 32.1 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS77072.1 - 3.1e-06 27.1 8.8 6.6e-06 26.0 8.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS77072.1 - 1.1e-05 25.3 9.6 1.8e-05 24.6 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RUS77072.1 - 2.4e-05 24.4 8.5 4.8e-05 23.4 8.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 RUS77072.1 - 0.0001 22.0 6.1 0.00019 21.2 6.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RUS77072.1 - 0.00061 19.5 7.0 0.0013 18.5 7.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 RUS77072.1 - 0.0014 18.5 3.4 0.0029 17.4 3.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RUS77072.1 - 0.0026 18.0 7.8 0.0068 16.7 7.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 RUS77072.1 - 0.014 15.5 2.3 0.044 13.9 2.3 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 RUS77072.1 - 0.064 13.2 7.8 0.24 11.3 7.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS77072.1 - 0.067 13.1 9.0 0.78 9.6 9.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 RUS77072.1 - 0.32 11.2 7.1 1.1 9.5 7.4 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 RUS77072.1 - 0.49 10.2 5.0 1.1 9.0 5.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C4_Topoisom PF01396.19 RUS77072.1 - 2.4 8.0 5.2 0.28 11.0 0.9 1.7 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger DZR PF12773.7 RUS77072.1 - 5.6 7.1 7.7 64 3.7 7.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon STELLO PF03385.17 RUS77073.1 - 6.1e-34 117.5 6.9 1e-24 87.1 0.0 2.3 2 0 0 2 2 2 2 STELLO glycosyltransferases End3 PF12761.7 RUS77075.1 - 1.4 9.0 8.8 0.079 13.1 3.0 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 CytochromB561_N PF09786.9 RUS77076.1 - 8.7e-34 117.5 0.5 9.5e-34 117.3 0.5 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal Laminin_II PF06009.12 RUS77077.1 - 0.26 11.3 14.6 0.52 10.3 2.1 2.8 2 1 0 2 2 2 0 Laminin Domain II YtxH PF12732.7 RUS77077.1 - 0.33 11.5 1.8 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 YtxH-like protein CENP-H PF05837.12 RUS77077.1 - 4.7 7.7 20.1 0.39 11.2 0.5 4.2 3 1 0 3 3 3 0 Centromere protein H (CENP-H) ACOX PF01756.19 RUS77078.1 - 3.1e-44 150.7 0.1 6.7e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RUS77078.1 - 9.2e-30 103.8 0.1 1.9e-29 102.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RUS77078.1 - 2e-11 43.9 0.0 3.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RUS77078.1 - 0.0044 17.2 0.0 0.023 14.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS77078.1 - 0.0064 17.1 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain TPR_12 PF13424.6 RUS77079.1 - 1.6e-40 137.2 26.8 1.4e-14 54.1 0.7 4.8 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 RUS77079.1 - 2.5e-22 77.7 28.4 8.8e-05 22.2 0.0 8.2 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 RUS77079.1 - 1.2e-20 72.7 18.4 5.9e-05 22.8 1.2 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77079.1 - 1.5e-20 71.6 25.3 0.00013 21.9 0.3 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS77079.1 - 2.2e-19 68.0 23.8 0.00016 21.6 0.1 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS77079.1 - 3.5e-10 39.2 14.6 0.0058 16.6 0.5 7.7 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS77079.1 - 5e-10 39.3 4.3 0.011 15.1 0.2 3.7 2 1 1 4 4 4 4 MalT-like TPR region TPR_19 PF14559.6 RUS77079.1 - 8.8e-08 32.6 11.6 0.17 12.4 0.4 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS77079.1 - 2.9e-06 27.6 7.6 26 6.0 0.0 7.0 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS77079.1 - 1.2e-05 25.6 11.8 0.48 11.2 0.2 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS77079.1 - 0.00015 21.9 15.6 2.2 8.9 0.1 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.6 RUS77079.1 - 0.00045 19.7 9.4 0.039 13.4 1.8 3.1 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 RUS77079.1 - 0.00048 20.7 9.9 7.2 7.3 0.0 6.2 5 3 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 RUS77079.1 - 0.00049 20.2 3.9 0.0024 17.9 0.7 3.4 2 2 1 3 3 3 1 Domain of Unknown Function (DUF3856) DUF5113 PF17140.4 RUS77079.1 - 0.0033 17.2 2.2 1.6 8.5 0.3 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5113) TPR_9 PF13371.6 RUS77079.1 - 0.0049 17.0 5.6 12 6.1 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77079.1 - 0.0072 16.0 12.4 0.52 10.0 0.0 6.4 7 0 0 7 7 7 1 TPR repeat Rapsyn_N PF10579.9 RUS77079.1 - 0.027 14.6 0.5 17 5.6 0.1 3.4 2 2 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region RPN7 PF10602.9 RUS77079.1 - 0.055 13.2 7.0 1.1 8.9 0.2 3.7 2 1 2 4 4 4 0 26S proteasome subunit RPN7 SPOB_a PF14689.6 RUS77079.1 - 0.057 13.1 2.3 23 4.8 0.0 4.2 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_4 PF07721.14 RUS77079.1 - 0.077 13.7 3.0 5.4 7.9 0.5 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DnaJ PF00226.31 RUS77079.1 - 0.14 12.3 0.3 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 DnaJ domain TPR_15 PF13429.6 RUS77079.1 - 0.2 10.9 3.4 5 6.3 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS77079.1 - 0.7 10.0 10.9 6.3 6.9 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 RUS77079.1 - 0.9 9.9 8.6 47 4.5 0.1 5.8 7 1 0 7 7 7 0 PPR repeat SPATA24 PF15175.6 RUS77080.1 - 5.6e-13 49.2 38.3 3.1e-10 40.2 31.5 2.5 1 1 1 2 2 2 2 Spermatogenesis-associated protein 24 Macoilin PF09726.9 RUS77080.1 - 0.085 11.4 25.3 0.13 10.8 25.3 1.2 1 0 0 1 1 1 0 Macoilin family AA_kinase PF00696.28 RUS77081.1 - 7.4e-41 140.3 0.0 9.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family SQHop_cyclase_C PF13243.6 RUS77082.1 - 5.9e-58 196.5 0.4 3.1e-52 177.7 1.2 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 RUS77082.1 - 4.4e-45 154.0 0.1 5.1e-38 130.8 0.0 4.5 3 1 2 5 5 5 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 RUS77082.1 - 5e-34 115.7 18.6 1.4e-09 37.5 0.1 6.1 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 RUS77082.1 - 1.4e-08 34.4 0.2 0.35 10.2 0.1 4.9 4 1 0 4 4 4 3 Pectic acid lyase CBF PF03914.17 RUS77083.1 - 2.7e-26 92.6 0.8 2.7e-26 92.6 0.8 1.7 2 0 0 2 2 2 1 CBF/Mak21 family Coat_F PF07875.12 RUS77083.1 - 0.039 14.2 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Coat F domain LURAP PF14854.6 RUS77084.1 - 1.3e-06 28.3 1.8 1.3e-06 28.3 1.8 2.6 2 1 1 3 3 3 1 Leucine rich adaptor protein AMP-binding PF00501.28 RUS77085.1 - 2.2e-35 122.1 0.0 2.4e-34 118.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DUF1375 PF07119.12 RUS77085.1 - 0.13 12.6 0.1 0.47 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) CAP_GLY PF01302.25 RUS77086.1 - 1.3e-70 233.4 7.6 4.5e-24 84.2 0.4 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.7 RUS77086.1 - 3.8e-12 46.6 0.4 1.4e-10 41.6 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS77086.1 - 1.1e-10 41.4 4.5 0.01 16.3 0.6 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RUS77086.1 - 1.4e-09 38.3 1.7 8.8e-06 26.2 0.3 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS77086.1 - 2.2e-08 34.2 3.5 0.002 18.4 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS77086.1 - 2.7e-08 33.4 0.9 0.067 13.8 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat SHIPPO-rpt PF07004.12 RUS77087.1 - 0.0013 19.6 43.0 0.2 12.6 3.9 7.8 9 0 0 9 9 9 4 Sperm-tail PG-rich repeat Peptidase_M20 PF01546.28 RUS77088.1 - 3.9e-33 114.9 0.0 5.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RUS77088.1 - 7.8e-17 61.2 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RUS77088.1 - 3.7e-07 30.0 0.0 2.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 RUS77088.1 - 0.095 11.7 0.0 0.58 9.1 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase 7tm_1 PF00001.21 RUS77089.1 - 1.6e-31 109.6 0.9 2.5e-31 109.0 0.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS77089.1 - 0.00021 21.2 5.1 0.00021 21.2 5.1 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF2207 PF09972.9 RUS77089.1 - 0.33 9.7 7.0 0.21 10.3 0.2 2.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SIT PF15330.6 RUS77089.1 - 0.59 10.6 3.8 27 5.2 0.2 3.1 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT CitMHS PF03600.16 RUS77089.1 - 2.8 7.1 6.0 12 5.0 5.1 2.3 2 1 0 2 2 2 0 Citrate transporter 7tm_1 PF00001.21 RUS77090.1 - 1.1e-29 103.6 2.4 1.8e-29 102.9 2.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS77090.1 - 0.00067 19.5 14.0 0.0042 16.9 6.6 2.2 2 0 0 2 2 2 2 Olfactory receptor DUF5305 PF17231.2 RUS77090.1 - 0.11 11.9 0.2 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TAS2R PF05296.13 RUS77090.1 - 2 7.5 14.0 0.2 10.7 8.3 2.2 2 1 1 3 3 3 0 Taste receptor protein (TAS2R) Glyco_hydro_20 PF00728.22 RUS77091.1 - 2.6e-89 300.1 0.0 3.3e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 RUS77091.1 - 5.1e-20 71.7 0.0 9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 RUS77091.1 - 2.9e-18 65.6 0.0 6.5e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 RUS77091.1 - 1e-12 48.9 0.0 2.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 RUS77091.1 - 0.083 13.5 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Ras PF00071.22 RUS77093.1 - 2.4e-55 186.6 0.0 2.8e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS77093.1 - 1.9e-31 108.8 0.0 2.7e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS77093.1 - 8.3e-12 44.9 0.0 9.1e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS77093.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.4 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS77093.1 - 5.8e-05 22.7 0.1 0.0078 15.8 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RUS77093.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS77093.1 - 0.0005 20.0 0.0 0.0041 17.0 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 RUS77093.1 - 0.0019 17.5 0.0 0.033 13.5 0.1 2.2 2 0 0 2 2 2 1 Septin AAA_5 PF07728.14 RUS77093.1 - 0.0031 17.5 0.0 0.0045 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS77093.1 - 0.013 15.7 0.0 0.042 14.1 0.0 1.7 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 RUS77093.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 RUS77093.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RUS77093.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.6 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 RUS77093.1 - 0.025 14.3 0.0 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RUS77093.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RUS77093.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 RUS77093.1 - 0.041 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 RUS77093.1 - 0.041 13.6 0.1 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 RUS77093.1 - 0.054 12.7 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 RUS77093.1 - 0.079 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 RUS77093.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 RUS77093.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RuvB_N PF05496.12 RUS77093.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain G-alpha PF00503.20 RUS77093.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 RUS77093.1 - 0.16 12.4 0.1 0.35 11.3 0.0 1.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Methyltransf_31 PF13847.6 RUS77094.1 - 3.8e-21 75.5 0.0 6.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS77094.1 - 4.8e-13 49.3 0.0 6.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS77094.1 - 1.5e-10 41.6 0.0 3.4e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS77094.1 - 2.2e-08 34.8 0.1 3.9e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS77094.1 - 2.6e-07 31.2 0.0 6.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 RUS77094.1 - 3.3e-06 26.9 0.0 4.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 RUS77094.1 - 3.7e-06 26.6 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RUS77094.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 RUS77094.1 - 0.00039 19.9 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 RUS77094.1 - 0.00045 19.9 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 RUS77094.1 - 0.0078 15.5 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 RUS77094.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 RUS77094.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme tRNA_U5-meth_tr PF05958.11 RUS77094.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 RUS77094.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 RUS77094.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 RUS77094.1 - 0.11 13.6 0.0 0.18 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Vg_Tdu PF07545.14 RUS77095.1 - 1.4e-05 24.8 0.5 1.6 8.6 0.0 3.6 3 0 0 3 3 3 3 Vestigial/Tondu family DUF4816 PF16086.5 RUS77096.1 - 0.52 10.3 43.1 1.8e+04 -30.3 43.1 6.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) Profilin PF00235.19 RUS77099.1 - 1.2e-27 96.7 0.0 1.4e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Dcc1 PF09724.9 RUS77100.1 - 1.6e-84 284.1 0.8 2.1e-84 283.7 0.1 1.5 2 0 0 2 2 2 1 Sister chromatid cohesion protein Dcc1 MaoC_dehydrat_N PF13452.6 RUS77100.1 - 0.041 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase DUF1192 PF06698.11 RUS77100.1 - 0.12 12.5 0.1 22 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SIX1_SD PF16878.5 RUS77101.1 - 3.9e-49 165.8 0.9 5.6e-49 165.3 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RUS77101.1 - 2.8e-14 52.7 1.6 3.9e-14 52.2 0.5 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS77101.1 - 6e-13 48.5 0.5 1.8e-12 46.9 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 RUS77101.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix Homez PF11569.8 RUS77101.1 - 0.023 14.2 0.1 0.023 14.2 0.1 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 RUS77101.1 - 0.084 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PMP22_Claudin PF00822.20 RUS77102.1 - 0.013 15.4 7.0 0.036 13.9 7.0 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CDC45 PF02724.14 RUS77103.1 - 0.054 11.8 14.4 0.072 11.4 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PMP22_Claudin PF00822.20 RUS77103.1 - 0.26 11.1 3.7 0.73 9.7 3.9 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Nop14 PF04147.12 RUS77103.1 - 0.39 8.9 21.0 0.47 8.6 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 RUS77103.1 - 0.77 9.0 30.3 1.2 8.4 30.3 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS77103.1 - 0.83 7.7 34.2 1.1 7.3 34.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RUS77103.1 - 1.2 8.2 37.3 1.6 7.8 37.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 RUS77103.1 - 2.9 7.2 20.8 3.6 6.9 20.8 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS77103.1 - 3 7.1 14.3 4.1 6.7 14.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 RUS77103.1 - 5 6.8 11.2 7.7 6.2 11.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH WD40 PF00400.32 RUS77104.1 - 4.1e-17 62.2 4.6 0.00012 22.8 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77104.1 - 4e-05 23.8 0.0 0.0087 16.3 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5576 PF17739.1 RUS77104.1 - 0.21 11.7 3.1 18 5.5 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5576) VSP PF03302.13 RUS77105.1 - 0.035 13.0 0.5 0.054 12.3 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4834 PF16118.5 RUS77105.1 - 1.3 10.1 0.0 1.3 10.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3715 PF12509.8 RUS77106.1 - 1.3e-18 67.4 0.1 1.3e-18 67.4 0.1 4.1 4 1 1 5 5 5 2 Protein of unknown function (DUF3715) PRIMA1 PF16101.5 RUS77107.1 - 3.6 7.7 6.3 0.69 10.0 1.4 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 VbhA PF18495.1 RUS77109.1 - 0.086 12.7 19.8 11 6.0 0.2 6.7 6 2 2 8 8 8 0 Antitoxin VbhA DUF2807 PF10988.8 RUS77109.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain LapA_dom PF06305.11 RUS77110.1 - 0.25 11.2 1.4 0.72 9.7 0.2 2.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Tim17 PF02466.19 RUS77111.1 - 5.3e-05 23.6 5.7 0.00026 21.4 5.7 1.9 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Pex14_N PF04695.13 RUS77112.1 - 0.35 11.5 3.8 0.54 10.9 3.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 RUS77114.1 - 2e-26 93.0 0.2 1.6e-14 53.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77114.1 - 2.5e-06 27.0 0.3 0.00081 18.7 0.4 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase LSM PF01423.22 RUS77116.1 - 2.8e-15 55.8 0.4 3.4e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 LSM domain zf-C2H2 PF00096.26 RUS77117.1 - 1.2e-72 236.5 238.1 0.00023 21.4 1.0 32.5 32 0 0 32 32 32 29 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77117.1 - 2.5e-69 223.9 242.4 0.0057 17.4 0.8 32.5 33 0 0 33 33 32 30 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS77117.1 - 1.3e-66 218.2 228.1 4.8e-06 26.8 0.1 32.7 31 3 1 32 32 32 19 Zinc-finger double domain zf-met PF12874.7 RUS77117.1 - 1.6e-28 98.2 145.3 0.00011 22.4 0.3 27.7 30 0 0 30 30 30 13 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS77117.1 - 7.8e-26 89.8 148.4 0.018 15.4 0.2 28.7 32 0 0 32 32 31 15 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS77117.1 - 1.8e-20 72.4 216.4 0.0028 17.6 1.6 32.1 33 2 0 33 33 32 19 C2H2-type zinc finger GAGA PF09237.11 RUS77117.1 - 0.0049 16.7 0.1 0.0049 16.7 0.1 11.1 10 4 3 13 13 13 1 GAGA factor Zn-ribbon_8 PF09723.10 RUS77117.1 - 0.024 14.7 0.3 0.024 14.7 0.3 20.1 15 9 9 24 24 24 0 Zinc ribbon domain zf-Di19 PF05605.12 RUS77117.1 - 0.029 14.7 159.9 0.057 13.7 3.1 18.6 6 5 17 24 24 24 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS77117.1 - 0.036 14.8 121.4 0.26 11.9 5.3 15.0 4 2 10 15 15 15 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 RUS77117.1 - 0.049 13.5 0.4 0.049 13.5 0.4 25.3 28 0 0 28 28 27 0 zinc-finger of a C2HC-type DUF3535 PF12054.8 RUS77118.1 - 7.1e-48 163.9 0.1 4.7e-45 154.6 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) HEAT PF02985.22 RUS77118.1 - 4e-15 54.6 9.1 0.079 13.3 0.0 8.7 8 1 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 RUS77118.1 - 1.7e-08 34.8 5.5 0.0012 19.1 0.8 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 RUS77118.1 - 2.2e-06 28.0 0.5 2.2e-06 28.0 0.5 5.5 6 1 2 8 8 8 1 HEAT-like repeat TAF6_C PF07571.13 RUS77118.1 - 1.9e-05 24.9 0.4 14 6.1 0.0 5.8 5 2 1 6 6 6 2 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 RUS77118.1 - 0.0015 19.1 0.0 0.0077 16.8 0.0 2.3 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 RUS77118.1 - 0.005 16.0 0.1 0.0098 15.0 0.1 1.4 1 0 0 1 1 1 1 Dopey, N-terminal Adaptin_N PF01602.20 RUS77118.1 - 0.098 11.2 0.5 2.7 6.4 0.1 2.6 2 1 1 3 3 3 0 Adaptin N terminal region Thioredoxin PF00085.20 RUS77119.1 - 2.9e-27 94.6 1.1 1e-08 35.1 0.1 4.7 4 1 1 5 5 5 3 Thioredoxin Thioredoxin_2 PF13098.6 RUS77119.1 - 1.5e-06 28.6 0.5 0.48 10.9 0.1 3.9 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RUS77119.1 - 1.4e-05 25.2 0.8 0.2 11.8 0.1 3.0 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 RUS77119.1 - 7.2e-05 22.7 0.9 0.17 11.8 0.1 2.7 1 1 1 2 2 2 2 AhpC/TSA family LigB PF02900.18 RUS77119.1 - 0.045 12.8 0.1 3.4 6.7 0.0 2.4 1 1 1 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase TraF PF13728.6 RUS77119.1 - 0.094 12.5 1.3 12 5.6 0.0 3.2 2 1 1 3 3 3 0 F plasmid transfer operon protein HEPN_MAE_28990 PF18737.1 RUS77119.1 - 0.16 11.9 0.3 24 4.7 0.1 2.4 1 1 1 2 2 2 0 MAE_28990/MAE_18760-like HEPN ATP-sulfurylase PF01747.17 RUS77120.1 - 1.5e-69 233.8 0.0 2e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 RUS77120.1 - 3.7e-48 163.2 0.0 1.5e-47 161.3 0.0 1.9 2 0 0 2 2 2 1 PUA-like domain APS_kinase PF01583.20 RUS77120.1 - 6.2e-27 94.4 0.0 1e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Methyltransf_25 PF13649.6 RUS77121.1 - 8.2e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS77121.1 - 4.1e-15 56.2 0.0 7.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS77121.1 - 2e-10 41.3 0.0 4.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS77121.1 - 2.8e-07 30.5 0.0 3.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS77121.1 - 1.4e-06 28.3 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS77121.1 - 7.1e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 RUS77121.1 - 0.00066 18.9 0.0 0.00096 18.4 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 RUS77121.1 - 0.009 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 RUS77121.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 RUS77121.1 - 0.023 13.2 0.0 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 RUS77121.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase EnY2 PF10163.9 RUS77121.1 - 1.6 9.2 3.8 2.1 8.8 0.8 2.5 2 1 0 2 2 1 0 Transcription factor e(y)2 Methyltransf_25 PF13649.6 RUS77122.1 - 6.1e-11 42.9 0.0 2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS77122.1 - 2.3e-10 41.0 0.0 5.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS77122.1 - 4.3e-10 40.2 0.0 9.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS77122.1 - 0.00051 19.9 0.0 0.0035 17.1 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS77122.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RUS77122.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RUS77122.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 RUS77122.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 RUS77122.1 - 0.042 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 RUS77122.1 - 0.05 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 RUS77122.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TUDOR PF00567.24 RUS77124.1 - 8e-19 67.9 0.0 8e-19 67.9 0.0 3.6 3 1 1 4 4 4 1 Tudor domain RRM_1 PF00076.22 RUS77124.1 - 3.1e-10 39.7 0.0 7.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 RUS77124.1 - 1e-06 28.3 0.0 1e-06 28.3 0.0 3.4 3 1 0 3 3 3 1 Protein kinase domain TFIIA PF03153.13 RUS77124.1 - 7.1e-06 26.3 38.6 7.1e-06 26.3 38.6 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Agenet PF05641.12 RUS77124.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.8 1 0 0 1 1 1 0 Agenet domain DUF853 PF05872.12 RUS77124.1 - 0.056 12.0 10.4 0.11 11.1 10.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RRM_7 PF16367.5 RUS77124.1 - 0.092 12.9 0.0 0.092 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif PAT1 PF09770.9 RUS77124.1 - 0.45 8.7 34.2 0.87 7.8 34.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 RUS77124.1 - 1.5 8.3 31.5 0.016 14.8 15.6 3.5 3 1 0 3 3 3 0 Exonuclease VII, large subunit CTP_transf_3 PF02348.19 RUS77124.1 - 8 6.3 15.6 4.4 7.2 12.9 1.9 2 0 0 2 2 2 0 Cytidylyltransferase CBM_14 PF01607.24 RUS77125.1 - 3.8e-24 84.6 11.9 1.1e-11 44.7 0.8 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Mucin PF01456.17 RUS77125.1 - 1.1e-07 32.0 21.2 1.1e-07 31.9 21.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein E_Pc_C PF06752.12 RUS77125.1 - 0.18 11.9 13.8 0.24 11.5 13.8 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus FSA_C PF10479.9 RUS77125.1 - 0.65 8.1 10.7 0.84 7.7 10.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Baculo_VP91_N PF08475.10 RUS77125.1 - 0.68 9.6 5.2 1.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Sugar_tr PF00083.24 RUS77128.1 - 2.4e-12 46.5 24.5 5.8e-11 41.9 24.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS77128.1 - 1.1e-10 41.1 40.7 5.4e-06 25.6 21.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.21 RUS77129.1 - 6.6e-29 101.2 0.3 8.3e-29 100.9 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.16 RUS77130.1 - 4.7e-09 35.6 33.5 3.2e-08 32.9 33.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3817 PF12823.7 RUS77130.1 - 2.8 8.8 7.4 4.8 8.1 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3817) Peptidase_C97 PF05903.14 RUS77131.1 - 6.4e-42 142.9 0.0 7.3e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain AIG1 PF04548.16 RUS77132.1 - 9.4e-43 146.0 0.1 9.4e-43 146.0 0.1 2.1 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS77132.1 - 4.2e-09 36.5 2.0 9.8e-09 35.3 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS77132.1 - 0.004 16.6 0.1 0.004 16.6 0.1 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 RUS77132.1 - 0.008 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ZNRF_3_ecto PF18212.1 RUS77132.1 - 0.037 14.0 1.4 0.48 10.4 0.7 2.5 2 0 0 2 2 2 0 ZNRF-3 Ectodomain DUF5616 PF18481.1 RUS77132.1 - 0.049 14.0 0.1 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) AAA_22 PF13401.6 RUS77132.1 - 0.077 13.3 0.9 0.4 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RUS77132.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS77132.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 RUS77132.1 - 0.77 10.3 0.0 0.77 10.3 0.0 3.2 2 1 0 2 2 1 0 ABC transporter Exonuc_VII_L PF02601.15 RUS77132.1 - 3 7.3 24.3 0.63 9.6 19.6 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit AAA_33 PF13671.6 RUS77132.1 - 3.4 7.8 7.5 0.33 11.1 0.5 2.9 2 2 1 3 3 3 0 AAA domain CwsA PF10814.8 RUS77132.1 - 4.4 7.5 5.3 2.8 8.1 3.2 1.8 2 0 0 2 2 1 0 Cell wall synthesis protein CwsA ALMT PF11744.8 RUS77132.1 - 5.6 5.7 12.5 8.1 5.2 12.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SCAN PF02023.17 RUS77134.1 - 2.9e-09 36.6 0.1 2.9e-09 36.6 0.1 2.1 2 0 0 2 2 2 1 SCAN domain RVT_1 PF00078.27 RUS77135.1 - 0.0019 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RUS77135.1 - 0.0078 16.2 0.0 0.087 12.9 0.0 2.1 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77136.1 - 0.053 13.0 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pro_isomerase PF00160.21 RUS77137.1 - 9.2e-47 159.2 0.0 1.1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3271 PF11675.8 RUS77137.1 - 0.035 13.4 0.0 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) AAA_33 PF13671.6 RUS77138.1 - 2.4e-06 27.8 0.0 2.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 RUS77140.1 - 5.6e-129 429.8 0.4 4.4e-127 423.6 0.0 3.5 3 1 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RUS77140.1 - 1.1e-127 427.1 9.9 1.1e-127 427.1 9.9 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RUS77140.1 - 3.7e-116 388.5 9.5 3.7e-116 388.5 9.5 5.0 3 2 1 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RUS77140.1 - 2.7e-72 242.5 0.2 2.7e-72 242.5 0.2 3.9 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 RUS77140.1 - 3.2e-67 226.6 0.0 1.6e-66 224.3 0.0 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RUS77140.1 - 1.4e-43 148.5 0.0 2.4e-36 124.9 0.0 5.2 5 0 0 5 5 5 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RUS77140.1 - 1.8e-39 135.2 0.0 4.7e-39 133.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RUS77140.1 - 2.5e-39 135.3 14.8 5.3e-39 134.2 14.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS77140.1 - 9.2e-31 106.4 0.0 1e-29 103.0 0.0 3.0 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RUS77140.1 - 1.2e-30 106.3 0.0 6.3e-13 48.9 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RUS77140.1 - 5.9e-17 61.9 0.4 3.2e-16 59.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 RUS77140.1 - 6.3e-15 55.6 2.8 0.014 15.7 0.0 6.8 7 0 0 7 7 5 4 AAA domain AAA PF00004.29 RUS77140.1 - 1.6e-13 51.3 0.0 0.018 15.5 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RUS77140.1 - 1.1e-12 48.3 0.3 0.0038 17.4 0.0 5.7 5 0 0 5 5 4 3 AAA domain Dynein_C PF18199.1 RUS77140.1 - 3.6e-12 46.1 0.0 3.6e-12 46.1 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 RUS77140.1 - 4.8e-11 43.3 0.0 0.92 9.9 0.0 6.5 4 1 1 5 5 5 3 AAA ATPase domain AAA_18 PF13238.6 RUS77140.1 - 3e-10 40.8 2.6 0.28 11.7 0.0 6.3 5 0 0 5 5 5 3 AAA domain Mg_chelatase PF01078.21 RUS77140.1 - 2.1e-07 30.6 0.1 0.62 9.4 0.0 4.9 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 RUS77140.1 - 5.9e-07 28.8 0.0 0.12 11.4 0.0 4.2 3 1 1 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.27 RUS77140.1 - 2.4e-06 28.1 1.1 0.45 11.0 0.0 5.5 4 0 0 4 4 4 2 ABC transporter AAA_29 PF13555.6 RUS77140.1 - 4e-06 26.5 0.0 0.49 10.2 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 RUS77140.1 - 1.2e-05 25.1 0.4 4.8 6.9 0.0 4.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 RUS77140.1 - 1.5e-05 24.5 0.0 0.82 9.0 0.0 3.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_19 PF13245.6 RUS77140.1 - 4.8e-05 23.7 0.4 0.26 11.6 0.0 4.8 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 RUS77140.1 - 0.0001 22.6 0.0 6.5 7.2 0.0 5.0 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 RUS77140.1 - 0.00019 21.2 0.8 0.37 10.5 0.0 5.1 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_lid_1 PF17857.1 RUS77140.1 - 0.00026 21.2 0.2 0.0074 16.5 0.0 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA_24 PF13479.6 RUS77140.1 - 0.00047 19.9 0.1 27 4.4 0.0 4.7 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 RUS77140.1 - 0.00092 19.2 0.0 8.9 6.2 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain NACHT PF05729.12 RUS77140.1 - 0.018 14.9 0.3 47 3.8 0.0 4.3 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 RUS77140.1 - 0.032 13.8 2.0 0.31 10.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain RuvB_N PF05496.12 RUS77140.1 - 0.057 13.2 0.1 0.91 9.2 0.0 2.8 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 RUS77140.1 - 0.069 13.0 0.0 22 4.7 0.0 3.5 4 0 0 4 4 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 RUS77140.1 - 0.07 13.2 6.7 27 4.7 0.0 5.4 4 0 0 4 4 4 0 Helicase HerA, central domain Xpo1 PF08389.12 RUS77141.1 - 2.4e-29 102.3 5.9 2.4e-29 102.3 5.9 3.7 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 RUS77141.1 - 5.5e-07 29.4 0.1 5.5e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 RUS77141.1 - 0.0012 19.5 0.2 0.018 15.6 0.1 3.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region RasGEF_N PF00618.20 RUS77141.1 - 0.046 13.9 0.3 14 6.0 0.0 3.3 2 0 0 2 2 2 0 RasGEF N-terminal motif DUF3510 PF12022.8 RUS77141.1 - 0.13 12.7 0.7 6.3 7.2 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) Occludin_ELL PF07303.13 RUS77141.1 - 0.15 12.8 4.6 7.9 7.3 0.1 3.4 3 0 0 3 3 3 0 Occludin homology domain CPSase_L_D2 PF02786.17 RUS77143.1 - 2e-78 262.8 0.4 3.4e-78 262.0 0.4 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 RUS77143.1 - 1.5e-68 230.4 0.2 2.7e-68 229.6 0.2 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 RUS77143.1 - 5.3e-43 146.0 0.0 1.3e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 RUS77143.1 - 7.9e-32 110.8 0.0 2.5e-30 105.9 0.0 2.6 2 0 0 2 2 2 1 HMGL-like Biotin_carb_C PF02785.19 RUS77143.1 - 4.1e-29 100.9 0.0 1.2e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RUS77143.1 - 1.5e-18 66.4 7.8 8.8e-18 63.9 5.7 3.0 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RUS77143.1 - 9.6e-07 28.5 0.5 0.00013 21.7 0.1 2.9 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 RUS77143.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus NQRA PF05896.11 RUS77143.1 - 0.0016 18.0 0.9 0.004 16.6 0.9 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 RUS77143.1 - 0.0026 17.7 1.4 0.0072 16.3 0.3 2.2 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 RUS77143.1 - 0.0032 17.5 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 RUS77143.1 - 0.0059 15.9 0.4 0.068 12.4 0.5 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 RUS77143.1 - 0.0073 15.9 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 RUS77143.1 - 0.023 15.4 0.1 0.12 13.1 0.1 2.3 2 0 0 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.6 RUS77143.1 - 0.041 13.1 0.1 0.99 8.6 0.0 2.5 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp EGF PF00008.27 RUS77144.1 - 1.6e-11 44.2 54.7 8.6e-07 29.2 12.6 6.2 4 1 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 RUS77144.1 - 0.013 15.9 10.2 0.013 15.9 10.2 5.5 5 0 0 5 5 5 0 EGF-like domain hEGF PF12661.7 RUS77144.1 - 0.62 10.8 46.6 0.12 13.0 8.1 7.0 4 2 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.27 RUS77145.1 - 1.6e-07 31.4 13.1 1.6e-07 31.4 13.1 2.1 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 RUS77145.1 - 0.09 13.4 9.0 0.09 13.4 9.0 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 RUS77145.1 - 0.11 12.8 13.8 0.25 11.8 13.8 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 RUS77145.1 - 0.15 12.3 12.4 0.059 13.6 9.4 1.9 2 0 0 2 2 2 0 Calcium-binding EGF domain EGF PF00008.27 RUS77146.1 - 1.2e-06 28.7 11.9 1.2e-06 28.7 11.9 3.4 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 RUS77146.1 - 0.026 15.1 11.1 0.033 14.8 5.5 3.5 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 RUS77146.1 - 0.44 10.9 20.9 5.3 7.5 11.9 3.1 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 RUS77147.1 - 1.4e-11 44.4 52.0 1.8e-05 24.9 11.4 5.8 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 RUS77147.1 - 0.0068 17.0 8.3 0.0068 17.0 8.3 6.9 6 1 0 6 6 6 2 Human growth factor-like EGF EGF_CA PF07645.15 RUS77147.1 - 0.014 15.6 8.2 0.014 15.6 8.2 5.7 2 2 2 4 4 4 0 Calcium-binding EGF domain EGF_2 PF07974.13 RUS77147.1 - 0.018 15.4 11.3 0.018 15.4 11.3 6.2 6 0 0 6 6 6 0 EGF-like domain Bowman-Birk_leg PF00228.20 RUS77147.1 - 0.087 13.2 12.8 0.9 10.0 1.0 4.4 3 0 0 3 3 3 0 Bowman-Birk serine protease inhibitor family FCH PF00611.23 RUS77149.1 - 0.0013 18.9 1.6 0.0065 16.7 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4142 PF13628.6 RUS77149.1 - 0.15 12.3 3.4 0.58 10.4 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4142) Kinesin PF00225.23 RUS77150.1 - 1.6e-78 264.0 0.0 1.6e-78 264.0 0.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain TPR_MLP1_2 PF07926.12 RUS77150.1 - 0.0084 16.2 6.3 0.0084 16.2 6.3 6.7 4 2 3 7 7 7 1 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 RUS77150.1 - 0.0099 16.2 2.4 0.0099 16.2 2.4 9.1 7 2 3 10 10 10 1 Csm1 N-terminal domain CLZ PF16526.5 RUS77150.1 - 0.045 14.1 0.5 0.045 14.1 0.5 7.2 6 2 2 8 8 8 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CwsA PF10814.8 RUS77150.1 - 0.071 13.3 4.4 0.25 11.5 2.7 3.0 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA LURAP PF14854.6 RUS77150.1 - 3.6 7.6 9.9 7.5 6.5 1.3 3.6 2 1 1 3 3 3 0 Leucine rich adaptor protein WD40 PF00400.32 RUS77152.1 - 9.2e-25 86.4 5.9 0.0013 19.5 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 RUS77152.1 - 0.046 13.8 0.0 4.2 7.5 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PATR PF12951.7 RUS77152.1 - 0.14 12.3 2.6 1.4 9.1 0.0 3.4 3 1 0 3 3 3 0 Passenger-associated-transport-repeat DUF1647 PF07801.11 RUS77154.1 - 3.5e-05 23.6 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) AAA_16 PF13191.6 RUS77155.1 - 3.2e-08 34.1 0.4 3.3e-05 24.4 0.0 4.1 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 RUS77155.1 - 6.2e-07 29.5 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 RUS77155.1 - 1.2e-05 26.0 4.9 0.00054 20.7 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77155.1 - 4.7e-05 23.6 0.2 1.6 9.1 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 RUS77155.1 - 5.2e-05 23.5 0.0 0.0002 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 RUS77155.1 - 0.0066 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Nup160 PF11715.8 RUS77155.1 - 0.023 13.3 0.6 0.86 8.2 0.1 3.4 3 1 2 5 5 5 0 Nucleoporin Nup120/160 ATPase_2 PF01637.18 RUS77155.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 RUS77155.1 - 0.04 14.4 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pil1 PF13805.6 RUS77157.1 - 1e-08 35.0 8.0 1.5e-08 34.5 8.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 RUS77157.1 - 0.022 14.5 12.5 0.016 14.9 8.2 2.0 1 1 1 2 2 2 0 BAR domain of APPL family DUF438 PF04282.13 RUS77157.1 - 0.11 12.5 0.8 0.32 11.0 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF438) RNA_pol_N PF01194.17 RUS77158.1 - 5.5e-33 113.1 0.5 7.1e-33 112.7 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit zf-CCHC PF00098.23 RUS77159.1 - 2.9e-06 27.1 0.5 8.4e-06 25.6 0.5 1.9 1 0 0 1 1 1 1 Zinc knuckle SNCAIP_SNCA_bd PF16700.5 RUS77159.1 - 0.27 11.0 1.2 0.42 10.4 0.2 1.8 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DnaJ_CXXCXGXG PF00684.19 RUS77160.1 - 0.0022 18.3 31.6 0.23 11.8 6.2 2.7 1 1 2 3 3 3 3 DnaJ central domain DUF5351 PF17302.2 RUS77160.1 - 2.3 8.5 28.9 0.24 11.6 1.2 5.2 4 1 1 5 5 5 0 Family of unknown function (DUF5351) zf-C4 PF00105.18 RUS77161.1 - 3.7e-32 110.6 16.5 6.4e-32 109.8 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS77161.1 - 4.4e-30 104.8 0.0 8.7e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SPT6_acidic PF14632.6 RUS77161.1 - 0.092 13.3 0.2 0.17 12.5 0.2 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 ANAPC_CDC26 PF10471.9 RUS77162.1 - 0.068 14.0 30.7 0.99 10.3 3.8 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 HNOBA PF07701.14 RUS77162.1 - 0.85 9.0 6.1 1.3 8.4 0.2 2.9 3 0 0 3 3 3 0 Heme NO binding associated Spt20 PF12090.8 RUS77162.1 - 1.1 8.8 37.0 1.5 8.4 7.4 3.2 3 0 0 3 3 3 0 Spt20 family DegT_DnrJ_EryC1 PF01041.17 RUS77163.1 - 9.3e-27 94.3 0.0 1.6e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GLTP PF08718.11 RUS77164.1 - 7.3e-45 152.9 0.1 1.2e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.29 RUS77164.1 - 3.3e-14 53.3 0.0 9.3e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RUS77164.1 - 3.8e-06 27.3 0.1 1.8e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RUS77164.1 - 5.7e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Pox_I1 PF03289.13 RUS77164.1 - 0.052 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus protein I1 PP2C PF00481.21 RUS77165.1 - 2.2e-39 135.7 9.5 2.5e-32 112.5 1.3 3.5 1 1 1 2 2 2 2 Protein phosphatase 2C RNase_H PF00075.24 RUS77166.1 - 2.7e-06 27.6 0.1 6.3e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 RNase H Ras PF00071.22 RUS77167.1 - 2.8e-44 150.6 0.1 3.3e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS77167.1 - 1.5e-24 86.6 0.0 2.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS77167.1 - 1.7e-12 47.1 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS77167.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS77167.1 - 4e-05 23.2 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 RUS77167.1 - 7.6e-05 22.2 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ELL PF10390.9 RUS77167.1 - 0.047 13.2 0.1 0.075 12.5 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL ABC_tran_CTD PF16326.5 RUS77168.1 - 0.17 12.2 1.1 0.37 11.1 1.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4164 PF13747.6 RUS77168.1 - 0.24 11.7 7.1 0.16 12.3 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) RapA_C PF12137.8 RUS77168.1 - 0.27 10.2 6.3 0.41 9.6 6.3 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal BshC PF10079.9 RUS77168.1 - 0.3 9.8 5.1 0.45 9.2 5.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 RUS77168.1 - 0.38 10.3 4.0 0.59 9.6 4.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 RUS77168.1 - 0.43 10.4 7.0 0.92 9.4 3.2 1.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain KxDL PF10241.9 RUS77168.1 - 0.66 10.3 6.5 0.67 10.3 1.5 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein TMPIT PF07851.13 RUS77168.1 - 6.9 5.8 6.8 11 5.2 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-H2C2_2 PF13465.6 RUS77170.1 - 2.3e-14 53.1 10.0 2.6e-09 37.1 2.6 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS77170.1 - 6.1e-11 42.1 33.9 0.00021 21.6 0.9 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77170.1 - 2.7e-05 24.6 10.2 0.00018 22.0 2.6 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RUS77170.1 - 0.099 12.8 0.1 0.099 12.8 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Lectin_C PF00059.21 RUS77171.1 - 4.2e-28 98.2 0.0 1.5e-14 54.7 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain LRR_6 PF13516.6 RUS77172.1 - 9.6e-12 44.0 1.9 0.0016 18.3 0.0 4.5 4 0 0 4 4 4 4 Leucine Rich repeat PS_pyruv_trans PF04230.13 RUS77173.1 - 1.7e-16 61.0 0.2 4.4e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase TPT PF03151.16 RUS77173.1 - 2.7e-06 27.0 3.5 0.003 17.0 0.6 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nepo_coat_N PF03689.15 RUS77173.1 - 1.5 8.9 4.1 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Nepovirus coat protein, N-terminal domain PS_pyruv_trans PF04230.13 RUS77174.1 - 3.7e-16 59.9 0.3 4.4e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase TPT PF03151.16 RUS77174.1 - 5.6e-16 58.7 17.7 1.2e-15 57.6 17.7 1.6 1 0 0 1 1 1 1 Triose-phosphate Transporter family RT_RNaseH_2 PF17919.1 RUS77175.1 - 5.1e-14 52.1 0.6 1e-11 44.7 0.6 2.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS77175.1 - 3.2e-08 33.8 0.4 1.4e-07 31.8 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase TPT PF03151.16 RUS77176.1 - 0.0077 15.6 1.8 0.011 15.1 1.8 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF1758 PF05585.12 RUS77177.1 - 1.7e-09 37.7 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease_2 PF13650.6 RUS77177.1 - 1.5e-07 31.9 0.0 2.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS77177.1 - 3.4e-06 27.5 0.0 8.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ABC_tran PF00005.27 RUS77177.1 - 0.018 15.6 0.2 5.4 7.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Asp_protease PF09668.10 RUS77177.1 - 0.055 13.3 0.2 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 RUS77177.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease PS_pyruv_trans PF04230.13 RUS77178.1 - 3.1e-17 63.4 0.2 2.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase MoaC PF01967.21 RUS77179.1 - 1.2e-45 154.9 5.4 1.9e-45 154.3 5.4 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 RUS77179.1 - 1.1e-38 132.0 0.0 2.9e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 RUS77179.1 - 1.1e-28 100.7 0.0 1.8e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 RUS77179.1 - 3.6e-07 30.5 0.0 9.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 RUS77179.1 - 0.0045 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain EF-hand_6 PF13405.6 RUS77181.1 - 2e-09 36.6 4.8 9.1e-06 25.2 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS77181.1 - 6.9e-08 32.8 8.6 6.5e-07 29.7 1.5 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS77181.1 - 1.8e-05 23.9 0.0 1.8e-05 23.9 0.0 4.3 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 RUS77181.1 - 3.7e-05 23.5 2.1 0.00024 20.9 0.5 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_11 PF08976.11 RUS77181.1 - 0.0045 17.8 0.0 0.0073 17.2 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain EF-hand_9 PF14658.6 RUS77181.1 - 0.015 15.6 0.0 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF4170 PF13773.6 RUS77181.1 - 0.09 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) EFhand_Ca_insen PF08726.10 RUS77181.1 - 0.1 12.7 0.1 0.85 9.8 0.0 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 RUS77181.1 - 1 9.0 0.0 1 9.0 0.0 3.6 4 1 1 5 5 5 0 EF hand EF-hand_7 PF13499.6 RUS77182.1 - 3.1e-10 40.4 1.5 4.3e-10 39.9 1.5 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS77182.1 - 8e-07 28.5 0.2 2.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS77182.1 - 5.2e-06 25.6 0.8 1.9e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 RUS77182.1 - 1.1e-05 25.2 2.8 0.00028 20.7 0.8 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_11 PF08976.11 RUS77182.1 - 0.015 16.1 0.0 0.019 15.8 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Neur_chan_memb PF02932.16 RUS77183.1 - 7.4e-19 68.7 0.0 1.5e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS77183.1 - 2.1e-17 63.3 1.3 2.6e-17 63.0 1.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Bunya_NS-S PF01104.17 RUS77184.1 - 0.32 10.9 9.1 1.5 8.7 3.3 2.8 1 1 1 2 2 2 0 Bunyavirus non-structural protein NS-s TAS2R PF05296.13 RUS77184.1 - 3.6 6.6 24.1 26 3.8 9.0 2.8 1 1 1 2 2 2 0 Taste receptor protein (TAS2R) TFIID-31kDa PF02291.15 RUS77185.1 - 5.1e-48 162.2 0.1 8.2e-48 161.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 RUS77185.1 - 4.9e-08 33.2 0.1 8.1e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RUS77185.1 - 6.1e-06 26.3 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 RUS77185.1 - 8.6e-06 26.1 0.1 2.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 RUS77185.1 - 3.2e-05 23.9 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 RUS77185.1 - 8e-05 22.8 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hs1pro-1_N PF07231.12 RUS77185.1 - 0.1 12.3 1.3 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Hs1pro-1 N-terminus TIP49_C PF17856.1 RUS77185.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 AAA-lid domain Mito_carr PF00153.27 RUS77186.1 - 1.3e-66 220.5 1.0 5.5e-21 74.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Scramblase PF03803.15 RUS77187.1 - 2.5e-62 210.1 4.0 1.1e-61 207.9 4.0 1.8 1 1 0 1 1 1 1 Scramblase FA_desaturase PF00487.24 RUS77188.1 - 1.4e-27 97.1 23.4 2.3e-27 96.4 23.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Spec3 PF15795.5 RUS77188.1 - 0.69 10.5 7.0 0.93 10.1 3.7 2.5 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein Gal-bind_lectin PF00337.22 RUS77189.1 - 5.3e-10 38.9 0.0 8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin PAN_4 PF14295.6 RUS77189.1 - 0.0015 18.4 1.3 0.0031 17.4 1.3 1.5 1 0 0 1 1 1 1 PAN domain Melibiase_2 PF16499.5 RUS77191.1 - 4.9e-138 459.0 2.7 5.9e-138 458.8 2.7 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 RUS77191.1 - 6.5e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 RUS77191.1 - 2.3e-05 24.4 0.0 5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 RUS77191.1 - 0.0075 15.3 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 RUS77191.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 RE_AspBHI_N PF18062.1 RUS77191.1 - 0.2 11.2 0.7 0.35 10.4 0.7 1.3 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal 7tm_1 PF00001.21 RUS77192.1 - 1.1e-11 44.6 24.1 1.3e-11 44.3 24.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS77192.1 - 1.9e-08 34.3 22.4 1.9e-08 34.3 22.4 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3681 PF12442.8 RUS77192.1 - 0.38 11.2 4.3 0.24 11.9 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3681) bZIP_2 PF07716.15 RUS77193.1 - 1.9e-08 34.2 11.6 1.9e-08 34.2 11.6 2.8 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS77193.1 - 7.5e-07 29.2 16.5 2e-06 27.8 12.4 2.4 2 0 0 2 2 2 1 bZIP transcription factor FliJ PF02050.16 RUS77193.1 - 0.76 10.0 9.3 1.6 8.9 5.8 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein HALZ PF02183.18 RUS77193.1 - 0.98 9.7 7.2 6.4 7.1 1.9 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 RUS77193.1 - 4.9 7.8 7.1 3.5 8.2 3.4 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TGF_beta PF00019.20 RUS77194.1 - 7.2e-12 46.2 0.0 1.5e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Fucose_iso_N1 PF07881.12 RUS77195.1 - 8.9e-07 28.9 1.0 0.17 11.7 0.1 3.4 1 1 2 3 3 3 3 L-fucose isomerase, first N-terminal domain Nup54_C PF18437.1 RUS77195.1 - 5.5e-05 23.0 4.4 2.7 8.0 0.1 4.0 2 2 2 4 4 4 4 Nup54 C-terminal interacting domain Apolipoprotein PF01442.18 RUS77195.1 - 0.058 13.3 5.9 0.071 13.0 5.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 RUS77196.1 - 1.4e-15 57.1 10.7 1.5e-15 57.0 10.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DoxX_2 PF13564.6 RUS77196.1 - 1.4 9.1 6.8 0.62 10.2 3.3 2.2 2 1 0 2 2 2 0 DoxX-like family MFS_1 PF07690.16 RUS77197.1 - 3e-07 29.7 15.1 4.7e-07 29.1 15.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS77197.1 - 0.0026 16.7 7.5 0.11 11.4 2.8 2.9 1 1 2 3 3 3 3 MFS_1 like family LapA_dom PF06305.11 RUS77197.1 - 0.039 13.8 3.5 6 6.8 1.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_3 PF05977.13 RUS77197.1 - 0.073 11.5 1.1 0.099 11.0 1.1 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector DUF2834 PF11196.8 RUS77197.1 - 0.14 12.5 1.9 3.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) Peptidase_M50B PF13398.6 RUS77197.1 - 0.64 9.6 7.6 0.06 13.0 1.2 2.2 2 1 1 3 3 3 0 Peptidase M50B-like NYD-SP28 PF14772.6 RUS77198.1 - 3.2e-29 100.9 15.2 3.2e-29 100.9 15.2 6.7 5 1 3 8 8 8 1 Sperm tail NYD-SP28_assoc PF14775.6 RUS77198.1 - 1.3e-21 76.4 8.1 1.3e-21 76.4 8.1 3.9 3 1 2 5 5 5 1 Sperm tail C-terminal domain PikAIV_N PF18605.1 RUS77198.1 - 0.042 13.4 3.1 0.35 10.5 1.5 3.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain GerPC PF10737.9 RUS77198.1 - 0.36 10.9 29.6 0.84 9.7 8.8 4.0 3 2 0 3 3 3 0 Spore germination protein GerPC Mga PF05043.13 RUS77198.1 - 3.8 8.2 9.3 1 10.0 4.4 2.8 2 0 0 2 2 2 0 Mga helix-turn-helix domain Pribosyltran PF00156.27 RUS77199.1 - 9.7e-10 38.2 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 RUS77199.1 - 1.4e-07 31.5 0.0 6.3e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RUS77199.1 - 6e-06 26.4 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain PRTase_2 PF15609.6 RUS77199.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyl transferase Receptor_2B4 PF11465.8 RUS77200.1 - 0.016 15.4 9.9 15 5.9 0.0 5.0 1 1 6 7 7 7 0 Natural killer cell receptor 2B4 EF-hand_1 PF00036.32 RUS77201.1 - 2.3e-17 61.2 2.1 4.1e-08 32.2 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS77201.1 - 3.2e-17 62.7 0.3 5.5e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS77201.1 - 1.1e-15 56.1 0.1 8.3e-08 31.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS77201.1 - 8.9e-13 47.9 2.5 6.7e-09 35.5 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS77201.1 - 1.4e-12 46.5 0.5 3.5e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 RUS77201.1 - 0.00016 21.5 0.4 0.00084 19.2 0.1 2.0 1 1 1 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 RUS77201.1 - 0.001 19.3 0.6 0.0016 18.8 0.1 1.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 RUS77201.1 - 0.0029 17.8 1.2 0.0036 17.5 1.0 1.2 1 1 0 1 1 1 1 p25-alpha LNS2 PF08235.13 RUS77201.1 - 0.0045 16.5 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) EF-hand_14 PF17959.1 RUS77201.1 - 0.0062 16.9 0.2 0.0094 16.3 0.2 1.4 1 1 0 1 1 1 1 EF-hand domain DUF3879 PF12995.7 RUS77201.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) EF-hand_11 PF08976.11 RUS77201.1 - 0.026 15.4 0.1 0.029 15.2 0.1 1.1 1 0 0 1 1 1 0 EF-hand domain DUF1456 PF07308.13 RUS77201.1 - 0.035 14.4 0.2 0.086 13.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) S_100 PF01023.19 RUS77201.1 - 0.049 13.3 1.0 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DUF3970 PF13113.6 RUS77201.1 - 0.08 13.2 1.3 12 6.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3970) UPF0154 PF03672.13 RUS77201.1 - 0.082 12.9 2.4 0.82 9.7 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 RUS77201.1 - 0.15 12.8 0.0 0.29 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) Ribosomal_L7Ae PF01248.26 RUS77203.1 - 8e-25 86.4 0.0 9.6e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 RUS77203.1 - 0.031 14.4 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 RUS77205.1 - 1e-11 44.4 8.3 1.2e-11 44.1 8.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS77205.1 - 0.00076 18.4 0.8 0.1 11.5 0.5 2.1 2 0 0 2 2 2 2 MFS_1 like family BT1 PF03092.16 RUS77205.1 - 0.0026 16.0 0.3 0.0034 15.7 0.3 1.2 1 0 0 1 1 1 1 BT1 family LacY_symp PF01306.19 RUS77205.1 - 0.0058 15.4 9.6 0.021 13.6 4.4 2.0 1 1 1 2 2 2 2 LacY proton/sugar symporter MFS_1 PF07690.16 RUS77206.1 - 2.9e-16 59.4 26.4 3.4e-16 59.1 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RCC1 PF00415.18 RUS77207.1 - 1.9e-55 185.3 11.3 4e-11 43.3 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS77207.1 - 2.9e-24 84.3 32.6 2.2e-08 33.7 0.6 7.9 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat TcpA PF05946.12 RUS77207.1 - 0.049 13.7 0.2 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA Pkinase PF00069.25 RUS77208.1 - 4.7e-71 239.2 0.1 8.9e-71 238.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77208.1 - 4.2e-51 173.7 0.0 7e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 RUS77208.1 - 2.4e-24 85.1 3.1 2.4e-24 85.1 3.1 2.0 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 RUS77208.1 - 1.3e-08 34.1 2.9 2.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS77208.1 - 0.011 15.0 0.0 0.065 12.5 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Macoilin PF09726.9 RUS77208.1 - 0.083 11.4 8.7 0.12 11.0 8.7 1.1 1 0 0 1 1 1 0 Macoilin family Abi_2 PF07751.11 RUS77208.1 - 0.11 12.8 2.2 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 Abi-like protein TERB2 PF15101.6 RUS77208.1 - 0.29 11.1 6.1 0.65 10.0 6.1 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2098 PF09871.9 RUS77208.1 - 0.53 10.7 4.7 34 4.9 2.7 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Haspin_kinase PF12330.8 RUS77208.1 - 0.6 9.0 7.8 0.055 12.4 0.3 2.5 2 1 0 2 2 2 0 Haspin like kinase domain Presenilin PF01080.17 RUS77208.1 - 0.78 8.4 8.5 1 8.0 8.5 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 RUS77208.1 - 1.3 9.7 18.7 0.78 10.4 14.2 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 RUS77208.1 - 6.9 6.4 14.0 11 5.7 14.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CUB PF00431.20 RUS77209.1 - 6.9e-19 68.2 0.3 1.1e-18 67.6 0.3 1.3 1 0 0 1 1 1 1 CUB domain Herpes_glycop PF01528.16 RUS77209.1 - 0.039 12.8 0.1 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus glycoprotein M DUF485 PF04341.12 RUS77209.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SKG6 PF08693.10 RUS77209.1 - 0.081 12.3 0.6 0.22 11.0 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SVM_signal PF12113.8 RUS77209.1 - 0.75 9.7 2.2 1.2 9.1 2.2 1.3 1 0 0 1 1 1 0 SVM protein signal sequence 7tm_1 PF00001.21 RUS77210.1 - 3.6e-10 39.6 0.0 4.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TetR_C_29 PF17938.1 RUS77210.1 - 0.17 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tmemb_cc2 PF10267.9 RUS77212.1 - 1.5e-54 185.7 13.4 1.7e-54 185.6 13.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 RUS77212.1 - 0.001 18.1 2.8 0.0011 17.9 2.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein HxlR PF01638.17 RUS77212.1 - 0.012 15.4 0.3 0.023 14.5 0.2 1.5 1 1 0 1 1 1 0 HxlR-like helix-turn-helix Prominin PF05478.11 RUS77212.1 - 0.021 12.8 3.5 0.025 12.6 3.5 1.1 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 RUS77212.1 - 0.036 13.5 12.4 0.048 13.1 12.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fzo_mitofusin PF04799.13 RUS77212.1 - 0.061 12.9 7.5 0.06 12.9 6.2 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF1258 PF06869.12 RUS77212.1 - 0.14 11.6 1.1 0.31 10.5 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Spc7 PF08317.11 RUS77212.1 - 0.2 10.5 9.2 0.22 10.4 9.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 RUS77212.1 - 0.24 11.7 9.9 0.61 10.4 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4349 PF14257.6 RUS77212.1 - 0.41 10.1 10.1 0.84 9.0 10.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Exonuc_VII_L PF02601.15 RUS77212.1 - 0.8 9.2 6.8 0.88 9.1 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 RUS77212.1 - 1.2 9.3 8.6 2.1 8.5 4.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ACCA PF03255.14 RUS77212.1 - 1.3 8.9 4.9 1.9 8.3 4.8 1.3 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit XhlA PF10779.9 RUS77212.1 - 1.5 9.0 12.6 26 5.1 2.2 3.0 1 1 1 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 RUS77212.1 - 2 8.8 13.7 2.4 8.6 0.9 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 RUS77212.1 - 2.6 8.2 21.2 0.24 11.5 4.4 2.9 1 1 2 3 3 3 0 TolA binding protein trimerisation SCRL PF06876.12 RUS77214.1 - 6.2 7.1 12.4 9.7 6.5 6.8 2.8 3 0 0 3 3 3 0 Plant self-incompatibility response (SCRL) protein Ribophorin_II PF05817.14 RUS77215.1 - 1.4e-186 621.8 9.7 1.6e-186 621.6 9.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Sipho_tail PF05709.11 RUS77215.1 - 0.028 13.8 0.3 0.1 12.0 0.1 1.8 2 0 0 2 2 2 0 Phage tail protein SPX PF03105.19 RUS77217.1 - 0.00076 19.5 6.1 0.001 19.1 6.1 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 RUS77217.1 - 0.0074 15.2 6.3 0.011 14.7 6.3 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 RUS77217.1 - 0.21 10.1 12.6 0.28 9.7 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 RUS77217.1 - 0.44 9.0 10.6 0.57 8.6 10.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 YTH PF04146.15 RUS77217.1 - 0.7 9.8 7.3 0.98 9.3 7.3 1.4 1 1 0 1 1 1 0 YT521-B-like domain Plasmodium_Vir PF05795.11 RUS77217.1 - 0.76 9.1 6.1 1.1 8.6 6.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAP1 PF08601.10 RUS77217.1 - 4.7 6.9 19.1 7.1 6.3 19.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Peptidase_M20 PF01546.28 RUS77218.1 - 1.5e-36 126.0 0.0 2.8e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RUS77218.1 - 3e-14 52.9 0.0 8.7e-14 51.4 0.0 1.8 1 1 1 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RUS77218.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 GFO_IDH_MocA PF01408.22 RUS77219.1 - 9e-17 62.0 0.0 2e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RUS77219.1 - 3.3e-05 23.9 0.0 8.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 RUS77219.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 RUS77219.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ANAPC4_WD40 PF12894.7 RUS77220.1 - 1.1e-10 41.6 0.0 0.0006 20.1 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS77220.1 - 2.2e-08 34.6 2.6 1.7 9.6 0.0 7.8 8 0 0 8 8 8 2 WD domain, G-beta repeat WD40_like PF17005.5 RUS77220.1 - 0.00014 21.3 3.3 0.18 11.1 0.0 3.1 3 0 0 3 3 3 2 WD40-like domain Pannexin_like PF12534.8 RUS77220.1 - 2.4 7.1 5.4 7.6 5.5 5.4 1.9 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 HMG_box PF00505.19 RUS77222.1 - 4.8e-28 97.4 3.5 7.4e-28 96.8 3.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS77222.1 - 9.1e-11 42.2 1.5 1.5e-10 41.5 1.5 1.3 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 RUS77222.1 - 7.2e-07 30.2 0.7 7.2e-07 30.2 0.7 2.4 2 1 0 2 2 2 1 SOX transcription factor AAA PF00004.29 RUS77223.1 - 1.1e-63 213.6 0.0 2e-43 148.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS77223.1 - 6.8e-10 39.6 11.7 0.0015 19.0 0.4 4.6 3 2 2 5 5 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 RUS77223.1 - 3.4e-09 36.4 0.1 8.1e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 RUS77223.1 - 5.2e-09 36.2 0.0 3.1e-06 27.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 RUS77223.1 - 1e-07 32.2 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 RUS77223.1 - 2e-07 31.1 1.8 0.00028 20.8 0.1 3.6 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 RUS77223.1 - 4.5e-07 30.5 0.1 0.029 14.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RUS77223.1 - 5.8e-07 29.6 0.5 0.045 13.7 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RUS77223.1 - 8.5e-07 29.3 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 RUS77223.1 - 1.8e-06 27.8 0.0 0.00013 21.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 RUS77223.1 - 2.3e-06 27.6 0.1 0.036 14.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RUS77223.1 - 5.7e-06 26.6 5.3 0.0078 16.5 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_2 PF07724.14 RUS77223.1 - 6.8e-06 26.3 0.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 RUS77223.1 - 7.6e-06 25.4 0.6 0.0062 15.8 0.0 2.5 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_25 PF13481.6 RUS77223.1 - 8.2e-06 25.5 1.7 0.47 10.0 0.0 4.1 3 1 1 4 4 4 2 AAA domain Mg_chelatase PF01078.21 RUS77223.1 - 1.3e-05 24.7 0.2 0.067 12.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RUS77223.1 - 2.6e-05 23.5 0.0 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 RUS77223.1 - 3e-05 24.0 0.1 0.073 13.0 0.2 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_24 PF13479.6 RUS77223.1 - 3e-05 23.8 0.1 0.058 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RUS77223.1 - 7.5e-05 22.3 0.0 0.062 12.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 RUS77223.1 - 8.8e-05 22.9 1.2 0.026 14.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 RUS77223.1 - 0.00036 20.5 2.0 0.1 12.5 0.0 3.6 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 RUS77223.1 - 0.00046 20.5 1.0 0.9 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RUS77223.1 - 0.0005 19.8 0.1 0.065 13.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA12 PF10443.9 RUS77223.1 - 0.00054 18.8 0.2 0.0021 16.9 0.0 1.8 2 0 0 2 2 2 1 RNA12 protein AAA_23 PF13476.6 RUS77223.1 - 0.00055 20.5 0.1 0.0022 18.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 RUS77223.1 - 0.00092 19.7 0.0 0.045 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 RUS77223.1 - 0.0022 17.7 0.3 0.44 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 RUS77223.1 - 0.0032 17.4 0.7 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 NTPase ResIII PF04851.15 RUS77223.1 - 0.0036 17.3 0.0 0.63 10.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 RUS77223.1 - 0.0041 16.2 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 RUS77223.1 - 0.0049 16.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 RUS77223.1 - 0.0074 16.1 0.2 0.47 10.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 RUS77223.1 - 0.013 15.9 0.2 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 RUS77223.1 - 0.031 13.5 0.2 0.64 9.2 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RUS77223.1 - 0.032 13.6 0.4 0.91 8.8 0.0 2.4 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 RUS77223.1 - 0.037 13.5 1.0 4.4 6.7 0.0 3.0 3 1 0 3 3 2 0 PhoH-like protein Zeta_toxin PF06414.12 RUS77223.1 - 0.037 13.3 0.2 4 6.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 RUS77223.1 - 0.039 13.7 0.2 5.4 6.7 0.1 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 RUS77223.1 - 0.04 13.5 1.8 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_3 PF07726.11 RUS77223.1 - 0.044 13.6 0.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 RUS77223.1 - 0.074 12.9 0.0 3.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein NB-ARC PF00931.22 RUS77223.1 - 0.076 12.2 0.0 9 5.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain VCX_VCY PF15231.6 RUS77224.1 - 1.6e-06 28.8 0.0 3.9 8.2 0.0 4.4 1 1 3 4 4 4 4 Variable charge X/Y family P4Ha_N PF08336.11 RUS77224.1 - 0.00021 21.3 7.2 23 5.0 0.2 7.5 1 1 4 5 5 5 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1852 PF08908.11 RUS77224.1 - 1.1 8.2 4.7 46 2.9 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF1852) BPS PF08947.10 RUS77224.1 - 6 6.8 16.7 68 3.4 0.3 8.0 3 2 4 9 9 9 0 BPS (Between PH and SH2) Synapsin PF02078.16 RUS77225.1 - 0.0021 18.3 0.0 5.9 7.2 0.0 2.9 1 1 2 3 3 3 2 Synapsin, N-terminal domain Helo_like_N PF17111.5 RUS77225.1 - 0.014 14.7 2.2 4 6.7 0.2 3.5 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins HTH_51 PF18558.1 RUS77225.1 - 0.03 14.2 1.7 1.5e+02 2.3 0.0 4.7 1 1 7 8 8 8 0 Helix-turn-helix domain SepZ PF06066.11 RUS77225.1 - 0.04 14.1 13.4 11 6.3 0.3 4.7 1 1 4 5 5 5 0 SepZ Nrap_D4 PF17405.2 RUS77225.1 - 0.059 12.7 0.0 15 4.8 0.0 2.9 1 1 2 3 3 3 0 Nrap protein nucleotidyltransferase domain 4 fn3_5 PF06280.12 RUS77225.1 - 0.12 13.1 0.6 16 6.2 0.5 3.6 1 1 1 2 2 2 0 Fn3-like domain Mrr_cat PF04471.12 RUS77225.1 - 0.14 12.2 3.8 22 5.1 0.2 3.6 1 1 1 3 3 3 0 Restriction endonuclease Ldh_1_N PF00056.23 RUS77226.1 - 4e-09 36.7 0.0 7.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RUS77226.1 - 2.1e-08 34.3 0.0 4.7e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TSP_1 PF00090.19 RUS77227.1 - 3.8e-19 68.6 42.4 1.2e-09 38.2 9.6 4.1 4 0 0 4 4 4 3 Thrombospondin type 1 domain SRP-alpha_N PF04086.13 RUS77229.1 - 8.9e-59 199.8 1.5 1.2e-58 199.4 1.5 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 RUS77229.1 - 5.4e-48 163.2 0.1 2.2e-47 161.2 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 RUS77229.1 - 2.6e-09 37.2 0.6 7.9e-09 35.6 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 RUS77229.1 - 0.00013 22.0 0.0 0.00067 19.7 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 RUS77229.1 - 0.00019 20.5 0.0 0.0004 19.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 RUS77229.1 - 0.0059 16.5 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 RUS77229.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RUS77229.1 - 0.024 14.9 0.0 0.086 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain SRX PF09201.10 RUS77229.1 - 0.033 14.0 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit Fer4_NifH PF00142.18 RUS77229.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.6 RUS77229.1 - 0.076 12.8 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 RUS77229.1 - 0.1 11.8 0.1 0.28 10.3 0.1 1.6 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 RUS77229.1 - 0.23 11.6 1.0 1.4 9.0 0.4 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase RPN2_C PF18004.1 RUS77229.1 - 0.7 9.8 9.3 1.4 8.8 9.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DHHC PF01529.20 RUS77231.1 - 5.1e-38 130.2 6.1 5.1e-38 130.2 6.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase 7tm_7 PF08395.12 RUS77231.1 - 0.033 13.4 0.5 0.033 13.4 0.5 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF3464 PF11947.8 RUS77231.1 - 0.064 13.0 0.3 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Apolipoprotein PF01442.18 RUS77232.1 - 1.6e-05 24.9 1.8 0.00049 20.0 1.3 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.10 RUS77232.1 - 0.0011 19.1 21.4 0.3 11.2 1.8 4.8 2 2 1 4 4 4 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.7 RUS77232.1 - 0.0039 17.7 15.5 4.8e+03 -1.8 15.5 4.4 1 1 0 1 1 1 0 YtxH-like protein Phasin_2 PF09361.10 RUS77232.1 - 0.0047 17.2 5.3 3.3 8.0 0.9 3.3 2 1 0 3 3 3 2 Phasin protein ApoLp-III PF07464.11 RUS77232.1 - 0.0065 16.6 5.3 0.062 13.4 1.3 2.8 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Mis12 PF05859.12 RUS77232.1 - 0.0068 16.5 8.4 7.8 6.6 0.4 3.7 1 1 1 2 2 2 0 Mis12 protein DUF883 PF05957.13 RUS77232.1 - 0.0095 16.5 12.1 1 10.0 0.7 3.7 1 1 3 4 4 4 3 Bacterial protein of unknown function (DUF883) SesA PF17107.5 RUS77232.1 - 0.0098 16.1 4.8 1.2 9.3 0.3 3.1 1 1 2 3 3 3 2 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 RUS77232.1 - 0.011 15.7 0.7 0.011 15.7 0.7 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF842 PF05811.13 RUS77232.1 - 0.06 13.0 0.0 3.7 7.2 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Phasin PF05597.11 RUS77232.1 - 0.07 13.1 7.5 3.6 7.6 0.2 3.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.11 RUS77232.1 - 0.13 10.2 1.3 0.25 9.3 1.3 1.4 1 1 0 1 1 1 0 Prominin DUF445 PF04286.12 RUS77232.1 - 0.18 11.6 3.7 1.9 8.2 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF1548 PF07579.11 RUS77232.1 - 0.33 11.3 0.6 39 4.6 0.0 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1548) EspB PF05802.11 RUS77232.1 - 0.47 10.4 28.3 0.78 9.7 6.8 2.8 1 1 1 2 2 2 0 Enterobacterial EspB protein Senescence PF06911.12 RUS77232.1 - 0.5 10.7 10.5 0.33 11.3 3.9 2.5 2 1 0 2 2 2 0 Senescence-associated protein FAM25 PF15825.5 RUS77232.1 - 0.61 10.5 13.4 0.51 10.7 0.7 3.9 1 1 3 4 4 4 0 FAM25 family Tex_N PF09371.10 RUS77232.1 - 0.81 9.3 2.7 4.2 7.0 0.3 2.4 2 1 0 2 2 2 0 Tex-like protein N-terminal domain DUF1837 PF08878.11 RUS77232.1 - 1.1 9.0 9.6 1.3 8.8 0.7 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1837) WGG PF10273.9 RUS77232.1 - 3.7 8.3 9.5 7.5 7.3 2.6 3.2 1 1 1 3 3 3 0 Pre-rRNA-processing protein TSR2 Anti-adapt_IraP PF10796.9 RUS77232.1 - 7.2 7.3 12.6 4.5 7.9 0.3 4.3 2 2 3 5 5 5 0 Sigma-S stabilisation anti-adaptor protein T3SS_needle_F PF09392.10 RUS77232.1 - 8.3 6.7 12.5 23 5.2 1.1 4.4 3 1 1 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Tautomerase PF01361.21 RUS77232.1 - 8.8 6.3 6.5 12 6.0 1.2 3.6 2 1 0 3 3 3 0 Tautomerase enzyme PMEI PF04043.15 RUS77232.1 - 9 6.6 19.0 15 5.9 5.1 2.7 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Dyp_perox PF04261.12 RUS77233.1 - 5.4e-21 74.9 0.0 6.6e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family MFS_1 PF07690.16 RUS77235.1 - 1e-09 37.8 13.0 1.4e-09 37.4 13.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS77235.1 - 5.8e-06 25.4 0.1 6.6e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 MFS_1 like family DUF3915 PF13054.6 RUS77237.1 - 0.016 15.2 2.3 0.046 13.7 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3938 PF13074.6 RUS77237.1 - 1.7 9.0 5.9 17 5.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Phage_Gp23 PF10669.9 RUS77237.1 - 4.9 7.5 11.1 22 5.4 11.1 2.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FYVE PF01363.21 RUS77239.1 - 1.5e-06 28.2 5.2 3.9e-06 26.9 5.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger Poty_PP PF08440.10 RUS77239.1 - 0.049 12.7 0.1 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 Potyviridae polyprotein Siva PF05458.12 RUS77239.1 - 0.29 10.8 5.5 0.85 9.3 4.2 2.2 3 0 0 3 3 3 0 Cd27 binding protein (Siva) IBR PF01485.21 RUS77239.1 - 0.71 10.2 10.2 0.34 11.2 5.9 2.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 RUS77239.1 - 0.95 9.5 5.7 22 5.2 5.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon C1_4 PF07975.12 RUS77239.1 - 3.3 8.0 10.6 15 5.9 8.4 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain C1_2 PF03107.16 RUS77239.1 - 4.2 7.8 8.0 0.87 9.9 4.0 2.1 2 0 0 2 2 2 0 C1 domain PA26 PF04636.13 RUS77240.1 - 2.4 7.0 11.6 0.075 11.9 5.5 1.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) CHCH PF06747.13 RUS77241.1 - 0.0043 17.1 7.3 18 5.6 0.0 4.8 1 1 5 6 6 6 5 CHCH domain DUF4718 PF15842.5 RUS77241.1 - 0.0081 16.0 4.5 7.9 6.2 0.1 4.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4718) UBA PF00627.31 RUS77243.1 - 1.6e-10 40.6 0.1 3.2e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 RUS77243.1 - 0.038 14.0 0.5 0.069 13.1 0.5 1.6 1 1 0 1 1 1 0 Rhomboid family DER1 PF04511.15 RUS77243.1 - 0.31 10.9 9.4 0.46 10.4 9.3 1.4 1 1 0 1 1 1 0 Der1-like family DUF1500 PF07389.12 RUS77244.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Roughex PF06020.11 RUS77247.1 - 0.0075 15.4 5.4 0.013 14.7 5.4 1.4 1 0 0 1 1 1 1 Drosophila roughex protein TFIIA PF03153.13 RUS77247.1 - 1.6 8.6 32.4 2.4 8.0 32.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 RUS77247.1 - 4.2 4.4 27.0 5 4.1 27.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP2C PF00481.21 RUS77249.1 - 3.1e-63 213.8 0.0 4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS77249.1 - 3.6e-08 33.3 0.2 2.2e-07 30.7 0.2 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C 7tm_1 PF00001.21 RUS77250.1 - 5e-19 68.6 18.0 7e-19 68.2 18.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS77250.1 - 0.00039 19.8 27.9 0.00087 18.7 2.2 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS77250.1 - 0.0032 16.9 26.7 0.025 14.0 17.9 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx GST_C_6 PF17171.4 RUS77250.1 - 0.019 14.7 0.4 0.047 13.5 0.4 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HLH PF00010.26 RUS77252.1 - 0.00023 21.1 0.1 0.00058 19.8 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 RUS77253.1 - 2e-07 30.8 0.5 4.2e-07 29.8 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VraX PF17412.2 RUS77253.1 - 0.0024 17.5 0.0 16 5.2 0.0 3.6 3 0 0 3 3 3 2 Family of unknown function HLH PF00010.26 RUS77254.1 - 4.4e-05 23.4 0.1 0.00013 21.9 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAM33 PF02330.16 RUS77256.1 - 0.023 14.7 1.4 0.032 14.2 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein Trypan_PARP PF05887.11 RUS77256.1 - 0.027 14.4 147.4 0.042 13.8 42.4 4.1 1 1 3 4 4 4 0 Procyclic acidic repetitive protein (PARP) Mpp10 PF04006.12 RUS77256.1 - 0.11 11.0 10.6 0.17 10.3 10.6 1.2 1 0 0 1 1 1 0 Mpp10 protein TFB6 PF17110.5 RUS77256.1 - 0.13 12.0 5.3 0.17 11.6 5.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RRN3 PF05327.11 RUS77256.1 - 0.14 10.6 16.3 0.17 10.4 16.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 RUS77256.1 - 0.53 9.6 13.7 0.7 9.2 13.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 RUS77256.1 - 1 7.4 38.1 1.3 7.0 38.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS77256.1 - 1.1 7.4 21.5 1.5 6.9 21.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS77256.1 - 1.1 7.5 17.4 1.4 7.1 17.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS77256.1 - 2.7 7.3 20.7 3.5 7.0 20.7 1.0 1 0 0 1 1 1 0 SDA1 I-set PF07679.16 RUS77257.1 - 3.5e-155 504.5 8.8 2.3e-17 62.8 0.1 13.3 13 0 0 13 13 13 13 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77257.1 - 6.3e-109 356.7 5.6 1.5e-10 41.5 0.0 13.4 13 0 0 13 13 13 13 Immunoglobulin domain Ig_2 PF13895.6 RUS77257.1 - 1.5e-60 201.5 4.0 5.7e-07 29.8 0.0 12.9 13 0 0 13 13 13 9 Immunoglobulin domain ig PF00047.25 RUS77257.1 - 4.7e-58 193.3 7.3 8.9e-06 25.8 0.2 12.1 12 0 0 12 12 12 11 Immunoglobulin domain V-set PF07686.17 RUS77257.1 - 1.2e-37 128.3 15.7 0.0022 18.2 0.0 15.9 11 5 1 12 12 12 8 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS77257.1 - 6.1e-21 74.3 1.1 0.12 12.4 0.0 9.7 10 0 0 10 10 10 6 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS77257.1 - 3.5e-10 40.1 8.7 0.096 13.1 0.1 10.7 10 1 0 10 10 9 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 RUS77257.1 - 2.4e-09 37.1 3.2 0.071 13.2 0.0 8.9 10 0 0 10 10 10 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS77257.1 - 2.8e-09 37.1 12.6 0.95 9.8 0.2 10.6 10 3 0 10 10 10 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 RUS77257.1 - 6.3e-09 36.1 4.1 2.3 8.7 0.5 8.1 7 0 0 7 7 7 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 RUS77257.1 - 4.2e-08 33.3 2.4 3.6 7.8 0.0 6.9 7 0 0 7 7 7 2 Natural killer cell receptor 2B4 Ig_6 PF18452.1 RUS77257.1 - 4.1e-06 26.2 0.0 10 5.7 0.0 6.6 7 0 0 7 7 7 1 Immunoglobulin domain ACAS_N PF16177.5 RUS77257.1 - 0.066 13.1 0.2 73 3.4 0.0 4.9 5 0 0 5 5 5 0 Acetyl-coenzyme A synthetase N-terminus SUIM_assoc PF16619.5 RUS77257.1 - 0.16 12.0 10.3 0.024 14.7 3.2 3.3 3 0 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 C2-set PF05790.15 RUS77257.1 - 0.21 11.8 8.4 1.4 9.2 0.0 5.1 5 0 0 5 5 3 0 Immunoglobulin C2-set domain Keratin_B2_2 PF13885.6 RUS77259.1 - 5.6e-08 32.6 18.9 67 3.5 18.9 3.5 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 RUS77259.1 - 1.6e-05 25.0 18.8 0.0035 17.4 7.8 2.1 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein ubiquitin PF00240.23 RUS77260.1 - 3.6e-21 74.7 0.1 6.9e-09 35.3 0.0 5.7 5 1 0 5 5 5 3 Ubiquitin family Rad60-SLD PF11976.8 RUS77260.1 - 2.4e-05 24.1 0.0 0.32 10.8 0.0 3.2 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS77260.1 - 0.00063 20.1 0.0 4.8 7.7 0.0 4.1 4 0 0 4 4 4 1 Ubiquitin-like domain Corona_3 PF04694.12 RUS77261.1 - 1.8e-08 34.6 3.4 14 6.1 0.0 6.0 1 1 5 6 6 6 4 Coronavirus ORF3 protein Spore_GerQ PF09671.10 RUS77261.1 - 3e-07 30.3 11.9 9.2 6.4 0.1 6.1 1 1 5 6 6 6 5 Spore coat protein (Spore_GerQ) Chorion_S16 PF05836.12 RUS77261.1 - 1.7e-06 28.2 0.1 44 4.4 0.0 5.6 1 1 5 6 6 6 0 Chorion protein S16 PV_NSP1 PF12433.8 RUS77261.1 - 0.54 10.6 10.3 15 6.0 0.2 4.0 1 1 5 6 6 6 0 Parvovirus non-structural protein 1 DUF3562 PF12085.8 RUS77261.1 - 1.5 8.5 7.6 12 5.5 0.1 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3562) rve_2 PF13333.6 RUS77261.1 - 1.6 8.9 8.8 2.1 8.6 0.5 3.8 1 1 3 4 4 4 0 Integrase core domain fn3 PF00041.21 RUS77262.1 - 2.7e-162 527.6 15.5 4.2e-21 75.1 0.1 10.5 10 0 0 10 10 10 10 Fibronectin type III domain I-set PF07679.16 RUS77262.1 - 4.5e-58 193.3 0.4 1.1e-14 54.2 0.0 7.1 8 0 0 8 8 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77262.1 - 1.3e-29 102.6 0.5 2.5e-07 31.2 0.0 6.0 5 0 0 5 5 5 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS77262.1 - 4.6e-25 88.0 10.9 0.0037 17.8 0.1 11.4 11 3 0 11 11 11 6 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 RUS77262.1 - 2e-19 69.4 0.2 0.015 15.2 0.0 9.2 9 0 0 9 9 9 4 Tissue factor Ig_2 PF13895.6 RUS77262.1 - 8.6e-15 54.8 0.0 0.041 14.2 0.0 5.0 4 0 0 4 4 4 3 Immunoglobulin domain Y_Y_Y PF07495.13 RUS77262.1 - 9.1e-12 44.8 3.0 2.4 8.2 0.0 10.1 11 0 0 11 11 11 2 Y_Y_Y domain ig PF00047.25 RUS77262.1 - 1.4e-11 44.4 0.0 0.067 13.4 0.0 4.9 4 0 0 4 4 4 3 Immunoglobulin domain fn3_2 PF16893.5 RUS77262.1 - 8.7e-11 41.8 0.0 0.23 11.6 0.0 8.0 8 0 0 8 8 8 1 Fibronectin type III domain fn3_4 PF16794.5 RUS77262.1 - 1.3e-08 34.7 0.0 1.8 8.5 0.0 8.0 9 0 0 9 9 9 2 Fibronectin-III type domain DUF11 PF01345.18 RUS77262.1 - 3.7e-07 30.3 0.8 4.8 7.5 0.0 6.7 7 0 0 7 7 6 1 Domain of unknown function DUF11 Receptor_2B4 PF11465.8 RUS77262.1 - 1.7e-05 25.0 0.0 0.12 12.6 0.0 4.4 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 RUS77262.1 - 2.9e-05 24.0 0.2 1.6 8.8 0.0 4.2 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain bMG6 PF17962.1 RUS77262.1 - 4.7e-05 23.5 2.6 15 5.7 0.0 7.2 7 0 0 7 7 7 0 Bacterial macroglobulin domain 6 DUF4959 PF16323.5 RUS77262.1 - 0.00055 20.2 0.1 12 6.2 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4959) DUF2369 PF10179.9 RUS77262.1 - 0.00075 19.8 0.0 39 4.7 0.0 5.8 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) DUF4958 PF16319.5 RUS77262.1 - 0.013 13.5 0.2 0.95 7.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4958) Tox-PLDMTX PF15645.6 RUS77262.1 - 0.022 15.0 0.0 0.76 10.0 0.0 3.2 3 1 1 4 4 4 0 Dermonecrotoxin of the Papain-like fold Kelch_1 PF01344.25 RUS77262.1 - 0.066 12.8 0.1 0.53 9.9 0.0 2.7 3 0 0 3 3 2 0 Kelch motif Big_3 PF07523.12 RUS77262.1 - 0.1 12.9 4.2 2.3 8.6 0.7 3.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Pkinase PF00069.25 RUS77263.1 - 2.4e-14 53.4 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 RUS77263.1 - 1.4e-12 47.8 0.0 3.2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pkinase_Tyr PF07714.17 RUS77263.1 - 1.5e-06 27.7 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 RUS77263.1 - 0.0018 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 RUS77263.1 - 0.046 14.3 0.0 0.18 12.4 0.0 1.9 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS77263.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 RUS77264.1 - 4.4e-101 331.2 0.0 1.9e-20 72.7 0.0 5.7 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77264.1 - 2.3e-64 214.0 1.6 2.5e-12 47.2 0.0 6.2 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 RUS77264.1 - 7.5e-44 147.8 0.3 1.2e-09 38.2 0.0 6.5 5 1 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 RUS77264.1 - 6.5e-41 138.5 1.4 1.3e-09 38.2 0.0 6.2 5 1 0 5 5 5 5 Immunoglobulin domain Pkinase PF00069.25 RUS77264.1 - 1.6e-26 93.2 0.0 2.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 RUS77264.1 - 2.2e-21 76.1 2.2 0.0063 16.7 0.0 9.2 5 5 1 6 6 6 5 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 RUS77264.1 - 6.6e-09 35.4 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_4 PF16680.5 RUS77264.1 - 4.7e-08 33.2 0.2 0.016 15.5 0.0 4.4 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 RUS77264.1 - 6e-08 33.0 0.0 0.58 10.6 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 RUS77264.1 - 3.4e-07 30.4 0.0 0.73 10.1 0.0 4.8 5 0 0 5 5 5 2 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 RUS77264.1 - 6.4e-07 29.3 0.1 0.079 13.0 0.0 4.9 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS77264.1 - 9.7e-07 29.1 0.4 2.9 8.4 0.0 5.3 5 2 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 RUS77264.1 - 8.8e-06 25.7 0.3 0.084 12.9 0.0 5.0 5 1 0 5 5 5 1 C17orf99 Ig domain Izumo-Ig PF16706.5 RUS77264.1 - 0.013 15.5 0.1 42 4.3 0.0 4.5 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain DUF481 PF04338.12 RUS77265.1 - 0.0012 19.0 4.1 0.0039 17.2 4.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF481 Gp5_C PF06715.12 RUS77265.1 - 0.0017 18.4 22.8 0.77 10.0 1.3 6.1 1 1 7 8 8 8 5 Gp5 C-terminal repeat (3 copies) Bactofilin PF04519.13 RUS77265.1 - 0.012 15.9 1.2 0.09 13.1 1.2 2.1 1 1 0 1 1 1 0 Polymer-forming cytoskeletal DUF1943 PF09172.11 RUS77265.1 - 0.12 11.6 0.9 0.15 11.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4390 PF14334.6 RUS77265.1 - 0.13 11.7 0.3 10 5.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4390) Glyco_hydro_127 PF07944.12 RUS77265.1 - 0.15 10.6 0.2 0.4 9.1 0.2 1.8 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 DUF5627 PF18620.1 RUS77265.1 - 0.44 10.4 12.8 1.5e+03 -1.0 12.8 3.4 1 1 0 1 1 1 0 Family of unknown function (DUF5627) Got1 PF04178.12 RUS77266.1 - 6.6e-19 68.4 15.1 8.7e-19 68.0 15.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Fzo_mitofusin PF04799.13 RUS77266.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region Phage_holin_3_6 PF07332.11 RUS77266.1 - 1.5 8.9 14.7 1.7 8.7 2.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RRM_1 PF00076.22 RUS77267.1 - 7.7e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RUS77267.1 - 0.0022 18.0 1.2 0.0042 17.1 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle SRP19 PF01922.17 RUS77268.1 - 4.7e-25 88.3 0.0 8.6e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Arrestin_C PF02752.22 RUS77269.1 - 3.4e-21 76.1 0.0 3.8e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RUS77269.1 - 1.1e-14 54.7 0.0 9.8e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DivIC PF04977.15 RUS77270.1 - 0.0067 16.2 0.9 0.0067 16.2 0.9 6.2 2 1 2 5 5 5 2 Septum formation initiator Leu_zip PF15294.6 RUS77270.1 - 0.0095 15.5 17.5 0.0095 15.5 17.5 3.2 1 1 2 3 3 3 1 Leucine zipper YabA PF06156.13 RUS77270.1 - 0.047 14.3 39.3 0.33 11.6 6.5 4.3 2 1 2 4 4 4 0 Initiation control protein YabA Noelin-1 PF12308.8 RUS77270.1 - 0.065 13.2 0.6 0.065 13.2 0.6 3.7 3 1 1 4 4 4 0 Neurogenesis glycoprotein TSC22 PF01166.18 RUS77270.1 - 0.32 11.4 24.8 0.29 11.5 0.8 5.2 3 3 3 6 6 6 0 TSC-22/dip/bun family Mating_N PF12731.7 RUS77270.1 - 0.39 10.8 10.2 0.69 10.0 0.4 3.2 2 1 2 4 4 4 0 Mating-type protein beta 1 Cnn_1N PF07989.11 RUS77270.1 - 0.48 10.6 41.6 0.12 12.5 12.1 4.6 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 CCDC144C PF14915.6 RUS77270.1 - 0.82 8.7 48.6 0.61 9.2 25.7 2.7 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region HAP1_N PF04849.13 RUS77270.1 - 1.1 8.4 51.4 0.36 10.0 9.8 3.9 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Spc7 PF08317.11 RUS77270.1 - 1.7 7.4 51.6 0.021 13.7 11.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 RUS77270.1 - 2.4 8.2 50.3 0.3 11.2 5.0 4.4 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 RUS77270.1 - 4.1 7.2 52.4 0.022 14.6 29.6 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 RUS77271.1 - 2.4e-05 23.4 54.7 0.0067 15.4 16.3 3.1 1 1 2 3 3 3 3 Spc7 kinetochore protein Lebercilin PF15619.6 RUS77271.1 - 5.4e-05 22.9 54.9 0.00049 19.8 30.9 3.5 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 RUS77271.1 - 0.00046 20.5 59.6 0.044 14.0 10.4 3.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 RUS77271.1 - 0.0015 19.1 49.7 0.22 11.9 6.8 3.3 1 1 2 3 3 3 2 Fez1 DUF641 PF04859.12 RUS77271.1 - 0.0041 17.5 37.8 0.1 12.9 3.1 4.6 1 1 3 4 4 4 2 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 RUS77271.1 - 0.026 13.9 35.5 0.091 12.1 19.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 RUS77271.1 - 0.029 14.5 51.9 0.4 10.8 17.3 3.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 RUS77271.1 - 0.031 14.5 41.3 0.92 9.8 2.7 5.5 3 2 0 4 4 4 0 ABC transporter C-terminal domain MscS_porin PF12795.7 RUS77271.1 - 0.035 13.6 1.3 0.035 13.6 1.3 3.3 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 RUS77271.1 - 0.066 12.7 53.3 0.42 10.1 14.7 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 RUS77271.1 - 0.067 12.8 44.8 0.27 10.8 13.0 3.9 1 1 3 4 4 4 0 Intermediate filament protein APG6_N PF17675.1 RUS77271.1 - 0.068 13.7 57.0 0.094 13.2 9.0 4.2 1 1 4 5 5 5 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 RUS77271.1 - 0.089 12.9 53.5 0.28 11.3 28.0 3.7 1 1 0 3 3 3 0 Tropomyosin like HrpB7 PF09486.10 RUS77271.1 - 0.09 13.2 39.3 0.23 11.8 14.3 4.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 RUS77271.1 - 0.1 12.6 53.3 0.062 13.3 4.3 5.4 3 2 2 6 6 6 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 RUS77271.1 - 0.14 12.2 53.4 0.35 10.9 6.3 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding HOOK PF05622.12 RUS77271.1 - 0.23 9.6 53.0 0.51 8.4 31.6 2.2 1 1 1 2 2 2 0 HOOK protein VasI PF11319.8 RUS77271.1 - 0.27 10.9 9.5 0.42 10.3 8.6 1.9 1 1 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF4201 PF13870.6 RUS77271.1 - 0.27 11.0 46.4 1.9 8.2 11.2 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) Csm1_N PF18504.1 RUS77271.1 - 0.33 11.3 55.7 0.27 11.6 0.6 7.7 4 3 3 7 7 7 0 Csm1 N-terminal domain DivIC PF04977.15 RUS77271.1 - 0.37 10.6 46.5 0.11 12.3 2.1 6.0 4 1 4 8 8 7 0 Septum formation initiator CC2-LZ PF16516.5 RUS77271.1 - 0.46 10.9 41.5 0.72 10.2 6.0 5.2 2 2 2 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2163 PF09931.9 RUS77271.1 - 0.49 10.6 7.3 0.28 11.4 3.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2163) YabA PF06156.13 RUS77271.1 - 0.6 10.8 45.1 0.072 13.7 4.3 5.1 2 2 3 5 5 5 0 Initiation control protein YabA DUF3867 PF12983.7 RUS77271.1 - 0.69 9.9 8.6 0.14 12.2 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) Tropomyosin PF00261.20 RUS77271.1 - 0.8 9.0 45.1 1.1 8.5 28.5 2.6 1 1 0 2 2 2 0 Tropomyosin EzrA PF06160.12 RUS77271.1 - 0.81 7.8 36.2 0.22 9.6 9.9 3.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FlxA PF14282.6 RUS77271.1 - 1 9.4 57.2 0.17 11.9 16.3 4.8 1 1 3 4 4 4 0 FlxA-like protein HAUS-augmin3 PF14932.6 RUS77271.1 - 1.1 8.8 44.1 0.49 9.9 37.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 LRRFIP PF09738.9 RUS77271.1 - 1.4 8.4 49.0 0.014 14.9 22.4 2.2 1 1 1 2 2 2 0 LRRFIP family BRE1 PF08647.11 RUS77271.1 - 1.5 8.9 52.8 0.75 9.9 9.9 5.1 1 1 4 5 5 5 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 RUS77271.1 - 2.8 8.6 48.8 1.1 9.9 1.8 5.6 3 2 2 5 5 5 0 SlyX DUF724 PF05266.14 RUS77271.1 - 2.8 7.7 41.6 0.78 9.5 7.3 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 RUS77271.1 - 2.9 8.1 39.2 1.3 9.2 8.4 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 RUS77271.1 - 4.1 7.8 51.1 0.75 10.2 15.2 4.2 1 1 3 4 4 4 0 Centromere protein H (CENP-H) DUF1192 PF06698.11 RUS77271.1 - 4.5 7.4 27.2 0.82 9.8 0.2 6.3 5 2 3 8 8 7 0 Protein of unknown function (DUF1192) AAA_13 PF13166.6 RUS77271.1 - 4.7 5.7 38.6 0.12 11.0 5.2 3.2 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.9 RUS77271.1 - 5.3 6.0 48.9 0.043 12.9 10.4 3.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rota_NSP4 PF01452.16 RUS77271.1 - 5.4 6.7 10.0 0.15 11.7 1.8 2.3 1 1 0 2 2 2 0 Rotavirus non structural protein DUF2730 PF10805.8 RUS77271.1 - 5.8 7.1 31.6 0.3 11.2 5.7 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.8 RUS77271.1 - 6.3 7.0 53.3 5.6 7.2 3.3 5.2 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 RUS77271.1 - 8.8 6.4 36.7 4.3 7.4 10.2 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 RUS77271.1 - 9.5 6.6 50.6 3.6 8.0 13.0 3.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region PspA_IM30 PF04012.12 RUS77271.1 - 10 5.7 49.2 5.8 6.4 21.5 3.6 1 1 2 3 3 2 0 PspA/IM30 family BRE1 PF08647.11 RUS77272.1 - 0.013 15.5 5.2 0.013 15.5 5.2 11.8 4 2 7 12 12 12 0 BRE1 E3 ubiquitin ligase FGAR-AT_linker PF18072.1 RUS77272.1 - 5 7.8 7.9 47 4.6 0.1 4.4 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Neur_chan_LBD PF02931.23 RUS77273.1 - 3.5e-11 43.0 0.1 5.6e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS77273.1 - 1.6e-06 28.4 7.5 0.00073 19.7 6.9 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF5367 PF17329.2 RUS77273.1 - 0.04 14.0 2.5 0.089 12.9 2.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5367) Peptidase_S49_N PF08496.10 RUS77273.1 - 0.082 13.0 0.2 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3278 PF11683.8 RUS77273.1 - 1.5 9.0 5.9 0.41 10.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) NADH_4Fe-4S PF10589.9 RUS77274.1 - 0.089 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF1948 PF09185.10 RUS77274.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) PLATZ PF04640.14 RUS77274.1 - 0.25 12.0 1.9 19 6.0 0.0 2.6 2 1 1 3 3 3 0 PLATZ transcription factor MORN PF02493.20 RUS77275.1 - 6.1e-06 25.8 1.4 0.0049 16.7 0.1 2.5 2 0 0 2 2 2 2 MORN repeat TFIIE-A_C PF11521.8 RUS77275.1 - 0.013 15.8 6.1 0.023 15.0 6.1 1.3 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha NOA36 PF06524.12 RUS77275.1 - 0.61 9.3 5.8 0.86 8.9 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein Adhes-Ig_like PF09085.10 RUS77275.1 - 2 8.6 3.5 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like CD45 PF12567.8 RUS77276.1 - 0.031 14.2 4.5 0.12 12.3 0.2 2.6 2 0 0 2 2 2 0 Leukocyte receptor CD45 PKcGMP_CC PF16808.5 RUS77278.1 - 1.6 8.7 3.3 1.5 8.7 1.0 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3591 PF12157.8 RUS77280.1 - 9.3e-160 532.1 0.0 9.3e-160 532.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 RUS77280.1 - 5.7e-39 132.1 5.9 2.5e-19 69.1 0.7 3.2 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 RUS77280.1 - 4.6e-09 36.0 1.1 1.5e-08 34.3 1.1 1.9 1 0 0 1 1 1 1 Zinc knuckle Baculo_8kDa PF06096.11 RUS77280.1 - 2.7 8.2 7.3 0.52 10.5 1.1 3.1 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein zf-C2H2 PF00096.26 RUS77281.1 - 1e-14 54.1 27.8 3.7e-06 27.1 3.2 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS77281.1 - 4.4e-09 36.3 1.4 4.4e-09 36.3 1.4 4.9 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS77281.1 - 1.6e-07 31.6 26.0 0.00047 20.8 2.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS77281.1 - 0.014 15.4 1.6 0.014 15.4 1.6 3.6 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS77281.1 - 0.037 14.3 0.2 0.037 14.3 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3850 PF12961.7 RUS77281.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-met PF12874.7 RUS77281.1 - 0.17 12.3 6.1 0.28 11.6 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 RUS77281.1 - 0.59 10.8 6.3 2.9 8.6 0.7 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain SAM_1 PF00536.30 RUS77282.1 - 1e-11 45.1 0.1 1.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS77282.1 - 4.6e-08 33.1 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_Tyr PF07714.17 RUS77283.1 - 1.5e-58 198.1 0.0 2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS77283.1 - 3.1e-44 151.3 0.0 3.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Cyclase_polyket PF04673.12 RUS77284.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Polyketide synthesis cyclase Zip PF02535.22 RUS77284.1 - 2.4 7.3 4.2 3.1 6.9 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neurochondrin PF05536.11 RUS77285.1 - 1.9e-30 105.8 5.8 2.5e-24 85.6 4.9 2.1 2 0 0 2 2 2 2 Neurochondrin SMYLE_N PF18615.1 RUS77286.1 - 5.1 6.5 13.8 8.3 5.9 13.8 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CSG2 PF16965.5 RUS77286.1 - 5.2 5.9 5.3 7.8 5.3 5.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator zf-RING_2 PF13639.6 RUS77288.1 - 7e-13 48.7 6.8 7e-13 48.7 6.8 2.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 RUS77288.1 - 6.1e-10 38.7 2.0 6.1e-10 38.7 2.0 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS77288.1 - 2.2e-09 37.0 7.3 2.2e-09 37.0 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS77288.1 - 7.4e-08 32.6 4.3 7.4e-08 32.6 4.3 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS77288.1 - 1e-07 31.7 4.5 2.8e-07 30.3 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS77288.1 - 1.9e-07 30.9 3.3 4.9e-07 29.6 3.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 RUS77288.1 - 8.8e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 RUS77288.1 - 9.1e-06 25.6 4.3 9.1e-06 25.6 4.3 2.0 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS77288.1 - 1.9e-05 24.4 4.6 3.9e-05 23.4 4.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RUS77288.1 - 5.9e-05 22.9 3.0 0.00012 21.9 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS77288.1 - 0.0053 16.8 2.8 0.0053 16.8 2.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RUS77288.1 - 0.0061 16.2 2.9 0.0061 16.2 2.9 2.9 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type EMP24_GP25L PF01105.24 RUS77288.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PHD PF00628.29 RUS77288.1 - 0.36 10.8 6.5 0.37 10.7 4.7 2.1 2 0 0 2 2 1 0 PHD-finger RINGv PF12906.7 RUS77288.1 - 1.2 9.3 4.4 3.5 7.8 4.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 RUS77288.1 - 9.1 6.4 11.4 0.98 9.5 4.2 2.5 2 0 0 2 2 2 0 Zinc-finger zf-RING_2 PF13639.6 RUS77289.1 - 1.9e-13 50.5 7.2 1.9e-13 50.5 7.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 RUS77289.1 - 6.5e-10 38.6 7.2 1.5e-09 37.5 3.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS77289.1 - 2.9e-09 36.6 7.5 2.9e-09 36.6 7.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS77289.1 - 8.3e-08 32.0 5.3 1.7e-07 31.0 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS77289.1 - 3.5e-07 30.1 3.5 1e-06 28.6 3.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS77289.1 - 9.9e-07 29.0 7.7 9.9e-07 29.0 7.7 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS77289.1 - 4.7e-06 26.5 4.7 4.7e-06 26.5 4.7 1.8 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS77289.1 - 5e-05 23.1 4.8 0.00012 21.8 4.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RUS77289.1 - 5.1e-05 23.1 3.1 0.00011 22.0 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS77289.1 - 0.0013 18.7 2.3 0.003 17.6 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.12 RUS77289.1 - 0.017 15.1 0.5 0.046 13.8 0.2 1.8 2 0 0 2 2 2 0 Phage shock protein B Zn_ribbon_17 PF17120.5 RUS77289.1 - 0.02 14.5 9.7 0.021 14.4 4.3 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 RUS77289.1 - 0.061 13.2 4.3 0.18 11.7 4.3 1.9 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 RUS77289.1 - 0.55 10.4 5.4 1.1 9.4 4.7 1.9 2 0 0 2 2 1 0 RING-variant domain zf-C3H2C3 PF17122.5 RUS77289.1 - 9.7 6.3 11.3 0.99 9.5 4.2 2.6 2 0 0 2 2 2 0 Zinc-finger MFS_1_like PF12832.7 RUS77290.1 - 1.1e-86 291.1 17.7 1.4e-86 290.8 17.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RUS77290.1 - 1.6e-19 70.0 41.4 2e-08 33.6 1.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RUS77290.1 - 7e-16 58.2 27.2 3e-14 52.8 22.8 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 RUS77290.1 - 1.8e-07 30.3 29.0 0.0021 16.9 17.4 3.2 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 RUS77290.1 - 3.9 5.8 14.2 0.75 8.1 6.1 2.6 2 1 0 2 2 2 0 Transmembrane secretion effector VMA21 PF09446.10 RUS77291.1 - 1.1e-19 70.3 13.8 1.2e-19 70.1 13.8 1.0 1 0 0 1 1 1 1 VMA21-like domain PMP22_Claudin PF00822.20 RUS77291.1 - 0.023 14.6 1.9 0.022 14.6 1.9 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1691 PF07950.11 RUS77291.1 - 0.29 11.9 2.1 0.4 11.4 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) SPC25 PF06703.11 RUS77291.1 - 4.4 7.1 5.9 30 4.3 5.9 1.9 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UPF0506 PF11703.8 RUS77292.1 - 0.019 15.4 4.0 0.035 14.5 4.0 1.4 1 1 0 1 1 1 0 UPF0506 Defensin_beta PF00711.19 RUS77293.1 - 1.4 9.0 10.4 1.2 9.2 2.5 2.3 1 1 1 2 2 2 0 Beta defensin MFS_1 PF07690.16 RUS77294.1 - 4.3e-37 127.9 22.0 5.3e-28 98.0 2.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS77294.1 - 1.7e-08 33.8 0.0 0.0013 17.7 0.0 2.2 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 RUS77295.1 - 2.1e-22 79.6 11.5 6e-13 48.4 0.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 RUS77296.1 - 1e-43 146.4 25.2 1.2e-09 38.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77296.1 - 5.9e-20 71.4 0.0 4.9e-05 23.5 0.0 5.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS77296.1 - 4.5e-06 25.9 5.0 0.78 8.6 0.5 4.7 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RUS77296.1 - 0.0011 17.6 0.0 0.049 12.1 0.0 2.4 1 1 3 4 4 4 3 Cytochrome D1 heme domain WD40_like PF17005.5 RUS77296.1 - 0.0013 18.2 0.2 4.9 6.4 0.1 3.1 2 1 1 3 3 3 3 WD40-like domain PD40 PF07676.12 RUS77296.1 - 0.0052 16.7 0.5 7.1 6.7 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 RUS77296.1 - 0.011 14.4 0.1 0.048 12.3 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RUS77296.1 - 0.064 12.0 0.2 0.69 8.6 0.0 2.5 1 1 1 3 3 3 0 Nup133 N terminal like PHTB1_N PF14727.6 RUS77296.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 PTHB1 N-terminus Ras PF00071.22 RUS77297.1 - 9.3e-33 113.1 0.1 5.4e-25 87.9 0.1 3.1 2 1 1 3 3 3 3 Ras family Roc PF08477.13 RUS77297.1 - 2.8e-19 69.5 0.2 3.4e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS77297.1 - 3.3e-09 36.4 0.1 3.7e-06 26.5 0.2 3.0 1 1 2 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS77297.1 - 0.00041 19.9 0.3 0.032 13.8 0.1 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS77297.1 - 0.00051 20.1 0.0 0.00097 19.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS77297.1 - 0.00069 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 RUS77297.1 - 0.066 12.9 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RUS77297.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS77297.1 - 0.085 13.1 0.0 0.29 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF418 PF04235.12 RUS77298.1 - 0.00023 21.1 4.4 3.2 7.7 0.1 3.8 1 1 4 5 5 5 4 Protein of unknown function (DUF418) NtCtMGAM_N PF16863.5 RUS77298.1 - 0.029 14.6 4.0 1.4 9.1 1.2 2.6 1 1 1 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Cuticle_3 PF11018.8 RUS77298.1 - 0.035 14.3 0.7 0.074 13.3 0.7 1.5 1 1 0 1 1 1 0 Pupal cuticle protein C1 LPD34 PF18852.1 RUS77298.1 - 0.12 12.0 2.9 0.98 9.0 0.3 2.5 1 1 1 2 2 2 0 Large polyvalent protein associated domain 34 DUF1758 PF05585.12 RUS77298.1 - 0.3 10.9 4.4 3.3 7.4 0.5 2.2 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Exog_C PF18026.1 RUS77298.1 - 0.6 10.2 13.4 2.8e+02 1.6 0.1 7.5 1 1 7 8 8 8 0 Endo/exonuclease (EXOG) C-terminal domain CDO_I PF05995.12 RUS77299.1 - 1.4e-55 187.2 0.2 4e-55 185.7 0.2 1.6 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 RUS77299.1 - 0.00026 20.5 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO DUF2798 PF11391.8 RUS77300.1 - 9.2e-05 22.4 57.3 0.23 11.5 7.3 5.3 1 1 2 3 3 3 1 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RUS77300.1 - 0.15 12.1 22.5 19 5.4 4.5 4.6 2 2 0 2 2 2 0 Glycine zipper DUF5455 PF17537.2 RUS77300.1 - 2.2 8.7 28.6 1.1e+03 0.0 10.1 5.6 2 2 0 2 2 2 0 Family of unknown function (DUF5455) Romo1 PF10247.9 RUS77300.1 - 3.7 8.0 27.1 4.4 7.7 2.2 5.5 3 2 1 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Peptidase_C1 PF00112.23 RUS77301.1 - 5.1e-26 92.1 0.1 1.3e-25 90.8 0.0 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RUS77301.1 - 6.6e-13 48.9 3.2 1.1e-12 48.2 3.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ASFV_J13L PF05568.11 RUS77302.1 - 0.0022 17.7 0.3 0.7 9.6 0.1 2.4 1 1 1 2 2 2 2 African swine fever virus J13L protein zf-CRD PF17979.1 RUS77302.1 - 0.37 10.9 10.9 2 8.5 3.1 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Peptidase_C1 PF00112.23 RUS77303.1 - 2.2e-33 116.2 0.3 2.3e-33 116.1 0.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RUS77303.1 - 0.00012 21.0 0.5 0.00014 20.8 0.5 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 RUS77304.1 - 2e-62 211.1 6.9 2e-62 211.1 6.9 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RUS77304.1 - 1.9e-11 44.2 4.9 3.4e-11 43.4 4.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3176 PF11374.8 RUS77304.1 - 0.014 15.6 0.1 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) RT_RNaseH_2 PF17919.1 RUS77305.1 - 6.8e-34 115.9 0.0 2.2e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS77305.1 - 1.7e-33 115.0 0.0 5e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77305.1 - 6.4e-21 74.9 0.0 9.5e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GREB1 PF15782.5 RUS77306.1 - 4.6 4.2 30.3 7.2 3.6 30.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FERM_f0 PF16511.5 RUS77307.1 - 1.4e-39 134.2 0.1 3.6e-36 123.3 0.0 3.2 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 RUS77307.1 - 2.3e-27 95.8 0.0 4.9e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS77307.1 - 9.6e-22 76.7 0.2 1.3e-17 63.5 0.5 3.0 2 0 0 2 2 2 2 FERM N-terminal domain Talin_middle PF09141.10 RUS77307.1 - 4.4e-07 30.1 0.0 9.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Talin, middle domain IRS PF02174.17 RUS77307.1 - 6.4e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DUF1013 PF06242.11 RUS77307.1 - 0.0015 18.5 0.2 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1013) Ribosomal_S17e PF00833.18 RUS77307.1 - 0.054 13.4 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 Ribosomal S17 I_LWEQ PF01608.17 RUS77308.1 - 2.9e-21 76.3 77.0 1.7e-05 25.1 7.5 8.1 3 2 6 9 9 9 9 I/LWEQ domain Vinculin PF01044.19 RUS77308.1 - 0.00033 19.1 43.0 0.014 13.7 0.3 4.6 1 1 3 4 4 4 4 Vinculin family VBS PF08913.10 RUS77308.1 - 0.0012 19.3 1.8 0.0012 19.3 1.8 5.8 3 1 0 5 5 5 2 Vinculin Binding Site TetR_C_30 PF17939.1 RUS77308.1 - 0.012 15.8 0.1 0.054 13.7 0.1 2.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Thiamine_BP PF01910.17 RUS77308.1 - 0.025 14.5 2.4 1.5 8.8 0.2 3.6 3 1 0 3 3 3 0 Thiamine-binding protein YscK PF06578.12 RUS77308.1 - 0.054 13.0 1.4 0.11 12.0 0.4 2.0 2 0 0 2 2 2 0 YOP proteins translocation protein K (YscK) FliS_cochap PF16522.5 RUS77308.1 - 0.31 11.0 0.0 0.31 11.0 0.0 3.6 4 1 0 4 4 4 0 Flagellar FLiS export co-chaperone, HP1076 Syntaxin-6_N PF09177.11 RUS77308.1 - 3.6 8.2 27.8 0.38 11.4 0.9 6.5 2 2 4 6 6 6 0 Syntaxin 6, N-terminal Focal_AT PF03623.13 RUS77308.1 - 3.9 7.5 21.2 1.7 8.6 1.7 5.9 1 1 3 7 7 7 0 Focal adhesion targeting region PsbX PF06596.11 RUS77309.1 - 9.3e-07 28.8 0.0 1.7e+02 2.3 0.0 9.5 14 0 0 14 14 14 0 Photosystem II reaction centre X protein (PsbX) FtsK_SpoIIIE_N PF12538.8 RUS77309.1 - 9.9e-06 25.8 1.5 6.1 7.1 0.0 4.8 1 1 5 6 6 6 4 DNA transporter FERM_f0 PF16511.5 RUS77309.1 - 0.0093 16.3 10.4 12 6.3 0.2 4.1 1 1 2 4 4 4 2 N-terminal or F0 domain of Talin-head FERM LpxK PF02606.14 RUS77309.1 - 0.06 12.4 0.6 10 5.1 0.1 3.3 1 1 2 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase DUF2344 PF10105.9 RUS77309.1 - 0.21 11.4 19.4 44 3.9 0.2 7.2 1 1 6 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF1891 PF09004.10 RUS77309.1 - 0.26 10.9 17.5 16 5.2 0.0 7.1 1 1 8 10 10 10 0 Domain of unknown function (DUF1891) I_LWEQ PF01608.17 RUS77310.1 - 5.2e-08 33.3 19.9 1.4e-06 28.6 10.6 3.5 1 1 2 3 3 3 2 I/LWEQ domain VBS PF08913.10 RUS77310.1 - 9.3e-05 22.9 11.6 0.69 10.4 0.2 3.2 2 1 1 3 3 3 3 Vinculin Binding Site Focal_AT PF03623.13 RUS77310.1 - 0.0082 16.1 9.6 2.6 8.1 1.2 4.2 2 2 1 3 3 3 3 Focal adhesion targeting region DUF3022 PF11226.8 RUS77310.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Rx_N PF18052.1 RUS77310.1 - 0.038 14.3 0.9 0.089 13.1 0.5 1.8 2 0 0 2 2 2 0 Rx N-terminal domain Synuclein PF01387.17 RUS77310.1 - 0.071 13.3 3.3 0.065 13.4 0.8 2.1 2 0 0 2 2 2 0 Synuclein DUF2573 PF10835.8 RUS77310.1 - 0.097 13.0 0.7 43 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2573) Syntaxin-18_N PF10496.9 RUS77310.1 - 0.1 12.8 3.3 0.68 10.2 0.3 3.1 2 2 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus SMBP PF16785.5 RUS77310.1 - 0.11 12.7 13.3 0.12 12.6 1.0 3.4 1 1 2 3 3 3 0 Small metal-binding protein Fes1 PF08609.10 RUS77310.1 - 0.18 12.7 4.8 0.43 11.5 0.3 2.9 2 2 0 2 2 2 0 Nucleotide exchange factor Fes1 GIT1_C PF12205.8 RUS77310.1 - 0.31 11.2 18.2 0.45 10.6 0.1 3.7 1 1 2 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term HisKA PF00512.25 RUS77310.1 - 0.32 11.1 1.7 2.9 8.0 1.3 2.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain FIVAR PF07554.13 RUS77310.1 - 0.45 11.3 10.4 15 6.4 1.6 4.0 4 1 0 4 4 4 0 FIVAR domain DUF1657 PF07870.11 RUS77310.1 - 0.82 9.6 4.2 0.88 9.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) LOH1CR12 PF10158.9 RUS77310.1 - 2.2 8.3 9.8 0.36 10.9 0.3 3.5 1 1 2 4 4 4 0 Tumour suppressor protein GldM_N PF12081.8 RUS77310.1 - 2.8 8.0 7.3 26 4.8 7.0 2.6 1 1 0 1 1 1 0 GldM N-terminal domain VBS PF08913.10 RUS77311.1 - 0.00035 21.0 0.3 0.00084 19.8 0.1 1.7 2 0 0 2 2 2 1 Vinculin Binding Site Laminin_II PF06009.12 RUS77311.1 - 0.038 14.0 0.1 0.053 13.5 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DbpA PF03880.15 RUS77311.1 - 0.083 12.9 0.1 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 DbpA RNA binding domain DUF2277 PF10041.9 RUS77311.1 - 0.091 13.1 0.1 0.35 11.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) Fib_alpha PF08702.10 RUS77311.1 - 0.12 12.6 0.2 0.13 12.5 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family I_LWEQ PF01608.17 RUS77312.1 - 2.7e-43 147.8 47.7 1.3e-41 142.4 11.2 4.9 2 1 3 5 5 5 5 I/LWEQ domain T4_Gp59_C PF08994.10 RUS77313.1 - 0.00036 21.1 6.6 14 6.3 0.1 5.1 1 1 6 7 7 7 2 T4 gene Gp59 loader of gp41 DNA helicase C-term CRM1_repeat PF18777.1 RUS77313.1 - 0.00037 19.9 10.1 46 3.6 0.0 6.7 1 1 6 7 7 7 0 Chromosome region maintenance or exportin repeat CLASP_N PF12348.8 RUS77313.1 - 0.00089 18.9 0.2 7.1 6.1 0.0 3.5 1 1 3 4 4 4 2 CLASP N terminal DUF2171 PF09939.9 RUS77313.1 - 0.0064 16.7 0.1 18 5.7 0.0 3.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2171) ODC_AZ PF02100.17 RUS77313.1 - 0.066 13.2 3.5 0.9 9.5 0.6 2.4 1 1 1 2 2 2 0 Ornithine decarboxylase antizyme TerB PF05099.13 RUS77313.1 - 0.069 13.1 5.5 1 9.3 0.8 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB TcA_RBD PF18518.1 RUS77313.1 - 0.076 13.3 0.8 3.5 7.9 0.2 2.1 1 1 1 2 2 2 0 TcA receptor binding domain A2M_recep PF07677.14 RUS77313.1 - 0.24 12.1 0.9 21 5.9 0.3 2.9 1 1 1 2 2 2 0 A-macroglobulin receptor binding domain PSCyt1 PF07635.11 RUS77315.1 - 0.18 12.4 0.2 0.33 11.6 0.2 1.5 1 0 0 1 1 1 0 Planctomycete cytochrome C MEF2_binding PF09047.10 RUS77316.1 - 0.0016 18.3 0.2 0.0033 17.2 0.2 1.6 1 0 0 1 1 1 1 MEF2 binding DNA_pol_phi PF04931.13 RUS77316.1 - 0.44 8.6 53.3 0.0068 14.6 36.9 2.3 2 0 0 2 2 2 0 DNA polymerase phi GKAP PF03359.13 RUS77317.1 - 1.1e-45 156.8 0.4 1.5e-45 156.3 0.4 1.2 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Med3 PF11593.8 RUS77317.1 - 3.7 6.6 13.3 0.081 12.1 6.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2477 PF10631.9 RUS77317.1 - 8.6 7.0 8.4 0.71 10.5 2.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2477) Zip PF02535.22 RUS77318.1 - 3.1e-28 99.0 1.0 3.8e-28 98.7 1.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RVT_1 PF00078.27 RUS77320.1 - 3.3e-10 39.9 0.1 2.8e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F5_F8_type_C PF00754.25 RUS77321.1 - 0.0018 18.4 0.0 0.0045 17.1 0.0 1.6 2 0 0 2 2 2 1 F5/8 type C domain PAZ PF02170.22 RUS77321.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 PAZ domain Na_sulph_symp PF00939.19 RUS77322.1 - 1.4e-84 284.8 30.8 8.5e-48 163.6 6.4 3.0 1 1 2 3 3 3 3 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS77322.1 - 9.1e-47 159.7 36.2 3.7e-26 92.0 1.9 3.3 1 1 2 3 3 3 3 Citrate transporter HLH PF00010.26 RUS77323.1 - 2.3e-13 49.9 0.2 6.7e-13 48.4 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Syntaxin PF00804.25 RUS77323.1 - 0.0032 17.2 0.4 0.006 16.3 0.4 1.3 1 0 0 1 1 1 1 Syntaxin DHC_N1 PF08385.12 RUS77325.1 - 1.8e-156 522.1 12.6 1.8e-156 522.1 12.6 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RUS77325.1 - 1.2e-153 510.8 0.0 8.7e-153 508.0 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS77325.1 - 3.6e-116 388.6 10.5 3.6e-116 388.6 10.5 5.1 4 3 1 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RUS77325.1 - 3.2e-98 328.2 0.0 7.8e-98 326.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RUS77325.1 - 7e-88 293.4 2.8 7e-86 286.9 1.4 3.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RUS77325.1 - 6.8e-77 257.1 3.4 1.3e-71 239.9 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 RUS77325.1 - 1.9e-62 211.2 0.1 1.5e-61 208.3 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RUS77325.1 - 8.6e-56 188.3 0.2 2.6e-55 186.7 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RUS77325.1 - 2.4e-49 168.2 14.0 2.4e-49 168.2 14.0 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS77325.1 - 3.1e-44 149.9 0.0 3.1e-43 146.7 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RUS77325.1 - 4.3e-24 85.0 0.0 2.1e-23 82.8 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS77325.1 - 2.1e-23 82.8 0.7 4.1e-06 26.8 0.0 5.7 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RUS77325.1 - 1.3e-15 57.4 2.7 3e-15 56.2 0.0 3.2 3 0 0 3 3 1 1 AAA+ lid domain AAA_22 PF13401.6 RUS77325.1 - 1.1e-09 38.6 0.3 0.081 13.2 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 RUS77325.1 - 1.7e-06 28.5 0.0 1.7 9.1 0.0 5.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS77325.1 - 1.7e-05 25.3 7.0 3.5 8.0 0.0 7.4 8 0 0 8 8 7 1 AAA ATPase domain AAA_18 PF13238.6 RUS77325.1 - 0.00044 20.8 0.0 0.19 12.3 0.0 4.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 RUS77325.1 - 0.0017 18.3 1.5 0.06 13.2 0.1 3.8 4 0 0 4 4 4 1 RsgA GTPase RNA_helicase PF00910.22 RUS77325.1 - 0.004 17.5 0.2 6.3 7.2 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 RUS77325.1 - 0.0064 16.2 3.1 2 8.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.7 RUS77325.1 - 0.0072 15.3 1.9 0.016 14.2 0.0 2.6 3 0 0 3 3 2 1 AAA-like domain Sigma54_activat PF00158.26 RUS77325.1 - 0.019 14.7 0.1 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Plasmid_RAQPRD PF09686.10 RUS77325.1 - 0.022 14.9 4.9 0.34 11.2 0.0 5.0 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) T2SSE PF00437.20 RUS77325.1 - 0.06 12.4 0.1 3.5 6.6 0.1 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 RUS77325.1 - 0.2 11.4 0.1 2.7 7.8 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RUS77325.1 - 0.2 12.2 8.7 2.1 8.9 0.2 5.0 5 0 0 5 5 4 0 ABC transporter ATPase_2 PF01637.18 RUS77325.1 - 0.37 10.7 10.4 1.5 8.6 0.4 4.9 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea Fungal_TACC PF12709.7 RUS77325.1 - 0.37 11.3 5.5 3 8.3 5.5 2.7 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF948 PF06103.11 RUS77325.1 - 1.6 9.1 12.8 69 3.8 0.1 7.9 10 0 0 10 10 5 0 Bacterial protein of unknown function (DUF948) AcylCoA_dehyd_C PF12186.8 RUS77325.1 - 2.6 8.2 7.0 36 4.5 0.2 4.2 4 0 0 4 4 3 0 Acyl-CoA dehydrogenase C terminal EI24 PF07264.11 RUS77325.1 - 4.8 7.4 7.8 13 6.0 7.8 1.6 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Macoilin PF09726.9 RUS77326.1 - 3.7 6.0 12.4 4.7 5.7 12.4 1.1 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 RUS77327.1 - 1 9.8 7.7 1.5 9.3 7.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NST1 PF13945.6 RUS77328.1 - 0.43 10.7 14.5 0.62 10.1 14.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Orf78 PF06024.12 RUS77328.1 - 1.3 9.4 5.0 2.2 8.6 5.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DNA_pol_phi PF04931.13 RUS77329.1 - 0.0026 16.0 42.3 0.0027 15.9 42.3 1.0 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 RUS77329.1 - 0.038 12.3 23.0 0.045 12.0 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS77329.1 - 0.091 11.0 29.7 0.096 10.9 29.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS77329.1 - 0.21 10.9 21.9 0.22 10.9 21.9 1.1 1 0 0 1 1 1 0 BUD22 NAM-associated PF14303.6 RUS77329.1 - 0.24 12.1 2.9 0.26 12.0 2.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Mpp10 PF04006.12 RUS77329.1 - 2.9 6.2 24.3 3.1 6.1 24.3 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF1143 PF06608.11 RUS77330.1 - 0.002 18.2 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) MRP-S22 PF10245.9 RUS77331.1 - 1.1e-91 306.9 0.0 1.3e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Ski_Sno PF02437.17 RUS77332.1 - 1.7e-40 137.1 0.6 3.7e-40 136.0 0.6 1.6 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 RUS77332.1 - 1.3e-37 127.9 1.9 3.4e-37 126.5 1.9 1.8 1 0 0 1 1 1 1 c-SKI Smad4 binding domain ZapB PF06005.12 RUS77332.1 - 0.007 16.8 4.1 0.02 15.3 4.1 1.9 1 0 0 1 1 1 1 Cell division protein ZapB KASH_CCD PF14662.6 RUS77332.1 - 0.0091 15.8 2.9 0.017 14.9 2.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH PspA_IM30 PF04012.12 RUS77332.1 - 0.019 14.6 7.5 0.038 13.5 7.5 1.4 1 0 0 1 1 1 0 PspA/IM30 family PT PF04886.12 RUS77335.1 - 5.9e-52 172.9 155.0 1.8e+04 -63.0 155.0 5.1 1 1 0 1 1 1 0 PT repeat 7TM_GPCR_Srw PF10324.9 RUS77336.1 - 7.1e-12 45.2 17.2 1.3e-11 44.4 17.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS77336.1 - 3.8e-10 39.8 16.7 3.8e-10 39.8 16.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS77336.1 - 9.5e-09 35.0 14.9 1.6e-08 34.2 14.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PXPV PF12778.7 RUS77336.1 - 0.34 10.8 1.4 20 5.2 0.1 2.4 1 1 1 2 2 2 0 PXPV repeat (3 copies) zf-RING_6 PF14835.6 RUS77336.1 - 0.38 10.7 3.8 0.34 10.8 0.8 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein cNMP_binding PF00027.29 RUS77337.1 - 2.2e-18 66.1 0.0 4.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RUS77337.1 - 6.1e-18 64.9 7.3 9.4e-18 64.3 7.3 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3987 PF13148.6 RUS77337.1 - 0.056 12.5 2.1 0.097 11.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tim54 PF11711.8 RUS77338.1 - 0.066 12.0 17.8 0.17 10.6 17.8 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vac14_Fig4_bd PF11916.8 RUS77339.1 - 3.7e-73 245.0 9.9 3.7e-73 245.0 9.9 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 RUS77339.1 - 1.9e-44 150.2 0.1 3.1e-38 130.3 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RUS77339.1 - 3.6e-07 30.5 0.3 1.2 9.7 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 RUS77339.1 - 2e-06 27.5 1.4 0.79 10.1 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat V-ATPase_H_C PF11698.8 RUS77339.1 - 0.035 14.2 0.8 5.8 7.1 0.0 3.9 3 1 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 RUS77339.1 - 0.11 12.5 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 RUS77339.1 - 0.25 11.8 1.3 13 6.2 0.0 4.1 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasome PF00227.26 RUS77340.1 - 1.1e-48 165.2 0.2 1.4e-48 165.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Ank_4 PF13637.6 RUS77342.1 - 2.3e-29 101.4 7.5 1.5e-11 44.5 0.4 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS77342.1 - 3.1e-26 91.8 2.9 3.8e-13 49.8 0.7 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS77342.1 - 8.9e-25 86.4 7.6 2.2e-08 34.2 1.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS77342.1 - 2.5e-20 70.4 4.0 0.00017 21.8 0.2 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RUS77342.1 - 3.5e-17 62.0 10.9 4.6e-05 23.7 0.6 4.7 4 0 0 4 4 4 4 Ankyrin repeat DDE_3 PF13358.6 RUS77343.1 - 0.0047 16.7 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_2 PF07719.17 RUS77345.1 - 1.6e-33 112.1 5.5 6.7e-05 22.7 0.0 9.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 RUS77345.1 - 1.9e-32 109.7 5.2 2.8e-05 23.7 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 RUS77345.1 - 7e-32 107.0 3.7 0.0011 19.0 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77345.1 - 1e-22 79.5 8.8 7.6e-05 22.3 0.0 8.2 6 2 3 9 9 9 4 TPR repeat TPR_19 PF14559.6 RUS77345.1 - 2.8e-20 72.6 1.8 2.6e-05 24.6 0.0 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 RUS77345.1 - 1.1e-17 64.1 11.2 0.00072 19.8 0.2 6.5 6 2 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS77345.1 - 8.6e-17 59.9 6.3 0.00075 19.4 0.0 9.0 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS77345.1 - 4e-15 55.7 0.0 2e-05 24.7 0.0 4.8 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS77345.1 - 1.2e-14 53.5 13.6 0.011 16.1 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS77345.1 - 7.3e-14 52.1 0.0 0.012 16.3 0.0 6.0 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RUS77345.1 - 2.2e-13 49.8 1.3 0.1 13.4 0.0 7.2 2 2 5 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS77345.1 - 1.6e-10 41.1 15.6 0.034 14.3 0.1 6.1 2 2 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RUS77345.1 - 2.8e-07 30.1 3.0 0.0039 16.4 0.2 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS77345.1 - 9.6e-07 29.1 8.7 3.5 8.5 0.0 7.4 8 0 0 8 8 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 RUS77345.1 - 1.7e-06 27.7 5.7 0.021 14.2 0.2 3.5 3 1 0 3 3 3 2 Coatomer epsilon subunit TPR_10 PF13374.6 RUS77345.1 - 2.7e-06 27.1 11.9 0.19 11.6 0.0 6.6 6 1 1 8 8 8 2 Tetratricopeptide repeat NARP1 PF12569.8 RUS77345.1 - 4.4e-06 25.9 1.1 0.0025 16.8 0.0 2.8 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 RUS77345.1 - 0.00064 20.0 0.8 0.039 14.3 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 RUS77345.1 - 0.0097 14.7 0.5 1.4 7.6 0.0 2.5 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat DUF2989 PF11207.8 RUS77345.1 - 0.093 12.5 2.5 0.76 9.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2989) ChAPs PF09295.10 RUS77345.1 - 0.12 11.4 1.9 1.1 8.2 0.4 2.7 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 RUS77345.1 - 0.13 11.9 0.4 17 5.0 0.0 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.12 RUS77345.1 - 0.34 10.9 2.0 20 5.2 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF627) DUF4638 PF15472.6 RUS77346.1 - 1e-09 38.5 0.3 1.6e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) Nnf1 PF03980.14 RUS77346.1 - 0.022 15.1 0.3 0.037 14.4 0.3 1.5 1 0 0 1 1 1 0 Nnf1 CUE PF02845.16 RUS77348.1 - 0.0028 17.3 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 CUE domain Kinesin_assoc PF16183.5 RUS77348.1 - 1.3 9.2 4.5 2.1 8.5 3.9 1.8 1 1 0 1 1 1 0 Kinesin-associated Sec34 PF04136.15 RUS77349.1 - 5.8e-50 169.0 6.9 5.8e-50 169.0 6.9 2.1 2 0 0 2 2 2 1 Sec34-like family COX17 PF05051.13 RUS77349.1 - 0.065 13.6 2.8 0.74 10.2 0.3 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) EMP24_GP25L PF01105.24 RUS77349.1 - 0.076 13.0 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.16 RUS77349.1 - 0.083 11.8 0.7 0.15 11.0 0.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_8 PF15909.5 RUS77349.1 - 0.085 13.2 0.1 0.46 10.8 0.1 2.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon UPF0203 PF05254.12 RUS77349.1 - 0.46 10.8 2.7 1.3 9.3 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) SKA2 PF16740.5 RUS77349.1 - 0.53 10.1 5.8 0.2 11.4 0.3 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Mod_r PF07200.13 RUS77349.1 - 4.1 7.5 12.4 0.36 10.9 5.5 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein zf-H2C2_5 PF13909.6 RUS77350.1 - 9.2e-15 54.1 19.7 1.3e-07 31.2 1.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RUS77350.1 - 2.7e-13 49.5 27.4 0.00057 20.2 2.0 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77350.1 - 2.5e-07 31.0 25.3 0.017 15.9 0.7 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS77350.1 - 2.6e-06 27.6 23.9 5.1e-05 23.5 0.4 5.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 RUS77350.1 - 1.7 9.2 13.8 8.3 7.0 1.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type NOA36 PF06524.12 RUS77351.1 - 0.17 11.2 35.3 0.4 10.0 35.3 1.6 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS77351.1 - 4 5.4 42.7 5.2 5.1 42.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS77351.1 - 8 4.5 27.7 13 3.8 27.7 1.3 1 0 0 1 1 1 0 Nop14-like family DHR-2 PF06920.13 RUS77352.1 - 2.8e-171 570.8 0.6 9.7e-171 569.0 0.6 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 RUS77352.1 - 1.7e-37 129.2 0.2 1.1e-28 100.4 0.0 4.0 3 1 1 4 4 4 2 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 RUS77352.1 - 3.7e-34 117.5 0.1 1.3e-33 115.8 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 RUS77352.1 - 9.9e-16 58.2 0.5 7.3e-15 55.4 0.2 2.7 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 RUS77352.1 - 0.00046 20.5 0.2 0.0064 16.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 RUS77352.1 - 0.011 16.0 0.1 0.052 13.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_17 PF18012.1 RUS77352.1 - 0.064 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 PH domain Glypican PF01153.19 RUS77353.1 - 7e-83 279.3 7.7 6.3e-45 154.0 0.6 2.2 1 1 0 2 2 2 2 Glypican RecR PF02132.15 RUS77353.1 - 0.066 12.8 2.1 0.16 11.6 2.1 1.6 1 0 0 1 1 1 0 RecR protein SWIRM-assoc_2 PF16496.5 RUS77353.1 - 0.21 10.4 2.1 0.18 10.6 1.1 1.4 1 1 0 1 1 1 0 SWIRM-associated domain at the N-terminal Bromodomain PF00439.25 RUS77354.1 - 3e-24 84.9 0.6 3.8e-24 84.6 0.6 1.1 1 0 0 1 1 1 1 Bromodomain MSA-2c PF12238.8 RUS77354.1 - 0.018 15.1 0.8 0.022 14.7 0.8 1.3 1 1 0 1 1 1 0 Merozoite surface antigen 2c zf-CCHC PF00098.23 RUS77355.1 - 3.4e-05 23.7 1.4 5.2e-05 23.1 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle Helicase_C PF00271.31 RUS77355.1 - 0.0055 17.0 0.1 0.013 15.9 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C2H2_10 PF16588.5 RUS77355.1 - 0.0089 15.7 0.6 0.014 15.1 0.6 1.2 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 RUS77355.1 - 0.027 14.2 0.6 0.04 13.6 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 RUS77355.1 - 0.038 13.8 0.3 0.06 13.2 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 RUS77355.1 - 0.26 11.2 1.7 0.49 10.3 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle CAP PF00188.26 RUS77356.1 - 4.8e-13 50.1 2.3 6.2e-13 49.7 2.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.32 RUS77357.1 - 0.00086 20.1 14.5 1.6 9.7 0.1 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 RUS77357.1 - 0.033 13.5 0.4 2.8 7.2 0.1 3.4 3 1 0 3 3 3 0 WD40-like domain ATG2_CAD PF13329.6 RUS77357.1 - 0.054 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif CAP PF00188.26 RUS77358.1 - 0.023 15.5 4.3 0.082 13.7 4.3 1.8 1 1 0 1 1 1 0 Cysteine-rich secretory protein family zf-H2C2 PF09337.10 RUS77359.1 - 0.059 13.6 5.4 1.5e+02 2.7 0.1 5.1 3 2 6 9 9 9 0 H2C2 zinc finger DUF4680 PF15730.5 RUS77359.1 - 0.25 11.7 27.2 10 6.5 0.2 6.2 1 1 9 10 10 10 0 Domain of unknown function (DUF4680) DUF3189 PF11385.8 RUS77359.1 - 2.8 7.8 4.9 25 4.7 0.2 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3189) DUF3318 PF11780.8 RUS77359.1 - 4.9 7.1 20.7 12 5.8 5.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) WD40 PF00400.32 RUS77360.1 - 3.2e-15 56.3 11.0 0.032 15.1 0.2 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF4062 PF13271.6 RUS77360.1 - 7.2e-14 51.9 0.1 1.3e-12 47.9 0.0 2.9 3 0 0 3 3 2 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.7 RUS77360.1 - 6.5e-10 39.2 5.5 1.9e-05 24.9 0.0 6.0 7 1 0 7 7 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 RUS77360.1 - 3.3e-09 36.9 0.0 7.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RUS77360.1 - 7.6e-07 29.7 0.7 7.1e-05 23.3 0.7 2.9 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 RUS77360.1 - 0.00022 21.2 0.0 0.00094 19.2 0.0 2.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PQQ_2 PF13360.6 RUS77360.1 - 0.00045 19.9 0.0 0.016 14.8 0.0 2.9 1 1 1 3 3 3 1 PQQ-like domain APAF1_C PF17908.1 RUS77360.1 - 0.0014 18.7 0.4 0.0046 17.0 0.1 2.1 2 0 0 2 2 1 1 APAF-1 helical domain AAA_22 PF13401.6 RUS77360.1 - 0.006 16.8 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RUS77360.1 - 0.083 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RUS77360.1 - 0.093 13.1 0.1 0.36 11.2 0.1 2.1 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 RUS77360.1 - 0.15 12.2 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 RUS77360.1 - 0.2 12.1 1.6 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 RUS77360.1 - 0.42 10.6 1.6 0.63 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 RUS77360.1 - 1.3 9.5 0.0 1.3 9.5 0.0 4.0 3 1 0 3 3 2 0 AAA domain SET PF00856.28 RUS77361.1 - 2.3e-10 41.1 1.7 3.3e-09 37.4 0.1 3.2 2 1 0 2 2 2 1 SET domain Dpy-30 PF05186.13 RUS77362.1 - 8.4e-05 22.2 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif Dpy-30 PF05186.13 RUS77363.1 - 0.01 15.5 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Dpy-30 motif EF-hand_7 PF13499.6 RUS77364.1 - 2.8e-11 43.7 2.3 9.4e-10 38.8 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS77364.1 - 3.3e-09 35.7 2.7 0.0011 18.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RUS77364.1 - 3.6e-09 35.8 2.9 0.016 15.1 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RUS77364.1 - 0.0054 16.5 0.2 0.0054 16.5 0.2 2.6 2 1 0 2 2 2 1 EF-hand domain pair DUF494 PF04361.13 RUS77364.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF494) EF-hand_5 PF13202.6 RUS77364.1 - 0.023 14.2 6.2 0.054 13.0 0.1 3.1 3 0 0 3 3 3 0 EF hand Sugar_tr PF00083.24 RUS77365.1 - 9.8e-46 156.5 19.7 1.4e-45 156.0 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS77365.1 - 4.5e-25 88.3 46.1 1.6e-15 56.9 22.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MADF_DNA_bdg PF10545.9 RUS77366.1 - 5.6e-17 61.8 3.0 1.6e-16 60.4 3.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS77366.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_6 PF13921.6 RUS77366.1 - 0.0022 18.2 0.2 0.0059 16.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RUS77366.1 - 0.012 16.0 1.1 0.028 14.8 1.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 RUS77366.1 - 0.027 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4672 PF15716.5 RUS77366.1 - 0.3 10.7 3.0 0.37 10.4 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4672) DNA_pol_phi PF04931.13 RUS77366.1 - 3.1 5.8 8.0 4.4 5.3 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS77366.1 - 5.4 5.2 10.1 1 7.6 6.4 1.6 2 0 0 2 2 2 0 CDC45-like protein CENP-F_leu_zip PF10473.9 RUS77367.1 - 0.0065 16.5 23.3 0.0065 16.5 23.3 9.7 6 2 4 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4041 PF13250.6 RUS77367.1 - 4 7.4 12.5 0.91 9.4 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) zf-C2H2_4 PF13894.6 RUS77369.1 - 4.5e-07 30.2 21.4 0.04 14.8 0.6 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 RUS77369.1 - 7.1e-07 29.4 13.5 0.0055 17.1 0.7 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RUS77369.1 - 1.2e-06 28.6 22.8 0.099 13.1 0.5 5.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2HE PF16278.5 RUS77369.1 - 0.25 11.8 5.6 33 5.0 0.0 4.5 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 RUS77369.1 - 0.4 11.0 19.5 1.5 9.2 0.2 4.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS77369.1 - 0.56 10.7 11.9 3.2 8.3 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger double domain Peptidase_S49_N PF08496.10 RUS77369.1 - 1.6 8.8 10.9 5.5 7.0 10.9 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S15 PF02129.18 RUS77369.1 - 2.1 7.9 8.6 4.7 6.7 8.6 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UL42 PF17638.2 RUS77370.1 - 0.67 9.9 4.7 4.9 7.2 0.3 2.4 2 0 0 2 2 2 0 HCMV UL42 ArfGap PF01412.18 RUS77371.1 - 5e-34 116.9 1.7 1e-33 115.9 0.0 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RUS77371.1 - 2.3e-26 93.0 14.8 5.7e-26 91.7 14.8 1.6 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 RUS77371.1 - 1e-17 64.5 3.4 1.7e-09 38.1 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 RUS77371.1 - 3.5e-12 46.8 1.3 8.6e-12 45.5 0.5 2.1 2 0 0 2 2 2 1 PH domain Ank PF00023.30 RUS77371.1 - 2.2e-07 31.0 0.3 0.0071 16.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS77371.1 - 3.9e-07 30.5 0.2 0.00043 20.8 0.1 3.0 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS77371.1 - 1.7e-06 28.2 0.1 0.0002 21.6 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS77371.1 - 3.7e-06 26.9 0.3 0.36 11.5 0.0 3.6 4 0 0 4 4 3 2 Ankyrin repeat PH_9 PF15410.6 RUS77371.1 - 9.6e-05 22.7 1.4 0.057 13.8 0.1 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain IMD PF08397.11 RUS77371.1 - 0.0015 18.0 2.4 0.0015 18.0 2.4 2.5 1 1 0 2 2 2 1 IRSp53/MIM homology domain Peptidase_C48 PF02902.19 RUS77371.1 - 0.017 15.0 2.0 0.029 14.2 0.2 2.3 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain EF-hand_7 PF13499.6 RUS77372.1 - 1.1e-17 64.2 0.1 4.5e-09 36.6 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS77372.1 - 8.6e-13 47.1 0.1 0.00014 21.5 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RUS77372.1 - 1.9e-10 39.5 0.0 0.00066 19.0 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 RUS77372.1 - 1.9e-08 34.5 0.0 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS77372.1 - 8.9e-08 31.9 0.0 4.7e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair CCD48 PF15799.5 RUS77372.1 - 0.0032 15.9 0.1 1.2 7.3 0.0 2.1 1 1 0 2 2 2 2 Coiled-coil domain-containing protein 48 GPHH PF16905.5 RUS77372.1 - 0.0073 16.0 0.0 15 5.5 0.0 3.8 3 1 1 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated EFhand_Ca_insen PF08726.10 RUS77372.1 - 0.08 13.0 0.5 1.9 8.6 0.1 3.0 3 1 1 4 4 4 0 Ca2+ insensitive EF hand GAGA_bind PF06217.12 RUS77373.1 - 0.085 13.1 22.3 0.11 12.7 22.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3527 PF12043.8 RUS77373.1 - 0.47 10.0 19.3 0.65 9.5 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF4776 PF16003.5 RUS77373.1 - 2.8 6.8 30.7 5 6.0 30.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) MIP PF00230.20 RUS77374.1 - 9.2e-71 238.2 13.6 1.1e-70 237.9 13.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Zip PF02535.22 RUS77375.1 - 0.055 12.7 3.0 0.083 12.1 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 RUS77375.1 - 0.11 13.0 12.3 0.15 12.5 12.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 RUS77375.1 - 0.21 11.0 20.5 0.41 10.1 20.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Eapp_C PF10238.9 RUS77375.1 - 0.45 10.6 12.8 0.94 9.5 12.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein DDHD PF02862.17 RUS77375.1 - 0.85 9.7 7.6 1.2 9.3 7.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.7 RUS77375.1 - 8.7 6.6 26.4 11 6.3 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3821 PF12863.7 RUS77376.1 - 0.95 9.3 6.2 49 3.7 6.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3821) zf_C2H2_10 PF18414.1 RUS77376.1 - 2.2 7.9 3.9 51 3.5 0.1 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger MBOAT PF03062.19 RUS77377.1 - 1.7e-13 50.7 4.7 1.7e-13 50.7 4.7 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family YrzO PF14142.6 RUS77381.1 - 1.6e-07 31.1 7.3 49 3.9 0.0 8.3 9 0 0 9 9 9 0 YrzO-like protein DUF5334 PF17268.2 RUS77381.1 - 0.33 11.3 11.4 15 6.0 0.1 5.0 2 2 5 7 7 7 0 Family of unknown function (DUF5334) DUF745 PF05335.13 RUS77381.1 - 0.45 10.2 1.5 1.5 8.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1601 PF07671.11 RUS77381.1 - 0.77 9.7 16.9 1.6e+02 2.3 0.1 7.6 9 0 0 9 9 9 0 Protein of unknown function (DUF1601) DUF1328 PF07043.13 RUS77382.1 - 0.65 10.3 3.9 1.6e+02 2.6 0.1 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1328) SAM_2 PF07647.17 RUS77383.1 - 2.7e-09 37.0 0.0 8.5e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS77383.1 - 1.7e-08 34.7 0.0 3.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Androgen_recep PF02166.16 RUS77383.1 - 0.038 12.8 6.1 0.064 12.1 6.1 1.3 1 0 0 1 1 1 0 Androgen receptor PI3K_P85_iSH2 PF16454.5 RUS77383.1 - 0.26 10.9 4.8 0.67 9.5 4.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Occludin_ELL PF07303.13 RUS77383.1 - 0.35 11.6 0.1 0.35 11.6 0.1 2.5 3 0 0 3 3 3 0 Occludin homology domain SelP_N PF04592.14 RUS77383.1 - 2.6 7.4 11.6 5.9 6.2 11.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RVT_1 PF00078.27 RUS77385.1 - 3.1e-20 72.7 0.0 4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 RUS77386.1 - 1.4e-75 253.9 0.0 2e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS77386.1 - 5.7e-30 104.6 0.0 8.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MAM PF00629.23 RUS77386.1 - 0.0018 18.2 0.0 0.012 15.6 0.0 2.2 3 0 0 3 3 3 1 MAM domain, meprin/A5/mu Gly_rich PF12810.7 RUS77386.1 - 0.0033 17.4 6.2 0.011 15.7 6.2 1.7 1 1 0 1 1 1 1 Glycine rich protein Pkinase_fungal PF17667.1 RUS77386.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RUS77386.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like OPA3 PF07047.12 RUS77389.1 - 1.2e-39 135.0 0.0 1.6e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Cnn_1N PF07989.11 RUS77389.1 - 0.1 12.8 2.2 0.3 11.3 2.2 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 S_4TM PF18159.1 RUS77389.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain TMPIT PF07851.13 RUS77389.1 - 0.19 11.0 2.9 0.26 10.5 2.4 1.5 1 1 1 2 2 2 0 TMPIT-like protein DHHC PF01529.20 RUS77391.1 - 1.7e-23 83.2 7.9 1.7e-23 83.2 7.9 1.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase Lectin_C_term PF18022.1 RUS77391.1 - 0.071 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain Tetradecapep PF08187.11 RUS77391.1 - 0.085 12.9 0.9 0.24 11.5 0.9 1.8 1 1 0 1 1 1 0 Myoactive tetradecapeptides family DHHC PF01529.20 RUS77392.1 - 2e-29 102.4 11.4 2e-29 102.4 11.4 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase UBX PF00789.20 RUS77393.1 - 2.7e-22 78.7 0.1 7.5e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 RUS77393.1 - 1.2e-07 31.4 0.1 3.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain APG6_N PF17675.1 RUS77393.1 - 0.43 11.1 28.7 1.1 9.8 28.7 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5401 PF17380.2 RUS77393.1 - 2 6.4 27.8 2.5 6.0 27.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA_11 PF13086.6 RUS77393.1 - 5 6.8 16.2 30 4.3 17.0 1.8 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.26 RUS77394.1 - 6.1e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dynamin_M PF01031.20 RUS77394.1 - 0.066 12.4 2.0 2.3 7.3 0.1 2.9 2 1 1 3 3 3 0 Dynamin central region S1 PF00575.23 RUS77395.1 - 0.0043 17.4 0.2 0.0066 16.8 0.2 1.2 1 0 0 1 1 1 1 S1 RNA binding domain Fibrinogen_C PF00147.18 RUS77396.1 - 4.3e-32 111.7 0.0 4.8e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EF-hand_7 PF13499.6 RUS77397.1 - 1.1e-19 70.6 16.0 3.6e-10 40.1 0.4 3.4 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS77397.1 - 2.8e-19 67.3 6.0 6.2e-06 25.7 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 RUS77397.1 - 3.4e-17 60.6 10.7 7e-08 31.5 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 RUS77397.1 - 3.4e-16 58.8 8.2 3.7e-12 45.9 1.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS77397.1 - 1.9e-15 55.6 3.9 4.4e-07 29.1 0.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 RUS77397.1 - 0.039 14.3 0.1 8.3 6.8 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain EF-hand_14 PF17959.1 RUS77397.1 - 0.15 12.4 0.0 19 5.7 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain TPR_14 PF13428.6 RUS77399.1 - 0.0017 19.0 0.1 0.0064 17.2 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS77399.1 - 0.0029 18.1 0.1 0.0066 16.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77399.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS77399.1 - 0.07 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS77399.1 - 0.091 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Cadherin-like PF12733.7 RUS77400.1 - 7.2e-27 93.7 0.1 6.9e-14 52.1 0.8 2.8 3 0 0 3 3 3 2 Cadherin-like beta sandwich domain TPR_19 PF14559.6 RUS77400.1 - 0.00022 21.7 0.4 0.11 13.0 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77400.1 - 0.00045 19.8 0.2 1.4 8.6 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 RUS77400.1 - 0.0011 19.2 0.7 5.6 7.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS77400.1 - 0.0031 18.1 4.2 0.017 15.7 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77400.1 - 0.0071 16.4 0.3 5.2 7.4 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat XRN_M PF17846.1 RUS77401.1 - 1.5e-168 561.4 0.0 2e-168 560.9 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 RUS77401.1 - 1.1e-100 336.1 0.0 2e-100 335.2 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF4689 PF15755.5 RUS77402.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Homeodomain PF00046.29 RUS77403.1 - 5.6e-20 70.9 2.7 8.8e-20 70.3 2.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS77403.1 - 0.053 13.4 0.5 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Homeobox KN domain Macoilin PF09726.9 RUS77403.1 - 9.7 4.6 9.7 14 4.0 9.7 1.3 1 0 0 1 1 1 0 Macoilin family IFRD PF05004.13 RUS77404.1 - 0.00042 19.5 1.0 0.0063 15.7 0.1 2.1 1 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 RUS77404.1 - 0.0032 17.6 0.5 0.021 15.0 0.0 2.4 3 0 0 3 3 3 1 HEAT repeat M11L PF11099.8 RUS77404.1 - 0.095 13.0 0.2 7.8 6.7 0.3 2.1 2 0 0 2 2 2 0 Apoptosis regulator M11L like Pkinase PF00069.25 RUS77405.1 - 1.9e-66 224.1 0.0 2.6e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77405.1 - 9e-41 139.9 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 RUS77405.1 - 7.5e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Haspin_kinase PF12330.8 RUS77405.1 - 0.0018 17.3 0.7 0.24 10.3 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS77405.1 - 0.0042 15.9 0.0 0.0096 14.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS77405.1 - 0.0045 16.4 0.1 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS77405.1 - 0.049 13.2 0.4 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family ETC_C1_NDUFA4 PF04800.12 RUS77406.1 - 4.6e-39 132.6 1.3 6e-39 132.2 1.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region RVT_1 PF00078.27 RUS77407.1 - 9.8e-07 28.5 0.1 1.4e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pribosyltran PF00156.27 RUS77408.1 - 6.1e-24 84.3 0.0 9.1e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RUS77408.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Kelch_1 PF01344.25 RUS77410.1 - 4.5e-73 240.6 15.1 1.2e-15 56.9 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS77410.1 - 1.6e-47 158.3 6.8 5.4e-09 36.0 0.1 6.5 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RUS77410.1 - 6.8e-27 92.4 8.3 2.5e-06 27.3 0.1 6.6 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 RUS77410.1 - 5.3e-25 87.8 0.1 1.1e-12 48.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Kelch_4 PF13418.6 RUS77410.1 - 8.4e-24 83.3 3.6 0.0017 18.3 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 RUS77410.1 - 1.9e-22 79.3 2.1 3.9e-22 78.3 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RUS77410.1 - 6e-22 77.4 9.6 2.4e-06 27.7 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS77410.1 - 2e-12 46.8 10.0 0.00073 19.5 0.3 6.1 6 0 0 6 6 6 4 Kelch motif zf-RING_2 PF13639.6 RUS77411.1 - 8e-13 48.5 21.7 1.8e-09 37.8 6.8 3.8 4 0 0 4 4 2 2 Ring finger domain zf-RING_11 PF17123.5 RUS77411.1 - 1.4e-08 34.3 3.0 1.4e-08 34.3 3.0 2.9 2 0 0 2 2 2 1 RING-like zinc finger SWIM PF04434.17 RUS77411.1 - 2.4e-07 30.3 3.6 2.5e-07 30.2 1.2 2.3 2 0 0 2 2 2 1 SWIM zinc finger ZZ PF00569.17 RUS77411.1 - 3.4e-07 30.0 9.1 1.4e-06 28.0 9.1 2.1 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 RUS77411.1 - 6.3e-05 22.7 6.7 6.3e-05 22.7 6.7 3.9 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS77411.1 - 7.4e-05 22.5 4.5 7.4e-05 22.5 4.5 4.1 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS77411.1 - 0.001 19.3 6.3 0.001 19.3 6.3 3.7 3 0 0 3 3 2 2 RING-H2 zinc finger domain FANCL_C PF11793.8 RUS77411.1 - 0.061 13.5 18.8 0.022 14.9 4.5 3.2 3 0 0 3 3 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 RUS77411.1 - 0.11 12.3 2.0 4.2 7.3 0.2 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 RUS77411.1 - 0.18 11.8 1.4 6.8 6.7 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_UBOX PF13445.6 RUS77411.1 - 0.87 9.7 26.6 0.38 10.8 4.0 3.5 3 1 0 3 3 3 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 RUS77411.1 - 1.5 8.9 24.2 0.049 13.7 4.0 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 RUS77411.1 - 2.4 8.4 20.4 3.5 7.8 6.8 2.9 2 0 0 2 2 2 0 RING-variant domain DAN PF03045.15 RUS77412.1 - 1e-05 25.5 11.4 1.2e-05 25.2 7.7 2.0 1 1 0 2 2 2 1 DAN domain DAN PF03045.15 RUS77413.1 - 1.1e-05 25.4 6.0 1.7e-05 24.8 6.0 1.3 1 0 0 1 1 1 1 DAN domain C2 PF00168.30 RUS77413.1 - 0.023 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain MFS_1 PF07690.16 RUS77414.1 - 2.7e-16 59.4 24.8 2.7e-16 59.4 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 RUS77414.1 - 2e-06 26.7 17.4 2e-06 26.7 17.4 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 RUS77414.1 - 2.7e-06 26.7 17.1 5.2e-06 25.7 17.1 1.5 1 1 0 1 1 1 1 PUCC protein MFS_1_like PF12832.7 RUS77414.1 - 2.8e-05 23.1 11.9 0.0027 16.6 1.1 2.9 1 1 1 3 3 3 2 MFS_1 like family DUF3377 PF11857.8 RUS77414.1 - 0.012 15.5 0.2 0.039 13.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3487 PF11990.8 RUS77414.1 - 0.039 13.8 0.5 0.039 13.8 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3487) RRM_4 PF10598.9 RUS77414.1 - 0.77 10.1 4.2 4.8 7.6 0.2 2.5 2 1 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 Alk_phosphatase PF00245.20 RUS77415.1 - 9.5e-33 113.7 0.1 1.1e-32 113.6 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase EMC1_C PF07774.13 RUS77416.1 - 2.5e-47 161.3 0.5 7.3e-47 159.8 0.0 2.1 3 0 0 3 3 3 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 RUS77416.1 - 1.2e-13 51.2 0.8 6.9e-09 35.6 0.6 3.8 4 1 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 RUS77416.1 - 0.18 11.8 0.0 26 5.0 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Cut8 PF08559.10 RUS77417.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 Cut8, nuclear proteasome tether protein Mucin PF01456.17 RUS77417.1 - 0.017 15.2 0.3 0.022 14.8 0.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1403 PF07183.11 RUS77418.1 - 0.00066 19.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1403) Exo_endo_phos_2 PF14529.6 RUS77418.1 - 0.0026 17.6 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS77418.1 - 0.051 13.1 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family THAP PF05485.12 RUS77419.1 - 0.013 16.4 0.2 0.018 15.9 0.2 1.2 1 0 0 1 1 1 0 THAP domain Tubulin PF00091.25 RUS77420.1 - 7.6e-67 225.3 0.0 1.2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS77420.1 - 7.3e-42 142.5 0.0 1.1e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS77420.1 - 0.0001 22.6 0.0 0.0003 21.1 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS77420.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain PHF5 PF03660.14 RUS77421.1 - 2e-50 169.3 13.0 2.3e-50 169.2 13.0 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 RUS77421.1 - 0.35 8.7 9.1 0.35 8.7 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 BAH PF01426.18 RUS77422.1 - 3.3e-13 49.6 0.0 6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 BAH domain Tudor_3 PF18115.1 RUS77422.1 - 7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 RUS77422.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 RUS77422.1 - 0.00027 20.6 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 SO_alpha_A3 PF17806.1 RUS77423.1 - 0.053 13.9 0.3 19 5.6 0.0 2.8 3 0 0 3 3 3 0 Sarcosine oxidase A3 domain Lactamase_B_2 PF12706.7 RUS77424.1 - 4.6e-17 62.2 0.4 7.3e-15 55.0 3.8 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 RUS77424.1 - 1.6e-10 40.5 0.1 2.6e-09 36.6 0.0 2.8 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 RUS77424.1 - 4.9e-07 30.0 0.0 0.00013 22.0 0.1 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PCI PF01399.27 RUS77425.1 - 5.2e-10 39.8 0.1 1.5e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_1 PF00515.28 RUS77425.1 - 0.2 11.5 2.5 0.42 10.5 1.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77425.1 - 0.68 10.2 3.0 0.66 10.2 1.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ric8 PF10165.9 RUS77426.1 - 4.5e-65 220.5 0.0 5.1e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn LRRC37AB_C PF14914.6 RUS77426.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain cNMP_binding PF00027.29 RUS77429.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cpta_toxin PF07254.12 RUS77430.1 - 0.93 9.5 4.5 5.2 7.1 0.5 2.3 1 1 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system CBM_20 PF00686.19 RUS77431.1 - 2e-19 69.3 1.0 1.8e-09 37.4 0.2 2.4 2 0 0 2 2 2 2 Starch binding domain Synuclein PF01387.17 RUS77432.1 - 0.12 12.5 1.8 2.6 8.3 0.2 3.0 2 1 0 2 2 2 0 Synuclein ADH_zinc_N PF00107.26 RUS77433.1 - 4.5e-24 84.9 0.0 9.5e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS77433.1 - 8.2e-13 49.6 0.0 1.9e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS77433.1 - 2.7e-07 30.4 0.0 3.6e-06 26.8 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS77433.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase PGM_PMM_II PF02879.16 RUS77433.1 - 0.15 12.7 0.1 0.92 10.2 0.0 2.3 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II COesterase PF00135.28 RUS77434.1 - 4.6e-26 91.8 0.2 5.6e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Tetraspanin PF00335.20 RUS77435.1 - 0.00016 21.5 1.2 0.0002 21.2 1.2 1.1 1 0 0 1 1 1 1 Tetraspanin family PH_BEACH PF14844.6 RUS77435.1 - 0.073 13.2 0.1 0.092 12.9 0.1 1.2 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Tetraspanin PF00335.20 RUS77436.1 - 1.4e-10 41.3 15.8 1.6e-10 41.1 15.8 1.0 1 0 0 1 1 1 1 Tetraspanin family IPTL-CTERM PF18203.1 RUS77436.1 - 1.1 9.2 0.1 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 IPTL-CTERM motif Phage_holin_2_4 PF16082.5 RUS77436.1 - 8.3 6.2 8.1 1.4 8.7 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Hum_adeno_E3A PF05393.11 RUS77438.1 - 0.0011 18.9 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein EF-hand_8 PF13833.6 RUS77439.1 - 5.5e-11 42.1 5.3 5.1e-05 23.0 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RUS77439.1 - 2.1e-10 39.4 10.6 0.00015 21.1 0.0 4.1 2 2 2 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS77439.1 - 5.2e-10 39.6 10.2 2.2e-06 28.0 4.0 3.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS77439.1 - 3.5e-08 32.7 11.7 0.00071 19.3 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS77439.1 - 7.7e-08 31.5 1.5 0.0033 16.8 0.0 3.4 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 RUS77439.1 - 0.0039 17.5 2.0 1.5 9.1 0.1 3.3 1 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 RUS77439.1 - 0.012 15.6 1.0 0.05 13.5 0.0 2.0 1 1 0 2 2 2 0 Caleosin related protein Dockerin_1 PF00404.18 RUS77439.1 - 1.6 9.0 0.1 1.6 9.0 0.1 3.3 2 2 2 4 4 4 0 Dockerin type I domain DUF5342 PF17277.2 RUS77440.1 - 0.15 12.5 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5342) RGS PF00615.19 RUS77443.1 - 2.4e-34 118.1 2.4 3.7e-34 117.5 2.4 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3507 PF12015.8 RUS77443.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3507) DNA_gyraseB_C PF00986.21 RUS77443.1 - 0.085 13.1 0.3 20 5.4 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Synapsin_N PF10581.9 RUS77443.1 - 0.13 12.2 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Synapsin N-terminal RhoGEF PF00621.20 RUS77444.1 - 4.2e-39 134.7 4.0 9.4e-39 133.5 4.0 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 RUS77444.1 - 1.4e-19 69.4 0.4 3.1e-13 49.1 0.0 2.8 2 0 0 2 2 2 2 SH3 domain CH PF00307.31 RUS77444.1 - 2.1e-19 69.7 0.1 5.2e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS77444.1 - 7.7e-17 60.9 0.1 1.7e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain SH2 PF00017.24 RUS77444.1 - 1.4e-16 60.3 0.0 3.6e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 RUS77444.1 - 5.1e-14 51.9 0.2 6.2e-08 32.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 RUS77444.1 - 7.1e-14 51.2 0.1 1.8e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.29 RUS77444.1 - 4.2e-08 33.6 1.1 7.7e-08 32.8 0.2 2.0 2 0 0 2 2 2 1 PH domain CDC24 PF06395.11 RUS77444.1 - 8.8e-07 29.1 0.2 2.7e-06 27.5 0.2 1.9 1 0 0 1 1 1 1 CDC24 Calponin C1_1 PF00130.22 RUS77444.1 - 1.2e-06 28.3 0.4 2.9e-06 27.1 0.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_10 PF15411.6 RUS77444.1 - 6.3e-05 23.2 3.8 0.00022 21.4 0.2 2.9 2 1 1 3 3 3 1 Pleckstrin homology domain PH_5 PF15405.6 RUS77444.1 - 0.0019 18.3 0.4 1.4 9.0 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain zf-RING-like PF08746.11 RUS77444.1 - 0.017 15.4 2.0 0.045 14.1 0.3 2.4 2 0 0 2 2 2 0 RING-like domain C1_2 PF03107.16 RUS77444.1 - 0.082 13.2 1.1 0.23 11.8 1.1 1.8 1 0 0 1 1 1 0 C1 domain Neprosin PF03080.15 RUS77444.1 - 0.11 11.9 0.3 2.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Neprosin Peptidase_S9 PF00326.21 RUS77445.1 - 0.0033 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 RUS77445.1 - 0.0071 16.2 0.0 0.0093 15.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Flavodoxin_1 PF00258.25 RUS77445.1 - 0.17 12.1 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin Ribosom_S30AE_C PF16321.5 RUS77446.1 - 0.0012 18.4 6.8 4.1 7.2 0.1 4.6 1 1 4 5 5 5 3 Sigma 54 modulation/S30EA ribosomal protein C terminus ANAPC9 PF12856.7 RUS77446.1 - 0.22 11.7 12.1 33 4.7 0.5 6.1 1 1 6 7 7 7 0 Anaphase-promoting complex subunit 9 Coronavirus_5 PF05528.11 RUS77446.1 - 1.8 8.6 19.6 41 4.2 1.6 6.4 1 1 6 7 7 7 0 Coronavirus gene 5 protein HIF-1a_CTAD PF08778.10 RUS77446.1 - 7.7 6.2 21.5 1.3e+02 2.3 0.1 7.5 8 0 0 8 8 8 0 HIF-1 alpha C terminal transactivation domain DUF872 PF05915.12 RUS77447.1 - 0.00088 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF4245 PF14030.6 RUS77447.1 - 0.0046 17.0 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) DUF4307 PF14155.6 RUS77447.1 - 0.0068 16.2 0.2 0.034 14.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4307) Amastin PF07344.11 RUS77447.1 - 0.027 14.3 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF5527 PF17665.1 RUS77447.1 - 0.13 11.8 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Synaptobrevin PF00957.21 RUS77447.1 - 2.6 7.9 4.4 4.1 7.3 4.4 1.2 1 0 0 1 1 1 0 Synaptobrevin SNARE PF05739.19 RUS77447.1 - 4.2 7.4 9.4 18 5.4 7.0 2.6 2 2 0 2 2 2 0 SNARE domain ADIP PF11559.8 RUS77448.1 - 0.001 19.1 9.4 0.093 12.8 3.5 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DUF4988 PF16378.5 RUS77448.1 - 0.0021 17.8 15.3 0.38 10.4 1.7 3.2 1 1 2 3 3 3 3 Domain of unknown function LPP PF04728.13 RUS77448.1 - 0.0077 16.6 3.3 3.3 8.2 0.1 4.0 1 1 3 4 4 4 1 Lipoprotein leucine-zipper MscS_porin PF12795.7 RUS77448.1 - 0.01 15.4 0.1 0.67 9.5 0.1 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4686 PF15742.5 RUS77448.1 - 0.013 14.7 6.5 0.17 11.0 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) TSC22 PF01166.18 RUS77448.1 - 0.018 15.3 10.8 1.8 8.9 1.6 3.8 1 1 3 4 4 4 0 TSC-22/dip/bun family bZIP_1 PF00170.21 RUS77448.1 - 0.025 14.7 7.5 0.58 10.3 0.4 2.9 1 1 3 4 4 4 0 bZIP transcription factor PEARLI-4 PF05278.12 RUS77448.1 - 0.031 13.9 12.5 0.62 9.6 4.1 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) CLZ PF16526.5 RUS77448.1 - 0.043 14.2 12.3 5 7.5 1.8 3.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspA_IM30 PF04012.12 RUS77448.1 - 0.044 13.4 14.9 0.67 9.5 1.8 2.6 1 1 1 2 2 2 0 PspA/IM30 family NPV_P10 PF05531.12 RUS77448.1 - 0.044 14.2 23.8 0.72 10.4 6.4 3.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HCMV_UL139 PF12507.8 RUS77448.1 - 0.1 13.0 7.2 4.9 7.6 1.5 3.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein HipN PF18253.1 RUS77448.1 - 0.16 11.7 7.2 28 4.5 0.0 4.1 2 2 2 4 4 4 0 Hsp70-interacting protein N N-terminal domain Nup54 PF13874.6 RUS77448.1 - 0.17 12.0 4.5 0.25 11.5 4.5 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SlyX PF04102.12 RUS77448.1 - 0.17 12.5 3.4 7.2 7.3 0.5 2.6 1 1 3 4 4 4 0 SlyX ZapB PF06005.12 RUS77448.1 - 0.19 12.2 6.4 1 9.8 1.1 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 RUS77448.1 - 0.26 10.3 8.4 1.6 7.8 7.9 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GOLGA2L5 PF15070.6 RUS77448.1 - 0.41 9.2 4.7 2 7.0 0.5 2.0 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF16 PF01519.16 RUS77448.1 - 0.96 10.0 15.1 2.2e+03 -0.8 15.1 2.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 CtIP_N PF10482.9 RUS77448.1 - 1.5 8.9 6.5 7 6.7 2.6 2.5 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 RUS77448.1 - 1.9 8.5 15.8 8.7 6.4 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 RUS77448.1 - 1.9 8.7 4.5 7.5 6.7 4.4 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 RUS77448.1 - 2.4 8.5 13.7 16 5.9 0.7 3.4 1 1 3 4 4 4 0 Csm1 N-terminal domain USP8_interact PF08941.10 RUS77448.1 - 3.2 7.5 8.7 15 5.3 3.0 2.3 1 1 1 2 2 2 0 USP8 interacting NBP1 PF08537.10 RUS77448.1 - 7.6 5.8 12.4 1.3e+03 -1.5 12.4 2.5 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 DPPIV_N PF00930.21 RUS77449.1 - 1e-80 271.2 0.3 1.3e-80 270.8 0.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 RUS77449.1 - 1.5e-56 191.2 3.2 2.4e-56 190.6 3.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 RUS77449.1 - 0.00016 21.3 0.1 0.00047 19.8 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 RUS77449.1 - 0.00084 18.7 0.9 0.16 11.2 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RUS77449.1 - 0.00093 18.9 0.6 0.023 14.3 0.1 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 RUS77449.1 - 0.003 18.2 0.0 0.021 15.4 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RUS77449.1 - 0.02 14.7 0.3 1 9.1 0.2 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 RUS77449.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 RUS77449.1 - 0.049 12.3 0.0 0.33 9.6 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Vfa1 PF08432.10 RUS77449.1 - 0.05 13.9 2.5 0.083 13.2 2.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1682 PF07946.14 RUS77449.1 - 3.2 6.9 11.2 5.1 6.2 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Trypan_PARP PF05887.11 RUS77449.1 - 6.9 6.7 5.6 13 5.8 5.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neur_chan_memb PF02932.16 RUS77450.1 - 3.7e-14 53.4 6.9 9.8e-10 38.9 6.3 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS77450.1 - 3.9e-13 49.4 0.1 6.1e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 RUS77450.1 - 1.3 8.4 7.8 3.7 6.9 7.8 2.0 1 1 0 1 1 1 0 Region of unknown function (DUF2417) PHTB1_C PF14728.6 RUS77451.1 - 5.3e-137 456.9 0.0 9.4e-137 456.1 0.0 1.4 2 0 0 2 2 2 1 PTHB1 C-terminus PHTB1_N PF14727.6 RUS77451.1 - 3.4e-136 454.9 0.0 5.5e-103 345.5 0.0 2.1 1 1 1 2 2 2 2 PTHB1 N-terminus Sec23_BS PF08033.12 RUS77451.1 - 0.15 12.8 0.2 0.6 10.9 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain Alanine_zipper PF11839.8 RUS77454.1 - 8 6.9 10.0 74 3.8 10.0 2.3 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF2115 PF09888.9 RUS77455.1 - 0.015 15.9 6.7 0.44 11.0 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2115) PDEase_I_N PF08499.12 RUS77455.1 - 0.057 13.3 7.2 27 4.7 0.7 5.2 5 0 0 5 5 5 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Cu_amine_oxid PF01179.20 RUS77456.1 - 3.2e-94 316.2 7.4 3.4e-53 181.1 0.1 3.1 1 1 1 3 3 3 3 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 RUS77456.1 - 1.6e-09 37.9 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ras PF00071.22 RUS77457.1 - 3.6e-32 111.2 0.1 5e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS77457.1 - 2.2e-09 37.5 0.0 4.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS77457.1 - 0.0075 16.2 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 RUS77457.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Pro_isomerase PF00160.21 RUS77458.1 - 6.5e-19 68.7 0.1 8.2e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 RUS77459.1 - 6.6e-34 117.5 0.0 8.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP_assoc PF03828.19 RUS77459.1 - 0.042 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Cid1 family poly A polymerase DUF3769 PF12600.8 RUS77461.1 - 0.19 10.5 1.1 0.27 10.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) Y_phosphatase PF00102.27 RUS77463.1 - 4.9e-44 150.7 0.2 5.5e-44 150.5 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS77463.1 - 0.0019 18.2 0.0 0.012 15.6 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 RUS77463.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2683 PF10884.8 RUS77463.1 - 0.056 13.7 0.1 5.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Bcl-2 PF00452.19 RUS77464.1 - 8.8e-22 77.7 0.7 1.4e-21 77.1 0.7 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CZB PF13682.6 RUS77464.1 - 0.024 15.1 0.6 0.045 14.2 0.6 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain BILBO1_N PF18281.1 RUS77464.1 - 0.096 13.1 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 BILBO1 N-terminal domain DUF4219 PF13961.6 RUS77465.1 - 6.6e-06 25.7 4.9 23 4.8 0.0 7.8 11 0 0 11 11 11 4 Domain of unknown function (DUF4219) Viral_Rep PF02407.16 RUS77465.1 - 6.6 7.1 23.0 17 5.8 0.1 6.6 4 2 3 7 7 7 0 Putative viral replication protein KH_5 PF13184.6 RUS77466.1 - 0.0033 17.5 1.5 19 5.4 0.6 4.7 2 1 0 2 2 2 1 NusA-like KH domain CheD PF03975.13 RUS77466.1 - 0.0073 16.4 6.6 0.58 10.3 0.3 3.8 1 1 3 4 4 4 2 CheD chemotactic sensory transduction Epsilon_antitox PF08998.11 RUS77466.1 - 0.094 13.0 1.2 17 5.8 0.0 3.0 2 1 2 4 4 4 0 Bacterial epsilon antitoxin Ribosomal_S8e PF01201.22 RUS77466.1 - 0.3 11.3 9.8 5.9e+02 0.6 9.8 3.7 1 1 0 1 1 1 0 Ribosomal protein S8e Pyocin_S PF06958.12 RUS77466.1 - 1.3 9.6 5.7 14 6.2 0.7 3.0 1 1 2 3 3 3 0 S-type Pyocin Trehalase_Ca-bi PF07492.11 RUS77467.1 - 2.5e-07 30.3 25.2 32 4.3 0.2 10.1 10 0 0 10 10 10 0 Neutral trehalase Ca2+ binding domain DUF4649 PF15507.6 RUS77467.1 - 0.00012 22.0 0.0 9.7 6.2 0.0 3.9 1 1 3 4 4 4 1 Domain of unknown function (DUF4649) DUF4840 PF16128.5 RUS77467.1 - 0.0018 18.3 1.2 0.12 12.4 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4840) DUF4268 PF14088.6 RUS77467.1 - 0.0055 16.6 5.1 2.5 7.9 0.2 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4268) RMI1_C PF16099.5 RUS77467.1 - 0.011 15.6 9.4 3.8 7.3 0.4 3.5 1 1 2 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Calycin_like PF13944.6 RUS77467.1 - 0.026 14.8 17.7 24 5.2 2.4 4.5 1 1 1 2 2 2 0 Calycin-like beta-barrel domain DUF4773 PF15998.5 RUS77467.1 - 0.12 12.9 7.1 16 6.0 2.7 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4773) MazG PF03819.17 RUS77467.1 - 0.14 12.4 0.0 9.5 6.5 0.0 2.5 2 1 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain DNA_pol3_beta PF00712.19 RUS77467.1 - 0.61 10.2 14.3 1.8 8.7 5.6 2.4 1 1 1 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain SpoVG PF04026.12 RUS77467.1 - 0.62 10.3 12.6 8.2 6.7 2.6 4.3 1 1 2 3 3 3 0 SpoVG DUF3823_C PF18003.1 RUS77467.1 - 0.82 10.4 7.9 1.5e+02 3.2 7.9 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3823_C) ITI_HC_C PF06668.12 RUS77467.1 - 1.4 8.6 8.4 3.6 7.2 2.8 2.1 1 1 0 2 2 2 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF4412 PF14371.6 RUS77467.1 - 4.7 7.0 8.5 5.5 6.7 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4412) AbiGii_2 PF16873.5 RUS77467.1 - 8.8 4.9 30.7 4.3 6.0 7.3 3.2 1 1 2 3 3 3 0 Putative abortive phage resistance protein AbiGii toxin adh_short PF00106.25 RUS77468.1 - 4.6e-21 75.2 0.0 7.3e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS77468.1 - 5e-11 42.6 0.1 5.5e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pentapeptide_3 PF13576.6 RUS77469.1 - 1.5e-12 47.5 0.2 3.5e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 RUS77469.1 - 4.8e-10 38.9 0.0 0.0007 19.2 0.0 2.9 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 RUS77469.1 - 0.0053 16.9 0.0 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Phtf-FEM1B_bdg PF12129.8 RUS77469.1 - 0.61 9.9 4.5 29 4.4 0.2 3.0 1 1 3 4 4 4 0 Male germ-cell putative homeodomain transcription factor FERM_N_2 PF18038.1 RUS77469.1 - 4.4 8.2 8.6 8.9 7.2 0.0 4.3 3 1 2 5 5 5 0 FERM N-terminal domain adh_short PF00106.25 RUS77470.1 - 1.8e-14 53.7 0.0 1e-12 47.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS77470.1 - 7.2e-08 32.3 0.0 4.5e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.25 RUS77471.1 - 5.6e-13 49.1 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS77471.1 - 1.2e-08 34.9 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS77471.1 - 1.6e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS77471.1 - 4.8e-05 23.2 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 RUS77471.1 - 0.0038 17.9 0.0 0.0049 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 RUS77471.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_CG PF14542.6 RUS77471.1 - 0.076 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3668 PF12416.8 RUS77471.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein MFS_1 PF07690.16 RUS77472.1 - 8e-10 38.2 22.8 4.8e-06 25.7 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS77472.1 - 2.4e-07 30.4 10.0 3e-07 30.1 10.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 RUS77472.1 - 0.036 12.4 8.6 0.038 12.3 1.4 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS77473.1 - 0.39 9.6 16.2 0.36 9.7 14.6 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Rieske PF00355.26 RUS77474.1 - 5.9e-15 55.0 0.1 1.3e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 RUS77474.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain WD40 PF00400.32 RUS77475.1 - 1.1e-12 48.2 11.6 0.0012 19.6 0.6 6.0 4 1 0 4 4 4 4 WD domain, G-beta repeat Dicty_REP PF05086.12 RUS77475.1 - 5.7 4.8 8.6 9.1 4.1 8.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_38N PF01074.22 RUS77476.1 - 1.1e-80 271.1 8.8 1.9e-79 267.1 8.8 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS77476.1 - 2.6e-33 115.9 0.0 4.2e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RUS77476.1 - 2e-20 72.7 0.0 4.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 RUS77476.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MgtE_N PF03448.17 RUS77478.1 - 3.6e-10 40.3 34.6 0.0048 17.5 7.5 3.7 1 1 1 2 2 2 1 MgtE intracellular N domain Nse4-Nse3_bdg PF15412.6 RUS77478.1 - 7.3e-05 22.8 25.3 3.6e+02 1.3 6.2 8.9 1 1 1 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Band_7 PF01145.25 RUS77478.1 - 0.001 19.1 0.5 1 9.3 0.5 3.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Minor_tail_Z PF06763.11 RUS77478.1 - 0.0067 16.2 29.9 1.1e+02 2.4 7.7 5.5 1 1 1 2 2 2 0 Prophage minor tail protein Z (GPZ) DUF445 PF04286.12 RUS77478.1 - 0.0091 15.8 20.1 0.021 14.6 20.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF445) GlutR_dimer PF00745.20 RUS77478.1 - 0.071 13.6 26.6 2.3e+02 2.3 11.8 4.8 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain TetR_C_19 PF17924.1 RUS77478.1 - 0.13 12.9 33.0 2.2 8.9 6.6 3.6 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Host_attach PF10116.9 RUS77478.1 - 0.2 12.3 5.8 89 3.7 5.8 4.0 1 1 0 1 1 1 0 Protein required for attachment to host cells MetOD1 PF18546.1 RUS77478.1 - 0.39 10.7 41.2 1e+02 2.8 14.7 4.2 1 1 1 2 2 2 0 Metanogen output domain 1 Tam41_Mmp37 PF09139.11 RUS77478.1 - 1.5 8.2 26.8 1.8e+04 -5.8 26.8 2.7 1 1 0 1 1 0 0 Phosphatidate cytidylyltransferase, mitochondrial MADF_DNA_bdg PF10545.9 RUS77478.1 - 5.2 7.4 8.8 3.6e+03 -1.6 8.8 3.8 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MukF_C PF17193.4 RUS77478.1 - 5.2 7.2 21.2 1.8e+04 -9.4 21.2 3.7 1 1 0 1 1 0 0 MukF C-terminal domain ATP-cone PF03477.16 RUS77478.1 - 6.8 7.3 19.8 1.8e+04 -10.5 19.8 4.9 1 1 0 1 1 0 0 ATP cone domain YpjP PF14005.6 RUS77478.1 - 8.3 6.5 26.1 17 5.4 5.7 3.1 1 1 1 2 2 2 0 YpjP-like protein Neur_chan_LBD PF02931.23 RUS77479.1 - 6.3e-30 104.2 0.8 8.2e-30 103.9 0.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS77479.1 - 8.9e-18 65.2 0.6 1.1e-17 64.9 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2304 PF10066.9 RUS77479.1 - 0.51 10.6 3.6 0.93 9.7 3.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DivIC PF04977.15 RUS77480.1 - 0.074 12.8 1.3 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator SPT2 PF08243.11 RUS77480.1 - 0.34 11.5 12.3 0.64 10.6 12.3 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein Wbp11 PF09429.10 RUS77481.1 - 1.2e-20 73.7 8.1 1.2e-20 73.7 8.1 2.8 3 0 0 3 3 3 1 WW domain binding protein 11 SOAR PF16533.5 RUS77481.1 - 0.029 14.3 0.4 0.029 14.3 0.4 2.1 3 0 0 3 3 3 0 STIM1 Orai1-activating region Forkhead PF00250.18 RUS77483.1 - 1.2e-35 121.6 0.2 1.9e-35 121.0 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain Ribosomal_S5 PF00333.20 RUS77484.1 - 4.1e-31 106.8 0.6 8e-31 105.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RUS77484.1 - 6.1e-25 86.5 0.0 9.7e-25 85.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RUS77484.1 - 1.1 9.8 13.5 3 8.4 13.5 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RT_RNaseH_2 PF17919.1 RUS77485.1 - 2e-32 111.2 0.0 4.1e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS77485.1 - 8.5e-29 99.9 0.0 1.6e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77485.1 - 5.5e-25 88.2 0.0 9.2e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS77485.1 - 6.2e-23 81.2 0.0 1.8e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS77485.1 - 1e-15 57.6 1.1 2.1e-15 56.6 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 RUS77485.1 - 0.002 18.4 0.0 0.0061 16.8 0.0 1.8 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.6 RUS77485.1 - 0.008 15.9 0.1 0.034 13.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain P22_Cro PF14549.6 RUS77485.1 - 0.026 14.4 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro zf-H2C2 PF09337.10 RUS77485.1 - 0.036 14.3 0.1 0.089 13.0 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger ubiquitin PF00240.23 RUS77486.1 - 1.1e-13 50.8 0.7 2.6e-13 49.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 RUS77486.1 - 0.00022 21.0 0.1 0.00039 20.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4366 PF14283.6 RUS77486.1 - 0.18 11.8 3.2 0.25 11.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) INSIG PF07281.12 RUS77487.1 - 8.5e-47 159.5 9.4 7e-46 156.6 9.4 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF202 PF02656.15 RUS77487.1 - 0.47 10.9 7.6 0.37 11.3 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) CPP1-like PF11833.8 RUS77487.1 - 0.66 9.6 3.4 4.5 6.9 0.8 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NDUF_B12 PF08122.12 RUS77487.1 - 1.1 9.4 5.8 6.8 6.8 0.4 3.6 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family KOG2701 PF09762.9 RUS77488.1 - 6.3e-77 257.8 0.0 6.3e-77 257.8 0.0 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein (DUF2037) DUF3736 PF12540.8 RUS77488.1 - 0.027 14.6 3.5 0.075 13.2 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) Prominin PF05478.11 RUS77488.1 - 0.07 11.1 8.6 0.099 10.6 8.6 1.1 1 0 0 1 1 1 0 Prominin SLATT_1 PF18181.1 RUS77488.1 - 0.16 11.9 3.5 7.9 6.4 0.6 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 NPV_P10 PF05531.12 RUS77488.1 - 1.9 9.0 4.9 6.6 7.3 3.9 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS77488.1 - 3.1 8.1 5.0 12 6.2 3.9 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 RUS77488.1 - 9.9 4.5 8.5 11 4.4 0.9 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Arf PF00025.21 RUS77489.1 - 3.1e-50 170.0 0.1 3.4e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS77489.1 - 2e-13 50.6 0.1 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RUS77489.1 - 1.6e-10 40.7 0.5 4.9e-07 29.2 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RUS77489.1 - 8.4e-09 35.1 0.0 9.8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RUS77489.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 RUS77489.1 - 2.4e-08 33.7 0.1 2.9e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 RUS77489.1 - 0.00016 21.7 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RUS77489.1 - 0.0048 17.4 0.0 0.0058 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RUS77489.1 - 0.039 14.5 0.1 0.053 14.0 0.1 1.2 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 RUS77489.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RUS77489.1 - 0.14 11.6 0.8 0.55 9.7 0.8 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 RUS77489.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 RUS77489.1 - 0.17 11.7 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS77489.1 - 0.19 12.1 0.2 0.31 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain Glyco_tran_28_C PF04101.16 RUS77490.1 - 2.4e-27 96.0 0.0 2.9e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NAD_binding_5 PF07994.12 RUS77491.1 - 1.2e-141 471.8 0.0 1.5e-141 471.5 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 RUS77491.1 - 3.6e-48 162.3 0.2 7.3e-48 161.3 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TMF_TATA_bd PF12325.8 RUS77491.1 - 0.11 12.7 0.4 0.26 11.5 0.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MORN PF02493.20 RUS77492.1 - 0.00088 19.0 8.7 16 5.6 0.1 4.4 4 0 0 4 4 4 4 MORN repeat Toxin_4 PF00706.17 RUS77492.1 - 0.026 14.9 1.8 1.1e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Anenome neurotoxin DUF1882 PF08966.11 RUS77492.1 - 0.084 13.1 0.2 2.8e+02 1.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1882) DUF5351 PF17302.2 RUS77492.1 - 0.43 10.8 8.4 1e+02 3.2 0.1 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5351) S10_plectin PF03501.15 RUS77493.1 - 6.7e-45 151.1 0.1 8.1e-45 150.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF1495 PF07381.11 RUS77493.1 - 0.17 11.7 0.1 0.85 9.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) DHHC PF01529.20 RUS77494.1 - 4.1e-26 91.7 15.0 7.5e-26 90.8 15.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase MRAP PF15183.6 RUS77494.1 - 1.5 8.8 4.5 1 9.3 1.0 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DHHC PF01529.20 RUS77495.1 - 7.9e-28 97.2 6.5 1.1e-27 96.8 6.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DHHC PF01529.20 RUS77496.1 - 1.4e-22 80.3 14.8 2.1e-22 79.7 14.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2632 PF10943.8 RUS77497.1 - 0.08 12.5 0.1 0.088 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) C1q PF00386.21 RUS77498.1 - 9.8e-08 32.3 0.0 2.4e-07 31.0 0.0 1.6 2 0 0 2 2 1 1 C1q domain BrkDBD PF09607.10 RUS77498.1 - 0.00045 19.9 0.7 0.12 12.1 0.1 2.6 2 0 0 2 2 2 1 Brinker DNA-binding domain ADIP PF11559.8 RUS77498.1 - 0.00048 20.2 8.1 0.00089 19.4 8.1 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 RUS77498.1 - 0.0033 17.7 7.2 0.0051 17.0 7.2 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Syntaxin PF00804.25 RUS77498.1 - 0.015 14.9 1.5 0.015 14.9 1.5 1.7 2 0 0 2 2 2 0 Syntaxin ZapB PF06005.12 RUS77498.1 - 0.018 15.4 3.2 0.051 14.0 3.2 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Vac_Fusion PF02346.16 RUS77498.1 - 0.019 14.6 1.6 1.9 8.2 0.3 2.5 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF3450 PF11932.8 RUS77498.1 - 0.019 14.3 2.5 0.028 13.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 RUS77498.1 - 0.026 15.1 7.8 0.051 14.1 7.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 RUS77498.1 - 0.04 14.4 10.5 0.47 11.0 1.7 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS77498.1 - 0.042 14.1 4.1 0.08 13.2 2.0 2.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) YscO PF07321.12 RUS77498.1 - 0.056 13.4 4.9 0.1 12.5 4.9 1.5 1 1 0 1 1 1 0 Type III secretion protein YscO XRCC4 PF06632.12 RUS77498.1 - 0.071 11.9 6.2 0.033 13.1 4.2 1.4 2 0 0 2 2 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 EzrA PF06160.12 RUS77498.1 - 0.084 11.0 6.5 0.11 10.6 6.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3552 PF12072.8 RUS77498.1 - 0.091 12.2 4.7 0.15 11.5 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SOGA PF11365.8 RUS77498.1 - 0.13 13.4 5.9 1.5 10.0 0.9 2.4 1 1 1 2 2 2 0 Protein SOGA bZIP_2 PF07716.15 RUS77498.1 - 0.17 12.0 1.0 0.53 10.4 1.0 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Spc7 PF08317.11 RUS77498.1 - 0.19 10.6 6.9 0.07 12.0 3.9 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 RUS77498.1 - 0.2 12.0 2.0 0.23 11.8 1.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.11 RUS77498.1 - 0.21 10.4 6.9 0.26 10.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.12 RUS77498.1 - 0.22 12.1 4.0 4.7 7.9 1.7 2.8 2 1 0 2 2 2 0 SlyX Phage_GPO PF05929.11 RUS77498.1 - 0.22 11.1 2.4 0.28 10.7 2.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF641 PF04859.12 RUS77498.1 - 0.25 11.7 2.9 0.5 10.7 2.9 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) YabA PF06156.13 RUS77498.1 - 0.26 11.9 5.3 0.17 12.5 3.2 1.8 1 1 1 2 2 1 0 Initiation control protein YabA BRE1 PF08647.11 RUS77498.1 - 0.47 10.6 7.9 0.46 10.6 2.5 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4164 PF13747.6 RUS77498.1 - 0.53 10.6 5.5 0.47 10.8 3.2 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 RUS77498.1 - 0.53 10.3 6.5 0.36 10.9 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 RUS77498.1 - 0.59 10.6 4.1 0.98 9.9 3.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 EMP24_GP25L PF01105.24 RUS77498.1 - 0.63 10.0 3.6 4.7 7.1 0.0 2.5 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD bZIP_1 PF00170.21 RUS77498.1 - 0.67 10.1 3.7 0.32 11.1 1.0 1.9 2 0 0 2 2 1 0 bZIP transcription factor Sec34 PF04136.15 RUS77498.1 - 0.79 9.6 8.5 6.6 6.6 5.6 3.0 1 1 3 4 4 4 0 Sec34-like family BAG PF02179.16 RUS77498.1 - 0.89 10.0 5.6 1.1 9.8 1.1 2.4 2 0 0 2 2 2 0 BAG domain Rootletin PF15035.6 RUS77498.1 - 1.1 9.3 13.3 1.7 8.6 13.3 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 RUS77498.1 - 1.1 9.4 8.4 1.8 8.7 7.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 RUS77498.1 - 3.4 8.1 8.3 0.67 10.4 3.4 2.3 1 1 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.12 RUS77498.1 - 3.5 7.6 12.4 0.24 11.4 5.7 2.3 2 1 1 3 3 3 0 Laminin Domain II C1q PF00386.21 RUS77499.1 - 1.3e-08 35.1 0.1 4.9e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 C1q domain SHE3 PF17078.5 RUS77499.1 - 0.014 15.2 18.9 0.032 13.9 17.4 1.9 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 SKA2 PF16740.5 RUS77499.1 - 0.026 14.3 18.1 1.6 8.6 1.2 3.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 TMF_TATA_bd PF12325.8 RUS77499.1 - 0.064 13.5 19.5 0.15 12.3 8.2 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ANAPC5 PF12862.7 RUS77499.1 - 0.09 12.9 3.1 6.3 6.9 3.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF948 PF06103.11 RUS77499.1 - 0.16 12.2 3.0 0.3 11.4 2.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.13 RUS77499.1 - 0.32 9.6 5.2 0.3 9.7 4.0 1.4 1 1 0 1 1 1 0 Tweety RPW8 PF05659.11 RUS77499.1 - 0.76 9.5 12.2 3.5 7.3 0.5 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3450 PF11932.8 RUS77499.1 - 0.98 8.7 18.9 1.5 8.1 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 RUS77499.1 - 0.99 9.2 16.1 0.052 13.4 8.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 RUS77499.1 - 1.7 9.2 5.2 13 6.4 4.5 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RUS77499.1 - 3.1 7.9 8.4 2 8.5 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 RUS77499.1 - 3.5 7.7 23.5 0.092 12.8 6.3 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain GAS PF13851.6 RUS77499.1 - 3.5 6.9 24.4 0.37 10.1 8.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Blo-t-5 PF11642.8 RUS77499.1 - 3.9 7.5 12.9 1.2 9.1 5.3 3.0 1 1 1 2 2 2 0 Mite allergen Blo t 5 FlxA PF14282.6 RUS77499.1 - 4.4 7.4 17.1 0.22 11.5 8.2 2.8 1 1 1 2 2 2 0 FlxA-like protein Bap31_Bap29_C PF18035.1 RUS77499.1 - 5.9 7.0 11.4 69 3.6 6.8 3.4 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF573 PF04504.14 RUS77499.1 - 6.3 7.5 13.0 8.6 7.1 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Fib_alpha PF08702.10 RUS77499.1 - 7.6 6.7 14.2 2.6 8.2 9.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 RUS77499.1 - 9.4 6.5 18.2 0.21 11.8 8.0 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 RUS77500.1 - 0.0015 19.0 1.5 0.0016 18.9 0.6 1.4 2 0 0 2 2 2 1 Protein of unknown function DUF16 BBS2_C PF14782.6 RUS77500.1 - 0.058 12.1 0.6 0.52 9.0 0.3 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF724 PF05266.14 RUS77500.1 - 0.061 13.1 0.7 0.11 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2312 PF10073.9 RUS77500.1 - 0.087 12.5 1.4 7.1 6.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) LRRFIP PF09738.9 RUS77500.1 - 0.15 11.5 6.3 0.066 12.7 2.5 1.9 2 0 0 2 2 2 0 LRRFIP family DUF3450 PF11932.8 RUS77500.1 - 1.2 8.3 8.8 0.35 10.2 4.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Nbl1_Borealin_N PF10444.9 RUS77500.1 - 6.6 6.5 6.3 27 4.5 0.2 2.9 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal Ig_3 PF13927.6 RUS77502.1 - 3.2e-05 24.4 0.0 0.00065 20.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS77502.1 - 9.7e-05 22.6 0.2 0.0046 17.3 0.1 2.3 1 1 1 2 2 2 1 Immunoglobulin domain EB PF01683.18 RUS77502.1 - 1.3 9.4 8.2 4.3 7.7 8.2 1.9 1 1 0 1 1 1 0 EB module EB PF01683.18 RUS77503.1 - 3.5e-06 27.2 2.0 4.7e-06 26.8 2.0 1.2 1 0 0 1 1 1 1 EB module DUF1344 PF07076.11 RUS77503.1 - 0.00034 20.5 0.0 27 4.8 0.0 4.4 1 1 6 7 7 7 0 Protein of unknown function (DUF1344) MspA PF09203.11 RUS77503.1 - 0.0064 16.4 1.9 0.55 10.1 0.2 3.4 1 1 1 2 2 2 1 MspA Laminin_EGF PF00053.24 RUS77503.1 - 0.031 14.4 4.2 0.064 13.4 4.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 RUS77503.1 - 0.079 13.4 7.7 0.17 12.3 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain NAD2 PF18782.1 RUS77503.1 - 2.4 8.2 5.3 3.3 7.8 0.1 3.1 1 1 2 4 4 4 0 Novel AID APOBEC clade 2 TMP PF05017.14 RUS77503.1 - 5.5 8.1 14.5 1.9e+02 3.6 0.0 6.6 6 0 0 6 6 6 0 TMP repeat DUF3794 PF12673.7 RUS77504.1 - 0.044 14.1 0.0 1.6e+02 2.6 0.0 4.9 2 2 2 5 5 5 0 Domain of unknown function (DUF3794) Ig_2 PF13895.6 RUS77505.1 - 3.3e-05 24.1 0.9 0.0046 17.3 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS77505.1 - 0.00097 19.3 3.2 0.0015 18.6 1.4 2.1 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 RUS77505.1 - 0.0017 18.9 0.5 0.0046 17.5 0.2 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_4 PF16680.5 RUS77505.1 - 0.0049 17.1 0.3 0.014 15.7 0.1 1.7 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS77505.1 - 0.0086 16.5 0.1 0.013 15.9 0.1 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain RNase_H PF00075.24 RUS77506.1 - 2.5e-17 63.4 0.4 1.3e-16 61.1 0.4 2.1 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS77506.1 - 0.00025 20.9 0.1 0.00061 19.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like NodZ PF05830.11 RUS77506.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) YmgB PF10798.8 RUS77506.1 - 0.035 13.9 0.2 6.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Synaptobrevin PF00957.21 RUS77507.1 - 1.7e-30 104.6 1.9 2.6e-30 104.0 1.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RUS77507.1 - 3e-13 49.6 0.0 5.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain EMP24_GP25L PF01105.24 RUS77507.1 - 0.0004 20.4 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 RUS77507.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Integrase_H2C2 PF17921.1 RUS77507.1 - 0.0061 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain CD34_antigen PF06365.12 RUS77507.1 - 0.062 12.9 0.3 0.097 12.2 0.3 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family ODV-E18 PF10717.9 RUS77507.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Dynactin PF12455.8 RUS77507.1 - 0.13 11.5 0.3 0.16 11.2 0.3 1.1 1 0 0 1 1 1 0 Dynein associated protein RIFIN PF02009.16 RUS77507.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Rifin ASFV_J13L PF05568.11 RUS77507.1 - 0.18 11.6 4.8 0.22 11.3 3.8 1.5 2 0 0 2 2 2 0 African swine fever virus J13L protein T2SSF PF00482.23 RUS77507.1 - 6.4 6.8 5.6 47 3.9 5.6 2.1 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F SNARE PF05739.19 RUS77507.1 - 7 6.7 8.1 15 5.7 7.7 2.0 1 1 0 1 1 1 0 SNARE domain Mito_morph_reg PF14972.6 RUS77508.1 - 5.8e-69 230.8 0.0 6.5e-69 230.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator adh_short PF00106.25 RUS77509.1 - 1.7e-50 171.2 0.1 2.3e-50 170.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS77509.1 - 8.1e-36 123.7 0.1 1e-35 123.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS77509.1 - 3.4e-08 33.6 0.3 5.3e-08 33.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS77509.1 - 8.2e-06 25.4 0.2 2.2e-05 24.0 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 RUS77509.1 - 0.0013 18.8 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 RUS77509.1 - 0.0028 18.2 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 RUS77509.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 RUS77509.1 - 0.0056 16.5 0.2 0.073 12.9 0.1 2.6 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 RUS77509.1 - 0.0056 15.9 0.1 0.0085 15.3 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 RUS77509.1 - 0.018 15.0 0.1 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 RUS77509.1 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 RUS77509.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.22 RUS77510.1 - 2.8e-37 126.4 0.8 3.9e-19 68.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS77510.1 - 1.6e-13 50.6 0.2 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS77510.1 - 2.8e-08 33.6 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RUS77510.1 - 0.036 14.1 5.7 0.25 11.4 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif PHM7_cyt PF14703.6 RUS77510.1 - 0.12 12.6 3.5 2.7 8.2 0.3 3.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4637 PF15470.6 RUS77510.1 - 5 6.8 9.0 15 5.2 8.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) zf-RING_2 PF13639.6 RUS77511.1 - 3.4e-14 52.9 6.8 5.2e-14 52.3 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS77511.1 - 1.2e-09 37.8 6.7 1.9e-09 37.2 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS77511.1 - 1.3e-09 37.6 2.6 2.6e-09 36.6 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 RUS77511.1 - 3.4e-09 36.9 6.7 8.7e-09 35.5 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS77511.1 - 5.8e-09 35.7 6.1 9.2e-09 35.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS77511.1 - 5.6e-07 29.4 3.8 8.6e-07 28.8 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RUS77511.1 - 3.1e-06 27.1 1.0 5.9e-06 26.2 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RUS77511.1 - 4.6e-06 26.4 4.4 8.8e-06 25.5 4.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS77511.1 - 1.2e-05 25.3 2.6 1.2e-05 25.3 2.6 1.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS77511.1 - 0.00011 22.0 6.8 0.0017 18.2 7.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RUS77511.1 - 0.0057 16.3 1.5 0.011 15.4 1.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 RUS77511.1 - 0.0068 16.2 3.9 0.013 15.2 3.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RUS77511.1 - 0.016 15.4 4.2 0.064 13.4 4.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 RUS77511.1 - 0.019 14.8 3.4 1.9 8.4 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.7 RUS77511.1 - 0.034 14.3 2.1 0.087 13.0 2.1 1.7 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 RUS77511.1 - 0.096 12.6 3.1 1.6 8.7 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UBZ_FAAP20 PF15750.5 RUS77511.1 - 0.58 10.2 4.6 0.8 9.7 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-C3HC4_4 PF15227.6 RUS77511.1 - 1.6 8.9 6.1 5 7.4 6.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 RUS77511.1 - 3.3 8.3 8.0 4.9 7.7 0.2 2.9 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain DUF4201 PF13870.6 RUS77512.1 - 1e-25 90.5 19.5 6.8e-17 61.8 11.2 3.8 2 2 1 3 3 3 2 Domain of unknown function (DUF4201) SH2 PF00017.24 RUS77513.1 - 1.2e-07 31.8 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 RUS77513.1 - 2.4e-07 31.0 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 SOCS box SDA1 PF05285.12 RUS77515.1 - 5.1e-06 26.1 29.0 5.3e-06 26.1 29.0 1.1 1 0 0 1 1 1 1 SDA1 V_ATPase_I PF01496.19 RUS77515.1 - 5.2e-05 21.4 3.7 6.8e-05 21.0 3.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BUD22 PF09073.10 RUS77515.1 - 8.9e-05 22.0 21.4 8.9e-05 22.0 21.4 1.1 1 0 0 1 1 1 1 BUD22 CBP_BcsG PF11658.8 RUS77515.1 - 0.0039 15.7 0.0 0.0044 15.5 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG Pex24p PF06398.11 RUS77515.1 - 0.0083 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PHO4 PF01384.20 RUS77515.1 - 0.016 14.2 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family SAPS PF04499.15 RUS77515.1 - 0.046 12.5 8.2 0.051 12.4 8.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4834 PF16118.5 RUS77515.1 - 0.067 14.2 0.3 0.22 12.5 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) PDR_CDR PF06422.12 RUS77515.1 - 0.14 12.0 0.6 0.27 11.2 0.6 1.4 1 0 0 1 1 1 0 CDR ABC transporter Amnionless PF14828.6 RUS77515.1 - 0.14 10.9 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 RUS77515.1 - 0.45 11.4 5.0 26 5.8 5.0 2.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Anoctamin PF04547.12 RUS77515.1 - 0.57 9.0 5.5 0.72 8.6 5.5 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Nop14 PF04147.12 RUS77515.1 - 1.2 7.3 44.4 1.4 7.1 44.4 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane_5 PF13346.6 RUS77515.1 - 1.2 8.6 30.5 1.9 8.0 30.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF747 PF05346.11 RUS77515.1 - 1.2 8.5 13.2 1.6 8.2 13.2 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family SUR7 PF06687.12 RUS77515.1 - 1.7 8.2 3.3 2.2 7.9 3.3 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2244 PF10003.9 RUS77515.1 - 3.7 7.2 11.6 6.4 6.4 11.6 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) CobT PF06213.12 RUS77515.1 - 4 6.7 38.2 7.2 5.9 38.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GPI2 PF06432.11 RUS77515.1 - 4.4 6.7 15.6 5.9 6.2 15.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase G3P_acyltransf PF02660.15 RUS77515.1 - 8.6 6.4 13.3 12 6.0 13.3 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Methyltransf_11 PF08241.12 RUS77516.1 - 9.6e-48 160.8 0.1 3.3e-15 56.5 0.0 5.5 4 1 0 4 4 4 4 Methyltransferase domain Methyltransf_25 PF13649.6 RUS77516.1 - 3.8e-46 155.7 0.0 1.4e-15 57.8 0.0 5.7 4 1 0 4 4 4 3 Methyltransferase domain Methyltransf_31 PF13847.6 RUS77516.1 - 9.5e-25 87.2 0.0 1.3e-08 34.8 0.0 5.0 3 2 0 3 3 3 3 Methyltransferase domain Methyltransf_15 PF09445.10 RUS77516.1 - 2.1e-19 69.7 0.5 3.2e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 RUS77516.1 - 1.4e-17 64.0 0.0 0.00011 22.1 0.0 3.4 3 0 0 3 3 3 3 Methyltransferase domain Ubie_methyltran PF01209.18 RUS77516.1 - 3.9e-17 62.4 0.0 0.00026 20.4 0.0 5.1 4 1 1 5 5 5 3 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS77516.1 - 1.8e-16 60.7 0.0 0.00041 21.0 0.0 5.1 4 1 1 5 5 5 3 Methyltransferase domain ADH_zinc_N PF00107.26 RUS77516.1 - 3.9e-14 52.7 0.2 0.0055 16.7 0.0 5.2 6 1 1 7 7 6 4 Zinc-binding dehydrogenase MTS PF05175.14 RUS77516.1 - 1.5e-13 50.7 0.0 0.0061 16.1 0.0 5.2 3 2 2 5 5 5 3 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 RUS77516.1 - 4.6e-11 42.3 0.3 0.019 14.0 0.0 3.1 3 0 0 3 3 3 3 tRNA (Uracil-5-)-methyltransferase LZ3wCH PF18517.1 RUS77516.1 - 3e-10 40.1 0.4 0.026 14.6 0.0 4.0 3 0 0 3 3 3 3 Leucine zipper with capping helix domain N6_N4_Mtase PF01555.18 RUS77516.1 - 4.9e-10 39.5 0.0 0.055 13.2 0.0 4.7 3 1 1 4 4 4 3 DNA methylase TPMT PF05724.11 RUS77516.1 - 5.8e-10 39.2 0.0 0.08 12.6 0.0 3.4 3 0 0 3 3 3 3 Thiopurine S-methyltransferase (TPMT) RVT_1 PF00078.27 RUS77516.1 - 1.1e-09 38.2 0.0 3.8e-09 36.4 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_8 PF05148.15 RUS77516.1 - 6e-09 36.1 0.0 0.56 10.0 0.0 4.2 3 1 1 4 4 4 3 Hypothetical methyltransferase PrmA PF06325.13 RUS77516.1 - 1.4e-08 34.5 0.0 0.097 12.0 0.0 3.3 3 0 0 3 3 3 3 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 RUS77516.1 - 6.1e-08 32.3 0.0 1.1 8.7 0.0 4.7 5 0 0 5 5 5 3 Putative methyltransferase DUF4318 PF14201.6 RUS77516.1 - 7.4e-07 29.6 1.3 1.8 9.1 0.0 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4318) Methyltransf_29 PF03141.16 RUS77516.1 - 1.1e-06 27.5 0.1 1.3 7.5 0.0 5.0 3 2 2 5 5 5 2 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 RUS77516.1 - 6.2e-06 26.1 0.0 1.4 8.7 0.0 3.5 3 1 0 3 3 3 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5334 PF17268.2 RUS77516.1 - 0.00015 22.0 0.0 24 5.3 0.0 4.4 3 1 1 4 4 4 0 Family of unknown function (DUF5334) AviRa PF11599.8 RUS77516.1 - 0.0022 17.5 0.1 5.2 6.5 0.0 3.2 3 0 0 3 3 3 1 RRNA methyltransferase AviRa RrnaAD PF00398.20 RUS77516.1 - 0.015 14.4 0.0 24 3.9 0.0 3.2 3 0 0 3 3 3 0 Ribosomal RNA adenine dimethylase Rad21_Rec8 PF04824.16 RUS77516.1 - 0.025 13.9 0.9 25 4.3 0.0 3.3 3 0 0 3 3 3 0 Conserved region of Rad21 / Rec8 like protein V4R PF02830.18 RUS77516.1 - 0.11 12.6 2.1 34 4.5 0.0 4.1 4 0 0 4 4 4 0 V4R domain UBA_6 PF18039.1 RUS77516.1 - 0.15 12.0 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 UBA-like domain ROKNT PF08067.11 RUS77516.1 - 0.17 12.2 8.1 11 6.4 0.3 3.6 3 0 0 3 3 3 0 ROKNT (NUC014) domain Vac_Fusion PF02346.16 RUS77516.1 - 0.25 11.0 0.8 6.1 6.6 0.0 3.2 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 BID PF06393.11 RUS77516.1 - 1.4 8.4 4.0 23 4.5 0.1 3.0 3 0 0 3 3 3 0 BH3 interacting domain (BID) Methyltransf_25 PF13649.6 RUS77517.1 - 1e-16 61.4 0.0 4.1e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS77517.1 - 2.3e-16 60.2 0.0 5.6e-16 59.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS77517.1 - 2.2e-09 37.3 0.0 3.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS77517.1 - 1.2e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS77517.1 - 3.4e-06 27.7 0.0 6.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RUS77517.1 - 6.6e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 RUS77517.1 - 0.00047 19.6 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 RUS77517.1 - 0.0024 17.5 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 RUS77517.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 RUS77517.1 - 0.015 15.3 0.0 0.066 13.2 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TPMT PF05724.11 RUS77517.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 RUS77517.1 - 0.044 13.2 0.0 0.46 9.9 0.0 2.5 3 0 0 3 3 3 0 Putative methyltransferase DUF4318 PF14201.6 RUS77517.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) Methyltransf_29 PF03141.16 RUS77517.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase LRR19-TM PF15176.6 RUS77518.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.0 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain TFIIA PF03153.13 RUS77518.1 - 0.36 10.8 30.4 0.44 10.5 30.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAP17 PF15807.5 RUS77518.1 - 1.3 9.3 3.8 0.89 9.8 0.2 2.2 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 RUS77518.1 - 5.2 8.1 9.1 1.1e+02 3.8 9.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) STG PF15809.5 RUS77519.1 - 1.2 9.2 25.2 19 5.2 0.7 5.0 1 1 5 6 6 6 0 Simian taste bud-specific gene product family SieB PF14163.6 RUS77520.1 - 0.11 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Pkinase PF00069.25 RUS77521.1 - 7.6e-68 228.7 0.0 9.2e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77521.1 - 7.8e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS77521.1 - 3e-08 33.3 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS77521.1 - 0.0023 16.9 0.1 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain UCH PF00443.29 RUS77522.1 - 2.8e-43 148.3 0.1 7.6e-43 146.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS77522.1 - 1.8e-30 106.7 2.2 2.5e-30 106.2 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 RUS77522.1 - 5.5e-08 32.6 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 RUS77522.1 - 0.021 14.6 0.7 0.059 13.1 0.7 1.9 1 0 0 1 1 1 0 Ubiquitin family RT_RNaseH_2 PF17919.1 RUS77523.1 - 6.8e-32 109.5 0.0 1.6e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS77523.1 - 5.5e-31 107.0 0.0 1.1e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77523.1 - 2.6e-22 79.5 0.0 3.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBM_17_28 PF03424.14 RUS77523.1 - 0.046 13.4 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 17/28) Ofd1_CTDD PF10637.9 RUS77524.1 - 3.4e-35 121.6 0.1 1.4e-32 113.1 0.0 3.1 3 0 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 RUS77524.1 - 3.7e-32 110.9 0.1 5.4e-26 91.1 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RUS77524.1 - 2.6e-16 60.3 0.0 5.4e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily ELO PF01151.18 RUS77525.1 - 1.5e-46 159.0 30.5 3.4e-46 157.8 30.5 1.5 1 1 0 1 1 1 1 GNS1/SUR4 family Lactamase_B PF00753.27 RUS77527.1 - 7e-17 62.1 0.2 8.2e-16 58.6 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS77527.1 - 0.00041 19.9 0.1 0.00085 18.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 RUS77528.1 - 1.9e-23 83.0 30.5 3.5e-17 62.4 9.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fibrinogen_C PF00147.18 RUS77530.1 - 6e-54 183.2 7.7 6e-54 183.2 7.7 1.6 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS77530.1 - 0.0015 18.4 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 RUS77530.1 - 0.024 14.9 2.0 0.024 14.9 2.0 2.8 1 1 2 3 3 3 0 ABC transporter C-terminal domain Csa1 PF06023.12 RUS77530.1 - 0.047 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 MCU PF04678.13 RUS77530.1 - 0.087 12.9 2.1 0.099 12.7 1.1 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter BLOC1_2 PF10046.9 RUS77530.1 - 0.095 13.0 14.0 0.11 12.8 0.9 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 RUS77530.1 - 0.11 12.4 7.5 0.81 9.7 4.3 3.2 2 1 0 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.9 RUS77530.1 - 0.13 11.1 8.1 0.047 12.6 4.7 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain OmpH PF03938.14 RUS77530.1 - 0.15 12.4 3.4 0.26 11.6 3.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 RUS77530.1 - 0.15 12.5 8.9 0.66 10.5 6.5 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 RUS77530.1 - 0.16 11.6 9.5 0.071 12.8 4.4 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF2730 PF10805.8 RUS77530.1 - 0.32 11.1 5.3 0.6 10.2 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FapA PF03961.13 RUS77530.1 - 0.35 9.4 7.1 0.39 9.3 6.4 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Hemagglutinin PF00509.18 RUS77530.1 - 0.39 9.1 9.3 0.11 10.8 5.8 1.7 1 1 1 2 2 2 0 Haemagglutinin CCDC53 PF10152.9 RUS77530.1 - 0.53 10.7 7.5 1.5 9.3 2.0 2.4 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Matrilin_ccoil PF10393.9 RUS77530.1 - 0.64 9.9 3.7 4.7 7.2 0.1 3.2 1 1 2 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF5446 PF17522.2 RUS77530.1 - 0.7 10.1 6.2 0.2 11.8 0.6 2.7 1 1 1 3 3 3 0 Family of unknown function (DUF5446) Baculo_PEP_C PF04513.12 RUS77530.1 - 0.7 9.9 12.6 1.9 8.6 7.1 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad4 PF08650.10 RUS77530.1 - 0.82 9.7 4.8 0.78 9.8 0.6 2.6 1 1 1 2 2 2 0 DASH complex subunit Dad4 CFC PF09443.10 RUS77530.1 - 0.95 9.4 3.8 1.8 8.5 3.8 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) FlaC_arch PF05377.11 RUS77530.1 - 1.4 9.4 9.0 4.2 7.8 1.0 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) RPW8 PF05659.11 RUS77530.1 - 1.6 8.4 11.5 0.097 12.4 1.3 2.7 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DHR10 PF18595.1 RUS77530.1 - 4.1 7.5 8.2 6 7.0 5.2 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 RUS77530.1 - 4.4 7.4 10.2 2 8.4 4.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RUS77530.1 - 7.7 6.7 10.5 9.2 6.4 6.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fibrinogen_C PF00147.18 RUS77531.1 - 4.7e-56 190.1 4.1 7.5e-56 189.4 4.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TMF_DNA_bd PF12329.8 RUS77531.1 - 0.054 13.5 1.6 0.14 12.2 1.6 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 RUS77531.1 - 0.073 12.1 0.6 0.098 11.7 0.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PIN_8 PF18476.1 RUS77531.1 - 0.12 12.3 2.8 0.21 11.4 2.8 1.5 1 1 0 1 1 1 0 PIN like domain NPV_P10 PF05531.12 RUS77531.1 - 0.27 11.7 7.5 0.058 13.9 2.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 RUS77531.1 - 0.33 10.5 5.3 0.52 9.9 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ABC_tran_CTD PF16326.5 RUS77531.1 - 0.51 10.6 3.6 2.2 8.6 2.8 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 RUS77531.1 - 5.7 7.0 9.8 7.5 6.6 2.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APOBEC1 PF18769.1 RUS77532.1 - 0.89 9.8 2.5 17 5.7 0.2 2.8 1 1 0 2 2 2 0 APOBEC1 Fibrinogen_C PF00147.18 RUS77533.1 - 4.7e-59 199.9 5.9 7.1e-59 199.3 5.9 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS77533.1 - 0.0004 20.4 17.8 0.0049 16.9 3.8 3.0 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 RUS77533.1 - 0.00045 20.3 12.3 0.23 11.6 4.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 RUS77533.1 - 0.0011 19.2 16.4 0.28 11.4 2.2 4.1 1 1 2 4 4 4 2 ABC transporter C-terminal domain NPV_P10 PF05531.12 RUS77533.1 - 0.0033 17.9 14.0 0.037 14.5 0.4 3.0 2 1 0 3 3 2 2 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 RUS77533.1 - 0.011 13.4 10.3 0.014 12.9 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 RUS77533.1 - 0.012 15.9 5.7 0.012 15.9 5.7 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 RUS77533.1 - 0.014 15.7 18.3 0.65 10.3 2.8 3.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_N PF15905.5 RUS77533.1 - 0.033 13.7 17.9 0.048 13.1 17.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 RUS77533.1 - 0.042 14.0 18.0 0.11 12.7 7.6 2.6 1 1 1 2 2 2 0 Tropomyosin like Med9 PF07544.13 RUS77533.1 - 0.089 12.9 9.5 1.8 8.7 0.5 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 RUS77533.1 - 0.1 12.7 14.2 1.3 9.1 1.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-ZPR1 PF03367.13 RUS77533.1 - 0.11 12.4 7.4 0.14 12.0 4.3 2.3 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF211 PF02680.14 RUS77533.1 - 0.12 12.5 2.3 0.75 10.0 1.1 2.7 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 Phasin PF05597.11 RUS77533.1 - 0.17 11.9 7.6 2.8 8.0 0.5 3.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlaC_arch PF05377.11 RUS77533.1 - 0.18 12.2 18.9 5.7 7.4 2.1 4.8 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 RUS77533.1 - 0.23 11.6 4.0 0.42 10.7 1.2 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 RUS77533.1 - 0.37 10.8 15.5 3.5 7.7 1.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 RUS77533.1 - 0.38 11.3 10.8 1.9 9.0 4.0 2.6 1 1 1 2 2 2 0 Spectrin repeat TRAF_BIRC3_bd PF16673.5 RUS77533.1 - 0.39 10.5 6.5 5.3 6.9 2.0 3.4 1 1 2 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Prefoldin_2 PF01920.20 RUS77533.1 - 0.51 10.3 16.6 15 5.6 1.5 3.9 1 1 2 3 3 3 0 Prefoldin subunit XhlA PF10779.9 RUS77533.1 - 0.81 9.9 26.2 0.42 10.9 2.5 4.3 2 1 2 4 4 4 0 Haemolysin XhlA DUF4407 PF14362.6 RUS77533.1 - 0.98 8.7 7.8 4.3 6.6 7.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC53 PF10152.9 RUS77533.1 - 1.6 9.1 14.1 10 6.5 6.0 3.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex WXG100 PF06013.12 RUS77533.1 - 1.7 8.9 5.4 3.6 7.9 0.4 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Matrilin_ccoil PF10393.9 RUS77533.1 - 2 8.3 12.8 4.1 7.3 0.1 4.7 3 3 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin RPW8 PF05659.11 RUS77533.1 - 2.3 7.9 16.4 1 9.0 2.1 3.6 2 1 2 4 4 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 UPF0184 PF03670.13 RUS77533.1 - 2.8 8.4 8.3 1 9.8 1.4 2.8 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Viral_P18 PF04521.13 RUS77533.1 - 3.7 7.3 9.4 1.4 8.7 0.5 3.2 2 1 2 4 4 3 0 ssRNA positive strand viral 18kD cysteine rich protein HSBP1 PF06825.12 RUS77533.1 - 5.6 6.9 17.1 5.5 6.9 2.7 4.2 1 1 1 3 3 3 0 Heat shock factor binding protein 1 Tweety PF04906.13 RUS77533.1 - 7.3 5.1 7.1 1.7 7.3 0.8 2.1 1 1 0 2 2 2 0 Tweety Lipocalin PF00061.23 RUS77534.1 - 3.4e-06 27.3 0.7 4.6e-06 26.9 0.7 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS77534.1 - 0.0059 16.5 0.3 0.0088 16.0 0.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family E3_UFM1_ligase PF09743.9 RUS77535.1 - 3.2e-104 348.3 1.4 5.3e-104 347.6 1.4 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 PIP49_C PF12260.8 RUS77536.1 - 0.00014 21.5 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 RUS77536.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 RUS77536.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain FAM198 PF15051.6 RUS77536.1 - 0.09 11.6 0.0 0.24 10.2 0.0 1.7 1 0 0 1 1 1 0 FAM198 protein Tim29 PF10171.9 RUS77538.1 - 0.0063 16.0 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 Translocase of the Inner Mitochondrial membrane 29 CsbD PF05532.12 RUS77538.1 - 0.027 14.4 0.8 2.1 8.3 0.2 3.5 3 0 0 3 3 3 0 CsbD-like DUF268 PF03269.14 RUS77538.1 - 0.036 13.9 0.2 8.7 6.2 0.0 2.6 2 1 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 YtxH PF12732.7 RUS77538.1 - 0.037 14.5 8.0 0.095 13.2 0.6 3.2 2 2 0 2 2 2 0 YtxH-like protein DUF1640 PF07798.11 RUS77538.1 - 0.089 12.8 0.3 0.39 10.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Spore_GerAC PF05504.11 RUS77538.1 - 0.1 12.8 4.6 0.24 11.6 3.2 2.2 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Occludin_ELL PF07303.13 RUS77538.1 - 0.13 13.0 1.1 0.45 11.3 0.3 2.2 2 1 0 2 2 2 0 Occludin homology domain Sec31 PF11549.8 RUS77538.1 - 0.18 11.7 0.1 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein transport protein SEC31 Ribosomal_S13 PF00416.22 RUS77538.1 - 0.45 10.9 4.5 0.7 10.3 2.6 2.3 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF2120 PF09893.9 RUS77538.1 - 0.88 9.7 6.0 5.2 7.2 1.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) CelTOS PF18659.1 RUS77538.1 - 8.8 6.8 16.5 2.6 8.5 0.7 3.9 2 2 2 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites RRM_1 PF00076.22 RUS77540.1 - 1.7e-36 123.9 0.4 3e-17 62.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.14 RUS77540.1 - 7.6e-07 29.4 6.6 0.11 12.4 0.1 4.1 3 1 0 3 3 3 3 Suppressor of forked protein (Suf) RRM_occluded PF16842.5 RUS77540.1 - 1e-06 28.5 0.0 1.6e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Lsm_interact PF05391.11 RUS77540.1 - 4.2e-05 22.9 5.5 0.00021 20.7 5.5 2.3 1 0 0 1 1 1 1 Lsm interaction motif LSM_int_assoc PF16605.5 RUS77540.1 - 0.00012 22.1 3.5 0.00035 20.6 3.5 1.8 1 0 0 1 1 1 1 LSM-interacting associated unstructured RRM_3 PF08777.11 RUS77540.1 - 0.00054 20.0 0.5 0.014 15.4 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif NRDE-2 PF08424.10 RUS77540.1 - 0.00081 18.6 1.0 0.00081 18.6 1.0 4.1 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference RRM_7 PF16367.5 RUS77540.1 - 0.012 15.8 0.1 0.13 12.3 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif TPR_14 PF13428.6 RUS77540.1 - 0.35 11.8 11.2 72 4.6 0.2 5.8 4 2 3 7 7 7 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 RUS77541.1 - 3e-57 194.1 0.2 4.4e-57 193.5 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS77541.1 - 1.3e-33 115.5 1.2 2e-33 114.9 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 RUS77541.1 - 1.2e-06 28.1 0.3 6e-06 25.8 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 RUS77541.1 - 0.04 13.8 0.9 1.2 9.0 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyoxalase PF00903.25 RUS77542.1 - 3.5e-09 36.9 0.0 0.00056 20.1 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 RUS77542.1 - 0.0037 17.3 0.1 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 CppA N-terminal Glyoxalase_2 PF12681.7 RUS77542.1 - 0.062 13.2 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain GHMP_kinases_N PF00288.26 RUS77543.1 - 4.6e-18 65.2 0.7 4.2e-17 62.1 0.8 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RUS77543.1 - 1.4e-06 28.5 0.1 1.4e-06 28.5 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal SBDS_C PF09377.10 RUS77544.1 - 2.1e-34 118.0 0.5 2.1e-34 118.0 0.5 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 RUS77544.1 - 3.4e-32 110.4 0.4 6.1e-32 109.6 0.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3095 PF11294.8 RUS77544.1 - 0.0082 15.2 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) SLS PF14611.6 RUS77544.1 - 0.039 13.8 0.6 0.09 12.6 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Epiglycanin_TR PF05647.11 RUS77545.1 - 2.9e-11 43.1 31.2 0.00026 20.8 5.5 3.9 2 1 2 4 4 4 4 Tandem-repeating region of mucin, epiglycanin-like CHCH PF06747.13 RUS77545.1 - 0.13 12.4 1.2 11 6.2 0.1 3.0 2 0 0 2 2 2 0 CHCH domain fn3 PF00041.21 RUS77546.1 - 1.1e-74 246.8 0.3 5.7e-12 45.8 0.2 10.3 9 1 1 10 10 10 10 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS77546.1 - 1.3e-18 67.4 10.4 0.0051 17.3 0.2 8.6 7 2 1 8 8 8 6 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS77546.1 - 1.4e-11 44.6 0.0 0.28 11.5 0.0 7.5 7 1 1 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 RUS77546.1 - 3e-08 33.9 0.0 27 5.3 0.0 6.8 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) CBM_4_9 PF02018.17 RUS77546.1 - 0.0034 17.7 1.3 15 5.9 0.0 4.5 5 0 0 5 5 5 1 Carbohydrate binding domain fn3_2 PF16893.5 RUS77546.1 - 0.042 14.0 0.1 16 5.7 0.0 4.4 5 0 0 5 5 5 0 Fibronectin type III domain PhoD_N PF16655.5 RUS77546.1 - 0.091 13.3 0.1 16 6.1 0.0 4.5 5 1 1 6 6 6 0 PhoD-like phosphatase, N-terminal domain CDC45 PF02724.14 RUS77547.1 - 3.8e-06 25.5 26.5 4.5e-06 25.3 26.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 RUS77547.1 - 2.9e-05 22.5 25.0 3.2e-05 22.4 25.0 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS77547.1 - 0.0011 18.5 29.0 0.0011 18.4 29.0 1.1 1 0 0 1 1 1 1 SDA1 Nop53 PF07767.11 RUS77547.1 - 0.0079 15.6 13.9 0.011 15.1 13.9 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CENP-N PF05238.13 RUS77547.1 - 0.14 11.5 1.9 0.34 10.2 2.0 1.5 1 1 0 1 1 1 0 Kinetochore protein CHL4 like SpoIIIAH PF12685.7 RUS77547.1 - 0.44 10.3 4.1 0.51 10.1 4.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Rrn6 PF10214.9 RUS77547.1 - 0.86 8.0 9.2 1.1 7.6 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BUD22 PF09073.10 RUS77547.1 - 0.91 8.8 31.1 1.3 8.3 31.1 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 RUS77547.1 - 2.6 6.8 7.6 3.2 6.5 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 RUS77547.1 - 3.2 6.4 9.6 3.4 6.3 9.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FmiP_Thoc5 PF09766.9 RUS77547.1 - 6.1 6.0 6.6 10 5.3 6.6 1.4 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RRXRR PF14239.6 RUS77547.1 - 9 6.1 16.4 14 5.5 16.4 1.2 1 0 0 1 1 1 0 RRXRR protein Cnn_1N PF07989.11 RUS77550.1 - 0.0035 17.4 12.9 0.024 14.8 2.4 3.2 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 HAP1_N PF04849.13 RUS77550.1 - 0.0036 16.5 6.8 0.0036 16.5 6.8 2.7 2 1 1 3 3 3 1 HAP1 N-terminal conserved region Tektin PF03148.14 RUS77550.1 - 0.0055 15.5 12.5 0.012 14.4 7.8 2.3 1 1 1 2 2 2 1 Tektin family DUF4200 PF13863.6 RUS77550.1 - 0.011 16.2 13.3 0.1 13.0 13.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.8 RUS77550.1 - 0.014 15.5 7.7 0.014 15.5 7.7 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 RUS77550.1 - 0.014 14.7 15.1 0.46 9.8 11.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 RUS77550.1 - 0.014 14.9 15.2 0.64 9.5 13.6 2.6 1 1 1 2 2 2 0 Leucine zipper DUF1664 PF07889.12 RUS77550.1 - 0.017 15.2 8.9 0.16 12.0 3.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS77550.1 - 0.034 13.0 16.7 0.0068 15.3 12.6 1.8 2 1 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 RUS77550.1 - 0.05 13.8 13.0 0.038 14.2 10.8 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 RUS77550.1 - 0.062 12.9 4.1 0.084 12.4 4.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF713 PF05218.14 RUS77550.1 - 0.068 12.9 6.8 0.64 9.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF713) AAA_13 PF13166.6 RUS77550.1 - 0.08 11.6 7.0 0.056 12.1 5.2 1.5 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 RUS77550.1 - 0.097 13.2 0.8 0.097 13.2 0.8 2.5 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 RUS77550.1 - 0.1 12.6 16.9 0.31 11.1 0.6 3.8 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 RUS77550.1 - 0.18 11.6 14.7 1.1 9.0 4.3 3.9 2 1 2 4 4 4 0 Septum formation initiator ERM PF00769.19 RUS77550.1 - 0.2 11.4 12.3 0.33 10.7 12.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MAD PF05557.13 RUS77550.1 - 0.21 9.9 21.2 0.027 12.8 13.4 2.3 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF4795 PF16043.5 RUS77550.1 - 0.21 11.2 9.5 3.9 7.0 8.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) ABC_tran_Xtn PF12848.7 RUS77550.1 - 0.28 11.2 5.2 0.15 12.1 1.7 2.3 3 0 0 3 3 1 0 ABC transporter Atg14 PF10186.9 RUS77550.1 - 0.35 9.9 9.1 0.7 8.9 8.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 RUS77550.1 - 0.37 10.9 17.6 0.27 11.4 0.3 4.0 4 1 0 4 4 4 0 bZIP transcription factor DUF724 PF05266.14 RUS77550.1 - 0.39 10.5 12.7 0.12 12.1 6.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) KASH_CCD PF14662.6 RUS77550.1 - 0.42 10.4 19.8 0.055 13.3 10.3 2.6 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 RUS77550.1 - 0.43 9.9 4.6 0.64 9.3 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 RUS77550.1 - 0.49 8.9 6.2 5.1 5.6 6.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A LMBR1 PF04791.16 RUS77550.1 - 0.5 9.2 5.0 0.61 8.9 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ax_dynein_light PF10211.9 RUS77550.1 - 0.56 10.1 12.6 3.5 7.5 2.8 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain SKA1 PF07160.12 RUS77550.1 - 0.65 9.8 9.4 0.53 10.1 3.8 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ZapB PF06005.12 RUS77550.1 - 0.7 10.4 22.9 0.15 12.5 2.6 3.4 2 1 2 4 4 3 0 Cell division protein ZapB Vir_act_alpha_C PF10400.9 RUS77550.1 - 0.74 10.5 5.0 4.3 8.1 1.5 3.0 1 1 2 3 3 3 0 Virulence activator alpha C-term SlyX PF04102.12 RUS77550.1 - 0.94 10.1 16.8 0.32 11.6 5.4 4.2 2 1 3 5 5 4 0 SlyX Snapin_Pallidin PF14712.6 RUS77550.1 - 1.4 9.3 12.7 0.88 10.0 4.4 3.6 2 1 1 4 4 4 0 Snapin/Pallidin FAM76 PF16046.5 RUS77550.1 - 1.5 8.1 6.7 2.4 7.4 6.7 1.3 1 0 0 1 1 1 0 FAM76 protein DUF2681 PF10883.8 RUS77550.1 - 1.9 8.9 12.4 0.28 11.6 1.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF1043 PF06295.12 RUS77550.1 - 2 8.4 10.6 8.5 6.4 3.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) CENP-F_leu_zip PF10473.9 RUS77550.1 - 2.4 8.2 22.7 0.86 9.6 15.8 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 RUS77550.1 - 3.6 6.8 8.8 1 8.5 4.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF3450 PF11932.8 RUS77550.1 - 3.7 6.8 16.6 0.1 11.9 7.0 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 RUS77550.1 - 4.1 7.4 12.6 6.2 6.8 8.7 2.8 1 1 2 3 3 3 0 Laminin Domain II DUF641 PF04859.12 RUS77550.1 - 4.6 7.6 9.7 1.2 9.5 5.5 2.3 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) Muted PF14942.6 RUS77550.1 - 5 7.4 13.1 1.9 8.8 7.0 2.6 1 1 3 4 4 4 0 Organelle biogenesis, Muted-like protein KxDL PF10241.9 RUS77550.1 - 7 7.0 9.8 1.9 8.8 3.0 3.2 2 1 2 4 4 4 0 Uncharacterized conserved protein COG2 PF06148.11 RUS77550.1 - 9.1 6.4 10.0 9.2 6.4 7.6 2.2 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HIP1_clath_bdg PF16515.5 RUS77550.1 - 9.3 6.9 16.1 1.9 9.2 8.1 3.2 2 2 2 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 I-set PF07679.16 RUS77552.1 - 2.8e-70 232.4 6.4 5.3e-17 61.7 0.0 8.2 7 2 2 9 9 9 6 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77552.1 - 7.2e-63 209.2 15.3 5.9e-16 58.8 0.0 8.0 7 1 1 8 8 8 6 Immunoglobulin domain Ig_2 PF13895.6 RUS77552.1 - 3.2e-44 149.1 5.6 1.1e-11 44.9 0.0 6.8 6 1 1 7 7 7 5 Immunoglobulin domain ig PF00047.25 RUS77552.1 - 1.1e-42 144.1 15.8 6.3e-09 35.9 0.0 7.7 8 1 0 8 8 8 6 Immunoglobulin domain fn3 PF00041.21 RUS77552.1 - 1.2e-30 105.7 14.4 1.1e-08 35.3 0.0 6.3 6 1 0 6 6 5 5 Fibronectin type III domain V-set PF07686.17 RUS77552.1 - 2e-21 76.2 10.3 0.0039 17.3 0.6 9.5 5 3 1 6 6 6 3 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS77552.1 - 5.5e-10 39.5 1.8 0.064 13.7 0.0 6.5 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 RUS77552.1 - 1e-09 38.3 1.1 0.022 14.8 0.0 6.0 6 0 0 6 6 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS77552.1 - 6e-07 28.9 0.0 2.5 7.7 0.0 5.4 6 0 0 6 6 6 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS77552.1 - 4.6e-05 23.9 5.2 0.3 11.7 0.5 4.6 4 0 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 RUS77552.1 - 7.9e-05 22.6 0.4 0.95 9.6 0.1 4.4 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS77552.1 - 0.00029 21.0 0.7 2.1 8.7 0.0 4.9 6 0 0 6 6 4 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 RUS77552.1 - 0.00063 19.9 0.0 0.11 12.7 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Ig_C17orf99 PF17736.1 RUS77552.1 - 0.0099 15.9 0.0 12 6.0 0.0 4.6 4 0 0 4 4 4 0 C17orf99 Ig domain C1-set PF07654.15 RUS77552.1 - 0.019 15.3 7.0 4.1 7.8 0.1 5.1 3 1 2 5 5 5 0 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 RUS77552.1 - 0.28 11.0 2.1 17 5.3 0.1 4.0 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 DUF4594 PF15266.6 RUS77554.1 - 5.9e-15 56.1 30.7 5.9e-15 56.1 30.7 5.8 5 2 2 7 7 7 1 Domain of unknown function (DUF4594) PAM2 PF07145.15 RUS77554.1 - 0.042 13.5 0.1 0.042 13.5 0.1 2.4 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Homeodomain PF00046.29 RUS77556.1 - 1.5e-21 75.9 2.8 2.5e-21 75.3 2.8 1.3 1 0 0 1 1 1 1 Homeodomain Menin PF05053.13 RUS77556.1 - 0.064 11.6 5.2 0.085 11.2 5.2 1.1 1 0 0 1 1 1 0 Menin SatD PF16264.5 RUS77556.1 - 0.091 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 SatD family (SatD) CPSF73-100_C PF11718.8 RUS77556.1 - 2.2 7.8 6.5 0.13 11.8 0.8 1.9 2 1 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Presenilin PF01080.17 RUS77556.1 - 3 6.5 4.6 5.1 5.7 4.6 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 RUS77557.1 - 0.0038 17.3 26.0 0.0044 17.1 26.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 RUS77557.1 - 0.52 8.5 23.3 0.63 8.2 23.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 RUS77557.1 - 0.99 9.4 3.8 1.3 9.1 3.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 RUS77557.1 - 1.8 7.2 10.9 1.9 7.1 10.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.9 RUS77557.1 - 2.2 8.7 9.8 3.7 7.9 9.8 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Zip PF02535.22 RUS77557.1 - 2.9 7.0 5.2 3.5 6.7 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 RUS77557.1 - 3.3 6.4 11.8 4.4 6.0 11.8 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 RUS77557.1 - 3.3 5.7 9.8 4.3 5.3 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 RUS77557.1 - 4 6.8 12.9 5.2 6.5 12.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hydin_ADK PF17213.3 RUS77557.1 - 7.8 6.7 9.6 13 6.0 9.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3585 PF12130.8 RUS77558.1 - 7.2e-12 45.6 0.6 1.2e-11 45.0 0.6 1.2 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain SDA1 PF05285.12 RUS77558.1 - 0.01 15.3 44.8 0.014 14.9 44.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS77558.1 - 0.25 9.5 45.9 0.36 9.0 45.9 1.2 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 RUS77558.1 - 0.38 9.5 3.1 0.49 9.1 3.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 7tm_1 PF00001.21 RUS77559.1 - 0.17 11.2 9.7 1.6 8.0 9.7 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zf-C2H2 PF00096.26 RUS77561.1 - 1e-32 110.7 75.5 0.00013 22.2 2.2 10.8 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77561.1 - 8.4e-24 82.2 88.9 0.0011 19.7 0.6 11.9 12 0 0 12 12 11 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS77561.1 - 1.2e-10 41.1 61.7 0.00096 19.1 0.3 10.5 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS77561.1 - 2.1e-10 40.6 46.6 0.0038 17.5 2.9 9.9 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS77561.1 - 1.5e-06 28.4 48.9 0.0018 18.5 0.5 7.5 6 1 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 RUS77561.1 - 7.6e-05 22.3 31.9 0.25 11.0 0.0 8.9 6 2 4 10 10 10 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 RUS77561.1 - 0.00022 21.5 46.6 0.11 12.9 0.1 9.8 10 0 0 10 10 10 3 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 RUS77561.1 - 0.0051 16.6 14.4 12 5.9 0.0 7.0 6 1 1 7 7 7 1 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 RUS77561.1 - 0.0055 17.0 27.2 1.5 9.2 5.3 5.8 4 1 1 6 6 5 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 RUS77561.1 - 0.0072 16.7 86.8 0.029 14.8 2.0 13.1 14 1 0 14 14 13 4 Zinc-finger double domain TF_Zn_Ribbon PF08271.12 RUS77561.1 - 0.17 11.4 11.4 0.98 9.0 0.3 4.6 3 1 0 3 3 3 0 TFIIB zinc-binding zf-C2HE PF16278.5 RUS77561.1 - 0.2 12.1 37.8 1.7 9.2 0.0 7.6 3 1 4 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 RUS77561.1 - 0.3 11.0 17.1 0.39 10.7 0.4 5.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type SET PF00856.28 RUS77561.1 - 3.9 7.8 4.8 4.6 7.6 0.5 3.1 2 1 0 2 2 2 0 SET domain PhnA_Zn_Ribbon PF08274.12 RUS77561.1 - 6.3 6.9 9.1 20 5.3 0.1 4.4 5 0 0 5 5 5 0 PhnA Zinc-Ribbon HLH PF00010.26 RUS77563.1 - 5.9e-11 42.2 0.3 1e-10 41.4 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomodulin PF03250.14 RUS77565.1 - 3.9e-49 166.3 5.2 3.9e-49 166.3 5.2 2.0 2 0 0 2 2 2 1 Tropomodulin PRA-PH PF01503.17 RUS77565.1 - 0.72 10.3 6.5 19 5.8 0.6 4.0 3 1 1 4 4 4 0 Phosphoribosyl-ATP pyrophosphohydrolase RNase_H2-Ydr279 PF09468.10 RUS77565.1 - 1.2 9.2 5.8 2 8.6 4.9 2.0 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain NicO PF03824.16 RUS77568.1 - 0.3 10.4 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein SID-1_RNA_chan PF13965.6 RUS77568.1 - 0.57 8.5 3.8 0.57 8.5 3.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2052 PF09747.9 RUS77568.1 - 1.8 8.6 31.8 3.4 7.7 31.7 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 RUS77568.1 - 1.9 7.2 18.4 2.3 6.9 18.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 RUS77568.1 - 8 5.0 20.1 8.7 4.9 20.1 1.0 1 0 0 1 1 1 0 Hamartin protein Neur_chan_memb PF02932.16 RUS77568.1 - 9.8 6.2 18.6 15 5.5 18.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2HC_2 PF13913.6 RUS77569.1 - 0.0046 16.8 2.0 0.0056 16.6 0.1 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Ribosomal_L44 PF00935.19 RUS77573.1 - 1.8e-08 34.7 18.0 0.31 11.6 0.3 6.0 3 1 1 6 6 6 5 Ribosomal protein L44 Ret2_MD PF18528.1 RUS77573.1 - 0.00058 20.2 0.1 1.2e+02 3.1 0.0 7.2 8 2 1 9 9 9 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PhoR PF11808.8 RUS77573.1 - 0.066 13.6 9.4 75 3.8 0.0 5.4 3 2 3 6 6 6 0 Phosphate regulon sensor protein PhoR TPR_9 PF13371.6 RUS77574.1 - 0.47 10.6 2.8 0.56 10.4 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat fn3 PF00041.21 RUS77575.1 - 3.8e-69 229.1 9.8 9e-15 54.8 0.1 7.0 6 1 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 RUS77575.1 - 6.4e-49 164.0 0.3 1.2e-15 57.4 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77575.1 - 2.8e-43 146.4 10.8 1.4e-12 48.0 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 RUS77575.1 - 3.9e-35 119.9 1.4 6.2e-11 42.3 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 RUS77575.1 - 1.5e-26 92.5 2.3 3.8e-08 33.6 0.1 5.4 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 RUS77575.1 - 1.2e-15 57.6 9.4 0.00033 20.8 0.1 7.0 5 3 0 5 5 5 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 RUS77575.1 - 5.7e-07 30.0 8.1 0.94 10.1 0.1 7.1 6 3 0 6 6 6 2 Purple acid Phosphatase, N-terminal domain V-set_CD47 PF08204.11 RUS77575.1 - 1.2e-06 28.5 0.0 0.086 12.8 0.0 3.6 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Ig_6 PF18452.1 RUS77575.1 - 0.00015 21.3 0.0 2.2 7.9 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin domain Interfer-bind PF09294.10 RUS77575.1 - 0.00073 19.8 0.0 2.4 8.5 0.0 4.5 5 0 0 5 5 4 1 Interferon-alpha/beta receptor, fibronectin type III Izumo-Ig PF16706.5 RUS77575.1 - 0.002 18.2 0.0 78 3.4 0.0 5.0 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS77575.1 - 0.0055 16.7 0.1 12 6.1 0.1 4.6 3 1 0 4 4 4 1 C17orf99 Ig domain Ig_4 PF16680.5 RUS77575.1 - 0.16 12.2 2.4 38 4.6 0.1 4.6 4 2 0 4 4 3 0 T-cell surface glycoprotein CD3 delta chain Pkinase PF00069.25 RUS77576.1 - 2.6e-33 115.5 0.0 3.3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77576.1 - 3.5e-11 42.9 0.0 4.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS77576.1 - 0.0052 16.1 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Toxin_33 PF08121.11 RUS77576.1 - 1.6 8.6 5.0 0.86 9.5 2.5 1.8 2 0 0 2 2 2 0 Waglerin family zf-C2H2 PF00096.26 RUS77577.1 - 2.4e-44 147.3 164.3 0.0001 22.5 0.8 20.8 20 0 0 20 20 20 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77577.1 - 2.2e-32 108.9 167.7 0.0019 18.9 0.9 21.1 21 0 0 21 21 21 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS77577.1 - 1.4e-12 47.4 141.5 0.00014 22.2 1.2 20.0 21 0 0 21 21 21 12 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS77577.1 - 8.8e-12 44.7 144.6 0.00058 19.8 2.4 19.4 20 1 1 21 21 21 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS77577.1 - 1.8e-09 37.6 86.3 0.005 17.1 0.3 15.2 15 0 0 15 15 15 7 Zinc-finger double-stranded RNA-binding BolA PF01722.18 RUS77577.1 - 0.0016 18.7 3.9 0.49 10.7 0.1 4.7 4 1 1 5 5 5 1 BolA-like protein Spt20 PF12090.8 RUS77577.1 - 0.0066 16.1 8.4 0.014 15.0 8.4 1.5 1 0 0 1 1 1 1 Spt20 family DUF3371 PF11851.8 RUS77577.1 - 0.46 11.6 4.8 2.4 9.3 4.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) SET PF00856.28 RUS77577.1 - 1.9 8.9 4.6 2.8 8.3 0.0 3.4 3 0 0 3 3 3 0 SET domain DUF1664 PF07889.12 RUS77578.1 - 0.003 17.6 3.5 0.003 17.6 3.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) SLAIN PF15301.6 RUS77578.1 - 0.0058 16.0 6.0 0.0068 15.7 6.0 1.1 1 0 0 1 1 1 1 SLAIN motif-containing family Golgin_A5 PF09787.9 RUS77578.1 - 0.02 14.4 25.6 0.21 11.0 25.7 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 RUS77578.1 - 0.16 12.0 0.4 0.45 10.5 0.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAP1_N PF04849.13 RUS77578.1 - 0.18 10.9 21.5 0.047 12.9 7.4 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Prominin PF05478.11 RUS77578.1 - 0.3 9.0 5.2 0.39 8.6 5.2 1.4 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 RUS77578.1 - 0.49 9.7 14.6 0.7 9.2 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 RUS77578.1 - 0.72 9.4 12.3 0.94 9.0 12.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 RUS77578.1 - 1 9.7 16.8 0.17 12.2 2.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein zf-C4H2 PF10146.9 RUS77578.1 - 2 8.7 19.5 15 5.8 4.3 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein DNA_topoisoIV PF00521.20 RUS77578.1 - 2.3 7.0 13.2 3.2 6.6 13.2 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF5446 PF17522.2 RUS77578.1 - 2.8 8.2 12.7 0.91 9.7 0.7 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5446) HIP1_clath_bdg PF16515.5 RUS77578.1 - 4.3 8.0 24.3 0.17 12.5 6.6 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 RUS77578.1 - 4.4 6.3 24.5 0.53 9.3 4.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MDM10 PF12519.8 RUS77578.1 - 7.5 5.3 10.5 9.4 5.0 10.5 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 OmpH PF03938.14 RUS77578.1 - 8.1 6.8 27.6 0.38 11.1 8.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3337 PF11816.8 RUS77579.1 - 3.3e-44 150.8 0.0 5.4e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 RUS77579.1 - 6.5e-30 102.7 17.6 2.3e-05 25.1 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77579.1 - 5.4e-07 29.8 2.3 0.28 11.5 0.1 4.4 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RUS77579.1 - 0.0012 17.7 0.3 0.77 8.4 0.1 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 RUS77579.1 - 0.0015 17.3 5.5 0.51 8.9 0.8 3.8 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS77579.1 - 0.018 14.0 0.2 1.1 8.2 0.0 2.4 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 RUS77579.1 - 0.053 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40_like PF17005.5 RUS77579.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain Ank_2 PF12796.7 RUS77580.1 - 6.2e-29 100.4 0.0 1.9e-15 57.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RUS77580.1 - 4.3e-19 68.0 1.9 1.1e-06 28.8 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 RUS77580.1 - 5e-19 68.4 0.1 5.2e-09 36.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS77580.1 - 2.1e-17 63.0 0.0 7e-06 26.2 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS77580.1 - 3.4e-16 57.7 0.0 0.0031 17.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Acetyltransf_1 PF00583.25 RUS77583.1 - 0.0034 17.6 0.1 0.012 15.9 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family PHB_acc_N PF07879.11 RUS77583.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain WD40 PF00400.32 RUS77584.1 - 2.4e-13 50.3 0.3 3.9e-10 40.1 0.0 3.0 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77584.1 - 0.0031 17.8 0.0 0.032 14.5 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS77584.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PsiB PF06290.11 RUS77586.1 - 0.56 9.7 2.9 98 2.4 0.0 4.2 1 1 3 5 5 5 0 Plasmid SOS inhibition protein (PsiB) NAD_binding_5 PF07994.12 RUS77588.1 - 0.18 11.2 0.5 4.6 6.5 0.0 2.6 2 1 1 3 3 3 0 Myo-inositol-1-phosphate synthase GTP_cyclohydroI PF01227.22 RUS77588.1 - 6.9 6.0 9.2 11 5.4 1.9 3.0 1 1 1 3 3 3 0 GTP cyclohydrolase I ABC2_membrane PF01061.24 RUS77589.1 - 1.6e-45 155.1 27.9 2.4e-45 154.6 27.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RUS77589.1 - 6.5e-30 104.4 0.0 1e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS77589.1 - 1.4e-07 31.2 0.0 2.9e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RUS77589.1 - 1.5e-06 28.3 0.0 0.011 15.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RUS77589.1 - 3.3e-05 23.9 0.1 5.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 RUS77589.1 - 0.00033 19.9 11.5 0.00033 19.9 11.5 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 RUS77589.1 - 0.016 15.3 0.2 0.035 14.2 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS77589.1 - 0.019 14.7 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS77589.1 - 0.03 14.7 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 RUS77589.1 - 0.042 14.1 0.0 0.79 10.0 0.0 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RUS77589.1 - 0.043 14.3 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1440 PF07274.12 RUS77589.1 - 0.25 11.7 3.6 3.6 7.9 3.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) Claudin_2 PF13903.6 RUS77590.1 - 3.9e-13 49.6 12.1 6.8e-13 48.8 12.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS77590.1 - 1.4e-06 28.3 13.4 2.3e-06 27.6 13.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RUS77590.1 - 1.9e-06 27.9 8.1 3.8e-06 26.9 8.1 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Clc-like PF07062.12 RUS77590.1 - 0.0076 15.7 16.6 2.3 7.6 16.6 2.3 1 1 0 1 1 1 1 Clc-like DUF4064 PF13273.6 RUS77590.1 - 0.031 14.6 7.8 0.059 13.6 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DuoxA PF10204.9 RUS77590.1 - 0.2 10.7 9.0 0.018 14.1 2.5 2.0 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF4383 PF14325.6 RUS77590.1 - 0.43 10.9 7.8 0.068 13.5 2.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) Herpes_LAMP2 PF06126.11 RUS77590.1 - 0.88 8.1 11.8 0.0083 14.8 3.8 1.5 2 0 0 2 2 2 0 Herpesvirus Latent membrane protein 2 MASE5 PF17178.4 RUS77590.1 - 1.8 8.4 6.8 0.35 10.7 1.6 2.0 2 0 0 2 2 2 0 Membrane-associated sensor YtpI PF14007.6 RUS77590.1 - 2.9 8.1 5.9 0.34 11.1 0.6 2.0 2 0 0 2 2 2 0 YtpI-like protein 3Beta_HSD PF01073.19 RUS77592.1 - 5.6e-07 28.8 0.0 7.2e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS77592.1 - 1.9e-06 27.6 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RUS77592.1 - 3.7e-06 26.3 0.0 5.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sec23_trunk PF04811.15 RUS77592.1 - 0.047 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain MFS_1 PF07690.16 RUS77593.1 - 1.5e-23 83.4 6.0 3.8e-23 82.0 3.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_31 PF13847.6 RUS77594.1 - 5.9e-30 104.1 0.0 9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS77594.1 - 1.6e-16 60.7 0.0 2.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS77594.1 - 4e-16 59.4 0.0 7.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS77594.1 - 8.1e-14 51.5 0.1 1.5e-13 50.6 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS77594.1 - 5.3e-11 42.6 0.0 8.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS77594.1 - 8.7e-09 36.0 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RUS77594.1 - 5.6e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 RUS77594.1 - 0.0027 17.1 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RUS77594.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 RUS77594.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 RUS77594.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 RUS77594.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 RUS77594.1 - 0.048 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 RUS77594.1 - 0.11 12.1 1.0 2.6 7.6 1.0 2.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW hDGE_amylase PF14701.6 RUS77596.1 - 1.8e-140 468.9 0.0 2.5e-140 468.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 RUS77596.1 - 1.1e-117 393.2 0.0 1.5e-117 392.8 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 RUS77596.1 - 3.5e-79 266.0 0.0 5.8e-79 265.3 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 RUS77596.1 - 6.4e-20 71.1 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 RUS77596.1 - 0.0081 15.8 0.0 0.082 12.5 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain cobW PF02492.19 RUS77597.1 - 1.9e-50 170.9 0.6 2.8e-50 170.3 0.6 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 RUS77597.1 - 7.6e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 RUS77597.1 - 0.00018 21.5 0.4 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 RUS77597.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 RUS77597.1 - 0.0043 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MeaB PF03308.16 RUS77597.1 - 0.0068 15.4 0.8 1.1 8.1 0.1 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RUS77597.1 - 0.0091 16.5 0.8 0.033 14.7 0.1 2.1 2 0 0 2 2 2 1 ABC transporter ATP_bind_1 PF03029.17 RUS77597.1 - 0.014 15.2 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 RUS77597.1 - 0.014 15.7 0.4 0.094 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 RUS77597.1 - 0.016 14.9 0.1 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RUS77597.1 - 0.017 15.2 0.1 0.13 12.4 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RUS77597.1 - 0.022 15.3 0.7 0.022 15.3 0.7 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RUS77597.1 - 0.052 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS77597.1 - 0.07 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PCB_OB PF17092.5 RUS77597.1 - 0.12 13.1 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Viral_helicase1 PF01443.18 RUS77597.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_M2 PF04887.12 RUS77598.1 - 0.13 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus M2 protein DctQ PF04290.12 RUS77599.1 - 0.037 14.0 0.3 0.037 14.0 0.3 3.1 4 0 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pro_isomerase PF00160.21 RUS77600.1 - 4.2e-49 166.8 0.1 9e-49 165.8 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 RUS77600.1 - 1.4e-12 47.9 0.0 0.0052 17.6 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS77600.1 - 4.5e-07 30.1 0.0 0.002 18.4 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS77600.1 - 0.00075 18.6 0.1 5.2 5.9 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2 PF00096.26 RUS77601.1 - 8.8e-10 38.5 30.3 0.00043 20.6 2.4 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS77601.1 - 2.1e-08 34.2 24.5 1.2e-05 25.4 1.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS77601.1 - 0.0015 19.2 36.8 0.002 18.8 1.6 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 RUS77601.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CABIT PF12736.7 RUS77602.1 - 2.7e-07 30.2 0.0 4.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, Thioredoxin_8 PF13905.6 RUS77603.1 - 2.9e-27 94.8 0.0 3.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 RUS77603.1 - 1e-11 44.7 0.0 8.5e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RUS77603.1 - 2.8e-07 31.0 0.0 4.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 RUS77603.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RUS77603.1 - 3e-05 23.9 0.0 5.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 RUS77603.1 - 0.0091 15.8 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 RUS77603.1 - 0.0094 16.2 0.0 0.33 11.2 0.0 2.5 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 RUS77603.1 - 0.08 12.7 0.0 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin WD40 PF00400.32 RUS77604.1 - 7.7e-05 23.4 1.6 0.13 13.2 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat IFT46_B_C PF12317.8 RUS77605.1 - 0.11 12.2 2.3 0.21 11.3 2.3 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Cadherin PF00028.17 RUS77607.1 - 8.3e-104 340.3 3.6 6.2e-21 74.6 0.0 7.8 8 0 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 RUS77607.1 - 1.4e-14 53.7 0.0 5.3e-06 26.2 0.0 7.0 7 0 0 7 7 7 3 Cadherin-like Cadherin_3 PF16184.5 RUS77607.1 - 1.1e-08 35.0 7.8 0.14 12.2 0.0 6.0 6 1 0 6 6 6 2 Cadherin-like DUF5408 PF17402.2 RUS77607.1 - 0.035 14.0 0.5 0.075 12.9 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Shisa PF13908.6 RUS77607.1 - 0.039 14.2 0.2 0.089 13.0 0.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 RUS77607.1 - 0.042 13.7 0.2 0.042 13.7 0.2 2.1 2 0 0 2 2 2 0 TMEM154 protein family OSTbeta PF15048.6 RUS77607.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein EphA2_TM PF14575.6 RUS77607.1 - 0.11 13.3 0.1 0.28 12.1 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5527 PF17665.1 RUS77607.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CAP_GLY PF01302.25 RUS77609.1 - 2.7e-19 69.0 0.0 5.1e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Pox_A_type_inc PF04508.12 RUS77609.1 - 0.89 9.5 8.7 0.14 12.0 3.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FAM76 PF16046.5 RUS77610.1 - 1.4e-92 310.2 53.9 1.2e-67 228.4 21.3 2.0 2 0 0 2 2 2 2 FAM76 protein DUF773 PF05600.12 RUS77610.1 - 0.00017 20.5 5.6 0.00028 19.8 5.6 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Spc7 PF08317.11 RUS77610.1 - 0.0059 15.5 7.4 0.0092 14.9 7.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 RUS77610.1 - 0.0073 16.5 9.4 0.0073 16.5 9.4 2.1 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 CC2-LZ PF16516.5 RUS77610.1 - 0.058 13.8 7.8 0.055 13.8 5.6 2.0 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KASH_CCD PF14662.6 RUS77610.1 - 0.13 12.0 12.6 0.11 12.3 8.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH MbeD_MobD PF04899.12 RUS77610.1 - 0.14 12.3 2.4 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like MPS2 PF17060.5 RUS77610.1 - 0.21 10.8 9.7 0.38 10.0 9.7 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 OmpH PF03938.14 RUS77610.1 - 0.31 11.4 8.2 0.66 10.3 8.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 RUS77610.1 - 0.69 9.9 8.3 1 9.4 8.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.13 RUS77610.1 - 1.3 9.9 5.8 12 6.7 5.8 2.4 1 1 0 1 1 1 0 Flagellar protein FliT Prefoldin_2 PF01920.20 RUS77610.1 - 1.6 8.7 13.2 2.6 8.0 6.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 RUS77610.1 - 2.9 8.0 6.4 4.9 7.2 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 RUS77610.1 - 3.8 7.6 15.1 2.6 8.1 4.8 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 RUS77610.1 - 5.3 7.7 8.6 60 4.4 4.6 2.8 1 1 1 2 2 2 0 SlyX Csm1_N PF18504.1 RUS77610.1 - 6.8 7.1 12.7 3.8 7.9 4.7 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Vg_Tdu PF07545.14 RUS77611.1 - 0.033 14.0 0.0 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family Popeye PF04831.13 RUS77612.1 - 1e-47 161.8 0.8 1.2e-47 161.5 0.8 1.1 1 0 0 1 1 1 1 Popeye protein conserved region HNH_3 PF13392.6 RUS77613.1 - 0.038 13.8 3.0 12 5.8 0.1 4.5 5 0 0 5 5 5 0 HNH endonuclease Prion PF00377.18 RUS77613.1 - 0.17 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain DUF1147 PF06615.11 RUS77614.1 - 0.0044 17.0 3.4 23 5.1 0.0 4.6 4 0 0 4 4 4 4 Protein of unknown function (DUF1147) MAM PF00629.23 RUS77615.1 - 3.2e-13 49.9 0.0 4.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Popeye PF04831.13 RUS77616.1 - 9e-36 123.1 1.2 1.1e-35 122.8 1.2 1.1 1 0 0 1 1 1 1 Popeye protein conserved region Zf_RING PF16744.5 RUS77616.1 - 0.047 13.8 1.0 1.4 9.1 0.4 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger DUF4629 PF15442.6 RUS77616.1 - 0.81 9.9 5.0 1.3 9.3 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Pap_E4 PF02711.14 RUS77616.1 - 3.4 8.7 8.9 20 6.2 2.2 2.6 3 0 0 3 3 3 0 E4 protein DUF3432 PF11914.8 RUS77617.1 - 0.0062 16.8 2.8 0.3 11.4 1.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) MHC_II_beta PF00969.19 RUS77617.1 - 0.0072 16.4 13.0 10 6.3 0.3 5.5 1 1 4 5 5 5 4 Class II histocompatibility antigen, beta domain DUF1601 PF07671.11 RUS77617.1 - 0.22 11.4 48.4 20 5.1 0.3 11.8 2 2 10 13 13 13 0 Protein of unknown function (DUF1601) PliI PF16743.5 RUS77617.1 - 3 7.6 12.9 75 3.1 0.1 5.1 1 1 2 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme Catalase PF00199.19 RUS77618.1 - 1.7e-199 662.7 0.0 2e-199 662.5 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RUS77618.1 - 1.1e-19 70.4 1.1 2.8e-19 69.1 0.1 2.3 3 0 0 3 3 3 1 Catalase-related immune-responsive Ank_2 PF12796.7 RUS77619.1 - 1.9e-102 336.0 23.5 2.6e-16 60.0 1.0 8.9 2 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS77619.1 - 2.1e-86 283.3 27.6 4e-11 43.2 0.0 13.0 7 5 7 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 RUS77619.1 - 1e-79 259.7 27.4 1.1e-06 28.8 0.3 15.6 14 1 1 15 15 15 14 Ankyrin repeat Ank_3 PF13606.6 RUS77619.1 - 7.9e-79 250.1 21.9 2.7e-05 24.2 0.1 17.3 18 0 0 18 18 18 14 Ankyrin repeat Ank_5 PF13857.6 RUS77619.1 - 2.8e-74 244.2 31.1 1.3e-09 38.1 0.5 13.4 5 5 8 13 13 13 12 Ankyrin repeats (many copies) Ion_trans PF00520.31 RUS77619.1 - 7.3e-19 68.0 25.2 1.1e-18 67.4 25.2 1.2 1 0 0 1 1 1 1 Ion transport protein CENP-H PF05837.12 RUS77619.1 - 0.023 15.1 1.0 0.06 13.8 1.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Snapin_Pallidin PF14712.6 RUS77619.1 - 0.19 12.2 2.4 0.58 10.6 2.4 1.8 1 0 0 1 1 1 0 Snapin/Pallidin NPV_P10 PF05531.12 RUS77619.1 - 0.29 11.6 2.0 1.2 9.6 2.0 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Hist_deacetyl PF00850.19 RUS77621.1 - 1.2e-78 264.7 0.0 1.9e-78 264.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain VIT PF08487.10 RUS77622.1 - 7.6e-40 135.6 0.1 2.2e-39 134.1 0.1 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PARP PF00644.20 RUS77622.1 - 8e-32 110.4 0.1 3.8e-31 108.2 0.1 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ubiquitin PF00240.23 RUS77622.1 - 2e-18 65.9 0.0 4.9e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family VWA_3 PF13768.6 RUS77622.1 - 2.9e-15 56.6 0.0 6.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 RUS77622.1 - 8.7e-13 48.0 0.0 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain BRCT_2 PF16589.5 RUS77622.1 - 4.2e-09 36.7 0.1 1.8e-08 34.7 0.0 2.1 2 0 0 2 2 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RUS77622.1 - 1e-08 35.4 1.3 2.2e-08 34.4 0.1 2.3 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain Rad60-SLD PF11976.8 RUS77622.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PARP_reg PF02877.14 RUS77622.1 - 0.00015 21.9 0.6 0.00038 20.6 0.6 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Nucleoporin_FG PF13634.6 RUS77622.1 - 0.0002 22.1 13.2 0.0002 22.1 13.2 5.5 2 1 3 5 5 2 1 Nucleoporin FG repeat region VWA_2 PF13519.6 RUS77622.1 - 0.00039 21.1 0.0 0.0025 18.4 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RUS77622.1 - 0.00078 19.7 0.0 0.0036 17.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD_2 PF13881.6 RUS77622.1 - 0.0011 19.0 0.0 0.0043 17.2 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PTCB-BRCT PF12738.7 RUS77622.1 - 0.0017 18.2 0.4 0.0082 16.1 0.0 2.3 3 0 0 3 3 3 1 twin BRCT domain EcoR124_C PF12008.8 RUS77622.1 - 0.06 13.0 0.5 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal YkyA PF10368.9 RUS77622.1 - 2.3 7.9 7.8 0.24 11.1 1.6 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CRAL_TRIO_2 PF13716.6 RUS77623.1 - 1.4e-38 132.2 3.5 1.8e-38 131.8 1.9 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 RUS77623.1 - 8.4e-36 123.1 0.0 1.6e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 RUS77623.1 - 2.5e-06 27.3 1.6 6.9e-06 25.9 1.6 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain Nod1 PF17114.5 RUS77623.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF3575 PF12099.8 RUS77625.1 - 0.18 11.1 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) DUF4816 PF16086.5 RUS77626.1 - 0.033 14.1 6.0 32 4.6 0.1 6.4 8 0 0 8 8 8 0 Domain of unknown function (DUF4816) RCC1_2 PF13540.6 RUS77627.1 - 0.067 13.0 7.5 0.36 10.7 0.1 3.7 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat GON PF08685.11 RUS77628.1 - 2.7e-42 144.9 0.3 3e-42 144.8 0.3 1.0 1 0 0 1 1 1 1 GON domain TSP_1 PF00090.19 RUS77630.1 - 1.5e-13 50.7 43.2 1.5e-05 25.1 10.1 4.1 4 0 0 4 4 4 3 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 RUS77631.1 - 2.2e-21 76.0 0.0 2.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 RUS77633.1 - 3e-18 66.5 0.0 3.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS77633.1 - 5.6e-16 59.3 0.0 7.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS77633.1 - 7e-10 39.5 0.0 9.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS77633.1 - 2.3e-07 30.9 0.0 4.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS77633.1 - 0.00037 20.2 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M78 PF06114.13 RUS77633.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M10 PF00413.24 RUS77633.1 - 0.074 12.9 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 RUS77633.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Metallopep PF12044.8 RUS77633.1 - 0.2 10.3 0.1 0.26 9.8 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Drf_FH1 PF06346.12 RUS77634.1 - 0.0057 16.4 1.7 0.0071 16.1 1.7 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 BetaGal_dom3 PF13363.6 RUS77634.1 - 0.0082 15.7 0.6 17 5.1 0.0 3.4 1 1 2 3 3 3 2 Beta-galactosidase, domain 3 Tryp_inh PF17983.1 RUS77634.1 - 6.5 6.9 21.6 19 5.4 0.2 5.4 4 2 2 6 6 6 0 Trypsin inhibitors 1,2 and 3 Nitrate_red_gam PF02665.14 RUS77634.1 - 7.3 6.1 9.0 9.7 5.7 1.3 2.1 1 1 1 2 2 2 0 Nitrate reductase gamma subunit RasGEF PF00617.19 RUS77637.1 - 6.2e-58 195.9 0.7 1.9e-57 194.3 0.7 1.9 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.20 RUS77637.1 - 3.4e-32 112.1 3.1 3.4e-32 112.1 3.1 3.0 4 0 0 4 4 4 1 RhoGEF domain PH PF00169.29 RUS77637.1 - 3.5e-25 88.5 0.0 8.1e-19 68.1 0.0 2.8 2 0 0 2 2 2 2 PH domain RasGEF_N PF00618.20 RUS77637.1 - 2.8e-23 82.2 0.0 1.9e-15 57.0 0.0 3.2 2 0 0 2 2 2 2 RasGEF N-terminal motif PH_11 PF15413.6 RUS77637.1 - 0.00018 21.9 1.1 0.0018 18.7 1.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 RUS77637.1 - 0.0011 18.8 0.2 0.47 10.3 0.0 3.2 3 0 0 3 3 3 1 PH domain PH_13 PF16652.5 RUS77637.1 - 0.0013 18.6 0.6 0.035 13.9 0.2 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain IQ PF00612.27 RUS77637.1 - 0.002 17.8 1.9 0.0045 16.7 1.9 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif TGT_C2 PF14810.6 RUS77637.1 - 0.0058 16.7 0.2 0.56 10.4 0.0 2.6 2 0 0 2 2 2 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PH_8 PF15409.6 RUS77637.1 - 0.018 15.3 3.3 0.18 12.1 0.9 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain SHE3 PF17078.5 RUS77637.1 - 0.068 12.9 9.0 0.5 10.0 5.6 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Med28 PF11594.8 RUS77637.1 - 0.8 9.8 5.3 16 5.6 3.6 3.3 2 1 0 2 2 2 0 Mediator complex subunit 28 CortBP2 PF09727.9 RUS77637.1 - 1.3 8.8 11.3 0.34 10.8 6.9 2.2 2 0 0 2 2 2 0 Cortactin-binding protein-2 Sec1 PF00995.23 RUS77638.1 - 1.8e-133 446.8 0.9 2.2e-133 446.6 0.9 1.0 1 0 0 1 1 1 1 Sec1 family V-ATPase_H_C PF11698.8 RUS77638.1 - 0.12 12.5 0.1 0.74 9.9 0.1 2.4 3 0 0 3 3 3 0 V-ATPase subunit H p450 PF00067.22 RUS77639.1 - 4.4e-63 213.6 0.2 1.4e-61 208.6 0.2 2.0 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 RUS77640.1 - 9.6e-112 373.1 20.4 2.7e-65 220.7 2.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS77640.1 - 2.2e-73 245.2 0.1 1.3e-36 126.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS77640.1 - 1.2e-14 54.3 0.1 2.3e-05 24.0 0.1 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS77640.1 - 2.1e-09 37.8 0.2 0.00052 20.3 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS77640.1 - 6.1e-09 36.5 1.7 0.0034 17.8 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RUS77640.1 - 1.8e-08 33.7 1.2 0.00011 21.2 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 RUS77640.1 - 2.9e-06 27.3 0.1 0.0091 15.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 RUS77640.1 - 1.4e-05 25.2 3.7 0.12 12.6 0.2 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 RUS77640.1 - 1.6e-05 24.9 0.3 0.17 11.8 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_5 PF07728.14 RUS77640.1 - 2e-05 24.6 0.1 0.28 11.2 0.0 3.8 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RUS77640.1 - 2.5e-05 24.1 0.3 0.92 9.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RUS77640.1 - 3.9e-05 23.3 0.2 0.21 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 RUS77640.1 - 4.4e-05 23.9 1.5 0.21 12.0 0.0 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 RUS77640.1 - 6.2e-05 22.4 0.0 0.0098 15.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 RUS77640.1 - 7.2e-05 22.1 0.0 0.056 12.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 RUS77640.1 - 9.1e-05 22.0 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 RUS77640.1 - 0.00086 19.1 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 RUS77640.1 - 0.0017 17.9 0.2 0.23 11.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS77640.1 - 0.0024 18.1 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 RUS77640.1 - 0.0036 17.0 0.1 0.65 9.6 0.0 2.9 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 RUS77640.1 - 0.0041 16.3 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 RUS77640.1 - 0.0044 17.4 0.0 3 8.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 RUS77640.1 - 0.0051 16.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS77640.1 - 0.0053 16.7 0.2 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 RUS77640.1 - 0.013 15.6 0.1 4.7 7.2 0.0 3.1 4 0 0 4 4 3 0 Helicase HerA, central domain PRK PF00485.18 RUS77640.1 - 0.019 14.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 RUS77640.1 - 0.029 13.6 0.1 8.4 5.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 RUS77640.1 - 0.042 13.8 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase tRNA_lig_kinase PF08303.11 RUS77640.1 - 0.065 13.3 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_21 PF13304.6 RUS77640.1 - 0.075 12.8 0.0 4 7.2 0.0 3.3 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 RUS77640.1 - 0.088 12.5 0.0 7.8 6.2 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2057 PF09829.9 RUS77640.1 - 0.12 12.6 0.9 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF2594 PF10769.9 RUS77640.1 - 0.17 12.0 0.3 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) AAA_33 PF13671.6 RUS77640.1 - 0.18 12.0 0.1 13 6.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF3265 PF11665.8 RUS77640.1 - 0.22 11.7 2.3 42 4.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3265) ABC_membrane PF00664.23 RUS77641.1 - 6.9e-71 239.1 4.1 8.5e-66 222.4 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS77641.1 - 4.3e-49 166.5 0.0 3.6e-36 124.7 0.0 2.7 1 1 1 2 2 2 2 ABC transporter AAA_16 PF13191.6 RUS77641.1 - 1.5e-09 38.5 1.1 0.0021 18.4 0.3 3.0 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RUS77641.1 - 6.1e-09 35.6 0.3 2.2e-05 24.0 0.0 3.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RUS77641.1 - 1.5e-08 34.7 0.9 0.0063 16.4 0.1 2.6 1 1 1 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS77641.1 - 1.7e-07 31.6 0.5 0.035 14.4 0.1 3.1 1 1 1 2 2 2 2 AAA domain G-alpha PF00503.20 RUS77641.1 - 1.4e-06 27.7 0.0 0.041 13.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Rad17 PF03215.15 RUS77641.1 - 1.6e-06 28.2 0.1 0.05 13.5 0.0 2.9 2 1 1 3 3 2 2 Rad17 P-loop domain AAA_7 PF12775.7 RUS77641.1 - 2.1e-06 27.4 0.1 0.036 13.6 0.0 2.4 1 1 1 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 RUS77641.1 - 2.7e-06 27.0 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 RUS77641.1 - 3.5e-06 27.0 0.1 0.2 11.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 RUS77641.1 - 3.9e-06 26.8 0.0 0.058 13.1 0.0 3.0 1 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 RUS77641.1 - 6.2e-06 25.9 0.1 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RUS77641.1 - 1.1e-05 24.8 0.3 0.065 12.5 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin ATP-synt_ab PF00006.25 RUS77641.1 - 7.7e-05 22.4 1.0 0.21 11.2 0.1 2.6 1 1 1 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 RUS77641.1 - 0.00024 21.5 0.2 0.4 11.1 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RUS77641.1 - 0.00027 20.9 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_21 PF13304.6 RUS77641.1 - 0.0003 20.7 0.0 1.9 8.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 RUS77641.1 - 0.0003 20.6 0.0 0.21 11.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RUS77641.1 - 0.00034 21.2 0.0 1.9 9.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 RUS77641.1 - 0.00039 20.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 RUS77641.1 - 0.00055 20.3 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 RUS77641.1 - 0.00059 19.1 0.1 0.66 9.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 RUS77641.1 - 0.00062 19.5 0.3 1.2 8.8 0.1 2.8 1 1 1 2 2 2 2 AAA domain DUF87 PF01935.17 RUS77641.1 - 0.00076 19.6 1.0 3 7.9 0.0 3.2 2 1 1 3 3 3 1 Helicase HerA, central domain tRNA_lig_kinase PF08303.11 RUS77641.1 - 0.0026 17.9 0.1 1.3 9.1 0.1 2.8 2 0 0 2 2 2 1 tRNA ligase kinase domain Sigma54_activat PF00158.26 RUS77641.1 - 0.0042 16.8 0.1 4.1 7.1 0.0 2.8 1 1 1 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 RUS77641.1 - 0.0043 17.2 0.1 4.1 7.5 0.0 2.6 1 1 1 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 RUS77641.1 - 0.0046 17.0 0.0 5.3 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 RUS77641.1 - 0.0054 17.0 0.2 0.085 13.1 0.2 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 RUS77641.1 - 0.0056 16.8 0.1 8.3 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 RUS77641.1 - 0.0073 16.2 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase ATPase PF06745.13 RUS77641.1 - 0.009 15.4 0.5 4.6 6.5 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 RUS77641.1 - 0.012 15.9 0.1 9.6 6.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RUS77641.1 - 0.013 15.2 0.8 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RUS77641.1 - 0.015 14.8 0.0 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_ATPase PF09818.9 RUS77641.1 - 0.02 13.7 1.8 0.038 12.8 0.1 2.2 2 1 1 3 3 3 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 RUS77641.1 - 0.024 15.2 0.3 15 6.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 RUS77641.1 - 0.028 13.6 2.4 3.6 6.7 0.2 2.5 1 1 1 2 2 2 0 NB-ARC domain DLIC PF05783.11 RUS77641.1 - 0.041 12.7 0.1 4 6.1 0.0 2.2 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) Septin PF00735.18 RUS77641.1 - 0.044 13.1 0.0 8.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_17 PF13207.6 RUS77641.1 - 0.046 14.2 0.2 23 5.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 RUS77641.1 - 0.046 13.1 0.0 18 4.6 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein Mg_chelatase PF01078.21 RUS77641.1 - 0.058 12.8 0.1 9.3 5.6 0.0 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI CoaE PF01121.20 RUS77641.1 - 0.062 13.0 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Roc PF08477.13 RUS77641.1 - 0.071 13.3 0.1 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 RUS77641.1 - 0.08 12.7 0.1 20 4.8 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 RUS77641.1 - 0.082 12.9 1.1 13 5.8 0.1 2.4 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 RUS77641.1 - 0.12 12.3 0.1 23 4.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RhoGAP PF00620.27 RUS77643.1 - 4.2e-47 159.8 0.1 1.6e-46 157.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 RUS77643.1 - 0.00026 21.2 0.3 0.0013 19.0 0.3 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2046 PF09755.9 RUS77644.1 - 0.027 13.7 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF4482 PF14818.6 RUS77644.1 - 0.066 14.1 0.5 0.066 14.1 0.5 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) EF-hand_3 PF09069.11 RUS77645.1 - 5.3e-18 65.2 0.0 1.5e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand EF-hand_2 PF09068.11 RUS77645.1 - 7.9e-16 58.3 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 EF hand WW PF00397.26 RUS77645.1 - 0.0017 18.4 0.3 0.0038 17.3 0.3 1.6 1 0 0 1 1 1 1 WW domain Mitoc_L55 PF09776.9 RUS77647.1 - 9.2e-34 115.6 0.1 1e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 PQ-loop PF04193.14 RUS77648.1 - 2.8e-34 116.7 20.4 5.6e-18 64.5 0.9 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF423 PF04241.15 RUS77648.1 - 1.8 8.8 4.2 4.4 7.6 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF423) MFS_1 PF07690.16 RUS77649.1 - 5e-50 170.4 33.7 4.2e-49 167.4 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS77649.1 - 4e-06 26.0 30.0 5e-06 25.6 13.1 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter Transglut_core PF01841.19 RUS77650.1 - 4.7e-06 27.0 0.7 2.1e-05 24.9 0.7 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily MnmE_helical PF12631.7 RUS77650.1 - 0.0068 16.6 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 MnmE helical domain Cadherin_5 PF17892.1 RUS77650.1 - 0.047 13.7 0.3 4.3 7.4 0.1 2.7 1 1 1 2 2 2 0 Cadherin-like domain Big_3_4 PF13754.6 RUS77650.1 - 0.048 13.4 0.1 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function 7tm_1 PF00001.21 RUS77651.1 - 1.6e-31 109.6 36.3 2.3e-29 102.5 23.2 3.3 3 1 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) C_tripleX PF02363.19 RUS77652.1 - 0.12 12.7 25.0 1.8e+04 -11.0 25.0 4.2 1 1 0 1 1 1 0 Cysteine rich repeat Peptidase_C21 PF05381.12 RUS77652.1 - 2.6 8.4 10.6 4.1 7.8 1.7 2.8 1 1 0 2 2 2 0 Tymovirus endopeptidase RXT2_N PF08595.11 RUS77653.1 - 0.061 13.3 16.4 0.45 10.5 8.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIA PF03153.13 RUS77653.1 - 0.17 11.8 20.9 0.26 11.2 20.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.10 RUS77653.1 - 0.45 10.8 12.1 3 8.1 2.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 RUS77653.1 - 0.54 8.6 21.9 0.42 9.0 4.0 2.1 2 0 0 2 2 2 0 Mpp10 protein PPP4R2 PF09184.11 RUS77653.1 - 0.78 9.3 21.2 0.84 9.2 10.5 2.1 2 0 0 2 2 2 0 PPP4R2 RNA_polI_A34 PF08208.11 RUS77653.1 - 1.9 8.6 16.1 0.22 11.6 5.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RPA43_OB PF17875.1 RUS77653.1 - 2.8 8.6 10.7 1.8 9.2 2.9 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I TRM13 PF05206.14 RUS77653.1 - 6.4 6.2 6.3 5.4 6.5 2.3 2.0 2 0 0 2 2 2 0 Methyltransferase TRM13 TraB PF01963.17 RUS77654.1 - 9.2e-11 42.1 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 TraB family Glyco_tran_WecB PF03808.13 RUS77654.1 - 0.063 13.2 0.1 4 7.3 0.0 2.1 1 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family SDA1 PF05285.12 RUS77654.1 - 0.28 10.5 6.6 0.27 10.6 6.6 1.1 1 0 0 1 1 1 0 SDA1 wnt PF00110.19 RUS77655.1 - 3.2e-120 401.4 20.1 3.7e-120 401.2 20.1 1.0 1 0 0 1 1 1 1 wnt family Linker_histone PF00538.19 RUS77656.1 - 4.6e-10 39.7 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family EGF PF00008.27 RUS77657.1 - 7.2e-16 58.2 36.9 2.9e-06 27.4 5.5 3.9 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 RUS77657.1 - 0.00083 19.7 41.6 0.03 14.7 8.4 4.1 3 0 0 3 3 3 3 EGF-like domain TMEM51 PF15345.6 RUS77657.1 - 0.0047 16.8 9.2 0.21 11.4 0.0 2.6 2 0 0 2 2 2 1 Transmembrane protein 51 PBP1_TM PF14812.6 RUS77657.1 - 0.031 14.6 1.0 0.031 14.6 1.0 6.9 5 1 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3377 PF11857.8 RUS77657.1 - 0.1 12.5 2.6 0.37 10.7 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4407 PF14362.6 RUS77657.1 - 0.24 10.7 3.1 0.58 9.4 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TERB2 PF15101.6 RUS77657.1 - 2.4 8.2 8.8 6.5 6.7 8.8 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 RUS77657.1 - 9 5.8 32.6 22 4.5 32.6 1.6 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 RUS77658.1 - 5e-12 46.2 9.8 0.00023 21.9 0.2 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 RUS77658.1 - 0.00023 19.9 1.1 0.00073 18.3 0.4 2.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 zf-CCHC PF00098.23 RUS77664.1 - 5.8e-05 23.0 1.3 0.0001 22.2 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS77664.1 - 0.0037 16.9 0.5 0.0037 16.9 0.5 1.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger LMBR1 PF04791.16 RUS77664.1 - 0.011 14.7 1.5 0.012 14.6 1.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PIEZO PF15917.5 RUS77664.1 - 0.017 14.6 7.3 0.026 14.0 7.3 1.2 1 0 0 1 1 1 0 Piezo YabA PF06156.13 RUS77664.1 - 0.031 14.9 4.0 0.052 14.2 4.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF489 PF04356.12 RUS77664.1 - 0.032 14.2 0.2 0.041 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF1002 PF06207.11 RUS77664.1 - 0.063 12.8 2.0 0.09 12.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) zf-CCHC_2 PF13696.6 RUS77664.1 - 0.068 13.0 0.4 0.099 12.5 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle GTPase_binding PF09027.10 RUS77664.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 GTPase binding COG2 PF06148.11 RUS77664.1 - 0.086 12.9 4.7 0.17 12.0 4.7 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 RUS77664.1 - 0.14 10.1 1.5 0.14 10.0 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4194 PF13835.6 RUS77664.1 - 0.24 11.1 7.7 0.061 13.1 3.6 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4194) UPF0242 PF06785.11 RUS77664.1 - 0.7 10.0 7.6 0.86 9.7 7.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 RUS77664.1 - 1.3 8.2 3.7 1.7 7.8 3.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein SAM_1 PF00536.30 RUS77665.1 - 0.1 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MFS_2 PF13347.6 RUS77666.1 - 1.2e-96 324.0 24.2 1.3e-96 323.8 24.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 RUS77666.1 - 1.6e-14 53.6 12.9 1.6e-14 53.6 12.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PQ-loop PF04193.14 RUS77667.1 - 3.1e-08 33.2 4.5 1.1e-07 31.5 1.0 2.7 2 0 0 2 2 2 2 PQ loop repeat FKBP_C PF00254.28 RUS77669.1 - 2.8e-35 120.5 0.0 3.5e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-AN1 PF01428.16 RUS77670.1 - 7e-08 32.5 10.1 2e-07 31.0 10.1 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger zf-A20 PF01754.16 RUS77670.1 - 8.2e-05 22.5 3.6 0.00021 21.2 3.6 1.8 1 0 0 1 1 1 1 A20-like zinc finger TPR_12 PF13424.6 RUS77671.1 - 7.3e-08 32.6 3.7 0.00042 20.5 1.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Consortin_C PF15281.6 RUS77671.1 - 0.00026 21.0 0.2 0.00054 19.9 0.2 1.5 1 0 0 1 1 1 1 Consortin C-terminus TPR_8 PF13181.6 RUS77671.1 - 0.00047 20.1 4.5 0.15 12.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS77671.1 - 0.00062 19.5 8.2 0.054 13.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PspA_IM30 PF04012.12 RUS77671.1 - 0.00086 18.9 1.1 0.0018 17.9 1.1 1.5 1 0 0 1 1 1 1 PspA/IM30 family TPR_2 PF07719.17 RUS77671.1 - 0.00092 19.2 7.8 0.058 13.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS77671.1 - 0.0064 16.4 1.7 0.018 15.0 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS77671.1 - 0.06 13.2 2.3 0.24 11.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SMI1_KNR4 PF09346.10 RUS77671.1 - 0.073 13.5 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) DUF4658 PF15555.6 RUS77671.1 - 0.11 12.6 2.7 0.39 10.9 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4658) Orf78 PF06024.12 RUS77671.1 - 0.12 12.6 0.7 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Pellino PF04710.14 RUS77672.1 - 5.2e-192 638.0 0.0 6e-192 637.8 0.0 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 RUS77672.1 - 2.1e-05 24.3 6.4 0.03 14.2 0.1 3.2 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS77672.1 - 0.0071 16.7 6.1 0.55 10.6 0.2 2.6 2 0 0 2 2 2 2 Ring finger domain zf-Di19 PF05605.12 RUS77672.1 - 0.0087 16.3 1.4 0.86 9.9 0.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 RUS77672.1 - 0.018 14.9 0.3 0.018 14.9 0.3 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS77672.1 - 0.051 13.4 7.1 3.8 7.4 0.6 3.4 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS77672.1 - 0.056 13.4 6.3 0.7 9.9 0.1 3.1 2 1 0 2 2 2 0 zinc-RING finger domain TPD PF14811.6 RUS77674.1 - 1e-05 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif ACCA PF03255.14 RUS77674.1 - 0.061 13.2 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPD PF14811.6 RUS77675.1 - 1.7e-37 128.4 0.3 2.5e-37 127.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Sushi PF00084.20 RUS77677.1 - 1.4e-25 89.6 30.0 2.6e-08 34.3 0.5 5.6 5 0 0 5 5 5 5 Sushi repeat (SCR repeat) cEGF PF12662.7 RUS77677.1 - 0.0029 17.5 11.1 0.64 10.0 0.1 4.7 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS77677.1 - 1.8 8.9 10.0 0.54 10.6 3.1 3.5 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Glyco_transf_49 PF13896.6 RUS77678.1 - 6.7e-97 324.8 0.3 1.1e-96 324.0 0.3 1.3 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Lectin_C PF00059.21 RUS77679.1 - 1.6e-16 61.0 2.8 2.6e-16 60.3 2.8 1.4 1 0 0 1 1 1 1 Lectin C-type domain TGFb_propeptide PF00688.18 RUS77680.1 - 0.00024 21.0 0.1 0.00032 20.5 0.1 1.1 1 0 0 1 1 1 1 TGF-beta propeptide DUF4042 PF13251.6 RUS77680.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DUF4695 PF15766.5 RUS77682.1 - 0.0096 16.1 0.6 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4695) ORC6 PF05460.13 RUS77682.1 - 1.6 7.9 15.4 2.2 7.4 15.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Gelsolin PF00626.22 RUS77684.1 - 2.7e-24 84.8 0.0 2.6e-05 24.0 0.0 5.7 5 1 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 RUS77684.1 - 3.2e-15 55.9 0.6 3.2e-15 55.9 0.6 2.5 2 0 0 2 2 2 1 Villin headpiece domain GRASP55_65 PF04495.14 RUS77685.1 - 1.5e-73 245.6 0.0 3.5e-54 182.9 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 RUS77685.1 - 4.9e-09 36.4 0.0 0.00014 22.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS77685.1 - 4e-07 29.8 0.1 0.021 14.7 0.0 2.8 2 2 0 2 2 2 2 PDZ domain Guanylate_kin PF00625.21 RUS77686.1 - 1.9e-63 213.4 0.0 2.4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 RUS77686.1 - 2.6e-06 27.5 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RUS77686.1 - 2.9e-05 24.6 0.0 9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS77686.1 - 0.00013 22.2 0.0 0.0026 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS77686.1 - 0.00015 22.2 0.0 0.0003 21.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RUS77686.1 - 0.00021 21.5 0.0 0.0018 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RUS77686.1 - 0.00022 21.2 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 RUS77686.1 - 0.00031 20.4 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 RUS77686.1 - 0.00061 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 RUS77686.1 - 0.0014 18.3 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RUS77686.1 - 0.0036 17.8 0.2 0.0096 16.4 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 RUS77686.1 - 0.0056 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 RUS77686.1 - 0.0068 16.3 0.1 0.33 10.8 0.0 2.3 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_23 PF13476.6 RUS77686.1 - 0.011 16.3 0.6 0.018 15.5 0.6 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RUS77686.1 - 0.013 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 RUS77686.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 RUS77686.1 - 0.024 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS77686.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 RUS77686.1 - 0.036 13.3 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 RUS77686.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 RUS77686.1 - 0.06 12.1 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 RUS77686.1 - 0.068 12.4 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 RUS77686.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 RUS77686.1 - 0.075 13.5 0.1 0.72 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RUS77686.1 - 0.08 12.6 0.0 9.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase Apolipoprotein PF01442.18 RUS77686.1 - 0.09 12.6 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain AAA_24 PF13479.6 RUS77686.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 RUS77686.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain UMPH-1 PF05822.12 RUS77687.1 - 1e-89 300.3 0.2 1.2e-89 300.1 0.2 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 RUS77687.1 - 0.031 14.3 0.0 0.79 9.8 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS77687.1 - 0.049 14.0 0.0 0.079 13.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Arm PF00514.23 RUS77688.1 - 2e-45 151.5 29.5 3.2e-07 30.2 0.2 11.8 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 RUS77688.1 - 4e-11 42.2 2.8 1.1e-06 27.5 1.9 3.3 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.6 RUS77688.1 - 5.2e-07 30.0 10.8 6.5e-05 23.2 0.5 5.2 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 RUS77688.1 - 1.5e-06 28.4 3.7 0.018 15.1 0.4 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 RUS77688.1 - 5.2e-05 23.2 3.6 0.19 11.7 0.1 3.9 3 1 2 5 5 5 2 Domain of unknown function (DUF3361) Arm_2 PF04826.13 RUS77688.1 - 5.7e-05 22.7 5.3 0.0084 15.6 1.1 4.2 4 1 2 6 6 6 1 Armadillo-like HEAT PF02985.22 RUS77688.1 - 8.5e-05 22.5 9.6 1.1 9.7 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 RUS77688.1 - 0.0001 22.7 11.5 0.75 10.4 0.6 5.6 4 1 1 5 5 5 2 HEAT-like repeat KAP PF05804.12 RUS77688.1 - 0.00027 19.2 7.2 0.018 13.2 1.3 2.9 2 1 1 4 4 4 3 Kinesin-associated protein (KAP) Pes-10 PF07149.11 RUS77688.1 - 0.0035 16.5 0.7 2.3 7.2 0.0 2.4 2 1 0 2 2 2 2 Pes-10 RasGEF_N_2 PF14663.6 RUS77688.1 - 0.0038 17.6 5.0 35 4.8 0.0 4.9 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 RUS77688.1 - 0.004 17.2 3.3 0.024 14.6 0.1 3.4 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain T3SS_ExsE PF18286.1 RUS77690.1 - 1.4e-06 28.1 22.5 27 4.8 0.1 11.4 2 2 9 12 12 12 8 Type III secretion system ExsE T3SS_ExsE PF18286.1 RUS77691.1 - 4.9e-08 32.8 33.0 23 5.0 0.1 14.1 3 2 14 17 17 17 11 Type III secretion system ExsE SEA PF01390.20 RUS77692.1 - 2.3e-09 37.3 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 SEA domain DUF1180 PF06679.12 RUS77693.1 - 0.013 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RUS77693.1 - 0.015 15.2 0.5 1.7 8.6 0.0 2.4 1 1 2 3 3 3 0 TMEM154 protein family EphA2_TM PF14575.6 RUS77693.1 - 0.063 14.2 0.0 0.08 13.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.6 RUS77693.1 - 0.068 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Herpes_gE PF02480.16 RUS77693.1 - 0.074 11.8 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 RUS77693.1 - 0.097 12.9 0.5 0.17 12.1 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) MLANA PF14991.6 RUS77693.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A 7tm_1 PF00001.21 RUS77694.1 - 2.4e-51 174.6 20.3 3.2e-51 174.2 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS77694.1 - 3.1e-09 36.9 15.3 6.2e-09 35.9 15.3 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS77694.1 - 4.2e-05 23.4 8.7 4.2e-05 23.4 8.7 2.2 2 1 0 2 2 2 1 Olfactory receptor Git3 PF11710.8 RUS77694.1 - 0.01 15.6 7.5 0.01 15.6 7.5 2.6 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 DUF4577 PF15145.6 RUS77694.1 - 0.34 10.9 1.0 0.75 9.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF805 PF05656.14 RUS77694.1 - 2.4 8.6 0.0 2.4 8.6 0.0 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) OMP_b-brl_3 PF14905.6 RUS77695.1 - 0.0078 15.2 4.3 0.0096 14.9 4.3 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family DUF3996 PF13161.6 RUS77695.1 - 0.016 14.9 5.0 0.15 11.8 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3996) Smoothelin PF12510.8 RUS77696.1 - 4.6e-10 39.4 11.5 23 5.1 0.0 10.6 1 1 13 14 14 14 1 Smoothelin cytoskeleton protein HicA_toxin PF07927.12 RUS77696.1 - 3.5e-07 30.2 0.4 5.6 7.1 0.0 8.5 2 2 4 6 6 6 1 HicA toxin of bacterial toxin-antitoxin, DUF2007 PF09413.10 RUS77696.1 - 0.28 11.4 25.8 58 3.9 0.1 8.7 2 2 10 12 12 12 0 Putative prokaryotic signal transducing protein Phenyl_P_gamma PF09662.10 RUS77696.1 - 0.45 10.7 13.5 33 4.7 0.1 6.8 1 1 5 7 7 7 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DegT_DnrJ_EryC1 PF01041.17 RUS77696.1 - 5.9 6.1 6.8 5 6.3 1.0 3.0 2 1 3 5 5 5 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ntox8 PF15545.6 RUS77697.1 - 0.012 15.7 6.8 32 4.7 6.8 3.1 1 1 0 1 1 1 0 Bacterial toxin 8 Ntox33 PF15533.6 RUS77697.1 - 0.042 14.3 9.1 18 5.9 0.1 3.7 1 1 2 3 3 3 0 Bacterial toxin 33 DUF1905 PF08922.11 RUS77697.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) S-layer PF07752.11 RUS77697.1 - 0.095 11.7 0.3 20 4.1 0.1 3.1 1 1 1 2 2 2 0 S-layer protein tRNA-synt_1c_C PF03950.18 RUS77697.1 - 0.14 12.0 0.5 15 5.4 0.3 2.9 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain TPR_1 PF00515.28 RUS77698.1 - 4.3e-08 32.6 0.0 0.0026 17.5 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77698.1 - 8.6e-07 28.6 0.1 0.078 13.1 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat BUD22 PF09073.10 RUS77698.1 - 4.9e-06 26.1 16.1 6.5e-06 25.7 16.1 1.1 1 0 0 1 1 1 1 BUD22 TPR_16 PF13432.6 RUS77698.1 - 5e-06 27.1 0.2 1e-05 26.1 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS77698.1 - 1.4e-05 25.1 1.2 6.1e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77698.1 - 9.4e-05 22.0 0.2 0.00017 21.2 0.2 1.4 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 RUS77698.1 - 0.00018 22.0 0.1 0.00038 20.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat COPI_C PF06957.11 RUS77698.1 - 0.00043 19.2 0.7 0.00084 18.2 0.7 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus DUF2052 PF09747.9 RUS77698.1 - 0.0027 17.9 6.0 0.0027 17.9 6.0 2.2 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) TPR_8 PF13181.6 RUS77698.1 - 0.003 17.6 0.0 1.2 9.6 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS77698.1 - 0.0033 17.4 0.2 0.18 11.9 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS77698.1 - 0.0049 17.1 0.1 1.3 9.4 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS77698.1 - 0.0087 16.8 0.1 0.84 10.6 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat FAM60A PF15396.6 RUS77698.1 - 0.032 14.2 13.3 0.045 13.7 13.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TPR_9 PF13371.6 RUS77698.1 - 0.034 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF913 PF06025.12 RUS77698.1 - 0.034 13.1 7.7 0.045 12.7 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RUS77698.1 - 0.048 12.4 11.8 0.056 12.2 11.8 1.1 1 0 0 1 1 1 0 Presenilin YL1 PF05764.13 RUS77698.1 - 0.11 12.5 32.6 0.08 13.0 5.7 2.1 2 0 0 2 2 2 0 YL1 nuclear protein RNA_pol_3_Rpc31 PF11705.8 RUS77698.1 - 0.14 12.4 32.3 0.075 13.3 29.8 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Rtf2 PF04641.12 RUS77698.1 - 0.14 11.5 22.3 0.24 10.7 22.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Goodbye PF17109.5 RUS77698.1 - 0.27 11.7 0.1 0.27 11.7 0.1 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Gti1_Pac2 PF09729.9 RUS77698.1 - 0.4 10.8 11.5 0.65 10.1 11.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family FAM176 PF14851.6 RUS77698.1 - 0.57 9.8 20.1 1 9.0 8.5 2.3 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 RUS77698.1 - 1.6 8.7 23.9 0.96 9.5 6.4 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal SLC12 PF03522.15 RUS77698.1 - 3.2 6.7 11.9 4.4 6.2 11.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Eapp_C PF10238.9 RUS77698.1 - 3.4 7.7 18.2 2.9 7.9 1.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein CPSF100_C PF13299.6 RUS77698.1 - 5.4 7.2 20.0 0.66 10.1 3.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 RUS77698.1 - 9.6 6.9 23.5 1.8 9.3 7.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) S_100 PF01023.19 RUS77699.1 - 6.8e-07 28.9 16.7 3.8 7.3 0.3 6.2 1 1 9 10 10 10 8 S-100/ICaBP type calcium binding domain PI3Ka PF00613.20 RUS77699.1 - 0.00047 19.6 0.7 5.4 6.4 0.0 3.2 1 1 2 3 3 3 3 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sdh5 PF03937.16 RUS77699.1 - 0.0024 17.8 13.2 0.57 10.2 0.2 4.0 1 1 3 4 4 4 1 Flavinator of succinate dehydrogenase TetR_C_4 PF08359.11 RUS77699.1 - 0.0096 16.1 7.3 1.2 9.3 0.3 3.3 1 1 1 2 2 2 2 YsiA-like protein, C-terminal region DUF3900 PF13039.6 RUS77699.1 - 0.015 15.3 1.4 1.5 8.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3900) TryThrA_C PF12319.8 RUS77699.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF1647 PF07801.11 RUS77699.1 - 0.021 14.6 4.5 6.6 6.5 1.6 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1647) WI12 PF07107.11 RUS77699.1 - 0.059 13.5 5.3 94 3.2 2.7 4.9 1 1 1 2 2 2 0 Wound-induced protein WI12 Phage_CRI PF05144.14 RUS77699.1 - 0.066 12.5 12.9 1.3e+02 1.7 12.9 3.2 1 1 0 1 1 1 0 Phage replication protein CRI DUF2345 PF10106.9 RUS77699.1 - 0.08 12.8 0.2 0.3 10.9 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) NAAA-beta PF15508.6 RUS77699.1 - 0.12 12.7 0.0 14 6.0 0.0 2.6 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Mannitol_dh_C PF08125.13 RUS77699.1 - 0.29 10.6 3.3 6.2 6.2 0.2 2.2 1 1 1 2 2 2 0 Mannitol dehydrogenase C-terminal domain VSG_B PF13206.6 RUS77699.1 - 0.8 8.9 5.3 25 4.0 5.3 2.4 1 1 0 1 1 1 0 Trypanosomal VSG domain DehI PF10778.9 RUS77699.1 - 1.5 9.0 6.9 12 6.0 6.6 2.1 1 1 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI 7tm_1 PF00001.21 RUS77700.1 - 5.3e-13 48.9 7.6 8.4e-13 48.2 7.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Plasmodium_HRP PF05403.11 RUS77700.1 - 0.0047 16.8 3.8 0.0075 16.1 3.8 1.2 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) LRR_4 PF12799.7 RUS77701.1 - 0.0015 18.9 7.5 1.7 9.2 1.9 3.9 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS77701.1 - 0.0026 18.1 12.1 7.6 7.5 1.6 5.7 6 0 0 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 RUS77701.1 - 0.04 13.8 2.2 0.056 13.3 0.2 2.3 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 RUS77701.1 - 0.5 10.6 8.1 33 4.9 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat 7tm_1 PF00001.21 RUS77702.1 - 6.5e-06 25.7 8.2 6.5e-06 25.7 8.2 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS77702.1 - 1.6 8.3 12.3 11 5.6 12.3 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx CLIP PF12032.8 RUS77703.1 - 4.6 7.6 15.8 26 5.2 0.1 5.7 1 1 5 6 6 6 0 Regulatory CLIP domain of proteinases 7tm_1 PF00001.21 RUS77704.1 - 3.1e-06 26.7 0.0 6e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RabGAP-TBC PF00566.18 RUS77706.1 - 2.2e-46 158.2 0.7 3.2e-46 157.7 0.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 RUS77706.1 - 5.3e-34 117.1 0.1 1.2e-33 116.0 0.1 1.6 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 RUS77706.1 - 9.3e-12 44.4 0.1 1.9e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS77706.1 - 3.1e-10 39.6 0.0 6.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS77706.1 - 1e-09 38.1 0.0 2.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CDK2AP PF09806.9 RUS77707.1 - 0.71 9.9 2.2 0.92 9.5 2.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Lig_chan PF00060.26 RUS77708.1 - 1.1e-28 100.0 0.0 1.7e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS77708.1 - 7.4e-28 97.5 0.0 1.6e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 RUS77708.1 - 1.6e-21 76.6 0.0 6e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RUS77708.1 - 2.7e-17 62.9 0.3 2.3e-15 56.6 0.0 2.7 2 1 0 2 2 2 1 Receptor family ligand binding region 5_nucleotid PF05761.14 RUS77709.1 - 1.8e-61 208.4 0.0 2.1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family SH3_9 PF14604.6 RUS77710.1 - 4.8e-17 61.6 1.5 3.1e-07 30.2 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 RUS77710.1 - 4.2e-16 58.4 0.0 7.6e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain fn3 PF00041.21 RUS77710.1 - 0.00017 21.9 0.0 0.00067 20.0 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain SH3_1 PF00018.28 RUS77710.1 - 0.0002 20.9 0.0 0.37 10.4 0.0 2.8 2 0 0 2 2 2 2 SH3 domain C2 PF00168.30 RUS77714.1 - 6.9e-71 235.1 1.9 2.4e-23 82.4 0.0 3.9 4 0 0 4 4 4 3 C2 domain PRT_C PF08372.10 RUS77714.1 - 4.2e-12 46.1 0.6 2.7e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 RUS77714.1 - 3.9e-06 26.1 1.6 6e-06 25.5 1.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 RUS77714.1 - 1.2e-05 24.9 1.9 0.00095 18.6 1.9 2.3 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) MLVIN_C PF18697.1 RUS77714.1 - 0.00076 19.5 0.8 1.8 8.7 0.1 3.3 3 0 0 3 3 3 2 Murine leukemia virus (MLV) integrase (IN) C-terminal domain 2OG-FeII_Oxy_4 PF13661.6 RUS77714.1 - 0.047 14.4 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ribosomal_L36e PF01158.18 RUS77716.1 - 1.3e-40 137.5 7.9 1.5e-40 137.3 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 RUS77716.1 - 0.032 14.1 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF234 PF03008.14 RUS77716.1 - 0.13 12.7 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function ELMO_CED12 PF04727.13 RUS77717.1 - 1.4e-33 116.5 0.0 2.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Pox_A_type_inc PF04508.12 RUS77718.1 - 0.23 11.4 0.0 0.23 11.4 0.0 7.7 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat DIX PF00778.17 RUS77719.1 - 4.6e-22 77.6 0.0 7.1e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 DIX domain Axin_b-cat_bind PF08833.10 RUS77719.1 - 5.8e-07 29.5 0.6 2.3e-06 27.6 0.6 2.1 1 0 0 1 1 1 1 Axin beta-catenin binding domain Glyco_hydro_18 PF00704.28 RUS77722.1 - 1.6e-77 261.3 0.3 1.8e-77 261.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 RUS77723.1 - 1.8e-05 24.8 9.6 1.8e-05 24.8 9.6 1.8 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain SlyX PF04102.12 RUS77726.1 - 0.015 15.9 1.4 0.015 15.9 1.4 4.8 3 1 1 4 4 4 0 SlyX Seadorna_VP6 PF07407.11 RUS77726.1 - 0.029 13.3 5.1 0.32 9.9 0.1 2.1 2 0 0 2 2 2 0 Seadornavirus VP6 protein ZapB PF06005.12 RUS77726.1 - 0.11 13.0 28.5 0.51 10.8 1.5 4.7 3 1 1 4 4 4 0 Cell division protein ZapB VGPC1_C PF16799.5 RUS77726.1 - 0.47 10.5 8.5 0.67 10.0 1.7 2.8 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 IQ PF00612.27 RUS77726.1 - 0.5 10.3 21.6 1.7 8.6 0.5 4.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif YabA PF06156.13 RUS77726.1 - 0.68 10.6 25.5 0.63 10.7 4.6 4.3 1 1 3 4 4 4 0 Initiation control protein YabA Prefoldin_2 PF01920.20 RUS77726.1 - 4.6 7.3 22.5 0.74 9.8 5.7 3.6 3 0 0 3 3 3 0 Prefoldin subunit Pyridoxal_deC PF00282.19 RUS77727.1 - 3.2e-57 194.0 0.0 3.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RUS77727.1 - 2.8e-05 23.6 0.0 4.9e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RUS77727.1 - 0.0044 16.0 0.0 0.0068 15.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DSL PF01414.19 RUS77728.1 - 1.6e-08 34.7 0.9 2.8e-08 33.9 0.9 1.3 1 0 0 1 1 1 1 Delta serrate ligand VHP PF02209.19 RUS77728.1 - 0.0029 17.6 0.5 3.3 7.9 0.1 2.3 2 0 0 2 2 2 2 Villin headpiece domain DUF4448 PF14610.6 RUS77728.1 - 0.003 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 RUS77728.1 - 0.038 13.4 0.5 0.072 12.5 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 RUS77728.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4366 PF14283.6 RUS77728.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MT-A70 PF05063.14 RUS77729.1 - 6.4e-58 195.5 0.2 1.1e-57 194.7 0.0 1.5 2 0 0 2 2 2 1 MT-A70 CHCH PF06747.13 RUS77730.1 - 2.3e-08 34.0 5.9 3.5e-08 33.4 5.9 1.3 1 0 0 1 1 1 1 CHCH domain Colipase-like PF15083.6 RUS77730.1 - 0.028 14.5 1.2 0.042 14.0 1.2 1.3 1 0 0 1 1 1 0 Colipase-like ELFV_dehydrog PF00208.21 RUS77730.1 - 0.095 12.4 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UCR_hinge PF02320.16 RUS77730.1 - 0.2 11.9 3.7 3.2 8.0 0.2 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein 7tm_1 PF00001.21 RUS77732.1 - 9.2e-43 146.4 18.6 1.3e-42 146.0 18.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS77732.1 - 1.4e-05 24.7 14.6 0.0018 17.7 14.6 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS77732.1 - 0.0012 18.5 14.7 0.0012 18.5 14.7 2.4 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4692 PF15763.5 RUS77732.1 - 0.038 14.5 1.1 0.073 13.5 1.1 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Med31 PF05669.12 RUS77732.1 - 0.77 9.8 2.9 2.3 8.3 2.9 1.7 1 0 0 1 1 1 0 SOH1 DUF775 PF05603.12 RUS77733.1 - 4.5e-57 192.8 0.8 6.4e-57 192.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Thiolase_N PF00108.23 RUS77734.1 - 3.5e-39 134.7 0.1 4e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 RUS77734.1 - 6.9e-05 22.5 0.6 0.00024 20.8 0.6 1.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF1576 PF07613.11 RUS77734.1 - 0.075 12.6 1.0 0.1 12.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Sugar_tr PF00083.24 RUS77735.1 - 4.6e-11 42.3 0.3 5.4e-11 42.0 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS77735.1 - 0.0034 16.3 1.3 0.0042 16.1 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS77736.1 - 9.7e-14 51.1 6.3 9.8e-14 51.1 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 RUS77737.1 - 2.5e-58 198.0 4.2 3e-58 197.8 4.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS77737.1 - 1.4e-20 73.5 8.8 1.8e-20 73.2 8.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 RUS77737.1 - 0.00033 19.7 1.9 0.00038 19.5 1.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 RUS77737.1 - 0.024 13.0 7.2 0.028 12.8 7.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector DUF4911 PF16256.5 RUS77737.1 - 0.097 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Phage_holin_3_2 PF04550.12 RUS77737.1 - 0.11 13.0 5.5 0.097 13.2 3.0 2.2 1 1 0 1 1 1 0 Phage holin family 2 Bcr-Abl_Oligo PF09036.10 RUS77737.1 - 0.13 12.2 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain NADH-u_ox-rdase PF10785.9 RUS77737.1 - 0.95 10.2 3.1 28 5.5 0.0 2.8 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Sugar_tr PF00083.24 RUS77738.1 - 2.1e-06 26.9 1.2 3.2e-06 26.3 0.2 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter SSF PF00474.17 RUS77738.1 - 0.12 11.2 0.1 0.12 11.2 0.1 1.6 2 0 0 2 2 2 0 Sodium:solute symporter family EI24 PF07264.11 RUS77738.1 - 4.2 7.6 9.1 6.2 7.0 9.1 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Sugar_tr PF00083.24 RUS77739.1 - 1.7e-18 66.8 7.6 2.1e-18 66.4 7.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter rve PF00665.26 RUS77740.1 - 1.5e-17 63.9 0.0 3.9e-17 62.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 RUS77740.1 - 6.7e-06 25.8 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 RUS77740.1 - 0.038 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_Tnp_IS240 PF13610.6 RUS77740.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 DDE domain DUF2464 PF10240.9 RUS77741.1 - 4e-67 226.5 0.0 4.8e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Multivesicular body subunit 12 zf-CCHC PF00098.23 RUS77742.1 - 4.9e-05 23.2 11.1 0.0033 17.4 1.0 2.8 2 1 0 2 2 2 2 Zinc knuckle Asp_protease_2 PF13650.6 RUS77742.1 - 0.00067 20.3 0.2 0.0018 18.8 0.2 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 RUS77742.1 - 0.0038 17.5 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RUS77742.1 - 0.0049 17.4 0.4 0.011 16.3 0.4 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RE_ApaLI PF09499.10 RUS77742.1 - 0.054 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease zf-CCHC_3 PF13917.6 RUS77742.1 - 0.078 13.0 0.5 0.2 11.6 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 RUS77743.1 - 7.4e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 RUS77745.1 - 1.8e-22 79.6 0.0 3.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS77745.1 - 2e-18 66.3 0.0 5.5e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77745.1 - 1.1e-13 51.2 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS77745.1 - 2.5e-12 46.7 1.5 6e-12 45.5 1.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Glyco_transf_92 PF01697.27 RUS77748.1 - 6.9e-32 111.1 0.0 1.2e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 TMEM154 PF15102.6 RUS77749.1 - 0.0064 16.4 0.2 0.01 15.7 0.2 1.3 1 0 0 1 1 1 1 TMEM154 protein family CcmD PF04995.14 RUS77749.1 - 0.019 15.1 1.3 0.032 14.3 1.3 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SIT PF15330.6 RUS77749.1 - 0.02 15.3 0.1 0.032 14.7 0.1 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Adeno_E3_CR2 PF02439.15 RUS77749.1 - 0.068 12.9 2.7 0.13 12.1 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 RUS77749.1 - 0.1 13.5 0.0 0.15 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Endomucin PF07010.12 RUS77749.1 - 0.11 12.4 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Endomucin TMEM132D_C PF15706.5 RUS77749.1 - 0.2 11.4 0.5 0.34 10.7 0.5 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4381 PF14316.6 RUS77749.1 - 0.21 11.8 0.3 0.3 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4519 PF15012.6 RUS77749.1 - 1.2 9.3 6.1 2.4 8.4 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF5358 PF17311.2 RUS77750.1 - 0.88 9.6 14.9 4.6 7.2 4.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5358) Bacteroid_pep PF14406.6 RUS77750.1 - 2.1 8.8 22.4 62 4.1 0.4 6.0 1 1 5 6 6 6 0 Ribosomally synthesized peptide in Bacteroidetes DUF2345 PF10106.9 RUS77750.1 - 3 7.7 30.3 22 4.9 4.5 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2345) Ets PF00178.22 RUS77751.1 - 8.4e-24 83.8 0.4 1.4e-23 83.2 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Somatomedin_B PF01033.17 RUS77752.1 - 0.0014 19.0 15.6 0.0014 19.0 15.6 2.4 2 0 0 2 2 2 1 Somatomedin B domain APC1_C PF18122.1 RUS77752.1 - 0.02 14.8 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Herpeto_peptide PF14409.6 RUS77753.1 - 1.4e-10 41.2 22.9 0.15 12.3 0.2 6.3 1 1 6 7 7 7 7 Ribosomally synthesized peptide in Herpetosiphon Rota_VP4_MID PF17477.2 RUS77753.1 - 0.17 11.2 0.9 2.7 7.3 0.2 2.2 1 1 1 2 2 2 0 Rotavirus VP4 membrane interaction domain SsgA PF04686.12 RUS77754.1 - 0.029 14.4 0.8 24 5.0 0.1 3.0 1 1 3 4 4 4 0 Streptomyces sporulation and cell division protein, SsgA SIP1 PF04938.12 RUS77754.1 - 0.26 11.0 4.5 15 5.2 4.5 2.7 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) ATP-synt_G PF04718.15 RUS77754.1 - 0.26 12.1 0.2 8.6 7.3 0.2 2.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit Tetraspanin PF00335.20 RUS77755.1 - 7.3e-19 68.4 2.9 5.9e-10 39.2 0.3 2.1 1 1 1 2 2 2 2 Tetraspanin family MFS_5 PF05631.14 RUS77757.1 - 2e-76 257.2 13.9 2.8e-76 256.7 13.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Amidohydro_1 PF01979.20 RUS77758.1 - 2e-27 96.4 0.5 6.3e-27 94.8 0.5 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RUS77758.1 - 2e-14 53.9 0.2 3e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family AIG1 PF04548.16 RUS77762.1 - 2.6e-36 124.9 0.3 4.2e-36 124.3 0.3 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS77762.1 - 5.2e-06 26.5 0.4 1.7e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RUS77762.1 - 0.0048 17.0 0.1 0.0048 17.0 0.1 2.2 3 1 0 3 3 3 1 Dynamin family AAA_7 PF12775.7 RUS77762.1 - 0.0051 16.3 0.4 0.01 15.4 0.4 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 RUS77762.1 - 0.015 14.6 0.2 0.037 13.3 0.2 1.6 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 RUS77762.1 - 0.032 14.7 0.2 1.7 9.2 0.1 2.5 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 RUS77762.1 - 0.038 14.2 0.2 0.1 12.9 0.2 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 RUS77762.1 - 0.05 13.3 0.9 0.077 12.7 0.1 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 RUS77762.1 - 0.092 13.1 0.3 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 RUS77762.1 - 0.094 12.6 1.1 0.27 11.1 1.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 RUS77762.1 - 0.13 12.7 0.6 0.89 10.0 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RUS77762.1 - 0.34 11.4 2.4 0.78 10.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 RUS77763.1 - 5.7 7.6 10.3 0.44 11.1 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type PIN_11 PF18479.1 RUS77764.1 - 4.1e-23 81.8 0.0 7.9e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 PIN like domain PIN7 PF18475.1 RUS77764.1 - 0.0013 19.3 0.0 0.0052 17.4 0.0 2.1 1 0 0 1 1 1 1 PIN domain Crp PF00325.20 RUS77765.1 - 0.099 12.3 0.1 48 3.7 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, crp family TMEM65 PF10507.9 RUS77766.1 - 2e-46 156.4 0.3 4.2e-46 155.4 0.3 1.6 1 0 0 1 1 1 1 Transmembrane protein 65 Sigma70_ner PF04546.13 RUS77767.1 - 6.8e-07 29.4 2.9 6.8e-07 29.4 2.9 2.2 1 1 1 2 2 2 1 Sigma-70, non-essential region CDC45 PF02724.14 RUS77767.1 - 0.71 8.1 72.7 0.41 8.9 27.4 2.1 1 1 1 2 2 2 0 CDC45-like protein Skp1_POZ PF03931.15 RUS77768.1 - 3.6e-11 43.0 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF4508 PF14969.6 RUS77769.1 - 9.3e-34 115.6 3.2 1.1e-33 115.4 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Beta-TrCP_D PF12125.8 RUS77769.1 - 0.2 11.6 3.5 11 6.1 0.4 2.5 2 0 0 2 2 2 0 D domain of beta-TrCP Cupin_4 PF08007.12 RUS77770.1 - 5.5e-66 223.2 0.0 8.4e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 RUS77770.1 - 1.5e-08 34.7 0.6 2.6e-06 27.4 0.6 3.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 RUS77770.1 - 0.0011 18.7 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Cupin domain DUF438 PF04282.13 RUS77770.1 - 0.14 12.2 0.0 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF438) AraC_binding PF02311.19 RUS77770.1 - 0.17 11.8 0.1 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain Ndc1_Nup PF09531.10 RUS77770.1 - 5.5 5.6 7.7 7 5.2 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DLH PF01738.18 RUS77771.1 - 5.8e-42 143.7 0.0 6.5e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 RUS77771.1 - 5.9e-07 29.2 0.5 0.021 14.3 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RUS77771.1 - 0.0032 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 RUS77771.1 - 0.0058 16.6 0.8 1.7 8.5 0.1 2.9 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 RUS77771.1 - 0.025 14.3 0.4 0.15 11.7 0.4 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) AXE1 PF05448.12 RUS77771.1 - 0.14 10.8 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.28 RUS77772.1 - 5.5e-52 176.8 0.0 7.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS77772.1 - 0.0019 19.1 0.6 0.022 15.7 0.8 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DDE_3 PF13358.6 RUS77772.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease ANF_receptor PF01094.28 RUS77774.1 - 4.3e-19 68.8 0.0 7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS77774.1 - 0.00036 20.3 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 RUS77775.1 - 1.3e-24 87.0 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region CBP4 PF07960.11 RUS77775.1 - 0.027 14.3 4.2 0.044 13.6 4.2 1.3 1 0 0 1 1 1 0 CBP4 Calcyon PF06387.11 RUS77775.1 - 0.071 13.1 1.2 0.16 11.9 1.2 1.6 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Peripla_BP_6 PF13458.6 RUS77775.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Presenilin PF01080.17 RUS77775.1 - 0.4 9.4 1.9 0.62 8.8 1.9 1.3 1 0 0 1 1 1 0 Presenilin U1snRNP70_N PF12220.8 RUS77775.1 - 4.2 8.1 8.3 0.6 10.8 2.6 2.3 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ANF_receptor PF01094.28 RUS77776.1 - 2.1e-07 30.4 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region GATA PF00320.27 RUS77777.1 - 0.097 12.3 5.4 2.4e+02 1.4 0.6 6.7 7 1 1 8 8 8 0 GATA zinc finger ANF_receptor PF01094.28 RUS77778.1 - 2.8e-58 197.7 0.1 3.7e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS77778.1 - 1.4e-07 31.5 0.0 0.006 16.3 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Pkinase_Tyr PF07714.17 RUS77778.1 - 2.3e-06 27.1 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS77778.1 - 0.0003 20.2 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SP_C-Propep PF08999.10 RUS77778.1 - 0.099 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Herpes_UL73 PF03554.13 RUS77778.1 - 0.89 9.6 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein HTH_49 PF18010.1 RUS77779.1 - 1.7e-08 34.0 1.6 98 3.0 0.0 9.0 1 1 11 12 12 12 0 Cry35Ab1 HTH C-terminal domain HC2 PF07382.11 RUS77779.1 - 0.00011 22.3 20.2 0.00013 22.1 20.2 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 T3SchapCesA PF11439.8 RUS77779.1 - 0.00044 20.3 1.4 1.7 8.9 0.2 3.5 1 1 2 3 3 3 3 Type III secretion system filament chaperone CesA Kinesin PF00225.23 RUS77781.1 - 6.3e-19 68.1 0.0 8.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS77781.1 - 7.1e-15 55.2 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding mono-CXXC PF15626.6 RUS77781.1 - 0.61 10.5 5.3 0.31 11.4 0.8 2.7 2 1 0 3 3 3 0 single CXXC unit Kinesin PF00225.23 RUS77782.1 - 3.5e-37 128.1 0.7 3.5e-32 111.6 0.0 2.5 3 0 0 3 3 3 2 Kinesin motor domain Kinesin_assoc PF16183.5 RUS77782.1 - 0.015 15.4 1.9 0.029 14.5 1.9 1.5 1 0 0 1 1 1 0 Kinesin-associated PspB PF06667.12 RUS77782.1 - 0.21 11.7 1.0 0.54 10.3 1.0 1.7 1 0 0 1 1 1 0 Phage shock protein B bZIP_1 PF00170.21 RUS77782.1 - 1.3 9.2 15.5 4.6 7.4 0.6 4.3 3 1 1 4 4 4 0 bZIP transcription factor HALZ PF02183.18 RUS77782.1 - 1.8 8.9 11.5 25 5.2 1.0 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper YabA PF06156.13 RUS77782.1 - 4.8 7.9 19.4 9.9 6.9 2.1 3.0 2 1 1 3 3 3 0 Initiation control protein YabA CCDC92 PF14916.6 RUS77782.1 - 7.8 6.4 14.4 0.4 10.5 1.1 3.2 1 1 2 3 3 3 0 Coiled-coil domain of unknown function MFS_1 PF07690.16 RUS77784.1 - 0.00026 20.0 0.1 0.00038 19.5 0.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_ICP4_C PF03585.14 RUS77784.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region Sigma54_AID PF00309.20 RUS77785.1 - 0.052 13.4 0.4 0.082 12.8 0.4 1.2 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) ETRAMP PF09716.10 RUS77785.1 - 0.08 13.0 7.0 0.14 12.3 7.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OAD_gamma PF04277.13 RUS77785.1 - 6.5 7.4 6.5 12 6.5 6.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_transf_10 PF00852.19 RUS77786.1 - 1.9e-44 151.5 2.7 3.1e-44 150.8 2.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS77786.1 - 6.9e-09 36.1 0.2 7.9e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal CotJB PF12652.7 RUS77786.1 - 0.25 11.6 2.4 3 8.1 2.4 2.6 1 1 0 1 1 1 0 CotJB protein DUF4834 PF16118.5 RUS77786.1 - 0.5 11.4 0.0 0.5 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DNA_pol_phi PF04931.13 RUS77786.1 - 7.9 4.4 49.5 16 3.4 49.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi 7tm_1 PF00001.21 RUS77787.1 - 1e-11 44.7 17.5 1.7e-11 43.9 17.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS77787.1 - 5.4e-09 35.8 2.6 5.4e-09 35.8 2.6 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS77787.1 - 2.5e-08 33.9 12.0 2.5e-08 33.9 12.0 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS77787.1 - 1e-05 25.0 13.3 1e-05 25.0 13.3 1.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx tRNA_U5-meth_tr PF05958.11 RUS77788.1 - 8.2e-21 74.4 0.1 2.2e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 RUS77788.1 - 1.3e-10 41.3 0.1 3.6e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS77788.1 - 1.1e-08 35.6 0.0 5.8e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS77788.1 - 1.7e-07 30.9 0.1 3.6e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RUS77788.1 - 4.6e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 RUS77788.1 - 1.1e-05 25.0 0.1 2.2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 RUS77788.1 - 1.4e-05 24.7 0.4 1.4e-05 24.7 0.4 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 RUS77788.1 - 1.4e-05 24.6 0.3 3.5e-05 23.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 RUS77788.1 - 4.8e-05 23.2 0.4 0.0044 16.8 0.0 2.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 RUS77788.1 - 5.1e-05 23.3 1.4 8.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS77788.1 - 0.0001 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RUS77788.1 - 0.00011 22.0 0.3 0.00045 20.0 0.1 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Ubie_methyltran PF01209.18 RUS77788.1 - 0.00042 19.7 0.1 0.00089 18.7 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 RUS77788.1 - 0.0013 19.3 0.0 0.0039 17.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 RUS77788.1 - 0.0021 17.8 1.1 0.016 15.0 0.1 2.6 2 1 0 2 2 2 1 DNA methylase Methyltransf_18 PF12847.7 RUS77788.1 - 0.019 14.9 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 RUS77788.1 - 0.043 13.5 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 RUS77788.1 - 0.043 13.5 0.9 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Lysine methyltransferase DOT1 PF08123.13 RUS77788.1 - 0.05 13.1 0.5 0.94 9.0 0.1 2.2 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 RUS77788.1 - 0.065 14.0 0.0 0.24 12.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 RUS77788.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AviRa PF11599.8 RUS77788.1 - 0.11 11.9 0.1 0.26 10.7 0.1 1.7 1 0 0 1 1 1 0 RRNA methyltransferase AviRa RRM_1 PF00076.22 RUS77788.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFA PF04828.14 RUS77789.1 - 1.3e-09 38.2 2.2 1.3e-09 38.2 2.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 RUS77789.1 - 0.028 14.6 0.3 0.028 14.6 0.3 2.5 3 0 0 3 3 3 0 Ribosomal protein L37e V-SNARE_C PF12352.8 RUS77790.1 - 1.4e-18 66.9 2.2 1.4e-18 66.9 2.2 3.2 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus WEMBL PF05701.11 RUS77790.1 - 0.00076 18.3 0.9 0.001 17.8 0.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Sec20 PF03908.13 RUS77790.1 - 0.002 18.0 7.3 0.0054 16.6 0.5 2.8 3 0 0 3 3 3 1 Sec20 DUF999 PF06198.11 RUS77790.1 - 0.047 13.7 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) TPR_MLP1_2 PF07926.12 RUS77790.1 - 0.1 12.6 5.1 0.099 12.7 3.1 1.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4404 PF14357.6 RUS77790.1 - 0.15 12.7 4.2 0.26 12.0 0.1 3.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4404) SIR2 PF02146.17 RUS77790.1 - 0.17 11.8 1.8 2.4 8.0 0.1 2.2 1 1 1 2 2 2 0 Sir2 family DUF16 PF01519.16 RUS77790.1 - 0.33 11.4 6.1 3.6 8.1 5.2 2.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 RUS77790.1 - 5.6 7.0 6.0 8.7 6.4 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SpoU_methylase PF00588.19 RUS77791.1 - 9.7e-28 97.1 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RUS77791.1 - 1.2e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Helicase_C PF00271.31 RUS77792.1 - 4.4e-26 91.4 0.2 1.8e-25 89.5 0.1 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RUS77792.1 - 1.2e-19 70.3 0.0 2.6e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.29 RUS77792.1 - 6.1e-17 61.9 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.6 RUS77792.1 - 0.052 13.7 0.2 0.15 12.2 0.2 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain Tim17 PF02466.19 RUS77793.1 - 0.00013 22.3 0.6 0.00022 21.6 0.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SDF PF00375.18 RUS77794.1 - 2.2e-99 333.1 26.4 3e-89 299.8 18.6 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family RskA PF10099.9 RUS77794.1 - 0.66 10.2 4.4 0.46 10.8 1.6 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PAN_4 PF14295.6 RUS77795.1 - 4.7e-07 29.6 19.7 61 3.6 0.0 10.9 11 1 1 12 12 12 0 PAN domain PMG PF05287.12 RUS77795.1 - 2.5e-06 27.7 0.4 0.8 9.7 0.0 3.0 1 1 2 3 3 3 3 PMG protein Terpene_synth PF01397.21 RUS77795.1 - 0.0072 16.0 0.2 23 4.6 0.0 3.7 1 1 2 3 3 3 2 Terpene synthase, N-terminal domain Methyltransf_7 PF03492.15 RUS77795.1 - 0.47 9.6 9.9 99 2.0 0.1 6.1 2 2 4 7 7 7 0 SAM dependent carboxyl methyltransferase PTR2 PF00854.21 RUS77797.1 - 1.9e-51 175.2 2.0 2.7e-51 174.7 2.0 1.2 1 0 0 1 1 1 1 POT family U-box PF04564.15 RUS77798.1 - 4.9e-29 100.3 0.4 8.3e-29 99.6 0.4 1.4 1 0 0 1 1 1 1 U-box domain MLD PF11647.8 RUS77798.1 - 0.11 12.8 0.0 19 5.6 0.0 2.2 2 0 0 2 2 2 0 Membrane Localization Domain Pkinase PF00069.25 RUS77800.1 - 5.9e-50 170.1 0.0 7.9e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77800.1 - 2.4e-33 115.5 0.0 3.2e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS77800.1 - 2.3e-08 33.7 0.0 5.4e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RUS77800.1 - 9.6e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RTBV_P46 PF06216.11 RUS77800.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TPR_6 PF13174.6 RUS77801.1 - 0.19 12.5 0.0 0.55 11.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 RUS77802.1 - 3.6e-29 102.5 0.0 1.2e-28 100.7 0.0 1.8 1 1 0 1 1 1 1 Caspase domain PRP38_assoc PF12871.7 RUS77803.1 - 6.6 7.4 40.1 2.3 8.9 24.5 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2956 PF11169.8 RUS77803.1 - 7 6.9 9.9 1.8 8.8 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Aminotran_3 PF00202.21 RUS77804.1 - 6.1e-75 252.4 0.0 8e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 RUS77804.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF92 PF01940.16 RUS77805.1 - 1.7e-69 233.9 2.9 2.3e-69 233.4 2.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF4199 PF13858.6 RUS77805.1 - 0.056 13.8 2.5 0.15 12.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) HIG_1_N PF04588.13 RUS77807.1 - 1.4e-14 54.0 0.9 2e-14 53.6 0.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region T-box PF00907.22 RUS77808.1 - 1.2e-47 162.6 0.0 1.7e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 T-box SMP_LBD PF17047.5 RUS77809.1 - 4.1 6.8 12.2 7.3 6.0 1.7 3.1 1 1 2 3 3 3 0 Synaptotagmin-like mitochondrial-lipid-binding domain NOA36 PF06524.12 RUS77810.1 - 9.8e-05 21.8 4.7 0.00012 21.5 4.7 1.2 1 0 0 1 1 1 1 NOA36 protein CDC45 PF02724.14 RUS77810.1 - 0.031 12.6 4.3 0.041 12.2 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 RUS77810.1 - 0.081 13.0 1.2 0.1 12.6 1.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 RUS77810.1 - 0.16 11.7 11.6 0.19 11.5 11.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spc7_N PF15402.6 RUS77810.1 - 0.22 9.7 1.0 0.26 9.5 1.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DNA_pol_phi PF04931.13 RUS77810.1 - 1.2 7.1 11.8 1.5 6.8 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 RUS77810.1 - 1.2 8.4 4.7 1.5 8.1 4.3 1.3 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.10 RUS77810.1 - 1.5 9.3 20.5 2.5 8.5 20.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 RUS77810.1 - 1.7 8.5 4.2 2.3 8.0 4.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 RUS77810.1 - 1.7 7.1 3.0 2 6.8 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 RUS77810.1 - 1.8 8.1 4.1 2.3 7.8 4.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sporozoite_P67 PF05642.11 RUS77810.1 - 2 6.4 4.2 2.5 6.1 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 RUS77810.1 - 2.2 6.4 5.1 2.7 6.1 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 RUS77810.1 - 3 6.3 4.6 3.8 6.0 4.6 1.1 1 0 0 1 1 1 0 Utp14 protein Innexin PF00876.18 RUS77811.1 - 1.9e-123 412.2 17.7 2.2e-123 412.0 17.7 1.0 1 0 0 1 1 1 1 Innexin NapE PF06796.11 RUS77811.1 - 2.6 7.7 5.7 6.7 6.3 5.7 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE SNF PF00209.18 RUS77813.1 - 1.7e-57 195.3 21.8 3.9e-49 167.7 4.8 2.9 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family CENP-B_dimeris PF09026.10 RUS77813.1 - 0.00083 19.7 15.1 0.0016 18.8 15.1 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF2955 PF11168.8 RUS77813.1 - 0.0024 17.7 0.4 0.092 12.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2955) Hydrolase_6 PF13344.6 RUS77813.1 - 0.005 16.9 0.3 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2457 PF10446.9 RUS77813.1 - 0.41 9.7 22.4 0.6 9.2 22.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 RUS77813.1 - 0.76 9.5 17.6 1.3 8.7 17.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 RUS77813.1 - 0.93 9.2 4.8 2.3 7.9 4.8 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 RUS77813.1 - 0.97 9.4 7.6 1.7 8.6 7.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 RUS77813.1 - 2.8 8.2 12.5 5.8 7.2 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.12 RUS77813.1 - 4.3 5.4 11.0 6 4.9 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS77813.1 - 5.1 5.3 11.0 7.3 4.7 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 RUS77813.1 - 7.2 6.4 9.9 11 5.8 9.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 RUS77813.1 - 8.4 5.6 23.4 4 6.7 20.8 1.6 2 0 0 2 2 2 0 NOA36 protein DUF1611 PF07755.11 RUS77814.1 - 0.082 12.2 1.7 17 4.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain SNAD2 PF18745.1 RUS77814.1 - 1.6 8.4 4.6 9.4 5.9 0.4 2.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 2 Cdc6_C PF09079.11 RUS77815.1 - 2.6e-15 56.2 1.4 3.4e-15 55.8 0.4 1.8 2 0 0 2 2 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 RUS77815.1 - 2.7e-13 50.5 0.0 5.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS77815.1 - 4.9e-13 49.5 0.2 4.6e-12 46.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS77815.1 - 1.2e-08 35.5 0.7 0.00018 21.9 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain NACHT PF05729.12 RUS77815.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 RUS77815.1 - 2.3e-07 30.8 0.3 4.8e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 RUS77815.1 - 2.5e-06 27.9 0.9 0.0001 22.7 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS77815.1 - 7.9e-05 22.7 0.0 0.00028 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 RUS77815.1 - 0.00013 21.9 0.4 0.0026 17.7 0.4 2.3 1 1 0 1 1 1 1 NTPase Sigma54_activat PF00158.26 RUS77815.1 - 0.00029 20.6 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 RUS77815.1 - 0.00041 20.1 0.0 0.0023 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RUS77815.1 - 0.00067 19.2 0.0 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 RUS77815.1 - 0.00095 19.1 0.2 0.0096 15.9 0.2 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 RUS77815.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RUS77815.1 - 0.0051 16.8 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RUS77815.1 - 0.0053 16.5 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 RUS77815.1 - 0.0077 16.4 1.3 0.51 10.4 0.2 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain cobW PF02492.19 RUS77815.1 - 0.011 15.4 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 RUS77815.1 - 0.012 16.1 0.0 0.033 14.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 RUS77815.1 - 0.014 15.1 1.3 0.54 10.0 0.2 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase KAP_NTPase PF07693.14 RUS77815.1 - 0.032 13.5 0.5 0.62 9.3 0.3 2.1 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 RUS77815.1 - 0.052 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 RUS77815.1 - 0.052 12.7 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 RUS77815.1 - 0.056 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 RUS77815.1 - 0.065 12.4 0.0 2.1 7.5 0.0 2.5 2 1 0 2 2 2 0 TIP49 P-loop domain Rad17 PF03215.15 RUS77815.1 - 0.089 12.7 0.3 0.47 10.3 0.1 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 RUS77815.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 RUS77815.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RFX_DNA_binding PF02257.15 RUS77815.1 - 0.12 13.0 0.0 0.44 11.2 0.0 1.9 2 0 0 2 2 1 0 RFX DNA-binding domain Viral_helicase1 PF01443.18 RUS77815.1 - 0.21 11.3 1.5 0.31 10.7 0.3 1.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase GEMIN8 PF15348.6 RUS77816.1 - 0.097 13.0 0.5 0.18 12.1 0.5 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4464 PF14713.6 RUS77817.1 - 8.8e-75 251.1 0.1 9.9e-75 250.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) NCU-G1 PF15065.6 RUS77818.1 - 8.6e-100 334.2 0.9 1e-99 334.0 0.9 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 SH2 PF00017.24 RUS77821.1 - 6.2e-06 26.2 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain FAM217 PF15344.6 RUS77821.1 - 0.49 10.3 3.9 0.48 10.3 1.7 2.1 2 0 0 2 2 2 0 FAM217 family Pkinase PF00069.25 RUS77822.1 - 7e-61 205.9 0.0 9.5e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77822.1 - 2.9e-34 118.5 0.0 3.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS77822.1 - 2.1e-13 50.2 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS77822.1 - 0.00037 19.4 0.0 0.00081 18.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS77822.1 - 0.0018 18.2 0.2 0.0048 16.9 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS77822.1 - 0.032 13.2 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain LRR_8 PF13855.6 RUS77823.1 - 5.8e-08 32.4 5.8 1.7e-07 30.9 1.9 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS77823.1 - 2.1e-05 24.8 12.1 0.0044 17.4 0.1 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS77823.1 - 0.0016 17.9 0.5 0.0036 16.8 0.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RUS77823.1 - 0.051 14.1 14.9 2.9 8.8 0.7 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat FAM193_C PF15914.5 RUS77824.1 - 2.1e-13 49.8 4.0 7.3e-13 48.1 4.0 2.0 1 0 0 1 1 1 1 FAM193 family C-terminal Beta-lactamase PF00144.24 RUS77825.1 - 4.8e-41 141.1 0.0 6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase AAA_PrkA PF08298.11 RUS77827.1 - 0.072 12.0 0.3 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 PrkA AAA domain ADK PF00406.22 RUS77828.1 - 3e-60 202.7 0.0 3.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RUS77828.1 - 3.4e-24 85.8 0.0 1.1e-23 84.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 RUS77828.1 - 8e-15 54.5 0.1 2.3e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 RUS77828.1 - 7.2e-05 23.0 0.0 0.0002 21.6 0.0 1.7 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 RUS77828.1 - 0.0034 17.1 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Hydin_ADK PF17213.3 RUS77828.1 - 0.0055 17.0 0.2 0.07 13.4 0.0 2.1 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 RUS77828.1 - 0.009 16.6 0.0 0.037 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Sfi1 PF08457.10 RUS77829.1 - 0.0025 16.5 9.0 0.0038 15.8 9.0 1.3 1 1 0 1 1 1 1 Sfi1 spindle body protein DUF565 PF04483.12 RUS77829.1 - 0.048 14.2 0.1 0.06 13.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF565) SLC12 PF03522.15 RUS77830.1 - 3.3e-145 484.4 0.0 3.9e-145 484.2 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 RUS77830.1 - 8e-108 361.1 32.8 9.5e-108 360.8 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease TFIIF_alpha PF05793.12 RUS77830.1 - 1.6 7.3 9.8 2.2 6.8 9.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RasGAP PF00616.19 RUS77832.1 - 9.9e-56 188.7 0.7 5e-55 186.4 0.7 2.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 RUS77832.1 - 3.3e-36 124.5 8.9 3.3e-36 124.5 8.9 3.5 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 RUS77832.1 - 3.1e-24 82.4 5.0 4.3e-05 22.9 0.3 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.31 RUS77832.1 - 1e-16 61.1 0.0 5.4e-16 58.7 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS77832.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain UPF0242 PF06785.11 RUS77833.1 - 0.016 15.3 2.4 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-Q PF13094.6 RUS77833.1 - 0.027 14.7 3.5 0.086 13.0 3.5 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lipoprotein_20 PF13942.6 RUS77833.1 - 0.035 14.0 3.6 0.034 14.1 2.5 1.6 1 1 0 1 1 1 0 YfhG lipoprotein CREPT PF16566.5 RUS77833.1 - 0.054 13.7 5.0 2.8 8.1 0.3 2.9 3 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour FAM76 PF16046.5 RUS77833.1 - 0.37 10.1 7.6 0.1 11.9 1.1 2.1 1 1 0 2 2 2 0 FAM76 protein Fib_alpha PF08702.10 RUS77833.1 - 0.71 10.0 8.0 4.7 7.4 0.3 3.1 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TBCA PF02970.16 RUS77833.1 - 0.9 9.9 5.1 1.1 9.6 0.1 2.8 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF1664 PF07889.12 RUS77833.1 - 1.5 8.8 7.9 50 3.9 0.8 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 RUS77833.1 - 2.1 8.4 8.3 3.4 7.7 1.2 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.23 RUS77834.1 - 5e-62 209.7 0.5 1.2e-61 208.3 0.5 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 RUS77834.1 - 3.1e-32 111.1 0.9 3.1e-32 111.1 0.9 6.1 7 1 1 8 8 8 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 RUS77834.1 - 2.2e-25 88.3 9.1 6.1e-15 54.9 0.1 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 RUS77834.1 - 6.3e-22 77.8 2.8 7.2e-22 77.6 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 RUS77834.1 - 3.5e-19 69.2 0.0 7.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS77834.1 - 3.4e-08 33.7 0.0 3.4e-08 33.7 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 RUS77834.1 - 0.056 13.5 0.2 0.056 13.5 0.2 3.1 2 1 0 2 2 2 0 SLIDE RGM_C PF06534.13 RUS77835.1 - 2.5e-46 157.3 0.0 8e-46 155.7 0.0 1.9 1 1 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 RUS77835.1 - 2.3e-23 83.2 2.9 3.6e-23 82.6 2.9 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus CPG4 PF15481.6 RUS77835.1 - 0.0049 17.5 0.7 0.013 16.1 0.7 1.7 1 0 0 1 1 1 1 Chondroitin proteoglycan 4 DUF3828 PF12883.7 RUS77836.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) ShK PF01549.24 RUS77836.1 - 0.076 13.6 7.2 0.35 11.4 7.2 2.3 1 0 0 1 1 1 0 ShK domain-like Ras PF00071.22 RUS77839.1 - 1.1e-12 47.8 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Ras PF00071.22 RUS77840.1 - 4.4e-18 65.4 0.0 8.4e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS77840.1 - 0.00031 20.9 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS77840.1 - 0.0093 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MULE PF10551.9 RUS77841.1 - 0.024 15.0 0.3 0.053 13.9 0.3 1.6 1 0 0 1 1 1 0 MULE transposase domain FAT PF02259.23 RUS77842.1 - 1.1e-53 182.7 7.1 2.6e-53 181.5 7.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 RUS77842.1 - 1.4e-16 61.1 0.0 4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RUS77842.1 - 6.4e-07 29.1 0.1 2.7e-06 27.1 0.1 2.1 1 0 0 1 1 1 1 FATC domain Sporozoite_P67 PF05642.11 RUS77842.1 - 0.97 7.4 4.9 1.7 6.6 4.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2 PF00096.26 RUS77843.1 - 9.8e-16 57.3 24.3 5e-05 23.5 0.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS77843.1 - 4.8e-13 48.9 26.9 2.3e-07 30.9 2.6 4.5 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS77843.1 - 8.6e-10 38.6 20.7 0.00039 21.0 2.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 RUS77843.1 - 0.00025 21.6 9.8 0.098 13.3 0.3 4.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 RUS77843.1 - 0.0081 16.4 9.8 0.02 15.2 6.7 2.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RUS77843.1 - 0.05 13.6 14.6 0.18 11.9 0.1 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 RUS77843.1 - 0.13 12.7 3.6 0.24 11.9 0.2 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 RUS77843.1 - 0.17 12.3 11.2 0.3 11.5 0.9 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS77843.1 - 0.64 10.4 13.4 9.2 6.7 0.7 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS77843.1 - 0.71 10.2 8.3 0.87 9.9 3.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CHORD PF04968.12 RUS77843.1 - 1.4 9.7 13.0 4.6 8.0 5.0 2.8 1 1 1 2 2 2 0 CHORD zf-C2H2_aberr PF17017.5 RUS77843.1 - 2 8.5 8.1 0.85 9.7 0.6 2.7 1 1 2 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 RUS77843.1 - 8.2 6.7 8.9 37 4.6 8.9 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain VWA PF00092.28 RUS77845.1 - 1.6e-82 275.9 2.7 2.9e-42 144.9 0.2 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS77845.1 - 4.4e-28 98.0 0.5 4.6e-13 49.7 0.0 2.9 3 1 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 RUS77845.1 - 1.6e-07 31.4 0.0 0.0015 18.5 0.0 2.7 2 1 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.9 RUS77845.1 - 1.4e-06 28.6 0.5 0.0014 18.8 0.1 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus Copine PF07002.16 RUS77845.1 - 2.2e-06 27.3 0.0 0.049 13.1 0.0 2.2 2 0 0 2 2 2 2 Copine SOG2 PF10428.9 RUS77845.1 - 0.087 12.0 24.7 0.13 11.5 24.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 RUS77845.1 - 0.64 9.9 11.1 1.8 8.4 10.2 1.9 2 0 0 2 2 2 0 Rifin Mito_carr PF00153.27 RUS77846.1 - 3.6e-13 49.3 0.5 8.2e-08 32.1 0.1 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein LRR_8 PF13855.6 RUS77847.1 - 3.3e-17 62.0 30.6 3.3e-08 33.2 8.7 2.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RUS77847.1 - 2.3e-13 50.1 9.1 4.4e-09 36.5 3.5 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS77847.1 - 4.2e-07 29.6 0.1 6.9e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 RUS77847.1 - 1.7e-06 27.6 7.7 0.3 11.2 0.1 4.0 3 1 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 RUS77847.1 - 0.075 13.6 10.6 12 6.9 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat zf-C3HC4_3 PF13920.6 RUS77848.1 - 1.4e-05 24.8 14.1 1.4e-05 24.8 14.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 RUS77848.1 - 0.79 9.7 26.0 0.8 9.6 1.4 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.9 RUS77848.1 - 5.5 7.0 14.7 6.3 6.8 6.7 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.8 RUS77848.1 - 6.3 6.3 20.6 6.5 6.3 8.6 2.3 2 0 0 2 2 2 0 Spt20 family BTB PF00651.31 RUS77849.1 - 4.6e-21 75.1 0.0 8.5e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS77849.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Na_sulph_symp PF00939.19 RUS77851.1 - 9.6e-72 242.5 25.3 1.2e-40 140.0 7.5 2.7 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS77851.1 - 2.4e-25 89.3 52.6 3.9e-12 46.0 22.1 3.1 2 1 1 3 3 3 3 Citrate transporter Septin PF00735.18 RUS77853.1 - 7.5e-127 422.4 0.0 1e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RUS77853.1 - 1.8e-07 31.2 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS77853.1 - 8.2e-07 29.1 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 RUS77853.1 - 5.3e-05 22.8 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 RUS77853.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 RUS77853.1 - 0.0002 21.0 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS77853.1 - 0.004 17.4 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS77853.1 - 0.0087 16.5 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS77853.1 - 0.0096 16.2 0.0 0.031 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 RUS77853.1 - 0.014 15.5 4.4 0.21 11.6 0.0 3.1 2 2 1 3 3 3 0 Dynamin family ABC_tran PF00005.27 RUS77853.1 - 0.022 15.3 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 RUS77853.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 RUS77853.1 - 0.041 14.4 0.0 0.2 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS77853.1 - 0.052 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1907 PF08925.11 RUS77855.1 - 3.7e-105 351.4 0.0 4.2e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) zf-C3HC4 PF00097.25 RUS77856.1 - 1.7e-06 27.8 8.5 3.6e-06 26.7 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS77856.1 - 3.5e-05 23.6 6.9 0.00011 22.0 6.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS77856.1 - 5.5e-05 22.9 9.3 0.0001 22.1 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS77856.1 - 5.9e-05 23.0 4.9 5.9e-05 23.0 4.9 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 RUS77856.1 - 0.00025 21.3 12.8 0.0006 20.1 12.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS77856.1 - 0.00054 19.9 7.6 0.0019 18.1 7.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RUS77856.1 - 0.0059 16.7 8.6 0.013 15.6 8.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS77856.1 - 0.04 13.8 6.9 0.089 12.7 6.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 RUS77856.1 - 0.63 10.2 5.4 1.7 8.8 5.4 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF4337 PF14235.6 RUS77856.1 - 1.6 8.9 9.6 5.7 7.0 0.5 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4337) BTB PF00651.31 RUS77857.1 - 3.3e-36 123.9 2.0 3.5e-19 69.1 0.0 3.6 3 1 1 4 4 4 2 BTB/POZ domain Kelch_3 PF13415.6 RUS77857.1 - 5.2e-33 112.7 5.7 3.6e-08 33.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS77857.1 - 2.5e-32 110.7 5.6 2.2e-07 30.8 0.0 5.5 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS77857.1 - 1.7e-31 107.5 2.9 3.9e-07 29.6 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 RUS77857.1 - 1.6e-27 94.9 1.7 5.6e-06 26.2 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 RUS77857.1 - 1.6e-26 91.6 4.8 2.6e-07 30.7 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS77857.1 - 1.5e-18 66.0 4.4 2.5e-06 27.3 0.0 5.4 5 0 0 5 5 5 3 Kelch motif BACK PF07707.15 RUS77857.1 - 0.00013 22.0 3.9 0.17 12.0 0.0 2.9 3 0 0 3 3 3 2 BTB And C-terminal Kelch RAG2 PF03089.14 RUS77857.1 - 0.015 14.3 0.1 0.68 8.9 0.0 3.1 4 0 0 4 4 4 0 Recombination activating protein 2 Tti2 PF10521.9 RUS77858.1 - 0.09 12.3 2.6 6.8 6.1 0.1 3.0 1 1 1 3 3 3 0 Tti2 family RabGAP-TBC PF00566.18 RUS77859.1 - 2e-37 129.0 4.9 1.7e-35 122.7 3.7 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 RUS77859.1 - 7.7e-31 106.8 0.1 4.3e-30 104.4 0.0 2.3 3 0 0 3 3 3 1 Rab-binding domain (RBD) RUN PF02759.19 RUS77859.1 - 3.8e-25 88.4 0.1 1.9e-24 86.2 0.1 2.3 1 0 0 1 1 1 1 RUN domain Sec1 PF00995.23 RUS77860.1 - 1.2e-121 407.8 0.1 1.4e-121 407.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family ELYS-bb PF16687.5 RUS77860.1 - 0.032 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin DUF929 PF06053.11 RUS77862.1 - 0.0028 17.0 4.0 0.0032 16.8 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF929) EphA2_TM PF14575.6 RUS77862.1 - 0.0036 18.1 1.3 0.0052 17.6 1.3 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 RUS77862.1 - 0.018 16.0 4.0 0.021 15.8 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4446 PF14584.6 RUS77862.1 - 0.088 12.8 4.7 0.12 12.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Shisa PF13908.6 RUS77862.1 - 0.14 12.4 2.8 0.16 12.2 2.8 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 RUS77862.1 - 0.14 12.0 10.4 0.17 11.8 10.4 1.2 1 0 0 1 1 1 0 TMEM154 protein family Tmemb_9 PF05434.11 RUS77862.1 - 0.16 11.9 4.8 0.2 11.5 4.8 1.3 1 0 0 1 1 1 0 TMEM9 Pox_A21 PF05323.12 RUS77862.1 - 0.25 11.9 6.5 0.38 11.3 6.5 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein DUF515 PF04415.12 RUS77862.1 - 0.32 9.3 7.2 0.35 9.2 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sigma_reg_N PF13800.6 RUS77862.1 - 0.33 11.3 13.1 0.45 10.8 13.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2207 PF09972.9 RUS77862.1 - 0.34 9.6 2.1 0.35 9.6 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.11 RUS77862.1 - 0.36 10.6 8.3 0.45 10.2 8.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF5412 PF17428.2 RUS77862.1 - 0.54 10.1 3.5 0.74 9.7 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5412) YukC PF10140.9 RUS77862.1 - 0.66 8.8 3.3 0.74 8.6 3.3 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Phage_holin_6_1 PF09682.10 RUS77862.1 - 1.2 9.6 8.9 1.8 9.1 8.9 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) OAD_gamma PF04277.13 RUS77862.1 - 1.3 9.6 8.4 2.3 8.9 8.4 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AsmA PF05170.14 RUS77862.1 - 2.5 6.8 5.5 2.7 6.7 5.5 1.2 1 0 0 1 1 1 0 AsmA family VPS9 PF02204.18 RUS77864.1 - 5.6e-29 100.4 0.0 1.2e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 RUS77864.1 - 1.1e-22 80.1 0.3 5.4e-22 77.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 RUS77864.1 - 2.2e-13 49.8 8.8 4.3e-13 48.9 8.8 1.5 1 0 0 1 1 1 1 A20-like zinc finger DUF2935 PF11155.8 RUS77864.1 - 0.029 14.7 0.2 3.4 8.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) FpoO PF10621.9 RUS77864.1 - 0.073 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Peripla_BP_2 PF01497.18 RUS77864.1 - 0.1 12.2 0.8 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Periplasmic binding protein Evf PF18270.1 RUS77864.1 - 0.1 12.0 0.1 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Virulence factor Evf EF-hand_14 PF17959.1 RUS77864.1 - 0.12 12.8 0.2 0.94 9.9 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Protoglobin PF11563.8 RUS77864.1 - 0.13 12.2 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Protoglobin CheZ PF04344.13 RUS77864.1 - 0.15 12.0 2.7 3.5 7.5 0.0 2.8 2 1 1 3 3 3 0 Chemotaxis phosphatase, CheZ DUF445 PF04286.12 RUS77864.1 - 0.15 11.8 1.4 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Tn7_Tnp_TnsA_C PF08721.11 RUS77864.1 - 0.2 12.3 2.1 6.3 7.5 0.0 3.5 4 0 0 4 4 4 0 TnsA endonuclease C terminal Apolipoprotein PF01442.18 RUS77864.1 - 0.65 9.9 4.9 2.2 8.1 0.2 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Cofilin_ADF PF00241.20 RUS77865.1 - 9.9e-26 89.9 0.3 1.2e-25 89.6 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GLE1 PF07817.13 RUS77866.1 - 5.1e-69 232.3 4.9 7.6e-68 228.4 0.0 2.7 2 1 1 3 3 3 1 GLE1-like protein DUF2254 PF10011.9 RUS77866.1 - 0.05 12.4 1.0 0.12 11.2 1.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF572 PF04502.13 RUS77866.1 - 0.49 10.0 28.6 0.75 9.4 28.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) CwsA PF10814.8 RUS77866.1 - 1.9 8.6 6.1 2.3 8.4 3.9 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Pinin_SDK_memA PF04696.13 RUS77866.1 - 2.7 8.1 38.1 3.2 7.8 5.2 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF1647 PF07801.11 RUS77867.1 - 9.8e-12 44.8 0.3 2e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) SIT PF15330.6 RUS77868.1 - 0.51 10.8 2.8 0.73 10.3 0.2 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT CUB PF00431.20 RUS77869.1 - 1.4e-05 25.4 0.0 1.8e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 CUB domain MTP18 PF10558.9 RUS77870.1 - 6e-06 26.3 0.0 4.6e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) MTP18 PF10558.9 RUS77871.1 - 1.3e-18 67.6 0.4 3.6e-08 33.5 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) MRP-63 PF14978.6 RUS77872.1 - 3.5e-15 56.4 0.1 5.5e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 Acyl-CoA_dh_1 PF00441.24 RUS77874.1 - 8.6e-31 107.2 0.2 8.6e-31 107.2 0.2 2.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 RUS77874.1 - 1.5e-17 64.0 0.0 3.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 RUS77874.1 - 2.9e-14 53.0 0.1 5.8e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RUS77874.1 - 3.4e-09 37.1 0.1 3.4e-09 37.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SMP_LBD PF17047.5 RUS77875.1 - 6.7e-46 156.0 0.0 9.8e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 RUS77875.1 - 1.9e-22 79.5 0.0 3.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain Annexin PF00191.20 RUS77876.1 - 1.1e-84 278.5 18.7 5.8e-24 83.9 0.1 5.0 5 0 0 5 5 5 4 Annexin UBA_2 PF08587.11 RUS77876.1 - 0.037 14.1 0.9 0.54 10.4 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Caldesmon PF02029.15 RUS77876.1 - 0.12 11.1 41.7 0.16 10.7 41.7 1.2 1 0 0 1 1 1 0 Caldesmon DUF966 PF06136.13 RUS77876.1 - 5.3 6.7 19.3 6.8 6.3 19.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.7 RUS77876.1 - 9.3 4.2 19.2 11 4.0 19.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPK_catalytic PF04263.16 RUS77877.1 - 1.4e-33 115.5 0.0 1.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 RUS77877.1 - 1.3e-21 76.1 0.1 4.9e-21 74.2 0.0 1.9 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Peptidase_M8 PF01457.16 RUS77878.1 - 2.7e-48 164.9 13.4 8.5e-34 117.1 0.5 3.2 2 1 0 2 2 2 2 Leishmanolysin SprT-like PF10263.9 RUS77878.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 SprT-like family NDUF_B7 PF05676.13 RUS77878.1 - 3.5 7.4 5.5 7.2 6.4 0.4 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ECH_2 PF16113.5 RUS77879.1 - 4.8e-117 391.2 0.0 5.5e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RUS77879.1 - 5e-31 107.9 0.0 5.9e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NRN1 PF15056.6 RUS77880.1 - 0.043 13.9 0.2 0.055 13.6 0.2 1.3 1 0 0 1 1 1 0 Neuritin protein family Form-deh_trans PF09163.11 RUS77880.1 - 0.2 11.4 1.0 0.3 10.9 1.0 1.3 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane GST_N_4 PF17172.4 RUS77882.1 - 8.6e-30 103.4 0.0 1.6e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS77882.1 - 1.9e-17 62.8 0.1 3.4e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS77882.1 - 3.2e-10 39.9 0.0 7.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RUS77882.1 - 6.1e-08 33.0 0.1 1.1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 RUS77882.1 - 8.8e-05 22.7 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS77882.1 - 0.0004 20.5 0.1 0.00084 19.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS77883.1 - 9.8e-30 103.2 0.1 1.9e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS77883.1 - 5.9e-17 61.2 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS77883.1 - 6.3e-09 35.7 0.0 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RUS77883.1 - 2.9e-07 30.8 0.1 5.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 RUS77883.1 - 0.0001 22.4 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS77883.1 - 0.00042 20.5 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Coat_F PF07875.12 RUS77883.1 - 0.02 15.1 0.2 0.07 13.4 0.0 1.9 2 0 0 2 2 2 0 Coat F domain MFS_1 PF07690.16 RUS77884.1 - 6.7e-45 153.5 23.8 2.1e-43 148.6 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Profilin PF00235.19 RUS77885.1 - 3.7e-18 66.0 0.4 4.4e-18 65.8 0.4 1.1 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 RUS77886.1 - 1.9e-17 63.7 0.1 2.1e-17 63.6 0.1 1.0 1 0 0 1 1 1 1 Profilin TPR_19 PF14559.6 RUS77887.1 - 4.4e-52 174.5 63.5 4.7e-07 30.2 0.6 18.1 15 3 2 18 18 18 10 Tetratricopeptide repeat TPR_14 PF13428.6 RUS77887.1 - 4.2e-36 120.5 42.6 0.00027 21.5 0.1 19.5 16 3 4 20 20 18 6 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77887.1 - 8.8e-36 119.1 63.0 0.0002 21.2 0.1 19.4 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_16 PF13432.6 RUS77887.1 - 1.6e-31 108.7 38.7 5e-05 23.9 1.1 13.9 12 2 2 14 14 14 8 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS77887.1 - 6.2e-24 84.0 35.0 0.00011 22.4 2.0 12.3 9 4 2 12 12 12 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RUS77887.1 - 6.3e-22 75.9 29.5 0.00062 19.6 0.0 13.8 15 0 0 15 15 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS77887.1 - 1.2e-21 75.1 42.1 0.00014 21.8 0.0 15.1 15 0 0 15 15 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 RUS77887.1 - 1.9e-19 68.6 60.8 0.0002 21.1 0.2 16.4 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_12 PF13424.6 RUS77887.1 - 7.5e-18 64.6 57.0 0.0004 20.6 0.1 15.0 14 3 1 16 16 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77887.1 - 3.3e-14 52.3 16.1 1.3e-05 24.8 0.0 10.1 11 0 0 11 11 10 3 TPR repeat TPR_17 PF13431.6 RUS77887.1 - 1.7e-13 49.9 15.9 0.065 13.6 0.1 11.1 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 RUS77887.1 - 2e-11 44.0 40.1 0.00037 20.3 0.3 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 RUS77887.1 - 2.3e-11 43.5 51.9 0.3 11.8 0.0 17.1 20 0 0 20 20 16 4 Tetratricopeptide repeat TPR_4 PF07721.14 RUS77887.1 - 5.3e-09 35.8 8.3 8.4 7.3 0.0 10.3 10 0 0 10 10 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS77887.1 - 2e-08 34.1 11.1 4.5e-05 23.4 0.0 7.4 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 RUS77887.1 - 2.8e-07 30.6 18.5 0.019 15.1 0.0 8.6 8 2 2 10 10 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 RUS77887.1 - 2.3e-05 23.7 43.6 0.34 10.1 0.9 8.4 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_20 PF14561.6 RUS77887.1 - 0.00016 21.9 33.2 1.2 9.6 0.9 11.1 11 2 2 13 13 11 2 Tetratricopeptide repeat HemY_N PF07219.13 RUS77887.1 - 0.0069 16.6 2.8 16 5.8 0.1 5.2 4 1 1 5 5 4 0 HemY protein N-terminus PPR PF01535.20 RUS77887.1 - 0.054 13.8 15.3 14 6.2 0.1 8.6 9 0 0 9 9 9 0 PPR repeat SRP_TPR_like PF17004.5 RUS77887.1 - 0.094 12.7 15.7 0.43 10.6 1.1 5.9 6 0 0 6 6 6 0 Putative TPR-like repeat PknG_TPR PF16918.5 RUS77887.1 - 0.13 11.0 0.0 0.13 11.0 0.0 5.6 6 2 1 8 8 8 0 Protein kinase G tetratricopeptide repeat SPOB_a PF14689.6 RUS77887.1 - 0.28 10.9 15.5 1.3 8.8 0.0 7.0 8 0 0 8 8 8 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_10 PF13374.6 RUS77887.1 - 0.3 11.0 39.1 14 5.7 0.2 12.8 16 0 0 16 16 14 0 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.16 RUS77887.1 - 0.98 9.8 3.3 1 9.7 0.4 2.6 3 0 0 3 3 1 0 RNA polymerase Rpb4 Bax1-I PF01027.20 RUS77888.1 - 2.4e-49 168.0 27.0 2.7e-49 167.8 27.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 RUS77888.1 - 1.5e-05 24.7 17.4 2.2e-05 24.1 17.4 1.3 1 0 0 1 1 1 1 Bax inhibitor 1 like 7TMR-DISM_7TM PF07695.11 RUS77888.1 - 0.016 15.1 3.9 0.016 15.1 3.9 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2518 PF10726.9 RUS77888.1 - 0.11 12.2 7.9 0.081 12.6 5.5 2.0 2 0 0 2 2 2 0 Protein of function (DUF2518) FixP_N PF14715.6 RUS77888.1 - 1.2 8.9 8.2 0.14 11.9 1.1 2.9 2 1 1 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SPC25 PF06703.11 RUS77888.1 - 1.9 8.2 12.1 0.74 9.6 0.6 2.6 1 1 2 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1772 PF08592.11 RUS77888.1 - 3.8 7.8 11.9 0.25 11.7 0.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) SNARE PF05739.19 RUS77888.1 - 4.4 7.4 6.5 0.99 9.4 0.2 2.7 2 0 0 2 2 2 0 SNARE domain YfhO PF09586.10 RUS77888.1 - 7.7 4.6 15.6 3.8 5.6 13.0 1.7 1 1 0 1 1 1 0 Bacterial membrane protein YfhO Sulfotransfer_1 PF00685.27 RUS77889.1 - 2.3e-07 30.6 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS77889.1 - 5.9e-07 30.1 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family zf-C4 PF00105.18 RUS77890.1 - 1.1e-23 83.5 14.0 2.5e-23 82.3 14.0 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS77890.1 - 5.5e-12 45.7 1.3 1.5e-11 44.3 0.2 2.1 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF3899 PF13038.6 RUS77890.1 - 0.27 11.8 0.7 8 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) BUD22 PF09073.10 RUS77891.1 - 0.00096 18.6 5.1 0.0015 18.0 5.1 1.3 1 0 0 1 1 1 1 BUD22 DUF2615 PF11027.8 RUS77891.1 - 0.0032 17.6 0.3 0.0032 17.6 0.3 6.2 1 1 5 6 6 6 1 Protein of unknown function (DUF2615) DUF1218 PF06749.12 RUS77891.1 - 0.014 15.9 0.2 0.014 15.9 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF2428 PF10350.9 RUS77891.1 - 0.021 14.1 1.1 0.039 13.2 0.4 1.8 2 1 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Conotoxin PF02950.17 RUS77891.1 - 0.18 12.8 0.1 0.18 12.8 0.1 7.3 4 3 1 5 5 5 0 Conotoxin TctB PF07331.11 RUS77891.1 - 0.9 9.8 31.6 1.4e+02 2.7 5.8 3.4 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Med15 PF09606.10 RUS77893.1 - 1.3e-53 182.9 64.1 9.2e-39 133.8 19.4 2.5 1 1 1 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 RUS77893.1 - 0.009 16.0 3.5 0.024 14.6 3.5 1.7 1 0 0 1 1 1 1 KIX domain Lipoprotein_10 PF03202.13 RUS77893.1 - 1.2 9.6 4.3 2.1 8.8 0.2 2.5 2 1 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region HSCB_C PF07743.13 RUS77893.1 - 1.4 9.5 4.6 0.37 11.3 1.0 1.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Il2rg PF15874.5 RUS77894.1 - 2.4e-06 27.7 0.2 3e-05 24.2 0.1 2.1 1 1 1 2 2 2 1 Putative Interleukin 2 receptor, gamma chain EphA2_TM PF14575.6 RUS77895.1 - 0.059 14.3 0.3 0.11 13.4 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Furin-like PF00757.20 RUS77895.1 - 0.48 10.3 31.2 3 7.7 6.6 2.9 1 1 2 3 3 3 0 Furin-like cysteine rich region SKG6 PF08693.10 RUS77895.1 - 6.7 6.2 11.1 11 5.5 11.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fer4 PF00037.27 RUS77898.1 - 0.7 9.8 0.2 0.7 9.8 0.2 6.9 10 1 0 10 10 10 0 4Fe-4S binding domain Fer4_6 PF12837.7 RUS77898.1 - 1.1 9.5 0.1 1.1 9.5 0.1 7.1 4 3 1 5 5 5 0 4Fe-4S binding domain Laminin_EGF PF00053.24 RUS77899.1 - 3.4e-06 27.1 72.7 0.29 11.3 8.8 5.4 1 1 4 5 5 5 4 Laminin EGF domain Transmemb_17 PF09799.9 RUS77900.1 - 1.6e-27 96.2 14.5 2.2e-27 95.7 14.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein MFS_1 PF07690.16 RUS77900.1 - 0.005 15.8 1.3 0.0062 15.5 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily YfhO PF09586.10 RUS77900.1 - 0.015 13.6 7.2 0.019 13.3 7.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CENP-M PF11111.8 RUS77901.1 - 7.8e-15 54.5 0.0 9.8e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 Centromere protein M (CENP-M) DUF1704 PF08014.11 RUS77904.1 - 0.0076 15.3 0.2 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) DUF932 PF06067.11 RUS77904.1 - 0.038 13.7 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DDE_Tnp_1_7 PF13843.6 RUS77905.1 - 4.9e-10 39.2 0.0 7.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 RNase_P_Rpp14 PF01900.19 RUS77908.1 - 3.4e-26 91.5 0.1 5.3e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family CBM_14 PF01607.24 RUS77909.1 - 6.9e-23 80.6 65.3 0.0011 19.1 1.7 10.6 2 1 9 11 11 11 9 Chitin binding Peritrophin-A domain TACI-CRD2 PF09305.10 RUS77910.1 - 0.0006 19.8 17.8 0.16 12.0 0.7 4.0 2 1 2 4 4 4 3 TACI, cysteine-rich domain DUF4215 PF13948.6 RUS77910.1 - 0.051 14.0 6.6 0.051 14.0 6.6 4.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4215) CBM_14 PF01607.24 RUS77910.1 - 0.063 13.5 25.2 0.35 11.1 0.5 4.5 1 1 3 4 4 4 0 Chitin binding Peritrophin-A domain Carb_anhydrase PF00194.21 RUS77911.1 - 5e-52 176.9 0.0 7.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PD40 PF07676.12 RUS77912.1 - 1.1 9.3 9.8 11 6.2 0.1 4.3 4 1 1 5 5 5 0 WD40-like Beta Propeller Repeat DUF4160 PF13711.6 RUS77912.1 - 1.4 9.2 7.5 48 4.4 0.2 4.9 3 2 4 7 7 7 0 Domain of unknown function (DUF4160) Tubulin PF00091.25 RUS77913.1 - 2.6e-68 230.1 0.0 3.5e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS77913.1 - 6.9e-52 174.9 0.0 1.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS77913.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RT_RNaseH_2 PF17919.1 RUS77915.1 - 5.4e-33 113.0 0.2 1.3e-32 111.8 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS77915.1 - 5.1e-28 97.4 0.0 9.6e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS77915.1 - 3e-23 82.5 0.0 5e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 RUS77916.1 - 0.06 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Fibrinogen_C PF00147.18 RUS77917.1 - 3e-24 86.1 10.5 5.1e-23 82.0 10.5 2.0 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Ig_3 PF13927.6 RUS77919.1 - 5.8e-33 113.3 2.3 1.1e-07 32.4 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 RUS77919.1 - 1e-23 83.5 0.7 1.1e-07 32.1 0.2 5.9 6 0 0 6 6 6 4 Immunoglobulin domain I-set PF07679.16 RUS77919.1 - 4.7e-19 68.2 0.0 8.7e-07 28.9 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 RUS77919.1 - 1.6e-16 60.2 0.0 0.0023 18.1 0.0 6.4 6 1 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 RUS77919.1 - 8.7e-11 42.0 0.0 8.7e-09 35.5 0.0 3.6 4 1 0 4 4 4 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS77919.1 - 5.7e-06 26.3 1.5 0.0068 16.4 0.0 4.8 4 1 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS77919.1 - 0.11 12.9 0.0 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain SelP_N PF04592.14 RUS77919.1 - 6.4 6.1 16.2 10 5.5 16.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mid2 PF04478.12 RUS77920.1 - 0.00016 21.6 0.4 0.00031 20.6 0.4 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor I-set PF07679.16 RUS77920.1 - 0.0024 17.9 0.1 0.004 17.2 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain EphA2_TM PF14575.6 RUS77920.1 - 0.063 14.2 2.7 0.24 12.3 2.7 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.10 RUS77920.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Ig_3 PF13927.6 RUS77920.1 - 0.15 12.7 0.6 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin domain PALP PF00291.25 RUS77921.1 - 4.7e-37 128.0 0.1 2.4e-24 86.3 0.0 3.1 1 1 2 3 3 3 3 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RUS77921.1 - 0.092 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 CBS domain Ras PF00071.22 RUS77922.1 - 2.2e-43 147.7 0.0 1.7e-34 118.8 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RUS77922.1 - 2.6e-18 66.4 0.0 3.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS77922.1 - 8.9e-08 31.8 0.2 2.2e-05 24.0 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 RUS77922.1 - 0.0067 16.2 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain Gtr1_RagA PF04670.12 RUS77922.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS77922.1 - 0.026 14.6 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS77922.1 - 0.069 12.7 0.5 5.8 6.4 0.1 2.7 1 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Fibrinogen_C PF00147.18 RUS77923.1 - 3.5e-26 92.4 6.2 4.2e-26 92.1 6.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2347 PF09804.9 RUS77924.1 - 3.6e-05 23.5 25.5 0.74 9.3 0.5 5.8 1 1 4 5 5 5 5 Uncharacterized conserved protein (DUF2347) Guanylate_cyc PF00211.20 RUS77925.1 - 1.4e-30 106.3 0.0 2.9e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 RUS77925.1 - 5.5e-30 105.5 0.1 5.5e-30 105.5 0.1 2.8 3 1 0 3 3 3 1 Nitrate and nitrite sensing DNA_pol_phi PF04931.13 RUS77925.1 - 0.00093 17.4 43.2 0.00093 17.4 43.2 3.7 3 1 1 4 4 4 1 DNA polymerase phi Phasin PF05597.11 RUS77925.1 - 4.6 7.3 18.7 0.54 10.3 2.0 4.1 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 RUS77926.1 - 0.044 13.8 0.5 2.8 8.0 0.5 2.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RTP PF02334.16 RUS77926.1 - 0.15 12.7 12.8 22 5.7 0.8 4.8 1 1 5 6 6 6 0 Replication terminator protein DUF5409 PF17421.2 RUS77926.1 - 3.4 8.4 14.0 43 4.9 0.9 4.3 1 1 3 4 4 4 0 Family of unknown function (DUF5409) DXP_redisom_C PF08436.12 RUS77927.1 - 0.16 12.1 17.8 35 4.6 2.7 7.2 1 1 5 6 6 6 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DUF3528 PF12045.8 RUS77927.1 - 7.2 7.2 8.6 8.4e+02 0.5 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3528) Sulfotransfer_1 PF00685.27 RUS77928.1 - 7.9e-21 74.7 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS77928.1 - 1.8e-07 31.8 0.0 0.0028 18.1 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS77928.1 - 0.00071 19.6 0.6 0.0013 18.7 0.5 1.7 1 1 0 1 1 1 1 Sulfotransferase family Pkinase_fungal PF17667.1 RUS77928.1 - 0.049 12.4 0.4 0.082 11.7 0.1 1.4 2 0 0 2 2 2 0 Fungal protein kinase IQ PF00612.27 RUS77929.1 - 1.2e-05 24.7 0.1 3.5e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif IL23 PF16649.5 RUS77929.1 - 0.071 13.2 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Interleukin 23 subunit alpha Molybdopterin_N PF18364.1 RUS77930.1 - 0.069 13.2 48.5 1.8 8.7 0.6 7.8 8 0 0 8 8 8 0 Molybdopterin oxidoreductase N-terminal domain IGFBP PF00219.18 RUS77931.1 - 1.5e-06 28.8 21.2 2.3e-06 28.1 21.2 1.3 1 0 0 1 1 1 1 Insulin-like growth factor binding protein 7TM_GPCR_Srsx PF10320.9 RUS77933.1 - 0.0003 20.2 1.3 0.00048 19.6 1.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS77933.1 - 0.0019 17.6 2.2 0.0073 15.7 2.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS77933.1 - 0.003 16.9 3.5 0.021 14.1 0.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Claudin_3 PF06653.11 RUS77933.1 - 0.0042 17.0 0.2 0.0042 17.0 0.2 2.1 2 1 0 2 2 2 1 Tight junction protein, Claudin-like PknH_C PF14032.6 RUS77933.1 - 0.0056 16.6 0.1 0.0068 16.3 0.1 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain Orf78 PF06024.12 RUS77933.1 - 0.045 14.0 0.1 0.63 10.4 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) ECF_trnsprt PF12822.7 RUS77933.1 - 0.049 13.7 0.6 1.1 9.3 0.1 2.4 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Aminotran_1_2 PF00155.21 RUS77934.1 - 2.3e-70 237.6 0.0 2.7e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RUS77934.1 - 0.00043 19.4 0.0 0.00081 18.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RUS77934.1 - 0.0038 15.8 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HATPase_c_5 PF14501.6 RUS77934.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 GHKL domain Beta_elim_lyase PF01212.21 RUS77934.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RUS77934.1 - 0.12 11.7 0.0 0.65 9.2 0.0 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Oxysterol_BP PF01237.18 RUS77935.1 - 5.7e-78 262.4 4.3 5e-75 252.7 0.1 3.2 2 1 0 2 2 2 2 Oxysterol-binding protein PH PF00169.29 RUS77935.1 - 1.4e-10 41.6 0.0 9.9e-10 38.9 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RUS77935.1 - 8e-09 35.7 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 RUS77935.1 - 3.3e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 RUS77935.1 - 0.0024 17.7 1.8 0.016 15.0 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Ets PF00178.22 RUS77936.1 - 3e-30 104.5 0.7 5.6e-30 103.6 0.7 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 RUS77936.1 - 1.4e-08 34.5 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Nup160 PF11715.8 RUS77937.1 - 1.6e-62 211.9 0.0 2.2e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FAM110_C PF14160.6 RUS77937.1 - 0.14 13.3 0.0 0.36 11.9 0.0 1.7 1 0 0 1 1 1 0 Centrosome-associated C terminus DUF4044 PF13253.6 RUS77938.1 - 0.48 10.0 2.1 0.88 9.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Nup54 PF13874.6 RUS77939.1 - 0.00011 22.3 0.6 0.0002 21.5 0.6 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Laminin_II PF06009.12 RUS77939.1 - 0.00025 21.1 5.5 0.034 14.2 0.2 2.4 1 1 1 2 2 2 2 Laminin Domain II NPV_P10 PF05531.12 RUS77939.1 - 0.0077 16.7 4.9 1.9 9.0 0.6 3.3 1 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.20 RUS77939.1 - 0.017 14.5 5.3 0.017 14.5 3.6 1.7 1 1 0 1 1 1 0 Tropomyosin IFT57 PF10498.9 RUS77939.1 - 0.024 13.6 6.1 0.043 12.8 1.8 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HigB-like_toxin PF05015.13 RUS77939.1 - 0.033 14.6 0.4 0.1 13.0 0.2 1.9 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB GAS PF13851.6 RUS77939.1 - 0.047 13.0 3.6 0.054 12.8 2.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 RUS77939.1 - 0.06 13.6 1.5 58 4.0 0.2 3.3 3 0 0 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 RUS77939.1 - 0.062 13.4 5.2 0.82 9.7 1.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TssO PF17561.2 RUS77939.1 - 0.069 13.3 1.4 2.6 8.1 0.6 2.3 1 1 1 2 2 2 0 Type VI secretion system, TssO Jnk-SapK_ap_N PF09744.9 RUS77939.1 - 0.087 13.0 3.6 0.11 12.8 2.5 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 RUS77939.1 - 0.093 13.0 1.9 0.27 11.5 1.3 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 RUS77939.1 - 0.16 12.1 5.6 0.27 11.4 5.2 1.5 1 1 0 1 1 1 0 Tropomyosin like Snapin_Pallidin PF14712.6 RUS77939.1 - 0.23 11.9 1.6 7 7.1 0.5 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 RUS77939.1 - 0.28 11.2 4.1 5.6 7.0 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAT_alpha PF01017.20 RUS77939.1 - 0.29 11.0 3.2 0.57 10.1 3.2 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain Spc7 PF08317.11 RUS77939.1 - 0.41 9.5 4.9 1.4 7.8 0.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 RUS77939.1 - 0.68 10.4 5.2 6.2 7.3 0.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RUS77939.1 - 4.9 7.5 5.5 11 6.4 0.8 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) I-set PF07679.16 RUS77940.1 - 8.1e-30 102.7 0.0 2e-10 40.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77940.1 - 1.3e-28 99.4 0.5 2.5e-10 40.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS77940.1 - 2.6e-18 66.0 0.1 1.5e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS77940.1 - 1.2e-17 64.1 0.9 1.1e-08 35.2 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS77940.1 - 1.4e-16 60.6 0.1 1.1e-05 25.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain C1-set PF07654.15 RUS77940.1 - 0.0057 17.0 0.6 3.5 8.1 0.0 3.5 2 1 2 4 4 4 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 RUS77940.1 - 0.0093 15.5 0.0 0.15 11.6 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS77940.1 - 0.0098 15.9 0.3 3.3 7.8 0.0 3.6 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS77940.1 - 0.057 13.5 0.1 0.31 11.1 0.0 2.4 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Rif1_N PF12231.8 RUS77941.1 - 3.7e-05 22.9 5.3 4.2e-05 22.7 5.3 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DUF3384 PF11864.8 RUS77941.1 - 0.0049 15.8 4.5 0.0065 15.4 4.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Proteasom_PSMB PF10508.9 RUS77941.1 - 0.034 12.7 2.1 0.035 12.6 2.1 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit L27_1 PF09058.10 RUS77941.1 - 0.038 14.0 3.2 0.083 12.9 0.1 2.7 2 2 0 2 2 2 0 L27_1 MIEAP PF16026.5 RUS77941.1 - 0.18 12.0 2.4 0.23 11.6 2.4 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein Rif1_N PF12231.8 RUS77942.1 - 1.7e-17 63.5 3.0 2.7e-17 62.8 3.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Peptidase_S8 PF00082.22 RUS77945.1 - 8.2e-50 169.7 5.2 1.6e-49 168.8 5.2 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RUS77945.1 - 7e-28 96.5 0.1 1.8e-27 95.1 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 RUS77945.1 - 2e-21 76.5 2.4 2e-21 76.5 2.4 3.4 3 1 1 4 4 4 1 Peptidase S8 pro-domain VSP PF03302.13 RUS77945.1 - 0.0044 15.9 13.1 0.044 12.6 4.0 2.3 2 0 0 2 2 2 2 Giardia variant-specific surface protein Furin-like_2 PF15913.5 RUS77945.1 - 0.0098 16.0 0.2 0.0098 16.0 0.2 2.3 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich DUF3679 PF12438.8 RUS77945.1 - 0.047 13.4 0.3 0.1 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3679) Ank_2 PF12796.7 RUS77946.1 - 9.7e-36 122.2 1.5 1.3e-12 48.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS77946.1 - 1.7e-30 105.0 5.3 1.5e-10 41.4 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS77946.1 - 2.5e-27 94.1 4.2 5.6e-05 23.4 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS77946.1 - 3.3e-27 94.2 1.1 6.7e-10 39.0 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS77946.1 - 1.2e-25 86.8 1.6 0.00096 19.4 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Rootletin PF15035.6 RUS77946.1 - 0.0084 16.1 19.6 0.0084 16.1 19.6 7.2 3 2 2 5 5 5 1 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 RUS77946.1 - 0.032 14.5 83.7 0.048 13.9 8.1 11.8 10 2 2 12 12 12 0 Homeobox associated leucine zipper RVT_N PF13655.6 RUS77946.1 - 0.14 12.4 1.5 0.94 9.8 0.1 3.2 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase WD40_alt PF14077.6 RUS77946.1 - 0.93 9.4 4.3 21 5.0 0.1 4.6 4 0 0 4 4 4 0 Alternative WD40 repeat motif bZIP_1 PF00170.21 RUS77946.1 - 0.97 9.6 86.1 0.17 12.0 0.4 11.6 10 1 1 11 11 11 0 bZIP transcription factor LRR_8 PF13855.6 RUS77947.1 - 2.1e-24 85.0 9.9 1.1e-13 50.7 4.3 2.6 2 0 0 2 2 2 2 Leucine rich repeat TIR_2 PF13676.6 RUS77947.1 - 2.7e-18 66.7 0.0 4.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS77947.1 - 3.5e-15 56.2 0.0 5.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 RUS77947.1 - 9.6e-10 38.6 13.7 0.00011 22.5 2.5 3.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS77947.1 - 7e-08 32.5 0.7 2.2e-07 30.9 0.2 2.0 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS77947.1 - 9.4e-05 22.0 1.1 0.0014 18.2 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RUS77947.1 - 0.00018 21.6 11.3 19 6.3 0.0 5.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS77947.1 - 0.1 12.7 15.4 0.92 9.7 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeat DUF4207 PF13904.6 RUS77948.1 - 2.9e-29 102.5 49.4 3.9e-29 102.1 49.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Ank PF00023.30 RUS77949.1 - 0.0006 20.1 0.0 0.0027 18.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS77949.1 - 0.011 16.3 0.0 0.08 13.5 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS77949.1 - 0.014 16.0 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS77949.1 - 0.093 13.3 0.0 0.9 10.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 RUS77950.1 - 1.1e-05 25.5 0.2 0.015 15.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS77950.1 - 1.2e-05 25.8 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS77950.1 - 0.0002 21.5 0.1 2.2 9.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS77950.1 - 0.00077 20.0 0.0 0.004 17.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS77950.1 - 0.0028 18.0 0.0 3.5 8.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Dpy-30 PF05186.13 RUS77951.1 - 4.2e-13 48.7 0.1 8.2e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif Ank_2 PF12796.7 RUS77951.1 - 6.1e-09 36.3 0.0 4e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS77951.1 - 1.8e-05 24.9 1.1 0.0091 16.3 0.5 3.4 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS77951.1 - 0.00015 22.2 1.4 0.091 13.4 0.8 4.1 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS77951.1 - 0.00035 20.9 0.1 0.019 15.4 0.0 3.3 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RUS77951.1 - 0.05 14.2 0.3 43 5.2 0.0 3.7 3 1 0 3 3 3 0 Ankyrin repeat SRP14 PF02290.15 RUS77951.1 - 0.13 12.7 0.8 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Ndc1_Nup PF09531.10 RUS77951.1 - 3.7 6.1 4.5 3.1 6.4 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 RUS77951.1 - 9.7 4.0 7.7 13 3.5 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DHC_N2 PF08393.13 RUS77952.1 - 8.1e-76 255.7 1.6 8.1e-76 255.7 1.6 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RUS77952.1 - 6.2e-63 212.7 9.5 7.7e-34 117.1 0.0 5.0 5 0 0 5 5 5 3 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RUS77952.1 - 1.9e-44 151.9 0.4 5.7e-42 143.8 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RUS77952.1 - 6.9e-30 103.9 0.2 6.6e-22 77.9 0.0 3.8 4 0 0 4 4 3 3 P-loop containing dynein motor region AAA_5 PF07728.14 RUS77952.1 - 9.6e-16 58.0 0.1 0.0047 16.9 0.1 4.8 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS77952.1 - 8.3e-12 45.7 0.1 0.028 14.8 0.0 5.7 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 RUS77952.1 - 3.2e-11 43.4 2.5 9.5e-11 41.9 0.1 3.2 3 1 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RUS77952.1 - 3.4e-10 40.6 0.4 0.051 14.0 0.0 5.1 5 0 0 5 5 3 3 AAA ATPase domain AAA_lid_1 PF17857.1 RUS77952.1 - 5.4e-08 33.0 0.1 0.011 15.9 0.0 2.9 1 1 1 2 2 2 2 AAA+ lid domain AAA_18 PF13238.6 RUS77952.1 - 2.2e-07 31.5 0.2 1.6 9.3 0.0 4.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RUS77952.1 - 2.3e-07 31.2 1.1 0.34 11.2 0.0 4.6 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 RUS77952.1 - 1e-05 25.9 1.1 2.5 8.4 0.1 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RUS77952.1 - 3.8e-05 24.0 0.0 9.6 6.6 0.0 4.1 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.6 RUS77952.1 - 5.8e-05 23.0 0.6 2.3 7.9 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 RUS77952.1 - 6.3e-05 22.8 0.1 3.1 7.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 RUS77952.1 - 0.00033 20.6 3.4 4.7 7.2 0.1 4.3 4 1 1 5 5 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RUS77952.1 - 0.00038 20.6 1.5 3.9 7.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 RUS77952.1 - 0.00048 19.5 0.6 0.049 12.9 0.0 3.2 4 0 0 4 4 3 1 Zeta toxin Mg_chelatase PF01078.21 RUS77952.1 - 0.00068 19.1 0.7 5.5 6.3 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 RUS77952.1 - 0.00078 19.7 1.4 13 6.0 0.1 4.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 RUS77952.1 - 0.00093 19.2 1.9 0.79 9.6 0.1 3.7 3 1 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 RUS77952.1 - 0.0011 19.5 1.1 5.4 7.5 0.1 4.2 3 0 0 3 3 3 0 ABC transporter AAA_25 PF13481.6 RUS77952.1 - 0.0033 17.0 0.5 0.31 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 RUS77952.1 - 0.004 17.1 1.7 3.3 7.6 0.0 4.1 4 0 0 4 4 4 1 RsgA GTPase AAA_24 PF13479.6 RUS77952.1 - 0.0054 16.5 0.3 22 4.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 RUS77952.1 - 0.0064 16.6 0.0 7.5 6.7 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 RUS77952.1 - 0.01 15.6 0.5 6.8 6.4 0.0 3.0 4 0 0 4 4 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 RUS77952.1 - 0.011 15.1 0.1 2 7.7 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 RUS77952.1 - 0.016 15.0 0.0 18 5.0 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein RuvB_N PF05496.12 RUS77952.1 - 0.021 14.5 0.1 1.8 8.3 0.1 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 RUS77952.1 - 0.026 14.4 0.0 17 5.3 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 RUS77952.1 - 0.027 13.9 0.1 5.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 RUS77952.1 - 0.029 14.6 1.0 5.2 7.3 0.0 3.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 RUS77952.1 - 0.044 12.9 0.0 7 5.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 RUS77952.1 - 0.048 13.6 2.4 10 6.0 0.1 3.3 3 0 0 3 3 2 0 NTPase MMR_HSR1 PF01926.23 RUS77952.1 - 0.084 13.0 0.0 6.3 6.9 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 RUS77952.1 - 0.086 12.6 0.1 13 5.5 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Alpha-2-MRAP_C PF06401.11 RUS77952.1 - 0.13 12.2 10.8 0.1 12.6 2.9 3.1 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain cobW PF02492.19 RUS77952.1 - 0.17 11.4 0.2 25 4.4 0.1 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vac_Fusion PF02346.16 RUS77952.1 - 0.27 10.9 2.2 0.5 10.0 0.0 2.8 3 0 0 3 3 1 0 Chordopoxvirus multifunctional envelope protein A27 Sp38 PF07354.12 RUS77952.1 - 0.34 10.3 1.9 36 3.7 0.1 3.7 3 1 1 4 4 4 0 Zona-pellucida-binding protein (Sp38) Lectin_C PF00059.21 RUS77953.1 - 4.6e-13 49.8 0.4 8.5e-13 49.0 0.4 1.5 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS77953.1 - 0.0004 20.3 0.1 0.0011 18.9 0.1 1.9 1 0 0 1 1 1 1 PAN domain Somatomedin_B PF01033.17 RUS77954.1 - 2.2e-05 24.8 16.8 2.2e-05 24.8 16.8 2.7 2 0 0 2 2 2 1 Somatomedin B domain PTH2 PF01981.16 RUS77956.1 - 2.7e-22 79.2 0.1 3e-22 79.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Robl_LC7 PF03259.17 RUS77956.1 - 0.0054 16.5 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DEAD PF00270.29 RUS77957.1 - 7.8e-50 169.1 0.0 2.3e-49 167.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS77957.1 - 5.1e-23 81.5 0.1 1.7e-21 76.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 RUS77957.1 - 1.1e-15 57.7 12.3 3.8e-15 55.9 12.3 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain PH_17 PF18012.1 RUS77957.1 - 0.12 12.1 0.0 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 PH domain 7tm_1 PF00001.21 RUS77959.1 - 2.1e-21 76.4 9.7 2.4e-21 76.3 9.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS77959.1 - 1.2e-07 31.4 7.2 1.6e-07 31.0 7.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS77959.1 - 0.00038 20.2 9.7 0.00055 19.6 9.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 RUS77959.1 - 0.049 13.4 7.1 0.11 12.3 7.1 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Ldl_recept_a PF00057.18 RUS77960.1 - 1.8e-52 175.2 150.2 3.5e-10 39.9 10.3 10.2 10 1 0 10 10 9 9 Low-density lipoprotein receptor domain class A LRR_8 PF13855.6 RUS77960.1 - 1e-23 82.8 29.2 1.8e-12 46.8 6.5 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS77960.1 - 6.6e-09 35.9 10.2 3.9e-06 27.1 4.1 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS77960.1 - 0.0012 18.4 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat FAM176 PF14851.6 RUS77960.1 - 0.04 13.6 0.9 0.08 12.6 0.9 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 RUS77960.1 - 0.22 11.4 3.7 0.32 10.9 3.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 RUS77960.1 - 0.62 8.5 3.6 0.82 8.1 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 RUS77960.1 - 0.73 9.2 5.1 1 8.7 5.1 1.1 1 0 0 1 1 1 0 SDA1 LRR_1 PF00560.33 RUS77960.1 - 0.94 10.3 11.3 5.4 8.0 0.3 4.6 4 0 0 4 4 3 0 Leucine Rich Repeat PAGK PF15284.6 RUS77960.1 - 0.99 9.4 12.8 19 5.2 0.5 3.8 3 0 0 3 3 3 0 Phage-encoded virulence factor RXT2_N PF08595.11 RUS77960.1 - 4.2 7.4 8.4 6.8 6.7 8.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 RUS77960.1 - 8 6.8 9.8 23 5.3 9.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 RUS77960.1 - 8.9 5.8 6.2 14 5.2 6.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Dicty_REP PF05086.12 RUS77960.1 - 9.3 4.1 6.4 12 3.8 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ldl_recept_a PF00057.18 RUS77961.1 - 1.9e-16 60.0 23.1 2.8e-11 43.4 7.8 2.7 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A adh_short PF00106.25 RUS77963.1 - 0.00011 21.7 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS77963.1 - 0.027 14.0 0.0 0.084 12.4 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Cadherin PF00028.17 RUS77965.1 - 4.3e-106 347.6 2.4 4.6e-16 59.0 0.0 7.1 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS77965.1 - 3e-19 68.6 0.0 2.2e-15 56.2 0.0 4.3 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 RUS77965.1 - 1e-08 35.2 3.9 0.025 14.6 0.1 5.6 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 RUS77965.1 - 0.0018 18.8 2.1 0.0018 18.8 2.1 7.0 7 0 0 7 7 7 2 Bacterial cadherin-like domain RET_CLD1 PF17756.1 RUS77965.1 - 0.0094 16.2 0.0 0.063 13.6 0.0 2.5 3 0 0 3 3 3 1 RET Cadherin like domain 1 SusE PF14292.6 RUS77965.1 - 0.035 14.3 4.1 7.6 6.8 0.1 3.7 4 0 0 4 4 4 0 SusE outer membrane protein DUF4850 PF16142.5 RUS77965.1 - 0.22 11.0 1.6 37 3.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4850) Invasin_D3 PF09134.10 RUS77965.1 - 3 8.2 15.8 1 9.7 0.1 5.5 6 0 0 6 6 6 0 Invasin, domain 3 LRR_8 PF13855.6 RUS77966.1 - 4.9e-21 74.2 20.9 2.7e-11 43.1 1.2 3.9 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RUS77966.1 - 2.9e-10 40.2 20.7 0.0002 21.7 0.2 4.9 4 1 2 6 6 5 4 Leucine Rich repeats (2 copies) I-set PF07679.16 RUS77966.1 - 1.5e-06 28.1 0.1 3.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS77966.1 - 0.00083 19.9 4.2 0.00083 19.9 4.2 3.2 2 1 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 RUS77966.1 - 0.0012 19.1 20.0 0.51 11.1 0.4 6.7 6 1 0 6 6 5 2 Leucine Rich Repeat LRR_9 PF14580.6 RUS77966.1 - 0.0024 17.4 1.8 0.079 12.5 1.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Orf78 PF06024.12 RUS77966.1 - 0.0029 17.9 3.8 0.0059 16.9 3.8 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Consortin_C PF15281.6 RUS77966.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus LRR_6 PF13516.6 RUS77966.1 - 0.027 14.5 16.0 1.4 9.1 0.7 5.4 5 0 0 5 5 5 0 Leucine Rich repeat DUF1180 PF06679.12 RUS77966.1 - 0.064 13.7 0.4 0.064 13.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RUS77966.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF5334 PF17268.2 RUS77966.1 - 0.18 12.1 0.5 0.36 11.2 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5334) HCO3_cotransp PF00955.21 RUS77966.1 - 0.52 9.1 3.4 0.13 11.0 0.4 1.4 2 0 0 2 2 2 0 HCO3- transporter family Peptidase_M56 PF05569.11 RUS77966.1 - 1.1 8.4 2.9 0.41 9.8 0.3 1.5 2 0 0 2 2 2 0 BlaR1 peptidase M56 LRRNT PF01462.18 RUS77966.1 - 4 7.2 6.7 0.58 9.9 1.7 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Shisa PF13908.6 RUS77966.1 - 4.2 7.6 8.4 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF21 PF01595.20 RUS77967.1 - 4.2e-32 111.3 0.1 4.2e-32 111.3 0.1 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RUS77967.1 - 0.00016 22.0 0.5 0.2 12.1 0.1 3.1 2 1 0 2 2 2 2 CBS domain Ala_racemase_N PF01168.20 RUS77968.1 - 3.6e-29 102.0 0.1 4.3e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 RUS77968.1 - 2.6e-23 82.5 0.0 8.7e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain PTH2 PF01981.16 RUS77968.1 - 0.045 14.0 0.0 0.17 12.1 0.0 1.9 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 EphA2_TM PF14575.6 RUS77969.1 - 0.1 13.5 0.0 0.3 12.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mfa1 PF17445.2 RUS77970.1 - 0.71 9.9 3.2 0.55 10.3 0.7 2.2 2 0 0 2 2 2 0 Mating factor A1 Cadherin_C_2 PF16492.5 RUS77970.1 - 3.7 8.4 5.0 3.2 8.6 0.7 2.5 2 1 1 3 3 3 0 Cadherin cytoplasmic C-terminal LRR_6 PF13516.6 RUS77971.1 - 7.4e-13 47.4 0.0 0.00024 20.9 0.0 5.0 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RUS77971.1 - 2.4e-06 27.8 4.1 0.28 11.7 0.2 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.26 RUS77974.1 - 2.2e-26 90.8 61.3 5.6e-06 26.5 0.5 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS77974.1 - 2.2e-21 74.7 60.5 0.00017 22.2 0.7 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS77974.1 - 2e-17 62.7 58.4 1.2e-06 28.7 0.7 7.1 7 0 0 7 7 6 6 Zinc-finger double domain zf-met PF12874.7 RUS77974.1 - 3e-08 33.8 38.3 0.054 13.9 2.2 7.4 7 1 1 8 8 7 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 RUS77974.1 - 7.2e-05 23.5 28.6 0.043 14.6 1.8 4.4 2 1 1 3 3 3 2 zinc-ribbon family Zn-ribbon_8 PF09723.10 RUS77974.1 - 0.00016 21.7 28.5 0.072 13.2 1.5 5.8 4 1 1 5 5 5 3 Zinc ribbon domain zf-C2H2_jaz PF12171.8 RUS77974.1 - 0.00051 20.3 45.1 0.014 15.7 0.1 7.5 7 1 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 RUS77974.1 - 0.00077 19.4 47.8 0.12 12.5 3.6 7.2 2 1 4 6 6 6 3 BED zinc finger GAGA PF09237.11 RUS77974.1 - 0.002 17.9 0.3 0.002 17.9 0.3 3.5 4 1 0 4 4 4 1 GAGA factor zf-Di19 PF05605.12 RUS77974.1 - 0.0031 17.8 40.7 0.016 15.5 3.7 4.9 1 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 RUS77974.1 - 0.0046 17.0 27.0 1.5 8.9 1.8 4.6 1 1 3 4 4 4 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 RUS77974.1 - 0.014 15.4 0.2 0.014 15.4 0.2 4.9 3 3 1 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 RUS77974.1 - 0.023 15.0 43.8 0.87 10.0 11.0 7.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) HTH_ABP1_N PF18107.1 RUS77974.1 - 0.039 13.7 1.6 2 8.2 0.4 2.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Zn_Tnp_IS1595 PF12760.7 RUS77974.1 - 0.05 13.6 1.2 0.05 13.6 1.2 4.9 3 2 1 4 4 3 0 Transposase zinc-ribbon domain zf-C2H2_3rep PF18868.1 RUS77974.1 - 0.062 14.0 31.4 1.3 9.7 15.8 4.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF1610 PF07754.11 RUS77974.1 - 0.16 12.0 3.5 0.54 10.3 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf_UBZ PF18439.1 RUS77974.1 - 0.2 11.3 0.1 0.2 11.3 0.1 7.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 RUS77974.1 - 0.26 11.0 0.2 0.26 11.0 0.2 6.1 7 0 0 7 7 7 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.6 RUS77974.1 - 0.36 10.6 0.2 0.36 10.6 0.2 6.1 6 1 0 6 6 6 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 RUS77974.1 - 0.83 10.0 21.2 39 4.6 3.5 6.6 6 1 1 7 7 7 0 zinc-ribbon DZR PF12773.7 RUS77974.1 - 0.9 9.6 34.8 47 4.1 17.0 4.5 1 1 2 3 3 3 0 Double zinc ribbon zf-LYAR PF08790.11 RUS77974.1 - 1.2 9.1 33.9 0.45 10.5 0.4 6.6 7 0 0 7 7 6 0 LYAR-type C2HC zinc finger TerY_C PF15616.6 RUS77974.1 - 1.5 9.0 13.0 0.11 12.6 1.6 3.0 2 1 1 3 3 3 0 TerY-C metal binding domain DUF2256 PF10013.9 RUS77974.1 - 1.6 8.9 27.7 22 5.3 0.1 7.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) Mut7-C PF01927.16 RUS77974.1 - 2.9 8.0 26.1 0.14 12.3 2.2 4.3 1 1 4 5 5 5 0 Mut7-C RNAse domain PhnA_Zn_Ribbon PF08274.12 RUS77974.1 - 3.4 7.7 0.0 3.4 7.7 0.0 5.2 6 0 0 6 6 5 0 PhnA Zinc-Ribbon Rpr2 PF04032.16 RUS77974.1 - 6 7.2 31.1 0.13 12.6 7.9 3.6 2 2 2 4 4 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain XPA_N PF01286.18 RUS77974.1 - 7.5 6.7 29.3 5.1 7.2 0.1 7.0 7 0 0 7 7 7 0 XPA protein N-terminal zf-CHCC PF10276.9 RUS77974.1 - 10 6.3 14.5 4.8 7.3 0.0 5.1 6 0 0 6 6 5 0 Zinc-finger domain RNase_H PF00075.24 RUS77977.1 - 1.4e-06 28.6 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 RNase H Myc_N PF01056.18 RUS77977.1 - 0.071 13.0 2.9 0.085 12.8 2.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region THOC7 PF05615.13 RUS77978.1 - 1.4e-29 103.0 8.2 1.4e-29 103.0 8.2 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 DUF1664 PF07889.12 RUS77978.1 - 0.42 10.7 6.8 0.63 10.1 5.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC-like PF12805.7 RUS77978.1 - 1.3 8.0 8.2 11 5.1 0.0 2.2 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS MCU PF04678.13 RUS77978.1 - 1.7 8.7 11.1 5.1 7.2 1.8 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter PDGF_N PF04692.13 RUS77978.1 - 1.8 9.4 7.0 0.36 11.6 0.8 2.8 2 2 1 3 3 3 0 Platelet-derived growth factor, N terminal region DUF4407 PF14362.6 RUS77978.1 - 2.7 7.3 12.2 3.8 6.8 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 RUS77978.1 - 3.4 8.2 6.4 48 4.5 6.4 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 RUS77978.1 - 4.1 7.6 18.8 3.7 7.7 5.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1706 PF08020.11 RUS77978.1 - 4.2 7.3 9.4 6.2 6.7 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) Mod_r PF07200.13 RUS77978.1 - 6.4 6.9 20.4 2.9 8.0 3.4 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF883 PF05957.13 RUS77978.1 - 7.1 7.3 9.4 0.77 10.4 2.0 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.15 RUS77978.1 - 8.7 6.2 18.3 5.2 6.9 4.6 2.7 1 1 0 2 2 2 0 Septum formation initiator HAUS5 PF14817.6 RUS77979.1 - 2e-05 23.6 5.8 2.1e-05 23.5 5.8 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 HAUS5 PF14817.6 RUS77980.1 - 1.4e-22 80.3 16.8 1.8e-22 79.9 16.8 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF1045 PF06299.12 RUS77980.1 - 1.1 9.2 6.6 0.94 9.4 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) SARS_X4 PF08779.10 RUS77981.1 - 2.2e-05 24.5 1.0 69 3.7 0.0 5.1 1 1 8 9 9 9 5 SARS coronavirus X4 like LRR_RI_capping PF18779.1 RUS77981.1 - 3.3 7.4 29.2 2.1e+02 1.7 0.1 10.1 11 0 0 11 11 11 0 Capping Ribonuclease inhibitor Leucine Rich Repeat HAUS5 PF14817.6 RUS77982.1 - 1.8e-18 66.7 0.6 2.2e-18 66.4 0.6 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Cep57_CLD_2 PF14197.6 RUS77982.1 - 0.0012 18.9 4.1 0.0022 18.0 4.1 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Atg14 PF10186.9 RUS77982.1 - 0.0046 16.1 2.0 0.006 15.7 2.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2309 PF10070.9 RUS77982.1 - 0.046 12.0 2.1 0.057 11.7 2.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF1843 PF08898.10 RUS77982.1 - 0.22 12.1 1.8 0.45 11.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PVL_ORF50 PF07768.11 RUS77982.1 - 0.28 11.5 2.0 0.47 10.8 2.0 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family TPR_1 PF00515.28 RUS77983.1 - 2.3e-16 58.8 2.4 3.5e-07 29.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS77983.1 - 1e-10 40.9 3.2 1.4e-05 24.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS77983.1 - 3e-06 26.8 0.1 0.039 13.6 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 RUS77983.1 - 4.9e-06 26.6 3.4 1.8e-05 24.8 3.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS77983.1 - 9.4e-05 22.5 2.1 2.8 8.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS77983.1 - 9.7e-05 22.3 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS77983.1 - 0.00024 21.5 1.0 0.44 11.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS77983.1 - 0.00031 21.3 6.1 0.018 15.7 3.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS77983.1 - 0.00045 20.1 2.2 0.38 10.9 0.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS77983.1 - 0.00086 19.8 0.3 0.082 13.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 RUS77983.1 - 0.00096 19.2 0.0 0.77 9.8 0.0 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 RUS77983.1 - 0.0041 17.8 2.7 0.15 12.9 0.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS77983.1 - 0.04 14.2 4.1 0.64 10.4 2.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS77983.1 - 0.12 12.4 0.9 0.27 11.3 0.3 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 RUS77983.1 - 0.2 11.4 6.3 0.32 10.7 0.1 3.0 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Clathrin_propel PF01394.20 RUS77984.1 - 1.1e-05 25.4 0.0 27 5.3 0.0 5.5 1 1 6 7 7 7 2 Clathrin propeller repeat DKCLD PF08068.12 RUS77984.1 - 0.021 14.9 0.8 9.6 6.4 0.0 3.4 1 1 4 5 5 5 0 DKCLD (NUC011) domain DMRL_synthase PF00885.19 RUS77984.1 - 0.12 12.2 0.1 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase MRP-L46 PF11788.8 RUS77985.1 - 3.5e-11 43.9 0.7 6.1e-11 43.1 0.7 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Membralin PF09746.9 RUS77985.1 - 0.028 13.5 0.6 0.036 13.1 0.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein NUDIX PF00293.28 RUS77985.1 - 0.047 13.7 0.4 0.2 11.7 0.4 2.0 1 1 0 1 1 1 0 NUDIX domain Mcm10 PF09332.11 RUS77986.1 - 7.7e-49 167.0 16.8 2.9e-48 165.1 9.5 3.0 2 1 1 3 3 3 3 Mcm10 replication factor zf-primase PF09329.11 RUS77986.1 - 3.3e-15 55.6 3.3 8.4e-15 54.3 3.3 1.8 1 0 0 1 1 1 1 Primase zinc finger OrfB_Zn_ribbon PF07282.11 RUS77986.1 - 4.1 7.4 6.6 20 5.2 6.6 2.2 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF89 PF01937.19 RUS77989.1 - 4.1e-07 29.3 0.2 20 4.0 0.0 6.4 4 2 1 6 6 6 5 Protein of unknown function DUF89 Img2 PF05046.14 RUS77989.1 - 0.1 12.9 13.8 40 4.6 0.0 6.1 6 0 0 6 6 6 0 Mitochondrial large subunit ribosomal protein (Img2) Glutaredoxin2_C PF04399.13 RUS77989.1 - 0.14 12.0 0.3 47 3.8 0.0 3.5 6 0 0 6 6 6 0 Glutaredoxin 2, C terminal domain DSL PF01414.19 RUS77990.1 - 5.2e-08 33.1 2.1 1.6e-07 31.4 2.1 1.8 1 0 0 1 1 1 1 Delta serrate ligand MNNL PF07657.13 RUS77990.1 - 4.3e-05 23.5 0.6 0.00016 21.6 0.6 2.0 1 0 0 1 1 1 1 N terminus of Notch ligand PNRC PF15365.6 RUS77990.1 - 0.00064 19.5 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 Proline-rich nuclear receptor coactivator motif Gas_vesicle_C PF01304.17 RUS77990.1 - 7.1 6.7 11.8 95 3.1 0.1 4.3 4 0 0 4 4 4 0 Gas vesicles protein GVPc repeated domain Fibrinogen_BP PF08017.11 RUS77991.1 - 0.0041 15.6 0.0 0.0041 15.6 0.0 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein zf-CCHC PF00098.23 RUS77994.1 - 1.1 9.4 9.0 3.3e+02 1.6 0.0 5.9 6 0 0 6 6 6 0 Zinc knuckle RPA PF10134.9 RUS77995.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Replication initiator protein A TBK1_CCD1 PF18394.1 RUS77996.1 - 1.6e-18 67.2 2.1 1.9e-18 66.9 2.1 1.1 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Chalcone_3 PF16036.5 RUS77996.1 - 0.11 12.6 0.1 0.47 10.5 0.0 1.8 1 1 1 2 2 2 0 Chalcone isomerase-like Pkinase PF00069.25 RUS77997.1 - 1.2e-27 96.9 0.0 1.6e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS77997.1 - 2.7e-15 56.4 0.0 3.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_ULD PF18396.1 RUS77997.1 - 1.2e-11 44.3 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_fungal PF17667.1 RUS77997.1 - 0.0019 17.1 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TBK1_CCD1 PF18394.1 RUS77997.1 - 0.0023 17.5 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Kinase-like PF14531.6 RUS77997.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ubiquitin PF00240.23 RUS77997.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family YrbL-PhoP_reg PF10707.9 RUS77997.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Hormone_recep PF00104.30 RUS77998.1 - 5.8e-10 39.1 0.0 9.3e-09 35.2 0.0 2.6 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF3439 PF11921.8 RUS77998.1 - 2.4 8.1 6.8 0.5 10.4 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 RUS77998.1 - 4.5 5.1 6.2 6.2 4.7 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UCH PF00443.29 RUS78001.1 - 2e-43 148.8 0.0 2.8e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS78001.1 - 1.1e-25 90.9 0.0 3.1e-25 89.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3011 PF11218.8 RUS78002.1 - 0.073 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) DUF3011 PF11218.8 RUS78003.1 - 7.3e-36 124.0 28.6 5.6e-10 39.5 3.0 7.0 4 3 2 7 7 7 7 Protein of unknown function (DUF3011) Sterol_MT_C PF08498.10 RUS78003.1 - 0.009 16.3 0.7 20 5.6 0.0 4.1 5 0 0 5 5 5 2 Sterol methyltransferase C-terminal IRF-2BP1_2 PF11261.8 RUS78003.1 - 0.039 13.5 4.0 1.5 8.4 0.2 4.4 4 0 0 4 4 4 0 Interferon regulatory factor 2-binding protein zinc finger Sep15_SelM PF08806.11 RUS78003.1 - 0.14 12.3 4.2 13 6.1 0.0 4.6 5 0 0 5 5 5 0 Sep15/SelM redox domain Dioxygenase_C PF00775.21 RUS78003.1 - 0.67 9.4 7.3 77 2.7 0.0 4.8 5 0 0 5 5 5 0 Dioxygenase MG4 PF17789.1 RUS78003.1 - 5 7.3 11.0 1e+02 3.2 0.1 6.1 6 2 0 6 6 6 0 Macroglobulin domain MG4 CarboxypepD_reg PF13620.6 RUS78003.1 - 8.3 6.8 14.6 96 3.4 0.0 6.7 7 0 0 7 7 7 0 Carboxypeptidase regulatory-like domain DUF3011 PF11218.8 RUS78004.1 - 3.9e-11 43.3 0.3 1.2e-10 41.8 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3011) DUF3011 PF11218.8 RUS78005.1 - 1.2e-40 139.7 31.0 1.9e-14 54.1 3.5 6.1 3 1 2 6 6 6 6 Protein of unknown function (DUF3011) Cren7 PF11520.8 RUS78005.1 - 0.1 12.6 6.5 43 4.1 0.0 5.7 6 0 0 6 6 6 0 Chromatin protein Cren7 Enolase_N PF03952.16 RUS78005.1 - 0.22 11.7 1.9 6.3 7.0 0.0 3.6 4 0 0 4 4 4 0 Enolase, N-terminal domain DUF824 PF05688.11 RUS78005.1 - 0.23 11.3 11.2 1 9.2 0.1 5.7 6 0 0 6 6 6 0 Salmonella repeat of unknown function (DUF824) UPF0240 PF06784.11 RUS78006.1 - 8.5e-45 152.9 1.4 1.2e-44 152.5 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Aminotran_1_2 PF00155.21 RUS78007.1 - 8.5e-37 127.2 0.0 1e-36 126.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS78007.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 RUS78007.1 - 0.021 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III p450 PF00067.22 RUS78008.1 - 7.3e-95 318.4 0.0 8.4e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS78009.1 - 3.5e-79 266.7 0.0 3.8e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_1 PF01344.25 RUS78010.1 - 6.3e-80 262.6 13.8 1.4e-15 56.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS78010.1 - 2.9e-47 157.5 4.4 5e-08 33.0 0.0 6.5 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RUS78010.1 - 1.4e-37 126.2 10.1 4.9e-08 32.7 0.3 6.6 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 RUS78010.1 - 2e-33 114.6 0.1 2e-33 114.6 0.1 2.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 RUS78010.1 - 2.8e-28 98.4 0.2 5.7e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 RUS78010.1 - 3e-28 97.6 0.9 9.3e-05 22.4 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS78010.1 - 4.4e-22 77.9 8.7 0.00011 22.3 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS78010.1 - 2.3e-06 27.4 3.6 0.61 10.1 0.0 4.9 5 0 0 5 5 5 2 Kelch motif DUF3342 PF11822.8 RUS78010.1 - 0.0031 17.7 0.1 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Glu_cyclase_2 PF05096.12 RUS78010.1 - 0.036 13.5 0.0 0.93 8.9 0.0 2.2 1 1 0 2 2 2 0 Glutamine cyclotransferase YL1 PF05764.13 RUS78011.1 - 0.0038 17.4 46.0 0.006 16.7 46.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein RNA_pol_3_Rpc31 PF11705.8 RUS78011.1 - 0.0043 17.4 16.1 0.0043 17.4 16.1 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 RUS78011.1 - 0.075 11.3 34.8 0.11 10.8 34.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS78011.1 - 0.09 11.0 32.9 0.12 10.6 32.9 1.1 1 0 0 1 1 1 0 Nop14-like family GRP PF07172.11 RUS78011.1 - 0.85 10.3 9.4 1.9 9.2 0.7 2.4 2 0 0 2 2 2 0 Glycine rich protein family Scs3p PF10261.9 RUS78011.1 - 1.7 8.1 5.0 3.8 7.0 5.0 1.6 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PigN PF04987.14 RUS78011.1 - 4.6 6.0 4.9 8 5.2 4.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Presenilin PF01080.17 RUS78011.1 - 6.4 5.4 15.1 8.9 5.0 15.1 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 RUS78012.1 - 0.0024 17.4 46.0 0.0031 17.0 46.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS78012.1 - 0.075 11.2 47.0 0.11 10.8 47.0 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS78012.1 - 7.1 5.3 15.1 8.4 5.0 15.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S28 PF05577.12 RUS78013.1 - 3.2e-97 326.1 0.9 3.8e-97 325.8 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 RUS78013.1 - 0.00067 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS78013.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 RUS78013.1 - 0.014 14.1 0.6 0.021 13.5 0.1 1.5 2 0 0 2 2 2 0 PS-10 peptidase S37 Peptidase_S9 PF00326.21 RUS78013.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS78013.1 - 0.023 15.3 0.0 0.06 13.9 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 RUS78014.1 - 9.5e-51 171.6 0.0 1.2e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78014.1 - 1.2e-30 106.2 0.0 1.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78014.1 - 2.2e-11 43.5 0.0 4.7e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS78014.1 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS78014.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS78014.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS78014.1 - 0.023 14.6 0.3 0.099 12.5 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase Synaphin PF05835.12 RUS78014.1 - 0.1 12.9 0.7 0.18 12.1 0.7 1.3 1 0 0 1 1 1 0 Synaphin protein AAA_7 PF12775.7 RUS78014.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 RUS78014.1 - 0.15 12.5 0.1 0.47 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NOA36 PF06524.12 RUS78015.1 - 1.8e-150 500.4 43.3 2.2e-150 500.1 43.3 1.0 1 0 0 1 1 1 1 NOA36 protein Trypan_PARP PF05887.11 RUS78015.1 - 0.31 11.0 9.7 0.62 10.0 9.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRN3 PF05327.11 RUS78015.1 - 0.53 8.8 12.2 0.76 8.3 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 RUS78015.1 - 0.9 9.1 16.6 0.043 13.4 11.5 1.4 2 0 0 2 2 2 0 PPP4R2 GCIP PF13324.6 RUS78015.1 - 1.3 8.6 8.1 2 8.0 8.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SDA1 PF05285.12 RUS78015.1 - 2.9 7.2 20.9 0.03 13.7 12.3 1.8 2 0 0 2 2 2 0 SDA1 E1_DerP2_DerF2 PF02221.15 RUS78016.1 - 1.2e-19 71.1 0.2 1.8e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 RUS78016.1 - 0.18 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Anoctamin PF04547.12 RUS78017.1 - 5.1e-131 437.6 9.0 6.2e-131 437.3 9.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RUS78017.1 - 1.5e-23 83.7 2.3 7.7e-21 74.9 0.5 2.6 2 1 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Peptidase_A22B PF04258.13 RUS78018.1 - 6.9e-64 216.1 13.5 9e-64 215.7 13.5 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Alpha_L_fucos PF01120.17 RUS78019.1 - 3.1e-53 181.5 0.0 3.6e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 RUS78019.1 - 4.2e-21 75.3 0.0 1.1e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain MFS_1 PF07690.16 RUS78020.1 - 2.8e-17 62.7 27.9 4.8e-13 48.8 4.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS78020.1 - 6e-07 28.7 11.9 0.0014 17.6 2.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Romo1 PF10247.9 RUS78020.1 - 3.2 8.2 5.2 5.3 7.5 2.1 3.0 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Noggin PF05806.12 RUS78021.1 - 2e-28 99.8 11.0 2.5e-19 70.1 0.2 3.2 3 0 0 3 3 3 3 Noggin Noggin PF05806.12 RUS78022.1 - 4.6e-63 213.0 7.7 5.9e-63 212.7 7.7 1.1 1 0 0 1 1 1 1 Noggin YL1 PF05764.13 RUS78023.1 - 2.4e-05 24.6 7.3 2.6e-05 24.5 7.3 1.1 1 0 0 1 1 1 1 YL1 nuclear protein eIF3_subunit PF08597.10 RUS78023.1 - 0.00036 20.5 16.6 0.0005 20.1 16.6 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GAGA_bind PF06217.12 RUS78023.1 - 0.00047 20.5 4.2 0.0005 20.4 4.2 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family RPN2_C PF18004.1 RUS78023.1 - 0.00082 19.3 12.2 0.0012 18.8 12.2 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain SR-25 PF10500.9 RUS78023.1 - 0.00091 18.9 16.1 0.00091 18.9 16.1 1.5 2 0 0 2 2 1 1 Nuclear RNA-splicing-associated protein Ferlin_C PF16165.5 RUS78023.1 - 0.0028 17.6 6.5 0.0044 17.0 6.5 1.3 1 0 0 1 1 1 1 Ferlin C-terminus AP3D1 PF06375.11 RUS78023.1 - 0.0062 16.8 15.1 0.0091 16.3 15.1 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 TFIIF_alpha PF05793.12 RUS78023.1 - 0.01 14.5 19.1 0.013 14.1 19.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4604 PF15377.6 RUS78023.1 - 0.029 14.8 18.0 0.04 14.4 18.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Ribosomal_S2 PF00318.20 RUS78023.1 - 0.04 13.1 2.6 0.05 12.8 2.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 CDC45 PF02724.14 RUS78023.1 - 0.047 12.0 4.7 0.048 12.0 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC106 PF15794.5 RUS78023.1 - 0.079 12.7 11.7 0.12 12.1 11.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_polI_A34 PF08208.11 RUS78023.1 - 0.22 11.6 25.2 0.32 11.1 25.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3381 PF11861.8 RUS78023.1 - 0.26 11.1 19.9 0.39 10.5 19.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_S49_N PF08496.10 RUS78023.1 - 0.37 10.8 13.2 0.53 10.3 13.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Jak1_Phl PF17887.1 RUS78023.1 - 0.76 9.7 10.7 1.4 8.9 10.7 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF3807 PF12720.7 RUS78023.1 - 0.85 9.9 12.9 1.3 9.3 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Med19 PF10278.9 RUS78023.1 - 1.1 9.2 21.4 1.4 8.8 21.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 YqfQ PF14181.6 RUS78023.1 - 1.1 9.5 12.0 1.7 8.8 12.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein HA2 PF04408.23 RUS78023.1 - 1.3 9.3 4.1 2.1 8.7 4.1 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) Presenilin PF01080.17 RUS78023.1 - 1.6 7.4 4.2 2 7.1 4.2 1.1 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 RUS78023.1 - 1.7 7.9 7.7 2.1 7.6 7.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Coilin_N PF15862.5 RUS78023.1 - 1.9 8.3 15.7 3.1 7.6 15.7 1.4 1 0 0 1 1 1 0 Coilin N-terminus Connexin PF00029.19 RUS78023.1 - 2 8.1 8.0 2.9 7.6 8.0 1.2 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 RUS78023.1 - 3.1 7.6 14.4 4 7.2 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cnd1_N PF12922.7 RUS78023.1 - 3.3 7.5 9.8 5.8 6.8 9.8 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term ETRAMP PF09716.10 RUS78023.1 - 3.8 7.6 13.2 6.1 7.0 13.2 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BCIP PF13862.6 RUS78023.1 - 4.9 6.9 11.4 6.4 6.5 11.4 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein OAD_gamma PF04277.13 RUS78023.1 - 6.2 7.5 7.9 12 6.6 7.9 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TPR_12 PF13424.6 RUS78025.1 - 2.9e-10 40.3 15.3 0.037 14.3 0.0 8.3 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS78025.1 - 7.3e-10 38.2 28.9 0.0057 16.7 0.2 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 RUS78025.1 - 4.5e-09 36.7 17.7 0.0011 19.4 1.1 6.9 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 RUS78025.1 - 5.3e-07 29.2 27.3 0.037 13.9 0.3 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS78025.1 - 6.6e-06 26.3 27.4 0.0002 21.5 7.6 5.7 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS78025.1 - 0.00016 22.2 4.9 0.24 12.3 0.1 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS78025.1 - 0.00096 19.0 11.2 0.19 11.8 0.3 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS78025.1 - 0.0013 19.3 14.2 0.21 12.3 0.2 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RUS78025.1 - 0.0018 17.9 3.2 0.022 14.4 0.1 4.0 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 RUS78025.1 - 0.0047 17.6 6.0 17 6.2 0.1 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS78025.1 - 0.02 15.1 22.3 1.6 9.1 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat BEX PF04538.12 RUS78025.1 - 0.041 14.5 1.5 0.088 13.4 0.1 2.1 2 0 0 2 2 2 0 Brain expressed X-linked like family LMBR1 PF04791.16 RUS78025.1 - 0.2 10.6 2.4 0.35 9.7 2.4 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein SlyX PF04102.12 RUS78025.1 - 1.4 9.6 7.5 4.6 7.9 1.1 4.0 4 0 0 4 4 4 0 SlyX COG2 PF06148.11 RUS78025.1 - 4.4 7.4 6.9 4.7 7.3 0.5 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 KTI12 PF08433.10 RUS78026.1 - 2.7e-101 338.6 0.1 3e-101 338.4 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 RUS78026.1 - 4.9e-09 36.5 0.1 1.6e-08 34.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RUS78026.1 - 0.032 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 RUS78026.1 - 0.042 13.2 0.0 0.065 12.5 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SRP54 PF00448.22 RUS78026.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 RUS78026.1 - 0.082 13.3 0.1 0.25 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 RUS78026.1 - 0.091 13.3 0.0 0.2 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain M_domain PF12938.7 RUS78027.1 - 8.7e-09 35.5 34.6 8.7e-09 35.5 34.6 4.5 3 1 0 4 4 4 1 M domain of GW182 RRM_1 PF00076.22 RUS78027.1 - 9.1e-07 28.6 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA PF00627.31 RUS78027.1 - 3.1e-06 27.0 0.2 7.9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RRM_occluded PF16842.5 RUS78027.1 - 0.023 14.6 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4148 PF13663.6 RUS78027.1 - 0.034 14.3 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) WD40 PF00400.32 RUS78028.1 - 1e-18 67.3 16.7 0.00026 21.7 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS78028.1 - 1e-10 41.8 0.4 0.00052 20.3 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS78028.1 - 0.0029 17.5 1.5 0.0064 16.4 0.3 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Syncollin PF15138.6 RUS78028.1 - 0.057 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Syncollin DUF3456 PF11938.8 RUS78029.1 - 6.5e-45 153.4 4.1 6.5e-45 153.4 4.1 1.5 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP Nucleopor_Nup85 PF07575.13 RUS78030.1 - 1.1e-151 506.2 20.3 1.3e-151 506.0 20.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Aa_trans PF01490.18 RUS78031.1 - 2.1e-16 59.7 26.7 5.6e-09 35.2 16.8 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RUS78031.1 - 0.0027 16.8 1.9 0.0027 16.8 1.9 3.4 3 1 0 3 3 3 1 Tryptophan/tyrosine permease family Cadherin_C_2 PF16492.5 RUS78031.1 - 0.78 10.5 0.1 0.78 10.5 0.1 3.0 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal AIP3 PF03915.13 RUS78033.1 - 0.02 14.0 0.2 0.03 13.4 0.2 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 bZIP_1 PF00170.21 RUS78033.1 - 0.041 14.0 1.6 1.2 9.3 0.1 2.6 3 0 0 3 3 3 0 bZIP transcription factor HSBP1 PF06825.12 RUS78033.1 - 0.057 13.3 0.1 32 4.5 0.0 3.2 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Med30 PF11315.8 RUS78033.1 - 0.066 13.4 0.0 8 6.7 0.0 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 WXG100 PF06013.12 RUS78033.1 - 0.067 13.4 0.0 13 6.1 0.0 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG CLZ PF16526.5 RUS78033.1 - 0.086 13.2 1.1 2.1 8.7 0.2 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vac_Fusion PF02346.16 RUS78033.1 - 0.089 12.4 0.1 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Peptidase_M75 PF09375.10 RUS78033.1 - 0.091 12.2 0.4 8.7 5.7 0.1 2.5 1 1 2 3 3 3 0 Imelysin Cep57_MT_bd PF06657.13 RUS78033.1 - 0.11 12.9 0.7 0.52 10.8 0.3 2.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.10 RUS78033.1 - 0.12 12.2 1.0 1.5 8.6 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4709 PF15821.5 RUS78033.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) DUF4715 PF15835.5 RUS78033.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) 7tm_2 PF00002.24 RUS78034.1 - 3.9e-11 42.7 13.9 1.5e-10 40.8 13.9 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF5510 PF17629.2 RUS78035.1 - 0.05 13.5 0.5 0.074 13.0 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5510) DNA_pol_B_exo1 PF03104.19 RUS78038.1 - 0.00016 20.9 0.6 0.00032 19.9 0.0 1.8 1 1 1 2 2 2 1 DNA polymerase family B, exonuclease domain DUF3760 PF12586.8 RUS78040.1 - 3.4e-17 62.3 15.9 0.5 10.6 0.0 10.7 12 0 0 12 12 12 6 Protein of unknown function (DUF3760) Inhibitor_I36 PF03995.13 RUS78040.1 - 0.00057 19.8 21.7 20 5.2 0.0 8.8 9 0 0 9 9 9 3 Peptidase inhibitor family I36 Rubredoxin_2 PF18073.1 RUS78040.1 - 0.11 12.3 34.0 32 4.4 0.1 9.9 10 0 0 10 10 10 0 Rubredoxin metal binding domain DUF3443 PF11925.8 RUS78040.1 - 0.61 8.9 9.1 1 8.1 0.0 4.7 3 2 1 5 5 5 0 Protein of unknown function (DUF3443) PTEN_C2 PF10409.9 RUS78041.1 - 6.1e-35 119.9 0.3 9.6e-35 119.3 0.3 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RUS78041.1 - 8.8e-06 25.6 0.8 7.8e-05 22.5 0.1 2.2 1 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS78041.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS78041.1 - 0.0044 17.0 0.2 0.0078 16.2 0.2 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RUS78041.1 - 0.0066 16.6 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPn PF14671.6 RUS78041.1 - 0.015 15.8 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half SAD_SRA PF02182.17 RUS78042.1 - 9.2e-57 191.1 0.2 1.9e-56 190.1 0.2 1.5 1 0 0 1 1 1 1 SAD/SRA domain TTD PF12148.8 RUS78042.1 - 7.1e-38 129.9 0.0 1.5e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 PHD PF00628.29 RUS78042.1 - 1.3e-13 50.6 7.7 1.3e-13 50.6 7.7 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RUS78042.1 - 0.0074 15.8 0.5 0.0074 15.8 0.5 2.3 2 0 0 2 2 2 1 PHD-finger HypA PF01155.19 RUS78042.1 - 1.2 9.2 12.2 7.8 6.6 3.0 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_2 PF13639.6 RUS78042.1 - 4.4 7.7 18.0 0.036 14.4 8.3 2.4 1 1 1 2 2 2 0 Ring finger domain Glyco_transf_11 PF01531.16 RUS78043.1 - 1e-27 97.1 0.2 2.9e-14 53.0 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 11 SOSSC PF15925.5 RUS78044.1 - 8.9e-21 75.1 0.3 1.5e-20 74.4 0.2 1.4 1 1 0 1 1 1 1 SOSS complex subunit C Ank_2 PF12796.7 RUS78045.1 - 1.2e-22 80.2 0.1 3.8e-12 46.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78045.1 - 8.1e-18 64.6 0.0 0.0005 20.6 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS78045.1 - 5.4e-17 61.6 0.1 2e-08 34.3 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 RUS78045.1 - 2.8e-16 59.5 12.5 5.2e-16 58.6 12.5 1.5 1 1 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 RUS78045.1 - 5.6e-16 57.0 1.3 0.0018 18.6 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 RUS78045.1 - 1.8e-12 47.1 0.1 0.00074 19.9 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat PKD_channel PF08016.12 RUS78045.1 - 0.00037 19.3 21.2 0.00096 17.9 12.6 2.9 2 1 0 2 2 2 1 Polycystin cation channel SKA2 PF16740.5 RUS78045.1 - 0.0025 17.6 0.2 0.0076 16.0 0.2 1.8 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF547 PF04784.14 RUS78046.1 - 4.1e-36 123.7 0.0 5.9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF1134 PF06577.12 RUS78046.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) FANC_SAP PF18081.1 RUS78049.1 - 0.086 13.0 0.6 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Nop14 PF04147.12 RUS78050.1 - 0.077 11.2 47.2 0.097 10.9 47.2 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 RUS78050.1 - 0.25 11.3 10.4 0.6 10.0 10.4 1.7 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 RUS78050.1 - 0.5 9.7 39.3 0.69 9.2 39.3 1.1 1 0 0 1 1 1 0 BUD22 Adap_comp_sub PF00928.21 RUS78051.1 - 8.9e-27 94.1 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF4658 PF15555.6 RUS78051.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) DSPc PF00782.20 RUS78052.1 - 4.7e-32 110.6 0.4 7.1e-32 110.0 0.1 1.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 RUS78052.1 - 0.0092 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) TNFR_c6 PF00020.18 RUS78053.1 - 3.3e-14 53.0 77.2 0.00014 22.2 3.7 9.7 8 2 2 10 10 10 9 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS78053.1 - 0.00013 21.7 1.4 0.00013 21.7 1.4 7.5 6 1 1 7 7 7 5 Putative ephrin-receptor like ABC1 PF03109.16 RUS78054.1 - 8.7e-36 122.7 0.0 1.6e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RUS78054.1 - 9.9e-08 31.7 0.1 3.2e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 RUS78054.1 - 0.00079 19.4 0.0 0.081 12.8 0.2 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RUS78054.1 - 0.023 14.3 0.6 0.041 13.5 0.1 1.7 2 0 0 2 2 2 0 RIO1 family CAP_GLY PF01302.25 RUS78055.1 - 1.7e-20 72.8 0.3 3e-20 72.0 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 RUS78055.1 - 1e-10 41.4 2.0 1.5e-08 34.3 0.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 RUS78055.1 - 3e-10 40.2 13.3 0.0035 17.7 0.8 5.4 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS78055.1 - 8.7e-07 28.6 13.3 0.037 13.8 0.4 5.2 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 RUS78055.1 - 7.8e-05 22.4 11.1 7.7 6.9 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 RUS78055.1 - 0.035 14.6 7.0 47 5.1 0.0 5.7 5 2 0 5 5 5 0 Leucine Rich Repeat GTP_EFTU PF00009.27 RUS78057.1 - 1.1e-33 116.4 0.0 1.1e-33 116.4 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS78057.1 - 1.2e-06 28.6 0.1 1.2e-06 28.6 0.1 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 RUS78057.1 - 0.00058 20.1 0.1 0.0022 18.2 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS78057.1 - 3 7.7 10.5 0.28 11.1 0.2 3.1 2 1 1 3 3 3 0 RsgA GTPase Bromo_TP PF07524.13 RUS78059.1 - 5e-12 45.7 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Pneumo_att_G PF05539.11 RUS78059.1 - 5 6.6 9.7 7.8 6.0 9.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Trp_dioxygenase PF03301.13 RUS78060.1 - 5.7e-137 456.7 6.8 6.8e-137 456.5 6.8 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Ank_2 PF12796.7 RUS78062.1 - 3e-74 245.6 2.9 3.4e-17 62.8 0.0 8.2 3 1 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78062.1 - 1.2e-69 229.8 15.3 5.5e-09 36.4 0.0 10.7 1 1 10 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 RUS78062.1 - 1.3e-53 177.2 15.9 3.4e-08 33.6 0.0 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 RUS78062.1 - 1.7e-43 141.6 0.1 7.1e-05 22.9 0.0 13.3 13 1 0 13 13 12 9 Ankyrin repeat Ank_5 PF13857.6 RUS78062.1 - 3.7e-35 119.5 17.0 3.3e-08 33.6 0.0 9.7 4 3 6 10 10 10 9 Ankyrin repeats (many copies) AAA_16 PF13191.6 RUS78062.1 - 4.5e-09 36.9 0.5 2.2e-08 34.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 RUS78062.1 - 0.0069 16.3 0.2 0.12 12.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 RUS78062.1 - 0.024 14.9 0.1 0.17 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 RUS78062.1 - 0.04 14.4 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 RUS78062.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ERAP1_C PF11838.8 RUS78062.1 - 0.14 11.6 5.8 0.85 9.1 0.1 3.3 3 1 0 3 3 3 0 ERAP1-like C-terminal domain Ras PF00071.22 RUS78063.1 - 1.1e-36 125.8 0.0 1.4e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78063.1 - 7.1e-13 48.8 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78063.1 - 7.5e-08 32.0 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS78063.1 - 8.3e-05 22.2 0.0 0.0017 17.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS78063.1 - 0.0027 17.8 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lig_chan PF00060.26 RUS78064.1 - 2.9e-27 95.3 0.1 3.8e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS78064.1 - 4.5e-25 88.1 0.0 8.7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS78064.1 - 2e-23 83.0 0.0 6.5e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF202 PF02656.15 RUS78064.1 - 0.77 10.2 3.8 1.5 9.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Helitron_like_N PF14214.6 RUS78067.1 - 1.6e-18 67.7 0.0 2.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus TSP_1 PF00090.19 RUS78069.1 - 2.6e-08 34.0 43.1 0.00013 22.1 6.2 4.9 4 1 0 4 4 4 3 Thrombospondin type 1 domain Ig_3 PF13927.6 RUS78069.1 - 1e-06 29.2 0.3 4.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS78069.1 - 5.3e-06 26.7 0.2 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS78069.1 - 7.5e-05 22.8 0.5 0.0012 19.0 0.1 3.0 2 1 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 RUS78069.1 - 0.00049 20.5 0.0 0.0016 18.8 0.0 1.9 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 RUS78069.1 - 0.003 17.7 0.0 3.6 7.8 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 RUS78069.1 - 0.071 13.2 0.0 0.47 10.5 0.0 2.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain Pyr_redox_2 PF07992.14 RUS78071.1 - 2e-64 217.7 0.1 2.8e-64 217.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 RUS78071.1 - 1.1e-19 70.2 0.4 2.6e-19 69.0 0.4 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 RUS78071.1 - 5.1e-18 65.4 3.1 5.9e-15 55.6 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS78071.1 - 2.2e-15 56.7 0.0 1e-13 51.2 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 RUS78071.1 - 3.7e-11 43.4 0.0 9.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 RUS78071.1 - 3.4e-10 39.8 0.0 8.6e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 RUS78071.1 - 4.1e-05 23.6 0.1 1.3 9.0 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 RUS78071.1 - 0.00015 20.6 0.0 4.1 6.0 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein NAD_binding_7 PF13241.6 RUS78071.1 - 0.00057 20.3 0.0 0.35 11.3 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.24 RUS78071.1 - 0.0014 18.3 0.0 0.4 10.2 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RUS78071.1 - 0.0076 16.5 0.0 0.03 14.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS78071.1 - 0.016 14.3 0.1 1.9 7.5 0.0 2.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 RUS78071.1 - 0.035 12.9 0.0 6.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NUDIX PF00293.28 RUS78072.1 - 7.3e-21 74.6 0.0 9.5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 RUS78072.1 - 0.0012 18.7 0.2 0.0025 17.8 0.2 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX_4 PF14815.6 RUS78072.1 - 0.0031 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Phage_int_SAM_5 PF13102.6 RUS78072.1 - 0.04 14.2 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain zf-RING_2 PF13639.6 RUS78072.1 - 8.7 6.8 7.1 61 4.1 4.9 2.3 2 0 0 2 2 2 0 Ring finger domain RF-1 PF00472.20 RUS78073.1 - 3.7e-24 84.9 0.9 7.7e-24 83.9 0.6 1.6 1 1 1 2 2 2 1 RF-1 domain Glyco_hydro_63 PF03200.16 RUS78074.1 - 4.7e-13 48.7 2.7 1.3e-07 30.7 0.1 4.2 3 1 0 3 3 3 3 Glycosyl hydrolase family 63 C-terminal domain Toprim_C_rpt PF13368.6 RUS78076.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat MFS_1 PF07690.16 RUS78077.1 - 2e-28 99.4 33.2 5.4e-28 97.9 33.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS78077.1 - 1.8e-24 86.5 5.5 1.8e-24 86.5 5.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter zf-LITAF-like PF10601.9 RUS78078.1 - 1.2e-18 67.1 4.9 1.5e-18 66.8 4.9 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DZR PF12773.7 RUS78078.1 - 0.00087 19.3 0.0 0.0014 18.6 0.0 1.3 1 1 0 1 1 1 1 Double zinc ribbon DNA_RNApol_7kD PF03604.13 RUS78078.1 - 0.021 14.5 0.8 4 7.2 0.0 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.17 RUS78078.1 - 0.088 12.5 1.9 0.5 10.1 0.4 2.3 2 1 0 2 2 2 0 Ribosomal protein S27 zf-ACC PF17848.1 RUS78078.1 - 0.13 12.4 5.2 3.3 7.9 0.5 2.6 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-RING_7 PF02591.15 RUS78078.1 - 0.28 11.4 3.8 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain Desulfoferrod_N PF06397.12 RUS78078.1 - 0.54 9.9 6.3 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-Mss51 PF13824.6 RUS78078.1 - 1 9.5 5.2 3.2 7.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Cys_rich_CPXG PF14255.6 RUS78078.1 - 1 9.3 0.1 1 9.3 0.1 2.9 2 1 1 3 3 3 0 Cysteine-rich CPXCG DUF4704 PF15787.5 RUS78079.1 - 0.025 13.8 1.1 0.028 13.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) MOR2-PAG1_C PF14225.6 RUS78079.1 - 0.036 13.9 0.5 0.045 13.6 0.4 1.3 1 1 0 1 1 1 0 Cell morphogenesis C-terminal GYF PF02213.16 RUS78080.1 - 2.3e-14 52.7 0.9 6.3e-14 51.4 0.9 1.8 1 0 0 1 1 1 1 GYF domain HEPN_LA2681 PF18733.1 RUS78080.1 - 0.034 13.4 0.3 0.056 12.7 0.3 1.3 1 0 0 1 1 1 0 LA2681-like HEPN GYF_2 PF14237.6 RUS78080.1 - 0.072 12.9 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 GYF domain 2 ALMT PF11744.8 RUS78080.1 - 0.84 8.4 5.1 1.2 7.9 5.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Sigma70_r3 PF04539.16 RUS78080.1 - 1.6 8.9 6.5 0.56 10.3 0.9 2.8 3 0 0 3 3 3 0 Sigma-70 region 3 Terminase_2 PF03592.16 RUS78080.1 - 1.8 9.0 7.1 0.4 11.1 1.5 2.3 1 1 0 2 2 2 0 Terminase small subunit A_deamin PF02137.18 RUS78081.1 - 2.3e-39 135.8 0.0 2.6e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 RUS78082.1 - 6e-10 39.7 0.3 1.7e-09 38.3 0.3 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif A_deamin PF02137.18 RUS78082.1 - 1.6e-09 37.7 0.2 5.9e-09 35.8 0.0 2.0 2 1 0 2 2 2 1 Adenosine-deaminase (editase) domain DUF4699 PF15770.5 RUS78083.1 - 0.31 10.8 7.0 0.65 9.7 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4699) DUF716 PF04819.12 RUS78084.1 - 1.3e-10 41.1 7.1 1.3e-10 41.1 7.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF716) TUDOR PF00567.24 RUS78085.1 - 1.1e-29 103.0 0.0 1.8e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 RUS78085.1 - 2.2e-10 40.2 0.0 5.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 KH domain DRY_EERY PF09750.9 RUS78086.1 - 1.2e-30 106.6 1.0 1.2e-30 106.6 1.0 4.5 5 0 0 5 5 5 1 Alternative splicing regulator Surp PF01805.20 RUS78086.1 - 5.2e-29 100.0 3.6 1.6e-13 50.4 0.8 2.9 2 0 0 2 2 2 2 Surp module LsmAD PF06741.13 RUS78087.1 - 2.9e-11 43.8 5.3 7.4e-11 42.4 5.3 1.8 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 RUS78087.1 - 9.1e-05 21.9 1.2 0.00028 20.3 1.2 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region SM-ATX PF14438.6 RUS78087.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Sulfotransfer_1 PF00685.27 RUS78088.1 - 4.7e-52 177.1 0.0 2.6e-51 174.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS78088.1 - 4.4e-05 24.0 0.0 0.003 18.0 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family DUF4649 PF15507.6 RUS78088.1 - 0.063 13.3 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) DctA-YdbH PF11739.8 RUS78090.1 - 1.9e-37 129.0 5.3 3.1 7.5 5.3 19.7 1 1 0 1 1 1 1 Dicarboxylate transport CAF-1_p150 PF11600.8 RUS78090.1 - 2e-17 63.4 82.2 1.5 8.5 9.1 13.3 1 1 3 5 5 5 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF874 PF05917.11 RUS78090.1 - 3.1e-13 49.5 0.0 8.2 5.4 0.0 8.9 1 1 10 11 11 11 11 Helicobacter pylori protein of unknown function (DUF874) ARL6IP6 PF15062.6 RUS78091.1 - 0.34 11.1 1.8 1.6 8.9 0.0 3.0 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix MYCBPAP PF14646.6 RUS78092.1 - 5.6e-96 322.1 0.2 6.6e-95 318.6 0.2 2.3 1 1 0 1 1 1 1 MYCBP-associated protein family AflR PF08493.10 RUS78093.1 - 0.012 15.2 3.2 0.013 15.0 3.2 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF5529 PF17669.1 RUS78093.1 - 0.67 10.0 8.1 7.6 6.5 8.1 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5529) AMPKBI PF04739.15 RUS78094.1 - 0.015 15.6 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain Macoilin PF09726.9 RUS78095.1 - 4.5 5.7 10.4 0.21 10.1 5.2 1.4 1 1 1 2 2 2 0 Macoilin family Sin3a_C PF16879.5 RUS78096.1 - 1.1e-58 199.3 1.2 1.7e-56 192.0 1.0 2.8 2 0 0 2 2 2 2 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 RUS78096.1 - 4.2e-39 132.6 0.0 1.1e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 RUS78096.1 - 4.8e-24 84.2 11.5 1.5e-17 63.5 0.4 2.9 3 0 0 3 3 3 2 Paired amphipathic helix repeat YcaO_C PF18381.1 RUS78096.1 - 0.05 13.5 0.6 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Fringe PF02434.16 RUS78097.1 - 1.5e-08 34.4 0.9 9.1e-08 31.8 0.9 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS78097.1 - 5.7e-05 23.0 0.3 0.00011 22.0 0.3 1.4 1 0 0 1 1 1 1 Galactosyltransferase Prok-RING_2 PF14445.6 RUS78098.1 - 0.028 14.6 0.8 0.046 13.9 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Pkinase_Tyr PF07714.17 RUS78099.1 - 6e-52 176.5 0.1 6.5e-52 176.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS78099.1 - 9.5e-33 113.7 0.1 1e-32 113.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 RUS78099.1 - 0.0002 21.0 0.0 0.01 15.5 0.0 2.0 1 1 1 2 2 2 2 RIO1 family Haspin_kinase PF12330.8 RUS78099.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain SH2 PF00017.24 RUS78100.1 - 3e-11 43.2 1.5 5.3e-11 42.5 0.2 2.2 2 0 0 2 2 2 1 SH2 domain FCH PF00611.23 RUS78100.1 - 1.8e-10 41.0 0.3 8.8e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Streptin-Immun PF11083.8 RUS78100.1 - 0.28 11.6 7.2 0.43 11.0 3.6 2.7 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein SpecificRecomb PF10136.9 RUS78100.1 - 0.34 9.2 2.6 0.19 10.0 0.3 1.7 2 0 0 2 2 2 0 Site-specific recombinase DUF724 PF05266.14 RUS78100.1 - 5.2 6.9 10.5 1.4 8.7 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF948 PF06103.11 RUS78100.1 - 9.7 6.5 9.0 8.4 6.7 1.6 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) B12D PF06522.11 RUS78102.1 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DEFB136 PF17333.2 RUS78104.1 - 0.0042 17.0 14.4 0.011 15.7 3.9 2.7 2 1 0 2 2 2 2 Beta defensin 136 TIL PF01826.17 RUS78104.1 - 5.8 7.2 30.0 17 5.7 11.3 2.7 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 RUS78105.1 - 0.61 10.4 29.6 3.7 7.9 11.3 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain C_tripleX PF02363.19 RUS78105.1 - 2.3 8.7 29.0 13 6.4 4.0 5.5 5 0 0 5 5 5 0 Cysteine rich repeat AROS PF15684.5 RUS78106.1 - 1.2e-18 67.9 19.4 1.6e-18 67.5 19.4 1.2 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF3450 PF11932.8 RUS78106.1 - 0.08 12.2 7.4 0.13 11.6 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) P22_AR_N PF10547.9 RUS78106.1 - 0.8 10.1 4.4 1.2 9.4 3.6 1.7 1 1 1 2 2 2 0 P22_AR N-terminal domain GCN5L1 PF06320.13 RUS78106.1 - 0.93 9.7 10.8 0.1 12.8 6.8 1.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) RhoGAP PF00620.27 RUS78107.1 - 2.3e-42 144.4 0.0 4.6e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 RUS78107.1 - 3.6e-40 138.1 4.5 5e-40 137.6 4.5 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RUS78107.1 - 0.00053 19.2 3.9 0.0011 18.2 3.9 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 RUS78107.1 - 0.019 14.7 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Vps5 PF09325.10 RUS78107.1 - 2.8 7.4 5.6 5.6 6.4 1.4 2.3 2 0 0 2 2 2 0 Vps5 C terminal like RRS1 PF04939.12 RUS78108.1 - 8.1e-53 178.6 13.8 8.1e-53 178.6 13.8 2.3 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) TBD PF12845.7 RUS78108.1 - 0.19 11.6 1.9 11 6.0 0.1 2.8 2 1 0 2 2 2 0 TBD domain G-patch_2 PF12656.7 RUS78108.1 - 1.6 8.9 5.6 0.55 10.4 1.1 2.6 2 0 0 2 2 2 0 G-patch domain Pribosyl_synth PF14572.6 RUS78109.1 - 4.2e-91 304.0 0.9 6.1e-91 303.4 0.9 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 RUS78109.1 - 3.7e-38 130.0 0.2 7.7e-38 129.0 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 RUS78109.1 - 1.5e-08 34.3 0.4 5.2e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Abhydrolase_3 PF07859.13 RUS78110.1 - 6.7e-51 173.1 0.5 5.8e-37 127.6 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 RUS78110.1 - 1.2e-05 24.4 0.5 5.1e-05 22.3 0.5 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS78110.1 - 0.00061 19.3 0.1 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 RUS78110.1 - 0.0089 15.5 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Say1_Mug180 PF10340.9 RUS78110.1 - 0.03 13.2 0.0 0.097 11.5 0.0 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 RUS78110.1 - 0.16 10.6 0.0 0.3 9.7 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMMECR1 PF01871.17 RUS78110.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 Pyridoxal_deC PF00282.19 RUS78111.1 - 7.8e-20 70.9 0.0 1.6e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RUS78111.1 - 3.5e-12 45.9 0.0 8.7e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RUS78111.1 - 2.4e-06 27.1 0.1 3.9e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 RUS78111.1 - 0.036 12.7 0.4 0.076 11.7 0.0 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 RUS78111.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Njmu-R1 PF15053.6 RUS78112.1 - 3.9e-39 134.8 0.1 2.4e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Mjmu-R1-like protein family Dynactin_p62 PF05502.13 RUS78113.1 - 1.6e-27 96.5 16.9 9.2e-21 74.2 11.4 2.2 2 0 0 2 2 2 2 Dynactin p62 family NuiA PF07924.11 RUS78114.1 - 0.1 13.0 0.3 0.44 10.9 0.1 1.8 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein BRX_assoc PF16627.5 RUS78114.1 - 3 8.1 12.4 0.92 9.7 1.6 2.7 2 1 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Smg8_Smg9 PF10220.9 RUS78116.1 - 1.3e-235 784.8 2.2 3.5e-235 783.3 2.2 1.7 1 1 0 1 1 1 1 Smg8_Smg9 CN_hydrolase PF00795.22 RUS78117.1 - 3.4e-14 52.8 0.0 5.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_M13 PF01431.21 RUS78118.1 - 2.8e-73 245.9 0.1 6.8e-63 212.0 0.1 2.4 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 RUS78118.1 - 1.9e-50 172.7 0.2 2.9e-50 172.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 RUS78119.1 - 7.3e-22 78.6 0.0 9.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 CbtB PF09489.10 RUS78119.1 - 0.19 11.9 0.5 0.37 10.9 0.5 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) UPF0489 PF12640.7 RUS78120.1 - 1.1e-20 74.6 0.6 4.7e-17 62.8 0.6 2.9 1 1 0 1 1 1 1 UPF0489 domain Arginase PF00491.21 RUS78120.1 - 0.027 14.0 2.0 2.6 7.5 0.1 2.2 1 1 1 2 2 2 0 Arginase family MafB19-deam PF14437.6 RUS78121.1 - 1.8e-22 79.6 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 RUS78121.1 - 2.7e-22 78.5 1.0 4.7e-22 77.8 1.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 RUS78121.1 - 0.00068 19.7 0.6 0.0027 17.8 0.6 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase mTERF PF02536.14 RUS78121.1 - 0.0024 16.9 0.0 0.0057 15.6 0.0 1.6 2 0 0 2 2 2 1 mTERF SNAD4 PF18750.1 RUS78121.1 - 0.027 14.6 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 AF-4 PF05110.13 RUS78121.1 - 4.7 5.2 10.3 6.3 4.7 10.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ABC2_membrane PF01061.24 RUS78122.1 - 0.0086 15.5 2.7 0.013 14.9 0.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter DUF3397 PF11877.8 RUS78122.1 - 0.39 10.9 4.5 0.24 11.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) UN_NPL4 PF11543.8 RUS78123.1 - 0.029 14.8 0.0 7.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DDRGK PF09756.9 RUS78124.1 - 0.035 13.7 19.2 0.053 13.1 19.2 1.2 1 0 0 1 1 1 0 DDRGK domain DUF5401 PF17380.2 RUS78124.1 - 0.068 11.2 14.5 0.076 11.1 14.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MMR1 PF08505.10 RUS78124.1 - 0.24 11.7 5.5 0.34 11.2 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 RUS78124.1 - 0.48 9.1 0.9 0.46 9.2 0.9 1.1 1 0 0 1 1 1 0 Presenilin U79_P34 PF03064.16 RUS78124.1 - 0.82 9.0 9.8 1.1 8.5 9.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PPL5 PF18168.1 RUS78124.1 - 1.1 8.5 4.2 1.7 7.8 4.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 FAM178 PF14816.6 RUS78124.1 - 1.7 7.5 8.3 2.4 7.0 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 CDC45 PF02724.14 RUS78124.1 - 1.9 6.7 7.3 2 6.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 RUS78124.1 - 2.5 7.4 6.5 4 6.7 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EF-hand_7 PF13499.6 RUS78125.1 - 4e-17 62.4 1.6 1.4e-08 35.1 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS78125.1 - 5.4e-16 56.9 0.4 0.0005 19.4 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS78125.1 - 2.5e-14 51.9 1.7 0.00012 21.7 0.0 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 RUS78125.1 - 1.7e-08 34.2 5.5 6.6e-07 29.1 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS78125.1 - 4.2e-07 29.2 3.2 0.094 12.3 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 RUS78125.1 - 7.7e-05 22.9 0.0 0.052 13.9 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS78125.1 - 0.0021 18.0 0.2 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 RUS78125.1 - 0.01 16.7 0.0 0.07 14.0 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 RUS78125.1 - 0.034 14.5 0.1 0.13 12.6 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain AsiA PF09010.10 RUS78125.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Anti-Sigma Factor A Secretogranin_V PF05281.11 RUS78126.1 - 1.3e-20 74.0 0.1 1.7e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) Glycos_transf_2 PF00535.26 RUS78127.1 - 3.2e-28 98.6 0.0 4.4e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 RUS78127.1 - 0.00089 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.8 RUS78127.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Glyco_tranf_2_2 PF10111.9 RUS78127.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Put_DNA-bind_N PF06971.13 RUS78129.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus PPR_long PF17177.4 RUS78129.1 - 0.027 13.8 0.1 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP AAA_6 PF12774.7 RUS78130.1 - 1.1e-139 465.0 0.1 4.4e-137 456.4 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 RUS78130.1 - 1.1e-105 352.6 0.0 5.5e-105 350.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 RUS78130.1 - 2.9e-100 336.2 0.0 2.9e-100 336.2 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RUS78130.1 - 4.2e-94 313.8 1.1 1.5e-93 311.9 1.1 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 RUS78130.1 - 1e-81 274.6 0.1 9e-81 271.4 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RUS78130.1 - 4.8e-78 260.8 0.6 5.9e-71 237.7 0.0 5.1 4 1 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 RUS78130.1 - 2.2e-55 188.1 18.1 4.6e-55 187.0 18.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RUS78130.1 - 6.2e-54 182.2 0.0 2.1e-53 180.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RUS78130.1 - 6.3e-26 90.8 0.0 2.3e-23 82.5 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RUS78130.1 - 8e-24 83.7 0.3 3.9e-23 81.5 0.3 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RUS78130.1 - 9.9e-23 80.6 4.5 1.4e-22 80.2 1.8 2.9 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS78130.1 - 3e-19 69.4 0.0 2.3e-07 30.9 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS78130.1 - 8.1e-12 45.7 0.5 0.031 14.7 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RUS78130.1 - 1.9e-10 41.4 0.5 0.0063 17.1 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 RUS78130.1 - 5.9e-09 36.3 0.0 0.082 13.2 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 RUS78130.1 - 1.3e-08 35.4 6.5 0.29 11.5 0.0 5.9 5 2 1 6 6 5 3 AAA ATPase domain RNA_helicase PF00910.22 RUS78130.1 - 1.5e-06 28.5 0.0 2 8.9 0.0 3.8 3 0 0 3 3 3 1 RNA helicase Sigma54_activat PF00158.26 RUS78130.1 - 1.1e-05 25.2 0.1 0.11 12.1 0.0 3.8 4 0 0 4 4 3 1 Sigma-54 interaction domain TsaE PF02367.17 RUS78130.1 - 3e-05 24.0 0.4 3.1 7.8 0.0 5.1 5 0 0 5 5 5 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 RUS78130.1 - 4.5e-05 22.2 0.3 0.11 11.0 0.0 3.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) NACHT PF05729.12 RUS78130.1 - 0.00032 20.7 0.1 0.3 11.0 0.0 3.9 4 0 0 4 4 3 1 NACHT domain AAA_14 PF13173.6 RUS78130.1 - 0.00069 19.7 0.1 0.58 10.2 0.0 4.5 4 0 0 4 4 3 1 AAA domain T2SSE PF00437.20 RUS78130.1 - 0.00075 18.6 4.2 0.2 10.7 0.1 3.9 5 0 0 5 5 4 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 RUS78130.1 - 0.0022 16.9 0.6 0.36 9.7 0.0 3.4 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 RUS78130.1 - 0.0025 17.7 0.3 0.59 10.0 0.0 3.2 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_28 PF13521.6 RUS78130.1 - 0.0033 17.7 0.4 5.7 7.2 0.0 4.3 5 0 0 5 5 4 0 AAA domain AAA_29 PF13555.6 RUS78130.1 - 0.0047 16.6 0.3 3.7 7.4 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain PRK PF00485.18 RUS78130.1 - 0.0057 16.4 0.1 2.4 7.8 0.0 3.8 4 0 0 4 4 4 1 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 RUS78130.1 - 0.0071 16.3 0.1 3.2 7.6 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 RUS78130.1 - 0.0071 15.9 0.1 12 5.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 RUS78130.1 - 0.011 15.9 0.0 29 4.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 RUS78130.1 - 0.012 14.8 0.8 0.84 8.8 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain ABC_tran PF00005.27 RUS78130.1 - 0.014 15.9 1.4 0.28 11.7 0.0 3.3 3 0 0 3 3 2 0 ABC transporter Mg_chelatase PF01078.21 RUS78130.1 - 0.021 14.2 2.1 0.38 10.1 0.1 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RUS78130.1 - 0.063 12.5 0.0 43 3.3 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin Trans_reg_C PF00486.28 RUS78130.1 - 0.091 12.9 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal AAA_24 PF13479.6 RUS78130.1 - 0.16 11.7 0.2 53 3.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 RUS78130.1 - 0.31 10.9 7.3 1.1 9.2 0.0 4.3 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Roc PF08477.13 RUS78130.1 - 0.53 10.5 2.2 25 5.1 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 RUS78130.1 - 0.57 9.9 11.1 5.6 6.6 0.0 5.0 6 0 0 6 6 6 0 AAA domain AAA_19 PF13245.6 RUS78130.1 - 5.1 7.4 7.2 44 4.4 0.0 4.3 5 0 0 5 5 3 0 AAA domain Peptidase_M16_M PF16187.5 RUS78131.1 - 3.3e-34 118.5 1.3 3.6e-34 118.4 1.3 1.0 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Dynein_C PF18199.1 RUS78132.1 - 2.2e-24 86.2 0.0 2.2e-24 86.2 0.0 1.8 2 1 0 2 2 1 1 Dynein heavy chain C-terminal domain BUD22 PF09073.10 RUS78132.1 - 8.1e-08 32.0 28.2 8.1e-08 32.0 28.2 1.5 2 0 0 2 2 2 1 BUD22 NPR3 PF03666.13 RUS78132.1 - 2.6e-07 29.8 15.9 3.2e-07 29.5 15.9 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 AAA_lid_11 PF18198.1 RUS78132.1 - 1.1e-06 28.6 0.1 2.6e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MCM_bind PF09739.9 RUS78132.1 - 9.7e-06 24.3 15.9 1.3e-05 23.9 15.9 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Pox_Ag35 PF03286.14 RUS78132.1 - 2.2e-05 24.4 29.6 4.1e-05 23.5 29.6 1.5 1 0 0 1 1 1 1 Pox virus Ag35 surface protein FAM60A PF15396.6 RUS78132.1 - 8.2e-05 22.7 14.4 0.00012 22.2 14.4 1.3 1 0 0 1 1 1 1 Protein Family FAM60A Zip PF02535.22 RUS78132.1 - 0.00022 20.6 9.2 0.00024 20.4 9.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Rrn6 PF10214.9 RUS78132.1 - 0.0022 16.6 9.0 0.0025 16.4 9.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF5308 PF17233.2 RUS78132.1 - 0.0075 16.5 2.6 0.013 15.8 2.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Cellulose_synt PF03552.14 RUS78132.1 - 0.024 13.2 9.5 0.03 12.9 9.5 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2151 PF10221.9 RUS78132.1 - 0.033 12.8 19.4 0.0088 14.7 16.8 1.4 2 0 0 2 2 2 0 Cell cycle and development regulator SR-25 PF10500.9 RUS78132.1 - 0.047 13.3 38.8 0.075 12.6 38.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ASC PF00858.24 RUS78132.1 - 0.074 12.0 4.2 0.069 12.1 4.2 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel PIP5K PF01504.18 RUS78132.1 - 0.11 11.8 13.2 0.3 10.3 13.2 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF913 PF06025.12 RUS78132.1 - 0.13 11.2 16.6 0.24 10.3 16.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 RUS78132.1 - 0.13 10.4 37.0 0.21 9.8 37.0 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 RUS78132.1 - 0.14 10.9 23.3 0.2 10.4 23.3 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 RUS78132.1 - 0.15 12.1 11.7 0.34 11.0 9.7 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Otopetrin PF03189.13 RUS78132.1 - 0.18 10.6 2.4 0.23 10.3 2.4 1.2 1 0 0 1 1 1 0 Otopetrin DUF4746 PF15928.5 RUS78132.1 - 0.19 11.1 37.9 0.31 10.4 37.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Raftlin PF15250.6 RUS78132.1 - 0.28 9.9 14.4 0.37 9.5 14.4 1.2 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 RUS78132.1 - 0.5 9.3 19.3 0.78 8.7 19.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FancD2 PF14631.6 RUS78132.1 - 0.51 7.7 22.0 0.8 7.0 22.0 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RPOL_N PF14700.6 RUS78132.1 - 0.6 9.4 24.4 0.94 8.8 24.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RNA_pol_3_Rpc31 PF11705.8 RUS78132.1 - 0.64 10.2 51.7 1 9.5 51.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-N PF05238.13 RUS78132.1 - 0.65 9.2 14.3 0.97 8.7 14.3 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4045 PF13254.6 RUS78132.1 - 0.74 9.4 23.8 1 9.0 23.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM76 PF16046.5 RUS78132.1 - 0.87 8.9 27.1 0.18 11.1 23.2 1.6 2 0 0 2 2 2 0 FAM76 protein CCDC53 PF10152.9 RUS78132.1 - 0.95 9.9 17.1 2 8.8 17.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rgp1 PF08737.10 RUS78132.1 - 0.97 8.5 15.1 1.5 7.9 15.1 1.2 1 0 0 1 1 1 0 Rgp1 NARP1 PF12569.8 RUS78132.1 - 1 8.2 35.2 1.8 7.4 35.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BORG_CEP PF14957.6 RUS78132.1 - 1.1 10.4 14.8 2.1 9.5 14.8 1.4 1 0 0 1 1 1 0 Cdc42 effector CDC27 PF09507.10 RUS78132.1 - 1.2 8.5 43.8 1.7 7.9 43.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4228 PF14009.6 RUS78132.1 - 1.4 9.3 9.0 2.2 8.7 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) MDM10 PF12519.8 RUS78132.1 - 1.4 7.7 19.6 2 7.2 19.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CENP-B_dimeris PF09026.10 RUS78132.1 - 1.5 9.2 27.9 40 4.7 27.9 2.3 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Spore_coat_CotO PF14153.6 RUS78132.1 - 1.8 8.5 36.1 3.6 7.5 36.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Nucleo_P87 PF07267.11 RUS78132.1 - 2.3 7.0 18.7 4.2 6.1 18.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CSRNP_N PF16019.5 RUS78132.1 - 2.3 8.1 20.9 1.1 9.1 18.7 1.5 2 0 0 2 2 1 0 Cysteine/serine-rich nuclear protein N-terminus SAPS PF04499.15 RUS78132.1 - 2.9 6.6 20.4 1.7 7.4 18.5 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.11 RUS78132.1 - 4 7.4 27.0 5.3 7.0 27.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ESM4 PF15952.5 RUS78132.1 - 5.7 7.3 16.8 1.4 9.4 13.4 1.7 2 0 0 2 2 2 0 Enhancer of split M4 family Hid1 PF12722.7 RUS78132.1 - 5.8 4.9 17.5 8.5 4.4 17.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 RUS78132.1 - 5.8 6.6 37.0 11 5.8 37.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Slu7 PF11708.8 RUS78132.1 - 9.8 5.8 34.9 17 5.0 34.9 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SAM_1 PF00536.30 RUS78133.1 - 8e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS78133.1 - 1.6e-12 47.3 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ABC1 PF03109.16 RUS78134.1 - 4.7e-35 120.3 0.0 9.1e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 RUS78135.1 - 1.4e-33 116.4 0.0 2.1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78135.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS78135.1 - 0.00027 19.8 0.0 0.00052 18.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS78135.1 - 0.0085 16.0 0.1 0.32 10.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS78135.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B56 PF01603.20 RUS78136.1 - 2.3e-195 649.4 11.2 2.9e-195 649.1 11.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 RUS78136.1 - 0.00097 19.1 4.4 0.31 10.9 0.3 3.0 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal MOR2-PAG1_C PF14225.6 RUS78136.1 - 0.064 13.1 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Cell morphogenesis C-terminal EF-hand_1 PF00036.32 RUS78137.1 - 3.1e-30 101.4 13.5 1.4e-09 36.8 0.2 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RUS78137.1 - 8e-28 96.1 9.3 3.2e-14 52.5 1.4 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 RUS78137.1 - 2.4e-25 88.8 5.2 3.1e-16 59.6 2.8 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS78137.1 - 2.1e-20 70.9 7.5 1.2e-09 37.3 0.1 3.5 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RUS78137.1 - 5.4e-19 66.8 10.8 3.2e-07 29.5 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 RUS78137.1 - 1.1e-10 41.6 0.3 0.00037 20.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS78137.1 - 1.5e-07 31.3 2.9 0.0004 20.3 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 RUS78137.1 - 4.2e-05 24.4 0.1 0.038 14.8 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS78137.1 - 0.00011 22.5 0.1 0.0056 17.0 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RUS78137.1 - 0.00017 21.7 3.4 0.082 13.1 0.4 3.0 1 1 2 3 3 3 3 Dockerin type I domain UPF0154 PF03672.13 RUS78137.1 - 0.00017 21.6 0.2 0.83 9.7 0.0 2.5 3 0 0 3 3 2 2 Uncharacterised protein family (UPF0154) DUF1296 PF06972.11 RUS78137.1 - 0.0037 17.4 1.5 0.29 11.3 0.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1296) EFhand_Ca_insen PF08726.10 RUS78137.1 - 0.0038 17.3 0.5 0.0083 16.2 0.2 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SurA_N_2 PF13623.6 RUS78137.1 - 0.0041 17.0 0.9 0.032 14.1 0.4 2.0 1 1 1 2 2 2 1 SurA N-terminal domain DUF5580 PF17743.1 RUS78137.1 - 0.0056 15.3 0.0 0.006 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Phage_TAC_12 PF12363.8 RUS78137.1 - 0.057 13.8 0.4 0.44 11.0 0.2 2.1 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC TFIIA_gamma_N PF02268.16 RUS78137.1 - 0.16 12.0 0.5 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain VWA PF00092.28 RUS78138.1 - 6.4e-31 107.9 0.1 8.1e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS78138.1 - 5.2e-09 36.7 0.0 7.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 RUS78138.1 - 0.02 14.3 0.3 0.025 14.0 0.3 1.4 1 1 0 1 1 1 0 Copine VWA_3 PF13768.6 RUS78138.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Eisosome1 PF12757.7 RUS78138.1 - 0.15 12.3 0.7 0.25 11.6 0.7 1.3 1 0 0 1 1 1 0 Eisosome protein 1 FAM183 PF14886.6 RUS78139.1 - 3.4e-31 108.2 0.3 4.1e-31 107.9 0.3 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related ChaC PF04752.12 RUS78140.1 - 9.8e-58 195.1 0.0 1.1e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 RUS78140.1 - 0.0058 17.2 0.0 0.0082 16.7 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pil1 PF13805.6 RUS78140.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 SCAN PF02023.17 RUS78141.1 - 4.5e-08 32.8 0.1 8.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 SCAN domain TRAP_alpha PF03896.16 RUS78141.1 - 3.2 6.9 7.1 4.1 6.5 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 RUS78141.1 - 7.3 6.3 8.2 9.8 5.9 8.2 1.3 1 0 0 1 1 1 0 Connexin MDM10 PF12519.8 RUS78141.1 - 8.6 5.1 6.7 10 4.9 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 7TM_GPCR_Srw PF10324.9 RUS78143.1 - 1.6e-09 37.5 16.4 2.9e-09 36.7 16.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS78143.1 - 1.1e-06 28.5 15.0 1.1e-06 28.5 15.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS78143.1 - 1.3e-05 24.7 12.0 2e-05 24.0 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1180 PF06679.12 RUS78144.1 - 0.83 10.0 4.0 1.2 9.5 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Band_7 PF01145.25 RUS78145.1 - 1.1e-24 87.5 0.3 1.2e-24 87.3 0.3 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family VPS9 PF02204.18 RUS78147.1 - 2.5e-25 88.7 0.1 6.9e-25 87.3 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 RUS78147.1 - 2.6e-22 79.6 0.0 4.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF5601 PF18151.1 RUS78147.1 - 2.9e-08 33.9 0.1 1.3e-07 31.8 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Glyco_hydro_47 PF01532.20 RUS78148.1 - 1.8e-112 376.6 0.0 3.6e-112 375.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 RUS78148.1 - 3.1e-11 43.1 0.0 7.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 PA domain TIR_2 PF13676.6 RUS78149.1 - 8.6e-27 94.1 0.2 2.4e-13 50.7 0.1 2.5 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 RUS78149.1 - 5.6e-13 49.1 3.3 4.8e-08 33.0 0.8 2.5 2 0 0 2 2 2 2 TIR domain Pox_P35 PF03213.14 RUS78149.1 - 0.016 14.4 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus P35 protein TetR_C_22 PF17928.1 RUS78149.1 - 0.09 13.1 0.1 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UPF0160 PF03690.13 RUS78149.1 - 0.095 12.3 1.5 0.15 11.7 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Colipase PF01114.18 RUS78149.1 - 0.17 11.6 0.8 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 Colipase, N-terminal domain DUF3767 PF12597.8 RUS78149.1 - 0.31 10.9 1.4 17 5.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) DUF1704 PF08014.11 RUS78150.1 - 1.1e-09 37.8 0.0 2.6e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) DnaJ_C PF01556.18 RUS78151.1 - 2.7e-43 147.6 0.2 4e-43 147.0 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS78151.1 - 4.6e-25 87.5 0.4 8.1e-25 86.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RUS78151.1 - 3.3e-16 59.4 18.3 5.8e-16 58.6 18.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 RUS78151.1 - 0.00013 21.8 13.9 0.03 14.3 3.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 RUS78151.1 - 0.013 15.5 10.3 0.49 10.4 2.8 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 RUS78151.1 - 2.1 8.4 9.5 3 7.9 0.7 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 RUS78151.1 - 4 7.5 11.6 1.1e+02 2.8 11.6 2.3 1 1 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 RUS78151.1 - 8.5 6.0 11.4 12 5.6 1.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Y_phosphatase PF00102.27 RUS78152.1 - 1.7e-63 214.3 0.2 2.1e-63 214.1 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS78152.1 - 0.00039 20.2 0.4 0.00068 19.4 0.4 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS78152.1 - 0.11 12.4 0.1 0.14 12.1 0.1 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family SH3_1 PF00018.28 RUS78153.1 - 2.9e-16 58.8 0.1 5.2e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS78153.1 - 1.7e-14 53.4 0.2 8.7e-14 51.1 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RUS78153.1 - 8.2e-14 51.0 0.0 1.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 RUS78153.1 - 0.00075 19.6 0.1 0.00075 19.6 0.1 2.3 2 1 1 3 3 3 1 Hr1 repeat RNAse_A_bac PF18431.1 RUS78153.1 - 0.18 12.7 1.1 0.45 11.5 1.1 1.7 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain betaPIX_CC PF16523.5 RUS78153.1 - 0.33 10.8 4.7 0.84 9.5 0.0 3.4 3 1 1 4 4 4 0 betaPIX coiled coil HD_assoc PF13286.6 RUS78153.1 - 0.44 11.1 3.3 0.24 11.9 0.4 2.1 2 1 0 2 2 2 0 Phosphohydrolase-associated domain DUF4398 PF14346.6 RUS78153.1 - 5.3 7.7 8.8 11 6.7 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) QVR PF17064.5 RUS78154.1 - 0.14 12.4 8.1 1.2 9.4 8.1 2.3 1 1 0 1 1 1 0 Sleepless protein Beta-lactamase PF00144.24 RUS78156.1 - 7.1e-56 189.8 0.1 8.9e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase p25-alpha PF05517.12 RUS78157.1 - 1.7e-26 93.2 5.3 2.4e-26 92.7 5.3 1.3 1 0 0 1 1 1 1 p25-alpha NFRKB_winged PF14465.6 RUS78158.1 - 0.0015 18.7 4.8 6.7 7.0 0.1 4.1 1 1 2 3 3 3 3 NFRKB Winged Helix-like MgtE_N PF03448.17 RUS78158.1 - 0.067 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain RNA_polI_A14 PF08203.11 RUS78158.1 - 0.17 12.6 5.7 7.1 7.4 0.8 3.6 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Imm6 PF14434.6 RUS78158.1 - 2.3 8.1 19.4 7 6.6 0.9 3.9 1 1 3 4 4 4 0 Immunity protein Imm6 Receptor_IA-2 PF11548.8 RUS78159.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase receptor IA-2 Glycophorin_A PF01102.18 RUS78159.1 - 0.018 15.3 0.0 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 Glycophorin A DUF3731 PF12531.8 RUS78159.1 - 0.036 13.9 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 DNA-K related protein P16-Arc PF04699.14 RUS78159.1 - 0.046 14.2 0.4 0.16 12.5 0.2 1.9 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) 7tm_1 PF00001.21 RUS78162.1 - 5e-11 42.4 22.6 7.3e-11 41.9 22.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS78162.1 - 3.1e-08 33.3 27.0 7.9e-08 31.9 27.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS78162.1 - 1.1e-05 25.2 16.9 1.1e-05 25.2 16.9 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HAD_2 PF13419.6 RUS78163.1 - 2.1e-20 73.6 0.0 3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS78163.1 - 3.6e-13 50.3 0.0 4.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS78163.1 - 7.1e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ACBP PF00887.19 RUS78164.1 - 2.7e-27 94.8 0.8 5.1e-27 93.9 0.8 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 RUS78164.1 - 4.6e-22 78.4 0.1 4.4e-11 43.2 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS78164.1 - 1.5e-18 66.6 0.2 4e-12 46.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS78164.1 - 2.1e-13 50.5 0.3 8e-11 42.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS78164.1 - 3.6e-11 43.0 0.0 0.00045 20.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RUS78164.1 - 2.4e-10 39.7 0.1 0.0057 17.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF632 PF04782.12 RUS78164.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Lectin_C PF00059.21 RUS78165.1 - 2.2e-16 60.5 0.3 4e-16 59.7 0.3 1.5 1 0 0 1 1 1 1 Lectin C-type domain Sushi PF00084.20 RUS78166.1 - 6.7e-65 215.5 63.9 9.3e-09 35.8 0.1 12.5 12 1 0 12 12 12 12 Sushi repeat (SCR repeat) GH43_C2 PF17851.1 RUS78167.1 - 0.19 11.4 6.0 4.4 7.0 1.5 2.9 1 1 1 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain RNase_H PF00075.24 RUS78168.1 - 2.3e-25 89.4 8.4 1.4e-12 48.0 0.9 2.4 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.6 RUS78168.1 - 8.9e-08 32.0 2.4 0.0075 16.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase-like HATPase_c_5 PF14501.6 RUS78168.1 - 0.00032 20.6 14.1 0.084 12.8 3.2 3.3 2 2 0 2 2 2 2 GHKL domain Pga1 PF10333.9 RUS78168.1 - 0.0025 17.7 7.1 0.41 10.5 0.8 2.3 2 0 0 2 2 2 2 GPI-Mannosyltransferase II co-activator dCMP_cyt_deam_1 PF00383.23 RUS78168.1 - 0.0082 16.0 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Frigida PF07899.11 RUS78168.1 - 0.015 14.6 5.6 1.1 8.5 0.5 2.3 2 0 0 2 2 2 0 Frigida-like protein YflT PF11181.8 RUS78168.1 - 0.015 15.8 4.6 2.9 8.5 0.4 2.7 2 0 0 2 2 2 0 Heat induced stress protein YflT P53_C PF11619.8 RUS78168.1 - 0.036 14.1 0.7 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain DUF4474 PF14751.6 RUS78168.1 - 0.06 12.8 2.6 1.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) PTSIIB_sorb PF03830.15 RUS78168.1 - 0.12 12.5 4.6 7 6.9 0.4 2.7 2 2 0 2 2 2 0 PTS system sorbose subfamily IIB component PhnJ PF06007.11 RUS78168.1 - 0.3 10.0 3.2 8.8 5.2 0.2 2.2 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnJ Fam20C PF06702.12 RUS78169.1 - 1.7e-75 253.6 0.0 2.9e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 MFS_1 PF07690.16 RUS78170.1 - 3e-06 26.4 2.4 8.4e-06 24.9 2.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2829 PF11195.8 RUS78170.1 - 0.15 12.3 0.1 0.57 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) DUF4535 PF15054.6 RUS78171.1 - 1.4e-05 24.8 0.0 0.00016 21.3 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4535) CCDC66 PF15236.6 RUS78173.1 - 3.3e-17 62.7 44.3 3.6e-17 62.6 44.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 DUF4407 PF14362.6 RUS78173.1 - 0.18 11.2 16.0 0.23 10.8 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 RUS78173.1 - 6.1 6.3 19.7 8.7 5.8 19.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DRY_EERY PF09750.9 RUS78173.1 - 6.8 7.0 19.9 9.5 6.5 19.9 1.2 1 0 0 1 1 1 0 Alternative splicing regulator AAA_11 PF13086.6 RUS78173.1 - 8.8 6.0 21.5 10 5.8 21.5 1.1 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 RUS78173.1 - 9.7 6.9 18.3 16 6.2 17.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA RNA_pol_Rpb5_C PF01191.19 RUS78175.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain PH_16 PF17838.1 RUS78176.1 - 1.3e-39 134.9 0.6 2.9e-39 133.8 0.6 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 RUS78176.1 - 4.4e-34 118.3 2.6 1e-33 117.1 2.6 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 RUS78176.1 - 0.026 15.0 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 PH domain HisKA PF00512.25 RUS78176.1 - 0.39 10.8 2.5 15 5.7 0.6 3.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain SUIM_assoc PF16619.5 RUS78176.1 - 2.2 8.4 12.8 0.054 13.6 4.5 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FGGY_N PF00370.21 RUS78178.1 - 1.6e-66 224.4 0.0 2.8e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RUS78178.1 - 1.5e-64 217.4 2.5 3.4e-64 216.2 2.5 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TSP_1 PF00090.19 RUS78178.1 - 5.1e-09 36.2 4.2 5.1e-09 36.2 4.2 8.2 10 0 0 10 10 10 1 Thrombospondin type 1 domain Peptidase_M14 PF00246.24 RUS78179.1 - 1.8e-65 221.7 0.0 2.8e-65 221.0 0.0 1.3 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 RUS78179.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Tae4 PF14113.6 RUS78181.1 - 1.5e-06 28.5 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system (T6SS), amidase effector protein 4 ANAPC4 PF12896.7 RUS78182.1 - 3.1e-28 98.7 0.1 5.4e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 CLAMP PF14769.6 RUS78182.1 - 9.2e-05 22.8 1.4 0.00019 21.9 0.2 2.2 3 0 0 3 3 3 1 Flagellar C1a complex subunit C1a-32 ANAPC4_WD40 PF12894.7 RUS78183.1 - 4.5e-28 97.4 0.1 1.9e-27 95.4 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 RUS78183.1 - 0.00054 19.5 1.2 0.00084 18.9 1.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF5122 PF17164.4 RUS78183.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller RhoGAP PF00620.27 RUS78184.1 - 7.2e-25 87.6 0.3 1.7e-24 86.4 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain 7TM_GPCR_Srx PF10328.9 RUS78186.1 - 5.3e-06 26.3 21.5 5.3e-06 26.3 21.5 2.4 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS78186.1 - 0.00063 19.2 23.2 0.00063 19.2 23.2 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 RUS78186.1 - 0.005 16.5 20.5 0.005 16.5 20.5 2.4 1 1 1 2 2 2 2 Srg family chemoreceptor Mucin PF01456.17 RUS78188.1 - 0.058 13.4 23.0 0.073 13.1 23.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SDA1 PF05285.12 RUS78189.1 - 0.00045 19.8 37.7 0.00056 19.5 37.7 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS78189.1 - 1.6 6.8 42.8 2.8 6.0 42.8 1.3 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 RUS78190.1 - 3.8 6.9 8.0 5.5 6.4 8.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein EGF_CA PF07645.15 RUS78191.1 - 9.3e-06 25.8 5.7 9.3e-06 25.8 5.7 4.4 4 2 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 RUS78191.1 - 1.1e-05 25.2 20.4 0.00027 20.8 0.5 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS78191.1 - 0.032 14.5 6.2 0.032 14.5 6.2 3.6 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site DUF4617 PF15395.6 RUS78191.1 - 2.5 6.3 3.8 3.4 5.8 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) SNF2_N PF00176.23 RUS78192.1 - 2.2e-27 95.7 0.1 3.5e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 RUS78192.1 - 2.3e-16 59.1 0.2 5.3e-16 58.0 0.2 1.7 1 0 0 1 1 1 1 HepA-related protein (HARP) Helicase_C PF00271.31 RUS78192.1 - 8.3e-15 55.1 0.3 3.6e-14 53.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS78192.1 - 2.1e-06 27.8 0.0 6.2e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 RUS78192.1 - 0.00043 20.3 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain Syntaxin-18_N PF10496.9 RUS78193.1 - 9.7e-17 61.0 1.3 9.7e-17 61.0 1.3 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 RUS78193.1 - 0.003 17.5 1.6 0.0035 17.3 0.1 1.9 2 0 0 2 2 2 1 SNARE domain DUF1593 PF07632.11 RUS78193.1 - 0.042 13.3 3.1 0.13 11.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1593) DUF4706 PF15797.5 RUS78193.1 - 2.7 8.5 6.5 32 5.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4706) Cep57_CLD_2 PF14197.6 RUS78193.1 - 4.9 7.3 11.3 3.2 7.9 3.0 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Frataxin_Cyay PF01491.16 RUS78194.1 - 2.4e-35 120.9 0.0 4.4e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Frataxin-like domain Gelsolin PF00626.22 RUS78195.1 - 2.1e-16 59.6 0.1 6.7e-07 29.1 0.0 3.4 3 0 0 3 3 3 2 Gelsolin repeat VHP PF02209.19 RUS78195.1 - 6.2e-10 39.0 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Villin headpiece domain APOBEC3 PF18771.1 RUS78195.1 - 0.048 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 APOBEC3 Gelsolin PF00626.22 RUS78196.1 - 5.3e-11 42.3 0.0 0.014 15.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat AAA PF00004.29 RUS78198.1 - 1.1e-68 229.7 0.0 2.3e-38 131.6 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS78198.1 - 2.8e-23 81.4 0.0 8e-11 41.6 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 RUS78198.1 - 1.2e-14 55.1 1.5 0.00057 20.3 0.1 3.9 2 2 1 3 3 3 3 AAA ATPase domain TIP49 PF06068.13 RUS78198.1 - 2.6e-09 36.8 0.1 0.00052 19.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 RUS78198.1 - 5.3e-09 36.0 0.0 0.017 14.9 0.0 3.6 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RUS78198.1 - 1.9e-08 34.4 0.0 0.011 15.7 0.0 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RUS78198.1 - 4.3e-07 30.2 0.0 0.0039 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RUS78198.1 - 1.9e-06 28.1 0.0 0.0094 16.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS78198.1 - 3.4e-06 27.4 0.3 0.019 15.3 0.0 3.6 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RUS78198.1 - 3.8e-06 27.0 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 RUS78198.1 - 9.2e-06 25.6 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 RUS78198.1 - 1e-05 26.1 0.0 0.0027 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RUS78198.1 - 1.1e-05 25.8 0.0 0.064 13.7 0.0 2.9 2 1 1 3 3 3 2 RNA helicase Vps4_C PF09336.10 RUS78198.1 - 2.4e-05 24.2 0.1 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TsaE PF02367.17 RUS78198.1 - 6.8e-05 22.9 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RUS78198.1 - 0.00011 21.5 0.0 0.35 10.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 RUS78198.1 - 0.00018 21.8 0.1 0.066 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 RUS78198.1 - 0.00027 20.9 0.0 1.9 8.4 0.0 3.7 3 1 1 4 4 4 1 NTPase Rad17 PF03215.15 RUS78198.1 - 0.0004 20.4 1.5 0.38 10.7 0.1 2.8 2 2 0 2 2 2 2 Rad17 P-loop domain AAA_24 PF13479.6 RUS78198.1 - 0.00041 20.1 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RUS78198.1 - 0.00043 20.8 0.1 1 9.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 RUS78198.1 - 0.00053 19.6 0.3 0.85 9.2 0.0 3.1 2 1 1 3 3 3 1 AAA domain Hydin_ADK PF17213.3 RUS78198.1 - 0.00056 20.3 0.3 0.0052 17.1 0.0 2.6 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 RUS78198.1 - 0.00061 19.2 0.6 0.69 9.3 0.1 2.9 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 RUS78198.1 - 0.00061 19.7 0.0 0.91 9.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 RUS78198.1 - 0.00086 19.2 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RUS78198.1 - 0.0011 18.8 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 RUS78198.1 - 0.0013 18.6 0.1 0.96 9.3 0.0 3.5 4 0 0 4 4 3 1 NACHT domain AAA_7 PF12775.7 RUS78198.1 - 0.0026 17.3 0.0 2.9 7.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region CPT PF07931.12 RUS78198.1 - 0.0042 17.0 0.0 0.074 12.9 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 RUS78198.1 - 0.0065 16.2 0.1 0.85 9.4 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 RUS78198.1 - 0.007 16.3 0.0 2.7 7.9 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 RUS78198.1 - 0.01 15.0 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 RUS78198.1 - 0.01 15.9 0.1 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.6 RUS78198.1 - 0.014 15.1 0.3 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RUS78198.1 - 0.029 14.1 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 RUS78198.1 - 0.049 14.1 0.1 11 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 RUS78198.1 - 0.055 12.7 0.1 0.81 8.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 RUS78198.1 - 0.077 12.4 0.0 8.6 5.7 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 RUS78198.1 - 0.11 12.7 0.0 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 RUS78198.1 - 0.13 12.6 0.2 34 4.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ferric_reduct PF01794.19 RUS78199.1 - 0.00049 20.2 0.0 0.00068 19.8 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component RIFIN PF02009.16 RUS78199.1 - 0.00083 19.3 0.1 0.001 19.0 0.1 1.1 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 RUS78199.1 - 0.019 15.3 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) ABG_transport PF03806.13 RUS78199.1 - 0.028 12.7 0.0 0.03 12.5 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family Protocadherin PF08374.11 RUS78199.1 - 0.057 13.4 0.4 0.084 12.8 0.4 1.2 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 RUS78199.1 - 0.1 12.5 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 RUS78199.1 - 0.11 13.4 1.8 0.11 13.4 1.8 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ldl_recept_a PF00057.18 RUS78200.1 - 1.5e-05 25.1 9.5 3.1e-05 24.1 9.5 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PKD PF00801.20 RUS78200.1 - 0.019 14.8 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 PKD domain Sdh_cyt PF01127.22 RUS78201.1 - 6.8e-12 45.5 1.8 7.7e-08 32.4 0.1 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 RUS78202.1 - 4.4e-20 71.9 1.7 6e-20 71.5 1.7 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PATR PF12951.7 RUS78202.1 - 0.027 14.6 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 Passenger-associated-transport-repeat ATP-synt_ab PF00006.25 RUS78203.1 - 6.7e-36 124.0 0.0 9.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rieske_3 PF18465.1 RUS78204.1 - 1.3 9.3 3.9 0.59 10.4 0.2 2.4 2 0 0 2 2 2 0 Rieske 3Fe-4S BAG6 PF12057.8 RUS78205.1 - 0.0098 15.6 0.2 0.13 12.0 0.0 2.2 2 1 0 2 2 2 1 BCL2-associated athanogene 6 YdaT_toxin PF06254.11 RUS78205.1 - 0.02 15.5 2.5 40 4.9 0.0 4.2 1 1 3 4 4 4 0 Putative bacterial toxin ydaT Gmx_para_CXXCG PF09535.10 RUS78206.1 - 0.046 13.0 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) HMG_box PF00505.19 RUS78207.1 - 1.3e-17 64.0 1.7 2.2e-17 63.2 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4819 PF16090.5 RUS78207.1 - 3e-17 62.5 0.0 7.3e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4819) HMG_box_2 PF09011.10 RUS78207.1 - 1.9e-07 31.6 0.5 4.5e-07 30.4 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain DUF4587 PF15248.6 RUS78207.1 - 1.4 9.8 6.1 0.44 11.4 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Fibrinogen_C PF00147.18 RUS78208.1 - 8.3e-56 189.2 6.4 1.4e-55 188.5 6.4 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF241 PF03087.14 RUS78208.1 - 0.013 15.4 2.0 0.013 15.4 0.1 1.8 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Hemagglutinin PF00509.18 RUS78208.1 - 0.013 14.0 0.3 0.019 13.4 0.3 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF1394 PF07159.12 RUS78208.1 - 0.019 14.2 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Baculo_PEP_C PF04513.12 RUS78208.1 - 0.092 12.8 0.8 0.32 11.0 0.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 RUS78208.1 - 0.097 13.0 1.4 0.15 12.4 1.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_U30 PF04523.13 RUS78208.1 - 0.13 10.1 0.6 0.18 9.7 0.6 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FlaC_arch PF05377.11 RUS78208.1 - 0.17 12.3 2.2 0.68 10.4 0.4 2.5 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 RUS78208.1 - 0.18 11.8 1.7 0.9 9.5 0.1 2.3 1 1 0 2 2 2 0 Prefoldin subunit ApoO PF09769.9 RUS78208.1 - 0.2 11.6 0.1 2.7 8.0 0.0 2.1 1 1 1 2 2 2 0 Apolipoprotein O HSBP1 PF06825.12 RUS78208.1 - 6.2 6.8 8.5 0.63 9.9 2.7 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 UFC1 PF08694.11 RUS78209.1 - 9.1e-87 288.5 0.1 1e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SLATT_5 PF18160.1 RUS78209.1 - 0.037 13.3 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 UQ_con PF00179.26 RUS78209.1 - 0.044 13.4 0.1 0.077 12.6 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS78209.1 - 0.09 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain CKS PF01111.19 RUS78210.1 - 1.7e-37 127.5 0.3 3.9e-37 126.4 0.3 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ubiquitin PF00240.23 RUS78210.1 - 3.5e-07 29.9 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS78210.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS78210.1 - 0.04 14.4 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Sortilin-Vps10 PF15902.5 RUS78212.1 - 1.6e-37 129.3 0.3 2.1e-37 129.0 0.3 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 RUS78212.1 - 0.054 13.6 2.9 0.067 13.3 0.0 2.8 4 0 0 4 4 4 0 BNR-Asp box repeat Ldl_recept_a PF00057.18 RUS78213.1 - 2e-78 258.3 174.9 3.3e-11 43.2 11.1 10.7 10 0 0 10 10 10 9 Low-density lipoprotein receptor domain class A Sortilin_C PF15901.5 RUS78213.1 - 1.4e-38 132.9 4.8 1.4e-38 132.9 4.8 5.4 3 1 2 5 5 5 1 Sortilin, neurotensin receptor 3, C-terminal Sortilin-Vps10 PF15902.5 RUS78213.1 - 4.6e-28 98.2 0.0 6.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 RUS78213.1 - 0.85 9.9 4.6 5.2 7.5 0.7 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat fn3 PF00041.21 RUS78214.1 - 4.4e-22 78.2 12.3 4.1e-07 30.2 0.4 6.5 6 0 0 6 6 6 4 Fibronectin type III domain Ldl_recept_a PF00057.18 RUS78214.1 - 0.0049 17.0 10.1 0.0096 16.1 10.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF11 PF01345.18 RUS78214.1 - 0.056 13.8 1.6 8.2 6.8 0.0 3.8 2 2 1 3 3 3 0 Domain of unknown function DUF11 RGM_N PF06535.12 RUS78215.1 - 0.3 11.3 6.7 2.3 8.4 5.2 2.1 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Glyco_transf_10 PF00852.19 RUS78216.1 - 4.6e-45 153.5 0.5 4.6e-45 153.5 0.5 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS78216.1 - 3.3e-15 56.5 0.0 3.3e-15 56.5 0.0 2.6 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Papilloma_E5A PF05776.12 RUS78218.1 - 7.6 7.0 16.9 17 5.9 3.0 3.1 1 1 1 2 2 2 0 Papillomavirus E5A protein Defensin_2 PF01097.18 RUS78219.1 - 0.28 11.2 16.8 66 3.6 0.2 7.1 5 0 0 5 5 5 0 Arthropod defensin Oxidored_molyb PF00174.19 RUS78220.1 - 1.8e-55 187.2 0.0 2.5e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 RUS78220.1 - 1.8e-39 134.9 0.2 6.2e-39 133.2 0.1 1.9 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 RUS78220.1 - 2.9e-12 46.6 0.0 5.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 RUS78220.1 - 0.059 13.4 0.1 0.29 11.3 0.1 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat CH PF00307.31 RUS78221.1 - 1.8e-20 73.1 0.1 7.1e-17 61.6 0.0 2.2 1 1 1 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS78221.1 - 4.2e-05 23.3 0.0 0.00024 20.9 0.0 2.3 3 0 0 3 3 3 1 CAMSAP CH domain Holin_SPP1 PF04688.13 RUS78221.1 - 0.00015 21.9 0.6 0.84 9.9 0.0 2.8 3 0 0 3 3 3 2 SPP1 phage holin CH_2 PF06294.11 RUS78221.1 - 0.06 13.5 0.1 0.19 11.9 0.0 1.8 2 1 0 2 2 2 0 CH-like domain in sperm protein AmiS_UreI PF02293.15 RUS78221.1 - 0.074 13.1 0.4 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 AmiS/UreI family transporter DUF4054 PF13262.6 RUS78221.1 - 0.76 9.8 3.8 3.2 7.8 0.2 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF4054) SOG2 PF10428.9 RUS78223.1 - 0.53 9.4 11.3 0.56 9.3 11.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Tup_N PF08581.10 RUS78224.1 - 0.0077 16.5 3.4 0.052 13.8 2.7 2.2 1 1 1 2 2 2 2 Tup N-terminal ERM PF00769.19 RUS78224.1 - 0.038 13.8 8.9 0.048 13.5 8.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AATF-Che1 PF13339.6 RUS78224.1 - 0.049 14.3 0.8 0.069 13.8 0.8 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor USP8_interact PF08941.10 RUS78224.1 - 0.069 13.0 1.0 0.094 12.5 1.0 1.3 1 0 0 1 1 1 0 USP8 interacting CENP-F_leu_zip PF10473.9 RUS78224.1 - 0.13 12.3 9.1 0.13 12.3 7.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 RUS78224.1 - 0.16 12.1 6.8 3.6 7.8 0.1 2.7 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 RUS78224.1 - 0.27 11.4 14.5 1 9.5 14.5 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 RUS78224.1 - 0.32 11.1 5.0 0.4 10.8 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RUS78224.1 - 0.6 8.9 8.7 0.79 8.6 8.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 RUS78224.1 - 0.71 10.0 9.3 2.8 8.0 9.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 RUS78224.1 - 0.76 9.6 5.1 0.53 10.1 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc24 PF08286.11 RUS78224.1 - 2.6 8.3 7.3 13 6.1 3.1 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PKcGMP_CC PF16808.5 RUS78224.1 - 3.6 7.5 7.1 9.9 6.1 0.2 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DIX PF00778.17 RUS78225.1 - 4.1e-23 81.0 0.0 5.9e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 DIX domain DCB PF16213.5 RUS78226.1 - 1.5e-63 213.7 5.5 2.1e-63 213.2 5.5 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 RUS78226.1 - 6.8e-29 100.8 0.1 3.1e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.25 RUS78227.1 - 2.1e-70 237.1 0.0 2.6e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78227.1 - 1.6e-41 142.3 0.0 2e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS78227.1 - 0.00016 21.1 0.0 0.00044 19.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 RUS78228.1 - 8.2e-17 61.4 0.1 9.9e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78228.1 - 2.7e-11 43.3 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.8 RUS78229.1 - 0.00054 20.3 10.1 0.00054 20.3 10.1 1.4 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 RUS78229.1 - 0.00081 17.8 7.6 0.00082 17.7 7.6 1.1 1 0 0 1 1 1 1 Nop14-like family STAC2_u1 PF16664.5 RUS78229.1 - 0.0094 16.4 7.0 0.015 15.7 7.0 1.2 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PPP4R2 PF09184.11 RUS78229.1 - 0.011 15.4 9.3 0.013 15.1 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 RUS78229.1 - 0.014 15.3 7.7 0.017 14.9 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Astro_capsid_p PF12226.8 RUS78229.1 - 0.022 13.9 6.1 0.028 13.6 6.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein G0-G1_switch_2 PF15103.6 RUS78229.1 - 0.026 14.9 2.5 0.046 14.1 1.7 1.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 TLP-20 PF06088.11 RUS78229.1 - 0.047 13.6 0.7 0.06 13.2 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 RUS78229.1 - 0.063 13.5 3.6 0.099 12.8 2.9 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 RUS78229.1 - 0.092 12.5 2.4 0.12 12.1 2.4 1.2 1 0 0 1 1 1 0 Connexin Nucleo_P87 PF07267.11 RUS78229.1 - 0.17 10.7 4.1 0.18 10.6 4.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TRAP_alpha PF03896.16 RUS78229.1 - 0.17 11.0 6.1 0.24 10.6 6.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.14 RUS78229.1 - 0.22 12.0 28.7 0.36 11.3 28.7 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.12 RUS78229.1 - 0.36 10.1 14.9 0.71 9.1 14.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 RUS78229.1 - 0.38 9.7 2.3 0.39 9.6 2.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 RUS78229.1 - 0.39 9.7 19.3 0.5 9.3 19.3 1.1 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 RUS78229.1 - 0.42 8.5 1.5 0.51 8.2 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CobT PF06213.12 RUS78229.1 - 0.54 9.6 15.0 0.85 9.0 15.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 RUS78229.1 - 0.55 10.0 12.6 0.89 9.3 12.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 RUS78229.1 - 0.6 8.8 5.7 0.9 8.2 5.7 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RUS78229.1 - 0.65 8.2 16.0 0.83 7.9 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 RUS78229.1 - 0.66 9.9 11.2 0.93 9.4 11.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain eIF3_subunit PF08597.10 RUS78229.1 - 1.1 9.1 18.7 1.7 8.5 18.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PTPRCAP PF15713.5 RUS78229.1 - 1.9 8.8 17.0 2.6 8.3 17.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Cnd2 PF05786.14 RUS78229.1 - 2.1 6.9 13.5 2.6 6.6 13.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PBP1_TM PF14812.6 RUS78229.1 - 2.8 8.4 12.0 5.7 7.4 12.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 RUS78229.1 - 3.7 5.5 21.3 4.9 5.1 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TMEM119 PF15724.5 RUS78229.1 - 3.7 7.5 6.6 6.5 6.7 6.6 1.4 1 0 0 1 1 1 0 TMEM119 family GOLD_2 PF13897.6 RUS78229.1 - 4.4 7.8 8.3 7.2 7.1 8.3 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Merozoite_SPAM PF07133.11 RUS78229.1 - 5 7.1 29.4 7.1 6.6 29.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RPA43_OB PF17875.1 RUS78229.1 - 5.8 7.6 7.9 9.7 6.8 7.9 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PI3K_1B_p101 PF10486.9 RUS78229.1 - 6.9 4.3 8.4 8.6 4.0 8.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 RUS78229.1 - 7.6 5.5 21.3 12 4.9 21.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFB6 PF17110.5 RUS78229.1 - 8.2 6.1 8.2 13 5.5 8.2 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4746 PF15928.5 RUS78229.1 - 9.4 5.6 19.5 14 5.0 19.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase PF00069.25 RUS78230.1 - 2.5e-29 102.5 0.0 2.1e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78230.1 - 6.1e-06 25.7 0.3 9.3e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Amnionless PF14828.6 RUS78231.1 - 0.051 12.4 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless CytochromB561_N PF09786.9 RUS78231.1 - 0.072 12.1 0.0 0.082 11.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal LRR19-TM PF15176.6 RUS78231.1 - 0.16 12.0 1.6 0.44 10.6 1.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Herpes_gE PF02480.16 RUS78231.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Tad PF13400.6 RUS78231.1 - 0.22 11.9 2.1 0.31 11.4 2.1 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Sortilin-Vps10 PF15902.5 RUS78232.1 - 2.7e-45 155.0 0.1 3.7e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 RUS78232.1 - 5.2e-27 95.2 1.9 8.6e-27 94.5 1.9 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 RUS78232.1 - 5.2e-06 25.7 5.1 0.65 10.2 0.5 3.9 3 0 0 3 3 3 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 RUS78233.1 - 1.4e-15 57.0 2.1 1.4e-15 57.0 2.1 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, DUF3270 PF11674.8 RUS78233.1 - 0.28 11.4 2.3 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) ABC_tran PF00005.27 RUS78234.1 - 1.3e-48 165.0 0.0 2.9e-27 95.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RUS78234.1 - 2e-21 76.5 38.9 2.9e-11 43.1 13.2 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 RUS78234.1 - 3e-19 70.0 8.5 4.2e-09 36.6 0.1 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RUS78234.1 - 6e-06 26.2 0.0 0.83 9.3 0.0 3.5 2 1 0 3 3 3 3 AAA ATPase domain SMC_N PF02463.19 RUS78234.1 - 9.5e-06 25.2 0.2 0.19 11.1 0.0 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS78234.1 - 1.7e-05 25.5 0.4 0.024 15.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RUS78234.1 - 9.7e-05 22.2 1.8 2.4 7.9 0.0 5.0 5 0 0 5 5 5 1 IstB-like ATP binding protein DUF4162 PF13732.6 RUS78234.1 - 0.00072 20.2 0.1 0.025 15.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 RUS78234.1 - 0.00078 19.1 2.0 0.36 10.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS78234.1 - 0.0035 17.8 0.2 4.4 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 RUS78234.1 - 0.0051 16.7 0.9 0.43 10.5 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 RUS78234.1 - 0.024 14.5 0.1 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 RUS78234.1 - 0.027 13.9 0.5 3 7.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 RUS78234.1 - 0.056 13.1 0.2 4 7.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 RUS78234.1 - 0.12 11.6 0.0 15 4.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 RUS78234.1 - 0.15 11.6 0.3 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RUS78234.1 - 0.33 11.2 2.2 26 5.1 0.1 3.0 3 1 0 3 3 2 0 AAA domain LSR PF05624.14 RUS78234.1 - 4.5 7.3 8.8 18 5.5 8.8 2.0 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) MBD PF01429.19 RUS78236.1 - 2.6e-10 39.8 0.0 5.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain HhH-GPD PF00730.25 RUS78236.1 - 0.011 16.2 0.0 0.22 12.0 0.0 2.7 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein AT_hook PF02178.19 RUS78236.1 - 0.042 13.7 22.8 0.47 10.5 2.3 4.2 3 0 0 3 3 3 0 AT hook motif 7tm_1 PF00001.21 RUS78237.1 - 2.9e-15 56.3 5.5 5.4e-15 55.4 5.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.7 RUS78237.1 - 1.8e-11 44.1 14.0 0.00039 20.8 2.3 4.9 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS78237.1 - 1.1e-08 34.7 17.0 2.1e-06 27.4 7.3 3.8 2 1 0 3 3 3 2 Leucine rich repeat Ldl_recept_a PF00057.18 RUS78237.1 - 0.00015 21.9 1.8 0.00034 20.8 1.8 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A 7TM_GPCR_Srsx PF10320.9 RUS78237.1 - 0.0009 18.7 1.5 0.0026 17.2 1.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx LRR_1 PF00560.33 RUS78237.1 - 0.0028 18.0 14.6 29 5.7 0.1 7.2 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 RUS78237.1 - 0.011 15.7 21.1 7.4 6.9 0.5 6.4 6 0 0 6 6 6 0 Leucine Rich repeat PRKCSH-like PF12999.7 RUS78237.1 - 0.33 10.7 2.6 0.56 10.0 2.6 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Ezh2_MCSS PF18600.1 RUS78237.1 - 6 6.6 7.5 0.26 10.9 0.5 2.3 2 0 0 2 2 2 0 MCSS domain Ldl_recept_a PF00057.18 RUS78238.1 - 4.2e-12 46.1 34.4 2.3e-05 24.5 2.5 4.7 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A Lectin_C PF00059.21 RUS78238.1 - 3.1e-06 27.9 1.8 5e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain DUF4397 PF14344.6 RUS78238.1 - 0.046 14.5 0.2 0.09 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) ABC_tran PF00005.27 RUS78239.1 - 1.6e-16 61.1 0.0 3.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RUS78239.1 - 0.00018 20.7 4.1 0.0004 19.6 4.1 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_18 PF13238.6 RUS78239.1 - 0.015 15.8 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RUS78239.1 - 0.068 12.7 0.3 0.49 9.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RUS78239.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 RUS78240.1 - 4.7e-16 59.6 0.0 9.7e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RUS78240.1 - 2.2e-09 36.9 4.2 2.2e-09 36.9 4.2 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein Av_adeno_fibre PF06536.11 RUS78241.1 - 3.7e-05 23.5 27.8 2.6 8.0 1.3 8.6 4 1 2 6 6 6 5 Avian adenovirus fibre, N-terminal 7tm_1 PF00001.21 RUS78242.1 - 6.9e-19 68.2 0.3 9.9e-19 67.7 0.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78242.1 - 1.3e-05 25.0 0.1 1.9e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS78242.1 - 3.2 7.0 9.5 0.11 11.8 2.0 2.1 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 RUS78243.1 - 0.0023 17.3 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CBM_21 PF03370.13 RUS78245.1 - 6.9e-28 97.1 0.1 1.1e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RUS78245.1 - 1.6e-12 47.8 0.2 3.1e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 RUS78245.1 - 0.091 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SLD5_C PF16922.5 RUS78246.1 - 1.2e-15 57.4 0.1 1.2e-15 57.4 0.1 1.9 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 RUS78246.1 - 3.1e-05 24.4 1.8 5.8e-05 23.5 1.8 1.7 1 1 0 1 1 1 1 GINS complex protein Nrap_D5 PF17406.2 RUS78247.1 - 3.4e-47 160.2 1.0 1.8e-45 154.6 0.0 2.6 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 RUS78247.1 - 3.3e-46 157.3 0.0 5.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 RUS78247.1 - 2.9e-41 141.2 0.2 7.4e-41 139.9 0.1 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 RUS78247.1 - 1.2e-36 126.0 0.1 3e-36 124.8 0.1 1.7 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 RUS78247.1 - 9.8e-31 106.6 0.1 3e-30 105.0 0.1 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 RUS78247.1 - 1.7e-22 80.1 0.0 4.1e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 PRELI PF04707.14 RUS78248.1 - 1.6e-47 161.2 0.0 2.2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF4298 PF14131.6 RUS78248.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Spc7 PF08317.11 RUS78249.1 - 3.8e-07 29.3 12.7 6.6e-07 28.5 12.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 RUS78249.1 - 0.00046 20.2 8.9 0.00046 20.2 8.9 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.10 RUS78249.1 - 0.042 14.1 9.6 0.23 11.8 2.9 3.3 3 0 0 3 3 3 0 Tup N-terminal SPATA19 PF15212.6 RUS78249.1 - 0.078 13.2 1.7 0.68 10.2 0.2 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial RPN5_C PF18098.1 RUS78249.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.9 3 0 0 3 3 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain PilJ PF13675.6 RUS78249.1 - 0.15 12.1 1.7 0.61 10.1 0.3 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SRF-TF PF00319.18 RUS78249.1 - 0.17 11.4 0.3 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) H-kinase_dim PF02895.14 RUS78249.1 - 0.26 11.7 5.9 1.9 9.0 5.9 2.5 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Snapin_Pallidin PF14712.6 RUS78249.1 - 0.27 11.7 16.9 0.2 12.1 7.5 2.9 2 1 1 3 3 3 0 Snapin/Pallidin XhlA PF10779.9 RUS78249.1 - 0.57 10.4 9.5 2.3 8.5 2.3 3.1 2 1 1 3 3 3 0 Haemolysin XhlA Fez1 PF06818.15 RUS78249.1 - 2.3 8.6 15.5 0.12 12.8 8.3 2.0 1 1 1 2 2 2 0 Fez1 UPF0184 PF03670.13 RUS78249.1 - 3.3 8.2 6.1 1.6 9.2 0.4 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.9 RUS78249.1 - 3.4 6.7 20.8 0.35 9.9 12.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 RUS78249.1 - 3.7 7.9 8.6 0.57 10.5 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 RUS78249.1 - 8.3 6.5 10.0 19 5.3 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 RUS78249.1 - 8.6 6.4 17.6 1.4 8.9 1.4 2.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-C2H2_4 PF13894.6 RUS78250.1 - 2.2e-23 80.9 42.7 0.00039 21.0 1.5 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS78250.1 - 1.6e-21 75.5 46.8 2.5e-05 24.5 0.6 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78250.1 - 3.6e-18 65.1 49.9 4.4e-05 23.7 0.4 7.4 8 0 0 8 8 8 5 Zinc-finger double domain zf-met PF12874.7 RUS78250.1 - 9.3e-13 48.1 29.9 0.022 15.2 2.3 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS78250.1 - 4.3e-12 46.0 25.5 0.009 16.3 2.0 6.1 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS78250.1 - 1.5e-08 34.2 32.5 0.0071 16.1 4.5 5.7 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS78250.1 - 2.1e-08 33.9 33.5 0.0001 22.2 1.5 6.5 5 1 1 6 6 6 4 C2H2-type zinc finger BolA PF01722.18 RUS78250.1 - 0.0084 16.4 1.5 0.15 12.4 0.4 3.2 2 1 0 2 2 2 1 BolA-like protein zf-C2H2_3rep PF18868.1 RUS78250.1 - 0.49 11.1 23.6 14 6.4 1.7 4.3 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 RUS78250.1 - 5.4 7.1 26.2 0.15 12.1 1.4 5.2 3 2 0 3 3 3 0 BED zinc finger PriA_CRR PF18319.1 RUS78250.1 - 7.7 6.6 17.6 4.3 7.4 0.2 5.0 5 0 0 5 5 5 0 PriA DNA helicase Cys-rich region (CRR) domain EF-hand_1 PF00036.32 RUS78251.1 - 3.6e-17 60.6 0.0 6.1e-06 25.4 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS78251.1 - 9.8e-17 61.2 3.8 9.5e-14 51.6 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS78251.1 - 3.4e-15 54.6 0.8 9e-05 22.1 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RUS78251.1 - 2.5e-10 39.4 0.0 0.00011 21.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RUS78251.1 - 8.1e-08 32.0 2.7 7.7e-05 22.5 0.2 3.7 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_11 PF08976.11 RUS78251.1 - 0.012 16.4 0.1 0.11 13.4 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 RUS78251.1 - 0.04 14.3 0.7 0.43 10.9 0.2 2.4 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS78251.1 - 0.069 13.5 0.2 0.64 10.4 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 RUS78251.1 - 0.08 13.1 0.0 1.5 9.1 0.0 2.2 1 1 1 2 2 2 0 Dockerin type I domain DUF5009 PF16401.5 RUS78252.1 - 0.00022 20.8 3.3 0.00022 20.8 3.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) GWT1 PF06423.12 RUS78252.1 - 0.74 9.9 6.9 0.14 12.3 2.2 2.2 2 1 0 2 2 2 0 GWT1 Trypan_PARP PF05887.11 RUS78254.1 - 0.4 10.6 7.2 0.76 9.8 7.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRM_1 PF00076.22 RUS78255.1 - 2.9e-43 145.5 1.1 2.4e-20 72.1 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS78255.1 - 4.3e-05 23.5 0.1 0.6 10.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif Ribosomal_S30AE PF02482.19 RUS78255.1 - 0.017 15.9 0.1 0.055 14.3 0.1 1.8 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein RRM_occluded PF16842.5 RUS78255.1 - 0.048 13.5 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif SIX1_SD PF16878.5 RUS78256.1 - 1e-46 158.0 0.1 2.6e-45 153.5 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RUS78256.1 - 4.9e-15 55.1 0.5 1.1e-14 53.9 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS78256.1 - 1.2e-09 37.8 0.6 2.3e-09 37.0 0.6 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 RUS78256.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Macoilin PF09726.9 RUS78256.1 - 0.033 12.7 4.8 0.046 12.3 4.8 1.2 1 0 0 1 1 1 0 Macoilin family TPR_15 PF13429.6 RUS78256.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat 2HCT PF03390.15 RUS78257.1 - 0.0014 17.3 0.7 0.0018 17.0 0.7 1.2 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family Macoilin PF09726.9 RUS78257.1 - 0.0079 14.8 4.6 0.012 14.2 4.6 1.3 1 0 0 1 1 1 1 Macoilin family MMR1 PF08505.10 RUS78257.1 - 0.013 15.9 7.0 0.013 15.9 7.0 1.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein PRC2_HTH_1 PF18118.1 RUS78257.1 - 0.014 16.2 3.7 0.034 15.0 3.7 1.5 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain RIFIN PF02009.16 RUS78257.1 - 0.037 13.9 6.7 0.062 13.2 6.7 1.3 1 0 0 1 1 1 0 Rifin Orthoreo_P10 PF07204.11 RUS78257.1 - 0.059 13.3 0.8 0.14 12.1 0.8 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Pex14_N PF04695.13 RUS78257.1 - 0.091 13.4 7.2 0.21 12.2 7.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 RUS78257.1 - 0.13 11.3 1.7 0.2 10.7 1.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RskA PF10099.9 RUS78257.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Spt20 PF12090.8 RUS78257.1 - 0.27 10.8 17.9 0.46 10.1 17.9 1.3 1 0 0 1 1 1 0 Spt20 family Band_3_cyto PF07565.13 RUS78257.1 - 0.83 9.4 8.5 1.6 8.5 8.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Lin-8 PF03353.15 RUS78257.1 - 7.5 6.0 11.3 12 5.3 11.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4175 PF13779.6 RUS78257.1 - 8.2 4.2 15.0 11 3.8 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tctex-1 PF03645.13 RUS78258.1 - 1.6e-22 79.7 0.4 2.1e-22 79.3 0.4 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF2895 PF11444.8 RUS78258.1 - 0.0083 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2895) FtsJ PF01728.19 RUS78259.1 - 9.7e-39 133.3 0.0 1.7e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 RUS78259.1 - 2.2e-12 46.7 6.9 4.6e-12 45.6 6.9 1.5 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 RUS78259.1 - 0.0011 18.9 0.2 0.0023 18.0 0.2 1.6 1 0 0 1 1 1 1 WW domain G-patch_2 PF12656.7 RUS78259.1 - 0.0033 17.5 2.1 0.0079 16.3 2.1 1.6 1 0 0 1 1 1 1 G-patch domain p450 PF00067.22 RUS78260.1 - 2.3e-111 372.8 0.0 2.9e-111 372.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.22 RUS78261.1 - 1.7e-39 135.9 21.1 8.1e-27 94.3 12.0 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter ABC2_membrane_5 PF13346.6 RUS78261.1 - 0.004 16.7 1.1 2.2 7.8 0.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein CSN8_PSD8_EIF3K PF10075.9 RUS78262.1 - 4.1e-32 111.1 0.1 6.6e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family NRDE-2 PF08424.10 RUS78263.1 - 9.8e-89 297.7 11.6 1.5e-88 297.0 8.1 2.8 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference DUF4372 PF14294.6 RUS78263.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4372) TIP49_C PF17856.1 RUS78264.1 - 1.4e-06 28.4 13.0 12 6.2 0.1 7.1 1 1 9 10 10 10 8 TIP49 AAA-lid domain MU2_FHA PF18221.1 RUS78264.1 - 0.0086 16.1 5.3 24 5.0 0.1 4.4 1 1 5 6 6 6 3 Mutator 2 Fork head associated domain Myosin_TH1 PF06017.13 RUS78264.1 - 1.5 8.4 4.3 30 4.2 2.1 2.8 1 1 1 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding Motilin_assoc PF04643.12 RUS78264.1 - 3.9 7.4 22.4 1.5e+02 2.3 0.3 8.8 2 1 6 9 9 9 0 Motilin/ghrelin-associated peptide SNAP-25 PF00835.19 RUS78265.1 - 2.3e-23 82.2 1.5 5.2e-23 81.1 1.5 1.6 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 RUS78265.1 - 0.0001 22.3 4.9 0.021 14.7 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 RUS78265.1 - 0.0022 18.2 7.6 0.24 11.7 0.7 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.11 RUS78265.1 - 0.0084 15.0 6.9 0.096 11.6 0.7 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 RUS78265.1 - 0.026 15.0 12.5 0.24 11.9 0.9 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 RUS78265.1 - 0.044 14.3 6.9 0.8 10.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 SNARE PF05739.19 RUS78265.1 - 0.066 13.2 9.1 0.36 10.8 0.8 2.9 3 0 0 3 3 2 0 SNARE domain RasGAP_C PF03836.15 RUS78265.1 - 0.15 12.2 3.5 1.7 8.8 1.3 2.3 2 1 0 2 2 2 0 RasGAP C-terminus Phage_GP20 PF06810.11 RUS78265.1 - 0.18 11.6 4.6 1.7 8.4 0.1 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 RmuC PF02646.16 RUS78265.1 - 0.31 10.1 6.5 0.17 11.0 1.0 2.3 2 1 0 2 2 2 0 RmuC family DUF948 PF06103.11 RUS78265.1 - 0.33 11.2 7.5 1.4 9.2 0.5 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 RUS78265.1 - 0.35 10.9 12.3 0.29 11.2 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 RUS78265.1 - 0.37 10.9 3.4 5.7 7.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.15 RUS78265.1 - 0.37 10.6 8.8 0.11 12.2 0.7 2.7 3 0 0 3 3 3 0 Septum formation initiator Laminin_II PF06009.12 RUS78265.1 - 0.43 10.6 7.0 3.2 7.8 1.3 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF4140 PF13600.6 RUS78265.1 - 0.47 10.9 2.4 23 5.5 0.0 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 RUS78265.1 - 0.51 10.7 10.7 2.9 8.2 0.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Duo1 PF08651.10 RUS78265.1 - 0.83 9.5 7.9 6.6 6.6 0.7 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 Golgin_A5 PF09787.9 RUS78265.1 - 1.2 8.6 12.2 0.65 9.4 4.2 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 XhlA PF10779.9 RUS78265.1 - 1.3 9.2 11.2 4.6 7.5 1.0 3.5 2 2 1 3 3 3 0 Haemolysin XhlA TMPIT PF07851.13 RUS78265.1 - 3 7.0 6.5 7 5.8 1.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein KxDL PF10241.9 RUS78265.1 - 3.3 8.1 8.4 2.6 8.4 0.4 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 RUS78265.1 - 6.8 7.4 11.7 7.3 7.3 0.5 2.9 3 0 0 3 3 3 0 SlyX SRTM1 PF15872.5 RUS78266.1 - 0.021 15.0 0.1 0.065 13.4 0.1 1.8 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 DUF3169 PF11368.8 RUS78266.1 - 0.38 10.2 7.5 26 4.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) PI3K_P85_iSH2 PF16454.5 RUS78267.1 - 0.32 10.6 1.4 1.6 8.3 1.4 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain C2 PF00168.30 RUS78268.1 - 2.2e-11 44.0 0.1 2.6e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 C2 domain 7tm_1 PF00001.21 RUS78270.1 - 4e-23 82.1 12.3 5.1e-23 81.7 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78270.1 - 0.0085 15.8 9.6 0.0085 15.8 9.6 2.2 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx adh_short_C2 PF13561.6 RUS78271.1 - 5.5e-47 160.3 0.1 8.4e-47 159.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS78271.1 - 1.6e-34 119.1 0.1 2.7e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS78271.1 - 4.9e-08 33.1 0.1 7.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 RUS78271.1 - 0.0019 18.7 0.1 0.004 17.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 RUS78271.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 RUS78271.1 - 0.028 14.7 0.1 0.08 13.2 0.0 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 RUS78271.1 - 0.058 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 RUS78271.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS78271.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain BolA PF01722.18 RUS78272.1 - 1.7e-13 50.6 0.0 3.4e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein FH2 PF02181.23 RUS78274.1 - 8.9e-56 189.6 3.1 8.9e-56 189.6 3.1 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain BLOC1_2 PF10046.9 RUS78274.1 - 5.3 7.4 6.5 12 6.3 0.7 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 RUS78274.1 - 5.5 7.5 7.5 4.8 7.7 0.7 3.7 3 0 0 3 3 3 0 Cell division protein ZapB Iwr1 PF08574.10 RUS78278.1 - 2.2e-09 38.2 11.9 2.2e-09 38.2 11.9 3.5 3 2 0 3 3 3 1 Transcription factor Iwr1 Inositol_P PF00459.25 RUS78279.1 - 9.1e-43 146.7 3.2 3.4e-23 82.5 1.1 2.0 1 1 1 2 2 2 2 Inositol monophosphatase family SipA_VBS PF17985.1 RUS78279.1 - 0.0073 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 SipA vinculin binding site Ank_2 PF12796.7 RUS78280.1 - 3.3e-25 88.5 0.2 1.6e-14 54.3 0.1 3.2 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78280.1 - 1.5e-17 63.7 2.1 3.1e-10 40.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 RUS78280.1 - 2.3e-16 59.8 17.0 4.9e-06 26.7 0.6 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat Ank_5 PF13857.6 RUS78280.1 - 4.8e-15 55.4 4.7 3.8e-07 30.3 0.1 4.0 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78280.1 - 5.2e-13 47.9 1.4 0.00012 22.2 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RUS78280.1 - 9.9e-12 44.8 4.1 0.0016 18.8 0.2 4.7 4 0 0 4 4 4 3 Ankyrin repeat TPR_7 PF13176.6 RUS78280.1 - 4.4e-11 42.0 15.5 0.0017 18.2 0.8 7.0 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 RUS78280.1 - 4.7e-11 42.0 22.4 0.037 13.9 0.3 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS78280.1 - 6.6e-10 38.3 28.2 0.023 14.8 0.5 9.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS78280.1 - 1.8e-09 37.1 25.0 0.029 14.6 0.2 8.4 9 0 0 9 9 8 3 Tetratricopeptide repeat LRR_6 PF13516.6 RUS78280.1 - 1.9e-07 30.6 26.9 0.00045 20.0 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 RUS78280.1 - 1.5e-06 28.4 21.9 0.0062 16.9 1.9 5.8 6 0 0 6 6 5 3 Leucine Rich repeats (2 copies) TPR_10 PF13374.6 RUS78280.1 - 0.00089 19.1 5.1 36 4.4 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS78280.1 - 0.0018 19.0 6.0 15 6.7 0.3 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS78280.1 - 0.012 16.3 2.1 0.08 13.6 1.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS78280.1 - 0.051 12.9 6.0 0.18 11.2 2.3 3.2 1 1 2 3 3 3 0 MalT-like TPR region TPR_15 PF13429.6 RUS78280.1 - 0.092 11.9 6.1 0.028 13.7 1.6 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 RUS78280.1 - 0.12 12.2 20.2 1.2 9.0 1.6 5.7 5 1 0 5 5 5 0 Leucine rich repeat TPR_17 PF13431.6 RUS78280.1 - 0.13 12.6 0.3 1.1e+02 3.6 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 RUS78280.1 - 0.15 12.1 3.1 1.7 8.7 0.1 3.6 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) XRN_M PF17846.1 RUS78280.1 - 0.54 9.1 6.0 10 4.9 1.4 3.0 2 0 0 2 2 2 0 Xrn1 helical domain K1377 PF15352.6 RUS78281.1 - 3.6e-21 75.2 19.6 2.1e-16 59.5 0.8 5.5 3 1 3 6 6 6 3 Susceptibility to monomelic amyotrophy DUF3240 PF11582.8 RUS78282.1 - 8 6.7 7.0 0.57 10.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) Gemini_AL3 PF01407.17 RUS78283.1 - 0.14 12.0 3.1 3 7.7 0.7 2.7 1 1 2 3 3 3 0 Geminivirus AL3 protein LANC_like PF05147.13 RUS78284.1 - 1.4e-76 257.3 0.0 1.8e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 RUS78284.1 - 0.15 10.5 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Macoilin PF09726.9 RUS78285.1 - 6.4e-250 831.4 18.9 8e-250 831.0 18.9 1.0 1 0 0 1 1 1 1 Macoilin family CENP-F_leu_zip PF10473.9 RUS78285.1 - 0.0028 17.7 45.4 0.009 16.0 17.7 2.5 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 RUS78285.1 - 4.3 6.6 51.0 0.48 9.8 23.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 RUS78285.1 - 4.6 6.5 39.3 0.16 11.3 17.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Iron_permease PF04120.12 RUS78285.1 - 8 6.3 6.9 36 4.1 6.9 2.1 1 0 0 1 1 1 0 Low affinity iron permease Cpn60_TCP1 PF00118.24 RUS78286.1 - 2e-148 495.1 7.9 2.3e-148 494.9 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MSSP PF03940.13 RUS78287.1 - 0.79 9.4 4.3 0.43 10.2 0.9 2.3 2 0 0 2 2 2 0 Male specific sperm protein Ras PF00071.22 RUS78288.1 - 1.8e-19 69.9 0.0 2.7e-19 69.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS78288.1 - 2e-19 70.0 0.0 1.4e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78288.1 - 3.2e-09 36.5 0.0 7.7e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS78288.1 - 4e-05 23.1 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS78288.1 - 6.5e-05 23.0 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS78288.1 - 0.00089 19.7 0.0 0.0017 18.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 RUS78288.1 - 0.0038 16.3 0.0 0.0092 15.1 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 RUS78288.1 - 0.0093 15.9 0.1 0.04 13.8 0.0 2.0 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 RUS78288.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 RUS78288.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 RUS78288.1 - 0.016 15.0 0.0 0.5 10.1 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 RUS78288.1 - 0.021 15.4 0.1 0.029 14.9 0.1 1.7 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 RUS78288.1 - 0.026 14.5 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.10 RUS78288.1 - 0.046 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RUS78288.1 - 0.071 13.4 0.1 0.3 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS78288.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS78288.1 - 0.085 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 RUS78288.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 RUS78288.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 RUS78288.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain NTP_transf_7 PF07984.12 RUS78290.1 - 2.1e-158 526.7 2.2 2.6e-158 526.4 2.2 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Myb_DNA-bind_6 PF13921.6 RUS78290.1 - 0.046 14.0 0.1 0.68 10.2 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain PX PF00787.24 RUS78290.1 - 0.1 12.6 0.8 0.3 11.1 0.8 1.8 1 1 0 1 1 1 0 PX domain Transket_pyr PF02779.24 RUS78292.1 - 6.8e-40 136.6 0.0 1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RUS78292.1 - 5.6e-33 113.5 0.0 1.2e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pkinase_Tyr PF07714.17 RUS78293.1 - 6.8e-60 202.5 0.2 1.2e-59 201.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 RUS78293.1 - 4.8e-55 186.7 0.0 8e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RUS78293.1 - 0.00079 19.4 0.0 0.017 15.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RUS78293.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 RUS78294.1 - 3.4e-25 88.8 17.7 5e-25 88.3 17.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS78294.1 - 4.1e-14 52.3 22.2 4.1e-14 52.3 22.2 2.5 3 1 0 3 3 3 1 Major Facilitator Superfamily V-set PF07686.17 RUS78295.1 - 0.0007 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 RUS78295.1 - 0.00086 19.9 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS78295.1 - 0.0047 17.0 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RUS78295.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain wnt PF00110.19 RUS78297.1 - 1.7e-119 399.0 22.9 2e-119 398.8 22.9 1.0 1 0 0 1 1 1 1 wnt family RhoGAP PF00620.27 RUS78298.1 - 9.4e-41 139.2 0.8 9.4e-41 139.2 0.8 2.2 2 0 0 2 2 2 1 RhoGAP domain Zip PF02535.22 RUS78298.1 - 0.0065 15.7 2.0 0.012 14.9 2.0 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter SlyX PF04102.12 RUS78298.1 - 1.8 9.2 17.6 1.6 9.4 0.3 4.3 3 1 0 3 3 3 0 SlyX OATP PF03137.20 RUS78298.1 - 2.7 6.2 5.7 5 5.3 5.7 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Exo_endo_phos PF03372.23 RUS78299.1 - 3.6e-11 43.0 0.0 8.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS78299.1 - 0.011 15.5 0.3 0.065 13.1 0.0 2.2 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase PORR PF11955.8 RUS78300.1 - 0.0049 15.9 0.0 7.4 5.4 0.0 3.0 3 0 0 3 3 3 3 Plant organelle RNA recognition domain DUF4743 PF15916.5 RUS78300.1 - 0.042 13.8 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4743) 7tm_1 PF00001.21 RUS78301.1 - 4.7e-34 117.9 18.1 5.9e-34 117.6 18.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HMG_box_2 PF09011.10 RUS78302.1 - 8.2e-33 112.8 11.2 1.6e-20 73.5 6.4 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 RUS78302.1 - 1.2e-28 99.3 12.9 8.4e-14 51.7 0.4 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.6 RUS78302.1 - 0.00013 21.9 2.9 0.012 15.5 0.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 DUF3245 PF11595.8 RUS78302.1 - 0.0019 18.7 2.9 0.0019 18.7 2.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) ANAPC15 PF15243.6 RUS78302.1 - 1.1 9.7 16.3 5.2 7.6 13.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.11 RUS78302.1 - 3.1 7.8 10.4 0.43 10.6 5.9 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.6 RUS78302.1 - 5.2 7.5 25.6 3.8 7.9 16.1 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RUS78302.1 - 6 6.1 17.2 0.4 10.0 12.2 1.5 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.9 RUS78302.1 - 9.4 5.2 21.2 0.36 9.9 13.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RA PF00788.23 RUS78303.1 - 1.4e-14 54.5 0.6 2.4e-14 53.7 0.3 1.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 RUS78303.1 - 0.001 18.9 8.3 0.0015 18.4 8.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 RUS78303.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Ras-binding domain of Byr2 MmgE_PrpD PF03972.14 RUS78305.1 - 0.11 11.0 1.0 0.17 10.4 1.0 1.3 1 0 0 1 1 1 0 MmgE/PrpD family AT_hook PF02178.19 RUS78305.1 - 0.18 11.8 8.8 0.25 11.3 1.6 3.4 2 0 0 2 2 2 0 AT hook motif IF2_assoc PF08364.11 RUS78305.1 - 6.5 7.1 17.0 4.8 7.5 6.3 4.2 3 1 0 3 3 3 0 Bacterial translation initiation factor IF-2 associated region Endonuclease_7 PF02945.15 RUS78307.1 - 0.018 15.0 0.5 0.024 14.6 0.5 1.2 1 0 0 1 1 1 0 Recombination endonuclease VII ThiC_Rad_SAM PF01964.18 RUS78307.1 - 0.061 12.1 0.9 0.12 11.1 0.7 1.5 1 1 1 2 2 2 0 Radical SAM ThiC family BRE1 PF08647.11 RUS78309.1 - 0.00091 19.2 11.6 0.00091 19.2 11.6 9.6 5 3 3 9 9 9 4 BRE1 E3 ubiquitin ligase PKcGMP_CC PF16808.5 RUS78309.1 - 0.0033 17.2 0.4 0.0033 17.2 0.4 6.8 8 0 0 8 8 8 2 Coiled-coil N-terminus of cGMP-dependent protein kinase HAMP PF00672.25 RUS78309.1 - 0.12 12.8 2.8 24 5.4 0.0 4.2 3 0 0 3 3 3 0 HAMP domain HLH PF00010.26 RUS78310.1 - 1.7e-15 56.7 0.3 1.7e-15 56.7 0.3 2.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Rootletin PF15035.6 RUS78310.1 - 0.00064 19.8 2.6 0.00064 19.8 2.6 3.2 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion CortBP2 PF09727.9 RUS78310.1 - 0.051 13.5 0.4 0.051 13.5 0.4 4.1 3 1 1 4 4 4 0 Cortactin-binding protein-2 SCHIP-1 PF10148.9 RUS78311.1 - 0.081 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Helicase_C_2 PF13307.6 RUS78312.1 - 5.9e-45 153.5 0.0 8.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain Homeobox_KN PF05920.11 RUS78313.1 - 2.5e-12 46.5 0.8 2.5e-12 46.5 0.8 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 RUS78313.1 - 6.7e-08 32.3 1.3 1.8e-07 30.9 1.3 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 RUS78313.1 - 0.019 14.4 0.1 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Abhydrolase_2 PF02230.16 RUS78314.1 - 6.8e-73 245.1 0.0 8e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 RUS78314.1 - 7.5e-08 33.2 0.0 9.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS78314.1 - 2.1e-07 30.5 0.1 0.0089 15.3 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS78314.1 - 1.1e-06 28.6 1.4 0.029 14.0 0.2 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS78314.1 - 2.3e-05 24.0 0.2 0.0026 17.2 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 RUS78314.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 RUS78314.1 - 0.00036 20.3 0.0 0.0033 17.1 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 RUS78314.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 RUS78314.1 - 0.0046 16.6 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.22 RUS78314.1 - 0.011 15.8 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.7 RUS78314.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 RUS78314.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 RUS78314.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase TBP PF00352.21 RUS78315.1 - 9.4e-45 150.5 0.2 1.1e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Adap_comp_sub PF00928.21 RUS78315.1 - 0.062 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family DUF2807 PF10988.8 RUS78315.1 - 0.12 12.2 0.8 3.6 7.3 0.0 2.6 3 0 0 3 3 3 0 Putative auto-transporter adhesin, head GIN domain F-box-like PF12937.7 RUS78316.1 - 2.5e-07 30.5 0.3 1.5e-06 27.9 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 RUS78316.1 - 4.9e-05 23.1 0.2 0.0009 19.1 0.0 2.9 2 1 0 2 2 2 1 F-box domain Elongin_A PF06881.11 RUS78316.1 - 0.0028 18.2 0.1 0.0069 16.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C2H2 PF00096.26 RUS78317.1 - 4.2e-13 49.0 45.8 0.00072 19.9 0.7 7.1 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78317.1 - 2e-10 40.6 24.2 2.9e-05 24.3 0.2 6.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 RUS78317.1 - 4.2e-05 23.8 6.0 0.069 13.5 1.2 3.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 RUS78317.1 - 0.017 15.9 0.3 0.017 15.9 0.3 7.4 7 1 0 7 7 7 0 C2H2-type zinc finger PDZ PF00595.24 RUS78318.1 - 3e-15 56.3 0.0 4.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS78318.1 - 7e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS78318.1 - 3.5e-06 27.2 0.0 5.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LRR_9 PF14580.6 RUS78319.1 - 1e-14 54.5 1.3 1.8e-14 53.6 1.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RUS78319.1 - 1.7e-08 34.6 9.3 0.00024 21.4 1.4 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS78319.1 - 7.6e-05 22.4 7.8 0.00028 20.6 3.1 3.3 1 1 3 4 4 4 3 Leucine rich repeat Ant_C PF05586.11 RUS78319.1 - 0.085 13.5 2.1 0.17 12.5 0.2 2.4 1 1 1 2 2 2 0 Anthrax receptor C-terminus region Chal_sti_synt_N PF00195.19 RUS78320.1 - 0.046 13.1 0.5 0.054 12.9 0.5 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain CedA PF10729.9 RUS78320.1 - 0.12 12.2 0.1 0.6 10.0 0.0 1.9 1 1 1 2 2 2 0 Cell division activator CedA Pkinase PF00069.25 RUS78321.1 - 3e-61 207.1 0.0 3e-61 207.1 0.0 3.9 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78321.1 - 1.6e-29 103.0 0.0 1.6e-29 103.0 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.11 RUS78321.1 - 2.2e-15 57.2 13.1 2.2e-15 57.2 13.1 12.7 4 3 7 12 12 12 1 Rho Binding APH PF01636.23 RUS78321.1 - 0.00091 19.2 0.6 0.0041 17.1 0.6 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 RUS78321.1 - 0.0029 18.3 1.4 0.011 16.5 1.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Integrase_H2C2 PF17921.1 RUS78322.1 - 8.5e-13 48.2 0.1 1.7e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS78322.1 - 2.4e-07 30.9 0.0 4.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MPS-4 PF17523.2 RUS78322.1 - 0.0057 16.8 0.4 0.013 15.6 0.2 1.6 2 0 0 2 2 2 1 MinK-related peptide, potassium channel accessory sub-unit protein 4 TMEM107 PF14995.6 RUS78322.1 - 0.077 13.4 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein zf-H2C2 PF09337.10 RUS78322.1 - 0.13 12.5 0.2 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RTC PF01137.21 RUS78323.1 - 9.9e-54 181.9 0.0 1.1e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RUS78323.1 - 4.2e-36 123.6 0.0 6.7e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DDE_3 PF13358.6 RUS78324.1 - 0.0024 17.6 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NAD_binding_1 PF00175.21 RUS78325.1 - 8.2e-15 55.4 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RUS78325.1 - 2.4e-07 31.0 0.0 1.5e-05 25.2 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RUS78325.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Chibby PF14645.6 RUS78325.1 - 0.098 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Chibby family LRR_8 PF13855.6 RUS78327.1 - 1.8e-54 181.3 38.3 8.2e-13 47.9 0.5 8.2 5 2 6 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 RUS78327.1 - 7.1e-31 105.7 29.2 0.0003 21.1 0.0 9.7 4 3 7 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS78327.1 - 1.8e-15 55.1 13.0 1.1 10.1 0.0 12.7 13 0 0 13 13 13 1 Leucine Rich Repeat LRR_5 PF13306.6 RUS78327.1 - 3.7e-11 43.1 0.2 1.1e-09 38.3 0.0 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS78327.1 - 2e-07 30.5 36.0 0.12 12.5 0.1 11.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_9 PF14580.6 RUS78327.1 - 2.8e-05 23.7 8.3 0.22 11.0 0.1 4.2 2 2 1 4 4 4 3 Leucine-rich repeat HLH PF00010.26 RUS78329.1 - 1.4e-15 57.0 0.5 4.3e-15 55.4 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 RUS78329.1 - 0.0022 17.8 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain PMBR PF09373.10 RUS78329.1 - 0.036 14.2 0.2 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Pseudomurein-binding repeat WD40 PF00400.32 RUS78330.1 - 3.1e-09 37.3 2.8 0.2 12.6 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS78330.1 - 0.0011 19.3 0.0 48 4.4 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 RUS78331.1 - 6.4e-16 58.1 0.3 1.3e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF773 PF05600.12 RUS78331.1 - 0.079 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Macoilin PF09726.9 RUS78331.1 - 0.084 11.4 7.7 0.11 11.0 7.7 1.2 1 0 0 1 1 1 0 Macoilin family HTH_51 PF18558.1 RUS78331.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ocular_alb PF02101.15 RUS78331.1 - 0.98 8.3 2.3 1.3 7.9 2.3 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein NST1 PF13945.6 RUS78331.1 - 9.5 6.3 14.5 16 5.6 14.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Pkinase PF00069.25 RUS78332.1 - 3.7e-58 197.0 0.0 9.5e-58 195.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78332.1 - 3.3e-41 141.3 0.1 1.1e-40 139.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.27 RUS78332.1 - 7.7e-09 35.4 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RIO1 PF01163.22 RUS78332.1 - 7.5e-07 28.9 0.1 2e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RUS78332.1 - 9.7e-07 27.9 0.1 6.9e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS78332.1 - 2e-06 27.3 0.5 8.1e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RUS78332.1 - 3.1e-06 26.4 0.9 9.9e-06 24.7 0.3 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 RUS78332.1 - 9.8e-06 25.7 0.0 5.5e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family V-ATPase_H_N PF03224.14 RUS78332.1 - 6.5e-05 22.4 8.2 0.0033 16.8 1.6 2.8 2 1 0 3 3 3 2 V-ATPase subunit H Arm PF00514.23 RUS78332.1 - 0.0004 20.3 12.3 1.4 9.1 0.0 6.1 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Rcd1 PF04078.13 RUS78332.1 - 0.0052 16.1 3.0 0.0073 15.6 0.2 2.6 3 0 0 3 3 3 1 Cell differentiation family, Rcd1-like Phage_TAC_12 PF12363.8 RUS78332.1 - 0.055 13.9 0.0 4.4 7.8 0.0 3.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC zf-H2C2_2 PF13465.6 RUS78336.1 - 1.1e-28 98.3 30.1 3.7e-06 27.1 0.9 8.5 7 1 1 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS78336.1 - 2.1e-19 68.8 53.9 1.1e-05 25.6 3.9 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS78336.1 - 4.2e-15 55.1 50.0 0.023 15.5 2.0 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-Di19 PF05605.12 RUS78336.1 - 2.9e-07 30.7 42.9 0.021 15.1 0.3 5.5 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RUS78336.1 - 1.2e-06 28.1 0.2 1.2e-06 28.1 0.2 6.9 7 0 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS78336.1 - 5.6e-05 23.0 0.8 5.6e-05 23.0 0.8 7.2 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS78336.1 - 0.0005 19.8 1.6 0.0005 19.8 1.6 4.2 6 0 0 6 6 6 1 zinc-finger C2H2-type Trp_repressor PF01371.19 RUS78336.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein AT_hook PF02178.19 RUS78336.1 - 0.27 11.3 58.7 0.16 11.9 0.8 7.2 7 0 0 7 7 7 0 AT hook motif Glyco_transf_54 PF04666.13 RUS78337.1 - 1.8e-94 315.9 0.0 2.5e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region fn3 PF00041.21 RUS78340.1 - 8.5e-54 179.9 6.8 5.1e-19 68.4 0.0 4.0 4 0 0 4 4 4 4 Fibronectin type III domain Tissue_fac PF01108.17 RUS78340.1 - 5.2e-08 32.7 0.5 0.0025 17.6 0.0 3.7 4 0 0 4 4 4 2 Tissue factor Pur_ac_phosph_N PF16656.5 RUS78340.1 - 6.6e-07 29.8 2.6 0.011 16.3 0.0 4.2 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RUS78340.1 - 0.0042 17.4 0.0 0.56 10.6 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2369) Neur_chan_LBD PF02931.23 RUS78341.1 - 3e-46 157.6 0.0 4.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS78341.1 - 2.6e-31 109.5 5.1 3.3e-26 92.8 3.4 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CRAL_TRIO PF00650.20 RUS78342.1 - 5.1e-29 101.0 0.2 7.8e-29 100.4 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RUS78342.1 - 1.5e-08 34.9 1.3 3.1e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Ank_2 PF12796.7 RUS78343.1 - 8.2e-35 119.3 0.2 1.7e-10 41.3 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78343.1 - 6.5e-26 90.4 1.8 5.2e-11 42.9 0.2 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DHHC PF01529.20 RUS78343.1 - 3.2e-24 85.6 34.7 9.2e-23 80.8 27.7 3.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.6 RUS78343.1 - 3.3e-23 79.2 1.0 9.3e-05 22.5 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RUS78343.1 - 2.3e-21 75.5 3.2 1.7e-07 31.4 0.0 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS78343.1 - 2.4e-17 62.5 13.2 0.00013 22.3 0.1 7.3 7 0 0 7 7 7 4 Ankyrin repeat DUF2284 PF10050.9 RUS78343.1 - 8 6.2 9.5 8.2 6.1 0.1 2.4 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) AMP-binding PF00501.28 RUS78344.1 - 9.3e-73 245.2 0.0 2.6e-72 243.8 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 RUS78344.1 - 1.7e-55 188.0 0.0 3e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 RUS78344.1 - 2e-55 187.3 8.1 5e-55 186.0 5.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS78344.1 - 4.8e-40 137.6 6.3 9.4e-40 136.6 5.5 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RUS78344.1 - 5.4e-18 65.3 2.2 9.6e-14 51.4 0.2 3.8 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 RUS78344.1 - 1e-15 57.8 0.5 2.3e-15 56.7 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 RUS78344.1 - 2.2e-15 57.0 6.6 9.6e-13 48.4 2.9 2.5 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 RUS78344.1 - 3.7e-12 45.8 3.6 1.8e-10 40.3 0.4 3.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 RUS78344.1 - 1.4e-07 32.4 0.4 1.3e-06 29.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 RUS78344.1 - 2.9e-07 30.6 5.5 0.0026 17.7 1.4 4.0 3 1 1 4 4 4 2 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RUS78344.1 - 3.4e-06 26.7 0.1 0.0097 15.3 0.0 3.2 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RUS78344.1 - 5.9e-06 25.6 8.9 0.00056 19.1 1.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RUS78344.1 - 2.9e-05 23.3 2.7 0.0034 16.5 0.0 3.3 3 0 0 3 3 3 1 RmlD substrate binding domain DFP PF04127.15 RUS78344.1 - 0.027 14.3 1.6 0.092 12.6 1.6 1.8 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 RUS78344.1 - 0.077 12.3 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 RUS78344.1 - 0.12 12.2 0.9 0.28 11.0 0.9 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_59M PF17387.2 RUS78345.1 - 0.00093 19.3 1.9 1.2 9.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 59 central domain CdiI_4 PF18624.1 RUS78345.1 - 0.0012 19.2 1.7 1.9 9.0 0.1 2.6 2 0 0 2 2 2 2 CDI immunity protein RolB_RolC PF02027.17 RUS78345.1 - 0.0036 17.0 0.2 3 7.5 0.0 2.2 2 0 0 2 2 2 2 RolB/RolC glucosidase family DUF4449 PF14613.6 RUS78345.1 - 0.029 14.5 0.3 7.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) FragX_IP PF05994.11 RUS78346.1 - 0 1191.9 1.8 0 1191.5 1.8 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 RUS78346.1 - 6.7e-09 35.4 7.6 3.5e-08 33.1 7.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) BP28CT PF08146.12 RUS78346.1 - 0.028 14.3 0.1 0.095 12.5 0.1 1.9 1 0 0 1 1 1 0 BP28CT (NUC211) domain zf-C2H2 PF00096.26 RUS78347.1 - 1.1e-22 79.1 72.3 0.00015 22.0 0.3 9.9 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78347.1 - 1.4e-22 79.1 68.3 2.1e-06 27.9 1.2 10.2 10 0 0 10 10 9 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78347.1 - 1.4e-21 75.3 76.8 0.0016 19.1 0.4 10.5 10 0 0 10 10 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS78347.1 - 8.1e-10 38.7 35.2 0.13 12.5 0.7 9.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS78347.1 - 6.8e-07 29.5 45.6 0.026 14.9 1.4 9.3 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS78347.1 - 1.1e-05 25.1 35.1 0.0034 17.1 2.6 6.2 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS78347.1 - 0.00032 20.6 1.2 0.00032 20.6 1.2 9.8 9 1 0 9 9 9 4 C2H2-type zinc finger zf-RING_7 PF02591.15 RUS78347.1 - 0.022 14.9 3.7 10 6.4 0.1 4.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF2256 PF10013.9 RUS78347.1 - 0.12 12.5 23.3 4.1 7.6 0.0 7.5 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 RUS78347.1 - 1.4 9.7 35.0 2.7 8.8 4.0 5.2 1 1 4 5 5 5 0 zinc-ribbon family ADK_lid PF05191.14 RUS78347.1 - 5.9 7.0 22.7 4.5 7.3 0.3 5.4 2 2 3 5 5 5 0 Adenylate kinase, active site lid Methyltransf_23 PF13489.6 RUS78348.1 - 7e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ABC_cobalt PF09819.9 RUS78348.1 - 0.024 14.7 1.0 0.076 13.2 0.1 1.9 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component MetW PF07021.12 RUS78348.1 - 0.045 13.3 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 RUS78348.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_25 PF13649.6 RUS78348.1 - 0.097 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 RUS78348.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Sugar_tr PF00083.24 RUS78349.1 - 6e-31 107.8 23.2 7.3e-31 107.5 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS78349.1 - 2.2e-27 95.9 31.7 2.4e-14 53.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS78349.1 - 0.0002 20.3 18.7 0.0006 18.8 18.2 2.0 1 1 1 2 2 2 1 MFS_1 like family MFS_1 PF07690.16 RUS78350.1 - 0.16 10.8 33.6 0.0042 16.0 25.9 2.2 1 1 1 2 2 2 0 Major Facilitator Superfamily NDUF_B12 PF08122.12 RUS78350.1 - 0.68 10.0 2.5 1.2 9.3 0.1 2.6 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Aa_trans PF01490.18 RUS78351.1 - 2.4e-71 240.6 20.7 3.9e-58 197.1 16.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MotA_ExbB PF01618.16 RUS78351.1 - 0.04 13.7 0.1 0.04 13.7 0.1 1.9 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Galactosyl_T PF01762.21 RUS78352.1 - 1.5e-13 51.0 0.1 2.1e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 RUS78353.1 - 5.8e-34 117.6 0.0 8.9e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Glyco_hydro_31 PF01055.26 RUS78353.1 - 0.026 13.7 0.1 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 VWD PF00094.25 RUS78356.1 - 8.1e-13 48.9 0.3 1.7e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_2 PF07974.13 RUS78356.1 - 0.0044 17.3 11.8 0.0044 17.3 11.8 3.9 3 0 0 3 3 3 1 EGF-like domain RGM_C PF06534.13 RUS78356.1 - 0.043 13.3 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus FMO-like PF00743.19 RUS78357.1 - 2e-95 320.2 0.0 2.6e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS78357.1 - 2e-25 89.7 0.0 5.2e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS78357.1 - 4.1e-15 55.8 0.0 2.9e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS78357.1 - 3.9e-12 46.0 0.2 3.6e-10 39.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RUS78357.1 - 1.8e-09 37.7 0.1 3.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 RUS78357.1 - 6.7e-07 28.9 0.0 7.8e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 RUS78357.1 - 9.8e-07 28.7 0.2 5.6e-05 22.9 0.3 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS78357.1 - 2e-06 27.2 0.1 5e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS78357.1 - 1.1e-05 24.8 0.1 2.1e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 RUS78357.1 - 1.4e-05 24.7 0.2 2.4e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS78357.1 - 0.00016 20.5 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein IlvN PF07991.12 RUS78357.1 - 0.00037 20.1 0.1 0.0085 15.7 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 RUS78357.1 - 0.00046 19.5 0.3 0.00088 18.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 RUS78357.1 - 0.0012 19.4 1.0 0.19 12.3 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS78357.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 RUS78357.1 - 0.0015 18.5 0.0 0.18 11.8 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RUS78357.1 - 0.035 13.2 0.6 0.05 12.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 RUS78357.1 - 0.044 13.8 0.1 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 RUS78357.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TAFH PF07531.14 RUS78358.1 - 4.4e-08 33.1 1.8 52 4.0 0.0 7.7 2 1 5 8 8 8 0 NHR1 homology to TAF Acylphosphatase PF00708.18 RUS78358.1 - 3.8e-07 30.4 1.1 2.6 8.5 0.0 5.0 2 1 3 5 5 5 1 Acylphosphatase Fungal_trans PF04082.18 RUS78358.1 - 2.7e-05 23.4 5.5 1.1 8.2 1.6 4.9 1 1 2 3 3 3 2 Fungal specific transcription factor domain HKR_ArcB_TM PF18415.1 RUS78358.1 - 2.8e-05 24.8 1.4 36 5.2 0.0 5.0 2 1 5 7 7 7 0 Histidine kinase receptor ArcB trans-membrane domain DUF1943 PF09172.11 RUS78358.1 - 0.00014 21.2 0.0 0.23 10.7 0.0 4.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1943) Beta_helix PF13229.6 RUS78358.1 - 0.014 15.2 4.9 1.8 8.4 1.4 2.4 1 1 1 2 2 2 0 Right handed beta helix region Pom PF17251.2 RUS78358.1 - 0.015 14.6 2.9 1.8 7.8 0.1 3.0 1 1 2 3 3 3 0 Protochlamydia outer membrane protein EZH2_N PF18601.1 RUS78358.1 - 1.8 9.0 24.1 3.6 8.0 0.4 4.6 2 1 1 5 5 5 0 EZH2 N-terminal domain ThiS-like PF14453.6 RUS78358.1 - 2.6 8.2 15.0 3.5e+02 1.3 0.0 7.6 10 0 0 10 10 10 0 ThiS-like ubiquitin S4 PF01479.25 RUS78358.1 - 4 7.2 29.0 1.1e+02 2.6 0.0 9.1 10 0 0 10 10 10 0 S4 domain rpo30_N PF12410.8 RUS78358.1 - 8.8 6.2 24.2 23 4.9 0.4 5.2 1 1 4 6 6 6 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit C1_1 PF00130.22 RUS78359.1 - 8.9e-07 28.7 10.5 0.0017 18.2 0.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RUS78359.1 - 0.013 15.0 12.0 0.3 10.7 1.2 2.3 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.6 RUS78359.1 - 0.089 12.7 11.2 0.39 10.6 3.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RUS78359.1 - 0.11 12.2 10.1 0.44 10.2 2.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 RUS78359.1 - 0.59 10.5 13.9 1.1 9.7 1.8 2.3 2 0 0 2 2 2 0 RING-like domain PHD PF00628.29 RUS78359.1 - 2.4 8.1 12.2 3 7.8 1.3 2.2 2 0 0 2 2 2 0 PHD-finger DUF1815 PF08844.10 RUS78359.1 - 2.8 8.0 5.1 9 6.3 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) HTH_ABP1_N PF18107.1 RUS78360.1 - 3.3e-05 23.5 4.2 1.2 8.9 0.1 3.3 3 0 0 3 3 3 3 Fission yeast centromere protein N-terminal domain DUF3864 PF12980.7 RUS78360.1 - 0.0032 17.8 1.3 9.8 6.6 0.0 3.3 3 0 0 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3864) PepX_C PF08530.10 RUS78360.1 - 0.088 12.7 1.0 0.15 12.0 0.3 1.8 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain NmrA PF05368.13 RUS78361.1 - 1.3e-16 60.9 0.0 4.4e-14 52.6 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 RUS78361.1 - 1.3e-11 44.7 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RUS78361.1 - 9.2e-05 21.6 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS78361.1 - 0.00022 20.8 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4281 PF14108.6 RUS78361.1 - 0.04 14.3 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Semialdhyde_dh PF01118.24 RUS78361.1 - 0.049 14.1 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Neur_chan_LBD PF02931.23 RUS78362.1 - 5.5e-22 78.3 2.2 5.5e-22 78.3 2.2 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Ead_Ea22 PF13935.6 RUS78364.1 - 0.099 13.3 0.3 0.16 12.6 0.3 1.6 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF1619 PF07773.11 RUS78364.1 - 0.17 11.8 1.1 0.26 11.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) EF1_GNE PF00736.19 RUS78365.1 - 1.8e-32 111.3 2.7 4.9e-32 110.0 2.7 1.8 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RUS78365.1 - 1.7e-09 37.9 2.9 1.7e-09 37.9 2.9 3.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region TPR_7 PF13176.6 RUS78365.1 - 0.0098 15.9 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat ETRAMP PF09716.10 RUS78365.1 - 2.4 8.3 4.8 58 3.9 4.8 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Fes1 PF08609.10 RUS78365.1 - 3.7 8.5 8.5 4.3 8.3 0.4 3.4 2 1 2 4 4 4 0 Nucleotide exchange factor Fes1 HMG_box PF00505.19 RUS78366.1 - 3.5e-15 56.2 17.6 4.9e-07 30.1 0.6 3.8 3 0 0 3 3 3 3 HMG (high mobility group) box YlbE PF14003.6 RUS78366.1 - 0.0087 16.5 3.7 2.9 8.4 0.0 2.6 2 0 0 2 2 2 2 YlbE-like protein Myb_DNA-binding PF00249.31 RUS78366.1 - 0.015 15.4 0.0 0.061 13.5 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cyclin_N PF00134.23 RUS78367.1 - 1e-07 31.7 0.7 2.3e-07 30.6 0.7 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain HMG_box_2 PF09011.10 RUS78368.1 - 0.3 11.7 4.5 1.2 9.8 4.5 2.1 1 0 0 1 1 1 0 HMG-box domain Cse1 PF08506.10 RUS78370.1 - 3.6e-159 529.5 7.3 9.5e-159 528.1 7.3 1.8 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 RUS78370.1 - 1.1e-154 515.3 3.5 1.4e-154 514.9 0.2 2.6 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 RUS78370.1 - 3.7e-13 49.2 0.0 2e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RUS78370.1 - 0.0025 17.9 0.4 0.0025 17.9 0.4 3.5 4 0 0 4 4 4 1 Exportin 1-like protein UME PF08064.13 RUS78370.1 - 0.054 13.4 0.4 18 5.3 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain Strumpellin PF10266.9 RUS78371.1 - 0 1642.4 22.1 0 1642.3 22.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Hist_deacetyl PF00850.19 RUS78372.1 - 6.6e-87 291.8 0.4 1.7e-86 290.5 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain SHIPPO-rpt PF07004.12 RUS78373.1 - 4.3e-07 30.5 18.0 0.16 12.9 0.0 7.5 8 0 0 8 8 8 4 Sperm-tail PG-rich repeat SMC_Nse1 PF07574.13 RUS78374.1 - 7.7e-27 94.4 0.0 2.2e-24 86.4 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 RUS78374.1 - 3.5e-05 24.0 11.4 6.7e-05 23.1 11.4 1.5 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.22 RUS78374.1 - 0.00015 21.5 5.5 0.00028 20.7 5.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Tubulin PF00091.25 RUS78374.1 - 0.013 15.7 0.2 0.032 14.4 0.1 1.6 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain zf-RING_2 PF13639.6 RUS78374.1 - 0.043 14.2 10.7 0.088 13.2 10.7 1.6 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 RUS78374.1 - 2.6 8.0 9.8 5.1 7.1 9.8 1.5 1 0 0 1 1 1 0 PHD-finger DEAD PF00270.29 RUS78375.1 - 5e-40 137.1 0.0 1.1e-39 136.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS78375.1 - 6e-27 94.2 0.0 1.7e-25 89.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS78375.1 - 0.0015 18.6 6.7 0.0019 18.2 0.0 3.7 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RUS78375.1 - 0.0046 17.2 3.3 0.04 14.2 0.0 3.7 4 1 0 4 4 4 1 AAA domain EF-hand_2 PF09068.11 RUS78377.1 - 1.5e-30 105.8 0.1 2.4e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 RUS78377.1 - 2e-19 69.8 0.0 4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 RUS78377.1 - 2.9e-10 39.8 9.9 6.4e-10 38.7 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RUS78377.1 - 0.00015 22.0 9.8 0.00033 20.9 9.8 1.6 1 0 0 1 1 1 1 C1 domain Baculo_IE-1 PF05290.11 RUS78377.1 - 0.0083 16.1 1.2 0.015 15.3 1.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RanBP PF00641.18 RUS78378.1 - 2.2e-11 42.8 2.0 4e-11 42.0 2.0 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others ZFYVE21_C PF16696.5 RUS78379.1 - 1.1e-26 93.1 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 RUS78379.1 - 5e-15 55.4 17.1 8.4e-15 54.7 17.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger LolA_like PF17131.4 RUS78379.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein DUF2428 PF10350.9 RUS78380.1 - 2.9e-79 266.2 0.0 9.2e-79 264.5 0.0 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 RUS78380.1 - 0.016 15.4 9.0 25 5.5 0.1 6.5 6 0 0 6 6 6 0 HEAT repeat Beach PF02138.18 RUS78381.1 - 4e-41 141.2 0.0 1.8e-40 139.1 0.0 2.1 2 0 0 2 2 2 1 Beige/BEACH domain Pkinase PF00069.25 RUS78381.1 - 0.0073 15.7 0.2 0.017 14.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Helicase_C PF00271.31 RUS78382.1 - 7.6e-15 55.2 0.0 2.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FAM176 PF14851.6 RUS78382.1 - 0.27 10.9 1.0 0.38 10.4 1.0 1.2 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 RUS78382.1 - 2.9 5.9 6.2 0.13 10.3 0.3 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen La PF05383.17 RUS78383.1 - 1.5e-15 57.0 0.0 2.4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 La domain AF-4 PF05110.13 RUS78384.1 - 0.00066 17.9 24.5 0.00075 17.7 24.5 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Glt_symporter PF03616.14 RUS78384.1 - 0.0083 14.9 0.3 0.011 14.5 0.3 1.2 1 0 0 1 1 1 1 Sodium/glutamate symporter GAGA_bind PF06217.12 RUS78384.1 - 0.021 15.1 17.6 0.025 14.8 17.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Red1 PF07964.11 RUS78384.1 - 0.056 11.7 29.9 0.055 11.7 29.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RR_TM4-6 PF06459.12 RUS78384.1 - 0.067 13.0 17.9 0.079 12.8 17.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 RUS78384.1 - 0.085 12.6 12.9 0.097 12.4 12.9 1.2 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 RUS78384.1 - 0.088 12.6 13.5 0.11 12.2 13.5 1.3 1 0 0 1 1 1 0 Connexin RPOL_N PF14700.6 RUS78384.1 - 0.095 12.1 16.8 0.12 11.8 16.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Zip PF02535.22 RUS78384.1 - 0.1 11.8 10.4 0.1 11.8 10.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter eIF3_subunit PF08597.10 RUS78384.1 - 0.11 12.5 28.5 0.15 12.0 28.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit LicD PF04991.13 RUS78384.1 - 0.13 12.4 11.9 0.16 12.1 11.9 1.2 1 0 0 1 1 1 0 LicD family Pox_Ag35 PF03286.14 RUS78384.1 - 0.31 10.8 26.9 0.32 10.7 26.3 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein SpoIIP PF07454.11 RUS78384.1 - 0.31 10.4 17.0 0.45 9.9 17.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Folate_carrier PF01770.18 RUS78384.1 - 0.4 9.4 7.1 0.52 9.0 7.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 RUS78384.1 - 0.63 8.8 15.9 0.68 8.7 15.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4770 PF15994.5 RUS78384.1 - 0.8 9.9 23.0 1.3 9.3 23.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SLC12 PF03522.15 RUS78384.1 - 0.81 8.6 17.3 0.93 8.4 17.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 RUS78384.1 - 0.98 7.4 18.4 1.3 7.1 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 RUS78384.1 - 1 7.5 17.2 1.2 7.3 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.15 RUS78384.1 - 1.1 8.1 4.0 1.1 8.1 4.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF5427 PF10310.9 RUS78384.1 - 1.2 8.0 20.5 1.3 7.9 20.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SAPS PF04499.15 RUS78384.1 - 1.5 7.5 14.4 1.9 7.2 14.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 RUS78384.1 - 2.2 6.1 15.2 2.7 5.8 15.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NARP1 PF12569.8 RUS78384.1 - 2.6 6.9 26.8 3.3 6.5 26.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCM_bind PF09739.9 RUS78384.1 - 5.4 5.3 17.6 6.7 5.0 17.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GREB1 PF15782.5 RUS78384.1 - 6.8 3.7 15.3 7.2 3.6 15.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CLN3 PF02487.17 RUS78384.1 - 6.8 5.6 10.1 8.2 5.4 10.1 1.1 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 RUS78384.1 - 8.6 5.2 6.7 11 4.9 6.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 RUS78384.1 - 9.5 5.1 11.4 11 4.9 11.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 RUS78384.1 - 9.7 4.5 5.4 9.9 4.4 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2457 PF10446.9 RUS78385.1 - 0.00018 20.8 17.8 0.00041 19.6 17.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SpoIISA_toxin PF14171.6 RUS78385.1 - 0.00061 19.6 2.3 0.0014 18.3 2.3 1.6 1 0 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system CDC45 PF02724.14 RUS78385.1 - 0.0031 15.9 20.3 0.0056 15.0 20.3 1.4 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 RUS78385.1 - 0.0087 16.5 8.1 0.024 15.1 8.1 1.7 1 0 0 1 1 1 1 RNA polymerase III RPC4 Anoctamin PF04547.12 RUS78385.1 - 0.019 13.8 0.9 0.033 13.1 0.9 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel MA3 PF02847.17 RUS78385.1 - 0.028 14.4 0.2 0.076 13.0 0.2 1.8 1 0 0 1 1 1 0 MA3 domain Pex14_N PF04695.13 RUS78385.1 - 0.15 12.7 8.4 0.37 11.4 8.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 RUS78385.1 - 0.17 12.0 15.8 1.5 8.9 2.8 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RR_TM4-6 PF06459.12 RUS78385.1 - 0.22 11.3 27.2 0.086 12.7 23.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 RUS78385.1 - 0.23 10.2 16.3 0.41 9.3 16.3 1.4 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 RUS78385.1 - 0.27 11.4 15.5 1.1 9.4 15.5 2.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 RUS78385.1 - 0.62 9.4 38.9 0.021 14.3 32.2 1.9 2 0 0 2 2 2 0 SDA1 CCSAP PF15748.5 RUS78385.1 - 0.94 9.6 20.5 2.5 8.2 20.5 1.7 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF3306 PF11748.8 RUS78385.1 - 1.4 9.8 15.0 6 7.8 15.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CCDC53 PF10152.9 RUS78385.1 - 2.4 8.5 15.3 3.5 8.0 12.1 2.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Roughex PF06020.11 RUS78385.1 - 2.5 7.1 18.5 5.6 6.0 18.5 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Connexin PF00029.19 RUS78385.1 - 2.6 7.7 13.6 5.2 6.7 13.6 1.5 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 RUS78385.1 - 3.1 6.7 13.2 0.82 8.6 9.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Androgen_recep PF02166.16 RUS78385.1 - 4 6.2 6.9 7.1 5.3 6.9 1.3 1 0 0 1 1 1 0 Androgen receptor Zip PF02535.22 RUS78385.1 - 5.2 6.2 12.9 0.36 10.0 7.7 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Paf1 PF03985.13 RUS78385.1 - 7.2 5.5 42.4 12 4.7 42.4 1.3 1 0 0 1 1 1 0 Paf1 DUF3391 PF11871.8 RUS78385.1 - 7.7 7.1 16.5 50 4.4 16.5 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) HCO3_cotransp PF00955.21 RUS78387.1 - 2.3e-229 762.5 8.0 2.9e-229 762.1 8.0 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RUS78387.1 - 2.4e-96 322.7 0.0 3.8e-96 322.0 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain MFS_MOT1 PF16983.5 RUS78387.1 - 3.3 8.1 7.2 2.1 8.8 3.1 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily SDA1 PF05285.12 RUS78388.1 - 0.0044 16.5 42.8 0.0051 16.3 42.8 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 RUS78388.1 - 0.037 13.4 40.4 0.044 13.1 40.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS78388.1 - 0.044 12.0 44.4 0.059 11.6 44.4 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS78388.1 - 1.9 7.2 14.5 2.2 7.0 14.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Drf_GBD PF06371.13 RUS78389.1 - 6e-09 35.7 0.0 7.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Kinesin PF00225.23 RUS78390.1 - 5.3e-102 341.2 0.8 1.3e-101 339.9 0.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS78390.1 - 1.7e-28 99.5 0.0 6.6e-28 97.5 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding PTPlike_phytase PF14566.6 RUS78390.1 - 0.51 10.4 4.2 9.5 6.3 1.6 3.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Ank_2 PF12796.7 RUS78391.1 - 3.8e-60 200.4 16.5 1.4e-11 44.8 0.9 9.5 5 4 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS78391.1 - 2.3e-46 155.3 16.5 9.1e-09 35.4 0.2 11.4 9 2 3 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS78391.1 - 3e-43 145.7 18.1 5.5e-08 33.2 0.6 15.7 6 4 10 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78391.1 - 9.8e-39 127.0 26.0 7.5e-05 22.8 0.0 16.2 17 0 0 17 17 17 7 Ankyrin repeat Ank PF00023.30 RUS78391.1 - 1.6e-37 126.3 26.9 3.9e-05 23.9 0.0 13.5 13 0 0 13 13 13 9 Ankyrin repeat Phage_T7_Capsid PF05396.11 RUS78391.1 - 0.099 13.0 0.9 12 6.3 0.2 2.7 2 0 0 2 2 2 0 Phage T7 capsid assembly protein DUF1843 PF08898.10 RUS78391.1 - 1.8 9.1 4.5 10 6.7 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Phospho_p8 PF10195.9 RUS78393.1 - 7 7.2 11.4 64 4.2 0.0 2.7 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 UQ_con PF00179.26 RUS78394.1 - 1.4e-34 118.7 0.1 1.7e-34 118.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS78394.1 - 0.0085 15.8 0.0 0.051 13.3 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B Prok-E2_A PF14457.6 RUS78394.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A Ras PF00071.22 RUS78395.1 - 5.6e-62 208.1 1.5 8.7e-62 207.5 1.5 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78395.1 - 3.2e-33 114.5 0.7 6.4e-33 113.5 0.7 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78395.1 - 2.8e-13 49.7 0.3 4.1e-13 49.1 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS78395.1 - 0.0003 20.3 0.3 0.001 18.5 0.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS78395.1 - 0.00043 20.4 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS78395.1 - 0.00055 19.4 0.1 0.00091 18.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS78395.1 - 0.00092 18.8 0.1 0.0033 17.0 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RUS78395.1 - 0.0079 15.7 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS78395.1 - 0.014 15.4 0.2 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 RUS78395.1 - 0.015 14.5 1.8 5 6.2 0.0 3.0 2 1 1 3 3 3 0 G-protein alpha subunit DUF3169 PF11368.8 RUS78397.1 - 0.021 14.3 0.8 0.036 13.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) AP_endonuc_2 PF01261.24 RUS78398.1 - 4.3e-26 91.7 0.0 4.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Atg14 PF10186.9 RUS78399.1 - 0.99 8.4 60.0 0.21 10.6 17.4 4.1 1 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 GLE1 PF07817.13 RUS78399.1 - 1.5 7.9 7.9 7.9 5.6 1.4 2.4 2 0 0 2 2 2 0 GLE1-like protein Baculo_PEP_C PF04513.12 RUS78399.1 - 4.1 7.4 24.0 0.12 12.4 0.7 4.8 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Imm7 PF15585.6 RUS78399.1 - 4.9 7.4 7.8 1.5 9.1 1.2 3.3 3 0 0 3 3 3 0 Immunity protein 7 zf-primase PF09329.11 RUS78400.1 - 0.051 13.4 11.7 3.1 7.7 1.8 3.6 1 1 1 3 3 3 0 Primase zinc finger BLOC1_2 PF10046.9 RUS78401.1 - 1.3e-11 44.7 8.7 0.0012 19.1 1.0 3.1 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 RUS78401.1 - 1.1e-10 41.5 7.6 0.00061 19.9 1.7 3.2 1 1 2 3 3 3 3 Haemolysin XhlA DUF4988 PF16378.5 RUS78401.1 - 1.4e-08 34.6 5.1 0.06 13.0 0.4 3.6 1 1 3 4 4 4 4 Domain of unknown function Tropomyosin_1 PF12718.7 RUS78401.1 - 4.2e-08 33.5 11.1 1.5e-05 25.1 11.6 2.3 1 1 0 1 1 1 1 Tropomyosin like FlaC_arch PF05377.11 RUS78401.1 - 1.7e-07 31.5 5.0 0.0052 17.2 1.3 2.9 1 1 1 2 2 2 2 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 RUS78401.1 - 4.2e-07 30.0 8.6 0.00065 19.7 1.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) BRI3BP PF14965.6 RUS78401.1 - 7.9e-07 28.8 17.9 0.046 13.2 0.4 4.1 1 1 2 3 3 3 2 Negative regulator of p53/TP53 DUF3251 PF11622.8 RUS78401.1 - 9e-07 28.7 16.0 0.036 13.7 0.9 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3251) TRAF_BIRC3_bd PF16673.5 RUS78401.1 - 1.4e-06 28.0 20.2 0.0045 16.8 7.8 4.7 1 1 2 3 3 3 2 TNF receptor-associated factor BIRC3 binding domain Sugarporin_N PF11471.8 RUS78401.1 - 1.7e-06 27.9 29.1 0.25 11.3 0.2 5.6 1 1 5 6 6 6 5 Maltoporin periplasmic N-terminal extension Tropomyosin PF00261.20 RUS78401.1 - 2e-06 27.4 18.1 1.7e-05 24.3 17.9 1.8 1 1 0 1 1 1 1 Tropomyosin ABC_tran_CTD PF16326.5 RUS78401.1 - 2.1e-06 27.9 5.1 0.085 13.1 4.9 3.8 1 1 1 2 2 2 1 ABC transporter C-terminal domain Fib_alpha PF08702.10 RUS78401.1 - 2.2e-06 27.9 13.8 0.0047 17.1 6.3 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 RUS78401.1 - 4.9e-06 26.5 27.0 0.068 13.3 2.8 3.9 1 1 3 4 4 4 4 Basic region leucine zipper DUF16 PF01519.16 RUS78401.1 - 5e-06 26.9 12.1 0.015 15.8 5.8 2.5 1 1 1 2 2 2 2 Protein of unknown function DUF16 Lzipper-MIP1 PF14389.6 RUS78401.1 - 6.2e-06 26.4 14.8 0.99 9.7 5.6 4.3 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CLZ PF16526.5 RUS78401.1 - 6.7e-06 26.4 21.0 0.017 15.5 10.2 3.1 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 RUS78401.1 - 7.3e-06 26.0 13.3 0.047 13.8 0.6 3.4 1 1 2 3 3 3 2 bZIP transcription factor PspB PF06667.12 RUS78401.1 - 2e-05 24.6 21.6 0.31 11.1 5.9 5.0 1 1 2 3 3 3 1 Phage shock protein B CENP-F_leu_zip PF10473.9 RUS78401.1 - 2.1e-05 24.6 16.6 6.9e-05 22.9 16.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1465 PF07323.12 RUS78401.1 - 2.3e-05 24.3 13.0 0.0086 15.9 8.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1465) Laminin_II PF06009.12 RUS78401.1 - 4.6e-05 23.5 6.8 0.0038 17.3 1.1 2.2 1 1 1 2 2 2 2 Laminin Domain II Paralemmin PF03285.15 RUS78401.1 - 8.5e-05 22.3 17.1 0.12 11.9 1.9 3.2 1 1 2 3 3 3 3 Paralemmin Csm1_N PF18504.1 RUS78401.1 - 0.00013 22.2 21.4 0.27 11.6 1.2 3.4 1 1 2 3 3 3 1 Csm1 N-terminal domain Dynamitin PF04912.14 RUS78401.1 - 0.00014 21.3 13.0 0.00098 18.6 5.2 2.2 1 1 1 2 2 2 2 Dynamitin Uso1_p115_C PF04871.13 RUS78401.1 - 0.00014 22.2 6.8 0.011 16.1 3.9 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.11 RUS78401.1 - 0.00016 20.7 15.8 0.00024 20.1 15.8 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 RUS78401.1 - 0.00017 22.1 21.5 0.0038 17.8 5.1 2.3 1 1 1 2 2 2 1 SlyX TMF_DNA_bd PF12329.8 RUS78401.1 - 0.00028 20.8 8.4 0.03 14.3 2.8 2.9 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF2802 PF10975.8 RUS78401.1 - 0.00029 20.9 17.7 0.32 11.2 0.9 4.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2802) Atg14 PF10186.9 RUS78401.1 - 0.0004 19.6 11.8 0.00051 19.2 11.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 RUS78401.1 - 0.00042 20.2 15.9 0.19 11.7 2.8 3.2 1 1 2 3 3 3 2 Prefoldin subunit Exonuc_VII_L PF02601.15 RUS78401.1 - 0.0005 19.7 10.4 0.0006 19.5 10.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Dynactin_p22 PF07426.11 RUS78401.1 - 0.00051 20.0 14.8 0.81 9.5 0.2 4.8 1 1 3 4 4 4 1 Dynactin subunit p22 Ax_dynein_light PF10211.9 RUS78401.1 - 0.00057 19.9 16.1 0.35 10.8 0.6 3.0 1 1 2 3 3 3 2 Axonemal dynein light chain NPV_P10 PF05531.12 RUS78401.1 - 0.00064 20.1 2.5 0.53 10.8 2.5 2.9 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Exonuc_VII_S PF02609.16 RUS78401.1 - 0.00065 19.7 3.7 3.2 7.9 0.2 4.0 1 1 4 5 5 5 0 Exonuclease VII small subunit Phage_GP20 PF06810.11 RUS78401.1 - 0.00087 19.1 1.1 0.12 12.2 1.1 2.2 1 1 0 1 1 1 1 Phage minor structural protein GP20 ATG16 PF08614.11 RUS78401.1 - 0.0011 19.3 22.2 0.079 13.2 8.6 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4635 PF15466.6 RUS78401.1 - 0.0012 18.3 17.6 1.7 8.2 2.6 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4635) DUF2730 PF10805.8 RUS78401.1 - 0.0014 18.7 10.9 0.12 12.5 5.9 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 RUS78401.1 - 0.0015 18.6 1.1 0.0032 17.5 1.1 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_tail_NK PF16532.5 RUS78401.1 - 0.0016 18.1 4.3 3.3 7.3 1.4 3.1 1 1 1 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales Surfac_D-trimer PF09006.11 RUS78401.1 - 0.0016 18.3 19.5 5.9 6.9 3.0 5.6 1 1 3 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation GAS PF13851.6 RUS78401.1 - 0.0019 17.6 16.6 0.034 13.5 9.3 2.2 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.8 RUS78401.1 - 0.0021 18.1 19.3 0.022 14.8 12.2 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 RUS78401.1 - 0.0021 16.8 4.7 0.0037 16.0 4.7 1.4 1 1 0 1 1 1 1 AAA domain DUF4686 PF15742.5 RUS78401.1 - 0.0026 17.0 25.3 0.019 14.1 17.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4686) ZapB PF06005.12 RUS78401.1 - 0.0031 17.9 19.6 0.24 11.9 5.6 2.9 1 1 2 3 3 2 2 Cell division protein ZapB Filament PF00038.21 RUS78401.1 - 0.0039 16.8 12.0 1.3 8.5 1.2 2.9 1 1 2 3 3 3 0 Intermediate filament protein Noelin-1 PF12308.8 RUS78401.1 - 0.0039 17.1 16.8 0.049 13.6 8.8 2.2 1 1 2 3 3 3 2 Neurogenesis glycoprotein Myosin_tail_1 PF01576.19 RUS78401.1 - 0.0039 15.1 14.7 0.0049 14.7 14.7 1.0 1 0 0 1 1 1 1 Myosin tail DUF724 PF05266.14 RUS78401.1 - 0.0048 16.7 7.9 0.025 14.4 7.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF724) MAD PF05557.13 RUS78401.1 - 0.0051 15.3 15.0 0.0077 14.7 15.0 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein Vac_Fusion PF02346.16 RUS78401.1 - 0.0054 16.3 16.0 0.52 10.0 6.0 3.2 1 1 2 3 3 3 2 Chordopoxvirus multifunctional envelope protein A27 KLRAQ PF10205.9 RUS78401.1 - 0.0067 16.6 16.7 1.1 9.6 9.1 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein CEP209_CC5 PF16574.5 RUS78401.1 - 0.0068 16.6 12.2 0.0099 16.0 12.2 1.3 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 Prominin PF05478.11 RUS78401.1 - 0.0084 14.1 5.7 0.07 11.1 5.7 1.9 1 1 0 1 1 1 1 Prominin TRPM_tetra PF16519.5 RUS78401.1 - 0.0085 16.2 19.9 0.29 11.3 2.6 2.6 1 1 1 2 2 2 1 Tetramerisation domain of TRPM EzrA PF06160.12 RUS78401.1 - 0.0087 14.3 7.9 0.012 13.8 7.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SKA1 PF07160.12 RUS78401.1 - 0.009 15.9 9.5 1.6 8.5 9.5 2.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 HCMV_UL139 PF12507.8 RUS78401.1 - 0.0093 16.3 11.3 12 6.3 0.0 3.6 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein FPP PF05911.11 RUS78401.1 - 0.0093 14.2 11.7 0.011 13.9 11.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF3552 PF12072.8 RUS78401.1 - 0.011 15.2 21.1 19 4.6 21.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) PspA_IM30 PF04012.12 RUS78401.1 - 0.012 15.2 14.5 0.058 13.0 1.2 2.1 1 1 1 2 2 2 0 PspA/IM30 family FliD_C PF07195.12 RUS78401.1 - 0.012 15.0 7.4 2.2 7.6 0.3 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Snapin_Pallidin PF14712.6 RUS78401.1 - 0.012 16.0 14.2 0.16 12.4 10.9 3.1 1 1 1 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 RUS78401.1 - 0.012 14.5 11.3 0.018 14.0 11.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.6 RUS78401.1 - 0.012 15.2 19.4 0.022 14.4 19.4 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Troponin PF00992.20 RUS78401.1 - 0.013 15.8 19.3 0.11 12.8 19.3 2.0 1 1 0 1 1 1 0 Troponin DUF812 PF05667.11 RUS78401.1 - 0.013 14.4 12.9 0.016 14.1 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF465 PF04325.13 RUS78401.1 - 0.013 15.5 4.8 13 5.9 0.3 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF465) DUF4472 PF14739.6 RUS78401.1 - 0.014 16.1 12.9 0.16 12.7 3.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Jnk-SapK_ap_N PF09744.9 RUS78401.1 - 0.015 15.5 19.7 0.55 10.4 2.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 RUS78401.1 - 0.015 15.9 8.3 6.3 7.5 8.2 2.4 1 1 0 1 1 1 0 Initiation control protein YabA DASH_Dam1 PF08653.10 RUS78401.1 - 0.02 14.7 0.0 17 5.3 0.0 3.3 1 1 3 4 4 4 0 DASH complex subunit Dam1 PGBA_C PF15437.6 RUS78401.1 - 0.022 15.1 19.8 5.2 7.5 1.1 3.9 1 1 2 3 3 3 0 Plasminogen-binding protein pgbA C-terminal Fungal_trans_2 PF11951.8 RUS78401.1 - 0.024 13.5 5.0 2.1 7.1 5.0 2.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF948 PF06103.11 RUS78401.1 - 0.025 14.8 3.3 0.78 10.0 3.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Nsp1_C PF05064.13 RUS78401.1 - 0.028 14.2 8.3 0.41 10.5 2.6 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Laminin_I PF06008.14 RUS78401.1 - 0.029 14.1 9.1 0.17 11.5 9.2 1.8 1 1 0 1 1 1 0 Laminin Domain I HemX PF04375.14 RUS78401.1 - 0.032 13.5 14.0 0.21 10.9 14.0 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase STAT_alpha PF01017.20 RUS78401.1 - 0.032 14.1 12.5 0.28 11.1 5.3 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain ERM PF00769.19 RUS78401.1 - 0.035 13.9 15.7 0.047 13.5 15.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4795 PF16043.5 RUS78401.1 - 0.035 13.7 8.7 0.7 9.5 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DivIC PF04977.15 RUS78401.1 - 0.037 13.8 15.5 1.2 8.9 0.7 3.1 1 1 2 3 3 3 0 Septum formation initiator BRE1 PF08647.11 RUS78401.1 - 0.042 13.9 7.2 0.43 10.7 1.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TelA PF05816.11 RUS78401.1 - 0.043 12.9 8.7 0.093 11.8 8.7 1.7 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) GerPC PF10737.9 RUS78401.1 - 0.044 13.9 10.1 26 4.8 0.1 3.9 1 1 1 2 2 2 0 Spore germination protein GerPC Syntaxin-6_N PF09177.11 RUS78401.1 - 0.044 14.3 10.3 1.8 9.2 6.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc110_C PF18520.1 RUS78401.1 - 0.051 13.2 11.8 3.5 7.3 1.6 4.7 1 1 4 5 5 5 0 Spindle pole body component 110 C-terminal domain Prefoldin_3 PF13758.6 RUS78401.1 - 0.052 13.6 20.1 4.5 7.4 1.7 3.1 1 1 2 3 3 3 0 Prefoldin subunit GP41 PF00517.17 RUS78401.1 - 0.054 13.4 13.6 1.7 8.5 2.2 3.1 1 1 2 3 3 3 0 Retroviral envelope protein BRCC36_C PF18110.1 RUS78401.1 - 0.058 13.6 14.3 6.5 7.0 0.2 4.2 1 1 5 6 6 6 0 BRCC36 C-terminal helical domain DUF4618 PF15397.6 RUS78401.1 - 0.063 12.7 13.4 1.2 8.5 7.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Phage_GPO PF05929.11 RUS78401.1 - 0.074 12.7 8.5 0.24 11.0 5.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Lambda_tail_I PF06805.12 RUS78401.1 - 0.076 13.4 4.6 12 6.3 0.1 3.1 1 1 2 3 3 3 0 Bacteriophage lambda tail assembly protein I DUF5320 PF17253.2 RUS78401.1 - 0.079 14.0 9.5 2.4 9.3 1.3 3.3 1 1 0 2 2 2 0 Family of unknown function (DUF5320) HOOK PF05622.12 RUS78401.1 - 0.082 11.0 18.0 0.24 9.5 18.0 1.7 1 1 0 1 1 1 0 HOOK protein DUF1515 PF07439.11 RUS78401.1 - 0.085 12.9 12.0 2.4 8.2 10.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) PRELI PF04707.14 RUS78401.1 - 0.086 12.7 3.7 0.1 12.4 3.7 1.1 1 0 0 1 1 1 0 PRELI-like family Swi5 PF07061.11 RUS78401.1 - 0.092 12.8 4.9 16 5.6 3.8 3.0 1 1 1 2 2 2 0 Swi5 CdvA PF18822.1 RUS78401.1 - 0.093 12.6 10.5 9.7 6.0 1.2 3.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain HrpB7 PF09486.10 RUS78401.1 - 0.094 13.1 20.8 1 9.7 6.1 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) MbeD_MobD PF04899.12 RUS78401.1 - 0.096 12.8 22.5 2.9 8.1 2.8 3.3 1 1 2 3 3 3 0 MbeD/MobD like Spc24 PF08286.11 RUS78401.1 - 0.096 12.9 8.8 4.6 7.5 1.0 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF730 PF05325.11 RUS78401.1 - 0.1 12.6 0.8 8.4 6.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Occludin_ELL PF07303.13 RUS78401.1 - 0.13 13.0 8.6 1.4 9.7 8.6 2.2 1 1 0 1 1 1 0 Occludin homology domain V_ATPase_I PF01496.19 RUS78401.1 - 0.13 10.1 10.2 0.33 8.8 10.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 RUS78401.1 - 0.13 11.8 12.6 0.73 9.4 8.8 1.9 1 1 1 2 2 2 0 TMCO5 family Fmp27_WPPW PF10359.9 RUS78401.1 - 0.16 10.8 16.3 5.6 5.7 16.4 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMF_TATA_bd PF12325.8 RUS78401.1 - 0.17 12.1 18.0 0.82 9.9 11.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 RUS78401.1 - 0.17 10.4 9.8 0.2 10.1 9.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3287 PF11690.8 RUS78401.1 - 0.18 11.6 21.4 1.7 8.4 1.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF4446 PF14584.6 RUS78401.1 - 0.18 11.8 7.0 16 5.5 7.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF5082 PF16888.5 RUS78401.1 - 0.21 11.8 5.6 8.9 6.6 5.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ATP-synt_D PF01813.17 RUS78401.1 - 0.22 11.4 17.8 2.9 7.7 2.8 3.2 1 1 1 3 3 3 0 ATP synthase subunit D Cep57_CLD PF14073.6 RUS78401.1 - 0.24 11.4 20.0 0.81 9.7 20.0 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 TMPIT PF07851.13 RUS78401.1 - 0.24 10.6 5.8 0.35 10.1 5.8 1.4 1 1 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 RUS78401.1 - 0.26 9.8 3.9 0.58 8.7 4.0 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 RUS78401.1 - 0.27 10.8 12.8 0.84 9.2 7.1 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Striatin PF08232.12 RUS78401.1 - 0.29 11.7 14.1 0.95 10.0 0.3 3.0 1 1 1 2 2 2 0 Striatin family YscO PF07321.12 RUS78401.1 - 0.3 11.0 26.4 38 4.2 26.4 3.1 1 1 0 1 1 1 0 Type III secretion protein YscO Mod_r PF07200.13 RUS78401.1 - 0.31 11.2 10.3 1.4 9.0 10.3 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MPS2 PF17060.5 RUS78401.1 - 0.32 10.2 13.5 0.5 9.6 0.8 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 Nup54 PF13874.6 RUS78401.1 - 0.33 11.0 19.0 0.65 10.1 19.0 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 NuA4 PF09340.10 RUS78401.1 - 0.4 10.6 9.9 13 5.7 0.1 3.7 1 1 2 3 3 3 0 Histone acetyltransferase subunit NuA4 Sipho_Gp157 PF05565.11 RUS78401.1 - 0.43 10.6 4.3 1.4 8.9 1.6 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Uds1 PF15456.6 RUS78401.1 - 0.52 10.5 18.7 11 6.2 7.9 3.2 1 1 1 2 2 2 0 Up-regulated During Septation TolA_bind_tri PF16331.5 RUS78401.1 - 0.54 10.4 22.9 37 4.5 1.1 4.1 1 1 2 3 3 3 0 TolA binding protein trimerisation APG6_N PF17675.1 RUS78401.1 - 0.55 10.8 13.7 20 5.7 14.2 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Gp58 PF07902.11 RUS78401.1 - 0.55 8.5 10.0 1.2 7.3 10.0 1.5 1 1 0 1 1 1 0 gp58-like protein DUF4763 PF15960.5 RUS78401.1 - 0.57 9.4 18.9 1.6 8.0 18.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF3450 PF11932.8 RUS78401.1 - 0.58 9.4 17.1 0.8 9.0 12.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-Q PF13094.6 RUS78401.1 - 0.6 10.3 14.9 0.31 11.2 3.1 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CHDCT2 PF08074.11 RUS78401.1 - 0.61 10.2 7.1 4.3 7.5 6.9 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain AKNA PF12443.8 RUS78401.1 - 0.62 10.8 9.4 16 6.2 1.8 3.4 1 1 2 3 3 3 0 AT-hook-containing transcription factor DUF4140 PF13600.6 RUS78401.1 - 0.67 10.4 16.8 2.9 8.4 6.4 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CbiX PF01903.17 RUS78401.1 - 0.72 10.2 5.0 2.4 8.5 1.1 2.4 1 1 1 2 2 2 0 CbiX TSNAXIP1_N PF15739.5 RUS78401.1 - 0.72 10.3 13.9 1.6e+03 -0.5 13.9 2.8 1 1 0 1 1 0 0 Translin-associated factor X-interacting N-terminus GCN5L1 PF06320.13 RUS78401.1 - 0.74 10.0 11.4 3.1 8.0 8.2 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Tnp_22_trimer PF17489.2 RUS78401.1 - 0.75 9.8 15.3 0.56 10.2 0.3 3.8 1 1 4 5 5 5 0 L1 transposable element trimerization domain TPD52 PF04201.15 RUS78401.1 - 0.77 9.4 15.3 1.8 8.1 0.7 2.9 1 1 1 2 2 2 0 Tumour protein D52 family Med4 PF10018.9 RUS78401.1 - 0.81 9.3 16.8 4.1 7.0 5.3 2.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Cnn_1N PF07989.11 RUS78401.1 - 0.87 9.8 13.5 9.1 6.5 4.3 3.0 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 CorA PF01544.18 RUS78401.1 - 0.9 8.8 8.0 1.9 7.7 8.0 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CCDC53 PF10152.9 RUS78401.1 - 0.97 9.8 11.3 15 5.9 0.8 2.9 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Rota_NSP3 PF01665.16 RUS78401.1 - 0.99 8.5 2.7 8.8 5.4 1.7 2.3 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 DUF4337 PF14235.6 RUS78401.1 - 1 9.5 4.0 12 6.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) SHE3 PF17078.5 RUS78401.1 - 1.1 8.9 11.1 3.3 7.4 4.7 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF641 PF04859.12 RUS78401.1 - 1.2 9.5 14.9 2.3 8.6 8.5 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spectrin PF00435.21 RUS78401.1 - 1.2 9.6 12.7 2.3 8.7 7.4 2.3 1 1 1 2 2 2 0 Spectrin repeat EMP24_GP25L PF01105.24 RUS78401.1 - 1.4 8.8 13.8 2.2 8.2 5.3 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Filo_VP35 PF02097.15 RUS78401.1 - 1.4 7.9 8.3 2.6 7.0 1.5 2.2 1 1 1 2 2 2 0 Filoviridae VP35 BST2 PF16716.5 RUS78401.1 - 1.6 9.4 17.7 9.4 6.9 8.6 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TPR_MLP1_2 PF07926.12 RUS78401.1 - 1.7 8.7 15.3 11 6.1 15.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 RUS78401.1 - 1.8 9.0 14.1 3.3 8.1 13.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Snf7 PF03357.21 RUS78401.1 - 1.8 8.1 11.4 7.5 6.1 11.3 1.9 1 1 0 1 1 1 0 Snf7 DUF745 PF05335.13 RUS78401.1 - 1.8 8.2 9.7 2.3 7.9 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PEARLI-4 PF05278.12 RUS78401.1 - 1.9 8.0 12.2 0.62 9.6 2.0 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) MscS_porin PF12795.7 RUS78401.1 - 2 7.9 21.6 2.6 7.5 5.6 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF2076 PF09849.9 RUS78401.1 - 2.1 8.3 12.8 1.1 9.3 1.4 2.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) GrpE PF01025.19 RUS78401.1 - 2.1 8.0 8.1 5.8 6.5 2.6 2.3 1 1 1 2 2 2 0 GrpE COG5 PF10392.9 RUS78401.1 - 2.2 8.4 8.8 20 5.4 8.8 2.1 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 RUS78401.1 - 2.2 7.5 10.7 7.5 5.8 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 RUS78401.1 - 2.3 6.7 13.6 2.6 6.5 13.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF2951 PF11166.8 RUS78401.1 - 2.3 8.5 8.7 12 6.2 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) HAUS-augmin3 PF14932.6 RUS78401.1 - 3.4 7.2 15.2 20 4.7 14.9 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Cauli_AT PF03233.13 RUS78401.1 - 3.5 7.5 5.0 28 4.6 4.8 2.0 1 1 0 1 1 1 0 Aphid transmission protein GIT_CC PF16559.5 RUS78401.1 - 3.5 7.6 10.5 14 5.6 0.6 3.0 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_lid_9 PF17871.1 RUS78401.1 - 3.9 7.5 5.7 43 4.1 5.7 2.5 1 1 0 1 1 1 0 AAA lid domain DUF3086 PF11285.8 RUS78401.1 - 4.3 6.4 15.8 6.1 5.9 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3086) CtIP_N PF10482.9 RUS78401.1 - 4.6 7.3 20.4 17 5.5 2.6 2.5 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain KxDL PF10241.9 RUS78401.1 - 4.7 7.6 9.8 2.7 8.3 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein HMMR_N PF15905.5 RUS78401.1 - 5.5 6.4 18.1 7.2 6.0 12.9 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-H PF05837.12 RUS78401.1 - 6.3 7.3 15.3 51 4.3 14.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FliJ PF02050.16 RUS78401.1 - 6.9 6.9 19.0 11 6.2 15.4 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Vps5 PF09325.10 RUS78401.1 - 7.3 6.1 14.6 9 5.8 3.0 2.3 1 1 1 2 2 2 0 Vps5 C terminal like Angiomotin_C PF12240.8 RUS78401.1 - 7.5 6.0 21.5 16 5.0 7.7 1.9 1 1 1 2 2 2 0 Angiomotin C terminal WASH_WAHD PF11945.8 RUS78401.1 - 7.9 5.9 12.3 8.3e+02 -0.7 11.0 2.5 1 1 0 1 1 1 0 WAHD domain of WASH complex 5_nucleotid PF05761.14 RUS78401.1 - 7.9 5.3 8.2 18 4.0 8.2 1.6 1 1 0 1 1 1 0 5' nucleotidase family Med9 PF07544.13 RUS78401.1 - 8.9 6.5 14.9 17 5.6 1.9 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Wtap PF17098.5 RUS78401.1 - 9.2 6.2 16.2 6.6 6.7 10.9 2.1 1 1 1 2 2 2 0 WTAP/Mum2p family Spc29 PF17082.5 RUS78401.1 - 9.3 6.0 12.5 15 5.4 2.9 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF3847 PF12958.7 RUS78401.1 - 9.6 6.4 26.4 1.8e+04 -10.9 26.4 3.5 1 1 0 1 1 0 0 Protein of unknown function (DUF3847) hEGF PF12661.7 RUS78402.1 - 0.016 15.8 2.2 0.045 14.4 2.2 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_3 PF12947.7 RUS78402.1 - 0.021 15.0 0.2 0.039 14.1 0.2 1.4 1 0 0 1 1 1 0 EGF domain EGF_CA PF07645.15 RUS78402.1 - 0.7 10.2 3.7 2.5 8.4 3.7 1.9 1 1 0 1 1 1 0 Calcium-binding EGF domain INSC_LBD PF16748.5 RUS78403.1 - 7.7e-10 38.1 1.0 2.4e-09 36.5 1.0 1.7 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Arm PF00514.23 RUS78403.1 - 0.0001 22.2 9.4 0.7 10.0 0.0 6.0 6 2 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS78403.1 - 0.016 15.6 4.3 1.4 9.3 0.2 3.4 2 1 2 4 4 4 0 HEAT repeats Peptidase_M60 PF13402.6 RUS78403.1 - 0.052 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like HEAT_EZ PF13513.6 RUS78403.1 - 7.8 7.1 11.5 5.4 7.6 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat Brix PF04427.18 RUS78404.1 - 1.2e-41 142.9 0.7 1.8e-41 142.4 0.0 1.6 2 0 0 2 2 2 1 Brix domain Ank_2 PF12796.7 RUS78405.1 - 2.8e-51 172.0 7.6 3.1e-10 40.5 0.1 5.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS78405.1 - 3.5e-45 151.4 15.0 1e-09 38.4 0.1 8.3 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS78405.1 - 1.3e-43 146.8 10.5 3e-09 37.3 0.0 9.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 RUS78405.1 - 1.6e-39 132.6 22.7 0.0003 21.1 0.0 10.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 RUS78405.1 - 3.7e-39 128.3 11.1 0.00044 20.5 0.0 11.4 11 0 0 11 11 11 8 Ankyrin repeat SOCS_box PF07525.16 RUS78405.1 - 4.7e-06 26.9 2.2 1.2e-05 25.6 2.2 1.7 1 0 0 1 1 1 1 SOCS box DDT PF02791.17 RUS78405.1 - 0.024 14.9 0.3 0.067 13.5 0.0 1.9 2 0 0 2 2 2 0 DDT domain ACT_5 PF13710.6 RUS78405.1 - 0.033 14.0 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 ACT domain TMEM135_C_rich PF15982.5 RUS78406.1 - 5.8e-10 39.9 1.1 9e-07 29.6 0.2 2.3 2 0 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 RUS78406.1 - 6.7e-05 23.2 0.4 0.00064 20.1 0.3 2.3 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family CitMHS PF03600.16 RUS78407.1 - 6.2e-05 22.3 5.9 6.9e-05 22.2 5.9 1.3 1 0 0 1 1 1 1 Citrate transporter PHO4 PF01384.20 RUS78407.1 - 1.1 8.3 6.3 7.8 5.4 7.3 1.3 1 1 0 1 1 1 0 Phosphate transporter family TMEM135_C_rich PF15982.5 RUS78408.1 - 0.0042 17.7 3.2 0.0063 17.1 2.0 1.8 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 OKR_DC_1_N PF03709.15 RUS78409.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SASA PF03629.18 RUS78410.1 - 1.3e-12 47.8 0.0 2.6e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase 3HCDH_N PF02737.18 RUS78411.1 - 1.8e-44 151.8 0.0 2.8e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RUS78411.1 - 1.2e-13 51.5 0.1 2.4e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RUS78411.1 - 0.00033 20.8 0.0 0.00056 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 RUS78411.1 - 0.0042 16.5 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RUS78411.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 RUS78411.1 - 0.061 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 RUS78411.1 - 0.14 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PEX11 PF05648.14 RUS78412.1 - 6.3e-30 104.3 0.1 7.1e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) YccV-like PF08755.11 RUS78413.1 - 5.1e-29 100.7 0.4 8e-29 100.0 0.4 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like TPR_1 PF00515.28 RUS78414.1 - 2.5e-37 125.2 31.1 5e-08 32.4 0.1 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS78414.1 - 5.3e-37 122.9 23.3 3.2e-06 26.9 0.3 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 RUS78414.1 - 2.7e-34 114.5 26.1 6.7e-06 25.8 0.4 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 RUS78414.1 - 2.6e-31 108.0 10.4 1.3e-08 35.3 0.9 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat DUF1736 PF08409.11 RUS78414.1 - 5.9e-31 106.3 0.4 1.2e-30 105.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 RUS78414.1 - 9.3e-28 95.7 14.0 7.5e-08 31.9 1.1 7.7 5 2 2 7 7 7 5 TPR repeat TPR_12 PF13424.6 RUS78414.1 - 1.4e-24 86.1 21.1 4.4e-08 33.3 0.1 7.0 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 RUS78414.1 - 5.5e-19 67.2 14.8 0.0015 19.1 0.3 9.0 3 2 7 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 RUS78414.1 - 1.2e-18 65.7 7.7 0.068 13.2 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 RUS78414.1 - 5.6e-17 60.8 15.0 0.00063 19.9 0.4 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 RUS78414.1 - 8.1e-17 61.5 19.3 1.5e-05 25.4 0.7 6.2 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 RUS78414.1 - 1.5e-14 53.3 24.1 0.0011 18.7 0.1 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS78414.1 - 1.5e-08 34.8 10.9 0.0004 20.6 0.6 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RUS78414.1 - 8.1e-07 29.1 2.4 0.36 11.0 0.0 5.2 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS78414.1 - 3e-06 26.9 3.5 7.4e-05 22.3 0.0 3.1 1 1 2 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 RUS78414.1 - 3.4e-06 27.3 16.3 1.8 9.4 0.0 8.2 7 1 1 8 8 8 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RUS78414.1 - 0.0034 17.0 0.2 0.28 10.8 0.1 3.1 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 RUS78414.1 - 0.01 16.0 0.6 19 5.8 0.4 3.8 4 0 0 4 4 2 0 PPR repeat TPR_15 PF13429.6 RUS78414.1 - 0.017 14.3 12.1 0.41 9.8 3.9 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 RUS78414.1 - 0.028 13.3 8.2 3.6 6.4 0.5 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 RUS78414.1 - 0.033 14.2 11.7 0.2 11.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RUS78414.1 - 0.049 14.3 0.9 1e+02 4.0 0.0 5.7 8 0 0 8 8 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 RUS78414.1 - 0.057 12.8 4.3 0.84 9.0 1.4 2.6 2 1 1 3 3 3 0 Coatomer epsilon subunit TPR_20 PF14561.6 RUS78414.1 - 0.076 13.4 7.7 29 5.1 0.2 5.0 2 1 3 5 5 5 0 Tetratricopeptide repeat BHD_2 PF10404.9 RUS78414.1 - 0.11 13.5 0.0 0.28 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Wzy_C_2 PF11846.8 RUS78414.1 - 0.13 12.2 0.0 0.13 12.2 0.0 4.3 3 2 2 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal DUF3397 PF11877.8 RUS78414.1 - 0.67 10.2 8.1 0.07 13.3 2.7 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3397) MIT PF04212.18 RUS78414.1 - 9.5 6.4 12.0 5.5 7.1 0.0 5.1 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain adh_short PF00106.25 RUS78415.1 - 1.7e-32 112.4 0.1 1.2e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS78415.1 - 7.9e-22 78.0 0.0 8.3e-17 61.5 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS78415.1 - 2.8e-08 33.9 0.0 4.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 RUS78415.1 - 0.056 12.6 0.3 2 7.5 0.1 2.3 1 1 0 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 RUS78415.1 - 0.11 12.7 0.2 3.6 7.8 0.0 2.6 1 1 2 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HATPase_c PF02518.26 RUS78415.1 - 0.13 12.8 0.1 2.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_delta2 PF13177.6 RUS78416.1 - 9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 RUS78416.1 - 2.9e-07 30.6 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 RUS78416.1 - 1.4e-06 28.8 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 RUS78416.1 - 0.00025 21.4 0.0 0.00078 19.8 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain ATPgrasp_ST PF14397.6 RUS78416.1 - 0.00027 20.3 0.2 0.00071 18.9 0.2 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DNA_pol3_delta PF06144.13 RUS78416.1 - 0.00048 19.9 0.0 0.0016 18.3 0.0 1.7 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 RUS78416.1 - 0.0084 16.4 0.1 0.036 14.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RUS78416.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS78416.1 - 0.018 15.4 0.1 0.065 13.6 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 RUS78416.1 - 0.031 14.8 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter VWA_CoxE PF05762.14 RUS78416.1 - 0.046 13.1 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Prenyltransf PF01255.19 RUS78416.1 - 0.059 12.9 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Sigma54_activ_2 PF14532.6 RUS78416.1 - 0.064 13.4 0.1 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 RUS78416.1 - 0.076 12.8 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sel1 PF08238.12 RUS78417.1 - 2.4e-31 107.4 13.5 4.4e-11 43.1 0.0 7.0 7 1 0 7 7 7 3 Sel1 repeat TPR_6 PF13174.6 RUS78417.1 - 0.00017 22.0 9.2 2.4 9.0 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS78417.1 - 0.027 15.3 0.6 21 6.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS78417.1 - 0.25 11.9 3.5 0.59 10.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-met PF12874.7 RUS78419.1 - 1.1e-16 60.6 14.2 9.4e-07 29.0 2.4 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS78419.1 - 2.4e-08 34.0 10.4 0.0013 19.0 3.4 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS78419.1 - 0.00016 22.0 9.2 0.58 10.5 1.4 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 RUS78419.1 - 0.0021 17.8 13.4 0.24 11.2 2.5 3.6 3 0 0 3 3 3 2 U1 zinc finger zf-C2H2 PF00096.26 RUS78419.1 - 0.017 15.5 6.0 0.69 10.5 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ATP-synt_B PF00430.18 RUS78419.1 - 0.12 12.5 18.3 0.3 11.2 18.3 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) NPIP PF06409.11 RUS78419.1 - 0.95 8.5 7.0 2.4 7.1 7.0 1.7 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) zf-C2H2_4 PF13894.6 RUS78419.1 - 2 9.5 8.5 10 7.3 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4410 PF14366.6 RUS78419.1 - 5.5 6.9 7.4 16 5.4 7.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) zf-DBF PF07535.12 RUS78419.1 - 8.9 6.5 8.2 15 5.7 2.6 2.8 2 0 0 2 2 2 0 DBF zinc finger WD40 PF00400.32 RUS78420.1 - 1.5e-34 117.4 17.3 4.8e-07 30.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS78420.1 - 6.8e-17 61.6 1.9 0.00047 20.4 0.0 5.3 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS78420.1 - 6.6e-05 22.9 0.5 0.14 12.0 0.1 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.32 RUS78421.1 - 3.5e-08 32.4 12.6 8.1e-05 21.9 0.7 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS78421.1 - 1.5e-07 30.8 3.9 0.00075 19.2 1.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS78421.1 - 1.7e-07 31.6 1.2 1.7e-07 31.6 1.2 2.8 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS78421.1 - 0.00034 20.4 2.8 0.00084 19.1 1.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS78421.1 - 0.0016 18.7 0.3 0.0016 18.7 0.3 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 RUS78421.1 - 0.035 13.6 4.5 1.8 8.2 0.5 3.0 2 0 0 2 2 2 0 EF hand Beta-lactamase2 PF13354.6 RUS78421.1 - 0.046 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family CSN7a_helixI PF18392.1 RUS78422.1 - 8.7e-17 60.8 5.5 1.7e-16 59.8 5.5 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 RUS78422.1 - 7e-08 32.9 0.3 2e-07 31.5 0.3 1.7 1 1 0 1 1 1 1 PCI domain Unpaired PF15972.5 RUS78422.1 - 0.017 14.6 0.6 0.029 13.9 0.6 1.3 1 0 0 1 1 1 0 Unpaired protein Phage_pRha PF09669.10 RUS78422.1 - 0.039 14.5 0.5 0.078 13.5 0.5 1.4 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Mrpl_C PF18502.1 RUS78422.1 - 0.053 13.8 1.5 0.11 12.8 0.8 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain MqsA_antitoxin PF15731.5 RUS78422.1 - 0.13 12.3 0.9 0.22 11.6 0.9 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Trypsin_2 PF13365.6 RUS78423.1 - 7.3e-05 23.7 0.0 0.00018 22.4 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin_2 PF13365.6 RUS78424.1 - 7.9e-07 30.1 0.2 1.3e-06 29.4 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PKD_channel PF08016.12 RUS78425.1 - 9.5e-27 93.7 20.7 1.9e-26 92.7 20.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel TBK1_ULD PF18396.1 RUS78425.1 - 0.11 12.5 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PLAT PF01477.23 RUS78426.1 - 0.0052 17.3 0.0 0.0064 17.0 0.0 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain PDEase_II PF02112.15 RUS78429.1 - 6.9 5.7 9.7 9.4 5.2 2.2 2.3 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II MFS_1 PF07690.16 RUS78430.1 - 3.2e-25 88.8 35.4 9.6e-25 87.2 34.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2569 PF10754.9 RUS78430.1 - 6.7 7.1 6.7 0.62 10.5 1.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) DUF4573 PF15140.6 RUS78431.1 - 1.6e-17 63.9 2.8 2.4e-13 50.3 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4573) zf-Nse PF11789.8 RUS78431.1 - 8.6e-07 28.7 4.3 3.1 7.7 0.0 5.3 2 2 3 5 5 5 3 Zinc-finger of the MIZ type in Nse subunit STI1 PF17830.1 RUS78431.1 - 0.11 12.4 3.7 38 4.3 0.1 3.3 3 0 0 3 3 3 0 STI1 domain U-box PF04564.15 RUS78431.1 - 2.5 8.3 6.9 64 3.8 0.1 4.1 2 1 2 4 4 4 0 U-box domain Gp_dh_C PF02800.20 RUS78431.1 - 5.4 6.6 6.6 3.4 7.2 0.8 2.6 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Coilin_N PF15862.5 RUS78432.1 - 3.2e-13 49.7 2.6 3.2e-13 49.7 2.6 4.7 4 1 0 4 4 4 1 Coilin N-terminus Sulfatase PF00884.23 RUS78433.1 - 4.6e-64 216.7 1.1 5.7e-64 216.5 1.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 RUS78433.1 - 5.1e-05 24.0 0.0 0.00013 22.7 0.0 1.7 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 RUS78433.1 - 0.0009 18.9 0.2 0.54 9.8 0.2 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 RUS78433.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function Acyl-ACP_TE PF01643.17 RUS78434.1 - 2e-10 40.4 0.1 4.6e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS78434.1 - 0.08 13.4 0.0 11 6.5 0.0 2.6 2 1 0 2 2 2 0 Thioesterase-like superfamily DUF745 PF05335.13 RUS78435.1 - 0.0079 15.9 8.1 0.01 15.6 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Tape_meas_lam_C PF09718.10 RUS78435.1 - 0.047 13.8 0.2 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ADIP PF11559.8 RUS78435.1 - 0.22 11.6 11.0 0.32 11.1 11.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tmemb_9 PF05434.11 RUS78435.1 - 0.24 11.3 3.7 0.37 10.7 3.7 1.3 1 0 0 1 1 1 0 TMEM9 MFS_1 PF07690.16 RUS78436.1 - 6e-22 78.0 15.9 2.3e-21 76.1 15.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5381 PF17353.2 RUS78436.1 - 0.1 12.4 1.3 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Multi_Drug_Res PF00893.19 RUS78436.1 - 6.9 7.4 8.4 0.82 10.4 1.7 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein Thyroglobulin_1 PF00086.18 RUS78438.1 - 3.2e-27 94.0 17.8 7.4e-16 57.6 5.3 2.6 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 RUS78438.1 - 4.6e-13 49.5 0.1 1e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 RUS78438.1 - 3.2e-07 30.4 1.7 3.2e-07 30.4 1.7 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS78438.1 - 3.5e-06 26.9 1.6 3.5e-06 26.9 1.6 3.2 4 0 0 4 4 4 1 Kazal-type serine protease inhibitor domain NHL PF01436.21 RUS78439.1 - 0.055 13.5 0.8 5.8 7.1 0.0 3.5 4 0 0 4 4 4 0 NHL repeat zf-B_box PF00643.24 RUS78440.1 - 9.9e-09 35.2 15.7 0.00017 21.7 3.9 2.4 2 0 0 2 2 2 2 B-box zinc finger Phage_Gp15 PF06854.11 RUS78440.1 - 0.086 12.8 1.1 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage Gp15 protein FYVE_2 PF02318.16 RUS78440.1 - 0.62 10.3 18.5 0.91 9.8 3.9 2.9 3 0 0 3 3 3 0 FYVE-type zinc finger CEBP_ZZ PF16366.5 RUS78440.1 - 0.98 9.7 13.5 0.043 14.1 4.5 2.3 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FYVE PF01363.21 RUS78440.1 - 1.2 9.4 19.2 0.082 13.1 12.5 2.2 1 1 1 2 2 2 0 FYVE zinc finger Abhydrolase_3 PF07859.13 RUS78441.1 - 2.4e-55 187.6 0.0 4.7e-38 131.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 RUS78441.1 - 3.3e-06 26.3 0.3 0.00015 20.8 0.1 2.2 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS78441.1 - 2.3e-05 24.0 0.0 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS78441.1 - 7.4e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase_phd PF10503.9 RUS78441.1 - 0.0082 15.7 1.1 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 RUS78441.1 - 0.031 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme p450 PF00067.22 RUS78442.1 - 3.7e-66 223.8 0.0 4.9e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Leu_Phe_trans PF03588.14 RUS78442.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase 7tm_1 PF00001.21 RUS78443.1 - 1.9e-19 70.0 17.9 2.3e-19 69.7 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS78443.1 - 1.6e-08 34.2 19.0 8.1e-08 31.9 19.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw SP_C-Propep PF08999.10 RUS78443.1 - 1.3 8.9 4.6 15 5.4 1.6 2.7 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF5345 PF17280.2 RUS78443.1 - 9.5 6.3 0.0 9.5 6.3 0.0 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5345) Ion_trans PF00520.31 RUS78444.1 - 1.1e-06 28.0 3.4 1.5e-06 27.6 3.4 1.4 1 1 0 1 1 1 1 Ion transport protein VGPC1_C PF16799.5 RUS78444.1 - 0.016 15.1 0.8 0.041 13.9 0.8 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ABC_trans_CmpB PF06541.11 RUS78444.1 - 0.043 14.1 0.1 0.043 14.1 0.1 1.6 2 0 0 2 2 2 0 Putative ABC-transporter type IV DUF1570 PF07607.11 RUS78444.1 - 0.19 12.0 1.9 0.39 11.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) G-patch PF01585.23 RUS78445.1 - 3.6e-16 58.8 0.9 3.6e-16 58.8 0.9 1.9 2 0 0 2 2 2 1 G-patch domain FHA PF00498.26 RUS78445.1 - 1e-10 41.8 0.2 2.6e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 RUS78445.1 - 2.2e-06 27.7 0.1 2.2e-06 27.7 0.1 2.3 3 0 0 3 3 3 1 G-patch domain Yop-YscD_cpl PF16697.5 RUS78445.1 - 6.2e-05 23.2 0.1 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain YTH PF04146.15 RUS78445.1 - 0.086 12.8 1.7 0.17 11.8 1.7 1.4 1 0 0 1 1 1 0 YT521-B-like domain MADF_DNA_bdg PF10545.9 RUS78446.1 - 2.8e-11 43.6 0.1 9.7e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like FAR1 PF03101.15 RUS78446.1 - 0.011 16.4 0.1 0.022 15.4 0.1 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Inositol_P PF00459.25 RUS78447.1 - 8.4e-26 91.1 3.4 4e-25 88.9 3.4 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Ras PF00071.22 RUS78448.1 - 4.3e-54 182.5 0.4 5.1e-54 182.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78448.1 - 1.9e-19 70.1 0.0 3.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78448.1 - 4.1e-10 39.4 0.0 5.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS78448.1 - 4e-06 26.8 0.1 0.01 15.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS78448.1 - 8.2e-05 22.2 0.1 0.00042 19.9 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS78448.1 - 0.00088 19.3 0.1 0.0021 18.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 RUS78448.1 - 0.0032 17.1 0.1 0.014 15.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain Sacchrp_dh_NADP PF03435.18 RUS78448.1 - 0.018 15.3 0.1 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain EIAV_Rev PF11129.8 RUS78448.1 - 0.034 14.3 0.6 0.055 13.7 0.6 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus FeoB_N PF02421.18 RUS78448.1 - 0.057 13.0 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1353 PF07087.11 RUS78448.1 - 0.12 12.1 0.2 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Med1 PF10744.9 RUS78449.1 - 5e-42 144.4 2.5 5e-42 144.4 2.5 4.0 5 0 0 5 5 5 1 Mediator of RNA polymerase II transcription subunit 1 zf-DBF PF07535.12 RUS78450.1 - 1.9e-14 53.5 2.2 4.6e-14 52.3 2.2 1.7 1 0 0 1 1 1 1 DBF zinc finger Ig_3 PF13927.6 RUS78451.1 - 8.8e-19 67.9 0.0 1.5e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS78451.1 - 2.3e-14 53.2 0.0 4.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RUS78451.1 - 7.9e-12 45.3 0.1 2.1e-06 27.9 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 RUS78451.1 - 2.1e-09 37.4 0.0 0.0022 18.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS78451.1 - 3.1e-08 33.8 0.0 0.0078 16.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS78451.1 - 7.6e-07 28.6 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS78451.1 - 0.0057 16.7 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS78451.1 - 0.0063 16.9 0.0 0.25 11.8 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 RUS78451.1 - 0.053 13.9 0.1 6.2 7.3 0.0 3.0 2 2 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Det1 PF09737.9 RUS78452.1 - 6.9e-166 552.4 4.3 8.3e-166 552.1 4.3 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Fels1 PF05666.11 RUS78452.1 - 0.031 13.9 0.2 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Fels-1 Prophage Protein-like 7TM_GPCR_Srx PF10328.9 RUS78453.1 - 1.6e-05 24.7 19.8 3.7e-05 23.5 19.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS78453.1 - 4.5e-05 22.9 7.3 5.6e-05 22.6 7.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ECSCR PF15820.5 RUS78453.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.8 2 1 2 4 4 4 0 Endothelial cell-specific chemotaxis regulator PMP1_2 PF08114.11 RUS78453.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.4 3 0 0 3 3 3 0 ATPase proteolipid family DUF485 PF04341.12 RUS78453.1 - 2 8.4 6.5 1.9 8.5 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PfkB PF00294.24 RUS78454.1 - 3.1e-58 197.5 0.0 3.8e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NTPase_I-T PF01931.18 RUS78455.1 - 3.9e-09 36.5 0.0 6.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF5427 PF10310.9 RUS78455.1 - 0.31 9.9 2.0 0.67 8.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) HEV_ORF1 PF02444.16 RUS78455.1 - 2.4 8.8 9.2 0.2 12.2 2.1 2.5 2 1 1 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) DNApol_Exo PF18136.1 RUS78456.1 - 4.8e-100 334.3 0.0 1e-99 333.2 0.0 1.6 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 RUS78456.1 - 1.5e-53 182.2 0.0 2.6e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 RUS78456.1 - 0.0017 18.1 0.1 0.021 14.5 0.1 2.4 1 1 0 1 1 1 1 3'-5' exonuclease PRESAN PF09687.10 RUS78456.1 - 0.011 16.3 0.4 0.041 14.4 0.4 2.0 1 0 0 1 1 1 0 Plasmodium RESA N-terminal DNA_pol_B_2 PF03175.13 RUS78456.1 - 0.039 12.8 0.0 0.089 11.6 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Ribosomal_L35p PF01632.19 RUS78457.1 - 1.4e-07 31.9 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 CE2_N PF17996.1 RUS78458.1 - 0.029 14.4 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal PYRIN PF02758.16 RUS78458.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain MIP PF00230.20 RUS78459.1 - 8.1e-54 182.7 6.4 9.8e-54 182.5 6.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein 7tm_2 PF00002.24 RUS78460.1 - 3e-32 111.8 9.1 3.6e-32 111.6 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cytochrom_B561 PF03188.16 RUS78460.1 - 0.012 15.7 3.3 8.9 6.4 0.2 3.2 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 7tm_1 PF00001.21 RUS78461.1 - 1.3e-45 155.8 9.2 1.8e-45 155.4 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78461.1 - 1.7e-06 27.9 7.4 1.7e-06 27.9 7.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS78461.1 - 4e-06 26.3 14.0 0.00019 20.8 0.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS78461.1 - 1.5e-05 24.5 10.0 2.1e-05 24.0 10.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS78461.1 - 0.00039 20.2 6.7 0.001 18.9 5.1 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF4231 PF14015.6 RUS78461.1 - 0.56 10.7 2.3 31 5.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Tmemb_cc2 PF10267.9 RUS78461.1 - 8.6 5.4 5.1 16 4.5 5.1 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein 7tm_1 PF00001.21 RUS78462.1 - 1.5e-40 139.2 17.8 1.8e-40 138.9 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS78462.1 - 3.8e-06 26.5 6.9 6.2e-06 25.8 6.9 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 RUS78462.1 - 4.2e-06 26.3 13.7 6.3e-06 25.8 13.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS78462.1 - 2.7e-05 23.9 13.1 2.7e-05 23.9 13.1 2.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS78462.1 - 0.0011 18.7 9.9 0.0011 18.7 9.9 2.3 2 1 0 2 2 2 1 Olfactory receptor ANAPC4_WD40 PF12894.7 RUS78465.1 - 0.009 16.3 1.8 2.6 8.4 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AA_kinase PF00696.28 RUS78466.1 - 3.7e-28 98.7 0.2 1.2e-27 97.1 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.22 RUS78466.1 - 7.9e-17 60.9 0.3 1e-11 44.0 0.1 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family ACT_6 PF13740.6 RUS78466.1 - 0.061 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 ACT domain PDH PF02153.17 RUS78466.1 - 0.091 11.8 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase LETM1 PF07766.13 RUS78467.1 - 4.7e-97 324.5 6.9 4.7e-97 324.5 6.9 2.8 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 RUS78467.1 - 1.4e-05 25.4 5.2 0.0026 18.2 0.4 3.7 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS78467.1 - 3.4e-05 23.1 0.2 0.0029 17.0 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS78467.1 - 5.1e-05 22.9 0.2 0.078 13.0 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain LOH1CR12 PF10158.9 RUS78467.1 - 0.012 15.6 0.4 0.012 15.6 0.4 3.2 4 1 0 4 4 4 0 Tumour suppressor protein EF-hand_8 PF13833.6 RUS78467.1 - 0.023 14.5 0.9 0.14 12.0 0.3 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS78467.1 - 0.034 13.7 0.4 0.13 11.8 0.4 2.1 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 RUS78467.1 - 0.055 13.8 0.6 4.6 7.6 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Pkinase PF00069.25 RUS78468.1 - 6e-75 252.0 0.0 7.8e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78468.1 - 2.4e-36 125.4 0.0 3.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS78468.1 - 1.3e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS78468.1 - 1.5e-05 24.5 1.1 3e-05 23.5 0.4 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS78468.1 - 0.0005 19.7 0.4 0.001 18.7 0.4 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 RUS78468.1 - 0.0046 16.5 0.1 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 RUS78468.1 - 0.12 12.0 0.1 6.1 6.4 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS78468.1 - 0.14 12.1 0.0 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSP70 PF00012.20 RUS78470.1 - 3.6e-110 368.9 0.5 4.3e-110 368.7 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS78470.1 - 4.9e-14 51.9 0.5 2.5e-13 49.6 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 RUS78470.1 - 0.0024 17.1 0.1 0.0055 16.0 0.1 1.8 1 1 0 1 1 1 1 StbA protein DDR PF08841.10 RUS78470.1 - 0.0065 15.5 0.0 0.094 11.7 0.0 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain TPP_enzyme_N PF02776.18 RUS78470.1 - 0.092 12.4 0.2 0.52 9.9 0.1 2.2 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Raco_middle PF17651.1 RUS78470.1 - 0.13 12.0 0.6 15 5.2 0.0 2.9 3 0 0 3 3 3 0 RACo middle region Profilin PF00235.19 RUS78471.1 - 0.00021 21.5 0.0 0.00087 19.6 0.0 2.0 2 0 0 2 2 2 1 Profilin Plasmodium_HRP PF05403.11 RUS78472.1 - 3e-05 23.9 6.2 6.5e-05 22.8 6.2 1.5 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) DUF4239 PF14023.6 RUS78474.1 - 0.0015 18.3 1.1 0.0024 17.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Trypan_PARP PF05887.11 RUS78474.1 - 0.58 10.1 112.0 5.8e+02 0.4 15.9 4.4 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Promethin PF16015.5 RUS78474.1 - 6.6 6.7 10.0 0.17 11.8 2.2 2.1 2 0 0 2 2 2 0 Promethin Reeler PF02014.16 RUS78475.1 - 7e-27 94.7 0.0 9.9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Reeler domain Reeler PF02014.16 RUS78476.1 - 5.7e-26 91.8 0.0 7.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Reeler domain Poxvirus_B22R_N PF13169.6 RUS78477.1 - 8.1e-05 23.0 0.8 57 4.3 0.0 4.9 1 1 2 5 5 5 0 Poxvirus B22R protein N-terminal DUF4041 PF13250.6 RUS78477.1 - 0.00085 19.1 0.5 10 6.1 0.0 4.4 2 1 4 6 6 6 1 Domain of unknown function (DUF4041) DUF2247 PF10004.9 RUS78477.1 - 0.0013 18.5 11.0 27 4.5 0.1 5.9 1 1 6 7 7 7 1 Uncharacterized protein conserved in bacteria (DUF2247) IstB_IS21 PF01695.17 RUS78477.1 - 0.0022 17.8 2.6 19 4.9 0.1 3.5 1 1 5 6 6 6 5 IstB-like ATP binding protein T6SS_HCP PF05638.12 RUS78477.1 - 0.015 15.7 3.8 20 5.6 0.3 3.6 1 1 2 3 3 3 0 Type VI secretion system effector, Hcp AAA_assoc PF14363.6 RUS78477.1 - 0.28 11.6 2.1 20 5.6 0.0 3.7 2 1 1 3 3 3 0 Domain associated at C-terminal with AAA F-box PF00646.33 RUS78478.1 - 1.2e-11 44.2 0.3 3.5e-11 42.7 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS78478.1 - 2e-09 37.2 0.8 5e-09 35.9 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 RUS78478.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 F-box KN17_SH3 PF18131.1 RUS78479.1 - 7.1e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain PEHE PF15275.6 RUS78480.1 - 5.9e-20 72.2 3.2 5.9e-20 72.2 3.2 3.3 2 1 1 3 3 3 1 PEHE domain MSL1_dimer PF16801.5 RUS78480.1 - 0.00097 18.8 6.8 0.0028 17.4 6.8 1.8 1 0 0 1 1 1 1 Dimerisation domain of Male-specific-Lethal 1 MPS2 PF17060.5 RUS78480.1 - 0.25 10.6 8.1 0.4 9.9 8.1 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 WD40 PF00400.32 RUS78481.1 - 1.5e-31 107.9 24.0 1.9e-07 31.7 0.4 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 RUS78481.1 - 3.5e-17 62.7 0.1 6.2e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 RUS78481.1 - 1.4e-05 25.3 7.0 0.17 12.2 0.2 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS78481.1 - 0.012 14.3 8.0 1.2 7.7 2.8 3.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 RUS78481.1 - 0.023 14.8 0.3 4.6 7.3 0.0 3.9 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Gmad1 PF10647.9 RUS78481.1 - 2.3 7.9 7.2 2.7 7.7 1.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Lipase_GDSL PF00657.22 RUS78483.1 - 0.0029 17.6 0.0 0.0066 16.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Mitofilin PF09731.9 RUS78484.1 - 1.4e-125 420.6 32.5 1.8e-125 420.2 32.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ig_3 PF13927.6 RUS78485.1 - 4.7e-31 107.2 1.7 2.1e-14 53.9 0.3 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS78485.1 - 1.3e-25 89.3 0.0 7.5e-10 38.7 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS78485.1 - 4.1e-19 68.7 0.2 3.2e-08 33.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS78485.1 - 2.6e-16 59.6 0.2 0.00014 22.0 0.1 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS78485.1 - 9e-15 54.8 0.6 0.00014 22.0 0.1 3.9 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS78485.1 - 0.01 15.4 0.0 4.2 7.0 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS78485.1 - 0.011 15.7 0.2 7.7 6.6 0.0 3.4 3 1 0 3 3 3 0 C17orf99 Ig domain Izumo-Ig PF16706.5 RUS78485.1 - 0.013 15.5 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS78485.1 - 0.04 14.3 0.0 2.6 8.5 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Cyt-b5 PF00173.28 RUS78486.1 - 1.6e-10 41.0 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Actin PF00022.19 RUS78487.1 - 3.7e-110 368.3 0.0 3e-109 365.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RUS78487.1 - 0.15 10.8 0.0 6.7 5.4 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein RGS_DHEX PF18148.1 RUS78488.1 - 3.5e-48 161.8 0.8 1.1e-47 160.2 0.8 1.9 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 RUS78488.1 - 1e-32 112.9 0.3 1e-32 112.9 0.3 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 RUS78488.1 - 1e-16 60.7 0.0 3.2e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 RUS78488.1 - 1.6e-11 44.0 0.0 5.2e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 RUS78488.1 - 0.00012 21.8 0.3 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain Transposase_1 PF01359.18 RUS78489.1 - 6.7e-19 67.5 0.0 1.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS78489.1 - 6.8e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS78489.1 - 5e-05 23.5 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS78489.1 - 0.00057 20.4 0.6 0.0024 18.4 0.1 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS78489.1 - 0.0059 16.7 0.0 0.0059 16.7 0.0 2.5 3 0 0 3 3 3 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS78489.1 - 0.019 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS78489.1 - 0.05 13.2 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 RUS78489.1 - 0.081 13.4 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 PCI domain DUF4817 PF16087.5 RUS78489.1 - 0.093 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS78489.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS78489.1 - 0.12 11.8 0.0 0.39 10.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 EMP24_GP25L PF01105.24 RUS78490.1 - 6.3e-22 78.4 0.0 7.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Consortin_C PF15281.6 RUS78492.1 - 1.2 9.1 5.8 0.33 11.0 1.3 2.3 2 0 0 2 2 2 0 Consortin C-terminus PMT_4TMC PF16192.5 RUS78492.1 - 5.5 6.5 7.9 0.93 9.0 0.2 2.7 1 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase ADP_PFK_GK PF04587.15 RUS78494.1 - 1.4e-136 455.5 0.0 1.6e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region ER PF01133.17 RUS78495.1 - 1.8e-44 149.7 0.3 2e-44 149.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_M49 PF03571.15 RUS78497.1 - 3.8e-234 778.2 0.0 4.6e-234 777.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 CDC45 PF02724.14 RUS78499.1 - 0.0028 16.0 3.3 0.003 15.9 3.3 1.0 1 0 0 1 1 1 1 CDC45-like protein p450 PF00067.22 RUS78500.1 - 6.6e-104 348.2 0.0 8.3e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wzy_C PF04932.15 RUS78500.1 - 0.086 12.5 4.7 0.2 11.3 4.4 1.8 2 0 0 2 2 2 0 O-Antigen ligase p450 PF00067.22 RUS78501.1 - 1.8e-104 350.1 0.0 2.2e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS78502.1 - 8.8e-94 314.8 0.0 1.1e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.13 RUS78503.1 - 3.8e-13 49.9 19.2 3.8e-13 49.9 19.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM18 PF14770.6 RUS78503.1 - 1.4 9.0 5.7 0.22 11.5 1.5 1.8 2 0 0 2 2 2 0 Transmembrane protein 18 Kelch_1 PF01344.25 RUS78504.1 - 2e-57 190.5 8.8 2.6e-13 49.3 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS78504.1 - 1.1e-38 130.3 7.5 2.9e-08 33.7 0.1 6.7 3 3 3 6 6 6 6 Kelch motif BTB PF00651.31 RUS78504.1 - 1.6e-31 108.8 1.5 2.5e-31 108.2 0.5 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS78504.1 - 1.6e-25 89.2 3.4 1.8e-25 89.0 1.7 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 RUS78504.1 - 1.1e-24 85.4 0.5 4.2e-06 26.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 RUS78504.1 - 4.1e-19 68.1 7.1 0.0055 16.7 0.2 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 RUS78504.1 - 9.5e-18 64.0 6.3 0.0031 17.8 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS78504.1 - 4.6e-16 58.6 6.3 2e-05 24.5 0.0 6.6 6 2 1 7 7 7 4 Galactose oxidase, central domain BTB_3 PF16017.5 RUS78504.1 - 0.035 14.2 0.1 0.084 13.0 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 RUS78505.1 - 5.4e-12 45.4 3.2 1.4e-11 44.1 2.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS78505.1 - 2.2e-10 40.2 4.6 2.2e-10 40.2 4.6 2.9 3 1 1 4 4 4 1 F-box domain LRR_6 PF13516.6 RUS78505.1 - 0.00031 20.6 2.4 40 4.6 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 RUS78505.1 - 0.012 16.0 7.8 2.3 8.7 0.1 5.5 3 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS78505.1 - 0.038 13.7 2.0 1.1 9.0 0.1 3.5 3 1 1 4 4 4 0 Leucine rich repeat CobD_Cbib PF03186.13 RUS78505.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 CobD/Cbib protein LRR_1 PF00560.33 RUS78505.1 - 2.7 8.9 5.7 1.1e+02 3.9 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat PK_C PF02887.16 RUS78507.1 - 2.1e-29 102.1 0.4 3.3e-29 101.5 0.4 1.3 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain PK PF00224.21 RUS78507.1 - 8.4e-24 84.1 0.3 1.1e-23 83.7 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain TrkA_N PF02254.18 RUS78507.1 - 0.053 13.8 0.4 0.11 12.7 0.3 1.6 1 1 0 1 1 1 0 TrkA-N domain Complex1_49kDa PF00346.19 RUS78508.1 - 1.1e-126 421.5 0.0 1.4e-126 421.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 RUS78508.1 - 0.0031 16.5 0.0 0.0065 15.4 0.0 1.5 2 0 0 2 2 2 1 Nickel-dependent hydrogenase LRR_8 PF13855.6 RUS78509.1 - 0.038 13.8 0.1 0.09 12.6 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat Rod_C PF10493.9 RUS78512.1 - 7.6e-22 77.4 0.2 1e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 Rough deal protein C-terminal region Telomere_Sde2_2 PF13297.6 RUS78512.1 - 0.093 12.4 0.0 22 4.8 0.0 2.6 2 0 0 2 2 2 0 Telomere stability C-terminal OAD_gamma PF04277.13 RUS78513.1 - 0.0052 17.3 0.2 0.011 16.3 0.0 1.6 2 0 0 2 2 1 1 Oxaloacetate decarboxylase, gamma chain TMEM52 PF14979.6 RUS78513.1 - 0.015 15.3 1.1 0.026 14.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 TMEM154 PF15102.6 RUS78513.1 - 0.015 15.2 0.6 0.015 15.2 0.6 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF4746 PF15928.5 RUS78513.1 - 0.017 14.6 0.2 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Shisa PF13908.6 RUS78513.1 - 0.039 14.2 5.2 0.034 14.4 3.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SIT PF15330.6 RUS78513.1 - 0.052 14.0 0.7 0.07 13.6 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Sigma_reg_N PF13800.6 RUS78513.1 - 0.1 12.9 1.0 0.23 11.8 1.0 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ECSCR PF15820.5 RUS78513.1 - 0.11 12.3 0.8 0.21 11.4 0.8 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF3377 PF11857.8 RUS78513.1 - 0.68 9.9 3.9 1.7 8.6 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4713 PF15831.5 RUS78513.1 - 0.93 10.0 9.3 1.4 9.4 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Tmemb_9 PF05434.11 RUS78513.1 - 1.1 9.1 4.0 0.21 11.5 0.4 1.6 2 0 0 2 2 2 0 TMEM9 CD34_antigen PF06365.12 RUS78513.1 - 1.4 8.5 4.5 0.57 9.7 1.2 1.8 2 0 0 2 2 2 0 CD34/Podocalyxin family HemY_N PF07219.13 RUS78513.1 - 1.6 9.0 4.8 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 HemY protein N-terminus Prominin PF05478.11 RUS78513.1 - 2.4 6.0 6.2 3.1 5.6 6.2 1.1 1 0 0 1 1 1 0 Prominin Comm PF15957.5 RUS78513.1 - 3.5 8.0 5.8 4.3 7.7 5.8 1.5 1 1 0 1 1 1 0 Commissureless DUF3139 PF11337.8 RUS78513.1 - 5.7 7.7 7.9 6.5 7.5 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Insulin_TMD PF17870.1 RUS78513.1 - 7.4 6.7 10.0 14 5.8 10.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ig_3 PF13927.6 RUS78514.1 - 1.5e-80 265.8 21.5 4e-14 53.0 0.4 7.1 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 RUS78514.1 - 1.1e-61 204.9 0.0 6.2e-09 35.8 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS78514.1 - 8.2e-59 195.9 13.1 5e-10 39.6 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 RUS78514.1 - 3.5e-51 171.3 12.1 2.8e-08 33.8 0.2 7.5 7 1 0 7 7 7 7 Immunoglobulin domain V-set PF07686.17 RUS78514.1 - 1.3e-36 125.1 14.6 1e-05 25.7 0.0 10.5 7 4 0 7 7 7 7 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS78514.1 - 3e-14 52.3 0.1 0.28 10.8 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin domain Izumo-Ig PF16706.5 RUS78514.1 - 3.2e-13 49.5 0.1 0.23 11.6 0.0 7.0 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS78514.1 - 1.5e-08 34.9 0.0 0.57 10.6 0.0 5.8 7 0 0 7 7 6 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 RUS78514.1 - 6.5e-08 32.9 0.0 3.4 8.1 0.0 7.7 7 5 0 7 7 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 RUS78514.1 - 2.1e-07 30.8 3.2 0.028 14.5 0.0 6.2 7 0 0 7 7 7 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 RUS78514.1 - 2.7e-07 30.7 0.4 0.7 10.1 0.0 4.8 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Ig_4 PF16680.5 RUS78514.1 - 0.00011 22.4 1.0 32 4.9 0.0 7.0 8 3 0 8 8 8 0 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 RUS78514.1 - 0.00043 20.3 7.4 0.04 14.0 0.2 5.5 6 1 0 6 6 6 1 CD80-like C2-set immunoglobulin domain AIRC PF00731.20 RUS78514.1 - 0.94 9.1 3.7 0.59 9.7 0.1 2.1 2 0 0 2 2 2 0 AIR carboxylase Ig_3 PF13927.6 RUS78515.1 - 1.6e-20 73.5 0.8 3.5e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS78515.1 - 6.7e-14 51.7 0.0 1.2e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS78515.1 - 2.1e-13 50.4 0.5 1.4e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS78515.1 - 5.7e-13 48.9 0.1 3.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS78515.1 - 4.3e-08 33.3 0.1 1.4e-05 25.3 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS78515.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 RUS78516.1 - 8.5e-15 55.1 0.1 1.1e-14 54.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS78516.1 - 2.1e-09 37.4 0.1 3e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS78516.1 - 2.2e-09 37.3 0.3 4.6e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 RUS78516.1 - 1.3e-07 31.7 0.2 1.6e-05 25.0 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS78516.1 - 2.5e-07 30.9 0.1 2.5e-07 30.9 0.1 1.5 2 0 0 2 2 2 1 Immunoglobulin domain VCBS PF13517.6 RUS78517.1 - 1.6e-06 28.6 2.9 0.079 13.6 0.3 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 RUS78517.1 - 0.0042 16.5 0.3 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 EF hand PQQ PF01011.21 RUS78517.1 - 0.0043 16.9 0.0 0.27 11.2 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat EF-hand_1 PF00036.32 RUS78517.1 - 0.017 14.6 0.2 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 EF hand FG-GAP PF01839.23 RUS78517.1 - 0.019 15.1 5.0 0.019 15.1 5.0 4.2 4 0 0 4 4 4 0 FG-GAP repeat PQQ_2 PF13360.6 RUS78517.1 - 0.037 13.6 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain TcdB_toxin_midN PF12256.8 RUS78517.1 - 0.096 12.0 0.1 0.55 9.6 0.0 2.3 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region EF-hand_6 PF13405.6 RUS78517.1 - 0.14 12.2 0.2 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Biotin_carb_N PF00289.22 RUS78518.1 - 0.022 15.3 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain AT_hook PF02178.19 RUS78519.1 - 7.3 6.8 8.0 0.19 11.7 1.4 2.0 2 0 0 2 2 2 0 AT hook motif Glyco_hydro_35 PF01301.19 RUS78520.1 - 7.6e-38 130.9 0.1 8.7e-38 130.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 EHN PF06441.12 RUS78520.1 - 0.015 15.6 0.5 0.029 14.8 0.3 1.6 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Ras PF00071.22 RUS78522.1 - 1.7e-61 206.6 0.1 1.9e-61 206.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78522.1 - 4.9e-35 120.4 0.0 8.4e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78522.1 - 5.8e-12 45.4 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS78522.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS78522.1 - 0.00024 21.0 0.2 0.38 10.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS78522.1 - 0.00034 20.7 0.0 0.00054 20.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS78522.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RUS78522.1 - 0.02 15.3 0.1 0.034 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RUS78522.1 - 0.068 13.5 0.1 1.5 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain MCR_beta PF02241.18 RUS78522.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Ank_2 PF12796.7 RUS78525.1 - 1.1e-21 77.2 0.0 5.7e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS78525.1 - 2.9e-20 72.0 0.3 0.00034 20.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78525.1 - 1e-18 65.4 0.0 0.00043 20.5 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 RUS78525.1 - 1.1e-16 60.4 0.1 0.01 16.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 RUS78525.1 - 9.4e-16 58.0 0.0 1.6e-05 25.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS78526.1 - 7.8e-19 68.1 0.6 9.9e-08 32.5 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78526.1 - 1.9e-12 47.4 0.4 0.01 16.4 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78526.1 - 5.1e-12 44.9 4.8 0.0044 17.4 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 RUS78526.1 - 4.8e-08 33.1 4.2 0.042 14.2 0.2 5.5 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS78526.1 - 6.3e-08 32.7 7.8 0.034 14.6 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeat DUF4816 PF16086.5 RUS78527.1 - 4.5 7.3 38.5 1.8e+04 -26.5 38.5 6.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) AIPR PF10592.9 RUS78529.1 - 4 7.0 7.9 4 7.0 0.9 2.3 2 0 0 2 2 2 0 AIPR protein DUF445 PF04286.12 RUS78529.1 - 4.4 7.0 10.6 6.7 6.4 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) TPP_enzyme_N PF02776.18 RUS78530.1 - 0.0032 17.1 0.1 0.026 14.2 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain I-set PF07679.16 RUS78531.1 - 2.6e-47 158.8 0.0 2e-16 59.8 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS78531.1 - 1e-29 102.9 0.0 2e-09 37.9 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain RhoGEF PF00621.20 RUS78531.1 - 2.5e-23 83.2 0.2 4.7e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain ig PF00047.25 RUS78531.1 - 1.2e-19 70.2 0.0 1.5e-06 28.3 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS78531.1 - 3.4e-19 69.0 0.0 1.2e-06 28.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain SH3_2 PF07653.17 RUS78531.1 - 2.9e-08 33.3 0.0 0.00011 21.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain C2-set_2 PF08205.12 RUS78531.1 - 3.5e-06 27.0 0.0 2.3 8.4 0.0 4.0 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RUS78531.1 - 5.9e-06 26.5 0.0 3.5 7.9 0.0 4.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS78531.1 - 4.2e-05 23.9 0.0 1.5 9.3 0.0 4.6 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 RUS78531.1 - 0.002 18.3 2.6 1.5 9.1 0.0 5.4 4 2 1 5 5 5 1 Immunoglobulin V-set domain SH3_9 PF14604.6 RUS78531.1 - 0.012 15.5 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain PH PF00169.29 RUS78531.1 - 0.041 14.4 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 PH domain SH3_3 PF08239.11 RUS78531.1 - 0.072 13.4 0.0 0.7 10.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain I-set PF07679.16 RUS78532.1 - 9.5e-25 86.5 3.3 2.4e-18 66.0 0.2 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS78532.1 - 7e-17 61.8 0.1 3.1e-11 43.7 0.2 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS78532.1 - 1.1e-08 35.2 0.1 1.3e-07 31.8 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS78532.1 - 2.8e-07 30.6 3.3 0.001 19.2 0.4 3.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS78532.1 - 0.018 15.2 0.5 1.3 9.2 0.5 3.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain I-set PF07679.16 RUS78534.1 - 2.7e-29 101.1 0.0 4.1e-18 65.2 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS78534.1 - 2.8e-20 72.7 0.0 4.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS78534.1 - 1.8e-13 50.6 0.0 8.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS78534.1 - 1.7e-10 40.9 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS78534.1 - 2e-08 34.2 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RUS78534.1 - 5.1e-06 26.8 0.0 0.051 14.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain V-set PF07686.17 RUS78534.1 - 0.00025 21.2 0.0 0.27 11.4 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS78534.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain BiPBP_C PF06832.12 RUS78534.1 - 0.15 12.1 0.0 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family I-set PF07679.16 RUS78535.1 - 5.1e-16 58.5 0.0 1.1e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS78535.1 - 3.7e-07 30.7 0.0 1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS78535.1 - 0.00092 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS78535.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain PAD_M PF08527.10 RUS78535.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain fn3 PF00041.21 RUS78536.1 - 2.8e-31 107.7 8.3 8.8e-09 35.6 0.0 4.9 4 1 0 4 4 4 4 Fibronectin type III domain Tissue_fac PF01108.17 RUS78536.1 - 8.7e-06 25.5 0.0 5.6 6.9 0.0 4.3 4 0 0 4 4 4 3 Tissue factor Pur_ac_phosph_N PF16656.5 RUS78536.1 - 0.00028 21.4 1.6 1 10.0 0.0 4.3 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS78536.1 - 0.032 14.6 0.0 10 6.5 0.0 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 RUS78537.1 - 6e-113 369.4 42.6 1.6e-11 44.4 0.1 13.1 13 0 0 13 13 12 12 Fibronectin type III domain Pkinase PF00069.25 RUS78537.1 - 3.2e-88 295.5 0.0 1.5e-49 168.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 RUS78537.1 - 1e-46 156.9 0.0 1.4e-17 63.5 0.0 5.7 5 0 0 5 5 5 3 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 RUS78537.1 - 2.5e-41 141.7 0.0 2.6e-23 82.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ig_3 PF13927.6 RUS78537.1 - 1.6e-28 99.1 0.1 6.3e-12 45.9 0.0 5.3 5 0 0 5 5 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS78537.1 - 2.4e-21 76.1 20.5 0.12 13.0 0.4 13.3 12 1 0 12 12 12 4 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 RUS78537.1 - 2.2e-18 66.1 0.1 0.38 10.6 0.0 10.1 11 0 0 11 11 11 5 Tissue factor Ig_2 PF13895.6 RUS78537.1 - 6.3e-17 61.7 0.0 2.4e-07 31.0 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS78537.1 - 1.9e-16 60.0 0.0 1.5e-06 28.3 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS78537.1 - 1e-07 32.1 0.0 0.00044 20.4 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin V-set domain PhoD_N PF16655.5 RUS78537.1 - 5e-07 30.2 12.8 25 5.5 0.0 11.5 13 0 0 13 13 13 0 PhoD-like phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS78537.1 - 7.8e-07 29.4 0.0 3.4 8.0 0.0 7.7 8 0 0 8 8 8 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 RUS78537.1 - 1.4e-05 25.4 1.9 47 4.5 0.0 7.5 8 0 0 8 8 7 0 Uncharacterised conserved protein (DUF2369) Ig_6 PF18452.1 RUS78537.1 - 0.0017 17.9 0.0 17 5.1 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain C2-set_2 PF08205.12 RUS78537.1 - 0.15 12.1 0.0 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain RAMA PF18755.1 RUS78538.1 - 1.7e-28 99.2 0.1 2.9e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated JAB PF01398.21 RUS78538.1 - 1.8e-10 40.8 0.0 6.3e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 RUS78538.1 - 8.6e-08 32.0 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Reprolysin_2 PF13574.6 RUS78539.1 - 2.7e-07 30.7 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS78539.1 - 3.2e-06 27.7 0.0 7.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS78539.1 - 3.3e-05 24.1 0.0 8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12 Pep_M12B_propep PF01562.19 RUS78539.1 - 0.00022 21.5 0.1 0.00039 20.7 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide DUF3597 PF12200.8 RUS78540.1 - 0.43 11.1 4.4 0.75 10.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) zf-C3HC4_2 PF13923.6 RUS78543.1 - 0.0058 16.4 0.6 0.01 15.7 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phage_gp53 PF11246.8 RUS78543.1 - 0.054 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Base plate wedge protein 53 RAG2_PHD PF13341.6 RUS78544.1 - 0.14 12.2 0.7 5.9 7.0 0.1 2.3 1 1 1 2 2 2 0 RAG2 PHD domain DSPc PF00782.20 RUS78545.1 - 6.4e-06 26.0 0.0 2.7e-05 24.0 0.0 2.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain p450 PF00067.22 RUS78546.1 - 2.4e-96 323.3 0.0 3.4e-96 322.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 eIF_4G1 PF12152.8 RUS78546.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 BRE PF06113.12 RUS78548.1 - 2e-80 270.0 0.1 2.4e-80 269.8 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) RRP36 PF06102.12 RUS78549.1 - 2.4e-39 135.0 30.4 3.4e-39 134.5 30.4 1.2 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 MWFE PF15879.5 RUS78549.1 - 0.21 11.8 0.0 0.53 10.5 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit EntA_Immun PF08951.10 RUS78549.1 - 0.55 10.6 5.5 0.16 12.4 1.3 2.2 2 0 0 2 2 2 0 Enterocin A Immunity Ureide_permease PF07168.11 RUS78549.1 - 2.3 6.9 4.6 3.1 6.5 4.6 1.3 1 0 0 1 1 1 0 Ureide permease KH_1 PF00013.29 RUS78551.1 - 3e-42 142.3 10.3 8.1e-14 51.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RUS78551.1 - 2.4e-10 40.1 5.4 0.0019 18.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RUS78551.1 - 0.00074 19.4 3.8 0.27 11.1 0.1 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 RUS78551.1 - 0.0048 17.0 5.6 4.1 7.5 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain adh_short PF00106.25 RUS78552.1 - 1.1e-44 152.3 0.0 1.4e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS78552.1 - 6e-26 91.4 0.0 7.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS78552.1 - 2.2e-08 34.2 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS78552.1 - 0.016 14.5 0.0 0.28 10.5 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 RUS78552.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 RUS78552.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Epimerase PF01370.21 RUS78552.1 - 0.065 12.7 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Spec3 PF15795.5 RUS78553.1 - 8.4e-23 80.7 12.5 1e-22 80.4 12.5 1.1 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein Transposase_1 PF01359.18 RUS78555.1 - 7.9e-07 28.8 0.1 1.7e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_48 PF17906.1 RUS78555.1 - 0.0015 18.6 0.3 0.0056 16.8 0.0 2.0 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 RUS78555.1 - 0.0044 17.6 0.0 0.015 15.9 0.0 2.0 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 RUS78555.1 - 0.0096 16.1 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS78555.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF4817 PF16087.5 RUS78555.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) GCIP PF13324.6 RUS78555.1 - 0.13 11.9 5.5 0.039 13.6 2.6 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 RUS78555.1 - 1.5 8.1 5.8 2.1 7.6 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RUS78555.1 - 5.2 6.7 6.5 7.6 6.2 6.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4207 PF13904.6 RUS78557.1 - 0.0016 18.2 37.1 0.0016 18.2 37.1 5.2 3 1 0 4 4 4 2 Domain of unknown function (DUF4207) BUD22 PF09073.10 RUS78558.1 - 0.0019 17.6 24.6 0.0024 17.3 24.6 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RUS78558.1 - 0.091 11.0 21.2 0.12 10.6 21.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2716 PF10898.8 RUS78558.1 - 0.099 13.0 0.3 0.17 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) CDC27 PF09507.10 RUS78558.1 - 3.4 7.0 21.5 2.7 7.3 20.0 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4532 PF15046.6 RUS78559.1 - 8e-26 90.8 2.1 1.6e-25 89.9 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4532) GNAT_acetyltr_2 PF13718.6 RUS78560.1 - 3.8e-100 334.0 0.0 5.6e-100 333.4 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 RUS78560.1 - 2.6e-63 213.1 0.0 5e-63 212.1 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 RUS78560.1 - 1.4e-32 111.5 1.3 1.5e-32 111.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 RUS78560.1 - 4.1e-14 52.9 0.5 8e-14 51.9 0.5 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.25 RUS78560.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS78560.1 - 0.026 15.0 0.1 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 RUS78560.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase tRNA_bind_2 PF13725.6 RUS78561.1 - 9.8e-48 162.9 2.7 9.8e-48 162.9 2.7 1.8 2 0 0 2 2 2 1 Possible tRNA binding domain Bac_DnaA_C PF08299.11 RUS78561.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix Med18 PF09637.10 RUS78562.1 - 4e-27 95.6 0.0 2.5e-23 83.2 0.0 2.0 1 1 0 1 1 1 1 Med18 protein zf-C2H2 PF00096.26 RUS78563.1 - 2.6e-17 62.2 43.8 3.8e-05 23.9 1.7 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78563.1 - 2.3e-14 53.1 13.9 2.9e-07 30.6 1.4 5.8 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78563.1 - 5e-14 51.8 41.8 0.018 15.8 1.3 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS78563.1 - 7.4e-07 29.0 24.2 0.00075 19.4 0.2 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 RUS78563.1 - 3.3e-06 27.3 33.0 0.13 12.7 1.6 6.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 RUS78563.1 - 0.071 13.9 11.5 0.76 10.6 0.7 3.3 2 1 0 3 3 3 0 zinc-ribbon family GAGA PF09237.11 RUS78563.1 - 0.18 11.6 2.4 4.4 7.2 0.5 2.8 1 1 2 3 3 3 0 GAGA factor TF_Zn_Ribbon PF08271.12 RUS78563.1 - 0.43 10.1 4.1 5 6.7 0.0 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Rtf2 PF04641.12 RUS78563.1 - 0.65 9.3 3.1 2 7.7 0.2 2.8 2 1 1 3 3 3 0 Rtf2 RING-finger zf-C2H2_jaz PF12171.8 RUS78563.1 - 1.1 9.6 28.5 4.8 7.6 0.4 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding QVR PF17064.5 RUS78564.1 - 0.0046 17.2 8.8 0.25 11.6 8.8 2.3 1 1 0 1 1 1 1 Sleepless protein zf-C2H2 PF00096.26 RUS78565.1 - 5.7e-12 45.4 42.7 3e-05 24.2 3.6 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78565.1 - 1e-11 44.7 28.1 1e-05 25.7 4.4 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78565.1 - 5.1e-06 26.9 40.1 0.011 16.5 2.8 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger Cript PF10235.9 RUS78565.1 - 0.0062 17.1 2.4 0.0062 17.1 2.4 3.2 2 1 1 3 3 3 1 Microtubule-associated protein CRIPT RNA_pol_Rpc4 PF05132.14 RUS78565.1 - 2.7 8.4 10.0 0.86 10.0 1.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 zf-met PF12874.7 RUS78565.1 - 5.3 7.6 24.3 0.74 10.3 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Roughex PF06020.11 RUS78565.1 - 9.8 5.2 12.3 0.054 12.6 3.4 1.7 2 0 0 2 2 2 0 Drosophila roughex protein PhyH PF05721.13 RUS78566.1 - 4.6e-33 115.3 0.0 6.4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 RUS78566.1 - 0.0019 19.1 0.1 0.0051 17.7 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 RUS78566.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 RUS78566.1 - 0.036 12.8 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) gerPA PF10676.9 RUS78568.1 - 0.23 11.7 6.0 2.9 8.2 0.2 3.1 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF STT3_PglB_C PF18527.1 RUS78568.1 - 0.42 10.8 1.5 20 5.4 0.0 3.5 4 0 0 4 4 4 0 STT3/PglB C-terminal beta-barrel domain DUF3665 PF12427.8 RUS78570.1 - 0.013 15.2 14.0 0.69 9.6 1.4 3.4 2 2 1 3 3 3 0 Branched-chain amino acid aminotransferase IFRD_C PF04836.12 RUS78570.1 - 0.18 12.4 12.3 16 6.2 1.1 3.5 2 1 1 3 3 3 0 Interferon-related protein conserved region DUF1651 PF07864.11 RUS78570.1 - 7.4 7.0 9.9 11 6.4 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1651) EGF PF00008.27 RUS78571.1 - 1.1e-16 60.8 41.1 4.3e-07 30.1 8.3 3.3 3 0 0 3 3 3 3 EGF-like domain EGF_CA PF07645.15 RUS78571.1 - 1.2e-08 35.0 42.4 0.0005 20.2 8.4 3.4 2 1 1 3 3 3 3 Calcium-binding EGF domain hEGF PF12661.7 RUS78571.1 - 5.8e-08 33.1 47.3 1.3e-05 25.7 6.7 4.2 5 0 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS78571.1 - 5.1e-05 23.6 52.5 0.0071 16.7 14.0 3.3 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 RUS78571.1 - 0.00067 19.8 7.0 0.00067 19.8 7.0 3.4 2 1 1 3 3 3 2 EGF domain cEGF PF12662.7 RUS78571.1 - 6 6.9 24.7 4.6 7.3 0.8 4.2 3 1 0 3 3 3 0 Complement Clr-like EGF-like zf-RING_9 PF13901.6 RUS78572.1 - 7.3e-66 222.1 29.1 4.7e-64 216.2 17.2 2.4 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 RUS78572.1 - 1.4e-06 28.1 9.4 1.4e-06 28.1 9.4 4.5 4 1 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RUS78572.1 - 0.0026 17.7 12.6 0.0026 17.7 12.6 3.4 3 1 0 3 3 3 1 Prokaryotic RING finger family 1 VWA PF00092.28 RUS78573.1 - 6.8e-37 127.4 3.4 2.7e-25 89.6 3.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS78573.1 - 4e-18 66.0 0.2 2.8e-12 47.2 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 RUS78573.1 - 2.1e-10 40.8 0.3 0.00067 19.6 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Copine PF07002.16 RUS78573.1 - 0.019 14.4 2.6 0.89 9.0 0.6 2.4 2 0 0 2 2 2 0 Copine CBM_14 PF01607.24 RUS78575.1 - 1.8e-12 47.2 26.5 5.3e-08 32.9 4.3 3.5 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain AA_permease_2 PF13520.6 RUS78576.1 - 2.1e-47 161.9 26.1 2.1e-47 161.9 26.1 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RUS78576.1 - 1.8e-38 132.4 27.5 1.8e-38 132.4 27.5 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RUS78576.1 - 2.5e-22 78.7 7.4 2.5e-22 78.7 7.4 2.8 3 0 0 3 3 3 1 C-terminus of AA_permease Scramblase PF03803.15 RUS78577.1 - 3.1e-32 111.7 0.3 3.8e-32 111.4 0.3 1.0 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.15 RUS78578.1 - 2.1e-34 118.8 0.0 2.3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Scramblase Neur_chan_LBD PF02931.23 RUS78579.1 - 2.9e-08 33.4 0.3 5.8e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain GWT1 PF06423.12 RUS78579.1 - 0.1 12.7 1.7 0.3 11.2 1.7 1.8 1 0 0 1 1 1 0 GWT1 ASC PF00858.24 RUS78580.1 - 1.2e-39 136.5 0.0 1.4e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Citrus_P18 PF05520.11 RUS78580.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein FA_hydroxylase PF04116.13 RUS78581.1 - 1.4e-15 57.8 13.3 1.4e-15 57.8 13.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 RUS78581.1 - 3.3e-09 36.8 1.5 4.2e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain ASC PF00858.24 RUS78582.1 - 2.7e-17 62.9 0.0 2.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Thioredoxin PF00085.20 RUS78583.1 - 2.9e-12 46.5 0.0 5.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 RUS78583.1 - 0.0024 17.7 0.1 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 RUS78583.1 - 0.0099 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RUS78583.1 - 0.042 14.2 0.0 0.18 12.2 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS78583.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Trypan_PARP PF05887.11 RUS78583.1 - 0.19 11.7 1.8 0.22 11.5 0.3 1.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) TTKRSYEDQ PF10212.9 RUS78584.1 - 5.5e-10 38.9 0.0 8.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein RNase_H PF00075.24 RUS78584.1 - 0.00019 21.6 0.0 0.00045 20.4 0.0 1.6 1 1 0 1 1 1 1 RNase H ELO PF01151.18 RUS78585.1 - 1.6e-63 214.6 28.8 1.9e-63 214.3 28.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Aminotran_5 PF00266.19 RUS78586.1 - 1.5e-12 47.1 0.0 2.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SWC7 PF17330.2 RUS78586.1 - 0.022 14.8 0.0 0.14 12.2 0.0 2.2 3 0 0 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 TED_complement PF07678.14 RUS78587.1 - 7.6e-71 238.7 0.0 1.1e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 RUS78587.1 - 3.7e-29 101.9 6.5 4.2e-28 98.4 0.5 4.0 4 1 0 4 4 4 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 RUS78587.1 - 2.8e-28 97.6 5.4 1.2e-27 95.5 1.7 3.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 RUS78587.1 - 1.8e-18 67.0 0.1 6.9e-18 65.1 0.1 2.2 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG2 PF01835.19 RUS78587.1 - 5.7e-16 58.8 0.1 3.4e-15 56.3 0.1 2.5 1 0 0 1 1 1 1 MG2 domain MG3 PF17791.1 RUS78587.1 - 3e-11 43.4 0.0 1.3e-10 41.3 0.0 2.2 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG1 PF17790.1 RUS78587.1 - 0.012 16.0 0.3 0.08 13.4 0.0 2.6 2 0 0 2 2 2 0 Macroglobulin domain MG1 Soyouz_module PF14313.6 RUS78587.1 - 0.096 12.5 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SQHop_cyclase_C PF13243.6 RUS78587.1 - 0.13 11.4 0.0 0.45 9.6 0.0 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain CitMHS PF03600.16 RUS78589.1 - 3.5e-48 164.3 14.9 6.5e-48 163.5 14.9 1.4 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 RUS78589.1 - 2.9e-06 26.6 28.6 0.00089 18.4 6.4 2.8 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region Vac7 PF12751.7 RUS78589.1 - 0.0017 17.9 1.1 0.003 17.1 0.3 1.7 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 ArsB PF02040.15 RUS78589.1 - 0.045 13.1 26.6 0.03 13.7 14.2 2.7 2 1 0 2 2 2 0 Arsenical pump membrane protein DUF4674 PF15719.5 RUS78589.1 - 0.13 12.3 3.4 0.066 13.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) DUF1902 PF08972.11 RUS78591.1 - 0.0012 18.8 0.5 0.15 12.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1902) DUF5054 PF16477.5 RUS78591.1 - 0.0068 16.2 0.2 0.0074 16.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5054) DUF43 PF01861.16 RUS78591.1 - 0.023 13.9 0.3 0.12 11.6 0.2 1.9 1 1 1 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain Phage_HK97_TLTM PF06120.11 RUS78591.1 - 0.026 13.7 0.4 0.03 13.5 0.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein FlgN PF05130.12 RUS78591.1 - 0.027 15.0 2.7 0.039 14.5 2.7 1.3 1 0 0 1 1 1 0 FlgN protein Syntaxin-6_N PF09177.11 RUS78591.1 - 0.1 13.2 1.8 0.2 12.2 1.8 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4976 PF16347.5 RUS78593.1 - 0.023 15.0 0.8 1.8 8.9 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) HALZ PF02183.18 RUS78593.1 - 0.095 12.9 0.5 0.095 12.9 0.5 4.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF812 PF05667.11 RUS78593.1 - 0.24 10.2 29.7 0.12 11.2 8.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF745 PF05335.13 RUS78593.1 - 1.3 8.7 24.9 0.51 10.0 9.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF745) CorA PF01544.18 RUS78593.1 - 2 7.6 22.1 4.7 6.4 0.1 3.0 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Hormone_1 PF00103.20 RUS78593.1 - 2.5 7.8 13.5 2.8 7.6 5.9 2.9 2 1 1 3 3 3 0 Somatotropin hormone family FlaC_arch PF05377.11 RUS78593.1 - 2.5 8.5 18.6 8.9 6.8 0.2 4.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FdhE PF04216.12 RUS78593.1 - 2.8 7.7 11.1 0.071 13.0 1.9 2.5 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation DUF1664 PF07889.12 RUS78593.1 - 2.8 8.0 16.8 8.8 6.4 2.6 4.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4988 PF16378.5 RUS78593.1 - 3.1 7.4 5.9 4.7 6.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function G10 PF01125.17 RUS78593.1 - 7.1 6.4 8.8 2.1 8.1 4.7 2.2 2 1 0 2 2 2 0 G10 protein Ank_2 PF12796.7 RUS78594.1 - 4.6e-21 75.2 0.0 4.5e-13 49.6 0.0 3.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78594.1 - 2.1e-16 60.1 2.9 9.5e-08 32.4 0.0 5.1 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS78594.1 - 2.7e-16 59.4 1.1 4.9e-06 26.7 0.0 5.7 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78594.1 - 5.4e-14 50.9 2.5 0.019 15.4 0.0 7.0 6 1 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RUS78594.1 - 5.9e-14 51.8 3.7 0.0014 18.9 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Frtz PF11768.8 RUS78595.1 - 1.2e-197 657.6 0.0 1.4e-197 657.3 0.0 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz CENP-B_dimeris PF09026.10 RUS78595.1 - 0.3 11.5 4.0 0.65 10.4 4.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_S10 PF00338.22 RUS78596.1 - 1.2e-11 44.7 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Nop53 PF07767.11 RUS78597.1 - 2.2e-66 224.9 39.7 2.8e-66 224.5 39.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Fibrinogen_C PF00147.18 RUS78598.1 - 1.5e-35 123.0 1.1 1.7e-35 122.9 1.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Phage_C PF12025.8 RUS78598.1 - 3.7 7.5 4.9 7 6.6 0.0 2.6 3 0 0 3 3 3 0 Phage protein C zf-C2H2 PF00096.26 RUS78599.1 - 5.7e-18 64.3 23.4 2.3e-05 24.6 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78599.1 - 2.8e-15 56.0 22.5 6.3e-07 29.5 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78599.1 - 6.4e-12 45.2 20.7 0.026 15.3 0.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RUS78599.1 - 0.021 15.0 7.6 3.8 7.6 0.1 3.5 1 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 RUS78599.1 - 0.021 15.1 12.9 0.2 12.0 0.6 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding IBR PF01485.21 RUS78599.1 - 0.026 14.8 1.3 0.026 14.8 1.3 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Raffinose_syn PF05691.12 RUS78599.1 - 0.028 12.2 0.0 0.041 11.7 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 CCAP PF11105.8 RUS78599.1 - 0.058 13.4 3.9 1.1 9.2 0.8 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-TRAF PF02176.18 RUS78599.1 - 0.063 14.0 12.2 6.4 7.5 0.1 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger CHORD PF04968.12 RUS78599.1 - 0.12 13.1 11.2 10 7.0 2.3 3.6 1 1 3 4 4 4 0 CHORD zf-met PF12874.7 RUS78599.1 - 0.12 12.8 7.6 1.3 9.5 0.5 3.0 3 0 0 3 3 2 0 Zinc-finger of C2H2 type Transpos_assoc PF13963.6 RUS78599.1 - 0.26 11.6 3.9 5.8 7.3 0.1 2.8 2 1 1 3 3 3 0 Transposase-associated domain zf-C2H2_11 PF16622.5 RUS78599.1 - 0.59 9.9 6.9 4 7.3 0.4 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 RUS78599.1 - 0.66 10.3 4.2 2.3 8.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon zf-CGNR PF11706.8 RUS78599.1 - 0.82 9.6 6.4 6.2 6.8 0.4 3.2 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_8 PF15909.5 RUS78599.1 - 0.83 10.0 5.3 70 3.8 5.3 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 RUS78599.1 - 0.86 10.3 4.7 21 5.8 1.3 3.0 3 1 0 3 3 2 0 FOXP coiled-coil domain zf_UBZ PF18439.1 RUS78599.1 - 1.1 8.9 3.8 3.4 7.3 0.2 3.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 RUS78599.1 - 4 7.6 5.1 3.4 7.8 0.1 2.9 4 0 0 4 4 3 0 XPA protein N-terminal DUF629 PF04780.12 RUS78599.1 - 4 5.9 5.5 2.7 6.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FA_desaturase PF00487.24 RUS78600.1 - 2e-26 93.4 17.3 2e-26 93.4 17.3 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 RUS78600.1 - 8.2e-21 73.2 0.7 1.5e-20 72.4 0.7 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DEAD PF00270.29 RUS78601.1 - 2.6e-42 144.6 0.4 4.5e-42 143.8 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS78601.1 - 3.8e-32 110.9 0.0 1.9e-31 108.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 RUS78601.1 - 0.00027 21.3 0.1 0.0016 18.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS78601.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RUS78601.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RUS78601.1 - 0.0066 15.3 0.0 2.2 6.9 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 RUS78601.1 - 0.15 12.3 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain GDA1_CD39 PF01150.17 RUS78602.1 - 2.3e-74 250.6 0.0 3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ProQ_C PF17516.2 RUS78604.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain Tubulin PF00091.25 RUS78605.1 - 5.7e-68 229.0 0.0 7.9e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS78605.1 - 6.7e-52 174.9 0.0 1.2e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS78605.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain p450 PF00067.22 RUS78606.1 - 1.6e-102 343.6 0.0 1.9e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EIAV_GP90 PF00971.18 RUS78610.1 - 0.037 12.7 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 COG7 PF10191.9 RUS78612.1 - 1e-186 622.5 19.6 1.3e-186 622.2 19.6 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.9 RUS78612.1 - 3.6e-05 24.0 3.7 3.6e-05 24.0 3.7 3.8 4 0 0 4 4 4 1 Golgi transport complex subunit 5 RdRP_4 PF02123.16 RUS78612.1 - 0.0084 15.0 7.6 0.016 14.1 6.9 1.7 1 1 1 2 2 2 1 Viral RNA-directed RNA-polymerase Snapin_Pallidin PF14712.6 RUS78612.1 - 0.16 12.4 12.8 2.7 8.5 6.9 3.9 3 2 0 3 3 3 0 Snapin/Pallidin Poxvirus_B22R_N PF13169.6 RUS78612.1 - 2 8.9 4.7 2.5 8.6 0.5 3.1 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal DUF2433 PF10360.9 RUS78612.1 - 2.1 8.5 5.0 8.1 6.6 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2433) FlaC_arch PF05377.11 RUS78612.1 - 7.2 7.1 8.8 33 5.0 0.4 4.7 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) zf-C2H2 PF00096.26 RUS78614.1 - 3.2e-24 84.0 40.6 3.9e-06 27.0 1.2 7.2 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS78614.1 - 5.3e-18 64.2 38.6 8e-05 23.2 0.2 6.2 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS78614.1 - 4e-16 58.6 39.6 3.6e-07 30.3 0.1 6.3 6 1 0 6 6 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS78614.1 - 2.3e-11 43.7 6.9 0.22 11.8 0.1 5.0 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS78614.1 - 8e-06 25.5 16.8 0.025 14.3 0.3 5.3 5 0 0 5 5 5 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RUS78614.1 - 0.00011 22.2 17.2 0.19 11.9 3.8 4.2 3 1 1 4 4 4 3 Zinc ribbon domain zf-C2H2_6 PF13912.6 RUS78614.1 - 0.00017 21.5 23.1 0.00049 20.0 1.5 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 RUS78614.1 - 0.00034 20.9 19.3 0.1 12.9 0.6 4.2 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RUS78614.1 - 0.0007 19.1 14.1 3.5 7.3 0.1 5.3 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS78614.1 - 0.0027 18.0 18.6 2.9 8.4 0.3 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RUS78614.1 - 0.029 14.3 0.8 0.029 14.3 0.8 4.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 RUS78614.1 - 0.13 12.2 7.1 3.1 7.8 0.1 4.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 RUS78614.1 - 0.15 12.0 22.7 0.54 10.2 0.5 4.9 2 2 1 3 3 3 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 RUS78614.1 - 0.43 10.4 0.1 0.43 10.4 0.1 6.0 5 1 0 5 5 5 0 C2H2-type zinc-finger domain HypA PF01155.19 RUS78614.1 - 0.66 10.0 16.7 7.1 6.7 1.4 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 RUS78614.1 - 1.3 9.8 19.2 0.26 12.1 0.5 3.4 1 1 0 2 2 2 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 RUS78614.1 - 1.8 9.1 11.5 32 5.1 1.0 4.7 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 RUS78614.1 - 2.2 8.4 26.0 3.3 7.8 0.1 5.5 1 1 4 5 5 5 0 BED zinc finger zinc_ribbon_9 PF14369.6 RUS78614.1 - 2.3 8.5 17.7 3.3 8.0 0.6 4.7 5 0 0 5 5 4 0 zinc-ribbon Zn_ribbon_recom PF13408.6 RUS78614.1 - 2.5 8.7 26.6 1.5 9.4 8.7 4.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-HYPF PF07503.12 RUS78614.1 - 5.8 6.8 17.4 16 5.3 0.3 4.2 3 2 0 3 3 3 0 HypF finger zf-AN1 PF01428.16 RUS78614.1 - 8.2 6.7 22.2 40 4.5 0.1 5.4 5 0 0 5 5 5 0 AN1-like Zinc finger MFS_1 PF07690.16 RUS78615.1 - 3.5e-31 108.4 44.0 3.4e-18 65.7 17.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 RUS78615.1 - 6.8e-05 21.3 0.5 0.00034 19.0 0.0 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family nsp8 PF08717.10 RUS78616.1 - 0.057 13.3 0.3 0.098 12.5 0.3 1.3 1 0 0 1 1 1 0 nsp8 replicase ParcG PF10274.9 RUS78619.1 - 1.5e-47 162.1 0.0 1.9e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Galactosyl_T PF01762.21 RUS78620.1 - 1.5e-33 116.3 0.0 2.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DUF600 PF04634.12 RUS78620.1 - 0.0011 19.0 0.3 0.003 17.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF600 FAP206 PF12018.8 RUS78621.1 - 2.3e-97 325.8 3.9 4.6e-97 324.8 3.9 1.5 1 0 0 1 1 1 1 Domain of unknown function GCP_N_terminal PF17681.1 RUS78621.1 - 0.019 14.6 2.0 1.8 8.1 1.9 3.0 2 1 0 2 2 2 0 Gamma tubulin complex component N-terminal End3 PF12761.7 RUS78621.1 - 0.16 12.2 5.5 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Ipi1_N PF12333.8 RUS78622.1 - 1.4e-10 41.7 0.1 7.7e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF1411 PF07199.11 RUS78622.1 - 0.052 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) DUF2621 PF11084.8 RUS78622.1 - 0.075 13.0 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) MtN3_slv PF03083.16 RUS78623.1 - 8.8e-42 141.0 15.8 8.3e-25 86.7 1.7 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 RUS78623.1 - 0.051 13.3 0.1 0.051 13.3 0.1 4.1 3 2 2 5 5 5 0 PQ loop repeat TMEM43 PF07787.12 RUS78623.1 - 0.24 10.8 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 43 DSL PF01414.19 RUS78625.1 - 2.2e-13 50.2 7.3 2.2e-13 50.2 7.3 2.5 2 0 0 2 2 2 1 Delta serrate ligand EGF_CA PF07645.15 RUS78625.1 - 0.0019 18.4 8.0 0.0019 18.4 8.0 2.5 1 1 1 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 RUS78625.1 - 2.3 8.6 23.3 0.17 12.2 10.5 3.7 4 0 0 4 4 4 0 EGF-like domain DSPc PF00782.20 RUS78626.1 - 1.4e-15 57.3 0.1 1.8e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Organ_specific PF10950.8 RUS78627.1 - 0.14 12.9 2.6 0.29 11.8 2.6 1.5 1 0 0 1 1 1 0 Organ specific protein Glyco_hydro_2_C PF02836.17 RUS78629.1 - 5.4e-83 278.6 0.1 7.1e-83 278.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 RUS78629.1 - 2.2e-23 83.0 0.2 4.2e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 RUS78629.1 - 0.0002 22.0 0.0 0.00037 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 RUS78629.1 - 0.051 14.2 0.2 0.14 12.7 0.2 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Tcp10_C PF07202.13 RUS78630.1 - 1.4e-68 230.3 1.0 6.5e-68 228.1 0.9 2.3 1 1 1 2 2 2 2 T-complex protein 10 C-terminus DUF108 PF01958.18 RUS78631.1 - 4.1e-21 75.1 0.0 6.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 RUS78631.1 - 1.8e-11 44.7 0.0 3.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 RUS78631.1 - 3e-07 30.6 0.0 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 RUS78631.1 - 0.0089 16.3 0.2 0.26 11.7 0.0 2.6 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RUS78631.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 RUS78631.1 - 0.11 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Peptidase_M10 PF00413.24 RUS78632.1 - 5.9e-36 123.7 0.0 1e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 RUS78632.1 - 1.2e-06 28.6 0.0 1.7e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 RUS78632.1 - 0.0005 20.0 0.0 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 1 Hemopexin SelP_N PF04592.14 RUS78632.1 - 0.015 14.7 4.5 0.039 13.3 4.5 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Metallopep PF12044.8 RUS78632.1 - 0.017 13.7 0.1 0.033 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 RUS78632.1 - 0.05 13.7 1.6 0.059 13.5 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12 Astacin PF01400.24 RUS78632.1 - 0.06 13.0 0.1 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) TFIIA PF03153.13 RUS78632.1 - 0.093 12.7 7.0 0.14 12.1 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2946 PF11162.8 RUS78632.1 - 0.17 12.6 1.0 0.5 11.1 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PHB_acc_N PF07879.11 RUS78632.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain SDA1 PF05285.12 RUS78632.1 - 0.44 9.9 9.0 0.83 9.0 9.0 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 RUS78632.1 - 0.68 8.2 10.9 0.82 7.9 9.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 RUS78632.1 - 0.9 7.7 9.7 1.2 7.3 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2147 PF09917.9 RUS78633.1 - 0.12 13.0 0.5 7.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) Acyl-ACP_TE PF01643.17 RUS78634.1 - 6.4e-05 22.4 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS78634.1 - 0.041 14.4 0.2 0.36 11.3 0.3 2.1 2 0 0 2 2 2 0 Thioesterase-like superfamily TBCC PF07986.12 RUS78634.1 - 0.19 11.5 0.0 0.46 10.2 0.0 1.6 2 0 0 2 2 2 0 Tubulin binding cofactor C zf-MYND PF01753.18 RUS78635.1 - 8.7e-05 22.5 3.6 0.00027 20.9 3.6 1.8 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 RUS78635.1 - 0.0062 16.6 1.6 0.0062 16.6 1.6 1.7 2 1 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 SET PF00856.28 RUS78636.1 - 1.6e-15 57.9 0.0 3.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 SET domain Imm5 PF14423.6 RUS78636.1 - 0.12 12.6 2.9 3.1 8.0 0.3 3.0 3 0 0 3 3 3 0 Immunity protein Imm5 Ank_2 PF12796.7 RUS78637.1 - 6.8e-77 254.1 19.4 3.1e-18 66.1 1.3 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 RUS78637.1 - 1.9e-61 202.0 23.3 3.4e-07 30.4 0.1 11.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.6 RUS78637.1 - 1.6e-57 191.2 17.0 6.6e-09 36.1 0.1 9.6 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS78637.1 - 1.7e-51 171.6 16.6 8.3e-11 41.9 0.2 9.5 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS78637.1 - 8.9e-49 157.8 4.3 2.1e-05 24.5 0.1 11.2 11 0 0 11 11 11 10 Ankyrin repeat DUF5535 PF17687.1 RUS78637.1 - 0.056 13.6 0.0 22 5.2 0.0 3.6 3 1 0 4 4 4 0 Family of unknown function (DUF5535) DUF4766 PF15973.5 RUS78637.1 - 0.099 13.2 0.2 0.23 12.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) DUF1521 PF07481.11 RUS78637.1 - 0.61 10.1 5.1 20 5.2 0.1 3.9 2 2 2 4 4 4 0 Domain of Unknown Function (DUF1521) adh_short PF00106.25 RUS78638.1 - 5.7e-20 71.6 0.0 7.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS78638.1 - 2.7e-12 46.7 0.0 4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS78638.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 KR domain FmdE PF02663.14 RUS78638.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Sulfotransfer_1 PF00685.27 RUS78639.1 - 7.2e-23 81.4 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS78639.1 - 7.1e-09 36.4 0.0 2.5e-06 28.0 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS78639.1 - 0.0038 17.2 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family TMEM125 PF15109.6 RUS78639.1 - 1.2 9.5 5.2 2.9 8.3 5.2 1.6 1 0 0 1 1 1 0 TMEM125 protein family Tetraspanin PF00335.20 RUS78640.1 - 3e-05 23.9 0.5 6.3e-05 22.8 0.5 1.7 1 1 0 1 1 1 1 Tetraspanin family DERM PF14704.6 RUS78641.1 - 4.5e-44 150.6 5.1 5.2e-44 150.4 5.1 1.0 1 0 0 1 1 1 1 Dermatopontin DUF963 PF06131.11 RUS78643.1 - 4.5e-11 42.0 30.7 5e-05 22.6 3.1 4.2 1 1 3 4 4 4 4 Schizosaccharomyces pombe repeat of unknown function (DUF963) Tudor-knot PF11717.8 RUS78643.1 - 0.19 11.7 4.2 1.1e+02 2.8 4.2 3.7 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain SpoVIF PF14069.6 RUS78643.1 - 5.2 6.9 20.2 1.3e+02 2.5 9.5 3.2 1 1 1 2 2 2 0 Stage VI sporulation protein F Dpy-30 PF05186.13 RUS78644.1 - 9.7e-08 31.6 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif PAS_4 PF08448.10 RUS78644.1 - 0.015 15.6 0.1 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 PAS fold GHL10 PF02638.15 RUS78644.1 - 0.044 12.9 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 SH3BGR PF04908.15 RUS78645.1 - 2e-25 88.8 0.1 2.3e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 RUS78645.1 - 0.0002 21.5 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 RUS78646.1 - 8e-19 67.6 0.2 9.8e-19 67.4 0.2 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 RUS78646.1 - 7.5e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin zf-CGNR PF11706.8 RUS78647.1 - 0.18 11.7 2.1 0.32 10.9 2.1 1.3 1 0 0 1 1 1 0 CGNR zinc finger VWC PF00093.18 RUS78648.1 - 7.9e-24 83.7 85.5 1.2e-09 38.4 18.6 4.6 4 0 0 4 4 4 4 von Willebrand factor type C domain VWD PF00094.25 RUS78648.1 - 1.1e-05 25.8 1.7 0.026 14.8 0.0 2.8 3 0 0 3 3 3 2 von Willebrand factor type D domain TILa PF12714.7 RUS78648.1 - 0.00015 21.7 11.9 0.00015 21.7 11.9 4.6 4 1 0 4 4 4 3 TILa domain YqcI_YcgG PF08892.11 RUS78649.1 - 0.006 16.5 0.8 0.12 12.2 0.3 2.2 2 0 0 2 2 2 2 YqcI/YcgG family VWC PF00093.18 RUS78650.1 - 4.4e-07 30.1 16.6 4.4e-07 30.1 16.6 1.8 2 0 0 2 2 2 1 von Willebrand factor type C domain CBM_14 PF01607.24 RUS78650.1 - 0.0045 17.1 3.5 0.0045 17.1 3.5 2.5 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain CFC PF09443.10 RUS78650.1 - 0.1 12.4 3.9 0.2 11.5 3.9 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) TILa PF12714.7 RUS78650.1 - 9.2 6.3 21.8 0.31 11.0 14.7 2.2 2 1 0 2 2 2 0 TILa domain TDP43_N PF18694.1 RUS78651.1 - 6.6e-33 112.4 0.0 1.6e-32 111.2 0.0 1.7 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 RUS78651.1 - 6.9e-26 89.9 0.0 5.5e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS78651.1 - 1.7e-05 24.8 0.1 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 RUS78651.1 - 0.00015 21.7 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 RL domain Nup35_RRM_2 PF14605.6 RUS78651.1 - 0.00023 21.1 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 RUS78651.1 - 0.047 13.5 0.0 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) RRM_3 PF08777.11 RUS78651.1 - 0.062 13.4 0.0 9.8 6.3 0.0 2.5 1 1 0 2 2 2 0 RNA binding motif DEC-1_N PF04625.13 RUS78651.1 - 4.8 6.1 4.8 7.4 5.5 4.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SH3_1 PF00018.28 RUS78652.1 - 3e-12 45.9 0.1 8.3e-12 44.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS78652.1 - 3.9e-12 45.8 0.0 9.8e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS78652.1 - 1.1e-10 41.0 0.0 2.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 RUS78652.1 - 0.00048 20.6 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 RUS78652.1 - 0.0043 17.0 0.1 0.013 15.4 0.1 1.7 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 RUS78652.1 - 0.046 14.0 0.5 9.3 6.5 0.4 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 RUS78652.1 - 0.074 12.9 0.2 6.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain RhoGEF PF00621.20 RUS78653.1 - 1.3e-20 74.4 1.7 1.3e-20 74.4 1.7 1.9 2 0 0 2 2 2 1 RhoGEF domain Reeler PF02014.16 RUS78656.1 - 2e-07 31.8 0.0 2.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Reeler domain SpoIIIAH PF12685.7 RUS78656.1 - 0.12 12.1 2.3 0.2 11.4 2.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 RUS78656.1 - 0.23 10.2 2.0 0.28 9.9 2.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 RUS78656.1 - 0.43 8.7 37.4 0.53 8.4 37.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF5523 PF17661.1 RUS78656.1 - 0.83 9.3 3.2 1.1 8.9 3.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SAPS PF04499.15 RUS78656.1 - 0.87 8.3 7.4 0.97 8.1 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 RUS78656.1 - 2.5 6.8 5.1 3.1 6.5 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Afi1 PF07792.12 RUS78656.1 - 4.2 7.9 18.8 6.7 7.2 18.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SDA1 PF05285.12 RUS78656.1 - 5.7 6.3 40.5 7 6.0 40.5 1.0 1 0 0 1 1 1 0 SDA1 HEAT_2 PF13646.6 RUS78657.1 - 0.00093 19.5 1.4 12 6.4 0.0 4.9 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 RUS78657.1 - 0.019 15.2 0.1 1.1e+02 3.5 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat HNF-1_N PF04814.13 RUS78657.1 - 3.5 8.2 6.9 0.26 11.9 0.3 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RVT_1 PF00078.27 RUS78658.1 - 8.1e-15 54.9 0.4 3.5e-07 30.0 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Srg PF02118.21 RUS78660.1 - 2.6e-05 24.0 13.2 3.3e-05 23.7 13.2 1.1 1 0 0 1 1 1 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 RUS78660.1 - 0.00046 19.9 14.4 0.00058 19.6 14.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5083 PF16890.5 RUS78660.1 - 0.065 13.0 3.3 0.1 12.4 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5083) 7tm_1 PF00001.21 RUS78660.1 - 1.3 8.3 14.1 1.9 7.8 14.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) p450 PF00067.22 RUS78661.1 - 3.1e-80 270.2 0.0 2.3e-43 148.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 7TM_GPCR_Srw PF10324.9 RUS78663.1 - 3e-38 131.9 8.9 1.2e-37 130.0 8.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS78663.1 - 6e-19 68.4 0.3 8e-19 68.0 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78663.1 - 0.00029 20.5 10.3 0.00029 20.5 10.3 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TIR_2 PF13676.6 RUS78666.1 - 0.11 13.1 0.0 1.6 9.4 0.0 2.3 2 1 1 3 3 3 0 TIR domain zf-RING_2 PF13639.6 RUS78667.1 - 6.2e-05 23.3 6.3 6.2e-05 23.3 6.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.24 RUS78667.1 - 0.018 15.2 6.9 0.018 15.2 6.9 3.3 3 0 0 3 3 3 0 B-box zinc finger PHD PF00628.29 RUS78667.1 - 0.023 14.6 8.4 0.023 14.6 8.4 2.4 2 0 0 2 2 2 0 PHD-finger ISK_Channel PF02060.15 RUS78667.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF5071 PF16804.5 RUS78667.1 - 0.13 12.5 0.0 1.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) zf-ANAPC11 PF12861.7 RUS78667.1 - 5 7.2 11.8 5.8 7.0 3.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 RUS78667.1 - 5.4 7.4 14.8 8.8 6.7 7.4 2.8 1 1 1 2 2 2 0 RING-like domain GCP_C_terminal PF04130.13 RUS78668.1 - 1.2e-63 215.4 6.4 1.2e-63 215.4 6.4 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RUS78668.1 - 6.8e-34 117.9 0.3 6.8e-34 117.9 0.3 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal LemA PF04011.12 RUS78668.1 - 5.6 6.8 10.7 7.9 6.3 5.7 2.4 1 1 1 2 2 2 0 LemA family PAX PF00292.18 RUS78669.1 - 9.2e-66 219.4 0.2 1.4e-65 218.8 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 RUS78669.1 - 7.8e-07 28.7 0.0 2.9e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 RUS78669.1 - 1.6e-05 25.4 0.0 0.00045 20.8 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 RUS78669.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 RUS78669.1 - 0.0032 17.5 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 RUS78669.1 - 1.2 9.0 2.8 1.6 8.6 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain 7tm_1 PF00001.21 RUS78670.1 - 3.6e-36 124.9 9.8 4.5e-36 124.5 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS78670.1 - 0.00011 21.6 9.6 0.00086 18.7 9.6 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw GST_C PF00043.25 RUS78671.1 - 4.3e-07 30.1 0.3 9e-07 29.0 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS78671.1 - 0.0004 20.5 1.0 0.00081 19.5 0.3 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS78671.1 - 0.0019 18.9 0.0 0.0081 16.9 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 RUS78671.1 - 0.0033 17.7 0.0 0.0048 17.2 0.0 1.5 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 RUS78671.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CEBP1_N PF16368.5 RUS78673.1 - 0.0067 16.0 0.3 0.011 15.3 0.0 1.4 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus Shikimate_DH PF01488.20 RUS78673.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phage_Mu_Gam PF07352.12 RUS78674.1 - 0.016 15.1 6.6 0.045 13.7 3.0 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein FliG_C PF01706.16 RUS78674.1 - 0.017 15.3 6.8 0.043 14.0 1.7 2.2 1 1 1 2 2 2 0 FliG C-terminal domain DUF4132 PF13569.6 RUS78674.1 - 0.045 13.6 3.5 0.062 13.1 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) PMC2NT PF08066.12 RUS78674.1 - 0.061 14.0 2.9 0.15 12.8 1.7 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain SLATT_6 PF18169.1 RUS78674.1 - 0.096 12.3 2.3 0.2 11.3 1.4 1.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Mitofilin PF09731.9 RUS78674.1 - 0.13 11.1 7.4 0.14 11.0 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein eIF-4B PF06273.11 RUS78674.1 - 0.59 9.1 6.7 0.62 9.0 6.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Ovate PF04844.13 RUS78674.1 - 3 7.9 7.0 0.58 10.2 0.9 2.2 2 0 0 2 2 2 0 Transcriptional repressor, ovate TMPIT PF07851.13 RUS78674.1 - 3.1 7.0 7.8 3.9 6.6 7.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein MIG-14_Wnt-bd PF06664.12 RUS78675.1 - 6.9e-88 294.6 26.5 6.9e-88 294.6 26.5 1.6 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion p450 PF00067.22 RUS78676.1 - 1.2e-95 321.0 0.1 1.4e-95 320.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4576 PF15144.6 RUS78677.1 - 0.14 12.0 0.1 6.1 6.8 0.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) Gln-synt_C PF00120.24 RUS78678.1 - 9.9e-63 212.2 0.0 3.7e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.24 RUS78679.1 - 2.6e-43 148.4 0.0 6.8e-42 143.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain TPMT PF05724.11 RUS78681.1 - 9.5e-40 136.6 0.0 1.4e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 RUS78681.1 - 0.018 15.7 0.0 0.08 13.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 RUS78681.1 - 0.046 14.4 0.0 0.32 11.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 RUS78681.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Lipoprotein_15 PF03640.15 RUS78682.1 - 1.5 8.4 5.2 9.2 5.9 3.8 3.0 2 0 0 2 2 2 0 Secreted repeat of unknown function Patched PF02460.18 RUS78683.1 - 1.1e-05 23.8 0.0 1.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Patched family DUF202 PF02656.15 RUS78683.1 - 1.6 9.2 5.5 0.63 10.5 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Cytochrom_B562 PF07361.11 RUS78685.1 - 0.79 10.4 11.9 0.6 10.8 0.4 3.9 2 2 0 3 3 3 0 Cytochrome b562 AAA_27 PF13514.6 RUS78685.1 - 3.4 7.2 10.3 0.99 9.0 2.1 3.1 1 1 1 2 2 2 0 AAA domain DUF1349 PF07081.11 RUS78686.1 - 0.079 12.7 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Carb_anhydrase PF00194.21 RUS78687.1 - 1.3e-52 178.8 0.2 8e-34 117.3 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Nop14 PF04147.12 RUS78689.1 - 2 6.6 42.5 2.2 6.4 42.5 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS78689.1 - 7.9 5.1 13.0 9.1 4.9 13.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein 7tm_1 PF00001.21 RUS78690.1 - 4.9e-06 26.1 3.1 6.4e-06 25.7 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Carb_anhydrase PF00194.21 RUS78691.1 - 5.9e-26 91.5 0.0 7e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3975 PF13126.6 RUS78691.1 - 0.31 11.5 2.9 0.51 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3975) Carb_anhydrase PF00194.21 RUS78692.1 - 5.7e-51 173.5 0.1 6.5e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3995 PF13160.6 RUS78692.1 - 0.066 13.6 0.5 8.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) TPK_B1_binding PF04265.14 RUS78693.1 - 1.3e-06 28.0 0.9 0.24 11.1 0.0 4.9 2 2 2 4 4 4 2 Thiamin pyrophosphokinase, vitamin B1 binding domain DCR PF14047.6 RUS78693.1 - 0.075 13.3 0.8 12 6.2 0.1 3.5 2 1 3 5 5 5 0 Dppa2/4 conserved region DUF3817 PF12823.7 RUS78693.1 - 3.4 8.6 8.0 1.2e+03 0.4 8.0 3.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3817) CarbopepD_reg_2 PF13715.6 RUS78695.1 - 1.5e-10 40.9 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 RUS78695.1 - 7.2e-09 35.8 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 RUS78695.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Peptidase_M14 PF00246.24 RUS78696.1 - 2.3e-149 497.0 0.0 8.6e-77 258.8 0.0 6.1 4 2 1 5 5 5 5 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 RUS78696.1 - 7.8e-27 93.4 3.1 7.2e-13 48.6 0.3 2.4 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 RUS78696.1 - 1.7e-12 47.1 0.1 4.7e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 CarboxypepD_reg-like domain PEGA PF08308.11 RUS78696.1 - 0.0051 16.7 0.0 0.92 9.5 0.0 2.5 2 0 0 2 2 2 1 PEGA domain AstE_AspA PF04952.14 RUS78696.1 - 0.0055 15.8 3.6 0.079 12.0 0.1 3.7 4 0 0 4 4 4 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF1533 PF07550.11 RUS78696.1 - 0.033 14.1 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) DUF2817 PF10994.8 RUS78696.1 - 0.047 13.1 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Peptidase_M99 PF17033.5 RUS78696.1 - 0.087 12.2 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Alpha_adaptin_C PF02296.16 RUS78696.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Asp_Arg_Hydrox PF05118.15 RUS78697.1 - 1.8e-41 141.6 0.3 3.3e-41 140.7 0.1 1.6 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase Perm-CXXC PF15629.6 RUS78697.1 - 3.7 7.9 8.8 3.9 7.8 0.8 2.7 3 0 0 3 3 3 0 Permuted single zf-CXXC unit VPDSG-CTERM PF18205.1 RUS78697.1 - 6 6.8 6.9 12 5.9 6.9 1.4 1 0 0 1 1 1 0 VPDSG-CTERM motif CCDC117 PF15810.5 RUS78698.1 - 8.3e-09 35.9 0.7 1.9e-08 34.7 0.7 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 Abhydrolase_3 PF07859.13 RUS78699.1 - 1.5e-42 145.8 0.0 2e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RUS78699.1 - 2.2e-06 26.8 0.2 3.3e-06 26.3 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS78699.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aromatic_hydrox PF11723.8 RUS78699.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase BTB_2 PF02214.22 RUS78700.1 - 1.6e-18 66.9 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 RUS78700.1 - 0.0013 19.0 0.0 0.0036 17.5 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Rad51 PF08423.11 RUS78701.1 - 7e-38 130.3 0.1 9.4e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 RUS78701.1 - 4e-10 39.5 1.5 2e-09 37.1 1.5 2.1 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 RUS78701.1 - 2.3e-08 33.9 0.0 1.1e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 RUS78701.1 - 6.1e-06 25.8 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 RUS78701.1 - 0.0035 16.9 0.2 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.6 RUS78701.1 - 0.028 14.6 0.1 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RUS78701.1 - 0.037 14.3 1.5 0.18 12.1 1.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS78701.1 - 0.042 13.6 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS78701.1 - 0.15 12.6 0.5 0.39 11.3 0.5 1.9 1 1 0 1 1 1 0 AAA domain DUF2400 PF09674.10 RUS78701.1 - 0.17 11.9 1.1 2.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) AAA PF00004.29 RUS78701.1 - 0.47 10.9 2.3 1.1 9.7 0.7 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF525 PF04379.14 RUS78702.1 - 2.7e-29 101.2 0.2 4.4e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 RUS78702.1 - 6.9e-11 42.5 0.5 2.9e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like NIPSNAP PF07978.13 RUS78703.1 - 5.9e-40 135.6 1.6 2.9e-30 104.5 0.2 2.4 2 0 0 2 2 2 2 NIPSNAP DUF5354 PF17305.2 RUS78703.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5354) BCL_N PF04714.13 RUS78704.1 - 1.4e-25 89.0 7.2 3.4e-25 87.9 7.2 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Transp_inhibit PF18791.1 RUS78705.1 - 0.36 10.4 1.2 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain CLAMP PF14769.6 RUS78706.1 - 2e-38 130.8 4.6 3.5e-38 130.1 4.6 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Lectin_C PF00059.21 RUS78707.1 - 1.5e-112 369.9 52.3 3.3e-21 76.1 0.9 6.4 6 0 0 6 6 6 6 Lectin C-type domain Chordopox_A33R PF05966.12 RUS78707.1 - 9.8e-05 21.7 8.9 1.9 7.7 0.0 5.2 5 0 0 5 5 5 2 Chordopoxvirus A33R protein UL45 PF05473.12 RUS78707.1 - 0.0043 16.7 17.3 7.6 6.1 0.2 6.3 5 1 0 6 6 6 3 UL45 protein, carbohydrate-binding C-type lectin-like EphA2_TM PF14575.6 RUS78707.1 - 0.0067 17.3 0.0 0.051 14.4 0.2 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain PSA_CBD PF18341.1 RUS78707.1 - 0.013 15.5 0.1 11 6.1 0.0 3.7 3 0 0 3 3 3 0 PSA endolysin C-terminal cell wall binding domain CBM_14 PF01607.24 RUS78707.1 - 0.026 14.7 9.5 33 4.7 0.0 5.6 5 0 0 5 5 5 0 Chitin binding Peritrophin-A domain DUF5563 PF17718.1 RUS78707.1 - 0.57 9.7 12.6 48 3.4 0.0 6.0 6 0 0 6 6 6 0 Family of unknown function (DUF5563) AT_hook PF02178.19 RUS78708.1 - 4.4 7.5 8.9 0.12 12.4 2.0 2.1 2 0 0 2 2 2 0 AT hook motif LRR_8 PF13855.6 RUS78709.1 - 4e-50 167.4 62.9 2.1e-13 49.8 1.1 10.3 7 2 4 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 RUS78709.1 - 2.4e-29 100.9 60.0 0.00011 22.5 0.1 11.6 9 1 4 13 13 13 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS78709.1 - 9.6e-15 54.7 3.3 6.4e-07 29.4 0.0 3.6 2 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS78709.1 - 1.8e-09 36.8 58.5 0.17 12.5 0.6 15.0 14 3 0 14 14 14 6 Leucine Rich Repeat LRR_9 PF14580.6 RUS78709.1 - 3.1e-05 23.5 12.6 0.071 12.6 0.1 4.3 3 1 1 4 4 4 3 Leucine-rich repeat TIR_2 PF13676.6 RUS78709.1 - 0.00072 20.1 0.0 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 TIR domain Somatomedin_B PF01033.17 RUS78711.1 - 7e-08 32.7 8.6 1.6e-07 31.6 8.6 1.6 1 0 0 1 1 1 1 Somatomedin B domain PHB_acc_N PF07879.11 RUS78711.1 - 0.16 12.1 0.3 1.4 9.0 0.0 2.6 4 0 0 4 4 4 0 PHB/PHA accumulation regulator DNA-binding domain Nop14 PF04147.12 RUS78711.1 - 2.9 6.0 7.3 4 5.5 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family HD_2 PF12917.7 RUS78713.1 - 0.025 14.4 0.7 0.031 14.0 0.6 1.2 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme TetR_C_22 PF17928.1 RUS78713.1 - 0.062 13.6 0.1 0.09 13.1 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CBM_14 PF01607.24 RUS78714.1 - 0.028 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CGI-121 PF08617.10 RUS78715.1 - 2.3e-32 112.3 0.7 2.7e-32 112.2 0.7 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AraC_N PF06719.13 RUS78715.1 - 0.03 14.0 0.0 0.07 12.8 0.0 1.7 1 1 0 1 1 1 0 AraC-type transcriptional regulator N-terminus UCH PF00443.29 RUS78716.1 - 2.7e-20 72.9 0.0 2.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS78716.1 - 1.7e-07 31.1 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 RUS78717.1 - 3.9e-12 46.2 0.0 4.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS78717.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cadherin PF00028.17 RUS78718.1 - 3.5e-40 136.4 3.5 2e-17 63.4 0.3 3.1 3 0 0 3 3 3 3 Cadherin domain Cadherin_3 PF16184.5 RUS78718.1 - 0.00021 21.2 5.1 0.03 14.3 0.1 3.2 3 0 0 3 3 3 2 Cadherin-like Cadherin_2 PF08266.12 RUS78718.1 - 0.0034 17.2 0.2 0.18 11.6 0.1 2.8 3 0 0 3 3 3 1 Cadherin-like Orf78 PF06024.12 RUS78719.1 - 3.7e-06 27.2 10.0 0.031 14.6 2.3 3.2 1 1 2 3 3 3 2 Orf78 (ac78) SDA1 PF05285.12 RUS78719.1 - 0.0009 18.8 19.1 0.0014 18.2 19.1 1.3 1 0 0 1 1 1 1 SDA1 TctB PF07331.11 RUS78719.1 - 0.0016 18.7 0.0 0.06 13.6 0.0 2.2 1 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Pox_Ag35 PF03286.14 RUS78719.1 - 0.0028 17.5 0.7 0.0028 17.5 0.7 2.3 1 1 1 2 2 1 1 Pox virus Ag35 surface protein DUF898 PF05987.13 RUS78719.1 - 0.028 13.5 7.8 0.18 10.8 8.0 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DHHC PF01529.20 RUS78719.1 - 0.037 14.1 5.8 0.17 12.0 4.4 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase RNase_H2_suC PF08615.11 RUS78719.1 - 0.054 13.7 1.6 5.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2615 PF11027.8 RUS78719.1 - 0.076 13.2 0.6 0.076 13.2 0.6 4.1 1 1 2 3 3 2 0 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 RUS78719.1 - 0.17 12.8 11.8 19 6.2 0.0 4.0 3 2 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SARAF PF06682.12 RUS78719.1 - 0.17 11.5 0.2 4.5 6.8 0.0 2.6 1 1 2 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis CobT PF06213.12 RUS78719.1 - 0.36 10.2 22.7 0.69 9.2 3.3 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RSN1_TM PF13967.6 RUS78719.1 - 0.52 10.1 11.0 0.31 10.8 0.8 2.5 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport MMPL PF03176.15 RUS78719.1 - 0.6 9.0 12.4 0.29 10.0 5.0 2.5 3 0 0 3 3 3 0 MMPL family ABC2_membrane_3 PF12698.7 RUS78719.1 - 0.64 9.1 14.5 0.88 8.6 2.1 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF1676 PF07898.13 RUS78719.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1676) MAM33 PF02330.16 RUS78719.1 - 1.5 8.7 8.7 1.7 8.6 1.9 2.3 2 0 0 2 2 2 0 Mitochondrial glycoprotein DUF4484 PF14831.6 RUS78719.1 - 2.6 8.0 25.3 0.026 14.6 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4484) GRP PF07172.11 RUS78719.1 - 3.4 8.4 7.9 21 5.9 0.0 3.4 3 0 0 3 3 2 0 Glycine rich protein family DUF805 PF05656.14 RUS78719.1 - 3.7 8.0 9.2 36 4.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) zf-U1 PF06220.12 RUS78720.1 - 2.2e-14 52.9 0.2 4e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 RUS78720.1 - 0.0059 16.7 6.0 0.012 15.7 6.0 1.5 1 0 0 1 1 1 1 WW domain Methyltransf_FA PF12248.8 RUS78721.1 - 3.9e-19 68.8 0.3 1.1e-17 64.2 0.1 2.9 3 0 0 3 3 3 1 Farnesoic acid 0-methyl transferase PNP_UDP_1 PF01048.20 RUS78721.1 - 0.0004 19.7 0.1 0.00089 18.6 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily Peptidase_S8 PF00082.22 RUS78723.1 - 2.4e-39 135.4 0.4 2.7e-39 135.2 0.4 1.0 1 0 0 1 1 1 1 Subtilase family DUF1647 PF07801.11 RUS78724.1 - 2.5e-11 43.5 0.8 4e-11 42.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) Mucin2_WxxW PF13330.6 RUS78725.1 - 1.7e-88 291.6 32.1 3.3e-18 66.3 1.5 6.8 6 0 0 6 6 6 6 Mucin-2 protein WxxW repeating region F5_F8_type_C PF00754.25 RUS78725.1 - 4.5e-46 156.1 0.9 1.9e-23 83.0 0.1 2.4 2 0 0 2 2 2 2 F5/8 type C domain TIL PF01826.17 RUS78725.1 - 1.1e-05 25.6 10.9 1.1e-05 25.6 10.9 6.2 5 1 0 5 5 5 1 Trypsin Inhibitor like cysteine rich domain Ldl_recept_a PF00057.18 RUS78725.1 - 1.4e-05 25.2 7.0 1.4e-05 25.2 7.0 5.3 4 0 0 4 4 4 1 Low-density lipoprotein receptor domain class A COG2 PF06148.11 RUS78725.1 - 0.14 12.2 0.0 27 4.9 0.0 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CFC PF09443.10 RUS78725.1 - 2.6 8.0 24.4 0.53 10.2 3.3 5.3 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) VWD PF00094.25 RUS78727.1 - 5.7e-89 296.4 9.6 4.7e-34 117.9 0.9 3.6 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 RUS78727.1 - 3.6e-45 152.2 38.7 4.1e-18 65.6 8.4 8.2 8 1 1 9 9 9 3 C8 domain TIL PF01826.17 RUS78727.1 - 8.2e-25 86.8 67.7 4.2e-11 42.9 16.8 13.3 13 4 0 13 13 13 4 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.13 RUS78727.1 - 1.3e-06 28.0 34.2 2.5e-05 23.9 15.8 9.9 11 0 0 11 11 11 2 Pacifastin inhibitor (LCMII) VWC PF00093.18 RUS78727.1 - 4.2e-06 27.0 28.1 8e-05 22.9 9.4 12.7 8 4 3 11 11 11 3 von Willebrand factor type C domain ANAPC4_WD40 PF12894.7 RUS78728.1 - 1.6e-10 41.1 0.3 0.89 9.9 0.0 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS78728.1 - 1.7e-07 31.8 12.4 0.029 15.2 1.3 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.12 RUS78728.1 - 0.1 12.6 0.4 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 RUS78728.1 - 0.15 10.0 0.6 0.79 7.6 0.1 2.1 2 0 0 2 2 2 0 IKI3 family Nuc_sug_transp PF04142.15 RUS78729.1 - 4.1e-37 128.0 19.0 5.7e-37 127.5 19.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RUS78729.1 - 0.013 15.7 21.6 0.11 12.6 2.3 2.2 2 0 0 2 2 2 0 EamA-like transporter family Peptidase_C2 PF00648.21 RUS78730.1 - 6.8e-83 278.1 0.0 9.4e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS78730.1 - 2.9e-30 105.4 0.0 2.2e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 Calpain large subunit, domain III Ribosomal_L26 PF16906.5 RUS78731.1 - 1.1e-40 137.9 4.1 1.4e-40 137.6 4.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 RUS78731.1 - 1.5e-06 28.0 9.7 2.2e-06 27.4 7.5 2.5 1 1 1 2 2 2 1 KOW motif SspH PF08141.12 RUS78731.1 - 0.002 18.2 0.2 0.0041 17.2 0.2 1.5 1 0 0 1 1 1 1 Small acid-soluble spore protein H family Ints3 PF10189.9 RUS78732.1 - 3.2e-106 353.7 0.6 9.4e-106 352.1 0.6 1.9 1 0 0 1 1 1 1 Integrator complex subunit 3 NifQ PF04891.12 RUS78732.1 - 0.049 14.0 2.7 1.1 9.6 0.0 3.7 4 0 0 4 4 4 0 NifQ PXA PF02194.15 RUS78732.1 - 5.5 6.9 6.7 2 8.4 1.6 2.9 3 1 0 3 3 3 0 PXA domain Branch PF02485.21 RUS78733.1 - 3.4e-27 95.5 0.9 4.9e-27 95.0 0.9 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme IMS PF00817.20 RUS78734.1 - 1.9e-48 164.2 0.1 4.6e-48 163.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RUS78734.1 - 2.5e-16 60.4 0.2 7.7e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain SBP_bac_3 PF00497.20 RUS78735.1 - 4.2e-19 68.9 0.0 1.2e-09 37.9 0.0 3.1 2 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 RUS78735.1 - 5.8e-18 65.2 0.3 9e-18 64.5 0.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS78735.1 - 1.3e-16 60.8 0.1 7.6e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 Ligated ion channel L-glutamate- and glycine-binding site CDC45 PF02724.14 RUS78735.1 - 0.012 13.9 13.8 0.017 13.4 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS78735.1 - 0.098 11.1 15.0 0.14 10.6 15.0 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 RUS78735.1 - 0.34 9.7 0.5 0.54 9.0 0.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4637 PF15470.6 RUS78735.1 - 0.37 10.5 2.5 0.67 9.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) eIF-3c_N PF05470.12 RUS78735.1 - 0.76 8.0 3.7 1.2 7.4 3.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HSP90 PF00183.18 RUS78735.1 - 1.2 8.0 4.9 1.8 7.4 4.9 1.1 1 0 0 1 1 1 0 Hsp90 protein Nop14 PF04147.12 RUS78735.1 - 1.6 6.8 26.8 2.3 6.3 26.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS78735.1 - 2 6.4 42.2 2.8 5.9 42.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Enolase_like_N PF18374.1 RUS78736.1 - 0.011 15.1 0.4 7.8 6.0 0.0 4.4 3 2 1 5 5 5 0 Enolase N-terminal domain-like Lamp PF01299.17 RUS78736.1 - 0.11 12.4 5.7 0.85 9.5 2.6 2.3 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) RP-C_C PF11800.8 RUS78737.1 - 0.03 14.4 0.7 0.046 13.8 0.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MDM10 PF12519.8 RUS78737.1 - 0.1 11.5 0.4 0.14 11.0 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FAM176 PF14851.6 RUS78737.1 - 0.13 12.0 0.8 0.23 11.1 0.8 1.4 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 RUS78737.1 - 0.18 11.2 1.6 0.24 10.8 1.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 RUS78737.1 - 0.46 11.5 5.6 1.2 10.1 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 RUS78737.1 - 3.6 7.5 18.2 5.8 6.8 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2207 PF09972.9 RUS78739.1 - 0.0043 15.9 11.0 0.0046 15.8 11.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TraG_N PF07916.11 RUS78739.1 - 0.7 8.7 6.3 0.88 8.4 6.3 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region MgtE PF01769.16 RUS78739.1 - 2.5 8.5 20.4 3.5 8.0 20.4 1.2 1 0 0 1 1 1 0 Divalent cation transporter Lig_chan-Glu_bd PF10613.9 RUS78740.1 - 1.2e-24 86.7 0.0 2.1e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS78740.1 - 1.2e-13 51.0 0.0 2.1e-12 46.9 0.0 2.4 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 LVIVD PF08309.11 RUS78740.1 - 0.068 12.5 6.9 1.9 7.9 0.2 2.9 3 0 0 3 3 3 0 LVIVD repeat zf-C2H2_4 PF13894.6 RUS78742.1 - 0.0016 19.1 0.9 0.0045 17.7 0.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS78742.1 - 0.025 15.0 0.8 0.065 13.7 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type YL1 PF05764.13 RUS78743.1 - 9.1e-46 156.9 28.2 9.1e-46 156.9 28.2 2.0 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 RUS78743.1 - 1.7e-11 43.7 0.9 1.7e-11 43.7 0.9 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Acetyltransf_CG PF14542.6 RUS78744.1 - 5.8e-19 68.0 0.0 9.6e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase CBFD_NFYB_HMF PF00808.23 RUS78745.1 - 0.058 13.7 0.9 0.14 12.5 0.7 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 7tm_1 PF00001.21 RUS78746.1 - 7.9e-11 41.8 0.0 7.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS78747.1 - 2.2e-28 99.4 2.8 2.7e-28 99.0 2.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS78747.1 - 9.8e-09 35.0 3.7 1.5e-08 34.4 3.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS78747.1 - 0.0015 18.2 7.6 0.003 17.2 7.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS78747.1 - 0.0019 18.0 6.5 0.0025 17.6 6.5 1.2 1 0 0 1 1 1 1 Olfactory receptor MTABC_N PF16185.5 RUS78747.1 - 0.27 10.7 4.8 0.42 10.1 4.8 1.5 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Aminotran_1_2 PF00155.21 RUS78748.1 - 5.5e-37 127.8 0.0 7.4e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS78748.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_18 PF00704.28 RUS78750.1 - 8.3e-75 252.4 0.0 9.7e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TIR_2 PF13676.6 RUS78750.1 - 0.06 13.9 0.0 14 6.3 0.0 2.8 3 0 0 3 3 3 0 TIR domain Hexapep PF00132.24 RUS78751.1 - 0.097 12.4 20.3 0.85 9.4 1.6 4.2 1 1 3 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DUF4640 PF15480.6 RUS78751.1 - 0.28 10.9 3.9 11 5.6 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4640) Nup88 PF10168.9 RUS78754.1 - 0.05 11.4 1.5 0.06 11.2 0.7 1.4 2 0 0 2 2 2 0 Nuclear pore component rve_3 PF13683.6 RUS78755.1 - 0.041 13.7 1.3 0.66 9.8 1.0 2.4 2 0 0 2 2 2 0 Integrase core domain Arm PF00514.23 RUS78756.1 - 8.2e-05 22.5 0.2 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat IATP PF04568.12 RUS78758.1 - 3 8.3 13.6 1.6 9.2 9.4 2.5 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP AAA_6 PF12774.7 RUS78759.1 - 1.1e-160 534.1 0.1 3.3e-158 525.8 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS78759.1 - 5.6e-147 490.0 11.5 5.6e-147 490.0 11.5 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RUS78759.1 - 2.7e-117 391.4 0.0 1.2e-116 389.2 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RUS78759.1 - 1.5e-103 345.6 3.8 3e-103 344.7 0.0 3.1 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RUS78759.1 - 1.8e-92 308.4 1.6 3.7e-90 300.9 0.2 3.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RUS78759.1 - 3.4e-80 267.8 0.1 2.4e-76 255.3 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RUS78759.1 - 3.1e-54 183.2 0.7 9.4e-54 181.6 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 RUS78759.1 - 7e-50 170.0 5.0 1.2e-49 169.2 5.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS78759.1 - 3.5e-45 152.9 1.0 4.5e-44 149.4 0.0 3.5 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RUS78759.1 - 4.4e-34 117.4 1.7 1.7e-33 115.5 0.8 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RUS78759.1 - 1.8e-22 79.4 0.2 1.1e-21 76.9 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RUS78759.1 - 4.8e-15 55.8 0.0 0.0023 17.9 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS78759.1 - 6.3e-06 26.7 0.1 0.56 10.6 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS78759.1 - 1.5e-05 25.2 1.0 0.35 11.1 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 RUS78759.1 - 0.00013 22.6 0.1 0.054 14.0 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 RUS78759.1 - 0.0003 21.2 1.6 0.93 9.9 0.0 5.3 6 0 0 6 6 5 1 AAA ATPase domain T2SSE PF00437.20 RUS78759.1 - 0.0005 19.2 0.9 0.2 10.7 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 RUS78759.1 - 0.0058 16.4 0.2 1.9 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 RUS78759.1 - 0.01 15.3 0.5 0.18 11.2 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 RUS78759.1 - 0.022 14.1 0.0 3.5 7.0 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 RUS78759.1 - 0.029 14.1 0.1 6.3 6.5 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 RUS78759.1 - 0.036 14.4 0.4 3.6 7.9 0.0 3.5 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 RUS78759.1 - 0.066 11.8 0.4 24 3.4 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Rad17 PF03215.15 RUS78759.1 - 0.088 12.7 0.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain ResIII PF04851.15 RUS78759.1 - 0.11 12.5 3.1 0.9 9.5 0.0 3.6 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 RUS78759.1 - 0.13 12.4 0.1 1.1e+02 3.0 0.1 3.8 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 RUS78759.1 - 0.72 9.3 6.0 8.4 5.8 0.0 3.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Rx_N PF18052.1 RUS78759.1 - 0.92 9.8 4.0 6.4 7.1 0.4 4.4 4 0 0 4 4 2 0 Rx N-terminal domain GAS PF13851.6 RUS78759.1 - 5.1 6.4 14.7 2.9 7.2 2.2 3.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cyt-b5 PF00173.28 RUS78760.1 - 7.9e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 RUS78760.1 - 2.2e-13 50.8 0.0 4.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RUS78760.1 - 1.5e-09 38.1 0.0 9.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain CS PF04969.16 RUS78760.1 - 0.00039 21.4 2.5 0.00093 20.2 2.5 1.7 1 0 0 1 1 1 1 CS domain NAD_binding_6 PF08030.12 RUS78760.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Ferric reductase NAD binding domain IgGFc_binding PF17517.2 RUS78760.1 - 0.057 12.7 0.3 0.12 11.7 0.3 1.5 1 0 0 1 1 1 0 IgGFc binding protein DP PF08781.10 RUS78760.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor DP RVT_1 PF00078.27 RUS78761.1 - 7e-23 81.3 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS78761.1 - 6.9e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS78761.1 - 0.0033 18.0 0.0 0.0076 16.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 RUS78761.1 - 0.0085 16.4 0.0 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease 7TM_GPCR_Srw PF10324.9 RUS78762.1 - 0.00079 18.8 2.6 0.00079 18.8 2.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw PPP4R2 PF09184.11 RUS78762.1 - 0.006 16.2 24.5 0.008 15.8 24.5 1.2 1 0 0 1 1 1 1 PPP4R2 7tm_1 PF00001.21 RUS78762.1 - 0.007 15.7 3.6 0.007 15.7 3.6 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Nop14 PF04147.12 RUS78762.1 - 0.01 14.1 30.7 0.012 13.9 30.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS78762.1 - 0.087 12.1 30.0 0.11 11.8 30.0 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 RUS78762.1 - 0.13 11.2 8.6 0.21 10.5 8.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mpp10 PF04006.12 RUS78762.1 - 1 7.7 35.2 1.3 7.4 35.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS78762.1 - 1.6 8.1 35.8 2 7.7 35.8 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 RUS78762.1 - 1.6 7.6 38.2 2.1 7.3 38.2 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 RUS78762.1 - 3.2 7.5 27.9 4.5 7.0 27.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 RUS78762.1 - 3.8 6.8 35.6 5.3 6.4 35.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4820 PF16091.5 RUS78762.1 - 4.1 6.7 15.0 6.7 6.0 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 RUS78762.1 - 4.6 7.3 8.8 6.5 6.8 8.8 1.3 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.11 RUS78762.1 - 7 6.7 34.7 10 6.1 34.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MCM_bind PF09739.9 RUS78762.1 - 8.4 4.7 12.6 10 4.4 12.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor UPF0560 PF10577.9 RUS78762.1 - 9.2 4.6 9.5 12 4.3 9.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Sushi PF00084.20 RUS78763.1 - 0.0002 21.9 0.7 0.22 12.1 0.0 3.7 2 1 0 2 2 2 2 Sushi repeat (SCR repeat) CUB PF00431.20 RUS78763.1 - 0.0038 17.5 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 RUS78764.1 - 7.9e-07 29.4 0.0 2.9e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 CUB domain SKG6 PF08693.10 RUS78764.1 - 4.4e-05 22.8 2.6 9.1e-05 21.8 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain 7TM_GPCR_Srw PF10324.9 RUS78765.1 - 1.5e-19 70.4 20.3 2.6e-18 66.4 20.3 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS78765.1 - 5.3e-15 55.4 14.1 1.1e-14 54.4 14.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Halogen_Hydrol PF10112.9 RUS78765.1 - 0.062 13.3 0.2 0.062 13.3 0.2 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CCSMST1 PF15013.6 RUS78765.1 - 1.3 9.2 3.5 3.2 8.0 0.1 2.7 2 1 1 3 3 3 0 CCSMST1 family SEA PF01390.20 RUS78769.1 - 7.7e-07 29.2 0.2 1e-06 28.8 0.2 1.2 1 0 0 1 1 1 1 SEA domain DUF4573 PF15140.6 RUS78770.1 - 5.8e-21 75.1 114.2 1e-05 25.4 13.9 8.1 4 2 5 9 9 9 8 Domain of unknown function (DUF4573) SEA PF01390.20 RUS78770.1 - 3.6e-18 65.6 8.4 1.5e-05 25.0 0.2 3.8 3 0 0 3 3 3 3 SEA domain CTD PF12815.7 RUS78770.1 - 0.00032 21.2 4.5 0.49 11.0 2.1 3.2 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 T3SS_needle_F PF09392.10 RUS78770.1 - 0.16 12.2 7.6 10 6.4 0.2 3.8 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Microcephalin PF12258.8 RUS78771.1 - 6.6 5.9 7.8 1.5 8.0 1.9 2.1 1 1 1 2 2 2 0 Microcephalin protein LRR_4 PF12799.7 RUS78772.1 - 5.8e-10 39.3 11.6 0.011 16.1 3.2 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS78772.1 - 5.5e-09 35.7 11.7 0.0015 18.2 0.4 4.9 3 3 0 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 RUS78772.1 - 7e-06 25.7 10.5 3.1 8.1 0.7 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 RUS78772.1 - 0.021 15.3 10.4 1.1e+02 4.0 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat rve_3 PF13683.6 RUS78772.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain LRR_9 PF14580.6 RUS78772.1 - 0.18 11.3 2.6 1.4 8.4 0.9 2.6 2 1 0 2 2 2 0 Leucine-rich repeat C2 PF00168.30 RUS78773.1 - 1.8e-27 95.6 0.1 3e-12 46.7 0.0 2.8 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 RUS78773.1 - 1.2e-20 74.1 0.0 6.7e-12 45.5 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 RUS78773.1 - 3.5e-13 50.0 2.9 5.2e-13 49.4 0.6 2.6 2 0 0 2 2 2 1 PH domain BTK PF00779.19 RUS78773.1 - 2.4e-12 46.4 2.8 6.2e-12 45.1 2.8 1.7 1 0 0 1 1 1 1 BTK motif PH_8 PF15409.6 RUS78773.1 - 0.014 15.6 0.3 0.03 14.6 0.3 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain VWA PF00092.28 RUS78774.1 - 4.4e-41 141.0 0.4 6.1e-41 140.6 0.4 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS78774.1 - 8.8e-12 45.6 0.0 2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 RUS78774.1 - 2.2e-11 43.8 9.0 6.3e-11 42.3 9.0 1.8 1 0 0 1 1 1 1 Thrombospondin type 1 domain VWA_3 PF13768.6 RUS78774.1 - 1.5e-06 28.2 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.15 RUS78775.1 - 6.5e-40 135.1 61.5 2.7e-11 43.5 8.4 4.8 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 RUS78775.1 - 3.4e-21 75.0 35.3 5.2e-07 29.6 4.0 4.6 4 0 0 4 4 4 4 MSP1 EGF domain 1 cEGF PF12662.7 RUS78775.1 - 5.3e-19 67.8 31.4 5e-06 26.3 0.7 5.2 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS78775.1 - 1.1e-12 47.8 51.3 0.001 19.2 8.3 6.3 2 1 3 6 6 6 4 EGF domain FXa_inhibition PF14670.6 RUS78775.1 - 7.3e-10 39.0 52.7 0.014 15.7 8.3 6.0 1 1 4 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS78775.1 - 6.6e-09 35.9 53.2 0.0016 18.7 6.4 5.3 5 1 1 6 6 6 4 EGF-like domain hEGF PF12661.7 RUS78775.1 - 0.00043 20.8 67.7 0.0015 19.1 7.1 6.9 7 0 0 7 7 7 4 Human growth factor-like EGF EGF_2 PF07974.13 RUS78775.1 - 0.028 14.8 6.5 0.028 14.8 6.5 6.0 3 3 3 6 6 6 0 EGF-like domain PPP4R2 PF09184.11 RUS78776.1 - 0.017 14.8 4.3 0.023 14.3 4.3 1.4 1 0 0 1 1 1 0 PPP4R2 RAMP PF04901.13 RUS78776.1 - 0.095 12.7 2.6 0.47 10.5 0.3 2.3 2 0 0 2 2 2 0 Receptor activity modifying family 7TM_GPCR_Srw PF10324.9 RUS78777.1 - 2.5e-10 40.1 14.6 7.2e-07 28.8 1.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS78777.1 - 3.4e-07 29.8 6.0 4.5e-07 29.5 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78777.1 - 0.29 10.7 14.8 0.018 14.7 8.0 2.3 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CARD PF00619.21 RUS78778.1 - 5.5e-06 26.3 0.0 7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 RUS78778.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Caspase recruitment domain Copine PF07002.16 RUS78779.1 - 7.9e-49 166.0 0.0 1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS78779.1 - 4.6e-14 52.6 0.0 8.9e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 RUS78779.1 - 0.003 17.7 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus CHGN PF05679.16 RUS78780.1 - 1.5e-50 172.5 0.2 3.9e-50 171.1 0.2 1.6 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 RUS78780.1 - 3.1e-15 56.3 0.0 4.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS78780.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Galactosyltransferase EGF_2 PF07974.13 RUS78783.1 - 1.2e-06 28.8 15.8 3e-06 27.5 12.6 2.8 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 RUS78783.1 - 0.0004 20.3 4.6 0.0004 20.3 4.6 2.5 2 0 0 2 2 2 1 Tenascin EGF domain hEGF PF12661.7 RUS78783.1 - 0.004 17.7 8.5 0.004 17.7 8.5 3.8 3 0 0 3 3 3 1 Human growth factor-like EGF EGF PF00008.27 RUS78783.1 - 0.012 15.9 12.5 0.26 11.7 9.1 2.9 2 0 0 2 2 2 0 EGF-like domain I-EGF_1 PF18372.1 RUS78783.1 - 0.049 13.7 12.6 0.054 13.6 6.3 3.5 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 DSL PF01414.19 RUS78783.1 - 0.75 10.1 9.5 3.7 7.9 8.8 2.5 2 0 0 2 2 2 0 Delta serrate ligand Laminin_EGF PF00053.24 RUS78783.1 - 6.3 7.0 15.0 0.41 10.8 7.7 2.7 3 0 0 3 3 3 0 Laminin EGF domain Sulfatase PF00884.23 RUS78784.1 - 9.6e-47 159.9 0.0 2.1e-46 158.7 0.0 1.6 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 RUS78784.1 - 9.1e-14 51.6 1.1 4.8e-09 36.4 0.5 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 RUS78784.1 - 0.00014 21.5 0.2 0.27 10.8 0.0 2.6 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 RUS78784.1 - 0.0017 17.5 0.1 0.0031 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Methyltransf_11 PF08241.12 RUS78784.1 - 0.21 12.3 0.0 0.45 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NOA36 PF06524.12 RUS78785.1 - 0.015 14.6 20.8 0.015 14.6 20.8 2.1 2 0 0 2 2 2 0 NOA36 protein MAM33 PF02330.16 RUS78785.1 - 2.8 7.8 13.9 2.6 7.9 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein DUF2457 PF10446.9 RUS78785.1 - 3.9 6.5 77.1 0.21 10.7 27.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS78785.1 - 4.5 5.4 42.1 0.79 7.9 12.7 2.0 2 0 0 2 2 2 0 Nop14-like family E2F_TDP PF02319.20 RUS78786.1 - 1.6e-37 127.3 0.1 1.3e-19 70.0 0.0 2.8 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 RUS78786.1 - 7.9e-05 22.5 0.9 0.0055 16.6 0.1 3.3 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.11 RUS78786.1 - 0.022 14.7 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain B-block_TFIIIC PF04182.12 RUS78786.1 - 0.046 13.9 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC PAE PF03283.13 RUS78787.1 - 4.6e-77 259.5 0.0 6.1e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Ala_racemase_C PF00842.21 RUS78787.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Herpes_BBRF1 PF04793.12 RUS78788.1 - 0.02 13.9 0.2 0.33 10.0 0.2 2.0 1 1 0 1 1 1 0 BRRF1-like protein HrpB1_HrpK PF09613.10 RUS78788.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) UBA_4 PF14555.6 RUS78789.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain HOIP-UBA PF16678.5 RUS78789.1 - 0.048 13.7 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair E1_DerP2_DerF2 PF02221.15 RUS78790.1 - 4.6e-17 62.7 0.7 5.8e-17 62.4 0.7 1.1 1 0 0 1 1 1 1 ML domain Paramyxo_P_V_N PF13825.6 RUS78791.1 - 0.073 12.5 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Stress-antifung PF01657.17 RUS78792.1 - 0.058 14.0 0.6 0.21 12.3 0.0 2.1 2 0 0 2 2 2 0 Salt stress response/antifungal RAD51_interact PF15696.5 RUS78794.1 - 1.4e-05 25.0 3.2 4.6e-05 23.4 3.2 2.0 1 0 0 1 1 1 1 RAD51 interacting motif DUF1394 PF07159.12 RUS78795.1 - 7.8e-137 455.5 6.8 8.9e-137 455.3 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) SDA1 PF05285.12 RUS78798.1 - 0.019 14.4 50.2 0.025 14.0 50.2 1.3 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS78798.1 - 0.026 13.0 51.3 0.03 12.8 51.3 1.2 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS78798.1 - 0.029 13.7 40.6 0.035 13.5 40.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS78798.1 - 0.033 12.4 53.2 0.039 12.2 53.2 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 RUS78798.1 - 0.061 12.8 0.1 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) CDC27 PF09507.10 RUS78798.1 - 0.58 9.5 35.5 0.68 9.3 35.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GAGA_bind PF06217.12 RUS78798.1 - 0.6 10.3 10.4 0.64 10.3 10.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 RUS78798.1 - 1.3 8.8 38.0 2.2 8.0 38.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 RUS78798.1 - 2 8.4 10.4 2.8 7.9 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exo_endo_phos_2 PF14529.6 RUS78799.1 - 0.00069 19.5 0.3 0.0019 18.1 0.3 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Ras PF00071.22 RUS78800.1 - 1.1e-24 86.8 0.0 1.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS78800.1 - 1.9e-12 47.4 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS78800.1 - 0.027 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 RUS78800.1 - 0.078 12.4 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family LCM PF04072.14 RUS78801.1 - 1.4e-27 96.8 0.0 2.7e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 RUS78801.1 - 6.7e-18 64.4 2.6 1.4e-06 28.2 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS78801.1 - 9e-13 47.9 0.0 3.6e-05 23.6 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 RUS78801.1 - 5e-11 42.5 1.3 0.00076 19.7 0.0 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.6 RUS78801.1 - 2.3e-10 40.5 3.1 0.0061 16.8 0.0 4.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS78801.1 - 1.2e-07 31.2 0.1 0.0034 16.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 RUS78801.1 - 1.4e-05 24.9 2.4 0.67 10.0 0.1 4.7 4 0 0 4 4 4 1 Kelch motif RINGv PF12906.7 RUS78801.1 - 0.056 13.6 1.3 0.17 12.1 1.3 1.8 1 0 0 1 1 1 0 RING-variant domain 7tm_1 PF00001.21 RUS78802.1 - 2.5e-24 86.0 5.5 3.2e-24 85.7 5.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PikAIV_N PF18605.1 RUS78802.1 - 0.052 13.1 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Arylesterase PF01731.20 RUS78803.1 - 2.5e-16 59.6 0.0 5.7e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 RUS78803.1 - 1.6e-07 31.2 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RUS78803.1 - 0.0079 16.2 0.0 3.1 8.0 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Lactonase PF10282.9 RUS78803.1 - 0.0091 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RIFIN PF02009.16 RUS78804.1 - 0.028 14.3 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Rifin FixQ PF05545.11 RUS78804.1 - 0.084 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF1129 PF06570.11 RUS78804.1 - 0.17 11.3 0.3 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Carboxyl_trans PF01039.22 RUS78805.1 - 2.5e-194 646.5 0.1 2.9e-194 646.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 RUS78805.1 - 0.048 13.2 0.1 0.34 10.4 0.0 2.2 2 1 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DKCLD PF08068.12 RUS78806.1 - 6.8e-28 96.5 0.0 2.4e-27 94.8 0.1 1.9 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 RUS78806.1 - 3.2e-22 79.5 0.1 6.5e-19 68.8 0.1 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 RUS78806.1 - 5.9e-21 74.4 0.2 1.2e-20 73.4 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 RUS78806.1 - 1.5e-19 69.7 1.3 3.7e-19 68.5 1.3 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 RUS78806.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DUF1682 PF07946.14 RUS78806.1 - 1.2 8.3 10.1 1.9 7.6 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ARGLU PF15346.6 RUS78807.1 - 1.6e-50 170.9 64.2 1.6e-50 170.9 64.2 2.7 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 JAB PF01398.21 RUS78808.1 - 1.6e-37 128.0 0.1 3.4e-37 127.0 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 RUS78808.1 - 2.9e-28 97.8 0.4 9e-28 96.3 0.7 1.7 2 0 0 2 2 2 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 RUS78808.1 - 1.2e-08 34.7 0.1 1.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Sas6_CC PF18594.1 RUS78808.1 - 0.019 14.7 0.5 0.049 13.4 0.5 1.8 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain UPF0172 PF03665.13 RUS78808.1 - 0.08 13.0 0.0 0.29 11.1 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF2757 PF10955.8 RUS78808.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) PhoLip_ATPase_C PF16212.5 RUS78809.1 - 5.2e-65 219.7 27.1 5.2e-65 219.7 27.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RUS78809.1 - 1.5e-21 75.9 0.5 3.9e-21 74.5 0.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RUS78809.1 - 6.8e-09 35.7 0.0 2.1e-07 30.9 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RUS78809.1 - 2.4e-05 23.9 0.0 2.4e-05 23.9 0.0 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RUS78809.1 - 3.8e-05 24.1 0.5 0.16 12.2 0.1 3.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RUS78809.1 - 0.01 15.6 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Barttin PF15462.6 RUS78809.1 - 2.1 8.1 6.8 5.7 6.6 6.8 1.8 1 1 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Hexapep PF00132.24 RUS78811.1 - 1.8e-09 36.9 16.5 0.00022 20.8 1.7 4.4 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 RUS78811.1 - 0.033 13.1 1.6 1.2 7.9 0.2 2.0 1 1 1 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 RUS78811.1 - 9.1 6.1 13.9 1.1 9.0 0.3 3.5 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase RPW8 PF05659.11 RUS78812.1 - 0.28 10.9 11.7 1.2 8.9 9.4 2.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.10 RUS78812.1 - 0.52 10.5 17.3 0.37 11.0 12.3 3.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 RUS78812.1 - 0.61 9.6 16.5 2.9 7.4 16.5 2.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 RUS78812.1 - 5.1 7.6 25.7 1.3e+02 3.1 23.7 3.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Cluap1 PF10234.9 RUS78812.1 - 5.8 6.2 23.7 0.91 8.9 18.4 2.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 UPF0449 PF15136.6 RUS78812.1 - 10 6.7 12.4 4.2e+03 -1.7 12.4 3.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Ceramidase PF05875.12 RUS78813.1 - 1.7e-73 247.3 20.5 1.6e-53 181.9 13.5 2.0 1 1 1 2 2 2 2 Ceramidase Acetyltransf_1 PF00583.25 RUS78814.1 - 8.5e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS78814.1 - 5.2e-09 36.4 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS78814.1 - 7.5e-09 35.6 0.0 1e-08 35.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS78814.1 - 0.0041 17.0 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RUS78814.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 RUS78815.1 - 1.3e-45 155.9 0.0 1.6e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FGGY_N PF00370.21 RUS78816.1 - 8.7e-42 143.4 0.0 1.1e-40 139.7 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RUS78816.1 - 5.6e-38 130.7 0.1 8.6e-38 130.0 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3161 PF11362.8 RUS78816.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) CNH PF00780.22 RUS78817.1 - 1.3e-59 202.1 0.0 2e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 RUS78817.1 - 2.9e-36 125.2 0.0 4.5e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78817.1 - 1.4e-24 86.8 0.0 2.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS78817.1 - 0.00017 20.5 1.0 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS78817.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Voldacs PF03517.13 RUS78817.1 - 3.3 7.8 12.3 3.9 7.6 0.8 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF4632 PF15451.6 RUS78817.1 - 5 7.3 7.1 5.6 7.1 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) SSrecog PF03531.14 RUS78818.1 - 1e-27 95.8 0.3 3.8e-27 94.0 0.3 2.1 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 RUS78818.1 - 1.1e-25 89.9 1.5 1.6e-21 76.5 0.2 3.2 3 0 0 3 3 3 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 RUS78818.1 - 6.3e-25 87.4 0.1 3e-23 82.0 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.19 RUS78818.1 - 3.3e-20 72.2 3.4 3.3e-20 72.2 3.4 2.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS78818.1 - 1.2e-12 48.2 4.2 1.2e-12 48.2 4.2 2.9 2 0 0 2 2 2 1 HMG-box domain Rad51 PF08423.11 RUS78819.1 - 2e-18 66.6 0.2 2.3e-17 63.1 0.2 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 RUS78819.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 RUS78819.1 - 0.027 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PSY3 PF16836.5 RUS78819.1 - 0.029 13.9 0.7 0.043 13.3 0.7 1.2 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description PAXNEB PF05625.11 RUS78819.1 - 0.15 11.1 2.9 1.1 8.4 0.4 2.1 2 0 0 2 2 2 0 PAXNEB protein zf-H2C2_2 PF13465.6 RUS78820.1 - 1.8e-11 43.9 39.4 1.3e-07 31.7 0.2 7.9 8 0 0 8 8 8 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS78820.1 - 9.4e-06 25.3 16.4 0.12 12.1 0.0 5.1 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS78820.1 - 1.8e-05 25.1 48.0 0.13 13.2 2.4 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 RUS78820.1 - 0.018 15.4 26.7 0.39 11.2 1.0 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RUS78820.1 - 0.024 15.1 3.1 0.024 15.1 3.1 3.8 4 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 RUS78820.1 - 0.05 13.4 12.0 0.067 13.0 0.3 3.6 3 1 1 4 4 4 0 GAGA factor zf-C2H2 PF00096.26 RUS78820.1 - 0.2 12.2 0.2 0.2 12.2 0.2 7.0 6 2 1 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 RUS78820.1 - 1.7 8.5 16.9 1.3 9.0 0.3 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_7 PF15269.6 RUS78820.1 - 7.3 6.8 19.9 9.7 6.4 0.6 3.6 3 1 0 3 3 3 0 Zinc-finger RPE65 PF03055.15 RUS78821.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Trypan_PARP PF05887.11 RUS78821.1 - 0.077 13.0 51.4 1 9.3 36.6 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) RPE65 PF03055.15 RUS78822.1 - 9e-46 157.0 0.0 9.9e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Somatomedin_B PF01033.17 RUS78823.1 - 0.00028 21.2 12.5 0.00028 21.2 12.5 3.1 3 0 0 3 3 3 1 Somatomedin B domain Gamma-thionin PF00304.20 RUS78823.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.3 3 0 0 3 3 3 0 Gamma-thionin family TetR_C_1 PF02909.17 RUS78823.1 - 0.22 11.3 1.0 27 4.6 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain 7tm_1 PF00001.21 RUS78824.1 - 4e-18 65.7 0.3 6.4e-18 65.0 0.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS78824.1 - 0.00019 20.9 5.0 0.00019 20.9 5.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS78824.1 - 0.0025 17.2 6.4 0.078 12.2 0.6 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF4603 PF15376.6 RUS78824.1 - 0.18 9.2 2.7 0.26 8.6 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) TPR_12 PF13424.6 RUS78825.1 - 8.8e-31 106.0 14.1 3.6e-13 49.6 1.2 7.3 5 3 1 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 RUS78825.1 - 1.3e-20 72.6 4.0 9.9e-09 34.8 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS78825.1 - 6.2e-08 32.1 5.3 0.00092 19.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS78825.1 - 9.9e-06 25.2 12.3 0.00024 20.8 0.1 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS78825.1 - 0.00017 21.5 10.7 0.14 12.5 0.1 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS78825.1 - 0.0087 16.1 11.0 8.8 6.7 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS78825.1 - 0.013 14.9 2.3 0.45 9.8 0.3 3.5 3 1 1 4 4 4 0 MalT-like TPR region DUF1925 PF09094.11 RUS78825.1 - 0.11 12.9 0.5 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) TPR_14 PF13428.6 RUS78825.1 - 0.22 12.4 2.7 48 5.2 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat C2 PF00168.30 RUS78827.1 - 6.1e-49 164.6 0.1 3.8e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 RUS78827.1 - 1.9e-20 73.2 5.0 3.2e-20 72.5 5.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 RUS78827.1 - 0.00042 20.4 7.1 0.00082 19.5 7.1 1.5 1 0 0 1 1 1 1 Piccolo Zn-finger FYVE PF01363.21 RUS78827.1 - 0.0018 18.4 2.0 0.0045 17.1 2.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger UPF0167 PF03691.14 RUS78827.1 - 0.029 14.2 2.5 0.057 13.2 2.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) DOCK-C2 PF14429.6 RUS78827.1 - 0.099 12.4 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Ribosomal_L37ae PF01780.19 RUS78827.1 - 0.19 11.9 2.0 0.46 10.6 2.0 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family PHD PF00628.29 RUS78827.1 - 0.2 11.6 7.4 0.38 10.7 7.4 1.5 1 0 0 1 1 1 0 PHD-finger Cript PF10235.9 RUS78827.1 - 0.52 10.9 3.9 1.6 9.3 3.9 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-RING_2 PF13639.6 RUS78827.1 - 4.4 7.7 6.8 7.7 6.9 6.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-B_box PF00643.24 RUS78827.1 - 4.9 7.4 8.0 2 8.7 4.4 2.2 2 0 0 2 2 2 0 B-box zinc finger NO_synthase PF02898.15 RUS78829.1 - 3.6e-93 312.5 0.1 1.3e-92 310.6 0.1 1.9 1 1 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 RUS78829.1 - 1.2e-62 211.4 0.0 3e-62 210.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 RUS78829.1 - 7.6e-42 142.9 0.0 2.7e-41 141.1 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 RUS78829.1 - 6.9e-18 65.3 0.0 2.8e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RUS78829.1 - 0.054 13.6 0.0 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferric reductase NAD binding domain SR-25 PF10500.9 RUS78829.1 - 1.7 8.2 13.4 3.1 7.3 13.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PDZ PF00595.24 RUS78831.1 - 1.2e-11 44.8 0.1 3.3e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS78831.1 - 5.4e-08 32.6 2.0 6.3e-08 32.4 0.4 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS78831.1 - 1.5e-05 25.2 0.1 3.7e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain WD40 PF00400.32 RUS78832.1 - 2.2e-16 59.9 1.5 0.0029 18.4 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS78832.1 - 2.7e-10 40.4 0.0 0.044 14.1 0.0 4.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RUS78832.1 - 5.2e-06 26.8 0.0 1.6 9.3 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain Nup160 PF11715.8 RUS78832.1 - 0.00016 20.4 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ PF01011.21 RUS78832.1 - 0.00026 20.7 0.0 0.05 13.6 0.0 3.6 4 0 0 4 4 4 1 PQQ enzyme repeat WD40_like PF17005.5 RUS78832.1 - 0.00043 19.7 1.1 0.0038 16.6 0.6 2.1 1 1 1 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 RUS78832.1 - 0.00048 19.8 0.0 0.066 12.8 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 RUS78832.1 - 0.00075 18.5 0.1 0.022 13.7 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 RUS78832.1 - 0.0019 17.0 0.2 0.43 9.3 0.0 2.4 2 1 1 3 3 3 2 Nup133 N terminal like HGTP_anticodon PF03129.20 RUS78832.1 - 0.015 15.5 0.8 0.023 14.9 0.0 1.7 2 0 0 2 2 2 0 Anticodon binding domain Hira PF07569.11 RUS78832.1 - 0.11 12.2 0.0 1.3 8.7 0.0 2.7 2 1 2 4 4 4 0 TUP1-like enhancer of split Frag1 PF10277.9 RUS78833.1 - 2e-55 187.7 35.6 3.4e-34 118.3 15.0 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family DUF4287 PF14117.6 RUS78833.1 - 0.0028 17.8 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4287) DUF420 PF04238.12 RUS78833.1 - 0.086 13.1 8.6 3 8.2 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF420) TetR_C_23 PF17931.1 RUS78833.1 - 0.11 12.6 1.8 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DDE_3 PF13358.6 RUS78833.1 - 0.24 11.2 3.7 46 3.8 0.0 3.2 3 0 0 3 3 3 0 DDE superfamily endonuclease CytochromB561_N PF09786.9 RUS78833.1 - 0.67 8.9 5.8 1.7 7.6 1.3 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal DUF2178 PF09946.9 RUS78833.1 - 0.68 10.1 5.9 20 5.4 0.2 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Ribosomal_L30 PF00327.20 RUS78834.1 - 3.4e-08 33.2 0.3 1.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CD34_antigen PF06365.12 RUS78835.1 - 4.4e-05 23.2 0.1 4.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Orf78 PF06024.12 RUS78835.1 - 4.5e-05 23.7 0.4 6.5e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Orf78 (ac78) SKG6 PF08693.10 RUS78835.1 - 6.6e-05 22.2 1.7 6.6e-05 22.2 1.7 1.7 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 RUS78835.1 - 0.00013 21.5 1.1 0.00018 21.0 1.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Shisa PF13908.6 RUS78835.1 - 0.0002 21.7 0.4 0.00025 21.4 0.4 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 RUS78835.1 - 0.00034 19.6 0.2 0.00037 19.5 0.2 1.0 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 RUS78835.1 - 0.00039 21.2 0.1 0.0013 19.6 0.1 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RUS78835.1 - 0.00079 19.3 5.1 0.00079 19.3 5.1 1.5 1 1 0 1 1 1 1 TMEM154 protein family Insulin_TMD PF17870.1 RUS78835.1 - 0.0014 18.6 0.4 0.0026 17.8 0.4 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF4448 PF14610.6 RUS78835.1 - 0.0015 18.4 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Peptidase_M56 PF05569.11 RUS78835.1 - 0.0029 16.9 1.1 0.0036 16.5 1.1 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 7TM_GPCR_Srd PF10317.9 RUS78835.1 - 0.003 16.8 0.1 0.0037 16.5 0.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Protocadherin PF08374.11 RUS78835.1 - 0.003 17.6 1.7 0.0032 17.5 1.2 1.3 1 1 0 1 1 1 1 Protocadherin DUF3377 PF11857.8 RUS78835.1 - 0.0038 17.1 1.4 0.0038 17.1 1.4 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3377) DAG1 PF05454.11 RUS78835.1 - 0.0043 16.5 0.1 0.0046 16.4 0.1 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TAS2R PF05296.13 RUS78835.1 - 0.0051 16.0 0.4 0.0067 15.6 0.4 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) TMEM51 PF15345.6 RUS78835.1 - 0.0067 16.3 0.2 0.0076 16.1 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Mid2 PF04478.12 RUS78835.1 - 0.0078 16.1 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor 7TM_GPCR_Srv PF10323.9 RUS78835.1 - 0.0084 15.5 0.2 0.0095 15.3 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 RUS78835.1 - 0.011 15.1 0.7 0.013 14.8 0.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw BatD PF13584.6 RUS78835.1 - 0.011 14.6 0.1 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance AMA-1 PF02430.15 RUS78835.1 - 0.014 14.4 0.2 0.017 14.1 0.2 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Trp_oprn_chp PF09534.10 RUS78835.1 - 0.017 14.9 0.6 0.02 14.7 0.6 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SARAF PF06682.12 RUS78835.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ABC2_membrane_3 PF12698.7 RUS78835.1 - 0.019 14.1 0.3 0.022 13.9 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Stevor PF17410.2 RUS78835.1 - 0.023 14.3 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 RUS78835.1 - 0.025 14.5 0.4 0.03 14.2 0.4 1.1 1 0 0 1 1 1 0 Rifin DUF4064 PF13273.6 RUS78835.1 - 0.027 14.8 0.9 0.05 13.9 0.8 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3619 PF12279.8 RUS78835.1 - 0.033 14.5 0.5 0.061 13.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) Gaa1 PF04114.14 RUS78835.1 - 0.038 13.0 0.3 0.045 12.8 0.3 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF4834 PF16118.5 RUS78835.1 - 0.041 14.9 0.2 0.041 14.9 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF4307 PF14155.6 RUS78835.1 - 0.046 13.6 3.8 0.36 10.7 2.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4307) YajC PF02699.15 RUS78835.1 - 0.053 13.4 1.0 0.11 12.4 1.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4366 PF14283.6 RUS78835.1 - 0.059 13.4 0.9 0.16 12.0 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) PspB PF06667.12 RUS78835.1 - 0.075 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF2615 PF11027.8 RUS78835.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Cadherin_C_2 PF16492.5 RUS78835.1 - 0.089 13.6 0.2 0.15 12.8 0.2 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal OSTMP1 PF09777.9 RUS78835.1 - 0.09 12.2 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor MLANA PF14991.6 RUS78835.1 - 0.1 12.9 0.2 0.2 11.9 0.2 1.6 1 1 0 1 1 1 0 Protein melan-A GRP PF07172.11 RUS78835.1 - 0.13 13.0 1.0 6.4 7.5 0.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family Cytomega_UL20A PF05984.12 RUS78835.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.0 2 1 0 2 2 2 0 Cytomegalovirus UL20A protein Sulf_transp PF04143.14 RUS78835.1 - 0.18 11.3 0.2 0.31 10.5 0.2 1.3 1 1 0 1 1 1 0 Sulphur transport ASFV_J13L PF05568.11 RUS78835.1 - 0.19 11.5 1.9 0.21 11.3 1.5 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.11 RUS78835.1 - 0.19 11.3 4.4 0.16 11.6 2.6 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family MAP17 PF15807.5 RUS78835.1 - 0.27 11.5 3.5 0.56 10.5 0.1 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF515 PF04415.12 RUS78835.1 - 0.36 9.2 8.8 0.11 10.9 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF515) DUF3357 PF11837.8 RUS78835.1 - 0.62 10.5 5.9 0.21 12.1 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF1180 PF06679.12 RUS78835.1 - 2.9 8.3 8.0 0.24 11.8 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MHYT PF03707.16 RUS78835.1 - 3.2 8.0 5.8 2.9 8.1 0.7 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat SDF PF00375.18 RUS78836.1 - 8.4e-35 120.5 11.7 9.5e-35 120.3 11.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MATalpha_HMGbox PF04769.12 RUS78838.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF5357 PF17310.2 RUS78838.1 - 0.29 9.6 1.6 0.78 8.2 1.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5357) Acetyltransf_1 PF00583.25 RUS78839.1 - 1.9e-15 57.1 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS78839.1 - 5.6e-09 36.3 0.1 8.1e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS78839.1 - 8.6e-08 32.2 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RUS78839.1 - 0.00031 20.9 0.5 0.00064 19.9 0.5 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RUS78839.1 - 0.0022 17.7 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS78839.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RUS78839.1 - 0.0092 16.1 0.0 0.018 15.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4189 PF13827.6 RUS78839.1 - 0.0094 16.5 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4189) Acetyltransf_3 PF13302.7 RUS78839.1 - 0.028 15.1 0.0 0.036 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 RUS78839.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain zf-C2H2 PF00096.26 RUS78841.1 - 3e-28 96.7 87.5 0.00069 19.9 2.0 12.1 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78841.1 - 1.5e-26 91.6 80.7 4.5e-07 30.0 0.9 13.2 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78841.1 - 2.9e-25 86.8 88.0 0.00098 19.8 0.2 12.5 12 0 0 12 12 12 9 C2H2-type zinc finger zf-Di19 PF05605.12 RUS78841.1 - 2e-12 47.2 49.7 2.3e-05 24.6 3.1 8.0 5 3 3 8 8 8 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RUS78841.1 - 3e-08 33.8 36.3 0.02 15.2 0.6 9.7 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 RUS78841.1 - 8.7e-07 29.7 39.9 0.058 14.1 6.6 6.9 3 2 1 5 5 5 4 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RUS78841.1 - 0.00033 20.3 0.1 0.00033 20.3 0.1 10.2 12 0 0 12 12 12 5 zinc-finger C2H2-type Chordopox_RPO7 PF05864.12 RUS78841.1 - 0.16 12.3 0.6 2 8.7 0.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GAGA PF09237.11 RUS78841.1 - 0.3 10.9 11.3 0.58 10.0 2.7 4.4 4 0 0 4 4 4 0 GAGA factor zf-met PF12874.7 RUS78841.1 - 0.56 10.7 42.8 1.6 9.2 0.1 8.9 9 0 0 9 9 9 0 Zinc-finger of C2H2 type DUF5526 PF17664.1 RUS78842.1 - 3.9e-21 75.3 8.4 3.9e-21 75.3 8.4 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5526) DUF3887 PF13026.6 RUS78842.1 - 0.015 16.1 2.0 3.6 8.5 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) LMBR1 PF04791.16 RUS78842.1 - 2.7 6.8 5.1 2.9 6.7 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C4 PF00105.18 RUS78843.1 - 1.8e-29 102.0 15.0 1.8e-29 102.0 15.0 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS78843.1 - 1.9e-23 83.1 0.4 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor PEN-2 PF10251.9 RUS78844.1 - 2.2e-38 130.5 2.3 2.5e-38 130.4 2.3 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase FA_hydroxylase PF04116.13 RUS78846.1 - 9e-25 87.6 20.6 9e-25 87.6 20.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ATP-synt_G PF04718.15 RUS78847.1 - 3.9e-20 72.5 0.0 4.6e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF3477 PF11963.8 RUS78847.1 - 0.034 13.4 0.0 0.039 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) LRR_4 PF12799.7 RUS78848.1 - 2.2e-14 53.3 10.4 0.001 19.4 0.2 5.2 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS78848.1 - 1.3e-08 34.5 0.4 8.7e-05 22.1 0.0 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 RUS78848.1 - 1.1e-06 28.3 5.8 0.061 13.1 0.0 4.7 3 1 1 4 4 4 3 Leucine rich repeat Ubiquitin_2 PF14560.6 RUS78848.1 - 0.0012 19.3 0.1 0.003 18.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 RUS78848.1 - 0.0042 16.8 0.1 0.023 14.4 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin family Cohesin PF00963.18 RUS78848.1 - 0.05 13.8 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Cohesin domain DUF4961 PF16328.5 RUS78848.1 - 0.17 11.2 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) Mito_fiss_Elm1 PF06258.11 RUS78849.1 - 0.065 12.4 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Pkinase PF00069.25 RUS78850.1 - 4.1e-21 75.5 0.0 6.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS78850.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS78850.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS78850.1 - 0.041 13.2 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MT PF12777.7 RUS78851.1 - 2.7e-05 23.4 0.0 3.2e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Thioredoxin PF00085.20 RUS78852.1 - 4.3e-07 29.9 0.2 5.4e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3570 PF12094.8 RUS78853.1 - 0.045 12.5 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) Peptidase_C65 PF10275.9 RUS78853.1 - 0.062 12.7 0.1 0.12 11.8 0.0 1.4 2 0 0 2 2 2 0 Peptidase C65 Otubain HHH_7 PF14635.6 RUS78853.1 - 0.069 13.5 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_transf_7N PF13733.6 RUS78856.1 - 5.4e-46 155.6 0.0 7e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS78856.1 - 1.1e-18 66.6 1.0 1.6e-18 66.1 1.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase IQ PF00612.27 RUS78857.1 - 9.6e-19 65.4 0.4 1.9e-05 24.0 0.1 3.2 3 0 0 3 3 3 3 IQ calmodulin-binding motif Yop-YscD_cpl PF16697.5 RUS78857.1 - 0.00029 21.1 0.1 0.63 10.4 0.0 2.2 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain DapB_N PF01113.20 RUS78857.1 - 0.031 14.4 1.3 1.9 8.6 0.1 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus VanY PF02557.17 RUS78857.1 - 0.053 13.3 1.4 0.12 12.2 0.9 1.6 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Seipin PF06775.14 RUS78857.1 - 0.14 12.2 0.5 5.4 7.1 0.5 2.2 1 1 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) DUF4330 PF14221.6 RUS78857.1 - 1 9.5 4.6 1.3 9.2 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) IQ PF00612.27 RUS78858.1 - 1.1e-12 46.6 0.1 7e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Yop-YscD_cpl PF16697.5 RUS78858.1 - 0.001 19.4 0.0 1.4 9.2 0.0 2.1 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Tetraspanin PF00335.20 RUS78859.1 - 9e-45 153.1 12.2 1e-44 152.9 12.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF5353 PF17304.2 RUS78859.1 - 0.0034 17.1 0.8 0.0079 15.9 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5353) Prominin PF05478.11 RUS78859.1 - 0.17 9.8 1.7 0.29 9.1 1.7 1.4 1 0 0 1 1 1 0 Prominin Glyco_transf_10 PF00852.19 RUS78860.1 - 1.7e-49 167.9 0.1 2.2e-49 167.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS78860.1 - 0.00058 20.3 0.8 0.0016 18.9 0.1 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal 7tm_1 PF00001.21 RUS78861.1 - 2.4e-52 177.9 7.9 3e-52 177.6 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78861.1 - 7.7e-05 22.4 9.0 0.00018 21.2 9.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS78861.1 - 0.00082 18.8 8.2 0.0015 18.0 8.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0715 PF17094.5 RUS78861.1 - 0.009 16.6 1.4 0.009 16.6 1.4 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0715) 7tm_4 PF13853.6 RUS78861.1 - 0.011 15.5 1.9 0.011 15.5 1.9 2.1 1 1 1 2 2 2 0 Olfactory receptor DUF2970 PF11174.8 RUS78861.1 - 0.075 12.9 2.3 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF3671 PF12420.8 RUS78861.1 - 6 7.0 6.7 0.45 10.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function Rad21_Rec8_N PF04825.13 RUS78863.1 - 1.4e-19 70.3 0.0 4e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RUS78863.1 - 0.0011 18.3 0.0 0.003 16.8 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein p450 PF00067.22 RUS78864.1 - 1.9e-96 323.6 0.0 2.5e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDC45 PF02724.14 RUS78864.1 - 0.0029 16.0 19.8 0.0041 15.5 19.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4637 PF15470.6 RUS78864.1 - 0.0039 16.9 4.7 0.0082 15.9 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 RUS78864.1 - 0.0071 14.5 38.0 0.01 14.0 38.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 RUS78864.1 - 0.0087 14.6 14.1 0.012 14.1 14.1 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2457 PF10446.9 RUS78864.1 - 0.15 11.2 41.3 0.26 10.4 41.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS78864.1 - 0.27 9.4 27.9 0.39 8.9 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 RUS78864.1 - 1 8.5 11.6 1.7 7.8 11.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 RUS78864.1 - 1.4 8.1 21.5 2 7.7 21.5 1.1 1 0 0 1 1 1 0 BUD22 Cnd2 PF05786.14 RUS78864.1 - 1.5 7.4 19.2 2.2 6.8 19.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SGT1 PF07093.11 RUS78864.1 - 1.7 7.0 12.2 2.5 6.4 12.2 1.2 1 0 0 1 1 1 0 SGT1 protein SDA1 PF05285.12 RUS78864.1 - 1.9 7.8 26.7 2.8 7.3 26.7 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 RUS78864.1 - 5.5 6.3 8.9 7.7 5.8 8.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.12 RUS78864.1 - 5.9 6.1 48.1 37 3.5 48.1 2.0 1 1 0 1 1 1 0 NOA36 protein 7tm_1 PF00001.21 RUS78865.1 - 3.8e-05 23.2 6.0 4.7e-05 22.8 6.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78865.1 - 0.14 11.7 13.3 0.17 11.5 13.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS78866.1 - 1.7e-45 155.4 16.3 2.6e-45 154.8 16.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS78866.1 - 1.3e-07 31.3 14.1 2.2e-07 30.5 14.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS78866.1 - 0.0014 18.4 10.0 0.0014 18.4 10.0 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS78866.1 - 7.9 6.0 25.9 0.34 10.5 16.5 2.9 2 2 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx SH3_1 PF00018.28 RUS78867.1 - 1.5e-23 82.1 0.7 6.5e-11 41.7 0.1 2.2 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RUS78867.1 - 2.1e-18 65.7 0.1 6.7e-09 35.3 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 RUS78867.1 - 4.8e-18 64.8 1.6 4.4e-11 42.5 0.2 2.1 2 0 0 2 2 2 2 Variant SH3 domain PUA_3 PF17785.1 RUS78867.1 - 0.0091 15.8 0.1 0.93 9.4 0.0 2.4 2 0 0 2 2 2 2 PUA-like domain WW PF00397.26 RUS78868.1 - 1.4e-14 53.9 0.0 2.4e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 RUS78868.1 - 1.7e-07 31.5 0.0 4.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain GCP_N_terminal PF17681.1 RUS78868.1 - 0.0048 16.6 1.7 0.0048 16.6 1.7 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Osmo_MPGsynth PF09488.10 RUS78868.1 - 0.071 11.8 0.5 0.14 10.8 0.5 1.4 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DASH_Dad2 PF08654.10 RUS78868.1 - 4.7 7.7 7.8 32 5.0 1.5 3.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Reprolysin_2 PF13574.6 RUS78869.1 - 3.6e-22 79.2 0.0 5.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS78869.1 - 6e-19 69.0 0.0 6e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS78869.1 - 4.1e-10 40.3 0.1 8.9e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 RUS78869.1 - 8.8e-09 36.0 18.7 8.8e-09 36.0 18.7 1.7 2 0 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 RUS78869.1 - 5.8e-08 32.6 0.0 9.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS78869.1 - 2.2e-07 31.2 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 RUS78869.1 - 5.9e-07 29.6 0.1 1.2e-05 25.4 0.0 2.8 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease DUF4215 PF13948.6 RUS78869.1 - 0.018 15.5 4.5 0.018 15.5 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) Peptidase_M1 PF01433.20 RUS78869.1 - 0.12 11.9 0.2 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Peptidase family M1 domain Integrase_H2C2 PF17921.1 RUS78870.1 - 1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain PARP PF00644.20 RUS78871.1 - 1.8e-37 128.9 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RUS78871.1 - 0.038 14.1 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Pinin_SDK_N PF04697.13 RUS78872.1 - 1.4e-33 116.5 1.9 1.4e-33 116.5 1.9 4.6 2 1 2 4 4 4 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.13 RUS78872.1 - 9.9e-29 100.0 19.7 9.9e-29 100.0 19.7 5.3 2 2 2 5 5 5 1 pinin/SDK/memA/ protein conserved region DUF3853 PF12964.7 RUS78872.1 - 0.029 14.5 0.3 9.9 6.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Laminin_G_3 PF13385.6 RUS78873.1 - 1.2e-09 38.5 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PAN_2 PF08276.11 RUS78873.1 - 0.032 14.3 0.2 0.066 13.3 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain DUF5370 PF17340.2 RUS78873.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5370) DUF1080 PF06439.11 RUS78873.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Glyco_hydro_1 PF00232.18 RUS78874.1 - 3.4e-73 246.6 0.4 3.9e-73 246.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 RUS78874.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_1 PF00232.18 RUS78875.1 - 0 1618.1 12.0 1.7e-170 567.4 4.6 4.1 4 0 0 4 4 4 4 Glycosyl hydrolase family 1 Cellulase PF00150.18 RUS78875.1 - 2.1e-07 30.7 12.5 0.0063 16.0 0.5 6.0 6 0 0 6 6 6 4 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL_2 PF13472.6 RUS78875.1 - 0.001 19.5 0.0 1.8 8.9 0.0 4.5 5 0 0 5 5 5 1 GDSL-like Lipase/Acylhydrolase family DUF3258 PF11646.8 RUS78875.1 - 0.29 11.3 0.8 5.4 7.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF3258 HMMR_N PF15905.5 RUS78876.1 - 2.5e-05 23.9 19.7 2.5e-05 23.9 19.7 4.6 2 2 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 RUS78876.1 - 0.00046 19.6 80.3 0.019 14.4 9.0 5.8 2 2 3 5 5 5 4 Growth-arrest specific micro-tubule binding DUF745 PF05335.13 RUS78876.1 - 0.0011 18.7 2.9 0.0011 18.7 2.9 5.9 1 1 7 8 8 8 3 Protein of unknown function (DUF745) SHE3 PF17078.5 RUS78876.1 - 0.0013 18.5 20.3 0.0013 18.5 20.3 5.7 2 2 2 4 4 2 1 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 RUS78876.1 - 0.002 18.1 43.1 0.0061 16.6 0.4 7.6 3 2 4 8 8 8 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RUS78876.1 - 0.0022 18.0 98.3 0.013 15.5 21.6 6.7 1 1 5 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 RUS78876.1 - 0.0022 18.2 16.9 0.0022 18.2 16.9 6.1 1 1 4 6 6 6 2 JNK_SAPK-associated protein-1 ATG16 PF08614.11 RUS78876.1 - 0.0023 18.2 79.1 0.0025 18.1 11.2 6.1 2 2 4 6 6 6 3 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 RUS78876.1 - 0.0024 18.1 14.0 0.0024 18.1 14.0 6.5 1 1 3 5 5 4 1 Tropomyosin like Filament PF00038.21 RUS78876.1 - 0.0028 17.3 75.2 0.46 10.0 16.0 5.8 1 1 1 3 3 3 2 Intermediate filament protein Nsp1_C PF05064.13 RUS78876.1 - 0.015 15.1 1.2 0.015 15.1 1.2 6.3 3 3 3 7 7 7 0 Nsp1-like C-terminal region BRE1 PF08647.11 RUS78876.1 - 0.017 15.2 65.7 0.78 9.9 7.4 8.0 2 2 5 8 8 8 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 RUS78876.1 - 0.026 15.1 3.5 0.026 15.1 3.5 7.5 2 2 5 8 8 8 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COG2 PF06148.11 RUS78876.1 - 0.032 14.3 0.9 0.032 14.3 0.9 6.4 2 2 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 RUS78876.1 - 0.034 13.0 87.5 0.11 11.3 12.3 5.5 1 1 1 5 5 5 0 Spc7 kinetochore protein Fez1 PF06818.15 RUS78876.1 - 0.039 14.4 80.7 3.8 7.9 11.6 5.3 1 1 3 4 4 4 0 Fez1 ERM PF00769.19 RUS78876.1 - 0.075 12.8 78.5 0.025 14.4 21.9 5.4 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DUF4342 PF14242.6 RUS78876.1 - 0.1 12.6 1.6 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) ADIP PF11559.8 RUS78876.1 - 0.11 12.5 75.2 0.091 12.8 7.5 7.7 1 1 6 8 8 8 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 RUS78876.1 - 0.18 11.2 80.7 0.11 12.0 16.1 5.4 1 1 4 5 5 5 0 Golgin subfamily A member 5 DUF4472 PF14739.6 RUS78876.1 - 0.22 12.2 61.4 0.83 10.4 5.1 8.0 1 1 5 7 7 7 0 Domain of unknown function (DUF4472) MscS_porin PF12795.7 RUS78876.1 - 1 8.9 46.7 0.025 14.1 7.8 6.9 2 2 4 7 7 5 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 RUS78876.1 - 1.3 9.1 77.0 0.4 10.8 11.5 5.9 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 RUS78876.1 - 1.6 8.3 80.2 0.56 9.8 11.0 5.6 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease CCDC144C PF14915.6 RUS78876.1 - 2.5 7.1 89.8 0.091 11.9 24.6 4.7 1 1 3 4 4 4 0 CCDC144C protein coiled-coil region Leu_zip PF15294.6 RUS78876.1 - 4.2 6.8 72.9 0.76 9.2 4.3 5.5 1 1 4 6 6 6 0 Leucine zipper WEMBL PF05701.11 RUS78876.1 - 8.2 5.0 69.1 0.033 12.9 11.3 4.1 1 1 1 3 3 3 0 Weak chloroplast movement under blue light Ank_5 PF13857.6 RUS78878.1 - 2.9e-14 53.0 0.6 1.9e-07 31.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS78878.1 - 8.6e-14 51.7 1.2 1.2e-05 25.7 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS78878.1 - 6e-12 45.5 1.4 4.6e-05 23.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RUS78878.1 - 2.2e-10 40.9 0.0 0.00078 20.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS78878.1 - 3e-09 36.4 0.2 0.00019 21.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat PAT1 PF09770.9 RUS78879.1 - 0.6 8.3 21.8 0.96 7.6 21.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Roughex PF06020.11 RUS78879.1 - 1.2 8.2 9.8 2 7.4 9.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Tim54 PF11711.8 RUS78879.1 - 5.5 5.7 11.1 8.1 5.1 11.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Filament PF00038.21 RUS78880.1 - 0.0079 15.8 28.4 0.011 15.4 28.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF3496 PF12001.8 RUS78880.1 - 0.59 10.5 9.5 6.8 7.1 6.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Metal_resist PF13801.6 RUS78880.1 - 2.6 8.3 15.9 15 5.8 2.5 3.6 3 0 0 3 3 3 0 Heavy-metal resistance Fez1 PF06818.15 RUS78880.1 - 6.8 7.1 31.5 0.057 13.9 19.0 2.1 1 1 1 2 2 2 0 Fez1 LMBR1 PF04791.16 RUS78881.1 - 0.019 13.9 1.7 0.022 13.7 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tox-ART-HYE1 PF15634.6 RUS78881.1 - 0.1 11.9 3.4 0.056 12.7 1.7 1.5 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase CDK5_activator PF03261.15 RUS78881.1 - 0.18 11.3 3.5 0.22 11.0 3.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CpxA_peri PF16527.5 RUS78881.1 - 3.3 8.1 7.7 2.1 8.7 2.0 2.2 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain DUF4407 PF14362.6 RUS78881.1 - 3.5 6.9 8.6 5.1 6.4 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EF-hand_7 PF13499.6 RUS78887.1 - 7.5e-16 58.3 4.6 6e-10 39.4 1.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS78887.1 - 4e-12 44.8 7.4 0.00023 20.5 0.5 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS78887.1 - 3.5e-11 42.1 7.8 9.9e-05 22.0 0.3 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RUS78887.1 - 3e-10 39.1 7.5 0.001 18.5 0.7 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS78887.1 - 3.5e-05 23.6 3.8 0.0002 21.1 0.5 3.1 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS78887.1 - 0.0024 18.2 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3567 PF12091.8 RUS78887.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) DIPSY PF11763.8 RUS78887.1 - 0.13 12.4 0.6 0.91 9.7 0.1 2.0 1 1 1 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal Arrestin_N PF00339.29 RUS78889.1 - 4.7e-41 140.2 0.0 1.1e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS78889.1 - 8.4e-18 65.1 0.0 5.1e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS78889.1 - 0.0016 17.7 0.0 0.0094 15.2 0.1 2.1 3 0 0 3 3 3 1 Rgp1 Vps26 PF03643.15 RUS78889.1 - 0.042 12.8 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 DUF3330 PF11809.8 RUS78889.1 - 0.048 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) EF-hand_7 PF13499.6 RUS78890.1 - 8.1e-06 26.2 0.2 0.009 16.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS78890.1 - 0.0032 17.3 0.1 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS78890.1 - 0.0034 16.8 0.0 0.0034 16.8 0.0 2.1 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 RUS78890.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 EF hand zf-C2H2 PF00096.26 RUS78891.1 - 3.1e-21 74.6 27.6 9.6e-06 25.8 0.8 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78891.1 - 1e-19 70.0 32.4 1.3e-06 28.6 2.7 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS78891.1 - 2.3e-17 62.2 26.2 0.00018 22.1 0.5 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS78891.1 - 1.5e-08 34.7 14.7 0.068 13.5 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS78891.1 - 5e-08 32.8 27.0 0.0042 17.0 0.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger XPA_N PF01286.18 RUS78891.1 - 1.8e-05 24.7 20.3 2.7 8.1 0.1 7.1 5 1 4 9 9 9 1 XPA protein N-terminal zf_ZIC PF18366.1 RUS78891.1 - 1.9e-05 24.6 11.5 0.72 10.0 0.1 4.5 3 1 1 4 4 4 3 Zic proteins zinc finger domain zf_UBZ PF18439.1 RUS78891.1 - 2.1e-05 24.0 11.4 2.6 7.7 0.2 4.3 4 0 0 4 4 4 4 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS78891.1 - 0.00015 22.1 16.9 0.0057 17.0 0.3 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RUS78891.1 - 0.00023 21.0 12.7 1.8 8.6 0.3 4.8 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-Di19 PF05605.12 RUS78891.1 - 0.00024 21.3 18.1 0.4 11.0 0.1 3.2 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RUS78891.1 - 0.00025 21.0 18.0 0.092 12.8 2.8 4.1 4 0 0 4 4 4 3 BED zinc finger Zn-ribbon_8 PF09723.10 RUS78891.1 - 0.0012 18.9 15.2 0.93 9.7 2.4 4.0 2 2 2 4 4 4 2 Zinc ribbon domain zf-H2C2_5 PF13909.6 RUS78891.1 - 0.0012 18.5 23.6 0.31 10.8 8.0 4.5 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS78891.1 - 0.0017 18.1 19.1 0.28 11.0 0.1 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-AN1 PF01428.16 RUS78891.1 - 0.0017 18.5 19.6 0.082 13.1 1.6 4.2 4 0 0 4 4 4 1 AN1-like Zinc finger Endonuclease_7 PF02945.15 RUS78891.1 - 0.0025 17.7 8.6 0.14 12.1 1.1 2.2 2 0 0 2 2 2 2 Recombination endonuclease VII GAGA PF09237.11 RUS78891.1 - 0.0075 16.1 6.3 0.67 9.8 0.2 3.2 2 1 1 3 3 3 1 GAGA factor C1_1 PF00130.22 RUS78891.1 - 0.012 15.4 12.4 0.42 10.5 5.0 3.5 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 RUS78891.1 - 0.013 15.9 16.4 0.61 10.6 1.8 4.1 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger HNH_5 PF14279.6 RUS78891.1 - 0.046 13.6 11.5 1.2 9.0 0.9 3.9 2 2 0 2 2 2 0 HNH endonuclease zinc_ribbon_15 PF17032.5 RUS78891.1 - 0.049 14.4 1.6 0.049 14.4 1.6 2.4 2 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 RUS78891.1 - 0.051 14.2 12.4 0.54 10.9 3.1 3.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 RUS78891.1 - 0.061 13.2 14.4 2 8.4 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger HTH_1 PF00126.27 RUS78891.1 - 0.068 13.1 0.3 11 6.0 0.1 2.5 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family zf_C2H2_ZHX PF18387.1 RUS78891.1 - 0.11 12.2 0.3 0.11 12.2 0.3 4.0 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain ADK_lid PF05191.14 RUS78891.1 - 0.39 10.7 9.6 7.9 6.6 0.5 3.1 2 2 2 4 4 4 0 Adenylate kinase, active site lid CpXC PF14353.6 RUS78891.1 - 0.42 10.7 11.1 6.1 6.9 0.1 3.7 2 2 1 3 3 3 0 CpXC protein FYDLN_acid PF09538.10 RUS78891.1 - 0.75 10.5 6.2 57 4.5 0.0 3.8 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) DZR PF12773.7 RUS78891.1 - 0.76 9.9 14.2 5.4 7.1 5.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_2 PF12756.7 RUS78891.1 - 0.97 9.8 16.3 7.9 6.9 1.5 4.0 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 RUS78891.1 - 1 9.6 13.8 7.5 6.9 0.3 3.8 3 1 1 4 4 4 0 LIM domain zinc-ribbons_6 PF07191.12 RUS78891.1 - 1.2 9.2 12.4 9.9 6.2 1.0 3.3 2 2 1 3 3 3 0 zinc-ribbons TRAP-delta PF05404.12 RUS78891.1 - 2 7.9 11.8 25 4.4 0.9 3.9 1 1 2 3 3 3 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) MLTD_N PF06474.12 RUS78891.1 - 2.3 8.5 7.5 1.7e+02 2.5 0.1 4.6 2 1 3 5 5 5 0 MltD lipid attachment motif zf-FCS PF06467.14 RUS78891.1 - 2.6 8.1 17.3 11 6.1 0.5 4.3 3 1 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif DUF629 PF04780.12 RUS78891.1 - 2.6 6.4 20.1 0.24 9.9 3.5 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF629) Sprouty PF05210.13 RUS78891.1 - 4.4 7.7 9.3 1.6 9.1 3.1 2.5 2 2 1 3 3 3 0 Sprouty protein (Spry) TFIIS_C PF01096.18 RUS78891.1 - 7 6.6 18.5 6.3 6.7 2.0 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.13 RUS78891.1 - 8.8 6.1 10.8 11 5.8 0.3 3.6 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Peptidase_M13_N PF05649.13 RUS78892.1 - 1.6e-67 228.9 0.2 2.9e-67 228.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS78892.1 - 1.8e-26 93.0 0.1 3.7e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 GPI2 PF06432.11 RUS78893.1 - 3.1e-68 230.3 15.0 3.5e-68 230.1 15.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase MBT PF02820.18 RUS78893.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 mbt repeat DUF2371 PF10177.9 RUS78893.1 - 0.0055 16.9 0.1 0.011 16.0 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) HAUS6_N PF14661.6 RUS78894.1 - 0.041 13.5 0.3 0.066 12.8 0.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NAGLU_N PF12971.7 RUS78895.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Agenet PF05641.12 RUS78896.1 - 0.0019 18.6 1.2 0.077 13.5 0.0 2.8 3 0 0 3 3 3 1 Agenet domain NIBRIN_BRCT_II PF16508.5 RUS78896.1 - 0.13 12.6 0.2 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Sprouty PF05210.13 RUS78897.1 - 5.9e-18 65.2 32.0 9.6e-18 64.5 32.0 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) Mucin-like PF16058.5 RUS78898.1 - 0.0011 19.0 10.3 0.0011 19.0 10.3 2.3 2 0 0 2 2 2 2 Mucin-like APC_basic PF05956.11 RUS78898.1 - 0.67 9.3 8.4 1.2 8.6 5.7 2.0 1 1 1 2 2 2 0 APC basic domain CDC45 PF02724.14 RUS78899.1 - 0.00023 19.6 23.9 0.00029 19.3 23.9 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS78899.1 - 0.053 13.0 37.4 0.065 12.6 37.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS78899.1 - 0.12 10.5 38.2 0.15 10.3 38.2 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RUS78899.1 - 0.65 8.4 27.8 0.78 8.1 27.8 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 RUS78899.1 - 7.6 6.3 9.1 9.7 6.0 9.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Beta-lactamase PF00144.24 RUS78900.1 - 1.9e-41 142.4 0.1 2.5e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase SyrA PF11089.8 RUS78900.1 - 0.01 15.9 0.6 0.024 14.7 0.6 1.6 1 0 0 1 1 1 0 Exopolysaccharide production repressor SPC22 PF04573.12 RUS78901.1 - 1.9e-57 193.5 0.2 2.1e-57 193.3 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit UCH PF00443.29 RUS78902.1 - 5.7e-60 203.0 3.5 6.6e-60 202.8 3.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS78902.1 - 1.8e-30 106.6 8.0 2.4e-30 106.2 8.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 RUS78902.1 - 0.00028 20.4 16.5 0.00051 19.6 13.3 2.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Med25 PF11232.8 RUS78902.1 - 0.0051 16.8 0.9 0.012 15.6 0.0 2.0 3 0 0 3 3 3 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Ribosomal_L21e PF01157.18 RUS78904.1 - 6.5e-38 128.7 1.6 1.6e-37 127.4 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L21e SepSecS PF05889.13 RUS78904.1 - 0.058 12.1 0.0 0.19 10.4 0.0 1.7 1 1 1 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3877 PF12993.7 RUS78905.1 - 0.026 14.4 0.5 0.029 14.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3466 PF11949.8 RUS78905.1 - 0.044 12.4 0.1 0.045 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) GATA PF00320.27 RUS78907.1 - 7.9e-28 95.8 17.4 5.2e-14 51.6 3.4 2.7 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RUS78907.1 - 8.6e-05 22.0 7.4 0.027 14.0 0.6 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 RUS78907.1 - 0.018 15.1 1.8 1.4 9.1 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 RUS78907.1 - 0.39 10.9 4.5 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 RUS78907.1 - 0.84 9.7 3.6 26 4.9 0.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 RUS78907.1 - 0.95 9.4 6.5 4.1 7.4 0.7 2.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 RUS78907.1 - 1 9.3 4.5 18 5.2 0.2 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.12 RUS78907.1 - 2.1 8.7 8.1 0.81 10.0 1.4 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Elf1 PF05129.13 RUS78907.1 - 2.3 8.3 6.4 6.5 6.9 0.2 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like GATA PF00320.27 RUS78908.1 - 2.3e-28 97.5 16.1 1.2e-14 53.6 5.2 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RUS78908.1 - 0.00013 21.4 7.4 0.06 12.9 1.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding zf-RRN7 PF11781.8 RUS78908.1 - 0.1 12.3 8.9 0.52 10.0 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 IR1-M PF12185.8 RUS78908.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Zn-ribbon_8 PF09723.10 RUS78908.1 - 0.18 11.9 3.6 4.3 7.5 0.3 2.7 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 RUS78908.1 - 0.55 10.3 6.4 4.4 7.4 0.8 2.6 1 1 0 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 RUS78908.1 - 1.1 8.7 5.2 0.65 9.4 0.2 3.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain eIF-5_eIF-2B PF01873.17 RUS78908.1 - 4 7.4 9.9 6.3 6.7 0.8 3.2 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 RUS78908.1 - 4.3 7.6 6.5 4.9 7.4 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SR-25 PF10500.9 RUS78908.1 - 6 6.4 24.3 9.5 5.8 8.9 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EphA2_TM PF14575.6 RUS78910.1 - 0.0059 17.5 0.0 0.032 15.1 0.0 2.2 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 RUS78910.1 - 0.082 12.9 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein DASH_Ask1 PF08655.10 RUS78911.1 - 0.00039 20.2 4.0 39 4.2 0.1 4.6 2 1 1 5 5 5 4 DASH complex subunit Ask1 GLTT PF01744.20 RUS78911.1 - 0.008 15.9 10.4 1.9 8.3 0.3 5.8 1 1 6 7 7 7 3 GLTT repeat (6 copies) DUF1827 PF08860.10 RUS78911.1 - 0.0081 16.4 2.2 12 6.2 0.3 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF1827) Stealth_CR1 PF17101.5 RUS78911.1 - 0.33 10.7 31.4 69 3.3 0.1 8.8 9 0 0 9 9 9 0 Stealth protein CR1, conserved region 1 DNA_pol_phi PF04931.13 RUS78912.1 - 0.0085 14.3 41.3 0.011 13.9 41.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RUS78912.1 - 0.013 13.8 23.6 0.015 13.6 23.6 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS78912.1 - 0.023 13.0 17.6 0.029 12.7 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS78912.1 - 0.11 11.0 17.7 0.13 10.7 17.7 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RUS78912.1 - 0.63 9.4 19.9 0.8 9.0 19.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 RUS78912.1 - 6.5 6.1 31.6 8.2 5.8 31.6 1.1 1 0 0 1 1 1 0 SDA1 OATP PF03137.20 RUS78913.1 - 9.7e-98 327.8 3.0 1.2e-97 327.5 3.0 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS78913.1 - 2.4e-17 62.9 22.8 3.7e-15 55.7 10.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS78913.1 - 0.00011 22.2 3.6 0.00024 21.2 3.6 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Phage_holin_3_6 PF07332.11 RUS78913.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.3 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III OATP PF03137.20 RUS78914.1 - 1.5e-09 36.8 2.2 5.2e-09 34.9 0.8 1.9 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family zf-C2HC_2 PF13913.6 RUS78915.1 - 2.6e-13 49.5 9.3 2.4e-09 36.9 0.9 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type DZR PF12773.7 RUS78915.1 - 0.0091 16.0 14.1 0.14 12.2 3.6 3.5 3 0 0 3 3 3 2 Double zinc ribbon zf-CHCC PF10276.9 RUS78915.1 - 0.046 13.8 0.4 0.046 13.8 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger domain CAP_N PF01213.19 RUS78915.1 - 0.079 12.4 0.8 0.12 11.8 0.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nairovirus_M PF07948.11 RUS78915.1 - 0.098 10.9 0.3 0.14 10.4 0.3 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-C2H2 PF00096.26 RUS78915.1 - 0.29 11.7 17.0 0.54 10.8 0.2 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS78915.1 - 0.33 11.5 6.7 1.4 9.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain FYDLN_acid PF09538.10 RUS78915.1 - 0.72 10.6 9.3 2.8 8.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.6 RUS78915.1 - 1.4 8.7 17.8 2.1 8.2 8.6 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Sulfatase PF00884.23 RUS78916.1 - 3.1e-77 260.0 0.6 3.7e-77 259.8 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS78916.1 - 0.0011 18.7 0.2 0.0077 15.9 0.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 RUS78916.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) 7tm_1 PF00001.21 RUS78917.1 - 8.6e-15 54.8 8.3 8.6e-15 54.8 8.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78917.1 - 1.8e-07 31.1 19.3 1.8e-07 31.1 19.3 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Sru PF10322.9 RUS78917.1 - 5.4e-05 22.7 6.4 5.4e-05 22.7 6.4 2.7 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srx PF10328.9 RUS78918.1 - 1.6e-05 24.7 16.9 2.2e-05 24.2 16.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS78918.1 - 0.0043 16.4 11.8 0.0043 16.4 11.8 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) FPN1 PF06963.12 RUS78918.1 - 0.0066 15.1 0.7 0.011 14.4 0.7 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Serpentine_r_xa PF03383.15 RUS78918.1 - 0.056 13.4 7.8 0.047 13.7 6.7 1.5 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Spheroidin PF05541.12 RUS78918.1 - 0.061 11.1 0.3 0.082 10.7 0.3 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein 60KD_IMP PF02096.20 RUS78918.1 - 0.58 10.0 3.8 5.5 6.9 0.1 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein SH3_1 PF00018.28 RUS78919.1 - 7.3e-15 54.3 0.2 1.1e-14 53.8 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS78919.1 - 6.7e-14 51.5 0.5 9.5e-14 51.0 0.5 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS78919.1 - 8.4e-13 47.8 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pneumo_att_G PF05539.11 RUS78919.1 - 7 6.1 8.8 8.6 5.8 8.8 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ank_2 PF12796.7 RUS78920.1 - 5.7e-06 26.8 0.1 8.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS78920.1 - 0.0013 19.2 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS78920.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 RUS78920.1 - 0.027 14.9 0.1 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat AICARFT_IMPCHas PF01808.18 RUS78921.1 - 3.3e-95 319.0 0.1 5.1e-95 318.3 0.1 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 RUS78921.1 - 2.5e-26 91.7 0.0 4.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain TERB2 PF15101.6 RUS78922.1 - 5.3e-27 95.2 0.0 7.4e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Telomere-associated protein TERB2 APC_u15 PF16636.5 RUS78922.1 - 1 9.8 5.3 0.28 11.7 2.0 1.7 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 LolB PF03550.14 RUS78923.1 - 0.053 13.6 0.1 6.8 6.7 0.1 2.4 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB tRNA_SAD PF07973.14 RUS78924.1 - 2.2e-10 40.4 0.3 6.2e-10 39.0 0.3 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 RUS78924.1 - 6.9e-05 21.6 0.0 9.7e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DUF1154 PF06631.11 RUS78924.1 - 0.073 13.1 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) WSC PF01822.19 RUS78925.1 - 2.7e-17 62.7 38.4 1.6e-05 25.0 8.8 6.4 6 0 0 6 6 5 3 WSC domain UL45 PF05473.12 RUS78925.1 - 5.9e-10 39.1 8.4 0.0064 16.1 0.5 3.6 3 0 0 3 3 3 3 UL45 protein, carbohydrate-binding C-type lectin-like Sushi PF00084.20 RUS78925.1 - 4.1e-07 30.5 10.8 7e-05 23.3 0.5 4.1 3 1 1 4 4 4 2 Sushi repeat (SCR repeat) Lectin_C PF00059.21 RUS78925.1 - 5.2e-06 27.2 7.8 0.068 13.9 0.1 5.8 5 1 1 6 6 6 2 Lectin C-type domain DUF4604 PF15377.6 RUS78925.1 - 0.00044 20.7 4.3 0.00066 20.1 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) eIF3_subunit PF08597.10 RUS78925.1 - 0.01 15.8 9.2 0.017 15.0 9.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MecA PF05389.12 RUS78925.1 - 0.073 12.7 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FAM91_C PF14648.6 RUS78925.1 - 0.088 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 FAM91 C-terminus CCDC106 PF15794.5 RUS78925.1 - 0.33 10.6 6.4 0.59 9.8 6.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 RUS78925.1 - 0.49 10.0 25.2 1.1 8.8 25.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.13 RUS78925.1 - 1.9 9.1 5.0 3.9 8.2 5.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 RUS78925.1 - 2 8.5 11.0 3.5 7.7 11.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.6 RUS78925.1 - 6.2 6.4 13.1 10 5.8 13.1 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF1387 PF07139.11 RUS78925.1 - 7.9 6.1 15.9 13 5.4 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) WSC PF01822.19 RUS78926.1 - 9e-10 38.6 0.8 1.4e-09 38.0 0.8 1.3 1 0 0 1 1 1 1 WSC domain DUF1644 PF07800.12 RUS78926.1 - 0.06 13.4 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) 7tm_1 PF00001.21 RUS78928.1 - 7.6e-05 22.2 21.1 0.00043 19.7 21.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS78928.1 - 0.00042 20.0 8.8 0.00042 20.0 8.8 2.1 2 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Myosin_tail_1 PF01576.19 RUS78929.1 - 0.00013 20.0 1.9 0.00014 19.8 1.9 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.9 RUS78929.1 - 0.0088 16.1 2.4 0.014 15.4 2.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 RUS78929.1 - 0.0092 14.6 0.8 0.01 14.4 0.8 1.2 1 0 0 1 1 1 1 Macoilin family ABC_tran_CTD PF16326.5 RUS78929.1 - 0.011 16.0 2.4 0.071 13.4 2.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Mod_r PF07200.13 RUS78929.1 - 0.016 15.3 6.2 0.023 14.8 6.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 RUS78929.1 - 0.018 15.5 3.5 0.037 14.5 3.5 1.6 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 RUS78929.1 - 0.028 15.0 5.1 0.042 14.4 5.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Ig_6 PF18452.1 RUS78929.1 - 0.038 13.5 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 RUS78929.1 - 0.11 13.1 0.2 0.37 11.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain E2F_CC-MB PF16421.5 RUS78929.1 - 0.12 12.7 3.0 0.16 12.4 1.8 1.8 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain ATG16 PF08614.11 RUS78929.1 - 0.16 12.2 10.9 0.35 11.1 10.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 RUS78929.1 - 0.16 12.2 5.1 0.22 11.7 5.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 RUS78929.1 - 0.68 10.6 3.5 1.3 9.7 3.2 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 RUS78929.1 - 0.94 9.5 8.0 0.27 11.2 1.6 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.6 RUS78929.1 - 1.6 8.8 8.7 0.25 11.4 0.3 2.5 2 1 1 3 3 3 0 FlxA-like protein Spc24 PF08286.11 RUS78929.1 - 1.9 8.8 7.5 1.8 8.8 5.8 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Baculo_PEP_C PF04513.12 RUS78930.1 - 0.0002 21.4 11.9 0.12 12.5 0.6 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 RUS78930.1 - 0.00035 20.7 8.7 0.024 14.7 8.8 2.7 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) GPAT_N PF14829.6 RUS78930.1 - 0.0026 17.7 2.3 0.5 10.4 0.3 2.8 1 1 2 3 3 3 2 Glycerol-3-phosphate acyltransferase N-terminal NPM1-C PF16276.5 RUS78930.1 - 0.0053 16.7 6.7 8.6 6.4 0.0 4.1 2 2 2 4 4 4 0 Nucleophosmin C-terminal domain DUF4200 PF13863.6 RUS78930.1 - 0.007 16.8 15.5 0.022 15.1 15.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) DUF4372 PF14294.6 RUS78930.1 - 0.0075 16.4 17.2 9 6.5 2.2 5.2 1 1 5 6 6 6 0 Domain of unknown function (DUF4372) DUF842 PF05811.13 RUS78930.1 - 0.0095 15.6 6.8 0.69 9.6 3.5 3.3 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF842) SF-assemblin PF06705.11 RUS78930.1 - 0.013 14.9 11.4 0.055 12.8 11.4 1.9 1 1 0 1 1 1 0 SF-assemblin/beta giardin Carbpep_Y_N PF05388.11 RUS78930.1 - 0.014 16.0 11.0 0.08 13.5 3.9 2.3 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Rx_N PF18052.1 RUS78930.1 - 0.022 15.0 13.7 2.7 8.3 0.7 3.8 1 1 1 2 2 2 0 Rx N-terminal domain Perilipin PF03036.16 RUS78930.1 - 0.024 13.7 14.0 0.11 11.5 5.3 2.3 1 1 1 2 2 2 0 Perilipin family Peptidase_S41_N PF11918.8 RUS78930.1 - 0.027 14.7 1.8 0.027 14.7 1.8 2.5 1 1 1 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF484 PF04340.12 RUS78930.1 - 0.049 13.3 15.5 1.2 8.8 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF484 NdhM PF10664.9 RUS78930.1 - 0.059 13.6 1.4 7.6 6.9 0.2 2.8 1 1 2 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M Prominin PF05478.11 RUS78930.1 - 0.079 10.9 21.4 0.39 8.6 5.8 2.0 1 1 1 2 2 2 0 Prominin Tweety PF04906.13 RUS78930.1 - 0.079 11.6 3.9 0.086 11.5 3.5 1.4 1 1 0 1 1 1 0 Tweety P22_AR_C PF10548.9 RUS78930.1 - 0.099 12.8 7.7 23 5.2 0.2 4.5 1 1 4 5 5 5 0 P22AR C-terminal domain DUF1059 PF06348.11 RUS78930.1 - 0.11 12.8 0.5 60 4.0 0.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1059) DUF4446 PF14584.6 RUS78930.1 - 0.12 12.3 12.5 0.98 9.4 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Tn7_Tnp_TnsA_C PF08721.11 RUS78930.1 - 0.15 12.7 9.4 0.14 12.8 3.2 2.3 1 1 1 2 2 2 0 TnsA endonuclease C terminal UMP1 PF05348.11 RUS78930.1 - 0.17 12.1 16.6 1.8 8.8 2.1 3.1 1 1 2 3 3 3 0 Proteasome maturation factor UMP1 Mu-like_Pro PF10123.9 RUS78930.1 - 0.51 9.8 4.5 1 8.8 4.5 1.6 1 1 0 1 1 1 0 Mu-like prophage I protein HTH_19 PF12844.7 RUS78930.1 - 0.51 10.4 14.4 11 6.1 4.8 4.0 1 1 2 3 3 3 0 Helix-turn-helix domain DUF445 PF04286.12 RUS78930.1 - 0.52 10.1 10.1 0.67 9.7 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COG2 PF06148.11 RUS78930.1 - 0.7 10.0 14.1 6.7 6.8 9.2 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 RUS78930.1 - 0.74 10.4 13.4 6.9 7.3 5.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PCRF PF03462.18 RUS78930.1 - 0.82 9.5 10.1 0.82 9.5 4.4 2.0 1 1 1 2 2 2 0 PCRF domain DUF5395 PF17373.2 RUS78930.1 - 1.1 10.0 8.0 39 5.0 0.3 3.9 1 1 3 4 4 4 0 Family of unknown function (DUF5395) PIN_8 PF18476.1 RUS78930.1 - 1.3 8.9 14.4 1.8 8.3 7.7 2.0 1 1 1 2 2 2 0 PIN like domain HigB-like_toxin PF05015.13 RUS78930.1 - 1.3 9.5 14.0 2.2 8.8 4.2 2.8 1 1 1 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB T3SS_needle_F PF09392.10 RUS78930.1 - 1.3 9.3 11.9 1.1 9.5 1.9 3.2 1 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Borealin PF10512.9 RUS78930.1 - 1.6 8.7 26.3 3.2 7.7 2.7 4.4 1 1 4 5 5 5 0 Cell division cycle-associated protein 8 OrfB_IS605 PF01385.19 RUS78930.1 - 1.9 8.7 26.7 3.4 7.9 8.6 2.2 1 1 1 2 2 2 0 Probable transposase IFP_35_N PF07334.13 RUS78930.1 - 2.8 8.1 20.1 1.6 8.9 1.0 4.2 1 1 3 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Latarcin PF10279.9 RUS78930.1 - 2.8 8.4 11.5 8.3 6.9 2.4 2.8 1 1 2 3 3 3 0 Latarcin precursor Rogdi_lz PF10259.9 RUS78930.1 - 3.3 7.1 20.5 1.7 8.0 4.3 2.1 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein FUSC PF04632.12 RUS78930.1 - 3.4 6.1 6.8 3.8 5.9 6.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4435 PF14491.6 RUS78930.1 - 3.9 7.3 15.8 7.6 6.4 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) DUF2203 PF09969.9 RUS78930.1 - 4.1 8.1 10.1 11 6.8 2.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Hsk3 PF08227.11 RUS78930.1 - 4.2 7.8 39.8 8.9 6.8 2.0 7.6 1 1 8 9 9 9 0 DASH complex subunit Hsk3 like HEPN PF05168.14 RUS78930.1 - 4.7 7.4 12.1 13 5.9 1.7 3.3 1 1 2 3 3 3 0 HEPN domain WbqC PF08889.11 RUS78930.1 - 5 7.0 7.8 16 5.3 0.6 2.0 1 1 1 2 2 2 0 WbqC-like protein family DUF3450 PF11932.8 RUS78930.1 - 5.7 6.2 11.2 7.4 5.8 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.18 RUS78930.1 - 9.2 5.5 8.3 11 5.2 8.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein XhlA PF10779.9 RUS78930.1 - 9.9 6.5 17.3 58 4.0 0.2 4.6 1 1 2 3 3 3 0 Haemolysin XhlA Galactosyl_T PF01762.21 RUS78931.1 - 2.4e-12 47.1 0.1 3.5e-11 43.3 0.1 2.0 1 1 0 1 1 1 1 Galactosyltransferase SPDY PF03771.16 RUS78932.1 - 0.1 12.6 0.1 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Arena_ncap_C PF17290.2 RUS78932.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Galactosyl_T PF01762.21 RUS78933.1 - 2.8e-34 118.6 0.1 3.3e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Galactosyltransferase DUF1647 PF07801.11 RUS78933.1 - 0.052 13.3 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Arena_ncap_C PF17290.2 RUS78934.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain SPDY PF03771.16 RUS78934.1 - 0.11 12.4 0.1 0.88 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Homeodomain PF00046.29 RUS78935.1 - 1.7e-21 75.8 4.8 1.7e-21 75.8 4.8 2.6 3 0 0 3 3 3 1 Homeodomain Acyl-CoA_dh_1 PF00441.24 RUS78937.1 - 5.4e-43 146.8 0.2 7.9e-43 146.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS78937.1 - 3.3e-26 91.3 0.1 1.2e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS78937.1 - 2e-09 38.1 0.1 0.001 19.7 0.0 2.7 1 1 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS78937.1 - 9.3e-09 35.7 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM_X2 PF03442.14 RUS78937.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 RRM_7 PF16367.5 RUS78939.1 - 3.5e-29 100.8 0.5 5e-27 93.9 0.3 3.4 2 1 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 RUS78939.1 - 4.8e-22 77.9 7.1 1.1e-21 76.8 6.5 2.0 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain CEBP1_N PF16368.5 RUS78939.1 - 3.5e-15 56.3 0.5 6.4e-15 55.5 0.5 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_1 PF00076.22 RUS78939.1 - 2.5e-08 33.6 0.0 0.0091 15.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 RUS78939.1 - 2.7 8.2 8.4 1.3 9.3 5.6 1.9 2 0 0 2 2 2 0 B-box zinc finger TFIIA PF03153.13 RUS78940.1 - 0.0095 16.0 18.6 0.01 15.9 18.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HGTP_anticodon2 PF12745.7 RUS78940.1 - 0.11 12.0 7.0 0.14 11.7 7.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CAC1F_C PF16885.5 RUS78940.1 - 0.21 11.2 13.3 0.24 11.0 13.3 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term ALMT PF11744.8 RUS78940.1 - 0.47 9.2 9.5 0.61 8.8 9.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 RUS78940.1 - 0.9 7.6 13.3 1 7.4 13.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 RUS78940.1 - 2 7.1 15.0 2.7 6.7 15.0 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 RUS78940.1 - 2.7 7.8 11.5 3.5 7.4 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PH PF00169.29 RUS78941.1 - 6.5e-24 84.5 0.0 1.3e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.21 RUS78941.1 - 6.9e-12 45.3 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.6 RUS78941.1 - 1.7e-05 25.1 0.2 0.007 16.8 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 RUS78941.1 - 0.014 15.7 0.1 16 5.9 0.0 3.2 2 2 0 2 2 2 0 Pleckstrin homology domain YAF2_RYBP PF17219.3 RUS78942.1 - 7.5e-16 57.4 0.3 1.8e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 RUS78942.1 - 3.3e-09 35.9 2.3 6.5e-09 35.0 2.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 RUS78942.1 - 0.0076 16.5 1.6 0.014 15.7 1.6 1.4 1 0 0 1 1 1 1 C1 domain zf-HIT PF04438.16 RUS78942.1 - 0.11 12.4 3.1 0.17 11.8 3.1 1.2 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.16 RUS78943.1 - 1.2e-30 106.7 30.5 2.4e-25 89.2 18.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 RUS78944.1 - 1e-168 561.6 0.8 1.2e-168 561.5 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_polI_A34 PF08208.11 RUS78945.1 - 5.9e-10 39.6 23.4 5.9e-10 39.6 23.4 3.1 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 RUS78945.1 - 9.2 6.2 28.1 0.16 11.9 4.8 3.5 3 1 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 Methyltransf_11 PF08241.12 RUS78946.1 - 7.8e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS78946.1 - 7.7e-11 42.6 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS78946.1 - 9.5e-11 41.7 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS78946.1 - 1.8e-10 40.9 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS78946.1 - 5e-09 36.8 0.0 7.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 RUS78946.1 - 0.00053 19.9 0.1 0.00095 19.1 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain DUF938 PF06080.12 RUS78946.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Rrf2 PF02082.20 RUS78946.1 - 0.019 15.3 0.1 0.039 14.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator MTS PF05175.14 RUS78946.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GhoS PF11080.8 RUS78946.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease GhoS LPMO_10 PF03067.15 RUS78947.1 - 4.7e-26 92.7 0.2 5.4e-26 92.5 0.2 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Fer4_4 PF12800.7 RUS78948.1 - 2 9.1 7.1 2e+02 2.9 7.1 2.3 1 1 0 1 1 1 0 4Fe-4S binding domain CBM_14 PF01607.24 RUS78949.1 - 0.00078 19.6 18.5 0.0025 17.9 8.3 3.8 2 2 2 4 4 4 3 Chitin binding Peritrophin-A domain MFS_1 PF07690.16 RUS78950.1 - 8.2e-33 113.8 33.6 4.1e-23 81.9 20.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 RUS78950.1 - 0.26 11.3 6.4 2.7 8.0 0.5 3.4 3 0 0 3 3 3 0 CoA-binding domain adh_short PF00106.25 RUS78951.1 - 2.1e-28 99.1 0.4 1.8e-27 96.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS78951.1 - 2.1e-15 57.0 0.0 1.1e-14 54.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS78951.1 - 4e-08 33.4 0.1 5.7e-08 32.9 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS78951.1 - 6.9e-05 22.4 0.0 9.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RUS78951.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding TUDOR PF00567.24 RUS78951.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Tudor domain Toprim PF01751.22 RUS78951.1 - 0.084 13.1 0.0 2.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Toprim domain SEFIR PF08357.11 RUS78952.1 - 0.00046 20.5 0.0 0.00072 19.8 0.0 1.3 1 0 0 1 1 1 1 SEFIR domain FMN_red PF03358.15 RUS78952.1 - 0.076 12.7 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Glyco_hydro_14 PF01373.17 RUS78952.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Pilin PF00114.19 RUS78953.1 - 2.7 8.9 7.8 0.85 10.6 0.3 2.3 1 1 1 2 2 2 0 Pilin (bacterial filament) Kinesin PF00225.23 RUS78956.1 - 2.8e-98 328.9 2.6 4.2e-98 328.3 2.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS78956.1 - 2.1e-46 157.6 0.3 3.5e-46 156.8 0.3 1.4 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 RUS78956.1 - 0.0006 20.1 0.5 0.0016 18.7 0.5 1.7 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1296 PF06972.11 RUS78956.1 - 0.0013 18.9 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) betaPIX_CC PF16523.5 RUS78956.1 - 0.011 15.5 5.1 0.026 14.3 5.1 1.6 1 0 0 1 1 1 0 betaPIX coiled coil SPATA1_C PF15743.5 RUS78956.1 - 0.011 15.8 6.4 0.022 14.8 6.4 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus CUE PF02845.16 RUS78956.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 CUE domain Macoilin PF09726.9 RUS78956.1 - 0.025 13.2 0.1 0.042 12.4 0.1 1.2 1 0 0 1 1 1 0 Macoilin family Caudo_TAP PF02413.17 RUS78956.1 - 0.046 13.9 0.3 0.13 12.4 0.3 1.8 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF5095 PF17016.5 RUS78956.1 - 0.1 12.3 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) zf-RRN7 PF11781.8 RUS78956.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Chordopox_G3 PF06129.12 RUS78956.1 - 0.14 12.9 0.3 0.32 11.7 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus G3 protein FlaC_arch PF05377.11 RUS78956.1 - 0.23 11.9 2.3 0.51 10.8 0.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 RUS78956.1 - 0.36 11.1 8.4 0.73 10.0 7.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Med21 PF11221.8 RUS78956.1 - 7 6.9 11.2 9.2 6.5 9.2 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex 7tm_1 PF00001.21 RUS78957.1 - 1.4e-25 90.1 5.7 2.4e-25 89.4 5.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS78957.1 - 4.7e-06 26.2 4.9 4.7e-06 26.2 4.9 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS78957.1 - 0.00096 19.0 3.7 0.0013 18.5 3.7 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS78957.1 - 0.016 14.9 8.0 0.026 14.1 8.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4658 PF15555.6 RUS78957.1 - 0.65 10.1 5.7 2 8.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Globin PF00042.22 RUS78958.1 - 8.3e-08 32.8 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Globin ACT_3 PF10000.9 RUS78958.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ACT domain Ras PF00071.22 RUS78959.1 - 5.2e-44 149.7 0.2 5.9e-31 107.2 0.0 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RUS78959.1 - 2.2e-19 69.8 0.5 4.5e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS78959.1 - 4.9e-08 32.6 0.0 0.00039 19.9 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family zf-Sec23_Sec24 PF04810.15 RUS78959.1 - 3e-06 27.2 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 RUS78959.1 - 1.1e-05 26.0 0.0 0.066 13.9 0.0 3.6 3 1 1 4 4 3 2 von Willebrand factor type A domain RsgA_GTPase PF03193.16 RUS78959.1 - 7.3e-05 22.7 0.1 0.0002 21.3 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase NMDAR2_C PF10565.9 RUS78959.1 - 0.00013 21.1 3.1 0.0015 17.5 0.0 2.6 3 0 0 3 3 3 1 N-methyl D-aspartate receptor 2B3 C-terminus Sec23_trunk PF04811.15 RUS78959.1 - 0.0012 18.4 0.2 0.026 14.1 0.2 2.4 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 RUS78959.1 - 0.013 16.2 0.2 0.12 13.1 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain GTP_EFTU PF00009.27 RUS78959.1 - 0.029 13.9 0.1 0.15 11.6 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Yippee-Mis18 PF03226.14 RUS78959.1 - 0.12 12.6 0.8 1 9.6 0.2 2.6 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRIMA1 PF16101.5 RUS78959.1 - 0.15 12.1 1.1 0.35 10.9 1.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 RUS78959.1 - 3.4 7.2 5.3 6.6 6.3 4.4 1.9 2 1 0 2 2 2 0 Virilizer, N-terminal Gal-bind_lectin PF00337.22 RUS78960.1 - 1.7e-16 60.0 1.3 2.1e-14 53.2 0.7 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin EF-hand_1 PF00036.32 RUS78961.1 - 1.1e-42 140.4 11.1 8.1e-10 37.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS78961.1 - 2.4e-35 120.8 3.2 1.3e-17 64.0 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS78961.1 - 1.3e-33 114.6 10.8 6.8e-16 57.9 0.8 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RUS78961.1 - 1.2e-30 102.8 6.2 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS78961.1 - 5.3e-28 95.2 9.0 6.9e-07 28.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS78961.1 - 1.9e-16 60.1 0.2 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS78961.1 - 5.6e-09 35.9 0.5 0.00057 19.8 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RUS78961.1 - 7.8e-08 32.6 0.1 0.009 16.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RUS78961.1 - 6.2e-06 27.0 0.0 0.0032 18.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 RUS78961.1 - 4.2e-05 23.5 0.0 0.043 13.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 RUS78961.1 - 8.3e-05 22.7 3.7 0.027 14.7 0.3 3.1 1 1 3 4 4 4 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 RUS78961.1 - 0.00032 20.7 0.8 0.0014 18.6 0.1 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 RUS78961.1 - 0.00049 20.1 0.7 0.077 12.9 0.7 3.5 1 1 0 1 1 1 1 Caleosin related protein TerB PF05099.13 RUS78961.1 - 0.0012 18.8 0.3 1.5 8.7 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 RUS78961.1 - 0.0013 19.5 0.2 0.73 10.6 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 RUS78961.1 - 0.003 17.2 0.8 0.0035 17.0 0.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.16 RUS78961.1 - 0.0034 17.7 0.5 1.6 9.1 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 SurA_N_2 PF13623.6 RUS78961.1 - 0.0058 16.5 0.7 0.43 10.4 0.1 2.4 1 1 1 2 2 2 1 SurA N-terminal domain DUF5580 PF17743.1 RUS78961.1 - 0.0068 15.0 0.0 0.0069 15.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 RUS78961.1 - 0.011 14.4 0.1 1.7 7.2 0.0 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF1296 PF06972.11 RUS78961.1 - 0.017 15.2 0.5 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) MotA_activ PF09114.10 RUS78961.1 - 0.023 14.8 0.3 0.46 10.6 0.0 2.4 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 RUS78961.1 - 0.029 13.6 0.0 1.9 7.6 0.0 2.1 1 1 0 2 2 2 0 Cache domain Poly_export PF02563.16 RUS78961.1 - 0.035 14.3 0.1 1.3 9.3 0.0 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 RUS78961.1 - 0.068 13.5 0.2 10 6.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 RUS78961.1 - 0.097 12.3 0.4 0.27 10.9 0.4 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Skp1 PF01466.19 RUS78961.1 - 0.5 10.5 4.4 20 5.4 0.1 3.2 3 0 0 3 3 3 0 Skp1 family, dimerisation domain EF-hand_1 PF00036.32 RUS78962.1 - 9.3e-43 140.6 10.6 3.2e-10 38.8 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS78962.1 - 2.4e-36 124.0 3.1 7.6e-19 67.9 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS78962.1 - 6.7e-33 112.3 10.9 5.4e-16 58.2 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RUS78962.1 - 4.3e-31 104.1 6.7 2.1e-09 36.5 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS78962.1 - 2.1e-27 93.3 8.2 1.1e-06 27.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS78962.1 - 1.5e-15 57.3 0.2 4.6e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS78962.1 - 1.3e-08 34.7 0.4 0.0027 17.6 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RUS78962.1 - 1.1e-07 32.1 0.0 0.0086 16.4 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RUS78962.1 - 3.8e-05 24.5 0.0 0.015 16.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 RUS78962.1 - 6.5e-05 22.9 0.0 0.071 13.1 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RUS78962.1 - 0.00041 20.4 0.7 0.0011 19.0 0.2 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 RUS78962.1 - 0.00093 18.9 1.5 0.0011 18.6 1.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 RUS78962.1 - 0.0022 18.7 0.2 3 8.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 RUS78962.1 - 0.0022 18.0 1.0 0.79 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 RUS78962.1 - 0.0035 17.3 1.2 1.2 9.1 0.0 2.5 1 1 2 3 3 3 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 RUS78962.1 - 0.0053 16.9 4.5 0.52 10.5 0.5 3.0 1 1 2 3 3 3 1 Dockerin type I domain DUF5580 PF17743.1 RUS78962.1 - 0.006 15.2 0.0 0.0065 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 RUS78962.1 - 0.0078 16.5 0.8 2.2 8.7 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 RUS78962.1 - 0.0078 16.7 0.0 3.7 8.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) dCache_2 PF08269.11 RUS78962.1 - 0.011 14.9 0.1 0.6 9.2 0.0 2.1 1 1 1 2 2 2 0 Cache domain SurA_N_2 PF13623.6 RUS78962.1 - 0.034 14.0 0.9 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 RUS78962.1 - 0.065 13.4 0.2 0.99 9.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF2267 PF10025.9 RUS78962.1 - 0.065 13.5 0.0 0.27 11.5 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Poly_export PF02563.16 RUS78962.1 - 0.085 13.1 0.0 1.3 9.3 0.0 2.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 RUS78962.1 - 0.14 12.6 0.1 17 5.8 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 RUS78962.1 - 0.2 11.3 0.6 0.47 10.1 0.6 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CLPTM1 PF05602.12 RUS78964.1 - 0.0059 15.7 2.4 0.0067 15.5 2.4 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) FOXP-CC PF16159.5 RUS78964.1 - 0.023 15.3 0.6 0.042 14.5 0.4 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 RUS78964.1 - 0.058 14.1 1.5 0.071 13.8 1.3 1.3 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Peptidase_C53 PF05550.11 RUS78964.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 CH PF00307.31 RUS78965.1 - 1.1e-24 86.7 0.0 2.5e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain NT-C2 PF10358.9 RUS78965.1 - 1.1e-19 70.5 0.1 3.1e-19 69.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3585 PF12130.8 RUS78965.1 - 4.6e-16 59.2 11.1 2.5e-15 56.8 8.2 2.5 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CAMSAP_CH PF11971.8 RUS78965.1 - 8.6e-07 28.7 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain TF_AP-2 PF03299.14 RUS78968.1 - 3.8e-81 271.8 0.0 4.4e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 M_domain PF12938.7 RUS78968.1 - 0.21 11.3 1.8 0.32 10.7 1.8 1.2 1 0 0 1 1 1 0 M domain of GW182 TFIIF_alpha PF05793.12 RUS78969.1 - 5.4e-112 375.1 73.5 6.2e-91 305.6 66.2 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ion_trans PF00520.31 RUS78969.1 - 0.24 10.6 2.0 0.37 10.0 2.0 1.2 1 0 0 1 1 1 0 Ion transport protein Antistasin PF02822.14 RUS78970.1 - 1.4e-38 131.1 94.9 8.2e-10 39.1 11.1 6.3 6 1 0 6 6 6 6 Antistasin family CFC PF09443.10 RUS78970.1 - 0.37 10.7 0.2 0.37 10.7 0.2 7.8 7 1 1 8 8 8 0 Cripto_Frl-1_Cryptic (CFC) Thioredoxin_7 PF13899.6 RUS78972.1 - 3.8e-16 59.1 0.0 8.9e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RUS78972.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 RUS78972.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 RUS78972.1 - 0.0002 21.4 0.4 0.00025 21.0 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 RUS78972.1 - 0.00038 20.9 0.0 0.00048 20.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS78972.1 - 0.071 13.4 0.0 0.67 10.3 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 RUS78973.1 - 3.6e-27 94.5 0.0 5.1e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 RUS78973.1 - 2.3e-08 33.9 0.1 1.8e-05 24.6 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 RUS78973.1 - 1.5e-07 31.4 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS78973.1 - 6.5e-05 22.7 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 RUS78973.1 - 0.00076 19.3 0.1 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin SCO1-SenC PF02630.14 RUS78973.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Thioredoxin_2 PF13098.6 RUS78973.1 - 0.023 15.1 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain GSHPx PF00255.19 RUS78974.1 - 1.3e-28 98.7 0.2 2.6e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione peroxidase Collectrin PF16959.5 RUS78974.1 - 0.056 13.2 0.2 0.091 12.5 0.2 1.2 1 0 0 1 1 1 0 Renal amino acid transporter MFS_5 PF05631.14 RUS78975.1 - 0.026 13.5 5.0 7.5 5.4 0.2 3.0 1 1 2 3 3 3 0 Sugar-tranasporters, 12 TM Med6 PF04934.14 RUS78975.1 - 0.17 11.6 0.1 68 3.3 0.0 3.1 2 1 1 3 3 3 0 MED6 mediator sub complex component C2-set_2 PF08205.12 RUS78977.1 - 0.0023 17.9 18.5 2.8 8.1 0.6 6.5 1 1 6 7 7 7 3 CD80-like C2-set immunoglobulin domain GILT PF03227.16 RUS78977.1 - 0.012 15.9 7.9 1.6 9.0 2.8 3.4 1 1 2 3 3 3 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Cas_Csm6 PF09659.10 RUS78977.1 - 0.023 13.5 1.4 2.2 6.9 2.1 2.9 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_Csm6) PsbW PF07123.12 RUS78977.1 - 0.45 10.5 3.7 14 5.7 0.6 3.3 1 1 3 4 4 4 0 Photosystem II reaction centre W protein (PsbW) MoaF PF10703.9 RUS78977.1 - 0.71 9.8 4.5 85 3.1 0.1 4.5 2 1 4 7 7 7 0 MoaF N-terminal domain Ig_mannosidase PF17753.1 RUS78977.1 - 1.7 8.4 3.5 68 3.3 0.0 3.3 2 1 0 3 3 3 0 Ig-fold domain DUF243 PF03103.17 RUS78977.1 - 2.9 8.3 8.0 15 6.0 2.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF243) His_binding PF02098.16 RUS78977.1 - 8.2 6.5 11.6 5.1 7.1 2.9 3.1 1 1 2 3 3 3 0 Tick histamine binding protein 7tm_1 PF00001.21 RUS78978.1 - 0.68 9.2 16.6 2.7 7.3 16.6 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Use1 PF09753.9 RUS78979.1 - 4e-70 236.3 3.6 4.5e-70 236.2 3.6 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Corona_S2 PF01601.16 RUS78979.1 - 0.014 13.9 0.4 0.21 10.0 0.1 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein GST_N_4 PF17172.4 RUS78979.1 - 0.082 13.7 0.3 13 6.6 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain IL31 PF15209.6 RUS78979.1 - 0.089 12.6 2.0 0.39 10.5 0.1 2.4 1 1 1 2 2 2 0 Interleukin 31 R3H PF01424.22 RUS78980.1 - 1.8e-07 31.0 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain Ank_4 PF13637.6 RUS78981.1 - 1.8e-17 63.4 0.1 7.6e-07 29.6 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS78981.1 - 3.3e-15 56.5 0.0 9.1e-08 32.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS78981.1 - 1.1e-12 47.9 0.1 1.6e-07 31.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS78981.1 - 2.5e-11 43.5 0.8 0.14 12.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 RUS78981.1 - 2.2e-10 39.8 0.3 0.0009 19.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat SOCS_box PF07525.16 RUS78981.1 - 1e-07 32.2 1.0 1.9e-07 31.3 1.0 1.5 1 0 0 1 1 1 1 SOCS box zf-C2H2_4 PF13894.6 RUS78982.1 - 2.1e-21 74.7 107.0 0.025 15.4 0.5 12.6 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS78982.1 - 7.2e-21 73.4 113.5 6e-05 23.3 0.5 12.6 12 0 0 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS78982.1 - 1.9e-06 28.0 88.5 0.004 17.4 0.1 11.9 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS78982.1 - 8.6e-05 22.8 1.1 8.6e-05 22.8 1.1 14.1 15 0 0 15 15 15 3 Zinc-finger double domain zf-met PF12874.7 RUS78982.1 - 0.00018 21.8 83.8 0.0067 16.8 0.5 11.6 12 0 0 12 12 12 5 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 RUS78982.1 - 0.011 15.6 1.4 0.058 13.2 0.2 5.9 6 1 0 6 6 6 0 C2H2 type zinc-finger (1 copy) DUF678 PF05077.12 RUS78982.1 - 0.025 14.7 6.8 8.7 6.6 0.1 5.4 4 0 0 4 4 4 0 Protein of unknown function (DUF678) GAGA PF09237.11 RUS78982.1 - 0.025 14.4 2.4 11 6.0 0.0 4.0 4 1 0 4 4 4 0 GAGA factor BolA PF01722.18 RUS78982.1 - 3.6 7.9 5.6 5.4 7.4 0.3 3.7 3 0 0 3 3 3 0 BolA-like protein ATP-synt_ab PF00006.25 RUS78983.1 - 7.6e-67 225.1 0.0 1.1e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RUS78983.1 - 3.3e-11 43.5 0.4 6.5e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF1664 PF07889.12 RUS78985.1 - 0.29 11.2 3.4 2.7 8.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 RUS78985.1 - 0.33 10.1 4.7 0.38 9.9 1.1 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF745 PF05335.13 RUS78985.1 - 0.47 10.2 7.3 0.79 9.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Hrs_helical PF12210.8 RUS78985.1 - 2.3 8.8 6.7 1.2 9.7 1.3 2.6 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF948 PF06103.11 RUS78985.1 - 6.3 7.1 7.1 7 7.0 2.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Drf_GBD PF06371.13 RUS78986.1 - 1.7e-05 24.5 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain SNAPc19 PF15497.6 RUS78987.1 - 2.5e-12 47.1 14.3 1.6e-11 44.5 14.3 2.1 1 1 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Methyltransf_14 PF08484.11 RUS78987.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain NUT PF12881.7 RUS78987.1 - 0.46 8.8 4.2 0.65 8.4 4.2 1.2 1 0 0 1 1 1 0 NUT protein NOA36 PF06524.12 RUS78987.1 - 1.1 8.6 5.2 1.3 8.3 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein PBP_sp32 PF07222.12 RUS78987.1 - 1.3 8.4 4.5 1.9 7.9 4.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.10 RUS78987.1 - 1.3 9.4 9.8 2.1 8.8 9.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IL5 PF02025.15 RUS78989.1 - 0.037 14.3 2.3 33 4.8 0.0 4.0 2 1 1 4 4 4 0 Interleukin 5 Halogen_Hydrol PF10112.9 RUS78989.1 - 5.1 7.1 7.1 49 3.9 0.0 4.6 1 1 3 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4588 PF15251.6 RUS78990.1 - 1.6e-06 28.1 0.6 2e-06 27.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Cadherin PF00028.17 RUS78992.1 - 0.0062 17.0 0.1 0.021 15.3 0.1 2.0 1 0 0 1 1 1 1 Cadherin domain WD40 PF00400.32 RUS78994.1 - 5.4e-06 27.0 0.0 0.21 12.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RUS78994.1 - 0.024 13.6 0.0 0.42 9.5 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RUS78994.1 - 0.031 14.6 0.0 1 9.7 0.0 3.2 2 1 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Gasdermin_C PF17708.1 RUS78995.1 - 3.3e-05 24.1 0.1 1.7 8.7 0.0 3.5 1 1 3 4 4 4 3 Gasdermin PUB domain EAGR_box PF16713.5 RUS78995.1 - 0.00025 20.6 8.9 91 2.8 0.0 8.2 10 0 0 10 10 10 0 Enriched in aromatic and glycine Residues box Histone_H2A_C PF16211.5 RUS78995.1 - 0.0011 18.6 6.8 3.3e+02 1.1 0.0 8.5 10 0 0 10 10 10 0 C-terminus of histone H2A DUF3802 PF12290.8 RUS78995.1 - 0.0039 17.7 32.2 14 6.3 0.1 9.2 1 1 10 11 11 11 4 Protein of unknown function (DUF3802) DUF2770 PF10968.8 RUS78995.1 - 0.006 16.5 41.1 24 5.0 0.2 10.1 10 0 0 10 10 10 2 Protein of unknown function (DUF2770) zf-C3HC4_4 PF15227.6 RUS78995.1 - 0.032 14.4 28.4 16 5.7 0.6 6.6 1 1 7 9 9 9 0 zinc finger of C3HC4-type, RING FAM47 PF14642.6 RUS78996.1 - 0.0001 22.0 24.6 0.043 13.4 4.7 3.8 1 1 2 4 4 4 4 FAM47 family PPARgamma_N PF12577.8 RUS78996.1 - 0.49 11.1 3.3 27 5.5 0.1 3.5 1 1 2 3 3 3 0 PPAR gamma N-terminal region CUE PF02845.16 RUS78997.1 - 0.0012 18.5 2.3 37 4.2 0.0 5.6 4 1 3 7 7 7 5 CUE domain HECT PF00632.25 RUS78998.1 - 3.7e-82 276.2 1.1 3.7e-82 276.2 1.1 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 RUS78998.1 - 3.8e-62 206.7 29.1 4.6e-12 46.4 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS78998.1 - 1.2e-33 114.2 35.5 1.1e-08 34.7 2.9 8.3 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 RUS78999.1 - 1e-09 38.1 6.3 7.5e-05 22.5 2.3 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 RUS78999.1 - 0.0001 22.1 5.3 0.29 11.1 0.0 3.5 3 0 0 3 3 3 2 F-box domain E1_dh PF00676.20 RUS79000.1 - 1.4e-75 254.0 0.0 2.3e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 RUS79000.1 - 5.3e-50 169.1 0.0 3e-49 166.6 0.0 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 RUS79000.1 - 1.1e-48 165.3 0.0 3.2e-48 163.8 0.0 1.8 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain 2-oxogl_dehyd_N PF16078.5 RUS79000.1 - 1.3e-19 69.4 1.8 2.7e-19 68.5 0.7 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Transket_pyr PF02779.24 RUS79001.1 - 4.6e-06 26.4 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain zf-C2HE PF16278.5 RUS79002.1 - 0.13 12.7 0.8 0.33 11.5 0.8 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 RUS79002.1 - 0.49 10.9 3.2 12 6.5 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double domain NAD_kinase PF01513.21 RUS79007.1 - 1.2e-05 24.7 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RUS79007.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HALZ PF02183.18 RUS79008.1 - 2.1e-06 27.9 0.6 0.5 10.6 0.1 4.3 1 1 5 6 6 6 2 Homeobox associated leucine zipper DUF874 PF05917.11 RUS79008.1 - 0.00018 20.7 6.6 0.092 11.8 0.5 2.3 1 1 1 2 2 2 2 Helicobacter pylori protein of unknown function (DUF874) Spc7 PF08317.11 RUS79008.1 - 0.001 18.0 12.0 0.0095 14.8 8.1 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 RUS79008.1 - 0.002 17.7 11.7 0.0078 15.8 11.7 1.9 1 1 0 1 1 1 1 Exonuclease VII, large subunit Nre_C PF04895.12 RUS79008.1 - 0.011 15.6 2.6 6.4 6.8 0.1 3.3 1 1 2 3 3 3 0 Archaeal Nre, C-terminal bZIP_1 PF00170.21 RUS79008.1 - 0.016 15.3 5.4 1.1 9.5 0.4 3.3 1 1 3 4 4 4 0 bZIP transcription factor DUF3053 PF11254.8 RUS79008.1 - 0.018 14.6 3.4 2.8 7.5 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) SHE3 PF17078.5 RUS79008.1 - 0.026 14.3 3.4 4.1 7.1 2.5 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 IFT57 PF10498.9 RUS79008.1 - 0.031 13.2 13.2 0.015 14.3 7.2 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 RUS79008.1 - 0.088 12.9 9.4 0.51 10.4 9.3 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RUS79008.1 - 0.098 12.7 10.9 3.4 7.7 10.6 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0449 PF15136.6 RUS79008.1 - 0.13 12.8 16.7 91 3.6 6.0 4.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 ADIP PF11559.8 RUS79008.1 - 0.14 12.2 16.8 2.2 8.3 0.9 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 RUS79008.1 - 0.15 11.9 10.1 0.71 9.7 2.2 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.9 RUS79008.1 - 0.17 10.7 16.0 0.81 8.5 9.0 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain KASH_CCD PF14662.6 RUS79008.1 - 0.27 11.0 11.3 0.99 9.2 11.3 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KELK PF15796.5 RUS79008.1 - 0.33 11.4 15.2 3.3 8.2 7.8 3.2 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4200 PF13863.6 RUS79008.1 - 0.33 11.3 6.8 1.3 9.5 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Rogdi_lz PF10259.9 RUS79008.1 - 0.4 10.1 19.5 7.4e+02 -0.6 19.4 3.1 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein DUF812 PF05667.11 RUS79008.1 - 0.42 9.4 13.2 1.1 8.0 13.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3552 PF12072.8 RUS79008.1 - 0.49 9.8 15.4 1.1 8.6 7.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) COG5 PF10392.9 RUS79008.1 - 0.7 10.1 11.3 2.7 8.2 1.6 3.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 EzrA PF06160.12 RUS79008.1 - 0.92 7.6 6.0 3.5 5.7 6.0 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 RUS79008.1 - 0.99 7.2 4.7 1.7 6.4 4.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.8 RUS79008.1 - 1 6.8 11.9 1.5 6.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 RUS79008.1 - 1.1 9.8 8.5 2.7 8.5 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 JIP_LZII PF16471.5 RUS79008.1 - 1.1 9.4 3.4 32 4.8 0.1 2.7 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II FPP PF05911.11 RUS79008.1 - 1.3 7.1 15.3 1.7 6.7 15.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil PspA_IM30 PF04012.12 RUS79008.1 - 1.6 8.3 8.3 7.7 6.0 4.1 2.7 1 1 1 2 2 2 0 PspA/IM30 family GAS PF13851.6 RUS79008.1 - 1.6 8.0 16.5 3.9 6.8 9.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RasGAP_C PF03836.15 RUS79008.1 - 1.9 8.6 9.9 4.8 7.3 5.5 2.5 1 1 1 2 2 2 0 RasGAP C-terminus EMP24_GP25L PF01105.24 RUS79008.1 - 4.9 7.0 5.1 2.2 8.2 0.5 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD PI3K_P85_iSH2 PF16454.5 RUS79008.1 - 5.5 6.6 16.2 27 4.3 15.4 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Myc-LZ PF02344.15 RUS79008.1 - 6.6 6.9 33.9 13 6.0 3.4 7.1 1 1 6 7 7 7 0 Myc leucine zipper domain Tropomyosin_1 PF12718.7 RUS79008.1 - 10 6.3 14.1 25 5.0 14.1 1.7 1 0 0 1 1 1 0 Tropomyosin like LRR_adjacent PF08191.11 RUS79009.1 - 6.6 7.0 6.5 45 4.4 0.1 4.0 2 1 3 5 5 5 0 LRR adjacent Sulfotransfer_1 PF00685.27 RUS79010.1 - 2.3e-18 66.7 0.0 3.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS79010.1 - 1.2e-12 48.7 0.3 5.4e-09 36.7 0.2 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS79010.1 - 0.0023 17.9 0.2 0.004 17.1 0.2 1.4 1 0 0 1 1 1 1 Sulfotransferase family CCT_2 PF09425.10 RUS79011.1 - 2.1e-05 24.3 49.6 15 5.6 0.2 11.6 12 0 0 12 12 12 9 Divergent CCT motif YL1 PF05764.13 RUS79011.1 - 0.0087 16.2 42.6 4.1e+02 0.9 42.6 2.6 1 1 0 1 1 1 0 YL1 nuclear protein ARTD15_N PF18084.1 RUS79011.1 - 0.033 14.4 18.6 23 5.3 0.9 8.4 1 1 6 7 7 7 0 ARTD15 N-terminal domain LepB_N PF18640.1 RUS79011.1 - 0.047 13.3 0.0 73 2.9 0.0 3.4 1 1 5 7 7 7 0 LepB N-terminal domain NOA36 PF06524.12 RUS79011.1 - 0.22 10.8 15.5 0.36 10.1 15.5 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS79011.1 - 2.2 6.3 13.7 2.9 5.9 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Forkhead PF00250.18 RUS79013.1 - 2.3e-37 127.1 0.1 3.4e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 RUS79013.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family Pep_M12B_propep PF01562.19 RUS79014.1 - 4.5e-09 36.7 0.1 1.6e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide AF-4 PF05110.13 RUS79014.1 - 0.088 10.9 12.4 0.11 10.5 12.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SDA1 PF05285.12 RUS79014.1 - 1.9 7.8 15.4 2.7 7.4 15.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS79014.1 - 3 5.9 13.7 3.8 5.6 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3134 PF11332.8 RUS79014.1 - 6.2 7.2 14.1 8.6 6.8 2.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3134) Glyco_transf_92 PF01697.27 RUS79015.1 - 5.1e-23 82.0 0.1 9.3e-23 81.2 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS79015.1 - 0.0098 16.4 0.0 0.057 13.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 RTTN_N PF14726.6 RUS79015.1 - 0.16 12.8 0.0 0.37 11.6 0.0 1.5 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DUF3446 PF11928.8 RUS79016.1 - 0.18 12.1 14.8 0.16 12.3 13.1 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4950 PF16308.5 RUS79016.1 - 0.36 10.8 7.7 0.43 10.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) SR-25 PF10500.9 RUS79016.1 - 0.38 10.3 23.7 0.46 10.0 23.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RFX5_DNA_bdg PF14621.6 RUS79016.1 - 1.4 8.7 8.4 1.8 8.3 8.4 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain SSP160 PF06933.11 RUS79016.1 - 1.5 6.9 14.4 1.7 6.8 14.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 RUS79016.1 - 7.4 5.0 8.1 8.5 4.8 8.1 1.0 1 0 0 1 1 1 0 Macoilin family ABC_tran PF00005.27 RUS79017.1 - 7.3e-31 107.5 1.4 3.3e-19 69.8 0.0 3.6 3 1 1 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 RUS79017.1 - 1.5e-23 82.7 3.2 1.5e-23 82.7 3.2 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 RUS79017.1 - 1.5e-10 41.4 4.6 0.009 15.9 0.1 3.7 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS79017.1 - 1.7e-05 24.5 0.1 0.046 13.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 RUS79017.1 - 3.5e-05 23.6 0.1 0.14 11.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 RUS79017.1 - 4.7e-05 23.7 0.2 0.41 10.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 RUS79017.1 - 5.5e-05 23.1 0.3 0.16 11.9 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 RUS79017.1 - 6.9e-05 23.4 4.4 0.16 12.5 0.0 4.2 4 1 0 4 4 4 2 AAA domain NACHT PF05729.12 RUS79017.1 - 7e-05 22.8 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 RUS79017.1 - 0.00031 21.0 2.1 0.26 11.6 0.0 3.3 4 1 0 4 4 2 2 AAA domain AAA_16 PF13191.6 RUS79017.1 - 0.00032 21.1 0.1 0.4 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 RUS79017.1 - 0.00034 20.5 9.1 0.09 12.5 0.2 3.5 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 RUS79017.1 - 0.00059 19.9 2.1 0.26 11.4 0.0 3.7 4 1 0 4 4 4 1 50S ribosome-binding GTPase MobB PF03205.14 RUS79017.1 - 0.00061 19.7 0.1 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 RUS79017.1 - 0.0012 19.3 0.2 2.9 8.3 0.0 3.3 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RUS79017.1 - 0.0015 18.1 3.5 0.88 9.1 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 RUS79017.1 - 0.0019 18.2 0.3 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 RUS79017.1 - 0.0022 17.5 0.2 2.3 7.6 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Roc PF08477.13 RUS79017.1 - 0.0031 17.7 0.0 0.19 11.9 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 RUS79017.1 - 0.0058 17.1 0.0 0.0058 17.1 0.0 4.9 4 1 1 6 6 4 2 AAA domain Arf PF00025.21 RUS79017.1 - 0.0064 16.0 1.4 0.23 10.9 0.0 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_14 PF13173.6 RUS79017.1 - 0.0066 16.5 0.2 2.9 8.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 RUS79017.1 - 0.0067 16.3 0.1 5.5 6.9 0.0 2.9 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 RUS79017.1 - 0.007 15.5 0.2 0.11 11.5 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein NB-ARC PF00931.22 RUS79017.1 - 0.0072 15.5 2.7 4.8 6.3 0.0 3.7 4 0 0 4 4 4 1 NB-ARC domain PduV-EutP PF10662.9 RUS79017.1 - 0.012 15.4 1.7 2.4 7.9 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RUS79017.1 - 0.018 15.1 1.6 1.6 8.7 0.0 3.8 4 0 0 4 4 4 0 Dynamin family RNA_helicase PF00910.22 RUS79017.1 - 0.019 15.4 0.0 3.9 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 RUS79017.1 - 0.02 14.4 0.8 3.2 7.2 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 RUS79017.1 - 0.022 14.4 0.0 7.3 6.2 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 RUS79017.1 - 0.035 14.3 0.5 7 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 RUS79017.1 - 0.037 13.8 0.0 4.3 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 RUS79017.1 - 0.056 12.4 0.0 11 4.9 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dNK PF01712.19 RUS79017.1 - 0.37 10.6 5.7 2.3 8.0 0.0 3.6 4 0 0 4 4 4 0 Deoxynucleoside kinase DUF87 PF01935.17 RUS79017.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.7 3 1 1 4 4 4 0 Helicase HerA, central domain DUF1672 PF07901.11 RUS79017.1 - 1.6 8.0 9.8 0.039 13.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) Glyco_hydro_18 PF00704.28 RUS79021.1 - 0.00071 19.4 0.0 0.00094 19.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NIF PF03031.18 RUS79022.1 - 1.3e-50 171.2 0.0 1.6e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 RUS79022.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PMP22_Claudin PF00822.20 RUS79023.1 - 6.8e-11 42.3 1.0 7.8e-11 42.1 1.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS79023.1 - 1.8e-07 31.1 8.8 7.5e-06 25.8 8.8 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS79023.1 - 0.075 13.0 2.4 0.29 11.1 2.4 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF2207 PF09972.9 RUS79023.1 - 1.1 7.9 4.7 3.4 6.3 2.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ERG2_Sigma1R PF04622.12 RUS79024.1 - 9.4e-69 230.9 1.4 1.2e-68 230.6 1.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein VPS9 PF02204.18 RUS79026.1 - 1e-20 73.9 0.4 3.8e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain SH2 PF00017.24 RUS79026.1 - 8.5e-08 32.2 0.0 2.2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 RUS79026.1 - 1.6e-07 31.8 0.7 4.1e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FERM_f0 PF16511.5 RUS79026.1 - 0.0026 18.0 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Codanin-1_C PF15296.6 RUS79027.1 - 0.028 14.5 1.7 0.12 12.4 0.3 2.9 2 0 0 2 2 2 0 Codanin-1 C-terminus CAP PF00188.26 RUS79028.1 - 6.7e-23 81.9 6.7 7.5e-12 46.2 1.7 2.5 2 0 0 2 2 2 2 Cysteine-rich secretory protein family PGBA_C PF15437.6 RUS79028.1 - 0.93 9.9 45.1 0.055 13.8 26.5 3.4 1 1 2 3 3 3 0 Plasminogen-binding protein pgbA C-terminal 7tm_1 PF00001.21 RUS79029.1 - 3.6e-58 196.9 23.3 3.6e-58 196.9 23.3 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS79029.1 - 9.3e-14 51.4 21.8 1.4e-13 50.8 21.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS79029.1 - 2.1e-09 37.1 19.2 2.1e-09 37.1 19.2 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS79029.1 - 8.6e-09 35.4 21.5 1.5e-08 34.6 21.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS79029.1 - 2.5e-06 27.0 23.4 1.3e-05 24.6 22.6 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS79030.1 - 2.8e-59 200.6 22.0 2.8e-59 200.6 22.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS79030.1 - 6.4e-16 58.5 21.8 8.5e-16 58.1 21.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS79030.1 - 1.2e-12 47.8 13.8 1.2e-12 47.8 13.8 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS79030.1 - 3.2e-10 40.1 13.0 3.2e-10 40.1 13.0 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS79030.1 - 5.7e-07 29.1 19.3 2.4e-06 27.1 18.6 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS79030.1 - 3.2e-05 23.8 17.4 4.6e-05 23.3 17.4 1.1 1 0 0 1 1 1 1 Olfactory receptor DUF1772 PF08592.11 RUS79030.1 - 0.81 10.0 5.5 88 3.4 6.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DOMON PF03351.17 RUS79031.1 - 6.7e-07 29.6 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 DOMON domain ADK PF00406.22 RUS79032.1 - 4.1e-48 163.3 0.0 4.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RUS79032.1 - 8e-22 78.1 0.0 2.5e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 RUS79032.1 - 7.5e-17 61.0 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 RUS79032.1 - 1e-05 26.1 0.0 2.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS79032.1 - 0.0016 18.7 0.5 0.0026 17.9 0.1 1.8 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 RUS79032.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Ploopntkinase3 PF18751.1 RUS79032.1 - 0.18 11.7 0.0 0.63 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CFC PF09443.10 RUS79033.1 - 2.9e-10 39.8 8.9 2.9e-10 39.8 8.9 2.2 2 0 0 2 2 2 1 Cripto_Frl-1_Cryptic (CFC) Lipase PF00151.19 RUS79034.1 - 4.8e-69 233.2 0.0 6.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS79034.1 - 0.0042 17.7 0.2 0.0056 17.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS79034.1 - 0.051 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 RUS79034.1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain YTH PF04146.15 RUS79035.1 - 1.9e-40 138.5 0.2 1.9e-40 138.5 0.2 3.9 2 2 0 2 2 2 1 YT521-B-like domain GREB1 PF15782.5 RUS79035.1 - 9 3.3 17.3 13 2.7 17.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DNA_primase_lrg PF04104.14 RUS79036.1 - 8.8e-85 284.3 0.0 1.4e-84 283.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF1232 PF06803.12 RUS79037.1 - 1.3e-08 34.5 13.0 1.3e-08 34.5 13.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4 PF00097.25 RUS79037.1 - 2.3e-07 30.5 5.1 3.7e-07 29.9 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79037.1 - 5.7e-07 29.3 3.5 8.1e-07 28.8 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS79037.1 - 6e-07 29.7 7.9 1e-06 29.0 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS79037.1 - 1.2e-06 28.2 7.0 2.4e-06 27.3 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS79037.1 - 4.5e-06 26.6 4.7 7.6e-06 25.9 4.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS79037.1 - 6.8e-06 26.1 4.5 1.5e-05 25.0 4.6 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS79037.1 - 0.00021 21.1 8.3 0.0039 17.0 9.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Tmemb_55A PF09788.9 RUS79037.1 - 0.0077 15.4 2.3 0.014 14.5 2.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 55A zf-RING_5 PF14634.6 RUS79037.1 - 0.011 15.7 10.4 0.25 11.3 11.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 RUS79037.1 - 0.02 14.8 2.9 0.04 13.9 2.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) HypA PF01155.19 RUS79037.1 - 0.056 13.5 2.3 0.14 12.2 2.3 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA VD10_N PF08476.10 RUS79037.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral D10 N-terminal DZR PF12773.7 RUS79037.1 - 0.079 13.0 4.8 0.29 11.2 4.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 RUS79037.1 - 0.081 13.0 5.3 0.15 12.1 5.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 RUS79037.1 - 0.11 12.3 6.0 0.051 13.4 2.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.12 RUS79037.1 - 0.78 9.3 3.1 2 8.0 1.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding TerY_C PF15616.6 RUS79037.1 - 0.82 9.8 6.6 4.8 7.3 6.6 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain zf-Di19 PF05605.12 RUS79037.1 - 1.1 9.6 5.8 42 4.5 3.0 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Lar_restr_allev PF14354.6 RUS79037.1 - 2.3 8.7 8.0 25 5.4 8.0 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C6H2 PF15801.5 RUS79037.1 - 3.2 8.1 9.2 0.49 10.7 3.3 2.2 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding FYVE PF01363.21 RUS79037.1 - 4.3 7.5 9.0 2.5e+02 1.9 9.0 2.5 1 1 0 1 1 1 0 FYVE zinc finger AKAP7_NLS PF10469.9 RUS79038.1 - 1.6e-37 129.5 0.0 3e-37 128.6 0.0 1.5 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 RUS79038.1 - 2e-07 31.1 0.0 8.4e-07 29.0 0.0 1.8 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily CPDase PF07823.11 RUS79038.1 - 0.0061 16.3 0.1 0.073 12.8 0.0 2.2 2 0 0 2 2 2 1 Cyclic phosphodiesterase-like protein BEX PF04538.12 RUS79038.1 - 0.051 14.2 3.4 2 9.0 1.9 2.3 2 0 0 2 2 2 0 Brain expressed X-linked like family ABC2_membrane PF01061.24 RUS79039.1 - 0.066 12.6 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter RRN3 PF05327.11 RUS79040.1 - 0.035 12.7 8.3 0.038 12.5 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 RUS79040.1 - 0.052 12.7 24.5 0.062 12.4 24.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS79040.1 - 0.084 11.1 10.9 0.1 10.8 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS79040.1 - 0.41 10.0 14.5 0.5 9.8 14.5 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 RUS79040.1 - 0.53 9.4 3.4 0.67 9.1 3.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 RUS79040.1 - 0.68 9.2 8.2 0.77 9.0 8.2 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 RUS79040.1 - 1 9.1 5.6 1.4 8.7 5.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIA PF03153.13 RUS79040.1 - 1.4 8.9 23.7 1.7 8.6 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pes-10 PF07149.11 RUS79040.1 - 6.6 5.7 9.3 9.6 5.1 9.3 1.3 1 0 0 1 1 1 0 Pes-10 MAM PF00629.23 RUS79042.1 - 4.5e-06 26.7 0.0 5.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Y_phosphatase PF00102.27 RUS79043.1 - 1.6e-24 86.8 0.0 6.2e-24 84.9 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DNA_pol_phi PF04931.13 RUS79043.1 - 0.0013 16.9 30.0 0.0013 16.9 30.0 1.4 2 0 0 2 2 2 1 DNA polymerase phi DUF4637 PF15470.6 RUS79043.1 - 0.013 15.2 1.3 0.013 15.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) FBP_C PF16571.5 RUS79043.1 - 0.15 11.6 0.2 0.31 10.5 0.2 1.5 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger PPP4R2 PF09184.11 RUS79043.1 - 2.6 7.5 25.7 0.32 10.6 21.4 1.6 2 0 0 2 2 2 0 PPP4R2 SGT1 PF07093.11 RUS79043.1 - 4 5.7 11.7 6.4 5.1 11.7 1.3 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.15 RUS79043.1 - 4.2 6.0 7.8 7.3 5.2 7.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS79043.1 - 4.3 5.4 27.4 0.035 12.3 19.3 1.5 2 0 0 2 2 2 0 Nop14-like family TRAP_alpha PF03896.16 RUS79043.1 - 5.3 6.2 13.2 0.9 8.7 9.3 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Rhabdo_ncap PF00945.18 RUS79043.1 - 8.6 5.1 9.5 15 4.3 9.5 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Y_phosphatase PF00102.27 RUS79044.1 - 2.4e-24 86.2 0.0 2.9e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS79044.1 - 4.2e-06 26.9 0.0 4.2e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RUS79044.1 - 1.4e-05 24.9 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS79044.1 - 3e-05 24.2 0.0 3.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 RUS79044.1 - 0.096 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3725 PF12523.8 RUS79044.1 - 0.14 12.4 0.1 0.3 11.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3725) Y_phosphatase2 PF03162.13 RUS79044.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Prenyltrans PF00432.21 RUS79044.1 - 0.46 10.3 1.8 0.84 9.4 0.2 2.1 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat DUF202 PF02656.15 RUS79045.1 - 4.1e-05 23.9 3.1 70 4.0 0.0 5.3 5 0 0 5 5 5 5 Domain of unknown function (DUF202) F5_F8_type_C PF00754.25 RUS79046.1 - 0.0015 18.7 0.1 0.004 17.3 0.1 1.8 1 1 1 2 2 2 1 F5/8 type C domain Y_phosphatase PF00102.27 RUS79047.1 - 6.6e-30 104.4 0.0 8.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 RUS79048.1 - 3.3e-66 223.2 0.1 4.7e-66 222.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS79048.1 - 0.00021 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RUS79048.1 - 0.00053 20.1 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 RUS79048.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SKG6 PF08693.10 RUS79048.1 - 0.04 13.3 5.0 0.079 12.4 5.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F5_F8_type_C PF00754.25 RUS79048.1 - 0.068 13.3 0.2 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 F5/8 type C domain Y_phosphatase PF00102.27 RUS79049.1 - 1.9e-102 341.8 0.0 1.2e-70 237.7 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS79049.1 - 0.00025 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RUS79049.1 - 0.00041 20.2 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS79049.1 - 0.0013 18.9 0.0 0.0053 16.9 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Zn_Tnp_IS1 PF03811.13 RUS79049.1 - 0.12 12.1 0.1 0.5 10.1 0.0 2.1 1 1 1 2 2 2 0 InsA N-terminal domain DNA_ligase_ZBD PF03119.16 RUS79050.1 - 0.0003 20.7 9.0 1.4e+02 2.6 0.1 10.4 4 3 2 6 6 6 0 NAD-dependent DNA ligase C4 zinc finger domain Colipase-like PF15083.6 RUS79050.1 - 0.00043 20.3 0.5 0.31 11.2 0.0 3.0 2 1 0 2 2 2 2 Colipase-like DUF905 PF06006.12 RUS79050.1 - 0.017 15.1 13.9 65 3.6 0.0 9.2 2 1 11 15 15 15 0 Bacterial protein of unknown function (DUF905) ASC PF00858.24 RUS79051.1 - 0.003 16.6 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS79052.1 - 0.0024 16.9 0.5 0.0031 16.6 0.5 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel PAP2 PF01569.21 RUS79052.1 - 0.0079 16.0 0.0 0.0088 15.8 0.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily PMT2_N PF17987.1 RUS79053.1 - 2.7e-05 24.4 1.7 6.3 7.0 0.1 4.0 1 1 3 4 4 4 2 Phosphoethanolamine N-methyltransferase 2 N-terminal UPF0051 PF01458.17 RUS79053.1 - 0.0011 18.7 0.6 0.005 16.6 0.6 1.8 1 1 0 1 1 1 1 Uncharacterized protein family (UPF0051) MG1 PF17790.1 RUS79053.1 - 0.2 12.1 9.6 2.8e+02 2.0 9.6 2.9 1 1 0 1 1 1 0 Macroglobulin domain MG1 PPC PF04151.15 RUS79053.1 - 0.23 12.6 10.2 6.8 7.9 4.4 2.8 1 1 1 2 2 2 0 Bacterial pre-peptidase C-terminal domain Stap_Strp_tox_C PF02876.17 RUS79053.1 - 0.23 11.8 21.0 14 6.0 7.3 3.7 1 1 2 3 3 3 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Exonuc_VII_L PF02601.15 RUS79053.1 - 2.2 7.8 8.8 2.5 7.6 8.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 RUS79053.1 - 4.5 6.6 9.9 12 5.3 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CBM_14 PF01607.24 RUS79054.1 - 5.2e-10 39.3 4.8 7.4e-10 38.8 4.8 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain ESSS PF10183.9 RUS79054.1 - 0.22 11.7 0.0 0.29 11.4 0.0 1.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_18 PF00704.28 RUS79055.1 - 6.8e-72 242.8 0.1 1.8e-69 234.8 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 RUS79056.1 - 3.2e-24 85.5 2.6 3.9e-24 85.2 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS79056.1 - 6.5e-09 35.1 0.4 7.6e-09 34.9 0.2 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 RUS79056.1 - 0.008 15.1 0.4 0.014 14.3 0.4 1.4 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RUS79057.1 - 8.4e-13 48.0 11.2 3.3e-10 39.4 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 RUS79057.1 - 0.0048 16.8 3.6 0.007 16.3 3.6 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling adh_short PF00106.25 RUS79058.1 - 6.4e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase BCA_ABC_TP_C PF12399.8 RUS79058.1 - 1.4 8.9 3.9 0.34 10.9 0.3 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter GBP_PSP PF02425.15 RUS79058.1 - 8.1 6.2 6.1 1.9 8.2 0.3 2.5 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Gal-3-0_sulfotr PF06990.11 RUS79059.1 - 9.2e-52 176.3 0.1 1.3e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS79059.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family DUF1685 PF07939.11 RUS79059.1 - 0.13 12.0 0.2 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) Methyltransf_PK PF05891.12 RUS79061.1 - 0.00012 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 RUS79061.1 - 0.00069 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 RUS79061.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RUS79061.1 - 0.062 14.0 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 RUS79061.1 - 0.072 13.1 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zinc_ribbon_10 PF10058.9 RUS79063.1 - 2.5e-15 55.9 0.0 4.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein 7tm_6 PF02949.20 RUS79063.1 - 0.023 13.8 0.3 0.038 13.1 0.3 1.2 1 0 0 1 1 1 0 7tm Odorant receptor 2TM PF13239.6 RUS79063.1 - 0.045 14.1 1.5 0.074 13.4 1.5 1.3 1 0 0 1 1 1 0 2TM domain Orf78 PF06024.12 RUS79063.1 - 2.6 8.4 4.4 0.79 10.1 0.2 2.3 2 0 0 2 2 2 0 Orf78 (ac78) PDEase_I PF00233.19 RUS79064.1 - 3.6e-35 121.8 0.0 4.4e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FH2 PF02181.23 RUS79066.1 - 6.5e-71 239.4 0.6 1.1e-70 238.7 0.6 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Fes1 PF08609.10 RUS79066.1 - 0.18 12.7 1.1 0.8 10.6 0.8 2.3 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Halogen_Hydrol PF10112.9 RUS79066.1 - 0.71 9.9 3.6 2.1 8.4 0.1 2.8 4 0 0 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Lectin_C PF00059.21 RUS79067.1 - 1.1e-10 42.2 5.3 2.9e-10 40.8 5.3 1.7 1 0 0 1 1 1 1 Lectin C-type domain Baculo_11_kDa PF06143.11 RUS79067.1 - 0.022 14.3 1.2 0.045 13.3 1.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family MPS-4 PF17523.2 RUS79067.1 - 0.15 12.2 1.4 1.2 9.3 1.0 2.2 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 7tm_1 PF00001.21 RUS79068.1 - 1.5e-10 40.9 15.9 3.3e-10 39.7 15.9 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS79068.1 - 7.7e-08 32.3 19.6 1.3e-07 31.5 19.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4149 PF13664.6 RUS79068.1 - 0.28 11.5 5.7 14 6.1 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Collagen PF01391.18 RUS79069.1 - 0.023 14.5 5.7 0.036 13.8 5.7 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) RSN1_7TM PF02714.15 RUS79069.1 - 0.025 13.9 0.4 0.039 13.3 0.4 1.2 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate DUF5416 PF17437.2 RUS79069.1 - 0.056 13.2 1.2 6.4 6.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5416) Laminin_G_2 PF02210.24 RUS79070.1 - 3.9e-118 389.4 8.3 1e-26 94.0 0.1 6.6 6 1 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 RUS79070.1 - 1.2e-92 307.0 0.8 7.2e-22 78.0 0.0 6.6 6 0 0 6 6 6 6 Laminin G domain Laminin_G_3 PF13385.6 RUS79070.1 - 3.2e-09 37.1 3.1 0.0083 16.3 0.1 5.1 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RUS79070.1 - 1.2e-07 31.9 20.6 0.0007 19.8 7.0 2.6 2 0 0 2 2 2 2 EGF-like domain Syndecan PF01034.20 RUS79070.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain hEGF PF12661.7 RUS79070.1 - 0.0028 18.2 15.2 0.25 12.0 2.5 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 RUS79070.1 - 0.3 11.5 27.6 0.48 10.8 9.2 2.7 2 0 0 2 2 2 0 EGF-like domain Phosphorylase PF00343.20 RUS79071.1 - 0 1146.0 0.0 0 1145.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3201 PF11447.8 RUS79071.1 - 0.34 10.4 1.7 21 4.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) RBD PF02196.15 RUS79073.1 - 3.7e-05 23.7 0.0 7.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain RhoGEF PF00621.20 RUS79074.1 - 2.4e-25 89.8 2.0 4.7e-25 88.9 2.0 1.5 1 0 0 1 1 1 1 RhoGEF domain TFIIA PF03153.13 RUS79074.1 - 0.054 13.5 9.5 0.082 12.9 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PH_5 PF15405.6 RUS79074.1 - 0.077 13.1 0.3 0.077 13.1 0.3 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 RUS79074.1 - 0.098 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 PH domain Methyltransf_12 PF08242.12 RUS79074.1 - 0.13 13.0 0.1 0.44 11.3 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain Laminin_G_1 PF00054.23 RUS79075.1 - 0.047 13.9 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Laminin G domain Homeodomain PF00046.29 RUS79076.1 - 3e-23 81.4 0.3 6e-23 80.5 0.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS79076.1 - 0.019 14.9 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF4816 PF16086.5 RUS79077.1 - 6.1 6.9 61.9 1.8e+04 -49.2 61.9 8.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) GRP PF07172.11 RUS79078.1 - 0.0025 18.5 1.3 0.04 14.6 0.8 2.1 2 0 0 2 2 2 1 Glycine rich protein family Sec20 PF03908.13 RUS79078.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Sec20 T2SSM PF04612.12 RUS79078.1 - 0.041 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Orf78 PF06024.12 RUS79078.1 - 0.12 12.7 0.1 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) Peptidase_M13_N PF05649.13 RUS79079.1 - 2.9e-54 185.2 0.2 3.5e-27 96.1 0.5 2.5 1 1 2 3 3 3 2 Peptidase family M13 Peptidase_M13 PF01431.21 RUS79079.1 - 2.2e-49 167.9 1.2 2.3e-36 125.4 0.3 2.6 2 1 1 3 3 3 2 Peptidase family M13 DUF3474 PF11960.8 RUS79080.1 - 6.1 7.0 7.5 18 5.5 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3474) Methyltransf_PK PF05891.12 RUS79081.1 - 8.5e-65 218.3 0.0 9.7e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RUS79081.1 - 2.3e-08 34.7 0.0 3.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS79081.1 - 1.2e-07 32.3 0.0 1.7e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS79081.1 - 3.4e-05 24.5 0.0 5.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 RUS79081.1 - 8.3e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 RUS79081.1 - 0.00046 20.1 0.0 0.00099 19.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RUS79081.1 - 0.0014 17.9 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 RUS79081.1 - 0.0049 16.2 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 RUS79081.1 - 0.033 13.3 0.0 0.077 12.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Bin3 PF06859.12 RUS79081.1 - 0.048 14.3 0.0 0.084 13.5 0.0 1.4 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) PAP2 PF01569.21 RUS79083.1 - 3.4e-14 52.8 8.4 3.4e-14 52.8 8.4 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 RUS79083.1 - 0.016 15.3 1.1 2.5 8.2 0.1 2.5 2 1 0 2 2 2 0 Divergent PAP2 family DEAD PF00270.29 RUS79084.1 - 8.4e-37 126.6 0.2 1.4e-36 125.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS79084.1 - 1.7e-27 96.0 0.3 4.3e-25 88.2 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 RUS79084.1 - 9.5e-08 32.2 0.1 2e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RUS79084.1 - 5.3e-07 29.2 0.1 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UPF0184 PF03670.13 RUS79085.1 - 3.6e-06 27.3 0.5 3.6e-06 27.3 0.5 2.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0184) Sipho_Gp157 PF05565.11 RUS79085.1 - 0.038 14.0 0.9 0.053 13.5 0.9 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4407 PF14362.6 RUS79085.1 - 0.067 12.5 0.5 0.074 12.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TAFH PF07531.14 RUS79085.1 - 0.12 12.5 0.2 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 NHR1 homology to TAF VLPT PF07122.11 RUS79085.1 - 0.14 11.9 1.6 0.27 11.0 1.6 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Ribosomal_L5e PF17144.4 RUS79086.1 - 7.9e-89 295.8 0.6 7.9e-89 295.8 0.6 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RUS79086.1 - 2.6e-34 118.0 10.1 4.2e-34 117.4 8.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region TGT PF01702.18 RUS79087.1 - 3.7e-74 250.0 0.0 4.8e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase IRF-3 PF10401.9 RUS79088.1 - 2.1e-19 70.0 0.0 3.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 RUS79088.1 - 2.9e-18 66.1 1.9 3.1e-18 66.0 0.4 1.9 2 0 0 2 2 2 1 Interferon regulatory factor transcription factor MH2 PF03166.14 RUS79088.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 MH2 domain Innexin PF00876.18 RUS79089.1 - 1.6e-07 31.0 7.9 7.8e-06 25.4 3.5 2.8 2 1 0 2 2 2 2 Innexin DUF2722 PF10846.8 RUS79089.1 - 0.00065 18.8 1.9 0.00079 18.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 RUS79089.1 - 0.072 14.1 2.5 0.26 12.3 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Anoctamin PF04547.12 RUS79089.1 - 0.11 11.3 0.1 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Calcium-activated chloride channel EOS1 PF12326.8 RUS79089.1 - 2.2 8.2 6.8 4.3 7.2 0.0 2.3 1 1 1 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 RUS79089.1 - 8 6.0 20.4 17 4.9 20.4 1.4 1 0 0 1 1 1 0 Spt20 family DAO PF01266.24 RUS79090.1 - 1.2e-48 166.6 0.0 1.4e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS79090.1 - 0.021 15.4 0.0 0.1 13.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 RUS79090.1 - 0.025 14.8 0.2 0.072 13.3 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 RUS79090.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 RUS79090.1 - 0.033 13.4 0.1 0.073 12.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS79090.1 - 0.056 13.7 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 RUS79090.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 RUS79090.1 - 0.15 11.3 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Dynamin_M PF01031.20 RUS79091.1 - 6.8e-84 281.5 9.3 1.1e-61 208.6 4.6 2.9 3 1 1 4 4 4 2 Dynamin central region Dynamin_N PF00350.23 RUS79091.1 - 6.1e-55 185.8 0.0 1.8e-54 184.3 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 RUS79091.1 - 1.7e-23 82.6 1.6 4.4e-23 81.3 1.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 RUS79091.1 - 9.7e-12 45.3 1.1 2e-11 44.4 1.1 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 RUS79091.1 - 0.00026 21.1 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Torsin PF06309.11 RUS79092.1 - 5.2e-19 68.6 0.1 3e-17 62.9 0.1 2.5 1 1 0 1 1 1 1 Torsin UBA_3 PF09288.10 RUS79092.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Mucin-like PF16058.5 RUS79092.1 - 5.8 7.1 9.4 10 6.2 4.1 2.3 2 0 0 2 2 2 0 Mucin-like IQ PF00612.27 RUS79093.1 - 1.2e-94 301.4 317.5 0.00016 21.2 0.8 51.8 53 0 0 53 53 53 37 IQ calmodulin-binding motif ASH PF15780.5 RUS79093.1 - 3.7e-25 88.0 0.0 1.2e-24 86.4 0.0 2.0 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 RUS79093.1 - 7e-18 64.8 0.1 9.8e-08 32.2 0.0 4.1 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS79093.1 - 5.8e-09 35.7 0.0 1.4e-06 28.0 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 RUS79093.1 - 0.00055 20.0 0.1 0.52 10.5 0.0 3.7 3 0 0 3 3 3 2 CH-like domain in sperm protein TMEM131_like PF12371.8 RUS79093.1 - 0.016 15.5 0.1 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 131-like Gal-3-0_sulfotr PF06990.11 RUS79094.1 - 4.7e-44 150.9 0.4 6.6e-44 150.4 0.4 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS79094.1 - 0.0022 17.9 0.1 0.0098 15.8 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family Transglut_C PF00927.22 RUS79095.1 - 5.8e-11 42.5 0.0 4.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 RUS79095.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family Transglut_N PF00868.20 RUS79096.1 - 1.3e-26 93.3 0.0 2.8e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family zf-MYND PF01753.18 RUS79097.1 - 0.00038 20.5 15.0 0.00085 19.4 15.0 1.6 1 0 0 1 1 1 1 MYND finger CDC45 PF02724.14 RUS79097.1 - 0.067 11.5 15.8 0.078 11.3 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 RUS79097.1 - 0.22 11.8 15.6 0.41 10.9 15.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TFIIF_alpha PF05793.12 RUS79097.1 - 0.36 9.4 23.9 0.49 8.9 23.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rhodanese_C PF12368.8 RUS79097.1 - 0.4 11.1 10.7 1.2 9.6 10.7 1.8 1 0 0 1 1 1 0 Rhodanase C-terminal DUF2052 PF09747.9 RUS79097.1 - 0.85 9.7 20.7 1.3 9.1 20.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) LAP1C PF05609.12 RUS79097.1 - 2.1 7.3 16.9 2.5 7.1 16.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 RUS79097.1 - 3 6.6 15.3 3.8 6.3 15.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRN3 PF05327.11 RUS79097.1 - 3.3 6.1 5.8 3.9 5.9 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 RUS79097.1 - 3.9 6.1 18.3 5.9 5.5 18.3 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 RUS79097.1 - 4.6 6.4 7.4 5.3 6.2 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 RUS79097.1 - 4.7 5.8 7.6 5.6 5.5 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 RUS79097.1 - 6.3 5.2 16.4 7.5 5.0 16.4 1.1 1 0 0 1 1 1 0 Macoilin family zf-MYND PF01753.18 RUS79098.1 - 3.3e-08 33.5 5.6 3.3e-08 33.5 5.6 2.3 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.16 RUS79098.1 - 6.8 6.7 8.6 1.4 8.8 4.6 2.0 2 0 0 2 2 2 0 HIT zinc finger CK_II_beta PF01214.18 RUS79099.1 - 6.7e-85 283.5 0.0 7.7e-85 283.3 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DpnI PF06044.12 RUS79099.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing family zf-TFIIB PF13453.6 RUS79099.1 - 0.23 10.8 1.2 2.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger WD40 PF00400.32 RUS79100.1 - 1.4e-26 92.1 15.1 4.7e-07 30.4 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79100.1 - 1.4e-08 34.9 0.0 0.76 10.1 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS79100.1 - 6.2e-06 25.1 0.6 0.002 16.9 0.1 3.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS79100.1 - 0.028 13.8 0.0 1.8 7.8 0.0 2.8 3 1 0 3 3 3 0 WD40-like domain DUF1205 PF06722.12 RUS79100.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Ocnus PF05005.15 RUS79101.1 - 2.8e-38 130.3 0.4 3.3e-38 130.1 0.4 1.1 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) dsrm PF00035.26 RUS79102.1 - 0.022 15.5 0.0 6.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif LAP1C PF05609.12 RUS79103.1 - 4.7e-24 85.3 0.0 7.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Filament PF00038.21 RUS79104.1 - 0.00054 19.7 31.2 0.13 11.9 11.4 3.6 1 1 1 3 3 3 2 Intermediate filament protein HrpB7 PF09486.10 RUS79104.1 - 0.0044 17.4 26.2 0.03 14.7 7.3 3.3 2 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB7) Laminin_II PF06009.12 RUS79104.1 - 0.0055 16.7 11.7 0.16 12.0 1.0 3.5 1 1 2 3 3 3 2 Laminin Domain II Golgin_A5 PF09787.9 RUS79104.1 - 0.013 15.0 35.8 0.14 11.6 15.3 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 BRE1 PF08647.11 RUS79104.1 - 0.014 15.5 0.7 0.014 15.5 0.7 4.5 3 1 1 5 5 4 0 BRE1 E3 ubiquitin ligase CCDC144C PF14915.6 RUS79104.1 - 0.022 13.9 35.1 0.16 11.1 12.0 3.0 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region BORCS8 PF10167.9 RUS79104.1 - 0.03 14.3 1.0 0.03 14.3 1.0 3.0 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 8 IFT57 PF10498.9 RUS79104.1 - 0.032 13.2 21.9 0.26 10.2 5.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 APG6_N PF17675.1 RUS79104.1 - 0.052 14.1 38.0 0.21 12.1 10.4 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region NYD-SP28_assoc PF14775.6 RUS79104.1 - 0.61 10.2 10.2 31 4.8 0.2 4.8 4 1 1 5 5 5 0 Sperm tail C-terminal domain Spc7 PF08317.11 RUS79104.1 - 0.62 8.9 35.6 0.38 9.6 17.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 RUS79104.1 - 0.75 10.2 37.9 0.37 11.2 13.2 2.7 1 1 2 3 3 3 0 Fez1 Phage_GP20 PF06810.11 RUS79104.1 - 1.9 8.3 19.4 0.59 9.9 0.4 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF1664 PF07889.12 RUS79104.1 - 3.3 7.8 18.1 7.5 6.6 5.4 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 RUS79104.1 - 5 7.2 35.5 0.32 11.1 8.5 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus LsmAD PF06741.13 RUS79104.1 - 6 7.5 8.3 4.4 7.9 1.3 3.2 2 1 0 2 2 2 0 LsmAD domain Neur_chan_LBD PF02931.23 RUS79105.1 - 9.5e-37 126.5 1.1 1.2e-36 126.2 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS79105.1 - 3.8e-27 95.9 2.5 5.5e-27 95.4 2.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PhrC_PhrF PF11131.8 RUS79105.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling DUF2618 PF10940.8 RUS79107.1 - 0.014 15.2 1.6 35 4.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) Thioredoxin_9 PF14595.6 RUS79107.1 - 0.028 14.2 4.9 11 5.8 0.0 3.9 1 1 3 4 4 4 0 Thioredoxin Lipoprotein_20 PF13942.6 RUS79107.1 - 0.64 9.9 4.0 59 3.5 0.1 3.9 1 1 3 4 4 4 0 YfhG lipoprotein BSD PF03909.17 RUS79107.1 - 1.5 8.9 5.2 1.4e+02 2.5 0.0 4.5 7 0 0 7 7 7 0 BSD domain FOXP-CC PF16159.5 RUS79107.1 - 2.2 9.0 18.0 1.9 9.2 2.6 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain Cecropin PF00272.19 RUS79108.1 - 0.0019 17.8 0.6 1.3e+02 2.4 0.0 4.8 5 0 0 5 5 5 0 Cecropin family PRR20 PF15708.5 RUS79108.1 - 4 7.3 9.5 40 4.0 1.0 3.6 1 1 3 4 4 4 0 Proline-rich protein family 20 UMP1 PF05348.11 RUS79109.1 - 8.2e-24 84.1 0.6 1e-23 83.8 0.6 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 LEM PF03020.15 RUS79113.1 - 6.6e-05 22.4 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 LEM domain Ank_2 PF12796.7 RUS79113.1 - 0.00035 21.1 0.0 0.002 18.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS79113.1 - 0.016 15.6 0.0 0.082 13.4 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 RUS79113.1 - 0.085 13.5 0.1 1.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79113.1 - 0.15 12.7 0.1 0.71 10.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat PTEN_C2 PF10409.9 RUS79114.1 - 9.3e-21 74.0 0.1 1.7e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RUS79114.1 - 1.2e-06 28.3 0.1 4.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.31 RUS79114.1 - 2.1e-05 23.9 12.8 3e-05 23.4 12.8 1.2 1 0 0 1 1 1 1 Ion transport protein PTPlike_phytase PF14566.6 RUS79114.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RUS79114.1 - 0.0082 15.7 0.0 0.0082 15.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS79114.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Lig_chan-Glu_bd PF10613.9 RUS79115.1 - 3e-35 120.9 0.0 7.9e-35 119.5 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 RUS79115.1 - 6.2e-31 107.2 0.3 1.3e-30 106.2 0.3 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS79115.1 - 7.4e-18 64.8 0.0 6.9e-15 55.1 0.0 3.3 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 RUS79115.1 - 1.8e-09 37.2 0.2 3.1e-08 33.1 0.2 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 RUS79118.1 - 1.8e-11 43.7 0.0 4.1e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS79118.1 - 8.5e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein PH_16 PF17838.1 RUS79118.1 - 0.087 12.7 1.2 3.3 7.6 0.1 2.8 2 1 1 3 3 3 0 PH domain WH2 PF02205.20 RUS79119.1 - 0.0003 20.5 0.1 0.00077 19.2 0.1 1.7 1 0 0 1 1 1 1 WH2 motif Str_synth PF03088.16 RUS79120.1 - 1.4e-19 70.0 0.0 2.8e-14 53.0 0.0 2.9 2 1 1 3 3 3 2 Strictosidine synthase SGL PF08450.12 RUS79120.1 - 5.6e-12 45.8 0.0 1.1e-10 41.5 0.0 2.6 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RUS79120.1 - 4.7e-08 32.7 0.0 2.2 8.5 0.0 5.4 4 0 0 4 4 4 4 NHL repeat SLC35F PF06027.12 RUS79121.1 - 3.5e-96 322.2 28.4 4.1e-96 322.0 28.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 RUS79121.1 - 3.2e-13 50.0 28.6 7.6e-08 32.6 13.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 RUS79121.1 - 3.5e-10 39.4 6.5 3.5e-10 39.4 6.5 2.4 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 RUS79121.1 - 1.5e-07 30.9 22.2 2.2e-07 30.4 22.2 1.2 1 0 0 1 1 1 1 UAA transporter family Ras PF00071.22 RUS79122.1 - 6.7e-57 191.6 0.0 7.8e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS79122.1 - 5.6e-31 107.3 0.0 8.9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS79122.1 - 5.8e-16 58.4 0.0 7.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS79122.1 - 2.1e-07 30.5 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS79122.1 - 4.4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS79122.1 - 0.0052 16.7 0.0 0.71 9.8 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase Raptor_N PF14538.6 RUS79122.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain FeoB_N PF02421.18 RUS79122.1 - 0.14 11.7 0.0 9.7 5.7 0.0 2.7 2 1 1 3 3 3 0 Ferrous iron transport protein B Somatomedin_B PF01033.17 RUS79123.1 - 0.00015 22.1 10.5 0.00015 22.1 10.5 2.0 2 0 0 2 2 2 1 Somatomedin B domain DUF3952 PF13130.6 RUS79123.1 - 0.72 10.1 2.6 13 6.0 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3952) C2 PF00168.30 RUS79124.1 - 1.3e-06 28.6 0.0 8.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain tRNA-synt_2d PF01409.20 RUS79125.1 - 1.3e-46 159.1 0.8 5.9e-28 98.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RUS79125.1 - 3e-25 88.5 0.0 6.7e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 RUS79125.1 - 0.0043 16.2 0.0 0.69 8.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Complex1_LYR PF05347.15 RUS79126.1 - 5.6e-17 61.5 0.4 7.1e-17 61.2 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS79126.1 - 1.2e-07 32.4 0.3 1.4e-07 32.2 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Cadherin_C_2 PF16492.5 RUS79127.1 - 0.37 11.6 1.8 2 9.2 0.1 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Claudin_2 PF13903.6 RUS79128.1 - 5.4e-08 32.8 4.4 3.2e-07 30.3 4.4 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4735 PF15882.5 RUS79129.1 - 2.6e-72 243.7 0.0 4.1e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) Cdd1 PF11731.8 RUS79129.1 - 0.039 14.2 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 Pathogenicity locus Coatomer_WDAD PF04053.14 RUS79130.1 - 1.7e-153 511.9 0.0 8.8e-153 509.5 0.0 2.0 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 RUS79130.1 - 1.8e-36 123.5 7.4 3.4e-07 30.8 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79130.1 - 3.3e-09 36.9 0.0 1.1 9.6 0.0 6.4 3 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS79130.1 - 0.04 12.6 0.1 0.72 8.4 0.0 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sybindin PF04099.12 RUS79131.1 - 1.9e-51 173.8 0.0 2.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RUS79131.1 - 2.7e-07 30.8 0.0 3.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PDZ_6 PF17820.1 RUS79131.1 - 0.05 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain UreF PF01730.16 RUS79132.1 - 1.3e-19 71.1 0.5 4.9e-19 69.2 0.5 1.8 1 1 0 1 1 1 1 UreF LPG_synthase_TM PF03706.13 RUS79133.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region RNA_pol_Rpb4 PF03874.16 RUS79134.1 - 2.1e-25 89.4 8.4 2.9e-25 89.0 8.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tfb4 PF03850.14 RUS79134.1 - 0.036 13.6 1.5 0.034 13.6 1.5 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 SesA PF17107.5 RUS79134.1 - 0.3 11.3 4.3 0.25 11.5 1.0 2.1 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Zip PF02535.22 RUS79137.1 - 1e-39 136.7 12.4 4.4e-39 134.6 12.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter MIG-14_Wnt-bd PF06664.12 RUS79137.1 - 1.7 7.8 8.6 0.062 12.5 1.1 2.2 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion LRR_5 PF13306.6 RUS79138.1 - 0.00096 19.1 0.0 0.0067 16.4 0.0 1.9 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) DASH_Hsk3 PF08227.11 RUS79138.1 - 0.0021 18.4 0.0 1.7e+02 2.6 0.0 5.4 5 1 1 6 6 6 0 DASH complex subunit Hsk3 like RL10P_insert PF17777.1 RUS79138.1 - 0.0042 17.1 0.4 44 4.2 0.0 4.2 1 1 2 3 3 3 1 Insertion domain in 60S ribosomal protein L10P BESS PF02944.20 RUS79138.1 - 0.025 14.4 1.0 75 3.3 0.0 4.6 5 0 0 5 5 5 0 BESS motif Zip PF02535.22 RUS79139.1 - 9.9e-47 159.8 24.7 6.1e-33 114.4 15.6 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter MIG-14_Wnt-bd PF06664.12 RUS79139.1 - 0.0064 15.7 4.3 0.011 15.0 3.5 1.9 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2452 PF10504.9 RUS79142.1 - 3.6e-70 234.4 0.0 4.3e-70 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) DUF2721 PF11026.8 RUS79142.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) GIDA_assoc PF13932.6 RUS79143.1 - 3.6e-27 95.9 0.1 4e-27 95.8 0.1 1.0 1 0 0 1 1 1 1 GidA associated domain ABC1 PF03109.16 RUS79143.1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.6 2 0 0 2 2 2 0 ABC1 family GIDA PF01134.22 RUS79144.1 - 7.7e-140 466.4 0.0 8.8e-140 466.2 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 RUS79144.1 - 1.9e-07 30.8 1.5 2.6e-07 30.4 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS79144.1 - 0.0001 21.6 5.1 0.00015 21.0 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS79144.1 - 0.00027 20.3 1.7 0.00053 19.3 1.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RUS79144.1 - 0.00063 19.1 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RUS79144.1 - 0.0091 14.7 0.4 0.014 14.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 RUS79144.1 - 0.014 14.7 0.6 0.15 11.3 0.2 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 RUS79144.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS79144.1 - 0.018 15.6 0.3 0.037 14.6 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dscam_C PF12355.8 RUS79145.1 - 1.9 9.5 8.0 3.2 8.7 0.1 2.8 2 1 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Mito_fiss_reg PF05308.11 RUS79145.1 - 4.1 7.4 4.4 2.7 8.0 0.8 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 RUS79145.1 - 4.5 6.7 9.0 0.24 10.8 1.9 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 RUS79145.1 - 7.5 5.9 6.0 0.82 9.1 0.8 1.8 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein GLTP PF08718.11 RUS79146.1 - 6e-32 111.0 0.0 1.3e-31 109.8 0.0 1.6 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF1955 PF09205.10 RUS79146.1 - 0.053 13.3 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) ITAM_Cys-rich PF10538.9 RUS79146.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif TPH PF13868.6 RUS79147.1 - 3.9e-31 107.9 148.3 3.9e-31 107.9 148.3 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain IL17 PF06083.11 RUS79148.1 - 5e-13 49.3 4.3 8.2e-13 48.6 4.3 1.3 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.11 RUS79149.1 - 5.6e-14 52.4 3.9 1.1e-13 51.5 3.9 1.5 1 0 0 1 1 1 1 Interleukin-17 TCR_zetazeta PF11628.8 RUS79150.1 - 0.0017 17.9 10.6 0.2 11.4 0.2 3.2 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 zeta chain DNA_RNApol_7kD PF03604.13 RUS79151.1 - 0.006 16.2 1.5 0.48 10.1 0.1 2.4 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 RUS79151.1 - 0.01 15.4 0.7 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_recom PF13408.6 RUS79151.1 - 0.14 12.7 1.2 4.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-CRD PF17979.1 RUS79152.1 - 4.6e-36 124.3 10.3 4.6e-36 124.3 10.3 2.6 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 RUS79152.1 - 7e-13 48.7 0.1 1.3e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 RUS79152.1 - 8.7e-08 31.9 14.1 8.7e-08 31.9 14.1 3.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 RUS79152.1 - 1.4e-06 28.2 4.1 1.4e-06 28.2 4.1 3.1 2 0 0 2 2 2 1 PBZ domain zf-RING_2 PF13639.6 RUS79152.1 - 1.8e-06 28.2 14.2 1.8e-06 28.2 14.2 4.5 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS79152.1 - 1.8e-06 27.7 10.7 1.8e-06 27.7 10.7 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS79152.1 - 2.1e-05 24.3 14.8 2.1e-05 24.3 14.8 4.0 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 RUS79152.1 - 0.00012 22.2 8.3 0.00012 22.2 8.3 4.1 4 1 0 4 4 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 RUS79152.1 - 0.00071 19.4 11.6 0.00071 19.4 11.6 3.5 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 Yop-YscD_cpl PF16697.5 RUS79152.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_6 PF14835.6 RUS79152.1 - 0.0034 17.2 4.9 0.0034 17.2 4.9 3.5 4 0 0 4 4 3 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RUS79152.1 - 0.006 16.9 9.8 0.006 16.9 9.8 3.9 4 1 0 4 4 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS79152.1 - 0.012 15.5 11.5 0.012 15.5 11.5 3.7 3 0 0 3 3 2 0 zinc-RING finger domain DUF5003 PF16394.5 RUS79152.1 - 0.017 14.2 1.2 0.13 11.4 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5003) Macoilin PF09726.9 RUS79152.1 - 2.1 6.8 5.6 2.7 6.5 5.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF4611 PF15387.6 RUS79152.1 - 5.9 7.2 8.9 0.27 11.5 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 RUS79153.1 - 1e-67 228.3 0.0 1.7e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79153.1 - 3e-49 167.7 0.0 4.9e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 RUS79153.1 - 2.3e-14 53.4 5.1 5e-14 52.3 5.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 RUS79153.1 - 4.8e-05 22.8 0.0 9.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RUS79153.1 - 0.00013 21.6 0.1 0.00042 20.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 RUS79153.1 - 0.00031 20.2 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS79153.1 - 0.0036 16.1 0.0 0.014 14.2 0.0 2.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS79153.1 - 0.14 12.1 0.2 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3456 PF11938.8 RUS79154.1 - 2.2e-07 31.5 2.3 9e-07 29.5 0.7 2.4 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Neur_chan_LBD PF02931.23 RUS79155.1 - 1.8e-19 70.0 0.0 2.7e-19 69.5 0.0 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain FAR1 PF03101.15 RUS79156.1 - 0.0004 21.0 0.1 0.00068 20.3 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain HECA PF15353.6 RUS79156.1 - 0.0053 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Headcase protein family homologue Tap-RNA_bind PF09162.10 RUS79156.1 - 0.13 12.1 1.8 0.97 9.3 0.4 2.4 2 0 0 2 2 2 0 Tap, RNA-binding Copine PF07002.16 RUS79157.1 - 7.2e-63 211.9 0.0 8.7e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RUS79157.1 - 2.5e-09 37.6 0.0 3.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 RUS79157.1 - 0.017 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2798 PF11391.8 RUS79158.1 - 0.18 11.9 59.0 7.2 6.7 6.7 5.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2798) 2HCT PF03390.15 RUS79158.1 - 0.19 10.3 12.5 0.29 9.7 0.9 3.1 1 1 2 3 3 3 0 2-hydroxycarboxylate transporter family Gly-zipper_Omp PF13488.6 RUS79158.1 - 0.69 10.0 11.8 51 4.0 8.0 3.7 2 1 0 2 2 2 0 Glycine zipper Romo1 PF10247.9 RUS79158.1 - 0.81 10.1 12.9 11 6.5 3.2 3.8 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 RNA_pol_L_2 PF13656.6 RUS79159.1 - 1.5e-28 98.4 0.0 1.9e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RUS79159.1 - 7.6e-09 34.9 0.0 1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 RUS79159.1 - 0.0046 16.4 0.0 0.012 15.1 0.0 1.7 1 1 1 2 2 2 1 SHNi-TPR Myb_DNA-bind_2 PF08914.11 RUS79161.1 - 6.8e-16 58.2 0.1 1.4e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 RUS79161.1 - 1.8e-10 41.1 0.0 1.2e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Phage_int_SAM_3 PF14659.6 RUS79161.1 - 0.053 13.8 0.3 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Rap1-DNA-bind PF09197.10 RUS79161.1 - 0.089 13.4 0.5 0.19 12.3 0.5 1.7 1 1 0 1 1 1 0 Rap1, DNA-binding HAUS6_N PF14661.6 RUS79166.1 - 0.022 14.4 0.9 0.029 13.9 0.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SNF PF00209.18 RUS79168.1 - 1.7e-155 518.7 35.8 2e-155 518.4 35.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RPA_interact_N PF14766.6 RUS79169.1 - 1.2e-11 44.0 4.6 2.2e-11 43.2 4.6 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.6 RUS79169.1 - 0.0002 21.9 5.4 0.0002 21.9 5.4 2.2 3 0 0 3 3 3 1 Replication protein A interacting C-terminal zf-Di19 PF05605.12 RUS79169.1 - 0.034 14.4 0.7 0.089 13.1 0.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Spore_II_R PF09551.10 RUS79170.1 - 5.4e-09 36.6 1.5 2.9 8.4 0.0 4.8 1 1 7 8 8 8 8 Stage II sporulation protein R (spore_II_R) Pentapeptide_4 PF13599.6 RUS79170.1 - 1e-05 25.6 0.0 0.017 15.3 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) PMG PF05287.12 RUS79170.1 - 0.0036 17.4 25.4 0.67 10.0 8.5 2.8 1 1 2 3 3 3 3 PMG protein Lamprin PF06403.11 RUS79170.1 - 0.021 14.8 0.0 3.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Lamprin C166 PF17615.2 RUS79170.1 - 0.29 11.3 17.6 1.1e+03 -0.3 17.6 3.4 1 1 0 1 1 1 0 Family of unknown function WD40 PF00400.32 RUS79171.1 - 1.8e-13 50.7 9.5 0.00056 20.7 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79171.1 - 4.5e-08 33.3 0.0 0.041 14.2 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS79171.1 - 0.00014 21.0 0.2 0.0005 19.1 0.2 1.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS79171.1 - 0.00024 21.1 0.1 0.21 11.4 0.0 3.4 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS1 PF14779.6 RUS79171.1 - 0.028 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DTC PF18102.1 RUS79172.1 - 5.9e-44 149.4 0.0 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 RUS79172.1 - 7e-21 74.6 0.6 9.6e-13 48.5 0.5 2.5 2 0 0 2 2 2 2 WWE domain zf-C3HC4 PF00097.25 RUS79172.1 - 6e-05 22.8 11.4 0.00012 21.9 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS79172.1 - 0.001 19.3 11.4 0.0025 18.1 11.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 RUS79172.1 - 0.043 13.9 4.3 0.09 12.8 4.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RUS79172.1 - 0.12 12.6 9.9 0.28 11.5 9.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Spt20 PF12090.8 RUS79172.1 - 0.21 11.1 2.8 0.37 10.3 2.8 1.4 1 0 0 1 1 1 0 Spt20 family FANCL_C PF11793.8 RUS79172.1 - 0.33 11.2 7.8 0.67 10.2 7.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 RUS79172.1 - 2 8.3 12.9 0.26 11.2 4.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Usp PF00582.26 RUS79173.1 - 2.9e-28 99.1 1.0 3.6e-28 98.9 1.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Laminin_EGF PF00053.24 RUS79174.1 - 3.7e-05 23.8 23.3 0.00068 19.7 12.8 2.3 1 1 1 2 2 2 2 Laminin EGF domain ANF_receptor PF01094.28 RUS79176.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Gti1_Pac2 PF09729.9 RUS79177.1 - 8.2 6.5 20.3 0.51 10.4 14.1 1.9 2 0 0 2 2 2 0 Gti1/Pac2 family NPR3 PF03666.13 RUS79177.1 - 8.8 5.0 17.4 17 4.0 17.4 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Radial_spoke PF04712.12 RUS79178.1 - 4.7e-117 391.9 9.9 1e-74 252.3 2.7 3.0 3 1 0 3 3 3 2 Radial spokehead-like protein Ig_2 PF13895.6 RUS79179.1 - 0.011 16.0 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain CENP-B_dimeris PF09026.10 RUS79179.1 - 0.021 15.2 1.7 0.021 15.2 1.7 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.12 RUS79179.1 - 0.084 12.4 0.4 0.57 9.7 0.3 2.0 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FAM176 PF14851.6 RUS79179.1 - 0.16 11.6 1.4 0.45 10.2 0.9 1.9 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 RUS79179.1 - 0.19 12.1 0.2 0.19 12.1 0.2 2.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 RUS79179.1 - 0.38 10.8 4.8 0.074 13.1 1.0 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 RUS79179.1 - 3.7 6.8 4.7 7 5.9 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein GTPase_binding PF09027.10 RUS79180.1 - 0.15 12.0 5.2 2.3e+02 1.9 0.0 5.7 4 3 2 7 7 7 0 GTPase binding DUF3439 PF11921.8 RUS79182.1 - 1 9.4 5.6 2.4 8.1 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RT_RNaseH_2 PF17919.1 RUS79183.1 - 2.4e-16 59.6 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS79183.1 - 9e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ras PF00071.22 RUS79184.1 - 1.4e-31 109.3 0.0 5.1e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RUS79184.1 - 3e-22 79.1 0.0 5.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS79184.1 - 5.2e-06 26.0 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS79184.1 - 5.3e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MCM PF00493.23 RUS79184.1 - 0.0017 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_18 PF13238.6 RUS79184.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RUS79184.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 RUS79184.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RUS79184.1 - 0.018 14.9 0.1 0.052 13.5 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 RUS79184.1 - 0.02 14.1 0.4 0.036 13.2 0.4 1.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 RUS79184.1 - 0.023 14.2 0.2 0.039 13.5 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 RUS79184.1 - 0.023 15.2 0.0 0.081 13.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 RUS79184.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 RUS79184.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.14 RUS79184.1 - 0.064 13.3 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 RUS79184.1 - 0.078 12.3 0.4 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 RUS79184.1 - 0.089 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 RUS79184.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 RUS79184.1 - 0.15 12.4 0.1 0.27 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RUS79184.1 - 0.17 12.2 0.0 0.37 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Macoilin PF09726.9 RUS79184.1 - 0.3 9.6 1.5 0.35 9.4 1.5 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 RUS79184.1 - 2.1 6.6 4.8 3.2 6.0 4.8 1.2 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 RUS79184.1 - 5.6 7.6 22.6 17 6.1 22.6 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain IL17 PF06083.11 RUS79185.1 - 0.011 16.2 2.2 1.6 9.3 0.1 2.3 1 1 1 2 2 2 0 Interleukin-17 Nup88 PF10168.9 RUS79186.1 - 1.2e-22 79.6 7.7 1.3e-22 79.5 7.7 1.0 1 0 0 1 1 1 1 Nuclear pore component KxDL PF10241.9 RUS79186.1 - 0.0059 16.9 2.6 0.64 10.3 0.4 2.3 2 1 0 2 2 2 2 Uncharacterized conserved protein IFT57 PF10498.9 RUS79186.1 - 0.025 13.6 7.6 0.044 12.7 7.6 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 RUS79186.1 - 0.049 13.7 1.1 6.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 RUS79186.1 - 0.07 13.6 0.1 0.07 13.6 0.1 3.0 2 1 1 3 3 3 0 Cell division protein ZapB GCD14 PF08704.10 RUS79186.1 - 0.12 12.0 1.1 0.13 11.9 1.1 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AAA_23 PF13476.6 RUS79186.1 - 0.19 12.2 6.3 0.25 11.8 6.3 1.2 1 0 0 1 1 1 0 AAA domain THOC7 PF05615.13 RUS79186.1 - 0.3 11.4 9.1 1.3 9.3 3.7 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 DUF745 PF05335.13 RUS79186.1 - 0.35 10.6 4.4 0.62 9.8 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Nup54 PF13874.6 RUS79186.1 - 0.41 10.8 8.7 0.092 12.8 2.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Rx_N PF18052.1 RUS79186.1 - 0.44 10.9 4.9 5.6 7.3 0.2 2.6 2 1 0 2 2 2 0 Rx N-terminal domain DUF1664 PF07889.12 RUS79186.1 - 0.66 10.0 6.8 0.46 10.5 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 RUS79186.1 - 2.3 7.4 6.7 7.2 5.8 6.7 1.8 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 RUS79186.1 - 3.6 7.8 12.6 34 4.6 12.6 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HR1 PF02185.16 RUS79186.1 - 5 7.3 13.4 1e+02 3.1 10.7 2.8 1 1 1 2 2 2 0 Hr1 repeat DUF16 PF01519.16 RUS79186.1 - 5.8 7.5 8.9 52 4.4 8.9 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin PF02996.17 RUS79186.1 - 6.8 6.6 11.7 3.1 7.7 0.4 3.0 2 1 0 3 3 3 0 Prefoldin subunit Nup88 PF10168.9 RUS79187.1 - 1.4e-123 413.2 1.0 2.6e-64 217.3 0.0 2.4 1 1 1 2 2 2 2 Nuclear pore component CUT PF02376.15 RUS79188.1 - 2.1e-76 252.1 1.2 2.1e-25 88.7 0.0 4.0 4 0 0 4 4 4 3 CUT domain Homeodomain PF00046.29 RUS79188.1 - 3.1e-16 59.0 0.1 9.8e-16 57.4 0.1 2.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS79188.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DegS PF05384.11 RUS79188.1 - 0.0041 16.6 0.6 0.0041 16.6 0.6 4.4 4 0 0 4 4 4 1 Sensor protein DegS YdaS_antitoxin PF15943.5 RUS79188.1 - 0.025 14.4 0.1 0.51 10.3 0.0 2.9 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_ISL3 PF13542.6 RUS79188.1 - 0.054 12.9 0.0 0.18 11.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ApoO PF09769.9 RUS79188.1 - 0.14 12.1 7.2 1.2 9.1 1.3 3.6 2 1 0 3 3 3 0 Apolipoprotein O HTH_ABP1_N PF18107.1 RUS79188.1 - 0.22 11.2 4.5 20 5.0 0.0 4.4 5 0 0 5 5 5 0 Fission yeast centromere protein N-terminal domain Noggin PF05806.12 RUS79188.1 - 1 9.3 5.1 3.4 7.5 5.1 1.9 1 0 0 1 1 1 0 Noggin CASP_C PF08172.12 RUS79190.1 - 1.2e-51 175.5 10.2 1.6e-47 162.0 8.2 2.9 2 1 0 2 2 2 2 CASP C terminal CtIP_N PF10482.9 RUS79190.1 - 0.0011 19.0 2.9 0.0011 19.0 2.9 2.0 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DUF2205 PF10224.9 RUS79190.1 - 0.0077 16.2 0.9 0.0077 16.2 0.9 2.0 2 0 0 2 2 2 1 Short coiled-coil protein NPV_P10 PF05531.12 RUS79190.1 - 0.042 14.3 1.1 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 RUS79190.1 - 0.043 13.5 0.9 0.043 13.5 0.9 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 RUS79190.1 - 0.052 13.9 2.0 0.1 13.0 0.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CCDC168_N PF15804.5 RUS79190.1 - 0.083 12.7 0.1 0.083 12.7 0.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 168 NDUF_B8 PF05821.11 RUS79190.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) UPF0231 PF06062.11 RUS79190.1 - 0.12 12.6 0.1 0.82 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) TMF_TATA_bd PF12325.8 RUS79190.1 - 0.14 12.4 6.0 2.9 8.1 0.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1465 PF07323.12 RUS79190.1 - 0.2 11.5 3.2 0.15 11.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Fib_alpha PF08702.10 RUS79190.1 - 0.24 11.6 2.4 3 8.0 0.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 RUS79190.1 - 0.31 11.1 2.1 0.46 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) GIT_CC PF16559.5 RUS79190.1 - 0.32 10.9 5.4 0.2 11.5 2.9 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 RUS79190.1 - 0.39 10.8 2.8 18 5.4 0.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 RUS79190.1 - 0.46 11.1 5.7 0.9 10.2 0.7 2.8 2 1 1 3 3 3 0 SlyX DivIC PF04977.15 RUS79190.1 - 1.9 8.3 10.2 0.17 11.6 2.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Golgin_A5 PF09787.9 RUS79190.1 - 7.4 5.9 14.2 34 3.7 9.8 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 DUF229 PF02995.17 RUS79191.1 - 1.2e-101 340.8 2.0 2e-101 340.1 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) VWA PF00092.28 RUS79191.1 - 7.1e-59 199.0 0.0 1.2e-31 110.3 0.1 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS79191.1 - 8.1e-22 77.9 0.0 1.6e-09 38.4 0.0 3.4 4 0 0 4 4 4 2 von Willebrand factor type A domain Sulfatase PF00884.23 RUS79191.1 - 2.3e-06 27.3 0.6 2.3e-05 24.0 0.6 2.1 1 1 0 1 1 1 1 Sulfatase VWA_3 PF13768.6 RUS79191.1 - 1.2e-05 25.3 0.0 5.3e-05 23.2 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Copine PF07002.16 RUS79191.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Copine tRNA-synt_1 PF00133.22 RUS79192.1 - 3.2e-176 587.2 0.0 4.8e-175 583.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RUS79192.1 - 3.9e-35 121.1 0.0 6.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RUS79192.1 - 1.9e-15 56.5 0.2 8.2e-05 21.5 0.1 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RUS79192.1 - 1e-09 38.1 0.1 3.2e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RUS79192.1 - 0.024 14.0 0.0 0.34 10.2 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain YscO PF07321.12 RUS79192.1 - 0.082 12.9 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Guanylate_cyc PF00211.20 RUS79193.1 - 0.0001 22.0 0.1 0.0002 21.0 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AMP-binding PF00501.28 RUS79194.1 - 6.3e-58 196.4 0.0 8.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS79194.1 - 9.2e-06 26.6 0.0 2.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Prefoldin PF02996.17 RUS79195.1 - 1.6e-17 63.5 0.1 2e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tom37_C PF11801.8 RUS79195.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF3712 PF12505.8 RUS79195.1 - 0.18 12.1 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) DUF1664 PF07889.12 RUS79197.1 - 0.24 11.5 0.9 8.2 6.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 RUS79199.1 - 1.5e-18 66.4 0.0 2.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CARD PF00619.21 RUS79199.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Caspase recruitment domain Plasmodium_HRP PF05403.11 RUS79200.1 - 0.00041 20.2 0.2 0.66 9.7 0.1 2.1 1 1 0 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) DUF4573 PF15140.6 RUS79200.1 - 0.00054 19.8 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4573) Lyase_aromatic PF00221.19 RUS79200.1 - 0.011 14.4 3.3 0.51 8.9 0.2 2.2 2 0 0 2 2 2 0 Aromatic amino acid lyase Ion_trans PF00520.31 RUS79200.1 - 0.015 14.5 0.5 2.8 7.1 0.1 2.7 1 1 0 2 2 2 0 Ion transport protein hnRNP_Q_AcD PF18360.1 RUS79200.1 - 1 9.4 6.4 44 4.1 0.7 4.0 2 2 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain NHL PF01436.21 RUS79202.1 - 7.9e-08 32.0 0.0 0.075 13.1 0.0 4.4 4 0 0 4 4 4 1 NHL repeat Fib_alpha PF08702.10 RUS79202.1 - 0.0021 18.2 15.5 0.0021 18.2 15.5 2.4 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family GAS PF13851.6 RUS79202.1 - 0.0025 17.2 30.0 0.0033 16.8 30.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.9 RUS79202.1 - 0.0059 16.9 25.2 0.089 13.1 25.2 2.0 1 1 0 1 1 1 1 Zinc finger-containing protein Tup_N PF08581.10 RUS79202.1 - 0.0065 16.7 22.7 0.03 14.6 9.7 3.0 1 1 2 3 3 3 1 Tup N-terminal HBM PF16591.5 RUS79202.1 - 0.27 10.6 20.7 2 7.8 2.6 2.2 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF1640 PF07798.11 RUS79202.1 - 0.31 11.1 31.2 4.4e+03 -2.5 31.2 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) AIP3 PF03915.13 RUS79202.1 - 0.84 8.7 27.4 0.93 8.5 25.9 1.7 1 1 1 2 2 2 0 Actin interacting protein 3 Spectrin PF00435.21 RUS79202.1 - 0.9 10.1 19.7 21 5.7 4.1 2.7 1 1 1 2 2 2 0 Spectrin repeat betaPIX_CC PF16523.5 RUS79202.1 - 1.2 9.0 29.2 0.38 10.6 2.1 3.8 1 1 4 5 5 5 0 betaPIX coiled coil GREB1 PF15782.5 RUS79202.1 - 1.3 6.0 19.3 1.5 5.8 19.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Syntaxin_2 PF14523.6 RUS79202.1 - 1.7 9.1 26.6 3.7 8.0 6.9 2.8 1 1 1 2 2 2 0 Syntaxin-like protein KASH_CCD PF14662.6 RUS79202.1 - 1.7 8.5 30.8 6 6.7 21.0 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Prominin PF05478.11 RUS79202.1 - 1.7 6.5 14.6 2.2 6.2 14.6 1.1 1 0 0 1 1 1 0 Prominin Adeno_E3_15_3 PF03307.14 RUS79202.1 - 1.8 8.6 8.5 4.9 7.1 3.1 2.6 1 1 1 2 2 2 0 Adenovirus 15.3kD protein in E3 region Atg14 PF10186.9 RUS79202.1 - 2.5 7.1 20.3 3.9 6.5 20.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COMP PF11598.8 RUS79202.1 - 4.4 7.9 14.3 27 5.3 0.4 4.9 2 1 3 5 5 5 0 Cartilage oligomeric matrix protein Rx_N PF18052.1 RUS79202.1 - 5 7.5 17.1 2.9 8.2 5.4 2.9 1 1 2 3 3 3 0 Rx N-terminal domain LMBR1 PF04791.16 RUS79202.1 - 5.2 5.9 14.6 7.1 5.4 14.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF445 PF04286.12 RUS79202.1 - 6 6.6 14.2 8.4 6.1 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Seryl_tRNA_N PF02403.22 RUS79202.1 - 7.5 6.8 27.1 0.55 10.5 17.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-nanos PF05741.13 RUS79203.1 - 0.0019 18.4 1.8 6.4 7.1 0.0 3.2 2 1 1 3 3 3 2 Nanos RNA binding domain Vps55 PF04133.14 RUS79203.1 - 0.077 13.0 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 55 QVR PF17064.5 RUS79204.1 - 8.9e-09 35.5 9.9 1.4e-08 34.9 9.9 1.3 1 0 0 1 1 1 1 Sleepless protein DUF4502 PF14950.6 RUS79205.1 - 0.007 15.8 9.1 0.0075 15.7 9.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) RVT_1 PF00078.27 RUS79206.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Adenine_glyco PF03352.13 RUS79206.1 - 0.042 13.6 0.3 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase CSRNP_N PF16019.5 RUS79207.1 - 0.1 12.5 0.7 0.14 12.0 0.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus EGF PF00008.27 RUS79209.1 - 2.3e-24 85.3 77.3 6.9e-05 23.1 6.4 6.5 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 RUS79209.1 - 8.7e-12 45.2 95.3 0.00032 21.2 4.2 8.2 12 0 0 12 12 12 6 Human growth factor-like EGF EGF_2 PF07974.13 RUS79209.1 - 3.5e-10 40.1 78.6 0.083 13.3 7.1 6.3 6 0 0 6 6 6 6 EGF-like domain NAT PF04768.13 RUS79211.1 - 5.3e-42 143.4 0.2 1.2e-31 109.7 0.3 3.5 3 0 0 3 3 3 3 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_10 PF13673.7 RUS79211.1 - 0.0029 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS79211.1 - 0.0058 16.9 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS79211.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_kinase PF00696.28 RUS79211.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Amino acid kinase family 7tm_1 PF00001.21 RUS79212.1 - 1.2e-08 34.6 6.1 1.4e-08 34.5 6.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS79212.1 - 2.4e-06 27.1 7.1 0.0076 15.6 0.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2417 PF10329.9 RUS79212.1 - 0.012 15.1 0.2 0.012 15.1 0.2 2.2 2 1 0 2 2 2 0 Region of unknown function (DUF2417) DUF5090 PF17009.5 RUS79212.1 - 1.9 8.4 7.8 2.3 8.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF2207 PF09972.9 RUS79212.1 - 5.1 5.7 5.3 1.4 7.6 1.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 RUS79212.1 - 8.4 6.3 9.3 4 7.4 4.8 2.1 1 1 1 2 2 2 0 TMEM154 protein family DUF3267 PF11667.8 RUS79214.1 - 0.71 10.2 5.9 0.78 10.1 0.5 2.6 2 0 0 2 2 2 0 Putative zincin peptidase Clr2_transil PF16761.5 RUS79216.1 - 0.085 13.7 0.1 0.24 12.3 0.1 1.8 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 Deltameth_res PF16020.5 RUS79218.1 - 6.6e-11 41.9 0.0 1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Deltamethrin resistance EAP30 PF04157.16 RUS79219.1 - 1e-45 155.9 0.9 1.4e-45 155.4 0.9 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 RUS79219.1 - 3.3e-14 52.8 0.0 6.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF4268 PF14088.6 RUS79219.1 - 0.012 15.5 0.6 0.022 14.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) BBL5 PF07289.11 RUS79219.1 - 0.027 13.5 0.1 0.11 11.5 0.0 1.9 3 0 0 3 3 3 0 Bardet-Biedl syndrome 5 protein BAR_3 PF16746.5 RUS79219.1 - 0.033 13.9 0.7 0.092 12.4 0.1 1.9 2 0 0 2 2 2 0 BAR domain of APPL family USP8_interact PF08941.10 RUS79219.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 USP8 interacting LON_substr_bdg PF02190.16 RUS79220.1 - 6.5e-23 81.7 0.0 1.7e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 RUS79220.1 - 1.1e-14 54.0 29.2 9.3e-10 38.2 9.4 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS79220.1 - 4.6e-14 52.1 25.7 3.9e-08 33.2 8.3 3.3 3 0 0 3 3 2 2 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS79220.1 - 8.8e-14 51.1 23.7 2.2e-08 33.8 5.2 3.7 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 RUS79220.1 - 1.3e-11 44.2 27.7 8.5e-07 28.8 8.1 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS79220.1 - 1.9e-11 43.7 28.0 3.2e-07 30.2 7.9 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS79220.1 - 4.2e-11 42.5 25.3 6.5e-08 32.3 4.7 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS79220.1 - 1.3e-10 41.3 24.9 1e-05 25.6 7.3 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING TPR_1 PF00515.28 RUS79220.1 - 1.7e-10 40.2 7.5 0.0054 16.5 0.3 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS79220.1 - 1.5e-09 37.2 11.9 0.00095 19.1 1.7 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 RUS79220.1 - 2.2e-09 37.5 30.8 1.7e-07 31.5 8.8 3.6 3 0 0 3 3 3 2 Ring finger domain zf-RING_10 PF16685.5 RUS79220.1 - 4e-07 30.1 16.3 0.00085 19.4 3.8 2.9 2 0 0 2 2 2 2 zinc RING finger of MSL2 U-box PF04564.15 RUS79220.1 - 3.7e-06 27.0 0.1 0.13 12.5 0.0 3.4 3 0 0 3 3 3 2 U-box domain TPR_16 PF13432.6 RUS79220.1 - 5.4e-06 27.0 9.4 0.0014 19.3 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS79220.1 - 3e-05 24.1 4.3 0.014 15.5 3.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS79220.1 - 4.1e-05 23.5 5.8 0.11 12.8 0.1 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS79220.1 - 0.0036 16.9 1.4 0.65 9.7 0.1 3.3 1 1 2 3 3 3 1 TPR repeat TPR_19 PF14559.6 RUS79220.1 - 0.0041 17.6 2.7 2.1 8.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 RUS79220.1 - 0.0062 16.8 4.8 0.0062 16.8 4.8 3.3 3 0 0 3 3 2 1 RING-H2 zinc finger domain TPR_12 PF13424.6 RUS79220.1 - 0.0078 16.5 6.1 5.3 7.4 0.4 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat zf-RING_6 PF14835.6 RUS79220.1 - 0.01 15.7 21.2 0.047 13.6 6.0 2.9 3 0 0 3 3 3 0 zf-RING of BARD1-type protein TPR_7 PF13176.6 RUS79220.1 - 0.039 14.0 2.6 49 4.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat UVR PF02151.19 RUS79220.1 - 0.55 10.0 2.6 2.4 8.0 0.2 3.2 3 0 0 3 3 3 0 UvrB/uvrC motif TPR_14 PF13428.6 RUS79220.1 - 0.72 10.8 6.4 53 5.0 0.9 4.7 3 2 2 5 5 4 0 Tetratricopeptide repeat DUF1272 PF06906.11 RUS79220.1 - 0.98 9.6 17.9 0.23 11.6 2.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 RUS79220.1 - 2.2 8.5 9.1 14 5.9 2.0 2.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 RUS79220.1 - 2.8 7.8 19.2 0.032 14.0 1.8 2.9 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 RUS79220.1 - 4.2 7.1 17.6 1.5 8.5 5.1 2.8 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 RUS79220.1 - 9.4 6.1 18.7 6.5 6.6 0.7 4.3 4 0 0 4 4 3 0 RING-like zinc finger NHL PF01436.21 RUS79222.1 - 4.6e-26 89.5 17.1 5.7e-09 35.6 0.4 6.2 6 0 0 6 6 6 4 NHL repeat zf-B_box PF00643.24 RUS79222.1 - 1.4e-08 34.7 22.2 5.5e-07 29.6 6.3 4.2 4 1 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS79222.1 - 5e-08 32.8 2.7 5e-08 32.8 2.7 3.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS79222.1 - 1.1e-05 25.1 3.4 1.1e-05 25.1 3.4 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SGL PF08450.12 RUS79222.1 - 2.3e-05 24.1 0.3 0.48 10.0 0.0 3.4 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region zf-RING_5 PF14634.6 RUS79222.1 - 4.5e-05 23.3 4.7 4.5e-05 23.3 4.7 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS79222.1 - 7e-05 22.6 6.6 7e-05 22.6 6.6 4.3 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 RUS79222.1 - 0.00024 20.4 2.4 0.62 9.1 0.1 3.5 2 1 1 3 3 3 2 6-bladed beta-propeller Prok-RING_4 PF14447.6 RUS79222.1 - 0.002 17.9 6.3 0.002 17.9 6.3 4.1 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 Pet191_N PF10203.9 RUS79223.1 - 3.3e-24 85.0 5.5 4.5e-24 84.5 5.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 RUS79223.1 - 0.15 12.2 1.3 0.2 11.8 0.2 1.9 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.17 RUS79223.1 - 1 9.7 6.1 16 5.8 1.9 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UNC-50 PF05216.13 RUS79224.1 - 3.4e-88 294.9 22.0 3.9e-88 294.7 22.0 1.0 1 0 0 1 1 1 1 UNC-50 family zf-CSL PF05207.13 RUS79225.1 - 2.8e-23 81.4 2.1 3.7e-23 81.0 2.1 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 RUS79225.1 - 0.0025 17.9 1.6 0.004 17.2 1.6 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 RUS79225.1 - 0.023 13.3 0.4 0.025 13.2 0.4 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.6 RUS79225.1 - 0.029 14.3 0.5 0.044 13.7 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 RUS79225.1 - 0.082 12.7 4.3 0.17 11.7 4.3 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain LINES_N PF14694.6 RUS79225.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Lines N-terminus UQ_con PF00179.26 RUS79226.1 - 5.3e-19 68.2 0.0 9.4e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L27 PF01016.19 RUS79227.1 - 5.5e-15 55.2 0.0 8.2e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Biotin_lipoyl_2 PF13533.6 RUS79227.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like Complex1_LYR PF05347.15 RUS79229.1 - 3.7e-06 26.9 5.7 3.7e-06 26.9 5.7 1.9 2 1 0 2 2 2 1 Complex 1 protein (LYR family) RGS_DHEX PF18148.1 RUS79229.1 - 0.017 15.2 0.9 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain STAT_alpha PF01017.20 RUS79229.1 - 0.073 13.0 0.2 0.099 12.5 0.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain EMP24_GP25L PF01105.24 RUS79230.1 - 2.7e-53 180.6 1.4 3.1e-53 180.4 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF658 PF04936.12 RUS79230.1 - 0.007 16.1 0.2 0.013 15.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF658) PNP_UDP_1 PF01048.20 RUS79231.1 - 5.6e-47 160.0 0.1 6.4e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C3HC4 PF00097.25 RUS79232.1 - 7e-05 22.6 18.3 0.0001 22.1 18.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79232.1 - 8.8e-05 22.3 14.3 0.00012 21.8 14.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS79232.1 - 0.00051 19.8 17.0 0.00071 19.4 17.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS79232.1 - 0.00062 19.9 16.9 0.0012 19.0 16.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RUS79232.1 - 0.0015 18.4 6.3 0.0021 17.9 6.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Imm41 PF15592.6 RUS79232.1 - 0.0033 17.8 0.0 0.0072 16.7 0.0 1.7 1 1 0 1 1 1 1 Immunity protein 41 Prok-RING_4 PF14447.6 RUS79232.1 - 0.0062 16.4 14.1 0.0095 15.8 14.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS79232.1 - 0.012 15.6 10.8 0.012 15.6 10.8 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 RUS79232.1 - 0.013 15.6 9.8 0.021 15.0 9.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 RUS79232.1 - 0.015 15.2 15.7 0.2 11.7 16.4 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 RUS79232.1 - 0.029 14.2 14.7 0.13 12.1 14.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Evr1_Alr PF04777.13 RUS79232.1 - 0.13 12.8 4.0 2 9.0 0.1 2.4 1 1 0 2 2 2 0 Erv1 / Alr family zf-RING_2 PF13639.6 RUS79232.1 - 0.15 12.4 16.6 0.22 11.9 16.6 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_5 PF17121.5 RUS79232.1 - 0.97 9.4 12.9 2.5 8.0 9.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 RUS79232.1 - 2.8 8.2 12.8 24 5.1 12.7 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger Rad1 PF02144.16 RUS79233.1 - 1.4e-78 263.8 4.9 1.6e-78 263.6 4.9 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 RUS79233.1 - 0.052 13.7 0.5 0.12 12.6 0.1 1.7 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain DUF2846 PF11008.8 RUS79233.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) p6 PF17548.2 RUS79234.1 - 0.027 14.4 0.1 0.085 12.8 0.0 1.8 1 1 1 2 2 2 0 Histone-like Protein p6 RAG1_imp_bd PF12560.8 RUS79234.1 - 0.037 13.6 1.1 0.05 13.1 1.1 1.3 1 1 0 1 1 1 0 RAG1 importin binding CaMBD PF02888.16 RUS79234.1 - 0.041 14.1 0.9 0.06 13.5 0.9 1.4 1 0 0 1 1 1 0 Calmodulin binding domain HeH PF12949.7 RUS79234.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 HeH/LEM domain PAN_1 PF00024.26 RUS79236.1 - 0.0055 16.7 1.6 0.011 15.7 0.3 2.0 2 0 0 2 2 2 1 PAN domain PRKCSH_1 PF13015.6 RUS79236.1 - 0.16 11.6 0.0 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein PAN_4 PF14295.6 RUS79236.1 - 0.24 11.3 2.8 0.59 10.1 0.3 2.4 2 0 0 2 2 2 0 PAN domain COX16 PF14138.6 RUS79237.1 - 5.7e-20 71.6 0.1 9.1e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RecA PF00154.21 RUS79237.1 - 0.072 12.5 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF765 PF05570.11 RUS79238.1 - 0.2 11.9 1.4 91 3.4 0.0 3.2 3 0 0 3 3 3 0 Circovirus protein of unknown function (DUF765) Cyto_heme_lyase PF01265.17 RUS79238.1 - 0.29 10.7 5.8 0.41 10.2 5.8 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase FOG_N PF15888.5 RUS79238.1 - 0.35 11.3 10.3 4.5 7.7 0.5 3.3 2 1 1 3 3 3 0 Folded gastrulation N-terminus YwpF PF14183.6 RUS79238.1 - 0.47 10.5 3.5 5.4 7.0 0.0 2.8 2 1 0 3 3 3 0 YwpF-like protein Costars PF14705.6 RUS79239.1 - 1.4e-29 102.1 0.0 2.5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Costars Synuclein PF01387.17 RUS79240.1 - 0.27 11.4 6.6 23 5.2 6.6 2.2 1 1 0 1 1 1 0 Synuclein PilX_N PF14341.6 RUS79240.1 - 0.32 11.0 42.2 55 3.8 0.2 11.1 1 1 9 10 10 10 0 PilX N-terminal RFX_DNA_binding PF02257.15 RUS79241.1 - 8.8e-32 109.6 0.1 2.4e-31 108.2 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain SPT16 PF08644.11 RUS79242.1 - 0.0011 19.1 0.2 0.0019 18.4 0.2 1.3 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_S49_N PF08496.10 RUS79242.1 - 0.043 13.9 0.6 0.065 13.3 0.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tetraspanin PF00335.20 RUS79242.1 - 0.085 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Connexin PF00029.19 RUS79242.1 - 0.099 12.4 0.7 0.14 11.9 0.7 1.1 1 0 0 1 1 1 0 Connexin DUF4446 PF14584.6 RUS79242.1 - 0.23 11.4 1.3 0.32 10.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF5347 PF17282.2 RUS79242.1 - 0.34 11.2 2.4 0.59 10.5 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5347) DUF4522 PF15022.6 RUS79243.1 - 0.26 11.6 6.2 4 7.7 1.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4522) DUF4573 PF15140.6 RUS79244.1 - 3e-06 27.2 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Nodulin_late PF07127.11 RUS79244.1 - 0.22 11.9 13.5 0.32 11.3 0.5 3.3 3 0 0 3 3 3 0 Late nodulin protein HCO3_cotransp PF00955.21 RUS79245.1 - 5.8e-161 536.8 0.6 7.4e-161 536.4 0.6 1.0 1 0 0 1 1 1 1 HCO3- transporter family Sulfate_transp PF00916.20 RUS79245.1 - 0.0014 17.5 3.3 0.072 11.8 0.1 2.4 2 0 0 2 2 2 2 Sulfate permease family OCC1 PF15506.6 RUS79247.1 - 4.5e-06 26.7 0.1 1.5e+02 2.5 0.0 9.4 4 2 8 12 12 12 0 OCC1 family MxiM PF11441.8 RUS79247.1 - 0.0035 17.6 22.4 77 3.6 0.1 9.5 1 1 11 12 12 12 1 Pilot protein MxiM Knl1_RWD_C PF18210.1 RUS79248.1 - 7.1e-11 42.5 21.4 1 9.9 0.4 6.8 1 1 5 7 7 7 7 Knl1 RWD C-terminal domain HTH_24 PF13412.6 RUS79248.1 - 6.6e-07 28.8 79.9 33 4.2 0.1 20.9 1 1 21 22 22 22 21 Winged helix-turn-helix DNA-binding SprT-like PF10263.9 RUS79248.1 - 0.11 12.3 15.8 1.8e+04 -7.2 15.8 5.7 1 1 0 1 1 1 0 SprT-like family AIG1 PF04548.16 RUS79250.1 - 1.3e-43 148.8 0.2 1.3e-43 148.8 0.2 1.9 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS79250.1 - 4.7e-10 39.6 0.2 1.5e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 RUS79250.1 - 0.002 17.5 0.0 0.002 17.5 0.0 1.7 2 1 0 2 2 2 1 Septin HGTP_anticodon2 PF12745.7 RUS79250.1 - 0.0021 17.6 12.3 0.0035 16.9 12.3 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs SRPRB PF09439.10 RUS79250.1 - 0.034 13.6 0.1 0.034 13.6 0.1 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 RUS79250.1 - 0.073 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS79250.1 - 0.091 12.7 1.5 0.21 11.5 0.3 2.2 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 RUS79250.1 - 0.57 10.2 10.9 0.13 12.3 0.9 2.8 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 RUS79251.1 - 1e-45 155.7 0.2 1e-45 155.7 0.2 2.4 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS79251.1 - 1.9e-08 34.4 0.0 1.9e-08 34.4 0.0 2.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS79251.1 - 0.03 13.9 0.4 0.081 12.5 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 RUS79251.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 RUS79251.1 - 0.6 10.6 0.0 0.6 10.6 0.0 3.3 2 1 0 2 2 2 0 ABC transporter Mitofilin PF09731.9 RUS79251.1 - 3.5 6.3 33.0 5.8 5.6 33.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ALMT PF11744.8 RUS79251.1 - 6 5.6 18.6 8.9 5.0 18.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2407_C PF13373.6 RUS79251.1 - 8.1 6.6 16.1 0.56 10.4 9.5 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain RsgA_GTPase PF03193.16 RUS79251.1 - 9.2 6.1 7.0 0.85 9.5 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase TMEM132D_N PF15705.5 RUS79253.1 - 0.16 11.8 3.3 0.5 10.2 3.3 1.9 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term SyrA PF11089.8 RUS79253.1 - 2.9 8.0 25.2 9.8 6.3 0.8 5.5 2 1 4 7 7 7 0 Exopolysaccharide production repressor UPRTase PF14681.6 RUS79254.1 - 1.3e-72 243.7 0.0 2e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 RUS79254.1 - 4.8e-60 202.7 0.0 6.9e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 RUS79254.1 - 9.1e-07 28.9 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 RUS79254.1 - 6.6e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS79254.1 - 0.0006 20.0 0.0 0.0027 17.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 RUS79254.1 - 0.0007 20.0 0.4 0.0053 17.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 RUS79254.1 - 0.011 15.4 0.0 0.068 12.8 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase dNK PF01712.19 RUS79254.1 - 0.015 15.2 0.0 0.076 12.9 0.0 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase 6PF2K PF01591.18 RUS79254.1 - 0.035 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 RUS79254.1 - 0.14 12.1 0.0 2.2 8.2 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase SE PF08491.10 RUS79256.1 - 4.5e-108 360.5 0.1 7.2e-108 359.8 0.1 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 RUS79256.1 - 1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RUS79256.1 - 4.5e-08 33.1 0.1 3.3e-05 23.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 RUS79256.1 - 3.4e-06 26.4 0.0 4.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 RUS79256.1 - 1.3e-05 25.3 0.2 2.9e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RUS79256.1 - 5.2e-05 22.5 1.2 0.0007 18.8 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS79256.1 - 0.00015 21.1 1.2 0.00036 19.8 0.3 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS79256.1 - 0.00023 21.7 0.5 0.00068 20.1 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RUS79256.1 - 0.0012 17.8 1.0 0.15 10.9 0.3 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 RUS79256.1 - 0.0035 16.8 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS79256.1 - 0.005 16.1 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 RUS79256.1 - 0.0058 16.9 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 RUS79256.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 RUS79256.1 - 0.013 14.2 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 RUS79256.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 RUS79256.1 - 0.022 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RUS79256.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 RUS79256.1 - 0.042 12.9 0.2 0.082 11.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 RUS79256.1 - 0.063 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 RUS79256.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 RUS79256.1 - 0.15 12.7 0.2 0.56 10.8 0.1 2.1 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent PRA1 PF03208.19 RUS79256.1 - 8.6 6.0 7.7 11 5.6 1.4 2.9 2 1 1 3 3 3 0 PRA1 family protein Pentapeptide_3 PF13576.6 RUS79257.1 - 0.00018 21.6 23.3 1.8e+04 -4.6 23.3 4.8 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Phage_SSB PF16773.5 RUS79257.1 - 0.047 13.7 3.4 18 5.5 0.1 3.5 1 1 3 4 4 4 0 Lactococcus phage single-stranded DNA binding protein DUF4900 PF16241.5 RUS79257.1 - 2.1 8.7 18.7 12 6.3 4.9 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4900) ISK_Channel PF02060.15 RUS79258.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel E1-N PF14463.6 RUS79258.1 - 0.016 15.1 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 E1 N-terminal domain RCR PF12273.8 RUS79258.1 - 0.045 14.4 0.0 0.061 14.0 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ras PF00071.22 RUS79259.1 - 1.6e-32 112.3 1.4 4.4e-20 71.9 0.1 2.2 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RUS79259.1 - 2.1e-15 57.0 1.5 2.6e-14 53.5 0.5 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS79259.1 - 5.9e-05 22.6 0.3 0.21 11.0 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 RUS79259.1 - 0.013 15.5 0.2 0.028 14.4 0.2 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 RUS79259.1 - 0.014 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 RUS79259.1 - 0.019 14.5 0.5 0.58 9.7 0.5 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-RING_2 PF13639.6 RUS79260.1 - 1.5e-12 47.6 6.8 2.3e-12 47.0 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS79260.1 - 5.3e-11 42.1 3.4 5.3e-11 42.1 3.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RUS79260.1 - 1.9e-09 37.4 3.0 3.8e-09 36.4 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS79260.1 - 1.2e-08 34.7 6.9 1.9e-08 34.0 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS79260.1 - 3e-07 30.2 6.2 4.9e-07 29.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79260.1 - 2.1e-06 27.5 3.3 3.3e-06 26.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS79260.1 - 2.3e-06 27.8 9.1 6e-05 23.3 9.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS79260.1 - 1.1e-05 25.3 5.1 1.2e-05 25.2 3.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS79260.1 - 0.00072 19.4 1.4 0.0018 18.1 1.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 RUS79260.1 - 0.023 14.5 3.0 0.044 13.6 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 RUS79260.1 - 0.035 14.2 2.9 0.1 12.7 2.9 1.8 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 RUS79260.1 - 0.091 12.4 5.8 0.19 11.4 5.8 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RUS79260.1 - 0.16 12.2 9.2 3.4 7.9 9.2 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 RUS79260.1 - 0.2 11.7 6.0 3.3 7.8 5.8 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RUS79260.1 - 0.2 11.8 7.0 0.41 10.8 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 RUS79260.1 - 0.71 10.0 4.5 1.6 8.9 4.5 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 RUS79260.1 - 9 6.3 7.6 6.3 6.8 3.5 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Aquarius_N PF16399.5 RUS79261.1 - 0 1020.1 4.8 0 1019.8 4.8 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 RUS79261.1 - 4.3e-29 102.1 0.0 1.3e-28 100.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RUS79261.1 - 6.4e-26 91.2 0.0 2e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS79261.1 - 4.3e-09 36.8 0.2 5.1e-08 33.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS79261.1 - 4.4e-07 29.8 0.0 0.00049 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 RUS79261.1 - 7.1e-06 26.1 0.0 2.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 RUS79261.1 - 0.00017 21.2 0.0 0.00052 19.6 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Parvo_NS1 PF01057.17 RUS79261.1 - 0.00058 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DEAD PF00270.29 RUS79261.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecA PF00154.21 RUS79261.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 RUS79261.1 - 0.0021 18.5 0.1 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 RUS79261.1 - 0.0049 16.2 0.2 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 RUS79261.1 - 0.0072 16.7 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 RUS79261.1 - 0.0089 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.15 RUS79261.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD_C_2 PF13538.6 RUS79261.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 RUS79261.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS79261.1 - 0.093 13.0 0.4 0.98 9.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 RUS79261.1 - 0.11 13.1 0.0 3.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RUS79261.1 - 0.15 11.4 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 RUS79261.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tfb5 PF06331.12 RUS79261.1 - 0.19 11.7 0.6 0.52 10.3 0.1 2.0 2 0 0 2 2 1 0 Transcription factor TFIIH complex subunit Tfb5 Metallothio_Cad PF07846.11 RUS79262.1 - 7.7e-12 45.1 81.0 8.4 6.6 0.9 16.1 15 1 1 16 16 16 15 Metallothionein family HTH_AraC PF00165.23 RUS79262.1 - 1.9e-09 37.4 11.9 1.7e+02 2.5 0.0 12.9 2 2 13 15 15 15 0 Bacterial regulatory helix-turn-helix proteins, AraC family nos_propeller_2 PF18793.1 RUS79262.1 - 8.1e-05 22.9 0.0 29 5.1 0.0 5.9 1 1 11 12 12 12 1 Nitrous oxide reductase propeller repeat 2 Rad4 PF03835.15 RUS79262.1 - 0.24 11.1 11.4 94 2.7 0.1 6.4 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain NosD PF05048.13 RUS79263.1 - 5e-06 26.0 6.6 0.012 14.9 1.0 2.3 1 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) MORN PF02493.20 RUS79263.1 - 0.0017 18.1 0.7 6e+02 0.7 0.0 6.8 8 0 0 8 8 8 0 MORN repeat CcmH PF03918.14 RUS79263.1 - 0.002 17.4 0.0 98 2.2 0.0 4.9 1 1 7 8 8 8 0 Cytochrome C biogenesis protein SCRG1 PF15224.6 RUS79263.1 - 0.0043 17.1 4.5 67 3.7 0.1 4.5 1 1 6 7 7 7 0 Scrapie-responsive protein 1 DUF4528 PF15031.6 RUS79263.1 - 0.1 12.7 0.1 33 4.5 0.0 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4528) Pentapeptide_2 PF01469.18 RUS79264.1 - 5e-13 48.7 0.0 3 7.8 0.0 6.2 1 1 9 10 10 10 10 Pentapeptide repeats (8 copies) PMG PF05287.12 RUS79265.1 - 2.6e-05 24.3 53.9 4.7e-05 23.5 53.9 1.4 1 1 0 1 1 1 1 PMG protein Keratin_B2_2 PF13885.6 RUS79265.1 - 0.054 13.5 97.5 2.6 8.1 25.3 4.2 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein TraB PF01963.17 RUS79266.1 - 4.4e-36 125.1 0.0 5.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 TraB family Linker_histone PF00538.19 RUS79269.1 - 1.3e-28 99.2 1.3 1.3e-28 99.2 1.3 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family POLO_box PF00659.18 RUS79270.1 - 0.0051 17.0 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 POLO box duplicated region Pkinase PF00069.25 RUS79271.1 - 1.8e-71 240.6 0.0 2.7e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79271.1 - 3.6e-44 151.0 0.0 6.4e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 RUS79271.1 - 4.5e-36 123.9 0.1 1.8e-35 121.9 0.1 2.2 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 RUS79271.1 - 3.2e-35 120.5 0.1 9e-35 119.1 0.1 1.8 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Pkinase_fungal PF17667.1 RUS79271.1 - 6.4e-07 28.5 0.0 2.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS79271.1 - 3.7e-05 23.2 0.0 0.00067 19.1 0.0 2.4 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS79271.1 - 0.00023 20.8 0.8 0.0013 18.4 0.8 1.9 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 RUS79271.1 - 0.0053 16.1 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS79271.1 - 0.0067 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family POLO_box PF00659.18 RUS79271.1 - 0.014 15.6 0.1 0.23 11.7 0.0 3.1 3 1 0 3 3 3 0 POLO box duplicated region Haspin_kinase PF12330.8 RUS79271.1 - 0.018 14.0 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HSP70 PF00012.20 RUS79272.1 - 5.4e-170 566.5 11.8 4.3e-159 530.5 1.4 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 RUS79272.1 - 5.3e-10 38.6 0.0 9.7e-10 37.8 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DUF3137 PF11335.8 RUS79272.1 - 0.035 14.1 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) TEX19 PF15553.6 RUS79272.1 - 1.8 8.5 6.2 0.98 9.4 2.7 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 YABBY PF04690.13 RUS79272.1 - 8.6 6.9 7.6 7.1 7.2 4.9 2.2 1 1 1 2 2 2 0 YABBY protein UPF0016 PF01169.19 RUS79273.1 - 8.8e-39 131.7 19.2 1.6e-19 70.0 12.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 RUS79273.1 - 0.0036 17.1 0.6 0.0036 17.1 0.6 2.3 2 1 0 2 2 2 1 Putative manganese efflux pump Dpy19 PF10034.9 RUS79273.1 - 0.074 11.2 0.3 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Phage_holin_3_6 PF07332.11 RUS79273.1 - 3.3 7.8 11.6 0.062 13.3 3.6 2.1 2 2 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III OTU PF02338.19 RUS79274.1 - 0.0033 17.9 0.0 0.0093 16.5 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease Prok-RING_1 PF14446.6 RUS79274.1 - 1.9 8.5 10.3 0.065 13.2 3.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Presenilin PF01080.17 RUS79274.1 - 5.7 5.6 5.4 10 4.8 5.4 1.3 1 0 0 1 1 1 0 Presenilin 7tm_1 PF00001.21 RUS79275.1 - 1e-13 51.2 20.9 1.4e-13 50.8 20.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS79275.1 - 1e-07 31.6 15.2 1.4e-07 31.1 15.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS79277.1 - 3.8e-53 180.5 9.2 5e-53 180.1 9.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS79277.1 - 1.4e-07 31.1 14.4 1.8e-05 24.3 7.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS79277.1 - 3.3e-06 27.1 8.8 7e-06 26.0 8.8 1.7 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS79277.1 - 2.2e-05 24.2 10.3 2.2e-05 24.2 10.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Abhydrolase_6 PF12697.7 RUS79278.1 - 5e-07 30.5 0.0 6.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 RUS79279.1 - 9.6e-20 72.1 0.2 1.3e-19 71.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS79279.1 - 4.6e-09 36.3 0.0 5.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS79279.1 - 4.9e-08 32.5 0.0 7.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RUS79279.1 - 1.4e-05 25.4 0.0 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.13 RUS79279.1 - 4e-05 23.6 0.4 0.00019 21.4 0.3 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 RUS79279.1 - 0.00068 19.4 0.3 0.0014 18.4 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 RUS79279.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 RUS79279.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 RUS79279.1 - 0.014 15.3 0.1 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 RUS79279.1 - 0.19 10.6 0.2 0.4 9.6 0.2 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme FixS PF03597.15 RUS79279.1 - 4.1 7.2 0.0 4.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type bZIP_2 PF07716.15 RUS79281.1 - 2.2e-16 59.6 12.1 3.4e-16 59.0 8.7 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 RUS79281.1 - 8.1e-06 25.9 10.3 1.2e-05 25.3 10.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 RUS79281.1 - 0.0044 16.9 1.2 0.0066 16.3 1.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 RUS79281.1 - 0.0058 16.7 0.2 0.0076 16.3 0.2 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion bZIP_Maf PF03131.17 RUS79281.1 - 0.0058 17.1 5.6 0.011 16.2 5.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Seadorna_VP6 PF07407.11 RUS79281.1 - 0.0064 15.5 0.1 0.0082 15.1 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP6 protein DivIC PF04977.15 RUS79281.1 - 0.018 14.8 0.2 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator SOGA PF11365.8 RUS79281.1 - 0.025 15.7 0.4 0.049 14.8 0.4 1.5 1 0 0 1 1 1 0 Protein SOGA VGPC1_C PF16799.5 RUS79281.1 - 0.085 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ZapB PF06005.12 RUS79281.1 - 0.093 13.2 1.0 0.17 12.4 1.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Mto2_bdg PF12808.7 RUS79281.1 - 0.15 12.4 3.6 0.25 11.7 2.7 1.8 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ank_2 PF12796.7 RUS79282.1 - 1.8e-32 111.8 0.0 4.6e-12 46.4 0.1 3.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS79282.1 - 3.7e-27 94.3 0.1 5e-10 39.7 0.0 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS79282.1 - 2.4e-23 81.9 0.1 1.4e-12 47.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79282.1 - 3.8e-21 72.9 0.5 9.9e-06 25.5 0.1 7.6 7 1 1 8 8 8 3 Ankyrin repeat Ank PF00023.30 RUS79282.1 - 1.2e-19 69.8 0.2 2.1e-05 24.8 0.0 6.1 5 1 0 5 5 5 3 Ankyrin repeat SOCS_box PF07525.16 RUS79282.1 - 1.5e-07 31.7 0.2 3.8e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 SOCS box Uds1 PF15456.6 RUS79283.1 - 0.01 16.0 3.0 0.021 15.0 3.0 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Utp12 PF04003.12 RUS79283.1 - 2.2 8.6 6.4 0.62 10.4 0.3 3.0 3 1 0 3 3 3 0 Dip2/Utp12 Family DUF3105 PF11303.8 RUS79284.1 - 1.6e-28 99.4 0.0 2.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) PS_Dcarbxylase PF02666.15 RUS79285.1 - 9.1e-46 155.9 0.0 1.1e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RabGAP-TBC PF00566.18 RUS79286.1 - 7.5e-52 176.1 0.0 1.4e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PTS_2-RNA PF01885.16 RUS79287.1 - 7.9e-11 42.3 0.1 1.3e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family LRR_4 PF12799.7 RUS79287.1 - 0.0072 16.7 3.5 1.2 9.7 0.8 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) NOA36 PF06524.12 RUS79287.1 - 0.012 15.0 5.2 0.021 14.1 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein RXLR_WY PF18634.1 RUS79287.1 - 3.5 7.6 8.2 5.8 6.9 0.1 4.0 4 0 0 4 4 4 0 RXLR phytopathogen effector protein WY-domain 2OG-FeII_Oxy_2 PF13532.6 RUS79288.1 - 5.1e-25 88.8 0.0 1.1e-24 87.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 RUS79289.1 - 6e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS79289.1 - 3.4e-10 39.3 0.4 5.6e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RUS79289.1 - 5.1e-10 39.3 0.0 8.9e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RUS79289.1 - 3.6e-09 37.0 0.1 1.6e-05 25.3 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS79289.1 - 1.4e-07 31.6 0.0 0.00042 20.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 RUS79290.1 - 5.5e-09 35.4 40.0 0.00015 20.8 22.1 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS79290.1 - 1.2e-07 31.0 24.1 0.00036 19.5 12.0 3.3 2 2 2 4 4 4 3 Sugar (and other) transporter MFS_1_like PF12832.7 RUS79290.1 - 0.1 11.4 9.3 0.5 9.2 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family p450 PF00067.22 RUS79291.1 - 1.8e-47 162.2 0.0 8.5e-35 120.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 RUS79292.1 - 1.5e-09 37.1 0.0 1.7e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LisH_2 PF16045.5 RUS79294.1 - 6.9e-15 53.8 1.0 6.9e-15 53.8 1.0 1.8 2 0 0 2 2 2 1 LisH FOP_dimer PF09398.10 RUS79294.1 - 0.0051 17.0 3.3 0.021 15.1 0.0 3.4 3 0 0 3 3 3 1 FOP N terminal dimerisation domain AA_permease_2 PF13520.6 RUS79295.1 - 4.3e-62 210.3 47.8 5.2e-62 210.1 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS79295.1 - 2.7e-28 98.8 41.7 3.5e-28 98.4 41.7 1.2 1 0 0 1 1 1 1 Amino acid permease Myc_target_1 PF15179.6 RUS79295.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 Podoplanin PF05808.11 RUS79295.1 - 7.4 6.7 6.6 0.28 11.3 0.5 1.8 2 0 0 2 2 2 0 Podoplanin Drf_FH1 PF06346.12 RUS79296.1 - 0.18 11.5 20.0 0.28 10.9 20.0 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Beach PF02138.18 RUS79297.1 - 7e-124 412.7 1.9 1.1e-123 412.0 1.9 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 RUS79297.1 - 5.6e-110 367.0 0.2 1.4e-109 365.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 RUS79297.1 - 8.5e-74 246.8 9.6 2.4e-73 245.3 9.6 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 RUS79297.1 - 2.7e-28 98.0 0.0 1.2e-27 96.0 0.0 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 RUS79297.1 - 5.1e-10 39.8 5.0 0.0053 17.6 0.2 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 RUS79297.1 - 0.00013 21.3 0.1 0.0003 20.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DNA_pol_phi PF04931.13 RUS79298.1 - 0.00053 18.2 33.7 0.00053 18.2 33.7 1.7 2 0 0 2 2 2 1 DNA polymerase phi DUF2615 PF11027.8 RUS79298.1 - 0.03 14.5 14.2 0.29 11.3 2.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Nop14 PF04147.12 RUS79298.1 - 0.055 11.7 22.2 0.072 11.3 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS79298.1 - 0.056 12.8 12.2 0.095 12.1 12.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 RUS79298.1 - 0.14 11.5 14.2 0.18 11.1 14.2 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 RUS79298.1 - 0.24 9.9 27.1 0.34 9.4 27.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2946 PF11162.8 RUS79298.1 - 1.6 9.4 4.3 4.3 8.0 4.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Mpp10 PF04006.12 RUS79298.1 - 6.6 5.0 20.3 8.6 4.7 20.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Mab-21 PF03281.14 RUS79299.1 - 1.9e-100 336.0 0.0 2.3e-100 335.7 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein EMP70 PF02990.16 RUS79300.1 - 3.5e-90 303.1 28.8 3.5e-90 303.1 28.8 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 Radical_SAM_C PF16199.5 RUS79301.1 - 1e-33 115.2 0.0 3e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 RUS79301.1 - 1.9e-22 80.4 0.4 4.1e-21 76.1 0.0 2.8 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 RUS79301.1 - 2.8e-10 40.5 0.1 4.9e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS79301.1 - 5.7e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS79301.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PHD PF00628.29 RUS79302.1 - 5.4e-11 42.2 32.0 1.1e-05 25.2 10.5 2.7 3 0 0 3 3 2 2 PHD-finger C1_1 PF00130.22 RUS79302.1 - 5.2e-06 26.3 10.0 0.00067 19.5 1.5 3.9 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DBD_Tnp_Hermes PF10683.9 RUS79302.1 - 5.6e-05 22.7 0.5 0.51 10.1 0.1 2.6 2 0 0 2 2 2 2 Hermes transposase DNA-binding domain DZR PF12773.7 RUS79302.1 - 0.0089 16.0 7.8 0.88 9.7 0.8 2.7 2 0 0 2 2 2 2 Double zinc ribbon Vps36-NZF-N PF16988.5 RUS79302.1 - 0.014 14.8 0.4 7.9 6.0 0.0 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FYVE PF01363.21 RUS79302.1 - 0.021 15.0 18.7 0.29 11.3 4.2 2.5 2 1 0 2 2 2 0 FYVE zinc finger PHD_3 PF13922.6 RUS79302.1 - 0.022 15.1 7.7 1.5 9.3 1.0 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zinc-ribbons_6 PF07191.12 RUS79302.1 - 0.084 12.9 12.2 0.58 10.2 1.0 2.7 2 2 0 2 2 2 0 zinc-ribbons DHHC PF01529.20 RUS79302.1 - 0.086 12.9 3.3 7.6 6.6 0.3 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DNA_RNApol_7kD PF03604.13 RUS79302.1 - 0.23 11.2 13.2 2.5 7.8 2.8 2.8 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_2 PF03107.16 RUS79302.1 - 1.1 9.6 19.5 0.35 11.2 0.4 3.9 4 0 0 4 4 4 0 C1 domain zf-PHD-like PF15446.6 RUS79302.1 - 3.8 7.1 15.7 3.9 7.1 3.4 2.8 2 2 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-Sec23_Sec24 PF04810.15 RUS79302.1 - 4.3 7.5 9.5 22 5.2 1.4 3.3 2 2 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.6 RUS79302.1 - 6 7.3 20.3 6.2 7.2 5.1 2.9 2 2 0 2 2 2 0 Ring finger domain OrfB_Zn_ribbon PF07282.11 RUS79302.1 - 6.5 6.8 22.0 0.47 10.4 2.4 3.0 4 0 0 4 4 2 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 RUS79302.1 - 9 6.3 25.9 0.81 9.7 4.8 2.9 2 2 0 2 2 2 0 Prokaryotic RING finger family 1 Profilin PF00235.19 RUS79303.1 - 1e-07 32.3 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Profilin Methyltransf_21 PF05050.12 RUS79304.1 - 6e-07 29.7 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_11 PF08241.12 RUS79304.1 - 0.0096 16.6 0.1 0.032 14.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS79304.1 - 0.039 14.7 0.0 0.15 12.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RUS79304.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA_2 PF13911.6 RUS79305.1 - 8.2e-17 61.4 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 RUS79305.1 - 0.00097 19.1 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 RUS79305.1 - 0.0076 15.8 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Redoxin PF08534.10 RUS79305.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Redoxin Ldl_recept_a PF00057.18 RUS79306.1 - 1.3e-72 239.7 166.8 5.2e-12 45.8 13.8 9.1 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 RUS79306.1 - 2.9e-33 114.1 5.6 1.2e-11 44.9 0.2 5.5 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 RUS79306.1 - 1.2e-08 35.1 28.5 1e-06 28.9 4.2 7.9 6 2 1 7 7 7 3 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 RUS79306.1 - 2.2e-08 33.7 0.0 6.2e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) SGL PF08450.12 RUS79306.1 - 0.00018 21.2 0.7 0.9 9.1 0.0 3.2 1 1 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region TMEM154 PF15102.6 RUS79306.1 - 0.032 14.1 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 RUS79306.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RRM_1 PF00076.22 RUS79307.1 - 1.5e-13 50.3 0.0 6e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 RUS79307.1 - 9.6e-08 31.6 1.1 2.7e-07 30.2 0.8 2.0 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.6 RUS79307.1 - 6.6e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tektin PF03148.14 RUS79308.1 - 2.7e-144 480.6 40.4 3.1e-144 480.4 40.4 1.0 1 0 0 1 1 1 1 Tektin family COG2 PF06148.11 RUS79308.1 - 0.34 11.0 18.3 0.31 11.1 2.4 4.0 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Rz1 PF06085.11 RUS79308.1 - 1.3 8.8 4.0 4.1 7.2 4.0 1.8 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor CdvA PF18822.1 RUS79308.1 - 1.5 8.6 26.3 0.12 12.2 4.0 4.3 4 0 0 4 4 4 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 RUS79308.1 - 2.3 8.2 18.4 0.13 12.3 2.8 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 RUS79308.1 - 2.8 8.0 21.4 0.29 11.2 3.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) H-kinase_dim PF02895.14 RUS79308.1 - 7.9 7.0 13.1 39 4.7 7.9 3.7 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Forkhead PF00250.18 RUS79309.1 - 3.5e-40 136.1 0.2 6.1e-40 135.4 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 RUS79309.1 - 8.7e-08 32.4 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 RUS79309.1 - 0.086 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 linker histone H1 and H5 family WD40 PF00400.32 RUS79310.1 - 7e-34 115.3 8.9 0.00093 20.0 0.1 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79310.1 - 7.1e-05 23.0 5.5 11 6.4 0.0 6.7 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS79310.1 - 7.9e-05 22.1 2.2 0.97 8.7 0.0 4.2 3 1 2 5 5 5 2 WD40-like domain DUF1367 PF07105.11 RUS79311.1 - 0.064 12.9 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) APG12 PF04110.13 RUS79312.1 - 3.7e-32 110.6 0.0 4.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 RUS79312.1 - 1.6e-06 28.3 0.0 1.9e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like LCD1 PF09798.9 RUS79312.1 - 0.32 9.5 2.2 0.37 9.3 2.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Snf7 PF03357.21 RUS79313.1 - 8.5e-38 129.6 17.4 1.1e-37 129.3 17.4 1.1 1 0 0 1 1 1 1 Snf7 PIG-X PF08320.12 RUS79314.1 - 1.6e-37 129.5 0.2 2e-37 129.2 0.2 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 p450 PF00067.22 RUS79317.1 - 8.3e-107 357.8 0.0 1e-106 357.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IRS PF02174.17 RUS79318.1 - 1.2e-12 47.6 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 RUS79318.1 - 0.0062 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 RUS79320.1 - 1e-70 238.2 0.0 1.5e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79320.1 - 1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS79320.1 - 3e-08 33.3 0.0 6.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS79320.1 - 6.5e-05 22.4 0.4 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS79320.1 - 9.3e-05 21.5 0.1 9.3e-05 21.5 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 RUS79320.1 - 0.0005 20.1 0.1 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RUS79320.1 - 0.0028 17.3 0.0 0.0068 16.0 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase MRP PF09387.10 RUS79320.1 - 0.0042 17.1 2.5 0.0084 16.1 2.5 1.5 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP RIO1 PF01163.22 RUS79320.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family PHD PF00628.29 RUS79321.1 - 8e-25 86.5 41.9 6.2e-09 35.6 7.3 3.5 3 0 0 3 3 3 3 PHD-finger Bromodomain PF00439.25 RUS79321.1 - 1.5e-24 85.9 0.2 3.4e-24 84.7 0.2 1.7 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 RUS79321.1 - 7.4e-16 58.2 1.7 7.4e-16 58.2 1.7 2.2 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 RUS79321.1 - 7.4e-06 26.4 2.2 7.4e-06 26.4 2.2 5.7 4 2 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 RUS79321.1 - 0.0005 19.5 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 RUS79321.1 - 0.34 10.5 25.0 1.1 8.9 2.5 3.6 3 0 0 3 3 3 0 PHD-finger Thioredoxin_16 PF18569.1 RUS79322.1 - 1.5e-20 73.1 0.4 4.7e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain GST_C_2 PF13410.6 RUS79322.1 - 0.0059 16.6 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd PF16780.5 RUS79322.1 - 0.06 13.1 5.9 0.28 10.9 3.5 2.5 1 1 1 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain GST_C_3 PF14497.6 RUS79322.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OTU PF02338.19 RUS79324.1 - 6.9e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DAGK_acc PF00609.19 RUS79325.1 - 9.9e-48 162.5 0.0 1.6e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RUS79325.1 - 4.7e-24 84.4 0.0 7.8e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RUS79325.1 - 1.9e-08 34.0 14.4 2.5e-07 30.5 4.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TIMP PF00965.17 RUS79326.1 - 0.0013 18.6 0.5 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Tissue inhibitor of metalloproteinase SR-25 PF10500.9 RUS79326.1 - 1.4 8.5 7.2 2.5 7.7 7.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 RUS79326.1 - 2.9 8.3 11.8 0.19 12.0 5.1 2.4 3 0 0 3 3 3 0 Early growth response N-terminal domain Ank_4 PF13637.6 RUS79327.1 - 8.9e-56 185.6 3.9 2e-13 50.6 0.1 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS79327.1 - 2.9e-47 159.2 0.2 5.2e-20 71.8 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS79327.1 - 1.2e-39 133.9 1.8 1e-11 44.8 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS79327.1 - 4.2e-34 115.5 1.5 5.8e-06 26.5 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 RUS79327.1 - 4e-33 109.7 0.0 2.6e-05 24.3 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat La PF05383.17 RUS79328.1 - 1.1e-16 60.6 0.2 3.7e-16 58.9 0.2 2.0 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RUS79328.1 - 2.9e-16 59.0 0.0 2.9e-14 52.6 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS79328.1 - 1.7e-11 44.1 1.6 2.5e-11 43.5 1.6 4.5 6 0 0 6 6 6 2 RNA binding motif Med9 PF07544.13 RUS79329.1 - 4.8e-16 58.6 1.7 6.1e-16 58.3 1.7 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 BRE1 PF08647.11 RUS79329.1 - 0.0053 16.8 0.8 0.0083 16.2 0.6 1.4 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase Sigma70_ner PF04546.13 RUS79329.1 - 0.03 14.2 0.4 0.037 13.9 0.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Tektin PF03148.14 RUS79329.1 - 0.033 12.9 2.3 0.038 12.8 2.3 1.1 1 0 0 1 1 1 0 Tektin family Gemin6 PF06372.12 RUS79330.1 - 1.1e-32 112.8 0.0 1.4e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Gemin6 protein DUF4564 PF15169.6 RUS79331.1 - 4e-25 88.6 0.0 5.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) CDC45 PF02724.14 RUS79331.1 - 0.58 8.4 3.3 0.86 7.8 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.28 RUS79332.1 - 2.9e-13 50.8 0.3 4.5e-13 50.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GPR_Gpa2_C PF11970.8 RUS79332.1 - 0.0009 19.3 1.0 0.0019 18.2 1.0 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4959 PF16323.5 RUS79332.1 - 0.1 13.0 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) Flo11 PF10182.9 RUS79333.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Flo11 domain BORCS8 PF10167.9 RUS79334.1 - 0.0021 18.0 5.4 18 5.3 0.0 4.6 1 1 4 5 5 5 4 BLOC-1-related complex sub-unit 8 7tm_1 PF00001.21 RUS79336.1 - 9.7e-06 25.1 12.9 2.5e-05 23.8 12.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS79336.1 - 0.031 13.9 19.6 0.41 10.2 16.4 3.1 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Prion_bPrPp PF11587.8 RUS79336.1 - 1.3 8.9 7.9 0.29 11.0 1.6 2.6 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal FMO-like PF00743.19 RUS79337.1 - 2.9e-182 606.8 0.0 3.5e-182 606.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS79337.1 - 6.3e-20 71.6 0.0 3.7e-14 52.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS79337.1 - 9.1e-10 38.2 0.0 1.5e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS79337.1 - 1.6e-09 37.3 6.2 1.7e-07 30.7 4.2 3.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RUS79337.1 - 5.8e-06 26.4 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS79337.1 - 0.0016 18.1 0.7 1.6 8.2 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 RUS79337.1 - 0.074 13.0 0.2 10 6.1 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Flavodoxin_1 PF00258.25 RUS79337.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Flavodoxin Peptidase_M17_N PF02789.17 RUS79337.1 - 0.15 11.9 0.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Thi4 PF01946.17 RUS79337.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 RUS79337.1 - 0.3 11.7 1.8 24 5.6 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ODR4-like PF14778.6 RUS79338.1 - 8.9e-87 291.4 0.0 1.2e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF835 PF05763.12 RUS79338.1 - 0.04 13.6 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF835) XhlA PF10779.9 RUS79338.1 - 0.65 10.2 0.1 0.65 10.2 0.1 2.7 3 0 0 3 3 3 0 Haemolysin XhlA WD40 PF00400.32 RUS79340.1 - 4.1e-15 55.9 4.3 0.00037 21.2 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79340.1 - 1.2e-10 41.5 0.0 0.0066 16.7 0.0 3.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS79340.1 - 0.048 13.0 0.0 17 4.6 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain MMS1_N PF10433.9 RUS79340.1 - 0.14 10.8 0.0 12 4.4 0.0 2.4 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Sep15_SelM PF08806.11 RUS79341.1 - 3.8e-18 65.4 1.2 6.4e-18 64.7 0.0 2.0 3 0 0 3 3 3 1 Sep15/SelM redox domain Glyco_hydro_47 PF01532.20 RUS79342.1 - 1.8e-161 538.1 0.0 2.1e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DERM PF14704.6 RUS79343.1 - 8.1e-39 133.5 0.2 9.5e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 Dermatopontin Cupin_8 PF13621.6 RUS79346.1 - 2.9e-19 69.8 0.1 2.1e-18 67.0 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RUS79346.1 - 0.0017 18.8 0.0 0.0099 16.3 0.1 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RUS79346.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 RUS79346.1 - 0.023 14.4 0.2 0.52 10.1 0.0 2.7 3 0 0 3 3 3 0 Cupin domain SOCS_box PF07525.16 RUS79347.1 - 7.4e-08 32.6 0.4 1.5e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 SOCS box Ank_5 PF13857.6 RUS79347.1 - 0.00038 20.7 0.1 0.0019 18.4 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79347.1 - 0.00045 20.5 0.1 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RUS79347.1 - 0.0014 19.2 0.1 0.0041 17.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS79347.1 - 0.011 16.1 0.9 0.033 14.6 0.9 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 RUS79347.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HC2 PF07382.11 RUS79347.1 - 0.082 13.0 4.6 0.032 14.3 2.1 1.5 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Macoilin PF09726.9 RUS79347.1 - 1.2 7.6 13.2 0.61 8.6 2.4 2.1 2 0 0 2 2 2 0 Macoilin family AhpC-TSA PF00578.21 RUS79348.1 - 5e-28 97.5 0.0 6.5e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS79348.1 - 3.8e-15 55.9 0.0 4.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RUS79348.1 - 2.7e-12 46.3 0.3 2.7e-12 46.3 0.3 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 RUS79348.1 - 0.0045 17.1 0.0 0.0086 16.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Syntaxin-6_N PF09177.11 RUS79349.1 - 0.28 11.7 4.3 0.38 11.3 2.1 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF883 PF05957.13 RUS79349.1 - 0.31 11.7 3.5 1.2 9.8 1.2 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) tRNA-synt_2b PF00587.25 RUS79350.1 - 0.0043 17.0 0.0 0.0051 16.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF423 PF04241.15 RUS79350.1 - 0.067 13.4 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Pro_isomerase PF00160.21 RUS79351.1 - 9.1e-50 169.0 0.0 1.1e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD bZIP_2 PF07716.15 RUS79354.1 - 2.5e-05 24.2 19.8 6.5e-05 22.9 19.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS79354.1 - 3.3e-05 23.9 17.5 7e-05 22.8 17.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS79354.1 - 0.022 15.3 20.3 0.039 14.5 19.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.11 RUS79354.1 - 1.7 8.7 10.9 3.5 7.7 10.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 RUS79355.1 - 6.8e-07 29.3 11.7 1.2e-06 28.5 11.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS79355.1 - 1.3e-05 25.1 10.7 3.1e-05 24.0 10.7 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS79355.1 - 2.1e-05 24.9 8.4 5.1e-05 23.7 8.4 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.9 RUS79355.1 - 0.00079 19.5 3.4 0.00079 19.5 3.4 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATF7IP_BD PF16788.5 RUS79355.1 - 0.33 11.0 8.2 0.04 14.0 2.3 2.2 2 1 0 2 2 2 0 ATF-interacting protein binding domain TPD52 PF04201.15 RUS79355.1 - 0.42 10.2 4.5 0.1 12.2 1.4 1.5 2 0 0 2 2 2 0 Tumour protein D52 family bZIP_1 PF00170.21 RUS79356.1 - 2.2e-07 30.8 10.0 2.2e-07 30.8 10.0 2.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 RUS79356.1 - 2.5e-06 27.5 9.5 4.9e-06 26.5 9.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS79356.1 - 0.0021 18.5 12.2 0.0042 17.6 10.9 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor Ferritin PF00210.24 RUS79356.1 - 0.043 13.7 0.5 0.075 13.0 0.5 1.3 1 0 0 1 1 1 0 Ferritin-like domain Phlebovirus_NSM PF07246.11 RUS79356.1 - 6.3 6.1 8.9 0.91 8.8 4.7 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M FapA PF03961.13 RUS79356.1 - 7.6 5.0 6.7 12 4.3 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PDZ_1 PF12812.7 RUS79360.1 - 1.3 9.1 3.9 14 5.8 0.1 3.3 2 1 2 4 4 4 0 PDZ-like domain bZIP_2 PF07716.15 RUS79361.1 - 2.9e-10 40.1 13.4 6.7e-10 38.9 13.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS79361.1 - 1.1e-08 35.0 13.0 2.1e-08 34.2 13.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS79361.1 - 4.3e-05 24.0 9.6 0.0001 22.7 9.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 RUS79361.1 - 0.021 15.3 2.0 0.053 14.0 2.0 1.7 1 0 0 1 1 1 0 Cell division protein ZapB FapA PF03961.13 RUS79361.1 - 0.16 10.6 1.8 0.23 10.0 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 RUS79361.1 - 1 9.2 4.1 2.6 7.9 4.1 1.7 1 0 0 1 1 1 0 Septum formation initiator UPF0449 PF15136.6 RUS79361.1 - 2.6 8.6 5.5 2.4 8.7 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Claudin_2 PF13903.6 RUS79362.1 - 1.6e-05 24.8 14.7 0.0018 18.1 11.1 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS79362.1 - 0.00014 21.8 10.4 0.00043 20.3 10.4 1.7 1 1 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 RUS79362.1 - 0.073 12.9 6.4 0.092 12.6 6.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family CbtA PF09490.10 RUS79362.1 - 0.22 11.3 7.8 0.3 10.8 6.9 1.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF4131 PF13567.6 RUS79362.1 - 1.9 8.1 5.7 1 9.0 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 RUS79362.1 - 5.7 7.5 15.2 1.4 9.4 4.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Asparaginase PF00710.20 RUS79364.1 - 1e-58 198.1 0.0 1.5e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 RUS79364.1 - 9.2e-17 61.3 0.0 1.9e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 RUS79364.1 - 5.7e-06 26.8 0.1 3.8e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS79364.1 - 2.6e-05 24.7 0.1 6.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS79364.1 - 0.00026 21.3 0.5 0.86 10.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RUS79364.1 - 0.00093 19.5 0.1 0.0027 18.0 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79364.1 - 0.028 14.9 0.1 13 6.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat ClpS PF02617.17 RUS79366.1 - 7.2e-23 80.2 0.3 2.2e-22 78.6 0.3 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 RUS79366.1 - 2.7e-21 75.5 9.7 2.7e-21 75.5 9.7 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) eIF-1a PF01176.19 RUS79367.1 - 3.9e-20 71.4 0.1 6.8e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sec10 PF07393.11 RUS79368.1 - 7.2e-125 418.1 8.2 2.7e-121 406.3 8.2 3.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 TelA PF05816.11 RUS79368.1 - 0.0014 17.8 0.2 0.0031 16.6 0.2 1.5 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Ax_dynein_light PF10211.9 RUS79368.1 - 0.01 15.8 2.5 0.026 14.5 2.5 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.12 RUS79368.1 - 0.015 15.4 0.1 0.043 13.9 0.1 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 RUS79368.1 - 0.021 14.7 2.5 0.06 13.2 1.9 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 RUS79368.1 - 0.034 14.3 0.8 0.1 12.7 0.8 1.8 1 0 0 1 1 1 0 Tropomyosin like CdvA PF18822.1 RUS79368.1 - 0.038 13.8 4.1 0.028 14.2 1.5 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF2458 PF10454.9 RUS79368.1 - 0.064 12.9 0.8 0.15 11.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF1664 PF07889.12 RUS79368.1 - 0.073 13.1 1.1 0.51 10.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 RUS79368.1 - 0.074 13.0 1.3 1.8 8.6 1.2 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Arc_PepC_II PF06847.11 RUS79368.1 - 0.19 12.2 1.4 4.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Prefoldin_2 PF01920.20 RUS79368.1 - 0.23 11.4 6.1 0.17 11.8 0.4 3.2 3 0 0 3 3 3 0 Prefoldin subunit DSPc PF00782.20 RUS79369.1 - 2.2e-41 140.8 0.0 3.8e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RUS79369.1 - 1.2e-10 41.8 0.0 1.4e-06 28.8 0.0 2.8 2 1 0 2 2 2 2 Rhodanese-like domain PTPlike_phytase PF14566.6 RUS79369.1 - 2e-06 28.0 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RUS79369.1 - 0.0013 18.3 0.1 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RUS79369.1 - 0.023 15.0 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 RUS79369.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Myotub-related PF06602.14 RUS79369.1 - 0.094 11.6 0.1 0.8 8.6 0.0 2.0 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Kelch_1 PF01344.25 RUS79370.1 - 2.6e-27 94.1 5.2 9.6e-11 41.1 0.1 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 RUS79370.1 - 4.7e-17 61.6 4.6 2e-08 34.2 0.0 3.4 1 1 2 3 3 3 3 Kelch motif Kelch_2 PF07646.15 RUS79370.1 - 2.2e-12 46.4 3.2 0.0032 17.4 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 RUS79370.1 - 5.7e-10 39.1 1.3 0.017 15.1 0.0 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS79370.1 - 5.2e-09 35.9 0.6 0.0028 17.6 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 RUS79370.1 - 4.8e-07 29.9 6.9 0.0048 17.1 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS79371.1 - 0.0019 17.7 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 RUS79371.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 RUS79371.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain zf-C3Hc3H PF13891.6 RUS79372.1 - 0.074 13.4 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain DUF2070 PF09843.9 RUS79372.1 - 5.3 5.2 11.0 5.6 5.1 11.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CCDC-167 PF15188.6 RUS79373.1 - 8.1e-17 61.4 1.7 1.1e-16 61.0 1.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 CCDC144C PF14915.6 RUS79373.1 - 0.0023 17.1 2.5 0.069 12.3 0.0 2.0 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region AAA_13 PF13166.6 RUS79373.1 - 0.024 13.3 0.8 0.028 13.1 0.8 1.0 1 0 0 1 1 1 0 AAA domain XhlA PF10779.9 RUS79373.1 - 0.025 14.8 10.7 0.75 10.0 10.4 2.2 1 1 0 1 1 1 0 Haemolysin XhlA U3_assoc_6 PF08640.11 RUS79373.1 - 0.03 14.4 3.6 0.046 13.8 3.6 1.2 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Mt_ATP-synt_D PF05873.12 RUS79373.1 - 0.042 13.7 2.3 0.05 13.5 1.5 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Phage_GP20 PF06810.11 RUS79373.1 - 0.063 13.1 3.7 0.092 12.5 3.4 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF3450 PF11932.8 RUS79373.1 - 0.08 12.2 4.0 0.36 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM196 PF15265.6 RUS79373.1 - 0.08 12.4 0.8 0.089 12.3 0.8 1.0 1 0 0 1 1 1 0 FAM196 family zf-C2H2_assoc2 PF16624.5 RUS79373.1 - 0.089 13.8 0.3 0.11 13.5 0.3 1.1 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger Mit_KHE1 PF10173.9 RUS79373.1 - 0.092 12.8 1.2 0.11 12.6 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ACCA PF03255.14 RUS79373.1 - 0.16 11.8 3.0 0.19 11.6 3.0 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FapA PF03961.13 RUS79373.1 - 0.18 10.4 1.4 0.21 10.1 1.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uds1 PF15456.6 RUS79373.1 - 0.38 10.9 6.1 2.1 8.6 1.2 2.1 1 1 1 2 2 2 0 Up-regulated During Septation Receptor_2B4 PF11465.8 RUS79373.1 - 0.4 10.9 2.3 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Prefoldin_2 PF01920.20 RUS79373.1 - 2 8.4 9.1 6.3 6.8 0.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit Fzo_mitofusin PF04799.13 RUS79373.1 - 4.8 6.7 10.3 2 7.9 1.3 2.6 1 1 0 2 2 2 0 fzo-like conserved region zf-Tim10_DDP PF02953.15 RUS79375.1 - 1.5e-16 59.8 5.0 2.1e-16 59.3 5.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Reprolysin_5 PF13688.6 RUS79376.1 - 6.5e-24 85.2 0.2 1.7e-23 83.8 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS79376.1 - 2.1e-20 73.5 0.5 4.5e-20 72.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS79376.1 - 1.2e-11 45.1 1.6 2.1e-11 44.4 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 RUS79376.1 - 6e-10 39.8 23.5 6e-10 39.8 23.5 2.7 2 0 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 RUS79376.1 - 7.7e-08 32.2 0.5 2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS79376.1 - 1.7e-06 28.1 0.1 1.7e-06 28.1 0.1 3.1 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease DUF3396 PF11876.8 RUS79376.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) Peptidase_M10 PF00413.24 RUS79376.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Matrixin Kelch_4 PF13418.6 RUS79377.1 - 1.4e-40 137.1 8.3 1e-08 35.0 0.0 6.6 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS79377.1 - 1.8e-29 101.2 4.5 0.00032 20.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS79377.1 - 1.2e-28 98.8 6.2 9.2e-06 25.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS79377.1 - 7e-25 86.3 4.7 2.6e-05 23.7 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS79377.1 - 4.9e-18 64.3 11.0 5.3e-05 23.0 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RUS79377.1 - 3.5e-17 62.0 9.9 0.041 14.2 0.0 6.9 6 1 1 7 7 7 5 Kelch motif DUF5427 PF10310.9 RUS79377.1 - 0.062 12.2 0.2 0.088 11.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Eclosion PF04736.12 RUS79379.1 - 6.7e-05 22.5 3.5 6.7e-05 22.5 3.5 2.1 2 1 0 2 2 2 1 Eclosion hormone LRR_6 PF13516.6 RUS79380.1 - 2.1e-16 58.5 26.8 0.0021 18.0 0.7 8.8 9 0 0 9 9 9 6 Leucine Rich repeat LRR_1 PF00560.33 RUS79380.1 - 7.3e-07 28.9 9.5 6 7.8 0.0 6.9 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 RUS79380.1 - 8.4e-06 26.0 17.1 0.0005 20.4 0.0 4.9 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS79380.1 - 0.002 17.9 20.7 0.039 13.7 3.1 6.3 5 2 0 5 5 5 2 Leucine rich repeat Tetraspanin PF00335.20 RUS79381.1 - 3.6e-15 56.3 1.4 3.6e-15 56.3 1.4 1.7 2 0 0 2 2 2 1 Tetraspanin family DUF3742 PF12553.8 RUS79381.1 - 0.2 11.8 0.4 0.66 10.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF2070 PF09843.9 RUS79381.1 - 1.1 7.5 6.2 1.7 6.8 6.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BP28CT PF08146.12 RUS79382.1 - 4.1e-38 130.7 3.3 4.1e-38 130.7 3.3 3.0 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 RUS79382.1 - 5.5e-24 84.8 1.8 5.5e-24 84.8 1.8 5.5 5 1 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 RUS79382.1 - 3.8e-05 24.1 0.8 0.24 11.9 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 RUS79382.1 - 0.001 19.4 4.5 0.15 12.5 0.0 6.0 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.22 RUS79382.1 - 0.0031 17.6 4.0 16 6.0 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat RabGAP-TBC PF00566.18 RUS79385.1 - 5.8e-55 186.3 0.8 6.1e-53 179.7 0.2 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH PF00169.29 RUS79385.1 - 2e-06 28.3 0.0 4.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 PH domain DivIC PF04977.15 RUS79385.1 - 0.0023 17.7 2.0 0.0023 17.7 2.0 3.6 3 1 1 4 4 4 1 Septum formation initiator PH_8 PF15409.6 RUS79385.1 - 0.004 17.4 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1244 PF06844.11 RUS79385.1 - 0.089 13.0 0.2 0.24 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Ntox1 PF15500.6 RUS79385.1 - 2.9 8.3 4.3 20 5.6 0.5 3.0 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 Sec34 PF04136.15 RUS79386.1 - 0.0061 16.5 3.2 0.0061 16.5 3.2 3.2 1 1 1 3 3 3 2 Sec34-like family XkdW PF09636.10 RUS79386.1 - 0.032 14.3 3.3 0.032 14.3 3.3 2.6 1 1 2 3 3 3 0 XkdW protein Pil1 PF13805.6 RUS79386.1 - 0.49 9.8 21.7 0.4 10.1 6.5 2.5 1 1 1 2 2 2 0 Eisosome component PIL1 DUF4201 PF13870.6 RUS79386.1 - 1.8 8.2 38.9 7 6.3 9.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DIRP PF06584.13 RUS79386.1 - 6 7.1 10.8 0.38 11.0 5.1 2.0 2 0 0 2 2 2 0 DIRP DUF812 PF05667.11 RUS79386.1 - 7 5.4 35.9 1.1 8.1 23.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FAM76 PF16046.5 RUS79386.1 - 7.5 5.8 33.2 0.39 10.0 15.4 2.4 1 1 1 2 2 2 0 FAM76 protein DUF2368 PF10166.9 RUS79388.1 - 1.5e-50 170.3 0.5 1.7e-50 170.1 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) EMC3_TMCO1 PF01956.16 RUS79388.1 - 4.3 7.0 8.1 5.5 6.7 7.7 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like eIF3_N PF09440.10 RUS79389.1 - 3.6e-49 166.6 5.4 9.9e-49 165.2 5.4 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 RUS79389.1 - 3.6e-20 72.4 1.3 7.8e-20 71.3 0.0 2.3 3 0 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 RUS79389.1 - 0.022 14.8 0.5 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 RUS79389.1 - 0.044 13.5 0.3 0.2 11.4 0.0 2.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 MMS19_N PF14500.6 RUS79389.1 - 0.049 13.2 0.7 0.1 12.1 0.3 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II WWE PF02825.20 RUS79390.1 - 8e-15 55.2 0.6 1.8e-14 54.1 0.6 1.6 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.6 RUS79390.1 - 3.1e-08 33.3 11.4 7.2e-08 32.2 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS79390.1 - 4.3e-05 23.8 12.3 0.0001 22.5 12.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS79390.1 - 0.00018 21.3 11.9 0.00018 21.3 11.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS79390.1 - 0.00038 20.5 12.2 0.0013 18.9 12.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS79390.1 - 0.00044 20.2 11.1 0.0015 18.5 11.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS79390.1 - 0.006 16.4 12.2 0.006 16.4 12.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS79390.1 - 0.033 14.2 12.1 0.033 14.2 12.1 2.0 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS79390.1 - 0.21 11.5 16.8 0.1 12.5 12.2 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C6H2 PF15801.5 RUS79390.1 - 9.9 6.6 14.3 41 4.6 5.6 2.8 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding G-patch_2 PF12656.7 RUS79391.1 - 1.2e-20 73.4 1.7 2.4e-20 72.4 0.1 2.4 2 0 0 2 2 2 1 G-patch domain KOW PF00467.29 RUS79391.1 - 6.2e-08 32.3 0.8 0.0043 17.0 0.1 2.7 2 0 0 2 2 2 2 KOW motif G-patch PF01585.23 RUS79391.1 - 2.3e-07 30.6 1.5 4.8e-07 29.6 1.5 1.5 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 RUS79391.1 - 4.2e-05 23.6 0.8 0.0025 17.9 0.0 3.2 2 1 1 3 3 3 1 KN17 SH3-like C-terminal domain Presenilin PF01080.17 RUS79391.1 - 3 6.5 7.4 4.8 5.9 7.4 1.3 1 0 0 1 1 1 0 Presenilin ArfGap PF01412.18 RUS79392.1 - 3e-32 111.2 0.9 3e-32 111.2 0.9 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf HECT PF00632.25 RUS79393.1 - 9.6e-94 314.3 0.0 1.8e-93 313.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ACOX PF01756.19 RUS79393.1 - 0.11 12.0 0.0 0.34 10.5 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA oxidase PALP PF00291.25 RUS79394.1 - 6.9e-75 252.2 5.8 8.8e-75 251.8 5.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 RUS79394.1 - 9e-06 25.4 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 RUS79394.1 - 0.031 14.2 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.6 RUS79394.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 ACT domain PMBR PF09373.10 RUS79395.1 - 2.7e-08 33.6 0.4 45 4.5 0.0 7.6 8 0 0 8 8 8 0 Pseudomurein-binding repeat Rubredoxin_2 PF18073.1 RUS79395.1 - 0.00013 21.6 31.9 9.9 6.0 0.2 8.1 8 0 0 8 8 8 8 Rubredoxin metal binding domain zf-MIZ PF02891.20 RUS79395.1 - 1.3 8.8 40.9 17 5.3 0.3 8.1 3 3 5 8 8 8 0 MIZ/SP-RING zinc finger JTB PF05439.12 RUS79395.1 - 1.3 9.0 6.2 12 6.0 0.4 2.5 1 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) FLYWCH PF04500.16 RUS79395.1 - 6.4 7.0 44.0 8.1 6.6 0.6 7.9 1 1 7 8 8 8 0 FLYWCH zinc finger domain DUF4764 PF15961.5 RUS79397.1 - 4e-06 25.9 10.2 4e-06 25.9 10.2 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF4764) RVT_1 PF00078.27 RUS79398.1 - 9.2e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIX1_SD PF16878.5 RUS79399.1 - 5e-47 159.0 0.6 3.3e-46 156.4 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 RUS79399.1 - 3.1e-12 46.1 3.8 4.2e-12 45.7 1.5 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS79399.1 - 2.3e-10 40.2 1.2 5.3e-10 39.0 1.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 RUS79399.1 - 0.038 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 RUS79399.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Tom22 PF04281.13 RUS79400.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Ras PF00071.22 RUS79402.1 - 2.4e-47 160.6 0.0 2.9e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS79402.1 - 2.1e-19 69.9 0.0 3.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS79402.1 - 0.0014 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS79402.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SH3BP5 PF05276.14 RUS79404.1 - 1.5e-71 240.8 24.5 3.1e-71 239.8 24.5 1.4 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Peptidase_M74 PF03411.13 RUS79404.1 - 0.041 13.4 1.3 0.085 12.4 1.3 1.5 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase UvsY PF11056.8 RUS79404.1 - 0.073 13.4 8.8 0.65 10.4 0.7 2.4 1 1 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY MHB PF16525.5 RUS79404.1 - 0.1 12.9 2.4 0.22 11.8 0.6 2.5 2 0 0 2 2 2 0 Haemophore, haem-binding DPM3 PF08285.11 RUS79404.1 - 0.13 12.5 0.7 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Streptin-Immun PF11083.8 RUS79404.1 - 0.47 10.9 4.6 0.36 11.3 0.8 2.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein ApoO PF09769.9 RUS79404.1 - 0.96 9.4 3.6 1.6 8.7 0.3 2.6 2 0 0 2 2 2 0 Apolipoprotein O Baculo_PEP_C PF04513.12 RUS79404.1 - 1.3 9.1 6.5 9.4 6.3 0.0 3.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 RUS79404.1 - 2.6 8.1 19.3 0.27 11.3 9.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) DUF5446 PF17522.2 RUS79404.1 - 2.9 8.1 10.6 0.6 10.3 0.4 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5446) Phage_GP20 PF06810.11 RUS79404.1 - 3.8 7.3 13.6 1.6 8.5 1.3 2.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 THOC7 PF05615.13 RUS79404.1 - 5.6 7.3 25.9 2.6 8.4 3.6 3.4 3 1 0 3 3 3 0 Tho complex subunit 7 Tup_N PF08581.10 RUS79404.1 - 7 7.0 15.6 3.3 8.1 2.5 3.6 4 1 0 4 4 3 0 Tup N-terminal Prefoldin_2 PF01920.20 RUS79404.1 - 9.4 6.2 15.7 1.6 8.7 0.2 3.3 3 1 0 3 3 2 0 Prefoldin subunit Cation_efflux PF01545.21 RUS79405.1 - 6.9e-46 156.5 11.6 6.9e-46 156.5 11.6 3.4 4 1 0 4 4 4 1 Cation efflux family Dynactin_p22 PF07426.11 RUS79406.1 - 4.8e-42 143.7 7.9 5.6e-42 143.4 7.9 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Phage_TAC_8 PF10666.9 RUS79406.1 - 0.025 14.9 0.4 0.045 14.0 0.4 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 Carn_acyltransf PF00755.20 RUS79407.1 - 2.7e-165 551.4 0.0 3.1e-165 551.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase La PF05383.17 RUS79409.1 - 2.5e-18 65.8 0.6 4.2e-18 65.2 0.6 1.4 1 0 0 1 1 1 1 La domain SUZ-C PF12901.7 RUS79409.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 RUS79409.1 - 0.03 14.1 0.1 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 RUS79409.1 - 8.8 4.5 7.8 13 4.0 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FF PF01846.19 RUS79410.1 - 3.7e-56 187.1 47.5 4e-14 52.5 2.2 6.4 6 0 0 6 6 6 6 FF domain WW PF00397.26 RUS79410.1 - 1.6e-17 63.3 14.8 1.5e-06 28.2 1.0 4.0 3 0 0 3 3 3 3 WW domain RhoGAP-FF1 PF16512.5 RUS79410.1 - 0.0013 19.4 2.6 0.0013 19.4 2.6 4.9 2 2 3 5 5 5 2 p190-A and -B Rho GAPs FF domain Nipped-B_C PF12830.7 RUS79411.1 - 7e-63 212.0 15.6 1.5e-62 211.0 1.4 4.4 4 1 0 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 RUS79411.1 - 1.5e-14 53.9 0.2 6.9e-13 48.6 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 RUS79411.1 - 4.7e-05 23.3 5.3 9.8 6.8 0.0 7.1 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 RUS79411.1 - 0.00026 21.1 12.8 0.14 12.1 0.1 5.2 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 RUS79411.1 - 0.11 11.6 6.8 0.49 9.5 0.0 4.5 5 1 0 6 6 6 0 Nuclear condensing complex subunits, C-term domain Nexin_C PF08628.12 RUS79411.1 - 0.55 10.8 2.2 2.9 8.5 0.0 3.4 2 1 0 2 2 2 0 Sorting nexin C terminal COesterase PF00135.28 RUS79413.1 - 2.7e-77 260.8 0.0 3.2e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS79413.1 - 6.1e-10 39.3 0.7 2.3e-09 37.4 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RUS79413.1 - 0.091 11.6 0.0 0.57 9.0 0.0 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RUS79413.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SID-1_RNA_chan PF13965.6 RUS79414.1 - 4.9e-91 306.0 0.3 7e-91 305.5 0.3 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF2247 PF10004.9 RUS79414.1 - 0.0085 15.9 0.4 0.017 14.9 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2247) BTB PF00651.31 RUS79415.1 - 2.3e-48 163.0 2.7 5.6e-24 84.5 0.1 3.0 3 0 0 3 3 3 2 BTB/POZ domain DUF3342 PF11822.8 RUS79415.1 - 4.6e-07 30.0 1.5 0.0058 16.8 0.1 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3342) BACK PF07707.15 RUS79415.1 - 5.3e-05 23.3 0.0 0.00023 21.2 0.0 2.1 1 0 0 1 1 1 1 BTB And C-terminal Kelch Act-Frag_cataly PF09192.10 RUS79415.1 - 0.013 14.9 0.0 0.93 8.8 0.0 2.7 2 1 0 2 2 2 0 Actin-fragmin kinase, catalytic Spiralin PF05215.13 RUS79415.1 - 0.15 11.4 0.2 0.61 9.4 0.1 1.9 2 0 0 2 2 2 0 Spiralin Ifi-6-16 PF06140.13 RUS79416.1 - 1.1e-13 50.8 31.3 1.4e-13 50.5 31.3 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family HAP2-GCS1 PF10699.9 RUS79418.1 - 0.00059 19.8 0.5 8.2 6.5 0.0 3.4 1 1 3 4 4 4 2 Male gamete fusion factor Erythro-docking PF09277.11 RUS79418.1 - 0.0086 15.9 0.0 0.22 11.4 0.0 2.3 1 1 1 3 3 3 1 Erythronolide synthase, docking HTH_31 PF13560.6 RUS79418.1 - 0.021 15.1 2.5 69 3.9 0.0 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain RHH_7 PF16777.5 RUS79418.1 - 0.023 15.1 1.0 37 4.8 0.0 4.1 1 1 4 5 5 5 0 Transcriptional regulator, RHH-like, CopG Dynein_C PF18199.1 RUS79418.1 - 0.035 13.3 0.3 42 3.2 0.0 3.6 1 1 3 4 4 4 0 Dynein heavy chain C-terminal domain DUF2959 PF11172.8 RUS79418.1 - 0.053 13.7 0.0 15 5.7 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2959) IMPa_helical PF18642.1 RUS79418.1 - 0.07 13.6 0.7 33 4.9 0.1 3.4 1 1 2 3 3 3 0 Immunomodulating metalloprotease helical domain SchA_CurD PF04486.12 RUS79418.1 - 0.073 13.2 0.1 45 4.2 0.1 3.7 1 1 4 5 5 5 0 SchA/CurD like domain TA0956 PF11513.8 RUS79418.1 - 0.076 13.2 0.0 5 7.4 0.0 2.0 1 1 1 2 2 2 0 Thermoplasma acidophilum protein TA0956 RhlB PF12300.8 RUS79418.1 - 0.49 10.5 0.9 25 5.0 0.2 2.8 1 1 3 4 4 4 0 ATP-dependent RNA helicase RhlB UPF0193 PF05250.11 RUS79418.1 - 0.99 9.2 4.8 28 4.4 1.6 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0193) Ig_3 PF13927.6 RUS79419.1 - 6.5e-45 151.6 3.1 4e-14 53.0 0.5 4.4 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS79419.1 - 3.8e-41 139.1 0.7 1.8e-15 56.8 0.1 5.2 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS79419.1 - 7.8e-38 128.7 1.0 2.2e-11 43.9 0.2 4.3 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS79419.1 - 2.4e-26 91.7 3.6 2e-10 40.7 0.5 4.7 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 RUS79419.1 - 7.3e-14 51.9 8.0 0.0078 16.4 0.0 5.7 3 3 1 5 5 5 3 Immunoglobulin V-set domain fn3 PF00041.21 RUS79419.1 - 8.1e-11 42.1 0.1 8.4e-10 38.9 0.0 2.8 3 0 0 3 3 3 1 Fibronectin type III domain C2-set_2 PF08205.12 RUS79419.1 - 8.9e-10 38.5 4.2 9.8e-05 22.4 0.1 3.2 4 0 0 4 4 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS79419.1 - 1.7e-05 24.8 0.1 0.26 11.4 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 RUS79419.1 - 3.9e-05 24.0 3.6 0.018 15.4 0.3 4.4 4 2 0 4 4 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS79419.1 - 6e-05 23.2 3.2 0.13 12.6 0.3 5.0 4 2 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 RUS79419.1 - 0.00046 19.9 2.4 0.21 11.4 0.2 3.0 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 RUS79419.1 - 0.0013 18.8 0.2 0.45 10.6 0.0 3.4 3 1 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 RUS79419.1 - 0.0037 17.4 1.2 5.3 7.3 0.0 3.9 5 0 0 5 5 4 1 Immunoglobulin C2-set domain Ig_6 PF18452.1 RUS79419.1 - 0.004 16.7 0.0 10 5.8 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin domain Herpes_gE PF02480.16 RUS79419.1 - 0.019 13.7 0.1 0.1 11.3 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E C1-set PF07654.15 RUS79419.1 - 0.023 15.1 1.9 0.89 10.0 0.0 3.6 3 2 0 3 3 3 0 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 RUS79419.1 - 0.095 12.9 0.9 31 4.8 0.1 4.0 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 fn3_2 PF16893.5 RUS79419.1 - 0.13 12.4 0.0 1.1 9.5 0.0 2.6 1 1 0 1 1 1 0 Fibronectin type III domain C2-set_2 PF08205.12 RUS79420.1 - 1.3e-10 41.2 0.5 2e-10 40.6 0.5 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 RUS79420.1 - 1.6e-05 25.1 2.3 2.8e-05 24.4 2.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 RUS79420.1 - 5e-05 23.8 0.8 8.8e-05 23.0 0.8 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS79420.1 - 0.012 15.7 0.5 0.018 15.1 0.5 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 RUS79420.1 - 0.041 14.1 0.9 0.079 13.1 0.9 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 RUS79421.1 - 3e-16 59.8 1.2 3.9e-08 33.8 0.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS79421.1 - 3.5e-13 49.5 0.3 2.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS79421.1 - 2e-12 47.3 0.5 3.2e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS79421.1 - 5.3e-12 45.6 0.1 3.3e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.15 RUS79421.1 - 2.1e-10 40.8 0.5 8.4e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 RUS79421.1 - 2.2e-10 40.5 0.4 5.8e-09 35.9 0.1 2.4 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS79421.1 - 1.2e-09 38.3 1.9 1.6e-05 25.0 0.2 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Cadherin-like PF12733.7 RUS79421.1 - 0.077 13.5 0.9 0.15 12.6 0.4 1.7 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain Ig_4 PF16680.5 RUS79421.1 - 0.25 11.6 1.9 10 6.5 0.2 3.4 2 2 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain Kelch_1 PF01344.25 RUS79422.1 - 2.9e-34 116.4 4.0 1.1e-11 44.2 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RUS79422.1 - 3.7e-30 103.2 10.2 6.6e-09 35.7 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RUS79422.1 - 2.6e-29 100.9 4.4 1.5e-08 34.5 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS79422.1 - 2e-25 88.3 0.2 4.8e-09 36.0 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 RUS79422.1 - 2.9e-21 75.2 14.0 1.3e-05 25.3 0.1 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS79422.1 - 3.3e-14 52.2 12.0 9e-06 25.5 0.1 6.0 6 1 0 6 6 6 3 Kelch motif DUF4334 PF14232.6 RUS79422.1 - 0.16 12.0 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) Pou PF00157.17 RUS79424.1 - 1.7e-29 101.6 1.4 2.9e-29 100.8 0.1 2.1 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RUS79424.1 - 8.2e-16 57.6 1.8 8.2e-16 57.6 1.8 1.8 2 0 0 2 2 2 1 Homeodomain HOCHOB PF17943.1 RUS79424.1 - 0.0037 18.0 0.0 0.009 16.7 0.0 1.6 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox HTH_31 PF13560.6 RUS79424.1 - 0.0082 16.5 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Homeobox_KN PF05920.11 RUS79424.1 - 0.043 13.7 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain DERM PF14704.6 RUS79425.1 - 8e-43 146.5 3.1 9.6e-43 146.3 3.1 1.0 1 0 0 1 1 1 1 Dermatopontin Cullin PF00888.22 RUS79426.1 - 2.8e-14 52.7 0.9 3.1e-14 52.5 0.9 1.0 1 0 0 1 1 1 1 Cullin family DPCD PF14913.6 RUS79427.1 - 9.9e-85 282.7 0.6 1.1e-84 282.5 0.6 1.0 1 0 0 1 1 1 1 DPCD protein family NusG_add PF18298.1 RUS79427.1 - 0.018 15.2 0.1 0.041 14.1 0.1 1.5 1 1 0 1 1 1 0 NusG additional domain FAM53 PF15242.6 RUS79428.1 - 1e-13 51.8 23.7 1.3e-12 48.2 23.7 2.1 1 1 0 1 1 1 1 Family of FAM53 Synaptobrevin PF00957.21 RUS79429.1 - 9.8e-16 57.3 0.3 1.7e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RUS79429.1 - 4.8e-13 49.0 0.1 1.6e-12 47.2 0.1 1.9 1 1 0 1 1 1 1 Regulated-SNARE-like domain Fib_alpha PF08702.10 RUS79429.1 - 0.043 14.0 1.4 0.074 13.2 1.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MULE PF10551.9 RUS79430.1 - 1.2e-18 67.3 0.1 4.9e-18 65.3 0.0 1.9 1 1 1 2 2 2 1 MULE transposase domain DUF5575 PF17738.1 RUS79430.1 - 6.1e-07 28.8 0.0 1.5e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5575) Transposase_mut PF00872.18 RUS79430.1 - 0.00069 18.6 0.1 0.0008 18.4 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family AhpC-TSA PF00578.21 RUS79431.1 - 1.1e-37 128.7 0.0 1.6e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS79431.1 - 1.7e-15 57.0 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 7tm_1 PF00001.21 RUS79432.1 - 3.1e-14 52.9 10.3 4.2e-14 52.5 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PPP4R2 PF09184.11 RUS79432.1 - 0.015 14.9 15.9 0.026 14.1 15.9 1.4 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 RUS79432.1 - 0.62 9.9 9.2 0.79 9.5 9.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 RUS79432.1 - 2.1 7.7 27.6 2.7 7.3 27.6 1.1 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 RUS79432.1 - 2.6 7.9 29.6 3.5 7.5 29.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RUS79432.1 - 6.8 4.8 30.5 9.4 4.3 30.5 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS79432.1 - 7.6 5.8 20.4 10 5.3 20.4 1.2 1 0 0 1 1 1 0 BUD22 RRM_1 PF00076.22 RUS79433.1 - 1.2e-17 63.4 0.4 2.3e-17 62.6 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS79433.1 - 0.0011 19.1 0.0 0.004 17.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 RUS79433.1 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif Anoctamin PF04547.12 RUS79435.1 - 6.1e-143 476.9 8.1 7.7e-143 476.6 8.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RUS79435.1 - 0.027 14.2 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Serinc PF03348.15 RUS79436.1 - 1.1e-119 400.2 16.7 1.7e-119 399.6 16.7 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) bZIP_1 PF00170.21 RUS79437.1 - 2.7e-14 53.0 10.3 3.4e-14 52.7 9.4 1.7 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 RUS79437.1 - 2.2e-09 37.2 7.0 3.9e-09 36.4 7.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS79437.1 - 0.00049 20.6 5.8 0.00094 19.6 5.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor RTX PF02382.15 RUS79437.1 - 0.026 14.2 0.2 0.041 13.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein TPR_MLP1_2 PF07926.12 RUS79437.1 - 0.11 12.5 1.8 0.22 11.6 1.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein JMY PF15871.5 RUS79437.1 - 0.26 10.6 4.5 0.4 9.9 4.5 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein COG5 PF10392.9 RUS79437.1 - 0.39 10.9 7.1 4.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 PAS_11 PF14598.6 RUS79438.1 - 1.4e-28 99.3 4.7 1.4e-25 89.6 0.1 2.8 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 RUS79438.1 - 7.2e-26 90.3 0.0 3.5e-18 65.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 RUS79438.1 - 2.7e-20 72.5 0.3 5.1e-12 45.8 0.0 2.6 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 RUS79438.1 - 7.3e-13 48.3 0.7 1.3e-12 47.5 0.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 RUS79438.1 - 3.4e-09 36.9 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 RUS79438.1 - 0.00094 19.4 0.0 0.57 10.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 RUS79438.1 - 0.01 16.5 0.0 0.037 14.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold OAR PF03826.17 RUS79439.1 - 2.3e-07 30.4 0.0 4.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 RUS79439.1 - 0.00018 21.3 0.2 0.00038 20.2 0.2 1.5 1 0 0 1 1 1 1 Homeodomain RR_TM4-6 PF06459.12 RUS79439.1 - 0.0035 17.2 18.7 0.0035 17.2 18.7 2.1 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 RUS79439.1 - 0.0075 16.0 10.3 0.0075 16.0 10.3 2.1 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 RUS79439.1 - 0.64 8.7 22.6 0.89 8.3 22.6 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 RUS79439.1 - 1 8.6 45.9 1.4 8.1 45.9 1.2 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 RUS79439.1 - 1.9 8.4 42.4 0.049 13.6 14.8 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain FYDLN_acid PF09538.10 RUS79439.1 - 2.3 9.0 38.2 0.11 13.1 15.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) AIF_C PF14721.6 RUS79439.1 - 4 7.8 21.8 0.1 13.0 4.9 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_pol_Rpc4 PF05132.14 RUS79439.1 - 5 7.5 24.4 0.26 11.7 6.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Mpp10 PF04006.12 RUS79439.1 - 6.4 5.1 57.4 0.17 10.3 27.5 2.1 2 0 0 2 2 2 0 Mpp10 protein Prothymosin PF03247.14 RUS79439.1 - 6.9 7.2 85.0 1.5 9.3 45.4 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Paf1 PF03985.13 RUS79439.1 - 9 5.2 64.1 0.22 10.5 30.8 2.1 2 0 0 2 2 2 0 Paf1 WD40 PF00400.32 RUS79440.1 - 4.9e-13 49.3 12.3 0.02 15.8 0.0 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79440.1 - 2.5e-09 37.3 0.0 0.012 15.9 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS79440.1 - 0.053 12.5 0.0 2.3 7.1 0.0 2.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UBD PF16455.5 RUS79441.1 - 1e-37 128.5 0.0 1.5e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 RUS79441.1 - 1.9e-14 53.2 0.1 2.7e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RUS79441.1 - 0.011 16.2 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 RUS79441.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Bcl-2 PF00452.19 RUS79442.1 - 3.9e-05 24.3 0.9 6.8e-05 23.5 0.3 1.7 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family MADF_DNA_bdg PF10545.9 RUS79443.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF758 PF05527.11 RUS79444.1 - 1.8e-65 220.3 4.2 2.1e-65 220.1 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF3808 PF10300.9 RUS79444.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) UCH PF00443.29 RUS79445.1 - 4.7e-59 200.0 0.0 6.8e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS79445.1 - 3.1e-25 89.4 1.5 7.7e-24 84.9 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RUS79445.1 - 3.8e-17 62.4 14.1 3.8e-17 62.4 14.1 3.0 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein NUDIX PF00293.28 RUS79446.1 - 1.9e-19 70.0 0.1 2.3e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Kinesin PF00225.23 RUS79447.1 - 8.6e-94 314.2 0.0 1.2e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS79447.1 - 3.3e-16 59.5 0.0 5.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding MFS_1 PF07690.16 RUS79448.1 - 2.7e-23 82.5 34.4 5.5e-11 42.0 9.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Fibrinogen_C PF00147.18 RUS79449.1 - 3.8e-54 183.8 10.0 6.6e-54 183.0 10.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS79449.1 - 0.0056 16.6 11.6 0.049 13.5 1.7 2.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 RUS79449.1 - 0.074 12.8 8.1 0.014 15.2 3.3 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 RUS79449.1 - 0.12 12.4 15.1 0.46 10.5 2.9 3.4 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 RUS79449.1 - 0.33 10.9 4.7 14 5.6 0.1 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Atg14 PF10186.9 RUS79449.1 - 0.57 9.2 5.4 0.34 10.0 3.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 RUS79449.1 - 1.9 9.2 7.7 38 5.0 0.6 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1043 PF06295.12 RUS79449.1 - 3.2 7.8 11.3 0.85 9.6 1.6 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF4164 PF13747.6 RUS79449.1 - 7.7 6.9 10.3 0.69 10.2 1.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Pkinase PF00069.25 RUS79451.1 - 1.4e-60 204.9 0.0 1.6e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79451.1 - 1.1e-29 103.5 0.0 1.4e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS79451.1 - 0.00054 19.4 0.1 0.024 14.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RUS79451.1 - 0.0016 17.5 0.1 0.0054 15.7 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 RUS79451.1 - 0.071 12.1 0.3 0.17 10.9 0.1 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 APH PF01636.23 RUS79451.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4461 PF14688.6 RUS79452.1 - 1.3e-54 186.1 0.7 1.5e-54 185.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) Peptidase_M14 PF00246.24 RUS79453.1 - 3.8e-73 246.8 0.0 6.7e-73 246.0 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 RUS79453.1 - 2.1e-10 40.9 0.7 6.6e-10 39.2 0.0 2.2 3 0 0 3 3 3 1 Carboxypeptidase activation peptide cNMP_binding PF00027.29 RUS79454.1 - 6.4e-09 35.8 0.0 3.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RHD3 PF05879.12 RUS79455.1 - 0.0017 16.6 0.6 0.0021 16.3 0.6 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) dCache_2 PF08269.11 RUS79455.1 - 0.089 12.0 1.0 0.64 9.1 0.1 2.1 2 0 0 2 2 2 0 Cache domain NitrOD2 PF18550.1 RUS79455.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Nitrososphaera output domain 2 Ge1_WD40 PF16529.5 RUS79456.1 - 6e-112 373.8 0.4 8.6e-112 373.3 0.4 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4571 PF15137.6 RUS79456.1 - 0.032 13.9 0.2 0.064 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) TruB_C PF09142.11 RUS79456.1 - 0.11 12.3 0.5 0.53 10.1 0.3 2.2 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal EF-hand_8 PF13833.6 RUS79457.1 - 2.3e-05 24.2 0.2 2.3e-05 24.2 0.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS79457.1 - 4.4e-05 22.7 0.4 9.9e-05 21.6 0.4 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS79457.1 - 0.0034 17.2 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RUS79457.1 - 0.0049 17.3 0.3 0.0078 16.6 0.3 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS79457.1 - 0.032 13.7 0.2 0.083 12.4 0.2 1.6 1 0 0 1 1 1 0 EF hand DUF262 PF03235.14 RUS79457.1 - 0.057 13.6 0.1 0.065 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Dip PF17679.1 RUS79457.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 gp37/Dip protein PEP-utilisers_N PF05524.13 RUS79457.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal kleA_kleC PF17383.2 RUS79457.1 - 0.15 12.4 0.5 0.25 11.7 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A NAM-associated PF14303.6 RUS79457.1 - 0.24 12.1 7.5 0.27 11.9 7.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 RUS79457.1 - 0.7 9.6 6.4 0.83 9.3 6.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Uds1 PF15456.6 RUS79457.1 - 0.71 10.0 3.9 1.8 8.7 3.9 1.7 1 1 0 1 1 1 0 Up-regulated During Septation HH_signal PF01085.18 RUS79458.1 - 3.9e-60 202.2 0.0 3.9e-60 202.2 0.0 2.1 2 0 0 2 2 2 1 Hedgehog amino-terminal signalling domain Hint PF01079.20 RUS79458.1 - 4.7e-35 121.1 0.0 2.3e-24 86.1 0.0 2.5 3 0 0 3 3 3 2 Hint module Peptidase_M15_3 PF08291.11 RUS79458.1 - 0.00036 20.6 2.1 0.00056 20.0 0.3 2.3 2 0 0 2 2 2 1 Peptidase M15 RNA_pol_Rbc25 PF08292.12 RUS79458.1 - 0.46 10.7 3.1 0.95 9.7 3.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Piezo_RRas_bdg PF12166.8 RUS79458.1 - 9.3 5.4 11.1 16 4.6 11.1 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Toxin_7 PF05980.12 RUS79459.1 - 0.24 11.6 69.3 39 4.6 0.2 14.4 1 1 13 14 14 14 0 Toxin 7 MSSP PF03940.13 RUS79459.1 - 0.5 10.0 71.7 1.8e+04 -45.8 71.7 4.9 1 1 0 1 1 1 0 Male specific sperm protein DUF3553 PF12073.8 RUS79460.1 - 0.054 13.2 0.8 17 5.2 0.1 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3553) EF-hand_8 PF13833.6 RUS79460.1 - 0.21 11.4 0.6 1.1e+02 2.7 0.0 5.0 3 1 4 7 7 7 0 EF-hand domain pair MAGI_u5 PF16666.5 RUS79461.1 - 0.00024 21.3 26.9 26 5.0 0.1 9.1 1 1 9 10 10 10 4 Unstructured region on MAGI DUF1087 PF06465.13 RUS79461.1 - 0.001 19.1 9.5 2.2e+02 1.9 0.1 8.8 10 0 0 10 10 10 0 Domain of Unknown Function (DUF1087) DNA_pol3_alpha PF07733.12 RUS79461.1 - 0.053 13.1 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain DUF5434 PF17502.2 RUS79461.1 - 0.25 11.3 2.3 2 8.4 0.6 3.2 1 1 1 2 2 2 0 Family of unknown function (DUF5434) PriCT_2 PF08707.11 RUS79461.1 - 0.52 10.7 7.7 63 4.0 0.1 5.1 2 2 6 8 8 8 0 Primase C terminal 2 (PriCT-2) DUF2439 PF10382.9 RUS79461.1 - 0.7 10.3 7.9 6.5e+02 0.7 0.0 6.7 8 0 0 8 8 8 0 Protein of unknown function (DUF2439) SDA1 PF05285.12 RUS79463.1 - 0.0051 16.3 37.6 0.0055 16.2 37.6 1.1 1 0 0 1 1 1 1 SDA1 RNA_pol_Rpc4 PF05132.14 RUS79463.1 - 0.17 12.3 0.4 0.25 11.8 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 RUS79463.1 - 0.23 10.2 9.6 0.23 10.2 9.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EpsG PF14897.6 RUS79465.1 - 0.00035 20.0 4.7 0.00035 20.0 4.7 1.6 2 0 0 2 2 2 1 EpsG family Glyco_hydro_9 PF00759.19 RUS79467.1 - 3.2e-48 165.2 0.2 4e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 RUS79467.1 - 2.5e-07 30.9 0.0 5.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cellulose binding domain Herpes_capsid PF06112.11 RUS79467.1 - 5.1 7.1 9.7 8.3 6.4 9.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ski2_N PF17911.1 RUS79469.1 - 0.059 13.2 0.6 0.088 12.6 0.6 1.5 1 1 0 1 1 1 0 Ski2 N-terminal region PID PF00640.23 RUS79470.1 - 8.1e-26 90.7 0.2 1.8e-25 89.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS79470.1 - 1.2e-07 31.9 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 RUS79470.1 - 0.0078 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Occludin_ELL PF07303.13 RUS79470.1 - 0.15 12.8 1.9 0.32 11.8 1.9 1.5 1 0 0 1 1 1 0 Occludin homology domain LPD5 PF18799.1 RUS79470.1 - 0.16 12.4 2.1 0.31 11.4 2.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 DUF5316 PF17247.2 RUS79471.1 - 0.12 12.4 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5316) LicD PF04991.13 RUS79472.1 - 2.3e-19 70.5 0.2 7.9e-15 55.6 0.0 2.1 1 1 0 2 2 2 2 LicD family SOG2 PF10428.9 RUS79473.1 - 2.5 7.2 14.8 3.5 6.7 14.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 RUS79473.1 - 8 6.3 5.6 12 5.7 5.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ank_4 PF13637.6 RUS79474.1 - 2.1e-06 28.2 0.4 0.001 19.6 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS79474.1 - 2.6e-06 27.9 2.6 0.0059 17.2 1.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SDA1 PF05285.12 RUS79474.1 - 0.0001 21.9 28.7 0.00013 21.5 28.7 1.1 1 0 0 1 1 1 1 SDA1 Ank_3 PF13606.6 RUS79474.1 - 0.016 15.7 3.5 80 4.3 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat SAPS PF04499.15 RUS79474.1 - 0.023 13.5 3.5 0.029 13.2 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ank_5 PF13857.6 RUS79474.1 - 0.03 14.7 2.1 8.2 6.9 0.1 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DUF4820 PF16091.5 RUS79474.1 - 0.95 8.8 4.4 1.8 7.9 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sulfotransfer_2 PF03567.14 RUS79475.1 - 2.1e-33 116.3 0.1 2.6e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Pkinase_Tyr PF07714.17 RUS79478.1 - 5.8e-52 176.5 0.0 9.6e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 RUS79478.1 - 3.7e-19 68.9 0.3 6.5e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 RUS79478.1 - 4.1e-19 69.0 0.0 6.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 RUS79478.1 - 7.1e-17 61.3 0.6 1.2e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase_Tyr PF07714.17 RUS79479.1 - 2.1e-24 86.2 0.0 2.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.6 RUS79479.1 - 1.9e-19 70.3 0.0 3.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 RUS79479.1 - 1.8e-11 43.9 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 RUS79481.1 - 3.4e-30 104.2 1.0 1.1e-14 54.6 0.2 3.1 3 0 0 3 3 3 3 Fibronectin type III domain fn3_2 PF16893.5 RUS79481.1 - 0.00033 20.8 1.4 1.1 9.4 0.2 2.9 3 1 0 3 3 3 2 Fibronectin type III domain SusE PF14292.6 RUS79481.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 SusE outer membrane protein Ephrin_rec_like PF07699.13 RUS79481.1 - 0.0062 16.3 3.3 0.0062 16.3 3.3 2.7 1 1 1 2 2 2 1 Putative ephrin-receptor like GPI-anchored PF10342.9 RUS79481.1 - 0.013 16.2 0.6 2.2 9.1 0.1 3.3 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 RUS79481.1 - 0.02 15.5 3.9 0.47 11.0 0.8 3.7 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Reeler PF02014.16 RUS79481.1 - 0.052 14.3 0.5 1.8 9.3 0.0 2.9 3 1 0 3 3 3 0 Reeler domain SDA1 PF05285.12 RUS79482.1 - 2 7.7 54.8 2.9 7.2 54.8 1.2 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 RUS79482.1 - 3.2 6.4 9.7 4.6 5.9 9.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ephrin_lbd PF01404.19 RUS79483.1 - 1.3e-43 149.1 0.0 1.5e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain EGF_2 PF07974.13 RUS79483.1 - 0.005 17.2 1.1 0.005 17.2 1.1 2.0 2 0 0 2 2 2 1 EGF-like domain SOSSC PF15925.5 RUS79483.1 - 0.045 15.1 0.0 0.24 12.7 0.0 2.0 2 0 0 2 2 2 0 SOSS complex subunit C hEGF PF12661.7 RUS79483.1 - 0.48 11.1 4.5 4.8 8.0 4.5 2.5 1 1 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 RUS79483.1 - 0.59 10.3 3.5 0.56 10.4 1.3 2.1 2 0 0 2 2 2 0 Laminin EGF domain EGF PF00008.27 RUS79483.1 - 0.65 10.3 5.5 0.56 10.6 2.8 2.3 2 1 0 2 2 2 0 EGF-like domain Sushi PF00084.20 RUS79483.1 - 1.3 9.6 5.8 1.3 9.7 2.0 2.8 2 1 1 3 3 3 0 Sushi repeat (SCR repeat) cEGF PF12662.7 RUS79483.1 - 2.2 8.3 4.3 0.52 10.3 0.6 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like Transposase_1 PF01359.18 RUS79484.1 - 4.8e-06 26.3 0.5 4.8e-06 26.3 0.5 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 RUS79484.1 - 2.7e-05 24.3 0.2 5.5e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS79484.1 - 0.0011 19.5 0.1 0.0011 19.5 0.1 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_48 PF17906.1 RUS79484.1 - 0.0017 18.4 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS79484.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS79484.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 RUS79484.1 - 0.045 13.6 0.6 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain PCI PF01399.27 RUS79484.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 PCI domain DUF4817 PF16087.5 RUS79484.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_26 PF13443.6 RUS79484.1 - 0.07 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS79484.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 EGF_2 PF07974.13 RUS79486.1 - 0.4 11.1 8.2 0.67 10.4 8.2 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.13 RUS79486.1 - 0.52 10.8 4.3 1.1 9.7 3.4 1.8 1 1 1 2 2 2 0 Alliinase EGF-like domain DNA_pol3_chi PF04364.13 RUS79488.1 - 0.047 13.9 0.0 0.065 13.4 0.0 1.3 1 1 0 1 1 1 0 DNA polymerase III chi subunit, HolC zf-C3HC PF07967.13 RUS79489.1 - 2.6e-35 121.4 3.1 4.3e-28 98.0 0.1 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 RUS79489.1 - 1.7e-10 40.9 4.4 1.7e-10 40.9 4.4 3.4 4 1 0 4 4 4 1 Rsm1-like PHBC_N PF12551.8 RUS79489.1 - 0.034 13.9 0.2 0.07 12.9 0.2 1.5 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal Aldo_ket_red PF00248.21 RUS79489.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Aldo/keto reductase family BIR PF00653.21 RUS79489.1 - 1.4 9.6 0.1 1.4 9.6 0.1 3.3 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain UQ_con PF00179.26 RUS79490.1 - 1e-36 125.7 0.0 1.2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CBM_14 PF01607.24 RUS79491.1 - 1.8e-10 40.8 28.4 3.5e-07 30.3 2.9 3.8 4 0 0 4 4 4 3 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 RUS79491.1 - 0.022 14.5 2.9 0.12 12.0 0.3 2.2 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Dpy-30 PF05186.13 RUS79491.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif zf-MYND PF01753.18 RUS79491.1 - 1.5 9.0 9.9 0.42 10.8 5.5 2.5 2 0 0 2 2 2 0 MYND finger cEGF PF12662.7 RUS79491.1 - 1.8 8.6 5.4 0.51 10.3 1.3 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like Synapsin_C PF02750.14 RUS79493.1 - 3.1e-48 164.0 0.1 3.5e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Synapsin, ATP binding domain Cir_N PF10197.9 RUS79496.1 - 2.8e-08 33.8 11.5 2.8e-08 33.8 11.5 5.7 5 2 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Anoctamin PF04547.12 RUS79496.1 - 0.22 10.3 1.6 0.39 9.5 1.6 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel MRP-S23 PF10484.9 RUS79497.1 - 1.6e-34 118.9 0.1 3e-34 118.0 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 RUS79497.1 - 0.00018 21.2 5.2 0.0038 16.8 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S25 PSD4 PF07631.11 RUS79497.1 - 0.048 14.2 0.1 0.071 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) FKBP_C PF00254.28 RUS79498.1 - 1.1e-21 76.9 0.0 2.1e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 RUS79498.1 - 6.1e-05 22.8 0.3 0.42 10.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS79498.1 - 0.00045 19.9 1.2 0.047 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS79498.1 - 0.015 15.0 0.6 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 RUS79498.1 - 0.02 15.1 0.5 0.98 9.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS79498.1 - 0.039 14.2 4.7 2.2 8.5 0.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PaREP1 PF05942.11 RUS79498.1 - 0.21 11.5 1.0 12 5.9 0.0 2.6 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family Thioredoxin_4 PF13462.6 RUS79499.1 - 0.00047 20.4 0.0 0.00061 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phage_integrase PF00589.22 RUS79500.1 - 0.00016 21.5 0.2 0.0011 18.8 0.3 2.4 2 1 0 2 2 2 1 Phage integrase family 7tm_1 PF00001.21 RUS79503.1 - 3.6e-10 39.6 11.6 5.9e-10 38.9 11.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS79503.1 - 5.9e-08 32.4 11.9 1e-06 28.3 11.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS79503.1 - 0.00081 18.8 13.2 0.0028 17.1 13.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.21 RUS79503.1 - 0.33 10.6 13.4 0.064 12.9 7.7 2.3 1 1 1 2 2 2 0 Srg family chemoreceptor Patched PF02460.18 RUS79504.1 - 1.8e-72 244.7 21.0 1.9e-47 161.9 0.3 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RUS79504.1 - 2.6e-41 141.0 2.8 2.6e-41 141.0 2.8 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DoxX_3 PF13781.6 RUS79504.1 - 1 10.0 5.9 4.6 7.9 0.5 2.8 2 0 0 2 2 2 0 DoxX-like family NICE-1 PF15845.5 RUS79504.1 - 2.6 8.9 6.8 0.22 12.3 1.8 1.8 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family zf-HC5HC2H_2 PF13832.6 RUS79505.1 - 1.1e-35 122.1 8.5 1.1e-35 122.1 8.5 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 RUS79505.1 - 1.5e-26 93.7 6.5 1.5e-26 93.7 6.5 3.9 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 RUS79505.1 - 1.2e-23 83.1 4.1 1.2e-23 83.1 4.1 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain Bromodomain PF00439.25 RUS79505.1 - 1.5e-21 76.2 1.0 3.4e-21 75.1 1.0 1.6 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 RUS79505.1 - 3.4e-18 65.8 0.2 1.3e-17 64.0 0.2 2.1 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 RUS79505.1 - 1e-14 53.8 2.7 1e-14 53.8 2.7 2.7 2 1 1 3 3 3 1 PHD-finger PHD PF00628.29 RUS79505.1 - 1.5e-08 34.4 23.9 1.8e-07 30.9 9.2 2.9 2 0 0 2 2 2 2 PHD-finger Glyco_transf_11 PF01531.16 RUS79508.1 - 0.12 11.6 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 11 DUF2048 PF09752.9 RUS79509.1 - 4.8e-148 493.0 0.0 6.1e-148 492.6 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Peptidase_S9 PF00326.21 RUS79509.1 - 0.042 13.3 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NHL PF01436.21 RUS79511.1 - 2.2e-20 71.6 11.0 0.00025 20.9 0.1 4.7 4 0 0 4 4 4 4 NHL repeat zf-C3HC4_3 PF13920.6 RUS79511.1 - 0.001 18.9 11.4 0.001 18.9 11.4 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 RUS79511.1 - 0.0014 18.7 22.0 0.0019 18.3 8.1 3.8 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 RUS79511.1 - 0.0042 16.9 13.1 0.0042 16.9 13.1 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 RUS79511.1 - 0.005 16.0 0.1 8.4 5.4 0.0 4.3 4 0 0 4 4 4 1 6-bladed beta-propeller SGL PF08450.12 RUS79511.1 - 0.022 14.3 0.0 2.3 7.8 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region TPR_12 PF13424.6 RUS79512.1 - 6e-20 71.3 7.5 2.8e-09 37.1 0.0 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS79512.1 - 6.1e-14 50.9 9.3 0.011 15.8 0.2 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 RUS79512.1 - 1.3e-13 50.1 10.0 8.6e-05 22.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS79512.1 - 2.2e-10 39.8 4.4 0.0027 17.6 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS79512.1 - 2.4e-09 36.7 14.3 0.00095 19.2 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS79512.1 - 1.1e-07 31.5 3.5 0.00029 20.6 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 RUS79512.1 - 5.1e-07 29.6 3.2 0.00011 22.0 0.2 2.4 2 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_6 PF13174.6 RUS79512.1 - 2e-05 24.9 1.4 1.9 9.3 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS79512.1 - 3.9e-05 24.1 0.2 35 5.6 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS79512.1 - 0.00017 21.6 0.4 0.05 13.7 0.1 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 RUS79512.1 - 0.00055 19.4 0.0 0.0022 17.4 0.0 1.9 1 1 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 RUS79512.1 - 0.0013 19.1 1.1 5.8 7.5 0.6 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS79512.1 - 0.11 12.9 2.1 4 8.0 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 RUS79513.1 - 1.3e-134 448.8 1.8 1.3e-134 448.8 1.8 2.1 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 RUS79513.1 - 3.7e-08 33.5 0.1 8.9e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RUS79513.1 - 0.00011 22.6 0.1 0.00031 21.2 0.1 1.8 1 0 0 1 1 1 1 PH domain MULE PF10551.9 RUS79514.1 - 1.2e-10 41.6 0.0 3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 RUS79514.1 - 0.0085 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family PMAIP1 PF15150.6 RUS79514.1 - 0.28 11.1 2.6 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced RepB PF07506.11 RUS79515.1 - 0.011 15.8 0.2 3.4 7.7 0.1 3.0 2 2 1 3 3 3 0 RepB plasmid partitioning protein Ribosomal_L31e PF01198.19 RUS79515.1 - 0.12 12.7 1.9 17 5.7 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L31e JMY PF15871.5 RUS79516.1 - 0.0085 15.4 0.1 0.0099 15.2 0.1 1.2 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein JmjC PF02373.22 RUS79517.1 - 1.2e-21 77.2 0.6 4.1e-21 75.5 0.6 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 RUS79517.1 - 7.1e-13 48.3 0.1 1.5e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 RUS79517.1 - 7.5e-11 42.3 2.9 1.7e-10 41.1 2.9 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger ARID PF01388.21 RUS79517.1 - 2.8e-10 40.7 0.0 8.4e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2_4 PF13894.6 RUS79518.1 - 6.4e-16 57.7 102.5 0.0019 18.9 0.7 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS79518.1 - 1.9e-13 50.0 101.7 0.00026 21.3 3.0 12.6 12 1 0 12 12 12 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS79518.1 - 3.7e-13 49.2 28.9 4.6e-06 26.8 1.2 12.3 14 1 1 15 15 15 5 Zinc-finger double domain DUF4573 PF15140.6 RUS79518.1 - 6.2e-05 22.9 9.8 0.00018 21.4 9.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) zf-C2H2_jaz PF12171.8 RUS79518.1 - 0.018 15.3 60.4 0.94 9.8 2.0 9.7 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS79518.1 - 0.04 14.3 0.4 0.04 14.3 0.4 9.6 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RUS79518.1 - 0.18 12.5 0.3 0.18 12.5 0.3 7.4 5 4 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats YacG PF03884.14 RUS79518.1 - 3.1 7.6 9.8 2.5 7.9 0.1 3.3 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-RING_7 PF02591.15 RUS79518.1 - 3.6 7.8 18.0 3.2 8.0 0.1 5.5 6 0 0 6 6 6 0 C4-type zinc ribbon domain BRCT_assoc PF12820.7 RUS79518.1 - 9.3 6.0 9.9 0.093 12.5 0.6 2.4 3 0 0 3 3 3 0 Serine-rich domain associated with BRCT Glyco_hydro_16 PF00722.21 RUS79519.1 - 1.6e-17 63.5 0.7 1.6e-17 63.5 0.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Branch_AA_trans PF05525.13 RUS79519.1 - 0.21 10.4 0.7 7.4 5.3 0.0 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein zf-H2C2_2 PF13465.6 RUS79520.1 - 7.1e-24 83.1 146.4 9.8e-05 22.6 4.3 15.9 16 0 0 16 16 16 11 Zinc-finger double domain zf-C2H2 PF00096.26 RUS79520.1 - 2.2e-18 65.6 139.6 0.0009 19.6 2.8 15.7 15 1 0 15 15 15 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS79520.1 - 6.6e-14 51.4 129.7 0.002 18.8 5.3 15.6 15 0 0 15 15 15 11 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS79520.1 - 6.2e-10 38.7 20.1 1.9e-06 27.5 2.0 12.9 14 0 0 14 14 14 7 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS79520.1 - 1.8 8.9 85.4 0.1 12.9 2.4 10.4 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding UNC-93 PF05978.16 RUS79522.1 - 4e-06 26.6 4.2 4e-06 26.6 4.2 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 RUS79522.1 - 1.2e-05 24.4 38.0 4.1e-05 22.7 7.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS79522.1 - 0.0014 17.6 1.5 0.0014 17.6 1.5 2.7 2 1 1 3 3 3 2 MFS_1 like family HA2 PF04408.23 RUS79523.1 - 3.1e-19 69.3 0.0 3.1e-19 69.3 0.0 4.5 5 1 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS79523.1 - 3.4e-16 59.4 0.0 8.3e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS79523.1 - 3.3e-12 46.7 0.0 7.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS79523.1 - 1.7e-06 27.9 0.1 3.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS79523.1 - 3e-06 27.6 0.1 7.3e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS79523.1 - 0.00034 21.0 0.2 0.0011 19.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 RUS79523.1 - 0.0021 17.2 0.0 0.0046 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 RUS79523.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RUS79523.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 RUS79523.1 - 0.028 14.4 0.1 0.061 13.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain IstB_IS21 PF01695.17 RUS79523.1 - 0.058 13.1 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 RUS79523.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 RUS79523.1 - 0.13 12.3 0.5 1.3 9.0 0.2 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RUS79523.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 RUS79523.1 - 0.29 11.1 5.0 5.2 7.0 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 RUS79523.1 - 0.32 11.5 1.9 0.81 10.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter fn3 PF00041.21 RUS79524.1 - 0.031 14.6 0.9 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain LRR_8 PF13855.6 RUS79525.1 - 3.5e-28 97.1 44.0 3.2e-08 33.2 8.8 4.4 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS79525.1 - 1e-23 83.0 40.2 2.2e-05 24.7 4.9 6.3 2 2 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS79525.1 - 0.00028 20.4 8.0 0.012 15.1 4.0 3.0 1 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 RUS79525.1 - 0.002 18.4 23.9 2.2 9.2 0.4 8.0 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 RUS79525.1 - 0.32 11.2 15.5 6 7.2 0.6 6.4 7 0 0 7 7 7 0 Leucine Rich repeat ABC_membrane PF00664.23 RUS79526.1 - 3e-39 135.3 8.1 4e-39 134.9 8.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS79526.1 - 1.1e-33 116.6 0.0 4.4e-33 114.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RUS79526.1 - 0.0022 17.5 0.1 0.34 10.3 0.1 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 RUS79526.1 - 0.007 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 RUS79526.1 - 0.0079 16.6 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS79526.1 - 0.011 15.5 1.9 0.012 15.3 0.2 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 RUS79526.1 - 0.016 15.0 0.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RUS79526.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RUS79526.1 - 0.033 13.5 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 RUS79526.1 - 0.074 12.2 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 RUS79526.1 - 0.077 13.1 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 RUS79526.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RUS79526.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 RUS79526.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RUS79526.1 - 0.12 12.6 0.8 0.41 10.9 0.3 2.0 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RUS79526.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS79526.1 - 0.16 12.3 0.0 0.56 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Pepsin-I3 PF06394.13 RUS79526.1 - 0.98 9.7 6.1 8.1 6.7 0.1 3.8 4 0 0 4 4 4 0 Pepsin inhibitor-3-like repeated domain AAA_23 PF13476.6 RUS79526.1 - 1.3 9.4 4.0 0.41 11.1 0.6 1.8 2 0 0 2 2 1 0 AAA domain Reprolysin PF01421.19 RUS79527.1 - 6.6e-41 140.4 0.0 6.6e-41 140.4 0.0 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 RUS79527.1 - 7e-29 100.8 3.2 2e-28 99.4 3.2 1.8 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.12 RUS79527.1 - 8.7e-27 93.8 7.5 8.7e-27 93.8 7.5 3.2 4 0 0 4 4 4 1 ADAM cysteine-rich Disintegrin PF00200.23 RUS79527.1 - 4.7e-20 72.2 27.4 4.7e-20 72.2 27.4 3.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_5 PF13688.6 RUS79527.1 - 2.4e-10 40.9 0.0 2.4e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS79527.1 - 2.6e-05 24.2 0.2 6.3e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS79527.1 - 3.2e-05 24.5 0.0 8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 RUS79527.1 - 5.1e-05 23.6 6.7 5.1e-05 23.6 6.7 5.9 4 1 1 5 5 5 1 EGF-like domain Reprolysin_4 PF13583.6 RUS79527.1 - 7.8e-05 22.4 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Cwf_Cwc_15 PF04889.12 RUS79527.1 - 2.8 7.6 6.5 5.5 6.6 6.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein p450 PF00067.22 RUS79528.1 - 4.4e-106 355.4 0.0 5e-106 355.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.21 RUS79529.1 - 2.1e-05 24.0 5.3 2.9e-05 23.5 5.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS79529.1 - 0.012 14.9 1.1 0.012 14.9 1.1 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS79529.1 - 0.13 11.9 10.7 0.19 11.3 10.7 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx His_Phos_1 PF00300.22 RUS79530.1 - 8.3e-16 58.2 0.0 2.8e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.6 RUS79530.1 - 4.6e-10 39.2 0.0 1.6e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain UBA PF00627.31 RUS79531.1 - 2.9e-06 27.1 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Jnk-SapK_ap_N PF09744.9 RUS79532.1 - 6.1e-30 104.5 22.2 6.1e-30 104.5 22.2 3.4 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 RILP PF11461.8 RUS79532.1 - 1.2e-14 54.3 0.2 1.2e-14 54.3 0.2 4.1 5 1 0 5 5 5 1 Rab interacting lysosomal protein DUF2935 PF11155.8 RUS79532.1 - 0.12 12.7 13.2 4.4 7.6 4.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) GCP_C_terminal PF04130.13 RUS79532.1 - 8.6 5.7 11.2 0.087 12.3 1.9 2.1 1 1 0 2 2 2 0 Gamma tubulin complex component C-terminal AAA_34 PF13872.6 RUS79533.1 - 8.1e-138 458.4 0.0 1.2e-137 457.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 RUS79533.1 - 9.7e-120 399.3 0.1 1.7e-119 398.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 RUS79533.1 - 2.5e-07 30.8 0.0 2.5e-07 30.8 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SR-25 PF10500.9 RUS79533.1 - 0.0028 17.3 24.4 0.0028 17.3 24.4 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FAM177 PF14774.6 RUS79533.1 - 0.051 14.0 1.9 0.075 13.4 0.2 2.2 2 0 0 2 2 2 0 FAM177 family Helicase_C PF00271.31 RUS79533.1 - 0.09 13.1 0.0 0.4 11.0 0.0 2.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PHD_4 PF16866.5 RUS79534.1 - 3.5e-20 71.8 12.0 3.5e-20 71.8 12.0 2.5 2 0 0 2 2 2 1 PHD-finger zf-CXXC PF02008.20 RUS79534.1 - 5.1e-14 52.0 22.5 5.1e-14 52.0 22.5 2.5 2 0 0 2 2 2 1 CXXC zinc finger domain JHD PF17811.1 RUS79534.1 - 6.5e-06 26.6 0.1 2.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Jumonji helical domain LRR_6 PF13516.6 RUS79534.1 - 8.1e-06 25.5 4.9 0.35 11.0 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.7 RUS79534.1 - 8.8e-06 25.5 6.0 2.3e-05 24.2 6.0 1.8 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 RUS79534.1 - 2.8e-05 24.5 0.7 0.0027 18.1 0.7 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RUS79534.1 - 3.4e-05 23.7 0.0 0.0006 19.6 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain LRR_4 PF12799.7 RUS79534.1 - 5.4e-05 23.5 2.0 1.2 9.7 0.1 3.9 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS79534.1 - 0.0005 19.8 4.0 0.21 11.3 0.2 3.6 3 0 0 3 3 3 2 Leucine rich repeat F-box PF00646.33 RUS79534.1 - 0.001 18.9 1.0 0.001 18.9 1.0 2.3 2 0 0 2 2 2 1 F-box domain CRAL_TRIO PF00650.20 RUS79536.1 - 9.6e-29 100.2 0.5 1.7e-28 99.3 0.1 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain GOLD_2 PF13897.6 RUS79536.1 - 1.8e-13 51.1 0.7 2.3e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 RUS79536.1 - 4.8e-06 26.8 0.1 9.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EMP24_GP25L PF01105.24 RUS79536.1 - 0.0003 20.8 0.2 0.00051 20.0 0.2 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRAL_TRIO_N PF03765.15 RUS79536.1 - 0.016 15.4 0.3 0.054 13.7 0.3 2.0 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain PKD_channel PF08016.12 RUS79538.1 - 2.4e-31 108.9 5.0 1.1e-25 90.3 0.1 3.3 1 1 2 3 3 3 3 Polycystin cation channel PLAT PF01477.23 RUS79538.1 - 0.00029 21.4 0.0 0.019 15.5 0.0 2.7 2 0 0 2 2 2 1 PLAT/LH2 domain Tmemb_185A PF10269.9 RUS79538.1 - 0.066 12.9 2.6 0.079 12.6 0.9 2.0 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein GETHR PF05671.11 RUS79538.1 - 1.6 8.2 42.0 6.7e+02 -0.2 7.7 7.4 1 1 1 2 2 2 0 GETHR pentapeptide repeat (5 copies) ABC2_membrane_2 PF12679.7 RUS79538.1 - 1.8 7.8 6.2 6.3 6.0 6.2 1.9 1 0 0 1 1 1 0 ABC-2 family transporter protein TFIIA PF03153.13 RUS79539.1 - 1.9e-07 31.5 17.7 1.9e-07 31.5 17.7 3.2 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF3224 PF11528.8 RUS79539.1 - 0.0057 16.5 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) cwf18 PF08315.12 RUS79539.1 - 6.2 7.5 7.7 6.6 7.4 0.7 3.0 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor cNMP_binding PF00027.29 RUS79540.1 - 9.5e-25 86.5 0.1 1.1e-15 57.4 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 RUS79540.1 - 2.4e-21 76.1 9.0 3.9e-21 75.4 9.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS79540.1 - 0.003 17.5 1.3 0.0094 15.9 1.3 1.8 1 1 0 1 1 1 1 Ion channel Sigma70_ner PF04546.13 RUS79540.1 - 0.65 9.8 5.2 1.2 9.0 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 RUS79540.1 - 1.2 7.4 6.9 1.8 6.8 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 RUS79540.1 - 2.3 8.2 6.6 4.5 7.3 6.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Voldacs PF03517.13 RUS79540.1 - 4.6 7.3 9.2 8.2 6.5 9.2 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF2457 PF10446.9 RUS79540.1 - 5.3 6.1 27.1 0.044 12.9 17.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) ANAPC15 PF15243.6 RUS79540.1 - 6.7 7.2 14.0 13 6.3 14.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF1676 PF07898.13 RUS79542.1 - 0.00042 20.4 0.1 0.00058 19.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) Orf78 PF06024.12 RUS79542.1 - 0.0015 18.8 0.2 0.0021 18.3 0.2 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DNA_pol_phi PF04931.13 RUS79542.1 - 0.32 9.0 23.3 0.42 8.7 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 RUS79542.1 - 0.56 10.0 3.4 0.67 9.8 3.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rhabdo_ncap PF00945.18 RUS79542.1 - 0.76 8.6 6.3 0.99 8.2 6.3 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein GCIP PF13324.6 RUS79542.1 - 1.1 8.7 13.7 1.5 8.3 13.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 RUS79542.1 - 1.5 7.3 15.5 1.9 6.9 15.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 RUS79542.1 - 3.8 7.5 13.1 5.8 6.9 13.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Cnn_1N PF07989.11 RUS79543.1 - 0.0064 16.6 8.9 0.0064 16.6 8.9 15.2 8 4 7 15 15 15 1 Centrosomin N-terminal motif 1 PUB PF09409.10 RUS79543.1 - 0.42 10.6 6.3 1.4 8.9 0.1 3.7 4 0 0 4 4 4 0 PUB domain HIT PF01230.23 RUS79543.1 - 3.2 8.5 8.9 1.6 9.5 0.1 4.3 4 0 0 4 4 4 0 HIT domain CALCOCO1 PF07888.11 RUS79544.1 - 0.001 18.0 31.9 0.001 18.0 31.9 8.4 3 1 6 9 9 9 2 Calcium binding and coiled-coil domain (CALCOCO1) like Spectrin PF00435.21 RUS79544.1 - 0.0052 17.3 19.2 0.0052 17.3 19.2 14.7 5 4 11 16 16 16 1 Spectrin repeat Spem1 PF15670.5 RUS79546.1 - 0.074 12.6 2.1 0.1 12.2 2.1 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1356 PF07092.12 RUS79547.1 - 4e-45 153.9 0.0 5.5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 RUS79547.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein SlyX PF04102.12 RUS79548.1 - 0.00014 22.5 1.6 0.00014 22.5 1.6 4.7 3 1 1 4 4 4 1 SlyX Spc24 PF08286.11 RUS79548.1 - 0.046 14.0 0.4 0.046 14.0 0.4 4.0 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 RUS79548.1 - 0.057 12.8 14.5 0.12 11.7 12.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 RUS79548.1 - 1 9.8 9.8 7.5 6.9 0.1 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) TolA_bind_tri PF16331.5 RUS79548.1 - 5.1 7.3 27.2 1 9.5 2.4 4.5 4 1 0 4 4 4 0 TolA binding protein trimerisation IRS PF02174.17 RUS79549.1 - 8.4e-14 51.3 0.1 1.9e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) AAA_23 PF13476.6 RUS79549.1 - 0.03 14.8 19.1 0.05 14.1 19.1 1.3 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.14 RUS79549.1 - 0.031 13.5 19.8 0.048 12.9 19.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Borrelia_P83 PF05262.11 RUS79549.1 - 0.15 10.5 26.1 0.21 10.0 26.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IMD PF08397.11 RUS79549.1 - 0.39 10.0 16.6 0.65 9.3 16.6 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Exonuc_VII_L PF02601.15 RUS79549.1 - 0.77 9.3 10.2 1 8.9 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 RUS79549.1 - 1.8 8.3 22.0 3.3 7.4 22.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 RUS79549.1 - 2.2 5.3 10.6 2.3 5.2 10.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec62 PF03839.16 RUS79549.1 - 6.8 6.1 14.8 13 5.2 14.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Vps5 PF09325.10 RUS79550.1 - 2.3e-76 256.5 20.9 3.3e-76 255.9 20.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 RUS79550.1 - 1.7e-22 79.5 0.1 6.9e-22 77.6 0.0 2.1 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.9 RUS79550.1 - 1.6e-05 24.5 7.0 0.00092 18.7 6.3 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Spc7 PF08317.11 RUS79550.1 - 0.54 9.1 19.2 1.6 7.5 10.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.10 RUS79550.1 - 0.55 10.6 8.3 5.2 7.4 0.6 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) CLAMP PF14769.6 RUS79551.1 - 3.7e-22 78.6 0.1 4.6e-21 75.1 0.2 2.1 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 DJ-1_PfpI PF01965.24 RUS79552.1 - 1.3e-07 31.6 0.1 4.5e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 RUS79552.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 C-terminal domain found in long catalases Nop14 PF04147.12 RUS79553.1 - 2.1e-198 661.6 38.2 2.4e-198 661.4 38.2 1.0 1 0 0 1 1 1 1 Nop14-like family Dsh_C PF12316.8 RUS79553.1 - 5.1 7.4 6.4 17 5.7 6.4 1.9 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Tmpp129 PF10272.9 RUS79554.1 - 9.3e-136 452.8 0.0 1.1e-135 452.6 0.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor THAP PF05485.12 RUS79555.1 - 1.4e-13 51.6 1.3 3.9e-13 50.1 1.3 1.9 1 0 0 1 1 1 1 THAP domain DivIC PF04977.15 RUS79555.1 - 0.07 12.9 1.8 0.13 12.1 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator ShK PF01549.24 RUS79556.1 - 7.3e-12 45.6 44.0 2.8e-06 27.8 10.5 3.2 3 0 0 3 3 3 3 ShK domain-like DUF3439 PF11921.8 RUS79556.1 - 0.043 13.8 12.0 0.071 13.1 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DICT PF10069.9 RUS79556.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Trypsin_2 PF13365.6 RUS79557.1 - 0.0058 17.5 0.1 0.01 16.7 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Alpha-mann_mid PF09261.11 RUS79559.1 - 2.3e-10 40.5 0.0 3.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Alpha mannosidase middle domain Aminotran_5 PF00266.19 RUS79560.1 - 2e-14 53.4 0.5 4.7e-13 48.8 0.5 2.6 1 1 0 1 1 1 1 Aminotransferase class-V Pec_lyase_N PF04431.13 RUS79560.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Pectate lyase, N terminus fn3 PF00041.21 RUS79561.1 - 9.4e-17 61.1 3.1 6e-07 29.7 0.0 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS79561.1 - 0.0002 21.9 4.0 0.44 11.1 0.7 3.4 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 RUS79561.1 - 0.05 13.8 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Fibronectin type III domain SOUL PF04832.12 RUS79562.1 - 1.9e-47 161.6 0.1 2.2e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein IF4E PF01652.18 RUS79563.1 - 3.3e-46 157.0 0.9 3.8e-46 156.8 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CtsR_C PF17727.1 RUS79564.1 - 5.5e-05 23.2 0.0 4.3 7.5 0.0 3.2 3 0 0 3 3 3 3 CtsR C-terminal dimerization domain RasGEF PF00617.19 RUS79564.1 - 0.0025 18.0 0.1 15 5.7 0.0 3.0 3 0 0 3 3 3 3 RasGEF domain DUF1844 PF08899.11 RUS79564.1 - 0.016 15.5 0.1 65 3.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) DUF5529 PF17669.1 RUS79565.1 - 0.031 14.3 0.3 0.066 13.3 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5529) Nop14 PF04147.12 RUS79566.1 - 0.00016 20.1 28.5 0.00018 19.9 28.5 1.2 1 0 0 1 1 1 1 Nop14-like family SID-1_RNA_chan PF13965.6 RUS79566.1 - 0.027 12.9 5.1 0.036 12.5 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 RUS79566.1 - 0.25 10.8 16.1 0.34 10.3 16.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 RUS79566.1 - 0.3 9.9 6.2 0.55 9.1 6.2 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2828 PF11443.8 RUS79566.1 - 1.3 7.0 9.7 1.6 6.7 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 RUS79566.1 - 2.8 7.3 41.4 4.2 6.7 41.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ureide_permease PF07168.11 RUS79566.1 - 4.9 5.8 5.3 7.8 5.1 5.3 1.2 1 0 0 1 1 1 0 Ureide permease V-set PF07686.17 RUS79567.1 - 1.6e-09 37.9 0.0 0.0052 16.9 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin V-set domain I-set PF07679.16 RUS79567.1 - 3e-08 33.6 0.0 0.01 15.9 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS79567.1 - 8.1e-08 32.8 0.0 0.00022 21.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS79567.1 - 2.7e-06 27.4 0.0 0.66 10.2 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS79567.1 - 9e-05 22.7 0.0 0.029 14.7 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS79567.1 - 0.003 17.1 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 RUS79567.1 - 0.0098 15.9 0.0 0.057 13.5 0.0 2.0 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS79567.1 - 0.11 12.8 0.0 8 6.8 0.0 2.2 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain G6B PF15096.6 RUS79567.1 - 0.12 12.1 0.1 0.62 9.8 0.0 1.8 1 1 1 2 2 2 0 G6B family MIR PF02815.19 RUS79568.1 - 0.037 13.9 1.1 0.067 13.0 1.1 1.4 1 0 0 1 1 1 0 MIR domain GPP34 PF05719.11 RUS79569.1 - 2e-60 204.3 0.6 2.7e-60 203.9 0.6 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PIN_2 PF10130.9 RUS79570.1 - 0.061 13.6 0.2 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 PIN domain Polysacc_deac_1 PF01522.21 RUS79571.1 - 4.1e-05 23.5 0.0 0.00015 21.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase PDZ PF00595.24 RUS79572.1 - 9.5e-11 41.9 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS79572.1 - 1.6e-05 24.6 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS79572.1 - 0.00051 20.3 0.1 0.0015 18.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS79573.1 - 3.9e-22 78.4 0.3 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS79573.1 - 9.4e-14 51.0 0.0 8.8e-06 25.5 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS79573.1 - 0.00025 21.3 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Maf_N PF08383.11 RUS79573.1 - 0.0054 16.5 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Maf N-terminal region FYRC PF05965.14 RUS79573.1 - 0.22 11.7 0.1 19 5.5 0.0 2.2 2 0 0 2 2 2 0 F/Y rich C-terminus PDZ PF00595.24 RUS79574.1 - 3.5e-07 30.5 0.1 0.0095 16.3 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Macoilin PF09726.9 RUS79574.1 - 0.23 9.9 3.0 0.3 9.6 3.0 1.1 1 0 0 1 1 1 0 Macoilin family TPR_1 PF00515.28 RUS79575.1 - 1.7e-14 52.9 0.3 0.0002 21.0 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS79575.1 - 9.2e-14 50.4 0.0 0.00095 19.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS79575.1 - 1.4e-11 43.9 0.1 1.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat CS PF04969.16 RUS79575.1 - 3.1e-06 28.1 0.0 6.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.6 RUS79575.1 - 3.3e-06 27.3 0.3 0.72 10.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS79575.1 - 2.5e-05 24.8 0.0 0.0018 18.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS79575.1 - 9.2e-05 22.4 2.5 0.029 14.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS79575.1 - 0.0034 18.1 0.1 3.1 8.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS79575.1 - 0.0055 16.8 3.1 1.3 9.2 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS79575.1 - 0.0063 16.8 0.2 2.1 8.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS79575.1 - 0.013 15.4 0.1 0.35 11.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4800 PF16057.5 RUS79575.1 - 0.023 13.9 12.7 0.023 14.0 11.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) TPR_19 PF14559.6 RUS79575.1 - 0.035 14.6 0.0 1.9 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPE PF00823.19 RUS79575.1 - 0.088 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 PPE family LSM PF01423.22 RUS79576.1 - 1.3e-18 66.4 0.2 1.5e-18 66.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RUS79576.1 - 0.0002 21.4 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 RUS79576.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein WBP-1 PF11669.8 RUS79577.1 - 0.72 10.5 11.3 0.72 10.5 10.6 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 7tm_1 PF00001.21 RUS79578.1 - 1.1e-16 61.0 23.8 1.3e-16 60.7 23.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS79578.1 - 0.00026 20.4 18.1 0.0016 17.8 2.4 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS79578.1 - 0.072 12.4 27.0 0.14 11.5 27.0 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DSPc PF00782.20 RUS79580.1 - 7.1e-37 126.2 0.1 2.4e-36 124.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RUS79580.1 - 1.6e-06 28.6 0.0 4.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RUS79580.1 - 0.0022 17.6 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase OTU PF02338.19 RUS79581.1 - 5.9e-31 107.6 0.0 1.2e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease AnkUBD PF18418.1 RUS79581.1 - 3.5e-26 91.2 0.0 7.1e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain zf-RanBP PF00641.18 RUS79581.1 - 1.1e-11 43.8 29.2 7.7e-06 25.1 3.5 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 RUS79581.1 - 0.01 15.9 15.1 0.17 12.0 0.2 4.6 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger Ferritin PF00210.24 RUS79582.1 - 1.3e-28 99.7 1.0 2e-28 99.1 1.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 RUS79582.1 - 2.9e-05 24.5 0.2 4e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Rubrerythrin Gly-zipper_YMGG PF13441.6 RUS79583.1 - 0.00032 20.4 7.0 0.00076 19.2 7.0 1.6 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 RUS79583.1 - 0.028 14.2 12.3 0.051 13.4 12.3 1.4 1 0 0 1 1 1 0 Glycine-zipper domain RTX PF02382.15 RUS79583.1 - 0.078 12.6 0.1 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein MccV PF17508.2 RUS79583.1 - 0.18 12.4 5.3 0.42 11.2 5.0 1.7 1 1 1 2 2 2 0 Microcin V bacteriocin Bacteriocin_IIc PF10439.9 RUS79583.1 - 0.3 11.2 10.0 0.73 10.0 10.0 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 RUS79583.1 - 0.87 9.9 9.7 1 9.6 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF456) PT-VENN PF04829.13 RUS79583.1 - 0.99 9.5 0.1 0.99 9.5 0.1 3.3 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 RUS79583.1 - 1.5 8.8 18.0 19 5.2 18.1 2.4 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 RUS79583.1 - 2.1 8.4 16.8 12 6.0 16.8 2.1 1 1 0 1 1 1 0 Glycine zipper Prominin PF05478.11 RUS79584.1 - 5.6e-76 256.2 15.1 1e-29 103.2 0.0 3.1 3 0 0 3 3 3 3 Prominin DUF2207 PF09972.9 RUS79584.1 - 6 5.5 20.7 4.3e+02 -0.6 0.2 3.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 RUS79585.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family HemY_N PF07219.13 RUS79585.1 - 0.013 15.7 0.4 0.018 15.3 0.4 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Shisa PF13908.6 RUS79585.1 - 0.025 14.9 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SieB PF14163.6 RUS79585.1 - 0.058 12.9 0.1 0.077 12.5 0.1 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B UPF0239 PF06783.11 RUS79585.1 - 0.16 12.2 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Fasciclin PF02469.22 RUS79586.1 - 1.2e-44 151.6 0.1 1.1e-23 83.8 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain DDRGK PF09756.9 RUS79587.1 - 9.9e-63 211.1 30.3 9.9e-63 211.1 30.3 1.6 2 0 0 2 2 2 1 DDRGK domain FeoC PF09012.10 RUS79587.1 - 0.00031 20.7 0.2 0.68 10.0 0.0 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator OAD_gamma PF04277.13 RUS79587.1 - 0.0026 18.3 6.0 0.0079 16.8 0.0 3.2 2 1 0 2 2 1 1 Oxaloacetate decarboxylase, gamma chain RR_TM4-6 PF06459.12 RUS79587.1 - 0.0076 16.1 15.3 0.0096 15.8 15.3 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.6 RUS79587.1 - 0.03 14.7 11.4 0.03 14.7 11.4 2.6 1 1 1 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Serinc PF03348.15 RUS79587.1 - 0.21 10.5 0.3 0.34 9.8 0.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.17 RUS79587.1 - 0.74 9.9 3.1 0.95 9.6 3.1 1.4 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 RUS79587.1 - 2.1 6.2 12.0 2.8 5.7 12.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 RUS79587.1 - 2.9 6.2 7.0 7.7 4.8 7.0 1.7 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4375 PF14300.6 RUS79587.1 - 5.8 7.2 14.6 1.9 8.8 10.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) HSP70 PF00012.20 RUS79587.1 - 7.4 4.6 19.0 10 4.2 19.0 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF3347 PF11827.8 RUS79587.1 - 7.4 6.7 13.9 14 5.9 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Amino_oxidase PF01593.24 RUS79588.1 - 8.7e-71 239.5 0.0 1.4e-70 238.9 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS79588.1 - 6.4e-13 48.7 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS79588.1 - 0.0013 18.4 0.4 0.0021 17.7 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RUS79588.1 - 0.0017 17.7 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS79588.1 - 0.0097 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS79588.1 - 0.052 12.6 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 RUS79588.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MORN PF02493.20 RUS79589.1 - 1.6e-41 137.7 72.5 8.3e-07 28.5 0.4 10.6 10 0 0 10 10 10 10 MORN repeat ICAP-1_inte_bdg PF10480.9 RUS79590.1 - 7.9e-24 84.8 0.6 9e-24 84.6 0.6 1.1 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 RUS79590.1 - 4.1e-13 49.6 1.1 7.1e-13 48.8 1.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS79590.1 - 0.021 15.0 0.6 0.064 13.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotyrosine-binding domain FtsK_SpoIIIE_N PF12538.8 RUS79590.1 - 0.028 14.6 0.7 0.1 12.8 0.3 2.0 1 1 1 2 2 2 0 DNA transporter DUF4172 PF13776.6 RUS79590.1 - 0.046 14.1 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) PSP PF04046.16 RUS79592.1 - 0.00013 21.8 2.1 0.63 10.0 0.1 3.7 2 2 0 2 2 2 2 PSP MRP_L53 PF10780.9 RUS79592.1 - 0.02 15.1 3.1 1.2 9.4 0.1 2.9 2 1 1 3 3 3 0 39S ribosomal protein L53/MRP-L53 Claudin_2 PF13903.6 RUS79593.1 - 3.4e-15 56.3 2.9 6.7e-15 55.3 2.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS79593.1 - 1.9e-10 40.9 3.8 0.00019 21.4 2.4 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 RUS79593.1 - 0.00048 19.8 11.2 0.0038 16.9 5.7 2.7 1 1 1 2 2 2 2 SUR7/PalI family DuoxA PF10204.9 RUS79593.1 - 0.1 11.6 8.4 0.048 12.7 0.5 2.4 2 1 1 3 3 3 0 Dual oxidase maturation factor SPG48 PF14764.6 RUS79594.1 - 9.3e-28 97.1 6.9 1.2e-27 96.8 2.4 2.9 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Svf1_C PF17187.4 RUS79594.1 - 0.12 12.1 0.4 2.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Svf1-like C-terminal lipocalin-like domain SUIM_assoc PF16619.5 RUS79598.1 - 0.4 10.8 7.6 0.074 13.1 3.4 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YL1 PF05764.13 RUS79599.1 - 0.00073 19.7 20.5 0.00073 19.7 20.5 2.5 2 1 0 2 2 1 1 YL1 nuclear protein CDC45 PF02724.14 RUS79599.1 - 0.14 10.4 26.4 0.019 13.3 21.8 1.7 2 0 0 2 2 2 0 CDC45-like protein DUF4637 PF15470.6 RUS79599.1 - 2.3 7.9 17.6 0.38 10.5 12.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 RUS79599.1 - 2.4 6.2 44.3 3.9 5.4 44.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 RUS79599.1 - 3.3 7.2 33.9 3.1 7.3 31.2 2.3 2 1 0 2 2 2 0 PPP4R2 Mpp10 PF04006.12 RUS79599.1 - 3.3 6.0 31.6 0.26 9.7 26.2 1.7 2 0 0 2 2 2 0 Mpp10 protein eIF-3c_N PF05470.12 RUS79599.1 - 3.5 5.8 13.9 0.37 9.1 9.7 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2722 PF10846.8 RUS79599.1 - 4 6.3 32.8 1.3 7.9 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) HSP90 PF00183.18 RUS79599.1 - 5.7 5.7 11.2 11 4.8 11.2 1.4 1 0 0 1 1 1 0 Hsp90 protein Roughex PF06020.11 RUS79599.1 - 5.8 5.9 28.7 5.9 5.9 20.6 2.3 2 0 0 2 2 2 0 Drosophila roughex protein DUF3295 PF11702.8 RUS79599.1 - 8.8 5.6 29.2 1.2 8.4 24.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF885 PF05960.11 RUS79600.1 - 1.3e-72 246.2 0.3 1.6e-72 245.8 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) ShK PF01549.24 RUS79601.1 - 2.7e-07 31.0 6.3 3.5e-07 30.6 5.8 1.5 1 1 0 1 1 1 1 ShK domain-like DUF5645 PF18713.1 RUS79601.1 - 0.0048 17.2 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5645) Adenylsucc_synt PF00709.21 RUS79602.1 - 1.3e-51 175.8 0.2 1.5e-51 175.7 0.2 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Vps39_1 PF10366.9 RUS79603.1 - 2.5e-31 108.1 2.1 2.5e-31 108.1 2.1 3.9 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 RUS79603.1 - 1.1e-29 103.0 3.4 3.1e-29 101.6 2.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 RUS79603.1 - 3.8e-27 95.6 0.0 9.3e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 RUS79603.1 - 1.4e-13 50.9 9.7 3.3e-05 23.8 0.0 4.9 5 1 0 5 5 5 3 Region in Clathrin and VPS TPR_12 PF13424.6 RUS79603.1 - 0.023 15.0 2.6 3.2 8.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2703 PF10865.8 RUS79603.1 - 2.2 8.5 5.1 0.68 10.1 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) Spectrin PF00435.21 RUS79604.1 - 2.4e-148 484.4 63.1 7.3e-23 81.1 4.4 8.3 8 0 0 8 8 8 8 Spectrin repeat CH PF00307.31 RUS79604.1 - 7.3e-49 164.5 2.5 9.8e-26 90.1 0.0 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS79604.1 - 2e-08 34.0 0.2 5.3e-06 26.2 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain SesA PF17107.5 RUS79604.1 - 0.02 15.1 4.2 0.73 10.0 0.4 3.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GIT_CC PF16559.5 RUS79604.1 - 0.039 13.8 4.8 1.1 9.1 0.2 3.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CH_2 PF06294.11 RUS79604.1 - 0.085 13.0 2.6 3.8 7.7 0.0 4.5 5 0 0 5 5 5 0 CH-like domain in sperm protein CnrY PF17524.2 RUS79604.1 - 2 8.7 4.6 29 5.0 0.2 3.5 3 0 0 3 3 3 0 Anti-sigma factor CnrY SseC PF04888.12 RUS79604.1 - 6 6.4 9.6 20 4.6 1.2 3.5 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family zf-C2H2 PF00096.26 RUS79605.1 - 1.2e-20 72.7 38.4 0.00046 20.5 0.5 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS79605.1 - 3e-16 58.7 39.0 0.0023 18.6 1.5 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS79605.1 - 8.4e-14 51.3 35.9 0.00059 20.1 1.8 6.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-met PF12874.7 RUS79605.1 - 0.0035 17.7 13.3 0.0038 17.6 1.0 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS79605.1 - 0.0043 17.3 1.4 0.0043 17.3 1.4 4.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 RUS79605.1 - 0.0048 17.1 19.8 1.7 8.8 1.2 4.6 2 1 1 4 4 4 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 RUS79605.1 - 0.017 15.4 16.3 1.6 9.1 5.0 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 RUS79605.1 - 0.036 14.1 1.7 0.036 14.1 1.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CGNR PF11706.8 RUS79605.1 - 0.2 11.5 14.0 4 7.4 0.1 5.3 5 0 0 5 5 5 0 CGNR zinc finger ARS2 PF04959.13 RUS79605.1 - 0.21 11.9 7.1 1.3 9.4 0.7 2.8 1 1 2 3 3 3 0 Arsenite-resistance protein 2 DUF629 PF04780.12 RUS79605.1 - 0.65 8.5 7.6 0.092 11.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 RUS79605.1 - 2.2 9.0 23.8 5.1 7.8 0.6 5.0 2 2 3 5 5 5 0 FOXP coiled-coil domain TFIIA PF03153.13 RUS79606.1 - 0.0071 16.4 11.7 0.0084 16.1 11.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 RUS79606.1 - 1.7 7.3 5.8 1.6 7.3 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCSAP PF15748.5 RUS79606.1 - 4.6 7.3 12.5 6.9 6.8 12.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated zf-C4 PF00105.18 RUS79607.1 - 4e-13 49.6 4.0 4e-13 49.6 4.0 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS79607.1 - 0.00027 20.6 0.0 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Ion_trans PF00520.31 RUS79609.1 - 8e-51 172.6 11.6 1e-50 172.3 11.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS79609.1 - 9.1e-28 96.5 0.1 1.6e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS79609.1 - 1.6e-13 50.4 5.6 1.6e-13 50.4 5.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 RUS79609.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF5056 PF16479.5 RUS79609.1 - 0.13 12.5 0.3 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Sigma_reg_N PF13800.6 RUS79609.1 - 1.8 8.9 5.8 4.3 7.7 0.1 3.6 4 0 0 4 4 4 0 Sigma factor regulator N-terminal YrhC PF14143.6 RUS79609.1 - 2.8 8.1 8.3 1.7 8.8 0.1 3.2 4 0 0 4 4 4 0 YrhC-like protein PKD_channel PF08016.12 RUS79609.1 - 3.3 6.3 11.3 0.023 13.4 2.0 2.0 2 1 1 3 3 3 0 Polycystin cation channel U1snRNP70_N PF12220.8 RUS79610.1 - 2.3e-28 98.7 6.6 2.7e-28 98.4 6.6 1.1 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2536 PF10750.9 RUS79611.1 - 2.8e-05 23.9 0.0 0.1 12.5 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2536) DUF4803 PF16061.5 RUS79611.1 - 0.032 13.7 0.3 0.13 11.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4803) SLY PF12485.8 RUS79611.1 - 6.2 7.5 14.5 7.2 7.3 0.6 3.1 2 1 1 3 3 3 0 Lymphocyte signaling adaptor protein Gti1_Pac2 PF09729.9 RUS79612.1 - 0.0012 18.9 10.7 0.0016 18.6 10.7 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Vfa1 PF08432.10 RUS79612.1 - 0.0015 18.9 25.9 0.002 18.5 25.9 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 LicD PF04991.13 RUS79612.1 - 0.0018 18.4 15.8 0.0023 18.1 15.8 1.1 1 0 0 1 1 1 1 LicD family DUF3807 PF12720.7 RUS79612.1 - 0.0019 18.5 17.4 0.0025 18.1 17.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) AAA_11 PF13086.6 RUS79612.1 - 0.0037 17.1 8.2 0.004 17.0 8.2 1.1 1 0 0 1 1 1 1 AAA domain V_ATPase_I PF01496.19 RUS79612.1 - 0.0038 15.2 7.2 0.0043 15.0 7.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 RUS79612.1 - 0.0049 16.7 17.4 0.0054 16.6 17.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 RUS79612.1 - 0.006 17.1 4.4 0.0073 16.8 4.4 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DDHD PF02862.17 RUS79612.1 - 0.0076 16.4 3.9 0.0076 16.4 3.9 1.1 1 0 0 1 1 1 1 DDHD domain DAG_kinase_N PF14513.6 RUS79612.1 - 0.0084 16.3 8.0 0.0096 16.1 8.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus CENP-N PF05238.13 RUS79612.1 - 0.0085 15.4 11.7 0.0095 15.3 11.7 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF2052 PF09747.9 RUS79612.1 - 0.013 15.7 5.4 0.013 15.6 5.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 RUS79612.1 - 0.014 14.4 11.5 0.015 14.3 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 RUS79612.1 - 0.015 14.3 12.0 0.016 14.2 12.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Tim54 PF11711.8 RUS79612.1 - 0.019 13.8 19.4 0.024 13.4 19.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3292 PF11696.8 RUS79612.1 - 0.023 13.1 12.6 0.028 12.8 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SRP-alpha_N PF04086.13 RUS79612.1 - 0.05 13.5 24.4 0.058 13.3 24.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2126 PF09899.9 RUS79612.1 - 0.051 11.6 3.9 0.052 11.6 3.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AF-4 PF05110.13 RUS79612.1 - 0.075 11.1 31.4 0.087 10.9 31.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CPSF100_C PF13299.6 RUS79612.1 - 0.085 13.0 11.9 0.11 12.7 11.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3530 PF12048.8 RUS79612.1 - 0.11 11.9 3.0 0.15 11.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Neur_chan_memb PF02932.16 RUS79612.1 - 0.11 12.5 8.7 0.12 12.4 8.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ORC_WH_C PF18137.1 RUS79612.1 - 0.13 12.4 11.3 0.2 11.7 11.3 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RNA_polI_A34 PF08208.11 RUS79612.1 - 0.13 12.3 52.4 0.2 11.8 52.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Histone PF00125.24 RUS79612.1 - 0.15 12.4 22.3 0.23 11.8 22.3 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3405 PF11885.8 RUS79612.1 - 0.15 10.6 9.9 0.18 10.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SpoIIP PF07454.11 RUS79612.1 - 0.16 11.4 18.3 0.21 11.0 18.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5308 PF17233.2 RUS79612.1 - 0.17 12.1 2.1 0.2 11.9 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF3527 PF12043.8 RUS79612.1 - 0.17 11.4 13.4 0.22 11.1 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF1764 PF08576.10 RUS79612.1 - 0.18 12.7 27.6 0.38 11.7 27.6 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 RUS79612.1 - 0.19 11.5 18.5 0.26 11.0 18.5 1.2 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 RUS79612.1 - 0.2 9.7 19.2 0.24 9.4 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 RUS79612.1 - 0.2 10.4 9.1 0.22 10.3 9.1 1.1 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 RUS79612.1 - 0.21 11.0 6.5 0.23 10.9 6.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin YL1 PF05764.13 RUS79612.1 - 0.21 11.7 31.4 0.3 11.2 31.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein OATP PF03137.20 RUS79612.1 - 0.22 9.8 14.4 0.29 9.4 14.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NPR3 PF03666.13 RUS79612.1 - 0.23 10.2 19.4 0.29 9.9 19.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4228 PF14009.6 RUS79612.1 - 0.27 11.6 10.2 0.18 12.2 8.5 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4228) NARP1 PF12569.8 RUS79612.1 - 0.3 10.0 30.4 0.35 9.7 30.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3408 PF11888.8 RUS79612.1 - 0.32 11.1 19.4 0.56 10.3 19.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4776 PF16003.5 RUS79612.1 - 0.39 9.7 27.9 0.48 9.4 27.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) MCM_bind PF09739.9 RUS79612.1 - 0.43 9.0 12.7 0.49 8.8 12.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor EOS1 PF12326.8 RUS79612.1 - 0.59 10.0 9.2 0.21 11.5 6.9 1.5 2 0 0 2 2 1 0 N-glycosylation protein Band_3_cyto PF07565.13 RUS79612.1 - 0.67 9.7 7.7 0.72 9.6 7.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 RUS79612.1 - 0.68 9.1 7.6 0.84 8.8 7.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4770 PF15994.5 RUS79612.1 - 0.69 10.1 22.5 1.7 8.9 22.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RNA_pol_Rpc4 PF05132.14 RUS79612.1 - 0.72 10.3 22.0 1.1 9.7 22.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 RUS79612.1 - 0.92 7.8 3.4 0.92 7.8 3.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1943 PF09172.11 RUS79612.1 - 1 8.6 13.1 1.2 8.4 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF913 PF06025.12 RUS79612.1 - 1 8.2 8.2 1.3 8.0 8.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Membralin PF09746.9 RUS79612.1 - 1.2 8.0 8.9 1.5 7.8 8.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein RPOL_N PF14700.6 RUS79612.1 - 2.1 7.7 20.0 2.7 7.3 20.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF1980 PF09323.10 RUS79612.1 - 2.7 7.9 10.0 3.9 7.4 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4834 PF16118.5 RUS79612.1 - 2.8 9.0 16.5 4.6 8.3 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 RUS79612.1 - 2.8 7.6 8.1 4.4 7.0 8.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF4614 PF15391.6 RUS79612.1 - 3.1 7.8 10.0 4.2 7.3 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Rtf2 PF04641.12 RUS79612.1 - 3.6 6.9 33.1 6.3 6.1 33.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_U57 PF05582.12 RUS79612.1 - 4.7 6.4 14.5 6.1 6.0 14.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4569 PF15133.6 RUS79612.1 - 5.7 6.6 12.6 7.2 6.2 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Sec62 PF03839.16 RUS79612.1 - 6.1 6.3 29.8 12 5.3 29.8 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Otopetrin PF03189.13 RUS79612.1 - 7.8 5.2 8.0 9.7 4.9 8.0 1.1 1 0 0 1 1 1 0 Otopetrin CLN3 PF02487.17 RUS79612.1 - 7.8 5.4 10.2 9.8 5.1 10.2 1.1 1 0 0 1 1 1 0 CLN3 protein Peroxin-13_N PF04088.13 RUS79612.1 - 7.9 6.8 11.0 12 6.2 11.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Folate_carrier PF01770.18 RUS79612.1 - 9.1 4.9 10.3 11 4.6 10.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier 7TM_GPCR_Srw PF10324.9 RUS79613.1 - 1.1e-32 113.6 20.3 1.5e-31 109.8 20.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS79613.1 - 2e-10 40.5 15.3 2.4e-06 27.1 6.7 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) SNARE_assoc PF09335.11 RUS79613.1 - 0.031 14.8 0.1 0.031 14.8 0.1 2.3 3 0 0 3 3 3 0 SNARE associated Golgi protein Fusion_gly PF00523.18 RUS79613.1 - 0.036 12.3 0.0 0.063 11.5 0.0 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 7tm_1 PF00001.21 RUS79615.1 - 0.0024 17.2 3.3 0.0024 17.2 3.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4731 PF15875.5 RUS79615.1 - 0.079 13.2 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) DUF4834 PF16118.5 RUS79615.1 - 0.37 11.8 5.0 0.14 13.1 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) AF-4 PF05110.13 RUS79615.1 - 1.3 7.0 9.6 1.7 6.6 9.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 7TM_GPCR_Srw PF10324.9 RUS79615.1 - 3.6 6.8 18.2 0.76 9.0 12.0 2.5 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw zf-H2C2_2 PF13465.6 RUS79616.1 - 1.7e-63 208.4 115.7 2.3e-07 30.9 0.4 14.7 15 0 0 15 15 14 13 Zinc-finger double domain zf-C2H2 PF00096.26 RUS79616.1 - 1.1e-50 167.3 140.9 2.3e-05 24.6 1.6 15.5 15 1 0 15 15 15 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS79616.1 - 1e-42 141.0 125.8 0.00031 21.3 1.2 15.2 15 0 0 15 15 15 14 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS79616.1 - 3.3e-22 78.0 114.5 0.00013 21.8 1.0 15.5 15 1 0 15 15 15 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS79616.1 - 2.9e-06 26.9 2.4 2.9e-06 26.9 2.4 12.0 13 4 0 13 13 11 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS79616.1 - 3.9e-06 26.5 9.7 0.00043 20.0 0.8 12.4 14 0 0 14 14 12 4 zinc-finger C2H2-type zf-Di19 PF05605.12 RUS79616.1 - 4.2e-06 27.0 75.6 0.0006 20.1 3.9 8.6 5 2 4 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 RUS79616.1 - 5.3e-06 26.2 39.3 0.066 13.1 0.1 10.2 9 3 3 12 12 11 3 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 RUS79616.1 - 7.3e-05 22.9 79.6 2.2 8.7 0.0 14.2 15 2 0 15 15 15 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS79616.1 - 0.00035 20.9 90.0 0.23 11.9 0.1 14.9 15 1 0 15 15 14 4 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 RUS79616.1 - 0.0048 16.7 19.4 0.62 9.9 0.6 6.0 6 0 0 6 6 6 2 Rad50 zinc hook motif Ta0938 PF11494.8 RUS79616.1 - 0.0063 16.8 24.9 0.58 10.5 0.1 6.3 3 2 5 8 8 7 2 Ta0938 zf-C2H2_8 PF15909.5 RUS79616.1 - 0.0099 16.2 2.1 0.0099 16.2 2.1 7.6 1 1 7 8 8 8 2 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 RUS79616.1 - 0.018 15.7 47.4 0.35 11.6 0.9 8.4 1 1 5 7 7 5 0 Zinc finger C2H2-type, 3 repeats FKBP_N_2 PF18023.1 RUS79616.1 - 0.051 13.7 0.0 37 4.5 0.0 3.5 3 0 0 3 3 3 0 BDBT FKBP like N-terminal zinc_ribbon_15 PF17032.5 RUS79616.1 - 0.061 14.1 55.6 1.8 9.4 3.3 8.0 2 1 5 9 9 9 0 zinc-ribbon family TRAF6_Z2 PF18048.1 RUS79616.1 - 0.1 12.7 0.5 0.1 12.7 0.5 9.7 13 0 0 13 13 9 0 TNF receptor-associated factor 6 zinc finger 2 PglL_A PF15864.5 RUS79616.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein glycosylation ligase zf-C2H2_2 PF12756.7 RUS79616.1 - 0.11 12.9 0.4 0.11 12.9 0.4 11.9 1 1 10 11 11 9 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS79616.1 - 0.11 12.7 65.3 3.2 7.9 0.3 10.6 6 3 5 11 11 10 0 Zinc ribbon domain Ion_trans_N PF08412.10 RUS79616.1 - 0.16 11.6 4.1 3.3 7.4 0.1 2.9 3 0 0 3 3 2 0 Ion transport protein N-terminal zf-WRNIP1_ubi PF18279.1 RUS79616.1 - 0.53 11.0 18.7 18 6.3 0.3 6.7 6 0 0 6 6 5 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf_UBZ PF18439.1 RUS79616.1 - 0.55 9.9 0.0 0.55 9.9 0.0 13.2 15 0 0 15 15 15 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 RUS79616.1 - 2.3 8.3 50.0 1.7 8.7 0.9 7.9 1 1 6 7 7 7 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BolA PF01722.18 RUS79616.1 - 4.7 7.6 15.9 7.2 7.0 0.2 5.5 3 3 3 6 6 6 0 BolA-like protein Eclosion PF04736.12 RUS79616.1 - 5.7 6.7 11.6 9.4 6.0 0.7 3.9 3 0 0 3 3 3 0 Eclosion hormone DUF3268 PF11672.8 RUS79616.1 - 6.6 7.1 46.0 0.29 11.5 0.8 7.2 6 1 0 7 7 7 0 zinc-finger-containing domain Zn-C2H2_12 PF18112.1 RUS79616.1 - 8.5 6.9 46.2 1.4 9.4 0.6 10.1 12 0 0 12 12 12 0 Autophagy receptor zinc finger-C2H2 domain Pyridoxal_deC PF00282.19 RUS79617.1 - 1.2e-23 83.4 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain TIMP PF00965.17 RUS79618.1 - 3.1e-09 36.9 0.5 3.7e-09 36.6 0.5 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Hep_59 PF07052.11 RUS79622.1 - 1.7e-30 105.9 6.9 1.7e-30 105.9 6.9 2.5 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 EloA-BP1 PF15870.5 RUS79622.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.0 2 1 1 3 3 3 0 ElonginA binding-protein 1 LcrG PF07216.12 RUS79622.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.5 3 0 0 3 3 3 0 LcrG protein TAF8_C PF10406.9 RUS79623.1 - 0.74 10.4 14.2 9.3 6.9 0.7 4.8 2 2 2 4 4 4 0 Transcription factor TFIID complex subunit 8 C-term NUC129 PF08157.11 RUS79623.1 - 7.7 7.0 8.2 1.8 9.0 0.3 3.3 3 0 0 3 3 3 0 NUC129 domain Homeodomain PF00046.29 RUS79624.1 - 2.2e-23 81.9 5.7 4.5e-23 80.9 5.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS79624.1 - 0.011 15.6 0.2 0.031 14.2 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_28 PF13518.6 RUS79624.1 - 0.056 13.6 0.1 0.21 11.7 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain DNA_pol_phi PF04931.13 RUS79625.1 - 0.00079 17.7 29.2 0.001 17.3 29.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RUS79625.1 - 0.00094 17.5 13.8 0.0012 17.2 13.8 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS79625.1 - 0.0011 18.5 11.7 0.0014 18.1 11.7 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 RUS79625.1 - 0.0024 16.2 8.2 0.0024 16.2 8.2 1.5 2 0 0 2 2 2 1 CDC45-like protein Cu_amine_oxidN3 PF02728.16 RUS79625.1 - 0.13 12.7 0.1 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain TFIIA PF03153.13 RUS79625.1 - 0.15 12.1 22.1 0.25 11.3 22.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 RUS79625.1 - 0.2 11.0 13.1 0.29 10.5 13.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.11 RUS79625.1 - 0.28 10.8 14.4 0.41 10.2 14.4 1.3 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 RUS79625.1 - 0.31 10.9 4.6 0.42 10.4 4.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 RUS79625.1 - 0.44 8.9 12.7 0.58 8.5 12.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Sigma70_ner PF04546.13 RUS79625.1 - 0.48 10.3 13.9 0.86 9.4 13.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 RUS79625.1 - 0.52 9.6 16.0 0.73 9.1 16.0 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 RUS79625.1 - 0.59 10.2 16.7 0.87 9.7 16.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Rhabdo_ncap PF00945.18 RUS79625.1 - 0.93 8.3 6.3 1.4 7.7 6.3 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TFB6 PF17110.5 RUS79625.1 - 2.9 7.6 8.6 4.8 6.9 8.6 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2076 PF09849.9 RUS79625.1 - 3.9 7.4 22.3 7.1 6.6 22.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) EGF PF00008.27 RUS79627.1 - 6.2e-23 80.8 36.9 1.4e-08 34.9 9.7 3.7 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 RUS79627.1 - 1.5e-13 50.8 37.2 8.6e-06 26.2 4.4 4.2 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS79627.1 - 4.8e-05 23.6 41.9 0.11 12.8 7.7 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_CA PF07645.15 RUS79627.1 - 0.0027 17.9 40.6 0.38 11.0 6.3 3.6 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS79627.1 - 0.93 9.8 31.3 3 8.2 7.2 3.6 1 1 2 3 3 3 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 RUS79627.1 - 4.1 7.7 34.5 2.2 8.5 6.8 3.8 3 1 0 3 3 3 0 EGF domain DUF4595 PF15283.6 RUS79628.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold SH3_2 PF07653.17 RUS79630.1 - 5.4e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Filament PF00038.21 RUS79630.1 - 0.0013 18.4 68.6 0.0014 18.3 30.9 3.6 1 1 2 3 3 3 3 Intermediate filament protein SH3_1 PF00018.28 RUS79630.1 - 0.005 16.4 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 SH3 domain LPP PF04728.13 RUS79630.1 - 0.095 13.1 11.1 0.28 11.6 0.1 4.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Pkinase PF00069.25 RUS79631.1 - 3.5e-77 259.3 0.0 4.2e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79631.1 - 2.7e-33 115.4 0.0 6.1e-32 110.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS79631.1 - 0.00044 19.3 0.4 0.0013 17.8 0.4 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS79631.1 - 0.021 14.1 0.1 2.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Kinase-like Sep15_SelM PF08806.11 RUS79631.1 - 0.031 14.4 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain APH PF01636.23 RUS79631.1 - 0.042 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RUS79631.1 - 0.071 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RUS79631.1 - 0.1 12.0 0.8 0.22 10.9 0.8 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-U PF13097.6 RUS79631.1 - 2.5 8.0 5.1 0.72 9.8 2.1 1.6 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit BRO1 PF03097.18 RUS79632.1 - 7.6e-35 120.4 0.2 9e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain Ribosomal_L14 PF00238.19 RUS79633.1 - 2.3e-15 56.8 0.1 3.7e-15 56.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e YscJ_FliF PF01514.17 RUS79633.1 - 0.024 14.3 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family dCMP_cyt_deam_1 PF00383.23 RUS79634.1 - 6.2e-19 67.8 0.0 9.8e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RUS79634.1 - 2.7e-10 40.1 0.5 4.6e-09 36.1 0.5 2.2 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 RUS79634.1 - 0.062 13.4 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase Neurokinin_B PF03823.14 RUS79635.1 - 0.81 9.8 3.7 18 5.4 0.2 2.5 2 0 0 2 2 2 0 Neurokinin B zf-GRF PF06839.12 RUS79635.1 - 4.4 7.5 13.4 3.6 7.7 0.1 3.7 4 0 0 4 4 4 0 GRF zinc finger CBM_14 PF01607.24 RUS79636.1 - 1.2e-55 185.5 80.9 2.4e-10 40.4 5.8 6.5 6 0 0 6 6 6 6 Chitin binding Peritrophin-A domain DUF2724 PF10893.8 RUS79636.1 - 0.13 12.1 0.3 14 5.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2724) MFS_1 PF07690.16 RUS79637.1 - 5.9e-26 91.2 18.2 3.9e-23 81.9 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2798 PF11391.8 RUS79639.1 - 0.00038 20.4 22.7 0.0015 18.6 8.5 3.1 2 2 1 3 3 3 3 Protein of unknown function (DUF2798) FeoB_C PF07664.12 RUS79639.1 - 0.95 9.2 14.9 1.9 8.2 1.4 3.3 2 2 1 3 3 3 0 Ferrous iron transport protein B C terminus ECF_trnsprt PF12822.7 RUS79639.1 - 2.5 8.1 12.7 4.6 7.3 12.7 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component 7tm_2 PF00002.24 RUS79641.1 - 5e-44 150.4 15.1 6.4e-44 150.1 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS79641.1 - 9e-16 58.1 3.9 2e-15 57.0 3.9 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Shisa PF13908.6 RUS79641.1 - 0.0014 18.9 1.5 0.01 16.1 0.5 2.2 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator VirB3 PF05101.13 RUS79641.1 - 6.3 7.1 14.5 0.27 11.5 1.0 3.6 3 1 1 4 4 4 0 Type IV secretory pathway, VirB3-like protein Zip PF02535.22 RUS79643.1 - 6.8 5.8 4.8 67 2.5 5.6 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter 7tm_1 PF00001.21 RUS79644.1 - 4.1e-27 95.1 15.9 3.2e-19 69.3 9.2 2.5 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) OSTbeta PF15048.6 RUS79644.1 - 0.061 13.5 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PIRT PF15099.6 RUS79644.1 - 0.14 11.8 0.8 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family 7tm_4 PF13853.6 RUS79644.1 - 0.82 9.3 27.4 0.82 9.3 8.8 3.4 3 1 0 3 3 3 0 Olfactory receptor EF-hand_1 PF00036.32 RUS79645.1 - 1.9e-17 61.4 8.9 0.009 15.5 0.0 7.4 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.6 RUS79645.1 - 2.1e-14 53.7 15.2 1.7e-05 25.2 0.3 4.6 4 1 2 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 RUS79645.1 - 7.2e-14 50.5 8.8 0.03 14.2 0.0 6.8 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 RUS79645.1 - 1.2e-13 50.7 10.7 0.0014 18.5 0.1 6.4 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 RUS79645.1 - 5.4e-12 44.6 7.2 0.036 13.6 0.0 7.2 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.9 RUS79645.1 - 0.0028 17.9 9.8 0.097 13.0 0.1 4.0 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Nbs1_C PF08599.10 RUS79645.1 - 0.015 15.4 1.2 0.055 13.6 1.2 2.0 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 NIBRIN_BRCT_II PF16508.5 RUS79645.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein DEAD PF00270.29 RUS79646.1 - 2.5e-28 99.0 0.2 4.1e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS79646.1 - 1.3e-24 86.7 0.1 2.9e-23 82.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RUS79646.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RUS79646.1 - 0.037 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2890 PF11081.8 RUS79647.1 - 0.025 14.7 0.3 0.046 13.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Peptidase_S64 PF08192.11 RUS79648.1 - 1.3 7.4 25.0 1.6 7.1 25.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4746 PF15928.5 RUS79648.1 - 4.8 6.5 23.1 0.83 9.0 16.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CBM_14 PF01607.24 RUS79649.1 - 1.1e-24 86.3 26.1 1.3e-10 41.2 3.5 3.5 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain AAA_18 PF13238.6 RUS79650.1 - 9.1e-28 97.4 0.1 2e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS79650.1 - 4.6e-05 23.7 0.0 7.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RUS79650.1 - 0.00019 21.9 0.2 0.00053 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 RUS79650.1 - 0.00024 21.3 0.0 0.00033 20.8 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family SKI PF01202.22 RUS79650.1 - 0.00036 20.7 0.4 0.0021 18.2 0.4 2.3 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 RUS79650.1 - 0.00092 19.4 0.1 0.0043 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RUS79650.1 - 0.00098 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 RUS79650.1 - 0.0017 18.8 0.6 0.0042 17.5 0.2 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS79650.1 - 0.0038 17.6 0.2 0.0065 16.9 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 RUS79650.1 - 0.0087 15.8 0.4 0.045 13.5 0.1 2.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 RUS79650.1 - 0.0087 16.3 0.4 0.03 14.6 0.2 2.0 2 1 0 2 2 2 1 AAA domain ADK PF00406.22 RUS79650.1 - 0.011 15.9 0.2 0.2 11.8 0.1 2.1 2 1 0 2 2 2 0 Adenylate kinase dNK PF01712.19 RUS79650.1 - 0.011 15.6 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 RUS79650.1 - 0.011 15.7 0.2 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 RUS79650.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family BTB_3 PF16017.5 RUS79650.1 - 0.019 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain RNA_helicase PF00910.22 RUS79650.1 - 0.02 15.3 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MCM PF00493.23 RUS79650.1 - 0.025 13.7 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain MMR_HSR1 PF01926.23 RUS79650.1 - 0.026 14.6 0.0 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ribosomal_S3Ae PF01015.18 RUS79650.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family DUF815 PF05673.13 RUS79650.1 - 0.038 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 RUS79650.1 - 0.044 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 RUS79650.1 - 0.056 12.7 0.2 0.16 11.2 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 RUS79650.1 - 0.079 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATPase PF06745.13 RUS79650.1 - 0.1 11.9 0.2 0.23 10.8 0.1 1.6 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 RUS79650.1 - 0.1 12.3 0.1 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FliM PF02154.15 RUS79650.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM PerC PF06069.11 RUS79650.1 - 0.14 12.4 0.0 2 8.7 0.0 2.1 2 0 0 2 2 2 0 PerC transcriptional activator AAA_29 PF13555.6 RUS79650.1 - 0.16 11.8 0.3 0.3 10.9 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RUS79650.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RUS79650.1 - 0.17 11.8 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 NTPase Ig_2 PF13895.6 RUS79651.1 - 2.3e-32 111.2 20.3 1.6e-07 31.6 0.1 6.5 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.6 RUS79651.1 - 3e-27 95.0 21.1 6.2e-06 26.7 0.1 7.0 6 1 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 RUS79651.1 - 7.7e-17 61.3 20.8 9.1e-05 22.6 0.3 7.2 6 2 0 6 6 6 4 Immunoglobulin domain Ig_4 PF16680.5 RUS79651.1 - 5.1e-13 49.1 6.5 0.00087 19.5 0.1 6.0 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS79651.1 - 8.9e-11 42.1 9.1 0.00017 21.9 0.1 6.2 5 1 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain I-set PF07679.16 RUS79651.1 - 1.7e-10 40.8 7.7 0.0085 16.1 0.1 6.1 5 2 0 5 5 5 4 Immunoglobulin I-set domain V-set PF07686.17 RUS79651.1 - 1.1e-09 38.4 18.9 0.095 12.9 0.0 9.0 6 5 3 9 9 9 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS79651.1 - 4e-06 26.8 0.2 0.95 9.6 0.1 4.9 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS79651.1 - 0.0088 15.6 5.9 0.67 9.6 0.0 4.7 6 0 0 6 6 6 1 Immunoglobulin domain EGF_CA PF07645.15 RUS79651.1 - 0.013 15.7 3.5 0.013 15.7 3.5 4.0 3 1 0 3 3 3 0 Calcium-binding EGF domain DUF5391 PF17369.2 RUS79651.1 - 0.092 12.8 0.2 10 6.2 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5391) zf-RING_2 PF13639.6 RUS79652.1 - 6.8e-13 48.7 13.6 6.8e-13 48.7 13.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RUS79652.1 - 2.1e-10 40.7 9.1 4e-10 39.8 9.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 RUS79652.1 - 9.4e-09 34.9 6.4 9.4e-09 34.9 6.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS79652.1 - 2.2e-08 33.8 12.9 4e-08 33.0 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS79652.1 - 2.6e-06 27.3 12.7 2.6e-06 27.3 12.7 1.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS79652.1 - 4.2e-06 26.5 13.1 7.9e-06 25.6 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79652.1 - 1.5e-05 24.7 10.9 2.6e-05 24.0 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS79652.1 - 2.5e-05 24.2 5.7 2.5e-05 24.2 5.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RUS79652.1 - 8.4e-05 22.6 7.3 0.00013 22.0 7.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 RUS79652.1 - 0.0011 18.8 10.7 0.0012 18.7 5.9 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 RUS79652.1 - 0.0026 17.8 4.9 0.0037 17.3 4.9 1.2 1 0 0 1 1 1 1 KIAA1045 RING finger Prok-RING_4 PF14447.6 RUS79652.1 - 0.0027 17.5 11.1 0.0049 16.7 11.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS79652.1 - 0.0079 16.0 10.3 0.0079 16.0 10.3 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RUS79652.1 - 0.0091 15.6 11.6 0.027 14.1 11.7 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RUS79652.1 - 0.039 14.1 16.1 0.22 11.7 11.9 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain PHD PF00628.29 RUS79652.1 - 0.9 9.5 11.3 3.1 7.8 11.3 1.9 1 1 1 2 2 2 0 PHD-finger RINGv PF12906.7 RUS79652.1 - 0.99 9.6 17.9 0.099 12.8 13.5 1.6 2 0 0 2 2 2 0 RING-variant domain Rtf2 PF04641.12 RUS79652.1 - 1.8 7.9 6.9 5.7 6.2 6.8 1.6 1 1 1 2 2 2 0 Rtf2 RING-finger zf-P11 PF03854.14 RUS79652.1 - 4.7 6.9 14.7 2 8.1 11.8 1.9 1 1 1 2 2 2 0 P-11 zinc finger PA PF02225.22 RUS79653.1 - 1.3e-10 41.1 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 PA domain adh_short PF00106.25 RUS79654.1 - 4.4e-09 36.1 0.1 6.9e-09 35.4 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS79654.1 - 3e-08 33.5 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RUS79654.1 - 0.0026 17.3 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LRR_8 PF13855.6 RUS79656.1 - 2.1e-07 30.6 0.5 4.1e-07 29.7 0.5 1.5 1 0 0 1 1 1 1 Leucine rich repeat Ig_3 PF13927.6 RUS79656.1 - 1e-06 29.2 0.8 6.4e-06 26.7 0.1 2.4 1 1 1 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RUS79656.1 - 1.6e-05 24.9 0.1 3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 RUS79656.1 - 3.7e-05 23.8 0.7 3.7e-05 23.8 0.7 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS79656.1 - 0.0001 22.5 0.2 0.00035 20.8 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 RUS79656.1 - 0.0017 18.7 0.1 0.0053 17.1 0.1 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) HRM PF02793.22 RUS79656.1 - 0.0034 17.7 0.4 0.008 16.5 0.4 1.6 1 0 0 1 1 1 1 Hormone receptor domain LRR_8 PF13855.6 RUS79657.1 - 0.0019 17.9 0.2 0.0029 17.3 0.2 1.3 1 0 0 1 1 1 1 Leucine rich repeat VWA_2 PF13519.6 RUS79658.1 - 2.5e-20 73.1 0.4 9.3e-20 71.3 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 RUS79658.1 - 5.5e-07 29.6 0.3 9.6e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 RUS79658.1 - 1.9e-05 24.3 4.3 0.0029 17.4 0.3 3.6 4 0 0 4 4 4 2 Ubiquitin interaction motif RAP80_UIM PF18282.1 RUS79658.1 - 0.081 12.7 0.4 0.081 12.7 0.4 4.1 3 1 1 4 4 4 0 RAP80 N-terminal ubiquitin interaction motif Myosin_head PF00063.21 RUS79659.1 - 2.4e-222 739.9 10.0 1.8e-190 634.6 6.5 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) RA PF00788.23 RUS79659.1 - 7.4e-07 29.7 0.0 4.8e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Ras association (RalGDS/AF-6) domain AAA_22 PF13401.6 RUS79659.1 - 0.00015 22.0 0.0 0.0059 16.9 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RUS79659.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 RUS79659.1 - 0.007 15.5 0.1 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein IQ PF00612.27 RUS79660.1 - 1.2e-06 27.8 8.6 0.0053 16.4 2.0 3.3 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF3899 PF13038.6 RUS79660.1 - 1.4 9.4 4.4 18 5.9 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) RhoGAP PF00620.27 RUS79661.1 - 2.2e-45 154.2 1.1 4.1e-45 153.3 0.0 2.0 3 0 0 3 3 3 1 RhoGAP domain CAP-ZIP_m PF15255.6 RUS79661.1 - 1.5e-05 25.3 0.5 0.00011 22.5 0.1 2.3 2 0 0 2 2 2 1 WASH complex subunit CAP-Z interacting, central region BUD22 PF09073.10 RUS79661.1 - 0.021 14.2 7.4 0.028 13.8 7.4 1.1 1 0 0 1 1 1 0 BUD22 ELH PF02323.15 RUS79661.1 - 0.046 13.1 2.2 0.077 12.4 2.2 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor Cwf_Cwc_15 PF04889.12 RUS79661.1 - 0.092 12.5 14.6 0.15 11.8 14.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4746 PF15928.5 RUS79661.1 - 1.6 8.1 8.8 4.7 6.5 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CAF1A PF12253.8 RUS79661.1 - 2 8.7 10.3 5.5 7.2 10.3 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Pox_Ag35 PF03286.14 RUS79661.1 - 4.1 7.1 12.6 2.3 8.0 9.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein V_ATPase_I PF01496.19 RUS79661.1 - 5.4 4.8 4.3 56 1.4 6.2 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 RUS79662.1 - 1.1e-19 70.3 10.0 1.3e-19 70.1 10.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4479 PF14794.6 RUS79662.1 - 0.00089 19.1 0.6 0.0018 18.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) KASH_CCD PF14662.6 RUS79662.1 - 0.0011 18.8 7.1 0.0015 18.4 7.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 RUS79662.1 - 0.0038 15.5 7.8 0.0046 15.2 7.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ADIP PF11559.8 RUS79662.1 - 0.022 14.9 7.0 0.34 11.0 2.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DDE_Tnp_ISL3 PF01610.17 RUS79662.1 - 0.022 14.5 1.5 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Transposase VWA_2 PF13519.6 RUS79662.1 - 0.025 15.2 0.2 0.038 14.6 0.1 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain PI3K_P85_iSH2 PF16454.5 RUS79662.1 - 0.043 13.4 9.4 0.28 10.8 9.5 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5320 PF17253.2 RUS79662.1 - 0.045 14.8 2.7 0.067 14.3 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF2968 PF11180.8 RUS79662.1 - 0.046 13.4 7.2 2.4 7.8 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4618 PF15397.6 RUS79662.1 - 0.068 12.6 8.4 0.29 10.5 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 RUS79662.1 - 0.069 13.5 1.6 0.069 13.5 1.6 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PBS_linker_poly PF00427.21 RUS79662.1 - 0.073 13.1 2.9 0.097 12.7 0.9 1.9 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide DUF1515 PF07439.11 RUS79662.1 - 0.15 12.1 0.5 0.23 11.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) CENP-F_leu_zip PF10473.9 RUS79662.1 - 0.42 10.6 9.6 0.89 9.6 9.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5595 PF18077.1 RUS79662.1 - 0.99 9.5 7.1 0.33 11.1 2.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) LMBR1 PF04791.16 RUS79662.1 - 1.4 7.7 3.9 1.6 7.6 3.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 RUS79662.1 - 1.4 8.1 8.1 3.9 6.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 RUS79662.1 - 3.8 7.8 8.8 7.1 6.9 2.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ank_2 PF12796.7 RUS79663.1 - 1.8e-28 99.0 2.2 1e-16 61.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS79663.1 - 4.2e-23 81.4 6.4 8.5e-10 39.0 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS79663.1 - 1.7e-21 75.6 11.5 0.00012 22.4 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS79663.1 - 1.8e-20 72.8 9.2 8.7e-08 32.3 0.3 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79663.1 - 7.5e-20 68.9 8.3 5.2e-05 23.3 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat SOCS_box PF07525.16 RUS79664.1 - 1.3e-07 31.9 0.8 3.3e-07 30.5 0.8 1.8 1 0 0 1 1 1 1 SOCS box RepA_C PF04796.12 RUS79664.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Plasmid encoded RepA protein Ank_3 PF13606.6 RUS79665.1 - 1.8e-15 55.5 0.2 0.011 16.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 RUS79665.1 - 7e-14 52.0 0.0 3.3e-06 27.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS79665.1 - 8.1e-14 52.0 0.0 3.6e-11 43.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS79665.1 - 9.4e-14 51.1 0.4 0.00059 20.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS79665.1 - 1.6e-10 41.0 0.1 0.0053 17.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SAICAR_synt PF01259.18 RUS79667.1 - 8.1e-43 146.8 0.2 2.4e-22 79.8 0.1 2.1 2 0 0 2 2 2 2 SAICAR synthetase AIRC PF00731.20 RUS79667.1 - 2.2e-41 140.9 0.0 3.3e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 AIR carboxylase Pkinase PF00069.25 RUS79668.1 - 3e-32 112.0 0.0 3.6e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79668.1 - 8.3e-09 35.1 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS79668.1 - 0.021 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DCX PF03607.17 RUS79669.1 - 1.4e-35 121.1 0.4 5.8e-19 68.0 0.0 2.5 2 0 0 2 2 2 2 Doublecortin DUF1598 PF07643.11 RUS79670.1 - 4.5e-05 23.6 0.0 3.7 7.9 0.0 3.5 1 1 2 4 4 4 2 Protein of unknown function (DUF1598) DUF4219 PF13961.6 RUS79670.1 - 9.2e-05 22.0 13.9 2.1 8.1 0.2 6.6 1 1 7 8 8 8 3 Domain of unknown function (DUF4219) RBD PF02196.15 RUS79670.1 - 0.0003 20.8 2.4 4.5 7.4 0.1 3.3 1 1 2 3 3 3 2 Raf-like Ras-binding domain RPN5_C PF18098.1 RUS79670.1 - 0.11 12.7 23.5 67 3.7 0.7 8.3 7 1 2 9 9 9 0 26S proteasome regulatory subunit RPN5 C-terminal domain DUF720 PF05302.11 RUS79670.1 - 0.12 12.2 1.6 7.5 6.4 0.3 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF720) TPKR_C2 PF16920.5 RUS79670.1 - 2.3 8.4 10.8 53 4.1 0.1 4.4 1 1 6 7 7 7 0 Tyrosine-protein kinase receptor C2 Ig-like domain NB-LRR PF12061.8 RUS79670.1 - 4.4 6.5 9.9 11 5.3 1.7 2.8 1 1 2 3 3 3 0 Late blight resistance protein R1 HALZ PF02183.18 RUS79671.1 - 0.012 15.8 23.3 0.052 13.8 2.5 5.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper Atg14 PF10186.9 RUS79671.1 - 0.046 12.8 30.8 0.049 12.7 4.5 3.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2408 PF10303.9 RUS79671.1 - 3.1 8.4 18.7 0.027 15.1 1.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) bZIP_1 PF00170.21 RUS79671.1 - 8 6.7 30.6 3.4 7.8 0.5 5.8 5 1 1 6 6 6 0 bZIP transcription factor 7tm_1 PF00001.21 RUS79672.1 - 9.9 5.4 15.5 56 2.9 15.5 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pirin_C PF05726.13 RUS79679.1 - 9.3e-25 87.0 0.0 6.2e-24 84.3 0.0 2.2 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 RUS79679.1 - 3.1e-12 46.4 0.2 7.1e-06 26.0 0.1 2.5 1 1 1 2 2 2 2 Pirin Yae1_N PF09811.9 RUS79681.1 - 0.2 11.4 15.1 11 5.9 0.2 4.6 2 2 2 4 4 4 0 Essential protein Yae1, N terminal OMP_b-brl_2 PF13568.6 RUS79681.1 - 0.77 9.8 15.8 1.4e+02 2.4 0.1 3.5 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain Keratin_2_head PF16208.5 RUS79681.1 - 0.88 9.7 12.4 2.2e+02 1.9 12.4 2.5 1 1 0 1 1 1 0 Keratin type II head MspA PF09203.11 RUS79681.1 - 3.7 7.4 17.3 6.2e+03 -3.1 17.3 3.2 1 1 0 1 1 1 0 MspA zf-C2H2 PF00096.26 RUS79682.1 - 6.3e-15 54.7 21.9 9.4e-06 25.8 1.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS79682.1 - 7.9e-11 41.9 23.6 1.7e-07 31.4 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS79682.1 - 4e-07 30.3 19.3 0.0057 17.4 1.2 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS79682.1 - 0.034 14.2 0.5 0.034 14.2 0.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 RUS79682.1 - 0.14 12.6 4.0 0.98 9.9 0.2 3.3 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 RUS79682.1 - 2.6 8.1 9.0 7 6.8 0.3 3.0 3 0 0 3 3 3 0 Aberrant zinc-finger Cwf_Cwc_15 PF04889.12 RUS79683.1 - 0.00069 19.4 6.8 0.00092 19.0 6.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RUS79683.1 - 0.0013 18.1 8.7 0.0016 17.8 8.7 1.1 1 0 0 1 1 1 1 NOA36 protein DUF2457 PF10446.9 RUS79683.1 - 0.044 12.9 15.3 0.051 12.7 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 RUS79683.1 - 0.081 13.2 11.8 0.11 12.8 11.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC15 PF15243.6 RUS79683.1 - 0.47 10.9 8.4 0.73 10.3 8.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.11 RUS79683.1 - 1.9 8.5 5.1 2.3 8.2 5.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 RUS79683.1 - 2.5 6.3 5.1 2.9 6.1 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 RUS79683.1 - 7.3 6.5 10.3 9.5 6.2 10.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FANCF PF11107.8 RUS79684.1 - 3.9e-16 59.2 2.9 5e-16 58.8 2.9 1.0 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Pre-PUA PF17832.1 RUS79685.1 - 6.4e-26 90.9 0.0 1.3e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RUS79685.1 - 1.1e-18 67.0 0.0 1.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain Methyltransf_11 PF08241.12 RUS79686.1 - 4.8e-10 40.0 0.0 6.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS79686.1 - 5.2e-07 29.7 0.0 6.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS79686.1 - 1.7e-05 25.4 0.0 2.4e-05 25.0 0.0 1.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS79686.1 - 3.6e-05 24.4 0.0 4.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS79686.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS79686.1 - 0.0087 15.4 0.0 0.0099 15.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-RING_14 PF17978.1 RUS79686.1 - 0.071 13.5 0.3 0.12 12.9 0.0 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain MetW PF07021.12 RUS79686.1 - 0.079 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 RUS79687.1 - 1.2e-15 57.9 0.0 2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS79687.1 - 1.3e-15 57.7 0.0 1.8e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS79687.1 - 1.4e-10 41.7 0.0 2.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS79687.1 - 4.7e-09 36.9 0.0 7.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS79687.1 - 8.5e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS79687.1 - 3.4e-08 33.1 0.0 1.7e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 RUS79687.1 - 0.0079 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 RUS79687.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ependymin PF00811.18 RUS79689.1 - 5.8e-07 29.8 0.0 9.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ependymin Ependymin PF00811.18 RUS79690.1 - 3.8e-07 30.4 0.0 1.5e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Ependymin DUF5422 PF17459.2 RUS79690.1 - 0.058 13.6 4.0 0.9 9.7 0.5 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5422) ESSS PF10183.9 RUS79690.1 - 0.2 11.9 0.5 5 7.4 0.0 2.2 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2369 PF10179.9 RUS79691.1 - 3.7e-11 43.3 0.0 7.6e-07 29.4 0.0 3.4 3 0 0 3 3 3 3 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 RUS79691.1 - 0.0009 19.5 0.1 0.011 16.0 0.0 3.0 3 1 0 3 3 3 1 Fibronectin type III domain InvH PF04741.12 RUS79692.1 - 0.024 14.6 2.1 0.38 10.7 0.7 2.1 1 1 1 2 2 2 0 InvH outer membrane lipoprotein LIM PF00412.22 RUS79694.1 - 9.4e-17 61.0 2.1 2e-16 60.0 2.1 1.5 1 0 0 1 1 1 1 LIM domain G-alpha PF00503.20 RUS79694.1 - 4.1e-08 32.8 0.0 5.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Ploopntkinase3 PF18751.1 RUS79694.1 - 0.032 14.2 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RUS79694.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS79694.1 - 0.095 13.2 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 RUS79694.1 - 0.13 12.5 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 RUS79694.1 - 0.18 12.2 0.1 0.28 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 RUS79697.1 - 2 8.8 9.1 22 5.5 0.1 2.4 1 1 1 2 2 2 0 EGF-like domain TSSC4 PF15264.6 RUS79698.1 - 1.1e-18 67.7 4.2 1.1e-18 67.7 4.2 2.2 2 1 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 eIF3_N PF09440.10 RUS79698.1 - 0.085 13.3 1.3 3.3 8.2 0.0 2.8 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain RbpA PF13397.6 RUS79698.1 - 0.19 12.4 2.7 1.2 9.8 0.7 2.5 2 0 0 2 2 2 0 RNA polymerase-binding protein PD-C2-AF1 PF09310.10 RUS79699.1 - 0.1 12.0 0.6 0.24 10.8 0.5 1.6 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 WD40 PF00400.32 RUS79699.1 - 0.22 12.5 5.6 1.1 10.3 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat FliG_M PF14841.6 RUS79701.1 - 0.021 15.0 2.2 0.88 9.8 1.3 2.5 1 1 1 2 2 2 0 FliG middle domain MgtE_N PF03448.17 RUS79701.1 - 0.031 14.9 0.2 0.069 13.8 0.2 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Kelch_1 PF01344.25 RUS79702.1 - 0.11 12.1 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 Kelch motif CS PF04969.16 RUS79703.1 - 0.00014 22.8 0.0 0.00026 22.0 0.0 1.4 1 1 0 1 1 1 1 CS domain SAM_PNT PF02198.16 RUS79704.1 - 4.2e-05 23.4 0.9 6.5e-05 22.8 0.9 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ets PF00178.22 RUS79705.1 - 1e-25 90.0 0.4 1.8e-25 89.2 0.4 1.4 1 0 0 1 1 1 1 Ets-domain Mastoparan_2 PF08251.11 RUS79706.1 - 0.0092 16.1 16.4 25 5.5 0.0 10.2 11 3 3 14 14 14 1 Mastoparan peptide RRM_1 PF00076.22 RUS79707.1 - 1.2e-18 66.6 0.0 2.8e-18 65.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS79707.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 RUS79707.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_7 PF16367.5 RUS79707.1 - 0.031 14.4 0.0 0.22 11.6 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif SET_assoc PF11767.8 RUS79707.1 - 0.04 13.6 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 RUS79707.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Phospholip_B PF04916.13 RUS79708.1 - 2.9e-57 194.5 0.1 3.7e-57 194.1 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B PX PF00787.24 RUS79709.1 - 1.6e-16 60.2 1.7 1.6e-15 57.1 0.2 2.3 2 1 0 2 2 2 1 PX domain FERM_M PF00373.18 RUS79709.1 - 0.0095 16.3 0.2 0.028 14.8 0.0 1.8 2 0 0 2 2 2 1 FERM central domain Ras_bdg_2 PF14847.6 RUS79709.1 - 0.015 15.6 0.7 0.13 12.6 0.1 2.5 2 1 0 2 2 2 0 Ras-binding domain of Byr2 RA PF00788.23 RUS79709.1 - 0.038 14.6 0.1 0.086 13.5 0.1 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain ABC_transp_aux PF09822.9 RUS79709.1 - 0.039 13.4 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system FERM_N PF09379.10 RUS79709.1 - 0.06 13.3 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 FERM N-terminal domain SNX17_FERM_C PF18116.1 RUS79710.1 - 3e-25 88.4 1.5 6.1e-25 87.4 0.4 1.9 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain Phage_tail_3 PF08813.11 RUS79710.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein, TTP REC114-like PF15165.6 RUS79711.1 - 4.7e-35 121.5 2.4 6.6e-33 114.5 2.4 2.0 1 1 0 1 1 1 1 Meiotic recombination protein REC114-like FMN_red PF03358.15 RUS79712.1 - 0.00034 20.4 0.0 0.11 12.3 0.0 2.3 1 1 1 2 2 2 2 NADPH-dependent FMN reductase NYN PF01936.18 RUS79712.1 - 0.15 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 NYN domain MFS_1 PF07690.16 RUS79713.1 - 2.5e-52 178.0 32.7 2.8e-51 174.5 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS79713.1 - 3.9e-11 42.5 1.7 3.9e-11 42.5 1.7 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 RUS79713.1 - 9.3e-06 24.4 16.3 0.0001 21.0 0.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein LpoB PF13036.6 RUS79714.1 - 0.019 14.9 0.0 54 3.7 0.0 3.3 1 1 3 4 4 4 0 Peptidoglycan-synthase activator LpoB Drf_FH1 PF06346.12 RUS79714.1 - 0.023 14.4 0.3 0.025 14.3 0.3 1.0 1 0 0 1 1 1 0 Formin Homology Region 1 DNA_ligase_C PF17879.1 RUS79714.1 - 0.16 12.0 0.7 9.9 6.3 0.0 2.5 1 1 2 3 3 3 0 DNA ligase C-terminal domain Ntox15 PF15604.6 RUS79714.1 - 1.7 8.7 6.4 57 3.8 2.5 3.4 1 1 1 2 2 2 0 Novel toxin 15 Ion_trans PF00520.31 RUS79715.1 - 1.1e-43 149.2 13.8 1.4e-43 148.9 13.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS79715.1 - 1e-29 102.7 0.0 9.5e-29 99.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS79715.1 - 1.1e-10 41.3 8.3 1.1e-10 41.3 8.3 2.2 2 1 0 2 2 2 1 Ion channel MARVEL PF01284.23 RUS79715.1 - 1.4 9.0 8.1 0.95 9.5 3.0 2.3 2 0 0 2 2 2 0 Membrane-associating domain COMM_domain PF07258.14 RUS79716.1 - 5.4e-17 61.7 0.7 1.1e-16 60.7 0.1 1.9 2 0 0 2 2 2 1 COMM domain Clr5 PF14420.6 RUS79716.1 - 0.11 12.7 0.2 0.29 11.4 0.2 1.7 1 0 0 1 1 1 0 Clr5 domain Cwf_Cwc_15 PF04889.12 RUS79717.1 - 1.2e-70 238.0 25.8 8.2e-70 235.3 25.8 1.8 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RICH PF05062.12 RUS79717.1 - 0.031 14.6 0.8 0.077 13.4 0.8 1.6 1 0 0 1 1 1 0 RICH domain GDPD PF03009.17 RUS79718.1 - 2.3e-10 40.6 0.0 3.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Sarcolipin PF05366.11 RUS79718.1 - 5.2 6.8 9.1 13 5.6 0.7 2.8 2 0 0 2 2 2 0 Sarcolipin APG6_N PF17675.1 RUS79719.1 - 0.00089 19.8 18.7 0.00089 19.8 18.7 20.6 1 1 16 18 18 18 8 Apg6 coiled-coil region Fib_alpha PF08702.10 RUS79719.1 - 0.002 18.3 7.5 0.002 18.3 7.5 15.5 4 3 11 16 16 16 3 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 RUS79719.1 - 0.0085 16.1 2.7 0.0085 16.1 2.7 29.9 5 5 26 32 32 32 5 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 RUS79719.1 - 0.091 12.8 384.0 0.018 15.0 14.9 18.6 2 2 14 17 17 17 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DPM3 PF08285.11 RUS79719.1 - 9.1 6.6 10.4 3.3 8.0 0.3 5.4 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) BROMI PF14961.6 RUS79720.1 - 0.11 9.9 3.3 0.14 9.6 3.3 1.0 1 0 0 1 1 1 0 Broad-minded protein Spc7 PF08317.11 RUS79720.1 - 1.5 7.6 17.8 2.7 6.8 17.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ACCA PF03255.14 RUS79720.1 - 4.4 7.2 10.0 0.64 9.9 4.9 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CLZ PF16526.5 RUS79720.1 - 6.3 7.2 21.1 0.062 13.7 4.8 3.3 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF572 PF04502.13 RUS79720.1 - 6.4 6.3 12.3 7 6.2 12.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) XRCC4 PF06632.12 RUS79720.1 - 8 5.2 14.9 12 4.6 14.5 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FA_hydroxylase PF04116.13 RUS79721.1 - 2.2e-25 89.5 19.7 2.2e-25 89.5 19.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DDE_Tnp_IS1595 PF12762.7 RUS79722.1 - 1.9e-17 63.7 0.0 4.8e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 ISXO2-like transposase domain Imm6 PF14434.6 RUS79722.1 - 0.098 12.6 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Immunity protein Imm6 DUF3963 PF13124.6 RUS79722.1 - 0.1 12.6 0.1 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) PT PF04886.12 RUS79723.1 - 7.5e-63 207.8 197.3 4.5e-13 48.5 37.5 6.3 1 1 1 2 2 2 1 PT repeat 5_nucleotid PF05761.14 RUS79724.1 - 1.3e-149 499.0 3.7 1.5e-149 498.8 3.7 1.0 1 0 0 1 1 1 1 5' nucleotidase family LisH_2 PF16045.5 RUS79724.1 - 0.077 12.0 0.3 0.16 11.0 0.3 1.5 1 0 0 1 1 1 0 LisH FSH1 PF03959.13 RUS79726.1 - 2.8e-55 187.2 0.1 3.3e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 RUS79726.1 - 5.6e-05 23.0 0.2 0.00018 21.4 0.1 1.7 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 RUS79726.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 RUS79726.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS79726.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1057 PF06342.12 RUS79726.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) zf-rbx1 PF12678.7 RUS79727.1 - 1.8e-21 76.1 17.3 3e-21 75.4 17.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RUS79727.1 - 2.2e-17 62.9 16.9 2.6e-17 62.6 16.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RUS79727.1 - 1.8e-06 28.2 22.0 1.6e-05 25.1 20.1 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS79727.1 - 0.0023 17.7 14.1 0.0023 17.7 14.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79727.1 - 0.02 14.8 11.9 0.02 14.8 11.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS79727.1 - 0.04 13.8 19.5 0.13 12.2 18.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS79727.1 - 0.53 10.3 20.1 2.9 7.9 18.6 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS79727.1 - 1.1 9.2 18.6 9 6.3 16.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L35Ae PF01247.18 RUS79728.1 - 2e-44 149.6 0.3 2.4e-44 149.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae IQ PF00612.27 RUS79729.1 - 3.9e-05 23.1 2.7 4.5e-05 22.9 0.6 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Spectrin PF00435.21 RUS79729.1 - 0.0012 19.3 9.5 0.0012 19.3 9.5 3.7 2 1 1 4 4 4 1 Spectrin repeat ArgoMid PF16487.5 RUS79729.1 - 0.37 11.1 3.8 6.2 7.2 0.5 2.8 1 1 1 2 2 2 0 Mid domain of argonaute DNA_primase_lrg PF04104.14 RUS79729.1 - 0.75 9.1 11.7 0.54 9.6 9.6 1.8 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Sulfotransfer_2 PF03567.14 RUS79731.1 - 1.4e-30 107.0 3.0 7.3e-28 98.1 0.8 2.2 2 0 0 2 2 2 2 Sulfotransferase family DUF5442 PF17514.2 RUS79731.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) THDPS_M PF14789.6 RUS79731.1 - 0.088 12.9 2.1 0.53 10.4 0.1 3.1 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle AAA_19 PF13245.6 RUS79732.1 - 0.51 10.7 7.9 34 4.8 7.9 2.4 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 RUS79735.1 - 5.7e-37 126.2 14.6 2.4e-16 60.1 0.5 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS79735.1 - 1.2e-26 92.7 4.4 8.5e-14 51.7 0.4 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS79735.1 - 6.3e-23 80.6 6.4 5.3e-10 39.4 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS79735.1 - 6.1e-19 66.1 5.9 0.0012 19.1 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RUS79735.1 - 1.3e-15 57.0 17.0 1.3e-05 25.4 0.2 6.2 7 0 0 7 7 7 3 Ankyrin repeat FAD_SOX PF18371.1 RUS79736.1 - 0.057 13.8 0.7 0.22 11.9 0.2 2.3 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MRP-S33 PF08293.11 RUS79736.1 - 0.062 13.5 3.1 0.27 11.5 3.1 2.1 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 zf-C2H2_4 PF13894.6 RUS79737.1 - 7.5e-09 35.7 85.6 0.022 15.6 0.1 12.9 12 1 0 12 12 12 7 C2H2-type zinc finger zf-Di19 PF05605.12 RUS79737.1 - 6.8e-07 29.5 67.5 0.00011 22.4 2.7 8.5 7 1 0 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RUS79737.1 - 0.00032 20.6 0.1 0.00032 20.6 0.1 6.9 8 0 0 8 8 8 3 C2H2-type zinc finger zf-met PF12874.7 RUS79737.1 - 0.006 16.9 33.8 0.063 13.7 0.1 8.7 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 RUS79737.1 - 0.03 14.8 0.1 0.03 14.8 0.1 11.0 12 1 0 12 12 12 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS79737.1 - 0.87 10.1 45.2 0.18 12.3 0.4 9.4 10 0 0 10 10 10 0 Zinc-finger double domain Cyclin_C_2 PF16899.5 RUS79738.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 RUS79738.1 - 0.039 13.7 3.9 0.045 13.5 1.4 2.5 2 1 0 2 2 2 0 Cyclin, N-terminal domain Pombe_5TM PF09437.10 RUS79738.1 - 0.12 12.0 8.9 0.08 12.6 5.4 2.0 1 1 1 2 2 2 0 Pombe specific 5TM protein AKAP28 PF14469.6 RUS79740.1 - 3.6e-53 178.5 4.0 5.9e-53 177.8 4.0 1.3 1 0 0 1 1 1 1 28 kDa A-kinase anchor Sulfotransfer_3 PF13469.6 RUS79741.1 - 6.2e-07 30.0 0.6 0.016 15.6 0.3 3.4 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS79741.1 - 0.022 14.2 0.0 0.2 11.1 0.0 2.3 1 1 0 1 1 1 0 Sulfotransferase domain Phage_Orf51 PF06194.11 RUS79742.1 - 0.73 9.9 10.6 5.5 7.1 0.3 3.4 1 1 3 4 4 4 0 Phage Conserved Open Reading Frame 51 SPX PF03105.19 RUS79743.1 - 0.44 10.4 11.0 0.87 9.4 9.8 1.8 1 1 1 2 2 2 0 SPX domain TPR_MLP1_2 PF07926.12 RUS79745.1 - 0.002 18.2 26.5 0.083 13.0 4.5 2.9 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RUS79745.1 - 0.0053 16.8 30.1 0.13 12.3 15.8 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 RUS79745.1 - 0.033 14.8 5.6 0.033 14.8 5.6 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5082 PF16888.5 RUS79745.1 - 0.083 13.2 19.5 3.7 7.9 0.9 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Phage_Gp19 PF09355.10 RUS79745.1 - 0.085 13.3 0.9 0.085 13.3 0.9 1.8 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Spc7 PF08317.11 RUS79745.1 - 0.11 11.3 28.3 0.087 11.7 17.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4472 PF14739.6 RUS79745.1 - 0.15 12.8 20.0 0.28 11.9 7.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 RUS79745.1 - 0.59 10.7 36.5 0.54 10.8 8.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region JIP_LZII PF16471.5 RUS79745.1 - 0.69 10.1 26.9 0.25 11.5 5.3 4.2 1 1 3 4 4 4 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 RUS79745.1 - 0.91 9.6 12.9 0.17 12.0 3.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 RUS79745.1 - 0.92 8.8 20.7 2.6 7.3 8.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 RUS79745.1 - 1.1 9.2 25.5 0.49 10.4 2.7 3.9 3 1 1 4 4 4 0 Prefoldin subunit ERM PF00769.19 RUS79745.1 - 1.5 8.5 28.9 0.81 9.5 8.0 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 RUS79745.1 - 1.6 8.5 20.7 12 5.7 12.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) LPP PF04728.13 RUS79745.1 - 2 8.9 10.9 0.59 10.6 0.4 3.7 3 1 1 4 4 4 0 Lipoprotein leucine-zipper SLATT_fungal PF18142.1 RUS79745.1 - 6 6.9 7.3 3.7 7.6 2.3 2.3 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain ZapB PF06005.12 RUS79745.1 - 6.5 7.3 32.6 20 5.7 2.3 4.1 1 1 3 4 4 4 0 Cell division protein ZapB HMMR_N PF15905.5 RUS79745.1 - 6.5 6.1 28.4 0.66 9.4 17.3 2.1 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HAUS-augmin3 PF14932.6 RUS79745.1 - 8.9 5.8 22.4 2 7.9 5.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 RUS79746.1 - 8.1e-05 22.1 9.1 8.1e-05 22.1 9.1 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 RUS79746.1 - 0.0092 15.8 16.2 0.0092 15.8 16.2 3.0 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH PV-1 PF06637.11 RUS79746.1 - 0.018 13.9 21.8 0.037 12.9 21.8 1.5 1 1 0 1 1 1 0 PV-1 protein (PLVAP) ERM PF00769.19 RUS79746.1 - 0.026 14.3 43.1 0.31 10.8 25.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 RUS79746.1 - 0.051 13.7 4.9 0.051 13.7 4.9 4.3 3 1 1 4 4 4 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 RUS79746.1 - 0.076 13.0 38.6 0.021 14.8 19.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 RUS79746.1 - 0.11 12.7 38.2 2.4 8.4 2.1 4.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 RUS79746.1 - 0.13 12.3 22.1 0.39 10.8 2.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 RUS79746.1 - 0.35 10.1 34.0 0.076 12.3 8.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 RUS79746.1 - 0.49 10.8 34.3 16 5.8 34.3 2.0 1 1 0 1 1 1 0 Fez1 SHE3 PF17078.5 RUS79746.1 - 0.55 9.9 25.1 3.3 7.4 15.1 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 RUS79746.1 - 0.72 10.4 46.2 0.046 14.3 13.7 3.4 1 1 3 4 4 4 0 Apg6 coiled-coil region YabA PF06156.13 RUS79746.1 - 1.3 9.7 25.0 6.1 7.5 7.9 3.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF5101 PF17031.5 RUS79746.1 - 1.5 9.0 13.4 4 7.6 4.5 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5101) CENP-H PF05837.12 RUS79746.1 - 1.6 9.2 30.8 0.12 12.8 11.0 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) CALCOCO1 PF07888.11 RUS79746.1 - 3.1 6.6 38.0 2.9 6.6 19.1 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 RUS79746.1 - 4.1 7.5 31.1 1.5 9.0 11.0 3.5 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase JIP_LZII PF16471.5 RUS79746.1 - 5 7.4 33.1 0.82 9.9 5.2 4.5 2 2 2 4 4 4 0 JNK-interacting protein leucine zipper II HIP1_clath_bdg PF16515.5 RUS79746.1 - 6 7.6 41.3 0.13 12.9 11.2 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 RUS79746.1 - 7.6 5.3 37.8 1.1 8.1 19.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Ovate PF04844.13 RUS79747.1 - 0.38 10.8 4.7 2.5e+02 1.7 0.0 5.4 6 2 1 7 7 7 0 Transcriptional repressor, ovate Myosin_tail_1 PF01576.19 RUS79748.1 - 8.5e-05 20.6 35.9 8.5e-05 20.6 35.9 4.6 2 2 2 4 4 4 2 Myosin tail ADIP PF11559.8 RUS79748.1 - 0.0011 19.1 8.0 0.0011 19.1 8.0 10.0 2 2 5 9 9 9 4 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 RUS79748.1 - 0.006 17.1 2.2 0.006 17.1 2.2 10.2 2 2 8 11 11 11 3 Apg6 coiled-coil region DUF3208 PF11482.8 RUS79748.1 - 0.34 11.2 2.2 6.1 7.2 0.3 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) Spc7 PF08317.11 RUS79748.1 - 5.1 5.9 141.8 0.063 12.1 14.2 7.3 2 2 5 7 7 7 0 Spc7 kinetochore protein PDEase_I PF00233.19 RUS79749.1 - 1.3e-54 185.5 7.1 2.8e-36 125.4 0.1 2.7 3 0 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Lipoprotein_6 PF01441.19 RUS79749.1 - 0.12 12.4 0.2 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Lipoprotein Pro_isomerase PF00160.21 RUS79753.1 - 5.8e-50 169.7 0.4 6.5e-50 169.5 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Collagen PF01391.18 RUS79755.1 - 2.1e-07 30.6 13.1 4.5e-07 29.5 13.1 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) VWC PF00093.18 RUS79755.1 - 5.6e-06 26.6 11.4 9.6e-06 25.8 11.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 RUS79755.1 - 0.0012 18.8 5.6 0.0012 18.8 5.6 1.7 1 1 0 1 1 1 1 TILa domain Collagen PF01391.18 RUS79756.1 - 4.9e-27 93.5 91.8 1.2e-10 41.0 26.5 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) COLFI PF01410.18 RUS79757.1 - 3.9e-58 196.5 0.3 5.5e-58 196.0 0.3 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Collagen PF01391.18 RUS79757.1 - 1.5e-43 146.4 168.2 7.7e-09 35.2 28.4 5.7 1 1 4 5 5 5 5 Collagen triple helix repeat (20 copies) DUF1272 PF06906.11 RUS79761.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.6 RUS79761.1 - 0.14 11.9 0.5 0.35 10.7 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RUS79761.1 - 0.32 10.5 1.3 0.42 10.1 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Collagen PF01391.18 RUS79762.1 - 1.6 8.5 90.2 1.8e+04 -5.6 13.1 4.2 2 2 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF4407 PF14362.6 RUS79763.1 - 9.8 5.4 9.3 2.7 7.3 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hexapep PF00132.24 RUS79764.1 - 6.9e-09 35.1 1.4 0.029 14.1 0.1 3.6 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF5387 PF17361.2 RUS79764.1 - 0.0054 16.4 0.8 0.11 12.1 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5387) Collagen PF01391.18 RUS79764.1 - 9.7 6.0 9.6 13 5.7 3.8 2.9 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Ion_trans PF00520.31 RUS79765.1 - 1.2e-05 24.7 7.7 1.6e-05 24.3 7.7 1.1 1 0 0 1 1 1 1 Ion transport protein YPEB PF14620.6 RUS79765.1 - 0.026 13.9 3.6 0.035 13.5 3.6 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF1943 PF09172.11 RUS79765.1 - 0.097 11.9 0.4 0.15 11.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2721 PF11026.8 RUS79765.1 - 0.17 11.8 4.5 1.1 9.1 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) CDC37_N PF03234.14 RUS79765.1 - 0.26 12.2 4.1 0.44 11.5 4.1 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Spc7 PF08317.11 RUS79765.1 - 0.53 9.1 5.5 0.74 8.6 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MCPsignal PF00015.21 RUS79765.1 - 0.54 10.1 4.7 2.7 7.8 1.0 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FadA PF09403.10 RUS79765.1 - 2 8.9 8.0 0.94 10.0 2.5 2.3 2 0 0 2 2 2 0 Adhesion protein FadA Pescadillo_N PF06732.11 RUS79768.1 - 5.3e-101 337.7 7.6 5.3e-101 337.7 7.6 1.9 2 1 1 3 3 3 1 Pescadillo N-terminus BRCT_2 PF16589.5 RUS79768.1 - 3.8e-11 43.3 0.0 1.1e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RUS79768.1 - 0.0018 18.6 0.1 0.017 15.5 0.1 2.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NYD-SP28_assoc PF14775.6 RUS79768.1 - 0.073 13.2 1.7 0.27 11.3 1.7 2.0 1 0 0 1 1 1 0 Sperm tail C-terminal domain LAP1C PF05609.12 RUS79768.1 - 6.6 5.7 22.2 11 4.9 22.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sulfotransfer_1 PF00685.27 RUS79769.1 - 2.9e-28 99.1 0.0 4.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS79769.1 - 6.9e-11 42.9 0.0 1.1e-10 42.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Dynein_heavy PF03028.15 RUS79769.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain EMG1 PF03587.14 RUS79770.1 - 2.2e-84 282.0 0.0 2.7e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MFS_1 PF07690.16 RUS79771.1 - 2e-12 46.7 20.0 2.8e-12 46.3 19.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS79771.1 - 5.4e-10 38.7 13.4 7.4e-10 38.3 13.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MRAP PF15183.6 RUS79771.1 - 0.3 11.0 3.3 0.38 10.7 1.8 1.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Arf PF00025.21 RUS79772.1 - 6.2e-34 117.0 0.0 8.2e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS79772.1 - 0.0008 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS79772.1 - 0.0017 18.0 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS79772.1 - 0.0027 17.1 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS79772.1 - 0.0055 16.2 0.1 1.3 8.5 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS79772.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RUS79772.1 - 0.1 11.7 0.8 2.1 7.4 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Annexin PF00191.20 RUS79772.1 - 0.12 12.5 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Annexin Neuroparsin PF07327.11 RUS79772.1 - 0.15 12.5 0.6 15 6.1 0.0 2.2 2 0 0 2 2 2 0 Neuroparsin ApeC PF16977.5 RUS79773.1 - 9.2e-39 133.5 2.9 1.3e-38 133.0 2.9 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin ApeC PF16977.5 RUS79774.1 - 4.2e-41 141.2 1.6 4.2e-41 141.2 1.6 1.7 2 0 0 2 2 2 1 C-terminal domain of apextrin SET PF00856.28 RUS79775.1 - 5.5e-20 72.4 0.2 3.1e-19 70.0 0.2 2.5 1 0 0 1 1 1 1 SET domain BAH PF01426.18 RUS79775.1 - 1.2e-17 63.9 0.0 2.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain AWS PF17907.1 RUS79775.1 - 2.5e-14 53.0 4.7 2.5e-14 53.0 4.7 3.3 4 0 0 4 4 4 1 AWS domain Bromodomain PF00439.25 RUS79775.1 - 2.5e-13 49.9 0.0 6.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RUS79775.1 - 2.4e-06 27.3 12.2 8.1e-06 25.6 12.2 2.0 1 0 0 1 1 1 1 PHD-finger AT_hook PF02178.19 RUS79775.1 - 0.78 9.8 16.8 6.7 6.9 4.7 3.6 2 0 0 2 2 2 0 AT hook motif PHD_2 PF13831.6 RUS79775.1 - 1.8 8.2 8.1 4.6 6.9 8.1 1.8 1 0 0 1 1 1 0 PHD-finger 7tm_2 PF00002.24 RUS79776.1 - 1.1e-34 119.8 12.6 1.3e-34 119.6 12.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 RUS79777.1 - 1.3e-14 54.1 1.0 1.5e-14 53.9 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Na_H_antiporter PF03553.14 RUS79777.1 - 0.031 13.5 0.3 0.035 13.3 0.3 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family mTERF PF02536.14 RUS79778.1 - 2.4e-08 33.3 1.7 2.8e-05 23.2 0.2 2.1 2 0 0 2 2 2 2 mTERF CHCH PF06747.13 RUS79779.1 - 5.2e-06 26.4 2.5 9e-06 25.7 1.6 1.8 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 RUS79779.1 - 6.4e-05 22.9 3.1 0.00013 21.9 1.2 2.0 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 RUS79779.1 - 0.013 15.7 1.2 0.023 14.9 1.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Dyp_perox PF04261.12 RUS79779.1 - 0.15 11.0 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Dyp-type peroxidase family HLH PF00010.26 RUS79780.1 - 1.4e-19 69.8 0.0 3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cir_N PF10197.9 RUS79781.1 - 1.3e-14 54.1 3.7 1.3e-14 54.1 3.7 1.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 RUS79782.1 - 0.00025 20.8 0.1 0.00048 19.9 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Cir_N PF10197.9 RUS79782.1 - 0.02 15.1 8.4 0.041 14.1 8.4 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR HTH_psq PF05225.16 RUS79783.1 - 1.1e-07 31.4 0.0 2.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 RUS79783.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DUF3365 PF11845.8 RUS79783.1 - 0.022 15.1 0.8 0.11 12.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) HTH_Tnp_1 PF01527.20 RUS79783.1 - 0.024 15.0 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 Transposase DRY_EERY PF09750.9 RUS79784.1 - 1.9e-39 135.0 0.0 1.9e-39 135.0 0.0 4.7 5 0 0 5 5 5 1 Alternative splicing regulator Herpes_UL6 PF01763.16 RUS79784.1 - 3.9 5.9 8.4 8.1 4.8 8.4 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Alpha-mann_mid PF09261.11 RUS79785.1 - 0.39 10.9 0.1 0.39 10.9 0.1 2.6 2 1 0 2 2 2 0 Alpha mannosidase middle domain zf-C2H2 PF00096.26 RUS79786.1 - 1.7e-10 40.7 13.4 2.8e-05 24.3 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS79786.1 - 5.6e-08 32.9 16.2 2.8e-07 30.6 3.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS79786.1 - 7.7e-06 26.3 12.4 0.021 15.6 4.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3268 PF11672.8 RUS79786.1 - 0.0047 17.2 0.5 0.0078 16.5 0.5 1.3 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_7 PF15269.6 RUS79786.1 - 0.0066 16.5 1.0 0.016 15.3 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 RUS79786.1 - 0.017 14.9 5.3 0.017 14.9 5.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain GAGA PF09237.11 RUS79786.1 - 0.073 12.9 0.8 0.16 11.8 0.8 1.6 1 0 0 1 1 1 0 GAGA factor zf-Di19 PF05605.12 RUS79786.1 - 0.099 12.9 5.0 0.2 12.0 5.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RUS79786.1 - 1.7 9.0 6.3 4.2 7.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS79787.1 - 2.7e-18 65.3 22.3 5.3e-07 29.7 2.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS79787.1 - 2.6e-15 56.1 17.9 1.2e-08 35.0 1.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS79787.1 - 1.7e-11 43.9 22.6 0.0006 20.4 2.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS79787.1 - 4.2e-06 26.4 5.4 4.2e-06 26.4 5.4 4.4 5 1 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS79787.1 - 6.4e-05 23.1 13.4 0.1 12.9 2.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 RUS79787.1 - 0.0078 16.1 8.0 0.045 13.6 2.0 2.4 1 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 RUS79787.1 - 0.023 14.5 1.6 0.45 10.4 0.3 2.3 1 1 1 2 2 2 0 GAGA factor zf-C2H2_7 PF15269.6 RUS79787.1 - 0.025 14.6 1.5 0.025 14.6 1.5 2.5 1 1 2 3 3 3 0 Zinc-finger zf-C2H2_6 PF13912.6 RUS79787.1 - 0.026 14.5 2.1 0.026 14.5 2.1 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 RUS79787.1 - 0.036 13.7 0.2 0.036 13.7 0.2 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 RUS79787.1 - 0.17 12.2 14.9 30 5.0 1.0 3.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RUS79787.1 - 0.2 12.1 0.1 0.2 12.1 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FYVE PF01363.21 RUS79787.1 - 0.32 11.2 14.7 2.6 8.3 0.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF3268 PF11672.8 RUS79787.1 - 0.44 10.9 9.6 0.11 12.9 4.9 1.9 1 1 1 2 2 2 0 zinc-finger-containing domain OrsD PF12013.8 RUS79787.1 - 0.49 10.9 7.4 4.9 7.6 2.2 2.7 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Sec23_Sec24 PF04810.15 RUS79787.1 - 0.67 10.0 6.2 1 9.5 0.1 3.0 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger C1_4 PF07975.12 RUS79787.1 - 3.4 8.0 10.1 0.19 12.0 1.2 2.4 1 1 2 3 3 3 0 TFIIH C1-like domain Fer4_21 PF14697.6 RUS79787.1 - 3.5 7.8 8.3 2.6 8.3 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-BED PF02892.15 RUS79787.1 - 4.4 7.4 18.6 19 5.4 0.2 3.4 2 1 0 2 2 2 0 BED zinc finger PyrI_C PF02748.15 RUS79787.1 - 4.9 7.1 11.7 4.3 7.3 0.7 3.1 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 RUS79787.1 - 5.4 6.7 7.5 4.6 6.9 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 RUS79788.1 - 0.01 16.2 1.4 1.5 9.4 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.10 RUS79788.1 - 0.037 13.8 1.2 0.076 12.7 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Trm112p PF03966.16 RUS79788.1 - 0.066 13.8 0.3 5.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Trm112p-like protein zf-met PF12874.7 RUS79788.1 - 0.15 12.5 1.2 0.79 10.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Utp14 PF04615.13 RUS79788.1 - 0.24 9.9 26.9 0.36 9.4 26.9 1.2 1 0 0 1 1 1 0 Utp14 protein zf-C2H2_4 PF13894.6 RUS79788.1 - 0.39 11.7 5.3 0.7 10.9 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 RUS79788.1 - 1.4 7.3 5.8 2 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-3CxxC_2 PF17180.4 RUS79788.1 - 2.7 8.8 6.7 0.5 11.2 1.8 2.3 2 0 0 2 2 2 0 Zinc-binding domain DUF3381 PF11861.8 RUS79788.1 - 3.6 7.4 13.2 13 5.5 13.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) TFIIF_alpha PF05793.12 RUS79788.1 - 8.1 4.9 34.4 14 4.2 34.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 RUS79792.1 - 0.00016 21.2 12.5 0.00019 21.0 12.5 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 RUS79792.1 - 0.003 17.2 17.2 0.004 16.8 17.2 1.1 1 0 0 1 1 1 1 PPP4R2 Secretin_N_2 PF07655.13 RUS79792.1 - 0.095 13.2 10.7 0.25 11.9 9.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DNA_pol_phi PF04931.13 RUS79792.1 - 0.1 10.7 25.9 0.038 12.1 22.6 1.7 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.12 RUS79792.1 - 0.11 10.7 16.8 0.15 10.2 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS79792.1 - 0.24 9.7 10.9 0.33 9.2 10.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Orf78 PF06024.12 RUS79792.1 - 0.91 9.9 12.8 7.2 7.0 0.3 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Osteopontin PF00865.18 RUS79792.1 - 9.8 5.6 30.6 0.16 11.4 23.1 1.7 2 0 0 2 2 2 0 Osteopontin CopK PF11525.8 RUS79794.1 - 0.0032 17.0 2.1 12 5.7 0.3 4.2 2 2 4 6 6 6 3 Copper resistance protein K RBM1CTR PF08081.11 RUS79794.1 - 0.13 12.3 35.8 6.6 6.9 1.9 5.4 1 1 3 5 5 5 0 RBM1CTR (NUC064) family DUF1720 PF08226.11 RUS79794.1 - 0.43 11.0 3.4 18 5.8 3.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Acetate_kinase PF00871.17 RUS79794.1 - 5.5 5.6 8.4 45 2.6 0.1 3.7 2 1 0 2 2 2 0 Acetokinase family LRR_8 PF13855.6 RUS79795.1 - 1.1e-10 41.1 15.7 2.4e-10 40.0 2.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RUS79795.1 - 3.5e-08 33.6 14.7 3.4e-05 24.1 0.2 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS79795.1 - 0.0059 16.1 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RUS79795.1 - 0.0094 16.4 10.2 0.6 10.9 0.4 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS79795.1 - 0.068 13.3 5.9 1.8 8.8 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat WD40 PF00400.32 RUS79796.1 - 3.1e-23 81.6 18.3 2.8e-06 27.9 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS79796.1 - 2.7e-10 40.4 0.0 1 9.7 0.0 5.9 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.16 RUS79796.1 - 1.1e-07 32.0 0.6 1.9e-07 31.3 0.6 1.4 1 0 0 1 1 1 1 SOCS box Ge1_WD40 PF16529.5 RUS79796.1 - 2.4e-05 23.5 0.1 1.2 8.1 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein 3-HAO PF06052.12 RUS79797.1 - 5.9e-64 214.3 0.1 2.5e-63 212.2 0.1 1.9 2 1 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 RUS79797.1 - 3.1e-09 36.4 0.1 1.8e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 RUS79797.1 - 0.00094 19.1 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 RUS79797.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Cupin 2OG-FeII_Oxy_5 PF13759.6 RUS79797.1 - 0.18 12.2 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Peptidase_S24 PF00717.23 RUS79798.1 - 5.8e-06 26.2 0.0 0.29 11.1 0.0 4.0 1 1 0 1 1 1 1 Peptidase S24-like DUF5018 PF16410.5 RUS79798.1 - 0.0008 18.2 0.3 0.12 11.0 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5018) WD40_like PF17005.5 RUS79798.1 - 0.01 15.2 0.5 0.039 13.3 0.5 1.8 1 1 0 1 1 1 0 WD40-like domain BTB PF00651.31 RUS79800.1 - 2.7e-23 82.3 0.0 6.2e-15 55.4 0.0 3.3 2 2 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 RUS79800.1 - 8.9e-09 35.4 0.4 2.7e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch FANCL_C PF11793.8 RUS79801.1 - 5.6e-08 32.8 6.0 8.3 6.7 0.1 7.2 1 1 7 8 8 8 1 FANCL C-terminal domain Mntp PF02659.15 RUS79801.1 - 5.7e-07 29.4 0.1 0.77 9.5 0.0 3.9 1 1 3 4 4 4 4 Putative manganese efflux pump DBD_HTH PF18430.1 RUS79801.1 - 0.00079 19.1 0.7 4.3e+02 0.8 0.0 7.5 10 0 0 10 10 10 0 Putative DNA-binding domain Ntox27 PF15531.6 RUS79801.1 - 0.0011 18.9 1.4 12 5.8 0.1 3.6 1 1 2 3 3 3 0 Bacterial toxin 27 MOZART1 PF12554.8 RUS79801.1 - 0.0011 18.6 0.2 93 2.9 0.0 5.0 3 1 2 5 5 5 0 Mitotic-spindle organizing gamma-tubulin ring associated Attacin_C PF03769.15 RUS79801.1 - 0.0012 19.1 2.8 8.3 6.7 0.1 4.4 1 1 3 4 4 4 2 Attacin, C-terminal region Ycf9 PF01737.17 RUS79801.1 - 0.014 15.2 19.3 13 5.7 0.1 6.5 1 1 3 7 7 7 0 YCF9 Flu_B_M2 PF04772.12 RUS79801.1 - 0.016 15.5 4.1 35 4.7 0.1 3.9 1 1 3 4 4 4 0 Influenza B matrix protein 2 (BM2) DUF725 PF05267.12 RUS79801.1 - 0.023 14.7 0.9 1 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF725) DUF630 PF04783.12 RUS79801.1 - 0.03 14.5 0.0 1.3e+02 2.9 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF630) Mad3_BUB1_I PF08311.12 RUS79801.1 - 0.058 13.4 0.2 27 4.8 0.0 2.9 1 1 3 4 4 4 0 Mad3/BUB1 homology region 1 DUF294 PF03445.13 RUS79801.1 - 0.11 12.3 0.4 37 4.1 0.0 3.1 2 1 2 4 4 4 0 Putative nucleotidyltransferase DUF294 Antiterm PF03589.13 RUS79801.1 - 0.18 12.2 1.5 1e+02 3.3 0.1 3.5 1 1 2 3 3 3 0 Antitermination protein Opiods_neuropep PF01160.18 RUS79801.1 - 0.23 11.6 2.8 1.9e+02 2.2 0.2 4.6 3 1 1 4 4 4 0 Vertebrate endogenous opioids neuropeptide BetaGal_dom4_5 PF13364.6 RUS79801.1 - 0.45 11.1 9.9 11 6.7 1.0 3.3 1 1 1 2 2 2 0 Beta-galactosidase jelly roll domain UPA PF17217.3 RUS79801.1 - 0.7 9.8 10.7 61 3.5 0.1 4.7 1 1 4 7 7 7 0 UPA domain ETAA1 PF15350.6 RUS79802.1 - 3.4e-06 25.7 29.5 0.00062 18.2 0.0 4.2 4 0 0 4 4 4 3 Ewing's tumour-associated antigen 1 homologue 7tm_1 PF00001.21 RUS79803.1 - 8.5e-15 54.8 0.0 2e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS79803.1 - 0.0019 17.6 0.5 0.0019 17.6 0.5 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ntox50 PF15542.6 RUS79804.1 - 3.3 8.6 23.2 1.6e+02 3.2 0.7 6.7 1 1 4 5 5 5 0 Bacterial toxin 50 MBD PF01429.19 RUS79805.1 - 4.1e-11 42.4 0.1 1.1e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 Methyl-CpG binding domain PHD PF00628.29 RUS79806.1 - 0.00024 20.9 7.7 0.00054 19.8 7.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RUS79806.1 - 0.0085 16.3 4.0 0.0085 16.3 4.0 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain HTH_psq PF05225.16 RUS79806.1 - 0.0097 15.6 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain F-box-like PF12937.7 RUS79806.1 - 0.023 14.6 0.2 0.06 13.2 0.2 1.7 1 0 0 1 1 1 0 F-box-like zf-RING_2 PF13639.6 RUS79806.1 - 0.2 12.0 8.0 0.5 10.7 8.0 1.7 1 0 0 1 1 1 0 Ring finger domain EGF PF00008.27 RUS79808.1 - 4.7e-18 65.1 91.5 4.1e-06 27.0 7.2 7.9 8 0 0 8 8 8 5 EGF-like domain hEGF PF12661.7 RUS79808.1 - 3.9e-13 49.5 72.9 8.9e-05 23.0 6.3 8.6 8 0 0 8 8 8 7 Human growth factor-like EGF FXa_inhibition PF14670.6 RUS79808.1 - 0.0083 16.4 68.6 4.4 7.7 2.2 7.7 4 2 3 7 7 7 5 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 RUS79808.1 - 0.01 16.2 8.9 0.01 16.2 8.9 7.8 7 0 0 7 7 7 0 EGF-like domain Laminin_EGF PF00053.24 RUS79808.1 - 0.2 11.8 87.0 21 5.3 4.0 7.6 2 2 5 7 7 7 0 Laminin EGF domain EGF_3 PF12947.7 RUS79808.1 - 0.42 10.8 76.4 0.51 10.6 5.4 7.8 6 1 1 7 7 7 0 EGF domain EGF_CA PF07645.15 RUS79808.1 - 0.76 10.0 88.6 0.023 14.9 9.8 7.8 6 1 1 7 7 7 0 Calcium-binding EGF domain ENTH PF01417.20 RUS79810.1 - 2.1e-49 166.7 1.0 2.5e-49 166.5 0.3 1.5 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 RUS79810.1 - 4.3e-06 25.9 0.1 5.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 RUS79810.1 - 0.012 15.5 0.3 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 VHS domain UIM PF02809.20 RUS79810.1 - 0.17 11.9 7.9 2.1 8.5 2.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif GDPD PF03009.17 RUS79811.1 - 3e-23 82.9 0.0 2.9e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RDD PF06271.12 RUS79811.1 - 0.078 13.2 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 2 0 RDD family Hrs_helical PF12210.8 RUS79812.1 - 6.2e-40 135.6 4.1 6.2e-40 135.6 4.1 2.8 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 RUS79812.1 - 6.4e-18 64.7 12.5 1.3e-17 63.7 12.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger VHS PF00790.19 RUS79812.1 - 1.2e-05 25.2 6.4 1.2e-05 25.2 0.0 3.4 4 0 0 4 4 4 1 VHS domain UIM PF02809.20 RUS79812.1 - 0.0039 17.0 3.7 0.012 15.5 3.7 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DZR PF12773.7 RUS79812.1 - 0.13 12.3 11.4 1.1 9.4 3.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF938 PF06080.12 RUS79814.1 - 5.7e-72 241.8 0.0 7.4e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 RUS79814.1 - 9.1e-08 32.7 0.0 1.5e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS79814.1 - 0.00012 22.7 0.0 0.00021 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RUS79814.1 - 0.005 16.3 0.0 0.0087 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 RUS79814.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 RUS79814.1 - 0.053 14.3 0.0 0.088 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Macro PF01661.21 RUS79815.1 - 4e-28 97.8 1.6 5e-28 97.5 0.1 1.9 2 0 0 2 2 2 1 Macro domain Histone PF00125.24 RUS79815.1 - 4.6e-15 56.1 0.6 7.8e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 RUS79815.1 - 2.8e-14 52.5 0.4 7.3e-14 51.2 0.4 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 RUS79815.1 - 0.0004 20.6 0.0 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.20 RUS79815.1 - 0.041 14.0 0.2 0.12 12.5 0.2 1.8 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Folliculin_C PF16692.5 RUS79816.1 - 4.2e-72 242.5 1.3 6.2e-71 238.7 1.3 2.1 1 1 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 RUS79816.1 - 2.1e-51 174.5 0.0 3.9e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pyr_redox_2 PF07992.14 RUS79817.1 - 4.1e-10 39.4 0.0 4.5e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS79817.1 - 0.0026 17.9 0.0 0.0077 16.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 RUS79817.1 - 0.012 16.1 0.0 0.51 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 RUS79817.1 - 0.02 15.1 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 RUS79817.1 - 0.056 13.5 0.1 19 5.3 0.0 3.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 RUS79817.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 RUS79817.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pterin_4a PF01329.19 RUS79818.1 - 1.7e-32 111.5 0.1 2.2e-32 111.1 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Prefoldin_2 PF01920.20 RUS79820.1 - 2e-18 66.3 0.0 2.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Nup88 PF10168.9 RUS79820.1 - 0.033 12.0 0.0 0.038 11.8 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore component Plasmodium_Vir PF05795.11 RUS79821.1 - 0.21 11.0 0.0 0.21 11.0 0.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2615 PF11027.8 RUS79822.1 - 0.0015 18.6 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2615) Shisa PF13908.6 RUS79822.1 - 0.0027 18.0 15.9 0.019 15.2 6.1 2.8 2 1 1 3 3 3 2 Wnt and FGF inhibitory regulator Syndecan PF01034.20 RUS79822.1 - 0.16 11.9 1.0 0.44 10.5 1.0 1.7 1 0 0 1 1 1 0 Syndecan domain Pkinase_Tyr PF07714.17 RUS79823.1 - 6e-35 120.8 0.0 8.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS79823.1 - 7.7e-32 110.7 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 RUS79823.1 - 2e-12 46.3 0.1 3.9e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 RUS79823.1 - 0.0037 18.3 8.3 0.0037 18.3 8.3 2.6 3 0 0 3 3 3 1 Activin types I and II receptor domain APH PF01636.23 RUS79823.1 - 0.019 14.9 0.1 0.061 13.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 RUS79823.1 - 0.044 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF4990 PF16380.5 RUS79823.1 - 0.088 12.9 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF4448 PF14610.6 RUS79823.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glycophorin_A PF01102.18 RUS79823.1 - 0.18 12.1 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A UPAR_LY6 PF00021.21 RUS79823.1 - 1.5 9.6 6.5 6 7.6 6.5 2.1 1 1 0 1 1 1 0 u-PAR/Ly-6 domain LdpA_C PF12617.8 RUS79824.1 - 0.014 15.0 0.4 0.028 14.0 0.4 1.5 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal ShK PF01549.24 RUS79825.1 - 1.2e-06 28.9 15.1 0.00012 22.5 3.6 3.9 3 1 2 5 5 5 2 ShK domain-like zf-CCCH PF00642.24 RUS79825.1 - 0.021 14.7 2.8 3.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ArsD PF06953.11 RUS79826.1 - 9.4e-07 29.2 7.6 1.8e+02 2.5 0.0 10.4 2 1 11 13 13 13 0 Arsenical resistance operon trans-acting repressor ArsD DUF1161 PF06649.12 RUS79826.1 - 2.3e-06 27.7 10.1 24 5.2 0.1 9.1 1 1 9 10 10 10 5 Protein of unknown function (DUF1161) RhoGEF PF00621.20 RUS79828.1 - 2.3e-40 138.8 6.8 3.1e-40 138.3 6.8 1.2 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 RUS79828.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Aminotran_5 PF00266.19 RUS79828.1 - 0.063 12.2 0.1 0.093 11.7 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V CARD PF00619.21 RUS79828.1 - 0.1 12.6 0.4 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Caspase recruitment domain CBP_CCPA PF17040.5 RUS79829.1 - 0.022 15.4 2.0 0.06 13.9 2.0 1.8 1 0 0 1 1 1 0 Cellulose-complementing protein A Poty_PP PF08440.10 RUS79829.1 - 0.072 12.2 0.1 0.092 11.8 0.1 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein PIG-X PF08320.12 RUS79829.1 - 0.38 10.6 1.7 12 5.7 0.4 2.1 2 0 0 2 2 2 0 PIG-X / PBN1 Med19 PF10278.9 RUS79829.1 - 5.5 6.9 7.2 1.6 8.6 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Biliv-reduc_cat PF09166.10 RUS79830.1 - 0.2 12.0 0.0 0.27 11.6 0.0 1.1 1 0 0 1 1 1 0 Biliverdin reductase, catalytic Activin_recp PF01064.23 RUS79830.1 - 1.5 10.0 21.2 2.4 9.3 20.9 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain DUF1397 PF07165.11 RUS79831.1 - 0.14 11.6 4.8 0.23 10.8 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1397) DNA_primase_lrg PF04104.14 RUS79832.1 - 1.2e-10 41.2 0.4 1.5e-10 41.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DBR1 PF05011.13 RUS79833.1 - 2.5e-32 112.2 0.0 3.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 RUS79834.1 - 2.2e-13 51.2 0.2 3.3e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YL1_C PF08265.11 RUS79834.1 - 0.11 12.3 1.0 29 4.5 0.0 3.5 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain DUF3622 PF12286.8 RUS79834.1 - 0.11 12.9 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) DUF3522 PF12036.8 RUS79836.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) PIRT PF15099.6 RUS79837.1 - 0.00059 19.4 0.1 0.0015 18.1 0.1 1.7 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM100 PF16311.5 RUS79837.1 - 0.0023 17.5 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 100 DUF3040 PF11239.8 RUS79837.1 - 0.078 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TCR_zetazeta PF11628.8 RUS79837.1 - 0.082 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain TMEM171 PF15471.6 RUS79837.1 - 0.12 11.3 1.3 0.24 10.4 0.0 2.0 2 1 0 2 2 2 0 Transmembrane protein family 171 TMEM174 PF15029.6 RUS79837.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.4 2 1 0 2 2 2 0 Transmembrane protein 174 TMEM238 PF15125.6 RUS79837.1 - 0.5 10.6 1.9 1.1 9.5 1.6 1.7 1 1 0 1 1 1 0 TMEM238 protein family MFS_1_like PF12832.7 RUS79839.1 - 7.1e-58 196.3 8.5 9.5e-58 195.9 8.5 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RUS79839.1 - 1.6e-08 33.9 45.9 0.00024 20.1 15.7 3.4 3 1 1 4 4 4 3 Major Facilitator Superfamily YcxB PF14317.6 RUS79839.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 YcxB-like protein MFS_3 PF05977.13 RUS79839.1 - 2.8 6.2 8.6 0.55 8.6 2.9 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Pyridoxal_deC PF00282.19 RUS79840.1 - 3.7e-10 39.1 0.0 1.7e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SesA PF17107.5 RUS79840.1 - 0.038 14.2 0.2 0.22 11.7 0.0 2.4 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF948 PF06103.11 RUS79840.1 - 0.046 14.0 0.6 4.4 7.6 0.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC142 PF14923.6 RUS79840.1 - 0.28 9.9 2.7 0.41 9.3 0.3 2.4 3 0 0 3 3 3 0 Coiled-coil protein 142 WD40 PF00400.32 RUS79841.1 - 2.3e-27 94.7 19.9 5.7e-06 27.0 1.3 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-C3HC4_4 PF15227.6 RUS79841.1 - 3e-07 30.5 2.7 1.2e-06 28.5 2.7 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS79841.1 - 5.1e-07 29.6 4.7 5.1e-07 29.6 4.7 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-TRAF PF02176.18 RUS79841.1 - 1.6e-06 28.7 5.1 1.6e-06 28.7 5.1 2.6 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 RUS79841.1 - 1.1e-05 25.2 3.9 1.1e-05 25.2 3.9 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS79841.1 - 1.1e-05 25.1 6.8 1.6e-05 24.7 4.6 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS79841.1 - 1.6e-05 24.7 4.2 7.3e-05 22.5 4.2 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 RUS79841.1 - 7.2e-05 22.8 7.1 0.0024 17.8 3.5 2.5 1 1 1 2 2 2 1 Seven in absentia protein family Nup160 PF11715.8 RUS79841.1 - 0.00011 21.0 3.0 0.16 10.5 0.1 3.9 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Prok-RING_4 PF14447.6 RUS79841.1 - 0.00012 21.9 5.0 0.00012 21.9 5.0 2.4 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS79841.1 - 0.00017 21.5 4.3 0.00017 21.5 4.3 2.5 3 0 0 3 3 1 1 zinc-RING finger domain PKcGMP_CC PF16808.5 RUS79841.1 - 0.00054 19.8 0.0 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 RUS79841.1 - 0.00061 19.8 6.7 0.015 15.3 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 RUS79841.1 - 0.0055 16.5 1.6 0.018 14.9 1.6 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 RUS79841.1 - 0.0079 16.6 4.1 0.0079 16.6 4.1 3.6 2 1 2 4 4 2 1 TRAF-like zinc-finger DUF641 PF04859.12 RUS79841.1 - 0.0081 16.5 0.4 0.0081 16.5 0.4 2.0 2 0 0 2 2 1 1 Plant protein of unknown function (DUF641) zf-RING_2 PF13639.6 RUS79841.1 - 0.027 14.8 4.6 0.027 14.8 4.6 3.2 4 0 0 4 4 1 0 Ring finger domain DUF1272 PF06906.11 RUS79841.1 - 0.028 14.5 2.1 0.028 14.5 2.1 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) U-box PF04564.15 RUS79841.1 - 0.044 14.0 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 U-box domain zf-met PF12874.7 RUS79841.1 - 0.046 14.1 0.2 0.3 11.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SlyX PF04102.12 RUS79841.1 - 0.048 14.3 6.0 4.2 8.1 0.2 2.5 1 1 1 2 2 2 0 SlyX Spc7 PF08317.11 RUS79841.1 - 0.06 12.2 5.6 0.088 11.7 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.6 RUS79841.1 - 0.11 12.8 1.6 0.21 11.9 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) zf-HC2 PF13490.6 RUS79841.1 - 0.11 12.7 0.4 2 8.8 0.1 2.7 2 0 0 2 2 2 0 Putative zinc-finger ATG16 PF08614.11 RUS79841.1 - 0.11 12.7 3.9 0.19 11.9 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 RUS79841.1 - 0.11 12.0 0.7 0.17 11.4 0.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2H2_jaz PF12171.8 RUS79841.1 - 0.15 12.4 5.0 0.34 11.3 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Bacillus_HBL PF05791.11 RUS79841.1 - 0.19 11.5 2.0 0.32 10.8 2.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GvpL_GvpF PF06386.11 RUS79841.1 - 0.21 11.5 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF NPV_P10 PF05531.12 RUS79841.1 - 0.31 11.5 2.6 0.89 10.1 0.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 RUS79841.1 - 0.33 11.3 2.8 0.68 10.2 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) HMMR_N PF15905.5 RUS79841.1 - 0.37 10.2 6.8 0.57 9.6 6.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc42p PF11544.8 RUS79841.1 - 0.48 10.5 3.1 1.2 9.2 3.1 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p Fib_alpha PF08702.10 RUS79841.1 - 0.48 10.6 7.6 0.069 13.3 0.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 RUS79841.1 - 0.8 10.2 5.0 1.7 9.2 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 RUS79841.1 - 1.2 9.4 8.6 0.44 10.8 4.9 2.1 1 1 1 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 RUS79841.1 - 2.9 8.3 7.0 3.8 8.0 4.6 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) zf-Nse PF11789.8 RUS79841.1 - 4.7 7.1 9.2 0.15 11.9 0.9 2.8 3 1 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit Snapin_Pallidin PF14712.6 RUS79841.1 - 8.9 6.8 8.5 14 6.2 7.7 1.8 1 1 0 1 1 1 0 Snapin/Pallidin YWFCY PF14293.6 RUS79842.1 - 0.024 15.0 1.3 8.5 6.8 0.0 3.7 2 1 2 4 4 4 0 YWFCY protein DUF1751 PF08551.10 RUS79844.1 - 1.5e-24 86.4 4.7 1.5e-24 86.4 4.7 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 RUS79844.1 - 6.9e-06 26.1 11.8 6.9e-06 26.1 11.8 1.9 2 0 0 2 2 2 1 Rhomboid family DEAD PF00270.29 RUS79846.1 - 1.1e-32 113.2 0.2 2.8e-32 111.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS79846.1 - 2.2e-23 82.7 0.3 2e-22 79.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS79846.1 - 3.2e-05 24.0 0.0 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 RUS79846.1 - 0.00057 19.3 0.1 0.0017 17.8 0.1 1.8 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 RUS79846.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS79846.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RUS79846.1 - 0.048 13.9 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Lig_chan-Glu_bd PF10613.9 RUS79847.1 - 3.2e-28 98.2 0.0 1.4e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS79847.1 - 2.5e-27 95.8 0.0 6.4e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 RUS79847.1 - 2.1e-26 92.5 0.1 5.2e-26 91.3 0.1 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel OAD_gamma PF04277.13 RUS79847.1 - 0.75 10.4 9.4 0.59 10.8 3.1 3.1 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Big_5 PF13205.6 RUS79848.1 - 0.14 12.9 34.1 4.8 7.9 1.1 8.3 2 1 6 8 8 8 0 Bacterial Ig-like domain Big_9 PF17963.1 RUS79848.1 - 1.7 9.4 20.7 4.6 8.0 0.1 6.4 1 1 5 7 7 7 0 Bacterial Ig domain LolA PF03548.15 RUS79848.1 - 5.7 6.6 11.6 2.1 8.0 0.3 4.4 2 2 2 5 5 5 0 Outer membrane lipoprotein carrier protein LolA Collagen_mid PF15984.5 RUS79849.1 - 1.2e-09 38.2 0.2 3.2e-06 27.1 0.0 2.5 1 1 1 2 2 2 2 Bacterial collagen, middle region DUF1664 PF07889.12 RUS79849.1 - 0.00014 21.9 0.0 0.27 11.3 0.0 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) UPF0184 PF03670.13 RUS79849.1 - 0.0031 17.9 0.1 6.9 7.1 0.0 3.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0184) SNARE PF05739.19 RUS79849.1 - 0.038 14.0 0.0 48 4.0 0.0 3.8 2 1 2 5 5 5 0 SNARE domain DUF5107 PF17128.4 RUS79849.1 - 0.31 10.2 2.2 3.6 6.7 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5107) RtxA PF07634.11 RUS79849.1 - 0.73 10.5 16.5 66 4.4 0.1 6.3 5 1 1 6 6 6 0 RtxA repeat D_CNTX PF17492.2 RUS79849.1 - 3 8.1 6.3 2.4 8.4 3.2 2.3 1 1 1 2 2 2 0 Delta Ctenitoxins cEGF PF12662.7 RUS79851.1 - 7.6 6.6 6.3 5.1 7.1 2.4 2.7 2 1 0 2 2 2 0 Complement Clr-like EGF-like HLH PF00010.26 RUS79853.1 - 1e-07 31.8 0.8 1.9e-07 30.9 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sec23_trunk PF04811.15 RUS79855.1 - 8.5e-69 231.8 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RUS79855.1 - 4.4e-22 77.9 1.9 7.8e-22 77.1 1.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RUS79855.1 - 1.4e-19 70.6 0.0 2.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RUS79855.1 - 2.9e-14 52.8 4.4 7e-14 51.6 4.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RUS79855.1 - 0.025 14.5 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat Mucin-like PF16058.5 RUS79856.1 - 0.0068 16.5 0.2 0.0082 16.2 0.2 1.1 1 0 0 1 1 1 1 Mucin-like MRP-S24 PF14955.6 RUS79857.1 - 3.1e-49 166.4 0.1 4e-49 166.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 Arf PF00025.21 RUS79859.1 - 6.5e-64 214.6 0.0 7.4e-64 214.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RUS79859.1 - 8.6e-12 44.9 0.0 2.1e-09 37.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RUS79859.1 - 4.3e-10 39.3 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RUS79859.1 - 3.1e-08 33.9 0.0 8.8e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS79859.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 RUS79859.1 - 1.6e-06 27.9 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS79859.1 - 3.9e-05 23.1 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 RUS79859.1 - 6e-05 22.7 0.0 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 RUS79859.1 - 0.034 13.7 0.1 1.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 RUS79859.1 - 0.23 11.2 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BTB PF00651.31 RUS79861.1 - 1.4e-23 83.2 0.2 4.8e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS79861.1 - 3.3e-09 36.8 0.9 2e-08 34.3 0.2 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS79861.1 - 6.7e-05 23.0 0.0 0.01 16.1 0.0 3.0 1 1 1 2 2 2 1 Kelch motif DUF3342 PF11822.8 RUS79861.1 - 0.00036 20.7 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.25 RUS79861.1 - 0.0036 16.9 0.2 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 Kelch motif DUF4722 PF15849.5 RUS79861.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) DUF5327 PF17261.2 RUS79861.1 - 0.13 13.0 0.5 0.37 11.6 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Astacin PF01400.24 RUS79862.1 - 2.4e-54 183.9 0.1 3.3e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 RUS79862.1 - 1.6e-14 54.1 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Peptidase_M10 PF00413.24 RUS79862.1 - 0.35 10.7 2.1 2.4 8.0 0.9 2.5 2 1 0 2 2 2 0 Matrixin Acetyltransf_1 PF00583.25 RUS79863.1 - 5.3e-12 46.0 0.0 7.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS79863.1 - 2.5e-05 24.6 0.0 3.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS79863.1 - 0.00023 21.1 0.0 0.00039 20.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS79863.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RUS79863.1 - 0.16 12.0 0.0 0.92 9.6 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RUS79863.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RNase_T PF00929.24 RUS79864.1 - 1.5e-08 35.3 0.0 7.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Exonuclease 7TM_GPCR_Srx PF10328.9 RUS79867.1 - 7 6.2 25.4 28 4.2 23.9 2.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ins134_P3_kin PF05770.11 RUS79869.1 - 2.4e-51 174.1 0.3 4.2e-51 173.3 0.3 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 RUS79869.1 - 3.9e-12 46.4 0.0 7.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain RAM PF15320.6 RUS79870.1 - 0.00011 22.8 29.3 0.031 14.9 29.3 2.2 1 1 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein PDZ PF00595.24 RUS79871.1 - 2e-19 69.7 0.1 2.7e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS79871.1 - 1.6e-08 34.7 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS79871.1 - 4.3e-06 26.5 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RUS79871.1 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain SAM_4 PF18017.1 RUS79872.1 - 3.3e-27 94.3 0.0 5.8e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS79872.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS79872.1 - 0.00085 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2624 PF11116.8 RUS79872.1 - 0.062 14.2 0.0 0.18 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) AMPK1_CBM PF16561.5 RUS79873.1 - 7e-29 99.9 1.6 4.7e-28 97.2 1.6 2.0 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RUS79873.1 - 9.5e-25 86.7 3.1 2e-24 85.6 3.1 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 RUS79873.1 - 0.0073 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 RUS79873.1 - 0.15 12.6 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Redoxin PF08534.10 RUS79874.1 - 2.2e-35 121.5 0.1 2.6e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RUS79874.1 - 2e-11 43.9 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Plus-3 PF03126.18 RUS79876.1 - 3.1e-34 117.8 0.1 1e-33 116.1 0.1 1.9 1 0 0 1 1 1 1 Plus-3 domain EGF PF00008.27 RUS79877.1 - 4.2e-14 52.5 20.5 3.6e-07 30.4 9.7 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS79877.1 - 2.1e-08 34.5 22.0 4.8e-05 23.8 2.8 3.4 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_CA PF07645.15 RUS79877.1 - 1.3e-05 25.2 22.4 0.018 15.3 8.5 2.7 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 RUS79877.1 - 0.0031 17.7 8.1 0.0031 17.7 8.1 3.1 3 0 0 3 3 3 1 EGF domain cEGF PF12662.7 RUS79877.1 - 0.0043 17.0 8.9 0.075 13.0 3.0 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS79877.1 - 0.045 14.0 7.0 0.045 14.0 7.0 3.3 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS79878.1 - 1e-05 25.7 6.4 3.2e-05 24.1 6.4 1.9 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 RUS79878.1 - 0.00022 21.8 8.6 0.00022 21.8 8.6 2.7 4 0 0 4 4 4 1 Human growth factor-like EGF EGF_CA PF07645.15 RUS79878.1 - 0.052 13.8 8.5 0.052 13.8 8.5 2.0 2 0 0 2 2 2 0 Calcium-binding EGF domain Globin PF00042.22 RUS79879.1 - 1.2e-13 51.5 0.1 1.5e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Globin DUF2205 PF10224.9 RUS79879.1 - 0.027 14.4 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Short coiled-coil protein DUF4096 PF13340.6 RUS79880.1 - 0.00069 19.8 69.9 12 6.2 1.0 12.3 1 1 24 25 25 25 23 Putative transposase of IS4/5 family (DUF4096) DUF1989 PF09347.10 RUS79880.1 - 0.2 11.3 45.7 15 5.2 0.2 10.8 1 1 17 18 18 18 0 Domain of unknown function (DUF1989) Keratin_B2_2 PF13885.6 RUS79882.1 - 1.9e-14 53.3 67.6 1.1e-05 25.3 26.0 3.1 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein PMG PF05287.12 RUS79882.1 - 0.0025 17.9 35.1 0.046 13.8 19.7 2.4 1 1 0 1 1 1 1 PMG protein Keratin_B2 PF01500.17 RUS79882.1 - 0.018 15.1 64.5 0.48 10.4 32.1 2.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein AAA PF00004.29 RUS79883.1 - 4.5e-40 137.1 0.1 4.5e-39 133.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RUS79883.1 - 3e-06 27.1 0.0 9.3e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS79883.1 - 5.2e-06 26.8 1.4 0.025 14.8 0.1 4.1 2 1 0 3 3 3 1 AAA domain TniB PF05621.11 RUS79883.1 - 0.00011 21.7 0.2 3.9 6.8 0.0 3.7 3 1 0 4 4 4 2 Bacterial TniB protein AAA_5 PF07728.14 RUS79883.1 - 0.00011 22.2 0.1 0.0009 19.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RUS79883.1 - 0.0003 20.1 0.0 0.00061 19.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Vps4_C PF09336.10 RUS79883.1 - 0.00099 19.1 0.0 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RUS79883.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RUS79883.1 - 0.0015 18.3 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein MIT PF04212.18 RUS79883.1 - 0.0021 18.1 0.4 0.0056 16.7 0.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 RUS79883.1 - 0.0065 16.9 0.4 0.065 13.6 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RUS79883.1 - 0.0098 15.3 0.3 0.04 13.3 0.3 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RUS79883.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RUS79883.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RHD_DNA_bind PF00554.22 RUS79884.1 - 3.4e-06 27.1 0.5 7.5e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain bZIP_2 PF07716.15 RUS79885.1 - 9e-06 25.7 22.8 1.7e-05 24.8 22.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS79885.1 - 0.00041 20.4 22.3 0.00072 19.6 22.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Nop53 PF07767.11 RUS79885.1 - 0.024 14.1 13.5 0.033 13.6 13.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) bZIP_Maf PF03131.17 RUS79885.1 - 0.057 13.9 19.3 0.1 13.1 19.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CDC45 PF02724.14 RUS79885.1 - 0.27 9.5 10.6 0.38 9.0 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 RUS79885.1 - 0.78 9.1 3.5 1.2 8.5 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GBP_C PF02841.14 RUS79885.1 - 1.1 8.6 12.6 1.6 8.1 12.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PspB PF06667.12 RUS79885.1 - 1.7 8.8 5.9 3 7.9 5.9 1.4 1 0 0 1 1 1 0 Phage shock protein B FYDLN_acid PF09538.10 RUS79886.1 - 0.0002 22.0 3.9 0.0002 22.0 3.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 RUS79886.1 - 0.00072 19.5 34.1 0.016 15.0 6.5 2.1 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 RXT2_N PF08595.11 RUS79886.1 - 0.0015 18.5 5.7 0.0015 18.5 5.7 2.2 2 0 0 2 2 2 1 RXT2-like, N-terminal GPCR_chapero_1 PF11904.8 RUS79886.1 - 0.0025 17.3 13.9 0.0036 16.8 13.9 1.2 1 0 0 1 1 1 1 GPCR-chaperone SpoIIP PF07454.11 RUS79886.1 - 0.0068 15.9 0.7 0.0068 15.9 0.7 2.1 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) Mpp10 PF04006.12 RUS79886.1 - 0.0074 14.8 13.3 0.0074 14.8 13.3 2.0 2 0 0 2 2 1 1 Mpp10 protein FAM176 PF14851.6 RUS79886.1 - 0.016 14.9 8.3 0.016 14.9 8.3 2.4 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 RUS79886.1 - 0.016 15.0 1.3 0.016 15.0 1.3 2.1 2 0 0 2 2 2 0 Connexin Eapp_C PF10238.9 RUS79886.1 - 0.016 15.2 0.2 0.016 15.2 0.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein CobT PF06213.12 RUS79886.1 - 0.018 14.4 12.4 0.018 14.4 12.4 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 RUS79886.1 - 0.037 15.0 0.2 0.037 15.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 RUS79886.1 - 0.042 14.2 1.2 0.042 14.2 1.2 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4471 PF14740.6 RUS79886.1 - 0.054 12.7 0.4 0.054 12.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF2956 PF11169.8 RUS79886.1 - 0.058 13.6 0.3 0.058 13.6 0.3 3.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2956) DUF719 PF05334.13 RUS79886.1 - 0.12 12.5 21.0 1.2 9.3 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DAG_kinase_N PF14513.6 RUS79886.1 - 0.13 12.4 15.3 0.21 11.8 9.7 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus CPSF100_C PF13299.6 RUS79886.1 - 0.24 11.6 28.2 0.12 12.5 3.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 RUS79886.1 - 0.25 11.8 24.9 0.14 12.6 4.2 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ORC_WH_C PF18137.1 RUS79886.1 - 0.35 10.9 32.7 0.33 11.0 8.7 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF5308 PF17233.2 RUS79886.1 - 0.37 11.0 11.5 2.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) CTU2 PF10288.9 RUS79886.1 - 0.39 11.0 17.2 0.41 10.9 1.1 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Vfa1 PF08432.10 RUS79886.1 - 0.44 10.9 48.6 0.66 10.3 30.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 RUS79886.1 - 0.91 8.5 45.2 0.63 9.0 21.2 2.1 2 0 0 2 2 2 0 Paf1 AAA_11 PF13086.6 RUS79886.1 - 1.3 8.7 24.3 2.3 7.9 14.1 2.0 2 0 0 2 2 2 0 AAA domain LicD PF04991.13 RUS79886.1 - 1.6 8.8 19.2 0.2 11.8 14.6 1.7 2 0 0 2 2 2 0 LicD family DUF913 PF06025.12 RUS79886.1 - 2 7.3 19.1 0.17 10.8 0.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.14 RUS79886.1 - 2.2 8.0 25.3 0.47 10.2 1.3 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_23 PF13476.6 RUS79886.1 - 2.2 8.7 39.8 0.68 10.4 19.6 2.1 2 0 0 2 2 2 0 AAA domain Nop53 PF07767.11 RUS79886.1 - 2.2 7.6 61.0 2.4 7.5 20.2 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) RPN2_C PF18004.1 RUS79886.1 - 3.4 7.6 61.3 0.058 13.3 12.0 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 RUS79886.1 - 3.7 5.7 40.8 0.35 9.1 11.9 2.0 2 0 0 2 2 2 0 CDC45-like protein CENP-N PF05238.13 RUS79886.1 - 4 6.7 28.0 4.2 6.6 18.9 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like GAGA_bind PF06217.12 RUS79886.1 - 4.4 7.5 30.1 2 8.7 24.0 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family PRC2_HTH_1 PF18118.1 RUS79886.1 - 4.6 8.1 33.8 9 7.2 5.9 2.3 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Pox_Ag35 PF03286.14 RUS79886.1 - 5 6.9 49.2 3.6 7.3 22.7 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TCP PF03634.13 RUS79886.1 - 5.7 7.5 30.4 0.75 10.3 18.2 2.2 2 0 0 2 2 2 0 TCP family transcription factor Nop14 PF04147.12 RUS79886.1 - 5.9 5.0 41.2 0.13 10.4 17.0 2.1 2 0 0 2 2 2 0 Nop14-like family PcfK PF14058.6 RUS79886.1 - 5.9 7.2 43.4 1.3 9.3 28.1 2.3 2 0 0 2 2 2 0 PcfK-like protein DUF3807 PF12720.7 RUS79886.1 - 6.8 6.9 45.2 0.61 10.3 23.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF5427 PF10310.9 RUS79886.1 - 7.1 5.5 35.3 0.25 10.3 6.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) CDC27 PF09507.10 RUS79886.1 - 8.5 5.7 49.1 4 6.7 12.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SID-1_RNA_chan PF13965.6 RUS79886.1 - 9.3 4.5 9.1 5.9 5.2 0.4 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PIRT PF15099.6 RUS79887.1 - 0.066 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3188 PF11384.8 RUS79887.1 - 9.3 6.0 7.3 0.75 9.6 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) MFS_1 PF07690.16 RUS79888.1 - 5e-07 29.0 7.5 6.1e-07 28.7 7.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS79890.1 - 1.8e-09 37.0 33.2 5.5e-07 28.8 20.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 RUS79890.1 - 0.27 9.6 12.0 0.53 8.6 12.0 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector DSL PF01414.19 RUS79891.1 - 1.4e-26 92.5 62.5 1e-14 54.5 5.1 12.4 9 4 2 11 11 11 4 Delta serrate ligand EGF PF00008.27 RUS79891.1 - 3.9e-15 55.8 194.2 6.2e-07 29.6 6.3 14.8 14 2 0 14 14 14 8 EGF-like domain hEGF PF12661.7 RUS79891.1 - 1.7e-05 25.3 5.8 1.7e-05 25.3 5.8 14.9 14 2 0 14 14 14 5 Human growth factor-like EGF EGF_2 PF07974.13 RUS79891.1 - 0.0015 18.8 6.4 0.0015 18.8 6.4 16.9 17 1 1 18 18 18 8 EGF-like domain Tmemb_9 PF05434.11 RUS79891.1 - 0.067 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 TMEM9 DJ-1_PfpI PF01965.24 RUS79892.1 - 2e-11 44.0 0.0 5e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 RUS79892.1 - 0.0081 15.9 0.1 0.19 11.4 0.1 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like Cnd1 PF12717.7 RUS79893.1 - 0.0046 17.0 0.7 0.0046 17.0 0.7 4.9 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 SIX1_SD PF16878.5 RUS79893.1 - 2.4 8.7 4.8 2.3 8.7 0.1 3.3 4 0 0 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain TGF_beta PF00019.20 RUS79895.1 - 5.8e-31 107.6 0.2 1.7e-30 106.1 0.2 1.9 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS79895.1 - 8.3e-12 45.4 0.5 3.4e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 TGF-beta propeptide Abhydrolase_3 PF07859.13 RUS79896.1 - 5e-15 55.9 0.0 2.5e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 RUS79896.1 - 1.4e-13 50.6 0.0 5e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS79896.1 - 0.00049 19.6 0.0 0.83 9.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS79896.1 - 0.0017 19.0 0.1 0.0055 17.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS79896.1 - 0.037 13.3 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RUS79896.1 - 0.037 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1749 PF08538.10 RUS79896.1 - 0.041 13.0 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 RUS79896.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 RUS79896.1 - 0.051 13.4 0.0 7.4 6.3 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 RUS79896.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Period_C PF12114.8 RUS79896.1 - 4.7 6.8 13.1 0.097 12.3 6.4 1.5 2 0 0 2 2 2 0 Period protein 2/3C-terminal region PT PF04886.12 RUS79897.1 - 0.025 14.1 18.5 2.1 8.0 4.4 4.3 2 2 1 3 3 3 0 PT repeat SDA1 PF05285.12 RUS79898.1 - 0.22 10.9 29.8 0.3 10.5 29.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS79898.1 - 2.4 6.2 34.2 3.4 5.8 34.2 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS79898.1 - 8.8 4.3 49.9 16 3.4 49.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RUS79898.1 - 9.9 4.8 8.9 1.7 7.3 5.5 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BRICHOS PF04089.14 RUS79900.1 - 0.043 14.1 0.6 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 BRICHOS domain Delta_lysin PF05372.11 RUS79900.1 - 0.065 12.5 0.2 0.19 11.1 0.2 1.7 1 0 0 1 1 1 0 Delta lysin family HhH-GPD PF00730.25 RUS79902.1 - 1.1e-19 70.8 0.0 2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RUS79902.1 - 1.9e-06 27.5 0.0 5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Spc7 PF08317.11 RUS79903.1 - 0.025 13.5 1.4 0.063 12.1 1.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Cas_TM1802 PF09484.10 RUS79903.1 - 0.035 12.9 0.3 0.066 11.9 0.3 1.4 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Prominin PF05478.11 RUS79903.1 - 0.12 10.4 1.2 0.17 9.8 0.0 1.8 2 0 0 2 2 2 0 Prominin ATG16 PF08614.11 RUS79903.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.8 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) CCDC-167 PF15188.6 RUS79903.1 - 0.39 11.1 2.2 1 9.8 0.4 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 EzrA PF06160.12 RUS79903.1 - 0.88 7.7 8.5 1.2 7.2 0.7 2.9 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 RUS79903.1 - 0.97 8.7 7.1 0.71 9.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 RUS79903.1 - 1.1 9.3 4.9 0.49 10.4 1.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF848 PF05852.11 RUS79903.1 - 1.8 8.6 6.7 8 6.6 0.5 3.4 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) CAF20 PF17052.5 RUS79903.1 - 2.1 8.5 6.7 0.23 11.6 0.5 2.6 4 0 0 4 4 4 0 Cap associated factor RasGAP_C PF03836.15 RUS79903.1 - 2.6 8.2 9.6 2.5 8.2 0.3 3.5 3 1 1 4 4 4 0 RasGAP C-terminus Homeodomain PF00046.29 RUS79905.1 - 0.00058 19.7 1.5 0.0013 18.5 1.0 1.9 2 0 0 2 2 2 1 Homeodomain PET117 PF15786.5 RUS79905.1 - 0.68 10.2 3.8 1.5 9.2 3.8 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF4605 PF15378.6 RUS79906.1 - 1.5e-16 59.9 6.3 2e-16 59.6 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) SRA1 PF07304.11 RUS79907.1 - 0.00042 20.1 0.0 0.9 9.3 0.0 2.7 2 0 0 2 2 2 2 Steroid receptor RNA activator (SRA1) KA1 PF02149.19 RUS79907.1 - 0.0066 16.2 2.4 3.4 7.5 0.1 3.0 3 0 0 3 3 3 2 Kinase associated domain 1 YfaZ PF07437.11 RUS79907.1 - 0.015 14.9 0.0 7.8 6.1 0.0 2.4 2 0 0 2 2 2 0 YfaZ precursor Mrx7 PF10906.8 RUS79907.1 - 0.017 15.3 0.1 9.6 6.5 0.0 2.6 2 0 0 2 2 2 0 MIOREX complex component 7 Fapy_DNA_glyco PF01149.24 RUS79907.1 - 0.057 14.0 0.0 5.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain RasGEF_N PF00618.20 RUS79907.1 - 0.12 12.6 0.0 27 5.1 0.0 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif SP_C-Propep PF08999.10 RUS79907.1 - 0.14 11.9 0.1 27 4.6 0.0 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF3403 PF11883.8 RUS79907.1 - 0.18 11.9 0.0 40 4.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) CRISPR_assoc PF08798.11 RUS79907.1 - 0.55 10.3 2.9 35 4.4 0.0 3.6 4 1 1 5 5 5 0 CRISPR associated protein FAR1 PF03101.15 RUS79907.1 - 2.2 9.0 7.1 7.4 7.3 0.0 3.2 3 0 0 3 3 3 0 FAR1 DNA-binding domain fn3 PF00041.21 RUS79908.1 - 4.4e-23 81.4 1.4 8.8e-07 29.2 0.2 5.0 3 3 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS79908.1 - 1.4e-05 25.6 9.1 0.17 12.5 0.1 5.0 4 1 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain HEAT_2 PF13646.6 RUS79908.1 - 4.2e-05 23.8 0.3 0.65 10.4 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats fn3_2 PF16893.5 RUS79908.1 - 0.0012 18.9 0.0 1.6 8.9 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain HEAT_EZ PF13513.6 RUS79908.1 - 0.009 16.5 0.3 33 5.1 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat DUF2369 PF10179.9 RUS79908.1 - 0.01 16.2 0.0 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Proteasom_PSMB PF10508.9 RUS79908.1 - 0.017 13.6 0.2 0.61 8.5 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit MAP65_ASE1 PF03999.12 RUS79908.1 - 6.7 5.3 12.0 11 4.5 12.0 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TFR_dimer PF04253.15 RUS79909.1 - 4e-15 56.0 0.0 5.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain C2 PF00168.30 RUS79910.1 - 1.3e-23 83.2 0.2 1.9e-10 40.9 0.0 2.4 2 1 0 2 2 2 2 C2 domain TP2 PF01254.18 RUS79910.1 - 5 7.7 11.6 9.6 6.8 11.6 1.5 1 1 0 1 1 1 0 Nuclear transition protein 2 MFS_1 PF07690.16 RUS79911.1 - 5.8e-18 64.9 7.5 7.1e-18 64.6 7.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 RUS79911.1 - 1.1e-07 31.0 1.8 2e-07 30.2 1.8 1.4 1 1 0 1 1 1 1 LacY proton/sugar symporter ATG22 PF11700.8 RUS79911.1 - 0.00067 18.4 0.9 0.00086 18.0 0.9 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like OATP PF03137.20 RUS79911.1 - 0.28 9.4 5.2 0.67 8.2 4.9 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 RUS79911.1 - 2.7 7.2 11.8 1.2 8.4 0.7 2.3 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB CBM_14 PF01607.24 RUS79912.1 - 7.1e-09 35.7 2.6 7.1e-09 35.7 2.6 1.9 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain zf-H2C2_2 PF13465.6 RUS79913.1 - 1.7e-22 78.8 46.4 8.3e-07 29.2 1.3 6.6 6 1 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS79913.1 - 4.6e-19 67.7 57.4 3.2e-06 27.3 2.7 7.4 7 1 1 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS79913.1 - 5e-15 54.9 48.3 0.00067 20.3 2.0 6.8 6 1 1 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 RUS79913.1 - 2.6e-07 30.8 39.7 0.0031 17.9 0.9 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS79913.1 - 0.00037 20.4 36.0 0.46 10.5 0.8 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 RUS79913.1 - 0.00057 20.1 31.2 0.0048 17.1 6.3 3.6 2 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RUS79913.1 - 0.0045 17.3 4.0 0.072 13.4 0.2 6.3 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RUS79913.1 - 0.012 15.5 18.4 0.055 13.4 0.1 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RUS79913.1 - 0.032 14.3 3.7 0.032 14.3 3.7 4.3 3 2 1 4 4 4 0 Zinc ribbon domain BolA PF01722.18 RUS79913.1 - 0.081 13.2 0.8 4.9 7.5 0.2 3.3 2 1 2 4 4 4 0 BolA-like protein DUF2256 PF10013.9 RUS79913.1 - 0.17 12.0 9.1 14 5.9 0.1 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 RUS79913.1 - 3.5 7.5 31.8 0.65 9.8 0.2 5.9 6 0 0 6 6 6 0 zinc-finger C2H2-type Sugar_tr PF00083.24 RUS79915.1 - 2.1e-37 129.1 2.5 2.2e-37 129.0 2.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS79915.1 - 1.5e-08 34.0 2.7 1.6e-08 33.9 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS79915.1 - 0.00069 18.6 1.3 0.004 16.1 0.6 2.0 1 1 1 2 2 2 2 MFS_1 like family DUF3792 PF12670.7 RUS79915.1 - 0.61 10.3 9.3 1.5 9.0 9.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DUF5592 PF17332.2 RUS79915.1 - 1.1 9.8 5.3 19 5.9 1.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5592) PIRT PF15099.6 RUS79916.1 - 0.02 14.5 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF973 PF06157.11 RUS79916.1 - 0.057 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) TMEM174 PF15029.6 RUS79916.1 - 0.18 11.5 3.2 0.13 11.9 0.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 174 Ras PF00071.22 RUS79917.1 - 1.1e-32 112.8 0.0 1.6e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS79917.1 - 2.3e-23 82.7 0.0 3.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS79917.1 - 1.1e-07 31.5 0.4 3.1e-07 30.0 0.4 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS79917.1 - 0.00032 20.2 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS79917.1 - 0.00068 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS79917.1 - 0.00071 19.5 0.1 1.3 8.9 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 RUS79917.1 - 0.00076 19.0 0.0 0.0019 17.7 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS79917.1 - 0.0023 17.5 0.2 0.086 12.4 0.1 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RUS79917.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RUS79917.1 - 0.0086 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS79917.1 - 0.028 13.9 0.1 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 RUS79917.1 - 0.035 13.8 0.1 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 RUS79917.1 - 0.064 13.6 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF4867 PF16161.5 RUS79917.1 - 0.079 12.4 0.0 0.63 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4867) ATP_bind_1 PF03029.17 RUS79917.1 - 0.1 12.3 0.2 0.76 9.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 RUS79917.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE p450 PF00067.22 RUS79918.1 - 1.2e-105 353.9 0.0 1.4e-105 353.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reprolysin PF01421.19 RUS79919.1 - 3.8e-11 43.3 0.3 1e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS79919.1 - 6.5e-09 36.2 0.1 1.1e-08 35.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS79919.1 - 3.5e-08 34.0 0.1 6.7e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS79919.1 - 1.5e-05 25.0 0.1 2.5e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS79919.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS79919.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Acyl_transf_2 PF02273.15 RUS79919.1 - 0.15 11.3 0.1 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Acyl transferase zf-H2C2_2 PF13465.6 RUS79920.1 - 1e-42 142.7 96.9 1.6e-08 34.6 1.0 13.6 13 1 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 RUS79920.1 - 3.4e-35 118.5 106.4 0.00013 22.2 2.9 13.8 13 1 0 13 13 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS79920.1 - 2.5e-33 111.9 95.2 0.0048 17.6 0.1 13.7 13 0 0 13 13 13 12 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS79920.1 - 5.6e-08 32.6 94.1 0.00022 21.1 0.1 14.1 13 1 0 13 13 13 6 C2H2-type zinc finger zf-met PF12874.7 RUS79920.1 - 8e-06 26.1 78.2 0.055 13.9 0.2 12.5 13 0 0 13 13 11 6 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS79920.1 - 0.00011 22.5 64.8 0.35 11.2 0.5 9.0 5 2 4 9 9 9 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RUS79920.1 - 0.00064 19.4 55.7 0.032 14.0 0.3 9.5 10 0 0 10 10 10 4 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS79920.1 - 0.0025 18.1 1.9 0.048 14.0 0.3 13.6 14 0 0 14 14 14 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RUS79920.1 - 0.023 14.6 59.6 0.12 12.3 1.8 12.1 12 0 0 12 12 12 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 RUS79920.1 - 0.039 14.6 53.2 1.1 10.0 3.2 9.2 1 1 7 9 9 9 0 Zinc finger C2H2-type, 3 repeats Csm1_N PF18504.1 RUS79920.1 - 0.99 9.8 5.4 1.6 9.2 0.2 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain BolA PF01722.18 RUS79920.1 - 1.6 9.1 16.4 4.1 7.7 0.0 6.8 4 2 3 7 7 7 0 BolA-like protein XPA_N PF01286.18 RUS79920.1 - 1.9 8.6 0.0 1.9 8.6 0.0 11.9 13 0 0 13 13 13 0 XPA protein N-terminal GAGA PF09237.11 RUS79920.1 - 3.6 7.5 0.0 3.6 7.5 0.0 6.1 5 2 3 8 8 8 0 GAGA factor Nuc_sug_transp PF04142.15 RUS79921.1 - 2.9e-34 118.7 28.2 3.6e-34 118.4 28.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RUS79921.1 - 0.013 15.7 32.9 0.39 10.9 8.2 2.6 2 1 0 2 2 2 0 EamA-like transporter family BT1 PF03092.16 RUS79922.1 - 0.051 11.8 0.3 0.083 11.1 0.3 1.3 1 0 0 1 1 1 0 BT1 family DinI PF06183.13 RUS79924.1 - 0.13 12.6 1.0 0.37 11.2 0.1 2.1 1 1 1 2 2 2 0 DinI-like family CWC25 PF12542.8 RUS79924.1 - 1.7 9.6 9.7 0.79 10.6 5.9 2.2 2 1 1 3 3 3 0 Pre-mRNA splicing factor DUF382 PF04037.13 RUS79925.1 - 2.4e-59 199.0 2.4 2.4e-59 199.0 2.4 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 RUS79925.1 - 3.3e-20 71.7 3.3 1.8e-19 69.3 3.3 2.4 1 0 0 1 1 1 1 PSP tRNA-synt_2b PF00587.25 RUS79926.1 - 4.3e-27 95.2 0.0 7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PIG-F PF06699.11 RUS79927.1 - 2.9e-40 138.4 7.4 3.4e-40 138.1 7.4 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF3995 PF13160.6 RUS79927.1 - 0.023 15.0 0.6 0.023 15.0 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) DUF2678 PF10856.8 RUS79927.1 - 0.99 9.4 4.6 2.5 8.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) MFS_1 PF07690.16 RUS79929.1 - 3e-13 49.4 29.3 1.6e-07 30.6 7.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.12 RUS79929.1 - 0.041 13.6 0.8 0.062 13.0 0.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 RUS79929.1 - 0.15 12.4 0.0 7.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_desaturase PF00487.24 RUS79929.1 - 0.61 9.9 0.0 0.61 9.9 0.0 3.1 3 1 0 3 3 3 0 Fatty acid desaturase YdjO PF14169.6 RUS79931.1 - 0.0056 16.4 1.8 0.0059 16.3 0.2 1.9 2 0 0 2 2 2 1 Cold-inducible protein YdjO Homeodomain PF00046.29 RUS79932.1 - 1.4e-22 79.3 9.3 3.7e-22 77.9 9.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS79932.1 - 0.015 15.2 0.8 0.049 13.5 0.8 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 RUS79932.1 - 0.091 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Period_C PF12114.8 RUS79933.1 - 0.0018 17.9 1.3 0.0029 17.2 1.3 1.3 1 0 0 1 1 1 1 Period protein 2/3C-terminal region Baculo_11_kDa PF06143.11 RUS79933.1 - 1.7 8.3 9.5 0.052 13.1 2.4 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family RhoGAP PF00620.27 RUS79935.1 - 9.3e-41 139.2 0.2 6.9e-40 136.3 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.28 RUS79935.1 - 4.3e-12 45.5 0.0 8.6e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS79935.1 - 1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS79935.1 - 3.8e-09 36.1 0.0 7.9e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4164 PF13747.6 RUS79935.1 - 0.0024 18.1 6.9 0.36 11.2 0.8 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) APG6_N PF17675.1 RUS79935.1 - 0.074 13.6 10.6 0.19 12.3 6.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 RUS79935.1 - 0.18 12.2 0.2 0.18 12.2 0.2 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 RUS79935.1 - 0.57 10.3 12.0 4.5 7.4 6.8 2.5 2 0 0 2 2 2 0 Tropomyosin like Allexi_40kDa PF05549.11 RUS79935.1 - 0.59 9.6 4.2 14 5.1 1.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein HAUS6_N PF14661.6 RUS79935.1 - 0.96 9.0 11.6 0.75 9.3 8.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF745 PF05335.13 RUS79935.1 - 2.4 7.9 9.7 4.4 7.0 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 RUS79935.1 - 2.4 7.4 14.2 5.8 6.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 RUS79935.1 - 6.8 6.5 11.9 8.8 6.1 5.6 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 YlqD PF11068.8 RUS79935.1 - 6.9 7.1 13.3 3.8 7.9 8.9 2.2 2 0 0 2 2 2 0 YlqD protein PHD_3 PF13922.6 RUS79936.1 - 0.0065 16.8 1.6 0.021 15.2 1.6 1.8 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx Pepsin-I3 PF06394.13 RUS79938.1 - 0.78 10.0 11.2 2 8.7 2.1 2.5 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Lamprin PF06403.11 RUS79938.1 - 2 8.4 11.3 6.6 6.7 4.2 2.3 1 1 1 2 2 2 0 Lamprin Pentapeptide_2 PF01469.18 RUS79939.1 - 0.033 14.1 0.0 0.033 14.1 0.0 6.9 8 0 0 8 8 8 0 Pentapeptide repeats (8 copies) Umbravirus_LDM PF04817.12 RUS79939.1 - 4.9 6.4 8.1 23 4.2 0.2 2.9 1 1 3 5 5 5 0 Umbravirus long distance movement (LDM) family DUF5543 PF17697.1 RUS79940.1 - 0.69 10.2 16.7 74 3.7 0.0 7.6 1 1 8 9 9 9 0 Family of unknown function (DUF5543) Retinin_C PF04527.12 RUS79940.1 - 0.99 9.7 6.5 1.6e+02 2.6 0.5 5.5 1 1 2 3 3 3 0 Drosophila Retinin like protein Pentapeptide_2 PF01469.18 RUS79941.1 - 0.00025 20.9 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) NADH_dh_m_C1 PF15088.6 RUS79941.1 - 0.00041 19.9 2.1 0.55 9.9 0.1 2.8 1 1 2 3 3 3 2 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Hol_Tox PF16935.5 RUS79941.1 - 0.27 11.3 0.4 77 3.4 0.0 2.9 3 0 0 3 3 3 0 Putative Holin-like Toxin (Hol-Tox) Antimicrobial_5 PF08026.11 RUS79941.1 - 6.7 6.9 33.3 15 5.8 0.9 5.5 5 0 0 5 5 5 0 Bee antimicrobial peptide Herpes_BLLF1 PF05109.13 RUS79943.1 - 2.6e-07 29.1 18.2 0.00057 18.0 8.0 2.1 1 1 1 2 2 2 2 Herpes virus major outer envelope glycoprotein (BLLF1) Phage_GP20 PF06810.11 RUS79943.1 - 5.9e-07 29.4 3.4 0.13 12.1 0.2 4.2 1 1 2 3 3 3 2 Phage minor structural protein GP20 NUC130_3NT PF08158.12 RUS79943.1 - 0.00045 20.5 11.5 54 4.2 0.0 8.4 8 2 2 10 10 10 0 NUC130/3NT domain DUF2203 PF09969.9 RUS79943.1 - 0.00055 20.7 0.2 2.6 8.8 0.0 3.6 1 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2203) ApoC-I PF04691.12 RUS79943.1 - 0.0014 18.5 1.0 9.8 6.2 0.0 5.0 3 2 4 7 7 7 1 Apolipoprotein C-I (ApoC-1) Laminin_II PF06009.12 RUS79943.1 - 0.01 15.9 0.2 2.6 8.1 0.0 2.7 1 1 1 2 2 2 0 Laminin Domain II CRM1_C PF08767.11 RUS79943.1 - 0.051 12.7 2.2 12 5.0 0.1 3.1 2 1 1 3 3 3 0 CRM1 C terminal DUF948 PF06103.11 RUS79943.1 - 0.16 12.2 4.0 5 7.5 0.2 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.11 RUS79943.1 - 0.22 12.2 1.5 26 5.6 0.2 3.0 1 1 2 3 3 3 0 Cytochrome b562 MscS_porin PF12795.7 RUS79943.1 - 0.93 9.0 3.0 11 5.5 0.7 2.8 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF778 PF05608.12 RUS79943.1 - 1.6 9.0 7.9 14 5.9 0.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF778) QH-AmDH_gamma PF08992.11 RUS79943.1 - 2.6 8.1 14.5 34 4.5 0.3 5.7 1 1 4 5 5 5 0 Quinohemoprotein amine dehydrogenase, gamma subunit WD40_3 PF15911.5 RUS79943.1 - 2.6 8.1 13.4 1.3e+02 2.6 0.1 6.8 3 3 5 9 9 9 0 WD domain, G-beta repeat DUF4744 PF15918.5 RUS79943.1 - 3.3 8.6 10.4 29 5.6 2.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4744) PDZ_assoc PF10600.9 RUS79944.1 - 0.034 15.0 14.5 63 4.5 0.1 6.3 1 1 3 4 4 4 0 PDZ-associated domain of NMDA receptors AIM24 PF01987.17 RUS79944.1 - 0.06 13.1 2.0 56 3.4 2.0 4.4 1 1 0 1 1 1 0 Mitochondrial biogenesis AIM24 3-PAP PF12578.8 RUS79946.1 - 1.5 8.6 9.7 3.2 7.5 1.0 2.6 1 1 1 2 2 2 0 Myotubularin-associated protein LRR_8 PF13855.6 RUS79948.1 - 1.4e-38 130.4 58.1 1.9e-12 46.8 5.3 10.1 7 3 2 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 RUS79948.1 - 4.4e-23 81.0 65.2 6e-05 23.3 1.2 11.8 6 5 6 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS79948.1 - 1.5e-09 37.6 14.6 0.00053 19.5 0.4 4.3 3 1 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 RUS79948.1 - 1.5e-05 24.9 61.2 0.9 10.3 0.2 16.4 18 2 0 18 18 18 6 Leucine Rich Repeat LRR_6 PF13516.6 RUS79948.1 - 0.099 12.7 0.3 0.099 12.7 0.3 12.8 15 0 0 15 15 15 0 Leucine Rich repeat Lectin_C PF00059.21 RUS79950.1 - 2.8e-06 28.0 0.1 4.7e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS79950.1 - 0.0021 18.0 0.9 0.0021 18.0 0.9 2.1 1 1 1 2 2 2 1 PAN domain PAN_3 PF08277.12 RUS79950.1 - 0.0024 17.6 2.6 0.0051 16.6 0.6 2.2 2 0 0 2 2 2 1 PAN-like domain Usp PF00582.26 RUS79951.1 - 4.3e-29 101.8 0.1 6.2e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family DNA_photolyase PF00875.18 RUS79951.1 - 0.062 13.3 0.1 0.33 11.0 0.1 1.9 1 1 1 2 2 2 0 DNA photolyase DUF523 PF04463.12 RUS79951.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF523) WIF PF02019.18 RUS79952.1 - 4.6e-29 100.7 0.0 6.4e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.13 RUS79952.1 - 6.6e-08 32.8 31.9 2.5e-05 24.5 9.9 2.3 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 RUS79952.1 - 4.4e-06 26.9 28.8 0.00012 22.3 9.9 2.4 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS79952.1 - 0.00041 20.9 7.3 0.00041 20.9 7.3 2.4 2 0 0 2 2 2 1 Human growth factor-like EGF DUF3140 PF11338.8 RUS79952.1 - 0.62 10.5 7.7 3 8.3 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) Laminin_EGF PF00053.24 RUS79952.1 - 1.1 9.4 19.6 12 6.1 6.4 2.4 1 1 1 2 2 2 0 Laminin EGF domain DUF2207 PF09972.9 RUS79952.1 - 2.1 7.0 7.7 2.8 6.6 7.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 RUS79954.1 - 4.2e-62 209.9 0.1 1.6e-61 208.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS79954.1 - 1.5e-30 106.4 0.0 3.2e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS79954.1 - 2.2e-09 37.0 4.0 2.8e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 RUS79954.1 - 0.0096 16.6 0.5 0.036 14.8 0.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 RUS79954.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 RUS79954.1 - 0.03 14.3 0.0 0.03 14.3 0.0 3.1 4 0 0 4 4 4 0 Phosphotransferase enzyme family Leucyl-specific PF14795.6 RUS79954.1 - 0.07 13.2 8.8 0.54 10.4 0.2 4.2 3 1 0 3 3 3 0 Leucine-tRNA synthetase-specific domain Spc7 PF08317.11 RUS79954.1 - 0.097 11.5 81.1 0.032 13.1 24.2 4.2 2 2 2 4 4 4 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 RUS79954.1 - 0.39 10.9 89.5 0.94 9.7 18.4 6.0 2 2 4 6 6 6 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 RUS79954.1 - 0.49 10.4 87.4 0.033 14.2 19.1 5.4 2 2 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.27 RUS79955.1 - 4.4e-09 37.0 0.0 8.8e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RUS79955.1 - 0.00028 20.8 0.0 0.00034 20.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RUS79955.1 - 0.22 11.8 0.2 1.6 9.0 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4291 PF14124.6 RUS79956.1 - 6.1e-63 211.9 0.6 8.2e-63 211.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) zf-RING_2 PF13639.6 RUS79957.1 - 1e-12 48.2 6.1 1e-12 48.2 6.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS79957.1 - 1.5e-10 40.6 2.5 1.5e-10 40.6 2.5 2.6 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS79957.1 - 2e-08 33.9 6.4 6.6e-08 32.3 6.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS79957.1 - 2e-07 30.8 4.1 2e-07 30.8 4.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ZNRF_3_ecto PF18212.1 RUS79957.1 - 2.3e-07 30.8 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_UBOX PF13445.6 RUS79957.1 - 2.9e-07 30.4 3.7 1.2e-06 28.4 3.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS79957.1 - 4.1e-07 29.8 2.8 1.2e-06 28.4 2.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS79957.1 - 1.3e-06 28.6 7.8 1.1e-05 25.6 7.8 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 RUS79957.1 - 0.00017 21.3 3.2 0.00017 21.3 3.2 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS79957.1 - 0.00043 20.1 4.4 0.0012 18.7 4.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 RUS79957.1 - 0.0072 16.3 1.5 0.022 14.8 1.5 1.9 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 RUS79957.1 - 0.036 14.1 1.6 0.11 12.6 0.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-E2_D PF14460.6 RUS79957.1 - 0.066 12.9 0.0 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family D RasGEF_N PF00618.20 RUS79958.1 - 0.024 14.9 0.3 0.042 14.1 0.3 1.4 1 0 0 1 1 1 0 RasGEF N-terminal motif Homeobox_KN PF05920.11 RUS79960.1 - 4e-16 58.6 0.3 8e-16 57.7 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS79960.1 - 1.3e-06 28.1 0.8 2.4e-06 27.3 0.8 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 RUS79960.1 - 0.015 15.9 0.2 0.12 13.0 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DUF4503 PF14951.6 RUS79961.1 - 0.067 11.7 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) RGS_DHEX PF18148.1 RUS79962.1 - 0.025 14.7 1.5 0.067 13.3 0.0 2.4 2 1 1 3 3 3 0 Regulator of G-protein signalling DHEX domain Erythro-docking PF09277.11 RUS79962.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking Clathrin_lg_ch PF01086.17 RUS79962.1 - 0.14 12.2 4.1 0.21 11.6 4.1 1.3 1 0 0 1 1 1 0 Clathrin light chain Crust_neurohorm PF01147.17 RUS79962.1 - 6 6.8 7.7 2.7 7.9 2.3 2.7 3 0 0 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family HMG_box PF00505.19 RUS79963.1 - 1.1e-14 54.6 0.0 2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS79963.1 - 6e-05 23.6 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF668 PF05003.12 RUS79966.1 - 3.4e-05 24.2 1.5 0.037 14.5 0.5 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF668) DUF896 PF05979.12 RUS79966.1 - 6.9e-05 22.6 9.2 2.2 8.2 0.1 5.2 1 1 4 5 5 5 3 Bacterial protein of unknown function (DUF896) Ints3 PF10189.9 RUS79966.1 - 0.00067 19.0 0.3 0.23 10.7 0.1 2.6 1 1 1 2 2 2 2 Integrator complex subunit 3 MgtE_N PF03448.17 RUS79966.1 - 0.0012 19.4 0.7 0.006 17.2 0.5 1.7 1 1 0 1 1 1 1 MgtE intracellular N domain TrmO_C PF18389.1 RUS79966.1 - 0.0014 18.7 1.2 3.6 7.8 0.1 3.0 1 1 2 3 3 3 2 TrmO C-terminal domain Herpes_UL17 PF04559.12 RUS79966.1 - 0.0054 15.6 0.5 0.092 11.5 0.5 2.1 1 1 0 1 1 1 1 Herpesvirus UL17 protein DUF445 PF04286.12 RUS79966.1 - 0.012 15.5 1.2 0.013 15.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Vps39_2 PF10367.9 RUS79966.1 - 0.017 15.6 3.7 0.85 10.1 1.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 GerPC PF10737.9 RUS79966.1 - 0.018 15.1 1.2 0.024 14.7 1.2 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC Tam41_Mmp37 PF09139.11 RUS79966.1 - 0.029 13.8 1.5 0.036 13.5 1.5 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DUF4655 PF15548.6 RUS79966.1 - 0.037 13.0 5.1 0.043 12.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) NYD-SP28 PF14772.6 RUS79966.1 - 0.039 14.0 1.8 3.2 7.9 0.2 2.2 1 1 1 2 2 2 0 Sperm tail STAT_int PF02865.17 RUS79966.1 - 0.04 14.4 1.6 0.82 10.1 0.6 2.3 1 1 1 2 2 2 0 STAT protein, protein interaction domain Minor_tail_Z PF06763.11 RUS79966.1 - 0.049 13.4 1.5 5 6.9 0.1 2.3 1 1 1 2 2 2 0 Prophage minor tail protein Z (GPZ) Flu_B_NS1 PF02942.14 RUS79966.1 - 0.073 12.1 0.3 4.1 6.4 0.0 2.0 1 1 1 2 2 2 0 Influenza B non-structural protein (NS1) CEL_III_C PF18054.1 RUS79966.1 - 0.17 11.9 0.4 0.32 11.0 0.4 1.6 1 1 0 1 1 1 0 CEL-III C-terminal RTC4 PF14474.6 RUS79966.1 - 0.26 11.5 2.6 30 4.8 0.1 2.9 1 1 2 3 3 3 0 RTC4-like domain Pex19 PF04614.12 RUS79967.1 - 5.8e-33 114.7 2.1 5.8e-33 114.7 2.1 1.8 1 1 1 2 2 2 1 Pex19 protein family Globin PF00042.22 RUS79967.1 - 0.099 13.2 0.2 1 9.9 0.1 2.4 3 0 0 3 3 3 0 Globin Phage_int_SAM_1 PF02899.17 RUS79967.1 - 0.18 12.1 0.1 0.55 10.6 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain T2SSM PF04612.12 RUS79967.1 - 0.23 11.5 1.5 0.75 9.8 0.9 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M SDA1 PF05285.12 RUS79968.1 - 0.0024 17.4 70.6 0.0031 17.0 70.6 1.1 1 0 0 1 1 1 1 SDA1 Neur_chan_memb PF02932.16 RUS79968.1 - 0.016 15.2 6.4 0.022 14.8 6.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 RUS79968.1 - 4.2 6.7 61.7 5.7e+02 -0.4 61.7 2.1 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) IMCp PF12314.8 RUS79969.1 - 0.0022 18.2 33.1 0.068 13.5 9.1 3.1 1 1 1 3 3 3 3 Inner membrane complex protein SelB-wing_3 PF09107.11 RUS79969.1 - 2.6 7.8 33.6 31 4.3 0.1 9.1 2 2 8 10 10 10 0 Elongation factor SelB, winged helix Presenilin PF01080.17 RUS79970.1 - 2.3 6.9 10.0 2.4 6.8 10.0 1.0 1 0 0 1 1 1 0 Presenilin FTZ PF03867.14 RUS79970.1 - 4.1 6.9 23.4 4.9 6.6 23.4 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Pex14_N PF04695.13 RUS79970.1 - 9.6 6.8 21.4 13 6.4 21.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.27 RUS79972.1 - 8.3e-48 162.8 1.3 1.2e-47 162.3 0.3 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chordopox_A33R PF05966.12 RUS79973.1 - 0.019 14.2 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein UL45 PF05473.12 RUS79973.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like GSDH PF07995.11 RUS79975.1 - 0.0033 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase TFIID-31kDa PF02291.15 RUS79976.1 - 0.018 15.1 6.1 26 4.9 0.0 5.1 1 1 5 6 6 6 0 Transcription initiation factor IID, 31kD subunit SHR-BD PF06650.12 RUS79976.1 - 0.048 13.0 0.7 0.11 11.8 0.7 1.7 1 1 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 PAP_PilO PF06864.12 RUS79976.1 - 0.16 10.8 2.0 0.69 8.7 1.5 2.0 1 1 1 2 2 2 0 Pilin accessory protein (PilO) CUB PF00431.20 RUS79977.1 - 2.4e-65 217.8 0.0 1.8e-32 111.9 0.0 2.0 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 RUS79977.1 - 0.013 15.3 0.3 3.4 7.4 0.1 2.9 2 2 0 2 2 2 0 CUB-like domain LicD PF04991.13 RUS79979.1 - 1.7e-15 57.8 6.2 2.3e-11 44.3 2.2 3.0 1 1 1 2 2 2 2 LicD family PDR_assoc PF08370.11 RUS79980.1 - 0.2 11.4 2.5 2.1 8.1 0.7 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Cpn60_TCP1 PF00118.24 RUS79981.1 - 5e-169 563.0 7.1 5.7e-169 562.8 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1894 PF08979.11 RUS79981.1 - 0.022 15.1 0.5 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) DUF1725 PF08333.11 RUS79981.1 - 0.048 13.3 0.4 0.13 12.0 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) PAM2 PF07145.15 RUS79982.1 - 3e-05 23.4 0.1 5.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Arrestin_N PF00339.29 RUS79983.1 - 6.5e-39 133.3 0.2 6.1e-38 130.2 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS79983.1 - 1.6e-21 77.1 0.0 2.6e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 RUS79983.1 - 0.00062 18.8 0.0 0.0014 17.7 0.0 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 RUS79983.1 - 0.0093 15.2 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 Rgp1 LDB19 PF13002.7 RUS79983.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like His_Phos_2 PF00328.22 RUS79984.1 - 3.2e-28 99.2 1.1 3.1e-25 89.3 0.1 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cyt_c_ox_IV PF12270.8 RUS79984.1 - 0.049 13.8 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV RVT_1 PF00078.27 RUS79985.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Filament PF00038.21 RUS79986.1 - 7.4e-68 229.4 50.6 5.9e-40 137.8 23.4 2.2 1 1 1 2 2 2 2 Intermediate filament protein LTD PF00932.19 RUS79986.1 - 3e-14 53.3 0.3 5.6e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Lamin Tail Domain FPP PF05911.11 RUS79986.1 - 1.6e-05 23.4 43.3 2.7e-05 22.6 10.2 3.1 1 1 1 3 3 3 2 Filament-like plant protein, long coiled-coil Tup_N PF08581.10 RUS79986.1 - 3.2e-05 24.2 38.6 0.039 14.3 2.4 6.3 2 2 3 5 5 5 2 Tup N-terminal Lebercilin PF15619.6 RUS79986.1 - 0.00037 20.2 6.0 0.00037 20.2 6.0 3.8 2 2 0 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease Myosin_tail_1 PF01576.19 RUS79986.1 - 0.0011 16.9 28.4 0.0011 16.9 28.4 2.1 1 1 1 2 2 2 1 Myosin tail ABC_tran_CTD PF16326.5 RUS79986.1 - 0.0013 18.9 2.9 0.0013 18.9 2.9 6.1 4 2 3 7 7 7 2 ABC transporter C-terminal domain DUF4407 PF14362.6 RUS79986.1 - 0.0023 17.4 7.1 0.0023 17.4 7.1 2.9 2 2 0 2 2 2 1 Domain of unknown function (DUF4407) TACC_C PF05010.14 RUS79986.1 - 0.003 17.4 36.1 0.23 11.2 19.9 3.0 2 1 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BST2 PF16716.5 RUS79986.1 - 0.0096 16.5 1.0 0.0096 16.5 1.0 5.4 2 2 4 6 6 6 1 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 RUS79986.1 - 0.0099 16.1 3.5 0.0099 16.1 3.5 4.3 2 1 2 4 4 3 1 Fibrinogen alpha/beta chain family MAD PF05557.13 RUS79986.1 - 0.011 14.2 45.7 0.033 12.6 11.5 2.4 2 1 0 2 2 2 0 Mitotic checkpoint protein DUF724 PF05266.14 RUS79986.1 - 0.011 15.6 2.4 0.011 15.6 2.4 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 RUS79986.1 - 0.015 15.3 14.5 0.47 10.5 0.1 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2576 PF10845.8 RUS79986.1 - 0.023 14.3 0.2 0.11 12.1 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF4140 PF13600.6 RUS79986.1 - 0.043 14.3 1.2 0.043 14.3 1.2 5.8 2 2 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) Rootletin PF15035.6 RUS79986.1 - 0.049 13.7 44.0 0.012 15.6 10.6 4.0 1 1 4 5 5 5 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 RUS79986.1 - 0.05 13.7 50.0 0.042 13.9 8.6 4.2 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 RUS79986.1 - 0.056 14.2 23.1 0.082 13.6 7.4 4.9 2 2 2 5 5 5 0 Occludin homology domain Spc7 PF08317.11 RUS79986.1 - 0.063 12.2 47.4 0.011 14.6 7.8 3.8 2 2 2 4 4 4 0 Spc7 kinetochore protein ATG16 PF08614.11 RUS79986.1 - 0.086 13.1 54.8 0.49 10.6 7.8 4.9 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) YabA PF06156.13 RUS79986.1 - 0.092 13.4 33.6 2 9.1 4.7 5.8 2 2 3 5 5 5 0 Initiation control protein YabA Golgin_A5 PF09787.9 RUS79986.1 - 0.11 12.0 47.4 0.5 9.8 15.6 3.5 1 1 1 3 3 3 0 Golgin subfamily A member 5 PKcGMP_CC PF16808.5 RUS79986.1 - 0.16 11.8 0.2 0.16 11.8 0.2 5.3 5 2 1 6 6 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 RUS79986.1 - 0.23 11.6 46.5 0.75 9.9 15.3 4.7 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 RUS79986.1 - 0.25 11.4 27.6 0.2 11.7 1.0 5.5 2 2 3 6 6 6 0 Protein of unknown function (DUF1664) GPS2_interact PF15784.5 RUS79986.1 - 0.29 11.6 20.3 0.22 12.0 0.4 5.0 3 2 1 4 4 4 0 G-protein pathway suppressor 2-interacting domain Pox_A_type_inc PF04508.12 RUS79986.1 - 0.42 10.6 11.4 2.9 7.9 0.2 5.9 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat GAS PF13851.6 RUS79986.1 - 0.52 9.6 45.7 0.021 14.2 7.1 4.5 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding Tho2 PF11262.8 RUS79986.1 - 1 8.5 23.3 0.013 14.7 2.6 3.5 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 RUS79986.1 - 1 9.5 41.9 0.24 11.5 9.1 3.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 RUS79986.1 - 1.1 9.3 51.4 0.23 11.5 11.8 4.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 RUS79986.1 - 1.1 9.6 49.6 0.66 10.3 7.6 4.5 3 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4094 PF13334.6 RUS79986.1 - 1.1 9.7 16.5 39 4.7 0.1 5.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) DUF948 PF06103.11 RUS79986.1 - 1.2 9.5 13.8 28 5.1 2.2 5.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 RUS79986.1 - 1.5 9.4 55.2 0.59 10.7 11.0 5.0 2 2 1 4 4 4 0 Apg6 coiled-coil region DHR10 PF18595.1 RUS79986.1 - 1.7 8.7 47.4 0.083 13.0 6.1 5.6 2 2 3 5 5 5 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 RUS79986.1 - 3.3 8.2 16.3 8.3 7.0 0.1 5.0 5 1 0 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 RUS79986.1 - 3.5 6.9 44.4 0.82 8.9 3.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 RUS79986.1 - 3.7 7.8 44.1 0.5 10.6 8.8 4.1 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 RAMPs PF03787.15 RUS79986.1 - 5.6 6.9 6.1 16 5.5 6.1 1.7 1 1 0 1 1 1 0 RAMP superfamily Bacillus_HBL PF05791.11 RUS79986.1 - 5.8 6.7 19.1 0.47 10.2 1.8 3.7 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) TMPIT PF07851.13 RUS79986.1 - 7 5.8 22.7 3.1 6.9 3.4 3.2 2 2 1 3 3 3 0 TMPIT-like protein KASH_CCD PF14662.6 RUS79986.1 - 9.2 6.0 48.6 8.6 6.1 12.0 3.8 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH RNase_HII PF01351.18 RUS79987.1 - 8.1e-52 176.0 0.0 1e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII MNNL PF07657.13 RUS79988.1 - 1.8e-07 31.1 0.1 3.8e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 N terminus of Notch ligand DSL PF01414.19 RUS79989.1 - 0.0011 19.2 0.2 0.0018 18.5 0.2 1.4 1 0 0 1 1 1 1 Delta serrate ligand Pyr_redox_3 PF13738.6 RUS79989.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HGTP_anticodon PF03129.20 RUS79990.1 - 8.8e-20 70.7 0.0 2.6e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RUS79990.1 - 6.6e-10 39.2 0.0 2.5e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 RUS79990.1 - 6.3e-08 32.6 4.3 6.3e-08 32.6 4.3 2.2 2 0 0 2 2 2 1 WHEP-TRS domain YlaC PF10777.9 RUS79990.1 - 0.0091 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane protein YlaC LPMO_10 PF03067.15 RUS79991.1 - 1.1e-17 65.4 0.0 1.4e-17 65.1 0.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HTH_23 PF13384.6 RUS79993.1 - 1.4e-07 31.1 2.0 0.46 10.3 0.5 3.7 4 0 0 4 4 4 3 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 RUS79993.1 - 1.8e-05 24.9 0.1 2.9 8.1 0.0 4.3 4 0 0 4 4 4 3 Helix-turn-helix of insertion element transposase HTH_28 PF13518.6 RUS79993.1 - 7.9e-05 22.7 1.8 1.7 8.9 0.4 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 RUS79993.1 - 0.0003 21.1 0.3 12 6.3 0.0 4.3 4 0 0 4 4 4 2 Transposase HTH_29 PF13551.6 RUS79993.1 - 0.017 15.2 2.1 4.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Winged helix-turn helix Hrs_helical PF12210.8 RUS79993.1 - 0.06 13.9 0.2 5.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CAAP1 PF15335.6 RUS79994.1 - 8.7e-19 67.8 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 DUF4208 PF13907.6 RUS79994.1 - 0.026 15.0 0.1 0.064 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) FCP1_C PF09309.10 RUS79994.1 - 0.71 9.7 10.5 0.1 12.5 6.2 1.7 1 1 0 2 2 2 0 FCP1, C-terminal SNARE_assoc PF09335.11 RUS79997.1 - 2.1e-20 73.4 5.7 2.1e-20 73.4 5.7 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1449 PF07290.11 RUS79997.1 - 0.022 14.4 0.1 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) DUF4407 PF14362.6 RUS79997.1 - 2 7.7 3.6 2 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1065 PF06358.11 RUS79998.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) C_tripleX PF02363.19 RUS79999.1 - 2.2 8.8 8.2 4.3 7.8 0.4 4.2 4 0 0 4 4 4 0 Cysteine rich repeat Ubie_methyltran PF01209.18 RUS80000.1 - 7.5e-84 280.7 0.0 8.5e-84 280.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 RUS80000.1 - 3.4e-16 59.7 0.0 6.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS80000.1 - 1.3e-15 57.8 0.0 4.2e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS80000.1 - 1.7e-10 40.9 0.0 2.5e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS80000.1 - 5.6e-08 33.4 0.0 1e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS80000.1 - 3.5e-06 26.9 0.0 7e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS80000.1 - 0.026 14.1 0.0 0.062 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain ADH_zinc_N PF00107.26 RUS80000.1 - 0.037 14.0 0.0 0.069 13.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 RUS80000.1 - 0.039 13.8 0.0 0.26 11.1 0.0 2.1 3 0 0 3 3 3 0 Hypothetical methyltransferase DUF2069 PF09842.9 RUS80001.1 - 0.7 10.1 36.9 34 4.7 0.2 8.7 2 2 7 9 9 9 0 Predicted membrane protein (DUF2069) Thioredoxin_4 PF13462.6 RUS80002.1 - 3e-06 27.5 0.0 0.00099 19.3 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Filo_VP35 PF02097.15 RUS80002.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 MazG-like PF12643.7 RUS80003.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 RUS80003.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Aminotran_4 PF01063.19 RUS80005.1 - 3.9e-23 82.5 0.0 4.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aminotran_4 PF01063.19 RUS80006.1 - 1.4e-25 90.4 0.0 1.9e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV pPIWI_RE_X PF13111.6 RUS80006.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain Aminotran_4 PF01063.19 RUS80007.1 - 4.7e-17 62.6 0.0 6.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Anp1 PF03452.14 RUS80008.1 - 0.063 12.7 0.8 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Anp1 Ion_trans PF00520.31 RUS80008.1 - 0.3 10.3 6.9 0.068 12.4 3.2 1.7 2 0 0 2 2 2 0 Ion transport protein AC_N PF16214.5 RUS80008.1 - 3.4 6.7 5.5 7.6 5.5 5.5 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3649 PF12365.8 RUS80009.1 - 2.6 7.8 15.0 18 5.2 0.1 6.2 2 2 6 9 9 9 0 Protein of unknown function (DUF3649) Rbx_binding PF18113.1 RUS80010.1 - 0.0017 18.1 0.4 4.7 7.1 0.0 5.0 5 1 1 6 6 6 1 Rubredoxin binding C-terminal domain CPCFC PF17223.3 RUS80010.1 - 2.3 8.0 30.6 65 3.4 0.5 11.3 13 4 3 16 16 16 0 Cuticle protein CPCFC SUKH-3 PF14433.6 RUS80011.1 - 0.01 16.3 6.4 60 4.1 0.0 7.1 1 1 2 4 4 4 0 SUKH-3 immunity protein DUF1375 PF07119.12 RUS80011.1 - 1.4 9.3 6.1 49 4.4 0.2 5.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1375) Ank PF00023.30 RUS80014.1 - 1.2e-12 47.6 0.2 0.00047 20.5 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 RUS80014.1 - 1.6e-12 47.8 0.0 3.7e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS80014.1 - 1.3e-10 40.6 4.1 0.0017 18.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RUS80014.1 - 2.3e-10 40.5 0.2 0.0021 18.4 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS80014.1 - 5.6e-10 39.5 0.2 0.001 19.6 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DNA_pol_B_palm PF14792.6 RUS80014.1 - 0.16 12.2 1.5 20 5.4 0.1 2.3 1 1 1 2 2 2 0 DNA polymerase beta palm PMG PF05287.12 RUS80015.1 - 0.078 13.0 15.0 0.14 12.2 2.5 2.9 1 1 0 2 2 2 0 PMG protein Ephrin_lbd PF01404.19 RUS80015.1 - 2.5 8.1 5.3 1.2e+02 2.6 0.0 4.2 2 1 4 6 6 6 0 Ephrin receptor ligand binding domain DUF3128 PF11326.8 RUS80015.1 - 4.5 7.7 10.8 45 4.5 1.9 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3128) DUF1842 PF08896.10 RUS80016.1 - 5.3e-05 23.5 8.4 2.7 8.3 0.2 5.8 2 1 2 5 5 5 4 Domain of unknown function (DUF1842) DUF4985 PF16373.5 RUS80016.1 - 3.2 8.3 3.8 1.3e+02 3.1 0.1 4.2 2 2 4 6 6 6 0 Domain of unknown function DUF5073 PF16817.5 RUS80016.1 - 7.2 6.7 26.2 33 4.6 0.1 7.1 2 2 7 9 9 9 0 Domain of unknown function (DUF5073) PhoU PF01895.19 RUS80017.1 - 0.097 13.1 14.1 43 4.7 0.5 5.8 1 1 2 3 3 3 0 PhoU domain zf-C2HC5 PF06221.13 RUS80019.1 - 0.064 13.3 19.9 36 4.4 0.3 6.9 1 1 6 7 7 7 0 Putative zinc finger motif, C2HC5-type YacG PF03884.14 RUS80019.1 - 0.2 11.4 14.0 4.7 7.0 0.6 4.2 3 1 0 4 4 4 0 DNA gyrase inhibitor YacG Atrophin-1 PF03154.15 RUS80019.1 - 8.5 4.5 28.4 1.2 7.3 15.8 2.0 1 1 1 2 2 2 0 Atrophin-1 family Methyltransf_16 PF10294.9 RUS80020.1 - 6.1e-12 45.6 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 RUS80020.1 - 3e-06 27.1 0.0 6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS80020.1 - 4.4e-05 24.1 0.0 8.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS80020.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS80020.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 RUS80020.1 - 0.0025 17.5 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RUS80020.1 - 0.0092 16.6 0.0 0.047 14.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RUS80020.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 RUS80020.1 - 0.058 14.1 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-TFIIIC PF12660.7 RUS80021.1 - 0.013 15.4 7.9 0.013 15.4 7.9 2.2 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex DCB PF16213.5 RUS80021.1 - 0.041 13.6 0.5 0.084 12.5 0.5 1.6 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 zf-ribbon_3 PF13248.6 RUS80021.1 - 0.064 12.7 6.1 1.2 8.7 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain ATPase-cat_bd PF12156.8 RUS80021.1 - 0.46 11.3 5.5 49 4.7 5.2 2.5 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DUF836 PF05768.14 RUS80022.1 - 2.2e-13 50.4 0.0 3.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) HTH_9 PF08221.11 RUS80023.1 - 3.6e-22 78.2 10.5 4.1e-18 65.2 0.4 5.0 5 1 0 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 RUS80023.1 - 1.1e-21 77.7 2.2 5.1e-21 75.6 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 RUS80023.1 - 5.1e-05 23.1 3.6 0.05 13.5 0.1 3.4 4 0 0 4 4 4 2 TFIIE alpha subunit CvfB_WH PF17783.1 RUS80023.1 - 0.013 15.3 1.0 0.079 12.8 0.0 2.8 3 0 0 3 3 3 0 CvfB-like winged helix domain TrmB PF01978.19 RUS80023.1 - 0.017 15.0 1.3 4.7 7.2 0.0 3.6 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB IF2_N PF04760.15 RUS80024.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GOLD_2 PF13897.6 RUS80025.1 - 6.3 7.3 6.4 2.3 8.7 2.0 2.2 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking NUDIX PF00293.28 RUS80026.1 - 2.4e-18 66.4 0.0 4.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain WW_1 PF18507.1 RUS80026.1 - 1.4 8.7 3.4 6 6.7 0.4 2.6 2 0 0 2 2 2 0 WW domain TatD_DNase PF01026.21 RUS80029.1 - 2.6e-33 115.5 0.0 3.6e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Myb_DNA-binding PF00249.31 RUS80030.1 - 1.2e-10 41.4 0.1 2.5e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 RUS80030.1 - 7.5e-06 26.2 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 RUS80030.1 - 0.00035 20.8 0.0 0.0013 19.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4042 PF13251.6 RUS80031.1 - 3.5e-60 202.8 1.2 2.7e-59 199.9 1.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 RUS80031.1 - 2.3e-12 47.1 0.8 0.0046 17.3 0.2 6.4 6 2 0 6 6 6 3 HEAT repeats HEAT PF02985.22 RUS80031.1 - 2.2e-09 36.7 23.8 0.046 14.0 0.0 10.4 11 1 0 12 12 11 4 HEAT repeat Adaptin_N PF01602.20 RUS80031.1 - 1.5e-06 27.1 5.2 0.0045 15.6 0.5 4.3 4 1 0 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 RUS80031.1 - 2.4e-06 27.9 8.4 7.6 7.2 0.0 7.5 5 3 1 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 RUS80031.1 - 0.00043 20.4 2.0 1.8 8.8 0.0 4.7 5 1 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 RUS80031.1 - 0.0079 16.3 0.7 1.9 8.6 0.0 4.0 3 0 0 3 3 3 1 Exportin 1-like protein Cnd1 PF12717.7 RUS80031.1 - 0.36 10.9 5.0 13 5.8 0.0 5.3 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RUS80031.1 - 0.41 10.8 10.2 0.22 11.6 0.1 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 RUS80031.1 - 0.61 10.9 3.1 63 4.7 0.0 4.9 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 RUS80031.1 - 9.4 5.9 8.7 1.8 8.3 1.3 3.2 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Spc7 PF08317.11 RUS80036.1 - 0.0026 16.7 20.0 0.0026 16.7 20.0 4.5 2 1 2 4 4 4 1 Spc7 kinetochore protein SUI1 PF01253.22 RUS80037.1 - 9.5e-20 70.9 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 eRF1_1 PF03463.15 RUS80038.1 - 9.6e-51 171.1 0.7 1.5e-50 170.5 0.7 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 RUS80038.1 - 2e-32 112.3 0.0 3.1e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RUS80038.1 - 6.7e-25 87.8 0.0 2.2e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 HTH_57 PF18679.1 RUS80038.1 - 0.032 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 ThcOx helix turn helix domain EST1 PF10374.9 RUS80038.1 - 0.13 12.9 0.1 0.88 10.2 0.0 2.1 1 1 1 2 2 2 0 Telomerase activating protein Est1 Antistasin PF02822.14 RUS80040.1 - 6.8e-06 26.6 9.7 6.8e-06 26.6 9.7 2.3 2 0 0 2 2 2 2 Antistasin family DUF3924 PF13062.6 RUS80041.1 - 0.17 11.8 0.0 2.1e+02 1.9 0.0 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF3924) cNMP_binding PF00027.29 RUS80042.1 - 3.1e-08 33.6 0.0 1.8e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ANF_receptor PF01094.28 RUS80043.1 - 9.6e-57 192.7 0.0 1.5e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region VIR_N PF15912.5 RUS80044.1 - 0.013 15.1 3.6 0.012 15.2 3.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AAA_11 PF13086.6 RUS80044.1 - 0.02 14.7 18.9 0.023 14.5 18.9 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 RUS80044.1 - 0.024 14.7 9.5 0.026 14.6 9.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCSAP PF15748.5 RUS80044.1 - 0.028 14.6 30.3 0.035 14.3 30.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SAPS PF04499.15 RUS80044.1 - 0.047 12.5 9.5 0.051 12.3 9.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2828 PF11443.8 RUS80044.1 - 0.15 10.1 27.2 0.18 9.9 27.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 RUS80044.1 - 0.25 10.8 10.7 0.29 10.5 10.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DDHD PF02862.17 RUS80044.1 - 0.27 11.4 13.5 0.42 10.7 13.5 1.3 1 0 0 1 1 1 0 DDHD domain DUF4776 PF16003.5 RUS80044.1 - 0.44 9.5 35.5 0.55 9.2 35.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SID-1_RNA_chan PF13965.6 RUS80044.1 - 0.62 8.4 4.3 0.62 8.4 4.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2052 PF09747.9 RUS80044.1 - 0.8 9.8 19.5 1 9.4 19.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 RUS80044.1 - 2.2 7.2 27.6 2.8 6.9 27.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 RUS80044.1 - 2.7 6.9 30.1 3.3 6.6 30.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 RUS80044.1 - 3.2 5.9 29.2 4 5.6 29.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 RUS80044.1 - 3.5 7.9 50.0 5.9 7.2 50.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dsh_C PF12316.8 RUS80044.1 - 3.8 7.9 7.3 5.1 7.4 7.3 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 RUS80044.1 - 4 7.2 38.4 5.1 6.8 38.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 RUS80044.1 - 6.2 6.9 27.5 9.1 6.3 27.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF913 PF06025.12 RUS80044.1 - 7.1 5.5 16.4 8.3 5.3 16.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4228 PF14009.6 RUS80044.1 - 9.6 6.6 19.5 13 6.1 19.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ras PF00071.22 RUS80045.1 - 3e-33 114.7 0.1 3.4e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS80045.1 - 1.4e-09 38.2 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS80045.1 - 7.5e-05 22.7 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 RUS80045.1 - 0.00033 20.2 0.1 0.00057 19.4 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS80045.1 - 0.001 19.1 0.0 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS80045.1 - 0.0014 19.1 0.0 0.0021 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 RUS80045.1 - 0.0018 17.8 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 RUS80045.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 RUS80045.1 - 0.086 12.6 0.3 2.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 RUS80045.1 - 0.12 13.0 0.1 0.16 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS80045.1 - 0.12 12.6 0.0 0.48 10.7 0.0 1.9 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 RUS80045.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Ras PF00071.22 RUS80046.1 - 4.8e-19 68.5 0.0 8.4e-19 67.7 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS80046.1 - 0.00073 19.7 0.0 0.0079 16.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS80046.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Death PF00531.22 RUS80047.1 - 7.4e-13 48.5 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Death domain Staph_opine_DH PF10100.9 RUS80047.1 - 0.072 11.7 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase EF-hand_1 PF00036.32 RUS80047.1 - 0.11 12.1 0.1 3 7.6 0.0 2.8 2 0 0 2 2 2 0 EF hand FAM183 PF14886.6 RUS80048.1 - 2.6 8.8 8.4 73 4.2 5.1 3.6 1 1 1 2 2 2 0 FAM183A and FAM183B related CAMSAP_CC1 PF17095.5 RUS80048.1 - 6.4 6.7 11.3 26 4.8 0.2 4.6 5 0 0 5 5 5 0 Spectrin-binding region of Ca2+-Calmodulin Histone PF00125.24 RUS80049.1 - 5.4e-19 68.9 0.0 6.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 RUS80049.1 - 1.3e-13 50.5 0.4 2.4e-13 49.6 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 RUS80049.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CAF1 PF04857.20 RUS80050.1 - 2.9e-52 177.8 0.1 3.8e-52 177.4 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 RUS80050.1 - 1.7e-28 98.4 0.4 3.3e-28 97.5 0.4 1.5 1 0 0 1 1 1 1 RNA binding domain RRM_1 PF00076.22 RUS80050.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cortex-I_coil PF09304.10 RUS80050.1 - 0.12 12.6 2.6 1.4 9.1 0.7 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Cation_efflux PF01545.21 RUS80052.1 - 2.8e-25 89.2 5.5 3.6e-25 88.9 5.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RUS80052.1 - 1.8e-10 40.8 0.5 3.8e-10 39.7 0.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1129 PF06570.11 RUS80052.1 - 0.047 13.2 1.1 0.072 12.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Abhydrolase_9_N PF15420.6 RUS80052.1 - 0.15 12.0 6.1 0.11 12.4 3.9 1.7 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus FAD-oxidase_C PF02913.19 RUS80053.1 - 3.8e-61 206.9 0.0 4.9e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RUS80053.1 - 1.5e-34 118.7 0.5 2.3e-34 118.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain KbaA PF14089.6 RUS80055.1 - 0.063 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation DnaJ PF00226.31 RUS80056.1 - 2.2e-27 95.0 1.7 2.2e-27 95.0 1.7 1.8 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 RUS80056.1 - 0.052 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin eIF-5a PF01287.20 RUS80057.1 - 9.9e-17 60.8 0.1 1.5e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RUS80057.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DUF4570 PF15134.6 RUS80058.1 - 2.8e-13 49.9 0.3 3.8e-13 49.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Alk_phosphatase PF00245.20 RUS80059.1 - 4.7e-113 378.3 0.1 1.1e-112 377.1 0.1 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS80059.1 - 0.0059 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily CG-1 PF03859.16 RUS80061.1 - 6.2e-40 135.6 0.7 6.2e-40 135.6 0.7 2.4 2 0 0 2 2 2 1 CG-1 domain HTH_Tnp_Tc5 PF03221.16 RUS80061.1 - 0.00043 20.3 0.2 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain IQ PF00612.27 RUS80061.1 - 0.0019 17.8 20.4 0.027 14.3 1.0 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank_2 PF12796.7 RUS80061.1 - 0.01 16.4 0.3 0.13 12.8 0.1 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS80061.1 - 0.12 12.8 1.5 0.19 12.1 0.2 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS80061.1 - 1.8 9.4 4.2 11 7.0 0.3 3.1 3 0 0 3 3 3 0 Ankyrin repeat DUF2408 PF10303.9 RUS80062.1 - 0.002 18.7 3.8 0.0022 18.6 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CAMP_factor PF07373.11 RUS80062.1 - 0.0037 16.9 1.0 0.0046 16.6 1.0 1.1 1 0 0 1 1 1 1 CAMP factor (Cfa) FANCI_S4 PF14678.6 RUS80062.1 - 0.013 14.6 1.7 0.016 14.3 1.7 1.0 1 0 0 1 1 1 0 FANCI solenoid 4 DUF2357 PF09823.9 RUS80062.1 - 0.014 14.7 3.9 0.017 14.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF3313 PF11769.8 RUS80062.1 - 0.038 13.8 0.2 0.074 12.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) DUF883 PF05957.13 RUS80062.1 - 0.049 14.2 2.1 0.36 11.5 2.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.11 RUS80062.1 - 0.068 12.0 8.9 0.073 11.9 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Apolipoprotein PF01442.18 RUS80062.1 - 0.094 12.6 9.4 4.3 7.2 1.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5344 PF17279.2 RUS80062.1 - 0.14 12.7 6.1 0.64 10.6 6.1 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5344) Rota_NSP4 PF01452.16 RUS80062.1 - 0.15 11.7 0.8 0.17 11.5 0.8 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein YojJ PF10372.9 RUS80062.1 - 0.17 12.0 4.1 1.3 9.2 0.7 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Paralemmin PF03285.15 RUS80062.1 - 0.27 10.8 5.5 0.29 10.7 5.5 1.0 1 0 0 1 1 1 0 Paralemmin FapA PF03961.13 RUS80062.1 - 0.35 9.4 6.5 0.39 9.3 6.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YtxH PF12732.7 RUS80062.1 - 0.37 11.4 2.0 3 8.4 2.0 2.1 1 1 0 1 1 1 0 YtxH-like protein CLZ PF16526.5 RUS80062.1 - 0.48 10.8 10.7 0.59 10.5 1.9 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Halogen_Hydrol PF10112.9 RUS80062.1 - 0.51 10.3 4.3 0.29 11.1 0.4 1.8 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Laminin_II PF06009.12 RUS80062.1 - 0.56 10.2 6.0 3.3 7.7 0.7 2.1 1 1 1 2 2 2 0 Laminin Domain II CdvA PF18822.1 RUS80062.1 - 0.73 9.7 9.6 0.89 9.4 1.9 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain XhlA PF10779.9 RUS80062.1 - 0.74 10.1 4.4 15 5.9 4.2 2.3 1 1 0 1 1 1 0 Haemolysin XhlA FlxA PF14282.6 RUS80062.1 - 1.4 8.9 11.5 1.1 9.3 8.7 1.9 1 1 1 2 2 2 0 FlxA-like protein PCRF PF03462.18 RUS80062.1 - 1.5 8.6 5.9 1.9 8.3 5.9 1.1 1 0 0 1 1 1 0 PCRF domain NPV_P10 PF05531.12 RUS80062.1 - 1.7 9.2 5.4 24 5.5 5.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.6 RUS80062.1 - 1.7 9.3 8.8 1.2 9.8 1.4 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor HSCB_C PF07743.13 RUS80062.1 - 1.7 9.2 10.7 6.7 7.3 5.2 2.8 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Syntaxin-6_N PF09177.11 RUS80062.1 - 2.8 8.6 7.4 16 6.1 6.7 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DASH_Hsk3 PF08227.11 RUS80062.1 - 5 7.6 9.8 2.7 8.4 1.9 2.7 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like WD40 PF00400.32 RUS80063.1 - 0.00043 21.0 1.1 0.037 14.9 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat TIM PF00121.18 RUS80064.1 - 1.1e-90 303.2 0.0 1.3e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-H2C2_2 PF13465.6 RUS80065.1 - 2.4e-33 113.1 97.4 4.6e-08 33.1 2.2 13.6 13 1 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.26 RUS80065.1 - 1.3e-29 101.0 110.5 0.00045 20.5 2.3 15.0 15 0 0 15 15 15 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80065.1 - 2.6e-24 83.8 102.9 0.0063 17.3 1.6 15.0 15 0 0 15 15 15 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS80065.1 - 2.8e-05 24.3 35.8 0.036 14.4 0.3 9.9 11 0 0 11 11 10 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS80065.1 - 0.00023 20.8 2.9 0.00023 20.8 2.9 8.0 10 0 0 10 10 10 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS80065.1 - 0.001 19.0 6.9 0.0071 16.3 1.7 11.9 14 0 0 14 14 12 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS80065.1 - 0.0011 19.2 2.9 0.0011 19.2 2.9 6.1 4 1 3 7 7 6 3 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RUS80065.1 - 0.0074 16.0 53.4 0.016 14.9 0.3 9.5 9 0 0 9 9 9 4 zinc-finger C2H2-type zf-met PF12874.7 RUS80065.1 - 0.15 12.5 64.3 0.068 13.6 1.3 11.8 13 1 0 13 13 13 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 RUS80065.1 - 0.22 12.0 15.3 26 5.4 0.2 5.9 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain U71 PF17474.2 RUS80065.1 - 0.7 9.9 6.7 7.2 6.6 0.0 4.2 3 0 0 3 3 3 0 Tegument protein UL11 homolog DZR PF12773.7 RUS80065.1 - 5.3 7.2 45.3 0.13 12.4 3.9 7.8 4 3 2 6 6 6 0 Double zinc ribbon LBP_BPI_CETP PF01273.25 RUS80066.1 - 1.4e-06 28.0 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Lamprin PF06403.11 RUS80067.1 - 3.8e-13 49.6 56.9 0.021 14.8 6.5 5.4 1 1 4 5 5 5 5 Lamprin Chorion_1 PF01723.16 RUS80067.1 - 0.0088 16.0 93.9 1.8e+04 -67.5 93.9 6.3 1 1 0 1 1 1 0 Chorion protein LBP_BPI_CETP_C PF02886.17 RUS80068.1 - 6.8e-34 117.4 0.0 2.7e-32 112.1 0.0 2.0 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain SAMP PF05924.11 RUS80068.1 - 0.19 11.1 0.0 24 4.4 0.0 2.5 2 0 0 2 2 2 0 SAMP Motif 7TM_GPCR_Srx PF10328.9 RUS80069.1 - 7.9e-06 25.7 19.1 1.1e-05 25.2 19.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Orai-1 PF07856.12 RUS80069.1 - 1.4 8.5 8.0 0.5 10.0 0.1 2.4 1 1 0 2 2 2 0 Mediator of CRAC channel activity Cnd1_N PF12922.7 RUS80070.1 - 1.4e-33 116.1 0.0 2.6e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 RUS80071.1 - 0.00063 19.8 0.3 0.046 13.8 0.1 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RUS80071.1 - 0.00077 19.5 0.1 0.059 13.7 0.1 2.6 2 0 0 2 2 2 1 HEAT repeat Ribos_L4_asso_C PF14374.6 RUS80071.1 - 0.0099 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Cohesin_HEAT PF12765.7 RUS80071.1 - 0.068 13.5 1.4 0.095 13.0 0.2 1.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 RUS80072.1 - 3.4e-48 163.7 0.4 1.4e-47 161.8 0.3 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RUS80072.1 - 4.9e-05 22.1 3.1 0.0025 16.4 0.3 3.0 2 1 1 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.6 RUS80072.1 - 0.0002 21.7 0.1 0.016 15.6 0.0 4.0 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 RUS80072.1 - 0.0032 17.6 6.0 1.2 9.6 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat Cohesin_HEAT PF12765.7 RUS80072.1 - 0.013 15.8 0.2 0.24 11.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 RUS80072.1 - 0.045 13.0 3.5 0.17 11.1 0.6 2.8 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Thioredoxin_13 PF18401.1 RUS80072.1 - 0.051 13.5 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain BORCS7 PF16088.5 RUS80072.1 - 0.076 13.3 1.0 0.34 11.2 0.0 2.6 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 Vfa1 PF08432.10 RUS80072.1 - 3.6 7.9 9.9 0.18 12.2 3.2 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DSBA PF01323.20 RUS80073.1 - 1.6e-48 165.1 0.0 1.7e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CPSase_L_D3 PF02787.19 RUS80073.1 - 0.041 14.2 0.1 0.062 13.7 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain TFIIA PF03153.13 RUS80074.1 - 0.02 14.9 18.4 0.023 14.7 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 RUS80074.1 - 0.24 10.1 6.1 0.3 9.8 6.1 1.1 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 RUS80074.1 - 1.2 8.7 9.6 1.9 8.1 9.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal eIF-3_zeta PF05091.12 RUS80074.1 - 2.7 6.8 10.8 3.7 6.4 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Coilin_N PF15862.5 RUS80074.1 - 3.6 7.4 8.8 5.3 6.8 8.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus Zip PF02535.22 RUS80074.1 - 5.3 6.2 5.3 7.7 5.6 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PSS PF03034.15 RUS80075.1 - 2.1e-78 263.8 32.4 4.1e-63 213.7 16.9 2.3 1 1 1 2 2 2 2 Phosphatidyl serine synthase UPF0016 PF01169.19 RUS80075.1 - 0.091 13.1 3.1 13 6.2 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF3792 PF12670.7 RUS80075.1 - 0.099 12.8 0.1 0.099 12.8 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3792) 7tm_1 PF00001.21 RUS80076.1 - 0.025 13.9 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS80077.1 - 8.8e-22 77.7 0.2 1e-21 77.5 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Chloroa_b-bind PF00504.21 RUS80077.1 - 0.0041 17.7 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF420 PF04238.12 RUS80077.1 - 0.017 15.4 1.0 0.037 14.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF420) zf-H2C2_2 PF13465.6 RUS80078.1 - 8.2e-12 45.0 42.8 1.1e-06 28.8 4.5 6.2 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 RUS80078.1 - 5.8e-09 35.9 44.9 0.00015 22.1 6.2 5.5 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80078.1 - 4.8e-07 30.1 40.4 0.00056 20.5 5.0 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-trcl PF13451.6 RUS80078.1 - 0.0021 17.9 14.0 0.12 12.3 4.2 4.1 3 1 0 3 3 3 1 Probable zinc-ribbon domain zf-C2H2_jaz PF12171.8 RUS80078.1 - 0.0029 17.8 24.9 0.028 14.7 0.1 5.3 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS80078.1 - 0.0099 15.6 2.3 0.0099 15.6 2.3 4.1 4 0 0 4 4 4 1 zinc-finger C2H2-type C1_4 PF07975.12 RUS80078.1 - 0.011 16.0 0.5 0.011 16.0 0.5 4.0 1 1 3 4 4 3 0 TFIIH C1-like domain GAGA PF09237.11 RUS80078.1 - 0.016 15.0 1.8 0.016 15.0 1.8 2.9 2 1 0 3 3 3 0 GAGA factor zf-C2H2_6 PF13912.6 RUS80078.1 - 0.026 14.5 28.9 0.42 10.7 3.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger DUF5558 PF17713.1 RUS80078.1 - 0.045 14.1 0.8 0.079 13.3 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5558) zf-met PF12874.7 RUS80078.1 - 0.16 12.4 27.0 0.24 11.8 0.3 5.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS80078.1 - 0.17 12.0 17.3 5.1 7.3 0.4 4.0 2 1 1 3 3 3 0 Zinc ribbon domain DUF3268 PF11672.8 RUS80078.1 - 0.4 11.0 7.8 0.23 11.8 2.6 2.4 1 1 1 2 2 2 0 zinc-finger-containing domain DZR PF12773.7 RUS80078.1 - 0.55 10.3 17.3 43 4.2 7.9 3.1 1 1 1 2 2 2 0 Double zinc ribbon Zf_RING PF16744.5 RUS80078.1 - 1.4 9.1 10.5 2.2 8.5 1.8 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C2H2_3rep PF18868.1 RUS80078.1 - 1.5 9.5 13.6 0.56 10.9 1.0 3.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats TF_Zn_Ribbon PF08271.12 RUS80078.1 - 4 7.0 10.7 9.3 5.9 0.1 3.6 4 0 0 4 4 4 0 TFIIB zinc-binding DUF2256 PF10013.9 RUS80078.1 - 4.3 7.6 17.0 3.3 7.9 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 RUS80078.1 - 7.1 7.5 12.8 1.1e+02 3.7 6.0 2.9 1 1 1 2 2 2 0 zinc-ribbon family CpXC PF14353.6 RUS80078.1 - 8.9 6.4 9.7 6.7 6.8 0.2 3.2 2 1 1 3 3 3 0 CpXC protein Sprouty PF05210.13 RUS80078.1 - 9.8 6.6 12.5 1.5e+02 2.8 12.5 2.2 1 1 0 1 1 1 0 Sprouty protein (Spry) LRR_8 PF13855.6 RUS80079.1 - 3.9e-32 109.8 17.8 9.8e-08 31.6 0.2 5.2 2 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS80079.1 - 1.3e-30 104.9 24.4 1.2e-05 25.6 0.7 6.3 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS80079.1 - 9.9e-15 53.3 17.5 0.31 11.2 0.1 10.2 11 0 0 11 11 11 5 Leucine Rich repeat LRR_1 PF00560.33 RUS80079.1 - 4e-13 47.9 14.9 4.2 8.3 0.2 10.4 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS80079.1 - 1.9e-05 24.2 4.3 1.9e-05 24.2 4.3 3.2 1 1 1 3 3 3 1 Leucine-rich repeat CSTF_C PF14304.6 RUS80079.1 - 0.073 12.7 2.2 8.1 6.1 0.2 3.9 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal Laminin_II PF06009.12 RUS80079.1 - 2.9 7.9 6.8 0.28 11.2 1.3 2.2 3 0 0 3 3 3 0 Laminin Domain II LRR_4 PF12799.7 RUS80080.1 - 3.1e-05 24.2 0.2 0.019 15.4 0.1 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS80080.1 - 0.00026 20.7 0.1 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 Leucine rich repeat Thiolase_N PF00108.23 RUS80081.1 - 1.1e-16 61.0 0.7 3.4e-15 56.1 0.0 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS80081.1 - 3.3e-13 49.4 0.0 1.1e-10 41.2 0.0 2.8 2 1 0 2 2 2 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RUS80081.1 - 4.3e-05 23.2 0.5 0.002 17.7 0.1 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RUS80081.1 - 0.00034 20.4 1.7 0.0014 18.5 0.0 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 RUS80081.1 - 0.0025 17.8 0.0 7.7 6.6 0.0 3.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 RUS80081.1 - 0.0026 16.5 0.0 0.024 13.3 0.0 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) DSBA PF01323.20 RUS80081.1 - 0.0053 16.6 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Phosphatase PF15698.5 RUS80082.1 - 0.065 12.4 1.1 0.089 11.9 1.1 1.1 1 0 0 1 1 1 0 Phosphatase PQ-loop PF04193.14 RUS80083.1 - 5.5e-08 32.5 1.3 1.1e-06 28.3 0.5 2.7 2 0 0 2 2 2 1 PQ loop repeat DUF1211 PF06736.11 RUS80083.1 - 0.044 14.2 2.6 0.33 11.4 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) Ceramidase PF05875.12 RUS80083.1 - 0.11 11.9 6.5 0.071 12.5 5.0 1.3 1 1 0 1 1 1 0 Ceramidase CABIT PF12736.7 RUS80084.1 - 1.7e-15 57.0 0.0 6e-12 45.4 0.0 2.5 1 1 1 2 2 2 2 Cell-cycle sustaining, positive selection, RVT_1 PF00078.27 RUS80085.1 - 9.3e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS80085.1 - 2.2e-15 57.1 0.1 6.1e-14 52.4 0.1 2.3 1 1 0 1 1 1 1 RNase H RVT_1 PF00078.27 RUS80086.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 RUS80087.1 - 3.1e-15 55.8 0.0 5.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 RUS80087.1 - 0.02 15.0 6.5 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase IV CCDC106 PF15794.5 RUS80087.1 - 0.2 11.3 8.6 0.29 10.8 8.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DEAD PF00270.29 RUS80088.1 - 2.1e-39 135.1 0.1 3.4e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS80088.1 - 2.5e-31 108.3 0.2 7.8e-31 106.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS80088.1 - 7.6e-09 35.8 0.0 2.9e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RUS80088.1 - 0.013 15.8 0.1 0.038 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 RUS80088.1 - 0.036 13.9 0.1 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 Helicase MazG-like PF12643.7 RUS80088.1 - 0.14 12.4 0.5 0.41 10.9 0.5 1.7 1 0 0 1 1 1 0 MazG-like family Haspin_kinase PF12330.8 RUS80089.1 - 8.3e-10 38.1 0.0 8.3e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase PF00069.25 RUS80089.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain YqzE PF14038.6 RUS80089.1 - 5.6 7.0 7.0 5 7.2 0.1 2.6 2 0 0 2 2 2 0 YqzE-like protein Haspin_kinase PF12330.8 RUS80090.1 - 3.5e-50 171.0 0.1 4.2e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS80090.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RUS80090.1 - 0.024 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 RUS80090.1 - 0.044 13.1 0.0 0.073 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain AA_permease_2 PF13520.6 RUS80092.1 - 2.8e-61 207.6 33.4 3.9e-61 207.2 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS80092.1 - 8.2e-25 87.3 36.6 5.3e-24 84.6 36.6 2.0 1 1 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 RUS80093.1 - 2e-10 40.5 18.5 0.00021 21.5 0.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80093.1 - 7.2e-10 38.9 16.6 0.0035 18.0 0.8 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS80093.1 - 1.3e-08 34.9 12.3 6.2e-07 29.6 0.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 RUS80093.1 - 0.011 16.1 5.7 2.9 8.4 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RUS80093.1 - 0.03 14.6 4.2 0.13 12.6 4.2 2.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 RUS80093.1 - 0.13 12.5 8.9 0.23 11.8 2.9 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 RUS80093.1 - 0.17 11.7 1.5 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.21 RUS80093.1 - 0.44 10.8 4.3 0.78 10.0 0.7 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TM231 PF10149.9 RUS80094.1 - 9.7e-111 369.9 6.9 1.1e-110 369.7 6.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 COQ9 PF08511.11 RUS80095.1 - 1.8e-32 110.9 2.0 1.8e-32 110.9 2.0 2.0 2 0 0 2 2 2 1 COQ9 Kinetochor_Ybp2 PF08568.10 RUS80096.1 - 2.2e-25 89.2 4.9 1.2e-17 63.6 0.0 2.5 2 1 1 3 3 3 2 Uncharacterised protein family, YAP/Alf4/glomulin M-inducer_phosp PF06617.13 RUS80096.1 - 0.015 14.6 1.0 3.4 6.9 0.5 2.1 2 0 0 2 2 2 0 M-phase inducer phosphatase MARVEL PF01284.23 RUS80097.1 - 9.5e-15 54.9 17.6 1.4e-14 54.3 17.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.9 RUS80097.1 - 0.0051 16.4 3.4 0.0051 16.4 3.4 2.1 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family GWT1 PF06423.12 RUS80097.1 - 1.6 8.8 6.6 2.9 8.0 6.6 1.7 1 1 0 1 1 1 0 GWT1 DUF4491 PF14898.6 RUS80097.1 - 2.1 8.8 7.5 0.34 11.4 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) ETRAMP PF09716.10 RUS80097.1 - 2.8 8.1 7.3 0.2 11.7 0.3 2.5 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2070 PF09843.9 RUS80097.1 - 4.5 5.4 9.0 5.5 5.2 9.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SH2 PF00017.24 RUS80098.1 - 5.9e-15 55.1 0.0 2.1e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 SH2 domain SOCS_box PF07525.16 RUS80098.1 - 1e-10 41.8 0.1 1.8e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 SOCS box DUF1604 PF07713.13 RUS80099.1 - 1.2e-31 108.3 1.0 1.2e-31 108.3 1.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 RUS80099.1 - 1.2e-07 31.4 3.4 3.1e-07 30.2 2.2 2.3 2 0 0 2 2 2 1 G-patch domain Nucleocapsid-N PF11030.8 RUS80099.1 - 0.6 10.0 2.6 0.68 9.9 0.1 2.2 2 0 0 2 2 2 0 Nucleocapsid protein N Med10 PF09748.9 RUS80100.1 - 1.6e-35 121.7 2.7 1.8e-35 121.5 2.7 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CENP-F_leu_zip PF10473.9 RUS80100.1 - 0.026 14.5 2.2 0.1 12.6 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3958 PF13125.6 RUS80100.1 - 1 9.6 4.5 12 6.2 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) Na_H_Exchanger PF00999.21 RUS80101.1 - 1e-63 215.5 49.4 1.3e-63 215.1 49.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 RUS80101.1 - 2.2 8.2 6.6 11 5.9 0.9 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3464 PF11947.8 RUS80101.1 - 4.1 7.1 6.6 0.76 9.5 1.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Abhydrolase_3 PF07859.13 RUS80102.1 - 2.6e-49 168.0 0.1 3.1e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS80102.1 - 0.012 15.1 0.1 0.066 12.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 RUS80102.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 RUS80102.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 RUS80102.1 - 0.088 11.7 0.2 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family CbtB PF09489.10 RUS80102.1 - 0.13 12.4 0.8 25 5.1 0.0 2.8 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DER1 PF04511.15 RUS80103.1 - 2.8e-64 216.6 15.3 3.2e-64 216.4 15.3 1.0 1 0 0 1 1 1 1 Der1-like family HC2 PF07382.11 RUS80106.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Ig_3 PF13927.6 RUS80107.1 - 5e-51 171.2 14.7 4.6e-16 59.2 0.9 5.2 4 1 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RUS80107.1 - 6.7e-46 154.5 8.1 1.5e-10 41.2 0.1 5.2 4 1 1 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RUS80107.1 - 7.1e-41 138.2 2.6 5.8e-11 42.3 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 RUS80107.1 - 2.2e-33 114.3 9.0 8.7e-11 41.9 0.3 5.1 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 RUS80107.1 - 4.9e-25 87.8 6.6 1e-08 35.3 0.3 6.0 4 2 2 6 6 6 6 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS80107.1 - 5.3e-16 58.8 0.6 0.037 14.4 0.0 5.2 4 1 1 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS80107.1 - 1.4e-12 47.6 0.3 0.034 14.4 0.0 5.0 5 0 0 5 5 5 3 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS80107.1 - 1.4e-10 40.6 0.0 0.0014 18.2 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Izumo-Ig PF16706.5 RUS80107.1 - 3.5e-07 30.2 2.0 0.57 10.3 0.0 4.9 5 1 0 6 6 6 3 Izumo-like Immunoglobulin domain PKD_3 PF16820.5 RUS80107.1 - 0.00049 19.8 0.0 0.11 12.2 0.0 3.0 3 0 0 3 3 3 1 PKD-like domain C2-set_2 PF08205.12 RUS80107.1 - 0.0015 18.6 8.1 3.6 7.7 1.0 5.0 4 1 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 RUS80107.1 - 0.0018 18.0 1.1 5.7 6.8 0.0 4.0 4 2 0 4 4 4 1 Adenovirus E3 region protein CR1 DUF1918 PF08940.11 RUS80107.1 - 0.0025 17.4 1.0 5.3 6.7 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) Lep_receptor_Ig PF06328.11 RUS80107.1 - 0.0059 16.5 0.0 19 5.3 0.0 3.8 4 0 0 4 4 4 0 Ig-like C2-type domain C2-set PF05790.15 RUS80107.1 - 0.15 12.3 1.9 39 4.5 0.0 4.2 5 1 0 5 5 5 0 Immunoglobulin C2-set domain Ig_3 PF13927.6 RUS80108.1 - 2.3e-24 85.8 0.3 2.3e-11 44.1 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS80108.1 - 9.7e-23 80.1 0.1 6.9e-12 45.3 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS80108.1 - 4.2e-18 65.3 0.1 2.5e-09 37.2 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS80108.1 - 1.2e-15 57.5 0.7 2.5e-06 27.8 0.2 3.2 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS80108.1 - 1.2e-09 38.1 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS80108.1 - 3.2e-08 33.7 0.1 2.5e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS80108.1 - 0.00069 19.6 0.1 1.7 8.8 0.0 3.0 1 1 2 3 3 3 2 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 RUS80108.1 - 0.021 14.8 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 RUS80108.1 - 0.024 14.9 0.0 6.3 7.1 0.0 3.4 3 1 1 4 4 4 0 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 RUS80108.1 - 0.15 12.2 0.5 0.86 9.8 0.0 2.4 4 0 0 4 4 4 0 Immunoglobulin C2-set domain EphA2_TM PF14575.6 RUS80109.1 - 0.0036 18.1 1.7 0.011 16.6 0.2 2.6 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 RUS80109.1 - 0.033 14.2 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SCIMP PF15050.6 RUS80109.1 - 0.064 13.7 1.2 13 6.3 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein Orf78 PF06024.12 RUS80109.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.2 3 0 0 3 3 3 0 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 RUS80109.1 - 0.25 11.1 6.7 0.41 10.4 6.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Baculo_11_kDa PF06143.11 RUS80109.1 - 0.62 9.7 2.9 0.35 10.5 0.6 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Stevor PF17410.2 RUS80109.1 - 0.72 9.3 5.2 0.14 11.7 0.5 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF4834 PF16118.5 RUS80109.1 - 0.72 10.8 2.5 9.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SKG6 PF08693.10 RUS80109.1 - 8.4 5.9 8.7 16 5.0 8.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UCH PF00443.29 RUS80111.1 - 6.3e-48 163.5 0.0 8.8e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS80111.1 - 6.6e-08 32.5 0.0 2.8e-06 27.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_2 PF07719.17 RUS80111.1 - 0.026 14.6 0.0 0.086 13.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4482 PF14818.6 RUS80111.1 - 0.066 14.1 0.2 0.33 11.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) UIM PF02809.20 RUS80111.1 - 0.15 12.0 3.3 0.35 10.9 1.4 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif TPR_12 PF13424.6 RUS80111.1 - 0.2 12.0 1.9 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CLZ PF16526.5 RUS80111.1 - 0.75 10.2 7.7 12 6.3 0.2 3.6 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MerR-DNA-bind PF09278.11 RUS80111.1 - 7.5 7.2 7.3 35 5.0 0.9 3.1 3 0 0 3 3 3 0 MerR, DNA binding VP9 PF09625.10 RUS80112.1 - 9.5e-10 38.5 0.4 3.2 8.0 0.0 5.4 1 1 6 7 7 7 6 VP9 protein OS-D PF03392.13 RUS80112.1 - 1.1e-08 35.0 0.9 28 4.9 0.0 6.6 1 1 6 7 7 7 0 Insect pheromone-binding family, A10/OS-D Fungal_KA1 PF16797.5 RUS80112.1 - 1e-07 31.7 22.1 7.2 6.3 0.1 7.9 1 1 7 8 8 8 6 Fungal kinase associated-1 domain DUF1358 PF07096.11 RUS80112.1 - 4e-07 30.0 19.3 5.4 7.0 0.1 7.5 1 1 7 8 8 8 6 Protein of unknown function (DUF1358) DUF5409 PF17421.2 RUS80112.1 - 1e-06 29.3 8.4 11 6.8 0.0 6.0 1 1 6 7 7 7 2 Family of unknown function (DUF5409) Borrelia_orfD PF02999.14 RUS80112.1 - 1.2e-06 28.7 0.3 77 3.7 0.0 6.3 1 1 6 7 7 7 0 Borrelia orf-D family NTPase_1 PF03266.15 RUS80112.1 - 9.1e-06 25.7 0.0 1.5 8.7 0.0 3.8 1 1 3 4 4 4 4 NTPase DUF2122 PF09895.9 RUS80112.1 - 3.1e-05 24.3 0.0 2.4e+02 2.2 0.0 6.4 1 1 6 7 7 7 0 RecB-family nuclease (DUF2122) PIF3 PF05006.12 RUS80112.1 - 0.0033 17.5 1.1 89 3.1 0.1 4.6 1 1 5 6 6 6 0 Per os infectivity factor 3 SF3A3 PF16837.5 RUS80112.1 - 0.031 14.8 8.0 42 4.8 0.6 5.7 1 1 0 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PAS_11 PF14598.6 RUS80112.1 - 0.037 14.2 3.6 1.2e+02 2.8 0.1 4.8 1 1 5 6 6 6 0 PAS domain Varsurf_PPLC PF03490.13 RUS80112.1 - 0.24 11.4 5.4 4.7e+02 0.8 0.0 6.0 1 1 4 7 7 7 0 Variant-surface-glycoprotein phospholipase C ADH_N PF08240.12 RUS80113.1 - 9.1e-19 67.4 0.4 1.6e-18 66.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS80113.1 - 2.8e-06 27.3 0.1 5.2e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 RUS80114.1 - 1.5e-29 103.1 9.5 4.7e-29 101.4 5.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS80114.1 - 2.9e-07 30.1 5.9 4.7e-07 29.4 5.9 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 RUS80114.1 - 0.037 12.6 9.3 0.011 14.3 4.9 2.0 1 1 1 2 2 2 0 MFS/sugar transport protein Sugar_tr PF00083.24 RUS80114.1 - 0.33 9.8 15.5 3.4 6.4 15.5 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter DUF2574 PF10836.8 RUS80115.1 - 0.021 14.7 0.1 5.9 6.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) DNA_pol_P_Exo PF18049.1 RUS80115.1 - 0.069 12.6 0.3 26 4.1 0.1 3.6 1 1 3 4 4 4 0 DNA polymerase nu pseudo-exo Plasmodium_HRP PF05403.11 RUS80115.1 - 0.071 12.9 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Saccharop_dh_N PF04455.12 RUS80115.1 - 0.1 13.0 14.0 14 6.2 0.2 5.5 1 1 3 4 4 4 0 LOR/SDH bifunctional enzyme conserved region ABC_membrane_3 PF13748.6 RUS80115.1 - 0.15 11.3 10.5 14 4.8 0.3 4.0 1 1 2 3 3 3 0 ABC transporter transmembrane region Cro PF09048.10 RUS80116.1 - 0.0086 16.1 0.0 62 3.7 0.0 4.6 1 1 3 5 5 5 0 Cro BPL_LplA_LipB PF03099.19 RUS80116.1 - 0.4 10.6 9.9 2.2 8.2 0.8 3.3 1 1 2 3 3 3 0 Biotin/lipoate A/B protein ligase family SM-ATX PF14438.6 RUS80116.1 - 0.77 9.9 15.5 21 5.3 0.2 5.5 1 1 5 7 7 7 0 Ataxin 2 SM domain GW PF13457.6 RUS80116.1 - 1 10.0 17.8 0.77 10.4 3.7 3.1 1 1 1 2 2 2 0 GW (Gly-Tryp) dipeptide domain Babuvirus_MP PF07234.11 RUS80116.1 - 1.9 8.7 10.3 39 4.5 0.5 3.9 1 1 3 4 4 4 0 Movement and RNA silencing protein Lectin_C PF00059.21 RUS80117.1 - 2.6e-07 31.3 0.9 3.9e-07 30.8 0.9 1.3 1 0 0 1 1 1 1 Lectin C-type domain Lys PF00062.20 RUS80119.1 - 0.029 14.6 1.3 0.087 13.1 1.3 1.8 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family SR1P PF13790.6 RUS80119.1 - 0.39 10.9 3.1 0.44 10.7 0.3 2.5 2 0 0 2 2 2 0 SR1 protein WD40 PF00400.32 RUS80120.1 - 1e-11 45.2 11.2 0.0013 19.5 0.5 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS80120.1 - 3.8e-09 36.7 0.1 0.0016 18.7 0.1 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RUS80120.1 - 0.00034 19.1 0.0 0.0006 18.3 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF2053 PF09767.9 RUS80121.1 - 3.4e-70 235.3 6.1 4.7e-70 234.9 6.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) Glug PF07581.12 RUS80122.1 - 0.055 13.9 0.1 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 The GLUG motif Nop52 PF05997.12 RUS80123.1 - 4.3e-63 213.0 1.1 7.9e-63 212.1 1.1 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 RRN3 PF05327.11 RUS80123.1 - 0.053 12.1 3.2 0.13 10.8 3.2 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tetraspanin PF00335.20 RUS80124.1 - 3e-33 115.5 5.5 1.2e-29 103.7 0.1 2.1 1 1 1 2 2 2 2 Tetraspanin family TMEM51 PF15345.6 RUS80124.1 - 0.1 12.4 0.6 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 SUR7 PF06687.12 RUS80124.1 - 0.51 9.9 5.8 0.29 10.7 3.2 1.9 2 0 0 2 2 2 0 SUR7/PalI family TMEM154 PF15102.6 RUS80124.1 - 2.6 8.0 5.6 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family Scramblase PF03803.15 RUS80126.1 - 7.9e-69 231.3 0.0 9.7e-69 231.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase Glyco_transf_10 PF00852.19 RUS80127.1 - 2.5e-48 164.1 0.4 3.6e-48 163.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS80127.1 - 1.2e-13 51.5 0.0 3.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Tetraspanin PF00335.20 RUS80128.1 - 8.9e-17 61.6 2.2 1.1e-16 61.3 2.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3493 PF11998.8 RUS80128.1 - 0.054 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 LapA_dom PF06305.11 RUS80128.1 - 0.16 11.8 5.7 0.17 11.7 1.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 RUS80129.1 - 2.3e-17 63.0 21.5 2e-16 59.9 21.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 RUS80129.1 - 0.0055 15.3 22.6 0.13 10.8 7.0 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein EI24 PF07264.11 RUS80130.1 - 2.4e-07 31.2 17.5 2.4e-07 31.2 17.5 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SNF PF00209.18 RUS80131.1 - 2.4e-201 670.0 39.0 4.4e-201 669.1 39.0 1.4 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Glyco_transf_92 PF01697.27 RUS80133.1 - 5.5e-26 91.8 0.0 6.9e-25 88.2 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS80133.1 - 0.0028 18.2 0.1 0.0076 16.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 MACPF PF01823.19 RUS80138.1 - 4.1e-18 66.3 0.9 6.4e-18 65.6 0.9 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DC_STAMP PF07782.13 RUS80139.1 - 5.4e-52 176.4 0.4 5.4e-52 176.4 0.4 2.3 3 0 0 3 3 3 1 DC-STAMP-like protein 7tm_1 PF00001.21 RUS80139.1 - 0.018 14.4 0.0 1.6 8.0 0.0 2.5 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 RUS80139.1 - 0.079 13.3 0.0 1.1 9.6 0.0 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Prok-RING_1 PF14446.6 RUS80139.1 - 0.12 12.3 11.3 0.3 11.1 11.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 RUS80139.1 - 0.13 12.1 8.2 0.31 10.9 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 RUS80139.1 - 0.15 12.3 9.7 0.38 11.0 9.7 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_2 PF13639.6 RUS80139.1 - 0.3 11.4 10.0 0.76 10.2 10.0 1.7 1 0 0 1 1 1 0 Ring finger domain Tetraspanin PF00335.20 RUS80140.1 - 2.3e-36 125.7 21.5 1.3e-19 70.8 13.9 2.0 1 1 1 2 2 2 2 Tetraspanin family TauD PF02668.16 RUS80141.1 - 1e-38 133.7 0.0 1.4e-38 133.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PT PF04886.12 RUS80142.1 - 0.035 13.7 37.3 1.8e+04 -10.6 37.3 3.4 1 1 0 1 1 1 0 PT repeat Apt1 PF10351.9 RUS80142.1 - 0.081 11.8 10.1 0.081 11.8 10.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 RUS80142.1 - 0.39 9.4 14.7 0.48 9.1 14.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 RUS80142.1 - 0.46 10.3 8.4 0.58 9.9 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 RUS80142.1 - 0.82 8.4 11.0 0.96 8.1 11.0 1.2 1 0 0 1 1 1 0 Presenilin FAP PF07174.11 RUS80142.1 - 0.95 8.9 14.3 1.3 8.5 14.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Neur_chan_memb PF02932.16 RUS80142.1 - 7 6.6 8.3 11 6.0 8.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Patched PF02460.18 RUS80143.1 - 1.1e-85 288.4 19.9 1.4e-85 288.1 19.9 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 RUS80143.1 - 3.2e-37 127.7 1.6 3.2e-37 127.7 1.6 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 RUS80143.1 - 0.056 11.1 5.3 0.086 10.5 5.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.15 RUS80143.1 - 0.17 10.8 10.9 0.072 12.0 5.6 2.2 2 0 0 2 2 2 0 MMPL family Spt20 PF12090.8 RUS80144.1 - 0.2 11.2 17.3 0.4 10.3 17.3 1.4 1 0 0 1 1 1 0 Spt20 family Filamin PF00630.19 RUS80145.1 - 3.7e-72 239.7 3.2 3.3e-11 43.9 0.0 7.3 7 0 0 7 7 7 7 Filamin/ABP280 repeat PapC_N PF13954.6 RUS80145.1 - 6.1e-05 23.1 0.1 0.3 11.1 0.0 4.7 5 0 0 5 5 5 1 PapC N-terminal domain Y_Y_Y PF07495.13 RUS80145.1 - 0.00076 19.4 5.3 23 5.1 0.0 5.8 5 0 0 5 5 5 1 Y_Y_Y domain Big_3 PF07523.12 RUS80145.1 - 0.066 13.5 0.0 1.2e+02 3.1 0.0 4.5 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) YtkA PF13115.6 RUS80145.1 - 0.13 12.8 0.0 53 4.5 0.0 4.5 5 0 0 5 5 5 0 YtkA-like CH PF00307.31 RUS80146.1 - 3.8e-32 110.7 0.5 8.8e-21 74.1 0.0 3.1 2 1 1 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS80146.1 - 0.00014 21.6 0.0 0.079 12.8 0.0 2.8 2 1 0 2 2 2 2 CAMSAP CH domain APG6_N PF17675.1 RUS80147.1 - 0.0047 17.4 5.2 0.0047 17.4 5.2 2.9 2 1 1 3 3 3 1 Apg6 coiled-coil region Globin PF00042.22 RUS80147.1 - 0.015 15.8 2.1 0.042 14.4 1.2 2.1 1 1 1 2 2 2 0 Globin Atg14 PF10186.9 RUS80147.1 - 0.59 9.2 20.4 0.015 14.4 5.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 RUS80147.1 - 2.6 8.2 24.4 2.1 8.6 4.4 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 RUS80148.1 - 1.4e-26 93.5 0.0 1.5e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80148.1 - 8.4e-13 48.2 0.0 9.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80148.1 - 1.3e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like FRQ PF09421.10 RUS80148.1 - 0.0095 14.0 0.1 0.012 13.6 0.1 1.1 1 0 0 1 1 1 1 Frequency clock protein Haspin_kinase PF12330.8 RUS80148.1 - 0.012 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RUS80148.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ig_3 PF13927.6 RUS80149.1 - 1.1e-07 32.3 0.3 0.00023 21.7 0.0 3.7 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 RUS80149.1 - 2.1e-06 27.7 0.0 0.0027 17.7 0.0 3.2 3 1 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 RUS80149.1 - 0.00041 20.5 1.0 0.41 10.8 0.0 3.0 3 1 0 3 3 3 2 Immunoglobulin V-set domain SKG6 PF08693.10 RUS80149.1 - 0.0012 18.2 2.7 0.0026 17.1 2.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 RUS80149.1 - 0.0037 16.2 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Amnionless Ig_2 PF13895.6 RUS80149.1 - 0.006 16.9 0.1 0.42 11.0 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR2 PF02439.15 RUS80149.1 - 0.015 15.1 0.2 0.015 15.1 0.2 1.9 2 0 0 2 2 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 RUS80149.1 - 0.023 14.6 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Glycophorin_A PF01102.18 RUS80149.1 - 0.041 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 RUS80149.1 - 0.046 14.6 0.0 0.14 13.0 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 RUS80149.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5385) OAD_gamma PF04277.13 RUS80149.1 - 0.12 13.0 0.0 0.57 10.8 0.0 2.2 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Stevor PF17410.2 RUS80149.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 RUS80149.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) PTP_tm PF18861.1 RUS80149.1 - 0.59 10.1 2.0 0.7 9.9 0.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4834 PF16118.5 RUS80149.1 - 5.2 8.1 4.6 11 7.1 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) LST1 PF05083.13 RUS80149.1 - 9.6 6.6 6.8 1.1 9.6 0.3 2.9 4 1 0 4 4 2 0 LST-1 protein DHHC PF01529.20 RUS80150.1 - 7.5e-21 74.6 11.2 7.5e-21 74.6 11.2 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase PRA1 PF03208.19 RUS80150.1 - 0.03 13.9 0.4 0.03 13.9 0.4 3.5 3 1 0 3 3 3 0 PRA1 family protein zf-C4 PF00105.18 RUS80151.1 - 8.6e-24 83.8 15.0 1.7e-23 82.9 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3136 PF11334.8 RUS80152.1 - 0.002 17.9 14.4 9.7 6.1 0.1 5.2 1 1 4 5 5 5 5 Protein of unknown function (DUF3136) PKHD_C PF18331.1 RUS80152.1 - 0.028 14.5 7.5 51 4.0 0.1 5.6 1 1 5 6 6 6 0 PKHD-type hydroxylase C-terminal domain Hormone_recep PF00104.30 RUS80153.1 - 1.9e-10 40.7 1.0 3.6e-10 39.8 1.0 1.4 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF4157 PF13699.6 RUS80154.1 - 0.063 13.5 7.0 15 5.9 0.3 5.0 2 1 4 6 6 6 0 Domain of unknown function (DUF4157) SAPS PF04499.15 RUS80154.1 - 2.6 6.7 15.8 4.2 6.1 15.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S8 PF00082.22 RUS80156.1 - 1.3e-38 133.0 6.1 1.9e-38 132.5 6.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RUS80156.1 - 4.1e-13 49.2 0.1 1.3e-12 47.5 0.1 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 RUS80156.1 - 0.0018 18.8 0.1 0.0049 17.4 0.1 1.7 1 0 0 1 1 1 1 N-terminal of Subtilase family LemA PF04011.12 RUS80157.1 - 8.2e-07 29.0 12.2 0.0092 15.8 1.3 3.4 1 1 4 5 5 5 5 LemA family NID PF07292.13 RUS80157.1 - 0.0017 19.0 13.0 30 5.4 0.1 5.7 1 1 5 6 6 6 0 Nmi/IFP 35 domain (NID) YcaO_C PF18381.1 RUS80157.1 - 0.17 11.8 1.8 35 4.3 0.1 3.6 1 1 4 5 5 5 0 YcaO cyclodehydratase C-terminal domain Gemini_AL1 PF00799.20 RUS80157.1 - 0.22 11.9 7.7 12 6.3 2.7 3.2 2 1 0 2 2 2 0 Geminivirus Rep catalytic domain PilM PF07419.12 RUS80157.1 - 0.43 10.8 6.6 17 5.6 0.2 3.1 1 1 2 3 3 3 0 PilM DUF2476 PF10630.9 RUS80157.1 - 0.46 10.6 1.1 12 5.9 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2476) DUF3791 PF12668.7 RUS80157.1 - 1.3 9.1 18.4 36 4.5 0.1 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF3791) EZH2_N PF18601.1 RUS80157.1 - 1.6 9.1 11.3 9.9 6.6 0.2 4.5 1 1 3 5 5 5 0 EZH2 N-terminal domain Uteroglobin PF01099.17 RUS80157.1 - 1.7 9.0 10.2 66 3.9 0.2 4.5 1 1 5 6 6 6 0 Uteroglobin family BBP1_N PF15271.6 RUS80157.1 - 1.8 9.3 5.7 9.9 6.9 0.8 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein PTPS_related PF10131.9 RUS80157.1 - 8.4 4.6 6.0 15 3.8 0.4 2.4 1 1 2 3 3 3 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein PRA1 PF03208.19 RUS80158.1 - 2.6e-35 121.1 0.1 3.5e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein Branch PF02485.21 RUS80159.1 - 4.5e-37 127.9 0.1 9.7e-18 64.6 0.0 2.6 2 0 0 2 2 2 2 Core-2/I-Branching enzyme TMEM214 PF10151.9 RUS80159.1 - 0.071 11.6 0.4 0.098 11.1 0.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Vinculin PF01044.19 RUS80160.1 - 5.4e-10 38.2 2.0 6e-10 38.1 2.0 1.0 1 0 0 1 1 1 1 Vinculin family DNA_pol_phi PF04931.13 RUS80161.1 - 0.03 12.5 33.0 0.061 11.4 33.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi RP-C_C PF11800.8 RUS80161.1 - 0.4 10.7 20.7 0.96 9.5 7.6 3.8 2 0 0 2 2 2 0 Replication protein C C-terminal region TFIIA PF03153.13 RUS80161.1 - 7.2 6.5 52.5 0.26 11.2 13.7 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RUS80162.1 - 0.31 9.2 29.3 0.36 9.0 29.3 1.0 1 0 0 1 1 1 0 Nop14-like family zf-H2C2_2 PF13465.6 RUS80164.1 - 7.5e-36 121.0 44.5 5.3e-09 36.1 1.4 7.6 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS80164.1 - 4.4e-26 89.9 62.8 6.3e-06 26.4 0.5 7.4 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80164.1 - 2.7e-18 65.1 56.3 0.00074 20.2 0.8 7.9 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS80164.1 - 4.9e-17 61.5 46.1 0.00017 21.5 0.7 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS80164.1 - 7.3e-13 48.4 18.1 0.001 19.3 0.1 7.2 5 3 2 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS80164.1 - 9e-12 45.0 28.2 0.0044 17.4 0.2 7.0 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS80164.1 - 0.0014 18.9 21.4 0.082 13.2 0.5 3.8 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RUS80164.1 - 0.0047 16.7 33.9 0.13 12.0 0.4 6.8 7 0 0 7 7 7 3 zinc-finger C2H2-type BolA PF01722.18 RUS80164.1 - 0.028 14.7 0.7 35 4.8 0.3 3.8 2 1 2 4 4 4 0 BolA-like protein zf-CHCC PF10276.9 RUS80164.1 - 0.043 13.9 10.9 9.2 6.4 0.1 5.6 5 0 0 5 5 5 0 Zinc-finger domain zf-C2HC_2 PF13913.6 RUS80164.1 - 0.056 13.4 25.7 5.8 6.9 0.4 7.2 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RUS80164.1 - 0.77 9.9 21.2 3.1 8.0 0.6 4.9 3 1 1 4 4 4 0 Zinc ribbon domain FYVE PF01363.21 RUS80164.1 - 2 8.6 32.1 38 4.5 13.9 4.3 2 2 1 3 3 3 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 RUS80164.1 - 5.6 7.8 22.3 18 6.2 1.0 4.3 2 2 1 4 4 4 0 zinc-ribbon family TILa PF12714.7 RUS80165.1 - 9.9 6.2 8.6 2.5 8.1 1.6 2.4 2 0 0 2 2 2 0 TILa domain TIR_2 PF13676.6 RUS80167.1 - 0.077 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 TIR domain NHL PF01436.21 RUS80170.1 - 4.7e-14 51.6 5.5 0.00099 19.0 0.1 4.6 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 RUS80170.1 - 0.00013 21.7 0.0 0.0035 16.9 0.0 2.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF2635 PF10948.8 RUS80170.1 - 0.18 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Pkinase PF00069.25 RUS80172.1 - 1.4e-48 165.6 0.0 2.7e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80172.1 - 2.5e-25 89.3 0.0 1.5e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 RUS80172.1 - 1.6e-05 24.7 0.1 0.0074 15.9 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain Kinase-like PF14531.6 RUS80172.1 - 1.6e-05 24.4 0.0 5.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RUS80172.1 - 0.0012 18.8 0.0 0.0053 16.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family PQQ PF01011.21 RUS80172.1 - 0.0034 17.2 0.0 7.5 6.7 0.0 3.8 4 0 0 4 4 4 2 PQQ enzyme repeat Kdo PF06293.14 RUS80172.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Vps16_C PF04840.12 RUS80173.1 - 0.07 12.2 0.5 0.13 11.3 0.5 1.5 1 0 0 1 1 1 0 Vps16, C-terminal region zf-H2C2_2 PF13465.6 RUS80174.1 - 8.6e-31 105.0 85.3 1.3e-07 31.7 1.4 10.5 11 0 0 11 11 10 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS80174.1 - 1.3e-27 94.0 68.3 0.00029 21.4 0.2 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS80174.1 - 1.7e-26 91.2 76.3 6.8e-06 26.3 0.5 10.0 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS80174.1 - 6.2e-09 35.6 48.2 0.036 14.1 0.1 9.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 RUS80174.1 - 3.7e-08 33.5 39.9 0.0089 16.4 0.1 8.6 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS80174.1 - 3.1e-05 24.1 7.8 0.012 15.9 0.1 9.1 9 1 1 10 10 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS80174.1 - 0.00034 20.3 1.2 0.035 13.9 0.0 7.8 9 0 0 9 9 9 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RUS80174.1 - 0.0069 16.3 0.3 0.0069 16.3 0.3 8.1 8 1 0 8 8 8 2 zinc-finger of a C2HC-type Ta0938 PF11494.8 RUS80174.1 - 0.032 14.5 0.6 0.032 14.5 0.6 4.3 2 1 2 4 4 4 0 Ta0938 BolA PF01722.18 RUS80174.1 - 0.039 14.2 3.9 20 5.6 0.1 3.9 1 1 3 4 4 4 0 BolA-like protein DUF3268 PF11672.8 RUS80174.1 - 0.043 14.2 0.7 0.043 14.2 0.7 4.1 4 1 0 5 5 5 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 RUS80174.1 - 0.31 11.8 30.0 1.7 9.4 1.1 5.0 4 1 1 5 5 5 0 zinc-ribbon family zf-Di19 PF05605.12 RUS80174.1 - 1.7 9.0 41.5 10 6.5 4.7 6.2 2 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RUS80174.1 - 3.8 7.2 29.1 4.9 6.8 0.1 7.7 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Ank PF00023.30 RUS80175.1 - 0.0017 18.7 0.2 0.14 12.7 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RUS80175.1 - 0.002 18.4 0.3 0.019 15.3 0.1 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS80175.1 - 0.0032 18.0 0.1 0.01 16.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS80175.1 - 0.0042 17.5 0.1 1.9 9.3 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 RUS80175.1 - 0.005 17.4 0.4 0.28 11.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS80175.1 - 0.022 15.1 3.9 0.022 15.1 3.9 2.6 3 1 0 3 3 3 0 SOCS box Ank_2 PF12796.7 RUS80176.1 - 4.3e-26 91.3 0.0 1.4e-10 41.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS80176.1 - 1.2e-24 86.3 0.0 6.6e-07 29.8 0.0 7.2 5 1 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS80176.1 - 3.6e-20 71.8 6.3 1.4e-09 38.0 0.0 6.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS80176.1 - 4.3e-17 61.7 7.0 1e-05 25.7 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 RUS80176.1 - 2.1e-16 58.4 0.0 0.00027 21.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat RCC1 PF00415.18 RUS80177.1 - 4.5e-42 142.4 17.3 7.7e-10 39.3 0.0 7.2 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS80177.1 - 8.3e-34 114.7 33.1 8.4e-08 31.8 1.8 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 RUS80177.1 - 2.1e-06 27.6 0.0 0.13 11.9 0.0 3.6 3 1 1 4 4 4 2 TUP1-like enhancer of split PQQ_3 PF13570.6 RUS80177.1 - 2.7 8.6 4.1 53 4.5 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Macoilin PF09726.9 RUS80177.1 - 9.2 4.7 8.1 14 4.1 8.1 1.2 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 RUS80178.1 - 0.00021 21.6 8.7 0.00043 20.6 8.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain SDA1 PF05285.12 RUS80178.1 - 0.00074 19.0 7.2 0.0008 18.9 7.2 1.1 1 0 0 1 1 1 1 SDA1 FAM176 PF14851.6 RUS80178.1 - 0.00076 19.2 3.2 0.0014 18.3 3.2 1.6 1 0 0 1 1 1 1 FAM176 family RNA_pol_3_Rpc31 PF11705.8 RUS80178.1 - 0.00078 19.8 10.1 0.00097 19.5 10.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4366 PF14283.6 RUS80178.1 - 0.0012 18.9 1.3 0.0021 18.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4746 PF15928.5 RUS80178.1 - 0.0017 17.8 6.5 0.0022 17.5 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Sigma70_ner PF04546.13 RUS80178.1 - 0.0021 18.0 5.3 0.0025 17.7 5.3 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Orf78 PF06024.12 RUS80178.1 - 0.0034 17.7 0.1 0.0064 16.8 0.1 1.4 1 0 0 1 1 1 1 Orf78 (ac78) DUF5305 PF17231.2 RUS80178.1 - 0.0047 16.4 0.1 0.0061 16.0 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) CbtA PF09490.10 RUS80178.1 - 0.0063 16.3 3.7 0.011 15.5 3.7 1.3 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) DcuA_DcuB PF03605.14 RUS80178.1 - 0.0063 15.4 0.3 0.0085 15.0 0.3 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter Afi1 PF07792.12 RUS80178.1 - 0.0078 16.7 1.6 0.012 16.1 1.6 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DARPP-32 PF05395.12 RUS80178.1 - 0.0088 16.3 8.6 0.014 15.6 8.6 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 Nop14 PF04147.12 RUS80178.1 - 0.01 14.1 11.2 0.011 14.0 11.2 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 RUS80178.1 - 0.011 15.1 13.3 0.015 14.6 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 RUS80178.1 - 0.011 15.7 4.1 0.016 15.2 4.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 RUS80178.1 - 0.015 14.9 11.2 0.018 14.6 11.2 1.2 1 0 0 1 1 1 0 PPP4R2 MAM33 PF02330.16 RUS80178.1 - 0.019 14.9 8.0 0.027 14.4 8.0 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein BSP_II PF05432.11 RUS80178.1 - 0.02 14.6 12.9 0.028 14.1 12.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Connexin PF00029.19 RUS80178.1 - 0.02 14.7 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Connexin Shisa PF13908.6 RUS80178.1 - 0.025 14.8 0.3 0.058 13.6 0.0 1.6 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator TFIIF_alpha PF05793.12 RUS80178.1 - 0.028 13.0 9.9 0.032 12.8 9.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATG22 PF11700.8 RUS80178.1 - 0.031 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Trypan_PARP PF05887.11 RUS80178.1 - 0.031 14.2 10.2 0.05 13.6 10.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EIIBC-GUT_N PF03612.14 RUS80178.1 - 0.033 13.9 0.9 0.051 13.3 0.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CrgA PF06781.12 RUS80178.1 - 0.035 14.2 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Cell division protein CrgA GCIP PF13324.6 RUS80178.1 - 0.036 13.7 6.6 0.047 13.3 6.6 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Med17 PF10156.9 RUS80178.1 - 0.037 12.7 1.9 0.038 12.7 1.9 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Astro_capsid_p PF12226.8 RUS80178.1 - 0.038 13.1 15.0 0.05 12.7 15.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2207 PF09972.9 RUS80178.1 - 0.039 12.7 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RXT2_N PF08595.11 RUS80178.1 - 0.044 13.8 7.6 0.071 13.1 7.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Mpp10 PF04006.12 RUS80178.1 - 0.047 12.1 12.5 0.061 11.8 12.5 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 RUS80178.1 - 0.055 12.4 1.6 0.059 12.3 1.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF719 PF05334.13 RUS80178.1 - 0.058 13.6 4.1 0.086 13.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) SURF2 PF05477.11 RUS80178.1 - 0.061 13.0 3.5 0.07 12.8 3.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Prothymosin PF03247.14 RUS80178.1 - 0.063 13.7 25.5 0.11 13.0 25.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Serinc PF03348.15 RUS80178.1 - 0.083 11.8 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 RUS80178.1 - 0.089 12.0 2.1 0.11 11.7 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.8 RUS80178.1 - 0.096 11.6 5.0 0.11 11.4 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleoside_tran PF01733.18 RUS80178.1 - 0.097 12.0 0.5 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter MscS_TM PF12794.7 RUS80178.1 - 0.11 11.3 3.3 0.16 10.8 3.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SseC PF04888.12 RUS80178.1 - 0.11 12.0 3.5 0.16 11.5 3.5 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RPA43_OB PF17875.1 RUS80178.1 - 0.12 13.0 4.4 0.08 13.6 2.8 1.6 2 0 0 2 2 1 0 RPA43 OB domain in RNA Pol I TRAP_alpha PF03896.16 RUS80178.1 - 0.12 11.5 6.4 0.17 11.0 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.12 RUS80178.1 - 0.14 11.9 5.8 0.18 11.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 RUS80178.1 - 0.16 9.7 4.3 0.2 9.4 4.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LRRC37AB_C PF14914.6 RUS80178.1 - 0.17 11.8 0.6 0.25 11.3 0.6 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Gaa1 PF04114.14 RUS80178.1 - 0.2 10.6 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DNA_pol_phi PF04931.13 RUS80178.1 - 0.2 9.7 20.2 0.26 9.4 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS80178.1 - 0.26 9.8 5.3 0.31 9.5 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 RUS80178.1 - 0.27 11.0 6.2 0.38 10.5 6.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BORG_CEP PF14957.6 RUS80178.1 - 0.47 11.6 4.2 0.67 11.1 4.2 1.3 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.14 RUS80178.1 - 0.54 8.5 13.0 0.68 8.2 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 RUS80178.1 - 0.57 8.0 2.7 0.7 7.7 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sporozoite_P67 PF05642.11 RUS80178.1 - 0.74 7.8 8.2 0.93 7.5 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.13 RUS80178.1 - 0.77 8.7 15.6 0.99 8.3 15.6 1.1 1 0 0 1 1 1 0 Paf1 PBP_sp32 PF07222.12 RUS80178.1 - 1.3 8.4 9.5 1.7 8.1 9.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nucleo_P87 PF07267.11 RUS80178.1 - 1.5 7.6 3.9 1.6 7.5 3.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3377 PF11857.8 RUS80178.1 - 1.8 8.5 8.1 2 8.4 6.8 1.8 2 1 0 2 2 1 0 Domain of unknown function (DUF3377) Radial_spoke PF04712.12 RUS80178.1 - 2.5 7.0 15.3 3.5 6.5 15.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CD99L2 PF12301.8 RUS80178.1 - 2.5 8.3 7.2 5.8 7.2 6.9 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 NPR3 PF03666.13 RUS80178.1 - 2.6 6.7 5.3 3.2 6.5 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3169 PF11368.8 RUS80178.1 - 3 7.3 5.1 5.2 6.5 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) CobT PF06213.12 RUS80178.1 - 3.2 7.1 16.8 4.9 6.4 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TLP-20 PF06088.11 RUS80178.1 - 3.4 7.5 6.6 5.4 6.9 6.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop53 PF07767.11 RUS80178.1 - 3.4 7.0 18.5 0.77 9.1 15.0 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF2428 PF10350.9 RUS80178.1 - 4 6.6 6.0 5.9 6.1 6.0 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF3464 PF11947.8 RUS80178.1 - 9.4 6.0 6.5 15 5.3 6.5 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Hormone_recep PF00104.30 RUS80180.1 - 4.2e-39 134.3 0.1 4.2e-39 134.3 0.1 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS80180.1 - 6.8e-30 103.3 16.3 6.8e-30 103.3 16.3 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) GEMIN8 PF15348.6 RUS80180.1 - 0.053 13.8 7.4 0.096 13.0 7.4 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Macoilin PF09726.9 RUS80180.1 - 0.37 9.3 14.5 0.53 8.8 14.5 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 RUS80180.1 - 1.8 8.4 17.7 30 4.4 19.7 1.8 2 0 0 2 2 2 0 SPX domain SelP_N PF04592.14 RUS80180.1 - 2.5 7.4 23.0 0.16 11.3 17.7 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.22 RUS80180.1 - 2.6 7.2 10.9 3.7 6.7 10.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 RUS80180.1 - 2.9 6.6 5.5 3.9 6.1 5.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 RUS80180.1 - 4.9 7.1 7.7 7.5 6.5 7.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) KxDL PF10241.9 RUS80182.1 - 2.1e-24 85.6 0.7 3.3e-24 85.0 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein PhaP_Bmeg PF09602.10 RUS80182.1 - 0.014 15.3 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Copine PF07002.16 RUS80183.1 - 1.1e-82 276.8 0.0 1.5e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS80183.1 - 2.4e-28 98.4 0.0 1e-12 48.2 0.0 2.2 2 0 0 2 2 2 2 C2 domain VWA PF00092.28 RUS80183.1 - 0.0023 18.2 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 RUS80183.1 - 0.0026 17.9 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus CRAL_TRIO PF00650.20 RUS80184.1 - 5.7e-26 91.1 0.0 9.3e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RUS80184.1 - 0.00029 20.9 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain I-set PF07679.16 RUS80185.1 - 1.6e-21 76.2 0.6 7.3e-13 48.4 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS80185.1 - 8.9e-20 71.1 21.1 8.2e-13 48.8 0.2 4.5 4 0 0 4 4 3 2 Immunoglobulin domain ig PF00047.25 RUS80185.1 - 1.6e-12 47.4 14.8 3.5e-08 33.5 0.1 4.2 3 1 0 3 3 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS80185.1 - 6.5e-12 45.6 3.2 1.9e-08 34.5 0.1 3.9 5 0 0 5 5 4 2 Immunoglobulin domain V-set PF07686.17 RUS80185.1 - 2.4e-09 37.3 4.4 0.045 13.9 0.2 4.8 2 2 1 3 3 3 3 Immunoglobulin V-set domain V-set_CD47 PF08204.11 RUS80185.1 - 0.00024 21.1 2.0 0.017 15.1 0.5 3.1 1 1 1 2 2 2 1 CD47 immunoglobulin-like domain Ig_6 PF18452.1 RUS80185.1 - 0.004 16.7 0.0 2.8 7.6 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain SOG2 PF10428.9 RUS80185.1 - 0.023 13.9 14.2 0.032 13.4 14.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF678 PF05077.12 RUS80185.1 - 0.098 12.8 12.2 0.075 13.2 8.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF678) Macoilin PF09726.9 RUS80185.1 - 1.7 7.1 5.9 2.2 6.7 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Toxin_TOLIP PF00087.21 RUS80185.1 - 2 8.7 33.8 0.037 14.3 9.6 2.8 2 0 0 2 2 2 0 Snake toxin and toxin-like protein DUF3498 PF12004.8 RUS80185.1 - 6.1 5.9 15.1 9.5 5.3 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF908 PF06012.12 RUS80185.1 - 6.5 6.1 13.7 9.6 5.5 13.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Tetraspanin PF00335.20 RUS80186.1 - 1.3e-10 41.3 13.0 3.8e-09 36.6 2.4 2.0 1 1 1 2 2 2 2 Tetraspanin family TMEM119 PF15724.5 RUS80186.1 - 0.003 17.7 0.8 0.0037 17.4 0.8 1.1 1 0 0 1 1 1 1 TMEM119 family Tetraspanin PF00335.20 RUS80187.1 - 2.4e-49 168.1 15.7 3.2e-49 167.7 15.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 RUS80187.1 - 0.67 10.3 7.9 0.38 11.1 2.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) COMP PF11598.8 RUS80188.1 - 0.0048 17.3 12.2 0.0079 16.7 2.9 2.9 1 1 2 3 3 3 2 Cartilage oligomeric matrix protein APG6_N PF17675.1 RUS80188.1 - 0.01 16.3 2.5 0.014 15.9 2.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region PLU-1 PF08429.11 RUS80188.1 - 0.052 12.7 1.2 0.13 11.5 1.3 1.4 1 1 1 2 2 2 0 PLU-1-like protein CENP-Q PF13094.6 RUS80188.1 - 0.052 13.7 4.0 0.064 13.5 4.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Utp12 PF04003.12 RUS80188.1 - 0.061 13.6 8.8 0.1 12.9 8.8 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family SKA2 PF16740.5 RUS80188.1 - 0.09 12.6 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 RUS80188.1 - 0.1 10.5 0.5 0.12 10.3 0.5 1.2 1 0 0 1 1 1 0 Prominin HAUS-augmin3 PF14932.6 RUS80188.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Med21 PF11221.8 RUS80188.1 - 0.11 12.8 3.4 0.37 11.0 2.6 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Med30 PF11315.8 RUS80188.1 - 0.18 12.0 1.3 0.84 9.8 0.9 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 Amnionless PF14828.6 RUS80188.1 - 0.2 10.4 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF948 PF06103.11 RUS80188.1 - 0.26 11.5 0.0 0.46 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ran-binding PF05508.11 RUS80188.1 - 0.28 10.1 0.6 0.37 9.7 0.6 1.1 1 0 0 1 1 1 0 RanGTP-binding protein FlgN PF05130.12 RUS80188.1 - 0.31 11.5 4.5 3.1 8.3 5.8 1.5 1 1 0 1 1 1 0 FlgN protein Rx_N PF18052.1 RUS80188.1 - 0.61 10.4 4.1 1.2 9.5 3.3 1.7 1 1 0 1 1 1 0 Rx N-terminal domain DUF4763 PF15960.5 RUS80188.1 - 0.83 8.9 5.4 1.1 8.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) HisKA_3 PF07730.13 RUS80188.1 - 1.1 9.8 14.5 3.5e+02 1.8 14.5 2.8 1 1 0 1 1 1 0 Histidine kinase IKKbetaNEMObind PF12179.8 RUS80188.1 - 1.5 9.0 7.9 7 6.8 1.0 2.8 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Syntaxin-6_N PF09177.11 RUS80188.1 - 2 9.0 4.4 7.7 7.1 4.4 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Complex1_LYR_2 PF13233.6 RUS80188.1 - 2.9 8.7 12.4 3.8e+03 -1.3 12.4 3.1 1 1 0 1 1 1 0 Complex1_LYR-like COMM_domain PF07258.14 RUS80188.1 - 4.4 7.5 7.1 40 4.4 0.3 3.2 1 1 2 3 3 3 0 COMM domain Helo_like_N PF17111.5 RUS80188.1 - 4.8 6.5 8.7 21 4.4 8.7 1.8 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins ALIX_LYPXL_bnd PF13949.6 RUS80188.1 - 5.5 6.2 6.4 11 5.2 6.4 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Cohesin_load PF10345.9 RUS80189.1 - 1.2e-106 357.5 15.0 1.4e-106 357.3 15.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 RUS80189.1 - 1.1e-10 41.6 0.6 0.073 13.4 0.0 6.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS80189.1 - 1e-08 35.0 8.3 0.006 16.0 0.0 3.8 2 1 1 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 RUS80189.1 - 9.6e-07 28.5 8.5 5.1 7.6 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS80189.1 - 0.00039 20.3 5.8 27 5.2 0.2 6.8 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS80189.1 - 0.039 13.8 10.4 11 6.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 RUS80189.1 - 0.45 10.2 1.8 4.6 6.9 0.0 3.0 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 RUS80189.1 - 1.2 10.2 3.7 80 4.5 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Utp12 PF04003.12 RUS80189.1 - 2.8 8.3 8.9 9 6.7 0.2 4.1 4 1 1 5 5 5 0 Dip2/Utp12 Family Sulfotransfer_3 PF13469.6 RUS80190.1 - 4.5e-09 37.0 1.4 0.0001 22.8 0.4 3.2 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS80190.1 - 5.8e-05 22.7 0.1 0.0065 16.0 0.1 2.7 1 1 0 1 1 1 1 Sulfotransferase domain zf-C2H2 PF00096.26 RUS80191.1 - 1.1e-29 101.1 39.1 1.2e-06 28.6 0.9 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS80191.1 - 1.1e-27 95.2 42.8 1e-07 32.0 2.1 6.9 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS80191.1 - 8.1e-12 45.1 15.6 0.011 16.0 0.4 5.4 6 0 0 6 6 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RUS80191.1 - 1.5e-09 37.8 34.1 0.0017 19.1 0.8 7.0 7 1 0 7 7 5 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS80191.1 - 1.6e-09 37.3 25.5 0.095 12.5 1.1 5.9 5 0 0 5 5 5 5 C2H2-type zinc-finger domain zf-met PF12874.7 RUS80191.1 - 4e-09 36.6 29.4 0.039 14.3 1.5 6.2 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS80191.1 - 2.9e-06 26.9 28.0 0.0014 18.3 0.8 5.4 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS80191.1 - 8.7e-05 22.4 1.2 8.7e-05 22.4 1.2 7.3 7 0 0 7 7 6 4 C2H2-type zinc finger GAGA PF09237.11 RUS80191.1 - 0.0063 16.3 9.8 1.5 8.7 0.1 4.0 1 1 3 4 4 4 2 GAGA factor zf-C2HE PF16278.5 RUS80191.1 - 0.0089 16.5 14.6 1.3 9.6 0.3 4.4 1 1 3 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 RUS80191.1 - 0.09 13.5 12.2 6.7 7.5 0.8 3.2 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 RUS80191.1 - 0.18 12.2 29.2 1.5 9.2 0.6 5.3 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS80191.1 - 0.28 11.4 13.7 6 7.1 0.6 4.5 3 2 0 4 4 4 0 Zinc ribbon domain DZR PF12773.7 RUS80191.1 - 0.38 10.8 10.1 0.29 11.2 1.3 2.9 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 RUS80191.1 - 2.7 8.1 9.6 2.3 8.3 0.4 2.7 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 RUS80191.1 - 3.6 7.6 22.9 1.2 9.1 0.8 4.4 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 RUS80191.1 - 5.9 7.5 11.9 11 6.6 2.4 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 RUS80191.1 - 6.3 6.9 15.8 2.7 8.0 2.0 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain XPA_N PF01286.18 RUS80191.1 - 9.8 6.3 9.9 18 5.5 0.1 4.2 4 0 0 4 4 4 0 XPA protein N-terminal WD40 PF00400.32 RUS80193.1 - 9.9e-05 23.0 13.8 0.096 13.6 1.3 5.2 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS80193.1 - 0.0002 21.6 0.3 0.99 9.8 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WH1 PF00568.23 RUS80194.1 - 6.6e-32 109.8 0.1 1.3e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 WH1 domain GAS PF13851.6 RUS80194.1 - 0.011 15.1 9.8 0.011 15.1 9.8 3.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 RUS80194.1 - 0.013 16.1 6.7 0.013 16.1 6.7 4.3 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Filament PF00038.21 RUS80194.1 - 0.017 14.8 2.1 0.017 14.8 2.1 4.2 1 1 2 3 3 3 0 Intermediate filament protein Taxilin PF09728.9 RUS80194.1 - 0.025 13.7 23.2 0.095 11.9 1.8 3.1 3 0 0 3 3 3 0 Myosin-like coiled-coil protein Jnk-SapK_ap_N PF09744.9 RUS80194.1 - 0.11 12.7 40.5 0.06 13.6 12.2 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4391 PF14335.6 RUS80194.1 - 0.21 11.3 0.1 0.21 11.3 0.1 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF4391) MCC-bdg_PDZ PF10506.9 RUS80194.1 - 0.36 10.9 17.8 1.4 9.0 1.2 4.5 2 2 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CBM_3 PF00942.18 RUS80194.1 - 0.43 11.0 2.8 0.28 11.6 0.6 1.8 2 0 0 2 2 1 0 Cellulose binding domain kleA_kleC PF17383.2 RUS80194.1 - 1.4 9.3 0.0 1.4 9.3 0.0 3.7 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A APG6_N PF17675.1 RUS80194.1 - 2.3 8.8 36.3 0.88 10.1 6.1 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region Pkinase PF00069.25 RUS80195.1 - 3.7e-42 144.5 0.0 7.4e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80195.1 - 9.2e-24 84.1 0.0 1.9e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80195.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like KH_1 PF00013.29 RUS80198.1 - 4.7e-23 80.8 1.7 4.8e-12 45.5 0.2 2.5 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 RUS80198.1 - 3.3e-11 42.8 6.0 5.4e-11 42.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS80198.1 - 3.3e-05 23.6 6.4 6.7e-05 22.7 6.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS80198.1 - 8.4e-05 22.8 7.0 0.00016 21.9 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS80198.1 - 0.00012 21.9 7.1 0.00024 20.9 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_4 PF13083.6 RUS80198.1 - 0.00037 20.3 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 KH domain zf-RING_UBOX PF13445.6 RUS80198.1 - 0.0033 17.4 2.4 0.0044 17.0 0.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS80198.1 - 0.0077 16.2 6.1 0.017 15.1 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain KH_2 PF07650.17 RUS80198.1 - 0.012 15.4 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 KH domain zf-C3HC4_4 PF15227.6 RUS80198.1 - 0.015 15.4 7.2 0.03 14.5 7.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 RUS80198.1 - 0.18 11.5 1.5 0.41 10.3 1.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 RUS80198.1 - 0.27 11.1 6.5 0.63 9.9 6.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 RUS80198.1 - 0.32 11.3 3.2 0.52 10.6 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 RUS80198.1 - 1.5 8.7 5.7 3.1 7.7 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ApbA PF02558.16 RUS80199.1 - 0.035 13.8 0.0 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HAUS-augmin3 PF14932.6 RUS80199.1 - 0.11 12.1 4.0 0.19 11.3 3.5 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 RUS80199.1 - 0.14 10.7 2.0 0.19 10.2 2.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LtuB PF17455.2 RUS80199.1 - 0.46 11.1 2.2 40 4.9 0.0 3.2 3 0 0 3 3 3 0 Late transcription unit B Snapin_Pallidin PF14712.6 RUS80199.1 - 1.8 9.0 8.9 0.34 11.4 2.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF3868 PF12984.7 RUS80200.1 - 1.8e-09 37.4 2.6 25 4.7 0.0 7.8 1 1 7 8 8 8 0 Domain of unknown function, B. Theta Gene description (DUF3868) SDA1 PF05285.12 RUS80200.1 - 0.00034 20.2 16.7 0.00034 20.2 16.7 2.8 2 1 0 2 2 2 1 SDA1 PPP4R2 PF09184.11 RUS80200.1 - 0.00068 19.3 9.2 0.00068 19.3 9.2 3.2 3 0 0 3 3 3 1 PPP4R2 BUD22 PF09073.10 RUS80200.1 - 0.00079 18.9 13.3 0.00079 18.9 13.3 2.7 2 1 0 2 2 2 1 BUD22 HIF-1a_CTAD PF08778.10 RUS80200.1 - 0.0013 18.3 0.3 2.7e+02 1.3 0.0 6.8 8 0 0 8 8 8 0 HIF-1 alpha C terminal transactivation domain SURF6 PF04935.12 RUS80200.1 - 0.003 17.4 3.0 0.003 17.4 3.0 3.2 3 0 0 3 3 3 2 Surfeit locus protein 6 Mpp10 PF04006.12 RUS80200.1 - 0.0049 15.4 21.5 0.0049 15.4 21.5 3.0 2 1 0 3 3 3 1 Mpp10 protein CobT PF06213.12 RUS80200.1 - 0.01 15.2 80.0 0.17 11.2 26.3 3.1 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT TRP PF06011.12 RUS80200.1 - 0.097 11.4 0.1 0.36 9.5 0.0 1.7 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Presenilin PF01080.17 RUS80200.1 - 2.2 7.0 39.4 1 8.1 21.6 2.2 2 0 0 2 2 2 0 Presenilin DTHCT PF08070.11 RUS80201.1 - 0.047 14.4 0.6 0.063 14.0 0.6 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region HTH_Tnp_IS1 PF12759.7 RUS80201.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 InsA C-terminal domain PE PF00934.20 RUS80202.1 - 0.021 15.1 2.1 0.081 13.3 0.2 2.7 2 1 1 3 3 3 0 PE family Phage_GP20 PF06810.11 RUS80202.1 - 0.08 12.7 18.7 0.47 10.3 0.6 4.1 3 1 2 5 5 5 0 Phage minor structural protein GP20 TTSSLRR PF12468.8 RUS80202.1 - 0.12 12.6 0.3 0.34 11.2 0.3 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein CENP-F_leu_zip PF10473.9 RUS80202.1 - 0.16 12.0 29.5 0.82 9.7 1.3 4.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1805 PF08827.11 RUS80202.1 - 0.18 12.2 1.2 1.7 9.0 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1805) Fez1 PF06818.15 RUS80202.1 - 0.27 11.7 21.9 1.1 9.6 19.0 2.8 2 1 0 2 2 2 0 Fez1 Snapin_Pallidin PF14712.6 RUS80202.1 - 0.3 11.5 16.1 4 7.9 0.0 4.8 2 1 1 4 4 4 0 Snapin/Pallidin BLOC1_2 PF10046.9 RUS80202.1 - 0.53 10.6 14.9 0.68 10.3 0.4 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 RUS80202.1 - 2 9.0 16.8 0.3 11.6 8.2 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region DASH_Duo1 PF08651.10 RUS80202.1 - 6.4 6.6 9.0 4 7.3 0.2 4.1 3 1 1 4 4 4 0 DASH complex subunit Duo1 Ribosomal_L27A PF00828.19 RUS80203.1 - 7.2e-17 62.3 0.0 1.2e-16 61.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SPATA1_C PF15743.5 RUS80205.1 - 4.9e-40 137.1 24.8 4.9e-40 137.1 24.8 2.9 1 1 1 2 2 2 1 Spermatogenesis-associated C-terminus Lig_chan-Glu_bd PF10613.9 RUS80206.1 - 7.2e-24 84.2 0.1 5.3e-23 81.4 0.0 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 RUS80206.1 - 1.3e-20 73.7 0.0 2.8e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS80206.1 - 1.9e-20 73.3 0.0 3.7e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 RUS80206.1 - 2.9e-08 33.2 0.0 5.5e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Bax1-I PF01027.20 RUS80206.1 - 9.4 6.0 8.9 0.28 11.0 2.4 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 HLH PF00010.26 RUS80209.1 - 2.2e-15 56.4 0.2 4e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lipase_GDSL_2 PF13472.6 RUS80210.1 - 0.0055 17.1 0.0 0.0084 16.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PC-Esterase PF13839.6 RUS80210.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Adeno_E3_CR1 PF02440.15 RUS80210.1 - 0.2 11.5 1.7 17 5.3 0.0 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ran_BP1 PF00638.18 RUS80211.1 - 1.1e-15 58.0 0.1 2.3e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain FGGY_C PF02782.16 RUS80212.1 - 3.5e-46 157.5 0.0 5.1e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 RUS80212.1 - 1.7e-22 80.2 0.2 3.8e-22 79.0 0.2 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Diphthamide_syn PF01866.17 RUS80213.1 - 3.1e-94 315.8 1.3 6.3e-94 314.8 1.3 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Abhydrolase_5 PF12695.7 RUS80213.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 RUS80214.1 - 3.2e-64 216.8 0.0 4.2e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80214.1 - 4e-37 127.9 0.0 5.5e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80214.1 - 1.4e-05 24.6 0.1 2.7e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RVT_1 PF00078.27 RUS80216.1 - 7e-41 140.2 0.0 1.4e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS80216.1 - 2.7e-12 46.6 0.0 6.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS80216.1 - 0.006 16.1 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C65 PF10275.9 RUS80216.1 - 0.2 11.1 3.5 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Peptidase C65 Otubain Cytochrom_B562 PF07361.11 RUS80216.1 - 2.5 8.8 6.4 6.7 7.4 0.1 3.4 3 0 0 3 3 3 0 Cytochrome b562 TPR_2 PF07719.17 RUS80218.1 - 3.9e-20 70.3 0.3 0.00051 20.0 0.0 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 RUS80218.1 - 1.4e-19 69.0 0.1 0.00018 21.2 0.0 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RUS80218.1 - 2.3e-08 34.2 0.5 0.31 12.0 0.2 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80218.1 - 1.3e-07 31.2 0.0 0.18 12.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS80218.1 - 2.6e-07 31.2 0.2 0.029 15.0 0.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80218.1 - 3.6e-06 27.2 10.2 5.3 7.4 0.0 7.4 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS80218.1 - 5.1e-06 26.1 1.9 0.57 9.9 0.0 4.5 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 RUS80218.1 - 8e-06 25.5 6.3 28 5.0 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS80218.1 - 4.1e-05 24.0 0.2 0.87 10.1 0.2 4.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS80218.1 - 0.0002 21.1 7.2 2 8.4 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat MscS_porin PF12795.7 RUS80218.1 - 0.19 11.3 5.2 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ANAPC5 PF12862.7 RUS80218.1 - 0.25 11.4 1.5 17 5.6 0.0 3.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 RUS80218.1 - 4.5 7.9 10.3 49 4.6 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat LMF1 PF06762.14 RUS80219.1 - 5.9e-92 309.1 0.8 6.8e-92 308.9 0.8 1.0 1 0 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.14 RUS80220.1 - 0.037 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipase maturation factor LRR_8 PF13855.6 RUS80221.1 - 7.2e-43 144.2 19.2 1.1e-09 38.0 0.7 8.0 5 2 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 RUS80221.1 - 8e-33 111.9 33.9 8.5e-05 22.8 0.3 9.5 5 2 6 11 11 11 10 Leucine Rich repeats (2 copies) COR PF16095.5 RUS80221.1 - 5.1e-11 42.7 0.0 1.3e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 RUS80221.1 - 9e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS80221.1 - 9.8e-07 28.5 0.1 2.2e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 Ras family LRR_1 PF00560.33 RUS80221.1 - 4e-06 26.6 34.6 11 7.0 0.0 12.7 13 1 0 13 13 12 1 Leucine Rich Repeat LRR_6 PF13516.6 RUS80221.1 - 1.7e-05 24.5 23.3 1.5 9.1 0.1 8.3 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.6 RUS80221.1 - 0.0001 21.8 10.4 0.005 16.4 0.6 4.3 1 1 0 3 3 3 2 Leucine-rich repeat MMR_HSR1 PF01926.23 RUS80221.1 - 0.0016 18.5 0.0 0.0047 17.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsmF_methylt_CI PF17126.5 RUS80221.1 - 0.0072 16.3 0.5 4.1 7.5 0.1 3.7 3 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain SRPRB PF09439.10 RUS80221.1 - 0.0089 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 RUS80221.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 RUS80221.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RUS80221.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 RUS80223.1 - 9.8e-17 61.0 2.6 0.0017 19.2 0.3 6.1 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS80223.1 - 1.4e-12 47.8 0.0 0.48 10.7 0.0 5.9 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RUS80223.1 - 5.3e-06 25.2 0.0 1.1e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 RUS80223.1 - 8.2e-05 22.1 0.3 1.5 8.1 0.0 3.7 2 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 RUS80223.1 - 0.013 15.4 0.0 0.47 10.5 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SGL PF08450.12 RUS80223.1 - 0.1 12.2 0.1 0.46 10.0 0.1 2.2 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region EphA2_TM PF14575.6 RUS80224.1 - 0.21 12.5 0.0 0.24 12.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 RUS80224.1 - 0.22 11.5 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Syndecan domain DUF3050 PF11251.8 RUS80225.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Calreticulin PF00262.18 RUS80226.1 - 1.8e-165 550.2 12.7 1.8e-165 550.2 12.7 1.4 2 0 0 2 2 2 1 Calreticulin family TRAP_alpha PF03896.16 RUS80226.1 - 0.0044 16.3 2.3 0.061 12.5 0.5 2.3 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.23 RUS80227.1 - 3.9e-57 193.5 0.7 3.9e-57 193.5 0.7 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS80227.1 - 8.8e-16 58.2 0.2 3.7e-15 56.2 0.2 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PTR2 PF00854.21 RUS80228.1 - 1.5e-53 182.1 2.1 8.5e-38 130.2 0.0 2.1 2 0 0 2 2 2 2 POT family DUF262 PF03235.14 RUS80229.1 - 0.00065 19.9 6.8 0.00065 19.9 6.8 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF262 RR_TM4-6 PF06459.12 RUS80229.1 - 0.003 17.4 57.9 0.0081 16.0 34.0 2.2 2 0 0 2 2 2 2 Ryanodine Receptor TM 4-6 LicD PF04991.13 RUS80229.1 - 0.0031 17.7 28.8 0.0031 17.7 28.8 2.3 2 0 0 2 2 2 1 LicD family Zip PF02535.22 RUS80229.1 - 0.0056 15.9 11.0 0.0056 15.9 11.0 2.3 2 0 0 2 2 2 1 ZIP Zinc transporter MecA PF05389.12 RUS80229.1 - 0.007 16.0 2.1 0.007 16.0 2.1 3.2 2 1 1 3 3 1 1 Negative regulator of genetic competence (MecA) CDC27 PF09507.10 RUS80229.1 - 0.016 14.6 74.2 0.019 14.4 44.5 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Vfa1 PF08432.10 RUS80229.1 - 0.12 12.7 87.9 0.029 14.7 50.1 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 RUS80229.1 - 0.31 9.8 27.7 1.1 7.9 19.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 RUS80229.1 - 0.34 9.2 11.0 2.6 6.3 8.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF2052 PF09747.9 RUS80229.1 - 0.41 10.8 39.4 0.43 10.7 23.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 RUS80229.1 - 0.66 9.7 45.7 0.32 10.7 6.4 2.2 2 0 0 2 2 2 0 AAA domain SLC12 PF03522.15 RUS80229.1 - 0.79 8.7 49.3 0.17 10.9 29.8 2.1 2 0 0 2 2 2 0 Solute carrier family 12 CCSAP PF15748.5 RUS80229.1 - 2.6 8.2 63.9 1.8 8.7 39.5 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated GPCR_chapero_1 PF11904.8 RUS80229.1 - 3.8 6.8 39.3 2.2 7.6 23.9 2.2 2 0 0 2 2 2 0 GPCR-chaperone NPR3 PF03666.13 RUS80229.1 - 7.6 5.2 59.7 0.015 14.1 29.9 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase_fungal PF17667.1 RUS80229.1 - 9.4 4.9 24.2 0.65 8.7 11.4 2.1 2 0 0 2 2 2 0 Fungal protein kinase MFS_1 PF07690.16 RUS80230.1 - 2.4e-06 26.7 11.1 6.6e-06 25.3 10.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MTP18 PF10558.9 RUS80231.1 - 0.0069 16.4 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Citrate_synt PF00285.21 RUS80232.1 - 3.6e-105 352.0 0.0 4.4e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ras PF00071.22 RUS80233.1 - 1.3e-51 174.4 0.0 1.5e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS80233.1 - 7.7e-20 71.3 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS80233.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS80233.1 - 0.00015 21.4 0.0 0.00039 20.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RUS80233.1 - 0.00021 21.2 0.0 0.0028 17.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RUS80233.1 - 0.0056 16.6 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS80233.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS80233.1 - 0.074 13.4 0.1 0.55 10.6 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain LicD PF04991.13 RUS80234.1 - 6e-17 62.5 1.1 2.4e-12 47.5 1.0 2.2 1 1 1 2 2 2 2 LicD family WBP-1 PF11669.8 RUS80235.1 - 2.4 8.8 19.4 38 5.0 19.4 2.7 1 1 0 1 1 1 0 WW domain-binding protein 1 RAI16-like PF10257.9 RUS80236.1 - 3.3e-97 325.6 3.1 6.4e-97 324.7 3.1 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PFEMP PF03011.15 RUS80236.1 - 7.4 7.2 15.8 3.9 8.1 10.6 2.7 2 1 0 2 2 2 0 PFEMP DBL domain Spaetzle PF16077.5 RUS80237.1 - 7.7e-05 23.2 0.9 0.00026 21.5 0.9 1.9 1 1 0 1 1 1 1 Spaetzle HRM PF02793.22 RUS80239.1 - 4.7e-08 33.2 1.1 4.7e-08 33.2 1.1 2.1 2 0 0 2 2 2 1 Hormone receptor domain DUF2567 PF10821.8 RUS80239.1 - 0.087 12.9 0.9 0.2 11.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) LRR_4 PF12799.7 RUS80240.1 - 0.0012 19.2 21.0 0.0021 18.4 3.1 5.7 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) zf-RING_UBOX PF13445.6 RUS80241.1 - 0.00012 22.1 8.5 0.00026 21.0 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Atg14 PF10186.9 RUS80241.1 - 0.00045 19.4 7.4 0.00045 19.4 7.4 2.2 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_5 PF14634.6 RUS80241.1 - 0.0022 17.9 16.0 0.0044 17.0 16.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS80241.1 - 0.0028 17.5 10.8 0.006 16.4 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RUS80241.1 - 0.0051 16.6 10.3 0.01 15.7 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS80241.1 - 0.0082 16.5 10.1 0.017 15.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS80241.1 - 0.011 15.6 10.6 0.027 14.3 10.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF724 PF05266.14 RUS80241.1 - 0.015 15.2 8.2 0.015 15.2 8.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF724) TRAF_BIRC3_bd PF16673.5 RUS80241.1 - 0.016 15.0 0.7 0.016 15.0 0.7 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 RUS80241.1 - 0.65 10.0 10.6 0.035 14.1 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 RUS80241.1 - 0.76 8.6 18.9 0.47 9.3 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Par3_HAL_N_term PF12053.8 RUS80241.1 - 0.82 9.9 3.2 1.3 9.3 0.2 2.9 3 1 1 4 4 4 0 N-terminal of Par3 and HAL proteins zf-UDP PF14569.6 RUS80241.1 - 1.4 9.1 7.6 1.7 8.8 6.3 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger FPP PF05911.11 RUS80241.1 - 1.7 6.7 27.0 7.1 4.7 27.0 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 RUS80241.1 - 2.6 8.6 20.5 0.18 12.3 10.7 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Dyp_perox PF04261.12 RUS80242.1 - 6e-41 140.5 0.0 7.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Mak10 PF04112.13 RUS80243.1 - 8.6e-30 103.5 0.5 7e-23 81.0 0.2 2.7 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase 23S_rRNA_IVP PF05635.11 RUS80243.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Myosin_head PF00063.21 RUS80244.1 - 2.5e-214 713.4 0.6 3e-214 713.1 0.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 RUS80244.1 - 0.0068 16.7 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS80244.1 - 0.0087 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RUS80244.1 - 0.023 15.2 0.1 0.28 11.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Glyco_transf_20 PF00982.21 RUS80244.1 - 0.037 12.7 0.2 0.083 11.5 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 20 AAA_19 PF13245.6 RUS80244.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer2 PF00111.27 RUS80244.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SH2 PF00017.24 RUS80245.1 - 2.1e-17 63.0 0.2 5.1e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 SH2 domain DUF1797 PF08796.10 RUS80245.1 - 0.039 14.0 0.7 0.1 12.7 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) PRODH PF18327.1 RUS80245.1 - 0.13 12.5 2.4 0.31 11.3 2.4 1.6 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain Ciart PF15673.5 RUS80246.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.6 2 0 0 2 2 2 0 Circadian-associated transcriptional repressor tRNA_anti_2 PF13742.6 RUS80246.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Lectin_C PF00059.21 RUS80247.1 - 4e-07 30.7 0.4 1.1e-06 29.3 0.4 1.8 1 0 0 1 1 1 1 Lectin C-type domain Ig_3 PF13927.6 RUS80247.1 - 0.00035 21.1 1.6 0.00088 19.8 0.4 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS80247.1 - 0.01 16.0 0.7 0.024 14.8 0.7 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 RUS80247.1 - 0.1 12.9 0.7 0.3 11.4 0.7 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Lectin_C PF00059.21 RUS80248.1 - 2.8e-17 63.4 0.3 2.4e-05 25.0 0.0 3.2 3 0 0 3 3 3 3 Lectin C-type domain UK PF02512.14 RUS80250.1 - 0.003 18.1 2.2 2.4 8.8 0.1 3.2 1 1 1 3 3 3 2 Virulence determinant GREB1 PF15782.5 RUS80250.1 - 6.4 3.7 46.8 7.1 3.6 46.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lectin_C PF00059.21 RUS80251.1 - 5.6e-15 56.0 0.0 2.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Lectin C-type domain Xlink PF00193.17 RUS80251.1 - 0.12 12.8 0.3 3.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Extracellular link domain GBP PF02263.19 RUS80251.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ephrin_rec_like PF07699.13 RUS80252.1 - 8.1e-10 38.3 214.0 0.2 11.4 1.3 18.3 7 5 8 16 16 16 14 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80254.1 - 0.00011 21.9 145.8 0.0042 16.8 4.2 15.7 8 6 6 14 14 14 13 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80255.1 - 6.6e-06 25.8 5.7 6.6e-06 25.8 5.7 7.9 2 1 7 9 9 9 4 Putative ephrin-receptor like Lustrin_cystein PF14625.6 RUS80255.1 - 0.044 14.1 67.3 0.73 10.3 0.4 8.9 3 2 4 7 7 7 0 Lustrin, cysteine-rich repeated domain FOLN PF09289.10 RUS80255.1 - 0.068 13.4 6.9 1.6 9.0 0.1 4.5 4 0 0 4 4 4 0 Follistatin/Osteonectin-like EGF domain TNFR_c6 PF00020.18 RUS80255.1 - 2.3 8.7 0.0 0.91 10.0 1.7 7.5 6 2 2 8 8 8 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS80256.1 - 3.1e-07 30.0 31.7 4.8e-05 23.0 2.0 85.1 61 23 25 88 88 88 52 Putative ephrin-receptor like Ldl_recept_a PF00057.18 RUS80256.1 - 0.045 14.0 11.5 0.47 10.7 0.1 8.1 4 0 0 4 4 4 0 Low-density lipoprotein receptor domain class A ATG16 PF08614.11 RUS80256.1 - 0.73 10.0 6.7 1.1 9.5 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TSP_NTD PF17804.1 RUS80257.1 - 0.011 16.0 0.3 0.019 15.2 0.3 1.4 1 0 0 1 1 1 0 Tail specific protease N-terminal domain FmiP_Thoc5 PF09766.9 RUS80257.1 - 0.075 12.3 5.2 0.079 12.2 4.2 1.6 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Metalloenzyme PF01676.18 RUS80257.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Metalloenzyme superfamily DUF3563 PF12086.8 RUS80257.1 - 0.21 11.4 2.3 0.5 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) Laminin_G_2 PF02210.24 RUS80259.1 - 1.1e-07 32.5 0.1 2.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS80259.1 - 1.5e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain SUI1 PF01253.22 RUS80260.1 - 5.7e-26 90.9 0.9 9.2e-26 90.2 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 IPK PF03770.16 RUS80261.1 - 2.2e-28 99.5 0.1 9.9e-28 97.3 0.1 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF2207 PF09972.9 RUS80262.1 - 0.35 9.6 5.9 0.44 9.3 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.11 RUS80262.1 - 2.4 7.6 14.3 3.3 7.2 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MgtE PF01769.16 RUS80262.1 - 9 6.7 19.1 14 6.1 19.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter Ferritin PF00210.24 RUS80263.1 - 8.7e-37 126.2 0.4 1e-36 126.0 0.4 1.1 1 0 0 1 1 1 1 Ferritin-like domain IcmF_C PF06744.12 RUS80263.1 - 0.078 12.6 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal FliS_cochap PF16522.5 RUS80263.1 - 0.1 12.5 1.3 2.8 7.9 0.3 2.1 1 1 1 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 DUF5524 PF17662.1 RUS80264.1 - 8e-19 68.1 8.1 3.2e-18 66.1 8.1 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5524) WD40 PF00400.32 RUS80265.1 - 3.8e-28 97.1 30.5 2.4e-05 25.0 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS80265.1 - 9.8e-17 61.0 2.2 0.022 15.0 0.0 6.0 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS80265.1 - 9.4e-10 38.7 0.1 0.00013 21.9 0.1 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RUS80265.1 - 4.4e-07 29.5 0.0 0.028 13.7 0.0 3.2 2 1 1 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 RUS80265.1 - 5.8e-07 28.8 3.3 0.028 13.4 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 RUS80265.1 - 0.0046 16.3 0.7 4.4 6.5 0.0 3.9 3 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RUS80265.1 - 0.07 11.8 0.4 2.9 6.4 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 RUS80265.1 - 0.63 8.9 4.1 1.5 7.6 1.2 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain TIMELESS_C PF05029.13 RUS80265.1 - 5.8 5.9 8.7 7.3 5.6 8.7 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region HS1_rep PF02218.15 RUS80266.1 - 0.0033 17.7 0.3 20 5.6 0.0 4.5 2 2 4 6 6 6 2 Repeat in HS1/Cortactin Cons_hypoth698 PF03601.14 RUS80266.1 - 0.19 10.5 0.1 46 2.8 0.0 3.1 1 1 4 5 5 5 0 Conserved hypothetical protein 698 TMEM210 PF15195.6 RUS80266.1 - 1.3 9.4 5.2 31 5.0 0.2 3.1 1 1 2 3 3 3 0 TMEM210 family WXG100 PF06013.12 RUS80267.1 - 0.018 15.3 0.0 0.076 13.3 0.0 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF2798 PF11391.8 RUS80268.1 - 6.5e-06 26.1 42.3 0.02 14.9 10.5 5.5 1 1 3 4 4 4 3 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RUS80268.1 - 0.0021 18.0 9.6 0.6 10.1 3.0 4.1 2 2 1 3 3 3 3 Glycine zipper MscL PF01741.18 RUS80268.1 - 0.019 15.3 0.2 13 6.1 0.1 2.9 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL Colicin_V PF02674.16 RUS80268.1 - 0.044 13.7 25.5 0.36 10.8 10.6 2.5 1 1 1 2 2 2 0 Colicin V production protein Reprolysin_5 PF13688.6 RUS80269.1 - 0.0021 18.2 0.1 0.0037 17.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS80269.1 - 0.0039 17.7 0.1 0.0058 17.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS80269.1 - 0.063 13.2 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.11 RUS80270.1 - 0.088 13.6 0.9 0.088 13.6 0.9 6.3 5 1 0 5 5 5 0 PLAC (protease and lacunin) domain Crisp PF08562.10 RUS80271.1 - 0.027 15.1 4.8 0.027 15.1 4.8 2.3 2 0 0 2 2 2 0 Crisp zf-C3HC4_3 PF13920.6 RUS80272.1 - 2e-08 33.9 10.2 4.1e-08 33.0 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS80272.1 - 0.01 15.7 10.9 0.011 15.5 9.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS80272.1 - 0.015 15.3 11.5 0.015 15.3 11.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Sas6_CC PF18594.1 RUS80272.1 - 0.032 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain zf-RING_2 PF13639.6 RUS80272.1 - 1.4 9.3 12.1 5.5 7.4 12.1 2.1 1 0 0 1 1 1 0 Ring finger domain ParA PF10609.9 RUS80273.1 - 2.3e-74 250.0 0.1 2.6e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RUS80273.1 - 2.7e-08 33.9 0.0 9.9e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RUS80273.1 - 2.4e-06 27.2 0.1 0.0051 16.3 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 RUS80273.1 - 0.00062 19.1 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 RUS80273.1 - 0.0061 16.5 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 RUS80273.1 - 0.014 14.6 1.7 0.41 9.8 0.6 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase Mvb12 PF09452.10 RUS80274.1 - 0.0009 19.6 0.1 0.0012 19.3 0.1 1.2 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 RAI16-like PF10257.9 RUS80274.1 - 0.077 11.9 0.2 0.088 11.7 0.2 1.0 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein Asparaginase_2 PF01112.18 RUS80275.1 - 4.8e-47 160.5 0.9 5.6e-47 160.2 0.9 1.0 1 0 0 1 1 1 1 Asparaginase Asparaginase_2 PF01112.18 RUS80276.1 - 3.7e-65 219.9 6.4 8.1e-51 172.9 0.8 2.0 1 1 1 2 2 2 2 Asparaginase Glyco_hydro_42C PF08533.10 RUS80276.1 - 0.091 12.5 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain FAD_binding_7 PF03441.14 RUS80278.1 - 3e-60 203.2 0.1 4.4e-60 202.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RUS80278.1 - 6.7e-37 127.0 0.0 1.6e-36 125.8 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Lectin_C PF00059.21 RUS80279.1 - 8e-07 29.8 0.0 9.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 RUS80279.1 - 0.0048 16.2 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A33R protein DUF5075 PF16825.5 RUS80279.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 IGP family C-type lectin domain HAT PF02184.16 RUS80280.1 - 2e-36 123.6 70.3 1.4e-19 69.7 2.7 13.3 14 2 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 RUS80280.1 - 1.7e-23 81.2 28.2 0.02 15.7 0.0 12.4 8 3 6 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 RUS80280.1 - 1.5e-15 57.4 1.0 0.14 12.7 0.0 8.6 4 2 4 10 10 10 2 Tetratricopeptide repeat Suf PF05843.14 RUS80280.1 - 2.5e-13 50.7 31.7 7.4e-06 26.2 3.6 5.8 1 1 3 4 4 4 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 RUS80280.1 - 8.5e-10 38.0 10.5 0.46 10.7 0.1 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS80280.1 - 2.5e-09 37.6 7.8 0.76 10.5 0.6 7.7 8 2 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80280.1 - 5.9e-09 35.4 0.3 4.6 7.7 0.0 7.0 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS80280.1 - 6.3e-09 35.6 3.9 0.0031 17.8 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RUS80280.1 - 2.4e-06 27.5 24.0 0.02 14.9 0.7 7.5 7 1 0 8 8 8 3 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 RUS80280.1 - 4.6e-06 26.7 2.6 2.2 8.5 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS80280.1 - 0.00012 21.4 15.2 0.076 12.2 0.1 5.2 2 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS80280.1 - 0.00018 21.9 13.8 1.9 9.3 0.1 8.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80280.1 - 0.00034 20.8 13.9 1.1 9.7 0.1 6.1 6 1 2 8 8 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS80280.1 - 0.0073 16.1 0.1 5.1 7.1 0.1 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS80280.1 - 0.017 15.2 1.8 31 4.7 0.1 4.7 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 RUS80280.1 - 0.019 15.0 18.4 0.024 14.7 0.6 6.5 5 3 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.6 RUS80280.1 - 0.024 14.6 8.2 0.71 10.0 0.2 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS80280.1 - 0.045 13.4 0.1 5.1 6.9 0.0 4.1 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 RUS80280.1 - 0.51 11.1 8.0 35 5.4 0.1 5.1 6 0 0 6 6 3 0 Tetratricopeptide repeat Kazal_2 PF07648.15 RUS80282.1 - 1.6e-08 34.5 5.4 1.6e-08 34.5 5.4 3.6 5 0 0 5 5 5 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS80282.1 - 5.6e-07 29.5 6.1 5.6e-07 29.5 6.1 3.1 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain CRT-like PF08627.10 RUS80283.1 - 1.1e-08 34.4 6.8 1.1e-08 34.4 6.8 2.0 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 RUS80283.1 - 3.1e-08 33.3 0.3 3.9e-08 33.0 0.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 RUS80283.1 - 4.8e-08 32.9 3.6 4.8e-08 32.9 3.6 2.3 3 0 0 3 3 3 1 Solute carrier family 35 EamA PF00892.20 RUS80283.1 - 4.8e-07 30.0 21.0 1.8e-06 28.1 5.6 3.4 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 RUS80283.1 - 6.4e-07 28.9 0.2 8.6e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter Bax1-I PF01027.20 RUS80283.1 - 0.00024 21.0 5.8 0.00024 21.0 5.8 2.5 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 PUNUT PF16913.5 RUS80283.1 - 0.00048 19.5 1.0 0.00048 19.5 1.0 2.3 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport PhoLip_ATPase_C PF16212.5 RUS80283.1 - 0.01 15.6 3.7 0.01 15.6 3.7 2.0 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal UAA PF08449.11 RUS80283.1 - 0.038 13.2 6.6 0.088 12.0 6.7 1.5 1 1 0 1 1 1 0 UAA transporter family DUF373 PF04123.13 RUS80283.1 - 0.58 9.5 7.5 0.053 12.9 1.9 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF373) E1_DerP2_DerF2 PF02221.15 RUS80284.1 - 3.2e-18 66.5 0.0 4.4e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 ML domain PAS_11 PF14598.6 RUS80285.1 - 2.4e-25 88.9 0.1 1.6e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 RUS80285.1 - 6.5e-22 77.6 0.0 4.8e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 RUS80285.1 - 1.1e-16 60.8 0.1 3e-08 33.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold HIF-1a_CTAD PF08778.10 RUS80285.1 - 2.6e-11 42.9 1.1 5.5e-11 41.9 1.1 1.6 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain PAS_9 PF13426.7 RUS80285.1 - 6.8e-11 42.4 0.0 0.00067 19.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 RUS80285.1 - 1.4e-08 35.0 0.0 0.0044 17.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold HIF-1 PF11413.8 RUS80285.1 - 0.00085 18.7 2.1 0.06 12.8 0.3 2.8 2 0 0 2 2 2 2 Hypoxia-inducible factor-1 Lig_chan PF00060.26 RUS80287.1 - 2e-14 53.7 0.1 2.7e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS80287.1 - 4.8e-09 36.0 0.0 8.4e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 RUS80287.1 - 9.6e-06 25.8 0.1 2.2e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site EphA2_TM PF14575.6 RUS80288.1 - 0.033 15.1 0.0 0.073 14.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 RUS80288.1 - 0.14 12.9 4.0 0.3 11.8 3.6 1.8 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4083 PF13314.6 RUS80288.1 - 0.26 11.3 0.3 0.46 10.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Rer1 PF03248.13 RUS80291.1 - 3.5e-76 254.7 6.8 4.5e-76 254.4 6.8 1.1 1 0 0 1 1 1 1 Rer1 family DUF4191 PF13829.6 RUS80291.1 - 0.065 12.6 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Halogen_Hydrol PF10112.9 RUS80291.1 - 0.11 12.5 0.8 15 5.5 0.4 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sec62 PF03839.16 RUS80292.1 - 8.6e-69 231.3 10.1 8.6e-69 231.3 10.1 2.5 2 1 1 3 3 3 1 Translocation protein Sec62 DUF2207 PF09972.9 RUS80292.1 - 4.4e-05 22.5 0.1 4.4e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Smg8_Smg9 PF10220.9 RUS80292.1 - 0.0015 16.9 0.5 0.0015 16.9 0.5 2.1 2 0 0 2 2 2 1 Smg8_Smg9 Zip PF02535.22 RUS80292.1 - 0.0035 16.6 14.3 0.045 13.0 7.7 2.5 2 0 0 2 2 2 2 ZIP Zinc transporter DEP PF00610.21 RUS80292.1 - 0.016 15.2 0.1 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF966 PF06136.13 RUS80292.1 - 0.49 10.1 23.7 0.12 12.0 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) SID-1_RNA_chan PF13965.6 RUS80292.1 - 0.68 8.3 7.4 2 6.7 0.0 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Folliculin PF11704.8 RUS80292.1 - 6.3 6.6 10.8 0.12 12.3 2.9 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport wnt PF00110.19 RUS80293.1 - 9.6e-51 173.2 4.0 1.2e-50 172.9 4.0 1.1 1 0 0 1 1 1 1 wnt family Zot PF05707.12 RUS80293.1 - 0.06 13.0 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF374 PF04028.13 RUS80294.1 - 0.0063 16.1 0.3 0.06 12.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF374) MCM PF00493.23 RUS80296.1 - 8.3e-102 339.0 0.1 3.1e-101 337.2 0.0 1.9 1 1 1 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 RUS80296.1 - 2.1e-34 118.1 1.3 4.1e-34 117.1 1.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 RUS80296.1 - 5e-32 110.4 1.2 1.3e-31 109.0 1.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 RUS80296.1 - 1.8e-27 95.6 0.5 5e-27 94.2 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RUS80296.1 - 1.5e-18 67.3 0.3 3.9e-18 65.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RUS80296.1 - 1e-06 28.3 0.0 3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RUS80296.1 - 6.6e-05 22.8 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS80296.1 - 0.00027 21.0 0.0 0.00076 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RUS80296.1 - 0.0061 16.3 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 RUS80296.1 - 0.41 11.3 2.0 1.4 9.6 0.4 2.8 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal NOG1_N PF17835.1 RUS80297.1 - 1.2e-48 165.2 0.6 1.2e-48 165.2 0.6 2.6 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 RUS80297.1 - 4.9e-25 87.1 0.2 1.1e-24 85.9 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 RUS80297.1 - 9e-24 83.2 3.3 3.1e-23 81.5 3.3 2.0 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 RUS80297.1 - 3.8e-19 68.9 0.2 1e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS80297.1 - 1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS80297.1 - 6.4e-06 26.2 1.7 0.15 12.0 0.0 3.6 4 1 0 4 4 4 2 RsgA GTPase AIG1 PF04548.16 RUS80297.1 - 0.001 18.4 0.3 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 AIG1 family Gtr1_RagA PF04670.12 RUS80297.1 - 0.0026 17.2 0.5 0.0056 16.1 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS80297.1 - 0.0046 16.5 2.8 0.0058 16.2 0.2 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RUS80297.1 - 0.012 15.0 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 RUS80297.1 - 0.013 15.6 12.6 0.32 11.1 0.0 4.1 2 2 2 4 4 4 0 Dynamin family Roc PF08477.13 RUS80297.1 - 0.019 15.2 0.0 0.13 12.5 0.0 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS80297.1 - 0.042 14.2 0.0 0.3 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 RUS80297.1 - 0.073 12.8 0.1 6 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCR_alpha_N PF02745.15 RUS80297.1 - 0.12 11.7 1.3 0.33 10.3 1.3 1.7 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Septin PF00735.18 RUS80297.1 - 0.21 10.8 4.8 1.4 8.1 0.2 3.2 2 1 1 3 3 3 0 Septin baeRF_family12 PF18856.1 RUS80297.1 - 2.6 8.6 7.4 0.19 12.3 1.6 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Trypsin_2 PF13365.6 RUS80298.1 - 2.3e-08 35.1 0.1 6.8e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.20 RUS80298.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Trypsin PF00089.26 RUS80298.1 - 0.072 12.9 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Trypsin Mon2_C PF16206.5 RUS80299.1 - 6.4e-281 934.1 0.0 7.6e-281 933.8 0.0 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 RUS80299.1 - 2.2e-15 56.2 0.0 7.4e-15 54.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) bZIP_2 PF07716.15 RUS80300.1 - 4.7e-13 49.0 12.1 9e-13 48.1 12.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS80300.1 - 0.0011 19.0 12.2 0.0011 19.0 12.2 1.6 2 0 0 2 2 2 1 bZIP transcription factor Macoilin PF09726.9 RUS80300.1 - 9.1 4.7 9.8 0.41 9.1 2.7 2.0 2 0 0 2 2 2 0 Macoilin family HIGH_NTase1_ass PF16581.5 RUS80302.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Phage_SSB PF16773.5 RUS80303.1 - 0.023 14.8 14.6 50 4.0 0.5 6.0 1 1 2 3 3 3 0 Lactococcus phage single-stranded DNA binding protein HCBP_related PF06594.11 RUS80303.1 - 3.4 7.7 20.6 0.63 10.0 0.6 5.8 1 1 3 4 4 4 0 Haemolysin-type calcium binding protein related domain DIT1_PvcA PF05141.12 RUS80303.1 - 5.1 6.5 14.2 4.4 6.7 2.9 3.8 1 1 2 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein RST PF12174.8 RUS80304.1 - 0.12 12.4 0.2 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain RBDV_coat PF06593.11 RUS80305.1 - 0.11 12.0 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein NS3_envE PF02723.14 RUS80305.1 - 0.15 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Citrus_P18 PF05520.11 RUS80306.1 - 0.014 15.1 0.1 0.032 13.9 0.1 1.6 2 0 0 2 2 2 0 Citrus tristeza virus P18 protein DUF1542 PF07564.11 RUS80306.1 - 0.086 13.0 0.7 0.16 12.1 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) YtzH PF14165.6 RUS80306.1 - 0.13 12.7 0.1 0.43 11.0 0.1 1.7 1 1 1 2 2 2 0 YtzH-like protein Gelsolin PF00626.22 RUS80307.1 - 4.5e-43 145.0 0.6 2.2e-13 49.9 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat zf-C3HC4_4 PF15227.6 RUS80308.1 - 1.5e-10 41.0 4.3 1.5e-10 41.0 4.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS80308.1 - 2.8e-09 36.9 1.7 2.8e-09 36.9 1.7 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS80308.1 - 3e-09 36.6 4.7 6.5e-09 35.5 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS80308.1 - 2.3e-07 30.5 2.5 2.3e-07 30.5 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS80308.1 - 1.2e-06 28.4 6.5 2.3e-06 27.4 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS80308.1 - 1.8e-05 25.0 6.6 4.5e-05 23.7 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS80308.1 - 8.1e-05 22.4 7.8 0.00037 20.3 7.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RUS80308.1 - 0.0013 18.5 3.1 0.0034 17.1 3.1 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 RUS80308.1 - 0.044 13.9 1.3 0.044 13.9 1.3 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 RUS80308.1 - 0.061 13.2 2.0 0.2 11.6 2.0 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 RUS80308.1 - 0.64 10.1 3.4 1.6 8.8 3.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 RUS80308.1 - 1.2 9.1 6.9 6.1 6.8 6.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Integrase_H2C2 PF17921.1 RUS80308.1 - 1.8 8.7 5.5 6.6 6.9 0.7 2.5 2 0 0 2 2 2 0 Integrase zinc binding domain FYVE PF01363.21 RUS80308.1 - 2.4 8.4 8.1 8 6.7 7.8 1.9 1 1 1 2 2 2 0 FYVE zinc finger ADP_ribosyl_GH PF03747.14 RUS80309.1 - 1.3e-49 169.5 0.1 1.6e-49 169.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PAS_3 PF08447.12 RUS80310.1 - 1.7e-16 60.3 0.0 6.5e-12 45.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 RUS80310.1 - 6e-14 52.1 5.3 1.1e-13 51.3 0.1 3.2 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 RUS80310.1 - 5.7e-09 36.0 1.2 6.8e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 RUS80310.1 - 0.00036 20.8 0.1 0.018 15.2 0.0 2.8 3 0 0 3 3 3 1 PAS domain LptC PF06835.13 RUS80310.1 - 0.0094 15.5 0.2 0.024 14.2 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related PAS_2 PF08446.11 RUS80310.1 - 0.022 15.4 0.0 0.1 13.3 0.0 2.1 1 0 0 1 1 1 0 PAS fold AAA PF00004.29 RUS80311.1 - 7.2e-76 253.0 0.0 1.1e-42 145.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ETF_QO PF05187.13 RUS80311.1 - 2.1e-28 98.5 0.0 8e-28 96.6 0.0 2.0 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S AAA_lid_3 PF17862.1 RUS80311.1 - 1e-22 79.7 2.0 1.2e-11 44.2 0.1 3.6 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 RUS80311.1 - 2.3e-10 41.1 1.6 4.2e-06 27.2 0.6 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 RUS80311.1 - 2.8e-09 37.1 0.0 0.003 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DAO PF01266.24 RUS80311.1 - 7e-09 35.7 0.2 5.1e-05 23.0 0.6 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS80311.1 - 1.9e-07 30.6 0.9 2.9e-06 26.7 1.4 2.2 2 0 0 2 2 2 1 FAD binding domain RuvB_N PF05496.12 RUS80311.1 - 2.6e-07 30.5 0.0 0.034 13.9 0.0 3.3 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS80311.1 - 4.6e-07 30.1 0.0 0.023 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Thi4 PF01946.17 RUS80311.1 - 5.8e-07 29.0 0.0 2.6e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Mg_chelatase PF01078.21 RUS80311.1 - 6.5e-07 28.9 0.5 0.014 14.8 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NAD_binding_8 PF13450.6 RUS80311.1 - 6.9e-07 29.4 0.1 2.9e-06 27.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RUS80311.1 - 2.9e-06 26.7 0.0 5.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IstB_IS21 PF01695.17 RUS80311.1 - 3.2e-06 27.0 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 RUS80311.1 - 4.3e-06 26.8 0.0 0.061 13.2 0.0 3.0 3 0 0 3 3 2 2 Rad17 P-loop domain DUF815 PF05673.13 RUS80311.1 - 4.7e-06 25.9 0.0 2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 RUS80311.1 - 5.3e-06 25.9 0.0 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain FAD_oxidored PF12831.7 RUS80311.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase RNA_helicase PF00910.22 RUS80311.1 - 3.3e-05 24.2 0.0 0.086 13.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 RUS80311.1 - 3.5e-05 24.0 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS80311.1 - 4.3e-05 23.8 2.6 0.058 13.7 0.6 4.5 2 2 2 4 4 4 1 AAA domain Pyr_redox PF00070.27 RUS80311.1 - 0.00012 22.6 0.1 0.18 12.4 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RUS80311.1 - 0.00015 20.8 0.6 0.0028 16.6 0.2 2.4 3 0 0 3 3 2 1 Tryptophan halogenase TsaE PF02367.17 RUS80311.1 - 0.00015 21.8 0.0 0.015 15.3 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NAD_binding_9 PF13454.6 RUS80311.1 - 0.00022 21.2 0.1 0.00064 19.7 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding AAA_28 PF13521.6 RUS80311.1 - 0.0004 20.7 0.0 0.084 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain HI0933_like PF03486.14 RUS80311.1 - 0.00058 18.7 0.6 0.001 17.8 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein AAA_7 PF12775.7 RUS80311.1 - 0.00064 19.3 0.0 0.052 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region FAD_binding_3 PF01494.19 RUS80311.1 - 0.00069 19.0 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NACHT PF05729.12 RUS80311.1 - 0.0012 18.8 0.1 2.1 8.2 0.1 3.6 3 0 0 3 3 3 1 NACHT domain Lycopene_cycl PF05834.12 RUS80311.1 - 0.0015 17.6 0.2 0.0025 16.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AAA_18 PF13238.6 RUS80311.1 - 0.0035 17.9 0.0 0.4 11.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 RUS80311.1 - 0.0042 17.1 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RUS80311.1 - 0.0072 15.9 3.1 1.9 8.0 0.3 3.6 2 2 2 4 4 4 1 AAA domain Pyr_redox_3 PF13738.6 RUS80311.1 - 0.0085 15.4 0.6 0.0085 15.4 0.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_30 PF13604.6 RUS80311.1 - 0.017 14.8 0.0 0.083 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 RUS80311.1 - 0.019 14.8 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RUS80311.1 - 0.033 14.1 0.0 1.5 8.6 0.0 2.8 2 2 2 4 4 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RUS80311.1 - 0.033 14.7 0.0 0.83 10.2 0.0 2.8 3 0 0 3 3 2 0 ABC transporter Bac_DnaA PF00308.18 RUS80311.1 - 0.044 13.6 0.0 7.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.26 RUS80311.1 - 0.052 13.3 0.0 1 9.0 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_6 PF12774.7 RUS80311.1 - 0.062 12.3 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Parvo_NS1 PF01057.17 RUS80311.1 - 0.063 12.4 0.0 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SSE PF00437.20 RUS80311.1 - 0.072 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RUS80311.1 - 0.077 12.9 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_11 PF13086.6 RUS80311.1 - 0.084 12.6 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 RUS80311.1 - 0.093 11.9 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase KAP_NTPase PF07693.14 RUS80311.1 - 0.13 11.5 0.2 0.91 8.7 0.1 2.1 2 1 0 2 2 2 0 KAP family P-loop domain Cytidylate_kin PF02224.18 RUS80311.1 - 0.14 11.9 0.2 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 RUS80311.1 - 0.14 11.9 0.0 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GIDA PF01134.22 RUS80311.1 - 0.14 11.2 0.2 0.24 10.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Sigma54_activ_2 PF14532.6 RUS80311.1 - 0.15 12.2 0.0 24 5.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 RUS80311.1 - 0.17 11.4 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Isochorismatase PF00857.20 RUS80313.1 - 1.7e-26 93.4 0.3 5.4e-26 91.8 0.3 1.8 1 1 0 1 1 1 1 Isochorismatase family EF-hand_1 PF00036.32 RUS80313.1 - 5e-13 47.6 4.3 8.4e-06 25.0 1.6 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS80313.1 - 1.1e-12 46.8 3.3 1e-05 25.1 0.8 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS80313.1 - 3.4e-12 46.0 5.0 1.6e-05 24.7 0.8 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 RUS80313.1 - 5.2e-11 42.8 2.7 6.3e-11 42.6 1.4 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS80313.1 - 2.3e-10 39.5 12.7 2e-05 23.9 0.6 2.9 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 RUS80313.1 - 0.00094 19.5 0.1 0.0047 17.2 0.1 2.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS80313.1 - 0.37 10.8 3.5 3.1 7.8 0.1 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand SSF PF00474.17 RUS80315.1 - 6.5e-133 443.5 20.0 9.3e-133 443.0 20.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family IBV_3C PF03620.13 RUS80315.1 - 0.027 15.0 0.4 0.027 15.0 0.4 3.0 4 0 0 4 4 4 0 IBV 3C protein Luteo_Vpg PF01659.16 RUS80316.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein TMEM131_like PF12371.8 RUS80317.1 - 1.7e-23 82.7 14.1 4.4e-22 78.1 0.1 5.9 7 0 0 7 7 7 2 Transmembrane protein 131-like ASH PF15780.5 RUS80317.1 - 8.9e-15 54.7 2.3 0.00045 20.4 0.0 6.8 7 0 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RUS80317.1 - 1.3e-07 31.6 1.8 1.4 9.0 0.0 7.0 8 0 0 8 8 8 2 Protein of unknown function (DUF1573) Branch PF02485.21 RUS80318.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 RUS80319.1 - 5.5e-26 91.6 0.1 8.1e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme ApeC PF16977.5 RUS80320.1 - 2.9e-41 141.7 4.9 4.9e-41 140.9 4.9 1.4 1 0 0 1 1 1 1 C-terminal domain of apextrin MDH PF02315.16 RUS80321.1 - 0.00016 21.7 0.5 0.64 10.1 0.1 2.2 2 0 0 2 2 2 2 Methanol dehydrogenase beta subunit TM_PBP2_N PF16296.5 RUS80321.1 - 0.21 11.7 0.3 20 5.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters DUF4148 PF13663.6 RUS80321.1 - 0.23 11.7 1.3 10 6.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) RNA_replicase_B PF03431.13 RUS80321.1 - 0.29 9.5 0.3 7.5 4.9 0.0 2.0 1 1 1 2 2 2 0 RNA replicase, beta-chain Plasmod_dom_1 PF09715.10 RUS80321.1 - 0.38 10.8 1.6 2.4 8.3 0.1 2.2 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) 7tm_1 PF00001.21 RUS80322.1 - 6.1e-27 94.6 9.1 7.5e-27 94.3 9.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS80322.1 - 5.3e-08 32.8 12.9 7.1e-08 32.4 12.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS80322.1 - 0.0019 17.7 12.2 0.0046 16.4 12.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS80322.1 - 0.0036 17.1 8.6 0.0073 16.1 8.6 1.6 1 1 0 1 1 1 1 Olfactory receptor Srg PF02118.21 RUS80322.1 - 0.0055 16.4 5.9 0.0055 16.4 5.9 1.7 2 0 0 2 2 2 1 Srg family chemoreceptor FHA PF00498.26 RUS80323.1 - 9.4e-15 54.7 0.2 1.7e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 FHA domain DDE_Tnp_4 PF13359.6 RUS80324.1 - 6.4e-28 97.4 0.0 1e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS80324.1 - 7e-07 29.1 0.0 0.0022 17.6 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS80324.1 - 0.023 14.4 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain RIH_assoc PF08454.11 RUS80324.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated Cu-oxidase_2 PF07731.14 RUS80325.1 - 5.1e-35 120.2 1.1 2.1e-30 105.3 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RUS80325.1 - 5.4e-31 107.1 2.2 9.7e-30 103.0 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 RUS80325.1 - 6.7e-30 104.3 0.0 2.1e-29 102.7 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase CARD PF00619.21 RUS80326.1 - 9.3e-05 22.4 0.2 0.00025 21.0 0.2 1.8 1 0 0 1 1 1 1 Caspase recruitment domain DUF2570 PF10828.8 RUS80326.1 - 0.061 13.1 1.5 0.098 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) LAP2alpha PF11560.8 RUS80326.1 - 0.067 12.6 0.1 0.085 12.3 0.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha DUF4837 PF16125.5 RUS80326.1 - 0.11 11.6 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Sugar_tr PF00083.24 RUS80327.1 - 3.1e-23 82.4 2.7 3.1e-23 82.4 2.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS80327.1 - 1.7e-10 40.3 18.8 5.4e-09 35.4 14.6 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily Asp_protease_2 PF13650.6 RUS80327.1 - 8.3e-05 23.2 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS80327.1 - 0.0009 19.8 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 RUS80327.1 - 0.0046 16.7 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 RUS80327.1 - 0.16 11.8 0.1 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease HEAT_EZ PF13513.6 RUS80329.1 - 4.9e-33 113.1 3.5 4e-13 49.5 0.0 11.5 9 3 4 13 13 13 6 HEAT-like repeat HEAT PF02985.22 RUS80329.1 - 6.6e-30 100.6 6.1 0.0026 17.9 0.0 11.1 11 0 0 11 11 11 6 HEAT repeat Arm PF00514.23 RUS80329.1 - 1.6e-20 72.4 0.7 0.0011 18.9 0.0 9.0 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS80329.1 - 3.2e-19 69.1 0.0 0.0013 19.1 0.0 7.6 6 1 2 8 8 8 5 HEAT repeats Cnd1 PF12717.7 RUS80329.1 - 1.8e-16 60.6 0.2 0.0054 16.8 0.0 4.6 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 RUS80329.1 - 3.2e-14 52.6 0.0 1.5e-13 50.5 0.0 2.3 2 0 0 2 2 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 RUS80329.1 - 7.9e-13 48.8 1.0 0.21 12.2 0.0 6.6 5 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 RUS80329.1 - 1.1e-07 30.9 3.2 0.076 11.6 0.1 4.8 3 2 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 RUS80329.1 - 1.4e-05 24.7 1.0 3.1 7.3 0.0 5.5 3 2 2 5 5 5 2 CLASP N terminal MMS19_C PF12460.8 RUS80329.1 - 4.6e-05 22.7 0.0 2 7.4 0.0 4.1 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 RUS80329.1 - 0.0019 18.4 0.6 0.46 10.7 0.1 4.3 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 RUS80329.1 - 0.0022 18.0 1.1 0.016 15.2 0.2 2.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 RUS80329.1 - 0.11 11.5 0.1 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 Dopey, N-terminal Cnd3 PF12719.7 RUS80329.1 - 0.12 11.6 0.5 1.1 8.4 0.2 2.7 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CRM1_repeat_3 PF18787.1 RUS80329.1 - 0.15 12.2 0.1 0.6 10.3 0.1 2.0 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 CCM2_C PF16545.5 RUS80330.1 - 7.5e-20 71.3 0.3 6.3e-19 68.4 0.2 2.3 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology PID PF00640.23 RUS80330.1 - 0.004 17.2 0.1 0.006 16.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PRP38 PF03371.15 RUS80331.1 - 8.8e-61 204.8 0.8 1.2e-60 204.4 0.8 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 RUS80331.1 - 0.014 16.0 34.0 0.014 16.0 34.0 3.0 1 1 2 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GDA1_CD39 PF01150.17 RUS80331.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF5370 PF17340.2 RUS80331.1 - 0.17 11.8 0.3 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5370) AAA PF00004.29 RUS80333.1 - 2e-18 67.1 0.0 3.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 RUS80333.1 - 4.4e-15 55.4 0.0 1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 RUS80333.1 - 3.5e-11 43.1 1.5 6.3e-11 42.3 0.4 2.0 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 RUS80333.1 - 3.9e-11 43.6 0.0 2.4e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS80333.1 - 6.2e-11 42.7 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS80333.1 - 1.7e-05 25.2 0.2 3e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS80333.1 - 3.6e-05 23.6 0.0 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RUS80333.1 - 0.00041 19.8 0.0 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein DUF2075 PF09848.9 RUS80333.1 - 0.00075 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RUS80333.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 RUS80333.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RUS80333.1 - 0.033 14.0 0.8 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RUS80333.1 - 0.062 13.8 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 RUS80333.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase ATPase_2 PF01637.18 RUS80333.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 RUS80333.1 - 0.12 12.3 0.2 0.25 11.2 0.2 1.7 1 1 0 1 1 1 0 NTPase MAP65_ASE1 PF03999.12 RUS80334.1 - 0.056 12.1 1.2 0.061 12.0 1.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TUDOR PF00567.24 RUS80335.1 - 2.6e-292 950.9 0.0 4.1e-27 94.6 0.0 12.5 12 0 0 12 12 12 12 Tudor domain DUF4537 PF15057.6 RUS80335.1 - 1.2e-15 57.6 2.1 0.0072 16.3 0.0 9.6 9 0 0 9 9 9 3 Domain of unknown function (DUF4537) SMN PF06003.12 RUS80335.1 - 1.4e-12 47.4 69.9 0.00051 19.4 0.1 13.4 14 1 1 15 15 15 8 Survival motor neuron protein (SMN) Agenet PF05641.12 RUS80335.1 - 9.6e-12 45.2 20.3 4.4 7.8 0.0 11.7 12 0 0 12 12 12 5 Agenet domain 53-BP1_Tudor PF09038.10 RUS80335.1 - 0.00023 21.1 1.9 1.7 8.6 0.0 5.9 6 0 0 6 6 6 1 Tumour suppressor p53-binding protein-1 Tudor Tudor_2 PF18104.1 RUS80335.1 - 0.058 13.1 0.0 0.59 9.9 0.0 2.9 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Myosin_N PF02736.19 RUS80335.1 - 9.2 6.2 12.3 18 5.3 0.2 6.3 6 0 0 6 6 6 0 Myosin N-terminal SH3-like domain zf-C2H2 PF00096.26 RUS80336.1 - 1.5e-13 50.4 29.2 8.5e-05 22.8 5.2 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS80336.1 - 5.3e-11 42.4 11.5 1.8e-07 31.3 2.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS80336.1 - 0.0027 18.4 3.5 0.0027 18.4 3.5 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger Spore_III_AF PF09581.10 RUS80337.1 - 0.037 14.0 0.6 0.037 14.0 0.6 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Agouti PF05039.12 RUS80337.1 - 5.1 7.9 7.3 3 8.6 3.4 2.6 2 0 0 2 2 2 0 Agouti protein fn3 PF00041.21 RUS80338.1 - 4e-31 107.2 3.6 6.9e-09 35.9 0.5 6.4 6 0 0 6 6 6 6 Fibronectin type III domain Interfer-bind PF09294.10 RUS80338.1 - 0.0038 17.5 0.1 3.8 7.9 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Cadherin PF00028.17 RUS80338.1 - 0.031 14.7 1.6 3.6 8.1 0.0 3.3 4 0 0 4 4 4 0 Cadherin domain PIH1 PF08190.12 RUS80339.1 - 1.5e-60 203.4 1.8 4.9e-60 201.8 1.2 2.1 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RUS80339.1 - 1.7e-30 105.3 0.4 5e-30 103.8 0.4 1.9 1 0 0 1 1 1 1 PIH1 CS-like domain PAP_central PF04928.17 RUS80340.1 - 6.9e-111 369.1 0.0 9.4e-111 368.7 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RUS80340.1 - 2e-28 99.2 1.7 8.9e-19 67.8 0.1 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 RUS80340.1 - 1.4e-11 44.5 0.0 3.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 RUS80340.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Seipin PF06775.14 RUS80341.1 - 1.7e-48 165.4 1.0 2.9e-48 164.6 1.0 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF4229 PF14012.6 RUS80341.1 - 0.66 10.1 9.8 0.07 13.2 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) YoqO PF14037.6 RUS80341.1 - 0.79 10.3 8.2 0.3 11.6 4.1 2.2 2 0 0 2 2 2 0 YoqO-like protein Myb_DNA-binding PF00249.31 RUS80343.1 - 1.8e-10 40.8 0.3 7.7e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS80343.1 - 2.7e-09 37.1 0.1 0.00025 21.2 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain L31 PF09784.9 RUS80343.1 - 0.3 11.5 4.2 0.71 10.3 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 zf-H2C2_2 PF13465.6 RUS80344.1 - 3.2e-71 232.8 142.5 5e-07 29.9 0.3 18.4 19 0 0 19 19 19 15 Zinc-finger double domain zf-C2H2 PF00096.26 RUS80344.1 - 6e-54 177.6 155.0 4.3e-06 26.9 3.0 18.3 19 0 0 19 19 19 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80344.1 - 4.5e-50 164.0 144.1 0.001 19.7 1.8 18.1 18 0 0 18 18 18 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS80344.1 - 2.5e-23 81.8 111.1 0.00036 20.7 5.5 16.7 16 1 1 17 17 17 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS80344.1 - 1.4e-13 50.7 112.2 0.002 18.5 0.4 15.3 16 0 0 16 16 15 9 Zinc-finger of C2H2 type C1_1 PF00130.22 RUS80344.1 - 3.2e-09 36.5 73.7 0.013 15.4 1.7 12.2 4 3 5 11 11 11 8 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 RUS80344.1 - 9.5e-07 29.5 76.8 0.29 11.9 0.4 9.8 5 3 4 10 10 10 6 zinc-ribbon family zf-H2C2_5 PF13909.6 RUS80344.1 - 6.4e-06 25.8 3.8 6.4e-06 25.8 3.8 19.8 19 6 0 19 19 19 2 C2H2-type zinc-finger domain zf_UBZ PF18439.1 RUS80344.1 - 0.00013 21.5 82.3 0.053 13.1 0.4 15.9 16 1 1 17 17 16 4 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 RUS80344.1 - 0.0015 18.2 87.8 0.085 12.6 3.5 14.1 17 0 0 17 17 15 6 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS80344.1 - 0.0017 18.3 144.6 0.0093 15.9 1.4 17.0 19 0 0 19 19 18 10 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS80344.1 - 0.0031 17.8 7.8 0.0031 17.8 7.8 9.1 2 2 6 8 8 8 3 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 RUS80344.1 - 0.007 16.5 93.5 0.16 12.1 4.4 13.5 9 3 4 13 13 13 5 Zinc ribbon domain zf-C2HC_2 PF13913.6 RUS80344.1 - 0.067 13.1 0.1 0.067 13.1 0.1 13.9 15 0 0 15 15 14 0 zinc-finger of a C2HC-type HypA PF01155.19 RUS80344.1 - 0.19 11.8 69.7 0.2 11.7 1.6 9.4 2 2 8 10 10 10 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IL13 PF03487.13 RUS80344.1 - 1.1 9.1 6.5 3 7.7 0.2 3.5 3 1 0 3 3 3 0 Interleukin-13 zf_C2H2_13 PF18508.1 RUS80344.1 - 1.2 8.8 25.6 5.3 6.7 0.2 8.2 8 1 0 8 8 8 0 Zinc finger domain DHHC PF01529.20 RUS80345.1 - 5.9e-36 123.5 9.6 5.9e-36 123.5 9.6 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RUS80345.1 - 1.8e-33 115.0 0.2 2.8e-12 47.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS80345.1 - 1e-29 102.5 2.8 3.8e-08 33.7 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS80345.1 - 1.1e-26 89.9 0.5 1.2e-05 25.3 0.1 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 RUS80345.1 - 9e-24 82.8 1.5 0.0029 18.0 0.5 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 RUS80345.1 - 1.1e-22 79.7 3.4 2.3e-05 24.6 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DAZAP2 PF11029.8 RUS80345.1 - 0.084 13.8 0.4 0.16 12.9 0.4 1.4 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Sugar_tr PF00083.24 RUS80346.1 - 1.6e-38 132.8 12.8 1.6e-38 132.8 12.8 1.4 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS80346.1 - 4.1e-18 65.4 23.7 4.1e-18 65.4 23.7 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily YqgB PF11036.8 RUS80346.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Virulence promoting factor Aa_trans PF01490.18 RUS80347.1 - 2.4e-55 187.9 25.6 2.8e-55 187.7 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RabGAP-TBC PF00566.18 RUS80348.1 - 9.9e-36 123.4 1.1 1.1e-35 123.3 1.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PID PF00640.23 RUS80350.1 - 3.1e-05 24.0 0.9 7.2e-05 22.8 0.3 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) F-box-like PF12937.7 RUS80351.1 - 3.5e-06 26.8 0.8 1.7e-05 24.6 0.8 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS80351.1 - 0.04 13.8 1.8 0.097 12.6 0.1 2.6 3 0 0 3 3 3 0 F-box domain F-box_4 PF15966.5 RUS80351.1 - 0.094 12.6 4.1 0.45 10.4 0.7 3.0 2 1 0 2 2 2 0 F-box NHL PF01436.21 RUS80352.1 - 7.7e-06 25.7 0.1 0.00022 21.1 0.2 2.5 2 0 0 2 2 2 1 NHL repeat zf-RING_5 PF14634.6 RUS80352.1 - 5.5e-05 23.0 7.4 5.5e-05 23.0 7.4 4.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS80352.1 - 0.00047 20.0 9.7 0.00047 20.0 9.7 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 RUS80352.1 - 0.00078 19.5 3.5 0.00078 19.5 3.5 5.2 5 1 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS80352.1 - 0.002 18.1 5.2 0.002 18.1 5.2 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS80352.1 - 0.0089 15.9 8.9 0.0089 15.9 8.9 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) YcaO_C PF18381.1 RUS80352.1 - 0.024 14.5 0.3 0.21 11.5 0.2 2.2 2 0 0 2 2 2 0 YcaO cyclodehydratase C-terminal domain Mit_KHE1 PF10173.9 RUS80352.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Sld5 PF05916.11 RUS80353.1 - 3.6e-06 27.4 0.7 7.6e-06 26.4 0.7 1.6 1 1 0 1 1 1 1 GINS complex protein PHR PF08005.12 RUS80354.1 - 7.6e-44 150.0 0.8 1.3e-43 149.3 0.8 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 RUS80354.1 - 2.8e-22 79.1 0.0 1e-21 77.3 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS80354.1 - 9e-09 35.4 1.6 4.2e-08 33.2 0.4 2.5 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 RUS80354.1 - 0.026 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) BBS2_Mid PF14783.6 RUS80355.1 - 0.00012 22.0 1.3 2.9 8.0 0.2 4.7 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 RUS80355.1 - 0.0097 16.8 3.1 1.2 10.1 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat PHTB1_N PF14727.6 RUS80355.1 - 0.057 12.8 0.2 1.5 8.1 0.0 2.8 2 1 2 4 4 4 0 PTHB1 N-terminus VCBS PF13517.6 RUS80355.1 - 0.088 13.4 0.0 0.51 11.0 0.1 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Arf PF00025.21 RUS80356.1 - 5.9e-74 247.3 0.4 6.7e-74 247.1 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RUS80356.1 - 7.1e-13 48.4 1.9 7.4e-07 28.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 RUS80356.1 - 8.1e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS80356.1 - 1.2e-10 41.2 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS80356.1 - 4.6e-10 39.2 0.0 6.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RUS80356.1 - 3.8e-09 36.2 0.0 4.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS80356.1 - 4.7e-06 26.7 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2025 PF09634.10 RUS80356.1 - 0.017 15.2 0.0 0.04 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) TniB PF05621.11 RUS80356.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 RUS80357.1 - 5.5e-32 111.2 0.0 1e-26 93.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 RUS80357.1 - 7.5e-13 48.3 0.1 1.6e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 RUS80357.1 - 4.6e-11 42.7 0.5 1.3e-10 41.2 0.5 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 RUS80357.1 - 1.3e-06 28.0 0.0 3.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 RUS80357.1 - 2.4e-06 27.0 0.0 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 RUS80357.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 RUS80357.1 - 0.15 11.4 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-B_box PF00643.24 RUS80358.1 - 1.2e-10 41.3 22.4 8.5e-09 35.4 4.3 3.0 3 0 0 3 3 3 2 B-box zinc finger fn3 PF00041.21 RUS80358.1 - 0.00017 21.9 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain YtxH PF12732.7 RUS80358.1 - 0.2 12.2 0.7 0.45 11.1 0.7 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF1664 PF07889.12 RUS80358.1 - 0.25 11.4 1.4 1.3 9.1 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 RUS80358.1 - 0.26 11.1 2.9 0.21 11.4 1.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LOH1CR12 PF10158.9 RUS80358.1 - 0.44 10.6 3.0 15 5.6 0.1 2.3 1 1 1 2 2 2 0 Tumour suppressor protein TMPIT PF07851.13 RUS80358.1 - 0.83 8.8 3.5 1.2 8.3 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF5082 PF16888.5 RUS80358.1 - 1.7 8.9 4.8 4.9 7.5 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Globin PF00042.22 RUS80359.1 - 2.1e-20 73.3 0.8 2.9e-20 72.9 0.8 1.2 1 0 0 1 1 1 1 Globin Cornichon PF03311.14 RUS80360.1 - 4.1e-50 169.2 6.1 5e-50 168.9 6.1 1.0 1 0 0 1 1 1 1 Cornichon protein DUF3671 PF12420.8 RUS80360.1 - 0.0017 18.4 0.8 0.0017 18.4 0.8 2.2 1 1 1 2 2 2 1 Protein of unknown function DUF2976 PF11190.8 RUS80360.1 - 1.5 8.7 5.0 6 6.7 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) AAA_11 PF13086.6 RUS80361.1 - 0.0093 15.8 11.4 0.01 15.7 11.4 1.3 1 0 0 1 1 1 1 AAA domain DUF4228 PF14009.6 RUS80361.1 - 0.024 15.0 8.1 0.029 14.8 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) FGF-BP1 PF06473.12 RUS80361.1 - 0.027 14.3 21.1 0.043 13.6 21.1 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CENP-N PF05238.13 RUS80361.1 - 0.035 13.4 22.2 0.046 13.0 22.0 1.3 1 1 0 1 1 1 0 Kinetochore protein CHL4 like Neuregulin PF02158.15 RUS80361.1 - 0.039 13.3 5.3 0.045 13.1 5.3 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region Nop14 PF04147.12 RUS80361.1 - 0.11 10.7 57.7 0.15 10.3 57.7 1.1 1 0 0 1 1 1 0 Nop14-like family Red1 PF07964.11 RUS80361.1 - 0.17 10.1 33.0 0.2 9.9 33.0 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Endostatin PF06482.11 RUS80361.1 - 0.23 10.9 7.9 0.29 10.5 7.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin AF-4 PF05110.13 RUS80361.1 - 0.29 9.2 29.7 0.33 9.0 29.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RPOL_N PF14700.6 RUS80361.1 - 0.44 9.9 20.5 0.59 9.5 20.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Membralin PF09746.9 RUS80361.1 - 1.3 8.0 12.1 1.6 7.7 12.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein GAGA_bind PF06217.12 RUS80361.1 - 1.3 9.2 26.6 2.3 8.4 26.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family EOS1 PF12326.8 RUS80361.1 - 1.4 8.9 11.5 2.2 8.2 11.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF3405 PF11885.8 RUS80361.1 - 2.6 6.6 14.0 4.1 5.9 14.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF1943 PF09172.11 RUS80361.1 - 3.2 6.9 15.6 4.8 6.3 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2828 PF11443.8 RUS80361.1 - 3.3 5.7 25.5 4.8 5.2 25.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4569 PF15133.6 RUS80361.1 - 3.5 7.3 14.5 4.5 6.9 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Otopetrin PF03189.13 RUS80361.1 - 4.3 6.0 7.8 5 5.8 7.8 1.1 1 0 0 1 1 1 0 Otopetrin RNA_pol_Rpc4 PF05132.14 RUS80361.1 - 4.4 7.7 35.1 1.1 9.7 24.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Band_3_cyto PF07565.13 RUS80361.1 - 5.1 6.8 12.6 6.4 6.5 12.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Kei1 PF08552.11 RUS80361.1 - 5.4 6.8 4.9 7.3 6.4 4.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MDM10 PF12519.8 RUS80361.1 - 6.7 5.5 21.3 8.3 5.2 21.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TMEM214 PF10151.9 RUS80361.1 - 7.1 5.0 27.4 11 4.4 27.4 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator ALMT PF11744.8 RUS80361.1 - 7.1 5.3 16.9 9.1 5.0 16.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4551 PF15087.6 RUS80361.1 - 7.2 5.3 13.9 8.7 5.0 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.16 RUS80361.1 - 7.4 6.6 16.0 9.8 6.2 16.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hydin_ADK PF17213.3 RUS80361.1 - 9.2 6.5 10.3 13 6.1 10.3 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_21 PF13304.6 RUS80361.1 - 9.7 5.9 17.7 14 5.4 17.7 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Calx-beta PF03160.14 RUS80362.1 - 1.1e-51 173.2 10.3 3.2e-31 107.5 1.8 2.6 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex_C PF16494.5 RUS80362.1 - 8.2e-37 126.5 2.4 1.3e-36 125.9 2.4 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Na_Ca_ex PF01699.24 RUS80362.1 - 1.1e-28 100.1 10.6 1.7e-28 99.5 10.6 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein OSK PF17182.4 RUS80362.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 OSK domain BUD22 PF09073.10 RUS80363.1 - 4.6e-07 29.5 20.4 5.5e-07 29.3 20.4 1.0 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RUS80363.1 - 3.5e-06 25.6 9.2 3.7e-06 25.5 9.2 1.1 1 0 0 1 1 1 1 Nop14-like family BSP_II PF05432.11 RUS80363.1 - 5e-05 23.1 20.7 6.8e-05 22.7 20.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4746 PF15928.5 RUS80363.1 - 0.00011 21.8 20.9 0.00013 21.5 20.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) GEMIN8 PF15348.6 RUS80363.1 - 0.00017 22.0 6.6 0.0002 21.8 6.6 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 DUF913 PF06025.12 RUS80363.1 - 0.00021 20.4 4.7 0.00023 20.3 4.7 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 RUS80363.1 - 0.00021 21.1 25.8 0.0003 20.6 25.8 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 RUS80363.1 - 0.00063 18.7 8.3 0.00078 18.4 8.3 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 DUF2201_N PF13203.6 RUS80363.1 - 0.0008 19.1 2.0 0.0008 19.1 2.0 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain RNA_pol_3_Rpc31 PF11705.8 RUS80363.1 - 0.00093 19.5 30.5 0.0013 19.1 30.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.22 RUS80363.1 - 0.001 18.4 4.7 0.0012 18.2 4.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Serinc PF03348.15 RUS80363.1 - 0.0011 18.0 1.2 0.0015 17.6 1.2 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) DDHD PF02862.17 RUS80363.1 - 0.0012 19.0 1.4 0.0013 18.9 1.4 1.2 1 0 0 1 1 1 1 DDHD domain CSRNP_N PF16019.5 RUS80363.1 - 0.0015 18.5 7.8 0.0022 17.9 7.8 1.2 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus DUF4471 PF14740.6 RUS80363.1 - 0.0019 17.5 3.8 0.0025 17.1 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) FAM60A PF15396.6 RUS80363.1 - 0.0023 18.0 12.3 0.0028 17.7 12.3 1.2 1 0 0 1 1 1 1 Protein Family FAM60A AAA_11 PF13086.6 RUS80363.1 - 0.0025 17.7 7.5 0.0028 17.5 7.5 1.1 1 0 0 1 1 1 1 AAA domain CDC27 PF09507.10 RUS80363.1 - 0.0026 17.2 25.8 0.0034 16.9 25.8 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SAPS PF04499.15 RUS80363.1 - 0.0027 16.6 4.9 0.0029 16.5 4.9 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Endostatin PF06482.11 RUS80363.1 - 0.0029 17.1 2.3 0.0035 16.9 2.3 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 RUS80363.1 - 0.0038 15.7 0.7 0.0041 15.6 0.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 BORG_CEP PF14957.6 RUS80363.1 - 0.0046 18.1 5.1 0.0064 17.6 5.1 1.3 1 0 0 1 1 1 1 Cdc42 effector Rrn6 PF10214.9 RUS80363.1 - 0.0054 15.3 4.4 0.0063 15.1 4.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spore_coat_CotO PF14153.6 RUS80363.1 - 0.0073 16.3 18.9 0.0095 15.9 18.9 1.1 1 0 0 1 1 1 1 Spore coat protein CotO CAC1F_C PF16885.5 RUS80363.1 - 0.0088 15.7 7.4 0.011 15.4 7.4 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term DUF4228 PF14009.6 RUS80363.1 - 0.0089 16.4 3.6 0.01 16.2 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) DDRGK PF09756.9 RUS80363.1 - 0.011 15.3 34.7 0.014 15.0 34.7 1.1 1 0 0 1 1 1 0 DDRGK domain ALMT PF11744.8 RUS80363.1 - 0.015 14.2 4.7 0.015 14.2 4.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GAGA_bind PF06217.12 RUS80363.1 - 0.015 15.6 13.4 0.019 15.3 13.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RAB3GAP2_C PF14656.6 RUS80363.1 - 0.015 13.5 3.0 0.02 13.1 3.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RXT2_N PF08595.11 RUS80363.1 - 0.017 15.2 13.2 0.029 14.4 13.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SR-25 PF10500.9 RUS80363.1 - 0.018 14.7 34.2 0.028 14.0 34.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Roughex PF06020.11 RUS80363.1 - 0.02 14.0 3.1 0.023 13.8 3.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RNA_pol_Rpc4 PF05132.14 RUS80363.1 - 0.022 15.2 16.5 0.035 14.5 16.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 RUS80363.1 - 0.022 14.2 14.9 0.027 13.9 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2151 PF10221.9 RUS80363.1 - 0.026 13.1 15.5 0.032 12.8 15.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FYDLN_acid PF09538.10 RUS80363.1 - 0.03 15.0 18.1 0.055 14.2 18.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cellulose_synt PF03552.14 RUS80363.1 - 0.033 12.7 8.3 0.039 12.5 8.3 1.0 1 0 0 1 1 1 0 Cellulose synthase CENP-N PF05238.13 RUS80363.1 - 0.035 13.4 12.8 0.043 13.1 12.8 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PPP4R2 PF09184.11 RUS80363.1 - 0.035 13.7 21.5 0.044 13.4 21.5 1.1 1 0 0 1 1 1 0 PPP4R2 FemAB PF02388.16 RUS80363.1 - 0.038 12.9 11.5 0.044 12.6 11.5 1.1 1 0 0 1 1 1 0 FemAB family MMU163 PF17119.5 RUS80363.1 - 0.04 13.1 5.3 0.057 12.6 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis RR_TM4-6 PF06459.12 RUS80363.1 - 0.053 13.3 23.1 0.068 13.0 23.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 RUS80363.1 - 0.056 12.6 10.9 0.083 12.1 10.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.13 RUS80363.1 - 0.073 11.9 21.3 0.11 11.3 21.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 RUS80363.1 - 0.079 13.3 30.8 0.11 12.8 30.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CAF1 PF04857.20 RUS80363.1 - 0.079 12.1 8.7 0.096 11.8 8.7 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF2126 PF09899.9 RUS80363.1 - 0.084 10.9 3.0 0.089 10.8 3.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RPOL_N PF14700.6 RUS80363.1 - 0.092 12.1 17.4 0.12 11.8 17.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal AF-4 PF05110.13 RUS80363.1 - 0.096 10.8 18.7 0.11 10.6 18.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SLC12 PF03522.15 RUS80363.1 - 0.13 11.3 11.3 0.15 11.1 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3807 PF12720.7 RUS80363.1 - 0.13 12.5 20.0 0.21 11.9 20.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF935 PF06074.12 RUS80363.1 - 0.16 10.7 6.5 0.19 10.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Presenilin PF01080.17 RUS80363.1 - 0.17 10.6 14.7 0.23 10.2 14.7 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 RUS80363.1 - 0.36 10.8 1.6 0.56 10.1 1.6 1.5 1 0 0 1 1 1 0 N-glycosylation protein Hid1 PF12722.7 RUS80363.1 - 0.39 8.8 8.7 0.41 8.7 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Astro_capsid_p PF12226.8 RUS80363.1 - 0.41 9.7 10.3 0.55 9.3 10.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RPN2_C PF18004.1 RUS80363.1 - 0.42 10.5 34.9 0.63 9.9 34.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Peptidase_S64 PF08192.11 RUS80363.1 - 0.5 8.8 9.9 0.74 8.2 9.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 VIR_N PF15912.5 RUS80363.1 - 0.53 9.8 15.3 0.72 9.4 15.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Otopetrin PF03189.13 RUS80363.1 - 0.61 8.8 2.7 0.73 8.6 2.7 1.1 1 0 0 1 1 1 0 Otopetrin DUF4820 PF16091.5 RUS80363.1 - 0.67 9.3 15.2 1.1 8.6 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 RUS80363.1 - 0.67 9.7 16.9 1.2 8.9 16.9 1.5 1 0 0 1 1 1 0 Connexin FancD2 PF14631.6 RUS80363.1 - 0.71 7.2 20.8 0.9 6.9 20.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease OATP PF03137.20 RUS80363.1 - 0.75 8.0 7.9 1 7.5 7.9 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 RUS80363.1 - 0.76 9.8 7.6 1 9.4 7.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2058 PF09831.9 RUS80363.1 - 0.76 9.9 19.9 1.1 9.3 19.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) V_ATPase_I PF01496.19 RUS80363.1 - 0.81 7.5 20.3 1.1 7.1 20.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPL5 PF18168.1 RUS80363.1 - 0.83 8.9 17.1 1.2 8.4 17.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Neur_chan_memb PF02932.16 RUS80363.1 - 1 9.3 9.3 1.4 9.0 9.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1168 PF06658.12 RUS80363.1 - 1.1 9.1 44.2 1.5 8.6 44.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Rtf2 PF04641.12 RUS80363.1 - 1.1 8.6 28.8 1.7 8.0 28.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Afi1 PF07792.12 RUS80363.1 - 1.1 9.7 19.3 1.7 9.2 19.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Band_3_cyto PF07565.13 RUS80363.1 - 1.2 8.9 7.7 1.7 8.4 7.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paramyxo_ncap PF00973.19 RUS80363.1 - 1.3 7.9 10.9 1.6 7.6 10.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FGF-BP1 PF06473.12 RUS80363.1 - 1.3 8.8 25.2 2 8.2 25.2 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) eIF3_subunit PF08597.10 RUS80363.1 - 1.3 8.9 47.7 2.2 8.1 47.7 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tfb4 PF03850.14 RUS80363.1 - 1.3 8.4 3.7 1.6 8.2 3.7 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 MIF4G_like_2 PF09090.11 RUS80363.1 - 1.4 8.3 12.4 1.8 8.0 12.4 1.1 1 0 0 1 1 1 0 MIF4G like DUF4366 PF14283.6 RUS80363.1 - 1.6 8.8 15.3 2.4 8.2 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF789 PF05623.12 RUS80363.1 - 1.6 8.3 8.0 2.2 7.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Gti1_Pac2 PF09729.9 RUS80363.1 - 1.6 8.7 16.7 2.4 8.2 16.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family RP-C_C PF11800.8 RUS80363.1 - 2.6 8.1 11.3 3.4 7.7 11.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Adeno_terminal PF02459.15 RUS80363.1 - 2.6 6.3 7.2 3.2 6.1 7.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF5427 PF10310.9 RUS80363.1 - 2.9 6.8 24.8 3.7 6.4 24.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PA26 PF04636.13 RUS80363.1 - 3.5 6.4 11.5 4.5 6.1 11.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CLN3 PF02487.17 RUS80363.1 - 4 6.4 11.7 5.8 5.9 11.7 1.1 1 0 0 1 1 1 0 CLN3 protein MCM_bind PF09739.9 RUS80363.1 - 5.5 5.3 17.4 7.1 5.0 17.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Tim54 PF11711.8 RUS80363.1 - 5.6 5.6 25.4 7.9 5.2 25.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 RUS80363.1 - 5.8 5.7 32.1 7.8 5.3 32.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Red1 PF07964.11 RUS80363.1 - 5.9 5.0 28.0 7.6 4.6 28.0 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Slu7 PF11708.8 RUS80363.1 - 5.9 6.6 27.8 8 6.1 27.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Membralin PF09746.9 RUS80363.1 - 6.9 5.6 9.2 8.7 5.3 9.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein AAA_23 PF13476.6 RUS80363.1 - 7.3 7.0 27.5 10 6.6 27.5 1.1 1 0 0 1 1 1 0 AAA domain XRN_M PF17846.1 RUS80363.1 - 9 5.1 12.6 12 4.7 12.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Ldl_recept_a PF00057.18 RUS80364.1 - 1.2e-05 25.4 4.9 2.5e-05 24.4 4.9 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 RUS80364.1 - 0.045 13.5 1.4 0.14 12.0 1.4 1.8 1 0 0 1 1 1 0 Glucosidase II beta subunit-like ANAPC4_WD40 PF12894.7 RUS80365.1 - 1.8e-12 47.4 0.2 0.0073 16.6 0.0 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS80365.1 - 1.3e-09 38.5 14.8 0.5 11.3 0.0 9.2 10 0 0 10 10 10 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 RUS80365.1 - 1.2e-05 24.4 0.9 0.009 15.0 0.0 3.8 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS80365.1 - 0.0018 18.2 0.1 3.7 7.4 0.1 3.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 RUS80365.1 - 0.014 14.4 0.4 1.7 7.4 0.0 3.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain CBM_20 PF00686.19 RUS80365.1 - 0.16 11.9 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 Starch binding domain Frtz PF11768.8 RUS80365.1 - 0.16 10.2 0.1 2.8 6.1 0.0 2.5 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ctf8 PF09696.10 RUS80366.1 - 1.5e-14 54.5 0.1 2.2e-12 47.5 0.0 2.2 1 1 1 2 2 2 2 Ctf8 NICE-3 PF07406.11 RUS80370.1 - 3.7e-49 167.2 0.1 4.7e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 NICE-3 protein ApeC PF16977.5 RUS80371.1 - 2e-45 155.3 0.9 3.1e-45 154.6 0.9 1.3 1 0 0 1 1 1 1 C-terminal domain of apextrin Astacin PF01400.24 RUS80371.1 - 4e-25 88.5 0.4 2.8e-24 85.8 0.0 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.20 RUS80371.1 - 1.4e-06 28.6 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 CUB domain Kringle PF00051.18 RUS80371.1 - 5.3e-06 26.7 0.2 2e-05 24.8 0.2 2.0 1 0 0 1 1 1 1 Kringle domain Ntox15 PF15604.6 RUS80371.1 - 0.0068 16.5 2.3 2.9 8.0 0.2 2.4 2 0 0 2 2 2 2 Novel toxin 15 BSMAP PF12280.8 RUS80371.1 - 0.0095 16.2 0.1 5.9 7.1 0.0 2.4 2 0 0 2 2 2 2 Brain specific membrane anchored protein SLATT_4 PF18186.1 RUS80371.1 - 0.15 11.7 0.3 9.9 5.8 0.0 3.2 3 1 1 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 4 Mab-21 PF03281.14 RUS80372.1 - 7.4e-11 41.9 0.1 8.2e-10 38.4 0.1 2.1 1 1 0 1 1 1 1 Mab-21 protein DUF2061 PF09834.9 RUS80373.1 - 2.5 8.7 19.2 29 5.3 2.3 4.4 1 1 4 5 5 5 0 Predicted membrane protein (DUF2061) Calx-beta PF03160.14 RUS80374.1 - 9.9e-34 115.5 8.1 3e-08 33.7 0.0 8.5 9 0 0 9 9 9 5 Calx-beta domain GPS PF01825.21 RUS80374.1 - 0.0046 17.4 3.0 0.0096 16.4 3.0 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF1735 PF08522.10 RUS80374.1 - 0.053 14.1 1.1 17 6.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1735) Glyco_hydro_30C PF17189.4 RUS80374.1 - 0.064 13.5 0.0 5.1 7.4 0.0 3.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain DUF4843 PF16132.5 RUS80374.1 - 0.089 12.4 0.0 19 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) 7tm_2 PF00002.24 RUS80375.1 - 1.1e-17 64.1 20.1 1.7e-17 63.5 20.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4064 PF13273.6 RUS80375.1 - 1 9.7 16.2 0.046 14.0 1.8 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) Mid2 PF04478.12 RUS80375.1 - 2.5 7.9 4.4 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Abhydrolase_6 PF12697.7 RUS80376.1 - 0.00042 21.0 0.1 0.00092 19.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 RUS80376.1 - 0.0074 16.0 0.2 0.046 13.4 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 RUS80376.1 - 0.034 13.4 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sigma70_r2 PF04542.14 RUS80376.1 - 0.093 12.5 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-70 region 2 Abhydrolase_1 PF00561.20 RUS80376.1 - 0.12 12.0 1.3 0.64 9.6 0.1 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold Cutinase PF01083.22 RUS80376.1 - 0.21 11.5 0.1 26 4.7 0.0 2.6 2 1 0 2 2 2 0 Cutinase ribosomal_L24 PF17136.4 RUS80377.1 - 3.9e-09 36.8 0.0 1.1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 RUS80377.1 - 0.012 15.5 0.3 0.028 14.4 0.1 1.7 2 0 0 2 2 2 0 KOW motif DUF1441 PF07278.11 RUS80377.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) G-patch PF01585.23 RUS80378.1 - 4.9e-11 42.3 4.0 1.6e-10 40.7 4.0 1.9 1 0 0 1 1 1 1 G-patch domain Surp PF01805.20 RUS80378.1 - 5.6e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Surp module G-patch_2 PF12656.7 RUS80378.1 - 0.0086 16.2 0.2 0.035 14.2 0.2 2.1 1 0 0 1 1 1 1 G-patch domain FCSD-flav_bind PF09242.11 RUS80378.1 - 0.17 12.3 0.1 0.52 10.7 0.1 1.9 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding TMF_TATA_bd PF12325.8 RUS80379.1 - 1.5e-32 112.2 16.8 1.5e-32 112.2 16.8 5.2 2 1 3 5 5 5 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 RUS80379.1 - 0.0014 18.9 10.6 0.0014 18.9 10.6 3.8 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) GAS PF13851.6 RUS80379.1 - 0.0029 17.0 12.7 0.0029 17.0 12.7 4.4 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding PilW PF16074.5 RUS80379.1 - 0.003 17.6 0.1 0.0069 16.4 0.1 1.7 1 0 0 1 1 1 1 Type IV Pilus-assembly protein W HAP1_N PF04849.13 RUS80379.1 - 0.0054 16.0 13.0 0.0054 16.0 13.0 3.1 2 1 1 3 3 2 1 HAP1 N-terminal conserved region DUF5082 PF16888.5 RUS80379.1 - 0.0082 16.4 8.7 0.0082 16.4 8.7 5.1 3 2 0 3 3 3 1 Domain of unknown function (DUF5082) DivIC PF04977.15 RUS80379.1 - 0.023 14.4 1.4 0.023 14.4 1.4 7.1 3 3 4 8 8 8 0 Septum formation initiator CALCOCO1 PF07888.11 RUS80379.1 - 0.024 13.5 62.1 0.027 13.4 27.4 4.0 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 RUS80379.1 - 0.09 12.8 73.8 0.23 11.5 20.7 4.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 RUS80379.1 - 1.8 8.6 30.5 0.75 9.8 3.7 5.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 RUS80379.1 - 2.2 7.6 64.6 0.02 14.4 17.0 3.6 2 1 0 3 3 3 0 Golgin subfamily A member 5 HOOK PF05622.12 RUS80379.1 - 8.2 4.4 60.3 2.7 6.0 40.4 2.7 2 1 0 2 2 2 0 HOOK protein Cortex-I_coil PF09304.10 RUS80379.1 - 9.4 6.5 50.0 0.16 12.2 7.6 4.5 3 2 0 3 3 3 0 Cortexillin I, coiled coil Mt_ATP-synt_D PF05873.12 RUS80380.1 - 1.2e-34 119.4 3.6 1.4e-34 119.1 3.6 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) MRP-S26 PF14943.6 RUS80380.1 - 0.019 14.9 0.4 0.024 14.5 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4570 PF15134.6 RUS80380.1 - 0.069 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DDE_Tnp_1_7 PF13843.6 RUS80383.1 - 4.1e-06 26.3 0.0 7e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Transposase IS4 DUF2002 PF09400.10 RUS80384.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) Trypsin PF00089.26 RUS80386.1 - 4.7e-44 150.8 0.4 8.9e-44 149.9 0.2 1.6 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 RUS80386.1 - 1.6e-09 38.2 0.1 2.7e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) TFIIA_gamma_C PF02751.14 RUS80389.1 - 5.2e-36 122.5 9.9 1e-20 73.6 2.1 2.4 1 1 1 2 2 2 2 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 RUS80389.1 - 1.9e-07 30.9 0.1 3.3e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF4750 PF15938.5 RUS80389.1 - 0.044 13.5 1.2 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) Mak16 PF04874.14 RUS80389.1 - 0.046 14.3 0.0 0.6 10.7 0.0 2.0 1 1 1 2 2 2 0 Mak16 protein C-terminal region Thermopsin PF05317.11 RUS80389.1 - 0.18 11.2 1.1 8.3 5.8 0.2 2.1 1 1 1 2 2 2 0 Thermopsin Ion_trans PF00520.31 RUS80390.1 - 2e-19 69.8 14.3 2.9e-19 69.3 14.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS80390.1 - 9.7e-12 44.7 3.1 9.7e-12 44.7 3.1 2.5 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 RUS80390.1 - 1.4e-09 37.9 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sporozoite_P67 PF05642.11 RUS80391.1 - 0.16 10.0 0.0 0.18 9.9 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 RUS80392.1 - 0.66 9.5 48.5 2 8.0 28.9 2.3 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 RUS80392.1 - 0.91 9.9 19.9 0.55 10.6 7.1 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Presenilin PF01080.17 RUS80392.1 - 1.3 7.7 15.0 0.2 10.4 6.2 2.2 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 RUS80392.1 - 2.9 6.8 10.8 0.84 8.6 4.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Band_3_cyto PF07565.13 RUS80392.1 - 5 6.9 12.4 2.9 7.6 4.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.9 RUS80392.1 - 7.4 6.6 13.1 24 4.9 7.9 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4770 PF15994.5 RUS80392.1 - 8.9 6.5 26.8 2 8.6 15.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) zf-C3HC4_2 PF13923.6 RUS80395.1 - 1.6e-07 31.0 12.5 1.6e-07 31.0 12.5 3.9 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS80395.1 - 1.5e-06 28.1 12.7 1.5e-06 28.1 12.7 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS80395.1 - 2e-06 27.5 12.8 2e-06 27.5 12.8 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS80395.1 - 2e-05 24.8 12.1 2e-05 24.8 12.1 3.8 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 RUS80395.1 - 0.0001 22.4 12.4 0.0001 22.4 12.4 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RUS80395.1 - 0.00041 20.1 9.5 0.00041 20.1 9.5 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS80395.1 - 0.0031 17.4 11.1 0.0031 17.4 11.1 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RUS80395.1 - 0.0039 17.4 10.4 0.0039 17.4 10.4 3.3 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 RUS80395.1 - 0.0083 16.0 6.2 0.0083 16.0 6.2 2.3 4 0 0 4 4 1 1 zf-RING of BARD1-type protein DUF4407 PF14362.6 RUS80395.1 - 0.0088 15.4 0.6 0.011 15.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 RUS80395.1 - 0.011 16.1 0.4 0.13 12.8 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein U-box PF04564.15 RUS80395.1 - 0.016 15.4 0.0 0.13 12.4 0.0 2.5 3 0 0 3 3 3 0 U-box domain Lipoprotein_20 PF13942.6 RUS80395.1 - 0.019 14.9 4.1 0.033 14.1 4.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein zf-TRAF PF02176.18 RUS80395.1 - 0.037 14.7 4.2 0.037 14.7 4.2 3.3 2 1 1 3 3 2 0 TRAF-type zinc finger MSP1_C PF07462.11 RUS80395.1 - 0.048 12.3 0.1 0.059 12.1 0.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus FliMN_C PF01052.20 RUS80395.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Fzo_mitofusin PF04799.13 RUS80395.1 - 0.13 11.8 2.6 0.24 11.0 2.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF1640 PF07798.11 RUS80395.1 - 0.26 11.3 3.7 0.18 11.8 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) MbeD_MobD PF04899.12 RUS80395.1 - 0.3 11.2 4.5 2.8 8.1 1.7 3.2 3 1 0 3 3 3 0 MbeD/MobD like Baculo_PEP_C PF04513.12 RUS80395.1 - 0.45 10.6 1.8 1.4 9.0 0.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 RUS80395.1 - 1.5 7.6 5.8 2.3 7.0 5.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_10 PF16685.5 RUS80395.1 - 2.7 8.2 19.9 0.096 12.8 10.6 2.7 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF4200 PF13863.6 RUS80395.1 - 4.3 7.8 8.5 11 6.5 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.12 RUS80395.1 - 6.4 7.3 10.4 6.5 7.3 7.8 2.2 1 1 1 2 2 2 0 Cell division protein ZapB SAP PF02037.27 RUS80396.1 - 2.9e-07 30.1 1.9 2.9e-07 30.1 1.9 2.3 2 0 0 2 2 2 1 SAP domain UBX PF00789.20 RUS80397.1 - 4.5e-14 52.4 0.0 9.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 RUS80397.1 - 6.7e-14 51.8 0.1 1.3e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like GATA PF00320.27 RUS80398.1 - 5e-30 102.8 20.4 9.8e-16 57.1 5.6 2.8 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RUS80398.1 - 6.4e-05 22.4 9.6 0.032 13.7 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 RUS80398.1 - 0.024 14.7 1.8 2.9 8.1 0.1 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 RUS80398.1 - 0.053 13.8 10.1 0.52 10.6 2.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2387 PF09526.10 RUS80398.1 - 0.058 13.5 2.6 21 5.3 0.1 3.3 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Auto_anti-p27 PF06677.12 RUS80398.1 - 0.1 12.7 5.9 1.8 8.8 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 RUS80398.1 - 0.1 12.6 8.1 4.2 7.5 1.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 RUS80398.1 - 0.22 11.6 1.2 14 5.8 0.1 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.17 RUS80398.1 - 2.1 8.3 4.6 23 4.9 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_15 PF17032.5 RUS80398.1 - 4.2 8.2 5.4 11 6.9 0.6 2.7 1 1 1 2 2 2 0 zinc-ribbon family DUF2457 PF10446.9 RUS80400.1 - 0.00021 20.6 23.2 0.00022 20.5 23.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 RUS80400.1 - 0.054 13.1 11.9 0.064 12.8 11.9 1.1 1 0 0 1 1 1 0 PPP4R2 TFB6 PF17110.5 RUS80400.1 - 0.33 10.7 7.0 0.44 10.3 7.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 RUS80400.1 - 0.41 8.8 19.8 0.5 8.5 19.8 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS80400.1 - 0.88 8.9 15.3 1.4 8.3 15.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pes-10 PF07149.11 RUS80400.1 - 0.89 8.6 8.5 0.95 8.5 8.5 1.1 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 RUS80400.1 - 1.1 8.6 19.8 1.4 8.3 19.8 1.1 1 0 0 1 1 1 0 SDA1 CNDH2_C PF16858.5 RUS80400.1 - 1.3 8.8 7.7 1.6 8.5 7.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFIIA PF03153.13 RUS80400.1 - 1.4 8.8 18.4 1.4 8.8 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RUS80400.1 - 3.9 6.7 16.5 4.8 6.4 16.5 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RUS80400.1 - 5.8 4.9 35.9 7.2 4.6 35.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi IFT57 PF10498.9 RUS80400.1 - 6.3 5.7 7.6 8.5 5.2 7.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Somatomedin_B PF01033.17 RUS80401.1 - 2.7e-05 24.5 15.8 2.7e-05 24.5 15.8 2.4 2 0 0 2 2 2 1 Somatomedin B domain Usp PF00582.26 RUS80402.1 - 0.09 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein family Lectin_C PF00059.21 RUS80403.1 - 0.024 15.4 0.0 0.037 14.8 0.0 1.3 1 0 0 1 1 1 0 Lectin C-type domain EF-hand_13 PF17958.1 RUS80404.1 - 0.00073 19.3 5.8 29 4.5 0.0 5.6 2 2 3 6 6 6 0 EF-hand domain FANCI_S2 PF14676.6 RUS80404.1 - 0.0028 18.0 5.0 5.9 7.2 0.5 3.3 2 1 1 3 3 3 3 FANCI solenoid 2 Cytochrom_B_N_2 PF13631.6 RUS80404.1 - 0.0045 17.0 7.9 6.9 6.6 0.2 3.3 2 1 1 3 3 3 3 Cytochrome b(N-terminal)/b6/petB Transposase_20 PF02371.16 RUS80404.1 - 0.026 14.9 0.1 1 9.7 0.0 2.8 1 1 1 2 2 2 0 Transposase IS116/IS110/IS902 family RVT_2 PF07727.14 RUS80404.1 - 0.074 12.7 0.2 24 4.4 0.0 2.9 2 1 1 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_rich_CPCC PF14206.6 RUS80404.1 - 0.078 12.8 2.2 6.3 6.7 0.2 2.2 1 1 1 2 2 2 0 Cysteine-rich CPCC U71 PF17474.2 RUS80404.1 - 0.25 11.3 4.9 1.3e+02 2.6 0.1 4.1 4 0 0 4 4 4 0 Tegument protein UL11 homolog zf-CCCH_4 PF18044.1 RUS80404.1 - 7.2 6.5 11.3 93 3.0 0.1 4.2 4 0 0 4 4 4 0 CCCH-type zinc finger mRNA_triPase PF02940.15 RUS80405.1 - 0.0011 18.8 0.3 4.7 6.9 0.1 3.0 1 1 2 3 3 3 3 mRNA capping enzyme, beta chain CSTF_C PF14304.6 RUS80405.1 - 0.0039 16.7 34.0 14 5.4 0.3 9.0 1 1 10 11 11 11 11 Transcription termination and cleavage factor C-terminal OstA_2 PF13100.6 RUS80405.1 - 0.021 14.4 0.0 8 6.0 0.0 2.3 1 1 1 2 2 2 0 OstA-like protein RVT_1 PF00078.27 RUS80406.1 - 3.1e-05 23.6 0.0 6.1e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_9 PF14604.6 RUS80408.1 - 2.3e-37 126.6 0.5 1.2e-13 50.7 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 RUS80408.1 - 1.2e-35 120.8 0.0 1.9e-11 43.4 0.0 3.7 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 RUS80408.1 - 3.9e-29 100.1 0.2 1.2e-11 44.2 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.16 RUS80409.1 - 3.8e-14 52.3 0.0 9.5e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Sorbin homologous domain Arm PF00514.23 RUS80410.1 - 1.1e-12 47.5 17.0 0.00014 21.8 0.0 8.4 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 RUS80410.1 - 3.7e-06 26.5 1.0 3.7e-06 26.5 1.0 3.0 2 1 0 2 2 2 1 V-ATPase subunit H F-box-like PF12937.7 RUS80410.1 - 0.0092 15.9 0.5 2.8 7.9 0.1 3.1 3 0 0 3 3 3 1 F-box-like RTTN_N PF14726.6 RUS80410.1 - 0.049 14.4 4.2 22 5.9 0.0 5.0 5 2 1 6 6 6 0 Rotatin, an armadillo repeat protein, centriole functioning FR47 PF08445.10 RUS80410.1 - 0.05 13.6 0.2 0.32 11.0 0.2 2.4 3 0 0 3 3 3 0 FR47-like protein HEAT_EZ PF13513.6 RUS80410.1 - 0.092 13.3 3.6 2 9.0 0.1 4.6 4 0 0 4 4 4 0 HEAT-like repeat HSP20 PF00011.21 RUS80411.1 - 2.4e-20 72.6 1.4 2.9e-20 72.3 1.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS80411.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cadherin_pro PF08758.11 RUS80411.1 - 0.031 14.4 0.1 0.064 13.4 0.1 1.5 1 0 0 1 1 1 0 Cadherin prodomain like DUF4845 PF16137.5 RUS80411.1 - 0.076 13.9 0.2 0.18 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) HSP70 PF00012.20 RUS80412.1 - 1.4e-259 862.3 2.9 1.6e-259 862.1 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS80412.1 - 2.3e-16 59.6 0.0 5.7e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 RUS80412.1 - 0.00035 20.4 0.0 0.0013 18.5 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 RUS80412.1 - 0.0053 17.1 0.3 8.1 6.9 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 RUS80412.1 - 0.13 11.5 1.1 0.44 9.7 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase RRM_1 PF00076.22 RUS80413.1 - 4.1e-11 42.5 2.3 5.1e-11 42.2 0.4 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS80413.1 - 6.8e-05 22.8 0.1 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RUS80413.1 - 0.00027 21.0 0.1 0.00027 21.0 0.1 2.4 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 RUS80413.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif MULE PF10551.9 RUS80413.1 - 0.2 12.1 0.1 0.47 10.9 0.1 1.6 1 0 0 1 1 1 0 MULE transposase domain NINJA_B PF16136.5 RUS80413.1 - 5 7.5 11.0 7.5 7.0 5.6 2.3 2 0 0 2 2 2 0 Putative nuclear localisation signal TFIIA PF03153.13 RUS80414.1 - 0.31 11.0 15.6 0.47 10.4 15.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 RUS80414.1 - 1.2 9.0 8.3 1.7 8.5 8.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KASH_CCD PF14662.6 RUS80415.1 - 0.0013 18.6 0.8 0.0025 17.7 0.8 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 RUS80415.1 - 0.18 12.0 1.1 0.54 10.5 1.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper GIT_CC PF16559.5 RUS80415.1 - 0.29 11.0 1.7 0.72 9.8 1.7 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 RUS80415.1 - 1.2 9.8 4.2 0.55 10.9 0.3 2.4 2 1 0 2 2 2 0 Initiation control protein YabA RCDG1 PF15725.5 RUS80415.1 - 3 8.4 6.8 8 7.0 6.8 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein ZapB PF06005.12 RUS80415.1 - 5.3 7.6 8.2 0.14 12.6 1.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF1180 PF06679.12 RUS80415.1 - 6.5 7.1 8.8 2.7 8.4 3.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) IER PF05760.12 RUS80417.1 - 1e-28 101.7 18.9 1.4e-28 101.2 18.9 1.3 1 0 0 1 1 1 1 Immediate early response protein (IER) Nop14 PF04147.12 RUS80418.1 - 1 7.5 49.5 1.2 7.3 49.5 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 RUS80418.1 - 1.5 7.5 14.2 1.7 7.3 14.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Orthopox_C10L PF07020.11 RUS80418.1 - 4.8 8.0 17.2 4.7e+02 1.6 17.2 2.6 1 1 0 1 1 1 0 Orthopoxvirus C10L protein Shisa PF13908.6 RUS80419.1 - 5 7.3 6.5 8.9 6.5 6.5 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Kelch_1 PF01344.25 RUS80420.1 - 2.2e-30 104.0 16.9 1.4e-12 47.0 0.1 5.4 4 2 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 RUS80420.1 - 2e-20 72.3 2.4 1.7e-08 34.4 0.0 6.0 2 1 3 5 5 5 4 Kelch motif Kelch_3 PF13415.6 RUS80420.1 - 4.6e-14 52.3 2.2 3.4e-07 30.4 0.1 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS80420.1 - 6.5e-14 51.3 7.9 1.3e-05 24.9 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 RUS80420.1 - 1.2e-12 47.7 7.6 2.7e-07 30.5 0.0 5.0 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS80420.1 - 1.3e-11 44.2 4.2 0.0076 16.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif ParBc PF02195.18 RUS80420.1 - 0.2 12.0 0.3 0.46 10.8 0.3 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain Acyltransferase PF01553.21 RUS80421.1 - 1.3e-32 112.3 0.0 1.8e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DENN PF02141.21 RUS80422.1 - 3e-44 151.2 2.8 4.5e-44 150.6 2.8 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RUS80422.1 - 1.5e-09 38.4 1.1 3.2e-09 37.4 1.1 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 RUS80422.1 - 1.6e-09 37.6 0.7 4.2e-09 36.3 0.7 1.8 1 0 0 1 1 1 1 dDENN domain Imm42 PF15593.6 RUS80424.1 - 1.9e-05 25.2 2.7 1.6 9.2 0.2 4.3 1 1 2 3 3 3 3 Immunity protein 42 DUF5361 PF17318.2 RUS80424.1 - 0.00013 22.1 0.4 0.72 10.1 0.1 3.0 1 1 2 3 3 3 3 Family of unknown function (DUF5361) PH_15 PF17339.2 RUS80424.1 - 0.00029 20.7 11.8 1.8 8.5 0.2 4.2 1 1 4 5 5 5 5 PH domain DUF5599 PF18141.1 RUS80424.1 - 0.0015 18.7 2.2 2.6 8.4 0.1 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF5599) DIPSY PF11763.8 RUS80424.1 - 0.0082 16.3 2.9 0.66 10.2 2.9 2.2 1 1 0 1 1 1 1 Cell-wall adhesin ligand-binding C-terminal Inhibitor_I48 PF10467.9 RUS80424.1 - 0.01 15.7 5.9 3.9 7.3 0.8 3.2 1 1 2 3 3 3 0 Peptidase inhibitor clitocypin EMP24_GP25L PF01105.24 RUS80424.1 - 0.03 14.3 7.4 2.6 8.0 7.4 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YbjN PF10722.9 RUS80424.1 - 0.034 14.2 1.0 30 4.7 0.1 3.3 1 1 2 3 3 3 0 Putative bacterial sensory transduction regulator Arf PF00025.21 RUS80424.1 - 0.044 13.2 4.4 3.4 7.1 0.5 2.5 1 1 1 2 2 2 0 ADP-ribosylation factor family ParE_toxin PF05016.15 RUS80424.1 - 0.068 13.8 4.3 23 5.7 0.5 4.0 1 1 1 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE BNR_3 PF13859.6 RUS80424.1 - 0.085 12.1 0.7 0.25 10.6 0.7 1.7 1 1 0 1 1 1 0 BNR repeat-like domain PilI PF10623.9 RUS80424.1 - 0.28 11.3 13.8 9.4 6.5 1.7 3.6 1 1 5 6 6 6 0 Plasmid conjugative transfer protein PilI PGM1_C PF18105.1 RUS80424.1 - 2.5 7.7 18.0 51 3.5 0.1 5.6 1 1 2 3 3 3 0 PGM1 C-terminal domain DUF4487 PF14868.6 RUS80425.1 - 1.3e-06 27.5 0.3 1.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) DUF4487 PF14868.6 RUS80426.1 - 2.2e-15 56.5 0.0 2.2e-15 56.5 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4487) SesA PF17107.5 RUS80426.1 - 0.028 14.6 0.2 0.39 10.9 0.2 2.7 2 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TetR_C_32 PF09209.11 RUS80426.1 - 0.068 13.2 0.1 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain cNMP_binding PF00027.29 RUS80429.1 - 1.6e-10 40.9 0.0 1e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Mito_carr PF00153.27 RUS80430.1 - 1.6e-78 258.7 2.3 3.4e-27 94.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 RUS80430.1 - 4.4e-21 72.8 11.2 7.2e-08 31.5 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS80430.1 - 7.1e-21 74.4 5.2 1.4e-11 44.7 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS80430.1 - 7.9e-19 65.9 9.3 5e-05 22.9 0.5 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS80430.1 - 8.8e-16 56.6 9.3 0.00038 19.8 0.1 4.9 4 1 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 RUS80430.1 - 6e-08 33.0 2.7 0.00031 21.0 0.3 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RUS80430.1 - 8.1e-08 32.0 12.2 0.039 13.8 0.3 4.6 4 1 1 5 5 5 3 EF-hand domain pair Dockerin_1 PF00404.18 RUS80430.1 - 0.016 15.4 4.2 0.32 11.2 1.1 3.0 1 1 2 3 3 3 0 Dockerin type I domain EF-hand_10 PF14788.6 RUS80430.1 - 0.031 14.2 3.0 9.7 6.1 0.0 3.6 2 2 2 4 4 4 0 EF hand Caleosin PF05042.13 RUS80430.1 - 0.035 14.0 2.9 1.8 8.4 0.3 3.2 1 1 2 3 3 3 0 Caleosin related protein EF-hand_4 PF12763.7 RUS80430.1 - 0.37 10.8 2.9 1.1 9.2 0.9 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-C2H2 PF00096.26 RUS80431.1 - 1.5e-27 94.5 98.6 0.00098 19.5 0.4 12.7 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80431.1 - 3.9e-21 73.9 101.1 0.0025 18.5 0.5 13.2 13 0 0 13 13 13 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS80431.1 - 3.1e-18 65.3 94.0 1.3e-07 31.7 0.4 13.1 14 0 0 14 14 14 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS80431.1 - 2.1e-14 53.0 71.8 1.1e-05 25.1 2.3 11.5 11 0 0 11 11 11 6 C2H2-type zinc-finger domain zf-met PF12874.7 RUS80431.1 - 0.00056 20.2 55.2 0.072 13.5 4.7 9.0 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 RUS80431.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 11.3 5 3 8 13 13 13 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RUS80431.1 - 0.041 13.7 0.2 0.041 13.7 0.2 7.7 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS80431.1 - 0.097 13.0 0.0 0.097 13.0 0.0 10.4 11 0 0 11 11 11 0 Zinc-finger double-stranded RNA-binding Vps36-NZF-N PF16988.5 RUS80431.1 - 0.27 10.7 9.5 5.1 6.6 1.0 4.4 3 1 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.7 RUS80431.1 - 0.29 11.5 71.8 0.57 10.6 4.8 10.7 2 2 9 11 11 11 0 C2H2 type zinc-finger (2 copies) Tau95 PF09734.9 RUS80432.1 - 2.5e-33 115.8 0.3 6.1e-33 114.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 RUS80432.1 - 7.5e-29 100.5 0.0 1.5e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain TFIIF_beta PF02270.15 RUS80432.1 - 0.13 12.4 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain WBP-1 PF11669.8 RUS80434.1 - 0.011 16.3 0.2 0.023 15.3 0.2 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 PSI PF01437.25 RUS80435.1 - 0.0063 17.0 21.8 0.29 11.7 21.8 2.6 1 1 0 1 1 1 1 Plexin repeat Kelch_5 PF13854.6 RUS80436.1 - 1.6e-27 95.0 11.7 4.1e-06 26.7 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RUS80436.1 - 2.5e-23 81.8 9.1 2.2e-08 33.9 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS80436.1 - 6.9e-23 80.4 13.4 7.3e-05 22.9 0.1 7.6 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS80436.1 - 5.3e-20 71.0 12.3 0.00015 21.9 0.2 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.25 RUS80436.1 - 1e-13 50.6 5.4 0.00037 20.0 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Laminin_EGF PF00053.24 RUS80436.1 - 1.4e-08 34.8 45.1 5.1e-08 32.9 14.5 3.5 2 1 1 3 3 3 2 Laminin EGF domain Kelch_2 PF07646.15 RUS80436.1 - 2.3e-08 33.7 5.9 0.0013 18.7 0.0 6.0 6 0 0 6 6 6 1 Kelch motif EGF_2 PF07974.13 RUS80436.1 - 0.011 16.1 9.4 0.011 16.1 9.4 4.8 4 1 1 5 5 5 0 EGF-like domain EGF_Tenascin PF18720.1 RUS80436.1 - 5.5 7.1 34.1 0.21 11.6 6.1 3.7 3 0 0 3 3 3 0 Tenascin EGF domain PSI PF01437.25 RUS80437.1 - 2.7 8.6 14.8 2 9.0 6.1 2.2 2 0 0 2 2 2 0 Plexin repeat Kelch_4 PF13418.6 RUS80438.1 - 8.2e-33 112.2 19.8 6.8e-08 32.4 0.4 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS80438.1 - 4.6e-25 87.0 20.2 7e-07 29.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 RUS80438.1 - 5.6e-24 83.7 17.0 0.00035 20.5 0.4 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS80438.1 - 3.3e-21 75.1 27.4 9.1e-08 32.2 1.6 7.4 7 2 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS80438.1 - 1.3e-20 72.7 20.2 2.6e-06 26.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif CUB PF00431.20 RUS80438.1 - 8.2e-15 55.1 0.0 1.8e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 CUB domain Kelch_2 PF07646.15 RUS80438.1 - 5e-14 51.6 22.4 0.00096 19.0 0.2 6.5 6 0 0 6 6 6 5 Kelch motif EGF_2 PF07974.13 RUS80438.1 - 0.00016 21.9 34.2 0.00051 20.3 12.4 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS80438.1 - 0.079 13.6 19.2 0.056 14.1 5.8 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF DUF1668 PF07893.13 RUS80438.1 - 0.13 11.6 0.3 0.2 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) cEGF PF12662.7 RUS80438.1 - 0.18 11.8 9.2 1.7 8.6 1.6 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.27 RUS80438.1 - 0.31 11.4 24.9 0.056 13.8 9.1 2.6 2 0 0 2 2 2 0 EGF-like domain Rep_fac-A_C PF08646.10 RUS80439.1 - 5e-53 178.8 11.9 8.9e-52 174.7 7.8 2.7 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 RUS80439.1 - 1.6e-32 111.3 0.2 6.3e-32 109.4 0.1 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 RUS80439.1 - 1.5e-22 79.5 0.3 3.8e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 RUS80439.1 - 8.8e-10 38.4 0.0 3.7e-09 36.4 0.0 2.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 RUS80439.1 - 0.0048 17.2 0.5 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF223 Pox_vIL-18BP PF05566.12 RUS80439.1 - 0.039 14.2 0.5 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein CDC24_OB3 PF17244.2 RUS80439.1 - 0.11 12.2 3.6 0.62 9.7 1.3 2.4 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 Nuc_deoxyri_tr2 PF15891.5 RUS80440.1 - 8.4e-34 116.1 0.0 2e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 RUS80440.1 - 0.0058 16.7 0.0 0.96 9.5 0.0 2.4 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase EF-hand_7 PF13499.6 RUS80440.1 - 0.18 12.3 0.3 28 5.2 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain pair Methyltransf_25 PF13649.6 RUS80442.1 - 0.0061 17.2 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS80442.1 - 0.0094 16.7 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AceK PF06315.11 RUS80442.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Laminin_EGF PF00053.24 RUS80443.1 - 1.2e-18 67.0 50.5 4.5e-07 29.9 13.3 3.2 3 0 0 3 3 3 3 Laminin EGF domain Pox_I5 PF04713.12 RUS80443.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus protein I5 Mtc PF03820.17 RUS80444.1 - 6.6e-116 386.7 0.2 7.5e-116 386.5 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier zf-H2C2_2 PF13465.6 RUS80445.1 - 3.7e-38 128.3 115.8 4.5e-05 23.7 3.2 15.8 16 0 0 16 16 16 13 Zinc-finger double domain zf-C2H2 PF00096.26 RUS80445.1 - 8.9e-38 126.7 123.6 0.0016 18.8 0.5 15.3 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80445.1 - 2.8e-32 108.6 117.9 0.0056 17.4 0.8 15.3 15 0 0 15 15 15 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS80445.1 - 1.3e-18 66.8 67.3 0.0014 18.9 0.4 14.0 14 0 0 14 14 14 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS80445.1 - 2.7e-09 37.1 68.4 0.05 14.0 0.1 12.4 13 0 0 13 13 13 6 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RUS80445.1 - 3.4e-05 23.5 5.9 0.00086 19.0 1.6 14.8 16 1 0 16 16 16 8 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS80445.1 - 0.00082 19.3 4.3 0.006 16.6 0.4 14.0 14 1 0 14 14 14 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS80445.1 - 0.018 14.8 45.9 0.61 9.9 0.2 9.9 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 RUS80445.1 - 1.1 9.6 59.5 0.049 13.9 6.3 6.9 1 1 7 8 8 8 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 RUS80445.1 - 5.2 7.6 79.2 0.25 11.8 4.3 11.0 5 2 4 9 9 9 0 C2HE / C2H2 / C2HC zinc-binding finger UCH PF00443.29 RUS80446.1 - 1.5e-58 198.3 0.0 4.8e-58 196.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 RUS80446.1 - 2.2e-22 79.5 0.1 3.1e-13 50.2 0.0 3.1 3 1 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 RUS80446.1 - 9.6e-22 78.0 0.0 1.9e-18 67.1 0.0 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-CHY PF05495.12 RUS80446.1 - 0.015 15.8 0.4 0.015 15.8 0.4 3.9 4 1 0 4 4 4 0 CHY zinc finger Cu2_monooxygen PF01082.20 RUS80448.1 - 1.1e-40 138.9 0.0 7.5e-40 136.2 0.0 2.4 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 RUS80448.1 - 6.5e-30 103.7 1.6 1e-17 64.1 0.6 3.0 1 1 1 2 2 2 2 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 RUS80448.1 - 4e-14 52.9 0.1 1.3e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 DOMON domain TPR_1 PF00515.28 RUS80449.1 - 4.1e-08 32.7 0.1 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS80449.1 - 4.4e-08 32.6 0.0 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80449.1 - 0.00014 21.8 0.0 0.93 9.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS80449.1 - 0.00018 22.1 0.0 0.0038 17.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS80449.1 - 0.008 16.5 0.0 0.092 13.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80449.1 - 0.015 15.6 0.0 0.04 14.2 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 RUS80452.1 - 2.3e-38 131.7 0.7 3.9e-32 111.4 0.1 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Peptidase_C1 PF00112.23 RUS80452.1 - 2e-32 113.0 4.2 2e-32 113.0 4.2 3.0 2 1 0 2 2 1 1 Papain family cysteine protease Pkinase_Tyr PF07714.17 RUS80452.1 - 2.4e-32 112.2 0.0 5.6e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS80452.1 - 2.5e-30 105.7 0.0 2.5e-30 105.7 0.0 2.2 2 0 0 2 2 1 1 Protein kinase domain ANF_receptor PF01094.28 RUS80452.1 - 1.2e-11 44.4 0.3 9.1e-05 21.7 0.1 2.3 2 0 0 2 2 2 2 Receptor family ligand binding region Propeptide_C1 PF08127.13 RUS80452.1 - 9.5e-10 38.2 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide HNOBA PF07701.14 RUS80452.1 - 5.1e-06 26.1 1.2 5.1e-06 26.1 1.2 2.5 2 0 0 2 2 2 1 Heme NO binding associated DUF4228 PF14009.6 RUS80452.1 - 0.037 14.4 4.3 0.067 13.6 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DDHD PF02862.17 RUS80452.1 - 0.037 14.2 4.3 0.067 13.3 4.3 1.5 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 RUS80452.1 - 0.1 12.4 17.3 0.21 11.3 17.3 1.5 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RUS80452.1 - 0.22 9.8 45.4 0.42 8.8 18.6 2.1 2 0 0 2 2 2 0 CDC45-like protein CENP-N PF05238.13 RUS80452.1 - 0.41 9.9 11.8 0.83 8.9 11.8 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like XRN_N PF03159.18 RUS80452.1 - 0.6 9.5 12.7 1.1 8.6 12.7 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus CAF1 PF04857.20 RUS80452.1 - 1.2 8.3 10.7 6.6 5.8 11.3 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease SpoIIP PF07454.11 RUS80452.1 - 1.9 7.9 21.2 0.29 10.6 15.8 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Folliculin PF11704.8 RUS80452.1 - 2.6 7.9 13.1 5.2 6.9 13.1 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SOBP PF15279.6 RUS80452.1 - 3.3 8.2 11.1 7.2 7.1 11.1 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein SLC12 PF03522.15 RUS80452.1 - 3.4 6.6 18.3 5.9 5.8 18.3 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Eapp_C PF10238.9 RUS80452.1 - 4.7 7.3 16.5 21 5.2 16.5 2.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein SpoIIIAH PF12685.7 RUS80452.1 - 4.8 7.0 22.8 2.4 8.0 11.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein RPOL_N PF14700.6 RUS80452.1 - 4.9 6.5 22.7 8.2 5.7 22.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Hid1 PF12722.7 RUS80452.1 - 5.3 5.0 12.2 7.6 4.5 12.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 RUS80452.1 - 5.5 5.6 5.7 9.7 4.7 5.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 RUS80452.1 - 5.5 5.7 24.8 0.21 10.3 16.8 2.4 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 TraV PF09676.10 RUS80452.1 - 5.6 7.9 12.6 12 6.9 12.6 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) SAD_SRA PF02182.17 RUS80453.1 - 8.4e-55 184.8 0.4 1.4e-54 184.0 0.0 1.6 2 0 0 2 2 2 1 SAD/SRA domain DUF963 PF06131.11 RUS80453.1 - 4.2 6.9 35.3 1.3 8.5 3.5 6.3 3 2 2 5 5 5 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF5471 PF17565.2 RUS80453.1 - 9.2 6.6 24.0 29 5.0 2.0 6.4 2 1 5 7 7 7 0 Family of unknown function (DUF5471) Ribosomal_S26e PF01283.19 RUS80454.1 - 3e-53 178.8 9.3 3.4e-53 178.7 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PIP5K PF01504.18 RUS80455.1 - 2.1e-44 151.8 7.1 4.2e-35 121.3 1.3 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Spt20 PF12090.8 RUS80455.1 - 0.11 12.0 4.0 0.1 12.2 2.1 1.9 2 0 0 2 2 2 0 Spt20 family Cpn60_TCP1 PF00118.24 RUS80456.1 - 1.4e-15 56.9 0.0 2.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPF0172 PF03665.13 RUS80456.1 - 1 9.4 7.0 0.046 13.8 0.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) FYVE PF01363.21 RUS80457.1 - 1.5e-16 60.3 17.2 2.6e-16 59.5 17.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger DEP PF00610.21 RUS80457.1 - 7.1e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PKD_channel PF08016.12 RUS80458.1 - 3.3e-26 91.9 16.5 3.8e-26 91.7 16.5 1.0 1 0 0 1 1 1 1 Polycystin cation channel Nop14 PF04147.12 RUS80460.1 - 0.1 10.8 15.5 0.11 10.7 15.5 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RUS80460.1 - 2.2 6.6 12.9 2.7 6.3 12.9 1.1 1 0 0 1 1 1 0 Mpp10 protein eIF-3c_N PF05470.12 RUS80460.1 - 4.1 5.6 6.3 4.4 5.5 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 RUS80460.1 - 4.5 5.4 15.3 5.7 5.1 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS80460.1 - 6 6.2 18.9 7.5 5.9 18.9 1.1 1 0 0 1 1 1 0 SDA1 7tm_1 PF00001.21 RUS80461.1 - 4e-12 46.0 14.7 9.2e-12 44.8 14.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS80461.1 - 2e-10 40.4 1.5 2e-10 40.4 1.5 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS80461.1 - 1.1e-05 25.2 12.9 1.1e-05 25.2 12.9 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS80461.1 - 9.9e-05 21.8 13.0 0.00023 20.6 13.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DHHC PF01529.20 RUS80461.1 - 1.7 8.7 13.5 0.36 10.9 0.5 2.9 2 1 1 3 3 3 0 DHHC palmitoyltransferase Pkinase PF00069.25 RUS80463.1 - 1.5e-27 96.6 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80463.1 - 4.3e-15 55.7 0.0 6.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80463.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Myb_DNA-bind_7 PF15963.5 RUS80464.1 - 2.6e-24 84.9 1.3 5.6e-24 83.9 1.3 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 RUS80464.1 - 0.00045 20.4 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS80464.1 - 0.017 15.4 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Nse4-Nse3_bdg PF15412.6 RUS80465.1 - 3.3 7.9 0.0 3.3 7.9 0.0 4.1 4 1 1 5 5 5 0 Binding domain of Nse4/EID3 to Nse3-MAGE BUD22 PF09073.10 RUS80465.1 - 8.6 5.6 21.0 10 5.3 21.0 1.1 1 0 0 1 1 1 0 BUD22 Nucleo_P87 PF07267.11 RUS80465.1 - 9.6 4.9 14.8 12 4.6 14.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MFAP1 PF06991.11 RUS80466.1 - 2.4e-73 246.6 30.8 2.4e-73 246.6 30.8 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing RNA_pol_3_Rpc31 PF11705.8 RUS80466.1 - 0.00022 21.6 13.2 0.00022 21.6 13.2 3.5 2 1 1 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 GST_C_3 PF14497.6 RUS80467.1 - 3.5e-19 68.8 0.0 5.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS80467.1 - 2.3e-07 31.1 0.0 6.1e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS80467.1 - 8e-05 22.8 0.1 0.00014 22.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS80467.1 - 0.00023 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RUS80467.1 - 0.026 15.3 0.0 0.11 13.2 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Ald_Xan_dh_C2 PF02738.18 RUS80468.1 - 7.4e-143 476.9 0.3 1e-142 476.5 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 RUS80468.1 - 7.2e-26 90.0 0.1 1.9e-25 88.6 0.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 RUS80468.1 - 1.4e-21 77.0 0.0 4.5e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 RUS80468.1 - 2.7e-21 76.0 0.0 5.1e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 RUS80468.1 - 2.4e-19 69.4 0.0 5.2e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 RUS80468.1 - 6.6e-05 22.8 1.6 0.00024 21.0 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF2946 PF11162.8 RUS80468.1 - 0.8 10.4 3.2 17 6.1 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Toxin_3 PF00537.18 RUS80468.1 - 1.1 9.5 5.2 2.8 8.2 1.7 2.9 2 0 0 2 2 2 0 Scorpion toxin-like domain RVT_1 PF00078.27 RUS80469.1 - 1.1e-27 97.0 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_cyc PF00211.20 RUS80469.1 - 0.13 11.8 0.1 0.3 10.7 0.0 1.6 1 1 1 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Lectin_C PF00059.21 RUS80470.1 - 2.2e-45 153.8 15.6 3e-15 56.9 0.4 3.2 3 0 0 3 3 3 3 Lectin C-type domain UL45 PF05473.12 RUS80470.1 - 1e-08 35.1 9.1 0.015 14.9 0.1 4.7 2 1 2 4 4 4 3 UL45 protein, carbohydrate-binding C-type lectin-like Tme5_EGF_like PF09064.10 RUS80470.1 - 0.024 14.5 1.4 14 5.7 0.1 3.5 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like Integrase_H2C2 PF17921.1 RUS80471.1 - 3.3e-22 78.3 0.1 5.1e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS80471.1 - 1.2e-06 28.7 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS80471.1 - 4.4e-06 26.8 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCCH_4 PF18044.1 RUS80472.1 - 6.4e-07 29.0 16.8 7.5e-05 22.4 3.7 3.7 4 0 0 4 4 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RUS80472.1 - 1.8e-06 27.8 19.0 1.9e-05 24.5 5.7 4.2 5 0 0 5 5 5 2 Zinc finger domain zf-CCCH PF00642.24 RUS80472.1 - 1.5e-05 24.7 9.9 0.00038 20.3 1.4 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RUS80472.1 - 0.00016 22.3 12.4 0.011 16.4 0.3 3.2 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 RUS80472.1 - 0.00096 19.5 28.8 0.04 14.4 2.2 3.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger bZIP_1 PF00170.21 RUS80472.1 - 0.0099 16.0 0.5 0.023 14.8 0.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor zf-CCCH_3 PF15663.5 RUS80472.1 - 0.015 15.5 14.7 1.8 8.8 0.5 3.4 2 1 0 2 2 2 0 Zinc-finger containing family DivIC PF04977.15 RUS80472.1 - 0.028 14.2 0.4 0.028 14.2 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 RUS80472.1 - 0.12 12.5 4.0 0.12 12.4 0.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PBP1_TM PF14812.6 RUS80472.1 - 0.13 12.7 2.1 0.44 11.0 2.1 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HALZ PF02183.18 RUS80472.1 - 0.27 11.5 1.7 0.36 11.1 0.3 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-C3HC4_2 PF13923.6 RUS80473.1 - 7.2e-09 35.3 12.2 7.2e-09 35.3 12.2 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS80473.1 - 1.7e-08 34.2 11.3 1.7e-08 34.2 11.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS80473.1 - 4.4e-08 32.9 11.4 4.4e-08 32.9 11.4 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS80473.1 - 1.3e-07 31.9 13.9 1.3e-07 31.9 13.9 2.9 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS80473.1 - 7.7e-06 25.8 12.4 7.7e-06 25.8 12.4 2.8 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS80473.1 - 9.3e-06 25.4 9.5 9.3e-06 25.4 9.5 2.5 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS80473.1 - 0.00021 21.4 11.2 0.00021 21.4 11.2 3.0 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS80473.1 - 0.00028 20.8 12.8 0.00028 20.8 12.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS80473.1 - 0.0033 17.7 13.2 0.0033 17.7 13.2 2.7 2 1 0 2 2 1 1 RING-H2 zinc finger domain U-box PF04564.15 RUS80473.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 U-box domain DUF5429 PF17494.2 RUS80473.1 - 0.086 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5429) Ski_Sno PF02437.17 RUS80474.1 - 0.0056 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family YL1_C PF08265.11 RUS80474.1 - 0.038 13.8 0.0 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain RVT_1 PF00078.27 RUS80476.1 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 RUS80476.1 - 2.2e-05 23.9 3.8 2.2e-05 23.9 3.8 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RUS80476.1 - 5.1e-05 23.1 10.6 9.3e-05 22.2 10.6 1.4 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 RUS80476.1 - 0.4 10.3 7.2 0.91 9.2 7.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pox_vIL-18BP PF05566.12 RUS80476.1 - 0.86 9.8 3.0 9.6 6.4 0.8 2.5 1 1 1 2 2 2 0 Orthopoxvirus interleukin 18 binding protein FYVE_2 PF02318.16 RUS80476.1 - 1.1 9.5 7.0 2.7 8.2 7.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 RUS80476.1 - 1.2 9.6 7.7 5.3 7.4 4.4 2.3 2 0 0 2 2 2 0 C1 domain CTNNB1_binding PF08347.11 RUS80477.1 - 0.055 13.7 1.7 0.062 13.5 1.7 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Transformer PF06495.11 RUS80477.1 - 0.18 11.9 9.7 0.23 11.6 9.7 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein zf-C2H2_4 PF13894.6 RUS80478.1 - 9.3e-19 66.5 61.8 0.0016 19.1 1.0 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS80478.1 - 3.4e-17 61.8 69.1 0.0033 17.8 1.4 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS80478.1 - 1.4e-11 44.2 58.3 5.7e-05 23.4 1.6 9.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS80478.1 - 0.0056 16.9 1.5 0.0056 16.9 1.5 8.9 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS80478.1 - 0.0068 16.8 49.3 0.35 11.3 0.3 9.1 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS80478.1 - 0.0096 15.9 49.7 0.0099 15.9 0.6 8.0 8 0 0 8 8 7 3 C2H2-type zinc finger Med12 PF09497.10 RUS80478.1 - 0.049 13.9 0.6 0.13 12.6 0.1 2.0 2 0 0 2 2 1 0 Transcription mediator complex subunit Med12 SET PF00856.28 RUS80478.1 - 0.095 13.1 0.0 0.095 13.1 0.0 3.6 3 2 0 3 3 3 0 SET domain zf-C2H2_8 PF15909.5 RUS80478.1 - 6.9 7.0 25.3 6.4 7.2 4.7 4.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon AT_hook PF02178.19 RUS80478.1 - 7.5 6.8 33.7 0.35 10.9 3.1 3.7 3 0 0 3 3 3 0 AT hook motif Otopetrin PF03189.13 RUS80478.1 - 7.9 5.2 10.9 21 3.8 10.9 1.7 1 0 0 1 1 1 0 Otopetrin CHCH PF06747.13 RUS80479.1 - 0.0053 16.8 6.9 0.011 15.8 6.9 1.6 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 RUS80479.1 - 0.014 15.6 1.7 0.026 14.8 1.7 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 RUS80479.1 - 0.25 11.7 7.6 0.28 11.5 6.8 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Rft-1 PF04506.13 RUS80480.1 - 1e-130 436.9 22.5 1.1e-130 436.8 22.5 1.0 1 0 0 1 1 1 1 Rft protein Nckap1 PF09735.9 RUS80480.1 - 0.023 12.7 0.1 0.03 12.3 0.1 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein MFS_1 PF07690.16 RUS80481.1 - 1.5e-13 50.5 42.0 1.4e-10 40.7 13.1 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily DAGK_cat PF00781.24 RUS80482.1 - 2.3e-25 88.6 0.0 3.5e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-H2C2_5 PF13909.6 RUS80483.1 - 5.3 6.9 5.7 12 5.7 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PT PF04886.12 RUS80484.1 - 5.1e-08 32.3 57.7 3e-06 26.7 18.8 3.4 3 0 0 3 3 3 3 PT repeat U-box PF04564.15 RUS80484.1 - 0.00013 22.1 2.5 0.46 10.7 0.4 2.8 1 1 0 2 2 2 2 U-box domain Sigma70_r4 PF04545.16 RUS80485.1 - 2.6e-06 26.9 5.5 5.5 6.6 0.0 7.6 2 2 8 10 10 10 2 Sigma-70, region 4 HTH_28 PF13518.6 RUS80485.1 - 1.2e-05 25.4 5.2 9.1 6.5 0.1 6.4 1 1 5 6 6 6 2 Helix-turn-helix domain RNase_T PF00929.24 RUS80485.1 - 0.00043 20.9 0.9 17 5.9 0.1 4.1 1 1 3 4 4 4 2 Exonuclease Sigma70_r4_2 PF08281.12 RUS80485.1 - 0.0009 18.9 10.0 35 4.2 0.0 7.4 3 1 5 8 8 8 0 Sigma-70, region 4 HTH_24 PF13412.6 RUS80485.1 - 0.004 16.7 1.6 1.6e+02 2.0 0.0 6.7 8 0 0 8 8 8 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 RUS80485.1 - 0.0077 16.1 33.6 0.9 9.5 0.1 8.3 7 3 1 8 8 8 2 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 RUS80485.1 - 0.12 12.2 8.5 62 3.6 0.2 6.2 2 2 5 7 7 7 0 Homeodomain-like domain GerE PF00196.19 RUS80485.1 - 1 8.9 14.6 44 3.7 0.0 7.0 2 1 6 8 8 8 0 Bacterial regulatory proteins, luxR family Gly_transf_sug PF04488.15 RUS80487.1 - 3.9e-08 33.8 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS80487.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein SF3A3 PF16837.5 RUS80487.1 - 0.11 13.1 2.0 1.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DEAD PF00270.29 RUS80488.1 - 1.8e-46 158.1 0.0 4.8e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.29 RUS80488.1 - 3.6e-25 87.6 17.7 9.4e-15 54.2 2.5 3.4 4 0 0 4 4 4 2 KH domain Helicase_C PF00271.31 RUS80488.1 - 1.4e-16 60.8 0.1 2.2e-14 53.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_2 PF07650.17 RUS80488.1 - 1.1e-08 34.7 4.2 0.0011 18.8 0.1 2.8 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 RUS80488.1 - 5.2e-05 23.2 0.1 0.27 11.3 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 RUS80488.1 - 0.00022 21.2 4.4 0.012 15.6 1.1 2.6 2 0 0 2 2 2 2 NusA-like KH domain ResIII PF04851.15 RUS80488.1 - 0.00024 21.1 0.0 0.00062 19.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KH_4 PF13083.6 RUS80488.1 - 0.021 14.7 8.4 0.66 9.9 0.3 3.4 2 2 1 3 3 3 0 KH domain ERCC3_RAD25_C PF16203.5 RUS80488.1 - 0.029 13.6 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 RUS80488.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PDZ PF00595.24 RUS80489.1 - 2e-15 56.9 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS80489.1 - 1.5e-14 53.6 0.7 2.9e-14 52.7 0.7 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS80489.1 - 6.6e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain EBP50_C PF09007.11 RUS80489.1 - 0.3 12.1 11.1 2.2 9.3 11.1 2.4 1 1 0 1 1 1 0 EBP50, C-terminal Mito_fiss_reg PF05308.11 RUS80489.1 - 3 7.9 13.0 9.4 6.2 12.9 2.0 1 1 0 1 1 1 0 Mitochondrial fission regulator Frag1 PF10277.9 RUS80490.1 - 2e-23 83.1 15.8 7.4e-19 68.2 4.2 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family Frag1 PF10277.9 RUS80491.1 - 1.3e-31 109.8 11.5 1.5e-31 109.7 11.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ion_trans PF00520.31 RUS80492.1 - 9.6e-43 146.2 8.2 1.3e-42 145.8 8.2 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS80492.1 - 7.2e-28 96.8 0.1 2e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF3399 PF11879.8 RUS80492.1 - 6.2e-16 58.6 0.1 1.5e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) Shal-type PF11601.8 RUS80492.1 - 1e-14 53.7 8.0 1.7e-14 53.0 8.0 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans_2 PF07885.16 RUS80492.1 - 5.8e-12 45.4 6.1 5.8e-12 45.4 6.1 2.3 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 RUS80492.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 RUS80492.1 - 0.061 12.0 3.2 0.099 11.3 3.2 1.3 1 0 0 1 1 1 0 Polycystin cation channel EMC3_TMCO1 PF01956.16 RUS80492.1 - 1.8 8.3 3.4 30 4.3 0.5 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Urocanase_C PF17392.2 RUS80493.1 - 6.6e-89 296.5 2.0 1.1e-88 295.8 2.0 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 RUS80493.1 - 1.1e-85 286.6 0.0 1.6e-85 286.0 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 RUS80493.1 - 4.3e-58 194.5 0.1 9.2e-58 193.5 0.1 1.6 1 0 0 1 1 1 1 Urocanase N-terminal domain Med20 PF08612.11 RUS80494.1 - 6.1e-40 137.0 0.0 7e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex p450 PF00067.22 RUS80495.1 - 4.7e-26 91.6 2.2 6.9e-25 87.7 2.2 2.0 1 1 0 1 1 1 1 Cytochrome P450 THAP PF05485.12 RUS80499.1 - 1.9e-15 57.5 0.6 2.3e-15 57.3 0.6 1.1 1 0 0 1 1 1 1 THAP domain zf-C2H2_4 PF13894.6 RUS80500.1 - 0.087 13.7 54.9 0.028 15.2 2.2 7.7 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.12 RUS80500.1 - 0.13 12.6 31.0 0.1 12.9 2.7 4.9 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding FpoO PF10621.9 RUS80500.1 - 2.5 8.4 9.2 0.37 11.1 4.5 2.1 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-C2H2_jaz PF12171.8 RUS80500.1 - 9.4 6.7 33.5 0.39 11.1 0.6 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding fn3 PF00041.21 RUS80501.1 - 6.3e-63 209.1 14.4 7.3e-16 58.3 0.9 6.0 5 1 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS80501.1 - 1.3e-15 57.7 10.2 0.0062 17.1 0.2 5.4 5 0 0 5 5 5 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS80501.1 - 7.4e-14 51.9 2.4 0.0033 17.7 0.0 5.5 5 0 0 5 5 5 3 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.16 RUS80501.1 - 7.6e-10 38.7 0.0 8.1e-09 35.4 0.0 2.8 4 0 0 4 4 4 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS80501.1 - 2.6e-08 34.3 0.1 6.7e-07 29.8 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 RUS80501.1 - 0.0001 22.6 0.0 0.0004 20.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS80501.1 - 0.00011 22.3 0.0 0.0044 17.2 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain DUF2369 PF10179.9 RUS80501.1 - 0.0056 17.0 0.3 45 4.5 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 RUS80502.1 - 1.6e-10 41.2 0.5 2.3e-10 40.7 0.2 1.5 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.10 RUS80502.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 RUS80503.1 - 1.1e-33 115.4 7.5 1.7e-10 41.1 0.1 3.9 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS80503.1 - 7.6e-07 29.6 2.4 0.0089 16.6 0.1 4.4 3 2 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS80503.1 - 0.0053 17.1 0.0 2.7 8.3 0.0 2.8 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III Myosin_N PF02736.19 RUS80504.1 - 0.044 13.6 0.1 0.044 13.6 0.1 2.0 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain VirE2 PF07229.12 RUS80504.1 - 0.28 9.8 4.9 0.44 9.1 4.9 1.2 1 0 0 1 1 1 0 VirE2 Chromadorea_ALT PF05535.12 RUS80505.1 - 0.0072 16.5 0.2 12 6.1 0.0 4.1 1 1 5 6 6 6 1 Chromadorea ALT protein DUF3135 PF11333.8 RUS80505.1 - 0.14 12.4 2.1 1.6e+02 2.7 0.0 4.1 2 1 4 6 6 6 0 Protein of unknown function (DUF3135) DUF2626 PF11117.8 RUS80505.1 - 0.21 12.3 2.1 25 5.7 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2626) DUF3254 PF11630.8 RUS80505.1 - 0.22 11.7 0.1 78 3.5 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3254) EF-hand_7 PF13499.6 RUS80506.1 - 2.1e-10 40.9 0.2 3.5e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS80506.1 - 2.2e-07 29.9 0.6 0.011 15.2 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS80506.1 - 8.9e-07 28.4 0.9 0.0042 16.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS80506.1 - 6.6e-06 25.4 0.2 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS80506.1 - 1.8e-05 24.5 0.4 0.0059 16.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS80506.1 - 0.031 14.6 0.0 0.26 11.6 0.0 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 RUS80507.1 - 9.8e-11 42.0 2.1 2.2e-10 40.8 2.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS80507.1 - 1.3e-10 40.1 3.1 0.00022 20.6 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS80507.1 - 5.3e-09 35.3 0.7 0.0015 18.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS80507.1 - 2.4e-06 26.7 0.3 0.0087 15.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS80507.1 - 2.5e-05 24.1 2.9 0.05 13.4 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS80507.1 - 0.026 14.9 0.2 0.29 11.4 0.2 2.2 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RUS80507.1 - 0.064 13.6 0.4 0.54 10.6 0.4 2.5 2 1 0 2 2 2 0 EF-hand domain PHB_acc_N PF07879.11 RUS80507.1 - 0.12 12.5 2.2 0.56 10.3 0.8 2.7 2 1 1 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain LMSTEN PF07988.12 RUS80507.1 - 0.76 9.3 2.6 13 5.3 0.1 2.6 3 0 0 3 3 3 0 LMSTEN motif Phage_int_SAM_5 PF13102.6 RUS80508.1 - 0.014 15.7 0.3 6.3 7.2 0.0 2.8 3 1 1 4 4 4 0 Phage integrase SAM-like domain Atg14 PF10186.9 RUS80508.1 - 0.37 9.8 7.9 0.51 9.4 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 RUS80508.1 - 6.9 6.1 8.7 9 5.8 8.7 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4523 PF15023.6 RUS80510.1 - 2.7e-07 30.6 0.0 4.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RR_TM4-6 PF06459.12 RUS80510.1 - 2.4 7.9 12.6 3.9 7.2 12.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tubulin PF00091.25 RUS80511.1 - 8.8e-68 228.4 0.0 1.2e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS80511.1 - 3.3e-49 166.2 0.0 5.1e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS80511.1 - 0.0077 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 RUS80512.1 - 2.7e-63 213.8 1.3 7.4e-63 212.3 0.0 2.1 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS80512.1 - 1e-47 161.4 0.0 1.8e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Atg14 PF10186.9 RUS80512.1 - 0.04 13.0 16.7 0.062 12.4 16.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 eIF-3_zeta PF05091.12 RUS80512.1 - 1.3 7.9 16.6 1.9 7.4 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 RUS80512.1 - 1.8 7.8 15.1 2.8 7.2 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 RUS80512.1 - 3.3 6.4 18.4 4.6 5.9 18.4 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RUS80512.1 - 3.8 5.7 21.6 5.4 5.2 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 RUS80512.1 - 4.6 7.3 10.4 8.3 6.5 10.4 1.5 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 RUS80512.1 - 6.1 6.8 8.0 9.4 6.2 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 RUS80513.1 - 0.00023 21.2 0.1 0.033 14.3 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS80513.1 - 0.00059 20.4 5.0 0.19 12.4 0.1 4.8 4 2 0 4 4 4 1 Immunoglobulin domain V-set PF07686.17 RUS80513.1 - 0.0011 19.1 3.0 0.024 14.8 0.2 3.5 3 2 0 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS80513.1 - 0.011 15.3 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Pox_A21 PF05323.12 RUS80513.1 - 0.068 13.7 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Poxvirus A21 Protein PROCT PF08084.11 RUS80513.1 - 0.15 12.0 1.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 PROCT (NUC072) domain Fez1 PF06818.15 RUS80514.1 - 0.0041 17.6 13.2 0.0041 17.6 13.2 2.4 1 1 1 2 2 2 2 Fez1 Spc7 PF08317.11 RUS80514.1 - 0.0058 15.6 11.8 0.0058 15.6 11.8 2.9 1 1 2 3 3 3 3 Spc7 kinetochore protein PKcGMP_CC PF16808.5 RUS80514.1 - 0.0073 16.1 4.5 1.3 8.9 0.2 3.5 2 1 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Val_tRNA-synt_C PF10458.9 RUS80514.1 - 0.011 16.0 0.9 0.011 16.0 0.9 4.0 5 0 0 5 5 5 0 Valyl tRNA synthetase tRNA binding arm Macoilin PF09726.9 RUS80514.1 - 0.018 13.7 17.7 0.025 13.2 17.7 1.2 1 0 0 1 1 1 0 Macoilin family TMF_DNA_bd PF12329.8 RUS80514.1 - 0.032 14.2 24.1 0.059 13.4 6.9 4.0 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 RUS80514.1 - 0.04 14.0 33.7 0.69 10.0 2.0 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 RUS80514.1 - 0.054 13.6 27.6 1.9 8.6 16.8 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Hsk3 PF08227.11 RUS80514.1 - 0.076 13.4 1.3 0.076 13.4 1.3 2.6 3 0 0 3 3 1 0 DASH complex subunit Hsk3 like bZIP_1 PF00170.21 RUS80514.1 - 0.079 13.1 16.3 3.1 7.9 4.1 4.2 4 0 0 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 RUS80514.1 - 0.15 12.6 28.4 0.82 10.2 6.1 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 RUS80514.1 - 0.22 11.6 25.1 2.1 8.4 0.5 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) OmpH PF03938.14 RUS80514.1 - 0.35 11.2 25.6 0.58 10.5 10.0 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ATG16 PF08614.11 RUS80514.1 - 0.42 10.8 30.0 0.14 12.4 18.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 RUS80514.1 - 0.5 9.2 19.4 1.7 7.5 19.4 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1993 PF09351.10 RUS80514.1 - 0.57 10.3 7.8 0.67 10.1 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) SlyX PF04102.12 RUS80514.1 - 0.61 10.7 27.5 0.068 13.8 3.5 4.5 1 1 2 4 4 4 0 SlyX DUF724 PF05266.14 RUS80514.1 - 1 9.2 22.5 0.34 10.7 12.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1192 PF06698.11 RUS80514.1 - 1.1 9.4 5.2 2.6 8.2 1.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) DUF745 PF05335.13 RUS80514.1 - 1.2 8.8 20.8 2.3 7.9 13.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 RUS80514.1 - 1.3 9.4 22.6 3.4 8.0 10.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) PIN_12 PF16289.5 RUS80514.1 - 1.4 9.4 7.0 1.8 9.1 6.2 1.7 1 1 0 1 1 1 0 PIN domain Tropomyosin_1 PF12718.7 RUS80514.1 - 1.5 8.9 25.4 0.88 9.7 13.9 3.1 1 1 1 2 2 2 0 Tropomyosin like DUF812 PF05667.11 RUS80514.1 - 1.6 7.5 28.1 8.5 5.1 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GAS PF13851.6 RUS80514.1 - 1.8 7.9 27.5 1.1 8.6 10.3 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Rx_N PF18052.1 RUS80514.1 - 2.5 8.4 16.2 7.2 7.0 2.4 3.7 2 1 2 4 4 4 0 Rx N-terminal domain DUF4407 PF14362.6 RUS80514.1 - 2.6 7.3 24.0 2 7.7 12.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 RUS80514.1 - 3 7.8 14.5 2.9 7.8 0.9 3.8 3 2 0 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 RUS80514.1 - 3.2 7.2 25.2 0.36 10.4 14.3 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 RUS80514.1 - 3.3 7.9 24.8 0.71 10.1 11.4 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.6 RUS80514.1 - 3.4 7.0 26.2 1.9e+03 -2.0 26.2 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) YabA PF06156.13 RUS80514.1 - 4 8.1 23.4 1.3 9.7 2.2 4.1 1 1 3 4 4 4 0 Initiation control protein YabA YlqD PF11068.8 RUS80514.1 - 4 7.8 28.3 0.29 11.5 12.8 3.4 1 1 1 2 2 2 0 YlqD protein BLOC1_2 PF10046.9 RUS80514.1 - 5.2 7.4 16.1 8.2 6.8 5.3 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM76 PF16046.5 RUS80514.1 - 6.6 6.0 19.6 12 5.2 19.5 1.5 1 1 0 1 1 1 0 FAM76 protein Occludin_ELL PF07303.13 RUS80514.1 - 6.6 7.5 14.2 18 6.1 1.8 3.6 1 1 2 3 3 3 0 Occludin homology domain Atg14 PF10186.9 RUS80514.1 - 6.9 5.7 27.7 1.5 7.8 4.1 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4446 PF14584.6 RUS80514.1 - 7.6 6.5 18.4 2.2 8.3 1.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF4446) SseC PF04888.12 RUS80515.1 - 0.0038 16.9 1.3 0.0038 16.9 1.3 2.0 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family DUF3584 PF12128.8 RUS80515.1 - 0.044 11.3 30.6 0.059 10.9 30.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 RUS80515.1 - 0.061 13.8 27.2 1.1 9.7 9.4 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4709 PF15821.5 RUS80515.1 - 0.09 13.1 23.9 0.26 11.6 0.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) AAA_13 PF13166.6 RUS80515.1 - 0.21 10.2 26.6 2.2 6.8 26.9 2.3 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 RUS80515.1 - 0.23 11.9 38.2 1.1 9.7 23.7 2.5 1 1 1 2 2 2 0 Fez1 DUF812 PF05667.11 RUS80515.1 - 0.34 9.7 36.7 0.061 12.2 7.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 RUS80515.1 - 0.43 10.6 12.7 0.041 13.9 2.9 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 RUS80515.1 - 0.47 10.5 23.0 1.7 8.7 2.0 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 RUS80515.1 - 0.57 10.8 34.9 2 9.1 5.4 5.3 2 1 3 5 5 5 0 SlyX Thiamine_BP PF01910.17 RUS80515.1 - 0.58 10.1 5.8 2.2 8.3 0.5 3.1 3 0 0 3 3 3 0 Thiamine-binding protein Laminin_II PF06009.12 RUS80515.1 - 1.1 9.3 17.4 2.2 8.3 5.3 2.9 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 RUS80515.1 - 1.9 7.3 40.0 3.6 6.4 14.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 RUS80515.1 - 2.1 9.0 38.6 0.86 10.2 14.7 4.0 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 RUS80515.1 - 2.2 8.5 43.0 3.8 7.7 24.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2937 PF11157.8 RUS80515.1 - 2.2 8.0 11.8 0.29 10.8 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF4200 PF13863.6 RUS80515.1 - 3 8.3 44.7 0.66 10.4 1.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) YojJ PF10372.9 RUS80515.1 - 9.6 6.4 7.6 29 4.8 1.7 3.1 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus MARVEL PF01284.23 RUS80516.1 - 1.3e-06 28.5 9.5 2.8e-06 27.4 9.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Cyd_oper_YbgE PF09600.10 RUS80516.1 - 0.0011 19.3 11.0 0.0063 16.9 3.1 3.0 3 0 0 3 3 3 2 Cyd operon protein YbgE (Cyd_oper_YbgE) SIT PF15330.6 RUS80516.1 - 0.057 13.9 0.0 0.057 13.9 0.0 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF373 PF04123.13 RUS80516.1 - 0.079 12.4 2.6 0.097 12.1 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Keratin_assoc PF09775.9 RUS80516.1 - 0.17 11.6 8.1 0.32 10.7 8.1 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Clathrin PF00637.20 RUS80517.1 - 4.6e-17 62.2 31.7 0.00011 22.1 0.0 10.1 6 2 2 10 10 10 5 Region in Clathrin and VPS WD40 PF00400.32 RUS80517.1 - 7.8e-11 42.4 0.9 3 8.9 0.0 7.2 7 0 0 7 7 6 2 WD domain, G-beta repeat TPR_7 PF13176.6 RUS80517.1 - 6.4e-07 29.0 24.0 0.27 11.3 0.1 11.1 10 2 1 11 11 11 3 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 RUS80517.1 - 1.2e-06 28.8 0.5 2 8.7 0.0 5.9 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 RUS80517.1 - 0.0014 18.6 37.4 0.053 13.8 0.2 12.3 13 0 0 13 13 13 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RUS80517.1 - 0.0041 16.2 15.1 0.019 14.0 0.2 5.9 4 2 1 6 6 6 1 Coatomer WD associated region TPR_2 PF07719.17 RUS80517.1 - 0.022 14.8 46.6 0.21 11.8 0.3 12.3 13 1 0 13 13 13 0 Tetratricopeptide repeat RICTOR_V PF14668.6 RUS80517.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 TPR_1 PF00515.28 RUS80517.1 - 1.5 8.8 38.9 1.3 9.0 0.1 10.5 12 1 1 13 13 13 0 Tetratricopeptide repeat YpsA PF06908.11 RUS80517.1 - 2 8.4 7.0 18 5.3 0.0 4.3 4 0 0 4 4 4 0 YspA SLOG family TPR_14 PF13428.6 RUS80517.1 - 3 8.9 33.4 1e+02 4.1 0.1 12.4 10 3 3 13 13 13 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 RUS80517.1 - 3.5 8.4 6.9 51 4.6 0.1 4.3 3 0 0 3 3 3 0 Cytochrome b562 Mad3_BUB1_I PF08311.12 RUS80517.1 - 3.5 7.6 18.4 3.9 7.5 0.2 6.4 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 Sec16_C PF12931.7 RUS80517.1 - 3.6 7.2 7.3 4.1 7.0 0.2 3.8 3 1 1 4 4 4 0 Sec23-binding domain of Sec16 TPR_19 PF14559.6 RUS80517.1 - 5.7 7.5 27.1 0.39 11.3 0.1 8.7 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80519.1 - 3.3e-29 101.0 10.6 0.00015 22.0 0.0 6.4 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 RUS80519.1 - 3.9e-11 42.4 1.0 2.1 8.3 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS80519.1 - 3.6e-07 29.7 15.4 0.029 14.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS80519.1 - 1.3e-06 28.1 19.1 0.82 9.9 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80519.1 - 0.003 17.6 29.1 0.61 10.4 0.1 8.1 8 2 0 8 8 8 2 Tetratricopeptide repeat MIT PF04212.18 RUS80519.1 - 0.032 14.3 2.6 5.1 7.2 0.0 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CM1 PF03026.15 RUS80519.1 - 0.032 13.6 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Influenza C virus M1 protein TPR_7 PF13176.6 RUS80519.1 - 0.045 13.8 4.2 18 5.6 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PBP1_TM PF14812.6 RUS80519.1 - 0.098 13.0 1.9 0.32 11.4 1.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CheC PF04509.12 RUS80519.1 - 0.2 11.6 0.1 0.65 10.0 0.1 1.9 1 0 0 1 1 1 0 CheC-like family Clathrin PF00637.20 RUS80519.1 - 2 8.3 5.2 2.7 7.9 0.0 3.4 3 1 0 4 4 4 0 Region in Clathrin and VPS Ank_4 PF13637.6 RUS80520.1 - 7.5e-15 55.1 0.4 1.9e-07 31.5 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS80520.1 - 1.4e-11 44.8 0.1 2.9e-10 40.6 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS80520.1 - 1.7e-11 44.0 0.1 4e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS80520.1 - 2.3e-11 43.7 0.1 1.2e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS80520.1 - 1.1e-10 40.8 0.1 3.9e-06 26.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Osmo_CC PF08946.10 RUS80520.1 - 0.082 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil PhyH PF05721.13 RUS80521.1 - 1.2e-32 113.9 0.0 1.6e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 RUS80521.1 - 0.012 14.5 0.1 0.56 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 RUS80521.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.8 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DBR1 PF05011.13 RUS80521.1 - 0.082 13.3 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Sad1_UNC PF07738.13 RUS80522.1 - 8.3e-25 87.3 0.0 1.4e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SlyX PF04102.12 RUS80522.1 - 0.062 13.9 9.6 0.39 11.4 0.9 3.3 1 1 1 2 2 2 0 SlyX Ank_2 PF12796.7 RUS80523.1 - 1.5e-67 224.1 14.1 1.3e-11 44.9 0.1 10.0 2 1 9 12 12 12 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS80523.1 - 4e-57 189.9 5.1 1.1e-09 38.7 0.0 12.7 6 2 5 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS80523.1 - 2.9e-46 150.1 7.3 0.00024 21.3 0.0 15.3 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 RUS80523.1 - 1.1e-43 145.8 18.6 5.3e-05 23.5 0.0 14.2 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 RUS80523.1 - 2.1e-41 139.4 8.9 5.1e-05 23.5 0.0 9.6 8 2 3 11 11 11 9 Ankyrin repeats (many copies) DUF4573 PF15140.6 RUS80524.1 - 0.0046 16.8 0.0 2.1 8.1 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4573) LIM PF00412.22 RUS80525.1 - 1.5e-31 108.4 10.7 1e-15 57.7 4.2 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS80525.1 - 5.4e-18 64.6 2.0 9e-18 63.9 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS80525.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Menin PF05053.13 RUS80525.1 - 0.034 12.5 8.5 0.04 12.3 8.5 1.1 1 0 0 1 1 1 0 Menin RP-C_C PF11800.8 RUS80525.1 - 0.059 13.5 5.3 0.083 13.0 5.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Striatin PF08232.12 RUS80525.1 - 0.092 13.3 7.6 0.14 12.8 7.6 1.2 1 0 0 1 1 1 0 Striatin family PNISR PF15996.5 RUS80525.1 - 0.79 10.0 10.2 2 8.7 10.2 1.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR TNFR_c6 PF00020.18 RUS80525.1 - 0.91 10.0 7.5 1.9 8.9 0.2 3.2 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region zf-dskA_traR PF01258.17 RUS80525.1 - 1.4 9.0 6.3 1 9.4 0.4 2.8 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Presenilin PF01080.17 RUS80525.1 - 1.7 7.3 9.5 2.2 7.0 9.5 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 RUS80525.1 - 2.2 8.3 4.5 2.8 7.9 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GCD14 PF08704.10 RUS80525.1 - 2.2 7.9 4.5 3.3 7.3 4.5 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MAP17 PF15807.5 RUS80525.1 - 2.8 8.2 9.1 4.4 7.5 9.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Macoilin PF09726.9 RUS80525.1 - 3.4 6.1 11.9 4.1 5.8 11.9 1.1 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 RUS80525.1 - 3.9 6.2 12.7 5.3 5.7 12.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CSG2 PF16965.5 RUS80525.1 - 4.8 6.0 4.2 6.1 5.7 4.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 RUS80525.1 - 5.2 6.2 7.2 7.7 5.6 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 RUS80526.1 - 0.007 14.9 10.8 0.0092 14.5 10.8 1.1 1 0 0 1 1 1 1 Mpp10 protein eIF-3c_N PF05470.12 RUS80526.1 - 0.11 10.8 2.2 0.11 10.8 2.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RUS80526.1 - 0.27 9.4 23.2 0.35 9.0 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS80526.1 - 0.55 8.3 39.1 0.78 7.8 39.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 RUS80526.1 - 1.4 8.0 43.5 2 7.5 43.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RUS80526.1 - 3.2 6.0 22.0 4.5 5.5 22.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 RUS80526.1 - 8.6 5.7 20.5 14 5.0 20.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 RUS80526.1 - 9 4.7 25.3 12 4.3 25.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 RUS80529.1 - 5.2 5.7 8.2 8.3 5.1 8.2 1.2 1 0 0 1 1 1 0 Presenilin DDE_Tnp_IS1595 PF12762.7 RUS80530.1 - 3e-19 69.5 0.0 5.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain BRX PF08381.11 RUS80530.1 - 0.17 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 PHD PF00628.29 RUS80531.1 - 4.9e-06 26.3 10.3 9.6e-06 25.4 10.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-MYND PF01753.18 RUS80531.1 - 0.0076 16.3 1.9 0.045 13.9 1.9 2.4 1 1 0 1 1 1 1 MYND finger C1_1 PF00130.22 RUS80531.1 - 0.025 14.5 4.3 0.025 14.5 4.3 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RUS80531.1 - 0.025 14.9 9.4 0.049 13.9 5.0 2.3 2 0 0 2 2 2 0 C1 domain DUF5069 PF16798.5 RUS80531.1 - 0.075 13.2 1.9 0.17 12.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) PRP1_N PF06424.12 RUS80531.1 - 0.092 13.1 4.1 0.16 12.4 4.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal BRCA-2_OB1 PF09103.10 RUS80531.1 - 0.097 12.6 0.9 0.25 11.3 0.1 2.1 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Prok-RING_1 PF14446.6 RUS80531.1 - 0.17 11.8 7.3 0.38 10.7 7.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IlvC PF01450.19 RUS80531.1 - 0.2 12.0 2.8 0.4 11.0 0.2 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Phage_holin_3_6 PF07332.11 RUS80532.1 - 0.14 12.2 2.4 0.23 11.5 2.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Folate_rec PF03024.14 RUS80533.1 - 4.4e-16 59.2 12.1 1.7e-15 57.3 12.1 1.8 1 1 0 1 1 1 1 Folate receptor family Fz PF01392.22 RUS80533.1 - 0.045 14.4 10.6 0.84 10.3 10.6 2.2 1 1 0 1 1 1 0 Fz domain MutS_V PF00488.21 RUS80534.1 - 8.5e-68 228.1 0.5 1.9e-67 227.0 0.1 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 RUS80534.1 - 4.8e-21 75.8 1.3 6.3e-21 75.5 0.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 RUS80534.1 - 1.6e-13 51.1 0.1 5e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RUS80534.1 - 2.5e-05 24.5 0.0 0.0026 18.0 0.0 3.1 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 RUS80534.1 - 0.032 14.3 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 RUS80535.1 - 5.2e-25 87.6 1.1 8.8e-25 86.9 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Sox_N PF12444.8 RUS80535.1 - 5.1e-12 46.8 0.3 5.1e-12 46.8 0.3 5.3 4 2 0 4 4 4 1 Sox developmental protein N terminal HMG_box_2 PF09011.10 RUS80535.1 - 1.4e-09 38.4 0.6 2.4e-09 37.6 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain SUIM_assoc PF16619.5 RUS80535.1 - 0.21 11.7 10.2 1.5 8.9 10.2 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Gal-3-0_sulfotr PF06990.11 RUS80536.1 - 6.8e-50 170.1 0.8 1e-49 169.6 0.8 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS80536.1 - 0.004 17.1 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family DERM PF14704.6 RUS80537.1 - 8.9e-45 152.9 6.2 1.1e-44 152.6 6.2 1.0 1 0 0 1 1 1 1 Dermatopontin Myb_DNA-binding PF00249.31 RUS80538.1 - 1.3e-05 25.3 0.1 1.8e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS80538.1 - 7.4e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RUS80538.1 - 0.0015 18.4 0.1 0.0024 17.7 0.1 1.5 1 1 0 1 1 1 1 Myb DNA-binding like Prokineticin PF06607.11 RUS80540.1 - 0.031 14.6 8.4 0.075 13.4 8.4 1.6 1 1 0 1 1 1 0 Prokineticin Colipase_C PF02740.14 RUS80540.1 - 0.092 12.9 1.6 0.092 12.9 1.6 2.4 3 0 0 3 3 3 0 Colipase, C-terminal domain Ras PF00071.22 RUS80541.1 - 7.2e-35 120.0 0.0 1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS80541.1 - 1.2e-21 77.1 0.0 3.2e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS80541.1 - 9.9e-06 25.1 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Bromodomain PF00439.25 RUS80542.1 - 2.5e-17 62.7 0.1 3.8e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 RUS80542.1 - 6.1e-06 26.0 13.0 6.1e-06 26.0 13.0 2.6 2 1 0 2 2 2 1 PHD-finger PWWP PF00855.17 RUS80542.1 - 1.6e-05 25.2 0.4 3.5e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 PWWP domain DUF5402 PF17393.2 RUS80542.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5402) TRAM_LAG1_CLN8 PF03798.16 RUS80543.1 - 2.5e-20 73.1 18.2 2.5e-20 73.1 18.2 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 RUS80543.1 - 3.3e-19 68.3 0.1 8.5e-19 67.0 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein FAA_hydrolase PF01557.18 RUS80544.1 - 1e-57 195.4 0.0 1.3e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 RUS80544.1 - 5.2e-37 126.3 0.0 1e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal EF-hand_7 PF13499.6 RUS80546.1 - 1.6e-08 34.8 9.6 0.12 12.8 0.1 5.5 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_13 PF17958.1 RUS80546.1 - 7.7e-06 25.6 0.0 5.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 RUS80546.1 - 1.7e-05 24.4 4.0 1.6 8.9 0.0 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 RUS80546.1 - 0.023 14.2 1.3 0.68 9.6 0.0 3.8 5 0 0 5 5 5 0 EF hand EF-hand_5 PF13202.6 RUS80546.1 - 0.037 13.5 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 EF hand GPR15L PF15854.5 RUS80547.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 DUF4229 PF14012.6 RUS80547.1 - 6.3 7.0 11.0 1.7 8.8 1.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) TMIE PF16038.5 RUS80547.1 - 7.2 6.5 10.6 0.085 12.7 3.1 1.7 2 0 0 2 2 2 0 TMIE protein Cation_efflux PF01545.21 RUS80548.1 - 4e-24 85.5 11.7 1e-23 84.2 11.7 1.6 1 1 0 1 1 1 1 Cation efflux family 7TMR-DISM_7TM PF07695.11 RUS80548.1 - 2.8 7.8 17.8 0.18 11.7 5.5 2.5 1 1 0 2 2 2 0 7TM diverse intracellular signalling HCR PF07111.12 RUS80549.1 - 3.1e-29 101.7 84.1 3.6e-28 98.1 82.1 2.8 1 1 1 2 2 2 1 Alpha helical coiled-coil rod protein (HCR) HH_signal PF01085.18 RUS80549.1 - 2.6 7.7 9.3 0.28 10.8 0.5 3.0 3 0 0 3 3 3 0 Hedgehog amino-terminal signalling domain E1_DerP2_DerF2 PF02221.15 RUS80550.1 - 4.2e-25 88.7 1.2 6.2e-25 88.2 1.2 1.3 1 0 0 1 1 1 1 ML domain DUF4497 PF14924.6 RUS80551.1 - 6.8e-20 71.5 0.1 2.3e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) HPHLAWLY PF14925.6 RUS80551.1 - 7.8e-05 21.6 3.1 7.8e-05 21.6 3.1 3.4 3 1 1 4 4 4 2 Domain of unknown function COX6B PF02297.17 RUS80552.1 - 5.8e-17 61.7 11.9 6.7e-17 61.5 11.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 RUS80552.1 - 0.001 19.4 5.2 0.0023 18.2 5.2 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 RUS80552.1 - 0.0046 16.9 5.6 0.0085 16.1 5.6 1.6 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2509 PF10713.9 RUS80552.1 - 0.021 14.9 1.7 0.025 14.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) CHCH PF06747.13 RUS80552.1 - 0.023 14.8 6.3 0.049 13.8 6.1 1.7 1 1 0 1 1 1 0 CHCH domain Sds3 PF08598.11 RUS80553.1 - 2.1e-15 57.3 12.6 2.1e-15 57.3 12.6 2.6 2 1 1 3 3 3 2 Sds3-like DASH_Dad3 PF08656.10 RUS80553.1 - 0.22 11.6 4.9 0.19 11.9 0.5 2.7 2 2 0 2 2 2 0 DASH complex subunit Dad3 Ribosomal_L29 PF00831.23 RUS80553.1 - 2.1 8.4 9.8 5 7.2 5.4 3.5 2 1 0 2 2 2 0 Ribosomal L29 protein MerR-DNA-bind PF09278.11 RUS80553.1 - 2.5 8.7 8.2 1.1 9.8 0.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding 2OG-FeII_Oxy_2 PF13532.6 RUS80554.1 - 1.4e-15 58.0 0.0 3e-14 53.7 0.0 1.9 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ribonuclease_3 PF00636.26 RUS80555.1 - 2e-58 195.5 0.0 4.7e-33 114.0 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 RUS80555.1 - 2.8e-38 130.8 0.1 7e-38 129.5 0.1 1.7 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 RUS80555.1 - 4.6e-26 90.8 0.1 1.4e-25 89.2 0.1 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 RUS80555.1 - 3.9e-22 78.8 0.1 4.7e-15 55.9 0.1 4.4 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 RUS80555.1 - 5.6e-13 49.2 0.0 1.5e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 RUS80555.1 - 7.3e-05 23.4 0.5 0.036 14.8 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 RUS80555.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Aminotran_1_2 PF00155.21 RUS80557.1 - 5.7e-57 193.5 0.0 6.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS80557.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF992 PF06186.11 RUS80557.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) DUF4304 PF14137.6 RUS80559.1 - 0.18 12.0 0.7 0.48 10.6 0.1 2.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4304) ERG4_ERG24 PF01222.17 RUS80560.1 - 1.7e-32 112.8 14.8 1.8e-32 112.6 14.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 RUS80560.1 - 8.5e-08 32.0 4.5 1.1e-07 31.6 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RUS80560.1 - 0.0034 17.4 3.7 0.0064 16.5 3.7 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RUS80560.1 - 0.013 15.9 3.4 0.013 15.9 3.4 2.1 2 1 0 2 2 2 0 Phospholipid methyltransferase DUF3708 PF12501.8 RUS80560.1 - 0.041 13.7 0.6 0.041 13.7 0.6 1.7 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter ERG4_ERG24 PF01222.17 RUS80561.1 - 1.5e-143 478.7 12.0 2.7e-143 477.8 12.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 RUS80561.1 - 0.0032 17.0 0.1 0.0081 15.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 RUS80561.1 - 0.022 15.1 2.2 0.049 14.0 0.0 2.6 3 0 0 3 3 3 0 Phospholipid methyltransferase Josephin PF02099.17 RUS80562.1 - 1.3e-53 181.5 1.3 1.4e-53 181.3 0.1 1.7 2 0 0 2 2 2 1 Josephin UIM PF02809.20 RUS80562.1 - 6.6e-08 31.9 8.1 0.0015 18.3 0.9 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif Gti1_Pac2 PF09729.9 RUS80562.1 - 0.048 13.8 1.0 4 7.5 0.6 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family RAP80_UIM PF18282.1 RUS80562.1 - 0.24 11.2 3.8 0.58 10.0 1.6 2.6 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif UCH PF00443.29 RUS80564.1 - 4.5e-29 101.7 0.2 4.8e-26 91.8 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 RUS80564.1 - 4.9e-05 23.6 6.5 4.9e-05 23.6 6.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RUS80564.1 - 0.0064 16.3 6.3 0.033 14.1 6.3 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS80564.1 - 0.0065 16.5 3.4 0.0097 15.9 0.5 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS80564.1 - 0.062 13.5 7.4 0.25 11.5 7.4 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS80564.1 - 0.61 10.0 12.0 0.13 12.2 7.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RUS80564.1 - 0.85 9.5 4.3 4.3 7.3 4.3 2.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 RUS80564.1 - 0.97 9.4 13.1 0.078 13.0 5.6 3.0 3 0 0 3 3 3 0 zinc-RING finger domain Ank_2 PF12796.7 RUS80566.1 - 3.8e-25 88.3 4.3 5.2e-13 49.4 0.4 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS80566.1 - 1e-19 70.6 0.2 6.3e-08 33.0 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS80566.1 - 2.7e-16 59.2 0.2 0.13 12.7 0.0 5.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RUS80566.1 - 1.1e-12 46.9 0.0 1 10.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 RUS80566.1 - 1.3e-12 47.7 1.0 3.9e-06 27.0 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) PMI_typeI PF01238.21 RUS80567.1 - 5.7e-116 387.8 0.0 6.8e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RUS80567.1 - 0.18 11.5 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain DUF945 PF06097.11 RUS80568.1 - 0.055 12.6 0.8 3.5 6.6 0.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF945) Suv3_N PF18114.1 RUS80568.1 - 0.074 13.2 14.6 1.3 9.2 1.1 4.5 1 1 2 4 4 4 0 Suv3 helical N-terminal domain Crl PF07417.12 RUS80568.1 - 0.28 11.2 4.6 17 5.5 0.2 3.5 1 1 3 4 4 4 0 Sigma factor-binding transcriptional regulator Crl RA PF00788.23 RUS80568.1 - 1.5 9.5 7.8 1.8e+02 2.9 0.0 5.8 1 1 4 5 5 5 0 Ras association (RalGDS/AF-6) domain Pox_A_type_inc PF04508.12 RUS80568.1 - 4.8 7.2 33.3 5.3e+02 0.7 0.0 14.9 19 0 0 19 19 19 0 Viral A-type inclusion protein repeat GXGXG PF01493.19 RUS80571.1 - 0.028 14.0 2.9 1 9.0 0.9 2.4 1 1 1 2 2 2 0 GXGXG motif Ribosomal_L6 PF00347.23 RUS80571.1 - 0.99 10.1 6.0 4.6 8.0 0.6 2.7 1 1 1 2 2 2 0 Ribosomal protein L6 MFS_1 PF07690.16 RUS80572.1 - 5.8e-27 94.5 35.4 7.3e-27 94.2 35.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SCHIP-1 PF10148.9 RUS80573.1 - 0.0055 16.4 0.1 0.0089 15.7 0.1 1.4 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 IQ PF00612.27 RUS80575.1 - 7.6e-08 31.5 11.3 0.0001 21.8 0.4 3.1 2 1 1 3 3 3 2 IQ calmodulin-binding motif IQCJ-SCHIP1 PF15157.6 RUS80575.1 - 0.038 13.8 1.4 0.038 13.8 1.4 1.6 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Voldacs PF03517.13 RUS80576.1 - 1.1e-26 93.6 0.1 2.7e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling SNF2_N PF00176.23 RUS80578.1 - 2e-61 207.7 0.0 3.5e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS80578.1 - 3.1e-17 62.9 0.0 7.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS80578.1 - 1.6e-08 34.7 0.0 4.9e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RUS80578.1 - 0.0012 18.6 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 RUS80578.1 - 0.0082 16.5 0.0 0.025 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 RUS80578.1 - 0.03 14.0 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase WD40 PF00400.32 RUS80581.1 - 5.7e-07 30.1 0.0 0.0085 16.9 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat EF-hand_8 PF13833.6 RUS80581.1 - 0.00058 19.7 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS80581.1 - 0.0034 17.2 0.2 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RUS80581.1 - 0.0039 17.6 0.1 0.0083 16.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS80581.1 - 0.18 11.4 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 EF hand OB_NTP_bind PF07717.16 RUS80582.1 - 1.1e-23 83.3 0.0 2.2e-23 82.4 0.0 1.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Ribonuc_P_40 PF08584.11 RUS80583.1 - 1.3e-68 231.4 0.0 2.7e-68 230.3 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_pol_A_bac PF01000.26 RUS80584.1 - 8.6e-39 132.4 0.0 1.4e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RUS80584.1 - 6.2e-19 67.2 0.0 8.9e-19 66.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 RUS80585.1 - 3.8e-05 23.2 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UPF0524 PF15823.5 RUS80585.1 - 0.03 13.7 0.1 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 CREPT PF16566.5 RUS80586.1 - 3.9e-58 195.8 3.2 9.8e-58 194.5 3.2 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 RUS80586.1 - 6.6e-21 74.9 0.3 3.4e-20 72.6 0.0 2.4 2 1 1 3 3 3 1 RNA polymerase II-binding domain. CTK3 PF12243.8 RUS80586.1 - 2e-05 24.6 0.2 4.6e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF4763 PF15960.5 RUS80586.1 - 0.08 12.2 5.4 0.17 11.1 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) UPF0113_N PF17833.1 RUS80586.1 - 0.17 12.5 1.3 0.24 12.0 0.3 1.8 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain RsbRD_N PF14361.6 RUS80586.1 - 2.2 9.0 6.6 5.8 7.7 0.0 3.0 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain CENP-H PF05837.12 RUS80586.1 - 5.7 7.4 12.3 0.22 11.9 3.4 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) CpeT PF06206.11 RUS80587.1 - 2.2e-10 40.8 0.1 2.6e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) SNAP PF14938.6 RUS80588.1 - 4.5e-26 91.9 12.4 5.8e-26 91.6 12.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 RUS80588.1 - 4.6e-09 36.1 1.5 6.9e-09 35.5 1.5 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 RUS80588.1 - 1.2e-08 35.1 6.2 5.5e-05 23.4 0.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80588.1 - 0.00085 19.3 15.3 1.6 9.1 0.5 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 RUS80588.1 - 0.0012 19.5 0.9 3.9 8.3 0.0 3.2 2 0 0 2 2 2 2 Sel1 repeat TPR_2 PF07719.17 RUS80588.1 - 0.0033 17.4 20.0 1 9.7 1.2 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF4365 PF14280.6 RUS80588.1 - 0.0036 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4365) TPR_1 PF00515.28 RUS80588.1 - 0.0051 16.6 16.1 3 7.8 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat RasGEF_N_2 PF14663.6 RUS80588.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DHR-2 PF06920.13 RUS80588.1 - 0.015 13.9 4.1 0.022 13.4 2.0 1.7 1 1 1 2 2 2 0 Dock homology region 2 TPR_7 PF13176.6 RUS80588.1 - 0.02 14.9 6.4 1.4 9.1 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 RUS80588.1 - 1.2 9.3 16.6 0.33 11.0 0.3 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 RUS80588.1 - 1.6 9.0 10.9 0.7 10.2 1.4 3.5 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4810 PF16068.5 RUS80588.1 - 2 9.0 7.3 0.85 10.2 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) TPR_6 PF13174.6 RUS80588.1 - 3.8 8.4 8.5 1.1e+02 3.7 0.7 5.6 6 2 1 7 7 6 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 RUS80589.1 - 1.1e-35 122.9 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS80589.1 - 5.7e-12 46.0 0.0 7.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RUS80589.1 - 6.8e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 RUS80589.1 - 7.1e-06 25.7 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 RUS80589.1 - 0.031 14.8 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 MapZ_C2 PF18708.1 RUS80589.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 MapZ extracellular C-terminal domain 2 Glyco_transf_4 PF13439.6 RUS80589.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 B12-binding PF02310.19 RUS80589.1 - 0.17 11.9 0.0 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain Beach PF02138.18 RUS80590.1 - 3.5e-110 367.7 0.0 5.7e-110 367.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RUS80590.1 - 7e-09 35.7 0.6 3.4e-06 27.1 0.1 3.3 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH GRAM PF02893.20 RUS80590.1 - 0.0016 18.3 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 RUS80590.1 - 0.02 15.2 0.0 6.6 7.1 0.0 2.6 2 1 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Ldl_recept_a PF00057.18 RUS80591.1 - 1.5e-08 34.7 11.3 4.1e-08 33.3 11.3 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Cupin_8 PF13621.6 RUS80592.1 - 3.4e-43 148.2 0.4 3.4e-43 148.2 0.4 1.4 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 RUS80592.1 - 2.5e-12 46.9 0.8 4.4e-12 46.1 0.8 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 RUS80592.1 - 8e-05 23.0 0.0 0.00027 21.3 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RUS80592.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain LRR_8 PF13855.6 RUS80593.1 - 0.017 14.9 0.2 0.16 11.7 0.2 2.6 2 1 0 2 2 2 0 Leucine rich repeat TIR PF01582.20 RUS80594.1 - 8.8e-21 74.5 0.1 1.4e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS80594.1 - 1.3e-16 61.3 0.0 2.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 RUS80594.1 - 9.1e-06 25.3 1.7 0.0018 18.0 0.5 2.9 2 1 1 3 3 3 2 Leucine rich repeat DUF1863 PF08937.11 RUS80594.1 - 3.8e-05 24.0 0.0 8.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 RUS80594.1 - 0.00029 20.6 0.0 0.034 14.2 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 RUS80594.1 - 0.021 15.3 1.9 0.54 10.8 0.0 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRRCT PF01463.24 RUS80594.1 - 0.059 13.9 0.0 0.31 11.7 0.0 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 RUS80594.1 - 1.2 9.9 3.1 5.7 7.9 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat HHH_3 PF12836.7 RUS80596.1 - 4.9e-36 122.8 0.0 8.1e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 RUS80596.1 - 3.4e-12 45.6 0.2 1.3e-06 27.9 0.0 4.4 4 0 0 4 4 4 2 Helix-hairpin-helix motif HHH_6 PF14579.6 RUS80596.1 - 1.1e-07 32.0 0.0 9e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 RUS80596.1 - 3.1e-05 23.5 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K HHH_2 PF12826.7 RUS80596.1 - 4.4e-05 23.5 0.0 0.02 15.0 0.0 3.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 RUS80596.1 - 5.6e-05 23.7 1.7 0.58 10.8 0.0 4.6 4 1 1 5 5 5 1 Helix-hairpin-helix domain PsbU PF06514.11 RUS80596.1 - 0.0079 16.2 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) Glucos_trans_II PF14264.6 RUS80596.1 - 0.041 13.3 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII ETM PF17577.2 RUS80596.1 - 0.083 13.5 2.3 9.4 6.9 0.3 2.6 2 0 0 2 2 2 0 ECORI-T site Dicty_CAR PF05462.11 RUS80597.1 - 4.5e-16 58.8 14.3 6.1e-16 58.4 14.3 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 RUS80597.1 - 5.5e-08 32.8 1.5 6e-07 29.4 0.0 3.0 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term TadE PF07811.12 RUS80597.1 - 3.4 8.0 4.9 0.46 10.8 0.4 1.9 2 0 0 2 2 2 0 TadE-like protein DUF1449 PF07290.11 RUS80597.1 - 4.4 6.9 6.9 7.6 6.1 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) CD36 PF01130.21 RUS80598.1 - 8.3e-141 469.7 2.1 1e-140 469.4 2.1 1.1 1 0 0 1 1 1 1 CD36 family DUF3040 PF11239.8 RUS80598.1 - 0.23 11.7 0.9 3 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) zf-C2H2_4 PF13894.6 RUS80599.1 - 9.2e-20 69.6 128.8 0.0018 19.0 0.7 15.0 15 0 0 15 15 15 11 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS80599.1 - 1.9e-12 46.9 135.5 0.0002 21.7 0.7 14.7 15 0 0 15 15 15 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS80599.1 - 9.3e-11 41.6 106.3 6.4e-05 23.2 0.8 13.5 13 2 0 13 13 13 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS80599.1 - 4.3e-06 26.9 76.0 0.022 15.0 0.2 12.2 11 1 0 11 11 11 6 Zinc-finger double-stranded RNA-binding DUF951 PF06107.11 RUS80599.1 - 0.0077 16.1 0.1 0.0077 16.1 0.1 4.2 5 1 0 5 5 5 1 Bacterial protein of unknown function (DUF951) zf-C2H2_11 PF16622.5 RUS80599.1 - 0.012 15.4 0.2 0.012 15.4 0.2 10.4 11 0 0 11 11 11 0 zinc-finger C2H2-type zf-met PF12874.7 RUS80599.1 - 0.025 15.0 0.3 0.025 15.0 0.3 12.5 13 1 1 14 14 14 0 Zinc-finger of C2H2 type BolA PF01722.18 RUS80599.1 - 0.058 13.7 8.3 7.3 6.9 0.1 5.2 3 2 1 4 4 4 0 BolA-like protein CAS_C PF12026.8 RUS80601.1 - 4.2e-55 187.1 2.8 7.1e-54 183.1 2.8 2.4 1 1 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 RUS80601.1 - 7.4e-43 146.3 3.9 1.3e-42 145.5 3.9 1.4 1 0 0 1 1 1 1 Serine rich protein interaction domain SH3_9 PF14604.6 RUS80601.1 - 1.2e-10 41.1 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS80601.1 - 4.3e-09 35.8 0.0 7.9e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS80601.1 - 2.9e-08 33.3 0.0 5.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TBK1_CCD1 PF18394.1 RUS80601.1 - 0.014 14.9 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Gln-synt_C PF00120.24 RUS80602.1 - 1.1e-65 221.9 0.0 2.1e-65 221.0 0.0 1.4 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.24 RUS80603.1 - 1.3e-32 113.2 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Ribosomal_L13e PF01294.18 RUS80604.1 - 7.3e-77 257.3 5.4 9.3e-77 256.9 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Alpha_kinase PF02816.18 RUS80606.1 - 1.2e-26 93.9 0.0 1.8e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family TFR_dimer PF04253.15 RUS80607.1 - 5.8e-20 71.6 0.0 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RUS80607.1 - 6.2e-10 39.1 0.0 1.6e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 DUF3328 PF11807.8 RUS80608.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ATP_bind_1 PF03029.17 RUS80609.1 - 2e-83 279.9 0.1 2.3e-83 279.7 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 RUS80609.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 RUS80609.1 - 0.00063 19.4 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 RUS80609.1 - 0.00072 19.3 0.1 0.0019 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 RUS80609.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 RUS80609.1 - 0.0028 17.6 0.2 0.032 14.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 RUS80609.1 - 0.0044 16.2 0.0 0.0094 15.2 0.0 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_33 PF13671.6 RUS80609.1 - 0.0085 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS80609.1 - 0.014 15.9 0.1 0.066 13.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 RUS80609.1 - 0.016 15.6 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 RUS80609.1 - 0.017 15.5 0.1 0.038 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 RUS80609.1 - 0.019 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 RUS80609.1 - 0.031 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 RUS80609.1 - 0.034 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 RUS80609.1 - 0.063 12.9 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RUS80609.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RUS80609.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Phage_Capsid_P3 PF09018.11 RUS80609.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 P3 major capsid protein RNA_helicase PF00910.22 RUS80609.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CBP_BcsQ PF06564.12 RUS80609.1 - 0.14 11.6 0.1 0.99 8.8 0.1 2.3 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ NTPase_1 PF03266.15 RUS80609.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 RUS80609.1 - 0.19 12.1 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 RUS80609.1 - 0.2 11.0 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GRIP PF01465.20 RUS80610.1 - 1.1e-09 38.0 0.1 4e-09 36.2 0.1 2.1 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 RUS80610.1 - 0.00037 19.9 33.4 0.00037 19.9 33.4 19.5 2 1 16 19 19 19 1 Growth-arrest specific micro-tubule binding FAM184 PF15665.5 RUS80610.1 - 0.00089 19.1 43.7 0.00089 19.1 43.7 18.2 3 1 13 17 17 17 5 Family with sequence similarity 184, A and B PRIMA1 PF16101.5 RUS80611.1 - 0.48 10.5 11.9 0.49 10.5 7.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FUSC PF04632.12 RUS80611.1 - 2.5 6.6 10.1 1.9 6.9 0.2 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family FPP PF05911.11 RUS80611.1 - 4.1 5.5 48.5 0.0055 15.0 31.0 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil PMC2NT PF08066.12 RUS80611.1 - 8.5 7.1 11.8 3.4 8.4 0.7 4.2 2 1 2 4 4 4 0 PMC2NT (NUC016) domain zf-B_box PF00643.24 RUS80612.1 - 2.2e-08 34.1 2.9 2.2e-08 34.1 2.9 3.0 4 0 0 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.6 RUS80612.1 - 9.6e-08 31.9 4.8 9.6e-08 31.9 4.8 2.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS80612.1 - 1.4e-07 31.4 7.0 1.4e-07 31.4 7.0 2.9 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS80612.1 - 1.8e-06 27.7 10.0 1.8e-06 27.7 10.0 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS80612.1 - 1.5e-05 25.0 2.8 1.5e-05 25.0 2.8 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS80612.1 - 1.9e-05 24.4 4.4 1.9e-05 24.4 4.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS80612.1 - 2.2e-05 24.7 11.4 2.2e-05 24.7 11.4 3.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS80612.1 - 0.0012 18.6 4.0 0.0012 18.6 4.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 RUS80612.1 - 0.0078 15.1 6.5 0.019 13.9 6.7 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein zinc_ribbon_5 PF13719.6 RUS80612.1 - 0.016 14.9 1.5 0.33 10.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_11 PF17123.5 RUS80612.1 - 0.025 14.3 4.8 0.078 12.7 4.8 1.9 1 0 0 1 1 1 0 RING-like zinc finger ArnB_C PF18677.1 RUS80612.1 - 0.025 14.7 3.1 0.053 13.6 3.1 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain FlgN PF05130.12 RUS80612.1 - 0.76 10.3 7.1 1.3 9.5 7.1 1.4 1 0 0 1 1 1 0 FlgN protein Prok-RING_4 PF14447.6 RUS80612.1 - 2 8.4 25.4 2.9 7.8 4.1 4.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS80613.1 - 2.2e-08 34.0 2.0 2.2e-08 34.0 2.0 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 RUS80613.1 - 5.9e-08 32.7 7.8 5.9e-08 32.7 7.8 2.7 3 0 0 3 3 3 1 B-box zinc finger zf-RING_5 PF14634.6 RUS80613.1 - 7.4e-06 25.8 6.4 7.4e-06 25.8 6.4 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS80613.1 - 5.1e-05 23.0 7.1 5.1e-05 23.0 7.1 3.1 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS80613.1 - 0.00057 20.2 11.1 0.00057 20.2 11.1 3.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS80613.1 - 0.0016 18.3 5.3 0.0016 18.3 5.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2616 PF11077.8 RUS80613.1 - 0.026 14.3 10.6 0.56 9.9 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) zf-C3HC4_4 PF15227.6 RUS80613.1 - 0.028 14.6 2.7 0.028 14.6 2.7 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING RRF PF01765.19 RUS80613.1 - 0.052 13.5 4.0 0.11 12.5 4.0 1.5 1 0 0 1 1 1 0 Ribosome recycling factor DUF3583 PF12126.8 RUS80613.1 - 0.058 12.9 3.2 0.092 12.2 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF4795 PF16043.5 RUS80613.1 - 0.062 12.9 7.8 0.14 11.7 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ApoLp-III PF07464.11 RUS80613.1 - 0.071 13.2 1.6 0.33 11.1 1.3 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RsbRD_N PF14361.6 RUS80613.1 - 0.16 12.6 1.8 0.35 11.6 1.8 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF148 PF02520.17 RUS80613.1 - 0.44 10.7 3.9 2.2 8.4 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Spc7 PF08317.11 RUS80613.1 - 3.8 6.3 13.5 0.1 11.4 7.4 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 RUS80613.1 - 4.9 7.5 8.8 0.99 9.7 4.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RIG-I_C-RD PF11648.8 RUS80613.1 - 6 7.1 12.5 0.69 10.2 3.5 2.6 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-B_box PF00643.24 RUS80615.1 - 3.5e-07 30.2 3.1 5.6e-07 29.6 3.1 1.3 1 0 0 1 1 1 1 B-box zinc finger DUF4795 PF16043.5 RUS80615.1 - 0.0098 15.5 8.1 0.047 13.3 0.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) DUF3583 PF12126.8 RUS80615.1 - 0.016 14.7 3.0 0.023 14.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Spc7 PF08317.11 RUS80615.1 - 0.017 14.0 7.4 0.023 13.6 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RRF PF01765.19 RUS80615.1 - 0.017 15.1 4.0 0.033 14.2 4.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor ApoLp-III PF07464.11 RUS80615.1 - 0.018 15.1 2.0 0.14 12.3 1.2 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RsbRD_N PF14361.6 RUS80615.1 - 0.051 14.3 1.6 0.083 13.6 1.6 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Mitofilin PF09731.9 RUS80615.1 - 0.057 12.3 6.3 0.066 12.1 6.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein STAT_alpha PF01017.20 RUS80615.1 - 0.075 12.9 2.0 0.12 12.3 2.0 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain Aldedh PF00171.22 RUS80615.1 - 0.093 11.2 0.7 0.12 10.9 0.7 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Allexi_40kDa PF05549.11 RUS80615.1 - 0.1 12.1 1.8 0.28 10.6 1.8 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Apolipoprotein PF01442.18 RUS80615.1 - 0.13 12.1 6.4 0.29 11.0 6.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS80615.1 - 0.15 12.1 1.0 0.43 10.6 1.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 RUS80615.1 - 0.16 12.6 5.1 0.45 11.2 5.1 1.8 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_2 PF01920.20 RUS80615.1 - 0.2 11.7 7.3 0.34 10.9 7.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF4407 PF14362.6 RUS80615.1 - 0.29 10.5 3.1 0.38 10.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 RUS80615.1 - 0.36 10.0 1.6 0.5 9.6 1.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 RUS80615.1 - 0.41 10.7 2.5 0.74 9.9 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) K-box PF01486.17 RUS80615.1 - 0.73 10.0 5.8 11 6.3 0.4 2.4 2 0 0 2 2 2 0 K-box region OmpH PF03938.14 RUS80615.1 - 0.99 9.7 7.8 2.3 8.6 7.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 RUS80615.1 - 1 8.3 5.2 2 7.4 4.7 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MerR-DNA-bind PF09278.11 RUS80615.1 - 1.9 9.1 6.3 9.4 6.9 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding RVT_1 PF00078.27 RUS80616.1 - 0.0038 16.8 0.8 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3157 PF11355.8 RUS80617.1 - 0.17 11.5 0.1 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) zf-CXXC PF02008.20 RUS80617.1 - 2.1 8.5 12.2 0.45 10.6 4.5 2.5 1 1 1 2 2 2 0 CXXC zinc finger domain PAN_1 PF00024.26 RUS80618.1 - 8.8e-05 22.4 0.4 0.00017 21.5 0.4 1.4 1 0 0 1 1 1 1 PAN domain Tetraspanin PF00335.20 RUS80619.1 - 2.4e-38 132.1 6.9 3e-38 131.8 6.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 RUS80619.1 - 0.0093 16.2 0.6 0.0093 16.2 0.6 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4064) S_4TM PF18159.1 RUS80619.1 - 0.65 9.2 5.6 5.6 6.2 0.1 2.3 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF2721 PF11026.8 RUS80619.1 - 3.8 7.4 8.7 0.86 9.5 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MFS_2 PF13347.6 RUS80621.1 - 6e-37 127.2 16.5 9.7e-37 126.5 16.5 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 RUS80621.1 - 1.9e-13 50.1 17.7 2.5e-13 49.7 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 RUS80621.1 - 0.062 13.6 0.1 3.4 8.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Kinesin PF00225.23 RUS80622.1 - 1.3e-101 339.9 1.1 1.3e-101 339.9 1.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS80622.1 - 1.3e-44 151.7 0.8 4.1e-44 150.1 0.8 2.0 1 0 0 1 1 1 1 Microtubule binding SMC_N PF02463.19 RUS80623.1 - 3e-57 193.6 44.7 9.7e-57 191.9 44.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RUS80623.1 - 3.8e-21 75.6 0.0 1e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 RUS80623.1 - 8.8e-14 52.5 22.0 8.8e-14 52.5 22.0 7.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 RUS80623.1 - 1.8e-12 47.7 9.6 1.6e-06 28.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RUS80623.1 - 3.6e-05 23.7 82.5 6.5e-05 22.8 37.9 4.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RUS80623.1 - 0.0027 17.4 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain YabA PF06156.13 RUS80623.1 - 0.0061 17.2 5.7 0.0061 17.2 5.7 8.8 3 3 7 10 10 10 1 Initiation control protein YabA OmpH PF03938.14 RUS80623.1 - 0.0077 16.6 12.3 0.0077 16.6 12.3 8.7 3 2 4 7 7 7 1 Outer membrane protein (OmpH-like) ABC_tran PF00005.27 RUS80623.1 - 0.42 11.1 0.0 0.42 11.1 0.0 7.3 4 2 1 5 5 5 0 ABC transporter Y_Y_Y PF07495.13 RUS80625.1 - 0.0042 17.0 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Y_Y_Y domain LSM PF01423.22 RUS80626.1 - 2.1e-20 72.1 0.0 3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Nop14 PF04147.12 RUS80626.1 - 0.00012 20.5 22.5 0.00014 20.2 22.5 1.0 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 RUS80626.1 - 0.12 10.4 47.8 0.16 10.0 47.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS80626.1 - 0.33 9.2 25.4 0.45 8.7 25.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 RUS80626.1 - 0.48 9.8 25.6 0.68 9.3 25.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 RUS80626.1 - 1.4 7.3 23.7 1.9 6.9 23.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop25 PF09805.9 RUS80626.1 - 2.5 8.6 12.7 3.8 8.0 12.7 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) IFT57 PF10498.9 RUS80626.1 - 3.2 6.6 10.3 5.4 5.9 10.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 eIF-3c_N PF05470.12 RUS80626.1 - 4.1 5.6 13.6 6.1 5.0 13.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAPS PF04499.15 RUS80626.1 - 5.9 5.6 9.1 7 5.3 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS80626.1 - 7.1 6.0 35.7 9.7 5.5 35.7 1.1 1 0 0 1 1 1 0 SDA1 AsmA_2 PF13502.6 RUS80628.1 - 0.096 12.2 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 AsmA-like C-terminal region CCDC24 PF15669.5 RUS80629.1 - 1.5 8.6 4.5 2.8 7.8 4.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Glutaredoxin PF00462.24 RUS80630.1 - 1.8e-16 60.1 0.1 2.9e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.6 RUS80630.1 - 0.037 14.2 0.2 4.2 7.5 0.2 2.2 1 1 0 2 2 2 0 Thioredoxin DUF836 PF05768.14 RUS80630.1 - 0.064 13.7 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 RUS80630.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin PAS_11 PF14598.6 RUS80631.1 - 1.6e-27 95.8 0.4 1.1e-23 83.5 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 RUS80631.1 - 7.4e-21 74.3 0.0 1.9e-12 47.3 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 RUS80631.1 - 2.1e-17 63.1 0.0 5.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 RUS80631.1 - 3.1e-16 59.1 2.1 6.4e-16 58.1 2.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 RUS80631.1 - 1.6e-09 38.0 0.0 4.6e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 RUS80631.1 - 4e-05 23.8 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 RUS80631.1 - 0.0018 18.9 0.0 0.018 15.7 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 RUS80631.1 - 0.0076 16.3 0.0 0.038 14.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAW PF04721.17 RUS80632.1 - 8.6e-63 211.7 0.7 1.4e-62 211.0 0.0 1.7 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 RUS80632.1 - 6e-21 74.2 0.1 1.3e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 RUS80632.1 - 5.4e-15 55.8 0.4 1.3e-14 54.6 0.4 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 RUS80632.1 - 8.6e-09 35.2 1.2 1.8e-08 34.2 1.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Med27 PF11571.8 RUS80632.1 - 0.011 16.0 0.0 0.051 13.9 0.0 2.1 1 1 0 1 1 1 0 Mediator complex subunit 27 PHR PF08005.12 RUS80633.1 - 2.2e-25 90.1 0.1 4.2e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 RUS80633.1 - 4e-16 59.2 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS80633.1 - 3.5e-07 30.3 1.0 4.9e-05 23.4 0.2 2.5 2 0 0 2 2 2 2 BTB And C-terminal Kelch NAGLU_N PF12971.7 RUS80634.1 - 0.031 14.1 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain WH2 PF02205.20 RUS80635.1 - 7.2e-12 44.7 1.7 1.5e-11 43.7 1.7 1.6 1 0 0 1 1 1 1 WH2 motif Pkinase PF00069.25 RUS80635.1 - 0.0022 17.4 0.1 0.018 14.5 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Orthoreo_P10 PF07204.11 RUS80635.1 - 0.097 12.6 1.0 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF3487 PF11990.8 RUS80635.1 - 0.2 11.6 1.0 0.75 9.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) L51_S25_CI-B8 PF05047.16 RUS80636.1 - 2.3e-06 27.4 0.1 9.1e-06 25.5 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TILa PF12714.7 RUS80636.1 - 0.031 14.2 1.2 0.065 13.2 1.2 1.5 1 0 0 1 1 1 0 TILa domain FYVE PF01363.21 RUS80637.1 - 5.6e-20 71.2 3.6 1.3e-19 70.1 3.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 RUS80637.1 - 2.1e-15 56.2 1.8 5.6e-15 54.8 1.8 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 RUS80637.1 - 0.0012 19.1 1.5 0.0017 18.6 0.1 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 RUS80637.1 - 0.031 14.1 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 RUS80637.1 - 0.6 11.1 0.1 0.6 11.1 0.1 3.6 3 1 1 4 4 4 0 C2H2-type zinc finger Fibrinogen_C PF00147.18 RUS80638.1 - 4.3e-45 154.2 0.1 7.1e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS80638.1 - 6e-08 32.8 3.5 1.2e-07 31.8 3.5 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2780 PF11075.8 RUS80638.1 - 0.0014 18.8 1.9 0.0025 18.0 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Baculo_PEP_C PF04513.12 RUS80638.1 - 0.0023 18.0 0.9 0.0023 18.0 0.9 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF842 PF05811.13 RUS80638.1 - 0.0057 16.3 0.8 3.7 7.3 0.2 3.0 1 1 2 3 3 3 1 Eukaryotic protein of unknown function (DUF842) Sds3 PF08598.11 RUS80638.1 - 0.039 14.0 4.7 0.47 10.4 5.1 1.9 1 1 1 2 2 2 0 Sds3-like Exonuc_VII_L PF02601.15 RUS80638.1 - 0.089 12.3 2.5 0.15 11.6 2.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 RUS80638.1 - 0.18 11.8 2.8 1.3 9.1 1.3 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4164 PF13747.6 RUS80638.1 - 0.46 10.8 7.9 0.14 12.4 1.9 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) HrpJ PF07201.11 RUS80638.1 - 1 9.6 5.6 4.8 7.5 2.5 2.4 1 1 0 2 2 2 0 HrpJ-like domain Prominin PF05478.11 RUS80638.1 - 1.1 7.1 6.3 1.6 6.6 6.3 1.1 1 0 0 1 1 1 0 Prominin Sipho_Gp157 PF05565.11 RUS80638.1 - 3.9 7.4 6.2 2.2 8.3 1.3 2.4 1 1 2 3 3 3 0 Siphovirus Gp157 NPV_P10 PF05531.12 RUS80638.1 - 6.1 7.4 7.8 3e+02 2.0 7.8 3.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 RUS80638.1 - 6.3 6.2 8.7 10 5.6 2.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 RUS80638.1 - 9.6 6.4 7.0 47 4.1 6.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SKI PF01202.22 RUS80639.1 - 2.9e-25 89.2 0.0 5.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase PALP PF00291.25 RUS80639.1 - 3.5e-11 43.1 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 RUS80639.1 - 3.2e-10 40.1 0.0 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus AAA_18 PF13238.6 RUS80639.1 - 1.6e-05 25.5 0.0 3.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS80639.1 - 0.00024 21.4 0.0 0.0034 17.7 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 RUS80639.1 - 0.00094 19.6 0.0 0.0023 18.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS80639.1 - 0.0054 17.1 0.0 0.017 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RUS80639.1 - 0.012 15.8 0.3 0.051 13.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RUS80639.1 - 0.017 15.6 0.0 2.3 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RUS80639.1 - 0.027 13.9 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS80639.1 - 0.08 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 RUS80639.1 - 0.085 12.5 0.0 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_M PF01031.20 RUS80640.1 - 6.2e-103 343.9 0.6 1.2e-102 343.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 RUS80640.1 - 2.1e-52 177.6 1.6 4.1e-52 176.6 0.0 2.3 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 RUS80640.1 - 6e-32 109.7 4.5 2.2e-31 107.8 4.5 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 RUS80640.1 - 4.5e-05 23.5 0.2 0.00033 20.7 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS80640.1 - 0.0024 18.3 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NUC202 PF08166.12 RUS80640.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 NUC202 domain AAA_21 PF13304.6 RUS80640.1 - 0.09 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 RUS80640.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RUS80640.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain MRP-S33 PF08293.11 RUS80641.1 - 2.8e-19 69.2 1.2 3.4e-19 68.9 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 HycH PF07450.11 RUS80643.1 - 0.0027 18.1 12.6 5.3 7.4 0.1 5.4 1 1 4 5 5 5 3 Formate hydrogenlyase maturation protein HycH Strep_his_triad PF04270.13 RUS80643.1 - 0.027 14.5 3.8 19 5.3 0.2 4.5 1 1 5 6 6 6 0 Streptococcal histidine triad protein HemeBinding_Shp PF11545.8 RUS80643.1 - 0.16 11.9 2.8 9.8 6.1 0.4 2.3 1 1 0 2 2 2 0 Cell surface heme-binding protein Shp AsnC_trans_reg PF01037.21 RUS80643.1 - 0.21 11.6 1.0 14 5.7 0.2 2.6 1 1 2 3 3 3 0 Lrp/AsnC ligand binding domain DUF3199 PF11436.8 RUS80643.1 - 9.8 6.2 6.8 28 4.8 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3199) BESS PF02944.20 RUS80644.1 - 4e-06 26.5 0.1 9.9e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 BESS motif MADF_DNA_bdg PF10545.9 RUS80644.1 - 0.00021 21.5 1.0 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like ORC6 PF05460.13 RUS80644.1 - 0.091 12.0 7.3 0.12 11.6 7.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CIAPIN1 PF05093.13 RUS80644.1 - 0.66 10.5 2.8 0.86 10.1 0.1 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TPR_1 PF00515.28 RUS80645.1 - 5.1e-08 32.4 9.1 0.026 14.3 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS80645.1 - 3.8e-07 29.7 11.1 0.027 14.6 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS80645.1 - 3e-05 23.9 4.4 1.3 9.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS80645.1 - 7.7e-05 22.5 3.9 0.66 10.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS80645.1 - 0.0059 16.3 5.1 0.38 10.5 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 RUS80645.1 - 0.0064 17.2 0.9 8.2 7.5 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS80645.1 - 0.021 15.0 2.7 8.9 6.6 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 USP8_dimer PF08969.11 RUS80645.1 - 0.022 14.9 1.4 0.41 10.8 0.1 2.8 2 1 1 3 3 3 0 USP8 dimerisation domain TPR_17 PF13431.6 RUS80645.1 - 0.023 15.0 1.3 0.25 11.8 0.0 3.3 4 1 1 5 5 3 0 Tetratricopeptide repeat DEK_C PF08766.11 RUS80645.1 - 0.03 14.3 0.1 0.99 9.4 0.1 2.6 1 1 1 2 2 2 0 DEK C terminal domain TPR_12 PF13424.6 RUS80645.1 - 0.034 14.4 4.1 14 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS80645.1 - 0.1 12.6 0.1 2.9 8.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS80645.1 - 0.13 12.9 0.3 0.13 12.9 0.3 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS80645.1 - 2.7 8.8 12.5 10 7.0 0.0 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80646.1 - 1.3e-05 25.4 3.6 3.6e-05 24.0 1.5 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS80646.1 - 0.0079 15.6 1.3 0.01 15.3 1.3 1.1 1 0 0 1 1 1 1 MalT-like TPR region Bmt2 PF11968.8 RUS80647.1 - 4.6e-10 39.7 0.0 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 RUS80647.1 - 1.1e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS80647.1 - 0.16 12.6 0.0 0.74 10.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF3572 PF12096.8 RUS80649.1 - 0.0099 16.1 0.5 0.019 15.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) SSP160 PF06933.11 RUS80649.1 - 1.5 6.9 17.7 0.42 8.7 11.1 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Cytochrom_C PF00034.21 RUS80649.1 - 2 9.6 7.3 0.35 12.0 2.2 2.3 1 1 1 2 2 2 0 Cytochrome c PRR18 PF15671.5 RUS80649.1 - 2.4 8.0 18.1 0.18 11.6 8.4 2.1 2 0 0 2 2 2 0 Proline-rich protein family 18 SelP_N PF04592.14 RUS80650.1 - 0.54 9.6 13.2 0.82 9.0 13.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Forkhead PF00250.18 RUS80651.1 - 2.7e-27 94.8 0.2 5.1e-27 94.0 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain DUF1199 PF06712.11 RUS80651.1 - 2.6 8.1 4.3 18 5.4 4.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1199) SNF PF00209.18 RUS80653.1 - 7.4e-153 510.0 21.8 2.1e-152 508.5 21.8 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family PMP22_Claudin PF00822.20 RUS80653.1 - 1.3 8.8 8.7 2.2 8.1 1.1 3.2 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin family FAR1 PF03101.15 RUS80654.1 - 0.048 14.4 0.0 0.21 12.3 0.0 2.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF4147 PF13660.6 RUS80655.1 - 2.9e-63 213.5 0.1 4.5e-63 212.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 RUS80655.1 - 7.3e-28 96.9 0.7 1.6e-27 95.9 0.7 1.6 1 0 0 1 1 1 1 MOFRL family DUF4147 PF13660.6 RUS80656.1 - 4.9e-75 252.0 3.2 5.5e-75 251.8 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 RUS80656.1 - 1.3e-33 115.4 6.1 5e-33 113.5 6.1 2.0 1 1 0 1 1 1 1 MOFRL family ARID PF01388.21 RUS80657.1 - 3.5e-16 59.6 0.1 8.7e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain VWD PF00094.25 RUS80658.1 - 1.8e-16 60.8 15.8 5.1e-11 43.1 2.3 4.1 4 0 0 4 4 4 2 von Willebrand factor type D domain EGF_Tenascin PF18720.1 RUS80658.1 - 3.4e-07 30.2 31.3 0.00095 19.2 11.6 3.5 2 0 0 2 2 2 2 Tenascin EGF domain EGF_2 PF07974.13 RUS80658.1 - 1.1e-05 25.7 40.6 0.00053 20.3 11.2 4.1 3 0 0 3 3 3 2 EGF-like domain DUF3326 PF11805.8 RUS80659.1 - 0.0033 16.3 11.8 0.71 8.7 2.0 3.5 1 1 3 4 4 4 3 Protein of unknown function (DUF3326) Polyoma_coat2 PF00761.20 RUS80659.1 - 4.1 7.0 10.4 2.8 7.6 9.0 1.4 1 1 0 1 1 1 0 Polyomavirus coat protein BPA_C PF18040.1 RUS80660.1 - 0.006 16.5 6.0 0.67 9.9 1.1 3.4 1 1 1 3 3 3 2 beta porphyranase A C-terminal DUF4292 PF14125.6 RUS80660.1 - 0.032 13.9 3.1 4.8 6.8 0.2 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4292) SspH PF08141.12 RUS80660.1 - 0.21 11.7 6.9 12 6.1 0.4 4.9 1 1 3 6 6 6 0 Small acid-soluble spore protein H family BppL_N PF18338.1 RUS80660.1 - 5 7.1 41.5 1.3 8.9 2.3 7.3 5 2 1 6 6 6 0 Lower baseplate protein N-terminal domain VWD PF00094.25 RUS80661.1 - 4.5e-24 85.5 12.6 3.9e-15 56.5 1.2 3.3 3 0 0 3 3 3 2 von Willebrand factor type D domain Laminin_G_3 PF13385.6 RUS80661.1 - 3e-05 24.2 1.6 0.11 12.6 0.0 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 RUS80661.1 - 0.0013 19.1 31.7 0.0021 18.4 8.7 5.9 5 1 0 5 5 5 2 EGF-like domain I-EGF_1 PF18372.1 RUS80661.1 - 0.79 9.9 21.4 0.055 13.6 3.6 3.2 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 RUS80661.1 - 1.7 8.8 41.5 0.073 13.1 11.1 5.3 4 0 0 4 4 4 0 Tenascin EGF domain hEGF PF12661.7 RUS80661.1 - 3.5 8.4 31.4 0.52 11.0 6.5 5.5 4 0 0 4 4 4 0 Human growth factor-like EGF VWD PF00094.25 RUS80662.1 - 1.8e-48 164.8 8.7 8.9e-13 48.8 0.1 5.2 4 0 0 4 4 4 4 von Willebrand factor type D domain PAN_1 PF00024.26 RUS80662.1 - 1.5e-21 76.1 16.3 1.1e-07 31.7 0.9 5.8 3 1 1 4 4 4 4 PAN domain TIG PF01833.24 RUS80663.1 - 0.019 15.0 3.2 0.035 14.2 2.4 2.0 1 1 0 1 1 1 0 IPT/TIG domain VWD PF00094.25 RUS80664.1 - 0.0017 18.7 0.9 0.0017 18.7 0.9 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain ApbA PF02558.16 RUS80665.1 - 0.19 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA APG9 PF04109.16 RUS80666.1 - 1.3e-165 552.1 18.6 1.5e-165 551.9 18.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Sas10_Utp3 PF04000.15 RUS80668.1 - 1.2e-13 51.5 0.5 3.5e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MukF_C PF17193.4 RUS80668.1 - 0.19 11.9 1.2 1 9.5 0.1 2.2 2 0 0 2 2 2 0 MukF C-terminal domain Spt5_N PF11942.8 RUS80668.1 - 0.8 10.7 9.2 1.9 9.5 9.2 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4503 PF14951.6 RUS80669.1 - 2.8e-18 65.6 10.3 3.4e-18 65.3 10.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF4503 PF14951.6 RUS80670.1 - 5.1e-07 28.5 0.1 1.5e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4503) HEAT PF02985.22 RUS80670.1 - 0.066 13.5 0.0 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 HEAT repeat DUF4502 PF14950.6 RUS80672.1 - 1.7e-10 40.9 1.5 1.9e-10 40.8 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) NPR1_interact PF15699.5 RUS80673.1 - 0.61 10.7 5.1 0.53 10.9 2.6 2.0 1 1 1 2 2 2 0 NPR1 interacting DUF3020 PF11223.8 RUS80673.1 - 0.62 10.6 6.8 0.17 12.4 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DUF1295 PF06966.12 RUS80674.1 - 2.4e-76 256.3 2.5 2.9e-76 256.1 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RUS80674.1 - 1e-08 35.3 0.3 1e-08 35.3 0.3 2.0 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 RUS80674.1 - 3.6e-05 24.1 0.1 3.6e-05 24.1 0.1 2.6 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 RUS80674.1 - 0.00098 19.5 0.0 0.00098 19.5 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ATP-synt_S1 PF05827.12 RUS80674.1 - 0.039 13.8 0.1 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) ORC6 PF05460.13 RUS80675.1 - 0.0014 18.0 3.7 0.074 12.3 0.2 2.5 2 1 1 3 3 3 2 Origin recognition complex subunit 6 (ORC6) MFAP1 PF06991.11 RUS80675.1 - 0.025 14.4 10.1 0.035 14.0 10.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TFIIB PF00382.19 RUS80675.1 - 0.041 13.9 0.1 31 4.7 0.0 3.3 2 1 1 3 3 3 0 Transcription factor TFIIB repeat PDZ PF00595.24 RUS80676.1 - 1.8e-56 188.4 7.0 4.8e-17 62.1 0.1 4.4 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 RUS80676.1 - 8.5e-33 111.9 50.8 5.4e-10 38.9 1.0 6.6 3 1 3 7 7 7 7 Leucine rich repeat PDZ_6 PF17820.1 RUS80676.1 - 7e-29 99.5 5.0 5.2e-09 35.8 0.1 4.5 4 0 0 4 4 4 3 PDZ domain LRR_4 PF12799.7 RUS80676.1 - 7.2e-22 77.1 62.0 8.3e-07 29.2 0.6 9.1 4 2 4 9 9 9 8 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 RUS80676.1 - 5.3e-16 58.7 7.1 0.00027 21.2 0.2 4.4 3 1 1 4 4 4 3 PDZ domain LRR_9 PF14580.6 RUS80676.1 - 0.0001 21.8 26.1 0.018 14.6 1.9 4.9 1 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 RUS80676.1 - 4.7 8.2 44.9 4.8 8.1 0.1 11.3 9 2 1 10 10 10 0 Leucine Rich Repeat IL17 PF06083.11 RUS80678.1 - 1.2e-08 35.3 1.0 2.2e-08 34.4 1.0 1.5 1 0 0 1 1 1 1 Interleukin-17 DUF971 PF06155.12 RUS80678.1 - 0.31 11.7 1.0 2.1 9.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF971) GREB1 PF15782.5 RUS80679.1 - 4.6 4.2 25.6 4.8 4.2 25.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CRAL_TRIO PF00650.20 RUS80680.1 - 5.2e-38 130.3 0.2 7.4e-38 129.8 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 RUS80680.1 - 2.8e-09 37.6 0.2 6e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.6 RUS80680.1 - 4.2e-08 33.5 0.1 7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RUS80680.1 - 2e-05 24.7 1.1 4.9e-05 23.4 1.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ras PF00071.22 RUS80681.1 - 2.3e-18 66.3 0.0 2.6e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS80681.1 - 8.8e-09 35.6 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glycos_transf_N PF04413.16 RUS80681.1 - 0.0015 18.2 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF1802 PF08819.11 RUS80681.1 - 0.056 13.3 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) Alpha_L_fucos PF01120.17 RUS80682.1 - 4.9e-86 289.3 16.2 5.8e-86 289.1 16.2 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 RUS80682.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Phage_Treg PF04761.12 RUS80682.1 - 0.03 14.4 0.2 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator Ribosomal_60s PF00428.19 RUS80683.1 - 2.3e-25 89.0 12.1 3e-25 88.6 12.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein PHD PF00628.29 RUS80687.1 - 4.7e-17 61.6 25.7 1.3e-09 37.8 13.2 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 RUS80687.1 - 8.5e-12 44.6 0.0 1.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 RUS80687.1 - 1.4e-05 24.5 6.5 0.068 12.7 2.8 3.0 2 0 0 2 2 2 2 PHD-finger FHA PF00498.26 RUS80687.1 - 0.0021 18.3 0.0 0.0091 16.3 0.0 2.1 1 0 0 1 1 1 1 FHA domain C1_1 PF00130.22 RUS80687.1 - 0.0025 17.7 1.8 0.0025 17.7 1.8 2.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Med21 PF11221.8 RUS80688.1 - 1.3e-29 103.4 3.6 3.6e-29 101.9 3.6 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.11 RUS80688.1 - 0.0074 15.4 2.6 0.0074 15.4 2.6 1.4 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) JLPA PF16668.5 RUS80688.1 - 0.035 13.2 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Adhesin from Campylobacter DUF871 PF05913.11 RUS80688.1 - 0.053 12.7 0.3 0.071 12.3 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) IL11 PF07400.11 RUS80688.1 - 0.068 12.8 0.3 0.22 11.1 0.3 1.9 2 0 0 2 2 2 0 Interleukin 11 Malectin PF11721.8 RUS80689.1 - 1.1e-40 139.4 0.1 1.5e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Malectin domain ATP_bind_1 PF03029.17 RUS80690.1 - 1.4e-89 300.1 0.5 1.5e-89 299.9 0.5 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 RUS80690.1 - 0.00065 20.3 0.0 0.0017 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 RUS80690.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 RUS80690.1 - 0.0011 18.8 0.0 0.0066 16.3 0.0 2.2 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop GTP_EFTU PF00009.27 RUS80690.1 - 0.0011 18.5 0.2 0.037 13.6 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.23 RUS80690.1 - 0.0012 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 RUS80690.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 RUS80690.1 - 0.0078 16.1 0.1 1.1 9.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RUS80690.1 - 0.008 16.5 0.0 0.025 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RUS80690.1 - 0.012 16.0 0.0 0.037 14.4 0.0 1.9 1 1 1 2 2 1 0 RNA helicase AAA_17 PF13207.6 RUS80690.1 - 0.019 15.4 0.1 0.072 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 RUS80690.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 RUS80690.1 - 0.031 14.2 0.1 9.8 6.1 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 RUS80690.1 - 0.042 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RUS80690.1 - 0.045 13.9 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RUS80690.1 - 0.055 13.8 0.1 0.99 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RUS80690.1 - 0.058 13.8 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 RUS80690.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS80690.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 RUS80690.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RUS80690.1 - 0.094 12.5 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.15 RUS80690.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_14 PF13173.6 RUS80690.1 - 0.11 12.5 0.0 0.51 10.4 0.0 2.0 2 1 0 3 3 2 0 AAA domain CobU PF02283.16 RUS80690.1 - 0.15 11.6 0.1 0.53 9.8 0.0 1.9 3 0 0 3 3 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cytidylate_kin PF02224.18 RUS80690.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 RUS80690.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1951 PF09188.10 RUS80690.1 - 0.45 10.5 3.6 1 9.4 0.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1951) zf-C4pol PF14260.6 RUS80691.1 - 0.032 14.7 4.1 0.032 14.7 4.1 3.0 2 2 2 4 4 4 0 C4-type zinc-finger of DNA polymerase delta ATG16 PF08614.11 RUS80691.1 - 0.14 12.3 46.2 0.42 10.8 22.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 RUS80691.1 - 0.18 10.7 45.1 0.055 12.4 15.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 RUS80691.1 - 0.19 11.0 43.6 0.032 13.6 12.7 3.1 1 1 2 3 3 3 0 FAM76 protein Lebercilin PF15619.6 RUS80691.1 - 0.59 9.8 48.9 0.31 10.7 16.7 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 RUS80691.1 - 0.64 10.4 41.8 2.3 8.6 19.2 2.4 1 1 2 3 3 3 0 Fez1 MAD PF05557.13 RUS80691.1 - 0.78 8.0 44.4 3.1 6.1 32.4 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.6 RUS80691.1 - 0.85 8.9 34.2 0.2 11.0 20.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MCC-bdg_PDZ PF10506.9 RUS80691.1 - 1.1 9.3 14.4 0.92 9.6 0.5 3.5 2 1 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PKcGMP_CC PF16808.5 RUS80691.1 - 1.5 8.7 20.2 0.73 9.7 0.1 5.4 3 2 2 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 RUS80691.1 - 1.8 7.9 44.2 7.4 5.9 20.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 AUDH_Cupin PF18637.1 RUS80691.1 - 3.2 7.8 5.6 1.3 9.0 2.7 1.9 1 1 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain V_ATPase_I PF01496.19 RUS80691.1 - 4.5 5.1 23.7 6.2 4.6 23.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.21 RUS80691.1 - 6.6 6.2 39.7 5.1 6.6 14.9 3.1 1 1 2 3 3 3 0 Intermediate filament protein AAA_13 PF13166.6 RUS80691.1 - 8.8 4.8 31.1 10 4.6 10.0 2.3 1 1 1 2 2 2 0 AAA domain TMEM154 PF15102.6 RUS80693.1 - 0.036 14.0 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family SWIB PF02201.18 RUS80693.1 - 0.042 13.7 0.4 0.094 12.6 0.1 1.6 2 0 0 2 2 2 0 SWIB/MDM2 domain Plectin PF00681.20 RUS80694.1 - 2.6e-194 628.9 45.1 0.0027 17.5 0.0 80.4 69 19 17 86 86 86 47 Plectin repeat Spectrin PF00435.21 RUS80694.1 - 1.1e-138 453.3 256.0 8.2e-11 42.3 4.9 33.7 31 4 4 35 35 35 25 Spectrin repeat CH PF00307.31 RUS80694.1 - 4.7e-22 78.2 0.1 3.3e-20 72.3 0.0 3.7 3 0 0 3 3 2 1 Calponin homology (CH) domain SH3_10 PF17902.1 RUS80694.1 - 5.4e-19 68.0 0.1 1.5e-18 66.6 0.1 1.9 1 0 0 1 1 1 1 SH3 domain DUF4585 PF15232.6 RUS80694.1 - 0.00011 22.2 0.5 11 6.1 0.0 7.4 8 0 0 8 8 8 1 Domain of unknown function (DUF4585) OCRE PF17780.1 RUS80694.1 - 0.00027 20.9 4.8 1.5e+02 2.5 0.0 11.1 14 0 0 14 14 14 0 OCRE domain CAMSAP_CH PF11971.8 RUS80694.1 - 0.00034 20.4 0.0 0.0017 18.2 0.0 2.3 1 0 0 1 1 1 1 CAMSAP CH domain Phage_holin_7_1 PF16081.5 RUS80694.1 - 0.24 11.6 4.1 0.21 11.7 0.5 3.0 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family AAA_lid_9 PF17871.1 RUS80694.1 - 0.25 11.3 5.7 0.71 9.8 0.9 4.8 2 0 0 2 2 2 0 AAA lid domain GPS2_interact PF15784.5 RUS80694.1 - 4.1 7.9 13.5 0.094 13.2 0.0 5.7 5 0 0 5 5 4 0 G-protein pathway suppressor 2-interacting domain Gluconate_2-dh3 PF13618.6 RUS80694.1 - 4.5 7.5 8.4 15 5.8 0.3 4.8 4 0 0 4 4 4 0 Gluconate 2-dehydrogenase subunit 3 Peptidase_M13_N PF05649.13 RUS80695.1 - 6.2e-55 187.4 0.5 7.6e-55 187.1 0.5 1.0 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS80696.1 - 6.4e-57 192.5 0.0 7.1e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Arf PF00025.21 RUS80697.1 - 3.4e-52 176.4 0.0 4.6e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS80697.1 - 1.7e-13 50.4 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 RUS80697.1 - 2.1e-12 46.9 0.0 3.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS80697.1 - 5.6e-12 45.9 0.0 9.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RUS80697.1 - 2.9e-08 33.4 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS80697.1 - 0.00058 19.9 0.0 0.0053 16.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF765 PF05570.11 RUS80697.1 - 0.17 12.1 0.3 0.31 11.3 0.3 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) SNF PF00209.18 RUS80698.1 - 2e-178 594.3 32.2 2.3e-178 594.1 32.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Lipocalin_7 PF14651.6 RUS80700.1 - 2e-05 24.5 0.1 2.4e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Ctr PF04145.15 RUS80702.1 - 2.6e-12 47.6 1.1 2.6e-12 47.6 1.1 1.9 2 1 0 2 2 2 1 Ctr copper transporter family 7tm_2 PF00002.24 RUS80703.1 - 5.1e-21 75.1 14.1 1.1e-20 74.0 14.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) C5-epim_C PF06662.13 RUS80704.1 - 2e-68 229.6 0.0 3.2e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Pec_lyase PF09492.10 RUS80704.1 - 0.022 14.1 0.0 0.38 10.0 0.0 2.2 2 0 0 2 2 2 0 Pectic acid lyase DUF4962 PF16332.5 RUS80704.1 - 0.086 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) CD225 PF04505.12 RUS80706.1 - 7.6e-16 58.0 1.5 1.5e-15 57.0 0.3 1.8 1 1 1 2 2 2 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 RUS80706.1 - 0.022 14.5 6.2 0.096 12.5 5.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) DUF2231 PF09990.9 RUS80706.1 - 0.039 14.4 0.5 0.065 13.7 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF829 PF05705.14 RUS80707.1 - 1.3e-40 139.8 0.0 1.7e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 RUS80707.1 - 0.14 11.6 0.0 17 4.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Arf PF00025.21 RUS80708.1 - 3.1e-63 212.4 0.0 3.6e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS80708.1 - 1e-14 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS80708.1 - 2.1e-14 53.4 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS80708.1 - 6.2e-11 42.0 0.0 7.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS80708.1 - 4.9e-09 35.8 0.3 1.2e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS80708.1 - 8.3e-08 31.9 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS80708.1 - 0.0019 18.3 0.0 0.0066 16.5 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RUS80708.1 - 0.047 13.0 0.1 0.071 12.4 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.12 RUS80708.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF2754 PF10953.8 RUS80708.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF2431 PF10354.9 RUS80710.1 - 8.7e-38 130.2 0.0 1.4e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 RUS80710.1 - 1e-06 29.1 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Bromodomain PF00439.25 RUS80711.1 - 1.7e-20 72.9 0.0 4e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 RUS80711.1 - 4.7e-13 49.1 21.9 3e-09 36.9 9.2 4.5 4 1 0 4 4 4 2 B-box zinc finger PHD PF00628.29 RUS80711.1 - 1.1e-05 25.2 13.0 1.1e-05 25.2 13.0 4.8 3 2 1 4 4 4 1 PHD-finger zf-RING_5 PF14634.6 RUS80711.1 - 0.00027 20.8 3.1 0.00027 20.8 3.1 5.3 5 0 0 5 5 5 1 zinc-RING finger domain DUF3418 PF11898.8 RUS80711.1 - 0.032 12.9 1.8 0.052 12.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Apolipoprotein PF01442.18 RUS80711.1 - 0.051 13.4 2.3 0.14 12.0 1.4 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Siva PF05458.12 RUS80711.1 - 3.2 7.4 17.4 0.52 10.0 1.3 3.5 3 0 0 3 3 3 0 Cd27 binding protein (Siva) 7tm_1 PF00001.21 RUS80713.1 - 8.2e-22 77.8 16.1 2.3e-21 76.3 16.1 1.8 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS80713.1 - 0.03 14.1 8.7 1 9.1 8.7 2.4 1 1 0 1 1 1 0 Olfactory receptor 7TM_GPCR_Srv PF10323.9 RUS80713.1 - 0.61 9.4 10.5 1.4 8.2 10.5 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF3299 PF11736.8 RUS80713.1 - 0.76 9.8 4.0 0.38 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) DUF948 PF06103.11 RUS80715.1 - 0.028 14.7 0.1 0.14 12.4 0.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phasin_2 PF09361.10 RUS80715.1 - 7.4 6.9 9.7 0.41 10.9 1.2 2.7 3 0 0 3 3 3 0 Phasin protein PEP-utilisers_N PF05524.13 RUS80718.1 - 0.018 15.2 0.3 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1397 PF07165.11 RUS80719.1 - 0.0092 15.4 0.2 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) DUF19 PF01579.18 RUS80719.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF19 PF01579.18 RUS80720.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF19) 7tm_2 PF00002.24 RUS80722.1 - 1.7e-56 191.3 18.7 2.3e-56 190.8 18.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS80722.1 - 5.9e-13 48.9 2.0 1.2e-12 47.9 2.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain 7tm_1 PF00001.21 RUS80723.1 - 5.5e-16 58.7 5.9 8.7e-16 58.0 5.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CDK5_activator PF03261.15 RUS80724.1 - 2.3e-103 346.6 14.0 2.5e-96 323.4 3.3 2.0 1 1 1 2 2 2 2 Cyclin-dependent kinase 5 activator protein 7tm_1 PF00001.21 RUS80725.1 - 2.8e-84 282.5 5.0 3.5e-84 282.2 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS80725.1 - 2.5e-10 40.2 13.0 1.9e-06 27.4 7.5 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS80725.1 - 1.5e-07 31.5 9.5 9.1e-07 28.9 4.6 2.3 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS80725.1 - 1.4e-06 28.2 9.8 1.4e-06 28.2 9.8 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx YqgB PF11036.8 RUS80725.1 - 0.057 13.1 0.5 0.43 10.3 0.0 2.6 3 0 0 3 3 3 0 Virulence promoting factor Pkinase PF00069.25 RUS80726.1 - 2.8e-66 223.6 0.0 7.1e-66 222.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80726.1 - 6.4e-35 120.7 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 RUS80726.1 - 8.9e-21 74.4 4.5 1.8e-20 73.4 4.5 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 RUS80726.1 - 2.8e-05 23.1 0.0 5.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS80726.1 - 4.1e-05 23.1 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 RUS80726.1 - 0.045 13.4 0.6 2.8 7.5 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RUS80726.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family JTB PF05439.12 RUS80727.1 - 1.1e-22 80.1 1.4 1.1e-22 80.1 1.4 1.4 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) MTHFR_C PF12225.8 RUS80727.1 - 0.001 18.6 1.0 0.0016 18.0 1.0 1.4 1 0 0 1 1 1 1 Methylene-tetrahydrofolate reductase C terminal SDH_sah PF01972.16 RUS80727.1 - 0.046 12.7 0.1 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase N6-adenineMlase PF10237.9 RUS80728.1 - 6e-20 71.7 0.0 9.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-GRF PF06839.12 RUS80728.1 - 0.00091 19.3 0.2 0.00091 19.3 0.2 2.1 2 0 0 2 2 2 1 GRF zinc finger DHHC PF01529.20 RUS80728.1 - 0.26 11.4 3.5 0.6 10.2 3.5 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE PF01363.21 RUS80728.1 - 1.7 8.9 12.1 2.2 8.5 4.3 2.5 2 0 0 2 2 2 0 FYVE zinc finger Homeodomain PF00046.29 RUS80730.1 - 7.6e-21 73.7 4.5 1.3e-20 73.0 4.5 1.4 1 0 0 1 1 1 1 Homeodomain DNA_pol_phi PF04931.13 RUS80731.1 - 0.084 11.0 24.2 0.14 10.3 24.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RUS80731.1 - 2.5 7.3 29.0 3.3 6.9 29.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RUS80731.1 - 3.7 6.6 32.1 5 6.2 32.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 RUS80731.1 - 5.7 6.2 10.1 7.8 5.8 10.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 RUS80731.1 - 6.6 4.9 14.5 8.7 4.5 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.6 RUS80732.1 - 2.3 9.3 10.2 0.51 11.4 6.8 1.6 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF4644 PF15486.6 RUS80732.1 - 5.3 6.8 13.5 17 5.2 13.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) MPS-4 PF17523.2 RUS80733.1 - 0.14 12.3 3.3 0.42 10.8 3.3 1.8 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 SR-25 PF10500.9 RUS80734.1 - 0.02 14.5 8.3 0.022 14.4 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C3HC4_3 PF13920.6 RUS80735.1 - 9.1e-05 22.2 10.9 9.1e-05 22.2 10.9 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-NF-X1 PF01422.17 RUS80736.1 - 2.4e-10 40.3 107.9 6.2e-06 26.2 15.0 17.7 18 0 0 18 18 18 10 NF-X1 type zinc finger VIR_N PF15912.5 RUS80736.1 - 2.2 7.8 8.5 0.26 10.9 1.5 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal PRP1_N PF06424.12 RUS80736.1 - 2.4 8.6 11.8 1.3 9.4 5.6 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Fip1 PF05182.13 RUS80738.1 - 3e-22 77.9 1.2 5.5e-22 77.0 1.2 1.5 1 0 0 1 1 1 1 Fip1 motif ANAPC4_WD40 PF12894.7 RUS80739.1 - 4.9e-08 33.1 0.0 6.5e-05 23.2 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS80739.1 - 6.5e-08 33.1 0.3 0.21 12.5 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat SOCS_box PF07525.16 RUS80739.1 - 0.00078 19.8 1.3 0.0019 18.5 1.3 1.7 1 0 0 1 1 1 1 SOCS box Ge1_WD40 PF16529.5 RUS80739.1 - 0.051 12.5 0.0 9.5 5.1 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LRR_6 PF13516.6 RUS80740.1 - 6.3e-18 63.3 22.3 0.00038 20.3 0.0 8.6 8 1 1 9 9 9 5 Leucine Rich repeat EF-hand_7 PF13499.6 RUS80740.1 - 7.4e-10 39.1 0.5 2e-09 37.7 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS80740.1 - 1.9e-05 23.9 2.1 0.013 15.0 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS80740.1 - 6.4e-05 22.6 2.3 0.3 11.1 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RUS80740.1 - 7.2e-05 22.1 1.8 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 EF hand LRR_1 PF00560.33 RUS80740.1 - 0.00038 20.6 4.7 70 4.6 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich Repeat EF-hand_8 PF13833.6 RUS80740.1 - 0.0006 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Mob_synth_C PF06463.13 RUS80740.1 - 0.14 12.0 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C GH3 PF03321.13 RUS80741.1 - 3.7e-137 458.4 0.0 4.3e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter adh_short PF00106.25 RUS80743.1 - 1.5e-47 161.6 0.4 1.9e-47 161.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS80743.1 - 1.2e-42 146.1 0.1 1.5e-42 145.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS80743.1 - 2.2e-10 40.7 1.6 5.7e-10 39.4 1.6 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 RUS80743.1 - 0.0039 16.2 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS80743.1 - 0.0046 16.4 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cast PF10174.9 RUS80744.1 - 4.9e-119 398.7 159.3 3.9e-116 389.2 159.3 3.0 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HMMR_N PF15905.5 RUS80744.1 - 0.0023 17.5 16.5 0.0023 17.5 16.5 6.7 1 1 7 8 8 8 4 Hyaluronan mediated motility receptor N-terminal zf-CCHC_2 PF13696.6 RUS80745.1 - 0.00063 19.5 3.9 0.0012 18.6 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RUS80745.1 - 0.001 19.0 2.8 0.0021 18.0 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS80745.1 - 0.0089 16.0 4.8 0.022 14.7 4.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS80745.1 - 0.76 9.5 5.3 1.6 8.5 5.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger UAA PF08449.11 RUS80746.1 - 1.3e-100 336.5 22.2 1.5e-100 336.4 22.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RUS80746.1 - 4.2e-06 27.0 34.1 1.8e-05 24.9 14.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 RUS80746.1 - 6.8e-05 22.3 15.4 0.0029 17.0 2.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RUS80746.1 - 0.00055 19.2 3.8 0.00055 19.2 3.8 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter SLATT_6 PF18169.1 RUS80746.1 - 0.026 14.1 0.7 0.084 12.5 0.7 1.9 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 PUNUT PF16913.5 RUS80746.1 - 0.12 11.6 22.7 0.025 13.8 7.6 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport rve PF00665.26 RUS80747.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 RUS80747.1 - 0.022 14.9 0.1 0.072 13.2 0.0 1.9 1 1 1 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Lectin_C PF00059.21 RUS80748.1 - 1e-12 48.7 0.1 2e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain SET PF00856.28 RUS80751.1 - 1.2e-23 84.3 0.3 6.6e-23 81.9 0.3 2.1 1 1 0 1 1 1 1 SET domain FYRC PF05965.14 RUS80751.1 - 9.6e-18 64.1 0.0 1.9e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 RUS80752.1 - 2.6e-14 52.8 0.1 5.9e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 RUS80752.1 - 2.1e-12 47.1 9.2 2.1e-12 47.1 9.2 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RUS80752.1 - 1.7e-10 41.1 9.6 1.7e-10 41.1 9.6 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 RUS80754.1 - 0.005 16.7 1.2 0.005 16.7 1.2 3.2 2 1 1 3 3 3 3 PHD-finger zf-CXXC PF02008.20 RUS80755.1 - 1.4e-08 34.6 13.7 1.4e-08 34.6 13.7 3.2 3 1 0 3 3 3 1 CXXC zinc finger domain Ribosomal_L34e PF01199.18 RUS80755.1 - 1.3 9.4 7.9 0.5 10.7 3.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L34e Pkinase PF00069.25 RUS80756.1 - 8.1e-68 228.6 0.0 9.6e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80756.1 - 2.4e-26 92.6 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80756.1 - 5.5e-08 32.5 0.0 1.7e-05 24.3 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 RUS80756.1 - 0.001 19.0 0.0 0.0067 16.4 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS80756.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS80756.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 RUS80756.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC1 family DUF4488 PF14869.6 RUS80756.1 - 0.17 11.8 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Pkinase PF00069.25 RUS80757.1 - 1.8e-43 148.8 0.0 2.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80757.1 - 3e-14 52.9 0.0 3.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80757.1 - 2.1e-06 27.3 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS80757.1 - 0.0012 18.9 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS80757.1 - 0.02 14.2 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS80757.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 RUS80757.1 - 0.061 12.4 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Y_phosphatase PF00102.27 RUS80758.1 - 0.0018 17.9 0.1 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase MIase PF02426.16 RUS80758.1 - 0.095 12.9 0.1 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Muconolactone delta-isomerase Y_phosphatase PF00102.27 RUS80759.1 - 1.4e-55 188.4 0.1 2e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS80759.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Tcp10_C PF07202.13 RUS80760.1 - 7.7e-06 26.0 1.4 0.03 14.3 0.1 2.3 1 1 1 2 2 2 2 T-complex protein 10 C-terminus DUF4968 PF16338.5 RUS80760.1 - 8.4e-05 22.8 4.1 1.1 9.6 0.2 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF4968) CheF-arch PF04283.12 RUS80760.1 - 0.021 14.6 7.8 12 5.6 0.1 4.1 1 1 1 2 2 2 0 Chemotaxis signal transduction system protein F from archaea VWD PF00094.25 RUS80760.1 - 0.1 12.8 6.1 5.5 7.2 0.4 2.6 1 1 1 2 2 2 0 von Willebrand factor type D domain SspB PF04386.13 RUS80760.1 - 0.6 10.0 4.2 1.5 8.7 4.2 1.7 1 0 0 1 1 1 0 Stringent starvation protein B Nop14 PF04147.12 RUS80760.1 - 1.4 7.0 40.1 1.7 6.7 40.1 1.1 1 0 0 1 1 1 0 Nop14-like family Interfer-bind PF09294.10 RUS80760.1 - 2.1 8.7 7.0 43 4.5 1.1 3.2 1 1 2 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III INPP5B_PH PF16776.5 RUS80760.1 - 4.9 6.9 7.4 47 3.7 2.9 3.2 1 1 3 4 4 4 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain CobT PF06213.12 RUS80760.1 - 8.7 5.6 29.7 13 5.0 29.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vps26 PF03643.15 RUS80762.1 - 5.3e-56 189.6 1.2 6.9e-56 189.3 1.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 RUS80762.1 - 8.7e-08 32.3 0.0 2.6e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RNase_H PF00075.24 RUS80763.1 - 4.3e-07 30.2 1.6 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS80763.1 - 0.054 13.3 0.3 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase-like MRP-L27 PF09809.9 RUS80764.1 - 2.9e-25 88.3 0.0 4.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Adeno_52K PF03052.15 RUS80764.1 - 0.048 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Ldl_recept_a PF00057.18 RUS80765.1 - 9.4e-25 86.5 37.3 1.6e-08 34.6 7.4 3.2 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A PT PF04886.12 RUS80765.1 - 0.016 14.8 54.9 3.1e+02 1.0 10.7 4.8 1 1 1 2 2 2 0 PT repeat STAT2_C PF12188.8 RUS80766.1 - 6.4 6.8 17.6 1.5 8.8 0.3 5.3 5 1 0 6 6 6 0 Signal transducer and activator of transcription 2 C terminal TMEM154 PF15102.6 RUS80767.1 - 0.0094 15.9 0.9 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family C2-set_2 PF08205.12 RUS80767.1 - 0.011 15.8 5.2 0.26 11.4 0.1 3.5 3 1 1 4 4 4 0 CD80-like C2-set immunoglobulin domain Syndecan PF01034.20 RUS80767.1 - 0.042 13.8 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain ASFV_J13L PF05568.11 RUS80767.1 - 0.54 10.0 4.8 0.19 11.4 0.7 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein rve PF00665.26 RUS80768.1 - 1.6e-11 44.4 0.0 3.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PHTB1_C PF14728.6 RUS80769.1 - 0.099 11.7 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus ATP-synt_F6 PF05511.11 RUS80770.1 - 3.6e-28 97.8 0.0 5.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 PIH1_CS PF18201.1 RUS80772.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 RUS80772.1 - 2.4e-05 23.8 0.1 0.00011 21.7 0.1 2.0 1 1 0 1 1 1 1 PIH1 N-terminal domain ArsA_HSP20 PF17886.1 RUS80772.1 - 0.00067 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA gag-asp_proteas PF13975.6 RUS80773.1 - 3.1e-06 27.7 0.0 6.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS80773.1 - 1.8e-05 25.3 0.0 3.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Paf1 PF03985.13 RUS80773.1 - 0.007 15.4 25.5 0.01 14.9 25.5 1.2 1 0 0 1 1 1 1 Paf1 CDC45 PF02724.14 RUS80773.1 - 0.015 13.6 31.8 0.019 13.3 31.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS80773.1 - 0.057 13.2 29.2 0.08 12.8 29.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVP_2 PF08284.11 RUS80773.1 - 0.15 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2052 PF09747.9 RUS80773.1 - 0.27 11.3 25.2 0.39 10.8 25.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 RUS80773.1 - 0.3 11.5 16.8 0.55 10.7 16.8 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 RUS80773.1 - 0.32 11.3 29.1 0.52 10.6 29.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LicD PF04991.13 RUS80773.1 - 0.35 11.0 11.9 7.9 6.5 12.5 2.1 2 0 0 2 2 2 0 LicD family ALMT PF11744.8 RUS80773.1 - 0.41 9.4 15.3 0.19 10.5 13.2 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter MCD PF05292.11 RUS80773.1 - 0.61 9.6 9.6 0.96 9.0 7.7 1.9 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain PTPRCAP PF15713.5 RUS80773.1 - 0.76 10.1 22.8 1.2 9.4 22.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Tim54 PF11711.8 RUS80773.1 - 2.5 6.8 23.9 4 6.1 23.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.6 RUS80773.1 - 2.7 7.7 20.2 4.5 7.0 20.2 1.3 1 0 0 1 1 1 0 AAA domain CDC27 PF09507.10 RUS80773.1 - 3.9 6.7 37.9 6.4 6.1 37.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.17 RUS80773.1 - 4.8 7.3 12.0 8.8 6.4 12.0 1.4 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 RUS80773.1 - 6 6.2 21.3 8.8 5.6 21.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 RUS80773.1 - 9.4 5.6 21.4 16 4.9 21.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIID-18kDa PF02269.16 RUS80774.1 - 0.013 15.6 0.1 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit PAN_1 PF00024.26 RUS80775.1 - 0.0098 15.8 0.2 0.014 15.4 0.2 1.2 1 0 0 1 1 1 1 PAN domain DUF1700 PF08006.11 RUS80776.1 - 0.41 10.2 12.2 0.44 10.1 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF1129 PF06570.11 RUS80776.1 - 2.6 7.5 5.3 3.2 7.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PAN_1 PF00024.26 RUS80777.1 - 4e-05 23.5 5.7 0.083 12.9 0.2 2.8 2 1 1 3 3 3 2 PAN domain Exonuc_VII_S PF02609.16 RUS80777.1 - 7.6e-05 22.7 11.2 0.086 12.9 3.7 3.1 1 1 1 2 2 2 2 Exonuclease VII small subunit Spc7 PF08317.11 RUS80777.1 - 0.015 14.2 0.3 0.022 13.6 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PAN_3 PF08277.12 RUS80777.1 - 0.037 13.8 2.5 4.5 7.1 0.2 2.3 2 0 0 2 2 2 0 PAN-like domain RGM_N PF06535.12 RUS80777.1 - 0.075 13.2 1.3 6.3 7.0 1.3 2.2 1 1 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus PAN_4 PF14295.6 RUS80777.1 - 0.23 11.4 2.8 9.1 6.3 0.1 2.7 3 0 0 3 3 3 0 PAN domain CBM_14 PF01607.24 RUS80778.1 - 1.5e-06 28.3 2.9 2.2e-06 27.8 2.9 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain PPC PF04151.15 RUS80780.1 - 3.8 8.7 9.8 8.2 7.6 9.8 1.6 1 1 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain ASH PF15780.5 RUS80782.1 - 1e-09 38.4 0.1 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4404 PF14357.6 RUS80783.1 - 0.011 16.3 0.4 0.011 16.3 0.4 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4404) NIT PF08376.10 RUS80784.1 - 4.4e-16 60.1 0.0 5.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Nitrate and nitrite sensing Guanylate_cyc PF00211.20 RUS80785.1 - 8.1e-29 100.5 0.3 1.7e-14 53.9 0.7 2.2 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF2769 PF10967.8 RUS80785.1 - 0.21 12.3 3.4 3.2 8.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2769) DUF5473 PF17567.2 RUS80786.1 - 4.5 7.6 8.6 0.084 13.2 0.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5473) DUF745 PF05335.13 RUS80787.1 - 0.001 18.8 19.0 0.001 18.8 19.0 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF745) IFT57 PF10498.9 RUS80787.1 - 0.0033 16.5 20.0 0.0033 16.5 20.0 4.0 1 1 3 4 4 4 1 Intra-flagellar transport protein 57 CLZ PF16526.5 RUS80787.1 - 0.011 16.1 3.6 0.011 16.1 3.6 7.6 3 2 5 8 8 8 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-ribbon_3 PF13248.6 RUS80787.1 - 0.072 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Fib_alpha PF08702.10 RUS80787.1 - 0.27 11.4 63.4 0.045 13.9 6.0 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family SCO1-SenC PF02630.14 RUS80787.1 - 0.45 10.4 2.5 1.9 8.4 0.4 2.9 1 1 2 3 3 3 0 SCO1/SenC DUF3584 PF12128.8 RUS80787.1 - 7.5 3.9 85.8 3.9 4.9 64.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) fn3 PF00041.21 RUS80788.1 - 4.3e-08 33.4 0.0 0.0016 18.7 0.0 3.3 2 1 0 2 2 2 2 Fibronectin type III domain zf-RING_UBOX PF13445.6 RUS80788.1 - 1.9e-06 27.8 6.6 1.9e-06 27.8 6.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS80788.1 - 3.3e-06 26.9 9.9 3.3e-06 26.9 9.9 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS80788.1 - 0.00015 21.5 9.2 0.00015 21.5 9.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS80788.1 - 0.0019 18.3 9.8 0.0019 18.3 9.8 2.8 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS80788.1 - 0.0079 16.0 10.3 0.0079 16.0 10.3 2.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 RXT2_N PF08595.11 RUS80788.1 - 0.043 13.8 1.9 0.089 12.8 1.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 RUS80788.1 - 0.12 12.7 15.8 0.37 11.2 15.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AIP3 PF03915.13 RUS80788.1 - 0.18 10.8 0.8 0.35 9.9 0.8 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 AraC_N PF06719.13 RUS80788.1 - 0.19 11.3 0.7 25 4.5 0.2 2.8 2 1 1 3 3 3 0 AraC-type transcriptional regulator N-terminus DUF4050 PF13259.6 RUS80788.1 - 0.34 11.2 1.5 0.89 9.8 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) zf-Nse PF11789.8 RUS80788.1 - 0.67 9.8 7.1 1.9 8.4 7.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DNA_pol_phi PF04931.13 RUS80788.1 - 0.78 7.8 8.7 1.3 7.0 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 RUS80788.1 - 0.97 9.9 12.5 2.4 8.6 12.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RUS80788.1 - 2.8 7.2 18.5 0.37 10.1 13.7 1.9 2 0 0 2 2 2 0 NOA36 protein MFS_1 PF07690.16 RUS80789.1 - 8.7e-07 28.2 0.1 8.7e-07 28.2 0.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS80790.1 - 2.1e-05 23.7 6.2 2.8e-05 23.2 6.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Musclin PF11037.8 RUS80790.1 - 0.074 13.0 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Glyco_hydro_9 PF00759.19 RUS80791.1 - 3.6e-94 316.5 8.8 3.9e-76 257.1 0.2 4.0 2 2 0 2 2 2 2 Glycosyl hydrolase family 9 Hormone_recep PF00104.30 RUS80793.1 - 6.8e-16 58.5 0.0 2e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Rhomboid PF01694.22 RUS80794.1 - 0.016 15.2 6.6 0.016 15.2 6.6 1.5 1 1 0 1 1 1 0 Rhomboid family BOFC_N PF08977.10 RUS80795.1 - 5e-19 68.0 0.0 2.6 8.1 0.0 8.9 1 1 8 9 9 9 7 Bypass of Forespore C, N terminal DUF5133 PF17196.4 RUS80795.1 - 9e-19 67.4 25.5 0.3 11.3 0.2 9.1 1 1 8 9 9 9 9 Protein of unknown function (DUF5133) DUF4390 PF14334.6 RUS80795.1 - 7.6e-08 31.9 8.3 0.99 8.8 0.1 4.6 1 1 4 6 6 6 6 Domain of unknown function (DUF4390) PTN_MK_C PF01091.18 RUS80795.1 - 3.1e-07 30.7 50.1 1.5 9.3 0.7 9.1 9 0 0 9 9 9 8 PTN/MK heparin-binding protein family, C-terminal domain Swi3 PF07962.12 RUS80795.1 - 0.014 15.4 11.0 69 3.5 0.1 6.8 1 1 3 4 4 4 0 Replication Fork Protection Component Swi3 VOMI PF03762.17 RUS80795.1 - 0.18 11.9 7.7 36 4.4 0.6 3.9 1 1 3 5 5 5 0 Vitelline membrane outer layer protein I (VOMI) Sec7_N PF12783.7 RUS80797.1 - 1.3e-21 77.2 0.5 2.8e-21 76.1 0.5 1.6 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal GDP_Man_Dehyd PF16363.5 RUS80798.1 - 1.2e-55 189.3 0.0 1.4e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS80798.1 - 3.5e-49 167.4 0.0 4.3e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS80798.1 - 2.4e-21 76.0 0.2 5.5e-21 74.8 0.2 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 RUS80798.1 - 7.3e-15 54.9 0.0 1.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 RUS80798.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RUS80798.1 - 1e-08 35.0 0.0 1.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.17 RUS80798.1 - 2.6e-08 33.3 0.0 4.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 RUS80798.1 - 6.2e-08 32.3 0.0 2.5e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 RUS80798.1 - 7.6e-06 25.9 0.2 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 RUS80798.1 - 1.2e-05 24.7 0.1 0.00021 20.5 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein UDPG_MGDP_dh_N PF03721.14 RUS80798.1 - 0.051 13.1 0.6 0.093 12.3 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 RUS80798.1 - 0.076 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 RUS80798.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rad60-SLD PF11976.8 RUS80800.1 - 0.0018 18.1 0.4 0.0083 15.9 0.2 2.0 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RUS80800.1 - 0.011 15.4 0.4 0.077 12.8 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin family EF-hand_1 PF00036.32 RUS80802.1 - 6.1e-18 63.0 2.9 4.5e-06 25.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RUS80802.1 - 2.3e-17 61.3 1.5 9.8e-05 22.0 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 RUS80802.1 - 1.5e-15 57.4 5.6 1.3e-09 38.4 2.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 RUS80802.1 - 6.5e-13 48.3 5.7 4.8e-09 35.9 0.6 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS80802.1 - 9.5e-09 34.4 8.3 0.005 16.3 0.2 4.5 4 0 0 4 4 4 3 EF hand ATPgrasp_N PF18130.1 RUS80802.1 - 0.0021 18.6 0.0 0.67 10.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp N-terminal domain EF-hand_9 PF14658.6 RUS80802.1 - 0.024 14.9 0.6 0.98 9.8 0.0 3.1 2 2 1 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 RUS80802.1 - 0.034 14.0 0.1 0.46 10.4 0.1 2.3 1 1 1 2 2 2 0 EF hand DnaJ PF00226.31 RUS80803.1 - 2.1e-22 79.0 0.4 4.7e-22 77.9 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain CLP_protease PF00574.23 RUS80804.1 - 3.8e-79 264.8 0.0 4.7e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease Thioredoxin_16 PF18569.1 RUS80804.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_transf_20 PF00982.21 RUS80804.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Pro_isomerase PF00160.21 RUS80805.1 - 4.3e-43 147.3 0.0 1.4e-42 145.7 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2C_adapt PF08793.10 RUS80805.1 - 0.06 13.5 0.1 0.3 11.3 0.4 2.0 2 0 0 2 2 2 0 2-cysteine adaptor domain Cohesin_HEAT PF12765.7 RUS80806.1 - 0.0021 18.3 0.5 73 3.8 0.1 5.1 4 1 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Pectinesterase PF01095.19 RUS80806.1 - 0.01 14.6 0.8 0.055 12.2 0.1 2.0 1 1 1 2 2 2 0 Pectinesterase PAS_6 PF08348.11 RUS80806.1 - 0.037 13.9 1.8 3.2 7.7 0.1 3.0 1 1 2 3 3 3 0 YheO-like PAS domain GatB_Yqey PF02637.18 RUS80806.1 - 0.18 11.7 0.0 79 3.1 0.0 3.1 1 1 4 5 5 5 0 GatB domain Ldt_C PF17969.1 RUS80806.1 - 0.18 12.5 2.0 38 5.1 0.0 4.5 1 1 6 7 7 7 0 L,D-transpeptidase C-terminal domain LPD23 PF18838.1 RUS80806.1 - 0.26 11.0 3.8 1.3e+02 2.5 0.1 4.5 1 1 4 6 6 6 0 Large polyvalent protein associated domain 23 Haemadin PF09065.10 RUS80806.1 - 2.6 7.9 16.2 2.9e+02 1.4 0.0 8.2 9 0 0 9 9 9 0 Haemadin PLA2G12 PF06951.11 RUS80807.1 - 0.0068 16.3 21.9 7.9 6.3 1.9 6.7 1 1 3 4 4 4 3 Group XII secretory phospholipase A2 precursor (PLA2G12) MTCP1 PF08991.10 RUS80807.1 - 0.064 13.5 33.7 0.64 10.3 1.7 5.8 1 1 5 6 6 6 0 Mature-T-Cell Proliferation I type PcF PF09461.10 RUS80807.1 - 0.8 10.1 36.7 1.8 9.0 1.8 4.8 1 1 3 4 4 4 0 Phytotoxin PcF protein Peptidase_U57 PF05582.12 RUS80807.1 - 1.8 7.7 3.5 55 2.9 0.0 3.6 1 1 3 5 5 5 0 YabG peptidase U57 Nucleoporin_FG2 PF15967.5 RUS80807.1 - 2 6.9 8.3 2.2 6.7 8.3 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region Pox_A11 PF05061.13 RUS80809.1 - 0.025 13.8 0.1 0.035 13.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF5347 PF17282.2 RUS80809.1 - 0.03 14.6 0.4 0.043 14.1 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5347) ISK_Channel PF02060.15 RUS80809.1 - 0.064 13.0 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Baculo_11_kDa PF06143.11 RUS80809.1 - 0.16 11.6 0.9 0.3 10.7 0.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Metallophos PF00149.28 RUS80810.1 - 5.1e-12 46.7 0.2 6.1e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 RUS80811.1 - 2.6e-15 57.5 1.2 3.7e-15 57.0 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CrgA PF06781.12 RUS80811.1 - 0.046 13.8 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 Cell division protein CrgA Pkinase_Tyr PF07714.17 RUS80812.1 - 5.6e-13 48.8 0.0 9.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS80812.1 - 3.1e-11 43.1 0.0 6.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain OSR1_C PF12202.8 RUS80812.1 - 0.083 13.1 0.1 0.2 11.9 0.1 1.7 1 1 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain HEAT_2 PF13646.6 RUS80813.1 - 5.3e-16 58.8 2.8 6.2e-08 32.9 2.3 2.9 2 1 1 3 3 3 2 HEAT repeats TIR_2 PF13676.6 RUS80813.1 - 3.9e-07 30.7 0.1 7.3e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 TIR domain HEAT PF02985.22 RUS80813.1 - 4.8e-07 29.5 5.6 0.032 14.5 0.5 3.7 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 RUS80813.1 - 0.0021 18.1 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cbl_N2 PF02761.14 RUS80813.1 - 0.0094 16.6 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain HEAT_EZ PF13513.6 RUS80813.1 - 0.29 11.7 4.9 2.3 8.8 0.4 3.5 2 1 1 3 3 3 0 HEAT-like repeat UCH PF00443.29 RUS80815.1 - 2.3e-05 24.0 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vip3A_N PF12495.8 RUS80815.1 - 0.00065 19.6 0.9 0.00088 19.2 0.9 1.2 1 0 0 1 1 1 1 Vegetative insecticide protein 3A N terminal UCH PF00443.29 RUS80816.1 - 1.8e-05 24.4 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAP_GLY PF01302.25 RUS80818.1 - 5.6e-11 42.3 0.0 2.4e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 CAP-Gly domain Cast PF10174.9 RUS80818.1 - 0.11 10.6 52.1 0.36 9.0 52.1 1.6 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ParD_antitoxin PF03693.14 RUS80818.1 - 0.17 12.3 1.6 46 4.5 0.0 3.8 3 1 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Spc7 PF08317.11 RUS80818.1 - 3.4 6.5 55.7 0.3 9.9 25.5 3.1 1 1 3 4 4 4 0 Spc7 kinetochore protein HMMR_N PF15905.5 RUS80818.1 - 6.9 6.0 54.0 0.026 14.0 24.0 3.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 RUS80818.1 - 7.1 6.6 35.0 1.1 9.3 1.5 4.4 1 1 4 5 5 5 0 Laminin Domain II DUF1986 PF09342.11 RUS80819.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) PPTA PF01239.22 RUS80821.1 - 1.3e-53 177.2 19.5 5.3e-13 48.2 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 RUS80821.1 - 0.025 15.3 0.1 30 5.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SYCE1 PF15233.6 RUS80821.1 - 0.047 13.8 0.5 0.098 12.7 0.5 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF5598 PF18127.1 RUS80821.1 - 0.11 12.9 0.9 27 5.3 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5598) TPR_17 PF13431.6 RUS80821.1 - 0.41 11.1 6.7 7 7.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4219 PF13961.6 RUS80821.1 - 6 6.7 10.3 13 5.6 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) UPF0565 PF10561.9 RUS80822.1 - 4.1e-57 193.7 0.8 9.1e-34 117.0 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 hSac2 PF12456.8 RUS80823.1 - 7.2e-21 74.1 0.1 1.1e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Inositol phosphatase DUF5326 PF17260.2 RUS80824.1 - 0.28 11.3 2.0 0.49 10.6 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) HNF-1B_C PF04812.13 RUS80824.1 - 1.1 9.1 4.0 0.48 10.2 0.9 1.9 2 1 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Cornifin PF02389.15 RUS80827.1 - 5e-06 26.7 0.1 0.00087 19.5 0.4 2.4 1 1 1 2 2 2 1 Cornifin (SPRR) family Mg_chelatase PF01078.21 RUS80827.1 - 0.0027 17.1 0.7 8.2 5.7 0.0 5.0 2 1 5 7 7 7 1 Magnesium chelatase, subunit ChlI HU-CCDC81_bac_2 PF18175.1 RUS80827.1 - 0.03 14.2 0.0 18 5.3 0.0 4.3 2 1 2 4 4 4 0 CCDC81-like prokaryotic HU domain 2 YtfJ_HI0045 PF09695.10 RUS80827.1 - 0.046 13.4 0.0 16 5.1 0.0 3.9 2 2 3 5 5 5 0 Bacterial protein of unknown function (YtfJ_HI0045) DKCLD PF08068.12 RUS80827.1 - 0.077 13.1 24.3 77 3.5 0.1 11.4 5 3 10 15 15 15 0 DKCLD (NUC011) domain NlpE_C PF17185.4 RUS80827.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 NlpE C-terminal OB domain BUD22 PF09073.10 RUS80829.1 - 0.00029 20.3 43.7 0.00038 19.9 43.7 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 RUS80829.1 - 0.0035 16.8 45.2 0.0048 16.4 45.2 1.2 1 0 0 1 1 1 1 SDA1 BAF1_ABF1 PF04684.13 RUS80829.1 - 0.017 14.2 20.1 0.019 14.1 20.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor 7tm_1 PF00001.21 RUS80830.1 - 2.4e-14 53.3 13.9 4.3e-07 29.5 1.6 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS80830.1 - 8.5e-08 31.8 10.8 5.5e-06 25.9 5.5 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS80830.1 - 1.8e-05 24.3 2.4 1.8e-05 24.3 2.4 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx SNARE PF05739.19 RUS80830.1 - 0.074 13.1 1.6 0.17 11.9 1.6 1.6 1 0 0 1 1 1 0 SNARE domain DUF2208 PF09973.9 RUS80830.1 - 8.8 5.9 10.7 0.75 9.4 4.6 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF5343 PF17278.2 RUS80833.1 - 0.00096 19.3 0.3 0.28 11.3 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5343) Nab2 PF11517.8 RUS80833.1 - 0.0035 17.6 0.6 4.2 7.7 0.0 2.8 2 0 0 2 2 2 2 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) ATP-cone PF03477.16 RUS80833.1 - 0.007 16.9 4.0 0.35 11.5 0.2 2.8 2 1 0 2 2 2 1 ATP cone domain FDX-ACB PF03147.14 RUS80833.1 - 0.025 15.0 2.4 4 7.9 0.0 3.7 3 2 2 5 5 5 0 Ferredoxin-fold anticodon binding domain Sec31 PF11549.8 RUS80833.1 - 0.026 14.4 0.2 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein transport protein SEC31 BMFP PF04380.13 RUS80833.1 - 0.14 12.6 0.5 27 5.3 0.0 2.9 2 0 0 2 2 2 0 Membrane fusogenic activity PNPase PF03726.14 RUS80833.1 - 2.8 8.5 7.5 19 5.9 0.3 3.1 2 1 1 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3349 PF11829.8 RUS80833.1 - 6.8 7.5 8.5 31 5.4 0.3 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3349) Fasciclin PF02469.22 RUS80834.1 - 1.5e-40 138.4 0.0 3e-19 69.5 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain I_LWEQ PF01608.17 RUS80835.1 - 6.1e-34 117.5 3.7 6.1e-34 117.5 3.7 2.3 2 0 0 2 2 2 1 I/LWEQ domain GIT1_C PF12205.8 RUS80835.1 - 0.017 15.2 1.4 0.58 10.3 0.0 2.8 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term KORA PF16509.5 RUS80835.1 - 0.036 14.3 0.5 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor ApoLp-III PF07464.11 RUS80835.1 - 0.037 14.1 0.4 0.037 14.1 0.4 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DEP PF00610.21 RUS80835.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Laminin_I PF06008.14 RUS80835.1 - 0.2 11.3 4.2 0.068 12.9 1.5 1.6 2 0 0 2 2 2 0 Laminin Domain I DUF883 PF05957.13 RUS80835.1 - 5 7.8 7.6 4.9 7.8 0.2 3.2 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) I-set PF07679.16 RUS80836.1 - 3.2e-18 65.6 0.0 6.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS80836.1 - 1.1e-15 58.0 0.0 5e-15 55.9 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS80836.1 - 1.6e-12 47.6 0.0 3.9e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS80836.1 - 8.9e-11 41.8 0.5 2.7e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS80836.1 - 0.0052 16.9 0.1 0.023 14.9 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain SUIM_assoc PF16619.5 RUS80836.1 - 0.0058 16.7 8.9 0.035 14.2 8.9 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 EVC2_like PF12297.8 RUS80836.1 - 0.034 12.8 1.0 0.055 12.2 0.0 1.7 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Ig_4 PF16680.5 RUS80836.1 - 0.084 13.2 1.1 0.2 11.9 0.0 2.3 2 1 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain HemY_N PF07219.13 RUS80836.1 - 0.16 12.2 0.6 0.45 10.7 0.6 1.7 1 0 0 1 1 1 0 HemY protein N-terminus COX16 PF14138.6 RUS80836.1 - 0.33 11.5 1.4 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF4834 PF16118.5 RUS80836.1 - 3.6 8.6 7.5 26 5.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4381 PF14316.6 RUS80836.1 - 3.6 7.8 7.4 0.43 10.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-LITAF-like PF10601.9 RUS80838.1 - 1.2e-23 83.1 13.2 1.6e-23 82.7 13.2 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 RUS80838.1 - 1 9.4 6.2 13 5.9 6.2 2.2 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-C3HC4_3 PF13920.6 RUS80838.1 - 1.2 9.0 13.9 3.6 7.5 7.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.9 RUS80839.1 - 4.7e-20 71.6 21.2 4.7e-20 71.6 21.2 1.6 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain UNC-93 PF05978.16 RUS80840.1 - 2.2e-35 121.7 18.1 2.2e-35 121.7 18.1 4.5 4 1 0 4 4 4 2 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 RUS80840.1 - 2.5e-13 49.7 43.0 1.2e-09 37.6 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 RUS80841.1 - 1.4e-22 79.3 0.0 1.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS80841.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2457 PF10446.9 RUS80841.1 - 1.8 7.6 15.7 2.3 7.3 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tetraspanin PF00335.20 RUS80842.1 - 6.8e-11 42.3 0.2 7.7e-11 42.1 0.2 1.0 1 0 0 1 1 1 1 Tetraspanin family Ribosomal_S6e PF01092.19 RUS80844.1 - 1.9e-60 202.3 2.2 2.1e-60 202.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e Dynamitin PF04912.14 RUS80845.1 - 8.7e-110 367.7 22.0 9.8e-110 367.5 22.0 1.0 1 0 0 1 1 1 1 Dynamitin Peptidase_C11 PF03415.14 RUS80845.1 - 0.00075 19.0 2.1 0.0014 18.1 2.1 1.4 1 0 0 1 1 1 1 Clostripain family Sugarporin_N PF11471.8 RUS80845.1 - 0.0012 18.8 7.5 0.78 9.7 0.3 3.8 4 0 0 4 4 4 2 Maltoporin periplasmic N-terminal extension Leo1 PF04004.13 RUS80845.1 - 1 9.2 9.4 0.08 12.8 1.8 2.3 1 1 1 2 2 2 0 Leo1-like protein FAP206 PF12018.8 RUS80845.1 - 1.4 8.3 10.9 0.62 9.5 6.2 2.7 2 1 0 3 3 3 0 Domain of unknown function FapA PF03961.13 RUS80845.1 - 5 5.6 15.6 13 4.2 9.4 2.8 2 1 0 2 2 2 0 Flagellar Assembly Protein A Herpes_LMP2 PF07415.11 RUS80847.1 - 2.4 6.9 3.1 1.7 7.3 0.6 1.7 1 1 1 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2590 PF10761.9 RUS80847.1 - 2.7 8.2 5.5 39 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2590) AC_N PF16214.5 RUS80848.1 - 1.1e-20 74.2 1.0 1.6e-20 73.6 1.0 1.2 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 RUS80848.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding associated Sulfotransfer_1 PF00685.27 RUS80849.1 - 1.6e-14 54.1 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS80849.1 - 0.00018 21.9 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family LTXXQ PF07813.12 RUS80850.1 - 0.098 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein Reprolysin_5 PF13688.6 RUS80851.1 - 1.1e-10 42.0 0.0 2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS80851.1 - 2.1e-10 41.2 0.0 4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS80851.1 - 9.1e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 RUS80851.1 - 8.2e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS80851.1 - 1.7e-06 27.8 0.2 4.1e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS80851.1 - 0.00078 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 RUS80851.1 - 0.098 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 RUS80852.1 - 8e-11 42.4 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS80852.1 - 1.6e-10 41.6 0.0 3.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS80852.1 - 6.7e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 RUS80852.1 - 6.1e-07 29.5 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS80852.1 - 1.3e-06 28.2 0.2 3.2e-06 26.9 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS80852.1 - 0.00064 19.6 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 RUS80852.1 - 0.08 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family SPT16 PF08644.11 RUS80854.1 - 4.3e-58 195.8 1.2 1e-57 194.5 0.1 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 RUS80854.1 - 1.4e-49 168.0 5.8 2e-49 167.5 3.6 2.4 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RUS80854.1 - 4.8e-28 98.3 0.0 7.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 RUS80854.1 - 1.5e-18 67.0 2.1 3.4e-18 65.8 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like RRM_1 PF00076.22 RUS80855.1 - 9e-42 140.8 0.0 8.6e-24 83.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 RUS80855.1 - 8.7e-24 84.4 1.2 8.7e-24 84.4 1.2 2.2 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 RUS80855.1 - 0.00011 22.0 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 RUS80855.1 - 0.0039 16.8 0.0 0.24 11.0 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS80855.1 - 0.036 14.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Asp-Al_Ex PF06826.12 RUS80855.1 - 0.28 11.0 2.5 0.45 10.3 2.5 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region Presenilin PF01080.17 RUS80855.1 - 9 4.9 14.0 14 4.3 14.0 1.3 1 0 0 1 1 1 0 Presenilin ubiquitin PF00240.23 RUS80856.1 - 2e-23 81.9 0.1 2e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS80856.1 - 3.5e-13 49.2 0.1 3.9e-13 49.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS80856.1 - 9.7e-06 26.0 0.1 3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 RUS80856.1 - 2.4e-05 24.2 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Sedlin_N PF04628.13 RUS80857.1 - 1.6e-31 109.1 0.5 2.1e-31 108.8 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RUS80857.1 - 3.1e-10 40.2 0.1 3.6e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family TRAP_alpha PF03896.16 RUS80858.1 - 7.7e-111 369.9 0.1 9.6e-111 369.5 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_63N PF16923.5 RUS80859.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.0 2 1 0 3 3 3 0 Glycosyl hydrolase family 63 N-terminal domain Umbravirus_LDM PF04817.12 RUS80859.1 - 1.2 8.4 13.6 1.1 8.6 3.4 2.6 3 0 0 3 3 3 0 Umbravirus long distance movement (LDM) family AXH PF08517.12 RUS80861.1 - 7.8e-43 145.7 0.1 1.6e-42 144.7 0.1 1.6 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) RGCC PF15151.6 RUS80861.1 - 0.84 9.9 0.0 0.84 9.9 0.0 3.2 3 0 0 3 3 3 0 Response gene to complement 32 protein family Topoisom_I_N PF02919.15 RUS80862.1 - 4e-99 330.4 8.3 4e-99 330.4 8.3 4.0 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 RUS80862.1 - 8e-99 329.6 9.3 8e-99 329.6 9.3 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 RUS80862.1 - 8.3e-35 118.5 0.9 2.8e-34 116.9 0.9 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF3437 PF11919.8 RUS80862.1 - 0.23 11.4 1.7 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF1993 PF09351.10 RUS80862.1 - 4.2 7.5 6.5 14 5.8 5.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Epimerase PF01370.21 RUS80864.1 - 3.5e-34 118.4 0.0 4.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS80864.1 - 1.3e-27 97.0 0.0 1.8e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RUS80864.1 - 4.6e-20 71.8 0.0 6.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RUS80864.1 - 2.8e-18 66.0 0.0 3.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS80864.1 - 1e-09 38.0 0.0 4.9e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS80864.1 - 1.1e-09 37.8 0.1 7e-06 25.4 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 RUS80864.1 - 3.5e-06 27.0 0.0 1.4e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 RUS80864.1 - 0.0015 18.0 0.1 0.043 13.3 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 RUS80864.1 - 0.0028 17.3 0.1 0.21 11.1 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 RUS80864.1 - 0.024 14.5 0.4 0.96 9.3 0.4 2.3 2 0 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 RUS80864.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EGF_CA PF07645.15 RUS80866.1 - 7.2e-81 266.2 173.1 9.9e-10 38.5 6.3 11.8 11 1 0 11 11 11 10 Calcium-binding EGF domain cEGF PF12662.7 RUS80866.1 - 6.8e-53 176.2 106.5 3.2e-06 27.0 1.0 12.0 11 1 0 11 11 11 11 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS80866.1 - 1.6e-40 137.0 154.4 2.2e-07 31.0 13.0 11.9 11 0 0 11 11 11 10 EGF domain FXa_inhibition PF14670.6 RUS80866.1 - 2.3e-39 133.4 163.0 8.6e-12 45.1 9.1 11.7 9 2 2 11 11 11 11 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS80866.1 - 4.2e-25 87.7 157.2 0.00096 19.4 8.9 12.9 11 2 2 13 13 13 10 EGF-like domain hEGF PF12661.7 RUS80866.1 - 3.8e-21 74.9 151.7 0.00041 20.9 6.4 15.7 15 2 0 15 15 15 10 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 RUS80866.1 - 2.7e-18 66.0 125.2 0.0064 16.8 1.0 11.4 9 2 2 11 11 11 9 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 RUS80866.1 - 6.1e-08 32.6 128.8 0.0014 18.7 8.5 11.6 10 1 1 11 11 11 5 MSP1 EGF domain 1 CENP-B_dimeris PF09026.10 RUS80866.1 - 0.48 10.8 11.7 1.3 9.4 11.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1115 PF06544.12 RUS80866.1 - 5.4 7.1 5.3 9.9 6.3 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) FAM176 PF14851.6 RUS80866.1 - 7.4 6.2 11.0 13 5.4 11.0 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 RUS80867.1 - 0.0046 15.2 17.9 0.0056 15.0 17.9 1.0 1 0 0 1 1 1 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 RUS80867.1 - 0.013 15.7 25.8 0.022 15.0 25.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 RUS80867.1 - 0.05 14.2 1.9 0.084 13.5 1.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.12 RUS80867.1 - 0.4 10.0 36.3 0.59 9.4 36.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 RUS80867.1 - 0.74 8.6 5.2 0.94 8.3 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 RUS80867.1 - 1.1 7.3 33.5 1.3 7.0 33.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RUS80867.1 - 1.6 7.4 5.2 1.9 7.2 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RUS80867.1 - 2.1 6.5 19.5 2.6 6.3 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 RUS80867.1 - 3 6.9 40.3 4.7 6.2 40.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop53 PF07767.11 RUS80867.1 - 5 6.4 7.2 6.3 6.1 7.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) EGF_2 PF07974.13 RUS80868.1 - 9e-15 54.7 40.0 2e-05 24.8 2.7 3.2 2 1 1 3 3 3 3 EGF-like domain EGF PF00008.27 RUS80868.1 - 2.8e-11 43.5 43.3 8.1e-05 22.8 7.0 3.6 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 RUS80868.1 - 5.7e-07 29.9 48.5 0.00084 19.9 6.5 4.5 6 0 0 6 6 6 3 Human growth factor-like EGF DUF834 PF05754.14 RUS80869.1 - 0.18 11.8 8.1 17 5.5 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF834) LSPR PF06049.12 RUS80869.1 - 3.1 8.0 6.5 3.2e+02 1.9 0.1 4.6 4 0 0 4 4 4 0 Coagulation Factor V LSPD Repeat DAO PF01266.24 RUS80870.1 - 3.5e-38 132.1 0.0 4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 RUS80871.1 - 6e-39 134.6 0.1 7.6e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RUS80871.1 - 0.082 13.1 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS80871.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Med2 PF11214.8 RUS80871.1 - 0.24 11.6 0.0 0.43 10.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 ELL PF10390.9 RUS80872.1 - 5.3e-75 252.5 0.0 5.3e-75 252.5 0.0 1.8 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 RUS80872.1 - 1.3e-28 99.7 12.5 1.4e-28 99.6 11.1 1.8 2 0 0 2 2 2 1 Occludin homology domain Med9 PF07544.13 RUS80872.1 - 0.02 15.0 1.2 0.27 11.4 0.9 2.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 RUS80872.1 - 0.55 10.5 3.0 31 4.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 RUS80872.1 - 0.57 10.0 3.3 1.7 8.5 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator PRKG1_interact PF15898.5 RUS80872.1 - 4.6 8.2 10.2 0.6 11.0 2.9 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RQC PF09382.10 RUS80873.1 - 2.6e-26 91.6 0.2 5.5e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 RUS80873.1 - 1e-17 64.5 0.0 2.7e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RUS80873.1 - 2.2e-16 60.3 8.7 1e-15 58.2 8.7 2.3 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 RUS80873.1 - 3.1e-16 59.7 0.2 1.7e-15 57.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HRDC PF00570.23 RUS80873.1 - 1.4e-06 28.1 0.1 3.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 HRDC domain BKACE PF05853.12 RUS80873.1 - 0.00049 19.5 0.0 0.38 10.0 0.0 2.5 2 0 0 2 2 2 2 beta-keto acid cleavage enzyme Rgp1 PF08737.10 RUS80875.1 - 3e-43 148.6 0.0 1.2e-20 74.1 0.0 2.3 1 1 1 2 2 2 2 Rgp1 Arrestin_N PF00339.29 RUS80875.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF608 PF04685.13 RUS80876.1 - 3.2e-159 529.9 6.4 4.3e-159 529.5 6.4 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 RUS80876.1 - 4.7e-93 312.1 0.1 6.9e-93 311.5 0.1 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 RUS80876.1 - 0.0008 18.8 1.9 0.0014 17.9 1.9 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 RUS80876.1 - 0.0047 15.7 0.7 0.014 14.1 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase 36 superfamily, catalytic domain MAM33 PF02330.16 RUS80877.1 - 6.2e-23 81.9 0.2 9.1e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein BTB PF00651.31 RUS80878.1 - 3.2e-05 24.1 3.3 7.2e-05 23.0 0.0 3.4 5 0 0 5 5 5 1 BTB/POZ domain Arm PF00514.23 RUS80878.1 - 0.059 13.4 1.8 38 4.5 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2462 PF09495.10 RUS80879.1 - 3.2e-12 47.0 11.7 3.2e-12 47.0 11.7 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Diphthamide_syn PF01866.17 RUS80880.1 - 1.2e-120 402.6 0.0 1.4e-120 402.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF5331 PF17265.2 RUS80880.1 - 0.0037 17.0 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5331) PTH2 PF01981.16 RUS80881.1 - 1.6e-45 154.1 0.3 2.3e-45 153.6 0.3 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 cwf21 PF08312.12 RUS80882.1 - 3.5e-14 52.7 3.1 3.5e-14 52.7 3.1 2.2 2 0 0 2 2 2 1 cwf21 domain SRRM_C PF15230.6 RUS80882.1 - 2.2e-13 50.6 32.9 2.2e-13 50.6 32.9 6.3 2 2 3 5 5 5 1 Serine/arginine repetitive matrix protein C-terminus Sulfotransfer_1 PF00685.27 RUS80883.1 - 8.1e-48 163.2 0.1 4.5e-47 160.8 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS80883.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Trypsin_2 PF13365.6 RUS80884.1 - 0.00041 21.3 0.0 0.0006 20.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain CENP-B_dimeris PF09026.10 RUS80886.1 - 7.1 7.1 38.6 0.19 12.1 26.4 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pentapeptide_4 PF13599.6 RUS80888.1 - 1.2e-07 31.8 4.7 0.0036 17.4 0.4 3.4 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) DUF4443 PF14544.6 RUS80888.1 - 0.17 12.2 0.1 1e+02 3.2 0.0 4.3 2 2 4 6 6 6 0 Domain of unknown function (DUF4443) Fructosamin_kin PF03881.14 RUS80889.1 - 6.8e-39 133.8 0.1 9.4e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 RUS80889.1 - 0.00012 22.1 0.4 0.00016 21.7 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 RUS80889.1 - 0.0019 17.6 0.1 0.0027 17.1 0.1 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Rhodanese PF00581.20 RUS80890.1 - 3.3e-10 40.4 0.0 4e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain TPK_catalytic PF04263.16 RUS80890.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain zf-LITAF-like PF10601.9 RUS80891.1 - 1.8e-17 63.4 18.4 2.3e-17 63.0 18.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF1610 PF07754.11 RUS80891.1 - 0.0066 16.4 5.3 0.037 14.0 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.6 RUS80891.1 - 0.016 14.6 8.9 0.67 9.4 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 RUS80891.1 - 0.022 14.7 7.3 0.12 12.4 1.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L32p PF01783.23 RUS80891.1 - 0.025 14.8 1.0 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family CHU_C PF13585.6 RUS80892.1 - 9.4e-05 22.4 20.5 5.5e+02 0.7 0.0 11.0 2 1 3 6 6 6 0 C-terminal domain of CHU protein family Cornifin PF02389.15 RUS80892.1 - 0.08 13.1 0.0 19 5.5 0.0 2.3 1 1 1 2 2 2 0 Cornifin (SPRR) family Ank_3 PF13606.6 RUS80893.1 - 6.2e-08 32.3 3.4 4.6 8.1 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 RUS80893.1 - 1e-06 29.2 0.2 0.014 16.0 0.1 4.9 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS80893.1 - 1.3e-06 28.8 0.5 4 8.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS80893.1 - 1.4e-05 25.3 2.2 1.8 9.0 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS80893.1 - 0.0013 19.1 5.8 7.7 7.2 0.0 5.8 7 0 0 7 7 7 1 Ankyrin repeat RPN7 PF10602.9 RUS80893.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Sugar_tr PF00083.24 RUS80894.1 - 5.4e-31 107.9 16.9 7e-31 107.6 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS80894.1 - 1.2e-29 103.4 21.5 1.2e-29 103.4 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_7_1 PF16081.5 RUS80894.1 - 0.073 13.3 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family SpoVAC_SpoVAEB PF03862.13 RUS80894.1 - 1.7 8.9 10.2 0.25 11.6 5.2 2.2 2 0 0 2 2 2 0 SpoVAC/SpoVAEB sporulation membrane protein RNase_H PF00075.24 RUS80895.1 - 9.6e-06 25.8 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RT_RNaseH PF17917.1 RUS80895.1 - 0.0089 16.3 0.0 1.9 8.8 0.1 2.7 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 RUS80895.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like DUF1730 PF08331.10 RUS80895.1 - 0.19 11.7 0.4 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) Myb_DNA-bind_3 PF12776.7 RUS80895.1 - 0.56 11.2 4.4 2.7 9.0 0.0 3.1 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain UPF0164 PF03687.13 RUS80896.1 - 0.82 8.4 6.5 2.6 6.8 6.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0164) DUF5593 PF18007.1 RUS80897.1 - 0.89 10.3 9.7 8.5 7.1 2.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5593) Csm1_N PF18504.1 RUS80897.1 - 8.1 6.9 7.5 21 5.5 0.5 4.2 1 1 5 6 6 6 0 Csm1 N-terminal domain tRNA-synt_1d PF00750.19 RUS80898.1 - 1.3e-07 30.9 0.1 2.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DNA_pol_phi PF04931.13 RUS80898.1 - 1.7e-05 23.2 30.0 2.1e-05 22.9 30.0 1.4 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 RUS80898.1 - 0.00054 19.4 27.8 0.00067 19.1 27.8 1.2 1 0 0 1 1 1 1 BUD22 Na_trans_assoc PF06512.13 RUS80898.1 - 0.00079 19.8 14.8 0.0011 19.3 15.0 1.3 1 1 0 1 1 1 1 Sodium ion transport-associated SDA1 PF05285.12 RUS80898.1 - 0.00099 18.6 31.8 0.0012 18.3 31.8 1.3 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 RUS80898.1 - 0.0015 18.0 33.5 0.0027 17.1 33.5 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 RUS80898.1 - 0.005 15.9 37.7 0.0067 15.5 37.7 1.2 1 0 0 1 1 1 1 Paf1 PPP4R2 PF09184.11 RUS80898.1 - 0.0067 16.1 27.5 0.011 15.4 27.5 1.4 1 0 0 1 1 1 1 PPP4R2 SpoIIIAH PF12685.7 RUS80898.1 - 0.013 15.4 13.1 0.021 14.7 13.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 RUS80898.1 - 0.036 12.3 40.3 0.043 12.1 40.3 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_23 PF13476.6 RUS80898.1 - 0.058 13.9 20.6 0.086 13.3 20.6 1.3 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 RUS80898.1 - 0.091 11.0 31.9 0.12 10.7 31.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS80898.1 - 0.16 10.4 41.8 0.21 10.0 41.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4746 PF15928.5 RUS80898.1 - 0.19 11.2 32.8 0.29 10.5 32.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 RUS80898.1 - 0.31 11.2 7.6 0.47 10.6 7.6 1.4 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 RUS80898.1 - 0.34 10.8 15.9 0.48 10.4 15.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.6 RUS80898.1 - 0.43 9.3 11.4 0.59 8.8 11.4 1.2 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 RUS80898.1 - 0.45 9.2 18.0 0.52 9.0 18.0 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 RUS80898.1 - 0.51 10.8 14.6 0.92 9.9 14.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 RUS80898.1 - 0.55 10.0 28.0 0.81 9.5 28.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIP5K PF01504.18 RUS80898.1 - 0.92 8.7 6.2 1.1 8.4 6.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4045 PF13254.6 RUS80898.1 - 2 8.0 16.5 2.3 7.8 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ESM4 PF15952.5 RUS80898.1 - 2.9 8.3 14.4 5.6 7.4 14.4 1.5 1 0 0 1 1 1 0 Enhancer of split M4 family Neur_chan_memb PF02932.16 RUS80898.1 - 3.1 7.8 6.0 3.8 7.5 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 RUS80898.1 - 3.8 6.2 16.8 4.3 6.0 16.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 RUS80898.1 - 4.2 6.2 17.2 6 5.7 17.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Gti1_Pac2 PF09729.9 RUS80898.1 - 5.4 7.1 16.2 30 4.7 0.1 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2457 PF10446.9 RUS80898.1 - 5.9 5.9 43.6 9 5.3 43.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SID-1_RNA_chan PF13965.6 RUS80898.1 - 9.8 4.4 7.0 12 4.2 7.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AC_N PF16214.5 RUS80899.1 - 2.6e-67 227.8 3.8 2e-66 224.9 0.9 2.3 2 0 0 2 2 2 2 Adenylyl cyclase N-terminal extracellular and transmembrane region Guanylate_cyc PF00211.20 RUS80899.1 - 4.6e-58 195.8 0.3 2.1e-57 193.7 0.3 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain RVT_1 PF00078.27 RUS80900.1 - 3.2e-22 79.1 0.1 5.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ala_racemase_N PF01168.20 RUS80901.1 - 2.7e-16 59.9 0.0 3.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 RUS80901.1 - 9.9e-14 51.8 0.1 2.1e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 Putative serine dehydratase domain Cyclase PF04199.13 RUS80901.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative cyclase 7tm_1 PF00001.21 RUS80903.1 - 1.4e-06 27.9 3.3 0.0026 17.1 0.2 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) S1 PF00575.23 RUS80904.1 - 6.4e-51 170.6 7.3 5.2e-07 29.9 0.0 11.5 10 1 0 10 10 10 9 S1 RNA binding domain TPR_19 PF14559.6 RUS80904.1 - 4.9e-12 46.2 0.0 0.087 13.3 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Suf PF05843.14 RUS80904.1 - 7.3e-11 42.6 1.6 3e-06 27.5 0.1 4.3 2 1 1 5 5 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RUS80904.1 - 7.2e-07 29.5 0.0 7 7.8 0.0 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS80904.1 - 0.0014 19.2 0.0 2.4 8.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS80904.1 - 0.013 15.6 0.6 7 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 RUS80904.1 - 0.046 13.4 2.3 0.26 11.0 1.1 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 RUS80904.1 - 0.049 14.3 0.1 3.2 8.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS80904.1 - 0.12 12.7 0.2 7.8 6.9 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS80904.1 - 0.14 12.4 0.4 0.47 10.7 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RUS80904.1 - 0.17 12.2 0.7 36 4.9 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat ShK PF01549.24 RUS80905.1 - 6.2e-09 36.2 41.1 0.00019 21.9 10.1 5.5 6 0 0 6 6 6 4 ShK domain-like ShK PF01549.24 RUS80906.1 - 4.4e-17 62.3 36.8 1.3e-07 32.1 7.6 3.1 3 0 0 3 3 3 3 ShK domain-like ArenaCapSnatch PF17296.2 RUS80907.1 - 0.012 15.0 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Arenavirus cap snatching domain CsoS2_M PF12288.8 RUS80908.1 - 6.3e-09 35.8 17.2 2.5e-07 30.5 17.2 3.4 1 1 0 1 1 1 1 Carboxysome shell peptide mid-region HEAT PF02985.22 RUS80909.1 - 1.1e-41 137.3 27.4 0.00077 19.5 0.1 13.7 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 RUS80909.1 - 2.2e-38 130.5 10.8 7.7e-13 48.6 0.0 7.0 2 1 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 RUS80909.1 - 7e-11 42.6 3.3 0.15 12.7 0.0 6.8 2 1 6 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RUS80909.1 - 1.8e-10 41.1 12.1 0.055 14.0 0.0 9.1 9 1 2 11 11 11 2 HEAT-like repeat CLASP_N PF12348.8 RUS80909.1 - 1.1e-08 34.9 1.7 0.0033 17.0 0.1 4.7 2 2 3 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 RUS80909.1 - 1.3e-07 31.8 13.3 0.043 13.8 0.2 5.0 3 1 3 6 6 6 4 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 RUS80909.1 - 7.1e-05 23.1 0.7 1.7 9.0 0.0 5.1 3 2 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain Adaptin_N PF01602.20 RUS80909.1 - 8.6e-05 21.3 10.1 0.11 11.1 0.0 3.4 1 1 1 2 2 2 2 Adaptin N terminal region Nipped-B_C PF12830.7 RUS80909.1 - 0.027 14.4 0.6 1.3 8.9 0.1 2.9 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus V-ATPase_H_C PF11698.8 RUS80909.1 - 0.17 12.0 0.9 2.6 8.2 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H ECH_2 PF16113.5 RUS80911.1 - 3.1e-64 217.6 0.0 3.4e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RUS80911.1 - 2.8e-18 66.1 0.0 2.9e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4580 PF15162.6 RUS80912.1 - 3.1e-22 78.9 0.2 5.6e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4580) 7tm_1 PF00001.21 RUS80914.1 - 1.2e-64 218.2 0.1 3.2e-64 216.8 0.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS80914.1 - 2.5e-14 53.3 10.0 3.6e-12 46.2 3.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS80914.1 - 8.2e-09 35.5 6.7 8.2e-09 35.5 6.7 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS80914.1 - 6.2e-05 22.9 0.7 6.2e-05 22.9 0.7 1.9 2 0 0 2 2 2 1 Olfactory receptor Serglycin PF04360.12 RUS80914.1 - 0.00082 19.3 2.9 0.00082 19.3 2.9 2.1 2 0 0 2 2 2 1 Serglycin TMEM171 PF15471.6 RUS80914.1 - 0.11 11.5 7.6 0.035 13.1 2.0 2.8 3 0 0 3 3 3 0 Transmembrane protein family 171 FAIM1 PF06905.13 RUS80915.1 - 1.2e-11 44.6 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) PAPA-1 PF04795.12 RUS80915.1 - 0.0015 19.3 1.1 0.0022 18.7 1.1 1.2 1 0 0 1 1 1 1 PAPA-1-like conserved region RVT_1 PF00078.27 RUS80916.1 - 3e-10 40.0 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F_actin_bund_C PF18060.1 RUS80916.1 - 0.0037 17.4 2.0 0.87 9.8 0.2 2.2 2 0 0 2 2 2 2 F actin bundling C terminal YaaC PF14175.6 RUS80916.1 - 0.35 10.1 1.6 7.2 5.7 0.1 2.1 2 0 0 2 2 2 0 YaaC-like Protein Nop14 PF04147.12 RUS80917.1 - 0.72 8.0 45.1 1 7.5 45.1 1.3 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RUS80917.1 - 6.8 5.0 45.1 8.2 4.7 45.1 1.0 1 0 0 1 1 1 0 Mpp10 protein 7tm_1 PF00001.21 RUS80918.1 - 2.8e-20 72.8 13.6 3.6e-20 72.4 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cnl2_NKP2 PF09447.10 RUS80919.1 - 9.9 6.4 11.2 89 3.4 0.1 5.8 5 2 0 5 5 5 0 Cnl2/NKP2 family protein DHHC PF01529.20 RUS80921.1 - 3.1e-39 134.2 9.4 3.1e-39 134.2 9.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1218 PF06749.12 RUS80921.1 - 0.012 16.2 4.7 0.016 15.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) zf-UBR PF02207.20 RUS80921.1 - 0.026 14.7 5.7 0.055 13.6 5.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF2207 PF09972.9 RUS80921.1 - 0.18 10.5 0.2 2.8 6.6 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ephrin_rec_like PF07699.13 RUS80922.1 - 0.0035 17.1 2.5 0.0035 17.1 2.5 27.4 16 7 13 29 29 29 18 Putative ephrin-receptor like Fer4 PF00037.27 RUS80922.1 - 0.017 14.9 3.3 2.7 8.0 3.3 5.4 1 0 0 1 1 1 0 4Fe-4S binding domain Spore_Cse60 PF10957.8 RUS80922.1 - 0.24 11.5 2.9 12 6.0 0.3 2.9 2 0 0 2 2 2 0 Sporulation protein Cse60 Ephrin_rec_like PF07699.13 RUS80923.1 - 0.00033 20.3 3.2 0.00033 20.3 3.2 18.6 8 4 12 20 20 20 12 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80924.1 - 1.8e-09 37.2 158.8 4.3e-05 23.2 5.4 15.4 8 5 7 16 16 16 10 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80925.1 - 0.00095 18.9 103.5 0.0059 16.3 7.7 11.2 8 5 5 14 14 14 9 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80927.1 - 2e-09 37.1 121.4 0.00043 20.0 7.7 12.6 5 4 8 13 13 13 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 RUS80927.1 - 0.32 11.5 0.1 0.32 11.5 0.1 12.0 11 3 3 14 14 14 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS80928.1 - 0.21 11.4 22.9 0.16 11.8 4.4 4.8 1 1 3 5 5 5 0 Putative ephrin-receptor like Lustrin_cystein PF14625.6 RUS80928.1 - 8.6 6.8 24.7 39 4.7 0.2 4.5 1 1 3 4 4 4 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 RUS80929.1 - 0.14 11.9 122.6 0.26 11.1 1.4 13.9 3 3 9 13 13 13 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80930.1 - 9.6e-09 34.9 99.0 0.078 12.8 1.0 9.3 2 2 5 8 8 8 8 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 RUS80931.1 - 4.4e-31 106.4 161.1 2.2e-07 30.6 6.1 13.1 4 3 6 12 12 12 11 Putative ephrin-receptor like NCD3G PF07562.14 RUS80931.1 - 2.5e-05 24.1 116.5 0.052 13.5 6.2 13.1 8 3 2 12 12 12 10 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS80931.1 - 0.0023 18.3 123.1 0.14 12.6 0.6 15.2 8 5 6 14 14 14 11 TNFR/NGFR cysteine-rich region DUF4558 PF15104.6 RUS80932.1 - 4.1e-13 49.2 9.3 6.6e-13 48.5 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) PcfJ PF14284.6 RUS80932.1 - 0.3 11.0 5.1 0.6 10.0 5.1 1.6 1 1 0 1 1 1 0 PcfJ-like protein Sema PF01403.19 RUS80933.1 - 3.9e-89 299.4 0.0 4.9e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Sema domain I-set PF07679.16 RUS80933.1 - 8.5e-05 22.6 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS80933.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 RUS80933.1 - 0.0086 16.6 0.4 0.0086 16.6 0.4 2.2 2 0 0 2 2 2 1 Plexin repeat Syndecan PF01034.20 RUS80933.1 - 0.02 14.8 0.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Syndecan domain Adeno_E3_CR1 PF02440.15 RUS80933.1 - 0.039 13.7 0.1 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 DUF4200 PF13863.6 RUS80933.1 - 1.9 8.9 6.7 0.4 11.1 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OAD_gamma PF04277.13 RUS80934.1 - 1.3 9.6 4.6 2.5 8.8 4.6 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Lectin_C PF00059.21 RUS80935.1 - 2.6e-15 57.0 0.0 6.9e-15 55.7 0.0 1.6 2 0 0 2 2 2 1 Lectin C-type domain Viral_RdRp_C PF17501.2 RUS80935.1 - 0.079 13.4 0.8 0.16 12.5 0.8 1.4 1 0 0 1 1 1 0 Viral RNA-directed RNA polymerase GCOM2 PF15328.6 RUS80936.1 - 2.5e-08 34.6 13.3 3.9e-07 30.7 13.3 2.7 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 PLU-1 PF08429.11 RUS80936.1 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 PLU-1-like protein Malate_synthase PF01274.22 RUS80936.1 - 0.046 12.0 0.2 0.08 11.2 0.1 1.3 1 1 0 1 1 1 0 Malate synthase FF PF01846.19 RUS80937.1 - 3e-38 129.8 31.6 1.6e-13 50.6 0.0 7.2 8 0 0 8 8 8 5 FF domain WW PF00397.26 RUS80937.1 - 5.3e-20 71.2 12.7 2.5e-10 40.3 1.8 2.9 2 0 0 2 2 2 2 WW domain LUD_dom PF02589.15 RUS80937.1 - 0.29 10.8 1.6 0.87 9.3 1.6 1.7 1 0 0 1 1 1 0 LUD domain EamA PF00892.20 RUS80938.1 - 6.5e-13 49.0 27.6 5.2e-07 29.9 11.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 RUS80938.1 - 3e-07 30.0 1.3 3e-07 30.0 1.3 2.4 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 RUS80938.1 - 0.058 12.3 4.0 0.037 13.0 0.6 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 RUS80938.1 - 0.093 12.2 7.7 0.069 12.6 4.2 2.5 2 1 0 2 2 2 0 Solute carrier family 35 TFIIA PF03153.13 RUS80940.1 - 0.072 13.1 22.3 0.076 13.0 22.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 RUS80940.1 - 0.27 10.0 2.3 0.23 10.2 2.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS80940.1 - 0.39 8.9 27.1 0.49 8.6 27.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS80940.1 - 2.8 6.1 24.6 3.7 5.7 24.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 RUS80941.1 - 0.0084 16.0 0.5 0.0097 15.8 0.5 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Rhabdo_ncap PF00945.18 RUS80941.1 - 0.084 11.7 2.6 0.094 11.6 2.6 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Astro_capsid_p PF12226.8 RUS80941.1 - 0.088 11.9 20.1 0.087 12.0 20.1 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 RUS80941.1 - 0.12 11.5 7.3 0.12 11.6 7.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 RUS80941.1 - 1.1 7.2 7.2 1.2 7.1 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 RUS80941.1 - 1.5 7.0 20.0 1.6 6.9 20.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS80941.1 - 2.9 6.1 17.8 3.4 5.9 17.8 1.0 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 RUS80941.1 - 4.6 4.9 7.3 4.6 4.9 7.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 RUS80941.1 - 5.8 6.8 15.9 6.7 6.5 15.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 RUS80941.1 - 8.2 5.7 23.9 9.1 5.6 23.9 1.0 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 RUS80944.1 - 1.4e-59 201.7 0.0 3.1e-59 200.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS80944.1 - 1.7e-26 93.1 0.0 3.7e-26 92.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS80944.1 - 2.4e-05 23.8 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS80944.1 - 0.00013 22.0 0.0 0.049 13.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RUS80944.1 - 0.19 10.8 0.0 0.4 9.7 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 FAIM1 PF06905.13 RUS80945.1 - 5.7e-06 26.2 0.0 7.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Connexin PF00029.19 RUS80946.1 - 0.0016 18.3 7.5 0.0016 18.3 7.5 2.1 2 0 0 2 2 2 1 Connexin DUF4604 PF15377.6 RUS80946.1 - 0.0036 17.7 29.7 0.0036 17.7 29.7 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) RNA_pol_Rpc4 PF05132.14 RUS80946.1 - 0.018 15.4 8.2 0.018 15.4 8.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS80946.1 - 0.024 13.4 13.1 0.029 13.1 13.1 1.2 1 0 0 1 1 1 0 Presenilin DUF3246 PF11596.8 RUS80946.1 - 0.11 12.0 0.5 0.17 11.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SLC12 PF03522.15 RUS80946.1 - 0.17 10.9 16.2 0.26 10.3 16.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 RUS80946.1 - 0.21 10.5 16.0 0.28 10.1 16.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Methyltransf_32 PF13679.6 RUS80946.1 - 1.1 9.2 8.2 0.26 11.3 3.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain SART-1 PF03343.13 RUS80946.1 - 1.2 7.7 41.6 1.6 7.2 23.0 2.2 1 1 1 2 2 2 0 SART-1 family Pox_Ag35 PF03286.14 RUS80946.1 - 1.2 8.9 35.5 6.7e+03 -3.3 35.5 2.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein BT1 PF03092.16 RUS80946.1 - 2 6.5 3.2 3.2 5.9 3.2 1.4 1 0 0 1 1 1 0 BT1 family Neur_chan_memb PF02932.16 RUS80946.1 - 4.9 7.1 11.6 6.9 6.7 11.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1764 PF08576.10 RUS80946.1 - 5.3 8.0 36.3 2.1 9.3 20.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Eapp_C PF10238.9 RUS80946.1 - 6.3 6.9 25.2 4.4 7.4 13.9 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein PH PF00169.29 RUS80947.1 - 0.0014 19.1 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 PH domain DAGK_acc PF00609.19 RUS80948.1 - 1.9e-51 174.6 0.0 4.4e-51 173.4 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain SAM_1 PF00536.30 RUS80948.1 - 3e-20 72.4 1.0 1.4e-19 70.3 0.2 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS80948.1 - 3.3e-18 65.5 0.2 9.7e-18 64.0 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 RUS80948.1 - 2.3e-15 56.2 36.4 2.7e-09 36.8 6.2 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RUS80948.1 - 0.00062 20.0 16.9 0.02 15.2 6.5 2.7 2 0 0 2 2 2 2 C1 domain DEAD PF00270.29 RUS80949.1 - 5.2e-46 156.6 0.1 8.9e-46 155.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS80949.1 - 2.9e-33 114.5 0.3 9.5e-32 109.6 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS80949.1 - 8.8e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RUS80949.1 - 0.00023 21.5 0.1 0.0025 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS80949.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 RUS80949.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 RUS80949.1 - 0.029 14.6 0.3 0.15 12.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 RUS80949.1 - 0.049 13.6 0.1 0.7 9.9 0.0 2.4 2 1 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.25 RUS80949.1 - 0.077 12.3 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.21 RUS80949.1 - 0.12 11.9 0.1 0.16 11.4 0.1 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 RUS80949.1 - 0.12 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.22 RUS80950.1 - 3.9e-60 199.6 0.0 1.6e-20 72.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS80950.1 - 4.5e-09 36.0 0.0 0.00034 20.2 0.0 3.8 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS80950.1 - 0.00039 20.4 0.0 0.15 12.1 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 RUS80950.1 - 0.0031 17.3 0.0 4.2 7.3 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Peptidase_M14 PF00246.24 RUS80951.1 - 7.4e-24 85.0 0.0 2.6e-23 83.3 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 RUS80951.1 - 1.4e-13 51.1 0.2 2.5e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 RUS80951.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family 4HBT PF03061.22 RUS80953.1 - 1.3e-15 57.5 0.1 2.2e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 RUS80953.1 - 6.1e-06 26.7 0.1 1e-05 26.0 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Galactosyl_T PF01762.21 RUS80954.1 - 4e-42 144.2 0.0 5.3e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS80954.1 - 4.8e-06 26.2 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Mpv17_PMP22 PF04117.12 RUS80955.1 - 1.7e-16 60.1 1.8 3.3e-16 59.3 1.8 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family CcmD PF04995.14 RUS80955.1 - 0.075 13.1 0.2 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Lipase PF00151.19 RUS80956.1 - 7.3e-34 117.6 0.5 1.5e-28 100.1 0.0 2.0 1 1 1 2 2 2 2 Lipase Abhydrolase_6 PF12697.7 RUS80956.1 - 1e-05 26.2 0.5 1e-05 26.2 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS80956.1 - 0.026 13.8 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 RUS80956.1 - 0.03 13.8 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 RUS80956.1 - 0.06 13.0 0.3 0.17 11.5 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 RUS80956.1 - 0.22 11.6 0.4 0.45 10.6 0.3 1.5 1 1 0 1 1 1 0 Thioesterase domain DEP PF00610.21 RUS80958.1 - 1e-10 41.5 0.1 2.7e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 RUS80958.1 - 0.0003 20.6 0.4 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain Neuromodulin_N PF10580.9 RUS80958.1 - 0.11 12.3 2.4 0.24 11.2 2.4 1.5 1 0 0 1 1 1 0 Gap junction protein N-terminal region Oxysterol_BP PF01237.18 RUS80959.1 - 7.8e-82 275.1 4.3 7.1e-80 268.6 4.3 2.4 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 RUS80959.1 - 2e-05 25.1 0.1 0.00011 22.7 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RUS80959.1 - 0.0011 19.4 0.4 0.0039 17.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 RUS80959.1 - 0.025 14.9 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 RUS80959.1 - 0.67 10.3 2.7 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain JmjC PF02373.22 RUS80961.1 - 8.1e-43 145.5 0.2 8.1e-43 145.5 0.2 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 RUS80961.1 - 8.1e-23 80.7 5.9 8.1e-23 80.7 5.9 3.3 3 0 0 3 3 3 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 RUS80961.1 - 1.8e-16 59.5 0.5 3.3e-10 39.5 0.2 2.5 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain JmjN PF02375.17 RUS80961.1 - 4.8e-13 48.8 0.6 1e-12 47.8 0.6 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 RUS80961.1 - 4.6e-12 46.0 3.7 4.6e-12 46.0 3.7 3.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RUS80961.1 - 4.8e-09 35.6 6.9 4.8e-09 35.6 6.9 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RUS80961.1 - 3.9e-06 26.7 16.0 5.3e-05 23.0 4.0 3.4 2 0 0 2 2 2 2 PHD-finger Tudor_3 PF18115.1 RUS80961.1 - 0.00016 21.4 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 RUS80961.1 - 0.07 13.2 0.1 0.76 9.8 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) RPEL PF02755.15 RUS80962.1 - 1.4e-23 81.8 17.8 6.3e-07 28.9 3.6 4.4 4 0 0 4 4 4 4 RPEL repeat PDZ PF00595.24 RUS80964.1 - 6.8e-21 74.4 1.0 1.1e-11 44.9 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS80964.1 - 8.9e-18 63.9 0.2 1e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS80964.1 - 1.3e-08 35.0 0.1 1.7e-06 28.3 0.0 2.6 1 1 1 2 2 2 2 PDZ domain AAA_6 PF12774.7 RUS80966.1 - 1.1e-145 484.8 0.0 1.2e-144 481.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS80966.1 - 1.5e-129 432.6 0.0 1.5e-129 432.6 0.0 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RUS80966.1 - 1.3e-113 379.3 0.5 3.9e-113 377.7 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RUS80966.1 - 3.5e-103 344.5 0.4 2e-101 338.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RUS80966.1 - 1.1e-82 276.4 0.5 1.1e-81 273.2 1.1 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RUS80966.1 - 3.1e-80 268.0 0.0 6.3e-78 260.4 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RUS80966.1 - 1.5e-58 197.3 0.1 6.3e-58 195.2 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RUS80966.1 - 4.6e-46 157.4 10.9 4.6e-46 157.4 10.9 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS80966.1 - 4.9e-46 155.7 0.0 2.9e-43 146.7 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RUS80966.1 - 1.1e-19 70.7 0.0 5.4e-06 26.4 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RUS80966.1 - 3.6e-19 68.8 0.1 3.6e-18 65.6 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RUS80966.1 - 1.1e-15 57.8 0.0 1.1e-14 54.6 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RUS80966.1 - 9.4e-08 32.5 0.1 0.047 14.1 0.0 5.0 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS80966.1 - 0.00034 20.9 0.5 1.5 9.1 0.0 5.0 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.6 RUS80966.1 - 0.00036 21.1 0.9 0.084 13.4 0.0 4.6 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 RUS80966.1 - 0.0027 18.1 0.0 6.4 7.2 0.0 3.6 4 0 0 4 4 3 1 RNA helicase T2SSE PF00437.20 RUS80966.1 - 0.005 15.9 2.0 0.43 9.6 0.0 3.6 4 0 0 4 4 4 1 Type II/IV secretion system protein PMEI PF04043.15 RUS80966.1 - 0.007 16.7 6.9 0.88 9.9 0.8 2.7 2 0 0 2 2 2 2 Plant invertase/pectin methylesterase inhibitor AAA_16 PF13191.6 RUS80966.1 - 0.015 15.7 0.1 15 5.9 0.0 4.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 RUS80966.1 - 0.13 12.5 0.1 3.4 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RUS80966.1 - 1.5 8.5 3.6 2.8 7.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain Peptidase_C1 PF00112.23 RUS80967.1 - 1.7e-70 237.5 0.5 2.5e-70 237.0 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RUS80967.1 - 9.7e-09 35.5 1.5 2.6e-08 34.2 1.5 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RUS80967.1 - 0.012 14.5 1.0 0.19 10.5 0.3 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Tetraspanin PF00335.20 RUS80968.1 - 5.9e-39 134.1 1.9 7.3e-39 133.8 1.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Abhydrolase_9_N PF15420.6 RUS80968.1 - 0.062 13.3 2.2 0.086 12.8 0.3 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3382 PF11862.8 RUS80968.1 - 0.11 12.8 2.9 0.38 11.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Swi6_N PF18530.1 RUS80968.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Swi6 N-terminal domain Saf_2TM PF18303.1 RUS80968.1 - 0.5 9.9 0.0 0.5 9.9 0.0 2.8 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain CD20 PF04103.15 RUS80968.1 - 2.8 8.0 13.5 0.28 11.3 4.1 3.1 2 1 1 3 3 3 0 CD20-like family DUF4064 PF13273.6 RUS80968.1 - 4.5 7.6 15.5 15 5.9 6.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Globin PF00042.22 RUS80969.1 - 1.3e-19 70.8 0.1 1.6e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Globin SCAB_CC PF16712.5 RUS80969.1 - 0.067 13.0 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein MFS_1 PF07690.16 RUS80970.1 - 0.0011 18.0 43.1 0.0049 15.8 19.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily US10 PF17617.2 RUS80970.1 - 4.6 7.3 5.8 0.77 9.8 1.3 2.1 2 0 0 2 2 2 0 Viral unique short region 10 MFS_1 PF07690.16 RUS80971.1 - 1.2e-09 37.5 0.4 1.2e-09 37.5 0.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CTNNB1_binding PF08347.11 RUS80971.1 - 0.049 13.8 0.4 0.068 13.4 0.4 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding LapA_dom PF06305.11 RUS80971.1 - 1.6 8.6 4.5 0.9 9.4 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 RUS80972.1 - 3.2e-26 92.5 0.1 7.3e-26 91.3 0.1 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RUS80972.1 - 8e-09 35.7 0.7 0.00084 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 RUS80972.1 - 5.9e-06 25.8 0.9 9e-06 25.3 0.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 RUS80972.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RUS80972.1 - 0.0018 18.7 0.2 0.0029 18.0 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS80972.1 - 0.0018 18.0 0.8 0.0036 17.0 0.8 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RUS80972.1 - 0.0032 16.9 0.2 0.048 13.1 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS80972.1 - 0.029 14.9 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RUS80972.1 - 0.033 13.9 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RUS80972.1 - 0.072 12.8 0.3 0.16 11.7 0.2 1.6 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 RUS80972.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 RUS80972.1 - 0.14 11.7 1.1 0.54 9.8 0.7 2.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RUS80972.1 - 0.37 11.1 1.7 4 7.7 1.7 2.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS80974.1 - 1.4e-27 96.8 0.1 3.2e-27 95.7 0.1 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 RUS80974.1 - 1.5e-22 80.0 13.3 2.2e-22 79.5 13.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 RUS80974.1 - 8.3e-09 35.7 0.5 0.00057 19.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RUS80974.1 - 0.00029 20.8 0.1 0.00058 19.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 RUS80974.1 - 0.00052 19.7 0.6 0.0011 18.6 0.6 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RUS80974.1 - 0.0013 18.2 0.2 0.03 13.8 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RUS80974.1 - 0.0014 19.0 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PDR_CDR PF06422.12 RUS80974.1 - 0.004 17.0 0.0 0.004 17.0 0.0 2.0 2 0 0 2 2 1 1 CDR ABC transporter AAA_23 PF13476.6 RUS80974.1 - 0.01 16.4 0.2 0.018 15.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RUS80974.1 - 0.021 14.5 0.5 0.13 12.0 0.2 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RUS80974.1 - 0.032 14.0 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain FR47 PF08445.10 RUS80975.1 - 8.4e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RUS80975.1 - 7e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS80975.1 - 1.6e-06 28.3 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Gly_acyl_tr_N PF06021.11 RUS80975.1 - 1e-05 25.8 0.0 0.00017 21.8 0.0 2.0 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Acetyltransf_7 PF13508.7 RUS80975.1 - 3.9e-05 24.0 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RUS80975.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sel1 PF08238.12 RUS80976.1 - 1.1e-51 172.1 30.0 2.5e-09 37.5 0.1 11.9 12 0 0 12 12 12 9 Sel1 repeat 7tm_1 PF00001.21 RUS80977.1 - 1.9e-27 96.3 15.6 1.9e-27 96.3 15.6 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS80977.1 - 0.0002 21.1 9.1 0.0002 21.1 9.1 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS80977.1 - 1.4 8.3 19.0 12 5.2 19.0 2.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Orf78 PF06024.12 RUS80977.1 - 7.1 7.0 9.0 3.3 8.1 1.4 2.9 2 1 1 3 3 3 0 Orf78 (ac78) ABC2_membrane PF01061.24 RUS80978.1 - 4e-18 65.6 16.8 6.7e-18 64.9 16.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RUS80978.1 - 1.1e-16 61.7 0.1 2e-15 57.5 0.0 2.2 1 1 1 2 2 2 1 ABC transporter AAA_29 PF13555.6 RUS80978.1 - 0.00024 20.8 0.2 0.00046 19.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS80978.1 - 0.00031 20.7 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RUS80978.1 - 0.00037 20.9 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 RUS80978.1 - 0.0026 17.6 8.8 0.0031 17.4 0.2 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RUS80978.1 - 0.0027 18.3 0.0 0.0045 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 RUS80978.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 RUS80978.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RUS80978.1 - 0.03 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 RUS80978.1 - 0.096 12.1 0.2 0.21 11.0 0.1 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Utp14 PF04615.13 RUS80978.1 - 0.11 11.1 4.2 0.14 10.7 4.2 1.1 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 RUS80978.1 - 2.6 7.3 9.5 3.7 6.8 9.5 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RUS80978.1 - 4.5 5.2 28.9 6.5 4.7 28.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fe-S_biosyn PF01521.20 RUS80979.1 - 1.9e-16 60.2 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF228 PF02989.14 RUS80979.1 - 0.00071 19.4 0.2 0.0017 18.2 0.2 1.6 1 1 1 2 2 2 1 Lyme disease proteins of unknown function DUF3899 PF13038.6 RUS80980.1 - 0.013 16.0 1.3 0.015 15.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) SPT_ssu-like PF11779.8 RUS80981.1 - 0.049 13.2 0.3 0.077 12.6 0.3 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Trehalose_recp PF06151.13 RUS80983.1 - 4.9e-05 22.1 9.3 8.1e-05 21.4 9.3 1.3 1 0 0 1 1 1 1 Trehalose receptor EF-hand_1 PF00036.32 RUS80984.1 - 4e-54 176.2 23.2 2.5e-09 36.0 0.1 6.5 6 1 1 7 7 6 6 EF hand EF-hand_7 PF13499.6 RUS80984.1 - 2.7e-47 159.1 10.4 1.4e-16 60.7 0.9 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS80984.1 - 9.4e-42 137.4 16.5 1.2e-08 34.2 0.0 6.9 6 1 1 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 RUS80984.1 - 3.2e-39 132.5 22.4 1.2e-12 47.5 0.4 6.0 2 1 5 7 7 6 6 EF-hand domain pair EF-hand_5 PF13202.6 RUS80984.1 - 9.3e-36 119.8 19.7 1.7e-06 27.2 0.0 6.4 5 1 1 6 6 6 6 EF hand EF-hand_9 PF14658.6 RUS80984.1 - 2e-21 76.1 0.6 1e-06 29.0 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS80984.1 - 6e-12 45.9 0.5 0.0042 17.4 0.2 3.2 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS80984.1 - 2.2e-10 40.4 5.9 0.0032 17.4 0.3 4.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS80984.1 - 4.1e-07 30.1 4.1 0.77 9.7 0.0 4.9 2 2 3 5 5 5 2 Caleosin related protein EF-hand_11 PF08976.11 RUS80984.1 - 5.5e-07 30.4 0.2 0.076 13.9 0.1 3.1 1 1 2 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 RUS80984.1 - 1.3e-06 28.5 12.6 0.0053 16.9 1.8 4.5 2 2 3 5 5 5 3 Dockerin type I domain UPF0154 PF03672.13 RUS80984.1 - 1.5e-06 28.1 2.2 0.11 12.6 0.0 3.9 5 0 0 5 5 3 1 Uncharacterised protein family (UPF0154) TerB PF05099.13 RUS80984.1 - 1e-05 25.5 6.0 0.17 11.9 0.0 3.9 2 1 2 4 4 4 3 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 RUS80984.1 - 4e-05 23.9 0.6 0.075 13.4 0.0 3.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF4497 PF14924.6 RUS80984.1 - 5.4e-05 23.6 0.1 1.2 9.7 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF4497) SapB_1 PF05184.15 RUS80984.1 - 0.00082 19.3 1.3 4 7.5 0.0 3.8 4 0 0 4 4 3 1 Saposin-like type B, region 1 PMBR PF09373.10 RUS80984.1 - 0.0035 17.4 0.2 26 5.2 0.0 5.2 7 0 0 7 7 6 0 Pseudomurein-binding repeat Staphylokinase PF02821.16 RUS80984.1 - 0.0065 16.9 1.4 5.5 7.4 0.0 3.6 1 1 3 4 4 4 1 Staphylokinase/Streptokinase family DUF5132 PF17195.4 RUS80984.1 - 0.01 15.9 1.1 8.5 6.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) EF-hand_14 PF17959.1 RUS80984.1 - 0.01 16.2 0.9 20 5.6 0.0 3.5 1 1 1 3 3 3 0 EF-hand domain PY_rept_46 PF09689.10 RUS80984.1 - 0.023 15.2 0.6 7.3 7.2 0.1 3.7 3 0 0 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) SurA_N_2 PF13623.6 RUS80984.1 - 0.025 14.5 6.0 0.17 11.7 1.8 3.2 1 1 2 3 3 3 0 SurA N-terminal domain EFhand_Ca_insen PF08726.10 RUS80984.1 - 0.025 14.7 3.5 4 7.6 0.1 4.1 3 2 1 4 4 4 0 Ca2+ insensitive EF hand UBA_6 PF18039.1 RUS80984.1 - 0.072 13.0 1.1 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 UBA-like domain DUF5580 PF17743.1 RUS80984.1 - 0.085 11.4 0.0 0.28 9.7 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF1811 PF08838.10 RUS80984.1 - 0.11 12.8 0.1 59 4.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) HMG_box_2 PF09011.10 RUS80984.1 - 0.12 12.9 0.1 5.3 7.7 0.0 2.8 3 0 0 3 3 2 0 HMG-box domain DED PF01335.21 RUS80984.1 - 0.13 12.6 1.9 0.32 11.3 0.1 2.6 4 0 0 4 4 2 0 Death effector domain SurA_N_3 PF13624.6 RUS80984.1 - 0.19 11.5 4.9 0.23 11.2 1.2 2.5 1 1 1 3 3 3 0 SurA N-terminal domain SLATT_1 PF18181.1 RUS80984.1 - 0.43 10.5 0.9 91 3.0 0.0 3.5 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 DUF327 PF03885.13 RUS80984.1 - 0.48 10.4 6.7 6.8 6.7 0.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF327) LRR_8 PF13855.6 RUS80985.1 - 1.9e-13 50.0 8.9 1.2e-07 31.3 1.8 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 RUS80985.1 - 4.9e-05 23.1 2.3 0.16 12.1 0.4 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 RUS80985.1 - 0.00089 19.6 1.8 0.83 10.2 0.3 3.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS80985.1 - 0.0018 18.6 1.6 0.44 11.3 0.1 3.4 3 1 0 3 3 3 1 Leucine Rich Repeat CDKN3 PF05706.12 RUS80986.1 - 8.3e-45 152.4 0.5 1.1e-44 152.1 0.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 RUS80986.1 - 1.1e-06 28.5 0.1 1.6e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS80986.1 - 0.0018 17.9 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RUS80986.1 - 0.037 14.1 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40_like PF17005.5 RUS80986.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain zf-C2H2 PF00096.26 RUS80987.1 - 1.1e-11 44.5 54.3 4.8e-05 23.6 5.3 7.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS80987.1 - 8.5e-11 41.7 56.8 0.0054 17.5 3.6 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS80987.1 - 8.4e-09 35.5 36.7 0.024 15.1 0.6 6.8 6 0 0 6 6 6 5 Zinc-finger double domain FLYWCH PF04500.16 RUS80987.1 - 4.6e-05 23.4 0.4 0.00013 21.9 0.4 1.8 1 0 0 1 1 1 1 FLYWCH zinc finger domain zf-C2H2_6 PF13912.6 RUS80987.1 - 0.0069 16.4 2.8 0.0069 16.4 2.8 5.9 6 0 0 6 6 5 1 C2H2-type zinc finger Elf1 PF05129.13 RUS80987.1 - 0.0082 16.2 2.2 0.0082 16.2 2.2 3.9 1 1 2 3 3 3 2 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 RUS80987.1 - 0.042 13.7 0.6 0.042 13.7 0.6 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 RUS80987.1 - 0.045 14.0 1.1 0.045 14.0 1.1 6.3 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF2321 PF10083.9 RUS80987.1 - 0.11 12.1 14.0 0.41 10.3 0.8 3.1 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) FoP_duplication PF13865.6 RUS80987.1 - 1.7 9.2 4.5 3 8.4 0.4 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zinc_ribbon_9 PF14369.6 RUS80987.1 - 3.3 8.1 10.6 14 6.1 2.9 3.9 3 0 0 3 3 3 0 zinc-ribbon ADK_lid PF05191.14 RUS80987.1 - 6.4 6.9 12.9 3.4 7.7 0.7 4.0 3 1 1 4 4 4 0 Adenylate kinase, active site lid Myb_DNA-binding PF00249.31 RUS80988.1 - 7.4e-10 38.9 0.1 1.7e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 RUS80988.1 - 2e-08 33.9 6.3 2e-08 33.9 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 RUS80988.1 - 7.5e-06 26.1 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 RUS80988.1 - 0.0055 17.0 8.2 0.013 15.8 8.2 1.6 1 0 0 1 1 1 1 C1 domain SWIRM PF04433.17 RUS80988.1 - 0.052 13.9 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 SWIRM domain MFS_1 PF07690.16 RUS80989.1 - 9.1e-21 74.2 27.2 9.9e-14 51.0 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_transport PF06800.12 RUS80989.1 - 0.0014 18.0 1.4 0.0014 18.0 1.4 2.2 2 0 0 2 2 2 1 Sugar transport protein MFS_3 PF05977.13 RUS80989.1 - 0.014 13.8 10.2 0.039 12.3 2.2 2.7 2 1 0 2 2 2 0 Transmembrane secretion effector DUF5337 PF17272.2 RUS80989.1 - 0.2 11.5 1.1 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5337) 7TM_GPCR_Srw PF10324.9 RUS80990.1 - 4e-08 32.9 19.3 2.3e-07 30.4 19.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS80990.1 - 1.4e-05 24.6 15.3 2.1e-05 24.0 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS80991.1 - 2e-09 37.2 16.4 3.4e-09 36.4 16.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS80991.1 - 4.4e-05 23.0 15.3 6.5e-05 22.4 15.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS80991.1 - 4.8e-05 22.8 13.2 6.2e-05 22.5 13.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS80991.1 - 0.0023 17.6 20.3 0.019 14.6 20.4 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx fn3 PF00041.21 RUS80992.1 - 9e-06 26.0 1.5 0.21 11.9 0.0 3.4 3 1 0 3 3 3 2 Fibronectin type III domain Collagen PF01391.18 RUS80994.1 - 0.0019 17.9 79.5 0.0023 17.6 17.2 5.3 3 1 1 4 4 4 2 Collagen triple helix repeat (20 copies) Ldl_recept_a PF00057.18 RUS80995.1 - 6.1e-09 35.9 25.0 4.2e-06 26.9 8.1 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 RUS80995.1 - 2.5 7.9 10.3 2.8 7.7 1.4 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like CUB PF00431.20 RUS80996.1 - 0.078 13.3 0.2 0.24 11.7 0.0 1.7 1 1 0 2 2 2 0 CUB domain EGF_CA PF07645.15 RUS80997.1 - 1.4e-10 41.2 7.9 5.3e-10 39.3 7.9 2.1 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 RUS80997.1 - 9.5e-05 22.5 10.0 0.00022 21.4 4.8 2.6 2 0 0 2 2 2 1 EGF domain hEGF PF12661.7 RUS80997.1 - 0.037 14.7 2.0 0.037 14.7 2.0 2.6 3 0 0 3 3 3 0 Human growth factor-like EGF DUF3829 PF12889.7 RUS80997.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) EGF_MSP1_1 PF12946.7 RUS80997.1 - 0.24 11.5 7.9 0.73 9.9 7.9 1.9 1 0 0 1 1 1 0 MSP1 EGF domain 1 cEGF PF12662.7 RUS80997.1 - 0.71 9.9 8.4 0.31 11.0 0.7 3.3 3 1 0 3 3 3 0 Complement Clr-like EGF-like D_CNTX PF17492.2 RUS80997.1 - 8.2 6.7 13.4 1.1 9.5 7.9 2.4 2 0 0 2 2 2 0 Delta Ctenitoxins Plasmod_Pvs28 PF06247.11 RUS80997.1 - 8.6 6.8 13.2 0.26 11.6 6.7 1.9 2 0 0 2 2 2 0 Pvs28 EGF domain FXa_inhibition PF14670.6 RUS80997.1 - 9.4 6.6 11.8 2.8 8.3 4.8 2.8 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site 7tm_2 PF00002.24 RUS80998.1 - 2e-52 178.0 15.0 2.6e-52 177.6 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS80998.1 - 1.7e-15 57.1 5.0 1.7e-15 57.1 5.0 2.3 2 0 0 2 2 2 1 Hormone receptor domain DUF4064 PF13273.6 RUS80998.1 - 0.2 12.0 3.8 2.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Bax1-I PF01027.20 RUS80998.1 - 6.3 6.6 14.8 0.82 9.5 0.3 2.7 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Somatomedin_B PF01033.17 RUS80999.1 - 3.2e-07 30.6 16.0 3.2e-07 30.6 16.0 2.6 2 0 0 2 2 2 1 Somatomedin B domain Pro-rich_19 PF15455.6 RUS80999.1 - 0.032 13.4 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 Proline-rich 19 Homeodomain PF00046.29 RUS81000.1 - 4.2e-21 74.5 4.6 7.7e-21 73.7 4.6 1.5 1 0 0 1 1 1 1 Homeodomain Menin PF05053.13 RUS81000.1 - 0.0028 16.1 12.1 0.0034 15.8 12.1 1.1 1 0 0 1 1 1 1 Menin Macoilin PF09726.9 RUS81000.1 - 0.71 8.4 16.8 0.93 8.0 16.8 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 RUS81000.1 - 1.3 7.7 13.1 1.8 7.2 13.1 1.3 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 RUS81000.1 - 1.3 7.5 18.5 1.8 7.0 18.5 1.1 1 0 0 1 1 1 0 Utp14 protein ALMT PF11744.8 RUS81000.1 - 2.2 7.0 10.9 3.2 6.5 10.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5423 PF17461.2 RUS81000.1 - 2.5 6.9 5.3 5 5.9 5.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Zip PF02535.22 RUS81000.1 - 2.6 7.2 8.2 4.3 6.5 8.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 RUS81000.1 - 3.9 6.4 13.7 5.2 6.0 13.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Homeodomain PF00046.29 RUS81001.1 - 2.2e-21 75.4 5.2 3.3e-21 74.9 5.2 1.3 1 0 0 1 1 1 1 Homeodomain T-box PF00907.22 RUS81002.1 - 1.6e-64 217.6 0.4 2.2e-41 142.1 1.8 2.2 2 0 0 2 2 2 2 T-box Glyco_hydro_36C PF16874.5 RUS81002.1 - 0.0077 16.7 0.0 7.4 7.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 36 C-terminal domain Tam41_Mmp37 PF09139.11 RUS81003.1 - 3.7e-107 358.5 0.0 4.9e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Asparaginase_2 PF01112.18 RUS81004.1 - 3.2e-52 177.5 1.3 4.6e-52 176.9 1.3 1.2 1 0 0 1 1 1 1 Asparaginase Yae1_N PF09811.9 RUS81005.1 - 0.00033 20.3 11.0 0.00033 20.3 11.0 2.6 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Peptidase_S49 PF01343.18 RUS81005.1 - 1.3 9.0 17.6 0.45 10.5 0.4 4.3 4 0 0 4 4 4 0 Peptidase family S49 SPRY PF00622.28 RUS81006.1 - 2.9e-14 53.2 0.1 1.4e-06 28.5 0.0 3.2 3 0 0 3 3 3 2 SPRY domain gag-asp_proteas PF13975.6 RUS81007.1 - 0.058 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS81007.1 - 0.083 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF3530 PF12048.8 RUS81009.1 - 0.046 13.1 0.4 0.052 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) RVT_1 PF00078.27 RUS81011.1 - 6.2e-07 29.1 0.9 1.1e-06 28.4 0.2 1.8 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF615 PF04751.14 RUS81011.1 - 0.11 12.4 1.3 0.35 10.8 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF615) S-methyl_trans PF02574.16 RUS81012.1 - 8e-33 114.4 0.0 9.7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DEP PF00610.21 RUS81013.1 - 3e-14 52.8 0.2 2.3e-13 50.0 0.1 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribonucleas_3_3 PF14622.6 RUS81014.1 - 1.7e-06 28.2 0.0 3.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 RUS81014.1 - 0.1 13.2 0.1 1.7 9.3 0.1 2.4 1 1 0 1 1 1 0 Ribonuclease III domain Phosphodiest PF01663.22 RUS81015.1 - 3.7e-72 243.9 0.9 4.5e-72 243.6 0.9 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS81015.1 - 1.3e-06 28.1 0.0 0.00015 21.3 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 RUS81015.1 - 0.0023 17.3 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily PGP_phosphatase PF09419.10 RUS81015.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Exo_endo_phos PF03372.23 RUS81017.1 - 5.1e-14 52.4 0.0 6.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS81017.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase SHIPPO-rpt PF07004.12 RUS81018.1 - 9.2e-10 39.0 41.0 0.0002 22.1 0.5 6.8 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat DJ-1_PfpI PF01965.24 RUS81019.1 - 2.8e-50 170.3 0.2 3.4e-50 170.1 0.2 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 RUS81019.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain FHA PF00498.26 RUS81020.1 - 3.5e-17 62.5 0.0 1.2e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS81020.1 - 0.0007 19.9 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 RUS81021.1 - 6.8e-32 110.9 0.0 1.2e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81021.1 - 2.1e-16 60.0 0.0 3.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS81021.1 - 0.02 14.2 0.1 0.067 12.5 0.1 1.7 1 1 0 1 1 1 0 Kinase-like EF-hand_8 PF13833.6 RUS81022.1 - 0.00013 21.7 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS81022.1 - 0.0084 16.5 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair 7tm_1 PF00001.21 RUS81023.1 - 1.4e-05 24.6 10.3 1.4e-05 24.6 10.3 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 RUS81023.1 - 0.0054 15.9 6.8 0.0054 15.9 6.8 2.5 3 0 0 3 3 3 1 Taste receptor protein (TAS2R) DUF4064 PF13273.6 RUS81023.1 - 0.27 11.5 3.0 2 8.8 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) fn3 PF00041.21 RUS81024.1 - 1.9e-42 143.5 17.9 1.2e-09 38.4 0.1 7.2 7 0 0 7 7 7 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS81024.1 - 3.6e-15 56.3 15.4 0.022 15.3 0.0 7.3 6 1 0 6 6 6 5 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 RUS81024.1 - 0.00027 21.4 1.8 3.1 8.4 0.0 4.4 4 0 0 4 4 4 2 PhoD-like phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS81024.1 - 0.00053 20.3 5.7 2.9 8.3 0.0 5.2 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III SKG6 PF08693.10 RUS81024.1 - 0.0007 18.9 5.8 0.0012 18.2 5.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 RUS81024.1 - 0.0075 16.2 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 RUS81024.1 - 0.19 12.6 0.5 0.44 11.4 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 RUS81024.1 - 0.2 11.5 0.9 0.42 10.5 0.9 1.4 1 0 0 1 1 1 0 Rifin fn3 PF00041.21 RUS81026.1 - 9.5e-10 38.7 2.5 0.0004 20.7 0.2 2.3 2 0 0 2 2 2 2 Fibronectin type III domain SusE PF14292.6 RUS81026.1 - 0.017 15.4 0.2 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein TYW3 PF02676.14 RUS81027.1 - 6.2e-53 179.3 0.6 1.6e-52 178.0 0.6 1.6 1 1 0 1 1 1 1 Methyltransferase TYW3 KH_4 PF13083.6 RUS81027.1 - 0.026 14.4 0.0 0.093 12.6 0.0 1.8 2 0 0 2 2 2 0 KH domain Mtf2_C PF14061.6 RUS81028.1 - 4.5e-05 23.5 1.1 4.7 7.5 0.2 4.7 1 1 2 3 3 3 3 Polycomb-like MTF2 factor 2 Vwaint PF14624.6 RUS81028.1 - 0.00085 19.4 0.1 23 5.2 0.0 4.0 1 1 3 4 4 4 2 VWA / Hh protein intein-like YqbF PF14553.6 RUS81028.1 - 0.0086 15.9 0.2 55 3.7 0.0 4.1 1 1 3 5 5 5 0 YqbF, hypothetical protein domain SBD_N PF07005.11 RUS81028.1 - 0.24 11.1 0.1 11 5.7 0.1 2.8 1 1 0 1 1 1 0 Sugar-binding N-terminal domain Nucleos_tra2_C PF07662.13 RUS81030.1 - 3.5e-65 219.7 2.1 1.1e-64 218.1 2.1 1.9 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS81030.1 - 1.7e-22 79.8 0.4 1.7e-22 79.8 0.4 3.5 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS81030.1 - 1.3e-05 25.5 4.3 1.3e-05 25.5 4.3 2.9 3 0 0 3 3 3 1 Nucleoside recognition MAP65_ASE1 PF03999.12 RUS81031.1 - 1.8e-110 370.4 31.0 2.3e-110 370.1 31.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DNA_pack_N PF02500.15 RUS81031.1 - 0.21 11.4 3.5 0.11 12.4 0.6 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Baculo_PEP_C PF04513.12 RUS81031.1 - 0.8 9.7 2.5 35 4.4 0.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPH3 PF03000.14 RUS81032.1 - 5.6e-10 39.3 0.0 1.2e-08 35.0 0.0 2.5 1 1 0 1 1 1 1 NPH3 family BTB PF00651.31 RUS81032.1 - 1e-09 38.6 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain COX5A PF02284.16 RUS81032.1 - 0.0061 16.6 0.0 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va Flavodoxin_2 PF02525.17 RUS81032.1 - 0.026 14.2 0.0 0.47 10.1 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin-like fold CPSF100_C PF13299.6 RUS81032.1 - 0.095 12.9 0.2 0.095 12.9 0.2 2.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Pet20 PF08692.10 RUS81032.1 - 0.14 12.9 0.3 27 5.5 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Pex14_N PF04695.13 RUS81032.1 - 5.4 7.7 11.1 26 5.4 0.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_1 PF00515.28 RUS81035.1 - 1.1e-15 56.6 1.2 9.3e-07 28.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat FKBP_C PF00254.28 RUS81035.1 - 2.2e-14 53.5 0.0 5.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 RUS81035.1 - 5.3e-14 51.1 0.1 4.6e-06 26.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS81035.1 - 4.9e-11 41.9 1.3 2.2e-06 27.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS81035.1 - 2.1e-08 33.7 0.1 0.094 12.4 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 RUS81035.1 - 1.6e-06 28.5 0.1 0.018 15.8 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS81035.1 - 1.3e-05 24.9 0.0 0.026 14.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS81035.1 - 5.3e-05 23.6 3.3 0.0018 18.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS81035.1 - 0.00018 22.0 1.8 0.027 15.0 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS81035.1 - 0.00031 20.9 0.1 0.15 12.5 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81035.1 - 0.00038 21.0 0.3 0.44 11.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS81035.1 - 0.0016 18.7 0.6 0.069 13.5 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 RUS81035.1 - 0.0032 17.3 0.3 0.0098 15.7 0.1 1.9 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.6 RUS81035.1 - 0.088 13.1 0.0 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS81035.1 - 0.099 12.9 0.2 0.58 10.4 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5438 PF17506.2 RUS81036.1 - 0.084 13.2 1.2 0.99 9.8 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5438) ANAPC3 PF12895.7 RUS81037.1 - 0.76 10.0 4.7 1.2 9.4 0.8 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_25 PF13649.6 RUS81039.1 - 7.1e-13 49.1 0.0 2.7e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS81039.1 - 1.8e-12 47.7 0.0 3.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS81039.1 - 4e-10 39.4 0.0 5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS81039.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS81039.1 - 3.7e-07 30.8 0.0 1.8e-06 28.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS81039.1 - 5.4e-06 26.3 0.0 7.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 RUS81039.1 - 8.7e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 RUS81039.1 - 0.0006 19.7 0.0 0.065 13.1 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 RUS81039.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 RUS81039.1 - 0.022 14.3 0.2 0.048 13.2 0.2 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 RUS81039.1 - 0.047 13.3 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 RUS81039.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase cNMP_binding PF00027.29 RUS81041.1 - 1.5e-19 69.8 0.1 0.0015 18.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain HAD PF12710.7 RUS81041.1 - 0.079 13.3 0.0 0.32 11.4 0.0 2.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LMWPc PF01451.21 RUS81042.1 - 4.6e-24 85.4 0.0 5.7e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyco_transf_49 PF13896.6 RUS81043.1 - 2.4e-55 188.2 2.8 7.1e-44 150.5 1.1 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 RUS81043.1 - 3e-20 72.9 0.9 6.4e-20 71.8 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 RUS81043.1 - 2.4e-06 27.2 5.3 3.9e-06 26.5 5.3 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Pex16 PF08610.10 RUS81044.1 - 1.8e-78 264.0 0.0 2.1e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Ras PF00071.22 RUS81047.1 - 1.5e-30 105.9 0.0 2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81047.1 - 1.7e-12 47.6 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 RUS81048.1 - 5.9e-24 84.6 24.4 3.1e-23 82.3 24.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Presenilin PF01080.17 RUS81049.1 - 0.22 10.3 1.2 0.26 10.0 1.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4703 PF15775.5 RUS81050.1 - 0.18 11.6 4.6 0.36 10.6 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4703) DUF4569 PF15133.6 RUS81050.1 - 3.4 7.3 5.6 4.3 7.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CH PF00307.31 RUS81052.1 - 1e-15 57.9 0.0 2.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Androgen_recep PF02166.16 RUS81052.1 - 0.0049 15.8 1.1 0.0072 15.2 1.1 1.2 1 0 0 1 1 1 1 Androgen receptor CAMSAP_CH PF11971.8 RUS81052.1 - 0.024 14.5 0.0 0.074 12.9 0.0 1.9 1 1 0 1 1 1 0 CAMSAP CH domain CH_2 PF06294.11 RUS81052.1 - 0.057 13.5 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 CH-like domain in sperm protein BES1_N PF05687.13 RUS81053.1 - 3.7 7.9 13.0 16 5.9 13.0 2.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal HSP20 PF00011.21 RUS81054.1 - 2.7e-26 91.7 0.1 2.3e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Cupredoxin_1 PF13473.6 RUS81054.1 - 0.018 15.2 2.1 1.5 9.0 0.0 2.7 2 1 1 3 3 3 0 Cupredoxin-like domain Myosin_N PF02736.19 RUS81054.1 - 0.028 14.3 3.4 2.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain TFIIA PF03153.13 RUS81054.1 - 0.043 13.8 16.0 0.054 13.5 16.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulfate_transp PF00916.20 RUS81055.1 - 2.3e-90 303.1 18.9 2.9e-90 302.8 18.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RUS81055.1 - 4.5e-21 74.7 0.0 9e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain CH PF00307.31 RUS81056.1 - 1.4e-89 295.6 3.2 6.2e-23 81.1 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 RUS81056.1 - 2.4e-14 53.5 0.1 8.9e-14 51.7 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS81056.1 - 1.1e-13 49.9 0.9 1.6e-05 24.4 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RUS81056.1 - 5.4e-13 47.5 2.1 2.8e-05 23.4 0.6 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 RUS81056.1 - 4.1e-11 41.9 1.0 3.7e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS81056.1 - 3.7e-09 36.3 0.5 2e-08 33.9 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair CAMSAP_CH PF11971.8 RUS81056.1 - 3.3e-08 33.2 0.1 0.13 12.1 0.0 3.7 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_9 PF14658.6 RUS81056.1 - 0.0061 16.9 0.2 0.54 10.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain CH_2 PF06294.11 RUS81056.1 - 0.026 14.6 0.4 3.5 7.8 0.0 3.5 4 0 0 4 4 4 0 CH-like domain in sperm protein zf-LITAF-like PF10601.9 RUS81057.1 - 1.3e-23 83.0 11.5 1.7e-23 82.6 11.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.11 RUS81057.1 - 0.0017 17.8 1.8 0.008 15.7 0.2 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 RUS81057.1 - 0.04 14.1 4.0 0.082 13.1 0.9 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain DZR PF12773.7 RUS81057.1 - 0.07 13.2 5.1 0.81 9.8 5.4 2.1 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 RUS81057.1 - 0.089 12.8 1.6 0.12 12.4 1.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2321 PF10083.9 RUS81057.1 - 0.13 11.9 1.8 0.23 11.1 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rieske PF00355.26 RUS81058.1 - 4.3e-11 42.6 0.2 6.1e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 RUS81058.1 - 4.3e-09 36.2 0.0 5.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain OGFr_N PF04664.13 RUS81059.1 - 8.2e-65 218.2 3.8 1.2e-64 217.7 3.8 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region zf-C2H2 PF00096.26 RUS81061.1 - 3.5e-15 55.5 39.9 0.00062 20.1 1.2 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS81061.1 - 6.5e-14 51.4 36.6 8.9e-08 31.8 4.1 5.7 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS81061.1 - 2.1e-09 37.4 34.8 0.013 16.3 0.9 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS81061.1 - 1.2e-05 25.5 23.2 0.0045 17.4 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger double domain DUF629 PF04780.12 RUS81061.1 - 4.7e-05 22.1 4.1 0.82 8.1 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF629) zinc_ribbon_15 PF17032.5 RUS81061.1 - 0.00021 22.0 13.2 0.036 14.8 0.8 3.5 2 1 1 3 3 3 2 zinc-ribbon family zf-C2HC_2 PF13913.6 RUS81061.1 - 0.00024 20.9 4.0 0.52 10.3 0.3 3.1 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RUS81061.1 - 0.0005 20.3 29.9 0.017 15.4 1.1 5.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.7 RUS81061.1 - 0.003 17.7 6.1 11 6.2 0.3 3.9 3 0 0 3 3 3 0 Zinc-binding PyrI_C PF02748.15 RUS81061.1 - 0.0066 16.3 16.5 0.073 13.0 0.6 3.8 4 0 0 4 4 4 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 RUS81061.1 - 0.007 16.3 6.1 0.031 14.3 0.6 4.1 6 0 0 6 6 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS81061.1 - 0.015 15.6 17.3 0.98 9.8 1.1 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 RUS81061.1 - 0.02 15.0 6.9 0.098 12.8 0.6 3.4 2 0 0 2 2 2 0 Zinc-finger RNA_POL_M_15KD PF02150.16 RUS81061.1 - 0.22 11.4 1.0 31 4.5 0.1 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_3rep PF18868.1 RUS81061.1 - 0.3 11.8 5.8 3.4 8.3 2.5 3.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_Hakai PF18408.1 RUS81061.1 - 1.1 9.0 12.9 1.9 8.2 0.8 3.0 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain Rpr2 PF04032.16 RUS81061.1 - 1.2 9.5 10.6 14 6.1 0.8 3.5 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.15 RUS81061.1 - 2.3 8.3 25.8 1.1 9.3 0.3 4.3 4 1 1 5 5 4 0 BED zinc finger Thioredoxin_16 PF18569.1 RUS81064.1 - 0.1 12.7 0.1 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Flavi_M PF01004.19 RUS81065.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Rad10 PF03834.14 RUS81066.1 - 5.4e-50 168.2 0.1 8.2e-50 167.6 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 RUS81066.1 - 4.1e-05 24.1 0.0 9.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 RUS81066.1 - 5.9e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 RUS81066.1 - 0.005 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Ribosomal_L6 PF00347.23 RUS81067.1 - 7.2e-28 97.1 1.4 5e-16 59.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribo_biogen_C PF04034.13 RUS81069.1 - 6.5e-53 177.8 0.0 9.2e-53 177.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 RUS81069.1 - 2.1e-12 46.6 1.1 4.6e-12 45.6 1.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SCAPER_N PF16501.5 RUS81069.1 - 0.035 14.1 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Zip PF02535.22 RUS81069.1 - 0.73 9.0 3.4 0.43 9.7 0.4 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Pur_DNA_glyco PF02245.16 RUS81070.1 - 6.8e-63 211.3 0.0 8.7e-63 210.9 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Dus PF01207.17 RUS81071.1 - 1.5e-76 257.4 0.0 2.1e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 RUS81071.1 - 0.0026 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 RUS81071.1 - 0.0049 16.1 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 RUS81071.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 RUS81071.1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein SOR_SNZ PF01680.17 RUS81071.1 - 0.031 14.1 0.1 0.48 10.2 0.0 2.3 1 1 1 2 2 2 0 SOR/SNZ family DUF702 PF05142.12 RUS81071.1 - 0.056 13.9 2.8 0.12 12.8 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Ribosomal_S14 PF00253.21 RUS81071.1 - 0.26 11.1 4.0 0.74 9.6 4.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e TMC PF07810.13 RUS81072.1 - 1.1e-36 125.8 2.4 1.1e-36 125.8 2.4 2.2 2 0 0 2 2 2 1 TMC domain Ank_2 PF12796.7 RUS81073.1 - 2.1e-21 76.3 0.0 2.6e-10 40.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PLAT PF01477.23 RUS81073.1 - 6.7e-19 68.6 0.0 1.6e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Ank_4 PF13637.6 RUS81073.1 - 3.6e-18 65.7 0.7 2.3e-08 34.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS81073.1 - 5.2e-17 61.7 0.1 4.7e-08 33.1 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81073.1 - 5e-13 48.0 0.4 0.0028 18.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RUS81073.1 - 2.6e-12 46.6 0.8 0.00012 22.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.10 RUS81073.1 - 0.00097 19.6 1.7 0.4 11.2 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) Bul1_N PF04425.12 RUS81073.1 - 7 5.3 9.1 10 4.8 0.8 2.3 2 0 0 2 2 2 0 Bul1 N terminus Ank_2 PF12796.7 RUS81074.1 - 1.2e-14 54.6 0.0 6e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS81074.1 - 2.9e-13 50.0 0.1 8.6e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS81074.1 - 3.5e-08 33.5 0.1 9.5e-07 29.0 0.0 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81074.1 - 2.1e-06 27.6 0.0 0.043 14.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS81074.1 - 7.4e-06 26.2 0.0 0.053 14.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF2505 PF10698.9 RUS81075.1 - 3.9 7.6 8.4 2.5 8.2 2.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2505) DUF3914 PF13053.6 RUS81075.1 - 9.7 6.6 6.8 12 6.3 0.1 3.2 3 2 1 4 4 4 0 Protein of unknown function (DUF3914) 7tm_1 PF00001.21 RUS81076.1 - 5.4e-51 173.5 7.0 8.2e-51 172.8 7.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS81076.1 - 2.6e-11 43.4 7.6 5.1e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS81076.1 - 0.0027 17.0 2.9 0.0027 17.0 2.9 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS81076.1 - 0.0054 16.5 6.2 0.013 15.3 6.2 1.6 1 1 0 1 1 1 1 Olfactory receptor bZIP_1 PF00170.21 RUS81077.1 - 5.4e-06 26.4 14.8 1.3e-05 25.2 14.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS81077.1 - 1.2e-05 25.3 11.2 2.8e-05 24.1 11.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper ExsD PF16806.5 RUS81077.1 - 0.002 18.1 0.6 0.0043 17.0 0.6 1.5 1 0 0 1 1 1 1 Antiactivator protein ExsD CCDC85 PF10226.9 RUS81077.1 - 0.0033 17.1 5.9 0.0033 17.1 5.9 2.0 2 0 0 2 2 2 1 CCDC85 family NAM-associated PF14303.6 RUS81077.1 - 0.017 15.8 4.0 0.017 15.8 4.0 2.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 RUS81077.1 - 0.56 10.7 14.4 0.14 12.7 10.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor MAJIN PF15077.6 RUS81077.1 - 0.78 9.5 6.0 5.9 6.6 0.1 2.6 2 0 0 2 2 2 0 Membrane-anchored junction protein TMPIT PF07851.13 RUS81077.1 - 1.5 8.0 3.6 3.4 6.8 3.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein Ras PF00071.22 RUS81079.1 - 2.4e-59 199.5 0.1 3e-59 199.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81079.1 - 1.9e-34 118.4 0.1 3.2e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81079.1 - 2.4e-16 59.7 0.1 2.8e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS81079.1 - 1.1e-05 24.9 0.1 1.4e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS81079.1 - 0.00022 21.3 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS81079.1 - 0.00066 19.6 0.1 0.26 11.2 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 RUS81079.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 RUS81079.1 - 0.0099 15.4 0.2 0.042 13.4 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RUS81079.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 RUS81079.1 - 0.012 15.1 0.1 0.1 12.1 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 RUS81079.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS81079.1 - 0.044 14.1 0.1 0.27 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 RUS81079.1 - 0.049 12.9 0.2 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 Septin AAA_24 PF13479.6 RUS81079.1 - 0.051 13.3 0.3 0.081 12.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS81079.1 - 0.068 13.6 0.0 0.093 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 RUS81079.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS81079.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Chromo PF00385.24 RUS81080.1 - 6.2e-15 54.8 1.7 1.3e-14 53.8 1.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 RUS81080.1 - 6.5e-05 22.6 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Tudor-knot PF11717.8 RUS81080.1 - 0.00021 21.1 1.1 0.00029 20.7 0.3 1.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 RUS81080.1 - 0.047 13.9 0.3 0.076 13.2 0.3 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cwf_Cwc_15 PF04889.12 RUS81080.1 - 0.31 10.7 25.6 0.14 11.9 12.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein IRF PF00605.17 RUS81081.1 - 2.8e-29 101.5 0.0 6.1e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor DUF3094 PF11293.8 RUS81081.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Trypsin PF00089.26 RUS81082.1 - 7.9e-53 179.5 0.1 9.5e-53 179.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS81082.1 - 0.0035 18.3 0.0 0.0069 17.3 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain OCD_Mu_crystall PF02423.15 RUS81083.1 - 7.3e-84 281.4 1.2 8.2e-84 281.2 1.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 RUS81083.1 - 6.3e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 RUS81083.1 - 4.8e-05 23.9 0.0 0.00017 22.1 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 RUS81083.1 - 5.1e-05 24.1 0.1 0.00012 22.9 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 RUS81083.1 - 0.0059 16.8 1.0 0.015 15.5 0.3 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 RUS81083.1 - 0.011 16.1 0.1 0.039 14.4 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IlvN PF07991.12 RUS81083.1 - 0.042 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 RUS81083.1 - 0.062 12.6 0.4 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.23 RUS81083.1 - 0.069 13.1 0.2 0.21 11.6 0.2 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PI-PLC-X PF00388.19 RUS81084.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain MFS_1 PF07690.16 RUS81085.1 - 4.7e-28 98.1 41.8 2.6e-21 76.0 25.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS81085.1 - 3.8e-27 95.3 11.2 5.3e-27 94.8 11.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 RUS81086.1 - 4.1e-28 98.5 15.0 5.6e-28 98.0 15.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS81086.1 - 2.2e-23 82.8 50.5 9e-18 64.3 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 RUS81086.1 - 7.3 4.7 31.1 0.78 8.0 10.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) FAR1 PF03101.15 RUS81087.1 - 0.00062 20.4 0.1 0.0023 18.6 0.1 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain RBR PF17208.3 RUS81087.1 - 1.1 10.0 8.8 1.4 9.7 3.1 2.7 2 0 0 2 2 2 0 RNA binding Region AT_hook PF02178.19 RUS81087.1 - 1.3 9.1 10.8 1.4 9.1 8.8 2.2 1 1 0 1 1 1 0 AT hook motif FAR1 PF03101.15 RUS81088.1 - 2.4e-05 24.9 0.0 6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF5575 PF17738.1 RUS81088.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5575) AT_hook PF02178.19 RUS81088.1 - 3.6 7.8 10.4 3.9 7.7 8.7 2.1 2 0 0 2 2 2 0 AT hook motif Fez1 PF06818.15 RUS81089.1 - 9.2e-08 32.8 394.2 0.0034 17.9 17.0 20.4 2 2 17 19 19 19 12 Fez1 ATG16 PF08614.11 RUS81089.1 - 3.4e-07 30.7 448.8 0.01 16.1 17.5 22.0 1 1 20 21 21 21 11 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 RUS81089.1 - 0.00014 20.9 14.4 0.00014 20.9 14.4 13.1 1 1 12 14 14 14 2 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.6 RUS81089.1 - 0.00048 18.9 5.8 0.00048 18.9 5.8 13.8 1 1 13 14 14 14 9 AAA domain TMF_DNA_bd PF12329.8 RUS81089.1 - 0.00091 19.2 2.1 0.00091 19.2 2.1 35.7 11 7 28 40 40 40 9 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 RUS81089.1 - 0.00091 18.8 427.2 0.00093 18.7 19.2 19.3 1 1 19 20 20 20 8 Golgin subfamily A member 5 BRE1 PF08647.11 RUS81089.1 - 0.0018 18.3 4.2 0.0018 18.3 4.2 28.9 6 3 24 32 32 32 8 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 RUS81089.1 - 0.034 13.1 412.3 0.14 11.0 11.8 19.5 1 1 20 21 21 21 0 Spc7 kinetochore protein ERM PF00769.19 RUS81089.1 - 0.088 12.6 425.1 0.017 14.9 11.7 15.9 1 1 12 15 15 15 0 Ezrin/radixin/moesin family SPATA48 PF15073.6 RUS81090.1 - 4.9e-08 33.3 0.2 9.7e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 SIT PF15330.6 RUS81090.1 - 0.024 15.1 2.8 0.046 14.2 1.2 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4131 PF13567.6 RUS81090.1 - 2.4 7.8 5.6 1.7 8.2 3.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Spo12 PF05032.12 RUS81091.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Spo12 family GLEYA PF10528.9 RUS81091.1 - 0.11 13.0 0.3 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 GLEYA domain DUF3761 PF12587.8 RUS81092.1 - 0.1 13.1 53.5 5.7 7.4 1.1 9.9 2 1 7 9 9 9 0 Protein of unknown function (DUF3761) 7tm_1 PF00001.21 RUS81093.1 - 3.6e-14 52.7 6.5 3.6e-14 52.7 6.5 2.6 2 2 2 4 4 4 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS81093.1 - 0.0034 17.0 14.5 0.0034 17.0 14.5 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3980 PF13140.6 RUS81093.1 - 5.9 7.4 9.2 0.71 10.4 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) PRMT5_TIM PF17285.2 RUS81094.1 - 2.4e-72 243.2 0.1 3.2e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 RUS81094.1 - 5.9e-70 234.6 0.0 9.3e-70 234.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 RUS81094.1 - 9.3e-52 175.5 0.4 1.4e-51 174.8 0.4 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 RUS81094.1 - 0.0051 16.6 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 RUS81094.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N_2 PF13602.6 RUS81095.1 - 4.9e-14 53.5 0.1 2.1e-13 51.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS81095.1 - 2e-13 50.2 0.1 3.9e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS81095.1 - 8.1e-12 45.3 0.1 4e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PGAP1 PF07819.13 RUS81095.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Aldedh PF00171.22 RUS81096.1 - 3.3e-170 566.6 0.0 3.9e-170 566.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RUS81096.1 - 0.098 12.1 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ubiquitin PF00240.23 RUS81098.1 - 2.9e-23 81.4 0.0 4.9e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS81098.1 - 5.5e-09 35.7 0.0 8.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RUS81098.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain NUDIX_5 PF16705.5 RUS81098.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT ARPC4 PF05856.12 RUS81099.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Atg8 PF02991.16 RUS81100.1 - 4.5e-39 132.8 0.2 5.4e-39 132.6 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RUS81100.1 - 5.2e-07 30.0 0.1 8.2e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.8 RUS81100.1 - 0.015 15.1 0.4 1.2 9.1 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like NusB PF01029.18 RUS81100.1 - 0.07 13.4 0.2 0.13 12.5 0.2 1.6 1 1 0 1 1 1 0 NusB family TTL PF03133.15 RUS81101.1 - 1.2e-91 307.0 1.1 1.6e-91 306.5 1.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS81101.1 - 2.7e-09 36.7 0.0 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS81101.1 - 5e-05 22.7 0.0 0.00063 19.1 0.0 2.2 1 1 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 RUS81101.1 - 0.088 12.4 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain BROMI PF14961.6 RUS81102.1 - 0 1081.2 3.1 0 1081.1 3.1 1.0 1 0 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.18 RUS81102.1 - 0.025 14.2 1.2 0.054 13.1 1.2 1.6 1 0 0 1 1 1 0 Rab-GTPase-TBC domain BROMI PF14961.6 RUS81103.1 - 6.7e-19 66.9 0.5 7.2e-19 66.8 0.5 1.0 1 0 0 1 1 1 1 Broad-minded protein RII_binding_1 PF10522.9 RUS81103.1 - 0.65 10.4 2.8 1.9 8.9 0.2 2.6 3 0 0 3 3 3 0 RII binding domain Chordopox_G2 PF05796.12 RUS81104.1 - 0.032 13.7 0.7 0.067 12.6 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus protein G2 TPR_2 PF07719.17 RUS81104.1 - 0.066 13.3 3.3 16 5.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TcpA PF05946.12 RUS81104.1 - 0.19 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA UQ_con PF00179.26 RUS81105.1 - 7.8e-38 129.3 0.0 1.6e-37 128.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 RUS81105.1 - 3.3e-08 33.3 0.3 8.6e-08 32.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS81105.1 - 2.3e-07 30.5 0.3 5.3e-07 29.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RUS81105.1 - 0.0026 17.6 0.7 0.0046 16.8 0.7 1.4 1 0 0 1 1 1 1 F-box zf_C2H2_6 PF18450.1 RUS81105.1 - 0.11 12.2 0.7 0.73 9.6 0.1 2.4 2 0 0 2 2 2 0 Zinc Finger domain Aminotran_1_2 PF00155.21 RUS81106.1 - 4.3e-37 128.1 0.0 5.6e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS81106.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TRAPPC-Trs85 PF12739.7 RUS81108.1 - 2.9e-130 434.9 5.1 4.2e-130 434.4 5.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 RUS81108.1 - 0.075 13.2 0.1 10 6.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RUS81108.1 - 0.12 12.4 0.7 0.31 11.1 0.7 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat YajC PF02699.15 RUS81109.1 - 0.096 12.6 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit XPG_N PF00752.17 RUS81110.1 - 1.4e-35 121.8 0.0 2.8e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RUS81110.1 - 1.2e-31 108.9 0.0 3.8e-31 107.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 RUS81110.1 - 4.1e-07 30.5 0.1 3.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 RUS81110.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 RUS81110.1 - 0.017 15.7 0.0 0.045 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Adenylsucc_synt PF00709.21 RUS81110.1 - 0.06 12.3 0.4 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Adenylosuccinate synthetase HR1 PF02185.16 RUS81110.1 - 0.11 12.6 2.1 0.97 9.6 0.2 2.5 2 0 0 2 2 2 0 Hr1 repeat Metallophos_C PF14008.6 RUS81111.1 - 4.8e-15 56.2 0.1 1e-14 55.1 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RUS81111.1 - 4.4e-14 52.8 0.2 2.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 RUS81111.1 - 3e-08 34.4 0.0 5.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Protocadherin PF08374.11 RUS81111.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Protocadherin PhoD_N PF16655.5 RUS81111.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain EphA2_TM PF14575.6 RUS81111.1 - 0.077 13.9 0.0 0.3 12.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 RUS81111.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 RUS81111.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GAS2 PF02187.17 RUS81112.1 - 9.1e-20 70.5 0.1 1.6e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 RUS81112.1 - 6e-13 48.9 0.0 9.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_18 PF18354.1 RUS81113.1 - 0.0012 18.9 26.2 6.7 6.8 0.5 7.9 1 1 8 9 9 9 7 CarS bacterial SH3 domain DUF3432 PF11914.8 RUS81113.1 - 0.011 15.9 0.0 2.3 8.5 0.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3432) Speriolin_N PF15058.6 RUS81113.1 - 0.18 11.9 3.5 45 4.1 3.5 3.0 1 1 0 1 1 1 0 Speriolin N terminus BAR PF03114.18 RUS81113.1 - 0.34 10.5 0.3 54 3.3 0.0 3.8 2 1 2 4 4 4 0 BAR domain CorC_HlyC PF03471.17 RUS81114.1 - 0.015 15.3 31.3 20 5.3 0.1 11.2 1 1 9 10 10 10 0 Transporter associated domain NupH_GANP PF16768.5 RUS81115.1 - 2.2e-05 24.3 0.4 0.028 14.1 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin homology of Germinal-centre associated nuclear protein Collagen PF01391.18 RUS81115.1 - 0.00075 19.2 11.8 2.6 7.9 11.8 2.4 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) G-patch PF01585.23 RUS81116.1 - 1.1e-12 47.6 3.6 3.1e-12 46.2 3.6 1.8 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.7 RUS81116.1 - 2e-09 37.6 0.0 8.1e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 RUS81116.1 - 0.00054 20.6 0.0 0.0028 18.3 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif G-patch_2 PF12656.7 RUS81116.1 - 0.001 19.1 0.2 0.001 19.1 0.2 3.5 2 0 0 2 2 2 1 G-patch domain Nucleolin_bd PF16725.5 RUS81117.1 - 0.31 10.7 0.1 80 3.0 0.0 4.4 2 2 5 7 7 7 0 Nucleolin binding domain CTI PF06934.11 RUS81117.1 - 0.61 8.5 8.5 0.94 7.9 2.8 2.4 1 1 1 2 2 2 0 Fatty acid cis/trans isomerase (CTI) Cys_rich_CWC PF14375.6 RUS81118.1 - 0.0047 17.3 3.5 0.0047 17.3 3.5 2.9 3 0 0 3 3 3 1 Cysteine-rich CWC zf-H2C2_5 PF13909.6 RUS81118.1 - 0.053 13.3 9.5 2 8.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain IGF2_C PF08365.11 RUS81118.1 - 0.19 11.8 1.5 0.66 10.0 1.5 1.9 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Pkinase PF00069.25 RUS81120.1 - 7.3e-54 182.9 3.3 8.6e-54 182.7 0.2 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81120.1 - 4.2e-24 85.2 1.0 9.5e-23 80.8 1.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS81120.1 - 1.3e-06 28.0 0.4 0.0018 17.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 RUS81120.1 - 1.7e-05 24.0 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS81120.1 - 0.0011 19.0 0.5 0.011 15.7 0.4 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UBA PF00627.31 RUS81120.1 - 0.0039 17.1 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Pox_ser-thr_kin PF05445.11 RUS81120.1 - 0.007 15.4 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RUS81120.1 - 0.039 13.3 0.1 0.039 13.3 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3504 PF12012.8 RUS81123.1 - 5.1e-13 49.2 0.0 9.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) LAP2alpha PF11560.8 RUS81123.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha Pkinase PF00069.25 RUS81124.1 - 6.6e-55 186.3 0.2 1.4e-54 185.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81124.1 - 2.6e-25 89.2 0.0 7.1e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS81124.1 - 0.063 12.6 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like SUIM_assoc PF16619.5 RUS81124.1 - 5.5 7.1 17.5 0.028 14.5 5.3 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2160 PF09928.9 RUS81125.1 - 0.47 10.8 3.4 5.7 7.3 0.5 2.4 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2160) Gemini_AL1 PF00799.20 RUS81125.1 - 0.92 9.9 3.9 9.1 6.7 0.1 2.9 1 1 2 3 3 3 0 Geminivirus Rep catalytic domain DUF2626 PF11117.8 RUS81125.1 - 1.6 9.5 20.0 11 6.8 2.9 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2626) Fijivirus_P9-2 PF06837.11 RUS81125.1 - 6.4 6.2 10.2 7.4 6.0 10.2 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein 7tm_1 PF00001.21 RUS81128.1 - 7e-09 35.4 25.1 9.6e-09 34.9 25.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Complex1_LYR PF05347.15 RUS81129.1 - 6.8e-06 26.0 0.4 1.2e-05 25.3 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS81129.1 - 0.018 15.8 0.4 0.023 15.4 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DDE_Tnp_1_2 PF13586.6 RUS81129.1 - 0.071 13.5 0.3 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 Transposase DDE domain Spore_II_R PF09551.10 RUS81129.1 - 0.12 12.8 0.6 0.15 12.5 0.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Morc6_S5 PF17942.1 RUS81130.1 - 3e-40 137.5 0.1 6.8e-40 136.3 0.1 1.6 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 RUS81130.1 - 2.5e-16 59.4 5.3 2.5e-16 59.4 5.3 2.4 2 0 0 2 2 2 1 CW-type Zinc Finger HATPase_c_3 PF13589.6 RUS81130.1 - 6.4e-14 51.9 0.2 6.3e-13 48.7 0.0 2.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF927 PF06048.11 RUS81130.1 - 0.52 9.8 4.8 2.2 7.8 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF927) GFO_IDH_MocA PF01408.22 RUS81131.1 - 3.4e-18 66.6 0.0 6.7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Biliv-reduc_cat PF09166.10 RUS81131.1 - 7.7e-06 26.2 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Biliverdin reductase, catalytic NAD_binding_3 PF03447.16 RUS81131.1 - 6.9e-05 23.5 0.3 0.00013 22.6 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Arc_PepC PF06819.11 RUS81131.1 - 0.0033 17.6 0.2 0.0072 16.4 0.2 1.6 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain Pkinase PF00069.25 RUS81132.1 - 2.1e-70 237.1 0.0 2.9e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81132.1 - 7.6e-44 149.9 0.0 1.3e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS81132.1 - 3.8e-07 29.7 0.0 7.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS81132.1 - 7.1e-05 22.3 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS81132.1 - 7.9e-05 21.8 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS81132.1 - 0.00058 18.8 0.7 0.0011 17.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RUS81132.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 RUS81132.1 - 0.16 11.5 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2798 PF11391.8 RUS81136.1 - 2.6e-05 24.1 87.7 1.8e+04 -54.1 87.7 6.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RUS81136.1 - 0.0053 16.7 21.5 0.51 10.4 3.8 4.3 2 1 0 2 2 2 1 Glycine zipper Romo1 PF10247.9 RUS81136.1 - 0.05 14.0 22.7 3.5 8.0 1.9 5.4 2 2 3 5 5 5 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.6 RUS81136.1 - 4.9 7.0 9.0 9.8 6.0 0.4 3.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper GMC_oxred_N PF00732.19 RUS81137.1 - 2.5e-76 256.9 0.0 3.2e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RUS81137.1 - 2.2e-36 125.6 0.0 7.5e-36 123.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RUS81137.1 - 1.1e-07 31.4 0.0 0.0083 15.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 RUS81137.1 - 1.8e-06 27.4 0.0 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS81137.1 - 6.7e-05 23.0 0.2 0.00015 21.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS81137.1 - 7.6e-05 22.4 0.2 0.0071 16.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 RUS81137.1 - 8.3e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 RUS81137.1 - 0.023 13.4 0.1 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 RUS81137.1 - 0.039 13.1 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 RUS81137.1 - 0.043 14.4 1.1 2.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS81137.1 - 0.059 12.6 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS81137.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 RUS81137.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sua5_yciO_yrdC PF01300.18 RUS81138.1 - 1.1e-43 148.9 0.0 1.4e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Lectin_C PF00059.21 RUS81139.1 - 7.6e-06 26.6 0.0 1.9e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain Med9 PF07544.13 RUS81139.1 - 0.00055 20.0 1.7 0.0075 16.3 0.1 2.5 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 zf-CRD PF17979.1 RUS81142.1 - 0.82 9.8 11.0 2.3 8.3 1.8 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions UPF0193 PF05250.11 RUS81142.1 - 2.6 7.8 11.6 6.6 6.5 4.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0193) Sre PF03125.18 RUS81142.1 - 7.8 5.5 6.3 5.6 6.0 0.5 2.1 1 1 1 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor Sulfate_transp PF00916.20 RUS81144.1 - 7.1e-104 347.6 22.9 8.6e-104 347.3 22.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RUS81144.1 - 8.5e-20 70.5 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain OATP PF03137.20 RUS81146.1 - 3.6e-16 58.6 5.5 1.4e-15 56.6 5.5 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SEEEED PF14797.6 RUS81146.1 - 0.12 12.5 5.9 0.32 11.2 5.9 1.6 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex OATP PF03137.20 RUS81147.1 - 3.3e-15 55.4 2.9 3.6e-15 55.3 2.9 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kazal_2 PF07648.15 RUS81147.1 - 1.5e-05 25.0 5.3 2.7e-05 24.2 5.3 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS81147.1 - 0.016 15.2 3.4 0.027 14.5 3.4 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain SOUL PF04832.12 RUS81148.1 - 1.9e-45 155.1 0.0 2.6e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein Ion_trans PF00520.31 RUS81149.1 - 7.2e-18 64.7 5.4 8.2e-18 64.5 5.4 1.1 1 0 0 1 1 1 1 Ion transport protein PsaD PF02531.16 RUS81149.1 - 0.0032 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 PsaD PQ-loop PF04193.14 RUS81150.1 - 1.1e-19 70.0 11.0 1.3e-11 44.1 0.5 3.4 3 1 0 3 3 3 2 PQ loop repeat Cyd_oper_YbgE PF09600.10 RUS81150.1 - 0.23 11.8 4.6 0.57 10.6 1.1 3.1 2 1 1 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) SRTM1 PF15872.5 RUS81150.1 - 1.7 8.8 8.3 2.6 8.2 3.5 2.5 1 1 1 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Sulfotransfer_1 PF00685.27 RUS81151.1 - 3.1e-71 240.0 0.3 3.6e-71 239.8 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS81151.1 - 0.00048 20.6 0.0 0.074 13.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Ras PF00071.22 RUS81152.1 - 1.3e-53 180.9 0.0 1.5e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81152.1 - 6.1e-22 78.1 0.0 9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81152.1 - 6.6e-09 35.4 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SPRY PF00622.28 RUS81153.1 - 4.6e-20 71.9 0.0 6.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 RUS81153.1 - 7.8e-09 35.3 1.7 1.6e-08 34.3 1.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS81153.1 - 4.8e-08 32.7 1.9 4.8e-08 32.7 1.9 2.1 3 0 0 3 3 3 1 F-box domain F-box_5 PF18511.1 RUS81153.1 - 0.0004 19.9 0.4 0.00075 19.0 0.4 1.4 1 0 0 1 1 1 1 F-box Exonuc_X-T_C PF08411.10 RUS81153.1 - 0.077 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal PRMT5_C PF17286.2 RUS81154.1 - 0.0065 16.4 0.1 2.1 8.2 0.0 2.3 2 1 0 2 2 2 2 PRMT5 oligomerisation domain Peptidase_M3 PF01432.20 RUS81155.1 - 3.8e-86 290.2 0.3 4.3e-86 290.0 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M3 AgI_II_C2 PF17998.1 RUS81155.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Cell surface antigen I/II C2 terminal domain JAB PF01398.21 RUS81156.1 - 4.1e-22 78.4 1.0 8.6e-22 77.3 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RUS81156.1 - 1.3e-19 70.7 0.1 2.1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function CENP-N PF05238.13 RUS81157.1 - 9.4e-05 21.9 1.1 0.001 18.5 1.1 2.1 1 1 0 1 1 1 1 Kinetochore protein CHL4 like G-7-MTase PF12803.7 RUS81157.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Septin PF00735.18 RUS81158.1 - 7.5e-123 409.3 0.0 7.5e-123 409.3 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 RUS81158.1 - 3.9e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS81158.1 - 3.7e-06 27.0 3.4 6.7e-05 22.9 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 RUS81158.1 - 0.00099 18.5 0.0 0.00099 18.5 0.0 1.9 2 0 0 2 2 1 1 AIG1 family Ras PF00071.22 RUS81158.1 - 0.003 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 RUS81158.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 RUS81158.1 - 0.007 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS81158.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 RUS81158.1 - 0.044 14.3 3.4 0.071 13.6 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 RUS81158.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RUS81158.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 RUS81158.1 - 0.072 12.6 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 RUS81158.1 - 0.17 11.4 7.1 2.2 7.8 0.1 3.8 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.15 RUS81158.1 - 0.47 10.0 7.0 0.88 9.1 7.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gtr1_RagA PF04670.12 RUS81158.1 - 0.56 9.5 0.0 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 RUS81158.1 - 0.61 10.1 11.3 1.6 8.8 0.3 3.6 2 1 0 3 3 3 0 Dynamin family Strep_SA_rep PF06696.11 RUS81158.1 - 2.3 8.3 7.3 0.28 11.2 0.5 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 RUS81158.1 - 2.4 8.2 7.1 66 3.5 5.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain CARD_2 PF16739.5 RUS81159.1 - 1.6e-18 66.5 1.0 9.4e-10 38.4 0.5 2.4 2 0 0 2 2 2 2 Caspase recruitment domain CARD PF00619.21 RUS81159.1 - 8.5e-09 35.3 1.6 1.2e-06 28.4 0.6 2.6 2 0 0 2 2 2 2 Caspase recruitment domain YaaC PF14175.6 RUS81159.1 - 0.0077 15.5 5.0 0.058 12.6 0.2 2.5 1 1 1 3 3 3 2 YaaC-like Protein DUF1359 PF07097.11 RUS81159.1 - 0.014 15.6 2.9 3.2 8.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) MucBP_2 PF17965.1 RUS81159.1 - 0.055 14.1 0.1 2.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Mucin binding domain MBOAT PF03062.19 RUS81160.1 - 8e-34 117.5 13.4 1.1e-33 117.0 13.4 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RUS81160.1 - 0.00088 19.5 2.3 0.0023 18.2 2.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ThiF PF00899.21 RUS81161.1 - 4.4e-74 248.9 0.1 1.4e-73 247.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 RUS81161.1 - 1e-22 80.5 1.8 2.2e-22 79.4 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 RUS81161.1 - 2.6e-08 34.1 0.0 0.0047 16.9 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 RUS81161.1 - 0.0018 18.7 0.1 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 RUS81161.1 - 0.0095 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UBA2_C PF16195.5 RUS81161.1 - 0.094 13.4 5.8 0.26 12.0 5.8 1.7 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Phage_holin_5_2 PF16079.5 RUS81161.1 - 0.22 11.9 1.1 0.43 10.9 1.1 1.4 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V IMPDH PF00478.25 RUS81162.1 - 6e-85 285.3 0.5 8.5e-85 284.8 0.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 RUS81162.1 - 0.00035 19.7 0.6 0.00061 18.9 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase dCache_3 PF14827.6 RUS81162.1 - 0.0053 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Double sensory domain of two-component sensor kinase Aldolase PF01081.19 RUS81162.1 - 0.033 13.6 0.1 0.19 11.1 0.0 2.1 1 1 1 2 2 2 0 KDPG and KHG aldolase Thioredoxin PF00085.20 RUS81163.1 - 2.5e-25 88.4 0.0 1.8e-23 82.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 RUS81163.1 - 1.1e-12 48.2 0.0 5.5e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain TraF PF13728.6 RUS81163.1 - 2.2e-05 24.4 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 RUS81163.1 - 2.7e-05 24.6 0.1 0.00066 20.1 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS81163.1 - 0.00026 21.2 0.0 4 7.8 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 RUS81163.1 - 0.0032 16.9 0.0 0.016 14.6 0.0 2.0 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RUS81163.1 - 0.004 17.1 0.2 2.8 7.9 0.1 3.3 2 1 1 3 3 3 1 AhpC/TSA family Redoxin PF08534.10 RUS81163.1 - 0.026 14.2 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Redoxin HyaE PF07449.11 RUS81163.1 - 0.058 13.4 0.0 6 6.9 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 RUS81163.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Fibrinogen_C PF00147.18 RUS81164.1 - 7e-65 218.9 7.1 9.6e-65 218.5 7.1 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF445 PF04286.12 RUS81164.1 - 0.07 12.9 0.3 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PVL_ORF50 PF07768.11 RUS81164.1 - 0.12 12.7 1.1 0.31 11.3 1.1 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family Ras PF00071.22 RUS81166.1 - 2.4e-32 111.8 0.0 2.7e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81166.1 - 3.8e-21 75.5 0.0 4.9e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81166.1 - 2e-08 33.9 0.0 7.2e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS81166.1 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 RUS81166.1 - 0.00028 20.2 0.0 0.024 13.8 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RUS81166.1 - 0.00031 20.2 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RUS81166.1 - 0.00062 19.2 0.0 0.00073 19.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS81166.1 - 0.058 13.3 0.0 7.9 6.4 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 RUS81166.1 - 0.089 12.3 0.0 0.58 9.7 0.0 2.0 1 1 0 2 2 2 0 P-loop containing dynein motor region Rubella_E2 PF05749.11 RUS81166.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 PduV-EutP PF10662.9 RUS81166.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 RUS81167.1 - 6.1e-16 58.4 0.0 6.3e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81167.1 - 1.3e-07 31.9 0.0 1.6e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81167.1 - 0.0037 16.7 0.0 0.0094 15.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family IBR PF01485.21 RUS81168.1 - 6.3e-06 26.3 22.8 7.1e-05 23.0 4.3 5.0 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RUS81168.1 - 1.2e-05 25.5 5.6 1.2e-05 25.5 5.6 5.4 6 1 1 7 7 7 1 Ring finger domain zf-C3HC4 PF00097.25 RUS81168.1 - 4.5e-05 23.2 4.9 4.5e-05 23.2 4.9 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 RUS81168.1 - 8.9e-05 22.2 0.1 0.00024 20.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family zf-C3HC4_2 PF13923.6 RUS81168.1 - 0.00011 21.9 5.8 0.00011 21.9 5.8 5.2 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS81168.1 - 0.00039 20.4 5.2 0.00039 20.4 5.2 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 RUS81168.1 - 0.00078 19.1 4.2 0.00078 19.1 4.2 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RanBP PF00641.18 RUS81168.1 - 0.00079 18.7 1.1 0.00079 18.7 1.1 4.6 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others zf-RING_5 PF14634.6 RUS81168.1 - 0.0012 18.8 6.1 0.0012 18.8 6.1 5.2 5 2 0 6 6 6 1 zinc-RING finger domain Somatomedin_B PF01033.17 RUS81169.1 - 4.7e-09 36.5 11.8 1.6e-08 34.8 11.8 2.0 1 0 0 1 1 1 1 Somatomedin B domain DUF4834 PF16118.5 RUS81170.1 - 0.0095 16.9 5.4 0.035 15.1 4.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF983 PF06170.12 RUS81170.1 - 0.091 13.2 0.5 2.6 8.5 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF3139 PF11337.8 RUS81170.1 - 0.62 10.7 5.7 1.3 9.7 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Tmemb_9 PF05434.11 RUS81170.1 - 0.92 9.4 3.9 1.5 8.7 3.9 1.3 1 0 0 1 1 1 0 TMEM9 EphA2_TM PF14575.6 RUS81170.1 - 1.1 10.2 3.7 2.7 8.9 3.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain vMSA PF00695.19 RUS81170.1 - 1.3 8.0 5.4 1.8 7.6 5.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Baculo_11_kDa PF06143.11 RUS81170.1 - 1.5 8.5 7.6 3.2 7.4 7.6 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4446 PF14584.6 RUS81170.1 - 2.3 8.2 5.1 4 7.4 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HLH PF00010.26 RUS81173.1 - 1.9e-15 56.5 0.8 8.6e-15 54.4 0.8 2.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA_11 PF13086.6 RUS81173.1 - 0.11 12.3 6.2 0.056 13.2 3.0 1.9 2 0 0 2 2 2 0 AAA domain UPA_2 PF17809.1 RUS81174.1 - 0.038 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 UPA domain Dimer_Tnp_hAT PF05699.14 RUS81175.1 - 3e-07 30.1 0.1 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 RUS81176.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Fae PF08714.11 RUS81176.1 - 0.18 11.8 0.0 46 3.9 0.0 3.2 3 0 0 3 3 3 0 Formaldehyde-activating enzyme (Fae) DUF4209 PF13910.6 RUS81177.1 - 1.4e-15 57.3 0.0 3.8e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4209) CRISPR_Cas2 PF09827.9 RUS81177.1 - 0.0026 17.9 0.2 3.2 8.0 0.0 2.5 2 0 0 2 2 2 2 CRISPR associated protein Cas2 CorA PF01544.18 RUS81177.1 - 0.074 12.3 0.3 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SMK-1 PF04802.15 RUS81179.1 - 5.4e-78 261.2 4.8 1.5e-77 259.7 4.8 1.8 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 RUS81179.1 - 0.0023 18.2 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RUS81179.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Nebulin PF00880.18 RUS81179.1 - 0.17 11.8 2.0 6.3 6.8 0.3 2.6 2 0 0 2 2 2 0 Nebulin repeat Atg14 PF10186.9 RUS81180.1 - 2.2e-25 89.4 11.0 8.5e-24 84.2 11.0 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_C50 PF03568.17 RUS81180.1 - 0.02 14.0 4.3 0.029 13.5 4.3 1.1 1 0 0 1 1 1 0 Peptidase family C50 Paralemmin PF03285.15 RUS81180.1 - 3.7 7.0 8.7 12 5.3 8.7 1.8 1 1 0 1 1 1 0 Paralemmin TSP_1 PF00090.19 RUS81182.1 - 1.4e-11 44.4 10.2 2.3e-08 34.1 1.9 2.9 3 0 0 3 3 3 2 Thrombospondin type 1 domain TSP_1 PF00090.19 RUS81183.1 - 7.6e-29 99.7 43.7 1.9e-12 47.2 7.9 4.4 4 0 0 4 4 4 3 Thrombospondin type 1 domain Laminin_G_1 PF00054.23 RUS81183.1 - 8.1e-18 64.9 0.0 1.2e-11 45.0 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 RUS81183.1 - 1.2e-14 55.0 0.2 1.9e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain CD36 PF01130.21 RUS81184.1 - 1.8e-36 125.7 0.0 5.4e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 CD36 family zf-C3HC4_3 PF13920.6 RUS81184.1 - 0.2 11.6 1.8 2 8.3 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS81184.1 - 0.32 10.9 3.7 1.5 8.8 0.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 AlbA_2 PF04326.14 RUS81185.1 - 1.7e-12 47.7 0.0 4.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding domain AlbA_2 PF04326.14 RUS81186.1 - 1.4e-21 77.1 0.1 1.7e-20 73.5 0.0 2.5 2 1 0 2 2 2 1 Putative DNA-binding domain AFT PF08731.11 RUS81186.1 - 0.29 11.5 5.4 1.9 8.9 5.4 2.2 1 1 0 1 1 1 0 Transcription factor AFT EF-hand_1 PF00036.32 RUS81187.1 - 2.5e-24 83.0 9.1 1.4e-08 33.7 0.1 4.6 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 RUS81187.1 - 5.6e-23 78.9 5.5 4e-08 32.6 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RUS81187.1 - 1.3e-22 80.0 3.3 1.8e-13 50.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS81187.1 - 5.7e-17 61.3 11.9 1.7e-10 40.6 0.2 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RUS81187.1 - 3.8e-12 45.1 1.8 4.2e-06 26.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RUS81187.1 - 2.1e-06 27.9 0.1 0.086 13.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 RUS81187.1 - 0.0017 18.4 0.2 0.0076 16.3 0.0 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 RUS81187.1 - 0.0025 17.8 0.6 0.33 10.9 0.0 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 RUS81187.1 - 0.0037 17.2 0.2 0.48 10.4 0.0 2.6 1 1 2 3 3 3 1 Tellurite resistance protein TerB MotA_activ PF09114.10 RUS81187.1 - 0.0063 16.6 0.2 1.2 9.3 0.0 2.2 1 1 0 2 2 2 1 Transcription factor MotA, activation domain Caleosin PF05042.13 RUS81187.1 - 0.0064 16.4 0.3 0.81 9.6 0.1 2.6 1 1 1 2 2 2 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 RUS81187.1 - 0.01 16.2 0.0 0.075 13.4 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RUS81187.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 RUS81187.1 - 0.043 14.0 0.5 2.9 8.2 0.1 2.9 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_11 PF08976.11 RUS81187.1 - 0.072 14.0 0.0 0.27 12.1 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain Cystatin PF00031.21 RUS81188.1 - 3.4e-05 24.0 0.2 0.00035 20.8 0.0 2.4 2 1 0 2 2 2 1 Cystatin domain SQAPI PF16845.5 RUS81188.1 - 0.00015 22.1 0.1 0.00027 21.2 0.1 1.4 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor HrpB1_HrpK PF09613.10 RUS81188.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) NOB1_Zn_bind PF08772.11 RUS81189.1 - 0.0068 16.5 0.3 0.0092 16.1 0.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like S1 PF00575.23 RUS81191.1 - 4.5e-18 65.3 0.1 9.2e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 RUS81191.1 - 1.9e-14 53.8 0.0 3.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 RUS81191.1 - 8.6e-05 22.8 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 HMG_box PF00505.19 RUS81192.1 - 1e-11 45.1 0.5 3.3e-11 43.4 0.5 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HLH PF00010.26 RUS81192.1 - 4e-05 23.5 0.2 8.5e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HMG_box_2 PF09011.10 RUS81192.1 - 6.6e-05 23.4 2.4 0.00012 22.6 0.5 2.4 2 0 0 2 2 2 1 HMG-box domain zf-C2H2_jaz PF12171.8 RUS81193.1 - 0.00011 22.4 0.1 0.00024 21.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3813 PF12758.7 RUS81193.1 - 0.045 14.1 0.4 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) DUF4646 PF15496.6 RUS81193.1 - 0.14 12.8 1.2 0.24 12.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4646) DUF1189 PF06691.11 RUS81193.1 - 6.5 6.3 5.1 9.4 5.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Cu-oxidase_3 PF07732.15 RUS81194.1 - 1e-36 125.6 0.2 2.1e-35 121.3 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RUS81194.1 - 4.8e-30 104.1 2.2 1.6e-26 92.7 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 RUS81194.1 - 1.9e-26 93.1 0.0 1e-25 90.7 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Methyltransf_21 PF05050.12 RUS81195.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase FkbM domain Ribosomal_S10 PF00338.22 RUS81196.1 - 3.4e-24 84.9 0.2 5.3e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FAD_binding_7 PF03441.14 RUS81197.1 - 8.4e-59 198.4 0.8 1.3e-58 197.8 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RUS81197.1 - 6.6e-32 110.8 0.0 1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Exo70 PF03081.15 RUS81197.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Exo70 exocyst complex subunit WD40 PF00400.32 RUS81199.1 - 1.5e-17 63.6 18.6 0.00022 22.0 0.5 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS81199.1 - 5.3e-11 42.7 2.9 0.0002 21.6 0.0 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain MIP PF00230.20 RUS81201.1 - 1.3e-43 149.3 9.5 1.7e-43 149.0 9.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 RUS81203.1 - 9.3e-27 94.0 17.6 1.3e-26 93.5 17.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS81203.1 - 3.6e-17 62.3 47.2 1.1e-16 60.7 36.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sortilin-Vps10 PF15902.5 RUS81204.1 - 4.3e-72 243.3 0.3 1e-71 242.1 0.3 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 RUS81204.1 - 3.4e-31 108.9 10.2 6e-31 108.1 10.2 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 RUS81204.1 - 4.3e-20 71.3 1.5 8.8e-09 35.1 0.4 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 RUS81204.1 - 1.1e-07 30.8 6.9 0.22 11.7 0.4 5.2 4 0 0 4 4 4 2 BNR/Asp-box repeat DUF4448 PF14610.6 RUS81204.1 - 0.017 14.9 1.6 0.053 13.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 RUS81204.1 - 0.022 14.7 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family PKD_3 PF16820.5 RUS81204.1 - 0.039 13.7 0.2 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 PKD-like domain He_PIG PF05345.12 RUS81204.1 - 0.072 13.3 1.2 1.1 9.5 0.2 2.9 3 0 0 3 3 3 0 Putative Ig domain SKG6 PF08693.10 RUS81204.1 - 1.8 8.1 11.0 3.2 7.2 11.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BNR_6 PF15899.5 RUS81204.1 - 2.1 8.7 4.5 14 6.0 0.0 4.3 5 0 0 5 5 5 0 BNR-Asp box repeat Ribosomal_S17e PF00833.18 RUS81205.1 - 4.2e-25 88.0 3.7 7.9e-16 58.1 1.7 2.0 1 1 1 2 2 2 2 Ribosomal S17 DUF3219 PF11514.8 RUS81205.1 - 0.014 15.4 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Glyoxalase_4 PF13669.6 RUS81206.1 - 4.8e-09 36.4 0.0 0.00064 20.0 0.0 3.0 3 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 RUS81206.1 - 1.1e-08 35.3 0.0 5e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 RUS81206.1 - 1.3e-05 25.4 0.0 0.11 12.6 0.0 2.8 2 1 1 3 3 3 2 Glyoxalase-like domain Flavoprotein PF02441.19 RUS81207.1 - 1.9e-46 157.7 0.0 2.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Ig_3 PF13927.6 RUS81208.1 - 1.5e-22 80.0 0.1 8.6e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS81208.1 - 1.5e-21 76.2 0.2 6.8e-13 48.5 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RUS81208.1 - 2e-16 60.1 0.7 7.6e-12 45.4 0.2 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 RUS81208.1 - 2.5e-16 59.6 0.4 9.7e-08 32.1 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS81208.1 - 1.5e-11 44.4 0.3 8.1e-05 22.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS81208.1 - 8.2e-08 31.7 0.0 0.0096 15.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 RUS81208.1 - 2.7e-05 24.5 0.6 1.1 9.8 0.4 4.1 2 2 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 RUS81208.1 - 0.023 14.8 0.2 0.39 10.8 0.1 2.5 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 RUS81208.1 - 0.064 12.0 0.1 0.23 10.1 0.1 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E GW PF13457.6 RUS81208.1 - 0.13 12.9 1.0 0.83 10.3 1.1 2.2 1 1 1 2 2 2 0 GW (Gly-Tryp) dipeptide domain zf_CCCH_4 PF18345.1 RUS81209.1 - 2.6e-07 30.5 4.3 5.1e-07 29.5 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 RUS81209.1 - 3.9e-07 29.7 1.3 7e-07 28.9 1.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 RUS81209.1 - 4.4e-05 23.3 0.6 6.7e-05 22.7 0.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 RUS81209.1 - 0.025 14.8 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 RUS81209.1 - 0.31 11.6 3.7 0.56 10.8 3.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 RUS81210.1 - 1.7e-08 35.2 101.9 0.02 15.7 23.9 5.5 1 1 3 4 4 4 3 Nucleoporin FG repeat region BK_channel_a PF03493.18 RUS81211.1 - 1.3e-24 86.2 0.1 2.5e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RUS81211.1 - 3.4e-11 43.0 1.4 7.1e-11 41.9 1.4 1.5 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 RUS81211.1 - 0.0088 16.3 0.1 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain Ion_trans PF00520.31 RUS81211.1 - 0.23 10.6 4.5 0.4 9.9 4.5 1.3 1 0 0 1 1 1 0 Ion transport protein DUF5522 PF17653.1 RUS81211.1 - 2.6 8.1 5.5 5.7 7.0 5.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) DUF2070 PF09843.9 RUS81212.1 - 0.5 8.6 4.1 0.61 8.3 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MAM PF00629.23 RUS81213.1 - 9e-06 25.7 1.8 0.00012 22.1 0.0 2.4 2 1 0 2 2 2 1 MAM domain, meprin/A5/mu Usher_TcfC PF17271.2 RUS81213.1 - 0.12 11.2 0.2 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 TcfC Usher-like barrel domain Amnionless PF14828.6 RUS81214.1 - 0.0056 15.6 0.0 0.0071 15.2 0.0 1.1 1 0 0 1 1 1 1 Amnionless Insulin_TMD PF17870.1 RUS81214.1 - 0.012 15.6 0.4 0.022 14.8 0.4 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Podoplanin PF05808.11 RUS81214.1 - 0.016 15.3 9.0 0.22 11.6 9.0 2.1 1 1 0 1 1 1 0 Podoplanin Syndecan PF01034.20 RUS81214.1 - 0.054 13.4 1.1 0.087 12.7 1.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF347 PF03988.12 RUS81214.1 - 0.056 13.6 0.3 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) PTP_tm PF18861.1 RUS81214.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 RUS81214.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SOG2 PF10428.9 RUS81214.1 - 0.22 10.7 13.3 0.33 10.1 13.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM154 PF15102.6 RUS81214.1 - 2.5 8.0 10.6 1.4e+02 2.4 10.3 2.6 1 1 0 1 1 1 0 TMEM154 protein family Hamartin PF04388.12 RUS81214.1 - 6.9 5.2 12.3 7.3 5.1 12.3 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2625 PF10946.8 RUS81215.1 - 0.0033 16.5 18.6 3.8 6.5 1.5 6.1 1 1 6 8 8 8 6 Protein of unknown function DUF2625 AAA_3 PF07726.11 RUS81215.1 - 0.014 15.2 0.5 23 4.9 0.0 4.5 1 1 4 5 5 5 0 ATPase family associated with various cellular activities (AAA) DUF3959 PF13105.6 RUS81215.1 - 0.52 9.8 3.6 14 5.1 0.1 3.9 2 2 4 6 6 6 0 Protein of unknown function (DUF3959) XendoU PF09412.10 RUS81216.1 - 1.2e-67 227.9 0.0 1.4e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 RUS81216.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease Fibrinogen_C PF00147.18 RUS81217.1 - 7.7e-55 186.1 9.0 1.3e-54 185.3 9.0 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS81217.1 - 3e-06 27.2 9.8 5.7e-06 26.3 1.1 2.8 2 1 1 3 3 2 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.6 RUS81217.1 - 0.00094 19.4 11.9 0.015 15.5 3.0 3.7 1 1 3 4 4 4 3 Domain of unknown function (DUF4164) Prominin PF05478.11 RUS81217.1 - 0.027 12.4 8.6 0.038 11.9 8.6 1.1 1 0 0 1 1 1 0 Prominin Phasin PF05597.11 RUS81217.1 - 0.053 13.5 8.4 4.4 7.3 0.2 3.3 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5063 PF16702.5 RUS81217.1 - 0.17 12.3 3.2 0.42 11.0 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) SF-assemblin PF06705.11 RUS81217.1 - 0.18 11.1 16.9 0.057 12.8 10.0 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin OmpH PF03938.14 RUS81217.1 - 0.19 12.1 8.9 0.24 11.8 5.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BRI3BP PF14965.6 RUS81217.1 - 0.26 10.8 4.9 1.6 8.2 0.2 3.0 3 1 1 4 4 4 0 Negative regulator of p53/TP53 DASH_Dad1 PF08649.10 RUS81217.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad1 WXG100 PF06013.12 RUS81217.1 - 0.63 10.3 4.2 21 5.4 0.2 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF5082 PF16888.5 RUS81217.1 - 0.73 10.1 12.5 2 8.7 8.2 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 RUS81217.1 - 1.1 9.3 17.3 7.1 6.7 1.2 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4709 PF15821.5 RUS81217.1 - 1.7 9.0 6.9 1.2 9.5 1.5 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4709) Exonuc_VII_L PF02601.15 RUS81217.1 - 2.1 7.8 16.0 2.2 7.8 5.4 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 RUS81217.1 - 3 7.4 11.6 1 8.9 1.2 2.9 1 1 2 3 3 3 0 fzo-like conserved region PIN_8 PF18476.1 RUS81217.1 - 3 7.7 13.2 2.1 8.2 6.6 2.2 1 1 1 2 2 2 0 PIN like domain DUF1664 PF07889.12 RUS81217.1 - 3.3 7.8 9.8 0.75 9.9 3.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YvrJ PF12841.7 RUS81217.1 - 4 7.0 6.3 26 4.5 0.3 3.5 3 0 0 3 3 3 0 YvrJ protein family DUF2536 PF10750.9 RUS81217.1 - 4.4 7.3 8.8 1.9 8.4 1.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2536) DUF3552 PF12072.8 RUS81217.1 - 5.8 6.3 13.9 0.32 10.4 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CLZ PF16526.5 RUS81217.1 - 6.4 7.2 9.5 2.6 8.5 0.5 3.7 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GrpE PF01025.19 RUS81217.1 - 7.8 6.1 12.9 2.3 7.8 7.6 2.1 1 1 1 2 2 2 0 GrpE 7TM_GPCR_Srw PF10324.9 RUS81218.1 - 6.4e-15 55.2 7.1 2.6e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS81218.1 - 1.4e-07 31.2 11.6 5.3e-07 29.2 11.6 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS81218.1 - 2.5e-07 30.6 9.2 6e-07 29.3 7.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS81218.1 - 2.3e-05 23.9 10.9 0.032 13.6 0.1 2.8 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1189 PF06691.11 RUS81218.1 - 0.042 13.4 4.3 0.093 12.3 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF5637 PF18687.1 RUS81218.1 - 0.74 9.8 3.7 3.2 7.8 3.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5637) Bac_export_2 PF01312.19 RUS81218.1 - 0.96 8.6 0.0 0.96 8.6 0.0 2.4 3 0 0 3 3 3 0 FlhB HrpN YscU SpaS Family Serpentine_r_xa PF03383.15 RUS81218.1 - 1.1 9.2 11.6 0.064 13.2 3.5 2.8 2 1 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa DivIC PF04977.15 RUS81220.1 - 7.3 6.4 34.1 1.4 8.8 2.6 4.6 3 2 1 4 4 4 0 Septum formation initiator DUF1002 PF06207.11 RUS81220.1 - 8.9 5.8 16.6 0.67 9.4 7.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Importin_rep_6 PF18829.1 RUS81221.1 - 1.5 9.0 6.6 9.2 6.5 0.7 2.4 2 0 0 2 2 2 0 Importin repeat 6 SGT1 PF07093.11 RUS81221.1 - 7.6 4.8 8.2 0.66 8.3 2.6 1.8 2 0 0 2 2 2 0 SGT1 protein FAM176 PF14851.6 RUS81221.1 - 8.2 6.1 9.7 6.1 6.5 3.1 2.3 2 0 0 2 2 2 0 FAM176 family CHORD PF04968.12 RUS81222.1 - 2.7 8.8 12.5 1.2 9.9 8.8 2.4 2 1 0 2 2 2 0 CHORD DUF2383 PF09537.10 RUS81223.1 - 0.0054 17.1 5.4 0.026 14.8 2.9 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF2383) APG6_N PF17675.1 RUS81223.1 - 0.014 15.9 8.5 0.014 15.9 8.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CHORD PF04968.12 RUS81223.1 - 0.044 14.5 7.2 0.12 13.1 7.2 1.8 1 1 0 1 1 1 0 CHORD Mod_r PF07200.13 RUS81223.1 - 0.1 12.7 6.2 0.063 13.4 2.9 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 RUS81223.1 - 0.12 11.2 7.6 0.22 10.3 7.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2347 PF09804.9 RUS81223.1 - 0.17 11.4 0.5 0.24 11.0 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Taxilin PF09728.9 RUS81223.1 - 0.22 10.6 8.9 0.14 11.3 5.3 1.9 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Syntaxin-6_N PF09177.11 RUS81223.1 - 0.38 11.4 5.2 0.53 10.9 3.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 RUS81223.1 - 0.47 9.8 6.3 0.66 9.3 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 RUS81223.1 - 0.6 10.5 11.9 0.65 10.4 9.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 RUS81223.1 - 0.65 10.5 17.4 2.9 8.4 0.2 3.2 2 1 0 2 2 2 0 Cell division protein ZapB AIP3 PF03915.13 RUS81223.1 - 1.8 7.6 6.7 1.9 7.5 5.7 1.3 1 1 0 1 1 1 0 Actin interacting protein 3 Histone_HNS PF00816.21 RUS81223.1 - 6.1 7.7 9.7 58 4.6 10.2 2.3 2 1 0 2 2 2 0 H-NS histone family Macoilin PF09726.9 RUS81224.1 - 1.8 7.0 13.4 2.1 6.8 13.4 1.1 1 0 0 1 1 1 0 Macoilin family Mem_trans PF03547.18 RUS81224.1 - 3.8 5.8 5.6 5.2 5.3 5.6 1.1 1 0 0 1 1 1 0 Membrane transport protein GAS PF13851.6 RUS81225.1 - 0.00036 19.9 35.1 0.011 15.1 13.1 3.8 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 RUS81225.1 - 0.0055 17.2 41.1 0.2 12.2 12.5 3.2 1 1 2 3 3 3 2 Apg6 coiled-coil region JIP_LZII PF16471.5 RUS81225.1 - 0.0076 16.4 3.5 0.0076 16.4 3.5 5.0 4 1 1 5 5 5 1 JNK-interacting protein leucine zipper II Fez1 PF06818.15 RUS81225.1 - 0.25 11.8 29.8 0.073 13.5 14.0 2.3 1 1 1 2 2 2 0 Fez1 ERM PF00769.19 RUS81225.1 - 0.3 10.9 37.4 1.2 8.9 10.9 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 RUS81225.1 - 0.3 11.1 34.1 0.26 11.3 9.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 RUS81225.1 - 0.32 11.7 20.2 0.98 10.1 3.5 3.9 1 1 3 4 4 4 0 Initiation control protein YabA ATG16 PF08614.11 RUS81225.1 - 0.74 10.0 46.2 18 5.5 10.6 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 RUS81225.1 - 1.3 9.5 7.6 0.52 10.8 0.3 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 RUS81225.1 - 3.3 7.3 25.0 1.8 8.2 9.5 2.7 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 KASH_CCD PF14662.6 RUS81225.1 - 3.5 7.4 29.3 0.71 9.7 15.1 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 RUS81225.1 - 9.1 7.1 24.9 1.3 9.8 4.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) 7tm_1 PF00001.21 RUS81226.1 - 6.4e-17 61.8 0.7 2.3e-16 59.9 0.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2269 PF10027.9 RUS81226.1 - 0.27 11.3 6.5 3.3 7.7 1.4 2.5 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF4834 PF16118.5 RUS81226.1 - 6.1 7.9 7.1 29 5.7 2.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Shisa PF13908.6 RUS81227.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ANF_receptor PF01094.28 RUS81232.1 - 1.6e-16 60.4 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS81232.1 - 0.038 13.7 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Guanylate_cyc PF00211.20 RUS81233.1 - 6.3e-66 221.5 0.0 3e-64 216.0 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 RUS81233.1 - 4.7e-53 180.5 0.1 7.1e-52 176.7 0.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS81233.1 - 4.4e-37 127.8 0.0 6.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS81233.1 - 2.9e-29 102.2 0.0 5.1e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peripla_BP_6 PF13458.6 RUS81233.1 - 0.00013 21.7 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein HNOBA PF07701.14 RUS81233.1 - 0.00036 20.1 1.0 0.00059 19.3 1.0 1.3 1 0 0 1 1 1 1 Heme NO binding associated Syndecan PF01034.20 RUS81233.1 - 0.087 12.7 0.9 0.2 11.6 0.9 1.6 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 RUS81233.1 - 0.15 11.6 1.6 0.28 10.7 1.6 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MFS_1 PF07690.16 RUS81234.1 - 5e-39 134.2 10.0 6.5e-39 133.8 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS81234.1 - 1.7e-09 37.1 8.2 2.1e-09 36.8 8.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RUS81234.1 - 0.00038 19.9 2.0 0.00058 19.3 2.0 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 RUS81234.1 - 0.00041 19.0 6.0 0.00098 17.8 2.0 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Choline_transpo PF04515.12 RUS81234.1 - 0.0018 17.6 0.5 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter HCO3_cotransp PF00955.21 RUS81234.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 HCO3- transporter family Guanylate_cyc PF00211.20 RUS81236.1 - 3.6e-23 82.1 0.0 4.2e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4587 PF15248.6 RUS81237.1 - 0.032 15.0 0.0 0.08 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) ZU5 PF00791.20 RUS81238.1 - 5.7e-35 119.6 0.0 1.3e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain PDZ PF00595.24 RUS81238.1 - 8.1e-15 54.9 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Guanylate_kin PF00625.21 RUS81238.1 - 1.7e-09 37.6 0.0 1.8e-08 34.3 0.0 2.2 1 1 1 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 RUS81238.1 - 5.9e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS81238.1 - 0.0008 19.7 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tim54 PF11711.8 RUS81238.1 - 0.087 11.6 3.4 0.19 10.5 3.4 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 RUS81238.1 - 0.49 9.4 10.2 0.085 11.9 5.9 1.7 2 0 0 2 2 2 0 Solute carrier family 12 Zip PF02535.22 RUS81238.1 - 7.9 5.6 10.8 0.46 9.7 4.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 RUS81238.1 - 8.4 6.4 6.9 2.6 8.1 0.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPRY PF00622.28 RUS81239.1 - 0.033 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 SPRY domain zf-C2H2_2 PF12756.7 RUS81239.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF448 PF04296.13 RUS81239.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF448) WD-3 PF09765.9 RUS81240.1 - 0.068 12.5 1.0 0.083 12.2 1.0 1.1 1 0 0 1 1 1 0 WD-repeat region Sec2p PF06428.11 RUS81240.1 - 0.35 10.9 7.7 0.9 9.5 7.7 1.6 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p End3 PF12761.7 RUS81240.1 - 0.64 10.2 9.0 1.4 9.1 7.5 1.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF3450 PF11932.8 RUS81241.1 - 0.095 12.0 36.8 0.063 12.6 9.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 RUS81241.1 - 0.12 11.9 35.8 0.14 11.7 35.8 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 RUS81241.1 - 0.34 9.8 30.3 0.48 9.3 30.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5304 PF17230.2 RUS81241.1 - 0.52 10.5 12.6 2 8.7 12.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5304) DUF2508 PF10704.9 RUS81241.1 - 0.87 9.8 19.2 0.88 9.8 2.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2508) ZapD PF07072.11 RUS81241.1 - 1.5 8.5 19.4 0.84 9.3 4.7 2.9 1 1 2 3 3 3 0 Cell division protein DUF3584 PF12128.8 RUS81241.1 - 2 5.9 37.8 0.045 11.3 23.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ZapB PF06005.12 RUS81241.1 - 3.3 8.2 31.8 1.6 9.2 2.0 3.4 2 1 1 3 3 3 0 Cell division protein ZapB DUF2333 PF10095.9 RUS81241.1 - 4 6.4 11.8 4.6 6.1 11.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) APG6_N PF17675.1 RUS81241.1 - 6.4 7.3 37.8 4.5 7.8 11.2 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 RUS81241.1 - 7.9 5.7 29.7 13 5.0 29.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 RUS81241.1 - 8.8 4.7 13.8 11 4.4 13.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LCIB_C_CA PF18599.1 RUS81241.1 - 9.4 5.5 7.3 12 5.1 6.9 1.4 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases APC_r PF05923.12 RUS81242.1 - 8.8e-49 162.3 61.1 1.4e-09 37.4 1.6 10.3 10 0 0 10 10 10 8 APC repeat APC_rep PF18797.1 RUS81242.1 - 2.2e-22 79.8 0.3 2.2e-22 79.8 0.3 2.8 2 0 0 2 2 2 1 Adenomatous polyposis coli (APC) repeat Arm PF00514.23 RUS81242.1 - 7.5e-18 63.9 17.4 6e-06 26.1 0.4 7.5 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat APC_15aa PF05972.11 RUS81242.1 - 1.3e-14 53.4 14.6 0.00011 22.2 0.5 4.8 4 0 0 4 4 4 4 APC 15 residue motif SAMP PF05924.11 RUS81242.1 - 3.7e-05 22.9 2.2 0.00098 18.3 0.2 3.8 4 0 0 4 4 4 2 SAMP Motif Suppressor_APC PF11414.8 RUS81242.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 3.2 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein APC_N_CC PF16689.5 RUS81244.1 - 3.2e-24 84.7 3.1 3.9e-24 84.4 3.1 1.1 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain HMMR_C PF15908.5 RUS81244.1 - 0.00027 21.3 0.6 0.00034 20.9 0.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Sec2p PF06428.11 RUS81244.1 - 0.00072 19.5 1.4 0.0008 19.3 1.4 1.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 RUS81244.1 - 0.0015 18.6 1.0 0.0021 18.2 1.0 1.3 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 HALZ PF02183.18 RUS81244.1 - 0.0019 18.4 2.1 0.0039 17.4 2.1 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Leu_zip PF15294.6 RUS81244.1 - 0.0026 17.3 0.5 0.0026 17.3 0.5 1.0 1 0 0 1 1 1 1 Leucine zipper Lebercilin PF15619.6 RUS81244.1 - 0.0031 17.2 0.9 0.0036 17.0 0.9 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 RUS81244.1 - 0.0057 16.9 1.1 0.0069 16.6 1.1 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 YabA PF06156.13 RUS81244.1 - 0.0059 17.2 1.2 0.0075 16.9 1.2 1.2 1 0 0 1 1 1 1 Initiation control protein YabA DUF3450 PF11932.8 RUS81244.1 - 0.0081 15.5 0.3 0.0088 15.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 RUS81244.1 - 0.0085 16.2 1.1 0.012 15.8 1.1 1.2 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 RUS81244.1 - 0.0085 16.1 4.3 0.011 15.8 4.3 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 RUS81244.1 - 0.01 16.3 0.3 0.012 16.0 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 RUS81244.1 - 0.011 15.8 2.1 0.016 15.3 2.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor ATG16 PF08614.11 RUS81244.1 - 0.013 15.8 0.5 0.014 15.6 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 RUS81244.1 - 0.015 15.9 0.6 0.017 15.6 0.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 RUS81244.1 - 0.018 15.1 0.0 0.02 14.9 0.0 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 RUS81244.1 - 0.018 14.8 1.0 0.021 14.7 1.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 HAP1_N PF04849.13 RUS81244.1 - 0.019 14.2 1.3 0.022 14.0 1.3 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF724 PF05266.14 RUS81244.1 - 0.02 14.7 0.7 0.023 14.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 RUS81244.1 - 0.022 15.2 0.5 0.024 15.1 0.5 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF1241 PF06840.11 RUS81244.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Lipoprotein_6 PF01441.19 RUS81244.1 - 0.035 14.1 0.6 0.04 13.9 0.6 1.1 1 0 0 1 1 1 0 Lipoprotein MPS2 PF17060.5 RUS81244.1 - 0.043 13.1 0.1 0.045 13.0 0.1 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Herpes_BLRF2 PF05812.12 RUS81244.1 - 0.045 13.9 2.1 0.068 13.3 2.1 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein EzrA PF06160.12 RUS81244.1 - 0.046 11.9 0.6 0.05 11.8 0.6 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UPF0242 PF06785.11 RUS81244.1 - 0.055 13.6 0.5 0.059 13.5 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1722 PF08349.11 RUS81244.1 - 0.056 13.7 0.2 0.066 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DivIVA PF05103.13 RUS81244.1 - 0.071 13.2 0.4 0.087 12.9 0.4 1.1 1 0 0 1 1 1 0 DivIVA protein TSC22 PF01166.18 RUS81244.1 - 0.095 13.0 1.8 0.17 12.2 1.3 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family Herpes_UL6 PF01763.16 RUS81244.1 - 0.1 11.1 0.2 0.11 11.0 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like CorA PF01544.18 RUS81244.1 - 0.18 11.1 0.6 0.21 10.9 0.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 RUS81244.1 - 0.19 10.9 0.2 0.22 10.8 0.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 RUS81244.1 - 0.2 11.5 0.8 0.25 11.1 0.8 1.2 1 0 0 1 1 1 0 Septum formation initiator RUN PF02759.19 RUS81245.1 - 4.6e-10 39.6 0.1 1.3e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 RUN domain RT_RNaseH_2 PF17919.1 RUS81246.1 - 3.2e-34 116.9 0.0 5.4e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS81246.1 - 1.1e-33 115.6 0.0 1.9e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS81246.1 - 1.5e-22 80.2 0.1 2.5e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_5 PF13909.6 RUS81247.1 - 0.077 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 RUS81247.1 - 0.2 12.0 3.6 0.26 11.6 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RR_TM4-6 PF06459.12 RUS81248.1 - 0.58 9.9 3.7 1.1 9.0 3.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LPMO_10 PF03067.15 RUS81251.1 - 1.5e-39 136.7 2.4 1.8e-39 136.4 2.4 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FdhE PF04216.12 RUS81252.1 - 4.7 7.0 7.7 0.6 9.9 0.1 2.9 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Med15 PF09606.10 RUS81256.1 - 0.1 11.3 30.8 0.12 11.1 30.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ALMT PF11744.8 RUS81256.1 - 1.8 7.3 6.6 2.2 7.0 6.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 RUS81256.1 - 2.8 7.4 11.9 4.3 6.8 11.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rieske_2 PF13806.6 RUS81257.1 - 0.015 15.2 0.0 4.5 7.3 0.0 2.1 1 1 1 2 2 2 0 Rieske-like [2Fe-2S] domain Lentiviral_Tat PF02998.14 RUS81257.1 - 0.017 15.2 0.9 6.9 6.8 0.0 2.4 1 1 3 4 4 4 0 Lentiviral Tat protein nos_propeller PF18764.1 RUS81257.1 - 0.039 13.9 13.6 6.8 6.7 1.0 4.8 4 1 1 5 5 5 0 Nitrous oxide reductase propeller repeat CBP_BcsR PF10945.8 RUS81257.1 - 0.096 12.2 2.7 18 4.9 0.3 3.7 4 1 0 4 4 4 0 Cellulose biosynthesis protein BcsR Lipocalin_7 PF14651.6 RUS81257.1 - 0.89 9.5 5.4 31 4.5 0.2 3.9 1 1 3 4 4 4 0 Lipocalin / cytosolic fatty-acid binding protein family NAAA-beta PF15508.6 RUS81257.1 - 1.5 9.2 9.4 76 3.7 0.0 4.5 5 0 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Myotoxins PF00819.17 RUS81257.1 - 3.1 8.1 11.5 20 5.6 0.0 4.5 5 0 0 5 5 5 0 Myotoxin, crotamine MatE PF01554.18 RUS81259.1 - 0.074 12.7 0.9 0.1 12.2 0.9 1.1 1 0 0 1 1 1 0 MatE MH2 PF03166.14 RUS81260.1 - 4.2e-66 222.7 0.1 4.7e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 RUS81260.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Caveolin PF01146.17 RUS81261.1 - 3.4e-41 140.3 0.0 4e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 RUS81262.1 - 8.5e-42 142.3 0.2 1e-41 142.0 0.2 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 RUS81263.1 - 3.7e-46 156.4 0.0 4.3e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Caveolin Xan_ur_permease PF00860.20 RUS81263.1 - 0.13 10.9 0.8 0.16 10.7 0.8 1.1 1 0 0 1 1 1 0 Permease family Caveolin PF01146.17 RUS81264.1 - 6.2e-47 158.9 0.1 6.7e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Caveolin Xan_ur_permease PF00860.20 RUS81264.1 - 0.058 12.1 0.8 0.07 11.8 0.8 1.1 1 0 0 1 1 1 0 Permease family MgtE PF01769.16 RUS81266.1 - 1.8e-46 157.5 26.1 1.8e-24 86.5 3.0 3.3 3 0 0 3 3 3 2 Divalent cation transporter Filamin PF00630.19 RUS81267.1 - 0 1018.2 67.5 8.5e-20 71.5 0.1 20.2 20 0 0 20 20 20 20 Filamin/ABP280 repeat CH PF00307.31 RUS81267.1 - 2.1e-38 130.8 2.3 1.1e-22 80.3 1.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 RUS81267.1 - 1.4e-19 69.8 4.1 0.07 13.1 0.0 10.5 11 0 0 11 11 10 5 Y_Y_Y domain YtkA PF13115.6 RUS81267.1 - 3.9e-10 40.2 15.6 2.4 8.8 0.1 12.8 15 1 2 17 17 16 2 YtkA-like DUF5060 PF16586.5 RUS81267.1 - 4.8e-09 36.5 0.2 5.8 7.4 0.0 11.2 14 0 0 14 14 14 1 Domain of unknown function (DUF5060) Invasin_D3 PF09134.10 RUS81267.1 - 2.4e-06 27.7 27.1 8.8 6.7 0.1 12.5 13 2 1 14 14 13 1 Invasin, domain 3 Big_3_5 PF16640.5 RUS81267.1 - 2.4e-05 24.4 33.5 6.4 7.0 0.0 13.9 15 0 0 15 15 15 1 Bacterial Ig-like domain (group 3) PKD PF00801.20 RUS81267.1 - 3.6e-05 23.5 8.3 6.9 6.6 0.1 8.0 8 0 0 8 8 8 2 PKD domain Big_1 PF02369.16 RUS81267.1 - 0.00055 19.9 3.5 19 5.4 0.2 7.7 11 0 0 11 11 10 0 Bacterial Ig-like domain (group 1) DUF971 PF06155.12 RUS81267.1 - 0.018 15.6 0.0 88 3.8 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF971) CAMSAP_CH PF11971.8 RUS81267.1 - 0.02 14.7 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain DUF4369 PF14289.6 RUS81267.1 - 0.062 13.8 0.8 4.7 7.8 0.1 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4369) SprB PF13573.6 RUS81267.1 - 0.069 12.9 7.2 8.2 6.3 0.1 5.1 5 0 0 5 5 5 0 SprB repeat GldM_C PF12080.8 RUS81267.1 - 0.14 12.3 10.7 3.5 7.8 0.0 5.7 6 0 0 6 6 5 0 GldM C-terminal domain RNA_pol_Rpc4 PF05132.14 RUS81268.1 - 0.00026 21.4 12.1 0.00026 21.4 12.1 1.6 2 0 0 2 2 2 1 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 RUS81268.1 - 0.026 14.4 21.5 0.037 13.9 21.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RUS81268.1 - 0.048 13.8 8.6 0.064 13.4 8.6 1.3 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 RUS81268.1 - 0.36 10.5 23.8 0.6 9.8 23.8 1.3 1 0 0 1 1 1 0 Connexin DUF3405 PF11885.8 RUS81268.1 - 1.3 7.5 13.1 1.6 7.3 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Otopetrin PF03189.13 RUS81268.1 - 1.8 7.3 5.6 2.2 7.0 5.6 1.2 1 0 0 1 1 1 0 Otopetrin SRP-alpha_N PF04086.13 RUS81268.1 - 2.7 7.8 33.4 0.44 10.4 29.8 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 RUS81268.1 - 4.8 5.8 15.8 6.5 5.4 15.8 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 RUS81269.1 - 0.0063 14.9 5.4 0.0078 14.6 5.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 RUS81269.1 - 0.13 10.3 12.1 0.19 9.8 12.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi XPC-binding PF09280.11 RUS81269.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 XPC-binding domain YL1 PF05764.13 RUS81269.1 - 0.33 11.0 16.2 0.73 9.9 16.2 1.5 1 1 0 1 1 1 0 YL1 nuclear protein Pes-10 PF07149.11 RUS81269.1 - 0.72 8.9 4.2 0.91 8.5 4.2 1.1 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 RUS81269.1 - 6.5 5.2 8.1 8.5 4.8 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 RUS81269.1 - 7.9 7.5 17.5 23 6.0 17.5 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SEFIR PF08357.11 RUS81270.1 - 5.6e-07 30.0 0.0 1.3e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 SEFIR domain PgaPase_1 PF06162.12 RUS81271.1 - 0.024 14.4 0.3 0.04 13.7 0.3 1.3 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 Cadherin PF00028.17 RUS81272.1 - 4.6e-16 59.0 1.7 2.6e-08 34.2 0.4 2.3 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 RUS81272.1 - 0.00012 22.1 1.1 0.0034 17.3 0.5 2.3 2 0 0 2 2 2 2 Cadherin-like EMC3_TMCO1 PF01956.16 RUS81273.1 - 3.4e-06 26.9 2.0 2e-05 24.4 0.2 2.1 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like GMC_oxred_N PF00732.19 RUS81274.1 - 3.1e-45 154.8 0.0 3.5e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 RUS81274.1 - 3.1e-05 24.1 2.6 6.7e-05 23.0 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RUS81274.1 - 3.2e-05 23.2 0.1 4.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RUS81274.1 - 0.0015 18.2 1.0 0.002 17.8 1.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS81274.1 - 0.0021 17.2 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS81274.1 - 0.0048 16.2 0.0 0.0057 15.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS81274.1 - 0.029 13.6 0.1 0.043 13.0 0.1 1.1 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 RUS81274.1 - 0.048 12.3 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 RUS81274.1 - 0.19 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Epimerase PF01370.21 RUS81275.1 - 1.6e-53 181.6 0.0 2.6e-53 181.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS81275.1 - 1.9e-10 40.6 0.7 1.4e-09 37.9 0.0 2.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS81275.1 - 1.2e-06 27.9 0.0 2.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS81275.1 - 0.0003 20.0 2.0 0.0067 15.6 0.0 2.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Endonuc-FokI_C PF09254.11 RUS81275.1 - 0.047 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Epimerase PF01370.21 RUS81276.1 - 3.4e-51 174.0 0.0 4.5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS81276.1 - 2.7e-09 36.9 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS81276.1 - 6.6e-07 28.7 0.0 2.7e-06 26.7 0.0 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS81276.1 - 0.004 16.3 1.0 0.0089 15.2 0.1 1.9 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 RUS81277.1 - 9.7e-54 182.4 0.0 1.2e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS81277.1 - 1.6e-11 44.2 0.3 7.5e-11 42.0 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS81277.1 - 2.2e-06 27.0 0.0 5.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS81277.1 - 0.0017 17.6 4.1 0.0052 16.0 0.0 2.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS81277.1 - 0.064 12.4 1.5 0.1 11.8 0.0 1.9 1 1 0 2 2 2 0 Male sterility protein GCFC PF07842.12 RUS81278.1 - 1.4e-27 97.1 0.4 7.1e-27 94.7 0.4 2.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Herpes_UL56 PF04534.12 RUS81278.1 - 0.052 13.0 5.5 0.11 12.0 5.5 1.5 1 0 0 1 1 1 0 Herpesvirus UL56 protein Glyco_transf_92 PF01697.27 RUS81279.1 - 1.4e-38 133.1 0.2 3.1e-38 131.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 92 DUF4578 PF15147.6 RUS81279.1 - 0.11 13.3 1.8 0.22 12.4 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Glyco_tranf_2_4 PF13704.6 RUS81279.1 - 0.15 12.5 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 MRVI1 PF05781.12 RUS81280.1 - 7.4e-47 160.2 8.6 7.4e-47 160.2 8.6 3.2 3 1 0 3 3 3 2 MRVI1 protein TBCC_N PF16752.5 RUS81280.1 - 0.014 15.9 0.5 0.014 15.9 0.5 3.3 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Spc7 PF08317.11 RUS81280.1 - 0.07 12.0 2.3 0.21 10.4 0.3 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 RUS81280.1 - 0.35 10.9 4.6 3.3 7.8 0.4 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lipocalin_2 PF08212.12 RUS81281.1 - 1.1e-21 77.2 0.0 6.7e-11 42.3 0.0 2.2 1 1 1 2 2 2 2 Lipocalin-like domain Lipocalin PF00061.23 RUS81281.1 - 1.2e-13 51.5 0.0 2.4e-10 40.8 0.0 2.1 1 1 1 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 RUS81282.1 - 1.8e-14 53.9 0.0 2.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS81282.1 - 7.3e-09 36.0 0.0 1.3e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family YjcQ PF09639.10 RUS81283.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 YjcQ protein DUF2982 PF11201.8 RUS81284.1 - 4.2e-05 23.1 1.0 17 5.0 0.0 4.8 1 1 5 6 6 6 3 Protein of unknown function (DUF2982) DUF4976 PF16347.5 RUS81284.1 - 0.00018 21.7 12.9 3.5 7.9 0.1 5.6 1 1 4 6 6 6 3 Domain of unknown function (DUF4976) Alpha-2-MRAP_C PF06401.11 RUS81284.1 - 0.0004 20.4 3.1 16 5.4 0.1 5.1 1 1 3 5 5 5 1 Alpha-2-macroglobulin RAP, C-terminal domain CENP-L PF13092.6 RUS81284.1 - 0.0016 18.6 3.8 18 5.5 2.0 5.3 1 1 1 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 AFOR_C PF01314.18 RUS81284.1 - 0.0069 15.4 0.9 4 6.4 0.9 3.9 1 1 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DNA_pol_lambd_f PF10391.9 RUS81284.1 - 0.044 13.6 5.7 1.1e+02 2.7 0.0 5.6 6 0 0 6 6 6 0 Fingers domain of DNA polymerase lambda PrcB_C PF14343.6 RUS81284.1 - 0.72 10.0 15.5 74 3.6 0.3 7.7 1 1 5 7 7 7 0 PrcB C-terminal HpcH_HpaI PF03328.14 RUS81284.1 - 8.4 5.5 8.1 31 3.6 1.4 2.9 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Acyltransf_C PF16076.5 RUS81285.1 - 2.9e-24 84.9 0.0 5.1e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 RUS81285.1 - 4.4e-11 42.5 0.0 8.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CDC45 PF02724.14 RUS81286.1 - 0.0056 15.0 13.5 0.0081 14.5 13.5 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF2457 PF10446.9 RUS81286.1 - 0.027 13.6 39.7 0.039 13.1 33.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CPSF100_C PF13299.6 RUS81286.1 - 0.038 14.2 2.9 0.25 11.5 2.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 RUS81286.1 - 0.1 11.0 15.2 0.17 10.3 15.2 1.3 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS81286.1 - 0.16 11.4 18.2 0.28 10.6 18.2 1.3 1 0 0 1 1 1 0 SDA1 FPN1 PF06963.12 RUS81286.1 - 0.26 9.8 0.1 0.42 9.1 0.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) IFT57 PF10498.9 RUS81286.1 - 0.28 10.1 10.9 0.49 9.3 10.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sporozoite_P67 PF05642.11 RUS81286.1 - 0.49 8.4 7.4 0.75 7.8 7.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 RUS81286.1 - 2.5 6.8 4.0 0.72 8.6 1.3 1.4 2 0 0 2 2 2 0 Presenilin Secretin_N_2 PF07655.13 RUS81286.1 - 7.7 7.1 18.4 14 6.3 18.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain UL45 PF05473.12 RUS81291.1 - 0.002 17.8 2.8 0.066 12.9 0.0 2.3 2 1 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like Beta-lactamase PF00144.24 RUS81292.1 - 3.4e-35 121.8 1.2 1.7e-17 63.7 0.5 2.2 1 1 1 2 2 2 2 Beta-lactamase MIEAP PF16026.5 RUS81293.1 - 2.7e-46 158.3 0.1 2.3e-45 155.2 0.0 2.5 3 0 0 3 3 3 1 Mitochondria-eating protein TMF_TATA_bd PF12325.8 RUS81293.1 - 0.012 15.8 1.8 0.055 13.7 0.7 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tektin PF03148.14 RUS81293.1 - 0.05 12.4 0.7 0.095 11.4 0.7 1.4 1 0 0 1 1 1 0 Tektin family Rabaptin PF03528.15 RUS81293.1 - 0.073 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Rabaptin Uso1_p115_C PF04871.13 RUS81293.1 - 0.095 13.1 0.3 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 RUS81293.1 - 0.13 12.5 4.1 0.26 11.5 4.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Takusan PF04822.13 RUS81293.1 - 0.14 12.1 0.3 0.4 10.6 0.3 1.8 1 0 0 1 1 1 0 Takusan DivIC PF04977.15 RUS81293.1 - 0.19 11.5 3.2 0.44 10.4 3.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Amino_oxidase PF01593.24 RUS81295.1 - 8e-14 51.8 0.6 2.3e-12 47.0 0.6 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS81295.1 - 8e-12 45.2 0.1 2.2e-10 40.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS81295.1 - 6.1e-07 28.9 0.5 1.3e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 RUS81295.1 - 1.1e-06 28.5 5.8 7.8e-05 22.4 5.8 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS81295.1 - 3e-06 26.7 0.1 0.00097 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS81295.1 - 7.7e-06 25.2 3.3 9.2e-05 21.7 2.8 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 RUS81295.1 - 2.9e-05 23.3 2.7 0.017 14.2 1.4 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RUS81295.1 - 4.7e-05 22.8 0.2 0.00015 21.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 RUS81295.1 - 6.9e-05 22.4 0.1 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS81295.1 - 0.00036 21.0 1.2 0.024 15.2 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RUS81295.1 - 0.00041 19.5 4.3 0.45 9.5 1.3 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 RUS81295.1 - 0.002 16.9 1.8 0.0056 15.4 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 RUS81295.1 - 0.0092 15.3 0.7 0.015 14.6 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 RUS81295.1 - 0.015 13.9 0.0 3 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.14 RUS81295.1 - 0.048 12.5 0.2 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase SpoU_sub_bind PF08032.12 RUS81295.1 - 0.17 12.2 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Ion_trans PF00520.31 RUS81296.1 - 1.7e-05 24.2 0.3 2.1e-05 23.9 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein Na_trans_cytopl PF11933.8 RUS81296.1 - 0.00035 20.5 6.3 0.0018 18.1 6.3 1.9 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Zip PF02535.22 RUS81296.1 - 0.025 13.8 0.0 0.025 13.8 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0239 PF06783.11 RUS81296.1 - 0.03 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) GRP PF07172.11 RUS81296.1 - 0.091 13.5 4.7 0.6 10.8 4.7 2.0 1 1 0 1 1 1 0 Glycine rich protein family Rpn3_C PF08375.11 RUS81296.1 - 0.12 12.8 2.2 0.22 12.0 2.2 1.3 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal FSAP_sig_propep PF03032.15 RUS81296.1 - 0.21 11.7 6.8 0.15 12.1 3.8 2.2 2 1 0 2 2 2 0 Frog skin active peptide family signal and propeptide DUF1154 PF06631.11 RUS81297.1 - 5.1e-14 52.0 4.0 5.1e-14 52.0 4.0 3.9 5 1 0 5 5 5 1 Protein of unknown function (DUF1154) C2 PF00168.30 RUS81297.1 - 1.8e-05 25.0 0.0 4.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Integrase_H2C2 PF17921.1 RUS81298.1 - 1.5e-09 37.8 0.7 1.5e-09 37.8 0.7 4.1 7 0 0 7 7 7 1 Integrase zinc binding domain FhuF_C PF11575.8 RUS81298.1 - 1.1e-05 25.2 20.9 6.8 6.7 0.1 7.4 7 0 0 7 7 7 6 FhuF 2Fe-2S C-terminal domain zf-H2C2 PF09337.10 RUS81298.1 - 0.062 13.5 1.8 0.062 13.5 1.8 6.7 7 0 0 7 7 7 0 H2C2 zinc finger RANK_CRD_2 PF18278.1 RUS81298.1 - 1.1 9.5 24.0 57 4.0 0.1 6.3 6 0 0 6 6 6 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Toxin_5 PF05294.13 RUS81298.1 - 4.9 7.7 27.5 99 3.5 0.1 7.3 8 0 0 8 8 8 0 Scorpion short toxin Na_H_Exchanger PF00999.21 RUS81299.1 - 1.4e-83 280.9 39.8 1.8e-83 280.4 39.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NiFe_hyd_3_EhaA PF17367.2 RUS81299.1 - 4.6 7.5 6.5 13 6.0 0.6 3.1 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A Death PF00531.22 RUS81300.1 - 4e-13 49.3 0.4 5.5e-13 48.9 0.4 1.2 1 0 0 1 1 1 1 Death domain DUF2252 PF10009.9 RUS81300.1 - 0.059 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) LmjF365940-deam PF14421.6 RUS81300.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases DEAD PF00270.29 RUS81301.1 - 1.2e-13 51.2 0.0 4.3e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS81301.1 - 9.7e-13 48.4 0.0 1.7e-10 41.2 0.0 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS81301.1 - 3.8e-09 36.8 0.0 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 RUS81301.1 - 2e-06 28.3 0.0 5.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 RUS81301.1 - 0.00013 21.7 0.0 0.0015 18.3 0.0 2.7 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.6 RUS81301.1 - 0.044 14.0 0.2 0.15 12.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) T2SSE PF00437.20 RUS81301.1 - 0.091 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Hexokinase_2 PF03727.16 RUS81302.1 - 2.2e-71 240.1 0.0 2.8e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RUS81302.1 - 1.9e-68 230.3 0.0 2.7e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Big_3_5 PF16640.5 RUS81303.1 - 0.00019 21.5 3.6 0.31 11.2 0.3 2.9 1 1 2 3 3 3 3 Bacterial Ig-like domain (group 3) SecA_SW PF07516.13 RUS81303.1 - 0.0002 21.5 1.2 1.1e+02 2.7 0.0 6.1 5 3 2 8 8 8 0 SecA Wing and Scaffold domain IPI_T4 PF11634.8 RUS81303.1 - 0.0016 18.4 1.8 47 4.1 0.0 5.3 1 1 4 5 5 5 2 Nuclease inhibitor from bacteriophage T4 DUF1235 PF06822.12 RUS81304.1 - 0.025 13.9 0.1 0.63 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1235) SplA PF11132.8 RUS81304.1 - 0.031 14.0 18.4 15 5.4 0.2 6.0 1 1 6 8 8 8 0 Transcriptional regulator protein (SplA) DUF4813 PF16072.5 RUS81304.1 - 0.36 10.5 5.9 9 5.9 0.1 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4813) Atg14 PF10186.9 RUS81304.1 - 0.67 9.0 7.8 3.1e+02 0.2 7.8 3.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CH PF00307.31 RUS81306.1 - 5.4e-15 55.5 0.0 7.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS81306.1 - 0.045 13.6 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 CAMSAP CH domain Sulfotransfer_1 PF00685.27 RUS81308.1 - 6.8e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS81308.1 - 1.3e-11 45.3 0.0 6.8e-07 29.9 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS81308.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family TMEM101 PF15111.6 RUS81309.1 - 9.5e-51 172.8 5.3 1.2e-50 172.4 5.3 1.0 1 0 0 1 1 1 1 TMEM101 protein family DUF2339 PF10101.9 RUS81309.1 - 0.0051 15.5 2.2 0.0076 14.9 2.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF1129 PF06570.11 RUS81309.1 - 0.016 14.7 0.2 0.039 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PhoR PF11808.8 RUS81309.1 - 0.026 14.9 3.6 0.28 11.6 0.2 2.9 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR TrbC PF04956.13 RUS81309.1 - 0.032 14.5 2.5 0.14 12.4 0.3 2.7 3 0 0 3 3 3 0 TrbC/VIRB2 family SPC12 PF06645.13 RUS81309.1 - 0.054 13.6 1.9 1.4 9.0 0.5 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF368 PF04018.13 RUS81309.1 - 0.086 12.4 1.3 0.18 11.4 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF368) SirB PF04247.12 RUS81309.1 - 0.5 10.5 8.1 0.2 11.7 0.5 3.2 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB DENN PF02141.21 RUS81310.1 - 5.5e-34 117.7 1.7 2.2e-33 115.8 0.8 2.4 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 RUS81310.1 - 7.3e-19 68.3 0.2 2.3e-18 66.7 0.2 2.0 1 0 0 1 1 1 1 uDENN domain PglZ PF08665.12 RUS81310.1 - 0.23 11.5 0.7 0.46 10.6 0.7 1.4 1 0 0 1 1 1 0 PglZ domain TFIIA PF03153.13 RUS81311.1 - 1.1e-06 29.0 14.1 1.3e-06 28.7 14.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 RUS81311.1 - 0.031 13.1 2.9 0.039 12.7 2.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.8 RUS81311.1 - 0.088 12.5 3.6 0.19 11.4 3.7 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myc-LZ PF02344.15 RUS81311.1 - 0.27 11.4 4.8 8.1 6.6 2.0 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain DUF2514 PF10721.9 RUS81311.1 - 0.91 9.5 5.7 13 5.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Synaptobrevin PF00957.21 RUS81311.1 - 0.93 9.3 2.6 8 6.3 0.8 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF2968 PF11180.8 RUS81311.1 - 2.3 7.8 6.8 3.9 7.1 6.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) RVT_1 PF00078.27 RUS81312.1 - 8.3e-29 100.7 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4085 PF13315.6 RUS81313.1 - 0.064 12.9 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) RR_TM4-6 PF06459.12 RUS81314.1 - 0.35 10.6 13.6 0.59 9.9 13.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 RUS81314.1 - 0.38 11.1 8.8 0.63 10.3 8.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 RUS81314.1 - 0.51 10.8 5.1 1 9.7 5.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 RUS81314.1 - 0.78 7.9 16.8 1 7.5 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 RUS81314.1 - 1.2 8.3 14.0 2 7.7 14.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 RUS81314.1 - 1.4 7.8 4.5 2.3 7.1 4.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 RUS81314.1 - 1.7 8.0 7.2 3.2 7.1 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_3_Rpc31 PF11705.8 RUS81314.1 - 2.9 8.1 21.9 5.1 7.3 21.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 RUS81314.1 - 2.9 7.8 16.0 4.8 7.1 16.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 RUS81314.1 - 4.9 6.9 16.2 8.8 6.1 16.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 RUS81314.1 - 7.7 5.6 10.9 11 5.1 10.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_polI_A34 PF08208.11 RUS81314.1 - 7.7 6.6 19.1 14 5.7 19.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 7tm_1 PF00001.21 RUS81316.1 - 1.1e-06 28.1 5.2 1.1e-06 28.1 5.2 2.9 2 1 0 2 2 1 1 7 transmembrane receptor (rhodopsin family) EOS1 PF12326.8 RUS81316.1 - 0.0015 18.5 5.3 0.0028 17.6 5.0 1.5 1 1 0 1 1 1 1 N-glycosylation protein YL1 PF05764.13 RUS81316.1 - 0.017 15.2 27.2 0.023 14.8 27.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PcfK PF14058.6 RUS81316.1 - 0.081 13.2 26.5 0.15 12.4 26.5 1.5 1 0 0 1 1 1 0 PcfK-like protein GAGA_bind PF06217.12 RUS81316.1 - 0.084 13.2 20.6 0.12 12.7 20.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family LicD PF04991.13 RUS81316.1 - 0.11 12.6 15.2 0.17 12.0 15.2 1.2 1 0 0 1 1 1 0 LicD family RR_TM4-6 PF06459.12 RUS81316.1 - 0.12 12.2 21.8 0.17 11.7 21.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RUS81316.1 - 0.13 12.4 6.6 0.18 12.0 6.6 1.2 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.11 RUS81316.1 - 0.35 10.9 50.6 0.64 10.1 50.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 RUS81316.1 - 0.45 10.8 30.8 0.66 10.3 30.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.7 RUS81316.1 - 0.49 10.6 25.2 0.68 10.2 25.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNA_pol_Rpc4 PF05132.14 RUS81316.1 - 0.64 10.4 19.5 0.99 9.8 19.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 RUS81316.1 - 0.96 8.6 6.4 1.7 7.8 6.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter SRP-alpha_N PF04086.13 RUS81316.1 - 1.4 8.8 29.9 2 8.3 29.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SLC12 PF03522.15 RUS81316.1 - 2.6 7.0 16.7 3.6 6.5 16.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 RUS81316.1 - 2.8 7.7 21.3 5.8 6.6 21.3 1.6 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 RUS81316.1 - 3 7.7 34.1 4.4 7.2 34.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_11 PF13086.6 RUS81316.1 - 4.1 7.1 15.2 5.7 6.6 15.2 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 RUS81316.1 - 4.4 5.5 20.0 5.6 5.1 20.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 RUS81316.1 - 6.7 6.1 19.9 10 5.5 19.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 RUS81316.1 - 7 5.3 20.9 10 4.8 20.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-N PF05238.13 RUS81316.1 - 9.1 5.5 20.5 13 4.9 20.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Gaa1 PF04114.14 RUS81317.1 - 0.015 14.3 0.3 0.018 14.1 0.3 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Shisa PF13908.6 RUS81318.1 - 0.05 13.9 0.1 0.075 13.3 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Vma12 PF11712.8 RUS81318.1 - 0.074 13.1 0.9 0.14 12.2 0.9 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ost4 PF10215.9 RUS81318.1 - 0.36 10.7 2.3 0.82 9.5 2.3 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase EphA2_TM PF14575.6 RUS81318.1 - 1.9 9.4 3.4 0.82 10.6 0.3 2.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain CBAH PF02275.18 RUS81319.1 - 1.1e-29 104.1 0.0 2.5e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 RUS81319.1 - 2.2e-16 59.9 0.0 1.1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Gal-bind_lectin PF00337.22 RUS81321.1 - 5.7e-14 51.8 0.0 8.4e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Syndecan PF01034.20 RUS81322.1 - 2.2e-05 24.3 0.1 4.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 RUS81322.1 - 0.0021 18.1 1.3 0.0089 16.0 1.1 2.1 1 1 1 2 2 2 1 Protocadherin EphA2_TM PF14575.6 RUS81322.1 - 5.8 7.9 6.3 4 8.4 3.6 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-C3HC4_3 PF13920.6 RUS81323.1 - 8.5e-14 51.2 11.6 8.5e-14 51.2 11.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 RUS81323.1 - 0.0032 16.7 3.1 0.0032 16.7 3.1 2.8 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 RUS81323.1 - 0.0079 16.5 9.7 0.0079 16.5 9.7 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RUS81323.1 - 0.032 14.1 9.8 0.1 12.5 9.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 RUS81323.1 - 0.077 13.0 10.5 1.6 8.8 4.7 3.0 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 RUS81323.1 - 0.24 11.4 10.6 0.69 9.9 10.6 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 RUS81323.1 - 0.86 9.9 7.3 2.8 8.3 7.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RUS81323.1 - 0.89 9.5 10.1 2.3 8.1 10.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rod_cone_degen PF15201.6 RUS81325.1 - 7 6.8 8.9 1.8 8.7 0.5 3.7 3 1 1 4 4 4 0 Progressive rod-cone degeneration polyprenyl_synt PF00348.17 RUS81327.1 - 6.3e-60 202.4 0.1 7.3e-60 202.2 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase QVR PF17064.5 RUS81328.1 - 2.1e-20 72.8 7.2 2.5e-20 72.5 7.2 1.1 1 0 0 1 1 1 1 Sleepless protein LRR_6 PF13516.6 RUS81329.1 - 2.7e-11 42.6 1.2 0.00098 19.0 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 RUS81329.1 - 0.001 19.3 0.6 4.2 8.3 0.0 4.3 3 1 0 3 3 3 1 Leucine Rich Repeat SAPS PF04499.15 RUS81330.1 - 0.0034 16.2 6.3 0.003 16.4 6.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS81330.1 - 0.039 12.2 44.4 0.052 11.8 44.4 1.1 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 RUS81330.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 RUS81330.1 - 0.32 8.9 0.1 0.39 8.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 RUS81330.1 - 1.1 7.9 2.0 1.5 7.5 2.0 1.2 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 RUS81330.1 - 5.5 6.8 15.2 11 5.8 15.2 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Paf1 PF03985.13 RUS81330.1 - 7.7 5.4 23.1 11 4.9 23.1 1.3 1 0 0 1 1 1 0 Paf1 SKICH PF17751.1 RUS81332.1 - 3.5e-17 62.8 0.0 8.6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 SKICH domain Rubredoxin PF00301.20 RUS81332.1 - 0.059 13.4 5.8 0.025 14.6 1.5 2.3 2 0 0 2 2 2 0 Rubredoxin MDMPI_C PF07398.11 RUS81332.1 - 7.4 7.5 6.8 2.2 9.2 1.7 2.8 2 0 0 2 2 2 0 MDMPI C-terminal domain TBCA PF02970.16 RUS81335.1 - 1.4e-08 35.0 0.6 1.6 9.2 0.1 4.4 1 1 3 4 4 4 3 Tubulin binding cofactor A HisKA_3 PF07730.13 RUS81335.1 - 9.9e-05 22.8 0.0 6.5 7.3 0.0 3.6 1 1 2 3 3 3 0 Histidine kinase CODH_A_N PF18537.1 RUS81335.1 - 0.00046 20.1 1.1 6.5 6.9 1.0 4.5 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain MSG PF02349.15 RUS81335.1 - 0.0016 18.6 42.3 0.2 11.9 7.4 4.2 1 1 3 4 4 4 3 Major surface glycoprotein YscO PF07321.12 RUS81335.1 - 0.0017 18.4 2.2 4.6 7.2 0.0 3.5 1 1 3 4 4 4 0 Type III secretion protein YscO N6_N4_Mtase PF01555.18 RUS81335.1 - 0.0048 16.6 0.7 3.1 7.4 0.1 3.7 1 1 1 2 2 2 1 DNA methylase HrpB7 PF09486.10 RUS81335.1 - 0.0062 16.9 0.2 4.7 7.6 0.0 3.1 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DHC_N1 PF08385.12 RUS81335.1 - 0.007 15.1 2.0 0.0085 14.8 2.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Methyltransf_12 PF08242.12 RUS81335.1 - 0.0095 16.7 4.6 26 5.6 1.8 4.1 2 1 0 2 2 2 0 Methyltransferase domain Brix PF04427.18 RUS81335.1 - 0.0096 16.0 7.1 0.11 12.6 1.3 2.7 1 1 2 3 3 3 1 Brix domain SesA PF17107.5 RUS81335.1 - 0.0098 16.1 5.0 0.43 10.8 1.1 2.2 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases DASH_Spc19 PF08287.11 RUS81335.1 - 0.013 15.4 15.3 0.58 10.0 2.8 3.7 1 1 2 3 3 3 0 Spc19 Med28 PF11594.8 RUS81335.1 - 0.015 15.4 0.1 1.3 9.1 0.0 2.7 1 1 1 2 2 2 0 Mediator complex subunit 28 BAR PF03114.18 RUS81335.1 - 0.021 14.5 0.2 2.3 7.8 0.1 2.4 1 1 1 2 2 2 0 BAR domain ALIX_LYPXL_bnd PF13949.6 RUS81335.1 - 0.021 14.1 3.7 7.2 5.8 0.2 3.3 1 1 3 4 4 4 0 ALIX V-shaped domain binding to HIV Laminin_I PF06008.14 RUS81335.1 - 0.022 14.5 0.0 1.5 8.5 0.0 2.4 1 1 1 2 2 2 0 Laminin Domain I TMPIT PF07851.13 RUS81335.1 - 0.023 13.9 0.1 0.064 12.5 0.1 1.8 1 1 0 1 1 1 0 TMPIT-like protein Sec5 PF15469.6 RUS81335.1 - 0.026 14.3 0.1 3 7.6 0.1 2.4 1 1 1 2 2 2 0 Exocyst complex component Sec5 PLU-1 PF08429.11 RUS81335.1 - 0.033 13.4 1.7 0.22 10.6 0.4 2.3 1 1 1 2 2 2 0 PLU-1-like protein FH2 PF02181.23 RUS81335.1 - 0.038 13.1 0.5 0.095 11.8 0.2 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain APG17 PF04108.12 RUS81335.1 - 0.042 13.0 0.0 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 PRESAN PF09687.10 RUS81335.1 - 0.046 14.3 8.9 0.84 10.2 3.1 2.3 1 1 1 2 2 2 0 Plasmodium RESA N-terminal BAR_3 PF16746.5 RUS81335.1 - 0.066 12.9 0.5 0.64 9.7 0.4 2.1 1 1 1 2 2 2 0 BAR domain of APPL family GCIP PF13324.6 RUS81335.1 - 0.072 12.7 5.8 2.5 7.7 0.4 2.9 1 1 2 3 3 3 0 Grap2 and cyclin-D-interacting MukF_M PF17192.4 RUS81335.1 - 0.077 12.7 2.2 2.6 7.8 0.1 2.5 1 1 2 3 3 3 0 MukF middle domain 14-3-3 PF00244.20 RUS81335.1 - 0.099 12.1 3.0 0.13 11.7 2.8 1.4 1 1 0 1 1 1 0 14-3-3 protein Sec34 PF04136.15 RUS81335.1 - 0.1 12.5 2.4 1.5 8.7 0.1 2.6 1 1 2 3 3 3 0 Sec34-like family DUF883 PF05957.13 RUS81335.1 - 0.13 12.9 0.1 11 6.7 0.0 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EzrA PF06160.12 RUS81335.1 - 0.15 10.2 0.0 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Imm6 PF14434.6 RUS81335.1 - 0.25 11.3 5.5 20 5.2 0.1 3.7 1 1 1 2 2 2 0 Immunity protein Imm6 DUF3740 PF12548.8 RUS81335.1 - 0.34 11.4 15.1 0.68 10.4 0.7 3.5 1 1 2 3 3 3 0 Sulfatase protein Nuclease_act PF08133.11 RUS81335.1 - 0.34 11.2 4.8 45 4.5 0.1 4.8 4 1 1 5 5 4 0 Anticodon nuclease activator family DUF2684 PF10885.8 RUS81335.1 - 0.47 10.6 2.1 31 4.8 0.2 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2684) PMEI PF04043.15 RUS81335.1 - 0.69 10.3 16.7 0.75 10.1 7.7 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DBINO PF13892.6 RUS81335.1 - 0.7 10.3 8.0 3.9 7.8 0.9 2.4 1 1 1 2 2 2 0 DNA-binding domain RRF PF01765.19 RUS81335.1 - 1.2 9.1 4.6 6 6.8 3.9 2.3 1 1 0 1 1 1 0 Ribosome recycling factor DUF1678 PF07913.11 RUS81335.1 - 1.2 8.9 9.4 4 7.2 0.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1678) DUF4208 PF13907.6 RUS81335.1 - 1.6 9.3 8.9 43 4.6 0.1 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) RPW8 PF05659.11 RUS81335.1 - 1.8 8.3 8.7 0.3 10.8 3.4 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 7tm_1 PF00001.21 RUS81336.1 - 2.4e-25 89.3 14.9 2.4e-25 89.3 14.9 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS81336.1 - 2.6e-18 66.4 19.3 3.7e-18 65.9 19.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2304 PF10066.9 RUS81336.1 - 8.6 6.6 10.9 7.2 6.9 0.6 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Cu_amine_oxid PF01179.20 RUS81337.1 - 1.2e-47 162.8 0.1 1.3e-47 162.6 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Methyltransf_22 PF13383.6 RUS81340.1 - 5.6e-14 52.3 0.0 6.3e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS81340.1 - 3e-07 30.6 0.5 5.3e-07 29.8 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain FGFR3_TM PF18123.1 RUS81341.1 - 0.1 12.2 1.9 0.22 11.1 1.9 1.5 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain PSP PF04046.16 RUS81342.1 - 1.8e-09 37.3 9.0 7.9 6.4 0.0 11.9 12 1 1 13 13 13 3 PSP Phage_holin_2_4 PF16082.5 RUS81342.1 - 0.24 11.2 9.8 1.3e+02 2.4 0.0 8.7 12 0 0 12 12 12 0 Bacteriophage holin family, superfamily II-like FANCI_S4 PF14678.6 RUS81343.1 - 0.036 13.2 0.2 0.046 12.8 0.2 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 Lipase PF00151.19 RUS81344.1 - 3.8e-61 207.2 0.0 5.4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS81344.1 - 0.00038 21.1 0.9 0.00074 20.2 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS81344.1 - 0.0019 17.9 0.3 0.0068 16.1 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold DMT_6 PF04342.12 RUS81344.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) Pkinase PF00069.25 RUS81346.1 - 2.7e-08 33.5 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81346.1 - 0.00062 19.1 0.0 0.00093 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF677 PF05055.12 RUS81346.1 - 0.036 12.9 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) GDA1_CD39 PF01150.17 RUS81346.1 - 0.17 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 RUS81347.1 - 6.5e-20 71.6 0.0 6.5e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 RUS81348.1 - 1.4e-50 169.8 2.7 5.4e-18 65.4 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS81348.1 - 1.2e-49 166.1 13.3 2.2e-10 40.9 0.1 5.7 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS81348.1 - 2.4e-39 132.1 8.8 4.1e-07 30.1 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 RUS81348.1 - 5.6e-36 122.1 5.7 3.2e-08 33.7 0.1 7.3 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81348.1 - 8e-35 114.9 2.6 0.0003 21.0 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Nif11 PF07862.11 RUS81348.1 - 0.16 12.3 0.9 2.3 8.6 0.1 2.9 2 0 0 2 2 2 0 Nif11 domain Fe-S_biosyn PF01521.20 RUS81349.1 - 4.9e-15 55.7 0.2 6e-15 55.4 0.2 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 RUS81349.1 - 0.082 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) ADIP PF11559.8 RUS81350.1 - 0.022 14.9 2.2 0.022 14.9 2.2 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Cytochrom_C_2 PF01322.20 RUS81350.1 - 0.32 11.9 6.9 0.078 13.9 2.6 2.2 3 0 0 3 3 3 0 Cytochrome C' Pkinase PF00069.25 RUS81351.1 - 4.4e-75 252.5 0.0 6.9e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81351.1 - 7.8e-44 149.9 0.0 1.4e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 RUS81351.1 - 1.5e-14 54.5 0.2 5.3e-14 52.7 0.1 2.0 3 0 0 3 3 3 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 RUS81351.1 - 4.2e-07 29.6 0.0 1.3e-06 28.0 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS81351.1 - 0.002 17.7 0.3 0.004 16.8 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RUS81351.1 - 0.014 15.3 0.1 0.032 14.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RUS81351.1 - 0.014 14.7 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS81351.1 - 0.031 13.2 1.5 0.11 11.4 0.1 2.3 3 0 0 3 3 3 0 Haspin like kinase domain DUF5588 PF17826.1 RUS81351.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) CLIP_SPH_Scar PF18399.1 RUS81354.1 - 0.00048 20.2 7.3 0.57 10.3 0.0 3.5 2 1 1 3 3 3 3 Clip-domain serine protease homolog Scarface Chorismate_synt PF01264.21 RUS81355.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Chorismate synthase DM PF00751.18 RUS81356.1 - 2.7e-23 81.6 10.7 4.5e-23 80.9 10.7 1.3 1 0 0 1 1 1 1 DM DNA binding domain Anp1 PF03452.14 RUS81356.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Anp1 TPR_1 PF00515.28 RUS81357.1 - 4.1e-07 29.5 0.8 0.25 11.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat preATP-grasp_3 PF18301.1 RUS81357.1 - 2.3e-05 24.5 0.0 5.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 pre ATP-grasp 3 domain TPR_2 PF07719.17 RUS81357.1 - 0.0015 18.5 0.4 1.9 8.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS81357.1 - 0.026 14.6 0.8 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RUS81357.1 - 0.089 13.0 1.1 0.26 11.6 1.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 D5_N PF08706.11 RUS81357.1 - 0.53 10.5 5.8 0.19 12.0 0.6 2.7 1 1 1 2 2 2 0 D5 N terminal like Cupin_8 PF13621.6 RUS81358.1 - 1.9e-36 126.1 0.1 2.6e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RUS81358.1 - 3.9e-07 29.9 0.3 6e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Nop14 PF04147.12 RUS81359.1 - 0.0027 16.0 13.6 0.0033 15.7 13.6 1.2 1 0 0 1 1 1 1 Nop14-like family FYDLN_acid PF09538.10 RUS81359.1 - 0.016 15.9 20.4 0.016 15.9 20.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3295 PF11702.8 RUS81359.1 - 0.022 14.1 11.8 0.03 13.7 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) BUD22 PF09073.10 RUS81359.1 - 0.045 13.1 10.7 0.07 12.5 10.7 1.4 1 0 0 1 1 1 0 BUD22 HTH_IclR PF09339.10 RUS81359.1 - 0.053 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_ner PF04546.13 RUS81359.1 - 0.091 12.6 11.3 0.15 11.9 11.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region SAPS PF04499.15 RUS81359.1 - 0.52 9.0 3.2 0.47 9.2 3.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RUS81359.1 - 1.2 7.3 18.8 1.8 6.7 18.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RUS81359.1 - 1.6 8.5 12.3 0.14 11.8 7.7 1.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 RUS81359.1 - 6.5 6.0 35.3 2.8 7.2 32.8 1.6 2 0 0 2 2 2 0 NOA36 protein SDA1 PF05285.12 RUS81359.1 - 8 5.8 24.6 0.61 9.5 20.1 1.4 2 0 0 2 2 2 0 SDA1 DUF2457 PF10446.9 RUS81359.1 - 8.4 5.4 45.0 14 4.6 45.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FYVE PF01363.21 RUS81360.1 - 2.9e-17 62.5 14.4 4.9e-17 61.8 14.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 RUS81360.1 - 0.0002 21.3 4.0 0.18 11.9 0.0 3.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat NdhN PF11909.8 RUS81360.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Peptidase_M28 PF04389.17 RUS81361.1 - 6.8e-31 107.5 0.0 6.3e-15 55.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M28 DUF295 PF03478.18 RUS81361.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) SRF-TF PF00319.18 RUS81362.1 - 7.3e-21 73.4 0.1 1.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dak1 PF02733.17 RUS81363.1 - 2.5e-112 374.8 5.5 3.6e-112 374.3 5.5 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 RUS81363.1 - 1.2e-42 145.8 7.7 1.2e-42 145.8 7.7 2.1 2 0 0 2 2 2 1 DAK2 domain EF-hand_7 PF13499.6 RUS81364.1 - 3e-18 66.0 4.6 3.5e-14 53.0 2.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS81364.1 - 5.7e-13 47.7 4.6 1.4e-06 27.7 0.3 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RUS81364.1 - 1.4e-12 46.2 9.6 4.1e-06 25.9 0.6 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 RUS81364.1 - 2.1e-07 30.7 1.5 0.0045 16.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS81364.1 - 3.3e-07 29.5 3.5 0.00013 21.3 0.2 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 RUS81364.1 - 1.9e-05 25.0 1.2 0.00019 21.7 0.6 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS81364.1 - 0.0021 18.0 2.8 0.0098 15.8 2.2 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand T6SS_VipA PF05591.12 RUS81364.1 - 0.17 11.7 3.5 0.37 10.6 0.8 2.1 1 1 1 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Sec23_trunk PF04811.15 RUS81365.1 - 8e-79 264.6 0.0 1.2e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 RUS81365.1 - 2.8e-33 114.5 0.0 9.2e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 RUS81365.1 - 3.1e-24 84.8 0.8 6.1e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 RUS81365.1 - 3e-16 59.2 9.8 5.4e-16 58.4 9.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RUS81365.1 - 1.8e-14 53.4 0.2 1e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Mab-21 PF03281.14 RUS81366.1 - 2.9e-43 148.3 0.0 3.7e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein IMUP PF15761.5 RUS81366.1 - 0.032 14.9 7.2 0.051 14.3 7.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 RUS81366.1 - 0.51 9.9 10.5 0.77 9.3 10.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 RUS81366.1 - 3.9 5.6 5.7 5.6 5.1 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sugar_tr PF00083.24 RUS81367.1 - 0.00031 19.7 0.4 0.00036 19.5 0.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS81367.1 - 0.00061 18.8 1.7 0.00066 18.7 1.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS81368.1 - 4.3e-06 25.9 13.5 4.3e-06 25.9 13.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos_2 PF14529.6 RUS81369.1 - 3.2e-05 23.7 0.1 5.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS81369.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family S8_pro-domain PF16470.5 RUS81370.1 - 4.2e-20 72.3 0.2 5.3e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF3450 PF11932.8 RUS81371.1 - 0.0005 19.4 3.3 0.0008 18.8 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TelA PF05816.11 RUS81371.1 - 0.00097 18.3 1.8 0.0015 17.7 1.8 1.4 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF4618 PF15397.6 RUS81371.1 - 0.0021 17.5 7.6 0.0021 17.5 7.6 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) GldM_N PF12081.8 RUS81371.1 - 0.0043 17.2 4.6 0.0065 16.6 4.6 1.3 1 0 0 1 1 1 1 GldM N-terminal domain Fez1 PF06818.15 RUS81371.1 - 0.013 16.0 7.3 0.021 15.3 7.3 1.4 1 0 0 1 1 1 0 Fez1 FAP206 PF12018.8 RUS81371.1 - 0.014 14.9 0.7 0.019 14.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function CENP-Q PF13094.6 RUS81371.1 - 0.017 15.3 7.0 0.042 14.1 6.5 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 RUS81371.1 - 0.044 12.7 8.1 0.065 12.1 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 RUS81371.1 - 0.066 12.5 5.4 0.1 11.9 5.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein YojJ PF10372.9 RUS81371.1 - 0.11 12.6 1.9 0.3 11.2 1.9 1.8 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Atg14 PF10186.9 RUS81371.1 - 0.13 11.3 7.6 0.2 10.7 7.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2205 PF10224.9 RUS81371.1 - 0.17 11.9 5.9 0.36 10.8 4.7 2.2 2 1 0 2 2 2 0 Short coiled-coil protein Fib_alpha PF08702.10 RUS81371.1 - 0.18 12.0 8.0 0.39 10.9 8.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 RUS81371.1 - 0.22 9.5 2.5 0.27 9.1 2.5 1.1 1 0 0 1 1 1 0 Prominin YabA PF06156.13 RUS81371.1 - 0.41 11.3 9.9 1.6 9.4 9.9 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DivIVA PF05103.13 RUS81371.1 - 0.46 10.6 9.7 0.44 10.6 7.7 1.9 1 1 1 2 2 2 0 DivIVA protein DUF1664 PF07889.12 RUS81371.1 - 0.5 10.4 8.9 0.094 12.8 5.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 RUS81371.1 - 0.91 9.1 4.8 0.82 9.2 2.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 RUS81371.1 - 2.2 8.8 8.2 4.5 7.8 7.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 RUS81371.1 - 2.3 8.7 11.2 0.66 10.5 6.7 2.3 1 1 1 2 2 2 0 Cell division protein ZapB zf-H2C2_2 PF13465.6 RUS81372.1 - 1.8e-40 135.6 48.9 1.1e-06 28.7 0.3 7.9 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 RUS81372.1 - 4.5e-35 118.2 52.9 1e-05 25.7 0.8 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS81372.1 - 4.3e-29 98.7 49.7 0.00067 20.3 1.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 RUS81372.1 - 3.2e-12 46.4 32.9 0.043 14.2 0.4 7.4 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS81372.1 - 1.3e-10 41.0 50.6 0.017 15.1 1.3 8.7 8 1 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS81372.1 - 2e-10 40.7 25.1 0.22 11.8 0.0 6.7 7 0 0 7 7 6 5 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RUS81372.1 - 1.3e-07 31.4 29.2 0.036 14.0 0.0 7.9 8 0 0 8 8 8 3 zinc-finger of a C2HC-type BolA PF01722.18 RUS81372.1 - 0.0033 17.7 1.4 12 6.3 0.2 3.7 2 1 0 2 2 2 0 BolA-like protein C1_4 PF07975.12 RUS81372.1 - 0.0036 17.5 33.3 4.6 7.6 0.8 6.2 1 1 6 7 7 7 4 TFIIH C1-like domain DUF3268 PF11672.8 RUS81372.1 - 0.064 13.6 22.1 0.15 12.4 1.8 4.0 2 2 3 5 5 5 0 zinc-finger-containing domain DUF3850 PF12961.7 RUS81372.1 - 0.1 12.7 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) zf_UBZ PF18439.1 RUS81372.1 - 0.14 11.8 21.5 13 5.5 0.0 7.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS81372.1 - 0.17 12.1 29.7 0.21 11.7 1.3 6.0 1 1 5 6 6 6 0 Zinc ribbon domain C1_2 PF03107.16 RUS81372.1 - 0.25 11.7 41.3 0.97 9.8 2.8 7.1 1 1 3 4 4 3 0 C1 domain C1-set PF07654.15 RUS81372.1 - 0.26 11.7 4.1 61 4.1 0.0 3.8 1 1 3 4 4 4 0 Immunoglobulin C1-set domain zinc_ribbon_15 PF17032.5 RUS81372.1 - 0.44 11.3 22.9 0.42 11.4 0.4 4.1 1 1 4 5 5 5 0 zinc-ribbon family Elf1 PF05129.13 RUS81372.1 - 0.46 10.6 26.6 0.1 12.7 0.9 4.2 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like zf-MYST PF17772.1 RUS81372.1 - 0.73 9.5 16.2 20 4.9 0.1 6.3 5 2 2 7 7 7 0 MYST family zinc finger domain zf-AN1 PF01428.16 RUS81372.1 - 0.77 10.0 33.6 11 6.2 0.2 7.3 5 1 2 7 7 7 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 RUS81372.1 - 1.2 9.0 0.0 1.2 9.0 0.0 7.4 7 1 0 7 7 7 0 C2H2-type zinc-finger domain Endostatin PF06482.11 RUS81373.1 - 6.7e-81 272.2 0.0 1.8e-69 234.6 0.1 2.0 1 1 1 2 2 2 2 Collagenase NC10 and Endostatin Collagen PF01391.18 RUS81373.1 - 1.8e-15 56.4 93.6 5.9e-06 25.9 23.1 4.4 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) DUF1554 PF07588.11 RUS81373.1 - 9.6e-05 22.2 0.4 0.00031 20.5 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) Collagen PF01391.18 RUS81374.1 - 1.3e-74 245.8 313.9 5.7e-10 38.8 25.4 12.3 6 3 5 11 11 11 11 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.6 RUS81375.1 - 0.00033 20.8 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 RUS81375.1 - 0.026 15.1 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Collagen PF01391.18 RUS81375.1 - 0.2 11.5 16.5 0.081 12.7 7.8 2.9 3 1 0 3 3 3 0 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 RUS81376.1 - 0.0037 18.0 4.5 0.049 14.4 1.4 2.1 2 0 0 2 2 2 2 Lectin C-type domain Ig_3 PF13927.6 RUS81377.1 - 0.00099 19.7 1.2 0.057 14.0 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin domain Lectin_C PF00059.21 RUS81377.1 - 0.0073 17.0 0.8 0.018 15.8 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain Ig_2 PF13895.6 RUS81377.1 - 0.023 15.0 0.2 0.17 12.3 0.1 2.4 2 1 1 3 3 3 0 Immunoglobulin domain Dimer_Tnp_hAT PF05699.14 RUS81379.1 - 1.5e-05 24.7 0.1 3.2e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3540 PF12059.8 RUS81381.1 - 0.00031 20.6 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3540) DUF4786 PF16027.5 RUS81381.1 - 1.1 9.8 4.1 16 6.0 4.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4786) UPF0300 PF08594.10 RUS81381.1 - 3.2 7.0 8.1 11 5.2 0.7 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0300) DUF2990 PF11693.8 RUS81382.1 - 0.035 14.3 1.3 5.2 7.3 0.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2990) Neur_chan_LBD PF02931.23 RUS81384.1 - 2.1e-28 99.3 5.1 6.9e-23 81.2 3.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS81384.1 - 2.1e-22 80.4 15.7 1.4e-21 77.7 6.9 2.4 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region SPC25 PF06703.11 RUS81384.1 - 0.11 12.3 0.2 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2417 PF10329.9 RUS81384.1 - 1.1 8.6 12.4 0.56 9.6 5.4 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF1706 PF08020.11 RUS81384.1 - 2 8.3 7.2 1 9.2 3.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) Peptidase_M13_N PF05649.13 RUS81385.1 - 2.5e-20 73.5 0.0 4.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS81385.1 - 1.2e-16 61.0 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 IgGFc_binding PF17517.2 RUS81386.1 - 9.4e-11 41.5 0.0 5.5e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 IgGFc binding protein Patatin PF01734.22 RUS81387.1 - 1e-15 58.5 0.0 1.4e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase CARMIL_C PF16000.5 RUS81388.1 - 4.8e-35 121.7 7.7 4.8e-35 121.7 7.7 5.7 3 3 2 5 5 5 1 CARMIL C-terminus Carm_PH PF17888.1 RUS81388.1 - 9.7e-30 102.8 0.2 2.4e-29 101.5 0.2 1.7 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 RUS81388.1 - 0.00013 21.7 21.6 0.013 15.5 0.2 8.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 RUS81388.1 - 1.3 9.6 30.1 1 9.9 0.1 7.6 7 1 2 9 9 9 0 Leucine Rich repeats (2 copies) Fzo_mitofusin PF04799.13 RUS81388.1 - 8.1 6.0 6.7 10 5.6 0.3 2.4 2 0 0 2 2 2 0 fzo-like conserved region GHD PF17834.1 RUS81389.1 - 4.2 7.5 6.7 0.32 11.1 1.2 2.0 3 0 0 3 3 3 0 Beta-sandwich domain in beta galactosidase CMD PF02627.20 RUS81390.1 - 0.062 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Folate_carrier PF01770.18 RUS81390.1 - 0.23 10.2 0.3 0.34 9.6 0.3 1.3 1 0 0 1 1 1 0 Reduced folate carrier RNA_pol_Rpc4 PF05132.14 RUS81390.1 - 0.27 11.7 8.3 0.36 11.2 8.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFIIA PF03153.13 RUS81390.1 - 0.36 10.8 17.4 0.39 10.6 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.6 RUS81390.1 - 0.59 8.8 9.4 0.69 8.6 9.4 1.1 1 0 0 1 1 1 0 Raftlin Connexin PF00029.19 RUS81390.1 - 0.63 9.8 9.6 0.92 9.2 9.6 1.3 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 RUS81390.1 - 0.79 9.1 14.1 0.95 8.9 14.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 RUS81390.1 - 1.4 7.0 37.0 1.7 6.8 37.0 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 RUS81390.1 - 1.6 8.8 6.3 2.2 8.4 6.3 1.2 1 0 0 1 1 1 0 DDHD domain SDA1 PF05285.12 RUS81390.1 - 2.1 7.7 45.0 2.6 7.4 45.0 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS81390.1 - 4.1 5.7 36.3 5.1 5.4 36.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 RUS81390.1 - 4.2 6.2 12.7 5.4 5.9 12.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 RUS81390.1 - 4.5 6.8 31.6 6 6.4 31.6 1.2 1 0 0 1 1 1 0 PPP4R2 RAB3GAP2_C PF14656.6 RUS81390.1 - 5.9 5.0 8.2 7 4.8 8.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus BAMBI PF06211.12 RUS81391.1 - 1.8e-12 47.5 10.4 1.8e-12 47.5 10.4 3.5 2 2 1 3 3 3 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Macin PF14865.6 RUS81392.1 - 8.9e-11 42.2 12.6 1.2e-10 41.8 12.6 1.1 1 0 0 1 1 1 1 Macin Gamma-thionin PF00304.20 RUS81392.1 - 1.9 8.8 16.2 1.1 9.5 10.6 2.6 1 1 1 2 2 2 0 Gamma-thionin family Defensin_like PF10868.8 RUS81392.1 - 1.9 9.3 14.1 24 5.8 14.1 2.4 1 1 0 1 1 1 0 Cysteine-rich antifungal protein 2, defensin-like Homeodomain PF00046.29 RUS81393.1 - 6.8e-23 80.3 4.3 1.2e-22 79.5 4.3 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS81393.1 - 2.3e-06 27.2 2.6 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 OAR domain Enkurin PF13864.6 RUS81395.1 - 3.5e-30 104.3 5.3 3.5e-30 104.3 5.3 2.0 3 0 0 3 3 3 1 Calmodulin-binding Gluconate_2-dh3 PF13618.6 RUS81395.1 - 0.18 12.0 1.0 0.4 10.9 0.3 1.8 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 HMG_box PF00505.19 RUS81396.1 - 1.5e-13 50.9 7.9 1.5e-13 50.9 7.9 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS81396.1 - 1.7e-09 38.1 4.5 1.7e-09 38.1 4.5 1.9 2 0 0 2 2 2 1 HMG-box domain DivIC PF04977.15 RUS81396.1 - 0.0083 15.9 4.0 0.013 15.2 1.9 2.3 1 1 1 2 2 2 1 Septum formation initiator HAUS2 PF15003.6 RUS81396.1 - 0.04 13.7 2.3 0.05 13.3 1.4 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 TMPIT PF07851.13 RUS81396.1 - 0.1 11.8 3.7 0.088 12.0 2.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein CENP-H PF05837.12 RUS81396.1 - 0.18 12.3 3.2 8.6 6.8 0.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2205 PF10224.9 RUS81396.1 - 0.25 11.4 3.0 0.17 11.9 0.7 2.0 2 0 0 2 2 2 0 Short coiled-coil protein HMG_box_5 PF14887.6 RUS81396.1 - 0.72 9.9 6.0 0.57 10.2 0.4 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 TPR_19 PF14559.6 RUS81397.1 - 2.3e-13 50.4 1.0 7.1e-05 23.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS81397.1 - 8.2e-12 44.3 10.7 0.086 13.0 0.5 7.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS81397.1 - 7.4e-11 41.4 10.9 0.0076 16.0 0.6 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS81397.1 - 7.6e-11 41.5 0.7 0.0026 17.4 0.0 5.6 6 0 0 6 6 6 2 TPR repeat TPR_17 PF13431.6 RUS81397.1 - 3e-10 39.7 1.8 0.015 15.6 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS81397.1 - 3.1e-09 36.3 18.6 0.033 14.4 0.0 7.7 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 RUS81397.1 - 1.7e-07 31.3 0.0 4.9e-05 23.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS81397.1 - 2.7e-07 30.9 4.3 0.48 11.4 0.0 5.4 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81397.1 - 3.5e-06 27.5 0.0 0.093 13.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS81397.1 - 1.4e-05 25.1 5.5 0.066 13.3 0.1 5.1 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RUS81397.1 - 6.9e-05 23.0 1.1 0.63 10.3 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 RUS81397.1 - 7.6e-05 23.2 4.7 0.0016 18.9 0.1 3.5 3 2 0 3 3 3 1 Alkyl sulfatase dimerisation ChAPs PF09295.10 RUS81397.1 - 0.0018 17.3 0.4 1.3 7.9 0.0 2.5 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 RUS81397.1 - 0.0037 17.2 5.6 1.8 8.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 RUS81397.1 - 0.0045 17.4 1.2 2.1 8.7 0.2 2.9 2 2 0 2 2 2 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 RUS81397.1 - 0.088 12.2 0.6 0.33 10.3 0.2 2.2 2 1 0 2 2 2 0 MalT-like TPR region TPR_12 PF13424.6 RUS81397.1 - 0.3 11.4 9.9 0.49 10.7 0.1 4.3 5 1 1 6 6 5 0 Tetratricopeptide repeat Pkinase PF00069.25 RUS81398.1 - 2.1e-40 138.8 0.0 2.6e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81398.1 - 1.9e-20 73.2 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS81398.1 - 0.00067 19.7 0.1 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS81398.1 - 0.0062 15.9 0.0 0.032 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like JMY PF15871.5 RUS81399.1 - 1.4e-40 139.7 17.5 1.4e-40 139.7 17.5 2.8 2 1 0 2 2 2 1 Junction-mediating and -regulatory protein WHAMM-JMY_N PF15920.5 RUS81399.1 - 3.2e-05 23.7 1.0 7e-05 22.6 1.0 1.5 1 0 0 1 1 1 1 N-terminal of Junction-mediating and WASP homolog-associated CAP_N PF01213.19 RUS81400.1 - 0.033 13.7 20.5 0.15 11.5 20.5 2.0 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 RUS81401.1 - 4e-52 173.9 0.1 2.7e-17 62.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS81401.1 - 3.3e-07 30.3 0.5 0.037 14.1 0.2 2.5 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 RUS81401.1 - 0.012 15.7 0.5 4.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.6 RUS81401.1 - 0.035 14.1 0.0 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF4875 PF16175.5 RUS81401.1 - 0.1 12.8 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) zf-LYAR PF08790.11 RUS81402.1 - 1.5e-15 56.7 7.4 2.7e-15 55.9 2.4 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger VPR PF00522.18 RUS81402.1 - 0.009 16.0 2.4 0.12 12.4 0.0 3.0 2 1 1 3 3 3 1 VPR/VPX protein IBR PF01485.21 RUS81402.1 - 0.52 10.6 10.5 0.65 10.3 8.6 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-ACC PF17848.1 RUS81402.1 - 1.7 8.8 10.7 0.058 13.5 3.7 2.4 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-B_box PF00643.24 RUS81402.1 - 2.4 8.4 10.5 2.8 8.1 8.5 2.2 1 1 1 2 2 2 0 B-box zinc finger Hid1 PF12722.7 RUS81402.1 - 5.8 4.9 16.6 7.3 4.6 16.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein C1_2 PF03107.16 RUS81402.1 - 6.7 7.1 8.9 1.9 8.9 5.7 1.8 2 0 0 2 2 2 0 C1 domain Dynactin PF12455.8 RUS81403.1 - 1.8e-76 257.1 8.8 1.8e-76 257.1 8.8 4.6 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 RUS81403.1 - 3.8e-21 74.9 2.4 6.3e-21 74.2 2.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.6 RUS81403.1 - 0.0012 18.2 34.0 0.0012 18.2 34.0 5.6 3 1 3 6 6 6 3 Growth-arrest specific micro-tubule binding HTH_19 PF12844.7 RUS81403.1 - 3.4 7.8 10.5 1.4 9.0 1.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Sec15 PF04091.12 RUS81404.1 - 4.5e-94 315.4 5.5 1e-93 314.2 5.5 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Zw10 PF06248.13 RUS81404.1 - 4.9e-05 22.1 0.6 4.9e-05 22.1 0.6 2.0 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Sec8_exocyst PF04048.14 RUS81404.1 - 0.0047 16.8 0.1 0.0047 16.8 0.1 2.9 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 RUS81404.1 - 0.015 15.4 13.6 0.019 15.1 0.1 4.8 4 1 1 5 5 5 0 Golgi transport complex subunit 5 TPR_8 PF13181.6 RUS81404.1 - 5 7.6 4.9 38 4.8 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Thg1 PF04446.12 RUS81405.1 - 5e-51 171.9 0.2 7.7e-51 171.3 0.2 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 RUS81405.1 - 2e-44 150.7 0.0 3e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain DUF4506 PF14958.6 RUS81406.1 - 6.2e-20 71.2 0.3 3e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) Apolipoprotein PF01442.18 RUS81406.1 - 0.004 17.0 2.2 0.018 14.9 1.2 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1690 PF07956.11 RUS81406.1 - 0.068 13.6 2.9 0.34 11.3 1.6 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) YtxH PF12732.7 RUS81406.1 - 0.099 13.2 1.7 4.9 7.8 0.2 2.4 2 0 0 2 2 2 0 YtxH-like protein HlyD_2 PF12700.7 RUS81406.1 - 0.12 11.0 2.2 0.093 11.4 0.5 1.6 2 0 0 2 2 2 0 HlyD family secretion protein DUF948 PF06103.11 RUS81406.1 - 0.13 12.5 2.3 0.19 12.0 1.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RUS81406.1 - 0.14 12.2 5.7 1.4 9.0 2.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PH_17 PF18012.1 RUS81406.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 PH domain HSCB_C PF07743.13 RUS81406.1 - 0.19 12.2 1.9 0.4 11.2 0.7 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Disulph_isomer PF06491.11 RUS81406.1 - 0.43 10.7 2.8 2.7 8.1 0.1 2.7 3 0 0 3 3 3 0 Disulphide isomerase Forkhead_N PF08430.12 RUS81406.1 - 2.4 8.8 9.8 1.8 9.1 7.6 1.8 2 1 0 2 2 2 0 Forkhead N-terminal region WD40 PF00400.32 RUS81407.1 - 3e-08 34.2 7.4 0.12 13.3 0.1 6.6 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS81407.1 - 9e-05 22.7 0.0 13 6.2 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 RUS81407.1 - 0.021 14.6 0.0 5.3 6.7 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split baeRF_family7 PF18849.1 RUS81407.1 - 0.043 14.0 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 SCAB-PH PF17684.1 RUS81407.1 - 0.044 14.0 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein DUF4394 PF14339.6 RUS81407.1 - 0.053 12.9 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) DUF842 PF05811.13 RUS81408.1 - 1.4e-45 154.2 16.3 1.5e-45 154.1 16.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) RasGAP_C PF03836.15 RUS81408.1 - 0.023 14.8 0.2 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 RasGAP C-terminus ApoLp-III PF07464.11 RUS81408.1 - 0.025 14.7 0.9 6.1e+02 0.4 0.0 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 RUS81408.1 - 0.026 14.6 0.1 0.057 13.5 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 RUS81408.1 - 0.031 14.6 0.4 0.054 13.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF5481 PF17578.2 RUS81408.1 - 0.037 14.4 1.7 0.058 13.8 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5481) PriC PF07445.12 RUS81408.1 - 0.048 13.6 5.3 0.062 13.2 5.3 1.2 1 0 0 1 1 1 0 Primosomal replication protein priC Muted PF14942.6 RUS81408.1 - 0.091 13.1 1.6 0.13 12.6 1.6 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FAS_I_H PF18314.1 RUS81408.1 - 0.099 12.3 0.7 0.12 12.0 0.7 1.3 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Vicilin_N PF04702.12 RUS81408.1 - 0.1 12.4 10.8 0.15 11.9 10.8 1.3 1 0 0 1 1 1 0 Vicilin N terminal region Integrin_alpha2 PF08441.12 RUS81409.1 - 1.1e-79 268.5 0.4 1.3e-79 268.2 0.4 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 RUS81409.1 - 9.1e-22 76.9 13.4 1.2e-09 38.1 1.9 4.6 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 RUS81409.1 - 2.7e-08 34.3 3.9 0.0031 18.0 0.1 3.8 4 1 1 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 RUS81409.1 - 0.012 15.3 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 RUS81409.1 - 0.082 12.9 1.7 0.18 11.8 1.7 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region DUF4381 PF14316.6 RUS81409.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HisK_sensor PF18698.1 RUS81409.1 - 0.11 12.9 0.7 9.6 6.6 0.1 3.0 3 0 0 3 3 3 0 Histidine kinase sensor domain Pox_EPC_I2-L1 PF12575.8 RUS81409.1 - 3.6 7.9 4.8 2.9 8.2 1.5 2.6 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 GCN5L1 PF06320.13 RUS81410.1 - 1.8e-46 157.0 8.7 2e-46 156.8 8.7 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) GSCFA PF08885.11 RUS81410.1 - 0.0029 17.3 1.5 0.0033 17.1 1.5 1.1 1 0 0 1 1 1 1 GSCFA family DUF390 PF04094.14 RUS81410.1 - 0.07 11.4 0.7 0.064 11.5 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) EF-hand_1 PF00036.32 RUS81411.1 - 2.6e-11 42.2 0.0 1.6e-06 27.2 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 RUS81411.1 - 3.7e-11 43.3 0.0 8.2e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS81411.1 - 2e-10 40.3 0.6 9.3e-09 35.0 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS81411.1 - 4.9e-06 26.0 0.0 0.37 10.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 RUS81411.1 - 0.0011 18.3 0.0 0.0038 16.7 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.6 RUS81411.1 - 0.066 13.5 0.1 2.1 8.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Mago-bind PF09282.10 RUS81412.1 - 7.2e-14 51.4 0.2 1.3e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 Mago binding AAA_23 PF13476.6 RUS81412.1 - 0.15 12.6 17.4 0.18 12.3 17.4 1.3 1 0 0 1 1 1 0 AAA domain NABP PF07990.12 RUS81412.1 - 0.21 11.1 6.8 0.27 10.7 6.8 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP SLX9 PF15341.6 RUS81412.1 - 0.34 11.3 24.4 1.3 9.4 18.9 2.2 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Baculo_F PF12259.8 RUS81412.1 - 3.3 6.1 8.5 3.8 5.9 8.5 1.0 1 0 0 1 1 1 0 Baculovirus F protein D123 PF07065.14 RUS81413.1 - 4.3e-24 85.2 2.1 9.8e-23 80.8 0.7 2.7 3 0 0 3 3 3 2 D123 R2K_2 PF18299.1 RUS81413.1 - 0.0016 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 DUF1647 PF07801.11 RUS81415.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) HA2 PF04408.23 RUS81416.1 - 3.5e-16 59.4 0.0 3.5e-16 59.4 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS81416.1 - 1.5e-15 57.3 0.0 4.4e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS81416.1 - 4.5e-11 43.1 1.6 1.3e-09 38.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS81416.1 - 3.7e-07 30.1 2.2 3.8e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS81416.1 - 2.2e-05 24.8 0.3 7.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS81416.1 - 5.4e-05 23.6 0.0 0.00022 21.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS81416.1 - 0.00042 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RUS81416.1 - 0.0031 16.8 0.0 0.0084 15.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 RUS81416.1 - 0.0034 16.8 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 RUS81416.1 - 0.017 15.6 18.6 0.074 13.6 0.0 3.6 3 1 1 4 4 4 0 AAA domain T2SSE PF00437.20 RUS81416.1 - 0.031 13.3 0.0 0.086 11.9 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 RUS81416.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 RUS81416.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RUS81416.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 RUS81416.1 - 0.46 11.0 6.0 0.58 10.7 0.0 3.3 3 1 0 3 3 3 0 ABC transporter Peptidase_S49_N PF08496.10 RUS81416.1 - 2.1 8.4 15.5 3.1 7.8 0.4 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal ResIII PF04851.15 RUS81416.1 - 3.8 7.5 11.2 0.33 11.0 0.1 3.6 3 2 0 3 3 3 0 Type III restriction enzyme, res subunit Abhydrolase_1 PF00561.20 RUS81417.1 - 7.4e-14 52.0 0.0 1.7e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS81417.1 - 1.1e-10 41.2 0.0 2.3e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS81417.1 - 0.00021 21.9 0.0 0.00071 20.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 RUS81417.1 - 0.0023 17.3 0.0 0.0064 15.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Spt4 PF06093.13 RUS81418.1 - 9.5e-34 115.3 1.6 1.1e-33 115.1 1.6 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger P2X_receptor PF00864.19 RUS81419.1 - 1.3e-137 458.8 0.1 1.5e-137 458.6 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.21 RUS81419.1 - 0.35 11.3 1.6 1.2 9.6 1.2 2.1 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ERM PF00769.19 RUS81420.1 - 2.7e-65 220.6 30.6 2.7e-65 220.6 30.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 RUS81420.1 - 1.6e-24 86.1 0.5 7.2e-24 84.0 0.0 2.3 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS81420.1 - 4e-23 82.0 0.5 4e-23 82.0 0.5 2.8 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.10 RUS81420.1 - 9.1e-15 54.4 2.8 1.1e-13 50.9 0.1 2.9 3 0 0 3 3 3 1 FERM N-terminal domain ACBP PF00887.19 RUS81420.1 - 0.013 15.7 0.1 0.013 15.7 0.1 2.2 2 0 0 2 2 2 0 Acyl CoA binding protein zf-Tim10_DDP PF02953.15 RUS81421.1 - 3e-16 58.8 1.0 3e-16 58.8 1.0 2.9 3 0 0 3 3 3 2 Tim10/DDP family zinc finger zf-TRAF PF02176.18 RUS81422.1 - 3e-05 24.6 6.2 3e-05 24.6 6.2 4.7 4 1 1 5 5 5 2 TRAF-type zinc finger XAF1_C PF18608.1 RUS81422.1 - 0.36 10.4 6.4 1.2 8.8 0.1 3.4 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain DUF872 PF05915.12 RUS81423.1 - 3.4e-31 107.8 0.1 3.8e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Amastin PF07344.11 RUS81423.1 - 0.021 14.7 0.2 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein Virul_fac_BrkB PF03631.15 RUS81423.1 - 0.034 13.7 0.6 0.05 13.2 0.6 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF3040 PF11239.8 RUS81423.1 - 0.05 13.9 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PGPGW PF09656.10 RUS81423.1 - 0.17 11.4 6.5 0.25 10.9 6.5 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) DUF2054 PF10218.9 RUS81424.1 - 8e-40 136.0 21.4 1e-39 135.7 21.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) DUF1712 PF08217.11 RUS81426.1 - 6.3e-10 38.2 0.2 6.3e-10 38.2 0.2 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) CLU PF13236.6 RUS81427.1 - 2.1e-89 299.1 0.0 4e-89 298.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 RUS81427.1 - 3.1e-56 190.2 1.0 1.2e-55 188.3 0.2 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 RUS81427.1 - 1.4e-23 83.0 10.8 1e-13 51.4 0.9 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 RUS81427.1 - 9.6e-16 57.1 6.8 5e-06 26.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 RUS81427.1 - 1.3e-15 57.5 0.0 3.6e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 RUS81427.1 - 1.9e-06 27.9 0.0 8.6e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_MalT PF17874.1 RUS81427.1 - 2.1e-06 27.3 2.3 1.9e-05 24.2 0.4 2.2 1 1 0 2 2 2 1 MalT-like TPR region TPR_2 PF07719.17 RUS81427.1 - 0.021 14.9 4.0 6.5 7.1 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS81427.1 - 0.18 11.9 1.0 18 5.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS81427.1 - 0.33 10.8 2.0 0.69 9.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_10 PF05971.12 RUS81428.1 - 1e-78 264.7 0.0 1.4e-78 264.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 RUS81428.1 - 2.2e-06 27.3 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RUS81428.1 - 0.00083 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) IF-2B PF01008.17 RUS81429.1 - 5.9e-72 242.2 0.7 6.8e-72 242.0 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family VKOR PF07884.14 RUS81430.1 - 1.8e-22 79.8 12.4 2.5e-22 79.3 12.4 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF2418 PF10332.9 RUS81430.1 - 4.3 7.9 5.7 1.2 9.7 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Pkinase PF00069.25 RUS81431.1 - 7.7e-62 209.0 0.6 4.5e-61 206.5 0.1 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81431.1 - 1.7e-25 89.8 0.0 4.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS81431.1 - 0.0024 17.3 0.1 0.0064 15.9 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MamL-1 PF09596.10 RUS81432.1 - 0.037 14.3 1.1 0.16 12.2 1.1 2.1 1 0 0 1 1 1 0 MamL-1 domain Mpv17_PMP22 PF04117.12 RUS81433.1 - 4e-18 65.4 2.9 7.6e-18 64.5 2.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lectin_C PF00059.21 RUS81434.1 - 1.5e-15 57.9 2.4 3e-09 37.6 0.2 4.1 4 0 0 4 4 4 3 Lectin C-type domain PAN_1 PF00024.26 RUS81434.1 - 1.1e-13 50.9 2.3 0.021 14.8 0.0 4.8 4 0 0 4 4 4 3 PAN domain PAN_4 PF14295.6 RUS81434.1 - 1.7e-06 27.8 30.1 0.0084 16.0 1.1 4.9 5 0 0 5 5 5 3 PAN domain Inp1 PF12634.7 RUS81434.1 - 0.12 12.4 0.1 1.2e+02 2.7 0.0 3.2 3 0 0 3 3 3 0 Inheritance of peroxisomes protein 1 MANEC PF07502.14 RUS81434.1 - 2 8.7 17.1 11 6.4 0.2 4.5 4 0 0 4 4 4 0 MANEC domain CDC45 PF02724.14 RUS81435.1 - 4e-142 474.7 14.2 1.1e-136 456.7 14.2 3.0 1 1 0 1 1 1 1 CDC45-like protein Hira PF07569.11 RUS81436.1 - 0.05 13.3 0.2 4.1 7.1 0.1 2.7 2 1 0 2 2 2 0 TUP1-like enhancer of split Branch PF02485.21 RUS81437.1 - 2.6e-12 46.8 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 RUS81438.1 - 4.1e-17 62.5 0.0 5.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RMMBL PF07521.12 RUS81438.1 - 0.085 12.8 0.1 1.5 8.8 0.1 2.8 2 1 1 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain RRM_1 PF00076.22 RUS81439.1 - 2.7e-11 43.1 0.0 8.3e-11 41.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 RUS81439.1 - 6.7e-07 28.5 5.2 9.4e-07 28.0 5.2 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ras PF00071.22 RUS81440.1 - 4.7e-26 91.3 0.0 8.8e-26 90.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS81440.1 - 2e-17 63.5 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81440.1 - 0.00016 21.2 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RUS81440.1 - 0.02 14.1 0.1 2.5 7.2 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 RUS81440.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS81440.1 - 0.03 14.2 0.0 0.59 10.0 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase DUF815 PF05673.13 RUS81440.1 - 0.043 13.0 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.13 RUS81440.1 - 0.047 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 RUS81440.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RUS81440.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 RUS81440.1 - 0.17 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain FXa_inhibition PF14670.6 RUS81441.1 - 0.00082 19.6 7.7 0.0014 18.9 7.7 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 RUS81442.1 - 3.3e-09 37.1 2.0 0.23 12.0 0.0 5.1 4 1 0 4 4 4 4 Low-density lipoprotein receptor repeat class B NHL PF01436.21 RUS81442.1 - 0.00082 19.3 0.0 0.017 15.1 0.0 3.0 3 0 0 3 3 3 1 NHL repeat EGF PF00008.27 RUS81442.1 - 0.014 15.6 6.1 0.025 14.9 6.1 1.3 1 0 0 1 1 1 0 EGF-like domain HYR PF02494.16 RUS81443.1 - 9.9e-22 77.1 3.7 2.4e-16 59.8 0.4 2.7 2 1 0 2 2 2 2 HYR domain Ephrin_rec_like PF07699.13 RUS81443.1 - 4e-09 36.1 3.1 4e-09 36.1 3.1 2.6 1 1 1 2 2 2 2 Putative ephrin-receptor like VSP PF03302.13 RUS81443.1 - 0.052 12.4 2.7 0.085 11.7 2.7 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein NCD3G PF07562.14 RUS81443.1 - 0.35 10.9 5.0 1.2 9.1 5.0 2.0 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF4215 PF13948.6 RUS81443.1 - 0.92 10.0 9.3 0.44 11.0 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) TNFR_c6 PF00020.18 RUS81443.1 - 3.2 8.2 5.0 4.9 7.6 0.2 2.7 1 1 2 3 3 3 0 TNFR/NGFR cysteine-rich region Ldl_recept_a PF00057.18 RUS81444.1 - 2.8e-07 30.6 7.5 7e-07 29.4 7.5 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 RUS81444.1 - 7.3e-06 26.3 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 CUB domain FMO-like PF00743.19 RUS81445.1 - 5.9e-60 203.2 0.0 7.2e-49 166.6 0.1 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS81445.1 - 3e-17 62.8 4.7 9.1e-13 48.1 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS81445.1 - 1.6e-07 30.9 0.1 9.8e-06 25.0 0.1 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS81445.1 - 3.1e-06 26.6 0.1 3.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 RUS81445.1 - 1.2e-05 25.3 0.1 0.039 13.9 0.1 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 RUS81445.1 - 0.0016 18.1 0.1 14 5.1 0.2 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RUS81445.1 - 0.031 14.5 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_S9 PF00326.21 RUS81445.1 - 0.13 11.7 0.4 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox PF00070.27 RUS81445.1 - 0.54 10.8 1.5 0.93 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Neur_chan_LBD PF02931.23 RUS81446.1 - 1.3e-68 230.6 3.2 1.8e-68 230.2 3.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS81446.1 - 7.2e-68 229.2 0.2 8.9e-68 228.9 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ydr279_N PF17745.1 RUS81446.1 - 0.02 15.2 0.2 0.04 14.2 0.2 1.4 1 0 0 1 1 1 0 Ydr279p protein triple barrel domain 7TMR-DISM_7TM PF07695.11 RUS81446.1 - 1.3 8.9 11.6 0.47 10.3 8.0 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling Neur_chan_memb PF02932.16 RUS81448.1 - 1.6e-87 293.5 0.0 2.1e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS81448.1 - 1.2e-74 250.4 1.0 1.6e-74 250.0 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1765 PF08578.10 RUS81448.1 - 0.056 13.9 0.8 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) AC_N PF16214.5 RUS81449.1 - 0.67 9.0 4.4 1.4 8.0 4.4 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Neur_chan_memb PF02932.16 RUS81450.1 - 1.8e-70 237.7 6.4 3.5e-70 236.8 6.4 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS81450.1 - 2.2e-59 200.5 1.1 3.1e-59 200.0 1.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 RUS81450.1 - 2.4 6.3 6.8 3.5 5.8 6.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CTC1 PF15489.6 RUS81451.1 - 3.1e-17 61.5 6.1 3.5e-17 61.3 6.1 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 CTC1 PF15489.6 RUS81452.1 - 3.2e-06 25.0 0.2 5.9e-06 24.1 0.0 1.4 2 0 0 2 2 2 1 CST, telomere maintenance, complex subunit CTC1 Pkinase PF00069.25 RUS81454.1 - 1.5e-72 244.1 0.0 2.3e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81454.1 - 2e-35 122.3 0.0 3.1e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS81454.1 - 8.5e-06 24.9 0.3 8.5e-06 24.9 0.3 2.3 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 RUS81454.1 - 0.0088 15.4 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like ADP_ribosyl_GH PF03747.14 RUS81455.1 - 6e-56 190.3 0.0 6.9e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Kri1 PF05178.12 RUS81455.1 - 0.045 14.3 0.6 0.16 12.6 0.1 2.0 2 0 0 2 2 2 0 KRI1-like family tRNA_NucTransf2 PF09249.11 RUS81455.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain RP1-2 PF12042.8 RUS81455.1 - 0.12 12.2 1.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain p450 PF00067.22 RUS81456.1 - 1.7e-24 86.4 0.0 1.9e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS81457.1 - 8.3e-50 169.9 0.2 9.1e-50 169.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_1 PF00001.21 RUS81458.1 - 3.7e-39 134.6 3.6 8.2e-25 87.6 2.5 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS81458.1 - 2.8e-07 30.4 0.4 5e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS81458.1 - 6.2e-06 26.1 2.2 5.9e-05 22.9 1.2 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS81458.1 - 0.0039 16.6 3.6 1 8.7 0.5 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_U4 PF03419.13 RUS81458.1 - 0.014 14.7 0.6 0.024 13.9 0.6 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA 7TM_GPCR_Srbc PF10316.9 RUS81458.1 - 0.085 12.4 3.0 0.69 9.4 3.0 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srv PF10323.9 RUS81458.1 - 0.32 10.3 3.6 0.2 11.0 0.7 2.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv VCBS PF13517.6 RUS81459.1 - 0.014 16.0 3.3 0.075 13.6 0.7 2.1 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF667 PF05018.13 RUS81460.1 - 7.8e-94 312.6 1.0 9.2e-94 312.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Fib_alpha PF08702.10 RUS81461.1 - 0.0033 17.6 11.4 0.0033 17.6 11.4 3.8 1 1 4 5 5 5 2 Fibrinogen alpha/beta chain family MAD PF05557.13 RUS81461.1 - 0.0048 15.3 50.1 0.0058 15.1 50.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein HsbA PF12296.8 RUS81461.1 - 0.045 14.2 3.6 0.15 12.5 0.7 2.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A P22_Tail-4 PF11650.8 RUS81461.1 - 0.09 12.7 1.7 0.26 11.2 1.7 1.8 1 0 0 1 1 1 0 P22 tail accessory factor T2SSF PF00482.23 RUS81461.1 - 8.9 6.3 8.1 4.2 7.3 3.4 2.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F JAB PF01398.21 RUS81462.1 - 6.3e-33 113.2 0.0 9.5e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RUS81462.1 - 8.1e-18 64.9 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PAPS_reduct PF01507.19 RUS81463.1 - 0.69 9.9 16.5 15 5.5 3.8 3.9 1 1 2 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Paramecium_SA PF01508.16 RUS81464.1 - 0.055 13.9 0.4 0.055 13.9 0.4 2.9 2 1 0 2 2 2 0 Paramecium surface antigen domain Disintegrin PF00200.23 RUS81465.1 - 7.7e-12 45.8 18.1 7.7e-12 45.8 18.1 3.6 3 1 0 3 3 3 1 Disintegrin ADAM17_MPD PF16698.5 RUS81465.1 - 6.1e-09 36.1 15.1 6.1e-09 36.1 15.1 3.6 2 1 1 3 3 3 1 Membrane-proximal domain, switch, for ADAM17 Reprolysin_5 PF13688.6 RUS81466.1 - 4.4e-16 59.6 0.0 5.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS81466.1 - 7.6e-14 52.1 0.1 1e-13 51.6 0.1 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS81466.1 - 5.3e-07 30.2 0.0 1e-06 29.3 0.0 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS81467.1 - 1.2e-05 25.6 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Reprolysin family propeptide Ntox11 PF15521.6 RUS81467.1 - 0.077 12.6 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Novel toxin 11 RVT_1 PF00078.27 RUS81468.1 - 0.046 13.2 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 RUS81469.1 - 1.4e-23 83.6 0.1 1.9e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ependymin PF00811.18 RUS81471.1 - 0.018 15.3 0.1 0.81 9.9 0.0 2.7 3 0 0 3 3 3 0 Ependymin YchF-GTPase_C PF06071.13 RUS81472.1 - 1e-39 134.6 1.3 2.4e-39 133.4 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RUS81472.1 - 6.4e-23 81.0 0.0 2.3e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS81472.1 - 2.5e-07 30.3 0.0 5.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 RUS81472.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain Roc PF08477.13 RUS81472.1 - 0.006 16.8 0.0 1.2 9.4 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 RUS81472.1 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RUS81472.1 - 0.034 14.7 0.1 1.2 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain SecA_PP_bind PF01043.20 RUS81472.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Dynamin_N PF00350.23 RUS81472.1 - 0.12 12.4 0.0 6.4 6.8 0.0 2.5 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 RUS81472.1 - 0.16 12.5 0.0 2.2 8.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter zf-CCHH PF10283.9 RUS81473.1 - 6.7e-11 42.0 7.9 1.1e-10 41.3 7.9 1.3 1 0 0 1 1 1 1 PBZ domain FHA PF00498.26 RUS81473.1 - 1.7e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 RUS81473.1 - 2e-05 24.7 0.0 4.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS81473.1 - 0.043 14.1 0.4 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 RUS81475.1 - 8.6e-05 22.3 10.0 0.00025 20.9 10.0 1.7 1 1 0 1 1 1 1 PHD-finger HalX PF08663.10 RUS81475.1 - 0.0051 17.1 3.3 0.0096 16.2 3.3 1.4 1 0 0 1 1 1 1 HalX domain C1_1 PF00130.22 RUS81475.1 - 0.012 15.4 8.3 0.039 13.8 3.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lectin_N PF03954.14 RUS81475.1 - 0.021 14.6 0.1 0.057 13.2 0.1 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ima1_N PF09779.9 RUS81475.1 - 0.73 10.7 7.0 0.23 12.3 3.3 2.0 2 1 0 2 2 2 0 Ima1 N-terminal domain C1_2 PF03107.16 RUS81475.1 - 2 8.8 6.4 1.2 9.6 2.3 2.2 2 0 0 2 2 2 0 C1 domain zf-C3HC4_3 PF13920.6 RUS81477.1 - 1.2e-12 47.5 16.0 2.1e-12 46.7 16.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS81477.1 - 4.7e-05 23.2 13.3 9.5e-05 22.2 13.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Hid1 PF12722.7 RUS81477.1 - 0.015 13.5 0.0 0.019 13.1 0.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 RUS81477.1 - 0.048 11.9 17.4 0.06 11.6 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_14 PF17978.1 RUS81477.1 - 0.69 10.4 8.0 1.5 9.3 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2457 PF10446.9 RUS81477.1 - 1.3 8.1 20.1 2.1 7.4 20.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 RUS81477.1 - 1.5 8.2 17.7 1.8 7.9 17.7 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_S64 PF08192.11 RUS81477.1 - 7.8 4.9 6.6 11 4.4 6.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 OGG_N PF07934.12 RUS81478.1 - 5.2e-36 123.4 4.7 1.8e-34 118.4 4.7 2.4 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 RUS81478.1 - 7.2e-14 52.2 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3848 PF12959.7 RUS81478.1 - 0.032 14.3 1.0 0.13 12.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) HHH PF00633.23 RUS81478.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif EF-hand_2 PF09068.11 RUS81478.1 - 0.25 11.5 1.6 14 5.9 1.8 2.3 1 1 0 1 1 1 0 EF hand LRR_4 PF12799.7 RUS81479.1 - 3.3e-10 40.1 13.7 2.9e-07 30.7 0.7 3.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS81479.1 - 3.5e-10 39.6 0.1 7.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS81479.1 - 3.6e-05 23.4 4.1 5.4e-05 22.9 2.5 2.2 2 0 0 2 2 2 1 Leucine rich repeat YfdX PF10938.8 RUS81479.1 - 0.062 13.2 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 YfdX protein IQ PF00612.27 RUS81479.1 - 0.3 11.0 3.6 0.12 12.2 0.5 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif LRR_1 PF00560.33 RUS81479.1 - 0.51 11.1 3.1 66 4.7 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat ParBc PF02195.18 RUS81480.1 - 1.4e-07 31.7 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain DUF4640 PF15480.6 RUS81480.1 - 0.0019 18.0 0.2 1.7 8.3 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4640) Sulfotransfer_2 PF03567.14 RUS81481.1 - 1.2e-29 104.0 5.7 1.1e-27 97.6 2.9 2.9 1 1 1 2 2 2 1 Sulfotransferase family DNA_pol_phi PF04931.13 RUS81482.1 - 0.00068 17.9 33.5 0.001 17.3 33.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi Roughex PF06020.11 RUS81482.1 - 0.002 17.3 4.6 0.0028 16.8 4.6 1.1 1 0 0 1 1 1 1 Drosophila roughex protein DUF4637 PF15470.6 RUS81482.1 - 0.0021 17.8 1.4 0.0037 17.0 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4637) eIF-3c_N PF05470.12 RUS81482.1 - 0.1 10.9 2.2 0.12 10.7 2.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RUS81482.1 - 0.14 10.4 22.3 0.17 10.1 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS81482.1 - 0.14 11.5 20.2 0.17 11.3 20.2 1.1 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 RUS81482.1 - 0.59 9.9 11.7 1.1 9.0 11.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BUD22 PF09073.10 RUS81482.1 - 0.71 9.2 15.8 0.89 8.8 15.8 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 RUS81482.1 - 0.85 8.0 16.2 1.1 7.6 16.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF2457 PF10446.9 RUS81482.1 - 2.4 7.2 42.7 4.1 6.4 42.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RUS81482.1 - 3.2 5.9 20.8 4.4 5.5 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 RUS81482.1 - 5.8 6.2 18.0 8.2 5.7 18.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rtf2 PF04641.12 RUS81483.1 - 0.0025 17.2 19.2 0.0025 17.2 19.2 2.4 3 0 0 3 3 3 1 Rtf2 RING-finger Coilin_N PF15862.5 RUS81483.1 - 0.0036 17.1 23.2 0.0036 17.1 23.2 2.4 3 0 0 3 3 3 1 Coilin N-terminus YL1 PF05764.13 RUS81483.1 - 0.0072 16.5 22.8 0.0072 16.5 22.8 2.9 3 0 0 3 3 3 1 YL1 nuclear protein EOS1 PF12326.8 RUS81483.1 - 0.061 13.2 13.8 0.1 12.5 5.4 2.2 2 0 0 2 2 2 0 N-glycosylation protein SpoIIP PF07454.11 RUS81483.1 - 0.44 10.0 26.7 0.02 14.4 11.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 RUS81483.1 - 3.7 7.2 33.1 0.45 10.2 17.1 2.3 2 0 0 2 2 2 0 Connexin DUF4228 PF14009.6 RUS81483.1 - 4.5 7.6 17.7 0.36 11.2 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) RPOL_N PF14700.6 RUS81483.1 - 5.7 6.2 31.2 0.031 13.7 12.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF5565 PF17720.1 RUS81486.1 - 0.039 12.8 0.0 0.074 11.9 0.0 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5565) Neuregulin PF02158.15 RUS81487.1 - 0.011 15.1 13.0 0.018 14.5 13.0 1.3 1 0 0 1 1 1 0 Neuregulin intracellular region SH3_1 PF00018.28 RUS81489.1 - 6.7e-25 86.4 1.6 1.2e-11 44.0 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 RUS81489.1 - 1.5e-21 75.9 2.0 4.7e-12 45.6 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 RUS81489.1 - 5.4e-20 71.5 2.6 7.9e-20 70.9 0.6 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 RUS81489.1 - 3.9e-17 61.7 0.1 3.6e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain HUN PF08729.10 RUS81489.1 - 0.0064 16.5 4.7 0.016 15.2 4.7 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SH3_3 PF08239.11 RUS81489.1 - 0.055 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RNA_pol_Rpc4 PF05132.14 RUS81490.1 - 4.9e-05 23.8 13.4 6.5e-05 23.4 13.4 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 DDHD PF02862.17 RUS81490.1 - 0.00056 20.1 6.9 0.00068 19.9 6.9 1.2 1 0 0 1 1 1 1 DDHD domain Vfa1 PF08432.10 RUS81490.1 - 0.0017 18.7 36.4 0.0027 18.1 36.4 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CCSAP PF15748.5 RUS81490.1 - 0.013 15.7 27.8 0.016 15.4 27.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 RUS81490.1 - 0.021 14.7 28.2 0.025 14.4 28.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 RUS81490.1 - 0.034 13.0 21.8 0.053 12.3 21.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 RUS81490.1 - 0.039 13.0 21.6 0.048 12.7 21.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 RUS81490.1 - 0.049 13.4 20.7 0.061 13.1 20.7 1.1 1 0 0 1 1 1 0 AAA domain SRP-alpha_N PF04086.13 RUS81490.1 - 0.078 12.9 33.3 0.13 12.2 33.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DAG_kinase_N PF14513.6 RUS81490.1 - 0.081 13.1 17.2 0.11 12.7 17.2 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CDC45 PF02724.14 RUS81490.1 - 0.09 11.1 24.1 0.11 10.8 24.1 1.0 1 0 0 1 1 1 0 CDC45-like protein FGF-BP1 PF06473.12 RUS81490.1 - 0.092 12.6 28.5 0.13 12.1 28.5 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PPL5 PF18168.1 RUS81490.1 - 0.12 11.7 18.4 0.18 11.1 18.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Paramyxo_ncap PF00973.19 RUS81490.1 - 0.14 11.1 12.3 0.17 10.8 12.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Serinc PF03348.15 RUS81490.1 - 0.2 10.5 7.3 0.25 10.2 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.8 RUS81490.1 - 0.28 10.7 19.0 0.47 10.0 19.0 1.4 1 0 0 1 1 1 0 Spt20 family RPOL_N PF14700.6 RUS81490.1 - 0.42 10.0 24.8 0.54 9.6 24.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Connexin PF00029.19 RUS81490.1 - 0.43 10.3 24.1 0.8 9.4 24.1 1.5 1 0 0 1 1 1 0 Connexin DUF262 PF03235.14 RUS81490.1 - 0.48 10.5 12.1 0.58 10.3 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 MMM1 PF10296.9 RUS81490.1 - 0.55 9.2 16.9 0.87 8.6 16.9 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF913 PF06025.12 RUS81490.1 - 0.59 9.1 12.8 0.72 8.8 12.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5308 PF17233.2 RUS81490.1 - 0.63 10.2 6.9 1.8 8.8 6.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5308) LMBR1 PF04791.16 RUS81490.1 - 0.63 8.9 7.2 0.65 8.8 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MCM_bind PF09739.9 RUS81490.1 - 0.96 7.8 21.2 1.1 7.6 21.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SID-1_RNA_chan PF13965.6 RUS81490.1 - 1.2 7.5 5.3 1.2 7.4 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Endostatin PF06482.11 RUS81490.1 - 1.2 8.5 12.1 1.5 8.2 12.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin LicD PF04991.13 RUS81490.1 - 1.2 9.2 27.9 1.6 8.8 27.9 1.2 1 0 0 1 1 1 0 LicD family Membralin PF09746.9 RUS81490.1 - 1.3 8.0 13.3 1.6 7.7 13.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Folliculin PF11704.8 RUS81490.1 - 1.6 8.6 14.7 2.5 8.0 14.7 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2052 PF09747.9 RUS81490.1 - 1.7 8.8 19.7 2.3 8.3 19.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 RUS81490.1 - 1.8 7.2 20.0 2.4 6.8 20.0 1.1 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 RUS81490.1 - 2 8.5 25.5 3 7.9 25.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CLN3 PF02487.17 RUS81490.1 - 2.3 7.2 13.4 2.9 6.9 13.4 1.1 1 0 0 1 1 1 0 CLN3 protein Hydin_ADK PF17213.3 RUS81490.1 - 2.3 8.4 11.5 3.6 7.8 11.5 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF4569 PF15133.6 RUS81490.1 - 2.5 7.7 18.7 3.4 7.3 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF2201_N PF13203.6 RUS81490.1 - 2.6 7.6 9.4 9.1 5.8 9.8 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Neur_chan_memb PF02932.16 RUS81490.1 - 2.6 8.1 14.0 3.2 7.7 14.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.8 RUS81490.1 - 2.8 6.7 39.6 3.9 6.3 39.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4228 PF14009.6 RUS81490.1 - 2.8 8.3 17.0 4.1 7.8 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AAA_23 PF13476.6 RUS81490.1 - 3.2 8.2 31.5 4.4 7.7 31.5 1.2 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 RUS81490.1 - 3.3 6.4 29.6 4.4 6.0 29.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 RUS81490.1 - 3.4 7.6 45.0 5 7.0 45.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PDCD2_C PF04194.13 RUS81490.1 - 3.7 7.6 16.4 5.8 7.0 16.4 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Peptidase_U57 PF05582.12 RUS81490.1 - 4.1 6.6 17.6 5.7 6.1 17.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF4614 PF15391.6 RUS81490.1 - 4.3 7.3 16.4 6.4 6.7 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF2370 PF10176.9 RUS81490.1 - 4.7 6.8 8.0 7.2 6.2 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ALMT PF11744.8 RUS81490.1 - 4.7 5.9 18.8 6.5 5.5 18.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter XRN_M PF17846.1 RUS81490.1 - 5.1 5.9 17.7 6.2 5.7 17.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RP-C_C PF11800.8 RUS81490.1 - 5.8 7.0 12.8 9.2 6.3 12.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2828 PF11443.8 RUS81490.1 - 5.9 4.8 30.7 7.3 4.5 30.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4551 PF15087.6 RUS81490.1 - 6.5 5.5 21.9 8.4 5.1 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rtf2 PF04641.12 RUS81490.1 - 9.8 5.4 42.8 14 4.9 42.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SOCS_box PF07525.16 RUS81491.1 - 2.5e-06 27.7 0.9 7.1e-06 26.3 0.9 1.8 1 0 0 1 1 1 1 SOCS box Ank_4 PF13637.6 RUS81491.1 - 4.4e-06 27.1 1.8 0.028 15.0 0.1 4.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS81491.1 - 1.9e-05 25.1 0.0 0.024 15.2 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS81491.1 - 0.037 14.4 0.1 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 RUS81492.1 - 2.6e-08 33.9 0.0 0.0063 16.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RUS81492.1 - 1.3e-07 31.8 0.0 6.1e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS81492.1 - 2.4e-07 31.2 0.0 0.014 15.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81492.1 - 7.9e-07 28.9 0.0 0.063 13.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RUS81492.1 - 1.2e-06 29.0 0.0 4.9e-06 27.0 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) CD225 PF04505.12 RUS81492.1 - 0.14 12.3 0.1 0.67 10.1 0.1 2.1 1 1 0 1 1 1 0 Interferon-induced transmembrane protein DUF3149 PF11346.8 RUS81493.1 - 1.4e-10 40.6 0.5 5.7 6.7 0.0 7.5 4 2 4 8 8 8 6 Protein of unknown function (DUF3149) DUF2417 PF10329.9 RUS81493.1 - 0.74 9.2 5.2 2 7.8 1.8 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) tRNA-synt_1d PF00750.19 RUS81499.1 - 3.1e-100 335.5 0.1 4.2e-100 335.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 RUS81499.1 - 6.9e-22 77.8 0.1 2.3e-21 76.2 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 RUS81499.1 - 0.0011 17.8 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RUS81499.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF4763 PF15960.5 RUS81499.1 - 0.059 12.7 1.6 0.12 11.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) tRNA-synt_1 PF00133.22 RUS81499.1 - 0.092 11.0 0.0 0.28 9.4 0.0 1.7 2 1 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) DivIC PF04977.15 RUS81499.1 - 0.17 11.7 7.3 1.1 9.1 1.5 2.9 2 0 0 2 2 2 0 Septum formation initiator KLRAQ PF10205.9 RUS81499.1 - 0.24 11.7 3.4 1.3 9.3 0.4 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein HALZ PF02183.18 RUS81499.1 - 0.74 10.1 6.8 1.4 9.2 1.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper 7tm_1 PF00001.21 RUS81500.1 - 5.7e-19 68.5 18.4 7.3e-18 64.8 18.4 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4477 PF14780.6 RUS81501.1 - 0.023 14.3 2.7 0.11 12.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) TBCC PF07986.12 RUS81501.1 - 0.13 12.0 7.1 4.8 6.9 0.9 3.2 2 2 0 2 2 2 0 Tubulin binding cofactor C PPP4R2 PF09184.11 RUS81501.1 - 0.46 10.0 5.1 5.9 6.4 0.6 2.8 2 2 0 2 2 2 0 PPP4R2 zf_CCCH_5 PF18384.1 RUS81501.1 - 2.6 8.2 7.6 37 4.5 1.3 4.3 3 2 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) Laminin_G_3 PF13385.6 RUS81502.1 - 3.2e-10 40.3 1.8 9.9e-10 38.8 1.8 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FAM163 PF15069.6 RUS81502.1 - 0.0089 16.5 0.3 0.021 15.3 0.3 1.6 1 0 0 1 1 1 1 FAM163 family EGF_2 PF07974.13 RUS81502.1 - 0.15 12.5 34.6 0.023 15.0 7.5 4.4 4 0 0 4 4 4 0 EGF-like domain GRP PF07172.11 RUS81503.1 - 0.00045 20.9 3.9 0.00045 20.9 3.9 2.1 2 0 0 2 2 2 1 Glycine rich protein family U79_P34 PF03064.16 RUS81503.1 - 0.35 10.2 7.6 0.49 9.7 7.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ARD PF03079.14 RUS81503.1 - 0.49 10.6 8.2 0.78 9.9 8.2 1.2 1 0 0 1 1 1 0 ARD/ARD' family Presenilin PF01080.17 RUS81503.1 - 3.6 6.2 5.0 6.9 5.3 4.6 1.6 2 0 0 2 2 2 0 Presenilin Med15 PF09606.10 RUS81503.1 - 5.9 5.4 23.7 7.5 5.1 23.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDRGK PF09756.9 RUS81503.1 - 7.8 6.0 20.1 12 5.4 20.1 1.2 1 0 0 1 1 1 0 DDRGK domain Galactosyl_T PF01762.21 RUS81504.1 - 3.2e-32 111.9 0.2 4.9e-32 111.3 0.2 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS81504.1 - 0.00054 19.5 0.2 0.00074 19.0 0.2 1.2 1 0 0 1 1 1 1 Fringe-like Synaptobrevin PF00957.21 RUS81505.1 - 1.7e-33 114.3 4.3 2.2e-33 113.9 4.3 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF4337 PF14235.6 RUS81505.1 - 0.0096 16.0 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) MCU PF04678.13 RUS81505.1 - 0.024 14.7 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4736 PF15883.5 RUS81505.1 - 2.1 8.0 5.1 4.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) IgGFc_binding PF17517.2 RUS81506.1 - 4.5e-13 49.1 2.2 5.6e-13 48.8 2.2 1.2 1 0 0 1 1 1 1 IgGFc binding protein DUF5639 PF18690.1 RUS81507.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5639) Peptidase_C39_2 PF13529.6 RUS81508.1 - 0.04 14.5 1.8 11 6.6 0.1 3.3 2 1 1 3 3 3 0 Peptidase_C39 like family HLH PF00010.26 RUS81509.1 - 3.9e-15 55.5 5.7 6.2e-15 54.9 5.7 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS81509.1 - 4.9e-12 45.8 0.1 1.4e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Hairy Orange Nucleoporin_FG PF13634.6 RUS81510.1 - 0.001 19.9 38.3 0.001 19.9 38.3 14.1 1 1 10 12 12 12 5 Nucleoporin FG repeat region Ocnus PF05005.15 RUS81510.1 - 0.079 13.1 2.1 6 7.1 0.1 2.8 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) DUF4611 PF15387.6 RUS81510.1 - 2 8.7 4.7 5.1 7.4 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Glyco_hydro_79n PF03662.14 RUS81511.1 - 1.4e-14 53.8 0.0 8.9e-14 51.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain AP3D1 PF06375.11 RUS81512.1 - 4.5e-15 56.2 18.1 4.5e-15 56.2 18.1 3.6 2 1 0 3 3 3 2 AP-3 complex subunit delta-1 AP4E_app_platf PF14807.6 RUS81512.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Alpha_adaptinC2 PF02883.20 RUS81512.1 - 0.068 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain NST1 PF13945.6 RUS81512.1 - 2.6 8.1 41.2 0.65 10.1 5.8 3.3 3 0 0 3 3 3 0 Salt tolerance down-regulator FlaE PF07559.14 RUS81513.1 - 0.021 15.4 0.0 0.029 14.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar basal body protein FlaE HMG_box PF00505.19 RUS81514.1 - 8.4e-17 61.4 0.6 2.2e-16 60.0 0.6 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS81514.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 2.4 2 0 0 2 2 2 1 HMG-box domain End_tail_spike PF12219.8 RUS81514.1 - 0.057 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase Suf PF05843.14 RUS81514.1 - 0.06 13.3 9.2 0.1 12.6 9.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 RUS81514.1 - 4.6 7.2 7.8 8.5 6.4 7.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 RUS81515.1 - 0.0065 15.9 16.5 0.0065 15.9 16.5 3.1 3 0 0 3 3 3 1 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 RUS81515.1 - 0.036 13.9 32.3 1 9.2 1.7 3.1 3 0 0 3 3 3 0 SpoIIIAH-like protein Afi1 PF07792.12 RUS81515.1 - 0.039 14.4 47.9 0.4 11.2 14.4 3.5 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 RUS81515.1 - 0.076 11.1 130.2 0.099 10.7 40.8 3.0 3 0 0 3 3 3 0 DNA polymerase phi CDC45 PF02724.14 RUS81515.1 - 0.23 9.7 83.4 0.017 13.4 15.9 3.0 3 0 0 3 3 3 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 RUS81515.1 - 1.3 9.5 32.3 1.4 9.4 14.8 3.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 CLN3 PF02487.17 RUS81515.1 - 1.5 7.8 8.8 9.7 5.1 10.1 1.6 2 0 0 2 2 2 0 CLN3 protein Neur_chan_memb PF02932.16 RUS81515.1 - 3.3 7.7 5.3 5 7.1 5.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 RUS81515.1 - 7.8 6.2 20.9 20 4.8 17.3 2.5 3 0 0 3 3 3 0 Connexin PA26 PF04636.13 RUS81515.1 - 8.1 5.2 9.9 12 4.6 9.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ank_2 PF12796.7 RUS81516.1 - 4.5e-23 81.6 3.2 6.2e-08 33.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS81516.1 - 9e-19 67.6 5.6 1.9e-10 41.0 0.1 4.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS81516.1 - 1.3e-17 63.4 4.4 6.6e-06 26.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS81516.1 - 2.9e-17 62.5 4.3 1.2e-08 35.1 0.1 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81516.1 - 8.6e-16 56.5 5.3 1.5e-05 25.0 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat KN_motif PF12075.8 RUS81516.1 - 6.1e-11 41.9 0.1 1.7e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 KN motif Pkinase PF00069.25 RUS81518.1 - 1.2e-42 146.1 0.0 1.7e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81518.1 - 1.6e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS81518.1 - 2.2e-07 30.0 0.0 4.5e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS81518.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS81518.1 - 0.0043 17.0 0.0 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS81518.1 - 0.022 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS81518.1 - 0.033 13.1 0.4 0.072 12.0 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain AAA PF00004.29 RUS81519.1 - 8.3e-47 158.9 0.0 1.3e-40 138.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 RUS81519.1 - 3.6e-19 68.6 0.1 1.2e-18 66.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 RUS81519.1 - 6.5e-10 38.7 0.1 2.8e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 RUS81519.1 - 6.9e-05 23.3 0.0 0.0003 21.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 RUS81519.1 - 8.9e-05 22.7 0.0 0.00053 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RUS81519.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 RUS81519.1 - 0.0069 16.7 0.1 0.12 12.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RUS81519.1 - 0.011 16.3 0.5 0.061 13.9 0.0 2.7 2 0 0 2 2 1 0 AAA domain DUF498 PF04430.14 RUS81519.1 - 0.012 15.7 0.0 2.2 8.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) AAA_5 PF07728.14 RUS81519.1 - 0.016 15.2 0.0 0.094 12.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS81519.1 - 0.031 14.0 0.0 0.095 12.4 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RUS81519.1 - 0.066 13.6 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 RUS81519.1 - 0.096 12.1 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LPP PF04728.13 RUS81521.1 - 0.0097 16.3 2.0 0.0097 16.3 2.0 4.1 3 2 0 3 3 3 1 Lipoprotein leucine-zipper KxDL PF10241.9 RUS81521.1 - 0.018 15.3 3.2 0.018 15.3 3.2 4.2 1 1 4 5 5 5 0 Uncharacterized conserved protein FAM184 PF15665.5 RUS81521.1 - 0.27 11.0 53.3 3.8 7.2 20.8 2.9 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B SMN PF06003.12 RUS81521.1 - 1 8.6 5.3 0.84 8.8 3.8 1.5 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Rx_N PF18052.1 RUS81521.1 - 1.8 8.9 25.5 0.051 13.8 1.3 3.8 2 1 2 4 4 4 0 Rx N-terminal domain CALCOCO1 PF07888.11 RUS81521.1 - 2.7 6.8 51.4 5.5 5.7 51.0 1.7 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4250 PF14056.6 RUS81521.1 - 4.9 7.2 10.3 2.2 8.3 1.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) WXG100 PF06013.12 RUS81521.1 - 5.3 7.3 23.2 22 5.4 2.8 3.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 RUS81521.1 - 8 7.0 12.7 1.4 9.5 0.4 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 RUS81521.1 - 9.5 6.2 9.6 29 4.6 0.3 2.9 1 1 1 2 2 2 0 Apolipoprotein O FAM184 PF15665.5 RUS81522.1 - 4.9e-47 160.4 31.8 4.9e-47 160.4 31.8 5.6 1 1 3 4 4 4 1 Family with sequence similarity 184, A and B DUF1640 PF07798.11 RUS81522.1 - 0.00016 21.7 4.7 0.00016 21.7 4.7 7.1 1 1 6 7 7 7 2 Protein of unknown function (DUF1640) Filament PF00038.21 RUS81522.1 - 0.0004 20.1 42.4 0.0004 20.1 42.4 4.9 1 1 4 5 5 5 4 Intermediate filament protein Fez1 PF06818.15 RUS81522.1 - 0.0028 18.1 23.1 0.0028 18.1 23.1 6.6 1 1 6 7 7 7 2 Fez1 HMMR_N PF15905.5 RUS81522.1 - 0.0031 17.0 28.4 0.0031 17.0 28.4 6.1 1 1 5 6 6 6 2 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 RUS81522.1 - 0.0034 17.4 2.3 0.0034 17.4 2.3 12.2 6 4 5 12 12 12 2 TolA binding protein trimerisation DUF4407 PF14362.6 RUS81522.1 - 0.0075 15.7 16.9 0.0075 15.7 16.9 6.1 1 1 3 5 5 5 3 Domain of unknown function (DUF4407) GD_N PF16030.5 RUS81522.1 - 0.55 10.6 3.8 0.98 9.7 1.1 2.9 2 1 0 2 2 2 0 Serine protease gd N-terminus YvrJ PF12841.7 RUS81522.1 - 4.1 7.0 9.4 29 4.3 0.1 4.6 4 0 0 4 4 4 0 YvrJ protein family 7tm_1 PF00001.21 RUS81523.1 - 1.2e-11 44.4 15.9 1.7e-11 44.0 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS81523.1 - 4.8e-11 42.5 25.2 1.3e-08 34.6 14.2 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw HemY_N PF07219.13 RUS81523.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.9 2 1 2 4 4 4 0 HemY protein N-terminus TAS2R PF05296.13 RUS81523.1 - 0.4 9.7 19.5 0.011 14.8 12.0 2.1 2 1 0 2 2 2 0 Taste receptor protein (TAS2R) Pkinase_Tyr PF07714.17 RUS81524.1 - 1.1e-39 136.3 0.0 2.1e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS81524.1 - 1.3e-28 100.1 1.1 2.6e-28 99.1 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain RIH_assoc PF08454.11 RUS81524.1 - 0.29 11.0 4.2 1.7 8.5 0.4 2.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated Pkinase_Tyr PF07714.17 RUS81525.1 - 4.8e-10 39.2 0.1 7.1e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS81525.1 - 5.4e-05 22.7 1.4 8.3e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Roughex PF06020.11 RUS81525.1 - 1 8.4 6.1 1.9 7.5 6.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Cnd2 PF05786.14 RUS81525.1 - 1.3 7.6 6.7 2 7.0 6.7 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 eIF3_subunit PF08597.10 RUS81525.1 - 1.7 8.5 10.9 0.27 11.1 7.3 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 RUS81525.1 - 5.5 5.2 7.7 7.7 4.7 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_23 PF13489.6 RUS81526.1 - 3.6e-17 62.7 0.0 7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS81526.1 - 7.1e-17 62.0 0.0 1.8e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS81526.1 - 2e-15 57.2 0.0 5.3e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS81526.1 - 7.5e-12 45.7 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS81526.1 - 8.9e-11 41.8 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS81526.1 - 5.1e-08 32.5 0.0 1.2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 RUS81526.1 - 0.00026 20.6 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 RUS81526.1 - 0.0021 17.3 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family TehB PF03848.14 RUS81526.1 - 0.0024 17.3 0.1 0.0058 16.1 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB DUF4159 PF13709.6 RUS81526.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) CheR PF01739.18 RUS81526.1 - 0.043 13.3 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain VWA_3 PF13768.6 RUS81526.1 - 0.13 12.2 0.2 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Methyltransf_16 PF10294.9 RUS81526.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MADF_DNA_bdg PF10545.9 RUS81527.1 - 7.9e-15 54.9 0.0 9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 RUS81527.1 - 0.006 16.6 0.1 0.0079 16.3 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 RUS81527.1 - 0.014 15.5 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Neur_chan_memb PF02932.16 RUS81528.1 - 3.2e-08 33.9 1.6 3.2e-08 33.9 1.6 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Ninjurin PF04923.12 RUS81528.1 - 0.03 14.2 0.3 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 Ninjurin DUF4834 PF16118.5 RUS81528.1 - 0.5 11.4 0.1 0.5 11.4 0.1 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Ion_trans PF00520.31 RUS81528.1 - 0.7 9.1 10.6 2.9 7.1 10.4 1.9 1 1 0 1 1 1 0 Ion transport protein DUF3278 PF11683.8 RUS81528.1 - 6.7 6.8 8.6 11 6.1 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) zf-ANAPC11 PF12861.7 RUS81529.1 - 1.7e-38 130.6 15.2 2.4e-38 130.1 15.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RUS81529.1 - 1.1e-22 80.1 15.5 1.1e-22 80.1 15.5 1.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RUS81529.1 - 3.6e-07 30.4 22.4 4.3e-06 27.0 19.8 3.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS81529.1 - 0.00072 19.5 12.2 0.01 15.8 11.5 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS81529.1 - 0.008 16.3 2.4 0.008 16.3 2.4 2.5 3 1 0 2 2 2 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 RUS81529.1 - 0.018 15.2 5.1 0.018 15.2 5.1 2.3 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_3 PF13920.6 RUS81529.1 - 0.025 14.4 14.6 0.084 12.7 10.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS81529.1 - 0.032 14.1 14.3 0.032 14.1 14.3 2.9 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS81529.1 - 0.062 13.2 21.3 0.33 10.9 19.9 2.9 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RUS81529.1 - 0.072 12.9 6.8 0.12 12.2 6.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 RUS81529.1 - 1.1 9.3 19.0 22 5.1 18.8 2.9 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 RUS81529.1 - 2.2 8.0 19.9 1.5 8.5 15.5 2.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 RUS81529.1 - 2.5 7.9 17.6 27 4.6 17.6 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 RUS81529.1 - 3.1 8.1 17.7 23 5.2 17.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 RUS81529.1 - 3.4 7.5 16.6 0.17 11.7 2.4 2.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ank_4 PF13637.6 RUS81530.1 - 2.2e-25 88.7 0.0 1.5e-08 35.0 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS81530.1 - 5.2e-24 84.0 0.0 1.7e-06 28.2 0.0 4.4 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS81530.1 - 1.3e-23 83.4 0.2 1.8e-08 34.9 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS81530.1 - 9.7e-18 62.4 0.2 0.02 15.4 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 RUS81530.1 - 1.9e-12 47.0 0.4 0.17 12.4 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat NHL PF01436.21 RUS81531.1 - 2.1e-23 81.1 8.2 1.8e-07 30.8 1.4 5.4 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 RUS81531.1 - 0.00018 21.1 0.1 0.23 11.0 0.0 3.0 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 RUS81531.1 - 0.12 12.3 0.3 2.8 7.8 0.0 2.7 2 1 1 3 3 3 0 Esterase-like activity of phytase DUF2946 PF11162.8 RUS81532.1 - 0.022 15.4 0.4 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Tubulin PF00091.25 RUS81533.1 - 8.3e-68 228.5 0.0 1.1e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS81533.1 - 4.2e-50 169.1 0.0 7.2e-50 168.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS81533.1 - 0.00088 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF3408 PF11888.8 RUS81534.1 - 0.29 11.3 1.6 0.63 10.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) zf-C2H2_4 PF13894.6 RUS81536.1 - 5.8e-07 29.8 31.8 0.001 19.7 0.1 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS81536.1 - 6.4e-07 29.5 13.3 0.00068 20.0 0.1 4.7 4 1 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS81536.1 - 0.00033 20.9 15.4 0.25 11.7 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS81536.1 - 0.015 15.3 0.1 0.015 15.3 0.1 4.3 5 0 0 5 5 4 0 C2H2-type zinc finger zf-CCHC_2 PF13696.6 RUS81536.1 - 0.017 14.9 5.8 0.68 9.8 0.3 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-met PF12874.7 RUS81536.1 - 0.021 15.2 0.2 0.021 15.2 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RUS81536.1 - 0.033 14.6 1.5 0.033 14.6 1.5 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 RUS81536.1 - 0.077 13.1 0.4 0.077 13.1 0.4 3.2 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 RUS81536.1 - 0.26 11.6 22.4 1 9.7 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-UDP PF14569.6 RUS81536.1 - 0.57 10.3 7.5 0.12 12.5 1.1 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger C1_2 PF03107.16 RUS81536.1 - 0.7 10.3 21.3 1.1 9.6 5.4 4.0 2 1 1 3 3 3 0 C1 domain Elf1 PF05129.13 RUS81536.1 - 0.85 9.7 10.9 1.9 8.6 1.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 RUS81536.1 - 1.5 8.8 9.3 0.2 11.6 0.3 3.0 1 1 2 3 3 3 0 Putative transposase DNA-binding domain DpnI PF06044.12 RUS81536.1 - 2.4 7.7 6.2 1.2 8.8 0.9 2.1 1 1 1 2 2 2 0 Dam-replacing family CpXC PF14353.6 RUS81536.1 - 3 7.9 10.1 21 5.2 0.5 3.0 1 1 2 3 3 3 0 CpXC protein zf-MYST PF17772.1 RUS81536.1 - 4.7 6.9 0.0 4.7 6.9 0.0 3.1 1 1 2 3 3 3 0 MYST family zinc finger domain zf-C2H2_9 PF16293.5 RUS81536.1 - 6 6.8 12.6 7.6 6.5 0.6 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 RUS81537.1 - 4.2e-14 52.0 48.4 0.00098 19.8 0.4 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS81537.1 - 4.3e-08 33.2 46.9 0.0043 17.4 1.9 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81537.1 - 7e-05 23.1 43.0 0.047 14.2 0.8 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-met PF12874.7 RUS81537.1 - 0.00014 22.1 10.0 0.0031 17.8 2.0 5.9 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS81537.1 - 0.0018 18.6 30.8 0.021 15.1 10.4 4.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RUS81537.1 - 0.0061 16.5 0.6 0.0061 16.5 0.6 7.0 7 2 0 7 7 7 1 C2H2-type zinc finger WAC_Acf1_DNA_bd PF10537.9 RUS81537.1 - 0.032 14.7 2.7 0.12 12.9 0.2 2.9 2 2 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-Sec23_Sec24 PF04810.15 RUS81537.1 - 0.18 11.9 0.1 0.18 11.9 0.1 5.4 5 1 0 5 5 5 0 Sec23/Sec24 zinc finger zinc_ribbon_9 PF14369.6 RUS81537.1 - 0.74 10.1 10.3 5.4 7.4 0.6 4.4 5 0 0 5 5 5 0 zinc-ribbon zf-C2H2_3rep PF18868.1 RUS81537.1 - 0.91 10.2 26.4 2.6 8.7 1.4 4.5 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 RUS81537.1 - 1.2 9.5 7.1 7.8 6.9 0.6 3.0 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.8 RUS81537.1 - 5.1 7.5 32.2 0.43 10.9 1.7 6.3 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RUS81538.1 - 2.5e-36 121.2 88.5 1.6e-05 25.3 1.7 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS81538.1 - 3.7e-30 102.7 92.9 3.8e-05 23.9 2.6 11.2 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81538.1 - 4.9e-22 77.3 83.7 0.00037 20.8 0.1 11.6 12 0 0 12 12 11 8 Zinc-finger double domain zf-Di19 PF05605.12 RUS81538.1 - 2.3e-13 50.2 57.2 0.0046 17.2 0.1 7.2 4 2 3 7 7 7 6 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS81538.1 - 2.2e-12 46.9 57.2 0.015 15.7 0.2 11.2 11 0 0 11 11 11 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS81538.1 - 4.2e-08 33.3 51.2 0.19 12.1 0.1 10.8 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS81538.1 - 1.2e-06 28.3 12.9 1.2e-05 25.2 3.0 12.3 13 2 0 13 13 12 6 C2H2-type zinc finger GAGA PF09237.11 RUS81538.1 - 0.00031 20.5 22.3 0.026 14.3 0.0 6.5 4 3 3 7 7 7 1 GAGA factor zf-C2H2_2 PF12756.7 RUS81538.1 - 0.0018 18.6 9.2 0.0018 18.6 9.2 7.6 1 1 5 6 6 6 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS81538.1 - 0.018 15.2 41.9 0.54 10.4 1.0 8.2 3 3 7 10 10 10 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 RUS81538.1 - 0.032 14.0 0.5 0.032 14.0 0.5 9.6 11 0 0 11 11 10 0 zinc-finger C2H2-type Guanylin PF02058.15 RUS81538.1 - 0.21 12.1 3.2 3.8 8.0 0.1 3.3 3 0 0 3 3 3 0 Guanylin precursor Rad50_zn_hook PF04423.14 RUS81538.1 - 0.26 11.2 13.0 9.4 6.2 0.0 5.6 5 0 0 5 5 5 0 Rad50 zinc hook motif DUF2225 PF09986.9 RUS81538.1 - 0.29 10.8 28.0 2.8 7.6 0.1 5.7 4 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_UBZ PF18439.1 RUS81538.1 - 0.76 9.4 44.0 2.3 7.9 0.3 10.6 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 RUS81538.1 - 0.81 10.0 37.6 5.5 7.3 0.4 9.1 10 0 0 10 10 10 0 zinc-ribbon zf-C2H2_9 PF16293.5 RUS81538.1 - 0.86 9.5 0.1 0.86 9.5 0.1 8.8 7 3 4 11 11 10 0 C2H2 type zinc-finger (1 copy) ARS2 PF04959.13 RUS81538.1 - 1.3 9.3 13.6 0.25 11.7 1.7 3.9 3 1 1 4 4 4 0 Arsenite-resistance protein 2 BIR PF00653.21 RUS81538.1 - 3.5 8.4 38.2 1.7 9.3 3.8 6.2 1 1 5 6 6 6 0 Inhibitor of Apoptosis domain DNA_ligase_ZBD PF03119.16 RUS81538.1 - 5.1 7.2 19.1 9.4 6.4 0.1 5.1 5 0 0 5 5 5 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 RUS81538.1 - 9.4 6.3 36.8 92 3.1 3.8 7.0 2 2 0 2 2 1 0 zinc-ribbons PRCC PF10253.9 RUS81539.1 - 1.8e-31 110.6 14.1 1.8e-31 110.6 14.1 3.5 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting PIG-S PF10510.9 RUS81540.1 - 7.7e-118 394.5 0.5 8.9e-118 394.3 0.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein PI3_PI4_kinase PF00454.27 RUS81541.1 - 3.3e-58 197.4 0.0 4.1e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 RUS81541.1 - 0.073 13.0 5.2 0.15 12.0 5.2 1.4 1 0 0 1 1 1 0 Janus-atracotoxin zf-U1 PF06220.12 RUS81542.1 - 1e-09 38.0 3.5 1e-09 38.0 3.5 2.0 2 0 0 2 2 2 1 U1 zinc finger zf-CCCH PF00642.24 RUS81542.1 - 1.3e-08 34.5 2.1 2.5e-08 33.6 2.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS81542.1 - 1.1e-06 28.5 3.7 2.1e-06 27.6 3.7 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 RUS81542.1 - 1.3e-06 28.1 2.6 2.2e-06 27.3 2.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RUS81542.1 - 0.0066 16.9 1.3 0.013 15.9 1.3 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-H2C2_2 PF13465.6 RUS81542.1 - 0.09 13.2 0.6 0.23 11.9 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger double domain Torus PF16131.5 RUS81542.1 - 0.099 13.3 0.6 0.099 13.3 0.6 1.9 1 1 1 2 2 2 0 Torus domain zf-C2H2 PF00096.26 RUS81542.1 - 0.1 13.1 1.1 0.36 11.4 1.1 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS81542.1 - 0.27 11.6 5.7 1.3 9.4 5.7 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RUS81542.1 - 0.38 11.7 0.2 0.38 11.7 0.2 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger Adaptin_binding PF10199.9 RUS81543.1 - 5.2e-20 72.3 0.1 1.2e-19 71.1 0.1 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 IQ PF00612.27 RUS81544.1 - 0.0027 17.4 0.7 0.0074 16.0 0.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif TBCC PF07986.12 RUS81545.1 - 0.00066 19.4 19.9 2.3 8.0 1.7 4.6 1 1 3 4 4 4 4 Tubulin binding cofactor C LicD PF04991.13 RUS81546.1 - 5.5e-16 59.4 0.3 2.5e-12 47.4 0.2 2.3 2 0 0 2 2 2 2 LicD family Glyco_hydro_20 PF00728.22 RUS81547.1 - 7.7e-07 28.8 0.0 3.2e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Arfaptin PF06456.13 RUS81548.1 - 4.7e-71 239.0 7.6 5.8e-71 238.7 7.6 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 RUS81548.1 - 0.017 14.8 9.7 0.022 14.5 8.0 1.8 1 1 1 2 2 2 0 BAR domain of APPL family GAS PF13851.6 RUS81548.1 - 0.29 10.5 7.1 0.13 11.6 1.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding zf-Tim10_DDP PF02953.15 RUS81549.1 - 4.1e-12 45.6 2.0 4.1e-12 45.6 2.0 2.0 3 0 0 3 3 3 1 Tim10/DDP family zinc finger F-actin_cap_A PF01267.17 RUS81549.1 - 0.004 16.6 0.6 0.0047 16.4 0.6 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF4805 PF16063.5 RUS81549.1 - 0.025 13.9 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) NDUF_C2 PF06374.11 RUS81550.1 - 3.5e-16 59.3 0.0 3.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) GDI PF00996.18 RUS81551.1 - 3.7e-12 45.5 0.0 5.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 RUS81551.1 - 0.059 13.6 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.18 RUS81552.1 - 4.7e-49 167.1 0.0 6.8e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Neur_chan_memb PF02932.16 RUS81553.1 - 1.1e-52 179.5 28.3 1.1e-24 87.8 7.6 3.1 3 0 0 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS81553.1 - 1.7e-29 102.9 0.3 2.5e-29 102.3 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF3240 PF11582.8 RUS81553.1 - 0.0033 17.5 0.0 5 7.3 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3240) MRG PF05712.13 RUS81554.1 - 2.7e-45 154.1 0.0 4.6e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 RUS81554.1 - 9.3e-05 22.2 0.6 0.0002 21.2 0.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Myosin_tail_1 PF01576.19 RUS81555.1 - 5.4e-82 276.2 148.9 7e-82 275.8 148.9 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 RUS81555.1 - 6e-08 32.6 132.8 0.031 13.9 45.1 8.8 1 1 4 5 5 5 3 Intermediate filament protein DUF1664 PF07889.12 RUS81555.1 - 2.4e-05 24.3 85.1 0.065 13.3 2.8 10.3 2 2 8 10 10 10 6 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS81555.1 - 0.00011 21.2 26.3 0.00011 21.2 26.3 7.3 2 1 5 7 7 7 5 Spc7 kinetochore protein KASH_CCD PF14662.6 RUS81555.1 - 0.00024 21.0 133.9 0.00046 20.1 16.7 7.8 1 1 6 7 7 7 4 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 RUS81555.1 - 0.00077 19.4 18.8 0.00077 19.4 18.8 6.7 2 2 5 7 7 7 1 Ezrin/radixin/moesin family Lebercilin PF15619.6 RUS81555.1 - 0.00088 19.0 32.4 0.00088 19.0 32.4 7.2 2 1 5 8 8 8 2 Ciliary protein causing Leber congenital amaurosis disease FAM184 PF15665.5 RUS81555.1 - 0.004 17.0 8.1 0.004 17.0 8.1 6.6 2 1 4 6 6 6 2 Family with sequence similarity 184, A and B HMMR_N PF15905.5 RUS81555.1 - 0.0063 16.0 16.8 0.0063 16.0 16.8 6.2 1 1 5 6 6 5 1 Hyaluronan mediated motility receptor N-terminal Tup_N PF08581.10 RUS81555.1 - 0.012 15.9 5.3 0.012 15.9 5.3 9.8 3 3 8 12 12 12 0 Tup N-terminal DUF4472 PF14739.6 RUS81555.1 - 0.017 15.9 8.0 0.017 15.9 8.0 10.2 1 1 9 11 11 10 0 Domain of unknown function (DUF4472) ATG16 PF08614.11 RUS81555.1 - 0.48 10.6 159.6 0.21 11.8 21.1 8.5 2 2 6 8 8 8 0 Autophagy protein 16 (ATG16) SHE3 PF17078.5 RUS81555.1 - 1.2 8.8 114.0 0.2 11.3 9.0 6.9 1 1 5 6 6 6 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 RUS81555.1 - 1.4 9.0 85.9 0.062 13.4 1.5 13.1 9 1 6 15 15 15 0 bZIP transcription factor HALZ PF02183.18 RUS81555.1 - 1.7 9.0 72.3 0.27 11.5 4.2 12.6 9 2 7 16 16 14 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 RUS81555.1 - 5.4 7.1 149.9 0.13 12.3 13.4 11.3 1 1 8 10 10 10 0 TPR/MLP1/MLP2-like protein LRR_6 PF13516.6 RUS81556.1 - 4.7e-26 88.6 17.6 0.007 16.3 0.0 10.2 10 0 0 10 10 10 7 Leucine Rich repeat EF-hand_7 PF13499.6 RUS81556.1 - 3e-06 27.6 0.1 3e-06 27.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair LRR_1 PF00560.33 RUS81556.1 - 7.9e-06 25.7 13.7 48 5.1 0.0 9.3 10 0 0 10 10 10 0 Leucine Rich Repeat EF-hand_1 PF00036.32 RUS81556.1 - 1.2e-05 24.4 7.9 0.0035 16.8 0.2 3.7 3 0 0 3 3 3 2 EF hand LRR_4 PF12799.7 RUS81556.1 - 4.8e-05 23.6 19.0 0.031 14.7 1.7 6.0 2 2 2 5 5 5 2 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 RUS81556.1 - 0.00013 21.6 1.0 0.012 15.5 0.1 3.6 3 1 1 4 4 3 2 EF-hand domain LRR_8 PF13855.6 RUS81556.1 - 0.00021 21.0 15.9 0.0031 17.2 1.2 5.9 3 2 2 5 5 5 1 Leucine rich repeat EF-hand_8 PF13833.6 RUS81556.1 - 0.00041 20.1 0.2 0.0018 18.1 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair GlutR_dimer PF00745.20 RUS81556.1 - 0.0011 19.4 3.9 0.084 13.3 2.8 3.2 3 0 0 3 3 3 1 Glutamyl-tRNAGlu reductase, dimerisation domain EF-hand_5 PF13202.6 RUS81556.1 - 0.037 13.5 0.2 0.037 13.5 0.2 3.5 3 0 0 3 3 3 0 EF hand DUF4604 PF15377.6 RUS81556.1 - 0.079 13.4 1.6 0.32 11.4 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) NTF2 PF02136.20 RUS81557.1 - 2e-24 86.4 0.0 2.3e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 RUS81557.1 - 3.1e-07 30.5 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Cas_Csx8 PF09657.10 RUS81557.1 - 0.03 13.3 0.6 0.053 12.5 0.1 1.5 2 0 0 2 2 2 0 CRISPR-associated protein Csx8 (Cas_Csx8) Nucleos_tra2_C PF07662.13 RUS81559.1 - 6.1e-57 192.8 4.6 6.1e-57 192.8 4.6 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS81559.1 - 1.2e-18 67.5 1.1 1.3e-17 64.2 0.2 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS81559.1 - 0.0097 16.2 6.7 0.0097 16.2 6.7 3.1 2 1 1 3 3 3 1 Nucleoside recognition Pkinase PF00069.25 RUS81560.1 - 2.3e-50 171.4 0.0 3.2e-31 108.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81560.1 - 1.3e-26 93.5 0.0 4.5e-13 49.1 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RUS81560.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 RUS81560.1 - 0.037 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Rtf2 PF04641.12 RUS81561.1 - 1.2e-05 24.9 10.0 1.6e-05 24.4 10.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger OATP PF03137.20 RUS81561.1 - 1.5e-05 23.6 3.7 2.1e-05 23.0 3.7 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 RUS81561.1 - 6.8e-05 22.7 6.3 9e-05 22.3 6.3 1.2 1 0 0 1 1 1 1 Connexin DAG_kinase_N PF14513.6 RUS81561.1 - 0.00097 19.4 2.3 0.0012 19.0 2.3 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus CPSF100_C PF13299.6 RUS81561.1 - 0.0011 19.2 2.9 0.0014 18.9 2.9 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Orthoreo_P10 PF07204.11 RUS81561.1 - 0.0019 18.1 9.1 0.35 10.9 0.4 4.2 1 1 3 4 4 4 1 Orthoreovirus membrane fusion protein p10 DUF5308 PF17233.2 RUS81561.1 - 0.0023 18.2 1.5 0.0043 17.3 1.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Zip PF02535.22 RUS81561.1 - 0.0027 17.0 1.2 0.0034 16.7 1.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter V_ATPase_I PF01496.19 RUS81561.1 - 0.0047 14.9 6.9 0.0058 14.6 6.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DDHD PF02862.17 RUS81561.1 - 0.0049 17.1 0.4 0.0055 16.9 0.4 1.1 1 0 0 1 1 1 1 DDHD domain EOS1 PF12326.8 RUS81561.1 - 0.006 16.5 0.9 0.0078 16.2 0.9 1.2 1 0 0 1 1 1 1 N-glycosylation protein Presenilin PF01080.17 RUS81561.1 - 0.0085 14.9 1.4 0.011 14.6 1.4 1.2 1 0 0 1 1 1 1 Presenilin CLN3 PF02487.17 RUS81561.1 - 0.011 14.8 1.3 0.014 14.5 1.3 1.2 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 RUS81561.1 - 0.012 16.2 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Eapp_C PF10238.9 RUS81561.1 - 0.013 15.5 11.6 0.021 14.9 11.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein SID-1_RNA_chan PF13965.6 RUS81561.1 - 0.016 13.6 0.2 0.021 13.3 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sm_multidrug_ex PF06695.11 RUS81561.1 - 0.017 15.8 1.0 0.033 14.8 1.0 1.5 1 0 0 1 1 1 0 Putative small multi-drug export protein FAM176 PF14851.6 RUS81561.1 - 0.018 14.7 1.2 0.025 14.2 1.2 1.2 1 0 0 1 1 1 0 FAM176 family TagA PF12561.8 RUS81561.1 - 0.021 15.2 0.0 0.031 14.7 0.0 1.4 1 1 0 1 1 1 0 ToxR activated gene A lipoprotein domain AAA_11 PF13086.6 RUS81561.1 - 0.035 13.9 6.8 0.045 13.5 6.8 1.1 1 0 0 1 1 1 0 AAA domain Tim54 PF11711.8 RUS81561.1 - 0.037 12.8 11.8 0.048 12.4 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rxt3 PF08642.10 RUS81561.1 - 0.051 14.4 3.7 0.059 14.2 2.2 1.9 2 0 0 2 2 1 0 Histone deacetylation protein Rxt3 MDM31_MDM32 PF08118.11 RUS81561.1 - 0.051 12.2 4.9 0.063 11.9 4.9 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4770 PF15994.5 RUS81561.1 - 0.059 13.6 13.8 0.076 13.2 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FHIPEP PF00771.20 RUS81561.1 - 0.075 11.5 0.8 0.09 11.2 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family Vfa1 PF08432.10 RUS81561.1 - 0.083 13.2 25.7 0.12 12.7 25.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 K_trans PF02705.16 RUS81561.1 - 0.092 11.2 2.4 0.12 10.9 2.4 1.1 1 0 0 1 1 1 0 K+ potassium transporter Agouti PF05039.12 RUS81561.1 - 0.093 13.5 6.7 0.18 12.5 6.7 1.5 1 0 0 1 1 1 0 Agouti protein RP-C_C PF11800.8 RUS81561.1 - 0.1 12.7 3.8 0.15 12.1 3.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RPN2_C PF18004.1 RUS81561.1 - 0.12 12.3 25.6 0.16 11.9 25.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 RUS81561.1 - 0.16 11.4 12.2 0.21 11.0 12.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Cellulose_synt PF03552.14 RUS81561.1 - 0.19 10.2 7.1 0.25 9.8 7.1 1.1 1 0 0 1 1 1 0 Cellulose synthase FAM91_C PF14648.6 RUS81561.1 - 0.27 10.0 5.6 0.35 9.6 5.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF3807 PF12720.7 RUS81561.1 - 0.28 11.4 20.4 0.38 11.0 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNA_pol_Rpc4 PF05132.14 RUS81561.1 - 0.3 11.5 16.0 0.43 11.0 16.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_pol_Rpb1_5 PF04998.17 RUS81561.1 - 0.3 10.5 6.0 0.37 10.2 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 EMC3_TMCO1 PF01956.16 RUS81561.1 - 0.31 10.7 11.0 0.44 10.3 11.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like GAGA_bind PF06217.12 RUS81561.1 - 0.33 11.2 21.9 0.46 10.7 21.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MAP17 PF15807.5 RUS81561.1 - 0.42 10.8 14.3 0.72 10.1 14.3 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2828 PF11443.8 RUS81561.1 - 0.48 8.4 15.6 0.62 8.1 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) YMF19 PF02326.15 RUS81561.1 - 0.51 11.2 4.9 0.97 10.3 4.9 1.5 1 0 0 1 1 1 0 Plant ATP synthase F0 PPL5 PF18168.1 RUS81561.1 - 0.57 9.4 11.6 0.75 9.0 11.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 OSTbeta PF15048.6 RUS81561.1 - 0.61 10.2 8.6 0.88 9.7 8.6 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DcuA_DcuB PF03605.14 RUS81561.1 - 0.72 8.7 2.0 0.93 8.3 2.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PcfK PF14058.6 RUS81561.1 - 0.8 10.0 25.2 1.4 9.2 25.2 1.3 1 0 0 1 1 1 0 PcfK-like protein RPOL_N PF14700.6 RUS81561.1 - 0.91 8.8 15.3 1.2 8.5 15.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF2126 PF09899.9 RUS81561.1 - 0.94 7.5 4.9 1.2 7.2 4.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EIIBC-GUT_N PF03612.14 RUS81561.1 - 0.95 9.2 11.3 1.6 8.4 11.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RPA43_OB PF17875.1 RUS81561.1 - 0.99 10.0 7.5 1.5 9.5 7.5 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I MDFI PF15316.6 RUS81561.1 - 1.3 9.1 7.9 1.9 8.5 7.9 1.3 1 0 0 1 1 1 0 MyoD family inhibitor DUF2228 PF10228.9 RUS81561.1 - 1.3 8.7 13.8 2.3 7.9 13.8 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) YL1 PF05764.13 RUS81561.1 - 1.3 9.0 28.6 1.7 8.7 28.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Peroxin-13_N PF04088.13 RUS81561.1 - 1.4 9.2 8.6 2.1 8.6 8.6 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Paramyxo_ncap PF00973.19 RUS81561.1 - 1.4 7.7 8.5 1.9 7.3 8.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PRC2_HTH_1 PF18118.1 RUS81561.1 - 1.5 9.6 16.0 2.6 8.9 16.0 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain LicD PF04991.13 RUS81561.1 - 1.6 8.8 16.2 2.1 8.4 16.2 1.1 1 0 0 1 1 1 0 LicD family SspB PF04386.13 RUS81561.1 - 1.9 8.4 8.6 2.8 7.8 8.6 1.3 1 0 0 1 1 1 0 Stringent starvation protein B RR_TM4-6 PF06459.12 RUS81561.1 - 2.3 8.0 20.7 2.9 7.6 20.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IDO PF01231.18 RUS81561.1 - 2.4 6.8 9.8 3.2 6.4 9.8 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF3987 PF13148.6 RUS81561.1 - 2.4 7.1 9.3 2.9 6.8 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Afi1 PF07792.12 RUS81561.1 - 2.5 8.6 10.6 3.6 8.1 10.6 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ureide_permease PF07168.11 RUS81561.1 - 3 6.5 10.6 4.3 6.0 10.6 1.2 1 0 0 1 1 1 0 Ureide permease AIF_C PF14721.6 RUS81561.1 - 3.3 8.1 11.8 5.2 7.4 11.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MAS20 PF02064.15 RUS81561.1 - 3.7 7.7 17.5 6.5 6.9 17.5 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF3464 PF11947.8 RUS81561.1 - 4 7.2 21.7 6.8 6.4 21.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 NARP1 PF12569.8 RUS81561.1 - 4.2 6.2 28.0 5.3 5.8 28.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ALMT PF11744.8 RUS81561.1 - 4.5 6.0 10.9 5.8 5.6 10.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MCM_bind PF09739.9 RUS81561.1 - 5.4 5.3 12.8 6.9 5.0 12.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GNAT_acetyltr_2 PF13718.6 RUS81561.1 - 6.3 6.1 9.2 8.5 5.7 9.2 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Sec62 PF03839.16 RUS81561.1 - 7.5 6.0 23.9 15 5.0 23.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 TAF1D PF15333.6 RUS81561.1 - 8.4 6.1 27.9 13 5.5 27.9 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D MDM10 PF12519.8 RUS81561.1 - 8.9 5.0 11.9 14 4.4 11.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CBM_14 PF01607.24 RUS81564.1 - 9.8e-25 86.5 8.9 7.1e-08 32.5 0.4 3.3 3 0 0 3 3 3 3 Chitin binding Peritrophin-A domain DUF5401 PF17380.2 RUS81564.1 - 0.35 8.9 5.7 1.6 6.7 1.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5401) Med12-LCEWAV PF12145.8 RUS81564.1 - 0.41 9.4 1.1 0.37 9.6 0.2 1.6 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain DUF4215 PF13948.6 RUS81564.1 - 6.3 7.3 8.1 44 4.6 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4215) TTL PF03133.15 RUS81565.1 - 3.1e-49 167.7 2.8 3.1e-49 167.7 2.8 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS81565.1 - 3.8e-11 42.7 0.1 5e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS81565.1 - 0.0023 17.3 0.0 0.086 12.1 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Spt20 PF12090.8 RUS81565.1 - 8.8 5.9 15.9 1.2 8.7 6.2 2.4 2 0 0 2 2 2 0 Spt20 family NLPC_P60 PF00877.19 RUS81566.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NlpC/P60 family PYNP_C PF07831.13 RUS81567.1 - 0.071 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Presenilin PF01080.17 RUS81567.1 - 4.8 5.8 8.3 5.7 5.6 8.3 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 RUS81570.1 - 3.3e-34 118.4 49.5 9.1e-30 103.8 34.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS81570.1 - 1.6e-06 27.2 30.6 6.2e-06 25.3 13.0 3.9 2 2 1 3 3 3 3 MFS_1 like family DUF1600 PF07667.11 RUS81570.1 - 0.52 10.5 5.7 0.21 11.8 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) PIGA PF08288.12 RUS81571.1 - 2.1e-44 150.0 0.3 5.1e-44 148.8 0.3 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RUS81571.1 - 1.3e-29 103.4 0.1 1.9e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RUS81571.1 - 5.9e-23 81.3 0.0 9.8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RUS81571.1 - 5e-19 69.0 0.1 1.3e-18 67.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RUS81571.1 - 3.2e-11 43.9 0.0 5.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 RUS81571.1 - 0.0015 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 RUS81571.1 - 0.0091 16.4 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 RUS81571.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Lig_chan PF00060.26 RUS81573.1 - 8.9e-07 28.8 0.1 1.4e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel MFS_1 PF07690.16 RUS81575.1 - 1.4e-09 37.4 45.9 2.7e-05 23.3 17.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Aminotran_5 PF00266.19 RUS81576.1 - 3.1e-51 174.5 0.0 2.7e-49 168.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V TPR_1 PF00515.28 RUS81577.1 - 9.3e-15 53.7 0.3 0.0052 16.6 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat zf-RING_2 PF13639.6 RUS81577.1 - 1.4e-11 44.6 6.8 1.4e-11 44.6 6.8 2.9 3 0 0 3 3 2 1 Ring finger domain TPR_2 PF07719.17 RUS81577.1 - 3.4e-10 39.2 5.0 0.043 13.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-rbx1 PF12678.7 RUS81577.1 - 4.8e-08 33.2 5.5 4.8e-08 33.2 5.5 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RUS81577.1 - 2.5e-07 30.4 5.2 2.5e-07 30.4 5.2 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS81577.1 - 3.7e-07 29.8 2.2 3.7e-07 29.8 2.2 2.1 2 0 0 2 2 1 1 RING-like zinc finger TPR_19 PF14559.6 RUS81577.1 - 5.5e-07 30.0 0.2 0.018 15.6 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-C3HC4 PF00097.25 RUS81577.1 - 3.9e-06 26.6 4.9 3.9e-06 26.6 4.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS81577.1 - 2.8e-05 24.0 3.1 7.4e-05 22.7 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS81577.1 - 8.1e-05 22.4 4.5 8.1e-05 22.4 4.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 RUS81577.1 - 8.4e-05 22.2 0.1 0.48 10.1 0.1 3.9 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 RUS81577.1 - 0.00016 21.9 2.8 1.9 8.8 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81577.1 - 0.00034 21.2 7.7 0.32 11.7 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat PAM2 PF07145.15 RUS81577.1 - 0.00045 19.7 0.2 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region zf-ANAPC11 PF12861.7 RUS81577.1 - 0.00065 19.7 2.6 0.00065 19.7 2.6 2.1 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RUS81577.1 - 0.00086 19.2 5.7 0.00086 19.2 5.7 2.0 2 0 0 2 2 1 1 zinc-RING finger domain TPR_7 PF13176.6 RUS81577.1 - 0.0035 17.2 1.4 1.8 8.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Sigma70_ner PF04546.13 RUS81577.1 - 0.0042 17.0 13.4 0.0042 17.0 13.4 3.2 3 0 0 3 3 2 1 Sigma-70, non-essential region TPR_14 PF13428.6 RUS81577.1 - 0.0051 17.5 0.3 0.43 11.5 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS81577.1 - 0.011 15.6 2.3 3.9 7.5 0.0 4.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS81577.1 - 0.019 15.1 0.6 1.8 9.0 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 RUS81577.1 - 0.29 10.8 5.3 0.83 9.3 5.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UPF0160 PF03690.13 RUS81577.1 - 0.35 10.5 2.9 0.73 9.4 2.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) ANAPC3 PF12895.7 RUS81577.1 - 0.57 10.4 4.2 0.23 11.7 0.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MitMem_reg PF13012.6 RUS81577.1 - 0.93 9.9 3.9 4.3 7.8 3.9 2.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function APG6_N PF17675.1 RUS81577.1 - 4.5 7.8 39.3 8.8 6.9 23.9 3.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_9 PF13371.6 RUS81577.1 - 4.7 7.4 5.7 7.5 6.8 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat MCC-bdg_PDZ PF10506.9 RUS81578.1 - 1.3e-28 98.8 11.5 5.7e-19 67.9 3.7 6.5 6 1 0 6 6 6 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Rootletin PF15035.6 RUS81578.1 - 0.046 13.8 0.1 0.046 13.8 0.1 5.5 5 1 0 5 5 5 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 RUS81578.1 - 0.089 13.2 21.2 0.32 11.4 0.5 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 RUS81578.1 - 3.6 7.6 34.1 0.19 11.8 2.0 5.1 4 0 0 4 4 4 0 FlxA-like protein DUF4407 PF14362.6 RUS81578.1 - 4.2 6.6 39.8 0.75 9.1 0.6 5.0 3 1 1 5 5 5 0 Domain of unknown function (DUF4407) EF-hand_7 PF13499.6 RUS81579.1 - 5.6e-07 29.9 0.7 1.2e-06 28.9 0.7 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS81579.1 - 1.9e-06 27.0 0.2 3.5e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS81579.1 - 4.1e-06 26.3 0.2 1.1e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RUS81579.1 - 0.0042 16.9 0.3 0.022 14.6 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 RUS81579.1 - 0.013 15.4 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 RUS81579.1 - 0.024 14.1 0.2 0.074 12.6 0.2 1.8 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 RUS81579.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-RING_UBOX PF13445.6 RUS81581.1 - 6.5e-06 26.1 11.0 6.5e-06 26.1 11.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 RUS81581.1 - 7.2e-05 22.9 7.0 7.2e-05 22.9 7.0 3.1 2 1 1 3 3 3 1 B-box zinc finger NHL PF01436.21 RUS81581.1 - 8.5e-05 22.4 0.2 0.0053 16.7 0.1 2.7 2 0 0 2 2 2 1 NHL repeat zf-C3HC4_4 PF15227.6 RUS81581.1 - 0.00017 21.7 12.4 0.00017 21.7 12.4 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RUS81581.1 - 0.00081 19.2 13.7 0.00081 19.2 13.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS81581.1 - 0.00084 19.2 11.0 0.00084 19.2 11.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS81581.1 - 0.0063 16.5 13.1 0.0063 16.5 13.1 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS81581.1 - 0.014 15.7 13.8 0.014 15.7 13.8 2.6 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 RUS81581.1 - 0.022 14.7 1.7 0.022 14.7 1.7 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 MRFAP1 PF15155.6 RUS81581.1 - 0.088 13.3 1.9 0.19 12.2 1.9 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 TNFR_c6 PF00020.18 RUS81582.1 - 4.7e-12 46.1 16.5 5.4e-07 29.9 1.8 3.6 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS81582.1 - 0.00062 19.5 15.6 0.007 16.1 5.9 3.4 1 1 2 3 3 3 2 Putative ephrin-receptor like NCD3G PF07562.14 RUS81582.1 - 3.1 7.8 17.5 2.4 8.2 3.5 3.0 2 2 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ammonium_transp PF00909.21 RUS81585.1 - 9.1e-45 153.0 14.9 1.1e-44 152.7 14.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 RUS81586.1 - 0.024 13.3 0.0 0.029 13.1 0.0 1.0 1 0 0 1 1 1 0 Ammonium Transporter Family Lipase_GDSL_2 PF13472.6 RUS81587.1 - 8.2e-08 32.8 0.0 1.1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 RUS81587.1 - 0.0072 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family c-SKI_SMAD_bind PF08782.10 RUS81588.1 - 8.3e-06 25.9 0.2 2.1e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 c-SKI Smad4 binding domain YL1 PF05764.13 RUS81588.1 - 0.0046 17.1 4.2 0.0046 17.1 4.2 2.7 2 1 0 2 2 2 1 YL1 nuclear protein Roughex PF06020.11 RUS81588.1 - 0.25 10.4 5.5 0.53 9.3 5.5 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Astro_capsid_p PF12226.8 RUS81588.1 - 0.38 9.9 5.8 0.7 9.0 5.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MAJIN PF15077.6 RUS81588.1 - 0.47 10.2 9.9 1.1 9.0 9.9 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein NARP1 PF12569.8 RUS81588.1 - 3.1 6.6 11.2 4.9 6.0 11.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ski_Sno PF02437.17 RUS81589.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-HC5HC2H_2 PF13832.6 RUS81591.1 - 6.5e-29 100.3 27.2 1.3e-28 99.3 17.1 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RUS81591.1 - 2.5e-19 69.3 14.6 2.5e-19 69.3 14.6 3.4 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 RUS81591.1 - 8.2e-14 50.9 2.9 8.2e-14 50.9 2.9 2.8 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 RUS81591.1 - 1e-08 34.9 8.8 1e-08 34.9 8.8 3.3 3 1 0 3 3 3 2 PHD-finger zf-RING-like PF08746.11 RUS81591.1 - 9 6.7 16.6 2.4 8.5 3.9 3.4 2 1 0 2 2 2 0 RING-like domain Thiolase_N PF00108.23 RUS81592.1 - 1.2e-64 218.2 0.1 1.5e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS81592.1 - 1.3e-47 160.5 1.6 1.4e-47 160.4 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 RUS81592.1 - 0.0001 22.4 0.0 0.00038 20.6 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 RUS81592.1 - 0.044 13.6 0.5 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 RUS81593.1 - 1e-11 44.7 0.1 7.9e-10 38.5 0.0 3.2 3 1 0 3 3 3 1 Ubiquitin-conjugating enzyme Zip PF02535.22 RUS81594.1 - 3.6e-47 161.2 2.1 4.7e-47 160.8 2.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter zf-met2 PF12907.7 RUS81594.1 - 0.21 11.7 1.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding Colipase_C PF02740.14 RUS81595.1 - 0.83 9.9 8.1 1.3 9.3 4.8 2.8 2 1 0 2 2 2 0 Colipase, C-terminal domain Nodulin_late PF07127.11 RUS81595.1 - 4.2 7.8 7.5 0.78 10.1 1.0 2.4 2 1 0 2 2 2 0 Late nodulin protein Neur_chan_LBD PF02931.23 RUS81596.1 - 5.3e-54 182.9 2.9 7.2e-54 182.5 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS81596.1 - 1.3e-35 123.6 0.3 2e-35 123.0 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Mlf1IP PF10248.9 RUS81597.1 - 1.3e-12 48.0 5.1 8.1e-11 42.2 1.0 2.3 2 0 0 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF4834 PF16118.5 RUS81597.1 - 0.054 14.4 1.0 0.72 10.8 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) 7tm_1 PF00001.21 RUS81598.1 - 2.5e-38 131.9 26.0 3.2e-38 131.6 26.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS81598.1 - 2e-06 27.7 19.5 2e-06 27.7 19.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Sulfotransfer_3 PF13469.6 RUS81600.1 - 6.6e-05 23.4 0.0 0.00022 21.7 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS81600.1 - 0.00019 21.0 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain F-box PF00646.33 RUS81601.1 - 3.5e-07 29.9 0.0 7.9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS81601.1 - 0.00025 20.9 0.2 0.00087 19.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like PARP PF00644.20 RUS81602.1 - 2.3e-19 69.7 0.0 5.8e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UBA_4 PF14555.6 RUS81602.1 - 1.2e-05 25.0 0.0 0.00037 20.3 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain ART-PolyVal PF18760.1 RUS81602.1 - 0.049 14.7 0.8 0.23 12.5 0.5 2.4 1 1 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins Arrestin_N PF00339.29 RUS81603.1 - 9.2e-36 123.1 0.0 5.1e-34 117.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS81603.1 - 2.2e-23 83.2 0.0 4.1e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 RUS81603.1 - 0.057 12.4 0.1 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 TPR_2 PF07719.17 RUS81604.1 - 5.6e-33 110.4 34.5 0.00038 20.4 0.0 19.0 21 0 0 21 21 18 7 Tetratricopeptide repeat TPR_14 PF13428.6 RUS81604.1 - 5.1e-32 107.8 25.7 8.9e-05 23.0 0.5 17.4 15 3 4 19 19 15 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81604.1 - 1.1e-31 109.1 8.3 2.7e-05 24.7 0.1 11.5 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 RUS81604.1 - 3.4e-29 101.2 33.9 4.5e-05 23.9 0.1 14.2 13 2 3 16 16 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 RUS81604.1 - 1.5e-28 97.4 31.9 0.0001 22.0 0.0 16.5 17 0 0 17 17 17 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS81604.1 - 6.7e-27 91.4 37.8 0.015 15.5 0.0 17.8 19 0 0 19 19 16 7 Tetratricopeptide repeat TPR_17 PF13431.6 RUS81604.1 - 3.4e-19 67.8 15.4 3.3e-05 24.0 0.0 14.7 17 0 0 17 17 15 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS81604.1 - 3.7e-17 62.4 26.1 0.029 14.6 0.2 13.1 11 1 4 15 15 13 4 Tetratricopeptide repeat TPR_11 PF13414.6 RUS81604.1 - 1.1e-14 53.8 16.9 0.051 13.3 0.0 13.5 13 2 3 16 16 16 4 TPR repeat ANAPC3 PF12895.7 RUS81604.1 - 1.6e-11 44.2 39.1 0.062 13.5 0.3 10.7 9 3 2 12 12 11 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RUS81604.1 - 9.9e-09 34.6 8.1 0.092 12.8 0.0 10.5 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS81604.1 - 9.8e-08 32.0 11.1 0.39 10.9 0.0 8.5 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS81604.1 - 1.8e-07 31.3 19.5 21 6.0 0.1 12.5 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS81604.1 - 4.3e-05 22.9 19.5 0.00041 19.6 2.1 6.6 4 3 1 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 RUS81604.1 - 0.00045 20.0 5.3 7.7 6.2 0.1 5.0 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Coatomer_WDAD PF04053.14 RUS81604.1 - 0.00054 19.1 0.4 0.7 8.9 0.0 2.7 2 0 0 2 2 2 2 Coatomer WD associated region SRP_TPR_like PF17004.5 RUS81604.1 - 0.001 19.1 10.9 0.0012 18.8 0.7 4.4 3 2 2 5 5 5 1 Putative TPR-like repeat Alkyl_sulf_dimr PF14863.6 RUS81604.1 - 0.0012 19.3 8.5 6.3 7.2 0.2 4.9 4 1 1 5 5 4 1 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 RUS81604.1 - 0.0018 18.3 1.9 0.23 11.6 0.0 4.6 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 RUS81604.1 - 0.0032 16.9 16.0 0.0045 16.5 0.4 5.4 4 2 1 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 RUS81604.1 - 0.0054 16.6 4.2 19 5.3 0.0 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat BTAD PF03704.17 RUS81604.1 - 0.011 16.2 11.0 0.42 11.0 0.2 6.3 4 2 2 6 6 6 0 Bacterial transcriptional activator domain ChAPs PF09295.10 RUS81604.1 - 0.013 14.6 17.1 0.55 9.2 0.4 6.5 4 2 2 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) Vps39_1 PF10366.9 RUS81604.1 - 0.071 13.4 1.8 3.4 8.0 0.1 4.2 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 1 TPR_20 PF14561.6 RUS81604.1 - 0.19 12.1 20.3 0.61 10.5 0.2 7.2 9 0 0 9 9 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RUS81604.1 - 0.27 10.9 10.1 14 5.3 0.0 6.3 7 2 0 7 7 7 0 Bacterial type III secretion protein (HrpB1_HrpK) Telomere_reg-2 PF10193.9 RUS81604.1 - 0.73 10.3 7.0 18 5.8 0.0 4.9 4 1 0 4 4 4 0 Telomere length regulation protein PPR PF01535.20 RUS81604.1 - 9.7 6.7 6.9 26 5.4 0.0 5.2 6 0 0 6 6 3 0 PPR repeat BCIP PF13862.6 RUS81605.1 - 1.6e-51 175.0 1.6 2.8e-51 174.3 1.6 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Baculo_p24 PF05073.12 RUS81605.1 - 0.0041 16.9 0.9 0.007 16.2 0.9 1.3 1 0 0 1 1 1 1 Baculovirus P24 capsid protein DUF4611 PF15387.6 RUS81605.1 - 0.017 15.3 9.1 0.017 15.3 9.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) CbiG_mid PF11761.8 RUS81605.1 - 0.072 13.2 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 Cobalamin biosynthesis central region Spt5_N PF11942.8 RUS81605.1 - 0.13 13.3 10.2 0.38 11.8 2.0 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Treacle PF03546.14 RUS81605.1 - 0.35 9.6 0.9 0.59 8.9 0.9 1.2 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle SDA1 PF05285.12 RUS81605.1 - 0.47 9.8 6.1 0.63 9.4 6.1 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 RUS81605.1 - 1.2 8.8 5.4 1.4 8.6 0.8 2.4 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 RUS81605.1 - 1.6 8.8 8.8 0.16 12.0 1.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 RUS81605.1 - 6.9 5.9 12.3 3.5 6.9 7.9 2.0 2 0 0 2 2 2 0 BUD22 MOZ_SAS PF01853.18 RUS81606.1 - 1.1e-85 285.8 0.7 1.9e-85 285.0 0.7 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RUS81606.1 - 6.8e-22 76.8 3.7 6.8e-22 76.8 3.7 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2HC PF01530.18 RUS81606.1 - 7.9e-11 41.9 8.4 1.9e-10 40.8 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 RUS81606.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPATA48 PF15073.6 RUS81606.1 - 0.072 13.4 1.6 0.25 11.6 0.0 2.5 2 1 0 2 2 2 0 Spermatogenesis-associated protein 48 C1ORF64 PF15547.6 RUS81606.1 - 1.2 9.6 4.1 3.1 8.3 4.1 1.6 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein PPI_Ypi1 PF07491.11 RUS81606.1 - 7.1 6.6 9.6 0.26 11.1 2.3 2.5 2 0 0 2 2 2 0 Protein phosphatase inhibitor Myosin_head PF00063.21 RUS81607.1 - 4.8e-251 834.8 4.8 5.8e-251 834.5 4.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RUS81607.1 - 8.4e-51 172.3 0.6 1.8e-50 171.3 0.6 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 RUS81607.1 - 2.2e-16 59.4 0.2 1.1e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RUS81607.1 - 7.2e-16 57.5 0.9 1.8e-15 56.2 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RUS81607.1 - 6.6e-11 41.7 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RsgA_GTPase PF03193.16 RUS81607.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 RUS81607.1 - 0.07 13.6 0.2 0.29 11.6 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 RUS81607.1 - 0.094 13.0 0.1 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RUS81607.1 - 0.12 12.8 0.0 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_2 PF03668.15 RUS81607.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family Sigma54_activat PF00158.26 RUS81607.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Nop PF01798.18 RUS81608.1 - 1.4e-86 289.7 0.0 1.4e-86 289.7 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RUS81608.1 - 9.3e-17 61.2 0.3 9.3e-17 61.2 0.3 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SWI-SNF_Ssr4 PF08549.10 RUS81608.1 - 1.2 7.7 16.9 1.5 7.3 16.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Peptidase_M54 PF07998.11 RUS81609.1 - 5e-08 33.2 1.1 2e-07 31.2 1.0 1.9 1 1 0 1 1 1 1 Peptidase family M54 Oxidored_q6 PF01058.22 RUS81610.1 - 2.6e-23 82.3 0.1 3.6e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NUDIX PF00293.28 RUS81612.1 - 4.3e-19 68.8 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 RUS81612.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain p450 PF00067.22 RUS81613.1 - 6.6e-35 120.7 0.0 1.5e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ApeC PF16977.5 RUS81615.1 - 4.5e-42 144.3 0.4 4.5e-42 144.3 0.4 2.8 3 0 0 3 3 3 1 C-terminal domain of apextrin Lectin_C PF00059.21 RUS81615.1 - 2.4e-37 128.0 0.2 8.3e-20 71.5 0.1 2.9 2 0 0 2 2 2 2 Lectin C-type domain Astacin PF01400.24 RUS81615.1 - 1.5e-22 80.2 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kringle PF00051.18 RUS81615.1 - 2.6e-13 50.1 6.7 1.1e-12 48.0 6.7 2.2 1 0 0 1 1 1 1 Kringle domain CUB PF00431.20 RUS81615.1 - 1.9e-08 34.6 0.0 6.1e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 RUS81615.1 - 7.5e-06 26.4 2.9 0.0031 18.1 1.5 3.4 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Reprolysin_3 PF13582.6 RUS81615.1 - 0.053 14.0 0.4 0.11 13.0 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like C6_DPF PF10170.9 RUS81616.1 - 4.4e-05 23.8 15.0 11 6.5 0.1 6.2 1 1 5 6 6 6 5 Cysteine-rich domain OST_IS PF18246.1 RUS81616.1 - 0.031 14.5 1.6 73 3.8 0.0 3.7 1 1 5 6 6 6 0 Oligosaccharyltransferase Insert domain PRMT5_C PF17286.2 RUS81616.1 - 1.6 8.6 5.3 50 3.7 0.8 3.6 1 1 0 2 2 2 0 PRMT5 oligomerisation domain Hpre_diP_synt_I PF07456.11 RUS81616.1 - 2.8 8.0 9.4 24 4.9 1.0 2.7 1 1 3 4 4 4 0 Heptaprenyl diphosphate synthase component I SDF PF00375.18 RUS81617.1 - 1.4e-99 333.8 27.0 1.6e-99 333.6 27.0 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Cue1_U7BR PF18499.1 RUS81618.1 - 0.15 12.2 4.8 1.1 9.4 4.8 2.3 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 DUF716 PF04819.12 RUS81619.1 - 5e-25 87.7 8.3 5e-25 87.7 8.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF716) BUD22 PF09073.10 RUS81620.1 - 0.0024 17.3 17.0 0.0024 17.3 17.0 3.3 3 0 0 3 3 3 1 BUD22 TSC22 PF01166.18 RUS81620.1 - 3.7 7.9 8.8 2.4 8.5 0.7 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Tubulin PF00091.25 RUS81621.1 - 3e-66 223.4 0.0 4.1e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS81621.1 - 6.8e-52 174.9 0.0 1.1e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS81621.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Nucleos_tra2_C PF07662.13 RUS81622.1 - 2.7e-45 154.8 8.3 3.2e-44 151.2 2.5 2.4 2 0 0 2 2 2 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS81622.1 - 2.3e-18 66.5 1.0 2.3e-18 66.5 1.0 3.7 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Vma12 PF11712.8 RUS81622.1 - 0.31 11.1 1.0 9.9 6.2 0.1 3.3 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Nucleos_tra2_C PF07662.13 RUS81623.1 - 7.9e-44 150.0 1.0 7.9e-44 150.0 1.0 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS81623.1 - 2.5e-17 63.2 1.4 2.5e-17 63.2 1.4 3.6 6 0 0 6 6 6 1 Na+ dependent nucleoside transporter N-terminus VIR_N PF15912.5 RUS81623.1 - 0.16 11.6 7.7 0.33 10.5 7.7 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Syndecan PF01034.20 RUS81623.1 - 2.2 8.2 8.5 0.54 10.2 1.0 3.5 3 0 0 3 3 3 0 Syndecan domain SUIM_assoc PF16619.5 RUS81624.1 - 0.018 15.1 3.9 0.018 15.1 3.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 RUS81624.1 - 6 5.9 13.1 0.038 13.2 3.7 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Auxin_repressed PF05564.12 RUS81626.1 - 2 9.1 11.9 0.055 14.2 2.3 2.5 2 0 0 2 2 2 0 Dormancy/auxin associated protein Forkhead PF00250.18 RUS81627.1 - 1.3e-33 115.1 0.0 2.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain MRC1 PF09444.10 RUS81627.1 - 8.4 6.9 7.2 2.6 8.5 0.0 2.9 3 0 0 3 3 3 0 MRC1-like domain G-patch PF01585.23 RUS81628.1 - 7.9e-13 48.1 0.4 1.8e-12 46.9 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RUS81628.1 - 0.0061 16.6 0.7 0.0061 16.6 0.7 4.0 5 0 0 5 5 5 1 G-patch domain CARD PF00619.21 RUS81630.1 - 2.9e-12 46.4 0.2 2.9e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 RUS81630.1 - 1.2e-08 34.8 0.1 4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Caspase recruitment domain CENP-Q PF13094.6 RUS81630.1 - 5.7 7.1 16.0 14 5.9 16.0 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_1 PF00515.28 RUS81631.1 - 1.1e-20 72.5 0.8 2.5e-06 27.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS81631.1 - 7.3e-16 56.9 0.8 5.4e-05 23.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS81631.1 - 2e-12 47.2 0.3 3.7e-09 36.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS81631.1 - 1.1e-11 44.2 0.6 0.0056 16.3 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 RUS81631.1 - 3.1e-10 39.4 1.9 0.00014 21.7 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81631.1 - 4.6e-08 33.6 0.1 0.00017 22.1 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS81631.1 - 1.3e-07 32.0 3.4 2.8e-06 27.7 4.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS81631.1 - 4e-07 30.1 2.0 1.9e-06 27.9 1.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS81631.1 - 7.3e-06 26.4 2.1 0.045 14.6 0.5 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS81631.1 - 3e-05 23.7 0.8 0.44 10.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS81631.1 - 3.4e-05 24.2 0.5 0.005 17.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RUS81631.1 - 0.0003 20.1 1.3 0.0025 17.1 0.4 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 RUS81631.1 - 0.00094 19.3 0.9 0.42 10.7 0.9 3.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 RUS81631.1 - 0.0016 18.7 1.4 0.17 12.3 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RUS81631.1 - 0.0079 15.6 2.3 1.2 8.6 0.0 3.7 4 0 0 4 4 4 1 SHNi-TPR MG2 PF01835.19 RUS81631.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 MG2 domain ANAPC3 PF12895.7 RUS81631.1 - 0.13 12.5 2.7 0.25 11.6 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 RUS81631.1 - 0.18 11.7 0.6 5.6 7.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 RUS81631.1 - 0.33 10.9 6.2 0.18 11.7 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) MIT PF04212.18 RUS81631.1 - 1.5 8.9 8.0 4.2 7.5 0.1 3.4 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain Dimer_Tnp_hAT PF05699.14 RUS81632.1 - 7.5e-05 22.5 0.2 0.00019 21.2 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_1 PF03184.19 RUS81635.1 - 1.9e-16 60.2 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.9 RUS81635.1 - 1.1e-14 54.6 0.6 4.7e-14 52.6 0.1 2.3 3 0 0 3 3 3 1 MULE transposase domain DDE_3 PF13358.6 RUS81635.1 - 1.1e-09 38.2 0.1 3.3e-05 23.7 0.1 2.8 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_psq PF05225.16 RUS81635.1 - 4.6e-07 29.5 0.1 1.2e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Nmad2 PF18753.1 RUS81635.1 - 0.034 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 LIM PF00412.22 RUS81636.1 - 3.9e-24 84.6 24.4 2.1e-13 50.3 7.0 2.1 2 0 0 2 2 2 2 LIM domain DUF2616 PF11077.8 RUS81636.1 - 0.0077 16.0 10.0 0.2 11.4 1.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2616) zf_UBZ PF18439.1 RUS81636.1 - 0.63 9.7 27.1 0.52 9.9 1.0 5.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 RUS81636.1 - 1.5 8.4 13.0 13 5.4 0.3 4.2 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) DUF4428 PF14471.6 RUS81636.1 - 1.7 8.6 15.0 0.62 10.0 0.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) Zn-ribbon_8 PF09723.10 RUS81636.1 - 2.4 8.3 23.5 1.8 8.8 2.8 4.1 3 1 1 4 4 4 0 Zinc ribbon domain HALZ PF02183.18 RUS81638.1 - 0.042 14.1 0.9 0.45 10.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 RUS81638.1 - 0.18 12.3 0.1 0.18 12.3 0.1 2.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.6 RUS81638.1 - 0.31 11.4 3.0 0.68 10.3 1.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PriC PF07445.12 RUS81638.1 - 0.86 9.5 8.0 0.16 11.9 1.5 2.3 2 1 0 2 2 2 0 Primosomal replication protein priC LPP PF04728.13 RUS81638.1 - 8.5 6.9 12.7 0.6 10.5 1.1 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper CD225 PF04505.12 RUS81639.1 - 1.5e-16 60.3 3.7 2.5e-16 59.6 3.7 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 RUS81639.1 - 0.0027 17.4 6.8 0.0093 15.7 6.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) DUF5336 PF17270.2 RUS81639.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Srg PF02118.21 RUS81639.1 - 0.021 14.5 1.2 0.027 14.1 1.2 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor Phage_holin_5_2 PF16079.5 RUS81639.1 - 0.13 12.6 5.9 0.38 11.1 5.9 1.8 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V TFIIA PF03153.13 RUS81640.1 - 4.7 7.1 10.3 5.3 6.9 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S21 PF01165.20 RUS81642.1 - 1.4e-13 50.3 1.4 2.1e-13 49.8 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Nsp1_C PF05064.13 RUS81645.1 - 1.5e-32 111.8 6.4 1.5e-32 111.8 6.4 2.3 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF4164 PF13747.6 RUS81645.1 - 0.0093 16.2 6.9 0.041 14.1 0.3 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) FapA PF03961.13 RUS81645.1 - 0.17 10.5 3.7 0.25 9.9 3.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 RUS81645.1 - 0.22 11.5 12.5 0.54 10.3 4.4 2.6 1 1 0 2 2 2 0 Laminin Domain II ECH_2 PF16113.5 RUS81645.1 - 0.35 10.3 3.3 0.4 10.1 2.7 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MutS_III PF05192.18 RUS81645.1 - 0.8 9.9 5.9 0.34 11.1 3.5 1.5 1 1 1 2 2 2 0 MutS domain III NPV_P10 PF05531.12 RUS81645.1 - 3.8 8.0 15.1 1.9 9.0 3.2 3.4 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MobC PF05713.11 RUS81645.1 - 3.9 8.0 7.0 23 5.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) DUF1664 PF07889.12 RUS81645.1 - 5.1 7.1 12.3 9 6.4 2.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4665 PF15679.5 RUS81645.1 - 5.8 7.6 9.0 19 6.0 0.5 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4665) LMBR1 PF04791.16 RUS81645.1 - 6.3 5.6 7.7 33 3.2 7.7 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein Tropomyosin_1 PF12718.7 RUS81645.1 - 6.6 6.9 17.1 0.28 11.3 7.1 2.7 2 1 0 3 3 3 0 Tropomyosin like DUF16 PF01519.16 RUS81645.1 - 10 6.7 13.6 8.9e+02 0.4 13.6 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 F-box PF00646.33 RUS81646.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS81646.1 - 0.00042 20.1 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2970 PF11174.8 RUS81648.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) THAP PF05485.12 RUS81649.1 - 2.3e-13 50.9 0.2 4.6e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 THAP domain 7tm_3 PF00003.22 RUS81651.1 - 6.1e-58 196.3 16.7 9.3e-58 195.8 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 RUS81651.1 - 1.6e-50 172.2 0.0 2.4e-34 119.0 0.0 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS81651.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein DUF5305 PF17231.2 RUS81651.1 - 0.11 11.9 0.0 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) UPF0242 PF06785.11 RUS81651.1 - 0.18 11.9 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 RUS81651.1 - 0.25 11.4 1.2 0.45 10.6 1.2 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF3671 PF12420.8 RUS81651.1 - 0.64 10.1 4.9 3.1 7.9 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function PRP3 PF08572.10 RUS81653.1 - 6.7e-77 258.2 8.5 6.7e-77 258.2 8.5 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 RUS81653.1 - 2.3e-43 147.8 0.3 2.3e-43 147.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PWI PF01480.17 RUS81653.1 - 0.0005 20.3 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 PWI domain DUF2393 PF09624.10 RUS81653.1 - 0.086 12.8 0.4 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) G_path_suppress PF15991.5 RUS81654.1 - 7.8e-45 154.2 63.4 9e-45 154.0 22.0 3.0 1 1 2 3 3 3 2 G-protein pathway suppressor Allexi_40kDa PF05549.11 RUS81654.1 - 1.1 8.8 7.2 2.8 7.4 7.2 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein YjcZ PF13990.6 RUS81654.1 - 2.4 7.4 8.4 4.4 6.6 8.4 1.4 1 0 0 1 1 1 0 YjcZ-like protein Spore_YhaL PF14147.6 RUS81654.1 - 3.2 7.5 6.4 8 6.2 6.4 1.7 1 0 0 1 1 1 0 Sporulation protein YhaL Hid1 PF12722.7 RUS81654.1 - 3.4 5.7 8.3 5.6 5.0 8.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 RUS81654.1 - 4.3 6.0 9.4 7.6 5.2 9.4 1.4 1 0 0 1 1 1 0 Presenilin MIF4G_like_2 PF09090.11 RUS81654.1 - 7.7 5.9 12.5 15 5.0 12.5 1.4 1 0 0 1 1 1 0 MIF4G like Spc7 PF08317.11 RUS81654.1 - 8.4 5.2 24.7 14 4.4 24.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TRAUB PF08164.12 RUS81655.1 - 2.3e-26 92.1 2.8 1.1e-25 89.9 2.8 2.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 RUS81655.1 - 1.4e-24 87.3 9.9 1.4e-24 87.3 9.9 4.3 3 3 0 3 3 3 1 Apoptosis antagonizing transcription factor Lectin_C PF00059.21 RUS81656.1 - 3.5e-09 37.3 0.2 1e-08 35.9 0.0 1.8 2 0 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 RUS81656.1 - 7.5e-05 22.6 0.5 0.0002 21.3 0.5 1.7 1 0 0 1 1 1 1 PAN domain SprT-like PF10263.9 RUS81656.1 - 0.17 11.7 0.1 0.35 10.8 0.1 1.4 1 1 0 1 1 1 0 SprT-like family Lectin_C PF00059.21 RUS81657.1 - 4.5e-13 49.9 0.2 7.8e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.15 RUS81657.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF333) CgtA PF06306.11 RUS81658.1 - 0.06 12.8 0.2 2.9 7.2 0.0 1.8 1 1 1 2 2 2 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) QVR PF17064.5 RUS81659.1 - 0.00046 20.4 11.2 0.0014 18.8 2.9 2.3 2 0 0 2 2 2 2 Sleepless protein DUF1858 PF08984.11 RUS81659.1 - 0.096 12.9 0.2 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) A_deaminase PF00962.22 RUS81660.1 - 2.5e-06 27.1 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase KIAA1430 PF13879.6 RUS81661.1 - 0.0032 18.2 0.0 0.0075 17.0 0.0 1.6 1 1 0 1 1 1 1 KIAA1430 homologue DUF3641 PF12345.8 RUS81661.1 - 0.056 13.5 0.1 0.24 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) Ribosomal_L11_N PF03946.14 RUS81665.1 - 1.7e-19 69.4 0.2 2.7e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RUS81665.1 - 1.1e-17 64.3 0.7 1.8e-17 63.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Topoisom_bac PF01131.20 RUS81667.1 - 1.6e-111 373.3 0.0 1.9e-111 373.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 RUS81667.1 - 1.9e-16 60.2 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain SelK_SelG PF10961.8 RUS81667.1 - 0.13 12.8 3.7 28 5.4 0.0 2.6 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RhlB PF12300.8 RUS81667.1 - 3.2 7.8 6.5 5.7 7.1 6.5 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB SNARE PF05739.19 RUS81668.1 - 0.00051 20.0 0.1 0.00093 19.1 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Orf78 PF06024.12 RUS81668.1 - 0.07 13.4 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF4211 PF13926.6 RUS81669.1 - 1.2e-12 48.1 0.0 3.1e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) WHIM1 PF15612.6 RUS81670.1 - 0.001 18.5 0.0 0.003 17.0 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 RUS81670.1 - 0.0012 19.1 0.2 0.0029 17.9 0.2 1.6 1 0 0 1 1 1 1 DDT domain pKID PF02173.17 RUS81671.1 - 8.3 6.0 9.4 0.4 10.2 1.7 2.8 3 0 0 3 3 3 0 pKID domain Bromodomain PF00439.25 RUS81672.1 - 1.4e-19 69.9 0.2 2.7e-19 69.0 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Fucose_iso_N2 PF07882.12 RUS81672.1 - 0.5 9.9 3.4 0.14 11.7 0.3 1.6 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain NOA36 PF06524.12 RUS81672.1 - 2.5 7.3 6.8 4.1 6.7 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein IRS PF02174.17 RUS81675.1 - 7.2e-11 41.9 0.1 1.9e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 RUS81675.1 - 0.039 14.5 2.1 0.086 13.4 0.3 2.6 2 1 0 2 2 2 0 PH domain NEMO PF11577.8 RUS81675.1 - 0.085 12.9 0.9 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO PH_11 PF15413.6 RUS81675.1 - 3.9 7.9 6.4 9.9 6.6 2.7 3.4 2 2 0 2 2 2 0 Pleckstrin homology domain Sulfotransfer_2 PF03567.14 RUS81676.1 - 1.1e-26 94.3 0.1 2.3e-24 86.7 0.0 2.7 2 1 0 2 2 2 2 Sulfotransferase family Mod_r PF07200.13 RUS81676.1 - 0.0077 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Ion_trans_2 PF07885.16 RUS81677.1 - 3.6e-37 126.2 13.8 1.6e-18 66.4 0.2 3.1 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS81677.1 - 4.6e-06 26.1 8.3 0.011 14.9 3.1 2.4 2 1 0 2 2 2 2 Ion transport protein Shisa PF13908.6 RUS81677.1 - 0.012 15.9 0.9 0.034 14.4 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4518 PF15008.6 RUS81678.1 - 8.5e-65 218.6 0.7 1.1e-64 218.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) TMEM70 PF06979.12 RUS81679.1 - 2.5e-08 34.4 0.0 3.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Knl1_RWD_C PF18210.1 RUS81680.1 - 0.027 14.9 0.1 0.1 13.1 0.1 2.0 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain Sec34 PF04136.15 RUS81680.1 - 0.54 10.1 8.8 0.4 10.6 1.3 3.4 1 1 2 3 3 3 0 Sec34-like family DUF3116 PF11313.8 RUS81680.1 - 9.1 6.2 7.2 25 4.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3116) Gcd10p PF04189.13 RUS81681.1 - 1.2e-58 198.6 0.3 1.6e-58 198.2 0.3 1.2 1 0 0 1 1 1 1 Gcd10p family Acetyltransf_1 PF00583.25 RUS81682.1 - 2.1e-08 34.4 0.0 2.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS81682.1 - 4.2e-08 33.5 0.1 5.8e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS81682.1 - 1.7e-06 28.0 0.1 2.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RUS81682.1 - 0.00014 22.0 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS81682.1 - 0.018 15.0 0.2 0.044 13.7 0.2 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 RUS81682.1 - 0.051 13.6 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 RUS81683.1 - 4.6e-08 32.9 0.0 9.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cNMP_binding PF00027.29 RUS81684.1 - 3.1e-33 113.7 0.2 2.5e-14 53.1 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 RUS81684.1 - 7.2e-18 65.5 2.9 1.8e-15 57.7 2.9 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase PRA1 PF03208.19 RUS81684.1 - 0.84 9.3 10.3 2.2 7.9 10.3 1.7 1 0 0 1 1 1 0 PRA1 family protein Nop14 PF04147.12 RUS81684.1 - 4 5.5 19.4 5.6 5.1 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 RUS81684.1 - 7 5.9 16.5 12 5.0 16.5 1.3 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 RUS81684.1 - 9.2 6.2 25.5 15 5.5 25.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Meleagrin PF08189.11 RUS81685.1 - 1.4 8.7 20.5 10 5.9 0.1 7.8 6 2 3 9 9 9 0 Meleagrin/Cygnin family NiFe_hyd_3_EhaA PF17367.2 RUS81685.1 - 1.7 8.8 10.0 9.3 6.5 0.1 5.4 2 1 3 5 5 5 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF282 PF03380.14 RUS81688.1 - 0.42 10.6 11.4 9.3 6.3 0.7 4.5 4 1 0 4 4 4 0 Caenorhabditis protein of unknown function, DUF282 PRP38 PF03371.15 RUS81689.1 - 1.7e-54 184.3 0.0 2.5e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Urm1 PF09138.11 RUS81690.1 - 6.6e-39 132.2 0.0 7.3e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 RUS81690.1 - 0.00026 21.6 0.0 0.00032 21.3 0.0 1.2 1 0 0 1 1 1 1 ThiS family Iso_dh PF00180.20 RUS81691.1 - 4.9e-62 210.1 0.0 6e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4955 PF16315.5 RUS81691.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) DNA_pol_phi PF04931.13 RUS81692.1 - 0.24 9.5 10.7 0.37 8.8 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 RUS81692.1 - 0.43 8.3 11.4 0.57 7.9 11.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF572 PF04502.13 RUS81692.1 - 0.51 9.9 13.2 0.84 9.2 13.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Y_phosphatase PF00102.27 RUS81693.1 - 1.6e-119 397.7 0.0 9.4e-64 215.2 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 RUS81693.1 - 1.2e-06 28.4 0.1 0.04 13.7 0.0 2.6 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS81693.1 - 0.00038 20.5 0.0 0.085 12.8 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family fn3 PF00041.21 RUS81693.1 - 0.0007 19.9 0.0 1.2 9.6 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain SKG6 PF08693.10 RUS81693.1 - 0.0015 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Myotub-related PF06602.14 RUS81693.1 - 0.0096 14.9 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain DUF2207 PF09972.9 RUS81693.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LAX PF15681.5 RUS81693.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X Syndecan PF01034.20 RUS81693.1 - 0.038 13.9 0.2 0.082 12.8 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 RUS81693.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RUS81693.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PTP_tm PF18861.1 RUS81693.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Y_phosphatase2 PF03162.13 RUS81693.1 - 0.17 11.5 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Stevor PF17410.2 RUS81693.1 - 0.19 11.2 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3377 PF11857.8 RUS81693.1 - 0.28 11.1 0.9 0.52 10.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) fn3 PF00041.21 RUS81694.1 - 4.3e-33 113.5 5.3 3.1e-08 33.8 0.0 6.0 6 0 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS81694.1 - 4e-07 30.5 10.0 0.0023 18.5 0.7 5.3 4 2 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 RUS81694.1 - 3.7e-06 27.1 3.1 0.41 10.9 0.4 4.0 4 0 0 4 4 4 2 SusE outer membrane protein Big_5 PF13205.6 RUS81694.1 - 0.044 14.5 8.7 0.24 12.1 1.1 3.8 3 1 1 4 4 4 0 Bacterial Ig-like domain DUF2808 PF10989.8 RUS81694.1 - 0.12 12.4 0.7 1.2 9.1 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2808) SRCR PF00530.18 RUS81695.1 - 6e-38 129.4 0.6 1.2e-19 70.7 0.5 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 RUS81695.1 - 9.2e-36 123.9 7.0 9.2e-36 123.9 7.0 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain SRCR_2 PF15494.6 RUS81695.1 - 9.4e-09 35.7 5.3 0.00054 20.5 0.1 3.6 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS81695.1 - 0.25 11.9 2.9 26 5.4 0.0 3.3 4 0 0 4 4 4 0 Hepsin, SRCR domain Apt1 PF10351.9 RUS81695.1 - 6.4 5.5 6.2 8.9 5.0 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Kelch_1 PF01344.25 RUS81696.1 - 5.4e-90 294.8 14.9 1.8e-15 56.2 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS81696.1 - 4.2e-51 169.7 6.2 1e-08 35.1 0.0 6.3 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 RUS81696.1 - 1.8e-35 121.2 0.1 3.7e-35 120.1 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 RUS81696.1 - 9.6e-31 106.3 1.2 9.6e-31 106.3 1.2 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 RUS81696.1 - 1.5e-29 101.8 5.5 0.00011 22.1 0.0 6.3 2 2 4 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS81696.1 - 7.3e-28 96.3 10.3 1.2e-06 28.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS81696.1 - 4e-27 93.1 6.0 0.00011 22.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 RUS81696.1 - 1.4e-06 28.2 0.4 0.26 11.3 0.0 5.1 5 0 0 5 5 5 1 Kelch motif DUF2963 PF11178.8 RUS81696.1 - 0.018 14.7 0.0 17 5.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2963) Glu_cyclase_2 PF05096.12 RUS81696.1 - 0.068 12.6 0.0 3.3 7.1 0.0 2.7 1 1 2 3 3 3 0 Glutamine cyclotransferase DIM PF08194.12 RUS81699.1 - 0.043 14.0 1.1 0.091 13.0 1.1 1.5 1 0 0 1 1 1 0 DIM protein RT_RNaseH PF17917.1 RUS81700.1 - 1.1e-24 86.7 0.0 2.6e-17 63.0 0.0 2.6 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS81700.1 - 3.5e-22 78.3 0.2 7.1e-21 74.1 0.0 3.0 4 0 0 4 4 4 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS81700.1 - 0.0019 18.4 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS81700.1 - 0.037 13.8 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.6 RUS81701.1 - 0.0034 17.9 0.0 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4722 PF15849.5 RUS81701.1 - 0.085 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) RVT_1 PF00078.27 RUS81702.1 - 0.00064 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fibrinogen_C PF00147.18 RUS81703.1 - 6.4e-18 65.4 1.2 6.5e-18 65.4 0.4 1.4 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF1676 PF07898.13 RUS81703.1 - 0.15 12.1 13.8 0.19 11.8 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) ECH_1 PF00378.20 RUS81704.1 - 4.1e-48 163.9 0.1 7.5e-48 163.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS81704.1 - 5.5e-25 88.6 0.0 2.4e-23 83.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Leo1 PF04004.13 RUS81705.1 - 5.7e-53 179.1 0.0 5.7e-53 179.1 0.0 2.1 2 1 1 3 3 3 1 Leo1-like protein BBS2_Mid PF14783.6 RUS81706.1 - 0.013 15.6 0.0 6.8 6.8 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region GpcrRhopsn4 PF10192.9 RUS81707.1 - 6.5e-48 163.4 20.1 8.8e-48 162.9 20.1 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain p450 PF00067.22 RUS81708.1 - 4.6e-57 193.8 0.0 5.4e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C2 PF00648.21 RUS81709.1 - 1.8e-41 142.1 6.9 4.7e-40 137.5 0.0 2.5 2 1 1 3 3 2 2 Calpain family cysteine protease Calpain_III PF01067.22 RUS81709.1 - 7.2e-10 39.3 6.0 9.5e-07 29.2 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III p450 PF00067.22 RUS81709.1 - 0.002 17.0 9.2 0.029 13.1 0.0 3.1 2 1 0 3 3 2 2 Cytochrome P450 DUF3807 PF12720.7 RUS81709.1 - 0.0024 18.2 17.4 0.0024 18.2 17.4 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF3807) CPSF100_C PF13299.6 RUS81709.1 - 0.0046 17.2 9.0 0.014 15.6 9.0 1.8 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 RUS81709.1 - 0.0064 16.4 15.9 0.0064 16.4 15.9 2.0 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 RUS81709.1 - 0.027 14.6 9.7 0.11 12.5 9.7 2.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein BSMAP PF12280.8 RUS81709.1 - 0.11 12.7 5.2 0.34 11.1 5.2 1.9 1 0 0 1 1 1 0 Brain specific membrane anchored protein Vfa1 PF08432.10 RUS81709.1 - 0.13 12.6 32.3 0.35 11.2 32.3 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 RUS81709.1 - 0.17 12.0 10.5 0.023 14.9 5.1 2.2 2 0 0 2 2 2 0 DDHD domain Tim54 PF11711.8 RUS81709.1 - 0.2 10.4 17.6 0.39 9.5 17.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 RUS81709.1 - 0.32 10.7 18.0 0.66 9.7 18.0 1.4 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 RUS81709.1 - 0.44 9.5 6.1 0.99 8.3 6.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 RUS81709.1 - 0.68 9.3 17.0 1.2 8.5 17.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_11 PF13086.6 RUS81709.1 - 0.7 9.6 17.8 0.017 14.9 9.6 2.0 2 0 0 2 2 2 0 AAA domain LicD PF04991.13 RUS81709.1 - 1 9.5 17.6 2.2 8.4 17.6 1.5 1 0 0 1 1 1 0 LicD family PPL5 PF18168.1 RUS81709.1 - 1.3 8.3 15.2 2.6 7.2 15.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 SRP-alpha_N PF04086.13 RUS81709.1 - 1.5 8.6 35.3 0.02 14.9 20.7 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2828 PF11443.8 RUS81709.1 - 1.6 6.7 21.3 2.6 6.0 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CLN3 PF02487.17 RUS81709.1 - 2.1 7.3 8.5 3.7 6.5 8.5 1.2 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 RUS81709.1 - 2.3 6.9 10.7 4.3 6.0 10.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter EIIBC-GUT_N PF03612.14 RUS81709.1 - 3 7.5 11.8 7.3 6.3 11.8 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3405 PF11885.8 RUS81709.1 - 3.6 6.1 13.6 7 5.1 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) MAP17 PF15807.5 RUS81709.1 - 5.7 7.2 18.1 14 5.9 18.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2052 PF09747.9 RUS81709.1 - 7.4 6.6 16.0 0.13 12.4 8.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Rxt3 PF08642.10 RUS81709.1 - 9.3 7.0 8.7 42 4.9 8.7 2.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF2457 PF10446.9 RUS81710.1 - 0.1 11.7 30.2 0.16 11.1 30.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS81710.1 - 0.14 10.3 15.1 0.18 10.0 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS81710.1 - 0.44 8.6 26.6 0.59 8.2 26.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RUS81710.1 - 0.97 8.7 13.9 1.3 8.3 13.9 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 RUS81710.1 - 1.5 8.5 9.8 3.3 7.4 9.8 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RUS81710.1 - 1.6 6.9 14.5 2.4 6.4 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS81710.1 - 3 7.2 18.1 4 6.8 18.1 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RUS81710.1 - 6 5.3 14.6 8.1 4.9 14.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 RUS81710.1 - 7.5 6.3 10.3 12 5.7 10.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mpp10 PF04006.12 RUS81711.1 - 0.018 13.5 12.4 0.02 13.3 12.4 1.1 1 0 0 1 1 1 0 Mpp10 protein eIF-3c_N PF05470.12 RUS81711.1 - 0.042 12.2 2.8 0.043 12.1 2.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 RUS81711.1 - 0.2 9.7 37.9 0.32 9.1 37.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS81711.1 - 6 4.9 28.1 8 4.5 28.1 1.1 1 0 0 1 1 1 0 Nop14-like family Insulin_TMD PF17870.1 RUS81713.1 - 0.084 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CD34_antigen PF06365.12 RUS81713.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family NVEALA PF14055.6 RUS81713.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 NVEALA protein ETRAMP PF09716.10 RUS81713.1 - 0.15 12.1 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Kunitz_BPTI PF00014.23 RUS81714.1 - 6e-64 212.1 60.4 3.9e-17 62.2 4.9 4.8 4 0 0 4 4 4 4 Kunitz/Bovine pancreatic trypsin inhibitor domain Ig_3 PF13927.6 RUS81714.1 - 1.9e-55 185.4 0.7 2.1e-13 50.6 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 RUS81714.1 - 2.7e-47 158.7 0.0 4.5e-14 52.3 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS81714.1 - 6.2e-42 141.8 0.1 2.5e-10 40.5 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 RUS81714.1 - 6.9e-33 112.7 1.6 4.3e-09 36.4 0.0 6.1 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 RUS81714.1 - 2.2e-18 66.4 4.2 0.0012 19.0 0.1 7.8 6 2 0 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS81714.1 - 3.7e-10 39.7 4.6 0.00094 19.2 0.0 4.9 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS81714.1 - 9.9e-09 35.5 0.0 0.13 12.7 0.0 5.3 5 1 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS81714.1 - 2.2e-08 33.5 0.0 0.027 14.0 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin domain Ig_4 PF16680.5 RUS81714.1 - 7.8e-07 29.3 0.0 0.91 9.8 0.0 5.8 5 1 1 6 6 6 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 RUS81714.1 - 3.9e-06 27.1 0.0 0.019 15.3 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin C1-set domain PLAC PF08686.11 RUS81714.1 - 2e-05 25.2 4.1 2e-05 25.2 4.1 2.8 3 0 0 3 3 1 1 PLAC (protease and lacunin) domain HC2 PF07382.11 RUS81715.1 - 0.002 18.2 26.6 0.0024 18.0 26.6 1.0 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF3332 PF11810.8 RUS81715.1 - 0.46 10.1 6.5 0.58 9.8 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) CfAFP PF05264.11 RUS81715.1 - 0.78 9.7 3.5 1.5 8.8 2.4 1.7 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Plk4_PB2 PF18409.1 RUS81715.1 - 0.86 10.3 9.0 57 4.4 9.0 2.2 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 PBP5_C PF07943.13 RUS81715.1 - 3.9 7.8 7.8 2.3 8.5 2.2 2.1 1 1 1 2 2 2 0 Penicillin-binding protein 5, C-terminal domain VWD PF00094.25 RUS81715.1 - 3.9 7.7 12.0 7.3 6.8 12.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type D domain Gag_MA PF01140.19 RUS81715.1 - 9.7 5.9 14.3 8.9 6.1 0.9 3.2 1 1 2 3 3 3 0 Matrix protein (MA), p15 Kunitz_BPTI PF00014.23 RUS81716.1 - 1.7e-19 69.8 7.4 3.2e-19 68.9 7.4 1.5 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 RUS81717.1 - 4.5e-09 36.4 8.0 4.5e-09 36.4 8.0 3.2 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Gemini_AL2 PF01440.16 RUS81717.1 - 3.2 8.2 10.3 1.6 9.2 0.3 2.9 2 1 1 3 3 3 0 Geminivirus AL2 protein Kunitz_BPTI PF00014.23 RUS81718.1 - 1.4e-31 108.5 30.9 9.5e-17 61.0 8.0 2.7 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 RUS81719.1 - 2.2e-32 111.0 26.0 2e-17 63.1 3.7 3.3 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Colipase_C PF02740.14 RUS81719.1 - 0.81 9.9 24.4 3.2 8.0 0.5 5.7 5 0 0 5 5 5 0 Colipase, C-terminal domain Apt1 PF10351.9 RUS81719.1 - 2.1 7.1 6.3 2.7 6.7 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 RUS81719.1 - 7 5.1 12.2 8.8 4.8 12.2 1.1 1 0 0 1 1 1 0 Macoilin family TSP_1 PF00090.19 RUS81721.1 - 8.1e-09 35.6 56.8 7.7e-05 22.8 10.7 5.8 5 2 0 5 5 5 3 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 RUS81721.1 - 4.9e-08 33.0 0.0 7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 MyTH4 PF00784.17 RUS81722.1 - 1.2e-23 83.7 0.0 2.3e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_N PF09379.10 RUS81722.1 - 0.00013 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain DUF229 PF02995.17 RUS81725.1 - 1e-82 278.4 0.1 1.2e-82 278.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS81725.1 - 0.00011 21.8 0.3 0.003 17.0 0.1 2.1 1 1 1 2 2 2 2 Sulfatase DUF1501 PF07394.12 RUS81725.1 - 0.0041 16.2 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 RUS81725.1 - 0.0073 15.9 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_18 PF13512.6 RUS81725.1 - 0.13 12.3 0.5 0.22 11.6 0.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_22 PF13383.6 RUS81727.1 - 1.8e-25 89.9 0.6 2.4e-25 89.6 0.6 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS81727.1 - 5.7e-06 26.5 0.0 2.6e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase FkbM domain FixQ PF05545.11 RUS81727.1 - 0.035 14.1 2.0 0.89 9.6 1.8 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TssO PF17561.2 RUS81727.1 - 0.04 14.0 0.9 0.047 13.8 0.1 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssO Striatin PF08232.12 RUS81728.1 - 5.9e-51 173.1 0.6 5.9e-51 173.1 0.6 2.6 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 RUS81728.1 - 2.5e-38 129.4 9.4 2.8e-08 34.3 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS81728.1 - 5e-07 29.9 0.1 0.14 12.4 0.0 4.9 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS81728.1 - 0.00043 19.1 0.9 0.62 8.6 0.0 2.9 1 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RUS81728.1 - 0.045 12.5 0.1 33 3.1 0.0 3.5 1 1 4 5 5 5 0 Nup133 N terminal like IalB PF06776.12 RUS81728.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein DUF4482 PF14818.6 RUS81728.1 - 2.8 8.8 11.0 0.093 13.6 1.3 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4482) Clat_adaptor_s PF01217.20 RUS81729.1 - 3.9e-11 43.1 1.2 5.9e-11 42.5 1.2 1.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF4636 PF15468.6 RUS81730.1 - 0.031 14.0 3.7 0.043 13.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Trypan_PARP PF05887.11 RUS81730.1 - 0.15 12.1 4.8 0.34 10.9 4.8 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Kelch_6 PF13964.6 RUS81731.1 - 1.1e-39 133.4 8.9 9.2e-07 28.9 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_1 PF01344.25 RUS81731.1 - 9.3e-34 114.8 7.8 7e-08 31.9 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RUS81731.1 - 5.6e-32 109.5 14.8 2.4e-06 27.4 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS81731.1 - 4e-31 105.8 6.6 1.5e-05 24.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS81731.1 - 5e-31 106.4 12.4 9.4e-06 25.8 0.6 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS81731.1 - 1.9e-28 98.0 11.7 1.8e-05 24.6 0.2 6.4 6 0 0 6 6 6 6 Kelch motif RANK_CRD_2 PF18278.1 RUS81731.1 - 0.034 14.3 0.1 0.085 13.0 0.1 1.7 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 ASH PF15780.5 RUS81734.1 - 4.7e-17 62.0 2.7 9.9e-05 22.5 0.1 7.9 8 1 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RUS81734.1 - 0.00026 21.0 0.0 4.5 7.4 0.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 RUS81734.1 - 0.003 16.6 2.3 0.27 10.1 0.0 3.5 4 0 0 4 4 4 1 MYCBP-associated protein family TMEM131_like PF12371.8 RUS81734.1 - 0.076 13.3 1.4 8.8 6.7 0.0 4.8 7 0 0 7 7 7 0 Transmembrane protein 131-like Transglut_C PF00927.22 RUS81734.1 - 0.16 12.1 0.0 4.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain PAN_3 PF08277.12 RUS81736.1 - 0.0021 17.8 13.5 0.26 11.1 0.7 3.1 1 1 2 3 3 3 3 PAN-like domain LLGL PF08366.13 RUS81736.1 - 0.11 12.8 11.6 8.6 6.8 3.3 3.5 1 1 1 2 2 2 0 LLGL2 tRNA_int_end_N2 PF12928.7 RUS81736.1 - 0.13 12.5 9.0 1.9e+02 2.3 9.0 3.0 1 1 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term SLR1-BP PF07333.12 RUS81736.1 - 0.33 11.4 16.7 18 5.8 0.3 3.9 1 1 2 3 3 3 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Dickkopf_N PF04706.12 RUS81736.1 - 0.35 11.4 15.1 4.3 7.9 2.5 3.3 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF1945 PF09178.10 RUS81736.1 - 0.85 9.9 15.8 0.7 10.1 1.5 4.4 1 1 0 3 3 3 0 Domain of unknown function (DUF1945) PH_2 PF08458.10 RUS81736.1 - 0.96 9.8 12.1 4.3 7.7 3.6 2.3 1 1 1 2 2 2 0 Plant pleckstrin homology-like region UCR_hinge PF02320.16 RUS81736.1 - 1.9 8.7 24.4 5.9e+03 -2.4 24.4 2.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF1687 PF07955.11 RUS81736.1 - 2.2 8.8 5.8 2.5 8.6 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1687) Globin PF00042.22 RUS81737.1 - 2e-05 25.1 0.1 2.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Globin zf-C2H2 PF00096.26 RUS81738.1 - 1.7e-57 188.8 161.8 9.6e-05 22.6 0.9 19.5 19 1 0 19 19 19 17 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81738.1 - 4.1e-57 188.2 125.5 3.6e-09 36.6 0.8 18.9 19 0 0 19 19 19 14 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS81738.1 - 1e-52 172.2 156.2 0.00028 21.5 0.8 19.2 19 0 0 19 19 19 18 C2H2-type zinc finger zf-met PF12874.7 RUS81738.1 - 2.1e-10 40.6 112.0 0.0026 18.1 1.2 17.4 18 0 0 18 18 18 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS81738.1 - 3.5e-10 39.9 90.9 0.00076 19.7 2.6 16.7 16 3 2 18 18 18 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS81738.1 - 2.2e-05 24.3 125.0 0.028 14.4 3.4 18.1 19 1 1 20 20 20 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS81738.1 - 5.4e-05 22.9 0.2 5.4e-05 22.9 0.2 16.5 17 3 0 17 17 15 7 C2H2-type zinc-finger domain zf-met2 PF12907.7 RUS81738.1 - 0.00044 20.3 1.1 0.00044 20.3 1.1 6.7 9 1 0 9 9 9 2 Zinc-binding zinc_ribbon_15 PF17032.5 RUS81738.1 - 0.0017 19.1 71.2 0.31 11.8 1.9 10.1 2 2 7 11 11 11 7 zinc-ribbon family zf-C2H2_11 PF16622.5 RUS81738.1 - 0.034 13.9 0.7 0.034 13.9 0.7 16.4 16 1 1 17 17 17 0 zinc-finger C2H2-type DUF3268 PF11672.8 RUS81738.1 - 0.27 11.6 43.4 0.53 10.6 0.5 7.7 5 2 4 9 9 9 0 zinc-finger-containing domain zf-C2H2 PF00096.26 RUS81739.1 - 6.2e-20 70.5 38.2 4.3e-06 26.9 2.1 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS81739.1 - 2.9e-16 58.7 39.7 0.0022 18.7 1.6 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS81739.1 - 1.9e-08 34.4 39.7 0.00033 21.0 0.4 6.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-met PF12874.7 RUS81739.1 - 2.4e-05 24.6 24.5 1.5 9.3 0.9 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS81739.1 - 0.014 15.4 0.6 0.014 15.4 0.6 6.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-Di19 PF05605.12 RUS81739.1 - 0.14 12.5 26.8 0.29 11.4 0.1 4.6 2 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 RUS81739.1 - 0.24 11.8 26.2 12 6.3 7.0 4.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RUS81739.1 - 1.6 9.1 22.8 0.44 10.9 0.7 5.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 RUS81739.1 - 4 7.5 19.4 7 6.7 0.1 5.4 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_7 PF15269.6 RUS81739.1 - 4.4 7.5 13.1 1.9 8.6 0.3 3.7 2 2 1 3 3 3 0 Zinc-finger DUF3268 PF11672.8 RUS81739.1 - 4.6 7.6 11.8 5.1 7.5 1.4 3.1 2 1 1 3 3 3 0 zinc-finger-containing domain zf-C2H2_4 PF13894.6 RUS81740.1 - 3e-27 92.9 90.7 0.0025 18.5 1.1 12.8 12 0 0 12 12 12 9 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS81740.1 - 1.2e-25 88.4 101.5 5.4e-06 26.6 2.1 13.1 12 1 0 12 12 12 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81740.1 - 3.2e-12 46.3 92.3 0.0019 18.6 0.3 12.8 13 0 0 13 13 13 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS81740.1 - 0.0012 18.8 7.9 0.0088 16.0 1.5 10.7 12 0 0 12 12 11 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS81740.1 - 0.011 15.5 4.7 0.011 15.5 4.7 10.2 10 0 0 10 10 9 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS81740.1 - 0.023 14.5 0.2 0.023 14.5 0.2 8.9 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-met PF12874.7 RUS81740.1 - 0.1 13.0 0.2 0.1 13.0 0.2 9.7 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 RUS81740.1 - 0.13 12.2 0.1 0.13 12.2 0.1 7.2 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RUS81740.1 - 0.54 10.6 51.4 0.25 11.7 1.5 9.9 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding DUF899 PF05988.12 RUS81740.1 - 0.59 9.6 6.3 4.3 6.8 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF899) FdhD-NarQ PF02634.15 RUS81740.1 - 0.61 9.7 3.0 0.41 10.3 0.4 2.0 2 1 0 2 2 2 0 FdhD/NarQ family Cript PF10235.9 RUS81742.1 - 3.7e-37 126.8 5.5 3.7e-37 126.8 5.5 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 RUS81742.1 - 0.016 15.5 15.9 0.16 12.3 15.9 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 RUS81742.1 - 0.076 13.4 7.5 0.21 12.0 3.3 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal Gin PF10764.9 RUS81742.1 - 0.16 12.0 7.1 5.6 7.0 0.1 2.8 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF1272 PF06906.11 RUS81742.1 - 0.32 11.1 7.0 0.7 10.0 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.6 RUS81742.1 - 0.83 9.5 13.0 7.7 6.4 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 RUS81742.1 - 1.3 9.1 9.2 0.62 10.1 4.9 2.0 2 0 0 2 2 2 0 Transposase zinc-binding domain zinc_ribbon_15 PF17032.5 RUS81742.1 - 1.4 9.7 12.8 7.8 7.3 8.4 2.7 2 1 0 2 2 2 0 zinc-ribbon family PLATZ PF04640.14 RUS81742.1 - 2.4 8.8 9.6 1.2 9.8 1.6 2.9 2 1 1 3 3 3 0 PLATZ transcription factor Peptidase_C13 PF01650.18 RUS81743.1 - 3.5e-102 341.3 0.0 5.1e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Gln-synt_C-ter PF18318.1 RUS81743.1 - 0.11 12.4 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain Thioredoxin PF00085.20 RUS81747.1 - 4.3e-08 33.1 0.0 5.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RUS81747.1 - 0.065 13.7 0.1 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 RUS81748.1 - 7.4e-11 42.0 0.3 9.1e-11 41.7 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 RUS81748.1 - 0.0045 16.9 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 RUS81748.1 - 0.015 15.7 0.3 0.023 15.1 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS81748.1 - 0.11 12.8 0.1 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Vasohibin PF14822.6 RUS81749.1 - 2e-72 243.4 0.2 4e-53 180.2 0.0 2.1 1 1 1 2 2 2 2 Vasohibin Asp5 PF17000.5 RUS81749.1 - 0.49 10.6 3.6 1.1 9.5 3.6 1.6 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 TMEM247 PF15444.6 RUS81749.1 - 2.9 7.9 4.1 0.66 10.0 0.9 1.5 2 0 0 2 2 2 0 Transmembrane protein 247 Erg28 PF03694.13 RUS81750.1 - 1.1e-31 109.4 3.3 1.4e-31 109.1 3.3 1.1 1 0 0 1 1 1 1 Erg28 like protein p53-inducible11 PF14936.6 RUS81750.1 - 0.0094 16.0 6.1 0.012 15.7 6.1 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF308 PF03729.13 RUS81750.1 - 0.049 14.0 1.1 0.049 14.0 1.1 2.6 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Cyt_c_ox_IV PF12270.8 RUS81750.1 - 0.087 13.0 0.3 0.087 13.0 0.3 2.5 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV DUF4267 PF14087.6 RUS81750.1 - 0.32 11.1 2.5 0.44 10.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) DUF4345 PF14248.6 RUS81750.1 - 1.9 8.4 9.3 0.083 12.8 4.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) CH PF00307.31 RUS81751.1 - 3.2e-09 36.9 0.0 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain HTH_49 PF18010.1 RUS81751.1 - 0.035 14.0 0.2 1.7e+02 2.2 0.0 5.1 3 0 0 3 3 3 0 Cry35Ab1 HTH C-terminal domain CH PF00307.31 RUS81752.1 - 2.6e-32 111.3 0.0 2e-22 79.5 0.0 3.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Spectrin PF00435.21 RUS81752.1 - 2.8e-08 34.2 68.2 0.0035 17.8 1.3 9.0 7 1 2 9 9 8 5 Spectrin repeat CAMSAP_CH PF11971.8 RUS81752.1 - 5.5e-05 22.9 0.0 0.00022 21.0 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain Laminin_II PF06009.12 RUS81752.1 - 0.013 15.5 14.0 0.23 11.5 0.2 5.5 4 2 1 5 5 5 0 Laminin Domain II Bacillus_HBL PF05791.11 RUS81752.1 - 0.034 14.0 12.8 0.19 11.6 3.4 4.9 3 1 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) PMBR PF09373.10 RUS81752.1 - 0.12 12.6 0.0 0.46 10.7 0.0 2.0 1 0 0 1 1 1 0 Pseudomurein-binding repeat PEP-utilisers_N PF05524.13 RUS81752.1 - 0.22 11.7 3.8 2 8.6 0.8 3.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal FUSC PF04632.12 RUS81752.1 - 1.2 7.6 16.5 0.083 11.4 3.5 3.5 2 1 0 4 4 4 0 Fusaric acid resistance protein family DUF948 PF06103.11 RUS81752.1 - 4.2 7.7 8.0 14 6.0 1.6 4.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3496 PF12001.8 RUS81752.1 - 6.2 7.2 9.3 1.9 8.9 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) MitMem_reg PF13012.6 RUS81752.1 - 8.7 6.8 7.6 76 3.8 2.5 5.0 2 2 1 3 3 3 0 Maintenance of mitochondrial structure and function Spectrin PF00435.21 RUS81753.1 - 3.6e-22 78.8 35.8 1.6e-10 41.4 3.2 4.3 4 0 0 4 4 4 4 Spectrin repeat Fic PF02661.18 RUS81753.1 - 0.0064 17.4 4.7 0.83 10.6 0.0 3.9 2 1 2 4 4 4 1 Fic/DOC family Syntaxin-6_N PF09177.11 RUS81753.1 - 0.0096 16.5 0.6 0.0096 16.5 0.6 4.5 2 2 2 4 4 4 1 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 RUS81753.1 - 0.027 14.5 9.7 0.043 13.9 0.1 3.7 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 RUS81753.1 - 0.34 11.2 5.7 8.1 6.8 0.4 4.1 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4107 PF13389.6 RUS81753.1 - 0.58 10.3 5.0 0.87 9.7 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4107) CorA PF01544.18 RUS81753.1 - 0.92 8.8 6.8 0.46 9.8 1.5 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 RUS81753.1 - 1.1 9.4 11.6 5.7 7.0 0.1 4.3 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 RUS81753.1 - 8.5 5.7 15.6 3.2 7.1 1.6 3.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Spectrin PF00435.21 RUS81754.1 - 1.7e-58 195.6 109.4 4e-09 36.9 5.0 12.6 11 1 2 13 13 13 10 Spectrin repeat Spc7 PF08317.11 RUS81754.1 - 0.0012 17.8 13.2 0.0042 16.0 6.9 10.6 1 1 8 11 11 11 8 Spc7 kinetochore protein Filament PF00038.21 RUS81754.1 - 0.0037 16.9 0.8 0.0037 16.9 0.8 7.2 3 1 3 7 7 7 3 Intermediate filament protein Cas_DxTHG PF09455.10 RUS81754.1 - 0.017 14.8 20.2 0.05 13.2 3.6 4.4 1 1 0 3 3 3 0 CRISPR-associated (Cas) DxTHG family TcdB_N PF12918.7 RUS81754.1 - 0.082 13.2 2.5 9.5 6.6 0.1 4.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain DUF1977 PF09320.11 RUS81754.1 - 0.39 11.0 0.1 0.39 11.0 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) Spectrin PF00435.21 RUS81755.1 - 5.3e-55 184.4 106.5 1.6e-09 38.2 2.7 11.8 11 1 1 12 12 12 10 Spectrin repeat ATP-synt_D PF01813.17 RUS81755.1 - 0.18 11.6 34.3 0.28 11.0 1.7 6.9 7 1 0 7 7 7 0 ATP synthase subunit D DinB_2 PF12867.7 RUS81755.1 - 3.7 8.1 10.3 1.5 9.3 0.2 4.8 4 1 0 4 4 4 0 DinB superfamily Spectrin PF00435.21 RUS81756.1 - 7.9e-38 129.2 89.4 9.9e-07 29.2 3.3 11.4 10 1 1 11 11 11 9 Spectrin repeat RNase_3_N PF18497.1 RUS81756.1 - 0.13 12.5 2.2 13 6.0 0.0 4.2 4 0 0 4 4 4 0 Ribonuclease III N-terminal domain DUF2721 PF11026.8 RUS81756.1 - 1.3 8.9 4.4 8.2 6.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Kindlin_2_N PF18124.1 RUS81756.1 - 6.3 7.1 14.8 2.9 8.1 0.5 4.6 4 0 0 4 4 4 0 Kindlin-2 N-terminal domain Mating_N PF12731.7 RUS81756.1 - 8.5 6.5 27.2 1.2 9.3 0.4 6.9 8 0 0 8 8 8 0 Mating-type protein beta 1 zf-C2H2 PF00096.26 RUS81758.1 - 9.2e-16 57.3 29.8 7.7e-05 22.9 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS81758.1 - 7.7e-13 48.1 25.7 0.00092 19.9 0.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS81758.1 - 4.7e-12 45.8 29.1 8.3e-09 35.5 2.3 5.1 5 1 0 5 5 4 3 Zinc-finger double domain FYVE PF01363.21 RUS81758.1 - 1.1e-06 28.7 14.2 0.0044 17.1 2.3 2.4 1 1 1 2 2 2 2 FYVE zinc finger zf-C2H2_3rep PF18868.1 RUS81758.1 - 3e-06 27.9 13.5 0.0025 18.5 3.1 2.8 1 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 RUS81758.1 - 0.00033 20.7 11.2 0.65 10.2 0.8 4.2 4 0 0 4 4 4 2 Zinc ribbon domain Cript PF10235.9 RUS81758.1 - 0.0026 18.3 0.4 0.0026 18.3 0.4 3.1 2 1 1 3 3 3 1 Microtubule-associated protein CRIPT zf-met PF12874.7 RUS81758.1 - 0.0031 17.8 13.1 0.78 10.2 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type XPA_N PF01286.18 RUS81758.1 - 0.0074 16.3 9.2 6.9 6.8 0.1 4.2 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 RUS81758.1 - 0.01 16.1 17.1 0.3 11.4 0.6 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS81758.1 - 0.014 15.1 20.7 0.023 14.4 3.0 3.8 4 0 0 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RUS81758.1 - 0.023 15.5 9.9 0.54 11.0 1.5 2.7 1 1 3 4 4 4 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 RUS81758.1 - 0.026 14.8 2.8 2.5 8.4 0.2 3.6 3 1 0 3 3 3 0 zinc-ribbon DUF629 PF04780.12 RUS81758.1 - 0.029 12.9 11.0 0.061 11.9 1.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 RUS81758.1 - 0.058 13.0 10.8 4.4 7.0 1.3 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger FdhD-NarQ PF02634.15 RUS81758.1 - 0.071 12.8 0.6 0.11 12.1 0.6 1.3 1 0 0 1 1 1 0 FdhD/NarQ family UNC-79 PF14776.6 RUS81758.1 - 0.074 11.8 0.5 0.098 11.4 0.5 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 FpoO PF10621.9 RUS81758.1 - 0.11 12.8 5.5 0.54 10.6 2.2 2.5 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-C2HC_2 PF13913.6 RUS81758.1 - 0.21 11.6 12.1 2.7 8.0 0.2 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 RUS81758.1 - 0.28 11.3 5.5 9.6 6.4 0.4 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Rubredoxin_2 PF18073.1 RUS81758.1 - 0.33 10.7 9.8 1.7 8.5 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-C2H2_6 PF13912.6 RUS81758.1 - 0.41 10.7 24.1 0.54 10.3 0.9 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 RUS81758.1 - 0.45 10.2 8.1 9.6 5.9 0.0 3.8 3 1 1 4 4 4 0 MYST family zinc finger domain C1_1 PF00130.22 RUS81758.1 - 0.53 10.2 9.8 0.086 12.7 2.2 3.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.12 RUS81758.1 - 0.75 9.5 13.2 1.4 8.6 0.3 3.9 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain DUF2197 PF09963.9 RUS81758.1 - 0.83 10.0 16.3 0.19 12.0 4.4 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) ADK_lid PF05191.14 RUS81758.1 - 0.93 9.5 10.7 0.88 9.6 4.5 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid YhfH PF14149.6 RUS81758.1 - 1.3 9.1 5.4 6 6.9 0.4 3.2 3 0 0 3 3 3 0 YhfH-like protein PyrI_C PF02748.15 RUS81758.1 - 1.6 8.7 9.6 7.2 6.6 0.4 3.8 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 RUS81758.1 - 2.4 8.1 18.9 3 7.8 1.0 3.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-Di19 PF05605.12 RUS81758.1 - 2.4 8.5 16.6 0.42 10.9 0.8 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zf_RING PF16744.5 RUS81758.1 - 3.7 7.7 12.9 10 6.3 0.2 3.3 1 1 2 3 3 3 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 RUS81758.1 - 4.4 7.3 11.7 16 5.5 0.1 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Lig_chan PF00060.26 RUS81760.1 - 6.9e-50 168.8 0.3 9e-50 168.4 0.3 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS81760.1 - 3.7e-28 98.0 0.0 7.1e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS81760.1 - 2e-19 69.9 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 RUS81760.1 - 1.2e-12 47.6 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SfLAP PF11139.8 RUS81760.1 - 0.016 14.6 0.3 0.12 11.8 0.1 2.2 2 1 0 2 2 2 0 Sap, sulfolipid-1-addressing protein ANF_receptor PF01094.28 RUS81761.1 - 5.8e-11 42.1 0.0 9.7e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region CPSF100_C PF13299.6 RUS81761.1 - 0.0012 19.1 2.5 0.0017 18.5 2.5 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Ureide_permease PF07168.11 RUS81761.1 - 0.0046 15.8 0.8 0.0063 15.3 0.8 1.1 1 0 0 1 1 1 1 Ureide permease FAM176 PF14851.6 RUS81761.1 - 0.0095 15.6 5.0 0.016 14.9 5.0 1.3 1 0 0 1 1 1 1 FAM176 family Tim54 PF11711.8 RUS81761.1 - 0.015 14.1 8.4 0.02 13.7 8.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AP3D1 PF06375.11 RUS81761.1 - 0.017 15.4 14.9 0.024 14.9 14.9 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 AFT PF08731.11 RUS81761.1 - 0.019 15.4 5.3 0.027 14.8 5.3 1.2 1 0 0 1 1 1 0 Transcription factor AFT DUF2370 PF10176.9 RUS81761.1 - 0.025 14.2 0.3 0.038 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RR_TM4-6 PF06459.12 RUS81761.1 - 0.028 14.2 10.9 0.039 13.8 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 RUS81761.1 - 0.03 14.8 5.6 0.046 14.2 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 RUS81761.1 - 0.038 14.3 5.9 0.055 13.8 5.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Zip PF02535.22 RUS81761.1 - 0.06 12.6 0.6 0.065 12.5 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 RUS81761.1 - 0.06 12.1 5.4 0.077 11.8 5.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SpoIIP PF07454.11 RUS81761.1 - 0.062 12.7 9.8 0.086 12.3 9.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 RUS81761.1 - 0.068 12.1 0.9 0.087 11.8 0.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 RUS81761.1 - 0.072 12.8 6.1 0.11 12.2 6.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TFIIF_alpha PF05793.12 RUS81761.1 - 0.076 11.6 17.7 0.097 11.2 17.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RPN2_C PF18004.1 RUS81761.1 - 0.084 12.8 18.3 0.12 12.3 18.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Connexin PF00029.19 RUS81761.1 - 0.1 12.4 8.8 0.14 11.9 8.8 1.1 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 RUS81761.1 - 0.13 12.6 17.8 0.18 12.2 17.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 RUS81761.1 - 0.14 11.6 7.8 0.22 10.9 7.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FHIPEP PF00771.20 RUS81761.1 - 0.16 10.4 4.1 0.22 10.0 4.1 1.1 1 0 0 1 1 1 0 FHIPEP family Neur_chan_memb PF02932.16 RUS81761.1 - 0.18 11.8 2.8 0.27 11.2 2.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PSK PF06404.12 RUS81761.1 - 0.2 12.7 12.2 0.088 13.8 9.2 1.8 2 0 0 2 2 1 0 Phytosulfokine precursor protein (PSK) CENP-N PF05238.13 RUS81761.1 - 0.2 10.9 6.3 0.26 10.5 6.3 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like AAA_23 PF13476.6 RUS81761.1 - 0.21 12.1 14.8 0.3 11.6 14.8 1.2 1 0 0 1 1 1 0 AAA domain EOS1 PF12326.8 RUS81761.1 - 0.24 11.3 1.5 0.35 10.8 1.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF262 PF03235.14 RUS81761.1 - 0.27 11.4 4.3 0.36 11.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Presenilin PF01080.17 RUS81761.1 - 0.28 9.9 4.6 0.35 9.6 4.6 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_U57 PF05582.12 RUS81761.1 - 0.31 10.3 4.6 0.41 9.9 4.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3391 PF11871.8 RUS81761.1 - 0.33 11.5 9.1 0.51 10.9 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Nucleoside_tran PF01733.18 RUS81761.1 - 0.38 10.1 1.0 0.52 9.6 1.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF4820 PF16091.5 RUS81761.1 - 0.38 10.1 5.5 0.55 9.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 RUS81761.1 - 0.4 9.9 5.9 0.55 9.4 5.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit U79_P34 PF03064.16 RUS81761.1 - 0.44 9.9 14.5 0.59 9.5 14.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Trypan_PARP PF05887.11 RUS81761.1 - 0.68 9.9 9.1 1.1 9.2 9.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MMM1 PF10296.9 RUS81761.1 - 0.68 8.9 3.8 1.1 8.3 3.8 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 RAB3GAP2_C PF14656.6 RUS81761.1 - 0.75 8.0 6.4 1.1 7.3 6.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus V_ATPase_I PF01496.19 RUS81761.1 - 0.88 7.4 6.1 1.1 7.0 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.13 RUS81761.1 - 0.88 8.4 7.9 1.2 8.0 7.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NARP1 PF12569.8 RUS81761.1 - 0.95 8.3 16.5 1.3 7.9 16.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPA43_OB PF17875.1 RUS81761.1 - 0.97 10.1 6.8 1.6 9.4 6.8 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Protocadherin PF08374.11 RUS81761.1 - 1 9.3 4.8 1.4 8.8 4.8 1.1 1 0 0 1 1 1 0 Protocadherin OATP PF03137.20 RUS81761.1 - 1 7.5 2.0 1.2 7.3 2.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Eapp_C PF10238.9 RUS81761.1 - 1.1 9.4 9.6 1.5 8.9 9.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Serinc PF03348.15 RUS81761.1 - 1.1 8.0 2.6 1.4 7.7 2.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.18 RUS81761.1 - 1.2 7.8 4.2 1.6 7.4 4.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier AF-4 PF05110.13 RUS81761.1 - 1.2 7.1 14.1 1.5 6.8 14.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TERB2 PF15101.6 RUS81761.1 - 1.3 9.0 5.1 1.8 8.6 5.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AAA_11 PF13086.6 RUS81761.1 - 1.4 8.6 8.8 2 8.1 8.8 1.2 1 0 0 1 1 1 0 AAA domain EMC3_TMCO1 PF01956.16 RUS81761.1 - 1.6 8.4 3.9 2.1 8.0 3.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2828 PF11443.8 RUS81761.1 - 1.6 6.7 12.5 2.3 6.2 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CLN3 PF02487.17 RUS81761.1 - 1.8 7.6 4.6 2.3 7.2 4.6 1.1 1 0 0 1 1 1 0 CLN3 protein EIIBC-GUT_N PF03612.14 RUS81761.1 - 2.1 8.0 10.4 3.3 7.4 10.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4637 PF15470.6 RUS81761.1 - 2.3 7.9 14.5 3.3 7.4 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PPL5 PF18168.1 RUS81761.1 - 2.4 7.4 8.6 3.2 7.0 8.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DNApol_Exo PF18136.1 RUS81761.1 - 2.8 7.0 7.3 4 6.5 7.3 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CDC45 PF02724.14 RUS81761.1 - 2.9 6.1 13.0 3.8 5.7 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4770 PF15994.5 RUS81761.1 - 3.5 7.8 10.1 5.2 7.3 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MAP17 PF15807.5 RUS81761.1 - 3.5 7.9 12.5 5.2 7.3 12.5 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Membralin PF09746.9 RUS81761.1 - 3.8 6.5 4.3 4.9 6.1 4.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein DDRGK PF09756.9 RUS81761.1 - 3.9 7.0 29.7 5.6 6.5 29.7 1.1 1 0 0 1 1 1 0 DDRGK domain GNAT_acetyltr_2 PF13718.6 RUS81761.1 - 4.2 6.7 6.0 6.2 6.2 6.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 HNOBA PF07701.14 RUS81761.1 - 4.7 6.6 7.5 7.4 5.9 7.5 1.2 1 0 0 1 1 1 0 Heme NO binding associated ALMT PF11744.8 RUS81761.1 - 5.2 5.8 7.3 6.8 5.4 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AIF_C PF14721.6 RUS81761.1 - 5.7 7.3 8.6 8.9 6.7 8.6 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Conotoxin PF02950.17 RUS81761.1 - 7.1 7.7 9.1 56 4.8 9.1 2.0 1 1 0 1 1 1 0 Conotoxin Peptidase_S49_N PF08496.10 RUS81761.1 - 7.9 6.5 14.9 13 5.8 14.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HORMA PF02301.18 RUS81762.1 - 5.7e-20 71.8 0.5 9.8e-20 71.1 0.5 1.3 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 RUS81762.1 - 0.0014 18.5 0.7 0.0033 17.3 0.7 1.7 1 1 1 2 2 2 1 Bacterial HORMA domain 2 ATG101 PF07855.12 RUS81762.1 - 0.0036 17.3 0.8 0.077 13.0 0.8 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 FAIM1 PF06905.13 RUS81762.1 - 0.01 15.5 1.8 0.018 14.8 1.8 1.4 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Csm1_B PF18211.1 RUS81762.1 - 0.15 11.9 0.1 0.41 10.5 0.1 1.7 1 0 0 1 1 1 0 Csm1 subunit domain B BTB PF00651.31 RUS81763.1 - 6.2e-20 71.5 0.2 3.8e-15 56.1 0.0 3.9 3 1 1 4 4 4 2 BTB/POZ domain HBS1_N PF08938.10 RUS81763.1 - 0.0011 19.2 0.0 0.0038 17.5 0.0 2.0 1 0 0 1 1 1 1 HBS1 N-terminus DUF3719 PF12516.8 RUS81765.1 - 1e-14 53.9 0.2 3e-11 42.9 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3719) SUIM_assoc PF16619.5 RUS81767.1 - 0.025 14.6 1.8 0.025 14.6 1.8 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DASH_Hsk3 PF08227.11 RUS81768.1 - 0.021 15.2 11.1 5.4 7.5 0.7 4.7 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like QVR PF17064.5 RUS81769.1 - 0.0015 18.7 8.1 0.0024 18.1 8.1 1.3 1 1 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 RUS81769.1 - 1.3 9.1 11.4 2.4 8.1 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF753) RNase_P_Rpp14 PF01900.19 RUS81770.1 - 2.5e-05 24.5 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Ig_2 PF13895.6 RUS81771.1 - 7.9e-17 61.4 7.2 0.00019 21.7 0.0 5.0 4 1 1 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.6 RUS81771.1 - 2.6e-13 50.3 2.7 0.00024 21.7 0.0 4.6 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 RUS81771.1 - 1.8e-07 31.2 6.2 0.34 11.1 0.0 5.4 4 2 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 RUS81771.1 - 1.4e-06 28.6 1.9 0.11 13.0 0.1 4.3 4 1 1 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain I-set PF07679.16 RUS81771.1 - 9e-06 25.7 2.9 4.8 7.3 0.1 4.8 4 1 0 4 4 4 3 Immunoglobulin I-set domain V-set PF07686.17 RUS81771.1 - 1.5e-05 25.1 6.2 3.5 7.8 0.1 5.4 4 2 1 6 6 6 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS81771.1 - 0.00022 21.2 0.5 4.8 7.3 0.0 4.5 4 1 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS81771.1 - 0.00023 21.4 4.2 1.5 9.1 0.1 4.4 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Membrane_bind PF14564.6 RUS81771.1 - 0.021 15.3 0.6 0.39 11.2 0.1 2.9 4 0 0 4 4 4 0 Membrane binding Galactosyl_T PF01762.21 RUS81772.1 - 2.4e-36 125.4 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 RUS81773.1 - 6e-19 68.6 0.0 1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase OAD_gamma PF04277.13 RUS81773.1 - 0.065 13.8 0.1 0.16 12.6 0.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain adh_short PF00106.25 RUS81774.1 - 2.4e-18 66.3 0.7 4.7e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS81774.1 - 8.1e-08 32.1 0.9 0.0067 16.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 RUS81775.1 - 2.1e-14 53.9 0.3 4.8e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS81775.1 - 1e-13 51.5 0.2 4.3e-05 24.0 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS81775.1 - 3.9e-13 48.3 0.2 0.00055 20.2 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS81775.1 - 3e-12 46.5 0.0 3.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS81775.1 - 1.6e-11 44.1 5.6 4.4e-06 26.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat CALM_bind PF16025.5 RUS81776.1 - 4.4e-14 52.7 0.2 4.4e-14 52.7 0.2 3.1 3 0 0 3 3 3 1 Calcium-dependent calmodulin binding 3HCDH_N PF02737.18 RUS81776.1 - 1.5 8.6 3.7 0.86 9.5 0.6 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Exo_endo_phos_2 PF14529.6 RUS81778.1 - 7.5e-10 38.7 0.7 7.5e-10 38.7 0.7 2.4 2 1 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 RUS81778.1 - 3.8e-07 30.4 0.9 3.8e-07 30.4 0.9 2.2 2 1 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 RUS81778.1 - 9.9e-06 25.2 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4864 PF16156.5 RUS81778.1 - 0.066 13.9 0.6 0.15 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4864) 7tm_1 PF00001.21 RUS81779.1 - 1.2e-52 178.9 9.8 1.5e-52 178.5 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS81779.1 - 1.9e-09 37.6 16.3 3.1e-09 36.9 16.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS81779.1 - 9.4e-08 31.7 8.7 1.3e-07 31.3 8.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS81779.1 - 9.7e-07 28.8 7.7 1.1e-05 25.3 7.7 2.2 1 1 0 1 1 1 1 Olfactory receptor Exo_endo_phos_2 PF14529.6 RUS81781.1 - 6.4e-22 77.6 1.8 4.6e-21 74.9 0.2 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS81781.1 - 1.7e-10 40.9 0.1 1.1e-09 38.2 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MutS_IV PF05190.18 RUS81781.1 - 0.057 13.8 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 MutS family domain IV HLH PF00010.26 RUS81781.1 - 0.094 12.7 0.5 0.24 11.4 0.5 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain SLATT_4 PF18186.1 RUS81782.1 - 0.018 14.7 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Prefoldin_3 PF13758.6 RUS81782.1 - 0.061 13.4 1.2 0.077 13.1 1.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit IL31 PF15209.6 RUS81782.1 - 0.071 12.9 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Interleukin 31 7tm_1 PF00001.21 RUS81783.1 - 1.2e-34 119.8 5.6 1.7e-34 119.4 5.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS81783.1 - 0.0037 16.7 2.9 0.17 11.2 0.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS81783.1 - 0.0041 16.8 8.5 0.0057 16.3 0.2 2.4 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS81783.1 - 0.0051 16.6 4.0 0.089 12.5 4.0 2.3 1 1 0 1 1 1 1 Olfactory receptor Fig1 PF12351.8 RUS81783.1 - 0.11 12.3 1.6 0.16 11.9 0.3 1.8 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF485 PF04341.12 RUS81783.1 - 0.28 11.2 3.4 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF2852 PF11014.8 RUS81783.1 - 0.7 10.1 0.1 0.7 10.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) CBM_2 PF00553.19 RUS81784.1 - 0.01 16.1 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Cellulose binding domain DUF3995 PF13160.6 RUS81785.1 - 0.022 15.1 5.5 0.44 10.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) RNase_H PF00075.24 RUS81786.1 - 2.4e-14 53.7 0.2 2.4e-14 53.7 0.2 2.7 3 1 0 3 3 3 1 RNase H RVT_3 PF13456.6 RUS81786.1 - 0.00013 21.8 0.0 0.00054 19.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like RVT_1 PF00078.27 RUS81787.1 - 1.1e-43 149.4 0.2 2.1e-43 148.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 RUS81787.1 - 0.068 11.9 23.2 0.097 11.4 23.2 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 RUS81787.1 - 2 7.0 13.3 2.5 6.7 13.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 RUS81787.1 - 6 5.0 35.7 9.7 4.3 35.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 RUS81788.1 - 0.031 14.3 27.9 0.048 13.7 27.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_5 PF13873.6 RUS81788.1 - 1.2 9.3 3.8 6.7 6.9 0.7 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Exonuc_VII_L PF02601.15 RUS81788.1 - 8.7 5.8 14.8 13 5.3 14.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MRP-S34 PF16053.5 RUS81789.1 - 2e-32 111.5 0.1 2.6e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 RSRP PF17069.5 RUS81789.1 - 0.12 11.9 0.5 0.17 11.4 0.5 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF1659 PF07872.11 RUS81789.1 - 0.16 11.6 0.4 2.4 7.9 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1659) Exo_endo_phos_2 PF14529.6 RUS81790.1 - 1e-17 64.1 0.3 1e-17 64.1 0.3 3.1 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 RUS81790.1 - 1.2e-13 51.4 1.0 3.1e-13 50.1 0.0 2.3 2 1 1 3 3 3 1 RNase H zf-RVT PF13966.6 RUS81790.1 - 4.5e-07 30.5 0.4 2.2e-06 28.3 0.4 2.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 RUS81790.1 - 0.017 14.7 0.2 0.037 13.6 0.2 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family AMP_N PF05195.16 RUS81790.1 - 0.026 14.2 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain YdjO PF14169.6 RUS81790.1 - 0.071 12.9 1.1 1 9.1 0.1 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO MBR1 PF17058.5 RUS81790.1 - 4.6 7.5 10.7 1 9.6 6.4 2.0 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 PAS_3 PF08447.12 RUS81791.1 - 4.9e-24 84.4 0.2 1.4e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 RUS81791.1 - 5.8e-18 65.1 0.6 2.7e-16 59.7 0.2 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 RUS81791.1 - 1.4e-13 50.9 0.0 6e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 RUS81791.1 - 2e-06 27.7 0.2 4.1e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 RUS81791.1 - 2.2e-06 27.9 0.0 0.0016 18.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain RVT_1 PF00078.27 RUS81792.1 - 3.3e-45 154.3 0.0 6.9e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS81792.1 - 2.2e-15 56.5 0.3 1.1e-14 54.3 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Rad9 PF04139.13 RUS81792.1 - 0.04 13.4 0.1 0.096 12.1 0.1 1.6 1 0 0 1 1 1 0 Rad9 TetR_C_3 PF08362.11 RUS81792.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region HEAT_PBS PF03130.16 RUS81792.1 - 0.14 12.9 0.1 52 4.9 0.0 2.8 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat PHD PF00628.29 RUS81793.1 - 1.7e-05 24.6 12.4 3.7e-05 23.5 12.4 1.6 1 0 0 1 1 1 1 PHD-finger GatB_Yqey PF02637.18 RUS81793.1 - 0.00068 19.5 5.8 0.0011 18.8 5.8 1.2 1 0 0 1 1 1 1 GatB domain C1_1 PF00130.22 RUS81793.1 - 0.0075 16.1 2.6 0.0075 16.1 2.6 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 RUS81793.1 - 0.092 13.0 5.5 0.31 11.3 5.5 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hexokinase_2 PF03727.16 RUS81795.1 - 1.2e-67 227.9 0.0 1.5e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RUS81795.1 - 6.4e-44 150.2 0.0 1.1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase LIM PF00412.22 RUS81796.1 - 6.5e-58 192.8 97.4 7e-12 45.4 7.5 7.3 7 0 0 7 7 7 6 LIM domain PET PF06297.14 RUS81796.1 - 2e-24 85.7 0.1 4.1e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 PET Domain HA2 PF04408.23 RUS81797.1 - 5.1e-21 75.0 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS81797.1 - 1.1e-20 73.8 0.1 2.6e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS81797.1 - 7.8e-16 58.4 0.2 5.8e-15 55.6 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS81797.1 - 4.2e-07 29.9 0.2 7.7e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS81797.1 - 0.00052 20.3 0.1 0.0019 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 RUS81797.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 RUS81797.1 - 0.017 15.4 0.2 0.045 14.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RUS81797.1 - 0.026 14.2 0.1 0.058 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M48_N PF16491.5 RUS81798.1 - 9.3e-69 231.0 4.4 9.3e-69 231.0 4.4 2.3 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 RUS81798.1 - 2.9e-53 180.6 0.3 4.8e-53 179.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M48 Sec62 PF03839.16 RUS81798.1 - 0.00038 20.0 0.5 0.00083 18.9 0.5 1.6 1 0 0 1 1 1 1 Translocation protein Sec62 CDC45 PF02724.14 RUS81798.1 - 0.00086 17.7 8.8 0.0013 17.2 8.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Connexin PF00029.19 RUS81798.1 - 0.0022 17.8 2.1 0.0053 16.5 2.1 1.6 1 0 0 1 1 1 1 Connexin EMC3_TMCO1 PF01956.16 RUS81798.1 - 0.0061 16.3 5.5 0.8 9.4 0.4 3.2 2 1 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like Zip PF02535.22 RUS81798.1 - 0.0065 15.7 0.3 0.013 14.8 0.3 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter Sin_N PF04801.13 RUS81798.1 - 0.019 14.2 4.0 0.029 13.6 4.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF913 PF06025.12 RUS81798.1 - 0.085 11.8 2.2 0.12 11.3 2.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 RUS81798.1 - 0.13 12.7 6.2 0.21 12.0 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF936 PF06075.12 RUS81798.1 - 0.21 10.5 6.4 0.29 10.0 6.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2207 PF09972.9 RUS81798.1 - 0.68 8.6 7.6 3.6 6.2 0.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RR_TM4-6 PF06459.12 RUS81798.1 - 1.7 8.4 15.1 1.2 8.9 13.4 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 RUS81798.1 - 4.8 7.2 5.7 7.4 6.6 5.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Cdh1_DBD_1 PF18196.1 RUS81798.1 - 6.9 7.0 13.0 13 6.1 12.6 1.5 2 0 0 2 2 1 0 Chromodomain helicase DNA-binding domain 1 BTB_3 PF16017.5 RUS81799.1 - 3.7e-51 171.6 0.0 7.6e-51 170.6 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain BTB_2 PF02214.22 RUS81799.1 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Lectin_C PF00059.21 RUS81800.1 - 2.8e-17 63.4 1.2 3.5e-17 63.1 1.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain MIB_HERC2 PF06701.13 RUS81800.1 - 0.0067 16.6 0.3 0.02 15.1 0.3 1.8 1 0 0 1 1 1 1 Mib_herc2 RRM_1 PF00076.22 RUS81801.1 - 1.4e-65 217.0 3.9 1.9e-18 66.0 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 RUS81801.1 - 3.3e-06 27.0 2.7 0.14 12.0 0.0 4.5 4 1 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 RUS81801.1 - 0.00013 21.8 0.1 0.49 10.3 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RUS81801.1 - 0.00048 20.2 0.0 0.21 11.8 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS81801.1 - 0.1 12.6 0.1 9.6 6.3 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ras PF00071.22 RUS81802.1 - 2.5e-32 111.7 0.0 3.4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS81802.1 - 4.8e-12 46.2 0.0 8.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81802.1 - 1.8e-06 27.5 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 RUS81802.1 - 0.0011 19.4 1.8 0.01 16.2 1.8 2.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RUS81802.1 - 0.0021 18.0 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS81802.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS81802.1 - 0.059 13.6 0.0 0.33 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 RUS81802.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NiFeSe_Hases PF00374.19 RUS81802.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DUF1479 PF07350.12 RUS81804.1 - 0.016 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) BTB PF00651.31 RUS81805.1 - 4.7e-19 68.7 0.4 9.3e-19 67.7 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS81805.1 - 1.9e-18 66.5 1.4 4.5e-15 55.6 0.7 2.5 2 0 0 2 2 2 2 BTB And C-terminal Kelch DUF4024 PF13216.6 RUS81805.1 - 0.062 13.2 0.2 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) UPF0121 PF03661.13 RUS81805.1 - 0.075 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) SE PF08491.10 RUS81805.1 - 0.1 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Squalene epoxidase BIR PF00653.21 RUS81806.1 - 2.1e-59 198.1 13.1 2.7e-22 79.2 1.1 3.9 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS81806.1 - 3.3e-12 46.1 14.8 3.3e-12 46.1 14.8 2.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS81806.1 - 6.2e-05 22.8 14.0 0.0002 21.1 14.0 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.9 RUS81806.1 - 8.3 6.8 9.9 21 5.6 9.9 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_2 PF13639.6 RUS81806.1 - 9.8 6.6 23.9 0.21 12.0 16.1 2.4 3 0 0 3 3 3 0 Ring finger domain DNA_pol_A_exo1 PF01612.20 RUS81807.1 - 8e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Hormone_recep PF00104.30 RUS81808.1 - 5.2e-24 85.0 0.4 2.3e-23 82.9 0.4 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS81808.1 - 4.4e-14 52.7 9.5 7.7e-14 51.9 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CH PF00307.31 RUS81809.1 - 1.2e-11 44.7 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 RUS81809.1 - 2e-11 43.3 4.9 3.6e-11 42.5 4.9 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 RUS81809.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain RVT_1 PF00078.27 RUS81810.1 - 7.2e-10 38.7 2.8 4.9e-06 26.2 0.8 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS81811.1 - 1.5e-12 47.9 0.2 2.7e-11 43.9 0.2 2.2 1 1 0 1 1 1 1 RNase H Rhabdo_ncap PF00945.18 RUS81813.1 - 2.2e-39 135.5 0.0 2.7e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein MULE PF10551.9 RUS81814.1 - 3.7e-16 59.3 0.1 8.5e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF5575 PF17738.1 RUS81814.1 - 1.3e-08 34.2 0.2 3.5e-08 32.9 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5575) DDE_Tnp_ISL3 PF01610.17 RUS81814.1 - 2.4e-07 30.7 1.5 1.1e-06 28.5 1.5 2.3 1 1 0 1 1 1 1 Transposase SWIM PF04434.17 RUS81814.1 - 0.023 14.4 2.0 0.046 13.4 2.0 1.5 1 0 0 1 1 1 0 SWIM zinc finger Fox-1_C PF12414.8 RUS81814.1 - 0.21 12.0 0.5 28 5.2 0.0 2.3 2 0 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal WD40 PF00400.32 RUS81815.1 - 0.0094 16.8 8.6 0.64 11.0 0.2 4.6 3 1 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.15 RUS81815.1 - 0.015 14.7 0.4 0.11 11.8 0.1 2.1 2 0 0 2 2 2 0 CPSF A subunit region CUT PF02376.15 RUS81816.1 - 3.2e-32 110.5 0.5 5.5e-32 109.8 0.5 1.4 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 RUS81816.1 - 7.1e-12 45.0 1.1 1.8e-11 43.7 1.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS81816.1 - 3.9e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Zip PF02535.22 RUS81817.1 - 0.0045 16.3 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SAPS PF04499.15 RUS81817.1 - 0.092 11.5 5.5 0.1 11.4 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 RUS81817.1 - 2.6 7.4 28.3 3.7 6.9 28.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 RUS81817.1 - 7.7 5.2 8.8 9.9 4.8 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 7tm_1 PF00001.21 RUS81818.1 - 1.6e-12 47.3 20.2 1.9e-12 47.1 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS81818.1 - 6.3e-06 25.8 17.5 7.5e-06 25.5 17.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx BRICHOS PF04089.14 RUS81820.1 - 1.7e-05 25.0 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Transpos_assoc PF13963.6 RUS81820.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase-associated domain F-box PF00646.33 RUS81821.1 - 1.5e-06 27.9 0.8 2.5e-06 27.2 0.8 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RUS81821.1 - 1.3e-05 25.0 0.2 2.3e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 RUS81821.1 - 0.0002 21.2 0.4 0.00066 19.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 RUS81821.1 - 0.08 13.3 1.0 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 PRANC domain Ldl_recept_a PF00057.18 RUS81822.1 - 2.1e-55 184.6 111.0 2.6e-11 43.6 11.3 7.1 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 RUS81822.1 - 9e-43 144.5 21.5 1.7e-09 38.0 0.1 10.9 11 2 0 11 11 11 8 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 RUS81822.1 - 4.1e-16 59.0 0.1 7.8e-08 31.9 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF5050) FXa_inhibition PF14670.6 RUS81822.1 - 2.1e-13 50.3 49.0 3.8e-07 30.3 11.3 5.7 6 1 0 6 6 6 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 RUS81822.1 - 2.2e-09 37.3 7.6 0.27 10.8 0.2 7.3 3 3 3 7 7 7 4 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 RUS81822.1 - 3.4e-05 24.0 0.3 2.5 8.4 0.0 6.5 7 1 1 8 8 8 1 Arylesterase Lactonase PF10282.9 RUS81822.1 - 0.061 12.6 0.1 2.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller LPD11 PF18824.1 RUS81823.1 - 0.019 15.0 1.7 0.047 13.8 1.7 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 DUF3474 PF11960.8 RUS81823.1 - 0.28 11.4 6.4 0.82 9.9 6.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) TraV PF09676.10 RUS81823.1 - 1.5 9.8 11.7 4.8 8.2 11.2 2.0 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Ldl_recept_b PF00058.17 RUS81824.1 - 4.3e-36 123.1 0.2 7.3e-13 48.8 0.1 4.2 4 0 0 4 4 4 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 RUS81824.1 - 0.0049 16.5 0.2 0.21 11.1 0.0 2.5 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 RUS81825.1 - 1.2e-25 89.7 10.8 0.00042 20.7 0.2 8.8 8 1 0 8 8 8 6 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 RUS81825.1 - 1.4e-24 86.0 29.8 3e-12 46.5 10.3 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 RUS81825.1 - 3.3e-12 46.4 45.1 4.2e-07 30.1 3.8 4.3 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 RUS81825.1 - 4.1e-07 29.5 0.1 0.021 14.1 0.0 2.9 2 2 0 2 2 2 2 Domain of unknown function (DUF5050) cEGF PF12662.7 RUS81825.1 - 1.2e-06 28.3 16.5 0.0021 17.9 0.6 4.4 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS81825.1 - 0.00014 22.0 10.6 0.00014 22.0 10.6 5.3 4 1 1 5 5 5 2 Calcium-binding EGF domain SGL PF08450.12 RUS81825.1 - 0.00044 19.9 4.5 1.1 8.7 0.3 5.0 3 2 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region GCP_C_terminal PF04130.13 RUS81826.1 - 1.8e-82 277.3 5.0 3.5e-82 276.3 5.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RUS81826.1 - 2.8e-81 273.5 0.7 2.8e-81 273.5 0.7 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal FliT PF05400.13 RUS81826.1 - 0.054 14.3 2.6 2 9.3 0.0 3.1 3 0 0 3 3 3 0 Flagellar protein FliT Cas_Csx8 PF09657.10 RUS81828.1 - 0.25 10.3 0.1 0.33 9.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) Gln-synt_C PF00120.24 RUS81830.1 - 4.7e-69 233.0 0.0 1.1e-68 231.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Viral_Beta_CD PF04530.12 RUS81831.1 - 0.005 17.1 0.3 0.01 16.1 0.3 1.5 1 0 0 1 1 1 1 Viral Beta C/D like family Peptidase_M56 PF05569.11 RUS81831.1 - 0.07 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 SecG PF03840.14 RUS81831.1 - 0.22 11.6 2.1 0.39 10.8 2.1 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit SCIMP PF15050.6 RUS81831.1 - 0.31 11.5 1.3 2.9 8.4 0.4 2.2 2 1 0 2 2 2 0 SCIMP protein 5_nucleotid PF05761.14 RUS81833.1 - 3.5e-36 125.1 0.0 1.2e-26 93.6 0.1 2.1 1 1 1 2 2 2 2 5' nucleotidase family Hydrolase_like PF13242.6 RUS81833.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Caldesmon PF02029.15 RUS81835.1 - 0.0037 16.1 20.4 0.0065 15.3 20.4 1.3 1 0 0 1 1 1 1 Caldesmon CDC45 PF02724.14 RUS81835.1 - 0.02 13.2 17.6 0.031 12.6 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS81835.1 - 0.039 13.8 23.4 0.013 15.4 19.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 RUS81835.1 - 3.1 7.2 22.9 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SID-1_RNA_chan PF13965.6 RUS81835.1 - 3.5 5.9 7.6 5 5.4 7.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 RUS81835.1 - 8.1 4.8 7.2 10 4.4 7.2 1.1 1 0 0 1 1 1 0 Cellulose synthase ALMT PF11744.8 RUS81835.1 - 9.3 5.0 21.0 2.5 6.8 17.2 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter VIR_N PF15912.5 RUS81835.1 - 9.9 5.7 22.6 26 4.3 0.2 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal zf-C2H2 PF00096.26 RUS81837.1 - 2.5e-43 144.2 65.8 3.1e-07 30.5 0.4 9.7 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81837.1 - 2.3e-36 122.6 59.5 5.5e-08 32.9 1.8 11.0 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS81837.1 - 8.6e-32 107.1 64.7 0.00035 21.2 0.7 10.0 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS81837.1 - 9e-13 48.2 35.0 0.00072 19.8 0.3 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS81837.1 - 1e-11 44.4 43.0 0.0005 19.8 2.4 7.6 7 1 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS81837.1 - 3.8e-11 42.7 56.0 0.0037 17.2 0.3 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS81837.1 - 2.5e-08 33.5 45.4 0.072 12.9 0.2 9.1 9 0 0 9 9 9 5 zinc-finger C2H2-type GAGA PF09237.11 RUS81837.1 - 7.7e-06 25.6 19.4 0.044 13.6 0.3 6.5 4 1 2 6 6 6 2 GAGA factor zf-Di19 PF05605.12 RUS81837.1 - 0.0007 19.8 4.0 0.0007 19.8 4.0 5.7 5 1 1 6 6 5 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RUS81837.1 - 0.0058 16.6 41.1 0.018 15.0 0.2 7.2 4 2 2 6 6 6 2 BED zinc finger zf-C2H2_8 PF15909.5 RUS81837.1 - 0.032 14.5 34.7 0.16 12.3 0.5 5.2 3 2 2 5 5 5 0 C2H2-type zinc ribbon zf-met PF12874.7 RUS81837.1 - 0.033 14.6 0.1 0.033 14.6 0.1 8.9 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 RUS81837.1 - 0.28 11.0 3.1 0.91 9.4 0.9 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif BolA PF01722.18 RUS81837.1 - 0.54 10.6 11.2 13 6.1 0.0 5.3 4 1 0 4 4 4 0 BolA-like protein FYVE PF01363.21 RUS81837.1 - 0.58 10.3 42.5 7.2 6.8 0.0 6.2 4 2 0 4 4 4 0 FYVE zinc finger PyrI_C PF02748.15 RUS81837.1 - 0.72 9.8 22.9 0.21 11.5 1.0 5.9 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 RUS81837.1 - 0.93 9.1 31.5 3.1 7.5 0.2 8.0 8 0 0 8 8 7 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS81837.1 - 2.6 8.2 42.7 3.6 7.8 2.1 6.8 4 1 3 7 7 7 0 Zinc ribbon domain UBZ_FAAP20 PF15750.5 RUS81837.1 - 5.9 6.9 10.0 30 4.6 0.1 4.8 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger Actin_micro PF17003.5 RUS81837.1 - 6.8 5.8 17.0 5 6.2 2.3 3.6 2 2 1 3 3 3 0 Putative actin-like family RNB PF00773.19 RUS81839.1 - 4.9e-97 325.2 0.0 6.8e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RUS81839.1 - 1.5e-25 89.0 0.0 4.7e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 RUS81839.1 - 2.5e-21 75.8 0.0 5.8e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal zf-C2H2_assoc2 PF16624.5 RUS81839.1 - 0.091 13.8 0.5 0.22 12.6 0.5 1.6 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger 7tm_1 PF00001.21 RUS81840.1 - 7.9e-11 41.8 10.4 1.1e-10 41.3 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SUR7 PF06687.12 RUS81840.1 - 1.2 8.7 15.5 1.5 8.4 0.6 2.3 2 0 0 2 2 2 0 SUR7/PalI family 7tm_1 PF00001.21 RUS81841.1 - 0.00028 20.3 0.0 0.00059 19.2 0.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS81842.1 - 2.6e-27 95.8 20.5 5.4e-20 71.8 12.9 3.1 3 1 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) CAF1 PF04857.20 RUS81843.1 - 3e-39 135.1 0.1 3.3e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF4517 PF15006.6 RUS81844.1 - 4e-43 147.3 0.2 5e-43 146.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) Myosin_head PF00063.21 RUS81845.1 - 2e-85 287.4 1.1 2.5e-85 287.1 1.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 RUS81845.1 - 1.9e-17 62.8 1.8 3.4e-17 62.0 1.8 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 RUS81845.1 - 0.0037 17.5 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RUS81845.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS81845.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Myosin_head PF00063.21 RUS81846.1 - 2.6e-168 561.3 0.2 9.4e-91 305.0 0.0 4.3 4 1 1 5 5 3 2 Myosin head (motor domain) Myosin_tail_1 PF01576.19 RUS81846.1 - 8.5e-160 533.8 271.5 7.4e-124 414.8 210.1 2.0 1 1 1 2 2 2 2 Myosin tail DUF4472 PF14739.6 RUS81846.1 - 7.2e-05 23.5 15.2 7.2e-05 23.5 15.2 13.3 2 2 8 13 13 12 1 Domain of unknown function (DUF4472) IQ PF00612.27 RUS81846.1 - 0.00028 20.4 3.7 0.0017 18.0 0.5 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif ATG16 PF08614.11 RUS81846.1 - 0.0019 18.5 269.9 0.053 13.7 43.6 10.8 1 1 11 12 12 11 6 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 RUS81846.1 - 0.0027 16.4 23.7 0.0027 16.4 23.7 6.7 1 1 6 7 7 7 4 AAA domain Mce4_CUP1 PF11887.8 RUS81846.1 - 0.003 17.1 3.4 0.003 17.1 3.4 6.3 6 2 0 7 7 7 1 Cholesterol uptake porter CUP1 of Mce4, putative Filament PF00038.21 RUS81846.1 - 0.0039 16.8 44.7 0.0039 16.8 44.7 6.5 1 1 4 5 5 4 3 Intermediate filament protein DUF1664 PF07889.12 RUS81846.1 - 0.0053 16.8 150.7 0.1 12.6 12.8 13.7 2 2 12 14 14 14 7 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RUS81846.1 - 0.0069 16.6 9.1 0.0069 16.6 9.1 11.2 1 1 11 12 12 11 5 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RUS81846.1 - 0.01 14.8 245.5 0.043 12.7 36.2 9.4 1 1 9 10 10 10 7 Spc7 kinetochore protein DUF812 PF05667.11 RUS81846.1 - 2.5 6.9 229.7 0.41 9.5 29.1 6.8 1 1 5 6 6 6 0 Protein of unknown function (DUF812) MscS_porin PF12795.7 RUS81846.1 - 5.2 6.5 237.6 0.16 11.5 49.8 8.4 1 1 7 8 8 7 0 Mechanosensitive ion channel porin domain SSF PF00474.17 RUS81848.1 - 7.7e-32 110.6 26.4 1.3e-31 109.9 26.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Phage_holin_Dp1 PF16938.5 RUS81848.1 - 0.58 10.4 8.5 0.19 12.0 0.6 3.3 3 0 0 3 3 3 0 Putative phage holin Dp-1 RRM_1 PF00076.22 RUS81849.1 - 1.9e-12 46.8 0.0 2.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS81849.1 - 0.039 14.1 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 RUS81849.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP1 PF08601.10 RUS81849.1 - 0.15 11.8 16.9 0.28 10.8 16.9 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 PNISR PF15996.5 RUS81849.1 - 0.6 10.4 11.0 0.92 9.7 11.0 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 RUS81849.1 - 0.6 8.6 16.8 0.68 8.4 16.8 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 RUS81849.1 - 1.1 7.0 13.1 1.2 6.8 13.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 RUS81849.1 - 2.3 7.3 41.2 0.031 13.4 14.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 RUS81849.1 - 9 4.9 9.8 12 4.6 9.8 1.3 1 0 0 1 1 1 0 Presenilin Methyltransf_16 PF10294.9 RUS81850.1 - 3.2e-14 53.0 0.2 5e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase FAM86 PF14904.6 RUS81850.1 - 1.8e-13 50.4 0.1 3.9e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function Methyltransf_12 PF08242.12 RUS81850.1 - 0.00047 20.9 0.0 0.55 11.0 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 RUS81850.1 - 0.0044 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RGS_DHEX PF18148.1 RUS81851.1 - 8.1e-40 135.0 3.2 1.4e-39 134.2 0.8 2.5 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 RUS81851.1 - 9.3e-29 100.1 4.9 2.7e-28 98.6 4.9 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 RUS81851.1 - 2.2e-09 37.3 0.0 5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 RUS81851.1 - 2e-07 30.9 1.6 2.8e-07 30.4 0.1 2.1 2 0 0 2 2 2 1 GGL domain Bap31 PF05529.12 RUS81852.1 - 0.059 13.2 18.3 13 5.7 0.5 5.3 1 1 4 5 5 5 0 Bap31/Bap29 transmembrane region Cpta_toxin PF07254.12 RUS81852.1 - 0.49 10.4 6.5 23 5.0 1.4 3.1 1 1 3 4 4 4 0 Membrane-bound toxin component of toxin-antitoxin system TSGA13 PF14994.6 RUS81852.1 - 4.5 6.6 6.2 47 3.2 0.3 2.9 1 1 1 3 3 3 0 Testis-specific gene 13 protein OHA PF14418.6 RUS81853.1 - 0.0045 16.8 6.8 12 5.8 0.0 4.5 1 1 4 5 5 5 3 OST-HTH Associated domain PTSIIB_sorb PF03830.15 RUS81853.1 - 0.76 10.0 3.8 4.7 7.4 1.9 2.2 1 1 1 2 2 2 0 PTS system sorbose subfamily IIB component SF3b10 PF07189.11 RUS81853.1 - 0.78 9.9 3.4 10 6.3 0.1 3.2 1 1 3 4 4 4 0 Splicing factor 3B subunit 10 (SF3b10) RRM_1 PF00076.22 RUS81854.1 - 8.8e-13 47.9 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 RUS81854.1 - 2.5e-10 40.7 11.1 2.5e-10 40.7 11.1 4.8 2 1 2 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 FYTT PF07078.11 RUS81854.1 - 0.0008 18.8 1.9 0.0008 18.8 1.9 1.6 2 0 0 2 2 2 1 Forty-two-three protein UQ_con PF00179.26 RUS81855.1 - 2.3e-52 176.3 0.0 2.6e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS81855.1 - 0.00031 21.0 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 RUS81855.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 RUS81855.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B LUC7 PF03194.15 RUS81856.1 - 4.1e-27 95.4 14.3 4.1e-27 95.4 14.3 2.1 1 1 1 2 2 2 1 LUC7 N_terminus DUF1682 PF07946.14 RUS81856.1 - 0.39 9.9 12.7 0.24 10.6 11.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 RUS81856.1 - 1 8.0 2.5 0.99 8.1 2.5 1.2 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 RUS81856.1 - 2.1 7.3 14.6 3.2 6.7 14.6 1.2 1 0 0 1 1 1 0 Paf1 LUC7 PF03194.15 RUS81857.1 - 2.1e-48 165.2 22.8 2.1e-48 165.2 22.8 2.2 1 1 1 2 2 2 1 LUC7 N_terminus DUF948 PF06103.11 RUS81857.1 - 0.27 11.5 0.9 0.5 10.7 0.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Thioredoxin PF00085.20 RUS81858.1 - 1.7e-23 82.6 0.4 1.9e-23 82.4 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RUS81858.1 - 1.9e-05 25.0 0.2 8.7e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 RUS81858.1 - 0.00079 19.2 0.3 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 RUS81858.1 - 0.00094 19.1 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RUS81858.1 - 0.001 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RUS81858.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like GTP_EFTU PF00009.27 RUS81859.1 - 3.1e-41 141.0 0.1 6.8e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RUS81859.1 - 1.8e-29 102.3 0.1 1.8e-29 102.3 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RUS81859.1 - 3.1e-09 37.1 0.4 1e-08 35.4 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PAM2 PF07145.15 RUS81859.1 - 0.0043 16.6 7.4 0.031 14.0 0.1 3.1 3 0 0 3 3 3 2 Ataxin-2 C-terminal region MMR_HSR1 PF01926.23 RUS81859.1 - 0.011 15.8 0.0 0.042 13.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cob_adeno_trans PF01923.18 RUS81859.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase PBP1_TM PF14812.6 RUS81859.1 - 4.6 7.7 7.9 0.89 10.0 3.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 RUS81859.1 - 5.6 5.1 7.1 7.6 4.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 RUS81859.1 - 6.3 6.4 7.4 15 5.3 7.4 1.6 1 0 0 1 1 1 0 FAM176 family Apyrase PF06079.11 RUS81860.1 - 5.5e-126 419.7 0.2 6.5e-126 419.4 0.2 1.0 1 0 0 1 1 1 1 Apyrase Ribosomal_L1 PF00687.21 RUS81861.1 - 4.1e-43 147.5 3.2 7.7e-43 146.6 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L25p PF01386.19 RUS81861.1 - 0.11 13.0 0.4 0.71 10.4 0.0 2.4 3 0 0 3 3 3 0 Ribosomal L25p family Rep_fac-A_C PF08646.10 RUS81862.1 - 0.00046 20.0 0.1 0.00071 19.3 0.1 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain DUF1357 PF07094.11 RUS81862.1 - 0.0055 16.8 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1357) MTHFR_C PF12225.8 RUS81862.1 - 0.059 13.0 1.2 0.12 12.0 1.2 1.5 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal CSN8_PSD8_EIF3K PF10075.9 RUS81862.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family CLAMP PF14769.6 RUS81863.1 - 1.7e-05 25.2 2.5 0.00014 22.2 2.5 2.2 1 1 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Utp13 PF08625.11 RUS81863.1 - 0.036 14.0 1.2 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF3818 PF12825.7 RUS81863.1 - 0.21 10.6 2.9 0.25 10.3 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Metallophos PF00149.28 RUS81864.1 - 8.5e-17 62.3 1.0 1.1e-16 61.9 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 RUS81865.1 - 4.9e-17 63.1 4.7 6.8e-17 62.7 4.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Claudin_2 PF13903.6 RUS81866.1 - 0.00016 21.5 10.2 0.0005 19.9 9.8 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 RUS81866.1 - 0.0093 15.0 8.5 0.015 14.3 8.5 1.3 1 0 0 1 1 1 1 Dual oxidase maturation factor CDC45 PF02724.14 RUS81866.1 - 0.061 11.6 2.1 0.085 11.1 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PEMT PF04191.13 RUS81866.1 - 0.081 13.3 0.7 0.081 13.3 0.7 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase Apt1 PF10351.9 RUS81866.1 - 0.21 10.4 4.0 0.24 10.2 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1751 PF08551.10 RUS81866.1 - 0.46 11.1 6.2 18 6.0 4.9 2.6 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Spem1 PF15670.5 RUS81866.1 - 3 7.4 12.9 5.7 6.5 12.9 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 RSRP PF17069.5 RUS81866.1 - 9.3 5.7 28.0 16 5.0 28.0 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Rhomboid PF01694.22 RUS81867.1 - 1.9e-14 53.9 13.5 1.9e-14 53.9 13.5 1.8 2 0 0 2 2 2 1 Rhomboid family Reeler PF02014.16 RUS81868.1 - 1.4e-25 90.5 0.0 3.2e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Reeler domain Cytochrom_B561 PF03188.16 RUS81868.1 - 2e-08 34.4 11.0 2e-08 34.4 11.0 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 RUS81868.1 - 2.6e-06 27.7 0.1 5.1e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 DOMON domain COX15-CtaA PF02628.15 RUS81868.1 - 0.00084 18.5 8.9 0.014 14.5 3.2 2.3 2 0 0 2 2 2 2 Cytochrome oxidase assembly protein Dicty_CTDC PF00526.18 RUS81868.1 - 0.67 9.9 4.2 0.33 10.9 0.5 2.2 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat DUF4079 PF13301.6 RUS81868.1 - 5 7.3 14.8 9.1 6.4 13.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) PepSY_TM PF03929.16 RUS81868.1 - 6.1 6.4 12.9 2.6 7.6 4.6 2.5 2 0 0 2 2 2 0 PepSY-associated TM region Pox_I5 PF04713.12 RUS81868.1 - 9 6.4 10.8 0.38 10.8 3.7 2.4 3 0 0 3 3 3 0 Poxvirus protein I5 Reeler PF02014.16 RUS81869.1 - 3.1e-20 73.2 0.1 4.2e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Reeler domain Tash_PEST PF07708.11 RUS81869.1 - 0.026 14.7 1.1 0.041 14.0 1.1 1.3 1 0 0 1 1 1 0 Tash protein PEST motif DOMON PF03351.17 RUS81870.1 - 9.8e-12 45.2 0.6 1.7e-11 44.4 0.1 1.6 2 0 0 2 2 2 1 DOMON domain DUF4079 PF13301.6 RUS81870.1 - 1.2 9.2 18.8 1.9 8.6 16.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Neur_chan_LBD PF02931.23 RUS81871.1 - 5.8e-48 163.2 2.2 8.2e-48 162.7 2.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS81871.1 - 2.9e-47 161.8 3.1 1.4e-46 159.5 3.1 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RVT_1 PF00078.27 RUS81873.1 - 0.0011 18.5 0.1 0.0025 17.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Xan_ur_permease PF00860.20 RUS81874.1 - 7.8e-65 219.1 36.6 2.1e-58 197.9 24.7 2.1 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 RUS81874.1 - 1.9 8.9 18.6 0.66 10.4 0.6 3.6 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily DUF4573 PF15140.6 RUS81876.1 - 1.3e-09 38.1 41.8 0.0034 17.2 11.8 3.4 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) Collagen PF01391.18 RUS81876.1 - 0.016 15.0 1.2 0.016 15.0 1.2 1.6 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DOMON PF03351.17 RUS81877.1 - 4.7e-29 101.1 0.1 7.5e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cu2_monooxygen PF01082.20 RUS81877.1 - 1.7e-18 67.1 0.1 3.7e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain CDH-cyt PF16010.5 RUS81877.1 - 7.8e-07 28.9 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Glyco_transf_10 PF00852.19 RUS81878.1 - 9.9e-95 315.3 6.2 1.9e-52 177.6 1.9 3.0 4 0 0 4 4 4 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS81878.1 - 3.2e-43 146.7 2.9 5.2e-21 75.2 0.3 2.8 2 0 0 2 2 2 2 Fucosyltransferase, N-terminal TsaE PF02367.17 RUS81878.1 - 0.00057 19.9 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2240 PF09999.9 RUS81878.1 - 0.025 14.2 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) DUF262 PF03235.14 RUS81878.1 - 0.026 14.7 1.4 7.7 6.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF262 Docking PF08990.11 RUS81878.1 - 0.03 14.0 0.2 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Erythronolide synthase docking DUF5358 PF17311.2 RUS81878.1 - 0.043 13.8 1.2 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5358) DEP PF00610.21 RUS81878.1 - 0.24 11.5 3.5 16 5.7 0.1 2.9 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Adeno_E4_34 PF04528.13 RUS81878.1 - 0.44 10.4 3.0 20 5.0 0.1 2.8 3 0 0 3 3 3 0 Adenovirus early E4 34 kDa protein conserved region ADAM_CR PF08516.12 RUS81878.1 - 0.57 10.6 5.6 13 6.2 0.6 2.5 2 0 0 2 2 2 0 ADAM cysteine-rich Jnk-SapK_ap_N PF09744.9 RUS81878.1 - 2.8 8.2 6.7 17 5.6 0.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DDE_Tnp_IS1595 PF12762.7 RUS81879.1 - 6.8e-14 52.1 0.0 7.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain TPR_12 PF13424.6 RUS81881.1 - 1.6e-07 31.5 0.4 2.7e-05 24.4 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS81881.1 - 0.00088 19.2 1.5 0.0019 18.1 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS81881.1 - 0.0011 18.7 1.5 0.0026 17.5 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS81881.1 - 0.011 16.5 0.1 1.4 10.0 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS81881.1 - 0.013 15.4 0.6 0.039 13.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS81881.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 MalT-like TPR region TPR_11 PF13414.6 RUS81881.1 - 0.066 12.9 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 RUS81881.1 - 0.34 11.2 1.5 0.54 10.6 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.18 RUS81882.1 - 5.3e-10 39.2 13.5 1e-09 38.3 13.5 1.5 1 0 0 1 1 1 1 MYND finger SET PF00856.28 RUS81882.1 - 3.5e-05 24.3 0.0 4.6e-05 23.9 0.0 1.2 1 1 0 1 1 1 1 SET domain PolC_DP2 PF03833.13 RUS81882.1 - 0.2 9.5 1.9 0.26 9.1 1.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 RUS81882.1 - 0.45 10.8 8.6 1.4 9.3 8.6 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 RUS81883.1 - 1.6e-18 66.8 26.6 7.1e-18 64.6 26.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS81883.1 - 5.4 5.8 20.0 2.4 6.9 6.8 2.9 1 1 0 2 2 2 0 MFS_1 like family Acyl_transf_3 PF01757.22 RUS81884.1 - 6.2e-21 74.8 31.2 4.2e-18 65.5 11.2 2.1 1 1 1 2 2 2 2 Acyltransferase family RT_RNaseH_2 PF17919.1 RUS81885.1 - 6.7e-34 115.9 0.0 1.1e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS81885.1 - 8.5e-31 106.4 0.0 1.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS81885.1 - 3.4e-22 79.1 0.1 6e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS81885.1 - 1.1e-12 47.9 0.1 2e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4031 PF13223.6 RUS81885.1 - 0.021 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Acyl_transf_3 PF01757.22 RUS81886.1 - 4.1e-10 39.2 16.5 5.7e-10 38.8 8.1 2.2 2 0 0 2 2 2 2 Acyltransferase family Acyl_transf_3 PF01757.22 RUS81887.1 - 0.00068 18.8 8.0 0.00068 18.8 8.0 3.1 2 1 1 3 3 3 2 Acyltransferase family Bac_export_3 PF01313.19 RUS81887.1 - 0.067 13.1 4.7 0.69 9.9 0.1 3.1 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Palm_thioest PF02089.15 RUS81888.1 - 1e-60 205.6 0.0 1.2e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 RUS81888.1 - 0.0029 17.4 0.1 0.0069 16.1 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 RUS81888.1 - 0.01 15.3 0.3 0.038 13.5 0.3 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RUS81888.1 - 0.082 13.5 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 RUS81888.1 - 0.18 11.3 0.0 0.69 9.4 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) O-FucT PF10250.9 RUS81889.1 - 1.8e-74 251.4 0.0 2.2e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase IRF PF00605.17 RUS81892.1 - 8.8e-29 99.9 0.2 1.7e-28 99.0 0.2 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 RUS81892.1 - 4e-17 62.6 0.3 7.4e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Interferon-regulatory factor 3 Aldo_ket_red PF00248.21 RUS81893.1 - 1.5e-71 241.0 0.0 2e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SURF1 PF02104.15 RUS81894.1 - 6.6e-41 140.5 0.0 8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Prefoldin_2 PF01920.20 RUS81895.1 - 9.5e-22 77.0 10.7 1.2e-21 76.6 10.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DHHW PF14286.6 RUS81895.1 - 0.0024 17.2 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 DHHW protein DHR10 PF18595.1 RUS81895.1 - 0.0034 17.4 1.4 0.0034 17.4 1.4 2.2 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF4763 PF15960.5 RUS81895.1 - 0.032 13.5 11.2 0.12 11.7 11.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Fib_alpha PF08702.10 RUS81895.1 - 0.039 14.1 9.0 0.1 12.8 8.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CorA PF01544.18 RUS81895.1 - 0.049 12.9 3.6 0.058 12.7 3.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 RUS81895.1 - 0.071 13.2 12.3 0.097 12.8 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 RUS81895.1 - 0.073 13.3 11.7 0.82 9.9 4.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.6 RUS81895.1 - 0.083 13.3 13.5 0.36 11.2 8.2 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Prefoldin PF02996.17 RUS81895.1 - 0.1 12.5 13.2 8.1 6.4 13.2 3.3 1 1 0 1 1 1 0 Prefoldin subunit Syntaxin-6_N PF09177.11 RUS81895.1 - 0.1 13.2 4.0 0.96 10.0 1.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 RUS81895.1 - 0.1 12.6 9.0 0.065 13.3 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS81895.1 - 0.11 11.4 12.4 0.12 11.2 12.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HeLo PF14479.6 RUS81895.1 - 0.14 12.0 5.1 0.15 11.9 5.1 1.0 1 0 0 1 1 1 0 Prion-inhibition and propagation GreA_GreB_N PF03449.15 RUS81895.1 - 0.17 12.1 8.4 1.6 9.0 0.7 3.5 2 2 1 3 3 3 0 Transcription elongation factor, N-terminal XhlA PF10779.9 RUS81895.1 - 0.21 11.8 6.5 0.074 13.3 2.1 2.4 3 1 0 3 3 2 0 Haemolysin XhlA Rx_N PF18052.1 RUS81895.1 - 0.26 11.6 9.6 0.55 10.5 1.4 2.3 1 1 1 2 2 2 0 Rx N-terminal domain DUF724 PF05266.14 RUS81895.1 - 0.27 11.1 8.1 0.42 10.4 8.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 RUS81895.1 - 0.28 11.2 3.9 0.15 12.1 1.1 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 RUS81895.1 - 0.33 11.3 11.5 0.12 12.7 5.7 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein FliD_C PF07195.12 RUS81895.1 - 0.48 9.8 6.2 1.4 8.3 6.2 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sec34 PF04136.15 RUS81895.1 - 0.55 10.1 6.4 2.1 8.2 1.3 2.1 1 1 1 2 2 2 0 Sec34-like family CREPT PF16566.5 RUS81895.1 - 0.57 10.4 8.1 1.1 9.4 2.9 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Sulfatase_C PF14707.6 RUS81895.1 - 0.62 10.8 2.6 0.45 11.3 0.8 1.8 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Spectrin PF00435.21 RUS81895.1 - 1.1 9.8 14.4 1.8 9.1 6.2 2.4 1 1 1 2 2 2 0 Spectrin repeat YscO PF07321.12 RUS81895.1 - 1.4 8.8 16.3 5.3 7.0 2.8 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO IZUMO PF15005.6 RUS81895.1 - 1.5 9.3 8.5 0.71 10.4 2.6 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF3496 PF12001.8 RUS81895.1 - 2.1 8.8 7.1 4.2 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) FlaC_arch PF05377.11 RUS81895.1 - 2.2 8.7 9.0 0.98 9.9 0.2 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 RUS81895.1 - 2.4 8.7 6.9 10 6.8 0.7 2.7 1 1 1 2 2 2 0 YtxH-like protein Med4 PF10018.9 RUS81895.1 - 3 7.5 13.5 0.19 11.4 6.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3450 PF11932.8 RUS81895.1 - 3.6 6.8 13.9 0.37 10.1 7.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 RUS81895.1 - 4.1 6.7 9.2 7.6 5.8 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nup88 PF10168.9 RUS81895.1 - 5.2 4.8 12.3 18 2.9 12.3 1.7 1 1 0 1 1 1 0 Nuclear pore component Vir_act_alpha_C PF10400.9 RUS81895.1 - 5.4 7.8 9.0 1.2 9.9 1.3 2.9 2 2 1 3 3 3 0 Virulence activator alpha C-term TMPIT PF07851.13 RUS81895.1 - 6.2 6.0 10.1 1.3 8.2 5.9 1.8 1 1 1 2 2 2 0 TMPIT-like protein WDCP PF15390.6 RUS81896.1 - 0.67 8.3 5.1 0.78 8.1 5.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PH PF00169.29 RUS81897.1 - 0.001 19.5 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 PH domain Methyltransf_32 PF13679.6 RUS81898.1 - 9.9e-28 97.1 3.2 1.7e-27 96.4 3.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS81898.1 - 0.00092 19.0 0.3 0.0051 16.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS81898.1 - 0.0077 16.9 0.1 0.029 15.1 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS81898.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain VWC PF00093.18 RUS81899.1 - 3.2e-128 418.1 433.7 8.2e-11 42.1 16.5 21.2 20 2 1 21 21 21 19 von Willebrand factor type C domain VWD PF00094.25 RUS81899.1 - 2e-33 115.9 0.0 4.6e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain TILa PF12714.7 RUS81899.1 - 4.6e-21 74.5 326.6 7.7e-06 25.8 9.3 21.9 20 3 2 23 23 23 16 TILa domain VWC PF00093.18 RUS81900.1 - 3.4e-14 52.9 61.3 4.4e-09 36.5 16.9 4.3 4 0 0 4 4 4 3 von Willebrand factor type C domain Tyrosinase PF00264.20 RUS81900.1 - 1.2e-12 48.6 0.5 2.5e-05 24.7 0.3 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase TILa PF12714.7 RUS81900.1 - 7.5e-05 22.6 8.7 7.5e-05 22.6 8.7 3.6 3 1 0 4 4 4 2 TILa domain Kunitz_BPTI PF00014.23 RUS81901.1 - 1.4e-31 108.4 15.3 6.2e-16 58.4 7.8 3.3 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain EGF PF00008.27 RUS81901.1 - 3.9e-06 27.1 4.3 3.9e-06 27.1 4.3 4.9 6 0 0 6 6 6 1 EGF-like domain VWC PF00093.18 RUS81901.1 - 0.0033 17.7 11.7 0.0033 17.7 11.7 5.1 5 1 0 5 5 5 2 von Willebrand factor type C domain Laminin_G_2 PF02210.24 RUS81901.1 - 0.026 15.1 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain FlaC_arch PF05377.11 RUS81901.1 - 0.19 12.2 0.1 0.6 10.5 0.1 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sugar_tr PF00083.24 RUS81902.1 - 6.7e-28 97.8 16.7 8.6e-28 97.4 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS81902.1 - 8.7e-28 97.3 50.1 1.6e-23 83.2 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ_C PF01556.18 RUS81903.1 - 1.3e-40 138.9 0.1 1.7e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS81903.1 - 1.9e-26 92.0 1.8 3e-26 91.3 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain CD225 PF04505.12 RUS81904.1 - 0.01 16.0 0.9 0.015 15.4 0.9 1.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Abhydrolase_9_N PF15420.6 RUS81904.1 - 0.098 12.7 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Hairy_orange PF07527.13 RUS81905.1 - 6.3e-08 32.7 0.2 1.4e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 Hairy Orange Ras PF00071.22 RUS81907.1 - 2.4e-30 105.3 0.0 1.5e-29 102.7 0.0 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 RUS81907.1 - 8.9e-21 74.3 0.0 1.7e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS81907.1 - 4.9e-07 29.4 0.0 6.9e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS81907.1 - 0.00022 20.8 0.0 0.012 15.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 RUS81907.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 RUS81907.1 - 0.043 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RUS81907.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS81907.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1676 PF07898.13 RUS81908.1 - 3.7e-05 23.9 0.1 3.7e-05 23.9 0.1 4.4 4 1 0 4 4 2 1 Protein of unknown function (DUF1676) CDC45 PF02724.14 RUS81908.1 - 0.00024 19.6 12.6 0.00024 19.6 12.6 2.4 2 1 0 2 2 1 1 CDC45-like protein PBP1_TM PF14812.6 RUS81908.1 - 0.016 15.5 14.6 0.016 15.5 14.6 7.2 3 3 3 6 6 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 RUS81908.1 - 0.024 13.2 47.9 0.036 12.6 19.8 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SARAF PF06682.12 RUS81908.1 - 0.028 14.1 0.1 0.028 14.1 0.1 3.7 1 1 1 3 3 2 0 SOCE-associated regulatory factor of calcium homoeostasis YfhO PF09586.10 RUS81908.1 - 0.13 10.4 9.9 0.19 9.9 9.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SDA1 PF05285.12 RUS81908.1 - 0.17 11.3 55.3 0.16 11.4 20.6 2.3 2 0 0 2 2 2 0 SDA1 Vfa1 PF08432.10 RUS81908.1 - 0.19 12.1 20.2 1 9.7 5.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RNase_H2_suC PF08615.11 RUS81908.1 - 0.28 11.4 13.4 0.76 9.9 0.1 3.5 1 1 1 2 2 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Orf78 PF06024.12 RUS81908.1 - 0.59 10.5 0.1 0.59 10.5 0.1 6.0 3 1 1 4 4 3 0 Orf78 (ac78) DUF2070 PF09843.9 RUS81908.1 - 1 7.6 18.5 1.8 6.8 18.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Afi1 PF07792.12 RUS81908.1 - 3.6 8.1 28.3 4.1 7.9 10.1 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4484 PF14831.6 RUS81908.1 - 8.9 6.3 26.9 0.16 12.0 7.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Glyco_transf_92 PF01697.27 RUS81909.1 - 1.7e-10 41.0 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS81909.1 - 0.0008 19.9 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 RUS81910.1 - 4e-07 30.0 0.0 4.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Sulfotransfer_1 PF00685.27 RUS81911.1 - 7.7e-27 94.4 0.0 9.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS81911.1 - 3.7e-12 47.1 0.0 6.5e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family NAD_binding_10 PF13460.6 RUS81912.1 - 3.1e-05 23.9 0.9 11 5.9 0.0 4.6 1 1 7 8 8 8 3 NAD(P)H-binding THEG PF14912.6 RUS81912.1 - 8.3e-05 23.0 5.4 1.2e+02 3.2 5.4 6.1 1 1 0 1 1 1 0 Testicular haploid expressed repeat Big_9 PF17963.1 RUS81912.1 - 0.0032 18.2 19.2 27 5.6 1.2 6.9 1 1 2 3 3 3 1 Bacterial Ig domain DUF1964 PF09244.10 RUS81912.1 - 0.025 15.0 1.1 9.5 6.7 0.0 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF1964) PGC7_Stella PF15549.6 RUS81912.1 - 0.62 10.0 5.8 1.9 8.5 0.1 3.0 1 1 2 3 3 3 0 PGC7/Stella/Dppa3 domain VWA PF00092.28 RUS81913.1 - 4.9e-123 407.9 14.1 2.6e-47 161.3 0.3 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS81913.1 - 4.7e-47 159.1 4.2 6.8e-17 62.1 0.1 3.8 4 0 0 4 4 4 3 von Willebrand factor type A domain VWA_3 PF13768.6 RUS81913.1 - 9.3e-22 77.6 0.0 2.6e-08 33.9 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS81913.1 - 2.5e-07 30.3 1.0 2.2e-05 24.0 0.0 3.5 3 1 0 3 3 3 1 VWA domain containing CoxE-like protein ShK PF01549.24 RUS81913.1 - 9.4e-05 22.9 7.8 9.4e-05 22.9 7.8 4.7 5 0 0 5 5 5 2 ShK domain-like vWA-TerF-like PF10138.9 RUS81913.1 - 0.0017 18.5 2.0 1.6 8.8 0.1 3.2 3 0 0 3 3 3 2 vWA found in TerF C terminus Copine PF07002.16 RUS81913.1 - 0.0074 15.8 1.5 4.1 6.8 0.0 3.0 3 0 0 3 3 3 2 Copine VWC PF00093.18 RUS81913.1 - 0.0077 16.5 11.0 0.0077 16.5 11.0 5.3 5 0 0 5 5 5 3 von Willebrand factor type C domain PatG_C PF18065.1 RUS81913.1 - 0.14 12.1 1.2 5.6 7.0 0.0 2.9 3 0 0 3 3 3 0 PatG C-terminal DUF4573 PF15140.6 RUS81914.1 - 0.0096 15.7 1.9 0.01 15.6 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Comm PF15957.5 RUS81914.1 - 0.1 13.0 7.2 1.3 9.4 0.4 2.5 1 1 1 2 2 2 0 Commissureless DUF3396 PF11876.8 RUS81914.1 - 0.13 11.7 0.2 4.2 6.8 0.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3396) Retinal PF15449.6 RUS81914.1 - 0.13 10.0 13.4 0.15 9.8 13.4 1.0 1 0 0 1 1 1 0 Retinal protein LNP1 PF15419.6 RUS81914.1 - 0.81 9.9 2.1 34 4.6 2.1 2.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 DUF1556 PF07590.11 RUS81914.1 - 2.3 8.6 5.3 18 5.7 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) MFS18 PF17352.2 RUS81914.1 - 4.9 7.6 8.4 2.6 8.4 1.7 2.1 1 1 1 2 2 2 0 Male Flower Specific protein 18 7TM_GPCR_Srw PF10324.9 RUS81915.1 - 3.2e-08 33.2 10.5 6.6e-08 32.2 10.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 RUS81915.1 - 0.00029 20.6 7.2 0.00029 20.6 7.2 2.2 2 1 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 RUS81915.1 - 0.00053 19.7 6.9 0.00053 19.7 6.9 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Abhydrolase_9_N PF15420.6 RUS81915.1 - 0.062 13.3 0.4 0.098 12.6 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus 7TM_GPCR_Srt PF10321.9 RUS81915.1 - 0.11 11.4 13.7 0.49 9.3 10.0 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srsx PF10320.9 RUS81915.1 - 0.3 10.4 17.9 4.5 6.6 17.9 2.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx RhoGEF PF00621.20 RUS81917.1 - 1.1e-44 152.8 2.5 2.1e-44 151.9 2.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 RUS81917.1 - 3.9e-06 27.3 0.0 8.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 RUS81917.1 - 0.073 12.9 0.6 0.98 9.2 0.6 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Gly_transf_sug PF04488.15 RUS81918.1 - 1.8e-07 31.7 0.0 4.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS81918.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 RUS81918.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Nucleotid_trans PF03407.16 RUS81918.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Pkinase PF00069.25 RUS81919.1 - 3.4e-54 184.0 0.2 2.6e-52 177.8 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS81919.1 - 1.4e-28 99.9 0.2 2.8e-28 98.9 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS81919.1 - 0.0011 19.0 0.0 0.0076 16.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS81919.1 - 0.002 17.5 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS81919.1 - 0.0034 16.4 0.2 0.0072 15.3 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 RUS81919.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YcxB PF14317.6 RUS81919.1 - 0.12 12.1 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 YcxB-like protein DUF697 PF05128.12 RUS81920.1 - 1.3e-06 28.2 2.5 0.017 14.8 0.4 3.5 1 1 3 4 4 4 4 Domain of unknown function (DUF697) EpuA PF11772.8 RUS81920.1 - 3.6e-06 26.6 0.1 1.2e+02 2.5 0.0 7.5 3 2 7 12 12 12 0 DNA-directed RNA polymerase subunit beta Omega_Repress PF07764.11 RUS81920.1 - 8.9e-05 23.0 4.7 7.1 7.3 0.0 4.9 1 1 4 6 6 6 2 Omega Transcriptional Repressor YpjP PF14005.6 RUS81920.1 - 0.00011 22.3 0.0 0.2 11.7 0.0 3.5 1 1 3 4 4 4 3 YpjP-like protein LBP_BPI_CETP PF01273.25 RUS81920.1 - 0.00036 20.2 1.8 5.2 6.6 0.2 4.2 1 1 3 4 4 4 2 LBP / BPI / CETP family, N-terminal domain DUF445 PF04286.12 RUS81920.1 - 0.0024 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Sigma54_AID PF00309.20 RUS81920.1 - 0.004 17.0 24.7 23 4.9 0.2 9.3 2 2 8 12 12 12 0 Sigma-54 factor, Activator interacting domain (AID) Dsl1_N PF11988.8 RUS81920.1 - 0.0042 16.1 0.1 2.1 7.2 0.1 2.8 1 1 2 3 3 3 1 Retrograde transport protein Dsl1 N terminal DUF1414 PF07208.11 RUS81920.1 - 0.007 16.3 20.0 39 4.3 0.1 9.7 3 2 6 11 11 11 0 Protein of unknown function (DUF1414) GerPC PF10737.9 RUS81920.1 - 0.03 14.4 1.0 0.57 10.2 0.8 2.2 1 1 1 2 2 2 0 Spore germination protein GerPC FlgO PF17680.1 RUS81920.1 - 0.078 12.7 4.9 17 5.1 0.2 4.1 1 1 2 3 3 3 0 FlgO protein FHIPEP PF00771.20 RUS81920.1 - 0.2 10.1 5.8 0.85 8.0 5.7 2.0 1 1 0 1 1 1 0 FHIPEP family SHS2_Rpb7-N PF03876.17 RUS81920.1 - 0.41 11.0 12.7 42 4.6 0.5 6.1 1 1 2 3 3 3 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3060 PF11259.8 RUS81921.1 - 1.3e-07 31.2 1.5 0.017 14.8 0.1 3.5 1 1 3 4 4 4 4 Protein of unknown function (DUF3060) TLD PF07534.16 RUS81921.1 - 0.0012 19.1 7.8 1.4 9.1 0.8 3.2 1 1 2 3 3 3 3 TLD DUF5597 PF18120.1 RUS81921.1 - 0.0043 17.2 4.0 4.8 7.3 0.6 3.9 1 1 2 3 3 3 1 Domain of unknown function (DUF5597) DUF3942 PF13078.6 RUS81921.1 - 0.0045 17.3 0.8 9.4 6.5 0.1 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3942) NUT PF12881.7 RUS81921.1 - 0.0084 14.6 0.0 1.7 6.9 0.0 2.0 1 1 1 2 2 2 2 NUT protein Phage_TTP_11 PF16460.5 RUS81921.1 - 0.33 10.8 4.8 5.3 6.9 0.5 2.4 1 1 1 2 2 2 0 Phage tail tube, TTP, lambda-like PriCT_1 PF08708.11 RUS81921.1 - 1.9 8.3 14.4 34 4.3 0.1 5.8 2 2 6 8 8 8 0 Primase C terminal 1 (PriCT-1) Caprin-1_dimer PF18293.1 RUS81922.1 - 8e-38 129.5 0.2 8e-38 129.5 0.2 2.0 2 0 0 2 2 2 1 Caprin-1 dimerization domain Cupin_8 PF13621.6 RUS81923.1 - 2e-62 211.2 0.9 3.8e-62 210.3 0.9 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RUS81923.1 - 0.014 14.9 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Cupin superfamily protein AAA_31 PF13614.6 RUS81923.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF4211 PF13926.6 RUS81924.1 - 0.00065 19.8 0.3 0.00065 19.8 0.3 2.5 3 1 1 4 4 4 1 Domain of unknown function (DUF4211) DUF5320 PF17253.2 RUS81924.1 - 0.056 14.5 0.4 0.056 14.5 0.4 3.6 2 1 0 2 2 2 0 Family of unknown function (DUF5320) RXT2_N PF08595.11 RUS81924.1 - 1.3 9.1 13.7 3.9 7.5 5.6 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal FXMRP1_C_core PF12235.8 RUS81924.1 - 1.8 9.2 44.8 3.1 8.4 11.3 3.7 1 1 2 3 3 3 0 Fragile X-related 1 protein core C terminal BSP_II PF05432.11 RUS81924.1 - 3.9 7.1 26.5 7.3 6.2 26.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 RUS81924.1 - 8.2 6.1 20.5 1.2 8.8 11.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Serpin PF00079.20 RUS81925.1 - 8.2e-120 400.5 0.2 9.2e-120 400.3 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Asparaginase_2 PF01112.18 RUS81926.1 - 1.8e-81 273.5 0.3 2e-81 273.4 0.3 1.0 1 0 0 1 1 1 1 Asparaginase FAD_binding_6 PF00970.24 RUS81927.1 - 4.7e-36 123.1 0.0 6.7e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RUS81927.1 - 7.5e-35 119.9 0.0 1.2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RUS81927.1 - 0.00011 22.3 0.0 0.0017 18.5 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF5318 PF17249.2 RUS81928.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Frag1 PF10277.9 RUS81929.1 - 7.7e-23 81.2 3.6 9.5e-23 80.9 3.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Hydrolase_6 PF13344.6 RUS81930.1 - 6.4e-28 96.8 0.0 1.2e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS81930.1 - 2e-20 72.7 0.0 3.4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 RUS81930.1 - 5.3e-14 53.0 0.0 7.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RUS81930.1 - 3.1e-10 40.4 0.2 2.8e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RUS81930.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 RUS81930.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CBM_14 PF01607.24 RUS81931.1 - 0.53 10.5 27.7 20 5.4 0.3 6.5 1 1 4 5 5 5 0 Chitin binding Peritrophin-A domain LSR PF05624.14 RUS81931.1 - 0.75 9.8 41.4 3 7.9 4.8 4.4 1 1 3 4 4 4 0 Lipolysis stimulated receptor (LSR) Acetyltransf_1 PF00583.25 RUS81932.1 - 8.6e-08 32.4 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family COP-gamma_platf PF08752.10 RUS81932.1 - 0.0019 18.4 0.3 0.0029 17.7 0.3 1.3 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain FR47 PF08445.10 RUS81932.1 - 0.0049 16.8 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RUS81932.1 - 0.0052 17.2 0.0 0.0094 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS81932.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ODC_AZ PF02100.17 RUS81932.1 - 0.048 13.6 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Adenylsucc_synt PF00709.21 RUS81933.1 - 5.3e-116 388.0 0.0 5.9e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3106 PF11304.8 RUS81933.1 - 0.017 15.6 0.0 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DERM PF14704.6 RUS81934.1 - 1.3e-41 142.6 6.1 1.5e-41 142.4 6.1 1.0 1 0 0 1 1 1 1 Dermatopontin OSK PF17182.4 RUS81934.1 - 0.059 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 OSK domain DERM PF14704.6 RUS81936.1 - 2.5e-39 135.2 3.3 3e-39 134.9 3.3 1.0 1 0 0 1 1 1 1 Dermatopontin zf-C2H2 PF00096.26 RUS81937.1 - 2e-13 50.0 12.1 4.3e-07 30.0 3.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS81937.1 - 1.3e-10 41.2 17.8 1.8e-09 37.6 3.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS81937.1 - 4.7e-10 39.4 10.1 3.8e-05 24.2 2.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS81937.1 - 1.7e-06 27.8 6.4 0.0034 17.3 1.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS81937.1 - 0.0025 18.1 5.3 0.14 12.5 1.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS81937.1 - 0.004 17.4 3.5 0.035 14.4 3.5 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RUS81937.1 - 0.0043 16.8 7.9 0.075 12.8 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RUS81937.1 - 0.0071 16.6 3.7 0.011 16.0 3.7 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 RUS81937.1 - 0.0091 15.9 5.2 0.82 9.7 0.2 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf_UBZ PF18439.1 RUS81937.1 - 0.014 14.9 0.5 0.28 10.8 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS81937.1 - 0.023 15.1 2.8 0.49 10.9 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 RUS81937.1 - 0.035 14.0 1.3 9.2 6.3 0.0 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Elf1 PF05129.13 RUS81937.1 - 0.042 13.9 1.8 0.059 13.4 1.8 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FOXP-CC PF16159.5 RUS81937.1 - 0.074 13.7 3.4 3.6 8.3 0.3 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF2225 PF09986.9 RUS81937.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-DNL PF05180.12 RUS81937.1 - 0.12 12.3 1.5 0.2 11.6 1.5 1.4 1 1 0 1 1 1 0 DNL zinc finger zf_C2H2_ZHX PF18387.1 RUS81937.1 - 0.19 11.4 3.3 2.4 7.9 0.6 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 RUS81937.1 - 0.31 11.4 4.5 1.4 9.3 1.8 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS81937.1 - 0.4 10.8 2.9 1 9.6 2.9 1.8 1 1 0 1 1 1 0 Zinc ribbon domain NOA36 PF06524.12 RUS81937.1 - 0.82 8.9 11.5 1.2 8.3 11.5 1.3 1 1 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 RUS81937.1 - 9.8 6.9 12.2 25 5.6 11.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Scramblase PF03803.15 RUS81938.1 - 8.9e-28 97.1 0.2 1e-27 96.9 0.2 1.0 1 0 0 1 1 1 1 Scramblase ASC PF00858.24 RUS81939.1 - 1.2e-84 284.9 0.0 1.7e-84 284.4 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Spectrin PF00435.21 RUS81940.1 - 2.6e-21 76.1 18.6 5.7e-15 55.7 14.0 2.1 2 0 0 2 2 2 2 Spectrin repeat FIVAR PF07554.13 RUS81940.1 - 0.0015 19.2 0.1 0.0042 17.8 0.1 1.8 1 0 0 1 1 1 1 FIVAR domain DUF2353 PF09789.9 RUS81940.1 - 0.0058 16.0 9.1 0.0058 16.0 9.1 1.6 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) JHY PF15261.6 RUS81940.1 - 0.68 10.6 10.5 0.47 11.2 1.4 2.4 2 1 0 2 2 2 0 Jhy protein MAS20 PF02064.15 RUS81940.1 - 0.81 9.8 7.0 0.15 12.2 2.2 1.9 1 1 1 2 2 2 0 MAS20 protein import receptor Histone_HNS PF00816.21 RUS81940.1 - 0.91 10.4 5.0 0.47 11.3 2.4 1.9 2 0 0 2 2 2 0 H-NS histone family ADH_zinc_N PF00107.26 RUS81941.1 - 2e-15 56.9 0.0 3.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS81941.1 - 4.6e-07 30.9 0.0 8.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS81941.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF547 PF04784.14 RUS81942.1 - 1.4e-34 118.8 0.0 2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Aldo_ket_red PF00248.21 RUS81944.1 - 3.2e-54 184.1 0.0 6.3e-54 183.2 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family API5 PF05918.11 RUS81945.1 - 3.3e-171 570.6 0.0 4.9e-171 570.1 0.0 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 RUS81945.1 - 1.8e-05 25.0 0.0 0.002 18.5 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 RUS81945.1 - 4.3e-05 22.3 0.5 0.00027 19.7 0.5 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RUS81945.1 - 0.00018 21.6 1.7 0.003 17.6 1.1 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RUS81945.1 - 0.04 14.2 0.0 0.41 11.0 0.1 2.8 3 0 0 3 3 3 0 HEAT repeat Itfg2 PF15907.5 RUS81946.1 - 1.6e-118 395.6 0.1 2.1e-61 207.8 0.0 3.1 2 1 1 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 RUS81946.1 - 8.2e-11 41.9 0.0 0.017 15.1 0.0 3.5 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 RUS81946.1 - 8e-05 23.2 0.4 4 8.1 0.1 3.8 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella COesterase PF00135.28 RUS81948.1 - 6e-140 467.5 0.0 6.8e-140 467.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS81948.1 - 8.9e-08 32.2 0.0 3.2e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS81948.1 - 0.048 13.1 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Guanylate_cyc PF00211.20 RUS81949.1 - 1.8e-62 210.2 0.0 3.4e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 RUS81949.1 - 5e-47 160.7 0.0 1.5e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS81949.1 - 4.1e-35 121.3 0.0 6.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS81949.1 - 2.4e-27 96.0 0.0 3.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 RUS81949.1 - 0.0014 18.1 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 RUS81949.1 - 0.053 13.2 0.0 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein 7tm_1 PF00001.21 RUS81950.1 - 6.8e-10 38.7 20.3 8.3e-10 38.4 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS81950.1 - 2.7e-06 26.9 26.1 0.00013 21.4 26.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS81950.1 - 5.9e-06 26.1 24.0 8.5e-06 25.6 24.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Melibiase_2 PF16499.5 RUS81951.1 - 2.1e-143 476.6 2.1 2.6e-143 476.4 2.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 RUS81951.1 - 1.6e-09 37.8 0.0 3.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 RUS81951.1 - 4.2e-07 29.9 0.0 9.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 RUS81951.1 - 0.0022 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase F-box PF00646.33 RUS81951.1 - 0.0022 17.8 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 RUS81952.1 - 3.6e-83 279.9 0.7 3.6e-83 279.9 0.7 1.9 2 1 0 2 2 2 1 Cytochrome P450 Trypsin_2 PF13365.6 RUS81953.1 - 2.6e-06 28.4 0.0 4.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain ssDBP PF17878.1 RUS81953.1 - 0.072 13.3 2.4 0.15 12.3 0.9 2.2 3 0 0 3 3 3 0 Single-stranded DNA-binding protein WD40 PF00400.32 RUS81954.1 - 2e-49 164.5 33.2 4.5e-07 30.5 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat HHH_3 PF12836.7 RUS81954.1 - 2.4e-17 62.9 0.0 4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif Nup160 PF11715.8 RUS81954.1 - 4e-14 52.2 14.8 0.2 10.3 0.1 7.2 3 2 4 7 7 7 6 Nucleoporin Nup120/160 F-box-like PF12937.7 RUS81954.1 - 6.3e-13 48.4 1.6 1.2e-12 47.5 1.6 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 RUS81954.1 - 3.6e-12 46.4 5.4 0.15 12.3 0.1 6.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 RUS81954.1 - 4.7e-08 32.7 0.5 9.7e-08 31.7 0.5 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 RUS81954.1 - 3.1e-07 30.2 4.0 2.2e-06 27.4 4.0 2.8 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 RUS81954.1 - 0.00069 18.7 9.6 0.63 8.9 0.3 4.7 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HHH PF00633.23 RUS81954.1 - 0.027 14.4 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif PALB2_WD40 PF16756.5 RUS81954.1 - 0.043 12.7 10.2 0.61 9.0 0.2 4.9 1 1 4 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Anillin_N PF16018.5 RUS81954.1 - 0.12 13.0 0.4 5 7.8 0.0 2.6 2 0 0 2 2 2 0 Anillin N-terminus PQQ PF01011.21 RUS81954.1 - 0.17 11.9 0.2 71 3.6 0.0 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat CDtoxinA PF03498.14 RUS81954.1 - 0.22 11.1 1.8 1.3 8.5 0.2 3.0 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain Hira PF07569.11 RUS81954.1 - 0.26 11.0 7.8 9.7 5.8 0.0 5.4 2 1 5 7 7 7 0 TUP1-like enhancer of split fn3 PF00041.21 RUS81956.1 - 0.029 14.7 0.2 0.029 14.7 0.2 12.9 12 0 0 12 12 12 0 Fibronectin type III domain CDC45 PF02724.14 RUS81956.1 - 1.1 7.4 17.3 1.8 6.7 17.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS81956.1 - 5.1 5.2 25.9 7.2 4.7 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family Big_9 PF17963.1 RUS81957.1 - 3.9 8.3 5.1 1.9e+02 2.9 5.2 2.6 1 1 0 1 1 1 0 Bacterial Ig domain Pkinase_Tyr PF07714.17 RUS81958.1 - 3.5e-51 174.0 0.8 1.3e-48 165.5 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Furin-like PF00757.20 RUS81958.1 - 4.2e-35 120.8 127.5 2.5e-25 89.1 33.7 5.6 2 1 3 5 5 5 5 Furin-like cysteine rich region GF_recep_IV PF14843.6 RUS81958.1 - 3.1e-30 104.7 124.6 1.8e-17 63.4 34.3 5.6 2 2 3 5 5 5 4 Growth factor receptor domain IV Pkinase PF00069.25 RUS81958.1 - 3.6e-23 82.3 0.2 4.6e-21 75.4 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Recep_L_domain PF01030.24 RUS81958.1 - 1.9e-21 76.3 3.1 6.5e-13 48.8 0.0 2.9 2 1 0 2 2 2 2 Receptor L domain Kinase-like PF14531.6 RUS81958.1 - 2.3e-06 27.2 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Protocadherin PF08374.11 RUS81958.1 - 0.00033 20.7 0.5 0.00087 19.3 0.2 1.8 1 1 1 2 2 2 1 Protocadherin APH PF01636.23 RUS81958.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sigma_reg_N PF13800.6 RUS81958.1 - 0.12 12.7 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Atrophin-1 PF03154.15 RUS81958.1 - 0.21 9.8 3.3 0.3 9.3 3.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family FAM27 PF15832.5 RUS81958.1 - 1.5 9.4 5.3 3.7 8.2 5.3 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family PCI PF01399.27 RUS81960.1 - 5.3e-14 52.6 0.5 5.3e-14 52.6 0.5 3.8 4 0 0 4 4 4 1 PCI domain Spore_GerAC PF05504.11 RUS81961.1 - 0.00029 21.1 6.5 0.04 14.2 6.5 2.2 1 1 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal DUF1876 PF08962.11 RUS81961.1 - 0.0041 17.1 0.1 0.79 9.7 0.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF1876) Toast_rack_N PF17115.5 RUS81961.1 - 0.0082 16.4 4.9 0.21 11.9 1.3 2.2 1 1 1 2 2 2 2 N-terminal domain of toast_rack, DUF2154 AHSA1 PF08327.11 RUS81961.1 - 0.035 14.4 0.5 0.47 10.7 0.5 2.1 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein PCC_BT PF18140.1 RUS81961.1 - 0.037 14.4 2.6 0.37 11.1 2.6 2.1 1 1 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain DUF3828 PF12883.7 RUS81961.1 - 0.043 14.2 4.9 1.5 9.2 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3828) Cna_B PF05738.13 RUS81961.1 - 0.073 13.6 3.5 21 5.7 3.5 2.9 1 1 0 1 1 1 0 Cna protein B-type domain Reo_sigmaC PF04582.12 RUS81961.1 - 0.19 12.0 0.0 1.5 9.1 0.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain FAS_meander PF17951.1 RUS81961.1 - 0.2 11.4 1.7 0.84 9.4 1.2 1.9 1 1 1 2 2 2 0 Fatty acid synthase meander beta sheet domain DUF3883 PF13020.6 RUS81961.1 - 1.2 9.3 9.8 6.1 7.0 1.8 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) PhzC-PhzF PF02567.16 RUS81961.1 - 1.5 8.2 4.3 16 4.8 0.9 2.3 1 1 2 3 3 3 0 Phenazine biosynthesis-like protein cwf21 PF08312.12 RUS81961.1 - 1.8 8.8 12.8 49 4.2 0.4 5.0 6 0 0 6 6 6 0 cwf21 domain HCO3_cotransp PF00955.21 RUS81962.1 - 1.6e-212 706.9 18.8 5.1e-212 705.2 18.8 1.7 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RUS81962.1 - 1.2e-77 261.3 0.4 1.2e-77 261.3 0.4 2.8 2 1 0 2 2 2 1 Band 3 cytoplasmic domain PHD_2 PF13831.6 RUS81963.1 - 0.0017 17.8 0.6 0.0033 16.9 0.6 1.5 1 0 0 1 1 1 1 PHD-finger Zip PF02535.22 RUS81964.1 - 5.4e-35 121.2 0.4 8.9e-35 120.5 0.4 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter F-box PF00646.33 RUS81964.1 - 3.9 7.5 7.2 11 6.0 7.2 1.8 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 RUS81965.1 - 1.3e-12 47.4 0.2 2.7e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS81965.1 - 2.4e-09 36.9 2.9 3.9e-08 33.0 0.3 3.3 3 0 0 3 3 3 1 F-box domain tRNA-synt_1 PF00133.22 RUS81966.1 - 9e-17 60.5 0.0 6.1e-08 31.4 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RUS81966.1 - 1.1e-06 27.7 0.0 2.6e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) Adeno_hexon_C PF03678.14 RUS81966.1 - 0.097 12.1 0.1 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Hexon, adenovirus major coat protein, C-terminal domain TPR_1 PF00515.28 RUS81967.1 - 1.5e-43 144.9 21.5 5.8e-05 22.7 0.2 12.8 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_2 PF07719.17 RUS81967.1 - 1.4e-41 137.2 21.6 0.00017 21.5 0.0 15.1 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_8 PF13181.6 RUS81967.1 - 1.8e-36 121.3 11.9 0.0019 18.2 0.0 12.1 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.6 RUS81967.1 - 5.4e-33 113.3 5.6 9.4e-07 29.3 0.0 10.4 7 2 4 11 11 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 RUS81967.1 - 7.3e-32 107.3 14.4 0.012 16.4 0.0 13.0 10 4 4 14 14 12 8 Tetratricopeptide repeat TPR_12 PF13424.6 RUS81967.1 - 8.9e-28 96.4 18.7 2.7e-06 27.6 2.2 9.6 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 RUS81967.1 - 1.7e-24 84.4 18.5 0.1 13.0 0.1 16.8 17 1 0 17 17 17 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS81967.1 - 6.8e-23 81.0 21.5 0.00049 20.7 0.0 10.5 8 3 4 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 RUS81967.1 - 1.8e-17 62.7 16.1 2e-05 24.2 0.0 11.0 11 2 3 14 14 14 4 TPR repeat TPR_6 PF13174.6 RUS81967.1 - 6.4e-16 57.9 25.7 0.077 13.7 0.2 12.7 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS81967.1 - 7.4e-16 56.9 19.4 0.006 16.5 0.1 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 RUS81967.1 - 1.1e-14 53.7 22.1 0.0014 18.4 0.1 11.6 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 RUS81967.1 - 2.8e-07 30.6 3.3 0.04 14.1 0.0 7.0 5 2 2 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 RUS81967.1 - 9.6e-05 21.3 0.4 0.031 13.0 0.3 3.8 2 1 1 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_21 PF09976.9 RUS81967.1 - 0.00016 21.4 12.9 0.088 12.5 0.6 5.4 2 2 3 5 5 5 1 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 RUS81967.1 - 0.00026 21.2 29.8 0.12 12.7 0.2 6.8 6 2 1 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 Rapsyn_N PF10579.9 RUS81967.1 - 0.00029 20.9 2.2 7.6 6.7 0.0 5.6 4 1 1 5 5 5 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.6 RUS81967.1 - 0.0047 16.4 1.6 0.026 14.0 0.5 5.0 5 2 1 6 6 5 2 Soluble NSF attachment protein, SNAP Peptidase_S41_N PF11918.8 RUS81967.1 - 0.011 15.9 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Fis1_TPR_C PF14853.6 RUS81967.1 - 0.32 11.1 16.3 5.7 7.1 0.1 6.9 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 RUS81967.1 - 0.38 11.5 2.5 6.1e+02 1.6 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS81967.1 - 0.54 10.3 19.0 0.9 9.6 4.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF728 PF05304.12 RUS81967.1 - 3.8 7.4 7.3 21 5.0 2.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Pkinase_Tyr PF07714.17 RUS81968.1 - 3.9e-89 298.3 0.0 5.2e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS81968.1 - 4.2e-44 150.9 0.0 6.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 RUS81968.1 - 7.9e-07 29.3 0.0 0.00023 21.5 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Kinase-like PF14531.6 RUS81968.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like CarboxypepD_reg PF13620.6 RUS81968.1 - 0.0063 16.8 0.0 0.024 14.9 0.0 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4476 PF14771.6 RUS81968.1 - 0.092 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) fn3 PF00041.21 RUS81969.1 - 3.3e-10 40.2 3.2 5.5e-05 23.4 0.4 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Recep_L_domain PF01030.24 RUS81969.1 - 1.7e-09 37.8 1.4 3.9e-09 36.6 1.4 1.6 1 0 0 1 1 1 1 Receptor L domain Recep_L_domain PF01030.24 RUS81970.1 - 8.8e-20 70.9 0.0 9.9e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Receptor L domain AIG1 PF04548.16 RUS81972.1 - 4.1e-44 150.4 0.2 4.1e-44 150.4 0.2 2.2 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS81972.1 - 1.2e-06 28.5 1.1 2.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase YwqJ-deaminase PF14431.6 RUS81972.1 - 0.078 13.2 2.6 0.16 12.2 2.6 1.5 1 0 0 1 1 1 0 YwqJ-like deaminase AAA PF00004.29 RUS81972.1 - 1.1 9.7 5.6 22 5.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PA26 PF04636.13 RUS81972.1 - 1.7 7.5 8.9 2.9 6.7 8.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF724 PF05266.14 RUS81972.1 - 4.7 7.0 14.6 0.79 9.5 10.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ALMT PF11744.8 RUS81972.1 - 5.5 5.7 10.5 7.4 5.3 10.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Dynamin_N PF00350.23 RUS81972.1 - 9.9 6.2 9.4 3.7 7.6 0.4 3.2 2 1 1 3 3 3 0 Dynamin family 7tm_1 PF00001.21 RUS81973.1 - 4.5e-48 163.9 19.7 4.5e-48 163.9 19.7 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS81973.1 - 0.00066 19.5 12.9 0.00066 19.5 12.9 2.3 2 1 0 2 2 2 1 Olfactory receptor Inp1 PF12634.7 RUS81973.1 - 0.2 11.6 1.7 0.72 9.9 0.4 2.6 2 1 0 2 2 2 0 Inheritance of peroxisomes protein 1 Srg PF02118.21 RUS81973.1 - 4.5 6.9 30.0 2.6 7.7 21.9 3.1 2 1 1 3 3 3 0 Srg family chemoreceptor DUF4381 PF14316.6 RUS81974.1 - 0.11 12.8 0.9 0.15 12.3 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.10 RUS81974.1 - 0.2 11.4 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TAD2 PF18521.1 RUS81975.1 - 0.00028 20.7 21.1 2.8 8.1 0.2 7.9 3 2 7 10 10 10 1 Transactivation domain 2 VQ PF05678.14 RUS81975.1 - 0.00039 19.8 0.0 1.3e+02 2.2 0.0 7.7 10 0 0 10 10 10 0 VQ motif DUF445 PF04286.12 RUS81975.1 - 0.00055 19.8 2.8 0.0007 19.5 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) FliG_N PF14842.6 RUS81975.1 - 0.00062 20.3 2.4 0.17 12.5 0.2 2.5 1 1 1 2 2 2 2 FliG N-terminal domain Sec15 PF04091.12 RUS81975.1 - 0.0011 18.5 9.8 0.12 11.8 3.5 2.2 1 1 1 2 2 2 2 Exocyst complex subunit Sec15-like SnoaL_2 PF12680.7 RUS81975.1 - 0.0015 19.2 4.5 3.9 8.2 1.2 4.3 2 2 0 2 2 2 1 SnoaL-like domain DUF3725 PF12523.8 RUS81975.1 - 0.0016 18.7 2.0 4.4 7.7 0.1 4.7 1 1 0 2 2 2 1 Protein of unknown function (DUF3725) Arg_decarbox_C PF17944.1 RUS81975.1 - 0.004 17.7 0.4 4.3 8.0 0.0 3.5 2 2 1 3 3 3 1 Arginine decarboxylase C-terminal helical extension T4_Rnl2_C PF18043.1 RUS81975.1 - 0.005 17.0 8.1 2.5 8.3 0.5 3.9 2 2 0 2 2 2 2 T4 RNA ligase 2 C-terminal DUF3510 PF12022.8 RUS81975.1 - 0.0055 17.1 5.9 0.97 9.8 1.7 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF3510) VPR PF00522.18 RUS81975.1 - 0.011 15.7 6.2 0.12 12.4 1.0 2.6 1 1 0 2 2 2 0 VPR/VPX protein MgtE_N PF03448.17 RUS81975.1 - 0.024 15.2 0.7 4.8 7.8 0.0 2.5 1 1 1 2 2 2 0 MgtE intracellular N domain U3snoRNP10 PF12397.8 RUS81975.1 - 0.025 14.9 3.7 0.72 10.2 1.9 3.3 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 10 DUF3828 PF12883.7 RUS81975.1 - 0.034 14.5 2.4 4.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) RGS PF00615.19 RUS81975.1 - 0.035 14.4 7.1 1.5 9.1 3.0 2.9 1 1 1 2 2 2 0 Regulator of G protein signaling domain DUF3819 PF12842.7 RUS81975.1 - 0.07 13.1 2.4 0.69 9.8 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) GlutR_dimer PF00745.20 RUS81975.1 - 0.08 13.4 2.7 2 8.9 2.7 2.6 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain GAD PF02938.14 RUS81975.1 - 0.081 13.2 1.1 4.6 7.5 0.1 3.0 2 2 0 2 2 2 0 GAD domain Anticodon_1 PF08264.13 RUS81975.1 - 0.087 12.8 3.5 0.31 11.0 3.3 2.1 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA TFCD_C PF12612.8 RUS81975.1 - 0.09 12.6 4.6 0.54 10.1 2.9 2.2 1 1 1 2 2 2 0 Tubulin folding cofactor D C terminal Antiterm PF03589.13 RUS81975.1 - 0.12 12.7 0.5 17 5.8 0.2 3.2 1 1 2 3 3 3 0 Antitermination protein Nab2 PF11517.8 RUS81975.1 - 0.16 12.3 6.4 1.5 9.2 3.0 3.3 1 1 1 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) ArAE_1_C PF11728.8 RUS81975.1 - 0.2 11.7 5.7 2.2 8.3 0.4 2.6 2 1 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain MscL PF01741.18 RUS81975.1 - 0.21 11.9 1.9 16 5.8 0.4 3.1 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF5442 PF17514.2 RUS81975.1 - 0.36 11.0 1.5 13 6.0 0.2 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5442) DUF5591 PF17884.1 RUS81975.1 - 0.58 10.0 3.2 7.2 6.5 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5591) YueH PF14166.6 RUS81975.1 - 1.2 9.1 4.3 76 3.3 0.5 3.4 2 1 1 3 3 3 0 YueH-like protein DUF1474 PF07342.11 RUS81975.1 - 1.2 9.7 13.0 8.7 6.9 1.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) Phe_ZIP PF08916.11 RUS81975.1 - 1.6 9.5 15.0 43 4.9 0.8 4.2 2 2 0 2 2 2 0 Phenylalanine zipper Herpes_UL17 PF04559.12 RUS81975.1 - 2.2 7.0 4.8 1.5 7.5 2.4 1.7 1 1 1 2 2 2 0 Herpesvirus UL17 protein Tim54 PF11711.8 RUS81976.1 - 0.0023 16.8 7.4 0.0071 15.2 7.4 1.8 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 RUS81976.1 - 0.0042 16.1 12.8 0.0086 15.1 12.8 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) V_ATPase_I PF01496.19 RUS81976.1 - 0.043 11.7 9.5 0.073 11.0 9.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TERB2 PF15101.6 RUS81976.1 - 0.52 10.3 24.7 1.9 8.5 21.7 2.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Sec62 PF03839.16 RUS81976.1 - 0.61 9.6 7.5 1.6 8.2 7.5 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_23 PF13476.6 RUS81976.1 - 0.96 9.9 14.1 1.9 8.9 13.1 2.0 2 0 0 2 2 2 0 AAA domain DUF4770 PF15994.5 RUS81976.1 - 1.1 9.5 18.2 4.5 7.5 18.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AIF_C PF14721.6 RUS81976.1 - 1.2 9.5 11.6 5.5 7.4 11.6 2.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EOS1 PF12326.8 RUS81976.1 - 1.2 9.0 4.5 3.6 7.5 4.5 1.8 1 0 0 1 1 1 0 N-glycosylation protein PRC2_HTH_1 PF18118.1 RUS81976.1 - 2.6 8.9 19.3 0.39 11.6 12.4 3.2 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Peptidase_S49_N PF08496.10 RUS81976.1 - 4.2 7.4 16.2 1.2e+02 2.7 15.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.11 RUS81976.1 - 6.4 5.1 17.1 11 4.4 17.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Coilin_N PF15862.5 RUS81976.1 - 7.4 6.4 17.3 24 4.7 17.3 1.8 1 0 0 1 1 1 0 Coilin N-terminus Connexin PF00029.19 RUS81976.1 - 7.7 6.2 12.6 20 4.8 12.6 1.7 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RUS81976.1 - 7.9 4.6 14.4 11 4.2 13.0 1.8 2 0 0 2 2 2 0 CDC45-like protein AA_permease_2 PF13520.6 RUS81977.1 - 4.6e-11 42.2 14.2 5.8e-11 41.9 14.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS81977.1 - 1.7e-05 23.6 10.5 1.8e-05 23.5 10.5 1.1 1 0 0 1 1 1 1 Amino acid permease RbsD_FucU PF05025.13 RUS81979.1 - 6.9e-40 136.6 0.0 7.7e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family LSM PF01423.22 RUS81980.1 - 2.1e-15 56.2 0.4 3.4e-15 55.5 0.4 1.4 1 0 0 1 1 1 1 LSM domain RP853 PF17542.2 RUS81980.1 - 0.048 12.8 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 APH PF01636.23 RUS81981.1 - 3.2e-14 53.4 0.0 4.5e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Ldh_2 PF02615.14 RUS81981.1 - 0.036 13.2 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase RIO1 PF01163.22 RUS81981.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2345 PF10106.9 RUS81982.1 - 0.62 9.9 3.5 4.4 7.2 1.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) S-methyl_trans PF02574.16 RUS81983.1 - 2.1e-32 113.0 0.0 2.8e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Cupin_8 PF13621.6 RUS81984.1 - 2.5e-81 273.1 0.1 5.2e-81 272.1 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain FAR1 PF03101.15 RUS81984.1 - 9.4e-08 32.7 0.3 3.2e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain JmjC PF02373.22 RUS81984.1 - 0.0046 17.4 0.1 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Glucosamine_iso PF01182.20 RUS81985.1 - 7.4e-59 199.4 0.0 8.4e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DC_STAMP PF07782.13 RUS81985.1 - 0.039 13.8 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein Glyco_hydro_47 PF01532.20 RUS81987.1 - 2.4e-109 366.3 0.0 6.7e-109 364.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF1364 PF07102.12 RUS81987.1 - 0.025 14.4 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) MFS_1 PF07690.16 RUS81988.1 - 8.2e-20 71.0 25.4 2.5e-19 69.4 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS81988.1 - 4.3e-05 22.3 22.0 0.0014 17.3 4.7 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein DUF682 PF05081.12 RUS81988.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) NAD_binding_4 PF07993.12 RUS81989.1 - 2.1e-74 250.0 0.0 2.7e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 RUS81989.1 - 1.8e-30 105.0 0.4 3.5e-30 104.1 0.4 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 RUS81989.1 - 3.3e-05 23.5 0.0 0.00014 21.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RUS81989.1 - 0.00034 19.8 0.0 0.00074 18.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RUS81989.1 - 0.0059 15.6 0.1 0.12 11.4 0.0 2.6 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 RUS81989.1 - 0.0085 15.5 0.0 0.039 13.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_4 PF02390.17 RUS81990.1 - 3.2e-59 199.3 0.0 4.1e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RUS81990.1 - 0.011 16.5 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RUS81990.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.16 RUS81991.1 - 3.1e-27 95.4 30.2 3.6e-27 95.2 30.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS81991.1 - 1.1e-25 90.4 14.2 1.5e-25 90.0 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4191 PF13829.6 RUS81991.1 - 0.08 12.3 0.0 0.08 12.3 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) SH3_2 PF07653.17 RUS81992.1 - 1.4e-22 79.1 0.1 5.2e-10 38.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RUS81992.1 - 3.5e-21 74.5 1.2 1.1e-15 56.9 0.3 2.7 3 0 0 3 3 3 2 SH3 domain SH2 PF00017.24 RUS81992.1 - 2.7e-18 65.8 0.0 6.5e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.6 RUS81992.1 - 7.9e-17 60.9 0.2 1.3e-10 41.0 0.1 2.6 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 RUS81992.1 - 0.00091 19.6 0.0 0.013 15.9 0.0 2.6 3 0 0 3 3 3 1 Helically-extended SH3 domain PCB_OB PF17092.5 RUS81992.1 - 0.067 14.0 0.1 1.3 9.8 0.1 2.2 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain SH3_10 PF17902.1 RUS81992.1 - 0.13 12.4 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 SH3 domain SIR2 PF02146.17 RUS81993.1 - 8.5e-52 175.6 0.0 1.2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Trypsin_2 PF13365.6 RUS81994.1 - 1.2e-29 104.2 0.1 4.7e-24 86.0 0.0 2.2 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 RUS81994.1 - 4.5e-07 29.9 0.5 2e-06 27.8 0.1 2.2 2 0 0 2 2 2 1 Trypsin Peptidase_S29 PF02907.15 RUS81994.1 - 0.035 13.8 0.3 0.094 12.5 0.3 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S3 PF00944.19 RUS81994.1 - 0.15 11.9 0.2 0.37 10.6 0.2 1.6 1 1 0 1 1 1 0 Alphavirus core protein DUF2076 PF09849.9 RUS81996.1 - 0.096 12.7 2.7 0.25 11.3 2.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PRT_C PF08372.10 RUS81996.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal NHL PF01436.21 RUS81997.1 - 9.7e-17 60.1 0.0 0.013 15.5 0.0 5.5 5 0 0 5 5 5 5 NHL repeat SGL PF08450.12 RUS81997.1 - 1.6e-08 34.4 0.0 0.0026 17.4 0.0 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 RUS81997.1 - 1.8e-05 24.8 0.0 0.041 13.8 0.0 3.0 3 0 0 3 3 3 2 Esterase-like activity of phytase DUF5128 PF17170.4 RUS81997.1 - 0.00017 20.8 0.4 0.37 9.9 0.0 2.5 2 1 0 2 2 2 2 6-bladed beta-propeller DUF5643 PF18705.1 RUS81997.1 - 0.0026 17.7 0.2 0.004 17.1 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5643) SdiA-regulated PF06977.11 RUS81997.1 - 0.032 13.5 0.0 5.6 6.1 0.0 2.4 2 1 0 2 2 2 0 SdiA-regulated WD40 PF00400.32 RUS81997.1 - 0.16 12.9 0.2 1.3e+02 3.6 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat HepII_C PF18675.1 RUS81997.1 - 0.17 12.0 0.3 8.3 6.6 0.0 3.1 2 2 1 3 3 3 0 Heparinase II C-terminal domain CwfJ_C_1 PF04677.15 RUS81998.1 - 2.1e-38 130.9 0.2 4.6e-38 129.8 0.1 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RUS81998.1 - 1.9e-13 51.1 0.0 3.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.28 RUS81998.1 - 0.0098 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FXMRP1_C_core PF12235.8 RUS81998.1 - 0.48 11.1 6.0 0.82 10.3 6.0 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF4471 PF14740.6 RUS81999.1 - 2.2e-75 253.8 9.8 3.3e-75 253.2 9.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 RUS81999.1 - 7.2e-27 93.4 0.0 1.3e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Latexin PF06907.12 RUS81999.1 - 0.02 14.4 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Latexin DDHD PF02862.17 RUS81999.1 - 3 7.9 6.9 2.9 8.0 5.5 1.6 2 0 0 2 2 2 0 DDHD domain RRM_1 PF00076.22 RUS82001.1 - 1e-12 47.7 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) fn3 PF00041.21 RUS82003.1 - 6.7e-26 90.5 1.1 5.4e-20 71.5 0.3 2.1 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS82003.1 - 1.6e-06 28.6 0.4 5.4e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS82003.1 - 0.00051 20.3 0.0 0.0068 16.7 0.0 2.2 2 1 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III CBM_6 PF03422.15 RUS82003.1 - 0.12 12.7 0.4 0.49 10.7 0.2 1.9 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Tissue_fac PF01108.17 RUS82003.1 - 0.19 11.6 0.3 0.51 10.2 0.2 1.9 1 1 1 2 2 2 0 Tissue factor Adhes-Ig_like PF09085.10 RUS82004.1 - 7.7e-06 26.0 19.9 12 6.1 0.2 9.2 1 1 9 10 10 10 3 Adhesion molecule, immunoglobulin-like Peptidase_C107 PF17222.3 RUS82004.1 - 4.6e-05 22.6 2.6 17 4.3 0.0 5.1 1 1 7 8 8 8 5 Viral cysteine endopeptidase C107 Cornifin PF02389.15 RUS82004.1 - 0.0015 18.7 24.2 0.1 12.8 14.3 2.2 1 1 1 2 2 2 2 Cornifin (SPRR) family NusG_add PF18298.1 RUS82004.1 - 0.016 15.4 0.2 32 4.8 0.0 4.2 1 1 4 6 6 6 0 NusG additional domain RabGGT_insert PF07711.11 RUS82005.1 - 1.8e-05 25.2 9.3 7.3 7.1 0.1 5.5 1 1 5 6 6 6 5 Rab geranylgeranyl transferase alpha-subunit, insert domain TSR PF18487.1 RUS82005.1 - 6.4e-05 23.1 7.6 39 4.6 0.0 5.8 1 1 5 6 6 6 0 Thrombospondin type 1 repeat AID PF18767.1 RUS82005.1 - 0.00011 22.2 0.0 5.4 7.1 0.0 3.3 1 1 4 5 5 5 3 Activation induced deaminase Involucrin2 PF06994.11 RUS82005.1 - 0.00076 19.5 0.0 17 5.6 0.0 3.4 1 1 4 5 5 5 1 Involucrin MANEC PF07502.14 RUS82005.1 - 0.0034 17.6 3.4 7.5 6.9 0.2 3.1 1 1 2 3 3 3 3 MANEC domain EST1 PF10374.9 RUS82005.1 - 0.058 14.0 22.8 38 4.9 0.2 5.9 1 1 5 6 6 6 0 Telomerase activating protein Est1 LPD11 PF18824.1 RUS82005.1 - 0.1 12.7 18.9 19 5.4 1.6 5.6 1 1 2 3 3 3 0 Large polyvalent protein-associated domain 11 MTS_N PF08468.11 RUS82005.1 - 0.11 12.5 8.8 78 3.3 0.1 5.0 1 1 5 6 6 6 0 Methyltransferase small domain N-terminal Phage_1_1 PF08200.11 RUS82005.1 - 1.7 9.1 14.0 71 3.9 0.1 4.9 5 1 1 6 6 6 0 Bacteriophage 1.1 Protein Methyltransf_21 PF05050.12 RUS82006.1 - 0.00084 19.4 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Hormone_recep PF00104.30 RUS82007.1 - 5.1e-19 68.7 1.0 5.1e-19 68.7 1.0 2.3 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS82007.1 - 2.4e-16 60.0 5.1 5.7e-16 58.7 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PIN_6 PF17146.4 RUS82007.1 - 0.0058 17.1 0.0 6 7.5 0.0 2.8 2 0 0 2 2 2 2 PIN domain of ribonuclease DUF2722 PF10846.8 RUS82007.1 - 0.03 13.3 8.5 0.037 13.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 RUS82007.1 - 0.064 13.3 14.5 0.079 12.9 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med19 PF10278.9 RUS82007.1 - 0.17 11.8 7.2 0.16 11.9 5.3 1.9 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Spt20 PF12090.8 RUS82007.1 - 3.6 7.1 20.1 6.8 6.2 20.1 1.4 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 RUS82007.1 - 6.7 5.4 17.8 9.5 4.9 17.8 1.2 1 0 0 1 1 1 0 Androgen receptor LytB_WW PF18342.1 RUS82008.1 - 0.0027 17.8 0.4 16 5.7 0.1 3.8 1 1 3 4 4 4 2 Endo-beta-N-acetylglucosaminidase LytB WW domain LisH_2 PF16045.5 RUS82008.1 - 0.017 14.1 6.0 79 2.4 0.0 6.6 5 3 3 8 8 8 0 LisH PGM_PMM_III PF02880.16 RUS82008.1 - 0.036 14.3 0.0 35 4.6 0.0 3.8 1 1 4 5 5 5 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4011 PF13195.6 RUS82008.1 - 0.053 13.4 2.4 14 5.5 0.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF4011) zf-RRN7 PF11781.8 RUS82008.1 - 0.24 11.1 0.8 2.3e+02 1.6 0.0 4.9 2 2 6 9 9 9 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HEPN_AbiA_CTD PF18732.1 RUS82008.1 - 0.28 11.1 8.8 20 5.2 0.2 4.2 1 1 2 3 3 3 0 HEPN like, Abia C-terminal domain Methyltransf_33 PF10017.9 RUS82008.1 - 6.7 5.8 17.1 18 4.3 0.3 4.9 1 1 4 5 5 5 0 Histidine-specific methyltransferase, SAM-dependent DUF2052 PF09747.9 RUS82009.1 - 6.9e-06 26.3 24.2 1.5 8.9 0.0 2.6 1 1 1 2 2 2 1 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 RUS82009.1 - 8.2e-05 22.2 41.6 0.0022 17.5 0.0 2.5 1 1 1 2 2 2 1 SDA1 SUR7 PF06687.12 RUS82009.1 - 0.00056 19.6 1.2 0.00056 19.6 1.2 2.2 2 0 0 2 2 2 1 SUR7/PalI family YL1 PF05764.13 RUS82009.1 - 0.00094 19.4 36.0 0.00094 19.4 36.0 2.6 3 0 0 3 3 2 1 YL1 nuclear protein EphA2_TM PF14575.6 RUS82009.1 - 0.0042 17.9 0.7 0.0042 17.9 0.7 5.9 2 2 1 3 3 1 1 Ephrin type-A receptor 2 transmembrane domain CENP-B_dimeris PF09026.10 RUS82009.1 - 0.016 15.6 14.6 0.016 15.6 14.6 4.1 4 0 0 4 4 4 0 Centromere protein B dimerisation domain RR_TM4-6 PF06459.12 RUS82009.1 - 0.039 13.8 36.7 0.12 12.2 35.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AF-4 PF05110.13 RUS82009.1 - 0.12 10.5 36.4 0.14 10.3 36.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4776 PF16003.5 RUS82009.1 - 0.34 9.8 36.3 0.51 9.3 36.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF2828 PF11443.8 RUS82009.1 - 0.69 7.9 27.7 0.98 7.4 27.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SOBP PF15279.6 RUS82009.1 - 0.8 10.3 22.8 1 9.9 22.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PMSI1 PF15322.6 RUS82009.1 - 1.3 8.4 13.4 2 7.8 13.4 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Nop53 PF07767.11 RUS82009.1 - 1.4 8.2 54.5 0.18 11.2 42.9 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Paramyxo_ncap PF00973.19 RUS82009.1 - 2.4 7.0 19.3 4.3 6.1 19.3 1.5 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dsh_C PF12316.8 RUS82009.1 - 2.5 8.4 10.1 3.9 7.8 10.1 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Dapper PF15268.6 RUS82009.1 - 4.3 6.1 30.4 5.2 5.8 30.4 1.0 1 0 0 1 1 1 0 Dapper MDM10 PF12519.8 RUS82009.1 - 7.7 5.2 25.6 11 4.8 25.6 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Ribosomal_S3_C PF00189.20 RUS82012.1 - 4.9e-24 84.7 0.4 1.5e-23 83.1 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 RUS82012.1 - 2.1e-11 43.5 0.1 3.5e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 KH domain Ank_2 PF12796.7 RUS82013.1 - 1.2e-13 51.4 0.1 1.3e-10 41.8 0.0 3.6 3 1 2 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS82013.1 - 1.5e-11 44.5 0.3 0.0011 19.5 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS82013.1 - 2e-11 43.9 0.6 8.2e-05 22.8 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS82013.1 - 1.2e-10 40.7 2.5 0.0018 18.6 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 RUS82013.1 - 1.5e-09 37.8 2.8 0.00036 20.9 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeat SOCS_box PF07525.16 RUS82013.1 - 9e-06 26.0 1.2 2.7e-05 24.4 1.2 1.9 1 0 0 1 1 1 1 SOCS box WD40_like PF17005.5 RUS82014.1 - 0.00014 21.3 0.0 0.15 11.3 0.0 2.6 2 0 0 2 2 2 2 WD40-like domain Arfaptin PF06456.13 RUS82014.1 - 0.028 14.0 0.0 0.074 12.6 0.0 1.6 1 1 0 1 1 1 0 Arfaptin-like domain BBS2_Mid PF14783.6 RUS82014.1 - 0.15 12.1 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Myosin_head PF00063.21 RUS82016.1 - 1.6e-240 799.9 0.5 1.6e-240 799.9 0.5 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 RUS82016.1 - 7.9e-43 144.4 1.3 7.9e-42 141.2 0.3 2.9 2 0 0 2 2 2 1 Myosin VI cargo binding domain Myosin_N PF02736.19 RUS82016.1 - 2.4e-05 24.1 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 RUS82016.1 - 0.0074 16.7 0.0 0.0074 16.7 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS82016.1 - 0.87 9.9 0.0 0.87 9.9 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF948 PF06103.11 RUS82016.1 - 1.3 9.3 3.3 4.1 7.7 3.3 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5401 PF17380.2 RUS82016.1 - 5.4 5.0 48.2 8.2 4.4 48.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Asp-B-Hydro_N PF05279.11 RUS82016.1 - 7.7 6.5 30.5 16 5.4 30.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Thiolase_N PF00108.23 RUS82017.1 - 1.2e-97 326.4 0.3 1.7e-97 325.8 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS82017.1 - 2.2e-50 169.4 1.5 3.1e-50 168.9 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 RUS82017.1 - 0.0024 18.0 0.6 0.0074 16.4 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 RUS82017.1 - 0.014 15.2 2.0 2.2 8.2 0.3 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 RUS82017.1 - 0.015 14.8 1.7 0.015 14.8 1.7 2.6 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain LRR_8 PF13855.6 RUS82018.1 - 1.5e-27 95.1 51.5 2.4e-09 36.8 1.6 9.5 8 3 0 8 8 8 6 Leucine rich repeat TIR_2 PF13676.6 RUS82018.1 - 1.4e-13 51.4 0.0 3.9e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 RUS82018.1 - 7.4e-13 48.5 70.4 2.6e-05 24.5 1.7 13.6 7 6 7 15 15 15 7 Leucine Rich repeats (2 copies) TIR PF01582.20 RUS82018.1 - 6.8e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 RUS82018.1 - 2.3e-05 24.3 4.7 0.75 9.8 2.9 5.1 4 1 1 5 5 5 2 BspA type Leucine rich repeat region (6 copies) Fmp27_SW PF10305.9 RUS82018.1 - 0.0091 16.7 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain LRR_9 PF14580.6 RUS82018.1 - 0.042 13.3 9.1 1.7 8.1 0.7 4.1 4 1 1 5 5 5 0 Leucine-rich repeat Fer2_4 PF13510.6 RUS82018.1 - 0.069 13.2 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain C2 PF00168.30 RUS82019.1 - 2.1e-58 195.0 0.2 8.1e-31 106.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain TMEM52 PF14979.6 RUS82019.1 - 1.1e-06 28.7 2.0 2.2e-06 27.7 2.0 1.4 1 0 0 1 1 1 1 Transmembrane 52 CEP76-C2 PF15627.6 RUS82019.1 - 3.7e-05 23.3 0.0 0.16 11.5 0.0 2.5 1 1 1 2 2 2 2 CEP76 C2 domain TMEM154 PF15102.6 RUS82019.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Prominin PF05478.11 RUS82019.1 - 0.029 12.3 0.2 0.042 11.8 0.2 1.1 1 0 0 1 1 1 0 Prominin DUF4982 PF16355.5 RUS82019.1 - 0.03 14.3 0.1 0.4 10.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4982) Transglut_C PF00927.22 RUS82019.1 - 0.037 14.2 0.6 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Cadherin_C_2 PF16492.5 RUS82019.1 - 0.039 14.7 0.0 0.094 13.5 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 RUS82019.1 - 0.06 14.2 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTEN_C2 PF10409.9 RUS82019.1 - 0.086 12.6 1.5 7.4 6.3 0.0 3.1 2 1 1 3 3 3 0 C2 domain of PTEN tumour-suppressor protein TMIE PF16038.5 RUS82019.1 - 0.097 12.5 5.0 0.074 12.9 2.5 2.0 2 0 0 2 2 2 0 TMIE protein DUF997 PF06196.12 RUS82019.1 - 0.13 12.2 0.2 0.25 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Tweety PF04906.13 RUS82019.1 - 0.14 10.8 0.9 0.21 10.2 0.9 1.2 1 0 0 1 1 1 0 Tweety Lipocalin_2 PF08212.12 RUS82022.1 - 1.9e-16 60.3 0.0 2.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS82022.1 - 3.2e-12 46.9 0.0 3.9e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family 7tm_1 PF00001.21 RUS82023.1 - 0.00047 19.6 3.2 0.0006 19.2 3.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS82023.1 - 0.014 15.0 5.6 0.027 14.1 5.6 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Lipocalin_2 PF08212.12 RUS82024.1 - 3.6e-16 59.4 0.0 4.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS82024.1 - 5.5e-11 42.9 0.0 6.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 RUS82025.1 - 2e-07 31.0 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS82026.1 - 8.4e-07 29.3 0.0 9.8e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 RUS82026.1 - 0.0015 18.5 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 RUS82026.1 - 0.03 14.2 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Triabin HTH_Tnp_Tc3_2 PF01498.18 RUS82027.1 - 0.00013 22.1 0.1 0.0002 21.6 0.1 1.3 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS82027.1 - 0.0067 16.4 0.3 0.019 14.9 0.1 1.7 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF977) HTH_26 PF13443.6 RUS82027.1 - 0.13 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain C2 PF00168.30 RUS82028.1 - 6.2e-52 174.2 0.2 6.9e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 C2 domain ArfGap PF01412.18 RUS82029.1 - 3.4e-31 107.7 0.4 3.4e-31 107.7 0.4 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SVIP PF15811.5 RUS82030.1 - 2.5e-25 88.7 10.1 2.7e-25 88.6 10.1 1.0 1 0 0 1 1 1 1 Small VCP/p97-interacting protein IMUP PF15761.5 RUS82030.1 - 0.0046 17.6 1.1 0.0057 17.3 1.1 1.1 1 0 0 1 1 1 1 Immortalisation up-regulated protein U79_P34 PF03064.16 RUS82030.1 - 0.55 9.5 6.1 0.63 9.4 6.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TTL PF03133.15 RUS82032.1 - 3.6e-86 288.9 0.5 3.6e-86 288.9 0.5 1.8 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 RUS82032.1 - 4.3e-06 26.2 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 RUS82032.1 - 1.5e-05 24.4 0.0 0.015 14.6 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 RUS82032.1 - 0.0044 17.1 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain LAMTOR PF15454.6 RUS82032.1 - 0.31 11.7 5.9 3.7 8.2 5.9 2.7 1 1 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PHD PF00628.29 RUS82034.1 - 1.9e-08 34.1 7.4 3e-08 33.4 7.4 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RUS82034.1 - 0.0031 17.4 1.9 0.0031 17.4 1.9 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_2 PF03107.16 RUS82034.1 - 0.014 15.7 2.2 0.035 14.4 0.6 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 RUS82034.1 - 0.16 12.3 7.3 0.37 11.2 7.3 1.6 1 1 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 RUS82034.1 - 0.35 10.5 11.1 0.052 13.1 4.3 2.7 1 1 1 2 2 2 0 PHD-finger zf-RING_11 PF17123.5 RUS82034.1 - 0.68 9.7 6.5 1.4 8.7 6.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C4H2 PF10146.9 RUS82034.1 - 2.4 8.4 5.9 3.4 7.9 5.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein zf-PHD-like PF15446.6 RUS82034.1 - 3.9 7.1 7.4 0.73 9.4 3.7 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain YTH PF04146.15 RUS82035.1 - 9.3e-34 116.8 1.0 9.3e-34 116.8 1.0 3.4 3 1 0 3 3 2 1 YT521-B-like domain HA2 PF04408.23 RUS82035.1 - 1.8e-19 70.0 0.0 1.8e-19 70.0 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RUS82035.1 - 8.3e-16 58.3 0.0 2.6e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 RUS82035.1 - 1.7e-10 41.1 0.3 2.6e-09 37.3 0.1 3.1 2 1 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 RUS82035.1 - 5.5e-10 39.3 0.3 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ank_2 PF12796.7 RUS82035.1 - 2.9e-08 34.2 0.0 6.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) R3H PF01424.22 RUS82035.1 - 7.2e-07 29.1 0.0 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 R3H domain Ank_5 PF13857.6 RUS82035.1 - 7.5e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_19 PF13245.6 RUS82035.1 - 0.00025 21.4 0.0 0.00062 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 RUS82035.1 - 0.0012 19.4 0.0 0.073 13.7 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) FtsK_SpoIIIE PF01580.18 RUS82035.1 - 0.0038 16.6 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family SRP54 PF00448.22 RUS82035.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 RUS82035.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 RUS82035.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Ank_3 PF13606.6 RUS82035.1 - 0.079 13.5 0.0 0.32 11.7 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat AAA_22 PF13401.6 RUS82035.1 - 0.1 12.9 0.1 0.64 10.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS82035.1 - 0.13 12.0 0.1 0.47 10.2 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fez1 PF06818.15 RUS82036.1 - 0.00048 20.6 20.9 0.00048 20.6 20.9 3.0 1 1 1 3 3 3 1 Fez1 NPV_P10 PF05531.12 RUS82036.1 - 0.00073 20.0 17.3 0.85 10.1 0.1 4.7 4 2 0 4 4 4 3 Nucleopolyhedrovirus P10 protein GAS PF13851.6 RUS82036.1 - 0.0031 16.9 46.9 0.0086 15.5 11.7 3.2 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding APS_kinase PF01583.20 RUS82036.1 - 0.0084 16.0 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase HMMR_N PF15905.5 RUS82036.1 - 0.022 14.2 41.6 0.26 10.7 10.8 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 RUS82036.1 - 0.024 13.5 44.1 0.084 11.7 16.3 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 RUS82036.1 - 0.033 14.3 42.8 0.12 12.5 15.3 3.7 2 1 1 3 3 3 0 Tropomyosin like CENP-H PF05837.12 RUS82036.1 - 0.043 14.2 40.2 0.07 13.5 8.7 4.1 1 1 2 4 4 4 0 Centromere protein H (CENP-H) Pox_A_type_inc PF04508.12 RUS82036.1 - 0.16 11.9 0.3 0.16 11.9 0.3 4.5 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat CREPT PF16566.5 RUS82036.1 - 0.39 10.9 29.2 6.6 6.9 13.6 3.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TMF_TATA_bd PF12325.8 RUS82036.1 - 0.91 9.8 43.2 1.7 8.9 2.1 4.1 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Phage_pRha PF09669.10 RUS82036.1 - 2.1 9.0 10.4 0.91 10.1 0.8 2.9 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Fib_alpha PF08702.10 RUS82036.1 - 3.4 7.8 32.4 8.8 6.5 8.8 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family OEP PF02321.18 RUS82036.1 - 7.2 6.4 19.5 3.8 7.3 2.2 3.5 2 1 1 3 3 3 0 Outer membrane efflux protein DUF2203 PF09969.9 RUS82036.1 - 8 7.2 22.8 2.9 8.7 0.3 3.8 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF1647 PF07801.11 RUS82038.1 - 9.5e-13 48.1 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) CKS PF01111.19 RUS82039.1 - 1.3e-28 99.1 8.0 5.3e-24 84.3 1.0 2.2 2 0 0 2 2 2 2 Cyclin-dependent kinase regulatory subunit BAR PF03114.18 RUS82040.1 - 2.4e-72 243.5 7.9 2.9e-72 243.2 7.9 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 RUS82040.1 - 1.2e-15 57.4 5.0 4.3e-13 49.1 2.9 2.2 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_9 PF14604.6 RUS82040.1 - 2.3e-13 49.7 0.4 4.1e-13 49.0 0.4 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS82040.1 - 1.1e-10 41.0 0.1 1.9e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS82040.1 - 1.8e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 RUS82040.1 - 0.0002 21.1 6.9 0.00042 20.1 6.0 2.0 1 1 0 1 1 1 1 BAR domain of APPL family P4Ha_N PF08336.11 RUS82040.1 - 0.048 13.7 0.6 0.048 13.7 0.6 2.0 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4890 PF16231.5 RUS82040.1 - 3.6 8.1 7.7 0.71 10.4 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) zf-C3HC4_2 PF13923.6 RUS82041.1 - 1.2e-08 34.6 13.3 3.1e-08 33.3 13.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82041.1 - 2.4e-07 30.5 13.7 6.3e-07 29.2 13.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 RUS82041.1 - 1.3e-05 25.8 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 RUS82041.1 - 1.8e-05 25.0 11.6 1.8e-05 25.0 11.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RUS82041.1 - 0.00032 20.6 13.2 0.0014 18.5 13.3 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS82041.1 - 0.0028 17.5 12.5 0.0028 17.5 12.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS82041.1 - 0.0029 17.9 9.5 0.0098 16.2 9.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS82041.1 - 0.0036 17.3 9.6 0.0036 17.3 9.6 2.4 2 1 0 2 2 2 1 RING-type zinc-finger APG12 PF04110.13 RUS82041.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Glyco_hydro_36C PF16874.5 RUS82041.1 - 0.044 14.3 0.0 9.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain Prok-RING_4 PF14447.6 RUS82041.1 - 0.051 13.4 14.8 0.28 11.1 13.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad60-SLD PF11976.8 RUS82041.1 - 0.18 11.6 0.2 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-RING_6 PF14835.6 RUS82041.1 - 0.22 11.4 4.6 0.49 10.3 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 RUS82041.1 - 0.32 10.9 8.7 0.68 9.8 7.4 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 RUS82041.1 - 2.8 8.2 18.0 0.49 10.6 13.6 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TB2_DP1_HVA22 PF03134.19 RUS82043.1 - 4.7e-29 100.1 9.3 4.7e-29 100.1 9.3 1.9 2 0 0 2 2 2 1 TB2/DP1, HVA22 family MT0933_antitox PF14013.6 RUS82043.1 - 0.00024 21.4 1.0 0.0012 19.0 0.2 2.2 2 0 0 2 2 2 1 MT0933-like antitoxin protein Fijivirus_P9-2 PF06837.11 RUS82043.1 - 0.094 12.2 2.3 0.067 12.6 0.5 1.6 2 0 0 2 2 2 0 Fijivirus P9-2 protein DUF4205 PF13898.6 RUS82044.1 - 5.5e-06 25.6 0.1 0.046 12.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_6 PF13405.6 RUS82044.1 - 0.00071 19.3 0.1 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 RUS82044.1 - 0.015 14.8 0.1 0.062 12.9 0.0 2.1 2 1 1 3 3 3 0 EF hand EF-hand_7 PF13499.6 RUS82044.1 - 0.076 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair DUF4205 PF13898.6 RUS82045.1 - 2.4e-33 115.5 0.2 1.6e-32 112.8 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) DUF1115 PF06544.12 RUS82045.1 - 0.019 15.1 0.2 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Thioredoxin PF00085.20 RUS82046.1 - 9e-67 221.6 1.8 2.6e-33 114.1 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 RUS82046.1 - 2.1e-28 99.5 1.2 1.5e-23 83.7 0.3 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RUS82046.1 - 2.3e-09 37.6 3.7 0.0019 18.6 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS82046.1 - 3.1e-07 30.6 0.0 0.041 14.2 0.0 3.9 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RUS82046.1 - 5.2e-07 29.6 0.0 0.039 13.9 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 RUS82046.1 - 1.8e-06 28.1 0.0 0.073 13.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 RUS82046.1 - 1.2e-05 25.1 0.1 0.04 13.6 0.0 2.7 2 0 0 2 2 2 2 Redoxin OST3_OST6 PF04756.13 RUS82046.1 - 6.9e-05 22.3 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 RUS82046.1 - 0.012 15.8 1.0 2.7 8.1 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin TraF PF13728.6 RUS82046.1 - 0.15 11.9 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein GnsAB_toxin PF08178.11 RUS82046.1 - 0.26 11.2 2.8 4.1 7.4 0.0 3.1 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Tim54 PF11711.8 RUS82047.1 - 0.001 17.9 9.3 0.001 17.9 9.3 1.7 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 RUS82047.1 - 0.0028 17.2 14.2 0.0028 17.2 14.2 1.6 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 RUS82047.1 - 0.0066 16.7 6.8 0.0066 16.7 6.8 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 RUS82047.1 - 0.007 16.3 1.4 0.007 16.3 1.4 2.0 2 0 0 2 2 2 1 N-glycosylation protein DUF2207 PF09972.9 RUS82047.1 - 0.0071 15.2 1.6 0.0087 14.9 1.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PEHE PF15275.6 RUS82047.1 - 0.0094 16.6 1.9 0.0094 16.6 1.9 2.1 2 0 0 2 2 2 1 PEHE domain Peroxin-13_N PF04088.13 RUS82047.1 - 0.0098 16.2 5.4 0.0098 16.2 5.4 1.7 2 0 0 2 2 2 1 Peroxin 13, N-terminal region MDM10 PF12519.8 RUS82047.1 - 0.03 13.2 5.4 0.037 12.9 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RNA_pol_Rpc4 PF05132.14 RUS82047.1 - 0.04 14.3 17.8 0.038 14.4 15.0 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 ASC PF00858.24 RUS82047.1 - 0.057 12.4 0.5 0.063 12.2 0.5 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DcuA_DcuB PF03605.14 RUS82047.1 - 0.12 11.2 1.3 0.17 10.7 1.3 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter LIM_bind PF01803.16 RUS82047.1 - 0.22 11.0 7.5 0.41 10.1 7.5 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Pap_E4 PF02711.14 RUS82047.1 - 0.25 12.3 17.0 0.17 12.9 4.5 2.3 2 0 0 2 2 2 0 E4 protein Presenilin PF01080.17 RUS82047.1 - 0.36 9.5 12.8 0.59 8.8 12.8 1.3 1 1 0 1 1 1 0 Presenilin DUF913 PF06025.12 RUS82047.1 - 0.41 9.6 5.1 0.057 12.4 1.5 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) VKG_Carbox PF05090.14 RUS82047.1 - 0.44 9.3 2.7 0.61 8.9 2.7 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Vfa1 PF08432.10 RUS82047.1 - 0.47 10.8 31.9 0.033 14.5 25.5 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DAG_kinase_N PF14513.6 RUS82047.1 - 0.47 10.7 12.6 0.089 13.0 7.7 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RR_TM4-6 PF06459.12 RUS82047.1 - 0.89 9.3 24.3 0.15 11.8 18.9 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PGA_cap PF09587.10 RUS82047.1 - 1 8.7 3.1 1.6 8.1 3.1 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap SpoVR PF04293.13 RUS82047.1 - 1 7.9 12.1 1.7 7.2 12.1 1.3 1 0 0 1 1 1 0 SpoVR like protein PRC2_HTH_1 PF18118.1 RUS82047.1 - 1.1 10.1 22.4 0.17 12.7 16.3 2.0 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Eapp_C PF10238.9 RUS82047.1 - 1.1 9.3 18.4 0.19 11.8 10.9 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein ORC_WH_C PF18137.1 RUS82047.1 - 1.2 9.3 17.0 0.88 9.6 13.0 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal BSMAP PF12280.8 RUS82047.1 - 1.2 9.3 10.2 0.22 11.7 5.9 1.8 2 0 0 2 2 2 0 Brain specific membrane anchored protein TraV PF09676.10 RUS82047.1 - 1.6 9.7 11.6 0.18 12.8 6.8 1.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) DUF2052 PF09747.9 RUS82047.1 - 2.3 8.3 17.0 2.8 8.0 12.4 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Orf78 PF06024.12 RUS82047.1 - 2.7 8.3 6.9 0.41 11.0 2.3 1.9 2 0 0 2 2 2 0 Orf78 (ac78) LicD PF04991.13 RUS82047.1 - 3.8 7.6 17.9 0.35 11.0 13.6 1.4 2 0 0 2 2 1 0 LicD family Rxt3 PF08642.10 RUS82047.1 - 4.3 8.1 11.1 1 10.1 6.3 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 RUS82047.1 - 4.6 6.9 23.1 0.33 10.7 16.6 1.9 2 0 0 2 2 2 0 Connexin Afi1 PF07792.12 RUS82047.1 - 5 7.6 17.6 0.98 9.9 11.8 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AIF_C PF14721.6 RUS82047.1 - 5.9 7.2 15.3 1.1 9.6 10.4 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CSG2 PF16965.5 RUS82047.1 - 6 5.7 5.6 0.55 9.1 1.1 1.5 2 0 0 2 2 2 0 Ceramide synthase regulator DUF789 PF05623.12 RUS82047.1 - 6.4 6.4 9.9 0.29 10.8 3.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF789) EMC3_TMCO1 PF01956.16 RUS82047.1 - 7.9 6.2 14.6 0.2 11.4 7.0 1.9 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like LRR_8 PF13855.6 RUS82048.1 - 2e-22 78.7 23.1 1.9e-12 46.7 1.5 6.1 3 1 2 6 6 6 4 Leucine rich repeat TIR PF01582.20 RUS82048.1 - 1.1e-19 70.9 0.0 2.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS82048.1 - 4.1e-15 56.4 0.0 9.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 RUS82048.1 - 1.4e-14 54.0 30.3 4.5e-06 26.9 1.3 6.8 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS82048.1 - 0.00015 21.7 1.1 0.00042 20.3 1.1 1.8 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS82048.1 - 0.00034 20.1 14.5 0.012 15.1 2.0 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RUS82048.1 - 0.0022 17.9 17.4 3.7 7.8 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich repeat DUF1863 PF08937.11 RUS82048.1 - 0.088 13.1 0.1 0.34 11.2 0.1 1.9 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Ig_3 PF13927.6 RUS82049.1 - 1.6e-20 73.5 0.8 1e-08 35.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS82049.1 - 1.1e-17 63.8 0.5 3e-07 30.4 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS82049.1 - 2.7e-15 56.3 0.0 6e-08 32.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS82049.1 - 1e-14 54.6 1.6 3.8e-05 24.0 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS82049.1 - 1.3e-12 47.9 0.2 1.8e-06 28.1 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS82049.1 - 1.1e-05 24.8 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 RUS82049.1 - 0.0063 16.9 0.4 1.3 9.4 0.0 3.5 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Herpes_gE PF02480.16 RUS82049.1 - 0.0084 14.9 0.7 0.66 8.7 0.1 2.2 1 1 0 2 2 2 2 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 RUS82049.1 - 0.0091 16.0 0.1 5.6 7.1 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 RUS82049.1 - 0.022 14.9 0.0 1.1 9.5 0.0 2.7 2 1 1 3 3 3 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 RUS82049.1 - 0.55 10.1 0.1 0.55 10.1 0.1 2.7 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 PLAC8 PF04749.17 RUS82050.1 - 6.8e-10 39.8 11.7 8.7e-10 39.5 11.7 1.2 1 0 0 1 1 1 1 PLAC8 family PHD PF00628.29 RUS82051.1 - 2.5e-09 36.9 9.7 5.4e-09 35.8 9.7 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RUS82051.1 - 7.7e-06 25.7 6.2 2.1e-05 24.3 3.2 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RUS82051.1 - 0.00051 19.9 2.6 0.00051 19.9 2.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 RUS82051.1 - 0.0015 18.1 4.8 0.0015 18.1 4.8 3.1 3 2 1 4 4 4 1 PHD/FYVE-zinc-finger like domain BUD22 PF09073.10 RUS82051.1 - 0.0018 17.7 28.5 0.0018 17.7 28.5 2.1 2 0 0 2 2 2 1 BUD22 PHD_2 PF13831.6 RUS82051.1 - 0.0087 15.6 6.8 0.0087 15.6 6.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_9 PF13901.6 RUS82051.1 - 0.0096 15.9 5.1 0.02 14.9 5.1 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 RUS82051.1 - 0.023 14.8 9.0 0.023 14.8 9.0 2.7 2 1 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 RUS82051.1 - 1.1 9.4 4.7 0.17 12.0 0.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) adh_short PF00106.25 RUS82052.1 - 1.4e-39 135.6 0.1 1.7e-39 135.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82052.1 - 7.3e-28 97.7 0.0 9.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS82052.1 - 3.8e-06 26.9 0.4 5.5e-06 26.4 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS82052.1 - 0.00039 19.9 0.1 0.0005 19.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS82052.1 - 0.0014 18.1 0.1 0.0019 17.7 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 RUS82053.1 - 1.9e-70 237.3 0.0 2.2e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82053.1 - 4.9e-28 98.1 0.0 6.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS82053.1 - 0.0064 15.5 0.0 0.021 13.8 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS82053.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RUS82053.1 - 0.08 11.9 0.1 0.19 10.6 0.2 1.6 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 RUS82053.1 - 0.16 11.3 0.0 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like PDZ PF00595.24 RUS82054.1 - 7.6e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS82054.1 - 1.9e-07 31.3 0.1 5.1e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS82054.1 - 4.5e-07 29.6 0.0 8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RUS82054.1 - 0.0099 15.8 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain SDA1 PF05285.12 RUS82055.1 - 0.037 13.5 12.1 0.046 13.2 12.1 1.2 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.11 RUS82055.1 - 0.28 10.0 2.9 0.37 9.6 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 RUS82055.1 - 0.35 9.0 14.5 0.4 8.8 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS82055.1 - 0.5 9.7 11.3 0.62 9.3 11.3 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 RUS82055.1 - 1.4 8.0 17.6 3.1 6.9 17.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RUS82055.1 - 1.9 6.7 8.3 2.4 6.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 RUS82055.1 - 2.1 8.0 15.4 3.2 7.4 15.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Fibrinogen_C PF00147.18 RUS82056.1 - 6.8e-53 179.7 5.0 1.8e-52 178.3 5.0 1.7 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain YabA PF06156.13 RUS82056.1 - 0.65 10.7 5.9 1 10.1 2.4 2.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF2730 PF10805.8 RUS82056.1 - 0.9 9.7 6.5 0.33 11.1 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) RIFIN PF02009.16 RUS82056.1 - 3.4 7.5 16.9 2.6 7.8 1.2 2.2 1 1 1 2 2 2 0 Rifin ING PF12998.7 RUS82056.1 - 8.1 7.1 7.8 22 5.7 1.2 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Pentapeptide_4 PF13599.6 RUS82058.1 - 0.0035 17.5 3.4 0.055 13.7 1.0 2.7 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) PMG PF05287.12 RUS82058.1 - 0.054 13.5 0.3 0.07 13.2 0.3 1.2 1 0 0 1 1 1 0 PMG protein Neur_chan_memb PF02932.16 RUS82059.1 - 1.5e-31 110.3 0.0 2.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS82059.1 - 1.1e-27 96.8 2.4 2.5e-25 89.2 2.5 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Pex14_N PF04695.13 RUS82059.1 - 0.033 14.8 0.4 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2417 PF10329.9 RUS82059.1 - 0.067 12.6 10.4 1.2 8.5 0.0 2.9 2 1 0 2 2 2 0 Region of unknown function (DUF2417) DUF2678 PF10856.8 RUS82061.1 - 4.3e-06 26.6 5.5 5.3e-06 26.3 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) WBP-1 PF11669.8 RUS82061.1 - 0.014 16.0 0.1 0.056 14.1 0.0 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 PIG-Y PF15159.6 RUS82061.1 - 0.17 12.8 7.1 16 6.5 6.4 2.4 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF5381 PF17353.2 RUS82061.1 - 1.1 8.9 5.8 0.19 11.5 1.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Wzy_C PF04932.15 RUS82061.1 - 1.2 8.8 4.9 2.9 7.5 4.9 1.7 1 1 0 1 1 1 0 O-Antigen ligase DUF1453 PF07301.11 RUS82062.1 - 0.008 16.2 2.1 0.011 15.7 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1453) DUF2678 PF10856.8 RUS82062.1 - 0.014 15.3 4.2 0.018 15.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Transmemb_17 PF09799.9 RUS82062.1 - 0.014 16.0 6.3 0.018 15.6 6.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein Gemini_mov PF01708.16 RUS82062.1 - 0.041 13.6 1.4 0.11 12.2 1.4 1.8 1 1 0 1 1 1 0 Geminivirus putative movement protein DUF2207 PF09972.9 RUS82062.1 - 0.26 10.0 0.6 0.32 9.7 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2892 PF11127.8 RUS82062.1 - 2 8.5 6.5 0.43 10.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) DUF805 PF05656.14 RUS82062.1 - 8 6.9 7.4 14 6.2 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Mito_carr PF00153.27 RUS82063.1 - 2.9e-70 232.2 5.8 5.5e-25 87.1 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RUS82063.1 - 0.0091 15.2 0.1 5.6 6.0 0.0 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease EF-hand_7 PF13499.6 RUS82064.1 - 5.4e-19 68.4 0.9 1.1e-08 35.4 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS82064.1 - 3.6e-17 60.6 3.9 2.9e-06 26.4 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 RUS82064.1 - 1.5e-16 58.8 2.4 5.1e-06 26.0 0.2 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RUS82064.1 - 4e-12 45.0 6.0 0.00021 20.7 0.6 4.8 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS82064.1 - 1.6e-11 43.9 3.0 3.3e-05 23.6 0.6 4.3 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS82064.1 - 0.0045 17.3 0.3 3.2 8.1 0.0 2.9 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region GH-E PF14410.6 RUS82064.1 - 0.023 15.1 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues WBP-1 PF11669.8 RUS82065.1 - 0.42 11.3 25.6 2.4 8.8 25.6 2.4 1 1 0 1 1 1 0 WW domain-binding protein 1 ResB PF05140.14 RUS82065.1 - 9.5 4.8 5.3 12 4.5 5.3 1.1 1 0 0 1 1 1 0 ResB-like family WD40 PF00400.32 RUS82066.1 - 2.1e-48 161.3 28.3 4.6e-09 36.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS82066.1 - 4e-08 33.5 1.6 0.2 12.0 0.0 4.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS82066.1 - 0.00037 19.5 0.6 6.2 5.7 0.1 3.9 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RUS82066.1 - 0.0066 15.2 9.3 0.3 9.7 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RUS82066.1 - 0.033 12.7 0.0 0.17 10.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 RUS82066.1 - 0.069 13.1 0.1 22 5.2 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Polysacc_synt_2 PF02719.15 RUS82066.1 - 0.28 10.3 0.0 0.47 9.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Metallophos PF00149.28 RUS82067.1 - 7.4e-35 121.3 0.6 1.3e-34 120.5 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS82067.1 - 0.0048 17.3 0.2 0.01 16.3 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain 23S_rRNA_IVP PF05635.11 RUS82067.1 - 0.008 16.5 0.4 0.019 15.2 0.4 1.5 1 0 0 1 1 1 1 23S rRNA-intervening sequence protein Glyco_hydro_65N PF03636.15 RUS82067.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Pyridoxal_deC PF00282.19 RUS82070.1 - 2.6e-139 464.1 0.0 3.9e-139 463.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RUS82070.1 - 1e-05 25.0 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-RING_2 PF13639.6 RUS82071.1 - 2.5e-12 46.9 9.8 5.6e-12 45.8 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS82071.1 - 9.3e-09 35.0 9.7 2.1e-08 33.9 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS82071.1 - 5.6e-07 29.7 8.1 5.6e-07 29.7 8.1 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS82071.1 - 2.1e-06 27.6 5.6 5.6e-06 26.3 5.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS82071.1 - 4.1e-06 26.6 8.1 4.1e-06 26.6 8.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82071.1 - 1.1e-05 25.2 9.1 2.3e-05 24.2 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS82071.1 - 1.4e-05 24.7 8.1 3.2e-05 23.6 8.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RUS82071.1 - 0.00015 21.6 8.4 0.00032 20.6 8.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_MLP1_2 PF07926.12 RUS82071.1 - 0.00072 19.6 31.6 0.038 14.1 3.7 3.3 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein zf-ANAPC11 PF12861.7 RUS82071.1 - 0.0019 18.2 4.9 0.0043 17.1 4.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RUS82071.1 - 0.0023 17.8 8.9 0.0023 17.8 8.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 APG6_N PF17675.1 RUS82071.1 - 0.0023 18.4 34.1 0.052 14.1 10.3 3.3 2 1 1 3 3 3 2 Apg6 coiled-coil region Filament PF00038.21 RUS82071.1 - 0.0025 17.5 26.7 0.0043 16.7 26.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein Zn_ribbon_17 PF17120.5 RUS82071.1 - 0.01 15.5 8.8 0.019 14.6 8.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Suppressor_APC PF11414.8 RUS82071.1 - 0.016 15.3 3.3 0.016 15.3 3.3 3.4 3 1 1 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein DUF5340 PF17275.2 RUS82071.1 - 0.033 14.3 1.9 1.9 8.7 0.4 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Fez1 PF06818.15 RUS82071.1 - 0.039 14.4 30.1 0.56 10.6 14.7 2.5 1 1 1 2 2 2 0 Fez1 zf-UDP PF14569.6 RUS82071.1 - 0.056 13.6 1.7 0.13 12.4 1.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 RUS82071.1 - 0.077 13.1 1.0 0.24 11.6 1.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain HisKA_3 PF07730.13 RUS82071.1 - 0.27 11.8 5.5 9.1 6.9 0.0 4.2 2 1 2 4 4 4 0 Histidine kinase Spc7 PF08317.11 RUS82071.1 - 0.27 10.1 32.4 0.21 10.4 12.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-RING_4 PF14570.6 RUS82071.1 - 0.38 10.6 5.4 0.84 9.5 5.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RUS82071.1 - 0.52 10.5 6.9 1.6 8.9 6.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain TMPIT PF07851.13 RUS82071.1 - 0.64 9.2 19.0 0.16 11.2 3.5 2.4 2 0 0 2 2 2 0 TMPIT-like protein RINGv PF12906.7 RUS82071.1 - 1.1 9.5 7.9 2.8 8.1 7.9 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 RUS82071.1 - 1.4 9.1 8.5 3.4 7.9 8.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Laminin_I PF06008.14 RUS82071.1 - 2 8.0 25.6 0.056 13.1 1.8 3.6 2 1 3 5 5 5 0 Laminin Domain I Nup88 PF10168.9 RUS82071.1 - 2.3 5.9 20.4 4.4 5.0 20.4 1.4 1 0 0 1 1 1 0 Nuclear pore component Sulfatase_C PF14707.6 RUS82071.1 - 2.9 8.6 5.7 1.2 9.9 0.1 3.2 2 2 2 4 4 2 0 C-terminal region of aryl-sulfatase zf-RING_10 PF16685.5 RUS82071.1 - 5.8 7.1 9.9 3.1 8.0 5.9 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Uso1_p115_C PF04871.13 RUS82071.1 - 9.2 6.7 29.2 8.6 6.7 12.2 3.4 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 RUS82071.1 - 9.7 6.5 31.7 3.9 7.7 12.0 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding P4Ha_N PF08336.11 RUS82072.1 - 1.8e-18 66.8 0.0 3.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PIG-P PF08510.12 RUS82072.1 - 0.14 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 PIG-P DUF4446 PF14584.6 RUS82072.1 - 0.14 12.1 0.5 0.21 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3139 PF11337.8 RUS82072.1 - 0.15 12.8 2.8 0.3 11.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF929 PF06053.11 RUS82072.1 - 0.91 8.8 3.6 1.6 8.0 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ASFV_J13L PF05568.11 RUS82072.1 - 4.2 7.1 5.6 18 5.0 6.5 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein Sigma_reg_N PF13800.6 RUS82072.1 - 4.8 7.5 7.9 9.2 6.6 7.9 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf_CCCH_5 PF18384.1 RUS82073.1 - 5.6e-19 68.0 17.5 5.6e-19 68.0 17.5 3.5 3 1 0 3 3 3 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 RUS82073.1 - 0.0054 16.6 0.3 0.0054 16.6 0.3 7.4 8 0 0 8 8 8 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS82073.1 - 0.039 14.0 0.0 0.039 14.0 0.0 5.9 5 0 0 5 5 5 0 Zinc finger domain Histone PF00125.24 RUS82074.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RUS82074.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 RUS82074.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RUS82074.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 RUS82074.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCSMST1 PF15013.6 RUS82075.1 - 3.7e-15 55.8 0.0 6.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 CCSMST1 family Ribosomal_S8 PF00410.19 RUS82076.1 - 1.4e-20 73.5 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 ABC_membrane PF00664.23 RUS82077.1 - 1.3e-70 238.2 38.1 1.2e-38 133.3 11.6 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS82077.1 - 5.5e-52 175.9 0.0 1.5e-29 103.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RUS82077.1 - 2.9e-09 36.7 4.2 0.016 14.7 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS82077.1 - 7.4e-07 29.2 0.1 0.08 13.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS82077.1 - 3.7e-06 26.6 1.2 0.0085 15.8 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS82077.1 - 8.7e-06 25.7 4.0 0.0031 17.4 0.1 3.5 4 0 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 RUS82077.1 - 1.1e-05 25.8 0.2 0.075 13.4 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 RUS82077.1 - 4.8e-05 23.3 0.1 0.21 11.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RUS82077.1 - 0.00016 22.2 0.6 0.13 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RUS82077.1 - 0.0002 21.6 0.1 0.69 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RUS82077.1 - 0.0019 17.8 0.6 0.37 10.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 RUS82077.1 - 0.0022 17.7 0.6 3 7.5 0.0 3.3 4 0 0 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.9 RUS82077.1 - 0.0077 15.2 1.8 0.75 8.6 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 RUS82077.1 - 0.0083 15.7 0.1 0.34 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 RUS82077.1 - 0.0089 15.2 0.2 6.7 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 RUS82077.1 - 0.011 15.0 0.6 2.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 RUS82077.1 - 0.015 15.4 0.7 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_ATPase PF09818.9 RUS82077.1 - 0.016 14.0 0.0 3.8 6.2 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 RUS82077.1 - 0.019 14.7 2.3 1.4 8.7 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 RUS82077.1 - 0.019 14.6 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 RUS82077.1 - 0.019 15.3 0.2 16 6.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase MeaB PF03308.16 RUS82077.1 - 0.024 13.6 0.6 0.46 9.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_PrkA PF08298.11 RUS82077.1 - 0.025 13.5 0.1 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_11 PF13086.6 RUS82077.1 - 0.067 13.0 0.1 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 RUS82077.1 - 0.07 13.7 0.3 55 4.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RUS82077.1 - 0.084 13.1 0.1 21 5.3 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_10 PF12846.7 RUS82077.1 - 0.092 11.7 0.5 3.9 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.19 RUS82077.1 - 0.11 12.0 1.0 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 RUS82077.1 - 0.19 10.9 1.2 11 5.1 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain TsaE PF02367.17 RUS82077.1 - 0.24 11.4 1.2 4.2 7.4 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 RUS82077.1 - 0.63 10.1 4.0 3.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Dynamin family RSB_motif PF16294.5 RUS82078.1 - 0.059 13.6 14.5 0.1 12.9 14.5 1.4 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Cnd2 PF05786.14 RUS82078.1 - 0.99 8.0 5.9 1.2 7.7 5.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CDC45 PF02724.14 RUS82078.1 - 1.1 7.5 8.7 1.1 7.5 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 RUS82078.1 - 2.9 7.9 5.7 4.4 7.3 5.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Circo_capsid PF02443.15 RUS82078.1 - 3 7.4 9.4 3.1 7.3 9.4 1.1 1 0 0 1 1 1 0 Circovirus capsid protein DUF2058 PF09831.9 RUS82078.1 - 6.6 6.9 8.8 12 6.0 8.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Prominin PF05478.11 RUS82079.1 - 1.3e-06 26.7 3.0 1.5e-06 26.5 3.0 1.0 1 0 0 1 1 1 1 Prominin Prominin PF05478.11 RUS82080.1 - 2.6e-105 353.1 9.5 2.9e-105 353.0 9.5 1.0 1 0 0 1 1 1 1 Prominin DUF2207 PF09972.9 RUS82080.1 - 0.00049 19.0 0.0 0.00049 19.0 0.0 2.3 2 1 1 3 3 3 1 Predicted membrane protein (DUF2207) LMBR1 PF04791.16 RUS82080.1 - 0.00099 18.1 8.3 0.0033 16.4 0.1 3.0 3 0 0 3 3 3 1 LMBR1-like membrane protein DUF883 PF05957.13 RUS82080.1 - 0.0081 16.7 6.6 0.35 11.5 2.7 3.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) EzrA PF06160.12 RUS82080.1 - 0.02 13.1 31.3 0.49 8.5 8.9 3.4 2 2 0 3 3 3 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 RUS82080.1 - 0.05 14.0 0.3 0.05 14.0 0.3 6.1 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Apolipoprotein PF01442.18 RUS82080.1 - 0.09 12.6 19.5 0.089 12.7 7.2 3.7 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain EI24 PF07264.11 RUS82080.1 - 0.093 13.0 0.2 0.2 11.9 0.1 1.5 2 0 0 2 2 1 0 Etoposide-induced protein 2.4 (EI24) Presenilin PF01080.17 RUS82080.1 - 0.17 10.6 4.2 3.6 6.3 0.7 2.5 2 0 0 2 2 2 0 Presenilin SMBP PF16785.5 RUS82080.1 - 0.19 12.0 3.8 0.63 10.3 3.8 1.9 1 0 0 1 1 1 0 Small metal-binding protein HisKA_3 PF07730.13 RUS82080.1 - 0.3 11.6 5.5 2.2 8.8 0.8 3.4 2 1 1 3 3 3 0 Histidine kinase DUF2970 PF11174.8 RUS82080.1 - 0.44 10.4 2.5 27 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1664 PF07889.12 RUS82080.1 - 0.66 10.0 20.7 0.42 10.7 2.3 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) MCU PF04678.13 RUS82080.1 - 0.67 10.0 10.9 0.23 11.6 0.4 3.2 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Val_tRNA-synt_C PF10458.9 RUS82080.1 - 2.3 8.6 11.8 1.2 9.4 2.6 3.7 3 1 1 4 4 3 0 Valyl tRNA synthetase tRNA binding arm DUF1218 PF06749.12 RUS82080.1 - 3.1 8.4 6.9 9.2 6.9 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Exonuc_VII_L PF02601.15 RUS82080.1 - 6 6.3 16.2 4.2 6.8 7.7 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit KfrA_N PF11740.8 RUS82080.1 - 8 7.2 9.1 7.4 7.3 3.7 3.0 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Robl_LC7 PF03259.17 RUS82081.1 - 7e-10 38.5 0.1 9e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Ank_4 PF13637.6 RUS82082.1 - 1.5e-08 35.0 0.5 9.5e-05 22.9 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS82082.1 - 5.2e-08 33.4 0.8 0.0012 19.4 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS82082.1 - 7.2e-06 26.0 1.3 0.028 14.9 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RUS82082.1 - 1.7e-05 25.0 1.0 0.052 13.9 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS82082.1 - 0.00096 19.5 6.2 0.77 10.3 0.3 4.3 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_M56 PF05569.11 RUS82082.1 - 0.016 14.4 0.9 0.035 13.3 0.9 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 Metallophos PF00149.28 RUS82083.1 - 1.2e-05 25.9 0.1 1.6e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 RUS82083.1 - 0.14 11.5 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily EGF PF00008.27 RUS82084.1 - 2.8e-06 27.5 1.0 2.8e-06 27.5 1.0 2.3 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 RUS82084.1 - 0.00087 19.4 3.6 0.0022 18.1 3.6 1.7 1 1 0 1 1 1 1 Laminin EGF domain EphA2_TM PF14575.6 RUS82084.1 - 0.0066 17.3 0.0 0.019 15.9 0.1 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.13 RUS82084.1 - 0.0078 16.6 3.2 0.0078 16.6 3.2 2.2 2 1 0 2 2 2 1 EGF-like domain DUF1180 PF06679.12 RUS82084.1 - 0.029 14.8 1.9 0.17 12.3 1.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5367 PF17329.2 RUS82084.1 - 0.05 13.7 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5367) cEGF PF12662.7 RUS82084.1 - 0.089 12.8 3.1 0.16 11.9 0.3 2.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Resistin PF06954.11 RUS82084.1 - 4.8 7.8 9.0 0.54 10.8 4.0 2.0 3 0 0 3 3 3 0 Resistin Endotoxin_C PF03944.14 RUS82085.1 - 0.11 12.9 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 delta endotoxin 7TM_GPCR_Srx PF10328.9 RUS82086.1 - 5.8e-12 45.8 10.1 5.8e-12 45.8 10.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS82086.1 - 1e-07 31.6 18.7 1e-07 31.6 18.7 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82086.1 - 7.5e-07 28.7 15.5 2.1e-06 27.3 15.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF1189 PF06691.11 RUS82086.1 - 0.036 13.6 0.6 0.036 13.6 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) 7TM_GPCR_Srt PF10321.9 RUS82086.1 - 0.66 8.9 16.4 3.6 6.5 16.4 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt HlyE PF06109.13 RUS82086.1 - 1.1 8.5 3.0 4.6 6.5 0.1 2.4 1 1 1 2 2 2 0 Haemolysin E (HlyE) DUF4064 PF13273.6 RUS82086.1 - 4.4 7.6 11.0 4.9 7.5 0.4 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF4064) ACDC PF14733.6 RUS82087.1 - 0.045 14.1 2.5 6 7.3 0.8 3.7 3 1 0 3 3 3 0 AP2-coincident C-terminal SAM_Ste50p PF09235.10 RUS82087.1 - 0.074 13.3 0.3 4.7 7.5 0.0 3.0 2 0 0 2 2 2 0 Ste50p, sterile alpha motif TPR_19 PF14559.6 RUS82087.1 - 0.13 12.8 0.1 0.38 11.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HATPase_c_3 PF13589.6 RUS82088.1 - 2.2e-16 60.0 0.2 4e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS82088.1 - 3.8e-06 27.4 0.2 8e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_membrane_2 PF06472.15 RUS82089.1 - 7.8e-48 163.2 1.6 9.9e-48 162.9 1.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RUS82089.1 - 3.9e-07 30.7 0.1 1.4e-06 28.9 0.0 1.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 RUS82089.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RUS82089.1 - 0.0011 19.5 1.5 0.0042 17.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 RUS82089.1 - 0.0052 16.5 0.2 0.021 14.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 RUS82089.1 - 0.0088 15.4 0.2 0.15 11.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RUS82089.1 - 0.0095 15.9 0.3 0.033 14.1 0.0 2.0 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_15 PF13175.6 RUS82089.1 - 0.019 14.7 0.1 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 RUS82089.1 - 0.038 12.8 0.3 0.07 11.9 0.3 1.6 1 1 1 2 2 2 0 Adenovirus IVa2 protein AAA_27 PF13514.6 RUS82089.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS82089.1 - 0.064 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 RUS82089.1 - 0.072 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MIF4G PF02854.19 RUS82091.1 - 7.1e-66 221.9 19.9 1.7e-36 125.8 0.0 4.0 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 RUS82091.1 - 6.1e-29 101.5 12.1 6.1e-29 101.5 12.1 3.6 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Muskelin_N PF06588.11 RUS82092.1 - 1.1e-80 270.2 0.3 2.1e-80 269.4 0.3 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 RUS82092.1 - 5.8e-26 90.2 5.1 6.5e-09 35.9 0.2 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS82092.1 - 1.7e-17 63.0 5.2 0.0016 18.7 0.1 5.8 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 RUS82092.1 - 2.1e-17 62.8 7.3 0.00025 21.0 0.3 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS82092.1 - 3e-13 49.4 0.5 0.0077 16.2 0.0 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 RUS82092.1 - 4e-13 48.7 15.8 2e-05 24.0 0.3 5.9 5 1 0 5 5 5 4 Kelch motif F5_F8_type_C PF00754.25 RUS82092.1 - 7.4e-07 29.3 0.0 2.5e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.15 RUS82092.1 - 7.6e-06 25.7 12.4 0.00072 19.4 0.2 5.6 6 0 0 6 6 6 1 Kelch motif Sad1_UNC PF07738.13 RUS82092.1 - 0.032 14.3 0.0 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal LSM PF01423.22 RUS82093.1 - 7.2e-20 70.4 0.1 8.9e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain tRNA_Me_trans PF03054.16 RUS82094.1 - 1.1e-120 402.7 0.0 1.3e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 RUS82094.1 - 2.7e-07 30.0 0.0 5.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 RUS82094.1 - 9.2e-06 25.4 0.0 4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 RUS82094.1 - 0.0017 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 RUS82094.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 RUS82094.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 PP-loop family Y_phosphatase3 PF13350.6 RUS82095.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 RUS82095.1 - 0.00021 20.3 0.1 0.00069 18.6 0.1 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 RUS82095.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Rad52_Rad22 PF04098.15 RUS82096.1 - 3.8e-46 156.8 0.0 6.1e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ECM1 PF05782.11 RUS82096.1 - 0.04 12.8 1.8 0.055 12.4 1.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Lig_chan PF00060.26 RUS82097.1 - 4.8e-06 26.5 0.0 8.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel LAT PF15234.6 RUS82097.1 - 0.011 15.5 1.1 0.02 14.6 1.1 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Lig_chan-Glu_bd PF10613.9 RUS82097.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Sema PF01403.19 RUS82099.1 - 1e-118 396.9 0.1 1.2e-118 396.7 0.1 1.0 1 0 0 1 1 1 1 Sema domain DUF4542 PF15075.6 RUS82100.1 - 4.9e-18 65.8 0.2 3.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4542) OAD_gamma PF04277.13 RUS82101.1 - 0.0083 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain CD34_antigen PF06365.12 RUS82101.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family PTP_tm PF18861.1 RUS82101.1 - 0.045 13.7 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5305 PF17231.2 RUS82101.1 - 0.055 12.9 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 RUS82101.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family PIRT PF15099.6 RUS82101.1 - 0.063 12.9 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Insulin_TMD PF17870.1 RUS82101.1 - 0.069 13.2 0.9 0.12 12.5 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1180 PF06679.12 RUS82101.1 - 0.07 13.6 1.0 0.39 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sec66 PF09802.9 RUS82101.1 - 0.079 12.5 0.6 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 TMEMspv1-c74-12 PF11044.8 RUS82101.1 - 0.12 12.4 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein OppC_N PF12911.7 RUS82101.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Vpu PF00558.19 RUS82101.1 - 0.12 12.1 2.4 7.1 6.5 0.2 2.4 2 0 0 2 2 2 0 Vpu protein EphA2_TM PF14575.6 RUS82101.1 - 0.13 13.1 0.0 0.29 12.0 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2206 PF09971.9 RUS82101.1 - 0.17 10.6 0.3 0.25 10.0 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) 7tm_2 PF00002.24 RUS82102.1 - 5.6e-44 150.3 15.2 9.1e-44 149.6 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS82102.1 - 8.1e-15 54.9 1.4 1.6e-14 54.0 1.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain Alg14 PF08660.11 RUS82102.1 - 0.27 11.2 6.3 2.2 8.2 0.2 2.8 3 0 0 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like DUF4659 PF15558.6 RUS82103.1 - 5.5e-23 81.4 91.8 6.1e-23 81.3 91.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4659) Exo_endo_phos_2 PF14529.6 RUS82105.1 - 8e-06 25.7 1.6 8e-06 25.7 1.6 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 RUS82106.1 - 0.019 14.5 0.0 2.1 7.8 0.0 2.2 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7_N PF15402.6 RUS82106.1 - 0.028 12.7 0.0 0.036 12.3 0.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-RING_2 PF13639.6 RUS82107.1 - 1.1e-10 41.7 3.0 1.5e-10 41.2 1.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS82107.1 - 1.1e-09 37.8 1.4 1.1e-09 37.8 1.4 2.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS82107.1 - 4.7e-08 32.7 2.5 4.7e-08 32.7 2.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82107.1 - 1.1e-07 31.6 0.9 1.1e-07 31.6 0.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS82107.1 - 1.2e-07 31.9 2.2 3e-07 30.6 2.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS82107.1 - 4.2e-06 26.7 2.9 4.2e-06 26.7 2.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS82107.1 - 1.3e-05 25.1 0.4 2.8e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS82107.1 - 0.00069 19.4 0.2 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS82107.1 - 0.00094 19.2 1.2 0.0019 18.2 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RUS82107.1 - 0.0042 16.7 3.0 0.0099 15.5 3.0 1.6 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RUS82107.1 - 0.0092 15.8 1.3 0.023 14.6 1.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 RUS82107.1 - 0.023 15.0 2.1 0.049 13.9 0.3 2.2 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 RUS82107.1 - 0.13 12.5 2.5 0.16 12.1 1.0 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 RUS82107.1 - 0.17 11.8 3.1 6.1 6.8 0.7 2.9 3 0 0 3 3 3 0 PHD-finger zf-C3HC4_4 PF15227.6 RUS82107.1 - 0.27 11.4 3.7 0.37 11.0 1.9 2.1 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 RUS82107.1 - 1.3 9.0 4.4 1.8 8.6 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 RUS82107.1 - 2.6 8.2 4.5 1.3 9.2 1.4 2.2 2 1 0 2 2 2 0 RING-variant domain DUF1387 PF07139.11 RUS82108.1 - 1.5e-56 192.4 8.5 1.5e-56 192.4 8.5 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1387) CUE PF02845.16 RUS82108.1 - 0.055 13.2 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 CUE domain YojJ PF10372.9 RUS82108.1 - 0.071 13.2 0.5 0.26 11.4 0.5 2.0 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Fzo_mitofusin PF04799.13 RUS82108.1 - 9.1 5.8 7.1 4.4 6.8 2.1 2.7 2 1 1 3 3 3 0 fzo-like conserved region AIG1 PF04548.16 RUS82110.1 - 2.4e-48 164.3 0.5 2.4e-48 164.3 0.5 2.3 2 1 1 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 RUS82110.1 - 6e-07 29.5 0.2 2.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 RUS82110.1 - 0.0011 18.3 0.1 0.0011 18.3 0.1 2.6 2 1 1 3 3 3 1 Septin FeoB_N PF02421.18 RUS82110.1 - 0.013 15.1 0.0 0.038 13.5 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 RUS82110.1 - 0.054 13.0 0.1 0.17 11.4 0.1 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region Imm40 PF15569.6 RUS82110.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 40 AAA PF00004.29 RUS82110.1 - 5.4 7.5 7.3 12 6.3 0.0 3.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Serendipity_A PF05482.12 RUS82111.1 - 0.072 11.7 0.1 0.098 11.3 0.1 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) SNARE PF05739.19 RUS82112.1 - 1.1e-05 25.3 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 SNARE domain RTX PF02382.15 RUS82112.1 - 0.0059 16.3 0.3 0.0094 15.7 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein ApoO PF09769.9 RUS82112.1 - 0.029 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O Tropomyosin PF00261.20 RUS82112.1 - 0.042 13.2 2.8 0.53 9.6 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin DUF3482 PF11981.8 RUS82112.1 - 0.76 9.1 4.6 1.1 8.6 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3482) 7tm_3 PF00003.22 RUS82113.1 - 3.2e-54 184.2 14.9 4.7e-54 183.6 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 RUS82113.1 - 3.4e-34 118.5 0.1 4.7e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS82113.1 - 2.9e-06 27.2 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein GEN1_C PF18380.1 RUS82113.1 - 0.027 15.3 1.3 0.061 14.2 1.3 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 RUS82113.1 - 0.058 13.8 16.3 0.14 12.6 16.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMF_DNA_bd PF12329.8 RUS82113.1 - 0.063 13.3 1.3 0.17 11.9 1.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NOA36 PF06524.12 RUS82113.1 - 0.07 12.4 17.9 0.11 11.7 17.9 1.2 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 RUS82113.1 - 0.11 12.6 5.1 0.23 11.6 5.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein RXT2_N PF08595.11 RUS82113.1 - 0.18 11.8 8.4 0.18 11.8 7.0 1.7 2 0 0 2 2 1 0 RXT2-like, N-terminal CDC45 PF02724.14 RUS82113.1 - 0.32 9.3 8.5 0.61 8.3 8.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RUS82113.1 - 2.1 8.1 5.3 4.8 6.9 5.3 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 RUS82113.1 - 3.9 5.4 5.4 5.8 4.9 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 RUS82113.1 - 4.7 6.5 12.0 7.4 5.9 12.0 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RUS82113.1 - 5.7 6.8 10.3 0.67 9.8 5.9 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region PPP4R2 PF09184.11 RUS82113.1 - 5.9 6.4 8.3 9.9 5.7 8.3 1.2 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 RUS82113.1 - 6.3 5.2 13.5 10 4.5 13.5 1.2 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.11 RUS82113.1 - 9.6 4.6 10.4 16 3.9 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peripla_BP_6 PF13458.6 RUS82114.1 - 0.0006 19.6 0.0 0.00079 19.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 RUS82114.1 - 0.0084 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region SAPS PF04499.15 RUS82114.1 - 0.057 12.2 7.5 0.065 12.0 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS82114.1 - 0.42 10.0 43.5 0.55 9.6 43.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS82114.1 - 0.76 7.9 42.0 0.93 7.6 42.0 1.1 1 0 0 1 1 1 0 Nop14-like family EF-hand_7 PF13499.6 RUS82115.1 - 2.1e-09 37.7 0.1 3.6e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS82115.1 - 6e-08 32.4 0.7 6.8e-07 29.0 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS82115.1 - 1e-07 30.9 1.3 0.00061 19.2 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS82115.1 - 1.2e-07 31.1 1.0 0.0019 18.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS82115.1 - 0.0047 16.4 2.2 0.012 15.0 0.3 2.2 2 0 0 2 2 2 1 EF hand DUF2286 PF10051.9 RUS82115.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) Polyoma_lg_T_C PF06431.11 RUS82115.1 - 0.096 11.5 0.1 0.15 10.9 0.0 1.4 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus EF-hand_4 PF12763.7 RUS82115.1 - 0.098 12.6 0.1 0.56 10.2 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Suf PF05843.14 RUS82116.1 - 0.48 10.4 22.8 0.67 9.9 22.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Utp14 PF04615.13 RUS82116.1 - 0.51 8.9 37.4 0.65 8.5 37.4 1.0 1 0 0 1 1 1 0 Utp14 protein Androgen_recep PF02166.16 RUS82117.1 - 0.078 11.8 3.9 0.088 11.6 3.9 1.3 1 0 0 1 1 1 0 Androgen receptor VIR_N PF15912.5 RUS82117.1 - 0.91 9.1 5.8 1.1 8.8 5.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Pap_E4 PF02711.14 RUS82117.1 - 2.8 9.0 10.6 0.12 13.3 3.5 2.1 1 1 1 2 2 2 0 E4 protein Ras PF00071.22 RUS82118.1 - 8.5e-55 184.8 1.8 1e-54 184.5 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS82118.1 - 1.3e-33 115.8 1.0 1.8e-33 115.3 0.5 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS82118.1 - 5.7e-19 68.2 0.4 9.2e-19 67.6 0.2 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS82118.1 - 1.8e-09 37.7 0.3 5.8e-09 36.0 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS82118.1 - 3.9e-08 33.1 0.5 1.2e-07 31.5 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RUS82118.1 - 1.5e-07 31.0 0.3 1.7e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS82118.1 - 5.8e-06 26.3 0.2 0.005 16.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RUS82118.1 - 0.00098 18.7 0.3 0.0033 16.9 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RUS82118.1 - 0.0032 17.5 2.7 0.99 9.4 0.0 2.7 3 0 0 3 3 3 2 Dynamin family TniB PF05621.11 RUS82118.1 - 0.0038 16.6 0.0 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA PF00004.29 RUS82118.1 - 0.0063 16.9 0.2 0.16 12.4 0.0 2.1 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 RUS82118.1 - 0.0068 16.2 2.0 0.11 12.3 0.4 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 RUS82118.1 - 0.0071 15.6 0.1 0.39 9.8 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.27 RUS82118.1 - 0.01 16.4 0.3 0.16 12.5 0.3 2.4 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 RUS82118.1 - 0.012 15.2 0.3 0.034 13.7 0.1 1.9 1 1 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 RUS82118.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RUS82118.1 - 0.033 13.9 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RUS82118.1 - 0.033 14.5 0.3 2.3 8.5 0.0 2.2 1 1 0 2 2 2 0 AAA domain MCM PF00493.23 RUS82118.1 - 0.04 13.0 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain CENP-M PF11111.8 RUS82118.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) T2SSF PF00482.23 RUS82118.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Trypsin_2 PF13365.6 RUS82119.1 - 1.1e-08 36.2 0.0 1.8e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Uso1_p115_head PF04869.14 RUS82119.1 - 0.034 13.3 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region 2OG-FeII_Oxy_3 PF13640.6 RUS82121.1 - 1.8e-10 41.6 0.0 4.4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps54_N PF10475.9 RUS82121.1 - 0.019 14.3 1.4 0.056 12.7 0.1 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Oxygenase-NA PF09859.9 RUS82121.1 - 0.051 13.1 0.2 1.9 8.0 0.2 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy_5 PF13759.6 RUS82121.1 - 0.076 13.4 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_4 PF13661.6 RUS82121.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_S24 PF00717.23 RUS82122.1 - 9.9e-07 28.6 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RUS82122.1 - 9.9e-06 25.4 0.0 0.054 13.3 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 LRR_8 PF13855.6 RUS82123.1 - 1.2e-29 101.8 25.0 6e-13 48.3 2.3 5.8 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 RUS82123.1 - 4.8e-15 55.4 28.0 8.6e-07 29.2 1.3 5.5 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS82123.1 - 2.8e-06 26.9 7.1 0.0055 16.2 1.0 2.7 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 RUS82123.1 - 1.2e-05 24.8 2.8 0.00046 19.8 0.5 2.8 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 RUS82123.1 - 4.9e-05 23.3 17.0 0.68 10.7 0.3 7.9 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_5 PF13306.6 RUS82123.1 - 0.085 12.8 0.0 4.3 7.3 0.0 2.5 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 RUS82123.1 - 0.11 12.6 18.3 12 6.2 0.2 7.4 6 1 1 7 7 7 0 Leucine Rich repeat ComP_DUS PF16732.5 RUS82124.1 - 0.013 16.4 16.1 4.6 8.2 0.7 4.5 1 1 2 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor Stap_Strp_tox_C PF02876.17 RUS82124.1 - 0.11 12.8 20.7 23 5.4 0.6 6.5 1 1 8 9 9 9 0 Staphylococcal/Streptococcal toxin, beta-grasp domain MRP-63 PF14978.6 RUS82124.1 - 0.25 12.0 22.7 16 6.2 3.3 4.0 1 1 2 3 3 3 0 Mitochondrial ribosome protein 63 ATP-synt PF00231.19 RUS82125.1 - 2e-79 267.2 2.4 2.2e-79 267.1 2.4 1.0 1 0 0 1 1 1 1 ATP synthase BTG PF07742.12 RUS82126.1 - 8.9e-25 86.8 0.0 1.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 BTG family MADF_DNA_bdg PF10545.9 RUS82127.1 - 1.1e-16 60.9 1.6 2.6e-16 59.7 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 RUS82127.1 - 3e-07 30.4 2.3 3e-07 30.4 2.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain BESS PF02944.20 RUS82127.1 - 4e-07 29.7 0.3 7.8e-07 28.8 0.3 1.5 1 0 0 1 1 1 1 BESS motif Ins_P5_2-kin PF06090.12 RUS82127.1 - 1.9e-06 27.6 2.2 1.9e-06 27.6 2.2 1.6 1 1 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase Myb_DNA-bind_4 PF13837.6 RUS82127.1 - 0.00092 19.5 1.3 0.00092 19.5 1.3 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SDA1 PF05285.12 RUS82128.1 - 0.00014 21.5 53.6 0.00016 21.2 53.6 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS82128.1 - 0.0026 16.1 53.1 0.0029 15.9 53.1 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 RUS82128.1 - 0.019 14.4 41.9 0.026 13.9 41.9 1.3 1 0 0 1 1 1 0 BUD22 RNA_polI_A34 PF08208.11 RUS82128.1 - 0.21 11.7 28.1 0.33 11.0 28.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SID-1_RNA_chan PF13965.6 RUS82128.1 - 0.31 9.4 5.2 0.34 9.3 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 RUS82128.1 - 0.62 8.1 15.4 0.61 8.1 15.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIP5K PF01504.18 RUS82128.1 - 0.67 9.1 9.5 0.73 9.0 9.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.22 RUS82128.1 - 0.83 8.8 14.7 1.1 8.4 14.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 RUS82128.1 - 1.8 8.6 7.4 1.8 8.5 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 RUS82128.1 - 3.5 7.0 25.2 6.3 6.2 25.2 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PA26 PF04636.13 RUS82128.1 - 3.7 6.4 11.5 3.7 6.3 11.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 RUS82128.1 - 3.8 6.4 16.1 4.3 6.2 16.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CobS_N PF12556.8 RUS82129.1 - 0.00014 21.5 0.0 95 2.8 0.0 6.0 6 1 0 6 6 6 0 Cobaltochelatase CobS subunit N terminal TrbM PF07424.11 RUS82129.1 - 0.023 14.7 2.4 7.4 6.5 0.1 3.2 1 1 2 3 3 3 0 TrbM Ins_P5_2-kin PF06090.12 RUS82129.1 - 0.098 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DUF3504 PF12012.8 RUS82129.1 - 0.49 10.3 9.0 3.6 7.5 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3504) Toxin_24 PF08094.11 RUS82129.1 - 6.5 6.7 37.3 9 6.2 0.4 7.4 8 0 0 8 8 8 0 Conotoxin TVIIA/GS family Cadherin PF00028.17 RUS82130.1 - 2.5e-161 524.7 23.0 2.3e-21 76.0 0.3 9.4 9 0 0 9 9 9 9 Cadherin domain Laminin_G_2 PF02210.24 RUS82130.1 - 7.6e-36 123.5 1.6 5.2e-20 72.3 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain 7tm_2 PF00002.24 RUS82130.1 - 9.1e-34 116.8 23.7 1.4e-33 116.2 23.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_1 PF00054.23 RUS82130.1 - 4.6e-28 98.1 0.2 2.8e-19 69.6 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain GAIN PF16489.5 RUS82130.1 - 2.9e-20 72.6 1.0 4.8e-20 71.9 1.0 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Cadherin_3 PF16184.5 RUS82130.1 - 7.6e-13 48.4 16.1 0.012 15.6 0.1 8.4 8 0 0 8 8 8 4 Cadherin-like EGF PF00008.27 RUS82130.1 - 2.5e-10 40.4 83.5 2.4e-07 30.9 8.5 6.9 6 0 0 6 6 5 4 EGF-like domain Laminin_EGF PF00053.24 RUS82130.1 - 9.5e-10 38.5 9.5 9.5e-10 38.5 9.5 8.5 5 2 3 8 8 6 2 Laminin EGF domain Cadherin_2 PF08266.12 RUS82130.1 - 8.3e-09 35.2 0.1 11 6.0 0.0 7.8 9 0 0 9 9 8 1 Cadherin-like GPS PF01825.21 RUS82130.1 - 1.2e-05 25.7 7.1 1.2e-05 25.7 7.1 3.1 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif Laminin_G_3 PF13385.6 RUS82130.1 - 3.7e-05 23.9 5.9 0.017 15.3 0.1 3.5 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 RUS82130.1 - 0.00016 22.2 5.3 0.00016 22.2 5.3 6.8 6 0 0 6 6 6 2 Human growth factor-like EGF EGF_2 PF07974.13 RUS82130.1 - 0.0033 17.8 8.0 0.0033 17.8 8.0 7.7 7 1 1 8 8 6 2 EGF-like domain EGF_CA PF07645.15 RUS82130.1 - 0.0039 17.3 7.4 0.0039 17.3 7.4 6.3 5 1 1 6 6 2 1 Calcium-binding EGF domain Y_Y_Y PF07495.13 RUS82130.1 - 0.092 12.7 1.2 76 3.4 0.0 5.4 6 0 0 6 6 6 0 Y_Y_Y domain Lipocalin PF00061.23 RUS82131.1 - 3.2e-11 43.6 0.9 3.8e-11 43.4 0.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS82131.1 - 1.8e-06 27.9 0.4 2.7e-06 27.3 0.4 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lactamase_B_2 PF12706.7 RUS82132.1 - 2.6e-32 112.0 0.0 4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS82132.1 - 1.3e-08 34.9 0.0 3.2e-08 33.7 0.0 1.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 RUS82132.1 - 0.0077 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Meiosis_expr PF15163.6 RUS82133.1 - 1.1e-37 128.5 5.1 1.2e-37 128.4 5.1 1.0 1 0 0 1 1 1 1 Meiosis-expressed Transket_pyr PF02779.24 RUS82134.1 - 3e-45 154.1 0.1 4.9e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RUS82134.1 - 7.1e-40 135.7 0.1 1.5e-39 134.7 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mito_carr PF00153.27 RUS82135.1 - 5.6e-48 160.8 7.2 6.7e-18 64.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA_m1G_MT PF01746.21 RUS82136.1 - 3e-21 76.0 0.0 6.1e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PX PF00787.24 RUS82137.1 - 1.3e-17 63.7 0.6 6.5e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 PX domain WH2 PF02205.20 RUS82137.1 - 3.1e-10 39.5 3.1 3.8e-09 36.1 0.9 2.4 2 0 0 2 2 2 1 WH2 motif Pkinase_Tyr PF07714.17 RUS82137.1 - 2.1e-06 27.2 0.0 5.4e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS82137.1 - 9e-06 25.2 0.0 0.00025 20.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain SMN PF06003.12 RUS82137.1 - 2.5 7.3 15.5 4.2 6.6 15.5 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Rrn6 PF10214.9 RUS82137.1 - 7.3 4.9 7.0 11 4.4 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TMEM252 PF15664.5 RUS82138.1 - 0.0007 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Transmembrane protein 252 family Ly49 PF08391.10 RUS82138.1 - 0.01 16.2 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Neur_chan_memb PF02932.16 RUS82138.1 - 0.019 15.1 6.8 0.25 11.4 6.8 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.6 RUS82138.1 - 0.064 14.1 0.1 0.27 12.1 0.1 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 RUS82138.1 - 0.12 13.1 4.6 0.2 12.4 0.0 2.9 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Syndecan PF01034.20 RUS82138.1 - 0.18 11.8 0.9 0.28 11.1 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.6 RUS82138.1 - 0.77 10.2 2.8 2.1 8.8 0.1 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT EGF PF00008.27 RUS82141.1 - 2.8e-22 78.7 93.4 1.5e-07 31.6 5.7 7.8 7 0 0 7 7 7 6 EGF-like domain hEGF PF12661.7 RUS82141.1 - 9.5e-09 35.6 77.3 0.0053 17.3 2.7 8.6 7 1 1 8 8 8 5 Human growth factor-like EGF EGF_3 PF12947.7 RUS82141.1 - 3.4e-06 27.1 78.1 0.00013 22.0 2.4 7.5 7 1 0 7 7 7 6 EGF domain EGF_2 PF07974.13 RUS82141.1 - 2.4e-05 24.6 107.5 0.00057 20.2 8.9 7.7 8 0 0 8 8 8 5 EGF-like domain Cadherin PF00028.17 RUS82141.1 - 0.17 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Cadherin domain EGF_CA PF07645.15 RUS82141.1 - 3.8 7.8 89.1 0.045 14.0 11.6 7.9 3 3 4 7 7 7 0 Calcium-binding EGF domain Laminin_EGF PF00053.24 RUS82141.1 - 7.1 6.9 77.0 7.1 6.9 10.0 7.0 1 1 5 6 6 6 0 Laminin EGF domain 7tm_2 PF00002.24 RUS82142.1 - 5.1e-36 124.2 20.3 7.4e-36 123.7 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS82142.1 - 2e-11 44.2 2.7 2e-11 44.2 2.7 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF4408 PF14364.6 RUS82142.1 - 0.0089 15.7 1.3 0.037 13.7 1.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4408) GAIN PF16489.5 RUS82142.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.6 1 1 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain NgoMIV_restric PF09015.10 RUS82142.1 - 0.037 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme Lectin_C PF00059.21 RUS82143.1 - 1.3e-10 42.0 1.1 2.7e-10 41.0 0.2 2.1 2 0 0 2 2 2 1 Lectin C-type domain C2-set_2 PF08205.12 RUS82143.1 - 0.0052 16.8 1.4 0.026 14.6 0.0 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain DDE_Tnp_1_7 PF13843.6 RUS82144.1 - 1.6e-28 100.1 0.0 6.3e-23 81.6 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 Ion_trans_2 PF07885.16 RUS82145.1 - 1.2e-27 95.6 26.6 6.2e-14 51.7 9.7 3.5 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.31 RUS82145.1 - 2.2e-05 23.8 14.6 2.7e-05 23.5 1.0 2.3 2 0 0 2 2 2 2 Ion transport protein CrgA PF06781.12 RUS82145.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.9 3 1 0 3 3 3 0 Cell division protein CrgA Pkinase PF00069.25 RUS82148.1 - 1.6e-53 181.8 0.0 3.9e-52 177.2 0.0 2.8 2 0 0 2 2 2 1 Protein kinase domain CNH PF00780.22 RUS82148.1 - 9.9e-52 176.2 0.1 1.9e-51 175.3 0.1 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 RUS82148.1 - 1.7e-28 99.6 0.0 6.4e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 Protein tyrosine kinase KELK PF15796.5 RUS82148.1 - 1.3e-19 70.5 17.2 1.3e-19 70.5 17.2 6.5 5 1 1 6 6 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase C1_1 PF00130.22 RUS82148.1 - 6.1e-10 38.8 8.1 1.5e-09 37.5 8.1 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PBD PF00786.28 RUS82148.1 - 1.5e-07 31.6 1.1 0.00021 21.6 0.1 3.2 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.6 RUS82148.1 - 3.3e-07 29.9 0.2 1.1e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 RUS82148.1 - 2.4e-05 24.8 0.0 9.5e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 PH domain Myosin_tail_1 PF01576.19 RUS82148.1 - 2.6e-05 22.3 75.4 2.6e-05 22.3 75.4 3.7 1 1 2 3 3 3 1 Myosin tail DMPK_coil PF08826.10 RUS82148.1 - 4e-05 23.6 12.9 4e-05 23.6 12.9 8.8 7 2 3 10 10 9 2 DMPK coiled coil domain like Pkinase_C PF00433.24 RUS82148.1 - 0.0011 19.6 4.4 0.0038 17.9 4.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 RUS82148.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family FPP PF05911.11 RUS82148.1 - 5.4 5.1 78.5 2.6 6.1 33.2 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Glyco_hydro_31 PF01055.26 RUS82149.1 - 1.1e-144 483.0 5.9 1.5e-144 482.5 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RUS82149.1 - 2.8e-25 88.4 1.8 1.8e-23 82.6 0.7 3.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 RUS82149.1 - 0.0003 21.0 0.0 0.00086 19.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Metallophos PF00149.28 RUS82150.1 - 7.1e-20 72.4 0.7 1.4e-19 71.4 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 RUS82150.1 - 3.6e-19 69.4 0.1 1.4e-18 67.5 0.1 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 RUS82150.1 - 1.9e-18 66.8 0.5 1.9e-18 66.8 0.5 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 RUS82150.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 RUS82150.1 - 0.027 15.0 0.1 0.082 13.5 0.1 1.8 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain RT_RNaseH_2 PF17919.1 RUS82151.1 - 8.2e-34 115.6 0.0 2.7e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS82151.1 - 2.8e-33 114.4 0.0 7.4e-33 113.0 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS82151.1 - 4.3e-22 78.7 0.0 6.3e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypsin_2 PF13365.6 RUS82152.1 - 3.5e-16 60.4 0.2 7.5e-16 59.4 0.2 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RUS82152.1 - 0.00092 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 RUS82152.1 - 0.26 9.9 0.1 0.37 9.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Doppel PF11466.8 RUS82152.1 - 2.2 8.0 4.5 3.8 7.2 2.9 2.0 2 0 0 2 2 2 0 Prion-like protein Doppel PDZ_2 PF13180.6 RUS82153.1 - 5.2e-12 45.9 0.1 9e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS82153.1 - 2.5e-11 43.2 0.0 4.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS82153.1 - 6.6e-09 36.0 0.1 1.1e-08 35.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 RUS82153.1 - 0.00039 20.3 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain Trypsin PF00089.26 RUS82153.1 - 0.01 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 RUS82153.1 - 0.1 13.5 0.2 0.18 12.7 0.2 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain GRASP55_65 PF04495.14 RUS82153.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF5344 PF17279.2 RUS82154.1 - 0.17 12.4 4.5 5.2 7.7 0.1 4.6 3 1 1 4 4 4 0 Family of unknown function (DUF5344) CLZ PF16526.5 RUS82154.1 - 3.2 8.2 6.3 4.2 7.8 0.1 4.1 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Galactosyl_T PF01762.21 RUS82156.1 - 9.7e-25 87.5 0.0 1.2e-19 70.9 0.0 2.9 3 0 0 3 3 3 2 Galactosyltransferase Fringe PF02434.16 RUS82156.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF3695 PF12494.8 RUS82157.1 - 0.039 13.8 1.4 0.098 12.5 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) 7tm_1 PF00001.21 RUS82158.1 - 1.3e-28 100.0 21.2 2e-28 99.5 21.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS82158.1 - 6.8e-08 32.2 24.7 9.6e-08 31.7 23.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS82158.1 - 0.077 12.3 26.8 0.26 10.5 3.1 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Cytochrome-c551 PF10643.9 RUS82158.1 - 5 6.7 11.5 0.087 12.4 1.2 2.2 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 LapA_dom PF06305.11 RUS82158.1 - 6.8 6.6 7.6 17 5.3 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4821 PF16092.5 RUS82159.1 - 8.8e-94 314.0 0.1 1.1e-93 313.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) CUB PF00431.20 RUS82160.1 - 7.6e-07 29.5 0.8 1.5e-06 28.5 0.8 1.5 1 0 0 1 1 1 1 CUB domain DUF1467 PF07330.12 RUS82160.1 - 0.038 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DUF4448 PF14610.6 RUS82160.1 - 0.068 12.9 0.7 5 6.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Tad PF13400.6 RUS82160.1 - 8.3 6.8 6.4 0.87 10.0 1.1 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like COesterase PF00135.28 RUS82161.1 - 5e-135 451.3 0.2 5.9e-135 451.0 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 RUS82161.1 - 3.7e-07 31.0 0.1 1.1e-06 29.4 0.0 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RUS82161.1 - 6.1e-05 23.0 0.2 0.00038 20.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS82161.1 - 0.006 16.1 0.6 0.01 15.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Imm27 PF15590.6 RUS82161.1 - 0.14 11.9 0.2 0.4 10.5 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 27 p450 PF00067.22 RUS82162.1 - 4.6e-58 197.1 0.2 5.4e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.18 RUS82163.1 - 1.6e-52 178.6 26.4 2e-52 178.3 26.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rib_hydrolayse PF02267.17 RUS82164.1 - 8.7e-62 208.7 0.0 9.8e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Sugar_tr PF00083.24 RUS82165.1 - 9.1e-32 110.5 15.5 1.3e-31 110.0 15.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS82165.1 - 5.6e-26 91.3 55.1 5.2e-19 68.4 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Otopetrin PF03189.13 RUS82167.1 - 9.6e-94 314.7 28.3 1.1e-63 215.6 12.6 3.0 2 1 1 3 3 3 3 Otopetrin AMIN PF11741.8 RUS82167.1 - 0.023 14.8 0.2 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 AMIN domain DUF4738 PF15889.5 RUS82167.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) ERK-JNK_inhib PF15002.6 RUS82168.1 - 1.8e-40 138.8 0.6 2.2e-40 138.4 0.6 1.1 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor DUF2433 PF10360.9 RUS82168.1 - 0.1 12.7 0.3 0.26 11.4 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) DUF4451 PF14616.6 RUS82168.1 - 0.11 12.8 0.4 3.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Yip1 PF04893.17 RUS82169.1 - 1.6e-15 57.2 9.3 1.6e-15 57.2 9.3 1.4 1 1 0 1 1 1 1 Yip1 domain Fcf2 PF08698.11 RUS82170.1 - 6.5e-35 119.4 1.3 6.5e-35 119.4 1.3 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Nup54 PF13874.6 RUS82171.1 - 4.5e-45 153.2 2.7 7e-45 152.6 2.7 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 RUS82171.1 - 1.2e-11 44.3 10.5 1.2e-11 44.3 10.5 2.1 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain Focal_AT PF03623.13 RUS82171.1 - 3.7 7.6 5.9 6.9 6.7 4.5 2.1 1 1 2 3 3 3 0 Focal adhesion targeting region Peptidase_M19 PF01244.21 RUS82172.1 - 4.6e-36 124.6 0.0 5.4e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF1720 PF08226.11 RUS82173.1 - 0.17 12.3 24.8 1.8e+04 -10.4 24.8 4.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Curlin_rpt PF07012.12 RUS82173.1 - 0.99 9.5 53.0 1.3 9.1 1.5 8.9 3 2 3 6 6 6 0 Curlin associated repeat YkpC PF17447.2 RUS82174.1 - 4.4 8.4 9.8 71 4.6 0.2 5.0 4 0 0 4 4 4 0 Uncharacterized YkpC-like DUF4131 PF13567.6 RUS82176.1 - 0.071 12.7 0.3 4.7 6.8 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CagY_I PF14585.6 RUS82176.1 - 1.6 8.9 9.2 53 4.0 0.1 4.4 4 0 0 4 4 4 0 CagY type 1 repeat Enoyl_reductase PF12241.8 RUS82177.1 - 0.43 9.9 66.3 10 5.3 2.7 8.0 1 1 3 6 6 6 0 Trans-2-enoyl-CoA reductase catalytic region CholecysA-Rec_N PF09193.10 RUS82178.1 - 0.00018 21.4 0.3 39 4.4 0.0 6.0 7 0 0 7 7 7 1 Cholecystokinin A receptor, N-terminal Auxin_BP PF02041.16 RUS82178.1 - 0.00048 19.8 1.4 29 4.3 0.0 5.0 6 0 0 6 6 6 3 Auxin binding protein YejG PF13989.6 RUS82178.1 - 0.0019 18.6 0.3 46 4.5 0.0 4.8 3 1 2 5 5 5 0 YejG-like protein VARLMGL PF14383.6 RUS82178.1 - 0.0024 17.4 0.8 80 2.9 0.0 4.8 5 0 0 5 5 5 0 DUF761-associated sequence motif Somatomedin_B PF01033.17 RUS82179.1 - 0.014 15.8 10.3 0.046 14.1 10.3 1.9 1 0 0 1 1 1 0 Somatomedin B domain PMG PF05287.12 RUS82180.1 - 0.00047 20.2 43.3 0.00077 19.5 43.3 1.3 1 1 0 1 1 1 1 PMG protein Glyco_hydro_18 PF00704.28 RUS82181.1 - 5.1e-54 184.1 0.1 9.2e-54 183.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ephrin_rec_like PF07699.13 RUS82181.1 - 1.2e-16 60.1 16.1 1.1e-10 41.1 4.4 2.8 2 0 0 2 2 2 2 Putative ephrin-receptor like Cuticle_4 PF15955.5 RUS82181.1 - 8.7e-09 36.0 27.0 1.4e+02 3.3 0.0 12.4 2 2 11 18 18 18 0 Cuticle protein EGF PF00008.27 RUS82181.1 - 0.0015 18.8 5.3 0.0038 17.5 5.3 1.8 1 0 0 1 1 1 1 EGF-like domain MetallophosN PF16371.5 RUS82182.1 - 0.00087 19.5 12.5 0.29 11.4 1.7 3.5 1 1 3 4 4 4 4 N terminal of Calcineurin-like phosphoesterase Dynein_light PF01221.18 RUS82182.1 - 0.97 9.8 24.2 13 6.2 0.6 5.2 1 1 4 6 6 6 0 Dynein light chain type 1 Glyco_hydro_18 PF00704.28 RUS82184.1 - 3.5e-35 122.2 0.0 3.9e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CPSase_L_D3 PF02787.19 RUS82185.1 - 0.0014 19.0 15.5 4.1 7.8 1.4 5.0 1 1 3 4 4 4 3 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RL PF17797.1 RUS82185.1 - 1.5 8.9 23.6 6.6 6.8 3.4 4.3 1 1 4 5 5 5 0 RL domain DUF4305 PF14146.6 RUS82185.1 - 4 7.7 29.8 26 5.1 0.4 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4305) PI-PLC-X PF00388.19 RUS82185.1 - 4.2 6.9 20.8 5.7 6.5 1.8 3.3 1 1 2 3 3 3 0 Phosphatidylinositol-specific phospholipase C, X domain Ald_Xan_dh_C2 PF02738.18 RUS82186.1 - 2.7e-78 263.8 0.0 3.4e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase MRNIP PF15749.5 RUS82187.1 - 1.9e-09 38.2 1.1 1.1e+02 3.6 0.0 9.2 10 0 0 10 10 10 0 MRN-interacting protein MliC PF09864.9 RUS82187.1 - 6.5e-07 29.2 3.3 53 3.9 0.0 10.0 12 1 0 12 12 12 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme BCA_ABC_TP_C PF12399.8 RUS82187.1 - 0.034 14.1 0.6 2.6e+02 1.7 0.0 4.9 5 0 0 5 5 5 0 Branched-chain amino acid ATP-binding cassette transporter gpUL132 PF11359.8 RUS82187.1 - 2.5 7.6 28.5 29 4.1 0.1 9.6 3 3 9 12 12 12 0 Glycoprotein UL132 Ald_Xan_dh_C2 PF02738.18 RUS82188.1 - 2.1e-42 145.3 0.1 3.2e-42 144.7 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 RUS82188.1 - 5.9e-29 99.9 0.2 1.7e-28 98.4 0.1 1.9 2 0 0 2 2 2 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 RUS82188.1 - 1.2e-27 96.7 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 RUS82188.1 - 8.9e-23 80.8 0.0 1.8e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 RUS82188.1 - 2e-11 44.0 0.0 4.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_4 PF01565.23 RUS82188.1 - 0.017 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain DUF2754 PF10953.8 RUS82189.1 - 0.024 14.9 0.7 2.2 8.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) Hep_core_N PF08290.11 RUS82189.1 - 1.4 8.9 12.3 6 7.0 0.6 3.3 3 0 0 3 3 3 0 Hepatitis core protein, putative zinc finger Peptidase_C14 PF00656.22 RUS82190.1 - 4.3e-34 118.6 0.0 5.2e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain zf-C3HC4 PF00097.25 RUS82191.1 - 6.7e-08 32.3 6.2 1.3e-07 31.4 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS82191.1 - 8e-07 29.1 3.5 8e-07 29.1 3.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS82191.1 - 1.2e-06 28.4 9.1 1.6e-06 28.0 5.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS82191.1 - 1.9e-06 27.6 3.2 1.9e-06 27.6 3.2 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS82191.1 - 2.2e-06 27.4 2.5 2.2e-06 27.4 2.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS82191.1 - 4.5e-06 26.9 3.2 4.5e-06 26.9 3.2 3.5 2 1 0 2 2 1 1 Ring finger domain zf-TRAF PF02176.18 RUS82191.1 - 5.3e-06 27.0 6.4 5.3e-06 27.0 6.4 4.0 2 1 2 4 4 3 1 TRAF-type zinc finger zf-RING_5 PF14634.6 RUS82191.1 - 8.1e-05 22.5 2.4 8.1e-05 22.5 2.4 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 RUS82191.1 - 0.00031 21.1 7.0 0.033 14.6 3.2 3.3 2 1 1 3 3 3 2 TRAF-like zinc-finger TolA_bind_tri PF16331.5 RUS82191.1 - 0.0065 16.5 0.9 0.15 12.1 3.6 1.8 2 0 0 2 2 2 1 TolA binding protein trimerisation zf-C3HC4_5 PF17121.5 RUS82191.1 - 0.008 16.0 4.6 0.04 13.8 4.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS82191.1 - 0.016 15.0 2.0 0.016 15.0 2.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 ATP-synt PF00231.19 RUS82191.1 - 0.025 14.3 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 ATP synthase ADIP PF11559.8 RUS82191.1 - 0.029 14.5 1.8 0.029 14.5 1.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sina PF03145.16 RUS82191.1 - 0.041 13.8 0.2 0.041 13.8 0.2 2.3 1 1 1 2 2 2 0 Seven in absentia protein family Mod_r PF07200.13 RUS82191.1 - 0.19 11.8 2.6 0.35 11.0 2.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DNA_RNApol_7kD PF03604.13 RUS82191.1 - 3.6 7.3 9.2 0.56 9.9 0.5 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Lectin_C PF00059.21 RUS82192.1 - 6.5e-36 123.3 1.3 1.6e-19 70.6 0.4 2.2 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 RUS82192.1 - 7e-05 22.6 1.1 0.11 12.1 0.1 2.5 1 1 1 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like GPS PF01825.21 RUS82192.1 - 0.19 12.3 5.3 0.62 10.6 0.7 2.7 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif DUF4777 PF16007.5 RUS82193.1 - 4.2e-05 23.7 1.5 12 6.2 0.0 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4777) FliG_M PF14841.6 RUS82193.1 - 0.0019 18.4 0.0 29 5.0 0.0 4.3 2 1 3 5 5 5 0 FliG middle domain DUF445 PF04286.12 RUS82193.1 - 0.0025 17.7 0.1 0.003 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) RFC1 PF08519.12 RUS82193.1 - 0.0037 17.5 8.7 2.3 8.4 0.4 4.1 1 1 3 4 4 4 1 Replication factor RFC1 C terminal domain ORF6C PF10552.9 RUS82193.1 - 0.0055 16.8 2.4 2.2 8.4 0.1 3.3 1 1 2 3 3 3 1 ORF6C domain Spo0A_C PF08769.11 RUS82193.1 - 0.0059 16.7 1.9 5.9 7.0 0.1 3.0 1 1 2 3 3 3 1 Sporulation initiation factor Spo0A C terminal TGS PF02824.21 RUS82193.1 - 0.01 15.9 0.0 58 3.8 0.0 4.4 5 0 0 5 5 5 0 TGS domain DUF4709 PF15821.5 RUS82193.1 - 0.021 15.1 2.9 0.15 12.3 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) Condensin2nSMC PF12422.8 RUS82193.1 - 0.025 14.8 0.1 0.073 13.2 0.1 1.7 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Speriolin_C PF15059.6 RUS82193.1 - 0.042 14.0 4.4 2.2 8.4 0.2 2.6 1 1 2 3 3 3 0 Speriolin C-terminus Phg_2220_C PF09524.10 RUS82193.1 - 0.043 13.9 3.4 2.1 8.5 0.1 3.3 1 1 2 4 4 4 0 Conserved phage C-terminus (Phg_2220_C) DUF507 PF04368.13 RUS82193.1 - 0.059 13.3 0.2 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF507) AAA_lid_6 PF17866.1 RUS82193.1 - 0.073 13.3 1.1 11 6.3 0.2 3.6 2 1 1 3 3 3 0 AAA lid domain RecX PF02631.16 RUS82193.1 - 1 9.9 4.9 12 6.4 0.7 2.5 1 1 1 2 2 2 0 RecX family RNA_pol_Rpb4 PF03874.16 RUS82193.1 - 2.4 8.5 5.8 80 3.6 5.8 2.3 1 1 0 1 1 1 0 RNA polymerase Rpb4 DEAD PF00270.29 RUS82194.1 - 1e-50 171.9 0.2 3e-50 170.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS82194.1 - 1.3e-32 112.4 0.5 4.4e-31 107.5 0.1 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS82194.1 - 1.2e-07 31.9 0.1 3.7e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RUS82194.1 - 1.7e-07 30.7 1.2 3.8e-07 29.6 1.2 1.6 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 RUS82194.1 - 0.029 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF4246 PF14033.6 RUS82194.1 - 0.42 9.7 3.2 0.33 10.0 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) CARD PF00619.21 RUS82195.1 - 1.1e-07 31.7 0.8 2.2e-07 30.8 0.8 1.5 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 RUS82195.1 - 0.0017 18.3 0.3 0.0035 17.3 0.3 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Fumerase_C PF05683.12 RUS82196.1 - 7.4e-88 293.2 0.0 1.2e-87 292.5 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 RUS82196.1 - 3.1e-87 292.4 0.0 4.1e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Colipase_C PF02740.14 RUS82196.1 - 0.06 13.5 0.2 0.2 11.9 0.2 1.8 1 0 0 1 1 1 0 Colipase, C-terminal domain NPR3 PF03666.13 RUS82199.1 - 0.094 11.5 3.6 0.13 11.0 3.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS82199.1 - 2.2 6.5 26.4 2.7 6.2 26.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2631 PF10939.8 RUS82200.1 - 0.021 14.7 0.2 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) zf-3CxxC PF13695.6 RUS82201.1 - 7.1e-26 90.6 0.3 7.9e-26 90.5 0.3 1.0 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 RUS82201.1 - 0.0016 19.1 4.3 0.86 10.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-binding domain PMT_4TMC PF16192.5 RUS82202.1 - 0.021 14.4 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase PsbX PF06596.11 RUS82203.1 - 0.0067 16.4 2.5 0.0096 15.9 2.5 1.2 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) EphA2_TM PF14575.6 RUS82203.1 - 0.054 14.4 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain cEGF PF12662.7 RUS82203.1 - 0.065 13.2 0.3 0.065 13.2 0.3 3.6 3 1 1 4 4 4 0 Complement Clr-like EGF-like TNFR_c6 PF00020.18 RUS82203.1 - 0.21 12.0 20.5 0.24 11.8 1.0 4.1 2 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region Pkinase PF00069.25 RUS82205.1 - 1.9e-30 106.2 0.0 3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82205.1 - 9.1e-21 74.3 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS82205.1 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS82205.1 - 0.065 13.2 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RUS82206.1 - 5.9e-24 84.8 0.0 6.9e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82206.1 - 2.2e-17 63.2 0.0 2.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS82206.1 - 0.0034 16.7 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS82206.1 - 0.033 14.1 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RUS82207.1 - 9.8e-31 107.1 0.0 1.4e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82207.1 - 8.7e-21 74.4 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS82207.1 - 1.5e-07 31.0 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS82207.1 - 0.061 13.2 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IL32 PF15225.6 RUS82208.1 - 0.08 13.3 0.5 0.11 12.9 0.5 1.2 1 0 0 1 1 1 0 Interleukin 32 DUF728 PF05304.12 RUS82208.1 - 0.12 12.3 3.2 0.15 11.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF728) RVT_1 PF00078.27 RUS82209.1 - 2.5e-63 213.6 4.4 1.2e-41 142.6 0.4 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ANXA2R PF15721.5 RUS82209.1 - 0.051 14.1 0.0 2.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Annexin-2 receptor Vitellogenin_N PF01347.22 RUS82210.1 - 2.1e-79 267.6 0.0 3.5e-79 266.9 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 RUS82210.1 - 2.7e-52 177.9 0.7 3.6e-52 177.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) zf-ZPR1 PF03367.13 RUS82210.1 - 0.079 12.8 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 ZPR1 zinc-finger domain VWD PF00094.25 RUS82211.1 - 1.1e-18 68.0 1.3 1.1e-18 68.0 1.3 3.4 2 0 0 2 2 2 1 von Willebrand factor type D domain DUF1081 PF06448.11 RUS82211.1 - 1.1e-05 25.8 12.4 6.1e-05 23.4 0.0 7.0 7 0 0 7 7 7 1 Domain of Unknown Function (DUF1081) Apolipoprotein PF01442.18 RUS82211.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SH2 PF00017.24 RUS82212.1 - 3.2e-21 75.2 0.1 6.4e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.17 RUS82212.1 - 8e-16 58.1 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RUS82212.1 - 8.9e-11 42.2 1.2 1.1e-09 38.7 0.7 2.6 2 1 0 2 2 2 1 PH domain SH3_1 PF00018.28 RUS82212.1 - 2e-10 40.1 0.1 4.8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS82212.1 - 2.3e-10 40.2 0.0 5.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 RUS82212.1 - 9.9e-09 34.9 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain BTK PF00779.19 RUS82212.1 - 1.1e-08 34.8 1.7 3.1e-08 33.3 1.7 1.8 1 0 0 1 1 1 1 BTK motif SH3_2 PF07653.17 RUS82212.1 - 7.2e-08 32.0 0.0 2.3e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 RUS82212.1 - 0.0019 18.4 1.9 0.0043 17.3 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_10 PF17902.1 RUS82212.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain RED_N PF07808.13 RUS82213.1 - 4.4e-95 317.7 15.0 4.4e-95 317.7 15.0 4.0 2 1 1 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.11 RUS82213.1 - 1.4e-53 180.1 4.2 1.4e-53 180.1 4.2 5.0 4 2 1 5 5 5 1 RED-like protein C-terminal region Lsm_interact PF05391.11 RUS82213.1 - 0.0049 16.3 0.2 0.021 14.3 0.2 2.2 1 0 0 1 1 1 1 Lsm interaction motif Abhydrolase_5 PF12695.7 RUS82214.1 - 2.6e-09 37.0 0.1 1.3e-08 34.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 RUS82214.1 - 0.0031 18.2 0.0 0.0047 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS82214.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3869 PF12985.7 RUS82214.1 - 0.034 14.5 0.3 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) Abhydrolase_5 PF12695.7 RUS82215.1 - 1.5e-19 70.3 1.0 2.5e-08 33.8 0.1 3.5 2 2 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 RUS82215.1 - 2.7e-08 34.7 0.1 0.0097 16.5 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS82215.1 - 0.00074 19.2 0.3 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 RUS82215.1 - 0.014 14.7 0.1 4.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) SGS PF05002.15 RUS82215.1 - 0.016 15.3 0.5 3.5 7.8 0.1 2.5 2 0 0 2 2 2 0 SGS domain OS-D PF03392.13 RUS82215.1 - 0.021 14.9 0.3 6.1 7.0 0.1 2.7 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Baculo_E66 PF04850.12 RUS82215.1 - 0.023 13.5 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Baculovirus E66 occlusion-derived virus envelope protein NleF_casp_inhib PF16809.5 RUS82215.1 - 0.032 14.1 0.3 12 5.7 0.1 3.0 2 1 0 2 2 2 0 NleF caspase inhibitor DUF2618 PF10940.8 RUS82215.1 - 0.059 13.2 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) DUF2647 PF10839.8 RUS82215.1 - 0.11 12.5 0.2 26 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) UQ_con PF00179.26 RUS82216.1 - 1.4e-14 53.9 0.0 1.8e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS82216.1 - 3.4e-05 23.5 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RUS82216.1 - 0.00095 19.4 0.0 0.0012 19.2 0.0 1.4 1 1 0 1 1 1 1 RWD domain Nore1-SARAH PF16517.5 RUS82216.1 - 0.17 11.8 0.3 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Rad50_zn_hook PF04423.14 RUS82217.1 - 2.3e-06 27.3 0.2 2.3e-06 27.3 0.2 6.2 5 0 0 5 5 5 1 Rad50 zinc hook motif DUF3800 PF12686.7 RUS82217.1 - 3e-05 24.6 1.6 2 9.1 0.9 5.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) SbcCD_C PF13558.6 RUS82217.1 - 7.3e-05 22.9 0.0 0.00029 21.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RUS82217.1 - 0.00035 21.1 9.6 0.00035 21.1 9.6 9.5 3 2 5 8 8 8 1 AAA domain AAA_15 PF13175.6 RUS82217.1 - 0.0018 18.1 14.4 0.0018 18.1 14.4 5.4 1 1 3 5 5 5 1 AAA ATPase domain BST2 PF16716.5 RUS82217.1 - 0.0031 18.1 7.0 0.0031 18.1 7.0 13.3 6 4 8 15 15 15 1 Bone marrow stromal antigen 2 Ubiq_cyt_C_chap PF03981.12 RUS82217.1 - 0.41 10.7 6.9 0.62 10.1 0.8 3.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Baculo_PEP_C PF04513.12 RUS82217.1 - 0.75 9.8 56.7 0.15 12.1 0.3 8.3 5 2 1 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF229 PF02995.17 RUS82218.1 - 7.9e-132 440.4 0.0 9.8e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS82218.1 - 2.4e-06 27.2 0.1 7.2e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Sulfatase DnaJ PF00226.31 RUS82219.1 - 2.3e-26 91.7 4.2 3.7e-26 91.0 4.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 RUS82219.1 - 2.9e-25 89.1 0.0 4.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 RUS82219.1 - 8.5e-12 45.3 17.3 8.5e-12 45.3 17.3 2.1 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 RUS82219.1 - 7.5 6.6 23.1 0.71 9.9 7.0 3.0 2 1 2 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Fibrinogen_C PF00147.18 RUS82220.1 - 1.5e-41 142.7 7.2 1.8e-41 142.4 7.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Neur_chan_LBD PF02931.23 RUS82221.1 - 2e-33 115.6 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 RUS82222.1 - 4e-31 108.2 0.0 5.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Ank_2 PF12796.7 RUS82223.1 - 9.2e-26 90.3 8.7 1.4e-10 41.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS82223.1 - 2.1e-18 66.4 2.6 5.2e-08 33.3 0.2 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS82223.1 - 2.8e-16 59.2 3.7 0.0022 18.3 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RUS82223.1 - 2.7e-15 54.9 0.4 0.053 14.1 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS82223.1 - 3.1e-14 52.8 0.8 2.7e-05 24.4 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) FERM_f0 PF16511.5 RUS82223.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM CENP-Q PF13094.6 RUS82224.1 - 0.18 12.0 6.9 0.63 10.2 6.9 1.9 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4770 PF15994.5 RUS82224.1 - 0.26 11.5 0.0 0.26 11.5 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4770) DUF3287 PF11690.8 RUS82224.1 - 2.4 7.9 7.8 18 5.0 7.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF4337 PF14235.6 RUS82224.1 - 5.9 7.0 7.4 18 5.4 7.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SAM_1 PF00536.30 RUS82225.1 - 2.4e-16 59.9 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS82225.1 - 2.3e-10 40.4 0.0 3.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras PF00071.22 RUS82226.1 - 2.5e-38 131.2 0.0 3.2e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS82226.1 - 1.9e-32 112.0 0.0 3.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS82226.1 - 1.3e-11 44.3 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS82226.1 - 1.2e-07 31.4 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS82226.1 - 1.3e-06 28.1 0.0 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS82226.1 - 4e-05 23.7 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS82226.1 - 0.0035 16.8 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 RUS82226.1 - 0.0036 17.3 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TniB PF05621.11 RUS82226.1 - 0.057 12.8 0.0 0.51 9.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 RUS82226.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RUS82226.1 - 0.2 12.1 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Radical_SAM PF04055.21 RUS82227.1 - 1.6e-30 106.7 0.2 6.9e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 RUS82227.1 - 1.9e-28 98.4 0.2 3.8e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 RUS82227.1 - 1.7e-06 27.9 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Fibrinogen_C PF00147.18 RUS82228.1 - 7.2e-28 97.9 0.4 1.5e-27 96.8 0.4 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS82228.1 - 1.6e-05 24.9 8.0 3.4e-05 23.8 8.0 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS82228.1 - 0.0016 18.5 8.0 0.0037 17.3 0.4 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1338 PF07063.13 RUS82228.1 - 0.017 14.3 0.4 0.029 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) DUF883 PF05957.13 RUS82228.1 - 0.23 12.1 4.6 1.4 9.6 0.9 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) IL11 PF07400.11 RUS82228.1 - 0.28 10.8 7.1 0.055 13.1 1.3 2.1 2 0 0 2 2 2 0 Interleukin 11 FAM184 PF15665.5 RUS82228.1 - 0.44 10.3 10.7 1.8 8.3 10.7 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Phasin PF05597.11 RUS82228.1 - 0.5 10.4 5.9 2.1 8.3 1.9 2.7 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HSBP1 PF06825.12 RUS82228.1 - 0.64 9.9 8.6 2.1 8.3 1.1 3.2 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF572 PF04502.13 RUS82228.1 - 0.96 9.0 8.8 1.7 8.2 8.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4164 PF13747.6 RUS82228.1 - 1.1 9.6 7.2 6.7 7.1 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) T3SS_needle_F PF09392.10 RUS82228.1 - 1.6 9.0 5.4 7.4 6.9 0.2 3.6 1 1 3 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HSCB_C PF07743.13 RUS82228.1 - 1.9 9.0 8.2 4.3 7.9 0.9 2.7 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 RUS82228.1 - 8.6 5.8 12.0 12 5.3 3.8 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Laminin_N PF00055.17 RUS82229.1 - 1.5e-74 250.5 0.0 1.5e-74 250.5 0.0 1.5 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 RUS82229.1 - 0.00024 21.2 12.0 0.00024 21.2 12.0 2.3 3 0 0 3 3 3 1 Laminin EGF domain F5_F8_type_C PF00754.25 RUS82229.1 - 0.00041 20.5 0.0 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain zf-C2H2_2 PF12756.7 RUS82230.1 - 3.8e-38 129.9 22.2 1.8e-19 69.9 5.3 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RUS82230.1 - 1e-09 38.4 24.8 0.051 14.4 0.8 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS82230.1 - 1.9e-06 28.0 29.0 0.017 15.6 1.7 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS82230.1 - 0.00026 21.2 17.7 0.022 15.1 2.6 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 RUS82230.1 - 0.0053 16.6 0.6 0.0053 16.6 0.6 3.1 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-Di19 PF05605.12 RUS82230.1 - 0.074 13.4 0.2 0.074 13.4 0.2 5.7 6 0 0 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 RUS82230.1 - 0.12 12.4 0.2 0.12 12.4 0.2 4.3 5 0 0 5 5 5 0 BED zinc finger TRAF6_Z2 PF18048.1 RUS82230.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.7 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Transpos_assoc PF13963.6 RUS82230.1 - 0.14 12.5 3.1 1.3 9.4 0.0 3.0 2 0 0 2 2 2 0 Transposase-associated domain zf-met PF12874.7 RUS82230.1 - 0.6 10.6 17.9 0.2 12.1 0.9 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RUS82230.1 - 1.9 8.3 13.5 3 7.7 1.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF4187 PF13821.6 RUS82230.1 - 5 7.0 11.5 27 4.6 0.1 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) zf-C2H2_6 PF13912.6 RUS82230.1 - 9.8 6.3 10.2 6.6 6.8 1.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Cpn60_TCP1 PF00118.24 RUS82233.1 - 7.3e-90 301.9 17.0 2.4e-89 300.2 17.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aminotran_1_2 PF00155.21 RUS82233.1 - 0.034 13.3 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II Cpn10 PF00166.21 RUS82234.1 - 1.4e-28 98.8 0.0 1.6e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Hexapep PF00132.24 RUS82234.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Mem_trans PF03547.18 RUS82235.1 - 3.4e-17 61.9 24.5 1.2e-11 43.7 5.3 3.0 3 1 1 4 4 4 2 Membrane transport protein DEP PF00610.21 RUS82235.1 - 2.7e-12 46.6 0.0 2.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Oxidored_q2 PF00420.24 RUS82235.1 - 0.37 10.4 5.1 0.14 11.8 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Saf_2TM PF18303.1 RUS82235.1 - 1 8.9 4.6 5.1 6.7 0.1 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain WH2 PF02205.20 RUS82236.1 - 2.1e-11 43.3 0.1 7.4e-11 41.5 0.1 2.1 1 0 0 1 1 1 1 WH2 motif GAS PF13851.6 RUS82237.1 - 0.00045 19.6 4.5 0.00045 19.6 4.5 3.2 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 RUS82237.1 - 0.0099 16.1 4.2 0.0099 16.1 4.2 3.5 3 1 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Pkinase PF00069.25 RUS82238.1 - 3.3e-63 213.5 0.0 4.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82238.1 - 3.9e-35 121.4 0.0 3.1e-33 115.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS82238.1 - 6.1e-05 22.0 0.0 9.5e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RUS82238.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 RUS82238.1 - 0.0071 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 RUS82238.1 - 0.029 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RUS82238.1 - 0.034 14.0 0.5 0.1 12.5 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 RUS82239.1 - 2.1e-23 82.8 0.0 3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82239.1 - 3e-13 49.9 0.0 5e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS82239.1 - 0.01 15.7 0.0 0.043 13.7 0.0 1.8 1 1 0 1 1 1 0 KR domain PAS_9 PF13426.7 RUS82240.1 - 1.8e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 1 0 1 1 1 1 PAS domain PAS_3 PF08447.12 RUS82240.1 - 0.00014 22.0 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 RUS82240.1 - 0.00054 19.9 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 RUS82240.1 - 0.00088 19.3 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold Nop14 PF04147.12 RUS82241.1 - 4.4e-06 25.3 37.2 5e-06 25.1 37.2 1.0 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 RUS82241.1 - 0.00025 19.6 42.7 0.0003 19.4 42.7 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 RUS82241.1 - 0.00059 19.4 42.8 0.00076 19.0 42.8 1.1 1 0 0 1 1 1 1 SDA1 Caldesmon PF02029.15 RUS82241.1 - 0.0011 17.9 37.5 0.0012 17.7 37.5 1.0 1 0 0 1 1 1 1 Caldesmon MDM1 PF15501.6 RUS82241.1 - 0.0012 18.1 22.6 0.0015 17.8 22.6 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 CCSAP PF15748.5 RUS82241.1 - 0.0012 19.1 21.2 0.0016 18.7 21.2 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated BUD22 PF09073.10 RUS82241.1 - 0.0031 16.9 35.4 0.0037 16.7 35.4 1.1 1 0 0 1 1 1 1 BUD22 DUF262 PF03235.14 RUS82241.1 - 0.015 15.5 5.4 0.016 15.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF966 PF06136.13 RUS82241.1 - 0.016 15.0 12.7 0.018 14.8 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RR_TM4-6 PF06459.12 RUS82241.1 - 0.034 14.0 31.4 0.042 13.7 31.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 RUS82241.1 - 0.036 13.9 19.0 0.047 13.5 19.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4045 PF13254.6 RUS82241.1 - 0.12 12.0 22.0 0.15 11.7 22.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 RUS82241.1 - 0.25 10.0 22.1 0.3 9.8 22.1 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 RUS82241.1 - 0.29 10.5 13.1 0.36 10.2 13.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Vfa1 PF08432.10 RUS82241.1 - 0.32 11.3 27.6 0.57 10.5 27.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 RUS82241.1 - 0.35 9.6 18.4 0.42 9.3 18.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5427 PF10310.9 RUS82241.1 - 0.4 9.6 26.9 0.51 9.2 26.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 RUS82241.1 - 0.5 9.1 19.4 0.59 8.9 19.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop53 PF07767.11 RUS82241.1 - 0.75 9.1 46.2 1.1 8.6 46.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.8 RUS82241.1 - 0.91 9.0 25.3 1.2 8.6 25.3 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Lin-8 PF03353.15 RUS82241.1 - 1.1 8.7 26.4 1.4 8.4 26.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 RUS82241.1 - 1.6 7.7 15.2 1.9 7.4 15.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 RUS82241.1 - 1.6 6.8 21.7 1.9 6.5 21.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 RUS82241.1 - 1.8 7.7 15.4 2.2 7.4 15.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 RUS82241.1 - 2.1 6.8 15.0 2.5 6.5 15.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 PIP5K PF01504.18 RUS82241.1 - 2.1 7.5 9.2 2.7 7.2 9.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SID-1_RNA_chan PF13965.6 RUS82241.1 - 2.3 6.5 7.6 2.5 6.4 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2151 PF10221.9 RUS82241.1 - 2.5 6.6 19.7 3 6.3 19.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CSRNP_N PF16019.5 RUS82241.1 - 2.6 7.9 12.2 3.3 7.6 12.2 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus AAA_11 PF13086.6 RUS82241.1 - 2.7 7.7 14.6 3.6 7.3 14.6 1.3 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.6 RUS82241.1 - 2.7 7.9 11.2 3.6 7.5 11.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 RUS82241.1 - 3 7.5 34.5 3.9 7.1 34.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LTV PF04180.14 RUS82241.1 - 5.5 6.6 29.5 6.8 6.3 29.5 1.1 1 0 0 1 1 1 0 Low temperature viability protein Bud13 PF09736.9 RUS82241.1 - 6.4 7.2 29.1 9.9 6.6 29.1 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex LAP1C PF05609.12 RUS82241.1 - 7 5.6 22.1 8.8 5.3 22.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3292 PF11696.8 RUS82241.1 - 7.5 4.8 13.1 8.9 4.5 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Gti1_Pac2 PF09729.9 RUS82241.1 - 8 6.5 13.3 11 6.1 13.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family PA26 PF04636.13 RUS82241.1 - 8.3 5.2 15.9 10 4.9 15.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) YL1 PF05764.13 RUS82241.1 - 8.7 6.4 49.8 12 5.9 49.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Sec62 PF03839.16 RUS82241.1 - 9.2 5.7 20.2 15 5.0 20.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RRN3 PF05327.11 RUS82241.1 - 9.6 4.6 30.8 13 4.2 30.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ELMO_CED12 PF04727.13 RUS82242.1 - 1.3e-40 139.4 0.1 2e-40 138.8 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Glyco_trans_2_3 PF13632.6 RUS82243.1 - 9.4e-30 104.0 0.1 9.4e-30 104.0 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RUS82243.1 - 1.4e-06 28.3 0.0 4.5e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CD225 PF04505.12 RUS82244.1 - 2.3e-17 62.9 2.9 5.5e-17 61.7 2.9 1.6 1 1 0 1 1 1 1 Interferon-induced transmembrane protein TauE PF01925.19 RUS82244.1 - 0.00044 20.0 0.6 0.00053 19.7 0.6 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4190 PF13828.6 RUS82244.1 - 0.0052 16.5 10.0 0.031 14.0 10.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Tetraspanin PF00335.20 RUS82244.1 - 0.016 14.9 1.4 0.016 14.9 1.4 1.7 2 0 0 2 2 2 0 Tetraspanin family Claudin_2 PF13903.6 RUS82244.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 RUS82244.1 - 0.027 14.7 4.2 0.063 13.6 4.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Cytochrom_C_asm PF01578.20 RUS82244.1 - 0.068 12.9 0.6 0.093 12.5 0.6 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein PMP22_Claudin PF00822.20 RUS82244.1 - 3.1 7.7 6.7 9.2 6.1 5.8 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Pex14_N PF04695.13 RUS82244.1 - 3.5 8.3 10.8 11 6.6 10.8 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Smr PF01713.21 RUS82245.1 - 5.7e-08 33.0 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Smr domain PI3K_1B_p101 PF10486.9 RUS82245.1 - 0.00046 18.1 0.7 0.0006 17.8 0.7 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIA PF03153.13 RUS82245.1 - 0.0058 16.7 6.4 0.011 15.7 6.4 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 RUS82245.1 - 0.018 14.6 7.7 0.032 13.8 7.7 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 RUS82245.1 - 0.066 11.4 10.1 0.099 10.8 10.1 1.3 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 RUS82245.1 - 0.1 12.9 10.7 0.21 11.8 10.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.16 RUS82245.1 - 0.3 10.3 3.3 0.55 9.4 3.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 RUS82245.1 - 0.46 10.3 7.9 0.16 11.9 4.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region RXT2_N PF08595.11 RUS82245.1 - 0.74 9.8 7.1 0.37 10.8 4.4 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal VEFS-Box PF09733.9 RUS82245.1 - 0.85 9.4 4.9 1.7 8.4 4.9 1.5 1 0 0 1 1 1 0 VEFS-Box of polycomb protein CDC45 PF02724.14 RUS82245.1 - 1.8 6.7 8.0 2.7 6.2 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 RUS82245.1 - 3.5 6.4 5.6 5.8 5.7 5.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 RUS82245.1 - 4.5 5.3 19.4 6.2 4.8 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi ABC_tran PF00005.27 RUS82246.1 - 1.9e-36 125.6 0.0 9.5e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS82246.1 - 1.9e-11 43.8 3.8 0.0018 17.7 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RUS82246.1 - 3.7e-09 36.8 7.3 0.24 11.2 1.4 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 RUS82246.1 - 1.5e-08 34.1 3.3 2.8e-08 33.2 3.3 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_16 PF13191.6 RUS82246.1 - 2.4e-06 28.1 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 RUS82246.1 - 5.6e-06 26.3 2.6 0.17 11.6 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 RUS82246.1 - 1.1e-05 25.9 0.0 0.03 14.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 RUS82246.1 - 2.4e-05 24.2 2.5 4.6e-05 23.3 2.5 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_22 PF13401.6 RUS82246.1 - 5.2e-05 23.5 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RUS82246.1 - 6.1e-05 23.0 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Fer4_21 PF14697.6 RUS82246.1 - 8.7e-05 22.6 1.5 0.00017 21.6 1.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 RUS82246.1 - 0.00031 20.7 0.0 0.14 12.1 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain Fer4_2 PF12797.7 RUS82246.1 - 0.00056 19.9 0.7 0.0012 18.8 0.7 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_29 PF13555.6 RUS82246.1 - 0.0006 19.5 0.4 1.2 8.9 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 RUS82246.1 - 0.00074 19.3 0.1 0.21 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS82246.1 - 0.00077 19.4 0.4 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.7 RUS82246.1 - 0.00078 20.0 0.2 0.0018 18.8 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 RUS82246.1 - 0.0011 19.1 0.2 0.0023 18.0 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RUS82246.1 - 0.0012 18.9 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 RUS82246.1 - 0.0015 18.7 0.0 0.46 10.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 RUS82246.1 - 0.0028 17.2 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RUS82246.1 - 0.0029 18.0 0.1 0.82 10.1 0.0 2.7 3 0 0 3 3 2 1 RNA helicase Fer4_16 PF13484.6 RUS82246.1 - 0.0038 18.1 0.3 0.012 16.6 0.3 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain SRP54 PF00448.22 RUS82246.1 - 0.004 16.8 4.3 0.1 12.2 0.1 2.6 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 RUS82246.1 - 0.0042 16.8 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS82246.1 - 0.0044 17.3 0.5 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 RUS82246.1 - 0.0048 16.9 0.0 0.07 13.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 RUS82246.1 - 0.0086 15.8 0.2 5.1 6.7 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase Fer4_17 PF13534.6 RUS82246.1 - 0.014 16.0 0.2 0.031 14.8 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 RUS82246.1 - 0.015 15.4 0.0 6.2 6.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 RUS82246.1 - 0.021 15.4 0.0 7.1 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 RUS82246.1 - 0.029 14.8 0.2 0.063 13.7 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 RUS82246.1 - 0.03 14.0 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 RUS82246.1 - 0.057 13.4 0.9 1.8 8.5 0.1 3.2 2 1 1 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 RUS82246.1 - 0.059 13.9 0.5 0.059 13.9 0.5 3.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RUS82246.1 - 0.063 12.5 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 RUS82246.1 - 0.085 13.1 0.0 27 5.1 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 RUS82246.1 - 0.099 12.7 0.5 22 5.1 0.0 3.1 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.13 RUS82246.1 - 0.15 11.2 0.1 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF853 PF05872.12 RUS82246.1 - 0.16 10.5 0.0 0.41 9.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MeaB PF03308.16 RUS82246.1 - 0.17 10.9 0.1 6.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RUS82246.1 - 0.28 11.4 0.8 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_4 PF12800.7 RUS82246.1 - 0.42 11.3 3.0 0.91 10.2 3.0 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain NTPase_1 PF03266.15 RUS82246.1 - 1.1 9.2 3.8 6.9 6.6 0.1 3.4 4 0 0 4 4 4 0 NTPase Peptidase_A2E PF12382.8 RUS82247.1 - 0.023 14.7 0.9 6.5 6.8 0.0 2.9 1 1 2 3 3 3 0 Retrotransposon peptidase BBIP10 PF14777.6 RUS82247.1 - 0.21 11.2 0.1 31 4.2 0.0 3.1 4 0 0 4 4 4 0 Cilia BBSome complex subunit 10 RNA_pol_Rpb1_R PF05001.13 RUS82247.1 - 3.8 8.1 11.4 34 5.0 1.8 3.6 3 0 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat HRCT1 PF15758.5 RUS82247.1 - 6.4 7.8 22.0 0.93 10.5 1.7 3.4 2 1 1 3 3 3 0 Histidine-rich carboxyl terminus protein 1 Lin-8 PF03353.15 RUS82248.1 - 0.86 9.1 8.1 1.2 8.6 8.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EGF_2 PF07974.13 RUS82249.1 - 0.00052 20.3 16.1 0.0013 19.1 16.1 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 RUS82249.1 - 0.026 14.6 10.8 0.059 13.4 10.8 1.6 1 0 0 1 1 1 0 Tenascin EGF domain DUF4453 PF14627.6 RUS82249.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Laminin_EGF PF00053.24 RUS82249.1 - 0.75 10.0 10.9 1.7 8.9 10.9 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 RUS82249.1 - 1.6 9.1 16.2 0.66 10.3 12.9 2.0 2 0 0 2 2 2 0 EGF-like domain Tox-GHH PF15636.6 RUS82250.1 - 7.2e-27 93.2 0.1 1.6e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 RUS82250.1 - 1e-17 64.2 126.8 7.3e-05 23.1 12.3 8.0 7 0 0 7 7 7 7 EGF-like domain RHS_repeat PF05593.14 RUS82250.1 - 9.1e-15 54.8 4.0 0.00024 21.5 2.1 6.1 5 0 0 5 5 5 2 RHS Repeat CarboxypepD_reg PF13620.6 RUS82250.1 - 7.9e-05 22.9 0.1 0.0004 20.6 0.1 2.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain NHL PF01436.21 RUS82250.1 - 0.00019 21.3 1.5 1.5 9.0 0.0 5.4 5 0 0 5 5 5 2 NHL repeat EGF PF00008.27 RUS82250.1 - 0.0039 17.5 9.2 0.0039 17.5 9.2 7.7 7 0 0 7 7 7 4 EGF-like domain CarbopepD_reg_2 PF13715.6 RUS82250.1 - 0.037 14.0 0.5 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 CarboxypepD_reg-like domain SH3_9 PF14604.6 RUS82252.1 - 1.3e-31 108.2 3.4 1.3e-10 41.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 RUS82252.1 - 8.5e-30 102.1 3.9 1e-11 44.2 0.1 3.7 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 RUS82252.1 - 4e-26 90.5 0.4 4.9e-09 35.7 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 RUS82252.1 - 6.4 7.1 11.3 8.2 6.8 0.6 3.7 4 0 0 4 4 4 0 Bacterial SH3 domain DAGK_cat PF00781.24 RUS82254.1 - 1.4e-22 79.7 0.2 2.6e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 RUS82254.1 - 3.9e-11 42.4 0.4 7.2e-11 41.5 0.0 1.5 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 NAD_kinase PF01513.21 RUS82254.1 - 0.078 12.2 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP-NAD kinase LRR_6 PF13516.6 RUS82255.1 - 4e-19 67.0 14.6 1.4e-05 24.8 0.1 7.5 7 0 0 7 7 7 5 Leucine Rich repeat EF-hand_7 PF13499.6 RUS82255.1 - 2.9e-07 30.9 1.6 7.4e-07 29.5 1.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 RUS82255.1 - 2.8e-05 24.4 21.2 0.035 14.6 0.9 4.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 RUS82255.1 - 5.7e-05 22.9 0.9 0.00012 21.9 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS82255.1 - 0.0002 21.0 3.6 0.029 14.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RUS82255.1 - 0.00023 20.5 4.8 0.0011 18.3 0.4 2.6 2 0 0 2 2 2 1 EF hand LRR_1 PF00560.33 RUS82255.1 - 0.0066 16.8 13.1 7.6 7.5 0.1 6.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_2 PF07723.13 RUS82255.1 - 0.032 14.9 0.0 7.4 7.4 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 RUS82255.1 - 0.047 13.5 21.5 0.5 10.2 2.0 5.1 3 2 2 5 5 5 0 Leucine rich repeat EF-hand_5 PF13202.6 RUS82255.1 - 0.078 12.5 0.4 0.078 12.5 0.4 2.4 2 0 0 2 2 2 0 EF hand DUF4362 PF14275.6 RUS82255.1 - 0.11 12.7 1.2 2.6 8.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4362) CENP-U PF13097.6 RUS82256.1 - 0.028 14.4 1.9 0.045 13.7 1.9 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit EphA2_TM PF14575.6 RUS82257.1 - 0.0017 19.2 2.4 0.036 15.0 0.0 4.0 3 1 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 RUS82257.1 - 0.0034 17.6 0.0 0.0034 17.6 0.0 7.2 4 2 2 6 6 6 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ETRAMP PF09716.10 RUS82257.1 - 0.031 14.3 0.0 0.031 14.3 0.0 3.9 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Cadherin_C_2 PF16492.5 RUS82257.1 - 0.047 14.4 0.0 0.7 10.7 0.0 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Orthoreo_P10 PF07204.11 RUS82257.1 - 0.12 12.3 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 WBP-1 PF11669.8 RUS82257.1 - 2.4 8.9 4.1 1.8 9.3 0.1 2.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Sulfotransfer_2 PF03567.14 RUS82258.1 - 2.5e-14 53.8 0.2 3.6e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family TRAP_alpha PF03896.16 RUS82260.1 - 0.00071 18.9 26.6 0.021 14.0 4.8 2.3 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit DUF2052 PF09747.9 RUS82260.1 - 0.0053 16.9 36.2 0.49 10.5 30.9 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 RUS82260.1 - 0.022 13.7 10.0 0.58 9.1 8.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Radial_spoke PF04712.12 RUS82260.1 - 0.036 13.0 0.1 0.036 13.0 0.1 3.1 2 1 1 3 3 1 0 Radial spokehead-like protein DDHD PF02862.17 RUS82260.1 - 0.065 13.4 2.0 0.49 10.5 3.9 1.5 2 0 0 2 2 2 0 DDHD domain Wzy_C PF04932.15 RUS82260.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase SDA1 PF05285.12 RUS82260.1 - 0.15 11.4 61.7 0.28 10.6 33.8 2.0 2 0 0 2 2 2 0 SDA1 V_ATPase_I PF01496.19 RUS82260.1 - 0.33 8.8 0.0 0.33 8.8 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 RUS82260.1 - 0.86 10.0 16.7 1.4 9.4 12.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 RUS82260.1 - 0.92 7.8 13.4 8.5 4.6 12.6 2.2 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 RUS82260.1 - 1.1 8.7 20.8 0.27 10.7 15.9 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 RUS82260.1 - 1.4 10.0 0.0 1.4 10.0 0.0 3.1 2 2 0 2 2 1 0 Domain of unknown function (DUF4834) DNA_pol_phi PF04931.13 RUS82260.1 - 1.7 6.7 80.6 0.24 9.4 33.6 2.1 2 0 0 2 2 2 0 DNA polymerase phi GAGA_bind PF06217.12 RUS82260.1 - 2 8.6 8.1 2.8 8.2 8.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SspB PF04386.13 RUS82260.1 - 2.3 8.1 24.4 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Stringent starvation protein B PIP5K PF01504.18 RUS82260.1 - 6.1 6.0 8.6 49 3.0 9.4 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Sigma70_ner PF04546.13 RUS82260.1 - 9.2 6.1 49.2 0.026 14.4 16.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4820 PF16091.5 RUS82260.1 - 9.9 5.5 19.9 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) KH_1 PF00013.29 RUS82261.1 - 1.3e-43 146.7 9.0 5.7e-19 67.7 1.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RUS82261.1 - 9.1e-09 35.0 0.7 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RUS82261.1 - 0.00018 21.3 0.1 0.86 9.5 0.2 2.4 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 RUS82261.1 - 0.0014 18.6 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 RUS82261.1 - 0.009 16.1 1.4 2 8.6 0.2 2.4 2 0 0 2 2 2 2 NusA-like KH domain RRM_1 PF00076.22 RUS82262.1 - 1.9e-11 43.6 0.0 4.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Leu_zip PF15294.6 RUS82263.1 - 6.8e-101 337.4 27.7 7.7e-101 337.2 27.7 1.0 1 0 0 1 1 1 1 Leucine zipper KxDL PF10241.9 RUS82263.1 - 0.00099 19.3 1.6 0.00099 19.3 1.6 3.5 3 1 0 3 3 3 1 Uncharacterized conserved protein MscS_porin PF12795.7 RUS82263.1 - 0.011 15.3 13.0 0.011 15.3 13.0 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain MAD PF05557.13 RUS82263.1 - 0.067 11.5 29.8 0.0052 15.2 22.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein RBD PF02196.15 RUS82263.1 - 0.069 13.2 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF724 PF05266.14 RUS82263.1 - 0.31 10.8 21.4 0.74 9.6 12.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 RUS82263.1 - 0.46 9.8 13.8 1 8.6 10.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3135 PF11333.8 RUS82263.1 - 0.53 10.6 10.4 4.7 7.5 2.6 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3135) CAML PF14963.6 RUS82263.1 - 0.53 10.4 8.8 0.86 9.7 8.8 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand NAD_binding_4 PF07993.12 RUS82263.1 - 0.64 9.1 5.3 1.5 7.9 4.5 1.8 1 1 1 2 2 2 0 Male sterility protein DUF5475 PF17569.2 RUS82263.1 - 1.3 9.4 4.7 4 7.8 1.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5475) Lebercilin PF15619.6 RUS82263.1 - 2.7 7.6 30.6 0.23 11.1 10.8 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 RUS82263.1 - 3.3 6.5 23.5 0.36 9.7 10.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 RUS82263.1 - 4.7 5.6 5.3 7.5 4.9 5.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2703 PF10865.8 RUS82263.1 - 5.3 7.2 8.4 3.8 7.7 0.5 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF2703) GAS PF13851.6 RUS82263.1 - 9.4 5.5 29.8 2.9 7.2 5.0 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 RUS82264.1 - 0.038 14.2 1.0 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4363 PF14276.6 RUS82264.1 - 0.043 13.9 1.1 0.45 10.6 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) PI_PP_I PF18363.1 RUS82264.1 - 0.05 13.8 0.8 0.32 11.2 0.1 2.0 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain DivIC PF04977.15 RUS82264.1 - 0.067 13.0 5.0 0.073 12.8 0.5 2.4 3 0 0 3 3 3 0 Septum formation initiator Tup_N PF08581.10 RUS82264.1 - 0.17 12.2 2.0 9.2 6.6 0.1 2.5 2 1 0 2 2 2 0 Tup N-terminal DAGK_acc PF00609.19 RUS82265.1 - 5.2e-51 173.1 0.0 9.9e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RUS82265.1 - 2e-25 88.8 0.0 3.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RUS82265.1 - 6.5e-25 86.8 26.3 3e-13 49.4 6.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DAG_kinase_N PF14513.6 RUS82265.1 - 5.3e-24 85.3 1.1 5.1e-23 82.1 0.4 2.6 2 1 0 2 2 2 1 Diacylglycerol kinase N-terminus EF-hand_1 PF00036.32 RUS82265.1 - 1e-08 34.1 1.9 0.0024 17.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS82265.1 - 2.1e-07 31.3 0.3 4.4e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS82265.1 - 2.2e-06 26.9 1.1 0.0031 16.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS82265.1 - 4.1e-06 26.3 0.1 0.0067 16.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS82265.1 - 0.00031 20.5 0.1 0.21 11.5 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair DUF1508 PF07411.12 RUS82265.1 - 0.096 12.6 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) C1_2 PF03107.16 RUS82265.1 - 0.14 12.5 23.3 0.45 10.9 4.2 3.2 3 0 0 3 3 3 0 C1 domain NAD_Gly3P_dh_N PF01210.23 RUS82266.1 - 4.1e-47 160.1 0.4 6.4e-47 159.4 0.4 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 RUS82266.1 - 4.5e-42 143.7 0.4 9.2e-42 142.7 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 RUS82266.1 - 0.033 14.8 0.3 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RVT_1 PF00078.27 RUS82268.1 - 1.9e-43 148.6 0.7 3.6e-43 147.7 0.5 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM222A PF15258.6 RUS82269.1 - 1.3e-06 27.9 0.4 0.0059 15.8 0.1 2.1 1 1 1 2 2 2 2 Protein family of FAM222A Myc_target_1 PF15179.6 RUS82269.1 - 2.1e-05 24.5 4.3 7.1 6.5 0.2 4.5 1 1 4 5 5 5 4 Myc target protein 1 Drf_FH1 PF06346.12 RUS82269.1 - 2.5e-05 24.0 0.0 0.026 14.2 0.0 2.3 1 1 1 2 2 2 2 Formin Homology Region 1 TrbM PF07424.11 RUS82269.1 - 0.29 11.1 0.7 17 5.4 0.1 3.5 1 1 2 4 4 4 0 TrbM DGF-1_4 PF11024.8 RUS82269.1 - 9 7.2 10.5 38 5.2 0.1 4.1 2 1 3 5 5 5 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Amino_oxidase PF01593.24 RUS82270.1 - 5.2e-17 62.3 0.2 1.6e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS82270.1 - 1.4e-09 38.0 0.0 3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RUS82270.1 - 0.0069 15.6 0.2 0.034 13.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS82270.1 - 0.01 15.0 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 RUS82270.1 - 0.019 14.6 0.1 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 RUS82270.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 RUS82270.1 - 0.059 11.8 0.0 0.086 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 RUS82270.1 - 0.075 11.7 0.1 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 RUS82271.1 - 8.2e-14 51.7 0.5 2.1e-12 47.1 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS82271.1 - 3.2e-12 46.5 0.0 9.1e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RUS82271.1 - 0.0014 17.9 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 RUS82271.1 - 0.0044 16.3 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RUS82271.1 - 0.0075 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 RUS82271.1 - 0.036 12.5 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 RUS82271.1 - 0.05 12.3 0.0 0.092 11.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 RUS82271.1 - 0.058 13.9 0.0 0.25 11.9 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS82271.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 RUS82271.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 RUS82271.1 - 0.22 10.8 0.0 0.55 9.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ribosomal_L50 PF10501.9 RUS82272.1 - 5.6e-08 32.9 0.1 8.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S TetR_C_6 PF13977.6 RUS82272.1 - 0.031 14.5 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal SNARE_assoc PF09335.11 RUS82273.1 - 2.8e-08 34.3 0.0 1.4e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 SNARE associated Golgi protein SAP PF02037.27 RUS82273.1 - 3.7e-07 29.7 0.0 6.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain CbiX PF01903.17 RUS82273.1 - 0.063 13.6 0.1 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 CbiX FAM199X PF15814.5 RUS82273.1 - 0.28 10.2 4.8 0.45 9.5 4.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X Baculo_11_kDa PF06143.11 RUS82273.1 - 0.39 10.3 1.9 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family Reticulon PF02453.17 RUS82273.1 - 2.5 8.1 8.6 3.4 7.6 0.5 3.2 3 0 0 3 3 3 0 Reticulon Septin PF00735.18 RUS82274.1 - 1.2e-94 316.8 1.2 1.5e-66 224.6 0.1 2.2 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 RUS82274.1 - 1.9e-08 34.3 0.0 4.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS82274.1 - 7.7e-07 29.2 4.2 1.5e-05 25.0 0.1 2.9 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 RUS82274.1 - 8.2e-07 28.8 1.7 4.8e-06 26.2 0.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 RUS82274.1 - 1.3e-05 24.9 0.0 3.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 RUS82274.1 - 4.1e-05 23.0 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 RUS82274.1 - 4.1e-05 23.7 6.6 0.27 11.3 0.2 3.4 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 RUS82274.1 - 5.1e-05 23.9 0.1 8.6e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 RUS82274.1 - 0.00015 22.0 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 RUS82274.1 - 0.0009 18.7 0.3 0.0023 17.4 0.3 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 RUS82274.1 - 0.0019 18.0 0.0 0.0037 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 RUS82274.1 - 0.0023 18.4 0.1 0.007 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS82274.1 - 0.0027 18.0 0.5 0.017 15.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RUS82274.1 - 0.0035 16.9 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RUS82274.1 - 0.0065 15.8 1.6 0.083 12.2 0.0 2.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family STAT2_C PF12188.8 RUS82274.1 - 0.0088 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Signal transducer and activator of transcription 2 C terminal ABC_tran PF00005.27 RUS82274.1 - 0.01 16.3 0.1 0.01 16.3 0.1 2.3 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 RUS82274.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 RUS82274.1 - 0.024 14.2 0.5 0.075 12.5 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.22 RUS82274.1 - 0.049 14.0 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 RUS82274.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Spc7 PF08317.11 RUS82274.1 - 0.79 8.5 9.4 2.3 7.0 5.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 RUS82274.1 - 8.5 6.8 9.9 0.69 10.3 3.9 2.4 2 1 1 3 3 3 0 Csm1 N-terminal domain FlxA PF14282.6 RUS82274.1 - 8.6 6.4 14.8 0.22 11.5 7.6 2.0 2 1 0 2 2 2 0 FlxA-like protein ADH_zinc_N PF00107.26 RUS82276.1 - 2.5e-23 82.5 1.3 4.2e-23 81.8 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS82276.1 - 2.2e-12 48.2 0.0 3.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS82276.1 - 1.1e-11 44.6 0.0 5.1e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 RUS82276.1 - 0.027 14.2 1.1 0.086 12.5 0.5 1.9 1 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CBM39 PF15886.5 RUS82276.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Aldo_ket_red PF00248.21 RUS82277.1 - 1.2e-43 149.4 0.0 1.3e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 RUS82278.1 - 2.9e-60 204.0 0.0 4.8e-60 203.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Med31 PF05669.12 RUS82279.1 - 2.1e-38 130.2 10.9 3.3e-38 129.6 10.9 1.3 1 0 0 1 1 1 1 SOH1 DUF3425 PF11905.8 RUS82279.1 - 0.049 13.6 1.1 0.51 10.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) INTS2 PF14750.6 RUS82280.1 - 0 1281.2 27.6 0 1281.0 27.6 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 DER1 PF04511.15 RUS82281.1 - 2e-73 246.4 15.5 2.3e-73 246.2 15.5 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 RUS82281.1 - 0.0079 15.9 2.1 0.01 15.6 0.0 2.0 1 1 1 2 2 2 1 Oleosin Peptidase_M10 PF00413.24 RUS82282.1 - 6e-58 195.2 0.0 9.9e-58 194.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 RUS82282.1 - 1.2e-23 82.8 13.1 5.7e-07 29.4 0.6 4.7 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 RUS82282.1 - 1.3e-07 31.7 0.1 2.4e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 RUS82282.1 - 5.2e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 RUS82282.1 - 0.0028 17.3 0.7 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 RUS82282.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 RUS82282.1 - 0.036 13.3 0.2 0.08 12.1 0.2 1.5 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 RUS82282.1 - 0.041 13.5 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like YadA_head PF05658.14 RUS82283.1 - 8.2e-14 51.6 8.0 0.014 15.7 0.1 4.9 3 2 0 4 4 4 4 Head domain of trimeric autotransporter adhesin DUF3265 PF11665.8 RUS82283.1 - 0.26 11.5 4.2 2.4e+02 2.1 0.0 6.2 4 3 5 10 10 10 0 Protein of unknown function (DUF3265) Semenogelin PF05474.11 RUS82283.1 - 1.3 7.4 4.3 1.5 7.3 4.3 1.0 1 0 0 1 1 1 0 Semenogelin DUF1676 PF07898.13 RUS82284.1 - 0.00011 22.3 0.5 0.00011 22.3 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) S_4TM PF18159.1 RUS82284.1 - 0.035 13.4 0.8 0.046 13.0 0.8 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain BUD22 PF09073.10 RUS82284.1 - 0.057 12.8 30.7 0.031 13.6 17.1 2.1 2 0 0 2 2 2 0 BUD22 DUF5412 PF17428.2 RUS82284.1 - 0.69 9.8 3.2 1.1 9.2 3.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5412) AMP-binding PF00501.28 RUS82285.1 - 8.3e-94 314.6 0.0 1e-93 314.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS82285.1 - 5e-19 69.1 1.3 1.1e-18 68.0 0.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF229 PF02995.17 RUS82286.1 - 6.3e-44 150.4 1.5 6.9e-44 150.3 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RUS82286.1 - 0.0039 16.8 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 RUS82287.1 - 9.6e-34 116.8 0.0 1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DERM PF14704.6 RUS82288.1 - 1.5e-47 161.9 0.2 1.8e-47 161.6 0.2 1.0 1 0 0 1 1 1 1 Dermatopontin Abhydrolase_1 PF00561.20 RUS82289.1 - 2.1e-27 96.4 0.0 9.2e-26 91.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS82289.1 - 3.2e-24 86.8 0.0 4.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS82289.1 - 7.2e-20 71.3 0.0 7e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 UPF0227 PF05728.12 RUS82289.1 - 7e-05 22.9 0.7 0.0011 19.0 0.3 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Lipase PF00151.19 RUS82289.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.3 1 1 0 1 1 1 1 Lipase Esterase PF00756.20 RUS82289.1 - 0.0021 17.7 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF1100 PF06500.11 RUS82289.1 - 0.0023 16.8 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Ser_hydrolase PF06821.13 RUS82289.1 - 0.0023 17.8 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase Palm_thioest PF02089.15 RUS82289.1 - 0.0097 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DLH PF01738.18 RUS82289.1 - 0.015 14.8 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 RUS82289.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 RUS82289.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.7 2 0 0 2 2 1 0 Lipase (class 3) BAAT_C PF08840.11 RUS82289.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 RUS82289.1 - 0.026 14.3 0.0 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 RUS82289.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Esterase_phd PF10503.9 RUS82289.1 - 0.097 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase PGAP1 PF07819.13 RUS82289.1 - 0.11 12.2 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein nos_propeller_2 PF18793.1 RUS82289.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 Pyr_redox_2 PF07992.14 RUS82289.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PH_3 PF14593.6 RUS82290.1 - 0.00028 21.0 0.6 30 4.8 0.0 5.3 3 1 2 6 6 6 3 PH domain Tachylectin PF14517.6 RUS82290.1 - 0.00057 19.5 5.3 0.23 11.0 0.5 4.3 2 1 3 5 5 5 3 Tachylectin EF-hand_1 PF00036.32 RUS82291.1 - 1.4e-11 43.0 0.3 0.012 15.1 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RUS82291.1 - 2.2e-11 44.0 1.1 2.6e-07 31.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS82291.1 - 2.7e-10 39.3 0.1 0.049 13.6 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS82291.1 - 3.5e-08 33.2 1.5 0.036 13.9 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain pair DUSP PF06337.12 RUS82291.1 - 3.7e-05 24.3 0.0 7.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 DUSP domain EF-hand_5 PF13202.6 RUS82291.1 - 0.0057 16.1 0.5 10 5.8 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF4088 PF13317.6 RUS82291.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) MFS_1 PF07690.16 RUS82292.1 - 1.6e-07 30.6 2.4 1.8e-07 30.4 2.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4203 PF13886.6 RUS82292.1 - 0.25 11.0 9.4 0.36 10.4 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) LPMO_10 PF03067.15 RUS82293.1 - 8.3e-20 72.3 0.0 1.2e-19 71.8 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading EGF_CA PF07645.15 RUS82294.1 - 2.7e-10 40.3 5.1 2.7e-10 40.3 5.1 3.6 4 1 0 4 4 4 1 Calcium-binding EGF domain Laminin_EGF PF00053.24 RUS82294.1 - 1.1e-05 25.5 7.3 1.1e-05 25.5 7.3 4.0 1 1 2 3 3 3 1 Laminin EGF domain EGF PF00008.27 RUS82294.1 - 0.00059 20.1 1.3 0.00059 20.1 1.3 4.9 4 2 0 4 4 4 2 EGF-like domain DNA_pol_phi PF04931.13 RUS82294.1 - 0.0088 14.2 51.4 0.012 13.8 51.4 1.2 1 0 0 1 1 1 1 DNA polymerase phi EGF_3 PF12947.7 RUS82294.1 - 0.017 15.3 2.3 0.017 15.3 2.3 4.4 3 3 0 3 3 3 0 EGF domain hEGF PF12661.7 RUS82294.1 - 0.098 13.3 2.3 0.098 13.3 2.3 6.0 5 1 0 5 5 5 0 Human growth factor-like EGF SDA1 PF05285.12 RUS82294.1 - 0.14 11.5 36.9 0.17 11.3 36.9 1.0 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 RUS82294.1 - 0.18 10.6 6.2 0.18 10.5 6.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS82294.1 - 0.44 8.7 38.7 0.58 8.3 38.7 1.1 1 0 0 1 1 1 0 Nop14-like family LapD_MoxY_N PF16448.5 RUS82296.1 - 0.0012 18.7 0.9 4.5 7.2 0.1 3.2 1 1 4 5 5 5 3 LapD/MoxY periplasmic domain Haem_degrading PF03928.14 RUS82296.1 - 0.03 14.4 9.3 2.6 8.1 0.2 3.7 1 1 2 3 3 3 0 Haem-degrading SAPS PF04499.15 RUS82296.1 - 0.08 11.7 8.2 0.081 11.7 8.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA_Me_trans PF03054.16 RUS82296.1 - 0.2 10.4 1.7 6.7 5.4 0.1 2.4 1 1 3 4 4 4 0 tRNA methyl transferase Lant_dehydr_C PF14028.6 RUS82296.1 - 0.22 11.0 9.0 11 5.5 0.1 3.7 1 1 5 6 6 6 0 Lantibiotic biosynthesis dehydratase C-term SDA1 PF05285.12 RUS82296.1 - 0.73 9.2 50.3 1.2 8.5 50.3 1.3 1 0 0 1 1 1 0 SDA1 REJ PF02010.15 RUS82297.1 - 7.3e-16 58.0 0.1 1.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 REJ domain SspB PF04386.13 RUS82297.1 - 0.0004 20.3 2.6 0.0004 20.3 2.6 2.1 1 1 1 2 2 1 1 Stringent starvation protein B SID-1_RNA_chan PF13965.6 RUS82297.1 - 0.0023 16.4 10.7 0.0029 16.1 10.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SRP-alpha_N PF04086.13 RUS82297.1 - 0.0052 16.8 25.6 0.0065 16.4 25.6 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 RUS82297.1 - 0.017 14.4 16.8 0.02 14.1 16.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF789 PF05623.12 RUS82297.1 - 0.018 14.7 11.2 0.025 14.2 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) CLN3 PF02487.17 RUS82297.1 - 0.02 14.0 8.5 0.027 13.5 8.5 1.2 1 0 0 1 1 1 0 CLN3 protein V_ATPase_I PF01496.19 RUS82297.1 - 0.03 12.3 13.5 0.037 12.0 13.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 RUS82297.1 - 0.037 13.1 22.8 0.048 12.7 22.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 U79_P34 PF03064.16 RUS82297.1 - 0.14 11.5 25.2 0.22 10.9 25.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 LicD PF04991.13 RUS82297.1 - 0.25 11.5 21.7 0.3 11.2 21.7 1.2 1 0 0 1 1 1 0 LicD family DUF2126 PF09899.9 RUS82297.1 - 0.3 9.1 5.5 0.42 8.6 5.5 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PTPRCAP PF15713.5 RUS82297.1 - 0.31 11.3 10.2 0.47 10.7 10.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NARP1 PF12569.8 RUS82297.1 - 0.32 9.9 30.4 0.49 9.2 30.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 STT3 PF02516.14 RUS82297.1 - 0.92 8.4 4.0 1.7 7.5 4.0 1.5 1 1 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Rtf2 PF04641.12 RUS82297.1 - 1.4 8.2 35.9 2.2 7.6 35.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PA26 PF04636.13 RUS82297.1 - 1.5 7.6 13.4 2.2 7.1 13.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 RUS82297.1 - 1.6 6.8 14.7 2 6.5 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 RUS82297.1 - 2.2 7.2 11.2 3 6.7 11.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FGF-BP1 PF06473.12 RUS82297.1 - 3.4 7.5 31.3 6 6.6 31.3 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Neur_chan_memb PF02932.16 RUS82297.1 - 4.8 7.2 15.9 6.4 6.8 15.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3959 PF13105.6 RUS82297.1 - 7.5 6.0 16.8 12 5.3 16.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Somatomedin_B PF01033.17 RUS82298.1 - 0.00013 22.3 9.5 0.00013 22.3 9.5 2.1 2 0 0 2 2 2 1 Somatomedin B domain Radial_spoke PF04712.12 RUS82298.1 - 1.8 7.4 12.3 2.8 6.8 12.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein FMO-like PF00743.19 RUS82299.1 - 1.9e-18 66.2 0.0 2e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FMO-like PF00743.19 RUS82300.1 - 8.4e-19 67.4 0.0 9.1e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 RUS82300.1 - 1.9e-06 28.0 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RUS82300.1 - 0.00071 18.9 0.0 0.00071 18.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RUS82300.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 RUS82300.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 RUS82300.1 - 0.088 12.0 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS82300.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding COesterase PF00135.28 RUS82301.1 - 3.1e-31 108.8 0.0 3.4e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 RUS82302.1 - 2.7e-73 247.6 0.0 3.3e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family RNA_pol_Rpb1_1 PF04997.12 RUS82303.1 - 2.7e-106 355.5 0.3 4.7e-106 354.6 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 RUS82303.1 - 1.4e-101 339.4 0.1 2.4e-101 338.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RUS82303.1 - 2.3e-74 249.1 0.1 5.2e-74 248.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 RUS82303.1 - 2.1e-66 223.4 0.5 5.4e-66 222.1 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 RUS82303.1 - 4e-53 179.0 3.6 4e-53 179.0 3.6 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 RUS82303.1 - 1.9e-49 167.6 0.0 3.6e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RUS82303.1 - 3.3e-39 133.2 1.7 7.5e-39 132.0 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 RUS82303.1 - 1.4e-07 31.5 542.3 0.036 14.4 14.5 26.3 3 2 20 34 34 34 26 RNA polymerase Rpb1 C-terminal repeat AcetDehyd-dimer PF09290.11 RUS82303.1 - 0.12 12.5 0.0 0.89 9.7 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation GAT PF03127.14 RUS82303.1 - 0.13 12.6 0.1 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 GAT domain RhoGEF PF00621.20 RUS82304.1 - 4.6e-42 144.3 0.4 8e-42 143.5 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 RUS82304.1 - 4e-18 65.1 0.5 1.8e-10 40.6 0.3 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 RUS82304.1 - 1.9e-10 41.0 0.0 0.0012 19.2 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS82304.1 - 0.00033 21.0 0.0 0.55 10.7 0.0 3.4 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Poxvirus_B22R_N PF13169.6 RUS82304.1 - 0.06 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal Imm30 PF15565.6 RUS82304.1 - 0.14 12.3 1.7 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 30 PsiB PF06290.11 RUS82305.1 - 0.011 15.1 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) BPL_LplA_LipB PF03099.19 RUS82306.1 - 2.5e-10 40.4 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lectin_C PF00059.21 RUS82307.1 - 4.4e-12 46.7 0.4 6.9e-12 46.1 0.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain Na_H_Exchanger PF00999.21 RUS82308.1 - 2.4e-78 263.6 30.1 1.4e-77 261.1 30.1 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 RUS82308.1 - 0.23 11.9 5.0 1.4 9.3 1.0 2.9 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Cation_ATPase_N PF00690.26 RUS82309.1 - 7.9e-05 22.3 0.9 2.4 7.9 0.0 4.2 4 1 1 5 5 5 2 Cation transporter/ATPase, N-terminus Csm1_N PF18504.1 RUS82309.1 - 0.00048 20.4 0.0 4.1 7.8 0.0 4.0 4 0 0 4 4 4 1 Csm1 N-terminal domain HVSL PF09749.9 RUS82309.1 - 0.016 14.7 0.6 1.2 8.5 0.0 2.8 2 1 2 4 4 4 0 Uncharacterised conserved protein SHS2_Rpb7-N PF03876.17 RUS82309.1 - 0.042 14.2 1.0 1.6e+02 2.7 0.0 5.1 6 0 0 6 6 6 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF2846 PF11008.8 RUS82309.1 - 0.084 12.9 0.0 48 4.1 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2846) DUF3045 PF11243.8 RUS82309.1 - 0.089 13.0 4.3 22 5.3 0.1 4.3 3 1 3 6 6 6 0 Protein of unknown function (DUF3045) DUF63 PF01889.17 RUS82310.1 - 1.7 8.7 6.7 54 3.8 0.1 3.9 1 1 2 4 4 4 0 Membrane protein of unknown function DUF63 Ion_trans PF00520.31 RUS82312.1 - 2.7e-23 82.5 18.5 2.7e-23 82.5 18.5 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 RUS82312.1 - 4.6e-07 29.7 0.8 2e-06 27.7 0.8 2.2 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 RUS82312.1 - 9.6e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Lig_chan PF00060.26 RUS82312.1 - 0.0068 16.3 0.2 0.0068 16.3 0.2 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel DUF1082 PF06449.11 RUS82312.1 - 0.98 9.3 3.8 13 5.7 0.1 3.3 1 1 2 3 3 3 0 Mitochondrial domain of unknown function (DUF1082) Na_H_Exchanger PF00999.21 RUS82314.1 - 1.4e-23 83.4 10.5 1.8e-23 83.0 10.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GWT1 PF06423.12 RUS82314.1 - 0.44 10.7 5.0 0.21 11.7 2.5 1.6 2 0 0 2 2 2 0 GWT1 OPT PF03169.15 RUS82314.1 - 0.72 8.4 10.2 0.24 10.0 7.0 1.6 1 1 1 2 2 2 0 OPT oligopeptide transporter protein DHHC PF01529.20 RUS82314.1 - 8.5 6.5 10.1 5.9 7.0 2.7 2.4 1 1 1 2 2 2 0 DHHC palmitoyltransferase zf-H2C2_2 PF13465.6 RUS82315.1 - 3.5e-18 65.1 59.8 5.1e-08 33.0 4.2 8.0 9 0 0 9 9 8 5 Zinc-finger double domain Integrase_H2C2 PF17921.1 RUS82315.1 - 2.3e-15 56.4 1.6 2.2e-11 43.7 0.4 4.4 5 1 1 6 6 4 2 Integrase zinc binding domain zf-C2H2_4 PF13894.6 RUS82315.1 - 4e-15 55.2 50.8 0.0013 19.3 1.3 8.2 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS82315.1 - 2e-10 40.5 54.7 0.00017 21.8 0.4 7.8 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS82315.1 - 5.4e-07 29.5 37.8 0.0011 18.9 2.0 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2 PF09337.10 RUS82315.1 - 0.00011 22.4 1.7 0.0094 16.2 0.0 3.7 3 0 0 3 3 3 1 H2C2 zinc finger zf-met PF12874.7 RUS82315.1 - 0.0041 17.5 28.3 0.65 10.5 0.1 7.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS82315.1 - 0.0093 16.2 31.9 0.25 11.7 0.0 7.4 7 0 0 7 7 6 2 Zinc-finger double-stranded RNA-binding ANAPC_CDC26 PF10471.9 RUS82315.1 - 0.011 16.5 0.0 0.011 16.5 0.0 4.0 3 1 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 zf-C2H2_11 PF16622.5 RUS82315.1 - 0.02 14.7 0.4 0.02 14.7 0.4 5.3 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RUS82315.1 - 0.59 10.1 27.9 1.5 8.8 0.5 5.5 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 RUS82315.1 - 0.62 10.8 20.9 0.045 14.5 1.4 4.6 5 0 0 5 5 4 0 zinc-ribbon family Spt46 PF17734.1 RUS82315.1 - 2.7 7.7 6.8 12 5.6 2.2 2.5 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 zf-Di19 PF05605.12 RUS82315.1 - 3.9 7.9 21.1 0.35 11.2 0.8 5.0 2 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 RUS82315.1 - 7.2 6.8 28.0 4.5 7.5 0.3 6.8 7 0 0 7 7 7 0 Zinc ribbon domain Metallophos PF00149.28 RUS82316.1 - 4e-39 135.2 0.0 6.7e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 RUS82316.1 - 0.0027 17.1 0.1 0.004 16.5 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) DUF1647 PF07801.11 RUS82316.1 - 0.09 12.5 0.9 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) RNase_H PF00075.24 RUS82318.1 - 1.7e-07 31.5 0.4 1.7e-07 31.5 0.4 2.6 3 0 0 3 3 3 1 RNase H Nop14 PF04147.12 RUS82320.1 - 1.4e-07 30.2 23.4 1.4e-07 30.2 23.4 1.9 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 RUS82320.1 - 0.0054 16.2 36.2 0.0054 16.2 36.2 2.1 2 0 0 2 2 2 1 SDA1 NPBW PF15180.6 RUS82320.1 - 0.031 14.1 4.4 3.9 7.4 0.2 3.3 1 1 2 3 3 3 0 Neuropeptides B and W GNVR PF13807.6 RUS82320.1 - 0.52 10.3 2.2 7.7 6.5 0.1 2.7 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Gag_p10 PF02337.17 RUS82320.1 - 4.1 7.4 11.7 13 5.8 0.3 4.3 1 1 3 5 5 5 0 Retroviral GAG p10 protein FerI PF08151.12 RUS82321.1 - 0.00014 21.9 17.1 4.9 7.3 0.3 7.2 1 1 3 5 5 5 4 FerI (NUC094) domain Knl1_RWD_C PF18210.1 RUS82321.1 - 0.0011 19.4 3.7 0.62 10.6 0.9 3.3 1 1 2 3 3 3 3 Knl1 RWD C-terminal domain DUF4724 PF15852.5 RUS82321.1 - 0.0055 17.1 13.1 26 5.4 0.2 6.6 1 1 6 7 7 7 0 Domain of unknown function (DUF4724) DUF11 PF01345.18 RUS82321.1 - 0.029 14.7 0.2 5.2 7.4 0.2 3.4 1 1 0 1 1 1 0 Domain of unknown function DUF11 DcpS PF05652.12 RUS82321.1 - 0.055 14.3 19.8 31 5.5 0.8 6.6 1 1 6 7 7 7 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal LRR_3 PF07725.12 RUS82321.1 - 0.079 12.8 0.2 1.5e+02 2.5 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat 7TM_GPCR_Sri PF10327.9 RUS82321.1 - 0.26 10.4 19.1 0.095 11.9 3.6 2.8 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Sri YafO_toxin PF13957.6 RUS82321.1 - 0.64 10.1 5.6 32 4.6 0.8 4.0 1 1 2 3 3 3 0 Toxin YafO, type II toxin-antitoxin system CgtA PF06306.11 RUS82322.1 - 0.093 12.1 0.7 18 4.7 0.0 3.1 1 1 3 4 4 4 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) MUG113 PF13455.6 RUS82322.1 - 2.8 8.7 10.3 9.3 7.0 1.0 3.2 1 1 1 2 2 2 0 Meiotically up-regulated gene 113 MYO10_CC PF16735.5 RUS82322.1 - 9.4 6.4 10.6 23 5.2 0.1 4.5 3 1 3 6 6 6 0 Unconventional myosin-X coiled coil domain Keratin_B2_2 PF13885.6 RUS82323.1 - 8.4e-05 22.4 4.2 0.7 9.9 4.2 2.9 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 RUS82323.1 - 0.33 10.9 5.5 2.5 8.1 5.5 1.9 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein TRP_2 PF08344.11 RUS82324.1 - 4.6e-28 97.2 1.3 1e-27 96.1 1.3 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 RUS82324.1 - 3.1e-20 72.5 19.4 5.8e-20 71.6 18.9 1.7 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RUS82324.1 - 6e-10 39.6 2.2 1.8e-06 28.4 0.5 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS82324.1 - 2.1e-08 33.8 3.2 0.084 13.5 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeat Ank PF00023.30 RUS82324.1 - 1.2e-05 25.5 3.4 0.073 13.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS82324.1 - 9e-05 22.7 0.6 2.1 8.8 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS82324.1 - 0.00017 22.1 0.7 0.22 12.2 0.2 3.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) CUB PF00431.20 RUS82325.1 - 5.1e-26 91.2 0.0 6.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 CUB domain C1q PF00386.21 RUS82326.1 - 3.8e-23 82.1 0.0 5.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 RUS82326.1 - 4.4e-05 23.4 0.0 7.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain PA14 PF07691.12 RUS82326.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PPC PF04151.15 RUS82326.1 - 0.017 16.2 0.1 0.043 14.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain CDT1_C PF16679.5 RUS82326.1 - 0.097 13.1 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Tropomyosin PF00261.20 RUS82327.1 - 0.0019 17.6 15.2 0.0019 17.6 15.2 6.0 5 1 1 6 6 6 3 Tropomyosin Thioredoxin_7 PF13899.6 RUS82329.1 - 0.061 13.5 1.6 0.13 12.4 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin-like Pro_CA PF00484.19 RUS82329.1 - 5.3 7.3 10.5 0.61 10.4 4.9 2.2 2 1 1 3 3 3 0 Carbonic anhydrase UBX PF00789.20 RUS82330.1 - 2.7e-14 53.1 0.0 4.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain PKD_channel PF08016.12 RUS82331.1 - 5.3e-34 117.6 21.9 7.2e-34 117.2 21.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 RUS82331.1 - 0.00015 21.1 30.5 0.0003 20.1 30.5 1.5 1 1 0 1 1 1 1 Ion transport protein PLAT PF01477.23 RUS82332.1 - 7.2e-13 49.1 0.3 1.9e-12 47.8 0.3 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain Yip1 PF04893.17 RUS82332.1 - 0.091 12.5 3.2 0.54 9.9 0.1 3.0 4 0 0 4 4 4 0 Yip1 domain RR_TM4-6 PF06459.12 RUS82333.1 - 0.00028 20.8 20.8 0.00032 20.6 20.8 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 LicD PF04991.13 RUS82333.1 - 0.00037 20.7 16.3 0.00046 20.4 16.3 1.1 1 0 0 1 1 1 1 LicD family DUF3405 PF11885.8 RUS82333.1 - 0.0011 17.7 3.6 0.0011 17.7 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Vfa1 PF08432.10 RUS82333.1 - 0.0059 17.0 32.1 0.0078 16.6 32.1 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 RUS82333.1 - 0.0061 16.7 5.5 0.0067 16.6 5.5 1.2 1 0 0 1 1 1 1 DDHD domain CDC45 PF02724.14 RUS82333.1 - 0.0076 14.6 17.1 0.0085 14.4 17.1 1.0 1 0 0 1 1 1 1 CDC45-like protein RPN2_C PF18004.1 RUS82333.1 - 0.0088 16.0 32.7 0.012 15.6 32.7 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain YL1 PF05764.13 RUS82333.1 - 0.013 15.6 32.1 0.017 15.3 32.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF262 PF03235.14 RUS82333.1 - 0.016 15.3 7.4 0.02 15.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SLC12 PF03522.15 RUS82333.1 - 0.023 13.8 16.7 0.026 13.6 16.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 RUS82333.1 - 0.032 14.3 14.8 0.04 14.0 14.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Endostatin PF06482.11 RUS82333.1 - 0.035 13.6 6.4 0.042 13.3 6.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF5308 PF17233.2 RUS82333.1 - 0.035 14.3 2.0 0.044 14.0 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SRP-alpha_N PF04086.13 RUS82333.1 - 0.046 13.7 28.2 0.06 13.3 28.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SpoVR PF04293.13 RUS82333.1 - 0.047 12.4 8.9 0.054 12.2 8.9 1.1 1 0 0 1 1 1 0 SpoVR like protein Connexin PF00029.19 RUS82333.1 - 0.048 13.4 19.3 0.067 12.9 19.3 1.2 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 RUS82333.1 - 0.078 12.8 16.5 0.094 12.5 16.5 1.1 1 0 0 1 1 1 0 AAA domain FGF-BP1 PF06473.12 RUS82333.1 - 0.088 12.6 24.4 0.13 12.1 24.4 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Serinc PF03348.15 RUS82333.1 - 0.11 11.4 1.9 0.11 11.4 1.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) NPR3 PF03666.13 RUS82333.1 - 0.15 10.8 21.7 0.19 10.5 21.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 RUS82333.1 - 0.16 10.7 12.3 0.19 10.4 12.3 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 RUS82333.1 - 0.18 12.2 22.2 0.25 11.8 22.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 RUS82333.1 - 0.23 9.8 1.2 0.22 9.9 1.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 RUS82333.1 - 0.24 9.5 7.8 0.24 9.5 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4228 PF14009.6 RUS82333.1 - 0.26 11.7 12.7 0.33 11.3 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TERB2 PF15101.6 RUS82333.1 - 0.29 11.1 10.8 0.41 10.7 10.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RP-C_C PF11800.8 RUS82333.1 - 0.34 11.0 6.5 0.41 10.7 6.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CENP-N PF05238.13 RUS82333.1 - 0.37 10.0 17.7 0.47 9.7 17.7 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Rtf2 PF04641.12 RUS82333.1 - 0.39 10.0 33.7 0.61 9.4 33.7 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3807 PF12720.7 RUS82333.1 - 0.4 10.9 30.6 0.036 14.3 26.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.8 RUS82333.1 - 0.48 9.1 22.0 0.65 8.7 22.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNApol_Exo PF18136.1 RUS82333.1 - 0.51 9.4 10.0 0.92 8.6 10.0 1.5 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF2828 PF11443.8 RUS82333.1 - 0.51 8.4 24.2 0.64 8.0 24.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) LMBR1 PF04791.16 RUS82333.1 - 0.52 9.2 2.3 0.5 9.2 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.6 RUS82333.1 - 0.63 10.6 10.4 0.73 10.4 10.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TraV PF09676.10 RUS82333.1 - 0.65 11.0 14.1 1.3 10.1 14.1 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4770 PF15994.5 RUS82333.1 - 0.67 10.2 26.4 1.2 9.4 26.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ALMT PF11744.8 RUS82333.1 - 0.78 8.5 14.4 1 8.1 14.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 RUS82333.1 - 0.81 9.4 11.8 0.95 9.2 11.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2126 PF09899.9 RUS82333.1 - 0.83 7.7 9.4 1 7.4 9.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF913 PF06025.12 RUS82333.1 - 0.88 8.5 9.3 1 8.3 9.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cellulose_synt PF03552.14 RUS82333.1 - 1.4 7.3 9.8 1.6 7.1 9.8 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.16 RUS82333.1 - 1.4 8.9 10.8 1.7 8.6 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 RUS82333.1 - 1.5 8.2 21.5 1.9 7.8 21.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RPOL_N PF14700.6 RUS82333.1 - 1.6 8.0 22.5 2.1 7.6 22.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF4569 PF15133.6 RUS82333.1 - 1.6 8.3 12.9 2.3 7.9 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) IHABP4_N PF16174.5 RUS82333.1 - 1.9 9.1 32.8 2.9 8.5 32.8 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Gti1_Pac2 PF09729.9 RUS82333.1 - 2.3 8.3 19.9 3.6 7.6 19.9 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family FancD2 PF14631.6 RUS82333.1 - 2.3 5.5 20.1 2.7 5.3 20.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Hydin_ADK PF17213.3 RUS82333.1 - 2.5 8.4 7.9 3.5 7.9 7.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Membralin PF09746.9 RUS82333.1 - 2.6 7.0 11.1 3.2 6.7 11.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein MCM_bind PF09739.9 RUS82333.1 - 2.9 6.2 17.2 3.4 6.0 17.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zip PF02535.22 RUS82333.1 - 3.1 6.9 11.7 3.7 6.7 11.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 RUS82333.1 - 3.7 6.3 36.1 4.6 6.0 36.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.19 RUS82333.1 - 3.8 6.3 13.2 4.6 6.0 13.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF5427 PF10310.9 RUS82333.1 - 4.2 6.2 21.2 5.2 5.9 21.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPL5 PF18168.1 RUS82333.1 - 4.9 6.3 20.7 6.8 5.9 20.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 TMEM214 PF10151.9 RUS82333.1 - 4.9 5.5 29.0 6 5.2 29.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4614 PF15391.6 RUS82333.1 - 6.3 6.8 12.8 10 6.1 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pannexin_like PF12534.8 RUS82333.1 - 6.7 5.7 15.3 9.3 5.2 15.3 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AF-4 PF05110.13 RUS82333.1 - 7 4.6 33.5 7.8 4.4 33.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CSG2 PF16965.5 RUS82333.1 - 7.4 5.4 7.8 9.3 5.1 7.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MDFI PF15316.6 RUS82333.1 - 8.4 6.4 11.4 13 5.9 11.4 1.4 1 0 0 1 1 1 0 MyoD family inhibitor Folate_carrier PF01770.18 RUS82333.1 - 8.5 5.0 10.4 13 4.4 10.4 1.4 1 0 0 1 1 1 0 Reduced folate carrier Otopetrin PF03189.13 RUS82333.1 - 10 4.8 7.3 12 4.6 7.3 1.1 1 0 0 1 1 1 0 Otopetrin RT_RNaseH_2 PF17919.1 RUS82334.1 - 3.7e-34 116.7 0.0 7.4e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS82334.1 - 1.5e-33 115.2 0.0 2.9e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS82334.1 - 1.7e-18 66.9 0.1 3.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS82334.1 - 1.2e-14 54.2 0.1 2.7e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RUS82334.1 - 0.00015 21.9 0.0 0.00058 20.0 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DNA_pol_viral_C PF00336.18 RUS82334.1 - 0.001 18.5 0.0 0.0034 16.8 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase (viral) C-terminal domain Prefoldin_2 PF01920.20 RUS82336.1 - 5.2e-13 48.9 1.8 2.6e-12 46.6 1.8 1.8 1 1 0 1 1 1 1 Prefoldin subunit DUF1351 PF07083.11 RUS82336.1 - 0.0071 16.1 1.0 0.0092 15.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Fmp27 PF10344.9 RUS82336.1 - 0.026 12.7 0.8 0.033 12.3 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Resolvase PF00239.21 RUS82336.1 - 0.063 13.4 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain BHD_1 PF10403.9 RUS82339.1 - 0.0019 18.0 18.0 14 5.6 0.1 6.8 1 1 4 5 5 5 4 Rad4 beta-hairpin domain 1 BclA_C PF18573.1 RUS82339.1 - 2.8 7.9 8.2 12 5.8 0.2 3.0 1 1 3 4 4 4 0 BclA C-terminal domain DUF3324 PF11797.8 RUS82339.1 - 3.8 7.5 10.5 22 5.0 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function C-terminal (DUF3324) UPF0016 PF01169.19 RUS82340.1 - 0.19 12.1 7.2 6.9 7.1 1.3 3.3 1 1 1 2 2 2 0 Uncharacterized protein family UPF0016 Phage_holin_2_2 PF10746.9 RUS82340.1 - 0.52 10.0 8.3 30 4.4 0.1 4.3 1 1 4 5 5 5 0 Phage holin T7 family, holin superfamily II RPW8 PF05659.11 RUS82340.1 - 1 9.0 3.3 43 3.8 0.1 3.2 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Guanylate_kin PF00625.21 RUS82341.1 - 3.9e-48 163.5 0.6 1.1e-47 162.1 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 RUS82341.1 - 2.5e-23 81.9 4.0 8.5e-23 80.2 4.0 2.0 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SPX PF03105.19 RUS82341.1 - 4.6 7.1 20.9 0.31 10.9 2.4 2.2 2 0 0 2 2 2 0 SPX domain Spectrin PF00435.21 RUS82342.1 - 1.3e-44 151.0 65.7 4.3e-10 40.0 3.5 9.8 9 0 0 9 9 9 7 Spectrin repeat RhoGEF PF00621.20 RUS82342.1 - 1.7e-38 132.7 0.6 1.7e-38 132.7 0.6 4.7 5 2 1 6 6 5 1 RhoGEF domain CRAL_TRIO_2 PF13716.6 RUS82342.1 - 9.7e-08 32.3 0.0 8.5e-07 29.2 0.0 2.7 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 RUS82342.1 - 2.1e-05 24.3 0.0 8e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 RUS82342.1 - 5.7e-05 23.6 0.2 0.00032 21.2 0.2 2.4 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 RUS82342.1 - 0.0033 17.7 1.4 0.018 15.3 0.3 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 RUS82342.1 - 0.0052 16.7 1.1 0.02 14.8 0.2 2.5 2 0 0 2 2 2 1 PH domain SH3-RhoG_link PF16609.5 RUS82342.1 - 0.0071 16.1 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region SH3_1 PF00018.28 RUS82342.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 RUS82342.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Synaptobrevin PF00957.21 RUS82342.1 - 0.27 11.1 2.7 7.4 6.4 0.1 3.9 4 0 0 4 4 4 0 Synaptobrevin RhoGEF PF00621.20 RUS82343.1 - 1.7e-41 142.4 0.5 3.6e-41 141.4 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3-RhoG_link PF16609.5 RUS82343.1 - 0.00013 21.8 0.2 0.00013 21.8 0.2 2.0 3 0 0 3 3 3 1 SH3-RhoGEF linking unstructured region PH_10 PF15411.6 RUS82343.1 - 0.00019 21.7 0.5 0.00082 19.6 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Put_Phosphatase PF06888.12 RUS82343.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative Phosphatase TFIIA PF03153.13 RUS82343.1 - 1.4 8.9 25.6 2.1 8.3 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 RUS82343.1 - 2 8.5 20.3 1.1 9.4 6.2 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 RUS82344.1 - 6.2e-53 179.8 0.0 8.6e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82344.1 - 1.1e-21 77.3 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 RUS82344.1 - 4.1e-18 65.2 0.0 7.9e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS82344.1 - 1.3e-13 51.4 0.1 1.3e-13 51.4 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS82344.1 - 2.9e-11 43.4 0.0 6.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 RUS82344.1 - 6.4e-09 36.0 0.7 8.1e-07 29.3 0.0 2.7 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.6 RUS82344.1 - 7.1e-08 32.7 0.1 2.2e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS82344.1 - 4.9e-05 23.5 0.5 0.00061 19.9 0.5 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain SH3_1 PF00018.28 RUS82344.1 - 0.0042 16.7 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain TFIIA PF03153.13 RUS82344.1 - 0.16 11.9 15.2 0.25 11.3 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA_anti-codon PF01336.25 RUS82346.1 - 0.0092 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 RUS82346.1 - 0.026 14.2 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 CSN8_PSD8_EIF3K PF10075.9 RUS82347.1 - 2.2e-32 112.0 0.0 2.7e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 RUS82347.1 - 0.038 14.5 0.0 0.054 14.0 0.0 1.4 1 1 0 1 1 1 0 PCI domain Apolipoprotein PF01442.18 RUS82348.1 - 7.6e-14 52.0 23.5 5.9e-06 26.3 4.2 4.3 2 1 2 4 4 4 4 Apolipoprotein A1/A4/E domain Mucin-like PF16058.5 RUS82348.1 - 0.063 13.4 33.6 0.13 12.4 3.5 5.1 3 1 1 4 4 4 0 Mucin-like DUF883 PF05957.13 RUS82348.1 - 2.5 8.8 16.5 6.1 7.5 0.8 4.8 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Neur_chan_LBD PF02931.23 RUS82350.1 - 6.7e-47 159.7 0.6 9.3e-47 159.2 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS82350.1 - 2.4e-21 76.9 4.2 5.3e-21 75.8 4.2 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3675 PF12428.8 RUS82350.1 - 2.6 8.6 6.1 2.7 8.6 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Lamprin PF06403.11 RUS82351.1 - 1.4 8.9 8.1 25 4.8 4.3 3.0 1 1 1 2 2 2 0 Lamprin Vma12 PF11712.8 RUS82352.1 - 5.1e-24 84.9 0.0 7.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SIR2 PF02146.17 RUS82353.1 - 2e-51 174.4 0.0 3.1e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RUS82353.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain WD40 PF00400.32 RUS82354.1 - 2.1e-09 37.8 0.3 0.00012 22.8 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat MAR_sialic_bdg PF10564.9 RUS82354.1 - 0.044 13.8 0.3 0.082 13.0 0.3 1.4 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat DERM PF14704.6 RUS82355.1 - 1.7e-39 135.7 0.8 2.1e-39 135.4 0.8 1.0 1 0 0 1 1 1 1 Dermatopontin Antimicrobial_6 PF08036.11 RUS82355.1 - 0.16 12.1 0.2 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide Pkinase PF00069.25 RUS82356.1 - 1.7e-24 86.7 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82356.1 - 7.8e-14 51.6 0.0 9.9e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PAP2_3 PF14378.6 RUS82356.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily Kinase-like PF14531.6 RUS82356.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 RUS82357.1 - 1.3e-53 182.2 38.2 1.3e-51 175.6 29.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS82357.1 - 1.7e-11 43.6 29.4 1.7e-10 40.4 29.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4244 PF14029.6 RUS82357.1 - 0.13 11.7 0.5 0.45 10.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4244) MFS_2 PF13347.6 RUS82357.1 - 5.4 5.5 28.3 0.19 10.2 9.3 4.0 2 1 2 5 5 5 0 MFS/sugar transport protein RUN PF02759.19 RUS82358.1 - 1e-14 54.6 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 RUN domain PH_9 PF15410.6 RUS82360.1 - 2.1e-45 153.9 0.6 4.3e-45 152.9 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 RUS82360.1 - 7.8e-43 146.3 0.4 2.3e-42 144.7 0.4 1.8 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 RUS82360.1 - 1.7e-08 34.9 0.2 5.5e-08 33.3 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 RUS82360.1 - 0.15 12.4 0.2 0.34 11.3 0.2 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region AIF-MLS PF14962.6 RUS82360.1 - 0.67 9.9 4.8 0.21 11.5 1.1 2.1 2 0 0 2 2 2 0 Mitochondria Localisation Sequence PRAP PF15314.6 RUS82360.1 - 0.68 10.5 2.4 6.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Proline-rich acidic protein 1, pregnancy-specific uterine Sulfotransfer_1 PF00685.27 RUS82361.1 - 2.1e-30 106.1 0.0 3.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS82361.1 - 2.8e-16 60.5 0.0 4.3e-10 40.3 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Pentapeptide_4 PF13599.6 RUS82364.1 - 1.7e-05 24.9 0.0 0.017 15.3 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 RUS82364.1 - 0.00017 21.7 0.2 1.6 9.0 0.0 3.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 RUS82364.1 - 0.0039 16.8 0.0 3.6 7.3 0.0 3.2 2 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Nop14 PF04147.12 RUS82365.1 - 2.3e-05 22.9 28.2 2.5e-05 22.7 28.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS82365.1 - 0.00051 19.6 31.7 0.00058 19.4 31.7 1.1 1 0 0 1 1 1 1 SDA1 Phage_DNA_bind PF02303.17 RUS82365.1 - 0.0017 18.6 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Helix-destabilising protein Mpp10 PF04006.12 RUS82365.1 - 0.012 14.0 23.5 0.014 13.9 23.5 1.1 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 RUS82365.1 - 0.02 15.4 0.3 0.031 14.7 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 RUS82365.1 - 0.81 8.4 9.5 0.91 8.2 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 RUS82365.1 - 1.8 8.4 8.8 2.3 8.0 8.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 RUS82365.1 - 4.2 6.6 33.4 5.3 6.3 33.4 1.2 1 0 0 1 1 1 0 BUD22 Ig_3 PF13927.6 RUS82366.1 - 3.1e-18 66.1 0.1 4.9e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS82366.1 - 1.6e-17 63.3 0.1 8.4e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS82366.1 - 9.1e-15 54.6 0.2 6.4e-07 29.5 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS82366.1 - 3.7e-10 40.0 0.4 1.7e-06 28.2 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS82366.1 - 2.2e-09 37.5 0.0 0.00097 19.4 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 RUS82366.1 - 0.0039 17.4 0.0 6.3 7.1 0.0 3.3 2 1 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS82366.1 - 0.012 15.2 0.0 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 RUS82366.1 - 0.016 15.3 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Ank_2 PF12796.7 RUS82367.1 - 2.9e-70 232.8 11.8 4.4e-16 59.2 0.1 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS82367.1 - 6.1e-38 124.5 9.3 0.0019 18.5 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 RUS82367.1 - 2.6e-37 125.6 14.2 0.00016 22.0 0.0 10.4 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 RUS82367.1 - 7.1e-34 115.8 7.6 6.4e-12 45.7 0.0 8.9 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS82367.1 - 2.6e-28 97.7 15.0 6.1e-08 32.8 0.1 8.8 6 2 4 10 10 10 7 Ankyrin repeats (many copies) CARD_2 PF16739.5 RUS82367.1 - 1.1e-10 41.3 0.7 4.4e-10 39.4 0.3 2.2 2 0 0 2 2 2 1 Caspase recruitment domain SOCS_box PF07525.16 RUS82367.1 - 0.015 15.6 0.5 0.046 14.1 0.5 1.9 1 0 0 1 1 1 0 SOCS box NCD3G PF07562.14 RUS82368.1 - 1.8e-08 34.2 11.1 0.66 10.0 0.1 4.2 4 0 0 4 4 4 4 Nine Cysteines Domain of family 3 GPCR C1_4 PF07975.12 RUS82368.1 - 4.3e-06 26.9 1.3 10 6.4 0.0 4.4 4 0 0 4 4 4 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 RUS82368.1 - 0.00022 21.5 17.4 1.6 9.3 0.4 4.8 5 0 0 5 5 4 4 Zinc-finger double domain Ephrin_rec_like PF07699.13 RUS82368.1 - 0.00037 20.2 18.1 0.49 10.2 0.2 4.3 4 0 0 4 4 4 3 Putative ephrin-receptor like zinc_ribbon_10 PF10058.9 RUS82368.1 - 0.00043 19.9 2.4 8.9 6.1 0.0 4.3 4 0 0 4 4 4 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_4 PF13894.6 RUS82368.1 - 0.0025 18.5 22.0 3.5 8.7 0.6 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger TFIIS_C PF01096.18 RUS82368.1 - 0.0058 16.5 8.1 29 4.6 0.1 4.4 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 RUS82368.1 - 0.0072 16.2 17.9 0.7 9.8 4.2 4.9 1 1 4 5 5 5 2 SprT-like zinc ribbon domain Desulfoferrod_N PF06397.12 RUS82368.1 - 0.01 15.4 6.4 8.9 6.0 0.1 4.1 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 RUS82368.1 - 0.012 15.5 6.6 6.7 6.8 0.1 4.7 5 0 0 5 5 5 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 RUS82368.1 - 0.015 15.6 14.0 8.5 6.7 0.0 5.0 5 1 0 5 5 4 0 zinc-ribbon zf-C2H2_jaz PF12171.8 RUS82368.1 - 0.017 15.4 15.0 0.4 11.0 0.6 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RUS82368.1 - 0.022 14.4 11.1 4.6 6.9 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Tnp_zf-ribbon_2 PF13842.6 RUS82368.1 - 0.023 15.5 14.5 16 6.4 0.1 4.5 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.26 RUS82368.1 - 1.2 9.7 25.6 3 8.5 0.2 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type HalOD2 PF18547.1 RUS82368.1 - 3.2 7.7 6.5 61 3.6 0.1 3.8 4 0 0 4 4 4 0 Halobacterial output domain 2 Laminin_EGF PF00053.24 RUS82368.1 - 5.7 7.2 23.3 13 6.1 1.0 4.3 4 0 0 4 4 4 0 Laminin EGF domain Zn-ribbon_8 PF09723.10 RUS82368.1 - 6.4 7.0 20.7 16 5.7 0.4 4.4 4 0 0 4 4 4 0 Zinc ribbon domain MRG PF05712.13 RUS82369.1 - 1.8e-48 164.5 0.5 1.8e-48 164.5 0.5 2.3 2 1 0 2 2 1 1 MRG Tudor-knot PF11717.8 RUS82369.1 - 7.3e-14 51.4 0.9 2.4e-13 49.8 0.9 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF927 PF06048.11 RUS82369.1 - 0.002 17.8 1.4 0.0034 17.0 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF927) MMR1 PF08505.10 RUS82369.1 - 0.092 13.0 22.6 0.13 12.6 22.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein AF-4 PF05110.13 RUS82369.1 - 0.63 8.1 36.3 0.79 7.7 36.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ndc1_Nup PF09531.10 RUS82369.1 - 0.87 8.2 11.6 1.1 7.9 11.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 RUS82369.1 - 4.7 5.6 19.5 6.1 5.2 19.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.7 RUS82369.1 - 6.3 4.8 20.9 8.3 4.4 20.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 RUS82369.1 - 6.8 5.4 22.8 9 5.0 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Asp-B-Hydro_N PF05279.11 RUS82369.1 - 7.7 6.5 32.7 11 6.0 32.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 RUS82369.1 - 8.8 4.7 39.0 11 4.4 39.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HRM PF02793.22 RUS82370.1 - 1e-13 51.4 5.7 2e-13 50.4 5.7 1.5 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 RUS82370.1 - 1.8e-12 47.0 11.5 1.5e-09 37.5 0.5 2.9 2 1 1 3 3 3 2 7 transmembrane receptor (Secretin family) Staph_haemo PF05480.11 RUS82371.1 - 0.0026 17.5 4.3 27 4.7 0.1 6.6 4 2 3 8 8 8 1 Staphylococcus haemolytic protein DUF5008 PF16400.5 RUS82371.1 - 0.0059 16.7 1.0 55 3.9 0.0 4.9 1 1 4 7 7 7 0 Domain of unknown function (DUF5008) CelTOS PF18659.1 RUS82371.1 - 0.012 16.0 8.2 2.3 8.7 0.4 3.3 1 1 2 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites TEX33 PF15400.6 RUS82371.1 - 0.013 16.0 5.4 84 3.7 5.2 4.7 1 1 0 1 1 1 0 Testis-expressed sequence 33 protein family Radical_SAM PF04055.21 RUS82372.1 - 3e-24 86.3 0.0 6.9e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 RUS82372.1 - 7.6e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Fer4_12 PF13353.6 RUS82372.1 - 0.1 12.9 1.7 25 5.1 0.2 3.2 2 1 0 2 2 2 0 4Fe-4S single cluster domain PAN_2 PF08276.11 RUS82372.1 - 1.8 8.8 8.9 0.077 13.1 2.7 2.0 2 0 0 2 2 2 0 PAN-like domain His_Phos_1 PF00300.22 RUS82373.1 - 3.8e-07 30.0 0.0 4.2e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 RUS82374.1 - 2e-12 47.2 0.0 5.6e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Exo84_C PF16528.5 RUS82375.1 - 1.3e-52 178.6 0.4 6.2e-52 176.4 0.0 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 RUS82375.1 - 1e-15 57.5 0.7 1e-15 57.5 0.7 3.1 3 0 0 3 3 3 1 Vps51/Vps67 Uteroglobin PF01099.17 RUS82375.1 - 0.6 10.5 4.7 0.69 10.3 0.3 3.3 4 0 0 4 4 4 0 Uteroglobin family Fes1 PF08609.10 RUS82375.1 - 0.71 10.8 3.8 4.4 8.3 1.4 3.0 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Presenilin PF01080.17 RUS82375.1 - 2.3 6.9 7.4 4 6.1 7.4 1.3 1 0 0 1 1 1 0 Presenilin NAM-associated PF14303.6 RUS82375.1 - 5.4 7.7 17.5 15 6.3 17.5 1.7 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SH2 PF00017.24 RUS82376.1 - 7.8e-14 51.5 0.1 1.5e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Phe_ZIP PF08916.11 RUS82376.1 - 4.8e-12 46.4 3.0 1.2e-11 45.2 3.0 1.6 1 0 0 1 1 1 1 Phenylalanine zipper PH PF00169.29 RUS82376.1 - 1.3e-09 38.5 0.0 2.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Pro_dh PF01619.18 RUS82378.1 - 3.3e-85 286.2 1.7 5.4e-84 282.2 1.7 2.0 1 1 0 1 1 1 1 Proline dehydrogenase PPR_3 PF13812.6 RUS82378.1 - 0.016 15.2 0.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Dynein_C PF18199.1 RUS82379.1 - 2e-96 322.9 0.0 2.3e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RUS82380.1 - 1.1e-31 109.9 0.1 1.9e-31 109.1 0.1 1.3 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RUS82380.1 - 1.2e-24 86.7 0.1 1.7e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain MIX PF18529.1 RUS82380.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins AAA_9 PF12781.7 RUS82381.1 - 2.5e-58 196.8 2.8 3.6e-58 196.3 2.8 1.3 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 RUS82382.1 - 2.3e-17 63.0 0.4 2.6e-17 62.9 0.4 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor CEP63 PF17045.5 RUS82382.1 - 0.0079 16.1 1.2 0.013 15.5 1.2 1.4 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa MT PF12777.7 RUS82383.1 - 7e-07 28.6 2.4 7.8e-07 28.4 2.4 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Metal_resist PF13801.6 RUS82383.1 - 0.73 10.0 5.5 0.98 9.6 5.5 1.2 1 0 0 1 1 1 0 Heavy-metal resistance AAA_8 PF12780.7 RUS82385.1 - 2.2e-56 191.1 0.0 6e-56 189.7 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 Keratin_B2_2 PF13885.6 RUS82386.1 - 3.3e-11 43.0 91.6 0.00046 20.1 23.5 3.9 1 1 3 4 4 4 3 Keratin, high sulfur B2 protein PMG PF05287.12 RUS82386.1 - 3e-07 30.7 53.4 2.7e-06 27.5 53.4 1.9 1 1 0 1 1 1 1 PMG protein Sigma70_r4_2 PF08281.12 RUS82386.1 - 5.2 6.8 12.2 6.6 6.5 0.2 5.1 5 2 3 8 8 8 0 Sigma-70, region 4 AAA_lid_1 PF17857.1 RUS82387.1 - 3.2e-20 72.2 0.0 6.2e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 RUS82387.1 - 3.1e-13 49.7 0.0 4.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_6 PF12774.7 RUS82388.1 - 6.6e-35 120.6 0.0 1.2e-34 119.8 0.0 1.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 RUS82388.1 - 2.7e-17 63.0 0.1 6.6e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS82388.1 - 1.5e-08 34.8 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RUS82388.1 - 0.0041 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF853 PF05872.12 RUS82388.1 - 0.034 12.7 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 RUS82388.1 - 0.036 14.5 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RUS82388.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RUS82388.1 - 0.15 12.4 0.2 0.26 11.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RUS82388.1 - 0.25 11.0 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DHC_N2 PF08393.13 RUS82389.1 - 7.8e-119 397.3 11.1 7.8e-119 397.3 11.1 2.5 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 PCI PF01399.27 RUS82389.1 - 0.012 16.1 0.1 0.057 13.9 0.1 2.2 1 0 0 1 1 1 0 PCI domain DHC_N1 PF08385.12 RUS82390.1 - 1.8e-128 429.7 7.3 2.8e-128 429.0 7.3 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF5344 PF17279.2 RUS82390.1 - 0.58 10.8 2.4 3.8 8.1 0.4 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5344) DERM PF14704.6 RUS82391.1 - 2.5e-41 141.6 2.2 3.1e-41 141.4 2.2 1.0 1 0 0 1 1 1 1 Dermatopontin His_Phos_1 PF00300.22 RUS82392.1 - 4.6e-34 117.8 0.0 6.9e-29 100.9 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Caf4 PF11615.8 RUS82393.1 - 0.14 12.2 1.6 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 CCR4-associated factor 4 bcl-2I13 PF12201.8 RUS82394.1 - 0.086 12.7 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Sigma54_AID PF00309.20 RUS82394.1 - 0.13 12.1 3.9 0.19 11.6 3.9 1.2 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) DnaJ PF00226.31 RUS82395.1 - 4.7e-20 71.5 0.2 9.8e-20 70.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain TssO PF17561.2 RUS82395.1 - 0.11 12.6 1.0 4.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO DERM PF14704.6 RUS82396.1 - 3.8e-36 124.8 4.2 4.7e-36 124.6 4.2 1.0 1 0 0 1 1 1 1 Dermatopontin DUF2054 PF10218.9 RUS82396.1 - 0.018 15.2 1.4 0.024 14.7 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) DERM PF14704.6 RUS82398.1 - 2.5e-41 141.6 2.2 3.1e-41 141.4 2.2 1.0 1 0 0 1 1 1 1 Dermatopontin Sulfotransfer_1 PF00685.27 RUS82400.1 - 3.8e-18 65.9 2.0 9.2e-18 64.7 2.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS82400.1 - 3.6e-05 24.2 0.1 4.4e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Rpn3_C PF08375.11 RUS82400.1 - 0.018 15.5 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Abhydrolase_5 PF12695.7 RUS82401.1 - 3.5e-09 36.6 0.0 1.5e-08 34.6 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Motilin_assoc PF04643.12 RUS82401.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Hydrolase_4 PF12146.8 RUS82401.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Myosin_head PF00063.21 RUS82402.1 - 5.5e-169 563.6 0.0 1.3e-120 403.7 0.0 3.5 2 1 2 4 4 4 3 Myosin head (motor domain) AAA_22 PF13401.6 RUS82402.1 - 0.00087 19.6 0.0 0.0067 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 RUS82402.1 - 0.015 15.3 0.1 0.06 13.4 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RUS82402.1 - 0.019 15.3 2.7 0.075 13.4 0.5 3.1 2 1 0 2 2 2 0 AAA ATPase domain Myosin_N PF02736.19 RUS82402.1 - 0.15 11.9 0.1 0.43 10.5 0.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 RUS82402.1 - 0.21 11.5 39.7 1.1 9.2 0.2 5.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif Tubulin PF00091.25 RUS82403.1 - 7.2e-68 228.7 0.0 1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS82403.1 - 6.1e-40 136.3 0.1 1.1e-39 135.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS82403.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain NUC153 PF08159.12 RUS82405.1 - 3.1e-14 52.5 10.2 6.3e-13 48.3 0.7 3.1 3 0 0 3 3 3 2 NUC153 domain CAP_GLY PF01302.25 RUS82406.1 - 6.3e-47 157.4 2.1 2.1e-23 82.1 0.1 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 RUS82406.1 - 1.4e-16 59.9 16.2 6.4e-09 35.5 3.4 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle SOGA PF11365.8 RUS82406.1 - 0.00063 20.8 2.0 0.00063 20.8 2.0 10.8 2 2 10 12 12 12 2 Protein SOGA ERM PF00769.19 RUS82406.1 - 0.002 18.0 13.3 0.002 18.0 13.3 6.3 1 1 5 6 6 5 3 Ezrin/radixin/moesin family APG6_N PF17675.1 RUS82406.1 - 0.0099 16.4 23.2 0.0099 16.4 23.2 9.2 1 1 9 10 10 8 3 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 RUS82406.1 - 0.0099 16.5 8.2 0.0099 16.5 8.2 11.3 1 1 7 10 10 8 2 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC_2 PF13696.6 RUS82406.1 - 0.17 11.8 0.9 0.36 10.7 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 RUS82406.1 - 0.29 10.9 3.3 0.77 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle ATG16 PF08614.11 RUS82406.1 - 0.79 9.9 191.5 0.014 15.6 16.9 9.4 1 1 7 8 8 6 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 RUS82406.1 - 1.1 7.0 178.5 0.012 13.5 105.9 3.7 1 1 2 3 3 3 0 Myosin tail zf-U1 PF06220.12 RUS82406.1 - 4 7.3 4.0 4.6 7.1 1.0 2.3 2 0 0 2 2 2 0 U1 zinc finger LSM PF01423.22 RUS82407.1 - 2.8e-15 55.8 0.1 3.5e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.18 RUS82407.1 - 0.066 13.5 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Kringle domain DUF3128 PF11326.8 RUS82409.1 - 1.1e-11 44.9 5.1 1.5e-11 44.5 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Phage_T4_Ndd PF06591.11 RUS82409.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) UPF0203 PF05254.12 RUS82409.1 - 0.11 12.7 3.5 0.18 12.1 3.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cas_Csy2 PF09614.10 RUS82409.1 - 0.15 11.4 0.1 0.15 11.4 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Spb1_C PF07780.12 RUS82410.1 - 1.3e-64 217.7 25.1 1.3e-64 217.7 25.1 4.1 2 1 1 3 3 3 2 Spb1 C-terminal domain LRAT PF04970.13 RUS82410.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.3 3 1 1 4 4 4 0 Lecithin retinol acyltransferase FtsJ PF01728.19 RUS82411.1 - 1.9e-53 181.2 0.0 2.5e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 RUS82411.1 - 1.4e-32 112.8 1.0 2.3e-32 112.1 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 RUS82411.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain eIF-3c_N PF05470.12 RUS82412.1 - 2.1e-221 736.4 18.5 4.5e-221 735.3 18.5 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 RUS82412.1 - 2.2e-14 53.8 0.1 1e-13 51.7 0.1 2.3 1 0 0 1 1 1 1 PCI domain SLATT_fungal PF18142.1 RUS82412.1 - 0.27 11.2 1.8 0.6 10.1 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF2956 PF11169.8 RUS82412.1 - 7.3 6.8 9.1 4.5 7.5 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) 14-3-3 PF00244.20 RUS82413.1 - 5.6e-105 349.8 3.6 6.4e-105 349.6 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_S64 PF08192.11 RUS82413.1 - 0.049 12.1 0.1 0.061 11.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 VWA PF00092.28 RUS82415.1 - 1.2e-29 103.8 0.0 2.1e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS82415.1 - 4.7e-09 36.8 0.0 1.6e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS82415.1 - 0.0051 16.8 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 von Willebrand factor type A domain HYR PF02494.16 RUS82416.1 - 2.1e-24 85.6 7.5 7.3e-15 55.1 0.2 2.6 2 0 0 2 2 2 2 HYR domain Sushi PF00084.20 RUS82416.1 - 2.6e-22 79.1 36.9 9.4e-08 32.5 2.6 5.5 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) Ephrin_rec_like PF07699.13 RUS82416.1 - 2.4e-06 27.2 1.9 2.4e-05 24.0 1.9 3.0 1 0 0 1 1 1 1 Putative ephrin-receptor like cEGF PF12662.7 RUS82416.1 - 0.62 10.1 30.0 2.5 8.1 0.3 6.4 5 1 0 5 5 5 0 Complement Clr-like EGF-like Kazal_1 PF00050.21 RUS82416.1 - 5.5 7.1 15.8 0.14 12.2 2.8 3.5 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain HRM PF02793.22 RUS82416.1 - 7 7.0 20.4 2.4 8.5 1.0 4.8 2 1 0 3 3 3 0 Hormone receptor domain Sushi PF00084.20 RUS82417.1 - 0 1359.0 344.5 2.9e-12 47.0 1.8 52.4 52 0 0 52 52 52 51 Sushi repeat (SCR repeat) EGF PF00008.27 RUS82417.1 - 5.5e-37 125.7 137.5 1.2e-06 28.6 7.2 13.4 9 0 0 9 9 9 9 EGF-like domain Ephrin_rec_like PF07699.13 RUS82417.1 - 1.1e-33 114.7 55.2 2.7e-13 49.5 5.9 7.9 6 1 1 7 7 7 3 Putative ephrin-receptor like Pentaxin PF00354.17 RUS82417.1 - 9.3e-23 80.9 0.0 1.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family hEGF PF12661.7 RUS82417.1 - 9.2e-22 76.9 130.0 1.3e-05 25.6 4.5 15.4 13 0 0 13 13 13 9 Human growth factor-like EGF EGF_2 PF07974.13 RUS82417.1 - 1.8e-13 50.6 163.1 0.0044 17.4 11.4 13.0 9 0 0 9 9 9 9 EGF-like domain Laminin_G_3 PF13385.6 RUS82417.1 - 6e-12 46.0 1.4 1.3e-11 44.9 1.4 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 RUS82417.1 - 9.7e-07 28.9 46.1 1.5e-05 25.1 8.8 19.4 18 4 4 22 22 22 4 Calcium-binding EGF domain Dicty_CTDC PF00526.18 RUS82417.1 - 0.15 12.0 10.4 6.1 6.8 10.4 4.2 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat DUF5423 PF17461.2 RUS82418.1 - 1.5 7.6 7.4 0.1 11.4 2.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Y_phosphatase PF00102.27 RUS82419.1 - 6.7e-86 287.7 0.8 1.5e-42 145.7 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 RUS82419.1 - 0.00011 22.0 0.2 0.0044 16.8 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Amidase PF01425.21 RUS82420.1 - 5.3e-96 322.3 0.0 6.8e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3808 PF10300.9 RUS82422.1 - 2.9e-144 481.4 4.4 2.9e-144 481.4 4.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 RUS82422.1 - 1.3e-07 31.8 0.2 2.7e-05 24.4 0.7 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS82422.1 - 0.0021 18.0 9.1 3.9 7.8 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS82422.1 - 0.012 15.0 0.1 0.11 11.8 0.2 2.3 3 0 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 RUS82422.1 - 0.017 15.7 0.4 7.5 7.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS82422.1 - 0.071 13.6 0.0 32 5.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Plasmid_RAQPRD PF09686.10 RUS82422.1 - 0.18 12.0 0.9 3.1 8.1 0.4 2.7 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Lipase PF00151.19 RUS82423.1 - 4e-82 276.2 0.0 4.8e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS82423.1 - 0.0014 19.2 0.8 0.0026 18.4 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 RUS82423.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase EGF_CA PF07645.15 RUS82424.1 - 1.3e-65 217.4 379.7 1.6e-10 41.0 6.8 23.2 20 3 3 23 23 23 15 Calcium-binding EGF domain cEGF PF12662.7 RUS82424.1 - 1.6e-39 133.4 245.5 1.9e-06 27.6 3.5 23.6 24 1 0 24 24 24 17 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS82424.1 - 8.3e-39 131.6 349.0 6.5e-07 29.5 9.4 22.8 17 4 6 23 23 23 16 Coagulation Factor Xa inhibitory site NIDO PF06119.14 RUS82424.1 - 5.9e-10 40.0 1.1 2.6e-09 37.9 1.1 2.3 1 0 0 1 1 1 1 Nidogen-like SEA PF01390.20 RUS82424.1 - 2.4e-06 27.6 2.5 0.024 14.7 0.2 3.0 3 0 0 3 3 3 2 SEA domain EGF_2 PF07974.13 RUS82424.1 - 0.0032 17.8 15.4 0.0032 17.8 15.4 24.8 19 6 3 22 22 22 2 EGF-like domain Plasmod_Pvs28 PF06247.11 RUS82424.1 - 0.0044 17.3 4.9 0.0044 17.3 4.9 19.8 19 2 0 19 19 19 4 Pvs28 EGF domain Cadherin_5 PF17892.1 RUS82424.1 - 0.013 15.4 0.3 0.013 15.4 0.3 4.6 4 0 0 4 4 4 0 Cadherin-like domain SKG6 PF08693.10 RUS82424.1 - 0.6 9.6 2.0 0.49 9.8 0.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ApeC PF16977.5 RUS82425.1 - 1.3e-54 185.2 2.4 2.2e-54 184.5 2.4 1.4 1 0 0 1 1 1 1 C-terminal domain of apextrin DUF1690 PF07956.11 RUS82425.1 - 0.012 16.1 2.4 0.02 15.3 2.4 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) CsoSCA PF08936.10 RUS82425.1 - 0.16 10.6 1.4 0.26 9.9 1.4 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Prominin PF05478.11 RUS82425.1 - 0.59 8.0 5.7 0.83 7.5 5.7 1.1 1 0 0 1 1 1 0 Prominin Ig_3 PF13927.6 RUS82426.1 - 0.024 15.2 1.3 0.22 12.2 1.3 2.1 1 1 0 1 1 1 0 Immunoglobulin domain ApeC PF16977.5 RUS82427.1 - 2.6e-56 190.8 2.4 3.7e-56 190.3 2.4 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin Exonuc_VII_L PF02601.15 RUS82427.1 - 0.0002 21.0 0.2 0.00026 20.7 0.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Apolipoprotein PF01442.18 RUS82427.1 - 0.0098 15.8 8.0 0.017 15.0 8.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.11 RUS82427.1 - 0.054 14.1 8.4 0.12 12.9 8.4 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 RUS82427.1 - 0.062 13.3 6.6 0.064 13.3 5.3 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CTNNB1_binding PF08347.11 RUS82427.1 - 0.2 11.8 3.4 0.39 10.9 3.5 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding DUF1664 PF07889.12 RUS82427.1 - 0.23 11.5 4.9 0.26 11.3 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MtrG PF04210.13 RUS82427.1 - 0.24 11.3 1.0 0.72 9.7 0.2 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ZYG-11_interact PF05884.12 RUS82427.1 - 0.31 10.4 1.3 0.45 9.9 1.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 FTCD_C PF04961.12 RUS82427.1 - 0.75 9.5 2.1 0.89 9.3 0.8 1.6 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase TMPIT PF07851.13 RUS82427.1 - 1.6 7.9 6.0 0.7 9.1 3.7 1.5 2 0 0 2 2 2 0 TMPIT-like protein DUF2852 PF11014.8 RUS82427.1 - 2.7 8.2 4.2 2.4 8.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) FapA PF03961.13 RUS82427.1 - 4.9 5.6 5.4 6.6 5.2 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF883 PF05957.13 RUS82427.1 - 5 7.8 8.1 15 6.3 0.7 3.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) NPV_P10 PF05531.12 RUS82427.1 - 5.6 7.5 7.3 4.9e+02 1.3 7.1 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4572 PF15139.6 RUS82428.1 - 3.5e-57 193.5 8.0 4.5e-57 193.1 8.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) Laminin_EGF PF00053.24 RUS82429.1 - 2e-158 514.5 445.4 1.1e-10 41.5 11.6 23.7 21 3 2 23 23 23 22 Laminin EGF domain Laminin_G_2 PF02210.24 RUS82429.1 - 1.1e-119 394.4 3.8 5.7e-28 98.0 0.0 6.3 6 0 0 6 6 6 5 Laminin G domain Laminin_G_1 PF00054.23 RUS82429.1 - 4.6e-112 369.8 4.6 5.4e-27 94.6 0.1 5.9 6 0 0 6 6 6 5 Laminin G domain Laminin_N PF00055.17 RUS82429.1 - 4.3e-73 245.8 0.0 4.3e-73 245.8 0.0 3.6 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 RUS82429.1 - 4e-36 123.9 0.0 8.3e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 RUS82429.1 - 1.7e-23 83.5 1.3 0.00024 21.3 0.0 6.1 6 0 0 6 6 6 5 Concanavalin A-like lectin/glucanases superfamily Laminin_II PF06009.12 RUS82429.1 - 2e-12 47.3 2.0 2e-12 47.3 2.0 4.8 2 1 3 6 6 6 1 Laminin Domain II DUF1080 PF06439.11 RUS82429.1 - 0.00015 21.9 0.1 2.5 8.2 0.0 3.5 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1080) DUF16 PF01519.16 RUS82429.1 - 0.0022 18.4 2.3 0.006 17.1 0.6 2.6 2 0 0 2 2 2 1 Protein of unknown function DUF16 DUF948 PF06103.11 RUS82429.1 - 0.39 11.0 18.3 6.6 7.1 0.6 5.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) TPR_2 PF07719.17 RUS82430.1 - 8e-10 38.1 0.0 0.01 15.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS82430.1 - 1.4e-06 28.3 0.0 0.16 12.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS82430.1 - 8.2e-06 25.4 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS82430.1 - 5.2e-05 23.7 0.1 0.03 15.1 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS82430.1 - 0.00012 21.7 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 RUS82430.1 - 0.0058 17.3 0.0 4 8.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2271 PF10029.9 RUS82430.1 - 0.0082 15.8 0.5 1.5 8.5 0.1 2.4 2 0 0 2 2 2 2 Predicted periplasmic protein (DUF2271) TPR_9 PF13371.6 RUS82430.1 - 0.0094 16.1 0.0 0.82 9.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS82430.1 - 0.056 14.0 0.0 4.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS82430.1 - 0.13 12.3 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5580 PF17743.1 RUS82431.1 - 4.2e-22 78.4 0.1 6.7e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_7 PF13499.6 RUS82431.1 - 0.45 11.0 4.8 5 7.6 0.4 3.1 3 0 0 3 3 3 0 EF-hand domain pair MFS_1 PF07690.16 RUS82432.1 - 0.00016 20.7 12.8 0.00016 20.7 12.8 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily YqhR PF11085.8 RUS82432.1 - 1.9 8.4 8.5 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Conserved membrane protein YqhR MFS_1 PF07690.16 RUS82435.1 - 4e-05 22.7 11.2 4.5e-05 22.5 11.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SID-1_RNA_chan PF13965.6 RUS82435.1 - 0.26 9.7 7.4 0.32 9.4 7.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SPC25 PF06703.11 RUS82435.1 - 0.38 10.5 3.5 0.5 10.1 3.5 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UNC-93 PF05978.16 RUS82435.1 - 0.49 10.1 10.3 0.63 9.7 10.3 1.1 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Miga PF10265.9 RUS82436.1 - 1.1e-11 44.4 8.7 2.3e-11 43.4 8.7 1.5 1 1 0 1 1 1 1 Mitoguardin LapA_dom PF06305.11 RUS82436.1 - 0.18 11.6 3.0 0.35 10.7 3.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SUIM_assoc PF16619.5 RUS82436.1 - 0.4 10.8 5.1 1.2 9.2 5.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Gln-synt_C PF00120.24 RUS82437.1 - 1.2e-17 63.9 0.0 3.8e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 RUS82437.1 - 1.3e-14 53.7 0.0 2.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DAAD PF18752.1 RUS82438.1 - 0.15 11.8 8.0 0.22 11.3 8.0 1.2 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase SAP130_C PF16014.5 RUS82438.1 - 0.78 8.8 12.9 0.87 8.6 12.9 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus ShK PF01549.24 RUS82438.1 - 9.6 6.8 13.5 0.92 10.1 8.6 1.9 2 0 0 2 2 2 0 ShK domain-like SAP130_C PF16014.5 RUS82439.1 - 0.041 13.0 3.6 0.045 12.9 3.6 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Man-6-P_recep PF02157.15 RUS82440.1 - 1.1e-14 54.1 0.1 1.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 RUS82440.1 - 3.2e-13 50.1 0.7 7.4e-13 49.0 0.7 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 Furin-like PF00757.20 RUS82441.1 - 5.4 6.9 24.6 10 5.9 24.6 1.5 1 0 0 1 1 1 0 Furin-like cysteine rich region IgGFc_binding PF17517.2 RUS82442.1 - 1.6e-09 37.5 0.1 1.7e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 IgGFc binding protein Ras PF00071.22 RUS82444.1 - 4.3e-31 107.7 1.6 4.7e-30 104.3 1.6 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS82444.1 - 3.2e-14 53.2 0.2 3.7e-13 49.7 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 RUS82444.1 - 2.3e-05 24.2 0.3 0.0054 16.5 0.0 2.1 1 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RUS82444.1 - 0.0014 18.1 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Arf PF00025.21 RUS82444.1 - 0.0044 16.5 0.5 0.37 10.2 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 RUS82444.1 - 0.012 15.1 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 RUS82444.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 RUS82444.1 - 0.02 14.1 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 RUS82444.1 - 0.03 14.4 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS82444.1 - 0.067 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Tfb5 PF06331.12 RUS82444.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 RsgA_GTPase PF03193.16 RUS82444.1 - 0.19 11.7 0.6 16 5.3 0.0 2.8 1 1 2 3 3 3 0 RsgA GTPase MFS_1 PF07690.16 RUS82445.1 - 4.9e-13 48.7 7.0 6.6e-13 48.3 7.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS82445.1 - 8.5e-09 34.8 14.1 9.8e-09 34.6 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HlyIII PF03006.20 RUS82445.1 - 0.069 12.9 6.9 0.12 12.1 6.9 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF1345 PF07077.11 RUS82445.1 - 0.082 12.6 4.3 0.18 11.5 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF4231 PF14015.6 RUS82445.1 - 0.23 12.0 5.3 0.99 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) CCB1 PF12046.8 RUS82445.1 - 0.38 10.1 5.3 3.9 6.8 2.0 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B DUF3043 PF11241.8 RUS82445.1 - 2.9 7.9 4.3 0.93 9.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) Trep_Strep PF09605.10 RUS82445.1 - 6.5 6.7 16.6 0.32 11.0 8.2 2.1 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Sugar_tr PF00083.24 RUS82446.1 - 1.4e-11 44.0 2.9 1.7e-11 43.6 2.9 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS82446.1 - 1.7e-06 27.2 11.6 1.7e-06 27.2 11.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 RUS82446.1 - 0.00031 20.2 4.7 0.00031 20.2 4.7 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Abhydro_lipase PF04083.16 RUS82447.1 - 3e-23 81.1 0.0 8.8e-22 76.5 0.0 2.4 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RUS82447.1 - 2.2e-20 73.4 0.1 3.4e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS82447.1 - 3e-06 26.7 0.3 0.00051 19.4 0.1 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS82447.1 - 0.0036 17.9 0.0 0.0046 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ig_3 PF13927.6 RUS82448.1 - 2.4e-20 72.9 0.7 1.5e-11 44.8 0.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS82448.1 - 4.4e-15 55.5 0.0 7.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS82448.1 - 2.4e-09 37.2 0.1 1.4e-06 28.3 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS82448.1 - 3.5e-09 36.9 0.1 1.7e-05 25.1 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS82448.1 - 2.4e-05 24.3 0.3 0.039 14.0 0.3 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS82448.1 - 6.8e-05 23.0 0.7 0.86 9.8 0.0 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.15 RUS82448.1 - 0.012 16.0 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin C1-set domain dsrm PF00035.26 RUS82449.1 - 3.5e-24 85.3 0.2 4e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif HA2 PF04408.23 RUS82449.1 - 2.5e-15 56.7 0.0 5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RUS82449.1 - 6.4e-15 55.5 0.0 1.7e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 RUS82449.1 - 7.3e-15 55.1 0.1 1.6e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 RUS82449.1 - 9.2e-09 35.3 0.1 2e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 RUS82449.1 - 0.0003 20.2 0.0 0.00072 19.0 0.0 1.6 1 0 0 1 1 1 1 KaiC DND1_DSRM PF14709.7 RUS82449.1 - 0.018 15.3 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 RUS82449.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RUS82449.1 - 0.076 12.5 0.2 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 RUS82449.1 - 0.077 13.3 1.8 0.93 9.8 1.4 2.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 RUS82449.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 RUS82449.1 - 0.1 12.7 0.5 3.1 7.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 RUS82449.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 RUS82449.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region 4PPT_N PF17837.1 RUS82450.1 - 0.0016 18.6 6.2 2 8.6 0.1 3.5 4 0 0 4 4 4 2 4'-phosphopantetheinyl transferase N-terminal domain LIP1 PF15904.5 RUS82450.1 - 0.0086 16.4 0.0 14 6.1 0.0 3.0 1 1 2 3 3 3 3 LKB1 serine/threonine kinase interacting protein 1 DUF2584 PF10763.9 RUS82450.1 - 0.0095 16.1 0.5 44 4.3 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2584) DUF2379 PF09543.10 RUS82450.1 - 0.18 12.0 0.1 1.3e+02 2.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Alanine_zipper PF11839.8 RUS82451.1 - 0.00036 20.8 15.3 0.00036 20.8 15.3 3.4 3 0 0 3 3 2 1 Alanine-zipper, major outer membrane lipoprotein DUF4349 PF14257.6 RUS82451.1 - 0.0027 17.2 3.8 0.0057 16.1 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) RraB PF06877.11 RUS82451.1 - 0.14 12.9 6.3 0.069 13.9 3.6 1.9 2 0 0 2 2 2 0 Regulator of ribonuclease activity B YlqD PF11068.8 RUS82451.1 - 0.17 12.3 5.5 0.53 10.7 5.5 1.8 1 0 0 1 1 1 0 YlqD protein DUF2570 PF10828.8 RUS82451.1 - 0.27 11.1 3.8 0.66 9.8 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MCU PF04678.13 RUS82451.1 - 0.41 10.7 3.4 1.1 9.3 3.4 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spectrin PF00435.21 RUS82451.1 - 0.65 10.5 12.4 0.7 10.4 0.5 2.9 2 1 1 3 3 3 0 Spectrin repeat AAA_13 PF13166.6 RUS82451.1 - 0.74 8.4 8.4 1.5 7.4 8.4 1.4 1 0 0 1 1 1 0 AAA domain DUF1702 PF08012.11 RUS82451.1 - 0.85 8.4 4.3 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1702) Atg14 PF10186.9 RUS82451.1 - 6.6 5.7 10.3 16 4.5 10.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MSP1_C PF07462.11 RUS82451.1 - 7.4 5.1 12.6 2 7.0 2.5 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus G-alpha PF00503.20 RUS82452.1 - 1.5e-122 409.2 5.8 1.7e-122 409.0 5.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS82452.1 - 3.8e-17 62.3 2.5 4.3e-13 49.1 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS82452.1 - 3.1e-06 26.7 6.8 0.00034 20.1 3.3 2.9 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RUS82452.1 - 0.00057 20.1 3.8 0.21 11.8 0.1 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RUS82452.1 - 0.0075 15.7 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Ras PF00071.22 RUS82452.1 - 0.01 15.5 3.6 0.22 11.1 1.1 2.4 2 0 0 2 2 2 0 Ras family PROCN PF08083.11 RUS82452.1 - 0.066 11.9 0.1 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 PROCN (NUC071) domain AAA_29 PF13555.6 RUS82452.1 - 0.079 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS82452.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Tmemb_18A PF09771.9 RUS82453.1 - 5.2e-54 181.7 0.2 5.9e-54 181.5 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 UPF0182 PF03699.13 RUS82453.1 - 0.28 9.3 0.5 0.31 9.1 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4131 PF13567.6 RUS82453.1 - 2.9 7.5 6.2 0.73 9.5 0.6 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DSPc PF00782.20 RUS82454.1 - 1.3e-32 112.4 0.0 1.9e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS82454.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Fibrinogen_C PF00147.18 RUS82455.1 - 4.2e-16 59.4 1.6 2.7e-15 56.8 0.0 2.0 1 1 1 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.13 RUS82455.1 - 0.057 13.8 3.5 0.12 12.7 3.5 1.6 1 0 0 1 1 1 0 EGF-like domain Peptidase_M7 PF02031.16 RUS82455.1 - 0.2 11.8 2.4 0.98 9.5 0.3 2.6 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Fibrinogen_C PF00147.18 RUS82456.1 - 3.6e-16 59.6 0.4 4.9e-16 59.2 0.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MFS_1 PF07690.16 RUS82457.1 - 9.9e-24 83.9 13.5 1.2e-23 83.6 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS82457.1 - 5.2e-21 75.0 2.4 5.6e-21 74.9 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RUS82457.1 - 6.2e-09 35.6 2.2 8.5e-09 35.2 2.2 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 RUS82457.1 - 1.6e-05 23.6 6.0 3.3e-05 22.6 5.2 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 RUS82457.1 - 0.005 15.2 2.3 0.005 15.2 0.6 1.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 RUS82457.1 - 0.044 12.6 3.9 0.086 11.7 3.9 1.5 1 1 0 1 1 1 0 MFS_1 like family FAR1 PF03101.15 RUS82458.1 - 5.4e-05 23.8 1.7 6.5e-05 23.6 0.2 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF5575 PF17738.1 RUS82458.1 - 0.00078 18.6 0.3 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5575) BESS PF02944.20 RUS82458.1 - 0.00096 18.9 0.1 0.046 13.6 0.0 2.6 2 0 0 2 2 2 1 BESS motif GDYXXLXY PF14345.6 RUS82458.1 - 0.11 12.3 0.1 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 GDYXXLXY protein DUF1983 PF09327.11 RUS82460.1 - 0.068 13.3 0.1 93 3.2 0.0 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1983) DUF4538 PF15061.6 RUS82461.1 - 6.5e-20 70.6 0.1 7.4e-20 70.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) PP2C PF00481.21 RUS82462.1 - 1.9e-70 237.4 0.3 2.8e-70 236.9 0.3 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS82462.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3915 PF13054.6 RUS82462.1 - 0.0011 18.9 0.4 0.0024 17.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS82462.1 - 0.003 16.0 6.4 0.004 15.5 6.4 1.1 1 0 0 1 1 1 1 Atrophin-1 family SH3_9 PF14604.6 RUS82463.1 - 6.2e-51 170.0 2.2 7e-14 51.4 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 RUS82463.1 - 1e-50 169.1 0.9 3.6e-12 45.7 0.0 4.4 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 RUS82463.1 - 2e-36 123.5 1.1 3.5e-11 42.6 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4_2 PF13923.6 RUS82463.1 - 6.2e-08 32.4 13.2 1.2e-07 31.4 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82463.1 - 1.6e-07 31.1 12.9 3.2e-07 30.1 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS82463.1 - 2.9e-07 30.7 15.3 3.1e-07 30.6 13.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS82463.1 - 3.8e-06 26.8 10.2 9.5e-06 25.5 10.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS82463.1 - 9.8e-06 25.4 11.9 1.9e-05 24.5 11.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS82463.1 - 5e-05 23.1 11.0 9.4e-05 22.2 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS82463.1 - 0.00014 21.9 10.8 0.00027 21.0 10.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RUS82463.1 - 0.0017 18.1 10.8 0.0045 16.8 10.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 RUS82463.1 - 0.0075 16.1 8.4 0.17 11.7 8.7 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RUS82463.1 - 0.44 10.9 8.7 1 9.7 8.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 RUS82463.1 - 0.63 9.9 7.3 1.3 8.9 7.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 RUS82463.1 - 2.4 8.8 9.7 0.92 10.1 1.6 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-RING_11 PF17123.5 RUS82463.1 - 5.1 6.9 11.1 2 8.3 6.3 2.5 1 1 1 2 2 2 0 RING-like zinc finger Pou PF00157.17 RUS82464.1 - 1.6e-30 104.9 0.0 3.3e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 RUS82464.1 - 1.5e-17 63.2 1.6 2.8e-17 62.3 1.6 1.5 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 RUS82464.1 - 0.00036 20.8 0.3 0.071 13.5 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain DUF4770 PF15994.5 RUS82464.1 - 0.037 14.3 0.8 0.06 13.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Homeobox_KN PF05920.11 RUS82464.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain U6-snRNA_bdg PF10596.9 RUS82465.1 - 0.0035 17.3 1.0 0.11 12.4 0.1 2.3 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 GLTT PF01744.20 RUS82465.1 - 0.031 14.0 4.0 1.1 9.1 0.1 3.1 3 0 0 3 3 3 0 GLTT repeat (6 copies) BRX PF08381.11 RUS82465.1 - 0.32 10.4 2.1 9.4 5.7 0.3 2.4 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Ole-e-6 PF09253.10 RUS82466.1 - 0.075 13.0 4.3 17 5.5 0.1 3.6 3 0 0 3 3 3 0 Pollen allergen ole e 6 HLH PF00010.26 RUS82467.1 - 2.3e-17 62.7 0.4 3.3e-17 62.2 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 RUS82467.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF512 PF04459.12 RUS82467.1 - 0.25 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) ACPS PF01648.20 RUS82468.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily CD36 PF01130.21 RUS82469.1 - 1.1e-103 347.3 0.0 1.3e-103 347.1 0.0 1.0 1 0 0 1 1 1 1 CD36 family PorA PF11271.8 RUS82469.1 - 0.018 14.3 0.0 2.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Porin PorA CD36 PF01130.21 RUS82470.1 - 1.8e-140 468.6 0.0 2.2e-140 468.3 0.0 1.0 1 0 0 1 1 1 1 CD36 family L_protein_N PF15518.6 RUS82470.1 - 0.054 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 L protein N-terminus Gelsolin PF00626.22 RUS82470.1 - 0.15 11.9 0.4 0.34 10.8 0.4 1.5 1 0 0 1 1 1 0 Gelsolin repeat 2OG-FeII_Oxy_2 PF13532.6 RUS82471.1 - 2.3e-20 73.6 0.0 5.1e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 RUS82471.1 - 8.5e-16 58.4 0.2 2.1e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS82471.1 - 1e-13 51.8 0.1 3.5e-13 50.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 RUS82471.1 - 5.4e-08 32.5 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.6 RUS82471.1 - 1.4e-06 28.2 0.0 3.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS82471.1 - 4.2e-06 27.4 0.3 2.4e-05 25.0 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RUS82471.1 - 6.6e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 RUS82471.1 - 0.00082 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS82471.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 RUS82471.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 RUS82471.1 - 0.037 12.6 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1818 PF08848.11 RUS82471.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) Neur_chan_memb PF02932.16 RUS82472.1 - 1.4e-11 44.9 0.2 1.4e-11 44.9 0.2 2.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region HemY_N PF07219.13 RUS82472.1 - 0.052 13.7 0.0 0.052 13.7 0.0 2.0 2 1 1 3 3 3 0 HemY protein N-terminus DUF485 PF04341.12 RUS82472.1 - 8 6.5 8.7 0.14 12.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Foie-gras_1 PF11817.8 RUS82473.1 - 1.2e-66 225.0 1.2 1.2e-66 225.0 1.2 1.6 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 RUS82473.1 - 3.7e-13 49.1 2.0 1.8e-09 36.9 0.3 2.7 3 0 0 3 3 3 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 RUS82473.1 - 4.9e-12 45.6 0.1 1.1e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF2606 PF10794.9 RUS82473.1 - 0.009 15.8 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2606) TRAPPC10 PF12584.8 RUS82473.1 - 0.067 12.9 0.0 0.29 10.8 0.0 1.9 1 1 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 SCAPER_N PF16501.5 RUS82473.1 - 0.12 12.4 0.1 0.42 10.6 0.1 2.0 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum SBF_like PF13593.6 RUS82474.1 - 8.9e-76 255.2 24.7 1.1e-75 254.9 24.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 RUS82474.1 - 3e-12 46.6 13.4 3e-12 46.6 13.4 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family HORMA PF02301.18 RUS82475.1 - 4.3e-07 29.7 0.0 9.2e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 HORMA domain Ima1_N PF09779.9 RUS82476.1 - 2.2e-08 35.1 1.2 2.2e-08 35.1 1.2 2.3 2 0 0 2 2 2 1 Ima1 N-terminal domain TBCA PF02970.16 RUS82476.1 - 0.16 12.3 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A 2-Hacid_dh_C PF02826.19 RUS82477.1 - 4.3e-60 202.1 0.0 8.2e-60 201.2 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS82477.1 - 3.6e-23 81.7 0.0 4.3e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 RUS82477.1 - 6.1e-05 23.2 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 RUS82477.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RUS82477.1 - 0.0059 17.2 0.1 0.051 14.2 0.1 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2 PF00096.26 RUS82479.1 - 4.5e-13 48.9 40.5 0.0036 17.7 0.1 8.1 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS82479.1 - 2.9e-11 43.2 39.8 0.025 15.4 0.2 8.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS82479.1 - 1.9e-05 24.9 6.0 7.2e-05 23.0 1.6 8.0 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS82479.1 - 0.041 13.9 0.3 0.041 13.9 0.3 5.8 7 0 0 7 7 7 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 RUS82479.1 - 1.9 8.1 6.3 24 4.6 0.2 3.7 4 0 0 4 4 4 0 TFIIB zinc-binding zf-met PF12874.7 RUS82479.1 - 5.2 7.6 14.1 12 6.5 0.0 6.0 8 0 0 8 8 8 0 Zinc-finger of C2H2 type PHD PF00628.29 RUS82485.1 - 2.3e-06 27.4 3.4 4.4e-06 26.5 3.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS82485.1 - 3.8e-06 26.3 3.7 7.1e-06 25.5 3.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 RUS82485.1 - 0.18 11.7 2.8 0.34 10.9 2.8 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 RUS82485.1 - 4.4 7.3 9.2 0.35 10.8 2.5 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UVR PF02151.19 RUS82487.1 - 0.00063 19.4 20.5 0.019 14.7 6.2 3.1 3 0 0 3 3 3 2 UvrB/uvrC motif XRCC1_N PF01834.16 RUS82487.1 - 0.005 16.9 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 XRCC1 N terminal domain OAD_gamma PF04277.13 RUS82487.1 - 0.0091 16.6 0.8 0.13 12.9 0.0 3.2 3 0 0 3 3 3 1 Oxaloacetate decarboxylase, gamma chain AAA_23 PF13476.6 RUS82487.1 - 2 8.9 8.6 0.94 9.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain Cadherin PF00028.17 RUS82488.1 - 6.2e-10 39.4 4.9 8.2e-08 32.6 0.3 3.2 4 0 0 4 4 4 2 Cadherin domain Cadherin_5 PF17892.1 RUS82488.1 - 0.0073 16.3 2.4 0.0073 16.3 2.4 2.7 3 0 0 3 3 3 1 Cadherin-like domain Y_Y_Y PF07495.13 RUS82488.1 - 0.0086 16.0 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Y_Y_Y domain Cadherin_4 PF17803.1 RUS82488.1 - 0.016 15.8 1.8 0.016 15.8 1.8 3.6 2 1 0 2 2 2 0 Bacterial cadherin-like domain DUF4625 PF15418.6 RUS82488.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) CDC45 PF02724.14 RUS82490.1 - 2.6e-05 22.7 23.0 3.3e-05 22.4 23.0 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS82490.1 - 5.7e-05 22.7 34.5 7.1e-05 22.4 34.5 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS82490.1 - 0.045 12.0 44.4 0.058 11.6 44.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS82490.1 - 0.17 11.2 38.3 0.21 10.9 38.3 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 RUS82490.1 - 0.25 9.7 33.3 0.31 9.4 33.3 1.2 1 0 0 1 1 1 0 Mpp10 protein Trypan_PARP PF05887.11 RUS82491.1 - 0.0099 15.9 69.2 0.077 13.0 28.3 3.5 2 1 2 4 4 4 3 Procyclic acidic repetitive protein (PARP) 7TM_GPCR_Srw PF10324.9 RUS82492.1 - 5.8e-39 134.2 19.7 1.2e-38 133.3 19.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS82492.1 - 4.3e-18 65.6 11.4 6.5e-18 65.0 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 RUS82492.1 - 9.2e-05 21.7 18.8 0.00022 20.5 18.9 1.5 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) CDP-OH_P_transf PF01066.21 RUS82492.1 - 0.051 14.4 5.3 11 6.8 5.3 3.4 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase UPF0542 PF15086.6 RUS82492.1 - 0.081 12.9 1.4 0.27 11.2 1.4 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DinB_2 PF12867.7 RUS82493.1 - 0.42 11.1 2.3 56 4.3 0.3 3.8 1 1 1 2 2 2 0 DinB superfamily Ribosomal_L29 PF00831.23 RUS82493.1 - 4.3 7.4 15.8 24 5.0 0.7 4.4 1 1 4 5 5 5 0 Ribosomal L29 protein Connexin43 PF03508.13 RUS82493.1 - 6.2 6.5 16.9 70 3.1 0.2 5.2 5 0 0 5 5 5 0 Gap junction alpha-1 protein (Cx43) PT PF04886.12 RUS82493.1 - 6.9 6.3 34.7 12 5.5 0.9 4.9 4 1 0 4 4 4 0 PT repeat DUF2798 PF11391.8 RUS82494.1 - 3.3e-05 23.8 79.9 5.2 7.2 12.7 7.7 1 1 3 4 4 4 2 Protein of unknown function (DUF2798) Gly-zipper_Omp PF13488.6 RUS82494.1 - 4.1e-05 23.5 38.4 0.035 14.1 5.6 5.3 1 1 2 3 3 3 2 Glycine zipper Gly-zipper_YMGG PF13441.6 RUS82494.1 - 0.042 13.6 16.4 2.5 7.9 0.6 4.3 2 2 1 3 3 3 0 YMGG-like Gly-zipper Romo1 PF10247.9 RUS82494.1 - 0.11 12.9 42.9 7.3 7.0 1.4 7.3 2 2 3 5 5 5 0 Reactive mitochondrial oxygen species modulator 1 DUF5455 PF17537.2 RUS82494.1 - 4.3 7.8 45.2 19 5.7 4.0 7.6 1 1 2 3 3 3 0 Family of unknown function (DUF5455) PT PF04886.12 RUS82495.1 - 1.9e-51 171.3 173.9 1.8e+04 -88.7 173.9 7.2 1 1 0 1 1 1 0 PT repeat Glycos_transf_2 PF00535.26 RUS82496.1 - 9.3e-24 84.1 0.0 1.3e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS82496.1 - 4.8e-09 36.5 0.1 1.2e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 RUS82496.1 - 3.3e-07 30.0 0.0 5.9e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 RUS82496.1 - 2e-06 27.9 0.0 5.2e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS82496.1 - 2.3e-06 27.2 0.0 5.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase WSC PF01822.19 RUS82497.1 - 9.2e-08 32.2 3.4 1.7e-07 31.3 3.4 1.5 1 0 0 1 1 1 1 WSC domain Nop14 PF04147.12 RUS82498.1 - 0.0055 15.0 71.7 0.044 12.0 39.5 2.1 2 0 0 2 2 2 2 Nop14-like family SDA1 PF05285.12 RUS82498.1 - 0.15 11.5 72.9 0.11 11.9 21.6 2.1 2 0 0 2 2 2 0 SDA1 Mpp10 PF04006.12 RUS82498.1 - 4.1 5.7 64.6 0.79 8.1 21.5 2.1 2 0 0 2 2 2 0 Mpp10 protein PARM PF17061.5 RUS82499.1 - 0.0099 16.0 5.3 0.0099 16.0 5.3 2.0 2 0 0 2 2 2 1 PARM ER-remodelling PF14755.6 RUS82499.1 - 0.33 11.2 9.0 2 8.7 2.3 2.2 2 0 0 2 2 2 0 Intracellular membrane remodeller SUIM_assoc PF16619.5 RUS82501.1 - 0.016 15.3 8.8 0.016 15.3 8.8 3.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 HycA_repressor PF11046.8 RUS82501.1 - 0.12 12.5 2.3 0.27 11.4 2.3 1.4 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Rtf2 PF04641.12 RUS82505.1 - 0.0012 18.3 27.9 0.002 17.6 27.9 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Vfa1 PF08432.10 RUS82505.1 - 0.0015 18.9 28.3 0.0015 18.9 28.3 2.4 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.11 RUS82505.1 - 0.0062 16.0 15.0 0.0062 16.0 15.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) FAM76 PF16046.5 RUS82505.1 - 0.022 14.2 27.4 0.029 13.7 27.4 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2828 PF11443.8 RUS82505.1 - 0.18 9.9 21.5 0.24 9.5 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Sec62 PF03839.16 RUS82505.1 - 0.36 10.3 26.8 0.54 9.7 26.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 MDM10 PF12519.8 RUS82505.1 - 0.4 9.5 14.5 0.47 9.2 14.5 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FGF-BP1 PF06473.12 RUS82505.1 - 0.43 10.4 26.6 0.71 9.7 26.6 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) AF-4 PF05110.13 RUS82505.1 - 0.46 8.5 35.3 0.56 8.2 35.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RPOL_N PF14700.6 RUS82505.1 - 0.6 9.4 21.7 0.86 8.9 21.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF2126 PF09899.9 RUS82505.1 - 1.1 7.2 8.3 1.5 6.8 8.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Connexin PF00029.19 RUS82505.1 - 1.2 8.9 21.0 2.3 7.9 21.0 1.5 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 RUS82505.1 - 1.3 7.8 36.9 0.036 12.9 23.7 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SOBP PF15279.6 RUS82505.1 - 1.8 9.1 14.2 2.3 8.7 14.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4776 PF16003.5 RUS82505.1 - 2.4 7.1 28.8 3.5 6.5 28.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) CSG2 PF16965.5 RUS82505.1 - 3.2 6.6 6.8 4.6 6.1 6.8 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Cellulose_synt PF03552.14 RUS82505.1 - 3.6 6.0 13.6 5.1 5.5 13.6 1.3 1 0 0 1 1 1 0 Cellulose synthase Membralin PF09746.9 RUS82505.1 - 4.4 6.2 12.0 5.3 6.0 12.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein Peptidase_S64 PF08192.11 RUS82505.1 - 5.4 5.4 22.2 7.3 4.9 22.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 RUS82505.1 - 6.8 5.4 17.8 8.6 5.1 17.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Kei1 PF08552.11 RUS82505.1 - 7.1 6.5 5.6 9.3 6.1 5.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RNA_pol_Rpc4 PF05132.14 RUS82505.1 - 9.3 6.7 30.6 0.98 9.8 20.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 CLN3 PF02487.17 RUS82505.1 - 9.4 5.2 13.0 13 4.7 13.0 1.1 1 0 0 1 1 1 0 CLN3 protein zf-C2H2 PF00096.26 RUS82506.1 - 3.5e-26 90.2 52.3 3.4e-06 27.2 3.8 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS82506.1 - 3.5e-24 84.1 49.6 1.1e-07 31.9 1.5 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS82506.1 - 2.7e-22 77.5 50.4 0.00055 20.5 0.8 7.2 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 RUS82506.1 - 1.2e-08 35.0 42.6 0.022 15.1 2.6 7.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS82506.1 - 6.2e-07 29.5 37.1 0.0092 16.3 0.9 7.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS82506.1 - 0.0011 19.2 28.1 0.03 14.6 5.2 4.1 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 RUS82506.1 - 0.0057 16.7 30.2 1.3 9.2 2.2 6.4 5 2 0 5 5 5 2 Zinc ribbon domain C1_4 PF07975.12 RUS82506.1 - 0.0077 16.4 28.1 0.68 10.2 3.8 5.3 1 1 5 6 6 6 5 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 RUS82506.1 - 0.017 15.9 23.3 5.4 7.8 5.0 3.8 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_11 PF16622.5 RUS82506.1 - 0.02 14.6 33.8 0.25 11.1 0.0 7.1 7 0 0 7 7 7 0 zinc-finger C2H2-type XPA_N PF01286.18 RUS82506.1 - 0.026 14.6 27.9 0.066 13.3 0.2 6.8 7 0 0 7 7 7 0 XPA protein N-terminal zf-C2H2_6 PF13912.6 RUS82506.1 - 0.096 12.7 0.6 0.096 12.7 0.6 8.6 8 1 0 8 8 8 0 C2H2-type zinc finger GATA PF00320.27 RUS82506.1 - 0.17 11.5 0.3 0.17 11.5 0.3 4.6 6 0 0 6 6 6 0 GATA zinc finger zf-C2H2_2 PF12756.7 RUS82506.1 - 0.21 11.9 34.5 1.3 9.4 0.9 6.6 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RUS82506.1 - 0.43 10.8 36.1 0.86 9.8 10.3 4.0 1 1 1 2 2 2 0 FYVE zinc finger zf_UBZ PF18439.1 RUS82506.1 - 0.63 9.7 28.7 0.6 9.8 0.2 6.8 7 2 0 7 7 7 0 Ubiquitin-Binding Zinc Finger DUF4428 PF14471.6 RUS82506.1 - 0.96 9.4 0.0 0.96 9.4 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4428) zf-AN1 PF01428.16 RUS82506.1 - 1 9.6 39.2 3 8.1 0.2 7.0 4 1 2 6 6 6 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 RUS82506.1 - 3.9 7.5 31.4 2.1 8.3 0.3 6.2 6 0 0 6 6 5 0 zinc-finger of a C2HC-type MFS_1 PF07690.16 RUS82507.1 - 2.9e-32 112.0 23.9 3.5e-17 62.4 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS82507.1 - 1.8e-06 27.5 2.2 1.8e-06 27.5 2.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Fumble PF03630.14 RUS82508.1 - 7.5e-132 439.5 0.0 1e-131 439.1 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 RUS82508.1 - 7.3e-41 140.3 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF5016 PF16408.5 RUS82508.1 - 0.2 11.6 1.6 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5016) 7TM_GPCR_Srw PF10324.9 RUS82509.1 - 6.3e-14 52.0 17.1 1.5e-13 50.8 17.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS82509.1 - 7e-13 48.5 14.8 9.2e-13 48.1 14.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS82509.1 - 0.0039 16.8 11.9 0.0039 16.8 11.9 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Somatomedin_B PF01033.17 RUS82510.1 - 2.4e-05 24.6 14.6 5.8e-05 23.4 14.6 1.6 1 0 0 1 1 1 1 Somatomedin B domain Rab3-GTPase_cat PF13890.6 RUS82511.1 - 1.2e-63 213.6 0.0 5.7e-63 211.4 0.0 2.2 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Ead_Ea22 PF13935.6 RUS82512.1 - 4.7e-05 24.1 0.0 0.45 11.2 0.0 2.4 2 0 0 2 2 2 2 Ead/Ea22-like protein EF-hand_3 PF09069.11 RUS82512.1 - 5.7e-05 23.4 2.2 2.3 8.7 0.0 4.6 3 1 3 6 6 6 2 EF-hand Phage_tail_APC PF16778.5 RUS82512.1 - 0.011 15.6 0.1 12 5.9 0.0 3.4 2 1 0 2 2 2 0 Phage tail assembly chaperone protein ParcG PF10274.9 RUS82512.1 - 0.016 15.3 1.0 33 4.5 0.1 3.8 1 1 2 4 4 4 0 Parkin co-regulated protein RVT_1 PF00078.27 RUS82512.1 - 0.054 13.0 2.6 7.8 5.9 0.1 3.4 2 1 2 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) PET PF06297.14 RUS82512.1 - 0.21 11.9 2.8 40 4.6 0.1 4.2 1 1 4 6 6 6 0 PET Domain DDA1 PF10172.9 RUS82512.1 - 0.5 10.7 9.2 43 4.5 0.1 4.8 2 2 6 8 8 8 0 Det1 complexing ubiquitin ligase DUF1768 PF08719.11 RUS82512.1 - 0.98 9.6 13.6 1.8e+04 -5.4 13.6 5.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) LCE6A PF15858.5 RUS82512.1 - 3.7 8.4 7.0 45 4.9 0.0 3.4 4 0 0 4 4 4 0 Late cornified envelope protein 6A family KH_9 PF17904.1 RUS82513.1 - 7.6e-26 90.3 0.1 2.5e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 RUS82513.1 - 2e-19 69.2 0.9 4.4e-19 68.1 0.1 2.0 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 RUS82513.1 - 9.1e-14 51.0 1.5 2.1e-08 33.9 0.5 2.9 2 1 0 2 2 2 2 KH domain FXMRP1_C_core PF12235.8 RUS82513.1 - 4e-12 47.0 2.6 4e-12 47.0 2.6 4.0 1 1 2 3 3 3 2 Fragile X-related 1 protein core C terminal KH_2 PF07650.17 RUS82513.1 - 0.02 14.7 1.4 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 KH domain KH_4 PF13083.6 RUS82513.1 - 0.11 12.4 0.7 7.5 6.5 0.1 2.9 2 1 1 3 3 3 0 KH domain RP853 PF17542.2 RUS82516.1 - 0.0038 16.4 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized RP853 Ly49 PF08391.10 RUS82516.1 - 0.0039 17.5 0.1 0.007 16.7 0.1 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region DUF4199 PF13858.6 RUS82516.1 - 0.017 15.5 0.2 0.024 15.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) LRR19-TM PF15176.6 RUS82516.1 - 0.052 13.5 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Protocadherin PF08374.11 RUS82516.1 - 0.054 13.5 0.3 0.097 12.6 0.3 1.4 1 0 0 1 1 1 0 Protocadherin Sigma_reg_N PF13800.6 RUS82516.1 - 0.068 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Sugar_tr PF00083.24 RUS82516.1 - 0.1 11.4 0.7 0.14 11.0 0.7 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF2149 PF09919.9 RUS82516.1 - 0.18 12.1 2.1 0.4 11.0 2.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) AIG1 PF04548.16 RUS82517.1 - 4.2e-37 127.5 0.0 4.8e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS82517.1 - 6.1e-09 36.0 0.0 7.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RUS82517.1 - 0.013 15.6 0.7 4.1 7.4 0.2 2.5 2 1 0 3 3 3 0 Dynamin family Gtr1_RagA PF04670.12 RUS82517.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 RUS82517.1 - 0.079 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 RUS82517.1 - 0.097 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 RUS82517.1 - 0.13 12.3 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 RUS82517.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 RUS82517.1 - 0.18 11.7 0.4 0.42 10.5 0.4 1.6 1 1 0 1 1 1 0 RsgA GTPase Lambda_Kil PF06301.11 RUS82518.1 - 0.00072 19.1 0.9 0.0018 17.8 0.1 2.1 2 0 0 2 2 2 1 Bacteriophage lambda Kil protein TerY_C PF15616.6 RUS82518.1 - 0.0077 16.3 2.9 0.0079 16.3 0.7 1.9 1 1 1 2 2 2 1 TerY-C metal binding domain Wax2_C PF12076.8 RUS82518.1 - 0.057 13.1 0.9 0.099 12.4 0.9 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain TPR_11 PF13414.6 RUS82518.1 - 0.067 12.9 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 RUS82518.1 - 0.07 13.0 0.7 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3347 PF11827.8 RUS82518.1 - 0.64 10.2 9.5 0.92 9.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Phageshock_PspD PF09584.10 RUS82519.1 - 0.037 14.1 22.0 2.4 8.2 10.4 3.1 1 1 2 3 3 3 0 Phage shock protein PspD (Phageshock_PspD) COesterase PF00135.28 RUS82521.1 - 8e-100 335.1 0.0 1.2e-99 334.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS82521.1 - 1.4e-10 41.4 0.0 0.00024 21.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS82521.1 - 6.4e-05 23.7 0.1 0.00016 22.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RUS82521.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4527 PF15030.6 RUS82521.1 - 0.2 11.1 0.3 0.37 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) ARID PF01388.21 RUS82522.1 - 8.5e-22 77.6 0.5 4.1e-21 75.4 0.0 2.5 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 RUS82522.1 - 6.2e-09 36.4 0.3 1.8e-08 34.9 0.3 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 RUS82522.1 - 4.8 6.4 9.7 0.25 10.6 0.1 3.4 4 0 0 4 4 4 0 SWI/SNF-like complex subunit BAF250/Osa HSP70 PF00012.20 RUS82523.1 - 7.3e-256 850.1 1.8 8.3e-256 849.9 1.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS82523.1 - 8.7e-14 51.1 0.0 7.1e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 RUS82523.1 - 0.0007 20.0 0.5 11 6.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 RUS82523.1 - 0.0011 18.7 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M3_N PF08439.10 RUS82523.1 - 0.2 12.0 1.0 0.73 10.1 0.1 2.3 2 0 0 2 2 2 0 Oligopeptidase F Clusterin PF01093.17 RUS82523.1 - 0.89 8.5 4.5 0.95 8.4 0.3 2.4 3 0 0 3 3 3 0 Clusterin CTD_bind PF04818.13 RUS82524.1 - 1.9e-15 57.4 0.0 6.1e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 RUS82524.1 - 7.6e-10 38.5 0.0 2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS82524.1 - 0.0037 17.1 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Importin_rep_4 PF18808.1 RUS82524.1 - 0.034 14.4 3.3 0.19 12.0 3.3 2.3 1 0 0 1 1 1 0 Importin repeat RSRP PF17069.5 RUS82524.1 - 3.8 7.0 34.4 9.1 5.8 34.4 1.7 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SdpI PF13630.6 RUS82525.1 - 0.0059 16.7 0.3 0.47 10.6 0.0 2.8 2 1 0 2 2 2 1 SdpI/YhfL protein family Flp1_like PF16982.5 RUS82525.1 - 0.029 13.8 0.3 0.05 13.0 0.3 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF4131 PF13567.6 RUS82525.1 - 0.037 13.7 1.3 0.86 9.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TRP PF06011.12 RUS82525.1 - 0.041 12.6 0.6 0.074 11.8 0.1 1.6 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel TMEM156 PF15106.6 RUS82525.1 - 0.053 13.0 0.3 0.088 12.2 0.3 1.3 1 0 0 1 1 1 0 TMEM156 protein family EphA2_TM PF14575.6 RUS82525.1 - 0.18 12.7 0.2 20 6.1 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF347 PF03988.12 RUS82525.1 - 1.9 8.7 6.7 5.6 7.2 1.3 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) HemY_N PF07219.13 RUS82525.1 - 5.5 7.2 7.9 2.2 8.5 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus zf_Rg PF17915.1 RUS82526.1 - 4.3e-05 22.8 6.4 37 3.8 0.0 5.9 6 0 0 6 6 6 5 Reverse gyrase zinc finger Enolase_like_N PF18374.1 RUS82526.1 - 5.3 6.5 13.6 49 3.4 0.1 5.3 1 1 5 6 6 6 0 Enolase N-terminal domain-like MORN PF02493.20 RUS82526.1 - 6.8 6.8 29.5 17 5.5 0.9 5.6 5 0 0 5 5 5 0 MORN repeat CarbopepD_reg_2 PF13715.6 RUS82527.1 - 0.0034 17.3 0.6 1.7 8.7 0.1 2.4 1 1 1 2 2 2 2 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 RUS82527.1 - 0.0075 16.5 1.8 1.4 9.3 0.2 2.4 1 1 1 2 2 2 2 Carboxypeptidase regulatory-like domain P_proprotein PF01483.20 RUS82527.1 - 0.033 14.2 0.0 9.1 6.4 0.0 2.2 1 1 1 2 2 2 0 Proprotein convertase P-domain SecG PF03840.14 RUS82527.1 - 0.035 14.2 0.1 8.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit MBG PF17883.1 RUS82527.1 - 0.063 13.9 0.3 2.9 8.5 0.3 2.2 1 1 0 1 1 1 0 MBG domain Anoct_dimer PF16178.5 RUS82527.1 - 0.1 12.3 0.1 3.9 7.1 0.0 2.0 1 1 1 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Cadherin_C_2 PF16492.5 RUS82527.1 - 0.21 12.4 2.4 8.9 7.1 0.1 2.1 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal EMP70 PF02990.16 RUS82528.1 - 0.062 12.0 0.1 0.093 11.4 0.1 1.3 1 1 0 1 1 1 0 Endomembrane protein 70 7tm_2 PF00002.24 RUS82530.1 - 3.5e-31 108.4 13.3 5.5e-16 58.6 2.7 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) BUD22 PF09073.10 RUS82530.1 - 2.9e-10 40.1 32.0 3.7e-10 39.7 32.0 1.2 1 0 0 1 1 1 1 BUD22 CobT PF06213.12 RUS82530.1 - 0.0016 17.9 31.9 0.0016 17.9 31.9 2.1 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Serinc PF03348.15 RUS82530.1 - 0.0017 17.4 0.1 0.0017 17.4 0.1 3.0 3 0 0 3 3 2 1 Serine incorporator (Serinc) RNA_pol_Rpc4 PF05132.14 RUS82530.1 - 0.0024 18.3 5.7 0.0024 18.3 5.7 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 RRN3 PF05327.11 RUS82530.1 - 0.0033 16.0 7.5 0.0033 16.0 7.5 2.2 2 0 0 2 2 1 1 RNA polymerase I specific transcription initiation factor RRN3 RPN2_C PF18004.1 RUS82530.1 - 0.0071 16.3 26.1 0.0071 16.3 26.1 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF789 PF05623.12 RUS82530.1 - 0.0082 15.9 2.5 0.0082 15.9 2.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF789) PIP5K PF01504.18 RUS82530.1 - 0.021 14.1 0.1 0.021 14.1 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase SRP-alpha_N PF04086.13 RUS82530.1 - 1.4 8.8 27.4 1.9 8.4 27.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SLC12 PF03522.15 RUS82530.1 - 1.5 7.7 19.4 2 7.3 19.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FYDLN_acid PF09538.10 RUS82530.1 - 2.4 8.9 48.0 0.35 11.6 22.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Afi1 PF07792.12 RUS82530.1 - 3.2 8.3 37.6 0.082 13.4 12.7 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPP4R2 PF09184.11 RUS82530.1 - 8.6 5.9 53.5 0.072 12.7 27.5 2.2 2 0 0 2 2 2 0 PPP4R2 Arf PF00025.21 RUS82531.1 - 4.1e-65 218.5 0.4 4.9e-65 218.2 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS82531.1 - 3.4e-16 59.5 0.3 4.8e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS82531.1 - 6.4e-14 51.9 0.1 6.9e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS82531.1 - 1.7e-13 50.4 0.0 2.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS82531.1 - 7.3e-08 31.9 0.3 0.00022 20.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RUS82531.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS82531.1 - 2.1e-07 30.5 0.1 2.5e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS82531.1 - 0.013 15.1 0.1 0.19 11.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 RUS82531.1 - 0.028 14.4 0.1 0.049 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 RUS82531.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 RUS82531.1 - 0.14 11.7 0.5 0.74 9.3 0.5 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Pcc1 PF09341.10 RUS82532.1 - 2.3e-25 88.5 0.0 2.6e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Tim44 PF04280.15 RUS82534.1 - 1.9e-42 144.8 0.0 1.9e-42 144.8 0.0 2.2 2 1 0 2 2 2 1 Tim44-like domain ApoLp-III PF07464.11 RUS82534.1 - 0.55 10.3 19.3 5.6 7.0 19.4 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3347 PF11827.8 RUS82534.1 - 3.6 7.7 18.2 4.3 7.5 7.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) UPF0242 PF06785.11 RUS82535.1 - 0.0015 18.6 3.2 0.0019 18.3 3.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus GPI2 PF06432.11 RUS82535.1 - 0.0028 17.1 0.1 0.0035 16.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Kinesin PF00225.23 RUS82536.1 - 2.3e-106 355.5 0.2 4.1e-106 354.7 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS82536.1 - 5.2e-20 71.9 0.1 4.3e-19 68.9 0.1 2.5 1 1 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 RUS82536.1 - 2.6e-11 43.8 2.9 4e-10 40.0 0.2 2.8 2 0 0 2 2 2 1 Kinesin protein 1B Kinesin_assoc PF16183.5 RUS82536.1 - 1.1e-06 29.0 8.7 1.2e-05 25.5 0.9 3.9 3 1 1 4 4 4 2 Kinesin-associated FHA PF00498.26 RUS82536.1 - 5.3e-05 23.5 0.1 0.00014 22.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain C2-C2_1 PF11618.8 RUS82536.1 - 0.007 16.4 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 XH PF03469.14 RUS82536.1 - 0.044 13.7 4.4 0.06 13.3 0.9 2.8 3 0 0 3 3 3 0 XH domain Yop-YscD_cpl PF16697.5 RUS82536.1 - 0.049 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF3824 PF12868.7 RUS82536.1 - 0.13 13.0 3.2 0.32 11.6 3.2 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AAA_32 PF13654.6 RUS82536.1 - 0.13 11.0 7.0 0.035 12.9 2.0 2.3 3 0 0 3 3 3 0 AAA domain Ribosomal_60s PF00428.19 RUS82536.1 - 0.23 12.0 16.6 1.2 9.8 2.8 3.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF87 PF01935.17 RUS82536.1 - 0.54 10.3 3.1 30 4.6 0.3 3.1 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_pol_3_Rpc31 PF11705.8 RUS82537.1 - 0.0013 19.0 14.2 0.0013 19.0 14.2 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2201_N PF13203.6 RUS82537.1 - 0.0037 16.9 5.8 0.0037 16.9 5.8 1.7 1 1 0 2 2 2 1 Putative metallopeptidase domain PBP_sp32 PF07222.12 RUS82537.1 - 0.03 13.8 11.3 0.05 13.1 11.3 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Myc_N PF01056.18 RUS82537.1 - 0.038 13.9 13.0 0.34 10.8 6.5 2.2 2 0 0 2 2 2 0 Myc amino-terminal region MCM_bind PF09739.9 RUS82537.1 - 0.12 10.8 11.8 0.17 10.3 11.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF1096 PF06493.11 RUS82537.1 - 0.28 11.7 3.5 0.66 10.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1096) TFIIF_alpha PF05793.12 RUS82537.1 - 0.49 8.9 40.0 0.46 9.0 1.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 RUS82537.1 - 0.75 9.1 30.0 0.14 11.5 22.8 2.1 2 0 0 2 2 2 0 BUD22 Nucleo_P87 PF07267.11 RUS82537.1 - 1.2 7.9 13.4 0.052 12.4 8.5 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF2828 PF11443.8 RUS82537.1 - 2.4 6.1 13.4 3 5.8 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PTPRCAP PF15713.5 RUS82537.1 - 3.2 8.0 20.4 1.1 9.6 14.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Ureide_permease PF07168.11 RUS82537.1 - 5.1 5.7 5.8 7.4 5.2 5.8 1.2 1 0 0 1 1 1 0 Ureide permease Cellulose_synt PF03552.14 RUS82537.1 - 6.7 5.1 8.2 9.2 4.6 8.2 1.2 1 0 0 1 1 1 0 Cellulose synthase V_ATPase_I PF01496.19 RUS82537.1 - 6.9 4.5 11.5 9.2 4.0 11.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1945 PF09178.10 RUS82539.1 - 0.053 13.7 3.3 6.9 7.0 0.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1945) 7TM_GPCR_Srw PF10324.9 RUS82540.1 - 3.2e-42 144.9 21.3 3.9e-42 144.7 21.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS82540.1 - 3.8e-13 49.4 19.2 6.5e-13 48.6 19.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRIMA1 PF16101.5 RUS82540.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.7 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 RVT_1 PF00078.27 RUS82542.1 - 5.1e-17 62.1 0.0 6.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 RUS82542.1 - 4.1e-05 23.4 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like TPR_19 PF14559.6 RUS82543.1 - 3.4e-21 75.5 14.7 2.5e-06 27.9 2.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS82543.1 - 7.6e-13 48.5 25.6 4e-07 30.2 0.1 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RUS82543.1 - 1.8e-07 31.7 0.8 0.011 16.4 0.0 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS82543.1 - 2.2e-07 30.4 30.2 0.0061 16.6 0.2 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS82543.1 - 2.9e-07 30.7 10.1 0.0054 17.3 0.1 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS82543.1 - 1.8e-06 28.3 5.8 1.9 9.5 0.0 6.2 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS82543.1 - 3.8e-06 26.5 6.8 0.2 11.8 0.3 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS82543.1 - 1.2e-05 25.4 0.2 0.33 11.1 0.6 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS82543.1 - 0.00018 21.2 21.9 0.69 9.8 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS82543.1 - 0.00023 21.1 7.8 0.046 13.9 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS82543.1 - 0.0019 18.4 14.5 1.3 9.4 0.1 5.7 6 2 1 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 RUS82543.1 - 0.049 13.9 0.6 54 4.3 0.0 4.4 5 0 0 5 5 4 0 PPR repeat Drf_FH3 PF06367.16 RUS82543.1 - 0.066 12.8 1.5 13 5.4 0.1 3.2 3 0 0 3 3 3 0 Diaphanous FH3 Domain PyocinActivator PF11112.8 RUS82543.1 - 0.071 13.2 1.0 0.77 9.9 0.2 2.7 2 0 0 2 2 2 0 Pyocin activator protein PrtN PriA_C PF18074.1 RUS82543.1 - 0.088 13.6 0.4 21 6.0 0.0 3.2 3 0 0 3 3 3 0 Primosomal protein N C-terminal domain TPR_17 PF13431.6 RUS82543.1 - 0.5 10.9 13.1 0.93 10.0 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS82543.1 - 1.4 8.8 10.9 23 5.0 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 RUS82544.1 - 4.5e-18 65.8 0.1 5.9e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS82544.1 - 1.6e-07 30.8 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 HSP70 PF00012.20 RUS82545.1 - 6.3e-161 536.6 1.3 7.2e-161 536.4 1.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS82545.1 - 3.8e-07 29.3 0.0 5.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RUS82545.1 - 0.00016 21.5 0.0 0.00085 19.1 0.0 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 RUS82546.1 - 8.2e-68 229.0 0.1 9.2e-68 228.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF1441 PF07278.11 RUS82547.1 - 0.0066 16.4 0.2 0.016 15.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1441) MIT PF04212.18 RUS82547.1 - 3.2 7.9 6.5 1.6 8.9 3.6 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain HlyIII PF03006.20 RUS82548.1 - 6.2e-35 120.9 25.2 7.5e-35 120.7 25.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related EF-hand_6 PF13405.6 RUS82549.1 - 5.2e-20 69.6 2.7 4.5e-05 23.0 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 RUS82549.1 - 1e-19 68.5 8.1 7.3e-05 22.1 0.2 5.6 5 1 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 RUS82549.1 - 3e-19 69.2 0.3 2e-08 34.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS82549.1 - 4.4e-17 60.7 3.7 3.6e-05 23.1 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS82549.1 - 4.6e-15 55.2 0.4 2.8e-09 36.7 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair EAP30 PF04157.16 RUS82549.1 - 0.094 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family DUF3432 PF11914.8 RUS82549.1 - 0.44 10.8 4.3 1.3 9.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) MADF_DNA_bdg PF10545.9 RUS82551.1 - 6.7e-19 68.0 3.5 6.7e-19 68.0 3.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS82551.1 - 4e-05 23.3 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 BESS motif DUF1770 PF08589.10 RUS82551.1 - 0.066 14.2 0.1 0.14 13.1 0.1 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Peptidase_C14 PF00656.22 RUS82552.1 - 1.8e-44 152.6 0.0 2.2e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Transposase_1 PF01359.18 RUS82553.1 - 8.3e-18 64.0 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS82553.1 - 2e-07 30.9 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 RUS82553.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 RUS82553.1 - 0.0058 17.2 0.3 0.016 15.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DUF4817 PF16087.5 RUS82553.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) 60KD_IMP PF02096.20 RUS82554.1 - 5e-18 65.5 0.8 2.5e-17 63.3 0.8 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Lipoprotein_7 PF01540.16 RUS82554.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Cadherin PF00028.17 RUS82555.1 - 0 1256.5 150.9 7.5e-17 61.6 0.1 52.9 53 0 0 53 53 53 50 Cadherin domain Y_Y_Y PF07495.13 RUS82555.1 - 5.3e-07 29.5 6.2 65 3.6 0.0 14.6 19 0 0 19 19 19 0 Y_Y_Y domain PepSY PF03413.19 RUS82555.1 - 0.00015 22.2 16.4 2.1 8.9 0.0 12.5 13 0 0 13 13 13 1 Peptidase propeptide and YPEB domain Cadherin_pro PF08758.11 RUS82555.1 - 0.00096 19.3 0.1 23 5.2 0.0 7.5 9 0 0 9 9 9 1 Cadherin prodomain like Cadherin PF00028.17 RUS82556.1 - 2.5e-12 47.1 0.2 4.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Cadherin domain DUF3093 PF11292.8 RUS82556.1 - 0.16 12.3 0.2 0.3 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) HCV_NS4a PF01006.20 RUS82558.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Coilin_N PF15862.5 RUS82560.1 - 1.5e-05 24.8 0.0 6.3 6.6 0.0 3.2 3 1 0 3 3 3 2 Coilin N-terminus Claudin_2 PF13903.6 RUS82561.1 - 4.3e-26 91.9 0.1 6.3e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS82561.1 - 1.2e-06 28.5 7.0 0.00028 20.8 7.0 3.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 RUS82561.1 - 0.076 12.6 10.4 0.86 9.2 10.9 2.4 1 1 0 1 1 1 0 SUR7/PalI family DUF2721 PF11026.8 RUS82561.1 - 1.9 8.4 5.8 0.21 11.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SNARE_assoc PF09335.11 RUS82561.1 - 2.4 8.7 10.5 3.5 8.2 0.1 3.0 2 1 2 4 4 4 0 SNARE associated Golgi protein Glyco_transf_22 PF03901.17 RUS82562.1 - 3e-50 171.7 22.7 3.5e-50 171.4 22.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pox_A14 PF05767.12 RUS82562.1 - 2.4 8.4 7.2 0.98 9.6 0.1 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 LLC1 PF14945.6 RUS82563.1 - 0.011 16.3 0.1 0.014 16.0 0.1 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein ERCC4 PF02732.15 RUS82564.1 - 3e-05 24.3 1.1 6.5e-05 23.2 0.6 1.7 2 0 0 2 2 2 1 ERCC4 domain UPF0154 PF03672.13 RUS82565.1 - 0.083 12.9 0.7 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) bZIP_Maf PF03131.17 RUS82566.1 - 9e-31 106.3 10.7 1.2e-30 105.8 10.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor FapA PF03961.13 RUS82566.1 - 0.00011 21.0 1.2 0.00012 20.8 1.2 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF2046 PF09755.9 RUS82566.1 - 0.00055 19.3 2.6 0.00055 19.3 2.6 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 RUS82566.1 - 0.0021 17.8 3.4 0.0021 17.8 3.4 2.1 1 1 1 2 2 2 1 Septum formation initiator JIP_LZII PF16471.5 RUS82566.1 - 0.0023 18.0 3.3 0.0023 18.0 3.3 2.2 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 RUS82566.1 - 0.012 15.7 16.7 0.012 15.7 16.7 2.2 2 1 0 2 2 1 0 bZIP transcription factor GPS2_interact PF15784.5 RUS82566.1 - 0.018 15.5 1.9 0.018 15.5 1.9 2.4 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF1192 PF06698.11 RUS82566.1 - 0.02 14.9 1.3 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Prominin PF05478.11 RUS82566.1 - 0.1 10.6 1.4 0.11 10.4 1.4 1.0 1 0 0 1 1 1 0 Prominin bZIP_2 PF07716.15 RUS82566.1 - 0.11 12.6 19.4 0.36 11.0 16.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF2968 PF11180.8 RUS82566.1 - 0.12 12.0 3.8 0.23 11.1 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) FtsL PF04999.13 RUS82566.1 - 0.15 12.1 2.0 0.29 11.2 2.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsL Spc7 PF08317.11 RUS82566.1 - 0.2 10.5 6.9 0.31 9.9 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.18 RUS82566.1 - 0.3 11.3 8.1 0.088 13.0 3.2 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 RUS82566.1 - 0.32 11.5 11.8 19 5.8 11.8 2.4 1 1 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 RUS82566.1 - 0.48 11.0 11.0 1 9.9 10.9 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Tox-ODYAM1 PF15642.6 RUS82566.1 - 0.53 9.2 3.1 0.64 8.9 3.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus NUDE_C PF04880.13 RUS82566.1 - 0.54 10.7 11.1 0.071 13.6 4.4 2.0 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region DUF4191 PF13829.6 RUS82566.1 - 0.95 8.8 3.6 4.6 6.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Fzo_mitofusin PF04799.13 RUS82566.1 - 1.4 8.4 4.4 2.2 7.8 4.0 1.5 1 1 0 1 1 1 0 fzo-like conserved region MCU PF04678.13 RUS82566.1 - 4.9 7.2 5.1 5.3 7.1 4.3 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter 7tm_1 PF00001.21 RUS82569.1 - 1.3e-12 47.6 18.4 1.2e-11 44.4 18.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srb PF02175.16 RUS82569.1 - 0.0044 16.8 4.2 0.048 13.4 0.4 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srb BatD PF13584.6 RUS82569.1 - 0.027 13.3 0.0 0.075 11.8 0.0 1.6 2 0 0 2 2 2 0 Oxygen tolerance DUF2208 PF09973.9 RUS82569.1 - 0.55 9.8 12.6 0.6 9.7 3.3 2.7 2 2 0 2 2 2 0 Predicted membrane protein (DUF2208) F-box_5 PF18511.1 RUS82570.1 - 1.1 8.9 18.0 1.8e+04 -10.6 18.0 6.4 1 1 0 1 1 1 0 F-box Xpo1 PF08389.12 RUS82570.1 - 3.5 7.7 7.1 8 6.5 2.2 2.0 1 1 1 2 2 2 0 Exportin 1-like protein IMCp PF12314.8 RUS82570.1 - 5.4 7.4 15.2 14 6.0 15.2 1.8 1 1 0 1 1 1 0 Inner membrane complex protein HTH_29 PF13551.6 RUS82570.1 - 7.8 6.6 14.3 1.8e+04 -6.5 14.3 4.5 1 1 0 1 1 1 0 Winged helix-turn helix DUF4573 PF15140.6 RUS82571.1 - 0.0025 17.6 0.1 0.0036 17.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Tcp10_C PF07202.13 RUS82571.1 - 0.05 13.6 0.0 0.075 13.0 0.0 1.5 1 1 0 1 1 1 0 T-complex protein 10 C-terminus 7tm_1 PF00001.21 RUS82572.1 - 5.9e-17 61.8 13.7 7.7e-17 61.5 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82572.1 - 2.2e-11 43.7 14.5 4.8e-11 42.5 14.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS82572.1 - 3.7e-08 33.3 12.5 3.7e-08 33.3 12.5 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS82572.1 - 0.021 14.6 10.4 0.03 14.1 10.4 1.3 1 0 0 1 1 1 0 Olfactory receptor Mpp10 PF04006.12 RUS82573.1 - 1.6e-05 23.6 12.3 2.1e-05 23.2 12.3 1.2 1 0 0 1 1 1 1 Mpp10 protein NOA36 PF06524.12 RUS82573.1 - 0.00015 21.2 36.0 0.00021 20.7 36.0 1.2 1 0 0 1 1 1 1 NOA36 protein Nop14 PF04147.12 RUS82573.1 - 0.0047 15.2 28.2 0.0057 14.9 28.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS82573.1 - 0.01 15.3 27.5 0.012 15.0 27.5 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RUS82573.1 - 0.012 15.2 22.9 0.015 14.9 22.9 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 RUS82573.1 - 0.016 13.6 21.3 0.018 13.4 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RUS82573.1 - 0.13 11.0 9.0 0.14 10.9 9.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 RUS82573.1 - 0.16 10.9 1.9 0.19 10.6 1.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 RUS82573.1 - 0.84 8.4 8.2 1 8.1 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 RUS82573.1 - 1.6 7.2 27.0 2.7 6.4 27.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Collagen PF01391.18 RUS82574.1 - 6.3e-06 25.9 0.8 0.00017 21.3 0.3 2.7 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) L27 PF02828.16 RUS82574.1 - 0.36 10.6 3.1 14 5.6 0.0 4.5 3 2 0 3 3 3 0 L27 domain 7tm_1 PF00001.21 RUS82575.1 - 8.5e-16 58.1 11.3 1.1e-15 57.7 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82575.1 - 1.4e-09 37.7 12.6 3.9e-09 36.2 12.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS82575.1 - 0.00013 21.7 1.7 0.00013 21.7 1.7 2.9 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS82575.1 - 0.0005 19.9 4.4 0.00058 19.7 3.9 1.4 1 1 0 1 1 1 1 Olfactory receptor DUF898 PF05987.13 RUS82575.1 - 0.0021 17.2 1.9 0.0021 17.2 1.9 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF4201 PF13870.6 RUS82576.1 - 0.015 15.0 8.3 0.022 14.5 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HALZ PF02183.18 RUS82576.1 - 0.016 15.4 1.4 2.6 8.4 0.4 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Exonuc_VII_L PF02601.15 RUS82576.1 - 1.2 8.7 6.5 1.2 8.7 6.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4472 PF14739.6 RUS82576.1 - 2.1 9.1 11.5 14 6.5 11.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF3552 PF12072.8 RUS82576.1 - 3.5 7.0 9.2 3.8 6.9 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSP_1 PF00090.19 RUS82577.1 - 2.4e-06 27.6 7.3 2.4e-06 27.6 7.3 4.0 3 2 0 3 3 3 2 Thrombospondin type 1 domain PLAC PF08686.11 RUS82577.1 - 0.066 14.0 10.8 0.066 14.0 10.8 2.6 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain ADAM_spacer1 PF05986.14 RUS82578.1 - 1.5e-17 63.7 0.0 2.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 RUS82578.1 - 0.00023 21.3 9.0 0.00023 21.3 9.0 10.5 7 6 0 8 8 8 6 Thrombospondin type 1 domain DAGK_cat PF00781.24 RUS82578.1 - 0.0024 17.5 0.1 0.014 15.0 0.0 2.2 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain Reprolysin PF01421.19 RUS82579.1 - 4e-19 69.3 0.0 7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 RUS82579.1 - 1e-15 58.2 0.0 1.6e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 RUS82579.1 - 1.6e-12 47.7 3.4 4.8e-12 46.2 3.4 1.8 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RUS82579.1 - 1.5e-11 44.8 0.0 3.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS82579.1 - 3.9e-10 40.2 0.0 7.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 RUS82579.1 - 3.3e-09 36.7 1.2 1.5e-08 34.5 1.2 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS82579.1 - 3e-06 27.3 0.0 6.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SprT-like PF10263.9 RUS82579.1 - 0.00057 19.7 1.0 0.0013 18.6 1.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M10 PF00413.24 RUS82579.1 - 0.048 13.5 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Matrixin PTR2 PF00854.21 RUS82580.1 - 7.6e-91 304.9 10.8 2.1e-90 303.4 10.8 1.7 1 1 0 1 1 1 1 POT family Nop14 PF04147.12 RUS82581.1 - 0.11 10.7 23.7 0.14 10.4 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS82581.1 - 0.49 9.8 23.0 0.64 9.4 23.0 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS82581.1 - 0.61 8.1 40.0 0.81 7.7 40.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS82581.1 - 0.65 8.2 18.1 0.84 7.9 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PTR2 PF00854.21 RUS82582.1 - 7.5e-28 97.5 0.0 9.5e-23 80.7 0.0 2.5 3 0 0 3 3 3 2 POT family VirB3 PF05101.13 RUS82582.1 - 0.47 10.7 2.8 7.4 6.9 0.1 2.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein PTR2 PF00854.21 RUS82583.1 - 9.1e-40 136.7 0.5 1.3e-39 136.2 0.5 1.2 1 0 0 1 1 1 1 POT family Pkinase PF00069.25 RUS82584.1 - 8.8e-71 238.4 0.0 1.4e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82584.1 - 1.7e-39 135.7 0.0 3.4e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 RUS82584.1 - 1.8e-34 117.7 4.0 5.3e-17 61.8 0.0 4.2 4 0 0 4 4 4 2 POLO box duplicated region Pkinase_fungal PF17667.1 RUS82584.1 - 1.3e-07 30.8 0.8 1.3e-06 27.5 1.5 2.1 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS82584.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4524 PF15025.6 RUS82584.1 - 0.11 12.2 0.0 0.41 10.4 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) APH PF01636.23 RUS82584.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.13 RUS82584.1 - 1.9 8.4 11.7 2.7 7.9 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH2 PF00017.24 RUS82585.1 - 1.9e-26 91.9 0.0 1.2e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Somatomedin_B PF01033.17 RUS82586.1 - 0.00065 20.0 9.9 0.00065 20.0 9.9 2.1 2 0 0 2 2 2 1 Somatomedin B domain CAP PF00188.26 RUS82587.1 - 1.4e-11 45.3 6.5 1.8e-11 45.0 3.2 2.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ShK PF01549.24 RUS82587.1 - 3.5e-06 27.5 16.5 0.001 19.6 9.0 3.0 2 0 0 2 2 2 2 ShK domain-like Rhodanese PF00581.20 RUS82588.1 - 2.2e-29 102.1 0.0 1.6e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain MmgE_PrpD PF03972.14 RUS82589.1 - 1.8e-109 366.2 0.3 2.5e-109 365.7 0.3 1.2 1 0 0 1 1 1 1 MmgE/PrpD family Dmrt1 PF12374.8 RUS82589.1 - 1.6 9.2 7.9 5.2 7.6 1.2 4.4 4 1 0 4 4 4 0 Double-sex mab3 related transcription factor 1 UPAR_LY6 PF00021.21 RUS82590.1 - 0.051 14.3 16.8 0.082 13.6 16.8 1.4 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Sua5_yciO_yrdC PF01300.18 RUS82591.1 - 3.5e-23 82.0 0.0 5.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Trp_oprn_chp PF09534.10 RUS82591.1 - 3.8 7.3 15.1 0.13 12.1 7.9 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sua5_yciO_yrdC PF01300.18 RUS82592.1 - 6.4e-30 104.0 0.0 1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Gpr1_Fun34_YaaH PF01184.19 RUS82592.1 - 3.3e-06 26.9 13.2 3.3e-06 26.9 13.2 3.4 3 1 1 4 4 4 1 GPR1/FUN34/yaaH family Glyoxalase PF00903.25 RUS82593.1 - 2.3e-11 44.0 0.0 1e-10 41.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 RUS82593.1 - 0.00024 21.0 0.0 0.00076 19.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 RUS82593.1 - 0.0016 18.6 0.1 0.0031 17.6 0.1 1.5 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 RUS82593.1 - 0.0053 17.0 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 RUS82593.1 - 0.081 13.7 0.0 0.27 12.0 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain RVT_1 PF00078.27 RUS82594.1 - 1.7e-19 70.2 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mpv17_PMP22 PF04117.12 RUS82595.1 - 2.1e-25 88.7 1.1 3.4e-25 88.1 1.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1359 PF07097.11 RUS82596.1 - 0.027 14.7 0.2 0.043 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Ank_2 PF12796.7 RUS82597.1 - 1.1e-20 74.0 2.1 2.8e-10 40.6 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS82597.1 - 9.4e-13 48.1 0.6 0.00013 22.2 0.3 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS82597.1 - 3.9e-10 40.0 0.3 0.00022 21.7 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS82597.1 - 1.8e-08 34.5 3.7 0.0096 16.3 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 RUS82597.1 - 2.1e-07 30.7 0.3 0.54 11.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat adh_short PF00106.25 RUS82598.1 - 6.7e-09 35.5 0.0 9.4e-05 21.9 0.0 2.3 1 1 2 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82598.1 - 0.00056 19.5 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TMEM154 PF15102.6 RUS82599.1 - 0.00014 21.8 1.6 0.00014 21.8 1.6 2.8 3 0 0 3 3 3 1 TMEM154 protein family Orf78 PF06024.12 RUS82599.1 - 0.00081 19.6 0.2 0.0019 18.4 0.2 1.6 1 0 0 1 1 1 1 Orf78 (ac78) DUF4711 PF15829.5 RUS82599.1 - 0.0021 18.0 2.3 0.0037 17.2 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) RIFIN PF02009.16 RUS82599.1 - 0.0023 17.9 1.9 0.0036 17.3 1.9 1.3 1 0 0 1 1 1 1 Rifin Rax2 PF12768.7 RUS82599.1 - 0.0064 16.0 4.8 0.0091 15.5 0.3 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Amnionless PF14828.6 RUS82599.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF5527 PF17665.1 RUS82599.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF3377 PF11857.8 RUS82599.1 - 0.065 13.2 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CD34_antigen PF06365.12 RUS82599.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Peptidase_M56 PF05569.11 RUS82599.1 - 0.13 11.4 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.6 RUS82599.1 - 0.14 13.0 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sigma_reg_N PF13800.6 RUS82599.1 - 0.21 11.9 3.5 0.3 11.4 1.4 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Insulin_TMD PF17870.1 RUS82599.1 - 1.5 8.9 8.7 4.6 7.4 8.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 RUS82599.1 - 4.2 7.4 8.5 9.9 6.2 8.5 1.6 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 RUS82599.1 - 4.6 6.7 7.7 4 6.9 6.2 1.6 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame OAF PF14941.6 RUS82600.1 - 4.3e-49 167.2 2.3 4.9e-49 167.0 2.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first cNMP_binding PF00027.29 RUS82602.1 - 8.8e-20 70.6 0.0 1.3e-10 41.1 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain LRR_6 PF13516.6 RUS82603.1 - 4e-12 45.1 20.6 0.61 10.3 0.1 11.3 13 1 0 13 13 13 5 Leucine Rich repeat LRR_4 PF12799.7 RUS82603.1 - 9.2e-10 38.6 13.0 0.2 12.1 1.2 7.8 7 0 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS82603.1 - 0.00026 20.7 8.8 4 7.3 0.3 6.1 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 RUS82603.1 - 0.0021 18.3 20.7 6.8 7.7 0.5 9.5 9 1 0 9 9 9 1 Leucine Rich Repeat YdjM PF04307.14 RUS82604.1 - 1.4e-07 31.0 6.1 2.2e-07 30.4 6.1 1.3 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase RT_RNaseH PF17917.1 RUS82605.1 - 9.2e-30 103.0 0.0 2.2e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS82605.1 - 1.9e-28 98.4 0.0 4.2e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS82605.1 - 1.7e-20 73.5 0.2 8.9e-20 71.2 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS82605.1 - 8.8e-17 61.0 0.3 8.8e-17 61.0 0.3 2.0 2 0 0 2 2 1 1 Integrase zinc binding domain rve PF00665.26 RUS82605.1 - 3.4e-12 46.6 0.0 1.9e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 RUS82605.1 - 3.5e-05 24.3 0.0 7.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 RUS82605.1 - 0.0078 16.4 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 RUS82605.1 - 0.014 16.0 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 RUS82605.1 - 0.02 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3137 PF11335.8 RUS82605.1 - 0.066 13.2 0.1 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) RVP_2 PF08284.11 RUS82605.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease AMOP PF03782.17 RUS82606.1 - 8.7e-49 165.3 6.8 1.9e-48 164.2 6.8 1.6 1 0 0 1 1 1 1 AMOP domain NIDO PF06119.14 RUS82606.1 - 0.0024 18.8 0.0 0.0077 17.2 0.0 1.9 1 0 0 1 1 1 1 Nidogen-like VWD PF00094.25 RUS82606.1 - 0.021 15.1 0.2 0.084 13.1 0.1 2.0 2 0 0 2 2 2 0 von Willebrand factor type D domain LRR_6 PF13516.6 RUS82607.1 - 1.3e-13 49.8 18.1 0.014 15.4 0.0 8.2 8 0 0 8 8 8 4 Leucine Rich repeat EF-hand_6 PF13405.6 RUS82607.1 - 8.6e-10 37.8 0.5 0.0026 17.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS82607.1 - 1.2e-09 37.2 1.9 2e-05 23.8 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS82607.1 - 1.1e-06 29.0 4.5 0.039 14.4 1.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS82607.1 - 3e-06 26.4 7.8 0.0042 16.5 0.1 3.1 3 0 0 3 3 3 2 EF hand LRR_1 PF00560.33 RUS82607.1 - 0.00017 21.6 15.8 1.4 9.7 0.0 7.3 6 1 0 6 6 6 1 Leucine Rich Repeat Zw10 PF06248.13 RUS82607.1 - 0.031 12.9 0.2 0.049 12.2 0.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 LRR_8 PF13855.6 RUS82607.1 - 4.6 7.1 16.4 4.1 7.3 0.3 5.7 6 1 0 6 6 6 0 Leucine rich repeat LRR_4 PF12799.7 RUS82607.1 - 7.8 7.1 25.5 3.7 8.1 0.2 6.2 3 2 4 7 7 7 0 Leucine Rich repeats (2 copies) zf-rbx1 PF12678.7 RUS82608.1 - 3e-25 88.3 13.0 4.1e-25 87.8 13.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RUS82608.1 - 1.4e-17 63.6 10.0 1.8e-17 63.2 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RUS82608.1 - 1.7e-06 28.3 14.8 6.6e-05 23.2 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS82608.1 - 5.5e-05 22.9 3.3 5.5e-05 22.9 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82608.1 - 0.00094 19.0 12.1 0.015 15.2 12.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS82608.1 - 0.13 12.2 11.2 0.4 10.6 4.8 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS82608.1 - 0.2 11.5 15.7 19 5.1 15.7 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 RUS82608.1 - 0.22 11.8 9.2 1.2 9.4 9.4 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RUS82608.1 - 0.3 10.8 15.2 44 3.8 15.2 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 RUS82608.1 - 0.83 9.7 8.3 3.1 7.9 8.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger CDC13_N PF16853.5 RUS82609.1 - 0.088 12.3 4.1 0.12 11.9 4.1 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus Peptidase_S64 PF08192.11 RUS82609.1 - 1.7 7.0 15.7 2.1 6.8 15.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 F-box-like PF12937.7 RUS82611.1 - 3.2e-10 39.7 1.7 4.9e-10 39.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS82611.1 - 2.4e-08 33.6 0.9 2.4e-08 33.6 0.9 2.3 2 0 0 2 2 2 1 F-box domain APG17 PF04108.12 RUS82611.1 - 0.02 14.1 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Exo_endo_phos_2 PF14529.6 RUS82612.1 - 0.037 13.9 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Cytochrom_B561 PF03188.16 RUS82613.1 - 4e-10 40.0 3.6 4e-10 40.0 3.6 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 RUS82613.1 - 0.0037 17.2 2.7 0.1 12.5 0.5 2.8 2 1 1 3 3 3 1 Tight junction protein, Claudin-like GAS PF13851.6 RUS82614.1 - 4.3e-06 26.2 15.8 0.015 14.7 3.2 3.0 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 RUS82614.1 - 0.00016 22.0 9.2 0.29 11.4 0.6 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 RUS82614.1 - 0.0022 18.0 4.9 0.95 9.5 0.4 2.9 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 RUS82614.1 - 0.014 15.2 12.4 0.078 12.8 12.4 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CEP209_CC5 PF16574.5 RUS82614.1 - 1.1 9.5 20.9 12 6.1 1.4 4.6 1 1 2 4 4 4 0 Coiled-coil region of centrosome protein CE290 PRKG1_interact PF15898.5 RUS82614.1 - 1.7 9.6 17.7 19 6.2 5.0 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Neuralized PF07177.12 RUS82615.1 - 1.1e-33 116.3 0.0 1.3e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Neuralized TraD PF06412.11 RUS82616.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TraD CCDC24 PF15669.5 RUS82618.1 - 1.7e-44 152.1 0.7 1.7e-44 152.1 0.7 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family T6PP_N PF18572.1 RUS82618.1 - 0.032 14.1 0.5 4.5 7.2 0.0 3.1 2 1 1 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Acyltransferase PF01553.21 RUS82620.1 - 9.8e-11 41.4 0.0 3.6e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 RUS82620.1 - 1.6e-06 27.3 0.1 8.5e-06 24.9 0.1 2.0 1 1 0 1 1 1 1 Diacylglycerol acyltransferase RPAP2_Rtr1 PF04181.13 RUS82621.1 - 7.3e-21 74.3 1.5 2.1e-20 72.8 1.5 1.9 1 0 0 1 1 1 1 Rtr1/RPAP2 family Scramblase PF03803.15 RUS82621.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Scramblase PulA_N1 PF17999.1 RUS82622.1 - 0.1 13.4 0.0 14 6.5 0.0 2.3 2 0 0 2 2 2 0 Pullulanase N1-terminal domain Med16 PF11635.8 RUS82623.1 - 2.8e-65 220.7 0.1 1.2e-64 218.6 0.1 2.0 1 1 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L22 PF00237.19 RUS82624.1 - 3.9e-21 75.2 0.8 7.5e-21 74.3 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF1778 PF08681.11 RUS82625.1 - 0.094 12.7 0.3 0.4 10.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) ANAPC4_WD40 PF12894.7 RUS82626.1 - 3.1e-12 46.6 3.7 0.042 14.1 0.0 7.0 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS82626.1 - 4.5e-06 27.3 24.0 5.8 8.0 0.1 9.3 10 0 0 10 10 10 5 WD domain, G-beta repeat Drf_GBD PF06371.13 RUS82627.1 - 0.0019 17.8 0.0 0.65 9.5 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain PHC2_SAM_assoc PF16616.5 RUS82627.1 - 2.9 8.7 6.4 7.7 7.4 6.4 1.7 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Drf_FH3 PF06367.16 RUS82629.1 - 1.7e-11 44.1 0.0 2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain CTK3 PF12243.8 RUS82629.1 - 0.0014 18.6 0.1 0.0016 18.5 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Yuri_gagarin PF15934.5 RUS82629.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Yuri gagarin BAF PF02961.14 RUS82629.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Barrier to autointegration factor FH2 PF02181.23 RUS82630.1 - 1.1e-81 274.8 2.3 3.2e-81 273.3 2.3 1.8 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RUS82630.1 - 1.6e-07 31.2 0.2 5.2e-07 29.5 0.2 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain 2-Hacid_dh PF00389.30 RUS82630.1 - 0.0053 16.4 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Pkinase_Tyr PF07714.17 RUS82632.1 - 2.5e-65 220.3 0.0 2.8e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS82632.1 - 1.3e-27 96.9 0.0 1.5e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RUS82632.1 - 0.0019 17.6 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like CK2S PF15011.6 RUS82633.1 - 7.6e-14 51.9 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Casein Kinase 2 substrate DUF3740 PF12548.8 RUS82633.1 - 0.2 12.1 1.2 0.4 11.1 0.4 1.8 2 0 0 2 2 2 0 Sulfatase protein adh_short PF00106.25 RUS82634.1 - 4.7e-27 94.7 0.0 2.4e-23 82.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82634.1 - 9.2e-16 58.1 0.1 1e-14 54.6 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS82634.1 - 4.9e-08 33.1 0.2 1.4e-07 31.6 0.3 1.8 1 1 0 1 1 1 1 KR domain WW PF00397.26 RUS82634.1 - 2.2e-07 30.8 0.9 3.8e-07 30.1 0.9 1.4 1 0 0 1 1 1 1 WW domain Rsbr_N PF08678.10 RUS82634.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal Phage_Coat_Gp8 PF05371.12 RUS82634.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Phage major coat protein, Gp8 bZIP_Maf PF03131.17 RUS82635.1 - 3.6e-26 91.5 12.5 3.6e-26 91.5 12.5 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor zf-CCCH PF00642.24 RUS82635.1 - 1.7e-13 50.1 34.8 0.0091 15.9 0.2 5.9 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RUS82635.1 - 2.3e-06 28.3 33.6 0.012 16.3 5.4 6.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 RUS82635.1 - 0.00016 21.8 11.2 0.00016 21.8 11.2 3.3 1 1 2 3 3 3 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 RUS82635.1 - 0.00091 19.2 43.6 0.012 15.6 7.8 6.6 6 1 0 6 6 6 4 Zinc finger domain bZIP_2 PF07716.15 RUS82635.1 - 0.055 13.6 9.1 0.24 11.5 9.1 2.2 1 0 0 1 1 1 0 Basic region leucine zipper NLE PF08154.12 RUS82635.1 - 0.07 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 NLE (NUC135) domain zf-CCCH_4 PF18044.1 RUS82635.1 - 0.31 10.9 0.0 0.31 10.9 0.0 5.9 5 1 0 5 5 5 0 CCCH-type zinc finger bZIP_1 PF00170.21 RUS82635.1 - 3.2 7.9 16.5 1.8 8.7 12.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor Med8 PF10232.9 RUS82636.1 - 0.031 13.9 1.9 0.035 13.7 1.9 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 TSC22 PF01166.18 RUS82636.1 - 0.15 12.4 0.9 0.15 12.4 0.9 3.0 2 1 2 4 4 4 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 RUS82636.1 - 0.45 10.6 11.2 3.7 7.6 3.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 RUS82636.1 - 0.72 9.6 8.8 1.4 8.7 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1366 PF07104.11 RUS82636.1 - 1 9.1 6.3 1.3 8.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) Exonuc_VII_S PF02609.16 RUS82636.1 - 1.3 9.2 8.1 6 7.0 1.9 2.5 2 1 0 2 2 2 0 Exonuclease VII small subunit C2-C2_1 PF11618.8 RUS82637.1 - 7.7e-59 197.8 0.0 2.2e-53 180.2 0.0 2.9 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 RUS82637.1 - 2.1e-50 170.8 0.0 2.1e-50 170.8 0.0 2.9 3 0 0 3 3 3 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 RUS82637.1 - 6e-07 29.7 0.0 1.8e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain T3SS_needle_F PF09392.10 RUS82637.1 - 0.45 10.8 4.4 2.2 8.5 0.6 3.6 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF489 PF04356.12 RUS82637.1 - 2.7 8.0 13.9 3.5 7.6 6.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF1077 PF06417.12 RUS82638.1 - 1.3e-44 151.0 5.1 1.7e-44 150.6 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) NIPSNAP PF07978.13 RUS82639.1 - 4.8e-22 78.1 0.5 1.4e-18 67.0 0.3 2.5 2 1 1 3 3 3 2 NIPSNAP zf-C2H2_jaz PF12171.8 RUS82640.1 - 2.1e-08 34.3 44.9 0.0075 16.5 0.2 9.5 10 0 0 10 10 9 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS82640.1 - 9.9e-08 31.6 3.9 0.022 14.5 0.0 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 RUS82640.1 - 2.3e-07 31.0 18.8 7.7e-05 22.9 1.1 4.8 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 RUS82640.1 - 8.4e-06 26.0 60.4 0.13 12.7 0.1 10.8 10 1 1 11 11 11 6 Zinc finger, C2H2 type zf-met PF12874.7 RUS82640.1 - 1.4e-05 25.3 42.1 0.2 12.1 0.1 9.6 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS82640.1 - 4.5e-05 23.9 57.6 0.027 15.3 0.2 10.8 11 0 0 11 11 10 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RUS82640.1 - 0.0013 19.4 15.7 0.047 14.4 0.2 5.2 5 1 1 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf_C2H2_6 PF18450.1 RUS82640.1 - 0.046 13.5 0.2 0.046 13.5 0.2 4.0 4 0 0 4 4 4 0 Zinc Finger domain Mut7-C PF01927.16 RUS82640.1 - 0.17 12.0 0.7 55 3.8 0.0 3.6 3 1 0 3 3 3 0 Mut7-C RNAse domain Zn-C2H2_12 PF18112.1 RUS82640.1 - 0.86 10.1 5.2 19 5.8 0.1 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Ogr_Delta PF04606.12 RUS82640.1 - 5.3 7.1 11.3 1.1 9.3 2.4 3.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-TFIIIC PF12660.7 RUS82640.1 - 6 6.9 6.8 35 4.4 0.0 4.0 3 1 0 3 3 3 0 Putative zinc-finger of transcription factor IIIC complex Glycolytic PF00274.19 RUS82641.1 - 5.2e-82 275.4 0.0 6.8e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.19 RUS82642.1 - 5.8e-63 212.7 0.0 6.7e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Homeobox_KN PF05920.11 RUS82644.1 - 1.3e-15 57.0 0.5 2.9e-15 55.9 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS82644.1 - 6e-07 29.2 0.3 1e-06 28.5 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Arrestin_N PF00339.29 RUS82645.1 - 1.8e-37 128.7 0.0 8.3e-37 126.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS82645.1 - 1.4e-16 61.2 0.0 3.1e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 RUS82645.1 - 0.0063 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LDB19 PF13002.7 RUS82645.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Rgp1 PF08737.10 RUS82645.1 - 0.12 11.5 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Rgp1 Methyltransf_25 PF13649.6 RUS82646.1 - 1.7e-38 131.2 0.0 1.9e-17 63.8 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 RUS82646.1 - 2e-36 124.5 0.0 2.7e-17 63.2 0.0 2.9 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RUS82646.1 - 1.9e-29 102.6 0.0 2.4e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 RUS82646.1 - 8.3e-29 100.3 0.1 2.8e-13 49.9 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 RUS82646.1 - 6.1e-24 84.6 0.1 1.4e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS82646.1 - 1e-23 83.9 0.5 3.5e-11 43.7 0.0 3.4 4 0 0 4 4 3 2 Methyltransferase domain CMAS PF02353.20 RUS82646.1 - 2.1e-14 53.5 0.0 2e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 RUS82646.1 - 3.4e-13 49.6 0.0 2e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase NodS PF05401.11 RUS82646.1 - 6e-10 39.1 0.0 9.6e-09 35.1 0.0 2.4 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 RUS82646.1 - 1.1e-09 38.1 0.0 7e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 RUS82646.1 - 1.3e-09 38.1 0.0 3.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 RUS82646.1 - 1.1e-08 35.5 0.0 0.0068 16.5 0.0 3.4 2 2 1 3 3 3 2 FtsJ-like methyltransferase TehB PF03848.14 RUS82646.1 - 1.8e-08 34.1 0.0 0.0038 16.6 0.0 2.4 2 0 0 2 2 2 2 Tellurite resistance protein TehB RrnaAD PF00398.20 RUS82646.1 - 3.1e-08 33.0 0.1 2.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 RUS82646.1 - 1.1e-07 31.3 0.0 0.0036 16.6 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase domain CheR PF01739.18 RUS82646.1 - 2e-07 30.7 0.0 0.0021 17.6 0.0 2.8 2 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 RUS82646.1 - 4.1e-05 23.6 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.18 RUS82646.1 - 6.8e-05 22.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Bin3 PF06859.12 RUS82646.1 - 8.3e-05 23.2 0.4 3.2 8.4 0.0 3.9 3 0 0 3 3 3 1 Bicoid-interacting protein 3 (Bin3) Met_10 PF02475.16 RUS82646.1 - 0.00014 21.7 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_15 PF09445.10 RUS82646.1 - 0.00026 20.6 0.1 0.08 12.5 0.0 2.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 RUS82646.1 - 0.00089 18.7 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 RUS82646.1 - 0.0015 18.1 0.2 0.11 12.0 0.1 2.7 2 1 0 2 2 2 1 Histone methylation protein DOT1 PMT2_N PF17987.1 RUS82646.1 - 0.0035 17.5 0.1 0.013 15.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoethanolamine N-methyltransferase 2 N-terminal Mlp PF03304.13 RUS82646.1 - 0.0062 16.8 2.1 0.018 15.3 0.5 2.5 2 0 0 2 2 2 1 Mlp lipoprotein family MetW PF07021.12 RUS82646.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PPP4R2 PF09184.11 RUS82648.1 - 9.3e-05 22.2 4.8 9.3e-05 22.2 4.8 4.6 3 2 2 5 5 5 1 PPP4R2 RVT_1 PF00078.27 RUS82649.1 - 2.6e-34 118.7 0.0 5.3e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3807 PF12720.7 RUS82649.1 - 0.0013 19.1 16.4 0.0013 19.1 16.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 RUS82649.1 - 0.0051 16.7 15.8 0.0051 16.7 15.8 2.1 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 RUS82649.1 - 0.0062 15.6 2.7 0.01 14.8 2.7 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 RUS82649.1 - 0.018 14.5 13.1 0.034 13.6 13.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) tRNA-synt_2c PF01411.19 RUS82649.1 - 0.03 12.8 6.1 0.051 12.1 6.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) Presenilin PF01080.17 RUS82649.1 - 0.077 11.7 8.9 0.13 11.0 8.9 1.3 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 RUS82649.1 - 0.2 11.9 5.1 0.058 13.7 1.9 1.7 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 RUS82649.1 - 0.22 9.7 15.5 0.37 9.0 15.5 1.3 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 RUS82649.1 - 0.23 11.3 4.9 0.63 9.9 4.9 1.7 1 0 0 1 1 1 0 N-glycosylation protein TMEM214 PF10151.9 RUS82649.1 - 0.6 8.5 23.0 1.1 7.6 23.0 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF2052 PF09747.9 RUS82649.1 - 1.3 9.2 12.9 0.041 14.0 6.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GNAT_acetyltr_2 PF13718.6 RUS82649.1 - 1.3 8.4 7.8 2.7 7.3 7.8 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2126 PF09899.9 RUS82649.1 - 2.6 6.0 6.8 4.2 5.3 6.8 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EIIBC-GUT_N PF03612.14 RUS82649.1 - 3.6 7.3 13.0 9.6 5.9 13.0 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PcfK PF14058.6 RUS82649.1 - 4.6 7.5 31.6 0.17 12.2 24.9 2.0 2 0 0 2 2 2 0 PcfK-like protein Connexin PF00029.19 RUS82649.1 - 5.6 6.7 21.6 0.11 12.2 14.4 1.7 2 0 0 2 2 2 0 Connexin RPA43_OB PF17875.1 RUS82649.1 - 5.7 7.6 12.8 5.2 7.7 9.0 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4228 PF14009.6 RUS82649.1 - 6.1 7.2 15.2 12 6.2 15.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) CLN3 PF02487.17 RUS82649.1 - 7.8 5.4 8.7 15 4.5 8.7 1.4 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 RUS82649.1 - 9.2 6.4 19.0 0.42 10.8 12.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1556 PF07590.11 RUS82650.1 - 0.05 13.9 0.1 0.076 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) TMEM154 PF15102.6 RUS82651.1 - 0.1 12.5 0.6 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.16 RUS82651.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.14 RUS82651.1 - 0.17 12.0 1.9 0.35 11.0 1.9 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Nefa_Nip30_N PF10187.9 RUS82652.1 - 4.4e-20 72.0 15.9 4.4e-20 72.0 15.9 1.9 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DDE_Tnp_IS66 PF03050.14 RUS82652.1 - 0.38 10.2 3.8 0.55 9.6 3.8 1.3 1 0 0 1 1 1 0 Transposase IS66 family CytochromB561_N PF09786.9 RUS82653.1 - 1.5e-51 176.1 6.0 1.9e-51 175.8 6.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal ATP-grasp_2 PF08442.10 RUS82654.1 - 1e-72 243.9 1.5 2e-72 243.0 1.5 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 RUS82654.1 - 5.6e-27 94.4 0.6 1.1e-26 93.5 0.6 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 RUS82654.1 - 2.3e-07 30.5 2.0 1.3e-06 28.1 2.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 RUS82654.1 - 0.0044 16.8 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Citrate_bind PF16114.5 RUS82654.1 - 0.023 14.2 0.1 0.058 12.9 0.1 1.7 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Tmem26 PF09772.9 RUS82656.1 - 1.2e-63 215.2 14.9 2.7e-63 214.0 14.9 1.5 1 1 0 1 1 1 1 Transmembrane protein 26 ECM11 PF15463.6 RUS82657.1 - 0.0098 16.5 2.9 0.24 12.0 1.5 3.1 1 1 2 3 3 3 2 Extracellular mutant protein 11 Nop14 PF04147.12 RUS82658.1 - 7.6e-07 27.8 27.8 1e-06 27.3 27.8 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS82658.1 - 2.6e-06 27.1 28.9 4.2e-06 26.4 28.9 1.3 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 RUS82658.1 - 0.0017 18.6 44.2 0.0032 17.6 44.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Drc1-Sld2 PF11719.8 RUS82658.1 - 0.0028 17.3 27.6 0.0044 16.6 27.6 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein RR_TM4-6 PF06459.12 RUS82658.1 - 0.0031 17.4 28.2 0.0052 16.7 28.2 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.13 RUS82658.1 - 0.0041 17.0 18.0 0.0069 16.3 18.0 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region SID-1_RNA_chan PF13965.6 RUS82658.1 - 0.028 12.8 0.2 0.034 12.6 0.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4604 PF15377.6 RUS82658.1 - 0.029 14.8 44.3 0.066 13.6 44.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mpp10 PF04006.12 RUS82658.1 - 0.044 12.2 41.3 0.067 11.6 41.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CCSAP PF15748.5 RUS82658.1 - 0.083 13.0 26.8 0.16 12.1 26.8 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Merozoite_SPAM PF07133.11 RUS82658.1 - 0.085 12.9 55.5 0.15 12.1 55.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 RUS82658.1 - 0.38 10.1 50.3 0.61 9.4 50.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RUS82658.1 - 0.47 8.7 38.4 0.72 8.1 38.4 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_11 PF13086.6 RUS82658.1 - 0.6 9.8 14.3 1.1 9.0 14.3 1.3 1 0 0 1 1 1 0 AAA domain Rrn6 PF10214.9 RUS82658.1 - 1.5 7.2 8.2 2.6 6.4 8.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor eIF3_subunit PF08597.10 RUS82658.1 - 1.9 8.3 46.7 0.98 9.3 6.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3807 PF12720.7 RUS82658.1 - 2.1 8.6 34.0 4.1 7.6 34.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CCDC106 PF15794.5 RUS82658.1 - 2.4 7.8 25.8 4.9 6.8 25.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC27 PF09507.10 RUS82658.1 - 2.4 7.5 41.3 4.9 6.4 41.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PRP1_N PF06424.12 RUS82658.1 - 5.8 7.3 27.7 14 6.1 26.1 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Presenilin PF01080.17 RUS82658.1 - 8.4 5.0 25.0 15 4.2 25.0 1.3 1 0 0 1 1 1 0 Presenilin MTS PF05175.14 RUS82659.1 - 7.7e-10 38.6 0.0 5.5e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 RUS82659.1 - 1.1e-09 38.8 0.0 2.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain RrnaAD PF00398.20 RUS82659.1 - 1.4e-07 30.8 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RUS82659.1 - 4.8e-07 30.4 0.0 2.1e-06 28.4 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS82659.1 - 2.5e-06 28.1 0.0 2.3e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS82659.1 - 9.1e-06 25.4 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 RUS82659.1 - 9.7e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS82659.1 - 3.9e-05 24.2 0.0 0.00059 20.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS82659.1 - 0.00012 22.0 0.0 0.00043 20.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RUS82659.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 RUS82659.1 - 0.0026 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 RUS82659.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 RUS82659.1 - 0.022 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.20 RUS82659.1 - 0.031 13.6 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 RUS82659.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 RUS82659.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 RUS82659.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 FancD2 PF14631.6 RUS82660.1 - 0 1108.3 23.9 0 1106.9 23.9 1.5 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 RUS82660.1 - 9.9e-05 22.7 5.1 0.00012 22.4 0.3 3.0 2 0 0 2 2 2 1 FANCI solenoid 2 Paf1 PF03985.13 RUS82660.1 - 0.83 8.6 6.7 1.5 7.7 6.7 1.3 1 0 0 1 1 1 0 Paf1 Tub_N PF16322.5 RUS82660.1 - 0.86 10.0 8.2 6.3 7.2 2.6 3.0 3 0 0 3 3 3 0 Tubby N-terminal SRP_TPR_like PF17004.5 RUS82662.1 - 4.4e-24 84.8 5.3 4.2e-23 81.6 1.9 3.2 3 0 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 RUS82662.1 - 4.5e-18 65.4 4.6 4.5e-18 65.4 4.6 2.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 RUS82662.1 - 8.9e-14 51.0 8.7 0.007 17.1 0.4 9.0 4 3 6 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS82662.1 - 3.9e-10 39.8 13.4 0.009 16.2 0.8 6.2 3 2 4 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RUS82662.1 - 1e-09 38.8 20.8 0.0045 17.5 1.5 7.4 3 3 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS82662.1 - 1.3e-05 25.5 16.1 7.4 7.4 0.1 8.3 9 0 0 9 9 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RUS82662.1 - 1.8e-05 24.4 3.9 1.2 8.8 0.0 4.5 3 1 2 5 5 5 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_2 PF07719.17 RUS82662.1 - 2.3e-05 24.2 15.0 0.79 10.0 0.0 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS82662.1 - 9.3e-05 22.6 13.0 1.1 9.6 0.2 6.9 5 2 2 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 RUS82662.1 - 0.00016 22.2 2.9 0.024 15.1 0.1 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 RUS82662.1 - 0.00016 22.2 7.4 0.43 11.3 0.4 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS82662.1 - 0.00023 20.8 5.4 0.19 11.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS82662.1 - 0.00028 20.4 8.5 0.085 12.2 0.2 3.6 2 2 0 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 RUS82662.1 - 0.00058 19.9 13.1 1.1 9.7 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat ChAPs PF09295.10 RUS82662.1 - 0.0011 18.0 4.8 0.62 9.0 0.7 3.2 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 RUS82662.1 - 0.0022 17.5 6.2 0.008 15.6 2.0 3.4 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 RUS82662.1 - 0.0035 17.0 0.5 0.55 10.0 0.1 4.2 3 0 0 3 3 3 1 TPR repeat VP4_haemagglut PF00426.18 RUS82662.1 - 0.0042 17.3 0.1 0.009 16.2 0.1 1.5 1 0 0 1 1 1 1 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain TPR_9 PF13371.6 RUS82662.1 - 0.025 14.7 0.2 38 4.5 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 RUS82662.1 - 0.026 14.2 12.6 0.49 10.1 3.6 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain UVR PF02151.19 RUS82662.1 - 0.03 14.1 0.0 0.15 11.8 0.0 2.3 1 0 0 1 1 1 0 UvrB/uvrC motif Rep_Org_C PF06926.11 RUS82662.1 - 0.12 12.7 0.3 14 6.0 0.0 2.7 1 1 1 2 2 2 0 Putative replisome organiser protein C-terminus DUF4919 PF16266.5 RUS82662.1 - 0.14 12.1 3.1 3.6 7.5 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4919) PPR PF01535.20 RUS82662.1 - 0.33 11.3 1.4 30 5.1 0.2 3.9 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 RUS82662.1 - 0.65 9.9 4.1 41 4.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 RUS82662.1 - 1.9 8.8 6.3 1.9 8.8 0.0 3.5 4 1 0 4 4 4 0 Ribosomal protein L22p/L17e DUF3108 PF11306.8 RUS82663.1 - 0.54 10.2 2.8 1.2 9.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) DUF4551 PF15087.6 RUS82665.1 - 3.3e-44 151.7 0.1 3.5e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) DUF4551 PF15087.6 RUS82666.1 - 5.4e-93 312.9 0.4 7e-93 312.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) DUF3108 PF11306.8 RUS82666.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) PT PF04886.12 RUS82667.1 - 0.0052 16.3 4.3 0.0052 16.3 4.3 3.7 3 0 0 3 3 3 1 PT repeat RR_TM4-6 PF06459.12 RUS82667.1 - 0.27 11.0 12.7 0.5 10.2 12.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 RUS82667.1 - 1.1 9.4 8.3 4.4 7.5 8.3 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 RUS82667.1 - 1.6 7.6 5.6 4 6.4 5.6 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 RUS82667.1 - 8.6 5.0 13.5 20 3.8 13.5 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BIR PF00653.21 RUS82669.1 - 8.8e-20 71.1 2.0 8.8e-20 71.1 2.0 1.6 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Ig_3 PF13927.6 RUS82670.1 - 3.7e-17 62.7 4.8 4.4e-16 59.2 0.4 3.7 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RUS82670.1 - 3.2e-14 52.8 0.0 1e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS82670.1 - 3.2e-14 53.0 1.8 2e-11 44.1 0.1 3.4 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 RUS82670.1 - 2e-10 40.7 0.2 2.5e-09 37.2 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS82670.1 - 1.3e-07 31.5 3.3 0.013 15.6 0.1 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS82670.1 - 8.7e-06 25.9 0.5 0.017 15.3 0.1 4.2 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS82670.1 - 0.0021 18.4 0.0 0.065 13.6 0.0 2.8 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS82670.1 - 0.0025 18.0 0.0 0.075 13.3 0.0 2.8 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Phage_Coat_B PF05356.11 RUS82670.1 - 0.055 13.4 0.2 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Phage Coat protein B RIFIN PF02009.16 RUS82670.1 - 0.3 10.9 0.0 0.47 10.3 0.0 1.2 1 0 0 1 1 1 0 Rifin Phage_holin_3_6 PF07332.11 RUS82670.1 - 0.5 10.4 14.5 8.6 6.4 1.4 3.3 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III LRR_6 PF13516.6 RUS82671.1 - 1.6e-18 65.1 22.6 0.00088 19.1 0.2 10.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 RUS82671.1 - 3.4e-14 52.7 18.3 0.14 12.7 0.0 8.0 5 2 1 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 RUS82671.1 - 1.3e-11 44.2 1.2 3.7e-11 42.7 1.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS82671.1 - 8.7e-08 31.9 0.8 6.2e-07 29.1 0.4 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 RUS82671.1 - 0.032 14.7 23.4 20 6.2 0.0 10.3 11 2 0 11 11 11 0 Leucine Rich Repeat F-box_4 PF15966.5 RUS82671.1 - 0.16 11.8 4.6 5.3 7.0 0.0 2.9 3 0 0 3 3 3 0 F-box LRR_8 PF13855.6 RUS82671.1 - 0.35 10.7 13.6 12 5.8 1.6 6.1 4 3 2 6 6 6 0 Leucine rich repeat CLP1_P PF16575.5 RUS82672.1 - 3.7e-35 121.4 0.0 6.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 RUS82672.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF737 PF05300.11 RUS82673.1 - 1e-05 26.0 12.7 0.0013 19.1 6.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF737) DUF1690 PF07956.11 RUS82673.1 - 6.1e-05 23.5 5.5 0.00012 22.5 5.5 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) C_GCAxxG_C_C PF09719.10 RUS82673.1 - 0.0075 16.5 1.5 0.01 16.1 1.5 1.3 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) Pet191_N PF10203.9 RUS82673.1 - 0.037 14.3 2.3 0.062 13.6 2.0 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Sds3 PF08598.11 RUS82673.1 - 0.045 13.7 1.6 0.075 13.0 1.6 1.3 1 0 0 1 1 1 0 Sds3-like COX17 PF05051.13 RUS82673.1 - 0.096 13.0 1.2 0.19 12.1 1.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cofilin_ADF PF00241.20 RUS82674.1 - 6.5e-38 129.2 0.1 1e-22 80.2 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DHR-2 PF06920.13 RUS82675.1 - 9.1e-75 252.3 5.1 1.5e-73 248.2 5.1 2.6 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 RUS82675.1 - 1.1e-71 241.7 0.6 2.3e-71 240.7 0.6 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 RUS82675.1 - 4e-40 137.7 1.0 1e-39 136.3 1.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 RUS82675.1 - 0.009 16.3 0.0 0.071 13.4 0.0 2.4 2 0 0 2 2 2 1 C2 domain Virulence_RhuM PF13310.6 RUS82676.1 - 0.022 14.0 1.2 1.6 7.9 0.2 2.0 1 1 1 2 2 2 0 Virulence protein RhuM family DUF3657 PF12394.8 RUS82676.1 - 0.46 11.1 7.0 2.8 8.6 0.9 2.9 3 0 0 3 3 3 0 Protein FAM135 Gp5_C PF06715.12 RUS82676.1 - 2.7 8.3 0.1 2.7 8.3 0.1 7.3 6 2 1 7 7 7 0 Gp5 C-terminal repeat (3 copies) Peptidase_M13_N PF05649.13 RUS82677.1 - 2.4e-22 80.2 0.0 2.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 FeoB_associated PF12669.7 RUS82677.1 - 0.015 15.7 0.5 0.026 14.9 0.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TRIQK PF15168.6 RUS82677.1 - 0.42 10.6 1.4 0.67 9.9 1.4 1.2 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Peptidase_M13_N PF05649.13 RUS82678.1 - 2.7e-50 172.2 3.7 4e-50 171.6 3.7 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS82678.1 - 1.4e-10 41.1 0.0 4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M13 Glyco_hydro_1 PF00232.18 RUS82678.1 - 0.027 12.9 0.3 0.038 12.4 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 TnpW PF14202.6 RUS82678.1 - 0.16 11.8 2.1 0.36 10.7 0.6 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Peptidase_M13 PF01431.21 RUS82679.1 - 4.8e-30 104.7 0.0 5.1e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 LDB19 PF13002.7 RUS82680.1 - 0.79 9.4 12.7 1.8 8.2 0.3 4.3 1 1 2 4 4 4 0 Arrestin_N terminal like Amelogenin PF02948.15 RUS82680.1 - 4.8 7.8 10.0 8.9 6.9 1.3 2.8 1 1 1 2 2 2 0 Amelogenin RD3 PF14473.6 RUS82681.1 - 1.6e-28 99.1 0.1 9.9e-27 93.4 0.7 2.1 2 0 0 2 2 2 2 RD3 protein DRMBL PF07522.14 RUS82682.1 - 4e-08 33.4 0.0 6.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 RUS82682.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Mob1_phocein PF03637.17 RUS82683.1 - 6.1e-58 195.6 3.1 8.9e-58 195.0 3.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family LIM PF00412.22 RUS82684.1 - 6.1e-39 132.1 47.5 6.4e-14 51.9 10.0 3.1 3 0 0 3 3 3 3 LIM domain Cytochrom_C550 PF14495.6 RUS82684.1 - 0.053 13.2 0.1 0.053 13.2 0.1 3.0 3 0 0 3 3 3 0 Cytochrome c-550 domain zf_UBZ PF18439.1 RUS82684.1 - 0.12 11.9 31.8 0.16 11.6 1.5 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger DUF2616 PF11077.8 RUS82684.1 - 1.2 8.8 23.3 0.42 10.3 2.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) UPAR_LY6_2 PF16975.5 RUS82684.1 - 1.6 8.9 26.8 2.2 8.5 12.4 3.4 2 1 1 3 3 3 0 Ly6/PLAUR domain-containing protein 6, Lypd6 PAP2 PF01569.21 RUS82685.1 - 2.8e-26 91.9 1.3 2.8e-26 91.9 1.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RUS82685.1 - 0.00093 18.9 2.8 0.00093 18.9 2.8 2.4 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 RUS82685.1 - 0.013 16.0 2.1 0.013 16.0 2.1 2.5 3 1 0 3 3 3 0 PAP2 superfamily C-terminal zf-C4 PF00105.18 RUS82686.1 - 1.7e-23 82.9 12.3 1.7e-23 82.9 12.3 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Kei1 PF08552.11 RUS82686.1 - 0.03 14.2 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SDA1 PF05285.12 RUS82686.1 - 0.46 9.9 22.4 0.92 8.9 22.4 1.4 1 0 0 1 1 1 0 SDA1 Ribosomal_L32e PF01655.18 RUS82687.1 - 2.1e-52 176.1 3.9 2.5e-52 175.8 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 BORA_N PF15280.6 RUS82688.1 - 5.4e-17 62.2 3.1 6e-08 32.6 0.2 3.1 2 1 1 3 3 3 2 Protein aurora borealis N-terminus zf-TRAF PF02176.18 RUS82690.1 - 3.5e-15 56.4 33.5 1.2e-09 38.7 6.8 4.1 2 1 2 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 RUS82690.1 - 4.7e-12 45.5 5.2 4.7e-12 45.5 5.2 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82690.1 - 8.1e-09 35.2 5.3 8.1e-09 35.2 5.3 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS82690.1 - 5.5e-08 32.7 7.8 5.5e-08 32.7 7.8 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RUS82690.1 - 7.6e-08 32.6 4.9 7.6e-08 32.6 4.9 3.8 3 2 1 4 4 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 RUS82690.1 - 1.1e-07 31.9 5.0 1.1e-07 31.9 5.0 2.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RUS82690.1 - 3.2e-06 26.9 3.4 3.2e-06 26.9 3.4 3.7 3 1 1 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RUS82690.1 - 1.7e-05 24.5 2.4 1.7e-05 24.5 2.4 2.8 3 0 0 3 3 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 RUS82690.1 - 9.4e-05 22.3 3.6 9.4e-05 22.3 3.6 3.5 3 1 0 3 3 2 1 zinc-RING finger domain U-box PF04564.15 RUS82690.1 - 0.00012 22.2 1.3 0.0013 18.9 0.0 3.0 4 0 0 4 4 3 1 U-box domain zf-TRAF_2 PF15965.5 RUS82690.1 - 0.0025 18.2 30.8 0.064 13.7 14.3 3.5 1 1 3 4 4 4 2 TRAF-like zinc-finger TACC_C PF05010.14 RUS82690.1 - 0.018 14.8 0.7 0.018 14.8 0.7 1.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prok-RING_4 PF14447.6 RUS82690.1 - 0.021 14.7 5.2 0.021 14.7 5.2 3.2 2 2 1 3 3 2 0 Prokaryotic RING finger family 4 RasGAP_C PF03836.15 RUS82690.1 - 0.04 14.1 0.1 0.081 13.1 0.1 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF2383 PF09537.10 RUS82690.1 - 0.056 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DivIC PF04977.15 RUS82690.1 - 0.12 12.2 2.6 0.27 11.0 2.6 1.5 1 0 0 1 1 1 0 Septum formation initiator zf-ACC PF17848.1 RUS82690.1 - 0.18 11.9 11.3 0.54 10.4 1.5 4.3 4 0 0 4 4 3 0 Acetyl-coA carboxylase zinc finger domain Csm1_N PF18504.1 RUS82690.1 - 2 8.8 4.8 0.35 11.2 0.8 1.7 2 0 0 2 2 1 0 Csm1 N-terminal domain HIP1_clath_bdg PF16515.5 RUS82690.1 - 2.9 8.6 5.7 0.58 10.8 1.4 2.0 2 1 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 A_deamin PF02137.18 RUS82691.1 - 1.6e-57 195.5 0.0 6.1e-57 193.5 0.0 2.0 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 RUS82691.1 - 9.7e-12 45.4 0.1 2.2e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif SWIRM-assoc_3 PF16498.5 RUS82692.1 - 0.078 13.2 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal MFS_1 PF07690.16 RUS82693.1 - 4.5e-09 35.7 31.5 1.2e-06 27.7 11.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.16 RUS82693.1 - 0.00053 19.7 5.1 0.00053 19.7 5.1 3.3 3 2 0 4 4 4 1 Ion channel regulatory protein UNC-93 VWA PF00092.28 RUS82694.1 - 4.5e-08 33.5 0.0 2e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS82694.1 - 2.2e-07 31.5 0.0 2.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Cys_rich_CPCC PF14206.6 RUS82694.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC SET PF00856.28 RUS82695.1 - 7.5e-12 46.0 0.0 4.5e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 RUS82695.1 - 1.1e-07 31.4 4.3 1.7 9.0 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS82695.1 - 1.1e-06 28.2 2.1 0.17 11.8 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS82695.1 - 1.9e-06 28.1 10.7 1.7e-05 25.0 2.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-MYND PF01753.18 RUS82695.1 - 0.00075 19.5 9.5 0.00075 19.5 9.5 3.6 3 0 0 3 3 2 1 MYND finger DUF2460 PF09343.10 RUS82695.1 - 0.004 16.7 0.1 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) TPR_19 PF14559.6 RUS82695.1 - 0.0061 17.1 6.1 2.2 8.9 1.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RUS82695.1 - 0.012 15.5 1.7 1.8 8.6 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS82695.1 - 0.062 14.0 3.8 8.2 7.3 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS82695.1 - 0.07 12.5 0.3 0.21 10.9 0.0 1.9 2 1 0 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 RUS82695.1 - 0.25 12.3 4.6 13 6.9 0.0 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_L37ae PF01780.19 RUS82695.1 - 0.35 11.0 4.0 1.2 9.3 4.0 2.0 1 0 0 1 1 1 0 Ribosomal L37ae protein family TPR_21 PF09976.9 RUS82695.1 - 0.67 9.6 4.8 10 5.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain SIX1_SD PF16878.5 RUS82696.1 - 4.1e-18 65.9 5.9 2.3e-15 57.1 0.1 2.7 3 0 0 3 3 3 2 Transcriptional regulator, SIX1, N-terminal SD domain Homeobox_KN PF05920.11 RUS82696.1 - 5.9e-15 54.9 0.7 1.1e-14 54.0 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS82696.1 - 1.6e-07 31.0 2.6 3.8e-07 29.9 2.6 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 RUS82696.1 - 0.0017 17.8 0.2 0.0035 16.8 0.2 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Mic1 PF07035.12 RUS82696.1 - 0.0035 17.1 0.2 2.5 7.8 0.0 3.0 1 1 1 3 3 3 2 Colon cancer-associated protein Mic1-like Glyco_trans_A_1 PF09318.10 RUS82696.1 - 0.011 15.4 0.2 3.1 7.5 0.0 2.4 1 1 1 2 2 2 0 Glycosyl transferase 1 domain A TilS PF09179.11 RUS82696.1 - 0.059 13.9 2.3 0.17 12.4 2.3 1.8 1 0 0 1 1 1 0 TilS substrate binding domain eRF1_3 PF03465.15 RUS82696.1 - 0.079 13.4 0.2 16 6.0 0.0 2.4 2 0 0 2 2 2 0 eRF1 domain 3 DUF2524 PF10732.9 RUS82696.1 - 0.54 10.6 6.3 8.8 6.7 0.0 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2524) Pneumo_att_G PF05539.11 RUS82697.1 - 1.2 8.6 21.9 1.7 8.2 21.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Reprolysin_5 PF13688.6 RUS82698.1 - 1.7e-11 44.7 0.0 7.2e-11 42.6 0.0 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin PF01421.19 RUS82698.1 - 1.6e-09 38.0 0.0 3.8e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 RUS82698.1 - 2.5e-09 37.7 0.0 8.7e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 RUS82698.1 - 4.6e-09 36.7 6.1 9.5e-09 35.7 6.1 1.5 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin_2 PF13574.6 RUS82698.1 - 2e-07 31.1 0.1 4.7e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS82698.1 - 3.6e-06 26.8 0.7 1.9e-05 24.4 0.7 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS82698.1 - 0.0033 17.3 0.1 0.0045 16.9 0.1 1.4 1 1 0 1 1 1 1 Matrixin ADAM_CR_2 PF17771.1 RUS82700.1 - 5.4e-09 36.4 7.7 5.4e-09 36.4 7.7 2.9 2 0 0 2 2 1 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RUS82700.1 - 2.7e-08 34.4 0.0 9.4e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS82700.1 - 2.8e-08 34.1 0.8 1.4e-07 31.9 0.5 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS82700.1 - 6.1e-08 32.8 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS82700.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like RRN3 PF05327.11 RUS82700.1 - 0.0025 16.4 4.5 0.0035 16.0 4.5 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RUS82700.1 - 0.013 13.8 8.9 0.017 13.3 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family HA70_C PF17993.1 RUS82700.1 - 0.028 14.5 0.4 0.084 12.9 0.2 1.8 1 1 1 2 2 2 0 Haemagglutinin 70 C-terminal domain SDA1 PF05285.12 RUS82700.1 - 0.11 11.9 10.8 0.15 11.4 10.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS82700.1 - 0.21 9.6 24.8 0.32 9.1 24.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 RUS82700.1 - 1.2 6.9 4.2 1.5 6.5 4.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 RUS82700.1 - 3.9 5.8 12.5 5.4 5.3 12.5 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS82700.1 - 7.5 5.8 12.3 11 5.2 12.3 1.1 1 0 0 1 1 1 0 BUD22 DnaJ PF00226.31 RUS82701.1 - 6.2e-26 90.3 0.5 9.5e-26 89.7 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Chitin_synth_2 PF03142.15 RUS82702.1 - 1.1e-33 116.7 2.2 7.4e-32 110.7 0.6 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RUS82702.1 - 1.4e-12 47.9 2.6 5.8e-12 45.9 2.6 2.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RUS82702.1 - 4e-09 36.7 1.5 4.9e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RUS82702.1 - 0.00075 19.0 0.0 0.0046 16.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 RUS82702.1 - 0.00089 19.1 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 RhodobacterPufX PF11511.8 RUS82702.1 - 1.5 8.5 3.3 20 4.9 1.6 2.7 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF1980 PF09323.10 RUS82702.1 - 6.4 6.7 8.0 0.44 10.4 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Pkinase PF00069.25 RUS82703.1 - 2.8e-26 92.5 0.0 6.1e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82703.1 - 3.7e-10 39.5 0.0 7.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS82703.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS82703.1 - 0.009 16.0 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS82703.1 - 0.018 13.8 0.0 0.045 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase NPCC PF08058.11 RUS82704.1 - 9.5 6.3 14.8 5.1e+02 0.7 14.8 2.2 1 1 0 1 1 1 0 Nuclear pore complex component Nup84_Nup100 PF04121.13 RUS82705.1 - 1.9e-33 115.6 4.6 2.8e-33 115.0 4.6 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 CENP-L PF13092.6 RUS82705.1 - 0.058 13.6 0.6 0.43 10.8 0.6 2.3 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Nup84_Nup100 PF04121.13 RUS82706.1 - 5.2e-136 454.7 1.9 6e-136 454.5 1.9 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 ResIII PF04851.15 RUS82706.1 - 0.0015 18.6 0.2 0.0037 17.3 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CBFB_NFYA PF02045.15 RUS82707.1 - 1.4e-12 48.0 0.5 1.9e-12 47.6 0.5 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SMN PF06003.12 RUS82708.1 - 2.7e-52 177.6 28.7 8.5e-52 176.0 28.7 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 RUS82708.1 - 1.8e-06 28.0 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Tudor domain U3_snoRNA_assoc PF08297.11 RUS82708.1 - 0.35 11.6 7.2 0.79 10.5 1.1 2.3 2 0 0 2 2 2 0 U3 snoRNA associated Tudor-knot PF11717.8 RUS82708.1 - 0.37 10.7 1.9 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF2039 PF10217.9 RUS82709.1 - 6.2e-32 109.8 16.2 9.5e-32 109.2 16.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Phage_sheath_1 PF04984.14 RUS82709.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain zinc-ribbons_6 PF07191.12 RUS82709.1 - 0.36 10.8 9.7 0.7 9.9 9.7 1.5 1 0 0 1 1 1 0 zinc-ribbons Cript PF10235.9 RUS82709.1 - 3.7 8.2 19.3 88 3.8 19.3 2.3 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DUF2797 PF10977.8 RUS82709.1 - 4.6 7.1 12.0 2 8.2 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) Cytochrome_C7 PF14522.6 RUS82709.1 - 5.7 7.0 11.1 24 5.0 10.2 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c COesterase PF00135.28 RUS82710.1 - 3.4e-141 471.6 0.0 3.9e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS82710.1 - 7.3e-10 39.1 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Trypsin_2 PF13365.6 RUS82711.1 - 0.00023 22.1 0.0 0.00049 21.0 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain TraL PF07178.11 RUS82712.1 - 0.15 12.5 0.3 0.7 10.4 0.1 2.1 2 0 0 2 2 2 0 TraL protein UEV PF05743.13 RUS82713.1 - 5.4e-42 142.5 0.2 9.7e-42 141.7 0.2 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 RUS82713.1 - 3.2e-28 97.4 0.6 3.2e-28 97.4 0.6 2.1 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 RUS82713.1 - 2.4e-05 24.0 0.2 4.8e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FapA PF03961.13 RUS82713.1 - 0.0055 15.4 4.4 0.0082 14.8 4.4 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A AAA_13 PF13166.6 RUS82713.1 - 0.034 12.8 6.5 0.047 12.3 6.5 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 RUS82713.1 - 0.46 10.6 5.5 6.1 7.0 1.5 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.11 RUS82713.1 - 0.49 10.7 7.5 0.35 11.1 5.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 KxDL PF10241.9 RUS82713.1 - 3 8.2 8.2 0.46 10.8 2.5 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein TMPIT PF07851.13 RUS82713.1 - 4.3 6.5 4.4 8.9 5.4 4.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 RUS82713.1 - 7.3 6.7 6.7 17 5.4 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ANAPC3 PF12895.7 RUS82714.1 - 0.075 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HIT PF01230.23 RUS82715.1 - 4.4e-27 94.7 0.0 8.1e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RUS82715.1 - 1.9e-21 76.7 0.0 3.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1043 PF06295.12 RUS82716.1 - 1.1 9.3 6.8 0.37 10.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Lig_chan PF00060.26 RUS82719.1 - 1.2e-16 60.9 1.9 2e-16 60.2 1.9 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS82719.1 - 1e-07 32.2 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS82719.1 - 0.0027 17.2 0.0 0.003 17.0 0.0 1.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SPC25 PF06703.11 RUS82719.1 - 1.9 8.3 4.3 9.3 6.0 0.2 2.2 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short PF00106.25 RUS82720.1 - 3.6e-26 91.8 0.0 4.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82720.1 - 3.6e-15 56.2 0.0 5.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 7TM_GPCR_Srz PF10325.9 RUS82720.1 - 0.39 10.0 4.0 0.33 10.3 0.1 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz ANAPC4_WD40 PF12894.7 RUS82721.1 - 2e-08 34.4 1.0 6.1e-05 23.2 0.1 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RUS82721.1 - 1.2e-07 31.2 8.8 0.011 14.8 0.8 4.1 1 1 0 3 3 3 2 Coatomer WD associated region Clathrin PF00637.20 RUS82721.1 - 3.5e-06 27.0 11.3 0.14 12.0 0.1 5.6 4 1 1 5 5 5 3 Region in Clathrin and VPS TPR_2 PF07719.17 RUS82721.1 - 0.00017 21.5 32.8 0.082 13.1 3.3 10.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS82721.1 - 0.00044 20.1 23.9 12 6.2 0.7 9.8 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS82721.1 - 0.00064 20.2 22.0 0.46 11.0 0.4 7.5 6 3 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS82721.1 - 0.0016 19.1 22.4 1.3 10.1 0.0 9.2 11 1 1 12 12 8 1 Tetratricopeptide repeat GlgS PF08971.11 RUS82721.1 - 0.011 15.8 0.4 1.6 8.8 0.0 3.3 3 0 0 3 3 3 0 Glycogen synthesis protein TPR_1 PF00515.28 RUS82721.1 - 0.069 13.0 26.8 0.9 9.5 3.5 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS82721.1 - 0.51 10.6 20.1 4.1 7.7 1.6 7.4 6 4 2 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RUS82721.1 - 1.1 9.7 13.7 30 5.2 0.0 7.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 RUS82721.1 - 1.5 9.2 10.5 1e+02 3.5 0.1 7.2 7 1 1 8 8 7 0 PPR repeat TPR_12 PF13424.6 RUS82721.1 - 2.1 8.7 31.1 0.76 10.1 0.5 9.0 7 2 2 9 9 9 0 Tetratricopeptide repeat Vps39_1 PF10366.9 RUS82721.1 - 3.7 7.9 5.3 12 6.2 0.2 3.8 2 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 RR_TM4-6 PF06459.12 RUS82722.1 - 0.028 14.3 20.2 0.047 13.5 20.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 RUS82722.1 - 0.14 10.5 1.0 0.16 10.3 1.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3807 PF12720.7 RUS82722.1 - 0.31 11.3 23.4 0.56 10.5 23.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SprA-related PF12118.8 RUS82722.1 - 0.52 9.4 14.9 0.77 8.8 14.9 1.1 1 0 0 1 1 1 0 SprA-related family FAM60A PF15396.6 RUS82722.1 - 0.7 9.9 21.0 0.97 9.4 21.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CPSF100_C PF13299.6 RUS82722.1 - 1.5 8.9 14.5 4 7.6 14.5 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SR-25 PF10500.9 RUS82722.1 - 2.6 7.6 45.6 1.6 8.3 42.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.6 RUS82722.1 - 2.7 7.7 16.5 3.5 7.3 16.5 1.1 1 0 0 1 1 1 0 AAA domain API5 PF05918.11 RUS82722.1 - 8.5 5.1 26.4 12 4.6 26.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TMC PF07810.13 RUS82725.1 - 1.6e-35 122.0 1.1 5.8e-35 120.2 1.1 2.0 1 0 0 1 1 1 1 TMC domain Chromate_transp PF02417.15 RUS82725.1 - 0.86 9.7 14.7 0.18 11.9 0.7 3.0 2 1 0 3 3 3 0 Chromate transporter Clat_adaptor_s PF01217.20 RUS82726.1 - 1.9e-34 118.6 1.1 2.4e-34 118.3 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5444 PF17519.2 RUS82726.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5444) EMP70 PF02990.16 RUS82727.1 - 5.5e-159 530.2 21.7 7.4e-159 529.7 21.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 EVC2_like PF12297.8 RUS82727.1 - 0.21 10.2 2.0 20 3.7 0.0 2.1 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DUF4446 PF14584.6 RUS82727.1 - 0.29 11.1 1.0 9.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CUB PF00431.20 RUS82728.1 - 1.4e-145 476.0 5.6 3e-33 114.4 0.0 5.5 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 RUS82728.1 - 1.2e-70 237.1 0.0 2e-70 236.3 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 RUS82728.1 - 1.3e-14 54.2 39.8 7.2e-10 39.0 11.6 3.4 3 0 0 3 3 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 RUS82728.1 - 7.7e-13 48.4 26.1 2.5e-06 27.6 8.3 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 RUS82728.1 - 2.2e-11 43.5 9.8 2.2e-05 24.3 0.8 3.4 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 RUS82728.1 - 3.9e-06 27.0 23.2 0.0018 18.5 4.6 3.8 2 1 1 3 3 3 2 EGF-like domain Reprolysin_4 PF13583.6 RUS82728.1 - 0.013 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RUS82728.1 - 0.053 13.4 0.6 0.28 11.0 0.1 2.2 2 1 1 3 3 3 0 Matrixin hEGF PF12661.7 RUS82728.1 - 0.077 13.7 17.9 0.63 10.8 3.9 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 RUS82728.1 - 0.49 10.7 18.2 1.1 9.6 5.6 3.1 2 0 0 2 2 2 0 Pvs28 EGF domain GREB1 PF15782.5 RUS82728.1 - 9.5 3.2 11.1 13 2.7 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gelsolin PF00626.22 RUS82729.1 - 6.4e-72 237.5 0.2 9.2e-17 60.7 0.0 6.3 6 0 0 6 6 6 5 Gelsolin repeat VHP PF02209.19 RUS82729.1 - 3.7e-13 49.3 8.3 1.2e-12 47.7 8.3 2.0 1 0 0 1 1 1 1 Villin headpiece domain PMP22_Claudin PF00822.20 RUS82730.1 - 6.5e-20 71.7 4.3 2.4e-19 69.8 4.3 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS82730.1 - 5.2e-18 65.5 0.7 5.2e-16 59.0 0.7 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS82730.1 - 0.0079 16.1 1.6 0.0079 16.1 1.6 1.8 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF716 PF04819.12 RUS82730.1 - 0.0092 15.6 0.8 0.047 13.3 0.4 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF716) OAD_gamma PF04277.13 RUS82730.1 - 0.018 15.6 2.1 0.6 10.7 0.1 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain NicO PF03824.16 RUS82730.1 - 0.17 11.2 4.8 0.35 10.2 4.8 1.5 1 1 0 1 1 1 0 High-affinity nickel-transport protein Lectin_C PF00059.21 RUS82731.1 - 1.4e-24 86.8 10.3 2.7e-15 57.0 1.0 3.2 2 1 0 2 2 2 2 Lectin C-type domain Fibrillarin PF01269.17 RUS82732.1 - 1.2e-38 132.5 0.0 1.4e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin KcnmB2_inactiv PF09303.10 RUS82733.1 - 0.057 13.2 0.0 0.26 11.1 0.0 2.2 1 0 0 1 1 1 0 KCNMB2, ball and chain domain SNF2_N PF00176.23 RUS82734.1 - 1.3e-76 257.6 0.1 2.2e-76 256.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 RUS82734.1 - 1.8e-17 63.1 0.0 4.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.6 RUS82734.1 - 8.3e-09 35.2 7.2 1.7e-08 34.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS82734.1 - 4.1e-08 32.9 7.1 8.1e-08 32.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS82734.1 - 5.5e-08 32.6 7.9 1e-07 31.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS82734.1 - 6.9e-07 29.5 7.8 6.9e-07 29.5 7.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RUS82734.1 - 3.6e-06 26.8 6.4 8.6e-06 25.6 6.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS82734.1 - 6.9e-06 25.8 7.1 1.5e-05 24.8 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS82734.1 - 5.4e-05 23.1 4.7 0.00012 22.0 4.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS82734.1 - 0.0033 17.5 8.3 0.0062 16.7 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RUS82734.1 - 0.0073 16.3 0.6 0.018 15.1 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RUS82734.1 - 0.0096 15.6 3.1 0.024 14.4 3.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 RUS82734.1 - 0.031 14.6 5.7 0.1 12.9 5.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 RUS82734.1 - 0.085 12.7 1.0 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Nse PF11789.8 RUS82734.1 - 0.17 11.7 2.8 0.4 10.5 2.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RUS82734.1 - 0.82 9.5 5.6 1.9 8.4 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3524 PF12038.8 RUS82735.1 - 2.9e-67 225.7 0.0 5.6e-67 224.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 RUS82735.1 - 3.5e-09 36.4 0.0 6.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Met_asp_mut_E PF06368.11 RUS82735.1 - 0.21 10.1 0.0 13 4.1 0.0 2.1 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) Polyketide_cyc PF03364.20 RUS82737.1 - 5.9e-07 29.7 0.0 7.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Erf4 PF10256.9 RUS82737.1 - 0.031 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DDE_Tnp_IS1595 PF12762.7 RUS82738.1 - 5.1e-19 68.8 0.0 1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 ISXO2-like transposase domain KH_1 PF00013.29 RUS82739.1 - 0.012 15.4 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 KH domain Ras PF00071.22 RUS82740.1 - 3.7e-34 117.7 0.0 4.6e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS82740.1 - 7.7e-16 58.4 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS82740.1 - 2.1e-07 30.6 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS82740.1 - 0.012 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Keratin_B2_2 PF13885.6 RUS82741.1 - 0.00076 19.4 105.6 1.8e+04 -69.7 105.6 6.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein PUF PF00806.19 RUS82741.1 - 0.14 11.9 0.0 5.1e+02 0.7 0.0 5.8 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Ras PF00071.22 RUS82742.1 - 3e-32 111.5 0.0 3.7e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS82742.1 - 3.1e-17 62.9 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS82742.1 - 0.00074 19.0 0.0 0.001 18.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 RUS82742.1 - 0.00093 19.6 0.0 0.0017 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 RUS82742.1 - 0.0035 16.6 0.0 0.0083 15.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain GTP_EFTU PF00009.27 RUS82742.1 - 0.0056 16.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 RUS82742.1 - 0.012 15.1 0.1 0.027 14.0 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 RUS82742.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RUS82742.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 RUS82742.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RUS82742.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 RUS82742.1 - 0.036 14.0 0.0 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 RUS82742.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 RUS82742.1 - 0.061 13.1 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 RUS82742.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 RUS82742.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.11 RUS82742.1 - 4.1 5.6 4.7 4.6 5.4 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Guanylate_kin PF00625.21 RUS82744.1 - 2.1e-57 193.7 0.0 2.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 RUS82745.1 - 2.5e-17 63.0 0.3 4.7e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 RUS82745.1 - 4.2e-10 39.2 0.7 9.8e-10 38.0 0.3 1.8 2 0 0 2 2 2 1 L27 domain Herpes_LMP1 PF05297.11 RUS82745.1 - 0.00045 19.5 1.0 0.00054 19.3 1.0 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) PDZ_6 PF17820.1 RUS82745.1 - 0.0016 18.2 0.2 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS82745.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 PDZ domain WD40 PF00400.32 RUS82746.1 - 2.2e-05 25.1 6.6 0.17 12.8 1.5 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HPS3_N PF14761.6 RUS82746.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Pkinase PF00069.25 RUS82751.1 - 6.3e-60 202.8 0.0 7.5e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82751.1 - 1.4e-24 86.8 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS82751.1 - 6.3e-05 22.4 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS82751.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS82751.1 - 0.05 13.2 0.0 6 6.4 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Gly_transf_sug PF04488.15 RUS82752.1 - 2.4e-17 63.3 0.8 4.3e-17 62.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 RUS82752.1 - 2.8e-05 23.6 2.8 0.028 13.7 0.0 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DUF3987 PF13148.6 RUS82753.1 - 1e-23 84.0 0.0 6.8e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Focadhesin PF11229.8 RUS82755.1 - 4.3e-77 259.7 8.3 1.5e-52 178.6 1.4 2.1 2 0 0 2 2 2 2 Focadhesin DUF3730 PF12530.8 RUS82756.1 - 6.5e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 RUS82756.1 - 0.0035 17.7 1.0 0.022 15.2 1.2 2.1 2 0 0 2 2 2 1 HEAT repeats Misat_Tub_SegII PF10644.9 RUS82756.1 - 0.022 15.1 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain HEAT PF02985.22 RUS82756.1 - 0.06 13.6 0.1 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat DDHD PF02862.17 RUS82757.1 - 0.00024 21.3 2.0 0.00025 21.3 2.0 1.2 1 0 0 1 1 1 1 DDHD domain Zip PF02535.22 RUS82757.1 - 0.00038 19.8 1.8 0.00039 19.7 1.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 RUS82757.1 - 0.0011 19.4 15.1 0.0016 18.8 15.1 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 Ndc1_Nup PF09531.10 RUS82757.1 - 0.0017 17.1 3.0 0.0018 17.1 3.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF262 PF03235.14 RUS82757.1 - 0.012 15.8 4.2 0.014 15.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF5308 PF17233.2 RUS82757.1 - 0.019 15.2 0.5 0.023 14.9 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) OATP PF03137.20 RUS82757.1 - 0.021 13.1 4.8 0.027 12.8 4.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Otopetrin PF03189.13 RUS82757.1 - 0.037 12.8 0.3 0.04 12.7 0.3 1.3 1 0 0 1 1 1 0 Otopetrin RPOL_N PF14700.6 RUS82757.1 - 0.046 13.1 16.7 0.06 12.7 16.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF4776 PF16003.5 RUS82757.1 - 0.048 12.7 25.3 0.058 12.4 25.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) AAA_11 PF13086.6 RUS82757.1 - 0.049 13.4 17.5 0.069 12.9 17.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3807 PF12720.7 RUS82757.1 - 0.12 12.6 28.8 0.22 11.8 28.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SLC12 PF03522.15 RUS82757.1 - 0.12 11.3 18.8 0.16 11.0 18.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 RUS82757.1 - 0.15 10.8 14.1 0.19 10.4 14.1 1.2 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 RUS82757.1 - 0.17 10.8 26.3 0.25 10.3 26.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2828 PF11443.8 RUS82757.1 - 0.24 9.4 21.9 0.31 9.1 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 RUS82757.1 - 0.27 10.6 10.6 0.35 10.3 10.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EOS1 PF12326.8 RUS82757.1 - 0.41 10.5 9.3 0.85 9.5 9.3 1.6 1 0 0 1 1 1 0 N-glycosylation protein DUF4228 PF14009.6 RUS82757.1 - 0.48 10.8 14.7 0.74 10.2 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DAG_kinase_N PF14513.6 RUS82757.1 - 0.7 10.1 17.6 1 9.5 17.6 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CENP-N PF05238.13 RUS82757.1 - 0.7 9.1 18.8 1 8.6 18.8 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Neur_chan_memb PF02932.16 RUS82757.1 - 0.89 9.6 10.4 1.2 9.2 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 RUS82757.1 - 1.1 8.9 15.6 1.6 8.4 15.6 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like YL1 PF05764.13 RUS82757.1 - 1.5 8.9 39.6 2.1 8.4 39.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein XRN_M PF17846.1 RUS82757.1 - 1.6 7.6 14.4 2.2 7.1 14.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain LicD PF04991.13 RUS82757.1 - 1.8 8.6 21.8 2.4 8.2 21.8 1.1 1 0 0 1 1 1 0 LicD family RR_TM4-6 PF06459.12 RUS82757.1 - 1.9 8.2 33.6 2.7 7.8 33.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AF-4 PF05110.13 RUS82757.1 - 2.2 6.3 33.1 2.5 6.1 33.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4746 PF15928.5 RUS82757.1 - 2.3 7.6 20.0 3.5 7.0 20.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SRP-alpha_N PF04086.13 RUS82757.1 - 2.6 7.9 34.9 3.6 7.4 34.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2052 PF09747.9 RUS82757.1 - 2.6 8.1 20.1 3.7 7.6 20.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 RUS82757.1 - 3 8.1 15.3 4.6 7.5 15.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated AAA_23 PF13476.6 RUS82757.1 - 3.5 8.1 31.2 5.1 7.5 31.2 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 RUS82757.1 - 3.7 5.7 26.2 4.9 5.3 26.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 RUS82757.1 - 4.5 5.6 6.1 5.8 5.2 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SOBP PF15279.6 RUS82757.1 - 5.3 7.6 16.3 7.2 7.1 16.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.15 RUS82757.1 - 6.3 5.5 14.3 8.3 5.1 14.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Serinc PF03348.15 RUS82757.1 - 7.4 5.4 10.3 1.2 8.0 6.7 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) Hid1 PF12722.7 RUS82757.1 - 7.4 4.6 14.3 9.6 4.2 14.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM10 PF12519.8 RUS82757.1 - 7.6 5.3 17.3 9.6 4.9 17.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 7tm_1 PF00001.21 RUS82758.1 - 4e-22 78.8 24.6 5e-22 78.5 24.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82758.1 - 1.5e-19 70.5 21.9 2.1e-19 70.0 21.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw MFS_1 PF07690.16 RUS82759.1 - 7.3e-22 77.8 22.2 1.9e-13 50.1 3.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily APCDDC PF14921.6 RUS82760.1 - 3.6e-62 209.9 7.8 6.3e-40 137.1 4.1 2.7 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 BORA_N PF15280.6 RUS82760.1 - 0.093 12.4 2.0 0.16 11.6 2.0 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus TGF_beta PF00019.20 RUS82761.1 - 4.9e-13 49.9 0.5 8e-13 49.3 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGF_beta PF00019.20 RUS82762.1 - 4.4e-16 59.7 2.2 9.7e-16 58.6 2.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS82762.1 - 1e-08 35.2 0.1 2.4e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 TGF-beta propeptide DUF35_N PF12172.8 RUS82762.1 - 0.2 11.6 2.7 0.82 9.6 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ECH_1 PF00378.20 RUS82763.1 - 1.1e-35 123.1 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS82763.1 - 1.6e-20 73.9 0.1 2e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lactamase_B PF00753.27 RUS82764.1 - 2.9e-14 53.5 0.7 8.8e-13 48.7 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS82764.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CBFD_NFYB_HMF PF00808.23 RUS82765.1 - 1.1e-15 57.6 0.4 1.5e-15 57.2 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS82765.1 - 2.4e-09 37.6 0.4 2.9e-09 37.4 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 WD40 PF00400.32 RUS82766.1 - 5e-14 52.5 3.8 0.00014 22.6 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS82766.1 - 0.013 15.8 0.1 0.052 13.8 0.1 1.9 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FXR_C3 PF16097.5 RUS82767.1 - 0.024 15.3 1.2 0.16 12.7 0.2 2.0 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Kazal_2 PF07648.15 RUS82768.1 - 7.9e-06 25.9 43.0 0.00044 20.3 7.1 6.1 4 1 1 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS82768.1 - 1.2e-05 25.2 6.0 1.2e-05 25.2 6.0 5.5 5 1 1 6 6 6 3 Kazal-type serine protease inhibitor domain Transposase_1 PF01359.18 RUS82770.1 - 6.8e-20 70.7 0.1 1.5e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS82770.1 - 0.0006 19.6 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4 PF04545.16 RUS82770.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 RUS82770.1 - 0.075 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 RUS82770.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ank_2 PF12796.7 RUS82771.1 - 1.8e-112 368.2 16.2 6.1e-17 62.0 0.5 8.8 2 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS82771.1 - 3.8e-67 221.8 15.4 7e-10 39.3 0.0 10.0 7 3 5 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 RUS82771.1 - 3.4e-66 217.0 15.4 4.3e-05 23.8 0.1 15.6 15 1 1 16 16 16 13 Ankyrin repeat Ank_3 PF13606.6 RUS82771.1 - 1.3e-65 209.5 13.1 8.2e-05 22.7 0.0 15.5 16 0 0 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 RUS82771.1 - 4e-58 192.7 14.7 1.7e-13 50.5 0.1 11.8 4 3 8 12 12 12 12 Ankyrin repeats (many copies) DUF1843 PF08898.10 RUS82771.1 - 0.02 15.4 3.4 12 6.5 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) VWA_3_C PF18571.1 RUS82771.1 - 1 9.3 3.2 18 5.3 0.1 3.4 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain NTP_transferase PF00483.23 RUS82772.1 - 6.4e-33 114.4 0.0 8.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RUS82772.1 - 7.9e-09 34.9 9.6 3e-08 33.1 0.5 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RUS82772.1 - 2.5e-05 24.7 0.0 4.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RUS82772.1 - 0.1 12.4 0.9 0.41 10.4 0.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 RUS82772.1 - 0.19 9.8 0.1 0.27 9.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Laminin_G_2 PF02210.24 RUS82773.1 - 1.2e-55 187.4 1.0 2.8e-20 73.2 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 RUS82773.1 - 2.2e-44 150.8 0.0 2.6e-16 60.0 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain WD40 PF00400.32 RUS82773.1 - 1.2e-14 54.4 3.3 2.9e-07 31.1 0.4 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 RUS82773.1 - 6.2e-06 25.1 0.1 0.005 15.6 0.0 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RUS82773.1 - 6.4e-06 26.4 0.1 0.0027 18.0 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS82773.1 - 0.0002 20.8 0.0 0.00053 19.4 0.0 1.7 1 0 0 1 1 1 1 WD40-like domain EGF PF00008.27 RUS82773.1 - 0.0013 19.0 23.0 0.064 13.6 7.9 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS82773.1 - 1.4 9.7 17.6 2.4 8.9 4.8 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF m_DGTX_Dc1a_b_c PF17491.2 RUS82773.1 - 1.5 9.5 7.6 3.3 8.4 7.6 1.5 1 0 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Laminin_G_2 PF02210.24 RUS82774.1 - 5.8e-39 133.5 1.3 3e-22 79.5 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 RUS82774.1 - 6.7e-31 107.2 0.0 2.5e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 RUS82774.1 - 4.4e-05 23.7 2.3 0.055 13.6 0.1 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_3 PF13385.6 RUS82775.1 - 1.8e-57 193.7 8.9 6.3e-15 55.6 0.3 6.3 6 0 0 6 6 6 6 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 RUS82775.1 - 1.7e-13 51.3 2.3 0.28 11.8 0.0 6.3 6 0 0 6 6 6 5 Laminin G domain Glyco_hydro_16 PF00722.21 RUS82775.1 - 0.00054 19.5 0.0 1.1 8.7 0.0 2.8 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 CENP-B_dimeris PF09026.10 RUS82775.1 - 0.15 12.4 0.5 0.32 11.4 0.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Laminin_G_2 PF02210.24 RUS82776.1 - 1.5e-23 83.8 0.1 1.9e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS82776.1 - 6.7e-22 78.1 0.0 8.4e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain DUF4670 PF15709.5 RUS82777.1 - 5.3e-13 49.1 128.3 5.3e-13 49.1 128.3 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4670) Nop53 PF07767.11 RUS82778.1 - 0.021 14.2 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ASH PF15780.5 RUS82779.1 - 1.9e-27 95.3 20.6 5.1e-05 23.4 0.1 12.5 14 1 0 14 14 14 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RUS82779.1 - 1e-09 38.2 0.8 0.35 10.7 0.0 8.1 9 0 0 9 9 9 2 MSP (Major sperm protein) domain PapD-like PF14874.6 RUS82779.1 - 5.1e-09 36.2 0.1 0.11 12.7 0.0 5.3 5 0 0 5 5 5 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 RUS82779.1 - 1.3e-08 35.0 2.9 0.85 9.9 0.0 7.2 7 0 0 7 7 7 2 Transmembrane protein 131-like MYCBPAP PF14646.6 RUS82779.1 - 3.9e-05 22.8 0.0 2.1 7.2 0.0 4.3 4 0 0 4 4 4 2 MYCBP-associated protein family DUF1573 PF07610.11 RUS82779.1 - 0.00015 21.7 0.1 42 4.2 0.0 6.4 7 1 0 7 7 7 0 Protein of unknown function (DUF1573) Pox_RNA_pol PF03293.14 RUS82779.1 - 0.016 14.9 0.1 0.096 12.4 0.0 2.3 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Dmrt1 PF12374.8 RUS82779.1 - 0.11 12.9 0.1 2.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 MYCBPAP PF14646.6 RUS82780.1 - 7.1e-37 127.4 0.0 4.6e-36 124.7 0.0 2.1 2 0 0 2 2 2 1 MYCBP-associated protein family RP-C_C PF11800.8 RUS82780.1 - 0.16 12.0 2.5 0.45 10.6 2.5 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region Serine_rich PF08824.10 RUS82780.1 - 0.76 9.8 3.4 1.8 8.5 0.5 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain V_ATPase_I PF01496.19 RUS82780.1 - 3.8 5.3 4.7 1.3 6.9 1.1 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Caleosin PF05042.13 RUS82781.1 - 0.053 13.5 0.1 9.9 6.1 0.0 2.1 1 1 1 2 2 2 0 Caleosin related protein DUF2535 PF10751.9 RUS82781.1 - 0.07 13.7 1.3 13 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) DUF2963 PF11178.8 RUS82781.1 - 5 6.9 7.0 11 5.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Lig_chan PF00060.26 RUS82782.1 - 2e-37 128.3 0.2 3.1e-37 127.7 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS82782.1 - 4.6e-30 104.2 0.3 1.8e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS82782.1 - 1.5e-16 60.5 0.0 6.2e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 RUS82782.1 - 0.013 15.4 2.1 0.013 15.4 2.1 2.2 2 0 0 2 2 2 0 Ion channel Ala_racemase_N PF01168.20 RUS82783.1 - 1.1e-20 74.3 0.0 2.4e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Erf4 PF10256.9 RUS82784.1 - 6.3e-32 110.1 0.0 7.2e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RE_LlaJI PF09563.10 RUS82784.1 - 0.035 13.3 0.1 2.8 7.0 0.0 2.0 2 0 0 2 2 2 0 LlaJI restriction endonuclease SPC25 PF06703.11 RUS82784.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CoA_binding PF02629.19 RUS82785.1 - 6.2e-30 103.7 1.0 6.2e-30 103.7 1.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 RUS82785.1 - 4.1e-23 81.9 0.1 1.4e-22 80.2 0.1 1.8 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 RUS82785.1 - 3e-09 36.8 0.0 5.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 RUS82785.1 - 2.1e-05 25.0 0.1 4.9e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain LIM PF00412.22 RUS82787.1 - 5.8e-25 87.3 18.1 5.7e-13 48.9 8.6 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS82787.1 - 7.1e-16 57.8 0.3 1.2e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS82787.1 - 7.9e-05 22.5 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Macoilin PF09726.9 RUS82787.1 - 2.4 6.6 10.0 3.2 6.2 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 RUS82788.1 - 0.0079 14.5 21.9 0.0089 14.3 21.9 1.1 1 0 0 1 1 1 1 Nop14-like family Vfa1 PF08432.10 RUS82788.1 - 0.025 14.9 0.4 0.033 14.5 0.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 RUS82788.1 - 0.11 12.0 23.6 0.12 11.7 23.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS82788.1 - 0.26 9.3 42.5 0.32 9.0 42.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RUS82788.1 - 0.7 9.2 19.6 0.79 9.0 19.6 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 RUS82788.1 - 1.4 7.3 18.6 1.6 7.0 18.6 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RUS82788.1 - 4.1 5.6 22.1 5.2 5.2 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RUS82788.1 - 4.2 6.1 4.3 4.4 6.0 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SCAPER_N PF16501.5 RUS82789.1 - 6.3e-41 138.4 1.0 2.6e-40 136.4 0.2 2.5 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 RUS82789.1 - 3.1e-05 24.2 0.1 8.2e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS82789.1 - 0.01 16.1 0.0 0.036 14.4 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.32 RUS82791.1 - 1.5e-31 107.9 5.2 6.9e-05 23.6 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS82791.1 - 6.5e-11 42.4 0.0 0.15 12.4 0.0 5.9 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 RUS82791.1 - 0.0064 15.0 0.1 0.091 11.2 0.0 2.3 2 0 0 2 2 2 1 RAVE protein 1 C terminal IKI3 PF04762.12 RUS82791.1 - 0.079 10.9 0.1 0.6 8.0 0.0 2.2 2 1 0 2 2 2 0 IKI3 family TrmO PF01980.16 RUS82793.1 - 2.6e-43 147.0 0.0 1e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 tRNA-methyltransferase O TrmO_C PF18389.1 RUS82793.1 - 7.7e-06 25.9 1.0 7.6e-05 22.7 1.0 2.2 1 1 0 1 1 1 1 TrmO C-terminal domain GED PF02212.18 RUS82793.1 - 0.092 12.9 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain Galactosyl_T PF01762.21 RUS82794.1 - 2.4e-36 125.4 0.0 3.1e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase tRNA_m1G_MT PF01746.21 RUS82794.1 - 0.0069 16.1 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Fringe PF02434.16 RUS82794.1 - 0.022 14.2 0.4 0.074 12.5 0.4 2.0 1 1 0 1 1 1 0 Fringe-like Thioredox_DsbH PF03190.15 RUS82796.1 - 1e-74 249.9 0.0 2e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 RUS82796.1 - 5.1e-12 45.8 0.0 1.3e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 RUS82796.1 - 0.0084 15.2 0.1 3.8 6.5 0.1 3.1 3 0 0 3 3 3 1 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.6 RUS82796.1 - 0.019 15.4 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain C5-epim_C PF06662.13 RUS82796.1 - 0.046 13.2 0.4 0.24 10.9 0.1 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus LYTB PF02401.18 RUS82796.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 LytB protein Ogr_Delta PF04606.12 RUS82796.1 - 0.27 11.2 1.3 24 5.0 0.0 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Innexin PF00876.18 RUS82799.1 - 5.7e-116 387.6 18.3 6.5e-116 387.5 18.3 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 RUS82799.1 - 0.2 11.1 0.9 0.47 9.9 0.4 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B Innexin PF00876.18 RUS82800.1 - 4.3e-14 52.6 0.3 4.3e-14 52.6 0.3 1.0 1 0 0 1 1 1 1 Innexin SUR7 PF06687.12 RUS82800.1 - 0.045 13.4 1.4 0.053 13.2 1.4 1.1 1 0 0 1 1 1 0 SUR7/PalI family NIR_SIR_ferr PF03460.17 RUS82801.1 - 0.012 15.5 1.0 85 3.1 0.0 4.0 4 0 0 4 4 4 0 Nitrite/Sulfite reductase ferredoxin-like half domain GCD14_N PF14801.6 RUS82801.1 - 1.1 9.1 14.2 23 4.9 0.4 4.3 4 0 0 4 4 4 0 tRNA methyltransferase complex GCD14 subunit N-term Pinin_SDK_N PF04697.13 RUS82801.1 - 2.5 8.7 51.2 11 6.7 9.6 4.5 1 1 3 4 4 4 0 pinin/SDK conserved region VIT PF08487.10 RUS82801.1 - 2.9 8.1 5.1 73 3.6 0.0 3.8 4 0 0 4 4 4 0 Vault protein inter-alpha-trypsin domain DnaJ_C PF01556.18 RUS82802.1 - 5e-35 120.8 0.0 7.1e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS82802.1 - 1.2e-27 95.8 1.6 3.1e-27 94.5 1.5 1.7 2 0 0 2 2 2 1 DnaJ domain EGF_CA PF07645.15 RUS82804.1 - 4.1e-149 484.6 245.6 1.2e-09 38.2 6.8 18.1 18 0 0 18 18 18 17 Calcium-binding EGF domain cEGF PF12662.7 RUS82804.1 - 2.8e-116 378.8 143.6 5.6e-08 32.6 1.4 18.7 18 0 0 18 18 18 18 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS82804.1 - 2.2e-76 251.8 266.3 3.3e-05 24.1 9.0 18.4 18 0 0 18 18 18 17 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RUS82804.1 - 1.1e-58 194.0 179.9 0.00035 21.1 1.9 20.5 19 0 0 19 19 19 16 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 RUS82804.1 - 6.4e-46 154.4 180.8 0.0024 18.1 1.2 18.5 18 0 0 18 18 18 17 Pvs28 EGF domain EGF_3 PF12947.7 RUS82804.1 - 1.4e-32 111.6 239.6 0.025 14.7 5.7 20.3 18 6 0 18 18 18 17 EGF domain EGF PF00008.27 RUS82804.1 - 2.5e-24 85.2 291.0 0.055 13.8 8.9 19.0 18 0 0 18 18 18 17 EGF-like domain Nmad2 PF18753.1 RUS82804.1 - 2.4e-07 30.4 4.8 45 3.4 0.0 10.7 13 0 0 13 13 13 0 Nucleotide modification associated domain 2 VWA PF00092.28 RUS82805.1 - 1.4e-52 178.5 1.1 1.8e-35 122.7 0.3 2.0 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS82805.1 - 3.2e-13 50.2 0.1 1.5e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS82805.1 - 1.2e-10 41.6 0.1 6.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Copine PF07002.16 RUS82805.1 - 1.2e-05 24.9 0.9 0.21 11.0 0.1 3.0 3 0 0 3 3 3 2 Copine VWA_CoxE PF05762.14 RUS82805.1 - 9e-05 22.0 0.1 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein SIS PF01380.22 RUS82805.1 - 0.00039 20.3 0.2 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 SIS domain S6PP PF05116.13 RUS82805.1 - 0.0037 16.8 0.0 0.49 9.9 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Nop14 PF04147.12 RUS82806.1 - 0.0027 16.0 25.4 0.0032 15.8 25.4 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS82806.1 - 0.018 13.3 19.4 0.024 13.0 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RUS82806.1 - 0.069 11.9 2.1 0.078 11.7 2.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 RUS82806.1 - 0.22 9.6 47.9 0.28 9.2 47.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 RUS82806.1 - 0.4 10.1 30.5 0.48 9.8 30.5 1.0 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS82806.1 - 4 6.7 24.2 5.2 6.4 24.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IFT57 PF10498.9 RUS82806.1 - 7 5.5 10.5 9.2 5.1 10.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 fn3 PF00041.21 RUS82808.1 - 2.6e-06 27.7 0.2 3.3e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Fibronectin type III domain I-set PF07679.16 RUS82809.1 - 1.3e-27 95.7 0.1 3.2e-15 56.0 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS82809.1 - 7.4e-27 93.8 0.3 7e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS82809.1 - 9.5e-23 80.3 0.1 5.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS82809.1 - 1.8e-16 60.1 0.3 4.8e-07 29.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS82809.1 - 2.5e-09 37.3 0.1 0.028 14.6 0.0 3.2 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS82809.1 - 7.1e-07 29.4 0.2 0.0048 17.1 0.0 2.4 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS82809.1 - 6.1e-06 26.5 0.0 0.0013 19.1 0.0 2.3 1 1 1 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS82809.1 - 8.2e-06 25.3 0.0 0.057 13.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS82809.1 - 4.8e-05 23.3 1.2 0.17 12.0 0.0 2.6 2 2 0 2 2 2 2 C17orf99 Ig domain C2-set PF05790.15 RUS82809.1 - 0.034 14.3 0.1 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Somatomedin_B PF01033.17 RUS82811.1 - 3e-05 24.3 14.3 9.3e-05 22.7 14.3 1.9 1 0 0 1 1 1 1 Somatomedin B domain DUF5387 PF17361.2 RUS82811.1 - 6.9 6.3 9.3 0.33 10.6 3.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5387) LeuA_dimer PF08502.10 RUS82812.1 - 0.015 15.2 0.9 0.026 14.4 0.9 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain REF PF05755.12 RUS82812.1 - 0.032 14.0 0.2 0.048 13.5 0.2 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Chlorosome_CsmC PF11098.8 RUS82812.1 - 0.059 13.3 7.7 0.036 14.1 3.3 2.5 1 1 1 2 2 2 0 Chlorosome envelope protein C HrpE PF06188.12 RUS82812.1 - 0.08 12.8 0.8 0.18 11.7 0.8 1.5 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.18 RUS82812.1 - 0.46 10.6 7.2 0.19 11.8 4.2 1.8 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.7 RUS82812.1 - 6 7.5 9.6 4.5 7.9 3.4 3.2 2 2 1 3 3 3 0 YtxH-like protein GpcrRhopsn4 PF10192.9 RUS82814.1 - 1.1e-62 211.8 17.3 1.4e-62 211.5 17.3 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RUS82814.1 - 8.3e-07 28.5 8.2 1.2e-06 28.0 8.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor RabGAP-TBC PF00566.18 RUS82815.1 - 2.4e-08 33.9 1.2 1.4e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 RUS82815.1 - 0.00019 21.9 0.0 0.00058 20.4 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Myosin_TH1 PF06017.13 RUS82815.1 - 0.00029 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding MFS_1 PF07690.16 RUS82817.1 - 4.1e-20 72.0 15.4 5.5e-20 71.6 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS82817.1 - 0.00016 20.7 9.4 0.00017 20.6 8.3 1.5 1 1 1 2 2 2 1 MFS_1 like family Nuc_H_symport PF03825.16 RUS82817.1 - 0.0079 15.2 8.1 0.011 14.8 8.1 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter Gate PF07670.14 RUS82817.1 - 0.011 16.0 0.0 0.43 10.9 0.0 2.9 1 1 1 2 2 2 0 Nucleoside recognition Sugar_tr PF00083.24 RUS82817.1 - 2.7 6.7 13.7 4.8 5.9 13.6 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 RUS82819.1 - 1.2e-27 96.8 12.4 6.6e-27 94.3 12.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 RUS82819.1 - 0.00079 18.8 4.9 0.095 12.0 1.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TonB_N PF16031.5 RUS82819.1 - 0.079 13.5 0.8 0.12 12.9 0.8 1.2 1 0 0 1 1 1 0 TonB polyproline region DUF2530 PF10745.9 RUS82819.1 - 4.5 7.6 9.4 22 5.4 3.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Aa_trans PF01490.18 RUS82820.1 - 3.5e-15 55.6 4.4 3.9e-15 55.5 4.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4870 PF09685.10 RUS82820.1 - 0.15 12.2 2.7 0.21 11.7 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) TPR_1 PF00515.28 RUS82821.1 - 3.2e-29 99.5 8.6 3.5e-06 26.6 0.4 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS82821.1 - 3.7e-26 89.1 7.9 0.00033 20.5 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 RUS82821.1 - 2.2e-14 52.4 19.2 0.00086 19.3 0.1 8.3 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS82821.1 - 2.2e-13 49.6 0.6 0.0032 17.1 0.1 6.6 5 2 2 7 7 7 2 TPR repeat TPR_14 PF13428.6 RUS82821.1 - 2.1e-11 43.7 7.4 0.031 15.1 0.1 8.4 7 2 3 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS82821.1 - 5.4e-11 42.1 0.8 0.018 15.4 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS82821.1 - 1.8e-10 41.1 3.2 0.0011 19.4 0.7 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS82821.1 - 2.6e-10 40.8 0.6 0.00017 22.1 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS82821.1 - 3.9e-10 39.9 5.8 0.037 14.3 0.0 6.3 6 1 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS82821.1 - 1.7e-09 37.0 0.9 0.16 12.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS82821.1 - 0.00055 19.7 1.1 0.27 11.2 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS82821.1 - 0.0034 17.6 11.1 0.035 14.3 0.1 4.8 4 1 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 RUS82821.1 - 0.025 14.8 2.5 12 6.4 0.1 4.0 4 0 0 4 4 3 0 PPR repeat SPO22 PF08631.10 RUS82821.1 - 0.051 13.1 0.2 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 RUS82821.1 - 0.052 14.2 9.6 26 5.8 0.3 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat MIT PF04212.18 RUS82821.1 - 2.5 8.2 12.2 0.75 9.9 2.5 4.2 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain LTD PF00932.19 RUS82822.1 - 1.2e-08 35.3 0.0 1.6e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Lamin Tail Domain C2 PF00168.30 RUS82823.1 - 3.3e-30 104.4 0.2 4.8e-16 58.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 RUS82823.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 ChapFlgA_N PF17656.1 RUS82824.1 - 1.2e-10 41.4 0.0 81 3.5 0.0 8.8 1 1 17 18 18 18 2 FlgA N-terminal domain Luteo_coat PF00894.18 RUS82824.1 - 0.0045 16.9 9.6 38 4.2 0.2 5.6 1 1 6 7 7 7 3 Luteovirus coat protein PITH PF06201.13 RUS82825.1 - 1.5e-36 125.9 0.0 2.3e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 RUS82825.1 - 5.4e-22 77.7 0.0 9.1e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS82825.1 - 1e-05 25.8 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RUS82825.1 - 3.7e-05 23.5 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RUS82825.1 - 0.00044 20.7 0.1 0.0011 19.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RUS82825.1 - 0.0023 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 RUS82825.1 - 0.0052 16.9 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 RUS82825.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Redoxin TraF PF13728.6 RUS82825.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.16 RUS82825.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 Podoplanin PF05808.11 RUS82826.1 - 1.3 9.1 9.8 1.8 8.6 9.5 1.4 1 1 0 1 1 1 0 Podoplanin DUF4195 PF13836.6 RUS82830.1 - 9.1 6.4 10.7 13 5.8 9.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4195) zf-H2C2_2 PF13465.6 RUS82831.1 - 2.3e-57 189.0 52.0 4.2e-09 36.4 0.3 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS82831.1 - 5.1e-35 118.0 62.8 1.4e-05 25.2 0.5 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS82831.1 - 2.7e-31 105.5 55.6 0.0005 20.7 0.7 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS82831.1 - 1.1e-21 76.3 59.8 0.0002 21.3 0.5 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS82831.1 - 7.3e-19 67.6 31.1 0.0086 16.3 0.1 8.3 7 1 1 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS82831.1 - 4e-10 39.7 42.4 0.036 14.5 0.4 8.3 8 0 0 8 8 8 6 Zinc-finger of C2H2 type GAGA PF09237.11 RUS82831.1 - 2.9e-09 36.6 0.7 1.8 8.4 0.0 6.0 3 1 3 6 6 6 3 GAGA factor BolA PF01722.18 RUS82831.1 - 0.076 13.3 6.1 7.2 7.0 0.1 4.3 2 1 2 4 4 4 0 BolA-like protein Zf_RING PF16744.5 RUS82831.1 - 0.12 12.5 25.0 26 5.0 0.4 7.5 1 1 7 8 8 8 0 KIAA1045 RING finger FYVE PF01363.21 RUS82831.1 - 0.19 11.9 33.3 0.44 10.7 8.0 5.1 2 2 1 3 3 3 0 FYVE zinc finger C1_2 PF03107.16 RUS82831.1 - 0.23 11.8 40.2 5.5 7.4 3.3 7.7 3 2 3 6 6 6 0 C1 domain C1_4 PF07975.12 RUS82831.1 - 1.3 9.3 29.0 0.58 10.4 4.0 5.2 1 1 4 5 5 5 0 TFIIH C1-like domain ADK_lid PF05191.14 RUS82831.1 - 7 6.7 22.3 9.5 6.3 0.4 5.7 4 3 0 4 4 4 0 Adenylate kinase, active site lid Ta0938 PF11494.8 RUS82831.1 - 8.4 6.7 20.0 1.9 8.8 2.0 5.3 1 1 4 5 5 5 0 Ta0938 zinc_ribbon_15 PF17032.5 RUS82831.1 - 8.5 7.2 24.7 22 5.9 2.2 4.4 1 1 5 6 6 6 0 zinc-ribbon family PPP4R2 PF09184.11 RUS82832.1 - 1.6 8.3 8.9 0.82 9.2 4.4 2.4 2 0 0 2 2 2 0 PPP4R2 Death PF00531.22 RUS82833.1 - 3.1e-06 27.3 0.3 4.3e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Death domain 7tm_1 PF00001.21 RUS82835.1 - 2.5e-09 36.9 5.6 7.7e-09 35.3 5.6 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1180 PF06679.12 RUS82835.1 - 0.12 12.8 4.9 0.68 10.3 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) 7tm_1 PF00001.21 RUS82836.1 - 1.2e-11 44.5 9.3 1.7e-11 43.9 9.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS82836.1 - 2.7e-11 43.6 6.0 2.7e-11 43.6 6.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS82836.1 - 2.6e-10 40.1 10.8 5.2e-10 39.1 10.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srbc PF10316.9 RUS82836.1 - 0.5 9.8 10.8 0.02 14.4 4.5 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc Thioredoxin_6 PF13848.6 RUS82837.1 - 5.1e-09 36.3 0.0 7.9e-08 32.4 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 RUS82837.1 - 5.6e-09 35.9 0.0 0.012 15.6 0.0 3.4 2 1 1 3 3 3 3 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 RUS82837.1 - 6.7e-09 35.7 0.0 8.6e-05 22.5 0.0 3.3 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 RUS82837.1 - 4.6e-06 27.0 0.0 0.28 11.6 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 RUS82837.1 - 0.00021 20.7 0.0 0.012 14.9 0.0 3.1 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 RUS82837.1 - 0.00022 21.2 0.0 0.041 13.9 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin domain RBFA PF02033.18 RUS82837.1 - 0.011 16.2 0.1 15 6.1 0.0 3.1 3 0 0 3 3 3 0 Ribosome-binding factor A TrbC_Ftype PF09673.10 RUS82837.1 - 0.011 15.7 0.0 38 4.4 0.0 3.2 1 1 2 3 3 3 0 Type-F conjugative transfer system pilin assembly protein DUF836 PF05768.14 RUS82837.1 - 0.027 14.9 0.0 0.4 11.1 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) CYTH PF01928.21 RUS82837.1 - 0.082 12.8 0.0 0.63 9.9 0.0 2.0 1 1 0 1 1 1 0 CYTH domain TraF PF13728.6 RUS82837.1 - 0.16 11.8 0.0 52 3.5 0.0 3.4 2 1 1 3 3 3 0 F plasmid transfer operon protein Ig_2 PF13895.6 RUS82838.1 - 2.8e-11 43.6 1.2 0.0004 20.7 0.1 3.0 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 RUS82838.1 - 1.5e-09 38.3 3.0 4.6e-05 23.9 0.1 4.3 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 RUS82838.1 - 0.00048 20.1 0.0 0.96 9.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain SelB-wing_2 PF09106.11 RUS82840.1 - 0.031 14.5 0.8 2.6 8.3 0.8 2.7 1 1 0 1 1 1 0 Elongation factor SelB, winged helix RBDV_coat PF06593.11 RUS82840.1 - 0.45 9.9 4.4 2.7 7.4 0.6 2.2 1 1 1 2 2 2 0 Raspberry bushy dwarf virus coat protein PI3_PI4_kinase PF00454.27 RUS82841.1 - 3.7e-66 223.5 0.1 4.4e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RUS82841.1 - 4.3e-17 61.6 0.7 1.1e-16 60.4 0.7 1.7 1 0 0 1 1 1 1 FATC domain SICA_C PF12879.7 RUS82841.1 - 0.047 13.7 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain PP_kinase_C PF13090.6 RUS82842.1 - 4.2e-08 32.8 12.5 3.7 7.0 0.1 6.7 1 1 6 7 7 7 5 Polyphosphate kinase C-terminal domain 2 Ephrin PF00812.17 RUS82842.1 - 0.00033 20.7 11.4 3.3 7.7 0.1 5.7 1 1 5 6 6 6 2 Ephrin PDZ_1 PF12812.7 RUS82842.1 - 0.00049 20.0 0.1 17 5.5 0.0 4.5 1 1 6 7 7 7 1 PDZ-like domain DUF4278 PF14105.6 RUS82842.1 - 0.01 16.3 0.7 1.9 8.9 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4278) DUF3663 PF12404.8 RUS82842.1 - 0.038 14.0 0.4 22 5.2 0.0 3.3 1 1 1 4 4 4 0 Peptidase Ribosom_S30AE_C PF16321.5 RUS82842.1 - 0.74 9.5 6.2 1.1e+02 2.6 0.0 4.6 1 1 5 6 6 6 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Fimbrillin_C PF15495.6 RUS82842.1 - 8.3 6.9 11.1 2.6e+02 2.1 0.4 3.5 1 1 1 2 2 2 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal AA_permease_2 PF13520.6 RUS82843.1 - 1.5e-39 136.0 34.4 1.5e-39 136.0 34.4 2.2 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RUS82843.1 - 2.8e-29 102.1 38.5 2.8e-29 102.1 38.5 1.5 2 0 0 2 2 2 1 Amino acid permease PspB PF06667.12 RUS82844.1 - 0.00094 19.2 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Phage shock protein B Ac76 PF05814.11 RUS82844.1 - 0.051 13.6 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Orf76 (Ac76) NDUF_B4 PF07225.12 RUS82844.1 - 0.074 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) AvrPto PF11592.8 RUS82844.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Vpu PF00558.19 RUS82844.1 - 0.23 11.2 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Vpu protein DSL PF01414.19 RUS82844.1 - 0.31 11.4 0.2 0.31 11.4 0.2 5.6 1 1 5 6 6 6 0 Delta serrate ligand YebO PF13974.6 RUS82844.1 - 0.34 11.0 0.4 0.56 10.3 0.4 1.3 1 0 0 1 1 1 0 YebO-like protein Helicase_C PF00271.31 RUS82845.1 - 5.2e-18 65.4 0.0 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 RUS82845.1 - 1.4e-17 63.8 0.0 2.6e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RUS82845.1 - 9.8e-16 58.0 0.0 9.8e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 RUS82845.1 - 1e-09 38.4 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS82845.1 - 0.0039 17.5 0.6 0.85 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS82845.1 - 0.008 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS82845.1 - 0.073 13.4 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 RUS82845.1 - 0.077 12.3 0.6 0.26 10.6 0.1 2.1 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 RUS82845.1 - 0.083 12.9 0.2 1.6 8.7 0.2 2.6 1 1 0 1 1 1 0 AAA domain DUF4615 PF15393.6 RUS82846.1 - 1.6e-32 113.0 1.6 2e-32 112.7 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) V-SNARE PF05008.15 RUS82846.1 - 0.071 13.5 1.6 13 6.2 0.5 2.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3682 PF12446.8 RUS82846.1 - 3.1 8.3 10.8 4.7 7.7 9.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Zds_C PF08632.10 RUS82847.1 - 0.077 12.8 1.8 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term APC_N_CC PF16689.5 RUS82848.1 - 0.00026 21.0 2.1 0.00056 19.9 2.1 1.7 1 1 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain Tektin PF03148.14 RUS82848.1 - 0.00043 19.1 4.3 0.00051 18.9 4.3 1.0 1 0 0 1 1 1 1 Tektin family Herpes_UL6 PF01763.16 RUS82848.1 - 0.0087 14.6 1.3 0.0099 14.4 1.3 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like APG6_N PF17675.1 RUS82848.1 - 0.013 16.0 5.9 0.015 15.9 5.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 RUS82848.1 - 0.018 15.1 6.3 0.45 10.6 0.3 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation P53_C PF11619.8 RUS82848.1 - 0.021 14.9 0.1 0.035 14.2 0.1 1.5 1 1 0 1 1 1 0 Transcription factor P53 - C terminal domain TMF_TATA_bd PF12325.8 RUS82848.1 - 0.03 14.5 7.3 0.073 13.3 7.1 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 RUS82848.1 - 0.055 13.4 7.0 0.33 11.0 1.1 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF2312 PF10073.9 RUS82848.1 - 0.061 13.0 0.8 0.08 12.6 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) LPP PF04728.13 RUS82848.1 - 0.061 13.7 3.1 4.2 7.8 3.1 2.3 1 1 0 1 1 1 0 Lipoprotein leucine-zipper HALZ PF02183.18 RUS82848.1 - 0.13 12.5 5.7 0.64 10.3 1.1 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper AAA_9 PF12781.7 RUS82848.1 - 0.18 10.9 3.5 0.2 10.7 3.5 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region YabA PF06156.13 RUS82848.1 - 0.57 10.8 4.1 0.76 10.4 4.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 RUS82848.1 - 0.81 9.5 7.2 5.1 6.9 4.3 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 RUS82848.1 - 1.7 9.2 7.2 22 5.6 7.2 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rap_GAP PF02145.15 RUS82849.1 - 5.1e-57 192.4 0.0 6.5e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP LIM PF00412.22 RUS82851.1 - 9e-06 25.8 0.5 1.5e-05 25.1 0.5 1.3 1 0 0 1 1 1 1 LIM domain Fungal_KA1 PF16797.5 RUS82851.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Spt20 PF12090.8 RUS82852.1 - 0.00028 20.6 34.6 0.00047 19.8 34.6 1.3 1 0 0 1 1 1 1 Spt20 family DDHD PF02862.17 RUS82852.1 - 0.00078 19.7 3.9 0.0013 19.0 3.9 1.4 1 0 0 1 1 1 1 DDHD domain EPL1 PF10513.9 RUS82852.1 - 0.011 16.1 9.1 0.011 16.1 9.1 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Pex14_N PF04695.13 RUS82852.1 - 0.013 16.2 13.6 0.013 16.2 13.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 RUS82852.1 - 0.023 15.7 12.1 0.023 15.7 12.1 2.4 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) SET PF00856.28 RUS82852.1 - 0.033 14.6 0.2 0.053 13.9 0.2 1.4 1 0 0 1 1 1 0 SET domain PAT1 PF09770.9 RUS82852.1 - 0.036 12.3 16.4 0.046 12.0 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CTU2 PF10288.9 RUS82852.1 - 0.055 13.7 7.4 0.12 12.7 7.4 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 GREB1 PF15782.5 RUS82852.1 - 0.058 10.5 13.1 0.071 10.2 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5308 PF17233.2 RUS82852.1 - 0.068 13.4 7.3 0.023 14.9 4.1 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5308) SLC12 PF03522.15 RUS82852.1 - 0.092 11.8 8.7 0.14 11.2 8.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF702 PF05142.12 RUS82852.1 - 0.14 12.7 9.9 0.29 11.6 9.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Eapp_C PF10238.9 RUS82852.1 - 0.19 11.8 15.1 0.19 11.8 11.2 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 RUS82852.1 - 0.19 11.5 13.0 0.27 11.0 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 RUS82852.1 - 0.23 9.7 7.3 0.3 9.3 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RUS82852.1 - 0.27 10.0 10.8 0.39 9.5 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 RUS82852.1 - 0.29 10.5 16.4 0.55 9.6 16.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPL5 PF18168.1 RUS82852.1 - 0.33 10.2 6.7 0.54 9.5 6.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Androgen_recep PF02166.16 RUS82852.1 - 0.33 9.8 25.4 0.63 8.8 25.4 1.4 1 0 0 1 1 1 0 Androgen receptor eIF-3_zeta PF05091.12 RUS82852.1 - 0.47 9.4 17.4 0.69 8.8 17.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TRAPPC-Trs85 PF12739.7 RUS82852.1 - 0.68 8.8 11.0 1.2 8.1 11.0 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1764 PF08576.10 RUS82852.1 - 0.79 10.7 14.3 2 9.4 14.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Connexin PF00029.19 RUS82852.1 - 0.91 9.2 10.1 1.9 8.2 10.1 1.5 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 RUS82852.1 - 0.94 9.9 13.4 0.062 13.7 8.1 1.8 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex PBP1_TM PF14812.6 RUS82852.1 - 1.1 9.7 7.3 4 7.9 7.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gti1_Pac2 PF09729.9 RUS82852.1 - 1.5 8.9 11.7 3.4 7.7 11.7 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family YABBY PF04690.13 RUS82852.1 - 1.6 9.2 16.3 24 5.4 0.0 2.6 2 0 0 2 2 2 0 YABBY protein Band_3_cyto PF07565.13 RUS82852.1 - 1.8 8.3 13.2 3.1 7.5 13.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Otopetrin PF03189.13 RUS82852.1 - 2.1 7.0 4.4 3.2 6.5 4.4 1.2 1 0 0 1 1 1 0 Otopetrin Paf1 PF03985.13 RUS82852.1 - 2.2 7.2 18.2 3.8 6.4 18.2 1.3 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 RUS82852.1 - 2.5 7.0 8.6 3.6 6.5 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2076 PF09849.9 RUS82852.1 - 2.7 8.0 28.7 0.061 13.4 21.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SpoIIP PF07454.11 RUS82852.1 - 4.1 6.8 21.3 0.022 14.2 11.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 RUS82852.1 - 4.2 5.4 12.6 5.8 4.9 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PepSY_TM PF03929.16 RUS82852.1 - 4.7 6.8 6.1 5.1 6.7 4.5 1.7 2 0 0 2 2 2 0 PepSY-associated TM region DUF4770 PF15994.5 RUS82852.1 - 4.7 7.4 17.7 8.4 6.6 17.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) NARP1 PF12569.8 RUS82852.1 - 5.3 5.8 15.0 7.3 5.4 15.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3408 PF11888.8 RUS82852.1 - 5.5 7.1 16.5 14 5.8 16.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Serinc PF03348.15 RUS82852.1 - 5.5 5.8 6.6 9.9 5.0 6.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pannexin_like PF12534.8 RUS82852.1 - 5.6 5.9 9.9 10 5.1 9.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Tim54 PF11711.8 RUS82852.1 - 6 5.5 16.0 8.9 5.0 16.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 RUS82852.1 - 6.1 5.6 10.2 9 5.0 10.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2722 PF10846.8 RUS82852.1 - 8.2 5.3 37.6 16 4.3 37.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) UPF0560 PF10577.9 RUS82852.1 - 9.1 4.6 19.3 14 4.0 19.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Zip PF02535.22 RUS82852.1 - 9.8 5.3 6.4 15 4.7 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DSL PF01414.19 RUS82853.1 - 2.4e-11 43.7 16.1 4.3e-11 42.9 6.5 2.6 2 0 0 2 2 2 2 Delta serrate ligand MNNL PF07657.13 RUS82853.1 - 8.8e-06 25.7 0.3 8.8e-06 25.7 0.3 2.5 3 0 0 3 3 3 1 N terminus of Notch ligand EGF PF00008.27 RUS82853.1 - 0.015 15.5 9.9 0.015 15.5 9.9 3.3 3 2 1 4 4 4 0 EGF-like domain SCF PF02404.15 RUS82853.1 - 0.041 13.2 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor Ice_nucleation PF00818.17 RUS82853.1 - 9.3 6.6 8.0 2.1 8.6 1.6 2.9 2 0 0 2 2 2 0 Ice nucleation protein repeat DSL PF01414.19 RUS82854.1 - 5.1e-11 42.7 0.6 9.8e-11 41.8 0.6 1.5 1 0 0 1 1 1 1 Delta serrate ligand MNNL PF07657.13 RUS82854.1 - 9.7e-06 25.5 0.2 9.7e-06 25.5 0.2 1.7 2 0 0 2 2 2 1 N terminus of Notch ligand HA2 PF04408.23 RUS82855.1 - 6.5e-17 61.8 0.1 1.3e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RUS82855.1 - 1.9e-16 60.2 0.0 6.3e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RUS82855.1 - 9.6e-13 48.5 0.0 2.1e-12 47.4 0.1 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS82856.1 - 2.5e-13 50.2 0.0 5.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RUS82856.1 - 4.9e-05 23.6 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RUS82856.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 RUS82856.1 - 0.0078 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 RUS82856.1 - 0.033 14.7 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 RUS82856.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRTP PF01366.18 RUS82856.1 - 0.057 11.5 1.1 0.06 11.4 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus processing and transport protein dsRBD2 PF17842.1 RUS82856.1 - 0.058 13.6 0.1 0.29 11.3 0.1 2.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 FtsK_SpoIIIE PF01580.18 RUS82856.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pkinase PF00069.25 RUS82857.1 - 7.3e-65 218.9 0.0 1.2e-64 218.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS82857.1 - 6.4e-30 104.3 0.0 1.1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS82857.1 - 4.9e-06 26.1 0.5 9.9e-05 21.8 0.1 2.2 1 1 1 2 2 2 1 Kinase-like B12D PF06522.11 RUS82860.1 - 2.2e-09 36.9 0.2 5.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2733 PF10813.8 RUS82861.1 - 0.088 12.6 0.1 0.088 12.6 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) FAM176 PF14851.6 RUS82863.1 - 0.17 11.5 3.8 0.25 11.0 3.8 1.1 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 RUS82863.1 - 0.58 9.0 4.6 0.79 8.6 4.6 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4820 PF16091.5 RUS82863.1 - 0.74 9.1 2.4 1 8.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 RUS82863.1 - 2.1 7.6 4.4 3.1 7.0 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 RUS82863.1 - 6.2 5.5 4.8 8.4 5.1 4.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Drf_FH1 PF06346.12 RUS82864.1 - 3.4e-05 23.6 73.2 0.038 13.7 38.6 2.6 1 1 1 2 2 2 2 Formin Homology Region 1 LRR_6 PF13516.6 RUS82865.1 - 1.9e-12 46.2 0.7 0.00022 21.1 0.0 3.3 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 RUS82865.1 - 0.023 15.2 1.0 4.2 8.3 1.0 2.6 1 1 0 1 1 1 0 Leucine Rich Repeat Herpes_BLLF1 PF05109.13 RUS82866.1 - 4.2e-05 21.8 16.8 4.7e-05 21.6 16.8 1.0 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Peptidase_M60_C PF18630.1 RUS82866.1 - 0.0015 18.6 1.2 7.9 6.7 0.1 3.2 1 1 2 3 3 3 2 Peptidase M60 C-terminal domain DUF4744 PF15918.5 RUS82866.1 - 0.11 13.3 19.9 1.9 9.4 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) DUF5109 PF17134.4 RUS82866.1 - 0.99 9.3 8.2 11 6.0 0.3 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5109) DEC-1_C PF04626.13 RUS82866.1 - 6.3 7.2 11.8 0.94 9.9 2.3 2.1 1 1 1 2 2 2 0 Dec-1 protein, C terminal region DUF5381 PF17353.2 RUS82867.1 - 1.3 8.8 5.8 23 4.7 0.1 3.3 1 1 1 2 2 2 0 Family of unknown function (DUF5381) DUF2171 PF09939.9 RUS82869.1 - 0.011 16.0 8.5 2.5 8.4 0.3 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2171) Fibrinogen_BP PF08017.11 RUS82869.1 - 0.13 10.7 0.0 0.44 8.9 0.0 1.7 1 1 0 1 1 1 0 Fibrinogen binding protein FAD_binding_5 PF00941.21 RUS82870.1 - 0.77 9.5 21.1 4.4 7.0 3.0 3.4 1 1 2 3 3 3 0 FAD binding domain in molybdopterin dehydrogenase PMG PF05287.12 RUS82871.1 - 0.4 10.7 18.4 0.26 11.3 10.6 2.2 1 1 1 2 2 2 0 PMG protein Ank_2 PF12796.7 RUS82872.1 - 1.3e-86 285.3 18.6 6.3e-15 55.5 0.3 7.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 RUS82872.1 - 4.8e-76 248.1 28.3 8.5e-06 26.0 0.0 15.1 14 1 1 15 15 15 15 Ankyrin repeat Ank_4 PF13637.6 RUS82872.1 - 1.1e-70 233.1 20.3 2.5e-06 27.9 0.1 13.9 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS82872.1 - 7.6e-68 223.7 31.5 6e-09 36.0 0.1 12.6 2 2 12 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS82872.1 - 6.7e-62 198.1 11.9 0.0015 18.8 0.0 15.2 15 0 0 15 15 15 15 Ankyrin repeat VWA_3_C PF18571.1 RUS82872.1 - 7.2e-07 29.0 11.4 0.41 10.5 0.0 7.6 9 0 0 9 9 9 2 von Willebrand factor type A C-terminal domain DUF664 PF04978.12 RUS82872.1 - 0.0019 18.7 2.9 4.5 7.7 0.0 5.1 2 1 4 6 6 6 1 Protein of unknown function (DUF664) DUF2122 PF09895.9 RUS82872.1 - 0.0068 16.8 0.1 1.1e+02 3.3 0.0 5.2 6 1 0 6 6 6 0 RecB-family nuclease (DUF2122) DUF5398 PF17376.2 RUS82873.1 - 6.2e-23 81.2 117.9 58 4.4 0.1 35.2 1 1 56 57 57 57 56 Family of unknown function (DUF5398) Lectin_C PF00059.21 RUS82874.1 - 1.6e-11 44.9 0.4 2.4e-11 44.3 0.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain Cytochrom_C_2 PF01322.20 RUS82875.1 - 0.045 14.7 5.5 16 6.4 0.4 3.2 1 1 2 4 4 4 0 Cytochrome C' RES PF08808.11 RUS82875.1 - 1.3 8.9 19.6 32 4.4 5.7 3.5 1 1 1 2 2 2 0 RES domain DUF3340 PF11818.8 RUS82875.1 - 1.8 8.7 23.0 1.6 8.9 7.2 2.4 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Yuri_gagarin PF15934.5 RUS82875.1 - 2 8.2 12.3 9.6 6.0 1.7 2.3 1 1 0 2 2 2 0 Yuri gagarin p450 PF00067.22 RUS82876.1 - 9e-74 248.9 0.0 1.3e-73 248.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 RUS82877.1 - 5.8e-50 169.9 0.0 5.8e-50 169.9 0.0 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Sds3 PF08598.11 RUS82877.1 - 1.4 8.9 9.2 0.034 14.1 1.1 2.2 3 0 0 3 3 3 0 Sds3-like SIR2 PF02146.17 RUS82878.1 - 1.8e-27 96.4 0.6 1.4e-19 70.7 0.1 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 RUS82878.1 - 1.4e-05 24.9 0.1 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF4512 PF14975.6 RUS82879.1 - 4.4e-08 33.8 12.2 4.2e-07 30.6 12.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) DUF229 PF02995.17 RUS82880.1 - 1.4e-77 261.4 0.0 2e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS82880.1 - 3.9e-05 23.2 0.2 0.00027 20.5 0.0 2.1 1 1 0 2 2 2 1 Sulfatase Ribosomal_L36 PF00444.18 RUS82880.1 - 0.097 12.9 4.3 0.18 12.0 4.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L36 DUF4512 PF14975.6 RUS82881.1 - 4.6e-11 43.3 9.7 2.6e-10 40.9 9.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) TED_complement PF07678.14 RUS82883.1 - 6.7e-65 219.2 0.0 9.1e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 RUS82883.1 - 6.3e-34 117.3 0.1 2.6e-30 105.6 0.0 2.9 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 RUS82883.1 - 1.2e-26 92.4 0.3 4e-26 90.7 0.1 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 RUS82883.1 - 1.2e-22 79.9 0.0 3.5e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 RUS82883.1 - 5.8e-17 61.9 0.1 3.1e-16 59.6 0.0 2.2 2 0 0 2 2 2 1 MG2 domain MG4 PF17789.1 RUS82883.1 - 2.4e-12 46.8 0.4 7.7e-11 42.0 0.0 3.0 3 0 0 3 3 3 1 Macroglobulin domain MG4 SVA PF05326.11 RUS82883.1 - 0.022 14.7 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) DUF4643 PF15485.6 RUS82884.1 - 4.6 7.0 11.8 0.63 9.8 7.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4643) zf-C2H2 PF00096.26 RUS82885.1 - 4.9e-28 96.0 56.3 0.00016 21.9 0.8 8.5 8 1 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS82885.1 - 1.8e-27 93.6 48.3 0.00014 22.4 0.8 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS82885.1 - 8.6e-21 73.4 51.8 1e-06 28.9 0.3 8.4 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS82885.1 - 4.6e-16 58.6 32.8 0.031 14.6 0.5 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS82885.1 - 7.8e-12 45.2 40.3 0.056 13.9 0.2 8.6 8 1 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS82885.1 - 6.8e-11 41.9 54.2 3.1e-05 23.8 0.3 8.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS82885.1 - 2.5e-05 23.9 32.8 0.13 12.1 1.6 7.6 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 RUS82885.1 - 0.00046 20.8 17.1 0.29 11.8 2.9 4.0 2 2 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 RUS82885.1 - 0.001 19.1 1.3 0.001 19.1 1.3 6.0 6 1 1 7 7 6 2 Zinc ribbon domain zf_UBZ PF18439.1 RUS82885.1 - 0.0068 16.0 30.2 0.24 11.0 0.2 7.6 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3 PF13878.6 RUS82885.1 - 0.025 14.4 0.9 0.025 14.4 0.9 5.8 5 1 2 7 7 7 0 zinc-finger of acetyl-transferase ESCO zf-LYAR PF08790.11 RUS82885.1 - 0.053 13.4 0.9 0.053 13.4 0.9 6.4 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 RUS82885.1 - 0.097 13.0 31.9 6.4 7.2 0.1 6.8 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 RUS82885.1 - 0.21 11.3 0.1 0.21 11.3 0.1 3.8 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain Elf1 PF05129.13 RUS82885.1 - 0.25 11.4 27.2 0.64 10.1 0.8 4.9 2 2 3 5 5 5 0 Transcription elongation factor Elf1 like DZR PF12773.7 RUS82885.1 - 0.55 10.3 28.4 0.54 10.3 1.5 5.0 1 1 2 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 RUS82885.1 - 0.85 10.4 25.2 0.62 10.9 4.7 4.2 1 1 3 5 5 5 0 zinc-ribbon family CxC3 PF18804.1 RUS82885.1 - 1.1 9.2 10.5 0.063 13.1 0.8 2.9 3 0 0 3 3 2 0 CxC3 like cysteine cluster associated with KDZ transposases FYDLN_acid PF09538.10 RUS82885.1 - 1.2 9.9 10.5 29 5.4 4.7 4.5 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) HypA PF01155.19 RUS82885.1 - 1.3 9.0 23.6 1.3 9.1 1.1 4.3 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 RUS82885.1 - 1.6 8.8 21.6 8.3 6.5 0.3 5.2 3 2 3 6 6 5 0 CpXC protein zf-AN1 PF01428.16 RUS82885.1 - 1.9 8.7 30.4 24 5.2 0.1 7.3 7 0 0 7 7 7 0 AN1-like Zinc finger ADK_lid PF05191.14 RUS82885.1 - 2.5 8.2 33.8 0.3 11.1 1.0 5.8 4 1 3 7 7 7 0 Adenylate kinase, active site lid DUF4428 PF14471.6 RUS82885.1 - 2.5 8.1 15.5 4.4 7.3 0.0 4.8 4 1 1 5 5 4 0 Domain of unknown function (DUF4428) zf-CCHC_2 PF13696.6 RUS82885.1 - 5.8 6.8 21.5 1.1 9.1 0.3 5.2 5 0 0 5 5 5 0 Zinc knuckle zf-C2H2_8 PF15909.5 RUS82885.1 - 6.1 7.2 21.6 0.13 12.5 1.7 3.8 1 1 4 5 5 4 0 C2H2-type zinc ribbon zf-RING_7 PF02591.15 RUS82885.1 - 8.4 6.7 16.3 13 6.0 0.1 4.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain Homeodomain PF00046.29 RUS82886.1 - 7.4e-21 73.8 5.7 1.3e-20 73.0 5.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS82886.1 - 0.01 15.7 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 RUS82886.1 - 0.085 12.3 0.3 0.085 12.3 0.3 2.4 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Lectin_C PF00059.21 RUS82887.1 - 2.3e-11 44.4 0.2 2.6e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain MBOAT PF03062.19 RUS82888.1 - 2.9e-41 142.0 29.9 4.1e-41 141.5 29.8 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family GCN5L1 PF06320.13 RUS82888.1 - 0.26 11.5 0.6 0.46 10.6 0.6 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) zf-C4 PF00105.18 RUS82889.1 - 5e-28 97.3 14.4 1.3e-27 96.0 14.4 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS82889.1 - 1.1e-20 74.2 0.0 2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 7tm_1 PF00001.21 RUS82891.1 - 1.8e-50 171.8 13.2 2.3e-50 171.4 13.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS82891.1 - 8.6e-15 54.8 8.6 1.5e-14 54.0 8.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS82891.1 - 2.6e-08 33.8 10.0 4.8e-08 33.0 10.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS82891.1 - 4e-08 33.4 12.2 9.3e-08 32.1 11.2 2.0 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 RUS82891.1 - 2.1e-06 27.3 15.9 0.00058 19.2 6.1 2.9 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF1980 PF09323.10 RUS82891.1 - 0.041 13.8 0.1 0.041 13.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TGF_beta PF00019.20 RUS82893.1 - 3.3e-13 50.5 0.1 6.5e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Transforming growth factor beta like domain MMS19_N PF14500.6 RUS82896.1 - 1.2e-75 254.5 9.1 4.4e-75 252.6 0.0 4.6 4 2 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 RUS82896.1 - 3.3e-55 187.9 25.3 4.6e-55 187.4 9.9 3.4 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 RUS82896.1 - 7.4e-07 29.5 2.7 0.011 16.1 0.1 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 RUS82896.1 - 0.00065 20.1 3.1 4.4 7.9 0.2 5.1 4 0 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 RUS82896.1 - 0.02 15.1 4.7 0.8 9.9 0.0 4.9 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 RUS82896.1 - 0.047 14.0 12.5 0.15 12.4 0.1 6.0 7 0 0 7 7 7 0 HEAT repeat Bcl-2 PF00452.19 RUS82896.1 - 0.069 13.8 0.0 0.95 10.2 0.0 3.0 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family NOC3p PF07540.11 RUS82897.1 - 1.7e-25 89.2 0.1 1.7e-25 89.2 0.1 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein ABC_membrane PF00664.23 RUS82898.1 - 5.8e-35 121.3 4.4 8.3e-35 120.8 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS82898.1 - 1.6e-30 106.4 0.0 2.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS82898.1 - 3.8e-06 26.5 0.0 0.00075 19.0 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS82898.1 - 0.016 15.2 0.1 0.038 14.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 RUS82898.1 - 0.025 14.3 0.5 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 RUS82898.1 - 0.034 13.0 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 RUS82898.1 - 0.043 13.6 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.23 RUS82898.1 - 0.16 12.0 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 RUS82898.1 - 0.19 11.8 0.7 0.35 10.9 0.7 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Toxin_TOLIP PF00087.21 RUS82899.1 - 0.16 12.2 20.1 0.93 9.8 20.1 2.1 1 1 0 1 1 1 0 Snake toxin and toxin-like protein Sugar_tr PF00083.24 RUS82900.1 - 5.9e-15 55.1 6.1 5.9e-15 55.1 6.1 2.2 1 1 1 2 2 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS82900.1 - 2.9e-13 49.5 17.2 2.9e-13 49.5 17.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1387 PF07139.11 RUS82900.1 - 0.0016 18.3 18.2 0.0023 17.7 18.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) CLN3 PF02487.17 RUS82900.1 - 0.0019 17.3 0.1 0.0019 17.3 0.1 1.8 2 0 0 2 2 2 1 CLN3 protein Connexin PF00029.19 RUS82900.1 - 0.0047 16.7 6.6 0.013 15.3 6.6 1.7 1 0 0 1 1 1 1 Connexin Vfa1 PF08432.10 RUS82900.1 - 0.009 16.4 15.3 0.015 15.6 15.3 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 ORC_WH_C PF18137.1 RUS82900.1 - 0.025 14.7 6.6 0.058 13.5 6.6 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF2347 PF09804.9 RUS82900.1 - 0.028 14.0 6.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Rxt3 PF08642.10 RUS82900.1 - 0.036 14.8 1.1 0.083 13.7 1.1 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF4834 PF16118.5 RUS82900.1 - 0.039 14.9 0.6 0.039 14.9 0.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) G0-G1_switch_2 PF15103.6 RUS82900.1 - 0.056 13.9 0.3 0.056 13.9 0.3 3.6 4 1 1 5 5 3 0 G0/G1 switch protein 2 FHIPEP PF00771.20 RUS82900.1 - 0.06 11.8 0.1 0.096 11.1 0.1 1.2 1 0 0 1 1 1 0 FHIPEP family MMM1 PF10296.9 RUS82900.1 - 0.09 11.8 3.2 0.19 10.7 3.2 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Peroxin-13_N PF04088.13 RUS82900.1 - 0.11 12.8 1.9 0.26 11.6 1.9 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MFS_2 PF13347.6 RUS82900.1 - 0.11 11.1 10.2 0.0097 14.5 2.6 2.7 2 1 0 2 2 2 0 MFS/sugar transport protein DUF4770 PF15994.5 RUS82900.1 - 0.21 11.8 11.6 0.43 10.8 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) EIIBC-GUT_N PF03612.14 RUS82900.1 - 0.23 11.2 6.8 0.48 10.1 6.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF5313 PF17240.2 RUS82900.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5313) Peptidase_S49_N PF08496.10 RUS82900.1 - 0.34 11.0 18.5 1.1 9.4 18.5 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HA2 PF04408.23 RUS82900.1 - 0.37 11.1 3.4 0.47 10.8 1.8 2.0 2 0 0 2 2 1 0 Helicase associated domain (HA2) EOS1 PF12326.8 RUS82900.1 - 0.46 10.4 7.7 0.45 10.4 6.5 1.7 1 1 0 1 1 1 0 N-glycosylation protein MTP18 PF10558.9 RUS82900.1 - 0.47 10.4 2.9 1.1 9.2 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Sec62 PF03839.16 RUS82900.1 - 0.52 9.8 15.0 1.3 8.4 15.0 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Afi1 PF07792.12 RUS82900.1 - 1.2 9.7 8.2 0.38 11.2 5.3 1.6 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNApol_Exo PF18136.1 RUS82900.1 - 1.4 8.0 8.5 2.5 7.2 8.5 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF3899 PF13038.6 RUS82900.1 - 1.6 9.3 7.5 20 5.8 7.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) GNAT_acetyltr_2 PF13718.6 RUS82900.1 - 1.6 8.1 4.6 3.2 7.1 4.6 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Jak1_Phl PF17887.1 RUS82900.1 - 1.7 8.6 14.6 5.3 7.0 14.6 1.8 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Folate_carrier PF01770.18 RUS82900.1 - 3.2 6.4 12.8 0.13 11.0 5.5 2.2 1 1 2 3 3 3 0 Reduced folate carrier CDC45 PF02724.14 RUS82900.1 - 4.6 5.4 10.3 6.2 5.0 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PcfK PF14058.6 RUS82900.1 - 7.4 6.9 23.1 17 5.7 23.1 1.5 1 0 0 1 1 1 0 PcfK-like protein AF-4 PF05110.13 RUS82900.1 - 9.3 4.2 20.5 13 3.7 20.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sugar_tr PF00083.24 RUS82901.1 - 5.7e-16 58.4 26.8 8.4e-16 57.9 26.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS82901.1 - 5.7e-15 55.1 37.8 9.2e-15 54.4 37.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_1 PF00001.21 RUS82902.1 - 9.2e-54 182.5 26.5 1.3e-53 182.1 26.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS82902.1 - 1.5e-10 40.9 25.3 2.2e-10 40.4 25.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS82902.1 - 2.1e-08 34.3 24.6 4.6e-08 33.1 24.6 1.6 1 1 0 1 1 1 1 Olfactory receptor Ion_trans PF00520.31 RUS82903.1 - 7.2e-42 143.3 51.9 1.5e-25 89.9 32.7 2.1 2 0 0 2 2 2 2 Ion transport protein NUDIX PF00293.28 RUS82904.1 - 7.9e-08 32.4 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain RE_SinI PF09570.10 RUS82904.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease MIF PF01187.18 RUS82905.1 - 3.6e-25 88.5 0.0 4.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RUS82905.1 - 0.0047 16.8 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 Tautomerase enzyme E1-E2_ATPase PF00122.20 RUS82906.1 - 8.2e-54 181.9 0.6 8.2e-54 181.9 0.6 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RUS82906.1 - 5.5e-44 150.1 4.3 1.4e-43 148.8 4.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RUS82906.1 - 1.5e-21 77.6 0.0 5.2e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RUS82906.1 - 2.8e-21 75.4 0.0 5.3e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RUS82906.1 - 1.1e-20 73.0 0.0 4.7e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RUS82906.1 - 1.4e-06 28.3 0.8 2.5e-05 24.2 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS82906.1 - 1.6e-06 28.7 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 RUS82906.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Cupin_8 PF13621.6 RUS82910.1 - 1.8e-34 119.6 4.7 2.4e-34 119.2 0.1 2.3 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 RUS82910.1 - 6.2e-07 29.8 1.0 9.9e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RUS82910.1 - 4e-06 26.5 0.0 1.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein ABC2_membrane_3 PF12698.7 RUS82911.1 - 1.3e-56 192.2 39.5 3e-40 138.4 14.3 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 RUS82911.1 - 3e-53 180.0 0.1 3.6e-27 95.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS82911.1 - 1.9e-19 70.6 0.0 8.9e-07 29.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 RUS82911.1 - 1.4e-06 28.9 0.0 0.032 15.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 RUS82911.1 - 4.3e-05 23.1 0.0 3.6 7.0 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS82911.1 - 4.9e-05 23.9 3.2 0.1 13.1 0.5 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RUS82911.1 - 0.0011 18.8 0.0 0.61 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 RUS82911.1 - 0.0014 18.0 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 RUS82911.1 - 0.0025 18.0 0.0 5.5 7.3 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 RUS82911.1 - 0.0057 16.4 0.3 4.9 6.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RUS82911.1 - 0.0095 15.7 3.2 0.26 11.1 0.5 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS82911.1 - 0.012 15.5 0.7 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 RUS82911.1 - 0.014 15.6 0.5 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RUS82911.1 - 0.025 14.5 0.4 7.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 RUS82911.1 - 0.063 12.9 4.2 1.1 8.8 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Lum_binding PF00677.17 RUS82911.1 - 0.071 13.1 0.0 7.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Lumazine binding domain MukB PF04310.12 RUS82911.1 - 0.1 12.4 2.8 0.5 10.1 0.5 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA PF00004.29 RUS82911.1 - 0.13 12.7 1.4 21 5.5 0.1 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS82911.1 - 0.14 12.6 0.0 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 RUS82911.1 - 0.15 11.8 3.6 1.2 8.8 0.8 2.7 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 RUS82911.1 - 0.55 10.2 1.7 32 4.5 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4231 PF14015.6 RUS82911.1 - 2.5 8.6 5.1 15 6.1 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Globin PF00042.22 RUS82912.1 - 7.1e-10 39.4 0.0 8.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Globin 7tm_1 PF00001.21 RUS82913.1 - 4.5e-15 55.7 19.4 2.1e-10 40.4 11.6 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82913.1 - 1.9e-11 43.8 30.3 4.8e-11 42.5 30.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw SNF PF00209.18 RUS82915.1 - 3.3e-200 666.2 34.7 6.1e-200 665.3 34.7 1.4 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Macoilin PF09726.9 RUS82916.1 - 0.0018 16.9 15.2 0.0018 16.9 15.2 1.7 2 0 0 2 2 2 1 Macoilin family DUF3361 PF11841.8 RUS82916.1 - 0.058 13.3 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Golgin_A5 PF09787.9 RUS82916.1 - 0.24 10.8 14.3 0.11 12.0 11.4 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 RUS82916.1 - 2.8 8.1 10.7 11 6.2 0.6 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 RUS82916.1 - 3.2 8.0 9.6 0.31 11.2 3.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II UCH PF00443.29 RUS82917.1 - 6.1e-41 140.6 0.3 1.1e-40 139.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS82917.1 - 3.7e-06 26.8 0.0 0.0044 16.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AA_permease_N PF08403.10 RUS82918.1 - 4.1e-09 35.8 0.0 9.6e-09 34.6 0.0 1.6 1 0 0 1 1 1 1 Amino acid permease N-terminal Neogenin_C PF06583.12 RUS82918.1 - 0.0092 15.9 0.2 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 Neogenin C-terminus IPP-2 PF04979.14 RUS82918.1 - 1.1 10.0 7.0 0.16 12.7 3.2 1.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) KH_1 PF00013.29 RUS82919.1 - 3.3e-34 116.5 6.0 4.9e-14 51.9 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RUS82919.1 - 4.9e-10 39.1 2.8 8.5e-05 22.3 0.4 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 RUS82919.1 - 3.2e-08 33.3 0.2 0.0042 16.9 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 RUS82919.1 - 0.00013 22.0 4.7 0.019 15.0 0.6 3.0 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 RUS82919.1 - 0.0035 17.3 0.0 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 KH-like RNA-binding domain RRM_1 PF00076.22 RUS82920.1 - 4.3e-18 64.9 1.0 8.2e-10 38.4 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 RUS82920.1 - 4.4e-11 42.4 1.3 1.4e-10 40.8 0.2 2.3 2 1 0 2 2 2 1 KH domain KH_2 PF07650.17 RUS82920.1 - 4.4e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Smg4_UPF3 PF03467.15 RUS82920.1 - 0.0046 17.0 0.3 0.044 13.8 0.3 2.3 1 1 0 1 1 1 1 Smg-4/UPF3 family KH_4 PF13083.6 RUS82920.1 - 0.0051 16.7 0.1 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 KH domain SET_assoc PF11767.8 RUS82920.1 - 0.011 15.3 0.0 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 RUS82920.1 - 0.013 15.4 0.4 8.3 6.3 0.1 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif KH_5 PF13184.6 RUS82920.1 - 0.014 15.5 0.2 0.041 14.0 0.1 1.9 2 0 0 2 2 2 0 NusA-like KH domain RRM_5 PF13893.6 RUS82920.1 - 0.04 13.5 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PrpR_N PF06506.11 RUS82920.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Propionate catabolism activator RhoGAP PF00620.27 RUS82921.1 - 2.2e-44 151.0 0.1 4.6e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.6 RUS82921.1 - 3.2e-14 53.3 0.1 3.2e-14 53.3 0.1 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 RUS82921.1 - 1.4e-08 35.1 0.2 5.4e-08 33.3 0.2 2.0 1 0 0 1 1 1 1 PH domain Kelch_1 PF01344.25 RUS82922.1 - 2.9e-47 158.0 14.6 3.4e-15 55.3 0.3 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 RUS82922.1 - 3.4e-28 97.0 6.4 4.4e-07 30.0 0.0 5.3 1 1 4 5 5 5 4 Kelch motif BTB PF00651.31 RUS82922.1 - 3.8e-21 75.4 0.0 7.3e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 RUS82922.1 - 2.4e-19 69.0 0.9 4.9e-06 26.5 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain BACK PF07707.15 RUS82922.1 - 3.9e-18 65.5 3.3 3.9e-18 65.4 0.7 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RUS82922.1 - 2.5e-15 56.3 3.0 4.7e-05 23.6 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS82922.1 - 2.6e-14 52.5 4.9 0.001 19.0 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 RUS82922.1 - 4.6e-11 42.5 2.4 0.061 13.3 0.0 4.4 4 0 0 4 4 4 4 Kelch motif 7tm_2 PF00002.24 RUS82924.1 - 3.3e-74 249.3 12.9 4e-74 249.0 12.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 RUS82924.1 - 4.1e-13 49.4 4.2 9.8e-13 48.2 4.2 1.7 1 0 0 1 1 1 1 Hormone receptor domain Transposase_1 PF01359.18 RUS82926.1 - 4e-20 71.4 0.1 6.3e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS82926.1 - 0.00053 19.8 0.1 0.00089 19.0 0.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease CHGN PF05679.16 RUS82928.1 - 1e-113 380.9 4.5 1.6e-113 380.3 4.5 1.3 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Cystatin PF00031.21 RUS82928.1 - 0.053 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Cystatin domain AAA PF00004.29 RUS82929.1 - 3.7e-43 147.1 0.0 7.6e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS82929.1 - 1.9e-12 46.8 0.0 4.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RUS82929.1 - 1.9e-07 30.9 0.4 4.9e-07 29.6 0.4 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 RUS82929.1 - 6.3e-07 29.7 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RUS82929.1 - 7.9e-07 29.2 0.0 2.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS82929.1 - 2.8e-06 27.8 0.1 6.1e-05 23.5 0.1 2.6 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 RUS82929.1 - 9.1e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS82929.1 - 0.00025 21.3 2.5 0.0079 16.5 0.5 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 RUS82929.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RUS82929.1 - 0.0019 17.5 0.0 0.0046 16.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RUS82929.1 - 0.0019 18.7 0.7 0.011 16.3 0.0 2.6 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 RUS82929.1 - 0.002 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RUS82929.1 - 0.0058 16.0 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Filament PF00038.21 RUS82929.1 - 0.0064 16.1 1.5 0.011 15.3 1.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein PhoH PF02562.16 RUS82929.1 - 0.0071 15.8 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 RUS82929.1 - 0.0081 16.0 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 RUS82929.1 - 0.01 15.2 0.3 0.038 13.3 0.0 2.0 2 0 0 2 2 2 0 KaiC RILP PF11461.8 RUS82929.1 - 0.012 15.8 2.2 0.032 14.5 2.2 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein NB-ARC PF00931.22 RUS82929.1 - 0.013 14.7 0.1 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 RUS82929.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RUS82929.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 RUS82929.1 - 0.03 14.1 0.0 0.076 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RUS82929.1 - 0.031 13.8 0.2 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RUS82929.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RUS82929.1 - 0.037 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 RUS82929.1 - 0.04 13.1 0.0 0.096 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RUS82929.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain HAUS-augmin3 PF14932.6 RUS82929.1 - 0.056 13.0 0.6 0.083 12.5 0.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 RNA_helicase PF00910.22 RUS82929.1 - 0.057 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 RUS82929.1 - 0.058 13.2 0.9 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 RUS82929.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SlyX PF04102.12 RUS82929.1 - 0.062 13.9 2.5 0.23 12.1 2.5 2.0 1 0 0 1 1 1 0 SlyX AAA_17 PF13207.6 RUS82929.1 - 0.097 13.1 0.5 0.53 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 RUS82929.1 - 0.11 11.8 0.2 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 RUS82929.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 RUS82929.1 - 0.18 12.3 2.5 0.35 11.4 2.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region NACHT PF05729.12 RUS82929.1 - 0.19 11.6 0.3 0.68 9.8 0.0 2.0 3 0 0 3 3 2 0 NACHT domain MscS_porin PF12795.7 RUS82929.1 - 0.53 9.8 7.7 0.89 9.0 7.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HR1 PF02185.16 RUS82929.1 - 1.2 9.3 7.6 0.75 10.0 4.6 2.2 2 0 0 2 2 2 0 Hr1 repeat SH3_9 PF14604.6 RUS82930.1 - 2.4e-15 56.1 0.3 4.3e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS82930.1 - 2.5e-13 49.4 0.4 5.3e-13 48.4 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS82930.1 - 3.5e-07 29.8 0.0 6.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain OspE PF02471.17 RUS82930.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein E MCM_bind PF09739.9 RUS82930.1 - 0.15 10.5 2.6 0.17 10.3 2.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor An_peroxidase PF03098.15 RUS82931.1 - 8e-146 486.7 0.3 9.4e-145 483.2 0.3 2.6 1 1 0 1 1 1 1 Animal haem peroxidase CENP-B_dimeris PF09026.10 RUS82931.1 - 0.0029 18.0 4.0 0.0085 16.5 4.0 1.8 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RUS82931.1 - 1.5 8.5 5.8 2.7 7.7 5.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 RUS82931.1 - 8.4 6.9 8.5 21 5.6 8.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ANAPC5 PF12862.7 RUS82932.1 - 3e-25 88.1 0.3 3e-25 88.1 0.3 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 RUS82932.1 - 1.1e-05 25.6 16.7 0.0032 17.7 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS82932.1 - 0.0019 18.2 13.9 1.6 9.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS82932.1 - 0.0035 17.4 7.0 11 6.6 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS82932.1 - 0.0067 17.0 8.5 11 6.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CLTH PF10607.9 RUS82932.1 - 0.027 14.4 0.2 0.15 11.9 0.2 2.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TPR_4 PF07721.14 RUS82932.1 - 0.039 14.6 21.8 0.23 12.2 1.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS82932.1 - 0.046 14.5 19.8 13 6.9 0.8 6.8 5 2 2 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 RUS82932.1 - 0.056 13.1 1.7 0.15 11.7 0.3 2.4 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TetR_C_32 PF09209.11 RUS82932.1 - 0.059 13.4 0.1 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_19 PF14559.6 RUS82932.1 - 0.086 13.4 15.4 14 6.3 0.2 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2536 PF10750.9 RUS82932.1 - 0.088 12.7 3.5 0.076 12.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF630 PF04783.12 RUS82932.1 - 0.18 12.0 3.0 16 5.8 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF630) TPR_16 PF13432.6 RUS82932.1 - 0.22 12.2 0.2 0.22 12.2 0.2 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS82932.1 - 1.6 8.7 17.2 2.4 8.1 1.8 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS82932.1 - 4.8 7.2 10.0 17 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ECR1_N PF14382.6 RUS82933.1 - 1.2e-16 60.2 0.4 2.2e-16 59.4 0.4 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 RUS82933.1 - 3.9e-12 46.3 0.0 8.8e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 RUS82933.1 - 0.0091 16.6 0.5 4.7 7.9 0.1 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 zf-C4 PF00105.18 RUS82934.1 - 3.3e-31 107.5 13.6 7.6e-31 106.4 13.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Gal-bind_lectin PF00337.22 RUS82935.1 - 1.9e-12 46.8 0.0 3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 RUS82936.1 - 2e-25 88.9 0.2 4.4e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Galactoside-binding lectin TPR_12 PF13424.6 RUS82937.1 - 0.15 12.4 8.8 5.3 7.4 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat KH_1 PF00013.29 RUS82938.1 - 4.2e-65 215.5 19.7 1.4e-16 60.1 0.7 4.4 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 RUS82938.1 - 3.4e-19 68.4 7.4 0.00039 20.2 0.4 4.5 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 RUS82938.1 - 1.8e-16 59.3 3.3 1.8e-16 59.3 3.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1897) KH_4 PF13083.6 RUS82938.1 - 2.7e-08 33.5 14.6 0.017 15.0 0.7 4.5 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 RUS82938.1 - 0.026 14.6 11.5 14 5.8 0.1 4.6 4 1 0 4 4 4 0 NusA-like KH domain Asp_Arg_Hydrox PF05118.15 RUS82938.1 - 0.16 11.8 1.0 0.27 11.1 1.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase CCDC53 PF10152.9 RUS82938.1 - 4.1 7.8 9.8 1.4 9.3 3.4 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Trypan_PARP PF05887.11 RUS82939.1 - 0.0082 16.1 15.0 0.0082 16.1 15.0 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 RUS82939.1 - 0.038 12.1 3.6 0.043 11.9 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2201_N PF13203.6 RUS82939.1 - 0.19 11.3 6.5 0.2 11.2 6.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF913 PF06025.12 RUS82939.1 - 0.48 9.4 1.4 0.49 9.3 1.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 RUS82939.1 - 0.65 9.8 10.9 0.7 9.7 10.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 RUS82939.1 - 1.1 9.0 9.2 1.1 9.0 9.2 1.1 1 0 0 1 1 1 0 AAA domain PRP38_assoc PF12871.7 RUS82939.1 - 1.6 9.4 57.7 10 6.8 57.7 1.9 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RNA_pol_Rpc4 PF05132.14 RUS82939.1 - 1.8 9.0 4.7 2.3 8.6 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 VIR_N PF15912.5 RUS82939.1 - 2.3 7.8 14.0 3 7.4 14.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Paf1 PF03985.13 RUS82939.1 - 9.5 5.1 20.4 11 4.9 20.4 1.1 1 0 0 1 1 1 0 Paf1 Abhydrolase_1 PF00561.20 RUS82940.1 - 4.4e-42 144.5 0.0 6.2e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 RUS82940.1 - 0.0016 18.1 0.1 0.0028 17.4 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 RUS82940.1 - 0.0084 15.4 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS82940.1 - 0.016 15.8 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 RUS82940.1 - 0.095 12.5 0.0 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RUS82940.1 - 0.099 12.1 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 RUS82940.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Sporozoite_P67 PF05642.11 RUS82941.1 - 0.0005 18.3 14.7 0.0005 18.3 14.7 3.1 1 1 1 3 3 1 1 Sporozoite P67 surface antigen DUF2457 PF10446.9 RUS82941.1 - 0.00082 18.6 23.3 0.00082 18.6 23.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS82941.1 - 0.0025 16.0 77.5 0.078 11.1 29.9 2.1 2 0 0 2 2 2 2 DNA polymerase phi CENP-B_dimeris PF09026.10 RUS82941.1 - 0.0045 17.3 21.5 0.0045 17.3 21.5 3.9 2 1 0 2 2 1 1 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 RUS82941.1 - 0.0085 15.9 14.6 0.0085 15.9 14.6 2.9 2 1 0 2 2 1 1 Pox virus Ag35 surface protein Ribosomal_60s PF00428.19 RUS82941.1 - 0.015 15.9 9.4 0.015 15.9 9.4 5.2 3 1 0 3 3 2 0 60s Acidic ribosomal protein Tim54 PF11711.8 RUS82941.1 - 0.1 11.4 35.5 0.14 10.9 17.7 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 RUS82941.1 - 0.12 10.6 71.5 0.014 13.6 19.6 2.0 2 0 0 2 2 2 0 Nop14-like family Mucin PF01456.17 RUS82941.1 - 0.14 12.1 10.4 0.26 11.3 10.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BUD22 PF09073.10 RUS82941.1 - 0.37 10.1 58.4 0.015 14.7 13.4 2.1 2 0 0 2 2 2 0 BUD22 Mpp10 PF04006.12 RUS82941.1 - 0.4 9.1 73.2 0.044 12.2 20.0 2.0 2 0 0 2 2 2 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 RUS82941.1 - 0.44 11.0 27.1 1 9.8 13.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS82941.1 - 6.2 5.5 33.2 1.8 7.2 5.6 2.1 2 0 0 2 2 2 0 Presenilin DUF5523 PF17661.1 RUS82941.1 - 8.6 6.0 62.2 0.24 11.0 15.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) BTB PF00651.31 RUS82942.1 - 6.8e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS82943.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Kelch_1 PF01344.25 RUS82944.1 - 2.8e-79 260.5 17.3 3.3e-16 58.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS82944.1 - 1.1e-47 158.8 3.5 5.5e-09 36.0 0.1 6.2 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RUS82944.1 - 1.4e-28 97.8 15.3 5.1e-05 23.1 0.1 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RUS82944.1 - 1.5e-23 82.5 4.9 3.8e-06 26.8 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS82944.1 - 5.6e-19 67.9 8.8 0.00063 20.0 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS82944.1 - 7.8e-14 51.3 3.6 0.074 13.1 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Glyoxal_oxid_N PF07250.11 RUS82944.1 - 1.2e-05 24.7 1.9 0.023 13.9 0.1 2.2 1 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1668 PF07893.13 RUS82944.1 - 0.0023 17.4 0.0 2.4 7.4 0.0 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF1668) FliO PF04347.13 RUS82944.1 - 0.09 13.1 2.3 21 5.5 0.0 3.7 3 1 1 4 4 4 0 Flagellar biosynthesis protein, FliO PLDc PF00614.22 RUS82944.1 - 0.093 12.9 4.5 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif PQQ_3 PF13570.6 RUS82944.1 - 2.3 8.8 17.5 14 6.3 1.5 5.9 6 1 0 7 7 6 0 PQQ-like domain NAP PF00956.18 RUS82946.1 - 2.1e-40 138.6 14.2 8.7e-35 120.2 6.2 3.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 RUS82946.1 - 0.025 14.5 2.5 0.025 14.5 2.5 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 RUS82946.1 - 0.046 13.1 1.5 0.069 12.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.6 RUS82946.1 - 0.12 12.5 2.8 0.3 11.2 2.8 1.7 1 0 0 1 1 1 0 Up-regulated During Septation DUF1492 PF07374.11 RUS82946.1 - 0.19 11.9 2.2 0.41 10.8 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) DUF148 PF02520.17 RUS82946.1 - 2 8.6 10.2 0.13 12.4 4.6 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Bactofilin PF04519.13 RUS82948.1 - 6.7e-05 23.1 0.0 0.016 15.5 0.0 2.4 1 1 1 2 2 2 2 Polymer-forming cytoskeletal DUF4447 PF14590.6 RUS82948.1 - 0.0024 17.7 6.9 9.4 6.0 0.1 4.5 1 1 5 6 6 6 5 Domain of unknown function (DUF4447) Phage_head_chap PF11113.8 RUS82948.1 - 0.13 12.4 7.7 1.8e+02 2.3 0.0 5.4 7 0 0 7 7 7 0 Head assembly gene product Glyco_trans_4_5 PF16994.5 RUS82948.1 - 7.3 6.2 19.2 12 5.5 0.2 5.7 2 1 5 7 7 7 0 Glycosyl-transferase family 4 Ank_2 PF12796.7 RUS82949.1 - 4.3e-88 290.0 21.8 1.3e-18 67.4 0.2 7.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS82949.1 - 2e-76 242.7 23.5 8.4e-05 22.7 0.1 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.6 RUS82949.1 - 1e-75 249.2 21.6 5.5e-10 39.6 0.1 11.6 2 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS82949.1 - 6.9e-70 230.2 30.2 3.2e-09 36.8 0.0 11.6 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 RUS82949.1 - 5.3e-69 225.9 35.8 2.9e-06 27.5 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat DUF249 PF03158.13 RUS82949.1 - 1.7e-05 24.6 0.8 0.36 10.5 0.1 5.4 2 2 2 6 6 6 1 Multigene family 530 protein DCB PF16213.5 RUS82949.1 - 0.0068 16.1 0.1 2.9 7.5 0.0 4.1 4 2 1 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 YfmQ PF10787.9 RUS82949.1 - 0.054 13.3 0.0 2.9 7.6 0.0 3.3 2 2 1 3 3 3 0 Uncharacterised protein from bacillus cereus group CHAP PF05257.16 RUS82949.1 - 0.061 13.9 2.7 7.2 7.3 0.1 4.0 4 0 0 4 4 4 0 CHAP domain AMOP PF03782.17 RUS82951.1 - 2.3e-35 121.8 5.2 2e-19 70.1 1.6 2.3 2 0 0 2 2 2 2 AMOP domain VWD PF00094.25 RUS82951.1 - 7.3e-13 49.1 0.0 7.2e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain Sushi PF00084.20 RUS82951.1 - 2.5e-09 37.6 0.7 7.4e-09 36.1 0.7 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) EphA2_TM PF14575.6 RUS82951.1 - 0.073 14.0 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIO1 PF01163.22 RUS82952.1 - 0.09 12.4 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family GDPD PF03009.17 RUS82953.1 - 2e-59 201.4 0.1 3.3e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 RUS82953.1 - 6.6e-13 48.4 0.0 1.9e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain TMEM141 PF15110.6 RUS82954.1 - 1.8e-20 73.3 0.4 2.3e-20 73.0 0.4 1.1 1 0 0 1 1 1 1 TMEM141 protein family VWA PF00092.28 RUS82956.1 - 6.3e-80 267.5 3.5 3.4e-36 125.1 0.0 3.3 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS82956.1 - 5.4e-35 120.3 0.1 4.1e-15 56.3 0.1 3.6 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 RUS82956.1 - 3.8e-18 65.9 0.8 1.3e-06 28.5 0.0 3.8 3 1 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS82956.1 - 5.5e-08 32.5 2.5 0.0058 16.0 0.0 2.9 3 0 0 3 3 3 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 RUS82956.1 - 5.4e-06 26.7 0.5 0.00013 22.1 0.2 2.4 2 0 0 2 2 2 1 vWA found in TerF C terminus Copine PF07002.16 RUS82956.1 - 0.00021 20.8 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 Copine TmoB PF06234.12 RUS82956.1 - 0.006 16.6 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) Rad60-SLD PF11976.8 RUS82956.1 - 0.032 14.0 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PS_pyruv_trans PF04230.13 RUS82956.1 - 0.14 12.1 0.0 6.5 6.6 0.0 2.7 2 1 1 3 3 3 0 Polysaccharide pyruvyl transferase RNA_pol_Rpb2_6 PF00562.28 RUS82957.1 - 2.4e-127 425.2 0.1 3.4e-127 424.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RUS82957.1 - 4.5e-67 225.5 0.0 6.2e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 RUS82957.1 - 5.8e-55 185.9 0.1 1.4e-54 184.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 RUS82957.1 - 2e-34 117.8 0.6 4.1e-34 116.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RUS82957.1 - 2.1e-24 85.5 0.1 1.1e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RUS82957.1 - 1.2e-21 76.7 1.5 1.8e-21 76.2 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 RUS82957.1 - 1.2e-16 60.9 0.0 2.9e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.8 RUS82957.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme C1_2 PF03107.16 RUS82957.1 - 0.79 10.1 2.5 3.3 8.1 2.5 2.0 1 1 0 1 1 1 0 C1 domain TSP_1 PF00090.19 RUS82958.1 - 1.4e-07 31.6 10.2 1.4e-07 31.6 10.2 5.0 4 3 0 4 4 4 1 Thrombospondin type 1 domain VWC PF00093.18 RUS82958.1 - 8.4e-05 22.8 1.7 8.4e-05 22.8 1.7 6.4 4 3 2 6 6 6 1 von Willebrand factor type C domain TIL PF01826.17 RUS82958.1 - 8.7e-05 22.7 7.5 8.7e-05 22.7 7.5 7.6 2 1 3 6 6 6 1 Trypsin Inhibitor like cysteine rich domain Ldl_recept_a PF00057.18 RUS82959.1 - 3.7e-26 91.0 70.8 4.2e-10 39.7 14.5 9.5 9 0 0 9 9 9 4 Low-density lipoprotein receptor domain class A VWD PF00094.25 RUS82959.1 - 6.1e-11 42.8 0.0 1.6e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type D domain TIL PF01826.17 RUS82959.1 - 3.8e-08 33.5 13.1 3.8e-08 33.5 13.1 11.5 7 4 0 7 7 7 2 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 RUS82961.1 - 1.1e-24 87.5 9.9 5.5e-13 49.5 2.9 2.3 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 RUS82961.1 - 1.7e-10 41.2 4.2 1.7e-10 41.2 4.2 2.9 2 0 0 2 2 2 1 C8 domain Cmc1 PF08583.10 RUS82961.1 - 0.0017 18.4 0.5 0.005 16.8 0.5 1.8 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1655 PF07868.11 RUS82961.1 - 0.15 12.1 0.0 0.62 10.2 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) DUF559 PF04480.12 RUS82961.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF559) BRICHOS PF04089.14 RUS82962.1 - 0.0052 17.0 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 BRICHOS domain Presenilin PF01080.17 RUS82962.1 - 1.2 7.8 4.7 4.2 6.0 2.8 2.0 2 0 0 2 2 2 0 Presenilin DNA_pol_phi PF04931.13 RUS82962.1 - 1.9 6.5 12.1 2.6 6.1 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 RUS82962.1 - 9.2 5.9 16.2 14 5.3 16.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_C2 PF00648.21 RUS82963.1 - 3.8e-43 147.6 0.3 1.9e-42 145.3 0.0 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 RUS82963.1 - 7.1e-23 80.4 11.9 9.3e-12 44.8 3.3 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 RUS82963.1 - 3.8e-17 62.9 0.1 1.8e-10 41.3 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III TPR_1 PF00515.28 RUS82963.1 - 7.5e-05 22.4 2.1 0.33 10.8 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS82963.1 - 0.00017 21.5 3.1 1.1 9.5 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS82963.1 - 0.0039 16.8 3.2 0.17 11.6 0.1 3.2 3 0 0 3 3 3 1 TPR repeat Aida_N PF08910.10 RUS82963.1 - 0.34 11.3 1.3 0.97 9.9 0.1 2.3 3 0 0 3 3 3 0 Aida N-terminus TPR_8 PF13181.6 RUS82963.1 - 0.83 10.0 6.5 5.2 7.5 0.1 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 RUS82963.1 - 2.1 7.7 7.3 1.1 8.6 0.9 2.3 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RUS82963.1 - 2.4 8.5 5.7 4.7 7.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3678 PF12435.8 RUS82964.1 - 0.013 14.9 0.8 0.03 13.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) CheC PF04509.12 RUS82965.1 - 0.017 15.0 0.8 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 CheC-like family DUF4249 PF14054.6 RUS82965.1 - 0.028 14.1 0.0 0.13 11.8 0.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4249) fn3 PF00041.21 RUS82966.1 - 1.1e-06 28.9 12.2 1.5 9.3 0.0 8.5 7 0 0 7 7 7 3 Fibronectin type III domain PAN_1 PF00024.26 RUS82966.1 - 1.1e-05 25.3 0.1 4.5e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 PAN domain Meleagrin PF08189.11 RUS82966.1 - 4.2 7.2 7.5 21 4.9 0.9 2.7 2 0 0 2 2 2 0 Meleagrin/Cygnin family SAP PF02037.27 RUS82967.1 - 5e-20 70.8 0.5 1.5e-06 27.8 0.0 4.0 3 0 0 3 3 3 3 SAP domain Peptidase_M23 PF01551.22 RUS82967.1 - 0.00046 20.4 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M23 Coatomer_g_Cpla PF16381.5 RUS82967.1 - 0.02 15.0 0.2 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform rpo30_N PF12410.8 RUS82967.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit SbsC_C PF18058.1 RUS82967.1 - 0.16 12.2 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 SbsC C-terminal domain Vitellogenin_N PF01347.22 RUS82967.1 - 0.17 10.3 0.5 8.3 4.7 0.0 2.9 3 0 0 3 3 3 0 Lipoprotein amino terminal region Cdc13_OB4_dimer PF18233.1 RUS82969.1 - 0.0092 16.1 0.7 0.54 10.4 0.0 2.7 2 2 1 3 3 3 1 Cdc13 OB4 dimerization domain DUF4014 PF13198.6 RUS82969.1 - 0.32 11.4 5.8 81 3.7 0.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF4014) NDT80_PhoG PF05224.12 RUS82969.1 - 0.35 11.1 8.9 3.7 7.7 0.2 3.8 1 1 3 4 4 4 0 NDT80 / PhoG like DNA-binding family Alk_phosphatase PF00245.20 RUS82971.1 - 1.6e-125 419.4 1.0 1.8e-123 412.6 1.0 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS82971.1 - 0.025 14.0 0.0 0.031 13.6 0.0 1.4 1 1 0 1 1 1 0 Metalloenzyme superfamily DUF2481 PF10654.9 RUS82972.1 - 0.058 13.4 0.2 0.084 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) KELK PF15796.5 RUS82972.1 - 0.099 13.1 2.4 0.17 12.3 2.4 1.3 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF533 PF04391.12 RUS82972.1 - 1.2 8.7 8.6 1.3 8.6 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) MIEAP PF16026.5 RUS82974.1 - 0.72 10.0 6.2 1.4 9.1 6.2 1.4 1 0 0 1 1 1 0 Mitochondria-eating protein Fib_alpha PF08702.10 RUS82974.1 - 2.3 8.4 11.8 15 5.8 0.3 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 RUS82974.1 - 6.9 4.5 17.3 2.4 6.0 13.3 2.0 1 1 1 2 2 2 0 Prominin COesterase PF00135.28 RUS82975.1 - 3.5e-40 138.3 0.0 4.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS82975.1 - 0.00019 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS82975.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 RUS82976.1 - 5.7e-16 58.5 0.2 6.3e-16 58.3 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF1796 PF08795.10 RUS82977.1 - 9.2 6.2 8.6 1.4 8.9 1.3 2.9 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DUF1639 PF07797.14 RUS82978.1 - 3.7e-06 26.8 0.0 47 4.1 0.0 6.0 3 2 5 8 8 8 0 Protein of unknown function (DUF1639) Receptor_IA-2 PF11548.8 RUS82978.1 - 0.013 15.4 0.5 45 4.1 0.0 4.1 1 1 4 5 5 5 0 Protein-tyrosine phosphatase receptor IA-2 DUF4973 PF16343.5 RUS82978.1 - 0.044 13.8 0.1 14 5.7 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4973) CBM_X2 PF03442.14 RUS82978.1 - 0.085 13.0 0.0 56 3.9 0.0 3.6 1 1 3 4 4 4 0 Carbohydrate binding domain X2 CHDNT PF08073.12 RUS82979.1 - 5.3e-13 48.7 0.2 8e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YL1 PF05764.13 RUS82979.1 - 0.2 11.7 20.5 0.27 11.3 20.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AP3D1 PF06375.11 RUS82979.1 - 0.79 10.0 23.6 0.26 11.5 20.9 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 TFIIF_alpha PF05793.12 RUS82979.1 - 1.3 7.5 25.4 1.5 7.3 25.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIIAH PF12685.7 RUS82979.1 - 3.4 7.5 10.4 4.3 7.1 10.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 RUS82979.1 - 3.6 5.8 15.6 3.5 5.8 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RUS82979.1 - 4.6 5.9 11.0 5.2 5.7 11.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 RUS82979.1 - 7.1 5.1 10.1 9.6 4.6 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FancD2 PF14631.6 RUS82979.1 - 8.3 3.7 8.1 7.9 3.7 8.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peptidase_S49_N PF08496.10 RUS82979.1 - 9.3 6.3 8.5 14 5.8 8.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Acyl-ACP_TE PF01643.17 RUS82980.1 - 7.1e-12 45.1 0.0 1.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS82980.1 - 0.0056 17.2 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 Thioesterase-like superfamily Acatn PF13000.7 RUS82982.1 - 6.9e-113 378.0 17.6 6.3e-72 242.8 8.1 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 HIT PF01230.23 RUS82983.1 - 3.8e-25 88.5 0.1 5e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RUS82983.1 - 2e-05 25.0 0.0 2.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 RUS82983.1 - 0.077 12.7 0.1 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CN_hydrolase PF00795.22 RUS82984.1 - 1.2e-51 175.6 0.0 1.5e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GWT1 PF06423.12 RUS82985.1 - 0.003 17.7 0.8 16 5.6 0.2 3.9 3 1 0 3 3 3 2 GWT1 Peptidase_M14 PF00246.24 RUS82986.1 - 2.5e-35 122.7 0.0 2.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Calpain_III PF01067.22 RUS82986.1 - 0.0021 18.3 0.1 2.9 8.1 0.0 2.6 1 1 1 2 2 2 2 Calpain large subunit, domain III DUF4038 PF13204.6 RUS82986.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Rad9_Rad53_bind PF08605.10 RUS82987.1 - 0.069 13.3 0.0 12 6.0 0.0 2.2 1 1 1 2 2 2 0 Fungal Rad9-like Rad53-binding L27 PF02828.16 RUS82989.1 - 2e-20 72.3 0.4 5.2e-20 70.9 0.1 1.8 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 RUS82989.1 - 2.7e-19 69.3 0.2 4e-19 68.8 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS82989.1 - 4.2e-11 42.5 0.2 1.3e-10 40.9 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS82989.1 - 0.01 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain LIM PF00412.22 RUS82990.1 - 4.8e-28 97.2 23.8 5.8e-15 55.3 8.4 2.2 2 0 0 2 2 2 2 LIM domain PHD_4 PF16866.5 RUS82990.1 - 0.026 14.6 2.3 0.026 14.6 2.3 2.5 2 0 0 2 2 2 0 PHD-finger AGTRAP PF06396.11 RUS82992.1 - 3.6e-26 91.7 4.3 8e-26 90.6 4.3 1.6 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) AGTRAP PF06396.11 RUS82993.1 - 1.8e-29 102.5 0.2 2.1e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF1713 PF08213.11 RUS82994.1 - 2.7e-08 33.6 24.0 5.2e-08 32.7 24.0 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) 7tm_1 PF00001.21 RUS82995.1 - 2.3e-09 37.0 9.6 1.3e-06 27.9 0.8 2.6 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) SUIM_assoc PF16619.5 RUS82995.1 - 3.1 7.9 5.0 1.1 9.4 1.5 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 7tm_1 PF00001.21 RUS82996.1 - 1.1e-08 34.8 15.8 1.4e-08 34.4 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS82996.1 - 0.00074 18.9 17.1 0.031 13.6 17.1 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw adh_short PF00106.25 RUS82997.1 - 1.2e-22 80.3 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS82997.1 - 8.2e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS82997.1 - 4.3e-09 36.5 0.0 6.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 RUS82997.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RNase_H PF00075.24 RUS82998.1 - 1.2e-13 51.5 2.3 2.7e-13 50.3 0.2 2.4 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS82998.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like E1_DerP2_DerF2 PF02221.15 RUS82999.1 - 5.4e-07 30.1 0.1 8.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 ML domain EPTP PF03736.17 RUS83000.1 - 0.0032 17.4 0.0 1.4e+02 2.5 0.0 5.4 2 2 5 7 7 7 0 EPTP domain BDV_G PF06208.11 RUS83000.1 - 0.0042 16.3 0.1 4.2 6.4 0.0 3.1 1 1 3 4 4 4 3 Borna disease virus G protein Gln-synt_N_2 PF16952.5 RUS83000.1 - 0.01 15.7 1.3 66 3.4 0.0 4.4 1 1 2 4 4 4 0 Glutamine synthetase N-terminal domain PurL_C PF16904.5 RUS83000.1 - 0.04 14.2 0.9 88 3.5 0.0 3.7 1 1 3 4 4 4 0 Phosphoribosylformylglycinamidine synthase II C-terminus PH PF00169.29 RUS83001.1 - 6e-09 36.4 0.3 0.018 15.6 0.0 3.2 2 1 1 3 3 3 3 PH domain BTK PF00779.19 RUS83001.1 - 2.1e-06 27.4 0.1 4.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 BTK motif DUF684 PF05075.14 RUS83001.1 - 0.088 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF684) GLTT PF01744.20 RUS83006.1 - 0.22 11.3 0.1 2.4 8.0 0.1 2.7 1 1 0 1 1 1 0 GLTT repeat (6 copies) AhpC-TSA PF00578.21 RUS83010.1 - 5.3e-36 123.3 0.0 1.4e-35 121.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 RUS83010.1 - 2e-14 53.5 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RUS83010.1 - 6.7e-14 51.5 0.1 1.3e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF4207 PF13904.6 RUS83011.1 - 4.4e-06 26.6 71.1 3.9e-05 23.5 44.2 4.1 2 2 1 3 3 3 2 Domain of unknown function (DUF4207) Lipase_3 PF01764.25 RUS83012.1 - 6.3e-14 52.0 0.0 1.4e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RUS83012.1 - 0.013 16.1 0.0 0.037 14.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2749 PF10907.8 RUS83012.1 - 0.25 11.5 1.4 30 4.9 0.8 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Frag1 PF10277.9 RUS83012.1 - 0.53 9.8 5.0 0.95 9.0 5.0 1.3 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family SWIRM PF04433.17 RUS83013.1 - 1.7e-20 73.1 0.0 4.7e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 RUS83013.1 - 3.2e-11 43.2 0.0 6.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RUS83013.1 - 6.6e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RUS83013.1 - 0.00013 22.2 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fn_bind PF02986.14 RUS83013.1 - 0.037 13.7 0.2 0.15 11.8 0.2 2.1 1 0 0 1 1 1 0 Fibronectin binding repeat HECT PF00632.25 RUS83014.1 - 6.9e-50 170.3 0.0 1.2e-49 169.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 RUS83014.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 RUS83014.1 - 0.005 17.0 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain HTH_7 PF02796.15 RUS83014.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Ank_4 PF13637.6 RUS83016.1 - 8.8e-18 64.4 0.5 1.1e-13 51.3 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS83016.1 - 1.3e-15 57.7 0.0 2.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS83016.1 - 1.6e-14 52.5 0.3 4.9e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS83016.1 - 1e-13 51.0 0.0 1.3e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RUS83016.1 - 1.1e-13 51.1 0.1 5.7e-09 36.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 RUS83016.1 - 1.3e-12 47.1 2.1 1.6e-12 46.8 0.4 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RUS83016.1 - 1e-10 41.1 0.0 2.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS83016.1 - 1.6e-10 40.7 0.1 3.9e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1843 PF08898.10 RUS83016.1 - 0.0074 16.8 5.5 0.87 10.1 0.1 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1843) AAA PF00004.29 RUS83017.1 - 8.7e-43 145.9 0.0 1.9e-42 144.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS83017.1 - 3.4e-10 39.6 0.8 7.6e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RUS83017.1 - 1.8e-08 34.2 0.7 3.7e-08 33.2 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 RUS83017.1 - 2.5e-07 31.2 0.2 0.00022 21.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RUS83017.1 - 2.3e-06 27.7 0.1 5.7e-05 23.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS83017.1 - 2.4e-05 24.2 0.0 5.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS83017.1 - 2.8e-05 24.3 0.0 0.00025 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RUS83017.1 - 5.4e-05 23.5 0.5 0.003 17.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RUS83017.1 - 0.0029 18.1 0.1 0.023 15.2 0.0 2.4 2 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 RUS83017.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 RUS83017.1 - 0.0038 16.8 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Prot_ATP_OB_N PF17758.1 RUS83017.1 - 0.0039 16.8 0.1 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 RUS83017.1 - 0.0065 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 RUS83017.1 - 0.0069 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 RUS83017.1 - 0.0074 16.2 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RUS83017.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RUS83017.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 RUS83017.1 - 0.018 14.8 0.3 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 RUS83017.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 RUS83017.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RUS83017.1 - 0.024 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase GAS PF13851.6 RUS83017.1 - 0.024 14.0 4.2 0.043 13.2 4.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_24 PF13479.6 RUS83017.1 - 0.027 14.2 0.0 0.079 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RUS83017.1 - 0.029 14.1 0.2 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Occludin_ELL PF07303.13 RUS83017.1 - 0.037 14.8 0.3 0.082 13.6 0.3 1.5 1 0 0 1 1 1 0 Occludin homology domain AAA_25 PF13481.6 RUS83017.1 - 0.054 13.1 0.2 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS83017.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 RUS83017.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RUS83017.1 - 0.13 11.6 0.2 0.68 9.2 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 RUS83017.1 - 0.17 11.5 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain CENP-Q PF13094.6 RUS83017.1 - 0.3 11.3 5.5 0.8 9.9 5.0 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_23 PF13476.6 RUS83017.1 - 0.49 10.9 3.9 67 3.9 5.1 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 RUS83018.1 - 1.2e-16 60.6 9.7 1.2e-16 60.6 9.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS83018.1 - 0.0096 14.5 24.4 0.0076 14.8 2.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein SAPS PF04499.15 RUS83019.1 - 0.041 12.7 4.2 0.044 12.6 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1_like PF12832.7 RUS83019.1 - 0.21 10.4 3.3 0.28 10.0 3.3 1.2 1 0 0 1 1 1 0 MFS_1 like family CobT PF06213.12 RUS83019.1 - 0.28 10.5 25.7 0.38 10.1 25.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 RUS83019.1 - 0.9 8.9 38.3 1.2 8.5 38.3 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS83019.1 - 3 6.0 40.9 3.7 5.6 40.9 1.0 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 RUS83020.1 - 1.9e-14 53.4 18.3 6.9e-14 51.5 18.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PhoLip_ATPase_C PF16212.5 RUS83020.1 - 0.0054 16.5 11.2 0.038 13.7 7.6 2.2 2 0 0 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal MFS_2 PF13347.6 RUS83020.1 - 0.46 9.0 14.5 0.097 11.2 3.5 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein MFS_1 PF07690.16 RUS83021.1 - 4.2e-19 68.7 7.9 4.2e-19 68.7 7.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS83021.1 - 0.00017 20.3 9.9 0.00032 19.4 0.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PhoLip_ATPase_C PF16212.5 RUS83021.1 - 0.0016 18.2 3.0 0.0016 18.2 3.0 2.4 3 0 0 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal S-antigen PF05756.11 RUS83021.1 - 0.12 12.7 0.2 0.28 11.6 0.2 1.5 1 0 0 1 1 1 0 S-antigen protein UXS1_N PF11803.8 RUS83021.1 - 0.35 11.3 0.9 1.6 9.1 0.0 2.4 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal MFS_1 PF07690.16 RUS83022.1 - 1.9e-10 40.2 6.6 1.9e-10 40.2 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4305 PF14146.6 RUS83022.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) S-antigen PF05756.11 RUS83022.1 - 0.052 13.9 0.3 0.094 13.1 0.3 1.3 1 0 0 1 1 1 0 S-antigen protein UXS1_N PF11803.8 RUS83022.1 - 0.14 12.5 0.4 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal zf-C2HC_2 PF13913.6 RUS83024.1 - 3.1e-18 65.2 8.1 3.1e-09 36.5 1.3 2.7 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 RUS83024.1 - 0.0037 18.0 4.2 0.95 10.5 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS83024.1 - 0.0048 17.3 2.7 3.1 8.4 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf_UBZ PF18439.1 RUS83024.1 - 0.016 14.8 1.5 4.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RING_7 PF02591.15 RUS83024.1 - 0.1 12.8 0.7 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_11 PF16622.5 RUS83024.1 - 0.23 11.3 1.4 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DNA_mis_repair PF01119.19 RUS83025.1 - 4.5e-12 45.7 0.0 1.7e-09 37.4 0.0 2.6 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 RUS83025.1 - 1.4e-11 44.4 0.5 7.5e-06 25.8 0.0 4.0 1 1 1 2 2 2 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 RUS83025.1 - 3.6e-09 36.6 0.1 9.7e-08 31.9 0.0 3.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS83025.1 - 4.6e-06 27.1 0.0 2.8e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 RUS83028.1 - 8.5e-95 316.9 0.0 1.4e-94 316.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS83028.1 - 4.4e-43 147.5 0.0 1.6e-42 145.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain MLANA PF14991.6 RUS83028.1 - 0.0041 17.4 0.0 0.025 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein melan-A Haspin_kinase PF12330.8 RUS83028.1 - 0.006 15.6 0.0 0.006 15.6 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain fn3 PF00041.21 RUS83028.1 - 0.023 15.0 1.7 1 9.7 0.7 3.2 3 0 0 3 3 3 0 Fibronectin type III domain Pkinase_fungal PF17667.1 RUS83028.1 - 0.03 13.1 0.1 0.059 12.1 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RUS83028.1 - 0.062 13.2 0.0 0.71 9.7 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 RUS83028.1 - 0.096 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family DUF4293 PF14126.6 RUS83028.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Rdx PF10262.9 RUS83033.1 - 6.4e-12 45.5 0.0 1.3e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Rdx family RRM_1 PF00076.22 RUS83035.1 - 1.9e-10 40.4 0.3 5.6e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD2 PF18782.1 RUS83035.1 - 0.0025 18.0 0.5 0.0054 16.8 0.5 1.5 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 Nup35_RRM_2 PF14605.6 RUS83035.1 - 0.0043 17.0 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif APOBEC_C PF05240.14 RUS83035.1 - 0.0059 16.5 1.8 0.02 14.8 1.8 1.8 1 0 0 1 1 1 1 APOBEC-like C-terminal domain APOBEC2 PF18772.1 RUS83035.1 - 0.033 14.2 0.9 0.09 12.8 0.9 1.7 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 RUS83035.1 - 0.1 12.7 0.5 0.18 11.9 0.5 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 DNA_pol_lambd_f PF10391.9 RUS83035.1 - 0.16 11.8 0.1 0.56 10.1 0.1 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda UCH_1 PF13423.6 RUS83035.1 - 0.19 11.3 5.5 0.052 13.1 2.4 1.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Rsa3 PF14615.6 RUS83035.1 - 0.28 10.8 0.9 1 9.0 0.0 2.2 3 0 0 3 3 3 0 Ribosome-assembly protein 3 TMF_DNA_bd PF12329.8 RUS83035.1 - 2.3 8.3 11.6 1.1 9.3 8.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 RUS83035.1 - 3.4 7.7 23.1 0.089 12.9 13.3 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FYTT PF07078.11 RUS83036.1 - 1.5e-06 27.8 4.9 1.5e-06 27.8 4.9 2.5 1 1 1 2 2 2 1 Forty-two-three protein PIEZO PF15917.5 RUS83036.1 - 0.16 11.4 3.2 0.32 10.4 3.2 1.4 1 0 0 1 1 1 0 Piezo DUF3619 PF12279.8 RUS83036.1 - 0.26 11.6 2.6 0.5 10.7 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) EMC3_TMCO1 PF01956.16 RUS83036.1 - 0.29 10.9 2.1 0.46 10.2 2.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SYCE1 PF15233.6 RUS83037.1 - 0.00037 20.6 22.6 0.00037 20.6 22.6 2.3 1 1 1 2 2 2 1 Synaptonemal complex central element protein 1 Fib_alpha PF08702.10 RUS83037.1 - 0.5 10.5 19.5 0.27 11.4 10.7 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PapC_N PF13954.6 RUS83037.1 - 0.65 10.0 5.1 0.35 10.9 1.5 2.2 1 1 2 3 3 3 0 PapC N-terminal domain DUF724 PF05266.14 RUS83037.1 - 1 9.1 31.0 0.034 14.0 12.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) ERM PF00769.19 RUS83037.1 - 1.3 8.8 39.5 3.2 7.5 19.3 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fez1 PF06818.15 RUS83037.1 - 1.5 9.2 30.5 1.2 9.6 14.9 2.1 1 1 0 2 2 2 0 Fez1 EGF_CA PF07645.15 RUS83038.1 - 4.1e-17 62.1 40.9 2.4e-08 34.0 7.0 11.7 12 0 0 12 12 12 3 Calcium-binding EGF domain VWD PF00094.25 RUS83038.1 - 1.8e-15 57.5 0.3 4.6e-15 56.2 0.3 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 RUS83038.1 - 1.9e-12 47.4 1.9 1.9e-12 47.4 1.9 6.5 4 1 2 6 6 6 1 C8 domain TIL PF01826.17 RUS83038.1 - 4.2e-08 33.3 19.8 2.6e-06 27.6 10.4 13.4 10 2 3 13 13 13 2 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 RUS83038.1 - 0.00066 19.5 0.5 0.00066 19.5 0.5 11.8 12 2 1 13 13 13 4 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS83038.1 - 0.013 15.7 0.6 0.013 15.7 0.6 13.2 15 0 0 15 15 15 0 EGF domain Steroid_dh PF02544.16 RUS83040.1 - 2.4e-56 189.9 0.9 2.8e-56 189.7 0.9 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 RUS83040.1 - 9.5e-06 25.3 0.1 1.2e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Archaeal_AmoA PF12942.7 RUS83040.1 - 0.014 15.1 0.1 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) LURAP PF14854.6 RUS83041.1 - 1.9e-09 37.5 3.1 5e-09 36.1 3.1 1.7 1 1 0 1 1 1 1 Leucine rich adaptor protein WASH-7_N PF14745.6 RUS83041.1 - 0.041 12.4 0.0 0.052 12.0 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal TMF_DNA_bd PF12329.8 RUS83041.1 - 0.15 12.1 2.8 0.2 11.7 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HECT PF00632.25 RUS83042.1 - 2.6e-74 250.5 0.1 4.8e-74 249.6 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 RUS83042.1 - 1.1e-05 26.2 0.3 0.00056 20.7 0.0 2.7 2 1 0 2 2 2 1 Filamin/ABP280 repeat CFIA_Pcf11 PF11526.8 RUS83043.1 - 0.0079 16.7 2.1 10 6.7 2.1 4.2 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Asp_decarbox PF02261.16 RUS83043.1 - 0.04 13.9 2.4 12 5.8 0.1 3.1 1 1 1 3 3 3 0 Aspartate decarboxylase adh_short PF00106.25 RUS83044.1 - 5e-44 150.1 0.0 6.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS83044.1 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS83044.1 - 4.5e-09 36.5 0.0 6.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 RUS83044.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 RUS83044.1 - 0.056 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 RUS83044.1 - 0.12 11.6 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acyltransferase PF01553.21 RUS83045.1 - 8.6e-19 67.5 0.0 2.8e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Rrp15p PF07890.12 RUS83047.1 - 1.3e-19 70.9 2.5 1.3e-19 70.9 2.5 1.9 2 0 0 2 2 2 1 Rrp15p PRTP PF01366.18 RUS83047.1 - 0.93 7.5 2.7 1.9 6.4 2.7 1.6 1 1 0 1 1 1 0 Herpesvirus processing and transport protein BACK PF07707.15 RUS83048.1 - 8.7e-31 106.1 0.9 2.5e-30 104.6 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS83048.1 - 1.1e-28 99.7 0.3 2.3e-28 98.7 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 RUS83048.1 - 3e-28 97.1 4.4 6.8e-09 35.2 0.0 7.3 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 RUS83048.1 - 3.3e-25 87.5 2.9 1.4e-08 34.7 0.0 7.2 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 RUS83048.1 - 1.8e-13 49.9 0.2 4.8e-06 26.3 0.0 6.0 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 RUS83048.1 - 7.8e-12 45.0 5.8 0.00063 19.7 0.0 5.5 5 1 1 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS83048.1 - 1.4e-10 41.2 1.2 0.00013 22.1 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS83048.1 - 4.9e-09 36.0 1.1 0.0084 16.1 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Peptidase_C30 PF05409.13 RUS83048.1 - 0.06 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 YaeQ PF07152.12 RUS83048.1 - 0.065 12.8 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 YaeQ protein WD40 PF00400.32 RUS83049.1 - 6.1e-20 71.2 3.9 2e-06 28.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83049.1 - 2.4e-07 30.9 0.3 0.31 11.4 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS83049.1 - 0.00025 20.1 0.0 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 RUS83049.1 - 0.00095 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40_3 PF15911.5 RUS83049.1 - 0.006 16.6 0.8 2.5 8.2 0.0 3.7 3 1 1 4 4 4 1 WD domain, G-beta repeat WD40_like PF17005.5 RUS83049.1 - 0.011 15.1 0.0 0.054 12.8 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain Cornichon PF03311.14 RUS83050.1 - 3.3e-41 140.4 7.5 3.8e-41 140.2 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2650 PF10853.8 RUS83050.1 - 0.0095 15.6 0.7 0.033 13.9 0.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) DUF3671 PF12420.8 RUS83050.1 - 0.023 14.7 0.4 0.041 14.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function adh_short PF00106.25 RUS83051.1 - 2.1e-34 118.7 0.2 7.9e-33 113.6 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS83051.1 - 2.5e-24 86.1 0.0 1.2e-23 84.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS83051.1 - 1.8e-05 24.7 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS83051.1 - 0.0035 16.9 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Nucleotid_trans PF03407.16 RUS83051.1 - 0.01 15.8 0.6 3 7.7 0.1 2.6 3 0 0 3 3 3 0 Nucleotide-diphospho-sugar transferase THF_DHG_CYH_C PF02882.19 RUS83051.1 - 0.14 11.5 0.1 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TALPID3 PF15324.6 RUS83052.1 - 8.8e-84 282.1 107.4 6.8e-80 269.2 71.5 3.1 2 1 1 3 3 3 2 Hedgehog signalling target IRF-2BP1_2 PF11261.8 RUS83053.1 - 2.9e-32 110.0 0.6 5.7e-32 109.0 0.6 1.5 1 0 0 1 1 1 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.25 RUS83053.1 - 0.0036 17.1 6.7 0.0093 15.8 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS83053.1 - 0.046 13.6 7.4 0.16 11.9 7.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS83053.1 - 2.7 7.9 11.5 0.074 12.9 4.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS83053.1 - 9.1 6.7 11.1 0.91 9.9 6.2 2.0 2 0 0 2 2 2 0 Ring finger domain Atg8 PF02991.16 RUS83054.1 - 5.9e-38 129.2 0.4 7.5e-38 128.9 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RUS83054.1 - 1.4e-05 25.4 0.1 2.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Glyco_hydro_65m PF03632.15 RUS83055.1 - 2.3e-53 181.4 0.0 1.6e-33 116.1 0.0 3.2 1 1 2 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 RUS83055.1 - 1.2e-07 30.6 0.0 0.026 12.9 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_92 PF07971.12 RUS83055.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 PAN_1 PF00024.26 RUS83056.1 - 7.2e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 PAN domain TaqI_C PF12950.7 RUS83056.1 - 0.0018 18.3 0.1 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 TaqI-like C-terminal specificity domain DUF1664 PF07889.12 RUS83056.1 - 0.0071 16.4 31.3 0.35 10.9 2.6 6.4 2 2 4 6 6 6 3 Protein of unknown function (DUF1664) Fez1 PF06818.15 RUS83056.1 - 0.42 11.0 37.9 0.023 15.2 6.0 4.2 1 1 3 4 4 4 0 Fez1 TMP_2 PF06791.13 RUS83056.1 - 0.49 10.0 7.4 10 5.7 1.7 3.9 1 1 3 4 4 4 0 Prophage tail length tape measure protein DUF2087 PF09860.9 RUS83056.1 - 0.78 9.9 5.9 1.4 9.1 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2087) NPV_P10 PF05531.12 RUS83056.1 - 4.7 7.7 27.7 3.4 8.2 1.5 6.9 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein LSM PF01423.22 RUS83057.1 - 8e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain C2 PF00168.30 RUS83059.1 - 2.4e-39 133.8 0.5 1.6e-20 73.3 0.1 3.5 3 0 0 3 3 3 2 C2 domain BChl_A PF02327.17 RUS83059.1 - 0.066 12.0 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 Bacteriochlorophyll A protein SMP_LBD PF17047.5 RUS83059.1 - 0.11 12.0 0.6 12 5.3 0.0 3.1 3 0 0 3 3 3 0 Synaptotagmin-like mitochondrial-lipid-binding domain 3HCDH_N PF02737.18 RUS83060.1 - 6.5e-45 153.2 0.1 9.2e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 RUS83060.1 - 5.4e-13 48.6 12.6 1.1e-12 47.5 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_2 PF03446.15 RUS83060.1 - 3.8e-09 36.9 0.1 4.1e-07 30.3 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 RUS83060.1 - 9.4e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Prok-RING_4 PF14447.6 RUS83060.1 - 2.5e-05 24.0 13.2 3e-05 23.8 11.7 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 F420_oxidored PF03807.17 RUS83060.1 - 0.00017 22.1 0.1 0.00061 20.3 0.1 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-RING_2 PF13639.6 RUS83060.1 - 0.00035 20.8 14.9 0.0013 19.1 14.9 2.0 1 0 0 1 1 1 1 Ring finger domain ApbA PF02558.16 RUS83060.1 - 0.00072 19.2 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA zf-C3HC4_2 PF13923.6 RUS83060.1 - 0.00096 19.0 14.6 0.00096 19.0 14.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_8 PF13450.6 RUS83060.1 - 0.0014 18.8 0.1 0.003 17.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RUS83060.1 - 0.0017 18.8 0.1 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-RING_5 PF14634.6 RUS83060.1 - 0.0019 18.2 12.1 0.0041 17.1 12.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain AlaDh_PNT_C PF01262.21 RUS83060.1 - 0.0039 16.5 0.8 0.006 15.9 0.2 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RUS83060.1 - 0.0048 16.5 0.4 0.0085 15.7 0.1 1.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 RUS83060.1 - 0.0054 16.0 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS83060.1 - 0.0057 15.4 0.7 0.015 14.0 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 RUS83060.1 - 0.0068 16.0 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 RUS83060.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 RUS83060.1 - 0.02 14.9 0.3 0.044 13.8 0.3 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 RUS83060.1 - 0.034 14.4 0.1 0.098 12.9 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 RUS83060.1 - 0.046 14.2 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pox_mRNA-cap PF03341.13 RUS83060.1 - 0.095 12.0 0.3 0.14 11.4 0.3 1.1 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit FAD_binding_3 PF01494.19 RUS83060.1 - 0.098 11.9 0.2 0.25 10.5 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 RUS83060.1 - 0.14 11.2 0.2 0.31 10.1 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain zf-RING_11 PF17123.5 RUS83060.1 - 1.6 8.5 9.4 1.5 8.6 5.5 2.9 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 RUS83060.1 - 4.7 7.3 9.0 16 5.6 9.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 RUS83060.1 - 8.5 6.5 10.6 22 5.2 5.6 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Spectrin PF00435.21 RUS83061.1 - 7.2e-11 42.5 10.6 4.3e-05 23.9 1.9 3.7 3 0 0 3 3 3 2 Spectrin repeat IGFBP PF00219.18 RUS83062.1 - 4.7e-06 27.2 20.8 4.7e-06 27.2 20.8 2.0 2 0 0 2 2 2 1 Insulin-like growth factor binding protein 7tm_1 PF00001.21 RUS83063.1 - 3e-05 23.5 1.5 3e-05 23.5 1.5 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Gemini_mov PF01708.16 RUS83063.1 - 0.21 11.4 2.5 0.31 10.8 0.1 2.7 2 0 0 2 2 2 0 Geminivirus putative movement protein Podoplanin PF05808.11 RUS83063.1 - 0.35 11.0 8.7 0.036 14.2 1.3 2.4 2 0 0 2 2 2 0 Podoplanin Orf78 PF06024.12 RUS83063.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.6 3 1 1 4 4 4 0 Orf78 (ac78) 7tm_1 PF00001.21 RUS83064.1 - 0.00094 18.6 13.5 0.0018 17.7 13.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS83064.1 - 0.007 15.7 3.6 0.007 15.7 2.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Fz PF01392.22 RUS83066.1 - 4e-27 95.0 3.6 4e-27 95.0 3.6 1.9 2 0 0 2 2 2 1 Fz domain Spt20 PF12090.8 RUS83066.1 - 0.11 12.1 9.8 0.17 11.5 9.8 1.2 1 0 0 1 1 1 0 Spt20 family TSGP1 PF07771.11 RUS83066.1 - 0.16 12.1 3.6 0.27 11.4 3.6 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF4834 PF16118.5 RUS83066.1 - 0.32 12.0 3.6 0.61 11.1 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NTR PF01759.21 RUS83067.1 - 4.8e-11 42.4 0.2 9.2e-11 41.5 0.2 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module COesterase PF00135.28 RUS83068.1 - 7e-63 213.2 0.0 3.8e-50 171.2 0.0 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS83068.1 - 0.0085 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SAPS PF04499.15 RUS83068.1 - 0.36 9.6 6.1 0.53 9.0 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAP PF00188.26 RUS83069.1 - 5.5e-10 40.1 0.2 6.3e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SIN1_PH PF16979.5 RUS83070.1 - 5.6e-31 107.1 0.2 1.1e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 RUS83070.1 - 3e-30 105.2 0.0 9e-30 103.7 0.0 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1 PF05422.12 RUS83070.1 - 1.4e-19 71.1 16.1 1.9e-18 67.4 7.5 3.9 3 1 0 3 3 3 1 Stress-activated map kinase interacting protein 1 (SIN1) Glyco_trans_2_3 PF13632.6 RUS83070.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Use1 PF09753.9 RUS83070.1 - 7.4 6.2 11.5 0.21 11.3 0.4 3.0 2 1 1 3 3 3 0 Membrane fusion protein Use1 PAP2 PF01569.21 RUS83072.1 - 1.1e-19 70.5 7.7 2e-19 69.7 7.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RUS83072.1 - 5.3e-07 29.5 6.6 8.6e-07 28.8 6.6 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RUS83072.1 - 0.0015 19.0 5.2 0.0015 19.0 5.2 2.4 1 1 1 2 2 2 1 PAP2 superfamily C-terminal NCE101 PF11654.8 RUS83072.1 - 0.059 13.1 0.4 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 Acetyltransf_16 PF05301.11 RUS83073.1 - 7.7e-69 230.9 0.0 1.2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 RUS83073.1 - 0.036 14.5 0.2 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DNA_pol_phi PF04931.13 RUS83074.1 - 0.013 13.7 43.5 0.016 13.4 43.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RUS83074.1 - 0.017 13.9 2.2 0.018 13.8 2.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 RUS83074.1 - 0.082 11.2 20.8 0.11 10.8 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS83074.1 - 0.11 10.7 28.4 0.14 10.3 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS83074.1 - 0.43 9.9 19.1 0.59 9.5 19.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 RUS83074.1 - 0.82 8.0 22.1 1.1 7.7 22.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF1754 PF08555.10 RUS83074.1 - 1.8 9.4 8.0 3 8.7 8.0 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2076 PF09849.9 RUS83074.1 - 2.4 8.1 26.9 3.4 7.7 26.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CNDH2_C PF16858.5 RUS83074.1 - 4.4 7.1 11.7 6.2 6.6 11.7 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_B_2 PF03175.13 RUS83075.1 - 8.8e-08 31.4 4.3 5.8e-07 28.7 1.5 2.9 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral zf-C2H2_4 PF13894.6 RUS83075.1 - 1.6e-05 25.3 30.2 0.0054 17.5 2.2 5.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS83075.1 - 0.00053 19.9 0.3 0.00053 19.9 0.3 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS83075.1 - 0.0061 17.0 1.3 0.0061 17.0 1.3 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type Vsr PF03852.15 RUS83075.1 - 0.018 14.9 0.6 0.063 13.1 0.6 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr zf-H2C2_2 PF13465.6 RUS83075.1 - 0.029 14.8 0.1 0.029 14.8 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS83075.1 - 1.1 9.1 6.7 0.53 10.1 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RUS83075.1 - 5 7.5 12.7 0.1 12.9 3.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 RUS83075.1 - 9.7 6.9 11.8 2 9.1 5.0 3.1 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats MMR_HSR1 PF01926.23 RUS83076.1 - 2.3e-14 53.4 0.2 1.1e-13 51.2 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS83076.1 - 2.4e-07 30.4 0.2 4.4e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS83076.1 - 2.8e-05 24.1 0.1 0.0072 16.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RUS83076.1 - 0.00074 19.6 0.4 0.00074 19.6 0.4 2.3 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 RUS83076.1 - 0.01 15.4 0.0 2.7 7.5 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 RUS83076.1 - 0.029 13.8 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.16 RUS83076.1 - 0.19 11.0 0.1 0.57 9.5 0.0 1.7 2 0 0 2 2 2 0 AIG1 family CPSF_A PF03178.15 RUS83077.1 - 4.9e-101 338.3 0.0 8.4e-101 337.5 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 RUS83077.1 - 1.2e-75 255.0 0.0 3.4e-75 253.6 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2933 PF11666.8 RUS83077.1 - 0.06 13.4 0.6 0.12 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) CABIT PF12736.7 RUS83078.1 - 8.7e-19 67.9 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, 7tm_1 PF00001.21 RUS83079.1 - 5e-10 39.1 25.0 7.8e-10 38.5 25.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4271 PF14093.6 RUS83079.1 - 0.088 12.7 31.9 0.13 12.2 18.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) 7TM_GPCR_Srx PF10328.9 RUS83079.1 - 0.16 11.6 27.3 0.1 12.2 11.8 3.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx TMIE PF16038.5 RUS83079.1 - 3.7 7.5 5.9 0.96 9.3 1.7 2.2 2 0 0 2 2 2 0 TMIE protein Flocculin PF00624.18 RUS83080.1 - 0.65 10.3 4.8 1.9 8.8 4.8 1.8 1 0 0 1 1 1 0 Flocculin repeat Tim29 PF10171.9 RUS83081.1 - 5e-48 162.8 0.0 5.6e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 DUF572 PF04502.13 RUS83082.1 - 1.3e-47 163.0 20.8 1.3e-47 163.0 20.8 2.2 1 1 1 2 2 2 1 Family of unknown function (DUF572) Cadherin_3 PF16184.5 RUS83083.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like Steroid_dh PF02544.16 RUS83085.1 - 4.4e-32 111.1 3.7 4.4e-32 111.1 3.7 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 RUS83085.1 - 0.00011 21.9 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 RUS83086.1 - 1.5e-17 63.6 8.7 0.0014 19.4 0.2 8.8 10 0 0 10 10 10 4 WD domain, G-beta repeat ATG16 PF08614.11 RUS83086.1 - 0.00016 21.9 45.4 0.00079 19.7 28.2 5.5 2 1 4 6 6 6 2 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 RUS83086.1 - 0.00063 20.0 0.2 3.9 7.8 0.1 5.4 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain YabA PF06156.13 RUS83086.1 - 0.0032 18.1 9.5 0.0032 18.1 9.5 6.8 2 2 3 6 6 6 2 Initiation control protein YabA Trans_reg_C PF00486.28 RUS83086.1 - 0.13 12.4 2.7 14 5.8 0.1 3.4 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal 2OG-FeII_Oxy_2 PF13532.6 RUS83087.1 - 1e-08 35.6 0.8 5.4e-08 33.3 0.7 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LSM PF01423.22 RUS83088.1 - 2.1e-16 59.4 0.0 3.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RUS83088.1 - 0.15 12.2 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain GRP PF07172.11 RUS83088.1 - 3.6 8.3 23.6 5.4 7.8 23.6 1.2 1 0 0 1 1 1 0 Glycine rich protein family Actin PF00022.19 RUS83089.1 - 2.5e-150 500.7 0.0 8e-150 499.0 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 RUS83090.1 - 1.2e-116 389.7 0.0 7.6e-83 278.4 0.0 2.7 1 1 1 2 2 2 2 Actin DOMON PF03351.17 RUS83091.1 - 2.7e-13 50.2 0.1 4.2e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 RUS83091.1 - 5.9e-06 26.5 10.8 1.4e-05 25.3 7.6 2.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF202 PF02656.15 RUS83091.1 - 0.16 12.4 4.6 1.5 9.3 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4199 PF13858.6 RUS83091.1 - 0.42 11.0 5.5 0.22 11.9 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) TspO_MBR PF03073.15 RUS83091.1 - 9.1 6.3 11.1 1.9e+02 2.1 11.1 2.6 1 1 0 1 1 1 0 TspO/MBR family Reeler PF02014.16 RUS83092.1 - 1.3e-24 87.4 0.0 2.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reeler domain PA-IL PF07828.12 RUS83092.1 - 0.041 13.9 0.1 0.11 12.5 0.1 1.7 1 1 0 1 1 1 0 PA-IL-like protein DUF2353 PF09789.9 RUS83094.1 - 5.1e-06 26.1 1.1 5.8e-06 25.9 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) SlyX PF04102.12 RUS83094.1 - 0.031 14.9 0.1 0.043 14.4 0.1 1.3 1 0 0 1 1 1 0 SlyX FAM76 PF16046.5 RUS83095.1 - 2.6 7.3 22.5 1.7 7.9 15.8 2.4 1 1 1 2 2 2 0 FAM76 protein Csm1_N PF18504.1 RUS83095.1 - 3.6 8.0 23.7 0.33 11.3 0.8 5.4 3 2 3 6 6 6 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 RUS83095.1 - 4.3 7.4 29.9 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 RUS83095.1 - 7.2 5.4 35.4 0.65 8.8 18.3 3.2 1 1 0 2 2 2 0 Spc7 kinetochore protein RVT_1 PF00078.27 RUS83096.1 - 0.0065 16.0 0.1 0.028 13.9 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fibrinogen_C PF00147.18 RUS83097.1 - 3.2e-54 184.1 3.3 4.9e-54 183.5 3.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CorA PF01544.18 RUS83097.1 - 0.13 11.5 0.8 0.22 10.8 0.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 RUS83097.1 - 0.95 9.5 5.4 0.51 10.4 0.9 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_1 PF00036.32 RUS83098.1 - 3e-29 98.4 3.0 8e-07 28.2 0.1 5.7 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 RUS83098.1 - 5e-27 94.1 0.2 1e-10 41.9 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS83098.1 - 1.8e-26 89.7 1.2 2.4e-06 27.0 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 RUS83098.1 - 8.3e-24 83.2 0.0 7e-10 38.6 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS83098.1 - 2.7e-21 74.0 1.1 0.00013 21.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS83098.1 - 0.0012 19.1 0.0 9 6.7 0.0 3.5 3 2 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.11 RUS83098.1 - 0.065 13.4 0.0 10 6.3 0.0 3.1 4 0 0 4 4 4 0 EF hand EF-hand_10 PF14788.6 RUS83098.1 - 0.07 13.0 0.0 5.7 6.9 0.0 2.9 3 0 0 3 3 3 0 EF hand GUN4 PF05419.12 RUS83098.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 GUN4-like Cys_rich_FGFR PF00839.17 RUS83099.1 - 9.6e-158 512.5 116.2 1.1e-12 47.9 0.2 16.4 16 0 0 16 16 16 16 Cysteine rich repeat DUF445 PF04286.12 RUS83099.1 - 0.1 12.4 3.0 11 5.6 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF445) LSM PF01423.22 RUS83100.1 - 8.1e-36 121.5 2.4 1e-18 66.8 0.2 2.0 2 0 0 2 2 2 2 LSM domain Hfq PF17209.3 RUS83100.1 - 0.021 14.5 0.1 7.2 6.3 0.0 2.5 3 0 0 3 3 3 0 Hfq protein BPL_C PF02237.17 RUS83100.1 - 0.032 14.1 0.1 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Ribosomal_L22 PF00237.19 RUS83101.1 - 7.5e-36 122.5 0.2 1.2e-35 121.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e S1FA PF04689.13 RUS83101.1 - 0.45 10.7 2.4 1.1 9.5 2.4 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA Cnn_1N PF07989.11 RUS83102.1 - 4.7e-18 65.1 2.5 4.7e-18 65.1 2.5 18.7 10 6 9 19 19 19 1 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 RUS83102.1 - 0.0029 17.6 22.8 0.0029 17.6 22.8 15.1 8 3 8 17 17 17 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 RUS83102.1 - 0.0068 16.7 15.0 0.0068 16.7 15.0 15.4 6 3 8 14 14 14 3 Autophagy protein 16 (ATG16) Sorb PF02208.16 RUS83102.1 - 0.067 13.0 0.7 0.19 11.6 0.7 1.8 1 0 0 1 1 1 0 Sorbin homologous domain Shugoshin_N PF07558.11 RUS83102.1 - 0.091 12.6 0.0 0.091 12.6 0.0 6.6 7 0 0 7 7 7 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 RUS83102.1 - 0.47 10.6 0.0 0.47 10.6 0.0 16.5 15 4 3 19 19 19 0 bZIP transcription factor Prenyltrans PF00432.21 RUS83103.1 - 1.3e-32 111.2 4.3 4.5e-07 29.5 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Galactosyl_T PF01762.21 RUS83104.1 - 3.8e-30 105.2 0.0 5.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase PWWP PF00855.17 RUS83107.1 - 8.7e-37 125.4 1.7 1.9e-19 69.8 0.1 3.4 2 0 0 2 2 2 2 PWWP domain SET PF00856.28 RUS83107.1 - 2.3e-20 73.7 0.1 2.3e-20 73.7 0.1 4.2 4 0 0 4 4 4 1 SET domain AWS PF17907.1 RUS83107.1 - 4.5e-18 65.0 6.2 4.8e-17 61.7 6.2 3.0 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 RUS83107.1 - 6.4e-13 48.4 70.9 5.9e-07 29.3 11.3 6.8 4 2 2 6 6 6 4 PHD-finger C5HCH PF17982.1 RUS83107.1 - 1.5e-09 37.9 9.6 1.5e-09 37.9 9.6 4.3 5 0 0 5 5 5 1 NSD Cys-His rich domain zf-HC5HC2H_2 PF13832.6 RUS83107.1 - 0.013 15.7 2.6 0.013 15.7 2.6 6.5 2 2 3 6 6 6 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RUS83107.1 - 0.025 14.8 75.6 0.18 12.1 9.8 6.9 2 2 5 7 7 7 0 PHD-like zinc-binding domain F-box-like PF12937.7 RUS83108.1 - 3.5e-11 42.8 1.2 3.5e-11 42.8 1.2 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 RUS83108.1 - 1.5e-09 37.9 13.0 0.9 10.0 0.0 8.3 6 2 0 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 RUS83108.1 - 2.4e-06 27.3 1.6 2.4e-06 27.3 1.6 3.3 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 RUS83108.1 - 0.0037 17.2 7.2 67 3.9 0.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat LRR_8 PF13855.6 RUS83108.1 - 0.072 12.9 7.0 6.8 6.5 0.0 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_5 PF13306.6 RUS83108.1 - 0.31 11.0 6.0 0.36 10.8 0.5 3.5 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) His_Phos_2 PF00328.22 RUS83110.1 - 7.1e-20 71.7 0.0 1.3e-10 41.2 0.1 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.22 RUS83111.1 - 4.2e-101 338.7 0.0 6.4e-101 338.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA PF00004.29 RUS83112.1 - 5.1e-25 88.4 0.0 4.3e-24 85.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3523 PF12037.8 RUS83112.1 - 7.9e-07 28.7 0.2 1.2e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA_16 PF13191.6 RUS83112.1 - 2.4e-05 24.8 0.0 0.0015 19.0 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 RUS83112.1 - 3.7e-05 23.5 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS83112.1 - 4.7e-05 23.7 0.1 0.087 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 RUS83112.1 - 4.9e-05 22.8 0.1 0.00058 19.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RUS83112.1 - 0.00028 21.1 0.1 0.00054 20.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS83112.1 - 0.00028 20.9 0.1 0.0031 17.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RUS83112.1 - 0.0007 19.4 0.2 0.0015 18.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS83112.1 - 0.0025 18.4 0.1 0.0092 16.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 RUS83112.1 - 0.0046 17.3 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zot PF05707.12 RUS83112.1 - 0.0062 16.2 0.4 0.092 12.4 0.1 2.2 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.17 RUS83112.1 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 RUS83112.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 RUS83112.1 - 0.014 15.6 0.4 0.18 11.9 0.0 2.6 2 2 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 RUS83112.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS83112.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 RUS83112.1 - 0.015 14.6 0.0 0.039 13.2 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 RUS83112.1 - 0.018 15.0 0.1 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 RUS83112.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 RUS83112.1 - 0.022 13.9 0.0 0.053 12.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 RUS83112.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 RUS83112.1 - 0.028 14.0 0.3 0.089 12.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 RUS83112.1 - 0.032 14.1 0.0 0.093 12.6 0.0 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_lid_3 PF17862.1 RUS83112.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain AAA_7 PF12775.7 RUS83112.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RUS83112.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.17 RUS83112.1 - 0.09 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA-ATPase_like PF09820.9 RUS83112.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AAA-ATPase AAA_17 PF13207.6 RUS83112.1 - 0.094 13.1 0.6 0.28 11.6 0.6 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RUS83112.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RUS83112.1 - 0.18 10.9 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pribosyltran_N PF13793.6 RUS83113.1 - 1.3e-47 160.6 0.0 1.6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase UQ_con PF00179.26 RUS83114.1 - 1.9e-43 147.5 0.0 2.4e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 RUS83114.1 - 4.7e-08 32.8 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 RUS83114.1 - 2.1e-06 27.5 0.0 4.2e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RUS83114.1 - 0.00055 20.2 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 RUS83114.1 - 0.044 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 RUS83114.1 - 0.045 13.4 0.0 0.068 12.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_M19 PF01244.21 RUS83115.1 - 3.3e-75 253.2 0.1 3.7e-75 253.1 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4468 PF14730.6 RUS83115.1 - 0.012 15.9 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Pyr_excise PF03013.14 RUS83115.1 - 0.044 13.8 0.1 2.5 8.1 0.0 2.4 2 1 0 2 2 2 0 Pyrimidine dimer DNA glycosylase PCI PF01399.27 RUS83116.1 - 5.9e-18 65.3 0.1 8.2e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 PCI domain Abhydro_lipase PF04083.16 RUS83117.1 - 1.1e-23 82.6 0.0 2.9e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RUS83117.1 - 1.2e-22 80.9 1.1 1.2e-21 77.5 1.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS83117.1 - 4e-07 29.5 0.0 5.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS83117.1 - 0.0012 19.4 0.3 0.0016 19.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PP-binding PF00550.25 RUS83119.1 - 7.6e-13 48.6 0.1 8.8e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAND PF01342.21 RUS83120.1 - 6.4e-24 83.5 0.0 1.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 SAND domain Nif11 PF07862.11 RUS83120.1 - 0.36 11.2 2.9 0.95 9.8 2.9 1.8 1 0 0 1 1 1 0 Nif11 domain NUDE_C PF04880.13 RUS83121.1 - 1.8e-35 123.0 0.2 1.8e-35 123.0 0.2 2.5 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 RUS83121.1 - 0.0022 18.0 35.8 0.0087 16.1 26.9 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 RUS83121.1 - 0.011 15.6 8.8 0.011 15.6 8.8 4.2 1 1 3 4 4 4 0 Prefoldin subunit SlyX PF04102.12 RUS83121.1 - 0.018 15.7 4.5 0.018 15.7 4.5 4.1 2 1 3 5 5 4 0 SlyX Fez1 PF06818.15 RUS83121.1 - 0.032 14.7 27.2 0.044 14.2 7.5 2.3 1 1 1 2 2 2 0 Fez1 LXG PF04740.12 RUS83121.1 - 0.035 13.8 16.8 0.063 13.0 15.8 2.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily PRKG1_interact PF15898.5 RUS83121.1 - 0.098 13.6 32.3 0.95 10.4 14.3 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Tektin PF03148.14 RUS83121.1 - 0.35 9.6 29.6 0.54 9.0 18.2 2.3 1 1 1 2 2 2 0 Tektin family Lebercilin PF15619.6 RUS83121.1 - 0.39 10.4 36.9 0.02 14.5 17.1 2.7 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GIT_CC PF16559.5 RUS83121.1 - 0.47 10.4 21.6 0.27 11.1 6.0 3.7 2 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 RUS83121.1 - 0.47 10.6 21.3 0.18 12.0 8.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 RUS83121.1 - 0.48 10.8 31.0 0.14 12.5 15.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 RUS83121.1 - 0.49 7.9 29.4 0.66 7.4 29.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DIT1_PvcA PF05141.12 RUS83121.1 - 1 8.8 10.9 1.1 8.6 10.1 1.4 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein LPP PF04728.13 RUS83121.1 - 1.1 9.7 5.7 5.6 7.4 0.3 3.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Prominin PF05478.11 RUS83121.1 - 1.1 7.1 13.8 0.26 9.2 9.9 1.6 1 1 0 1 1 1 0 Prominin Pox_A_type_inc PF04508.12 RUS83121.1 - 1.1 9.2 0.1 1.1 9.2 0.1 6.8 8 0 0 8 8 7 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 RUS83121.1 - 1.2 8.0 33.7 0.86 8.4 18.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SLATT_fungal PF18142.1 RUS83121.1 - 1.3 9.0 7.8 8.3 6.4 0.6 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain FUSC PF04632.12 RUS83121.1 - 1.4 7.4 7.0 1.9 6.9 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.11 RUS83121.1 - 1.5 9.5 23.1 1.2 9.7 2.8 4.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ACR_tran PF00873.19 RUS83121.1 - 1.6 6.3 7.2 2 5.9 7.2 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SKA2 PF16740.5 RUS83121.1 - 2.1 8.2 18.8 0.27 11.0 8.4 2.8 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Uso1_p115_C PF04871.13 RUS83121.1 - 2.4 8.5 35.2 1.9 8.8 25.2 2.9 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2252 PF10009.9 RUS83121.1 - 2.5 7.1 9.3 3.4 6.6 9.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF1664 PF07889.12 RUS83121.1 - 2.5 8.1 15.4 2.6 8.1 5.8 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) ERM PF00769.19 RUS83121.1 - 2.6 7.8 35.4 7.8 6.2 35.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF2353 PF09789.9 RUS83121.1 - 2.7 7.3 31.2 11 5.2 30.3 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.6 RUS83121.1 - 2.9 7.9 34.4 3.6 7.6 16.4 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion COG5 PF10392.9 RUS83121.1 - 3.1 8.0 13.8 0.96 9.6 8.9 2.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 ATG16 PF08614.11 RUS83121.1 - 3.8 7.7 38.3 3.6 7.8 14.5 2.5 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Vps51 PF08700.11 RUS83121.1 - 4.2 7.5 14.9 0.44 10.7 5.6 3.4 1 1 3 4 4 4 0 Vps51/Vps67 Metal_resist PF13801.6 RUS83121.1 - 4.2 7.6 12.4 5.3 7.2 2.4 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Laminin_II PF06009.12 RUS83121.1 - 6.8 6.7 20.1 7.5 6.6 5.6 2.5 1 1 1 2 2 2 0 Laminin Domain II YabA PF06156.13 RUS83121.1 - 8.8 7.0 27.8 1.4 9.6 5.1 4.1 1 1 3 4 4 4 0 Initiation control protein YabA Golgin_A5 PF09787.9 RUS83121.1 - 9.9 5.5 33.8 0.11 11.9 17.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 MT PF12777.7 RUS83122.1 - 2.5e-17 63.0 0.5 4.4e-17 62.1 0.5 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor C2 PF00168.30 RUS83123.1 - 5e-19 68.5 0.1 1.5e-14 54.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain GcnA_N PF18229.1 RUS83123.1 - 0.031 14.3 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain EphA2_TM PF14575.6 RUS83123.1 - 0.12 13.2 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycoprotein_G PF00802.19 RUS83124.1 - 0.27 10.6 1.0 0.4 10.0 0.5 1.5 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G DBB PF14545.6 RUS83125.1 - 3.3e-10 40.0 0.0 5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, PPP4R2 PF09184.11 RUS83126.1 - 0.0083 15.8 10.6 0.0083 15.8 10.6 2.8 2 1 0 2 2 2 1 PPP4R2 DUF4766 PF15973.5 RUS83126.1 - 1.9 9.1 9.3 7.2 7.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) LZ_Tnp_IS66 PF13007.7 RUS83127.1 - 0.18 12.6 7.9 4.6 8.1 0.0 4.7 2 2 1 3 3 3 0 Transposase C of IS166 homeodomain AT_hook PF02178.19 RUS83127.1 - 6.8 6.9 11.0 0.53 10.3 4.9 2.6 2 0 0 2 2 2 0 AT hook motif Sec23_trunk PF04811.15 RUS83129.1 - 8.1e-81 271.2 0.1 1.3e-80 270.5 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RUS83129.1 - 2.7e-27 94.6 0.0 5.2e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RUS83129.1 - 6.2e-18 65.3 0.0 1.5e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RUS83129.1 - 1e-17 63.9 1.3 2.3e-17 62.8 1.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RUS83129.1 - 2.4e-10 40.2 0.1 7.9e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat AAA_12 PF13087.6 RUS83131.1 - 2.8e-36 125.0 0.1 5.5e-36 124.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS83131.1 - 6.4e-25 88.4 5.3 8.2e-13 48.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 RUS83131.1 - 1.1e-10 41.6 0.0 1.4e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS83131.1 - 9.6e-07 29.2 0.1 1.9e-05 25.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 RUS83131.1 - 1e-06 28.8 0.7 3.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCCH PF00642.24 RUS83131.1 - 5.2e-06 26.2 2.3 1.3e-05 24.9 2.3 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PhoH PF02562.16 RUS83131.1 - 4.1e-05 23.1 0.0 0.015 14.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein zf_CCCH_4 PF18345.1 RUS83131.1 - 6.8e-05 22.8 1.3 0.00017 21.5 1.3 1.7 1 0 0 1 1 1 1 Zinc finger domain UvrD-helicase PF00580.21 RUS83131.1 - 7.3e-05 22.4 1.8 0.0038 16.8 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain zf-CCCH_4 PF18044.1 RUS83131.1 - 0.00034 20.3 0.6 0.00078 19.2 0.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger PAM2 PF07145.15 RUS83131.1 - 0.0005 19.6 1.8 0.0017 17.9 1.8 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_22 PF13401.6 RUS83131.1 - 0.0032 17.7 0.0 0.017 15.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 RUS83131.1 - 0.0043 17.5 1.3 0.012 16.1 1.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_7 PF12775.7 RUS83131.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Helicase_RecD PF05127.14 RUS83131.1 - 0.022 14.6 0.0 0.091 12.6 0.0 2.1 1 1 0 1 1 1 0 Helicase AAA_16 PF13191.6 RUS83131.1 - 0.041 14.3 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 RUS83131.1 - 0.068 13.2 0.0 3.6 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 RUS83131.1 - 0.083 13.1 0.6 13 6.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS83131.1 - 0.096 13.6 0.1 2.8 9.0 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat SRP54 PF00448.22 RUS83131.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.6 RUS83131.1 - 0.19 11.6 0.1 0.84 9.5 0.1 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain TPR_16 PF13432.6 RUS83131.1 - 2 9.1 4.3 41 4.9 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DWNN PF08783.11 RUS83133.1 - 1.6e-24 85.9 0.3 7.8e-24 83.8 0.1 2.4 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 RUS83133.1 - 1.9e-06 27.6 4.8 1.9e-06 27.6 4.8 2.2 2 0 0 2 2 2 1 Zinc knuckle U-box PF04564.15 RUS83133.1 - 0.0021 18.2 0.0 0.0069 16.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-CCHC PF00098.23 RUS83133.1 - 0.29 11.3 2.7 0.63 10.2 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_3 PF13920.6 RUS83133.1 - 0.35 10.7 19.6 0.021 14.7 12.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS83133.1 - 4.9 7.1 23.2 0.064 13.1 14.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RUS83133.1 - 5.7 6.8 12.9 13 5.6 12.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 RUS83133.1 - 7.1 7.1 22.8 0.044 14.1 14.5 1.7 2 0 0 2 2 2 0 Ring finger domain LRR_8 PF13855.6 RUS83134.1 - 6.9e-18 64.2 11.6 2.6e-08 33.5 0.3 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS83134.1 - 2.5e-13 50.0 12.5 0.00011 22.5 2.2 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS83134.1 - 5.8e-06 26.0 6.2 0.21 11.7 0.0 4.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 RUS83134.1 - 0.00014 22.0 9.1 1 10.2 0.2 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 RUS83134.1 - 0.00015 21.3 4.2 0.00037 20.0 0.4 2.7 2 1 1 3 3 3 2 Leucine-rich repeat EF-G-binding_N PF07299.11 RUS83134.1 - 0.035 14.6 5.4 2.1 8.9 0.3 2.5 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal BUD22 PF09073.10 RUS83135.1 - 2.2e-05 24.0 29.0 2.8e-05 23.7 29.0 1.1 1 0 0 1 1 1 1 BUD22 NARP1 PF12569.8 RUS83135.1 - 5.4e-05 22.3 22.9 6.6e-05 22.0 22.9 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 NOA36 PF06524.12 RUS83135.1 - 7.6e-05 22.2 16.5 9.7e-05 21.8 16.5 1.1 1 0 0 1 1 1 1 NOA36 protein DUF4746 PF15928.5 RUS83135.1 - 0.00015 21.3 25.2 0.00018 21.0 25.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DUF5427 PF10310.9 RUS83135.1 - 0.00042 19.4 19.0 0.00054 19.1 19.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF913 PF06025.12 RUS83135.1 - 0.00043 19.4 8.3 0.00052 19.1 8.3 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 RUS83135.1 - 0.00046 20.1 12.2 0.00055 19.8 12.2 1.1 1 0 0 1 1 1 1 AAA domain Afi1 PF07792.12 RUS83135.1 - 0.00055 20.4 9.5 0.00074 20.0 9.5 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2828 PF11443.8 RUS83135.1 - 0.00062 18.0 10.6 0.00069 17.8 10.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) RNA_pol_3_Rpc31 PF11705.8 RUS83135.1 - 0.00087 19.6 32.4 0.0012 19.2 32.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.22 RUS83135.1 - 0.0011 18.3 9.3 0.0014 18.0 9.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter FancD2 PF14631.6 RUS83135.1 - 0.0019 15.7 12.7 0.0022 15.5 12.7 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Dynactin_p62 PF05502.13 RUS83135.1 - 0.002 17.0 6.9 0.0022 16.8 6.9 1.1 1 0 0 1 1 1 1 Dynactin p62 family SAPS PF04499.15 RUS83135.1 - 0.002 17.0 6.6 0.002 17.0 6.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF2201_N PF13203.6 RUS83135.1 - 0.0022 17.6 6.0 0.0026 17.4 6.0 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain Presenilin PF01080.17 RUS83135.1 - 0.0036 16.1 14.3 0.0044 15.8 14.3 1.1 1 0 0 1 1 1 1 Presenilin Vfa1 PF08432.10 RUS83135.1 - 0.0039 17.5 28.3 0.007 16.7 28.3 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Cellulose_synt PF03552.14 RUS83135.1 - 0.0084 14.7 8.3 0.01 14.4 8.3 1.1 1 0 0 1 1 1 1 Cellulose synthase Rrn6 PF10214.9 RUS83135.1 - 0.0094 14.5 6.8 0.01 14.4 6.8 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor NPR3 PF03666.13 RUS83135.1 - 0.011 14.5 22.0 0.014 14.2 22.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 RUS83135.1 - 0.019 13.3 8.6 0.02 13.2 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.6 RUS83135.1 - 0.024 14.6 28.8 0.045 13.7 28.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO FGF-BP1 PF06473.12 RUS83135.1 - 0.027 14.3 22.4 0.036 13.9 22.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SR-25 PF10500.9 RUS83135.1 - 0.03 14.0 33.9 0.042 13.4 33.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Slu7 PF11708.8 RUS83135.1 - 0.035 13.9 27.8 0.048 13.4 27.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Hid1 PF12722.7 RUS83135.1 - 0.035 12.3 13.1 0.042 12.0 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2151 PF10221.9 RUS83135.1 - 0.036 12.7 17.5 0.044 12.4 17.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator ALMT PF11744.8 RUS83135.1 - 0.046 12.5 11.2 0.051 12.4 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-N PF05238.13 RUS83135.1 - 0.048 13.0 9.2 0.059 12.7 9.2 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pox_Ag35 PF03286.14 RUS83135.1 - 0.064 13.0 34.2 0.095 12.5 34.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Serinc PF03348.15 RUS83135.1 - 0.081 11.8 4.2 0.11 11.4 4.2 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF262 PF03235.14 RUS83135.1 - 0.11 12.7 6.9 0.13 12.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Smg8_Smg9 PF10220.9 RUS83135.1 - 0.11 10.8 9.1 0.12 10.6 9.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 FAM60A PF15396.6 RUS83135.1 - 0.12 12.4 22.3 0.16 12.0 22.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RP-C_C PF11800.8 RUS83135.1 - 0.14 12.2 10.1 0.18 11.9 10.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Rgp1 PF08737.10 RUS83135.1 - 0.22 10.7 9.6 0.25 10.5 9.6 1.1 1 0 0 1 1 1 0 Rgp1 CSG2 PF16965.5 RUS83135.1 - 0.25 10.2 2.7 0.32 9.9 2.7 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator CSRNP_N PF16019.5 RUS83135.1 - 0.27 11.1 20.3 0.37 10.7 20.3 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Scs3p PF10261.9 RUS83135.1 - 0.28 10.7 2.8 0.42 10.1 2.8 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Gti1_Pac2 PF09729.9 RUS83135.1 - 0.3 11.1 18.8 0.42 10.7 18.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family eIF3_subunit PF08597.10 RUS83135.1 - 0.34 10.8 49.3 0.47 10.3 49.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Nop14 PF04147.12 RUS83135.1 - 0.36 9.0 29.0 0.51 8.5 29.0 1.1 1 0 0 1 1 1 0 Nop14-like family SID-1_RNA_chan PF13965.6 RUS83135.1 - 0.47 8.8 5.7 0.54 8.6 5.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RPOL_N PF14700.6 RUS83135.1 - 0.49 9.7 22.3 0.66 9.3 22.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal MCM_bind PF09739.9 RUS83135.1 - 0.59 8.5 16.2 0.68 8.3 16.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF1168 PF06658.12 RUS83135.1 - 0.65 9.8 43.8 1.2 8.9 43.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Dsh_C PF12316.8 RUS83135.1 - 0.72 10.2 2.4 0.89 9.9 2.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PPL5 PF18168.1 RUS83135.1 - 0.74 9.1 18.6 1 8.6 18.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 CDC27 PF09507.10 RUS83135.1 - 0.89 8.9 37.2 1.2 8.5 37.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.19 RUS83135.1 - 0.97 8.3 16.0 1.2 8.0 16.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Kei1 PF08552.11 RUS83135.1 - 1.1 9.1 4.5 1.7 8.5 4.5 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Membralin PF09746.9 RUS83135.1 - 2.2 7.2 11.0 2.6 7.0 11.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF789 PF05623.12 RUS83135.1 - 2.2 7.9 10.6 2.8 7.5 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Ureide_permease PF07168.11 RUS83135.1 - 2.3 6.9 12.0 3.1 6.4 12.0 1.2 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 RUS83135.1 - 2.5 7.6 27.8 3.7 7.0 27.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ESM4 PF15952.5 RUS83135.1 - 2.7 8.4 15.8 4.2 7.8 15.8 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family VIR_N PF15912.5 RUS83135.1 - 3 7.4 17.2 3.6 7.1 17.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Red1 PF07964.11 RUS83135.1 - 3.1 5.9 29.7 3.9 5.6 29.7 1.0 1 0 0 1 1 1 0 Rec10 / Red1 SLC12 PF03522.15 RUS83135.1 - 4.5 6.2 21.0 5.9 5.8 21.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Band_3_cyto PF07565.13 RUS83135.1 - 4.7 6.9 12.1 6.6 6.5 12.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CobT PF06213.12 RUS83135.1 - 4.8 6.5 29.1 6.5 6.0 29.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 RUS83135.1 - 5.2 6.8 32.7 7.7 6.2 32.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.11 RUS83135.1 - 6.2 5.2 15.9 7.7 4.9 15.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Rtf2 PF04641.12 RUS83135.1 - 9 5.6 35.5 13 5.0 35.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LIM PF00412.22 RUS83136.1 - 2.1e-27 95.1 17.7 1.1e-13 51.1 7.2 2.9 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS83136.1 - 5.5e-07 29.3 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain EGF PF00008.27 RUS83137.1 - 0.072 13.4 7.4 8.5 6.8 1.5 4.0 3 1 0 3 3 3 0 EGF-like domain hEGF PF12661.7 RUS83137.1 - 0.18 12.5 4.6 35 5.2 0.1 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF AF-4 PF05110.13 RUS83138.1 - 0.024 12.7 2.2 0.033 12.3 2.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PC-Esterase PF13839.6 RUS83138.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Serglycin PF04360.12 RUS83138.1 - 0.82 9.6 2.5 1.4 8.9 2.5 1.3 1 0 0 1 1 1 0 Serglycin RRF PF01765.19 RUS83139.1 - 2.2e-36 125.3 0.5 2.9e-36 124.9 0.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor COMP PF11598.8 RUS83139.1 - 0.0028 18.1 3.9 0.68 10.4 0.4 2.4 2 0 0 2 2 2 2 Cartilage oligomeric matrix protein Mer2 PF09074.10 RUS83139.1 - 0.038 13.8 2.9 0.17 11.7 2.2 2.0 1 1 1 2 2 2 0 Mer2 YtxH PF12732.7 RUS83139.1 - 0.18 12.4 2.1 1.6 9.3 1.5 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF3810 PF12725.7 RUS83139.1 - 0.36 10.1 1.7 0.53 9.6 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) zf-H2C2_5 PF13909.6 RUS83144.1 - 0.00035 20.2 0.3 0.00035 20.2 0.3 6.7 7 0 0 7 7 7 3 C2H2-type zinc-finger domain FOXP-CC PF16159.5 RUS83144.1 - 1.7 9.3 21.0 0.2 12.3 3.9 5.3 4 1 1 5 5 5 0 FOXP coiled-coil domain Prok-RING_2 PF14445.6 RUS83144.1 - 5 7.4 11.0 7.3 6.8 0.4 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Pkinase_Tyr PF07714.17 RUS83145.1 - 1.3e-87 293.4 0.0 1.6e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS83145.1 - 1e-45 156.2 0.0 1.4e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS83145.1 - 1.1e-16 60.6 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RUS83145.1 - 6.9e-12 44.8 1.5 8.1e-12 44.6 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RUS83145.1 - 3.2e-10 39.7 0.2 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RUS83145.1 - 2.3e-07 30.4 0.0 7.9e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 RUS83145.1 - 3.6e-05 22.9 0.3 6.6e-05 22.0 0.3 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS83145.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RUS83145.1 - 0.049 13.0 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family T2SSM_b PF10741.9 RUS83145.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Stathmin PF00836.19 RUS83146.1 - 4.3e-09 36.4 23.8 6.4e-09 35.9 23.8 1.3 1 0 0 1 1 1 1 Stathmin family UPF0242 PF06785.11 RUS83146.1 - 0.3 11.2 15.5 0.38 10.8 15.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2913 PF11140.8 RUS83147.1 - 0.0029 17.4 0.1 0.0042 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) SwrA PF17423.2 RUS83147.1 - 0.081 12.9 1.6 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 Swarming motility protein Amidase PF01425.21 RUS83148.1 - 1.1e-60 205.9 0.0 1.5e-60 205.5 0.0 1.1 1 0 0 1 1 1 1 Amidase 7tm_1 PF00001.21 RUS83149.1 - 2.4e-39 135.3 7.4 4.6e-27 95.0 5.0 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS83149.1 - 2.2e-09 37.5 1.9 2.2e-09 37.5 1.9 2.0 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS83149.1 - 1.7e-06 27.6 2.5 1.7e-06 27.6 2.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS83149.1 - 2.4e-05 23.8 10.0 0.0015 18.0 1.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS83149.1 - 0.0078 15.9 3.2 0.0078 15.9 3.2 2.1 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1673 PF07895.11 RUS83149.1 - 1.5 8.5 7.1 0.07 12.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) TetR_C_6 PF13977.6 RUS83150.1 - 0.16 12.2 8.6 0.033 14.4 3.5 2.4 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF87 PF01935.17 RUS83150.1 - 2.2 8.3 4.8 10 6.1 0.0 2.6 1 1 0 2 2 2 0 Helicase HerA, central domain CCAP PF11105.8 RUS83151.1 - 1.8e-07 31.2 0.0 2.5e+02 1.6 0.0 8.9 1 1 9 10 10 10 0 Arthropod cardioacceleratory peptide 2a LRR_3 PF07725.12 RUS83151.1 - 0.037 13.9 18.5 3.3e+02 1.4 0.0 9.9 11 0 0 11 11 11 0 Leucine Rich Repeat BLF1 PF17752.1 RUS83151.1 - 0.72 9.1 41.1 24 4.2 0.2 9.7 1 1 10 11 11 11 0 Burkholderia lethal factor 1 TGF_beta PF00019.20 RUS83152.1 - 6.5e-11 43.1 0.3 1.4e-10 42.0 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain fn3 PF00041.21 RUS83153.1 - 0.00041 20.6 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain MLANA PF14991.6 RUS83153.1 - 0.0023 18.2 0.1 0.0069 16.7 0.1 1.8 1 0 0 1 1 1 1 Protein melan-A TMEM154 PF15102.6 RUS83153.1 - 0.0025 17.7 0.3 0.052 13.5 0.0 2.5 1 1 1 2 2 2 1 TMEM154 protein family Comm PF15957.5 RUS83153.1 - 0.33 11.3 1.5 0.45 10.9 0.1 1.9 2 0 0 2 2 2 0 Commissureless Corona_S2 PF01601.16 RUS83153.1 - 1 7.7 2.5 1.5 7.2 2.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein EGF PF00008.27 RUS83154.1 - 5.3e-12 45.8 49.9 0.0002 21.6 8.6 5.6 5 1 0 5 5 5 4 EGF-like domain EGF_2 PF07974.13 RUS83154.1 - 3.7e-07 30.4 61.9 0.04 14.3 10.8 5.4 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 RUS83154.1 - 0.00022 21.7 51.6 0.0089 16.6 7.2 6.5 7 0 0 7 7 7 4 Human growth factor-like EGF V-SNARE_C PF12352.8 RUS83155.1 - 8.6e-19 67.6 8.0 9.3e-19 67.5 4.5 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 RUS83155.1 - 4.2e-15 55.9 1.8 4.2e-15 55.9 1.8 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 RUS83155.1 - 2.5e-05 24.1 2.0 3.7e-05 23.6 0.3 2.0 2 0 0 2 2 2 1 Sec20 EzrA PF06160.12 RUS83155.1 - 0.03 12.5 3.0 0.053 11.7 0.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Fusion_gly PF00523.18 RUS83155.1 - 0.064 11.5 0.3 0.11 10.7 0.3 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 DHR10 PF18595.1 RUS83155.1 - 0.065 13.3 0.9 0.065 13.3 0.9 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain IFT57 PF10498.9 RUS83155.1 - 1.4 7.8 4.6 0.26 10.2 0.8 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CCDC-167 PF15188.6 RUS83155.1 - 1.6 9.1 10.1 0.73 10.2 0.5 3.3 4 1 0 4 4 4 0 Coiled-coil domain-containing protein 167 Glyco_transf_43 PF03360.16 RUS83156.1 - 2.8e-66 223.3 1.0 3.4e-66 223.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 43 Mononeg_mRNAcap PF14318.6 RUS83156.1 - 0.0094 15.2 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 Mononegavirales mRNA-capping region V Aida_C2 PF14186.6 RUS83157.1 - 2.8e-44 150.3 0.5 3.2e-44 150.1 0.5 1.0 1 0 0 1 1 1 1 Cytoskeletal adhesion SR-25 PF10500.9 RUS83158.1 - 0.056 13.0 9.3 0.091 12.4 9.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 7TM_GPCR_Srw PF10324.9 RUS83158.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw C_tripleX PF02363.19 RUS83158.1 - 1.7 9.1 4.4 24 5.5 0.5 2.5 2 0 0 2 2 2 0 Cysteine rich repeat PAS_11 PF14598.6 RUS83161.1 - 1.2e-16 60.9 2.7 5.3e-16 58.8 0.9 2.6 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 RUS83161.1 - 9.1e-16 57.9 0.2 1.3e-12 47.9 0.0 2.9 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 RUS83161.1 - 1e-05 25.4 0.3 2.4e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 RUS83161.1 - 8.5e-05 22.5 0.2 0.64 10.0 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 RUS83161.1 - 0.0064 16.7 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain Spectrin PF00435.21 RUS83162.1 - 0 1642.8 345.0 8.2e-23 80.9 6.6 32.1 31 1 1 32 32 32 31 Spectrin repeat CH PF00307.31 RUS83162.1 - 2.6e-45 153.1 0.3 2.2e-23 82.5 0.0 4.7 3 0 0 3 3 3 2 Calponin homology (CH) domain PH_9 PF15410.6 RUS83162.1 - 4.6e-14 52.8 0.0 1.9e-13 50.9 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RUS83162.1 - 5.6e-09 36.5 0.0 2.8e-08 34.2 0.0 2.3 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 RUS83162.1 - 8.8e-07 28.7 0.0 7.3e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RUS83162.1 - 1.9e-06 27.4 0.0 2.8e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_10 PF17902.1 RUS83162.1 - 0.00061 19.8 0.2 0.016 15.3 0.0 2.7 2 0 0 2 2 2 1 SH3 domain CAMSAP_CH PF11971.8 RUS83162.1 - 0.00081 19.2 0.0 0.02 14.7 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain SH3_3 PF08239.11 RUS83162.1 - 0.0076 16.5 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain AntA PF08346.12 RUS83162.1 - 0.059 13.9 6.8 0.17 12.4 0.3 4.5 4 0 0 4 4 4 0 AntA/AntB antirepressor DUF4838 PF16126.5 RUS83162.1 - 0.084 12.2 1.4 2 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) DASH_Dad1 PF08649.10 RUS83162.1 - 5.6 7.2 7.6 36 4.7 0.2 5.3 4 0 0 4 4 4 0 DASH complex subunit Dad1 APC_N_CC PF16689.5 RUS83162.1 - 6.5 6.9 12.2 2.9 8.0 3.3 4.5 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain 7tm_1 PF00001.21 RUS83163.1 - 9.2e-52 176.0 0.5 1.6e-51 175.2 0.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS83163.1 - 6.8e-06 25.6 6.2 6.8e-06 25.6 6.2 2.7 2 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 RUS83163.1 - 3.5e-05 23.3 12.9 0.00039 19.9 8.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS83163.1 - 0.00013 21.7 11.0 0.00013 21.7 11.0 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS83163.1 - 0.00021 21.1 12.3 0.02 14.6 7.0 2.3 2 0 0 2 2 2 2 Olfactory receptor Orf78 PF06024.12 RUS83163.1 - 0.12 12.7 2.8 21 5.5 0.0 3.4 4 0 0 4 4 4 0 Orf78 (ac78) Ig_3 PF13927.6 RUS83164.1 - 1.9e-14 54.0 0.1 1.3e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS83164.1 - 7.9e-13 48.4 0.1 8.7e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS83164.1 - 4.6e-10 39.4 0.0 4.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS83164.1 - 1.9e-09 37.7 0.0 4.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS83164.1 - 0.00013 21.5 0.0 0.43 10.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS83164.1 - 0.00089 19.4 2.1 0.53 10.5 0.2 3.8 2 2 1 3 3 3 1 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS83164.1 - 0.0046 17.3 0.0 3.6 8.1 0.0 2.8 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF4200 PF13863.6 RUS83165.1 - 6.1e-33 113.7 33.0 6.1e-33 113.7 33.0 3.2 2 1 0 3 3 3 3 Domain of unknown function (DUF4200) Glu-tRNAGln PF02686.15 RUS83165.1 - 0.86 9.9 8.7 0.3 11.4 0.3 3.4 3 1 1 4 4 4 0 Glu-tRNAGln amidotransferase C subunit DASH_Dam1 PF08653.10 RUS83165.1 - 6.1 6.7 7.3 12 5.8 0.5 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Histone_H2A_C PF16211.5 RUS83166.1 - 9.1e-21 73.3 0.9 1.8e-20 72.4 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RUS83166.1 - 2.5e-15 57.0 0.0 4.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HTH_psq PF05225.16 RUS83166.1 - 1.8e-06 27.6 0.0 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CBFD_NFYB_HMF PF00808.23 RUS83166.1 - 1.9e-05 24.8 0.0 4.5e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HTH_23 PF13384.6 RUS83166.1 - 0.00075 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 RUS83166.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 RUS83166.1 - 0.045 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Atg8 PF02991.16 RUS83167.1 - 1.2e-48 163.5 0.1 1.5e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RUS83167.1 - 5.1e-07 30.0 0.0 6.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 GFO_IDH_MocA PF01408.22 RUS83168.1 - 2.2e-09 38.2 0.0 4.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 RUS83168.1 - 0.00049 20.7 0.0 0.00096 19.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyco_trans_4_5 PF16994.5 RUS83168.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 UBX PF00789.20 RUS83169.1 - 1.4e-08 34.8 0.0 6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain LRR_8 PF13855.6 RUS83171.1 - 0.00027 20.6 0.1 0.0073 16.1 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat Pentapeptide_4 PF13599.6 RUS83171.1 - 0.16 12.2 1.0 0.79 9.9 0.1 2.5 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_8 PF13855.6 RUS83172.1 - 3.4e-09 36.3 1.3 1e-06 28.4 1.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS83172.1 - 0.00027 21.2 1.0 0.001 19.4 1.0 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS83172.1 - 0.00067 19.6 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS83172.1 - 0.012 16.0 4.1 3.4 8.6 0.1 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat Colipase_C PF02740.14 RUS83172.1 - 0.055 13.7 1.1 2.5 8.4 0.8 2.5 2 0 0 2 2 2 0 Colipase, C-terminal domain TFIID_30kDa PF03540.13 RUS83174.1 - 1.7e-26 91.9 0.0 3.1e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 RUS83174.1 - 0.0043 16.9 0.1 0.0086 15.9 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Bromo_TP PF07524.13 RUS83174.1 - 0.0057 16.6 0.0 0.22 11.5 0.0 2.2 1 1 0 1 1 1 1 Bromodomain associated PALP PF00291.25 RUS83176.1 - 2.2e-64 217.7 0.1 2.5e-64 217.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-H2C2_2 PF13465.6 RUS83177.1 - 1.3e-81 265.6 135.0 7.1e-09 35.7 2.5 21.3 23 0 0 23 23 22 17 Zinc-finger double domain zf-C2H2 PF00096.26 RUS83177.1 - 6.2e-59 193.3 150.2 0.0014 19.0 1.2 20.4 20 0 0 20 20 20 19 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS83177.1 - 6.8e-55 179.0 148.4 0.0028 18.4 0.3 20.5 20 0 0 20 20 20 20 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS83177.1 - 5.6e-25 87.1 87.1 0.12 12.7 0.1 19.0 19 0 0 19 19 19 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS83177.1 - 1.6e-13 50.3 128.0 1e-05 25.4 0.3 19.8 20 0 0 20 20 20 9 C2H2-type zinc finger zf-Di19 PF05605.12 RUS83177.1 - 6.9e-12 45.5 102.0 0.0013 19.0 2.8 11.9 6 3 6 13 13 13 7 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS83177.1 - 7.6e-08 32.5 104.1 0.015 15.7 1.3 18.4 19 0 0 19 19 19 7 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RUS83177.1 - 5.9e-06 25.9 0.4 5.9e-06 25.9 0.4 15.7 19 1 0 19 19 18 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RUS83177.1 - 0.0012 19.2 98.8 1.6 9.1 0.0 15.1 2 1 9 13 13 13 4 C2H2 type zinc-finger (2 copies) zf_Hakai PF18408.1 RUS83177.1 - 0.01 15.5 10.9 12 5.7 0.0 6.1 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain zinc_ribbon_9 PF14369.6 RUS83177.1 - 0.011 16.0 0.6 0.011 16.0 0.6 11.1 13 1 0 13 13 11 0 zinc-ribbon Rpr2 PF04032.16 RUS83177.1 - 0.052 13.8 0.5 0.052 13.8 0.5 9.6 4 2 2 6 6 5 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC_2 PF13913.6 RUS83177.1 - 0.19 11.7 0.1 0.19 11.7 0.1 15.4 17 0 0 17 17 17 0 zinc-finger of a C2HC-type GAGA PF09237.11 RUS83177.1 - 0.51 10.2 34.6 3.2 7.6 0.0 9.5 7 2 3 10 10 9 0 GAGA factor Cys_rich_VLP PF14194.6 RUS83178.1 - 0.2 11.8 4.3 14 5.9 0.0 3.3 4 0 0 4 4 4 0 Cysteine-rich VLP 4HPAD_g_N PF18671.1 RUS83179.1 - 1.1e-08 34.6 24.4 31 4.4 0.0 12.0 13 0 0 13 13 13 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal LEDGF PF11467.8 RUS83179.1 - 9.9e-05 22.0 17.6 1 9.0 0.4 4.8 1 1 6 7 7 7 7 Lens epithelium-derived growth factor (LEDGF) MTBP_mid PF14919.6 RUS83179.1 - 0.00012 21.4 2.1 0.031 13.5 0.4 2.3 1 1 1 2 2 2 2 MDM2-binding putAbiC PF16872.5 RUS83179.1 - 0.025 15.3 0.4 17 6.2 0.0 4.2 1 1 2 4 4 4 0 Putative phage abortive infection protein HTH_39 PF14090.6 RUS83179.1 - 0.08 12.7 7.4 41 4.0 0.0 5.0 1 1 5 6 6 6 0 Helix-turn-helix domain DUF656 PF04920.12 RUS83179.1 - 0.12 12.3 8.3 28 4.7 0.3 3.4 1 1 1 2 2 2 0 Family of unknown function (DUF656) FAM47 PF14642.6 RUS83179.1 - 0.2 11.2 1.3 16 4.9 0.1 2.5 1 1 2 3 3 3 0 FAM47 family Methyltransf_23 PF13489.6 RUS83179.1 - 0.31 10.9 7.3 6.2e+02 0.1 7.3 3.9 1 1 0 1 1 1 0 Methyltransferase domain Lectin_C PF00059.21 RUS83180.1 - 3e-10 40.8 5.5 0.00054 20.7 3.1 3.0 2 1 0 2 2 2 2 Lectin C-type domain Hydrolase PF00702.26 RUS83181.1 - 3.5e-05 24.2 0.0 4.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase C2 PF00168.30 RUS83182.1 - 2.2e-78 259.1 0.1 1.2e-17 64.1 0.0 8.3 7 1 0 7 7 7 6 C2 domain Ferlin_C PF16165.5 RUS83182.1 - 4.3e-34 117.7 12.4 2.8e-30 105.3 0.0 3.4 2 1 1 3 3 3 2 Ferlin C-terminus FerB PF08150.12 RUS83182.1 - 1e-29 102.9 0.3 4.5e-29 100.9 0.0 2.3 2 0 0 2 2 2 1 FerB (NUC096) domain FerI PF08151.12 RUS83182.1 - 1.3e-20 73.2 1.7 2.6e-20 72.2 1.7 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain DNA_pol_phi PF04931.13 RUS83183.1 - 0.00051 18.3 43.3 0.00067 17.9 43.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 RUS83183.1 - 0.0029 16.0 23.2 0.0037 15.6 23.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 RUS83183.1 - 0.018 13.3 32.3 0.024 12.9 32.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS83183.1 - 0.029 13.8 31.5 0.037 13.4 31.5 1.1 1 0 0 1 1 1 0 SDA1 BssB_TutG PF18512.1 RUS83183.1 - 0.2 11.5 3.8 1.1 9.2 0.1 3.1 3 0 0 3 3 3 0 Benzylsuccinate synthase beta subunit DUF2722 PF10846.8 RUS83183.1 - 0.24 10.3 16.5 0.32 9.9 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.15 RUS83183.1 - 0.46 9.2 7.4 0.54 9.0 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 RUS83183.1 - 1.3 8.4 23.4 1.9 7.8 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 RUS83183.1 - 2.6 7.3 28.6 3.4 6.9 28.6 1.1 1 0 0 1 1 1 0 BUD22 Pectate_lyase PF03211.13 RUS83184.1 - 0.002 17.7 0.3 0.0022 17.5 0.3 1.1 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 RUS83185.1 - 5.9e-09 35.3 1.0 6.7e-09 35.1 1.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FTR1 PF03239.14 RUS83185.1 - 0.095 11.9 0.2 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family MFS_1 PF07690.16 RUS83186.1 - 1.6e-14 53.6 14.2 7e-14 51.5 14.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 RUS83186.1 - 0.0054 16.0 10.2 0.0054 16.0 10.2 2.6 1 1 2 3 3 3 1 ZIP Zinc transporter GAGA_bind PF06217.12 RUS83186.1 - 0.019 15.2 13.8 0.024 14.9 13.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SID-1_RNA_chan PF13965.6 RUS83186.1 - 0.034 12.6 6.1 0.06 11.8 6.1 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Drc1-Sld2 PF11719.8 RUS83186.1 - 0.035 13.7 28.0 0.041 13.4 28.0 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein O-antigen_lig PF13425.6 RUS83186.1 - 0.12 11.2 10.6 0.23 10.2 10.6 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CDC45 PF02724.14 RUS83186.1 - 0.13 10.5 33.2 0.17 10.2 33.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RUS83186.1 - 0.21 10.3 19.9 0.015 14.1 14.8 1.8 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 RUS83186.1 - 0.23 11.5 7.2 0.38 10.8 7.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 RUS83186.1 - 0.25 10.3 18.1 1.1 8.2 18.1 2.0 1 1 0 1 1 1 0 CLN3 protein SR-25 PF10500.9 RUS83186.1 - 0.4 10.3 38.3 0.53 9.9 38.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SLC12 PF03522.15 RUS83186.1 - 0.41 9.6 16.4 0.51 9.3 16.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Merozoite_SPAM PF07133.11 RUS83186.1 - 0.43 10.6 53.6 0.56 10.2 53.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 RUS83186.1 - 0.46 9.2 10.3 0.54 9.0 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 RUS83186.1 - 0.51 9.7 25.3 0.77 9.1 25.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 RUS83186.1 - 1.3 7.4 42.8 1.6 7.1 42.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 RUS83186.1 - 1.5 8.1 51.2 1.9 7.8 51.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CCDC106 PF15794.5 RUS83186.1 - 2.5 7.7 29.2 3.8 7.2 29.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ATHILA PF03078.15 RUS83186.1 - 4.9 5.8 21.0 6.1 5.5 21.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Hid1 PF12722.7 RUS83186.1 - 5.8 4.9 15.3 7 4.6 15.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 RUS83186.1 - 7.2 5.5 12.7 12 4.8 12.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Acetyltransf_10 PF13673.7 RUS83187.1 - 5e-09 36.2 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS83187.1 - 1.2e-08 35.2 0.0 3.3e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS83187.1 - 5.8e-08 33.0 0.1 1.2e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 RUS83187.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase PHD PF00628.29 RUS83187.1 - 0.00036 20.4 6.4 0.00093 19.0 6.4 1.8 1 0 0 1 1 1 1 PHD-finger Acetyltransf_9 PF13527.7 RUS83187.1 - 0.00059 19.9 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain C1_1 PF00130.22 RUS83187.1 - 0.0008 19.2 1.0 0.0008 19.2 1.0 2.2 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FR47 PF08445.10 RUS83187.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF1248 PF06852.12 RUS83187.1 - 0.0044 16.5 0.2 4.4 6.7 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1248) PHD_4 PF16866.5 RUS83187.1 - 0.45 10.6 4.2 1.3 9.2 4.2 1.9 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 RUS83187.1 - 0.51 10.7 7.6 0.84 10.0 2.8 2.6 2 0 0 2 2 2 0 C1 domain DOT1 PF08123.13 RUS83189.1 - 1.1e-55 188.3 0.2 1.7e-55 187.7 0.2 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 SPAN-X PF07458.12 RUS83189.1 - 0.016 15.6 1.0 0.027 14.9 1.0 1.3 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome DnaB_2 PF07261.11 RUS83189.1 - 0.035 13.9 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment MRP-S26 PF14943.6 RUS83189.1 - 0.18 11.7 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 SNF2_N PF00176.23 RUS83190.1 - 6.9e-63 212.5 1.0 1.6e-62 211.3 1.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS83190.1 - 5e-18 65.5 0.0 2.1e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS83190.1 - 4.9e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RUS83190.1 - 1.3e-07 31.1 0.1 8.3e-07 28.5 0.1 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 RUS83190.1 - 2.3e-07 31.1 0.2 1.2e-06 28.8 0.1 2.1 2 0 0 2 2 2 1 Rad54 N terminal SWI2_SNF2 PF18766.1 RUS83190.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 RUS83190.1 - 0.054 12.7 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaJ_C PF01556.18 RUS83192.1 - 2.1e-44 151.2 0.1 2.9e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RUS83192.1 - 9.6e-28 96.1 1.9 1.5e-27 95.5 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 RUS83193.1 - 1.4e-33 114.3 15.1 2.6e-07 31.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83193.1 - 2.9e-11 43.5 0.3 0.18 12.1 0.0 5.2 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS83193.1 - 1e-07 32.1 0.0 0.0013 18.7 0.0 3.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RUS83193.1 - 1.2e-05 24.8 2.6 0.0002 20.8 0.3 2.3 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 RUS83193.1 - 0.0025 16.5 1.2 0.089 11.4 0.3 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Laminin_G_2 PF02210.24 RUS83194.1 - 5.9e-77 256.3 2.8 4.2e-26 92.0 0.1 3.5 4 0 0 4 4 4 3 Laminin G domain Laminin_G_1 PF00054.23 RUS83194.1 - 2.4e-74 247.8 0.0 1.3e-26 93.3 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 RUS83194.1 - 5.9e-17 62.2 0.1 3.3e-05 24.1 0.0 3.3 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RUS83194.1 - 1.9e-11 44.0 47.9 0.00018 21.7 5.1 4.8 4 0 0 4 4 4 4 EGF-like domain FXa_inhibition PF14670.6 RUS83194.1 - 1.7e-05 25.0 6.1 1.7e-05 25.0 6.1 4.9 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RUS83194.1 - 2.5e-05 24.8 36.1 0.048 14.3 2.9 5.3 4 0 0 4 4 4 3 Human growth factor-like EGF cEGF PF12662.7 RUS83194.1 - 0.00016 21.5 1.3 0.00016 21.5 1.3 4.7 5 0 0 5 5 5 2 Complement Clr-like EGF-like Mito_fiss_reg PF05308.11 RUS83195.1 - 3.7e-17 63.2 5.1 2.7e-15 57.1 5.1 2.5 1 1 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.19 RUS83195.1 - 2.9 7.3 7.2 0.39 10.2 2.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PDEase_I PF00233.19 RUS83196.1 - 4.2e-08 33.2 0.0 8.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 RUS83197.1 - 1.5e-39 136.1 5.8 2.1e-39 135.7 5.8 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Synapsin PF02078.16 RUS83198.1 - 9.4e-48 160.7 0.0 1.5e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Synapsin, N-terminal domain Synapsin_C PF02750.14 RUS83198.1 - 2.4e-44 151.3 0.1 3.3e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain TPR_1 PF00515.28 RUS83200.1 - 5.8e-15 54.4 2.0 1.7e-05 24.4 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS83200.1 - 5.4e-13 48.0 0.3 9.9e-06 25.3 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS83200.1 - 5.6e-08 32.3 0.0 5.1e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 RUS83200.1 - 1.6e-07 31.0 2.5 0.0081 16.3 0.4 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS83200.1 - 2.1e-07 30.8 0.5 0.25 11.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS83200.1 - 1e-06 28.9 0.2 0.00019 21.7 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS83200.1 - 0.0011 19.6 0.0 0.0095 16.7 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RUS83200.1 - 0.005 16.1 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS83200.1 - 0.011 16.4 0.0 0.028 15.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS83200.1 - 0.014 15.2 0.1 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RUS83200.1 - 0.018 14.1 0.1 0.024 13.7 0.1 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TPR_9 PF13371.6 RUS83200.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat GDPD_2 PF13653.6 RUS83204.1 - 0.00016 22.0 19.9 1.4e+02 3.2 0.0 12.3 14 0 0 14 14 14 0 Glycerophosphoryl diester phosphodiesterase family DNA_pol3_theta PF06440.11 RUS83204.1 - 0.0037 16.9 18.6 9 6.0 0.8 6.0 1 1 9 10 10 10 9 DNA polymerase III, theta subunit RRM_occluded PF16842.5 RUS83204.1 - 0.31 10.9 28.1 22 5.0 1.1 7.5 1 1 7 8 8 8 0 Occluded RNA-recognition motif YdaS_antitoxin PF15943.5 RUS83204.1 - 0.4 10.6 14.0 34 4.4 0.2 5.1 1 1 7 9 9 9 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT XRN1_D2_D3 PF18334.1 RUS83204.1 - 4.3 7.6 15.5 13 6.1 1.1 3.5 1 1 4 5 5 5 0 Exoribonuclease Xrn1 D2/D3 domain Cyclase_polyket PF04673.12 RUS83204.1 - 6.2 7.1 26.8 13 6.1 0.1 6.4 1 1 9 10 10 10 0 Polyketide synthesis cyclase Phage_holin_3_3 PF16083.5 RUS83205.1 - 3.2e-05 23.9 4.2 1.9 8.7 0.1 3.3 2 1 1 3 3 3 3 LydA holin phage, holin superfamily III DUF5021 PF16424.5 RUS83205.1 - 0.0008 19.3 0.2 7.5 6.4 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF5021) DUF5620 PF18522.1 RUS83205.1 - 0.0093 16.4 0.7 32 5.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5620) DUF5060 PF16586.5 RUS83205.1 - 0.02 15.2 0.5 41 4.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5060) CC PF04942.14 RUS83205.1 - 0.041 14.1 0.7 81 3.5 0.0 3.2 3 0 0 3 3 3 0 CC domain Ycf9 PF01737.17 RUS83205.1 - 0.087 12.7 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 YCF9 MASE5 PF17178.4 RUS83205.1 - 0.64 9.8 4.4 9.7 6.0 0.2 2.2 1 1 1 2 2 2 0 Membrane-associated sensor 3HCDH_N PF02737.18 RUS83206.1 - 2.8e-46 157.7 0.0 4.5e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RUS83206.1 - 2.4e-12 47.3 0.0 4.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RUS83206.1 - 7.2e-05 22.4 0.1 0.00011 21.8 0.1 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS83206.1 - 0.00034 20.0 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 RUS83206.1 - 0.0012 19.1 0.0 0.0023 18.1 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 RUS83206.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 RUS83206.1 - 0.0082 15.5 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 RUS83206.1 - 0.013 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS83206.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 RUS83206.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 RUS83206.1 - 0.083 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 RUS83206.1 - 0.19 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF229 PF02995.17 RUS83208.1 - 4.7e-77 259.7 0.2 3.3e-58 197.5 0.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS83208.1 - 0.0067 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 RUS83208.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Tcp10_C PF07202.13 RUS83209.1 - 0.015 15.3 4.2 0.033 14.1 4.2 1.6 1 0 0 1 1 1 0 T-complex protein 10 C-terminus DUF1640 PF07798.11 RUS83209.1 - 0.13 12.3 3.6 0.39 10.7 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ELFV_dehydrog_N PF02812.18 RUS83210.1 - 3.8e-36 123.8 0.0 5.9e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 RUS83210.1 - 2.1e-28 99.7 0.1 1.1e-18 67.8 0.0 3.1 2 1 1 3 3 3 3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyco_hydro_59 PF02057.15 RUS83211.1 - 8.4e-92 307.5 0.1 1.3e-91 306.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 RUS83211.1 - 8.6e-32 109.7 0.3 1.5e-31 108.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Glyco_hydro_30 PF02055.16 RUS83211.1 - 0.0094 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain LSDAT_euk PF18139.1 RUS83212.1 - 2.7e-115 384.3 0.1 4.3e-115 383.7 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 RUS83212.1 - 3.9e-20 72.0 0.1 6.6e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote TRPM_tetra PF16519.5 RUS83212.1 - 2.5e-13 49.9 1.5 2.5e-13 49.9 1.5 2.2 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 RUS83212.1 - 1.8e-12 47.0 19.9 2.8e-12 46.4 19.9 1.2 1 0 0 1 1 1 1 Ion transport protein HlyIII PF03006.20 RUS83212.1 - 0.78 9.4 8.2 1.7 8.3 8.2 1.5 1 0 0 1 1 1 0 Haemolysin-III related XhlA PF10779.9 RUS83212.1 - 1.2 9.4 4.6 1.4 9.2 1.5 2.8 2 1 1 3 3 3 0 Haemolysin XhlA HSBP1 PF06825.12 RUS83212.1 - 2.2 8.2 5.5 15 5.5 0.0 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 7tm_1 PF00001.21 RUS83213.1 - 4e-14 52.6 11.1 5.6e-14 52.1 11.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS83213.1 - 3.3e-07 29.9 2.5 8.2e-07 28.6 2.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw CCB1 PF12046.8 RUS83213.1 - 0.69 9.2 4.7 0.76 9.1 0.6 2.4 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Aminotran_1_2 PF00155.21 RUS83214.1 - 4e-79 266.4 0.0 6e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Actin PF00022.19 RUS83215.1 - 6.6e-141 469.6 0.0 1.9e-140 468.1 0.0 1.6 1 1 0 1 1 1 1 Actin GerD PF17898.1 RUS83215.1 - 0.15 12.0 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain Somatomedin_B PF01033.17 RUS83216.1 - 0.00071 19.9 13.5 0.00071 19.9 13.5 2.7 3 0 0 3 3 3 1 Somatomedin B domain PH PF00169.29 RUS83217.1 - 1.5e-34 118.6 0.7 7e-19 68.3 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 RUS83217.1 - 4.5e-14 52.8 6.9 3e-07 30.8 0.5 5.4 4 2 0 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.6 RUS83217.1 - 5.9e-10 39.3 1.6 0.00099 19.4 0.7 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 RUS83217.1 - 5.2e-08 33.3 0.2 0.0051 17.2 0.0 3.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 RUS83217.1 - 6.2e-07 29.4 0.2 0.0056 16.5 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 RUS83217.1 - 0.00055 20.0 3.4 0.11 12.6 0.2 3.0 3 2 0 3 3 3 2 PH domain Mcp5_PH PF12814.7 RUS83217.1 - 0.0011 19.1 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_6 PF15406.6 RUS83217.1 - 0.0033 17.7 0.0 3.9 7.8 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 RUS83217.1 - 0.005 17.2 0.1 0.4 11.1 0.0 2.6 2 1 0 2 2 2 1 Plant pleckstrin homology-like region PH_16 PF17838.1 RUS83217.1 - 0.041 13.7 0.1 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 PH domain DnaJ PF00226.31 RUS83218.1 - 8.1e-12 45.1 0.1 2e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain CDC45 PF02724.14 RUS83218.1 - 0.027 12.8 21.2 0.033 12.5 21.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 RUS83218.1 - 0.19 10.1 7.2 0.31 9.4 7.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_polI_A34 PF08208.11 RUS83218.1 - 0.72 9.9 25.0 1.4 9.0 25.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2746 PF10874.8 RUS83218.1 - 1.7 9.1 7.3 0.44 11.0 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) LMBR1 PF04791.16 RUS83218.1 - 2.3 7.0 12.5 3.1 6.6 12.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 RUS83218.1 - 4.4 6.0 17.7 6 5.5 17.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 RUS83218.1 - 5.7 6.2 10.4 6.8 5.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PT PF04886.12 RUS83219.1 - 3e-82 269.8 265.5 1.8e+04 -173.4 265.5 8.3 1 1 0 1 1 1 0 PT repeat PQ-loop PF04193.14 RUS83220.1 - 6.3e-15 54.7 0.1 6.3e-15 54.7 0.1 2.2 2 0 0 2 2 2 1 PQ loop repeat FAM217 PF15344.6 RUS83222.1 - 0.0037 17.2 4.4 0.0037 17.2 4.4 3.3 2 1 0 2 2 2 1 FAM217 family TFIIA PF03153.13 RUS83222.1 - 0.018 15.1 1.5 0.028 14.4 1.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Choline_kinase PF01633.20 RUS83224.1 - 1.3e-33 116.4 0.0 7.5e-24 84.5 0.0 2.3 1 1 1 2 2 2 2 Choline/ethanolamine kinase Sulfatase PF00884.23 RUS83225.1 - 9.2e-74 248.6 0.2 1.2e-73 248.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS83225.1 - 3.2e-09 36.9 0.1 4.6e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 RUS83225.1 - 0.0051 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphoesterase PF04185.14 RUS83225.1 - 0.15 11.2 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoesterase family Prolactin_RP PF15172.6 RUS83226.1 - 0.16 11.7 0.7 0.27 10.9 0.7 1.3 1 0 0 1 1 1 0 Prolactin-releasing peptide DNA_pol_phi PF04931.13 RUS83226.1 - 1.6 6.8 106.0 1.2 7.2 46.8 2.4 2 0 0 2 2 2 0 DNA polymerase phi Lectin_C PF00059.21 RUS83227.1 - 8.7e-14 52.2 0.4 5.2e-08 33.6 0.5 2.3 2 0 0 2 2 2 2 Lectin C-type domain IgGFc_binding PF17517.2 RUS83227.1 - 1.6e-10 40.8 0.2 2.7e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 IgGFc binding protein Xlink PF00193.17 RUS83227.1 - 0.097 13.1 0.4 13 6.2 0.1 2.7 3 0 0 3 3 3 0 Extracellular link domain Peptidase_M64 PF09471.10 RUS83227.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 ATG22 PF11700.8 RUS83228.1 - 0.0091 14.7 0.2 0.01 14.5 0.2 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Macoilin PF09726.9 RUS83230.1 - 5.7 5.4 9.4 7.9 4.9 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Pentapeptide PF00805.22 RUS83232.1 - 5.2e-10 38.8 62.0 0.081 12.6 2.2 8.7 6 2 2 8 8 8 8 Pentapeptide repeats (8 copies) MTP18 PF10558.9 RUS83233.1 - 0.034 14.1 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Lipoprotein_21 PF14041.6 RUS83234.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 LppP/LprE lipoprotein Sushi PF00084.20 RUS83236.1 - 1.9e-08 34.7 0.2 3.1e-08 34.1 0.2 1.4 1 1 0 1 1 1 1 Sushi repeat (SCR repeat) HRM PF02793.22 RUS83236.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Hormone receptor domain Aldo_ket_red PF00248.21 RUS83237.1 - 1.3e-73 247.8 0.0 1.5e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAM167 PF11652.8 RUS83239.1 - 3.2e-28 98.0 0.4 8.2e-28 96.7 0.4 1.8 1 0 0 1 1 1 1 FAM167 LURAP PF14854.6 RUS83239.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.1 3 0 0 3 3 3 0 Leucine rich adaptor protein Med9 PF07544.13 RUS83239.1 - 0.26 11.4 3.3 1 9.5 3.3 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2388 PF09498.10 RUS83239.1 - 0.7 9.9 2.3 1.3 9.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF4404 PF14357.6 RUS83239.1 - 2.4 8.9 6.7 7.2 7.3 6.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4530 PF15039.6 RUS83239.1 - 4.1 7.6 7.9 0.35 11.0 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Peptidase_M14 PF00246.24 RUS83240.1 - 2.6e-27 96.4 0.0 1.2e-19 71.3 0.0 3.0 1 1 1 2 2 2 2 Zinc carboxypeptidase NOA36 PF06524.12 RUS83240.1 - 0.021 14.2 20.0 0.031 13.6 20.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 RUS83240.1 - 0.51 9.2 2.3 0.61 9.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.12 RUS83240.1 - 0.56 9.9 21.6 0.85 9.3 21.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 RUS83240.1 - 0.77 8.8 27.4 1 8.4 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 RUS83240.1 - 9.7 5.7 11.9 15 5.0 11.9 1.2 1 0 0 1 1 1 0 PPP4R2 Auts2 PF15336.6 RUS83242.1 - 3.5e-07 30.6 0.2 3.5e-07 30.6 0.2 3.0 2 1 1 3 3 3 1 Autism susceptibility gene 2 protein GHMP_kinases_N PF00288.26 RUS83242.1 - 0.063 13.5 0.4 0.063 13.5 0.4 2.0 2 0 0 2 2 2 0 GHMP kinases N terminal domain SelP_N PF04592.14 RUS83242.1 - 10 5.5 15.6 0.47 9.8 7.4 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Rrn6 PF10214.9 RUS83243.1 - 1.1 7.7 5.9 1.2 7.5 5.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Consortin_C PF15281.6 RUS83244.1 - 0.0019 18.2 0.1 0.0022 18.0 0.1 1.1 1 0 0 1 1 1 1 Consortin C-terminus Ribosomal_60s PF00428.19 RUS83245.1 - 1.8e-27 95.7 7.7 2.4e-27 95.3 7.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein IBR PF01485.21 RUS83246.1 - 1.8e-10 40.8 25.7 4.5e-07 30.0 9.1 5.5 5 1 1 6 6 6 3 IBR domain, a half RING-finger domain PI3_PI4_kinase PF00454.27 RUS83247.1 - 1.4e-35 123.3 0.2 1.2e-32 113.7 0.2 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 RUS83247.1 - 0.088 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) SelP_N PF04592.14 RUS83247.1 - 1.8 7.9 11.1 3.5 7.0 11.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DS PF01916.17 RUS83248.1 - 3.4e-46 157.8 0.1 3.8e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase STELLO PF03385.17 RUS83249.1 - 2.6e-07 29.8 1.3 1.2e-05 24.3 0.6 2.1 2 0 0 2 2 2 2 STELLO glycosyltransferases CYTL1 PF15153.6 RUS83249.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Cytokine-like protein 1 ERbeta_N PF12497.8 RUS83250.1 - 0.042 13.6 0.4 11 5.9 0.0 3.5 3 0 0 3 3 3 0 Estrogen receptor beta Tex_YqgF PF16921.5 RUS83250.1 - 0.13 12.7 6.1 0.29 11.6 0.4 2.4 1 1 1 2 2 2 0 Tex protein YqgF-like domain Spectrin PF00435.21 RUS83250.1 - 0.22 12.0 3.0 0.25 11.8 2.0 1.6 1 1 0 1 1 1 0 Spectrin repeat DUF2616 PF11077.8 RUS83250.1 - 0.61 9.8 26.6 1.4 8.7 0.7 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2616) UPAR_LY6_2 PF16975.5 RUS83251.1 - 5.7e-06 26.5 28.0 0.0063 16.7 11.6 3.1 2 1 0 2 2 2 2 Ly6/PLAUR domain-containing protein 6, Lypd6 Lectin_C PF00059.21 RUS83253.1 - 6.1e-12 46.2 0.0 1.5e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain DUF4795 PF16043.5 RUS83253.1 - 0.00066 19.3 1.0 0.0011 18.6 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 RUS83253.1 - 0.00087 19.2 0.1 0.0013 18.6 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PTRF_SDPR PF15237.6 RUS83253.1 - 0.0024 17.5 0.4 0.0042 16.8 0.4 1.3 1 0 0 1 1 1 1 PTRF/SDPR family Fib_alpha PF08702.10 RUS83253.1 - 0.0082 16.3 1.5 0.015 15.5 1.5 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 RUS83253.1 - 0.013 15.9 1.4 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 RUS83253.1 - 0.025 14.6 8.3 0.1 12.6 3.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 RUS83253.1 - 0.031 14.5 1.3 0.11 12.8 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2884 PF11101.8 RUS83253.1 - 0.037 13.5 1.2 0.061 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RmuC PF02646.16 RUS83253.1 - 0.038 13.1 0.7 0.76 8.8 0.1 2.1 1 1 1 2 2 2 0 RmuC family Interferon PF00143.19 RUS83253.1 - 0.05 13.8 1.6 0.08 13.1 1.6 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Mis12 PF05859.12 RUS83253.1 - 0.056 13.5 0.4 0.1 12.7 0.4 1.5 1 0 0 1 1 1 0 Mis12 protein HsbA PF12296.8 RUS83253.1 - 0.089 13.2 0.5 0.25 11.8 0.3 1.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Not3 PF04065.15 RUS83253.1 - 0.16 11.4 1.0 2.6 7.4 0.2 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component WXG100 PF06013.12 RUS83253.1 - 0.16 12.2 2.9 2.9 8.2 1.0 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.9 RUS83253.1 - 0.2 11.7 1.3 0.36 10.8 1.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 RUS83253.1 - 0.24 11.4 3.5 0.28 11.2 0.9 2.1 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 RUS83253.1 - 0.37 11.1 2.7 5.5 7.4 1.0 2.5 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1043 PF06295.12 RUS83253.1 - 0.61 10.1 3.3 0.92 9.5 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Sigma70_r3 PF04539.16 RUS83254.1 - 7e-05 22.8 3.8 1.1 9.4 0.0 5.7 3 1 2 5 5 5 2 Sigma-70 region 3 PgaD PF13994.6 RUS83254.1 - 0.019 15.0 6.5 28 4.8 0.0 5.8 3 2 4 7 7 7 0 PgaD-like protein CPSase_L_D3 PF02787.19 RUS83254.1 - 0.047 14.0 7.1 20 5.6 0.5 5.3 2 2 2 4 4 4 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MerR-DNA-bind PF09278.11 RUS83254.1 - 0.053 14.1 0.0 46 4.7 0.0 4.2 4 0 0 4 4 4 0 MerR, DNA binding Put_DNA-bind_N PF06971.13 RUS83254.1 - 0.06 13.4 0.5 26 4.9 0.0 4.4 4 0 0 4 4 4 0 Putative DNA-binding protein N-terminus Mrr_N PF14338.6 RUS83254.1 - 0.13 12.4 9.0 13 6.0 0.3 6.0 5 1 2 7 7 7 0 Mrr N-terminal domain SinI PF08671.10 RUS83254.1 - 0.14 12.0 4.9 8.6 6.2 0.0 5.0 6 0 0 6 6 6 0 Anti-repressor SinI GrpE PF01025.19 RUS83254.1 - 0.28 10.8 2.0 1.6 8.3 0.6 2.5 1 1 1 2 2 2 0 GrpE Homeodomain PF00046.29 RUS83254.1 - 1.2 9.0 4.4 1.1e+02 2.8 0.0 5.2 8 0 0 8 8 8 0 Homeodomain BNIP2 PF12496.8 RUS83254.1 - 3.7 8.0 10.9 17 5.9 7.1 3.3 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pyridoxal_deC PF00282.19 RUS83255.1 - 1.7e-80 270.6 0.0 2.1e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain QVR PF17064.5 RUS83256.1 - 0.31 11.3 49.6 0.17 12.2 4.1 5.8 5 1 0 5 5 5 0 Sleepless protein CFC PF09443.10 RUS83257.1 - 0.68 9.8 14.4 6.1 6.8 0.5 3.5 2 1 2 4 4 4 0 Cripto_Frl-1_Cryptic (CFC) EF-hand_7 PF13499.6 RUS83259.1 - 3.5e-23 81.8 6.4 3.3e-16 59.5 0.9 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RUS83259.1 - 1.9e-21 73.9 12.9 5.8e-08 31.7 0.2 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS83259.1 - 2.2e-19 67.6 8.6 6.1e-06 25.8 0.3 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RUS83259.1 - 7.4e-14 50.5 10.3 1.7e-05 24.1 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS83259.1 - 2.1e-11 43.5 11.7 1.9e-05 24.4 1.0 3.9 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS83259.1 - 0.00014 22.1 3.5 0.054 13.8 0.6 3.5 1 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS83259.1 - 0.00096 19.1 3.9 1.5 8.8 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RUS83259.1 - 0.02 15.2 0.2 1.6 9.1 0.0 3.3 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 RUS83259.1 - 0.052 13.5 3.6 9.3 6.1 0.1 3.0 1 1 0 2 2 2 0 Caleosin related protein S10_plectin PF03501.15 RUS83259.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain SHIPPO-rpt PF07004.12 RUS83260.1 - 0.034 15.1 1.5 0.13 13.2 1.5 2.1 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat UBA PF00627.31 RUS83261.1 - 1.2e-16 60.2 0.2 1.1e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain STI1 PF17830.1 RUS83261.1 - 0.096 12.6 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 STI1 domain DUF3173 PF11372.8 RUS83261.1 - 0.19 11.6 0.1 13 5.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3173) RNase_T PF00929.24 RUS83262.1 - 2e-12 48.0 0.0 2.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 RUS83262.1 - 0.00028 20.9 0.0 0.0055 16.7 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 RUS83262.1 - 0.058 12.5 0.0 0.43 9.7 0.0 2.0 1 1 1 2 2 2 0 DNA polymerase family B, exonuclease domain TED_complement PF07678.14 RUS83263.1 - 8e-45 153.2 0.3 1.2e-44 152.7 0.3 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 RUS83263.1 - 8.1e-24 83.3 0.0 4.6e-23 80.9 0.0 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG2 PF01835.19 RUS83263.1 - 5.9e-16 58.7 0.1 1.8e-14 53.9 0.1 3.2 2 0 0 2 2 2 1 MG2 domain A2M_recep PF07677.14 RUS83263.1 - 1.5e-12 48.1 0.0 5.3e-12 46.3 0.0 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 RUS83263.1 - 6.7e-11 42.7 0.6 7.7e-09 36.0 0.0 3.7 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 RUS83263.1 - 3e-08 33.8 0.0 2.1e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 RUS83263.1 - 1e-07 32.0 0.2 1e-07 32.0 0.2 3.9 4 1 1 5 5 5 1 Macroglobulin domain MG4 NTR PF01759.21 RUS83263.1 - 0.00027 20.7 0.1 0.00073 19.3 0.1 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module BAT2_N PF07001.11 RUS83264.1 - 1.5e-40 139.7 6.8 2.3e-40 139.1 6.8 1.3 1 0 0 1 1 1 1 BAT2 N-terminus Hydrolase_6 PF13344.6 RUS83265.1 - 2.5e-17 62.8 0.0 4.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS83265.1 - 8.7e-07 28.9 0.0 0.00028 20.9 0.0 2.8 3 0 0 3 3 3 2 HAD-hyrolase-like zf-C2H2 PF00096.26 RUS83266.1 - 5.8e-20 70.6 31.1 5.8e-06 26.5 4.2 5.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS83266.1 - 3.8e-16 58.7 27.4 3.4e-07 30.4 0.1 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS83266.1 - 9.4e-08 31.9 17.6 0.0027 17.7 0.1 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS83266.1 - 2.1e-05 25.0 15.7 0.0031 18.2 2.4 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS83266.1 - 8.2e-05 22.3 5.6 0.21 11.4 0.0 3.9 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RUS83266.1 - 8.3e-05 22.3 3.5 8.3e-05 22.3 3.5 3.9 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-LYAR PF08790.11 RUS83266.1 - 0.023 14.6 2.0 0.12 12.2 0.6 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 RUS83266.1 - 0.24 12.2 4.7 6.4 7.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 RUS83266.1 - 9.3 6.5 11.1 0.93 9.7 3.9 2.8 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 RUS83266.1 - 9.7 6.3 7.9 1.7e+02 2.3 0.0 3.1 2 1 0 2 2 2 0 Double zinc ribbon Dimer_Tnp_hAT PF05699.14 RUS83267.1 - 0.0033 17.2 0.4 0.01 15.6 0.4 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GCV_H PF01597.19 RUS83268.1 - 1.5e-05 24.9 0.0 6.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage H-protein Ig_3 PF13927.6 RUS83269.1 - 1.3e-16 60.9 0.2 4e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS83269.1 - 7e-16 58.2 2.0 6.1e-07 29.5 0.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS83269.1 - 8.1e-16 57.9 0.2 5.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RUS83269.1 - 1.1e-12 48.1 1.0 1.1e-06 28.7 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS83269.1 - 1e-08 35.4 0.1 0.007 16.7 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS83269.1 - 0.001 18.6 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 RUS83269.1 - 0.0014 18.8 0.0 12 6.2 0.0 3.5 2 1 1 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS83269.1 - 0.042 13.9 0.1 2.6 8.2 0.1 2.6 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain zf-RING_UBOX PF13445.6 RUS83272.1 - 9e-09 35.2 6.5 9e-09 35.2 6.5 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS83272.1 - 1.4e-08 34.4 5.5 1.4e-08 34.4 5.5 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS83272.1 - 1.7e-08 34.5 6.1 1.7e-08 34.5 6.1 3.1 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RUS83272.1 - 1.8e-07 30.9 9.0 1.8e-07 30.9 9.0 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS83272.1 - 3.4e-06 27.3 9.6 3.4e-06 27.3 9.6 2.9 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS83272.1 - 4.8e-05 23.1 6.5 4.8e-05 23.1 6.5 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS83272.1 - 6.7e-05 22.8 9.7 6.7e-05 22.8 9.7 2.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-B_box PF00643.24 RUS83272.1 - 0.00065 19.8 8.5 0.00065 19.8 8.5 2.8 2 1 0 2 2 2 1 B-box zinc finger Apolipoprotein PF01442.18 RUS83272.1 - 0.0031 17.4 1.1 0.0056 16.6 1.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain OMS28_porin PF03532.13 RUS83272.1 - 0.039 13.2 0.7 0.088 12.0 0.6 1.5 1 1 0 1 1 1 0 OMS28 porin LMP PF04778.12 RUS83272.1 - 0.051 13.5 1.8 0.12 12.3 1.8 1.5 1 0 0 1 1 1 0 LMP repeated region zf-WRNIP1_ubi PF18279.1 RUS83272.1 - 0.064 13.9 0.1 1.3 9.8 0.0 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain PIN_8 PF18476.1 RUS83272.1 - 0.096 12.5 1.3 0.17 11.7 1.3 1.3 1 0 0 1 1 1 0 PIN like domain GrpE PF01025.19 RUS83272.1 - 0.15 11.7 4.0 0.27 10.9 4.0 1.3 1 0 0 1 1 1 0 GrpE zf-Nse PF11789.8 RUS83272.1 - 0.28 11.0 5.2 0.6 10.0 5.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RUS83272.1 - 1.1 9.2 15.2 0.33 10.9 6.1 3.5 3 1 0 3 3 3 0 zf-RING of BARD1-type protein EF-hand_6 PF13405.6 RUS83274.1 - 2.5e-13 48.8 2.5 5.6e-07 29.0 0.5 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS83274.1 - 8.5e-12 45.4 0.2 9e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS83274.1 - 8.5e-11 40.6 8.3 6.7e-06 25.3 1.3 3.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 RUS83274.1 - 3.7e-05 23.0 3.9 0.00033 20.0 1.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 RUS83274.1 - 0.00011 22.4 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS83274.1 - 0.013 15.4 3.0 0.25 11.2 0.0 3.5 2 2 2 4 4 4 0 EF-hand domain pair EFhand_Ca_insen PF08726.10 RUS83274.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.13 RUS83274.1 - 0.041 13.9 0.0 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LXG PF04740.12 RUS83274.1 - 0.081 12.6 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily DDE_Tnp_IS66_C PF13817.6 RUS83274.1 - 0.17 12.1 0.0 0.68 10.2 0.0 2.0 3 0 0 3 3 3 0 IS66 C-terminal element ABC_membrane PF00664.23 RUS83275.1 - 1.1e-123 412.3 26.1 3.8e-63 213.7 7.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS83275.1 - 1.4e-74 249.1 0.1 6.3e-38 130.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS83275.1 - 4.5e-16 59.0 1.4 6.9e-07 28.9 0.1 3.8 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS83275.1 - 5.3e-11 42.9 0.5 0.0003 21.1 0.0 3.5 3 2 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 RUS83275.1 - 1.2e-09 37.5 0.5 0.00032 19.6 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 RUS83275.1 - 2.5e-08 34.5 0.9 0.0037 17.7 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RUS83275.1 - 1.1e-06 28.7 0.0 0.065 13.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 RUS83275.1 - 2.7e-06 27.4 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 RUS83275.1 - 9.1e-06 25.7 0.1 0.37 10.8 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 RUS83275.1 - 9.8e-06 25.9 0.3 0.49 10.6 0.2 3.5 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 RUS83275.1 - 1.8e-05 25.3 0.0 0.34 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RUS83275.1 - 6.5e-05 22.6 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RUS83275.1 - 0.00019 21.4 0.0 0.26 11.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 RUS83275.1 - 0.00022 21.6 8.9 0.78 10.2 0.5 5.3 4 2 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 RUS83275.1 - 0.0003 20.6 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 RUS83275.1 - 0.00045 20.0 2.8 0.53 10.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 RUS83275.1 - 0.00049 19.8 0.0 0.081 12.6 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 RUS83275.1 - 0.00058 19.4 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 RUS83275.1 - 0.00073 19.9 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 RUS83275.1 - 0.001 18.8 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 RUS83275.1 - 0.0011 19.2 4.4 2 8.7 0.4 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 RUS83275.1 - 0.0014 17.8 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 RUS83275.1 - 0.0015 18.7 0.0 3.1 7.8 0.0 2.8 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_25 PF13481.6 RUS83275.1 - 0.0015 18.1 0.1 1.2 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RUS83275.1 - 0.0024 18.1 0.6 4.2 7.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF2852 PF11014.8 RUS83275.1 - 0.0025 18.0 1.6 1.6 8.9 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2852) Zeta_toxin PF06414.12 RUS83275.1 - 0.0036 16.6 2.5 0.3 10.3 0.0 3.4 4 0 0 4 4 4 1 Zeta toxin DUF815 PF05673.13 RUS83275.1 - 0.0065 15.7 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PRK PF00485.18 RUS83275.1 - 0.01 15.6 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 RUS83275.1 - 0.012 15.5 0.3 6.1 6.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.6 RUS83275.1 - 0.017 15.2 0.0 23 5.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 RUS83275.1 - 0.017 14.9 0.0 3.8 7.2 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RUS83275.1 - 0.025 13.8 0.0 6 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 RUS83275.1 - 0.029 14.1 0.4 12 5.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RUS83275.1 - 0.036 13.4 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 RUS83275.1 - 0.044 13.9 0.0 0.97 9.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 RUS83275.1 - 0.046 14.2 0.2 20 5.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RUS83275.1 - 0.052 13.6 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 RUS83275.1 - 0.069 13.7 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RUS83277.1 - 3e-37 128.0 0.0 5.2e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS83277.1 - 6.9e-10 38.6 0.0 2.2e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 RUS83277.1 - 4.8e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LisH PF08513.11 RUS83277.1 - 0.00035 20.4 0.5 0.00072 19.4 0.5 1.6 1 0 0 1 1 1 1 LisH AAA_16 PF13191.6 RUS83277.1 - 0.00043 20.7 0.0 0.00095 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 RUS83277.1 - 0.00065 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 RUS83277.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS83277.1 - 0.0024 18.2 0.1 0.0077 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RUS83277.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RUS83277.1 - 0.0093 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS83277.1 - 0.0098 16.3 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 RUS83277.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 RUS83277.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 RUS83277.1 - 0.026 15.1 0.1 0.09 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RUS83277.1 - 0.036 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RUS83277.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RUS83277.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 RUS83277.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RUS83277.1 - 0.077 12.4 0.1 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 RUS83277.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PPTA PF01239.22 RUS83278.1 - 4.1e-25 86.7 13.9 7.1e-08 31.9 1.3 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat COMM_domain PF07258.14 RUS83279.1 - 1.8e-16 60.0 0.0 3.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 COMM domain zf-CDGSH PF09360.10 RUS83280.1 - 2e-20 72.7 4.5 1.3e-09 38.1 0.7 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Arm PF00514.23 RUS83281.1 - 3.2e-39 131.8 26.1 1.7e-08 34.2 0.0 9.1 10 0 0 10 10 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS83281.1 - 5.8e-15 55.5 16.4 0.0017 18.7 0.6 5.9 2 2 4 6 6 6 5 HEAT repeats Cnd1 PF12717.7 RUS83281.1 - 6.9e-13 49.0 2.4 0.012 15.7 0.4 5.1 2 2 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RUS83281.1 - 1.5e-12 46.7 16.2 0.0057 16.8 0.0 8.4 9 0 0 9 9 8 3 HEAT repeat DNA_alkylation PF08713.11 RUS83281.1 - 7.7e-09 35.6 0.3 0.21 11.3 0.0 4.1 2 1 1 4 4 4 3 DNA alkylation repair enzyme HEAT_EZ PF13513.6 RUS83281.1 - 2.5e-08 34.3 20.8 0.0055 17.2 1.0 6.8 4 2 4 8 8 7 3 HEAT-like repeat Adaptin_N PF01602.20 RUS83281.1 - 1.7e-07 30.2 7.7 0.013 14.1 1.7 4.6 2 1 2 4 4 4 3 Adaptin N terminal region CHASE6_C PF17150.4 RUS83281.1 - 2.8e-07 31.1 2.8 7.5 7.3 0.0 6.8 6 1 1 7 7 7 0 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 RUS83281.1 - 2.2e-05 23.2 4.8 0.00048 18.8 0.4 3.0 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 RUS83281.1 - 0.00038 20.6 0.4 0.095 12.9 0.2 3.2 3 1 0 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_V PF14668.6 RUS83281.1 - 0.00066 19.9 0.2 2.9 8.2 0.0 4.3 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 API5 PF05918.11 RUS83281.1 - 0.0008 18.3 11.8 0.045 12.6 1.4 3.9 3 1 1 4 4 4 3 Apoptosis inhibitory protein 5 (API5) HEAT_PBS PF03130.16 RUS83281.1 - 0.0018 18.8 11.6 0.14 12.9 0.3 5.4 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 RUS83281.1 - 0.0023 17.5 0.5 2 7.9 0.1 3.2 2 1 1 3 3 3 1 CLASP N terminal V-ATPase_H_C PF11698.8 RUS83281.1 - 0.0033 17.5 3.3 1.5 8.9 0.2 4.0 4 0 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 RUS83281.1 - 0.0039 16.6 0.5 0.5 9.7 0.2 2.7 1 1 1 2 2 2 1 Mo25-like RICTOR_N PF14664.6 RUS83281.1 - 0.0052 15.8 6.3 0.17 10.9 1.2 3.8 1 1 2 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term MMS22L_C PF14911.6 RUS83281.1 - 0.014 14.5 0.4 1.8 7.6 0.1 2.7 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal DUF3361 PF11841.8 RUS83281.1 - 0.014 15.3 0.8 0.29 11.1 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) MMS19_C PF12460.8 RUS83281.1 - 0.016 14.3 4.4 1.2 8.2 0.4 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal CelTOS PF18659.1 RUS83281.1 - 0.034 14.6 2.3 9.6 6.7 0.2 3.2 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DUF3731 PF12531.8 RUS83281.1 - 0.04 13.7 7.9 1.2 8.9 0.4 3.4 2 1 1 4 4 4 0 DNA-K related protein Cobalamin_bind PF01122.19 RUS83281.1 - 0.36 9.7 3.2 0.31 9.9 0.6 2.0 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein XPC-binding PF09280.11 RUS83281.1 - 2.3 8.0 6.1 11 5.8 0.0 5.0 7 0 0 7 7 7 0 XPC-binding domain U3snoRNP10 PF12397.8 RUS83281.1 - 4.1 7.8 6.5 2.7 8.3 0.7 3.3 2 2 1 4 4 4 0 U3 small nucleolar RNA-associated protein 10 PMP22_Claudin PF00822.20 RUS83282.1 - 1.3e-05 25.1 1.4 2e-05 24.5 1.4 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS83282.1 - 0.032 14.0 0.3 0.084 12.6 0.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Scramblase PF03803.15 RUS83283.1 - 4.9e-50 169.9 0.1 6e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 Scramblase DSPc PF00782.20 RUS83284.1 - 1e-40 138.6 0.1 1.6e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS83284.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 RUS83284.1 - 4.7e-05 23.9 0.0 0.00098 19.6 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Init_tRNA_PT PF04179.12 RUS83284.1 - 0.0071 16.6 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 RUS83284.1 - 0.091 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF5575 PF17738.1 RUS83285.1 - 0.0038 16.3 0.5 0.34 9.9 0.0 2.8 3 0 0 3 3 3 2 Family of unknown function (DUF5575) FAR1 PF03101.15 RUS83285.1 - 0.019 15.6 1.3 0.036 14.8 0.4 2.1 2 0 0 2 2 2 0 FAR1 DNA-binding domain SWIM PF04434.17 RUS83285.1 - 0.069 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 SWIM zinc finger DUF4108 PF13390.6 RUS83285.1 - 0.079 12.9 1.3 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) MFS_1 PF07690.16 RUS83286.1 - 6.7e-26 91.0 19.1 6.6e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI5 PF06330.11 RUS83286.1 - 0.036 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Hormone_recep PF00104.30 RUS83289.1 - 9.6e-39 133.1 0.0 1.8e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS83289.1 - 3e-31 107.7 16.8 5.2e-31 106.9 16.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Tubulin_C PF03953.17 RUS83289.1 - 0.054 13.7 0.4 0.67 10.1 0.2 2.2 2 0 0 2 2 2 0 Tubulin C-terminal domain Glyco_transf_10 PF00852.19 RUS83290.1 - 9.6e-47 159.0 3.9 1.3e-46 158.5 3.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS83290.1 - 1.8e-14 54.1 1.5 2.7e-14 53.6 0.1 2.0 3 0 0 3 3 3 1 Fucosyltransferase, N-terminal Collagen PF01391.18 RUS83291.1 - 7.4 6.4 9.4 24 4.8 3.0 2.6 1 1 1 2 2 2 0 Collagen triple helix repeat (20 copies) G-alpha PF00503.20 RUS83292.1 - 2.7e-23 82.7 1.4 3e-23 82.6 1.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit UPF0489 PF12640.7 RUS83293.1 - 0.053 13.7 0.0 0.65 10.2 0.0 2.2 2 0 0 2 2 2 0 UPF0489 domain Endomucin PF07010.12 RUS83293.1 - 1.9 8.4 19.4 0.39 10.7 15.8 1.7 2 0 0 2 2 2 0 Endomucin NIF PF03031.18 RUS83294.1 - 1.2e-27 96.7 0.3 2.2e-27 95.7 0.3 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 RUS83294.1 - 7.1e-06 25.7 0.3 2.6e-05 23.9 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 RUS83294.1 - 0.066 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Endosulfine PF04667.17 RUS83295.1 - 5.8e-12 45.6 1.6 7.1e-12 45.3 1.1 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MAS20 PF02064.15 RUS83295.1 - 0.014 15.4 1.3 0.018 15.1 1.3 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Pkinase PF00069.25 RUS83296.1 - 1.8e-42 145.5 0.0 2.4e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83296.1 - 3.8e-41 141.1 0.0 5.2e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RUS83296.1 - 0.0092 15.6 0.1 0.024 14.3 0.1 1.7 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 RUS83296.1 - 0.089 12.4 0.1 8.7 5.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FA_desaturase PF00487.24 RUS83297.1 - 4.6e-13 49.6 19.0 6.8e-13 49.0 19.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase LicD PF04991.13 RUS83298.1 - 1.4e-11 45.0 1.4 1.7e-07 31.6 2.6 2.2 1 1 1 2 2 2 2 LicD family LicD PF04991.13 RUS83299.1 - 4.2e-11 43.4 1.5 3.3e-07 30.7 2.7 2.2 1 1 0 2 2 2 2 LicD family SWIB PF02201.18 RUS83300.1 - 3.1e-22 78.2 0.3 7.3e-22 77.1 0.3 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain CAF1C_H4-bd PF12265.8 RUS83301.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_hydro_10 PF00331.20 RUS83302.1 - 1.3e-23 83.7 1.2 1.7e-23 83.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PCSK9_C3 PF18463.1 RUS83302.1 - 0.17 12.2 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain RVT_1 PF00078.27 RUS83303.1 - 9.6e-23 80.9 0.1 1.4e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 RUS83304.1 - 4.7e-24 85.0 33.3 1.6e-17 63.5 14.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS83304.1 - 3e-06 26.0 23.0 8.8e-05 21.2 8.8 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 RUS83304.1 - 4.7e-06 25.7 7.4 0.0021 17.0 0.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_10 PF00331.20 RUS83305.1 - 2e-36 125.8 0.5 3e-36 125.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 RUS83305.1 - 8.6e-10 39.0 0.0 1.9e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain PCSK9_C1 PF18459.1 RUS83305.1 - 3.8e-08 33.4 11.5 2.7e-07 30.6 1.3 3.2 1 1 2 3 3 3 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C3 PF18463.1 RUS83305.1 - 9.5e-06 25.8 14.4 0.0006 20.0 3.3 2.7 1 1 1 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain PCSK9_C2 PF18464.1 RUS83305.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.5 3 1 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Ig_3 PF13927.6 RUS83306.1 - 2.8e-10 40.6 0.0 6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS83306.1 - 5.7e-10 39.1 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 RUS83306.1 - 1.5e-07 31.6 0.0 0.00038 20.6 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS83306.1 - 6.1e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS83306.1 - 7.4e-07 29.3 0.0 1.8e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 RUS83306.1 - 0.0088 16.4 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS83306.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain C2-set PF05790.15 RUS83306.1 - 0.026 14.7 0.2 0.051 13.8 0.2 1.4 1 0 0 1 1 1 0 Immunoglobulin C2-set domain Ig_4 PF16680.5 RUS83306.1 - 0.07 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Pkinase_Tyr PF07714.17 RUS83307.1 - 1.4e-91 306.4 0.0 1.8e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS83307.1 - 1.5e-40 139.3 0.0 4.3e-39 134.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain I-set PF07679.16 RUS83307.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Shisa PF13908.6 RUS83307.1 - 0.0055 17.0 0.0 0.009 16.3 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ig PF00047.25 RUS83307.1 - 0.0055 16.9 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kinase-like PF14531.6 RUS83307.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RUS83307.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Comm PF15957.5 RUS83307.1 - 0.026 14.9 0.1 0.05 14.0 0.1 1.4 1 0 0 1 1 1 0 Commissureless DAG1 PF05454.11 RUS83307.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 RUS83307.1 - 0.044 14.7 0.0 0.098 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.10 RUS83307.1 - 0.098 12.4 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide TMEM154 PF15102.6 RUS83307.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 RUS83307.1 - 0.15 11.8 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Vpu protein Macoilin PF09726.9 RUS83308.1 - 0.031 12.9 0.2 0.039 12.5 0.2 1.0 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 RUS83310.1 - 1.3e-57 195.2 0.0 1.7e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83310.1 - 5.1e-29 101.4 0.1 7.1e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS83310.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS83310.1 - 0.0021 16.9 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PRD_Mga PF08270.11 RUS83310.1 - 0.077 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Kdo PF06293.14 RUS83310.1 - 0.099 12.0 0.1 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS83310.1 - 0.13 11.2 1.6 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain SH2_2 PF14633.6 RUS83311.1 - 1.7e-84 282.5 0.5 4.9e-84 281.1 0.5 1.8 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 RUS83311.1 - 7.2e-43 145.9 0.0 7.2e-43 145.9 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 RUS83311.1 - 2.5e-39 133.8 0.0 5.2e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 RUS83311.1 - 8.1e-23 81.0 1.8 4.3e-22 78.7 1.8 2.3 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 RUS83311.1 - 1.3e-10 41.7 37.2 1.3e-10 41.7 37.2 6.5 2 1 3 5 5 3 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 RUS83311.1 - 1.1e-08 35.2 0.0 6.7e-08 32.7 0.0 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif S1 PF00575.23 RUS83311.1 - 5.5e-07 29.8 0.1 1.6e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 RUS83311.1 - 6.3e-07 29.4 0.0 9.4e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 RUS83311.1 - 6.4e-06 27.0 0.3 4.8e-05 24.2 0.3 2.7 1 0 0 1 1 1 1 HHH domain Tex_N PF09371.10 RUS83311.1 - 7.3e-06 25.8 7.3 0.038 13.7 0.0 4.3 5 1 1 6 6 6 2 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 RUS83311.1 - 9e-05 22.9 0.1 0.00039 20.9 0.0 2.1 2 0 0 2 2 2 1 Tex protein YqgF-like domain Ras PF00071.22 RUS83312.1 - 6.2e-50 169.0 0.0 7.5e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS83312.1 - 2.4e-30 105.2 0.0 4.2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS83312.1 - 2e-10 40.4 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 RUS83312.1 - 5.8e-05 23.4 0.1 0.0003 21.2 0.1 1.9 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 RUS83312.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS83312.1 - 0.0045 16.9 0.1 0.71 9.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 RUS83312.1 - 0.0086 15.5 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS83312.1 - 0.023 14.2 0.3 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RUS83312.1 - 0.029 14.1 0.0 0.036 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain ArgoMid PF16487.5 RUS83312.1 - 0.032 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute Pox_A32 PF04665.12 RUS83312.1 - 0.044 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 RUS83312.1 - 0.054 12.7 1.1 1.9 7.6 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 RUS83312.1 - 0.089 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 RUS83312.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 RUS83312.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 RUS83312.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RUS83312.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 RUS83312.1 - 0.2 10.8 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 XRCC1_N PF01834.16 RUS83313.1 - 1.3e-37 129.1 0.0 3.1e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 XRCC1 N terminal domain zf-C2HC_2 PF13913.6 RUS83313.1 - 0.00099 18.9 0.9 0.0046 16.8 0.2 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type PrmA PF06325.13 RUS83314.1 - 9.1e-11 41.7 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 RUS83314.1 - 9.1e-10 38.5 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 RUS83314.1 - 7.9e-06 26.5 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS83314.1 - 5.3e-05 22.9 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 RUS83314.1 - 0.00062 19.6 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS83314.1 - 0.0017 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 RUS83314.1 - 0.0029 17.4 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RUS83314.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 RUS83314.1 - 0.068 13.8 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RUS83314.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NPH-II PF12011.8 RUS83314.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NPH-II DOT1 PF08123.13 RUS83314.1 - 0.22 11.0 0.0 0.66 9.5 0.0 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 Ras PF00071.22 RUS83315.1 - 1.1e-58 197.4 0.2 1.5e-58 197.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS83315.1 - 7.8e-34 116.5 0.5 1.5e-33 115.5 0.1 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS83315.1 - 3.1e-15 56.1 0.2 3.9e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS83315.1 - 7.1e-07 29.0 0.4 3.9e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS83315.1 - 1.2e-05 25.3 0.1 2e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS83315.1 - 4.7e-05 22.8 0.4 0.00014 21.4 0.4 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS83315.1 - 0.00029 20.8 1.1 0.029 14.3 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 RUS83315.1 - 0.00046 19.9 0.1 0.028 14.2 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 RUS83315.1 - 0.00068 20.1 0.0 0.0014 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS83315.1 - 0.0044 17.3 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RUS83315.1 - 0.0063 16.2 1.3 0.086 12.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 RUS83315.1 - 0.013 15.1 0.2 0.1 12.1 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 RUS83315.1 - 0.02 14.6 1.3 0.042 13.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 RUS83315.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 RUS83315.1 - 0.033 13.7 0.1 0.53 9.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RUS83315.1 - 0.045 13.8 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RUS83315.1 - 0.056 13.4 0.1 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 NACHT domain CLN5 PF15014.6 RUS83315.1 - 0.074 12.7 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 AAA_7 PF12775.7 RUS83315.1 - 0.08 12.5 0.0 0.68 9.4 0.0 2.0 1 1 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 RUS83315.1 - 0.084 13.4 1.0 0.2 12.2 1.0 1.9 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 RUS83315.1 - 0.087 12.2 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 RUS83315.1 - 0.17 12.4 1.3 1.5 9.4 1.3 2.1 1 1 0 1 1 1 0 AAA domain Beta-lactamase PF00144.24 RUS83316.1 - 8.9e-56 189.5 0.0 4.3e-55 187.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 RUS83316.1 - 0.0061 16.0 0.1 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 RUS83316.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family Tantalus PF15386.6 RUS83318.1 - 0.00026 21.0 0.1 0.00066 19.7 0.1 1.7 1 0 0 1 1 1 1 Drosophila Tantalus-like Mito_carr PF00153.27 RUS83319.1 - 2e-64 213.6 3.0 4.6e-22 77.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cu-oxidase PF00394.22 RUS83319.1 - 0.0068 16.5 0.1 0.065 13.4 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase DUF2615 PF11027.8 RUS83320.1 - 2e-29 101.8 0.1 2.3e-29 101.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) FixQ PF05545.11 RUS83320.1 - 0.045 13.7 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PSP PF04046.16 RUS83321.1 - 1.6e-15 56.7 0.1 3.1e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 RUS83321.1 - 0.25 11.5 0.5 0.45 10.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle HscB_4_cys PF18256.1 RUS83321.1 - 0.32 10.9 1.4 0.63 9.9 1.4 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Thioredoxin_6 PF13848.6 RUS83322.1 - 0.0008 19.4 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS83323.1 - 4.7e-23 81.3 0.0 4.2e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS83323.1 - 7.4e-08 32.8 0.0 0.00072 20.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 RUS83323.1 - 3.1e-07 30.3 0.0 0.00041 20.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 RUS83323.1 - 0.0071 16.3 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 RUS83323.1 - 0.026 14.2 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Redoxin UPF0203 PF05254.12 RUS83324.1 - 2.8e-23 82.0 3.6 3.3e-23 81.7 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 RUS83324.1 - 0.00035 20.6 1.8 0.016 15.4 0.1 2.2 2 0 0 2 2 2 1 CHCH domain DUF5339 PF17274.2 RUS83324.1 - 0.0026 18.6 4.7 0.11 13.3 0.7 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5339) UCR_hinge PF02320.16 RUS83324.1 - 0.0055 16.9 5.2 0.59 10.4 0.4 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 RUS83324.1 - 0.0066 16.8 1.4 0.022 15.1 1.5 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 RUS83324.1 - 0.0074 16.3 3.9 1 9.4 0.2 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Elongin_A PF06881.11 RUS83324.1 - 0.014 15.9 0.1 0.018 15.6 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Jag_N PF14804.6 RUS83324.1 - 0.016 15.5 0.4 0.023 15.0 0.4 1.3 1 0 0 1 1 1 0 Jag N-terminus RBD PF02196.15 RUS83324.1 - 0.031 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Raf-like Ras-binding domain Pet191_N PF10203.9 RUS83324.1 - 0.05 13.9 3.5 1.2 9.5 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Prolamin_like PF05617.11 RUS83324.1 - 0.057 13.6 0.9 7.7 6.8 0.1 2.0 1 1 1 2 2 2 0 Prolamin-like DUF1910 PF08928.10 RUS83324.1 - 0.06 13.3 0.0 0.09 12.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Acyl-CoA_dh_M PF02770.19 RUS83325.1 - 1.1e-20 73.6 0.0 2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS83325.1 - 1.2e-16 61.4 0.0 1.8e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 RUS83325.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Tma16 PF11176.8 RUS83325.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 MBF1 PF08523.10 RUS83326.1 - 2.3e-23 82.4 3.1 2.3e-23 82.4 3.1 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 RUS83326.1 - 2.5e-13 49.8 0.5 4.3e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 RUS83326.1 - 0.00018 21.8 0.1 0.00048 20.4 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 RUS83326.1 - 0.067 13.2 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 RUS83326.1 - 0.08 13.0 0.2 0.14 12.3 0.2 1.4 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF1690 PF07956.11 RUS83326.1 - 0.25 11.8 5.1 0.31 11.4 5.1 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Patched PF02460.18 RUS83328.1 - 4.7e-74 249.9 6.3 5.6e-74 249.7 6.3 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 RUS83328.1 - 1.1e-23 83.7 0.3 1.1e-23 83.7 0.3 2.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation PDEase_I PF00233.19 RUS83329.1 - 2e-92 309.3 2.3 3e-92 308.7 2.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 RUS83330.1 - 2.1e-09 38.1 0.5 4.1e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) HATPase_c_5 PF14501.6 RUS83331.1 - 0.99 9.3 5.9 0.33 10.9 0.4 2.7 3 0 0 3 3 3 0 GHKL domain Sulfotransfer_1 PF00685.27 RUS83332.1 - 1.5e-22 80.4 0.2 1.9e-22 80.0 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS83332.1 - 2.1e-10 41.4 0.0 9.4e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS83332.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family CBM77 PF18283.1 RUS83333.1 - 0.073 13.4 0.1 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding module 77 PAX PF00292.18 RUS83334.1 - 4.9e-58 194.5 0.3 8.1e-58 193.8 0.3 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 RUS83334.1 - 9.8e-07 28.4 0.3 2.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 RUS83334.1 - 0.0001 22.9 0.0 0.01 16.4 0.0 2.7 1 1 1 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 RUS83334.1 - 0.00022 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 RUS83334.1 - 0.00074 19.5 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 RUS83334.1 - 0.023 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pex24p PF06398.11 RUS83334.1 - 0.2 10.6 3.4 0.28 10.1 3.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2207 PF09972.9 RUS83334.1 - 0.84 8.3 3.3 1.2 7.8 3.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TFIIA PF03153.13 RUS83334.1 - 5.7 6.8 14.5 3.2 7.6 12.7 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 RUS83335.1 - 3.2e-56 191.0 0.3 4.1e-56 190.7 0.3 1.1 1 0 0 1 1 1 1 DDHD domain PSD4 PF07631.11 RUS83335.1 - 0.076 13.6 0.5 0.12 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Pkinase PF00069.25 RUS83336.1 - 4.8e-27 95.0 0.0 6e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83336.1 - 1e-14 54.4 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS83336.1 - 1.6e-10 40.4 0.1 1.6e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS83336.1 - 0.0078 16.2 0.1 0.1 12.5 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RUS83336.1 - 0.008 15.2 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 RUS83336.1 - 0.057 13.0 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.16 RUS83336.1 - 0.11 12.6 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 RUS83336.1 - 0.15 11.4 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 RUS83337.1 - 0.021 13.1 34.2 0.029 12.6 34.2 1.1 1 0 0 1 1 1 0 Nop14-like family E2_bind PF08825.10 RUS83337.1 - 0.071 13.3 0.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 E2 binding domain Peptidase_U4 PF03419.13 RUS83337.1 - 0.22 10.8 2.8 0.35 10.1 2.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SDA1 PF05285.12 RUS83337.1 - 0.23 10.8 36.7 0.35 10.3 36.7 1.2 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 RUS83337.1 - 1.4 7.6 5.6 2.3 6.9 5.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 RUS83337.1 - 1.9 8.3 10.9 3.2 7.5 10.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein LRR_6 PF13516.6 RUS83338.1 - 8.8e-12 44.1 5.4 3.9e-05 23.4 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat EF-hand_1 PF00036.32 RUS83338.1 - 7.7e-11 40.8 3.1 0.00016 20.9 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS83338.1 - 1.6e-08 33.8 1.2 0.00096 18.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS83338.1 - 5.1e-07 30.0 1.0 1.9e-06 28.2 0.5 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS83338.1 - 5.7e-06 26.1 2.4 3.3e-05 23.7 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS83338.1 - 7.8e-06 25.2 2.8 0.0085 15.5 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 RUS83338.1 - 0.041 14.8 0.0 0.078 13.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain LRR_1 PF00560.33 RUS83338.1 - 0.087 13.4 8.7 0.39 11.4 0.0 4.5 4 2 0 4 4 4 0 Leucine Rich Repeat EF-hand_4 PF12763.7 RUS83338.1 - 0.16 11.9 0.2 0.66 10.0 0.1 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand LRR_4 PF12799.7 RUS83338.1 - 0.23 11.9 6.3 3.1 8.4 0.1 3.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) TFIIS_M PF07500.14 RUS83339.1 - 2.7e-36 124.5 2.6 2.7e-36 124.5 2.6 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 RUS83339.1 - 2.8e-17 62.3 8.9 5.5e-17 61.3 8.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 RUS83339.1 - 6.3e-12 45.3 1.9 6.3e-12 45.3 1.9 2.5 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 RUS83339.1 - 0.094 12.4 2.1 0.21 11.3 2.1 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Vps39_1 PF10366.9 RUS83339.1 - 0.45 10.8 2.2 0.31 11.4 0.2 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 SoDot-IcmSS PF16848.5 RUS83340.1 - 0.016 15.2 0.2 0.031 14.3 0.2 1.5 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative DUF1514 PF07438.11 RUS83340.1 - 0.18 11.7 0.3 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) RRM_1 PF00076.22 RUS83341.1 - 4.8e-26 90.4 0.0 1.8e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 RUS83341.1 - 1e-17 64.8 0.6 1e-17 64.8 0.6 1.6 2 0 0 2 2 2 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 RUS83342.1 - 1.9e-15 56.4 0.0 0.00014 21.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX5B PF01215.19 RUS83343.1 - 1.1e-16 60.7 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PAP2 PF01569.21 RUS83344.1 - 6.4e-26 90.7 4.3 6.4e-26 90.7 4.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 RUS83344.1 - 0.00034 20.4 4.6 0.0014 18.4 3.4 2.5 1 1 0 1 1 1 1 PAP2 superfamily Phage_holin_3_1 PF05106.12 RUS83344.1 - 0.013 16.0 0.2 0.034 14.6 0.2 1.7 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) PAP2_C PF14360.6 RUS83344.1 - 0.69 10.5 10.8 0.049 14.2 3.0 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Ldl_recept_b PF00058.17 RUS83345.1 - 1.6e-16 60.5 5.4 1.2e-08 35.3 0.4 3.7 4 0 0 4 4 4 2 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 RUS83346.1 - 0.00013 22.3 2.9 0.4 11.2 0.1 4.1 5 0 0 5 5 5 2 Low-density lipoprotein receptor repeat class B Sushi PF00084.20 RUS83346.1 - 0.0021 18.6 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Gal-3-0_sulfotr PF06990.11 RUS83347.1 - 2.1e-19 69.7 0.3 2.4e-19 69.5 0.3 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS83347.1 - 0.028 14.3 0.0 0.079 12.8 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family Galactosyl_T PF01762.21 RUS83348.1 - 2.1e-21 76.7 0.0 3.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Vps8 PF12816.7 RUS83349.1 - 1.2e-64 217.5 0.9 3.3e-59 199.7 0.0 4.1 4 0 0 4 4 4 3 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 RUS83349.1 - 8.8e-13 48.3 7.7 3.6e-08 33.4 0.1 4.7 5 0 0 5 5 5 2 Region in Clathrin and VPS zf-RING_2 PF13639.6 RUS83349.1 - 0.00069 19.9 2.7 0.0026 18.1 2.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS83349.1 - 0.00099 18.8 1.2 0.0033 17.1 1.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 RUS83349.1 - 0.0017 18.3 2.3 0.0017 18.3 2.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS83349.1 - 0.0021 18.1 2.0 0.0076 16.3 2.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 RUS83349.1 - 0.0033 17.3 2.2 0.0085 16.0 2.2 1.8 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 RUS83349.1 - 0.0067 16.3 2.1 0.024 14.5 2.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 RUS83349.1 - 0.012 15.9 0.1 0.16 12.3 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_1 PF14446.6 RUS83349.1 - 0.012 15.5 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 RUS83349.1 - 0.017 14.9 1.2 0.061 13.2 1.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS83349.1 - 0.032 14.5 0.6 0.1 12.9 0.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 RUS83349.1 - 0.093 12.9 1.5 0.16 12.2 0.5 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain CABIT PF12736.7 RUS83350.1 - 4.1e-09 36.1 1.6 6.6e-08 32.2 1.4 2.6 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, CABIT PF12736.7 RUS83351.1 - 1.6e-21 76.9 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, PBP1_TM PF14812.6 RUS83352.1 - 0.0053 17.1 2.5 0.014 15.8 2.5 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 RUS83352.1 - 0.12 12.7 3.9 0.28 11.6 3.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SAPS PF04499.15 RUS83353.1 - 0.04 12.7 1.8 0.057 12.2 1.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein M60-like_N PF17291.2 RUS83353.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases SDA1 PF05285.12 RUS83353.1 - 2 7.7 40.5 4.4 6.6 40.5 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS83353.1 - 9.4 4.3 39.3 18 3.3 39.3 1.4 1 0 0 1 1 1 0 Nop14-like family PDEase_I PF00233.19 RUS83356.1 - 5.8e-63 212.8 7.2 5.8e-63 212.8 7.2 2.5 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RUS83356.1 - 3e-20 73.2 0.0 4.4e-13 50.0 0.0 3.6 3 1 0 3 3 3 2 GAF domain GAF_2 PF13185.6 RUS83356.1 - 5.4e-10 39.7 0.0 1.4e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RUS83356.1 - 2.8e-09 37.4 0.0 0.023 15.1 0.0 3.4 3 0 0 3 3 3 3 GAF domain AAA_7 PF12775.7 RUS83356.1 - 0.0035 16.9 0.8 0.0068 15.9 0.8 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region SpoVT_C PF15714.5 RUS83356.1 - 0.0076 16.3 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor G0-G1_switch_2 PF15103.6 RUS83356.1 - 5.8 7.4 7.7 1.2 9.6 1.3 2.9 3 0 0 3 3 3 0 G0/G1 switch protein 2 Glyco_transf_10 PF00852.19 RUS83357.1 - 3.6e-46 157.1 0.0 5.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS83357.1 - 0.00019 21.8 0.1 0.00055 20.4 0.1 1.8 1 1 0 1 1 1 1 Fucosyltransferase, N-terminal Tnp_zf-ribbon_2 PF13842.6 RUS83357.1 - 0.08 13.8 1.0 0.23 12.3 1.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2207 PF09972.9 RUS83358.1 - 0.31 9.8 8.1 0.36 9.5 8.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4220 PF13968.6 RUS83358.1 - 2.8 7.3 5.0 3.9 6.8 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) Baculo_11_kDa PF06143.11 RUS83358.1 - 3.3 7.4 13.9 6.3 6.4 13.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family CH PF00307.31 RUS83359.1 - 6.3e-16 58.5 4.7 1.2e-15 57.6 0.0 3.7 4 1 0 4 4 4 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS83359.1 - 2e-05 24.3 0.0 9.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain Phage_Mu_Gp45 PF06890.12 RUS83359.1 - 0.0083 15.9 0.0 0.039 13.7 0.0 2.2 1 0 0 1 1 1 1 Bacteriophage Mu Gp45 protein YabA PF06156.13 RUS83359.1 - 9.2 7.0 71.6 0.19 12.4 4.4 6.9 6 1 1 7 7 7 0 Initiation control protein YabA CN_hydrolase PF00795.22 RUS83360.1 - 5.9e-59 199.5 0.0 7.1e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Metallopep PF12044.8 RUS83361.1 - 3e-78 263.3 0.0 3.4e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 RUS83361.1 - 0.0022 18.2 0.4 0.0037 17.5 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS83361.1 - 0.0085 16.6 0.9 0.043 14.3 0.6 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Copine PF07002.16 RUS83363.1 - 8.7e-62 208.4 0.3 1.1e-61 208.0 0.3 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RUS83363.1 - 2.4e-11 44.1 0.1 4.5e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus YcbB PF08664.10 RUS83363.1 - 0.038 14.0 0.6 0.073 13.1 0.2 1.6 2 0 0 2 2 2 0 YcbB domain Sugar_tr PF00083.24 RUS83365.1 - 1.6e-13 50.3 0.7 2e-13 50.0 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS83365.1 - 2.9e-11 42.9 12.4 8.1e-11 41.4 12.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1478 PF07349.11 RUS83365.1 - 0.0018 18.2 0.5 0.0029 17.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1478) MFS_1_like PF12832.7 RUS83365.1 - 0.002 17.1 0.7 0.0026 16.7 0.7 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RUS83366.1 - 2.1e-15 56.5 15.3 3.3e-15 55.9 15.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS83366.1 - 2.9e-12 46.2 9.2 3.6e-12 45.9 9.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter BclA_C PF18573.1 RUS83366.1 - 0.034 14.0 0.2 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 BclA C-terminal domain MFS_Mycoplasma PF07672.13 RUS83366.1 - 0.038 13.3 3.0 0.063 12.5 3.0 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter Neuroparsin PF07327.11 RUS83366.1 - 0.078 13.4 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Neuroparsin RNase_H PF00075.24 RUS83367.1 - 8.1e-10 39.0 0.0 1.8e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS83367.1 - 5.1e-06 26.3 0.0 7.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Phospholip_A2_2 PF05826.12 RUS83368.1 - 4.7e-36 122.9 0.6 1e-35 121.8 0.6 1.6 1 0 0 1 1 1 1 Phospholipase A2 PPR_2 PF13041.6 RUS83368.1 - 0.22 11.7 1.2 0.54 10.5 1.2 1.6 1 0 0 1 1 1 0 PPR repeat family Phospholip_A2_1 PF00068.19 RUS83368.1 - 0.41 11.1 15.0 1.5 9.3 8.8 3.2 2 1 0 2 2 2 0 Phospholipase A2 CH PF00307.31 RUS83369.1 - 1.5e-12 47.7 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Filamin PF00630.19 RUS83369.1 - 4.2e-09 37.2 0.0 1.5e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Filamin/ABP280 repeat CAMSAP_CH PF11971.8 RUS83369.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Exo5 PF09810.9 RUS83370.1 - 2.4e-47 162.2 3.6 5.4e-19 68.9 0.0 3.3 2 1 1 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 RUS83370.1 - 4e-05 23.7 0.7 9.1e-05 22.5 0.7 1.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Rep_fac_C PF08542.11 RUS83372.1 - 1.4e-22 79.9 0.1 1.5e-21 76.6 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 RUS83372.1 - 3.7e-18 66.2 0.0 7.1e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RUS83372.1 - 3.2e-15 56.3 0.0 3.5e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 RUS83372.1 - 5.2e-09 36.3 0.0 1.5e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 RUS83372.1 - 6.2e-06 26.2 0.1 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RUS83372.1 - 2.5e-05 24.1 0.0 6.2e-05 22.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RUS83372.1 - 7e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS83372.1 - 0.00012 22.5 0.0 0.00035 21.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS83372.1 - 0.00016 21.9 0.2 0.16 12.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 RUS83372.1 - 0.00021 21.1 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 RUS83372.1 - 0.00077 18.7 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 RUS83372.1 - 0.0008 19.4 0.0 0.16 12.0 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RUS83372.1 - 0.00084 19.7 0.5 0.2 12.0 0.0 3.0 2 1 0 3 3 3 1 AAA domain AAA_assoc_2 PF16193.5 RUS83372.1 - 0.0016 18.8 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 RUS83372.1 - 0.0017 18.4 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS83372.1 - 0.0028 17.2 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 RUS83372.1 - 0.0031 17.3 0.2 0.078 12.7 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 RUS83372.1 - 0.0034 16.9 0.3 0.19 11.1 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 RUS83372.1 - 0.004 16.9 0.1 0.028 14.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RUS83372.1 - 0.0049 16.3 0.1 0.48 9.8 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RUS83372.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 RUS83372.1 - 0.011 15.2 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 RUS83372.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 RUS83372.1 - 0.062 13.1 0.3 0.11 12.3 0.0 1.5 2 0 0 2 2 1 0 DNA polymerase III, delta subunit SNF2_N PF00176.23 RUS83372.1 - 0.07 11.8 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain IstB_IS21 PF01695.17 RUS83372.1 - 0.084 12.6 0.1 0.47 10.2 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 RUS83372.1 - 0.11 12.2 0.0 9.5 5.9 0.0 2.8 4 0 0 4 4 3 0 Sigma-54 interaction domain RecR PF02132.15 RUS83372.1 - 0.13 11.8 0.2 0.37 10.4 0.2 1.7 1 0 0 1 1 1 0 RecR protein Pkinase_Tyr PF07714.17 RUS83373.1 - 4.9e-51 173.5 0.0 7.8e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS83373.1 - 1.3e-39 136.1 0.0 2.4e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 RUS83373.1 - 2.5e-30 105.3 2.2 4.4e-30 104.5 2.2 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 C1_1 PF00130.22 RUS83373.1 - 4.2e-05 23.3 4.2 9.5e-05 22.2 4.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 RUS83373.1 - 0.0043 17.3 4.1 0.0084 16.4 2.8 2.2 2 0 0 2 2 2 1 RING-like domain RIO1 PF01163.22 RUS83373.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Zf_RING PF16744.5 RUS83373.1 - 0.023 14.8 1.6 0.071 13.2 1.6 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Kdo PF06293.14 RUS83373.1 - 0.077 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 RUS83373.1 - 1.3 9.4 3.9 3 8.2 3.9 1.6 1 0 0 1 1 1 0 Ring finger domain PH PF00169.29 RUS83374.1 - 1.6e-13 51.1 0.5 3.2e-13 50.1 0.5 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 RUS83374.1 - 5.3e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS83374.1 - 0.0004 20.8 0.4 0.0025 18.2 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RUS83374.1 - 0.07 13.4 0.1 0.24 11.7 0.1 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PA26 PF04636.13 RUS83374.1 - 1.2 8.0 5.4 4 6.3 0.4 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SPRR2 PF14820.6 RUS83376.1 - 3.3e-07 30.3 69.1 1.6 8.8 7.7 7.4 1 1 6 7 7 7 7 Small proline-rich 2 NAPRTase PF04095.16 RUS83377.1 - 1.8e-68 230.8 0.0 2.4e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 RUS83377.1 - 1.5e-41 140.8 0.1 3.7e-41 139.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) QH-AmDH_gamma PF08992.11 RUS83377.1 - 0.095 12.7 0.0 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, gamma subunit Carb_anhydrase PF00194.21 RUS83378.1 - 2.5e-54 184.5 0.0 3e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase FAM176 PF14851.6 RUS83380.1 - 0.0069 16.1 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 FAM176 family BUD22 PF09073.10 RUS83380.1 - 0.028 13.8 4.5 0.032 13.6 4.5 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RUS83380.1 - 0.12 10.7 11.0 0.15 10.3 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 RUS83380.1 - 0.18 9.8 2.4 0.24 9.5 2.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.16 RUS83380.1 - 0.19 10.9 4.9 0.26 10.4 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit eIF-3c_N PF05470.12 RUS83380.1 - 0.59 8.4 1.7 0.67 8.2 1.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RXT2_N PF08595.11 RUS83380.1 - 0.86 9.6 9.1 1.3 9.0 9.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Pkinase PF00069.25 RUS83383.1 - 1.1e-36 126.6 0.0 1.3e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83383.1 - 1.4e-12 47.5 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS83383.1 - 0.0015 17.4 0.0 0.059 12.1 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase DUF4995 PF16386.5 RUS83383.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function CPSase_L_D2 PF02786.17 RUS83384.1 - 1.5e-81 272.9 0.1 2.4e-81 272.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RUS83384.1 - 1e-44 151.6 0.3 3.2e-44 150.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RUS83384.1 - 2.1e-31 108.2 0.0 6.2e-31 106.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 RUS83384.1 - 1.6e-24 86.6 0.0 5.8e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 RUS83384.1 - 2.5e-13 49.6 2.2 2.5e-13 49.6 2.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 RUS83384.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RUS83384.1 - 2.7e-09 36.9 0.0 6.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 RUS83384.1 - 1.5e-08 34.4 0.2 9.4e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RUS83384.1 - 5.1e-06 26.6 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 RUS83384.1 - 9.5e-06 25.3 0.6 0.0014 18.4 0.5 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.19 RUS83384.1 - 0.0078 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 RUS83384.1 - 0.023 14.3 0.0 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Oxidored_nitro PF00148.19 RUS83384.1 - 0.027 13.2 0.0 3.7 6.2 0.0 2.2 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DEAD PF00270.29 RUS83385.1 - 6.7e-51 172.5 0.0 9.7e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS83385.1 - 8.1e-30 103.4 0.0 1.4e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS83385.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit XFP PF03894.15 RUS83386.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TFIIA PF03153.13 RUS83386.1 - 0.49 10.3 7.2 0.59 10.1 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.24 RUS83387.1 - 7.3e-05 22.6 1.5 7.3e-05 22.6 1.5 2.3 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 RUS83387.1 - 0.0045 17.2 0.6 0.16 12.2 0.2 2.0 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 RUS83387.1 - 0.016 15.7 3.5 0.016 15.7 3.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Myticin-prepro PF10690.9 RUS83387.1 - 0.56 10.5 5.1 1.3 9.3 5.1 1.5 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel NPR3 PF03666.13 RUS83388.1 - 0.0047 15.8 14.3 0.0066 15.3 14.3 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 RUS83388.1 - 0.081 13.1 1.9 0.09 12.9 1.9 1.2 1 0 0 1 1 1 0 DDHD domain PIEZO PF15917.5 RUS83388.1 - 0.37 10.2 13.5 0.43 10.0 13.5 1.1 1 0 0 1 1 1 0 Piezo YL1 PF05764.13 RUS83388.1 - 0.37 10.9 31.4 0.46 10.6 31.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein OATP PF03137.20 RUS83388.1 - 0.37 9.0 4.5 0.43 8.8 4.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SRP-alpha_N PF04086.13 RUS83388.1 - 0.37 10.7 25.0 0.47 10.3 25.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal EMC3_TMCO1 PF01956.16 RUS83388.1 - 1 9.1 6.4 1.2 8.8 6.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 RUS83388.1 - 2.2 6.9 11.6 2.5 6.8 11.6 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 RUS83388.1 - 2.7 7.1 7.4 3.3 6.8 7.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Miga PF10265.9 RUS83388.1 - 3 6.7 9.3 3.6 6.5 9.3 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4569 PF15133.6 RUS83388.1 - 6.2 6.5 7.7 7.1 6.3 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Sec62 PF03839.16 RUS83388.1 - 9.7 5.6 21.8 13 5.2 21.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 zf-CCCH PF00642.24 RUS83389.1 - 6.8e-07 29.0 15.1 0.0091 15.9 1.1 4.6 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Antifungal_prot PF11402.8 RUS83389.1 - 0.0031 17.7 7.9 2.6 8.3 0.3 3.7 3 1 0 3 3 3 3 Antifungal protein zf-CCCH_4 PF18044.1 RUS83389.1 - 0.41 10.5 16.8 1.5 8.7 2.3 4.9 4 1 0 4 4 4 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RUS83389.1 - 0.62 10.6 22.8 0.66 10.5 0.6 4.5 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RUS83389.1 - 3.2 8.0 19.7 1.2 9.3 1.0 4.1 3 1 0 3 3 3 0 Zinc-finger containing family Apt1 PF10351.9 RUS83391.1 - 0.0043 16.0 24.1 0.0043 16.0 24.1 1.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF2213 PF09979.9 RUS83391.1 - 0.044 13.8 1.6 15 5.5 1.6 3.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Presenilin PF01080.17 RUS83391.1 - 0.19 10.5 9.0 0.19 10.5 9.0 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RUS83391.1 - 0.43 9.1 28.5 0.48 8.9 28.5 1.2 1 0 0 1 1 1 0 Macoilin family Velvet PF11754.8 RUS83391.1 - 1.2 9.0 14.4 1.3 8.9 14.4 1.2 1 0 0 1 1 1 0 Velvet factor Pkinase_fungal PF17667.1 RUS83391.1 - 2 7.1 6.4 2.1 7.0 6.4 1.1 1 0 0 1 1 1 0 Fungal protein kinase TamB PF04357.13 RUS83391.1 - 2.1 7.5 14.4 2.8 7.1 14.4 1.2 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex NPR3 PF03666.13 RUS83391.1 - 3.3 6.4 14.4 3.5 6.3 14.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 RUS83391.1 - 5.7 7.6 12.1 8.6 7.0 12.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOBP PF15279.6 RUS83391.1 - 6.8 7.2 16.4 6.9 7.2 16.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein YAF2_RYBP PF17219.3 RUS83392.1 - 7.6 6.2 5.1 28 4.4 0.1 4.4 5 1 0 5 5 5 0 Yaf2/RYBP C-terminal binding motif Mur_ligase_M PF08245.12 RUS83394.1 - 6.2e-06 26.3 0.0 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 RUS83394.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain SCAI PF12070.8 RUS83395.1 - 4.5e-207 689.2 0.0 6.3e-207 688.7 0.0 1.2 1 0 0 1 1 1 1 Protein SCAI Peptidase_M90 PF06167.12 RUS83395.1 - 0.034 13.8 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 2OG-FeII_Oxy_5 PF13759.6 RUS83396.1 - 0.014 15.8 0.4 3.2 8.2 0.1 2.6 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase Choline_transpo PF04515.12 RUS83397.1 - 1.6e-106 356.2 27.0 1.6e-106 356.2 27.0 3.2 3 1 0 3 3 3 1 Plasma-membrane choline transporter DUF440 PF04269.12 RUS83398.1 - 0.78 10.1 11.4 3.5e+03 -1.6 11.4 3.6 1 1 0 1 1 1 0 Protein of unknown function, DUF440 SSF PF00474.17 RUS83399.1 - 4.2e-19 68.7 7.1 4.2e-19 68.7 7.1 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 RUS83400.1 - 6.3e-92 308.5 12.0 8.7e-92 308.1 12.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family PIRT PF15099.6 RUS83400.1 - 0.024 14.2 0.9 0.024 14.2 0.9 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF4231 PF14015.6 RUS83400.1 - 4 8.0 9.4 0.91 10.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Sigma_reg_N PF13800.6 RUS83400.1 - 5 7.5 9.3 9.2 6.6 0.4 3.6 3 1 0 3 3 3 0 Sigma factor regulator N-terminal APC_N_CC PF16689.5 RUS83402.1 - 0.09 12.9 0.5 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain LicD PF04991.13 RUS83403.1 - 5.1e-13 49.7 0.2 5.6e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 LicD family DUF2985 PF11204.8 RUS83403.1 - 0.049 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) 7tm_1 PF00001.21 RUS83404.1 - 2e-49 168.3 23.4 2.8e-49 167.8 23.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS83404.1 - 1.5e-09 37.9 18.8 2.6e-09 37.1 18.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pox_EPC_I2-L1 PF12575.8 RUS83404.1 - 0.14 12.4 0.3 0.14 12.4 0.3 3.5 3 2 2 5 5 5 0 Poxvirus entry protein complex L1 and I2 Phage_terminase PF10668.9 RUS83405.1 - 0.019 15.0 0.0 0.2 11.7 0.0 2.9 2 0 0 2 2 2 0 Phage terminase small subunit Acyltransferase PF01553.21 RUS83406.1 - 1.4e-20 73.3 0.1 4.9e-20 71.5 0.0 1.9 1 1 1 2 2 2 1 Acyltransferase adh_short PF00106.25 RUS83407.1 - 1.2e-27 96.6 0.0 4e-27 95.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS83407.1 - 5.5e-27 94.8 0.0 1.1e-25 90.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS83407.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RUS83407.1 - 0.0088 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding COPIIcoated_ERV PF07970.12 RUS83408.1 - 1.5e-34 119.8 0.0 2.4e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RUS83408.1 - 1e-31 109.1 0.1 1e-31 109.1 0.1 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-H2C2_2 PF13465.6 RUS83409.1 - 4e-27 93.4 139.9 0.00022 21.5 5.2 15.7 15 1 1 16 16 16 11 Zinc-finger double domain zf-C2H2 PF00096.26 RUS83409.1 - 4.2e-26 89.9 136.2 0.0086 16.5 0.7 15.4 15 0 0 15 15 15 13 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS83409.1 - 4.7e-24 83.8 114.4 0.00022 20.9 0.2 14.2 14 0 0 14 14 14 12 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS83409.1 - 5.3e-24 82.8 126.3 0.017 15.9 1.3 15.6 15 0 0 15 15 15 14 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 RUS83409.1 - 0.014 15.0 0.1 0.014 15.0 0.1 12.6 6 3 7 13 13 13 0 Zinc-fingers and homeoboxes C2H2 finger domain RHH_3 PF12651.7 RUS83409.1 - 0.092 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain AAA_19 PF13245.6 RUS83409.1 - 0.21 11.9 0.7 6.6 7.0 0.2 3.1 2 1 1 3 3 3 0 AAA domain DUF2784 PF10861.8 RUS83409.1 - 0.24 11.5 0.3 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) zf-met PF12874.7 RUS83409.1 - 0.34 11.4 0.1 0.34 11.4 0.1 12.8 14 0 0 14 14 14 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS83409.1 - 0.44 10.9 0.0 0.11 12.8 3.4 14.0 14 0 0 14 14 14 0 Zinc-finger double-stranded RNA-binding UPF0047 PF01894.17 RUS83410.1 - 1.1e-25 90.0 0.0 7.4e-25 87.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 YjeF_N PF03853.15 RUS83411.1 - 1.4e-13 51.1 0.0 2.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus LSM14 PF12701.7 RUS83411.1 - 2.9e-06 27.3 0.0 5.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 RUS83411.1 - 6e-06 27.1 0.2 1.5e-05 25.8 0.2 1.6 1 0 0 1 1 1 1 FDF domain VirE2 PF07229.12 RUS83411.1 - 0.091 11.4 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 VirE2 UPF0193 PF05250.11 RUS83411.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Glyco_hydro_59 PF02057.15 RUS83412.1 - 0.00026 20.3 12.0 5.4 6.1 0.0 7.0 1 1 8 9 9 9 1 Glycosyl hydrolase family 59 Propep_M14 PF02244.16 RUS83412.1 - 0.0022 18.3 10.7 46 4.5 0.2 6.9 1 1 5 6 6 6 0 Carboxypeptidase activation peptide Lyase_8_C PF02884.17 RUS83412.1 - 0.015 15.7 8.4 1.2e+02 3.3 0.6 7.4 1 1 2 3 3 3 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain FlaF PF07309.11 RUS83412.1 - 0.072 13.1 1.0 49 4.0 0.0 4.1 1 1 5 7 7 7 0 Flagellar protein FlaF V-set_2 PF15910.5 RUS83412.1 - 0.078 13.1 0.2 0.67 10.1 0.0 2.4 3 0 0 3 3 3 0 ICOS V-set domain DXP_redisom_C PF08436.12 RUS83412.1 - 2.8 8.2 8.5 39 4.5 0.1 4.8 2 2 2 5 5 5 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DMT_YdcZ PF04657.13 RUS83413.1 - 0.044 14.0 0.7 0.083 13.2 0.7 1.4 1 1 0 1 1 1 0 Putative inner membrane exporter, YdcZ Kinesin_assoc PF16183.5 RUS83414.1 - 0.0032 17.7 1.1 0.018 15.2 0.0 2.4 2 1 0 2 2 2 1 Kinesin-associated Nucleo_P87 PF07267.11 RUS83414.1 - 0.92 8.3 4.7 1.3 7.7 4.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 KIF1B PF12423.8 RUS83416.1 - 2.3e-06 27.9 0.3 4.7e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 Kinesin protein 1B DUF4884 PF16225.5 RUS83417.1 - 0.097 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Collagen PF01391.18 RUS83418.1 - 1.7e-05 24.5 27.7 0.11 12.3 9.0 4.2 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) YdjO PF14169.6 RUS83419.1 - 0.00041 20.0 39.0 0.44 10.3 0.4 7.4 2 2 6 8 8 8 4 Cold-inducible protein YdjO Chor_lyase PF04345.13 RUS83419.1 - 0.00045 19.9 5.6 2.5 7.7 0.3 4.6 1 1 1 3 3 3 2 Chorismate lyase TAD2 PF18521.1 RUS83419.1 - 0.0044 16.9 10.5 40 4.4 0.1 5.7 2 1 4 6 6 6 0 Transactivation domain 2 FAO_M PF16350.5 RUS83419.1 - 0.045 14.1 13.7 6.3 7.2 0.1 5.0 2 1 4 6 6 6 0 FAD dependent oxidoreductase central domain Mor PF08765.11 RUS83419.1 - 3.9 7.5 7.0 92 3.1 0.5 4.3 2 1 3 5 5 5 0 Mor transcription activator family mRNA_decap_C PF16741.5 RUS83421.1 - 6e-05 22.3 25.6 0.5 9.7 0.8 5.4 5 0 0 5 5 5 5 mRNA-decapping enzyme C-terminus HRM PF02793.22 RUS83421.1 - 0.028 14.7 0.0 15 5.9 0.1 3.8 1 1 1 2 2 2 0 Hormone receptor domain Baculo_Y142 PF04913.12 RUS83421.1 - 0.23 10.1 4.0 2.2 6.8 0.2 2.7 1 1 2 3 3 3 0 Baculovirus Y142 protein Dymeclin PF09742.9 RUS83421.1 - 0.41 9.0 11.8 8.7 4.6 0.5 3.9 1 1 3 4 4 4 0 Dyggve-Melchior-Clausen syndrome protein Rnf-Nqr PF02508.14 RUS83421.1 - 1.2 9.1 6.0 2.6 8.0 1.5 2.1 1 1 1 2 2 2 0 Rnf-Nqr subunit, membrane protein VTC PF09359.10 RUS83421.1 - 8 5.8 7.2 34 3.7 1.0 3.3 1 1 2 3 3 3 0 VTC domain Mss4 PF04421.13 RUS83423.1 - 2.1e-32 111.1 0.0 2.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein LRR_8 PF13855.6 RUS83426.1 - 4.7e-19 67.9 7.8 1.2e-06 28.2 0.5 3.6 2 1 1 3 3 3 3 Leucine rich repeat CH PF00307.31 RUS83426.1 - 7.7e-14 51.8 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_4 PF12799.7 RUS83426.1 - 3.2e-12 46.4 12.4 0.0036 17.7 0.2 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS83426.1 - 0.56 11.0 15.2 9.2 7.3 0.1 6.4 5 2 0 5 5 5 0 Leucine Rich Repeat GDP_Man_Dehyd PF16363.5 RUS83427.1 - 5.1e-54 183.9 0.2 2.2e-53 181.8 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS83427.1 - 2.5e-50 171.2 0.0 3.3e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RUS83427.1 - 4.3e-11 42.5 0.1 1.6e-06 27.5 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 RUS83427.1 - 1.8e-10 40.3 0.0 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RUS83427.1 - 8.7e-10 38.2 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS83427.1 - 7.6e-08 31.8 0.2 0.00058 19.1 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 RUS83427.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Cupin_8 PF13621.6 RUS83427.1 - 0.16 11.7 0.2 0.29 10.8 0.3 1.3 1 1 0 1 1 1 0 Cupin-like domain NAD_binding_10 PF13460.6 RUS83427.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding HTH_38 PF13936.6 RUS83428.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SMC_N PF02463.19 RUS83429.1 - 2.1e-74 249.7 21.3 1.1e-73 247.4 21.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RUS83429.1 - 3.2e-24 85.5 0.0 1.4e-23 83.4 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RUS83429.1 - 1.6e-12 47.9 10.6 2.6e-06 27.5 1.4 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RUS83429.1 - 7.9e-10 39.0 30.2 7.9e-10 39.0 30.2 4.4 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS83429.1 - 2e-05 24.3 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF745 PF05335.13 RUS83429.1 - 4.6e-05 23.2 5.5 4.6e-05 23.2 5.5 5.5 3 1 4 7 7 5 2 Protein of unknown function (DUF745) AAA_13 PF13166.6 RUS83429.1 - 0.00021 20.1 20.3 0.00021 20.1 20.3 6.3 3 2 3 6 6 5 2 AAA domain AAA_23 PF13476.6 RUS83429.1 - 0.00025 21.6 33.1 0.00025 21.6 33.1 7.4 2 2 2 4 4 1 1 AAA domain ATG16 PF08614.11 RUS83429.1 - 0.0015 18.8 28.3 0.0029 17.9 9.6 7.7 2 2 7 9 9 7 3 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 RUS83429.1 - 0.0027 17.5 10.5 0.0027 17.5 10.5 8.4 4 2 4 8 8 6 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 RUS83429.1 - 0.0029 16.6 6.0 0.0029 16.6 6.0 7.6 2 2 5 8 8 8 3 Spc7 kinetochore protein COG2 PF06148.11 RUS83429.1 - 0.0066 16.5 6.0 0.0066 16.5 6.0 8.6 4 3 4 8 8 6 3 COG (conserved oligomeric Golgi) complex component, COG2 AAA_22 PF13401.6 RUS83429.1 - 0.02 15.1 0.0 2.7 8.3 0.0 3.5 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 RUS83429.1 - 0.022 15.3 0.0 0.022 15.3 0.0 6.5 3 2 1 5 5 4 0 ABC transporter DUF1664 PF07889.12 RUS83429.1 - 0.023 14.7 1.0 0.023 14.7 1.0 9.8 4 3 5 11 11 11 0 Protein of unknown function (DUF1664) Img2 PF05046.14 RUS83429.1 - 0.21 11.9 11.1 1.1 9.6 0.2 4.4 3 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) FTO_CTD PF12934.7 RUS83429.1 - 2.9 7.6 22.1 0.037 13.8 1.2 4.3 2 1 0 3 3 3 0 FTO C-terminal domain RabGAP-TBC PF00566.18 RUS83431.1 - 1e-53 182.2 0.0 1.3e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Apo-VLDL-II PF05418.11 RUS83432.1 - 0.0072 16.9 0.0 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 Apovitellenin I (Apo-VLDL-II) NOA36 PF06524.12 RUS83432.1 - 0.043 13.1 0.7 0.071 12.4 0.7 1.3 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_108 PF05838.12 RUS83432.1 - 0.12 12.9 0.1 0.3 11.6 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase 108 zf-RING_10 PF16685.5 RUS83433.1 - 3.8e-24 84.6 9.2 5.3e-24 84.1 9.2 1.2 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 RUS83433.1 - 1.3 9.0 10.9 0.78 9.7 3.8 2.8 3 0 0 3 3 3 0 zinc-RING finger domain Sugar_tr PF00083.24 RUS83434.1 - 4.6e-29 101.6 25.0 6.1e-29 101.2 25.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS83434.1 - 4.1e-20 72.0 46.5 4.2e-17 62.1 28.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily 7tm_1 PF00001.21 RUS83435.1 - 0.0055 16.1 7.6 0.0085 15.5 7.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Solute_trans_a PF03619.16 RUS83435.1 - 0.055 13.0 5.3 0.076 12.5 5.3 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha MCM PF00493.23 RUS83436.1 - 7.4e-101 335.9 0.0 1.1e-100 335.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RUS83436.1 - 1e-35 122.3 0.7 2.3e-35 121.2 0.7 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS83436.1 - 2.4e-22 79.2 1.8 5.5e-22 78.0 1.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RUS83436.1 - 2.5e-21 76.2 2.5 6.9e-21 74.8 1.8 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 RUS83436.1 - 4.9e-07 29.3 0.1 2.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS83436.1 - 1.1e-06 28.6 0.0 4.2e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 RUS83436.1 - 0.0025 18.4 0.8 0.024 15.3 0.4 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal MCM_bind PF09739.9 RUS83436.1 - 0.0026 16.3 0.1 0.0043 15.6 0.1 1.2 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_lid_2 PF17863.1 RUS83436.1 - 0.0045 16.8 2.1 0.011 15.5 0.9 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 RUS83436.1 - 0.0058 16.5 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIG-S PF10510.9 RUS83436.1 - 0.08 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein RlaP PF10127.9 RUS83436.1 - 0.09 12.4 0.1 0.41 10.2 0.0 2.0 1 1 1 2 2 2 0 RNA repair pathway DNA polymerase beta family Sigma54_activat PF00158.26 RUS83436.1 - 0.14 11.9 0.0 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain HLH PF00010.26 RUS83438.1 - 4.8e-14 52.0 2.4 4.8e-14 52.0 2.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS83438.1 - 1.4e-13 50.8 0.1 1.4e-13 50.8 0.1 2.9 3 0 0 3 3 3 1 Hairy Orange LSM PF01423.22 RUS83439.1 - 4.1e-21 74.5 0.0 5e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain VPS13 PF16908.5 RUS83440.1 - 8.5e-22 78.1 3.5 8.5e-22 78.1 3.5 1.7 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 RUS83440.1 - 1.4e-07 31.2 1.8 1.1e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Repeating coiled region of VPS13 DUF2076 PF09849.9 RUS83440.1 - 0.019 15.0 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MNE1 PF13762.6 RUS83441.1 - 0.028 14.4 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component IgGFc_binding PF17517.2 RUS83443.1 - 1.5e-13 50.7 7.2 1.5e-13 50.7 7.2 1.5 1 1 0 1 1 1 1 IgGFc binding protein Cu-binding_MopE PF11617.8 RUS83443.1 - 0.0047 17.1 1.8 0.008 16.3 1.8 1.4 1 0 0 1 1 1 1 Putative metal-binding motif Oxysterol_BP PF01237.18 RUS83446.1 - 3.4e-38 131.5 0.0 4.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Amastin PF07344.11 RUS83448.1 - 0.0008 19.3 3.1 0.0011 18.8 3.1 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Cul7 PF11515.8 RUS83448.1 - 0.016 15.5 0.1 0.12 12.6 0.1 2.2 1 1 1 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 SUR7 PF06687.12 RUS83448.1 - 0.33 10.5 11.4 1.5 8.4 11.3 2.2 1 1 0 1 1 1 0 SUR7/PalI family TFIIA PF03153.13 RUS83449.1 - 0.21 11.5 21.0 0.32 10.9 21.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 RUS83449.1 - 0.25 10.0 13.2 0.37 9.5 13.2 1.1 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.10 RUS83449.1 - 1.1 9.5 11.2 2 8.6 11.2 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.22 RUS83449.1 - 1.5 8.0 17.4 2.2 7.4 17.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 RUS83449.1 - 2.1 6.8 11.8 3 6.3 11.8 1.1 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 RUS83449.1 - 4.7 5.4 22.3 6.3 4.9 22.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 RUS83449.1 - 5.4 6.4 13.9 8.3 5.8 13.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin BORG_CEP PF14957.6 RUS83449.1 - 5.4 8.2 9.7 13 6.9 9.7 1.6 1 0 0 1 1 1 0 Cdc42 effector BPL_N PF09825.9 RUS83449.1 - 6.6 5.7 10.0 3.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal CAF1A PF12253.8 RUS83450.1 - 0.025 14.7 13.2 0.044 14.0 5.7 2.5 2 1 1 3 3 3 0 Chromatin assembly factor 1 subunit A Mlp PF03304.13 RUS83450.1 - 0.069 13.4 2.0 0.12 12.6 2.0 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family TrbE PF11100.8 RUS83452.1 - 7.3e-06 26.1 2.4 1.6 9.0 0.1 3.9 2 2 2 4 4 4 3 Conjugal transfer protein TrbE EGF_alliinase PF04863.13 RUS83452.1 - 4e-05 23.9 4.4 11 6.5 0.0 5.0 5 0 0 5 5 5 3 Alliinase EGF-like domain F-protein PF00469.20 RUS83452.1 - 0.007 16.0 1.3 1.7 8.2 0.0 3.2 2 1 1 3 3 3 1 Negative factor, (F-Protein) or Nef EGF_2 PF07974.13 RUS83452.1 - 0.14 12.6 5.8 85 3.6 0.1 4.9 5 0 0 5 5 5 0 EGF-like domain SKN1 PF03935.15 RUS83452.1 - 2.3 6.5 6.0 7.9 4.8 0.2 2.8 2 1 1 3 3 3 0 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.16 RUS83454.1 - 8.3e-19 67.7 34.6 8.7e-14 51.2 16.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS83454.1 - 1.5e-07 30.7 1.3 2.6e-06 26.6 0.9 2.0 2 0 0 2 2 2 1 MFS_1 like family C9orf72-like PF15019.6 RUS83454.1 - 0.089 12.3 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 C9orf72-like protein family Orthopox_F14 PF06076.12 RUS83454.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus F14 protein HR1 PF02185.16 RUS83455.1 - 0.0032 17.5 0.8 12 6.1 0.1 3.8 1 1 1 2 2 2 2 Hr1 repeat CdiI_3 PF18616.1 RUS83455.1 - 0.0068 16.3 4.8 4.7 7.1 0.1 4.3 1 1 6 7 7 7 1 CDI immunity proteins IncFII_repA PF02387.15 RUS83455.1 - 0.032 13.5 1.0 2.7 7.1 0.2 2.2 1 1 1 2 2 2 0 IncFII RepA protein family Tsi6 PF18660.1 RUS83455.1 - 0.15 12.1 2.2 26 4.9 0.1 3.2 1 1 2 3 3 3 0 Tsi6 Rsd_AlgQ PF04353.13 RUS83455.1 - 0.24 11.4 8.8 2.5 8.0 1.2 3.0 1 1 2 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ COLFI PF01410.18 RUS83455.1 - 0.54 9.5 8.4 5.7 6.2 3.4 2.7 1 1 1 2 2 2 0 Fibrillar collagen C-terminal domain MFS_1 PF07690.16 RUS83456.1 - 0.00044 19.3 31.4 0.0011 18.0 6.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Pet100 PF09803.9 RUS83456.1 - 0.081 13.5 0.4 0.27 11.8 0.4 1.9 1 0 0 1 1 1 0 Pet100 zf-H2C2_2 PF13465.6 RUS83457.1 - 4.5e-14 52.1 21.1 6.2e-06 26.4 0.1 5.9 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 RUS83457.1 - 2.8e-12 46.4 33.9 0.0047 17.3 0.7 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS83457.1 - 2.1e-10 40.2 32.0 4e-05 23.3 0.6 4.9 5 0 0 5 5 4 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS83457.1 - 3e-09 36.9 34.1 0.05 14.5 0.2 6.4 5 1 1 6 6 6 5 C2H2-type zinc finger NinD PF17466.2 RUS83457.1 - 0.0043 17.1 2.7 0.011 15.8 0.5 2.3 2 0 0 2 2 2 1 Family of unknown function HalOD2 PF18547.1 RUS83457.1 - 0.077 12.9 0.1 0.077 12.9 0.1 2.6 4 0 0 4 4 4 0 Halobacterial output domain 2 zf-C2H2_jaz PF12171.8 RUS83457.1 - 0.15 12.4 8.4 1.4 9.3 0.0 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS83457.1 - 1.3 9.1 9.2 20 5.3 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Elf1 PF05129.13 RUS83457.1 - 1.4 9.0 16.9 0.098 12.7 2.0 4.0 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like CpXC PF14353.6 RUS83457.1 - 1.5 8.9 15.8 12 6.0 0.2 4.3 1 1 3 4 4 4 0 CpXC protein zf_UBZ PF18439.1 RUS83457.1 - 2.3 7.9 9.4 2 8.1 0.2 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS83457.1 - 4.4 7.8 15.7 13 6.4 0.1 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 RUS83457.1 - 4.8 6.9 15.1 0.17 11.6 0.6 3.6 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 RUS83457.1 - 5 6.2 8.6 5.4 6.1 2.3 2.9 1 1 1 2 2 2 0 Putative actin-like family RNA_POL_M_15KD PF02150.16 RUS83457.1 - 6.8 6.7 14.2 5.4 7.0 0.0 4.4 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit Serinc PF03348.15 RUS83458.1 - 2.2e-173 577.1 16.2 2.5e-173 576.9 16.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3278 PF11683.8 RUS83458.1 - 0.0018 18.3 15.1 0.14 12.3 0.4 4.5 3 1 2 5 5 5 3 Protein of unknown function (DUF3278) WD40 PF00400.32 RUS83459.1 - 4.5e-52 172.9 4.5 5.9e-07 30.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83459.1 - 1.3e-14 54.3 0.0 0.0063 16.8 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS83459.1 - 1.4e-08 34.1 0.3 0.075 12.0 0.0 4.9 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS83459.1 - 1.6e-06 28.2 0.0 0.013 15.4 0.0 3.3 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RUS83459.1 - 0.0026 17.6 0.3 1.9 8.5 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 RUS83459.1 - 0.0042 15.8 2.9 1.1 7.8 0.0 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 RUS83459.1 - 2.2 8.0 3.8 9.6 6.0 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Sulfotransfer_2 PF03567.14 RUS83460.1 - 3.7e-22 79.5 0.5 5.1e-22 79.0 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase family TGFb_propeptide PF00688.18 RUS83462.1 - 2.5e-48 165.0 0.0 3.2e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 RUS83462.1 - 3.7e-30 105.0 0.1 6.7e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain SNF PF00209.18 RUS83463.1 - 3.1e-44 151.6 22.4 7.2e-24 84.4 12.1 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Na_Ala_symp PF01235.17 RUS83463.1 - 1.8 7.8 12.4 0.18 11.0 7.6 1.8 2 1 0 2 2 2 0 Sodium:alanine symporter family DUF2798 PF11391.8 RUS83464.1 - 0.15 12.1 37.4 0.81 9.8 12.9 5.0 1 1 2 4 4 4 0 Protein of unknown function (DUF2798) Abhydrolase_9_N PF15420.6 RUS83464.1 - 9.1 6.2 18.3 1.9 8.4 11.2 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus CcmH PF03918.14 RUS83465.1 - 1.7 8.0 3.8 0.4 10.0 0.2 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Fibrinogen_C PF00147.18 RUS83466.1 - 3.4e-49 167.6 3.2 4.4e-48 164.0 3.2 2.0 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS83466.1 - 0.0014 18.7 0.6 0.0021 18.1 0.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 RUS83466.1 - 0.024 13.0 0.2 0.031 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4795 PF16043.5 RUS83466.1 - 0.074 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) WSC PF01822.19 RUS83467.1 - 1.5e-14 53.9 23.9 8.3e-07 29.1 0.7 4.1 3 1 1 4 4 4 3 WSC domain Neurokinin_B PF03823.14 RUS83467.1 - 0.19 11.8 0.7 1.2 9.2 0.0 2.5 1 1 2 3 3 3 0 Neurokinin B Sushi PF00084.20 RUS83467.1 - 2.1 9.0 11.7 0.22 12.2 1.7 2.9 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) DUF4744 PF15918.5 RUS83468.1 - 0.023 15.6 0.0 1.1 10.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) WSC PF01822.19 RUS83469.1 - 2.3e-16 59.7 28.9 8.6e-11 41.9 5.3 3.4 3 0 0 3 3 3 2 WSC domain Sushi PF00084.20 RUS83469.1 - 5.9e-08 33.2 8.6 0.00011 22.7 1.3 2.8 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 RUS83470.1 - 7.6e-21 74.5 35.4 3e-05 24.5 0.9 7.4 6 1 1 7 7 7 7 Sushi repeat (SCR repeat) cEGF PF12662.7 RUS83470.1 - 0.038 13.9 18.2 6.2 6.8 0.4 5.9 5 0 0 5 5 5 0 Complement Clr-like EGF-like MutS_V PF00488.21 RUS83473.1 - 2.2e-73 246.3 0.1 3.8e-73 245.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 RUS83473.1 - 2.9e-35 120.9 0.3 6e-35 119.9 0.3 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 RUS83473.1 - 3e-35 122.2 0.1 7.1e-35 121.0 0.1 1.7 1 0 0 1 1 1 1 MutS domain III PWWP PF00855.17 RUS83473.1 - 2.6e-18 66.2 1.1 8.6e-18 64.5 0.3 2.4 2 0 0 2 2 2 1 PWWP domain MutS_IV PF05190.18 RUS83473.1 - 2.3e-16 59.9 0.1 5.4e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 RUS83473.1 - 1.9e-13 50.9 0.0 6.2e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 MutS domain II LPD30 PF18850.1 RUS83473.1 - 0.16 11.7 0.1 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 Dicty_REP PF05086.12 RUS83473.1 - 2.9 5.7 8.3 4.6 5.1 8.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Choline_transpo PF04515.12 RUS83474.1 - 6.7e-86 288.5 22.3 6.7e-86 288.5 22.3 3.6 3 1 1 4 4 4 2 Plasma-membrane choline transporter TMEM138 PF14935.6 RUS83476.1 - 0.76 10.4 17.9 29 5.4 2.0 4.1 1 1 3 4 4 4 0 Transmembrane protein 138 FAD_binding_2 PF00890.24 RUS83478.1 - 4.2e-121 404.9 0.9 5.4e-121 404.6 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RUS83478.1 - 1.1e-41 141.8 0.1 1.6e-41 141.3 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 RUS83478.1 - 0.04 13.0 0.2 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyridoxal_deC PF00282.19 RUS83479.1 - 1.5e-17 63.4 0.2 1e-16 60.6 0.2 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RUS83479.1 - 3.1e-11 42.9 0.0 1.1e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RUS83479.1 - 0.00084 18.8 0.8 0.0015 17.9 0.2 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 RUS83479.1 - 0.0085 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RUS83479.1 - 0.057 11.9 0.0 3.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF2198 PF09964.9 RUS83480.1 - 0.14 12.2 2.4 0.56 10.3 2.3 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) 7tm_1 PF00001.21 RUS83480.1 - 0.33 10.2 13.6 0.97 8.7 13.5 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF805 PF05656.14 RUS83480.1 - 9.9 6.6 7.5 30 5.1 7.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) VWD PF00094.25 RUS83481.1 - 5.7e-13 49.4 0.0 1.3e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain cEGF PF12662.7 RUS83481.1 - 6.8e-09 35.5 11.7 4.8e-06 26.4 5.0 4.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS83481.1 - 4.2e-08 33.3 10.3 4.2e-08 33.3 10.3 4.7 3 1 1 4 4 4 2 Calcium-binding EGF domain NIDO PF06119.14 RUS83481.1 - 4.6e-07 30.7 0.3 4.6e-07 30.7 0.3 2.3 2 0 0 2 2 2 1 Nidogen-like EGF_3 PF12947.7 RUS83481.1 - 0.0026 17.9 13.4 0.0026 17.9 13.4 3.5 4 1 0 4 4 4 1 EGF domain EGF PF00008.27 RUS83481.1 - 0.012 15.9 6.7 0.012 15.9 6.7 3.9 3 0 0 3 3 3 0 EGF-like domain SR-25 PF10500.9 RUS83481.1 - 0.82 9.2 30.1 1.4 8.5 30.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein hEGF PF12661.7 RUS83481.1 - 9.2 7.1 23.4 0.26 12.0 6.1 4.4 3 1 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.15 RUS83482.1 - 8.8e-29 99.4 76.5 2.7e-10 40.3 10.7 10.3 8 2 2 10 10 10 5 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS83482.1 - 2.4e-06 27.7 23.3 0.00018 21.7 5.5 10.7 3 3 6 9 9 9 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 RUS83482.1 - 5.1e-06 26.4 15.4 0.00023 21.1 2.6 9.6 9 1 1 10 10 10 4 MSP1 EGF domain 1 EGF PF00008.27 RUS83482.1 - 7.1e-06 26.2 18.9 7.3e-05 23.0 5.3 10.8 8 3 2 10 10 10 4 EGF-like domain cEGF PF12662.7 RUS83482.1 - 0.0003 20.7 0.5 0.0003 20.7 0.5 11.2 12 0 0 12 12 12 5 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS83482.1 - 0.00088 19.4 35.8 0.003 17.7 5.7 11.5 9 3 1 10 10 10 5 EGF domain SKG6 PF08693.10 RUS83482.1 - 0.0015 17.9 0.5 0.003 16.9 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SEA PF01390.20 RUS83482.1 - 0.0038 17.3 0.1 0.0064 16.6 0.1 1.3 1 0 0 1 1 1 1 SEA domain hEGF PF12661.7 RUS83482.1 - 0.012 16.2 28.2 0.019 15.6 5.4 13.3 15 1 0 15 15 15 0 Human growth factor-like EGF TMEM154 PF15102.6 RUS83482.1 - 0.019 14.8 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family NAD_binding_2 PF03446.15 RUS83483.1 - 5.3e-48 163.2 1.1 8.3e-48 162.5 1.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RUS83483.1 - 8.5e-35 119.6 0.1 1.6e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 RUS83483.1 - 8.4e-06 25.8 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RUS83483.1 - 1.1e-05 25.9 0.2 3.2e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 RUS83483.1 - 1.3e-05 24.6 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 RUS83483.1 - 0.00021 21.0 0.0 0.00052 19.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 RUS83483.1 - 0.0051 16.4 0.1 0.076 12.6 0.0 2.1 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 RUS83483.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 RUS83483.1 - 0.054 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pex26 PF07163.12 RUS83483.1 - 0.15 11.3 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Pex26 protein Bax1-I PF01027.20 RUS83484.1 - 2.5e-13 50.3 35.5 9.2e-07 28.9 0.3 3.0 2 1 0 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 CobD_Cbib PF03186.13 RUS83484.1 - 0.74 9.0 2.9 0.52 9.5 0.8 1.6 1 1 1 2 2 2 0 CobD/Cbib protein LMBR1 PF04791.16 RUS83485.1 - 3.1e-86 290.3 30.6 1e-54 186.4 8.0 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein TFA2_Winged_2 PF18121.1 RUS83485.1 - 0.0035 17.0 0.1 0.0064 16.2 0.1 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 Tiam_CC_Ex PF18385.1 RUS83485.1 - 0.07 13.5 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain RRM_1 PF00076.22 RUS83486.1 - 9.1e-33 111.9 0.2 8.3e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS83486.1 - 0.00073 19.1 0.1 0.004 16.8 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS83486.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif UL42 PF17638.2 RUS83486.1 - 7.3 6.6 10.3 19 5.3 10.3 1.7 1 0 0 1 1 1 0 HCMV UL42 PID PF00640.23 RUS83487.1 - 0.00074 19.6 0.0 0.00095 19.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) tRNA-synt_1 PF00133.22 RUS83487.1 - 0.0071 14.6 0.0 0.008 14.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) PID_2 PF14719.6 RUS83487.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 RUS83488.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) tRNA-synt_1 PF00133.22 RUS83488.1 - 0.065 11.5 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Ndc1_Nup PF09531.10 RUS83488.1 - 3.9 6.0 7.5 5.2 5.6 7.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Thg1 PF04446.12 RUS83489.1 - 8.7e-05 22.6 2.4 8.7 6.4 2.0 5.2 1 1 1 2 2 2 1 tRNAHis guanylyltransferase PEX-1N PF09262.11 RUS83489.1 - 1.1 9.7 7.9 21 5.6 0.2 3.7 1 1 2 4 4 4 0 Peroxisome biogenesis factor 1, N-terminal SH3_14 PF18343.1 RUS83491.1 - 0.0019 18.3 0.5 0.004 17.3 0.2 1.6 2 0 0 2 2 2 1 Dda helicase SH3 domain Abi_2 PF07751.11 RUS83491.1 - 0.016 15.4 0.8 0.051 13.8 0.5 1.8 2 0 0 2 2 2 0 Abi-like protein RhoGEF PF00621.20 RUS83491.1 - 0.028 14.6 0.7 0.044 14.0 0.7 1.3 1 0 0 1 1 1 0 RhoGEF domain Secretin_N_2 PF07655.13 RUS83491.1 - 0.044 14.3 1.8 0.14 12.7 1.8 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain DHHA1 PF02272.19 RUS83491.1 - 1 9.8 4.5 5.4 7.4 0.7 2.2 1 1 1 2 2 2 0 DHHA1 domain MgtE_N PF03448.17 RUS83491.1 - 1.2 9.8 8.3 0.45 11.2 2.0 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain Bax1-I PF01027.20 RUS83492.1 - 1.1e-27 97.3 37.1 1.3e-27 97.0 37.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SUIM_assoc PF16619.5 RUS83492.1 - 0.018 15.1 4.7 0.032 14.3 4.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4022 PF13214.6 RUS83492.1 - 0.96 9.8 15.2 0.82 10.0 3.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4022) Ig_2 PF13895.6 RUS83493.1 - 1.6e-12 47.6 13.1 0.0099 16.2 1.1 5.1 4 1 1 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.6 RUS83493.1 - 2.3e-11 44.1 10.9 0.019 15.6 0.1 5.2 5 0 0 5 5 5 4 Immunoglobulin domain SprB PF13573.6 RUS83493.1 - 0.0003 20.5 14.4 0.1 12.4 1.6 4.8 4 0 0 4 4 4 2 SprB repeat C1-set PF07654.15 RUS83493.1 - 0.0051 17.1 0.2 0.58 10.6 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ig PF00047.25 RUS83493.1 - 0.055 13.6 9.9 8 6.7 0.1 5.1 5 2 0 5 5 5 0 Immunoglobulin domain Ly49 PF08391.10 RUS83493.1 - 0.19 12.1 0.2 0.39 11.1 0.2 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Peptidase_M56 PF05569.11 RUS83493.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Gal-3-0_sulfotr PF06990.11 RUS83494.1 - 4.8e-41 141.0 0.8 5.7e-41 140.7 0.8 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS83494.1 - 0.024 14.5 0.3 0.049 13.5 0.3 1.5 1 1 0 1 1 1 0 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 RUS83495.1 - 3.8e-47 161.1 0.1 4.9e-47 160.7 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS83495.1 - 0.0008 19.4 0.3 0.0019 18.2 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase family GAGBD PF16828.5 RUS83495.1 - 0.039 14.1 0.1 0.25 11.5 0.0 2.3 2 1 1 3 3 3 0 GAG-binding domain on surface antigen Gal-3-0_sulfotr PF06990.11 RUS83496.1 - 1.7e-47 162.2 1.0 2.7e-47 161.5 1.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase PPIP5K2_N PF18086.1 RUS83496.1 - 0.0074 16.4 0.5 1.1 9.5 0.1 2.6 2 0 0 2 2 2 2 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Sulfotransfer_2 PF03567.14 RUS83496.1 - 0.021 14.8 0.1 0.048 13.6 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase family Trypan_PARP PF05887.11 RUS83497.1 - 0.0091 16.0 10.7 0.032 14.2 10.7 1.9 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PMP1_2 PF08114.11 RUS83497.1 - 0.044 13.5 2.0 0.092 12.5 2.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Orf78 PF06024.12 RUS83497.1 - 5.1 7.5 0.0 5.1 7.5 0.0 3.8 4 1 0 4 4 4 0 Orf78 (ac78) Acyl-ACP_TE PF01643.17 RUS83498.1 - 2.5e-07 30.2 0.0 8.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Acyl-ACP thioesterase Homeodomain PF00046.29 RUS83499.1 - 1.3e-23 82.5 3.9 2.1e-23 81.9 3.9 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS83499.1 - 0.015 15.2 1.7 0.033 14.1 0.4 2.0 2 0 0 2 2 2 0 Homeobox KN domain TFIIA PF03153.13 RUS83501.1 - 0.59 10.1 24.3 0.84 9.6 24.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_48 PF17906.1 RUS83502.1 - 3.2e-09 36.8 0.1 9.5e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 HTH domain in Mos1 transposase HTH_Tnp_Tc3_2 PF01498.18 RUS83502.1 - 1.4e-05 25.3 0.6 3.4e-05 24.0 0.2 1.8 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 RUS83502.1 - 0.00014 22.4 1.5 0.00066 20.2 0.1 2.8 2 1 1 3 3 3 1 Homeodomain-like domain DUF977 PF06163.11 RUS83502.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) HTH_23 PF13384.6 RUS83502.1 - 0.022 14.5 1.8 3.9 7.4 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain DUF4817 PF16087.5 RUS83502.1 - 0.023 14.5 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_24 PF13412.6 RUS83502.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PCI PF01399.27 RUS83502.1 - 0.028 14.9 0.0 0.064 13.8 0.0 1.7 1 1 0 1 1 1 0 PCI domain HTH_26 PF13443.6 RUS83502.1 - 0.043 14.2 0.1 0.084 13.3 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain THEG4 PF15834.5 RUS83502.1 - 0.059 13.4 0.1 0.078 13.0 0.1 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 HTH_Tnp_ISL3 PF13542.6 RUS83502.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_25 PF13413.6 RUS83502.1 - 0.56 10.1 0.1 0.56 10.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAS_11 PF14598.6 RUS83503.1 - 0.019 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 PAS domain Peptidase_M2 PF01401.18 RUS83506.1 - 7.5e-126 421.0 0.4 8.4e-126 420.9 0.4 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M3 PF01432.20 RUS83506.1 - 0.072 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M3 RGM_C PF06534.13 RUS83506.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Peptidase_M2 PF01401.18 RUS83507.1 - 2.7e-06 26.3 0.5 3.4e-06 26.0 0.5 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme zf-CCHC PF00098.23 RUS83508.1 - 3.4e-09 36.4 6.4 8.3e-07 28.8 0.6 3.7 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_6 PF15288.6 RUS83508.1 - 0.0034 17.2 1.4 0.0034 17.2 1.4 3.1 4 0 0 4 4 4 1 Zinc knuckle Asp_protease_2 PF13650.6 RUS83508.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_4 PF14392.6 RUS83508.1 - 0.15 11.9 12.3 0.32 10.8 0.4 3.0 3 0 0 3 3 3 0 Zinc knuckle DUF3367 PF11847.8 RUS83508.1 - 0.21 9.4 0.0 0.29 9.0 0.0 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase zf-C2H2_10 PF16588.5 RUS83508.1 - 0.3 10.9 7.3 0.8 9.5 1.1 2.8 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 RUS83508.1 - 0.52 10.1 14.3 0.96 9.2 0.4 3.5 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger 7tm_1 PF00001.21 RUS83509.1 - 1.4e-15 57.4 13.6 1.4e-15 57.4 12.7 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS83509.1 - 8.7e-10 38.4 4.4 5.6e-09 35.7 4.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS83509.1 - 2.7e-05 23.7 7.0 2.7e-05 23.7 7.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS83509.1 - 0.035 13.7 12.2 0.039 13.6 10.1 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Neur_chan_LBD PF02931.23 RUS83513.1 - 5.9e-46 156.6 0.9 6.7e-46 156.5 0.9 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain p450 PF00067.22 RUS83514.1 - 5.9e-85 285.7 0.2 2.6e-83 280.3 0.2 2.1 1 1 0 1 1 1 1 Cytochrome P450 IBR PF01485.21 RUS83515.1 - 1.5e-19 70.0 42.5 1.8e-13 50.5 8.6 4.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 RUS83515.1 - 0.0037 17.1 14.3 0.0037 17.1 14.3 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS83515.1 - 0.0094 15.9 13.3 0.0094 15.9 13.3 4.3 3 1 0 3 3 3 1 zinc-RING finger domain YTH PF04146.15 RUS83516.1 - 8.3e-45 152.7 0.1 2.5e-44 151.1 0.1 1.9 1 0 0 1 1 1 1 YT521-B-like domain SMN PF06003.12 RUS83517.1 - 1.8e-10 40.6 4.6 4.7e-10 39.2 4.4 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 RUS83517.1 - 0.0027 17.7 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 2 1 Tudor domain DUF4537 PF15057.6 RUS83517.1 - 0.0085 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 4F5 PF04419.14 RUS83517.1 - 0.057 14.3 6.1 0.057 14.3 6.1 1.9 2 0 0 2 2 2 0 4F5 protein family EMC3_TMCO1 PF01956.16 RUS83517.1 - 4.2 7.1 7.0 2.7 7.7 5.2 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Fibrinogen_C PF00147.18 RUS83520.1 - 3.3e-50 170.9 9.0 3.9e-50 170.7 9.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Claudin_2 PF13903.6 RUS83521.1 - 2.9e-15 56.5 10.7 3.9e-15 56.1 10.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS83521.1 - 1.5e-06 28.2 4.1 0.00063 19.7 3.8 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RUS83521.1 - 0.0022 17.9 13.0 0.014 15.4 13.0 1.9 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF423 PF04241.15 RUS83521.1 - 0.066 13.4 5.1 0.12 12.6 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF3040 PF11239.8 RUS83521.1 - 2 8.7 0.0 2 8.7 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) DUF202 PF02656.15 RUS83521.1 - 5.4 7.5 13.4 8.1 7.0 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NKAIN PF05640.14 RUS83522.1 - 9.7e-64 214.4 5.8 1.4e-63 213.9 5.8 1.2 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein CD20 PF04103.15 RUS83522.1 - 0.1 12.7 6.3 0.36 10.9 2.1 2.6 2 1 0 2 2 2 0 CD20-like family DUF3520 PF12034.8 RUS83522.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) TIR_2 PF13676.6 RUS83523.1 - 6e-22 78.5 0.0 1.1e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 RUS83523.1 - 0.0087 16.1 1.1 0.02 15.0 0.3 2.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 RUS83523.1 - 0.034 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H TIR PF01582.20 RUS83523.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 TIR domain DHHC PF01529.20 RUS83524.1 - 4e-50 169.4 26.2 3.9e-25 88.5 13.2 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF2456 PF10445.9 RUS83524.1 - 5.2 7.2 9.9 1.2 9.2 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2456) Methyltransf_22 PF13383.6 RUS83525.1 - 2.3e-10 40.5 0.1 3e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain MHC2-interact PF09307.10 RUS83526.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting UPF0160 PF03690.13 RUS83526.1 - 0.061 12.9 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Methyltransf_22 PF13383.6 RUS83527.1 - 6.9e-24 84.8 1.3 9e-24 84.4 1.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS83527.1 - 8e-05 22.7 0.1 0.00018 21.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain Coilin_N PF15862.5 RUS83527.1 - 0.0027 17.5 2.9 0.0027 17.5 2.9 1.3 1 0 0 1 1 1 1 Coilin N-terminus PGA2 PF07543.12 RUS83527.1 - 0.042 13.8 11.5 0.068 13.2 11.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DARPP-32 PF05395.12 RUS83527.1 - 0.072 13.3 15.5 0.12 12.6 15.5 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 PF06459.12 RUS83527.1 - 0.18 11.6 11.8 0.2 11.4 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI3K_1B_p101 PF10486.9 RUS83527.1 - 0.18 9.6 6.6 0.2 9.4 6.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GFO_IDH_MocA_C PF02894.17 RUS83527.1 - 0.2 11.6 1.8 0.51 10.4 0.0 2.5 3 1 1 4 4 4 0 Oxidoreductase family, C-terminal alpha/beta domain Radial_spoke PF04712.12 RUS83527.1 - 0.49 9.3 17.0 0.84 8.5 17.0 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein DUF913 PF06025.12 RUS83527.1 - 0.86 8.5 3.1 1 8.3 3.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RUS83527.1 - 1.2 7.8 4.3 1.2 7.9 4.3 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 RUS83527.1 - 1.5 9.2 7.6 2.1 8.8 7.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CoA_transf_3 PF02515.17 RUS83528.1 - 1.4e-70 238.3 0.0 1.7e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III PrmA PF06325.13 RUS83529.1 - 5.7e-11 42.3 0.1 8.9e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RUS83529.1 - 1e-09 38.2 0.1 1.8e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RUS83529.1 - 6.8e-08 33.1 0.2 4.6e-07 30.4 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS83529.1 - 7.2e-08 32.3 0.0 9.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 RUS83529.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RUS83529.1 - 2e-05 24.3 0.1 0.00013 21.6 0.0 1.9 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 RUS83529.1 - 0.0002 21.1 0.0 0.00064 19.5 0.0 1.8 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 RUS83529.1 - 0.00027 21.6 0.1 0.0015 19.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 RUS83529.1 - 0.0017 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PCMT PF01135.19 RUS83529.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6-adenineMlase PF10237.9 RUS83529.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_10 PF05971.12 RUS83529.1 - 0.042 13.2 0.0 0.089 12.1 0.0 1.5 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_32 PF13679.6 RUS83529.1 - 0.063 13.3 0.0 0.082 12.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RUS83529.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF1759 PF03564.15 RUS83530.1 - 9.6e-10 38.6 0.3 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) HVSL PF09749.9 RUS83530.1 - 0.012 15.1 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein RVT_1 PF00078.27 RUS83530.1 - 0.044 13.3 0.1 0.088 12.3 0.1 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cpta_toxin PF07254.12 RUS83530.1 - 0.076 13.0 0.4 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system SEP PF08059.13 RUS83533.1 - 6.6e-17 61.9 0.0 1.6e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 SEP domain LRR_4 PF12799.7 RUS83534.1 - 1.4e-11 44.4 0.1 3e-05 24.3 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS83534.1 - 4.3e-08 32.9 0.1 0.00022 20.8 0.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RUS83534.1 - 3.1e-05 23.6 2.7 0.011 15.4 1.1 2.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 RUS83534.1 - 0.011 15.8 0.3 10 6.5 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat MAPEG PF01124.18 RUS83535.1 - 7.6e-05 22.6 1.9 0.00011 22.1 1.5 1.5 1 1 0 1 1 1 1 MAPEG family Lectin_C PF00059.21 RUS83536.1 - 2.8e-13 50.5 0.2 3.9e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS83537.1 - 3.1e-09 37.5 0.5 3.1e-09 37.5 0.5 2.0 2 0 0 2 2 2 1 Lectin C-type domain LapA_dom PF06305.11 RUS83537.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Aft1_HRA PF11786.8 RUS83538.1 - 0.011 16.1 0.1 9.6 6.6 0.0 3.3 1 1 2 3 3 3 0 Aft1 HRA domain LMWPc PF01451.21 RUS83538.1 - 0.17 12.3 3.7 37 4.7 0.1 4.5 3 2 1 4 4 4 0 Low molecular weight phosphotyrosine protein phosphatase GTP_EFTU PF00009.27 RUS83539.1 - 1.3e-53 181.5 0.0 2.1e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RUS83539.1 - 4.6e-40 136.4 0.1 1e-39 135.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RUS83539.1 - 7.3e-15 55.1 2.3 1e-14 54.7 0.5 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RUS83539.1 - 0.00011 22.2 0.1 0.0035 17.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 RUS83539.1 - 0.0029 17.5 1.0 0.007 16.3 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Dynamin_N PF00350.23 RUS83539.1 - 0.022 14.8 0.0 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Gtr1_RagA PF04670.12 RUS83539.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 RUS83539.1 - 0.16 11.5 0.2 7 6.2 0.0 3.2 4 0 0 4 4 4 0 Ferrous iron transport protein B WD40 PF00400.32 RUS83540.1 - 2.6e-44 148.3 16.7 2.6e-09 37.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83540.1 - 9.9e-12 45.0 0.0 2.8e-05 24.3 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS83540.1 - 0.0014 17.3 2.5 0.016 13.9 0.6 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS83540.1 - 0.0051 15.8 0.0 1.6 7.6 0.0 3.1 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RUS83540.1 - 0.04 13.2 0.0 3.3 7.0 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 RUS83540.1 - 0.048 12.4 0.0 0.77 8.4 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like Pox_TAP PF03355.14 RUS83540.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Viral Trans-Activator Protein 14-3-3 PF00244.20 RUS83541.1 - 3.3e-155 514.0 25.1 3.3e-95 317.8 13.0 2.0 1 1 1 2 2 2 2 14-3-3 protein AgI_II_C2 PF17998.1 RUS83541.1 - 1.1e-05 25.8 6.5 0.032 14.6 0.9 2.4 2 0 0 2 2 2 2 Cell surface antigen I/II C2 terminal domain HBM PF16591.5 RUS83541.1 - 1.5e-05 24.5 2.6 0.16 11.4 0.0 3.2 3 0 0 3 3 3 2 Helical bimodular sensor domain DUF4786 PF16027.5 RUS83541.1 - 0.00089 19.9 0.3 2.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4786) MqsA_antitoxin PF15731.5 RUS83541.1 - 0.0011 19.1 0.1 3.3 7.8 0.0 3.0 3 0 0 3 3 3 2 Antitoxin component of bacterial toxin-antitoxin system, MqsA FlaF PF07309.11 RUS83541.1 - 0.0018 18.2 3.6 0.11 12.5 0.4 2.7 2 0 0 2 2 2 1 Flagellar protein FlaF EpoR_lig-bind PF09067.10 RUS83541.1 - 0.0076 16.4 0.1 7.5 6.8 0.0 2.6 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding RAD51_interact PF15696.5 RUS83541.1 - 0.01 15.9 0.1 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 RAD51 interacting motif TadF PF16964.5 RUS83541.1 - 0.055 13.2 8.2 1.4 8.7 1.5 2.4 2 0 0 2 2 2 0 Putative tight adherence pilin protein F Med21 PF11221.8 RUS83541.1 - 0.073 13.3 0.1 0.073 13.3 0.1 2.5 3 1 0 3 3 3 0 Subunit 21 of Mediator complex Ribosomal_L22 PF00237.19 RUS83541.1 - 0.08 13.2 4.3 8.6 6.7 0.2 3.4 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e Ta0938 PF11494.8 RUS83541.1 - 0.18 12.1 0.9 3 8.2 0.1 2.4 2 0 0 2 2 2 0 Ta0938 TPR_19 PF14559.6 RUS83541.1 - 0.28 11.7 5.0 14 6.2 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TipE PF16972.5 RUS83541.1 - 0.29 10.3 5.6 4 6.5 0.5 2.3 1 1 0 2 2 2 0 Na+ channel auxiliary subunit TipE Acyl-CoA_dh_C PF12806.7 RUS83541.1 - 0.33 11.1 3.1 0.36 11.0 0.1 2.6 3 1 1 4 4 4 0 Acetyl-CoA dehydrogenase C-terminal like B2-adapt-app_C PF09066.10 RUS83541.1 - 2.2 8.4 5.2 2.7 8.1 0.3 2.7 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain Phage_holin_6_1 PF09682.10 RUS83541.1 - 4.5 7.7 8.7 21 5.6 0.4 4.1 4 0 0 4 4 4 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ima1_N PF09779.9 RUS83541.1 - 7.8 7.4 7.2 4.2 8.2 0.4 3.2 2 1 1 3 3 3 0 Ima1 N-terminal domain RL10P_insert PF17777.1 RUS83542.1 - 5.6e-26 90.3 0.2 9.3e-26 89.6 0.2 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RUS83542.1 - 7.9e-22 77.3 0.2 1.2e-21 76.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF349 PF03993.12 RUS83542.1 - 0.0098 16.2 1.7 0.026 14.8 1.7 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) Pkinase PF00069.25 RUS83543.1 - 5.6e-09 35.7 3.1 9e-09 35.1 3.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83543.1 - 0.0011 18.4 0.5 0.0016 17.8 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UPF0054 PF02130.17 RUS83543.1 - 0.006 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 zf-C2H2 PF00096.26 RUS83544.1 - 5.2e-07 29.8 24.9 0.0029 18.0 7.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type NOA36 PF06524.12 RUS83544.1 - 0.00011 21.6 7.0 0.00021 20.7 7.0 1.4 1 0 0 1 1 1 1 NOA36 protein zf-H2C2_2 PF13465.6 RUS83544.1 - 0.0017 18.7 7.0 0.0017 18.7 7.0 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS83544.1 - 0.012 16.4 19.9 0.042 14.7 4.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 RUS83544.1 - 0.039 14.3 20.6 0.65 10.5 3.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS83544.1 - 0.52 10.7 20.8 0.1 12.9 6.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS83544.1 - 1.3 9.4 15.0 0.29 11.5 6.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RUS83544.1 - 2.9 8.4 14.4 0.27 11.7 3.4 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RUS83544.1 - 4.5 7.0 8.8 16 5.3 1.0 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 RUS83546.1 - 3.8e-10 39.7 9.2 0.0031 18.2 0.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS83546.1 - 4.4e-10 39.6 0.6 0.016 15.5 0.0 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS83546.1 - 5.8e-09 35.9 11.2 0.012 16.0 1.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS83546.1 - 4.8e-06 26.8 4.7 0.045 14.2 0.0 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 RUS83546.1 - 0.003 17.9 11.3 0.35 11.3 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS83546.1 - 0.034 14.5 7.7 4.2 7.8 0.1 4.5 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) TFIIA PF03153.13 RUS83546.1 - 0.2 11.6 32.6 0.44 10.5 32.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_3rep PF18868.1 RUS83546.1 - 0.29 11.8 6.7 0.22 12.2 1.3 3.2 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 RUS83546.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 RUS83546.1 - 2.7 8.3 6.7 6.3 7.2 1.7 3.0 1 1 2 3 3 3 0 C2H2-type zinc ribbon Phosducin PF02114.16 RUS83547.1 - 1.3e-18 67.0 0.1 1.4e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin iPGM_N PF06415.13 RUS83547.1 - 0.095 12.2 5.5 0.16 11.4 5.5 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) 7tm_1 PF00001.21 RUS83550.1 - 1.5e-25 90.0 0.7 2e-25 89.6 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS83550.1 - 0.00096 19.0 1.1 0.00096 19.0 1.1 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS83550.1 - 0.0017 17.8 8.1 0.0042 16.5 2.3 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx LapA_dom PF06305.11 RUS83550.1 - 0.1 12.5 0.4 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 RUS83552.1 - 2.5e-23 82.8 0.0 6.1e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83552.1 - 6.3e-16 58.4 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS83552.1 - 5.5e-05 23.2 0.8 5.5e-05 23.2 0.8 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS83552.1 - 0.0065 15.3 1.3 0.011 14.6 0.1 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 RUS83552.1 - 0.021 14.2 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS83552.1 - 0.06 12.9 0.7 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 RUS83552.1 - 0.063 12.2 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 RUS83554.1 - 1.3e-23 83.7 0.0 2.5e-23 82.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83554.1 - 5.4e-16 58.6 0.0 1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS83554.1 - 5.8e-05 23.1 0.8 5.8e-05 23.1 0.8 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS83554.1 - 0.0045 15.8 0.1 0.013 14.3 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RUS83554.1 - 0.021 14.2 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS83554.1 - 0.043 13.4 0.7 0.065 12.8 0.1 1.5 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 RUS83554.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase COesterase PF00135.28 RUS83556.1 - 2.3e-234 779.0 0.0 7.1e-132 440.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS83556.1 - 5.8e-20 72.1 0.1 1.6e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold GPAT_N PF14829.6 RUS83556.1 - 0.00082 19.3 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Glycerol-3-phosphate acyltransferase N-terminal Totivirus_coat PF05518.11 RUS83556.1 - 0.043 11.9 0.0 5.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Totivirus coat protein DUF2162 PF09930.9 RUS83556.1 - 0.059 12.8 0.3 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Predicted transporter (DUF2162) DUF742 PF05331.11 RUS83556.1 - 0.06 13.2 0.1 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) CSTF_C PF14304.6 RUS83556.1 - 0.098 12.3 0.7 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Terminase_1 PF03354.15 RUS83556.1 - 0.11 11.1 0.0 11 4.4 0.0 2.1 2 0 0 2 2 2 0 Phage Terminase DUF3293 PF11697.8 RUS83556.1 - 0.26 11.8 0.8 34 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) Gal-3-0_sulfotr PF06990.11 RUS83557.1 - 1.8e-52 178.6 1.4 2.5e-52 178.1 1.4 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS83557.1 - 3.8e-05 23.7 0.2 9.5e-05 22.4 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase family PPIP5K2_N PF18086.1 RUS83557.1 - 0.0007 19.7 0.5 0.76 10.0 0.1 2.8 2 0 0 2 2 2 2 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain p450 PF00067.22 RUS83558.1 - 3.3e-107 359.1 0.0 3.8e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GcrA PF07750.11 RUS83559.1 - 0.051 14.0 4.5 0.1 13.0 4.3 1.5 2 0 0 2 2 2 0 GcrA cell cycle regulator MAJIN PF15077.6 RUS83559.1 - 0.64 9.8 2.8 0.92 9.2 2.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Forkhead PF00250.18 RUS83560.1 - 2.6e-25 88.5 0.6 1.2e-24 86.4 0.6 2.2 1 0 0 1 1 1 1 Forkhead domain HNOBA PF07701.14 RUS83561.1 - 6.8e-71 238.2 3.0 1.2e-70 237.4 3.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 RUS83561.1 - 2e-49 167.7 0.1 3.1e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 RUS83561.1 - 7.5e-33 113.7 1.1 1.6e-31 109.4 1.1 2.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CDC45 PF02724.14 RUS83561.1 - 2.2 6.4 11.7 3.1 6.0 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 RUS83561.1 - 5.8 6.4 7.4 11 5.5 7.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 RUS83561.1 - 5.9 6.6 9.3 11 5.8 9.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Guanylate_cyc PF00211.20 RUS83562.1 - 2.5e-50 170.7 0.4 4.8e-23 81.7 0.0 3.5 2 1 1 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 RUS83562.1 - 5e-40 137.7 0.9 2.7e-34 118.9 0.2 2.3 1 1 1 2 2 2 2 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS83562.1 - 8.3e-28 97.4 0.1 4.2e-19 68.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS83562.1 - 3.1e-24 85.8 0.0 1.9e-18 66.8 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain RVT_1 PF00078.27 RUS83562.1 - 2.7e-07 30.4 0.0 6.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNOBA PF07701.14 RUS83562.1 - 7.7e-06 25.5 1.5 1.9e-05 24.2 1.5 1.7 1 0 0 1 1 1 1 Heme NO binding associated Dynein_AAA_lid PF17852.1 RUS83562.1 - 0.013 15.6 0.9 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain CENP-B_dimeris PF09026.10 RUS83562.1 - 0.044 14.2 18.9 0.11 12.9 18.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Semialdhyde_dh PF01118.24 RUS83563.1 - 0.00078 19.9 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 RUS83563.1 - 0.049 13.7 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 RUS83563.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mob1_phocein PF03637.17 RUS83564.1 - 2.4e-79 265.2 0.2 2.9e-79 265.0 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family 2-oxoacid_dh PF00198.23 RUS83566.1 - 2.6e-63 213.6 0.1 3.5e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RUS83566.1 - 2.1e-18 65.9 2.0 9.6e-18 63.8 0.9 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 RUS83566.1 - 2.2e-08 34.3 0.1 1e-07 32.2 0.1 2.3 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RUS83566.1 - 0.00083 19.1 0.0 0.017 14.9 0.0 2.8 3 0 0 3 3 3 1 Biotin-lipoyl like QRPTase_N PF02749.16 RUS83566.1 - 0.03 14.4 0.1 0.16 12.1 0.0 2.2 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Ribosomal_S17_N PF16205.5 RUS83567.1 - 8.6e-34 115.8 0.8 8.6e-34 115.8 0.8 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 RUS83567.1 - 8.5e-26 89.9 1.6 1.3e-25 89.3 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 NDUFV3 PF15880.5 RUS83568.1 - 2e-08 34.1 1.8 3.9e-08 33.2 1.8 1.5 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial AAA PF00004.29 RUS83569.1 - 0.016 15.6 0.3 0.76 10.2 0.0 3.5 4 1 1 5 5 5 0 ATPase family associated with various cellular activities (AAA) THAP PF05485.12 RUS83570.1 - 3.2e-06 28.0 0.7 3.2e-06 28.0 0.7 2.8 3 1 1 4 4 4 1 THAP domain Helitron_like_N PF14214.6 RUS83570.1 - 0.00031 21.0 0.1 0.00062 20.0 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PHD PF00628.29 RUS83570.1 - 0.012 15.4 9.0 0.012 15.4 9.0 2.8 2 1 0 2 2 2 0 PHD-finger GrpE PF01025.19 RUS83570.1 - 0.021 14.5 2.2 0.049 13.3 2.2 1.5 1 0 0 1 1 1 0 GrpE Sugarporin_N PF11471.8 RUS83570.1 - 0.15 12.0 0.9 0.3 11.1 0.9 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Swi5 PF07061.11 RUS83570.1 - 0.88 9.7 4.0 2.1 8.5 4.0 1.6 1 0 0 1 1 1 0 Swi5 Latexin PF06907.12 RUS83571.1 - 0.046 13.2 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Latexin bZIP_1 PF00170.21 RUS83572.1 - 0.0054 16.8 0.9 0.0095 16.0 0.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor Thioredoxin_2 PF13098.6 RUS83572.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain SNF2_N PF00176.23 RUS83574.1 - 2.9e-67 226.9 2.9 6.2e-67 225.8 2.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.13 RUS83574.1 - 1.6e-20 73.1 9.8 1.6e-20 73.1 9.8 6.5 7 1 1 8 8 8 2 HSA Helicase_C PF00271.31 RUS83574.1 - 1.4e-18 67.3 0.0 6.1e-18 65.2 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RUS83574.1 - 0.037 13.2 0.0 0.31 10.1 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 EDR1 PF14381.6 RUS83574.1 - 0.099 12.3 0.4 0.26 11.0 0.4 1.7 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 COX6A PF02046.15 RUS83575.1 - 1.3e-13 51.3 0.3 2.3e-13 50.6 0.3 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa MMR_HSR1 PF01926.23 RUS83576.1 - 1.4e-20 73.5 0.0 3.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS83576.1 - 2.7e-11 43.3 0.1 5e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS83576.1 - 9.8e-08 32.1 1.8 0.0005 20.0 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS83576.1 - 9.2e-07 28.6 0.8 0.0098 15.4 0.0 3.6 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RUS83576.1 - 1.6e-06 28.2 0.1 0.00072 19.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 RUS83576.1 - 1.5e-05 24.4 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 RUS83576.1 - 0.00041 20.8 0.1 0.00068 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain KH_2 PF07650.17 RUS83576.1 - 0.00061 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 KH domain PduV-EutP PF10662.9 RUS83576.1 - 0.0022 17.8 0.0 0.088 12.5 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Tropomodulin PF03250.14 RUS83576.1 - 0.0072 16.4 0.2 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Tropomodulin MeaB PF03308.16 RUS83576.1 - 0.0081 15.2 0.1 0.53 9.2 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 RUS83576.1 - 0.011 15.6 0.1 0.57 9.9 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 RUS83576.1 - 0.045 12.9 0.4 4.4 6.4 0.2 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 RUS83576.1 - 0.068 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 RUS83576.1 - 0.13 12.3 0.1 0.76 9.8 0.1 2.2 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain CDP-OH_P_transf PF01066.21 RUS83577.1 - 1.1e-12 48.5 0.3 1.9e-12 47.7 0.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ANF_receptor PF01094.28 RUS83578.1 - 1.3e-72 244.9 0.0 1.9e-43 149.0 0.0 2.9 3 0 0 3 3 3 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS83578.1 - 4e-15 56.3 0.3 6.2e-07 29.4 0.2 3.4 3 1 0 3 3 3 2 Periplasmic binding protein ANF_receptor PF01094.28 RUS83579.1 - 1e-16 61.0 0.0 1.3e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 RUS83580.1 - 7.3e-32 111.0 22.2 1.1e-31 110.5 22.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4064 PF13273.6 RUS83580.1 - 0.052 13.8 0.0 0.052 13.8 0.0 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) TMEM208_SND2 PF05620.11 RUS83580.1 - 2.2 8.0 10.2 4.2 7.1 1.0 3.2 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Phage_holin_5_2 PF16079.5 RUS83580.1 - 8 6.9 12.1 14 6.0 3.3 3.1 2 2 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V bZIP_2 PF07716.15 RUS83581.1 - 1.6e-10 40.9 16.7 1.8e-10 40.7 14.6 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS83581.1 - 3.7e-10 39.8 16.8 3.7e-10 39.8 16.8 2.8 2 1 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 RUS83581.1 - 2.5e-06 27.9 9.3 4.9e-06 27.0 8.9 1.8 1 1 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 RUS83581.1 - 0.0027 18.1 5.5 0.0054 17.1 5.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB TSC22 PF01166.18 RUS83581.1 - 0.017 15.4 7.3 0.036 14.4 2.1 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 RUS83581.1 - 0.03 14.5 4.8 0.075 13.2 4.7 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TMCO5 PF14992.6 RUS83581.1 - 0.031 13.9 5.3 0.042 13.4 5.3 1.2 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.19 RUS83581.1 - 0.038 11.9 1.1 0.043 11.7 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RTBV_P46 PF06216.11 RUS83581.1 - 0.067 12.1 0.5 0.084 11.7 0.5 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein YabA PF06156.13 RUS83581.1 - 0.17 12.6 8.5 0.043 14.4 4.7 2.0 2 1 1 3 3 2 0 Initiation control protein YabA GvpL_GvpF PF06386.11 RUS83581.1 - 0.19 11.6 2.2 0.26 11.2 2.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CemA PF03040.14 RUS83581.1 - 0.22 11.4 1.0 0.31 11.0 1.0 1.2 1 0 0 1 1 1 0 CemA family Nas2_N PF18265.1 RUS83581.1 - 0.25 11.3 4.8 4.7 7.2 0.1 3.0 1 1 2 3 3 3 0 Nas2 N_terminal domain LCD1 PF09798.9 RUS83581.1 - 0.32 9.5 7.3 0.35 9.3 7.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SOGA PF11365.8 RUS83581.1 - 0.35 12.0 8.6 0.18 13.0 4.1 2.3 1 1 1 2 2 2 0 Protein SOGA Shugoshin_N PF07558.11 RUS83581.1 - 0.44 10.4 7.3 7.7 6.5 0.3 2.7 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region UPF0242 PF06785.11 RUS83581.1 - 2.7 8.1 12.9 32 4.6 12.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Herpes_BLRF2 PF05812.12 RUS83581.1 - 4 7.6 14.9 22 5.2 8.4 3.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein NYD-SP28_assoc PF14775.6 RUS83581.1 - 4.7 7.4 7.8 9.2 6.5 2.3 2.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain Senescence PF06911.12 RUS83582.1 - 1.5e-16 61.3 3.3 5.9e-16 59.3 0.2 2.4 2 0 0 2 2 2 1 Senescence-associated protein KptA_kDCL PF18176.1 RUS83582.1 - 0.012 15.5 0.6 0.033 14.1 0.6 1.7 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Phageshock_PspG PF09583.10 RUS83582.1 - 0.93 9.8 4.5 1.6 9.0 4.5 1.4 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) LIAS_N PF16881.5 RUS83585.1 - 5.1e-31 107.3 0.8 1e-30 106.3 0.8 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 RUS83585.1 - 1.8e-12 47.9 0.0 3.6e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Methyltrans_Mon PF14314.6 RUS83585.1 - 0.1 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase DDE_Tnp_4 PF13359.6 RUS83586.1 - 7.8e-23 80.9 0.0 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS83586.1 - 2.7e-06 27.1 0.0 0.00056 19.6 0.0 2.3 1 1 1 2 2 2 2 Plant transposon protein HTH_Tnp_4 PF13613.6 RUS83586.1 - 0.00095 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Methyltransf_11 PF08241.12 RUS83587.1 - 1.8e-11 44.5 0.0 6.6e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS83587.1 - 6.5e-08 33.2 0.0 1.8e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS83587.1 - 1.9e-06 28.6 0.0 1.2e-05 25.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS83587.1 - 8.9e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS83587.1 - 0.00028 20.8 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS83587.1 - 0.00029 20.2 0.0 0.00087 18.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family LicD PF04991.13 RUS83588.1 - 1.5e-05 25.3 0.2 2.7e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 LicD family DUF1365 PF07103.11 RUS83588.1 - 0.027 14.1 0.2 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) STAT1_TAZ2bind PF12162.8 RUS83588.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Ion_trans PF00520.31 RUS83589.1 - 5.5e-26 91.3 19.4 8e-26 90.8 19.4 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 RUS83589.1 - 1.3e-25 89.6 9.8 3.1e-25 88.3 9.8 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 RUS83589.1 - 1e-19 70.4 0.0 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RUS83589.1 - 0.0035 17.3 6.1 0.016 15.2 6.0 2.3 1 1 0 1 1 1 1 Ion channel PspA_IM30 PF04012.12 RUS83589.1 - 0.0092 15.6 5.7 0.016 14.8 5.7 1.3 1 0 0 1 1 1 1 PspA/IM30 family DUF1043 PF06295.12 RUS83589.1 - 0.051 13.6 3.4 0.22 11.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF948 PF06103.11 RUS83589.1 - 0.087 13.1 4.0 0.61 10.4 1.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RUS83589.1 - 0.1 12.6 1.0 0.84 9.7 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 RUS83589.1 - 0.19 11.1 2.7 0.37 10.1 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 RUS83589.1 - 0.2 11.7 4.4 5.3 7.1 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GvpK PF05121.12 RUS83589.1 - 0.22 11.6 6.4 0.52 10.4 6.4 1.7 1 0 0 1 1 1 0 Gas vesicle protein K CCDC106 PF15794.5 RUS83589.1 - 0.23 11.1 4.8 0.38 10.4 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PTRF_SDPR PF15237.6 RUS83589.1 - 0.23 11.0 5.5 0.085 12.5 2.7 1.6 2 0 0 2 2 2 0 PTRF/SDPR family DUF148 PF02520.17 RUS83589.1 - 0.83 9.8 6.3 1.9 8.6 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Enkurin PF13864.6 RUS83589.1 - 0.84 10.1 6.3 2.3 8.7 6.3 1.7 1 0 0 1 1 1 0 Calmodulin-binding DUF5446 PF17522.2 RUS83589.1 - 1 9.6 3.4 0.63 10.3 0.9 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5446) Tropomyosin PF00261.20 RUS83589.1 - 1.2 8.4 12.5 0.063 12.6 6.6 1.8 2 0 0 2 2 2 0 Tropomyosin Exonuc_VII_L PF02601.15 RUS83589.1 - 1.7 8.1 4.0 0.39 10.2 0.9 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit XhlA PF10779.9 RUS83589.1 - 2.1 8.6 6.1 5.3 7.3 2.6 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Nup54 PF13874.6 RUS83589.1 - 2.2 8.4 6.5 2.3 8.3 2.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4298 PF14131.6 RUS83589.1 - 2.4 8.2 4.9 15 5.6 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4298) WXG100 PF06013.12 RUS83589.1 - 5.8 7.2 7.7 4.2 7.7 3.7 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DDE_1 PF03184.19 RUS83590.1 - 2.4e-10 40.3 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 RUS83591.1 - 0.0022 17.7 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 RUS83591.1 - 0.003 17.7 0.0 0.0079 16.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 RUS83591.1 - 0.0049 16.9 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 RUS83591.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Fasciclin PF02469.22 RUS83592.1 - 1.9e-22 79.9 4.1 6.1e-12 45.9 0.5 2.8 2 1 1 3 3 3 2 Fasciclin domain DUF211 PF02680.14 RUS83592.1 - 0.29 11.3 3.0 1.3 9.3 0.1 2.8 4 0 0 4 4 4 0 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 RUS83593.1 - 1.6e-33 115.6 0.1 5.4e-23 81.6 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain RVT_1 PF00078.27 RUS83594.1 - 1.4e-19 70.5 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4129 PF13559.6 RUS83594.1 - 0.065 13.5 3.9 2.5 8.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) DUF2737 PF10930.8 RUS83594.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) YebO PF13974.6 RUS83594.1 - 0.27 11.3 2.9 0.73 10.0 2.9 1.8 1 0 0 1 1 1 0 YebO-like protein DUF4461 PF14688.6 RUS83594.1 - 0.64 9.7 4.8 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) HrpJ PF07201.11 RUS83594.1 - 2 8.7 10.6 4.5 7.6 6.7 2.4 2 0 0 2 2 2 0 HrpJ-like domain Fasciclin PF02469.22 RUS83595.1 - 4.8e-52 175.5 3.1 1.7e-31 109.1 0.8 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 RUS83595.1 - 0.0061 16.7 0.6 0.26 11.5 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 RUS83597.1 - 2.1e-36 125.0 0.3 1.8e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain GARS_N PF02844.15 RUS83597.1 - 0.12 13.2 0.1 9.8 7.0 0.0 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain gag-asp_proteas PF13975.6 RUS83598.1 - 0.016 15.8 0.0 0.053 14.1 0.0 1.9 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 RUS83598.1 - 0.029 14.7 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease THAP PF05485.12 RUS83599.1 - 1e-07 32.8 0.1 1.7e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 THAP domain DUF4921 PF16268.5 RUS83600.1 - 0.028 13.2 0.6 2.3 6.9 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4921) Nup153 PF08604.10 RUS83601.1 - 6.3e-25 88.0 33.4 6.8e-24 84.5 33.4 2.1 1 1 0 1 1 1 1 Nucleoporin Nup153-like zf-RanBP PF00641.18 RUS83601.1 - 3.9e-21 74.1 12.4 1.7e-10 40.1 3.3 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 RUS83601.1 - 0.084 12.9 9.4 0.15 12.1 9.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Vps36-NZF-N PF16988.5 RUS83601.1 - 0.12 11.8 5.4 4 6.9 0.2 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RT_RNaseH_2 PF17919.1 RUS83602.1 - 1.7e-33 114.6 0.0 3.3e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS83602.1 - 1.4e-32 112.1 0.0 2.7e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS83602.1 - 3.3e-20 72.6 0.0 6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 RUS83602.1 - 0.00017 21.5 8.7 0.00038 20.4 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle MCM PF00493.23 RUS83603.1 - 5.1e-99 329.9 0.0 7.7e-99 329.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RUS83603.1 - 4.3e-38 130.0 0.1 8.4e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS83603.1 - 5.7e-30 103.6 2.4 1.6e-29 102.1 2.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RUS83603.1 - 4.4e-18 65.8 3.5 9.1e-18 64.8 0.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 RUS83603.1 - 9.9e-12 45.4 24.0 9.9e-12 45.4 24.0 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 RUS83603.1 - 1.6e-08 34.2 0.0 1.4e-06 27.8 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RUS83603.1 - 2.1e-06 27.6 0.0 0.00028 20.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS83603.1 - 2.3e-05 24.4 0.0 8.1e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF445 PF04286.12 RUS83603.1 - 0.004 17.0 5.5 0.26 11.0 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF445) AAA_lid_2 PF17863.1 RUS83603.1 - 0.0054 16.6 0.1 0.091 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 RUS83603.1 - 0.0075 16.0 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 RUS83603.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RUS83603.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cyclase PF04199.13 RUS83604.1 - 7.5e-31 107.2 0.0 9.7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Ion_trans PF00520.31 RUS83605.1 - 2.9e-250 825.7 89.3 1.8e-70 237.0 8.3 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 RUS83605.1 - 5.8e-30 103.3 0.0 1.6e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 RUS83605.1 - 5e-29 99.8 0.1 2.3e-28 97.7 0.1 2.2 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated CAC1F_C PF16885.5 RUS83605.1 - 3.9e-15 56.4 2.5 3.9e-15 56.4 2.5 3.1 2 1 0 2 2 2 1 Voltage-gated calcium channel subunit alpha, C-term PKD_channel PF08016.12 RUS83605.1 - 1.9e-12 46.6 79.8 1.5e-06 27.1 1.1 9.8 6 4 3 9 9 9 5 Polycystin cation channel GET2 PF08690.10 RUS83605.1 - 0.037 13.7 0.0 0.037 13.7 0.0 3.3 4 0 0 4 4 4 0 GET complex subunit GET2 AMP-binding PF00501.28 RUS83606.1 - 2.1e-58 197.9 0.1 2.5e-58 197.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L21p PF00829.21 RUS83607.1 - 1.3 9.3 5.1 0.88 9.9 2.6 1.9 2 1 0 2 2 2 0 Ribosomal prokaryotic L21 protein Lipocalin_2 PF08212.12 RUS83608.1 - 7.1e-24 84.4 0.0 8.6e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS83608.1 - 1.4e-14 54.5 0.0 1.6e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family zf-C3H1 PF10650.9 RUS83610.1 - 1.1e-06 28.2 3.3 2.5e-06 27.1 3.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_14 PF13428.6 RUS83610.1 - 0.021 15.6 0.0 80 4.5 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Spond_N PF06468.13 RUS83611.1 - 4.5e-63 212.9 0.1 7e-63 212.2 0.1 1.3 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 RUS83611.1 - 7.7e-31 106.1 33.4 8.1e-11 42.0 11.5 4.1 3 0 0 3 3 3 3 Thrombospondin type 1 domain Kunitz_BPTI PF00014.23 RUS83611.1 - 1.1e-16 60.8 3.7 1.1e-16 60.8 3.7 2.8 3 0 0 3 3 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Reeler PF02014.16 RUS83611.1 - 4.4e-16 59.8 0.0 8.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reeler domain Neur_chan_memb PF02932.16 RUS83612.1 - 0.0002 21.5 4.7 0.0002 21.5 4.7 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS83612.1 - 0.0012 18.4 0.1 0.0028 17.1 0.1 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2070 PF09843.9 RUS83612.1 - 0.082 11.2 10.5 0.11 10.8 10.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4271 PF14093.6 RUS83612.1 - 1.2 9.1 15.3 11 5.9 16.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) ATLF PF07737.11 RUS83613.1 - 0.19 11.0 2.3 5.7 6.2 0.1 2.1 1 1 1 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain Syntaxin-6_N PF09177.11 RUS83613.1 - 0.54 10.8 3.1 0.94 10.1 0.1 2.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal HalX PF08663.10 RUS83613.1 - 2.2 8.7 6.4 0.83 10.0 0.8 2.5 2 0 0 2 2 2 0 HalX domain DUF4692 PF15763.5 RUS83614.1 - 0.67 10.4 5.4 1.1 9.7 5.4 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sporozoite_P67 PF05642.11 RUS83614.1 - 0.72 7.9 8.2 0.78 7.7 8.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 RUS83614.1 - 2.2 7.9 8.4 3.1 7.4 8.4 1.3 1 0 0 1 1 1 0 FAM176 family DDRGK PF09756.9 RUS83614.1 - 6.1 6.4 19.0 8.8 5.9 19.0 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.14 RUS83614.1 - 7.1 4.8 11.8 8.5 4.5 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RUS83614.1 - 9.6 4.9 9.7 12 4.6 9.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Lipase_GDSL PF00657.22 RUS83619.1 - 3.3e-14 53.3 0.0 4.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RUS83619.1 - 4e-09 37.1 0.1 8.4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RUS83620.1 - 6e-15 55.7 0.0 8.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RUS83620.1 - 3e-08 34.3 0.1 4.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 7tm_2 PF00002.24 RUS83621.1 - 1.2e-11 44.4 8.1 1.5e-11 44.0 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 RUS83621.1 - 0.0006 19.0 9.2 0.00074 18.7 9.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region STE3 PF02076.15 RUS83621.1 - 0.0021 17.3 5.1 0.003 16.8 5.1 1.3 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 RUS83621.1 - 0.0078 15.6 4.6 0.0093 15.3 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4184 PF13803.6 RUS83621.1 - 0.022 14.4 1.1 0.022 14.4 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4184) PepSY_TM PF03929.16 RUS83621.1 - 0.28 10.8 1.3 0.41 10.3 1.3 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF872 PF05915.12 RUS83621.1 - 0.66 10.2 2.6 1.3 9.2 0.6 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF1345 PF07077.11 RUS83621.1 - 0.72 9.5 5.2 2.7 7.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) FXa_inhibition PF14670.6 RUS83622.1 - 3.4e-08 33.6 8.8 3.4e-08 33.6 8.8 2.8 1 1 1 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 RUS83622.1 - 4.5e-08 33.2 10.2 4.5e-08 33.2 10.2 3.4 3 1 0 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.7 RUS83622.1 - 8e-08 32.1 13.9 6.2e-05 22.8 3.3 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like Dynamitin PF04912.14 RUS83622.1 - 0.00012 21.6 4.1 0.00012 21.6 4.1 2.5 2 1 0 2 2 2 1 Dynamitin EGF_3 PF12947.7 RUS83622.1 - 0.0014 18.8 6.0 0.0014 18.8 6.0 3.4 3 0 0 3 3 3 1 EGF domain BLOC1_2 PF10046.9 RUS83622.1 - 0.002 18.4 1.8 0.002 18.4 1.8 3.4 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EGF PF00008.27 RUS83622.1 - 0.0028 17.9 29.6 0.025 14.9 9.2 3.4 3 0 0 3 3 3 2 EGF-like domain ABC_tran_CTD PF16326.5 RUS83622.1 - 0.016 15.4 18.6 0.36 11.1 2.4 4.6 3 1 1 4 4 4 0 ABC transporter C-terminal domain Cauli_AT PF03233.13 RUS83622.1 - 0.019 14.9 5.3 2.1 8.3 0.1 2.9 2 1 1 3 3 3 0 Aphid transmission protein Prefoldin PF02996.17 RUS83622.1 - 0.072 13.0 12.3 1.3 9.0 0.5 4.4 3 1 1 4 4 4 0 Prefoldin subunit PhoU_div PF01865.16 RUS83622.1 - 0.39 10.0 4.5 1.1 8.5 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF47 hEGF PF12661.7 RUS83622.1 - 0.47 11.2 25.6 0.064 13.9 6.0 3.3 3 0 0 3 3 2 0 Human growth factor-like EGF DUF4164 PF13747.6 RUS83622.1 - 0.48 10.7 7.6 9.7 6.5 1.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4592 PF15262.6 RUS83622.1 - 0.57 10.9 3.8 7.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Baculo_PEP_C PF04513.12 RUS83622.1 - 1.6 8.8 10.5 2.2 8.3 2.5 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 RUS83622.1 - 2.4 9.0 6.9 6.5 7.5 1.1 3.6 3 1 1 4 4 4 0 Occludin homology domain NPV_P10 PF05531.12 RUS83622.1 - 3 8.4 10.6 13 6.4 3.5 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RUS83622.1 - 4 7.5 13.1 4.7 7.3 4.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 RUS83622.1 - 5.5 7.4 16.3 0.82 10.1 3.0 4.1 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC-167 PF15188.6 RUS83622.1 - 7.2 7.0 9.2 4.2 7.8 1.2 3.4 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Prominin PF05478.11 RUS83622.1 - 8.8 4.1 13.1 1.5 6.6 1.5 2.1 1 1 1 2 2 2 0 Prominin zf-C2H2 PF00096.26 RUS83623.1 - 5.6e-37 124.2 178.2 0.0018 18.6 0.8 24.7 25 0 0 25 25 25 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS83623.1 - 3.8e-26 89.5 178.2 0.0019 18.9 0.8 26.2 27 0 0 27 27 27 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS83623.1 - 3.7e-09 36.6 48.9 0.0011 19.2 0.2 13.0 14 0 0 14 14 14 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 RUS83623.1 - 9.4e-09 35.5 66.6 0.047 14.0 1.0 11.6 7 3 4 11 11 11 9 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 RUS83623.1 - 5.7e-08 32.8 11.1 4.8e-05 23.6 0.1 18.6 21 0 0 21 21 21 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS83623.1 - 0.00062 19.7 65.2 0.032 14.2 0.9 11.5 12 0 0 12 12 12 5 C2H2-type zinc finger zf-Di19 PF05605.12 RUS83623.1 - 0.003 17.8 2.0 0.003 17.8 2.0 12.2 15 2 1 16 16 16 2 Drought induced 19 protein (Di19), zinc-binding DUF5348 PF17295.2 RUS83623.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) zf-FPG_IleRS PF06827.14 RUS83623.1 - 0.3 11.0 9.2 28 4.7 0.2 5.9 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zf-ribbon_3 PF13248.6 RUS83623.1 - 0.63 9.5 24.3 1.3 8.5 0.0 7.3 7 0 0 7 7 7 0 zinc-ribbon domain DUF5323 PF17257.2 RUS83625.1 - 0.0058 16.5 29.2 2.6 8.0 1.5 5.0 1 1 4 5 5 5 5 Family of unknown function (DUF5323) Peptidase_C2 PF00648.21 RUS83626.1 - 4.5e-100 334.5 0.1 5.7e-100 334.2 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS83626.1 - 2.1e-34 118.8 0.0 3.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III PH PF00169.29 RUS83627.1 - 2.4e-05 24.8 0.0 4.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF4220 PF13968.6 RUS83627.1 - 0.0013 18.3 0.4 0.0014 18.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) Folliculin PF11704.8 RUS83627.1 - 0.0031 17.4 0.3 0.004 17.1 0.3 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PH_16 PF17838.1 RUS83627.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF5344 PF17279.2 RUS83628.1 - 0.0049 17.4 0.8 6.6 7.4 0.0 4.3 4 0 0 4 4 4 2 Family of unknown function (DUF5344) RVT_1 PF00078.27 RUS83629.1 - 2.6e-29 102.4 0.0 3.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 RUS83629.1 - 7.8e-05 22.2 9.6 0.0001 21.8 9.6 1.1 1 0 0 1 1 1 1 BUD22 Seipin PF06775.14 RUS83629.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) PPP4R2 PF09184.11 RUS83629.1 - 2.1 7.9 9.9 3.8 7.0 9.9 1.4 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 RUS83629.1 - 4.5 6.6 12.8 8.1 5.8 12.8 1.5 1 0 0 1 1 1 0 SDA1 GAGA_bind PF06217.12 RUS83630.1 - 0.00029 21.2 16.0 0.00033 21.0 16.0 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.14 RUS83630.1 - 0.00039 20.9 10.2 0.00047 20.6 10.2 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Vfa1 PF08432.10 RUS83630.1 - 0.00061 20.2 24.1 0.00072 19.9 24.1 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 RUS83630.1 - 0.0016 18.6 3.3 0.0019 18.4 3.3 1.2 1 0 0 1 1 1 1 DDHD domain SOBP PF15279.6 RUS83630.1 - 0.0019 18.9 6.1 0.0021 18.7 6.1 1.1 1 0 0 1 1 1 1 Sine oculis-binding protein DUF4776 PF16003.5 RUS83630.1 - 0.0047 16.0 20.4 0.0053 15.8 20.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) Eapp_C PF10238.9 RUS83630.1 - 0.0054 16.8 10.6 0.0091 16.1 10.6 1.4 1 0 0 1 1 1 1 E2F-associated phosphoprotein PPL5 PF18168.1 RUS83630.1 - 0.0063 15.9 16.0 0.0081 15.5 16.0 1.1 1 0 0 1 1 1 1 Prim-pol family 5 CPSF100_C PF13299.6 RUS83630.1 - 0.0063 16.7 11.1 0.0086 16.3 11.1 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DUF2126 PF09899.9 RUS83630.1 - 0.0092 14.1 5.9 0.011 13.8 5.9 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.16 RUS83630.1 - 0.016 15.2 3.1 0.018 15.1 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCM_bind PF09739.9 RUS83630.1 - 0.018 13.5 13.1 0.021 13.3 13.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF5308 PF17233.2 RUS83630.1 - 0.02 15.1 1.1 0.025 14.8 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Tim54 PF11711.8 RUS83630.1 - 0.023 13.5 14.8 0.029 13.1 14.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 RUS83630.1 - 0.032 13.8 55.4 0.047 13.3 27.5 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein EOS1 PF12326.8 RUS83630.1 - 0.033 14.1 5.5 0.043 13.7 5.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein TraV PF09676.10 RUS83630.1 - 0.033 15.2 12.0 0.045 14.7 12.0 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF913 PF06025.12 RUS83630.1 - 0.064 12.2 5.4 0.073 12.0 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3807 PF12720.7 RUS83630.1 - 0.065 13.5 23.7 0.089 13.1 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) LicD PF04991.13 RUS83630.1 - 0.076 13.1 14.8 0.1 12.8 14.8 1.1 1 0 0 1 1 1 0 LicD family Zip PF02535.22 RUS83630.1 - 0.077 12.2 7.4 0.094 11.9 7.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SRP-alpha_N PF04086.13 RUS83630.1 - 0.079 12.9 27.7 0.099 12.6 27.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SpoIIP PF07454.11 RUS83630.1 - 0.09 12.2 15.5 0.11 11.9 15.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 RUS83630.1 - 0.11 10.9 0.8 0.11 10.9 0.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NARP1 PF12569.8 RUS83630.1 - 0.12 11.3 29.8 0.14 11.0 29.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 RUS83630.1 - 0.16 11.7 18.2 0.21 11.3 18.2 1.1 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 RUS83630.1 - 0.16 10.9 13.7 0.2 10.6 13.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DAG_kinase_N PF14513.6 RUS83630.1 - 0.18 12.0 13.4 0.25 11.5 13.4 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF1943 PF09172.11 RUS83630.1 - 0.19 10.9 9.2 0.21 10.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4614 PF15391.6 RUS83630.1 - 0.19 11.7 8.6 0.26 11.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4551 PF15087.6 RUS83630.1 - 0.2 10.5 7.8 0.24 10.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4569 PF15133.6 RUS83630.1 - 0.22 11.2 8.5 0.24 11.1 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) MDFI PF15316.6 RUS83630.1 - 0.26 11.4 7.3 0.33 11.0 7.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor FGF-BP1 PF06473.12 RUS83630.1 - 0.29 10.9 24.1 0.38 10.6 24.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF1764 PF08576.10 RUS83630.1 - 0.37 11.7 28.4 0.62 11.0 28.4 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AAA_11 PF13086.6 RUS83630.1 - 0.49 10.1 17.5 0.66 9.7 17.5 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 RUS83630.1 - 0.68 8.6 13.4 0.87 8.3 13.4 1.1 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 RUS83630.1 - 0.74 9.2 9.9 1 8.7 9.9 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4228 PF14009.6 RUS83630.1 - 0.74 10.2 10.7 0.97 9.8 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF4407 PF14362.6 RUS83630.1 - 0.77 9.1 7.3 0.99 8.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 RUS83630.1 - 0.83 9.4 10.5 1.2 8.8 10.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RPOL_N PF14700.6 RUS83630.1 - 0.94 8.8 19.4 1.2 8.5 19.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Dsh_C PF12316.8 RUS83630.1 - 0.94 9.8 6.0 1.3 9.4 6.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MDM31_MDM32 PF08118.11 RUS83630.1 - 1 7.9 9.0 1.3 7.6 9.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF5427 PF10310.9 RUS83630.1 - 1.1 8.2 17.9 1.3 7.9 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ALMT PF11744.8 RUS83630.1 - 1.1 8.0 10.8 1.4 7.7 10.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2052 PF09747.9 RUS83630.1 - 1.3 9.2 14.3 1.6 8.8 14.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Cellulose_synt PF03552.14 RUS83630.1 - 1.7 7.0 10.3 2.3 6.6 10.3 1.2 1 0 0 1 1 1 0 Cellulose synthase Otopetrin PF03189.13 RUS83630.1 - 1.7 7.4 4.4 2.2 7.0 4.4 1.2 1 0 0 1 1 1 0 Otopetrin TMEM214 PF10151.9 RUS83630.1 - 1.7 7.0 28.5 2.4 6.5 28.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RPN2_C PF18004.1 RUS83630.1 - 2.1 8.3 34.8 2.8 7.8 34.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NPR3 PF03666.13 RUS83630.1 - 2.2 7.0 23.5 2.8 6.6 23.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 RUS83630.1 - 2.2 7.7 25.3 3.7 7.0 25.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4770 PF15994.5 RUS83630.1 - 2.5 8.3 19.0 4.8 7.4 19.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CENP-N PF05238.13 RUS83630.1 - 3.2 6.9 15.8 4.4 6.5 15.8 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like AF-4 PF05110.13 RUS83630.1 - 4.2 5.3 31.6 5.1 5.1 31.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Paramyxo_ncap PF00973.19 RUS83630.1 - 4.3 6.1 12.2 5.3 5.8 12.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein YL1 PF05764.13 RUS83630.1 - 4.6 7.3 35.2 5.8 7.0 35.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein V_ATPase_I PF01496.19 RUS83630.1 - 4.7 5.0 16.6 6 4.7 16.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDM10 PF12519.8 RUS83630.1 - 4.8 5.9 14.2 6 5.6 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FancD2 PF14631.6 RUS83630.1 - 5 4.4 19.2 6.2 4.1 19.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Band_3_cyto PF07565.13 RUS83630.1 - 5.2 6.8 10.7 7.3 6.3 10.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DNApol_Exo PF18136.1 RUS83630.1 - 6.3 5.8 12.5 10 5.1 12.5 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF3987 PF13148.6 RUS83630.1 - 8 5.4 13.9 10 5.0 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RR_TM4-6 PF06459.12 RUS83630.1 - 8.3 6.1 28.7 0.71 9.6 24.3 1.4 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 RUS83630.1 - 8.3 5.2 9.0 10 4.9 9.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RP-C_C PF11800.8 RUS83630.1 - 8.5 6.4 9.5 11 6.0 9.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Membralin PF09746.9 RUS83630.1 - 9.2 5.2 10.5 12 4.9 10.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3438 PF11920.8 RUS83630.1 - 9.2 5.4 6.9 13 4.9 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Peroxin-13_N PF04088.13 RUS83630.1 - 9.6 6.5 9.7 15 5.9 9.7 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DDRGK PF09756.9 RUS83630.1 - 9.9 5.7 34.9 13 5.3 34.9 1.1 1 0 0 1 1 1 0 DDRGK domain Ion_trans PF00520.31 RUS83631.1 - 4.8e-36 124.2 17.2 6.8e-36 123.7 17.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 RUS83631.1 - 1e-19 70.7 0.0 2.2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 RUS83631.1 - 1.5e-13 50.6 0.0 3.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RUS83631.1 - 5e-10 39.2 2.1 5e-10 39.2 2.1 2.3 3 0 0 3 3 3 1 Ion channel PAS PF00989.25 RUS83631.1 - 5.2e-08 32.9 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 RUS83631.1 - 0.00056 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RUS83631.1 - 0.0042 17.3 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 PAS fold Cupin_2 PF07883.11 RUS83631.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Ank_2 PF12796.7 RUS83633.1 - 7.7e-69 228.3 26.3 7.1e-16 58.6 0.2 7.7 2 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS83633.1 - 2.8e-55 184.0 21.2 1.7e-12 47.6 0.3 9.8 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 RUS83633.1 - 1.4e-50 167.6 29.6 1.2e-06 28.7 0.0 13.9 13 1 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 RUS83633.1 - 9.8e-49 162.8 23.7 4.5e-08 33.2 0.2 13.2 4 2 10 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS83633.1 - 7.7e-46 148.8 23.1 6e-05 23.1 0.2 14.6 15 0 0 15 15 15 10 Ankyrin repeat SOCS_box PF07525.16 RUS83633.1 - 1.2e-09 38.3 2.3 2.7e-09 37.2 2.3 1.6 1 0 0 1 1 1 1 SOCS box Yip1 PF04893.17 RUS83634.1 - 1.9e-09 37.5 16.6 1.9e-09 37.5 16.6 1.8 1 1 1 2 2 2 1 Yip1 domain DUF1282 PF06930.12 RUS83634.1 - 0.23 11.2 9.8 0.33 10.7 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF3397 PF11877.8 RUS83634.1 - 0.99 9.6 11.3 0.14 12.3 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) YhhN PF07947.14 RUS83635.1 - 4.9e-30 104.5 7.0 4.9e-30 104.5 7.0 2.2 2 0 0 2 2 2 2 YhhN family Wzy_C_2 PF11846.8 RUS83635.1 - 0.014 15.4 0.1 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal SPC25 PF06703.11 RUS83635.1 - 6 6.6 5.7 1.9 8.3 1.1 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) YhhN PF07947.14 RUS83636.1 - 8.7e-16 58.1 16.5 9.4e-16 57.9 15.5 1.5 1 1 1 2 2 2 1 YhhN family Sas10_Utp3 PF04000.15 RUS83640.1 - 1.1e-15 58.0 0.0 2.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HMMR_C PF15908.5 RUS83640.1 - 0.009 16.3 2.1 0.043 14.1 2.0 1.8 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Peptidase_C97 PF05903.14 RUS83641.1 - 6e-43 146.3 0.0 6.9e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 RUS83641.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Lamp PF01299.17 RUS83642.1 - 0.00036 20.4 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ArsP_1 PF03773.13 RUS83642.1 - 0.025 13.7 0.2 0.035 13.3 0.2 1.2 1 0 0 1 1 1 0 Predicted permease TMEM154 PF15102.6 RUS83642.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF2062 PF09835.9 RUS83642.1 - 0.05 13.5 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Orf78 PF06024.12 RUS83642.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TFIIB PF00382.19 RUS83643.1 - 1.5e-22 79.4 0.1 5.1e-15 55.3 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 RUS83643.1 - 8.2e-13 48.6 5.7 8.2e-13 48.6 5.7 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 RUS83643.1 - 1.4e-11 43.7 3.2 4.9e-11 42.0 3.2 2.1 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 RUS83643.1 - 0.0032 17.5 0.2 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain PRCC PF10253.9 RUS83644.1 - 2.9 8.6 16.2 1.5 9.5 4.4 2.3 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Adenylsucc_synt PF00709.21 RUS83645.1 - 0.0078 15.2 0.3 0.01 14.8 0.3 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_2 PF12796.7 RUS83646.1 - 1.4e-87 288.3 10.9 1.6e-14 54.2 0.2 7.5 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS83646.1 - 1.9e-73 242.0 6.7 8.5e-10 39.0 0.0 11.6 4 4 8 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 RUS83646.1 - 1.4e-68 224.6 26.0 2.4e-07 30.9 0.0 14.9 14 1 1 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 RUS83646.1 - 1.6e-66 219.4 20.8 3.2e-10 40.1 0.4 11.0 3 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS83646.1 - 9.8e-62 197.6 6.1 9.6e-05 22.5 0.1 14.1 14 0 0 14 14 14 13 Ankyrin repeat HEM4 PF02602.15 RUS83646.1 - 6.4e-05 22.4 1.2 3.8 6.8 0.0 4.7 3 1 2 5 5 5 2 Uroporphyrinogen-III synthase HemD 7tm_2 PF00002.24 RUS83650.1 - 1.7e-06 27.5 23.5 3.6e-06 26.4 23.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pox_A14 PF05767.12 RUS83650.1 - 5.5 7.2 7.7 0.55 10.4 1.0 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 NACHT PF05729.12 RUS83651.1 - 8e-12 45.4 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF4062 PF13271.6 RUS83651.1 - 3.2e-11 43.5 0.1 2.2e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 RUS83651.1 - 4.5e-09 36.9 0.0 1.3e-08 35.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain ATPase_2 PF01637.18 RUS83651.1 - 8.1e-08 32.5 0.4 4.4e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 RUS83651.1 - 1.2e-07 32.1 0.1 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 RUS83651.1 - 2.3e-06 27.1 0.0 0.00045 19.6 0.0 2.6 2 1 1 3 3 3 1 KAP family P-loop domain AAA_29 PF13555.6 RUS83651.1 - 0.0003 20.5 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RUS83651.1 - 0.00054 19.4 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 RUS83651.1 - 0.00058 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 RUS83651.1 - 0.00085 19.9 0.2 0.0022 18.5 0.1 1.8 2 0 0 2 2 1 1 ABC transporter T2SSE PF00437.20 RUS83651.1 - 0.0043 16.1 0.2 0.0082 15.2 0.2 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 RUS83651.1 - 0.015 14.7 0.9 0.019 14.3 0.1 1.7 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 RUS83651.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 RUS83651.1 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 RUS83651.1 - 0.025 13.5 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TniB PF05621.11 RUS83651.1 - 0.029 13.8 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Ras PF00071.22 RUS83651.1 - 0.034 13.8 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras family PRK PF00485.18 RUS83651.1 - 0.037 13.7 0.2 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 RUS83651.1 - 0.049 12.8 0.2 0.076 12.2 0.2 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Helicase_RecD PF05127.14 RUS83651.1 - 0.06 13.2 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 Helicase Sigma54_activ_2 PF14532.6 RUS83651.1 - 0.08 13.1 1.5 1.7 8.7 0.0 3.2 3 1 1 4 4 3 0 Sigma-54 interaction domain DUF815 PF05673.13 RUS83651.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 RUS83651.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 RUS83651.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3981 PF13139.6 RUS83651.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) MobB PF03205.14 RUS83651.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4337 PF14235.6 RUS83651.1 - 0.35 11.0 1.3 0.66 10.1 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF87 PF01935.17 RUS83651.1 - 0.53 10.3 2.5 14 5.7 0.2 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 RUS83651.1 - 0.75 10.3 4.9 0.85 10.1 0.2 2.7 3 0 0 3 3 3 0 AAA domain Proteasome PF00227.26 RUS83652.1 - 1.1e-61 207.6 0.2 1.5e-61 207.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS83652.1 - 4.1e-14 51.9 0.6 1e-13 50.7 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pyrid_oxidase_2 PF13883.6 RUS83652.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RRN3 PF05327.11 RUS83656.1 - 0.00017 20.3 13.2 0.00017 20.3 13.2 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DDE_3 PF13358.6 RUS83656.1 - 0.0037 17.0 0.0 0.0073 16.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease CDC45 PF02724.14 RUS83656.1 - 0.0086 14.4 14.5 0.01 14.2 14.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 RUS83656.1 - 0.036 12.5 14.7 0.043 12.3 14.7 1.1 1 0 0 1 1 1 0 Mpp10 protein eIF-3c_N PF05470.12 RUS83656.1 - 0.046 12.0 3.1 0.06 11.7 3.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.12 RUS83656.1 - 0.32 10.3 17.7 3 7.2 18.9 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 RUS83656.1 - 0.36 8.9 42.6 0.44 8.6 42.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS83656.1 - 2.5 6.2 28.3 3.1 5.9 28.3 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_S10 PF00450.22 RUS83657.1 - 1.4e-78 265.2 2.0 6e-78 263.1 2.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 RUS83657.1 - 0.11 13.1 0.3 1.1 9.8 0.3 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zip PF02535.22 RUS83659.1 - 3.8e-42 144.7 4.5 4.7e-42 144.4 4.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PL48 PF15903.5 RUS83661.1 - 1.3e-29 103.3 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 PTR2 PF00854.21 RUS83662.1 - 9e-84 281.6 15.8 2e-83 280.5 15.8 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 RUS83662.1 - 0.00025 20.1 29.3 0.00025 20.1 29.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG27 PF09451.10 RUS83662.1 - 0.025 14.4 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 27 Pkinase PF00069.25 RUS83665.1 - 5.7e-54 183.2 0.0 1.1e-53 182.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83665.1 - 4.4e-24 85.2 0.0 1e-23 83.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase cNMP_binding PF00027.29 RUS83665.1 - 2.8e-21 75.4 0.0 3.1e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 RUS83665.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FAM76 PF16046.5 RUS83665.1 - 0.0064 15.9 0.9 0.01 15.2 0.4 1.6 1 1 1 2 2 2 1 FAM76 protein APH PF01636.23 RUS83665.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF641 PF04859.12 RUS83665.1 - 0.047 14.0 1.0 0.097 13.0 1.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Seadorna_VP7 PF07387.11 RUS83665.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF722 PF05263.11 RUS83665.1 - 0.12 12.6 1.2 2.5 8.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF722) TMF_DNA_bd PF12329.8 RUS83665.1 - 0.13 12.3 3.3 0.13 12.2 1.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 RUS83665.1 - 0.2 11.8 3.4 0.35 10.9 3.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MPS2 PF17060.5 RUS83665.1 - 0.85 8.8 5.3 36 3.5 3.6 2.5 2 1 0 2 2 2 0 Monopolar spindle protein 2 DEAD PF00270.29 RUS83666.1 - 6.6e-49 166.1 0.0 5.4e-48 163.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS83666.1 - 5.1e-29 100.8 0.0 3.6e-28 98.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS83666.1 - 2.6e-05 24.3 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RUS83666.1 - 0.028 13.6 0.1 0.028 13.6 0.1 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase ABC_membrane PF00664.23 RUS83667.1 - 2.3e-59 201.3 22.1 7.7e-36 124.2 3.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS83667.1 - 3.9e-51 173.2 0.0 8e-30 104.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 RUS83667.1 - 3.8e-07 30.7 0.6 0.0074 16.7 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RUS83667.1 - 4.4e-06 26.3 3.4 0.34 10.3 0.1 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS83667.1 - 1.6e-05 25.0 0.4 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS83667.1 - 5.1e-05 23.3 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS83667.1 - 0.00095 19.4 0.1 5.5 7.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 RUS83667.1 - 0.0039 17.3 0.6 0.028 14.5 0.1 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 RUS83667.1 - 0.0045 16.7 0.2 4.7 7.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 RUS83667.1 - 0.0099 15.5 0.1 3.4 7.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 RUS83667.1 - 0.03 14.4 3.6 0.69 10.0 0.2 2.3 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 RUS83667.1 - 0.031 13.4 0.2 7.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RUS83667.1 - 0.072 12.6 0.0 7 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 RUS83667.1 - 0.14 11.2 0.1 14 4.6 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.6 RUS83667.1 - 0.15 11.8 0.0 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PriC PF07445.12 RUS83668.1 - 0.027 14.4 3.3 0.061 13.2 3.2 1.6 1 1 0 1 1 1 0 Primosomal replication protein priC PUL PF08324.11 RUS83668.1 - 1.8 7.7 8.1 0.39 9.9 0.2 2.9 3 1 1 4 4 4 0 PUL domain LapA_dom PF06305.11 RUS83669.1 - 0.29 11.0 11.0 1.6 8.6 0.1 2.8 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain HemY_N PF07219.13 RUS83669.1 - 4.7 7.4 7.6 0.43 10.8 1.2 2.3 3 0 0 3 3 3 0 HemY protein N-terminus YiaAB PF05360.14 RUS83669.1 - 7.4 6.9 15.9 23 5.4 1.7 3.8 3 1 1 4 4 4 0 yiaA/B two helix domain IDO PF01231.18 RUS83670.1 - 3.1e-31 108.6 0.0 3.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.18 RUS83671.1 - 9.7e-61 205.9 0.2 9e-60 202.7 0.2 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 RUS83671.1 - 0.0092 14.8 0.0 0.27 10.0 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1864) ZapD PF07072.11 RUS83671.1 - 0.012 15.4 0.3 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Cell division protein DUF1340 PF07067.11 RUS83671.1 - 0.023 14.1 0.1 0.57 9.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1340) IL2 PF00715.17 RUS83671.1 - 0.12 12.4 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 Interleukin 2 Nup88 PF10168.9 RUS83671.1 - 0.12 10.2 1.4 0.18 9.6 1.4 1.1 1 0 0 1 1 1 0 Nuclear pore component SKG6 PF08693.10 RUS83672.1 - 1.1e-05 24.7 2.0 1.9e-05 24.0 2.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 RUS83672.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein melan-A TMEM154 PF15102.6 RUS83672.1 - 0.012 15.5 0.0 0.012 15.5 0.0 3.5 1 1 1 2 2 2 0 TMEM154 protein family 7tm_1 PF00001.21 RUS83676.1 - 2.7e-35 122.0 22.8 4.1e-35 121.4 22.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS83676.1 - 6.8e-08 32.5 24.8 1e-07 31.9 24.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS83676.1 - 0.0019 18.0 12.1 0.004 16.9 12.1 1.7 1 1 0 1 1 1 1 Olfactory receptor Abhydrolase_9_N PF15420.6 RUS83676.1 - 1.4 8.9 9.7 0.029 14.4 1.4 2.2 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus KH_1 PF00013.29 RUS83679.1 - 3.2e-152 494.6 39.3 2.2e-16 59.4 1.4 12.1 12 0 0 12 12 12 12 KH domain SLS PF14611.6 RUS83679.1 - 1.2e-17 64.5 11.2 4.5e-05 23.4 0.2 7.9 1 1 7 8 8 8 7 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 RUS83679.1 - 3.3e-16 58.9 29.3 0.0082 15.9 2.0 10.0 9 2 1 10 10 10 6 KH domain KH_5 PF13184.6 RUS83679.1 - 9.7e-05 22.4 20.5 0.93 9.6 0.1 8.2 8 1 0 8 8 8 2 NusA-like KH domain YbbR PF07949.12 RUS83679.1 - 0.00015 22.0 22.7 2.1 8.7 0.1 9.8 10 1 0 10 10 10 1 YbbR-like protein DUF2096 PF09869.9 RUS83679.1 - 0.0028 17.8 15.1 3 7.9 0.0 7.8 7 2 1 9 9 9 1 Uncharacterized protein conserved in archaea (DUF2096) AAA PF00004.29 RUS83680.1 - 5.7e-41 140.0 0.0 1.9e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS83680.1 - 1.3e-08 34.5 0.1 3.2e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RUS83680.1 - 9.7e-05 22.7 0.0 0.004 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RUS83680.1 - 0.00015 21.8 0.1 0.00073 19.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RUS83680.1 - 0.00094 19.3 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RUS83680.1 - 0.0011 18.2 0.0 0.0031 16.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 RUS83680.1 - 0.0015 18.9 0.2 0.029 14.7 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 RUS83680.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RUS83680.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS83680.1 - 0.015 14.8 0.0 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RUS83680.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS83680.1 - 0.017 15.7 0.0 0.054 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 RUS83680.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 RUS83680.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 RUS83680.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 RUS83680.1 - 0.092 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 RUS83680.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 RUS83680.1 - 0.12 12.1 0.3 0.81 9.4 0.0 2.4 3 1 0 3 3 3 0 AAA domain AAA_3 PF07726.11 RUS83680.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS83680.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Integrase_H2C2 PF17921.1 RUS83681.1 - 2.6e-09 37.0 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS83681.1 - 4.9e-05 23.5 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain 7tm_1 PF00001.21 RUS83683.1 - 4.5e-08 32.7 13.0 4.5e-08 32.7 13.0 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS83683.1 - 9.8e-05 21.8 13.8 0.0017 17.7 2.5 2.3 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw Baculo_PEP_C PF04513.12 RUS83684.1 - 0.0042 17.1 3.6 0.0056 16.7 1.7 2.1 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 RUS83684.1 - 0.0098 15.7 0.8 0.016 15.0 0.8 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain CLZ PF16526.5 RUS83684.1 - 0.019 15.3 0.5 6.2 7.3 0.1 2.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 RUS83684.1 - 0.025 14.9 0.3 0.064 13.5 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1640 PF07798.11 RUS83684.1 - 0.059 13.4 0.2 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Med9 PF07544.13 RUS83684.1 - 0.061 13.4 0.1 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.18 RUS83684.1 - 0.074 12.4 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4607 PF15380.6 RUS83684.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DUF2536 PF10750.9 RUS83684.1 - 0.18 11.8 0.9 1.7 8.6 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2536) SlyX PF04102.12 RUS83684.1 - 0.3 11.7 1.2 23 5.7 0.1 2.7 2 1 1 3 3 3 0 SlyX XhlA PF10779.9 RUS83684.1 - 0.44 10.8 4.4 0.63 10.3 1.7 2.5 2 1 1 3 3 3 0 Haemolysin XhlA Ecl1 PF12855.7 RUS83686.1 - 0.059 14.5 1.0 0.13 13.5 1.0 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MACPF PF01823.19 RUS83686.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.0 3 0 0 3 3 3 0 MAC/Perforin domain CLZ PF16526.5 RUS83686.1 - 0.3 11.5 1.0 26 5.3 0.1 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels STI1 PF17830.1 RUS83689.1 - 4.6e-07 29.7 3.6 96 3.0 0.0 8.1 9 0 0 9 9 9 0 STI1 domain Viral_cys_rich PF08008.12 RUS83689.1 - 5.2e-05 23.2 2.1 27 4.9 0.0 4.9 1 1 8 9 9 9 3 Viral cysteine rich HGAL PF15666.5 RUS83689.1 - 0.00043 20.3 4.2 28 4.9 0.0 4.8 1 1 4 5 5 5 1 Germinal center-associated lymphoma Antimicrobial25 PF16839.5 RUS83689.1 - 0.53 10.4 13.8 0.81 9.8 0.9 4.3 2 2 4 6 6 6 0 Nematode antimicrobial peptide DUF2644 PF10841.8 RUS83689.1 - 0.65 10.3 21.9 1e+02 3.2 0.1 7.9 9 0 0 9 9 9 0 Protein of unknown function (DUF2644) Con-6 PF10346.9 RUS83689.1 - 4.5 7.4 4.9 1.8e+02 2.2 0.1 3.9 3 0 0 3 3 3 0 Conidiation protein 6 BACK PF07707.15 RUS83690.1 - 1.5e-07 31.4 0.0 1.5e-07 31.4 0.0 2.7 3 1 0 3 3 3 1 BTB And C-terminal Kelch Transposase_1 PF01359.18 RUS83691.1 - 4.2e-16 58.5 0.1 4.2e-16 58.5 0.1 1.9 3 0 0 3 3 3 1 Transposase (partial DDE domain) tRNA-synt_1b PF00579.25 RUS83692.1 - 2.7e-72 243.5 0.0 3.6e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 RUS83692.1 - 0.0044 16.7 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain Vac_ImportDeg PF09783.9 RUS83693.1 - 7.5e-62 207.9 2.4 8.7e-62 207.7 2.4 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein ATP12 PF07542.11 RUS83694.1 - 7.1e-33 113.4 0.4 3.2e-32 111.3 0.2 1.9 2 0 0 2 2 2 1 ATP12 chaperone protein OrfA PF17495.2 RUS83694.1 - 0.0091 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Vpr-like OrfA Cofilin_ADF PF00241.20 RUS83694.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein mRNA_decap_C PF16741.5 RUS83694.1 - 0.12 11.7 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus LRR_9 PF14580.6 RUS83695.1 - 4.2e-17 62.2 9.5 1.2e-16 60.7 3.7 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 RUS83695.1 - 5.7e-12 45.7 20.5 1e-05 25.8 5.3 4.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS83695.1 - 4.1e-06 26.5 18.5 0.00062 19.5 5.6 3.8 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 RUS83695.1 - 0.34 11.6 5.6 28 5.8 0.0 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat CDPS PF16715.5 RUS83695.1 - 0.47 10.1 3.2 0.9 9.1 2.8 1.8 1 1 0 1 1 1 0 Cyclodipeptide synthase HPIP PF15226.6 RUS83696.1 - 0.059 13.8 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Gpi1 PF05024.15 RUS83697.1 - 3.9e-59 199.9 11.0 3.9e-59 199.9 11.0 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Peptidase_C26 PF07722.13 RUS83698.1 - 0.00022 21.0 0.0 0.00058 19.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 RUS83698.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Ras PF00071.22 RUS83699.1 - 7.9e-50 168.6 0.0 1.4e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 Ras family BTB PF00651.31 RUS83699.1 - 4.7e-30 104.1 2.6 2.6e-16 59.8 0.6 3.4 2 1 0 2 2 2 2 BTB/POZ domain Roc PF08477.13 RUS83699.1 - 3.2e-20 72.6 0.0 7.9e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS83699.1 - 1.6e-05 24.4 0.0 4.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Phage_DsbA PF11126.8 RUS83699.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DsbA MMR_HSR1 PF01926.23 RUS83699.1 - 0.17 12.0 0.0 0.93 9.6 0.0 2.2 2 1 0 3 3 3 0 50S ribosome-binding GTPase Dynein_light PF01221.18 RUS83700.1 - 7.3e-28 96.7 0.5 8.9e-28 96.4 0.5 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 RUS83700.1 - 0.0032 17.3 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) LRR_4 PF12799.7 RUS83701.1 - 1.6e-06 28.3 16.0 0.02 15.3 0.3 5.1 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS83701.1 - 7.3e-05 22.4 23.7 0.25 11.1 7.8 6.0 4 2 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 RUS83701.1 - 0.00034 20.7 12.6 19 6.3 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS83701.1 - 0.00044 20.1 17.5 1.3 9.3 0.6 7.0 8 0 0 8 8 8 3 Leucine Rich repeat Ribosomal_S7 PF00177.21 RUS83702.1 - 1.1e-35 122.5 0.8 1.5e-35 122.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF4747 PF15931.5 RUS83702.1 - 0.013 15.1 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) CaMBD PF02888.16 RUS83702.1 - 0.33 11.1 3.2 0.25 11.5 0.5 2.1 2 0 0 2 2 2 0 Calmodulin binding domain THP2 PF09432.10 RUS83703.1 - 0.055 13.5 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 GAD PF02938.14 RUS83703.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 GAD domain Aminotran_3 PF00202.21 RUS83704.1 - 1.4e-80 271.0 0.0 1.8e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MNHE PF01899.16 RUS83704.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit AAA PF00004.29 RUS83705.1 - 1e-39 136.0 0.0 1.9e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS83705.1 - 6.3e-14 51.5 2.3 6.9e-12 45.0 0.0 3.4 4 0 0 4 4 4 1 AAA+ lid domain Vps4_C PF09336.10 RUS83705.1 - 2.8e-10 40.0 0.6 8.9e-10 38.4 0.2 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RUS83705.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RUS83705.1 - 1.7e-05 25.3 0.0 0.003 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RUS83705.1 - 3.9e-05 23.4 0.0 7.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RUS83705.1 - 0.00021 21.5 0.2 0.00061 20.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 RUS83705.1 - 0.00026 21.0 0.1 0.0022 18.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RUS83705.1 - 0.00046 19.5 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 RUS83705.1 - 0.0016 17.8 0.1 0.0083 15.5 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RUS83705.1 - 0.0049 16.6 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 RUS83705.1 - 0.012 15.9 0.3 0.12 12.8 0.0 2.8 3 1 0 3 3 2 0 RNA helicase AAA_14 PF13173.6 RUS83705.1 - 0.013 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS83705.1 - 0.014 14.9 0.2 0.047 13.2 0.2 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region MHCassoc_trimer PF08831.10 RUS83705.1 - 0.026 14.5 2.9 0.026 14.5 0.4 2.2 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain PhoH PF02562.16 RUS83705.1 - 0.036 13.5 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 RUS83705.1 - 0.063 13.8 0.8 0.24 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_L12 PF00542.19 RUS83705.1 - 0.087 13.2 0.5 1.3 9.5 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain ATPase PF06745.13 RUS83705.1 - 0.089 12.1 0.1 1.5 8.2 0.1 2.2 1 1 0 2 2 2 0 KaiC AAA_22 PF13401.6 RUS83705.1 - 0.1 12.9 3.1 0.15 12.4 0.2 2.6 3 1 1 4 4 3 0 AAA domain AAA_28 PF13521.6 RUS83705.1 - 0.12 12.7 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS83705.1 - 0.13 11.9 0.2 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RUS83705.1 - 0.14 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RUS83705.1 - 0.58 10.6 0.1 0.58 10.6 0.1 2.2 3 0 0 3 3 1 0 AAA domain DUF4464 PF14713.6 RUS83706.1 - 1.4e-97 325.6 0.6 1.6e-97 325.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) HLH PF00010.26 RUS83707.1 - 1.9e-15 56.6 0.2 3.8e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spore_YpjB PF09577.10 RUS83707.1 - 0.074 12.8 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Terminase_4 PF05119.12 RUS83707.1 - 0.2 12.1 2.7 0.4 11.1 0.5 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit Ocnus PF05005.15 RUS83710.1 - 4.5e-40 136.1 0.1 5.1e-40 135.9 0.1 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) HCMVantigenic_N PF12154.8 RUS83711.1 - 0.0032 17.6 12.8 61 3.9 0.1 7.0 1 1 10 11 11 11 0 Glycoprotein B N-terminal antigenic domain of HCMV Epiglycanin_TR PF05647.11 RUS83711.1 - 0.0032 17.3 0.2 19 5.3 0.0 4.0 2 1 6 8 8 8 3 Tandem-repeating region of mucin, epiglycanin-like Integrase_Zn PF02022.19 RUS83711.1 - 2.2 8.3 19.1 69 3.5 0.2 7.3 3 2 4 8 8 8 0 Integrase Zinc binding domain SAM_1 PF00536.30 RUS83712.1 - 1.5e-33 115.0 0.2 4.3e-18 65.5 0.3 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS83712.1 - 2e-24 85.4 0.0 3.2e-11 43.2 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) RGCC PF15151.6 RUS83712.1 - 0.021 15.1 0.3 0.092 13.0 0.3 2.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family Ank_4 PF13637.6 RUS83713.1 - 2.7e-41 139.4 16.1 7.1e-10 39.2 0.1 5.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS83713.1 - 4.8e-34 116.8 6.3 6e-14 52.4 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS83713.1 - 1.3e-30 105.0 8.5 1.4e-08 34.8 0.1 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS83713.1 - 9.5e-29 96.3 6.2 1.6e-06 28.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 RUS83713.1 - 1.1e-26 92.0 14.7 1.5e-07 31.6 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat SH3_2 PF07653.17 RUS83713.1 - 1.1e-10 41.1 0.0 1.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS83713.1 - 5.3e-05 22.7 0.0 9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS83713.1 - 6.9e-05 22.6 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shisa PF13908.6 RUS83714.1 - 0.14 12.3 1.3 0.22 11.8 1.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3377 PF11857.8 RUS83714.1 - 0.26 11.2 8.0 0.61 10.1 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2207 PF09972.9 RUS83714.1 - 1.4 7.6 6.4 1.9 7.1 6.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 RUS83714.1 - 1.5 8.4 10.1 2.7 7.6 10.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family MMPL PF03176.15 RUS83714.1 - 5.1 5.9 9.1 6.9 5.5 9.1 1.1 1 0 0 1 1 1 0 MMPL family DUF3043 PF11241.8 RUS83714.1 - 5.5 7.0 5.4 8.6 6.4 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) NDK PF00334.19 RUS83718.1 - 4.1e-43 146.6 0.0 5.1e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 RUS83718.1 - 7.6e-18 63.9 0.4 1.2e-17 63.3 0.4 1.3 1 0 0 1 1 1 1 Dpy-30 motif IRF PF00605.17 RUS83719.1 - 1.2e-18 67.3 0.2 2.9e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 RUS83719.1 - 8.9e-14 51.7 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Interferon-regulatory factor 3 CD20 PF04103.15 RUS83720.1 - 0.0007 19.7 15.7 0.0007 19.7 15.7 3.3 4 0 0 4 4 4 2 CD20-like family MCR PF18509.1 RUS83720.1 - 0.049 13.2 4.3 3.2 7.4 0.2 2.9 2 0 0 2 2 2 0 Magnetochrome domain Tmem26 PF09772.9 RUS83721.1 - 0.0049 16.3 1.1 0.0049 16.3 1.1 1.4 2 0 0 2 2 2 1 Transmembrane protein 26 UBA_4 PF14555.6 RUS83722.1 - 1.2e-10 41.0 0.2 1.7e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 RUS83722.1 - 0.00076 19.1 0.5 0.0015 18.1 0.5 1.5 1 0 0 1 1 1 1 TAP C-terminal domain ThiF PF00899.21 RUS83722.1 - 0.049 13.0 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 ThiF family MAM PF00629.23 RUS83723.1 - 8.4e-18 64.8 0.1 1.5e-12 47.8 0.0 2.0 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 RUS83724.1 - 1.5e-45 155.0 1.2 9.4e-41 139.4 0.0 3.0 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu Peptidase_C13 PF01650.18 RUS83725.1 - 1.9e-49 168.5 0.0 2.3e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CPSase_L_D3 PF02787.19 RUS83725.1 - 0.13 12.7 0.0 9 6.7 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ADK PF00406.22 RUS83726.1 - 4.5e-111 367.7 2.8 1e-49 168.5 0.0 5.2 4 1 1 5 5 5 5 Adenylate kinase AAA_17 PF13207.6 RUS83726.1 - 5.1e-84 279.5 5.8 3.8e-33 114.8 0.0 5.4 4 1 1 5 5 5 4 AAA domain AAA_18 PF13238.6 RUS83726.1 - 3.7e-22 79.3 0.4 0.00035 21.1 0.0 5.8 4 2 1 5 5 5 4 AAA domain AAA_33 PF13671.6 RUS83726.1 - 3.5e-18 66.1 1.0 6.1e-05 23.2 0.0 5.9 4 2 0 5 5 5 3 AAA domain AAA_19 PF13245.6 RUS83726.1 - 1.2e-08 35.4 5.2 0.46 10.8 0.1 5.0 5 1 0 5 5 5 3 AAA domain Zeta_toxin PF06414.12 RUS83726.1 - 1.1e-07 31.4 2.3 0.24 10.7 0.0 4.4 4 0 0 4 4 4 2 Zeta toxin AAA_28 PF13521.6 RUS83726.1 - 1.3e-06 28.7 2.9 1.2 9.4 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 RUS83726.1 - 1.4e-06 28.8 1.0 7.9 6.9 0.1 4.8 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 RUS83726.1 - 7.1e-06 26.1 2.5 0.91 9.4 0.0 4.5 5 0 0 5 5 5 1 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 RUS83726.1 - 1.2e-05 25.2 0.5 0.74 9.5 0.0 4.0 4 0 0 4 4 4 2 Cytidylate kinase AAA_22 PF13401.6 RUS83726.1 - 8e-05 22.9 3.4 6.9 6.9 0.0 4.6 4 0 0 4 4 4 0 AAA domain Hydin_ADK PF17213.3 RUS83726.1 - 0.00013 22.4 0.0 12 6.1 0.0 4.3 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 RUS83726.1 - 0.00044 20.0 10.2 22 4.7 0.1 6.8 6 2 1 7 7 7 0 Thymidylate kinase ABC_tran PF00005.27 RUS83726.1 - 0.00055 20.5 2.9 3.6 8.1 0.0 4.0 4 0 0 4 4 3 1 ABC transporter NTPase_1 PF03266.15 RUS83726.1 - 0.0084 16.0 5.4 7.2 6.5 0.1 4.1 5 0 0 5 5 4 0 NTPase AAA_30 PF13604.6 RUS83726.1 - 0.025 14.3 4.0 27 4.4 0.1 4.2 4 0 0 4 4 4 0 AAA domain DUF5586 PF17824.1 RUS83726.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) RNA_helicase PF00910.22 RUS83726.1 - 0.11 12.8 3.3 38 4.7 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 RUS83726.1 - 0.14 11.8 4.3 19 4.9 0.1 4.2 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 RUS83726.1 - 0.19 10.9 5.0 19 4.3 0.1 3.7 4 0 0 4 4 4 0 NB-ARC domain Viral_helicase1 PF01443.18 RUS83726.1 - 0.25 11.0 4.7 39 3.9 0.1 3.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 RUS83726.1 - 0.32 10.8 5.9 40 4.1 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain DUF2075 PF09848.9 RUS83726.1 - 0.53 9.5 7.1 21 4.2 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 RUS83726.1 - 0.65 9.3 2.3 39 3.5 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 RUS83726.1 - 0.73 9.2 3.3 51 3.2 0.0 3.6 4 0 0 4 4 4 0 Chromatin associated protein KTI12 CobU PF02283.16 RUS83726.1 - 0.91 9.1 2.3 88 2.6 0.1 4.2 5 0 0 5 5 5 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SRP54 PF00448.22 RUS83726.1 - 1 8.9 5.2 14 5.3 0.0 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ATPase PF06745.13 RUS83726.1 - 2.4 7.4 7.4 8.3 5.7 0.1 4.0 4 0 0 4 4 4 0 KaiC NACHT PF05729.12 RUS83726.1 - 5.5 6.9 8.6 52 3.7 0.0 4.6 5 0 0 5 5 5 0 NACHT domain DUF4266 PF14086.6 RUS83727.1 - 2.9e-05 24.9 14.4 6.2 7.9 0.3 5.1 1 1 6 7 7 7 6 Domain of unknown function (DUF4266) DUF4337 PF14235.6 RUS83727.1 - 0.00082 19.5 4.4 0.17 12.0 4.4 3.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4337) HTH_19 PF12844.7 RUS83727.1 - 0.51 10.4 10.6 28 4.8 0.6 4.0 1 1 3 4 4 4 0 Helix-turn-helix domain DUF5415 PF17436.2 RUS83727.1 - 2.9 8.0 32.4 53 4.0 0.1 8.4 1 1 8 9 9 9 0 Family of unknown function (DUF5415) Ndc80_HEC PF03801.13 RUS83727.1 - 5.6 6.6 11.3 9.1 5.9 0.5 2.9 1 1 1 3 3 3 0 HEC/Ndc80p family ADK PF00406.22 RUS83728.1 - 2.1e-72 242.1 0.0 2.9e-49 167.0 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RUS83728.1 - 2.7e-45 154.1 0.0 4.1e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RUS83728.1 - 1.5e-09 38.2 0.0 6.3e-06 26.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RUS83728.1 - 6.5e-08 33.2 0.0 1.2e-05 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS83728.1 - 0.017 15.5 0.7 0.072 13.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RUS83728.1 - 0.052 13.5 0.1 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Longin PF13774.6 RUS83729.1 - 3.9e-27 94.1 0.2 6.4e-27 93.4 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RUS83729.1 - 5e-18 64.7 1.0 5e-18 64.7 1.0 1.8 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 RUS83729.1 - 0.038 13.9 0.5 0.038 13.9 0.5 2.0 2 0 0 2 2 2 0 Sec20 MULE PF10551.9 RUS83730.1 - 9e-21 74.1 0.2 2.2e-20 72.9 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain PHD PF00628.29 RUS83730.1 - 4.7e-08 32.8 9.7 1e-07 31.7 9.7 1.6 1 0 0 1 1 1 1 PHD-finger LRR_5 PF13306.6 RUS83730.1 - 4e-05 23.6 0.3 0.00011 22.1 0.3 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) PHD_2 PF13831.6 RUS83730.1 - 0.0035 16.9 3.6 0.0035 16.9 3.6 2.1 2 0 0 2 2 2 1 PHD-finger DUF5575 PF17738.1 RUS83730.1 - 0.026 13.6 0.4 4.7 6.2 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5575) zf-PHD-like PF15446.6 RUS83730.1 - 0.035 13.7 1.9 0.066 12.8 1.9 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Transposase_mut PF00872.18 RUS83730.1 - 0.035 13.0 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Transposase, Mutator family C1_2 PF03107.16 RUS83730.1 - 0.086 13.2 2.0 0.3 11.4 2.0 2.0 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 RUS83730.1 - 0.81 9.9 4.0 2.9 8.2 4.0 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Hyd_WA PF06462.12 RUS83730.1 - 1.1 9.4 2.7 2e+02 2.1 0.0 4.0 5 0 0 5 5 5 0 Propeller DUF3395 PF11875.8 RUS83731.1 - 3.2e-47 160.3 1.0 3.2e-47 160.3 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 RUS83731.1 - 2.8e-16 59.4 3.6 2.8e-16 59.4 3.6 2.1 3 0 0 3 3 3 1 DnaJ domain Peptidase_M13_N PF05649.13 RUS83731.1 - 0.029 14.1 1.2 3.9 7.1 0.4 2.3 2 0 0 2 2 2 0 Peptidase family M13 AFP PF02420.15 RUS83737.1 - 3.7e-07 29.7 3.2 2.3e+02 2.7 0.0 7.8 8 0 0 8 8 8 0 Insect antifreeze protein repeat RNase_II_C_S1 PF18614.1 RUS83737.1 - 0.0066 16.4 1.4 25 4.9 0.1 4.3 1 1 3 4 4 4 2 RNase II-type exonuclease C-terminal S1 domain DUF5631 PF18645.1 RUS83737.1 - 0.015 15.6 1.4 2.9 8.3 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5631) ATXN-1_C PF12547.8 RUS83737.1 - 0.71 10.2 10.1 9.5 6.6 0.4 4.2 1 1 5 6 6 6 0 Capicua transcriptional repressor modulator PilA4 PF18682.1 RUS83737.1 - 5.3 7.5 5.4 25 5.3 0.1 3.2 1 1 3 4 4 4 0 Pilin A4 Pkinase PF00069.25 RUS83738.1 - 2.8e-17 63.0 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83738.1 - 7.9e-11 41.7 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX PF00293.28 RUS83739.1 - 6.5e-13 48.9 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Peptidase_M13_N PF05649.13 RUS83741.1 - 5.2e-115 385.2 0.0 6.8e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS83741.1 - 7.4e-58 195.5 1.7 1.2e-57 194.9 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M13 Enolase_C PF00113.22 RUS83742.1 - 9.7e-157 520.7 0.1 1.4e-156 520.3 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RUS83742.1 - 5.1e-57 191.7 0.2 1.2e-56 190.5 0.2 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 RUS83742.1 - 2.8e-10 40.1 0.0 4.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RUS83742.1 - 0.00013 21.2 0.2 0.00031 20.0 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus GYF PF02213.16 RUS83743.1 - 2.1e-20 72.1 0.9 5e-20 70.9 0.9 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RUS83743.1 - 0.0002 21.1 0.1 0.00068 19.4 0.1 2.0 1 0 0 1 1 1 1 GYF domain 2 DUF3464 PF11947.8 RUS83745.1 - 0.0044 16.8 1.0 0.0044 16.8 1.0 2.2 3 0 0 3 3 3 1 Photosynthesis affected mutant 68 Me-amine-dh_L PF02975.14 RUS83745.1 - 0.19 12.2 0.0 0.83 10.2 0.0 1.8 1 1 1 2 2 2 0 Methylamine dehydrogenase, L chain DUF1075 PF06388.11 RUS83745.1 - 0.28 11.2 3.6 0.12 12.4 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) DUF4683 PF15735.5 RUS83746.1 - 0.022 14.4 0.2 0.022 14.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4683) WD40 PF00400.32 RUS83747.1 - 0.0045 17.8 0.0 0.0099 16.7 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.32 RUS83748.1 - 1.2e-13 51.3 25.3 0.00048 20.9 0.4 11.8 14 0 0 14 14 14 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83748.1 - 4.1e-11 43.0 0.0 0.019 15.2 0.0 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS83748.1 - 0.0029 17.0 2.7 3.3 7.0 0.0 3.8 3 1 0 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 RUS83748.1 - 0.014 15.8 0.1 0.43 11.1 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain Guanylate_cyc PF00211.20 RUS83749.1 - 1.3e-53 181.4 1.0 3.6e-28 98.4 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS83749.1 - 8.1e-07 28.7 0.2 1.3e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated Aldo_ket_red PF00248.21 RUS83750.1 - 4.9e-65 219.6 0.1 6.2e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kinesin PF00225.23 RUS83751.1 - 5.1e-115 383.9 0.0 8.3e-115 383.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 RUS83751.1 - 1e-56 192.0 2.7 1.5e-47 162.1 0.3 3.6 4 0 0 4 4 4 2 Kinesin-associated DUF3694 PF12473.8 RUS83751.1 - 3.1e-42 144.8 0.9 4.3e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 RUS83751.1 - 1.6e-22 80.0 0.0 7.6e-22 77.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 RUS83751.1 - 7.1e-12 45.6 0.2 7.1e-12 45.6 0.2 2.7 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 RUS83751.1 - 5.5e-10 39.7 0.1 1.1e-08 35.5 0.0 2.8 2 0 0 2 2 2 1 PH domain FHA PF00498.26 RUS83751.1 - 0.00017 21.9 0.0 0.00094 19.5 0.0 2.3 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 RUS83751.1 - 0.0065 16.9 1.6 0.01 16.3 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 RUS83751.1 - 0.014 15.7 0.1 0.036 14.3 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 RUS83751.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF4507 PF14964.6 RUS83752.1 - 0.00033 19.7 10.0 2.2 7.1 0.1 5.6 1 1 4 6 6 6 5 Domain of unknown function (DUF4507) DBINO PF13892.6 RUS83752.1 - 0.0028 18.0 13.9 2.5 8.5 0.1 6.9 3 2 5 9 9 9 3 DNA-binding domain FMO-like PF00743.19 RUS83753.1 - 3.1e-86 289.9 0.0 3.5e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS83753.1 - 1.7e-11 43.9 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS83753.1 - 1.3e-05 24.6 0.0 0.00097 18.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 RUS83753.1 - 0.0002 20.7 0.0 0.00071 18.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lectin_C PF00059.21 RUS83755.1 - 1.6e-20 73.8 0.7 8.2e-17 61.9 0.3 2.6 2 1 1 3 3 3 2 Lectin C-type domain GMC_oxred_C PF05199.13 RUS83756.1 - 2.8e-39 134.9 0.0 4.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 RUS83756.1 - 3.1e-25 89.2 0.5 5.2e-25 88.4 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lambda_CIII PF02061.16 RUS83758.1 - 0.032 14.3 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Lambda Phage CIII DUF4311 PF14188.6 RUS83758.1 - 0.042 13.6 0.2 0.056 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) TrbC PF04956.13 RUS83758.1 - 0.091 13.0 1.4 0.86 9.9 0.8 2.6 2 1 0 2 2 2 0 TrbC/VIRB2 family TMEMspv1-c74-12 PF11044.8 RUS83758.1 - 3.1 7.8 7.7 6.2 6.9 0.7 3.3 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Somatomedin_B PF01033.17 RUS83761.1 - 6.7e-06 26.4 18.5 2.8e-05 24.4 18.5 2.2 1 0 0 1 1 1 1 Somatomedin B domain DUF1720 PF08226.11 RUS83762.1 - 0.55 10.7 12.1 2.1 8.8 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1720) Pkinase_Tyr PF07714.17 RUS83764.1 - 6.6e-20 71.5 0.0 1.7e-15 57.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS83764.1 - 3.4e-19 69.2 0.0 5.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Activin_recp PF01064.23 RUS83764.1 - 0.00067 20.7 14.8 0.0023 19.0 14.8 1.9 1 0 0 1 1 1 1 Activin types I and II receptor domain FAD-oxidase_C PF02913.19 RUS83765.1 - 9.7e-23 81.1 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain BBE PF08031.12 RUS83765.1 - 0.026 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.23 RUS83766.1 - 7.7e-37 126.1 0.0 1.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 RUS83766.1 - 8.3e-21 74.7 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Exo_endo_phos PF03372.23 RUS83767.1 - 3.7e-09 36.5 0.0 4.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1_like PF12832.7 RUS83768.1 - 4.6e-91 305.6 15.7 5.5e-91 305.3 15.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 RUS83768.1 - 3.9e-25 88.5 32.9 3.3e-15 55.9 18.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 RUS83768.1 - 2.6e-11 43.1 25.1 3.8e-07 29.4 9.7 3.5 3 1 0 3 3 3 3 Nucleoside H+ symporter LacY_symp PF01306.19 RUS83768.1 - 0.0021 16.9 25.9 0.014 14.2 6.7 3.3 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_3 PF05977.13 RUS83768.1 - 0.013 13.9 4.3 0.013 14.0 1.6 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Ac76 PF05814.11 RUS83768.1 - 0.14 12.2 1.1 9.5 6.3 0.0 3.5 4 0 0 4 4 4 0 Orf76 (Ac76) Pkinase PF00069.25 RUS83769.1 - 4.8e-63 213.0 3.0 6.7e-63 212.5 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83769.1 - 4.1e-43 147.5 0.9 1.3e-42 145.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1475 PF07343.11 RUS83769.1 - 0.084 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) APH PF01636.23 RUS83769.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family SWIRM PF04433.17 RUS83769.1 - 2.1 8.8 7.0 1.7 9.0 0.6 3.2 2 0 0 2 2 2 0 SWIRM domain ABC_membrane PF00664.23 RUS83770.1 - 5.4e-58 196.8 11.2 1.3e-57 195.6 11.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS83770.1 - 1e-34 120.0 0.0 1.8e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS83770.1 - 3.6e-08 33.1 2.3 2.8e-06 26.9 0.1 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 RUS83770.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RUS83770.1 - 0.003 17.3 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS83770.1 - 0.0034 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 RUS83770.1 - 0.0095 15.7 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 RUS83770.1 - 0.014 15.1 0.1 0.06 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RUS83770.1 - 0.035 13.4 0.2 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 RUS83770.1 - 0.035 14.4 0.2 0.23 11.7 0.2 2.3 1 1 0 1 1 1 0 AAA domain MENTAL PF10457.9 RUS83770.1 - 0.048 13.5 4.0 0.11 12.3 4.0 1.5 1 0 0 1 1 1 0 Cholesterol-capturing domain AAA_24 PF13479.6 RUS83770.1 - 0.062 13.0 0.0 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF5305 PF17231.2 RUS83770.1 - 0.22 10.9 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) 7tm_1 PF00001.21 RUS83771.1 - 6e-32 111.0 5.6 7e-32 110.8 5.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS83771.1 - 2.3e-05 23.9 2.5 4.3e-05 23.0 2.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv V_ATPase_I PF01496.19 RUS83772.1 - 0.59 8.0 0.0 0.59 8.0 0.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rer1 PF03248.13 RUS83772.1 - 1.1 9.0 4.3 26 4.5 2.4 2.5 2 1 0 2 2 2 0 Rer1 family Serinc PF03348.15 RUS83772.1 - 3.7 6.4 6.4 21 3.9 6.4 2.0 1 1 0 1 1 1 0 Serine incorporator (Serinc) Lipocalin_2 PF08212.12 RUS83774.1 - 7.5e-25 87.6 0.0 8.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 RUS83774.1 - 1.6e-16 60.8 0.0 1.9e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 RUS83774.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Triabin PDZ PF00595.24 RUS83776.1 - 2.7e-15 56.5 0.4 5.4e-15 55.5 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS83776.1 - 5.8e-07 29.2 0.1 1.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS83776.1 - 0.00086 19.6 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain CCDC-167 PF15188.6 RUS83776.1 - 0.015 15.7 1.4 0.015 15.7 1.4 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TMCO5 PF14992.6 RUS83776.1 - 0.33 10.5 6.9 0.39 10.2 5.8 1.6 1 1 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 RUS83776.1 - 0.84 9.7 4.3 3.9 7.5 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4763 PF15960.5 RUS83776.1 - 1.8 7.8 13.2 9.9 5.4 12.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) zf-MYND PF01753.18 RUS83777.1 - 2e-07 31.0 8.5 6.6e-07 29.3 8.5 1.9 1 0 0 1 1 1 1 MYND finger Sod_Fe_C PF02777.18 RUS83778.1 - 1.5e-34 118.2 0.0 3.2e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RUS83778.1 - 3.2e-31 107.6 2.1 5.1e-31 107.0 2.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Wtap PF17098.5 RUS83779.1 - 8.5e-57 191.5 13.2 8.5e-57 191.5 13.2 2.5 1 1 1 2 2 2 1 WTAP/Mum2p family YabA PF06156.13 RUS83779.1 - 0.00024 21.7 10.0 0.00041 20.9 0.1 3.3 3 0 0 3 3 3 1 Initiation control protein YabA TSC22 PF01166.18 RUS83779.1 - 0.017 15.4 3.5 0.017 15.4 0.1 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 RUS83779.1 - 1.6 9.2 8.2 0.68 10.4 0.6 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4427 PF14468.6 RUS83781.1 - 0.028 14.5 0.5 0.043 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) PFK PF00365.20 RUS83781.1 - 0.26 10.5 3.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Phosphofructokinase ALS2CR8 PF15299.6 RUS83781.1 - 0.54 10.1 5.2 0.76 9.6 5.2 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Adaptin_N PF01602.20 RUS83782.1 - 1.5e-114 383.5 9.0 2.2e-114 382.9 9.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 RUS83782.1 - 5.1e-60 201.1 0.4 1.5e-59 199.5 0.1 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 RUS83782.1 - 9.5e-60 200.5 0.3 2.8e-59 199.0 0.3 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 RUS83782.1 - 1.3e-10 40.6 0.8 0.013 15.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 RUS83782.1 - 9.5e-10 38.7 0.6 0.031 14.7 0.0 5.7 3 3 4 7 7 7 2 HEAT repeats Cnd1 PF12717.7 RUS83782.1 - 1.3e-08 35.1 9.5 2.9e-05 24.2 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS83782.1 - 6.3e-08 33.0 0.4 0.55 10.8 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat Coatomer_g_Cpla PF16381.5 RUS83782.1 - 0.00025 21.1 0.2 0.00076 19.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 RUS83782.1 - 0.00067 19.6 0.3 3.2 7.9 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 RUS83782.1 - 0.0028 17.3 1.9 0.12 12.0 0.0 3.4 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 RUS83782.1 - 0.37 10.2 3.6 1.8 7.9 0.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5578) WD40 PF00400.32 RUS83783.1 - 1.2e-26 92.4 6.7 1.1e-07 32.4 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83783.1 - 1.7e-11 44.3 0.0 0.00064 20.0 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_11 PF13414.6 RUS83783.1 - 2.9e-06 26.8 2.8 2.4e-05 23.9 0.8 2.4 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RUS83783.1 - 7.6e-06 26.0 2.2 0.092 13.2 0.8 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS83783.1 - 9.5e-05 22.1 7.7 0.07 13.0 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS83783.1 - 0.00054 20.6 2.7 0.26 11.9 2.4 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS83783.1 - 0.00096 19.3 4.2 0.25 11.6 2.7 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS83783.1 - 0.0026 18.4 1.5 1.6 9.7 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS83783.1 - 0.0033 17.9 1.0 0.47 11.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS83783.1 - 0.0063 17.0 2.6 0.63 10.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS83783.1 - 0.012 15.7 7.8 0.26 11.5 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RUS83783.1 - 0.063 13.4 0.7 1.4 9.1 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF2A PF08662.11 RUS83783.1 - 0.13 12.1 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Phage_GPL PF05926.11 RUS83783.1 - 0.16 11.9 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) TPR_8 PF13181.6 RUS83783.1 - 0.21 11.9 1.8 44 4.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 RUS83784.1 - 9.4e-13 48.4 12.9 4.6e-06 27.3 0.0 6.1 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83784.1 - 4.9e-05 23.5 0.0 0.22 11.8 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS83784.1 - 0.00069 19.0 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain DUF5046 PF16465.5 RUS83784.1 - 0.004 16.7 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) Nup160 PF11715.8 RUS83784.1 - 0.015 14.0 0.0 4.7 5.7 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS83784.1 - 0.29 10.0 0.6 10 4.9 0.1 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NOT2_3_5 PF04153.18 RUS83785.1 - 5.2e-31 107.5 2.6 8.5e-31 106.8 2.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DnaJ PF00226.31 RUS83786.1 - 5.1e-16 58.6 0.4 5.1e-16 58.6 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain PCI PF01399.27 RUS83787.1 - 2e-10 41.1 0.0 4.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain Fibrinogen_C PF00147.18 RUS83789.1 - 9.9e-40 136.7 3.1 1.4e-39 136.1 3.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ATP-gua_Ptrans PF00217.19 RUS83790.1 - 8.2e-132 437.2 0.4 3.5e-69 232.5 0.1 2.2 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 RUS83790.1 - 2.5e-51 171.9 0.1 8.6e-25 86.9 0.1 2.6 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain TEX33 PF15400.6 RUS83790.1 - 0.047 14.2 0.4 0.53 10.8 0.0 2.7 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family SpuA_C PF18033.1 RUS83790.1 - 0.18 11.9 0.4 23 5.1 0.0 3.5 2 1 0 3 3 3 0 SpuA C-terminal SIR4_SID PF16991.5 RUS83790.1 - 0.33 11.0 6.9 5.2 7.1 2.2 2.6 2 0 0 2 2 2 0 Sir4 SID domain DUF995 PF06191.12 RUS83790.1 - 0.57 9.9 2.2 21 4.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF995) DUF4200 PF13863.6 RUS83791.1 - 1.3e-35 122.3 19.0 1.3e-35 122.3 19.0 5.5 4 2 1 5 5 5 2 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 RUS83791.1 - 0.55 10.3 12.6 1.4 8.9 8.2 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PDZ PF00595.24 RUS83792.1 - 4e-65 216.2 9.5 3.9e-14 52.8 0.1 6.4 6 0 0 6 6 6 6 PDZ domain PDZ_6 PF17820.1 RUS83792.1 - 1.8e-46 155.8 12.7 1.4e-11 44.1 0.0 7.1 7 0 0 7 7 7 6 PDZ domain PDZ_2 PF13180.6 RUS83792.1 - 2.7e-25 88.5 0.6 2.1e-06 28.0 0.0 6.7 6 0 0 6 6 6 6 PDZ domain WW PF00397.26 RUS83792.1 - 6.9e-16 58.0 7.5 4e-08 33.2 0.7 2.8 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 RUS83792.1 - 3.6e-11 43.1 0.0 6.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Carn_acyltransf PF00755.20 RUS83796.1 - 3.2e-92 310.0 0.0 4.3e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sugar_tr PF00083.24 RUS83797.1 - 5.2e-24 84.9 21.5 1.4e-22 80.2 21.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS83797.1 - 2.7e-18 66.0 48.9 5.7e-17 61.7 25.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2316 PF10078.9 RUS83797.1 - 0.0016 18.7 0.7 10 6.5 0.1 3.2 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2316) TGT_C1 PF14809.6 RUS83797.1 - 0.058 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation LRR_6 PF13516.6 RUS83798.1 - 1.8e-09 36.9 1.4 69 3.9 0.0 8.5 2 2 7 9 9 9 0 Leucine Rich repeat N2227 PF07942.12 RUS83798.1 - 0.26 10.5 2.4 51 2.9 0.1 3.3 1 1 3 4 4 4 0 N2227-like protein Phage_tail_2 PF06199.11 RUS83798.1 - 0.35 10.9 5.0 6.4 6.9 0.1 3.3 1 1 2 3 3 3 0 Phage tail tube protein BNR PF02012.20 RUS83798.1 - 8.1 6.9 26.1 1.5e+02 3.1 0.1 7.7 8 0 0 8 8 8 0 BNR/Asp-box repeat OLF PF02191.16 RUS83799.1 - 5.5e-39 134.2 0.0 7.4e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 RUS83799.1 - 7.6e-18 64.0 70.2 8.4e-09 35.1 28.0 3.4 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) DUF2316 PF10078.9 RUS83799.1 - 0.036 14.3 0.1 16 5.8 0.0 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Maf_N PF08383.11 RUS83799.1 - 1.9 8.4 10.4 78 3.2 0.1 5.3 1 1 4 6 6 6 0 Maf N-terminal region Defensin_int PF17858.1 RUS83800.1 - 1.2 9.1 11.9 6.1 6.9 5.5 3.7 2 1 1 3 3 3 0 Platypus intermediate defensin-like peptide Prok_Ub PF14454.6 RUS83800.1 - 6.6 6.5 6.3 22 4.8 0.1 3.4 4 0 0 4 4 4 0 Prokaryotic Ubiquitin Toxin_22 PF08092.11 RUS83800.1 - 9.2 6.4 16.8 6.2 7.0 4.3 3.7 2 1 2 4 4 4 0 Magi peptide toxin family MOZART1 PF12554.8 RUS83801.1 - 1.3 8.9 6.9 25 4.8 0.1 4.4 2 1 3 5 5 5 0 Mitotic-spindle organizing gamma-tubulin ring associated RVT_1 PF00078.27 RUS83802.1 - 6.6e-37 127.2 0.3 9.5e-37 126.7 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Taxilin PF09728.9 RUS83802.1 - 0.1 11.8 7.4 0.18 11.0 7.4 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein EMP70 PF02990.16 RUS83803.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Fez1 PF06818.15 RUS83803.1 - 0.055 13.9 0.3 5 7.5 0.1 2.1 2 0 0 2 2 2 0 Fez1 T4BSS_DotI_IcmL PF11393.8 RUS83804.1 - 0.17 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component PRELI PF04707.14 RUS83805.1 - 2.1e-51 173.9 0.0 2.7e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF5446 PF17522.2 RUS83805.1 - 0.042 14.0 0.2 0.091 12.9 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Tachylectin PF14517.6 RUS83805.1 - 0.075 12.6 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 Tachylectin MARVEL PF01284.23 RUS83806.1 - 2.1e-09 37.6 21.7 7.2e-09 35.8 21.1 1.9 1 1 1 2 2 2 1 Membrane-associating domain DUF4231 PF14015.6 RUS83806.1 - 0.41 11.1 4.4 0.83 10.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2070 PF09843.9 RUS83806.1 - 2.6 6.2 9.6 2.9 6.1 9.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VPS9 PF02204.18 RUS83807.1 - 1.5e-26 92.7 0.3 1.6e-25 89.3 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MIT PF04212.18 RUS83807.1 - 0.002 18.2 0.6 0.016 15.2 0.1 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain LsmAD PF06741.13 RUS83807.1 - 1.7 9.2 4.9 10 6.8 1.1 3.1 2 0 0 2 2 2 0 LsmAD domain Laminin_G_1 PF00054.23 RUS83809.1 - 4.8e-71 237.1 0.2 4.1e-26 91.7 0.1 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 RUS83809.1 - 2.8e-69 231.5 2.1 9.7e-25 87.6 0.1 3.3 3 0 0 3 3 3 3 Laminin G domain Kazal_2 PF07648.15 RUS83809.1 - 1.2e-64 214.2 124.7 2.6e-10 40.3 5.4 11.4 10 1 0 10 10 10 8 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS83809.1 - 5.6e-48 160.7 113.6 3.5e-09 36.5 7.5 9.7 8 0 0 8 8 8 8 Kazal-type serine protease inhibitor domain Laminin_EGF PF00053.24 RUS83809.1 - 3.8e-15 55.7 29.9 2.9e-10 40.1 10.2 15.6 13 4 3 16 16 16 3 Laminin EGF domain Laminin_G_3 PF13385.6 RUS83809.1 - 7.4e-10 39.2 0.0 0.0022 18.2 0.1 3.3 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RUS83809.1 - 1.4e-09 38.1 29.6 1.1e-05 25.7 3.9 16.2 14 0 0 14 14 14 6 EGF-like domain NtA PF03146.15 RUS83810.1 - 1.8e-28 98.6 0.2 2.3e-28 98.2 0.2 1.1 1 0 0 1 1 1 1 Agrin NtA domain TIMP PF00965.17 RUS83810.1 - 0.029 14.2 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase MFS_1 PF07690.16 RUS83811.1 - 6e-32 110.9 8.1 4.1e-24 85.2 3.3 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF998 PF06197.13 RUS83811.1 - 0.0014 18.2 9.9 0.32 10.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF998) RRP14 PF15459.6 RUS83811.1 - 0.073 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 EI24 PF07264.11 RUS83811.1 - 0.58 10.4 12.2 2.4 8.4 4.2 3.3 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) UL42 PF17638.2 RUS83811.1 - 1.9 8.5 3.9 2.1 8.3 0.0 2.8 2 1 1 3 3 3 0 HCMV UL42 SLT PF01464.20 RUS83812.1 - 0.0006 19.4 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 2 Transglycosylase SLT domain RUN PF02759.19 RUS83813.1 - 4.5e-22 78.5 1.1 7e-22 77.8 1.1 1.3 1 0 0 1 1 1 1 RUN domain zf-RING_9 PF13901.6 RUS83814.1 - 4e-62 209.9 14.7 4e-62 209.9 14.7 1.6 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RRM_5 PF13893.6 RUS83816.1 - 4e-49 165.4 5.1 4.9e-33 113.4 0.0 4.2 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RUS83816.1 - 3.8e-30 103.5 0.6 1.6e-06 27.8 0.1 5.4 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RUS83816.1 - 2e-12 47.1 0.0 7.8e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 RUS83816.1 - 8.6e-09 35.1 0.4 0.23 11.3 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif Spt20 PF12090.8 RUS83816.1 - 0.11 12.0 6.8 0.27 10.8 6.8 1.6 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 RUS83816.1 - 0.19 11.5 3.0 0.48 10.2 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2967 PF11179.8 RUS83816.1 - 0.67 8.0 3.9 1.1 7.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Cor1 PF04803.12 RUS83817.1 - 0.00011 22.4 5.5 0.06 13.6 1.8 2.4 1 1 1 2 2 2 2 Cor1/Xlr/Xmr conserved region Wx5_PLAF3D7 PF09688.10 RUS83817.1 - 0.00041 20.4 12.0 0.049 13.6 6.4 2.9 1 1 2 3 3 3 3 Protein of unknown function (Wx5_PLAF3D7) zf-ACC PF17848.1 RUS83817.1 - 0.00086 19.3 3.4 7.2 6.8 0.0 4.4 4 0 0 4 4 4 1 Acetyl-coA carboxylase zinc finger domain Lipase_2 PF01674.18 RUS83817.1 - 0.01 15.4 5.9 0.1 12.1 0.3 2.0 1 1 1 2 2 2 2 Lipase (class 2) FAA_hydrolase_N PF09298.11 RUS83817.1 - 0.011 15.9 0.0 6.5 7.0 0.0 2.9 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal Rota_VP4_MID PF17477.2 RUS83817.1 - 0.012 15.0 1.4 0.82 9.0 0.2 2.4 1 1 1 2 2 2 0 Rotavirus VP4 membrane interaction domain eRF1_2 PF03464.15 RUS83817.1 - 0.027 14.8 0.1 2.7 8.3 0.0 2.2 1 1 1 2 2 2 0 eRF1 domain 2 DUF3942 PF13078.6 RUS83817.1 - 0.027 14.8 0.7 4.1 7.7 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3942) 2-oxogl_dehyd_N PF16078.5 RUS83817.1 - 0.034 13.7 0.4 9.6 5.9 0.0 3.1 2 1 1 3 3 3 0 2-oxoglutarate dehydrogenase N-terminus CSF-1 PF05337.11 RUS83817.1 - 0.064 13.4 3.4 0.83 9.8 1.5 2.6 1 1 1 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) SpoVAD PF07451.11 RUS83817.1 - 0.075 11.7 1.1 0.93 8.1 0.4 2.5 1 1 2 3 3 3 0 Stage V sporulation protein AD (SpoVAD) MT-A70 PF05063.14 RUS83819.1 - 1.2e-33 116.4 0.2 2.3e-33 115.5 0.2 1.5 1 0 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 RUS83819.1 - 0.0064 16.3 0.0 0.048 13.5 0.0 2.0 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase Tho2 PF11262.8 RUS83819.1 - 0.25 10.5 1.4 0.36 10.0 1.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2799 PF10973.8 RUS83820.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) Ion_trans PF00520.31 RUS83821.1 - 5e-39 134.0 14.8 6.7e-39 133.6 14.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS83821.1 - 3.3e-10 39.8 8.8 3.3e-10 39.8 8.8 2.0 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.22 RUS83821.1 - 0.00013 22.2 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF5090 PF17009.5 RUS83821.1 - 8.8 6.2 12.2 16 5.4 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF4313 PF14190.6 RUS83822.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Reprolysin_2 PF13574.6 RUS83823.1 - 1.6e-17 64.0 0.0 4.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS83823.1 - 4.2e-17 62.9 0.0 1.1e-16 61.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 RUS83823.1 - 8.2e-09 36.1 17.4 8.2e-09 36.1 17.4 3.3 2 1 1 3 3 3 1 Disintegrin Reprolysin PF01421.19 RUS83823.1 - 3.3e-07 30.4 0.1 4.6e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 RUS83823.1 - 5.6e-06 26.9 0.1 1.5e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS83823.1 - 6.2e-06 26.5 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 RUS83823.1 - 0.00018 21.2 0.3 0.00046 19.9 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Glyco_transf_92 PF01697.27 RUS83824.1 - 1.2e-31 110.3 0.1 1.6e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Pkinase PF00069.25 RUS83826.1 - 3.5e-53 180.7 0.1 8.5e-53 179.4 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83826.1 - 2.2e-41 141.9 0.0 4.6e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 RUS83826.1 - 4.4e-24 84.5 1.8 1.1e-23 83.1 1.8 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain CUB PF00431.20 RUS83827.1 - 8.9e-06 26.0 1.3 0.069 13.5 0.3 2.3 2 0 0 2 2 2 2 CUB domain EPTP PF03736.17 RUS83827.1 - 0.018 15.0 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 EPTP domain Filamin PF00630.19 RUS83827.1 - 0.032 15.0 0.2 13 6.6 0.0 2.7 2 1 1 3 3 3 0 Filamin/ABP280 repeat EMP24_GP25L PF01105.24 RUS83827.1 - 0.073 13.0 1.7 7.5 6.4 0.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FtsX PF02687.21 RUS83828.1 - 0.017 15.6 0.5 5.6 7.5 0.2 2.2 2 0 0 2 2 2 0 FtsX-like permease family EphA2_TM PF14575.6 RUS83828.1 - 0.02 15.8 0.0 0.061 14.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UL45 PF05473.12 RUS83828.1 - 0.035 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Orf78 PF06024.12 RUS83828.1 - 0.038 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Rax2 PF12768.7 RUS83828.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Podoplanin PF05808.11 RUS83828.1 - 0.087 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin DUF4448 PF14610.6 RUS83828.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3827 PF12877.7 RUS83828.1 - 0.19 10.0 1.1 0.32 9.3 0.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) Wzy_C PF04932.15 RUS83828.1 - 2.7 7.6 4.0 4.4 6.9 0.6 2.2 2 0 0 2 2 2 0 O-Antigen ligase DUF4486 PF14858.6 RUS83829.1 - 2.3e-228 759.1 0.0 2.7e-228 758.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) fn3 PF00041.21 RUS83830.1 - 0.0055 17.0 0.1 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain FAM72 PF14976.6 RUS83831.1 - 3.9e-42 143.8 5.7 4.5e-42 143.6 5.7 1.0 1 0 0 1 1 1 1 FAM72 protein SPA PF08616.10 RUS83833.1 - 1.2e-15 57.4 0.1 2.5e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 RUS83833.1 - 1.5e-07 31.5 3.3 2.1e-06 27.8 3.3 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.9 RUS83833.1 - 3.7e-05 22.6 0.0 6.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 FHA PF00498.26 RUS83834.1 - 4e-16 59.1 0.0 1.1e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Fez1 PF06818.15 RUS83834.1 - 0.00035 21.1 34.0 0.00035 21.1 34.0 6.1 3 2 3 6 6 6 2 Fez1 IFT57 PF10498.9 RUS83834.1 - 0.00087 18.4 8.7 0.00087 18.4 8.7 5.6 3 2 1 5 5 5 3 Intra-flagellar transport protein 57 Yop-YscD_cpl PF16697.5 RUS83834.1 - 0.0055 17.0 0.0 0.047 14.0 0.0 2.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Spc7 PF08317.11 RUS83834.1 - 0.051 12.5 140.4 0.0081 15.1 21.6 6.6 3 2 4 7 7 7 0 Spc7 kinetochore protein Filament PF00038.21 RUS83834.1 - 1.1 8.8 120.9 0.13 11.9 14.5 6.1 2 2 3 5 5 5 0 Intermediate filament protein ATG16 PF08614.11 RUS83834.1 - 3.9 7.6 143.0 0.14 12.4 10.5 7.5 2 2 5 7 7 7 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 RUS83834.1 - 8.4 4.4 107.6 0.0076 14.5 16.8 5.0 3 2 0 4 4 4 0 Septation ring formation regulator, EzrA G-patch PF01585.23 RUS83835.1 - 1.3e-10 41.0 1.2 2.3e-10 40.2 1.2 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 RUS83835.1 - 3e-05 23.8 0.1 7.5e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_13 PF13880.6 RUS83836.1 - 1.5e-23 82.5 0.0 3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 RUS83836.1 - 9.7e-17 60.5 2.3 2.1e-16 59.5 2.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 RUS83836.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1704 PF08014.11 RUS83836.1 - 0.16 10.9 1.5 0.29 10.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Cadherin_C_2 PF16492.5 RUS83837.1 - 0.036 14.8 0.1 0.11 13.3 0.1 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 RUS83837.1 - 0.053 14.4 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS83837.1 - 0.09 13.0 1.2 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 RUS83837.1 - 0.097 12.4 3.3 0.16 11.8 3.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RUS83837.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.0 3 0 0 3 3 3 0 TMEM154 protein family Herpes_gE PF02480.16 RUS83837.1 - 0.26 10.0 1.3 1.2 7.8 0.3 2.4 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 RUS83837.1 - 8.8 5.6 8.0 2.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Filamin PF00630.19 RUS83838.1 - 0.035 14.9 0.0 0.064 14.1 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat BTB_2 PF02214.22 RUS83839.1 - 7.7e-17 61.4 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RUS83839.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain PI3_PI4_kinase PF00454.27 RUS83841.1 - 1.5e-54 185.4 0.0 3e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 RUS83841.1 - 1.4e-46 159.3 5.4 1.4e-46 159.3 5.4 3.1 4 0 0 4 4 4 1 FAT domain UME PF08064.13 RUS83841.1 - 1.1e-15 57.4 8.6 9e-14 51.2 0.3 5.5 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.20 RUS83841.1 - 1.8e-14 53.3 0.0 4.3e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 RUS83841.1 - 4.2e-05 23.5 10.1 5.6 7.5 0.1 7.4 7 0 0 7 7 7 1 HEAT repeat TPR_14 PF13428.6 RUS83841.1 - 0.00011 22.7 5.2 4.7 8.3 0.0 6.5 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS83841.1 - 0.00014 21.8 0.1 0.069 13.4 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS83841.1 - 0.0023 17.7 0.8 0.025 14.4 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS83841.1 - 0.0032 17.1 0.1 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 TPR repeat LepB_GAP_C PF18227.1 RUS83841.1 - 0.0073 16.8 0.1 0.21 12.1 0.1 3.0 2 0 0 2 2 2 1 LepB GAP domain C-terminal subdomain Cnd1 PF12717.7 RUS83841.1 - 0.0081 16.2 8.0 0.22 11.6 0.4 4.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TPR_2 PF07719.17 RUS83841.1 - 0.011 15.7 9.5 0.087 13.0 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Ion_trans_N PF08412.10 RUS83841.1 - 0.021 14.4 0.1 0.68 9.6 0.2 3.0 3 0 0 3 3 3 0 Ion transport protein N-terminal TPR_7 PF13176.6 RUS83841.1 - 0.034 14.2 0.4 1 9.6 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 RUS83841.1 - 0.081 13.1 1.2 12 6.1 0.0 3.9 3 0 0 3 3 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_17 PF13431.6 RUS83841.1 - 0.11 12.9 0.0 4.8 7.8 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS83841.1 - 0.64 9.2 5.8 0.17 11.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3385 PF11865.8 RUS83842.1 - 0.048 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Arf PF00025.21 RUS83843.1 - 9.1e-44 149.0 0.3 1.1e-43 148.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS83843.1 - 8.4e-13 48.6 0.1 1.4e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RUS83843.1 - 8.9e-12 44.8 0.8 4e-08 32.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RUS83843.1 - 1.5e-11 44.1 0.1 1.9e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS83843.1 - 5.9e-07 29.1 0.2 7.1e-07 28.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS83843.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS83843.1 - 4e-06 26.9 0.0 5.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 RUS83843.1 - 0.14 11.7 1.5 10 5.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-CCHC_3 PF13917.6 RUS83844.1 - 1.1e-07 31.6 0.1 2.5e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle CpXC PF14353.6 RUS83844.1 - 0.53 10.3 4.3 1 9.4 4.1 1.9 1 1 0 1 1 1 0 CpXC protein Raftlin PF15250.6 RUS83844.1 - 3.8 6.1 21.0 4.4 5.9 21.0 1.1 1 0 0 1 1 1 0 Raftlin NUDIX PF00293.28 RUS83845.1 - 1.2e-17 64.2 0.2 1.4e-17 64.0 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain SAM_Ste50p PF09235.10 RUS83846.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Ank_2 PF12796.7 RUS83847.1 - 2.8e-59 197.7 20.8 1.1e-12 48.3 0.4 6.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS83847.1 - 3.2e-47 158.0 27.2 2.1e-08 34.3 0.1 11.3 5 4 7 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS83847.1 - 2.9e-45 152.1 18.5 9.8e-08 32.4 2.4 7.7 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS83847.1 - 3.4e-42 141.1 26.1 7e-07 29.4 0.4 10.9 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 RUS83847.1 - 1.4e-40 132.6 16.3 0.00078 19.7 0.1 11.7 11 1 1 12 12 12 10 Ankyrin repeat Y_phosphatase PF00102.27 RUS83847.1 - 0.034 13.7 0.2 0.11 12.1 0.1 1.8 1 1 1 2 2 2 0 Protein-tyrosine phosphatase Ion_trans PF00520.31 RUS83848.1 - 1.2e-06 28.0 20.8 1.6e-06 27.6 20.8 1.2 1 0 0 1 1 1 1 Ion transport protein Tad PF13400.6 RUS83848.1 - 0.0056 17.0 0.6 0.0056 17.0 0.6 2.4 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like Bac_export_3 PF01313.19 RUS83848.1 - 0.029 14.3 1.8 0.029 14.3 1.8 2.5 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Antigen_Bd37 PF11641.8 RUS83848.1 - 0.12 11.8 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF4083 PF13314.6 RUS83848.1 - 0.33 10.9 4.8 7.9 6.5 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) SAM_1 PF00536.30 RUS83850.1 - 0.0089 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1908 PF08926.11 RUS83851.1 - 7.3e-115 382.9 0.0 7.3e-115 382.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 RUS83851.1 - 2e-61 207.7 0.0 4.4e-61 206.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83851.1 - 6.3e-26 91.2 0.0 1.3e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 RUS83851.1 - 5.7e-08 32.5 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS83851.1 - 2e-06 28.0 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS83851.1 - 2.7e-05 24.5 0.0 6.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 RUS83851.1 - 0.00035 20.6 0.0 0.085 12.8 0.0 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS83851.1 - 0.0015 17.9 0.0 0.0064 15.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RUS83851.1 - 0.032 13.2 0.1 0.086 11.8 0.1 1.8 1 0 0 1 1 1 0 Haspin like kinase domain FKBP_C PF00254.28 RUS83852.1 - 9e-34 115.7 0.0 1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NAGLU_N PF12971.7 RUS83853.1 - 7.5e-22 76.9 0.0 1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF4752 PF15944.5 RUS83853.1 - 0.16 12.1 0.5 0.68 10.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4752) NAGLU PF05089.12 RUS83854.1 - 3e-124 414.3 1.1 4.5e-124 413.7 1.1 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 RUS83854.1 - 1.2e-74 251.2 7.6 1.9e-74 250.6 7.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain CoA_trans PF01144.23 RUS83855.1 - 4e-123 408.8 4.6 1.2e-76 256.9 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 RUS83855.1 - 1.1e-05 25.4 0.4 2.1e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 RUS83855.1 - 0.015 13.7 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Syntaxin PF00804.25 RUS83856.1 - 6.4e-28 97.8 11.3 6.4e-28 97.8 11.3 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 RUS83856.1 - 9.6e-15 54.3 2.6 2.9e-14 52.8 2.6 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 RUS83856.1 - 1.1e-05 25.7 2.7 1.1e-05 25.7 2.7 2.6 3 0 0 3 3 3 1 Syntaxin-like protein DUF2207 PF09972.9 RUS83856.1 - 0.032 13.0 4.8 0.12 11.2 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 RUS83856.1 - 0.038 14.0 0.3 0.064 13.2 0.3 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Herpes_US9 PF06072.11 RUS83856.1 - 0.089 12.7 0.7 0.26 11.2 0.7 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Med7 PF05983.11 RUS83856.1 - 1.8 8.6 6.7 3.5 7.7 5.5 2.3 1 1 1 2 2 2 0 MED7 protein Phage_GP20 PF06810.11 RUS83856.1 - 2.2 8.1 9.7 0.24 11.2 0.3 3.1 1 1 1 3 3 3 0 Phage minor structural protein GP20 Uso1_p115_C PF04871.13 RUS83856.1 - 2.3 8.6 10.0 0.34 11.3 0.4 2.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 RUS83856.1 - 9.7 5.7 11.6 36 3.8 11.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.16 RUS83857.1 - 3.6e-31 109.0 0.2 1.2e-30 107.4 0.2 1.9 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS83857.1 - 1.3e-19 70.6 0.9 3.1e-19 69.3 0.9 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain 7tm_1 PF00001.21 RUS83857.1 - 8.9e-08 31.8 10.2 1.4e-06 27.9 8.3 2.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PspB PF06667.12 RUS83857.1 - 0.91 9.6 6.8 0.41 10.7 0.6 2.9 3 0 0 3 3 3 0 Phage shock protein B Homeodomain PF00046.29 RUS83859.1 - 3.2e-08 33.3 4.0 8.8e-08 31.9 4.0 1.8 1 0 0 1 1 1 1 Homeodomain HNF-1_N PF04814.13 RUS83859.1 - 5e-06 27.3 0.9 5e-06 27.3 0.9 2.9 2 2 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox_KN PF05920.11 RUS83859.1 - 0.0028 17.5 1.7 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain RPA43_OB PF17875.1 RUS83860.1 - 8 7.1 7.9 18 5.9 0.1 3.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF624 PF04854.14 RUS83861.1 - 0.15 12.2 0.1 3 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 zf-B_box PF00643.24 RUS83862.1 - 0.00087 19.4 54.4 1.7 8.9 6.5 6.6 1 1 6 7 7 7 5 B-box zinc finger Cdc6_C PF09079.11 RUS83862.1 - 0.017 15.1 14.6 10 6.2 0.4 5.5 1 1 3 4 4 4 0 CDC6, C terminal winged helix domain RII_binding_1 PF10522.9 RUS83862.1 - 0.024 14.8 19.0 2.6e+02 2.3 0.1 9.9 12 0 0 12 12 12 0 RII binding domain DNA_binding_1 PF01035.20 RUS83862.1 - 0.044 13.9 1.2 10 6.3 0.1 3.3 1 1 0 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_AraC PF00165.23 RUS83862.1 - 0.52 10.5 8.7 18 5.6 0.0 5.4 3 3 5 9 9 9 0 Bacterial regulatory helix-turn-helix proteins, AraC family ABC_tran PF00005.27 RUS83863.1 - 2.7e-09 37.7 0.0 6.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS83863.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain HRI1 PF16815.5 RUS83863.1 - 0.0079 15.9 0.0 0.0085 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein HRI1 Glyco_transf_7N PF13733.6 RUS83864.1 - 7.2e-40 135.7 0.0 1.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS83864.1 - 7.6e-21 73.6 0.2 1.5e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase INCENP_ARK-bind PF03941.15 RUS83865.1 - 3.1e-16 59.0 1.4 1.4e-15 57.0 1.4 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Ank_2 PF12796.7 RUS83866.1 - 2.3e-25 89.0 0.2 2.1e-11 44.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS83866.1 - 4.1e-22 75.9 3.2 0.018 15.5 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 RUS83866.1 - 1.6e-15 57.2 0.8 9.5e-06 26.1 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS83866.1 - 1.1e-12 47.8 4.9 0.011 16.2 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RUS83866.1 - 5.2e-12 45.7 2.8 0.00018 21.7 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NUDIX PF00293.28 RUS83867.1 - 2e-16 60.2 0.1 3.5e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain MPC PF03650.13 RUS83868.1 - 2.8e-41 140.1 0.1 3.6e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 RUS83868.1 - 0.046 13.8 0.2 0.059 13.4 0.2 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange HS1_rep PF02218.15 RUS83869.1 - 5.7e-104 340.1 60.3 1.5e-20 73.2 6.7 6.5 6 0 0 6 6 6 6 Repeat in HS1/Cortactin SH3_9 PF14604.6 RUS83869.1 - 6.5e-18 64.3 0.3 1.6e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS83869.1 - 1.4e-17 63.0 0.1 2.9e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS83869.1 - 7.3e-10 38.4 0.0 1.7e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 RUS83869.1 - 4.8e-07 30.2 5.7 7.2 7.1 0.0 6.1 1 1 5 6 6 6 2 TMEM210 family TonB_N PF16031.5 RUS83869.1 - 0.2 12.2 36.8 0.19 12.2 35.4 1.6 1 1 0 1 1 1 0 TonB polyproline region Trypan_PARP PF05887.11 RUS83869.1 - 3.5 7.6 62.2 29 4.6 57.9 3.1 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) His_Phos_1 PF00300.22 RUS83870.1 - 7.5e-38 130.2 2.0 1.7e-35 122.5 0.6 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glyco_transf_7N PF13733.6 RUS83871.1 - 4.7e-42 142.8 0.0 7.7e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS83871.1 - 1.1e-20 73.0 0.4 2.2e-20 72.1 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase LisH_TPL PF17814.1 RUS83874.1 - 0.055 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 LisH-like dimerisation domain Utp14 PF04615.13 RUS83875.1 - 0.38 9.3 2.9 0.49 8.9 2.9 1.1 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 RUS83875.1 - 1.2 7.2 19.6 1.5 6.9 19.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RUS83875.1 - 3.5 6.9 31.3 5.7 6.2 31.3 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_47 PF01532.20 RUS83877.1 - 5.5e-153 510.1 0.5 7.2e-153 509.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Spc7 PF08317.11 RUS83878.1 - 0.23 10.3 10.5 0.42 9.4 10.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Mt_ATP_synt PF15704.5 RUS83878.1 - 0.97 9.3 8.2 0.14 12.0 2.6 2.3 2 1 1 3 3 3 0 Mitochondrial ATP synthase subunit Sec2p PF06428.11 RUS83878.1 - 1.1 9.3 18.4 0.078 13.0 8.9 3.2 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF1640 PF07798.11 RUS83878.1 - 5.3 7.1 13.2 1.5 8.9 8.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) zf-CCHC PF00098.23 RUS83879.1 - 6.8e-06 25.9 12.0 0.0035 17.4 1.8 2.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS83879.1 - 0.041 13.7 7.6 0.042 13.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle BUD22 PF09073.10 RUS83880.1 - 0.93 8.8 63.0 1.4 8.1 63.0 1.3 1 0 0 1 1 1 0 BUD22 Glyco_transf_54 PF04666.13 RUS83881.1 - 2.5e-120 400.8 0.0 3.4e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region TSKS PF15358.6 RUS83881.1 - 0.062 11.7 1.2 0.093 11.1 1.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Sugarporin_N PF11471.8 RUS83881.1 - 1.4 8.9 5.9 0.28 11.2 1.3 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Glyco_transf_54 PF04666.13 RUS83883.1 - 6.6e-53 179.5 5.4 8.8e-53 179.1 5.4 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Plasmod_dom_1 PF09715.10 RUS83883.1 - 0.096 12.8 0.1 0.35 10.9 0.1 2.0 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) zf-CCHC_3 PF13917.6 RUS83884.1 - 4.7e-13 48.9 4.0 7.9e-13 48.2 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle NOA36 PF06524.12 RUS83884.1 - 0.6 9.4 25.9 0.67 9.2 25.9 1.0 1 0 0 1 1 1 0 NOA36 protein Rrn6 PF10214.9 RUS83884.1 - 4 5.8 23.8 4.3 5.7 23.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop14 PF04147.12 RUS83884.1 - 7.1 4.7 28.3 7.9 4.6 28.3 1.0 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.16 RUS83884.1 - 7.6 6.5 8.6 9.1 6.3 8.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AA_permease_2 PF13520.6 RUS83885.1 - 2.2e-65 221.1 44.7 2.2e-65 221.1 44.7 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS83885.1 - 2.1e-32 112.3 42.3 2.7e-32 112.0 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_64 PF09258.10 RUS83886.1 - 5.9e-89 297.5 0.0 8.5e-89 297.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 RUS83886.1 - 6.3e-49 166.8 0.0 8.3e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Exostosin family DUF1981 PF09324.10 RUS83887.1 - 9.3e-09 35.0 0.6 7.2e-08 32.2 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) QSregVF PF13652.6 RUS83887.1 - 0.0081 16.2 0.5 0.031 14.3 0.2 2.0 2 0 0 2 2 2 1 Putative quorum-sensing-regulated virulence factor Sec7_N PF12783.7 RUS83889.1 - 0.0045 16.9 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_pol_A PF00476.20 RUS83890.1 - 3.5e-107 358.7 0.0 8.7e-107 357.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family A DEAD PF00270.29 RUS83890.1 - 2.7e-18 66.3 0.0 8.7e-17 61.4 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS83890.1 - 9.4e-15 54.9 1.1 1.4e-10 41.5 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4332 PF14229.6 RUS83890.1 - 0.0084 16.3 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) TIMP PF00965.17 RUS83890.1 - 0.021 14.6 0.1 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Tissue inhibitor of metalloproteinase SP24 PF16504.5 RUS83891.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus Sod_Cu PF00080.20 RUS83892.1 - 2.8e-53 179.9 4.5 3.2e-53 179.7 4.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 RUS83892.1 - 0.0015 19.5 1.9 0.002 19.1 1.8 1.3 1 1 0 1 1 1 1 CHRD domain 7tm_1 PF00001.21 RUS83893.1 - 2.7e-29 102.3 11.4 3.6e-29 101.9 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS83893.1 - 1.8e-05 24.6 4.9 1.8e-05 24.6 4.9 2.0 2 1 1 3 3 3 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS83893.1 - 0.0047 16.3 11.8 0.014 14.7 11.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS83894.1 - 6.8e-28 97.7 6.1 9.7e-28 97.2 6.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS83894.1 - 1.9e-09 37.3 10.1 1.1e-05 25.0 3.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS83894.1 - 0.0056 16.3 8.8 0.0056 16.3 8.8 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SNARE PF05739.19 RUS83894.1 - 0.0093 15.9 1.3 0.51 10.4 0.1 3.0 2 0 0 2 2 2 1 SNARE domain Podoplanin PF05808.11 RUS83894.1 - 0.017 15.2 0.7 0.017 15.2 0.7 2.0 2 0 0 2 2 2 0 Podoplanin UPF0715 PF17094.5 RUS83894.1 - 0.08 13.5 5.3 0.49 11.0 1.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) CTU2 PF10288.9 RUS83894.1 - 0.37 11.0 2.6 0.84 9.9 2.6 1.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PetG PF02529.15 RUS83894.1 - 1.5 8.7 6.2 2.7 7.9 0.1 3.8 4 0 0 4 4 4 0 Cytochrome B6-F complex subunit 5 7tm_1 PF00001.21 RUS83895.1 - 2.5e-24 86.0 11.9 3.5e-24 85.6 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS83895.1 - 7.8e-11 41.8 12.0 3.6e-10 39.7 12.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS83895.1 - 5.8e-05 22.8 12.0 5.8e-05 22.8 12.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Shadoo PF14999.6 RUS83896.1 - 0.46 10.6 8.1 9.6 6.3 0.7 2.9 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective V_ATPase_I PF01496.19 RUS83896.1 - 0.77 7.6 4.8 1.3 6.8 4.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAGH_C PF16123.5 RUS83898.1 - 0.66 10.5 10.4 0.058 13.9 1.2 3.7 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Adap_comp_sub PF00928.21 RUS83899.1 - 2.8e-46 158.0 0.1 3.3e-33 115.2 0.0 2.4 2 1 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS83899.1 - 4.5e-09 36.4 0.2 8.1e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec6 PF06046.13 RUS83899.1 - 0.08 11.3 0.2 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 EGF PF00008.27 RUS83900.1 - 2.9e-05 24.3 31.7 0.012 15.9 6.4 3.7 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 RUS83900.1 - 0.41 10.9 24.1 0.73 10.1 0.9 3.8 3 0 0 3 3 3 0 EGF domain Carb_anhydrase PF00194.21 RUS83901.1 - 3.2e-81 272.6 2.6 3.5e-53 180.7 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 RUS83902.1 - 2.7e-51 174.6 0.0 3e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Fibrinogen_C PF00147.18 RUS83903.1 - 6.8e-58 196.1 5.9 9.9e-58 195.5 5.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain MtrG PF04210.13 RUS83903.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G AKAP7_NLS PF10469.9 RUS83904.1 - 2.8e-31 109.0 0.1 2.8e-31 109.0 0.1 2.2 2 1 1 3 3 3 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 RUS83904.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 RUS83904.1 - 0.00015 21.9 0.0 0.82 9.9 0.0 2.6 2 0 0 2 2 2 2 LigT like Phosphoesterase CobT PF06213.12 RUS83904.1 - 0.12 11.7 4.7 0.18 11.2 4.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_A21 PF03566.13 RUS83904.1 - 0.53 8.5 2.9 0.73 8.0 2.9 1.1 1 0 0 1 1 1 0 Peptidase family A21 Pkinase PF00069.25 RUS83905.1 - 1.8e-34 119.3 0.2 6.9e-26 91.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS83905.1 - 2.3e-12 46.7 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS83905.1 - 0.0012 18.8 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1472 PF07339.12 RUS83905.1 - 0.11 13.0 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) Pkinase_fungal PF17667.1 RUS83905.1 - 0.13 11.0 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RUS83905.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fibrinogen_C PF00147.18 RUS83906.1 - 8.9e-56 189.1 5.3 1.2e-55 188.7 5.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Lectin_C PF00059.21 RUS83907.1 - 5e-16 59.4 0.0 6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS83908.1 - 6.8e-13 49.3 0.0 8.5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain p450 PF00067.22 RUS83909.1 - 2.5e-105 352.9 0.0 3.7e-105 352.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 VASt PF16016.5 RUS83911.1 - 4.7e-21 75.8 0.0 5.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain IFT46_B_C PF12317.8 RUS83913.1 - 6.7e-101 336.4 1.8 7.8e-101 336.2 1.8 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal MatP PF06303.12 RUS83913.1 - 0.039 14.5 0.7 0.12 12.9 0.2 2.0 3 0 0 3 3 3 0 MatP N-terminal domain LuxE PF04443.12 RUS83913.1 - 0.11 11.5 0.3 0.15 11.0 0.3 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE TGS PF02824.21 RUS83914.1 - 3.6e-06 26.9 0.0 1.1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 TGS domain DUF1442 PF07279.11 RUS83914.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) TPH PF13868.6 RUS83915.1 - 2.6e-86 289.3 135.7 2.6e-86 289.3 135.7 2.6 2 1 1 3 3 3 1 Trichohyalin-plectin-homology domain RITA PF17066.5 RUS83915.1 - 0.0067 16.1 1.4 0.022 14.4 0.0 2.4 2 0 0 2 2 2 1 RBPJ-interacting and tubulin associated protein Activator_LAG-3 PF11498.8 RUS83919.1 - 0.0047 15.9 22.6 0.011 14.7 22.6 1.5 1 0 0 1 1 1 1 Transcriptional activator LAG-3 CNDH2_C PF16858.5 RUS83919.1 - 0.0058 16.5 3.1 0.0058 16.5 3.1 4.8 3 1 2 5 5 5 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-H2C2_2 PF13465.6 RUS83919.1 - 0.01 16.3 0.0 0.01 16.3 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 RUS83919.1 - 0.022 15.2 4.4 0.022 15.2 4.4 6.9 7 0 0 7 7 7 0 Zinc finger, C2H2 type MCU PF04678.13 RUS83919.1 - 0.044 13.9 1.2 0.11 12.6 1.2 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PepSY_TM PF03929.16 RUS83919.1 - 0.6 9.7 1.8 1.9 8.1 1.8 1.8 1 0 0 1 1 1 0 PepSY-associated TM region zf-C2H2_4 PF13894.6 RUS83919.1 - 0.89 10.6 36.2 1.5 9.8 3.7 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger Kinesin_assoc PF16183.5 RUS83919.1 - 2.9 8.0 5.7 11 6.2 5.7 1.9 1 0 0 1 1 1 0 Kinesin-associated Selenoprotein_S PF06936.11 RUS83922.1 - 3.5e-31 108.5 3.5 3.9e-31 108.4 3.5 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) DUF4407 PF14362.6 RUS83922.1 - 0.019 14.3 1.4 0.022 14.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S49_N PF08496.10 RUS83922.1 - 0.03 14.4 0.9 0.038 14.1 0.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FliP PF00813.20 RUS83922.1 - 0.042 13.7 0.0 0.05 13.5 0.0 1.0 1 0 0 1 1 1 0 FliP family DUF1068 PF06364.12 RUS83922.1 - 0.23 11.3 4.3 0.31 10.9 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) MRI PF15325.6 RUS83923.1 - 0.045 14.8 4.7 0.045 14.8 4.7 2.5 2 1 0 2 2 2 0 Modulator of retrovirus infection Macoilin PF09726.9 RUS83923.1 - 0.14 10.7 15.8 0.21 10.1 15.8 1.2 1 0 0 1 1 1 0 Macoilin family OAF PF14941.6 RUS83924.1 - 2.1e-88 295.9 0.5 2.3e-88 295.8 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first BPD_transp_2 PF02653.16 RUS83925.1 - 0.021 14.0 8.2 0.024 13.8 8.2 1.0 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component SPT_ssu-like PF11779.8 RUS83925.1 - 0.29 10.8 0.2 0.29 10.8 0.2 2.7 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like DUF5305 PF17231.2 RUS83925.1 - 1.2 8.5 6.1 3.5 7.0 0.1 2.4 1 1 2 3 3 3 0 Family of unknown function (DUF5305) Wzy_C PF04932.15 RUS83925.1 - 4.4 6.9 7.2 1.8 8.2 4.1 1.8 1 1 1 2 2 2 0 O-Antigen ligase Lig_chan PF00060.26 RUS83925.1 - 4.7 7.0 4.7 11 5.8 0.1 2.6 1 1 1 2 2 2 0 Ligand-gated ion channel DUF4083 PF13314.6 RUS83925.1 - 9.4 6.3 10.5 6.5 6.8 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) Maelstrom PF13017.6 RUS83926.1 - 1.6e-37 129.3 0.1 2.2e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 RUS83926.1 - 2e-12 47.5 3.2 5.6e-12 46.1 3.2 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 RUS83926.1 - 4.4e-07 30.2 4.9 1.7e-06 28.3 4.6 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box PDEase_I PF00233.19 RUS83927.1 - 4.3e-67 226.3 5.8 3.2e-38 131.8 1.2 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RUS83927.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 HD domain SapB_1 PF05184.15 RUS83929.1 - 4e-08 33.1 0.9 4e-08 33.1 0.9 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 1 YopE PF03545.13 RUS83929.1 - 0.14 12.3 1.0 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) YmgB PF10798.8 RUS83929.1 - 3.8 7.4 6.5 1.1 9.1 2.8 2.0 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR Lectin_C PF00059.21 RUS83930.1 - 2.9e-10 40.8 26.4 3.6e-05 24.4 10.2 4.5 3 1 0 3 3 3 2 Lectin C-type domain DUF2457 PF10446.9 RUS83930.1 - 0.0025 17.1 27.9 0.0039 16.4 27.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS83930.1 - 0.046 11.8 26.7 0.06 11.4 26.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS83930.1 - 0.086 11.1 16.1 0.12 10.6 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS83930.1 - 0.17 10.1 12.2 0.25 9.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein WSC PF01822.19 RUS83930.1 - 0.26 11.5 11.1 3.4 7.9 3.3 3.4 3 0 0 3 3 3 0 WSC domain Sigma70_ner PF04546.13 RUS83930.1 - 0.29 11.0 12.0 0.46 10.3 12.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 RUS83930.1 - 1.1 8.6 15.9 1.5 8.2 15.9 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RUS83930.1 - 1.5 8.3 14.2 3.5 7.2 14.2 1.5 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 RUS83930.1 - 2.9 6.3 13.1 4.1 5.8 13.1 1.1 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 RUS83930.1 - 3.5 6.9 38.8 0.09 12.1 25.2 2.5 2 0 0 2 2 2 0 NOA36 protein BUD22 PF09073.10 RUS83930.1 - 8.9 5.5 14.4 13 5.0 14.4 1.1 1 0 0 1 1 1 0 BUD22 Orai-1 PF07856.12 RUS83931.1 - 3.3e-64 215.7 2.5 3.9e-64 215.5 2.5 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF2178 PF09946.9 RUS83931.1 - 1.1 9.5 10.7 2.4 8.4 1.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DUF3624 PF12292.8 RUS83931.1 - 2.6 8.5 6.6 3.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) DUF2207 PF09972.9 RUS83931.1 - 2.9 6.6 4.7 0.47 9.1 0.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) tRNA-synt_1b PF00579.25 RUS83934.1 - 2e-41 142.3 0.0 2.3e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PhoH PF02562.16 RUS83934.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 PhoH-like protein NAD_binding_7 PF13241.6 RUS83934.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-C2H2 PF00096.26 RUS83936.1 - 4.2e-22 77.3 36.0 4.7e-05 23.6 1.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS83936.1 - 3.4e-18 65.2 44.8 7.3e-06 26.2 0.8 6.8 7 1 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS83936.1 - 2.3e-12 46.6 32.5 0.01 16.6 0.8 6.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS83936.1 - 1.8e-10 41.0 16.1 0.00099 19.4 2.5 4.4 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RUS83936.1 - 0.0001 22.5 10.0 0.47 10.8 0.2 5.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.10 RUS83936.1 - 0.015 15.1 11.5 0.14 11.9 4.5 2.6 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 RUS83936.1 - 0.028 14.4 0.2 0.028 14.4 0.2 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger GbpC PF08363.10 RUS83936.1 - 0.071 12.6 1.9 0.093 12.2 0.3 1.9 2 0 0 2 2 2 0 Glucan-binding protein C zf_Hakai PF18408.1 RUS83936.1 - 1.5 8.6 11.3 6.4 6.6 0.3 4.3 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain CHORD PF04968.12 RUS83937.1 - 1.2e-43 147.6 12.8 3.8e-27 94.8 6.4 2.4 2 0 0 2 2 2 2 CHORD C5HCH PF17982.1 RUS83937.1 - 0.0044 17.1 1.3 3.6 7.8 0.1 2.5 2 0 0 2 2 2 2 NSD Cys-His rich domain Arm-DNA-bind_5 PF17293.2 RUS83937.1 - 0.077 13.5 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain BTK PF00779.19 RUS83937.1 - 8 6.4 20.5 7.6 6.4 5.0 3.4 3 2 0 3 3 3 0 BTK motif RNase_H PF00075.24 RUS83938.1 - 3.9e-07 30.3 1.7 9.8e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 RNase H DUF4864 PF16156.5 RUS83938.1 - 0.049 14.3 0.1 0.08 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) FIVAR PF07554.13 RUS83938.1 - 0.56 11.0 9.8 1.5 9.7 0.5 2.5 3 0 0 3 3 3 0 FIVAR domain Sec2p PF06428.11 RUS83938.1 - 0.83 9.7 4.5 0.3 11.1 0.6 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p rve PF00665.26 RUS83939.1 - 7.6e-15 55.2 0.0 1.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 RUS83939.1 - 1.1e-06 29.2 1.0 3.3e-06 27.7 0.3 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF1700 PF08006.11 RUS83940.1 - 8.1 5.9 10.1 20 4.6 10.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) LURAP PF14854.6 RUS83941.1 - 0.00085 19.3 7.3 0.13 12.2 2.7 2.4 1 1 1 2 2 2 2 Leucine rich adaptor protein Epiglycanin_TR PF05647.11 RUS83941.1 - 0.028 14.3 0.9 1.9 8.5 0.1 2.2 1 1 1 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Malic_M PF03949.15 RUS83941.1 - 0.24 10.6 0.9 2.2 7.5 0.9 2.0 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain BIRC6 PF12356.8 RUS83941.1 - 1.7 8.0 13.5 2.4 7.6 1.8 2.5 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 WD40 PF00400.32 RUS83944.1 - 2.4e-12 47.1 2.2 0.0055 17.5 0.3 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83944.1 - 7.6e-06 26.1 1.0 8.7e-05 22.7 1.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IR1-M PF12185.8 RUS83944.1 - 0.38 10.7 3.9 0.4 10.7 0.1 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF4604 PF15377.6 RUS83944.1 - 4.4 7.7 23.1 1.2 9.6 2.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) WD40 PF00400.32 RUS83945.1 - 2.9e-09 37.4 3.9 0.00095 19.9 0.3 6.5 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83945.1 - 0.008 16.5 0.0 6.7 7.1 0.0 3.5 1 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2 PF09337.10 RUS83946.1 - 5.7e-05 23.2 0.1 3e+02 1.7 0.0 6.5 7 0 0 7 7 7 0 H2C2 zinc finger DUF3106 PF11304.8 RUS83946.1 - 0.088 13.3 0.0 18 5.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF759 PF05537.11 RUS83946.1 - 0.42 9.4 5.4 36 3.1 0.1 3.4 1 1 6 7 7 7 0 Borrelia burgdorferi protein of unknown function (DUF759) Toxin_7 PF05980.12 RUS83947.1 - 0.00034 20.8 23.1 15 6.0 0.1 6.8 7 0 0 7 7 7 6 Toxin 7 BRCA-2_OB3 PF09104.10 RUS83947.1 - 0.0085 15.7 0.4 1.1 8.9 0.1 2.6 1 1 1 2 2 2 2 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Glyco_hydro_81 PF03639.13 RUS83947.1 - 0.078 12.1 0.1 40 3.2 0.0 2.9 1 1 3 4 4 4 0 Glycosyl hydrolase family 81 N-terminal domain ELK PF03789.13 RUS83947.1 - 1.1 9.4 5.6 3.8e+02 1.3 0.1 5.8 7 0 0 7 7 7 0 ELK domain N_Asn_amidohyd PF14736.6 RUS83947.1 - 6.4 5.9 10.0 1.7 7.7 1.7 2.3 1 1 2 3 3 3 0 Protein N-terminal asparagine amidohydrolase dDENN PF03455.19 RUS83948.1 - 2.6e-10 40.1 2.7 7.1 6.7 0.0 5.9 1 1 5 6 6 6 6 dDENN domain DicB PF05358.11 RUS83948.1 - 2.7e-10 40.3 1.1 3.3 7.9 0.0 5.8 1 1 5 6 6 6 5 DicB protein VitD-bind_III PF09164.10 RUS83948.1 - 0.00018 21.5 3.1 24 5.0 0.1 4.7 1 1 4 5 5 5 4 Vitamin D binding protein, domain III O_Spanin_T7 PF17531.2 RUS83948.1 - 1.8 8.7 10.9 1.7e+02 2.4 0.1 5.3 6 0 0 6 6 6 0 outer-membrane spanin sub-unit CENP-F_C_Rb_bdg PF10490.9 RUS83948.1 - 3.8 7.0 8.2 96 2.5 0.0 5.2 6 1 1 7 7 7 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 MGC-24 PF05283.11 RUS83949.1 - 1.3e-16 61.3 21.4 2.4e-15 57.2 21.2 2.2 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-C2H2_10 PF16588.5 RUS83949.1 - 0.014 15.2 1.0 5.1 6.9 0.2 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger Ost5 PF05251.12 RUS83950.1 - 0.03 14.6 1.9 0.35 11.2 0.1 3.0 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Shisa PF13908.6 RUS83950.1 - 0.049 13.9 0.4 0.049 13.9 0.4 2.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator FAM176 PF14851.6 RUS83950.1 - 0.061 13.0 0.1 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 FAM176 family FPN1 PF06963.12 RUS83950.1 - 0.15 10.6 2.2 0.25 9.9 2.2 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2207 PF09972.9 RUS83950.1 - 0.23 10.2 0.1 0.38 9.5 0.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNase_H PF00075.24 RUS83951.1 - 1.4e-11 44.8 2.4 2.6e-11 43.9 2.4 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS83951.1 - 0.018 14.9 2.0 0.022 14.6 0.5 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like Pga1 PF10333.9 RUS83951.1 - 0.03 14.2 0.4 0.046 13.6 0.4 1.2 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator HATPase_c_5 PF14501.6 RUS83951.1 - 0.056 13.4 4.4 0.21 11.5 4.4 1.9 1 1 0 1 1 1 0 GHKL domain EB PF01683.18 RUS83955.1 - 2.8e-26 91.5 104.9 5e-05 23.5 11.5 8.5 1 1 8 9 9 9 8 EB module Dickkopf_N PF04706.12 RUS83955.1 - 5.4e-07 30.0 84.4 0.0051 17.3 6.8 8.0 4 2 4 8 8 8 6 Dickkopf N-terminal cysteine-rich region EGF PF00008.27 RUS83955.1 - 0.0005 20.3 2.0 0.0005 20.3 2.0 10.7 7 2 1 9 9 9 3 EGF-like domain EGF_3 PF12947.7 RUS83955.1 - 0.012 15.8 1.7 0.012 15.8 1.7 10.1 9 1 0 9 9 9 0 EGF domain hEGF PF12661.7 RUS83955.1 - 0.074 13.7 0.4 0.074 13.7 0.4 13.1 12 2 0 12 12 12 0 Human growth factor-like EGF Phage_holin_3_6 PF07332.11 RUS83956.1 - 0.0088 16.1 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Syndecan PF01034.20 RUS83956.1 - 0.013 15.4 0.3 0.021 14.7 0.3 1.2 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 RUS83956.1 - 0.028 15.3 0.0 0.029 15.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1201 PF06716.11 RUS83956.1 - 0.045 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Myc_target_1 PF15179.6 RUS83956.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 PNTB_4TM PF12769.7 RUS83957.1 - 0.065 13.7 22.5 1.2e+02 3.3 0.0 9.9 10 2 2 12 12 12 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF5543 PF17697.1 RUS83958.1 - 0.0061 16.8 17.9 0.47 10.7 0.7 4.2 1 1 3 4 4 4 2 Family of unknown function (DUF5543) Nop14 PF04147.12 RUS83958.1 - 0.0096 14.2 19.6 0.013 13.8 19.6 1.2 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.12 RUS83958.1 - 0.011 15.2 14.1 0.017 14.6 14.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 RUS83958.1 - 0.021 14.6 10.8 0.041 13.6 10.8 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 RUS83958.1 - 0.026 12.8 16.5 0.033 12.5 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS83958.1 - 0.028 13.8 18.9 0.038 13.4 18.9 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS83958.1 - 0.11 10.5 36.6 0.15 10.2 36.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RUS83958.1 - 0.17 10.3 15.4 0.25 9.7 15.4 1.2 1 0 0 1 1 1 0 Mpp10 protein B12D PF06522.11 RUS83958.1 - 0.24 11.2 3.4 14 5.6 0.1 4.5 2 1 2 5 5 5 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Amelotin PF15757.5 RUS83958.1 - 0.7 9.4 6.0 2.8 7.5 0.7 2.7 1 1 1 2 2 2 0 Amelotin TRAP_alpha PF03896.16 RUS83958.1 - 7.3 5.7 14.1 1.9 7.6 11.1 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.13 RUS83958.1 - 8.1 6.3 20.8 16 5.3 20.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CRF-BP PF05428.11 RUS83959.1 - 6.1e-10 38.4 0.0 8.8e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) BES1_N PF05687.13 RUS83959.1 - 1.9 8.9 6.8 3.1 8.2 6.8 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF515 PF04415.12 RUS83959.1 - 5.3 5.3 6.8 7.4 4.8 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF5423 PF17461.2 RUS83959.1 - 8.8 5.1 17.9 15 4.4 17.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Lectin_leg-like PF03388.13 RUS83961.1 - 1.7e-56 191.2 0.1 5.7e-36 124.0 0.1 2.2 1 1 1 2 2 2 2 Legume-like lectin family Bact_lectin PF18483.1 RUS83961.1 - 0.00029 20.9 0.1 0.032 14.3 0.0 2.4 2 1 1 3 3 3 2 Bacterial lectin EMP24_GP25L PF01105.24 RUS83961.1 - 0.033 14.1 0.6 0.067 13.1 0.5 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3394 PF11874.8 RUS83961.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) V-SNARE PF05008.15 RUS83961.1 - 0.14 12.5 1.9 0.26 11.7 0.3 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Mucin2_WxxW PF13330.6 RUS83966.1 - 0.00063 20.5 0.0 0.045 14.6 0.0 2.3 1 1 1 2 2 2 2 Mucin-2 protein WxxW repeating region WD40 PF00400.32 RUS83967.1 - 5.8e-63 207.3 19.1 7.2e-09 36.1 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS83967.1 - 4.1e-20 71.9 0.2 0.0014 18.8 0.0 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS83967.1 - 1.4e-12 47.6 1.8 0.053 12.8 0.0 5.4 1 1 2 5 5 5 5 WD40-like domain eIF2A PF08662.11 RUS83967.1 - 2.1e-08 34.3 2.2 0.00096 19.1 0.1 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RUS83967.1 - 6.3e-07 28.7 4.3 1.4 7.8 0.0 4.9 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RUS83967.1 - 2.5e-05 23.1 4.4 1.8 7.1 0.0 5.3 1 1 5 6 6 6 2 Nucleoporin Nup120/160 CEP19 PF14933.6 RUS83967.1 - 5.6e-05 23.5 0.0 8.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein WD40_3 PF15911.5 RUS83967.1 - 0.0036 17.3 0.1 3.8 7.6 0.0 3.6 2 1 1 3 3 3 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 RUS83967.1 - 0.033 13.1 0.6 2 7.2 0.1 3.0 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RUS83967.1 - 0.11 10.8 0.1 5.4 5.2 0.0 2.7 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PIP49_C PF12260.8 RUS83968.1 - 1.8e-42 145.1 0.0 2.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 CCDC106 PF15794.5 RUS83969.1 - 0.061 13.0 8.0 0.12 12.1 8.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 RUS83969.1 - 0.38 10.3 26.9 0.12 11.9 20.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RUS83969.1 - 0.52 11.0 31.4 0.1 13.3 1.9 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein API5 PF05918.11 RUS83969.1 - 0.96 8.2 4.3 1.3 7.8 4.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Apt1 PF10351.9 RUS83969.1 - 1.6 7.5 7.7 0.049 12.5 2.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 RUS83969.1 - 6 5.3 11.7 10 4.6 11.7 1.3 1 0 0 1 1 1 0 Macoilin family Ferritin PF00210.24 RUS83970.1 - 1.2e-28 99.8 3.2 1.7e-28 99.3 3.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 RUS83970.1 - 2.8e-05 24.5 0.2 4.3e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 RUS83971.1 - 1.4e-07 31.6 1.8 1.5e-05 24.9 0.2 2.4 2 0 0 2 2 2 2 Ferritin-like domain TNFR_c6 PF00020.18 RUS83973.1 - 1.5e-06 28.5 31.9 0.00026 21.3 4.9 5.4 2 2 3 5 5 5 3 TNFR/NGFR cysteine-rich region cEGF PF12662.7 RUS83975.1 - 0.068 13.1 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like Tme5_EGF_like PF09064.10 RUS83975.1 - 0.34 10.9 6.4 0.78 9.7 6.4 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like ComS PF17584.2 RUS83976.1 - 0.18 11.3 0.1 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Bacillus competence protein S SfLAP PF11139.8 RUS83977.1 - 0.057 12.8 0.2 5.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein NACHT PF05729.12 RUS83978.1 - 1.6e-08 34.6 0.1 6e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 RUS83978.1 - 1.5e-06 28.7 0.1 1.4e-05 25.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS83978.1 - 0.0011 19.2 0.0 0.0058 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 RUS83978.1 - 0.031 13.6 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 RUS83978.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RUS83978.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 RUS83978.1 - 0.2 11.0 0.0 0.61 9.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Esterase PF00756.20 RUS83980.1 - 1e-45 156.4 0.0 1.3e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 RUS83980.1 - 0.0053 15.7 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 RUS83980.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 RUS83980.1 - 0.053 13.0 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 RUS83981.1 - 2.2e-17 63.5 0.0 2.5e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Neur_chan_LBD PF02931.23 RUS83982.1 - 4.2e-24 85.2 1.0 5e-24 85.0 1.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS83983.1 - 2.3e-07 31.1 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region LRR_8 PF13855.6 RUS83985.1 - 2.5e-37 126.4 53.6 4.7e-11 42.3 3.3 7.9 3 2 6 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 RUS83985.1 - 3.3e-27 94.1 29.7 2.1e-05 24.8 0.2 8.3 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) Roc PF08477.13 RUS83985.1 - 9.5e-14 51.6 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 RUS83985.1 - 8e-13 48.6 0.0 3.9e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 RUS83985.1 - 2.5e-10 40.2 0.0 4.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Ras family LRR_1 PF00560.33 RUS83985.1 - 5e-07 29.4 36.9 3.5 8.5 0.1 12.7 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_5 PF13306.6 RUS83985.1 - 1.2e-06 28.5 0.0 0.032 14.2 0.0 2.6 3 0 0 3 3 2 2 BspA type Leucine rich repeat region (6 copies) Gtr1_RagA PF04670.12 RUS83985.1 - 0.00019 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_9 PF14580.6 RUS83985.1 - 0.00023 20.7 9.4 0.0025 17.4 0.1 4.1 1 1 2 4 4 4 1 Leucine-rich repeat SRPRB PF09439.10 RUS83985.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS83985.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3557 PF12078.8 RUS83985.1 - 0.052 13.5 2.8 7 6.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3557) UBM PF14377.6 RUS83985.1 - 0.1 12.1 0.2 3.7 7.1 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin binding region Arf PF00025.21 RUS83985.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family NUDIX_5 PF16705.5 RUS83986.1 - 2.4e-29 102.3 0.0 5.7e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Ank_5 PF13857.6 RUS83986.1 - 2.8e-12 46.6 0.1 3.2e-08 33.7 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FERM_M PF00373.18 RUS83986.1 - 2.8e-12 47.1 0.1 6.5e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 FERM central domain Ank_2 PF12796.7 RUS83986.1 - 3.1e-12 46.9 0.0 2.6e-06 27.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS83986.1 - 4.4e-11 43.1 0.2 4.7e-10 39.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS83986.1 - 4.8e-10 39.4 0.1 0.0017 18.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RUS83986.1 - 5.6e-10 38.6 0.1 0.0034 17.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat I-set PF07679.16 RUS83987.1 - 3.1e-15 56.0 0.1 5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS83987.1 - 9e-09 35.8 0.4 2.9e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS83987.1 - 2.2e-08 34.2 0.1 3.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS83987.1 - 7.5e-08 32.6 0.1 1.3e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS83987.1 - 1.8e-05 24.8 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS83987.1 - 0.0067 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain CCDC24 PF15669.5 RUS83989.1 - 0.014 15.3 1.1 0.028 14.3 1.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NDUF_B8 PF05821.11 RUS83989.1 - 0.097 12.5 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) CD225 PF04505.12 RUS83990.1 - 2.1e-06 27.8 0.4 4.2e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 RUS83990.1 - 0.032 14.0 0.9 0.059 13.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF456 PF04306.13 RUS83990.1 - 0.042 14.1 0.6 0.062 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SMYLE_N PF18615.1 RUS83990.1 - 1.4 8.4 4.0 2 7.9 4.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hamartin PF04388.12 RUS83990.1 - 1.9 7.0 12.8 2.4 6.7 12.8 1.2 1 0 0 1 1 1 0 Hamartin protein Glyco_transf_10 PF00852.19 RUS83991.1 - 1.3e-46 158.6 0.7 2.1e-46 157.8 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS83991.1 - 9.7e-18 64.6 0.0 3.8e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal DnaB_bind PF10410.9 RUS83991.1 - 0.071 13.3 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Fumarate_red_D PF02313.17 RUS83991.1 - 0.12 12.5 0.2 0.31 11.2 0.2 1.7 1 0 0 1 1 1 0 Fumarate reductase subunit D HhH-GPD PF00730.25 RUS83991.1 - 0.15 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DNA_pol_viral_C PF00336.18 RUS83992.1 - 0.41 10.0 5.2 0.24 10.8 1.1 2.3 1 1 1 2 2 2 0 DNA polymerase (viral) C-terminal domain POLO_box PF00659.18 RUS83992.1 - 1.6 9.0 6.3 93 3.3 0.1 3.9 3 1 0 4 4 4 0 POLO box duplicated region DUF1382 PF07131.11 RUS83992.1 - 2.3 8.3 9.8 1.1e+02 2.9 0.0 5.8 3 3 3 6 6 6 0 Protein of unknown function (DUF1382) Pkinase_Tyr PF07714.17 RUS83994.1 - 2.9e-93 311.9 0.0 3.7e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS83994.1 - 1e-42 146.3 0.0 1.4e-41 142.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain ABC1 PF03109.16 RUS83994.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Rod_cone_degen PF15201.6 RUS83994.1 - 0.51 10.5 2.0 18 5.5 0.1 2.4 2 0 0 2 2 2 0 Progressive rod-cone degeneration Galactosyl_T PF01762.21 RUS83996.1 - 2.1e-05 24.5 0.0 7.2e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Galactosyltransferase Hydrolase_6 PF13344.6 RUS83996.1 - 0.0018 18.4 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Neur_chan_LBD PF02931.23 RUS83997.1 - 3.1e-08 33.3 0.7 5.8e-08 32.4 0.4 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS83997.1 - 5.1e-05 23.4 3.5 9.7e-05 22.5 3.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF5367 PF17329.2 RUS83997.1 - 0.09 12.9 3.8 0.044 13.9 1.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5367) AAA PF00004.29 RUS84000.1 - 5.4e-96 318.1 0.0 1.6e-46 158.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS84000.1 - 2e-26 91.5 6.0 2e-12 46.7 0.4 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 RUS84000.1 - 3.6e-22 78.4 0.4 1.8e-21 76.1 0.5 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 RUS84000.1 - 8.8e-14 51.5 0.0 1.8e-05 24.6 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RUS84000.1 - 1.1e-13 51.9 0.5 7.3e-05 23.2 0.1 4.6 3 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 RUS84000.1 - 3.5e-11 42.7 0.0 6.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 RUS84000.1 - 7.3e-11 42.4 0.0 3.4e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 RUS84000.1 - 1.1e-10 41.9 0.0 4.4e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RUS84000.1 - 1.5e-10 41.2 0.1 3.2e-05 24.0 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS84000.1 - 1.3e-09 38.4 0.2 0.013 15.8 0.2 4.0 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 RUS84000.1 - 8.2e-09 35.1 0.0 0.0011 18.2 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 RUS84000.1 - 5.2e-08 33.5 0.0 0.016 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 RUS84000.1 - 1.3e-07 31.5 0.2 8e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 RUS84000.1 - 2.3e-07 31.2 0.0 0.0057 17.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 RUS84000.1 - 2.9e-07 30.1 0.1 0.017 14.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RUS84000.1 - 6.2e-07 29.3 0.0 0.056 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 RUS84000.1 - 1.1e-06 28.7 0.0 0.052 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RUS84000.1 - 2.4e-06 27.2 0.0 0.066 12.7 0.0 3.4 3 1 0 3 3 3 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 RUS84000.1 - 2.9e-06 26.6 0.1 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 RUS84000.1 - 3.8e-06 27.2 0.0 0.18 12.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 RUS84000.1 - 4.7e-06 26.7 0.3 0.25 11.2 0.0 4.0 4 1 1 5 5 4 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RUS84000.1 - 1.3e-05 25.7 0.0 0.014 15.9 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 RUS84000.1 - 1.3e-05 25.1 0.0 0.082 12.7 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 RUS84000.1 - 1.5e-05 24.7 1.3 1.4 8.5 0.0 3.6 2 2 0 3 3 3 2 AAA domain AAA_24 PF13479.6 RUS84000.1 - 3e-05 23.8 0.1 0.085 12.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 RUS84000.1 - 3.8e-05 23.2 0.2 1.7 7.9 0.0 3.3 3 0 0 3 3 3 2 KaiC TsaE PF02367.17 RUS84000.1 - 4.8e-05 23.4 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RUS84000.1 - 5e-05 22.6 0.0 0.05 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 RUS84000.1 - 6.3e-05 23.4 0.0 0.99 9.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 RUS84000.1 - 8.6e-05 22.3 0.0 0.39 10.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 RUS84000.1 - 0.00014 21.7 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 RUS84000.1 - 0.00019 21.4 0.1 0.32 10.9 0.0 3.4 3 1 0 4 4 3 1 NACHT domain NB-ARC PF00931.22 RUS84000.1 - 0.00033 19.9 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 RUS84000.1 - 0.00044 20.3 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 RUS84000.1 - 0.00048 19.5 0.0 0.55 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 RUS84000.1 - 0.00076 18.8 0.0 0.35 10.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 RUS84000.1 - 0.00079 19.3 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 RUS84000.1 - 0.00093 19.3 0.0 2.5 8.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 RUS84000.1 - 0.001 18.6 0.3 1.5 8.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 RUS84000.1 - 0.0016 18.2 0.1 2.3 7.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RUS84000.1 - 0.004 17.1 0.0 0.79 9.6 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 RUS84000.1 - 0.0058 17.0 1.1 3.2 8.1 0.2 3.0 2 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 RUS84000.1 - 0.021 14.6 0.3 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RUS84000.1 - 0.029 14.3 0.2 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 RUS84000.1 - 0.039 13.7 0.1 9.5 5.9 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase SKI PF01202.22 RUS84000.1 - 0.042 14.0 0.2 8.1 6.5 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin2 PF13189.6 RUS84000.1 - 0.044 13.9 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family UFD1 PF03152.14 RUS84000.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 RUS84000.1 - 0.066 12.4 0.1 1.7 7.8 0.0 2.8 2 2 2 4 4 4 0 KAP family P-loop domain T2SSE PF00437.20 RUS84000.1 - 0.08 12.0 0.0 5.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.12 RUS84000.1 - 0.099 12.3 0.0 1.5 8.4 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TniB PF05621.11 RUS84000.1 - 0.13 11.7 0.0 12 5.3 0.0 2.9 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 RUS84000.1 - 0.17 11.7 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 RUS84000.1 - 0.33 11.4 1.7 14 6.1 0.2 3.0 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 RUS84001.1 - 4e-49 166.8 0.0 5.6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS84001.1 - 1.8e-29 102.3 0.0 4.6e-29 101.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RanBP PF00641.18 RUS84001.1 - 5.3e-16 57.6 29.0 7.5e-07 28.4 4.6 3.3 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others ResIII PF04851.15 RUS84001.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAD_binding_6 PF00970.24 RUS84002.1 - 6.4e-13 48.9 0.1 9.8e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Oxidored-like PF09791.9 RUS84002.1 - 2.1e-10 40.1 1.8 3.8e-10 39.3 1.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal RWD PF05773.22 RUS84002.1 - 0.06 13.6 0.5 0.11 12.8 0.5 1.7 1 1 0 1 1 1 0 RWD domain Iso_dh PF00180.20 RUS84003.1 - 1e-101 340.6 0.0 1.2e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 RUS84003.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA 7tm_2 PF00002.24 RUS84004.1 - 2e-10 40.4 13.7 3.8e-10 39.5 13.7 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Hus1 PF04005.12 RUS84004.1 - 0.063 12.4 0.0 7 5.7 0.0 2.2 2 0 0 2 2 2 0 Hus1-like protein UNC119_bdg PF15435.6 RUS84005.1 - 0.075 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue Apelin PF15360.6 RUS84006.1 - 0.047 14.3 2.7 72 4.0 0.1 4.5 1 1 5 6 6 6 0 APJ endogenous ligand PET117 PF15786.5 RUS84006.1 - 4.3 7.7 23.5 1.8e+04 -9.2 23.5 3.5 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial 7tm_1 PF00001.21 RUS84007.1 - 1.1e-17 64.3 3.7 1.1e-17 64.3 3.7 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84007.1 - 0.0013 18.2 5.8 0.0021 17.5 5.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FliS PF02561.14 RUS84008.1 - 0.028 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FliS DDE_Tnp_4 PF13359.6 RUS84009.1 - 1.9e-32 112.2 0.0 6.9e-31 107.1 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS84009.1 - 1.2e-07 31.6 0.1 8.2e-06 25.6 0.1 2.7 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS84009.1 - 5.7e-06 26.1 0.1 0.07 12.8 0.1 2.2 2 0 0 2 2 2 2 Transposase DDE domain HTH_Tnp_4 PF13613.6 RUS84009.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 RUS84009.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 RUS84009.1 - 0.085 12.8 0.2 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Crp PF00325.20 RUS84009.1 - 0.32 10.7 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family p53-inducible11 PF14936.6 RUS84010.1 - 1.3e-46 158.9 0.4 1.7e-46 158.5 0.4 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 RUS84010.1 - 0.14 12.1 3.2 0.14 12.0 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Abhydrolase_2 PF02230.16 RUS84011.1 - 5.8 6.7 5.0 16 5.2 5.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FARP PF01581.16 RUS84012.1 - 5.4e-10 38.0 94.1 1.1 10.0 0.5 16.9 17 1 1 18 18 18 14 FMRFamide related peptide family FARP PF01581.16 RUS84013.1 - 3.2e-05 23.6 59.0 0.15 12.7 2.0 7.7 7 0 0 7 7 7 6 FMRFamide related peptide family WW_like PF17890.1 RUS84015.1 - 0.92 9.6 15.2 2.7 8.2 0.9 3.6 2 1 2 4 4 4 0 Peptidoglycan hydrolase LytB WW-like domain DUF3270 PF11674.8 RUS84015.1 - 3.1 8.0 24.3 1.6 9.0 1.2 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3270) SET PF00856.28 RUS84016.1 - 3e-21 76.5 0.0 5.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 SET domain Tudor_4 PF18358.1 RUS84016.1 - 3.3e-17 61.8 0.1 6.3e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Pre-SET PF05033.16 RUS84016.1 - 2.7e-16 60.2 12.1 4.8e-16 59.4 11.1 2.0 2 0 0 2 2 2 1 Pre-SET motif MBD PF01429.19 RUS84016.1 - 2.2e-08 33.7 0.0 5.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain PapG_N PF03627.13 RUS84016.1 - 0.011 15.4 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 PapG carbohydrate binding domain fn3 PF00041.21 RUS84017.1 - 2.8e-40 136.5 2.6 7.7e-12 45.4 0.1 4.8 5 0 0 5 5 5 4 Fibronectin type III domain Kringle PF00051.18 RUS84017.1 - 2e-14 53.7 8.9 2e-14 53.7 8.9 2.3 2 0 0 2 2 2 1 Kringle domain Pur_ac_phosph_N PF16656.5 RUS84017.1 - 1.4e-08 35.2 0.5 0.02 15.4 0.0 4.4 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS84017.1 - 6.8e-06 26.4 0.1 0.015 15.6 0.1 3.7 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III PDEase_I PF00233.19 RUS84018.1 - 1.6e-63 214.7 0.4 2.9e-59 200.7 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase R3H-assoc PF13902.6 RUS84018.1 - 0.22 11.9 1.7 0.67 10.3 1.6 1.9 1 1 0 1 1 1 0 R3H-associated N-terminal domain DUF3275 PF11679.8 RUS84018.1 - 2 8.4 5.9 4.5 7.2 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DED PF01335.21 RUS84020.1 - 2.2e-15 56.7 3.2 4.6e-15 55.7 1.6 2.2 2 0 0 2 2 2 1 Death effector domain Nucleic_acid_bd PF13820.6 RUS84020.1 - 0.0024 17.7 0.1 0.004 17.0 0.1 1.4 1 0 0 1 1 1 1 Putative nucleic acid-binding region YBD PF17725.1 RUS84021.1 - 6.7e-97 323.4 0.7 8.9e-97 322.9 0.7 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 RUS84021.1 - 2.4e-27 94.8 0.0 5e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain CH PF00307.31 RUS84022.1 - 1.8e-27 95.7 0.8 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS84022.1 - 0.00088 19.1 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain TspO_MBR PF03073.15 RUS84023.1 - 4.7e-49 165.9 8.5 5.3e-49 165.7 8.5 1.0 1 0 0 1 1 1 1 TspO/MBR family TspO_MBR PF03073.15 RUS84024.1 - 5e-51 172.3 10.5 5.6e-51 172.1 10.5 1.0 1 0 0 1 1 1 1 TspO/MBR family TspO_MBR PF03073.15 RUS84025.1 - 2.7e-18 66.3 0.2 2.8e-18 66.3 0.2 1.0 1 0 0 1 1 1 1 TspO/MBR family RNase_H PF00075.24 RUS84026.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Bac_chlorC PF02043.17 RUS84027.1 - 0.75 9.8 6.6 57 3.8 0.0 4.2 4 0 0 4 4 4 0 Bacteriochlorophyll C binding protein Arrestin_N PF00339.29 RUS84028.1 - 1.1e-23 83.9 0.0 1.8e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS84028.1 - 4.7e-12 46.5 0.0 2.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RUS84028.1 - 0.00027 20.2 1.9 0.0011 18.2 0.3 2.0 2 0 0 2 2 2 1 Rgp1 Vps26 PF03643.15 RUS84028.1 - 0.00027 20.0 0.0 0.00032 19.8 0.0 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 SnAC PF14619.6 RUS84029.1 - 3e-05 24.5 0.1 14 6.3 0.0 4.0 4 0 0 4 4 4 3 Snf2-ATP coupling, chromatin remodelling complex Neurexophilin PF06312.12 RUS84029.1 - 0.004 16.7 0.0 17 4.8 0.0 3.8 1 1 3 4 4 4 1 Neurexophilin DUF4787 PF16029.5 RUS84030.1 - 2.9e-05 24.1 26.2 20 5.3 0.1 8.0 2 2 6 8 8 8 7 Domain of unknown function (DUF4787) DUF4077 PF13295.6 RUS84030.1 - 0.028 14.4 29.1 5.5 6.9 7.1 4.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4077) QVR PF17064.5 RUS84030.1 - 0.2 11.9 8.8 9.3 6.6 0.1 3.6 3 1 0 3 3 3 0 Sleepless protein 7TM_GPCR_Srt PF10321.9 RUS84030.1 - 0.21 10.6 22.6 1 8.3 3.6 3.0 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF5592 PF17332.2 RUS84030.1 - 4.1 8.0 11.2 77 3.9 0.1 4.2 1 1 1 3 3 3 0 Family of unknown function (DUF5592) DUF3915 PF13054.6 RUS84031.1 - 0.00038 20.4 3.8 0.00038 20.4 3.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) Phage_Gp23 PF10669.9 RUS84031.1 - 0.00048 20.5 1.1 0.00055 20.2 1.1 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Atrophin-1 PF03154.15 RUS84031.1 - 0.016 13.5 12.3 0.021 13.2 12.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family BAF250_C PF12031.8 RUS84031.1 - 0.039 13.2 0.1 0.046 13.0 0.1 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa FAM27 PF15832.5 RUS84031.1 - 0.31 11.6 5.8 0.41 11.2 5.8 1.3 1 0 0 1 1 1 0 FAM27 D and E protein family DUF3824 PF12868.7 RUS84031.1 - 4.2 8.0 6.0 5.5 7.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SSF PF00474.17 RUS84032.1 - 3.3e-42 144.8 19.8 4.5e-42 144.3 19.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family UCH PF00443.29 RUS84034.1 - 3.1e-50 171.1 0.6 5.9e-50 170.2 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS84034.1 - 3.3e-38 132.1 0.5 7.5e-38 130.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 RUS84034.1 - 5.1e-07 30.1 0.0 0.89 10.1 0.0 3.7 3 0 0 3 3 3 3 Ubiquitin-like domain ubiquitin PF00240.23 RUS84034.1 - 0.0034 17.1 0.3 7.9 6.3 0.0 3.9 3 0 0 3 3 3 1 Ubiquitin family Ubiquitin_3 PF14836.6 RUS84034.1 - 0.017 15.1 0.0 0.052 13.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain CAP_N PF01213.19 RUS84034.1 - 2.5 7.5 5.5 7.9 5.9 3.8 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RUS84034.1 - 10 6.2 9.4 4.2 7.4 5.6 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EBP PF05241.12 RUS84035.1 - 0.19 11.1 13.5 3.6 7.0 13.5 2.1 1 1 0 1 1 1 0 Emopamil binding protein BBS2_Mid PF14783.6 RUS84037.1 - 0.0036 17.3 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 RUS84037.1 - 0.015 14.1 1.5 0.065 12.0 0.1 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF1512 PF07431.12 RUS84037.1 - 0.052 12.5 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) VCBS PF13517.6 RUS84037.1 - 0.13 12.9 1.0 0.77 10.4 0.1 2.3 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AKAP7_NLS PF10469.9 RUS84038.1 - 2.3e-30 106.0 0.1 2.6e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 RUS84038.1 - 4.3e-11 42.9 0.0 5.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 RUS84038.1 - 3.7e-05 23.8 0.1 0.069 13.4 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase HsbA PF12296.8 RUS84038.1 - 0.095 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Tmemb_185A PF10269.9 RUS84041.1 - 2.5e-09 37.2 1.8 2.5e-09 37.2 1.8 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF2157 PF09925.9 RUS84041.1 - 0.13 12.0 2.5 0.19 11.5 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PrmA PF06325.13 RUS84042.1 - 0.00047 19.6 0.2 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RUS84042.1 - 0.00076 20.1 0.0 0.0027 18.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 RUS84042.1 - 0.0056 16.6 0.1 3.6 7.4 0.2 2.5 2 0 0 2 2 2 2 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 RUS84042.1 - 0.0061 16.6 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS84042.1 - 0.0081 15.7 0.2 0.046 13.3 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RUS84042.1 - 0.0085 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 RUS84042.1 - 0.011 15.3 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 RUS84042.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 RUS84042.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RUS84042.1 - 0.023 15.4 0.0 0.067 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RUS84042.1 - 0.082 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cu2_monoox_C PF03712.15 RUS84042.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Solute_trans_a PF03619.16 RUS84043.1 - 7.4e-85 284.7 13.1 1.2e-84 284.0 13.1 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha I-set PF07679.16 RUS84044.1 - 1.8e-13 50.3 0.0 2.2e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS84044.1 - 1.1e-10 42.0 0.2 2e-06 28.3 0.1 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS84044.1 - 1.3e-07 31.9 0.6 4.3e-07 30.2 0.3 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 RUS84044.1 - 0.003 17.7 1.0 0.0075 16.4 1.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain DUF1180 PF06679.12 RUS84044.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4064 PF13273.6 RUS84044.1 - 0.018 15.3 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4493 PF14900.6 RUS84044.1 - 0.057 13.3 0.7 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4493) TMEM154 PF15102.6 RUS84044.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 RUS84044.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF4538 PF15061.6 RUS84044.1 - 0.33 10.7 3.3 0.14 11.9 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Sigma_reg_N PF13800.6 RUS84044.1 - 0.65 10.3 2.2 0.79 10.0 0.8 1.8 1 1 1 2 2 2 0 Sigma factor regulator N-terminal MBG_2 PF18676.1 RUS84044.1 - 2 9.1 6.1 1.3 9.7 0.6 2.6 2 1 0 2 2 2 0 MBG domain (YGX type) NHL PF01436.21 RUS84045.1 - 2.3e-12 46.3 3.3 0.00014 21.8 0.1 3.9 3 0 0 3 3 3 3 NHL repeat DUF3583 PF12126.8 RUS84045.1 - 4.3e-08 33.0 1.1 8.9e-08 32.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) zf-B_box PF00643.24 RUS84045.1 - 2.8e-06 27.4 7.8 2.8e-06 27.4 7.8 3.9 5 0 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS84045.1 - 9.5e-05 22.3 7.0 9.5e-05 22.3 7.0 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS84045.1 - 0.0023 17.8 10.8 0.0023 17.8 10.8 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 RUS84045.1 - 0.0053 16.7 0.4 0.008 16.1 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain zf-RING_5 PF14634.6 RUS84045.1 - 0.012 15.5 8.2 0.012 15.5 8.2 4.7 4 1 0 4 4 4 0 zinc-RING finger domain SGL PF08450.12 RUS84045.1 - 0.015 14.9 0.8 1.1 8.8 0.0 2.7 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF3422 PF11902.8 RUS84045.1 - 0.038 13.1 1.5 0.06 12.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF883 PF05957.13 RUS84045.1 - 0.068 13.8 1.1 0.17 12.5 1.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.6 RUS84046.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF3024 PF11225.8 RUS84047.1 - 9e-09 35.5 53.7 2.8 8.3 0.3 11.2 1 1 13 14 14 14 14 Protein of unknown function (DUF3024) HicB-like_2 PF15970.5 RUS84048.1 - 3.2e-10 40.0 6.6 19 5.5 0.0 9.1 1 1 11 12 12 12 11 HicB_like antitoxin of bacterial toxin-antitoxin system Phospho_p8 PF10195.9 RUS84049.1 - 8.4e-20 71.0 3.1 9.6e-20 70.8 3.1 1.1 1 0 0 1 1 1 1 DNA-binding nuclear phosphoprotein p8 MARVEL PF01284.23 RUS84051.1 - 1.8e-32 112.4 7.4 2.3e-32 112.0 7.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4227 PF14004.6 RUS84052.1 - 0.26 11.3 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Proteasome PF00227.26 RUS84053.1 - 5.5e-58 195.6 0.1 7e-58 195.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS84053.1 - 6.8e-14 51.2 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CtIP_N PF10482.9 RUS84053.1 - 0.065 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Antimicrobial22 PF16047.5 RUS84053.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide Globin PF00042.22 RUS84055.1 - 6.2e-09 36.4 0.0 1.5e-08 35.2 0.0 1.5 1 1 1 2 2 2 1 Globin Globin PF00042.22 RUS84056.1 - 2e-11 44.4 0.2 7.5e-11 42.6 0.0 1.8 1 1 1 2 2 2 1 Globin GSAP-16 PF14959.6 RUS84057.1 - 3.1e-29 101.0 0.1 1e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term LPD25 PF18840.1 RUS84058.1 - 0.12 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 Hist_deacetyl PF00850.19 RUS84060.1 - 8.4e-82 275.1 0.1 2.8e-77 260.2 0.0 2.7 2 1 0 2 2 2 2 Histone deacetylase domain DUF1160 PF06648.11 RUS84061.1 - 0.0021 18.0 1.3 0.0032 17.5 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1160) Glyco_hydro81C PF17652.1 RUS84061.1 - 0.0047 16.2 0.5 0.0051 16.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain RNR_N PF08343.10 RUS84061.1 - 0.024 14.6 2.9 0.051 13.6 2.9 1.7 1 1 0 1 1 1 0 Ribonucleotide reductase N-terminal SID-1_RNA_chan PF13965.6 RUS84062.1 - 2 6.7 8.9 2.1 6.7 8.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-C2H2 PF00096.26 RUS84064.1 - 2.5e-05 24.5 14.5 0.017 15.6 0.1 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 RUS84064.1 - 4.6e-05 23.6 10.3 0.0063 16.9 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS84064.1 - 0.00014 22.4 15.7 0.094 13.6 0.1 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS84064.1 - 0.007 16.6 2.9 17 5.9 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS84064.1 - 0.42 11.0 7.6 1.2 9.5 0.0 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 RUS84064.1 - 0.65 9.9 3.9 22 5.0 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING_UBOX PF13445.6 RUS84065.1 - 9e-06 25.6 4.5 1.8e-05 24.7 4.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS84065.1 - 2.5e-05 24.1 4.2 4.6e-05 23.2 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS84065.1 - 0.00035 20.7 4.4 0.00065 19.8 4.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 RUS84065.1 - 0.00056 19.7 6.8 0.00056 19.7 6.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS84065.1 - 0.0057 17.0 7.7 0.012 15.9 7.7 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS84065.1 - 0.012 15.5 7.3 0.023 14.6 7.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS84065.1 - 0.016 15.1 3.9 0.016 15.1 3.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS84065.1 - 0.036 13.9 4.2 0.036 13.9 4.2 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 RUS84065.1 - 0.41 10.9 4.8 5.7 7.2 2.8 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 RUS84065.1 - 3.9 7.3 6.6 9 6.1 6.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger p450 PF00067.22 RUS84066.1 - 5.3e-92 309.0 0.0 6e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.11 RUS84066.1 - 0.66 10.1 4.4 8.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) 7TM_GPCR_Srw PF10324.9 RUS84067.1 - 8.5e-06 25.3 2.0 1.2e-05 24.8 2.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Cyclin_N PF00134.23 RUS84069.1 - 1.8e-16 60.0 2.4 2.6e-15 56.3 0.2 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain DNA_pol_phi PF04931.13 RUS84070.1 - 0.00038 18.7 20.7 0.00044 18.5 20.7 1.0 1 0 0 1 1 1 1 DNA polymerase phi TFIIA PF03153.13 RUS84070.1 - 0.27 11.2 21.4 0.32 11.0 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 RUS84070.1 - 1.9 8.3 12.5 3.1 7.6 12.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 RUS84070.1 - 3.4 6.8 6.7 4.7 6.3 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 RUS84070.1 - 9.4 4.6 15.8 12 4.3 15.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hormone_recep PF00104.30 RUS84072.1 - 1.9e-13 50.5 0.0 6e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tautomerase PF01361.21 RUS84072.1 - 0.16 11.9 0.2 0.37 10.7 0.2 1.6 1 0 0 1 1 1 0 Tautomerase enzyme GTA_TIM PF13547.6 RUS84073.1 - 0.31 10.3 0.9 0.63 9.3 1.0 1.4 1 1 1 2 2 2 0 GTA TIM-barrel-like domain TFIIA PF03153.13 RUS84073.1 - 1.2 9.0 7.8 1.5 8.7 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VID27_N PF17748.1 RUS84074.1 - 0.031 14.1 4.6 0.05 13.5 4.6 1.2 1 0 0 1 1 1 0 VID27 N-terminal region DUF3165 PF11364.8 RUS84074.1 - 0.038 14.3 18.9 13 6.2 0.7 5.5 1 1 6 7 7 7 0 Protein of unknown function (DUF3165) E7 PF00527.18 RUS84074.1 - 0.07 13.3 1.7 0.13 12.5 1.7 1.4 1 0 0 1 1 1 0 E7 protein, Early protein FAM176 PF14851.6 RUS84074.1 - 0.15 11.7 4.0 0.25 11.0 4.0 1.3 1 0 0 1 1 1 0 FAM176 family PAC1 PF16094.5 RUS84074.1 - 0.36 10.0 1.4 0.61 9.2 1.4 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 PI3K_1B_p101 PF10486.9 RUS84074.1 - 0.58 7.9 0.9 0.72 7.6 0.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Radial_spoke PF04712.12 RUS84074.1 - 2.1 7.2 13.4 2.7 6.8 13.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4746 PF15928.5 RUS84074.1 - 2.3 7.6 9.7 3.2 7.1 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-B_dimeris PF09026.10 RUS84074.1 - 8.5 6.8 10.3 23 5.5 10.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RPN2_C PF18004.1 RUS84074.1 - 9.1 6.2 8.5 14 5.6 8.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Peptidase_M1_N PF17900.1 RUS84075.1 - 0.0025 18.0 3.1 12 6.0 0.2 3.7 1 1 5 6 6 6 3 Peptidase M1 N-terminal domain JHBP PF06585.11 RUS84075.1 - 0.0094 15.1 0.6 0.5 9.5 0.1 2.1 1 1 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) PAN_4 PF14295.6 RUS84075.1 - 0.06 13.3 20.2 39 4.2 1.6 6.0 1 1 2 3 3 3 0 PAN domain DUF722 PF05263.11 RUS84075.1 - 0.086 13.1 1.3 42 4.4 0.0 3.2 1 1 4 5 5 5 0 Protein of unknown function (DUF722) ShK PF01549.24 RUS84075.1 - 0.14 12.7 7.7 44 4.7 0.4 4.9 1 1 2 3 3 3 0 ShK domain-like ISG65-75 PF11727.8 RUS84075.1 - 3 7.0 9.4 4.5 6.4 1.7 2.7 1 1 2 3 3 3 0 Invariant surface glycoprotein SH2 PF00017.24 RUS84076.1 - 1.3e-07 31.6 0.1 2.7e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 RUS84076.1 - 6.9e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Copine PF07002.16 RUS84077.1 - 1.1e-86 289.8 0.0 1.5e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS84077.1 - 1.2e-28 99.4 0.0 9e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 RUS84077.1 - 0.00014 22.0 0.0 0.0006 20.0 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus MoCF_biosynth PF00994.24 RUS84078.1 - 0.17 11.5 2.4 42 3.8 0.1 3.9 1 1 1 2 2 2 0 Probable molybdopterin binding domain HlyIII PF03006.20 RUS84079.1 - 2e-72 243.6 22.4 2.4e-72 243.3 22.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related CopD PF05425.13 RUS84079.1 - 0.02 15.3 1.2 0.02 15.3 1.2 2.6 3 0 0 3 3 3 0 Copper resistance protein D NADH-u_ox-rdase PF10785.9 RUS84079.1 - 0.13 13.0 0.2 0.48 11.2 0.0 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Usp PF00582.26 RUS84080.1 - 6.1e-21 75.4 0.0 2.4e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family DAGK_cat PF00781.24 RUS84080.1 - 0.0054 16.3 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1611 PF07755.11 RUS84080.1 - 0.069 12.4 1.1 0.11 11.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain DUF4481 PF14800.6 RUS84080.1 - 0.076 12.5 0.2 0.087 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF333 PF03891.15 RUS84082.1 - 6.3e-08 32.7 16.8 0.029 14.6 0.2 5.8 1 1 7 8 8 8 8 Domain of unknown function (DUF333) Pentapeptide_4 PF13599.6 RUS84082.1 - 3.9e-06 26.9 0.0 0.098 12.8 0.0 2.7 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) MCPVI PF02993.14 RUS84082.1 - 0.28 11.0 8.7 17 5.2 0.2 4.3 1 1 2 3 3 3 0 Minor capsid protein VI zf-C4_Topoisom PF01396.19 RUS84082.1 - 0.3 10.9 6.1 29 4.5 0.1 4.0 4 1 1 5 5 5 0 Topoisomerase DNA binding C4 zinc finger JmjC PF02373.22 RUS84083.1 - 3e-12 47.0 0.0 1e-11 45.2 0.0 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 RUS84083.1 - 0.0016 18.8 3.8 0.005 17.2 3.8 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger Cupin_2 PF07883.11 RUS84083.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain C1_2 PF03107.16 RUS84083.1 - 0.12 12.7 7.0 0.45 10.9 7.0 2.0 1 0 0 1 1 1 0 C1 domain Zn_ribbon_17 PF17120.5 RUS84083.1 - 0.26 10.9 5.2 0.65 9.7 5.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UBP PF02148.19 RUS84083.1 - 1 9.8 6.2 3.1 8.2 6.2 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4_3 PF13920.6 RUS84083.1 - 1 9.3 5.5 2.5 8.0 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Transcrip_reg PF01709.20 RUS84084.1 - 1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator PWWP PF00855.17 RUS84085.1 - 2.3e-13 50.3 0.2 2.3e-13 50.3 0.2 2.7 2 0 0 2 2 2 1 PWWP domain MFS_1 PF07690.16 RUS84086.1 - 1.1e-22 80.5 35.3 5.4e-22 78.2 35.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sulfotransfer_1 PF00685.27 RUS84087.1 - 8.2e-21 74.7 0.0 6.3e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS84087.1 - 6e-12 46.4 0.0 4.1e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 RUS84088.1 - 1.5e-17 63.5 24.1 1.3e-09 37.5 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 RUS84088.1 - 0.16 10.7 0.0 0.45 9.2 0.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Lectin_C PF00059.21 RUS84090.1 - 3.7e-15 56.6 0.0 6.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain V-set PF07686.17 RUS84090.1 - 0.0072 16.5 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Lectin_C PF00059.21 RUS84091.1 - 3.3e-18 66.4 1.5 3.3e-18 66.4 1.5 1.6 2 0 0 2 2 2 1 Lectin C-type domain UnbV_ASPIC PF07593.12 RUS84091.1 - 0.13 12.2 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 ASPIC and UnbV LIDHydrolase PF10230.9 RUS84092.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Na_Ca_ex PF01699.24 RUS84093.1 - 4.6e-46 156.5 51.2 6.1e-23 81.4 23.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BCOR PF15808.5 RUS84094.1 - 0.0022 18.3 0.1 0.0051 17.1 0.1 1.6 1 0 0 1 1 1 1 BCL-6 co-repressor, non-ankyrin-repeat region REV PF00424.18 RUS84094.1 - 0.047 13.7 0.2 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) UBA2_C PF16195.5 RUS84094.1 - 0.057 14.1 0.5 6.4 7.5 0.0 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus CH_2 PF06294.11 RUS84095.1 - 2.3e-31 107.8 0.2 5.6e-31 106.5 0.0 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RUS84095.1 - 4.2e-14 52.2 0.1 1.1e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 RUS84095.1 - 0.0086 16.2 0.3 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain PKcGMP_CC PF16808.5 RUS84095.1 - 0.022 14.6 0.3 0.022 14.6 0.3 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PT PF04886.12 RUS84096.1 - 9.7e-06 25.0 10.4 0.002 17.6 2.5 4.5 1 1 1 2 2 2 2 PT repeat Bromodomain PF00439.25 RUS84096.1 - 7.1 6.8 21.8 1.8e+04 -13.2 21.8 5.9 1 1 0 1 1 1 0 Bromodomain zf-H2C2_5 PF13909.6 RUS84097.1 - 0.68 9.7 14.6 0.24 11.2 5.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS84097.1 - 1.3 10.0 11.2 2.5 9.2 1.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS84097.1 - 2 9.0 14.2 0.38 11.3 3.0 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.6 RUS84098.1 - 8.4e-07 28.9 4.9 8.4e-07 28.9 4.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS84098.1 - 8.9e-06 25.4 2.3 8.9e-06 25.4 2.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS84098.1 - 4.9e-05 23.1 3.5 4.9e-05 23.1 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS84098.1 - 0.00011 22.0 3.9 0.00011 22.0 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS84098.1 - 0.00012 22.1 3.7 0.00012 22.1 3.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS84098.1 - 0.00014 21.6 3.9 0.00037 20.3 3.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS84098.1 - 0.0028 17.6 4.3 0.0028 17.6 4.3 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS84098.1 - 0.01 16.2 4.7 0.01 16.2 4.7 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.6 RUS84098.1 - 0.55 10.1 7.2 0.039 13.8 1.9 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 RUS84098.1 - 2.5 7.9 5.6 4.9 7.0 4.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger UDG PF03167.19 RUS84099.1 - 4e-22 78.9 0.2 1e-21 77.5 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily HSNSD PF12062.8 RUS84100.1 - 4.8e-96 322.4 0.0 8.1e-96 321.7 0.0 1.4 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 RUS84100.1 - 1.1e-20 74.2 0.2 1.6e-20 73.7 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS84100.1 - 3.2e-10 40.7 0.2 8.5e-10 39.4 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family TauD PF02668.16 RUS84101.1 - 9.1e-27 94.5 0.2 1.3e-26 94.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Iso_dh PF00180.20 RUS84103.1 - 9.2e-63 212.5 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4558 PF15104.6 RUS84103.1 - 0.15 12.2 0.6 0.3 11.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) His_Phos_1 PF00300.22 RUS84104.1 - 9.9e-21 74.3 0.0 1.8e-14 53.9 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) BpuSI_N PF15516.6 RUS84104.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 BpuSI N-terminal domain FERM_C PF09380.10 RUS84105.1 - 3.7e-19 68.9 0.2 6.5e-19 68.1 0.2 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS84105.1 - 4.1e-19 69.1 0.0 7.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS84105.1 - 9.2e-17 60.8 0.1 3.8e-16 58.8 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain DUF1656 PF07869.12 RUS84107.1 - 0.4 10.7 5.1 0.58 10.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) FA_desaturase PF00487.24 RUS84109.1 - 5.3e-16 59.2 14.5 5.3e-16 59.2 14.5 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Ig_3 PF13927.6 RUS84110.1 - 6.8e-10 39.4 0.2 3.3e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS84110.1 - 1.5e-09 37.9 1.5 2e-07 31.1 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS84110.1 - 3.3e-08 33.7 0.1 0.0018 18.6 0.0 2.9 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS84110.1 - 3.6e-08 33.6 0.2 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 RUS84110.1 - 3.7e-08 33.3 0.1 1.2e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain Receptor_2B4 PF11465.8 RUS84110.1 - 0.0042 17.3 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 Cornifin PF02389.15 RUS84112.1 - 8.9e-10 38.9 17.9 2.2e-05 24.7 7.2 2.0 1 1 1 2 2 2 2 Cornifin (SPRR) family GST_N_5 PF18485.1 RUS84112.1 - 0.0039 17.5 12.1 26 5.2 1.2 5.7 1 1 3 4 4 4 4 Glutathione S-transferase, N-terminal domain BPS PF08947.10 RUS84113.1 - 0.031 14.1 7.5 11 5.9 0.1 3.7 1 1 3 4 4 4 0 BPS (Between PH and SH2) DUF1199 PF06712.11 RUS84113.1 - 0.54 10.3 7.0 47 4.1 0.2 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1199) DUF406 PF04175.12 RUS84113.1 - 1.1 9.8 11.5 31 5.1 0.1 4.8 1 1 2 3 3 3 0 Protein of unknown function (DUF406) YL1 PF05764.13 RUS84114.1 - 6.4e-05 23.2 15.1 7.9e-05 22.9 15.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein AF-4 PF05110.13 RUS84114.1 - 0.0023 16.1 12.4 0.0023 16.1 12.4 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Rtf2 PF04641.12 RUS84114.1 - 0.0086 15.5 16.7 0.013 14.9 16.7 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Eapp_C PF10238.9 RUS84114.1 - 0.017 15.2 7.5 0.025 14.6 7.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein VSG_B PF13206.6 RUS84114.1 - 0.04 13.2 13.5 0.055 12.7 13.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Connexin PF00029.19 RUS84114.1 - 0.044 13.5 12.3 0.058 13.1 12.3 1.1 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 RUS84114.1 - 0.044 11.9 16.9 0.056 11.5 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SpoIIP PF07454.11 RUS84114.1 - 0.046 13.2 9.3 0.056 12.9 9.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 RUS84114.1 - 0.079 13.3 22.8 0.14 12.5 22.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BRF1 PF07741.13 RUS84114.1 - 0.09 13.1 22.6 0.18 12.2 22.6 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Presenilin PF01080.17 RUS84114.1 - 0.13 11.0 6.0 0.15 10.8 6.0 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_U57 PF05582.12 RUS84114.1 - 0.16 11.2 10.4 0.26 10.5 10.4 1.3 1 0 0 1 1 1 0 YabG peptidase U57 OATP PF03137.20 RUS84114.1 - 0.16 10.2 5.2 0.19 10.0 5.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LicD PF04991.13 RUS84114.1 - 0.16 12.1 11.8 0.22 11.6 11.8 1.1 1 0 0 1 1 1 0 LicD family DUF1764 PF08576.10 RUS84114.1 - 0.17 12.8 20.7 0.28 12.1 20.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4228 PF14009.6 RUS84114.1 - 0.18 12.2 5.5 0.22 11.9 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RPN2_C PF18004.1 RUS84114.1 - 0.18 11.7 21.2 0.25 11.3 21.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Rxt3 PF08642.10 RUS84114.1 - 0.24 12.2 4.4 0.38 11.5 4.4 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PPL5 PF18168.1 RUS84114.1 - 0.29 10.4 11.6 0.41 9.9 11.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Ctr PF04145.15 RUS84114.1 - 0.36 11.4 2.5 0.57 10.8 2.5 1.3 1 0 0 1 1 1 0 Ctr copper transporter family CDC45 PF02724.14 RUS84114.1 - 0.38 9.0 12.2 0.49 8.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_11 PF13086.6 RUS84114.1 - 0.42 10.3 11.5 0.57 9.9 11.5 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 RUS84114.1 - 0.43 10.4 16.7 0.59 9.9 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 RUS84114.1 - 0.46 10.8 21.4 0.63 10.3 21.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) ORC_WH_C PF18137.1 RUS84114.1 - 0.46 10.5 11.5 0.74 9.9 11.5 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Kei1 PF08552.11 RUS84114.1 - 0.48 10.3 2.2 0.89 9.4 1.8 1.5 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 Neur_chan_memb PF02932.16 RUS84114.1 - 0.53 10.3 3.5 0.63 10.1 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Afi1 PF07792.12 RUS84114.1 - 0.59 10.6 9.2 0.97 9.9 9.2 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FHIPEP PF00771.20 RUS84114.1 - 0.69 8.3 2.5 0.8 8.1 2.5 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3438 PF11920.8 RUS84114.1 - 0.73 9.0 7.0 1.1 8.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Zip PF02535.22 RUS84114.1 - 0.77 8.9 4.1 0.97 8.6 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 RUS84114.1 - 0.86 9.8 12.8 0.37 11.0 10.1 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GAGA_bind PF06217.12 RUS84114.1 - 0.87 9.8 18.2 1.2 9.4 18.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family EIIBC-GUT_N PF03612.14 RUS84114.1 - 1.1 9.0 11.8 1.5 8.6 11.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Band_3_cyto PF07565.13 RUS84114.1 - 1.3 8.8 8.2 1.7 8.4 8.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FemAB PF02388.16 RUS84114.1 - 1.4 7.7 13.5 1.9 7.2 13.5 1.1 1 0 0 1 1 1 0 FemAB family RNA_polI_A34 PF08208.11 RUS84114.1 - 1.4 8.9 41.5 2 8.4 41.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 V_ATPase_I PF01496.19 RUS84114.1 - 1.4 6.7 8.5 1.9 6.3 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF3_subunit PF08597.10 RUS84114.1 - 1.5 8.7 30.2 2.3 8.1 30.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1168 PF06658.12 RUS84114.1 - 1.7 8.5 33.5 2.3 8.0 33.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FAM176 PF14851.6 RUS84114.1 - 1.8 8.3 4.8 2.8 7.6 4.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF3530 PF12048.8 RUS84114.1 - 1.8 7.9 8.4 0.18 11.2 3.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) EOS1 PF12326.8 RUS84114.1 - 2.1 8.3 8.2 3.1 7.7 8.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein MDM10 PF12519.8 RUS84114.1 - 2.4 7.0 8.1 3 6.6 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sec62 PF03839.16 RUS84114.1 - 2.4 7.6 19.8 3.7 7.0 19.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3405 PF11885.8 RUS84114.1 - 3.3 6.2 10.9 4.6 5.7 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) AIF_C PF14721.6 RUS84114.1 - 3.7 7.9 10.3 5.5 7.4 10.3 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TMEM214 PF10151.9 RUS84114.1 - 3.9 5.8 20.8 5 5.5 20.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator EMC3_TMCO1 PF01956.16 RUS84114.1 - 4 7.1 12.2 5.9 6.6 12.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SRP-alpha_N PF04086.13 RUS84114.1 - 4.1 7.3 24.4 5.5 6.8 24.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDHD PF02862.17 RUS84114.1 - 4.3 7.4 12.0 5.2 7.2 12.0 1.2 1 1 0 1 1 1 0 DDHD domain Dendrin PF15498.6 RUS84114.1 - 4.5 5.9 13.8 6.2 5.4 13.8 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin ALMT PF11744.8 RUS84114.1 - 4.5 6.0 8.8 6.1 5.5 8.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_pol_Rpc4 PF05132.14 RUS84114.1 - 4.9 7.6 16.4 7.2 7.0 16.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Membralin PF09746.9 RUS84114.1 - 6.5 5.7 6.2 8 5.4 6.2 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF1682 PF07946.14 RUS84114.1 - 6.8 5.8 27.3 9.8 5.3 27.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Folate_carrier PF01770.18 RUS84114.1 - 7.2 5.2 8.9 9.3 4.9 8.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Phosphodiest PF01663.22 RUS84115.1 - 1.5e-69 235.3 4.6 1.4e-60 205.8 2.7 2.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS84115.1 - 1.3e-12 47.8 1.8 2.9e-05 23.6 0.1 2.6 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 RUS84115.1 - 3.8e-05 23.2 0.0 5.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 RUS84115.1 - 0.22 10.1 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) 7tm_1 PF00001.21 RUS84116.1 - 1.4e-07 31.1 16.0 2e-07 30.6 16.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84116.1 - 7.8e-06 25.7 14.0 1.3e-05 24.9 14.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx BUD22 PF09073.10 RUS84116.1 - 0.0024 17.3 28.2 0.003 17.0 28.2 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RUS84116.1 - 0.023 13.0 41.3 0.03 12.5 41.3 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 RUS84116.1 - 0.047 12.9 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 RUS84116.1 - 0.06 11.3 0.0 0.081 10.8 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 RUS84116.1 - 0.11 11.3 7.1 0.15 10.9 7.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 RUS84116.1 - 0.25 10.7 5.1 0.45 9.8 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CopD PF05425.13 RUS84116.1 - 3.5 8.1 8.6 1.6 9.1 1.2 2.7 2 0 0 2 2 2 0 Copper resistance protein D SAPS PF04499.15 RUS84116.1 - 3.7 6.2 14.0 4.8 5.9 14.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 RUS84116.1 - 5.5 6.3 48.6 8 5.8 48.6 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 RUS84116.1 - 7.7 6.1 14.2 10 5.7 14.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) VWD PF00094.25 RUS84117.1 - 0.04 14.2 0.1 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type D domain EB PF01683.18 RUS84118.1 - 0.061 13.6 2.5 0.2 12.0 2.5 1.8 1 0 0 1 1 1 0 EB module MRC1 PF09444.10 RUS84121.1 - 0.76 10.3 4.6 1.1 9.8 4.6 1.2 1 0 0 1 1 1 0 MRC1-like domain Pentapeptide_4 PF13599.6 RUS84123.1 - 0.13 12.4 0.0 3.2 8.0 0.0 2.3 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) G-7-MTase PF12803.7 RUS84123.1 - 7.3 5.7 8.9 1.4e+02 1.5 8.9 2.1 1 1 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) WW PF00397.26 RUS84124.1 - 9 6.5 11.1 0.33 11.1 4.8 1.9 2 0 0 2 2 2 0 WW domain Cwf_Cwc_15 PF04889.12 RUS84125.1 - 0.039 13.7 7.9 0.058 13.1 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RUS84125.1 - 0.99 8.7 11.5 1.7 7.9 11.5 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RUS84125.1 - 5 7.6 15.0 11 6.5 15.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 RUS84125.1 - 6.1 7.3 10.5 12 6.4 10.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nckap1 PF09735.9 RUS84127.1 - 0 1512.1 16.6 0 1512.0 16.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Sdh5 PF03937.16 RUS84128.1 - 2.8e-25 88.1 0.1 4.5e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TFIIE_alpha PF02002.17 RUS84128.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_17 PF13207.6 RUS84129.1 - 0.00078 19.9 0.0 0.002 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Phage_XkdX PF09693.10 RUS84129.1 - 0.011 15.8 0.1 0.053 13.6 0.1 2.1 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) YceD PF02620.17 RUS84129.1 - 0.22 11.7 2.0 0.42 10.7 0.0 2.3 3 0 0 3 3 3 0 Large ribosomal RNA subunit accumulation protein YceD RRM_1 PF00076.22 RUS84130.1 - 1.2e-36 124.3 1.8 3e-15 55.8 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 RUS84130.1 - 2.6e-18 66.1 0.0 5.8e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 RUS84130.1 - 0.00011 22.2 1.0 0.13 12.4 0.1 3.5 3 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS84130.1 - 0.027 14.5 0.2 25 4.9 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RUS84130.1 - 0.031 13.9 0.1 0.89 9.2 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 RUS84130.1 - 0.095 12.7 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif S1 PF00575.23 RUS84131.1 - 1.1e-13 51.3 0.0 4.5e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Rtf2 PF04641.12 RUS84131.1 - 0.0048 16.3 7.6 0.0048 16.3 7.6 2.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-CCHC_3 PF13917.6 RUS84131.1 - 0.0051 16.7 0.8 0.017 15.1 0.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 RUS84131.1 - 0.35 11.0 5.9 0.15 12.2 2.4 2.2 2 0 0 2 2 2 0 Zinc knuckle FancD2 PF14631.6 RUS84131.1 - 0.96 6.8 8.5 1.5 6.1 8.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease LRR_4 PF12799.7 RUS84132.1 - 0.0055 17.1 2.1 8.4 7.0 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS84132.1 - 0.34 11.1 3.1 20 5.6 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.7 RUS84133.1 - 7.9e-08 32.1 0.3 1.4e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS84133.1 - 0.00078 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain IL17 PF06083.11 RUS84134.1 - 1.1e-08 35.4 4.0 2.6e-08 34.2 4.0 1.6 1 0 0 1 1 1 1 Interleukin-17 Na_H_Exchanger PF00999.21 RUS84135.1 - 2.8e-10 39.5 30.0 7.1e-09 34.9 30.0 2.2 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Collagen_mid PF15984.5 RUS84136.1 - 2.2e-05 24.3 4.9 0.033 13.9 1.8 3.8 1 1 1 2 2 2 2 Bacterial collagen, middle region XhlA PF10779.9 RUS84136.1 - 0.00027 21.1 2.1 16 5.8 0.0 5.3 1 1 3 5 5 5 2 Haemolysin XhlA DUF16 PF01519.16 RUS84136.1 - 0.00031 21.2 31.5 0.55 10.7 10.5 4.1 1 1 2 3 3 3 3 Protein of unknown function DUF16 Zn_Tnp_IS1 PF03811.13 RUS84136.1 - 0.05 13.3 120.7 2.9 7.7 3.6 15.1 1 1 12 13 13 13 0 InsA N-terminal domain DUF948 PF06103.11 RUS84136.1 - 0.05 13.9 1.6 8.7 6.7 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) KH_5 PF13184.6 RUS84136.1 - 2.3 8.4 15.5 53 4.0 0.4 5.9 1 1 5 6 6 6 0 NusA-like KH domain Na_H_Exchanger PF00999.21 RUS84137.1 - 1.2e-24 86.8 34.0 3.6e-24 85.3 31.7 2.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1269 PF06897.12 RUS84137.1 - 0.21 11.9 0.2 0.21 11.9 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1269) zf-C4 PF00105.18 RUS84138.1 - 2.6e-26 91.9 14.2 7.3e-26 90.4 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS84138.1 - 0.00022 20.8 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor COesterase PF00135.28 RUS84139.1 - 6.4e-282 935.9 0.0 1.6e-143 479.3 0.0 3.0 3 0 0 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS84139.1 - 4.3e-23 82.3 4.1 1.5e-10 41.3 0.5 3.1 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS84139.1 - 4.3e-05 23.1 0.5 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RUS84139.1 - 0.0002 21.1 4.7 0.14 11.8 0.3 2.8 2 2 0 2 2 2 2 Putative esterase T2SS-T3SS_pil_N PF13629.6 RUS84139.1 - 0.0062 16.3 0.3 1.9 8.3 0.1 2.4 2 0 0 2 2 2 2 Pilus formation protein N terminal region Say1_Mug180 PF10340.9 RUS84139.1 - 0.03 13.2 1.7 9.7 4.9 0.2 3.6 2 2 0 2 2 2 0 Steryl acetyl hydrolase FTZ PF03867.14 RUS84139.1 - 0.053 13.0 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Ion_trans PF00520.31 RUS84140.1 - 4.7e-09 35.8 22.8 7e-09 35.3 22.8 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RUS84140.1 - 4.7e-05 22.3 13.6 7.4e-05 21.6 13.6 1.3 1 0 0 1 1 1 1 Polycystin cation channel RMI1_C PF16099.5 RUS84140.1 - 0.00056 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Ank_5 PF13857.6 RUS84140.1 - 0.012 15.9 0.0 0.081 13.3 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS84141.1 - 1e-17 64.5 3.0 4e-09 36.9 0.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS84141.1 - 5.4e-17 61.9 1.8 2.9e-08 34.1 0.2 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS84141.1 - 3.6e-14 52.6 3.6 2e-05 24.8 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS84141.1 - 1.5e-13 49.5 4.0 0.0016 18.7 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 RUS84141.1 - 3.4e-12 46.2 5.7 0.00043 20.6 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat zf-NOSIP PF15906.5 RUS84142.1 - 1.5e-40 137.2 0.5 3.5e-40 136.0 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 RUS84142.1 - 4.2e-11 42.7 2.8 4e-06 26.4 0.1 3.1 2 1 1 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 RUS84142.1 - 1.5e-06 28.3 0.1 0.11 12.7 0.0 2.7 3 0 0 3 3 3 2 U-box domain zf-Nse PF11789.8 RUS84142.1 - 7.9e-05 22.4 1.3 0.00073 19.3 0.2 2.7 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Prenylcys_lyase PF07156.14 RUS84143.1 - 1.2e-108 363.5 0.1 1.5e-108 363.2 0.1 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 RUS84143.1 - 1.8e-09 37.7 0.1 4.8e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 RUS84143.1 - 7.1e-07 28.9 0.1 1.6e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 RUS84143.1 - 0.018 14.7 0.2 0.037 13.6 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS84143.1 - 0.031 13.5 0.3 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RUS84143.1 - 0.037 14.0 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding zf-C2H2 PF00096.26 RUS84144.1 - 2.6e-07 30.7 22.7 0.056 13.9 0.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 RUS84144.1 - 1.3e-06 28.6 19.9 0.054 13.9 0.6 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RUS84144.1 - 3.1e-06 27.4 11.4 0.0015 18.8 0.0 4.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS84144.1 - 0.00013 21.6 15.0 0.00021 20.9 1.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS84144.1 - 0.0012 19.5 23.4 0.8 10.7 0.6 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 RUS84144.1 - 0.0022 18.2 15.2 0.013 15.8 3.3 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.15 RUS84144.1 - 0.0042 17.1 6.1 2.7 8.1 0.0 4.1 4 0 0 4 4 4 1 Sec23/Sec24 zinc finger OrsD PF12013.8 RUS84144.1 - 0.013 15.9 0.5 0.013 15.9 0.5 3.3 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-MIZ PF02891.20 RUS84144.1 - 0.19 11.5 7.6 1.3 8.8 2.1 3.2 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Actin_micro PF17003.5 RUS84144.1 - 0.2 10.8 13.6 1.6 7.8 0.0 3.9 2 2 2 4 4 4 0 Putative actin-like family zf-CHY PF05495.12 RUS84144.1 - 0.26 11.8 11.5 0.96 10.0 1.1 2.6 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_jaz PF12171.8 RUS84144.1 - 0.57 10.5 14.7 3.1 8.2 0.9 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 RUS84144.1 - 0.96 10.2 4.7 3.7 8.4 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon family Cas_CXXC_CXXC PF09706.10 RUS84144.1 - 1.7 9.0 5.2 10 6.4 0.0 3.4 4 0 0 4 4 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) Endonuclease_7 PF02945.15 RUS84144.1 - 2.4 8.1 9.5 0.081 12.9 1.3 2.5 2 1 1 3 3 3 0 Recombination endonuclease VII zf-C2H2_2 PF12756.7 RUS84144.1 - 2.7 8.4 14.2 2.5 8.5 0.4 3.6 2 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_10 PF10058.9 RUS84144.1 - 4.4 7.1 11.2 0.5 10.1 0.3 3.4 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD PF00628.29 RUS84144.1 - 4.5 7.2 12.1 7.1 6.6 2.6 3.3 2 2 1 3 3 3 0 PHD-finger zf_C2H2_ZHX PF18387.1 RUS84144.1 - 6.4 6.5 18.5 0.84 9.3 0.3 3.9 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-MYST PF17772.1 RUS84144.1 - 9.3 5.9 9.8 18 5.0 0.4 3.4 2 1 1 3 3 3 0 MYST family zinc finger domain PHD_2 PF13831.6 RUS84144.1 - 9.4 5.9 9.6 39 3.9 0.0 3.7 4 0 0 4 4 4 0 PHD-finger Spt5-NGN PF03439.13 RUS84145.1 - 5.4e-26 90.3 0.4 1.1e-25 89.3 0.4 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 RUS84145.1 - 1.4e-20 72.5 17.8 1.1e-07 31.5 1.5 6.1 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.8 RUS84145.1 - 1.4e-10 42.0 12.3 1.4e-10 42.0 12.3 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 RUS84145.1 - 0.031 14.5 1.2 0.39 11.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) DUF1529 PF07485.11 RUS84145.1 - 0.036 14.0 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) DUF4438 PF14505.6 RUS84145.1 - 0.08 11.9 1.5 12 4.8 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4438) Na_sulph_symp PF00939.19 RUS84146.1 - 3.5e-23 82.4 11.6 3.9e-23 82.2 11.6 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RUS84146.1 - 8.6e-10 38.3 9.8 9.5e-10 38.1 9.8 1.0 1 0 0 1 1 1 1 Citrate transporter DctM PF06808.12 RUS84146.1 - 0.0016 17.3 8.3 0.0025 16.7 8.3 1.4 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component DcuC PF03606.15 RUS84146.1 - 0.018 13.6 9.5 0.021 13.3 9.5 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF2933 PF11666.8 RUS84146.1 - 0.14 12.2 0.4 0.14 12.2 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) Kinesin PF00225.23 RUS84147.1 - 8.4e-117 389.8 0.0 8.4e-117 389.8 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 RUS84147.1 - 8e-23 81.0 0.0 8e-23 81.0 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding AAA_22 PF13401.6 RUS84147.1 - 0.1 12.9 0.4 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Kinesin_assoc PF16183.5 RUS84147.1 - 0.26 11.4 9.2 0.044 13.9 2.4 3.1 1 1 1 2 2 2 0 Kinesin-associated Cytochrom_C_2 PF01322.20 RUS84147.1 - 1.7 9.6 14.7 0.053 14.4 6.1 2.6 2 0 0 2 2 2 0 Cytochrome C' WD40 PF00400.32 RUS84148.1 - 3.9e-07 30.7 0.0 3.9e-07 30.7 0.0 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat Cupin_8 PF13621.6 RUS84149.1 - 3.9e-36 125.0 1.9 8.8e-35 120.6 0.2 2.9 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 RUS84149.1 - 0.0053 17.2 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RUS84149.1 - 0.0074 16.0 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 RUS84149.1 - 0.019 14.4 0.0 0.051 13.0 0.0 1.7 1 1 0 1 1 1 0 Cupin superfamily protein ARD PF03079.14 RUS84149.1 - 0.026 14.7 0.0 0.026 14.7 0.0 2.2 3 0 0 3 3 3 0 ARD/ARD' family LRR_8 PF13855.6 RUS84150.1 - 1.9e-14 53.1 9.2 2.8e-11 43.0 0.7 3.1 2 1 1 3 3 3 3 Leucine rich repeat Ig_3 PF13927.6 RUS84150.1 - 9.4e-08 32.6 0.0 2.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS84150.1 - 4e-07 30.0 0.0 8.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS84150.1 - 1.6e-05 25.1 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 RUS84150.1 - 1.8e-05 25.0 8.7 0.012 16.0 1.3 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) ig PF00047.25 RUS84150.1 - 0.00017 21.7 0.0 0.00073 19.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 RUS84150.1 - 0.0032 17.4 0.1 0.0064 16.4 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 RUS84150.1 - 0.0051 16.4 3.3 0.0091 15.6 2.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 RUS84150.1 - 0.015 15.8 11.1 0.79 10.5 0.0 5.1 5 1 0 5 5 3 0 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 RUS84150.1 - 0.07 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRRCT PF01463.24 RUS84150.1 - 0.082 13.5 0.1 0.28 11.8 0.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 RUS84150.1 - 0.32 11.1 2.2 22 5.4 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Prokineticin PF06607.11 RUS84152.1 - 0.0045 17.3 9.1 0.019 15.3 8.9 1.9 1 1 0 1 1 1 1 Prokineticin Metallothio_Euk PF12749.7 RUS84152.1 - 1.6 9.0 12.3 0.42 10.8 1.1 2.2 1 1 1 2 2 2 0 Eukaryotic metallothionein 5_nucleotid_C PF02872.18 RUS84153.1 - 7.1e-28 97.8 0.0 2.5e-27 96.0 0.0 1.9 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RUS84153.1 - 1.3e-10 42.1 0.3 2.2e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAM176 PF14851.6 RUS84153.1 - 2.9 7.6 4.5 8 6.1 4.5 1.7 1 0 0 1 1 1 0 FAM176 family CTD_bind PF04818.13 RUS84154.1 - 2.1e-15 57.3 0.4 2.1e-15 57.3 0.4 2.9 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CREPT PF16566.5 RUS84154.1 - 2.1e-07 31.2 1.9 7e-07 29.5 1.9 1.9 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour FapA PF03961.13 RUS84154.1 - 2.8 6.5 5.0 6.3 5.3 5.0 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHGN PF05679.16 RUS84155.1 - 5.8e-168 559.9 0.0 7e-168 559.6 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 RUS84155.1 - 5.7e-16 58.7 0.0 8.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 RUS84155.1 - 2.5e-10 39.9 0.3 5.6e-10 38.7 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS84155.1 - 3.4e-06 26.7 0.1 0.038 13.5 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 RUS84155.1 - 0.0035 17.2 0.1 0.018 14.8 0.1 2.2 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.6 RUS84155.1 - 0.093 12.2 0.0 0.67 9.4 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 21 RRM_1 PF00076.22 RUS84156.1 - 2.8e-35 120.0 0.5 1e-17 63.7 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS84156.1 - 7.3e-16 58.1 0.2 1.3e-07 31.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 RUS84156.1 - 0.015 15.5 0.0 7.9 6.7 0.0 3.2 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HtrL_YibB PF09612.10 RUS84157.1 - 1.9e-38 132.5 0.1 2.2e-38 132.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) 7tm_1 PF00001.21 RUS84158.1 - 1.2e-08 34.6 18.4 1.5e-08 34.3 18.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84158.1 - 2.5e-07 30.3 20.5 8.1e-07 28.6 20.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS84158.1 - 4.2e-05 23.3 20.7 4.2e-05 23.3 20.7 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Tubulin_C PF03953.17 RUS84160.1 - 2.9e-41 140.6 0.1 4.3e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 RUS84160.1 - 1.4e-40 139.6 0.1 2.4e-23 83.4 0.0 3.3 1 1 2 3 3 3 3 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 RUS84160.1 - 0.00044 20.5 0.0 0.005 17.1 0.0 2.5 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Carb_anhydrase PF00194.21 RUS84162.1 - 1.2e-57 195.4 0.0 2.6e-44 151.7 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF2475 PF10629.9 RUS84163.1 - 1.3e-11 44.5 2.1 1.3e-07 31.7 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2475) ROQ_II PF18386.1 RUS84164.1 - 8.4e-31 105.6 0.5 1.8e-30 104.5 0.5 1.6 1 0 0 1 1 1 1 Roquin II domain zf-CCCH PF00642.24 RUS84164.1 - 8.6e-07 28.7 2.9 1.6e-06 27.9 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS84164.1 - 3.5e-05 23.7 1.0 6.7e-05 22.8 1.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 RUS84164.1 - 0.062 14.0 0.2 0.16 12.7 0.2 1.7 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 RUS84164.1 - 0.07 13.0 1.2 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger RVT_1 PF00078.27 RUS84165.1 - 7.4e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 RUS84166.1 - 1.3e-12 47.6 14.6 1.6e-12 47.3 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84166.1 - 2.3e-09 37.0 19.1 3.5e-08 33.1 19.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS84166.1 - 1.4e-07 31.1 19.2 5.4e-07 29.3 19.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS84166.1 - 1.7e-06 27.9 15.6 1.7e-06 27.9 15.6 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 RUS84166.1 - 0.093 12.4 19.5 0.016 14.9 14.1 2.4 2 1 0 2 2 2 0 Srg family chemoreceptor E1-E2_ATPase PF00122.20 RUS84166.1 - 1.1 8.7 3.6 3.3 7.2 2.7 2.0 2 0 0 2 2 2 0 E1-E2 ATPase 7TM_GPCR_Srw PF10324.9 RUS84167.1 - 6.7e-13 48.6 14.8 8.7e-13 48.2 14.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS84167.1 - 1.2e-12 47.8 16.1 1.4e-12 47.6 16.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84167.1 - 3.6e-07 30.1 16.6 3.6e-07 30.1 16.6 1.9 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS84167.1 - 5e-07 29.4 19.6 1.3e-06 28.0 19.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.21 RUS84167.1 - 0.04 13.6 17.2 0.012 15.3 13.2 2.2 2 1 0 2 2 2 0 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 RUS84168.1 - 6.4e-11 42.4 15.6 6.4e-11 42.4 15.6 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS84168.1 - 3.6e-10 39.6 11.6 4.6e-10 39.3 11.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84169.1 - 1.3e-13 51.0 15.6 1.7e-13 50.5 15.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS84169.1 - 5.6e-08 32.4 19.5 6.9e-08 32.1 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84169.1 - 2.2e-06 27.5 21.5 2.2e-06 27.5 21.5 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS84169.1 - 0.00011 21.6 25.9 0.00058 19.3 25.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMCCDC2 PF15844.5 RUS84169.1 - 0.011 15.7 0.2 0.033 14.1 0.1 2.0 1 1 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 7TM_GPCR_Srx PF10328.9 RUS84170.1 - 3.8e-18 66.0 40.4 3.3e-10 40.0 20.5 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS84170.1 - 1.7e-13 50.5 39.0 5.1e-07 29.3 16.2 3.6 2 2 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84170.1 - 2.8e-11 43.3 44.9 8.1e-06 25.3 21.1 2.9 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Srg PF02118.21 RUS84170.1 - 1.8e-06 27.8 29.8 0.00019 21.2 10.7 3.9 1 1 1 3 3 3 2 Srg family chemoreceptor 7TM_GPCR_Sru PF10322.9 RUS84170.1 - 0.024 14.0 35.5 0.11 11.7 13.0 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srbc PF10316.9 RUS84170.1 - 0.039 13.5 39.2 0.069 12.6 11.5 3.9 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc DCA16 PF15349.6 RUS84170.1 - 0.046 13.3 0.6 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 PufQ PF05398.11 RUS84170.1 - 0.18 11.9 1.0 3.9 7.7 0.0 2.8 2 0 0 2 2 2 0 PufQ cytochrome subunit Herpes_US9 PF06072.11 RUS84171.1 - 0.96 9.4 0.0 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 YrhK PF14145.6 RUS84171.1 - 2.1 8.3 7.6 0.19 11.6 2.5 1.9 2 0 0 2 2 2 0 YrhK-like protein DUF4199 PF13858.6 RUS84172.1 - 0.00024 21.5 0.8 0.00024 21.5 0.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4199) SYS1 PF09801.9 RUS84172.1 - 0.19 11.9 4.4 0.12 12.5 2.0 2.0 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Ost5 PF05251.12 RUS84172.1 - 0.23 11.7 8.0 1.8 8.9 0.1 3.7 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 Wzy_C_2 PF11846.8 RUS84172.1 - 0.78 9.6 3.8 0.37 10.7 0.4 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal SPC25 PF06703.11 RUS84172.1 - 0.83 9.4 4.1 0.64 9.8 1.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Baculo_11_kDa PF06143.11 RUS84172.1 - 5.4 6.7 6.3 5.2 6.7 1.0 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Abhydrolase_1 PF00561.20 RUS84174.1 - 2.9e-18 66.5 0.2 6.9e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS84174.1 - 1.8e-17 64.7 0.2 2.9e-17 64.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS84174.1 - 6.1e-11 42.0 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 RUS84174.1 - 0.00047 18.8 0.0 0.0059 15.2 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.11 RUS84174.1 - 0.0095 15.3 0.0 3.6 6.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 RUS84174.1 - 0.032 14.1 0.0 0.088 12.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 RUS84174.1 - 0.084 13.0 0.0 17 5.4 0.0 2.9 3 0 0 3 3 3 0 Thioesterase domain LIDHydrolase PF10230.9 RUS84174.1 - 0.086 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ndr PF03096.14 RUS84174.1 - 0.18 10.5 0.0 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 Ndr family HVSL PF09749.9 RUS84176.1 - 6.4e-53 179.7 0.2 8.4e-53 179.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Alpha_kinase PF02816.18 RUS84177.1 - 7.2e-20 71.9 0.1 8.1e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family NIF PF03031.18 RUS84178.1 - 2.2e-23 82.8 0.6 5.5e-23 81.5 0.1 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Biotin_lipoyl_2 PF13533.6 RUS84178.1 - 1.1e-05 25.1 0.1 0.0012 18.6 0.1 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like BRCT PF00533.26 RUS84178.1 - 0.00039 20.7 0.0 0.0014 18.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.22 RUS84178.1 - 0.004 17.0 0.4 0.018 14.8 0.4 2.1 1 1 0 1 1 1 1 Biotin-requiring enzyme PTCB-BRCT PF12738.7 RUS84178.1 - 0.0055 16.6 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain PPDK_N PF01326.19 RUS84180.1 - 1.6e-72 244.5 0.2 2.9e-72 243.7 0.2 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Alpha-amylase PF00128.24 RUS84181.1 - 1.5e-61 208.9 0.6 2.1e-61 208.4 0.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 RUS84181.1 - 1.1e-17 63.3 0.3 2e-17 62.5 0.3 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Malt_amylase_C PF16657.5 RUS84181.1 - 0.00055 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain AmoC PF04896.12 RUS84181.1 - 0.017 14.4 0.2 0.035 13.4 0.2 1.4 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C RMP PF14996.6 RUS84182.1 - 7.2e-47 159.5 8.0 7.2e-47 159.5 8.0 1.8 1 1 1 2 2 2 1 Retinal Maintenance Pup PF05639.11 RUS84182.1 - 7 7.6 7.5 17 6.4 0.3 2.3 2 0 0 2 2 2 0 Pup-like protein Kelch_4 PF13418.6 RUS84183.1 - 6.1e-35 119.0 1.0 6.5e-07 29.3 0.0 6.4 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS84183.1 - 2e-28 98.1 8.7 1.7e-07 31.3 0.1 7.7 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS84183.1 - 3.3e-28 97.2 0.3 4.1e-07 29.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS84183.1 - 4.9e-20 71.1 2.5 5.5e-05 23.3 0.0 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS84183.1 - 1e-17 63.3 5.9 2.6e-05 24.0 0.0 7.1 6 2 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 RUS84183.1 - 7.7e-15 54.2 6.1 3.8e-08 32.8 0.0 6.4 6 1 0 6 6 6 3 Kelch motif DUF4110 PF13422.6 RUS84183.1 - 0.0009 19.3 0.0 0.0009 19.3 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) zf-CCHC PF00098.23 RUS84184.1 - 7e-08 32.2 3.5 1.8e-07 30.9 3.5 1.8 1 0 0 1 1 1 1 Zinc knuckle PX PF00787.24 RUS84184.1 - 0.0019 18.1 1.7 0.0045 17.0 1.0 1.9 2 0 0 2 2 2 1 PX domain C2-set_2 PF08205.12 RUS84185.1 - 2 8.6 4.8 0.37 10.9 0.1 2.3 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain EptA_B_N PF08019.12 RUS84185.1 - 5 7.0 6.1 1.1 9.1 0.8 2.3 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Glyco_hydro_20 PF00728.22 RUS84186.1 - 7.4e-82 275.6 2.8 7.4e-82 275.6 2.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 RUS84186.1 - 1e-14 55.4 0.0 1e-14 55.4 0.0 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 RUS84186.1 - 0.0041 17.9 0.0 0.015 16.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RskA PF10099.9 RUS84186.1 - 3.6 7.8 10.8 3.3 8.0 2.8 3.3 3 0 0 3 3 3 0 Anti-sigma-K factor rskA AIG2_2 PF13772.6 RUS84187.1 - 1.5e-16 60.5 0.1 3.3e-16 59.4 0.1 1.6 1 1 0 1 1 1 1 AIG2-like family GGACT PF06094.12 RUS84187.1 - 2.7e-06 28.0 0.0 6.3e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2795 PF11387.8 RUS84187.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) DDE_Tnp_1_7 PF13843.6 RUS84189.1 - 9.6e-14 51.4 0.2 1.7e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Transposase IS4 Med28 PF11594.8 RUS84189.1 - 0.029 14.5 0.2 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 28 UBA_3 PF09288.10 RUS84189.1 - 0.14 12.0 1.2 0.32 10.8 0.6 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Alpha_L_fucos PF01120.17 RUS84190.1 - 1e-123 413.3 11.6 1.4e-123 412.8 11.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 RUS84190.1 - 1.1e-23 83.5 0.2 2.1e-23 82.7 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 RUS84190.1 - 0.063 13.4 0.1 0.24 11.5 0.1 2.0 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator IRK_C PF17655.1 RUS84191.1 - 3.1e-75 251.6 0.0 4.8e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RUS84191.1 - 2e-61 206.0 2.4 2.9e-61 205.4 2.4 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RUS84191.1 - 0.00021 21.2 0.3 0.00038 20.4 0.3 1.5 1 0 0 1 1 1 1 Ion channel Med13_C PF06333.12 RUS84191.1 - 0.012 14.9 0.4 0.023 14.0 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Ion_trans PF00520.31 RUS84191.1 - 0.021 14.1 1.0 0.03 13.6 1.0 1.2 1 0 0 1 1 1 0 Ion transport protein Nop14 PF04147.12 RUS84191.1 - 0.038 12.2 2.5 0.05 11.8 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 RUS84191.1 - 0.11 12.2 9.9 0.22 11.2 9.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 RUS84191.1 - 0.26 11.4 7.7 0.046 13.9 3.9 1.7 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 RUS84191.1 - 0.27 9.5 4.6 0.47 8.7 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS84191.1 - 0.32 10.3 12.2 0.58 9.4 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RUS84191.1 - 0.39 9.8 14.4 0.63 9.1 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 RUS84191.1 - 0.39 10.6 3.7 0.62 9.9 3.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Utp14 PF04615.13 RUS84191.1 - 0.41 9.2 4.3 0.61 8.6 4.3 1.2 1 0 0 1 1 1 0 Utp14 protein CENP-B_dimeris PF09026.10 RUS84191.1 - 0.54 10.7 17.1 1 9.8 17.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 RUS84191.1 - 0.57 8.7 3.0 0.86 8.1 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 RUS84191.1 - 1.7 8.3 4.2 4.9 6.8 4.2 1.8 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 RUS84191.1 - 1.9 6.5 12.3 2.7 6.0 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 RUS84191.1 - 2.8 7.9 8.8 0.28 11.2 3.6 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Guanylate_cyc PF00211.20 RUS84192.1 - 2.3e-67 226.2 0.1 7.8e-67 224.4 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 RUS84192.1 - 2e-43 148.9 0.0 2.7e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS84192.1 - 1.1e-37 129.7 0.0 1.9e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS84192.1 - 3.1e-29 102.1 0.0 5.9e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 RUS84192.1 - 0.0011 18.5 0.2 0.0026 17.2 0.2 1.6 1 0 0 1 1 1 1 Heme NO binding associated CM1 PF03026.15 RUS84192.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M1 protein HrpB7 PF09486.10 RUS84193.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Peptidase_M17 PF00883.21 RUS84194.1 - 1.2e-122 409.1 0.1 1.5e-122 408.8 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 RUS84194.1 - 9.1e-14 51.4 0.9 2.4e-13 50.0 0.6 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain An_peroxidase PF03098.15 RUS84195.1 - 9.6e-151 502.9 0.0 2.1e-148 495.2 0.0 2.0 1 1 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 RUS84196.1 - 2.7e-136 455.3 2.7 1.4e-70 238.4 0.7 2.0 1 1 1 2 2 2 2 Animal haem peroxidase RVT_1 PF00078.27 RUS84197.1 - 0.00036 20.1 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 RUS84198.1 - 8.5e-28 97.4 9.8 1.1e-27 97.0 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS84199.1 - 3e-08 33.3 1.1 3e-08 33.3 1.1 1.6 2 0 0 2 2 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84199.1 - 7e-05 22.3 1.2 0.0001 21.8 1.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SID-1_RNA_chan PF13965.6 RUS84199.1 - 0.015 13.7 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pox_Ag35 PF03286.14 RUS84199.1 - 0.017 14.9 23.0 0.025 14.4 23.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 RUS84199.1 - 0.059 12.8 24.8 0.081 12.3 24.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TLP-20 PF06088.11 RUS84199.1 - 0.063 13.2 5.8 0.11 12.4 5.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SAPS PF04499.15 RUS84199.1 - 0.07 11.9 5.4 0.08 11.7 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 RUS84199.1 - 0.075 12.6 22.5 0.1 12.2 22.5 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS84199.1 - 0.076 12.3 18.2 0.12 11.6 18.2 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 RUS84199.1 - 0.09 13.0 27.6 0.15 12.3 27.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpc4 PF05132.14 RUS84199.1 - 0.098 13.1 8.8 0.13 12.6 8.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTPRCAP PF15713.5 RUS84199.1 - 0.099 12.9 22.0 0.17 12.1 22.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RAB3GAP2_C PF14656.6 RUS84199.1 - 0.1 10.8 3.2 0.12 10.6 3.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Nop14 PF04147.12 RUS84199.1 - 0.15 10.2 27.1 0.18 10.0 27.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RUS84199.1 - 0.18 10.7 8.9 0.25 10.3 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PIP5K PF01504.18 RUS84199.1 - 0.22 10.7 2.8 0.24 10.6 2.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Astro_capsid_p PF12226.8 RUS84199.1 - 0.25 10.4 17.2 0.35 10.0 17.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Mpp10 PF04006.12 RUS84199.1 - 0.26 9.7 30.2 0.32 9.4 30.2 1.0 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS84199.1 - 0.42 9.9 27.3 0.65 9.3 27.3 1.2 1 0 0 1 1 1 0 BUD22 DUF1754 PF08555.10 RUS84199.1 - 0.49 11.2 27.1 0.7 10.7 27.1 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FYDLN_acid PF09538.10 RUS84199.1 - 0.83 10.4 21.1 1.4 9.6 21.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 RUS84199.1 - 1.5 8.1 13.9 2.3 7.5 13.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RPN2_C PF18004.1 RUS84199.1 - 2.1 8.2 28.2 2.9 7.8 28.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC27 PF09507.10 RUS84199.1 - 2.2 7.6 25.2 3 7.1 25.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.17 RUS84199.1 - 2.4 8.3 6.8 3.5 7.7 6.8 1.2 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 RUS84199.1 - 2.7 6.9 31.6 3.6 6.5 31.6 1.1 1 0 0 1 1 1 0 Paf1 CPSF100_C PF13299.6 RUS84199.1 - 4.7 7.4 15.2 7.2 6.8 15.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal dsRBD2 PF17842.1 RUS84199.1 - 4.7 7.4 6.2 7.6 6.7 6.2 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 OATP PF03137.20 RUS84199.1 - 5.5 5.2 7.3 0.44 8.8 0.6 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAM60A PF15396.6 RUS84199.1 - 6.4 6.7 10.7 8.9 6.2 10.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A eIF3_subunit PF08597.10 RUS84199.1 - 7 6.5 30.8 10 5.9 30.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit VIR_N PF15912.5 RUS84199.1 - 7.3 6.1 14.7 9.3 5.8 14.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal NPR3 PF03666.13 RUS84199.1 - 8.9 5.0 15.6 11 4.7 15.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 RUS84199.1 - 9 5.7 19.4 13 5.1 19.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5523 PF17661.1 RUS84199.1 - 9.2 5.9 28.9 13 5.4 28.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RNase_H PF00075.24 RUS84200.1 - 2.5e-15 56.9 0.1 7.4e-14 52.1 0.1 2.3 1 1 0 1 1 1 1 RNase H TFIIA PF03153.13 RUS84200.1 - 0.001 19.2 20.6 0.0013 18.8 20.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 RUS84200.1 - 0.0031 15.8 25.0 0.0037 15.6 25.0 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 RUS84200.1 - 0.036 12.5 18.1 0.044 12.2 18.1 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS84200.1 - 0.057 12.8 18.3 0.074 12.4 18.3 1.3 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 RUS84200.1 - 0.39 10.7 33.2 2.4e+03 -1.6 33.2 2.4 1 1 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RUS84200.1 - 0.65 8.0 47.3 1 7.4 47.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 RUS84200.1 - 0.72 9.7 12.3 1.1 9.1 12.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 RUS84200.1 - 0.93 8.8 9.8 1.7 7.9 9.8 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 RUS84200.1 - 3.1 6.0 27.5 4.6 5.4 27.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS84200.1 - 6.7 6.0 34.9 12 5.2 34.9 1.3 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS84200.1 - 8 5.8 24.6 14 4.9 24.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT 7tm_1 PF00001.21 RUS84201.1 - 1.6e-11 44.0 5.4 2.9e-11 43.2 5.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84201.1 - 0.00029 20.2 0.6 0.00029 20.2 0.6 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw GLTT PF01744.20 RUS84201.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 GLTT repeat (6 copies) 7TM_GPCR_Srx PF10328.9 RUS84201.1 - 1.5 8.4 26.7 1.7 8.2 20.2 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF202 PF02656.15 RUS84201.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF202) SNF PF00209.18 RUS84202.1 - 2.5e-187 623.8 39.2 1e-130 437.0 18.9 2.0 1 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Orbi_NS1 PF01718.16 RUS84202.1 - 0.19 10.1 0.5 0.29 9.6 0.5 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein zf-C2H2 PF00096.26 RUS84203.1 - 2e-35 119.3 87.1 0.00014 22.1 0.6 11.7 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS84203.1 - 1.9e-29 99.8 76.3 0.0025 18.5 0.7 11.8 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS84203.1 - 2.8e-28 97.0 69.0 1.8e-07 31.3 0.0 11.2 11 0 0 11 11 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS84203.1 - 1e-06 28.9 66.1 0.02 15.1 2.7 10.7 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS84203.1 - 0.00046 20.5 53.9 0.2 12.1 0.1 9.8 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS84203.1 - 0.00069 19.6 2.8 0.00069 19.6 2.8 10.4 10 0 0 10 10 10 3 C2H2-type zinc finger GAGA PF09237.11 RUS84203.1 - 0.0011 18.8 6.2 2.4 8.0 0.0 4.1 4 0 0 4 4 4 2 GAGA factor BolA PF01722.18 RUS84203.1 - 0.0016 18.7 9.5 0.046 14.0 0.2 3.3 3 1 1 4 4 4 2 BolA-like protein zf-C2H2_11 PF16622.5 RUS84203.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 7.3 7 1 1 8 8 8 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 RUS84203.1 - 0.049 14.0 51.0 0.32 11.3 0.6 8.4 2 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) FtsA PF14450.6 RUS84203.1 - 0.22 12.0 1.4 7.2 7.1 0.2 2.5 2 0 0 2 2 2 0 Cell division protein FtsA zf_UBZ PF18439.1 RUS84203.1 - 0.38 10.4 38.2 2 8.1 0.9 7.9 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS84203.1 - 1.4 9.1 43.6 0.37 11.0 5.1 7.5 7 0 0 7 7 7 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 RUS84203.1 - 1.5 9.6 38.5 0.72 10.6 0.9 6.0 5 1 0 5 5 4 0 zinc-ribbon family Headcase PF16002.5 RUS84203.1 - 9.1 5.7 15.4 0.2 11.1 6.8 2.6 3 0 0 3 3 3 0 Headcase protein CPBP PF02517.16 RUS84204.1 - 0.051 13.9 0.8 0.1 13.0 0.8 1.8 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease DUF4371 PF14291.6 RUS84205.1 - 2.2e-07 30.8 0.2 6.7e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4371) GreA_GreB PF01272.19 RUS84205.1 - 7e-05 22.6 0.3 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Transcription elongation factor, GreA/GreB, C-term MucBP PF06458.12 RUS84205.1 - 0.011 16.7 1.3 7.1 7.7 0.1 2.5 2 0 0 2 2 2 0 MucBP domain Pep_deformylase PF01327.21 RUS84205.1 - 0.013 15.1 1.3 0.53 9.9 0.1 2.9 2 2 1 3 3 3 0 Polypeptide deformylase Mso1_Sec1_bdg PF14475.6 RUS84205.1 - 0.018 14.6 0.1 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Sec1-binding region of Mso1 FlgD_ig PF13860.6 RUS84205.1 - 0.021 14.7 0.4 6.5 6.7 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain DUF4317 PF14199.6 RUS84205.1 - 0.023 13.9 0.9 1.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) DUF3124 PF11322.8 RUS84205.1 - 0.03 14.5 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) LuxT_C PF18285.1 RUS84205.1 - 0.032 14.8 0.1 6 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain NT-C2 PF10358.9 RUS84205.1 - 0.034 13.9 0.3 0.64 9.7 0.1 2.5 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins GbpC PF08363.10 RUS84205.1 - 0.052 13.0 0.2 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Glucan-binding protein C IL3Ra_N PF18611.1 RUS84205.1 - 0.29 11.2 2.2 9.9 6.2 0.1 2.4 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain PIP49_C PF12260.8 RUS84206.1 - 4.2e-44 150.5 0.0 5.7e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 RUS84206.1 - 2.2e-06 27.6 1.1 2.2e-06 27.6 1.1 1.9 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 UPF0489 PF12640.7 RUS84209.1 - 2.8e-48 164.5 0.1 4.2e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 UPF0489 domain ANAPC10 PF03256.16 RUS84210.1 - 1.4e-71 240.0 0.0 1.7e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 RUS84210.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 RUS84210.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.7 1 1 1 2 2 2 0 PITH domain CMAS PF02353.20 RUS84211.1 - 1.8e-43 148.8 0.4 2.5e-43 148.4 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 RUS84211.1 - 5.2e-14 52.7 0.0 1.3e-13 51.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS84211.1 - 1.5e-13 51.2 0.0 2.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS84211.1 - 3.5e-12 46.5 0.0 5.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS84211.1 - 3.4e-11 43.8 0.0 6.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS84211.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS84211.1 - 8.1e-09 35.2 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 RUS84211.1 - 0.00025 20.5 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 RUS84211.1 - 0.00078 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 RUS84211.1 - 0.0042 16.8 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 RUS84211.1 - 0.0042 16.7 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) DUF938 PF06080.12 RUS84211.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.15 RUS84211.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.16 RUS84211.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 RUS84211.1 - 0.02 15.0 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.11 RUS84211.1 - 0.083 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 RUS84211.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 RUS84211.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Fasciclin PF02469.22 RUS84212.1 - 5.2e-49 165.7 0.1 1.7e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain TMEM89 PF15098.6 RUS84212.1 - 0.021 15.0 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 TMEM89 protein family DUF211 PF02680.14 RUS84212.1 - 0.11 12.7 4.6 0.16 12.1 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized ArCR, COG1888 Astacin PF01400.24 RUS84213.1 - 1.2e-57 194.6 0.1 2e-57 193.9 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 RUS84213.1 - 1.8e-12 47.6 17.0 1.9e-07 31.5 4.4 3.0 2 0 0 2 2 2 2 ShK domain-like Peptidase_M10 PF00413.24 RUS84213.1 - 0.0067 16.3 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 2 Matrixin Reprolysin_4 PF13583.6 RUS84213.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Herpes_UL25 PF01499.16 RUS84214.1 - 0.83 8.1 4.7 1.2 7.5 4.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Ski_Sno PF02437.17 RUS84215.1 - 5.2e-37 125.9 0.1 7.9e-37 125.3 0.1 1.3 1 0 0 1 1 1 1 SKI/SNO/DAC family MSL1_dimer PF16801.5 RUS84215.1 - 0.69 9.7 5.7 1.4 8.8 5.7 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Somatomedin_B PF01033.17 RUS84217.1 - 4.3e-06 27.0 9.3 4.3e-06 27.0 9.3 3.0 3 0 0 3 3 3 1 Somatomedin B domain Na_Ca_ex PF01699.24 RUS84218.1 - 1e-17 64.5 33.6 3.5e-14 53.0 14.1 3.4 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 RUS84218.1 - 6.2e-15 55.6 14.7 6.2e-15 55.6 14.7 5.3 6 1 0 6 6 6 2 Inner membrane component domain Orf78 PF06024.12 RUS84218.1 - 6.7 7.1 0.0 6.7 7.1 0.0 4.5 5 0 0 5 5 5 0 Orf78 (ac78) YccF PF03733.13 RUS84219.1 - 4.1e-15 56.2 7.1 4.1e-15 56.2 7.1 6.2 6 1 0 6 6 6 2 Inner membrane component domain Na_Ca_ex PF01699.24 RUS84219.1 - 6.8e-14 52.1 34.2 4e-10 39.8 17.1 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein AcrZ PF10766.9 RUS84219.1 - 0.8 9.3 9.0 9.6 5.9 0.3 4.1 3 0 0 3 3 3 0 Multidrug efflux pump-associated protein AcrZ Adeno_E3_14_5 PF04834.12 RUS84219.1 - 9.6 6.8 9.3 12 6.6 0.3 3.5 4 0 0 4 4 4 0 Early E3 14.5 kDa protein Sugar_tr PF00083.24 RUS84220.1 - 5.3e-25 88.2 9.7 1.2e-19 70.5 0.3 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS84220.1 - 4e-22 78.6 8.8 2.2e-18 66.3 0.5 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily SHIRT PF18655.1 RUS84220.1 - 0.15 12.6 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 SHIRT domain DUF2157 PF09925.9 RUS84220.1 - 0.16 11.8 5.9 4.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Sugar_tr PF00083.24 RUS84221.1 - 2.8e-08 33.1 10.9 3.7e-08 32.7 10.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Gate PF07670.14 RUS84221.1 - 0.015 15.6 0.0 0.1 12.9 0.0 2.3 2 1 0 2 2 2 0 Nucleoside recognition AlaE PF06610.13 RUS84222.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 L-alanine exporter Ig_6 PF18452.1 RUS84222.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Aa_trans PF01490.18 RUS84223.1 - 1.4e-58 198.6 19.6 2.1e-58 198.0 19.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CRPA PF05745.11 RUS84223.1 - 0.075 13.1 0.1 0.075 13.1 0.1 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Neur_chan_LBD PF02931.23 RUS84224.1 - 1.2e-39 136.0 1.7 1.4e-39 135.7 1.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain 4_1_CTD PF05902.13 RUS84227.1 - 4.6e-27 94.2 3.8 8.1e-27 93.4 3.8 1.4 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 RUS84227.1 - 6.2e-25 87.4 0.1 1.2e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS84227.1 - 2.3e-16 60.2 0.0 4.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS84227.1 - 3.1e-14 52.6 0.3 4.2e-13 49.0 0.1 2.4 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 RUS84227.1 - 8.9e-12 44.9 1.0 8.9e-12 44.9 1.0 2.2 2 0 0 2 2 2 1 FERM adjacent (FA) EGF_3 PF12947.7 RUS84229.1 - 0.051 13.8 1.4 0.14 12.4 1.4 1.7 1 0 0 1 1 1 0 EGF domain DUF3439 PF11921.8 RUS84233.1 - 1.1 9.3 15.0 3.2 7.7 15.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YebO PF13974.6 RUS84233.1 - 7.3 6.7 11.8 54 4.0 0.1 2.7 2 0 0 2 2 2 0 YebO-like protein Mucin PF01456.17 RUS84233.1 - 7.8 6.5 26.3 0.095 12.7 15.2 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF5561 PF17716.1 RUS84234.1 - 1e-62 211.7 0.0 5.5e-51 173.3 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5561) CBM_14 PF01607.24 RUS84235.1 - 1.6e-05 24.9 20.5 0.0012 18.9 4.5 3.1 2 1 1 3 3 3 2 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 RUS84235.1 - 2.7 8.0 8.1 1.4 8.9 2.0 2.7 2 1 0 2 2 2 0 Carbohydrate binding domain (family 19) YfhO PF09586.10 RUS84236.1 - 0.0087 14.4 5.1 0.012 13.9 5.1 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO FapA PF03961.13 RUS84236.1 - 0.056 12.1 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hydin_ADK PF17213.3 RUS84236.1 - 1.9 8.7 5.4 3.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SAM_1 PF00536.30 RUS84237.1 - 9.5e-06 26.0 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS84237.1 - 1.7e-05 24.8 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Lipocalin_7 PF14651.6 RUS84238.1 - 4.9e-07 29.7 2.2 5.8e-07 29.5 2.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EF-hand_4 PF12763.7 RUS84239.1 - 3.9e-38 129.6 0.0 1.1e-21 76.7 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 RUS84239.1 - 4.1e-09 35.3 0.4 0.00052 19.4 0.3 3.4 4 0 0 4 4 3 2 EF hand ERM PF00769.19 RUS84239.1 - 1.1e-07 32.0 19.4 1.7e-07 31.3 19.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family EF-hand_6 PF13405.6 RUS84239.1 - 3.9e-06 26.3 0.3 0.14 12.2 0.1 3.8 4 0 0 4 4 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS84239.1 - 6.4e-06 26.5 0.1 0.068 13.6 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS84239.1 - 0.00015 21.1 0.8 0.24 11.0 0.1 2.6 2 0 0 2 2 2 2 EF hand TRAF_BIRC3_bd PF16673.5 RUS84239.1 - 0.00039 20.2 2.1 0.00039 20.2 2.1 2.7 3 1 1 4 4 3 1 TNF receptor-associated factor BIRC3 binding domain Myosin_tail_1 PF01576.19 RUS84239.1 - 0.00044 18.2 31.8 0.00062 17.7 31.8 1.0 1 0 0 1 1 1 1 Myosin tail Spc7 PF08317.11 RUS84239.1 - 0.0013 17.7 26.1 0.0013 17.7 26.1 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein AAA_13 PF13166.6 RUS84239.1 - 0.0045 15.7 8.9 0.0045 15.7 8.9 2.1 1 1 1 2 2 2 1 AAA domain DUF4407 PF14362.6 RUS84239.1 - 0.0046 16.4 20.3 0.0087 15.4 20.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 RUS84239.1 - 0.025 15.1 41.5 0.6 10.6 12.9 2.7 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF3450 PF11932.8 RUS84239.1 - 0.028 13.7 32.9 0.12 11.6 12.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-hand_8 PF13833.6 RUS84239.1 - 0.031 14.1 3.5 4.1 7.3 0.6 2.9 3 0 0 3 3 3 0 EF-hand domain pair TMPIT PF07851.13 RUS84239.1 - 0.039 13.2 20.0 0.017 14.4 1.2 2.3 2 0 0 2 2 2 0 TMPIT-like protein TMF_DNA_bd PF12329.8 RUS84239.1 - 0.042 13.9 43.2 0.026 14.5 13.7 3.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 RUS84239.1 - 0.097 12.7 41.4 0.23 11.5 28.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 RUS84239.1 - 0.12 12.7 30.6 0.064 13.5 10.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) ATG16 PF08614.11 RUS84239.1 - 0.19 11.9 42.3 0.5 10.6 21.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YscO PF07321.12 RUS84239.1 - 0.28 11.1 29.8 0.12 12.3 9.2 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO DUF2968 PF11180.8 RUS84239.1 - 0.36 10.4 35.1 1.6 8.3 14.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.12 RUS84239.1 - 0.36 10.9 38.2 0.36 10.9 25.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 RUS84239.1 - 0.48 8.5 29.0 0.081 11.1 10.2 2.3 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA RasGAP_C PF03836.15 RUS84239.1 - 0.5 10.5 22.8 3.1 7.9 7.0 3.0 1 1 1 2 2 2 0 RasGAP C-terminus KASH_CCD PF14662.6 RUS84239.1 - 0.61 9.9 36.1 6.1 6.6 29.4 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 RUS84239.1 - 0.99 9.2 29.5 2.3 8.0 17.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4201 PF13870.6 RUS84239.1 - 1.1 8.9 32.9 3.2 7.5 24.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 RUS84239.1 - 1.3 7.8 12.8 2 7.2 12.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4472 PF14739.6 RUS84239.1 - 1.3 9.8 26.5 1.7 9.4 11.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4763 PF15960.5 RUS84239.1 - 1.4 8.2 33.2 0.66 9.2 11.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 RUS84239.1 - 1.6 8.8 25.0 1.8 8.7 8.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 RUS84239.1 - 3.1 8.5 37.1 0.1 13.2 12.9 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mt_ATP-synt_D PF05873.12 RUS84239.1 - 6.3 6.6 10.3 2.7 7.8 7.2 1.8 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Taxilin PF09728.9 RUS84239.1 - 6.4 5.9 37.5 7.4 5.6 18.5 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein MAD PF05557.13 RUS84239.1 - 8.5 4.6 36.3 14 3.8 35.6 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Filament PF00038.21 RUS84239.1 - 9 5.8 32.7 1e+02 2.3 32.8 2.0 1 1 0 1 1 1 0 Intermediate filament protein DAGK_cat PF00781.24 RUS84240.1 - 1.1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Med26 PF08711.11 RUS84241.1 - 1.7e-10 40.7 1.8 4.8e-10 39.3 1.8 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med26_C PF15693.5 RUS84241.1 - 1.3e-05 25.4 0.2 0.00011 22.5 0.0 2.5 2 0 0 2 2 2 1 Mediator complex subunit 26 C-terminal Ank_2 PF12796.7 RUS84242.1 - 1.7e-54 182.3 11.5 6.1e-19 68.4 0.5 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS84242.1 - 7e-35 119.0 9.6 4.3e-11 43.1 0.1 6.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS84242.1 - 8.4e-32 105.6 1.5 7.2e-05 22.9 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 RUS84242.1 - 9.6e-29 99.1 2.0 2e-08 34.3 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS84242.1 - 4.4e-27 93.3 12.8 2.8e-05 24.4 0.0 8.1 7 1 1 8 8 8 6 Ankyrin repeat CBFD_NFYB_HMF PF00808.23 RUS84243.1 - 1.2e-21 76.8 0.6 5.8e-21 74.5 0.7 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS84243.1 - 1.4e-15 57.8 0.4 1.4e-15 57.8 0.4 2.5 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 RUS84243.1 - 0.052 13.9 0.1 0.052 13.9 0.1 2.8 4 0 0 4 4 4 0 CENP-S associating Centromere protein X Med8 PF10232.9 RUS84244.1 - 3.3e-67 226.5 5.8 4e-67 226.2 5.8 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF2682 PF10909.8 RUS84244.1 - 0.094 13.2 0.2 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) PrmA PF06325.13 RUS84245.1 - 2.2e-08 33.8 0.2 4.6e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RUS84245.1 - 7e-07 29.9 0.0 1.8e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RUS84245.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 RUS84245.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 RUS84245.1 - 1.3e-05 25.2 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 RUS84245.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS84245.1 - 0.00027 21.5 0.0 0.00062 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 RUS84245.1 - 0.00028 20.8 0.1 0.00055 19.9 0.1 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_23 PF13489.6 RUS84245.1 - 0.00087 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS84245.1 - 0.0019 17.9 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 RUS84245.1 - 0.0019 18.0 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 RUS84245.1 - 0.0087 15.9 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 RUS84245.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DREV PF05219.12 RUS84245.1 - 0.068 12.3 0.1 0.19 10.8 0.1 1.7 1 1 0 1 1 1 0 DREV methyltransferase CARM1 PF11531.8 RUS84245.1 - 0.08 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal Methyltransf_32 PF13679.6 RUS84245.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain KH_6 PF15985.5 RUS84246.1 - 9.4e-15 54.7 0.5 2.2e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 KH domain fn3 PF00041.21 RUS84247.1 - 1.1e-06 28.9 3.9 1.4e-06 28.5 0.1 3.1 3 0 0 3 3 3 1 Fibronectin type III domain Shisa PF13908.6 RUS84247.1 - 0.003 17.8 0.1 0.003 17.8 0.1 2.4 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator ig PF00047.25 RUS84247.1 - 0.014 15.5 0.4 0.098 12.8 0.4 2.5 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 RUS84247.1 - 0.02 14.9 0.1 0.061 13.4 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS84247.1 - 0.18 12.4 2.7 0.34 11.5 0.1 2.9 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 RUS84247.1 - 0.8 10.1 6.2 0.24 11.7 0.4 3.1 2 0 0 2 2 2 0 Immunoglobulin domain NAC PF01849.18 RUS84248.1 - 4.6e-24 84.1 0.3 1e-23 83.0 0.3 1.6 1 0 0 1 1 1 1 NAC domain YSIRK_signal PF04650.17 RUS84248.1 - 0.1 12.4 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide SHNi-TPR PF10516.9 RUS84249.1 - 5.6e-14 51.3 0.2 1.2e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 RUS84249.1 - 1.3e-12 47.8 0.8 9.8e-07 29.0 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS84249.1 - 1.5e-09 37.3 0.2 4.2e-05 23.2 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS84249.1 - 3.8e-09 36.0 1.2 0.019 15.0 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS84249.1 - 3.6e-07 29.9 6.5 0.053 13.8 0.2 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS84249.1 - 0.00038 20.1 2.9 8 6.2 0.9 4.5 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 RUS84249.1 - 0.037 14.7 0.2 2 9.1 0.0 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS84249.1 - 0.043 14.4 1.6 12 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Collagen_mid PF15984.5 RUS84250.1 - 0.043 13.6 1.9 0.11 12.2 1.9 1.7 1 1 0 1 1 1 0 Bacterial collagen, middle region QWRF PF04484.12 RUS84250.1 - 5 6.8 11.9 6.7 6.4 2.2 2.1 1 1 1 2 2 2 0 QWRF family DAO PF01266.24 RUS84251.1 - 2.4e-38 132.6 0.0 2.8e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS84251.1 - 0.072 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 RUS84252.1 - 1.4e-31 110.4 0.2 1.8e-31 110.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Exo_endo_phos PF03372.23 RUS84252.1 - 0.082 12.4 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Profilin PF00235.19 RUS84253.1 - 7.9e-08 32.6 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Profilin EF-hand_1 PF00036.32 RUS84254.1 - 2.3e-20 70.5 14.5 3.3e-07 29.4 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RUS84254.1 - 1e-19 70.7 11.7 7.2e-14 52.0 2.1 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS84254.1 - 1.8e-17 62.0 9.6 5e-08 32.1 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RUS84254.1 - 3.9e-15 54.4 9.3 1.1e-06 28.1 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS84254.1 - 7.9e-14 51.2 16.1 6.4e-08 32.3 0.6 4.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS84254.1 - 0.0029 17.9 0.6 0.02 15.2 0.1 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 RUS84254.1 - 0.0087 16.1 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 RUS84254.1 - 0.087 12.8 5.3 1.9 8.5 0.3 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand AC_N PF16214.5 RUS84254.1 - 2.9 6.9 7.1 4.3 6.4 7.1 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CAF1 PF04857.20 RUS84255.1 - 1e-77 261.5 0.0 1.3e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 RUS84255.1 - 0.0081 15.9 0.2 0.13 11.9 0.1 2.3 2 0 0 2 2 2 1 3'-5' exonuclease RNA_bind PF08675.11 RUS84255.1 - 0.038 14.0 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding domain WD40 PF00400.32 RUS84256.1 - 2.3e-25 88.4 10.1 2.7e-05 24.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS84256.1 - 5.2e-13 49.1 0.3 0.21 11.9 0.0 6.7 3 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS84256.1 - 0.012 14.6 0.0 15 4.4 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1754 PF08555.10 RUS84256.1 - 1.9 9.3 22.3 0.14 13.0 13.5 2.8 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FancD2 PF14631.6 RUS84256.1 - 3.2 5.0 4.8 4.8 4.4 4.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SPATA3 PF15662.5 RUS84256.1 - 3.4 8.3 8.9 6.5 7.3 8.9 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DNA_pol_phi PF04931.13 RUS84256.1 - 7.4 4.5 20.9 12 3.8 20.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 RUS84257.1 - 7.8e-39 133.6 45.5 5.7e-31 107.7 34.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS84257.1 - 2.1e-11 43.3 23.7 2.5e-10 39.8 21.3 2.7 2 1 0 2 2 2 1 MFS_1 like family TRIC PF05197.13 RUS84258.1 - 9.1e-51 172.2 5.9 1.2e-50 171.7 5.9 1.1 1 0 0 1 1 1 1 TRIC channel TRIC PF05197.13 RUS84260.1 - 9.3e-80 266.7 4.1 9.3e-80 266.7 4.1 1.3 2 0 0 2 2 2 1 TRIC channel UPF0126 PF03458.13 RUS84260.1 - 0.037 13.9 1.9 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 UPF0126 domain AIRC PF00731.20 RUS84261.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 AIR carboxylase RhlB PF12300.8 RUS84261.1 - 0.033 14.3 0.5 0.044 13.9 0.5 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB VWD PF00094.25 RUS84262.1 - 1.1e-11 45.2 2.2 3.9e-11 43.5 2.2 2.1 1 0 0 1 1 1 1 von Willebrand factor type D domain Mitofilin PF09731.9 RUS84262.1 - 8.7 5.1 10.7 17 4.1 10.7 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TRC8_N PF13705.6 RUS84263.1 - 2.7e-125 419.1 43.4 3.3e-125 418.8 43.4 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 RUS84263.1 - 9.6e-08 32.2 11.4 2e-07 31.2 11.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS84263.1 - 1.2e-07 31.4 10.5 1.2e-07 31.4 10.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS84263.1 - 2.8e-06 27.1 10.9 6.4e-06 25.9 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS84263.1 - 4.4e-06 26.4 9.1 9.4e-06 25.4 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS84263.1 - 5.2e-06 26.6 12.0 3.4e-05 24.0 12.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RUS84263.1 - 5.7e-06 26.1 7.7 1.1e-05 25.1 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RUS84263.1 - 0.00025 21.0 6.2 0.00056 19.9 6.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS84263.1 - 0.0016 18.3 10.1 0.0031 17.4 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RUS84263.1 - 0.0019 18.2 7.0 0.026 14.6 7.0 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 RUS84263.1 - 0.013 15.3 8.4 0.03 14.1 8.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 RUS84263.1 - 1.1 9.5 8.3 11 6.3 8.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Laminin_G_3 PF13385.6 RUS84266.1 - 1.7e-09 38.0 0.1 2.2e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ribonuc_P_40 PF08584.11 RUS84266.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit C8 PF08742.11 RUS84267.1 - 0.022 15.2 0.6 0.03 14.7 0.6 1.2 1 0 0 1 1 1 0 C8 domain Homeodomain PF00046.29 RUS84269.1 - 4.6e-21 74.4 3.8 1.2e-20 73.1 3.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS84269.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.6 3 0 0 3 3 3 0 Homeobox KN domain PPP4R2 PF09184.11 RUS84269.1 - 3.4 7.2 17.7 3.5 7.1 1.3 2.2 2 0 0 2 2 2 0 PPP4R2 BTB PF00651.31 RUS84270.1 - 0.026 14.7 0.6 0.26 11.5 0.0 2.9 3 0 0 3 3 3 0 BTB/POZ domain BACK PF07707.15 RUS84270.1 - 0.044 13.9 1.9 0.11 12.6 1.2 2.1 2 1 0 2 2 2 0 BTB And C-terminal Kelch HLH PF00010.26 RUS84271.1 - 1.1e-17 63.7 2.7 2.1e-17 62.8 2.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 RUS84271.1 - 2e-15 58.1 0.2 2e-15 58.1 0.2 2.6 2 1 1 3 3 3 1 Neuronal helix-loop-helix transcription factor DUF3218 PF11508.8 RUS84271.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) CDC45 PF02724.14 RUS84271.1 - 4.5 5.4 8.7 6.4 4.9 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein 7tm_2 PF00002.24 RUS84272.1 - 2.1e-19 69.8 13.3 3.4e-19 69.1 13.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 RUS84274.1 - 1.9e-22 79.8 8.6 1.9e-22 79.8 8.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF373 PF04123.13 RUS84274.1 - 3.1 7.2 5.7 0.56 9.6 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) RasGEF PF00617.19 RUS84275.1 - 1.2e-48 165.6 0.1 3.7e-48 164.1 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 RUS84275.1 - 7e-13 48.2 9.7 1.4e-12 47.3 9.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_5 PF13202.6 RUS84275.1 - 1.7e-10 39.9 1.1 0.00019 20.8 0.1 2.5 2 0 0 2 2 2 2 EF hand RasGEF_N PF00618.20 RUS84275.1 - 1.8e-10 40.9 0.1 7.7e-10 39.0 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif EF-hand_1 PF00036.32 RUS84275.1 - 2.1e-09 36.2 3.7 0.00021 20.6 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS84275.1 - 4.8e-08 32.3 1.8 0.00048 19.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS84275.1 - 7.7e-07 29.5 0.4 0.015 15.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Csm1_N PF18504.1 RUS84275.1 - 0.051 13.9 0.5 0.13 12.7 0.5 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain SPARC_Ca_bdg PF10591.9 RUS84275.1 - 0.056 13.8 0.3 0.45 10.8 0.3 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 RUS84275.1 - 0.4 10.6 2.5 16 5.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair Clat_adaptor_s PF01217.20 RUS84276.1 - 1.4e-62 209.8 8.0 1.5e-62 209.7 8.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNA_pol_A_bac PF01000.26 RUS84277.1 - 1.5e-28 99.4 0.0 2.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RUS84277.1 - 1.6e-21 75.5 0.0 2.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TAF6_C PF07571.13 RUS84278.1 - 1.7e-20 73.1 0.0 5.2e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 RUS84278.1 - 0.0018 18.4 0.5 0.0075 16.4 0.4 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) MCM PF00493.23 RUS84279.1 - 3.8e-100 333.6 0.0 5.9e-100 333.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RUS84279.1 - 3e-38 130.5 0.3 5.3e-38 129.7 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS84279.1 - 8.9e-30 103.0 0.3 2e-29 101.9 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RUS84279.1 - 1.6e-17 63.9 0.4 4.9e-17 62.4 0.4 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RUS84279.1 - 1.9e-06 27.4 0.0 0.00042 19.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS84279.1 - 0.00037 20.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RUS84279.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS84279.1 - 0.011 15.5 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Glyc_hyd_38C_2 PF18230.1 RUS84280.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain CNRIP1 PF15043.6 RUS84281.1 - 6.9e-44 149.2 0.5 7.8e-44 149.0 0.5 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 PIG-H PF10181.9 RUS84282.1 - 1.4e-09 37.7 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Beta_helix PF13229.6 RUS84283.1 - 4.3e-21 75.4 4.3 4.3e-21 75.4 4.3 1.9 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 RUS84283.1 - 7.4e-15 54.9 1.7 7.4e-15 54.9 1.7 1.4 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.20 RUS84283.1 - 4.2e-10 39.7 13.7 7.6e-10 38.8 13.7 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Bcl-2 PF00452.19 RUS84284.1 - 1.7e-26 92.8 0.6 2.6e-26 92.2 0.6 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.17 RUS84284.1 - 0.025 14.4 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 Bcl-2_3 PF15286.6 RUS84284.1 - 0.061 14.0 0.1 0.09 13.4 0.1 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Metal_resist PF13801.6 RUS84284.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Imm74 PF15603.6 RUS84284.1 - 0.091 13.0 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 74 Ribosomal_L18_c PF14204.6 RUS84284.1 - 0.13 13.2 0.0 0.21 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region DUF2200 PF09966.9 RUS84284.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) PSRP-3_Ycf65 PF04839.13 RUS84285.1 - 0.11 12.7 0.7 0.26 11.5 0.2 1.8 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Neuralized PF07177.12 RUS84286.1 - 9.9e-93 308.0 0.0 2.1e-46 157.6 0.0 2.1 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 RUS84286.1 - 1.9e-13 50.0 13.3 4.3e-13 48.9 13.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS84286.1 - 5.2e-05 23.0 13.2 0.00011 21.9 13.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS84286.1 - 0.00041 20.6 14.7 0.0011 19.3 14.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.14 RUS84286.1 - 0.051 13.2 10.9 0.1 12.3 10.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.6 RUS84286.1 - 1.6 8.8 18.9 0.18 11.8 14.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS84286.1 - 1.8 8.5 15.1 3.9 7.4 15.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DC_STAMP PF07782.13 RUS84288.1 - 7.8e-51 172.6 0.4 7.8e-51 172.6 0.4 2.0 2 0 0 2 2 2 1 DC-STAMP-like protein UQ_con PF00179.26 RUS84289.1 - 9.1e-47 158.2 0.2 1.3e-46 157.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS84289.1 - 0.01 15.5 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Y_phosphatase PF00102.27 RUS84290.1 - 7.7e-77 258.0 0.1 1.4e-76 257.2 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 RUS84290.1 - 3.2e-28 98.5 0.0 6e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RUS84290.1 - 6.4e-10 39.3 0.1 1.4e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 RUS84290.1 - 0.0035 17.1 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS84290.1 - 0.039 14.1 0.4 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RUS84290.1 - 0.052 13.5 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family GDWWSH PF15667.5 RUS84291.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function with motif GDWWSH IQ PF00612.27 RUS84292.1 - 4.5e-11 41.5 14.2 2.5e-05 23.7 0.2 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif NDUF_B6 PF09782.9 RUS84292.1 - 0.027 14.6 1.5 0.047 13.8 1.5 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit IFT43 PF15305.6 RUS84293.1 - 1e-42 145.5 5.5 1.5e-42 145.0 5.5 1.3 1 0 0 1 1 1 1 Intraflagellar transport protein 43 ABC_membrane_2 PF06472.15 RUS84294.1 - 3.7e-61 206.9 3.9 5.3e-61 206.4 3.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RUS84294.1 - 5.7e-19 69.0 0.0 2.8e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RUS84294.1 - 0.00044 20.7 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RUS84294.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 RUS84294.1 - 0.016 15.0 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS84294.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 RUS84294.1 - 0.033 14.7 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RUS84294.1 - 0.047 13.5 0.7 0.085 12.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RUS84294.1 - 0.05 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS84294.1 - 0.052 13.3 0.5 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 RUS84294.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DLIC PF05783.11 RUS84294.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 RUS84294.1 - 0.18 12.3 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M8 PF01457.16 RUS84295.1 - 1.8e-39 135.8 2.8 2e-30 106.0 0.2 2.1 1 1 1 2 2 2 2 Leishmanolysin zf-C2H2 PF00096.26 RUS84296.1 - 3.8e-33 112.1 77.0 3.2e-05 24.2 0.8 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS84296.1 - 5.5e-23 80.3 62.6 0.00012 22.3 1.6 11.2 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS84296.1 - 5.8e-21 73.4 68.2 0.011 16.4 0.3 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-met PF12874.7 RUS84296.1 - 0.0015 18.8 51.8 0.003 17.9 0.5 8.7 9 0 0 9 9 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS84296.1 - 0.0019 18.2 56.5 0.0023 17.9 2.9 8.6 9 0 0 9 9 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS84296.1 - 0.0072 16.6 42.8 0.16 12.3 0.8 8.4 7 1 1 8 8 8 3 Zinc-finger double-stranded RNA-binding DUF2870 PF11069.8 RUS84296.1 - 0.091 13.2 0.7 0.38 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Zn-ribbon_8 PF09723.10 RUS84296.1 - 0.4 10.8 27.0 2.2 8.5 2.5 6.5 2 2 6 8 8 8 0 Zinc ribbon domain zf_ZIC PF18366.1 RUS84296.1 - 0.74 10.0 17.5 0.6 10.3 0.1 5.5 3 2 2 5 5 5 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 RUS84296.1 - 0.89 10.0 54.2 1.3 9.6 0.3 8.1 2 2 4 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Rep_fac-A_C PF08646.10 RUS84296.1 - 6.2 6.6 12.9 5.3 6.8 0.5 3.7 3 1 1 4 4 4 0 Replication factor-A C terminal domain PyrI_C PF02748.15 RUS84296.1 - 9.3 6.3 13.0 3.1 7.8 0.1 4.3 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HalOD2 PF18547.1 RUS84296.1 - 9.5 6.2 8.0 10 6.1 0.2 3.6 4 0 0 4 4 4 0 Halobacterial output domain 2 FDF PF09532.10 RUS84297.1 - 4.9e-18 65.9 12.0 4.9e-18 65.9 12.0 2.1 2 0 0 2 2 2 1 FDF domain UCH PF00443.29 RUS84298.1 - 1.4e-14 54.3 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Gemini_C4 PF01492.17 RUS84298.1 - 0.059 13.3 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Geminivirus C4 protein RCR PF12273.8 RUS84298.1 - 0.088 13.5 1.4 0.17 12.5 1.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2141 PF09912.9 RUS84298.1 - 0.12 12.3 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Cyclin_N PF00134.23 RUS84299.1 - 1.7e-15 56.9 0.0 3.1e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RUS84299.1 - 3e-10 40.7 0.0 3.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin TRPM_tetra PF16519.5 RUS84300.1 - 0.016 15.3 0.1 0.045 13.9 0.1 1.8 2 0 0 2 2 2 0 Tetramerisation domain of TRPM UQ_con PF00179.26 RUS84301.1 - 5.9e-47 158.9 0.0 7.5e-47 158.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SDA1 PF05285.12 RUS84302.1 - 0.00081 18.9 16.6 0.00098 18.6 16.6 1.1 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 RUS84302.1 - 0.0011 17.1 21.6 0.0013 16.9 21.6 1.2 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 RUS84302.1 - 0.0012 18.3 8.9 0.0012 18.3 8.9 1.1 1 0 0 1 1 1 1 BUD22 Connexin PF00029.19 RUS84302.1 - 0.01 15.6 7.7 0.012 15.3 7.7 1.1 1 0 0 1 1 1 0 Connexin Zip PF02535.22 RUS84302.1 - 0.074 12.3 0.3 0.068 12.4 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 RUS84302.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 DDHD domain MDM1 PF15501.6 RUS84302.1 - 0.15 11.1 8.9 0.17 11.0 8.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 PIP5K PF01504.18 RUS84302.1 - 0.16 11.2 4.1 0.21 10.8 4.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Mpp10 PF04006.12 RUS84302.1 - 0.19 10.1 23.4 0.23 9.9 23.4 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 RUS84302.1 - 0.28 10.6 9.2 0.32 10.4 9.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 RUS84302.1 - 0.35 9.6 4.9 0.4 9.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 RUS84302.1 - 0.44 10.6 22.7 0.71 10.0 22.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Eapp_C PF10238.9 RUS84302.1 - 0.51 10.4 4.4 0.64 10.1 4.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3408 PF11888.8 RUS84302.1 - 0.78 9.9 15.0 1.1 9.4 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RRN3 PF05327.11 RUS84302.1 - 0.88 8.0 12.2 1 7.9 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RPA43_OB PF17875.1 RUS84302.1 - 0.94 10.1 10.3 1.5 9.5 10.3 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I XAP5 PF04921.14 RUS84302.1 - 1.3 8.8 13.4 1.7 8.4 13.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator CPSF100_C PF13299.6 RUS84302.1 - 1.9 8.7 10.7 2.8 8.1 10.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 RUS84302.1 - 2 9.2 16.2 0.59 10.8 13.3 1.7 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) GEN1_C PF18380.1 RUS84302.1 - 2.8 8.9 14.3 7.1 7.6 14.3 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain NPR3 PF03666.13 RUS84302.1 - 3.1 6.5 7.2 4 6.1 7.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CSRNP_N PF16019.5 RUS84302.1 - 3.4 7.5 6.1 4.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Folate_carrier PF01770.18 RUS84302.1 - 3.7 6.2 5.3 4.8 5.8 5.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3391 PF11871.8 RUS84302.1 - 4 8.0 12.3 1.5 9.3 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) EIIBC-GUT_N PF03612.14 RUS84302.1 - 4 7.1 7.6 5.7 6.6 7.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HsdM_N PF12161.8 RUS84302.1 - 4.5 7.9 8.3 6.4 7.4 8.3 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain TRAP_alpha PF03896.16 RUS84302.1 - 4.7 6.3 15.5 6.3 5.9 15.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.18 RUS84302.1 - 4.8 6.0 23.2 6.3 5.6 23.2 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.14 RUS84302.1 - 4.8 5.3 22.4 5.8 5.1 22.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RUS84302.1 - 5.6 6.7 12.5 7.8 6.2 12.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RNA_pol_Rpc4 PF05132.14 RUS84302.1 - 8.1 6.9 11.0 16 5.9 11.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cnd2 PF05786.14 RUS84302.1 - 8.2 4.9 15.8 9.8 4.7 15.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF5523 PF17661.1 RUS84302.1 - 8.9 5.9 24.0 12 5.5 24.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2955 PF11168.8 RUS84303.1 - 0.014 15.2 1.9 0.37 10.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2955) DUF1280 PF06918.14 RUS84303.1 - 0.043 13.4 1.0 0.058 13.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) EGF PF00008.27 RUS84304.1 - 0.014 15.7 1.0 0.014 15.7 1.0 2.2 3 0 0 3 3 3 0 EGF-like domain Ribonuc_P_40 PF08584.11 RUS84304.1 - 0.32 10.2 3.1 0.69 9.1 3.1 1.5 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit RFXA_RFXANK_bdg PF15289.6 RUS84304.1 - 3.5 8.0 12.1 45 4.4 8.0 2.9 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Neur_chan_LBD PF02931.23 RUS84305.1 - 8.5e-39 133.2 0.7 1.8e-38 132.1 0.7 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS84305.1 - 6.3e-19 69.0 0.6 9e-19 68.5 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3943 PF13084.6 RUS84306.1 - 0.14 12.0 7.1 17 5.3 0.4 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3943) SNARE_assoc PF09335.11 RUS84306.1 - 0.32 11.5 14.4 6.6 7.3 0.3 4.5 2 2 3 5 5 5 0 SNARE associated Golgi protein Ycf66_N PF07444.11 RUS84306.1 - 2.4 8.4 23.9 0.099 12.8 2.1 3.6 1 1 3 4 4 4 0 Ycf66 protein N-terminus Band_7 PF01145.25 RUS84307.1 - 2e-12 47.5 0.2 3.5e-11 43.4 0.0 2.3 1 1 1 2 2 2 1 SPFH domain / Band 7 family PTS_IIA PF02255.16 RUS84307.1 - 0.22 11.6 3.3 0.55 10.3 3.3 1.7 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit 7TM_GPCR_Srw PF10324.9 RUS84308.1 - 8.8e-09 35.1 15.3 1.9e-08 34.0 15.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS84308.1 - 1.2e-07 31.3 16.6 2.6e-07 30.2 16.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84308.1 - 0.053 13.1 16.6 0.058 13.0 15.6 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1189 PF06691.11 RUS84308.1 - 0.24 10.9 6.2 0.042 13.4 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) SNARE_assoc PF09335.11 RUS84309.1 - 4.2e-20 72.4 7.9 4.2e-20 72.4 7.9 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein ECF-ribofla_trS PF07155.12 RUS84309.1 - 0.03 14.3 4.5 1.8 8.5 0.4 2.8 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component ThiW PF09512.10 RUS84309.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.4 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Phage_holin_5_2 PF16079.5 RUS84309.1 - 0.26 11.7 2.7 12 6.3 0.1 3.3 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Peptidase_M1 PF01433.20 RUS84310.1 - 8.4e-86 287.0 0.5 1.2e-85 286.5 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RUS84310.1 - 2.1e-43 148.7 0.0 3.2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 RUS84310.1 - 2.6e-39 135.6 0.0 9.4e-39 133.8 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Neur_chan_LBD PF02931.23 RUS84311.1 - 4.2e-21 75.4 0.1 5.1e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS84312.1 - 0.00046 20.3 1.3 0.00076 19.6 0.1 1.7 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region 7tm_1 PF00001.21 RUS84312.1 - 0.057 12.7 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Tetraspanin PF00335.20 RUS84312.1 - 0.14 11.8 0.8 0.28 10.9 0.8 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF3432 PF11914.8 RUS84313.1 - 0.0034 17.6 26.0 2.2 8.6 17.3 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) OMP_b-brl_2 PF13568.6 RUS84313.1 - 0.056 13.5 6.7 5.4 7.0 6.7 3.3 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain DUF1062 PF06353.12 RUS84313.1 - 0.38 11.6 6.6 26 5.6 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1062) DUF481 PF04338.12 RUS84313.1 - 0.45 10.5 24.6 6.8 6.6 2.8 3.8 1 1 0 2 2 2 0 Protein of unknown function, DUF481 3-dmu-9_3-mt PF06983.13 RUS84313.1 - 1 9.9 11.0 7.4 7.1 0.4 3.2 1 1 2 3 3 3 0 3-demethylubiquinone-9 3-methyltransferase Ran-binding PF05508.11 RUS84313.1 - 3.6 6.5 26.9 5.1 6.0 1.0 5.2 1 1 5 6 6 6 0 RanGTP-binding protein DUF1943 PF09172.11 RUS84313.1 - 8.5 5.5 34.1 34 3.5 8.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) ALO PF04030.14 RUS84314.1 - 3e-78 263.2 3.0 4.2e-78 262.8 3.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 RUS84314.1 - 5.2e-27 94.3 0.0 8.3e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain EF-hand_1 PF00036.32 RUS84315.1 - 0.043 13.4 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2799 PF10973.8 RUS84315.1 - 0.089 13.2 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) Pterin_4a PF01329.19 RUS84316.1 - 0.18 12.0 0.0 23 5.3 0.0 2.1 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Paramecium_SA PF01508.16 RUS84316.1 - 1.1 9.8 8.0 0.55 10.7 2.1 2.8 3 0 0 3 3 3 0 Paramecium surface antigen domain Pkinase PF00069.25 RUS84317.1 - 9.5e-26 90.7 0.0 1.5e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS84317.1 - 4.7e-17 62.1 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS84317.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PPR_1 PF12854.7 RUS84318.1 - 3.9 7.2 12.4 69 3.3 0.0 5.7 7 0 0 7 7 7 0 PPR repeat FAM124 PF15067.6 RUS84319.1 - 4.4e-38 131.2 0.0 1.6e-27 96.7 0.0 2.1 2 0 0 2 2 2 2 FAM124 family Ribonuclease PF00545.20 RUS84319.1 - 0.031 15.0 0.2 0.1 13.4 0.1 1.9 1 1 1 2 2 2 0 ribonuclease Collagen_mid PF15984.5 RUS84320.1 - 0.051 13.3 4.7 0.074 12.8 4.7 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region NPV_P10 PF05531.12 RUS84320.1 - 0.054 14.0 0.3 0.18 12.3 0.4 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS84320.1 - 0.21 11.9 2.0 1.9 8.8 2.0 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 RUS84321.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NNMT_PNMT_TEMT PF01234.17 RUS84322.1 - 0.041 13.1 0.2 0.057 12.6 0.2 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family RNase_H PF00075.24 RUS84323.1 - 9.6e-15 55.0 2.8 1.7e-14 54.2 0.2 2.6 3 1 0 3 3 3 1 RNase H RVT_3 PF13456.6 RUS84323.1 - 0.00012 21.9 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like DUF4948 PF16306.5 RUS84323.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4948) Alpha-mann_mid PF09261.11 RUS84323.1 - 1.2 9.3 5.0 0.65 10.2 0.1 2.7 2 1 0 2 2 2 0 Alpha mannosidase middle domain Glycogen_syn PF05693.13 RUS84324.1 - 0 1131.5 0.1 0 1131.2 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 RUS84324.1 - 1.3e-05 25.0 0.2 5.4e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 RUS84324.1 - 2.1e-05 24.1 0.0 0.00035 20.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RUS84324.1 - 0.00014 22.3 0.0 0.013 15.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RUS84324.1 - 0.011 15.7 0.2 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA PF00004.29 RUS84325.1 - 9.7e-17 61.6 0.0 1.4e-15 57.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RUS84325.1 - 3.7e-14 52.5 0.1 1e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 RUS84325.1 - 1.5e-06 27.9 0.1 4.8e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 RUS84325.1 - 1.9e-05 24.9 0.0 0.0024 18.2 0.0 3.1 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 RUS84325.1 - 4e-05 23.4 0.0 0.00031 20.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 RUS84325.1 - 8.5e-05 23.0 0.1 0.0021 18.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RUS84325.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RUS84325.1 - 0.00016 21.3 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 RUS84325.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein TsaE PF02367.17 RUS84325.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RUS84325.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS84325.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RUS84325.1 - 0.015 15.4 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 RUS84325.1 - 0.022 15.1 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RUS84325.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 RUS84325.1 - 0.034 14.1 0.1 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RUS84325.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RUS84325.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RUS84325.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HMG_box PF00505.19 RUS84327.1 - 1.7e-24 86.0 3.1 3.4e-24 85.1 3.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS84327.1 - 1.6e-08 35.0 0.5 4.9e-08 33.5 0.5 1.9 1 0 0 1 1 1 1 HMG-box domain G_path_suppress PF15991.5 RUS84327.1 - 0.25 11.4 18.0 0.91 9.6 5.9 2.5 3 0 0 3 3 3 0 G-protein pathway suppressor DUF2406 PF10295.9 RUS84327.1 - 0.33 11.6 0.0 0.33 11.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein (DUF2406) Sporozoite_P67 PF05642.11 RUS84328.1 - 1.3 7.0 19.3 1.6 6.8 19.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SAPS PF04499.15 RUS84331.1 - 0.18 10.6 5.4 0.19 10.5 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 RUS84331.1 - 0.53 9.6 23.2 0.66 9.3 23.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 RUS84331.1 - 1.1 7.4 34.2 1.3 7.1 34.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS84331.1 - 9.2 5.6 37.7 11 5.3 37.7 1.0 1 0 0 1 1 1 0 SDA1 AFP PF02420.15 RUS84332.1 - 3.4e-09 35.9 0.4 2.9e+02 2.4 0.0 10.4 11 0 0 11 11 11 0 Insect antifreeze protein repeat preATP-grasp_3 PF18301.1 RUS84332.1 - 0.00063 20.0 8.1 33 4.9 0.0 7.8 9 0 0 9 9 9 2 pre ATP-grasp 3 domain RVT_1 PF00078.27 RUS84333.1 - 8.9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AZUL PF16558.5 RUS84334.1 - 4.5e-16 58.8 1.1 4.5e-16 58.8 1.1 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Erf4 PF10256.9 RUS84335.1 - 4.6e-12 46.1 0.0 6.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3552 PF12072.8 RUS84338.1 - 6.7e-12 45.2 30.8 0.014 14.8 2.4 5.5 1 1 7 8 8 8 8 Domain of unknown function (DUF3552) DUF3585 PF12130.8 RUS84338.1 - 1e-07 32.2 42.9 1.7e+02 2.3 18.6 7.7 1 1 1 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Syntaxin_2 PF14523.6 RUS84338.1 - 0.0012 19.2 39.4 2.8 8.4 0.2 6.8 1 1 1 2 2 2 1 Syntaxin-like protein FlgN PF05130.12 RUS84338.1 - 0.27 11.8 29.3 19 5.8 1.7 5.9 1 1 3 4 4 4 0 FlgN protein SKA2 PF16740.5 RUS84338.1 - 2.4 8.0 38.9 5.5 6.8 4.3 4.6 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 2 SNF PF00209.18 RUS84339.1 - 4.6e-189 629.4 31.6 5.8e-189 629.1 31.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PIRT PF15099.6 RUS84339.1 - 0.089 12.4 1.5 1.1 8.8 0.2 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2827 PF10933.8 RUS84340.1 - 1.1e-05 24.3 5.5 0.42 9.2 0.1 4.7 1 1 4 5 5 5 5 Protein of unknown function (DUF2827) DUF1340 PF07067.11 RUS84340.1 - 0.00018 20.9 4.9 9 5.6 0.1 4.8 1 1 5 6 6 6 4 Protein of unknown function (DUF1340) NosD PF05048.13 RUS84340.1 - 0.0077 15.5 0.0 0.088 12.1 0.0 1.8 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Rad17 PF03215.15 RUS84341.1 - 2.4 8.0 7.2 1.2e+02 2.5 0.0 4.4 1 1 4 5 5 5 0 Rad17 P-loop domain TPR_6 PF13174.6 RUS84341.1 - 4.3 8.2 5.1 84 4.1 0.0 6.1 9 0 0 9 9 9 0 Tetratricopeptide repeat cNMP_binding PF00027.29 RUS84342.1 - 2.7e-20 72.2 0.1 6.5e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 RUS84342.1 - 0.027 14.2 0.3 0.067 12.9 0.2 1.7 2 0 0 2 2 2 0 Cupin domain SNF PF00209.18 RUS84345.1 - 1.4e-162 542.1 32.9 7.4e-162 539.7 32.9 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Bcl-2 PF00452.19 RUS84348.1 - 4.9e-15 56.0 0.0 9.3e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Kinocilin PF15033.6 RUS84348.1 - 0.28 10.8 1.4 0.9 9.2 0.1 2.0 2 0 0 2 2 2 0 Kinocilin protein Bcl-2 PF00452.19 RUS84349.1 - 9.8e-21 74.3 0.0 2e-20 73.3 0.0 1.5 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family zf-CCCH_4 PF18044.1 RUS84350.1 - 0.0044 16.8 6.2 0.0072 16.1 6.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 RUS84350.1 - 0.29 11.1 5.8 0.47 10.4 5.8 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RUS84350.1 - 0.35 11.4 4.5 0.62 10.6 4.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RUS84351.1 - 2.1e-05 24.7 2.1 4.1e-05 23.8 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 RUS84351.1 - 0.0002 21.2 8.5 0.00042 20.1 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS84351.1 - 0.0017 18.3 6.4 0.0017 18.3 6.4 2.7 2 1 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 RUS84351.1 - 0.011 15.5 2.7 0.011 15.5 2.7 2.1 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 RUS84351.1 - 0.019 15.7 1.4 0.019 15.7 1.4 2.8 2 1 1 3 3 3 0 Torus domain SelP_N PF04592.14 RUS84351.1 - 9.8 5.5 10.6 27 4.0 10.6 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tetraspanin PF00335.20 RUS84353.1 - 6.3e-53 179.8 9.8 7.2e-53 179.7 9.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Tweety PF04906.13 RUS84353.1 - 0.0023 16.7 6.4 0.018 13.7 0.5 2.2 2 0 0 2 2 2 2 Tweety DUF2207 PF09972.9 RUS84353.1 - 0.097 11.4 13.8 2.3 6.9 11.3 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF973 PF06157.11 RUS84353.1 - 0.43 9.6 4.2 0.27 10.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) MAP17 PF15807.5 RUS84353.1 - 0.45 10.7 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4870 PF09685.10 RUS84353.1 - 0.51 10.5 13.4 0.026 14.6 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF373 PF04123.13 RUS84353.1 - 1.1 8.6 7.5 0.069 12.6 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF898 PF05987.13 RUS84353.1 - 1.3 8.0 7.6 6.2 5.8 2.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Amastin PF07344.11 RUS84353.1 - 1.4 8.8 16.2 1.8 8.4 0.2 2.8 2 1 1 3 3 3 0 Amastin surface glycoprotein DUF2981 PF11200.8 RUS84353.1 - 3.1 7.5 8.2 1.8 8.2 5.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) DUF2614 PF11023.8 RUS84353.1 - 8.6 6.5 10.9 0.16 12.1 1.5 2.5 3 0 0 3 3 3 0 Zinc-ribbon containing domain GramPos_pilinD3 PF16570.5 RUS84356.1 - 0.057 14.1 2.2 1.3 9.8 0.3 2.1 1 1 1 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain RRM_1 PF00076.22 RUS84357.1 - 6e-17 61.2 0.0 8.9e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RUS84357.1 - 3.5e-05 23.7 5.1 0.0001 22.2 5.1 1.9 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 RUS84357.1 - 5.1e-05 23.3 0.0 0.00015 21.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC_3 PF13917.6 RUS84357.1 - 0.00057 19.8 1.1 0.0011 18.8 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 RUS84357.1 - 0.00064 19.3 0.0 0.00088 18.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rsa3 PF14615.6 RUS84359.1 - 0.022 14.3 0.2 0.077 12.6 0.2 1.9 1 1 0 1 1 1 0 Ribosome-assembly protein 3 DUF3917 PF13055.6 RUS84359.1 - 0.03 14.8 0.4 0.058 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) TraL PF07178.11 RUS84359.1 - 0.033 14.7 0.9 0.063 13.7 0.1 1.8 2 0 0 2 2 2 0 TraL protein DUF1510 PF07423.11 RUS84359.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) 7tm_1 PF00001.21 RUS84360.1 - 4.7e-34 117.9 3.9 6.5e-34 117.5 3.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84360.1 - 0.0017 17.8 0.3 0.0041 16.5 0.3 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Patatin PF01734.22 RUS84363.1 - 1.6e-10 41.5 0.1 6.4e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 Patatin-like phospholipase FAM221 PF14753.6 RUS84363.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein FAM221A/B RAG1 PF12940.7 RUS84364.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Methyltransf_25 PF13649.6 RUS84366.1 - 1.9e-12 47.7 0.0 2.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS84366.1 - 1.1e-11 45.2 0.0 1.6e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS84366.1 - 5.1e-07 30.4 0.0 7.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS84366.1 - 2e-06 27.3 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS84366.1 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS84366.1 - 0.0013 18.5 0.0 0.0046 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 RUS84366.1 - 0.0039 15.8 0.0 0.0046 15.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PDZ PF00595.24 RUS84368.1 - 3.7e-15 56.0 0.0 4.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS84368.1 - 2.5e-06 27.7 0.0 3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS84368.1 - 8.2e-06 25.6 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain zf-C4 PF00105.18 RUS84370.1 - 2.2e-32 111.3 14.4 4.1e-32 110.4 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS84370.1 - 5.2e-12 45.8 0.2 8.2e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SET PF00856.28 RUS84372.1 - 6.2e-13 49.5 0.1 1.8e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 SET domain BTB PF00651.31 RUS84373.1 - 1.6e-20 73.4 0.1 2.6e-19 69.5 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 RUS84373.1 - 1.1e-19 70.0 0.7 8.8e-07 29.0 0.0 5.5 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 RUS84373.1 - 1.2e-19 69.6 0.4 8e-09 34.9 0.0 5.3 5 1 0 5 5 5 3 Kelch motif BACK PF07707.15 RUS84373.1 - 6.4e-17 61.5 1.3 1e-16 60.9 0.5 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 RUS84373.1 - 1.6e-10 40.9 0.1 9.2e-07 28.8 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS84373.1 - 9.7e-09 35.3 0.7 0.0031 17.8 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS84373.1 - 8.7e-06 25.5 0.5 0.07 13.1 0.0 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 RUS84373.1 - 1.1e-05 25.3 0.2 0.16 12.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Arm PF00514.23 RUS84374.1 - 4.9e-86 280.4 16.4 1.2e-11 44.2 0.0 9.3 8 1 1 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 RUS84374.1 - 1.2e-23 83.3 4.3 1.6e-23 83.0 3.1 1.9 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 RUS84374.1 - 1.8e-23 81.9 4.8 1.9e-22 78.6 5.1 2.3 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 RUS84374.1 - 2e-21 76.0 2.3 2.8e-08 34.1 0.1 6.4 4 2 4 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 RUS84374.1 - 2.2e-18 66.4 0.0 1e-05 25.8 0.0 5.9 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 RUS84374.1 - 2.3e-17 61.6 3.5 0.006 16.7 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 RUS84374.1 - 5.5e-06 26.0 0.4 0.6 9.5 0.0 4.5 2 1 3 5 5 5 1 Armadillo-like Adaptin_N PF01602.20 RUS84374.1 - 1.5e-05 23.7 0.0 5.4e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 RUS84374.1 - 9.8e-05 22.5 0.0 3.3 7.9 0.0 4.3 4 1 1 5 5 5 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 RUS84374.1 - 0.0001 22.2 0.2 1.3 9.1 0.0 4.1 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 RUS84374.1 - 0.00026 21.1 0.2 1.2 9.2 0.0 3.6 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 RUS84374.1 - 0.0023 17.3 0.0 0.033 13.5 0.0 2.2 1 1 0 2 2 2 1 V-ATPase subunit H RTP1_C1 PF10363.9 RUS84374.1 - 0.029 14.5 0.3 16 5.7 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Mo25 PF08569.11 RUS84374.1 - 0.072 12.4 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Mo25-like DUF5564 PF17719.1 RUS84374.1 - 0.13 12.4 0.5 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5564) Glyco_hydro_25 PF01183.20 RUS84374.1 - 0.14 12.3 0.0 2.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases family 25 Exonuc_VII_L PF02601.15 RUS84376.1 - 0.066 12.8 18.0 0.42 10.1 9.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phostensin_N PF13916.6 RUS84377.1 - 3.9e-05 23.9 2.1 0.54 10.6 0.0 3.5 3 0 0 3 3 3 3 PP1-regulatory protein, Phostensin N-terminal DUF2119 PF09892.9 RUS84377.1 - 0.055 12.8 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) VHP PF02209.19 RUS84377.1 - 0.83 9.8 0.0 0.83 9.8 0.0 3.6 3 0 0 3 3 3 0 Villin headpiece domain Motile_Sperm PF00635.26 RUS84380.1 - 0.00017 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Toxin_29 PF08116.11 RUS84381.1 - 0.009 16.0 4.8 0.009 16.0 4.8 3.1 2 1 1 3 3 3 1 PhTx neurotoxin family Pkinase_Tyr PF07714.17 RUS84382.1 - 2.1e-84 282.9 0.0 2.9e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS84382.1 - 2.1e-37 128.9 0.0 3.2e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS84382.1 - 1.3e-27 95.7 0.2 4e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 RUS84382.1 - 8.9e-22 77.5 0.3 2e-09 37.9 0.0 4.1 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS84382.1 - 9.8e-22 77.0 1.5 6.4e-09 36.2 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS84382.1 - 3.5e-13 49.4 4.3 0.00038 20.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 RUS84382.1 - 3.8e-13 48.3 1.1 0.002 18.5 0.0 5.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS84382.1 - 9e-12 45.0 0.0 0.00026 21.2 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Kinase-like PF14531.6 RUS84382.1 - 0.0083 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS84382.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RUS84382.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lig_chan PF00060.26 RUS84383.1 - 1.6e-22 80.0 2.7 2.5e-22 79.3 2.7 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel CcmD PF04995.14 RUS84383.1 - 0.028 14.5 0.2 0.13 12.4 0.2 2.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PEP-CTERM PF07589.11 RUS84383.1 - 0.36 11.0 2.5 1.2 9.3 2.5 2.0 1 0 0 1 1 1 0 PEP-CTERM motif DUF4381 PF14316.6 RUS84383.1 - 0.77 10.0 3.6 27 5.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Med31 PF05669.12 RUS84384.1 - 0.00094 19.1 62.6 1.8e+04 -32.4 62.6 5.2 1 1 0 1 1 1 0 SOH1 Sugar_tr PF00083.24 RUS84386.1 - 1.3e-19 70.5 7.3 2e-19 69.8 7.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS84386.1 - 1.7e-06 27.3 20.2 2.2e-06 26.9 20.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I9 PF05922.16 RUS84386.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 Pox_polyA_pol PF03296.13 RUS84386.1 - 0.19 11.6 0.2 0.36 10.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain MFS_1 PF07690.16 RUS84387.1 - 4.2e-08 32.5 1.6 4.7e-08 32.3 1.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS84387.1 - 0.00066 18.7 5.5 0.00079 18.4 5.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2970 PF11174.8 RUS84387.1 - 0.034 14.0 1.5 0.089 12.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) LAMTOR5 PF16672.5 RUS84390.1 - 0.061 13.3 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 FAA_hydrolase_N PF09298.11 RUS84390.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal Pkinase_Tyr PF07714.17 RUS84391.1 - 1.5e-79 267.0 0.0 3.3e-65 219.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS84391.1 - 3.4e-41 141.4 0.0 5.2e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS84391.1 - 3.3e-17 62.3 0.0 6.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain zf-C3HC4 PF00097.25 RUS84391.1 - 8.9e-09 35.1 6.9 2.1e-08 33.9 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS84391.1 - 2.5e-08 33.8 8.9 5.8e-08 32.6 8.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RUS84391.1 - 2.4e-06 27.8 7.8 2.4e-06 27.8 7.8 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 RUS84391.1 - 7.1e-06 26.1 8.6 2.2e-05 24.5 8.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RUS84391.1 - 8e-06 25.7 6.7 2.2e-05 24.3 6.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS84391.1 - 1.7e-05 24.6 6.0 4e-05 23.4 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS84391.1 - 6.8e-05 22.6 8.7 0.00037 20.3 8.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Haspin_kinase PF12330.8 RUS84391.1 - 0.2 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Prok-RING_4 PF14447.6 RUS84391.1 - 7 6.6 15.7 0.14 12.0 7.7 2.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Elongin_A PF06881.11 RUS84392.1 - 0.00038 21.0 0.5 0.0014 19.1 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DHOR PF06537.11 RUS84392.1 - 0.0088 14.7 0.0 0.016 13.8 0.0 1.4 1 0 0 1 1 1 1 Di-haem oxidoreductase, putative peroxidase SlyX PF04102.12 RUS84392.1 - 1.1 10.0 3.9 9.8 6.9 1.6 3.0 3 0 0 3 3 3 0 SlyX Macoilin PF09726.9 RUS84392.1 - 8 4.9 19.4 16 3.9 19.4 1.4 1 0 0 1 1 1 0 Macoilin family DnaJ PF00226.31 RUS84394.1 - 1.3e-22 79.7 0.2 1.3e-22 79.7 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 RUS84394.1 - 0.0015 18.3 0.2 0.0069 16.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flg_hook PF02120.16 RUS84394.1 - 0.02 14.8 2.1 0.02 14.8 2.1 1.9 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK POTRA_1 PF08478.10 RUS84394.1 - 0.07 13.4 1.1 0.27 11.6 0.9 2.1 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Cullin PF00888.22 RUS84395.1 - 4.3e-203 676.3 21.5 5.4e-203 676.0 21.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RUS84395.1 - 9.6e-23 80.0 1.0 3.7e-22 78.1 1.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 RUS84395.1 - 0.002 18.2 0.2 0.002 18.2 0.2 3.5 2 1 1 3 3 3 1 SecA Wing and Scaffold domain DDE_1 PF03184.19 RUS84395.1 - 0.0075 15.9 1.8 0.048 13.3 0.0 2.9 3 0 0 3 3 3 1 DDE superfamily endonuclease WD40 PF00400.32 RUS84397.1 - 3.4e-12 46.7 12.6 0.033 15.1 0.0 6.0 5 1 0 5 5 5 3 WD domain, G-beta repeat AAA_15 PF13175.6 RUS84397.1 - 0.012 15.4 23.7 0.016 15.0 23.7 1.1 1 0 0 1 1 1 0 AAA ATPase domain SpoIIP PF07454.11 RUS84397.1 - 0.025 14.0 16.7 0.048 13.1 16.7 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 RUS84397.1 - 0.15 11.5 10.0 0.22 10.9 10.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 RUS84397.1 - 0.56 9.0 17.6 0.72 8.6 17.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF262 PF03235.14 RUS84397.1 - 0.59 10.3 10.9 0.83 9.8 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 RR_TM4-6 PF06459.12 RUS84397.1 - 0.6 9.9 32.1 0.85 9.4 32.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 RUS84397.1 - 1.3 7.7 23.3 1.8 7.3 23.3 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 RUS84397.1 - 1.5 5.8 17.4 1.9 5.5 17.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4228 PF14009.6 RUS84397.1 - 1.9 8.9 17.6 3.1 8.2 17.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) LicD PF04991.13 RUS84397.1 - 2.1 8.4 25.3 4.4 7.4 25.3 1.5 1 0 0 1 1 1 0 LicD family SOBP PF15279.6 RUS84397.1 - 2.2 8.8 14.9 3.1 8.3 14.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Membralin PF09746.9 RUS84397.1 - 2.7 6.9 15.9 3.7 6.5 15.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein NPR3 PF03666.13 RUS84397.1 - 3 6.6 33.2 4.5 5.9 33.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 RUS84397.1 - 3.4 6.6 27.5 4.6 6.1 27.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 RUS84397.1 - 4 6.3 11.6 6.1 5.7 11.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PDCD2_C PF04194.13 RUS84397.1 - 7 6.7 24.4 2.7 8.0 20.8 1.9 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Neur_chan_memb PF02932.16 RUS84397.1 - 7.4 6.5 18.4 11 6.0 18.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAC1F_C PF16885.5 RUS84397.1 - 8.5 5.9 12.6 12 5.5 12.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Sec62 PF03839.16 RUS84397.1 - 8.6 5.8 38.0 14 5.1 38.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SID-1_RNA_chan PF13965.6 RUS84397.1 - 9 4.6 7.5 12 4.2 7.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cornifin PF02389.15 RUS84398.1 - 0.22 11.7 0.8 0.48 10.6 0.8 1.8 1 1 0 1 1 1 0 Cornifin (SPRR) family COesterase PF00135.28 RUS84400.1 - 4.2e-145 484.5 0.0 4.8e-145 484.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS84400.1 - 9.3e-07 28.9 0.4 5.4e-06 26.4 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold HemolysinCabind PF00353.19 RUS84401.1 - 2.7e-12 46.4 4.8 0.0041 17.1 0.0 3.6 1 1 1 4 4 4 4 RTX calcium-binding nonapeptide repeat (4 copies) Collagen PF01391.18 RUS84401.1 - 1.3e-08 34.4 10.9 0.0075 16.0 10.9 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) RNR_inhib PF08591.10 RUS84401.1 - 0.024 15.9 7.1 1.7e+02 3.5 7.1 3.9 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor SCAN PF02023.17 RUS84404.1 - 3.8e-10 39.5 0.1 7.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 SCAN domain zf-CCHC PF00098.23 RUS84404.1 - 1.3 9.2 10.5 0.56 10.4 0.2 3.2 3 0 0 3 3 3 0 Zinc knuckle Trypsin PF00089.26 RUS84406.1 - 1.1e-17 64.7 0.0 1.1e-17 64.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS84406.1 - 0.00035 21.5 0.0 0.00042 21.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RUS84406.1 - 0.0078 16.6 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF2625 PF10946.8 RUS84406.1 - 0.019 14.1 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Aconitase PF00330.20 RUS84407.1 - 1.6e-165 551.6 0.0 5.5e-160 533.3 0.0 2.1 2 0 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RUS84407.1 - 1.4e-41 141.9 0.0 2.7e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Lectin_C PF00059.21 RUS84408.1 - 1.3e-10 42.0 0.0 2.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 RUS84408.1 - 0.0025 17.5 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like DmpG_comm PF07836.11 RUS84409.1 - 0.09 12.3 2.2 2.1 7.9 0.4 2.3 2 1 0 2 2 2 0 DmpG-like communication domain Trnau1ap PF17654.1 RUS84410.1 - 0.0015 19.4 2.7 2.2e+02 2.8 0.0 6.2 1 1 6 7 7 7 0 Selenocysteine tRNA 1 associated proteins DUF5346 PF17281.2 RUS84410.1 - 0.0098 15.9 2.5 3.9 7.5 0.1 3.2 1 1 3 4 4 4 1 Family of unknown function (DUF5346) Telomerase_RBD PF12009.8 RUS84410.1 - 0.011 15.8 2.2 7.4 6.7 1.9 3.2 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Serine_rich PF08824.10 RUS84410.1 - 0.014 15.4 1.9 1.7 8.6 0.1 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain Molydop_binding PF01568.21 RUS84410.1 - 0.026 14.6 0.4 12 5.9 0.0 3.0 1 1 3 4 4 4 0 Molydopterin dinucleotide binding domain DUF1175 PF06672.11 RUS84410.1 - 0.028 14.1 1.2 23 4.6 0.0 3.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1175) Myb_CC_LHEQLE PF14379.6 RUS84411.1 - 0.0012 18.5 15.9 1.2 8.9 0.1 5.0 1 1 3 4 4 4 4 MYB-CC type transfactor, LHEQLE motif Ins134_P3_kin_N PF17927.1 RUS84411.1 - 1.9 8.9 5.3 3.9 7.9 0.8 2.8 1 1 1 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LMBR1 PF04791.16 RUS84411.1 - 8.2 5.2 6.5 8.3 5.2 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Trigger_C PF05698.14 RUS84412.1 - 0.013 15.5 16.1 47 3.9 16.1 3.0 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF826 PF05696.11 RUS84412.1 - 0.1 12.7 30.3 1.8e+04 -14.9 30.3 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF826) Minor_tail_Z PF06763.11 RUS84412.1 - 0.22 11.3 11.6 8.5e+02 -0.4 11.6 3.0 1 1 0 1 1 1 0 Prophage minor tail protein Z (GPZ) HI0933_like PF03486.14 RUS84412.1 - 4.4 5.9 9.0 8.1 5.0 9.0 1.5 1 1 0 1 1 1 0 HI0933-like protein FHIPEP PF00771.20 RUS84412.1 - 8.3 4.7 6.2 14 4.0 6.2 1.5 1 1 0 1 1 1 0 FHIPEP family SIN1 PF05422.12 RUS84414.1 - 0.35 11.4 56.6 0.37 11.3 14.4 7.3 1 1 6 7 7 7 0 Stress-activated map kinase interacting protein 1 (SIN1) DNA_ligase_A_C PF04679.15 RUS84414.1 - 0.8 10.3 22.8 67 4.2 0.2 7.0 5 1 1 6 6 6 0 ATP dependent DNA ligase C terminal region Sporozoite_P67 PF05642.11 RUS84415.1 - 0.018 13.1 1.4 0.02 13.0 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 RUS84415.1 - 0.094 13.1 29.1 0.21 12.0 29.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain eIF-3c_N PF05470.12 RUS84415.1 - 0.12 10.7 0.3 0.099 10.9 0.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 RUS84415.1 - 0.9 8.8 7.5 1.1 8.5 7.5 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 RUS84415.1 - 2.4 7.9 7.5 1.7 8.4 5.9 1.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 RUS84415.1 - 3.6 7.3 7.8 7.6 6.2 7.8 1.6 1 0 0 1 1 1 0 FAM176 family Corona_NS2 PF04753.12 RUS84417.1 - 0.085 13.4 1.5 2.8 8.6 0.1 2.7 1 1 1 2 2 2 0 Coronavirus non-structural protein NS2 DUF1029 PF06269.12 RUS84418.1 - 1.2e-06 28.5 0.7 31 4.8 0.0 8.8 9 2 2 11 11 11 1 Protein of unknown function (DUF1029) RSV_NS2 PF03113.14 RUS84418.1 - 0.076 13.0 0.2 1.5e+02 2.4 0.0 4.8 4 3 2 7 7 7 0 Respiratory synctial virus non-structural protein NS2 SGP PF17228.2 RUS84418.1 - 0.27 12.1 7.2 1.2e+02 3.6 0.1 5.5 2 2 4 6 6 6 0 Sulphur globule protein OAD_gamma PF04277.13 RUS84419.1 - 0.45 11.2 31.2 12 6.5 0.8 5.0 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain DUF3955 PF13127.6 RUS84419.1 - 3.3 7.6 39.1 8.4 6.3 1.9 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3955) 12TM_1 PF09847.9 RUS84420.1 - 0.0021 17.2 0.7 0.0021 17.2 0.7 1.7 2 0 0 2 2 2 1 Membrane protein of 12 TMs CoA_binding_3 PF13727.6 RUS84420.1 - 0.066 13.2 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 CoA-binding domain DUF1056 PF06341.11 RUS84420.1 - 0.089 13.1 2.6 0.1 12.9 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) YibE_F PF07907.11 RUS84420.1 - 0.37 10.2 5.5 0.077 12.5 1.8 1.6 2 0 0 2 2 2 0 YibE/F-like protein Ras PF00071.22 RUS84421.1 - 6.2e-22 77.9 0.0 6.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS84421.1 - 5.3e-15 55.7 0.0 6.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS84421.1 - 1.4e-06 27.8 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS84421.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2171 PF09939.9 RUS84422.1 - 4.4e-10 39.7 14.1 0.18 12.1 0.2 6.2 3 1 3 6 6 6 6 Uncharacterized protein conserved in bacteria (DUF2171) Packaging_FI PF14000.6 RUS84422.1 - 3.9e-05 24.1 4.6 0.18 12.3 0.3 3.0 1 1 2 3 3 3 3 DNA packaging protein FI ZZ PF00569.17 RUS84422.1 - 0.00063 19.5 3.7 23 4.9 0.0 5.2 3 1 3 6 6 6 2 Zinc finger, ZZ type PRC PF05239.16 RUS84422.1 - 0.069 13.2 2.9 48 4.1 0.2 4.1 3 1 2 5 5 5 0 PRC-barrel domain Nitroreductase PF00881.24 RUS84422.1 - 7.7 6.5 8.2 23 5.0 1.3 2.1 1 1 1 2 2 2 0 Nitroreductase family Kelch_1 PF01344.25 RUS84424.1 - 2.7e-54 180.5 0.1 9.1e-10 38.0 0.1 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RUS84424.1 - 4.9e-48 159.9 0.2 1.2e-08 34.9 0.0 7.2 4 3 3 7 7 7 7 Kelch motif Kelch_4 PF13418.6 RUS84424.1 - 3.5e-36 123.0 1.4 1.4e-08 34.6 0.0 7.1 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS84424.1 - 1.1e-25 89.3 0.0 4.5e-08 33.2 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS84424.1 - 3.3e-25 87.6 0.1 0.00039 20.3 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 RUS84424.1 - 4.8e-23 80.2 1.8 5.9e-06 26.1 0.0 7.5 6 2 1 7 7 7 5 Kelch motif DUF1668 PF07893.13 RUS84424.1 - 0.00027 20.4 0.1 0.69 9.2 0.1 3.3 1 1 3 4 4 4 3 Protein of unknown function (DUF1668) Glyoxal_oxid_N PF07250.11 RUS84424.1 - 0.068 12.3 0.1 21 4.2 0.0 3.0 3 0 0 3 3 3 0 Glyoxal oxidase N-terminus Rad4 PF03835.15 RUS84424.1 - 0.072 12.8 0.0 0.36 10.5 0.0 2.2 3 1 0 3 3 3 0 Rad4 transglutaminase-like domain DUF4376 PF14301.6 RUS84425.1 - 0.058 13.8 0.0 21 5.6 0.0 3.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4376) DUF2000 PF09391.10 RUS84425.1 - 0.061 13.3 0.3 5.4 6.9 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2000) DENN PF02141.21 RUS84425.1 - 0.079 12.9 1.1 1.9 8.4 0.1 2.0 1 1 1 2 2 2 0 DENN (AEX-3) domain Hva1_TUDOR PF11160.8 RUS84425.1 - 0.1 12.8 0.2 36 4.6 0.0 3.1 3 0 0 3 3 3 0 Hypervirulence associated proteins TUDOR domain DUF5544 PF17698.1 RUS84425.1 - 0.15 12.1 1.2 3.2 7.9 0.2 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5544) Tantalus PF15386.6 RUS84425.1 - 0.22 11.7 8.3 36 4.6 0.1 5.2 1 1 3 4 4 4 0 Drosophila Tantalus-like GpcrRhopsn4 PF10192.9 RUS84427.1 - 2.4e-55 187.7 3.2 3.6e-55 187.2 3.2 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 RUS84427.1 - 5.3e-05 22.6 7.9 8.6e-05 21.9 7.9 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor BMC PF00936.19 RUS84428.1 - 2.4e-05 24.2 0.0 31 4.7 0.0 5.6 1 1 6 7 7 7 0 BMC domain Osteoregulin PF07175.11 RUS84428.1 - 0.00028 21.1 1.2 6.6 6.9 0.0 3.3 1 1 3 4 4 4 2 Osteoregulin Cbl_N2 PF02761.14 RUS84428.1 - 0.0022 18.7 7.7 25 5.6 0.1 4.0 1 1 1 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain DUF924 PF06041.11 RUS84428.1 - 0.018 15.2 3.6 5.3 7.1 0.9 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) CD45 PF12567.8 RUS84428.1 - 0.026 14.5 33.3 9.8 6.2 0.4 7.4 4 2 4 8 8 8 0 Leukocyte receptor CD45 YfhO PF09586.10 RUS84428.1 - 0.047 11.9 0.1 2.2 6.4 0.1 3.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO ADAM_CR_2 PF17771.1 RUS84428.1 - 0.093 13.3 29.2 13 6.4 1.9 6.6 1 1 6 7 7 7 0 ADAM cysteine-rich domain Baculo_LEF5_C PF11792.8 RUS84428.1 - 0.11 12.2 34.7 19 5.1 0.3 8.0 8 0 0 8 8 8 0 Baculoviridae late expression factor 5 C-terminal domain DUF641 PF04859.12 RUS84429.1 - 0.087 13.2 5.3 0.11 12.9 5.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Glyco_trans_1_2 PF13524.6 RUS84429.1 - 0.38 11.2 2.4 0.55 10.7 0.5 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF3432 PF11914.8 RUS84431.1 - 0.16 12.3 3.3 2.1 8.6 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Alpha_adaptin_C PF02296.16 RUS84432.1 - 2.3e-09 37.4 1.8 4.8 7.4 0.0 5.6 1 1 5 6 6 6 6 Alpha adaptin AP2, C-terminal domain GATase_4 PF13230.6 RUS84432.1 - 1.2e-07 30.9 0.9 0.14 11.1 0.1 3.2 1 1 3 4 4 4 4 Glutamine amidotransferases class-II DUF4097 PF13349.6 RUS84432.1 - 5.7e-05 22.6 0.0 7.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Putative adhesin Gp_dh_N PF00044.24 RUS84432.1 - 0.085 13.2 0.0 35 4.8 0.0 2.5 1 1 3 4 4 4 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HisKA_2 PF07568.12 RUS84432.1 - 2.9 8.1 8.4 82 3.4 0.4 3.3 1 1 3 4 4 4 0 Histidine kinase STIMATE PF12400.8 RUS84434.1 - 5.3e-34 117.5 8.0 8.3e-34 116.8 8.0 1.3 1 0 0 1 1 1 1 STIMATE family Globin PF00042.22 RUS84435.1 - 2.4e-11 44.2 0.0 3.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Globin DUF3819 PF12842.7 RUS84436.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) UPF0697 PF15117.6 RUS84436.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 BCHF PF07284.11 RUS84439.1 - 1.9 8.5 22.4 27 4.7 1.0 4.7 1 1 5 6 6 6 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF716 PF04819.12 RUS84440.1 - 2.9e-14 52.9 2.5 2.9e-14 52.9 2.5 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF716) RsgA_N PF16745.5 RUS84440.1 - 0.00032 20.4 0.1 0.00067 19.4 0.1 1.4 1 0 0 1 1 1 1 RsgA N-terminal domain DUF962 PF06127.11 RUS84440.1 - 0.29 11.2 3.9 0.17 12.0 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF4709 PF15821.5 RUS84442.1 - 4.7e-08 33.3 53.6 63 3.9 0.1 17.5 1 1 18 19 19 19 6 Domain of unknown function (DUF4709) Acetone_carb_G PF08882.11 RUS84442.1 - 0.018 15.2 35.0 1.2e+02 2.9 0.1 11.5 1 1 16 17 17 17 0 Acetone carboxylase gamma subunit Thioredoxin_12 PF18400.1 RUS84443.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PH PF00169.29 RUS84444.1 - 0.00097 19.6 0.0 0.0011 19.5 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS84444.1 - 0.049 14.1 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1523 PF07509.11 RUS84444.1 - 0.17 11.3 0.8 1.9 7.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1523) tRNA-synt_1e PF01406.19 RUS84445.1 - 7.7e-108 360.4 0.9 9.8e-108 360.0 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RUS84445.1 - 5.8e-09 35.2 0.4 0.0022 16.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RUS84445.1 - 2.7e-05 22.6 0.0 0.0001 20.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) ING PF12998.7 RUS84446.1 - 1e-17 64.5 3.6 1e-17 64.5 3.6 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RUS84446.1 - 9.1e-06 25.5 7.4 2.2e-05 24.2 7.4 1.7 1 0 0 1 1 1 1 PHD-finger SRP-alpha_N PF04086.13 RUS84446.1 - 0.014 15.3 5.8 0.018 15.0 5.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-HC5HC2H PF13771.6 RUS84446.1 - 0.099 12.9 2.4 0.38 11.0 2.4 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF5327 PF17261.2 RUS84446.1 - 0.27 12.0 8.6 4.4 8.1 8.6 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5327) ALMT PF11744.8 RUS84446.1 - 3.8 6.2 6.3 4.8 5.9 6.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 RUS84446.1 - 5.9 6.6 9.9 8 6.2 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMPIT PF07851.13 RUS84446.1 - 6.6 5.9 6.5 0.4 9.9 0.3 1.8 2 0 0 2 2 2 0 TMPIT-like protein dCMP_cyt_deam_1 PF00383.23 RUS84447.1 - 7.1e-54 179.9 3.4 1.8e-26 91.9 0.2 2.5 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RUS84447.1 - 1.6e-28 99.2 0.9 1.9e-13 50.3 0.2 2.4 2 0 0 2 2 2 2 MafB19-like deaminase SNAD4 PF18750.1 RUS84447.1 - 0.0018 18.4 2.7 0.48 10.6 0.1 2.7 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 RUS84447.1 - 0.0049 17.0 4.1 0.14 12.2 0.1 3.0 2 1 1 3 3 3 1 APOBEC3 Stealth_CR1 PF17101.5 RUS84447.1 - 0.025 14.3 0.7 16 5.3 0.0 4.0 4 0 0 4 4 4 0 Stealth protein CR1, conserved region 1 Peptidase_S7 PF00949.21 RUS84447.1 - 0.042 13.7 0.3 3.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease NAD1 PF18778.1 RUS84447.1 - 0.11 12.6 1.8 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 RUS84447.1 - 0.22 11.6 6.3 6.9 6.7 0.5 3.1 2 1 1 3 3 3 0 Bd3614-like deaminase APOBEC2 PF18772.1 RUS84447.1 - 0.28 11.2 3.1 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 APOBEC2 SHR-BD PF06650.12 RUS84448.1 - 3e-52 177.7 0.0 5.6e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 RUS84448.1 - 2.2e-26 92.7 7.5 2.2e-20 73.2 0.8 3.3 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 RUS84448.1 - 0.0033 17.8 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain GILT PF03227.16 RUS84450.1 - 5.8e-14 52.2 1.3 1.2e-13 51.2 1.3 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Sortilin_C PF15901.5 RUS84450.1 - 0.013 15.8 0.7 0.02 15.2 0.7 1.4 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, C-terminal Lectin_C PF00059.21 RUS84451.1 - 4.9e-10 40.1 0.5 6.7e-10 39.7 0.5 1.2 1 0 0 1 1 1 1 Lectin C-type domain YrpD PF15493.6 RUS84451.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, YrpD Rab_bind PF16704.5 RUS84451.1 - 0.24 11.5 0.1 0.43 10.6 0.1 1.3 1 0 0 1 1 1 0 Rab binding domain GSDH PF07995.11 RUS84452.1 - 2.7e-36 125.5 0.0 3.9e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 RUS84452.1 - 2e-09 37.5 5.1 3.7e-09 36.7 5.1 1.5 1 0 0 1 1 1 1 Folate receptor family Kelch_6 PF13964.6 RUS84452.1 - 0.019 15.2 0.1 0.86 10.0 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Fz PF01392.22 RUS84452.1 - 0.074 13.7 0.5 0.21 12.2 0.1 1.9 1 1 0 1 1 1 0 Fz domain GSDH PF07995.11 RUS84453.1 - 7.5e-25 87.9 0.0 7.5e-22 78.1 0.0 2.1 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Globin PF00042.22 RUS84455.1 - 1e-16 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 RUS84455.1 - 0.0069 16.3 0.1 0.019 14.8 0.1 1.7 1 1 0 1 1 1 1 Protoglobin Myb_DNA-bind_5 PF13873.6 RUS84455.1 - 0.04 14.0 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TPR_12 PF13424.6 RUS84456.1 - 1.1e-34 118.5 2.5 4.1e-13 49.4 0.1 5.7 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS84456.1 - 8.3e-33 110.9 5.9 1.4e-06 27.8 0.5 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 RUS84456.1 - 4.6e-31 105.8 3.1 1.7e-05 24.5 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS84456.1 - 3e-30 101.9 1.8 7e-06 25.8 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS84456.1 - 1.7e-22 77.7 11.1 9.2e-08 31.7 0.8 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS84456.1 - 2.9e-20 70.7 6.4 7.9e-06 25.5 0.2 6.5 8 0 0 8 8 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 RUS84456.1 - 4.3e-14 52.8 0.3 0.046 14.2 0.0 6.8 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS84456.1 - 1.9e-13 50.0 0.4 0.23 12.4 0.0 9.6 10 2 2 12 12 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS84456.1 - 4.5e-11 42.3 3.2 0.28 11.6 0.2 8.1 8 1 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS84456.1 - 1.8e-10 40.9 7.5 0.034 14.4 0.1 5.2 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 RUS84456.1 - 6.6e-09 35.6 0.3 4e-08 33.0 0.0 2.3 1 1 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 RUS84456.1 - 5.3e-08 33.0 6.9 0.072 13.8 0.1 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS84456.1 - 8.7e-07 28.5 2.0 0.38 10.5 0.6 5.4 6 1 0 6 6 5 2 TPR repeat TPR_16 PF13432.6 RUS84456.1 - 1.4e-06 28.8 0.0 0.59 10.8 0.0 5.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS84456.1 - 1.5e-05 25.0 0.8 0.3 11.3 0.0 4.1 4 1 0 4 4 3 2 Tetratricopeptide repeat SNAP PF14938.6 RUS84456.1 - 0.00098 18.6 10.8 0.014 14.8 3.2 3.9 3 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 RUS84456.1 - 0.0017 18.4 1.6 0.87 9.7 0.1 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 RUS84456.1 - 0.0036 17.0 4.8 1.5 8.5 0.1 3.7 1 1 1 3 3 3 1 26S proteasome subunit RPN7 MIT PF04212.18 RUS84456.1 - 0.0069 16.4 12.0 0.2 11.7 0.4 6.2 8 0 0 8 8 6 1 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 RUS84456.1 - 0.0089 15.5 12.4 0.12 11.8 0.1 3.9 5 1 0 5 5 5 2 Meiosis protein SPO22/ZIP4 like PPR PF01535.20 RUS84456.1 - 0.018 15.2 11.8 0.22 11.8 0.2 6.7 8 0 0 8 8 7 0 PPR repeat DUF2225 PF09986.9 RUS84456.1 - 0.056 13.2 4.2 0.12 12.1 2.3 2.3 2 1 1 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2989 PF11207.8 RUS84456.1 - 0.1 12.3 7.1 0.59 9.9 0.8 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2989) Clathrin PF00637.20 RUS84456.1 - 0.38 10.6 6.3 11 5.9 0.3 4.5 4 1 1 5 5 5 0 Region in Clathrin and VPS DUF4062 PF13271.6 RUS84457.1 - 4.6e-17 62.2 0.0 1.7e-16 60.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.12 RUS84457.1 - 1.1e-09 38.4 0.8 3e-09 37.0 0.2 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 RUS84457.1 - 8.8e-07 29.5 0.5 1.7e-06 28.5 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 RUS84457.1 - 0.00047 19.7 0.1 0.00087 18.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 RUS84457.1 - 0.0012 19.1 0.5 0.0031 17.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RUS84457.1 - 0.0012 18.8 1.2 0.0012 18.8 1.2 2.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 RUS84457.1 - 0.0013 19.3 1.7 0.002 18.6 0.4 2.0 2 1 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.18 RUS84457.1 - 0.011 15.1 0.2 0.041 13.2 0.1 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 RUS84457.1 - 0.023 14.6 0.2 0.062 13.2 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 RUS84457.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 RUS84457.1 - 0.053 13.6 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 RUS84457.1 - 5.2 6.8 8.6 0.53 10.0 0.3 2.2 1 1 1 2 2 2 0 AAA domain Ras PF00071.22 RUS84458.1 - 6.6e-43 146.1 0.0 7.9e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS84458.1 - 2.4e-18 66.5 0.0 3.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS84458.1 - 4.2e-07 29.6 0.0 4.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS84458.1 - 0.055 13.0 0.4 1.1 8.8 0.0 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain BH3 PF15285.6 RUS84459.1 - 1.4 8.8 3.1 27 4.7 0.1 2.9 3 0 0 3 3 3 0 Beclin-1 BH3 domain, Bcl-2-interacting Homeodomain PF00046.29 RUS84460.1 - 2.3e-18 65.8 5.7 4e-18 65.0 5.7 1.4 1 0 0 1 1 1 1 Homeodomain CDC45 PF02724.14 RUS84460.1 - 0.023 13.0 4.2 0.041 12.2 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 RUS84460.1 - 0.3 9.6 8.1 0.44 9.1 8.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 RUS84460.1 - 0.77 7.8 6.8 1.4 6.9 6.8 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 RUS84460.1 - 1.5 8.1 8.9 2.4 7.4 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 RUS84460.1 - 3.1 6.8 9.8 5 6.2 9.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 RUS84460.1 - 8.4 6.1 6.0 1.9 8.2 1.6 2.0 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 RUS84461.1 - 6.9e-63 214.1 34.7 2e-40 140.1 5.9 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 RUS84462.1 - 3.4e-07 30.4 9.5 0.00062 19.8 1.0 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RUS84462.1 - 1.5e-06 28.3 2.2 2.6e-06 27.5 2.2 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 RUS84462.1 - 0.0023 18.4 13.6 0.26 11.8 0.8 4.8 2 1 3 5 5 4 1 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 RUS84462.1 - 0.004 14.8 0.7 0.0054 14.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mitofilin PF09731.9 RUS84462.1 - 0.007 15.3 0.0 0.009 14.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.15 RUS84462.1 - 0.007 16.0 0.8 0.012 15.2 0.8 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit FliT PF05400.13 RUS84462.1 - 0.015 16.1 6.1 0.039 14.7 6.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT DUF1664 PF07889.12 RUS84462.1 - 0.017 15.2 3.7 0.13 12.3 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS84462.1 - 0.037 12.9 1.2 0.055 12.4 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.11 RUS84462.1 - 0.038 12.0 1.3 0.056 11.4 1.3 1.3 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.11 RUS84462.1 - 0.045 13.6 1.6 0.068 13.0 0.7 1.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 RUS84462.1 - 0.062 13.6 4.0 9.1 6.6 1.0 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) CK2S PF15011.6 RUS84462.1 - 0.063 13.2 1.9 0.72 9.7 1.9 2.5 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF4407 PF14362.6 RUS84462.1 - 0.067 12.5 1.3 0.1 11.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 RUS84462.1 - 0.18 12.1 4.1 0.64 10.4 1.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SOAR PF16533.5 RUS84462.1 - 0.25 11.3 0.9 2.2 8.3 0.0 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF948 PF06103.11 RUS84462.1 - 0.26 11.6 2.5 2.7 8.3 1.1 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.6 RUS84462.1 - 0.43 10.9 10.5 1.4 9.2 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) COG5 PF10392.9 RUS84462.1 - 1.5 9.0 6.2 0.88 9.7 2.9 2.3 2 1 0 2 2 1 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 RUS84462.1 - 4.3 7.4 5.2 13 5.7 1.2 2.7 1 1 1 2 2 2 0 Laminin Domain II HSBP1 PF06825.12 RUS84462.1 - 4.8 7.1 8.5 6 6.8 2.6 3.4 2 1 1 3 3 3 0 Heat shock factor binding protein 1 BST2 PF16716.5 RUS84462.1 - 7.8 7.2 8.1 6.3 7.5 1.3 3.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Somatomedin_B PF01033.17 RUS84463.1 - 1.4e-05 25.3 14.1 1.4e-05 25.3 14.1 2.2 2 0 0 2 2 2 1 Somatomedin B domain zf-C2H2_11 PF16622.5 RUS84464.1 - 2e-07 30.6 0.0 2e-07 30.6 0.0 9.0 10 0 0 10 10 10 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 RUS84464.1 - 0.00014 22.2 0.7 0.00014 22.2 0.7 15.8 17 0 0 17 17 17 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS84464.1 - 0.001 19.0 0.3 0.001 19.0 0.3 7.9 12 0 0 12 12 12 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS84464.1 - 0.0049 17.6 0.3 0.0049 17.6 0.3 17.2 18 0 0 18 18 18 7 C2H2-type zinc finger DUF243 PF03103.17 RUS84464.1 - 0.13 12.6 0.4 0.47 10.8 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF243) ADH_zinc_N PF00107.26 RUS84465.1 - 1.1e-18 67.5 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 RUS84465.1 - 4.1e-16 58.8 0.0 7.6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 RUS84465.1 - 3.2e-10 41.2 0.0 6.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SLC12 PF03522.15 RUS84465.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PGM_PMM_II PF02879.16 RUS84465.1 - 0.075 13.7 0.1 0.68 10.6 0.1 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DAO PF01266.24 RUS84466.1 - 3.8e-40 138.6 0.0 4.3e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Gly_acyl_tr_C PF08444.10 RUS84466.1 - 0.057 13.7 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region STELLO PF03385.17 RUS84467.1 - 2.2e-11 43.2 1.2 2.6e-08 33.1 0.6 2.2 2 0 0 2 2 2 2 STELLO glycosyltransferases LRR_6 PF13516.6 RUS84468.1 - 1.5e-17 62.0 8.3 0.00047 20.0 0.1 5.1 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RUS84468.1 - 0.00031 21.1 4.6 0.62 10.6 0.0 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS84468.1 - 0.00081 19.1 4.1 2.9 7.7 0.0 4.3 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 RUS84468.1 - 0.0024 18.2 0.1 33 5.6 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat WD40 PF00400.32 RUS84469.1 - 4.9e-11 43.0 8.3 0.00014 22.6 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS84469.1 - 2.3e-08 34.2 0.0 0.0033 17.7 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS84469.1 - 0.0012 18.8 0.0 0.047 13.6 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RUS84469.1 - 0.031 13.6 0.0 4.1 6.6 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain zf-C3HC4_3 PF13920.6 RUS84470.1 - 1e-05 25.3 7.9 2.6e-05 24.0 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS84470.1 - 3.7e-05 23.6 10.2 9.5e-05 22.3 9.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS84470.1 - 5.7e-05 23.4 7.4 0.00016 21.9 7.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS84470.1 - 7.2e-05 22.5 7.7 7.2e-05 22.5 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS84470.1 - 0.00017 21.5 1.7 0.00017 21.5 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS84470.1 - 0.00028 20.7 8.3 0.00067 19.5 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS84470.1 - 0.00058 19.7 5.8 0.00058 19.7 5.8 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 RUS84470.1 - 0.008 16.3 2.0 0.018 15.2 2.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Vps36-NZF-N PF16988.5 RUS84470.1 - 0.048 13.1 2.7 0.58 9.6 0.8 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-rbx1 PF12678.7 RUS84470.1 - 0.097 13.0 6.9 0.3 11.4 6.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RUS84470.1 - 0.19 11.9 8.8 0.12 12.6 2.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RUS84470.1 - 0.56 10.1 6.3 0.32 10.9 3.5 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 RUS84470.1 - 0.57 10.0 7.5 2 8.3 7.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Glutaredoxin PF00462.24 RUS84471.1 - 1.5e-19 69.9 0.1 7.1e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Helicase_C PF00271.31 RUS84472.1 - 3.3e-14 53.2 0.0 1.4e-13 51.1 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 RUS84472.1 - 4.2e-12 46.3 0.2 1.7e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) TUDOR PF00567.24 RUS84472.1 - 1e-09 38.5 0.0 1e-08 35.2 0.0 2.5 1 1 0 1 1 1 1 Tudor domain DEAD PF00270.29 RUS84472.1 - 6.5e-09 35.8 0.1 1.8e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 RUS84472.1 - 0.00015 21.7 0.5 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RUS84472.1 - 0.0011 18.9 0.2 0.022 14.8 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 RUS84472.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf-met PF12874.7 RUS84472.1 - 0.012 16.0 0.3 0.012 16.0 0.3 2.1 2 0 0 2 2 1 0 Zinc-finger of C2H2 type PhoH PF02562.16 RUS84472.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 RUS84472.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS84472.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 RUS84472.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 RUS84472.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 RUS84472.1 - 0.054 14.0 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RUS84472.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 RUS84472.1 - 0.12 12.9 0.0 0.48 10.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF4585 PF15232.6 RUS84472.1 - 0.15 12.1 0.0 0.59 10.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) zf-U1 PF06220.12 RUS84472.1 - 0.16 11.8 0.2 0.67 9.8 0.2 2.0 1 0 0 1 1 1 0 U1 zinc finger Eapp_C PF10238.9 RUS84472.1 - 0.54 10.3 4.0 0.2 11.7 0.6 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein PhyH PF05721.13 RUS84473.1 - 6.7e-20 72.3 0.0 1.4e-19 71.2 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Kelch_4 PF13418.6 RUS84474.1 - 8.5e-40 134.5 18.0 7.5e-11 41.9 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS84474.1 - 1.1e-23 82.6 12.5 5e-05 23.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 RUS84474.1 - 1.6e-23 82.2 7.9 0.0016 18.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RUS84474.1 - 2e-20 72.6 10.1 0.00042 20.5 0.0 7.2 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS84474.1 - 4.5e-16 58.2 9.1 0.00056 19.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 RUS84474.1 - 7.1e-09 35.3 17.7 0.0043 17.0 0.1 6.6 6 0 0 6 6 6 4 Kelch motif HMG_box PF00505.19 RUS84475.1 - 5.7e-16 58.7 0.1 5.7e-16 58.7 0.1 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS84475.1 - 2.3e-10 40.9 1.4 4.9e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 HMG-box domain RNA_pol_Rpb2_5 PF04567.17 RUS84475.1 - 0.19 12.3 0.2 0.87 10.2 0.2 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Ras PF00071.22 RUS84476.1 - 7.7e-47 158.9 0.0 9.8e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS84476.1 - 2.8e-17 63.0 0.0 5.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS84476.1 - 8.7e-07 29.0 0.7 0.0051 16.7 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 RUS84476.1 - 1e-05 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS84476.1 - 0.0008 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS84476.1 - 0.0041 17.5 0.2 0.066 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 RUS84476.1 - 0.0061 16.1 0.1 0.041 13.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 RUS84476.1 - 0.011 14.7 0.1 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 RUS84476.1 - 0.054 13.8 0.3 0.47 10.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS84476.1 - 0.057 13.1 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RUS84476.1 - 0.059 13.6 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain HRM PF02793.22 RUS84478.1 - 8.5e-08 32.4 1.9 1.2e-07 31.9 1.9 1.3 1 0 0 1 1 1 1 Hormone receptor domain PRP38_assoc PF12871.7 RUS84478.1 - 0.0033 18.0 26.7 0.0069 17.0 26.7 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 PF13054.6 RUS84478.1 - 0.9 9.5 5.1 1.5 8.8 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GAIN PF16489.5 RUS84479.1 - 1.6e-28 99.6 4.2 1.3e-27 96.6 4.2 1.9 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain 7tm_2 PF00002.24 RUS84480.1 - 4.5e-53 180.0 27.6 6.2e-53 179.6 27.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS84480.1 - 1.1e-15 57.8 2.7 2.6e-15 56.7 2.7 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Saf_2TM PF18303.1 RUS84480.1 - 0.88 9.2 3.1 36 3.9 0.3 3.1 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DUF4293 PF14126.6 RUS84480.1 - 1.1 9.5 13.4 0.057 13.7 1.9 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4293) TORC_M PF12885.7 RUS84481.1 - 0.036 14.0 0.5 0.036 14.0 0.5 2.2 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain FA_desaturase PF00487.24 RUS84483.1 - 9.4 6.0 7.5 31 4.3 7.4 1.8 1 1 0 1 1 1 0 Fatty acid desaturase Fcf1 PF04900.12 RUS84484.1 - 6.8e-14 52.1 0.2 1.9e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Fcf1 Ank_2 PF12796.7 RUS84485.1 - 3.1e-46 155.9 6.0 6e-12 46.0 0.0 5.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.13 RUS84485.1 - 1.5e-45 153.3 19.3 7e-28 96.7 4.7 3.3 3 0 0 3 3 3 2 Mib_herc2 Ank_5 PF13857.6 RUS84485.1 - 2.6e-43 145.5 11.4 7.9e-10 38.8 0.1 7.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) SH3_15 PF18346.1 RUS84485.1 - 7.8e-41 138.2 11.9 1.7e-20 73.1 0.1 3.6 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_4 PF13637.6 RUS84485.1 - 1.5e-38 130.7 11.8 6.1e-11 42.6 0.3 7.3 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 RUS84485.1 - 1.1e-36 123.7 21.6 4.5e-07 30.0 0.2 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 RUS84485.1 - 5.3e-27 90.9 10.9 0.00048 20.4 0.0 10.2 10 0 0 10 10 9 7 Ankyrin repeat zf-C3HC4_3 PF13920.6 RUS84485.1 - 4.1e-19 68.2 30.7 7.9e-11 41.7 10.9 3.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 RUS84485.1 - 2.8e-10 39.9 7.7 2.8e-10 39.9 7.7 4.0 4 0 0 4 4 3 1 Zinc finger, ZZ type Prok-RING_4 PF14447.6 RUS84485.1 - 0.0092 15.8 11.2 0.0092 15.8 11.2 3.4 3 0 0 3 3 2 2 Prokaryotic RING finger family 4 DUF4314 PF14192.6 RUS84485.1 - 0.1 12.6 4.5 14 5.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) Spo0M PF07070.11 RUS84485.1 - 0.14 11.7 0.2 0.29 10.6 0.2 1.4 1 0 0 1 1 1 0 SpoOM protein FA_desaturase PF00487.24 RUS84487.1 - 0.17 11.7 15.1 0.22 11.3 15.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase MFS_1 PF07690.16 RUS84488.1 - 1e-34 120.0 51.2 9.6e-29 100.4 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5464 PF17552.2 RUS84488.1 - 0.44 10.9 6.9 1.3 9.4 1.5 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5464) SDF PF00375.18 RUS84489.1 - 1.5e-111 373.2 12.7 1.7e-111 373.0 12.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Fumarate_red_C PF02300.17 RUS84489.1 - 0.00032 20.8 1.1 0.066 13.3 0.1 2.5 2 0 0 2 2 2 2 Fumarate reductase subunit C GST_C_3 PF14497.6 RUS84491.1 - 1.4e-23 82.9 1.3 2.5e-23 82.1 1.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS84491.1 - 2.2e-12 47.1 0.0 4.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS84491.1 - 2.3e-11 43.8 0.4 3.4e-11 43.2 0.4 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS84491.1 - 8.3e-06 25.7 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS84491.1 - 0.00046 20.9 0.0 0.0098 16.6 0.0 2.3 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 RUS84491.1 - 0.00063 20.1 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS84491.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 RUS84491.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PLAC8 PF04749.17 RUS84492.1 - 1.1e-21 77.7 3.7 1.2e-21 77.5 3.7 1.0 1 0 0 1 1 1 1 PLAC8 family DUF1232 PF06803.12 RUS84492.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) GST_C_3 PF14497.6 RUS84493.1 - 4.7e-21 74.8 0.0 8.9e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS84493.1 - 6.4e-13 48.8 0.0 1.7e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS84493.1 - 6.7e-09 35.9 0.0 1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS84493.1 - 7.5e-05 23.1 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS84493.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS84493.1 - 0.0031 18.2 0.0 0.0055 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS84493.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS84493.1 - 0.056 13.8 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS84494.1 - 7.8e-24 83.8 0.1 1.4e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS84494.1 - 2.3e-11 43.9 0.0 9.6e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS84494.1 - 2.7e-09 37.1 0.1 5.1e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS84494.1 - 6.4e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RUS84494.1 - 0.0028 18.4 0.0 0.033 14.9 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 RUS84494.1 - 0.013 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS84494.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS84495.1 - 3.9e-22 78.3 0.5 6.5e-22 77.6 0.3 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS84495.1 - 7.5e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS84495.1 - 1.6e-08 34.7 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS84495.1 - 8.7e-06 26.1 0.0 3.1e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain CDC45 PF02724.14 RUS84495.1 - 0.0013 17.2 10.9 0.0013 17.1 10.9 1.2 1 0 0 1 1 1 1 CDC45-like protein GST_N_4 PF17172.4 RUS84495.1 - 0.025 15.3 0.0 0.046 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 RUS84495.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Vfa1 PF08432.10 RUS84495.1 - 0.047 14.0 0.5 0.047 14.0 0.5 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 M11L PF11099.8 RUS84495.1 - 0.05 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11L like GST_N_2 PF13409.6 RUS84495.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Nop14 PF04147.12 RUS84495.1 - 0.92 7.6 31.6 1.5 6.9 31.6 1.3 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS84495.1 - 5.4 5.2 11.8 8.4 4.6 11.7 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FERM_M PF00373.18 RUS84496.1 - 2.5e-21 76.2 0.1 2.5e-21 76.2 0.1 3.5 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 RUS84496.1 - 7.9e-14 51.8 0.1 7.9e-14 51.8 0.1 2.2 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 RUS84496.1 - 5.3e-12 45.5 0.1 1e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain DUF2428 PF10350.9 RUS84498.1 - 2.3e-49 168.1 0.2 2.3e-49 168.1 0.2 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 RUS84498.1 - 0.0024 18.0 0.6 3.1 8.3 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat BTB PF00651.31 RUS84499.1 - 9e-24 83.8 0.1 1.5e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS84499.1 - 0.0017 18.4 0.0 0.0083 16.2 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 RUS84499.1 - 0.014 15.6 0.5 0.025 14.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) RVT_1 PF00078.27 RUS84500.1 - 8.6e-36 123.5 0.0 1.5e-34 119.5 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS84500.1 - 5.2e-16 58.6 0.0 1.3e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cys_rich_FGFR PF00839.17 RUS84500.1 - 0.14 12.3 1.3 1 9.5 0.1 2.7 2 0 0 2 2 2 0 Cysteine rich repeat PHD PF00628.29 RUS84501.1 - 0.00016 21.5 6.3 0.00034 20.4 6.3 1.6 1 0 0 1 1 1 1 PHD-finger MscS_porin PF12795.7 RUS84501.1 - 0.0066 16.0 3.1 0.0066 16.0 3.1 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Arfaptin PF06456.13 RUS84501.1 - 0.02 14.4 2.8 0.038 13.5 2.8 1.4 1 0 0 1 1 1 0 Arfaptin-like domain SIMPL PF04402.14 RUS84501.1 - 0.069 13.6 2.8 0.43 11.0 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF541) DUF948 PF06103.11 RUS84501.1 - 1 9.7 6.9 0.74 10.1 4.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 RUS84501.1 - 1.5 8.9 6.9 1 9.4 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RRM_3 PF08777.11 RUS84501.1 - 3.6 7.7 9.3 0.24 11.4 0.5 3.0 2 1 1 3 3 3 0 RNA binding motif FlaC_arch PF05377.11 RUS84501.1 - 5.7 7.4 10.1 0.18 12.2 2.7 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PRORP PF16953.5 RUS84502.1 - 1.1e-50 172.4 0.2 2.2e-50 171.4 0.2 1.4 1 0 0 1 1 1 1 Protein-only RNase P Glyco_hydro_2_C PF02836.17 RUS84502.1 - 0.0013 17.9 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain RNase_Zc3h12a PF11977.8 RUS84502.1 - 0.004 17.0 0.0 0.043 13.6 0.0 2.3 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Lant_dehydr_C PF14028.6 RUS84502.1 - 0.018 14.6 0.8 0.033 13.7 0.1 1.7 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term HMGL-like PF00682.19 RUS84502.1 - 0.059 12.9 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 HMGL-like Flavodoxin_5 PF12724.7 RUS84502.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain DDE_Tnp_IS1595 PF12762.7 RUS84503.1 - 8.8e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Stirrup PF09061.6 RUS84503.1 - 0.11 12.8 0.0 0.7 10.1 0.0 2.1 1 1 1 2 2 2 0 Stirrup CdAMP_rec PF06153.11 RUS84503.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclic-di-AMP receptor Peptidase_M14 PF00246.24 RUS84504.1 - 1.5e-30 107.0 0.0 1.9e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Serglycin PF04360.12 RUS84505.1 - 2.7 7.9 4.6 0.95 9.4 0.3 2.1 2 0 0 2 2 2 0 Serglycin Rv2175c_C PF18367.1 RUS84507.1 - 0.035 14.2 0.2 9.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Rv2175c C-terminal domain of unknown function Furin-like_2 PF15913.5 RUS84508.1 - 1.6e-34 118.3 23.5 1.6e-34 118.3 23.5 2.4 3 0 0 3 3 3 1 Furin-like repeat, cysteine-rich Aa_trans PF01490.18 RUS84509.1 - 1.4e-84 284.2 32.3 6.3e-57 193.1 14.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein MtN3_slv PF03083.16 RUS84509.1 - 0.48 10.5 16.6 3.3 7.8 3.3 3.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange G-gamma PF00631.22 RUS84511.1 - 1.7e-14 53.5 0.1 2.1e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 GGL domain DUF1768 PF08719.11 RUS84512.1 - 5.2e-53 179.6 0.4 6.2e-53 179.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FERM_C PF09380.10 RUS84514.1 - 1.1e-20 73.8 0.0 2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS84514.1 - 3.3e-15 56.5 0.0 8.1e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS84514.1 - 1.3e-14 53.9 0.2 2.7e-14 52.8 0.2 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 RUS84514.1 - 7e-12 45.2 1.9 7e-12 45.2 1.9 2.1 2 0 0 2 2 2 1 FERM adjacent (FA) RWD PF05773.22 RUS84515.1 - 1.2e-18 67.4 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 RUS84515.1 - 0.0017 18.2 9.6 0.0041 16.9 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS84515.1 - 0.0019 18.2 8.9 0.0056 16.7 8.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS84515.1 - 0.0038 17.1 12.6 0.018 15.0 12.6 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS84515.1 - 0.0098 15.7 10.4 0.027 14.3 10.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS84515.1 - 0.092 13.1 15.8 0.042 14.2 12.6 2.1 2 0 0 2 2 2 0 Ring finger domain FYVE PF01363.21 RUS84515.1 - 2.1 8.5 10.9 4.3 7.5 10.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger Caveolin PF01146.17 RUS84516.1 - 0.00087 19.3 7.5 4 7.4 0.2 3.5 1 1 3 4 4 4 4 Caveolin AP4E_app_platf PF14807.6 RUS84516.1 - 0.0052 17.1 6.5 18 5.7 0.2 3.7 1 1 2 4 4 4 3 Adaptin AP4 complex epsilon appendage platform Ras PF00071.22 RUS84517.1 - 1.1e-22 80.3 0.4 4.4e-17 62.1 0.1 2.1 2 0 0 2 2 2 2 Ras family RsgA_GTPase PF03193.16 RUS84517.1 - 3.6e-07 30.2 2.1 0.00095 19.1 0.3 2.1 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 RUS84517.1 - 6e-06 26.5 0.1 0.002 18.3 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 RUS84517.1 - 0.0013 19.0 0.2 0.0069 16.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 RUS84517.1 - 0.0018 17.8 0.3 0.041 13.4 0.2 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 RUS84517.1 - 0.0021 18.5 0.2 0.0059 17.0 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RUS84517.1 - 0.028 15.0 0.2 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 RUS84517.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 RUS84517.1 - 0.063 13.2 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 RUS84517.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Gal_mutarotas_2 PF13802.6 RUS84519.1 - 2.5 8.5 8.3 27 5.2 1.7 4.3 1 1 2 3 3 3 0 Galactose mutarotase-like BING4CT PF08149.11 RUS84520.1 - 2.7e-07 30.3 0.3 3.2 7.6 0.1 4.2 1 1 2 3 3 3 3 BING4CT (NUC141) domain CEP76-C2 PF15627.6 RUS84520.1 - 0.4 10.2 2.3 46 3.5 0.1 3.1 1 1 3 4 4 4 0 CEP76 C2 domain SSF PF00474.17 RUS84521.1 - 2e-18 66.5 13.4 2e-18 66.5 13.4 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family CsoS2_M PF12288.8 RUS84522.1 - 1.1e-05 25.0 11.4 0.00023 20.7 10.3 2.1 1 1 1 2 2 2 2 Carboxysome shell peptide mid-region DUF2865 PF11064.8 RUS84522.1 - 0.00089 19.6 0.1 2.8 8.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2865) APC_u15 PF16636.5 RUS84522.1 - 0.023 15.1 28.0 4.9 7.6 1.3 4.8 1 1 4 5 5 5 0 Unstructured region on APC between APC_crr regions 5 and 6 TOM13 PF08219.11 RUS84522.1 - 0.026 14.5 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Outer membrane protein TOM13 AbiEii PF08843.11 RUS84522.1 - 0.041 13.8 0.2 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Opiods_neuropep PF01160.18 RUS84522.1 - 0.3 11.2 3.5 28 4.9 0.1 3.3 4 0 0 4 4 4 0 Vertebrate endogenous opioids neuropeptide ICAM_N PF03921.14 RUS84522.1 - 0.31 10.8 1.5 27 4.5 0.1 2.6 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain SSF PF00474.17 RUS84523.1 - 3.7e-42 144.6 24.0 5.1e-42 144.2 24.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family RNase_H PF00075.24 RUS84523.1 - 0.00079 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 RNase H PTPA PF03095.15 RUS84523.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF1943 PF09172.11 RUS84524.1 - 1.8e-05 24.2 29.0 0.00084 18.7 9.7 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF1943) Mucin-like PF16058.5 RUS84526.1 - 3.8 7.6 79.4 2.4 8.3 31.4 3.3 2 1 1 3 3 3 0 Mucin-like CheR_N PF03705.15 RUS84527.1 - 0.00021 21.0 55.1 11 5.8 0.3 12.1 1 1 11 12 12 12 12 CheR methyltransferase, all-alpha domain NDUFV3 PF15880.5 RUS84527.1 - 0.97 9.5 23.7 3.7e+02 1.2 0.0 10.5 11 0 0 11 11 11 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial DUF1064 PF06356.11 RUS84528.1 - 0.00011 22.6 3.4 13 6.2 3.4 4.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1064) RAWUL PF16207.5 RUS84528.1 - 0.0014 19.2 5.1 96 3.8 5.1 4.8 1 1 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Bactofilin PF04519.13 RUS84528.1 - 0.006 16.9 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 Polymer-forming cytoskeletal Qn_am_d_aII PF14930.6 RUS84528.1 - 0.027 14.8 6.1 0.44 10.9 6.1 2.5 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II TraF_2 PF13729.6 RUS84528.1 - 0.28 10.5 10.8 2.4e+02 0.9 10.8 2.8 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein TCRP1 PF14944.6 RUS84528.1 - 8.3 6.3 21.0 74 3.2 5.2 3.5 1 1 2 3 3 3 0 Tongue Cancer Chemotherapy Resistant Protein 1 Cwf_Cwc_15 PF04889.12 RUS84529.1 - 0.25 11.1 11.3 0.36 10.5 11.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 RUS84529.1 - 0.44 10.4 3.4 0.58 10.0 3.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Astro_capsid_p PF12226.8 RUS84529.1 - 0.56 9.3 14.7 0.77 8.9 14.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein IFT57 PF10498.9 RUS84529.1 - 0.93 8.4 2.8 1.3 7.9 2.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2457 PF10446.9 RUS84529.1 - 1.2 8.3 16.8 2 7.5 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Osteopontin PF00865.18 RUS84529.1 - 9.8 5.6 18.4 14 5.1 18.4 1.2 1 0 0 1 1 1 0 Osteopontin DUF3693 PF12472.8 RUS84530.1 - 0.00054 19.6 0.0 9 6.0 0.0 3.5 3 0 0 3 3 3 3 Phage related protein Dehydratase_hem PF13816.6 RUS84530.1 - 0.085 12.2 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Haem-containing dehydratase HflK_N PF12221.8 RUS84530.1 - 1.2 9.2 8.0 78 3.4 0.0 4.5 5 0 0 5 5 5 0 Bacterial membrane protein N terminal CSRNP_N PF16019.5 RUS84533.1 - 0.11 12.3 1.5 0.23 11.3 1.5 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF3827 PF12877.7 RUS84533.1 - 0.35 9.2 4.2 0.46 8.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PI3Ka PF00613.20 RUS84535.1 - 0.013 14.9 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 RUS84536.1 - 2.6e-14 53.4 0.2 4.2e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 C2 domain cPLA2_C2 PF18695.1 RUS84536.1 - 0.069 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain PLA2_B PF01735.18 RUS84537.1 - 1.9e-66 224.5 0.0 2.6e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain FOG_N PF15888.5 RUS84537.1 - 0.093 13.1 2.7 0.17 12.2 2.7 1.3 1 0 0 1 1 1 0 Folded gastrulation N-terminus Nop14 PF04147.12 RUS84537.1 - 0.19 9.9 6.5 0.26 9.4 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS84537.1 - 0.77 9.1 11.5 1.1 8.6 11.5 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 RUS84537.1 - 0.79 10.1 21.3 1.7 9.1 21.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RUS84537.1 - 0.99 9.1 5.7 1.7 8.3 5.7 1.3 1 0 0 1 1 1 0 FAM176 family Pes-10 PF07149.11 RUS84537.1 - 1.2 8.1 6.1 1.9 7.5 6.1 1.2 1 0 0 1 1 1 0 Pes-10 Utp14 PF04615.13 RUS84537.1 - 1.5 7.3 8.7 1.4 7.4 7.2 1.5 2 0 0 2 2 2 0 Utp14 protein Sporozoite_P67 PF05642.11 RUS84537.1 - 7.6 4.5 8.9 11 4.0 8.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 RUS84537.1 - 9 6.3 8.4 15 5.6 8.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Ig_2 PF13895.6 RUS84540.1 - 0.025 14.9 0.8 2 8.8 0.2 2.4 2 0 0 2 2 2 0 Immunoglobulin domain NOA36 PF06524.12 RUS84541.1 - 0.0058 16.0 23.9 0.012 14.9 23.9 1.6 1 0 0 1 1 1 1 NOA36 protein Synuclein PF01387.17 RUS84541.1 - 0.006 16.8 0.3 4.9 7.4 0.0 3.0 1 1 2 3 3 3 1 Synuclein Tom5 PF10642.9 RUS84541.1 - 0.014 15.4 10.1 5.2 7.2 0.2 6.4 1 1 6 8 8 8 0 Mitochondrial import receptor subunit or translocase BclA_C PF18573.1 RUS84541.1 - 0.026 14.4 8.7 67 3.4 0.1 6.3 1 1 8 9 9 9 0 BclA C-terminal domain DUF5470 PF17564.2 RUS84541.1 - 0.032 14.4 4.8 25 5.1 0.0 4.8 1 1 4 6 6 6 0 Family of unknown function (DUF5470) KMP11 PF03037.16 RUS84541.1 - 0.032 15.0 0.4 0.89 10.4 0.4 2.8 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 PCC_BT PF18140.1 RUS84541.1 - 0.082 13.3 0.0 1.6 9.1 0.0 2.6 1 1 2 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain TFIIA PF03153.13 RUS84541.1 - 0.31 11.0 18.3 0.37 10.7 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 RUS84541.1 - 0.66 9.1 12.7 0.87 8.7 12.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 RUS84541.1 - 0.73 8.0 19.5 0.96 7.6 19.5 1.0 1 0 0 1 1 1 0 Nop14-like family CssAB PF16831.5 RUS84541.1 - 0.74 10.2 15.9 15 6.0 0.4 4.5 1 1 3 4 4 4 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 RRN3 PF05327.11 RUS84541.1 - 6.6 5.2 20.8 9.6 4.6 20.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 RUS84541.1 - 9.6 5.9 12.4 18 5.0 12.4 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Hva1_TUDOR PF11160.8 RUS84543.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain CBM_1 PF00734.18 RUS84543.1 - 0.33 11.0 2.1 14 5.8 0.2 2.7 3 0 0 3 3 3 0 Fungal cellulose binding domain MFS_1 PF07690.16 RUS84545.1 - 6.9e-30 104.2 36.2 1.4e-21 76.8 21.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily rve PF00665.26 RUS84546.1 - 2.4e-08 34.2 0.0 5.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1759 PF03564.15 RUS84546.1 - 0.037 14.0 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) PNMA PF14893.6 RUS84546.1 - 0.042 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 PNMA MFS_1 PF07690.16 RUS84547.1 - 1.6e-31 109.6 15.9 5e-22 78.3 1.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily wnt PF00110.19 RUS84548.1 - 5.4e-102 341.5 20.9 6.2e-102 341.3 20.9 1.0 1 0 0 1 1 1 1 wnt family GTP_EFTU PF00009.27 RUS84549.1 - 1.2e-62 210.9 0.1 1.9e-62 210.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RUS84549.1 - 1.8e-34 118.1 0.0 3.7e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 RUS84549.1 - 2.4e-28 98.0 0.0 4.4e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 RUS84549.1 - 5.5e-18 65.1 0.5 1.5e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RUS84549.1 - 3.4e-05 23.7 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RUS84549.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RUS84549.1 - 0.0035 16.7 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AvrPtoB_bdg PF16847.5 RUS84549.1 - 0.01 16.3 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain DUF442 PF04273.13 RUS84549.1 - 0.059 13.5 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Sex_peptide PF08138.11 RUS84549.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family SRPRB PF09439.10 RUS84549.1 - 0.12 11.8 0.0 0.62 9.5 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Astacin PF01400.24 RUS84551.1 - 3e-56 190.1 0.7 3.9e-56 189.7 0.0 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 RUS84551.1 - 0.00064 19.6 1.3 0.067 13.0 0.4 2.6 1 1 0 2 2 2 2 Matrixin Methyltransf_2 PF00891.18 RUS84551.1 - 0.19 11.0 0.3 3.6 6.8 0.1 2.5 2 0 0 2 2 2 0 O-methyltransferase domain Reprolysin_4 PF13583.6 RUS84551.1 - 2 8.0 8.6 0.069 12.8 0.2 2.6 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like IMS_C PF11799.8 RUS84552.1 - 4.9e-09 36.9 0.0 0.34 11.6 0.0 4.9 1 1 0 2 2 2 2 impB/mucB/samB family C-terminal domain DUF4789 PF16033.5 RUS84552.1 - 1.9e-07 31.5 35.9 0.98 10.0 1.5 6.1 1 1 5 6 6 6 6 Domain of unknown function (DUF4789) ACBP PF00887.19 RUS84552.1 - 1.9e-06 28.0 4.9 20 5.5 0.0 5.5 1 1 5 6 6 6 4 Acyl CoA binding protein PemK_toxin PF02452.17 RUS84552.1 - 1.8e-05 25.1 0.0 13 6.2 0.0 4.7 4 1 1 5 5 5 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system PatG_C PF18065.1 RUS84552.1 - 0.0093 15.9 3.4 1.1e+02 2.7 0.0 5.0 5 1 1 6 6 6 0 PatG C-terminal zf-ANAPC11 PF12861.7 RUS84552.1 - 0.24 11.5 31.9 7.3 6.7 1.4 6.1 1 1 5 6 6 6 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.22 RUS84553.1 - 2.2e-14 53.0 0.0 3.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_2 PF13895.6 RUS84555.1 - 0.0012 19.2 0.7 0.0087 16.4 0.3 2.5 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 RUS84555.1 - 0.0033 18.0 0.4 0.17 12.5 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin domain HA1 PF18239.1 RUS84555.1 - 0.043 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Hemagglutinin I Lectin_C PF00059.21 RUS84556.1 - 2.8e-05 24.8 5.4 0.00083 20.1 0.6 2.2 2 0 0 2 2 2 2 Lectin C-type domain HAUS6_N PF14661.6 RUS84558.1 - 1.6e-47 162.0 6.3 1.6e-47 162.0 3.0 2.4 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF1640 PF07798.11 RUS84558.1 - 0.06 13.4 2.1 0.14 12.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Ccdc124 PF06244.12 RUS84559.1 - 1.6e-37 128.9 7.4 1.6e-37 128.9 7.4 2.4 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 RUS84559.1 - 0.00097 19.5 0.4 0.00097 19.5 0.4 3.3 2 1 0 2 2 2 1 HMG (high mobility group) box CoA_binding_3 PF13727.6 RUS84559.1 - 0.6 10.1 2.4 2.5 8.1 0.6 2.3 2 1 0 2 2 2 0 CoA-binding domain AAA_18 PF13238.6 RUS84560.1 - 5.5e-13 49.6 0.0 8.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 RUS84560.1 - 6.4e-05 22.8 0.1 0.19 11.5 0.1 2.4 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 RUS84560.1 - 0.0012 19.0 0.2 0.016 15.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RUS84560.1 - 0.0074 16.4 0.1 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 RUS84560.1 - 0.009 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.14 RUS84560.1 - 0.023 14.6 0.2 0.06 13.2 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 RUS84560.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS84560.1 - 0.07 13.5 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase CbiA PF01656.23 RUS84560.1 - 0.072 13.2 0.4 0.33 11.0 0.3 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CoaE PF01121.20 RUS84560.1 - 0.08 12.6 0.2 0.76 9.4 0.1 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_5 PF07728.14 RUS84560.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 RUS84560.1 - 0.14 12.1 0.1 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase LEM PF03020.15 RUS84561.1 - 1.2e-09 37.6 0.1 2.7e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 LEM domain adh_short_C2 PF13561.6 RUS84562.1 - 1.8e-45 155.4 0.4 2.3e-45 155.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS84562.1 - 5.2e-43 146.8 1.2 6.8e-43 146.4 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS84562.1 - 2.5e-08 34.0 1.2 3.6e-08 33.5 1.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS84562.1 - 0.021 14.1 0.1 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Enoyl_reductase PF12241.8 RUS84562.1 - 0.036 13.4 0.2 0.058 12.7 0.1 1.4 1 1 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region MORN_2 PF07661.13 RUS84563.1 - 0.093 13.0 4.7 4.7 7.8 0.8 3.2 1 1 3 4 4 4 0 MORN repeat variant DUF3579 PF12112.8 RUS84565.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) ABC_membrane PF00664.23 RUS84566.1 - 5.8e-43 147.5 5.8 6.9e-43 147.3 5.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region UPF0542 PF15086.6 RUS84566.1 - 0.095 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF4191 PF13829.6 RUS84566.1 - 1.1 8.5 3.9 1 8.6 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) ABC_tran PF00005.27 RUS84567.1 - 6.4e-20 72.1 0.2 3.1e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RUS84567.1 - 2.2e-06 27.3 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RUS84567.1 - 0.005 15.7 0.0 0.0069 15.2 0.0 1.3 1 1 0 1 1 1 1 Predicted ATPase of the ABC class KI67R PF08065.12 RUS84567.1 - 0.0053 17.3 2.1 0.0097 16.4 2.1 1.3 1 0 0 1 1 1 1 KI67R (NUC007) repeat SbcCD_C PF13558.6 RUS84567.1 - 0.032 14.5 0.8 0.5 10.6 0.8 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 RUS84568.1 - 1.3e-52 179.2 11.1 1.6e-52 178.8 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS84568.1 - 2.9e-36 125.0 0.1 4.6e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS84568.1 - 3e-08 33.4 0.5 2.6e-07 30.3 0.3 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RUS84568.1 - 6.7e-07 28.5 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 RUS84568.1 - 0.0008 19.7 0.1 0.0077 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS84568.1 - 0.0026 18.1 0.1 0.0088 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 RUS84568.1 - 0.026 13.8 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 RUS84568.1 - 0.029 14.3 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 RUS84568.1 - 0.034 14.1 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 RUS84568.1 - 0.081 13.4 0.2 1.2 9.5 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RUS84568.1 - 0.11 12.7 0.2 22 5.2 0.3 2.4 1 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RUS84568.1 - 0.12 12.7 3.8 0.34 11.2 0.8 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 RUS84568.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_membrane PF00664.23 RUS84570.1 - 4.6e-132 439.7 27.7 2.1e-69 234.2 8.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS84570.1 - 2.3e-75 251.6 0.3 3.1e-36 124.9 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS84570.1 - 3e-17 62.8 0.0 3.6e-07 29.8 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RUS84570.1 - 4.4e-09 35.7 0.7 1.2e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 RUS84570.1 - 4.3e-08 33.5 0.5 0.012 15.9 0.0 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RUS84570.1 - 3.3e-07 30.3 0.1 0.042 13.7 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 RUS84570.1 - 6.4e-07 29.9 2.8 0.042 14.2 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 RUS84570.1 - 1.7e-06 28.0 0.1 0.14 11.9 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 RUS84570.1 - 7.5e-06 25.4 0.5 0.044 13.1 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin Rad17 PF03215.15 RUS84570.1 - 9.2e-06 25.7 0.2 0.13 12.2 0.0 3.2 4 0 0 4 4 3 2 Rad17 P-loop domain AAA_5 PF07728.14 RUS84570.1 - 5.5e-05 23.2 0.1 0.44 10.5 0.0 3.7 3 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 RUS84570.1 - 6.7e-05 23.3 2.9 0.43 11.0 0.2 4.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 RUS84570.1 - 0.0001 22.0 0.7 0.53 10.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain G-alpha PF00503.20 RUS84570.1 - 0.00013 21.3 0.1 0.27 10.3 0.0 2.6 2 1 0 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 RUS84570.1 - 0.00028 20.2 0.0 0.18 11.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 RUS84570.1 - 0.00051 19.6 0.2 0.45 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 RUS84570.1 - 0.00079 19.6 2.8 0.32 11.1 0.0 3.5 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_30 PF13604.6 RUS84570.1 - 0.001 18.8 2.3 0.7 9.6 0.2 3.6 2 2 0 2 2 2 1 AAA domain PRK PF00485.18 RUS84570.1 - 0.0041 16.9 0.1 2.7 7.7 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 RUS84570.1 - 0.0044 17.3 1.2 13 6.0 0.0 3.7 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 RUS84570.1 - 0.0067 16.8 0.5 6.5 7.2 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 RUS84570.1 - 0.012 15.3 0.0 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RUS84570.1 - 0.016 15.4 10.4 0.93 9.8 0.5 4.4 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RUS84570.1 - 0.027 14.0 0.1 6.2 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 RUS84570.1 - 0.036 13.7 0.5 6 6.5 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 RUS84570.1 - 0.036 13.7 3.5 3.7 7.1 0.4 3.3 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 RUS84570.1 - 0.039 13.1 0.1 4.4 6.4 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 RUS84570.1 - 0.041 14.1 0.0 9.6 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS84570.1 - 0.067 13.1 0.1 14 5.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 RUS84570.1 - 0.097 12.4 1.0 16 5.2 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Spore_YhaL PF14147.6 RUS84570.1 - 0.11 12.2 5.6 4.3 7.1 0.1 4.0 3 0 0 3 3 3 0 Sporulation protein YhaL AIG1 PF04548.16 RUS84570.1 - 0.11 11.8 1.0 12 5.2 0.1 3.4 3 0 0 3 3 3 0 AIG1 family tRNA_lig_kinase PF08303.11 RUS84570.1 - 0.16 12.0 0.3 10 6.1 0.0 2.9 3 0 0 3 3 2 0 tRNA ligase kinase domain SANTA PF09133.10 RUS84570.1 - 0.28 11.7 3.7 8.2 7.0 0.1 3.4 3 0 0 3 3 3 0 SANTA (SANT Associated) AAA_10 PF12846.7 RUS84570.1 - 1.5 7.7 4.5 9.4 5.0 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain RRM_1 PF00076.22 RUS84571.1 - 9.1e-10 38.2 0.4 1.8e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T2SSppdC PF12528.8 RUS84572.1 - 2.9 8.7 7.3 0.4 11.5 2.7 1.9 2 0 0 2 2 2 0 Type II secretion prepilin peptidase dependent protein C YbjQ_1 PF01906.17 RUS84572.1 - 7.8 7.2 7.3 4.5 8.0 1.4 3.1 1 1 3 4 4 4 0 Putative heavy-metal-binding EXOSC1 PF10447.9 RUS84573.1 - 5.9e-17 62.3 2.8 1.6e-11 44.8 0.2 2.6 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 RUS84573.1 - 2.5e-06 27.2 0.0 7.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Lysyl_oxidase PF01186.17 RUS84574.1 - 4.1e-56 189.9 0.4 7.2e-56 189.1 0.4 1.4 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 RUS84574.1 - 3e-38 130.4 10.9 5.8e-21 74.9 0.1 3.1 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 RUS84574.1 - 2.4e-11 44.0 10.9 1.4e-05 25.6 0.1 3.3 4 0 0 4 4 4 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 RUS84574.1 - 0.0002 21.8 1.5 0.39 11.3 0.9 2.5 2 0 0 2 2 2 2 Hepsin, SRCR domain DUF4050 PF13259.6 RUS84574.1 - 0.15 12.4 2.3 0.25 11.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) FSA_C PF10479.9 RUS84574.1 - 0.47 8.5 9.2 0.66 8.0 9.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAM199X PF15814.5 RUS84574.1 - 1.7 7.6 6.3 3.6 6.5 6.3 1.5 1 0 0 1 1 1 0 Protein family FAM199X Mucin PF01456.17 RUS84574.1 - 8.2 6.4 24.4 2.2 8.2 21.4 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 RUS84576.1 - 1.9e-13 50.1 27.4 0.00037 20.8 0.5 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS84576.1 - 1.7e-08 34.5 12.6 2e-05 24.8 5.2 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RUS84576.1 - 4.4 7.4 13.4 1.1 9.4 2.8 3.3 2 1 1 3 3 3 0 Aberrant zinc-finger CAML PF14963.6 RUS84576.1 - 6.1 6.9 6.6 17 5.4 6.6 1.8 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MMR1 PF08505.10 RUS84576.1 - 9.9 6.4 29.4 0.5 10.6 18.7 3.0 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein ThiF PF00899.21 RUS84577.1 - 4.6e-52 176.8 1.1 3.1e-51 174.1 0.1 2.1 1 1 1 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.14 RUS84577.1 - 0.0031 17.1 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 RUS84577.1 - 0.0088 16.3 3.3 1.4 9.2 0.9 3.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain PHM7_cyt PF14703.6 RUS84577.1 - 0.12 12.6 2.0 0.14 12.4 0.4 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ApbA PF02558.16 RUS84577.1 - 0.18 11.5 0.1 0.48 10.1 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA G-gamma PF00631.22 RUS84577.1 - 1.7 8.7 4.3 4.4 7.4 4.3 1.7 1 0 0 1 1 1 0 GGL domain Cut12 PF11500.8 RUS84577.1 - 2.3 8.2 10.3 0.17 11.8 1.8 2.2 2 0 0 2 2 2 0 Spindle pole body formation-associated protein EF-hand_1 PF00036.32 RUS84578.1 - 1e-18 65.4 4.9 2.4e-06 26.7 0.0 3.6 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 RUS84578.1 - 3.6e-18 63.9 3.0 6.6e-07 28.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 RUS84578.1 - 6.8e-18 64.9 6.0 4.9e-10 39.7 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS84578.1 - 3.2e-13 48.5 5.3 0.00028 20.2 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS84578.1 - 3.8e-10 39.4 1.1 0.00013 21.7 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS84578.1 - 7.4e-08 32.7 2.0 1.3e-05 25.5 0.6 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RUS84578.1 - 6.5e-05 22.7 2.2 0.16 11.9 0.2 3.3 2 1 1 3 3 3 3 EF hand EF-hand_9 PF14658.6 RUS84578.1 - 8.2e-05 22.9 0.1 0.0024 18.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain Sigma70_r1_1 PF03979.14 RUS84578.1 - 0.018 15.1 0.7 1.4 9.0 0.2 2.5 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 EF-hand_14 PF17959.1 RUS84578.1 - 0.02 15.2 1.6 0.056 13.8 1.1 1.8 1 1 1 2 2 2 0 EF-hand domain Nefa_Nip30_N PF10187.9 RUS84578.1 - 0.023 15.0 4.8 0.6 10.5 3.7 3.1 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 ParD PF09386.10 RUS84578.1 - 0.051 14.0 1.2 1 9.8 0.0 2.4 2 1 0 2 2 2 0 Antitoxin ParD HCO3_cotransp PF00955.21 RUS84579.1 - 1.9e-207 690.1 9.8 2.7e-207 689.6 9.8 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 RUS84579.1 - 2e-47 162.3 0.0 3.8e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Nucleo_P87 PF07267.11 RUS84580.1 - 4.1 6.1 5.3 0.25 10.2 0.3 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 LpxD PF04613.14 RUS84581.1 - 6e-07 29.2 14.8 6.9 6.5 0.2 7.4 1 1 6 7 7 7 6 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD SET PF00856.28 RUS84583.1 - 2.1e-18 67.3 0.0 2.1e-18 67.3 0.0 3.5 3 2 0 4 4 4 1 SET domain AWS PF17907.1 RUS84583.1 - 1e-13 51.1 9.2 1e-13 51.1 9.2 1.9 2 0 0 2 2 2 1 AWS domain SRI PF08236.11 RUS84584.1 - 3.1e-26 91.4 5.0 4.5e-26 90.9 5.0 1.2 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 RUS84584.1 - 8.7e-07 28.9 0.3 1.6e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 WW domain OrfB_IS605 PF01385.19 RUS84584.1 - 0.016 15.4 0.7 0.029 14.6 0.7 1.5 1 1 0 1 1 1 0 Probable transposase Ras PF00071.22 RUS84585.1 - 2.3e-55 186.6 0.0 2.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS84585.1 - 5.4e-35 120.2 0.0 7.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS84585.1 - 8.4e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS84585.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS84585.1 - 0.00022 21.3 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS84585.1 - 0.00044 20.2 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS84585.1 - 0.0022 17.6 0.1 0.0037 16.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RUS84585.1 - 0.0035 17.8 0.1 0.0044 17.4 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS84585.1 - 0.038 14.3 0.0 0.51 10.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 RUS84585.1 - 0.059 13.4 0.0 0.096 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RUS84585.1 - 0.065 12.9 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain CNPase PF05881.12 RUS84586.1 - 1.1e-25 90.7 0.0 8.2e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_33 PF13671.6 RUS84586.1 - 2e-08 34.5 0.0 5.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RUS84586.1 - 0.00026 20.3 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 RUS84586.1 - 0.00035 20.1 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 RUS84586.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS84586.1 - 0.067 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 RUS84586.1 - 0.096 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 RUS84586.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 RUS84586.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lectin_C PF00059.21 RUS84588.1 - 5.6e-23 81.7 3.1 3.5e-14 53.4 0.8 2.2 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 RUS84589.1 - 3.9e-07 30.8 0.0 6.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain VPDSG-CTERM PF18205.1 RUS84589.1 - 1.3 8.9 4.7 2.1 8.3 4.7 1.3 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF1687 PF07955.11 RUS84590.1 - 0.093 13.2 5.5 2.9 8.4 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1687) Peptidase_C2 PF00648.21 RUS84592.1 - 4e-99 331.4 0.0 5.5e-99 330.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS84592.1 - 4.2e-41 140.5 0.1 8.2e-41 139.6 0.1 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 RUS84592.1 - 4.9e-10 38.5 1.1 0.00091 19.0 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RUS84592.1 - 1.4e-09 36.8 0.0 0.00097 18.5 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RUS84592.1 - 2.3e-08 33.7 1.0 0.0013 18.5 0.1 4.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 RUS84592.1 - 1.1e-06 29.0 7.6 0.00018 21.9 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS84592.1 - 0.00011 21.5 0.0 0.014 14.8 0.0 2.9 2 0 0 2 2 2 1 EF hand Peptidase_C2 PF00648.21 RUS84594.1 - 0.00059 19.0 0.1 0.00078 18.6 0.1 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 RUS84595.1 - 1.7e-125 418.0 0.1 2.5e-125 417.4 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS84595.1 - 8.4e-49 165.5 0.0 1.3e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 RUS84596.1 - 1.6e-120 401.7 0.1 2.3e-120 401.1 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS84596.1 - 4.8e-48 163.0 0.0 1.2e-47 161.8 0.0 1.7 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 RUS84596.1 - 1.2e-09 37.0 2.2 0.001 18.5 0.0 4.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 RUS84596.1 - 2e-07 30.4 6.3 5.9e-05 22.7 0.1 5.3 6 0 0 6 6 6 1 EF-hand domain EF-hand_7 PF13499.6 RUS84596.1 - 3.1e-07 30.8 1.6 0.069 13.6 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS84596.1 - 7.4e-06 25.7 0.3 0.0017 18.2 0.0 3.5 2 1 1 3 3 3 1 EF-hand domain pair Inositol_P PF00459.25 RUS84597.1 - 1.4e-52 178.9 0.2 1.9e-52 178.5 0.2 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 RUS84598.1 - 5.9e-13 48.8 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS84598.1 - 7.9e-10 38.5 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RUS84598.1 - 8.6e-09 34.9 0.0 0.058 13.7 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 RUS84598.1 - 0.00021 21.7 0.0 2.8 8.6 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 RUS84598.1 - 0.0012 17.5 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 RUS84598.1 - 0.0015 18.8 0.0 4.4 7.8 0.0 2.9 1 1 3 4 4 4 3 HEAT repeats Cnd1 PF12717.7 RUS84598.1 - 0.0055 16.8 0.0 0.14 12.2 0.0 2.6 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cep57_CLD_2 PF14197.6 RUS84599.1 - 0.0054 16.8 2.7 0.43 10.7 0.4 2.3 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 RUS84599.1 - 0.036 14.2 4.0 0.1 12.7 3.9 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 STAT_alpha PF01017.20 RUS84599.1 - 0.055 13.4 1.6 0.064 13.2 1.6 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain EzrA PF06160.12 RUS84599.1 - 0.075 11.2 4.9 0.55 8.3 0.2 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Ly49 PF08391.10 RUS84599.1 - 0.08 13.3 0.7 0.08 13.3 0.7 1.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Nas2_N PF18265.1 RUS84599.1 - 0.11 12.4 2.1 0.68 9.9 0.1 2.3 2 1 0 2 2 2 0 Nas2 N_terminal domain FlaC_arch PF05377.11 RUS84599.1 - 0.16 12.4 5.8 0.6 10.5 1.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 RUS84599.1 - 0.36 10.6 10.8 0.12 12.1 1.6 2.4 2 1 0 2 2 2 0 Septum formation initiator YgaB PF14182.6 RUS84599.1 - 0.77 10.2 4.8 3.6 8.1 1.2 2.3 2 0 0 2 2 2 0 YgaB-like protein Spc7 PF08317.11 RUS84599.1 - 0.88 8.4 7.2 2.5 6.9 0.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 RUS84599.1 - 1.1 9.2 7.4 2.7 8.0 0.2 2.6 2 1 1 3 3 3 0 Laminin Domain II YabA PF06156.13 RUS84599.1 - 2.8 8.6 5.1 10 6.8 1.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF5595 PF18077.1 RUS84599.1 - 2.8 8.1 9.4 7.3 6.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) GrpE PF01025.19 RUS84599.1 - 3.2 7.4 7.0 4.5 6.9 0.8 2.0 2 0 0 2 2 2 0 GrpE WHEP-TRS PF00458.20 RUS84600.1 - 4.9e-123 401.3 55.0 1.4e-22 79.6 4.5 6.9 6 0 0 6 6 6 6 WHEP-TRS domain tRNA-synt_1c PF00749.21 RUS84600.1 - 2.4e-107 358.5 3.3 4.5e-107 357.6 3.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RUS84600.1 - 5.4e-32 111.1 0.0 1.5e-31 109.6 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 RUS84600.1 - 5.2e-23 81.0 0.4 1.5e-22 79.5 0.4 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RUS84600.1 - 7.8e-18 65.1 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RUS84600.1 - 9e-18 64.2 0.0 2.8e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain DUF16 PF01519.16 RUS84600.1 - 6.2e-05 23.4 13.6 4.9 7.7 0.1 6.8 5 1 1 6 6 6 1 Protein of unknown function DUF16 GST_C_3 PF14497.6 RUS84600.1 - 7.4e-05 22.9 0.4 0.002 18.3 0.0 3.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS84600.1 - 0.00022 21.4 0.0 0.0011 19.1 0.0 2.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LRRNT_2 PF08263.12 RUS84600.1 - 0.0017 18.6 3.9 13 6.1 0.0 5.1 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain tRNA-synt_1e PF01406.19 RUS84600.1 - 0.0064 15.9 0.4 0.013 14.8 0.4 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PepSY_2 PF13670.6 RUS84600.1 - 0.11 12.5 36.7 0.3 11.1 0.7 5.9 6 0 0 6 6 6 0 Peptidase propeptide and YPEB domain RuvC PF02075.17 RUS84600.1 - 8.8 6.2 8.2 74 3.2 0.1 4.3 5 0 0 5 5 5 0 Crossover junction endodeoxyribonuclease RuvC RRM_1 PF00076.22 RUS84601.1 - 2e-10 40.3 0.0 2.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Branch PF02485.21 RUS84602.1 - 2.1e-28 99.5 0.5 2.1e-13 50.4 0.1 2.3 2 0 0 2 2 2 2 Core-2/I-Branching enzyme Branch PF02485.21 RUS84603.1 - 6.4e-30 104.5 0.1 7.3e-15 55.1 0.1 2.5 2 0 0 2 2 2 2 Core-2/I-Branching enzyme DUF5341 PF17276.2 RUS84603.1 - 0.019 15.2 0.3 0.043 14.0 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5341) Val_tRNA-synt_C PF10458.9 RUS84603.1 - 0.12 12.7 1.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm TFR_dimer PF04253.15 RUS84604.1 - 1.7e-22 79.7 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 RUS84604.1 - 2.3e-20 73.1 0.0 4.3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RUS84604.1 - 3.1e-10 39.9 0.0 9.2e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 RUS84604.1 - 0.022 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Paramyxo_C PF01692.18 RUS84604.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Nicastrin PF05450.15 RUS84604.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin EF-hand_1 PF00036.32 RUS84605.1 - 2.8e-35 117.2 8.1 3.2e-08 32.5 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS84605.1 - 4.4e-31 107.1 0.8 2.1e-16 60.1 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS84605.1 - 1.4e-27 93.2 2.2 5.6e-08 32.1 0.2 4.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RUS84605.1 - 2.2e-25 88.3 7.5 6.2e-14 51.6 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RUS84605.1 - 3e-24 83.4 4.5 2e-07 30.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RUS84605.1 - 1.6e-07 31.5 0.1 0.0029 17.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS84605.1 - 1.2e-06 28.8 0.0 0.053 13.8 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS84605.1 - 0.00083 19.3 0.3 0.046 13.7 0.1 2.3 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS84605.1 - 0.00096 19.1 0.3 3.7 7.4 0.0 3.2 2 2 1 3 3 3 2 Caleosin related protein UPF0154 PF03672.13 RUS84605.1 - 0.0038 17.2 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RUS84605.1 - 0.014 16.3 0.0 1.8 9.5 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain eIF3_subunit PF08597.10 RUS84605.1 - 0.018 15.0 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Dockerin_1 PF00404.18 RUS84605.1 - 0.025 14.7 6.1 7.3 6.9 0.6 3.5 1 1 3 4 4 4 0 Dockerin type I domain EFhand_Ca_insen PF08726.10 RUS84605.1 - 0.048 13.8 0.1 0.15 12.1 0.1 1.9 1 1 0 1 1 1 0 Ca2+ insensitive EF hand Phage_TAC_12 PF12363.8 RUS84605.1 - 0.064 13.7 0.4 1.8 9.0 0.1 2.3 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC GF_recep_IV PF14843.6 RUS84606.1 - 0.012 15.5 3.4 0.012 15.5 3.4 1.5 2 0 0 2 2 2 0 Growth factor receptor domain IV 7tm_1 PF00001.21 RUS84606.1 - 0.013 14.9 4.2 0.018 14.3 4.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ldl_recept_a PF00057.18 RUS84606.1 - 0.38 11.0 28.1 0.12 12.6 8.6 3.3 4 1 0 4 4 4 0 Low-density lipoprotein receptor domain class A IP_trans PF02121.18 RUS84607.1 - 2.5e-78 263.1 0.0 2.8e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein UPF0669 PF17065.5 RUS84608.1 - 9.8e-31 106.9 0.4 5.5e-30 104.5 0.4 1.8 1 1 0 1 1 1 1 Putative cytokine, C6ORF120 TPR_1 PF00515.28 RUS84609.1 - 5.8e-39 130.4 21.7 2.2e-08 33.6 0.3 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 RUS84609.1 - 2e-30 102.4 18.3 2.1e-06 27.4 0.1 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 RUS84609.1 - 3.5e-26 90.6 15.1 2.2e-10 40.1 0.6 5.6 5 1 0 5 5 5 3 TPR repeat TPR_8 PF13181.6 RUS84609.1 - 1.2e-21 75.1 16.6 0.00018 21.5 0.7 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 RUS84609.1 - 2.7e-17 62.8 4.3 2.4e-07 30.9 0.0 5.5 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS84609.1 - 5.2e-17 62.2 0.1 1.2e-05 25.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS84609.1 - 1.7e-16 60.5 6.8 8.9e-05 22.9 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat STI1 PF17830.1 RUS84609.1 - 5.4e-16 58.3 5.8 5.4e-16 58.3 5.8 2.8 3 0 0 3 3 2 1 STI1 domain TPR_17 PF13431.6 RUS84609.1 - 8.4e-16 57.1 3.4 0.00065 19.9 0.1 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS84609.1 - 7.7e-15 54.3 0.5 0.044 14.6 0.0 6.3 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 RUS84609.1 - 4.2e-09 36.4 0.0 0.24 11.6 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS84609.1 - 1.4e-07 31.0 4.3 0.042 13.9 0.0 5.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS84609.1 - 6.6e-06 26.4 7.7 0.71 10.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 RUS84609.1 - 1.6e-05 24.0 3.6 0.48 9.3 0.0 3.2 1 1 1 3 3 3 3 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 RUS84609.1 - 8.8e-05 22.3 5.6 1.7 8.7 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 RUS84609.1 - 0.00031 20.5 11.5 0.64 9.7 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 RUS84609.1 - 0.0088 15.5 0.0 0.041 13.3 0.0 2.0 1 1 1 2 2 2 1 MalT-like TPR region hnRNP_Q_AcD PF18360.1 RUS84609.1 - 0.019 14.9 0.2 0.4 10.7 0.1 2.7 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF5588 PF17826.1 RUS84609.1 - 0.025 13.5 0.5 0.47 9.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5588) ESCRT-II PF05871.12 RUS84609.1 - 0.053 13.8 0.4 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 ESCRT-II complex subunit Fis1_TPR_C PF14853.6 RUS84609.1 - 0.15 12.1 7.7 7.4 6.7 0.0 4.8 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Nodulin_late PF07127.11 RUS84610.1 - 3.6 8.0 6.8 0.33 11.3 1.0 2.2 2 0 0 2 2 2 0 Late nodulin protein RNase_H PF00075.24 RUS84611.1 - 0.0026 17.9 0.0 0.0096 16.1 0.0 2.0 3 0 0 3 3 3 1 RNase H PX PF00787.24 RUS84612.1 - 4.3e-28 97.6 0.0 5.4e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 PX domain DUF4061 PF13270.6 RUS84613.1 - 2.5e-30 104.6 2.4 4.2e-30 103.9 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF812 PF05667.11 RUS84613.1 - 0.0052 15.7 1.7 0.0054 15.7 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1515 PF07439.11 RUS84613.1 - 0.02 14.9 4.3 0.041 13.9 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF2937 PF11157.8 RUS84613.1 - 0.061 13.0 0.8 0.087 12.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4254 PF14063.6 RUS84613.1 - 0.2 11.4 4.6 0.23 11.3 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4254) fn3 PF00041.21 RUS84614.1 - 6.4e-05 23.2 0.0 0.00052 20.3 0.0 2.7 1 1 0 1 1 1 1 Fibronectin type III domain IQ PF00612.27 RUS84614.1 - 7.3e-05 22.2 0.3 0.00018 21.0 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_4 PF12799.7 RUS84615.1 - 3.2e-20 71.9 30.3 4.9e-08 33.1 2.7 4.3 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS84615.1 - 2.1e-18 66.4 11.1 9.6e-14 51.3 3.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RUS84615.1 - 2.5e-14 52.8 29.2 7e-07 28.9 2.0 4.5 2 1 1 4 4 4 4 Leucine rich repeat Glyco_hydro_49 PF03718.13 RUS84615.1 - 0.063 13.3 0.9 1.6 8.7 0.1 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 49 LRR_6 PF13516.6 RUS84615.1 - 0.074 13.1 25.4 1.6 8.9 0.4 6.7 6 1 1 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 RUS84615.1 - 0.1 13.2 29.2 27 5.9 0.2 8.0 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_2 PF07723.13 RUS84615.1 - 0.11 13.3 3.9 13 6.6 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat PHD PF00628.29 RUS84616.1 - 0.00038 20.3 15.8 0.00092 19.1 15.7 1.8 1 1 0 1 1 1 1 PHD-finger NIR_SIR_ferr PF03460.17 RUS84616.1 - 0.023 14.5 0.1 0.2 11.6 0.1 2.3 1 1 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain C1_1 PF00130.22 RUS84616.1 - 0.18 11.7 8.9 0.47 10.4 8.9 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_3 PF08777.11 RUS84616.1 - 0.18 11.9 3.5 0.19 11.8 0.8 2.5 2 1 0 2 2 2 0 RNA binding motif DUF3293 PF11697.8 RUS84616.1 - 0.94 10.0 6.3 22 5.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3293) Ribosomal_L24e PF01246.20 RUS84617.1 - 3.1e-32 110.6 1.6 3.1e-32 110.6 1.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L24e DUF676 PF05057.14 RUS84618.1 - 1.4e-53 181.6 0.0 2.3e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 RUS84618.1 - 5.1e-14 52.6 0.1 2e-13 50.7 0.1 2.1 1 0 0 1 1 1 1 Protein FAM135 Palm_thioest PF02089.15 RUS84618.1 - 7.6e-08 32.5 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 RUS84618.1 - 7.4e-05 22.6 0.1 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 RUS84618.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Nucleo_P87 PF07267.11 RUS84618.1 - 0.059 12.2 4.4 0.11 11.4 4.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Actin PF00022.19 RUS84619.1 - 4.2e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin PAP2 PF01569.21 RUS84620.1 - 2.5e-27 95.3 2.3 4.7e-27 94.4 2.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RUS84620.1 - 3.3e-05 23.6 1.1 6.6e-05 22.7 1.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 RUS84620.1 - 0.0012 19.3 2.0 0.0012 19.3 2.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Galactosyl_T PF01762.21 RUS84621.1 - 3.3e-35 121.7 0.0 4.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase VWA PF00092.28 RUS84625.1 - 2.2e-34 119.2 0.0 3.7e-24 85.9 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS84625.1 - 2e-14 54.1 0.1 6.3e-10 39.7 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 RUS84625.1 - 0.0044 17.0 0.4 1.4 8.9 0.1 2.9 2 1 0 2 2 2 2 von Willebrand factor type A domain Tudor_2 PF18104.1 RUS84626.1 - 8.9e-07 28.5 0.1 2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PHD PF00628.29 RUS84626.1 - 5.9e-06 26.1 39.6 0.00056 19.7 6.6 3.5 3 0 0 3 3 3 2 PHD-finger Mtf2_C PF14061.6 RUS84626.1 - 0.02 15.1 0.1 0.048 13.8 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 LBR_tudor PF09465.10 RUS84626.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain ADK PF00406.22 RUS84627.1 - 4.8e-48 163.1 0.0 8.4e-30 103.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 RUS84627.1 - 7e-19 68.6 0.0 3.4e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RUS84627.1 - 6.9e-09 36.3 0.0 0.00033 21.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 RUS84627.1 - 5.7e-08 33.3 1.7 0.2 11.9 0.2 3.9 3 1 1 4 4 4 3 Hydin Adenylate kinase-like domain DUF5582 PF17819.1 RUS84627.1 - 5.3e-05 23.7 0.1 0.00011 22.7 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5582) SKI PF01202.22 RUS84627.1 - 0.00092 19.4 0.1 0.11 12.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase Thymidylate_kin PF02223.17 RUS84627.1 - 0.0064 16.2 0.0 2.9 7.5 0.0 3.5 3 0 0 3 3 3 1 Thymidylate kinase AAA_33 PF13671.6 RUS84627.1 - 0.013 15.7 0.2 0.49 10.5 0.0 3.0 2 2 0 2 2 2 0 AAA domain Methyltransf_8 PF05148.15 RUS84627.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Sigma54_activat PF00158.26 RUS84627.1 - 0.087 12.5 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF5586 PF17824.1 RUS84627.1 - 0.094 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) AAA PF00004.29 RUS84627.1 - 0.13 12.7 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Proteasom_PSMB PF10508.9 RUS84628.1 - 2.4e-109 366.1 0.0 2.8e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 RUS84628.1 - 2.2e-05 24.6 0.0 0.1 12.8 0.0 3.9 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 RTTN_N PF14726.6 RUS84628.1 - 0.069 14.0 0.3 4.9 8.0 0.0 3.7 3 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning HEAT_2 PF13646.6 RUS84628.1 - 0.39 11.1 9.3 8.3 6.9 0.4 4.9 4 1 1 5 5 5 0 HEAT repeats WD40 PF00400.32 RUS84629.1 - 2.5e-34 116.7 17.5 6e-09 36.4 0.7 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS84629.1 - 0.00019 21.6 0.1 0.84 10.0 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS84629.1 - 0.0036 16.3 0.4 0.71 8.8 0.4 2.4 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AsnC_trans_reg PF01037.21 RUS84629.1 - 0.11 12.5 0.0 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain Nup160 PF11715.8 RUS84629.1 - 0.17 10.5 4.0 0.95 8.0 0.0 3.3 2 1 1 4 4 4 0 Nucleoporin Nup120/160 SSF PF00474.17 RUS84630.1 - 2.3e-201 669.0 20.1 8.9e-113 377.2 6.3 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family PAN_1 PF00024.26 RUS84630.1 - 0.076 13.0 0.4 18 5.4 0.1 2.4 2 0 0 2 2 2 0 PAN domain BCMA-Tall_bind PF09257.10 RUS84630.1 - 0.7 10.0 5.5 13 6.0 0.5 2.5 2 0 0 2 2 2 0 BCMA, TALL-1 binding Toxin_2 PF00451.19 RUS84630.1 - 5.4 7.4 11.9 14 6.1 2.3 2.5 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 PTPA PF03095.15 RUS84631.1 - 4.7e-116 387.5 0.0 5.6e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cornifin PF02389.15 RUS84632.1 - 3.8e-07 30.4 0.7 4.7e-07 30.1 0.7 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family zf-primase PF09329.11 RUS84632.1 - 0.0018 18.0 35.4 1.2 9.0 1.3 7.2 1 1 4 5 5 5 4 Primase zinc finger DUF1857 PF08982.11 RUS84632.1 - 0.0021 17.9 0.4 0.049 13.5 0.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1857) PulA_N1 PF17999.1 RUS84632.1 - 0.0093 16.7 7.3 0.67 10.7 0.1 2.7 1 1 1 2 2 2 2 Pullulanase N1-terminal domain Churchill PF06573.11 RUS84633.1 - 0.08 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Churchill protein DUF4744 PF15918.5 RUS84633.1 - 0.16 12.8 13.7 1.7 9.6 7.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) DUF2358 PF10184.9 RUS84634.1 - 1.9e-05 24.9 0.0 4.5 7.6 0.0 4.7 1 1 5 6 6 6 2 Uncharacterized conserved protein (DUF2358) INCENP_ARK-bind PF03941.15 RUS84634.1 - 2.2 8.3 17.1 17 5.5 0.4 4.8 2 1 5 7 7 7 0 Inner centromere protein, ARK binding region B9-C2 PF07162.11 RUS84635.1 - 0.075 13.2 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein 7tm_1 PF00001.21 RUS84636.1 - 6.6e-22 78.1 4.8 8.4e-22 77.7 4.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84636.1 - 1.3e-05 24.8 1.0 1.5e-05 24.5 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx STE3 PF02076.15 RUS84636.1 - 0.0011 18.2 0.5 0.0015 17.9 0.5 1.2 1 0 0 1 1 1 1 Pheromone A receptor DUF3099 PF11298.8 RUS84636.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF3262 PF11660.8 RUS84636.1 - 0.12 12.8 0.6 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) NicO PF03824.16 RUS84636.1 - 0.14 11.4 2.4 0.27 10.5 0.9 1.9 2 0 0 2 2 2 0 High-affinity nickel-transport protein MFS_1 PF07690.16 RUS84636.1 - 0.15 11.0 0.2 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.16 RUS84636.1 - 2.3 7.9 8.8 13 5.5 8.0 2.4 2 1 0 2 2 2 0 TLC domain Na_Ca_ex PF01699.24 RUS84637.1 - 1.5e-24 86.7 18.1 2e-24 86.3 18.1 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein SPC25 PF06703.11 RUS84638.1 - 0.054 13.3 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PAS_7 PF12860.7 RUS84638.1 - 0.079 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 PAS fold Na_Ca_ex PF01699.24 RUS84638.1 - 0.88 9.5 5.1 1.3 9.0 5.1 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 RUS84639.1 - 9.9e-06 25.6 1.2 1.9e-05 24.6 0.4 1.7 2 0 0 2 2 2 1 Sodium/calcium exchanger protein SRR1 PF07985.12 RUS84641.1 - 0.0093 16.0 0.2 0.088 12.9 0.1 2.4 2 0 0 2 2 2 1 SRR1 Kinesin PF00225.23 RUS84642.1 - 8.6e-50 169.5 0.2 9.6e-50 169.4 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain SSF PF00474.17 RUS84643.1 - 0.00085 18.3 2.9 0.00085 18.3 2.9 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family PspB PF06667.12 RUS84643.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B LEA_2 PF03168.13 RUS84644.1 - 5.4e-05 23.7 0.2 4 8.0 0.0 4.3 1 1 3 4 4 4 1 Late embryogenesis abundant protein DUF4832 PF16116.5 RUS84644.1 - 0.00079 19.3 3.0 0.4 10.5 0.7 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4832) Syntaxin-5_N PF11416.8 RUS84644.1 - 0.0024 17.1 0.0 3.7e+02 0.5 0.0 6.6 8 0 0 8 8 8 0 Syntaxin-5 N-terminal, Sly1p-binding domain CS PF04969.16 RUS84644.1 - 0.0035 18.3 12.6 30 5.7 0.6 5.1 1 1 1 2 2 2 0 CS domain ITI_HC_C PF06668.12 RUS84644.1 - 0.0036 17.0 7.5 0.16 11.6 1.1 2.9 1 1 2 3 3 3 2 Inter-alpha-trypsin inhibitor heavy chain C-terminus TEP1_N PF05386.11 RUS84644.1 - 0.0052 16.3 4.2 99 2.6 0.0 6.5 3 3 3 6 6 6 0 TEP1 N-terminal domain DUF4968 PF16338.5 RUS84644.1 - 0.0059 16.9 8.4 0.16 12.3 3.9 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4968) IL1 PF00340.19 RUS84644.1 - 0.015 14.9 13.2 1.6 8.4 0.7 4.1 1 1 3 4 4 4 0 Interleukin-1 / 18 Laminin_G_2 PF02210.24 RUS84644.1 - 0.022 15.3 0.3 9 6.9 0.1 2.6 1 1 1 2 2 2 0 Laminin G domain FucT_N PF18025.1 RUS84644.1 - 0.028 14.9 0.6 5.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain DUF3786 PF12654.7 RUS84644.1 - 0.078 12.6 3.4 1.4 8.5 0.4 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3786) APC_15aa PF05972.11 RUS84644.1 - 0.12 12.7 27.2 2 8.9 0.0 8.7 9 0 0 9 9 9 0 APC 15 residue motif VWD PF00094.25 RUS84644.1 - 0.14 12.4 2.9 6.5 7.0 2.8 2.3 1 1 0 1 1 1 0 von Willebrand factor type D domain CAMSAP_CH PF11971.8 RUS84644.1 - 0.19 11.6 1.5 10 6.0 0.2 3.0 2 2 0 2 2 2 0 CAMSAP CH domain Herpes_PAP PF03325.13 RUS84644.1 - 0.31 10.6 4.0 6.5 6.3 0.3 2.6 2 1 1 3 3 3 0 Herpesvirus polymerase accessory protein DUF4889 PF16230.5 RUS84644.1 - 0.63 10.3 9.2 5.2 7.4 2.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4889) HNH_4 PF13395.6 RUS84644.1 - 0.83 9.6 9.3 38 4.3 1.1 4.6 2 2 0 2 2 2 0 HNH endonuclease DUF4809 PF16067.5 RUS84644.1 - 1.8 8.7 9.2 1.7 8.8 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4809) CCDC23 PF15674.5 RUS84645.1 - 4.9e-11 42.5 8.2 1.9e-10 40.6 8.2 2.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 SID-1_RNA_chan PF13965.6 RUS84645.1 - 9.7 4.5 7.1 0.88 7.9 0.7 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PI3Ka PF00613.20 RUS84646.1 - 7.6e-46 155.8 8.3 1.8e-45 154.6 8.3 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 RUS84646.1 - 1.8e-19 69.2 0.1 6e-19 67.6 0.1 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 RUS84646.1 - 2.6e-16 59.7 1.5 3.9e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF2672 PF10878.8 RUS84646.1 - 0.0086 16.0 0.2 0.03 14.3 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2672) PI3K_C2 PF00792.24 RUS84646.1 - 0.044 13.7 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 Phosphoinositide 3-kinase C2 ArgoMid PF16487.5 RUS84646.1 - 0.095 13.0 0.1 6.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Mid domain of argonaute PI3_PI4_kinase PF00454.27 RUS84647.1 - 4e-56 190.6 2.2 2.5e-54 184.7 2.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 RUS84647.1 - 0.00062 19.2 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Transglut_core PF01841.19 RUS84648.1 - 4.1e-05 24.0 0.0 7.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF229 PF02995.17 RUS84649.1 - 1.1e-74 251.9 0.0 1.4e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS84649.1 - 3.3e-06 26.7 0.2 0.00031 20.3 0.0 2.2 1 1 0 2 2 2 2 Sulfatase EGF_3 PF12947.7 RUS84650.1 - 1.6e-23 82.6 83.4 2.5e-08 34.0 13.6 6.4 6 0 0 6 6 6 5 EGF domain EGF_CA PF07645.15 RUS84650.1 - 1.9e-14 53.6 29.5 7.3e-10 38.9 12.6 7.0 6 2 0 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 RUS84650.1 - 8.5e-09 35.2 30.9 8.6e-07 28.8 4.5 6.7 7 0 0 7 7 7 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 RUS84650.1 - 9.5e-07 28.8 7.5 9.5e-07 28.8 7.5 6.1 6 0 0 6 6 6 3 MSP1 EGF domain 1 EGF PF00008.27 RUS84650.1 - 3.8e-05 23.9 6.5 3.8e-05 23.9 6.5 7.9 6 2 0 7 7 7 4 EGF-like domain hEGF PF12661.7 RUS84650.1 - 0.0058 17.2 5.9 0.0058 17.2 5.9 7.7 7 0 0 7 7 7 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS84650.1 - 0.0077 16.6 12.5 0.0077 16.6 12.5 6.7 4 2 1 5 5 5 2 EGF-like domain FXa_inhibition PF14670.6 RUS84650.1 - 0.025 14.8 10.2 0.025 14.8 10.2 6.1 4 2 2 6 6 6 0 Coagulation Factor Xa inhibitory site RXT2_N PF08595.11 RUS84650.1 - 0.73 9.8 2.8 0.97 9.4 2.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Fibrinogen_C PF00147.18 RUS84651.1 - 0.0032 17.3 0.0 0.37 10.6 0.0 2.3 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_CA PF07645.15 RUS84652.1 - 4.2e-22 78.1 48.9 1.6e-10 41.0 7.3 5.7 6 0 0 6 6 6 3 Calcium-binding EGF domain cEGF PF12662.7 RUS84652.1 - 1.1e-14 54.1 18.4 1.2e-05 25.1 2.7 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS84652.1 - 1.9e-14 53.5 30.5 3.3e-09 36.8 6.6 5.8 6 0 0 6 6 6 3 EGF domain EGF PF00008.27 RUS84652.1 - 1.5e-06 28.4 29.7 9.4e-05 22.6 4.4 5.7 7 0 0 7 7 7 3 EGF-like domain hEGF PF12661.7 RUS84652.1 - 8.2e-05 23.1 40.1 0.0072 16.9 0.9 6.0 6 0 0 6 6 6 3 Human growth factor-like EGF VWD PF00094.25 RUS84653.1 - 4.3e-15 56.3 0.1 4.3e-15 56.3 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_CA PF07645.15 RUS84653.1 - 2.9e-14 53.0 27.3 1e-08 35.2 6.7 7.8 7 1 1 8 8 8 3 Calcium-binding EGF domain TIL PF01826.17 RUS84653.1 - 7.9e-10 38.8 9.3 7.9e-10 38.8 9.3 8.2 5 2 2 7 7 7 1 Trypsin Inhibitor like cysteine rich domain Kazal_2 PF07648.15 RUS84653.1 - 7e-08 32.5 21.3 1.2e-07 31.7 4.0 4.7 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain cEGF PF12662.7 RUS84653.1 - 1.5e-06 28.0 3.1 1.5e-06 28.0 3.1 7.5 8 0 0 8 8 8 3 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS84653.1 - 6.8e-05 23.0 26.1 0.0012 19.0 7.3 7.3 4 2 2 6 6 6 2 EGF domain EGF PF00008.27 RUS84653.1 - 0.00066 19.9 7.6 0.00066 19.9 7.6 8.8 8 3 1 9 9 9 2 EGF-like domain FXa_inhibition PF14670.6 RUS84653.1 - 0.0033 17.7 7.5 0.0033 17.7 7.5 8.3 5 3 2 7 7 7 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 RUS84653.1 - 0.0047 17.5 6.7 0.0047 17.5 6.7 9.0 9 0 0 9 9 9 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 RUS84653.1 - 0.021 14.9 0.9 0.021 14.9 0.9 6.4 6 0 0 6 6 6 0 MSP1 EGF domain 1 Kazal_2 PF07648.15 RUS84654.1 - 5.2e-07 29.7 3.0 5.2e-07 29.7 3.0 3.3 3 2 0 3 3 3 1 Kazal-type serine protease inhibitor domain EGF_CA PF07645.15 RUS84655.1 - 1.1e-15 57.6 27.6 1e-09 38.4 7.9 11.3 12 2 1 13 13 13 3 Calcium-binding EGF domain Kazal_2 PF07648.15 RUS84655.1 - 8.4e-10 38.6 15.2 1.5e-06 28.3 6.1 6.9 7 0 0 7 7 7 3 Kazal-type serine protease inhibitor domain TIL PF01826.17 RUS84655.1 - 8.7e-10 38.7 11.1 8.7e-10 38.7 11.1 11.4 9 3 2 11 11 11 1 Trypsin Inhibitor like cysteine rich domain cEGF PF12662.7 RUS84655.1 - 3.4e-05 23.7 2.9 3.4e-05 23.7 2.9 8.4 8 0 0 8 8 8 4 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS84655.1 - 0.012 15.8 7.5 0.012 15.8 7.5 10.4 8 3 2 10 10 10 0 EGF domain Fibrinogen_C PF00147.18 RUS84657.1 - 0.023 14.5 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_3 PF12947.7 RUS84658.1 - 2.3e-20 72.5 86.4 2.9e-08 33.8 6.2 6.6 7 0 0 7 7 7 5 EGF domain EGF_CA PF07645.15 RUS84658.1 - 1.6e-14 53.8 30.4 9.2e-10 38.6 12.0 7.6 6 2 1 7 7 7 2 Calcium-binding EGF domain cEGF PF12662.7 RUS84658.1 - 2.3e-10 40.2 16.7 1.3e-06 28.2 2.8 7.6 9 0 0 9 9 9 4 Complement Clr-like EGF-like EGF PF00008.27 RUS84658.1 - 5.3e-07 29.8 63.6 0.0002 21.6 4.9 7.8 6 3 1 7 7 7 4 EGF-like domain EGF_MSP1_1 PF12946.7 RUS84658.1 - 1.6e-06 28.0 58.4 3.5e-06 27.0 7.7 5.9 5 0 0 5 5 5 3 MSP1 EGF domain 1 EGF_2 PF07974.13 RUS84658.1 - 0.55 10.7 67.1 0.2 12.1 11.4 6.3 4 1 1 5 5 5 0 EGF-like domain Peptidase_C1 PF00112.23 RUS84659.1 - 1.7e-86 289.8 2.5 2e-86 289.6 2.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 RUS84659.1 - 6.9e-05 21.8 2.1 0.11 11.2 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-C3Hc3H PF13891.6 RUS84660.1 - 2.8e-28 98.1 19.6 6.2e-15 55.3 8.7 2.4 2 0 0 2 2 2 2 Potential DNA-binding domain Menin PF05053.13 RUS84660.1 - 0.82 8.0 14.3 0.18 10.2 3.8 2.3 2 0 0 2 2 2 0 Menin FAM183 PF14886.6 RUS84661.1 - 0.00012 22.8 1.3 0.00017 22.3 1.3 1.5 1 1 0 1 1 1 1 FAM183A and FAM183B related DUF4074 PF13293.6 RUS84661.1 - 0.34 11.2 2.6 23 5.3 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4074) Cpn60_TCP1 PF00118.24 RUS84662.1 - 2.2e-123 412.5 7.7 2e-111 373.1 1.4 2.7 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Toxin_27 PF08099.11 RUS84663.1 - 0.19 11.9 23.6 0.94 9.6 7.7 2.6 2 0 0 2 2 2 0 Scorpion calcine family UPF0506 PF11703.8 RUS84663.1 - 0.97 9.9 32.2 1.1 9.7 10.4 2.6 1 1 1 2 2 2 0 UPF0506 Toxin_12 PF07740.12 RUS84663.1 - 7.8 7.3 30.2 0.24 12.1 9.3 3.1 2 1 1 3 3 3 0 Ion channel inhibitory toxin PAP2 PF01569.21 RUS84665.1 - 2.2e-13 50.2 1.7 4.5e-13 49.1 1.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily Synaptobrevin PF00957.21 RUS84665.1 - 7.2 6.5 6.8 0.49 10.2 1.3 1.9 2 0 0 2 2 2 0 Synaptobrevin CBM_14 PF01607.24 RUS84666.1 - 3.5e-12 46.3 4.9 6.4e-12 45.4 4.9 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain LVIVD PF08309.11 RUS84666.1 - 0.87 9.0 2.5 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 LVIVD repeat Presenilin PF01080.17 RUS84666.1 - 3.1 6.5 11.2 5.9 5.5 11.2 1.4 1 0 0 1 1 1 0 Presenilin DUF4099 PF13351.6 RUS84667.1 - 0.032 14.5 1.8 0.074 13.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4099) Gly_radical PF01228.21 RUS84667.1 - 5 7.7 6.3 5.6 7.6 0.1 3.4 2 2 3 5 5 5 0 Glycine radical Fructosamin_kin PF03881.14 RUS84668.1 - 0.00046 19.5 18.3 4.7 6.3 1.8 6.8 1 1 4 5 5 5 4 Fructosamine kinase DUF2399 PF09664.10 RUS84668.1 - 0.00062 19.7 0.8 56 3.6 0.0 5.7 3 1 3 6 6 6 0 Protein of unknown function C-terminus (DUF2399) CitMHS PF03600.16 RUS84668.1 - 0.093 11.9 7.6 0.15 11.3 7.6 1.2 1 0 0 1 1 1 0 Citrate transporter Sec16 PF12932.7 RUS84668.1 - 0.28 11.8 1.6 1.1 9.9 0.2 2.6 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region WSC PF01822.19 RUS84670.1 - 4.2e-10 39.7 2.5 7.3e-05 22.9 0.4 2.4 2 0 0 2 2 2 2 WSC domain SAPS PF04499.15 RUS84670.1 - 0.3 9.8 7.1 0.34 9.6 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rad10 PF03834.14 RUS84671.1 - 0.022 14.8 0.2 0.025 14.6 0.2 1.1 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) FeThRed_B PF02943.15 RUS84671.1 - 6.3 6.9 7.2 0.91 9.6 0.3 2.3 2 1 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain Lectin_C PF00059.21 RUS84672.1 - 1.9e-61 205.5 30.1 3.3e-19 69.6 0.3 5.7 4 1 1 5 5 5 5 Lectin C-type domain ShK PF01549.24 RUS84672.1 - 2.4e-11 44.0 26.5 5.7e-07 30.0 8.0 3.7 2 0 0 2 2 2 2 ShK domain-like Chordopox_A33R PF05966.12 RUS84672.1 - 2.4e-05 23.7 1.4 0.015 14.6 0.1 2.9 3 0 0 3 3 3 2 Chordopoxvirus A33R protein UL45 PF05473.12 RUS84672.1 - 0.0092 15.6 17.8 0.69 9.5 0.0 4.4 4 1 1 5 5 5 3 UL45 protein, carbohydrate-binding C-type lectin-like DUF5316 PF17247.2 RUS84672.1 - 0.2 11.7 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) FBD PF08387.10 RUS84674.1 - 0.22 11.5 0.2 0.4 10.6 0.2 1.4 1 0 0 1 1 1 0 FBD zf-C2H2_4 PF13894.6 RUS84676.1 - 1.2e-07 32.0 21.1 0.037 14.9 0.6 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS84676.1 - 4.6e-07 29.9 20.6 0.0042 17.5 4.5 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2HE PF16278.5 RUS84676.1 - 0.0031 17.9 2.9 1.8 9.0 1.3 2.8 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 RUS84676.1 - 0.095 12.3 5.6 0.77 9.4 2.3 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS84676.1 - 0.45 11.0 3.7 54 4.4 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RUS84676.1 - 9.3 6.9 16.4 3.4 8.3 5.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Homeobox_KN PF05920.11 RUS84679.1 - 5.5e-18 64.6 1.5 8.9e-18 63.9 1.5 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS84679.1 - 7.4e-07 28.9 0.1 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Ig_3 PF13927.6 RUS84681.1 - 6.8e-28 97.1 0.0 2.4e-12 47.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS84681.1 - 5.7e-24 84.0 0.0 6.7e-10 38.9 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS84681.1 - 3.5e-18 65.7 0.0 1.2e-08 35.2 0.0 3.3 2 1 1 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS84681.1 - 2.5e-17 62.8 0.0 2e-05 24.7 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS84681.1 - 2.4e-14 53.4 0.4 0.00016 21.8 0.0 4.6 2 2 2 4 4 4 2 Immunoglobulin V-set domain fn3 PF00041.21 RUS84681.1 - 4.5e-07 30.1 0.1 0.00014 22.2 0.0 3.4 3 1 0 3 3 2 1 Fibronectin type III domain Ig_6 PF18452.1 RUS84681.1 - 3.5e-06 26.5 0.0 0.0071 15.9 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 RUS84681.1 - 1.9e-05 25.0 0.0 0.0074 16.7 0.0 3.3 4 0 0 4 4 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS84681.1 - 0.00034 20.8 0.1 0.28 11.5 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 RUS84681.1 - 0.015 15.3 0.1 6.9 6.8 0.0 3.4 3 1 0 3 3 3 0 C17orf99 Ig domain C1-set PF07654.15 RUS84681.1 - 0.02 15.3 0.0 15 6.0 0.0 3.0 2 1 0 2 2 2 0 Immunoglobulin C1-set domain C2-set PF05790.15 RUS84681.1 - 0.06 13.5 0.0 0.96 9.7 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Ank_2 PF12796.7 RUS84682.1 - 2e-15 57.2 0.0 5.5e-05 23.7 0.0 4.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS84682.1 - 4.7e-15 55.7 3.4 0.066 13.8 0.0 6.0 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS84682.1 - 2.2e-13 49.0 2.7 0.0084 16.5 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS84682.1 - 2.4e-09 37.3 0.4 0.016 15.6 0.0 5.0 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS84682.1 - 4.8e-05 23.6 2.5 0.55 10.8 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat APP_Cu_bd PF12924.7 RUS84682.1 - 0.081 13.7 0.1 0.21 12.3 0.1 1.7 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD fn3 PF00041.21 RUS84683.1 - 1.9e-09 37.7 0.1 1.9e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain Pkinase PF00069.25 RUS84684.1 - 4.3e-33 114.8 0.0 7.2e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS84684.1 - 4.7e-28 98.2 0.0 8.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 RUS84684.1 - 2.6e-05 25.2 12.5 2.6e-05 25.2 12.5 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 RUS84684.1 - 0.0043 15.9 0.0 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS84684.1 - 0.028 14.3 0.0 0.14 12.1 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Toxin_TOLIP PF00087.21 RUS84684.1 - 2.3 8.6 11.4 4.8 7.5 11.4 1.6 1 0 0 1 1 1 0 Snake toxin and toxin-like protein bZIP_2 PF07716.15 RUS84685.1 - 4.2e-09 36.3 10.3 6.3e-09 35.8 10.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS84685.1 - 3.2e-06 27.1 10.8 6.7e-06 26.1 10.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF1465 PF07323.12 RUS84685.1 - 0.0093 15.8 3.2 0.016 15.0 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) bZIP_Maf PF03131.17 RUS84685.1 - 0.21 12.1 6.8 0.37 11.3 6.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor 7tm_1 PF00001.21 RUS84687.1 - 1.1e-27 97.0 4.9 1.6e-27 96.5 4.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84687.1 - 1.6e-06 27.9 4.0 1.6e-06 27.9 4.0 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS84687.1 - 5.1e-05 23.1 8.1 0.00011 22.0 8.2 1.5 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS84687.1 - 0.013 14.9 13.5 0.0081 15.6 8.2 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4269 PF14091.6 RUS84687.1 - 0.098 12.9 0.4 0.17 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EOS1 PF12326.8 RUS84687.1 - 5.7 6.8 5.8 39 4.1 5.9 2.3 1 1 0 1 1 1 0 N-glycosylation protein DuoxA PF10204.9 RUS84688.1 - 7e-73 245.0 3.0 8.8e-73 244.7 3.0 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Med26_C PF15693.5 RUS84688.1 - 3 7.9 8.4 0.36 11.0 3.3 1.8 1 1 1 2 2 2 0 Mediator complex subunit 26 C-terminal 7TM_GPCR_Srx PF10328.9 RUS84689.1 - 5.9e-07 29.4 14.6 5.9e-07 29.4 14.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Exo_endo_phos PF03372.23 RUS84689.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4133 PF13571.6 RUS84689.1 - 5.8 7.3 5.8 2.7 8.4 0.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) 7tm_1 PF00001.21 RUS84690.1 - 2.5e-07 30.3 2.3 4.6e-07 29.4 2.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84690.1 - 0.00037 20.2 0.7 0.00061 19.5 0.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 RUS84690.1 - 0.002 17.7 1.2 0.0029 17.1 1.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srw PF10324.9 RUS84690.1 - 0.054 12.8 0.3 0.079 12.2 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Na_Pi_cotrans PF02690.15 RUS84691.1 - 2.6e-37 128.0 22.9 2.6e-23 82.7 4.9 2.9 3 0 0 3 3 3 2 Na+/Pi-cotransporter Complex1_LYR_2 PF13233.6 RUS84693.1 - 0.025 15.3 0.7 0.037 14.8 0.7 1.2 1 0 0 1 1 1 0 Complex1_LYR-like PHD PF00628.29 RUS84694.1 - 1.5e-39 133.6 112.6 1e-09 38.1 9.0 8.2 6 2 2 8 8 8 6 PHD-finger zf-HC5HC2H PF13771.6 RUS84694.1 - 1.5e-10 41.2 6.6 1.5e-10 41.2 6.6 7.5 4 2 3 7 7 7 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RUS84694.1 - 1.5e-08 34.8 6.2 1.5e-08 34.8 6.2 7.2 3 2 4 7 7 7 1 PHD-zinc-finger like domain HMG_box PF00505.19 RUS84694.1 - 4.8e-06 26.9 0.5 1.5e-05 25.3 0.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS84694.1 - 4e-05 24.1 0.9 0.00022 21.7 0.9 2.4 1 0 0 1 1 1 1 HMG-box domain Cadherin PF00028.17 RUS84695.1 - 6.3e-106 347.1 17.8 1.7e-21 76.5 1.0 7.5 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 RUS84695.1 - 1.1e-15 57.2 0.6 3.8e-06 26.6 0.0 6.8 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 RUS84695.1 - 3.6e-06 26.9 12.2 0.2 11.7 0.0 5.6 6 0 0 6 6 6 3 Cadherin-like Cadherin_pro PF08758.11 RUS84695.1 - 0.0023 18.1 0.1 0.13 12.5 0.0 3.3 3 0 0 3 3 3 1 Cadherin prodomain like DUF4834 PF16118.5 RUS84695.1 - 0.033 15.2 2.0 0.18 12.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ORF6N PF10543.9 RUS84695.1 - 0.038 14.2 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 ORF6N domain V_ATPase_I PF01496.19 RUS84695.1 - 0.18 9.7 0.1 0.29 9.0 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family He_PIG PF05345.12 RUS84695.1 - 2.7 8.3 0.0 2.7 8.3 0.0 5.2 7 0 0 7 7 7 0 Putative Ig domain Cadherin-like PF12733.7 RUS84695.1 - 5.9 7.5 8.5 4 8.0 2.8 3.7 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain 7tm_1 PF00001.21 RUS84696.1 - 4.9e-37 127.7 0.7 6.4e-37 127.3 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS84696.1 - 2.3e-08 34.1 11.2 3.2e-08 33.7 11.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS84696.1 - 4.3e-08 33.1 19.1 4.3e-08 33.1 19.1 1.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS84697.1 - 1.4e-10 41.0 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84697.1 - 0.0055 16.0 4.0 0.0069 15.7 4.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Imp-YgjV PF10688.9 RUS84697.1 - 0.013 15.3 1.9 0.017 15.0 1.9 1.1 1 0 0 1 1 1 0 Bacterial inner membrane protein TetR_C_13 PF16925.5 RUS84697.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 RUS84700.1 - 4e-23 82.1 0.0 6.3e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS84700.1 - 1.8e-13 50.4 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RUS84700.1 - 0.081 12.5 0.1 9.9 5.7 0.2 2.3 2 0 0 2 2 2 0 RIO1 family MBR1 PF17058.5 RUS84700.1 - 0.62 10.3 8.6 1.4 9.2 8.6 1.5 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 Guanylate_cyc PF00211.20 RUS84701.1 - 9.3e-58 194.9 0.3 6.1e-49 166.1 0.1 2.3 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS84701.1 - 4.5e-12 45.8 0.1 9.8e-11 41.4 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS84701.1 - 1.6e-10 40.8 0.0 1.3e-09 37.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain TelA PF05816.11 RUS84701.1 - 0.0003 20.0 0.1 0.00044 19.4 0.1 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) HNOBA PF07701.14 RUS84701.1 - 0.004 16.6 0.7 0.0071 15.8 0.7 1.3 1 0 0 1 1 1 1 Heme NO binding associated YtxC PF08812.11 RUS84701.1 - 0.11 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 YtxC-like family TMEM214 PF10151.9 RUS84704.1 - 3.2e-157 524.9 18.7 4.1e-157 524.5 18.7 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator TatD_DNase PF01026.21 RUS84705.1 - 7e-55 186.2 0.0 8e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase LBP_C PF17386.2 RUS84706.1 - 0.33 10.9 1.1 0.54 10.2 0.4 1.7 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain Patched PF02460.18 RUS84707.1 - 2.4e-61 207.9 23.8 6.1e-38 130.5 11.7 2.6 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RUS84707.1 - 5.4e-25 88.0 3.6 5.4e-25 88.0 3.6 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Hexapep PF00132.24 RUS84709.1 - 3.6e-47 156.4 83.3 3.8e-05 23.2 3.1 11.1 1 1 7 9 9 9 9 Bacterial transferase hexapeptide (six repeats) CsrA PF02599.16 RUS84709.1 - 1.2e-08 34.7 35.1 26 4.9 0.2 13.8 1 1 4 5 5 5 0 Global regulator protein family Phage_SSB PF16773.5 RUS84709.1 - 3.4e-05 23.9 64.2 1.8e+04 -49.3 64.2 10.7 1 1 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein Biotin_lipoyl PF00364.22 RUS84709.1 - 0.0017 18.1 118.6 36 4.3 3.3 19.1 1 1 1 2 2 2 0 Biotin-requiring enzyme MspA PF09203.11 RUS84709.1 - 0.021 14.7 47.8 1.8e+04 -29.4 47.8 5.6 1 1 0 1 1 1 0 MspA Phage_head_fibr PF11133.8 RUS84709.1 - 0.6 9.5 49.9 1.8e+04 -33.4 49.8 6.5 1 1 0 1 1 1 0 Head fiber protein DUF3127 PF11325.8 RUS84709.1 - 0.67 10.2 51.0 68 3.8 0.5 12.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3127) Pkinase_Tyr PF07714.17 RUS84710.1 - 3.9e-94 314.8 0.0 4.7e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS84710.1 - 6.3e-49 166.7 0.0 8.4e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS84710.1 - 1.3e-23 82.8 0.0 4e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 SH2 domain Haspin_kinase PF12330.8 RUS84710.1 - 2.1e-05 23.7 0.1 3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RUS84710.1 - 0.0021 17.4 0.2 0.0037 16.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS84710.1 - 0.064 13.2 0.1 0.42 10.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.17 RUS84712.1 - 1.6e-70 238.0 14.3 5.7e-70 236.2 12.7 2.4 1 1 1 2 2 2 1 Cytochrome c/c1 heme lyase RRM_5 PF13893.6 RUS84713.1 - 2.6e-50 169.2 7.0 1.2e-32 112.2 0.1 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RUS84713.1 - 6.5e-30 102.8 6.5 3.6e-09 36.3 0.1 5.2 5 1 1 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RUS84713.1 - 6.7e-15 55.1 0.0 2.7e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 RUS84713.1 - 1.8e-06 27.7 0.1 4.7 7.1 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif RL PF17797.1 RUS84713.1 - 0.0054 16.7 0.1 3 7.9 0.0 2.9 3 0 0 3 3 3 2 RL domain Calcipressin PF04847.12 RUS84713.1 - 0.077 12.7 0.1 0.65 9.7 0.1 2.3 2 0 0 2 2 2 0 Calcipressin RRM_5 PF13893.6 RUS84714.1 - 6.5e-39 132.4 4.9 5.2e-30 103.6 0.1 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 RUS84714.1 - 1.2e-24 85.9 0.2 1.3e-06 28.1 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 RUS84714.1 - 5.8e-14 52.1 0.0 6.3e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 RUS84714.1 - 2.3e-05 24.2 0.1 0.2 11.5 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Pentapeptide_4 PF13599.6 RUS84716.1 - 1.8e-20 72.8 52.2 3.3e-05 24.0 8.3 4.7 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) DUF3843 PF12954.7 RUS84717.1 - 0.0024 16.9 2.7 0.0024 16.9 2.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3843) Spt20 PF12090.8 RUS84717.1 - 2.6 7.6 123.5 0.13 11.8 10.8 5.6 5 0 0 5 5 5 0 Spt20 family Branch PF02485.21 RUS84719.1 - 2.5e-26 92.7 0.0 2.9e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme PLAC8 PF04749.17 RUS84720.1 - 2.6e-14 54.0 9.6 3.6e-14 53.6 9.6 1.2 1 0 0 1 1 1 1 PLAC8 family OATP PF03137.20 RUS84721.1 - 3e-43 148.0 10.4 1.9e-42 145.3 10.4 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS84721.1 - 3.2e-08 32.9 14.8 5e-08 32.3 14.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS84721.1 - 0.0014 18.7 3.8 0.0033 17.5 3.8 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS84721.1 - 0.067 13.2 3.1 0.14 12.2 3.1 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain OATP PF03137.20 RUS84722.1 - 9.1e-10 37.4 1.5 1.1e-09 37.2 1.5 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 RUS84722.1 - 0.1 12.7 4.9 0.16 12.1 4.9 1.3 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF3021 PF11457.8 RUS84722.1 - 0.22 11.8 3.9 0.36 11.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF805 PF05656.14 RUS84722.1 - 0.8 10.1 5.6 1.5 9.3 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2070 PF09843.9 RUS84722.1 - 2 6.6 6.2 2.3 6.4 6.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) F-box PF00646.33 RUS84723.1 - 1.7e-05 24.6 0.7 4.3e-05 23.3 0.7 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS84723.1 - 0.00052 19.9 0.2 0.0014 18.4 0.2 1.8 1 1 0 1 1 1 1 F-box-like YcgL PF05166.13 RUS84724.1 - 0.15 12.5 0.1 0.75 10.2 0.0 2.0 2 0 0 2 2 2 0 YcgL domain 7tm_1 PF00001.21 RUS84725.1 - 3.9e-13 49.3 11.4 4.9e-13 49.0 11.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS84725.1 - 0.00012 21.5 14.0 0.019 14.3 8.6 2.9 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF418 PF04235.12 RUS84725.1 - 0.042 13.8 3.0 4.2 7.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) Phage_holin_3_6 PF07332.11 RUS84725.1 - 2.1 8.4 6.1 5.9 7.0 0.1 3.2 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Sacchrp_dh_C PF16653.5 RUS84726.1 - 1.7e-83 280.8 0.0 3.5e-83 279.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 RUS84726.1 - 3.5e-26 92.1 0.2 1.2e-25 90.4 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 RUS84726.1 - 5.2e-22 78.5 0.0 1.2e-21 77.3 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 RUS84726.1 - 3.2e-09 36.4 0.0 5.1e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RUS84726.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 7tm_1 PF00001.21 RUS84727.1 - 7.5e-20 71.4 5.0 9.6e-20 71.0 5.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) p450 PF00067.22 RUS84727.1 - 4e-11 42.3 0.0 4.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 7TM_GPCR_Srx PF10328.9 RUS84727.1 - 0.031 13.9 3.5 0.044 13.4 3.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS84727.1 - 0.082 12.6 3.3 0.32 10.7 3.3 1.8 1 1 0 1 1 1 0 Olfactory receptor 7tm_1 PF00001.21 RUS84728.1 - 4.1e-42 144.3 4.6 5.6e-42 143.9 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84728.1 - 1.3e-09 37.8 0.7 2.7e-09 36.8 0.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS84728.1 - 9.2e-09 35.3 2.6 9.2e-09 35.3 2.6 1.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS84728.1 - 3e-08 33.7 4.3 4.9e-08 33.0 4.3 1.3 1 0 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 RUS84728.1 - 4.8e-05 23.2 9.1 8e-05 22.5 7.2 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DUF3953 PF13129.6 RUS84728.1 - 0.019 14.7 0.6 0.019 14.7 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF971 PF06155.12 RUS84728.1 - 0.081 13.6 0.1 0.2 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) 7TM_GPCR_Srw PF10324.9 RUS84728.1 - 0.089 12.1 0.2 0.089 12.1 0.2 2.0 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw Ac76 PF05814.11 RUS84728.1 - 0.34 11.0 2.3 3.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Orf76 (Ac76) DUF2207 PF09972.9 RUS84728.1 - 0.36 9.5 2.8 0.76 8.5 1.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Aminotran_1_2 PF00155.21 RUS84729.1 - 3.1e-34 118.7 0.0 3.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RUS84729.1 - 0.00021 20.7 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 RUS84729.1 - 0.027 13.3 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Crust_neurohorm PF01147.17 RUS84730.1 - 0.039 13.8 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family zf-H2C2_2 PF13465.6 RUS84731.1 - 3.2e-64 210.7 104.6 4.8e-09 36.2 0.9 13.1 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.26 RUS84731.1 - 4e-48 159.2 120.8 1.9e-05 24.9 0.7 13.2 13 0 0 13 13 13 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS84731.1 - 2.6e-41 136.7 112.8 0.001 19.7 2.2 13.1 13 0 0 13 13 13 13 C2H2-type zinc finger zf-met PF12874.7 RUS84731.1 - 1.1e-18 67.0 86.8 0.0099 16.2 3.0 13.6 12 1 2 14 14 14 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS84731.1 - 2.6e-17 62.4 110.7 0.00023 21.1 0.3 14.6 15 0 0 15 15 15 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS84731.1 - 4.3e-13 49.2 89.1 0.017 15.4 1.7 13.2 14 0 0 14 14 13 10 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS84731.1 - 9.9e-07 28.4 3.4 7.7e-06 25.6 0.8 11.4 12 0 0 12 12 12 2 zinc-finger C2H2-type C1_1 PF00130.22 RUS84731.1 - 6.2e-05 22.8 68.2 0.0047 16.8 0.7 9.3 4 3 5 9 9 9 5 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 RUS84731.1 - 0.029 14.4 52.1 5.5 7.1 5.2 7.4 1 1 3 4 4 3 0 Double zinc ribbon DUF3268 PF11672.8 RUS84731.1 - 0.038 14.3 39.4 0.27 11.6 0.7 6.1 4 1 4 8 8 8 0 zinc-finger-containing domain zf-C2HE PF16278.5 RUS84731.1 - 0.04 14.4 1.0 0.04 14.4 1.0 11.6 4 3 8 12 12 11 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 RUS84731.1 - 0.063 13.4 66.8 1.5 9.0 2.0 10.2 5 3 6 11 11 11 0 Zinc ribbon domain ADK_lid PF05191.14 RUS84731.1 - 0.063 13.3 43.6 0.4 10.7 1.5 8.1 6 5 3 9 9 9 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 RUS84731.1 - 0.29 11.9 53.3 0.33 11.7 1.4 6.6 1 1 4 6 6 6 0 zinc-ribbon family zf-C2HC_2 PF13913.6 RUS84731.1 - 0.38 10.7 0.2 0.38 10.7 0.2 12.9 13 0 0 13 13 13 0 zinc-finger of a C2HC-type BolA PF01722.18 RUS84731.1 - 1.1 9.6 18.7 15 6.0 0.0 5.7 4 1 2 6 6 6 0 BolA-like protein RCC1 PF00415.18 RUS84732.1 - 3.7e-36 123.5 8.7 1.6e-12 47.8 0.1 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS84732.1 - 6.7e-15 54.4 23.8 4.2e-08 32.8 2.5 5.3 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Gam PF06064.11 RUS84732.1 - 0.04 14.1 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam PH_13 PF16652.5 RUS84733.1 - 0.045 13.6 0.1 10 5.9 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain ApeC PF16977.5 RUS84734.1 - 4.9e-32 111.6 0.0 7.3e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of apextrin TraF_2 PF13729.6 RUS84734.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Thyroglobulin_1 PF00086.18 RUS84735.1 - 0.0092 15.6 0.6 0.35 10.6 0.2 2.4 1 1 0 1 1 1 1 Thyroglobulin type-1 repeat ABC1 PF03109.16 RUS84736.1 - 3.7e-36 123.9 0.0 6.7e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family HMG_box_2 PF09011.10 RUS84736.1 - 0.16 12.6 0.1 0.39 11.3 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain Forkhead PF00250.18 RUS84737.1 - 1.2e-26 92.8 0.1 2.3e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain Ras PF00071.22 RUS84738.1 - 1.9e-23 82.9 0.0 2.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS84738.1 - 4e-05 23.8 0.0 0.0002 21.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS84738.1 - 6.2e-05 23.0 0.2 0.011 15.6 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RUS84738.1 - 0.0035 16.9 0.2 0.012 15.1 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 RUS84738.1 - 0.026 15.0 0.0 0.045 14.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS84738.1 - 0.027 14.7 0.3 0.39 11.0 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 RUS84738.1 - 0.036 14.5 0.1 0.052 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 RUS84738.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Actin PF00022.19 RUS84740.1 - 7.1e-42 143.4 0.0 7.8e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Actin PHD PF00628.29 RUS84741.1 - 0.00013 21.7 5.2 0.00038 20.3 5.2 1.9 1 0 0 1 1 1 1 PHD-finger DUF4604 PF15377.6 RUS84741.1 - 1.3 9.4 46.3 3.1 8.2 46.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Endostatin PF06482.11 RUS84741.1 - 3.4 7.1 12.9 1.8 8.0 5.6 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF3807 PF12720.7 RUS84741.1 - 5.1 7.3 36.2 5.1 7.3 13.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DDE_1 PF03184.19 RUS84742.1 - 2.8e-16 59.7 2.3 4.4e-16 59.0 0.4 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.16 RUS84742.1 - 7.1e-08 32.1 0.2 1.2e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 RUS84742.1 - 3.9e-06 26.7 0.1 8.5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RUS84742.1 - 0.00013 21.9 0.1 0.00027 20.9 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SAP PF02037.27 RUS84743.1 - 4.4e-10 39.1 1.9 6.8e-10 38.5 1.0 1.8 2 0 0 2 2 2 1 SAP domain PH PF00169.29 RUS84744.1 - 1.6e-12 47.9 0.4 1.1e-11 45.1 0.1 2.5 2 0 0 2 2 2 1 PH domain DUF2312 PF10073.9 RUS84744.1 - 0.012 15.2 6.7 0.012 15.2 6.7 3.9 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1664 PF07889.12 RUS84744.1 - 0.13 12.3 33.0 0.031 14.3 10.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) PH_11 PF15413.6 RUS84744.1 - 0.75 10.3 8.1 0.15 12.5 0.5 3.6 2 2 0 2 2 2 0 Pleckstrin homology domain CENP-F_leu_zip PF10473.9 RUS84744.1 - 3.2 7.8 61.6 0.86 9.6 36.5 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HEAT_2 PF13646.6 RUS84745.1 - 1.1e-35 121.9 9.8 4.6e-14 52.6 0.3 3.7 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 RUS84745.1 - 3.5e-28 95.4 8.1 0.00076 19.9 0.0 7.2 7 0 0 7 7 7 6 PBS lyase HEAT-like repeat HEAT PF02985.22 RUS84745.1 - 3.7e-07 29.8 9.9 0.11 12.8 0.2 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 RUS84745.1 - 2e-05 25.0 4.7 1.2 9.8 0.5 5.0 3 2 2 5 5 5 2 HEAT-like repeat Arm PF00514.23 RUS84745.1 - 0.0034 17.4 4.1 0.4 10.8 0.0 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 RUS84745.1 - 0.017 15.5 0.1 2 8.8 0.0 3.0 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Vitellogenin_N PF01347.22 RUS84745.1 - 0.14 10.5 0.1 6.4 5.0 0.0 2.8 3 0 0 3 3 3 0 Lipoprotein amino terminal region DUF19 PF01579.18 RUS84747.1 - 0.0094 15.8 0.4 0.048 13.5 0.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF19) Radial_spoke PF04712.12 RUS84749.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Fer4_2 PF12797.7 RUS84749.1 - 0.15 12.2 4.0 1.1 9.5 0.3 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 RUS84749.1 - 0.5 11.0 6.9 8.9 7.1 1.5 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain 7TM_GPCR_Srx PF10328.9 RUS84751.1 - 1e-06 28.6 20.2 4.4e-06 26.5 20.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS84751.1 - 0.00052 19.4 11.8 0.001 18.4 11.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS84751.1 - 0.38 10.7 11.4 0.18 11.8 7.0 2.4 2 1 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa CBM_14 PF01607.24 RUS84752.1 - 1.6e-15 57.0 9.7 1.6e-13 50.6 5.9 2.2 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Arylesterase PF01731.20 RUS84753.1 - 1e-13 51.3 0.0 2.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 RUS84753.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 RUS84753.1 - 0.00026 21.1 0.0 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 Strictosidine synthase Lactonase PF10282.9 RUS84753.1 - 0.00079 18.8 0.0 0.0041 16.4 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller 7TM_GPCR_Srw PF10324.9 RUS84754.1 - 3.2e-11 43.1 22.4 7.1e-11 41.9 22.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS84754.1 - 1.2e-08 34.9 20.8 2.4e-08 34.0 19.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS84754.1 - 4.4e-06 26.2 21.9 4.4e-06 26.2 21.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS84754.1 - 1.1 9.3 16.8 0.035 14.1 9.3 2.2 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF1189 PF06691.11 RUS84754.1 - 6.3 6.3 10.7 0.21 11.1 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1189) Aminotran_1_2 PF00155.21 RUS84755.1 - 1.7e-38 132.8 0.0 2e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Kinesin PF00225.23 RUS84756.1 - 5.9e-95 318.0 0.7 1e-94 317.2 0.7 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS84756.1 - 2.4e-15 56.8 1.8 1.1e-14 54.6 0.1 2.6 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 RUS84756.1 - 0.0064 16.6 6.2 0.0064 16.6 6.2 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Type2_restr_D3 PF16902.5 RUS84756.1 - 0.08 12.9 0.2 0.48 10.4 0.1 2.4 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Fib_alpha PF08702.10 RUS84756.1 - 0.54 10.4 10.6 12 6.0 5.8 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pacifastin_I PF05375.13 RUS84757.1 - 2.5e-15 55.9 78.4 2.1e-07 30.5 7.2 7.3 6 1 1 7 7 7 6 Pacifastin inhibitor (LCMII) VWC PF00093.18 RUS84757.1 - 0.00029 21.1 63.0 0.03 14.7 3.9 6.1 5 1 1 6 6 6 4 von Willebrand factor type C domain PCMT PF01135.19 RUS84758.1 - 7.9e-23 81.3 0.0 1.3e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 RUS84758.1 - 4.8e-05 23.6 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 2 SOCS box Methyltransf_25 PF13649.6 RUS84758.1 - 0.0021 18.7 0.0 0.0056 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 RUS84758.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 GCD14 PF08704.10 RUS84758.1 - 0.011 15.4 2.8 0.017 14.8 0.0 2.5 3 0 0 3 3 3 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 RUS84758.1 - 0.017 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1190 PF06693.11 RUS84758.1 - 0.028 14.8 0.2 0.028 14.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1190) MBT PF02820.18 RUS84759.1 - 4.5e-86 283.2 1.8 7.4e-28 96.7 0.0 4.1 4 0 0 4 4 4 3 mbt repeat zf-C2HC PF01530.18 RUS84759.1 - 1e-25 89.6 25.7 8.7e-14 51.4 8.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.30 RUS84759.1 - 1.2e-08 35.3 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS84759.1 - 0.0018 18.4 0.1 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RUS84759.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Peptidase_C1 PF00112.23 RUS84760.1 - 1.5e-50 172.3 2.7 2e-50 171.9 2.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Pacifastin_I PF05375.13 RUS84760.1 - 0.003 17.2 1.6 0.0088 15.8 1.6 1.8 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Peptidase_C1_2 PF03051.15 RUS84760.1 - 0.031 13.1 0.7 0.083 11.7 0.4 1.7 2 0 0 2 2 2 0 Peptidase C1-like family gag_pre-integrs PF13976.6 RUS84760.1 - 0.038 13.9 0.2 0.077 12.9 0.2 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain CRC_subunit PF08624.10 RUS84761.1 - 0.054 13.9 0.0 0.097 13.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin remodelling complex Rsc7/Swp82 subunit bZIP_2 PF07716.15 RUS84762.1 - 2.6e-10 40.2 9.8 2.6e-10 40.2 9.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper PPP4R2 PF09184.11 RUS84762.1 - 0.00042 20.0 11.4 0.00064 19.4 11.4 1.3 1 0 0 1 1 1 1 PPP4R2 Roughex PF06020.11 RUS84762.1 - 0.0046 16.1 7.5 0.0073 15.5 7.5 1.3 1 0 0 1 1 1 1 Drosophila roughex protein GPI2 PF06432.11 RUS84762.1 - 0.0069 15.9 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3671 PF12420.8 RUS84762.1 - 0.0072 16.4 6.6 0.0072 16.4 6.6 2.5 1 1 1 2 2 1 1 Protein of unknown function TraG_N PF07916.11 RUS84762.1 - 0.016 14.1 0.9 0.025 13.4 0.9 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region bZIP_1 PF00170.21 RUS84762.1 - 0.14 12.3 7.5 0.3 11.2 7.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor RRN3 PF05327.11 RUS84762.1 - 0.18 10.3 21.7 0.35 9.4 21.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EI24 PF07264.11 RUS84762.1 - 0.65 10.2 5.3 5.8 7.1 6.1 1.9 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Connexin PF00029.19 RUS84762.1 - 0.74 9.5 3.7 4.5 7.0 0.0 2.8 3 1 1 4 4 4 0 Connexin DUF2207 PF09972.9 RUS84762.1 - 1.3 7.7 15.9 4.1 6.1 15.9 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TRAP_alpha PF03896.16 RUS84762.1 - 3.7 6.7 16.9 0.69 9.1 12.9 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TMEM154 PF15102.6 RUS84763.1 - 0.0025 17.7 5.9 0.0088 16.0 5.9 2.0 1 1 0 1 1 1 1 TMEM154 protein family TerB PF05099.13 RUS84763.1 - 0.0082 16.1 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF2408 PF10303.9 RUS84763.1 - 0.015 15.9 2.0 0.019 15.5 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) RIFIN PF02009.16 RUS84763.1 - 0.022 14.7 3.3 0.032 14.1 3.3 1.3 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 RUS84763.1 - 0.11 13.4 0.8 0.65 10.9 0.0 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cation_ATPase_C PF00689.21 RUS84763.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Glycophorin_A PF01102.18 RUS84763.1 - 2.9 8.1 6.9 0.63 10.3 2.0 2.5 2 2 0 2 2 2 0 Glycophorin A Pex14_N PF04695.13 RUS84763.1 - 7 7.3 12.4 0.048 14.3 2.2 2.3 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ARID PF01388.21 RUS84764.1 - 1.1e-23 83.6 0.1 8.2e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RBB1NT PF08169.11 RUS84764.1 - 2e-22 79.1 0.0 9.2e-22 77.0 0.0 2.3 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Tudor-knot PF11717.8 RUS84764.1 - 3.1e-09 36.6 1.0 1.3e-08 34.6 1.0 2.2 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF365 PF04033.12 RUS84764.1 - 0.022 15.0 0.2 0.37 11.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF365) Tudor_2 PF18104.1 RUS84764.1 - 0.089 12.5 1.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 RUS84764.1 - 0.16 11.9 0.9 4.2 7.3 0.0 2.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain 7tm_1 PF00001.21 RUS84765.1 - 1.3e-50 172.2 11.0 1.7e-50 171.8 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS84765.1 - 3.4e-05 23.6 7.4 5.1e-05 23.0 7.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS84765.1 - 0.00028 20.3 6.3 0.00045 19.7 6.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0715 PF17094.5 RUS84765.1 - 0.0058 17.2 1.3 0.0058 17.2 1.3 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0715) 7tm_4 PF13853.6 RUS84765.1 - 0.0084 15.9 2.2 0.0084 15.9 2.2 1.6 1 1 0 1 1 1 1 Olfactory receptor DUF3671 PF12420.8 RUS84765.1 - 4.8 7.3 5.4 0.54 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DEAD PF00270.29 RUS84767.1 - 4e-05 23.4 0.0 0.0061 16.3 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 RUS84767.1 - 0.0074 16.3 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain ResIII PF04851.15 RUS84767.1 - 0.046 13.7 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M13 PF01431.21 RUS84768.1 - 1.4e-42 145.6 1.0 2.5e-42 144.8 0.2 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 RUS84768.1 - 2.3e-28 100.0 0.2 3.5e-28 99.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M13 Nop14 PF04147.12 RUS84768.1 - 0.0021 16.4 19.3 0.0029 15.9 19.3 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS84768.1 - 0.0045 16.5 19.2 0.0064 16.0 19.2 1.2 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 RUS84768.1 - 0.059 12.8 17.9 0.1 12.0 17.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 RUS84768.1 - 0.15 10.5 17.0 0.21 10.0 17.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 RUS84768.1 - 0.29 10.3 0.7 0.44 9.7 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 RUS84768.1 - 0.3 9.8 3.7 0.37 9.5 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 RUS84768.1 - 0.31 9.1 38.6 0.47 8.5 38.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 RUS84768.1 - 0.59 10.1 27.8 0.76 9.7 27.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 RUS84768.1 - 1.1 9.7 11.5 0.4 11.1 5.8 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SpoIIIAH PF12685.7 RUS84768.1 - 1.4 8.7 6.9 1.1 9.1 2.9 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein CNDH2_C PF16858.5 RUS84768.1 - 2.5 7.9 10.0 4.6 7.0 10.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 RUS84768.1 - 2.7 7.2 20.6 4 6.7 20.6 1.2 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 RUS84768.1 - 6.9 5.3 5.5 10 4.8 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M13_N PF05649.13 RUS84769.1 - 2.3e-39 136.2 0.0 1.9e-38 133.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M13 Sugar_tr PF00083.24 RUS84771.1 - 1.3e-28 100.1 12.2 1.8e-28 99.6 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS84771.1 - 2.7e-14 52.9 34.4 3.4e-07 29.5 20.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.6 RUS84771.1 - 1.7 8.6 7.4 54 3.7 0.4 3.6 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF5345 PF17280.2 RUS84771.1 - 1.8 8.6 4.7 2.8 8.0 0.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Glycos_transf_2 PF00535.26 RUS84772.1 - 2.3e-31 108.9 0.0 3.7e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS84772.1 - 4.3e-10 39.9 0.0 6.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS84772.1 - 9.8e-05 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS84772.1 - 0.00057 19.4 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PA28_beta PF02252.18 RUS84773.1 - 5.1e-57 191.6 3.4 5.1e-57 191.6 3.4 2.1 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 RUS84773.1 - 1.7e-11 44.0 2.0 3.8e-11 42.9 0.9 2.1 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit I_LWEQ PF01608.17 RUS84773.1 - 0.51 10.6 3.5 6.7 6.9 0.0 2.9 3 1 0 3 3 3 0 I/LWEQ domain Com_YlbF PF06133.11 RUS84773.1 - 6.7 7.4 10.3 6.7 7.4 2.5 3.1 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Myosin_head PF00063.21 RUS84774.1 - 1.6e-141 472.8 0.1 1.8e-141 472.7 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.12 RUS84774.1 - 0.0099 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 RUS84774.1 - 0.02 15.4 0.1 0.1 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RUS84774.1 - 0.072 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RUS84774.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 RUS84775.1 - 4.8e-28 98.1 0.0 8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS84775.1 - 2.2e-13 50.6 0.0 3.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RUS84775.1 - 1.5e-06 28.3 0.0 3.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS84775.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 RUS84775.1 - 0.0051 17.5 0.2 0.041 14.6 0.0 2.5 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 RUS84775.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 GlcNAc PF11397.8 RUS84775.1 - 0.15 11.5 0.5 0.36 10.2 0.5 1.4 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) Vps16_C PF04840.12 RUS84776.1 - 1e-08 34.6 0.7 0.0001 21.5 0.1 2.5 2 1 0 2 2 2 2 Vps16, C-terminal region BLOC1_2 PF10046.9 RUS84776.1 - 0.086 13.1 1.1 6.3 7.2 0.3 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glycos_transf_2 PF00535.26 RUS84777.1 - 2.4e-31 108.9 0.0 4.6e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS84777.1 - 1.9e-15 57.2 2.0 2.9e-15 56.6 2.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 RUS84777.1 - 6.9e-08 32.3 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS84777.1 - 8.3e-06 25.4 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 RUS84777.1 - 1.9e-05 24.7 0.0 0.00022 21.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CDtoxinA PF03498.14 RUS84777.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain MFS_1 PF07690.16 RUS84778.1 - 1.6e-13 50.3 23.5 1.6e-13 50.3 23.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily TetR_C_12 PF16914.5 RUS84778.1 - 0.0029 17.7 0.4 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial transcriptional repressor C-terminal DUF2516 PF10724.9 RUS84778.1 - 3.5 8.0 19.3 1.4 9.3 6.8 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2516) zf-C2H2_4 PF13894.6 RUS84779.1 - 1.2e-07 31.9 196.3 0.29 12.1 3.0 26.0 26 0 0 26 26 26 15 C2H2-type zinc finger zf-met PF12874.7 RUS84779.1 - 1.8e-06 28.2 108.8 0.056 13.9 1.1 21.1 21 0 0 21 21 21 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS84779.1 - 0.0013 19.0 131.2 0.012 15.9 2.6 20.8 22 0 0 22 22 22 10 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS84779.1 - 0.0056 16.7 0.6 0.0056 16.7 0.6 16.4 21 0 0 21 21 21 4 C2H2-type zinc finger DUF4187 PF13821.6 RUS84779.1 - 0.03 14.1 7.8 1.2 8.9 0.0 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 RUS84779.1 - 0.17 12.4 0.1 0.073 13.6 1.2 23.9 26 0 0 26 26 26 0 Zinc finger, C2H2 type 7tm_1 PF00001.21 RUS84780.1 - 1.3e-08 34.5 25.0 1.3e-08 34.5 25.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CrgA PF06781.12 RUS84780.1 - 0.27 11.3 2.3 0.43 10.7 0.2 2.4 1 1 1 2 2 2 0 Cell division protein CrgA Neur_chan_memb PF02932.16 RUS84781.1 - 3.3e-32 112.5 5.5 4.3e-27 95.7 2.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS84781.1 - 4.5e-25 88.4 3.1 1.1e-23 83.8 3.1 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain MNHE PF01899.16 RUS84781.1 - 0.27 11.0 3.2 0.44 10.3 3.2 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit CCDC32 PF14989.6 RUS84782.1 - 1e-16 61.3 0.4 1.9e-16 60.4 0.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing 32 Pex14_N PF04695.13 RUS84782.1 - 0.068 13.8 1.3 0.12 13.0 1.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sod_Cu PF00080.20 RUS84783.1 - 1.4e-12 48.0 0.1 2.2e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 RUS84783.1 - 9.9e-09 35.5 0.4 3.5e-08 33.8 0.2 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain IBR PF01485.21 RUS84785.1 - 2.6e-06 27.5 6.5 2.6e-06 27.5 6.5 3.2 1 1 2 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 RUS84785.1 - 0.0016 18.4 1.5 0.0016 18.4 1.5 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS84785.1 - 0.0042 17.4 4.0 0.0042 17.4 4.0 3.5 3 2 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 RUS84785.1 - 0.38 10.7 15.5 0.13 12.2 4.7 3.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Mob_synth_C PF06463.13 RUS84785.1 - 0.4 10.6 4.0 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 RUS84785.1 - 0.53 10.1 13.8 1.6 8.6 0.7 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 RUS84785.1 - 1.6 8.6 22.1 0.095 12.6 4.7 3.3 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Guanylate_kin PF00625.21 RUS84786.1 - 8.3e-46 156.0 0.0 2.2e-44 151.3 0.0 2.5 1 1 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 RUS84786.1 - 2.9e-15 56.4 3.5 9.5e-13 48.3 1.9 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS84786.1 - 2.9e-12 46.2 0.0 1.6e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS84786.1 - 1.4e-10 41.3 0.3 6.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 PDZ domain L27_N PF09060.10 RUS84786.1 - 3.2e-07 30.3 0.6 6.8e-07 29.2 0.6 1.6 1 0 0 1 1 1 1 L27_N L27 PF02828.16 RUS84786.1 - 8.6e-06 25.4 4.3 6.5e-05 22.6 0.6 2.9 2 0 0 2 2 2 1 L27 domain SH3_2 PF07653.17 RUS84786.1 - 0.00018 21.2 0.0 0.00037 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PolyA_pol PF01743.20 RUS84787.1 - 2e-33 115.5 1.0 3.7e-33 114.6 1.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 RUS84787.1 - 4.9e-10 39.0 0.0 1.8e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A ResIII PF04851.15 RUS84788.1 - 1.4e-21 77.3 0.1 1.6e-20 73.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS84788.1 - 1.4e-20 73.7 0.1 6.7e-20 71.5 0.1 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS84788.1 - 1.2e-17 64.2 0.0 7.3e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase FANCM-MHF_bd PF16783.5 RUS84788.1 - 3.8e-11 43.1 0.5 1.5e-10 41.2 0.5 2.1 1 0 0 1 1 1 1 FANCM to MHF binding domain Spt5_N PF11942.8 RUS84789.1 - 4.7 8.3 16.4 0.15 13.0 1.0 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal ERCC4 PF02732.15 RUS84790.1 - 7e-08 32.8 0.5 1.5e-07 31.7 0.5 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.7 RUS84790.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-C4 PF00105.18 RUS84791.1 - 7.7e-32 109.6 24.4 2.5e-25 88.7 12.7 2.8 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS84791.1 - 9.2e-07 28.6 0.0 7.2e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor FoP_duplication PF13865.6 RUS84791.1 - 8.4 7.0 9.3 0.17 12.4 0.8 2.7 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 ETX_MTX2 PF03318.13 RUS84792.1 - 8.5e-05 22.4 1.3 0.00011 22.1 1.3 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 RUS84792.1 - 0.015 14.5 0.3 1.9 7.6 0.1 2.1 1 1 1 2 2 2 0 Aerolysin toxin CUB_2 PF02408.20 RUS84792.1 - 0.11 12.2 0.8 2.9 7.7 0.1 2.5 2 1 0 2 2 2 0 CUB-like domain PT PF04886.12 RUS84797.1 - 3.6e-86 282.4 295.8 1.8e+04 -204.1 295.8 10.1 1 1 0 1 1 1 0 PT repeat DUF1647 PF07801.11 RUS84798.1 - 2.3e-05 24.2 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Sulfate_transp PF00916.20 RUS84799.1 - 3.9e-98 328.7 15.5 5.2e-98 328.3 15.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RUS84799.1 - 1.3e-13 50.6 0.0 2.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain Tim17 PF02466.19 RUS84799.1 - 0.24 11.8 2.0 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family IncFII_repA PF02387.15 RUS84801.1 - 0.11 11.7 0.5 0.18 11.0 0.5 1.2 1 0 0 1 1 1 0 IncFII RepA protein family SecIII_SopE_N PF05364.14 RUS84801.1 - 0.54 10.4 3.0 0.97 9.6 3.0 1.3 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Med13_C PF06333.12 RUS84802.1 - 7.6e-100 334.4 0.3 7.6e-100 334.4 0.3 3.0 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 RUS84802.1 - 5.9e-62 209.7 0.0 5.9e-62 209.7 0.0 2.9 3 1 0 3 3 3 1 MID domain of medPIWI Med13_N PF11597.8 RUS84802.1 - 4.4e-18 65.7 0.0 1.9e-17 63.6 0.0 2.1 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal SUIM_assoc PF16619.5 RUS84802.1 - 0.9 9.6 15.4 2.9 8.0 0.6 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4774 PF15999.5 RUS84803.1 - 0.047 13.5 1.0 58 3.6 0.0 4.5 3 1 3 6 6 6 0 Domain of unknown function (DUF4774) PALP PF00291.25 RUS84806.1 - 1.5e-67 228.1 1.5 1.8e-67 227.9 1.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2408 PF10303.9 RUS84807.1 - 0.64 10.6 3.7 0.23 12.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GPCR_chapero_1 PF11904.8 RUS84808.1 - 1.3e-100 336.8 0.3 2e-100 336.2 0.0 1.5 2 0 0 2 2 2 1 GPCR-chaperone Ank_2 PF12796.7 RUS84808.1 - 1.3e-10 41.7 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS84808.1 - 5.1e-08 33.0 0.1 3.8e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS84808.1 - 7.8e-08 32.0 0.0 0.0044 17.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS84808.1 - 3e-07 30.6 0.0 0.00012 22.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS84808.1 - 7.2e-06 26.5 0.0 2.2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) UIM PF02809.20 RUS84808.1 - 0.0028 17.4 0.1 0.0028 17.4 0.1 5.8 6 0 0 6 6 6 3 Ubiquitin interaction motif DUF3774 PF12609.8 RUS84808.1 - 0.11 13.5 0.1 0.36 11.9 0.1 1.9 1 0 0 1 1 1 0 Wound-induced protein Helicase_C PF00271.31 RUS84810.1 - 2.5e-15 56.7 0.2 1.2e-14 54.6 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain IBR PF01485.21 RUS84810.1 - 3.5e-12 46.4 40.5 4.7e-07 29.9 3.9 4.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain OB_NTP_bind PF07717.16 RUS84810.1 - 6.2e-12 45.7 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 RUS84810.1 - 4.1e-08 33.5 1.3 1.3e-07 31.9 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 RUS84810.1 - 6.1e-07 29.4 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 RUS84810.1 - 0.00021 21.1 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS84810.1 - 0.00035 20.9 1.1 0.00096 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Nup35_RRM_2 PF14605.6 RUS84810.1 - 0.00089 19.2 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ResIII PF04851.15 RUS84810.1 - 0.0013 18.8 0.8 0.004 17.2 0.0 2.4 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 RUS84810.1 - 0.0032 17.6 10.6 0.97 9.5 4.3 3.4 3 0 0 3 3 3 2 Helicase HerA, central domain RRM_1 PF00076.22 RUS84810.1 - 0.0072 16.1 0.5 0.035 13.9 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RsgA_GTPase PF03193.16 RUS84810.1 - 0.0096 15.8 0.1 0.041 13.8 0.1 2.1 1 0 0 1 1 1 1 RsgA GTPase Helicase_RecD PF05127.14 RUS84810.1 - 0.012 15.4 0.0 0.047 13.5 0.0 2.1 1 0 0 1 1 1 0 Helicase RRM_3 PF08777.11 RUS84810.1 - 0.023 14.8 0.5 0.23 11.5 0.0 3.0 3 0 0 3 3 2 0 RNA binding motif AbiJ_NTD5 PF18865.1 RUS84810.1 - 0.024 14.5 1.9 0.031 14.1 0.2 2.1 2 0 0 2 2 1 0 AbiJ N-terminal domain 5 DUF4482 PF14818.6 RUS84810.1 - 0.046 14.6 0.1 0.046 14.6 0.1 3.1 4 0 0 4 4 2 0 Domain of unknown function (DUF4482) AAA_19 PF13245.6 RUS84810.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS84810.1 - 0.88 10.1 6.6 0.54 10.8 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Peptidase_S46 PF10459.9 RUS84810.1 - 2.1 6.9 11.1 10 4.6 0.2 2.3 2 0 0 2 2 2 0 Peptidase S46 QRPTase_C PF01729.19 RUS84811.1 - 1.6e-55 187.5 0.1 2e-55 187.1 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RUS84811.1 - 2.9e-22 78.5 0.0 6.9e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain L_HMGIC_fpl PF10242.9 RUS84812.1 - 1e-06 29.1 0.7 0.055 13.7 0.0 2.3 2 0 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein TANGO2 PF05742.12 RUS84813.1 - 4e-42 145.0 0.0 7e-39 134.4 0.0 2.2 1 1 1 2 2 2 2 Transport and Golgi organisation 2 AKNA PF12443.8 RUS84815.1 - 0.0021 18.7 1.8 0.0021 18.7 1.8 3.0 2 0 0 2 2 2 1 AT-hook-containing transcription factor OmpH PF03938.14 RUS84815.1 - 0.71 10.2 15.8 1.2 9.4 6.5 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 RUS84815.1 - 2.2 8.9 10.0 2.3 8.8 1.5 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 RUS84816.1 - 0.095 13.1 14.0 0.24 11.8 0.9 2.7 2 0 0 2 2 2 0 Syntaxin-like protein MRP-S23 PF10484.9 RUS84816.1 - 0.11 12.8 1.8 2.8 8.2 0.9 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 TSC22 PF01166.18 RUS84816.1 - 0.11 12.8 9.6 1.4 9.3 0.3 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 RUS84816.1 - 0.28 11.7 26.8 1.6 9.2 4.3 4.5 2 1 2 4 4 4 0 Cell division protein ZapB TTKRSYEDQ PF10212.9 RUS84816.1 - 0.36 9.8 16.8 0.26 10.2 7.4 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein HHA PF05321.11 RUS84816.1 - 0.47 10.8 4.6 7.9 6.9 0.1 3.1 3 0 0 3 3 3 0 Haemolysin expression modulating protein YnfE PF17452.2 RUS84816.1 - 0.65 10.3 4.2 0.22 11.9 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized YnfE-like DUF812 PF05667.11 RUS84816.1 - 0.73 8.6 27.5 2.7 6.8 12.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CdvA PF18822.1 RUS84816.1 - 0.94 9.3 26.6 2.1 8.2 15.8 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 RUS84816.1 - 0.99 9.8 15.9 0.49 10.8 2.9 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 RUS84816.1 - 1.4 6.8 11.1 0.89 7.4 6.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RUS84816.1 - 2.1 8.9 31.4 0.62 10.6 3.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 RUS84816.1 - 3.2 6.2 13.6 7.6 5.0 9.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4298 PF14131.6 RUS84816.1 - 3.3 7.7 8.2 15 5.7 3.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) HALZ PF02183.18 RUS84816.1 - 4.7 7.5 17.6 22 5.4 0.3 4.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Rab5-bind PF09311.11 RUS84817.1 - 4.8e-63 213.4 52.4 4.8e-63 213.4 52.4 5.3 3 2 1 4 4 4 1 Rabaptin-like protein Rabaptin PF03528.15 RUS84817.1 - 8.2e-63 212.8 60.8 9.7e-44 149.9 20.0 4.7 4 2 0 4 4 4 2 Rabaptin FYVE PF01363.21 RUS84817.1 - 8.1e-15 54.7 10.6 8.1e-15 54.7 10.6 2.4 2 0 0 2 2 2 1 FYVE zinc finger IL11 PF07400.11 RUS84817.1 - 0.0048 16.6 1.0 0.0048 16.6 1.0 3.7 3 0 0 3 3 3 1 Interleukin 11 DUF1640 PF07798.11 RUS84817.1 - 0.01 15.9 12.6 0.01 15.9 12.6 6.9 3 3 3 6 6 6 0 Protein of unknown function (DUF1640) IBR PF01485.21 RUS84817.1 - 0.011 16.0 5.9 0.053 13.7 5.9 2.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 RUS84817.1 - 0.034 14.1 2.5 0.099 12.6 2.5 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_2 PF13639.6 RUS84817.1 - 1.9 8.9 8.2 4.9 7.6 8.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-ribbon_3 PF13248.6 RUS84817.1 - 2.3 7.7 6.4 0.15 11.5 1.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Big_9 PF17963.1 RUS84818.1 - 4.1e-05 24.2 0.3 4.1e-05 24.2 0.3 1.7 2 0 0 2 2 2 1 Bacterial Ig domain Cadherin_4 PF17803.1 RUS84818.1 - 8.4e-05 23.1 0.5 0.00018 22.1 0.4 1.7 1 1 0 1 1 1 1 Bacterial cadherin-like domain UFD1 PF03152.14 RUS84819.1 - 7.1e-79 263.3 0.0 8.5e-79 263.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Tenui_PVC2 PF06656.11 RUS84819.1 - 0.025 12.5 0.0 0.034 12.1 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein 7tm_3 PF00003.22 RUS84820.1 - 8.5e-35 120.6 12.9 1.2e-34 120.1 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR His_Phos_2 PF00328.22 RUS84821.1 - 1.9e-98 330.3 2.6 8.8e-98 328.1 2.6 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RUS84821.1 - 4.8e-37 126.0 0.1 9.1e-37 125.1 0.1 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RUS84821.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NYD-SP28 PF14772.6 RUS84822.1 - 1.1e-27 96.0 14.2 1.1e-27 96.0 14.2 4.5 3 1 0 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 RUS84822.1 - 1.8e-09 37.5 20.3 8.9e-09 35.3 4.0 4.4 3 0 0 3 3 3 2 Sperm tail C-terminal domain Baculo_PEP_C PF04513.12 RUS84822.1 - 0.41 10.7 14.2 0.53 10.3 0.8 3.9 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad1 PF08649.10 RUS84822.1 - 5.2 7.3 10.6 5.2 7.3 0.1 4.8 4 0 0 4 4 4 0 DASH complex subunit Dad1 CBM_14 PF01607.24 RUS84823.1 - 2.3e-06 27.7 26.9 0.042 14.0 0.2 6.9 1 1 4 5 5 5 5 Chitin binding Peritrophin-A domain DUF4789 PF16033.5 RUS84823.1 - 3e-05 24.5 26.3 0.00017 22.0 6.4 3.8 1 1 3 4 4 4 2 Domain of unknown function (DUF4789) DUF4789 PF16033.5 RUS84824.1 - 0.00016 22.2 19.4 0.012 16.1 2.0 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4789) CBM_14 PF01607.24 RUS84824.1 - 0.1 12.8 21.4 0.28 11.4 0.3 5.0 3 2 2 5 5 5 0 Chitin binding Peritrophin-A domain Tim17 PF02466.19 RUS84825.1 - 3.1e-25 88.7 8.9 4.3e-25 88.2 8.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 RUS84825.1 - 0.019 14.7 3.3 2.6 7.9 4.7 2.6 2 1 0 2 2 2 0 YMGG-like Gly-zipper Romo1 PF10247.9 RUS84825.1 - 1.5 9.2 15.1 1.8 9.0 2.4 2.8 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 WD40 PF00400.32 RUS84826.1 - 2.1e-19 69.5 4.4 1.6e-07 31.9 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 RUS84826.1 - 0.00015 21.7 0.0 0.22 11.4 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RUS84826.1 - 0.00072 19.8 0.1 1.3 9.4 0.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 RUS84826.1 - 0.037 12.5 0.1 0.098 11.1 0.0 1.5 1 1 0 1 1 1 0 Utp8 family DUF4988 PF16378.5 RUS84826.1 - 0.063 12.9 0.1 0.37 10.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function LapA_dom PF06305.11 RUS84826.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2681 PF10883.8 RUS84826.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Ge1_WD40 PF16529.5 RUS84826.1 - 0.094 11.7 0.0 0.45 9.4 0.0 2.1 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 RUS84826.1 - 0.1 11.7 0.1 7.8 5.4 0.1 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Na_Ca_ex PF01699.24 RUS84827.1 - 2e-30 105.7 16.6 2.5e-30 105.4 16.6 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein SPC25 PF06703.11 RUS84827.1 - 0.24 11.1 2.1 0.46 10.2 2.1 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_hydro_31 PF01055.26 RUS84828.1 - 2.1e-20 73.4 0.0 2.6e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 RUS84828.1 - 0.021 15.1 0.0 0.093 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 RUS84829.1 - 6.1e-53 180.6 1.3 7.7e-53 180.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 RUS84829.1 - 5.9e-23 81.3 0.0 8.7e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 RUS84829.1 - 6.7e-06 26.3 0.2 3.1e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Trefoil PF00088.18 RUS84829.1 - 2.5e-05 24.1 0.7 4.4e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain Abhydro_lipase PF04083.16 RUS84829.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Exo_endo_phos PF03372.23 RUS84830.1 - 7e-18 65.0 0.0 1.3e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SBF PF01758.16 RUS84831.1 - 4.1e-19 69.0 7.0 4.1e-19 69.0 7.0 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family MNHE PF01899.16 RUS84831.1 - 0.0083 15.9 4.0 0.025 14.3 4.0 1.9 1 1 0 1 1 1 1 Na+/H+ ion antiporter subunit DUF21 PF01595.20 RUS84831.1 - 6.2 6.5 8.1 10 5.8 8.1 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF3540 PF12059.8 RUS84833.1 - 7.1e-05 22.7 1.4 3.2 7.5 0.0 4.1 1 1 3 4 4 4 3 Protein of unknown function (DUF3540) DUF3971 PF13116.6 RUS84833.1 - 0.0038 16.9 23.8 8.6 5.8 3.2 7.7 1 1 5 7 7 7 3 Protein of unknown function Toxin_25 PF08095.11 RUS84835.1 - 1.3 9.0 5.0 2.5 8.1 5.0 1.5 1 0 0 1 1 1 0 Hefutoxin family Fibrinogen_BP PF08017.11 RUS84837.1 - 5.5e-15 54.7 3.6 6e-15 54.6 3.6 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein Cornifin PF02389.15 RUS84837.1 - 3.8e-07 30.4 0.1 4.4e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3551 PF12071.8 RUS84837.1 - 5e-05 23.3 29.1 0.21 11.7 3.5 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3551) CRAM_rpt PF07016.11 RUS84837.1 - 0.0012 18.5 16.9 12 5.9 0.2 6.5 1 1 1 2 2 2 1 Cysteine-rich acidic integral membrane protein precursor EpCAM_N PF18635.1 RUS84837.1 - 0.0021 18.2 36.9 0.84 9.8 1.2 5.8 1 1 5 6 6 6 5 Epithelial cell adhesion molecule N-terminal domain Adhesin_Dr PF04619.12 RUS84837.1 - 0.029 14.3 15.1 1.9 8.4 0.4 4.4 1 1 3 4 4 4 0 Dr-family adhesin NACHT_sigma PF17106.5 RUS84837.1 - 0.12 12.6 17.1 7.7 6.7 0.6 5.0 1 1 3 4 4 4 0 Sigma domain on NACHT-NTPases C1_1 PF00130.22 RUS84837.1 - 0.18 11.7 25.9 8.9 6.3 2.2 4.3 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCCH PF00642.24 RUS84837.1 - 0.69 9.9 39.8 4.4 7.3 0.8 7.2 2 2 5 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Homeobox_KN PF05920.11 RUS84838.1 - 3.7e-17 61.9 0.6 5.8e-17 61.3 0.6 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS84838.1 - 2.2e-06 27.4 1.4 3.2e-06 26.9 1.4 1.3 1 0 0 1 1 1 1 Homeodomain BUD22 PF09073.10 RUS84838.1 - 0.00077 18.9 26.2 0.00077 18.9 26.2 2.1 2 0 0 2 2 2 1 BUD22 Spc7 PF08317.11 RUS84841.1 - 4.2e-10 39.0 22.0 5.9e-08 31.9 5.5 4.3 1 1 4 5 5 5 5 Spc7 kinetochore protein DUF1664 PF07889.12 RUS84841.1 - 1.8e-09 37.7 31.9 0.036 14.1 0.9 6.6 2 1 4 6 6 6 5 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 RUS84841.1 - 8.3e-08 32.4 13.2 0.14 12.2 0.3 4.4 2 1 0 4 4 4 3 TPR/MLP1/MLP2-like protein SlyX PF04102.12 RUS84841.1 - 3.3e-07 30.8 5.8 7 7.4 0.2 6.6 3 1 4 7 7 7 0 SlyX Baculo_PEP_C PF04513.12 RUS84841.1 - 6.5e-07 29.5 33.6 0.014 15.5 0.3 5.3 1 1 4 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 RUS84841.1 - 1.5e-06 28.3 24.5 0.0064 16.5 7.5 5.4 2 2 3 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 RUS84841.1 - 8.4e-06 24.2 20.9 8.1e-05 21.0 0.6 4.4 1 1 3 4 4 4 2 Septation ring formation regulator, EzrA GAS PF13851.6 RUS84841.1 - 2.4e-05 23.8 13.8 6.9e-05 22.3 3.6 3.7 2 2 0 3 3 3 1 Growth-arrest specific micro-tubule binding ERM PF00769.19 RUS84841.1 - 2.5e-05 24.2 0.9 2.5e-05 24.2 0.9 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 RUS84841.1 - 2.6e-05 23.3 2.5 2.6e-05 23.3 2.5 3.6 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.22 RUS84841.1 - 3.1e-05 24.2 26.1 0.64 10.3 0.0 6.0 2 2 4 6 6 6 2 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 RUS84841.1 - 3.5e-05 23.7 23.3 0.02 14.8 1.6 5.1 1 1 3 5 5 5 2 Protein of unknown function (DUF724) ATG16 PF08614.11 RUS84841.1 - 4.2e-05 23.9 20.4 0.025 14.8 1.5 4.6 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) Taxilin PF09728.9 RUS84841.1 - 0.0002 20.6 9.1 0.031 13.5 4.1 3.9 3 1 0 3 3 3 1 Myosin-like coiled-coil protein NPV_P10 PF05531.12 RUS84841.1 - 0.00023 21.6 31.5 0.0024 18.3 0.1 8.1 2 2 5 7 7 6 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 RUS84841.1 - 0.00033 20.7 37.5 0.007 16.4 2.0 6.7 2 1 5 8 8 8 2 Laminin Domain II Fez1 PF06818.15 RUS84841.1 - 0.00034 21.1 21.5 0.0051 17.3 6.7 4.2 1 1 1 2 2 2 1 Fez1 KxDL PF10241.9 RUS84841.1 - 0.00037 20.7 16.7 0.84 9.9 1.1 5.6 3 3 2 5 5 5 2 Uncharacterized conserved protein Fib_alpha PF08702.10 RUS84841.1 - 0.00047 20.4 31.2 0.066 13.4 5.4 4.6 2 1 1 4 4 4 3 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 RUS84841.1 - 0.00056 19.7 14.8 0.7 9.6 0.6 4.8 2 1 1 4 4 4 2 Domain of unknown function (DUF4201) DUF948 PF06103.11 RUS84841.1 - 0.00066 19.9 29.2 0.77 10.1 0.6 6.5 2 1 4 7 7 7 2 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.13 RUS84841.1 - 0.00085 18.6 20.7 0.0075 15.5 2.8 4.5 1 1 1 3 3 3 1 HAP1 N-terminal conserved region Filament PF00038.21 RUS84841.1 - 0.00092 18.9 21.5 0.032 13.8 1.8 5.3 1 1 3 5 5 5 1 Intermediate filament protein TolA_bind_tri PF16331.5 RUS84841.1 - 0.00094 19.2 5.7 0.67 10.1 0.0 4.5 4 1 1 5 5 3 1 TolA binding protein trimerisation BLOC1_2 PF10046.9 RUS84841.1 - 0.0011 19.2 22.0 6.8 7.1 0.4 6.9 2 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.11 RUS84841.1 - 0.0013 18.2 19.5 0.0015 18.0 4.3 4.0 3 1 1 4 4 4 1 Rabaptin-like protein IFT57 PF10498.9 RUS84841.1 - 0.0013 17.7 25.8 0.038 13.0 7.3 4.1 2 1 2 4 4 4 2 Intra-flagellar transport protein 57 DUF16 PF01519.16 RUS84841.1 - 0.0014 19.1 25.1 0.74 10.3 1.4 6.3 1 1 4 5 5 5 1 Protein of unknown function DUF16 Tropomyosin_1 PF12718.7 RUS84841.1 - 0.0019 18.4 19.9 0.32 11.1 2.9 4.9 2 1 2 4 4 4 2 Tropomyosin like Snapin_Pallidin PF14712.6 RUS84841.1 - 0.0032 17.9 16.9 0.14 12.6 0.8 5.8 3 2 3 6 6 6 2 Snapin/Pallidin YscO-like PF16789.5 RUS84841.1 - 0.0041 17.2 3.2 0.0041 17.2 3.2 2.6 2 0 0 2 2 2 1 YscO-like protein DivIC PF04977.15 RUS84841.1 - 0.0044 16.7 15.5 0.77 9.6 0.0 5.6 6 1 0 6 6 4 1 Septum formation initiator COG2 PF06148.11 RUS84841.1 - 0.0066 16.5 25.9 0.71 10.0 1.3 6.5 3 2 3 6 6 6 2 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 RUS84841.1 - 0.007 16.5 23.0 0.092 12.8 0.3 5.3 2 2 2 4 4 4 1 Afadin- and alpha -actinin-Binding Prominin PF05478.11 RUS84841.1 - 0.007 14.4 25.4 0.0049 14.9 9.5 2.8 1 1 1 2 2 2 1 Prominin ZapB PF06005.12 RUS84841.1 - 0.008 16.6 9.6 3.9 8.0 0.0 4.9 4 1 0 5 5 4 0 Cell division protein ZapB DUF4472 PF14739.6 RUS84841.1 - 0.013 16.2 18.5 5.9 7.7 0.7 5.3 2 1 4 6 6 6 0 Domain of unknown function (DUF4472) Tropomyosin PF00261.20 RUS84841.1 - 0.014 14.8 15.5 0.065 12.6 1.4 4.2 2 1 0 3 3 3 0 Tropomyosin CorA PF01544.18 RUS84841.1 - 0.015 14.7 16.3 0.53 9.5 0.5 4.0 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein CtIP_N PF10482.9 RUS84841.1 - 0.017 15.2 9.3 0.65 10.1 0.1 4.0 3 1 0 4 4 3 0 Tumour-suppressor protein CtIP N-terminal domain Vps51 PF08700.11 RUS84841.1 - 0.018 15.1 15.4 1.4 9.0 0.0 6.5 5 2 2 8 8 5 0 Vps51/Vps67 DUF3450 PF11932.8 RUS84841.1 - 0.018 14.3 18.2 0.91 8.8 0.1 5.2 2 1 4 6 6 6 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 RUS84841.1 - 0.021 14.1 19.9 0.16 11.2 0.8 4.6 2 1 4 6 6 6 0 TMPIT-like protein Tup_N PF08581.10 RUS84841.1 - 0.023 15.0 14.8 10 6.5 0.1 6.7 5 2 3 8 8 8 0 Tup N-terminal DUF745 PF05335.13 RUS84841.1 - 0.028 14.1 15.4 0.14 11.9 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF745) Uds1 PF15456.6 RUS84841.1 - 0.034 14.3 20.1 0.66 10.1 0.7 4.9 3 2 0 3 3 3 0 Up-regulated During Septation PI3K_P85_iSH2 PF16454.5 RUS84841.1 - 0.046 13.3 16.4 0.27 10.8 2.5 5.3 2 2 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec34 PF04136.15 RUS84841.1 - 0.048 13.5 29.4 1.2 9.0 0.9 7.0 3 2 5 8 8 8 0 Sec34-like family YabA PF06156.13 RUS84841.1 - 0.071 13.7 17.7 2.1 9.1 0.9 6.5 3 2 3 6 6 6 0 Initiation control protein YabA CCDC144C PF14915.6 RUS84841.1 - 0.072 12.2 23.9 0.44 9.6 0.9 4.7 2 1 3 5 5 5 0 CCDC144C protein coiled-coil region LPP PF04728.13 RUS84841.1 - 0.079 13.4 34.0 0.19 12.1 0.5 9.0 5 2 2 7 7 6 0 Lipoprotein leucine-zipper Lebercilin PF15619.6 RUS84841.1 - 0.081 12.6 15.8 2.1 8.0 3.4 4.5 2 2 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease HrpB7 PF09486.10 RUS84841.1 - 0.093 13.1 0.9 18 5.7 0.1 3.7 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) APG6_N PF17675.1 RUS84841.1 - 0.1 13.2 12.8 0.15 12.5 1.2 4.3 2 2 1 4 4 4 0 Apg6 coiled-coil region DUF2730 PF10805.8 RUS84841.1 - 0.11 12.6 13.3 4.9 7.3 0.5 5.5 3 3 3 6 6 5 0 Protein of unknown function (DUF2730) Flt3_lig PF02947.14 RUS84841.1 - 0.15 12.2 3.6 0.27 11.4 0.0 3.2 4 0 0 4 4 1 0 flt3 ligand YscO PF07321.12 RUS84841.1 - 0.2 11.6 5.3 7.5 6.5 0.1 4.2 5 0 0 5 5 3 0 Type III secretion protein YscO DUF4763 PF15960.5 RUS84841.1 - 0.23 10.7 10.1 0.7 9.1 0.8 3.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4763) Prefoldin_2 PF01920.20 RUS84841.1 - 0.23 11.4 15.9 10 6.1 0.4 5.5 3 1 2 5 5 4 0 Prefoldin subunit Vps53_N PF04100.12 RUS84841.1 - 0.29 10.0 23.8 0.041 12.9 0.9 3.5 3 1 0 4 4 3 0 Vps53-like, N-terminal BDV_P24 PF06595.11 RUS84841.1 - 0.44 10.4 4.0 1.3 8.8 0.5 2.8 1 1 2 3 3 2 0 Borna disease virus P24 protein DUF2935 PF11155.8 RUS84841.1 - 0.48 10.8 16.9 2.6 8.4 1.1 5.1 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) CEP209_CC5 PF16574.5 RUS84841.1 - 0.6 10.3 17.8 0.5 10.5 3.3 3.3 4 0 0 4 4 2 0 Coiled-coil region of centrosome protein CE290 DUF4200 PF13863.6 RUS84841.1 - 0.62 10.5 11.3 29 5.1 2.0 4.6 2 1 4 6 6 6 0 Domain of unknown function (DUF4200) LOH1CR12 PF10158.9 RUS84841.1 - 0.96 9.5 9.1 7.7 6.6 0.0 4.5 1 1 2 4 4 4 0 Tumour suppressor protein DASH_Dam1 PF08653.10 RUS84841.1 - 1.2 9.0 8.2 6 6.7 0.3 5.1 3 1 3 6 6 5 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 RUS84841.1 - 1.3 9.6 24.3 1.1 9.9 0.2 5.7 2 2 2 5 5 5 0 Syntaxin 6, N-terminal XhlA PF10779.9 RUS84841.1 - 1.4 9.2 28.5 5.3 7.3 1.0 7.0 7 1 1 8 8 8 0 Haemolysin XhlA KASH_CCD PF14662.6 RUS84841.1 - 1.4 8.7 22.0 0.43 10.4 8.8 4.2 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH FliJ PF02050.16 RUS84841.1 - 1.6 9.0 8.7 2.7 8.2 0.2 4.3 4 1 1 5 5 4 0 Flagellar FliJ protein Nsp1_C PF05064.13 RUS84841.1 - 1.7 8.5 15.1 5.8 6.7 0.4 4.9 3 2 2 5 5 4 0 Nsp1-like C-terminal region MscS_porin PF12795.7 RUS84841.1 - 1.8 8.1 12.3 9.2 5.7 0.7 4.2 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain Occludin_ELL PF07303.13 RUS84841.1 - 1.9 9.3 12.5 28 5.5 0.1 5.3 3 2 3 6 6 5 0 Occludin homology domain GCN5L1 PF06320.13 RUS84841.1 - 2.2 8.5 13.0 0.91 9.7 0.1 4.6 4 1 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) KELK PF15796.5 RUS84841.1 - 2.4 8.7 4.8 64 4.1 0.3 4.3 3 1 1 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Jnk-SapK_ap_N PF09744.9 RUS84841.1 - 2.5 8.3 19.9 27 5.0 0.4 4.6 2 1 0 4 4 4 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 RUS84841.1 - 3.8 7.6 29.2 1.9 8.6 1.5 6.0 6 0 0 6 6 5 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 RUS84841.1 - 4.5 7.9 12.8 28 5.4 0.0 5.1 3 3 1 5 5 3 0 Bone marrow stromal antigen 2 CLZ PF16526.5 RUS84841.1 - 5.7 7.4 15.5 44 4.5 0.5 6.7 4 1 3 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FH2 PF02181.23 RUS84841.1 - 5.9 5.9 21.9 1.8 7.6 2.4 4.0 2 1 2 4 4 4 0 Formin Homology 2 Domain zf-C4H2 PF10146.9 RUS84841.1 - 7 6.9 21.7 1.7 8.9 6.4 3.6 1 1 0 3 3 3 0 Zinc finger-containing protein Atg14 PF10186.9 RUS84841.1 - 7 5.6 24.7 0.99 8.4 7.5 4.1 1 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 RUS84841.1 - 7.5 6.6 15.6 20 5.2 8.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 RUS84841.1 - 7.6 7.0 37.5 5.6 7.4 0.2 9.0 5 2 5 10 10 9 0 Flagella accessory protein C (FlaC) JmjC PF02373.22 RUS84842.1 - 1.9e-18 66.9 0.1 6.7e-18 65.2 0.1 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RUS84842.1 - 1.8e-15 57.4 0.0 6e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Cupin-like domain MRP-L46 PF11788.8 RUS84842.1 - 0.015 16.0 1.5 9.5 7.0 0.1 2.9 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Dynein_attach_N PF15867.5 RUS84844.1 - 1.8e-25 88.6 0.1 3.5e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 RUS84844.1 - 4.1e-15 56.1 0.4 1.1e-14 54.7 0.1 1.8 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 DUF4529 PF15032.6 RUS84844.1 - 0.00079 18.7 0.9 0.00094 18.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4529) Gypsy PF07253.11 RUS84844.1 - 0.12 10.9 0.0 0.22 10.0 0.0 1.4 1 0 0 1 1 1 0 Gypsy protein DUF2247 PF10004.9 RUS84844.1 - 0.43 10.3 2.8 0.67 9.7 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Lactamase_B_6 PF16661.5 RUS84845.1 - 1e-13 51.2 0.2 5.5e-12 45.5 0.0 2.8 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 RUS84845.1 - 8.1e-06 26.1 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 RUS84845.1 - 0.00028 20.2 0.0 0.00049 19.4 0.0 1.4 1 1 0 1 1 1 1 Putative beta-lactamase-like family Actin PF00022.19 RUS84846.1 - 9.8e-63 212.2 0.0 1.6e-28 99.5 0.0 3.0 2 1 0 3 3 3 3 Actin MreB_Mbl PF06723.13 RUS84846.1 - 0.0043 15.9 0.0 0.66 8.7 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 RUS84846.1 - 0.0057 17.1 0.0 0.019 15.3 0.0 1.9 2 1 0 2 2 2 1 Cell division protein FtsA 2H-phosphodiest PF08975.10 RUS84847.1 - 6.1e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1868) SAM_2 PF07647.17 RUS84847.1 - 0.035 14.2 0.0 0.39 10.8 0.0 2.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Arfaptin PF06456.13 RUS84848.1 - 8e-80 267.7 14.6 9.2e-80 267.5 14.6 1.0 1 0 0 1 1 1 1 Arfaptin-like domain Peptidase_C47 PF05543.13 RUS84848.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 DUF1612 PF07756.12 RUS84848.1 - 0.071 13.4 1.0 0.18 12.1 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1612) DUF4446 PF14584.6 RUS84848.1 - 0.39 10.7 9.3 0.3 11.1 0.8 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) BAR_2 PF10455.9 RUS84848.1 - 0.47 9.5 10.7 0.14 11.2 3.9 2.2 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking PAPA-1 PF04795.12 RUS84848.1 - 6.2 7.7 7.3 0.27 12.1 0.3 2.3 2 1 1 3 3 3 0 PAPA-1-like conserved region ICA69 PF04629.14 RUS84849.1 - 3.1e-35 122.7 10.8 1.9e-23 84.1 2.3 3.9 4 0 0 4 4 4 3 Islet cell autoantigen ICA69, C-terminal domain Rsm22 PF09243.10 RUS84849.1 - 0.14 11.4 0.0 16 4.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 RlaP PF10127.9 RUS84850.1 - 4.5e-12 46.1 0.0 7.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 RUS84850.1 - 4.2e-05 23.7 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 RUS84850.1 - 0.013 15.6 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase Dpy-30 PF05186.13 RUS84851.1 - 0.0013 18.4 0.0 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 Dpy-30 motif DUF5586 PF17824.1 RUS84851.1 - 0.0022 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) RIIa PF02197.17 RUS84851.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit TetR_C_19 PF17924.1 RUS84851.1 - 0.14 12.8 0.0 0.69 10.5 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain zf-RING_UBOX PF13445.6 RUS84852.1 - 3e-08 33.6 1.6 3e-08 33.6 1.6 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS84852.1 - 7.5e-07 28.9 3.3 7.5e-07 28.9 3.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS84852.1 - 7.5e-07 29.4 7.0 7.5e-07 29.4 7.0 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RUS84852.1 - 2.5e-05 24.1 4.5 2.5e-05 24.1 4.5 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS84852.1 - 0.00018 21.3 12.4 0.0052 16.6 9.3 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS84852.1 - 0.0012 18.7 4.8 0.0012 18.7 4.8 3.1 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS84852.1 - 0.0033 17.2 10.7 0.013 15.3 3.3 3.4 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS84852.1 - 0.0071 16.5 2.9 0.0071 16.5 2.9 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 RUS84852.1 - 0.16 11.3 0.8 0.21 10.9 0.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FYVE PF01363.21 RUS84852.1 - 0.21 11.7 6.1 0.31 11.2 4.5 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_6 PF14835.6 RUS84852.1 - 0.31 10.9 4.9 0.13 12.2 1.3 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 RUS84853.1 - 8.2e-08 32.2 1.0 8.2e-08 32.2 1.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS84853.1 - 1.1e-06 28.4 5.1 3.6e-06 26.8 4.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS84853.1 - 2.6e-06 27.2 4.0 2.6e-06 27.2 4.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS84853.1 - 3.5e-05 24.0 8.7 0.00016 21.9 8.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS84853.1 - 0.00017 21.5 4.5 0.00048 20.0 4.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS84853.1 - 0.0053 16.6 4.0 0.0053 16.6 4.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS84853.1 - 0.011 15.9 2.5 0.011 15.9 2.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 RUS84853.1 - 0.014 15.2 0.6 0.19 11.6 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 RUS84853.1 - 0.019 14.8 3.5 0.019 14.8 3.5 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 RUS84853.1 - 0.077 12.9 2.6 0.19 11.6 1.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.21 RUS84853.1 - 0.17 12.0 8.6 0.081 13.1 6.1 1.8 2 0 0 2 2 1 0 FYVE zinc finger zf-RING_10 PF16685.5 RUS84853.1 - 0.54 10.4 8.2 0.096 12.8 3.6 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zf_RING PF16744.5 RUS84853.1 - 0.54 10.4 3.9 0.23 11.6 0.9 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger dUTPase PF00692.19 RUS84854.1 - 9.4e-44 148.2 0.0 1.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF4573 PF15140.6 RUS84855.1 - 0.00071 19.4 0.0 4.5 7.0 0.0 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) EB PF01683.18 RUS84857.1 - 1.1 9.6 8.2 2.4 8.5 8.2 1.6 1 0 0 1 1 1 0 EB module NCE101 PF11654.8 RUS84858.1 - 0.011 15.5 25.2 1.8 8.4 0.1 6.6 8 0 0 8 8 8 0 Non-classical export protein 1 7tm_1 PF00001.21 RUS84859.1 - 7.4e-17 61.5 19.9 9.6e-17 61.2 19.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS84859.1 - 0.00028 20.3 10.5 0.00028 20.3 10.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS84859.1 - 0.00041 20.1 14.8 0.0014 18.3 12.3 2.8 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Gln-synt_C PF00120.24 RUS84860.1 - 4.4e-11 42.4 0.0 7e-05 22.0 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain EutN_CcmL PF03319.13 RUS84862.1 - 0.0032 18.0 0.1 45 4.7 0.0 4.0 2 2 2 4 4 4 2 Ethanolamine utilisation protein EutN/carboxysome KA1 PF02149.19 RUS84862.1 - 0.12 12.2 0.1 59 3.6 0.0 3.3 4 0 0 4 4 4 0 Kinase associated domain 1 GTP_EFTU PF00009.27 RUS84863.1 - 3.1e-21 75.8 0.1 4.8e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RUS84863.1 - 2.2e-14 53.7 0.0 5.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RUS84863.1 - 5e-07 30.0 2.1 1.1e-06 29.0 2.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Cullin PF00888.22 RUS84864.1 - 8.6e-30 103.9 2.4 8.6e-30 103.9 2.4 1.8 2 0 0 2 2 2 1 Cullin family FeoC PF09012.10 RUS84864.1 - 0.029 14.4 0.1 0.078 13.1 0.1 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator ING PF12998.7 RUS84864.1 - 0.55 10.8 2.8 0.5 11.0 0.4 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-TRAF PF02176.18 RUS84865.1 - 1.1e-16 61.3 27.5 1.7e-11 44.6 7.7 3.3 3 1 0 3 3 2 2 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 RUS84865.1 - 6.1e-07 29.5 3.5 6.1e-07 29.5 3.5 3.8 4 1 1 5 5 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RUS84865.1 - 1.1e-05 25.2 7.0 1.1e-05 25.2 7.0 3.5 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf_C2HC_14 PF18574.1 RUS84865.1 - 4.6e-05 23.1 0.3 4.6e-05 23.1 0.3 3.5 4 0 0 4 4 2 1 C2HC Zing finger domain zf-C3HC4_2 PF13923.6 RUS84865.1 - 0.00013 21.7 5.8 0.00013 21.7 5.8 3.6 5 1 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS84865.1 - 0.00024 21.1 4.2 0.00024 21.1 4.2 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS84865.1 - 0.0017 18.2 7.6 0.0017 18.2 7.6 4.3 3 1 1 4 4 1 1 Zinc finger, C3HC4 type (RING finger) TRAF_BIRC3_bd PF16673.5 RUS84865.1 - 0.0027 17.5 1.1 0.21 11.4 0.2 2.4 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain zf-DNA_Pol PF08996.10 RUS84865.1 - 0.0029 17.4 1.6 0.0029 17.4 1.6 3.1 1 1 1 2 2 2 1 DNA Polymerase alpha zinc finger zf-RING_5 PF14634.6 RUS84865.1 - 0.0036 17.2 7.4 0.0036 17.2 7.4 4.3 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS84865.1 - 0.005 17.1 8.4 0.005 17.1 8.4 3.7 3 1 1 4 4 1 1 Ring finger domain zf-RING_10 PF16685.5 RUS84865.1 - 0.012 15.7 5.4 0.012 15.7 5.4 2.9 3 1 0 3 3 1 0 zinc RING finger of MSL2 zf-C2HE PF16278.5 RUS84865.1 - 0.036 14.5 10.9 0.73 10.3 1.6 3.8 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_13 PF18508.1 RUS84865.1 - 0.049 13.2 16.6 0.23 11.1 0.9 4.3 4 0 0 4 4 4 0 Zinc finger domain Lebercilin PF15619.6 RUS84865.1 - 0.064 12.9 11.1 1.5 8.5 0.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 RUS84865.1 - 0.1 12.1 5.9 0.17 11.4 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 RUS84865.1 - 0.32 11.2 3.7 0.38 11.0 0.9 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF4094 PF13334.6 RUS84865.1 - 0.68 10.4 5.8 3.2 8.2 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) zf-BED PF02892.15 RUS84865.1 - 0.69 10.0 0.1 0.69 10.0 0.1 4.1 3 1 1 4 4 4 0 BED zinc finger DHR10 PF18595.1 RUS84865.1 - 0.79 9.8 12.4 5.1 7.2 6.8 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DASH_Spc34 PF08657.10 RUS84865.1 - 0.8 9.4 7.1 2.4 7.9 7.1 1.6 1 1 0 1 1 1 0 DASH complex subunit Spc34 EMP24_GP25L PF01105.24 RUS84865.1 - 0.81 9.6 2.9 1.9 8.4 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ABC_tran_CTD PF16326.5 RUS84865.1 - 1 9.7 8.3 2.9 8.2 0.1 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Med9 PF07544.13 RUS84865.1 - 1.3 9.2 7.8 0.47 10.6 2.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4140 PF13600.6 RUS84865.1 - 3.3 8.2 6.4 27 5.3 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DM PF00751.18 RUS84865.1 - 3.7 7.5 20.0 1.1 9.2 4.4 4.0 2 1 1 3 3 3 0 DM DNA binding domain Spc24 PF08286.11 RUS84865.1 - 4.1 7.7 5.6 6.6 7.0 1.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-Nse PF11789.8 RUS84865.1 - 4.2 7.3 10.0 0.34 10.7 1.9 2.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Mod_r PF07200.13 RUS84865.1 - 6.5 6.9 10.7 8.6 6.5 5.6 2.5 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf_UBZ PF18439.1 RUS84865.1 - 7.9 6.2 16.3 11 5.8 0.3 4.9 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger SRAP PF02586.14 RUS84866.1 - 4.6e-61 206.1 0.2 7.6e-36 123.7 0.0 2.4 2 0 0 2 2 2 2 SOS response associated peptidase (SRAP) Mnd1 PF03962.15 RUS84866.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Mnd1 HTH domain Kelch_4 PF13418.6 RUS84867.1 - 1.2e-36 124.5 3.7 3e-09 36.7 0.0 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS84867.1 - 7.5e-35 118.4 1.7 9.4e-06 25.5 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RUS84867.1 - 1e-28 98.6 2.2 3.6e-06 27.1 0.0 5.3 3 2 2 5 5 5 5 Kelch motif Kelch_3 PF13415.6 RUS84867.1 - 6.4e-28 96.5 7.1 3.8e-05 23.9 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS84867.1 - 1.4e-25 88.2 8.1 1.4e-07 31.2 0.1 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 RUS84867.1 - 1.6e-23 82.0 3.3 1.4e-05 24.6 0.0 6.0 5 1 0 5 5 5 5 Kelch motif PQQ_3 PF13570.6 RUS84867.1 - 0.089 13.3 0.0 0.66 10.5 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain 7tm_1 PF00001.21 RUS84868.1 - 6.6e-08 32.2 0.0 7.6e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Methyltransf_12 PF08242.12 RUS84869.1 - 3.4e-15 56.6 0.0 1.4e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS84869.1 - 4.6e-13 49.7 0.0 9.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS84869.1 - 5.7e-13 49.0 0.0 7.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS84869.1 - 1e-10 42.1 0.0 2.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS84869.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS84869.1 - 0.00015 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 RUS84869.1 - 0.0058 16.1 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 RUS84869.1 - 0.022 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 FmrO PF07091.11 RUS84869.1 - 0.031 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) E2_bind PF08825.10 RUS84870.1 - 0.0076 16.4 0.1 3.4 7.9 0.0 2.8 2 1 1 3 3 3 2 E2 binding domain DIRP PF06584.13 RUS84870.1 - 0.023 14.9 1.9 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 DIRP Zip PF02535.22 RUS84871.1 - 5.1e-59 200.1 5.8 6e-59 199.9 5.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter LANC_like PF05147.13 RUS84872.1 - 2.5e-80 269.7 0.0 6.9e-80 268.3 0.0 1.6 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.13 RUS84872.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 RUS84872.1 - 0.17 11.3 0.6 2.5 7.6 0.2 2.4 2 1 1 3 3 3 0 D-glucuronyl C5-epimerase C-terminus F-box PF00646.33 RUS84873.1 - 0.072 13.0 0.2 0.35 10.8 0.2 2.2 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 RUS84873.1 - 0.11 12.4 0.4 0.44 10.4 0.1 2.0 1 1 1 2 2 2 0 F-box Nop16 PF09420.10 RUS84874.1 - 2.6e-20 73.4 9.0 1.2e-13 51.6 0.5 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 THEG PF14912.6 RUS84875.1 - 9e-43 144.5 16.5 4.2e-14 52.7 0.4 5.1 3 1 2 5 5 5 5 Testicular haploid expressed repeat OTU PF02338.19 RUS84876.1 - 2.1e-07 31.5 0.0 3.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 RUS84876.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Folate_carrier PF01770.18 RUS84876.1 - 0.23 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier zf-CpG_bind_C PF12269.8 RUS84877.1 - 8.9e-98 326.7 10.7 8.9e-98 326.7 10.7 2.2 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain zf-CXXC PF02008.20 RUS84877.1 - 9.1e-15 54.4 22.5 9.1e-15 54.4 22.5 4.0 5 0 0 5 5 5 1 CXXC zinc finger domain PHD PF00628.29 RUS84877.1 - 1.3e-11 44.2 6.9 1.3e-11 44.2 6.9 4.3 4 0 0 4 4 4 1 PHD-finger Pepsin-I3 PF06394.13 RUS84877.1 - 0.003 17.7 0.9 0.008 16.4 0.9 1.7 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain zf-H2C2_2 PF13465.6 RUS84878.1 - 1e-62 205.9 128.3 3.3e-07 30.4 1.8 18.2 19 0 0 19 19 18 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS84878.1 - 4.3e-51 167.1 137.9 0.0023 18.6 1.8 18.2 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS84878.1 - 9.1e-50 164.4 139.7 9.6e-05 22.6 1.2 18.4 18 0 0 18 18 18 16 Zinc finger, C2H2 type zf-met PF12874.7 RUS84878.1 - 1.4e-18 66.6 107.1 0.02 15.2 1.0 18.1 18 0 0 18 18 18 10 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS84878.1 - 3.6e-15 55.8 74.1 0.018 15.4 0.9 16.6 18 0 0 18 18 17 7 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS84878.1 - 8.1e-10 38.3 89.2 0.059 13.1 0.2 14.4 15 0 0 15 15 14 8 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RUS84878.1 - 6.8e-08 32.3 149.0 0.041 13.9 5.5 20.1 19 3 0 19 19 18 11 C2H2-type zinc finger zf-C2HE PF16278.5 RUS84878.1 - 1.7e-07 31.6 89.5 0.062 13.8 2.0 13.0 5 4 8 13 13 13 6 C2HE / C2H2 / C2HC zinc-binding finger Exog_C PF18026.1 RUS84878.1 - 5.7e-05 23.1 0.0 0.63 10.1 0.0 2.5 2 0 0 2 2 2 2 Endo/exonuclease (EXOG) C-terminal domain zf-Di19 PF05605.12 RUS84878.1 - 0.00044 20.5 93.0 0.14 12.5 4.1 10.6 6 3 5 11 11 11 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 RUS84878.1 - 0.0067 16.7 66.7 0.016 15.5 5.0 8.2 2 2 7 9 9 9 6 C2H2-type zinc ribbon TBCC PF07986.12 RUS84878.1 - 0.036 13.8 4.9 1.3 8.8 0.5 3.4 2 2 0 2 2 2 0 Tubulin binding cofactor C CpXC PF14353.6 RUS84878.1 - 0.039 14.0 53.7 0.62 10.1 0.2 11.5 4 3 9 13 13 13 0 CpXC protein DUF3268 PF11672.8 RUS84878.1 - 0.069 13.5 0.2 0.069 13.5 0.2 8.0 8 1 1 9 9 9 0 zinc-finger-containing domain Ta0938 PF11494.8 RUS84878.1 - 0.45 10.8 30.4 0.38 11.1 0.2 8.3 2 2 6 10 10 10 0 Ta0938 Zn-ribbon_8 PF09723.10 RUS84878.1 - 3.4 7.9 68.4 3.3 7.9 1.9 11.7 10 4 2 12 12 12 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 RUS84878.1 - 3.8 7.9 85.3 0.24 11.8 0.7 11.5 1 1 10 11 11 10 0 C2H2 type zinc-finger (2 copies) Cript PF10235.9 RUS84878.1 - 4.3 8.0 70.7 0.25 11.9 5.7 10.2 2 2 7 9 9 9 0 Microtubule-associated protein CRIPT C1_2 PF03107.16 RUS84878.1 - 4.8 7.6 90.7 0.37 11.1 5.6 15.0 5 4 7 13 13 13 0 C1 domain 6PF2K PF01591.18 RUS84879.1 - 1.1e-30 106.6 0.1 1.5e-30 106.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 RUS84879.1 - 0.003 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 RUS84879.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 RUS84879.1 - 0.058 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin zf-met PF12874.7 RUS84879.1 - 0.098 13.1 0.3 0.28 11.6 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Tir_receptor_C PF07489.11 RUS84879.1 - 2.1 8.3 8.1 3.3 7.6 8.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus 6PF2K PF01591.18 RUS84880.1 - 8.5e-61 205.1 2.6 1.2e-60 204.6 2.6 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RUS84880.1 - 1.2e-42 145.8 0.0 2.2e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RUS84880.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Str_synth PF03088.16 RUS84882.1 - 4.9e-20 71.5 0.0 1.6e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 RUS84882.1 - 5e-10 39.4 0.0 1.1e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 RUS84882.1 - 0.11 13.1 0.0 4 8.0 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain Sulfotransfer_1 PF00685.27 RUS84884.1 - 0.00011 21.7 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS84884.1 - 0.00013 22.4 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family FKS1_dom1 PF14288.6 RUS84884.1 - 0.036 14.4 0.1 0.044 14.1 0.1 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Sulfotransfer_3 PF13469.6 RUS84885.1 - 0.00011 22.6 0.0 0.00027 21.4 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family DUF1943 PF09172.11 RUS84887.1 - 0.024 13.9 0.5 0.042 13.1 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) LEA_2 PF03168.13 RUS84887.1 - 0.42 11.2 14.8 8.6 7.0 6.4 2.7 1 1 1 2 2 2 0 Late embryogenesis abundant protein Sulfotransfer_1 PF00685.27 RUS84888.1 - 2.2e-15 56.9 1.2 5.7e-15 55.5 1.2 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS84888.1 - 8.3e-15 55.8 0.3 1.9e-14 54.6 0.3 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 RUS84888.1 - 0.03 14.1 0.0 0.079 12.8 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase domain DUF5304 PF17230.2 RUS84888.1 - 0.19 12.0 0.0 0.45 10.7 0.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5304) Ninjurin PF04923.12 RUS84889.1 - 5.2e-22 77.7 3.9 8e-22 77.1 3.9 1.3 1 0 0 1 1 1 1 Ninjurin AA_permease_2 PF13520.6 RUS84889.1 - 0.0059 15.5 0.3 1.5 7.5 0.1 2.0 2 0 0 2 2 2 2 Amino acid permease DUF485 PF04341.12 RUS84889.1 - 0.012 15.6 0.8 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF1751 PF08551.10 RUS84889.1 - 0.087 13.4 3.3 0.25 11.9 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) MPS-4 PF17523.2 RUS84889.1 - 0.11 12.6 3.4 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DHHC PF01529.20 RUS84889.1 - 0.11 12.6 1.5 0.22 11.7 1.5 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF1003 PF06210.11 RUS84889.1 - 0.16 12.1 0.2 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Orf78 PF06024.12 RUS84889.1 - 0.46 10.8 2.3 2.9 8.3 0.3 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Sigma_reg_N PF13800.6 RUS84889.1 - 1.1 9.6 4.4 19 5.7 0.3 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Sugar_tr PF00083.24 RUS84890.1 - 2e-23 83.0 5.6 3.3e-23 82.3 5.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS84890.1 - 1.9e-14 53.4 8.7 1.9e-14 53.4 8.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 RUS84890.1 - 0.00039 19.8 3.4 0.00055 19.3 3.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 RUS84891.1 - 2.8e-29 102.3 21.0 2.8e-29 102.3 21.0 1.8 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS84891.1 - 1.1e-19 70.6 45.1 1.1e-13 50.9 22.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Amidase_2 PF01510.25 RUS84892.1 - 3.2e-22 79.3 0.0 4.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase DUF393 PF04134.12 RUS84893.1 - 1.3e-18 68.3 0.0 2e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Hydrolase_6 PF13344.6 RUS84894.1 - 1.1e-21 76.8 0.0 2e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RUS84894.1 - 0.096 12.8 0.0 7.6 6.7 0.0 2.6 2 1 0 2 2 2 0 HAD-hyrolase-like CIMR PF00878.18 RUS84895.1 - 4.1e-07 30.2 1.2 0.03 14.4 0.0 2.5 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Ephrin_rec_like PF07699.13 RUS84895.1 - 0.015 15.0 0.9 0.015 15.0 0.9 9.3 6 3 5 11 11 11 0 Putative ephrin-receptor like NCD3G PF07562.14 RUS84895.1 - 0.13 12.2 59.0 0.05 13.6 3.1 7.9 6 2 1 8 8 7 0 Nine Cysteines Domain of family 3 GPCR Tmemb_55A PF09788.9 RUS84895.1 - 0.29 10.2 9.7 0.015 14.4 1.6 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A TNFR_c6 PF00020.18 RUS84895.1 - 0.61 10.5 0.1 0.61 10.5 0.1 9.4 7 2 1 9 9 9 0 TNFR/NGFR cysteine-rich region Bax1-I PF01027.20 RUS84896.1 - 4e-51 173.8 25.2 4.6e-51 173.6 25.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4079 PF13301.6 RUS84896.1 - 0.69 10.1 13.0 2.4 8.3 12.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2070 PF09843.9 RUS84896.1 - 2 6.6 16.8 2.6 6.2 16.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase_Tyr PF07714.17 RUS84897.1 - 4.5e-35 121.2 0.1 3.9e-21 75.5 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS84897.1 - 2e-11 43.8 9.4 1.1e-05 25.0 0.0 3.0 2 1 1 3 3 2 2 Protein kinase domain Ephrin_rec_like PF07699.13 RUS84897.1 - 2.3e-05 24.0 29.9 0.00015 21.5 8.1 3.5 3 0 0 3 3 3 2 Putative ephrin-receptor like Syndecan PF01034.20 RUS84897.1 - 0.00068 19.5 4.6 0.34 10.9 0.2 2.8 1 1 1 2 2 2 2 Syndecan domain DUF1387 PF07139.11 RUS84897.1 - 0.0023 17.8 10.8 0.0023 17.8 10.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) LPG_synthase_TM PF03706.13 RUS84897.1 - 0.0067 16.0 0.9 0.012 15.2 0.9 1.3 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region FecCD PF01032.18 RUS84897.1 - 0.04 12.9 0.9 0.061 12.3 0.9 1.2 1 0 0 1 1 1 0 FecCD transport family VIT1 PF01988.19 RUS84897.1 - 0.062 13.2 0.3 0.062 13.2 0.3 1.9 2 0 0 2 2 2 0 VIT family DUF4962 PF16332.5 RUS84897.1 - 0.53 8.7 0.0 0.53 8.7 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4962) DUF347 PF03988.12 RUS84897.1 - 1.3 9.3 4.1 27 5.0 0.3 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) FixQ PF05545.11 RUS84897.1 - 1.6 8.8 3.2 31 4.6 0.2 2.6 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ YrhC PF14143.6 RUS84897.1 - 2.7 8.1 4.7 28 4.9 0.4 2.5 1 1 1 2 2 2 0 YrhC-like protein DUF2052 PF09747.9 RUS84899.1 - 0.001 19.3 16.9 0.0019 18.3 16.9 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF5523 PF17661.1 RUS84899.1 - 0.0043 16.8 18.4 0.0077 16.0 18.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Nop14 PF04147.12 RUS84899.1 - 0.0048 15.2 20.8 0.006 14.9 20.8 1.1 1 0 0 1 1 1 1 Nop14-like family PPP4R2 PF09184.11 RUS84899.1 - 0.0084 15.7 21.9 0.014 15.1 21.9 1.3 1 0 0 1 1 1 1 PPP4R2 Sigma70_ner PF04546.13 RUS84899.1 - 0.018 14.9 18.2 0.028 14.3 18.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.12 RUS84899.1 - 0.024 13.1 22.4 0.036 12.5 22.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Merozoite_SPAM PF07133.11 RUS84899.1 - 0.027 14.5 40.7 0.047 13.7 40.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC27 PF09507.10 RUS84899.1 - 0.031 13.7 13.7 0.056 12.8 13.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 RUS84899.1 - 0.077 12.3 17.1 0.13 11.6 17.1 1.4 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 RUS84899.1 - 0.083 13.6 14.9 0.22 12.2 14.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 RUS84899.1 - 0.12 10.5 34.2 0.17 10.0 34.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 RUS84899.1 - 0.42 9.3 12.9 0.97 8.2 12.9 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.13 RUS84899.1 - 0.49 9.3 28.4 0.039 13.0 22.9 1.8 2 0 0 2 2 2 0 Paf1 ORC_WH_C PF18137.1 RUS84899.1 - 0.71 9.9 13.4 1.8 8.6 13.4 1.6 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal PTPRCAP PF15713.5 RUS84899.1 - 0.79 10.0 24.2 1.9 8.8 24.2 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated GNAT_acetyltr_2 PF13718.6 RUS84899.1 - 0.93 8.8 4.1 1.4 8.2 4.1 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CDC45 PF02724.14 RUS84899.1 - 0.94 7.7 20.5 1.4 7.1 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 RUS84899.1 - 1.2 7.8 13.6 1.7 7.3 13.6 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 RUS84899.1 - 1.6 8.9 15.1 0.18 12.0 10.6 1.7 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TFIIF_alpha PF05793.12 RUS84899.1 - 1.6 7.2 31.2 3.6 6.1 31.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Connexin PF00029.19 RUS84899.1 - 1.6 8.4 10.7 2.9 7.6 10.7 1.3 1 0 0 1 1 1 0 Connexin Usp PF00582.26 RUS84899.1 - 1.7 9.1 8.8 4.2 7.9 8.8 1.6 1 0 0 1 1 1 0 Universal stress protein family RPN2_C PF18004.1 RUS84899.1 - 1.8 8.5 17.8 3.7 7.4 17.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 RUS84899.1 - 2 7.8 21.0 4.3 6.7 21.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4471 PF14740.6 RUS84899.1 - 2 7.6 8.7 3.6 6.7 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) RAB3GAP2_C PF14656.6 RUS84899.1 - 2.2 6.4 8.2 3.1 5.9 8.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CobT PF06213.12 RUS84899.1 - 2.4 7.5 27.3 4.5 6.6 27.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MIF4G_like_2 PF09090.11 RUS84899.1 - 2.8 7.4 10.1 4.5 6.7 10.1 1.3 1 0 0 1 1 1 0 MIF4G like V_ATPase_I PF01496.19 RUS84899.1 - 3.6 5.4 9.8 4.7 5.0 9.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 RUS84899.1 - 4.1 6.1 5.0 5.8 5.6 5.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Sporozoite_P67 PF05642.11 RUS84899.1 - 5.2 5.0 9.2 9.4 4.2 9.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XAP5 PF04921.14 RUS84899.1 - 7 6.4 15.8 15 5.3 15.8 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator PI3K_1B_p101 PF10486.9 RUS84899.1 - 7.5 4.2 17.8 11 3.7 17.3 1.5 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RS4NT PF08071.12 RUS84900.1 - 0.007 16.5 26.3 6.8 6.9 0.1 7.5 5 4 1 6 6 6 4 RS4NT (NUC023) domain SCAB-Ig PF16709.5 RUS84900.1 - 0.023 14.7 0.4 6 7.0 0.0 3.6 1 1 3 4 4 4 0 Ig domain of plant-specific actin-binding protein DUF2335 PF10097.9 RUS84900.1 - 4.1 7.4 11.1 29 4.7 0.1 5.1 3 2 3 6 6 6 0 Predicted membrane protein (DUF2335) SecE PF00584.20 RUS84900.1 - 5.5 7.0 11.2 3.8 7.5 1.3 3.1 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex TPT PF03151.16 RUS84901.1 - 3e-11 43.2 11.7 5.4e-11 42.4 11.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS84901.1 - 4.1e-08 33.5 29.3 4e-05 23.8 11.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family MFS_1 PF07690.16 RUS84902.1 - 2.8e-06 26.5 9.6 0.00011 21.3 1.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily SdpI PF13630.6 RUS84902.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.2 2 1 0 2 2 2 0 SdpI/YhfL protein family APP_E2 PF12925.7 RUS84903.1 - 1.3e-28 100.0 9.7 1.8e-28 99.5 9.7 1.2 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 RUS84903.1 - 7.9e-25 87.1 2.5 9.7e-25 86.9 0.0 2.4 3 1 0 3 3 3 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 RUS84903.1 - 9.5e-20 71.1 5.2 9.5e-20 71.1 5.2 2.0 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD Cytokin_check_N PF10407.9 RUS84903.1 - 0.014 15.3 0.1 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus DUF3813 PF12758.7 RUS84903.1 - 0.016 15.6 3.5 0.032 14.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) V_ATPase_I PF01496.19 RUS84903.1 - 0.042 11.8 0.4 0.06 11.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSCB_C PF07743.13 RUS84903.1 - 0.07 13.6 5.6 0.12 12.8 4.0 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF5343 PF17278.2 RUS84903.1 - 0.071 13.2 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5343) TipAS PF07739.13 RUS84903.1 - 0.11 13.0 10.1 0.33 11.5 6.0 2.5 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain KfrA_N PF11740.8 RUS84903.1 - 0.28 11.9 6.6 0.58 10.9 6.6 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RseA_C PF03873.13 RUS84903.1 - 2.6 8.4 4.5 30 5.0 0.1 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain APP_amyloid PF10515.9 RUS84904.1 - 5.3e-23 81.3 1.3 1.3e-22 80.0 1.3 1.6 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus Amnionless PF14828.6 RUS84904.1 - 0.0018 17.2 0.2 0.0034 16.3 0.1 1.3 1 1 0 1 1 1 1 Amnionless YL1 PF05764.13 RUS84904.1 - 0.009 16.2 0.7 0.0094 16.1 0.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein EphA2_TM PF14575.6 RUS84904.1 - 0.028 15.3 0.4 0.074 13.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RUS84904.1 - 0.066 13.5 0.2 0.23 11.8 0.0 1.8 1 1 1 2 2 2 0 Orf78 (ac78) Pes-10 PF07149.11 RUS84904.1 - 0.42 9.6 8.0 0.54 9.3 8.0 1.1 1 0 0 1 1 1 0 Pes-10 Ig_3 PF13927.6 RUS84906.1 - 7.2e-30 103.4 0.0 2.9e-11 43.8 0.0 5.4 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS84906.1 - 5.3e-27 93.7 0.0 1.3e-10 41.2 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 RUS84906.1 - 5.6e-18 64.9 1.9 3.5e-08 33.5 0.0 5.1 4 1 0 4 4 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS84906.1 - 6.7e-18 64.8 0.1 3.9e-06 27.1 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain fn3 PF00041.21 RUS84906.1 - 1.1e-13 51.3 3.1 1.6e-09 38.0 0.7 3.9 3 0 0 3 3 3 2 Fibronectin type III domain V-set PF07686.17 RUS84906.1 - 4.8e-09 36.4 4.8 0.051 13.7 0.0 5.7 5 1 0 5 5 5 3 Immunoglobulin V-set domain Tissue_fac PF01108.17 RUS84906.1 - 7e-05 22.6 2.5 0.029 14.2 0.1 3.5 2 1 1 3 3 3 1 Tissue factor Syndecan PF01034.20 RUS84906.1 - 0.001 18.9 0.9 0.003 17.5 0.9 1.7 1 0 0 1 1 1 1 Syndecan domain Ig_4 PF16680.5 RUS84906.1 - 0.013 15.7 0.0 2.6 8.4 0.0 3.7 4 0 0 4 4 3 0 T-cell surface glycoprotein CD3 delta chain DUF4998 PF16389.5 RUS84906.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function ChitinaseA_N PF08329.10 RUS84906.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Neur_chan_memb PF02932.16 RUS84906.1 - 2.7 8.0 8.9 0.42 10.6 1.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF936 PF06075.12 RUS84907.1 - 0.071 12.0 25.0 0.084 11.8 25.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Neur_chan_memb PF02932.16 RUS84907.1 - 0.1 12.6 12.8 0.13 12.3 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 RUS84907.1 - 0.11 11.2 20.4 0.13 11.0 20.4 1.1 1 0 0 1 1 1 0 Presenilin CAC1F_C PF16885.5 RUS84907.1 - 0.53 9.9 13.0 0.63 9.6 13.0 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SLC12 PF03522.15 RUS84907.1 - 0.83 8.6 19.9 0.97 8.4 19.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 RUS84907.1 - 0.99 9.4 27.3 1.4 8.9 27.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF2151 PF10221.9 RUS84907.1 - 1.5 7.3 18.9 2 6.9 18.9 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Folate_carrier PF01770.18 RUS84907.1 - 3.4 6.3 11.0 0.33 9.6 6.2 1.6 2 0 0 2 2 2 0 Reduced folate carrier Serinc PF03348.15 RUS84907.1 - 3.6 6.4 14.4 5.5 5.8 14.4 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) Scs3p PF10261.9 RUS84907.1 - 4.1 6.8 7.9 9 5.7 7.9 1.7 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PA26 PF04636.13 RUS84907.1 - 4.3 6.1 9.3 4.9 6.0 9.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Membralin PF09746.9 RUS84907.1 - 5.3 6.0 10.0 6.2 5.8 10.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 RUS84907.1 - 6 5.2 7.7 6.8 5.0 7.2 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 RUS84907.1 - 7.2 4.4 24.5 0.091 10.7 16.1 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 RUS84907.1 - 7.8 3.5 10.3 8.1 3.4 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 RUS84907.1 - 9.2 4.3 17.4 11 4.0 17.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 RUS84907.1 - 9.5 4.9 14.1 11 4.6 14.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF445 PF04286.12 RUS84909.1 - 0.047 13.5 1.0 0.049 13.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.6 RUS84909.1 - 0.19 11.8 3.7 0.65 10.0 4.0 1.7 1 1 1 2 2 2 0 YpjP-like protein SseC PF04888.12 RUS84909.1 - 0.32 10.5 6.2 1.5 8.4 6.2 2.0 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Tam41_Mmp37 PF09139.11 RUS84909.1 - 0.81 9.1 7.7 1.1 8.6 7.7 1.4 1 1 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial RHD3 PF05879.12 RUS84909.1 - 1.1 7.3 8.8 1.3 7.0 8.8 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Cornifin PF02389.15 RUS84909.1 - 1.4 9.1 28.3 5.8 7.1 28.3 1.8 1 1 0 1 1 1 0 Cornifin (SPRR) family DUF668 PF05003.12 RUS84909.1 - 5.3 7.6 9.7 5 7.7 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF668) WASH-7_mid PF14744.6 RUS84909.1 - 5.9 5.9 8.2 2.7 7.0 6.1 1.5 1 1 1 2 2 2 0 WASH complex subunit 7 HK97-gp10_like PF04883.12 RUS84909.1 - 6.5 7.8 20.3 1.8e+04 -8.0 20.3 4.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Shisa PF13908.6 RUS84910.1 - 0.004 17.4 0.2 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 RUS84910.1 - 0.0075 17.1 0.0 0.013 16.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 RUS84910.1 - 0.064 13.3 0.2 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region SdrG_C_C PF10425.9 RUS84911.1 - 0.056 13.5 0.0 0.096 12.8 0.0 1.5 1 1 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin zf-RanBP PF00641.18 RUS84911.1 - 0.48 9.8 3.9 0.29 10.5 1.1 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others UCH PF00443.29 RUS84912.1 - 7.9e-60 202.5 0.5 1.3e-59 201.8 0.5 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS84912.1 - 1.4e-08 34.7 0.6 0.0019 17.8 0.5 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Condensin2nSMC PF12422.8 RUS84912.1 - 0.0054 16.9 0.1 0.0099 16.1 0.1 1.4 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit TAS2R PF05296.13 RUS84913.1 - 0.057 12.5 0.1 0.08 12.0 0.1 1.1 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) BLM10_N PF16547.5 RUS84913.1 - 0.088 13.1 0.4 0.25 11.6 0.4 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Ribosomal_S8e PF01201.22 RUS84915.1 - 1.5e-45 154.7 13.2 1.5e-45 154.7 13.2 2.3 1 1 1 2 2 2 1 Ribosomal protein S8e Ureide_permease PF07168.11 RUS84915.1 - 2.9 6.6 5.1 4.3 6.0 5.1 1.2 1 0 0 1 1 1 0 Ureide permease Arginase PF00491.21 RUS84916.1 - 4e-71 239.8 0.1 4.8e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 RUS84916.1 - 0.048 13.9 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF1943 PF09172.11 RUS84918.1 - 8.3e-20 71.2 1.1 1.6e-19 70.3 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 RUS84918.1 - 3.5e-10 40.3 2.3 1e-09 38.8 0.0 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1081) DUF402 PF04167.13 RUS84918.1 - 0.15 12.3 1.6 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF402) Vitellogenin_N PF01347.22 RUS84919.1 - 2e-65 221.4 0.0 2.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.6 RUS84919.1 - 0.00027 21.3 0.0 0.51 10.8 0.0 3.0 2 1 1 3 3 3 3 HEAT repeats DEAD PF00270.29 RUS84921.1 - 2e-42 144.9 0.0 2e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS84921.1 - 1.9e-28 99.0 0.9 1.3e-27 96.3 0.5 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_2 PF07716.15 RUS84923.1 - 8.6e-06 25.8 24.4 0.0046 17.0 2.3 4.2 4 0 0 4 4 4 3 Basic region leucine zipper TPR_MLP1_2 PF07926.12 RUS84923.1 - 7.5e-05 22.8 30.0 0.033 14.3 1.8 4.2 2 1 1 3 3 3 3 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 RUS84923.1 - 0.0054 16.8 23.7 0.028 14.5 1.1 4.2 4 0 0 4 4 4 2 bZIP transcription factor Atg14 PF10186.9 RUS84923.1 - 0.013 14.7 4.6 0.013 14.7 4.6 2.5 1 1 1 2 2 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 RUS84923.1 - 0.014 15.8 7.8 0.014 15.8 7.8 3.0 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 RUS84923.1 - 0.018 14.8 1.0 0.018 14.8 1.0 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Rootletin PF15035.6 RUS84923.1 - 0.019 15.0 25.1 0.018 15.1 22.9 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cep57_MT_bd PF06657.13 RUS84923.1 - 0.033 14.6 2.5 0.033 14.6 2.5 3.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TolA_bind_tri PF16331.5 RUS84923.1 - 0.04 14.0 1.2 0.04 14.0 1.2 3.4 4 0 0 4 4 4 0 TolA binding protein trimerisation WD40_alt PF14077.6 RUS84923.1 - 0.065 13.1 1.2 0.065 13.1 1.2 3.3 3 1 0 3 3 3 0 Alternative WD40 repeat motif ZapB PF06005.12 RUS84923.1 - 0.24 11.9 28.2 0.52 10.8 10.6 3.3 2 2 0 2 2 2 0 Cell division protein ZapB FapA PF03961.13 RUS84923.1 - 0.36 9.4 14.2 0.44 9.1 1.4 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 RUS84923.1 - 0.77 9.1 20.4 0.43 9.9 9.5 2.3 1 1 1 2 2 2 0 FAM76 protein YabA PF06156.13 RUS84923.1 - 0.88 10.2 16.5 1.1 10.0 2.7 3.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 RUS84923.1 - 1.1 8.6 14.2 4.9 6.4 5.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Shugoshin_N PF07558.11 RUS84923.1 - 1.5 8.8 12.4 0.7 9.8 2.2 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.9 RUS84923.1 - 2.1 8.4 18.2 1.9 8.5 0.2 3.6 4 0 0 4 4 4 0 Short coiled-coil protein LD_cluster2 PF18163.1 RUS84923.1 - 2.8 7.4 6.5 5.7 6.4 0.1 2.5 2 1 1 3 3 3 0 SLOG cluster2 Paralemmin PF03285.15 RUS84923.1 - 4.4 6.8 16.4 0.45 10.1 4.0 2.1 1 1 1 2 2 2 0 Paralemmin SlyX PF04102.12 RUS84923.1 - 5.6 7.7 13.7 4.8 7.9 0.1 4.1 3 1 1 4 4 4 0 SlyX TSC22 PF01166.18 RUS84923.1 - 5.8 7.3 16.7 0.84 10.0 1.2 3.5 4 0 0 4 4 4 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 RUS84923.1 - 7.4 6.6 31.5 1.6 8.7 3.8 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 RUS84923.1 - 7.6 6.4 23.1 0.5 10.2 1.2 4.1 4 0 0 4 4 4 0 Septum formation initiator MCC-bdg_PDZ PF10506.9 RUS84923.1 - 9.3 6.4 10.5 6 7.0 1.3 3.5 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome MerR-DNA-bind PF09278.11 RUS84923.1 - 9.4 6.9 17.2 6 7.5 0.2 3.8 3 1 1 4 4 4 0 MerR, DNA binding COMPASS-Shg1 PF05205.12 RUS84924.1 - 0.1 13.3 0.6 0.3 11.8 0.6 1.9 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3287 PF11690.8 RUS84925.1 - 2.3e-05 24.1 3.2 2.3e-05 24.1 3.2 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF3287) BAF1_ABF1 PF04684.13 RUS84925.1 - 6.7 5.6 23.4 1.8 7.6 18.0 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDC27 PF09507.10 RUS84926.1 - 0.17 11.2 27.0 0.23 10.8 27.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF5401 PF17380.2 RUS84926.1 - 5.3 5.0 35.6 0.13 10.3 25.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5401) RRM_1 PF00076.22 RUS84927.1 - 8.5e-18 63.9 0.0 1.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS84927.1 - 6.2e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS84927.1 - 0.0058 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Urocanase_N PF17391.2 RUS84928.1 - 0.0084 15.8 0.7 36 4.0 0.0 3.5 1 1 1 3 3 3 3 Urocanase N-terminal domain MFS_1 PF07690.16 RUS84929.1 - 2.6e-11 43.1 4.2 3.7e-11 42.5 4.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS84929.1 - 7.1e-10 38.3 2.3 8.6e-10 38.0 2.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 RUS84929.1 - 0.00022 19.8 2.1 0.00028 19.5 2.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 RUS84929.1 - 0.0048 16.2 3.6 0.0069 15.7 3.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 RUS84930.1 - 1.1e-12 47.6 7.4 1.4e-12 47.3 7.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS84930.1 - 1e-10 41.1 8.6 1.2e-10 40.9 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3099 PF11298.8 RUS84930.1 - 0.11 12.7 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) ACOX PF01756.19 RUS84931.1 - 9.2e-56 188.2 0.0 1.4e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 RUS84931.1 - 1.4e-14 54.0 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RUS84931.1 - 1.6e-07 31.6 0.0 8e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MNR PF15718.5 RUS84932.1 - 1.9e-43 148.8 26.1 9.4e-30 103.5 19.8 3.2 2 2 0 2 2 2 2 Protein moonraker CCDC74_C PF14917.6 RUS84933.1 - 5.7e-38 130.2 1.9 5.7e-38 130.2 1.9 3.0 2 1 1 3 3 3 1 Coiled coil protein 74, C terminal CCDC92 PF14916.6 RUS84933.1 - 1.4e-19 69.5 6.0 1.4e-19 69.5 6.0 3.1 3 1 0 3 3 3 1 Coiled-coil domain of unknown function DUF4485 PF14846.6 RUS84933.1 - 0.025 14.6 0.4 0.096 12.7 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) WD40_alt PF14077.6 RUS84933.1 - 0.14 12.0 5.5 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif Hid1 PF12722.7 RUS84933.1 - 0.4 8.8 9.5 0.48 8.5 9.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TolA_bind_tri PF16331.5 RUS84933.1 - 5 7.3 24.5 2.8 8.1 5.4 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Methyltransf_16 PF10294.9 RUS84934.1 - 6.2e-38 130.2 0.2 7.8e-38 129.9 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RUS84934.1 - 8.3e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS84934.1 - 0.0021 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 RUS84934.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RUS84934.1 - 0.027 15.2 0.0 0.049 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 RUS84934.1 - 0.034 14.9 0.0 0.061 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pox_A51 PF04948.13 RUS84934.1 - 0.045 12.6 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein SAM_MT PF04445.13 RUS84934.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TRAM_LAG1_CLN8 PF03798.16 RUS84936.1 - 1.7e-29 103.0 22.9 1.9e-29 102.9 22.9 1.0 1 0 0 1 1 1 1 TLC domain DUF1325 PF07039.11 RUS84937.1 - 2.9e-36 124.5 0.3 6.6e-36 123.3 0.0 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain SIMPL PF04402.14 RUS84937.1 - 0.0038 17.7 0.2 0.0052 17.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF541) ISG65-75 PF11727.8 RUS84937.1 - 0.0068 15.7 5.8 0.011 14.9 5.8 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein Syntaxin PF00804.25 RUS84937.1 - 0.012 15.3 6.0 0.018 14.7 6.0 1.2 1 0 0 1 1 1 0 Syntaxin BTB_2 PF02214.22 RUS84939.1 - 6.6e-11 42.4 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 RUS84940.1 - 2.8e-29 102.1 13.1 3.5e-29 101.8 13.1 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS84940.1 - 9.7e-13 47.9 5.3 9.7e-13 47.9 5.3 2.1 2 0 0 2 2 2 1 Ion channel DHHC PF01529.20 RUS84940.1 - 9.7 6.3 7.5 7.1 6.8 0.6 2.3 1 1 2 3 3 3 0 DHHC palmitoyltransferase DUF1647 PF07801.11 RUS84942.1 - 3.3e-08 33.4 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1647) DUF3248 PF11609.8 RUS84942.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Q_salvage PF10343.9 RUS84942.1 - 0.11 12.0 0.1 9.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Filamin PF00630.19 RUS84943.1 - 0.011 16.6 0.0 0.02 15.7 0.0 1.3 1 0 0 1 1 1 0 Filamin/ABP280 repeat Lipase_GDSL_2 PF13472.6 RUS84943.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF913 PF06025.12 RUS84944.1 - 0.15 11.0 16.0 1 8.2 16.0 2.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 RUS84944.1 - 3 7.8 62.7 0.011 15.7 51.1 3.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Acid_PPase PF12689.7 RUS84945.1 - 2.5e-54 183.7 0.0 3.2e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 RUS84945.1 - 2e-06 28.0 0.0 6.8e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 RUS84945.1 - 0.0043 16.8 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 RUS84945.1 - 0.079 12.4 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) TTL PF03133.15 RUS84946.1 - 6.4e-92 307.8 0.5 8.7e-92 307.4 0.5 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS84946.1 - 2.4e-07 30.3 0.3 0.0043 16.3 0.0 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS84946.1 - 0.00015 21.1 0.0 0.0015 17.8 0.0 2.3 1 1 0 1 1 1 1 Sugar-transfer associated ATP-grasp HTH_54 PF18607.1 RUS84946.1 - 0.047 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 ParA helix turn helix domain Cytochrom_C1 PF02167.15 RUS84947.1 - 1.1e-93 313.0 0.0 1.3e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RUS84947.1 - 0.00048 20.4 0.1 0.00097 19.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RUS84947.1 - 0.0053 17.9 0.5 0.012 16.8 0.5 1.7 1 1 0 1 1 1 1 Cytochrome c Glyco_transf_90 PF05686.12 RUS84948.1 - 7.7e-99 331.3 0.2 1e-98 330.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 RUS84948.1 - 5.9e-09 36.7 0.0 1.1e-08 35.8 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Defensin_4 PF07936.12 RUS84948.1 - 0.11 12.4 1.3 0.33 10.9 1.3 1.8 1 0 0 1 1 1 0 Potassium-channel blocking toxin BEN PF10523.9 RUS84949.1 - 1e-07 32.0 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 BEN domain CDC73_N PF16050.5 RUS84950.1 - 2.1e-124 414.7 1.7 2.1e-124 414.7 1.7 1.3 2 0 0 2 2 2 1 Paf1 complex subunit CDC73 N-terminal zf-C3HC4_3 PF13920.6 RUS84951.1 - 2.7e-12 46.3 9.0 3.6e-12 45.9 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS84951.1 - 5.6e-08 32.5 7.5 8.1e-08 32.0 7.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS84951.1 - 8.8e-08 32.4 9.8 1.3e-07 31.9 9.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS84951.1 - 4.3e-06 26.5 11.2 6.9e-06 25.8 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS84951.1 - 0.00015 21.5 9.8 0.00026 20.8 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 RUS84951.1 - 0.0037 17.0 6.6 0.0081 15.9 6.6 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 RUS84951.1 - 0.0072 16.3 8.8 0.013 15.4 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS84951.1 - 0.053 13.6 5.7 0.13 12.3 5.7 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_5 PF17121.5 RUS84951.1 - 0.13 12.1 7.1 0.35 10.8 7.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Insulin_TMD PF17870.1 RUS84951.1 - 0.18 11.9 0.1 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DHHC PF01529.20 RUS84952.1 - 1.4e-23 83.5 15.1 1.4e-23 83.5 15.1 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Synaptobrevin PF00957.21 RUS84953.1 - 6.3e-23 80.4 1.2 6.7e-23 80.3 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 RUS84953.1 - 0.077 12.5 0.1 0.087 12.4 0.1 1.1 1 0 0 1 1 1 0 fzo-like conserved region Beta_helix PF13229.6 RUS84954.1 - 3.9e-43 147.0 32.0 3.5e-28 98.4 16.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 RUS84954.1 - 6.9e-21 74.6 16.4 3.1e-13 49.6 10.0 2.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 RUS84954.1 - 1.4e-13 50.5 0.0 3.6e-13 49.2 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS84954.1 - 8.8e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RUS84954.1 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 F-box EF-hand_7 PF13499.6 RUS84955.1 - 7.4e-11 42.3 7.1 1.9e-08 34.6 1.8 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS84955.1 - 1.3e-09 37.8 3.9 9.5e-06 25.4 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS84955.1 - 5.3e-09 35.3 9.1 0.00037 20.2 0.9 4.9 4 2 1 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 RUS84955.1 - 4.7e-08 32.0 6.6 9.3e-06 24.8 1.7 4.7 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.6 RUS84955.1 - 0.00055 19.3 0.6 0.00055 19.3 0.6 3.5 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 RUS84955.1 - 0.0065 16.8 0.2 0.015 15.6 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain Excalibur PF05901.11 RUS84955.1 - 0.12 13.0 0.7 2.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Excalibur calcium-binding domain US6 PF17616.2 RUS84956.1 - 0.016 15.2 0.2 0.047 13.7 0.2 1.7 1 0 0 1 1 1 0 Viral unique short region 6 DUF2796 PF10986.8 RUS84957.1 - 0.03 14.3 5.6 0.04 13.9 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Med8 PF10232.9 RUS84957.1 - 0.82 9.2 13.1 0.87 9.1 1.4 2.1 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 MCM_bind PF09739.9 RUS84957.1 - 6.6 5.1 10.4 7.4 4.9 10.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Homeodomain PF00046.29 RUS84958.1 - 2.7e-22 78.3 4.8 4.8e-22 77.6 4.8 1.4 1 0 0 1 1 1 1 Homeodomain NAD_binding_1 PF00175.21 RUS84958.1 - 0.00093 19.8 0.0 0.0026 18.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Homeobox_KN PF05920.11 RUS84958.1 - 0.0069 16.3 0.2 0.0069 16.3 0.2 2.7 3 0 0 3 3 3 1 Homeobox KN domain GlgS PF08971.11 RUS84958.1 - 0.057 13.5 0.2 0.15 12.1 0.2 1.8 1 0 0 1 1 1 0 Glycogen synthesis protein AIG1 PF04548.16 RUS84958.1 - 0.25 10.7 0.1 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 AIG1 family EF-hand_6 PF13405.6 RUS84959.1 - 3.6e-08 32.7 1.4 0.00017 21.3 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS84959.1 - 9.4e-08 32.4 2.6 1.4e-07 31.8 2.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS84959.1 - 4.4e-06 25.9 1.6 0.0062 16.0 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS84959.1 - 0.00018 21.3 0.2 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS84959.1 - 0.079 12.5 1.0 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 EF hand OATP PF03137.20 RUS84959.1 - 0.16 10.2 0.4 0.23 9.7 0.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Draxin PF15550.6 RUS84959.1 - 1.8 8.3 12.6 2.7 7.8 12.5 1.4 1 1 0 1 1 1 0 Draxin Methyltransf_11 PF08241.12 RUS84960.1 - 4.2e-12 46.6 0.0 7.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS84960.1 - 2.2e-11 44.3 0.0 3.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS84960.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 RUS84960.1 - 2e-06 27.7 0.0 2.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS84960.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS84960.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 RUS84960.1 - 0.032 15.0 0.0 0.05 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 RUS84960.1 - 0.12 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fibrinogen_C PF00147.18 RUS84961.1 - 1e-54 185.7 7.0 1.6e-54 185.1 7.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain NPV_P10 PF05531.12 RUS84961.1 - 0.007 16.8 1.5 0.16 12.5 0.2 2.6 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 RUS84961.1 - 0.0077 15.8 4.2 0.19 11.2 0.1 2.2 1 1 1 2 2 2 2 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 RUS84961.1 - 0.033 14.2 6.7 0.5 10.4 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LcrG PF07216.12 RUS84961.1 - 0.1 12.5 0.3 0.29 11.1 0.3 1.7 1 0 0 1 1 1 0 LcrG protein DUF5104 PF17117.5 RUS84961.1 - 0.11 12.9 0.6 0.39 11.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) Antimicrobial12 PF08107.11 RUS84961.1 - 0.16 11.7 1.1 0.31 10.8 1.1 1.4 1 0 0 1 1 1 0 Pleurocidin family THOC7 PF05615.13 RUS84961.1 - 0.19 12.0 2.4 0.39 11.0 1.1 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Apolipoprotein PF01442.18 RUS84961.1 - 0.25 11.2 5.9 5.3 6.9 0.7 1.9 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 RUS84961.1 - 0.62 8.9 6.1 0.9 8.4 6.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YojJ PF10372.9 RUS84961.1 - 0.73 10.0 3.9 7.4 6.7 0.1 2.7 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 RUS84961.1 - 1.3 9.1 5.5 6 6.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C2H2 PF00096.26 RUS84962.1 - 2.8e-14 52.7 41.1 0.00033 21.0 1.6 7.0 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS84962.1 - 7.2e-13 48.2 45.7 0.0039 17.9 0.1 7.4 7 0 0 7 7 6 5 C2H2-type zinc finger zf-met PF12874.7 RUS84962.1 - 7.2e-12 45.3 18.1 0.1 13.0 0.1 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS84962.1 - 5.6e-10 39.0 31.9 8.6e-05 22.4 2.0 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS84962.1 - 7.4e-10 38.9 26.1 0.00084 19.6 0.1 7.2 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding ELM2 PF01448.24 RUS84962.1 - 1.6e-07 32.0 0.1 5.6e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 ELM2 domain zf-Di19 PF05605.12 RUS84962.1 - 0.00058 20.1 1.4 0.00058 20.1 1.4 4.0 4 0 0 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS84962.1 - 0.0053 17.1 0.7 0.0053 17.1 0.7 8.5 9 0 0 9 9 9 3 Zinc-finger double domain Myb_DNA-binding PF00249.31 RUS84962.1 - 0.013 15.7 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2HC_2 PF13913.6 RUS84962.1 - 0.032 14.1 0.2 0.032 14.1 0.2 2.8 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Ribosomal_60s PF00428.19 RUS84962.1 - 0.72 10.5 19.0 0.88 10.2 10.7 3.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_9 PF16293.5 RUS84962.1 - 1.5 8.7 5.5 0.91 9.4 0.0 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 RUS84962.1 - 3.2 7.9 7.9 0.5 10.5 0.1 3.2 3 1 1 4 4 3 0 KIAA1045 RING finger GBP PF02263.19 RUS84963.1 - 2.9e-93 311.9 0.0 4.9e-93 311.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 RUS84963.1 - 0.00017 21.1 0.7 0.00029 20.4 0.7 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 RUS84963.1 - 0.0029 18.0 0.5 0.0074 16.7 0.1 1.9 2 0 0 2 2 2 1 T-lymphoma invasion and metastasis CC-Ex domain GFRP PF06399.13 RUS84964.1 - 1.5e-35 120.9 0.0 2.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) HPD PF05044.12 RUS84965.1 - 5.8e-77 256.9 5.3 6.5e-77 256.7 5.3 1.0 1 0 0 1 1 1 1 Homeo-prospero domain NifW PF03206.14 RUS84967.1 - 0.023 15.2 0.9 0.079 13.5 0.9 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein NifW 2-oxoacid_dh PF00198.23 RUS84968.1 - 4.6e-79 265.1 0.4 6.6e-79 264.6 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RUS84968.1 - 1.8e-18 66.2 0.2 3.3e-18 65.3 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 RUS84968.1 - 0.01 15.0 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 RUS84968.1 - 0.014 15.3 0.1 0.038 13.9 0.1 1.6 1 1 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 RUS84968.1 - 0.12 12.3 0.1 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like LRR_6 PF13516.6 RUS84970.1 - 9.6e-26 87.6 20.5 0.0027 17.6 0.0 8.8 9 0 0 9 9 9 8 Leucine Rich repeat LRR_1 PF00560.33 RUS84970.1 - 1.8e-10 39.9 5.8 9.8 7.2 0.0 8.1 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_4 PF12799.7 RUS84970.1 - 4.2e-07 30.2 11.1 0.039 14.4 0.3 5.8 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS84970.1 - 0.00022 20.9 15.3 0.00073 19.3 2.5 4.9 3 2 0 3 3 3 2 Leucine rich repeat EF-hand_6 PF13405.6 RUS84970.1 - 0.11 12.4 0.1 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain RSN1_7TM PF02714.15 RUS84971.1 - 1.8e-46 158.7 21.9 1.8e-46 158.7 21.9 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RUS84971.1 - 8.4e-33 114.1 0.1 1.1e-32 113.7 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 RUS84972.1 - 3e-16 59.6 0.9 3.6e-14 52.8 0.1 2.2 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport Orf78 PF06024.12 RUS84972.1 - 0.11 12.8 0.8 0.79 10.0 0.1 2.1 2 0 0 2 2 2 0 Orf78 (ac78) YrhC PF14143.6 RUS84972.1 - 0.8 9.8 4.4 0.33 11.1 1.2 2.0 2 0 0 2 2 2 0 YrhC-like protein Lig_chan-Glu_bd PF10613.9 RUS84973.1 - 6.4e-23 81.1 0.0 8.2e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS84973.1 - 8.9e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 RUS84974.1 - 2.9e-14 53.2 0.0 4.8e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS84974.1 - 2e-07 30.7 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2608 PF11019.8 RUS84974.1 - 0.083 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) zf-met PF12874.7 RUS84975.1 - 0.0016 18.8 9.8 0.13 12.7 6.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS84975.1 - 0.062 13.6 6.4 0.61 10.5 2.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CCHC PF00098.23 RUS84976.1 - 6.3e-06 26.0 3.4 1e-05 25.4 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS84976.1 - 0.00033 20.4 3.3 0.00056 19.7 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS84976.1 - 0.0043 17.0 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS84976.1 - 0.07 12.9 2.7 0.13 12.0 2.7 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Carla_C4 PF01623.17 RUS84976.1 - 2.1 8.4 7.0 5.1 7.1 7.0 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Prp18 PF02840.15 RUS84977.1 - 4.2e-60 201.9 1.5 4.8e-60 201.8 0.1 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 RUS84977.1 - 1.2e-12 47.1 0.9 1.2e-12 47.1 0.9 2.4 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.6 RUS84977.1 - 0.053 14.0 0.2 34 5.0 0.0 3.7 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain ATG101 PF07855.12 RUS84977.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 101 Ldl_recept_a PF00057.18 RUS84978.1 - 1.3e-22 79.7 54.6 1.5e-09 37.9 15.0 3.7 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 RUS84978.1 - 3.7e-20 72.1 9.6 9.1e-05 22.9 0.0 8.7 8 1 0 8 8 8 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 RUS84978.1 - 1.2e-10 41.5 7.0 1.2e-10 41.5 7.0 3.9 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site SGL PF08450.12 RUS84978.1 - 2.9e-05 23.8 0.0 0.0018 17.9 0.0 3.1 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RUS84978.1 - 0.047 13.7 0.4 17 5.7 0.0 5.0 6 0 0 6 6 6 0 NHL repeat cEGF PF12662.7 RUS84978.1 - 0.1 12.6 12.9 0.11 12.4 0.3 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like PH_14 PF17787.1 RUS84978.1 - 0.18 11.7 0.0 5.9 6.8 0.0 2.7 3 0 0 3 3 3 0 PH domain EGF_2 PF07974.13 RUS84980.1 - 0.037 14.4 8.1 0.095 13.1 8.1 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 RUS84980.1 - 0.049 13.8 4.5 0.11 12.7 4.5 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain DAG1 PF05454.11 RUS84980.1 - 0.089 12.2 0.3 0.32 10.3 0.0 2.0 3 0 0 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) hEGF PF12661.7 RUS84980.1 - 0.23 12.2 3.7 0.8 10.4 3.7 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF Trans_coact PF16805.5 RUS84981.1 - 0.24 11.5 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Phage late-transcription coactivator EGF_2 PF07974.13 RUS84982.1 - 0.00016 22.0 24.5 0.00077 19.8 9.8 4.3 4 0 0 4 4 4 3 EGF-like domain EGF PF00008.27 RUS84982.1 - 0.014 15.7 3.4 0.014 15.7 3.4 4.1 4 1 0 4 4 4 0 EGF-like domain Thyroglobulin_1 PF00086.18 RUS84983.1 - 3.7e-13 48.9 32.5 2e-05 24.1 0.0 7.7 7 0 0 7 7 7 5 Thyroglobulin type-1 repeat EGF PF00008.27 RUS84983.1 - 3.9e-10 39.8 47.6 6e-06 26.5 8.1 17.4 19 1 0 19 19 19 9 EGF-like domain SEA PF01390.20 RUS84983.1 - 4.7e-06 26.6 0.1 0.19 11.9 0.0 2.7 3 0 0 3 3 3 2 SEA domain WAP PF00095.21 RUS84983.1 - 5.5e-05 23.5 31.7 0.00067 20.0 12.9 10.6 12 1 0 12 12 12 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' Antistasin PF02822.14 RUS84983.1 - 0.0012 19.4 9.3 0.0012 19.4 9.3 9.6 11 1 0 11 11 11 1 Antistasin family DNAP_B_exo_N PF08452.10 RUS84984.1 - 1.5e-07 30.7 15.7 13 5.4 0.0 10.4 12 0 0 12 12 12 6 DNA polymerase family B exonuclease domain, N-terminal Thyroglobulin_1 PF00086.18 RUS84985.1 - 3.6e-20 71.4 4.6 4.6e-09 35.8 0.1 3.0 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat WAP PF00095.21 RUS84985.1 - 1.7e-17 63.5 82.9 1.9e-08 34.5 14.8 7.3 8 0 0 8 8 8 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Kunitz_BPTI PF00014.23 RUS84985.1 - 6.1e-12 45.6 5.4 6.1e-12 45.6 5.4 3.0 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Lustrin_cystein PF14625.6 RUS84985.1 - 1.1e-05 25.6 8.0 1.1e-05 25.6 8.0 5.9 5 2 1 6 6 6 1 Lustrin, cysteine-rich repeated domain HXXSHH PF07586.11 RUS84985.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Kunitz_BPTI PF00014.23 RUS84986.1 - 3.2e-28 97.7 31.6 6.9e-17 61.4 4.9 4.2 3 1 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Thyroglobulin_1 PF00086.18 RUS84986.1 - 1.1e-11 44.2 6.6 1.1e-11 44.2 6.6 2.2 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat WAP PF00095.21 RUS84986.1 - 1.2e-09 38.4 17.6 1.2e-09 38.4 17.6 6.2 5 2 1 6 6 6 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF3295 PF11702.8 RUS84986.1 - 0.25 10.6 3.8 0.38 10.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PBP1_TM PF14812.6 RUS84986.1 - 1.4 9.3 7.7 2.5 8.5 7.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3697 PF12478.8 RUS84987.1 - 1.1e-10 41.4 0.1 2.8e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 DUF1296 PF06972.11 RUS84987.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) FA_desaturase_2 PF03405.14 RUS84987.1 - 8.8 5.1 8.0 4.1 6.2 3.5 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Dus PF01207.17 RUS84988.1 - 1.1e-59 202.0 0.0 2.2e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 RUS84988.1 - 9.9e-06 25.3 13.4 0.00051 19.9 1.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RUS84988.1 - 0.0003 20.5 2.0 0.0003 20.5 2.0 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RUS84988.1 - 0.087 12.9 12.0 0.13 12.3 1.2 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 RUS84988.1 - 4.4 7.9 5.8 5.1 7.7 1.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TPR_8 PF13181.6 RUS84990.1 - 1.1e-06 28.4 5.4 0.006 16.7 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS84990.1 - 1.2e-06 28.2 6.9 0.42 10.9 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS84990.1 - 3.4e-05 23.5 9.2 0.9 9.5 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS84990.1 - 5.1e-05 23.4 0.8 0.0096 16.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS84990.1 - 0.001 18.7 0.3 0.13 11.9 0.0 3.8 4 0 0 4 4 4 1 TPR repeat TTC5_OB PF16669.5 RUS84991.1 - 1.3e-31 108.6 0.2 2.6e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_1 PF00515.28 RUS84991.1 - 3.8e-10 39.2 7.3 0.00047 19.9 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS84991.1 - 1.2e-09 37.7 0.8 0.0014 18.3 0.0 4.8 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.17 RUS84991.1 - 2.5e-08 33.4 9.9 0.015 15.4 0.0 4.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS84991.1 - 2.3e-06 28.1 0.6 0.00016 22.3 0.0 3.1 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS84991.1 - 3.9e-06 26.9 0.9 0.26 11.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS84991.1 - 3.8e-05 24.1 2.3 0.042 14.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS84991.1 - 7.9e-05 22.6 8.8 0.0095 16.1 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS84991.1 - 0.0081 16.4 2.0 5.3 7.4 0.0 4.0 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS84991.1 - 0.064 13.4 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TOM20_plant PF06552.12 RUS84991.1 - 0.11 12.2 0.1 0.35 10.6 0.0 1.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 RUS84991.1 - 0.13 12.3 0.0 10 6.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS84991.1 - 0.39 11.7 2.7 3.9 8.5 0.0 3.7 2 2 3 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 RUS84992.1 - 1.8e-41 139.3 24.9 4.2e-10 40.1 0.2 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS84992.1 - 4.2e-07 30.2 3.1 0.78 10.1 0.0 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS84992.1 - 8.6e-06 25.3 3.4 0.00072 19.0 0.2 3.1 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 RUS84992.1 - 5.2e-05 22.1 5.6 0.51 8.9 0.1 3.4 2 1 0 3 3 3 3 Nucleoporin Nup120/160 zf_UBZ PF18439.1 RUS84992.1 - 0.24 11.0 1.6 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-dskA_traR PF01258.17 RUS84992.1 - 0.51 10.3 2.0 0.58 10.1 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Pectate_lyase_3 PF12708.7 RUS84995.1 - 0.0033 17.3 1.3 0.1 12.4 0.1 2.2 1 1 1 2 2 2 2 Pectate lyase superfamily protein UPA PF17217.3 RUS84995.1 - 10 6.0 12.8 1.2 9.0 5.3 2.9 1 1 2 3 3 3 0 UPA domain Tubulin PF00091.25 RUS84996.1 - 2.2e-69 233.6 0.0 3.5e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS84996.1 - 1.4e-43 148.1 0.1 2.1e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS84996.1 - 9e-06 26.0 0.1 2.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS84996.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RUS84996.1 - 0.066 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin like PAC4 PF16093.5 RUS84997.1 - 5.4e-20 71.4 0.1 6.8e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 CagX PF03524.15 RUS84998.1 - 0.029 14.1 2.0 0.05 13.3 2.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TFIIA PF03153.13 RUS84998.1 - 0.97 9.4 16.7 0.068 13.2 8.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hepsin-SRCR PF09272.10 RUS84999.1 - 0.004 17.7 0.1 0.0048 17.4 0.1 1.1 1 0 0 1 1 1 1 Hepsin, SRCR domain NAGPA PF09992.9 RUS85000.1 - 7.1e-31 107.7 0.2 7.9e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Phosphodiester glycosidase ASFV_J13L PF05568.11 RUS85001.1 - 1.1e-11 44.9 0.2 0.11 12.2 0.0 5.1 2 1 2 4 4 4 4 African swine fever virus J13L protein GIT_SHD PF08518.11 RUS85001.1 - 1.3e-06 28.0 3.0 2.1e+02 1.6 0.0 9.0 10 0 0 10 10 10 0 Spa2 homology domain (SHD) of GIT EPO_TPO PF00758.18 RUS85001.1 - 0.039 14.0 0.0 1e+02 2.9 0.0 4.3 3 1 3 6 6 6 0 Erythropoietin/thrombopoietin EF-hand_13 PF17958.1 RUS85001.1 - 0.45 10.3 3.3 2 8.3 0.4 3.2 2 1 1 3 3 3 0 EF-hand domain MBDa PF16564.5 RUS85001.1 - 0.82 9.9 6.1 1.1e+02 3.1 0.1 5.4 2 2 2 6 6 6 0 p55-binding region of Methyl-CpG-binding domain proteins MBD NAGPA PF09992.9 RUS85002.1 - 1.6e-38 132.6 0.8 2.1e-38 132.2 0.8 1.1 1 0 0 1 1 1 1 Phosphodiester glycosidase EGF_2 PF07974.13 RUS85002.1 - 0.015 15.7 14.0 0.015 15.7 14.0 2.4 3 0 0 3 3 3 0 EGF-like domain Pico_P1A PF02226.16 RUS85003.1 - 0.001 19.0 0.3 30 4.8 0.0 3.4 1 1 4 5 5 5 5 Picornavirus coat protein (VP4) DUF3760 PF12586.8 RUS85003.1 - 0.043 14.0 14.2 2.2e+02 2.1 0.0 7.4 8 0 0 8 8 8 0 Protein of unknown function (DUF3760) CoA_binding_3 PF13727.6 RUS85004.1 - 0.0094 16.0 0.2 0.014 15.4 0.2 1.2 1 0 0 1 1 1 1 CoA-binding domain 7tm_1 PF00001.21 RUS85008.1 - 2.2e-16 60.0 13.9 3.2e-16 59.5 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS85008.1 - 1.7e-13 50.6 11.1 2.3e-13 50.1 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS85008.1 - 3e-08 33.8 7.0 4.2e-08 33.3 7.0 1.3 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS85008.1 - 7.6e-08 32.3 19.9 1.5e-07 31.3 13.3 3.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS85008.1 - 0.00015 21.2 16.9 0.0083 15.5 3.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx PsaF PF17550.2 RUS85008.1 - 0.042 13.4 2.9 0.046 13.2 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function ApoB100_C PF12491.8 RUS85009.1 - 4.5e-05 23.3 0.1 67 3.6 0.0 5.5 1 1 7 8 8 8 0 Apolipoprotein B100 C terminal Sec34 PF04136.15 RUS85009.1 - 0.15 11.9 26.3 6.1 6.7 5.7 3.4 1 1 2 3 3 3 0 Sec34-like family Spc24 PF08286.11 RUS85009.1 - 1.1 9.5 19.1 1.8e+04 -7.1 19.1 3.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 H-kinase_dim PF02895.14 RUS85009.1 - 1.2 9.6 4.4 3.8e+02 1.6 4.4 3.9 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain HxlR PF01638.17 RUS85010.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Forkhead PF00250.18 RUS85011.1 - 5.6e-37 125.9 0.1 1.1e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Forkhead_N PF08430.12 RUS85011.1 - 1e-13 52.0 49.3 1e-13 52.0 49.3 3.7 2 1 0 3 3 3 1 Forkhead N-terminal region HNF_C PF09354.10 RUS85011.1 - 1.7e-05 25.7 2.7 1.7e-05 25.7 2.7 6.1 4 2 0 4 4 4 1 HNF3 C-terminal domain TFIIA PF03153.13 RUS85011.1 - 0.54 10.2 29.0 0.95 9.4 29.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 RUS85012.1 - 0.0026 18.1 21.4 0.0051 17.2 21.4 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain SDA1 PF05285.12 RUS85012.1 - 0.049 13.1 5.0 0.061 12.7 5.0 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 RUS85012.1 - 0.059 13.4 5.0 0.09 12.8 5.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 RUS85012.1 - 0.069 13.0 5.3 0.084 12.7 5.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RUS85012.1 - 0.16 10.1 18.4 0.2 9.7 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 RUS85012.1 - 0.27 10.9 3.1 0.51 10.0 3.1 1.4 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 RUS85012.1 - 0.31 10.6 6.5 0.38 10.3 6.5 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 RUS85012.1 - 1.1 9.0 21.3 1.7 8.3 21.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Chitin_bind_1 PF00187.19 RUS85013.1 - 0.51 10.8 2.8 1.2 9.7 2.8 1.6 1 0 0 1 1 1 0 Chitin recognition protein Homeodomain PF00046.29 RUS85015.1 - 1.9e-08 34.0 0.2 4.3e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain NOA36 PF06524.12 RUS85015.1 - 0.62 9.3 4.6 0.93 8.7 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RUS85015.1 - 4.7 7.7 13.1 8.3 6.9 13.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Neurensin PF14927.6 RUS85016.1 - 8.5e-31 106.4 0.0 1.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Neurensin FtsX PF02687.21 RUS85016.1 - 0.019 15.4 2.6 0.028 14.9 2.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family SDF PF00375.18 RUS85016.1 - 0.064 12.3 0.1 0.12 11.3 0.1 1.5 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family DUF2781 PF10914.8 RUS85016.1 - 0.081 13.3 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3040 PF11239.8 RUS85016.1 - 0.11 12.7 2.0 4.2 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) TMEM238 PF15125.6 RUS85016.1 - 3.8 7.8 8.4 0.22 11.7 2.0 1.9 2 0 0 2 2 2 0 TMEM238 protein family TIR PF01582.20 RUS85017.1 - 5.3e-14 52.4 0.4 1.7e-13 50.8 0.4 1.8 1 1 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS85017.1 - 3.1e-13 50.3 0.0 6.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain EGF PF00008.27 RUS85017.1 - 5.6 7.4 48.3 0.85 10.0 7.2 4.6 4 0 0 4 4 4 0 EGF-like domain DUF3246 PF11596.8 RUS85018.1 - 0.03 13.8 0.3 0.031 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cytochrom_B561 PF03188.16 RUS85019.1 - 0.00034 20.8 0.4 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2955 PF11168.8 RUS85019.1 - 0.012 15.4 2.9 0.026 14.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) SecE PF00584.20 RUS85019.1 - 0.069 13.1 0.3 0.95 9.4 0.0 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex YrhK PF14145.6 RUS85019.1 - 0.1 12.5 4.2 0.38 10.6 0.0 3.2 2 1 0 2 2 2 0 YrhK-like protein PalH PF08733.10 RUS85019.1 - 0.27 10.2 2.1 1.5 7.7 0.1 2.1 1 1 0 2 2 2 0 PalH/RIM21 Metallophos PF00149.28 RUS85020.1 - 5.6e-17 62.9 0.7 7.2e-17 62.6 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Porin_3 PF01459.22 RUS85020.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic porin Ank_2 PF12796.7 RUS85021.1 - 2.9e-144 470.0 41.7 2.7e-17 63.1 0.3 14.8 2 2 14 16 16 16 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS85021.1 - 9.6e-125 405.5 32.8 1.3e-13 51.1 0.2 18.0 11 5 8 19 19 19 19 Ankyrin repeats (many copies) Ank PF00023.30 RUS85021.1 - 2.1e-109 353.6 59.4 1.9e-05 24.9 0.0 28.5 27 1 1 28 28 28 25 Ankyrin repeat Ank_3 PF13606.6 RUS85021.1 - 4.1e-107 337.0 36.2 0.00012 22.2 0.1 29.3 29 0 0 29 29 29 24 Ankyrin repeat Ank_5 PF13857.6 RUS85021.1 - 7.5e-105 341.6 42.8 3.1e-08 33.7 0.1 23.1 8 4 18 26 26 26 21 Ankyrin repeats (many copies) Ion_trans PF00520.31 RUS85021.1 - 9e-10 38.2 18.9 1.8e-09 37.2 18.9 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 RUS85021.1 - 0.014 14.1 12.8 0.032 12.9 12.8 1.6 1 1 0 1 1 1 0 Polycystin cation channel Helicase_PWI PF18149.1 RUS85021.1 - 0.035 14.3 0.0 12 6.2 0.0 3.3 3 0 0 3 3 3 0 N-terminal helicase PWI domain Cas_VVA1548 PF09652.10 RUS85021.1 - 0.12 12.7 0.0 1.5e+02 2.7 0.0 3.9 3 0 0 3 3 3 0 Putative CRISPR-associated protein (Cas_VVA1548) IPK PF03770.16 RUS85022.1 - 6.8e-52 176.2 0.9 4.4e-51 173.6 0.9 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase NHL PF01436.21 RUS85023.1 - 1.2e-43 144.9 17.1 5.7e-07 29.3 0.1 6.5 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 RUS85023.1 - 2.8e-15 56.3 0.9 1.2e-06 27.9 0.2 4.1 1 1 3 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 RUS85023.1 - 4.4e-13 49.4 0.4 0.00077 19.1 0.3 4.6 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Filamin PF00630.19 RUS85023.1 - 6.2e-13 49.5 0.0 2.2e-12 47.7 0.0 2.0 2 1 0 2 2 2 1 Filamin/ABP280 repeat zf-B_box PF00643.24 RUS85023.1 - 1.9e-08 34.3 4.4 1.9e-08 34.3 4.4 2.6 3 0 0 3 3 2 1 B-box zinc finger zf-C3HC4 PF00097.25 RUS85023.1 - 0.00018 21.3 3.0 0.00018 21.3 3.0 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS85023.1 - 0.00029 20.7 3.7 0.00029 20.7 3.7 2.8 2 0 0 2 2 2 1 zinc-RING finger domain DUF4934 PF16288.5 RUS85023.1 - 0.00072 19.4 0.8 0.044 13.7 0.2 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4934) zf-RING_2 PF13639.6 RUS85023.1 - 0.00082 19.7 3.6 0.00082 19.7 3.6 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS85023.1 - 0.0024 17.9 5.2 0.0034 17.4 3.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS85023.1 - 0.0067 16.3 3.9 0.0067 16.3 3.9 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS85023.1 - 0.0086 15.9 5.8 0.0086 15.9 5.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Invasin_D3 PF09134.10 RUS85023.1 - 0.0097 16.2 0.2 0.036 14.4 0.2 2.0 1 0 0 1 1 1 1 Invasin, domain 3 DUF839 PF05787.13 RUS85023.1 - 0.015 14.5 0.4 0.67 9.0 0.1 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF839) ATF7IP_BD PF16788.5 RUS85023.1 - 0.083 13.0 2.1 0.13 12.4 2.1 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain C1_2 PF03107.16 RUS85023.1 - 0.59 10.5 6.5 0.4 11.0 3.7 2.2 2 0 0 2 2 2 0 C1 domain VCBS PF13517.6 RUS85023.1 - 2.2 9.0 4.2 7.4 7.2 0.6 3.3 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-C3HC4_4 PF15227.6 RUS85023.1 - 6.2 7.1 14.5 0.063 13.4 4.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Caldesmon PF02029.15 RUS85024.1 - 5.1e-08 32.1 19.5 5.1e-08 32.1 19.5 1.1 1 0 0 1 1 1 1 Caldesmon Nop14 PF04147.12 RUS85024.1 - 0.00011 20.6 31.3 0.00013 20.4 31.3 1.0 1 0 0 1 1 1 1 Nop14-like family DDHD PF02862.17 RUS85024.1 - 0.0039 17.4 0.9 0.0039 17.4 0.9 1.2 1 0 0 1 1 1 1 DDHD domain BUD22 PF09073.10 RUS85024.1 - 0.01 15.2 31.7 0.013 14.9 31.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RUS85024.1 - 0.01 14.2 26.6 0.012 13.9 26.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 RUS85024.1 - 0.01 15.3 14.1 0.013 15.0 14.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mpp10 PF04006.12 RUS85024.1 - 0.032 12.7 38.9 0.046 12.2 38.9 1.2 1 0 0 1 1 1 0 Mpp10 protein RP-C_C PF11800.8 RUS85024.1 - 0.09 12.9 6.7 0.11 12.6 6.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SDA1 PF05285.12 RUS85024.1 - 0.1 12.0 38.1 0.13 11.6 38.1 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 RUS85024.1 - 0.13 11.0 17.9 0.15 10.8 17.9 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 RUS85024.1 - 0.13 11.0 19.6 0.17 10.6 19.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5308 PF17233.2 RUS85024.1 - 0.16 12.2 1.2 0.22 11.7 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Dynamin_N PF00350.23 RUS85024.1 - 0.17 11.9 2.5 0.21 11.6 2.5 1.3 1 0 0 1 1 1 0 Dynamin family ESM4 PF15952.5 RUS85024.1 - 0.21 12.0 5.1 0.25 11.7 5.1 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family Zip PF02535.22 RUS85024.1 - 0.29 10.3 9.4 0.32 10.2 9.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 RUS85024.1 - 0.34 11.2 22.2 0.46 10.8 22.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 RUS85024.1 - 0.35 9.6 21.3 0.45 9.3 21.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 RUS85024.1 - 0.54 10.0 29.5 0.72 9.6 29.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Drc1-Sld2 PF11719.8 RUS85024.1 - 0.66 9.4 26.1 0.83 9.1 26.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF3306 PF11748.8 RUS85024.1 - 0.74 10.7 22.6 1.2 10.0 22.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) BORG_CEP PF14957.6 RUS85024.1 - 0.83 10.8 7.9 1.2 10.3 7.9 1.4 1 0 0 1 1 1 0 Cdc42 effector DUF4045 PF13254.6 RUS85024.1 - 0.99 9.0 16.9 1.3 8.6 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.6 RUS85024.1 - 1.6 8.7 12.0 2.1 8.3 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Paf1 PF03985.13 RUS85024.1 - 1.9 7.4 45.5 2.6 6.9 45.5 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 RUS85024.1 - 2.3 6.2 50.7 2.9 5.9 50.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 RUS85024.1 - 2.3 8.6 16.5 3.8 7.9 16.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 MDM1 PF15501.6 RUS85024.1 - 2.3 7.3 29.9 3 6.9 29.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DDRGK PF09756.9 RUS85024.1 - 2.3 7.8 47.4 3.2 7.3 47.4 1.1 1 0 0 1 1 1 0 DDRGK domain XRN_M PF17846.1 RUS85024.1 - 2.4 7.0 19.3 3.4 6.5 19.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF2151 PF10221.9 RUS85024.1 - 2.9 6.4 15.3 3.4 6.1 15.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 RUS85024.1 - 3.2 6.4 16.8 3.7 6.2 16.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 RUS85024.1 - 3.8 5.5 15.5 4.3 5.3 15.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 RUS85024.1 - 4.7 6.1 12.8 5.8 5.8 12.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 IFT57 PF10498.9 RUS85024.1 - 5.9 5.8 27.9 7.9 5.3 27.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sec62 PF03839.16 RUS85024.1 - 6.1 6.3 18.1 8.1 5.9 18.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Trypan_PARP PF05887.11 RUS85024.1 - 6.3 6.8 33.5 10 6.1 33.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gti1_Pac2 PF09729.9 RUS85024.1 - 7.2 6.7 13.0 10 6.2 13.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF913 PF06025.12 RUS85024.1 - 8.3 5.3 16.0 11 4.9 16.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC27 PF09507.10 RUS85024.1 - 8.3 5.7 31.6 13 5.1 31.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MCM_bind PF09739.9 RUS85024.1 - 9.8 4.5 18.6 12 4.1 18.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cadherin PF00028.17 RUS85025.1 - 8e-91 298.7 6.3 2.3e-16 60.0 0.0 7.4 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS85025.1 - 1.3e-11 44.2 0.3 8.1e-08 32.0 0.0 4.8 5 0 0 5 5 5 1 Cadherin-like RET_CLD1 PF17756.1 RUS85025.1 - 0.00016 21.9 0.0 0.084 13.2 0.0 3.4 4 0 0 4 4 4 1 RET Cadherin like domain 1 DUF5527 PF17665.1 RUS85025.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Cadherin_C_2 PF16492.5 RUS85025.1 - 0.038 14.7 0.0 0.15 12.9 0.0 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PRIMA1 PF16101.5 RUS85025.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Orf78 PF06024.12 RUS85025.1 - 0.16 12.3 0.5 0.36 11.2 0.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Methyltr_RsmB-F PF01189.17 RUS85029.1 - 2.8e-05 23.8 0.1 0.00014 21.6 0.1 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Imm6 PF14434.6 RUS85029.1 - 0.17 11.8 0.1 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm6 VanY PF02557.17 RUS85029.1 - 1.2 9.0 3.4 8.6 6.2 0.2 2.8 1 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF4600 PF15372.6 RUS85030.1 - 1.5e-30 106.2 13.9 1.5e-30 106.2 13.9 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) Spc29 PF17082.5 RUS85030.1 - 0.00088 19.2 8.5 0.014 15.3 1.5 2.1 1 1 1 2 2 2 2 Spindle Pole Component 29 DUF4686 PF15742.5 RUS85030.1 - 0.0018 17.5 20.8 0.0021 17.2 20.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) EzrA PF06160.12 RUS85030.1 - 0.0038 15.5 17.9 0.0053 15.0 17.9 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TACC_C PF05010.14 RUS85030.1 - 0.0059 16.4 11.1 0.0059 16.4 11.1 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prefoldin_2 PF01920.20 RUS85030.1 - 0.0091 15.9 14.7 0.024 14.6 4.7 2.9 1 1 2 3 3 3 1 Prefoldin subunit DUF1664 PF07889.12 RUS85030.1 - 0.017 15.2 10.9 0.51 10.4 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 RUS85030.1 - 0.025 14.7 9.7 0.066 13.4 9.7 1.9 1 1 0 1 1 1 0 RasGAP C-terminus Fez1 PF06818.15 RUS85030.1 - 0.028 14.9 19.6 0.026 15.0 13.0 2.0 1 1 1 2 2 2 0 Fez1 DUF2681 PF10883.8 RUS85030.1 - 0.03 14.7 0.7 0.03 14.7 0.7 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF2681) DUF4200 PF13863.6 RUS85030.1 - 0.085 13.3 23.9 1.5 9.2 15.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 RUS85030.1 - 0.11 12.5 18.5 0.19 11.8 3.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 RUS85030.1 - 0.12 12.8 8.0 0.3 11.5 8.0 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB PspA_IM30 PF04012.12 RUS85030.1 - 0.14 11.7 17.2 0.057 13.0 10.2 2.2 1 1 0 2 2 2 0 PspA/IM30 family DUF745 PF05335.13 RUS85030.1 - 0.14 11.9 13.7 0.1 12.3 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) GAS PF13851.6 RUS85030.1 - 0.15 11.4 23.6 0.059 12.7 13.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1759 PF03564.15 RUS85030.1 - 0.15 12.0 4.4 0.1 12.5 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) MapZ_EC1 PF18041.1 RUS85030.1 - 0.18 12.0 7.2 0.15 12.3 2.8 2.2 1 1 1 2 2 2 0 MapZ extracellular domain 1 FlaC_arch PF05377.11 RUS85030.1 - 0.3 11.5 15.2 0.25 11.8 3.0 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 RUS85030.1 - 0.3 10.9 12.9 0.9 9.3 1.3 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 RUS85030.1 - 0.32 11.2 12.7 1.6 8.9 8.0 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family COMM_domain PF07258.14 RUS85030.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.8 3 0 0 3 3 3 0 COMM domain Bacillus_HBL PF05791.11 RUS85030.1 - 0.44 10.3 9.9 1.4 8.7 4.7 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 RUS85030.1 - 0.47 11.0 5.5 3.6 8.1 0.9 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BicD PF09730.9 RUS85030.1 - 0.56 8.6 18.9 0.41 9.0 2.3 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D HMMR_N PF15905.5 RUS85030.1 - 0.82 9.1 19.2 1.2 8.6 18.7 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF16 PF01519.16 RUS85030.1 - 0.88 10.1 11.9 1.9 9.0 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lectin_N PF03954.14 RUS85030.1 - 0.91 9.3 4.2 2.1 8.1 4.2 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TMF_TATA_bd PF12325.8 RUS85030.1 - 0.95 9.7 23.3 2.7 8.3 15.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1319 PF07028.11 RUS85030.1 - 1.1 9.6 7.2 2.8 8.2 3.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) KxDL PF10241.9 RUS85030.1 - 1.2 9.5 15.3 2.6 8.4 3.0 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein bZIP_1 PF00170.21 RUS85030.1 - 1.2 9.3 11.3 0.15 12.2 1.7 3.4 2 1 1 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.15 RUS85030.1 - 1.8 8.1 10.4 2.5 7.6 10.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 RUS85030.1 - 2.1 8.4 23.8 2.2 8.3 20.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 RUS85030.1 - 2.8 6.8 19.5 0.61 8.9 14.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 RUS85030.1 - 2.9 6.8 18.4 7.7 5.4 18.4 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 RUS85030.1 - 3.3 7.0 12.6 9.3 5.5 12.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 RUS85030.1 - 3.6 7.6 20.4 0.57 10.3 11.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.13 RUS85030.1 - 7.5 6.1 10.5 9.5 5.7 5.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region ERM PF00769.19 RUS85030.1 - 7.7 6.3 25.1 38 4.0 25.1 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PCRF PF03462.18 RUS85030.1 - 8.3 6.2 14.7 2.9e+02 1.2 14.5 2.1 1 1 0 1 1 1 0 PCRF domain JIP_LZII PF16471.5 RUS85030.1 - 8.3 6.7 14.0 2.3 8.5 9.5 2.1 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DHR10 PF18595.1 RUS85030.1 - 8.5 6.5 22.5 13 5.8 0.5 3.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain HLH PF00010.26 RUS85031.1 - 6e-16 58.1 3.1 1.2e-15 57.1 3.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS85031.1 - 5.3e-11 42.5 0.1 1.3e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Hairy Orange RNA_pol_Rpb4 PF03874.16 RUS85031.1 - 0.041 14.2 0.4 0.041 14.2 0.4 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Amidohydro_1 PF01979.20 RUS85032.1 - 1.9e-74 251.1 1.9 2.9e-74 250.4 1.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 RUS85032.1 - 6.5e-55 184.6 3.5 6.5e-55 184.6 3.5 2.1 3 0 0 3 3 3 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 RUS85032.1 - 2.7e-43 146.3 1.3 1.3e-42 144.1 0.2 2.3 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 RUS85032.1 - 1.7e-39 133.8 0.0 1.1e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 RUS85032.1 - 1.9e-06 27.7 2.7 2.8e-05 23.8 0.2 3.0 2 1 1 3 3 3 1 Amidohydrolase family Urease_linker PF18473.1 RUS85032.1 - 3.4e-05 23.6 0.1 0.0001 22.1 0.1 1.9 1 0 0 1 1 1 1 Urease subunit beta-alpha linker domain cobW PF02492.19 RUS85033.1 - 4.9e-30 104.4 0.0 6.1e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RUS85033.1 - 4.6e-06 25.8 0.2 0.0065 15.5 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 RUS85033.1 - 0.00095 19.7 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RUS85033.1 - 0.01 15.9 0.0 0.17 12.0 0.0 2.6 2 1 1 3 3 3 0 AAA domain (Cdc48 subfamily) AAA PF00004.29 RUS85033.1 - 0.015 15.7 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 RUS85033.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 RUS85033.1 - 0.02 15.3 0.0 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.15 RUS85033.1 - 0.045 13.7 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 RUS85033.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.17 RUS85033.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 RUS85033.1 - 0.49 9.5 3.2 1.1 8.3 0.2 2.1 1 1 1 2 2 2 0 NB-ARC domain Receptor_2B4 PF11465.8 RUS85035.1 - 0.071 13.3 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 SoxY PF13501.6 RUS85035.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Integrase_H2C2 PF17921.1 RUS85036.1 - 3e-22 78.5 0.1 5.6e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS85036.1 - 2.4e-20 72.9 0.0 4.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS85036.1 - 1.9e-06 28.0 0.0 5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RUS85036.1 - 2.9e-05 23.8 0.0 0.0001 22.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain DUF3295 PF11702.8 RUS85036.1 - 0.0056 16.1 7.7 0.0093 15.4 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) MLVIN_C PF18697.1 RUS85036.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PPP4R2 PF09184.11 RUS85036.1 - 0.13 11.9 5.5 0.19 11.3 5.5 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS85036.1 - 0.18 11.1 12.9 0.31 10.3 12.9 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RUS85036.1 - 0.34 10.6 22.5 0.7 9.6 22.5 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 RUS85036.1 - 0.42 10.6 8.7 0.62 10.0 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 RUS85036.1 - 1.9 7.4 4.0 3.2 6.6 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 RUS85036.1 - 3.2 5.9 10.1 5.2 5.2 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 RUS85036.1 - 3.4 7.7 5.2 11 6.0 5.2 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal PNISR PF15996.5 RUS85037.1 - 1.8e-47 162.2 23.0 1.8e-47 162.2 23.0 7.2 4 2 0 5 5 5 1 Arginine/serine-rich protein PNISR RT_RNaseH_2 PF17919.1 RUS85038.1 - 1.8e-32 111.4 0.1 5.4e-32 109.8 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS85038.1 - 7.8e-30 103.3 0.0 2.2e-29 101.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS85038.1 - 2.4e-17 63.2 0.0 6.1e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 RUS85038.1 - 4.2e-17 62.4 0.0 9.6e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS85038.1 - 1.6e-14 53.7 0.0 4.2e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain ECH_1 PF00378.20 RUS85038.1 - 7.3e-10 38.6 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS85038.1 - 1.6e-09 37.7 0.0 5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase gag-asp_proteas PF13975.6 RUS85038.1 - 1.8e-09 38.0 0.1 1.1e-08 35.5 0.0 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS85038.1 - 2.1e-07 31.5 0.2 8.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 RUS85038.1 - 1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 RUS85038.1 - 2.5e-05 24.4 0.0 6.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 RUS85038.1 - 5.4e-05 23.4 0.0 0.00031 21.0 0.0 2.4 3 0 0 3 3 2 1 Retrotransposon gag protein zf-C2H2_10 PF16588.5 RUS85038.1 - 0.041 13.6 3.3 0.082 12.7 3.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DNA_pol_viral_C PF00336.18 RUS85038.1 - 0.088 12.2 0.2 6 6.2 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Gpi16 PF04113.14 RUS85040.1 - 1.4e-155 518.9 0.2 1.1e-154 516.0 0.2 1.8 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AA_permease_2 PF13520.6 RUS85041.1 - 2.8e-61 207.7 35.2 3.4e-61 207.4 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS85041.1 - 7.2e-25 87.5 30.7 1e-24 87.0 30.7 1.3 1 1 0 1 1 1 1 Amino acid permease TMEM252 PF15664.5 RUS85042.1 - 0.0095 15.7 1.4 0.037 13.8 1.1 2.0 2 1 0 2 2 2 1 Transmembrane protein 252 family RRM_1 PF00076.22 RUS85043.1 - 9.2e-18 63.8 0.0 1.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SesA PF17107.5 RUS85043.1 - 0.11 12.7 0.2 0.17 12.1 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Arteri_Gl PF00951.18 RUS85044.1 - 0.033 14.0 0.4 0.048 13.5 0.4 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein SRTM1 PF15872.5 RUS85044.1 - 0.14 12.3 1.0 0.25 11.5 1.0 1.3 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 MPP6 PF10175.9 RUS85046.1 - 1.2e-32 113.2 12.3 1.7e-32 112.7 12.3 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 RUS85046.1 - 9.9e-05 21.1 10.8 0.00012 20.9 10.8 1.0 1 0 0 1 1 1 1 Utp14 protein Peptidase_M28 PF04389.17 RUS85048.1 - 4.3e-13 49.4 0.0 7.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 RUS85048.1 - 7.1e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Nicastrin PrlF_antitoxin PF15937.5 RUS85048.1 - 0.0083 16.6 0.3 0.026 15.0 0.1 1.9 2 0 0 2 2 2 1 prlF antitoxin for toxin YhaV_toxin AMP-binding PF00501.28 RUS85049.1 - 4.1e-24 84.9 0.0 6.6e-24 84.3 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme C2 PF00168.30 RUS85050.1 - 6.3e-09 36.0 0.1 8.7e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 C2 domain Imm2 PF14426.6 RUS85050.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm2 Lin-8 PF03353.15 RUS85052.1 - 9.5 5.7 7.4 12 5.4 7.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 RUS85053.1 - 9.1e-06 25.3 39.4 9.9e-06 25.2 39.4 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS85053.1 - 0.078 11.2 55.0 0.087 11.0 55.0 1.1 1 0 0 1 1 1 0 Nop14-like family Xan_ur_permease PF00860.20 RUS85054.1 - 3.4e-61 207.1 15.8 5.2e-61 206.5 15.8 1.2 1 0 0 1 1 1 1 Permease family MTABC_N PF16185.5 RUS85054.1 - 1.4 8.4 5.3 0.32 10.5 0.5 2.2 2 1 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Xan_ur_permease PF00860.20 RUS85055.1 - 1.9e-06 26.8 2.6 2.3e-06 26.6 2.6 1.0 1 0 0 1 1 1 1 Permease family HCMV_UL124 PF17609.2 RUS85055.1 - 0.086 13.0 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function Gal-3-0_sulfotr PF06990.11 RUS85056.1 - 3.5e-58 197.4 2.4 4.5e-58 197.0 2.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS85056.1 - 1.2e-05 25.3 1.3 2.2e-05 24.5 1.3 1.3 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 RUS85057.1 - 2e-54 185.0 0.9 2.5e-54 184.7 0.9 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Ig_3 PF13927.6 RUS85058.1 - 1.5e-09 38.3 0.1 2.4e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS85058.1 - 4.2e-09 36.3 0.2 7.1e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 RUS85058.1 - 4.8e-09 36.3 0.5 5.3e-08 33.0 0.5 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 RUS85058.1 - 2.8e-05 24.2 0.1 4.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS85058.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 RUS85058.1 - 0.0019 18.0 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR1 DUF4381 PF14316.6 RUS85058.1 - 0.018 15.3 0.2 0.04 14.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) BatD PF13584.6 RUS85058.1 - 0.039 12.8 0.0 0.045 12.6 0.0 1.3 1 1 0 1 1 1 0 Oxygen tolerance SKG6 PF08693.10 RUS85058.1 - 1.2 8.6 8.2 0.1 12.0 2.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Innexin PF00876.18 RUS85059.1 - 8.6e-17 61.4 1.0 1.7e-14 53.9 0.0 2.7 3 0 0 3 3 3 2 Innexin WD40 PF00400.32 RUS85060.1 - 2.2e-05 25.1 0.1 0.042 14.7 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Ras PF00071.22 RUS85062.1 - 1.8e-33 115.4 0.0 2.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85062.1 - 1e-08 35.4 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85062.1 - 9.2e-06 25.2 0.0 9.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS85062.1 - 0.00054 19.5 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CAS_C PF12026.8 RUS85063.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain HLH PF00010.26 RUS85064.1 - 4e-12 45.9 0.5 6.8e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.6 RUS85064.1 - 0.049 14.0 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 adh_short_C2 PF13561.6 RUS85067.1 - 2.8e-60 203.8 0.9 3.4e-60 203.5 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS85067.1 - 4.5e-43 147.0 1.1 5.3e-43 146.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS85067.1 - 0.00014 21.9 0.3 0.00021 21.3 0.3 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 RUS85067.1 - 0.0015 18.5 0.7 0.0035 17.3 0.7 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 RUS85067.1 - 0.0085 16.4 0.2 0.041 14.2 0.1 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glyco_trans_1_4 PF13692.6 RUS85067.1 - 0.029 14.8 0.3 0.083 13.3 0.1 1.8 2 1 0 2 2 2 0 Glycosyl transferases group 1 DUF2325 PF10087.9 RUS85067.1 - 0.038 14.1 0.2 0.092 12.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) KCNQ_channel PF03520.14 RUS85068.1 - 5.2e-25 88.4 0.0 1.1e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 RUS85068.1 - 1.6e-12 47.2 12.5 1.6e-12 47.2 11.5 1.4 1 1 0 1 1 1 1 Ion transport protein CD225 PF04505.12 RUS85068.1 - 0.17 12.0 5.1 1.3 9.2 1.5 3.3 1 1 1 2 2 2 0 Interferon-induced transmembrane protein IQ PF00612.27 RUS85068.1 - 4.4 7.4 5.7 0.58 10.1 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif Vac_ImportDeg PF09783.9 RUS85070.1 - 4.2e-06 26.7 1.0 1.9 8.3 0.1 3.9 1 1 3 4 4 4 3 Vacuolar import and degradation protein Trp_leader1 PF08055.11 RUS85070.1 - 0.83 9.4 27.8 29 4.5 0.1 7.6 8 0 0 8 8 8 0 Tryptophan leader peptide DUF2545 PF10810.8 RUS85070.1 - 2.7 8.2 17.1 8.5 6.6 0.1 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2545) TTD PF12148.8 RUS85070.1 - 7.1 6.5 17.0 8.7 6.2 0.2 5.7 1 1 6 7 7 7 0 Tandem tudor domain within UHRF1 NIF PF03031.18 RUS85071.1 - 3.7e-32 111.3 0.0 5.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ORC_WH_C PF18137.1 RUS85071.1 - 7.6 6.6 7.7 23 5.0 0.5 3.1 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal ChaC PF04752.12 RUS85072.1 - 1.6e-42 145.5 0.1 2.1e-42 145.2 0.1 1.2 1 0 0 1 1 1 1 ChaC-like protein DLH PF01738.18 RUS85072.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family EGF PF00008.27 RUS85073.1 - 1.1e-13 51.2 22.5 5.4e-08 33.0 3.5 2.9 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 RUS85073.1 - 1.2e-10 41.6 22.2 1.5e-06 28.6 5.1 3.2 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 RUS85073.1 - 3.4e-05 24.1 23.1 0.0074 16.6 5.8 2.8 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.7 RUS85073.1 - 0.00033 20.5 14.9 0.03 14.2 1.4 4.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS85073.1 - 0.0014 18.8 18.8 0.0093 16.2 5.8 3.0 3 0 0 3 3 3 2 Calcium-binding EGF domain SKG6 PF08693.10 RUS85073.1 - 0.0098 15.3 3.9 0.022 14.2 3.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 RUS85073.1 - 0.012 15.4 0.3 0.012 15.4 0.3 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Shisa PF13908.6 RUS85073.1 - 0.02 15.1 0.5 0.02 15.1 0.5 2.7 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator PTR2 PF00854.21 RUS85073.1 - 0.027 13.3 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 POT family EGF_alliinase PF04863.13 RUS85073.1 - 0.036 14.5 4.4 0.036 14.5 4.4 2.8 2 0 0 2 2 2 0 Alliinase EGF-like domain EphA2_TM PF14575.6 RUS85073.1 - 0.042 14.7 0.1 0.13 13.2 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FXa_inhibition PF14670.6 RUS85073.1 - 0.056 13.7 16.2 0.28 11.5 1.5 3.3 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site FAM176 PF14851.6 RUS85073.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Ly49 PF08391.10 RUS85073.1 - 0.074 13.4 0.5 0.15 12.4 0.5 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region NAD_binding_6 PF08030.12 RUS85073.1 - 0.1 12.7 1.2 0.16 12.1 1.1 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Laminin_EGF PF00053.24 RUS85073.1 - 0.14 12.3 17.1 2.7 8.2 7.6 2.8 1 1 1 2 2 2 0 Laminin EGF domain EGF_3 PF12947.7 RUS85073.1 - 0.4 10.9 18.7 0.49 10.6 4.9 2.7 2 0 0 2 2 2 0 EGF domain MNNL PF07657.13 RUS85074.1 - 1.7e-22 79.3 1.5 1.7e-22 79.3 1.5 4.3 3 1 2 5 5 5 1 N terminus of Notch ligand DSL PF01414.19 RUS85074.1 - 8.7e-22 77.2 6.9 8.7e-22 77.2 6.9 5.8 5 1 1 6 6 6 1 Delta serrate ligand EGF PF00008.27 RUS85074.1 - 3e-20 72.2 114.6 6.5e-08 32.7 6.0 8.9 7 1 2 9 9 9 6 EGF-like domain hEGF PF12661.7 RUS85074.1 - 1.1e-11 44.9 33.5 1.2e-06 28.9 5.5 9.7 9 1 1 10 10 10 4 Human growth factor-like EGF EGF_CA PF07645.15 RUS85074.1 - 0.00044 20.4 25.0 0.0025 18.0 11.5 8.4 4 2 4 8 8 8 3 Calcium-binding EGF domain EGF_2 PF07974.13 RUS85074.1 - 0.0039 17.5 133.5 0.0055 17.1 11.3 9.5 9 1 0 9 9 9 5 EGF-like domain cEGF PF12662.7 RUS85074.1 - 0.019 14.9 3.3 0.019 14.9 3.3 8.1 8 1 0 8 8 8 0 Complement Clr-like EGF-like SNF2_N PF00176.23 RUS85079.1 - 1.1e-68 231.6 1.1 3.6e-68 229.9 1.1 2.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 RUS85079.1 - 8.3e-46 155.7 26.3 8.3e-46 155.7 26.3 4.1 2 1 2 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 RUS85079.1 - 6.2e-18 65.2 0.2 3.1e-17 62.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS85079.1 - 2.8e-06 27.4 8.2 1.6e-05 25.0 0.0 4.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RUS85079.1 - 1.3e-05 24.5 12.2 1.8e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 RRM_1 PF00076.22 RUS85080.1 - 1.4e-29 101.7 0.1 1.1e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS85080.1 - 2.5e-05 24.2 0.3 0.0011 19.0 0.1 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 RUS85080.1 - 0.011 15.7 0.3 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RUS85080.1 - 0.056 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS85080.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif FEZ PF07763.13 RUS85081.1 - 2.7e-36 125.5 15.2 1.2e-35 123.4 15.2 1.8 1 1 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 RUS85081.1 - 0.012 15.6 0.9 0.019 15.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) NAD_binding_10 PF13460.6 RUS85081.1 - 0.043 13.7 0.2 0.089 12.7 0.2 1.4 1 1 0 1 1 1 0 NAD(P)H-binding zf-H3C2 PF16721.5 RUS85081.1 - 0.11 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding SBF2 PF12335.8 RUS85082.1 - 0.084 12.5 0.5 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Myotubularin protein Glycogen_syn PF05693.13 RUS85082.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase A_deaminase PF00962.22 RUS85083.1 - 8e-25 87.9 0.0 1.8e-24 86.7 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 RUS85083.1 - 3.9e-13 49.5 0.0 7.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Ins134_P3_kin_N PF17927.1 RUS85083.1 - 0.11 12.9 0.0 0.66 10.4 0.0 2.1 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DcpS_C PF11969.8 RUS85084.1 - 3.7e-30 104.7 0.2 8.4e-30 103.6 0.2 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 RUS85084.1 - 2.1e-20 73.5 0.2 8.7e-20 71.5 0.0 2.1 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal THAP PF05485.12 RUS85084.1 - 0.045 14.7 0.4 0.16 12.9 0.1 2.1 2 0 0 2 2 2 0 THAP domain Ras PF00071.22 RUS85085.1 - 2e-53 180.3 0.1 2.6e-53 180.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85085.1 - 2.1e-18 66.7 0.0 3.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85085.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS85085.1 - 7.9e-07 28.8 0.1 2.1e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS85085.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS85085.1 - 0.017 15.0 0.0 1 9.3 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 RUS85085.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.6 1 1 1 2 2 2 0 Ferrous iron transport protein B WW PF00397.26 RUS85086.1 - 3.6e-12 46.1 16.2 7.9e-07 29.1 3.9 2.7 2 0 0 2 2 2 2 WW domain DUF305 PF03713.13 RUS85086.1 - 2.5 8.2 7.6 0.38 10.9 1.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Orthopox_F7 PF05813.12 RUS85086.1 - 3.9 7.7 8.1 2.5 8.3 3.7 2.8 2 0 0 2 2 2 0 Orthopoxvirus F7 protein ABC_membrane PF00664.23 RUS85087.1 - 2.3e-55 188.2 11.1 4.3e-55 187.3 11.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS85087.1 - 2.8e-28 99.2 0.0 6.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS85087.1 - 2.2e-05 24.0 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain APS_kinase PF01583.20 RUS85087.1 - 0.0083 16.0 0.1 0.028 14.3 0.1 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 RUS85087.1 - 0.015 14.6 0.1 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 RUS85087.1 - 0.045 14.0 0.1 0.41 10.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RUS85087.1 - 0.086 12.4 0.1 0.7 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF4499 PF14934.6 RUS85088.1 - 3.8e-14 52.8 2.3 5.2e-14 52.3 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Ilm1 PF10311.9 RUS85090.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1772 PF08592.11 RUS85090.1 - 0.2 11.9 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Tetraspanin PF00335.20 RUS85091.1 - 2.2e-36 125.7 3.3 2.7e-36 125.4 3.3 1.0 1 0 0 1 1 1 1 Tetraspanin family SID-1_RNA_chan PF13965.6 RUS85091.1 - 0.0067 14.9 0.9 0.019 13.4 0.3 1.9 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 PIRT PF15099.6 RUS85091.1 - 0.083 12.5 0.1 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Cation_ATPase_C PF00689.21 RUS85091.1 - 0.38 10.4 7.4 0.63 9.7 5.8 1.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus PRA1 PF03208.19 RUS85091.1 - 1.3 8.7 0.0 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 PRA1 family protein Sigma_reg_N PF13800.6 RUS85091.1 - 2.5 8.5 6.8 53 4.2 0.2 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Amastin PF07344.11 RUS85091.1 - 4.9 7.0 14.9 9.1 6.1 0.0 2.9 2 1 0 2 2 2 0 Amastin surface glycoprotein Methyltransf_5 PF01795.19 RUS85092.1 - 3.7e-82 276.3 0.2 3.7e-81 273.0 0.2 1.9 1 1 0 1 1 1 1 MraW methylase family HHH_3 PF12836.7 RUS85092.1 - 0.0087 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Methyltransf_25 PF13649.6 RUS85092.1 - 0.051 14.3 0.1 4.6 8.0 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain SseC PF04888.12 RUS85092.1 - 0.076 12.6 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family THAP PF05485.12 RUS85094.1 - 4.7e-10 40.3 4.4 5.4e-10 40.1 0.9 2.6 1 1 1 2 2 2 1 THAP domain FPP PF05911.11 RUS85094.1 - 0.00063 18.1 0.4 0.00072 17.9 0.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Sugarporin_N PF11471.8 RUS85094.1 - 0.065 13.2 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF2975 PF11188.8 RUS85095.1 - 0.086 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) TERB2 PF15101.6 RUS85096.1 - 0.13 12.3 8.1 0.36 10.8 7.7 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 GREB1 PF15782.5 RUS85096.1 - 0.69 7.0 9.0 0.81 6.7 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 RUS85096.1 - 1.5 7.4 12.3 1.8 7.1 12.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.16 RUS85096.1 - 8.7 5.8 7.4 13 5.2 7.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Arm PF00514.23 RUS85097.1 - 0.00012 22.0 3.2 0.28 11.3 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 RUS85097.1 - 0.0091 16.1 0.4 6.1 7.0 0.0 2.7 3 1 0 3 3 3 2 V-ATPase subunit H V-ATPase_H_N PF03224.14 RUS85097.1 - 0.015 14.6 1.3 0.043 13.1 0.4 2.0 1 1 1 2 2 2 0 V-ATPase subunit H CHGN PF05679.16 RUS85098.1 - 6.5e-86 289.2 0.2 8e-86 288.9 0.2 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 RUS85098.1 - 3.6e-10 39.3 0.7 1.1e-09 37.9 0.7 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS85098.1 - 0.00059 19.4 0.1 0.011 15.3 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Androgen_recep PF02166.16 RUS85098.1 - 0.036 12.9 4.6 0.054 12.3 4.6 1.2 1 0 0 1 1 1 0 Androgen receptor MFS_1 PF07690.16 RUS85099.1 - 2.5e-39 135.2 59.0 6.7e-32 110.8 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RUS85099.1 - 3.5e-07 29.8 19.5 3e-06 26.8 19.5 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB RVT_1 PF00078.27 RUS85100.1 - 4.3e-20 72.2 0.0 6.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myosin_head PF00063.21 RUS85100.1 - 1.5e-08 33.3 0.0 1.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 RUS85100.1 - 0.00019 21.9 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS85100.1 - 0.0027 18.0 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RUS85100.1 - 0.032 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 RUS85100.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RUS85100.1 - 0.21 10.8 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Myosin_head PF00063.21 RUS85101.1 - 1.5e-55 188.7 0.0 2.4e-34 118.7 0.0 4.0 3 1 1 4 4 4 4 Myosin head (motor domain) CDC45 PF02724.14 RUS85101.1 - 9.1e-07 27.6 3.7 1.4e-06 26.9 3.7 1.2 1 0 0 1 1 1 1 CDC45-like protein IQ PF00612.27 RUS85101.1 - 0.00053 19.6 2.0 0.0024 17.5 2.0 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif TFIIA PF03153.13 RUS85101.1 - 1 9.3 32.5 2.4 8.0 32.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.12 RUS85101.1 - 1.1 7.8 25.8 1.2 7.7 23.5 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 RUS85101.1 - 1.8 6.6 37.3 2.8 5.9 37.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 RUS85101.1 - 3.4 6.5 12.7 5.6 5.9 12.7 1.2 1 0 0 1 1 1 0 Paf1 YL1 PF05764.13 RUS85101.1 - 4.6 7.3 28.4 11 6.0 28.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 RUS85101.1 - 5.2 5.2 25.4 7.6 4.6 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.14 RUS85101.1 - 6.5 5.3 16.2 11 4.5 16.2 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF1700 PF08006.11 RUS85102.1 - 0.13 11.8 8.3 0.19 11.3 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CRPA PF05745.11 RUS85102.1 - 0.32 11.0 6.6 0.57 10.2 6.6 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) fn3 PF00041.21 RUS85103.1 - 7.6e-05 23.0 0.4 0.00026 21.3 0.4 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS85103.1 - 0.00024 21.6 1.3 0.00098 19.7 0.5 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HSBP1 PF06825.12 RUS85103.1 - 0.021 14.7 0.4 0.11 12.3 0.4 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 RUS85103.1 - 0.074 13.1 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3835 PF12927.7 RUS85103.1 - 0.087 13.7 0.5 0.44 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) DUF333 PF03891.15 RUS85103.1 - 0.096 12.9 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF333) KxDL PF10241.9 RUS85103.1 - 0.16 12.3 1.8 0.42 10.9 1.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein MFS_1 PF07690.16 RUS85104.1 - 3.7e-34 118.2 37.3 4.6e-23 81.7 15.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF5560 PF17715.1 RUS85104.1 - 0.028 13.9 1.0 0.055 12.9 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5560) C1q PF00386.21 RUS85105.1 - 5.8e-14 52.4 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 C1q domain Ig_6 PF18452.1 RUS85105.1 - 0.004 16.7 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 RUS85105.1 - 0.013 16.0 0.0 0.038 14.6 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain FlgN PF05130.12 RUS85105.1 - 0.037 14.5 1.3 0.057 13.9 1.3 1.2 1 0 0 1 1 1 0 FlgN protein V-set PF07686.17 RUS85105.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin V-set domain ig PF00047.25 RUS85105.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain XhlA PF10779.9 RUS85105.1 - 0.22 11.7 0.6 0.38 11.0 0.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4207 PF13904.6 RUS85106.1 - 0.0024 17.6 2.2 0.0024 17.6 2.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Spt20 PF12090.8 RUS85106.1 - 0.015 14.9 7.0 0.018 14.7 7.0 1.2 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 RUS85106.1 - 0.15 11.3 1.7 0.2 10.9 1.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.14 RUS85106.1 - 0.86 9.5 6.1 1.3 8.9 6.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 RUS85106.1 - 0.9 8.6 2.9 1.2 8.1 2.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TMEM187 PF15100.6 RUS85107.1 - 2.2e-66 223.9 13.4 2.6e-66 223.7 13.4 1.0 1 0 0 1 1 1 1 TMEM187 protein family PNTB PF02233.16 RUS85107.1 - 0.53 9.1 2.3 0.76 8.6 2.3 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Kelch_5 PF13854.6 RUS85108.1 - 3.2e-30 103.6 0.6 3.6e-05 23.6 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS85108.1 - 2.3e-29 101.1 3.8 6e-05 23.2 0.0 7.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS85108.1 - 9.5e-27 92.8 0.7 2.4e-05 24.2 0.0 7.2 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS85108.1 - 1.9e-21 75.3 2.3 2.2e-05 24.0 0.0 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 RUS85108.1 - 3.4e-20 71.6 1.4 0.012 15.9 0.0 7.0 5 1 2 7 7 7 6 Kelch motif Kelch_2 PF07646.15 RUS85108.1 - 4.7e-17 61.2 1.0 0.0061 16.5 0.0 7.1 7 0 0 7 7 7 5 Kelch motif fn3 PF00041.21 RUS85108.1 - 7.8e-11 42.2 1.3 0.0016 18.8 0.0 4.6 5 0 0 5 5 5 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS85108.1 - 0.12 13.0 0.4 0.68 10.5 0.0 2.5 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain PMP1_2 PF08114.11 RUS85109.1 - 0.034 13.9 1.0 0.058 13.2 1.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Exo_endo_phos PF03372.23 RUS85110.1 - 3.8e-17 62.6 0.1 9.6e-17 61.3 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 RUS85110.1 - 3.8e-14 52.5 4.2 8.5e-14 51.4 4.2 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 RUS85110.1 - 0.00013 21.8 0.2 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Apt1 PF10351.9 RUS85111.1 - 0.19 10.6 13.0 0.31 9.8 13.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOBP PF15279.6 RUS85111.1 - 8.8 6.8 30.5 1.2 9.7 26.5 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein DUF736 PF05284.12 RUS85112.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF736) Tape_meas_lam_C PF09718.10 RUS85113.1 - 0.74 10.0 4.6 28 4.9 2.5 3.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 7tm_1 PF00001.21 RUS85114.1 - 9.9e-06 25.1 11.4 1.6e-05 24.3 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Fungus-induced PF10917.8 RUS85114.1 - 0.44 10.9 2.9 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 Fungus-induced protein Glyco_hydro_31 PF01055.26 RUS85115.1 - 2.3e-13 50.1 0.1 3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.26 RUS85116.1 - 3.6e-14 52.8 0.4 5.2e-14 52.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 SMI1_KNR4 PF09346.10 RUS85116.1 - 0.014 15.8 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Gal_mutarotas_2 PF13802.6 RUS85116.1 - 0.03 14.6 0.2 0.11 12.9 0.2 2.1 1 1 0 1 1 1 0 Galactose mutarotase-like DUF229 PF02995.17 RUS85118.1 - 5.5e-80 269.4 0.1 7.5e-80 268.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS85118.1 - 0.00019 21.0 0.2 0.0017 17.8 0.0 2.0 1 1 1 2 2 2 1 Sulfatase 7tm_1 PF00001.21 RUS85119.1 - 1.6e-14 53.9 0.0 2.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MtN3_slv PF03083.16 RUS85119.1 - 0.23 11.5 1.9 0.64 10.1 1.9 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Runt PF00853.19 RUS85120.1 - 3.1e-66 220.8 0.1 7.9e-66 219.5 0.0 1.7 2 0 0 2 2 2 1 Runt domain BAR_3 PF16746.5 RUS85121.1 - 8.5e-72 241.7 17.1 1.7e-71 240.7 17.1 1.5 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 RUS85121.1 - 6.5e-60 201.4 4.1 6.1e-39 133.3 0.4 2.6 2 0 0 2 2 2 2 RhoGAP domain PH PF00169.29 RUS85121.1 - 6.2e-08 33.1 0.4 1.4e-07 32.0 0.4 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 RUS85121.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS85121.1 - 0.00026 20.6 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nod1 PF17114.5 RUS85121.1 - 0.0027 17.9 1.7 2 8.6 0.1 2.8 2 0 0 2 2 2 2 Gef2-related medial cortical node protein Nod1 EloA-BP1 PF15870.5 RUS85121.1 - 0.038 14.3 1.4 0.12 12.6 1.4 1.8 1 0 0 1 1 1 0 ElonginA binding-protein 1 Mito_carr PF00153.27 RUS85122.1 - 4.4e-61 202.8 4.4 1e-21 76.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RUS85122.1 - 0.059 12.5 0.4 0.18 10.9 0.1 1.9 1 1 1 2 2 2 0 Gammaproteobacterial serine protease MFS_1 PF07690.16 RUS85123.1 - 3.5e-33 115.0 52.6 8.3e-20 71.0 23.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4902 PF16245.5 RUS85123.1 - 0.21 11.5 1.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4902) DDE_Tnp_IS1595 PF12762.7 RUS85124.1 - 0.01 15.9 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 2 0 ISXO2-like transposase domain Ras PF00071.22 RUS85125.1 - 1.3e-38 132.2 0.0 1.6e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85125.1 - 5e-23 81.6 0.0 7.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85125.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS85125.1 - 0.00071 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS85125.1 - 0.0016 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 RUS85125.1 - 0.0031 16.8 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 RUS85125.1 - 0.0048 16.3 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 RUS85125.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 RUS85125.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 RUS85125.1 - 0.042 12.9 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 RUS85125.1 - 0.042 14.1 0.0 0.081 13.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 RUS85125.1 - 0.049 13.2 0.1 2.9 7.4 0.1 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 RUS85125.1 - 0.069 12.6 0.2 0.4 10.1 0.0 2.0 2 1 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.6 RUS85125.1 - 0.081 12.6 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS85125.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.6 2 0 0 2 2 2 0 ABC transporter MH2 PF03166.14 RUS85126.1 - 3.6e-45 154.5 0.0 6.2e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 RUS85126.1 - 2e-22 79.3 0.0 4.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 MH1 domain DUF4813 PF16072.5 RUS85126.1 - 0.17 11.5 8.7 0.27 10.9 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Peptidase_S78_2 PF14550.6 RUS85127.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Putative phage serine protease XkdF 7tm_1 PF00001.21 RUS85129.1 - 1.5e-10 40.9 4.1 2.5e-10 40.1 4.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 RUS85129.1 - 3.3e-06 26.8 0.1 5.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7TM_GPCR_Srx PF10328.9 RUS85129.1 - 0.72 9.4 12.1 0.019 14.6 5.7 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-MYND PF01753.18 RUS85130.1 - 3.4e-08 33.4 13.5 3.4e-08 33.4 13.5 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 RUS85130.1 - 5.7 7.1 9.9 13 6.0 9.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ApoA-II PF04711.13 RUS85131.1 - 0.14 12.3 0.0 11 6.3 0.0 3.1 2 1 1 3 3 3 0 Apolipoprotein A-II (ApoA-II) F-box PF00646.33 RUS85133.1 - 6.8e-07 29.0 0.2 1.7e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS85133.1 - 4.1e-05 23.4 1.2 8.6e-05 22.3 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 RUS85133.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box ELO PF01151.18 RUS85134.1 - 1.8e-62 211.1 19.0 2.2e-62 210.8 19.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Med23 PF11573.8 RUS85135.1 - 0 1645.9 24.3 0 1645.7 24.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Profilin PF00235.19 RUS85136.1 - 3.8e-17 62.8 0.0 4.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Profilin Peroxin-13_N PF04088.13 RUS85137.1 - 4.7e-40 137.2 0.0 6.8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 RUS85137.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS85137.1 - 1e-05 25.1 0.0 2.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RUS85137.1 - 1.5e-05 24.5 0.0 3.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 RUS85138.1 - 1.5e-24 86.2 5.6 5.2e-16 58.8 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RUS85138.1 - 1.9e-22 77.1 10.4 1.8e-06 27.1 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 RUS85138.1 - 3.9e-20 70.0 3.9 6.7e-05 22.5 0.0 4.8 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RUS85138.1 - 5e-18 63.7 6.4 4e-06 26.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS85138.1 - 7.7e-15 54.5 7.9 5.5e-07 29.3 0.2 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS85138.1 - 5.8e-08 33.0 2.0 0.054 13.8 0.0 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS85138.1 - 1.9e-06 27.7 0.8 0.081 12.9 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 RUS85138.1 - 0.0085 15.9 3.0 0.78 9.7 0.0 3.7 4 1 1 5 5 5 1 EF hand DAG_kinase_N PF14513.6 RUS85138.1 - 0.01 16.1 0.5 0.014 15.6 0.5 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus Fe_hyd_SSU PF02256.17 RUS85138.1 - 0.024 14.7 0.1 9.6 6.4 0.0 2.8 2 1 0 2 2 2 0 Iron hydrogenase small subunit Caleosin PF05042.13 RUS85138.1 - 0.036 14.0 2.5 19 5.1 0.0 3.9 2 2 3 5 5 5 0 Caleosin related protein EF-hand_14 PF17959.1 RUS85138.1 - 0.056 13.8 2.8 3.4 8.1 0.2 3.1 3 1 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 RUS85138.1 - 0.057 13.6 0.5 0.77 10.0 0.4 2.2 1 1 1 2 2 2 0 Dockerin type I domain NADPH_Ox PF08414.10 RUS85138.1 - 0.073 13.4 1.4 2.5 8.5 0.2 2.4 1 1 0 2 2 2 0 Respiratory burst NADPH oxidase MecA_N PF05223.11 RUS85138.1 - 0.13 12.5 1.6 2.9 8.2 0.7 2.6 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Herpes_BLRF2 PF05812.12 RUS85139.1 - 0.00095 19.3 0.5 0.0018 18.4 0.4 1.5 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein Mut7-C PF01927.16 RUS85139.1 - 1.3 9.1 5.5 5.5 7.1 0.6 2.0 1 1 1 2 2 2 0 Mut7-C RNAse domain TPT PF03151.16 RUS85140.1 - 8.2e-17 61.5 21.4 1.2e-16 60.9 21.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PS_pyruv_trans PF04230.13 RUS85140.1 - 7.8e-16 58.8 0.1 1.8e-14 54.4 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase ATP-synt_I PF03899.15 RUS85140.1 - 4.1 7.8 11.1 1.7 9.1 0.5 3.3 3 1 0 3 3 3 0 ATP synthase I chain Pkinase PF00069.25 RUS85141.1 - 1.4e-49 168.9 5.4 6e-45 153.7 3.5 2.1 1 1 1 2 2 2 2 Protein kinase domain RCC1 PF00415.18 RUS85141.1 - 1.5e-37 128.0 22.7 2.3e-10 40.9 0.3 7.7 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 RUS85141.1 - 4e-36 124.6 3.8 1.5e-34 119.5 2.7 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase RCC1_2 PF13540.6 RUS85141.1 - 2.1e-22 78.4 22.7 5.6e-07 29.2 0.9 6.9 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 RUS85141.1 - 3.6e-05 22.9 2.0 5.7e-05 22.2 2.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS85141.1 - 0.0026 17.7 0.1 0.0058 16.6 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS85141.1 - 0.027 13.8 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS85141.1 - 0.077 11.8 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase 2-oxoacid_dh PF00198.23 RUS85142.1 - 2.5e-79 266.0 0.0 3.7e-79 265.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RUS85142.1 - 1.7e-18 66.2 0.0 3.9e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RUS85142.1 - 2e-15 56.8 0.2 2e-15 56.8 0.2 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RUS85142.1 - 0.014 15.2 0.0 0.49 10.2 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like Tctex-1 PF03645.13 RUS85143.1 - 3.1e-22 78.7 0.2 4e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M3 PF01432.20 RUS85144.1 - 8.8e-122 407.6 5.0 1.6e-83 281.5 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M3 TFIID_NTD2 PF04494.15 RUS85144.1 - 0.00065 19.9 0.6 1.1 9.5 0.1 2.8 2 1 0 2 2 2 2 WD40 associated region in TFIID subunit, NTD2 domain ADAM_CR_2 PF17771.1 RUS85146.1 - 1.3e-09 38.4 4.1 3.3e-09 37.1 4.1 1.7 1 0 0 1 1 1 1 ADAM cysteine-rich domain Reprolysin PF01421.19 RUS85146.1 - 6.4e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS85146.1 - 2.8e-05 24.4 0.0 6.8e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS85146.1 - 0.0044 17.5 0.0 0.016 15.7 0.0 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS85146.1 - 0.0049 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS85146.1 - 0.0067 16.3 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like 7tm_1 PF00001.21 RUS85147.1 - 1.5e-08 34.3 24.9 2.4e-07 30.4 24.4 2.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Trypsin_2 PF13365.6 RUS85148.1 - 3.1e-09 37.9 0.0 5.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2475 PF10629.9 RUS85149.1 - 4.4e-34 116.5 2.6 8e-34 115.7 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) PCDO_beta_N PF12391.8 RUS85149.1 - 0.032 13.8 0.3 2.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Med26 PF08711.11 RUS85150.1 - 4.8e-12 45.7 2.2 2.5e-11 43.4 0.1 2.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 RUS85150.1 - 1.1e-07 32.4 1.5 1.8e-07 31.6 1.5 1.6 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PBS_linker_poly PF00427.21 RUS85150.1 - 0.015 15.3 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Mago_nashi PF02792.14 RUS85150.1 - 0.039 14.1 0.4 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Mago nashi protein CR6_interact PF10147.9 RUS85151.1 - 1.4e-32 113.1 20.9 1.8e-32 112.7 20.9 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RF-1 PF00472.20 RUS85151.1 - 2.5 8.1 12.0 1.4 8.8 1.0 2.4 2 0 0 2 2 2 0 RF-1 domain PHD PF00628.29 RUS85152.1 - 2.1e-06 27.5 4.7 3.9e-06 26.7 4.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS85152.1 - 1.8e-05 24.2 3.9 3.5e-05 23.2 3.9 1.5 1 0 0 1 1 1 1 PHD-finger EF-hand_7 PF13499.6 RUS85153.1 - 2.6e-19 69.5 19.4 6.2e-07 29.8 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 RUS85153.1 - 3.9e-19 66.7 22.6 9.7e-05 21.6 2.5 6.8 6 1 1 7 7 7 6 EF hand EF-hand_6 PF13405.6 RUS85153.1 - 3e-16 57.9 14.6 0.024 14.5 1.1 6.8 5 1 1 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 RUS85153.1 - 2.9e-15 55.0 23.9 0.00025 20.4 0.7 6.4 6 1 1 7 7 7 5 EF hand EF-hand_8 PF13833.6 RUS85153.1 - 3.2e-07 30.1 23.4 0.0029 17.4 0.1 5.7 4 3 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS85153.1 - 0.00071 19.9 1.0 0.00071 19.9 1.0 3.6 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 RUS85153.1 - 0.0057 16.5 3.8 0.51 10.2 0.4 3.7 3 1 1 4 4 4 1 EF hand Tctex-1 PF03645.13 RUS85155.1 - 3.5e-26 91.4 0.2 4.6e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Tctex-1 family Tctex-1 PF03645.13 RUS85156.1 - 6.9e-28 96.9 0.0 7.8e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family PLAC8 PF04749.17 RUS85158.1 - 1.6e-22 80.3 5.0 1.9e-22 80.1 5.0 1.0 1 0 0 1 1 1 1 PLAC8 family EloA-BP1 PF15870.5 RUS85160.1 - 2.4e-50 171.0 0.4 2.4e-50 171.0 0.4 6.6 4 1 4 8 8 8 1 ElonginA binding-protein 1 DEP PF00610.21 RUS85163.1 - 5.2e-19 68.1 0.0 2.3e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_12 PF08461.10 RUS85163.1 - 0.028 14.3 2.1 0.072 13.1 0.6 2.0 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain SFTA2 PF15210.6 RUS85164.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Surfactant-associated protein 2 Thioredoxin PF00085.20 RUS85165.1 - 4.3e-32 110.2 0.1 4.6e-32 110.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS85165.1 - 4.2e-06 27.0 0.0 5.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS85165.1 - 2.7e-05 24.6 0.0 0.00031 21.2 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RUS85165.1 - 0.0001 22.4 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 RUS85165.1 - 0.00028 20.4 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RUS85165.1 - 0.002 18.0 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS85165.1 - 0.0092 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin CM2 PF03021.14 RUS85165.1 - 0.074 12.9 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M2 protein Thioredoxin PF00085.20 RUS85166.1 - 2.7e-27 94.7 0.1 3.3e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS85166.1 - 1.1e-06 28.9 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS85166.1 - 2.7e-06 27.8 0.0 6.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RUS85166.1 - 0.00029 20.7 0.0 0.00031 20.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS85166.1 - 0.00054 19.7 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 RUS85166.1 - 0.0014 18.1 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 RUS85166.1 - 0.013 15.7 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 RUS85166.1 - 0.065 13.5 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 RUS85167.1 - 1.3e-32 111.9 0.6 1.5e-32 111.6 0.6 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS85167.1 - 5.1e-07 29.9 0.0 6.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS85167.1 - 2.9e-05 24.5 0.1 0.00035 21.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RUS85167.1 - 4.7e-05 23.5 0.1 7.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RUS85167.1 - 7.9e-05 22.6 0.1 8.5e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RUS85167.1 - 0.00029 20.6 0.1 0.00031 20.5 0.1 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 RUS85167.1 - 0.0035 17.2 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 RUS85167.1 - 0.005 16.2 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family UPF0158 PF03682.13 RUS85167.1 - 0.0055 16.7 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0158) DIM1 PF02966.16 RUS85167.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_9 PF14595.6 RUS85167.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 RUS85167.1 - 0.037 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF2703 PF10865.8 RUS85167.1 - 0.098 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DUF4566 PF15130.6 RUS85168.1 - 4.9e-112 372.8 0.9 5.5e-112 372.7 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) BNR_3 PF13859.6 RUS85169.1 - 0.084 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 BNR repeat-like domain Carboxyl_trans PF01039.22 RUS85170.1 - 7.1e-94 315.2 0.0 8.6e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Laminin_G_2 PF02210.24 RUS85171.1 - 3.1e-83 276.6 13.7 3.1e-21 76.3 0.8 6.4 6 0 0 6 6 6 6 Laminin G domain Laminin_G_1 PF00054.23 RUS85171.1 - 1.3e-58 196.9 2.0 1.5e-18 67.3 0.1 6.7 6 1 0 6 6 6 6 Laminin G domain Laminin_G_3 PF13385.6 RUS85171.1 - 5.2e-18 65.6 2.7 0.0064 16.7 0.0 6.4 6 0 0 6 6 6 5 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RUS85171.1 - 6.7e-07 29.5 61.3 6.9e-05 23.1 5.7 5.4 5 0 0 5 5 5 3 EGF-like domain DUF1180 PF06679.12 RUS85171.1 - 0.099 13.1 4.5 0.63 10.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 RUS85171.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family SIT PF15330.6 RUS85171.1 - 0.11 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Syndecan PF01034.20 RUS85171.1 - 0.2 11.6 3.2 0.14 12.0 1.0 1.8 2 0 0 2 2 2 0 Syndecan domain RrnaAD PF00398.20 RUS85173.1 - 1.3e-42 145.7 0.0 1.8e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Linker_histone PF00538.19 RUS85174.1 - 7.7e-08 32.6 3.2 0.018 15.4 0.0 3.8 3 0 0 3 3 3 2 linker histone H1 and H5 family SAM_1 PF00536.30 RUS85174.1 - 0.052 14.0 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ldh_2 PF02615.14 RUS85175.1 - 3.8e-114 381.3 0.5 4.6e-114 381.0 0.5 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Glutaredoxin PF00462.24 RUS85176.1 - 3.5e-17 62.4 0.1 5.7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 RUS85176.1 - 2.9e-09 36.9 0.0 5.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GST_N_3 PF13417.6 RUS85176.1 - 0.0012 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 RUS85176.1 - 0.015 15.4 0.0 2.6 8.2 0.1 3.2 3 1 1 4 4 4 0 Thioredoxin GATA PF00320.27 RUS85177.1 - 1.9e-08 33.8 0.9 3.8e-08 32.8 0.9 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-C2H2_11 PF16622.5 RUS85177.1 - 0.99 9.2 3.2 2.1 8.2 0.7 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Mito_carr PF00153.27 RUS85178.1 - 3.9e-66 219.0 5.5 1.9e-21 75.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Tetraspanin PF00335.20 RUS85179.1 - 8.5e-24 84.5 11.8 1e-23 84.3 11.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Ac76 PF05814.11 RUS85179.1 - 7.9 6.6 8.2 1.4 9.0 3.5 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) Bmt2 PF11968.8 RUS85180.1 - 0.005 16.7 0.6 0.0054 16.6 0.6 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Peptidase_S49_N PF08496.10 RUS85180.1 - 0.098 12.7 1.3 0.12 12.5 1.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Osteoregulin PF07175.11 RUS85180.1 - 0.11 12.7 3.5 0.13 12.4 3.5 1.1 1 0 0 1 1 1 0 Osteoregulin Zip PF02535.22 RUS85180.1 - 0.2 10.9 2.7 0.22 10.7 2.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter GST_N PF02798.20 RUS85182.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS85182.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RB_A PF01858.17 RUS85183.1 - 1.1e-56 191.8 10.4 3.6e-56 190.1 0.1 3.7 4 0 0 4 4 4 2 Retinoblastoma-associated protein A domain RB_B PF01857.20 RUS85183.1 - 1.4e-32 112.5 5.3 1.4e-32 112.5 5.3 2.6 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 RUS85183.1 - 8.8e-14 51.2 0.0 3.1e-12 46.2 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) tRNA-synt_1g PF09334.11 RUS85185.1 - 4.5e-147 489.9 0.1 5.8e-147 489.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 RUS85185.1 - 5.7e-27 93.6 19.4 1.7e-13 50.5 5.2 2.9 2 0 0 2 2 2 2 WHEP-TRS domain GST_N_5 PF18485.1 RUS85185.1 - 3.4e-16 59.4 0.0 9.7e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain tRNA-synt_1 PF00133.22 RUS85185.1 - 1.2e-07 30.4 0.3 0.001 17.4 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RUS85185.1 - 1.8e-05 24.8 0.1 5.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA GST_C_6 PF17171.4 RUS85185.1 - 7.5e-05 22.4 0.0 0.00019 21.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS85185.1 - 0.0015 18.7 0.0 0.0055 16.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS85185.1 - 0.0048 17.1 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RUS85185.1 - 0.066 12.5 0.0 0.55 9.5 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain HTH_23 PF13384.6 RUS85185.1 - 0.073 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain NAPRTase_C PF17956.1 RUS85185.1 - 0.089 13.2 0.5 11 6.5 0.2 2.5 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF16 PF01519.16 RUS85185.1 - 0.62 10.6 5.0 15 6.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 zinc-ribbons_6 PF07191.12 RUS85185.1 - 1.6 8.8 4.8 3.9 7.5 4.8 1.7 1 0 0 1 1 1 0 zinc-ribbons RNA_pol_3_Rpc31 PF11705.8 RUS85187.1 - 0.00063 20.1 34.0 0.0008 19.7 34.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 RUS85187.1 - 0.0024 17.7 32.0 0.0028 17.5 32.0 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein BUD22 PF09073.10 RUS85187.1 - 0.0027 17.1 32.5 0.0031 16.9 32.5 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 RUS85187.1 - 0.009 14.3 29.9 0.0093 14.2 29.9 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_polI_A34 PF08208.11 RUS85187.1 - 0.088 12.9 38.4 0.11 12.6 38.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.8 RUS85187.1 - 0.1 11.4 19.6 0.14 10.9 19.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 RUS85187.1 - 0.11 11.4 13.8 0.12 11.3 13.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 RUS85187.1 - 0.12 12.2 12.0 0.13 12.2 12.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nha1_C PF08619.10 RUS85187.1 - 0.12 11.5 32.0 0.14 11.3 32.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM60A PF15396.6 RUS85187.1 - 0.13 12.2 15.5 0.13 12.3 15.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A SpoIIP PF07454.11 RUS85187.1 - 0.13 11.7 17.9 0.14 11.6 17.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 RUS85187.1 - 0.15 11.1 35.8 0.16 11.0 35.8 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 RUS85187.1 - 0.17 11.3 31.9 0.2 11.1 31.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 RUS85187.1 - 0.23 11.4 18.2 0.26 11.2 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 RUS85187.1 - 0.34 10.0 18.4 0.33 10.1 18.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Spore_coat_CotO PF14153.6 RUS85187.1 - 0.65 9.9 25.9 0.66 9.9 25.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1754 PF08555.10 RUS85187.1 - 0.77 10.6 41.3 1.1 10.1 41.3 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Presenilin PF01080.17 RUS85187.1 - 1 8.1 22.4 1.1 8.0 22.4 1.0 1 0 0 1 1 1 0 Presenilin DUF5308 PF17233.2 RUS85187.1 - 1 9.6 6.0 1.2 9.4 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Cellulose_synt PF03552.14 RUS85187.1 - 1.1 7.7 10.2 1.2 7.6 10.2 1.0 1 0 0 1 1 1 0 Cellulose synthase FGF-BP1 PF06473.12 RUS85187.1 - 1.1 9.0 19.8 1.3 8.8 19.8 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DDHD PF02862.17 RUS85187.1 - 1.3 9.1 10.2 1.5 8.9 10.2 1.3 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 RUS85187.1 - 1.7 7.8 14.3 1.6 7.8 14.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Spem1 PF15670.5 RUS85187.1 - 1.7 8.1 10.5 1.9 8.0 10.5 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 BORG_CEP PF14957.6 RUS85187.1 - 2.9 9.1 12.8 3 9.0 12.8 1.1 1 0 0 1 1 1 0 Cdc42 effector V_ATPase_I PF01496.19 RUS85187.1 - 3.2 5.6 22.0 3.7 5.4 22.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.9 RUS85187.1 - 3.7 7.6 16.6 4.3 7.4 16.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 RUS85187.1 - 4.3 6.0 31.2 5.1 5.8 31.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 RUS85187.1 - 4.6 6.2 15.6 4.6 6.2 15.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 RUS85187.1 - 4.9 6.5 7.6 5.1 6.5 7.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 RUS85187.1 - 5 5.4 8.8 4.8 5.5 8.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSRNP_N PF16019.5 RUS85187.1 - 5.1 6.9 19.3 6.3 6.6 19.3 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus NARP1 PF12569.8 RUS85187.1 - 6 5.7 28.9 6.8 5.5 28.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 RUS85187.1 - 7.4 6.5 37.7 11 5.9 37.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 RUS85187.1 - 7.9 6.0 35.0 8.9 5.8 35.0 1.1 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 RUS85187.1 - 8 5.1 17.9 7.9 5.1 17.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lipase PF00151.19 RUS85189.1 - 4e-88 296.0 0.0 5.1e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS85189.1 - 0.00033 21.3 0.2 0.00052 20.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RUS85189.1 - 0.00072 19.1 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 RUS85189.1 - 0.079 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Stanniocalcin PF03298.13 RUS85190.1 - 1.7e-08 34.0 0.4 2.2e-08 33.7 0.4 1.1 1 0 0 1 1 1 1 Stanniocalcin family rve PF00665.26 RUS85191.1 - 5.3e-19 68.6 0.0 8.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS85191.1 - 1.2e-05 25.0 0.3 9e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain AAA_lid_3 PF17862.1 RUS85191.1 - 1.2e-05 25.0 0.1 3.3e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 AAA+ lid domain Orai-1 PF07856.12 RUS85191.1 - 0.0084 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF4128 PF13554.6 RUS85191.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function TTL PF03133.15 RUS85192.1 - 2.1e-51 174.8 3.2 3.3e-51 174.2 3.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS85192.1 - 0.0016 17.8 0.1 0.0061 15.8 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp TRAM_LAG1_CLN8 PF03798.16 RUS85192.1 - 0.025 14.3 0.2 0.057 13.1 0.2 1.6 1 0 0 1 1 1 0 TLC domain TcpQ PF10671.9 RUS85192.1 - 0.11 12.6 0.2 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q F-box-like PF12937.7 RUS85193.1 - 5.8e-08 32.5 0.5 1.1e-07 31.7 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS85193.1 - 3.3e-06 26.8 2.0 7.6e-06 25.7 2.0 1.7 1 1 0 1 1 1 1 F-box domain PapD_C PF02753.17 RUS85194.1 - 3.7 8.0 5.8 10 6.5 0.2 2.9 2 1 1 3 3 3 0 Pili assembly chaperone PapD, C-terminal domain CC190 PF15768.5 RUS85194.1 - 5 7.1 17.8 8.5 6.3 17.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 DUF2138 PF09909.9 RUS85195.1 - 0.077 11.3 0.0 0.084 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) MFS_1 PF07690.16 RUS85196.1 - 2.2e-29 102.5 30.7 7.8e-24 84.2 19.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS85196.1 - 1.5e-06 27.4 17.5 5.1e-05 22.3 1.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter GKAP PF03359.13 RUS85197.1 - 0.13 11.8 5.1 0.21 11.1 5.1 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Peptidase_S49_N PF08496.10 RUS85197.1 - 0.26 11.4 2.9 0.46 10.5 2.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nic96 PF04097.14 RUS85198.1 - 1.5e-183 611.7 0.1 1.8e-183 611.4 0.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Vps39_1 PF10366.9 RUS85198.1 - 0.017 15.4 0.1 0.069 13.4 0.1 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.6 RUS85198.1 - 0.027 15.0 0.0 13 6.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS85198.1 - 0.063 14.1 0.1 30 5.8 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 RUS85198.1 - 2.6 8.5 8.2 58 4.3 0.0 5.1 5 1 1 6 6 6 0 PPR repeat PARP PF00644.20 RUS85200.1 - 1.1e-14 54.4 0.0 1.1e-14 54.4 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 RUS85200.1 - 1.6e-05 24.7 0.6 0.00097 18.9 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macro PF01661.21 RUS85200.1 - 0.00021 21.3 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 Macro domain DUF3990 PF13151.6 RUS85200.1 - 0.0012 18.6 0.0 0.0043 16.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) GST_N_4 PF17172.4 RUS85201.1 - 0.21 12.4 2.8 4.2 8.2 0.4 4.9 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Mod_r PF07200.13 RUS85202.1 - 3.4e-35 121.3 13.0 4.2e-35 121.0 13.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PH PF00169.29 RUS85203.1 - 0.00011 22.7 0.0 0.00036 21.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RUS85203.1 - 0.0042 17.4 0.1 0.017 15.4 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Conotoxin_I2 PF17557.2 RUS85203.1 - 2 8.6 4.8 0.61 10.2 0.6 2.0 2 0 0 2 2 2 0 I2-superfamily conotoxins FAM47 PF14642.6 RUS85204.1 - 3.4e-11 43.2 0.1 8.2e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 FAM47 family Pkinase PF00069.25 RUS85205.1 - 3.3e-59 200.4 0.0 7.4e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85205.1 - 2.3e-40 138.5 0.0 4.4e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS85205.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS85205.1 - 0.00024 20.0 1.5 0.00074 18.4 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase BrnA_antitoxin PF14384.6 RUS85205.1 - 1.2 9.7 5.6 0.52 10.8 1.5 2.7 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system RNA_ligase PF09414.10 RUS85206.1 - 3.7e-16 59.9 0.3 2.4e-14 54.0 0.3 2.1 1 1 0 1 1 1 1 RNA ligase DUF1184 PF06683.11 RUS85206.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) T4_Rnl2_C PF18043.1 RUS85207.1 - 0.0017 18.4 0.1 0.0037 17.4 0.1 1.6 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal RTX_C PF08339.10 RUS85207.1 - 0.063 13.3 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 RTX C-terminal domain Phasin PF05597.11 RUS85207.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-H2C2_5 PF13909.6 RUS85208.1 - 3.8e-06 26.5 1.9 3.8e-06 26.5 1.9 3.2 4 0 0 4 4 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS85208.1 - 5e-05 23.8 20.7 0.006 17.3 2.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS85208.1 - 0.0004 20.3 4.2 0.0004 20.3 4.2 2.7 3 1 0 3 3 3 1 C2H2-type zinc finger OrsD PF12013.8 RUS85208.1 - 0.0009 19.7 3.1 0.078 13.4 0.0 2.9 2 1 1 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_2 PF13465.6 RUS85208.1 - 0.01 16.2 20.7 0.051 14.0 0.9 5.0 5 0 0 5 5 5 0 Zinc-finger double domain zf-Di19 PF05605.12 RUS85208.1 - 0.016 15.5 13.2 0.46 10.8 8.2 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 RUS85208.1 - 0.025 14.9 1.4 0.059 13.7 1.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 RUS85208.1 - 0.025 14.2 0.0 0.025 14.2 0.0 2.9 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 RUS85208.1 - 0.043 14.1 11.3 4.7 7.6 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Glutaredoxin PF00462.24 RUS85208.1 - 0.094 12.9 0.3 0.31 11.3 0.3 1.9 1 0 0 1 1 1 0 Glutaredoxin zf-Sec23_Sec24 PF04810.15 RUS85208.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF3795 PF12675.7 RUS85208.1 - 0.17 12.3 1.7 3.9 8.0 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) zinc_ribbon_10 PF10058.9 RUS85208.1 - 0.43 10.4 2.5 5.3 6.8 0.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2 PF00096.26 RUS85208.1 - 1 9.9 22.2 4.6 7.9 2.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Elf1 PF05129.13 RUS85208.1 - 1.7 8.7 7.5 11 6.1 1.1 3.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-XS PF03470.14 RUS85208.1 - 2.6 8.4 7.4 0.54 10.6 2.4 2.4 2 0 0 2 2 2 0 XS zinc finger domain DUF1647 PF07801.11 RUS85209.1 - 3.7e-12 46.2 0.1 9.7e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Phos_pyr_kin PF08543.12 RUS85210.1 - 6.1e-17 61.8 0.0 7.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 RUS85210.1 - 7.3e-12 45.2 0.1 1.5e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase CDC37_M PF08565.11 RUS85211.1 - 1.6e-26 92.5 0.4 1.6e-26 92.5 0.4 2.8 2 1 1 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 RUS85211.1 - 2.3e-14 54.4 21.3 2.3e-14 54.4 21.3 2.7 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 RUS85211.1 - 2.1e-12 47.0 0.1 2.1e-12 47.0 0.1 4.1 3 2 1 4 4 4 1 Cdc37 C terminal domain V_ATPase_I PF01496.19 RUS85211.1 - 0.2 9.5 12.2 0.36 8.7 12.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 RUS85211.1 - 0.29 10.5 9.0 1.1 8.6 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LodA_N PF17990.1 RUS85211.1 - 2.4 8.0 5.4 4 7.3 5.4 1.3 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal Protocadherin PF08374.11 RUS85211.1 - 3.9 7.4 10.2 8.2 6.3 10.2 1.6 1 0 0 1 1 1 0 Protocadherin NEMP PF10225.9 RUS85211.1 - 5.9 6.5 9.6 14 5.3 0.3 2.4 2 0 0 2 2 2 0 NEMP family DUF572 PF04502.13 RUS85211.1 - 9.1 5.8 27.4 12 5.5 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ank_5 PF13857.6 RUS85212.1 - 8.2e-13 48.3 1.1 2.1e-08 34.3 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS85212.1 - 1.6e-09 38.1 2.7 0.00036 21.0 0.1 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS85212.1 - 2.4e-06 28.0 5.7 0.01 16.4 0.2 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS85212.1 - 2.6e-06 27.3 3.2 0.049 14.2 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS85212.1 - 1.9e-05 24.9 7.4 0.15 12.5 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeat Retrotran_gag_2 PF14223.6 RUS85212.1 - 0.022 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ank_4 PF13637.6 RUS85213.1 - 2.1e-08 34.6 0.5 2.4e-05 24.8 0.1 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS85213.1 - 0.00016 22.2 0.0 0.00058 20.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS85213.1 - 0.0037 17.6 0.4 0.013 15.8 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS85213.1 - 0.0042 17.5 0.0 0.069 13.6 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 RUS85213.1 - 0.062 13.9 0.1 1.6 9.5 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Thiolase_N PF00108.23 RUS85216.1 - 1.6e-86 289.9 0.4 2.3e-86 289.3 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS85216.1 - 1.6e-44 150.5 0.2 2.1e-42 143.7 0.2 2.4 2 0 0 2 2 2 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RUS85216.1 - 9.7e-06 25.3 2.9 0.00022 20.9 2.1 2.6 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RUS85216.1 - 1 9.3 5.9 4.3 7.3 0.2 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cid2 PF09774.9 RUS85217.1 - 4.5e-14 53.2 2.4 1.4e-12 48.3 2.4 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF2353 PF09789.9 RUS85217.1 - 0.004 16.6 0.3 0.0041 16.5 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Caldesmon PF02029.15 RUS85217.1 - 0.13 11.0 0.3 0.14 10.8 0.3 1.0 1 0 0 1 1 1 0 Caldesmon E1_DerP2_DerF2 PF02221.15 RUS85218.1 - 1.6e-14 54.4 0.2 2.5e-14 53.9 0.2 1.2 1 0 0 1 1 1 1 ML domain Galactosyl_T PF01762.21 RUS85219.1 - 3e-31 108.8 0.0 4e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase DUF3011 PF11218.8 RUS85220.1 - 6.6e-19 68.7 0.1 1.6e-05 25.0 0.0 5.2 3 1 1 4 4 4 4 Protein of unknown function (DUF3011) Lustrin_cystein PF14625.6 RUS85220.1 - 0.0014 19.0 3.4 0.0014 19.0 3.4 4.0 3 0 0 3 3 3 2 Lustrin, cysteine-rich repeated domain p450 PF00067.22 RUS85221.1 - 6.5e-148 493.3 0.9 3.3e-98 329.4 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Adeno_terminal PF02459.15 RUS85221.1 - 0.0076 14.7 0.0 0.2 10.0 0.0 2.0 2 0 0 2 2 2 2 Adenoviral DNA terminal protein DUF2160 PF09928.9 RUS85221.1 - 0.049 13.9 0.5 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) RNase_H PF00075.24 RUS85223.1 - 5.5e-06 26.6 0.0 9.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RT_RNaseH PF17917.1 RUS85223.1 - 0.0094 16.2 0.1 1.8 8.9 0.2 2.6 2 1 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 RUS85223.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Myb_DNA-bind_3 PF12776.7 RUS85223.1 - 0.2 12.6 3.2 4.6 8.3 0.0 3.5 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain BTB PF00651.31 RUS85225.1 - 6.3e-19 68.2 0.4 1.4e-18 67.2 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 RUS85225.1 - 3.4e-12 45.7 1.2 4e-07 29.5 0.0 4.4 4 0 0 4 4 4 2 Kelch motif BACK PF07707.15 RUS85225.1 - 5.5e-12 45.7 0.6 1.8e-11 44.0 0.6 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS85225.1 - 9e-11 41.7 0.2 7.5e-07 29.2 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RUS85225.1 - 0.00014 21.7 3.7 0.00031 20.6 0.0 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 RUS85225.1 - 0.0026 17.7 3.0 0.004 17.1 0.2 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 RUS85225.1 - 0.0037 17.2 1.2 0.48 10.5 0.4 3.5 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS85225.1 - 0.0041 17.4 0.0 1.7 9.0 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain AKAP2_C PF15304.6 RUS85226.1 - 0.0015 17.9 1.9 0.0015 17.9 1.9 7.1 2 2 2 6 6 6 4 A-kinase anchor protein 2 C-terminus WD40 PF00400.32 RUS85228.1 - 3.2e-25 87.9 6.3 4.9e-05 24.0 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85228.1 - 5e-06 26.7 0.1 0.019 15.2 0.0 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RUS85228.1 - 2e-05 24.9 0.2 0.0028 18.1 0.0 3.2 3 0 0 3 3 3 1 PQQ-like domain PALB2_WD40 PF16756.5 RUS85228.1 - 7.1e-05 21.9 0.6 0.015 14.2 0.3 3.3 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Utp8 PF10395.9 RUS85228.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Utp8 family PQQ PF01011.21 RUS85228.1 - 0.32 11.0 1.6 4.8 7.3 0.8 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Orn_Arg_deC_N PF02784.16 RUS85229.1 - 9.5e-70 234.8 0.0 1.3e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RUS85229.1 - 2.1e-19 69.6 0.0 2.8e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-RING_11 PF17123.5 RUS85231.1 - 0.074 12.8 0.3 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger Tristanin_u2 PF16638.5 RUS85232.1 - 0.011 16.5 0.2 0.017 16.0 0.2 1.3 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Med13_C PF06333.12 RUS85232.1 - 0.061 12.6 9.1 0.072 12.4 9.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain WD40 PF00400.32 RUS85233.1 - 9.7e-14 51.6 3.8 1.1e-05 26.0 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Phg_2220_C PF09524.10 RUS85233.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) FAF PF11250.8 RUS85233.1 - 0.21 11.9 0.0 14 6.0 0.0 2.6 2 1 0 2 2 2 0 Fantastic Four meristem regulator LRR_4 PF12799.7 RUS85234.1 - 9.1e-19 67.3 26.0 3.5e-05 24.1 8.3 4.8 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS85234.1 - 3.3e-12 46.0 26.7 3.3e-05 23.5 2.5 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RUS85234.1 - 3.5e-11 42.9 4.6 2.2e-05 24.0 0.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RUS85234.1 - 0.018 15.1 19.5 2 8.7 1.8 5.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 RUS85234.1 - 0.032 14.7 24.8 4.2 8.3 0.5 7.4 6 1 0 6 6 6 0 Leucine Rich Repeat DSPc PF00782.20 RUS85235.1 - 7.6e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS85235.1 - 5e-08 33.2 0.3 1.6e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 RUS85235.1 - 2.1e-07 30.8 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DDE_3 PF13358.6 RUS85235.1 - 2.3e-06 27.4 0.0 5.3e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Y_phosphatase3 PF13350.6 RUS85235.1 - 0.0054 16.7 0.1 0.0097 15.9 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Cytochrom_B561 PF03188.16 RUS85236.1 - 5.3e-09 36.3 6.5 5.3e-09 36.3 6.5 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Reeler PF02014.16 RUS85236.1 - 1.9e-07 31.9 0.0 2.1e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 Reeler domain DNA_pol_phi PF04931.13 RUS85236.1 - 0.015 13.4 28.0 0.021 13.0 28.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS85236.1 - 0.016 13.6 10.8 0.021 13.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS85236.1 - 0.02 13.2 14.8 0.026 12.8 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Orthoreo_P10 PF07204.11 RUS85236.1 - 0.083 12.9 0.2 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF2457 PF10446.9 RUS85236.1 - 0.3 10.2 34.6 0.46 9.6 34.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 RUS85236.1 - 0.37 9.3 16.0 0.53 8.8 16.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 RUS85236.1 - 0.65 9.3 10.3 0.97 8.8 10.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CNDH2_C PF16858.5 RUS85236.1 - 1.1 9.1 5.3 1.5 8.6 5.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Sigma70_ner PF04546.13 RUS85236.1 - 1.5 8.7 14.9 2.3 8.1 14.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 RUS85236.1 - 2.8 7.2 32.4 6.1 6.1 32.4 1.5 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.11 RUS85236.1 - 3.2 6.1 8.9 4.4 5.6 8.9 1.1 1 0 0 1 1 1 0 SGT1 protein Mpp10 PF04006.12 RUS85236.1 - 4.3 5.7 13.9 5.9 5.2 13.9 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 RUS85236.1 - 5.4 6.3 14.3 7.3 5.8 14.3 1.1 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 RUS85236.1 - 5.6 5.4 11.8 8.1 4.9 11.8 1.1 1 0 0 1 1 1 0 Utp14 protein eIF-3c_N PF05470.12 RUS85236.1 - 6.8 4.9 7.7 9.7 4.4 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FRQ PF09421.10 RUS85236.1 - 8 4.3 11.2 11 3.9 11.2 1.1 1 0 0 1 1 1 0 Frequency clock protein SDA1 PF05285.12 RUS85236.1 - 9.8 5.5 19.0 14 5.0 19.0 1.1 1 0 0 1 1 1 0 SDA1 Reeler PF02014.16 RUS85237.1 - 6e-18 65.8 0.0 1.1e-17 65.0 0.0 1.5 1 0 0 1 1 1 1 Reeler domain Trypsin_2 PF13365.6 RUS85238.1 - 0.01 16.7 0.0 0.026 15.4 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain RTT107_BRCT_5 PF16770.5 RUS85239.1 - 1.2e-13 50.7 0.0 3.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RUS85239.1 - 2.4e-07 31.0 0.0 7.4e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS85239.1 - 0.00018 21.8 0.0 0.0059 17.0 0.0 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 RUS85239.1 - 0.063 13.6 0.2 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Ag332 PF04671.12 RUS85240.1 - 0.066 13.1 0.3 0.21 11.5 0.3 1.9 1 0 0 1 1 1 0 Erythrocyte membrane-associated giant protein antigen 332 FHA PF00498.26 RUS85241.1 - 6.6e-09 36.0 0.1 1.2e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS85241.1 - 0.0087 16.4 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FKBP_C PF00254.28 RUS85242.1 - 2.2e-12 47.1 0.0 2.5e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AMP-binding PF00501.28 RUS85243.1 - 3.6e-45 154.3 0.0 4.4e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS85243.1 - 2.7e-10 41.1 0.6 1.9e-09 38.4 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 RUS85243.1 - 0.073 13.4 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RUS85244.1 - 4.2e-40 137.6 0.0 6.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS85244.1 - 1.1e-07 32.7 0.6 2.5e-07 31.6 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BON PF04972.17 RUS85244.1 - 0.085 13.2 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 BON domain CPSase_L_D2 PF02786.17 RUS85245.1 - 2.5e-112 373.5 0.1 8.9e-82 273.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 RUS85245.1 - 3.2e-52 175.7 0.0 6.3e-52 174.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RUS85245.1 - 2.3e-46 158.0 0.0 6e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 RUS85245.1 - 6.4e-44 149.5 0.0 1.2e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 RUS85245.1 - 5.9e-40 136.4 0.1 1.4e-39 135.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 RUS85245.1 - 5.6e-35 120.7 0.0 1.6e-34 119.3 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 RUS85245.1 - 9.2e-18 64.5 0.1 7.1e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RUS85245.1 - 8.1e-17 61.3 0.1 2.1e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 RUS85245.1 - 1.2e-16 60.7 0.0 4.7e-16 58.8 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 RUS85245.1 - 3.3e-11 43.1 0.2 9.4e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.20 RUS85245.1 - 2.4e-09 37.0 0.0 5.2e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family ATP-grasp_3 PF02655.14 RUS85245.1 - 4.2e-09 36.7 0.1 0.00025 21.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 RUS85245.1 - 2.9e-05 23.7 0.0 0.0061 16.2 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.13 RUS85245.1 - 6.9e-05 22.7 0.1 0.0018 18.1 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 RUS85245.1 - 0.0092 15.8 0.1 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DHOase PF12890.7 RUS85245.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Dihydro-orotase-like Ras PF00071.22 RUS85247.1 - 2.9e-17 62.8 0.0 8.1e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 RUS85247.1 - 3.2e-05 23.9 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS85247.1 - 0.00077 19.8 0.0 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 RUS85247.1 - 0.001 19.3 0.0 0.02 15.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RUS85247.1 - 0.0027 18.1 0.1 0.0093 16.4 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 RUS85247.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein G-alpha PF00503.20 RUS85247.1 - 0.0084 15.3 0.1 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 RUS85247.1 - 0.081 12.4 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Lig_chan-Glu_bd PF10613.9 RUS85248.1 - 1.6e-24 86.3 0.0 4.8e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 RUS85248.1 - 5.5e-20 71.7 0.7 1.1e-19 70.7 0.7 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS85248.1 - 1.9e-14 53.7 0.0 6e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phage_min_cap2 PF06152.11 RUS85248.1 - 0.059 12.3 0.3 0.087 11.7 0.3 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 ANF_receptor PF01094.28 RUS85248.1 - 0.17 11.0 0.6 0.32 10.0 0.6 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region Ank_5 PF13857.6 RUS85249.1 - 1.4e-20 73.1 2.7 1.6e-09 37.8 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS85249.1 - 1.1e-18 67.6 0.8 3e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS85249.1 - 6.7e-16 58.4 0.1 1.4e-11 44.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS85249.1 - 1.1e-14 53.1 0.3 0.0021 18.4 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 RUS85249.1 - 8.7e-14 51.3 2.2 0.00096 19.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat MgtE_N PF03448.17 RUS85249.1 - 0.025 15.2 5.0 0.062 13.9 5.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Cuticle_3 PF11018.8 RUS85249.1 - 0.46 10.7 5.3 0.062 13.5 0.6 1.9 2 0 0 2 2 2 0 Pupal cuticle protein C1 GAT PF03127.14 RUS85249.1 - 8.1 6.8 8.8 6.9 7.1 0.0 3.7 4 0 0 4 4 4 0 GAT domain CABIT PF12736.7 RUS85250.1 - 4.4e-10 39.3 0.0 6.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, DUF5561 PF17716.1 RUS85251.1 - 0.0073 15.6 0.1 0.0089 15.4 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5561) CdiI PF07262.11 RUS85251.1 - 0.049 13.4 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein ASCH PF04266.14 RUS85253.1 - 3e-18 66.4 0.0 3.5e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 ASCH domain adh_short_C2 PF13561.6 RUS85254.1 - 3e-51 174.2 0.0 4.3e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS85254.1 - 1.1e-49 168.6 0.1 1.3e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS85254.1 - 1.6e-11 44.5 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS85254.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RUS85254.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 RUS85254.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 RUS85254.1 - 0.025 14.0 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 RUS85254.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AdoHcyase_NAD PF00670.21 RUS85254.1 - 0.21 11.7 1.7 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 7tm_1 PF00001.21 RUS85255.1 - 9.8e-82 274.2 6.1 1.3e-81 273.8 6.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS85255.1 - 5.7e-11 42.3 15.1 1.5e-07 31.1 8.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS85255.1 - 0.00028 20.6 16.5 0.00028 20.6 16.5 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS85255.1 - 0.039 13.7 13.4 0.015 15.0 3.3 3.1 2 1 0 3 3 3 0 Olfactory receptor DUF1980 PF09323.10 RUS85255.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) DHHC PF01529.20 RUS85255.1 - 3.1 7.9 9.9 0.8 9.8 0.7 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Innate_immun PF12782.7 RUS85255.1 - 3.4 7.1 11.2 5 6.6 11.2 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Thioredoxin PF00085.20 RUS85256.1 - 8.6e-15 54.6 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 RUS85256.1 - 0.0095 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 RUS85256.1 - 0.041 14.3 0.2 0.66 10.5 0.2 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain KaiB PF07689.12 RUS85256.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiB domain Lectin_C PF00059.21 RUS85257.1 - 1.4e-16 61.1 0.5 2.8e-16 60.2 0.5 1.5 1 1 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 RUS85257.1 - 0.00055 19.3 0.1 0.0008 18.7 0.1 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Stealth_CR1 PF17101.5 RUS85257.1 - 0.28 10.9 1.2 0.54 10.0 1.2 1.4 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 Spc7 PF08317.11 RUS85258.1 - 0.045 12.6 0.1 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SRC-1 PF08832.10 RUS85258.1 - 0.33 12.0 4.3 4.7 8.4 1.1 2.5 2 0 0 2 2 2 0 Steroid receptor coactivator EF-hand_1 PF00036.32 RUS85259.1 - 5.6e-25 85.0 4.1 8.6e-08 31.2 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS85259.1 - 2.6e-23 82.2 0.7 4.4e-16 59.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS85259.1 - 1.4e-20 71.4 1.8 7.2e-07 28.6 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 RUS85259.1 - 7.9e-20 69.4 4.4 4.5e-06 25.9 0.2 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 RUS85259.1 - 4.2e-16 58.5 3.1 4.5e-05 23.2 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS85259.1 - 1.5e-05 25.3 0.3 0.022 15.1 0.1 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS85259.1 - 0.00092 19.1 0.6 1.4 8.9 0.0 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_3 PF09069.11 RUS85259.1 - 0.024 15.1 0.0 0.051 14.0 0.0 1.5 2 0 0 2 2 2 0 EF-hand Dockerin_1 PF00404.18 RUS85259.1 - 0.049 13.8 0.1 11 6.3 0.0 2.8 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_10 PF14788.6 RUS85259.1 - 0.049 13.5 0.5 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 EF hand Lectin_C PF00059.21 RUS85260.1 - 1.2e-65 219.0 12.4 5.1e-16 59.3 0.7 4.3 4 0 0 4 4 4 4 Lectin C-type domain Chordopox_A33R PF05966.12 RUS85260.1 - 7.6e-12 44.9 1.4 0.0047 16.2 0.0 4.4 4 0 0 4 4 4 4 Chordopoxvirus A33R protein DUF5075 PF16825.5 RUS85260.1 - 3.9e-07 29.9 0.1 1.8 8.2 0.0 5.6 5 0 0 5 5 5 2 IGP family C-type lectin domain UL45 PF05473.12 RUS85260.1 - 0.0036 17.0 0.0 20 4.8 0.0 4.1 4 0 0 4 4 4 2 UL45 protein, carbohydrate-binding C-type lectin-like Aspzincin_M35 PF14521.6 RUS85260.1 - 0.084 13.4 2.4 3.8 8.1 0.0 3.2 4 0 0 4 4 4 0 Lysine-specific metallo-endopeptidase DUF2709 PF10915.8 RUS85260.1 - 0.15 11.3 0.0 36 3.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2709) RhoGEF PF00621.20 RUS85261.1 - 2.1e-08 34.6 1.0 5.2e-08 33.3 0.0 2.2 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 RUS85261.1 - 0.00023 21.6 0.1 0.0016 18.9 0.0 2.5 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 RUS85262.1 - 2.4e-08 34.4 0.0 3.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain RTBV_P46 PF06216.11 RUS85262.1 - 0.011 14.6 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF908 PF06012.12 RUS85262.1 - 2.1 7.7 5.7 2.5 7.4 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HTH_48 PF17906.1 RUS85264.1 - 0.00057 19.9 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_32 PF13565.6 RUS85264.1 - 0.003 18.1 0.1 0.0036 17.9 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain DUF4817 PF16087.5 RUS85264.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) LRR_6 PF13516.6 RUS85265.1 - 1.5e-22 77.7 19.0 0.00061 19.6 0.0 8.6 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_7 PF13499.6 RUS85265.1 - 7.9e-09 35.9 1.4 7.9e-09 35.9 1.4 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS85265.1 - 2.9e-08 32.7 12.6 0.00018 20.8 0.3 3.2 3 0 0 3 3 2 2 EF hand EF-hand_6 PF13405.6 RUS85265.1 - 2.3e-06 27.1 8.7 0.0033 17.2 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain LRR_1 PF00560.33 RUS85265.1 - 2.7e-06 27.2 4.3 4.9 8.1 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat EF-hand_8 PF13833.6 RUS85265.1 - 4.1e-06 26.6 5.2 4.8e-06 26.3 0.3 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS85265.1 - 0.00017 21.0 8.0 0.042 13.3 1.1 2.8 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 RUS85265.1 - 0.01 15.6 13.3 1.4 8.8 2.7 4.9 3 2 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 RUS85265.1 - 0.01 16.2 15.1 0.58 10.7 2.0 5.1 3 3 3 6 6 6 0 Leucine Rich repeats (2 copies) EF-hand_11 PF08976.11 RUS85265.1 - 0.028 15.3 0.1 0.17 12.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Importin_rep_4 PF18808.1 RUS85265.1 - 0.076 13.3 0.2 0.26 11.6 0.2 1.9 1 0 0 1 1 1 0 Importin repeat LRR_2 PF07723.13 RUS85265.1 - 0.1 13.3 0.0 75 4.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat MarB PF13999.6 RUS85266.1 - 0.27 11.1 2.0 0.49 10.3 0.1 2.4 3 0 0 3 3 3 0 MarB protein Trypsin_2 PF13365.6 RUS85267.1 - 0.0023 18.8 0.0 0.0047 17.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain RVT_1 PF00078.27 RUS85268.1 - 1.4e-09 37.8 0.1 2.2e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_2 PF13646.6 RUS85269.1 - 3.9e-20 72.0 1.7 1.8e-11 44.3 0.7 2.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 RUS85269.1 - 2.2e-09 36.8 0.1 0.029 14.6 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat TIR_2 PF13676.6 RUS85269.1 - 2.8e-06 27.9 0.0 6.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain Cnd1 PF12717.7 RUS85269.1 - 4.8e-06 26.7 2.0 0.00015 21.8 0.0 3.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS85269.1 - 1.5e-05 25.4 0.7 0.13 12.8 0.1 3.1 3 0 0 3 3 3 2 HEAT-like repeat Cbl_N2 PF02761.14 RUS85269.1 - 0.0057 17.3 0.1 0.018 15.7 0.1 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Adaptin_N PF01602.20 RUS85269.1 - 0.0078 14.8 0.4 0.012 14.2 0.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 RUS85269.1 - 0.13 13.0 1.5 1.7e+02 3.3 0.1 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat LRR_6 PF13516.6 RUS85270.1 - 1.7e-22 77.5 14.2 0.011 15.7 0.0 8.9 8 0 0 8 8 8 5 Leucine Rich repeat EF-hand_1 PF00036.32 RUS85270.1 - 5.7e-10 38.0 2.2 0.00014 21.1 0.4 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS85270.1 - 1.4e-09 38.3 0.4 6.6e-09 36.1 0.4 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS85270.1 - 1.2e-07 31.5 0.2 3.4e-07 30.0 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS85270.1 - 8.4e-07 28.4 0.4 0.014 15.3 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain LRR_1 PF00560.33 RUS85270.1 - 3.2e-05 23.9 8.8 4.9 8.1 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat EF-hand_5 PF13202.6 RUS85270.1 - 3.7e-05 23.0 3.7 0.00068 19.0 0.5 2.7 2 0 0 2 2 2 1 EF hand LRR_4 PF12799.7 RUS85270.1 - 0.061 13.8 14.9 0.14 12.6 0.6 4.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS85270.1 - 0.076 12.8 14.7 0.031 14.1 1.7 4.4 4 1 0 4 4 4 0 Leucine rich repeat PAXX PF15384.6 RUS85271.1 - 2.1e-26 92.8 0.5 2.6e-26 92.5 0.5 1.1 1 0 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DASH_Dad2 PF08654.10 RUS85271.1 - 0.25 11.8 1.8 3.2 8.2 1.9 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 PPR_2 PF13041.6 RUS85272.1 - 2.2e-18 66.2 4.3 2.1e-07 31.0 0.2 7.8 7 1 3 10 10 10 4 PPR repeat family PPR_3 PF13812.6 RUS85272.1 - 2.8e-14 52.9 6.1 0.0001 22.3 0.1 6.1 5 1 3 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 RUS85272.1 - 6.3e-14 51.2 10.3 0.0029 17.7 0.0 9.6 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.7 RUS85272.1 - 1.1e-10 41.1 7.7 1.4e-07 31.1 0.0 5.9 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 RUS85272.1 - 4.3e-08 32.8 0.0 2.4e-05 23.8 0.0 3.3 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 RUS85272.1 - 0.0056 17.1 0.6 0.04 14.3 0.5 2.5 1 1 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF724 PF05266.14 RUS85272.1 - 0.029 14.2 0.4 0.068 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2288 PF10052.9 RUS85272.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) TPR_8 PF13181.6 RUS85272.1 - 0.43 10.9 2.6 29 5.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BCMA-Tall_bind PF09257.10 RUS85272.1 - 1 9.5 2.9 0.5 10.5 0.2 1.9 2 0 0 2 2 2 0 BCMA, TALL-1 binding DUF2052 PF09747.9 RUS85273.1 - 8.4e-42 143.6 28.8 8.4e-42 143.6 28.8 2.6 2 2 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) LRR_4 PF12799.7 RUS85275.1 - 1.6e-12 47.4 12.2 2.3e-06 27.8 2.7 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS85275.1 - 2.8e-08 33.5 0.5 0.00014 21.5 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 RUS85275.1 - 0.00014 21.6 11.0 0.011 15.5 3.2 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 RUS85275.1 - 0.56 10.4 4.2 7.6 6.9 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 RUS85275.1 - 1.6 9.5 6.1 84 4.3 0.2 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat SAS4 PF15460.6 RUS85276.1 - 0.003 17.6 4.4 0.003 17.6 4.4 2.4 1 1 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 DUF948 PF06103.11 RUS85276.1 - 0.36 11.1 3.3 0.64 10.3 0.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 RUS85276.1 - 0.71 10.1 18.2 1.2 9.3 4.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family T2SSF PF00482.23 RUS85276.1 - 0.91 9.5 5.6 10 6.1 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-U11-48K PF05253.12 RUS85277.1 - 0.00014 21.7 4.7 0.00036 20.4 4.7 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger CENP-K PF11802.8 RUS85278.1 - 4.9e-30 105.0 14.4 5.4e-30 104.8 14.4 1.0 1 0 0 1 1 1 1 Centromere-associated protein K MSC PF09402.10 RUS85278.1 - 0.027 13.9 2.6 0.036 13.5 2.6 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain FCD PF07729.12 RUS85278.1 - 0.23 11.9 3.1 2.8 8.4 0.2 2.8 1 1 1 2 2 2 0 FCD domain Atg14 PF10186.9 RUS85278.1 - 0.5 9.4 7.7 0.66 9.0 7.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CpxA_peri PF16527.5 RUS85278.1 - 0.79 10.1 5.0 0.34 11.3 2.0 1.9 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain DUF4164 PF13747.6 RUS85278.1 - 0.95 9.8 14.8 0.23 11.8 5.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF5345 PF17280.2 RUS85278.1 - 1.3 9.1 8.3 0.78 9.7 0.8 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5345) Flagellin_N PF00669.20 RUS85278.1 - 1.3 9.1 5.4 1.7 8.8 3.8 1.9 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Dpy-30 PF05186.13 RUS85279.1 - 5.8e-20 70.7 0.5 2.6e-19 68.6 0.3 2.1 2 0 0 2 2 2 1 Dpy-30 motif ADK PF00406.22 RUS85279.1 - 3.6e-15 56.4 0.5 4e-11 43.2 0.5 3.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RUS85279.1 - 6.2e-07 29.9 8.5 6e-06 26.7 0.1 3.8 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 RUS85279.1 - 4.4e-06 27.3 0.1 4.4e-06 27.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS85279.1 - 0.00058 20.0 0.0 0.00058 20.0 0.0 2.2 3 0 0 3 3 1 1 AAA domain KTI12 PF08433.10 RUS85279.1 - 0.002 17.6 0.0 0.0052 16.3 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 RUS85279.1 - 0.0026 18.2 3.6 0.014 15.8 0.4 3.7 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS85279.1 - 0.0035 17.6 0.1 0.49 10.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RUS85279.1 - 0.0037 17.7 0.0 0.0037 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 RUS85279.1 - 0.01 16.1 0.3 0.01 16.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RUS85279.1 - 0.02 14.9 0.7 0.075 13.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RUS85279.1 - 0.024 14.6 0.0 0.024 14.6 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 RUS85279.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain RITA PF17066.5 RUS85279.1 - 0.062 12.9 0.5 0.15 11.6 0.5 1.6 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein DUF3095 PF11294.8 RUS85279.1 - 0.13 11.3 1.5 0.31 10.1 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) ABC_tran PF00005.27 RUS85279.1 - 0.22 12.1 0.8 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.20 RUS85279.1 - 0.34 10.0 5.9 0.32 10.1 4.2 1.8 1 1 0 1 1 1 0 G-protein alpha subunit Hydin_ADK PF17213.3 RUS85279.1 - 0.59 10.4 4.9 0.42 10.9 0.1 2.7 1 1 1 3 3 3 0 Hydin Adenylate kinase-like domain Caldesmon PF02029.15 RUS85279.1 - 2.4 6.9 32.0 0.37 9.5 27.1 1.9 2 0 0 2 2 2 0 Caldesmon DUF3987 PF13148.6 RUS85279.1 - 3.6 6.5 15.0 0.022 13.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ATP-synt_DE_N PF02823.16 RUS85280.1 - 3.4e-18 65.3 0.0 4.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Collagen_mid PF15984.5 RUS85281.1 - 0.00051 19.9 16.7 0.082 12.7 9.0 3.0 1 1 1 2 2 2 2 Bacterial collagen, middle region DUF3659 PF12396.8 RUS85281.1 - 0.0031 17.4 12.2 14 5.7 12.0 3.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3659) DUF3764 PF12594.8 RUS85281.1 - 0.2 11.8 12.1 37 4.5 0.1 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF3764) Seadorna_Vp10 PF07322.11 RUS85281.1 - 0.79 9.1 4.7 17 4.7 0.5 3.0 1 1 1 3 3 3 0 Seadornavirus Vp10 DUF5380 PF17351.2 RUS85281.1 - 1 9.3 7.1 48 3.9 0.1 5.0 1 1 2 5 5 5 0 Family of unknown function (DUF5380) DUF2099 PF09872.9 RUS85281.1 - 2.5 7.2 12.8 8.4 5.5 0.8 3.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2099) OMS28_porin PF03532.13 RUS85281.1 - 2.7 7.2 6.7 12 5.0 2.2 2.6 1 1 1 2 2 2 0 OMS28 porin Rossmann-like PF10727.9 RUS85281.1 - 3.2 7.6 14.6 1.1 9.1 0.3 3.2 1 1 2 3 3 3 0 Rossmann-like domain Collagen_mid PF15984.5 RUS85282.1 - 0.0036 17.1 103.4 0.34 10.6 8.3 8.6 1 1 4 5 5 5 3 Bacterial collagen, middle region DUF3764 PF12594.8 RUS85282.1 - 0.28 11.3 0.6 26 5.0 0.0 4.5 2 1 1 4 4 4 0 Protein of unknown function (DUF3764) BTB PF00651.31 RUS85283.1 - 1.8e-22 79.6 4.2 9e-19 67.8 0.3 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 RUS85283.1 - 7.2e-16 58.2 0.1 3.6e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS85283.1 - 0.034 14.4 0.2 3.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Kelch motif CCD48 PF15799.5 RUS85283.1 - 0.24 9.7 0.0 0.34 9.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Cadherin PF00028.17 RUS85284.1 - 6.3e-08 33.0 0.0 3.8e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 Cadherin domain Cadherin PF00028.17 RUS85285.1 - 1.1e-14 54.6 3.7 2.3e-06 27.9 0.1 3.0 3 0 0 3 3 3 2 Cadherin domain TMEM154 PF15102.6 RUS85285.1 - 0.00048 20.1 0.1 0.0017 18.3 0.1 2.0 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 RUS85285.1 - 0.0005 19.8 2.2 0.00097 18.8 2.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 RUS85285.1 - 0.0028 18.5 0.0 0.0055 17.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SID-1_RNA_chan PF13965.6 RUS85285.1 - 0.0051 15.3 0.1 0.0071 14.8 0.1 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Protocadherin PF08374.11 RUS85285.1 - 0.017 15.1 1.6 0.025 14.5 0.3 1.8 1 1 0 1 1 1 0 Protocadherin Glycophorin_A PF01102.18 RUS85285.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A Herpes_gE PF02480.16 RUS85285.1 - 0.028 13.2 0.0 0.058 12.1 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 RUS85285.1 - 0.045 13.6 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Rifin Cadherin_3 PF16184.5 RUS85285.1 - 0.049 13.6 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 Cadherin-like DUF5527 PF17665.1 RUS85285.1 - 0.059 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DAP10 PF07213.11 RUS85285.1 - 0.098 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Orf78 PF06024.12 RUS85285.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 Orf78 (ac78) Cadherin_C_2 PF16492.5 RUS85285.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MAP17 PF15807.5 RUS85285.1 - 0.16 12.2 0.2 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TRP PF06011.12 RUS85285.1 - 0.24 10.1 0.1 0.43 9.3 0.1 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF4383 PF14325.6 RUS85286.1 - 0.16 12.3 6.9 0.18 12.1 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4383) 7TM_GPCR_Srx PF10328.9 RUS85286.1 - 0.32 10.6 19.4 0.5 10.0 19.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx APG6_N PF17675.1 RUS85287.1 - 0.0042 17.6 8.5 0.0042 17.6 8.5 9.9 1 1 9 10 10 10 3 Apg6 coiled-coil region PH PF00169.29 RUS85288.1 - 2.8e-11 43.9 0.1 4.9e-11 43.1 0.1 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS85288.1 - 0.00075 19.9 0.2 0.0022 18.4 0.2 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 RUS85288.1 - 0.015 15.5 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2367 PF10164.9 RUS85288.1 - 0.057 13.9 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) TPR_1 PF00515.28 RUS85290.1 - 2.8e-07 30.1 0.1 0.0057 16.4 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS85290.1 - 2.9e-06 27.0 0.1 0.026 14.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS85290.1 - 2.5e-05 24.6 0.8 0.014 16.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS85290.1 - 5.3e-05 23.8 0.2 0.26 12.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85290.1 - 0.00013 21.9 0.1 0.01 16.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS85290.1 - 0.0004 20.8 0.2 0.0076 16.7 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85290.1 - 0.04 14.2 0.4 10 6.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 RUS85290.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 RUS85290.1 - 0.086 13.7 0.4 2.1 9.4 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS85290.1 - 0.11 12.6 0.2 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 RUS85291.1 - 5.2e-33 114.8 0.6 1.2e-32 113.7 0.6 1.6 1 0 0 1 1 1 1 RhoGEF domain betaPIX_CC PF16523.5 RUS85291.1 - 1.1e-16 60.5 3.1 1.1e-16 60.5 3.1 1.9 2 0 0 2 2 2 1 betaPIX coiled coil SH3_9 PF14604.6 RUS85291.1 - 2.7e-15 56.0 0.1 4.9e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS85291.1 - 1.2e-14 53.7 0.2 2.6e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS85291.1 - 2.5e-14 52.6 0.1 8.3e-14 50.9 0.1 2.0 1 0 0 1 1 1 1 SH3 domain RhoGEF67_u2 PF16614.5 RUS85291.1 - 5.3e-14 52.2 0.1 2.4e-13 50.1 0.1 2.2 1 0 0 1 1 1 1 Unstructured region two on RhoGEF 6 and 7 PH PF00169.29 RUS85291.1 - 0.00055 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 PH domain CCDC144C PF14915.6 RUS85291.1 - 0.004 16.3 2.5 0.0084 15.3 2.5 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CortBP2 PF09727.9 RUS85291.1 - 0.38 10.6 7.9 0.65 9.9 3.3 3.1 3 0 0 3 3 3 0 Cortactin-binding protein-2 DUF4498 PF14926.6 RUS85292.1 - 1.2e-91 306.4 3.7 1.4e-91 306.2 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) ATLF PF07737.11 RUS85292.1 - 0.059 12.7 0.6 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain HEAT PF02985.22 RUS85294.1 - 1.5e-12 46.6 4.7 0.42 11.0 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 RUS85294.1 - 6.2e-09 36.1 0.0 0.017 15.5 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 RUS85294.1 - 3e-07 29.4 2.2 0.019 13.6 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 RUS85294.1 - 0.00072 19.6 4.6 0.37 10.8 0.2 4.3 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RUS85294.1 - 0.0071 16.9 0.8 23 5.7 0.0 3.8 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 RUS85294.1 - 0.057 13.0 0.2 1.2 8.7 0.0 3.1 3 2 1 4 4 4 0 CLASP N terminal Ras PF00071.22 RUS85295.1 - 3e-56 189.5 0.1 3.4e-56 189.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85295.1 - 8.1e-21 74.5 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85295.1 - 1.2e-08 34.6 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS85295.1 - 0.00021 21.2 0.0 0.64 9.9 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS85295.1 - 0.0011 19.0 0.1 0.0018 18.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS85295.1 - 0.015 14.9 0.6 0.097 12.2 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RUS85295.1 - 0.12 11.9 0.1 0.41 10.2 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4205 PF13898.6 RUS85296.1 - 6.1e-102 341.1 0.0 7.1e-102 340.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) SMN PF06003.12 RUS85296.1 - 0.082 12.2 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ion_trans PF00520.31 RUS85297.1 - 6.7e-31 107.4 16.8 1.3e-30 106.4 16.8 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS85297.1 - 1.4e-11 44.2 10.6 1.4e-11 44.2 10.6 2.1 2 0 0 2 2 2 1 Ion channel SRTM1 PF15872.5 RUS85297.1 - 0.1 12.8 1.4 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 WD40 PF00400.32 RUS85299.1 - 1.5e-24 85.7 6.4 0.00031 21.5 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85299.1 - 0.00011 22.4 0.0 5.7 7.3 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L2_C PF03947.18 RUS85301.1 - 3.5e-47 159.7 4.7 5.8e-47 159.0 4.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RUS85301.1 - 2.4e-16 59.5 0.2 1e-15 57.4 0.2 2.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Sybindin PF04099.12 RUS85302.1 - 2.6e-43 147.4 1.3 2.9e-43 147.2 1.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RUS85302.1 - 1.3e-06 28.6 0.5 1.5e-06 28.4 0.5 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Cupin_8 PF13621.6 RUS85303.1 - 9.9e-23 81.2 0.0 1.5e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 RUS85303.1 - 8.6e-11 42.3 0.0 2.3e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 RUS85303.1 - 0.0091 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Rotamase_3 PF13616.6 RUS85304.1 - 1.6e-19 70.6 0.0 3.2e-19 69.6 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 RUS85304.1 - 4.6e-15 56.3 0.0 8.9e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RUS85304.1 - 0.012 16.5 0.0 0.02 15.7 0.0 1.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain Lamp PF01299.17 RUS85305.1 - 4.4e-12 46.1 4.2 5.9e-11 42.4 0.3 2.4 2 1 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 RUS85305.1 - 0.00018 21.4 0.3 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) CTV_P6 PF06706.11 RUS85305.1 - 0.076 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DUF5383 PF17355.2 RUS85305.1 - 0.081 13.3 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Rax2 PF12768.7 RUS85305.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VWA PF00092.28 RUS85306.1 - 1.9e-05 25.0 0.0 4.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain MAP17 PF15807.5 RUS85306.1 - 5.1 7.3 7.7 0.29 11.4 1.0 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 zf-CCHC_5 PF14787.6 RUS85307.1 - 9.3 6.1 19.3 0.86 9.4 8.7 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.25 RUS85308.1 - 5.4e-46 157.1 0.0 5.9e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85308.1 - 4.9e-24 85.0 0.0 6.1e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS85308.1 - 2.6e-06 27.0 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS85308.1 - 0.00081 18.4 0.1 0.001 18.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS85308.1 - 0.0094 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RUS85308.1 - 0.01 14.9 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RUS85308.1 - 0.025 13.9 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS85308.1 - 0.066 12.0 0.1 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RUS85308.1 - 0.21 11.2 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 RUS85308.1 - 0.26 10.2 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-MIZ PF02891.20 RUS85309.1 - 1.4e-22 79.2 4.8 1.4e-22 79.2 4.8 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 RUS85309.1 - 6.5e-05 22.7 1.7 6.5e-05 22.7 1.7 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit ASFV_J13L PF05568.11 RUS85310.1 - 0.93 9.2 10.1 1.1 9.0 10.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein RT_RNaseH_2 PF17919.1 RUS85311.1 - 5e-34 116.3 0.0 8.2e-34 115.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS85311.1 - 1.8e-33 115.0 0.0 2.9e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RUS85311.1 - 8.2e-13 48.3 0.1 1.5e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 RUS85311.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS85311.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Zmiz1_N PF18028.1 RUS85312.1 - 1.5e-33 115.0 0.1 1.9e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain MSG PF02349.15 RUS85313.1 - 0.14 12.3 0.4 0.36 11.1 0.4 1.6 1 0 0 1 1 1 0 Major surface glycoprotein Ras PF00071.22 RUS85314.1 - 6e-53 178.8 0.3 8.1e-53 178.3 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85314.1 - 1.7e-33 115.4 0.1 2.8e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85314.1 - 7.6e-18 64.6 0.2 9.7e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS85314.1 - 4.3e-09 36.1 0.1 6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS85314.1 - 4e-08 33.3 0.0 8.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS85314.1 - 6.8e-08 32.3 1.2 7.4e-06 25.6 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 RUS85314.1 - 1.4e-07 31.0 1.4 4.3e-06 26.1 0.5 2.4 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 RUS85314.1 - 4.4e-06 26.2 0.0 9.8e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TniB PF05621.11 RUS85314.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 RUS85314.1 - 0.021 14.8 0.0 2.9 7.8 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 RUS85314.1 - 0.033 13.9 0.1 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CTD_bind PF04818.13 RUS85316.1 - 1.5e-06 28.9 0.0 5.5e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. UQ_con PF00179.26 RUS85317.1 - 5.5e-53 178.4 0.0 6.4e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS85317.1 - 0.0012 19.1 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 RUS85317.1 - 0.056 13.1 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 RUS85317.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain Corona_nucleoca PF00937.18 RUS85318.1 - 1.3 8.0 34.6 0.055 12.5 12.0 2.2 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein GREB1 PF15782.5 RUS85318.1 - 3.6 4.6 13.2 4.6 4.2 13.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RVT_1 PF00078.27 RUS85319.1 - 8.2e-50 169.4 0.1 1.5e-49 168.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS85319.1 - 6.1e-18 64.8 0.5 3.7e-17 62.3 0.5 2.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS85319.1 - 7.1e-15 55.2 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 RUS85319.1 - 3.1e-06 27.4 0.0 3.1e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 RNase H Usp PF00582.26 RUS85320.1 - 9e-25 87.8 0.0 1.1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family SR-25 PF10500.9 RUS85321.1 - 6.3e-05 22.7 21.9 0.00013 21.7 21.9 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Eapp_C PF10238.9 RUS85321.1 - 0.00069 19.7 4.9 0.00094 19.3 4.9 1.4 1 0 0 1 1 1 1 E2F-associated phosphoprotein AP3D1 PF06375.11 RUS85321.1 - 0.0023 18.2 16.5 0.0036 17.6 16.5 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Med19 PF10278.9 RUS85321.1 - 0.087 12.8 19.5 0.13 12.2 19.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FAM91_C PF14648.6 RUS85321.1 - 0.18 10.6 2.1 0.19 10.6 2.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus EFTUD2 PF16004.5 RUS85321.1 - 0.21 12.2 5.8 0.058 14.0 2.4 1.7 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF2201_N PF13203.6 RUS85321.1 - 0.4 10.3 4.7 0.6 9.7 4.4 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain PH_4 PF15404.6 RUS85321.1 - 0.46 10.2 9.2 0.69 9.7 9.2 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain EOS1 PF12326.8 RUS85321.1 - 0.48 10.3 3.2 0.71 9.8 3.2 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF4604 PF15377.6 RUS85321.1 - 3.9 7.9 23.8 3.2 8.1 22.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Presenilin PF01080.17 RUS85321.1 - 6.9 5.3 8.6 8.4 5.0 8.6 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 RUS85321.1 - 8 5.2 7.1 9.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Alk_phosphatase PF00245.20 RUS85322.1 - 2.1e-122 409.1 0.2 2.4e-122 408.9 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS85322.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 RUS85323.1 - 1.1e-106 357.2 0.1 1.3e-106 357.0 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS85323.1 - 0.0049 16.3 0.0 0.0058 16.0 0.0 1.3 1 1 0 1 1 1 1 Metalloenzyme superfamily 3-alpha PF03475.14 RUS85324.1 - 0.00015 21.5 0.5 71 3.4 0.0 5.9 4 3 5 9 9 9 0 3-alpha domain DUF4217 PF13959.6 RUS85324.1 - 1.5 9.1 8.8 62 3.9 0.1 5.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4217) SWIB PF02201.18 RUS85324.1 - 2.1 8.3 5.1 1.7e+02 2.2 0.0 4.3 4 3 2 6 6 6 0 SWIB/MDM2 domain RCC1 PF00415.18 RUS85325.1 - 7.7e-59 196.1 19.3 4.8e-16 59.1 0.0 7.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS85325.1 - 1.8e-31 107.3 17.6 2.5e-10 39.8 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 RUS85325.1 - 0.00026 21.5 0.1 0.7 10.4 0.0 4.0 4 0 0 4 4 4 1 SUKH-3 immunity protein Kelch_2 PF07646.15 RUS85325.1 - 0.25 11.4 1.6 1.5 8.9 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Holin_9 PF16936.5 RUS85327.1 - 0.45 10.7 4.7 18 5.6 0.1 3.7 1 1 4 5 5 5 0 Putative holin DUF166 PF02593.14 RUS85327.1 - 0.93 9.0 9.8 15 5.0 0.3 3.8 1 1 1 3 3 3 0 Domain of unknown function GST_N_4 PF17172.4 RUS85328.1 - 4.4e-26 91.5 0.2 1.3e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS85328.1 - 1.4e-13 50.4 0.1 2.7e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS85328.1 - 4.6e-07 29.8 0.1 7.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RUS85328.1 - 2.7e-05 24.5 0.0 7.1e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 RUS85328.1 - 0.0035 17.5 0.0 0.0073 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS85328.1 - 0.0036 17.5 0.6 0.072 13.3 0.5 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SMC_ScpB PF04079.16 RUS85329.1 - 6.5e-08 32.4 0.1 2.5 7.7 0.0 4.8 1 1 2 5 5 5 3 Segregation and condensation complex subunit ScpB CoA_binding PF02629.19 RUS85329.1 - 1.8e-06 28.6 0.0 8.4 7.2 0.0 5.3 2 1 2 5 5 5 1 CoA binding domain DUF5440 PF17509.2 RUS85329.1 - 0.00032 20.2 1.8 38 4.0 0.0 5.0 1 1 2 5 5 5 0 Family of unknown function (DUF5440) XPG_N PF00752.17 RUS85329.1 - 0.011 16.2 0.8 22 5.6 0.1 5.0 1 1 4 6 6 6 0 XPG N-terminal domain Zwilch PF09817.9 RUS85329.1 - 0.096 11.1 0.2 9.7 4.5 0.0 2.7 1 1 1 2 2 2 0 RZZ complex, subunit zwilch Spindle_Spc25 PF08234.12 RUS85329.1 - 0.28 11.4 8.8 37 4.6 0.0 6.0 1 1 7 10 10 10 0 Chromosome segregation protein Spc25 Glyco_transf_52 PF07922.11 RUS85329.1 - 0.88 8.8 4.1 3.3 6.9 0.1 3.2 1 1 3 4 4 4 0 Glycosyltransferase family 52 Mre11_DNA_bind PF04152.14 RUS85329.1 - 6.8 7.0 15.4 2.5e+02 1.9 0.1 6.1 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain RFX_DNA_binding PF02257.15 RUS85331.1 - 6.6e-21 74.7 0.0 8.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 RUS85331.1 - 0.0023 18.4 0.0 0.0033 17.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus D5 protein-like EH_Signature PF15611.6 RUS85331.1 - 0.021 14.3 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 EH_Signature domain RFX5_N PF18326.1 RUS85331.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 RFX5 N-terminal domain FAS_I_H PF18314.1 RUS85331.1 - 0.079 12.6 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Pkinase_Tyr PF07714.17 RUS85333.1 - 1.4e-64 217.9 0.0 2.1e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS85333.1 - 7.6e-59 199.2 0.0 1.5e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 RUS85333.1 - 8.4e-12 44.5 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS85333.1 - 1.1e-10 41.0 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS85333.1 - 1.4e-10 40.8 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_fungal PF17667.1 RUS85333.1 - 0.0016 17.3 0.5 0.0039 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF3552 PF12072.8 RUS85333.1 - 0.046 13.1 8.8 0.08 12.4 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APH PF01636.23 RUS85333.1 - 0.48 10.3 2.2 0.73 9.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lectin_C PF00059.21 RUS85335.1 - 3.3e-14 53.5 0.0 4.6e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS85337.1 - 2.3e-06 28.3 0.1 5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 RUS85337.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein LBP_BPI_CETP PF01273.25 RUS85338.1 - 5.4e-24 84.6 0.0 7.1e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 RUS85338.1 - 0.0044 16.2 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) Proteasome PF00227.26 RUS85339.1 - 2.9e-50 170.4 0.2 3.7e-50 170.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 RUS85339.1 - 1.5e-09 37.1 0.2 1.5e-09 37.1 0.2 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Hemopexin PF00045.19 RUS85340.1 - 3.6e-25 87.6 0.4 0.012 15.5 0.0 8.8 8 0 0 8 8 8 7 Hemopexin Antimicrobial_8 PF08103.11 RUS85341.1 - 0.05 13.8 1.0 63 4.0 0.1 5.1 2 0 0 2 2 2 0 Uperin family CBM_14 PF01607.24 RUS85342.1 - 3.1e-15 56.1 20.4 2.6e-12 46.7 9.0 2.9 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain 7tm_1 PF00001.21 RUS85343.1 - 4.2e-52 177.1 14.4 5.3e-52 176.7 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS85343.1 - 2.2e-14 53.5 4.2 3.3e-14 52.9 4.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS85343.1 - 6.4e-06 26.1 4.6 6.4e-06 26.1 4.6 1.8 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 RUS85343.1 - 0.036 13.3 15.2 0.55 9.5 0.1 3.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw EF-hand_1 PF00036.32 RUS85344.1 - 2.6e-08 32.8 7.7 0.00054 19.3 0.1 3.8 2 2 2 4 4 4 2 EF hand EF-hand_5 PF13202.6 RUS85344.1 - 5.1e-08 32.1 4.6 0.0014 18.0 0.3 3.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RUS85344.1 - 7.5e-08 31.7 10.6 0.075 13.0 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 RUS85344.1 - 3.5e-06 27.4 8.0 2.3e-05 24.8 6.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS85344.1 - 3.6e-06 26.7 9.3 0.00062 19.6 0.4 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS85345.1 - 2.2e-05 23.7 5.8 0.00023 20.5 0.4 3.1 2 2 1 3 3 3 1 EF hand EF-hand_5 PF13202.6 RUS85345.1 - 0.00016 21.0 1.9 0.0025 17.3 0.5 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS85345.1 - 0.00028 20.6 7.1 0.0027 17.5 0.4 3.2 2 2 2 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RUS85345.1 - 0.0019 18.6 3.5 0.0038 17.6 3.2 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS85345.1 - 0.0032 17.3 7.1 0.11 12.3 0.6 2.8 2 1 1 3 3 3 2 EF-hand domain pair UPF0449 PF15136.6 RUS85346.1 - 4.5e-14 52.7 0.1 7.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DENN PF02141.21 RUS85347.1 - 1.9e-41 142.1 0.0 3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 RUS85347.1 - 2.5e-07 30.6 0.8 6.1e-07 29.3 0.8 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 RUS85347.1 - 0.00039 21.1 1.0 0.00094 19.9 1.0 1.7 1 0 0 1 1 1 1 uDENN domain AMP-binding PF00501.28 RUS85349.1 - 1e-70 238.5 0.0 1.3e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS85349.1 - 5.9e-05 24.0 0.0 0.00012 23.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 RUS85350.1 - 2.2e-06 28.2 0.0 3.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS85350.1 - 0.0013 19.1 0.0 0.058 14.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RUS85350.1 - 0.0028 18.0 0.2 0.0053 17.1 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 RUS85350.1 - 0.0052 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS85350.1 - 0.0057 17.2 0.0 0.0086 16.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Proteasome PF00227.26 RUS85351.1 - 1.5e-32 112.6 0.0 1.8e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Acetyltransf_2 PF00797.17 RUS85352.1 - 5e-07 29.7 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase Tox-REase-7 PF15649.6 RUS85352.1 - 0.05 13.9 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 TRAF_BIRC3_bd PF16673.5 RUS85354.1 - 3.1e-06 26.9 0.1 5.1e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 RUS85355.1 - 2.6e-18 66.5 26.2 2.5e-07 31.3 4.4 3.1 1 1 2 3 3 3 3 TRAF-type zinc finger zf-ACC PF17848.1 RUS85355.1 - 6.7e-07 29.3 5.8 0.017 15.2 0.7 3.8 3 0 0 3 3 3 2 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 RUS85355.1 - 1.5e-06 27.7 15.1 0.013 15.1 0.1 4.5 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-RAG1 PF10426.9 RUS85355.1 - 0.0023 18.0 0.1 0.011 15.8 0.1 2.3 1 0 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain Sgf11 PF08209.11 RUS85355.1 - 0.017 14.6 8.2 5.3 6.7 0.0 4.2 3 1 1 4 4 4 0 Sgf11 (transcriptional regulation protein) PRP21_like_P PF12230.8 RUS85355.1 - 0.086 12.7 5.0 0.091 12.6 0.3 2.4 2 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein DegT_DnrJ_EryC1 PF01041.17 RUS85355.1 - 0.15 11.3 0.3 0.17 11.2 0.3 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rhodanese_C PF12368.8 RUS85355.1 - 0.28 11.6 20.3 0.31 11.5 9.9 2.3 1 1 1 2 2 2 0 Rhodanase C-terminal zf-Sec23_Sec24 PF04810.15 RUS85355.1 - 1.2 9.3 11.4 5.7 7.1 0.2 4.3 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger zf-C3HC PF07967.13 RUS85355.1 - 2.3 8.2 15.1 1.4 9.0 12.8 1.7 1 1 1 2 2 2 0 C3HC zinc finger-like DZR PF12773.7 RUS85355.1 - 4.6 7.3 17.3 4e+02 1.1 17.3 2.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 RUS85355.1 - 4.8 7.8 10.4 3.1 8.4 4.4 2.7 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain GTP_EFTU PF00009.27 RUS85356.1 - 6.6e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 RUS85356.1 - 7e-39 133.2 15.7 1.3e-38 132.3 15.7 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 RUS85356.1 - 9.8e-26 89.9 0.0 2.4e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 RUS85356.1 - 2e-21 75.8 0.0 4.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RUS85356.1 - 6.4e-12 45.7 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RUS85356.1 - 3.6e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 RUS85356.1 - 0.046 13.9 0.0 3 8.1 0.0 3.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Nop14 PF04147.12 RUS85356.1 - 2.4 6.3 8.0 3.4 5.7 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS85356.1 - 2.4 7.4 5.2 3.8 6.7 5.2 1.2 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 RUS85356.1 - 6.5 7.2 18.4 15 6.1 18.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 RUS85356.1 - 7 6.7 10.3 11 6.0 10.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein MID_pPIWI_RE PF18157.1 RUS85357.1 - 0.02 15.2 1.6 0.02 15.2 1.6 2.3 2 1 1 3 3 3 0 MID domain of pPIWI_RE DivIC PF04977.15 RUS85357.1 - 2.7 7.8 6.0 0.71 9.7 0.7 2.5 3 0 0 3 3 3 0 Septum formation initiator Nucleos_tra2_N PF01773.20 RUS85358.1 - 1.7e-21 76.6 3.8 1.7e-21 76.6 3.8 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus TPPK_C PF12555.8 RUS85358.1 - 0.054 13.5 0.6 8.9 6.4 0.1 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Nucleos_tra2_C PF07662.13 RUS85359.1 - 3.6e-41 141.3 3.8 4e-41 141.2 3.8 1.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Sulfotransfer_1 PF00685.27 RUS85360.1 - 1.3e-14 54.3 0.0 8.6e-14 51.6 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85360.1 - 9.1e-14 52.4 0.3 2.5e-09 37.8 0.5 2.9 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS85360.1 - 0.013 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_4 PF17784.1 RUS85360.1 - 0.014 15.2 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Nucleos_tra2_C PF07662.13 RUS85361.1 - 1.9e-51 174.9 1.3 1.9e-51 174.9 1.3 2.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS85361.1 - 5.7e-25 87.7 6.3 1.3e-24 86.5 1.8 3.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 RUS85361.1 - 2.4e-10 40.7 5.5 2.4e-10 40.7 5.5 3.6 3 1 2 5 5 5 1 Nucleoside recognition DUF3290 PF11694.8 RUS85361.1 - 0.023 14.7 0.5 6.7 6.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) TMEM141 PF15110.6 RUS85361.1 - 0.03 14.9 0.1 1.4 9.5 0.0 2.7 2 0 0 2 2 2 0 TMEM141 protein family Molybdopterin PF00384.22 RUS85363.1 - 1.3e-63 215.4 0.0 8e-62 209.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 RUS85363.1 - 4.6e-20 71.4 0.4 1e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 RUS85363.1 - 1.9e-16 59.3 0.1 4.6e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 RUS85363.1 - 1.4e-12 48.1 0.2 3.5e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 RUS85363.1 - 3.6e-09 36.5 0.5 3.6e-09 36.5 0.5 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 RUS85363.1 - 0.0098 15.6 0.1 1.1 8.9 0.0 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Abhydrolase_1 PF00561.20 RUS85364.1 - 3.3e-23 82.6 0.2 6.3e-22 78.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS85364.1 - 1.9e-15 58.1 0.0 2.7e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS85364.1 - 9.8e-09 34.8 0.0 2.4e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS85365.1 - 5.3e-24 85.2 0.1 7e-21 75.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS85365.1 - 4.9e-16 60.0 0.0 5.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS85365.1 - 4.1e-08 32.8 0.0 8e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 RUS85365.1 - 0.018 15.4 0.0 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DSPc PF00782.20 RUS85366.1 - 4.7e-30 104.1 0.0 7e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS85366.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RUS85366.1 - 0.0056 17.0 0.0 0.0087 16.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Bee_toxin PF17454.2 RUS85368.1 - 6.9 6.8 8.4 0.62 10.1 2.9 2.1 2 1 1 3 3 3 0 Honey bee toxin SUZ PF12752.7 RUS85369.1 - 9.1e-10 39.2 1.2 9.1e-10 39.2 1.2 3.0 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 RUS85369.1 - 4.2e-07 29.9 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain IgGFc_binding PF17517.2 RUS85370.1 - 7.3e-21 74.7 3.6 1e-08 34.9 0.1 3.8 3 1 1 4 4 4 3 IgGFc binding protein M-factor PF03855.13 RUS85370.1 - 0.0038 17.4 1.4 0.015 15.5 1.4 2.0 1 0 0 1 1 1 1 M-factor Ig_2 PF13895.6 RUS85371.1 - 2.7e-29 101.3 3.9 1.9e-07 31.3 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.6 RUS85371.1 - 3e-25 88.6 0.6 5e-07 30.2 0.1 5.2 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 RUS85371.1 - 5.5e-17 61.7 8.0 4.3e-05 23.6 0.0 5.6 5 2 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 RUS85371.1 - 1.3e-12 47.9 9.1 0.058 13.6 0.0 7.3 4 4 4 8 8 8 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 RUS85371.1 - 2.2e-10 40.5 0.1 0.14 12.3 0.0 4.4 4 0 0 4 4 4 3 Izumo-like Immunoglobulin domain I-set PF07679.16 RUS85371.1 - 5.3e-10 39.2 0.3 0.25 11.4 0.0 5.7 4 2 0 4 4 4 3 Immunoglobulin I-set domain Ig_4 PF16680.5 RUS85371.1 - 1.3e-09 38.2 0.1 0.25 11.6 0.0 4.8 5 0 0 5 5 5 4 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS85371.1 - 1e-07 32.2 0.1 3.9 7.9 0.0 4.9 5 1 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Lep_receptor_Ig PF06328.11 RUS85371.1 - 0.007 16.3 0.9 25 4.9 0.0 4.1 4 0 0 4 4 4 0 Ig-like C2-type domain Cupredoxin_1 PF13473.6 RUS85371.1 - 0.063 13.4 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Cupredoxin-like domain Pacs-1 PF10254.9 RUS85373.1 - 2.3e-135 451.8 3.1 7.6e-135 450.0 3.1 1.8 1 1 0 1 1 1 1 PACS-1 cytosolic sorting protein DUF2052 PF09747.9 RUS85373.1 - 0.081 13.1 11.8 0.021 15.0 5.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TPR_1 PF00515.28 RUS85374.1 - 6.7e-11 41.5 7.5 0.0012 18.5 0.0 5.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS85374.1 - 2e-09 36.8 15.0 0.00063 19.7 0.1 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85374.1 - 1.5e-08 34.2 6.4 0.031 14.5 0.4 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS85374.1 - 5.8e-08 32.9 2.2 2.6 9.1 0.0 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85374.1 - 2.4e-06 27.7 8.2 0.41 11.0 0.1 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS85374.1 - 6.5e-06 26.6 0.1 0.72 10.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS85374.1 - 0.00038 20.1 0.0 8.7 6.1 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 RUS85374.1 - 0.0044 17.3 3.3 0.85 10.1 0.1 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS85374.1 - 0.0096 15.9 13.8 1.4 9.1 0.0 6.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS85374.1 - 0.011 16.3 0.0 92 3.8 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 RUS85374.1 - 0.012 15.4 2.9 48 4.0 0.1 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.20 RUS85374.1 - 0.022 14.6 1.2 0.85 9.5 0.0 3.5 3 1 1 4 4 4 0 Region in Clathrin and VPS SNAP PF14938.6 RUS85374.1 - 0.036 13.5 10.5 3 7.2 0.3 3.7 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 RUS85374.1 - 0.089 13.0 9.8 12 6.2 0.3 4.7 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RUS85374.1 - 3.1 8.6 6.4 13 6.6 0.2 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat AAA PF00004.29 RUS85375.1 - 2.6e-42 144.4 0.0 5.7e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RUS85375.1 - 1.7e-10 40.7 0.1 3.4e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RUS85375.1 - 4.1e-09 36.1 0.2 7.7e-09 35.2 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RUS85375.1 - 6.5e-07 29.6 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RUS85375.1 - 3.5e-06 27.3 0.1 0.0018 18.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RUS85375.1 - 3.2e-05 23.2 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RUS85375.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RUS85375.1 - 7e-05 23.3 0.2 0.0031 17.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RUS85375.1 - 0.00011 22.1 0.2 0.00067 19.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RUS85375.1 - 0.0015 19.0 0.1 0.0049 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain Prot_ATP_OB_N PF17758.1 RUS85375.1 - 0.0018 17.9 0.1 0.0061 16.2 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 RUS85375.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 RUS85375.1 - 0.0037 17.4 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RUS85375.1 - 0.0041 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 RUS85375.1 - 0.005 16.5 0.3 0.33 10.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS85375.1 - 0.0058 16.9 0.1 0.014 15.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 RUS85375.1 - 0.0061 15.9 0.2 0.28 10.5 0.0 2.5 2 1 1 3 3 2 1 KaiC AAA_14 PF13173.6 RUS85375.1 - 0.0062 16.6 0.0 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RUS85375.1 - 0.013 15.3 0.3 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 RUS85375.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 RUS85375.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 RUS85375.1 - 0.016 14.6 0.0 0.079 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 RUS85375.1 - 0.032 13.7 0.0 0.094 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 RUS85375.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RUS85375.1 - 0.046 13.4 1.1 0.093 12.4 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RUS85375.1 - 0.053 13.2 0.2 0.15 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RUS85375.1 - 0.066 13.1 0.0 0.57 10.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 RUS85375.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RUS85375.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 RUS85375.1 - 0.13 11.5 0.2 0.51 9.5 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain ABC_tran PF00005.27 RUS85375.1 - 0.13 12.8 0.1 0.61 10.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Complex1_LYR_2 PF13233.6 RUS85376.1 - 0.68 10.7 4.8 1.3 9.8 4.8 1.5 1 1 0 1 1 1 0 Complex1_LYR-like DUF4536 PF15055.6 RUS85377.1 - 0.044 14.0 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) PRKCSH PF07915.13 RUS85378.1 - 8.8e-24 84.3 5.8 1.5e-14 54.8 1.2 2.6 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RUS85378.1 - 2.8e-09 36.9 1.3 5e-05 23.0 0.1 2.6 1 1 0 2 2 2 2 Glucosidase II beta subunit-like protein FbpA PF05833.11 RUS85379.1 - 3e-35 121.9 2.1 3e-35 121.9 2.1 2.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 RUS85379.1 - 5.7e-35 120.3 0.2 2e-34 118.5 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 RUS85379.1 - 2.2e-31 107.9 0.5 2.2e-31 107.9 0.5 2.9 3 0 0 3 3 3 1 NFACT protein C-terminal domain EGF PF00008.27 RUS85380.1 - 0.0011 19.2 23.4 0.0056 17.0 5.9 6.8 7 1 0 7 7 7 3 EGF-like domain hEGF PF12661.7 RUS85380.1 - 0.0026 18.3 4.3 0.0026 18.3 4.3 5.8 6 1 0 6 6 6 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS85380.1 - 0.024 15.0 6.0 0.024 15.0 6.0 5.2 5 1 0 5 5 5 0 EGF-like domain RWD PF05773.22 RUS85381.1 - 7.6e-20 71.3 0.0 7.6e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 RWD domain Pkinase PF00069.25 RUS85381.1 - 2.1e-19 69.9 3.7 2.1e-17 63.3 0.2 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85381.1 - 2.1e-12 46.9 0.2 5.3e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS85381.1 - 0.032 13.5 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like LMBR1 PF04791.16 RUS85381.1 - 0.31 9.9 0.4 0.4 9.5 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 RUS85382.1 - 5.7e-55 186.5 0.0 2.2e-35 122.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85382.1 - 1.3e-24 86.9 0.0 7.1e-12 45.2 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 RUS85382.1 - 8.1e-15 54.9 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 RUS85382.1 - 0.08 12.2 0.0 3.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Kinase-like zf-FCS PF06467.14 RUS85382.1 - 0.11 12.5 0.1 18 5.4 0.1 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif APH PF01636.23 RUS85382.1 - 0.21 11.5 0.6 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family HGTP_anticodon2 PF12745.7 RUS85383.1 - 7.6e-07 28.9 0.0 1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Anticodon binding domain of tRNAs Period_C PF12114.8 RUS85383.1 - 0.15 11.6 1.5 0.21 11.2 1.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Metallophos PF00149.28 RUS85384.1 - 8.5e-35 121.1 0.0 1.4e-34 120.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RUS85384.1 - 4.7e-30 103.7 0.2 1e-29 102.6 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 RUS85384.1 - 8.3e-13 47.6 5.3 4e-05 23.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS85384.1 - 5.9e-11 41.6 8.0 0.002 18.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS85384.1 - 2.3e-09 36.8 3.9 8.6e-05 22.1 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 RUS85384.1 - 2.9e-06 27.1 3.0 0.0034 17.5 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS85384.1 - 2.9e-05 24.1 0.0 0.00021 21.4 0.0 2.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS85384.1 - 6.8e-05 23.4 0.2 0.32 11.7 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS85384.1 - 9.3e-05 22.9 0.0 0.016 16.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS85384.1 - 0.0086 16.6 0.9 5.4 7.6 0.3 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85384.1 - 0.05 13.9 0.2 20 5.5 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS85384.1 - 0.074 13.7 0.4 8.5 7.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3791 PF12668.7 RUS85384.1 - 0.084 12.9 0.0 1.3 9.1 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3791) GP24_25 PF17388.2 RUS85384.1 - 0.27 11.2 1.2 29 4.6 0.2 3.1 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 TPR_17 PF13431.6 RUS85384.1 - 1.8 9.1 4.9 5 7.7 1.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_3_C PF01915.22 RUS85385.1 - 3.1e-42 144.8 0.0 4.7e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 RUS85385.1 - 1.1e-40 139.9 0.0 2.9e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 RUS85385.1 - 2e-09 37.4 0.0 5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain I-set PF07679.16 RUS85386.1 - 1.9e-28 98.3 0.1 3.2e-16 59.2 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS85386.1 - 6.2e-26 90.8 0.6 5.4e-15 55.8 0.2 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS85386.1 - 2.8e-24 85.3 0.7 1.5e-14 54.1 0.2 2.8 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS85386.1 - 4e-12 46.2 0.6 0.00031 20.9 0.1 3.3 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS85386.1 - 1.1e-11 44.8 0.5 0.041 14.1 0.0 4.4 3 2 2 5 5 5 3 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS85386.1 - 1.1e-07 32.2 0.2 0.00053 20.3 0.0 3.1 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS85386.1 - 8.4e-07 29.2 0.1 0.00067 19.9 0.0 3.2 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set PF05790.15 RUS85386.1 - 0.00048 20.3 0.1 2.1 8.6 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin C2-set domain Ig_6 PF18452.1 RUS85386.1 - 0.0016 18.0 0.0 0.0099 15.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS85386.1 - 0.005 16.9 0.6 0.14 12.2 0.0 2.9 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 RUS85386.1 - 0.0065 16.5 0.2 0.044 13.8 0.1 2.4 2 1 0 2 2 2 1 C17orf99 Ig domain Adeno_E3_CR1 PF02440.15 RUS85386.1 - 0.011 15.4 1.3 0.031 14.1 0.2 2.3 2 2 0 2 2 2 0 Adenovirus E3 region protein CR1 RXT2_N PF08595.11 RUS85387.1 - 0.021 14.8 2.6 0.023 14.7 2.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RUS85387.1 - 0.037 13.2 18.8 0.043 13.0 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 RUS85387.1 - 0.13 12.5 11.1 0.16 12.2 11.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RUS85387.1 - 0.35 10.1 19.3 0.48 9.7 19.3 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 RUS85387.1 - 0.84 8.1 6.0 0.88 8.0 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 RUS85387.1 - 0.89 8.5 9.5 1.2 8.1 9.5 1.2 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 RUS85387.1 - 1.4 8.3 8.1 1.7 8.0 8.1 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 RUS85387.1 - 3.2 5.7 5.1 3.5 5.6 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 RUS85387.1 - 3.2 7.6 8.9 4.1 7.2 8.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RUS85387.1 - 5.7 5.0 10.1 6.4 4.8 10.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS85387.1 - 6.4 4.9 9.8 7.8 4.7 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ion_trans PF00520.31 RUS85388.1 - 0.28 10.4 19.8 2.5 7.3 19.8 2.2 1 1 0 1 1 1 0 Ion transport protein Vps39_2 PF10367.9 RUS85389.1 - 0.12 12.9 1.7 0.35 11.3 0.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Ank_2 PF12796.7 RUS85390.1 - 9.6e-29 99.8 9.3 3.1e-10 40.5 0.2 3.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS85390.1 - 1.4e-26 89.6 8.6 0.0013 19.0 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 RUS85390.1 - 1.2e-24 86.4 10.6 1.5e-08 35.0 0.0 5.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS85390.1 - 3.1e-22 78.3 10.2 7.2e-09 35.7 0.1 6.3 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS85390.1 - 1.2e-13 50.9 20.4 4.3e-05 23.8 0.2 7.7 7 1 0 7 7 7 3 Ankyrin repeat TMEM223 PF14640.6 RUS85391.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 223 DUF1542 PF07564.11 RUS85392.1 - 0.0021 18.1 2.8 0.0042 17.2 2.8 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) Me-amine-dh_L PF02975.14 RUS85392.1 - 0.05 14.1 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Borrelia_P83 PF05262.11 RUS85392.1 - 0.3 9.5 12.8 0.28 9.6 12.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cnd1_N PF12922.7 RUS85392.1 - 9.3 6.1 9.7 9.7 6.0 8.7 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term S-AdoMet_synt_C PF02773.16 RUS85393.1 - 2.3e-64 215.5 0.1 1.5e-62 209.7 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RUS85393.1 - 2.5e-46 156.8 0.0 5.9e-46 155.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RUS85393.1 - 1.5e-37 128.3 0.4 3.1e-37 127.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 RUS85393.1 - 0.036 12.9 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) CaMKII_AD PF08332.10 RUS85394.1 - 4.1e-55 185.4 0.0 9.4e-55 184.2 0.0 1.6 2 0 0 2 2 2 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase PF00069.25 RUS85394.1 - 7.9e-55 186.1 0.0 1.5e-54 185.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85394.1 - 6.6e-21 74.8 0.0 8.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.6 RUS85394.1 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 RUS85394.1 - 1.2e-05 25.5 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Pkinase_fungal PF17667.1 RUS85394.1 - 0.00014 20.7 0.0 0.00037 19.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RUS85394.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Importin_rep_5 PF18816.1 RUS85394.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Importin repeat RSS_P20 PF11757.8 RUS85394.1 - 0.14 12.6 2.1 0.65 10.5 0.4 2.4 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Trypan_PARP PF05887.11 RUS85395.1 - 0.00073 19.5 2.5 0.0072 16.3 1.6 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) CopC PF04234.12 RUS85395.1 - 0.53 11.4 3.4 1.7 9.8 0.2 3.3 2 2 0 2 2 2 0 CopC domain FA PF08736.11 RUS85395.1 - 0.59 10.3 3.3 53 4.0 0.0 3.3 2 1 1 3 3 3 0 FERM adjacent (FA) UPA PF17217.3 RUS85396.1 - 3.5e-51 172.8 0.0 5.3e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 RUS85396.1 - 4.4e-32 110.3 0.0 9e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 RUS85396.1 - 2.4e-17 62.9 0.1 5.2e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.19 RUS85397.1 - 1e-13 51.3 10.0 1.9e-13 50.4 10.0 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain DUF3827 PF12877.7 RUS85397.1 - 8.1e-05 21.2 0.0 8.8e-05 21.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 RUS85397.1 - 0.0023 18.8 0.2 0.005 17.7 0.0 1.7 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RUS85397.1 - 0.0082 16.0 0.2 0.0094 15.9 0.2 1.3 1 1 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 RUS85397.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FAM176 PF14851.6 RUS85397.1 - 0.031 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 FAM176 family AMA-1 PF02430.15 RUS85397.1 - 0.032 13.2 0.1 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 RCR PF12273.8 RUS85397.1 - 0.04 14.6 3.6 0.076 13.7 0.4 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MIG-14_Wnt-bd PF06664.12 RUS85397.1 - 0.057 12.6 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DAP10 PF07213.11 RUS85397.1 - 0.064 13.2 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 DAP10 membrane protein DUF4381 PF14316.6 RUS85397.1 - 0.078 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmD PF04995.14 RUS85397.1 - 0.13 12.4 0.7 0.22 11.6 0.7 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SIT PF15330.6 RUS85397.1 - 0.13 12.7 0.2 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Birna_VP3 PF01767.16 RUS85397.1 - 0.15 12.2 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein Ig_3 PF13927.6 RUS85398.1 - 5.7e-05 23.6 0.7 0.021 15.4 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS85398.1 - 0.033 14.3 0.1 0.089 13.0 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain NOA36 PF06524.12 RUS85399.1 - 0.33 10.2 8.7 0.45 9.8 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 RUS85399.1 - 0.99 8.6 3.9 1.3 8.1 3.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SHIPPO-rpt PF07004.12 RUS85400.1 - 1.2e-18 67.0 47.2 0.15 13.0 0.1 12.5 12 0 0 12 12 12 10 Sperm-tail PG-rich repeat HMMR_N PF15905.5 RUS85400.1 - 1.2 8.5 5.4 3.5 7.0 0.1 3.3 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor N-terminal 3Beta_HSD PF01073.19 RUS85401.1 - 3e-68 229.9 0.0 3.7e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 RUS85401.1 - 2.7e-29 102.4 0.1 3.6e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS85401.1 - 1.9e-13 50.6 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS85401.1 - 1.2e-12 47.5 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RUS85401.1 - 9.1e-10 38.7 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 RUS85401.1 - 4.8e-08 32.5 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS85401.1 - 4.4e-07 29.3 0.0 4.4e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 RUS85401.1 - 0.047 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF2939 PF11159.8 RUS85402.1 - 0.00035 20.9 0.1 0.075 13.5 0.1 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2939) DUF445 PF04286.12 RUS85402.1 - 0.0042 16.9 0.1 0.0048 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Speriolin_N PF15058.6 RUS85402.1 - 0.0092 16.1 18.4 0.41 10.7 18.4 2.1 1 1 0 1 1 1 1 Speriolin N terminus DUF3819 PF12842.7 RUS85402.1 - 0.12 12.3 2.3 2.5 8.0 2.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) CEL_III_C PF18054.1 RUS85402.1 - 0.6 10.2 2.3 1.3 9.0 2.3 1.7 1 1 0 1 1 1 0 CEL-III C-terminal TFCD_C PF12612.8 RUS85402.1 - 0.73 9.6 8.8 36 4.1 8.8 2.5 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal CCDC117 PF15810.5 RUS85402.1 - 1.7 9.0 9.5 5.4e+02 0.8 9.5 2.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 117 GCP_C_terminal PF04130.13 RUS85402.1 - 1.7 8.0 10.4 6.3 6.2 10.4 1.8 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal SecD_SecF PF02355.16 RUS85402.1 - 6.5 6.1 10.7 3.1e+02 0.6 10.7 2.1 1 1 0 1 1 1 0 Protein export membrane protein Big_3_3 PF13750.6 RUS85402.1 - 7.5 6.2 12.9 4 7.1 4.7 3.0 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) DNA_pol_phi PF04931.13 RUS85404.1 - 0.00082 17.6 35.6 0.001 17.3 35.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi Vfa1 PF08432.10 RUS85404.1 - 0.083 13.2 2.6 0.15 12.4 2.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 RUS85404.1 - 0.25 9.6 19.9 0.31 9.3 19.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS85404.1 - 0.41 10.0 26.5 0.52 9.7 26.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS85404.1 - 1 7.5 28.7 1.3 7.1 28.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS85404.1 - 1.4 8.1 22.7 1.8 7.8 22.7 1.1 1 0 0 1 1 1 0 BUD22 cNMP_binding PF00027.29 RUS85405.1 - 1.1e-32 111.9 0.3 3.4e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lipase_GDSL PF00657.22 RUS85406.1 - 2.6e-12 47.1 0.0 1.3e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RUS85406.1 - 2.1e-08 34.8 0.1 4.2e-08 33.8 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3357 PF11837.8 RUS85407.1 - 0.019 15.4 0.2 0.056 13.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SP_C-Propep PF08999.10 RUS85407.1 - 1.3 8.9 7.3 2.4 8.0 7.3 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide zf-C2H2 PF00096.26 RUS85408.1 - 3.8e-14 52.2 32.4 0.0001 22.6 3.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS85408.1 - 7.1e-14 51.3 29.4 4.5e-07 29.5 1.4 5.0 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS85408.1 - 1.7e-09 37.7 27.1 0.0015 19.2 3.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS85408.1 - 1.9e-08 34.4 28.6 6.3e-07 29.5 0.8 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-Di19 PF05605.12 RUS85408.1 - 4.5e-07 30.1 16.9 0.00027 21.2 2.5 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS85408.1 - 0.0019 18.5 12.2 1 9.8 0.4 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS85408.1 - 0.057 13.2 0.4 0.057 13.2 0.4 3.8 3 1 1 4 4 4 0 zinc-finger C2H2-type OrsD PF12013.8 RUS85408.1 - 0.1 13.0 13.6 0.13 12.7 0.1 4.0 3 1 2 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1390 PF07150.11 RUS85408.1 - 0.2 11.3 3.4 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) zf-C2H2_jaz PF12171.8 RUS85408.1 - 0.21 11.9 6.9 43 4.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Lar_restr_allev PF14354.6 RUS85408.1 - 0.25 11.8 7.5 1.2 9.6 0.9 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf_C2H2_ZHX PF18387.1 RUS85408.1 - 0.29 10.8 6.2 2.7 7.7 1.4 2.7 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_4 PF14447.6 RUS85408.1 - 1.9 8.4 7.0 0.6 10.0 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 RUS85408.1 - 2.6 8.4 10.7 5.1 7.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon Ribosomal_L37ae PF01780.19 RUS85408.1 - 3.2 7.9 6.3 6.1 7.0 0.3 2.9 1 1 2 3 3 3 0 Ribosomal L37ae protein family DUF2225 PF09986.9 RUS85408.1 - 4.6 6.9 8.8 3.9 7.1 0.2 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_C2H2_10 PF18414.1 RUS85408.1 - 4.7 6.8 6.5 36 4.0 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger Kunitz_BPTI PF00014.23 RUS85409.1 - 3.8e-89 292.8 63.5 3.7e-20 71.9 3.8 5.1 4 1 1 5 5 5 5 Kunitz/Bovine pancreatic trypsin inhibitor domain WW PF00397.26 RUS85409.1 - 0.00073 19.6 2.8 0.31 11.2 0.1 3.8 4 0 0 4 4 4 2 WW domain OCRE PF17780.1 RUS85409.1 - 0.34 11.0 5.6 12 6.0 0.1 3.8 4 0 0 4 4 4 0 OCRE domain Methyltransf_15 PF09445.10 RUS85409.1 - 0.56 9.8 7.9 27 4.3 0.1 4.2 4 0 0 4 4 4 0 RNA cap guanine-N2 methyltransferase Lipase PF00151.19 RUS85410.1 - 2.1e-48 165.4 0.3 1.2e-27 97.2 0.1 3.1 2 1 1 3 3 3 3 Lipase ATP-synt_C PF00137.21 RUS85410.1 - 0.22 11.9 0.3 0.4 11.1 0.3 1.4 1 0 0 1 1 1 0 ATP synthase subunit C ShK PF01549.24 RUS85411.1 - 0.00044 20.7 3.9 0.00082 19.9 3.9 1.5 1 0 0 1 1 1 1 ShK domain-like Ldl_recept_b PF00058.17 RUS85411.1 - 0.1 13.1 0.2 0.81 10.2 0.1 2.3 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Ldl_recept_b PF00058.17 RUS85412.1 - 2.9e-16 59.7 0.2 1.4e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor repeat class B Tme5_EGF_like PF09064.10 RUS85412.1 - 0.0076 16.1 5.1 0.015 15.2 5.1 1.5 1 0 0 1 1 1 1 Thrombomodulin like fifth domain, EGF-like Ldl_recept_b PF00058.17 RUS85413.1 - 1.5e-34 118.1 13.7 1.5e-06 28.6 1.2 8.7 9 0 0 9 9 9 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 RUS85413.1 - 6.1e-12 45.6 22.5 3.3e-06 27.3 5.6 2.4 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site SGL PF08450.12 RUS85413.1 - 1.5e-07 31.3 8.9 0.023 14.3 2.2 5.5 2 2 2 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 RUS85413.1 - 3.3e-07 30.1 9.5 0.00029 20.7 2.1 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like Insulin_TMD PF17870.1 RUS85413.1 - 0.0046 17.0 2.8 0.01 15.9 2.8 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EGF PF00008.27 RUS85413.1 - 0.027 14.8 15.8 0.33 11.3 1.0 2.5 2 0 0 2 2 2 0 EGF-like domain RIFIN PF02009.16 RUS85413.1 - 0.053 13.4 7.1 0.012 15.5 3.8 1.6 2 0 0 2 2 2 0 Rifin Orf78 PF06024.12 RUS85413.1 - 0.077 13.3 2.0 0.096 13.0 0.2 2.0 2 0 0 2 2 2 0 Orf78 (ac78) APP_amyloid PF10515.9 RUS85413.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus Plasmod_Pvs28 PF06247.11 RUS85413.1 - 1.5 9.1 13.2 0.71 10.2 1.4 2.7 2 0 0 2 2 2 0 Pvs28 EGF domain TMEM154 PF15102.6 RUS85413.1 - 5.4 6.9 16.7 0.14 12.0 1.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family Tme5_EGF_like PF09064.10 RUS85413.1 - 7 6.6 14.9 7.2 6.6 2.4 2.5 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like TFIID_30kDa PF03540.13 RUS85414.1 - 0.016 15.2 13.0 13 5.9 0.3 6.1 1 1 5 6 6 6 0 Transcription initiation factor TFIID 23-30kDa subunit Castor1_N PF18700.1 RUS85415.1 - 0.0004 20.1 0.5 14 5.6 0.1 4.4 2 1 2 4 4 4 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain zf-C2HC_2 PF13913.6 RUS85415.1 - 0.083 12.8 0.9 2.8e+02 1.5 0.0 5.4 7 0 0 7 7 7 0 zinc-finger of a C2HC-type DUF4803 PF16061.5 RUS85415.1 - 0.14 11.6 2.6 0.17 11.3 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4803) AAA_33 PF13671.6 RUS85415.1 - 0.27 11.4 3.2 0.81 9.8 3.2 2.0 1 1 0 1 1 1 0 AAA domain zf-C2H2_9 PF16293.5 RUS85415.1 - 5.7 6.9 16.2 4.1 7.3 1.2 4.0 2 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) ANF_receptor PF01094.28 RUS85416.1 - 0.015 14.4 0.6 0.021 13.9 0.6 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region ANF_receptor PF01094.28 RUS85417.1 - 0.031 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Receptor family ligand binding region EphA2_TM PF14575.6 RUS85417.1 - 8.7 7.3 6.0 6.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Guanylate_cyc PF00211.20 RUS85418.1 - 4.3e-33 114.5 0.2 1.1e-32 113.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS85418.1 - 1.2e-23 83.8 1.5 7.9e-18 64.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS85418.1 - 4.3e-18 65.6 0.3 1.1e-16 61.1 0.2 2.2 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 RUS85418.1 - 3e-08 33.4 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated TFIID-18kDa PF02269.16 RUS85418.1 - 0.056 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1997 PF09366.10 RUS85421.1 - 0.067 13.3 1.3 18 5.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1997) DUF4566 PF15130.6 RUS85421.1 - 0.18 11.2 5.0 56 3.0 0.1 4.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4566) tRNA-synt_1g PF09334.11 RUS85422.1 - 5.9e-66 222.8 3.4 1.5e-43 149.0 0.7 3.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RUS85422.1 - 4e-15 55.1 0.7 2.7e-09 35.9 0.0 2.9 1 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RUS85422.1 - 0.0053 16.2 0.0 0.0075 15.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MMgT PF10270.9 RUS85423.1 - 1.6e-16 60.5 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter V_ATPase_I PF01496.19 RUS85423.1 - 0.061 11.2 0.0 0.081 10.8 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2976 PF11190.8 RUS85423.1 - 0.12 12.2 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PID_2 PF14719.6 RUS85424.1 - 3.6e-19 69.3 0.3 4.3e-19 69.1 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 RUS85424.1 - 6.5e-07 29.5 0.1 0.0027 17.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) FYVE PF01363.21 RUS85425.1 - 1.1e-13 51.1 8.4 2.7e-13 49.9 8.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 RUS85425.1 - 2.3e-09 37.7 7.3 0.18 12.8 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat DUF2688 PF10892.8 RUS85425.1 - 0.31 10.6 4.8 1.1 8.8 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2688) adh_short PF00106.25 RUS85426.1 - 5.3e-26 91.3 0.3 2.8e-24 85.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS85426.1 - 9.1e-16 58.1 0.0 4.7e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS85426.1 - 2.2e-10 40.7 0.1 3.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS85426.1 - 0.0034 16.9 0.1 0.0052 16.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS85426.1 - 0.0064 15.9 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 RUS85426.1 - 0.088 12.2 0.0 0.27 10.6 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1978 PF09321.10 RUS85429.1 - 0.13 11.6 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) MFS_1 PF07690.16 RUS85430.1 - 1.2e-25 90.3 28.6 4.7e-18 65.2 14.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.9 RUS85431.1 - 0.0017 18.0 4.5 0.0018 17.9 4.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF5470 PF17564.2 RUS85431.1 - 0.12 12.6 1.0 0.18 12.0 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5470) IMUP PF15761.5 RUS85431.1 - 0.49 11.1 8.8 0.72 10.6 8.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 RUS85431.1 - 7.9 6.8 14.0 11 6.3 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) KASH PF10541.9 RUS85432.1 - 0.019 15.2 2.4 0.063 13.5 1.4 2.2 2 0 0 2 2 2 0 Nuclear envelope localisation domain 7tm_1 PF00001.21 RUS85433.1 - 2.6e-82 276.1 1.8 3.3e-82 275.8 1.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS85433.1 - 5.4e-11 42.4 11.8 1e-07 31.6 8.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS85433.1 - 8.8e-06 25.5 8.8 1.7e-05 24.6 8.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS85433.1 - 0.00015 21.7 9.7 0.00048 20.0 7.7 2.3 2 1 0 2 2 2 1 Olfactory receptor DUF2062 PF09835.9 RUS85433.1 - 0.8 9.5 8.0 13 5.6 6.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Trypsin PF00089.26 RUS85434.1 - 1.4e-35 123.1 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF5327 PF17261.2 RUS85435.1 - 0.35 11.6 2.8 0.86 10.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF5401 PF17380.2 RUS85436.1 - 0.14 10.2 0.2 0.17 9.9 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Dpy-30 PF05186.13 RUS85437.1 - 1.3e-10 40.8 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Selenoprotein_S PF06936.11 RUS85437.1 - 0.69 9.7 12.8 0.89 9.3 12.8 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) SURF2 PF05477.11 RUS85437.1 - 3 7.5 14.8 4.2 7.0 14.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CAP PF00188.26 RUS85438.1 - 5.9e-10 40.1 0.3 5.9e-10 40.1 0.3 3.4 2 2 0 2 2 2 1 Cysteine-rich secretory protein family Reprolysin_5 PF13688.6 RUS85439.1 - 2.5e-06 27.8 0.0 4.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS85439.1 - 9.4e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 RUS85439.1 - 8.4e-05 22.6 0.0 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 RUS85439.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS85439.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3281 PF11685.8 RUS85439.1 - 0.13 11.6 0.1 0.4 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3281) zf-RVT PF13966.6 RUS85440.1 - 6.8e-07 29.9 2.1 1.1e-06 29.2 2.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FAD_binding_4 PF01565.23 RUS85440.1 - 7.6e-07 28.9 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain YdjO PF14169.6 RUS85440.1 - 0.087 12.6 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO eIF-3c_N PF05470.12 RUS85440.1 - 0.28 9.4 1.3 0.29 9.4 1.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RUS85440.1 - 0.85 7.7 16.9 1.1 7.4 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS85440.1 - 1.4 6.9 32.3 2 6.4 32.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RUS85440.1 - 5.8 6.2 13.0 7.3 5.8 13.0 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 RUS85440.1 - 6.8 6.4 10.4 11 5.7 10.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Q_salvage PF10343.9 RUS85441.1 - 1.4e-112 375.9 0.1 1.6e-112 375.7 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4539 PF15072.6 RUS85442.1 - 1.1e-21 76.7 0.0 1.8e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) ShK PF01549.24 RUS85443.1 - 5.5e-09 36.4 38.3 5.5e-05 23.6 5.5 7.3 8 2 0 8 8 8 3 ShK domain-like VWC PF00093.18 RUS85443.1 - 1.1e-06 28.8 161.1 0.0013 19.0 13.6 8.2 7 1 0 7 7 7 6 von Willebrand factor type C domain 60KD_IMP PF02096.20 RUS85444.1 - 6.4e-24 84.7 9.7 9.6e-24 84.1 9.7 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF382 PF04037.13 RUS85444.1 - 0.15 12.2 0.3 0.33 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF382) AdoHcyase PF05221.17 RUS85445.1 - 3.9e-136 453.0 0.0 3.8e-132 440.0 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RUS85445.1 - 6.6e-83 276.6 0.5 1.1e-82 275.9 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS85445.1 - 2.9e-08 33.3 0.0 5.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RUS85445.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 RUS85445.1 - 0.0045 17.2 0.1 0.008 16.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 RUS85445.1 - 0.018 15.4 0.1 0.044 14.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 RUS85445.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.18 RUS85445.1 - 0.078 12.6 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Shikimate_DH PF01488.20 RUS85445.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase vATP-synt_AC39 PF01992.16 RUS85446.1 - 8.6e-112 374.0 0.5 9.6e-112 373.8 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Lectin_C PF00059.21 RUS85447.1 - 2.5e-11 44.2 0.6 2.5e-11 44.2 0.6 2.0 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 RUS85447.1 - 0.0006 19.5 2.5 0.0063 16.2 1.9 2.6 2 1 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like DUF3377 PF11857.8 RUS85447.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.6 RUS85447.1 - 0.038 14.9 0.0 0.084 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4476 PF14771.6 RUS85448.1 - 1.7e-07 31.4 0.0 0.0033 17.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) Snf7 PF03357.21 RUS85449.1 - 1.6e-09 37.6 15.6 1.6e-09 37.6 15.6 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 RUS85449.1 - 0.0022 18.0 6.3 0.0035 17.3 6.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1864 PF08933.11 RUS85449.1 - 0.034 12.9 1.6 0.042 12.6 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1864) UPF0176_N PF17773.1 RUS85449.1 - 0.048 14.0 1.5 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 UPF0176 acylphosphatase like domain CbiG_C PF01890.16 RUS85449.1 - 0.28 11.8 2.7 6.6 7.3 0.8 2.6 2 1 0 2 2 2 0 Cobalamin synthesis G C-terminus PCI PF01399.27 RUS85449.1 - 0.35 11.4 3.8 2.8 8.5 0.6 3.0 2 1 1 3 3 3 0 PCI domain DMSP_lyase PF16867.5 RUS85449.1 - 0.41 10.3 1.7 0.51 10.0 0.0 2.0 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase YusW PF14039.6 RUS85449.1 - 0.78 10.3 6.2 1.1 9.8 0.9 2.6 2 1 0 2 2 2 0 YusW-like protein BshC PF10079.9 RUS85449.1 - 2.5 6.7 11.7 0.033 12.9 0.7 2.0 1 1 0 2 2 2 0 Bacillithiol biosynthesis BshC Y2_Tnp PF04986.13 RUS85449.1 - 2.6 8.0 5.5 3.5 7.7 2.2 2.0 1 1 1 2 2 2 0 Putative transposase HK97-gp10_like PF04883.12 RUS85449.1 - 6.1 7.9 7.3 57 4.8 0.0 3.3 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component LicD PF04991.13 RUS85450.1 - 5.7e-13 49.5 4.3 5.3e-07 30.0 2.2 2.2 1 1 1 2 2 2 2 LicD family AvrPto PF11592.8 RUS85450.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto mRNA_decap_C PF16741.5 RUS85451.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus SpoIIIAH PF12685.7 RUS85451.1 - 0.13 12.0 1.7 0.17 11.7 1.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 RUS85451.1 - 0.27 10.6 31.3 0.37 10.2 31.3 1.1 1 0 0 1 1 1 0 SDA1 Transposase_1 PF01359.18 RUS85452.1 - 8.7e-06 25.5 2.0 8.7e-06 25.5 2.0 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 RUS85452.1 - 7.5e-05 22.9 0.3 0.00013 22.1 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS85452.1 - 0.00072 20.1 0.6 0.0028 18.2 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS85452.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS85452.1 - 0.0061 16.5 0.1 0.0093 15.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) DUF4817 PF16087.5 RUS85452.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) zf-H2C2_2 PF13465.6 RUS85453.1 - 7.3e-55 181.1 128.6 5e-07 29.9 1.4 18.6 19 0 0 19 19 19 15 Zinc-finger double domain zf-C2H2 PF00096.26 RUS85453.1 - 1.7e-50 166.7 143.5 1.9e-05 24.9 0.7 18.2 18 0 0 18 18 18 18 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS85453.1 - 2.6e-45 149.1 143.6 0.00017 22.1 0.6 18.2 18 0 0 18 18 18 18 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS85453.1 - 8.3e-21 73.8 101.6 0.001 19.3 0.4 17.4 18 0 0 18 18 17 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS85453.1 - 1.2e-09 38.2 122.9 0.056 13.8 0.3 17.8 18 0 0 18 18 18 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS85453.1 - 2e-09 37.2 141.8 0.00072 19.5 2.6 18.3 18 0 0 18 18 18 9 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS85453.1 - 0.0015 18.8 69.7 0.044 14.1 3.7 8.6 1 1 8 9 9 9 4 C2H2-type zinc ribbon zf-Di19 PF05605.12 RUS85453.1 - 0.007 16.6 2.5 0.007 16.6 2.5 10.6 4 2 7 12 12 12 4 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 RUS85453.1 - 0.014 15.9 0.1 0.014 15.9 0.1 16.4 7 4 9 16 16 15 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 RUS85453.1 - 0.046 14.0 31.0 2.3 8.5 0.8 9.3 3 3 5 8 8 8 0 BolA-like protein PyrI_C PF02748.15 RUS85453.1 - 0.066 13.1 38.0 1.5 8.8 0.1 10.2 9 3 2 11 11 11 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FerB PF08150.12 RUS85453.1 - 0.066 13.8 2.3 0.73 10.5 0.2 3.1 2 0 0 2 2 2 0 FerB (NUC096) domain zf-C2H2_3rep PF18868.1 RUS85453.1 - 2.9 8.6 75.1 13 6.5 0.3 12.4 1 1 8 11 11 11 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 RUS85453.1 - 6.3 6.7 13.5 8.5 6.3 1.5 5.3 5 1 1 6 6 6 0 GAGA factor Pkinase PF00069.25 RUS85454.1 - 7.9e-18 64.8 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 RUS85454.1 - 2.8e-09 37.4 11.3 0.012 16.4 0.6 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 RUS85454.1 - 4.7e-07 29.4 0.0 1.6e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 RUS85454.1 - 0.003 16.2 0.1 0.42 9.1 0.0 2.5 2 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 RUS85454.1 - 0.04 14.2 2.5 49 4.6 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 RUS85454.1 - 0.046 14.1 0.5 14 6.2 0.0 3.6 3 1 0 3 3 3 0 HEAT repeats Arm_2 PF04826.13 RUS85454.1 - 0.053 13.0 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Armadillo-like ANAPC4_WD40 PF12894.7 RUS85454.1 - 0.059 13.7 0.0 3.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Acyl_transf_3 PF01757.22 RUS85455.1 - 3.1e-20 72.5 32.0 3.1e-20 72.5 32.0 1.8 2 0 0 2 2 2 1 Acyltransferase family DUF418 PF04235.12 RUS85455.1 - 7.9 6.4 16.6 0.021 14.8 5.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF418) 7tm_1 PF00001.21 RUS85456.1 - 1.9e-53 181.5 23.3 2.2e-53 181.3 23.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS85456.1 - 1.6e-09 37.6 18.6 1.9e-09 37.3 18.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS85456.1 - 4.5e-08 32.8 14.5 8.9e-08 31.8 14.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RUS85456.1 - 2.8e-07 30.5 14.3 7e-06 26.0 14.3 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS85456.1 - 1.9e-06 27.7 22.1 4.8e-06 26.4 22.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Voltage_CLC PF00654.20 RUS85456.1 - 0.0057 16.0 3.8 0.0057 16.0 3.8 2.1 2 0 0 2 2 2 1 Voltage gated chloride channel SNF PF00209.18 RUS85457.1 - 5.6e-179 596.2 28.2 1.7e-178 594.6 28.2 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family AbiEi_2 PF09952.9 RUS85458.1 - 0.47 10.7 2.0 55 4.0 0.1 3.1 2 2 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Pet191_N PF10203.9 RUS85458.1 - 0.73 10.2 7.6 12 6.2 0.3 2.9 1 1 3 4 4 4 0 Cytochrome c oxidase assembly protein PET191 PRTase_1 PF11202.8 RUS85458.1 - 4.6 6.4 15.3 13 4.9 0.5 5.1 1 1 4 6 6 6 0 Phosphoribosyl transferase (PRTase) DUF4686 PF15742.5 RUS85459.1 - 5.1e-38 131.2 67.4 5.1e-38 131.2 67.4 8.7 2 2 5 7 7 7 1 Domain of unknown function (DUF4686) KELK PF15796.5 RUS85459.1 - 0.00016 22.0 7.4 0.00016 22.0 7.4 22.7 10 4 14 25 25 25 3 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-F_leu_zip PF10473.9 RUS85459.1 - 0.0072 16.4 17.0 0.0072 16.4 17.0 18.6 4 4 12 19 19 19 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4248 PF14053.6 RUS85459.1 - 3.2 7.8 8.6 44 4.2 0.1 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4248) VBS PF08913.10 RUS85459.1 - 5.7 7.4 9.5 0.25 11.8 0.6 3.6 3 0 0 3 3 3 0 Vinculin Binding Site AhpC-TSA_2 PF13911.6 RUS85460.1 - 2.5e-05 24.3 0.2 3.5e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme MRP-L47 PF06984.13 RUS85461.1 - 1.9e-32 111.3 1.0 3.2e-32 110.5 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) PPL5 PF18168.1 RUS85461.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF3585 PF12130.8 RUS85461.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.0 3 0 0 3 3 3 0 Bivalent Mical/EHBP Rab binding domain HLH PF00010.26 RUS85462.1 - 1.2e-15 57.2 3.3 2.6e-15 56.1 3.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS85462.1 - 1.4e-09 38.0 0.1 4.2e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Hairy Orange Scramblase PF03803.15 RUS85463.1 - 1.3e-60 204.4 0.4 1e-42 145.9 0.0 2.0 2 0 0 2 2 2 2 Scramblase DNA_pol_phi PF04931.13 RUS85463.1 - 0.0084 14.3 39.2 0.011 13.9 39.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 RUS85463.1 - 0.14 10.6 17.4 0.17 10.3 17.4 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS85463.1 - 0.22 9.7 27.3 0.28 9.3 27.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS85463.1 - 0.45 9.9 26.1 0.58 9.5 26.1 1.1 1 0 0 1 1 1 0 SDA1 CNDH2_C PF16858.5 RUS85463.1 - 1.1 9.1 10.4 1.6 8.6 10.4 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RRN3 PF05327.11 RUS85463.1 - 1.3 7.5 23.0 1.7 7.1 23.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 RUS85463.1 - 2.1 6.5 22.6 2.8 6.1 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 RUS85463.1 - 3.8 7.0 22.4 5.3 6.5 22.4 1.2 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 RUS85463.1 - 5 6.4 19.0 7.2 5.9 19.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AA_permease_2 PF13520.6 RUS85464.1 - 7.7e-43 146.9 19.7 7.7e-43 146.9 19.7 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 RUS85464.1 - 7.5e-36 123.7 19.4 7.5e-36 123.7 19.4 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RUS85464.1 - 2.1e-21 75.7 7.5 2.1e-21 75.7 7.5 3.1 3 1 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.6 RUS85465.1 - 7.2e-09 35.0 6.3 7.9e-09 34.8 6.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS85465.1 - 1.5e-07 30.4 4.9 1.8e-07 30.1 4.9 1.0 1 0 0 1 1 1 1 Amino acid permease Trep_Strep PF09605.10 RUS85465.1 - 0.017 15.1 3.5 0.019 15.0 3.5 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) B277 PF17623.2 RUS85465.1 - 0.21 10.6 0.1 0.22 10.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF4358 PF14270.6 RUS85468.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Peptidase_C2 PF00648.21 RUS85469.1 - 4.3e-87 291.9 0.0 6.3e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.18 RUS85469.1 - 5.4e-08 32.0 52.8 0.00049 19.4 4.9 5.1 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others Carb_anhydrase PF00194.21 RUS85471.1 - 1.1e-69 234.8 0.0 1.4e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Fibrinogen_C PF00147.18 RUS85474.1 - 1.9e-55 188.1 5.7 3.3e-55 187.3 5.7 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS85474.1 - 0.0031 17.4 7.4 0.014 15.3 7.1 1.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain GvpL_GvpF PF06386.11 RUS85474.1 - 0.0039 17.2 1.7 0.38 10.6 1.4 2.4 2 0 0 2 2 2 1 Gas vesicle synthesis protein GvpL/GvpF Baculo_PEP_C PF04513.12 RUS85474.1 - 0.011 15.8 13.5 0.74 9.9 1.7 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trimer_CC PF08954.11 RUS85474.1 - 0.042 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Trimerisation motif ApoLp-III PF07464.11 RUS85474.1 - 0.13 12.4 8.8 1.3 9.1 6.8 2.8 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3150 PF11348.8 RUS85474.1 - 0.35 10.1 4.1 0.76 9.0 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) YtxH PF12732.7 RUS85474.1 - 0.77 10.3 3.1 18 5.9 0.3 2.5 2 0 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 RUS85474.1 - 1 10.0 4.6 4.7 7.9 0.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DASH_Dam1 PF08653.10 RUS85474.1 - 2.3 8.1 4.8 21 5.0 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 ACCA PF03255.14 RUS85474.1 - 2.8 7.8 5.2 17 5.3 1.0 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fzo_mitofusin PF04799.13 RUS85474.1 - 3 7.4 7.9 9 5.8 0.2 2.6 1 1 0 2 2 2 0 fzo-like conserved region DUF842 PF05811.13 RUS85474.1 - 4.3 7.0 6.2 4.7 6.9 1.1 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Kinesin PF00225.23 RUS85475.1 - 2.2e-31 109.0 0.0 2.5e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS85475.1 - 2.2e-25 89.3 0.0 2.7e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 RUS85476.1 - 8.3e-19 67.7 0.0 8.3e-19 67.7 0.0 2.8 2 1 1 3 3 3 1 Kinesin motor domain Ependymin PF00811.18 RUS85477.1 - 3.8e-15 56.3 0.0 6.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Ependymin zf-RING_2 PF13639.6 RUS85478.1 - 6.8e-10 39.1 12.5 1.2e-09 38.3 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RUS85478.1 - 4.9e-08 33.1 12.1 1.7e-07 31.4 12.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RUS85478.1 - 2.8e-06 27.1 12.4 5e-06 26.3 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS85478.1 - 5.7e-06 26.1 11.5 1e-05 25.3 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS85478.1 - 6.1e-05 23.0 8.6 0.00014 21.8 8.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RUS85478.1 - 8.2e-05 22.2 5.7 0.00017 21.2 5.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RUS85478.1 - 9.6e-05 22.2 8.2 0.00018 21.3 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS85478.1 - 0.00034 20.5 10.9 0.00067 19.6 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 RUS85478.1 - 0.004 17.4 2.8 0.0095 16.2 2.8 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_11 PF17123.5 RUS85478.1 - 0.0043 16.8 7.8 0.0043 16.8 7.8 1.8 2 0 0 2 2 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 RUS85478.1 - 0.011 15.5 8.3 0.02 14.7 8.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 RUS85478.1 - 0.014 15.5 4.9 0.031 14.5 4.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RUS85478.1 - 0.027 14.8 10.9 0.044 14.1 10.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 RUS85478.1 - 0.031 14.3 8.5 0.53 10.4 8.5 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Endonuclease_7 PF02945.15 RUS85478.1 - 0.36 10.8 2.2 0.77 9.7 2.2 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII Zf_RING PF16744.5 RUS85478.1 - 0.8 9.9 4.2 1.8 8.7 4.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3H2C3 PF17122.5 RUS85478.1 - 1.3 9.1 6.9 2.5 8.2 6.9 1.5 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 RUS85478.1 - 1.6 8.9 11.0 3.6 7.8 11.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-3CxxC_2 PF17180.4 RUS85478.1 - 2 9.2 7.1 6.1 7.6 7.1 1.9 1 0 0 1 1 1 0 Zinc-binding domain DUF4515 PF14988.6 RUS85480.1 - 4.5e-19 69.1 36.9 4.5e-19 69.1 36.9 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) PGBA_N PF15436.6 RUS85480.1 - 0.0032 17.1 1.6 0.0055 16.3 1.6 1.4 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA N-terminal Collagen PF01391.18 RUS85480.1 - 0.19 11.5 5.4 0.28 11.0 5.4 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF2584 PF10763.9 RUS85480.1 - 0.31 11.2 4.4 20 5.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2584) VCX_VCY PF15231.6 RUS85480.1 - 0.72 10.5 11.2 0.31 11.7 7.2 2.3 1 1 0 2 2 2 0 Variable charge X/Y family GDA1_CD39 PF01150.17 RUS85481.1 - 1.5e-66 224.8 0.0 3.5e-59 200.5 0.0 2.2 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 RUS85481.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Ppx/GppA phosphatase family RNase_H PF00075.24 RUS85482.1 - 1.9e-14 54.1 0.2 1.9e-14 54.1 0.2 2.6 3 1 0 3 3 3 1 RNase H RVT_3 PF13456.6 RUS85482.1 - 0.00016 21.4 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4864 PF16156.5 RUS85482.1 - 0.11 13.2 0.1 0.26 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Alpha-mann_mid PF09261.11 RUS85482.1 - 2 8.6 6.3 0.69 10.1 0.1 2.8 2 1 0 2 2 2 0 Alpha mannosidase middle domain Ribosomal_S18 PF01084.20 RUS85483.1 - 1.4e-11 44.4 0.0 2.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 ATP-synt_D PF01813.17 RUS85484.1 - 1.3e-75 253.5 2.9 1.3e-75 253.5 2.9 1.7 2 0 0 2 2 2 1 ATP synthase subunit D LRR_6 PF13516.6 RUS85485.1 - 7.9e-18 62.9 11.9 0.001 18.9 0.3 6.6 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 RUS85485.1 - 0.021 15.3 9.4 10 7.1 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 RUS85485.1 - 0.14 12.6 14.6 1.5 9.3 0.5 5.4 4 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS85485.1 - 3.9 7.3 16.1 11 5.9 6.0 4.8 3 2 1 4 4 4 0 Leucine rich repeat adh_short PF00106.25 RUS85486.1 - 1.7e-30 105.9 0.1 2e-29 102.4 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS85486.1 - 7.1e-19 68.3 0.0 2.3e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS85486.1 - 1.5e-07 31.5 0.3 4.3e-07 30.0 0.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS85486.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hpr_kinase_C PF07475.12 RUS85486.1 - 0.042 13.4 0.5 0.071 12.6 0.5 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Polysacc_synt_2 PF02719.15 RUS85486.1 - 0.15 11.1 0.5 2.2 7.3 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein APH PF01636.23 RUS85487.1 - 2.5e-43 148.8 0.0 4.1e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.6 RUS85487.1 - 6.1e-14 52.5 0.0 1.6e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS85487.1 - 2.6e-06 27.9 0.0 1.2e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 RUS85487.1 - 2.2e-05 24.2 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 RUS85487.1 - 9.5e-05 22.1 0.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 RUS85487.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 RUS85487.1 - 0.0027 17.1 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_6 PF13344.6 RUS85487.1 - 0.052 13.7 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF374 PF04028.13 RUS85487.1 - 0.2 11.2 0.2 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Ras PF00071.22 RUS85488.1 - 2e-34 118.5 0.0 2.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85488.1 - 4.2e-17 62.5 0.0 5.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS85488.1 - 8.4e-05 22.6 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS85488.1 - 0.00029 20.5 0.0 0.0086 15.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RUS85488.1 - 0.0023 17.4 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS85488.1 - 0.019 14.8 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 RUS85488.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.8 RUS85489.1 - 0.0032 17.7 8.0 0.1 12.9 2.4 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding WD40 PF00400.32 RUS85489.1 - 0.0054 17.6 0.4 17 6.5 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-met PF12874.7 RUS85489.1 - 0.014 15.8 6.6 1.4 9.5 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS85489.1 - 0.069 13.5 12.3 4.5 7.7 1.5 3.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 RUS85489.1 - 0.11 12.2 3.1 0.26 11.1 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type WD40_like PF17005.5 RUS85489.1 - 0.12 11.7 4.4 0.13 11.6 0.1 2.2 1 1 0 2 2 2 0 WD40-like domain zf-C2H2_4 PF13894.6 RUS85489.1 - 0.37 11.7 3.6 7.7 7.6 0.1 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger HET-S PF17108.5 RUS85489.1 - 0.38 10.5 4.5 1.4 8.7 4.5 2.1 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic Fer4_20 PF14691.6 RUS85490.1 - 0.036 13.8 0.2 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DNA_pol_E_B PF04042.16 RUS85491.1 - 3.6e-53 180.1 2.1 5.5e-53 179.5 2.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 RUS85492.1 - 1.1e-24 86.5 0.0 1.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DUF3849 PF12960.7 RUS85492.1 - 0.035 14.1 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Sld7_C PF18596.1 RUS85492.1 - 0.13 12.4 0.1 6.8 6.9 0.0 2.3 2 1 0 2 2 2 0 Sld7 C-terminal domain Acetyltransf_1 PF00583.25 RUS85493.1 - 1.3e-18 67.4 0.0 2.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RUS85493.1 - 1.5e-11 44.6 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS85493.1 - 4.3e-11 42.9 0.1 1.3e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS85493.1 - 3.8e-07 30.0 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 RUS85493.1 - 2.3e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RUS85493.1 - 0.00054 20.0 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RUS85493.1 - 0.0041 17.8 0.0 0.0069 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RUS85493.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Macoilin PF09726.9 RUS85493.1 - 0.46 9.0 6.9 0.63 8.5 6.9 1.2 1 0 0 1 1 1 0 Macoilin family ubiquitin PF00240.23 RUS85494.1 - 1.2e-34 117.9 0.3 1.2e-34 117.9 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 RUS85494.1 - 6e-25 87.1 5.0 6e-25 87.1 5.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 RUS85494.1 - 1.3e-16 60.2 0.4 1.3e-16 60.2 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS85494.1 - 6.7e-06 26.5 0.4 3.3e-05 24.3 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RUS85494.1 - 0.00038 20.5 0.5 0.00082 19.5 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RUS85494.1 - 0.0047 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 RUS85494.1 - 0.01 16.2 1.4 0.015 15.7 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 RUS85494.1 - 0.012 16.2 0.4 0.017 15.7 0.4 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 RUS85494.1 - 0.13 12.3 3.3 9.5 6.3 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-like domain BTB PF00651.31 RUS85495.1 - 2.2e-20 72.9 0.8 5.7e-20 71.6 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS85495.1 - 1.5e-12 47.5 2.2 1.8e-11 44.0 1.1 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch Carb_bind PF10645.9 RUS85495.1 - 0.033 14.4 0.3 0.11 12.8 0.3 1.9 1 0 0 1 1 1 0 Carbohydrate binding Annexin PF00191.20 RUS85496.1 - 5.2e-32 109.7 0.7 3.9e-08 33.2 0.1 5.5 5 0 0 5 5 5 5 Annexin KIAA1430 PF13879.6 RUS85496.1 - 1.4e-18 67.6 7.3 1.4e-18 67.6 7.3 4.3 3 2 0 4 4 4 1 KIAA1430 homologue Cu-oxidase_2 PF07731.14 RUS85498.1 - 1.9e-33 115.1 9.6 1.4e-29 102.5 0.3 3.3 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 RUS85498.1 - 9.5e-31 107.1 0.0 1.5e-27 96.7 0.0 3.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RUS85498.1 - 6.5e-30 103.6 3.4 2.4e-27 95.3 1.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Nucleoporin_C PF03177.14 RUS85499.1 - 1.7e-27 96.5 16.8 2.1e-26 92.9 10.8 2.6 2 1 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 RUS85499.1 - 4.3e-24 85.1 0.0 7e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like EspA PF03433.13 RUS85500.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein Myb_DNA-binding PF00249.31 RUS85501.1 - 2.9e-16 59.4 0.1 1.4e-10 41.2 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 RUS85501.1 - 3.3e-11 43.8 0.1 3.3e-11 43.8 0.1 2.3 3 0 0 3 3 3 1 ELM2 domain Myb_DNA-bind_6 PF13921.6 RUS85501.1 - 3.2e-06 27.3 0.6 0.00022 21.4 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RUS85501.1 - 1.1e-05 25.2 1.9 0.0055 16.6 0.2 2.6 2 0 0 2 2 2 2 Myb DNA-binding like zf-CpG_bind_C PF12269.8 RUS85501.1 - 0.017 14.9 0.3 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Spectrin PF00435.21 RUS85502.1 - 1.5e-160 523.6 111.9 6.6e-23 81.2 3.5 10.4 10 0 0 10 10 10 10 Spectrin repeat PH_9 PF15410.6 RUS85502.1 - 1.9e-23 83.0 0.1 1.1e-22 80.6 0.1 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RUS85502.1 - 1.3e-14 54.5 0.4 1.9e-13 50.8 0.1 2.9 2 0 0 2 2 2 1 PH domain Mating_N PF12731.7 RUS85502.1 - 0.92 9.6 5.6 8.8 6.5 0.4 4.3 3 0 0 3 3 3 0 Mating-type protein beta 1 PMC2NT PF08066.12 RUS85502.1 - 2.8 8.7 14.2 1.2 9.8 0.2 5.1 4 0 0 4 4 4 0 PMC2NT (NUC016) domain AAA PF00004.29 RUS85503.1 - 1.3e-31 109.7 0.0 1.7e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 RUS85503.1 - 2.7e-09 37.4 0.0 4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RUS85503.1 - 6e-07 29.5 0.2 3.8e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS85503.1 - 1.9e-06 28.3 0.2 0.00097 19.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RUS85503.1 - 3e-05 23.8 0.0 4.8e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS85503.1 - 6.2e-05 23.3 0.4 0.0084 16.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RUS85503.1 - 0.00015 21.2 0.0 0.00028 20.4 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS85503.1 - 0.00015 22.1 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 RUS85503.1 - 0.00017 20.8 0.0 0.0002 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 RUS85503.1 - 0.00019 21.8 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS85503.1 - 0.00024 21.3 0.0 0.00038 20.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RUS85503.1 - 0.00044 20.0 0.1 0.00091 19.0 0.0 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 RUS85503.1 - 0.00048 20.2 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RUS85503.1 - 0.0012 18.8 0.4 0.025 14.5 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.6 RUS85503.1 - 0.0016 19.0 0.0 0.0022 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RUS85503.1 - 0.0023 17.2 0.0 0.0041 16.4 0.0 1.5 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 RUS85503.1 - 0.0026 17.3 0.1 0.027 14.0 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 RUS85503.1 - 0.0036 17.3 0.0 0.0063 16.5 0.0 1.5 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 RUS85503.1 - 0.004 16.6 0.1 0.48 9.8 0.0 2.1 1 1 0 2 2 2 1 Bacterial TniB protein AAA_25 PF13481.6 RUS85503.1 - 0.0075 15.9 1.6 0.042 13.4 0.1 2.0 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 RUS85503.1 - 0.0095 15.9 0.1 0.15 12.0 0.0 2.0 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 RUS85503.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 RUS85503.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 RUS85503.1 - 0.019 14.3 0.1 0.58 9.4 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.11 RUS85503.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS85503.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 RUS85503.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS85503.1 - 0.039 14.5 0.0 0.048 14.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 RUS85503.1 - 0.041 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 RUS85503.1 - 0.044 14.2 0.0 0.064 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS85503.1 - 0.052 13.3 0.1 0.098 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 RUS85503.1 - 0.067 13.1 0.1 0.23 11.3 0.0 1.8 1 1 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 RUS85503.1 - 0.074 12.8 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RUS85503.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AFG1_ATPase PF03969.16 RUS85503.1 - 0.084 11.7 0.0 0.095 11.6 0.0 1.3 1 1 0 1 1 1 0 AFG1-like ATPase Parvo_NS1 PF01057.17 RUS85503.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Adaptin_N PF01602.20 RUS85504.1 - 1.7e-144 482.3 12.9 2e-144 482.0 12.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RUS85504.1 - 5.9e-17 62.2 1.9 4.4e-11 43.1 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AP3D1 PF06375.11 RUS85504.1 - 2.6e-11 44.0 0.1 4.9e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 HEAT PF02985.22 RUS85504.1 - 1.6e-06 27.9 0.5 0.39 11.1 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 RUS85504.1 - 1e-05 25.8 0.1 0.075 13.4 0.0 4.1 3 1 1 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 RUS85504.1 - 0.00015 21.9 2.1 0.94 9.7 0.4 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 RUS85504.1 - 0.00051 20.4 0.6 0.16 12.4 0.2 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 RUS85504.1 - 0.012 15.7 0.9 18 5.6 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RUS85504.1 - 0.021 15.3 2.7 7.3 7.2 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat HSCB_C PF07743.13 RUS85504.1 - 0.22 12.1 4.1 0.3 11.6 0.4 2.7 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Vac14_Fab1_bd PF12755.7 RUS85504.1 - 0.24 12.0 2.5 0.92 10.1 0.1 3.3 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 RUS85504.1 - 0.34 11.0 5.1 21 5.3 0.0 4.5 4 1 1 5 5 5 0 V-ATPase subunit H Rho_Binding PF08912.11 RUS85504.1 - 0.89 10.4 5.5 0.2 12.5 1.5 2.1 2 0 0 2 2 1 0 Rho Binding Peptidase_C54 PF03416.19 RUS85505.1 - 3.4e-30 105.4 0.0 3.4e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 hNIFK_binding PF12196.8 RUS85507.1 - 0.25 10.9 1.2 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK DUF2152 PF10222.9 RUS85512.1 - 1.7e-161 538.7 2.7 2e-134 449.2 2.9 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2152) CCSMST1 PF15013.6 RUS85513.1 - 8.7e-05 22.6 16.2 6.2 7.1 1.1 6.7 1 1 3 4 4 4 4 CCSMST1 family NADH_dh_m_C1 PF15088.6 RUS85513.1 - 0.0058 16.2 33.1 13 5.4 0.2 7.9 1 1 7 8 8 8 7 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial YebO PF13974.6 RUS85513.1 - 0.98 9.5 29.2 20 5.3 0.2 7.3 1 1 7 8 8 8 0 YebO-like protein LRR_8 PF13855.6 RUS85514.1 - 5.6e-52 173.4 58.7 3.6e-11 42.7 3.7 8.9 3 2 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 RUS85514.1 - 1.3e-35 120.8 66.0 3.7e-07 30.4 1.6 11.6 4 3 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS85514.1 - 7e-08 32.2 31.8 0.029 13.9 1.1 6.1 1 1 6 7 7 7 7 Leucine-rich repeat LRR_1 PF00560.33 RUS85514.1 - 5.7e-05 23.1 53.4 4.3 8.3 0.0 15.9 18 1 0 18 18 18 3 Leucine Rich Repeat LRR_5 PF13306.6 RUS85514.1 - 0.00012 22.1 3.8 0.098 12.6 0.3 3.5 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_3 PF07725.12 RUS85514.1 - 6.4 6.8 10.7 40 4.3 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat CSTF_C PF14304.6 RUS85514.1 - 9.7 5.9 9.9 44 3.8 0.0 5.0 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal EF-hand_5 PF13202.6 RUS85515.1 - 2.9e-12 45.5 5.0 4.1e-05 22.9 0.2 3.8 3 1 1 4 4 4 3 EF hand EF-hand_1 PF00036.32 RUS85515.1 - 4.5e-11 41.5 6.5 0.00012 21.3 1.0 3.9 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 RUS85515.1 - 1.1e-09 37.5 8.0 0.00016 21.3 0.6 4.0 2 2 2 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS85515.1 - 4.1e-08 32.9 4.1 0.0018 18.0 0.8 3.8 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 RUS85515.1 - 8.7e-08 32.5 6.9 9e-06 26.1 6.2 3.4 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS85515.1 - 0.0069 16.7 0.4 6.2 7.2 0.0 3.1 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Defensin_propep PF00879.18 RUS85515.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Defensin propeptide Dockerin_1 PF00404.18 RUS85515.1 - 0.88 9.8 6.4 26 5.1 1.2 3.4 2 2 0 2 2 2 0 Dockerin type I domain Band_3_cyto PF07565.13 RUS85516.1 - 1.5 8.5 11.2 0.079 12.7 5.2 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SlyX PF04102.12 RUS85516.1 - 6.5 7.4 13.7 9.2 7.0 0.3 4.1 3 0 0 3 3 3 0 SlyX DUF1361 PF07099.11 RUS85517.1 - 0.22 11.5 0.1 0.35 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) LRR_9 PF14580.6 RUS85520.1 - 1.1e-18 67.4 5.3 6.6e-14 51.8 4.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 RUS85520.1 - 6.3e-13 48.7 24.3 0.00017 21.9 1.1 4.9 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS85520.1 - 1.5e-10 40.7 16.3 2.2e-07 30.6 3.5 3.8 2 1 3 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 RUS85520.1 - 0.0013 18.6 13.2 0.03 14.4 0.2 4.9 5 0 0 5 5 5 2 Leucine Rich repeat Menin PF05053.13 RUS85520.1 - 1.1 7.5 6.2 1.8 6.8 6.2 1.3 1 0 0 1 1 1 0 Menin TNFR_c6 PF00020.18 RUS85521.1 - 2.4e-05 24.6 9.7 4.7e-05 23.7 9.7 1.5 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region DUF3357 PF11837.8 RUS85521.1 - 0.015 15.8 0.0 0.27 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) stn_TNFRSF12A PF12191.8 RUS85521.1 - 0.042 14.1 1.5 0.2 11.9 0.0 2.3 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3318 PF11780.8 RUS85521.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) SIT PF15330.6 RUS85521.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 RUS85521.1 - 0.16 12.9 0.1 1.1 10.2 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 RUS85521.1 - 0.17 11.9 1.2 0.25 11.3 1.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM154 PF15102.6 RUS85521.1 - 0.22 11.4 0.0 0.57 10.1 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family LST1 PF05083.13 RUS85521.1 - 0.39 11.0 2.3 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 LST-1 protein DUF3094 PF11293.8 RUS85521.1 - 0.77 9.5 5.1 11 5.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) polyprenyl_synt PF00348.17 RUS85522.1 - 6.3e-87 290.9 0.0 8e-87 290.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 RUS85522.1 - 0.051 12.9 0.4 0.19 11.1 0.1 2.0 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain RNase_H PF00075.24 RUS85523.1 - 1.1e-14 54.9 3.5 1.2e-14 54.7 0.2 2.4 2 1 0 2 2 2 1 RNase H TFIIA PF03153.13 RUS85523.1 - 1.4e-05 25.3 13.2 1.8e-05 24.9 13.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RVT_3 PF13456.6 RUS85523.1 - 8.6e-05 22.3 0.4 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like PPP4R2 PF09184.11 RUS85523.1 - 0.00068 19.3 9.7 0.00092 18.9 9.7 1.3 1 0 0 1 1 1 1 PPP4R2 SDA1 PF05285.12 RUS85523.1 - 0.026 14.0 15.3 0.038 13.4 15.3 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 RUS85523.1 - 1 8.6 33.3 2.1 7.6 33.3 1.6 1 0 0 1 1 1 0 NOA36 protein Trypsin_2 PF13365.6 RUS85524.1 - 0.00033 21.6 0.1 0.0014 19.6 0.1 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain VWC PF00093.18 RUS85524.1 - 0.0013 19.0 12.4 0.0013 19.0 12.4 2.2 2 0 0 2 2 2 1 von Willebrand factor type C domain Transpos_assoc PF13963.6 RUS85524.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase-associated domain RUN PF02759.19 RUS85525.1 - 1.5e-32 112.4 0.1 3.2e-32 111.3 0.1 1.6 1 0 0 1 1 1 1 RUN domain DUF3964 PF13107.6 RUS85525.1 - 0.0053 17.1 0.3 0.021 15.2 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3964) TSC22 PF01166.18 RUS85525.1 - 0.78 10.1 6.2 1.6 9.1 0.1 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Snapin_Pallidin PF14712.6 RUS85525.1 - 0.86 10.1 11.9 2.5 8.6 3.9 3.1 2 1 0 2 2 2 0 Snapin/Pallidin IFT81_CH PF18383.1 RUS85525.1 - 1.6 9.0 5.4 0.33 11.2 0.4 2.5 4 0 0 4 4 4 0 Intraflagellar transport 81 calponin homology domain BAAT_C PF08840.11 RUS85526.1 - 3.3e-47 161.2 0.0 5.5e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.14 RUS85526.1 - 1.6e-25 89.6 0.0 2.5e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.18 RUS85526.1 - 6e-05 22.7 0.1 0.032 13.8 0.0 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family ARS2 PF04959.13 RUS85528.1 - 0.05 14.0 5.7 0.077 13.4 5.7 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 LZ_Tnp_IS481 PF13011.6 RUS85528.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.7 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 GET2 PF08690.10 RUS85528.1 - 0.81 9.3 3.5 0.58 9.8 1.2 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 Pkinase PF00069.25 RUS85529.1 - 2.2e-21 76.4 0.0 3.1e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85529.1 - 1.2e-15 57.5 0.0 1.8e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RUS85529.1 - 0.85 10.1 4.4 0.94 9.9 0.2 3.0 3 0 0 3 3 3 0 HEAT repeat Adaptin_N PF01602.20 RUS85531.1 - 5.7e-145 483.8 2.9 6.9e-145 483.6 2.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 RUS85531.1 - 8.2e-40 135.5 0.0 1.9e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 RUS85531.1 - 4.2e-10 39.9 0.1 1e-09 38.7 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 RUS85531.1 - 6.1e-05 23.3 0.6 0.06 13.7 0.1 3.9 2 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 RUS85531.1 - 0.001 19.1 0.3 0.029 14.4 0.0 2.8 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RUS85531.1 - 0.0025 17.6 3.2 0.061 13.1 0.7 3.4 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis B2-adapt-app_C PF09066.10 RUS85531.1 - 0.017 15.2 0.1 0.049 13.7 0.1 1.9 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Sulfotransfer_3 PF13469.6 RUS85532.1 - 2.9e-09 37.6 0.0 6.5e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS85532.1 - 5.7e-07 29.3 0.2 1.4e-06 28.0 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 RUS85533.1 - 1.6e-05 24.5 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85533.1 - 0.0013 19.2 0.0 0.0026 18.2 0.0 1.5 1 1 1 2 2 2 1 Sulfotransferase family Ins145_P3_rec PF08709.11 RUS85534.1 - 1.1e-86 289.5 0.2 2.8e-86 288.1 0.2 1.8 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 RUS85534.1 - 9.5e-70 234.2 0.0 5.4e-68 228.5 0.0 2.8 2 0 0 2 2 2 1 MIR domain RYDR_ITPR PF01365.21 RUS85534.1 - 1.8e-63 213.7 27.9 7e-58 195.4 1.4 4.9 4 1 0 4 4 4 2 RIH domain RIH_assoc PF08454.11 RUS85534.1 - 3e-33 113.7 4.8 3e-33 113.7 4.8 5.3 6 0 0 6 6 6 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RUS85534.1 - 9.2e-16 57.8 14.2 1.8e-15 56.8 14.2 1.5 1 0 0 1 1 1 1 Ion transport protein PEX11 PF05648.14 RUS85534.1 - 1.2 8.6 4.1 1.2 8.5 0.1 2.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Sec2p PF06428.11 RUS85534.1 - 8.4 6.4 10.9 3.8 7.6 5.0 3.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Hum_adeno_E3A PF05393.11 RUS85535.1 - 0.14 12.1 0.4 0.73 9.8 0.2 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Sulfotransfer_1 PF00685.27 RUS85537.1 - 8.2e-14 51.7 0.1 2.7e-13 50.0 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85537.1 - 4e-08 33.9 0.4 1e-06 29.3 0.4 2.7 1 1 0 1 1 1 1 Sulfotransferase family DUF773 PF05600.12 RUS85537.1 - 0.013 14.3 0.4 0.019 13.7 0.4 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 RhoGAP PF00620.27 RUS85538.1 - 3.1e-35 121.2 0.1 6.1e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 RUS85538.1 - 7.4e-26 90.8 0.1 1.3e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 START domain Lig_chan PF00060.26 RUS85539.1 - 8.4e-60 200.9 0.2 1.6e-59 200.1 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS85539.1 - 2.8e-39 133.9 0.0 6.8e-39 132.6 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RUS85539.1 - 4.9e-35 121.3 0.9 7.6e-35 120.6 0.9 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RUS85539.1 - 2.1e-22 79.6 0.0 3.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 RUS85539.1 - 0.14 11.8 0.2 10 5.7 0.1 2.5 3 0 0 3 3 3 0 Periplasmic binding protein DPM3 PF08285.11 RUS85540.1 - 0.074 13.2 0.5 0.1 12.8 0.1 1.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) adh_short PF00106.25 RUS85541.1 - 3e-29 101.9 0.3 4.4e-29 101.3 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS85541.1 - 1e-18 67.8 0.1 1.7e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS85541.1 - 2.2e-06 27.7 0.1 3.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RUS85541.1 - 0.056 12.9 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sec7 PF01369.20 RUS85542.1 - 1e-33 116.6 0.0 1.4e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 RUS85542.1 - 1.5e-06 28.0 1.1 3.5e-06 26.8 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS85542.1 - 0.0003 20.6 0.4 0.00066 19.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain Cadherin PF00028.17 RUS85545.1 - 2.1e-91 300.5 0.9 2.7e-17 63.0 0.1 7.6 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS85545.1 - 5e-17 61.5 0.0 1.1e-12 47.6 0.0 4.9 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 RUS85545.1 - 4.2e-05 23.5 3.6 0.43 10.6 0.1 5.8 6 1 0 6 6 6 1 Cadherin-like SKG6 PF08693.10 RUS85545.1 - 8.2e-05 21.9 0.8 0.0002 20.7 0.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Hamartin PF04388.12 RUS85545.1 - 0.031 13.0 7.0 0.052 12.2 7.0 1.3 1 0 0 1 1 1 0 Hamartin protein LRR_6 PF13516.6 RUS85547.1 - 7e-13 47.5 16.0 0.00069 19.5 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich repeat EF-hand_7 PF13499.6 RUS85547.1 - 5.6e-11 42.7 0.2 1.4e-10 41.5 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS85547.1 - 1.1e-07 31.6 0.1 4.8e-07 29.5 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 RUS85547.1 - 2.5e-05 24.5 9.3 0.039 14.4 0.6 5.0 2 2 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS85547.1 - 7.6e-05 22.7 0.8 20 6.2 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 RUS85547.1 - 0.00024 20.8 9.8 0.14 12.0 1.7 4.9 3 3 1 4 4 4 2 Leucine rich repeat DNA_pol_phi PF04931.13 RUS85547.1 - 0.013 13.6 41.8 0.024 12.8 41.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 RUS85547.1 - 3.4 7.6 31.3 5.2 6.9 31.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad60-SLD PF11976.8 RUS85548.1 - 2.1e-21 75.5 0.0 3.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RUS85548.1 - 1.2e-09 37.7 0.1 3.4e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family MBT PF02820.18 RUS85549.1 - 5.7e-90 295.7 6.0 1.6e-27 95.7 0.2 4.3 4 0 0 4 4 4 4 mbt repeat tRNA-synt_His PF13393.6 RUS85550.1 - 2e-38 132.4 0.0 4e-38 131.4 0.0 1.5 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 RUS85550.1 - 2e-11 43.9 0.1 3.6e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 RUS85550.1 - 0.0018 17.4 0.0 0.0065 15.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 RUS85550.1 - 0.008 16.3 0.2 0.028 14.6 0.2 2.0 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 RUS85550.1 - 0.011 15.3 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 RUS85550.1 - 0.044 13.8 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) TENA_THI-4 PF03070.16 RUS85550.1 - 0.065 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 TENA/THI-4/PQQC family Methyltransf_11 PF08241.12 RUS85551.1 - 3.3e-12 46.9 0.0 1.6e-10 41.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS85551.1 - 4e-09 37.1 0.0 0.00033 21.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 RUS85551.1 - 3.2e-07 31.0 0.0 1.4e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS85551.1 - 3.7e-05 23.6 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RUS85551.1 - 0.00027 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 RUS85551.1 - 0.16 12.6 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) FH2 PF02181.23 RUS85552.1 - 7.5e-48 163.5 0.8 2.1e-30 106.1 0.6 2.4 1 1 1 2 2 2 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 RUS85552.1 - 1.2e-18 67.4 3.5 3.1e-18 66.1 3.5 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RUS85552.1 - 1.5e-13 50.8 0.0 4.5e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain TolA_bind_tri PF16331.5 RUS85552.1 - 0.095 12.8 0.1 0.37 10.9 0.1 2.1 1 0 0 1 1 1 0 TolA binding protein trimerisation W2 PF02020.18 RUS85553.1 - 6.6e-16 58.2 0.0 6.6e-16 58.2 0.0 3.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 RUS85553.1 - 1.9e-11 43.2 12.6 2.8e-05 23.6 1.3 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RUS85553.1 - 2e-07 29.6 1.6 3.4e-07 28.8 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 RUS85553.1 - 5.4e-07 29.4 0.0 9.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RUS85553.1 - 0.00052 20.4 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 RUS85553.1 - 0.0042 16.1 0.1 0.01 14.8 0.1 1.6 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 RUS85553.1 - 0.071 12.9 13.5 1.3 8.9 0.7 4.2 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 RUS85553.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase F-box-like PF12937.7 RUS85554.1 - 5.2e-08 32.7 0.2 2.7e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS85554.1 - 2.9e-05 23.8 0.0 0.00013 21.7 0.0 2.2 1 0 0 1 1 1 1 F-box domain Glyco_transf_92 PF01697.27 RUS85555.1 - 4.3e-31 108.5 0.0 4.3e-31 108.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS85555.1 - 7.3e-05 23.2 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Plasmodium_HRP PF05403.11 RUS85555.1 - 0.21 11.4 1.9 1.2 8.9 1.8 2.0 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) Exo_endo_phos PF03372.23 RUS85556.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Nucleocapsid-N PF11030.8 RUS85557.1 - 1.7 8.5 6.2 3.7 7.5 2.1 2.2 2 0 0 2 2 2 0 Nucleocapsid protein N Fasciclin PF02469.22 RUS85558.1 - 1.3e-37 128.9 0.7 7e-27 94.2 0.0 3.3 2 1 1 3 3 3 3 Fasciclin domain DUF1661 PF07877.11 RUS85558.1 - 0.0088 15.7 0.1 67 3.3 0.0 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1661) DUF3693 PF12472.8 RUS85558.1 - 0.28 10.9 11.9 26 4.6 0.1 5.0 1 1 4 5 5 5 0 Phage related protein PGK PF00162.19 RUS85559.1 - 1.5e-151 504.7 0.3 1.7e-151 504.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 RUS85559.1 - 0.0034 17.4 0.0 0.065 13.3 0.0 2.9 3 1 0 3 3 3 1 PA domain DUF1771 PF08590.10 RUS85560.1 - 5.1e-09 36.4 10.7 7.5e-09 35.8 10.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Glyoxalase_6 PF18029.1 RUS85560.1 - 0.13 13.1 2.2 0.29 12.0 2.2 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain AAA_33 PF13671.6 RUS85561.1 - 1.1e-06 28.8 0.3 2.5e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Sulfotransfer_1 PF00685.27 RUS85562.1 - 9.1e-11 41.7 0.1 1.4e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85562.1 - 1.1e-09 39.0 0.3 1.7e-09 38.4 0.3 1.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS85562.1 - 0.016 15.1 0.4 0.033 14.1 0.2 1.6 1 1 0 1 1 1 0 Sulfotransferase family DUF4834 PF16118.5 RUS85562.1 - 0.085 13.8 0.0 0.18 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Zip PF02535.22 RUS85562.1 - 0.15 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 RUS85562.1 - 0.73 7.9 5.6 1 7.4 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi NuDC PF16273.5 RUS85562.1 - 2.3 8.8 11.9 4.8 7.8 11.9 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain Sulfotransfer_1 PF00685.27 RUS85563.1 - 2.7e-12 46.7 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85563.1 - 2.1e-07 31.5 0.0 0.012 16.0 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family TauD PF02668.16 RUS85566.1 - 2.4e-08 34.1 0.0 2.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 RUS85566.1 - 0.0014 17.9 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 CsiD VHS PF00790.19 RUS85567.1 - 1.6e-37 128.5 1.4 1.3e-35 122.3 0.0 2.6 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 RUS85567.1 - 1.6e-26 92.8 0.1 1.6e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 RUS85567.1 - 1.4e-19 69.4 5.5 3.5e-19 68.1 5.5 1.7 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 RUS85567.1 - 2.5e-15 56.5 0.8 2.5e-15 56.5 0.8 2.4 2 0 0 2 2 2 1 GAT domain Csm1_N PF18504.1 RUS85567.1 - 0.02 15.2 2.6 0.046 14.1 2.6 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF2096 PF09869.9 RUS85567.1 - 0.055 13.5 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Cauli_AT PF03233.13 RUS85567.1 - 1.9 8.4 5.5 3.5 7.5 2.9 2.1 2 0 0 2 2 2 0 Aphid transmission protein DDE_1 PF03184.19 RUS85568.1 - 3.4e-16 59.4 0.0 7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 RUS85568.1 - 1.5e-05 24.7 0.1 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Vitellogenin_N PF01347.22 RUS85568.1 - 0.0068 14.9 1.3 0.011 14.2 1.3 1.3 1 0 0 1 1 1 1 Lipoprotein amino terminal region HTH_Tnp_ISL3 PF13542.6 RUS85568.1 - 0.035 13.5 0.1 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 LUC7 PF03194.15 RUS85569.1 - 7.6e-79 264.9 8.3 7.6e-79 264.9 8.3 1.9 2 0 0 2 2 2 1 LUC7 N_terminus SPATIAL PF15256.6 RUS85570.1 - 2.3e-14 54.2 0.1 2.7e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 SPATIAL SPATIAL PF15256.6 RUS85571.1 - 9.1e-32 111.0 0.0 1.7e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 SPATIAL tRNA_m1G_MT PF01746.21 RUS85572.1 - 3.6e-31 108.4 0.0 6.4e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Vitellogenin_N PF01347.22 RUS85573.1 - 1e-41 143.1 0.5 4.7e-41 140.9 0.5 1.8 1 1 0 1 1 1 1 Lipoprotein amino terminal region zf-3CxxC_2 PF17180.4 RUS85574.1 - 9.7e-26 90.3 9.3 9.7e-26 90.3 9.3 2.4 3 0 0 3 3 3 1 Zinc-binding domain zf-CCHC_2 PF13696.6 RUS85574.1 - 1.1e-10 41.1 3.6 1.1e-10 41.1 3.6 3.1 3 0 0 3 3 3 1 Zinc knuckle zf-3CxxC PF13695.6 RUS85574.1 - 0.019 15.4 17.7 0.13 12.7 15.1 3.2 2 1 0 2 2 2 0 Zinc-binding domain zf-CHY PF05495.12 RUS85574.1 - 0.62 10.6 11.7 5.3 7.6 2.0 2.8 2 0 0 2 2 2 0 CHY zinc finger RHD_DNA_bind PF00554.22 RUS85575.1 - 4.1e-52 176.6 0.0 6.4e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 RUS85575.1 - 1.3e-38 131.1 0.1 2.5e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Ank_2 PF12796.7 RUS85575.1 - 1.4e-23 83.3 7.7 2.8e-11 43.8 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS85575.1 - 1.1e-22 80.1 7.0 2.6e-08 34.2 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS85575.1 - 1.7e-19 67.8 7.1 0.013 16.0 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RUS85575.1 - 1.1e-18 66.7 13.6 0.0013 19.1 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS85575.1 - 3.5e-15 55.9 9.4 0.00037 20.7 0.1 4.7 2 2 1 4 4 4 3 Ankyrin repeats (many copies) IPK PF03770.16 RUS85576.1 - 7.7e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Mito_carr PF00153.27 RUS85577.1 - 3e-56 187.3 1.8 1.7e-17 63.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 RUS85578.1 - 1.1e-53 178.0 32.5 1.3e-06 29.0 0.2 10.8 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.11 RUS85578.1 - 3.8e-38 130.6 0.0 6.4e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 RUS85578.1 - 9.4e-14 51.5 5.5 0.047 14.0 0.0 7.7 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RUS85578.1 - 0.00011 21.1 1.8 0.58 8.8 0.1 4.9 4 2 0 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 RUS85578.1 - 0.028 13.7 0.8 4.1 6.7 0.0 3.2 2 1 1 3 3 3 0 WD40-like domain CIDR1_gamma PF18562.1 RUS85578.1 - 0.042 13.9 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Cysteine-Rich Interdomain Region 1 gamma Ge1_WD40 PF16529.5 RUS85578.1 - 0.054 12.4 9.6 0.78 8.6 0.1 5.0 3 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 RUS85578.1 - 0.08 12.3 0.1 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region CTP_transf_like PF01467.26 RUS85579.1 - 1e-45 155.5 0.2 8.9e-28 97.3 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 RUS85579.1 - 0.0043 16.9 3.7 2.1 8.2 0.1 3.3 3 0 0 3 3 3 2 FAD synthetase COQ7 PF03232.13 RUS85580.1 - 7.1e-79 263.5 0.1 8.8e-79 263.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 RUS85580.1 - 0.0025 18.2 0.5 0.0077 16.6 0.5 1.9 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 RUS85580.1 - 0.0097 16.1 0.0 0.053 13.7 0.0 2.1 1 1 0 1 1 1 1 Ferritin-like domain DUF4677 PF15726.5 RUS85580.1 - 0.017 15.3 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) DUF4145 PF13643.6 RUS85580.1 - 0.056 13.6 2.6 2.6 8.2 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) DUF3216 PF11505.8 RUS85580.1 - 0.064 13.5 0.7 0.44 10.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3216) DUF3387 PF11867.8 RUS85580.1 - 0.095 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) SOCS_box PF07525.16 RUS85581.1 - 1.5e-05 25.3 2.2 1.5e-05 25.3 2.2 2.2 2 0 0 2 2 2 1 SOCS box AAA_33 PF13671.6 RUS85583.1 - 5.4e-23 81.7 0.0 5.4e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 RUS85583.1 - 5.3e-11 42.7 0.0 5.3e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 SPRY domain AAA_18 PF13238.6 RUS85583.1 - 0.00022 21.7 0.1 0.00074 20.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS85583.1 - 0.2 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 RUS85583.1 - 9.9 6.0 62.9 0.043 13.8 36.0 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Use1 PF09753.9 RUS85584.1 - 1.3 8.7 6.8 2.1 8.0 6.8 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 TFIID-18kDa PF02269.16 RUS85585.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit RVT_1 PF00078.27 RUS85586.1 - 4.8e-18 65.5 0.0 7.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CS PF04969.16 RUS85588.1 - 9.7e-18 65.0 0.3 2.4e-17 63.7 0.3 1.7 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 RUS85588.1 - 3.8e-13 49.2 0.2 1.2e-12 47.6 0.2 1.9 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. NuDC PF16273.5 RUS85588.1 - 9.7e-06 26.0 24.4 9.7e-06 26.0 24.4 3.5 2 2 1 3 3 3 1 Nuclear distribution C domain CRT10 PF08728.10 RUS85588.1 - 0.048 11.8 4.0 0.046 11.9 4.0 1.2 1 0 0 1 1 1 0 CRT10 PET10 PF17316.2 RUS85588.1 - 0.46 10.0 4.5 0.77 9.2 4.5 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 ORC3_N PF07034.11 RUS85590.1 - 4.5e-86 289.0 0.1 8.6e-86 288.0 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 RUS85590.1 - 7.6e-34 116.8 0.0 3.1e-33 114.8 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal WD40 PF00400.32 RUS85591.1 - 8.1e-28 96.1 15.9 2.8e-07 31.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 RUS85591.1 - 1.3e-25 89.5 0.3 1.8e-24 85.8 0.1 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 RUS85591.1 - 3.1e-05 24.2 2.6 0.04 14.2 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Forkhead PF00250.18 RUS85592.1 - 4.5e-26 90.9 0.1 1e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FOXO-TAD PF16676.5 RUS85592.1 - 6.5e-07 29.7 4.2 6.5e-07 29.7 4.2 2.2 2 0 0 2 2 2 1 Transactivation domain of FOXO protein family SPO22 PF08631.10 RUS85593.1 - 0.00018 21.1 1.0 0.00024 20.7 1.0 1.2 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like I-set PF07679.16 RUS85594.1 - 1.6e-15 56.9 0.0 2.8e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS85594.1 - 1.7e-15 57.4 0.4 8.7e-09 35.9 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS85594.1 - 1.3e-10 41.4 0.4 2.1e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS85594.1 - 1.6e-08 34.6 0.2 0.0026 17.9 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS85594.1 - 8.2e-05 22.7 1.2 0.16 12.2 0.0 3.2 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS85594.1 - 0.016 14.7 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain C2-set_2 PF08205.12 RUS85594.1 - 0.019 15.0 0.1 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ank_2 PF12796.7 RUS85596.1 - 1.7e-18 67.0 0.7 8.2e-11 42.3 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS85596.1 - 2.2e-16 60.0 0.8 2.8e-06 27.8 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS85596.1 - 6.7e-14 51.6 5.2 0.00059 20.2 0.1 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 RUS85596.1 - 1.6e-12 46.4 0.4 0.01 16.3 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS85596.1 - 2.1e-12 47.0 1.7 4.4e-08 33.2 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HrpB1_HrpK PF09613.10 RUS85596.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Pkinase PF00069.25 RUS85597.1 - 3.6e-18 65.9 0.1 4.1e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85597.1 - 1.1e-13 51.0 0.0 1.3e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase H_lectin PF09458.10 RUS85598.1 - 7e-06 26.1 0.1 1.1e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 H-type lectin domain Calcipressin PF04847.12 RUS85599.1 - 2.2e-41 141.7 0.0 3.1e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Calcipressin NDUF_B8 PF05821.11 RUS85601.1 - 2e-40 138.5 0.5 2.8e-40 138.1 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Ribosomal_S9 PF00380.19 RUS85602.1 - 4.5e-35 120.8 0.0 1.2e-34 119.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UPF0220 PF05255.11 RUS85603.1 - 5.9e-45 152.8 1.8 6.5e-45 152.6 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5357 PF17310.2 RUS85603.1 - 0.53 8.8 3.4 7 5.1 0.2 2.1 1 1 0 2 2 2 0 Family of unknown function (DUF5357) DHHC PF01529.20 RUS85603.1 - 0.78 9.8 3.8 0.98 9.5 1.4 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Yip1 PF04893.17 RUS85604.1 - 3.4e-09 36.6 16.2 4.6e-09 36.2 16.2 1.2 1 0 0 1 1 1 1 Yip1 domain LRR_8 PF13855.6 RUS85605.1 - 2.8e-35 119.8 28.4 3.5e-13 49.1 1.5 4.0 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 RUS85605.1 - 3.8e-14 52.6 13.6 6.7e-05 23.2 0.1 4.7 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS85605.1 - 3.4e-09 36.0 11.3 0.024 15.1 0.6 6.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_5 PF13306.6 RUS85605.1 - 2.7e-05 24.1 0.0 0.019 14.9 0.0 2.4 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 RUS85605.1 - 0.00016 22.2 0.0 0.00079 20.0 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS85605.1 - 0.0012 18.9 0.0 0.0084 16.2 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain LRR_9 PF14580.6 RUS85605.1 - 0.0032 17.0 1.1 0.014 14.9 1.1 1.9 1 1 0 1 1 1 1 Leucine-rich repeat TPKR_C2 PF16920.5 RUS85605.1 - 0.013 15.6 1.6 0.039 14.1 1.6 1.9 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain Ly49 PF08391.10 RUS85605.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ig PF00047.25 RUS85605.1 - 0.021 15.0 0.1 0.44 10.7 0.1 2.8 1 1 0 1 1 1 0 Immunoglobulin domain LRR_6 PF13516.6 RUS85605.1 - 0.023 14.7 18.0 0.81 9.9 1.2 5.3 5 0 0 5 5 5 0 Leucine Rich repeat Shisa PF13908.6 RUS85605.1 - 0.026 14.8 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 RUS85605.1 - 0.035 15.0 0.1 0.071 14.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Miga PF10265.9 RUS85605.1 - 0.054 12.5 0.4 0.083 11.8 0.4 1.2 1 0 0 1 1 1 0 Mitoguardin LapA_dom PF06305.11 RUS85605.1 - 0.062 13.1 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 RUS85605.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4051 PF13260.6 RUS85605.1 - 0.14 12.0 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) V-set PF07686.17 RUS85605.1 - 0.15 12.2 0.3 25 5.1 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin V-set domain ECSCR PF15820.5 RUS85605.1 - 0.18 11.7 0.6 0.34 10.8 0.6 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LRR_3 PF07725.12 RUS85605.1 - 8.5 6.4 5.6 3.3 7.7 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich Repeat Somatomedin_B PF01033.17 RUS85608.1 - 5.1e-06 26.8 10.8 5.1e-06 26.8 10.8 2.4 2 0 0 2 2 2 1 Somatomedin B domain Nucleoporin_FG PF13634.6 RUS85608.1 - 5.1 8.0 37.8 0.028 15.2 10.6 4.4 3 1 0 3 3 3 0 Nucleoporin FG repeat region 7tm_1 PF00001.21 RUS85610.1 - 6.1e-06 25.8 6.5 6.1e-06 25.8 6.5 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS85611.1 - 0.00012 21.5 2.6 0.00018 20.9 2.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PNP_UDP_1 PF01048.20 RUS85612.1 - 4.9e-45 153.6 0.0 5.6e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NAD_binding_10 PF13460.6 RUS85612.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SPICE PF15678.5 RUS85613.1 - 3.5e-74 250.6 30.3 3.5e-74 250.6 30.3 3.9 3 1 0 3 3 3 1 Centriole duplication and mitotic chromosome congression SATase_N PF06426.14 RUS85613.1 - 0.23 11.9 5.5 0.46 10.9 1.9 3.2 3 0 0 3 3 3 0 Serine acetyltransferase, N-terminal Coleoptericin PF06286.11 RUS85613.1 - 0.29 11.3 1.9 0.81 9.8 0.8 2.3 1 1 1 2 2 2 0 Coleoptericin SNF2_N PF00176.23 RUS85614.1 - 1.9e-71 240.6 1.3 1.9e-71 240.6 1.3 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.13 RUS85614.1 - 1.8e-19 69.8 14.1 1.8e-19 69.8 14.1 4.5 3 0 0 3 3 3 1 HSA Helicase_C PF00271.31 RUS85614.1 - 1.9e-19 70.0 0.1 9.8e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.6 RUS85614.1 - 3.5e-18 66.0 7.3 3.5e-18 66.0 7.3 5.8 6 1 0 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 RUS85614.1 - 2.4e-17 62.7 0.4 1.9e-16 59.9 0.7 2.4 2 0 0 2 2 2 1 Bromodomain BRK PF07533.16 RUS85614.1 - 4.6e-17 61.4 1.2 1.2e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 BRK domain QLQ PF08880.11 RUS85614.1 - 6.9e-12 44.9 0.9 6.9e-12 44.9 0.9 2.1 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 RUS85614.1 - 1.6e-11 44.5 0.0 1.6e-11 44.5 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RUS85614.1 - 0.00033 20.5 0.5 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Brix PF04427.18 RUS85615.1 - 1e-40 139.9 0.1 1.7e-40 139.2 0.1 1.4 1 0 0 1 1 1 1 Brix domain Actin PF00022.19 RUS85616.1 - 3.9e-150 500.0 0.0 1.3e-149 498.3 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 RUS85617.1 - 2.6e-150 500.6 0.0 8.6e-150 498.9 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 RUS85619.1 - 1.3e-109 366.6 0.0 5.9e-109 364.4 0.0 1.7 1 1 0 1 1 1 1 Actin His_Phos_1 PF00300.22 RUS85620.1 - 2.7e-22 79.4 0.0 1.1e-12 48.1 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Complex1_LYR PF05347.15 RUS85621.1 - 8.8e-13 48.1 0.0 9.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS85621.1 - 4.7e-06 27.3 0.2 4.7e-06 27.3 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Baculo_PEP_C PF04513.12 RUS85622.1 - 3.9e-08 33.4 17.4 0.0015 18.6 8.5 2.8 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 RUS85622.1 - 9.6e-05 22.2 27.5 0.013 15.3 17.5 2.2 1 1 1 2 2 2 2 Bacterial collagen, middle region VPS13_C PF16909.5 RUS85622.1 - 0.00015 21.6 29.0 0.28 10.9 6.9 3.4 1 1 2 3 3 3 3 Vacuolar-sorting-associated 13 protein C-terminal Apolipoprotein PF01442.18 RUS85622.1 - 0.28 11.0 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 RUS85623.1 - 5.8e-14 51.8 24.0 3.2e-13 49.4 6.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS85623.1 - 0.0001 21.3 1.7 0.0001 21.3 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5504 PF17608.2 RUS85623.1 - 2 8.5 5.3 1.2 9.2 1.8 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5504) CxxCxxCC PF03692.15 RUS85624.1 - 1.3e-06 29.0 13.8 0.085 13.6 2.9 3.7 1 1 2 3 3 3 3 Putative zinc- or iron-chelating domain DUF3215 PF11503.8 RUS85624.1 - 0.00056 19.7 0.7 11 5.9 0.0 3.8 1 1 3 4 4 4 2 Protein of unknown function (DUF3215) ADAM17_MPD PF16698.5 RUS85624.1 - 0.0056 17.0 21.1 0.35 11.3 2.4 3.3 1 1 2 3 3 3 3 Membrane-proximal domain, switch, for ADAM17 WD40_3 PF15911.5 RUS85624.1 - 0.011 15.7 4.6 1.6 8.8 0.3 3.2 2 1 2 4 4 4 0 WD domain, G-beta repeat AIB PF15334.6 RUS85624.1 - 0.45 9.8 6.0 0.42 9.9 2.6 1.8 1 1 1 2 2 2 0 Aurora kinase A and ninein interacting protein DUF1391 PF07151.12 RUS85624.1 - 3.9 7.4 12.5 53 3.7 0.5 5.0 1 1 4 6 6 6 0 Protein of unknown function (DUF1391) cNMP_binding PF00027.29 RUS85625.1 - 1.2e-11 44.5 0.0 4.6e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain NAD_binding_4 PF07993.12 RUS85625.1 - 0.027 13.7 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein SOAR PF16533.5 RUS85625.1 - 0.95 9.5 4.8 0.21 11.6 1.4 1.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region RMF PF04957.12 RUS85626.1 - 0.00014 22.0 6.6 8 6.8 0.9 5.2 1 1 3 4 4 4 2 Ribosome modulation factor Na_H_antiport_2 PF13726.6 RUS85626.1 - 0.00086 19.4 0.0 1.7 8.8 0.0 2.9 1 1 2 3 3 3 3 Na+-H+ antiporter family DUF3991 PF13154.6 RUS85626.1 - 0.0022 18.3 2.0 6.1 7.3 0.1 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF3991) DUF3219 PF11514.8 RUS85626.1 - 0.037 14.0 0.1 42 4.2 0.0 3.5 1 1 4 5 5 5 0 Protein of unknown function (DUF3219) Regulator_TrmB PF11495.8 RUS85626.1 - 0.18 10.9 0.0 12 5.0 0.0 2.4 1 1 1 2 2 2 0 Archaeal transcriptional regulator TrmB Beta_helix_2 PF18835.1 RUS85626.1 - 0.36 10.6 1.1 63 3.4 0.1 3.2 1 1 4 5 5 5 0 Beta helix repeat of Inulin fructotransferase ABC_trans_N PF14510.6 RUS85626.1 - 1.3 9.7 5.4 1.2e+02 3.4 0.1 3.6 1 1 3 5 5 5 0 ABC-transporter N-terminal Phospholip_A2_2 PF05826.12 RUS85628.1 - 1.5e-31 108.5 2.8 3e-31 107.5 2.8 1.5 1 0 0 1 1 1 1 Phospholipase A2 FerA PF08165.11 RUS85628.1 - 0.019 14.9 0.0 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 FerA (NUC095) domain Phospholip_A2_1 PF00068.19 RUS85628.1 - 0.041 14.3 8.1 1.9 9.0 8.1 2.4 1 1 0 1 1 1 0 Phospholipase A2 Fasciclin PF02469.22 RUS85629.1 - 4.6e-19 68.9 0.0 6.9e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 RUS85630.1 - 6.5e-61 204.2 0.0 4e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 RUS85632.1 - 8.5e-61 203.8 0.1 1.8e-34 118.7 0.0 2.6 2 0 0 2 2 2 2 Fasciclin domain Ank_2 PF12796.7 RUS85632.1 - 3.1e-33 114.2 0.1 5.7e-12 46.0 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS85632.1 - 1.6e-24 85.9 2.6 1.5e-07 31.8 0.3 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS85632.1 - 1.2e-19 70.1 1.3 5.5e-05 23.4 0.0 6.1 2 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS85632.1 - 1.6e-18 64.9 1.8 0.001 19.3 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 RUS85632.1 - 1.5e-13 50.5 1.6 0.0017 18.7 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat RRN3 PF05327.11 RUS85632.1 - 0.0028 16.3 8.7 0.0028 16.3 8.7 1.9 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 RUS85632.1 - 0.0038 16.7 8.7 0.0038 16.7 8.7 3.1 3 1 0 3 3 2 1 SDA1 Pes-10 PF07149.11 RUS85632.1 - 0.087 11.9 7.1 0.18 10.8 7.1 1.4 1 0 0 1 1 1 0 Pes-10 Mpp10 PF04006.12 RUS85632.1 - 0.3 9.5 26.7 0.018 13.5 6.3 2.9 3 0 0 3 3 3 0 Mpp10 protein DNA_pol_phi PF04931.13 RUS85632.1 - 0.31 9.1 30.7 0.57 8.2 30.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi BSMAP PF12280.8 RUS85632.1 - 2.2 8.5 0.0 2.2 8.5 0.0 3.0 2 1 0 2 2 1 0 Brain specific membrane anchored protein NOA36 PF06524.12 RUS85632.1 - 4.1 6.6 31.7 11 5.2 31.7 1.7 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RUS85632.1 - 9.6 6.0 21.6 0.098 12.5 13.0 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 RUS85633.1 - 0.29 10.5 49.3 0.39 10.1 49.3 1.1 1 0 0 1 1 1 0 SDA1 GAS PF13851.6 RUS85634.1 - 0.00016 21.1 26.5 0.00016 21.1 26.5 3.3 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 RUS85634.1 - 0.052 12.8 51.5 1.1 8.4 48.9 3.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF948 PF06103.11 RUS85634.1 - 0.86 9.9 17.3 0.52 10.6 2.1 3.7 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 RUS85634.1 - 0.89 10.2 24.5 7.4 7.2 8.5 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal E2R135 PF11570.8 RUS85634.1 - 2.8 8.2 9.5 25 5.2 0.7 3.8 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF4407 PF14362.6 RUS85634.1 - 3.8 6.8 31.8 0.26 10.6 16.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 RUS85634.1 - 4.1 7.4 51.1 2.6 8.0 29.6 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 RUS85634.1 - 4.2 6.2 46.8 1 8.1 26.2 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 RUS85634.1 - 5.7 6.1 32.1 2.5 7.3 8.4 2.6 1 1 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 RUS85634.1 - 6.3 6.8 29.8 0.58 10.2 10.0 3.5 2 1 0 3 3 3 0 Laminin Domain II PIG-L PF02585.17 RUS85635.1 - 2.7e-26 92.8 0.0 3.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.32 RUS85636.1 - 1.1e-15 57.7 10.8 4.6e-05 24.1 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85636.1 - 0.043 14.1 0.0 1.4 9.3 0.0 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CBF PF03914.17 RUS85637.1 - 1.2e-29 103.5 0.9 5.1e-29 101.5 0.4 2.2 2 1 0 2 2 2 1 CBF/Mak21 family RE_LlaJI PF09563.10 RUS85637.1 - 0.075 12.2 0.2 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 LlaJI restriction endonuclease zinc_ribbon_6 PF14599.6 RUS85637.1 - 0.11 12.5 0.9 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Zinc-ribbon EP400_N PF15790.5 RUS85638.1 - 7.5e-26 91.0 11.9 1.4e-25 90.1 11.8 1.4 1 1 0 1 1 1 1 E1A-binding protein p400, N-terminal PKD_channel PF08016.12 RUS85639.1 - 2.2e-144 481.3 16.1 2.2e-144 481.3 16.1 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 RUS85639.1 - 5.1e-25 88.1 32.2 2.1e-24 86.1 28.9 2.2 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 RUS85639.1 - 5.1e-09 36.2 0.2 1e-08 35.3 0.2 1.5 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_1 PF00036.32 RUS85639.1 - 2.1e-06 26.9 3.1 0.047 13.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS85639.1 - 0.00079 19.2 1.6 0.32 11.0 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS85639.1 - 0.055 13.9 8.8 0.72 10.4 0.2 3.4 3 0 0 3 3 3 0 EF-hand domain pair STAT_alpha PF01017.20 RUS85639.1 - 0.06 13.2 1.6 1.4 8.8 1.5 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain EF-hand_5 PF13202.6 RUS85639.1 - 0.31 10.6 2.1 23 4.7 0.1 2.8 2 0 0 2 2 2 0 EF hand PKD_channel PF08016.12 RUS85640.1 - 1e-143 479.1 17.9 1e-143 479.1 17.9 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 RUS85640.1 - 1.9e-28 99.4 42.1 5.2e-26 91.4 37.4 2.3 2 0 0 2 2 2 2 Ion transport protein Fer4_24 PF18109.1 RUS85640.1 - 0.074 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain adh_short PF00106.25 RUS85641.1 - 3.9e-43 147.2 0.0 5.4e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS85641.1 - 6.3e-28 97.9 0.0 9.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 RUS85641.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2298 PF10060.9 RUS85641.1 - 0.032 13.0 0.5 0.041 12.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) CDP-OH_P_tran_2 PF08009.11 RUS85641.1 - 0.87 9.5 9.8 0.32 10.9 6.8 1.9 1 1 1 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 FXMR_C2 PF16098.5 RUS85642.1 - 0.15 12.5 20.5 2.3 8.8 3.7 3.7 1 1 1 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 AIB PF15334.6 RUS85642.1 - 0.26 10.6 5.0 1.3 8.2 1.0 2.3 1 1 1 2 2 2 0 Aurora kinase A and ninein interacting protein DUF4741 PF15897.5 RUS85642.1 - 3.9 7.3 6.3 10 5.9 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4741) PTR2 PF00854.21 RUS85643.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 POT family MgtE_N PF03448.17 RUS85643.1 - 0.1 13.2 2.5 17 6.1 0.0 3.6 3 1 0 3 3 3 0 MgtE intracellular N domain PTR2 PF00854.21 RUS85644.1 - 3.3e-31 108.5 15.0 1.4e-26 93.3 7.2 2.1 1 1 1 2 2 2 2 POT family SURF4 PF02077.15 RUS85644.1 - 0.42 10.2 4.6 1.3 8.6 0.2 2.6 3 0 0 3 3 3 0 SURF4 family Cadherin PF00028.17 RUS85645.1 - 0 1385.6 188.3 1.2e-15 57.7 0.1 48.0 46 2 1 47 47 47 46 Cadherin domain RET_CLD1 PF17756.1 RUS85645.1 - 1.2e-18 67.6 0.0 3 8.2 0.0 15.8 21 1 1 22 22 22 4 RET Cadherin like domain 1 Y_Y_Y PF07495.13 RUS85645.1 - 6.3e-05 22.8 0.0 24 5.0 0.0 8.9 8 0 0 8 8 8 1 Y_Y_Y domain Cadherin_4 PF17803.1 RUS85645.1 - 0.022 15.4 0.1 0.022 15.4 0.1 29.1 32 3 1 33 33 33 0 Bacterial cadherin-like domain DUF4522 PF15022.6 RUS85646.1 - 0.028 14.7 0.2 2.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4522) DUF3930 PF13067.6 RUS85646.1 - 2.8 8.2 8.5 13 6.1 1.8 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3930) HTHP PF11534.8 RUS85646.1 - 4.7 7.7 13.8 48 4.5 1.5 4.5 1 1 4 5 5 5 0 Hexameric tyrosine-coordinated heme protein (HTHP) Cadherin PF00028.17 RUS85647.1 - 6.1e-89 292.6 35.5 1.1e-14 54.6 0.8 9.9 10 0 0 10 10 10 9 Cadherin domain RET_CLD1 PF17756.1 RUS85647.1 - 7.8e-06 26.2 0.0 0.091 13.0 0.0 3.5 4 0 0 4 4 4 2 RET Cadherin like domain 1 Cadherin_pro PF08758.11 RUS85647.1 - 0.00097 19.3 0.0 0.15 12.2 0.0 4.3 4 0 0 4 4 4 1 Cadherin prodomain like VCPO_N PF17897.1 RUS85647.1 - 0.0032 17.3 2.4 0.61 9.8 0.1 2.8 2 0 0 2 2 2 2 Vanadium chloroperoxidase N-terminal domain Y_Y_Y PF07495.13 RUS85647.1 - 1.4 8.9 7.6 26 4.9 0.1 6.2 9 0 0 9 9 9 0 Y_Y_Y domain Cadherin PF00028.17 RUS85648.1 - 1.5e-37 127.9 13.9 1.8e-09 37.9 0.3 6.3 6 0 0 6 6 6 6 Cadherin domain DUF4958 PF16319.5 RUS85648.1 - 0.002 16.2 0.5 0.0027 15.8 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4958) Cadherin_pro PF08758.11 RUS85648.1 - 0.0062 16.7 0.0 3.7 7.8 0.0 3.6 3 0 0 3 3 3 1 Cadherin prodomain like RET_CLD1 PF17756.1 RUS85648.1 - 0.012 15.9 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 RET Cadherin like domain 1 Phage_holin_3_6 PF07332.11 RUS85649.1 - 0.087 12.9 2.1 0.18 11.9 2.1 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Collagen PF01391.18 RUS85650.1 - 1.1e-45 153.2 175.1 8.3e-09 35.1 27.9 7.1 3 2 1 4 4 4 3 Collagen triple helix repeat (20 copies) Macoilin PF09726.9 RUS85650.1 - 1.7 7.1 7.1 2.2 6.8 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Mpp10 PF04006.12 RUS85651.1 - 0.00022 19.9 8.3 0.00022 19.9 8.3 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 RUS85651.1 - 0.52 8.5 27.9 0.68 8.1 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS85651.1 - 4.8 5.2 50.1 6.5 4.7 50.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RTP801_C PF07809.11 RUS85652.1 - 1.5e-31 108.8 0.0 1.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region Ras PF00071.22 RUS85655.1 - 1.1e-56 190.9 0.4 1.5e-56 190.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85655.1 - 1.8e-31 108.9 0.1 3.2e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85655.1 - 8.7e-15 54.6 0.2 1.1e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS85655.1 - 2.8e-07 30.1 0.1 3.2e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS85655.1 - 0.00018 21.6 0.0 0.00059 19.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS85655.1 - 0.0014 18.2 0.2 0.0026 17.3 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS85655.1 - 0.0096 15.8 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 RUS85655.1 - 0.02 14.4 0.0 0.07 12.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 RUS85655.1 - 0.024 14.7 0.3 0.11 12.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain DUF5050 PF16472.5 RUS85655.1 - 0.027 13.7 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) DMA PF03474.14 RUS85656.1 - 2.7e-13 49.2 0.1 2.4 7.8 0.0 7.0 7 0 0 7 7 7 5 DMRTA motif UL11 PF11094.8 RUS85656.1 - 1.8e-05 24.5 12.9 1.9 8.4 0.1 6.8 1 1 4 7 7 7 1 Membrane-associated tegument protein SAM_decarbox PF01536.16 RUS85656.1 - 0.0025 16.9 10.6 2.6 7.0 0.2 5.3 1 1 5 6 6 6 2 Adenosylmethionine decarboxylase UPAR_LY6_2 PF16975.5 RUS85656.1 - 0.0047 17.1 8.1 6.4 7.0 0.2 3.6 1 1 3 5 5 5 4 Ly6/PLAUR domain-containing protein 6, Lypd6 POT1 PF02765.17 RUS85656.1 - 0.0066 16.3 3.6 1.7 8.5 0.2 3.0 1 1 2 3 3 3 3 Telomeric single stranded DNA binding POT1/CDC13 EZH2_WD-Binding PF11616.8 RUS85656.1 - 0.028 14.5 9.8 1.2e+02 2.9 0.1 5.9 5 1 1 6 6 6 0 WD repeat binding protein EZH2 BtpA PF03437.15 RUS85656.1 - 0.081 12.3 1.8 2.7 7.4 0.3 2.6 1 1 1 2 2 2 0 BtpA family DUF3948 PF13134.6 RUS85656.1 - 0.16 11.7 4.1 23 4.8 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3948) UCMA PF17085.5 RUS85656.1 - 0.38 10.8 10.0 13 5.8 0.2 4.1 1 1 5 6 6 6 0 Unique cartilage matrix associated protein IKI3 PF04762.12 RUS85656.1 - 1.6 6.7 7.8 1.9 6.4 7.8 1.0 1 0 0 1 1 1 0 IKI3 family Aldedh PF00171.22 RUS85657.1 - 9.8e-134 446.3 0.1 1.1e-133 446.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RUS85657.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) I-set PF07679.16 RUS85660.1 - 2e-76 252.1 0.0 4e-14 52.4 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS85660.1 - 2.5e-73 242.7 0.6 2.8e-15 56.7 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 RUS85660.1 - 5.4e-49 164.4 0.1 1e-09 38.6 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 RUS85660.1 - 3.2e-43 145.8 2.2 5.2e-08 32.9 0.1 6.9 6 1 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 RUS85660.1 - 1.8e-22 79.5 2.4 0.0075 16.4 0.1 9.6 6 4 0 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS85660.1 - 8.6e-17 61.0 0.5 0.0074 16.3 0.0 6.3 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS85660.1 - 2.1e-10 40.9 0.0 0.27 11.6 0.0 5.4 6 0 0 6 6 5 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS85660.1 - 8e-10 38.8 0.0 0.21 11.9 0.0 4.9 4 0 0 4 4 4 3 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 RUS85660.1 - 9.8e-09 35.5 5.1 0.00017 21.9 0.2 3.7 3 0 0 3 3 3 2 Fibronectin type III domain Ig_6 PF18452.1 RUS85660.1 - 6.2e-08 32.1 0.0 0.0083 15.7 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin domain C1-set PF07654.15 RUS85660.1 - 2.7e-06 27.7 0.0 0.52 10.7 0.0 4.8 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 RUS85660.1 - 4.1e-05 23.6 0.1 16 5.7 0.0 4.5 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS85660.1 - 0.00012 22.1 0.1 0.42 10.7 0.0 4.6 5 1 0 5 5 4 1 C17orf99 Ig domain Gin PF10764.9 RUS85661.1 - 0.00084 19.3 5.2 0.17 11.9 0.0 3.9 2 1 2 4 4 4 1 Inhibitor of sigma-G Gin zf-FLZ PF04570.14 RUS85661.1 - 0.0029 17.0 2.8 6.5 6.3 0.0 4.1 1 1 3 4 4 4 1 zinc-finger of the FCS-type, C2-C2 HGWP PF03578.15 RUS85661.1 - 0.011 15.2 22.6 3.3 7.3 0.2 5.3 5 0 0 5 5 5 0 HGWP repeat Sgf11 PF08209.11 RUS85661.1 - 0.02 14.5 8.8 15 5.2 0.0 4.9 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) DUF2644 PF10841.8 RUS85661.1 - 0.021 15.0 0.4 3.4 8.0 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2644) DUF2039 PF10217.9 RUS85661.1 - 0.066 13.6 8.4 4 7.8 0.3 3.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-UDP PF14569.6 RUS85661.1 - 0.25 11.5 4.1 0.51 10.5 0.1 2.5 1 1 2 3 3 3 0 Zinc-binding RING-finger zf-C4_Topoisom PF01396.19 RUS85661.1 - 2.2 8.1 6.9 1.1e+02 2.7 0.1 4.4 5 0 0 5 5 5 0 Topoisomerase DNA binding C4 zinc finger eIF-5_eIF-2B PF01873.17 RUS85661.1 - 2.7 7.9 9.6 10 6.0 0.5 3.0 1 1 3 4 4 4 0 Domain found in IF2B/IF5 C1_2 PF03107.16 RUS85661.1 - 3 8.2 17.8 11 6.4 1.3 4.9 1 1 2 3 3 3 0 C1 domain Tnp_zf-ribbon_2 PF13842.6 RUS85661.1 - 8 7.4 19.4 41 5.1 0.2 4.8 4 1 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon Cytochrome_C7 PF14522.6 RUS85661.1 - 8.4 6.5 10.3 2.2 8.3 4.2 2.8 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Tubulin PF00091.25 RUS85662.1 - 2.9e-51 174.5 0.0 4.1e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS85662.1 - 3.3e-42 143.6 0.0 5.5e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS85662.1 - 0.0032 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Fasciclin PF02469.22 RUS85664.1 - 1.1e-24 87.1 0.1 2.1e-07 31.2 0.0 3.9 3 1 1 4 4 4 3 Fasciclin domain TBP PF00352.21 RUS85664.1 - 0.0014 18.5 1.8 36 4.4 0.0 4.4 2 2 1 4 4 4 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2418 PF10332.9 RUS85664.1 - 0.86 10.2 29.6 57 4.3 0.7 7.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2418) AAA_11 PF13086.6 RUS85664.1 - 9.9 5.9 19.1 16 5.1 19.1 1.4 1 0 0 1 1 1 0 AAA domain CAP PF00188.26 RUS85665.1 - 1e-21 78.1 3.5 1.3e-21 77.7 3.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 RUS85666.1 - 1.1e-06 28.4 0.1 3.6e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Presenilin PF01080.17 RUS85666.1 - 0.012 14.4 13.7 0.017 13.9 13.7 1.3 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.14 RUS85666.1 - 0.044 13.2 10.7 0.08 12.3 10.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SRP-alpha_N PF04086.13 RUS85666.1 - 0.29 11.0 30.1 0.059 13.3 26.4 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF2201_N PF13203.6 RUS85666.1 - 0.51 9.9 8.8 1 8.9 8.8 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF5308 PF17233.2 RUS85666.1 - 0.79 9.9 5.5 1.8 8.8 5.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Serinc PF03348.15 RUS85666.1 - 0.85 8.5 4.7 1.1 8.2 4.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.12 RUS85666.1 - 1.5 7.7 8.7 2.2 7.2 8.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 RUS85666.1 - 1.6 7.5 29.3 0.46 9.2 26.3 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS85666.1 - 1.8 6.8 27.9 2.9 6.1 27.9 1.3 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 RUS85666.1 - 2.3 7.6 23.4 0.48 9.8 19.4 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) YL1 PF05764.13 RUS85666.1 - 3.1 7.9 46.5 0.12 12.5 40.8 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Pkinase_Tyr PF07714.17 RUS85667.1 - 4.1e-57 193.4 0.0 3.8e-48 164.0 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS85667.1 - 2.2e-34 119.1 0.0 2.1e-27 96.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 RUS85667.1 - 0.0057 16.6 0.1 8.5 6.2 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS85667.1 - 0.025 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Glyco_transf_11 PF01531.16 RUS85667.1 - 0.085 12.1 0.1 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 11 FeoB_Cyto PF17910.1 RUS85667.1 - 0.16 12.5 0.9 0.77 10.3 0.1 2.5 2 0 0 2 2 2 0 FeoB cytosolic helical domain DUF4027 PF13219.6 RUS85668.1 - 6e-06 26.0 5.3 36 4.3 0.0 8.1 9 0 0 9 9 9 0 Protein of unknown function (DUF4027) DUF4854 PF16146.5 RUS85668.1 - 1.9e-05 24.9 2.7 90 3.5 0.0 6.4 1 1 7 8 8 8 0 Domain of unknown function (DUF4854) P_proprotein PF01483.20 RUS85668.1 - 0.00059 19.8 10.8 23 5.1 0.3 6.6 1 1 6 7 7 7 0 Proprotein convertase P-domain Phage_integr_3 PF16795.5 RUS85668.1 - 0.0022 18.0 2.0 9.8 6.1 0.1 3.1 1 1 3 4 4 4 3 Archaeal phage integrase PGM_PMM_IV PF00408.20 RUS85668.1 - 0.0032 17.6 23.0 9.9 6.4 1.0 6.5 1 1 5 6 6 6 3 Phosphoglucomutase/phosphomannomutase, C-terminal domain ArAE_2_N PF10337.9 RUS85668.1 - 0.0058 15.7 1.4 12 4.9 0.0 3.4 1 1 2 4 4 4 2 Putative ER transporter, 6TM, N-terminal TctC PF03401.14 RUS85668.1 - 0.019 14.1 2.8 28 3.6 0.1 3.6 1 1 3 4 4 4 0 Tripartite tricarboxylate transporter family receptor Glyco_hydro38C2 PF17677.1 RUS85668.1 - 0.073 13.2 0.1 84 3.4 0.0 3.3 1 1 3 4 4 4 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PBP3 PF18056.1 RUS85668.1 - 0.2 11.8 5.8 14 5.9 0.3 2.9 1 1 2 3 3 3 0 Penicillin Binding Protein 3 Domain Bap31 PF05529.12 RUS85669.1 - 2.6e-45 153.6 2.5 4.8e-45 152.7 2.5 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 RUS85669.1 - 6.1e-11 42.1 11.0 6.1e-11 42.1 11.0 1.9 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain FHIPEP PF00771.20 RUS85669.1 - 0.75 8.2 4.2 0.14 10.6 0.8 1.5 2 0 0 2 2 2 0 FHIPEP family Zip PF02535.22 RUS85669.1 - 1.3 8.2 4.3 3.3 6.8 4.3 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter APG6_N PF17675.1 RUS85669.1 - 1.4 9.4 18.6 2.9 8.4 18.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 RUS85669.1 - 2.2 8.3 14.4 12 6.0 14.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rx_N PF18052.1 RUS85669.1 - 2.8 8.3 7.3 1.2 9.5 0.5 2.4 1 1 1 2 2 2 0 Rx N-terminal domain DivIC PF04977.15 RUS85669.1 - 8 6.3 10.1 11 5.8 3.5 3.1 2 1 1 3 3 3 0 Septum formation initiator CBM_14 PF01607.24 RUS85670.1 - 9.3e-08 32.1 1.5 1.4e-07 31.5 0.7 1.7 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Nucleoporin2 PF04096.14 RUS85670.1 - 0.069 13.3 0.0 12 6.0 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin autopeptidase CarbpepA_inh PF02977.15 RUS85672.1 - 0.031 14.1 2.0 0.12 12.2 2.0 2.0 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor POTRA_2 PF08479.11 RUS85674.1 - 2.5 8.0 6.5 65 3.5 0.1 3.8 1 1 6 7 7 7 0 POTRA domain, ShlB-type Collagen PF01391.18 RUS85674.1 - 3.1 7.6 10.6 1.3e+02 2.4 10.6 2.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) CHB_HEX_C_1 PF13290.6 RUS85675.1 - 2.2e-13 50.0 0.0 4.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 RUS85675.1 - 5.3e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Fn3 associated Ank_4 PF13637.6 RUS85675.1 - 2.4e-10 40.7 0.0 1.8e-05 25.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS85675.1 - 1.2e-09 38.6 0.1 5e-09 36.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS85675.1 - 2e-09 37.5 0.5 0.0025 18.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 RUS85675.1 - 9.2e-09 34.9 0.1 0.027 15.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 RUS85675.1 - 1.4e-07 31.7 0.4 0.00015 22.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ATP-synt_DE PF00401.20 RUS85675.1 - 0.014 15.7 0.7 0.029 14.6 0.7 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain EMP24_GP25L PF01105.24 RUS85676.1 - 2.9e-49 167.5 0.2 3.5e-49 167.2 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3471 PF11954.8 RUS85676.1 - 0.091 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) DUF4590 PF15257.6 RUS85677.1 - 0.0073 16.2 0.5 0.065 13.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4590) Tctex-1 PF03645.13 RUS85678.1 - 1.3e-22 79.9 0.0 3.2e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Tctex-1 family RE_Bpu10I PF09549.10 RUS85678.1 - 0.039 13.5 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Bpu10I restriction endonuclease GOLD_2 PF13897.6 RUS85679.1 - 4.9e-71 237.6 3.1 4.9e-71 237.6 3.1 2.7 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 RUS85679.1 - 1.7e-12 47.4 0.0 1.7e-12 47.4 0.0 3.1 3 1 0 3 3 3 1 Acyl CoA binding protein SOBP PF15279.6 RUS85679.1 - 0.3 11.7 10.7 0.55 10.8 10.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.13 RUS85679.1 - 2.4 8.1 35.9 6.7 6.6 36.1 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_3 PF12698.7 RUS85679.1 - 4.9 6.2 9.5 7 5.7 9.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DDE_Tnp_IS1595 PF12762.7 RUS85680.1 - 3e-16 59.8 0.0 7e-16 58.6 0.0 1.5 2 0 0 2 2 2 1 ISXO2-like transposase domain DUF1137 PF06587.11 RUS85680.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) ABC2_membrane PF01061.24 RUS85681.1 - 6.6e-33 113.9 22.6 1.3e-32 113.0 22.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RUS85681.1 - 1.4e-25 90.4 0.1 2.5e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS85681.1 - 3e-08 33.8 2.6 3.4e-06 27.1 0.3 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS85681.1 - 0.0034 17.1 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 RUS85681.1 - 0.004 16.6 0.3 3.1 7.2 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RUS85681.1 - 0.023 14.6 0.1 0.056 13.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 RUS85681.1 - 0.027 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS85681.1 - 0.053 13.9 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 RUS85681.1 - 0.21 12.1 0.1 0.45 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SirB PF04247.12 RUS85681.1 - 0.33 11.0 7.2 1.1 9.4 2.5 2.4 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Tnp_P_element_C PF12596.8 RUS85684.1 - 0.054 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 87kDa Transposase BAF PF02961.14 RUS85685.1 - 2.4e-41 140.0 0.5 5.3e-41 139.0 0.5 1.6 1 0 0 1 1 1 1 Barrier to autointegration factor THAP PF05485.12 RUS85685.1 - 1.2e-14 55.0 6.3 4.6e-13 49.9 2.7 2.7 2 0 0 2 2 2 2 THAP domain Sugarporin_N PF11471.8 RUS85685.1 - 0.052 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension GrpE PF01025.19 RUS85685.1 - 6.3 6.4 6.9 11 5.6 6.9 1.6 1 1 0 1 1 1 0 GrpE fn3 PF00041.21 RUS85687.1 - 0.00017 21.9 0.1 0.012 15.9 0.0 3.2 3 0 0 3 3 3 1 Fibronectin type III domain Pkinase_Tyr PF07714.17 RUS85688.1 - 3.1e-69 233.1 0.0 3.5e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS85688.1 - 3.1e-29 102.1 0.0 5.3e-29 101.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 RUS85688.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RUS85688.1 - 0.057 13.3 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS85688.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF779 PF05610.11 RUS85688.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF779) TGF_beta PF00019.20 RUS85690.1 - 4.3e-33 114.4 1.0 1.8e-32 112.4 1.0 2.1 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS85690.1 - 3e-30 105.8 0.0 5.8e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 TGF-beta propeptide Macoilin PF09726.9 RUS85690.1 - 3.9 5.9 14.8 0.14 10.7 1.3 2.2 2 0 0 2 2 2 0 Macoilin family WD40 PF00400.32 RUS85693.1 - 6.6e-23 80.6 9.9 4.7e-08 33.6 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85693.1 - 0.0019 18.5 0.0 2.5 8.4 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 RUS85693.1 - 0.058 13.8 0.5 5.8 7.4 0.0 2.9 1 1 2 3 3 3 0 STE like transcription factor F-box-like PF12937.7 RUS85694.1 - 8.4e-13 48.0 1.4 1.6e-12 47.1 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS85694.1 - 1.3e-11 44.1 1.5 2.5e-11 43.2 1.5 1.5 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.6 RUS85694.1 - 0.031 14.5 1.6 0.72 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) DUF2730 PF10805.8 RUS85695.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Phage_HK97_TLTM PF06120.11 RUS85695.1 - 0.033 13.4 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Tail length tape measure protein Paralemmin PF03285.15 RUS85695.1 - 0.034 13.7 1.1 0.091 12.3 1.1 1.7 1 1 0 1 1 1 0 Paralemmin INT_SG_DDX_CT_C PF15300.6 RUS85695.1 - 0.036 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus BNIP3 PF06553.12 RUS85695.1 - 0.11 12.1 1.9 0.35 10.5 0.2 2.0 1 1 1 2 2 2 0 BNIP3 zf-CCHC PF00098.23 RUS85696.1 - 6.1e-06 26.1 3.4 1e-05 25.4 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS85696.1 - 0.0003 20.5 3.3 0.00055 19.7 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS85696.1 - 0.004 17.1 0.2 0.01 15.8 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS85696.1 - 0.026 14.2 1.7 0.05 13.3 1.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.14 RUS85697.1 - 1.5e-35 123.0 0.0 2.3e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS85697.1 - 2.3e-23 82.1 0.4 1.1e-21 76.7 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain Retrotran_gag_2 PF14223.6 RUS85697.1 - 2.7e-17 62.7 0.1 4.5e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-H2C2 PF09337.10 RUS85697.1 - 2.6e-06 27.5 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF4885 PF16226.5 RUS85697.1 - 0.062 12.4 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) DUF3450 PF11932.8 RUS85698.1 - 0.012 14.9 3.6 0.012 14.9 3.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Phlebovirus_NSM PF07246.11 RUS85698.1 - 0.095 12.1 8.0 0.14 11.5 6.8 1.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Occludin_ELL PF07303.13 RUS85698.1 - 2.6 8.8 12.6 7.9 7.3 2.5 3.9 3 1 2 5 5 5 0 Occludin homology domain DUF1515 PF07439.11 RUS85698.1 - 3.9 7.5 7.3 12 5.9 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.19 RUS85698.1 - 5.9 4.7 7.4 9.7 4.0 7.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 RUS85698.1 - 6.1 7.2 10.7 5.3 7.4 8.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) KASH PF10541.9 RUS85699.1 - 0.0005 20.3 0.3 0.0012 19.1 0.1 1.8 2 0 0 2 2 2 1 Nuclear envelope localisation domain BLOC1_2 PF10046.9 RUS85699.1 - 0.034 14.5 4.3 0.082 13.2 0.2 2.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 RUS85699.1 - 0.1 12.7 9.0 0.42 10.7 2.5 3.8 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DASH_Dam1 PF08653.10 RUS85699.1 - 0.2 11.5 2.8 0.66 9.8 0.3 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Sec2p PF06428.11 RUS85699.1 - 0.23 11.4 4.3 0.43 10.6 0.2 2.8 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Spectrin PF00435.21 RUS85699.1 - 1.1 9.8 11.0 2.2 8.8 1.8 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF5082 PF16888.5 RUS85699.1 - 2.6 8.3 6.8 7 6.9 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) AAA_23 PF13476.6 RUS85699.1 - 2.8 8.4 5.3 13 6.2 0.6 2.1 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 RUS85699.1 - 5.1 6.9 8.5 11 5.8 0.0 3.3 4 0 0 4 4 4 0 Septum formation initiator Med29 PF11568.8 RUS85700.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 RT_RNaseH_2 PF17919.1 RUS85701.1 - 1.1e-28 99.2 0.0 2.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS85701.1 - 4e-26 91.3 0.0 8.7e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RUS85701.1 - 1.2e-16 60.5 0.8 5e-16 58.5 0.8 2.2 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS85701.1 - 1.3e-16 60.8 0.0 4.5e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 RUS85701.1 - 4.2e-14 52.6 0.0 9.1e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 RUS85701.1 - 0.0021 17.8 0.0 0.018 14.8 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.10 RUS85701.1 - 0.0063 16.7 0.5 0.02 15.1 0.5 2.0 1 0 0 1 1 1 1 H2C2 zinc finger EPTP PF03736.17 RUS85701.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 EPTP domain Polysacc_deac_2 PF04748.13 RUS85701.1 - 0.093 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase zf-CCHC PF00098.23 RUS85701.1 - 5.1 7.3 10.4 0.079 13.1 1.2 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-U1 PF06220.12 RUS85703.1 - 0.0038 17.0 0.8 0.0038 17.0 0.8 2.0 2 0 0 2 2 2 1 U1 zinc finger Rpr2 PF04032.16 RUS85703.1 - 0.058 13.7 0.6 0.11 12.7 0.2 1.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Hus1 PF04005.12 RUS85704.1 - 1e-87 294.0 0.2 1.1e-87 293.8 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein TMEM18 PF14770.6 RUS85704.1 - 0.03 14.3 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 18 Cadherin_C_2 PF16492.5 RUS85705.1 - 0.71 10.7 5.7 0.24 12.2 2.5 1.9 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Cyclin PF08613.11 RUS85706.1 - 0.099 13.0 0.3 0.12 12.7 0.3 1.1 1 0 0 1 1 1 0 Cyclin DUF4653 PF15546.6 RUS85706.1 - 0.34 10.5 2.6 0.42 10.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) SR-25 PF10500.9 RUS85706.1 - 1 8.9 7.2 1.3 8.6 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cadherin PF00028.17 RUS85707.1 - 4.8e-29 100.6 10.9 8.3e-07 29.4 0.0 7.4 6 1 1 7 7 7 5 Cadherin domain Y_Y_Y PF07495.13 RUS85707.1 - 0.014 15.3 0.2 1.1 9.2 0.0 3.8 4 0 0 4 4 4 0 Y_Y_Y domain FctA PF12892.7 RUS85707.1 - 0.33 11.8 19.7 8.3 7.3 4.0 4.9 2 1 2 4 4 4 0 Spy0128-like isopeptide containing domain SicP-binding PF09119.10 RUS85708.1 - 0.00068 19.6 28.6 3.5 7.7 0.9 6.2 1 1 6 7 7 7 5 SicP binding CUB_2 PF02408.20 RUS85708.1 - 0.00091 19.0 2.8 0.2 11.4 0.1 2.2 1 1 1 2 2 2 2 CUB-like domain DUF2442 PF10387.9 RUS85708.1 - 0.0032 17.7 0.5 27 5.2 0.1 4.0 1 1 5 6 6 6 0 Protein of unknown function (DUF2442) DUF3108 PF11306.8 RUS85708.1 - 0.0036 17.3 5.2 0.71 9.8 0.6 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3108) TOBE PF03459.17 RUS85708.1 - 0.0076 16.5 8.3 7.6 6.9 0.6 4.6 1 1 3 4 4 4 2 TOBE domain FixG_C PF11614.8 RUS85708.1 - 0.017 15.3 12.5 3.9 7.7 12.5 2.4 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase VWD PF00094.25 RUS85708.1 - 0.064 13.5 17.4 1.1 9.5 4.6 2.7 1 1 2 3 3 3 0 von Willebrand factor type D domain TamB PF04357.13 RUS85708.1 - 0.09 12.0 9.3 1.3 8.2 2.7 2.1 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex UBX PF00789.20 RUS85708.1 - 0.092 13.0 14.0 25 5.2 0.3 4.6 2 2 2 4 4 4 0 UBX domain DBB PF14545.6 RUS85708.1 - 0.22 11.4 11.6 2.9 7.8 2.2 3.2 1 1 1 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, AfaD PF05775.12 RUS85708.1 - 0.63 10.5 14.5 12 6.3 0.3 4.9 1 1 3 4 4 4 0 Enterobacteria AfaD invasin protein DUF3389 PF11869.8 RUS85708.1 - 2 8.7 16.1 33 4.7 0.1 5.5 2 2 3 5 5 5 0 Protein of unknown function (DUF3389) Flu_B_M2 PF04772.12 RUS85708.1 - 3.6 7.9 16.4 11 6.3 4.2 3.3 1 1 2 3 3 3 0 Influenza B matrix protein 2 (BM2) DUF2917 PF11142.8 RUS85708.1 - 3.7 7.0 10.1 87 2.6 0.1 4.6 2 2 5 7 7 7 0 Protein of unknown function (DUF2917) PEX-1N PF09262.11 RUS85708.1 - 5 7.6 19.0 1.8e+04 -8.5 19.0 4.1 1 1 0 1 1 0 0 Peroxisome biogenesis factor 1, N-terminal DUF2500 PF10694.9 RUS85708.1 - 6.9 7.2 16.3 7.2 7.2 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) CBM_4_9 PF02018.17 RUS85708.1 - 9.2 6.5 7.3 27 5.0 2.3 2.5 1 1 1 2 2 2 0 Carbohydrate binding domain FAS_meander PF17951.1 RUS85708.1 - 9.3 6.1 13.6 9.9 6.0 2.6 2.3 1 1 1 2 2 2 0 Fatty acid synthase meander beta sheet domain 7tm_1 PF00001.21 RUS85709.1 - 1.6e-06 27.6 21.5 3.9e-06 26.4 21.5 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS85709.1 - 1.8e-05 24.5 26.9 3.1e-05 23.8 26.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srh PF10318.9 RUS85709.1 - 0.00013 21.1 7.6 0.00013 21.1 7.6 2.9 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srh 7TM_GPCR_Srsx PF10320.9 RUS85709.1 - 0.0072 15.7 27.6 0.0079 15.6 26.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3169 PF11368.8 RUS85709.1 - 0.014 15.0 1.5 0.014 15.0 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) CstA_5TM PF13722.6 RUS85709.1 - 0.08 13.3 0.4 0.08 13.3 0.4 2.5 2 1 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA 7tm_1 PF00001.21 RUS85710.1 - 5.2e-07 29.2 19.1 6.7e-07 28.9 18.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS85710.1 - 0.00039 20.1 17.7 0.00039 20.1 17.7 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Myosin_tail_1 PF01576.19 RUS85712.1 - 4e-14 51.5 98.3 7.1e-12 44.0 76.8 2.0 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.21 RUS85713.1 - 8.1e-19 67.3 0.3 2.3e-18 65.8 0.0 1.9 2 1 1 3 3 3 1 Myosin head (motor domain) DivIC PF04977.15 RUS85713.1 - 9.6e-06 25.3 15.5 0.0001 22.0 2.6 2.8 1 1 0 2 2 2 2 Septum formation initiator DHC_N1 PF08385.12 RUS85713.1 - 3.3e-05 22.7 5.4 4.4e-05 22.3 5.4 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 IQ PF00612.27 RUS85713.1 - 0.0007 19.2 3.4 0.015 15.0 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF4200 PF13863.6 RUS85713.1 - 0.0019 18.6 20.9 0.0019 18.6 20.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) MCC-bdg_PDZ PF10506.9 RUS85713.1 - 0.0072 16.3 1.3 0.0072 16.3 1.3 2.6 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome ADIP PF11559.8 RUS85713.1 - 0.0073 16.4 9.0 0.0073 16.4 9.0 2.5 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 RUS85713.1 - 0.028 13.9 15.7 0.051 13.0 15.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 RUS85713.1 - 0.091 13.0 24.9 0.49 10.6 25.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Lipoprotein_6 PF01441.19 RUS85713.1 - 0.41 10.6 5.2 0.72 9.8 5.2 1.3 1 0 0 1 1 1 0 Lipoprotein DUF812 PF05667.11 RUS85713.1 - 0.42 9.4 18.3 0.74 8.6 18.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.8 RUS85713.1 - 0.6 10.1 24.8 0.19 11.7 13.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Tho2 PF11262.8 RUS85713.1 - 0.89 8.7 7.5 0.57 9.3 5.8 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 RUS85713.1 - 0.98 8.9 8.3 1.4 8.5 8.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2968 PF11180.8 RUS85713.1 - 1 9.0 18.1 0.26 10.9 15.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4407 PF14362.6 RUS85713.1 - 1.3 8.3 9.2 2 7.7 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myosin_head PF00063.21 RUS85714.1 - 1.7e-91 307.5 0.0 3.3e-90 303.2 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 RUS85714.1 - 0.0015 18.9 0.9 0.0057 17.1 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS85714.1 - 0.012 15.9 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RUS85714.1 - 0.036 14.0 0.1 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 RUS85714.1 - 0.06 13.9 0.2 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 RUS85714.1 - 0.076 12.9 0.2 0.78 9.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 RUS85714.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 RUS85714.1 - 0.22 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit PDZ PF00595.24 RUS85715.1 - 1.8e-11 44.2 0.1 3.5e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS85715.1 - 4e-08 33.0 0.0 8.2e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS85715.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain CI-B14_5a PF07347.12 RUS85715.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.2 4 0 0 4 4 4 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) LRV PF01816.17 RUS85715.1 - 0.62 10.6 2.6 11 6.6 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat variant Metallophos PF00149.28 RUS85716.1 - 2.4e-41 142.5 0.1 3.2e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS85716.1 - 0.00086 19.7 2.9 0.0013 19.1 0.5 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 RUS85716.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DERM PF14704.6 RUS85717.1 - 4e-45 154.0 0.6 4.7e-45 153.8 0.6 1.0 1 0 0 1 1 1 1 Dermatopontin Transposase_1 PF01359.18 RUS85718.1 - 5.8e-15 54.9 0.0 9.5e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS85718.1 - 0.0005 19.8 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TNF PF00229.18 RUS85719.1 - 0.00016 21.7 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family PFK PF00365.20 RUS85721.1 - 5e-175 580.6 4.5 3.9e-102 341.4 2.5 2.2 2 0 0 2 2 2 2 Phosphofructokinase Endonuc-PvuII PF09225.10 RUS85722.1 - 0.0036 17.1 1.3 1.8 8.3 0.1 2.3 2 0 0 2 2 2 2 Restriction endonuclease PvuII Pet100 PF09803.9 RUS85722.1 - 1.6 9.3 13.4 33 5.1 0.3 4.2 1 1 3 4 4 4 0 Pet100 DUF2066 PF09839.9 RUS85722.1 - 2.1 7.7 9.1 5.3 6.4 0.6 3.3 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2066) Sld7_N PF18636.1 RUS85722.1 - 5.1 7.4 8.0 19 5.6 0.8 2.5 1 1 1 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain Tctex-1 PF03645.13 RUS85723.1 - 8.2e-21 74.2 0.1 1.1e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF1647 PF07801.11 RUS85724.1 - 2.1e-08 34.0 0.0 4.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Drc1-Sld2 PF11719.8 RUS85724.1 - 0.0017 17.9 16.6 0.0037 16.9 16.6 1.4 1 1 0 1 1 1 1 DNA replication and checkpoint protein Nop14 PF04147.12 RUS85724.1 - 0.036 12.3 37.1 0.051 11.8 37.1 1.2 1 0 0 1 1 1 0 Nop14-like family GET2 PF08690.10 RUS85724.1 - 0.042 13.5 6.2 0.087 12.5 6.2 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Sugar-bind PF04198.13 RUS85724.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain SID-1_RNA_chan PF13965.6 RUS85724.1 - 0.25 9.7 0.4 0.36 9.2 0.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dynactin_p62 PF05502.13 RUS85724.1 - 0.25 10.1 8.9 0.42 9.3 8.9 1.3 1 0 0 1 1 1 0 Dynactin p62 family PDDEXK_6 PF04720.12 RUS85724.1 - 0.87 9.5 11.5 1.9 8.4 11.5 1.7 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Mpp10 PF04006.12 RUS85724.1 - 1.1 7.6 37.1 1.8 6.9 37.1 1.3 1 0 0 1 1 1 0 Mpp10 protein Connexin PF00029.19 RUS85724.1 - 4 7.1 12.7 27 4.4 13.1 2.0 2 0 0 2 2 2 0 Connexin RRN3 PF05327.11 RUS85724.1 - 4.1 5.8 22.1 6.1 5.3 22.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MIF4G_like_2 PF09090.11 RUS85724.1 - 9.3 5.6 14.4 16 4.8 14.4 1.3 1 0 0 1 1 1 0 MIF4G like Na_sulph_symp PF00939.19 RUS85725.1 - 2.7e-09 36.6 4.7 3.1e-09 36.4 4.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region zinc_ribbon_4 PF13717.6 RUS85725.1 - 0.054 13.4 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain SSF PF00474.17 RUS85727.1 - 9.9e-45 153.1 4.9 1.4e-44 152.6 4.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 RUS85728.1 - 0.00024 20.1 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Chromate_transp PF02417.15 RUS85728.1 - 0.0032 17.6 0.5 0.0057 16.8 0.5 1.3 1 0 0 1 1 1 1 Chromate transporter DUF5518 PF17647.1 RUS85728.1 - 0.035 14.3 0.8 0.04 14.1 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5518) DUF4094 PF13334.6 RUS85728.1 - 0.21 12.1 1.0 0.48 10.9 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4094) Ferritin-like PF12902.7 RUS85729.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Ferritin-like GST_N PF02798.20 RUS85730.1 - 7.1e-11 42.3 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RUS85730.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS85730.1 - 2.8e-09 37.1 0.0 7.1e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS85730.1 - 4.1e-07 30.2 0.0 8.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS85730.1 - 4.7e-06 26.5 0.0 7.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS85730.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS85730.1 - 0.005 17.5 0.0 0.042 14.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 RUS85731.1 - 4.7e-12 46.1 0.2 1.3e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RUS85731.1 - 3.7e-09 36.9 0.0 9e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS85731.1 - 3.5e-05 24.0 0.0 8.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS85731.1 - 0.00014 22.1 0.0 0.00047 20.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS85731.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS85731.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol_delta_4 PF04081.13 RUS85732.1 - 1.6e-16 60.9 0.0 1.9e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Ribosomal_L23eN PF03939.13 RUS85733.1 - 3.7e-23 81.5 11.4 3.7e-23 81.5 11.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 RUS85733.1 - 1.8e-16 60.3 2.7 1.8e-16 60.3 2.7 2.5 2 2 0 2 2 2 1 Ribosomal protein L23 Hydrophobin PF01185.18 RUS85733.1 - 0.056 14.1 0.1 0.1 13.3 0.1 1.4 1 0 0 1 1 1 0 Fungal hydrophobin Abhydrolase_1 PF00561.20 RUS85735.1 - 5e-21 75.5 0.0 6.2e-20 71.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS85735.1 - 3.6e-16 60.4 0.0 4.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS85735.1 - 1.3e-13 50.8 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 RUS85735.1 - 0.00016 20.5 0.0 0.0005 18.9 0.0 1.7 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 RUS85735.1 - 0.0017 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 RUS85735.1 - 0.003 17.3 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein PAF-AH_p_II PF03403.13 RUS85735.1 - 0.0049 15.4 0.2 0.31 9.5 0.0 2.8 2 1 1 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 RUS85735.1 - 0.0086 15.0 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 RUS85735.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 RUS85735.1 - 0.018 14.8 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 RUS85735.1 - 0.038 13.0 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase rve PF00665.26 RUS85737.1 - 1e-28 99.9 0.0 1.9e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain rve_3 PF13683.6 RUS85737.1 - 2.3e-10 40.1 0.0 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 RUS85737.1 - 3.2e-06 26.8 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS85737.1 - 0.031 14.8 0.0 0.087 13.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Metallophos PF00149.28 RUS85738.1 - 4e-16 60.1 0.6 6.6e-16 59.4 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ARTD15_N PF18084.1 RUS85738.1 - 3.2e-07 30.5 0.8 1.3e-06 28.6 0.1 2.4 2 1 0 2 2 2 1 ARTD15 N-terminal domain UBA PF00627.31 RUS85738.1 - 3.7e-06 26.7 0.0 6.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain RGS PF00615.19 RUS85739.1 - 0.024 14.9 0.4 0.33 11.2 0.1 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain DisA-linker PF10635.9 RUS85739.1 - 0.034 13.9 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region PHR PF08005.12 RUS85740.1 - 1.1e-51 175.4 1.1 2.4e-51 174.4 1.1 1.6 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 RUS85740.1 - 4.8e-27 94.4 0.0 2.4e-25 88.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS85740.1 - 3.6e-09 36.6 0.7 4.5e-08 33.1 0.4 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch AAR2 PF05282.11 RUS85741.1 - 9.1e-107 357.5 0.4 1e-106 357.3 0.4 1.0 1 0 0 1 1 1 1 AAR2 protein B9-C2 PF07162.11 RUS85742.1 - 6.1e-51 173.0 0.0 7.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein YdjC PF04794.12 RUS85743.1 - 5.9e-57 193.3 0.0 6.7e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein ECH_1 PF00378.20 RUS85744.1 - 1.1e-92 309.9 0.6 1.2e-92 309.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RUS85744.1 - 5.7e-39 134.5 1.8 1.6e-34 119.9 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 RUS85744.1 - 0.0085 16.1 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 1 Peptidase family S49 zf-C4_ClpX PF06689.13 RUS85744.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger An_peroxidase PF03098.15 RUS85745.1 - 1.1e-163 545.6 0.0 1.3e-163 545.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Tet_JBP PF12851.7 RUS85746.1 - 9.2e-90 301.4 0.7 1.2e-72 245.1 0.3 2.3 2 0 0 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily RNA_polI_A34 PF08208.11 RUS85747.1 - 0.87 9.6 29.6 0.057 13.5 8.5 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase_Tyr PF07714.17 RUS85750.1 - 5.4e-100 333.9 0.0 6.8e-100 333.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS85750.1 - 4.2e-48 164.0 0.0 8.5e-48 163.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RUS85750.1 - 0.064 12.6 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like HCV_NS5a_C PF12941.7 RUS85750.1 - 0.068 13.0 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region adh_short PF00106.25 RUS85751.1 - 4.5e-31 107.8 0.1 1.3e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS85751.1 - 2e-21 76.7 0.0 1.1e-20 74.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS85751.1 - 0.00071 19.5 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Solute_trans_a PF03619.16 RUS85752.1 - 8.2e-31 107.5 4.3 9.4e-31 107.3 4.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Trypsin_2 PF13365.6 RUS85753.1 - 8.2e-05 23.5 0.1 0.00025 22.0 0.0 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Nop14 PF04147.12 RUS85753.1 - 0.0017 16.7 23.2 0.0022 16.3 23.2 1.1 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 RUS85753.1 - 0.0017 16.6 38.0 0.0024 16.1 38.0 1.2 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 RUS85753.1 - 0.012 14.0 17.1 0.016 13.6 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 RUS85753.1 - 0.67 8.7 3.8 0.99 8.1 3.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 RUS85753.1 - 0.88 8.9 29.2 1.3 8.4 29.2 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 RUS85753.1 - 5.2 5.4 25.1 8 4.8 25.1 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF1754 PF08555.10 RUS85753.1 - 5.3 7.9 11.8 84 4.1 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CobT PF06213.12 RUS85753.1 - 8.4 5.7 24.0 15 4.9 24.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 RUS85753.1 - 9.4 5.5 25.1 13 5.0 25.1 1.2 1 0 0 1 1 1 0 BUD22 Sigma54_AID PF00309.20 RUS85756.1 - 2.5e-09 36.9 24.8 19 5.2 0.0 11.6 9 2 3 12 12 12 6 Sigma-54 factor, Activator interacting domain (AID) Prok-TraM PF09228.10 RUS85756.1 - 0.00053 20.3 3.2 4.7 7.6 0.1 3.5 1 1 1 3 3 3 3 Prokaryotic Transcriptional repressor TraM DUF3721 PF12518.8 RUS85756.1 - 4.4 7.2 7.0 1.3e+02 2.5 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function AAA PF00004.29 RUS85757.1 - 0.022 15.2 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS85757.1 - 0.022 15.1 0.0 0.073 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 RUS85757.1 - 0.028 14.0 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 RUS85758.1 - 1.3 8.9 7.0 1.5 8.7 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipoxygenase PF00305.19 RUS85759.1 - 1.6e-33 116.1 0.6 2.2e-28 99.1 0.5 3.4 3 1 1 4 4 4 2 Lipoxygenase PLAT PF01477.23 RUS85759.1 - 2.5e-16 60.3 0.1 6.7e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 PLAT/LH2 domain Cation_ATPase_C PF00689.21 RUS85759.1 - 0.12 12.1 1.0 0.2 11.4 1.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DPPIV_rep PF18811.1 RUS85759.1 - 0.33 10.9 2.2 1 9.4 2.2 1.9 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Colipase-like PF15083.6 RUS85760.1 - 7.5e-10 38.8 35.1 0.00019 21.5 13.8 2.8 1 1 0 2 2 2 2 Colipase-like Pet191_N PF10203.9 RUS85760.1 - 2.7e-08 34.0 41.5 0.35 11.2 3.9 5.7 1 1 6 7 7 7 7 Cytochrome c oxidase assembly protein PET191 SGTA_dimer PF16546.5 RUS85760.1 - 3.5e-07 29.9 36.7 2.8 7.8 0.3 8.2 1 1 6 7 7 7 7 Homodimerisation domain of SGTA Mucin-like PF16058.5 RUS85760.1 - 3.9e-06 26.9 0.1 0.062 13.4 0.0 2.1 1 1 1 2 2 2 2 Mucin-like CHCH PF06747.13 RUS85760.1 - 8.8e-06 25.7 36.8 10 6.4 1.4 8.5 1 1 9 10 10 10 10 CHCH domain SLR1-BP PF07333.12 RUS85760.1 - 0.00018 21.9 32.9 8.9 6.8 1.1 6.1 1 1 2 4 4 4 3 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Phage_fiber PF03335.13 RUS85760.1 - 0.013 15.6 47.9 2.3e+02 2.4 0.1 15.2 16 0 0 16 16 16 0 Phage tail fibre repeat zf-RING_UBOX PF13445.6 RUS85760.1 - 0.26 11.3 31.1 1.8e+04 -22.2 31.1 9.4 1 1 0 1 1 1 0 RING-type zinc-finger Ric8 PF10165.9 RUS85760.1 - 1.1 8.2 10.8 1.8e+02 0.9 10.8 2.2 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Apolipoprotein PF01442.18 RUS85761.1 - 4.6e-20 72.3 30.6 1.1e-08 35.1 12.4 3.3 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF1388 PF07142.12 RUS85762.1 - 3.7e-26 90.7 21.5 6.4e-07 29.2 1.3 6.0 3 2 3 6 6 6 6 Repeat of unknown function (DUF1388) Big_10 PF17964.1 RUS85762.1 - 0.0031 17.5 1.3 23 4.9 0.0 4.4 1 1 5 6 6 6 2 Bacterial Ig domain DUF963 PF06131.11 RUS85762.1 - 0.02 14.3 0.5 45 3.6 0.0 3.8 4 0 0 4 4 4 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF3106 PF11304.8 RUS85762.1 - 0.15 12.5 0.1 5.4 7.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF4367 PF14285.6 RUS85763.1 - 0.56 10.7 8.0 73 3.9 2.5 4.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) DUF3658 PF12395.8 RUS85764.1 - 0.35 10.8 1.8 62 3.6 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function FumaraseC_C PF10415.9 RUS85764.1 - 0.42 11.1 14.7 4.9e+02 1.2 0.0 8.9 11 0 0 11 11 11 0 Fumarase C C-terminus HC2 PF07382.11 RUS85765.1 - 6.2e-05 23.2 0.8 0.0054 16.8 0.8 3.1 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 LIP1 PF15904.5 RUS85765.1 - 0.076 13.4 5.8 1.4e+02 2.9 0.1 6.6 3 2 5 10 10 9 0 LKB1 serine/threonine kinase interacting protein 1 DUF4962 PF16332.5 RUS85765.1 - 3.9 5.9 9.3 17 3.8 0.1 4.1 1 1 3 5 5 5 0 Domain of unknown function (DUF4962) T4-Gluco-transf PF09198.10 RUS85766.1 - 1e-05 25.0 7.9 41 3.9 0.0 9.5 8 4 3 11 11 11 1 Bacteriophage T4 beta-glucosyltransferase RNA_pol_Rpa2_4 PF06883.12 RUS85766.1 - 0.0096 15.9 22.9 31 4.7 0.1 10.0 9 2 1 10 10 10 1 RNA polymerase I, Rpa2 specific domain DUF5005 PF16396.5 RUS85766.1 - 0.012 14.4 0.2 7.4 5.1 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5005) ATP-sulfurylase PF01747.17 RUS85766.1 - 0.34 10.3 0.2 96 2.3 0.0 4.0 2 1 2 4 4 4 0 ATP-sulfurylase YkpC PF17447.2 RUS85767.1 - 2.5e-19 67.6 0.0 3.9e+02 2.3 0.0 16.3 17 0 0 17 17 17 0 Uncharacterized YkpC-like GSu_C4xC__C2xCH PF09698.10 RUS85767.1 - 0.0051 17.6 45.8 1.6e+02 3.1 0.0 16.0 17 0 0 17 17 17 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) GluR_Homer-bdg PF10606.9 RUS85767.1 - 0.0082 16.3 11.1 52 4.2 0.2 5.5 1 1 9 10 10 10 0 Homer-binding domain of metabotropic glutamate receptor SNN_cytoplasm PF09051.10 RUS85767.1 - 0.15 11.9 0.1 19 5.2 0.1 5.0 1 0 0 1 1 1 0 Stannin cytoplasmic zinc-ribbons_6 PF07191.12 RUS85767.1 - 6.9 6.7 20.1 79 3.3 1.4 5.2 1 1 3 4 4 4 0 zinc-ribbons Nbas_N PF15492.6 RUS85771.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Integrase_H2C2 PF17921.1 RUS85773.1 - 1e-15 57.6 0.1 1.6e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RUS85773.1 - 9.9e-05 22.5 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger CUB PF00431.20 RUS85774.1 - 5.5e-59 197.3 2.8 1.1e-29 103.0 0.1 2.5 3 0 0 3 3 3 2 CUB domain CUB_2 PF02408.20 RUS85774.1 - 0.016 14.9 1.2 3.7 7.3 0.2 2.6 2 1 0 2 2 2 0 CUB-like domain DUF773 PF05600.12 RUS85775.1 - 4.8e-27 94.9 1.0 5.3e-27 94.7 1.0 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 SlyX PF04102.12 RUS85776.1 - 0.0011 19.6 19.9 0.062 13.9 0.8 5.1 4 3 1 5 5 4 2 SlyX DUF3584 PF12128.8 RUS85776.1 - 0.0045 14.6 19.0 0.0061 14.2 19.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ERM PF00769.19 RUS85776.1 - 0.076 12.8 25.8 0.23 11.2 25.8 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 RUS85776.1 - 0.081 12.9 27.1 0.24 11.4 0.8 5.0 3 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 RUS85776.1 - 0.12 11.7 28.7 0.11 11.9 7.4 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HDV_ag PF01517.18 RUS85776.1 - 0.15 11.9 12.7 0.015 15.1 6.9 2.1 1 1 2 3 3 3 0 Hepatitis delta virus delta antigen SLATT_4 PF18186.1 RUS85776.1 - 0.27 10.9 5.8 6.3 6.4 0.8 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF5082 PF16888.5 RUS85776.1 - 0.41 10.9 19.0 0.098 12.9 5.7 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) P4Ha_N PF08336.11 RUS85776.1 - 0.49 10.4 18.1 0.88 9.6 2.9 4.0 4 0 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region YabA PF06156.13 RUS85776.1 - 0.53 11.0 16.6 1.4 9.6 1.3 4.2 2 1 1 3 3 3 0 Initiation control protein YabA SHE3 PF17078.5 RUS85776.1 - 0.71 9.5 24.9 2.8 7.6 11.9 3.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 RB_B PF01857.20 RUS85776.1 - 0.91 9.6 4.2 1.7 8.7 0.5 2.8 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain DUF1192 PF06698.11 RUS85776.1 - 1 9.4 6.3 10 6.2 0.4 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 RUS85776.1 - 2.1 8.7 22.3 3.3 8.1 4.8 4.6 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) DUF745 PF05335.13 RUS85776.1 - 2.7 7.7 12.4 0.66 9.7 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF745) PKcGMP_CC PF16808.5 RUS85776.1 - 3.1 7.7 32.6 0.14 12.1 1.7 5.7 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2730 PF10805.8 RUS85776.1 - 3.2 7.9 15.8 14 5.8 0.3 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 RUS85776.1 - 3.6 7.8 24.2 0.021 15.0 4.3 4.1 3 2 2 6 6 5 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 RUS85776.1 - 3.9 7.3 24.3 0.074 12.9 7.2 4.1 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 1 NYD-SP28_assoc PF14775.6 RUS85776.1 - 5.8 7.1 10.1 0.19 11.9 1.2 3.1 3 0 0 3 3 2 0 Sperm tail C-terminal domain Adhesin_P1_N PF18652.1 RUS85776.1 - 6.7 6.8 6.3 1.1 9.3 0.6 2.6 3 0 0 3 3 2 0 Adhesin P1 N-terminal domain Nup54_57_C PF18570.1 RUS85776.1 - 7.8 6.2 10.3 4.7 6.9 0.0 3.9 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain B12D PF06522.11 RUS85777.1 - 1e-19 70.1 0.1 1.2e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX7a PF02238.15 RUS85777.1 - 0.092 13.2 0.2 0.14 12.6 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII LSDAT_euk PF18139.1 RUS85778.1 - 5.4e-80 268.6 0.3 7.8e-80 268.1 0.3 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 RUS85778.1 - 1.2e-28 99.7 0.4 2.1e-28 98.9 0.4 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote LDcluster4 PF18306.1 RUS85778.1 - 0.0058 16.2 1.7 0.86 9.2 0.6 2.3 2 0 0 2 2 2 2 SLOG cluster4 family NID PF07292.13 RUS85778.1 - 0.012 16.2 0.1 0.043 14.5 0.1 1.9 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) WXG100 PF06013.12 RUS85779.1 - 0.015 15.5 1.3 0.029 14.6 1.3 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DELLA PF12041.8 RUS85779.1 - 3.3 7.7 5.1 46 4.0 5.0 2.4 1 1 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF148 PF02520.17 RUS85779.1 - 7 6.8 11.3 0.55 10.4 4.4 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF148 AcylCoA_dehyd_C PF12186.8 RUS85779.1 - 9 6.5 8.3 0.21 11.7 1.2 1.9 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal TSP_1 PF00090.19 RUS85782.1 - 6.7e-08 32.6 23.2 2.9e-05 24.2 6.5 2.8 2 1 0 2 2 2 2 Thrombospondin type 1 domain EF-hand_1 PF00036.32 RUS85783.1 - 1.3e-28 96.4 3.4 5.6e-07 28.7 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS85783.1 - 5.3e-27 94.1 1.3 3.5e-15 56.2 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS85783.1 - 2e-25 86.5 4.6 3.3e-07 29.7 0.4 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS85783.1 - 1.3e-20 71.9 9.4 5e-07 28.9 0.7 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RUS85783.1 - 1.9e-14 53.2 7.9 2.3e-09 37.0 0.4 3.9 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS85783.1 - 1.2e-07 32.1 0.2 5.7e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 RUS85783.1 - 2.1e-07 31.2 0.0 0.0091 16.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 RUS85783.1 - 0.00032 20.5 6.0 1.6 8.6 0.3 4.0 3 1 1 4 4 4 2 EF hand EF-hand_4 PF12763.7 RUS85783.1 - 0.00055 19.8 0.9 0.005 16.8 0.2 2.2 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS85783.1 - 0.0026 17.7 0.9 3.5 7.5 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein DUF1456 PF07308.13 RUS85783.1 - 0.013 15.8 0.1 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Vps23_core PF09454.10 RUS85783.1 - 0.013 15.4 0.0 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 Vps23 core domain RNA_pol_Rpb4 PF03874.16 RUS85783.1 - 0.063 13.6 0.2 0.17 12.3 0.2 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb4 DUF1133 PF06576.11 RUS85783.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) FAD_binding_5 PF00941.21 RUS85783.1 - 0.095 12.4 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase HNH_2 PF13391.6 RUS85784.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease 7tm_1 PF00001.21 RUS85785.1 - 5.2e-06 26.0 14.2 0.0013 18.1 0.3 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS85785.1 - 1.1e-05 25.2 12.9 1.1e-05 25.2 12.9 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS85785.1 - 2.1e-05 24.0 14.7 3.1e-05 23.4 0.6 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Herpes_US9 PF06072.11 RUS85785.1 - 3.1 7.8 7.6 16 5.5 0.0 3.8 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Sushi PF00084.20 RUS85786.1 - 4e-62 206.6 75.2 3.2e-07 30.8 0.5 14.6 13 2 1 14 14 14 12 Sushi repeat (SCR repeat) HRM PF02793.22 RUS85786.1 - 0.00027 21.2 63.8 0.1 12.9 0.8 10.8 12 0 0 12 12 12 7 Hormone receptor domain PAN_1 PF00024.26 RUS85786.1 - 0.0045 16.9 0.1 0.015 15.2 0.1 1.9 1 0 0 1 1 1 1 PAN domain Sushi PF00084.20 RUS85787.1 - 2.4e-45 152.9 52.9 2.5e-07 31.2 1.0 8.5 8 1 0 8 8 8 8 Sushi repeat (SCR repeat) HRM PF02793.22 RUS85787.1 - 0.0011 19.2 44.6 0.84 10.0 0.9 8.2 8 0 0 8 8 8 6 Hormone receptor domain Sushi PF00084.20 RUS85788.1 - 9.5e-38 128.6 26.2 1.2e-09 38.6 0.6 6.8 6 1 0 6 6 6 6 Sushi repeat (SCR repeat) HRM PF02793.22 RUS85788.1 - 0.0012 19.1 22.7 0.19 12.0 0.6 6.1 6 0 0 6 6 6 3 Hormone receptor domain cEGF PF12662.7 RUS85788.1 - 0.096 12.6 14.4 0.96 9.4 0.4 5.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like GST_C_3 PF14497.6 RUS85789.1 - 7.7e-22 77.4 0.1 1.2e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS85789.1 - 9.5e-14 51.5 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS85789.1 - 5.7e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS85789.1 - 7.4e-07 29.5 0.0 6.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS85789.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS85789.1 - 0.0081 16.9 0.0 0.024 15.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain C1-set PF07654.15 RUS85789.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain GST_N_2 PF13409.6 RUS85789.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Somatomedin_B PF01033.17 RUS85790.1 - 7.3e-07 29.5 6.3 2.6e-06 27.7 6.3 1.9 1 0 0 1 1 1 1 Somatomedin B domain Globin PF00042.22 RUS85791.1 - 2.5e-14 53.8 0.1 3.9e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Globin PDZ PF00595.24 RUS85792.1 - 5.3e-06 26.7 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS85792.1 - 4.7e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS85792.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Death PF00531.22 RUS85793.1 - 0.047 13.9 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Death domain RPA43_OB PF17875.1 RUS85795.1 - 0.015 15.9 0.2 0.75 10.4 0.0 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Mif2_N PF15624.6 RUS85795.1 - 0.037 14.7 2.1 0.037 14.7 2.1 1.9 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Afi1 PF07792.12 RUS85795.1 - 0.35 11.4 9.9 2.3 8.7 2.7 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BSP_II PF05432.11 RUS85795.1 - 0.5 10.0 25.3 0.084 12.6 12.3 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 RUS85795.1 - 0.95 8.7 20.5 0.19 11.1 1.5 2.2 2 0 0 2 2 2 0 BUD22 eIF-3c_N PF05470.12 RUS85795.1 - 1.1 7.5 8.2 0.63 8.3 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Prothymosin PF03247.14 RUS85795.1 - 1.6 9.2 42.0 0.36 11.3 9.5 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family MAM33 PF02330.16 RUS85795.1 - 2.9 7.8 15.7 6.5 6.6 7.8 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein Sigma70_ner PF04546.13 RUS85795.1 - 2.9 7.7 28.1 1.4 8.7 6.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region GRP PF07172.11 RUS85795.1 - 6.2 7.6 43.0 18 6.1 43.0 1.8 1 1 0 1 1 1 0 Glycine rich protein family COG6 PF06419.11 RUS85796.1 - 3.4e-198 659.8 3.1 4.5e-198 659.4 3.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RB_A PF01858.17 RUS85796.1 - 0.0016 18.3 3.0 0.013 15.4 0.1 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain Sec34 PF04136.15 RUS85796.1 - 0.013 15.4 2.5 0.013 15.4 2.5 2.5 3 0 0 3 3 3 0 Sec34-like family FCH PF00611.23 RUS85796.1 - 0.029 14.7 0.3 1.6 9.1 0.0 3.5 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain GyrB_insert PF18053.1 RUS85796.1 - 0.13 12.1 1.6 0.21 11.4 0.7 1.8 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain Muted PF14942.6 RUS85796.1 - 0.17 12.2 3.5 0.71 10.2 3.5 2.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4490 PF14892.6 RUS85797.1 - 6.3e-32 109.7 0.6 7e-32 109.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) 7tm_1 PF00001.21 RUS85798.1 - 1.9e-07 30.7 2.1 2.3e-07 30.4 2.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 RUS85798.1 - 0.00052 19.4 2.9 0.00092 18.6 2.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 RUS85798.1 - 0.0024 17.9 5.8 0.0029 17.6 0.1 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ocular_alb PF02101.15 RUS85798.1 - 1.8 7.4 9.2 0.56 9.1 4.0 2.2 2 1 0 2 2 2 0 Ocular albinism type 1 protein Peptidase_A22B PF04258.13 RUS85799.1 - 0.86 9.1 9.4 1.2 8.6 9.4 1.4 1 1 0 1 1 1 0 Signal peptide peptidase LIDHydrolase PF10230.9 RUS85800.1 - 1.2e-64 218.5 0.0 1.4e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 RUS85800.1 - 1.2e-05 26.0 0.0 1.6e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 RUS85800.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase MBOAT PF03062.19 RUS85801.1 - 3.6e-15 56.2 16.0 1.7e-14 54.0 16.0 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PsbJ PF01788.17 RUS85801.1 - 0.14 12.0 1.9 4.4 7.2 0.0 3.0 2 0 0 2 2 2 0 PsbJ zf-C2H2 PF00096.26 RUS85803.1 - 2.7e-08 33.8 17.5 0.0093 16.4 1.9 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS85803.1 - 2.6e-05 24.4 15.8 4.4e-05 23.7 1.6 4.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS85803.1 - 0.0011 19.7 12.7 0.59 11.1 1.5 4.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS85803.1 - 0.057 13.2 16.0 0.082 12.7 2.4 4.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NIP_1 PF08995.10 RUS85803.1 - 0.2 12.1 0.9 0.73 10.2 0.0 2.3 2 0 0 2 2 2 0 Necrosis inducing protein-1 BLM10_N PF16547.5 RUS85803.1 - 1.5 9.2 5.4 0.89 9.9 1.4 2.7 2 1 1 3 3 3 0 Proteasome-substrate-size regulator, N-terminal CAP PF00188.26 RUS85804.1 - 6.1e-20 72.3 0.7 1e-19 71.6 0.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LIM PF00412.22 RUS85806.1 - 2.5e-05 24.4 1.5 4.6e-05 23.6 1.5 1.5 1 0 0 1 1 1 1 LIM domain Folliculin PF11704.8 RUS85807.1 - 0.85 9.5 14.4 0.11 12.3 5.4 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport EPL1 PF10513.9 RUS85807.1 - 0.99 9.8 16.1 1.2 9.4 6.9 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like MCU PF04678.13 RUS85807.1 - 1.1 9.3 11.0 2.1 8.4 8.1 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CPSF100_C PF13299.6 RUS85807.1 - 7 6.8 11.3 6.7 6.9 5.4 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Adeno_E3 PF06040.11 RUS85807.1 - 7.8 6.7 11.1 6.5 6.9 0.8 2.8 2 1 0 2 2 2 0 Adenovirus E3 protein DNA_pol_phi PF04931.13 RUS85808.1 - 2.1e-08 32.8 27.4 2.8e-08 32.4 27.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RUS85808.1 - 0.00083 17.7 25.1 0.00099 17.5 25.1 1.1 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.12 RUS85808.1 - 0.002 17.6 17.0 0.0027 17.1 17.0 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 RUS85808.1 - 0.0062 15.0 18.8 0.0079 14.7 18.8 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 RUS85808.1 - 0.02 13.2 20.7 0.028 12.7 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS85808.1 - 0.058 12.8 29.1 0.074 12.5 29.1 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 RUS85808.1 - 0.068 11.9 2.7 0.07 11.9 2.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 RUS85808.1 - 1.5 8.0 13.6 2.3 7.3 13.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 RUS85808.1 - 3.1 6.8 23.1 4 6.5 23.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-I PF07778.11 RUS85808.1 - 3.2 6.4 0.0 3.2 6.4 0.0 2.3 2 1 0 2 2 1 0 Mis6 IFT57 PF10498.9 RUS85808.1 - 4.6 6.1 10.5 7.2 5.5 10.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CNDH2_C PF16858.5 RUS85808.1 - 4.6 7.0 12.9 7 6.4 12.9 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop25 PF09805.9 RUS85808.1 - 9.2 6.7 13.5 15 6.1 13.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SLY PF12485.8 RUS85809.1 - 2.1 9.0 9.5 0.21 12.3 2.6 2.1 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Cadherin PF00028.17 RUS85810.1 - 6.1e-19 68.3 0.2 1e-17 64.4 0.0 2.7 3 0 0 3 3 3 1 Cadherin domain DUF2218 PF09981.9 RUS85810.1 - 0.0091 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) Cadherin PF00028.17 RUS85811.1 - 1.5e-83 275.4 17.8 6.6e-20 71.4 0.0 6.2 6 1 0 6 6 6 5 Cadherin domain Cadherin_3 PF16184.5 RUS85811.1 - 2.7e-12 46.7 9.9 0.082 12.9 0.2 6.1 6 0 0 6 6 6 5 Cadherin-like Cadherin_2 PF08266.12 RUS85811.1 - 2e-07 30.8 0.0 0.048 13.5 0.0 5.1 5 1 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 RUS85811.1 - 0.00076 19.8 0.0 4.2 7.7 0.0 3.5 3 0 0 3 3 3 1 RET Cadherin like domain 1 RET_CLD4 PF17813.1 RUS85811.1 - 0.0026 18.0 0.2 0.015 15.6 0.0 2.4 3 0 0 3 3 3 1 RET Cadherin like domain 4 Cadherin_pro PF08758.11 RUS85811.1 - 0.0084 16.2 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Cadherin prodomain like TFIIIC_sub6 PF10419.9 RUS85811.1 - 0.017 15.0 0.4 0.19 11.6 0.1 2.4 1 1 1 2 2 2 0 TFIIIC subunit triple barrel domain SUKH-4 PF14435.6 RUS85811.1 - 0.032 14.3 0.6 0.23 11.5 0.1 2.5 2 0 0 2 2 2 0 SUKH-4 immunity protein Rep_fac-A_3 PF08661.11 RUS85811.1 - 0.046 14.1 1.1 4.7 7.6 0.0 3.6 3 1 1 4 4 4 0 Replication factor A protein 3 Cadherin PF00028.17 RUS85812.1 - 3.2e-25 88.4 2.8 3.8e-14 52.9 0.1 3.3 3 0 0 3 3 3 3 Cadherin domain Cadherin_4 PF17803.1 RUS85812.1 - 0.093 13.4 23.4 1.5 9.5 0.7 3.7 3 1 0 3 3 3 0 Bacterial cadherin-like domain Glyco_hydro_20 PF00728.22 RUS85813.1 - 6.2e-88 295.5 0.0 8.5e-88 295.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 RUS85813.1 - 2.2e-19 69.7 0.0 7.7e-19 67.9 0.0 1.9 3 0 0 3 3 3 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 RUS85813.1 - 4.9e-14 52.1 0.0 1.2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 RUS85813.1 - 1e-09 39.2 0.0 1.9e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 tRNA_m1G_MT PF01746.21 RUS85814.1 - 1.3e-16 60.9 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF2681 PF10883.8 RUS85815.1 - 0.0078 16.6 0.4 0.013 15.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) MLANA PF14991.6 RUS85815.1 - 0.018 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF2970 PF11174.8 RUS85815.1 - 0.055 13.3 2.3 0.098 12.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Syndecan PF01034.20 RUS85815.1 - 0.46 10.4 2.3 0.77 9.7 2.3 1.3 1 0 0 1 1 1 0 Syndecan domain PMP1_2 PF08114.11 RUS85815.1 - 1.2 8.9 5.1 0.43 10.4 2.5 1.6 2 0 0 2 2 2 0 ATPase proteolipid family PRD1_DD PF11087.8 RUS85815.1 - 2.7 7.7 7.0 5.3 6.8 7.0 1.4 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Sigma_reg_N PF13800.6 RUS85816.1 - 0.029 14.7 0.1 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF2024 PF09630.10 RUS85817.1 - 0.036 13.9 2.1 12 5.9 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF2024) MalF_P2 PF14785.6 RUS85817.1 - 0.088 12.8 0.4 0.25 11.4 0.4 1.7 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain F420_ligase PF01996.16 RUS85817.1 - 0.09 12.1 1.7 0.19 11.1 0.1 2.2 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase MORN PF02493.20 RUS85818.1 - 6.6 6.8 43.5 41 4.4 0.2 9.4 10 0 0 10 10 10 0 MORN repeat DUF2501 PF10696.9 RUS85819.1 - 0.035 14.4 2.0 0.048 13.9 0.8 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2501) PALP PF00291.25 RUS85820.1 - 2.7e-60 204.3 0.1 3.5e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Baculo_PEP_C PF04513.12 RUS85821.1 - 0.025 14.6 4.2 0.04 13.9 4.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 RUS85821.1 - 0.087 10.8 0.0 2.6 5.9 0.0 1.8 1 1 1 2 2 2 0 Prominin DUF844 PF05815.11 RUS85821.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) YcgL PF05166.13 RUS85821.1 - 0.1 12.9 0.0 34 4.9 0.0 3.6 1 1 1 2 2 2 0 YcgL domain HLH PF00010.26 RUS85822.1 - 2.1e-05 24.4 0.7 4.1e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2207 PF09972.9 RUS85822.1 - 0.0014 17.5 0.5 0.0022 16.8 0.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Prominin PF05478.11 RUS85822.1 - 0.0096 13.9 2.2 0.014 13.4 2.2 1.2 1 0 0 1 1 1 1 Prominin Death PF00531.22 RUS85822.1 - 0.012 15.7 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Death domain Orf78 PF06024.12 RUS85822.1 - 2.6 8.4 11.9 0.13 12.6 4.7 2.4 3 0 0 3 3 3 0 Orf78 (ac78) Ephrin_rec_like PF07699.13 RUS85823.1 - 2.6e-07 30.3 4.7 4.3e-07 29.6 4.7 1.4 1 0 0 1 1 1 1 Putative ephrin-receptor like NCD3G PF07562.14 RUS85823.1 - 0.0099 15.8 5.4 0.019 14.9 5.4 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS85823.1 - 0.25 11.8 5.7 0.095 13.1 1.8 2.1 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region CUB PF00431.20 RUS85826.1 - 1.2e-05 25.7 0.0 0.00013 22.3 0.0 2.0 1 1 0 1 1 1 1 CUB domain SRP72 PF08492.12 RUS85827.1 - 3.9 8.0 5.5 7.4 7.1 0.2 2.9 2 0 0 2 2 2 0 SRP72 RNA-binding domain SNF PF00209.18 RUS85828.1 - 2.9e-107 359.6 24.3 3.5e-107 359.3 24.3 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 RUS85829.1 - 8.8e-38 130.3 6.8 1.1e-37 130.0 6.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ZapB PF06005.12 RUS85829.1 - 0.067 13.6 0.4 0.094 13.2 0.4 1.2 1 0 0 1 1 1 0 Cell division protein ZapB DASH_Spc34 PF08657.10 RUS85829.1 - 0.1 12.4 0.5 0.13 12.1 0.5 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 UPF0184 PF03670.13 RUS85829.1 - 0.17 12.3 1.4 0.35 11.3 1.4 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) MtrB PF05440.12 RUS85829.1 - 0.19 12.2 0.1 0.3 11.5 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B TPR_2 PF07719.17 RUS85830.1 - 3.3e-24 83.0 20.1 0.0065 16.5 0.3 9.0 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 RUS85830.1 - 5.8e-24 82.9 18.6 0.00072 19.3 0.0 8.3 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85830.1 - 1.6e-23 82.8 17.7 5.7e-10 39.4 0.4 6.2 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 RUS85830.1 - 5e-21 73.1 13.9 0.0036 17.2 0.0 8.2 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85830.1 - 7e-15 53.9 25.0 0.12 12.6 0.1 9.3 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 RUS85830.1 - 1.6e-09 37.2 5.5 1.3 8.8 0.1 6.4 6 0 0 6 6 6 3 TPR repeat TPR_MalT PF17874.1 RUS85830.1 - 3.7e-09 36.4 1.6 3.3e-07 30.0 1.0 2.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 RUS85830.1 - 2.5e-08 34.1 6.6 2.4 9.2 0.0 7.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS85830.1 - 6.1e-08 32.5 4.3 9.7 6.8 0.0 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS85830.1 - 7e-08 32.9 8.7 0.74 10.4 0.1 5.8 2 2 4 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS85830.1 - 7.6e-08 32.5 7.2 0.02 15.1 0.1 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 RUS85830.1 - 1.9e-07 30.9 2.9 0.0029 17.3 0.1 4.2 3 1 1 4 4 4 1 26S proteasome subunit RPN7 DUF3856 PF12968.7 RUS85830.1 - 4.9e-07 29.9 4.4 0.0038 17.3 0.0 4.5 3 1 0 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 RUS85830.1 - 8.8e-07 29.5 8.4 0.88 10.3 0.5 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 RUS85830.1 - 9.3e-07 28.9 0.4 0.018 15.2 0.0 4.3 4 1 0 4 4 4 2 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 RUS85830.1 - 1.1e-06 28.3 13.4 0.018 14.9 0.0 6.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS85830.1 - 0.00013 22.4 11.0 7.7 7.4 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 RUS85830.1 - 0.00015 22.0 0.0 9.1 7.2 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat ParD_antitoxin PF03693.14 RUS85830.1 - 0.01 16.2 0.9 0.091 13.2 0.1 2.8 3 0 0 3 3 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH MIT PF04212.18 RUS85830.1 - 0.045 13.8 8.4 15 5.7 0.1 5.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 RUS85830.1 - 0.049 13.9 2.5 19 5.8 0.1 4.3 4 0 0 4 4 3 0 PPR repeat DUF357 PF04010.13 RUS85830.1 - 0.06 13.4 2.9 4.7 7.3 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF357) NRBF2_MIT PF17169.4 RUS85830.1 - 0.078 13.2 0.6 1.7 8.9 0.1 3.4 3 1 1 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 DUF2225 PF09986.9 RUS85830.1 - 0.11 12.2 3.6 2.5 7.8 0.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PhoU PF01895.19 RUS85830.1 - 0.21 12.1 4.7 0.3 11.6 0.3 2.9 2 0 0 2 2 2 0 PhoU domain PNPase PF03726.14 RUS85830.1 - 0.24 11.9 2.8 30 5.2 0.1 3.2 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TPR_3 PF07720.12 RUS85830.1 - 0.46 10.5 0.0 0.46 10.5 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 RUS85830.1 - 0.53 10.4 5.7 39 4.4 0.2 4.5 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 MA3 PF02847.17 RUS85831.1 - 1.1e-21 77.0 0.9 1.1e-21 77.0 0.9 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 RUS85831.1 - 1.5e-21 77.1 1.8 1.5e-21 77.1 1.8 2.4 2 0 0 2 2 2 1 MIF4G domain DUF919 PF06034.11 RUS85831.1 - 9.6 6.1 12.7 2.2 8.2 0.0 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TPR_19 PF14559.6 RUS85832.1 - 8.1e-05 23.0 4.8 5.9 7.5 0.0 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS85832.1 - 0.0019 18.1 0.6 0.34 11.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85832.1 - 0.0047 17.0 0.2 5 7.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3447 PF11929.8 RUS85832.1 - 0.015 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) TPR_2 PF07719.17 RUS85833.1 - 0.0012 18.7 4.6 0.1 12.8 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85833.1 - 0.0015 18.8 2.5 0.0015 18.8 2.5 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS85833.1 - 0.064 13.1 9.4 1 9.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85833.1 - 2 8.8 6.3 0.28 11.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 RUS85834.1 - 2.6e-14 53.3 0.1 5.8e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 RUS85834.1 - 0.00012 21.5 0.4 0.0002 20.8 0.0 1.5 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 RUS85834.1 - 0.00028 20.8 0.1 0.0017 18.3 0.1 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 RUS85834.1 - 0.00043 19.9 0.3 0.0013 18.3 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RUS85834.1 - 0.0069 16.4 0.1 0.94 9.5 0.0 2.5 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 RUS85834.1 - 0.03 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 RUS85834.1 - 0.051 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 RUS85834.1 - 0.064 12.3 0.1 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 RUS85834.1 - 0.075 12.6 0.1 9.5 5.7 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 RUS85834.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 RUS85834.1 - 0.13 11.9 0.1 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 RUS85834.1 - 0.16 11.6 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 RUS85834.1 - 0.16 11.1 0.7 0.29 10.2 0.0 1.8 3 0 0 3 3 3 0 G-protein alpha subunit Integrin_alpha2 PF08441.12 RUS85835.1 - 5.4e-52 177.2 0.1 8e-52 176.7 0.1 1.3 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 RUS85835.1 - 1.4e-19 69.9 12.1 3.8e-09 36.5 0.3 4.2 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 RUS85835.1 - 6.7e-11 42.6 2.8 9.8e-09 35.7 0.6 3.1 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 RUS85835.1 - 6.7e-05 23.1 16.1 0.12 12.7 0.0 5.2 5 0 0 5 5 5 3 FG-GAP repeat Integrin_alpha PF00357.20 RUS85835.1 - 0.31 11.1 3.8 0.94 9.6 3.8 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Vinculin PF01044.19 RUS85836.1 - 3.9e-283 942.3 39.8 1.9e-191 638.8 25.8 2.1 1 1 1 2 2 2 2 Vinculin family I_LWEQ PF01608.17 RUS85836.1 - 0.0065 16.7 3.8 0.0065 16.7 3.8 6.3 5 1 0 6 6 6 3 I/LWEQ domain GIT1_C PF12205.8 RUS85836.1 - 0.085 13.0 5.7 0.82 9.8 0.3 4.0 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Mobilization_B PF17511.2 RUS85836.1 - 1.1 9.6 9.5 2.3 8.6 0.5 4.0 3 1 1 4 4 4 0 Mobilization protein B DivIC PF04977.15 RUS85836.1 - 1.6 8.6 5.2 0.74 9.6 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator EF-G-binding_N PF07299.11 RUS85836.1 - 1.9 9.1 4.5 6.7 7.3 0.0 3.9 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal DUF1876 PF08962.11 RUS85836.1 - 3 7.9 11.5 0.85 9.6 0.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1876) CLZ PF16526.5 RUS85836.1 - 9 6.7 8.8 21 5.6 0.0 4.5 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-Di19 PF05605.12 RUS85837.1 - 2.2 8.7 3.9 1.3 9.4 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NHL PF01436.21 RUS85841.1 - 2.8e-29 99.6 2.0 2.9e-05 23.9 0.1 7.8 6 2 0 6 6 6 6 NHL repeat Thioredoxin_8 PF13905.6 RUS85841.1 - 8.8e-11 42.0 0.0 2.3e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Arylesterase PF01731.20 RUS85841.1 - 3.5e-05 23.9 0.0 0.07 13.3 0.0 3.7 4 0 0 4 4 4 1 Arylesterase Thioredoxin PF00085.20 RUS85841.1 - 6.7e-05 22.8 0.0 0.043 13.8 0.1 2.5 1 1 0 2 2 2 2 Thioredoxin SGL PF08450.12 RUS85841.1 - 0.0037 16.9 0.7 13 5.3 0.0 4.1 1 1 3 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region FlgD_ig PF13860.6 RUS85841.1 - 0.0044 16.8 0.3 20 5.1 0.0 3.7 3 0 0 3 3 3 2 FlgD Ig-like domain TRL PF13146.6 RUS85841.1 - 0.018 15.3 0.1 0.057 13.7 0.1 1.8 1 0 0 1 1 1 0 TRL-like protein family MRJP PF03022.16 RUS85841.1 - 0.18 11.1 0.2 6.1 6.1 0.0 2.7 2 1 0 2 2 2 0 Major royal jelly protein 7tm_1 PF00001.21 RUS85842.1 - 1.8e-18 66.8 10.2 1.8e-18 66.8 10.2 1.9 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS85842.1 - 0.0014 18.4 4.1 0.0018 18.1 4.1 1.1 1 0 0 1 1 1 1 Olfactory receptor SID-1_RNA_chan PF13965.6 RUS85842.1 - 0.023 13.1 2.5 0.034 12.6 2.5 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 TAS2R PF05296.13 RUS85842.1 - 1.1 8.3 12.7 2.1 7.4 7.2 2.0 1 1 1 2 2 2 0 Taste receptor protein (TAS2R) Sulfotransfer_1 PF00685.27 RUS85843.1 - 1.7e-15 57.2 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85843.1 - 9.4e-05 22.9 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sgf11 PF08209.11 RUS85843.1 - 0.049 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_5 PF13909.6 RUS85844.1 - 6.9e-17 60.9 22.0 1.4e-07 31.1 2.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS85844.1 - 7.3e-15 54.6 34.3 1.3e-07 31.7 1.3 5.9 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 RUS85844.1 - 1.1e-11 44.6 36.1 0.00019 21.7 5.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS85844.1 - 4.9e-08 33.2 31.8 0.011 16.5 0.3 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 RUS85844.1 - 0.00031 21.1 13.0 0.051 14.0 0.3 4.7 3 1 1 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 RUS85844.1 - 0.0051 17.1 15.6 1 9.7 0.1 3.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 RUS85844.1 - 0.15 12.0 8.2 0.029 14.3 2.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TRAF6_Z2 PF18048.1 RUS85844.1 - 0.26 11.4 4.8 1 9.5 4.8 2.0 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 RUS85844.1 - 0.44 10.9 15.3 8.8 6.7 0.0 3.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 RUS85844.1 - 0.48 10.1 9.0 0.83 9.3 0.3 3.0 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Elf1 PF05129.13 RUS85844.1 - 3.1 7.9 9.3 0.54 10.3 2.8 2.8 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like PI-PLC-X PF00388.19 RUS85845.1 - 3.4e-60 201.8 0.2 2.9e-59 198.8 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 RUS85845.1 - 7.4e-44 147.7 1.3 5.4e-23 80.9 0.4 3.0 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 RUS85845.1 - 4.6e-38 130.1 0.0 4.6e-38 130.1 0.0 2.2 3 0 0 3 3 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 RUS85845.1 - 1.8e-15 57.1 0.0 4.4e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 RUS85845.1 - 8.9e-15 54.0 0.2 2.7e-14 52.5 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS85845.1 - 1.6e-11 43.8 1.0 2.9e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 RUS85845.1 - 7e-09 36.1 1.2 0.0042 17.6 0.0 3.6 3 0 0 3 3 3 2 PH domain SH3_2 PF07653.17 RUS85845.1 - 3e-06 26.8 0.0 6.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_12 PF16457.5 RUS85845.1 - 6.5e-05 23.5 0.0 0.0015 19.0 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_7 PF13499.6 RUS85845.1 - 6.6e-05 23.3 1.1 0.00036 20.9 0.8 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS85845.1 - 0.00036 19.9 0.1 0.0015 18.0 0.1 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS85845.1 - 0.00083 19.1 0.0 0.0033 17.2 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain DUF5392 PF17370.2 RUS85845.1 - 0.053 13.6 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5392) EF-hand_like PF09279.11 RUS85845.1 - 0.12 12.9 1.2 0.28 11.7 0.3 2.2 2 0 0 2 2 1 0 Phosphoinositide-specific phospholipase C, efhand-like Prok-TraM PF09228.10 RUS85845.1 - 0.43 11.0 4.6 2.6 8.5 2.3 2.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Ribosomal_L7Ae PF01248.26 RUS85846.1 - 2e-25 88.3 0.1 2.2e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 RUS85846.1 - 0.00082 19.5 0.0 0.00092 19.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Sulfotransfer_1 PF00685.27 RUS85847.1 - 2.9e-51 174.5 0.1 1.9e-49 168.5 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85847.1 - 6e-05 23.5 0.0 9.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS85847.1 - 0.054 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS85848.1 - 4.3e-43 147.7 0.1 5.1e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS85848.1 - 0.00021 21.7 0.0 0.00032 21.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family ICMT PF04140.14 RUS85849.1 - 0.56 10.7 0.1 0.56 10.7 0.1 2.7 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Aminotran_3 PF00202.21 RUS85850.1 - 2.5e-85 286.6 0.0 4.3e-85 285.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III FAM176 PF14851.6 RUS85851.1 - 0.36 10.5 3.8 0.51 10.0 3.8 1.2 1 0 0 1 1 1 0 FAM176 family Slu7 PF11708.8 RUS85851.1 - 0.46 10.2 5.4 0.6 9.8 5.4 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor RXT2_N PF08595.11 RUS85851.1 - 1.8 8.5 9.4 2.6 8.0 9.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 RUS85851.1 - 4.9 5.3 8.5 6.5 4.9 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 RUS85851.1 - 8.1 6.0 7.9 12 5.4 7.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Utp14 PF04615.13 RUS85851.1 - 8.4 4.8 8.0 11 4.5 8.0 1.0 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 RUS85851.1 - 8.5 5.6 22.9 2.4 7.4 19.5 1.7 2 0 0 2 2 2 0 NOA36 protein Ndr PF03096.14 RUS85852.1 - 1.1e-93 313.0 0.0 4.1e-93 311.2 0.0 1.7 1 1 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 RUS85852.1 - 0.0048 16.6 0.1 0.027 14.1 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS85852.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PIN_11 PF18479.1 RUS85852.1 - 0.076 13.2 1.3 0.8 9.9 1.0 2.3 2 1 0 2 2 2 0 PIN like domain Thymosin PF01290.20 RUS85853.1 - 8e-05 22.3 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Thymosin beta-4 family REV1_C PF16727.5 RUS85853.1 - 0.034 14.5 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain LRR_8 PF13855.6 RUS85855.1 - 1.4e-12 47.1 7.8 2.4e-06 27.2 3.9 4.5 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 RUS85855.1 - 8.5e-06 26.0 8.3 0.0048 17.3 1.5 4.4 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS85855.1 - 0.0032 17.4 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS85855.1 - 0.004 17.5 7.7 5.8 7.9 0.1 5.7 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 RUS85855.1 - 0.23 11.6 7.2 5.9 7.2 0.4 4.6 4 0 0 4 4 4 0 Leucine Rich repeat DDE_Tnp_IS1595 PF12762.7 RUS85856.1 - 2.4e-19 69.9 0.0 5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.6 RUS85856.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 DDE superfamily endonuclease PIF1 PF05970.14 RUS85857.1 - 2.2e-88 296.9 0.0 2.7e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 RUS85857.1 - 2.1e-07 30.8 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS85857.1 - 0.048 13.9 0.2 0.36 11.1 0.0 2.4 1 1 2 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 RUS85857.1 - 0.11 12.2 1.4 0.63 9.7 0.1 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DSL PF01414.19 RUS85858.1 - 0.003 17.8 33.3 0.0045 17.2 12.2 2.2 2 0 0 2 2 2 2 Delta serrate ligand DEFB136 PF17333.2 RUS85858.1 - 0.0063 16.4 7.0 0.6 10.1 0.7 2.5 2 0 0 2 2 2 2 Beta defensin 136 TIL PF01826.17 RUS85858.1 - 0.032 14.5 28.0 0.4 11.0 7.7 2.3 1 1 2 3 3 3 0 Trypsin Inhibitor like cysteine rich domain AFG1_ATPase PF03969.16 RUS85860.1 - 2e-108 362.5 0.0 2.2e-104 349.2 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 RUS85860.1 - 7.6e-06 25.9 0.6 0.038 13.8 0.1 3.3 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_16 PF13191.6 RUS85860.1 - 0.0015 18.9 0.0 0.065 13.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RUS85860.1 - 0.012 16.0 0.1 0.35 11.3 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS85860.1 - 0.021 15.1 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mrx7 PF10906.8 RUS85860.1 - 0.039 14.2 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 MIOREX complex component 7 Sigma_reg_C PF13791.6 RUS85860.1 - 0.11 12.7 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator C-terminal WhiA_N PF10298.9 RUS85860.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain TniB PF05621.11 RUS85860.1 - 0.16 11.3 0.4 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 RUS85861.1 - 6.5e-41 139.9 0.0 1.2e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RUS85861.1 - 8.6e-27 92.9 0.0 6e-26 90.2 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 RUS85861.1 - 8.4e-24 83.4 4.9 8.4e-24 83.4 4.9 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RUS85861.1 - 2.9e-08 33.4 0.0 8.6e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RUS85861.1 - 1.1e-05 25.4 0.0 3.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS85861.1 - 3.8e-05 24.1 0.2 0.0043 17.5 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 RUS85861.1 - 6.1e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 RUS85861.1 - 6.7e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 RUS85861.1 - 7.2e-05 23.1 0.5 0.005 17.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 RUS85861.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 RUS85861.1 - 0.00029 20.1 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 RUS85861.1 - 0.00039 20.6 0.1 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RUS85861.1 - 0.0014 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS85861.1 - 0.0015 19.1 0.1 0.009 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RUS85861.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS85861.1 - 0.0097 15.4 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 RUS85861.1 - 0.015 14.9 0.3 0.21 11.2 0.1 2.2 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RUS85861.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RUS85861.1 - 0.021 15.2 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 RUS85861.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 RUS85861.1 - 0.052 12.9 0.3 6.1 6.1 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.6 RUS85861.1 - 0.055 13.2 0.4 0.2 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS85861.1 - 0.075 12.9 0.0 0.78 9.6 0.0 2.2 1 1 2 3 3 3 0 NACHT domain TPR_1 PF00515.28 RUS85861.1 - 0.11 12.3 1.1 0.28 11.1 0.2 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS85861.1 - 0.13 12.5 2.1 0.37 11.0 0.5 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Sigma54_activat PF00158.26 RUS85861.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 RUS85861.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RUS85861.1 - 0.14 12.1 0.4 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RT_RNaseH_2 PF17919.1 RUS85862.1 - 8.4e-30 102.8 0.0 2.5e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS85862.1 - 4.5e-27 94.4 0.0 1.1e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS85862.1 - 1.2e-21 77.2 0.0 3.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS85862.1 - 1.7e-16 60.0 0.2 1.4e-15 57.2 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RUS85862.1 - 1.8e-06 28.0 0.1 8e-06 26.0 0.1 2.3 1 0 0 1 1 1 1 H2C2 zinc finger Glyco_hydro_79n PF03662.14 RUS85863.1 - 2.1e-07 30.2 0.0 3.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain UvrB_inter PF17757.1 RUS85863.1 - 0.068 13.4 0.0 7.4 6.8 0.0 2.7 1 1 1 2 2 2 0 UvrB interaction domain GP88 PF17338.2 RUS85867.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Gene product 88 GP88 PF17338.2 RUS85868.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Gene product 88 DUF4892 PF16234.5 RUS85869.1 - 0.00019 21.0 4.5 18 4.7 0.1 4.7 1 1 7 8 8 8 6 Domain of unknown function (DUF4892) Ribosomal_L2 PF00181.23 RUS85869.1 - 0.031 14.3 1.0 26 4.9 0.0 4.4 1 1 6 7 7 7 0 Ribosomal Proteins L2, RNA binding domain KCT2 PF17818.1 RUS85869.1 - 2.9 8.0 5.4 1.9e+02 2.0 0.2 4.1 1 1 4 6 6 6 0 Keratinocyte-associated gene product Tombus_P19 PF03220.13 RUS85869.1 - 4.2 7.0 16.3 17 5.0 2.0 3.7 1 1 4 5 5 5 0 Tombusvirus P19 core protein MFS_1 PF07690.16 RUS85870.1 - 1.9e-13 50.1 35.8 1.5e-07 30.7 6.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS85870.1 - 2.8e-08 33.1 21.5 1.3e-05 24.2 6.9 3.6 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 RUS85870.1 - 0.09 11.6 0.0 0.09 11.6 0.0 2.9 2 1 0 3 3 3 0 MFS_1 like family UQ_con PF00179.26 RUS85871.1 - 3.2e-49 166.2 0.0 3.6e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS85871.1 - 0.02 15.2 0.1 0.029 14.7 0.1 1.4 1 1 0 1 1 1 0 RWD domain Ribosomal_L6e PF01159.19 RUS85872.1 - 2.7e-41 140.6 1.3 4.7e-41 139.8 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e SPX PF03105.19 RUS85873.1 - 0.13 12.2 14.1 0.24 11.3 14.1 1.4 1 1 0 1 1 1 0 SPX domain SRP-alpha_N PF04086.13 RUS85873.1 - 0.15 11.9 9.8 0.2 11.6 9.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LCD1 PF09798.9 RUS85873.1 - 4.3 5.7 6.4 4.8 5.6 6.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein VPS9 PF02204.18 RUS85874.1 - 5e-17 62.0 0.0 1.1e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MIF PF01187.18 RUS85875.1 - 2.9e-21 75.9 0.0 3.1e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 RUS85875.1 - 0.035 14.0 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Tautomerase enzyme IFT20 PF14931.6 RUS85876.1 - 1.1e-48 164.3 10.3 1.2e-48 164.1 10.3 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 LepB_N PF18640.1 RUS85876.1 - 0.046 13.3 2.1 0.059 13.0 2.1 1.1 1 0 0 1 1 1 0 LepB N-terminal domain DUF737 PF05300.11 RUS85876.1 - 0.068 13.5 5.1 0.086 13.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TMPIT PF07851.13 RUS85876.1 - 0.57 9.4 6.3 0.67 9.1 6.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 RUS85876.1 - 2.2 8.4 9.3 6.1 7.0 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ion_trans_2 PF07885.16 RUS85878.1 - 3.4e-27 94.2 22.7 6e-15 55.0 0.9 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS85878.1 - 1.2e-07 31.2 8.9 8.8e-05 21.9 0.3 2.3 2 0 0 2 2 2 2 Ion transport protein Pex14_N PF04695.13 RUS85878.1 - 0.033 14.9 0.2 0.096 13.3 0.2 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NDUF_B7 PF05676.13 RUS85878.1 - 0.058 13.1 2.1 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3357 PF11837.8 RUS85878.1 - 0.15 12.5 0.8 0.63 10.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.6 RUS85878.1 - 0.58 10.6 2.3 0.83 10.1 0.0 2.2 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 RUS85878.1 - 0.8 8.9 7.9 5.6 6.1 7.9 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter GDPD PF03009.17 RUS85879.1 - 3.7e-24 85.8 0.0 4.8e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 RUS85879.1 - 0.075 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF5402 PF17393.2 RUS85879.1 - 0.11 12.5 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5402) Prp19 PF08606.11 RUS85880.1 - 1.6e-33 114.5 1.9 3.7e-33 113.3 1.9 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 RUS85880.1 - 3.4e-20 72.0 6.0 1.2e-05 26.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat U-box PF04564.15 RUS85880.1 - 4.3e-07 30.0 0.0 9.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain ANAPC4_WD40 PF12894.7 RUS85880.1 - 2.1e-06 27.9 0.1 0.029 14.7 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 RUS85880.1 - 0.00033 20.4 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.8 RUS85880.1 - 0.056 12.1 0.0 0.33 9.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Herpes_UL25 PF01499.16 RUS85880.1 - 0.061 11.8 0.9 0.083 11.4 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Pro_dh PF01619.18 RUS85881.1 - 9.3e-59 199.4 0.0 1.1e-58 199.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF229 PF02995.17 RUS85884.1 - 4e-96 322.6 2.8 5.1e-96 322.2 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS85884.1 - 0.00061 19.3 0.2 0.0031 17.0 0.0 1.9 1 1 1 2 2 2 1 Sulfatase SAM_decarbox PF01536.16 RUS85884.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Neur_chan_LBD PF02931.23 RUS85885.1 - 2.2e-25 89.4 0.2 3.6e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS85885.1 - 4.5e-18 66.2 6.6 5.8e-17 62.6 6.6 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region EMP70 PF02990.16 RUS85885.1 - 0.024 13.3 2.6 0.038 12.7 2.6 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 zf-H2C2_5 PF13909.6 RUS85886.1 - 1.5e-12 47.0 23.4 1.3e-05 24.8 0.2 5.0 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS85886.1 - 2.9e-07 30.6 4.7 0.00012 22.3 0.2 7.0 7 1 1 8 8 8 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS85886.1 - 5.6e-07 29.9 41.5 0.082 13.8 0.7 8.2 7 1 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS85886.1 - 6.1e-06 26.4 54.9 0.013 15.9 2.0 8.9 8 1 1 9 9 9 5 Zinc finger, C2H2 type DUF678 PF05077.12 RUS85886.1 - 0.0047 17.0 1.8 0.0047 17.0 1.8 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF678) zf_C2H2_ZHX PF18387.1 RUS85886.1 - 0.46 10.2 15.1 0.61 9.8 1.1 3.9 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain YbaB_DNA_bd PF02575.16 RUS85886.1 - 0.56 10.5 9.6 6.3 7.1 1.6 2.7 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Mucin PF01456.17 RUS85886.1 - 0.99 9.4 7.5 2.2 8.3 7.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-met PF12874.7 RUS85886.1 - 1.1 9.8 22.9 15 6.2 0.2 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type AAA_23 PF13476.6 RUS85887.1 - 0.048 14.2 4.1 0.031 14.8 1.0 2.1 2 0 0 2 2 2 0 AAA domain GAS2 PF02187.17 RUS85888.1 - 8.2e-31 105.9 0.1 1.7e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 RUS85888.1 - 1.4e-09 38.1 0.1 1.3e-07 31.8 0.1 2.3 1 1 0 1 1 1 1 Calponin homology (CH) domain Dynactin PF12455.8 RUS85888.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynein associated protein TNF PF00229.18 RUS85889.1 - 6.3e-14 52.0 0.0 9.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Death PF00531.22 RUS85890.1 - 0.036 14.2 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Death domain PknG_TPR PF16918.5 RUS85890.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat DUF1431 PF07248.12 RUS85894.1 - 0.27 11.5 4.4 5.3 7.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1431) Ig_3 PF13927.6 RUS85895.1 - 8.5e-87 285.8 10.4 2.7e-14 53.5 0.7 9.8 10 0 0 10 10 10 8 Immunoglobulin domain I-set PF07679.16 RUS85895.1 - 4.4e-79 260.6 0.0 1.8e-12 47.1 0.0 8.6 8 0 0 8 8 8 8 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS85895.1 - 2.4e-65 216.8 1.2 4.1e-08 33.4 0.0 8.5 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 RUS85895.1 - 2.1e-53 178.5 4.1 5e-08 33.0 0.0 10.0 10 0 0 10 10 9 8 Immunoglobulin domain fn3 PF00041.21 RUS85895.1 - 1.9e-40 137.1 20.4 1.5e-14 54.1 1.9 5.1 6 0 0 6 6 4 4 Fibronectin type III domain V-set PF07686.17 RUS85895.1 - 3.3e-30 104.5 13.2 3.9e-05 23.8 0.1 12.9 9 5 1 10 10 9 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS85895.1 - 2.6e-17 62.7 4.7 0.0065 16.5 0.1 8.0 8 0 0 8 8 8 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS85895.1 - 2.2e-09 36.7 0.0 1.9 8.1 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin domain C1-set PF07654.15 RUS85895.1 - 1.2e-08 35.2 2.7 0.00072 19.9 0.0 6.0 5 1 0 5 5 5 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 RUS85895.1 - 1.8e-05 24.9 0.0 3.2 8.1 0.0 5.9 6 0 0 6 6 5 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS85895.1 - 0.00011 22.2 0.0 3.7 7.7 0.0 5.1 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Interfer-bind PF09294.10 RUS85895.1 - 0.004 17.5 0.1 0.35 11.2 0.0 3.3 4 0 0 4 4 3 1 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.11 RUS85895.1 - 0.005 16.8 0.0 31 4.6 0.0 5.1 6 0 0 6 6 6 0 CD47 immunoglobulin-like domain Pur_ac_phosph_N PF16656.5 RUS85895.1 - 0.016 15.8 14.8 0.049 14.2 0.6 4.6 5 0 0 5 5 4 0 Purple acid Phosphatase, N-terminal domain C2-set PF05790.15 RUS85895.1 - 0.016 15.4 0.1 4.7 7.5 0.0 4.4 5 0 0 5 5 4 0 Immunoglobulin C2-set domain Arylsulfotran_N PF17425.2 RUS85895.1 - 0.11 12.6 0.2 2.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Arylsulfotransferase Ig-like domain fn3_2 PF16893.5 RUS85895.1 - 0.14 12.3 1.8 2 8.7 0.0 3.4 4 0 0 4 4 3 0 Fibronectin type III domain Adeno_E3_CR1 PF02440.15 RUS85895.1 - 0.15 11.9 1.1 11 5.9 0.0 4.3 6 0 0 6 6 5 0 Adenovirus E3 region protein CR1 Ctr PF04145.15 RUS85896.1 - 3.4e-25 89.4 4.4 4.8e-25 88.9 4.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family FtsX PF02687.21 RUS85896.1 - 0.017 15.6 0.4 0.093 13.2 0.2 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF4229 PF14012.6 RUS85896.1 - 0.21 11.7 3.7 0.13 12.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) PHD_4 PF16866.5 RUS85897.1 - 0.077 13.1 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 RUS85898.1 - 5.2e-10 39.5 1.8 5.2e-10 39.5 1.8 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 RUS85898.1 - 1e-09 37.9 1.4 3.5e-09 36.2 1.4 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS85898.1 - 4.1e-08 32.9 2.5 1.6e-07 31.0 2.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS85898.1 - 1.1e-07 31.6 0.9 3.6e-07 29.9 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS85898.1 - 4.7e-07 30.0 1.2 4.7e-07 30.0 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS85898.1 - 5.7e-06 26.3 4.0 1.4e-05 25.0 2.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS85898.1 - 3.1e-05 23.8 0.4 9.5e-05 22.3 0.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS85898.1 - 0.0019 18.0 0.2 0.0051 16.6 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RUS85898.1 - 0.0021 17.6 0.5 0.0054 16.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF3408 PF11888.8 RUS85898.1 - 0.0058 16.8 6.0 0.0058 16.8 6.0 2.9 2 1 0 2 2 1 1 Protein of unknown function (DUF3408) zf-ANAPC11 PF12861.7 RUS85898.1 - 0.0059 16.6 2.3 0.015 15.3 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RUS85898.1 - 0.031 14.1 1.4 0.092 12.6 1.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 RUS85898.1 - 0.12 12.6 0.7 0.45 10.7 0.7 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 RUS85898.1 - 0.16 12.2 1.5 0.53 10.5 0.8 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 RUS85898.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.5 2 0 0 2 2 2 0 RING-like domain ADK_lid PF05191.14 RUS85898.1 - 2.9 7.9 5.3 1.1 9.3 0.1 3.1 4 0 0 4 4 2 0 Adenylate kinase, active site lid eIF3g PF12353.8 RUS85899.1 - 2.3e-42 144.3 0.4 2.3e-42 144.3 0.4 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 RUS85899.1 - 1.4e-20 72.8 0.0 2.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS85899.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_bind PF08675.11 RUS85899.1 - 0.094 12.8 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 RUS85899.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zip PF02535.22 RUS85900.1 - 7.1e-78 262.1 29.6 8.6e-78 261.9 7.7 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter SARAF PF06682.12 RUS85900.1 - 0.066 12.9 1.6 0.41 10.3 0.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FtsK_4TM PF13491.6 RUS85900.1 - 0.13 12.0 6.3 9.2 5.9 4.5 3.4 3 1 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE Ost4 PF10215.9 RUS85900.1 - 6.6 6.7 6.8 0.31 10.9 0.4 2.1 2 0 0 2 2 2 0 Oligosaccaryltransferase Ldl_recept_a PF00057.18 RUS85902.1 - 7.6e-21 74.1 39.5 9.2e-06 25.8 0.8 5.7 5 1 1 6 6 6 5 Low-density lipoprotein receptor domain class A Daxx PF03344.15 RUS85903.1 - 0.00017 21.6 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 Daxx N-terminal Rassf1C-interacting domain FANCI_HD2 PF14680.6 RUS85903.1 - 0.047 12.9 2.5 0.14 11.3 2.5 1.8 1 0 0 1 1 1 0 FANCI helical domain 2 Prefoldin_2 PF01920.20 RUS85903.1 - 1.7 8.6 9.6 0.78 9.7 1.5 3.4 3 0 0 3 3 3 0 Prefoldin subunit Tektin PF03148.14 RUS85904.1 - 1.7e-24 86.4 2.2 1.9e-24 86.1 2.2 1.1 1 0 0 1 1 1 1 Tektin family ApbE PF02424.15 RUS85904.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 ApbE family Vps51 PF08700.11 RUS85904.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.1 3 0 0 3 3 3 0 Vps51/Vps67 L31 PF09784.9 RUS85904.1 - 0.63 10.5 3.0 0.65 10.5 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Ras PF00071.22 RUS85905.1 - 4.4e-61 205.2 0.1 5.2e-61 205.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS85905.1 - 3.1e-32 111.3 0.0 4.9e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS85905.1 - 3e-13 49.6 0.0 4.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS85905.1 - 1.8e-05 24.3 0.0 0.00067 19.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS85905.1 - 4e-05 23.7 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS85905.1 - 0.00012 22.0 0.1 0.26 11.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RUS85905.1 - 0.00075 18.9 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 RUS85905.1 - 0.028 14.2 0.0 0.68 9.7 0.0 2.0 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 RUS85905.1 - 0.13 11.9 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 RUS85905.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RUS85905.1 - 0.17 12.1 0.0 0.65 10.3 0.0 1.9 2 1 1 3 3 3 0 AAA domain FtsJ PF01728.19 RUS85906.1 - 5.5e-26 91.7 0.0 1.9e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 RUS85906.1 - 0.084 10.9 0.1 0.13 10.3 0.1 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase TPR_2 PF07719.17 RUS85907.1 - 9.1e-24 81.6 14.8 0.0013 18.7 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 RUS85907.1 - 7.4e-22 76.2 19.2 3.9e-07 29.6 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 RUS85907.1 - 7.8e-16 57.5 19.7 0.0037 16.9 0.0 8.1 7 2 2 9 9 9 5 TPR repeat TPR_16 PF13432.6 RUS85907.1 - 4.9e-13 49.5 0.4 0.042 14.5 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RUS85907.1 - 1.4e-11 44.5 8.8 0.0022 18.3 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS85907.1 - 8.9e-11 41.8 6.5 0.43 10.8 0.5 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 RUS85907.1 - 1.4e-06 28.6 7.7 11 7.1 0.0 7.9 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS85907.1 - 9.7e-06 25.6 6.9 13 6.5 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS85907.1 - 5.4e-05 22.5 0.8 0.49 9.5 0.1 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS85907.1 - 6.6e-05 22.8 17.2 2.9 8.3 0.5 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS85907.1 - 0.00012 22.5 15.8 0.12 12.9 0.0 7.1 5 3 2 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS85907.1 - 0.002 18.3 11.6 0.12 12.6 2.6 3.8 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Com_YlbF PF06133.11 RUS85907.1 - 0.018 15.6 3.9 0.19 12.3 0.1 2.7 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA TPR_7 PF13176.6 RUS85907.1 - 0.22 11.6 13.4 4.9 7.4 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 RUS85907.1 - 0.5 10.1 5.2 0.8 9.4 0.1 3.2 2 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) FMO-like PF00743.19 RUS85908.1 - 1.4e-203 677.1 0.0 1.7e-203 676.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RUS85908.1 - 1.9e-20 73.3 0.0 1.4e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS85908.1 - 7.3e-13 48.4 0.0 9.4e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS85908.1 - 2.4e-10 40.1 0.0 1.2e-06 28.0 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RUS85908.1 - 2e-05 24.7 0.1 7.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RUS85908.1 - 0.0037 17.8 0.5 0.17 12.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RUS85908.1 - 0.0048 16.2 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 RUS85908.1 - 0.0067 16.4 0.5 0.82 9.7 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 RUS85908.1 - 0.017 14.7 0.2 9.3 5.7 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Peptidase_M17_N PF02789.17 RUS85908.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Shikimate_DH PF01488.20 RUS85908.1 - 0.033 14.3 0.0 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 RUS85908.1 - 0.056 13.1 0.6 1.2 8.8 0.0 3.0 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 RUS85908.1 - 0.16 10.6 0.2 0.93 8.1 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein ATP_bind_2 PF03668.15 RUS85908.1 - 0.23 10.7 0.3 5.6 6.2 0.2 2.1 2 0 0 2 2 2 0 P-loop ATPase protein family Phage_holin_2_1 PF04971.12 RUS85909.1 - 0.003 17.5 3.5 37 4.4 0.0 4.0 1 1 6 7 7 7 0 Bacteriophage P21 holin S TMEM89 PF15098.6 RUS85909.1 - 0.006 16.8 0.2 26 5.0 0.0 3.1 1 1 3 4 4 4 1 TMEM89 protein family Baculo_PEP_C PF04513.12 RUS85909.1 - 0.007 16.4 0.1 0.036 14.1 0.1 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CYSTM PF12734.7 RUS85909.1 - 0.014 15.7 17.7 1.8e+02 2.5 0.0 8.1 9 0 0 9 9 9 0 Cysteine-rich TM module stress tolerance LEDGF PF11467.8 RUS85909.1 - 0.024 14.2 7.9 4.8 6.8 0.6 3.1 1 1 2 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) HU-CCDC81_euk_2 PF18289.1 RUS85909.1 - 0.27 11.4 9.3 54 4.0 0.2 4.2 1 1 6 7 7 7 0 CCDC81 eukaryotic HU domain 2 DNA_pol_phi PF04931.13 RUS85910.1 - 0.012 13.8 43.1 0.015 13.5 43.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS85910.1 - 1.7 6.7 31.7 2.2 6.4 31.7 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS85910.1 - 4 6.7 22.2 5.2 6.4 22.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 RUS85910.1 - 4.9 5.3 25.3 6.6 4.9 25.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.9 RUS85910.1 - 5.6 7.4 14.1 7.9 7.0 14.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Mpp10 PF04006.12 RUS85910.1 - 7.4 4.9 24.1 9.2 4.6 24.1 1.0 1 0 0 1 1 1 0 Mpp10 protein CPSase_L_D2 PF02786.17 RUS85911.1 - 0.0099 15.4 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PI-PLC-X PF00388.19 RUS85911.1 - 0.15 11.7 1.7 0.41 10.2 0.4 2.1 2 1 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain ORC_WH_C PF18137.1 RUS85911.1 - 0.16 12.1 1.4 0.19 11.8 0.4 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal LAMTOR PF15454.6 RUS85911.1 - 0.16 12.6 7.2 3.1 8.5 0.0 3.6 4 0 0 4 4 4 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CFIA_Pcf11 PF11526.8 RUS85911.1 - 0.19 12.3 8.2 0.084 13.4 5.6 1.7 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 RNA_polI_A14 PF08203.11 RUS85911.1 - 0.53 11.1 4.7 1.2 9.9 2.2 2.3 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 RAP1 PF07218.11 RUS85911.1 - 1.2 7.3 7.5 1.7 6.8 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 RUS85911.1 - 1.8 8.3 7.6 0.96 9.1 4.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Dscam_C PF12355.8 RUS85912.1 - 3.8 8.5 6.6 15 6.5 2.4 2.1 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal RasGEF PF00617.19 RUS85913.1 - 1.3e-47 162.3 0.0 1.9e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RUS85913.1 - 1.9e-11 44.1 0.1 4.8e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF123 PF01986.16 RUS85914.1 - 0.00066 20.1 0.1 0.0011 19.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF123 Pkinase PF00069.25 RUS85915.1 - 1.9e-05 24.2 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 RUS85915.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 RUS85915.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase CBM_14 PF01607.24 RUS85916.1 - 2.4e-52 174.9 68.7 4.8e-10 39.5 3.8 6.2 6 0 0 6 6 6 6 Chitin binding Peritrophin-A domain Aminotran_1_2 PF00155.21 RUS85917.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II M11L PF11099.8 RUS85917.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11L like Aminotran_5 PF00266.19 RUS85919.1 - 1.1e-23 83.8 0.0 1.3e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RUS85919.1 - 6.9e-07 28.1 0.0 9.4e-07 27.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RUS85919.1 - 2.7e-05 23.5 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RUS85919.1 - 0.076 12.3 0.1 0.49 9.6 0.1 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M1 PF01433.20 RUS85920.1 - 4.9e-43 147.2 0.0 8.1e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RUS85920.1 - 1.5e-26 92.7 0.0 2.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RUS85920.1 - 1.2e-15 58.2 0.0 1.9e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pkinase PF00069.25 RUS85921.1 - 3.2e-10 39.8 0.0 1.4e-09 37.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85921.1 - 0.0015 17.9 0.0 0.016 14.5 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase DUF2992 PF11208.8 RUS85921.1 - 6.6 7.0 10.4 14 5.9 10.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) KAP PF05804.12 RUS85922.1 - 0 1196.7 18.1 0 1196.5 18.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 RUS85922.1 - 1.6e-08 34.3 7.9 0.42 10.7 0.0 6.7 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 RUS85922.1 - 0.006 16.3 0.0 0.037 13.8 0.0 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain Chordopox_A30L PF06015.12 RUS85922.1 - 0.013 15.3 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein NopRA1 PF16201.5 RUS85922.1 - 0.029 14.0 2.8 13 5.3 0.1 3.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 FPL PF09758.9 RUS85922.1 - 0.28 11.2 13.9 0.087 12.8 3.0 3.7 3 1 1 4 4 4 0 Uncharacterised conserved protein V-ATPase_H_C PF11698.8 RUS85922.1 - 6 7.0 12.2 0.96 9.6 0.6 4.1 3 1 1 5 5 5 0 V-ATPase subunit H Methyltransf_PK PF05891.12 RUS85923.1 - 1.4e-82 276.4 0.0 1.6e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RUS85923.1 - 4.6e-08 33.7 0.0 7.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS85923.1 - 2.5e-07 31.3 0.0 3.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS85923.1 - 6.8e-05 23.5 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 RUS85923.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.6 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 RUS85923.1 - 0.00055 19.8 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RUS85923.1 - 0.003 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 RUS85923.1 - 0.0096 15.2 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 RUS85923.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Bin3 PF06859.12 RUS85923.1 - 0.084 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Pkinase PF00069.25 RUS85924.1 - 8.8e-26 90.8 0.0 1e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85924.1 - 2.4e-16 59.8 0.0 2.8e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS85924.1 - 1e-05 25.0 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS85924.1 - 2.5e-05 23.2 0.0 3e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS85924.1 - 0.00096 18.6 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS85924.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RUS85924.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 RUS85924.1 - 0.21 11.1 0.1 0.24 11.0 0.1 1.1 1 0 0 1 1 1 0 RIO1 family 7TM_GPCR_Srw PF10324.9 RUS85925.1 - 3.9e-11 42.8 24.7 5.8e-11 42.2 24.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS85925.1 - 7.5e-10 38.6 22.6 7.5e-10 38.6 22.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS85925.1 - 5.4e-08 32.8 27.5 5.5e-08 32.8 26.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS85926.1 - 2.9e-11 43.2 29.6 2.9e-11 43.2 29.6 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 RUS85927.1 - 1.6e-17 63.5 11.0 1.6e-17 63.5 11.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SF3A2 PF16835.5 RUS85930.1 - 0.047 14.1 0.0 0.095 13.1 0.0 1.8 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) GTP_EFTU PF00009.27 RUS85931.1 - 5.6e-49 166.3 0.0 9.2e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RUS85931.1 - 2.8e-24 85.6 0.2 9.8e-24 83.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 RUS85931.1 - 4.6e-11 42.8 11.4 4.7e-10 39.6 11.4 2.2 1 1 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 RUS85931.1 - 1.2e-07 31.8 0.1 0.00095 19.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RUS85931.1 - 2.6e-05 24.5 0.3 0.00015 22.1 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 CUE PF02845.16 RUS85931.1 - 0.021 14.6 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 CUE domain AAA_22 PF13401.6 RUS85931.1 - 0.029 14.6 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RUS85931.1 - 0.064 12.8 0.1 0.79 9.2 0.0 2.4 1 1 1 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 RUS85931.1 - 0.091 13.0 0.4 16 5.7 0.0 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BACK PF07707.15 RUS85932.1 - 1.7e-21 76.2 0.8 1.7e-21 76.2 0.8 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS85932.1 - 4.2e-21 75.2 1.3 1.2e-20 73.8 0.2 2.3 2 1 1 3 3 3 1 BTB/POZ domain Kelch_6 PF13964.6 RUS85932.1 - 7.2e-11 42.0 2.5 8.7e-05 22.7 0.0 4.8 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.25 RUS85932.1 - 2.6e-08 33.3 0.7 0.00043 19.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 RUS85932.1 - 1.3e-07 31.2 0.8 0.65 10.1 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 RUS85932.1 - 1.9e-06 27.8 0.1 0.0022 17.9 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS85932.1 - 1.6e-05 25.0 3.6 0.26 11.6 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS85932.1 - 0.1 12.6 1.7 0.55 10.3 0.0 2.9 3 0 0 3 3 3 0 Kelch motif DUF4483 PF14825.6 RUS85933.1 - 7.7e-20 71.2 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Wx5_PLAF3D7 PF09688.10 RUS85933.1 - 0.013 15.5 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) ApoLp-III PF07464.11 RUS85934.1 - 0.00083 19.5 4.6 0.0012 18.9 2.2 2.3 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Pkinase PF00069.25 RUS85935.1 - 1e-67 228.3 0.0 1.4e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS85935.1 - 1.4e-41 142.5 0.0 2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RUS85935.1 - 3e-12 46.7 0.2 1e-11 45.0 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 RUS85935.1 - 2.5e-05 23.8 0.0 4.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like VCBS PF13517.6 RUS85936.1 - 2.2e-22 79.4 15.7 2.1e-10 41.0 5.3 5.6 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 RUS85936.1 - 2.5e-13 49.8 0.0 6.7e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 RUS85936.1 - 5.3e-12 45.6 0.8 0.0012 19.0 0.0 3.9 3 0 0 3 3 3 3 FG-GAP repeat B12D PF06522.11 RUS85937.1 - 0.025 14.3 0.6 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FGase PF05013.12 RUS85937.1 - 0.027 14.7 0.0 29 4.8 0.0 3.0 3 0 0 3 3 3 0 N-formylglutamate amidohydrolase zf-RING_5 PF14634.6 RUS85937.1 - 0.12 12.4 9.4 11 6.1 0.3 3.5 3 0 0 3 3 3 0 zinc-RING finger domain zf-C2H2_3 PF13878.6 RUS85937.1 - 2.7 7.9 7.4 60 3.6 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C3HC4_2 PF13923.6 RUS85937.1 - 6.2 6.8 11.7 40 4.2 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_1 PF00561.20 RUS85938.1 - 7.9e-13 48.6 0.3 1.4e-12 47.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS85938.1 - 8.4e-13 48.1 0.1 4.8e-11 42.4 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS85938.1 - 7.2e-09 36.6 0.2 1.5e-08 35.5 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RUS85938.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS85938.1 - 0.00052 19.6 0.0 0.0015 18.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 RUS85938.1 - 0.00097 19.0 0.0 0.97 9.2 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 RUS85938.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II CARD PF00619.21 RUS85939.1 - 3.5e-21 75.0 1.4 1.4e-10 41.0 0.3 2.4 2 0 0 2 2 2 2 Caspase recruitment domain CARD_2 PF16739.5 RUS85939.1 - 6.6e-08 32.4 0.2 0.00026 20.9 0.1 2.3 2 0 0 2 2 2 2 Caspase recruitment domain WD40 PF00400.32 RUS85940.1 - 2.7e-28 97.6 3.4 0.00039 21.2 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85940.1 - 3.7e-10 40.0 0.0 0.0054 17.0 0.0 4.0 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS85940.1 - 0.00041 19.8 0.1 0.015 14.7 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 RUS85940.1 - 0.048 12.6 0.1 15 4.4 0.0 3.5 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DHC_N1 PF08385.12 RUS85941.1 - 5.8e-128 428.0 0.5 9.3e-80 268.8 0.0 3.8 4 1 0 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RUS85941.1 - 1.3e-92 311.0 3.3 1.3e-92 311.0 3.3 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DUF960 PF06124.11 RUS85941.1 - 0.098 13.3 0.1 0.42 11.3 0.1 2.1 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) PHM7_cyt PF14703.6 RUS85941.1 - 0.2 11.9 1.4 1.3 9.3 0.2 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter GCP_C_terminal PF04130.13 RUS85942.1 - 9e-81 271.7 16.6 2.1e-80 270.5 15.1 2.1 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RUS85942.1 - 1.6e-74 251.3 2.0 1.6e-74 251.3 2.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal PEP-utilisers_N PF05524.13 RUS85942.1 - 0.77 9.9 3.1 1 9.6 0.5 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal NCA2 PF08637.10 RUS85943.1 - 0.0014 17.9 0.3 0.0018 17.5 0.3 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Muted PF14942.6 RUS85943.1 - 0.0073 16.7 0.7 0.012 15.9 0.7 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein tRNA-Thr_ED PF08915.11 RUS85943.1 - 0.0081 16.2 0.7 0.021 14.9 0.2 1.8 2 0 0 2 2 2 1 Archaea-specific editing domain of threonyl-tRNA synthetase DUF3349 PF11829.8 RUS85943.1 - 0.013 16.3 2.8 0.027 15.3 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) AlaDh_PNT_C PF01262.21 RUS85943.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TMEM138 PF14935.6 RUS85944.1 - 4.2e-44 150.0 12.3 4.2e-44 150.0 12.3 1.8 2 0 0 2 2 2 1 Transmembrane protein 138 TcpE PF12648.7 RUS85944.1 - 1.6 9.3 11.9 0.98 10.0 9.9 1.7 1 1 1 2 2 2 0 TcpE family Trypan_PARP PF05887.11 RUS85946.1 - 2.9 7.9 16.0 0.49 10.4 4.7 3.0 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) DUF5585 PF17823.1 RUS85949.1 - 1.5e-06 27.4 0.0 1.5e-06 27.4 0.0 2.8 2 1 1 3 3 3 1 Family of unknown function (DUF5585) DUF2201_N PF13203.6 RUS85949.1 - 0.059 13.0 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Putative metallopeptidase domain PAS_3 PF08447.12 RUS85950.1 - 7e-21 74.3 1.2 4.2e-20 71.8 0.1 2.7 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 RUS85950.1 - 7.3e-14 51.9 0.1 7.3e-14 51.9 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 RUS85950.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold DUF3417 PF11897.8 RUS85950.1 - 0.13 12.8 3.1 0.56 10.7 3.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) PAS PF00989.25 RUS85951.1 - 3.5e-12 46.3 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 RUS85951.1 - 0.0016 18.5 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 RUS85951.1 - 0.0022 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RUS85951.1 - 0.0089 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 RUS85951.1 - 0.034 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 PAS fold HLH PF00010.26 RUS85952.1 - 0.00019 21.3 1.0 0.00033 20.5 1.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_WhiA PF02650.14 RUS85952.1 - 0.019 15.3 0.1 0.037 14.4 0.1 1.4 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Nop14 PF04147.12 RUS85953.1 - 0.6 8.3 22.7 0.74 8.0 22.7 1.0 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 RUS85953.1 - 1.9 7.5 8.2 2.2 7.3 8.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Mpp10 PF04006.12 RUS85953.1 - 4.3 5.7 17.6 5.2 5.4 17.6 1.1 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 RUS85953.1 - 4.7 7.0 13.3 6.3 6.6 13.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2796 PF10986.8 RUS85953.1 - 9.5 6.2 8.2 14 5.6 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SNF2_N PF00176.23 RUS85954.1 - 1.4e-89 300.3 0.2 2e-89 299.8 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS85954.1 - 4e-07 30.4 0.0 9.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 RUS85954.1 - 0.00037 20.3 5.5 0.00037 20.3 5.5 3.2 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 RUS85954.1 - 0.0006 20.1 11.7 0.0006 20.1 11.7 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 RUS85954.1 - 0.0039 17.0 10.3 0.0039 17.0 10.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4150 PF13665.6 RUS85954.1 - 0.12 12.5 4.7 0.35 11.0 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) zf-RING_UBOX PF13445.6 RUS85954.1 - 0.6 10.2 14.7 0.022 14.8 8.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger DUF3456 PF11938.8 RUS85956.1 - 0.019 15.5 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Microtub_bind PF13931.6 RUS85956.1 - 7.7 6.9 7.0 27 5.1 0.2 3.1 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding TFIID_20kDa PF03847.13 RUS85957.1 - 5e-30 103.8 2.3 7.2e-30 103.3 2.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 RUS85957.1 - 8.3e-05 23.0 0.3 0.00021 21.7 0.3 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS85957.1 - 0.00016 21.9 0.5 0.00028 21.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RUS85957.1 - 0.0013 18.8 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 RUS85957.1 - 0.025 14.7 0.2 0.064 13.4 0.2 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold AP3D1 PF06375.11 RUS85958.1 - 0.12 12.5 9.6 0.14 12.4 9.6 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PPL5 PF18168.1 RUS85958.1 - 0.45 9.8 3.7 0.5 9.6 3.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 RUS85958.1 - 7.7 5.2 4.7 8.1 5.1 4.7 1.0 1 0 0 1 1 1 0 Presenilin CMS1 PF14617.6 RUS85959.1 - 1e-32 113.5 0.5 1.2e-32 113.2 0.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 RUS85959.1 - 1.2e-06 28.4 0.1 1.4e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase BTB_2 PF02214.22 RUS85960.1 - 4.2e-23 81.5 0.0 9.7e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 RUS85960.1 - 1.2e-14 54.2 29.0 1.7e-13 50.4 29.0 2.2 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS85960.1 - 1.3e-11 44.3 6.0 1.3e-11 44.3 6.0 2.8 3 0 0 3 3 3 1 Ion channel DUF4023 PF13215.6 RUS85962.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) adh_short_C2 PF13561.6 RUS85963.1 - 3e-60 203.7 0.1 3.5e-60 203.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS85963.1 - 2e-52 177.5 0.3 2.4e-52 177.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS85963.1 - 7.9e-12 45.4 0.4 1.1e-11 45.0 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 RUS85963.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DDE_3 PF13358.6 RUS85964.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SDA1 PF05285.12 RUS85964.1 - 0.0095 15.4 17.4 0.011 15.2 17.4 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS85964.1 - 0.024 12.9 17.5 0.027 12.7 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS85964.1 - 0.085 11.1 12.5 0.087 11.1 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RUS85964.1 - 0.28 9.2 31.6 0.36 8.9 31.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RUS85964.1 - 0.92 7.9 16.0 1.2 7.5 16.0 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RUS85964.1 - 1.9 7.8 16.9 16 4.8 17.5 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CaM_binding PF07839.11 RUS85966.1 - 0.018 15.8 2.4 0.025 15.3 2.4 1.2 1 0 0 1 1 1 0 Plant calmodulin-binding domain Thymosin PF01290.20 RUS85967.1 - 1.7e-69 229.2 26.9 3.5e-11 42.6 0.3 7.1 7 0 0 7 7 7 7 Thymosin beta-4 family WH2 PF02205.20 RUS85967.1 - 3.5e-08 33.0 5.6 2 8.4 0.0 5.8 5 0 0 5 5 5 4 WH2 motif P22_AR_N PF10547.9 RUS85967.1 - 0.0038 17.5 1.4 19 5.6 0.2 3.8 4 0 0 4 4 4 1 P22_AR N-terminal domain DUF4890 PF16231.5 RUS85967.1 - 0.021 15.3 10.5 1.4 9.4 1.5 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4890) DicB PF05358.11 RUS85967.1 - 0.034 14.3 5.5 48 4.2 0.2 4.9 2 2 2 5 5 5 0 DicB protein DUF3926 PF13080.6 RUS85967.1 - 0.049 13.6 0.6 11 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) DUF2294 PF10057.9 RUS85967.1 - 0.1 12.7 11.0 6.9 6.9 0.1 4.6 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2294) Phage_Coat_B PF05356.11 RUS85968.1 - 0.004 17.0 0.1 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 Phage Coat protein B hemP PF10636.9 RUS85968.1 - 0.69 9.8 1.9 29 4.6 0.1 2.7 2 0 0 2 2 2 0 Hemin uptake protein hemP Ribosomal_L1 PF00687.21 RUS85969.1 - 3.5e-46 157.5 4.9 4.2e-46 157.3 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MaoC_dehydratas PF01575.19 RUS85969.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain WD40 PF00400.32 RUS85970.1 - 5.3e-27 93.5 9.7 9.7e-07 29.4 2.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS85970.1 - 2.2e-13 50.3 0.1 0.043 14.1 0.0 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS85970.1 - 0.00071 19.5 0.0 0.15 11.9 0.0 3.4 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 RUS85970.1 - 0.0056 15.8 0.0 0.12 11.4 0.0 2.6 2 1 0 3 3 3 1 Coatomer WD associated region Suf PF05843.14 RUS85970.1 - 1.7 8.6 5.5 2.7 7.9 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PID PF00640.23 RUS85971.1 - 1.9e-20 73.3 0.1 3.2e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 RUS85971.1 - 6.5e-12 45.1 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS85971.1 - 2.3e-08 33.5 0.0 1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain PTB PF08416.13 RUS85971.1 - 9.4e-06 25.8 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 RUS85971.1 - 0.00031 20.7 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 RUS85971.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain PBP1_TM PF14812.6 RUS85972.1 - 7.5 7.0 30.4 0.11 12.9 5.9 3.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_jaz PF12171.8 RUS85973.1 - 9.2e-10 38.6 3.5 1.4e-09 38.0 3.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS85973.1 - 0.0015 18.8 0.1 0.0017 18.6 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RUS85973.1 - 0.0075 16.6 0.9 0.013 15.9 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 RUS85973.1 - 0.009 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 RUS85973.1 - 0.075 13.9 0.3 0.19 12.7 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.12 RUS85973.1 - 0.11 12.8 0.3 0.11 12.8 0.3 1.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) RabGAP-TBC PF00566.18 RUS85975.1 - 6.6e-54 182.8 3.8 9.6e-54 182.3 3.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 7TM_GPCR_Srw PF10324.9 RUS85976.1 - 2.3e-15 56.7 27.2 1.7e-13 50.6 27.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS85976.1 - 1e-10 41.4 23.4 1.3e-10 41.1 23.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS85976.1 - 5.6e-05 22.9 24.7 5.6e-05 22.9 24.7 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS85976.1 - 2.2 7.6 29.2 6.1 6.1 29.2 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Rx_N PF18052.1 RUS85977.1 - 0.17 12.2 0.1 0.17 12.2 0.1 1.7 2 0 0 2 2 2 0 Rx N-terminal domain CsoS2_M PF12288.8 RUS85978.1 - 7.7e-05 22.3 1.2 0.0002 20.9 1.2 1.7 1 1 0 1 1 1 1 Carboxysome shell peptide mid-region HLH PF00010.26 RUS85979.1 - 4.3e-13 49.0 0.3 1.1e-12 47.7 0.2 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain ATP_bind_3 PF01171.20 RUS85980.1 - 6.4e-17 61.9 0.0 8.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 RUS85980.1 - 0.023 13.5 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.12 RUS85980.1 - 0.032 13.7 2.0 0.032 13.7 2.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zn-ribbon_14 PF16503.5 RUS85981.1 - 4.8e-16 58.0 1.2 7.9e-16 57.3 1.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon RecR PF02132.15 RUS85981.1 - 0.84 9.3 6.8 1.8 8.2 6.8 1.6 1 0 0 1 1 1 0 RecR protein DUF2256 PF10013.9 RUS85982.1 - 1.1e-09 38.2 21.0 6.1 7.1 0.1 7.3 7 0 0 7 7 7 7 Uncharacterized protein conserved in bacteria (DUF2256) PBS_linker_poly PF00427.21 RUS85982.1 - 5.9e-09 36.0 11.5 0.091 12.8 0.1 6.9 2 1 5 7 7 7 3 Phycobilisome Linker polypeptide Eno-Rase_FAD_bd PF07055.12 RUS85982.1 - 5.9e-05 23.4 0.9 59 4.2 0.0 6.0 2 2 5 7 7 7 0 Enoyl reductase FAD binding domain TEX12 PF15219.6 RUS85982.1 - 0.00064 20.0 0.2 4.3e+02 1.3 0.0 6.7 8 0 0 8 8 8 0 Testis-expressed 12 DUF3346 PF11826.8 RUS85982.1 - 0.0011 18.9 18.9 13 5.4 0.2 6.7 1 1 6 7 7 7 2 Protein of unknown function (DUF3346) NYD-SP28_assoc PF14775.6 RUS85982.1 - 0.0015 18.6 9.9 1.2e+02 2.8 0.0 7.4 8 0 0 8 8 8 0 Sperm tail C-terminal domain cwf21 PF08312.12 RUS85982.1 - 0.49 10.6 22.8 46 4.3 0.2 7.2 7 0 0 7 7 7 0 cwf21 domain Pollen_Ole_e_I PF01190.17 RUS85982.1 - 2.3 8.6 15.3 18 5.8 0.8 4.2 1 1 6 7 7 7 0 Pollen proteins Ole e I like NleF_casp_inhib PF16809.5 RUS85982.1 - 4 7.3 9.5 2.2 8.2 0.3 4.0 2 2 2 5 5 5 0 NleF caspase inhibitor Phage_holin_2_4 PF16082.5 RUS85983.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF1043 PF06295.12 RUS85983.1 - 0.12 12.4 1.1 1.7 8.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TraL PF07178.11 RUS85983.1 - 0.25 11.8 0.0 0.54 10.8 0.0 1.5 1 0 0 1 1 1 0 TraL protein PLAC8 PF04749.17 RUS85984.1 - 5.7e-12 46.5 14.1 9.1e-12 45.9 14.1 1.3 1 0 0 1 1 1 1 PLAC8 family FYDLN_acid PF09538.10 RUS85984.1 - 0.16 12.7 0.0 0.25 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TMEM174 PF15029.6 RUS85984.1 - 0.35 10.5 3.2 0.53 10.0 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 AIG1 PF04548.16 RUS85985.1 - 2.1e-42 144.8 0.2 3.1e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 RUS85985.1 - 8.5e-06 25.8 0.2 2.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS85985.1 - 0.09 12.7 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 RUS85985.1 - 0.13 11.7 0.4 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B FNIP_N PF14636.6 RUS85985.1 - 0.16 12.9 0.4 0.3 12.1 0.4 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF87 PF01935.17 RUS85985.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain RNA_pol_3_Rpc31 PF11705.8 RUS85986.1 - 2.4e-06 28.0 44.4 0.0065 16.7 16.5 2.5 2 0 0 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RUS85986.1 - 0.0024 17.3 22.4 0.0024 17.3 22.4 2.3 2 0 0 2 2 2 1 NOA36 protein Serinc PF03348.15 RUS85986.1 - 0.0068 15.4 0.1 0.24 10.3 0.0 2.1 2 0 0 2 2 2 1 Serine incorporator (Serinc) PPP4R2 PF09184.11 RUS85986.1 - 0.007 16.0 7.1 0.007 16.0 7.1 2.2 2 0 0 2 2 2 1 PPP4R2 Nop14 PF04147.12 RUS85986.1 - 0.015 13.6 45.3 0.0096 14.2 16.0 2.1 2 0 0 2 2 2 0 Nop14-like family TFIIA PF03153.13 RUS85986.1 - 0.021 14.8 45.4 0.19 11.7 13.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RUS85986.1 - 0.12 10.5 79.9 0.28 9.2 35.2 2.1 2 0 0 2 2 2 0 DNA polymerase phi DUF913 PF06025.12 RUS85986.1 - 0.5 9.3 3.3 2 7.3 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 RUS85986.1 - 0.67 10.3 12.7 0.3 11.4 0.4 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 RUS85986.1 - 1.7 7.9 42.4 0.041 13.2 13.0 2.5 3 0 0 3 3 3 0 BUD22 SAPS PF04499.15 RUS85986.1 - 6.2 5.5 12.5 3.4 6.4 3.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein L51_S25_CI-B8 PF05047.16 RUS85987.1 - 0.53 10.2 6.5 1.2 9.1 2.1 2.8 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Extensin_2 PF04554.13 RUS85987.1 - 0.54 10.4 45.3 0.59 10.3 19.1 2.7 1 1 1 2 2 2 0 Extensin-like region DNA_pol_phi PF04931.13 RUS85988.1 - 2.5 6.1 4.6 3.3 5.7 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS85988.1 - 3 6.0 7.3 3.8 5.7 7.3 1.3 1 1 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS85988.1 - 8.2 5.6 7.5 15 4.8 7.5 1.4 1 0 0 1 1 1 0 NOA36 protein Jagunal PF07086.12 RUS85990.1 - 1.5e-59 201.2 0.4 1.7e-59 201.1 0.4 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF4131 PF13567.6 RUS85990.1 - 9.5 5.8 8.4 0.62 9.7 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RT_RNaseH PF17917.1 RUS85991.1 - 1.5e-62 208.4 0.0 5.7e-33 113.3 0.0 2.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS85991.1 - 2.5e-51 171.9 0.1 5.9e-27 93.6 0.0 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase LPP20 PF02169.16 RUS85991.1 - 0.18 12.1 0.8 12 6.3 0.1 2.3 2 0 0 2 2 2 0 LPP20 lipoprotein DUF3283 PF11686.8 RUS85991.1 - 0.23 11.3 1.9 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) BAF250_C PF12031.8 RUS85992.1 - 4.8e-99 330.8 0.6 7.8e-99 330.1 0.6 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 RUS85992.1 - 1.4e-17 64.1 0.0 3.1e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RRM_1 PF00076.22 RUS85993.1 - 1.3e-34 117.8 0.0 1.4e-08 34.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 RUS85993.1 - 0.096 12.9 0.0 6.4 7.1 0.0 3.4 4 0 0 4 4 4 0 BRCA1-associated protein 2 RRM_Rrp7 PF17799.1 RUS85993.1 - 0.23 11.3 0.0 36 4.1 0.0 3.0 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain SinI PF08671.10 RUS85993.1 - 6.4 6.7 8.9 15 5.5 0.3 4.0 4 0 0 4 4 4 0 Anti-repressor SinI GatB_N PF02934.15 RUS85994.1 - 1.3e-100 336.3 0.0 2e-100 335.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 RUS85994.1 - 5.6e-27 94.4 1.0 8.5e-27 93.9 1.0 1.3 1 0 0 1 1 1 1 GatB domain Homeodomain PF00046.29 RUS85997.1 - 1.6e-18 66.3 6.7 2.5e-18 65.7 6.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS85997.1 - 0.056 13.4 1.2 0.12 12.3 1.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF1397 PF07165.11 RUS85998.1 - 0.00027 20.4 4.3 0.00039 19.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1397) Spectrin PF00435.21 RUS85999.1 - 0 1385.6 248.5 5e-28 97.7 6.1 21.9 21 1 0 21 21 21 21 Spectrin repeat EFhand_Ca_insen PF08726.10 RUS85999.1 - 7.4e-25 86.8 4.4 2e-24 85.4 0.3 3.5 3 0 0 3 3 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 RUS85999.1 - 2.4e-14 51.7 1.3 1.5e-07 30.5 0.3 3.5 2 0 0 2 2 2 2 EF hand SH3_1 PF00018.28 RUS85999.1 - 2.9e-14 52.4 0.0 7.3e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS85999.1 - 3.6e-11 42.8 0.0 1.1e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 RUS85999.1 - 5.1e-10 39.7 5.9 7.1e-10 39.2 0.4 4.5 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS85999.1 - 1.1e-09 37.5 1.8 7.1e-06 25.5 0.3 4.4 4 0 0 4 4 3 2 EF-hand domain EF-hand_5 PF13202.6 RUS85999.1 - 3.8e-08 32.5 0.1 0.0021 17.5 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RUS85999.1 - 1.6e-07 31.1 1.2 0.0048 16.7 0.3 3.2 1 1 1 2 2 2 2 EF-hand domain pair SH3_2 PF07653.17 RUS85999.1 - 3.1e-07 30.0 0.0 7.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 RUS85999.1 - 0.036 14.1 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 SH3 domain Get5_bdg PF16843.5 RUS85999.1 - 0.084 12.4 0.0 2 7.9 0.0 3.5 4 0 0 4 4 4 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein zf-MIZ PF02891.20 RUS85999.1 - 0.17 11.7 4.5 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PPP5 PF08321.12 RUS85999.1 - 1.2 9.5 6.8 0.55 10.6 0.1 3.6 3 0 0 3 3 3 0 PPP5 TPR repeat region EF-hand_10 PF14788.6 RUS85999.1 - 1.8 8.5 5.5 0.66 9.9 0.4 3.0 3 0 0 3 3 3 0 EF hand DUF3287 PF11690.8 RUS85999.1 - 6.2 6.6 7.4 4.5 7.0 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) Somatomedin_B PF01033.17 RUS86000.1 - 1.6e-06 28.4 17.1 4.3e-06 27.0 17.1 1.7 1 0 0 1 1 1 1 Somatomedin B domain Peptidase_S28 PF05577.12 RUS86001.1 - 2.8e-139 464.6 5.8 3.2e-139 464.5 5.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 RUS86001.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS86001.1 - 0.038 13.2 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 fn3 PF00041.21 RUS86002.1 - 6.5e-10 39.2 0.9 4.5e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS86002.1 - 0.0022 18.5 1.1 0.0048 17.4 0.3 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 RUS86003.1 - 3.1e-11 43.5 0.1 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain WAP PF00095.21 RUS86003.1 - 3.6e-07 30.4 16.3 3.6e-07 30.4 16.3 3.3 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' UNC-93 PF05978.16 RUS86004.1 - 1.3e-10 41.2 6.3 1.3e-10 41.2 6.3 3.3 2 2 1 3 3 3 2 Ion channel regulatory protein UNC-93 MFS_2 PF13347.6 RUS86004.1 - 0.00027 19.6 4.7 0.00027 19.6 4.7 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RUS86004.1 - 0.0022 17.0 30.0 0.0072 15.3 8.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily UbiA PF01040.18 RUS86006.1 - 1.1e-48 165.8 16.7 1.3e-48 165.5 16.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mannosyl_trans4 PF15971.5 RUS86006.1 - 0.019 14.8 0.5 0.052 13.4 0.1 1.9 1 1 0 1 1 1 0 DolP-mannose mannosyltransferase Ost4 PF10215.9 RUS86006.1 - 0.067 13.0 4.1 0.32 10.8 0.3 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase L_HMGIC_fpl PF10242.9 RUS86007.1 - 3.5e-27 95.8 0.4 4.1e-14 53.2 0.1 2.0 2 0 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein DUF4014 PF13198.6 RUS86007.1 - 0.00015 22.1 0.4 0.82 10.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4014) DUF2208 PF09973.9 RUS86007.1 - 0.00029 20.5 0.8 0.4 10.3 0.1 2.0 1 1 1 2 2 2 2 Predicted membrane protein (DUF2208) TMEM107 PF14995.6 RUS86007.1 - 0.00048 20.6 0.9 0.66 10.4 0.1 2.1 2 0 0 2 2 2 2 Transmembrane protein Cytochrom_B_N_2 PF13631.6 RUS86007.1 - 0.00063 19.8 0.6 0.54 10.2 0.1 2.2 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB DUF2963 PF11178.8 RUS86007.1 - 0.0015 18.2 0.5 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2963) Claudin_3 PF06653.11 RUS86007.1 - 0.0024 17.8 2.5 1.2 9.0 0.2 2.2 2 0 0 2 2 2 2 Tight junction protein, Claudin-like DUF3784 PF12650.7 RUS86007.1 - 0.0065 16.6 0.1 4.9 7.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3784) DUF2207 PF09972.9 RUS86007.1 - 0.016 14.0 0.2 0.023 13.5 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 RUS86007.1 - 0.016 15.1 4.2 2.7 8.0 0.3 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C CCDC-167 PF15188.6 RUS86007.1 - 0.022 15.1 0.1 7.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF485 PF04341.12 RUS86007.1 - 0.025 14.5 3.5 3.3 7.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Holin_BlyA PF05102.12 RUS86007.1 - 0.077 13.0 2.1 9.8 6.2 0.2 2.3 2 0 0 2 2 2 0 holin, BlyA family PDR_CDR PF06422.12 RUS86007.1 - 0.12 12.3 5.1 4.4 7.3 0.4 2.3 2 0 0 2 2 2 0 CDR ABC transporter Synaptobrevin PF00957.21 RUS86007.1 - 0.12 12.2 6.2 2.9 7.8 0.5 2.1 2 0 0 2 2 2 0 Synaptobrevin CoA_binding_3 PF13727.6 RUS86007.1 - 0.13 12.3 3.2 5.9 6.9 0.2 2.2 2 0 0 2 2 2 0 CoA-binding domain FAM209 PF15206.6 RUS86007.1 - 0.14 12.0 0.5 10 5.9 0.1 2.1 1 1 1 2 2 2 0 FAM209 family DUF4890 PF16231.5 RUS86007.1 - 0.14 12.7 0.6 12 6.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) GRP PF07172.11 RUS86007.1 - 0.21 12.3 0.1 35 5.2 0.0 2.3 2 0 0 2 2 2 0 Glycine rich protein family SecD-TM1 PF13721.6 RUS86007.1 - 0.22 12.0 2.7 13 6.3 0.1 2.4 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DUF2417 PF10329.9 RUS86007.1 - 0.35 10.2 12.8 1.6 8.1 2.6 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) DUF2116 PF09889.9 RUS86007.1 - 0.57 10.2 2.3 26 4.9 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Lig_chan PF00060.26 RUS86007.1 - 0.83 9.5 6.1 8.9 6.1 0.6 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel ITI_HC_C PF06668.12 RUS86008.1 - 1.3e-09 38.0 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus HTH_30 PF13556.6 RUS86008.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain L_HMGIC_fpl PF10242.9 RUS86009.1 - 3.1e-53 180.7 12.9 3.7e-53 180.4 12.9 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 RUS86009.1 - 6.6e-06 26.1 9.0 8.4e-06 25.8 8.6 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Atthog PF18800.1 RUS86009.1 - 2.3e-05 24.3 3.0 4e-05 23.6 3.0 1.4 1 0 0 1 1 1 1 Attenuator of Hedgehog MARVEL PF01284.23 RUS86009.1 - 0.00014 21.9 14.0 0.00049 20.1 13.9 1.9 1 1 0 1 1 1 1 Membrane-associating domain Claudin_2 PF13903.6 RUS86009.1 - 0.077 12.7 14.7 0.49 10.1 15.1 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2569 PF10754.9 RUS86009.1 - 0.17 12.4 6.5 0.064 13.7 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Orai-1 PF07856.12 RUS86009.1 - 1.6 8.4 8.9 3.2 7.4 8.7 1.6 1 1 0 1 1 1 0 Mediator of CRAC channel activity BAR_3 PF16746.5 RUS86010.1 - 7.8e-46 156.7 15.6 1.4e-45 155.9 15.6 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PID PF00640.23 RUS86010.1 - 6.3e-17 61.9 0.0 2.3e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS86010.1 - 0.00056 20.1 0.1 0.0029 17.8 0.1 2.2 1 1 0 1 1 1 1 Phosphotyrosine-binding domain Caskin-tail PF16632.5 RUS86010.1 - 0.0026 18.1 0.5 0.01 16.2 0.5 2.1 1 0 0 1 1 1 1 C-terminal region of Caskin PH PF00169.29 RUS86010.1 - 0.014 15.9 0.1 0.079 13.5 0.0 2.3 3 0 0 3 3 3 0 PH domain LIF_OSM PF01291.17 RUS86010.1 - 0.035 14.2 1.0 0.075 13.2 1.0 1.5 1 0 0 1 1 1 0 LIF / OSM family RecG_N PF17190.4 RUS86010.1 - 0.1 13.3 5.1 14 6.5 0.1 3.4 3 0 0 3 3 3 0 RecG N-terminal helical domain DUF5547 PF17701.1 RUS86010.1 - 0.3 11.0 2.9 13 5.7 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5547) DUF599 PF04654.12 RUS86011.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 ubiquitin PF00240.23 RUS86012.1 - 2.7e-06 27.0 0.0 7.9e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS86012.1 - 0.0024 17.7 0.0 0.0073 16.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IQ PF00612.27 RUS86012.1 - 0.01 15.5 1.8 0.022 14.5 1.8 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif ISN1 PF06437.11 RUS86014.1 - 0.033 13.1 0.0 0.052 12.4 0.0 1.3 1 1 0 1 1 1 0 IMP-specific 5'-nucleotidase RNA12 PF10443.9 RUS86015.1 - 0.0066 15.2 0.3 0.01 14.6 0.3 1.2 1 0 0 1 1 1 1 RNA12 protein USP8_interact PF08941.10 RUS86015.1 - 0.037 13.8 0.3 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 USP8 interacting PIN_6 PF17146.4 RUS86015.1 - 0.1 13.1 0.1 32 5.1 0.0 2.8 3 0 0 3 3 3 0 PIN domain of ribonuclease DUF2730 PF10805.8 RUS86015.1 - 0.11 12.5 5.1 2 8.5 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3877 PF12993.7 RUS86015.1 - 0.12 12.2 2.3 0.15 11.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) NleF_casp_inhib PF16809.5 RUS86015.1 - 0.24 11.3 1.7 4 7.3 0.0 2.9 4 0 0 4 4 4 0 NleF caspase inhibitor PHM7_cyt PF14703.6 RUS86015.1 - 0.78 10.0 4.4 0.44 10.8 0.3 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Latarcin PF10279.9 RUS86015.1 - 1.9 9.0 7.5 55 4.3 4.5 3.0 2 1 0 2 2 2 0 Latarcin precursor SCAB_CC PF16712.5 RUS86016.1 - 0.017 15.0 1.0 0.025 14.4 1.0 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein 7tm_1 PF00001.21 RUS86017.1 - 3.9e-39 134.5 6.8 8.7e-34 117.0 3.0 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS86017.1 - 0.0029 17.3 0.2 0.0029 17.3 0.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS86017.1 - 0.0056 16.1 4.9 1.8 7.9 0.2 3.1 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS86017.1 - 0.096 12.0 1.7 0.082 12.2 0.2 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 RUS86017.1 - 0.33 10.6 15.2 0.27 10.9 1.0 3.7 4 0 0 4 4 4 0 Olfactory receptor Glyco_transf_90 PF05686.12 RUS86018.1 - 8.7e-104 347.6 4.2 1e-103 347.3 4.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 RUS86018.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFIID-18kDa PF02269.16 RUS86019.1 - 4.6e-26 90.7 0.2 1e-25 89.6 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF188 PF02639.14 RUS86019.1 - 0.00063 19.4 0.5 0.0013 18.4 0.3 1.6 1 1 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 Dynein_heavy PF03028.15 RUS86019.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain LRR_8 PF13855.6 RUS86020.1 - 7.1e-42 141.0 31.0 7.5e-17 60.8 0.6 8.2 3 2 5 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 RUS86020.1 - 1.7e-19 69.5 41.0 2e-05 24.8 0.1 11.6 10 2 4 15 15 15 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS86020.1 - 1.7e-08 34.5 0.0 0.00069 19.6 0.0 4.0 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS86020.1 - 1.5e-07 31.0 9.1 1.2e-05 24.9 0.2 4.4 1 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 RUS86020.1 - 1.7e-07 30.8 26.5 4.8 8.1 0.0 11.7 12 2 1 13 13 13 4 Leucine Rich Repeat LRR_6 PF13516.6 RUS86020.1 - 5.3e-06 26.1 18.6 0.32 11.2 0.3 9.3 9 0 0 9 9 9 2 Leucine Rich repeat MLANA PF14991.6 RUS86020.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Syndecan PF01034.20 RUS86020.1 - 0.23 11.4 0.1 0.44 10.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Acetyltransf_1 PF00583.25 RUS86021.1 - 2.6e-15 56.7 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RUS86021.1 - 2.9e-09 36.9 0.1 3.7e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RUS86021.1 - 3.3e-08 33.8 0.0 5.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS86021.1 - 1.7e-07 31.1 0.0 2.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RUS86021.1 - 0.00017 21.6 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 RUS86021.1 - 0.0033 17.4 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 RUS86021.1 - 0.0034 16.9 0.6 0.0076 15.7 0.5 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 RUS86021.1 - 0.015 16.0 0.0 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 RUS86021.1 - 0.056 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Pkinase PF00069.25 RUS86023.1 - 2.5e-37 128.7 0.0 1e-36 126.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86023.1 - 6.7e-13 48.5 0.0 3e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ThiC-associated PF13667.6 RUS86024.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain DASH_Dam1 PF08653.10 RUS86025.1 - 0.49 10.2 0.1 0.49 10.2 0.1 2.7 3 1 2 5 5 5 0 DASH complex subunit Dam1 Cys_rich_VLP PF14194.6 RUS86025.1 - 3.8 7.7 6.4 9.2 6.5 1.6 2.6 2 1 1 3 3 3 0 Cysteine-rich VLP Zn-C2H2_12 PF18112.1 RUS86025.1 - 7.3 7.1 26.2 6.5 7.3 0.7 6.7 3 2 4 7 7 7 0 Autophagy receptor zinc finger-C2H2 domain Cuticle_2 PF08184.11 RUS86026.1 - 0.0016 18.4 0.5 37 4.4 0.1 3.9 2 1 2 4 4 4 3 Cuticle protein 7 isoform family Sigma70_r1_2 PF00140.20 RUS86026.1 - 0.056 13.5 11.0 47 4.1 0.1 5.7 6 0 0 6 6 6 0 Sigma-70 factor, region 1.2 Antimicrobial25 PF16839.5 RUS86027.1 - 0.28 11.3 5.0 6.1 7.0 0.8 2.3 2 0 0 2 2 2 0 Nematode antimicrobial peptide VirDNA-topo-I_N PF09266.10 RUS86028.1 - 0.05 13.8 13.6 5 7.4 0.3 4.2 1 1 3 4 4 4 0 Viral DNA topoisomerase I, N-terminal Exo_endo_phos_2 PF14529.6 RUS86031.1 - 1.8e-17 63.2 0.0 3.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS86031.1 - 6e-07 29.2 0.3 8.2e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5572 PF17733.1 RUS86031.1 - 0.02 14.7 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5572) Ammonium_transp PF00909.21 RUS86032.1 - 8.5e-72 242.0 19.1 1.3e-71 241.4 19.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_trans_4_4 PF13579.6 RUS86032.1 - 0.14 12.6 0.2 0.28 11.6 0.2 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Lectin_C PF00059.21 RUS86033.1 - 1.5e-05 25.7 1.2 1.9e-05 25.3 0.3 1.6 2 0 0 2 2 2 1 Lectin C-type domain Miga PF10265.9 RUS86034.1 - 0.003 16.6 0.0 0.0038 16.3 0.0 1.1 1 0 0 1 1 1 1 Mitoguardin Protocadherin PF08374.11 RUS86034.1 - 0.035 14.1 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Ferric_reduct PF01794.19 RUS86034.1 - 0.091 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component EphA2_TM PF14575.6 RUS86034.1 - 0.11 13.4 0.1 0.27 12.2 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Metal_resist PF13801.6 RUS86034.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Lectin_C PF00059.21 RUS86035.1 - 9.1e-24 84.3 8.4 4.9e-12 46.5 3.5 2.1 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 RUS86036.1 - 2.8e-14 53.8 0.5 1e-13 52.0 0.5 2.1 1 0 0 1 1 1 1 Lectin C-type domain Nop14 PF04147.12 RUS86037.1 - 0.046 12.0 34.8 0.057 11.6 34.8 1.1 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 RUS86037.1 - 0.12 12.2 2.3 0.13 12.1 2.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 RUS86037.1 - 0.77 8.0 28.0 1.1 7.4 28.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS86037.1 - 2.4 6.5 27.3 3.8 5.8 27.3 1.3 1 0 0 1 1 1 0 Mpp10 protein Lectin_C PF00059.21 RUS86038.1 - 6.2e-18 65.5 0.5 2.6e-17 63.5 0.5 2.2 1 0 0 1 1 1 1 Lectin C-type domain Laminin_EGF PF00053.24 RUS86038.1 - 0.22 11.7 132.3 0.083 13.0 21.6 7.6 1 1 6 7 7 7 0 Laminin EGF domain Lectin_C PF00059.21 RUS86039.1 - 1.4e-15 57.9 0.4 2.1e-15 57.4 0.4 1.2 1 0 0 1 1 1 1 Lectin C-type domain Laminin_EGF PF00053.24 RUS86040.1 - 3.3e-09 36.8 87.1 0.024 14.8 3.9 5.4 1 1 4 5 5 5 5 Laminin EGF domain Laminin_EGF PF00053.24 RUS86041.1 - 0.0016 18.6 73.9 0.52 10.5 20.3 5.4 1 1 4 5 5 5 3 Laminin EGF domain EGF_2 PF07974.13 RUS86041.1 - 0.024 15.0 14.3 0.024 15.0 14.3 8.2 7 1 1 8 8 8 0 EGF-like domain HSL_N PF06350.12 RUS86042.1 - 3.9e-103 344.6 0.1 5e-103 344.3 0.1 1.1 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 RUS86042.1 - 1.6e-47 162.1 0.3 1.8e-34 119.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RUS86042.1 - 2.3e-09 36.6 0.0 3.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 RUS86042.1 - 0.21 11.1 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) E1-E2_ATPase PF00122.20 RUS86043.1 - 6.4e-45 152.9 1.8 6.4e-45 152.9 1.8 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RUS86043.1 - 6e-43 146.7 0.2 6e-43 146.7 0.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RUS86043.1 - 1.4e-22 79.5 0.0 2.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RUS86043.1 - 8.1e-19 68.7 0.0 2.8e-09 37.6 0.0 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RUS86043.1 - 3.5e-14 52.2 0.0 7.1e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RUS86043.1 - 6.4e-06 26.1 1.1 0.00068 19.5 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RUS86043.1 - 0.21 11.9 0.3 1.3 9.4 0.2 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase MgtE PF01769.16 RUS86043.1 - 0.36 11.2 9.4 1.2 9.5 4.2 2.8 3 0 0 3 3 3 0 Divalent cation transporter NUDE_C PF04880.13 RUS86043.1 - 1.6 9.1 6.6 17 5.8 0.0 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region WD40 PF00400.32 RUS86044.1 - 1.7e-19 69.8 4.2 0.0015 19.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86044.1 - 0.016 15.5 0.1 2.4 8.5 0.0 3.7 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Innate_immun PF12782.7 RUS86046.1 - 0.0066 16.0 18.1 0.42 10.1 4.1 3.7 1 1 3 4 4 4 4 Invertebrate innate immunity transcript family DUF1970 PF09301.10 RUS86046.1 - 0.45 10.8 4.2 17 5.7 4.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) SDA1 PF05285.12 RUS86047.1 - 0.01 15.3 50.9 0.015 14.8 50.9 1.2 1 0 0 1 1 1 0 SDA1 FAD_binding_7 PF03441.14 RUS86048.1 - 2.5e-76 255.7 1.0 3.3e-76 255.3 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 RUS86048.1 - 5.6e-40 137.0 0.0 8.1e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Fibrinogen_C PF00147.18 RUS86049.1 - 4.1e-53 180.4 6.2 5.6e-53 180.0 6.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FucT_N PF18025.1 RUS86049.1 - 0.032 14.7 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain TetR_C_8 PF14278.6 RUS86049.1 - 0.082 13.0 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Homeodomain PF00046.29 RUS86050.1 - 1.3e-23 82.6 6.1 2.6e-23 81.6 6.1 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS86050.1 - 0.00034 20.3 2.9 0.00086 19.1 2.9 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 RUS86050.1 - 0.091 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain zf-C2H2 PF00096.26 RUS86052.1 - 5.5e-10 39.2 43.6 0.00016 22.0 0.6 6.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86052.1 - 1.8e-07 31.4 45.5 0.0018 19.0 0.8 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS86052.1 - 7e-06 26.2 18.8 0.01 16.1 0.6 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS86052.1 - 1.5e-05 25.2 8.0 0.00019 21.7 1.6 6.8 9 0 0 9 9 9 2 Zinc-finger double domain zf-met PF12874.7 RUS86052.1 - 1.6e-05 25.1 13.3 0.012 16.0 0.6 4.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS86052.1 - 0.75 10.1 18.7 1.2 9.4 0.6 3.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS86053.1 - 2.4e-07 30.9 5.2 1.4e-05 25.3 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS86053.1 - 3.8e-05 23.8 2.0 0.0012 19.0 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS86053.1 - 0.00021 21.6 1.6 0.15 12.4 0.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 RUS86053.1 - 0.051 13.8 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 RUS86053.1 - 0.055 13.6 0.7 5.9 7.1 0.1 2.5 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_9 PF16293.5 RUS86053.1 - 0.2 11.5 1.0 7 6.6 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Cytochrom_C PF00034.21 RUS86054.1 - 5.2e-13 49.9 0.0 6.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 RUS86054.1 - 1.1e-06 28.8 2.2 5.5e-06 26.6 2.2 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RUS86054.1 - 0.00013 21.7 2.2 0.00063 19.5 2.2 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 RUS86054.1 - 0.17 11.4 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Glyco_hydro_63 PF03200.16 RUS86055.1 - 1.3e-211 703.7 2.8 1.7e-211 703.3 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 RUS86055.1 - 1.2e-41 143.3 0.2 2.9e-41 142.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 RUS86055.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Utp14 PF04615.13 RUS86056.1 - 0.0084 14.7 70.9 0.01 14.5 70.9 1.1 1 0 0 1 1 1 1 Utp14 protein CDC27 PF09507.10 RUS86056.1 - 0.9 8.9 81.0 1.1 8.6 81.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.9 RUS86056.1 - 1.8 7.0 53.6 2 6.8 53.6 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 RUS86056.1 - 6.5 3.7 36.0 7.5 3.5 36.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAF PF01590.26 RUS86057.1 - 2.2e-17 63.9 0.0 5.8e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 RUS86057.1 - 7.1e-08 32.9 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RUS86057.1 - 0.12 12.7 0.0 0.55 10.6 0.0 2.1 2 1 0 2 2 2 0 GAF domain SPX PF03105.19 RUS86057.1 - 0.26 11.2 8.8 0.31 10.9 8.8 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 RUS86057.1 - 0.75 8.3 6.6 0.91 8.0 6.6 1.2 1 0 0 1 1 1 0 Macoilin family SpoIIIAH PF12685.7 RUS86058.1 - 0.024 14.5 1.9 0.022 14.6 1.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 RUS86058.1 - 0.82 7.8 41.1 1 7.5 41.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RUS86058.1 - 7.4 5.4 5.1 10 5.0 5.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) VWA_N PF08399.11 RUS86059.1 - 6.3e-32 110.6 0.1 8e-32 110.3 0.1 1.1 1 0 0 1 1 1 1 VWA N-terminal VWA PF00092.28 RUS86060.1 - 4.8e-15 56.2 0.1 7.6e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS86060.1 - 6.1e-14 52.6 0.1 1.2e-13 51.7 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS86060.1 - 6.6e-14 52.1 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 RUS86060.1 - 1.3e-12 48.1 0.2 4.6e-12 46.2 0.3 1.9 1 1 0 1 1 1 1 Cache domain dCache_2 PF08269.11 RUS86060.1 - 0.0039 16.4 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 Cache domain CHASE PF03924.13 RUS86060.1 - 0.03 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 CHASE domain Cache_3-Cache_2 PF17201.4 RUS86060.1 - 0.048 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain VGCC_alpha2 PF08473.11 RUS86061.1 - 5.5e-13 48.5 0.3 6.9e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd CAP PF00188.26 RUS86062.1 - 9.1e-24 84.7 0.5 9.1e-24 84.7 0.5 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Gal-bind_lectin PF00337.22 RUS86063.1 - 0.0049 16.4 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin PAN_3 PF08277.12 RUS86063.1 - 0.025 14.4 10.7 0.033 14.0 9.3 1.9 2 0 0 2 2 2 0 PAN-like domain NPR2 PF06218.11 RUS86064.1 - 1.8e-77 261.0 9.7 1.1e-59 202.3 13.6 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 RUS86064.1 - 0.0018 18.8 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking WD40 PF00400.32 RUS86065.1 - 3.1e-18 65.8 9.9 1.4e-05 25.7 0.0 7.9 7 1 1 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86065.1 - 5.2e-13 49.1 0.5 0.0042 17.4 0.0 5.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS86065.1 - 0.00011 21.6 5.4 0.33 10.2 0.1 4.0 3 1 1 4 4 4 2 WD40-like domain eIF2A PF08662.11 RUS86065.1 - 0.0002 21.3 0.3 0.14 12.0 0.0 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 RUS86065.1 - 0.00087 18.4 2.2 0.52 9.3 0.0 4.8 3 2 2 5 5 5 1 Coatomer WD associated region Clathrin PF00637.20 RUS86065.1 - 0.0061 16.4 3.9 20 5.0 0.1 4.5 3 1 2 5 5 5 1 Region in Clathrin and VPS Peptidase_S51 PF03575.17 RUS86065.1 - 0.057 13.1 0.4 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S51 TPR_7 PF13176.6 RUS86065.1 - 0.13 12.3 4.8 2 8.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS86065.1 - 0.21 11.8 0.1 0.21 11.8 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ras PF00071.22 RUS86066.1 - 2.1e-57 193.2 0.3 2.4e-57 193.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86066.1 - 3.2e-21 75.8 0.0 5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS86066.1 - 6.3e-09 35.5 0.1 7.1e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS86066.1 - 0.00015 21.4 0.2 0.00029 20.5 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS86066.1 - 0.00044 20.3 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS86066.1 - 0.0051 16.7 2.2 1.6 8.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RUS86066.1 - 0.044 12.9 0.1 3 6.9 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit MITF_TFEB_C_3_N PF15951.5 RUS86067.1 - 6.7e-22 78.8 12.6 6.7e-22 78.8 12.6 2.7 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus HLH PF00010.26 RUS86067.1 - 1.5e-15 56.9 0.3 1.5e-15 56.9 0.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Peptidase_S41 PF03572.18 RUS86067.1 - 0.024 14.2 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S41 Usp PF00582.26 RUS86070.1 - 0.00012 22.6 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family SelP_N PF04592.14 RUS86070.1 - 0.32 10.4 7.6 0.43 9.9 7.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BTB PF00651.31 RUS86071.1 - 6.1e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS86071.1 - 1e-11 44.8 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2 PF00096.26 RUS86072.1 - 5.2e-14 51.8 45.6 0.00016 22.0 1.8 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86072.1 - 9.3e-14 51.0 39.2 0.0044 17.7 0.9 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS86072.1 - 1.7e-08 34.5 22.2 0.0054 17.0 1.0 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding SET PF00856.28 RUS86072.1 - 1.8e-07 31.7 0.0 3.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-H2C2_2 PF13465.6 RUS86072.1 - 2.3e-06 27.8 39.2 0.015 15.7 0.3 7.0 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS86072.1 - 4.9e-06 26.4 30.4 0.06 13.4 1.0 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RUS86072.1 - 0.0026 18.1 25.1 0.59 10.6 0.9 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS86072.1 - 0.0077 16.6 26.2 0.11 12.8 2.0 4.7 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) DUF1835 PF08874.10 RUS86072.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) zf-C2HC_2 PF13913.6 RUS86072.1 - 0.31 11.0 26.4 0.33 10.9 2.1 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 RUS86072.1 - 0.38 10.4 19.6 0.48 10.1 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 RUS86072.1 - 0.44 10.9 24.7 0.33 11.3 6.9 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 RUS86072.1 - 1 10.2 17.9 2.9 8.7 3.6 3.5 1 1 1 3 3 3 0 zinc-ribbon family Zf_RING PF16744.5 RUS86072.1 - 1.1 9.4 17.0 5.5 7.2 0.0 4.9 3 2 2 5 5 5 0 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 RUS86072.1 - 2.1 8.6 20.9 1.9 8.6 4.4 3.9 3 1 1 4 4 4 0 Zinc ribbon domain HNH_5 PF14279.6 RUS86072.1 - 2.3 8.1 11.5 11 6.0 2.2 4.7 4 1 0 4 4 4 0 HNH endonuclease zf-BED PF02892.15 RUS86072.1 - 2.4 8.3 31.5 1.3 9.2 0.7 5.3 2 2 3 5 5 5 0 BED zinc finger zf-C2H2_9 PF16293.5 RUS86072.1 - 6.5 6.7 7.4 51 3.8 0.1 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF930 PF06059.12 RUS86074.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) Sugar_tr PF00083.24 RUS86076.1 - 4.7e-20 71.9 3.8 4.7e-20 71.9 3.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS86076.1 - 4.8e-10 38.9 13.9 6.2e-10 38.5 13.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily EBP PF05241.12 RUS86077.1 - 3.4e-48 163.4 7.6 4.1e-48 163.2 7.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein UPF0020 PF01170.18 RUS86078.1 - 9.2e-29 100.5 0.0 2.4e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 RUS86078.1 - 1.8e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_25 PF13649.6 RUS86078.1 - 0.0043 17.7 0.0 0.02 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS86078.1 - 0.0043 17.7 0.0 0.098 13.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 RUS86078.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa tRNA-synt_2b PF00587.25 RUS86079.1 - 2.3e-40 138.5 0.0 4.1e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 RUS86079.1 - 1.2e-19 70.5 15.6 3e-17 62.8 1.9 3.5 2 1 1 3 3 3 3 Seryl-tRNA synthetase N-terminal domain TMEM154 PF15102.6 RUS86080.1 - 0.0088 16.0 1.5 0.009 15.9 0.1 1.8 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 RUS86080.1 - 0.02 15.7 0.1 0.086 13.7 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 RUS86080.1 - 0.062 13.5 0.6 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Adeno_E3_CR2 PF02439.15 RUS86080.1 - 0.076 12.8 1.0 0.15 11.8 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ly49 PF08391.10 RUS86080.1 - 0.091 13.1 1.7 0.12 12.7 0.1 2.0 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Holin_BhlA PF10960.8 RUS86080.1 - 0.11 12.5 2.2 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 BhlA holin family Ninjurin PF04923.12 RUS86080.1 - 0.18 11.7 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Ninjurin OAD_gamma PF04277.13 RUS86080.1 - 0.21 12.2 0.5 0.51 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Orthoreo_P10 PF07204.11 RUS86080.1 - 0.23 11.4 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ac76 PF05814.11 RUS86080.1 - 0.87 9.6 3.3 0.86 9.7 0.1 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) CRA PF06589.11 RUS86080.1 - 6.5 6.9 10.7 26 5.0 9.4 2.0 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Orf78 PF06024.12 RUS86081.1 - 0.0005 20.3 0.1 0.0005 20.3 0.1 4.1 2 1 0 2 2 1 1 Orf78 (ac78) BUD22 PF09073.10 RUS86081.1 - 0.046 13.1 11.0 0.054 12.8 11.0 1.1 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 RUS86081.1 - 0.059 13.3 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 RUS86081.1 - 0.25 9.4 38.8 0.33 9.0 38.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Protocadherin PF08374.11 RUS86081.1 - 0.31 11.0 0.1 0.31 11.0 0.1 3.6 2 1 0 2 2 1 0 Protocadherin Nop14 PF04147.12 RUS86081.1 - 0.75 7.9 23.4 0.97 7.6 23.4 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 RUS86081.1 - 1.5 7.3 19.8 1.8 7.0 19.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3357 PF11837.8 RUS86081.1 - 1.6 9.3 0.0 1.6 9.3 0.0 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF3357) DUF4448 PF14610.6 RUS86081.1 - 3 7.6 0.0 3 7.6 0.0 3.4 2 1 0 2 2 1 0 Protein of unknown function (DUF4448) Wzy_C PF04932.15 RUS86081.1 - 4.8 6.8 0.0 4.8 6.8 0.0 3.1 1 1 1 2 2 1 0 O-Antigen ligase Rhabdo_ncap PF00945.18 RUS86081.1 - 7.2 5.4 12.3 9.7 4.9 12.3 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Mpp10 PF04006.12 RUS86081.1 - 7.2 4.9 19.5 9.6 4.5 19.5 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS86081.1 - 9.1 5.6 24.5 13 5.1 24.5 1.1 1 0 0 1 1 1 0 SDA1 COMM_domain PF07258.14 RUS86082.1 - 1.1e-17 63.9 0.1 2.3e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 COMM domain 2OG-FeII_Oxy_2 PF13532.6 RUS86083.1 - 8.5e-34 117.5 0.0 1.3e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NTP_transferase PF00483.23 RUS86084.1 - 2.7e-53 181.1 0.0 5.2e-53 180.2 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 RUS86084.1 - 3.2e-15 55.2 10.7 9.7e-09 34.6 3.0 2.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RUS86084.1 - 3.9e-10 40.3 0.0 5.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RUS86084.1 - 0.00092 18.9 5.9 0.0018 18.0 1.2 3.4 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 RUS86084.1 - 0.0052 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase DUF4954 PF16314.5 RUS86084.1 - 0.02 13.1 0.3 0.029 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 RUS86084.1 - 0.046 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GN3L_Grn1 PF08701.11 RUS86085.1 - 2.1e-20 72.6 24.0 2.1e-20 72.6 24.0 3.6 4 0 0 4 4 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 RUS86085.1 - 1.3e-15 57.5 0.2 2.4e-12 46.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS86085.1 - 1.4e-13 50.6 0.2 1.1e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS86085.1 - 2.3e-05 24.3 0.3 0.019 14.9 0.3 2.7 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 RUS86085.1 - 0.001 18.5 0.2 0.037 13.4 0.0 2.5 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 RUS86085.1 - 0.035 13.6 0.0 0.035 13.6 0.0 3.8 4 1 0 4 4 4 0 Elongation factor Tu GTP binding domain cobW PF02492.19 RUS86085.1 - 0.068 12.7 0.1 1.6 8.3 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RUS86085.1 - 0.11 11.4 0.0 0.11 11.4 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RUS86085.1 - 0.15 12.1 16.4 0.2 11.7 4.9 4.1 2 2 0 2 2 2 0 Dynamin family Med30 PF11315.8 RUS86085.1 - 0.32 11.2 10.9 0.96 9.6 10.9 1.8 1 0 0 1 1 1 0 Mediator complex subunit 30 AAA_16 PF13191.6 RUS86085.1 - 1.1 9.6 3.8 11 6.3 0.0 3.1 4 1 0 4 4 4 0 AAA ATPase domain tRNA-synt_1c PF00749.21 RUS86086.1 - 1.4e-107 359.3 0.0 2.3e-107 358.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 RUS86086.1 - 1.9e-50 171.1 0.4 3.3e-50 170.2 0.4 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 RUS86086.1 - 4.1e-49 166.8 0.0 9.9e-49 165.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 RUS86086.1 - 1.1e-26 93.6 0.7 2.5e-26 92.4 0.7 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GatB_Yqey PF02637.18 RUS86086.1 - 0.073 12.9 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 GatB domain DUF1073 PF06381.11 RUS86086.1 - 0.12 11.1 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) ABC2_membrane_3 PF12698.7 RUS86087.1 - 7.2e-34 117.4 19.4 9.9e-34 117.0 19.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 RUS86087.1 - 5.8e-24 85.2 0.0 9.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS86087.1 - 2.8e-10 40.5 0.0 2.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 RUS86087.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 RUS86087.1 - 0.033 13.6 0.0 0.7 9.3 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS86087.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS86087.1 - 0.21 11.3 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain HpcH_HpaI PF03328.14 RUS86088.1 - 1.6e-25 89.5 0.1 2.8e-25 88.8 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 RUS86088.1 - 7.6e-05 22.0 0.0 8.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold FAM47 PF14642.6 RUS86089.1 - 3.1e-12 46.6 54.7 0.16 11.5 1.8 7.3 1 1 5 7 7 7 7 FAM47 family FliW PF02623.15 RUS86089.1 - 0.018 15.0 33.6 26 4.7 0.7 8.0 1 1 8 9 9 9 0 FliW protein SET PF00856.28 RUS86090.1 - 0.0017 18.8 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 SET domain LOH1CR12 PF10158.9 RUS86092.1 - 3.4e-35 120.9 0.5 4.6e-35 120.5 0.5 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF4715 PF15835.5 RUS86092.1 - 0.011 15.8 0.6 0.017 15.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DUF1664 PF07889.12 RUS86092.1 - 0.015 15.3 1.0 0.022 14.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Flu_NS2 PF00601.19 RUS86092.1 - 0.04 14.2 0.2 0.23 11.8 0.1 2.0 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) zf-CCHC PF00098.23 RUS86093.1 - 7.3e-06 25.8 2.9 1.8e-05 24.6 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS86093.1 - 0.00021 21.0 1.2 0.00044 20.0 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS86093.1 - 0.012 15.6 1.3 0.053 13.5 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 RUS86093.1 - 0.025 14.3 2.2 0.056 13.2 2.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PNMA PF14893.6 RUS86093.1 - 0.033 13.6 0.0 0.43 9.9 0.0 2.0 1 1 1 2 2 2 0 PNMA Bacteriocin_II PF01721.18 RUS86095.1 - 0.14 12.3 0.2 0.45 10.7 0.2 1.9 1 0 0 1 1 1 0 Class II bacteriocin DUF1201 PF06716.11 RUS86096.1 - 0.00053 19.9 78.2 1.7 8.7 2.4 9.0 1 1 8 9 9 9 9 Protein of unknown function (DUF1201) Zein PF01559.16 RUS86096.1 - 0.0052 16.4 0.0 0.31 10.6 0.0 2.1 1 1 1 2 2 2 2 Zein seed storage protein DNA_binding_2 PF13724.6 RUS86096.1 - 0.014 15.8 11.8 3.7e+02 1.6 0.0 8.0 9 0 0 9 9 9 0 DNA-binding domain BmKX PF09132.10 RUS86097.1 - 0.0002 21.2 0.1 59 3.8 0.0 4.9 5 0 0 5 5 5 1 BmKX Defensin_RK-1 PF17860.1 RUS86097.1 - 0.035 14.6 0.0 1.6e+02 2.8 0.0 3.9 4 0 0 4 4 4 0 RK-1-like defensin Kindlin_2_N PF18124.1 RUS86097.1 - 0.28 11.4 1.4 37 4.6 0.1 2.6 1 1 3 4 4 4 0 Kindlin-2 N-terminal domain Lectin_N PF03954.14 RUS86098.1 - 0.0033 17.2 21.9 0.26 11.0 0.0 5.2 2 1 1 4 4 4 2 Hepatic lectin, N-terminal domain TSC22 PF01166.18 RUS86098.1 - 0.01 16.1 0.1 0.01 16.1 0.1 5.9 6 2 0 6 6 6 0 TSC-22/dip/bun family DUF4618 PF15397.6 RUS86098.1 - 0.069 12.6 0.3 0.069 12.6 0.3 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) NUDE_C PF04880.13 RUS86098.1 - 0.09 13.3 0.5 0.09 13.3 0.5 5.1 3 2 1 5 5 5 0 NUDE protein, C-terminal conserved region FapA PF03961.13 RUS86098.1 - 0.74 8.3 28.5 0.34 9.5 3.9 3.1 1 1 2 3 3 3 0 Flagellar Assembly Protein A GIT_CC PF16559.5 RUS86098.1 - 1.2 9.0 0.0 1.2 9.0 0.0 4.9 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 RUS86098.1 - 2.2 9.2 41.9 1.8 9.5 3.0 4.6 2 2 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF3410 PF11890.8 RUS86098.1 - 2.3 8.1 7.4 0.45 10.3 0.4 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3410) MAD PF05557.13 RUS86098.1 - 2.8 6.2 43.1 0.11 10.8 22.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4201 PF13870.6 RUS86098.1 - 3 7.6 41.4 1.4 8.6 11.0 4.8 1 1 2 4 4 4 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 RUS86098.1 - 3 7.1 21.8 0.039 13.3 11.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 RUS86098.1 - 3.9 7.5 47.1 0.26 11.3 4.2 5.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 RUS86099.1 - 0.012 15.6 8.6 0.012 15.6 8.6 3.1 1 1 2 3 3 3 0 Laminin Domain II Uso1_p115_C PF04871.13 RUS86099.1 - 0.025 14.9 15.6 0.025 14.9 15.6 3.8 1 1 2 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 RUS86099.1 - 0.031 14.3 8.6 0.62 10.1 2.8 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 RUS86099.1 - 0.41 10.3 50.0 0.76 9.4 9.7 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PspA_IM30 PF04012.12 RUS86099.1 - 0.54 9.8 40.0 0.5 9.9 3.6 4.0 1 1 0 2 2 2 0 PspA/IM30 family SlyX PF04102.12 RUS86099.1 - 0.72 10.5 31.8 0.61 10.7 3.2 5.4 3 1 2 5 5 5 0 SlyX IL2 PF00715.17 RUS86099.1 - 1.2 9.1 10.6 0.35 10.8 2.8 2.6 1 1 1 2 2 2 0 Interleukin 2 NPV_P10 PF05531.12 RUS86099.1 - 2.3 8.7 9.9 16 6.1 0.1 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF445 PF04286.12 RUS86099.1 - 2.4 7.9 26.6 3.1 7.5 26.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Golgin_A5 PF09787.9 RUS86099.1 - 3.6 7.0 43.5 0.17 11.3 18.9 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fez1 PF06818.15 RUS86099.1 - 4 7.8 44.5 0.36 11.3 28.5 2.6 1 1 2 3 3 3 0 Fez1 DUF641 PF04859.12 RUS86099.1 - 5.4 7.4 33.9 1.9 8.8 8.8 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.22 RUS86099.1 - 5.8 7.2 34.5 2.1 8.6 16.1 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 RUS86099.1 - 7.1 5.4 43.7 0.77 8.6 24.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CEP209_CC5 PF16574.5 RUS86100.1 - 2.2e-38 131.3 19.1 2.2e-38 131.3 19.1 11.0 9 2 0 9 9 9 1 Coiled-coil region of centrosome protein CE290 HAP1_N PF04849.13 RUS86100.1 - 7.2e-06 25.4 5.0 7.2e-06 25.4 5.0 10.4 4 3 5 10 10 10 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 RUS86100.1 - 0.0044 17.2 5.9 0.0044 17.2 5.9 13.3 7 3 4 13 13 13 3 Tropomyosin like RasGAP_C PF03836.15 RUS86100.1 - 0.011 15.8 0.9 0.011 15.8 0.9 10.8 7 4 6 13 13 13 0 RasGAP C-terminus Bcl-2 PF00452.19 RUS86100.1 - 0.8 10.4 4.1 1.2 9.9 0.2 3.5 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Apolipoprotein PF01442.18 RUS86101.1 - 5.4e-09 36.2 1.6 1.1e-07 31.9 1.6 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS86101.1 - 0.0045 17.0 20.5 36 4.4 20.5 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Colipase-like PF15083.6 RUS86101.1 - 0.0046 17.0 6.0 0.0081 16.3 6.0 1.4 1 0 0 1 1 1 1 Colipase-like tRNA_bind_2 PF13725.6 RUS86101.1 - 0.12 12.0 1.5 0.3 10.7 1.5 1.7 1 1 0 1 1 1 0 Possible tRNA binding domain DUF883 PF05957.13 RUS86101.1 - 0.15 12.7 9.9 1.9 9.1 2.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Nbl1_Borealin_N PF10444.9 RUS86101.1 - 0.41 10.3 4.4 37 4.0 0.2 3.7 1 1 3 4 4 4 0 Nbl1 / Borealin N terminal ATP-synt_B PF00430.18 RUS86101.1 - 0.96 9.5 8.1 4 7.5 7.3 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3672 PF12421.8 RUS86101.1 - 1.5 8.7 9.2 2.3 8.2 2.2 3.2 1 1 2 3 3 3 0 Fibronectin type III protein Nnf1 PF03980.14 RUS86101.1 - 2.5 8.5 11.5 3.4 8.1 2.1 3.1 1 1 2 3 3 3 0 Nnf1 REF PF05755.12 RUS86101.1 - 2.6 7.8 8.4 1.8 8.3 3.4 2.3 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) PIN_8 PF18476.1 RUS86101.1 - 7.9 6.3 11.2 68 3.2 11.2 2.1 1 1 0 1 1 1 0 PIN like domain CGI-121 PF08617.10 RUS86102.1 - 4.3e-05 23.7 4.7 2 8.5 0.1 3.3 1 1 2 3 3 3 3 Kinase binding protein CGI-121 RNA_pol_Rpb2_3 PF04565.16 RUS86102.1 - 5.5e-05 23.3 0.4 2.8 8.2 0.0 3.6 1 1 4 5 5 5 5 RNA polymerase Rpb2, domain 3 McyA_C PF12593.8 RUS86102.1 - 0.0013 18.5 27.1 4 7.3 0.2 6.7 1 1 6 7 7 7 6 Microcystin synthetase C terminal Phage_XkdX PF09693.10 RUS86102.1 - 0.0024 17.8 6.1 51 4.0 0.0 5.8 6 0 0 6 6 6 0 Phage uncharacterised protein (Phage_XkdX) DNA_Packaging_2 PF11123.8 RUS86102.1 - 0.0025 18.0 0.3 35 4.7 0.0 3.9 1 1 4 5 5 5 0 DNA packaging protein SoPB_HTH PF18090.1 RUS86102.1 - 0.0084 16.2 1.4 10 6.3 0.1 2.9 1 1 2 3 3 3 1 Centromere-binding protein HTH domain MecA PF05389.12 RUS86102.1 - 0.026 14.2 1.2 25 4.4 0.0 2.7 1 1 2 3 3 3 0 Negative regulator of genetic competence (MecA) Jacalin PF01419.17 RUS86102.1 - 0.08 12.9 3.1 29 4.6 0.1 2.8 1 1 2 3 3 3 0 Jacalin-like lectin domain DsrD PF08679.11 RUS86102.1 - 0.2 11.9 6.4 57 4.1 0.3 4.6 1 1 4 5 5 5 0 Dissimilatory sulfite reductase D (DsrD) Msg2_C PF12373.8 RUS86102.1 - 0.21 11.0 3.4 2.7e+02 1.1 0.0 5.1 6 0 0 6 6 6 0 Major surface glycoprotein 2 C terminal Inhibitor_I69 PF13734.6 RUS86102.1 - 1.6 9.2 5.5 1e+02 3.4 5.5 2.4 1 1 0 1 1 1 0 Spi protease inhibitor SNN_cytoplasm PF09051.10 RUS86102.1 - 7.9 6.4 22.7 1.1e+02 2.8 0.1 6.9 7 0 0 7 7 7 0 Stannin cytoplasmic DUF533 PF04391.12 RUS86103.1 - 9.8e-05 22.0 3.7 19 4.8 0.0 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF533) DUF4523 PF15023.6 RUS86103.1 - 0.002 18.0 0.5 15 5.3 0.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF4523) CNH PF00780.22 RUS86103.1 - 0.0024 17.5 7.4 7.2 6.1 0.1 4.5 1 1 1 4 4 4 1 CNH domain DUF4440 PF14534.6 RUS86103.1 - 0.0072 16.7 0.0 56 4.2 0.0 4.6 1 1 5 6 6 6 0 Domain of unknown function (DUF4440) Dicty_spore_N PF04562.12 RUS86103.1 - 0.012 16.3 3.8 4.5 8.0 0.4 3.3 1 1 2 3 3 3 0 Dictyostelium spore coat protein, N terminus Candida_ALS_N PF11766.8 RUS86103.1 - 0.013 14.8 9.8 16 4.7 0.0 4.7 1 1 5 6 6 6 0 Cell-wall agglutinin N-terminal ligand-sugar binding DUF4043 PF13252.6 RUS86103.1 - 0.029 13.5 0.7 93 2.0 0.0 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF4043) DUF3432 PF11914.8 RUS86103.1 - 0.042 14.1 2.9 8.5 6.7 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3432) S-AdoMet_synt_N PF00438.20 RUS86103.1 - 0.14 12.8 8.1 37 5.1 0.1 5.1 1 1 6 7 7 7 0 S-adenosylmethionine synthetase, N-terminal domain Cytochrom_CIII PF02085.16 RUS86103.1 - 0.24 11.8 7.6 13 6.2 0.6 3.3 1 1 1 2 2 2 0 Class III cytochrome C family TPR_3 PF07720.12 RUS86103.1 - 0.28 11.2 33.5 1.4e+02 2.6 0.0 10.7 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF3947 PF13135.6 RUS86103.1 - 1.9 8.7 8.8 75 3.6 0.2 4.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3947) MscS_porin PF12795.7 RUS86104.1 - 0.0013 18.4 11.3 0.0016 18.0 11.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain BST2 PF16716.5 RUS86104.1 - 0.0024 18.4 12.9 0.17 12.5 2.7 2.4 2 0 0 2 2 2 2 Bone marrow stromal antigen 2 HMMR_C PF15908.5 RUS86104.1 - 0.0041 17.4 0.7 0.0041 17.4 0.7 2.2 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal Pox_A_type_inc PF04508.12 RUS86104.1 - 0.0061 16.4 8.7 0.14 12.1 1.3 3.0 3 0 0 3 3 2 2 Viral A-type inclusion protein repeat Spc7 PF08317.11 RUS86104.1 - 0.0076 15.2 16.0 0.0092 14.9 16.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 RUS86104.1 - 0.0081 16.4 10.4 0.0081 16.4 10.4 2.1 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Leu_zip PF15294.6 RUS86104.1 - 0.009 15.6 14.2 0.012 15.2 14.2 1.1 1 0 0 1 1 1 1 Leucine zipper Dus PF01207.17 RUS86104.1 - 0.0093 15.1 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) JAKMIP_CC3 PF16034.5 RUS86104.1 - 0.013 15.5 15.3 0.035 14.1 15.3 1.8 1 1 0 1 1 1 0 JAKMIP CC3 domain WXG100 PF06013.12 RUS86104.1 - 0.025 14.8 4.6 0.5 10.6 4.4 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.7 RUS86104.1 - 0.03 14.5 22.9 0.1 12.7 22.9 1.8 1 1 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.12 RUS86104.1 - 0.03 14.4 19.9 0.39 10.8 6.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 RUS86104.1 - 0.03 14.7 3.3 0.03 14.7 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 RUS86104.1 - 0.041 13.2 10.0 0.054 12.8 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BshC PF10079.9 RUS86104.1 - 0.046 12.5 7.0 0.061 12.1 7.0 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC HrpB7 PF09486.10 RUS86104.1 - 0.047 14.1 10.0 0.76 10.2 0.7 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 RUS86104.1 - 0.054 13.9 14.5 0.092 13.2 14.4 1.4 1 1 0 1 1 1 0 Fez1 Spectrin PF00435.21 RUS86104.1 - 0.059 13.9 10.9 0.032 14.7 7.6 2.1 1 1 1 2 2 2 0 Spectrin repeat DLP_helical PF18709.1 RUS86104.1 - 0.065 12.4 12.8 0.17 11.1 2.4 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain APG6_N PF17675.1 RUS86104.1 - 0.069 13.7 18.3 0.18 12.3 3.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Cnn_1N PF07989.11 RUS86104.1 - 0.07 13.3 17.7 1 9.6 5.1 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 PilJ PF13675.6 RUS86104.1 - 0.076 13.0 1.9 0.14 12.2 1.8 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF730 PF05325.11 RUS86104.1 - 0.088 12.8 0.5 0.088 12.8 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Ssu72 PF04722.13 RUS86104.1 - 0.1 12.2 1.9 4.2 6.9 0.1 2.1 2 0 0 2 2 2 0 Ssu72-like protein Fzo_mitofusin PF04799.13 RUS86104.1 - 0.11 12.0 10.6 0.22 11.1 1.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 RUS86104.1 - 0.12 12.4 6.0 0.34 11.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 RUS86104.1 - 0.13 12.6 1.9 0.19 12.0 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Snapin_Pallidin PF14712.6 RUS86104.1 - 0.14 12.6 13.1 1.2 9.6 1.8 2.4 1 1 1 2 2 2 0 Snapin/Pallidin PspA_IM30 PF04012.12 RUS86104.1 - 0.15 11.6 17.3 1.1 8.8 6.5 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF948 PF06103.11 RUS86104.1 - 0.15 12.3 4.5 1.3 9.3 4.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 RUS86104.1 - 0.2 11.5 19.9 1.2 9.0 3.3 3.2 2 1 1 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.11 RUS86104.1 - 0.21 12.2 10.1 3 8.5 1.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 RUS86104.1 - 0.21 11.6 8.0 0.46 10.5 8.0 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF4472 PF14739.6 RUS86104.1 - 0.21 12.3 17.6 0.4 11.4 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) YscO PF07321.12 RUS86104.1 - 0.22 11.5 22.1 1.1 9.2 9.9 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO AAA_13 PF13166.6 RUS86104.1 - 0.22 10.1 18.4 3 6.4 18.4 2.0 1 1 0 1 1 1 0 AAA domain SOGA PF11365.8 RUS86104.1 - 0.24 12.5 13.7 0.83 10.8 4.2 2.2 2 0 0 2 2 2 0 Protein SOGA PHM7_cyt PF14703.6 RUS86104.1 - 0.3 11.3 13.5 39 4.4 13.5 2.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Swi5 PF07061.11 RUS86104.1 - 0.35 11.0 12.5 0.25 11.4 2.7 2.3 2 0 0 2 2 2 0 Swi5 EzrA PF06160.12 RUS86104.1 - 0.38 8.9 16.2 0.17 10.1 4.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA UPF0242 PF06785.11 RUS86104.1 - 0.4 10.8 14.6 0.56 10.3 14.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 RUS86104.1 - 0.43 10.1 4.6 0.49 9.9 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 RUS86104.1 - 0.53 9.3 12.4 0.63 9.1 12.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mod_r PF07200.13 RUS86104.1 - 0.55 10.3 18.5 0.23 11.6 5.2 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 RUS86104.1 - 0.6 10.4 10.2 3.4 8.0 1.9 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 RUS86104.1 - 0.61 10.6 19.8 0.32 11.5 7.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB KxDL PF10241.9 RUS86104.1 - 0.62 10.4 10.7 1.5 9.1 1.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein AAA_11 PF13086.6 RUS86104.1 - 0.76 9.5 5.6 0.86 9.3 5.6 1.2 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 RUS86104.1 - 1.1 7.8 11.1 1.5 7.3 11.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 RUS86104.1 - 1.2 9.1 19.8 0.49 10.3 12.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Macoilin PF09726.9 RUS86104.1 - 1.4 7.4 11.8 1.4 7.4 11.8 1.0 1 0 0 1 1 1 0 Macoilin family TMF_DNA_bd PF12329.8 RUS86104.1 - 1.4 9.0 24.5 0.73 9.9 8.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 RUS86104.1 - 1.4 9.0 16.3 0.4 10.8 4.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 RUS86104.1 - 1.6 9.5 10.9 5.9 7.6 1.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2207 PF09972.9 RUS86104.1 - 1.6 7.4 6.7 0.63 8.7 4.4 1.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Dzip-like_N PF13815.6 RUS86104.1 - 1.7 8.6 11.3 1.1 9.3 0.6 2.6 3 0 0 3 3 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FlaC_arch PF05377.11 RUS86104.1 - 1.8 9.0 15.9 4.1 7.9 1.7 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MctB PF11382.8 RUS86104.1 - 1.9 8.1 11.3 0.14 11.8 1.8 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB TMPIT PF07851.13 RUS86104.1 - 2.2 7.4 12.0 0.58 9.3 2.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein CENP-Q PF13094.6 RUS86104.1 - 2.3 8.4 21.0 1.1 9.5 7.5 2.3 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fungal_TACC PF12709.7 RUS86104.1 - 2.4 8.6 13.7 0.22 12.0 2.9 3.0 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Occludin_ELL PF07303.13 RUS86104.1 - 2.5 8.9 10.3 0.73 10.6 2.4 2.2 1 1 1 2 2 2 0 Occludin homology domain Prominin PF05478.11 RUS86104.1 - 2.6 5.9 7.1 5.5 4.8 7.1 1.5 1 1 0 1 1 1 0 Prominin zf-C4H2 PF10146.9 RUS86104.1 - 2.6 8.3 13.8 1.8 8.8 2.2 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein Med21 PF11221.8 RUS86104.1 - 3.1 8.0 17.9 3.1 8.0 5.2 2.6 2 1 0 2 2 2 0 Subunit 21 of Mediator complex ATP-synt_B PF00430.18 RUS86104.1 - 4.2 7.5 17.1 0.83 9.7 11.2 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4094 PF13334.6 RUS86104.1 - 4.7 7.7 9.6 4.2e+02 1.5 9.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 RUS86104.1 - 5.7 7.1 9.6 26 5.0 9.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 RUS86104.1 - 5.7 5.7 7.3 7.2 5.4 7.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PRKG1_interact PF15898.5 RUS86104.1 - 5.9 7.9 17.8 2.3e+02 2.8 15.8 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Med9 PF07544.13 RUS86104.1 - 6.1 7.0 11.6 1.3 9.2 5.8 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 RUS86104.1 - 6.3 7.5 15.8 0.63 10.7 4.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA CP12 PF02672.15 RUS86104.1 - 7.5 7.4 11.9 1.3 9.8 5.9 2.3 1 1 1 2 2 2 0 CP12 domain CENP-H PF05837.12 RUS86104.1 - 9.5 6.7 20.5 3.5 8.1 6.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Pyr_redox_2 PF07992.14 RUS86105.1 - 1.9e-32 112.7 1.2 2.8e-18 66.2 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 RUS86105.1 - 3.3e-06 26.9 0.0 9.8e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 RUS86105.1 - 0.0005 20.1 0.4 0.23 11.4 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 RUS86105.1 - 0.0079 16.7 4.4 1.6 9.3 0.9 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS86105.1 - 0.015 14.5 0.1 0.19 10.8 0.0 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 RUS86105.1 - 0.031 13.6 0.1 0.071 12.4 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 RUS86105.1 - 0.045 14.2 0.2 6.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 RUS86105.1 - 0.12 12.7 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS86105.1 - 0.25 10.9 3.2 3.2 7.2 2.9 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 RUS86105.1 - 0.4 9.7 6.3 0.56 9.2 0.1 2.5 2 1 1 3 3 3 0 Glucose inhibited division protein A Fzo_mitofusin PF04799.13 RUS86106.1 - 0.0015 18.1 6.7 0.24 10.9 0.6 3.9 1 1 3 4 4 4 4 fzo-like conserved region Hom_end PF05204.14 RUS86106.1 - 0.02 15.1 17.1 0.61 10.3 2.5 3.0 1 1 2 3 3 3 0 Homing endonuclease Armet PF10208.9 RUS86106.1 - 1.2 9.1 15.1 2.1 8.3 6.6 2.3 1 1 0 2 2 2 0 Degradation arginine-rich protein for mis-folding AGH PF17558.2 RUS86106.1 - 3.1 8.0 22.3 24 5.1 0.2 5.4 1 1 3 5 5 5 0 Androgenic gland hormone GST_N_3 PF13417.6 RUS86108.1 - 2.1e-16 60.1 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS86108.1 - 4.8e-12 46.0 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS86108.1 - 5.3e-11 42.7 0.0 9.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS86108.1 - 6.1e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS86108.1 - 0.0046 17.1 0.0 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF16 PF01519.16 RUS86108.1 - 0.0073 16.8 1.5 0.014 15.8 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 GST_C_3 PF14497.6 RUS86108.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Stevor PF17410.2 RUS86108.1 - 0.16 11.4 1.4 0.26 10.8 1.4 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4047 PF13256.6 RUS86108.1 - 0.36 11.0 2.5 0.28 11.4 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) TBCA PF02970.16 RUS86108.1 - 0.66 10.3 5.8 1.4 9.3 5.8 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Peptidase_M17 PF00883.21 RUS86109.1 - 4.9e-96 321.7 0.7 6.3e-96 321.3 0.7 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 RUS86109.1 - 2.9e-22 79.2 0.1 7.5e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 HMG_box PF00505.19 RUS86110.1 - 3.2e-16 59.5 0.4 3.2e-16 59.5 0.4 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS86110.1 - 2.3e-10 40.9 0.4 2.3e-10 40.9 0.4 2.7 2 1 0 2 2 2 1 HMG-box domain Radical_SAM_N PF08497.10 RUS86110.1 - 8.9 5.4 11.8 5.9 6.0 7.5 2.2 2 0 0 2 2 2 0 Radical SAM N-terminal Aminotran_1_2 PF00155.21 RUS86111.1 - 3.3e-94 316.1 0.0 3.8e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_17 PF18012.1 RUS86112.1 - 8.9e-24 83.0 0.1 1.9e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 RUS86112.1 - 6.2e-19 68.1 0.4 1.2e-18 67.2 0.4 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 RUS86112.1 - 3e-09 37.3 0.0 1.9e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 RUS86112.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS86112.1 - 0.0028 18.0 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GST_N_3 PF13417.6 RUS86113.1 - 9.7e-20 70.8 0.0 2.1e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS86113.1 - 8.4e-15 54.8 0.1 2.1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS86113.1 - 4.7e-12 46.1 0.0 9.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS86113.1 - 1.4e-07 31.4 0.1 3.3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS86113.1 - 2.3e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS86113.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RUS86113.1 - 0.0089 16.2 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin 7tm_1 PF00001.21 RUS86114.1 - 3.1e-24 85.7 6.5 5.9e-24 84.8 6.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86114.1 - 5.2e-14 52.3 13.3 8.4e-12 45.0 1.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS86114.1 - 2.3e-05 24.2 6.7 2.3e-05 24.2 6.7 3.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS86114.1 - 0.00073 19.0 2.0 0.00073 19.0 2.0 2.7 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srv FGFR3_TM PF18123.1 RUS86114.1 - 0.02 14.4 0.2 0.075 12.6 0.2 2.0 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain GST_C_3 PF14497.6 RUS86114.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HHH_4 PF14490.6 RUS86114.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain COesterase PF00135.28 RUS86115.1 - 2.8e-111 372.9 0.0 3.7e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS86115.1 - 3.3e-07 30.4 0.0 3.4e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS86115.1 - 0.18 11.3 0.1 0.38 10.2 0.1 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family BRO1 PF03097.18 RUS86116.1 - 9.2e-77 258.4 0.3 1.3e-76 258.0 0.3 1.2 1 0 0 1 1 1 1 BRO1-like domain PDZ PF00595.24 RUS86116.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS86116.1 - 8.7e-08 31.9 0.1 2.7e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 PDZ domain DUF5340 PF17275.2 RUS86116.1 - 0.11 12.6 0.9 4.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5340) Ntox24 PF15529.6 RUS86117.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 24 fn3 PF00041.21 RUS86117.1 - 0.034 14.5 0.3 0.072 13.4 0.3 1.5 1 0 0 1 1 1 0 Fibronectin type III domain SNF2_N PF00176.23 RUS86118.1 - 2.9e-67 226.9 5.5 1e-66 225.1 5.5 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RUS86118.1 - 1.3e-12 48.0 0.0 6.5e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS86118.1 - 4.7e-08 33.2 0.1 4.7e-08 33.2 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-GRF PF06839.12 RUS86118.1 - 0.001 19.1 4.0 0.001 19.1 4.0 2.3 2 0 0 2 2 2 1 GRF zinc finger Syntaxin-6_N PF09177.11 RUS86118.1 - 0.0097 16.4 1.3 0.13 12.8 0.1 3.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Ank_2 PF12796.7 RUS86119.1 - 1.7e-11 44.5 0.1 0.034 14.7 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86119.1 - 1.4e-08 35.1 0.3 0.6 10.8 0.0 6.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS86119.1 - 4.4e-08 33.2 1.6 0.084 13.2 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS86119.1 - 1.7e-06 28.2 0.0 4.8 7.8 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RUS86119.1 - 2.6e-06 27.3 3.0 0.28 11.9 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat ADH_N PF08240.12 RUS86120.1 - 2.2e-31 108.0 0.5 5.9e-31 106.6 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS86120.1 - 3.7e-23 81.9 0.5 6.2e-23 81.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RUS86120.1 - 3.4e-14 52.9 1.4 1.2e-13 51.0 1.4 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RUS86120.1 - 1.2e-05 26.4 0.0 1.9e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RUS86120.1 - 0.0024 17.2 1.9 0.0044 16.3 1.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MaoC_dehydratas PF01575.19 RUS86121.1 - 1.7e-31 108.4 0.0 2.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain SCP2 PF02036.17 RUS86121.1 - 2.6e-18 66.3 0.0 4.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RUS86121.1 - 0.00014 22.1 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal adh_short PF00106.25 RUS86122.1 - 2e-39 135.1 3.8 2.1e-39 135.0 2.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase MaoC_dehydratas PF01575.19 RUS86122.1 - 1.6e-34 118.1 0.1 6.8e-34 116.1 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain adh_short_C2 PF13561.6 RUS86122.1 - 6.3e-32 111.0 1.2 6.3e-32 111.0 1.2 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 RUS86122.1 - 2.3e-21 76.2 0.3 9.1e-21 74.3 0.2 2.0 2 0 0 2 2 2 1 SCP-2 sterol transfer family KR PF08659.10 RUS86122.1 - 4.2e-13 49.6 0.4 1.1e-12 48.3 0.4 1.6 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 RUS86122.1 - 4e-09 36.7 0.0 4.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 RUS86122.1 - 0.00044 20.5 0.2 0.0015 18.8 0.2 1.9 1 1 1 2 2 2 1 Alkyl sulfatase C-terminal Pkinase_Tyr PF07714.17 RUS86123.1 - 7.4e-85 284.3 0.0 1.1e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS86123.1 - 6.4e-38 130.6 0.0 9.8e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RUS86123.1 - 2.3e-15 56.1 16.4 4.6e-09 35.9 3.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 RUS86123.1 - 8.1e-09 35.5 3.4 2e-06 27.8 1.1 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 RUS86123.1 - 0.0051 17.2 9.2 0.11 13.0 3.4 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 RUS86123.1 - 0.01 16.4 0.6 0.13 12.9 0.2 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Ig_2 PF13895.6 RUS86123.1 - 0.01 16.1 1.1 0.044 14.1 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain Beta_helix PF13229.6 RUS86123.1 - 0.11 12.4 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Right handed beta helix region Ribosomal_L13 PF00572.18 RUS86124.1 - 0.19 12.0 0.2 0.32 11.2 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L13 c-SKI_SMAD_bind PF08782.10 RUS86125.1 - 0.46 10.7 3.2 1.5 9.1 0.9 2.3 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Metallophos PF00149.28 RUS86126.1 - 0.045 14.2 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase FKBP_C PF00254.28 RUS86127.1 - 1.2e-29 102.4 1.0 3.2e-29 101.1 0.1 2.2 2 1 1 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 RUS86127.1 - 1.5e-22 80.1 0.1 1.5e-22 80.1 0.1 2.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 RUS86127.1 - 0.01 16.3 0.0 0.038 14.5 0.0 2.0 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain SOG2 PF10428.9 RUS86127.1 - 0.19 10.9 8.9 0.27 10.4 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIF_alpha PF05793.12 RUS86127.1 - 0.83 8.2 40.9 1.2 7.7 40.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.13 RUS86127.1 - 1.5 8.3 26.2 2.4 7.7 26.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.10 RUS86127.1 - 2.3 6.8 9.0 3.1 6.4 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop14 PF04147.12 RUS86127.1 - 4.8 5.3 30.3 7.4 4.6 30.3 1.3 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.6 RUS86127.1 - 7.8 6.4 10.2 1.3 8.9 3.5 2.5 1 1 2 3 3 3 0 Testis-expressed protein 19 THAP PF05485.12 RUS86130.1 - 1.2e-15 58.1 0.4 3e-15 56.9 0.4 1.7 1 0 0 1 1 1 1 THAP domain GAS PF13851.6 RUS86130.1 - 0.00037 19.9 5.9 0.00049 19.5 5.9 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG5 PF04106.12 RUS86130.1 - 0.072 12.7 0.4 2.3 7.7 0.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg5 TolA_bind_tri PF16331.5 RUS86130.1 - 0.1 12.7 0.5 0.17 12.0 0.5 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Insulin PF00049.18 RUS86130.1 - 0.16 13.0 1.6 14 6.8 0.0 2.6 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family LRR_4 PF12799.7 RUS86132.1 - 4.5e-14 52.3 16.0 1.4e-06 28.5 0.5 5.5 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS86132.1 - 4.9e-08 32.6 21.8 3.7e-07 29.8 3.0 4.5 2 2 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RUS86132.1 - 0.00037 20.0 0.4 0.0012 18.4 0.5 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 RUS86132.1 - 0.0017 18.2 15.6 0.22 11.7 0.0 6.4 6 1 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 RUS86132.1 - 0.016 15.7 17.1 0.6 10.9 0.1 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat Mito_fiss_reg PF05308.11 RUS86133.1 - 0.21 11.7 11.9 0.28 11.2 11.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CwsA PF10814.8 RUS86135.1 - 0.2 11.8 2.1 0.4 10.8 1.1 2.0 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA DUF3744 PF12558.8 RUS86135.1 - 1.2 10.0 5.3 3.9 8.3 0.2 3.0 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter Lectin_C PF00059.21 RUS86136.1 - 7e-13 49.3 0.5 1.2e-12 48.5 0.1 1.6 2 0 0 2 2 2 1 Lectin C-type domain Sporozoite_P67 PF05642.11 RUS86136.1 - 0.036 12.2 4.2 0.046 11.8 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NAD_binding_4 PF07993.12 RUS86138.1 - 2.1e-77 259.8 0.0 2.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 RUS86138.1 - 4.4e-32 110.2 1.6 4.4e-32 110.2 1.6 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 RUS86138.1 - 2.5e-06 27.1 0.0 2.7e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RUS86138.1 - 1.2e-05 24.7 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 RUS86138.1 - 0.00046 19.7 0.0 0.0013 18.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 RUS86138.1 - 0.038 13.0 0.2 0.21 10.5 0.1 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DERM PF14704.6 RUS86139.1 - 9e-46 156.1 7.1 1.1e-45 155.8 7.1 1.0 1 0 0 1 1 1 1 Dermatopontin Thioredoxin PF00085.20 RUS86140.1 - 1.4e-06 28.2 0.1 3.9e-06 26.8 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin Phosducin PF02114.16 RUS86140.1 - 1.1e-05 24.5 0.2 1.3e-05 24.3 0.2 1.0 1 0 0 1 1 1 1 Phosducin Bap31_Bap29_C PF18035.1 RUS86140.1 - 0.044 13.8 0.6 0.099 12.7 0.6 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain OST3_OST6 PF04756.13 RUS86140.1 - 0.078 12.3 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 RUS86140.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Filament PF00038.21 RUS86141.1 - 6.1e-26 91.7 47.9 1e-24 87.7 47.9 2.2 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 RUS86141.1 - 5.5e-13 49.2 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Spc7 PF08317.11 RUS86141.1 - 0.00091 18.2 10.7 0.00091 18.2 10.7 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein UPF0242 PF06785.11 RUS86141.1 - 0.029 14.5 33.1 0.04 14.0 18.1 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus LemA PF04011.12 RUS86141.1 - 0.47 10.3 12.9 0.057 13.3 6.3 2.8 2 1 1 3 3 3 0 LemA family GAS PF13851.6 RUS86141.1 - 1 8.7 34.5 0.035 13.5 3.8 3.2 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 RUS86141.1 - 4.1 7.5 31.0 0.62 10.1 0.7 5.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding UPF0160 PF03690.13 RUS86142.1 - 3.3e-140 467.2 0.0 3.8e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Spt20 PF12090.8 RUS86143.1 - 0.0062 16.2 17.2 0.0062 16.2 17.2 2.1 2 0 0 2 2 2 1 Spt20 family Androgen_recep PF02166.16 RUS86143.1 - 0.6 8.9 14.1 1.1 8.0 14.1 1.3 1 0 0 1 1 1 0 Androgen receptor Lectin_C PF00059.21 RUS86144.1 - 9.6e-14 52.0 0.1 2.7e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 Lectin C-type domain PAN_1 PF00024.26 RUS86144.1 - 0.014 15.4 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 PAN domain Sugar_tr PF00083.24 RUS86145.1 - 1e-103 347.6 13.6 1.2e-103 347.4 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS86145.1 - 2.2e-16 59.8 32.8 2.2e-16 59.8 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 RUS86145.1 - 6.7 6.7 11.2 0.92 9.4 4.7 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Neur_chan_LBD PF02931.23 RUS86146.1 - 1.1e-08 34.8 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain LRAT PF04970.13 RUS86147.1 - 7.9e-27 94.1 0.0 1.2e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.19 RUS86147.1 - 0.0096 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family SURF2 PF05477.11 RUS86148.1 - 4.9e-44 150.8 0.7 5.8e-44 150.6 0.7 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Vps54_N PF10475.9 RUS86148.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Ax_dynein_light PF10211.9 RUS86149.1 - 1.2e-07 31.8 3.2 1.2e-07 31.8 3.2 5.2 5 2 1 6 6 6 2 Axonemal dynein light chain RasGAP_C PF03836.15 RUS86149.1 - 0.26 11.4 0.0 0.26 11.4 0.0 4.5 4 2 0 4 4 4 0 RasGAP C-terminus SOGA PF11365.8 RUS86149.1 - 10 7.4 16.5 3.4 8.9 0.2 4.6 4 1 0 4 4 4 0 Protein SOGA RVT_1 PF00078.27 RUS86150.1 - 3.6e-18 65.9 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl_transf_3 PF01757.22 RUS86151.1 - 6.3e-16 58.4 28.4 1.1e-15 57.5 28.2 1.5 1 1 0 1 1 1 1 Acyltransferase family MutL_C PF08676.11 RUS86152.1 - 2.3e-09 37.2 0.5 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain MutL_C PF08676.11 RUS86153.1 - 3.1e-07 30.3 0.0 3.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Spc24 PF08286.11 RUS86154.1 - 4.5e-09 36.5 0.3 4.5e-09 36.5 0.3 1.9 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 RUS86154.1 - 0.005 17.2 1.9 0.0058 17.0 1.9 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein phiKZ_IP PF12699.7 RUS86154.1 - 0.0056 15.9 2.0 0.0063 15.7 2.0 1.1 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins Laminin_I PF06008.14 RUS86154.1 - 0.0077 16.0 5.2 0.01 15.5 5.2 1.1 1 0 0 1 1 1 1 Laminin Domain I DUF4349 PF14257.6 RUS86154.1 - 0.019 14.4 2.3 0.025 14.0 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) 2OG-FeII_Oxy_2 PF13532.6 RUS86154.1 - 0.03 14.5 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily COG2 PF06148.11 RUS86154.1 - 0.032 14.3 3.0 0.056 13.5 1.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 RUS86154.1 - 0.041 13.9 10.2 0.072 13.1 10.2 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 RUS86154.1 - 0.079 10.9 3.1 0.083 10.8 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 RUS86154.1 - 0.097 11.3 5.7 0.12 11.0 5.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 RUS86154.1 - 0.11 11.3 7.5 0.15 10.9 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Interferon PF00143.19 RUS86154.1 - 0.12 12.5 2.7 0.1 12.8 0.5 1.8 1 1 1 2 2 2 0 Interferon alpha/beta domain AKNA PF12443.8 RUS86154.1 - 0.12 13.0 4.9 0.2 12.3 4.0 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor APG6_N PF17675.1 RUS86154.1 - 0.12 12.8 9.5 0.2 12.2 9.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region RasGAP_C PF03836.15 RUS86154.1 - 0.23 11.6 7.8 0.052 13.7 3.7 1.8 1 1 1 2 2 2 0 RasGAP C-terminus DivIC PF04977.15 RUS86154.1 - 0.44 10.4 7.2 0.11 12.3 2.5 2.1 1 1 0 2 2 2 0 Septum formation initiator YlqD PF11068.8 RUS86154.1 - 0.68 10.3 8.4 0.35 11.2 2.9 1.8 1 1 1 2 2 2 0 YlqD protein Prominin PF05478.11 RUS86154.1 - 0.71 7.8 3.0 0.86 7.5 3.0 1.1 1 0 0 1 1 1 0 Prominin CAML PF14963.6 RUS86155.1 - 4e-13 50.1 9.3 2.3e-12 47.6 9.3 1.9 1 1 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand GET2 PF08690.10 RUS86155.1 - 0.0019 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 Peptidase_M14 PF00246.24 RUS86156.1 - 2.3e-71 241.0 0.0 3e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 RUS86156.1 - 4.1e-06 27.0 0.0 6.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2817 PF10994.8 RUS86156.1 - 0.037 13.4 0.2 0.058 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 RUS86156.1 - 0.07 12.2 0.0 0.22 10.5 0.0 1.9 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family ETRAMP PF09716.10 RUS86156.1 - 0.31 11.1 2.5 0.58 10.3 2.5 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HMG_box PF00505.19 RUS86157.1 - 3.6e-17 62.5 14.3 3.3e-11 43.4 2.7 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS86157.1 - 3.4e-13 50.0 13.9 3.9e-08 33.8 1.7 2.7 3 0 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 RUS86157.1 - 0.0024 18.1 3.8 0.13 12.4 0.5 2.5 2 0 0 2 2 2 2 Protamine and protamine like Sin3_corepress PF08295.12 RUS86157.1 - 0.0026 17.8 1.4 0.0067 16.5 1.4 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor DUF4473 PF14747.6 RUS86157.1 - 0.97 10.0 7.9 1.8 9.2 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) Endonuc_Holl PF10107.9 RUS86157.1 - 1.7 8.4 10.7 0.16 11.8 1.6 2.4 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF3456 PF11938.8 RUS86157.1 - 2.4 8.6 13.9 3.9 8.0 5.4 2.4 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP DUF2115 PF09888.9 RUS86157.1 - 7 7.2 9.7 0.83 10.2 1.9 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) MAD PF05557.13 RUS86158.1 - 2.9e-115 386.2 93.5 3.6e-115 385.8 93.5 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Gp_dh_N PF00044.24 RUS86158.1 - 5.9 7.3 5.8 44 4.5 1.0 3.1 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Lectin_C PF00059.21 RUS86160.1 - 1.2e-14 54.9 0.1 5.1e-14 52.9 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain Insulin PF00049.18 RUS86161.1 - 1.2e-11 45.4 2.0 3.4e-11 44.0 2.0 1.8 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 RUS86161.1 - 0.095 12.7 1.8 5 7.2 0.2 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type DERM PF14704.6 RUS86162.1 - 1.7e-18 67.6 0.2 2.4e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Dermatopontin MCD PF05292.11 RUS86163.1 - 4.9e-92 308.1 0.0 2.7e-57 194.3 0.0 2.4 2 0 0 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 RUS86163.1 - 1.4e-14 53.9 0.1 3.3e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain polyprenyl_synt PF00348.17 RUS86164.1 - 1.5e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase NADH_B2 PF14813.6 RUS86165.1 - 1e-20 73.3 0.5 1.2e-20 73.0 0.5 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 CUB PF00431.20 RUS86166.1 - 1.6e-37 128.2 1.6 7.7e-20 71.3 0.1 3.2 3 1 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 RUS86166.1 - 0.00011 22.3 1.1 0.00011 22.3 1.1 2.5 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A CUB_2 PF02408.20 RUS86166.1 - 0.00078 19.2 1.9 0.0043 16.8 0.1 2.6 2 1 0 2 2 2 1 CUB-like domain DNA_pol3_finger PF17657.1 RUS86166.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain Sugar_tr PF00083.24 RUS86167.1 - 1.1e-33 116.9 17.9 1.6e-33 116.3 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS86167.1 - 1.1e-21 77.2 37.5 6.8e-15 54.8 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.20 RUS86168.1 - 0.0012 18.7 0.4 0.0023 17.8 0.4 1.4 1 0 0 1 1 1 1 Syndecan domain Orf78 PF06024.12 RUS86168.1 - 0.019 15.3 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 RUS86168.1 - 0.065 13.1 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family MLANA PF14991.6 RUS86168.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Insulin_TMD PF17870.1 RUS86168.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Sigma_reg_N PF13800.6 RUS86168.1 - 0.87 9.9 3.3 2.1 8.7 0.4 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Cadherin PF00028.17 RUS86169.1 - 1.2e-28 99.4 12.1 2.2e-07 31.2 0.1 6.2 5 1 1 6 6 6 5 Cadherin domain Cadherin_4 PF17803.1 RUS86169.1 - 0.65 10.7 21.0 0.57 10.8 0.5 5.7 5 1 0 5 5 5 0 Bacterial cadherin-like domain Exo_endo_phos_2 PF14529.6 RUS86170.1 - 1.4e-13 50.8 0.0 3.2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDHD PF02862.17 RUS86170.1 - 0.0036 17.5 3.9 0.0039 17.4 2.8 1.8 2 0 0 2 2 2 1 DDHD domain PHD PF00628.29 RUS86170.1 - 0.0054 16.6 16.6 0.019 14.9 16.6 2.0 1 0 0 1 1 1 1 PHD-finger Exo_endo_phos PF03372.23 RUS86170.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4228 PF14009.6 RUS86170.1 - 0.009 16.4 3.1 0.015 15.7 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) RMP PF14996.6 RUS86170.1 - 0.031 14.5 19.4 0.075 13.2 19.4 1.6 1 0 0 1 1 1 0 Retinal Maintenance NPR3 PF03666.13 RUS86170.1 - 0.3 9.8 22.6 0.5 9.1 22.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 RUS86170.1 - 0.33 10.4 17.4 0.55 9.6 17.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RP-C_C PF11800.8 RUS86170.1 - 0.36 10.9 4.9 0.63 10.1 3.5 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region RAB3GAP2_C PF14656.6 RUS86170.1 - 0.38 8.9 5.9 0.78 7.9 5.9 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Zip PF02535.22 RUS86170.1 - 0.42 9.8 8.0 0.7 9.1 8.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PRC2_HTH_1 PF18118.1 RUS86170.1 - 0.45 11.4 18.3 1.6 9.6 18.3 2.0 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain SLC12 PF03522.15 RUS86170.1 - 0.57 9.1 16.2 0.93 8.4 16.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 YL1 PF05764.13 RUS86170.1 - 0.59 10.2 32.6 1.1 9.3 32.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Tim54 PF11711.8 RUS86170.1 - 0.78 8.5 19.4 1.2 7.8 19.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 RUS86170.1 - 1 8.1 7.2 1.5 7.6 7.2 1.2 1 0 0 1 1 1 0 Otopetrin DUF1168 PF06658.12 RUS86170.1 - 1.1 9.1 42.7 2.4 8.0 42.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Vfa1 PF08432.10 RUS86170.1 - 1.6 9.0 37.0 3.1 8.1 37.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LicD PF04991.13 RUS86170.1 - 2 8.5 21.0 3.7 7.6 21.0 1.4 1 0 0 1 1 1 0 LicD family Gti1_Pac2 PF09729.9 RUS86170.1 - 2 8.4 21.2 3.4 7.7 20.1 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family IHABP4_N PF16174.5 RUS86170.1 - 2.1 8.9 35.4 0.28 11.8 31.1 1.7 2 0 0 2 2 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3807 PF12720.7 RUS86170.1 - 2.3 8.4 27.4 4.8 7.4 27.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RPOL_N PF14700.6 RUS86170.1 - 2.6 7.3 20.9 4.5 6.6 20.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal eIF3_subunit PF08597.10 RUS86170.1 - 2.8 7.8 35.6 5.2 6.9 35.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 RUS86170.1 - 3.3 5.9 20.0 12 4.0 20.8 1.4 2 0 0 2 2 2 0 CDC45-like protein Connexin PF00029.19 RUS86170.1 - 4.1 7.1 20.2 7.2 6.3 20.2 1.3 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 RUS86170.1 - 4.9 7.3 15.9 11 6.2 15.9 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 RUS86170.1 - 7.4 7.0 23.4 19 5.6 22.5 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF716 PF04819.12 RUS86171.1 - 1.7e-23 82.8 5.6 2.5e-23 82.2 5.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF716) SCIMP PF15050.6 RUS86171.1 - 0.0057 17.1 0.0 0.0097 16.4 0.0 1.3 1 0 0 1 1 1 1 SCIMP protein ABC_membrane_3 PF13748.6 RUS86171.1 - 0.01 15.1 0.3 0.018 14.3 0.0 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region MLANA PF14991.6 RUS86171.1 - 0.068 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A MASE5 PF17178.4 RUS86171.1 - 0.31 10.9 8.1 1.1 9.0 8.1 1.8 1 1 0 1 1 1 0 Membrane-associated sensor DUF4131 PF13567.6 RUS86171.1 - 4.4 6.9 5.9 2e+02 1.6 5.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.24 RUS86172.1 - 6e-32 111.1 18.3 9.3e-32 110.5 18.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS86172.1 - 6.3e-25 87.8 33.8 1.4e-12 47.3 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MOLO1 PF17175.4 RUS86173.1 - 5.7e-19 68.4 0.0 2.1e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 Frizzled PF01534.17 RUS86174.1 - 1e-130 435.6 5.7 1.4e-130 435.1 5.7 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RUS86174.1 - 1.1e-27 96.9 5.0 3.1e-27 95.4 5.0 1.8 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 RUS86174.1 - 0.0018 17.5 3.8 0.003 16.7 3.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor IATP PF04568.12 RUS86174.1 - 0.051 14.0 6.6 0.11 12.9 6.6 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF1358 PF07096.11 RUS86177.1 - 2.2e-34 117.9 0.3 2.9e-34 117.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) EutH PF04346.12 RUS86177.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH RCC1 PF00415.18 RUS86178.1 - 9.2e-69 227.9 11.1 3.2e-12 46.9 0.2 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS86178.1 - 1.2e-43 146.1 14.7 4.6e-08 32.7 0.2 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 RUS86178.1 - 0.13 12.6 1.4 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Kelch motif PQQ_3 PF13570.6 RUS86178.1 - 0.17 12.4 1.3 33 5.2 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain Cystatin PF00031.21 RUS86179.1 - 7.7e-19 67.8 6.0 3.8e-09 36.7 1.3 2.4 1 1 1 2 2 2 2 Cystatin domain SQAPI PF16845.5 RUS86179.1 - 0.00074 19.8 2.2 0.29 11.5 0.8 2.2 1 1 1 2 2 2 2 Aspartic acid proteinase inhibitor Ribosomal_L18_c PF14204.6 RUS86179.1 - 0.26 12.2 6.2 4.4 8.3 0.4 2.3 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region Tmp39 PF10271.9 RUS86180.1 - 8.7e-128 427.0 18.5 1.3e-127 426.5 18.5 1.2 1 0 0 1 1 1 1 Putative transmembrane protein Gly_transf_sug PF04488.15 RUS86182.1 - 8e-06 26.4 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS86182.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 RUS86182.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain zf-H2C2_2 PF13465.6 RUS86184.1 - 0.00049 20.4 1.0 0.00049 20.4 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86184.1 - 0.0092 16.4 5.9 0.0092 16.4 5.9 3.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 RUS86184.1 - 0.27 11.1 2.4 0.8 9.5 2.4 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS86184.1 - 1.5 9.2 5.2 2.5 8.5 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Lectin_C PF00059.21 RUS86187.1 - 2.6e-12 47.4 6.9 3.5e-08 34.1 0.4 3.0 2 1 1 3 3 3 2 Lectin C-type domain SR-25 PF10500.9 RUS86188.1 - 1.1 8.8 11.8 1.4 8.5 11.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.6 RUS86189.1 - 1e-51 171.1 68.6 3.6e-08 33.5 0.2 10.7 11 0 0 11 11 10 10 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86189.1 - 3.1e-43 143.9 65.7 0.00021 21.5 0.3 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86189.1 - 9.2e-36 119.4 63.7 0.00058 20.5 0.1 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS86189.1 - 1.1e-19 70.1 30.9 0.024 14.9 0.1 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS86189.1 - 7e-18 64.2 54.4 0.0026 17.7 1.0 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-met PF12874.7 RUS86189.1 - 4.1e-14 52.4 39.0 0.0085 16.5 0.6 10.0 10 0 0 10 10 10 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS86189.1 - 6.7e-07 29.5 38.7 0.0032 17.7 1.2 6.9 4 2 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 RUS86189.1 - 8.2e-06 25.6 39.7 0.067 13.1 0.1 10.0 10 0 0 10 10 10 2 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RUS86189.1 - 0.00027 21.0 36.3 0.55 10.4 2.1 7.7 5 2 3 8 8 8 4 Zinc ribbon domain BolA PF01722.18 RUS86189.1 - 0.012 15.9 11.6 8.3 6.8 0.6 6.2 4 2 0 4 4 4 0 BolA-like protein GAGA PF09237.11 RUS86189.1 - 0.024 14.4 10.0 0.21 11.4 0.1 4.5 4 1 1 5 5 5 0 GAGA factor zf-C2H2_3rep PF18868.1 RUS86189.1 - 0.07 13.8 0.8 0.07 13.8 0.8 7.1 2 1 1 4 4 3 0 Zinc finger C2H2-type, 3 repeats Flag1_repress PF03614.13 RUS86189.1 - 0.074 12.8 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Repressor of phase-1 flagellin HCV_env PF01539.17 RUS86189.1 - 0.078 12.7 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 zf_UBZ PF18439.1 RUS86189.1 - 0.081 12.5 33.4 4.5 7.0 0.1 9.0 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 RUS86189.1 - 0.26 11.6 43.8 4.3 7.7 2.9 8.0 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 RUS86189.1 - 2.2 9.1 28.4 1.7 9.4 1.3 5.8 1 1 2 4 4 4 0 zinc-ribbon family zf-FCS PF06467.14 RUS86189.1 - 2.5 8.1 22.8 0.57 10.2 1.4 6.3 5 1 1 6 6 6 0 MYM-type Zinc finger with FCS sequence motif TRAF6_Z2 PF18048.1 RUS86189.1 - 2.5 8.3 0.0 2.5 8.3 0.0 4.3 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 7tm_1 PF00001.21 RUS86190.1 - 1.2e-12 47.7 1.1 1.9e-12 47.1 1.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS86190.1 - 2e-05 24.1 0.4 2.8e-05 23.6 0.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS86191.1 - 8.3e-63 212.2 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS86191.1 - 9.5e-12 44.8 8.8 1.3e-05 24.7 0.9 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS86191.1 - 4.2e-09 36.2 8.3 2.1e-06 27.3 1.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS86191.1 - 9.1e-08 32.0 3.8 9.1e-08 32.0 3.8 2.0 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GRP PF07172.11 RUS86191.1 - 0.00049 20.7 7.1 0.00049 20.7 7.1 4.6 4 0 0 4 4 4 1 Glycine rich protein family 7tm_4 PF13853.6 RUS86191.1 - 0.00057 19.7 5.4 0.021 14.6 0.3 2.9 2 1 1 3 3 3 2 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 RUS86191.1 - 0.0057 16.2 1.2 0.0057 16.2 1.2 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF996 PF06195.13 RUS86191.1 - 0.012 15.9 3.9 0.32 11.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Saf_2TM PF18303.1 RUS86191.1 - 0.083 12.5 0.4 0.18 11.4 0.4 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain 7TM_GPCR_Srsx PF10320.9 RUS86192.1 - 2.3e-10 40.3 11.3 4e-10 39.5 11.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS86192.1 - 4e-09 36.2 13.8 5.1e-09 35.8 13.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86192.1 - 4.3e-07 29.5 12.8 1.5e-06 27.8 12.8 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS86192.1 - 3.3e-06 26.9 15.5 3.3e-06 26.9 15.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Lectin_C PF00059.21 RUS86193.1 - 0.0037 18.0 0.0 0.0083 16.8 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS86193.1 - 0.014 15.3 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 PAN domain SH3_3 PF08239.11 RUS86194.1 - 0.0064 16.8 1.0 0.015 15.6 1.0 1.6 1 1 0 1 1 1 1 Bacterial SH3 domain Orf78 PF06024.12 RUS86196.1 - 0.00079 19.7 3.5 0.0015 18.8 3.2 1.7 1 1 0 1 1 1 1 Orf78 (ac78) Plasmodium_Vir PF05795.11 RUS86196.1 - 0.0038 16.7 13.6 0.0049 16.3 13.6 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF4690 PF15756.5 RUS86196.1 - 0.0041 17.7 2.7 0.0041 17.7 2.7 3.0 2 2 1 3 3 3 1 Small Novel Rich in Cartilage TMEM132D_C PF15706.5 RUS86196.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ABC2_membrane_3 PF12698.7 RUS86196.1 - 0.017 14.2 9.3 0.019 14.1 8.5 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Syndecan PF01034.20 RUS86196.1 - 0.046 13.7 0.2 0.096 12.6 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 RUS86196.1 - 0.052 13.4 1.8 0.07 13.0 1.8 1.2 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 RUS86196.1 - 0.11 12.3 0.6 0.22 11.3 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GREB1 PF15782.5 RUS86196.1 - 0.2 8.8 9.5 0.26 8.3 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 RUS86196.1 - 0.26 10.0 3.2 0.46 9.2 3.2 1.4 1 0 0 1 1 1 0 Presenilin Otopetrin PF03189.13 RUS86196.1 - 0.35 9.6 3.7 0.13 11.0 0.5 1.6 1 1 1 2 2 2 0 Otopetrin Podoplanin PF05808.11 RUS86196.1 - 0.36 10.9 11.2 0.051 13.7 6.8 1.8 2 0 0 2 2 2 0 Podoplanin Glyco_hydro_16 PF00722.21 RUS86197.1 - 6e-08 32.4 0.0 9.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SDA1 PF05285.12 RUS86197.1 - 0.0017 17.9 26.5 0.002 17.7 26.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS86197.1 - 0.0053 15.1 27.2 0.0063 14.8 27.2 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 RUS86197.1 - 1.7 7.4 4.2 1.9 7.2 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 RUS86197.1 - 3.3 7.5 5.5 4.7 7.0 5.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 RUS86198.1 - 5.2 5.7 4.8 5.1 5.8 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 RUS86200.1 - 0.6 8.3 66.3 0.17 10.2 29.6 2.2 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 RUS86200.1 - 7 6.0 84.5 0.72 9.2 36.7 2.0 2 0 0 2 2 2 0 SDA1 Patatin PF01734.22 RUS86201.1 - 3.1e-28 99.3 0.1 7.1e-28 98.2 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Zip PF02535.22 RUS86201.1 - 0.059 12.6 16.2 0.093 11.9 16.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 RUS86201.1 - 0.29 9.9 4.1 0.39 9.5 4.1 1.2 1 0 0 1 1 1 0 Otopetrin EF-hand_6 PF13405.6 RUS86202.1 - 3.3e-06 26.6 0.1 9.9e-06 25.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RUS86202.1 - 8.3e-06 25.0 0.5 2.3e-05 23.6 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 RUS86202.1 - 0.0001 21.6 0.3 0.00019 20.8 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RUS86202.1 - 0.00042 20.1 0.4 0.0021 17.9 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS86202.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair Toprim_2 PF13155.6 RUS86202.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Toprim-like 7tm_3 PF00003.22 RUS86203.1 - 5.7e-33 114.6 23.2 7.3e-33 114.3 23.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR TRAP_alpha PF03896.16 RUS86203.1 - 4.2 6.5 5.4 6.7 5.8 5.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NusB PF01029.18 RUS86205.1 - 0.12 12.7 0.2 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 NusB family CBM_14 PF01607.24 RUS86206.1 - 5e-08 33.0 4.8 5e-08 33.0 4.8 1.6 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.27 RUS86208.1 - 1.9e-46 158.7 1.8 1.5e-45 155.8 1.8 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS86208.1 - 7.7e-13 49.3 0.0 2e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family MCM_N PF14551.6 RUS86208.1 - 0.017 15.7 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 MCM N-terminal domain YadA_anchor PF03895.15 RUS86210.1 - 0.005 16.9 11.0 0.032 14.3 0.3 2.6 3 0 0 3 3 3 2 YadA-like membrane anchor domain cNMP_binding PF00027.29 RUS86211.1 - 1.2e-18 67.0 0.1 1e-14 54.3 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain CDC45 PF02724.14 RUS86211.1 - 0.29 9.4 22.0 0.73 8.1 22.0 1.6 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS86211.1 - 0.87 9.0 27.3 0.02 14.4 20.2 1.8 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 RUS86211.1 - 7 4.7 33.7 0.0052 15.1 19.5 2.3 2 1 1 3 3 3 0 Nop14-like family SNF PF00209.18 RUS86212.1 - 1.4e-219 730.2 38.3 7e-219 727.8 38.3 1.8 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family F-box-like PF12937.7 RUS86213.1 - 4.9e-07 29.5 0.4 1.2e-06 28.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 RUS86213.1 - 0.14 11.7 1.9 1.9 8.1 0.5 2.4 2 0 0 2 2 2 0 F-box TPR_1 PF00515.28 RUS86214.1 - 2.5e-08 33.4 0.0 0.0072 16.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS86214.1 - 8e-06 25.6 3.0 0.073 13.2 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS86214.1 - 0.0047 17.0 0.5 0.0047 17.0 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS86214.1 - 0.013 15.7 0.1 0.51 10.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS86214.1 - 0.051 13.9 1.9 1.3 9.3 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS86214.1 - 0.057 13.1 4.7 7.5 6.3 0.0 4.2 6 0 0 6 6 6 0 TPR repeat CSN5_C PF18323.1 RUS86214.1 - 0.11 13.4 0.0 0.22 12.5 0.0 1.5 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Rhodanese PF00581.20 RUS86215.1 - 4.2e-09 36.9 0.0 8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Sugar_tr PF00083.24 RUS86216.1 - 2.9e-28 98.9 14.4 4.2e-28 98.4 14.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS86216.1 - 5.4e-17 61.7 18.9 9.6e-17 60.9 18.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1345 PF07077.11 RUS86216.1 - 0.017 14.8 1.1 0.48 10.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Ribophorin_I PF04597.14 RUS86217.1 - 6.4e-143 477.1 8.0 8.7e-143 476.7 8.0 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 RUS86217.1 - 3.7e-05 24.3 1.5 9e-05 23.1 1.5 1.6 1 0 0 1 1 1 1 DNA repair REX1-B FlxA PF14282.6 RUS86217.1 - 0.01 15.8 3.4 0.01 15.8 3.4 1.9 2 0 0 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 RUS86217.1 - 0.013 15.7 0.9 2.4 8.5 1.7 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 RUS86217.1 - 0.065 13.6 4.5 0.14 12.5 4.5 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HopJ PF08888.11 RUS86217.1 - 0.14 12.4 0.5 0.49 10.6 0.2 2.0 2 0 0 2 2 2 0 HopJ type III effector protein DUF737 PF05300.11 RUS86217.1 - 0.48 10.8 4.9 1.3 9.3 4.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF4407 PF14362.6 RUS86217.1 - 0.72 9.1 6.2 1.2 8.4 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IBN_N PF03810.19 RUS86218.1 - 5.1e-12 45.5 0.0 1.9e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RUS86218.1 - 7.3e-06 26.1 11.8 1.9e-05 24.8 0.0 5.4 6 1 1 7 7 7 1 Exportin 1-like protein MMS19_C PF12460.8 RUS86218.1 - 3.1e-05 23.3 4.4 0.3 10.1 0.0 3.6 3 0 0 3 3 3 3 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 RUS86218.1 - 0.00039 20.3 0.2 0.65 9.9 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Cse1 PF08506.10 RUS86218.1 - 0.00079 18.4 0.3 0.005 15.7 0.1 2.2 1 1 1 2 2 2 1 Cse1 RIX1 PF08167.12 RUS86218.1 - 0.0008 19.2 0.8 1.3 8.7 0.1 3.9 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 RUS86218.1 - 0.0016 18.4 7.2 0.58 10.0 0.1 4.5 3 2 1 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal MutL_C PF08676.11 RUS86218.1 - 0.076 12.8 0.0 1 9.1 0.1 2.6 2 0 0 2 2 2 0 MutL C terminal dimerisation domain DUF2457 PF10446.9 RUS86218.1 - 2.5 7.1 10.8 3.9 6.5 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bromo_TP PF07524.13 RUS86219.1 - 2.5e-22 78.7 0.0 3.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 RUS86219.1 - 1.4e-11 44.0 7.7 4e-11 42.6 7.7 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS86219.1 - 0.0032 17.0 2.7 0.0032 17.0 2.7 2.2 2 0 0 2 2 2 1 PHD-finger Bromo_TP_like PF17027.5 RUS86219.1 - 0.023 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Histone-fold protein TFIID-31kDa PF02291.15 RUS86219.1 - 0.025 14.7 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Arf PF00025.21 RUS86220.1 - 2.9e-51 173.4 0.0 3.5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS86220.1 - 2.2e-11 43.6 0.0 2.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RUS86220.1 - 1.4e-10 40.9 0.3 0.00011 21.6 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 RUS86220.1 - 4.1e-10 39.9 0.0 5.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS86220.1 - 4e-07 29.6 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS86220.1 - 4.7e-07 29.9 0.0 7.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS86220.1 - 4.7e-05 23.0 0.0 0.0016 18.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RUS86220.1 - 4.8e-05 22.8 0.0 6.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 RUS86220.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Bacterial TniB protein Dynamin_N PF00350.23 RUS86220.1 - 0.0089 16.1 0.0 1.7 8.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.6 RUS86220.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RUS86220.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 RUS86220.1 - 0.037 13.6 0.2 0.31 10.6 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 RUS86220.1 - 0.067 13.6 0.1 1.2 9.5 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Septin PF00735.18 RUS86220.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.18 RUS86220.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family VGCC_alpha2 PF08473.11 RUS86221.1 - 2.9e-59 201.0 14.0 2.9e-49 168.0 2.8 2.3 1 1 1 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 RUS86221.1 - 8.1e-31 107.1 0.7 3.6e-30 105.0 0.1 2.5 2 0 0 2 2 2 1 VWA N-terminal VWA PF00092.28 RUS86221.1 - 3.9e-13 50.0 0.0 7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS86221.1 - 1.2e-11 44.8 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 RUS86221.1 - 2.6e-08 34.0 1.7 6.5e-07 29.4 0.1 3.0 4 0 0 4 4 4 1 Cache domain Cache_3-Cache_2 PF17201.4 RUS86221.1 - 0.023 14.0 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain DUF4560 PF15118.6 RUS86221.1 - 0.08 12.9 0.4 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) FAM150 PF15129.6 RUS86221.1 - 2.9 8.0 7.0 9 6.5 0.7 2.7 2 0 0 2 2 2 0 FAM150 family Ima1_N PF09779.9 RUS86221.1 - 6.3 7.7 9.8 1.2e+02 3.5 10.0 2.7 1 1 0 1 1 1 0 Ima1 N-terminal domain cNMP_binding PF00027.29 RUS86223.1 - 1.1e-20 73.5 0.2 3.7e-15 55.8 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain NOA36 PF06524.12 RUS86223.1 - 0.0044 16.4 16.1 0.0096 15.3 16.1 1.5 1 0 0 1 1 1 1 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 RUS86223.1 - 0.0051 17.1 8.6 0.0051 17.1 8.6 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Adhesin_E PF16747.5 RUS86223.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Surface-adhesin protein E RXT2_N PF08595.11 RUS86223.1 - 0.2 11.7 8.8 0.045 13.8 4.9 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 RUS86223.1 - 0.28 10.5 5.0 0.7 9.2 5.0 1.6 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS86223.1 - 0.51 8.5 9.0 0.88 7.7 9.0 1.3 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS86223.1 - 0.7 9.2 9.3 1.3 8.4 9.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 RUS86223.1 - 1.1 8.9 5.5 2.4 7.9 5.5 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 RUS86223.1 - 2.9 7.4 12.2 0.53 9.8 8.1 1.8 2 0 0 2 2 2 0 PPP4R2 NDUF_B12 PF08122.12 RUS86224.1 - 0.098 12.7 0.2 12 6.0 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family SKG6 PF08693.10 RUS86224.1 - 1.3 8.5 0.0 1.3 8.5 0.0 3.2 3 0 0 3 3 3 0 Transmembrane alpha-helix domain zf-UBP PF02148.19 RUS86225.1 - 3.1e-18 65.9 8.0 4.4e-18 65.4 8.0 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 RUS86225.1 - 0.012 15.3 0.5 0.022 14.5 0.5 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger zinc_ribbon_9 PF14369.6 RUS86225.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.3 3 1 0 4 4 4 0 zinc-ribbon Astacin PF01400.24 RUS86226.1 - 5.4e-17 62.0 0.0 8.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) 7tm_1 PF00001.21 RUS86228.1 - 1.4e-29 103.3 10.9 1.4e-29 103.3 10.9 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS86228.1 - 2e-08 34.2 6.9 2.7e-08 33.8 6.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS86228.1 - 3.7e-07 29.8 6.9 4.8e-07 29.4 6.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YrhC PF14143.6 RUS86228.1 - 1.8 8.7 3.5 19 5.4 0.0 3.1 3 0 0 3 3 3 0 YrhC-like protein AIG1 PF04548.16 RUS86229.1 - 1.6e-10 40.7 0.2 1.8e-10 40.5 0.2 1.0 1 0 0 1 1 1 1 AIG1 family 7tm_1 PF00001.21 RUS86230.1 - 1e-06 28.3 17.8 1.3e-06 27.9 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS86230.1 - 2.4 7.7 37.7 0.012 15.2 23.5 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx BORCS6 PF10157.9 RUS86231.1 - 1.3e-30 106.6 1.0 3e-30 105.5 1.0 1.6 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Miga PF10265.9 RUS86231.1 - 0.63 8.9 2.7 0.92 8.4 2.7 1.2 1 0 0 1 1 1 0 Mitoguardin PDZ PF00595.24 RUS86232.1 - 3.3e-23 81.9 0.3 4.9e-12 46.0 0.1 2.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 RUS86232.1 - 4.5e-17 61.6 0.1 4.6e-07 29.6 0.2 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS86232.1 - 9e-12 45.2 0.3 2.7e-05 24.4 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_4 PF17816.1 RUS86232.1 - 0.15 12.5 0.1 2.2 8.7 0.0 2.5 2 1 0 2 2 2 0 PDZ domain PDZ PF00595.24 RUS86233.1 - 3e-08 33.9 0.0 5.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS86233.1 - 7.5e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS86233.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Transglut_core PF01841.19 RUS86235.1 - 0.00031 21.2 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily ParD_antitoxin PF03693.14 RUS86235.1 - 0.026 14.9 0.2 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF3704 PF12488.8 RUS86235.1 - 0.37 10.5 5.7 8.1 6.2 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Metallophos PF00149.28 RUS86236.1 - 4.7e-13 50.1 0.7 6.6e-13 49.6 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RUS86236.1 - 6.7e-11 42.7 0.0 2.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DFP PF04127.15 RUS86237.1 - 1.9e-19 70.2 0.0 2.3e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Gemini_mov PF01708.16 RUS86239.1 - 0.063 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein NIDO PF06119.14 RUS86241.1 - 3.6e-06 27.8 0.7 1e-05 26.4 0.7 1.8 1 0 0 1 1 1 1 Nidogen-like ZU5 PF00791.20 RUS86241.1 - 0.00091 19.5 27.9 4.8 7.6 1.2 6.5 1 1 6 7 7 7 6 ZU5 domain VWD PF00094.25 RUS86241.1 - 0.011 16.1 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type D domain cEGF PF12662.7 RUS86242.1 - 3.6e-22 77.9 49.0 1.5e-08 34.4 0.7 6.6 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS86242.1 - 1.3e-20 73.3 40.3 1.2e-09 38.2 8.4 6.9 5 2 2 7 7 7 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS86242.1 - 5.7e-14 52.1 64.4 0.00022 21.4 7.0 6.0 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site VWD PF00094.25 RUS86242.1 - 1.4e-06 28.7 0.9 1.5e-05 25.3 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type D domain EGF_MSP1_1 PF12946.7 RUS86242.1 - 4.3e-06 26.7 13.7 7.7e-06 25.9 5.5 6.1 5 1 0 5 5 5 2 MSP1 EGF domain 1 hEGF PF12661.7 RUS86242.1 - 4.8e-05 23.8 15.5 0.0012 19.4 4.0 7.3 9 0 0 9 9 9 2 Human growth factor-like EGF EGF_3 PF12947.7 RUS86242.1 - 0.00035 20.7 5.1 0.00035 20.7 5.1 7.4 3 1 3 6 6 6 2 EGF domain EGF_2 PF07974.13 RUS86242.1 - 0.003 17.9 1.0 0.003 17.9 1.0 6.4 5 2 0 5 5 5 1 EGF-like domain EGF PF00008.27 RUS86242.1 - 0.012 15.9 2.7 0.012 15.9 2.7 7.5 7 2 0 7 7 7 0 EGF-like domain LBR_tudor PF09465.10 RUS86242.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain EGF_CA PF07645.15 RUS86243.1 - 1.7e-45 152.9 139.5 7e-11 42.1 8.2 9.7 9 0 0 9 9 9 7 Calcium-binding EGF domain cEGF PF12662.7 RUS86243.1 - 1.6e-27 95.1 89.6 9.8e-07 28.6 1.7 11.5 11 0 0 11 11 11 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS86243.1 - 2.3e-22 79.0 129.6 1e-07 32.1 9.6 9.9 7 3 2 9 9 9 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS86243.1 - 3.2e-08 33.7 121.9 0.006 16.9 5.4 11.1 8 2 2 10 10 10 6 EGF-like domain EGF_MSP1_1 PF12946.7 RUS86243.1 - 7.7e-07 29.1 5.6 7.7e-07 29.1 5.6 9.1 10 0 0 10 10 10 3 MSP1 EGF domain 1 DSL PF01414.19 RUS86243.1 - 0.0003 21.0 15.3 0.0003 21.0 15.3 8.1 5 1 5 10 10 10 1 Delta serrate ligand EGF_3 PF12947.7 RUS86243.1 - 0.0026 17.9 8.3 0.0026 17.9 8.3 10.5 9 2 0 9 9 9 6 EGF domain Plasmod_Pvs28 PF06247.11 RUS86243.1 - 0.016 15.5 5.7 0.016 15.5 5.7 9.7 9 1 0 9 9 9 0 Pvs28 EGF domain hEGF PF12661.7 RUS86243.1 - 0.023 15.4 0.6 0.023 15.4 0.6 13.3 11 1 1 12 12 12 0 Human growth factor-like EGF Herpes_gE PF02480.16 RUS86244.1 - 0.0038 16.0 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 RUS86244.1 - 0.0047 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.10 RUS86244.1 - 0.0089 15.4 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LST1 PF05083.13 RUS86244.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein DUF4448 PF14610.6 RUS86244.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 RUS86244.1 - 0.1 13.5 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 RUS86244.1 - 0.21 12.2 0.0 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF4620 PF15399.6 RUS86244.1 - 3.5 8.0 9.4 0.67 10.3 4.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4620) Fibrinogen_C PF00147.18 RUS86246.1 - 5e-23 82.1 1.8 1.1e-12 48.2 0.0 2.0 1 1 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain bZIP_1 PF00170.21 RUS86248.1 - 2.5e-12 46.7 8.2 5.5e-12 45.6 8.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS86248.1 - 4.9e-09 36.1 8.5 1.3e-08 34.7 8.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS86248.1 - 3.2e-05 24.4 5.3 3.2e-05 24.4 5.3 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor zf-C2H2 PF00096.26 RUS86248.1 - 0.0057 17.0 0.4 0.0057 17.0 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type TonB_2 PF13103.6 RUS86248.1 - 0.023 14.9 0.3 7.2 6.9 0.0 2.8 2 0 0 2 2 2 0 TonB C terminal DivIC PF04977.15 RUS86248.1 - 0.77 9.6 9.6 0.13 12.1 1.7 2.5 2 0 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.14 RUS86248.1 - 1.1 9.7 9.4 0.14 12.6 0.9 2.7 2 0 0 2 2 2 0 Nnf1 HALZ PF02183.18 RUS86248.1 - 1.1 9.6 4.5 1 9.7 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 RUS86248.1 - 2 7.7 13.2 5.8 6.2 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 RUS86248.1 - 9 6.8 14.9 0.063 13.7 2.4 2.9 3 0 0 3 3 3 0 Cell division protein ZapB IPPT PF01715.17 RUS86250.1 - 9.8e-25 87.7 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 RUS86250.1 - 1.4e-06 27.8 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 RUS86250.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RUS86250.1 - 0.0066 16.8 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 RUS86250.1 - 0.015 15.7 0.1 0.022 15.2 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 RUS86250.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 RUS86250.1 - 0.026 15.0 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 RUS86250.1 - 0.03 13.6 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin Hydin_ADK PF17213.3 RUS86250.1 - 0.036 14.3 0.1 0.045 14.0 0.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 RUS86250.1 - 0.041 13.6 0.1 0.045 13.5 0.1 1.2 1 1 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 RUS86250.1 - 0.082 12.3 0.1 0.082 12.3 0.1 1.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 RUS86250.1 - 0.083 13.4 0.0 0.092 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 RUS86250.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 RUS86250.1 - 0.17 12.1 0.0 0.35 11.2 0.0 1.6 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 RUS86250.1 - 0.24 11.3 0.2 0.31 10.9 0.2 1.5 1 1 0 1 1 1 0 NACHT domain HLH PF00010.26 RUS86251.1 - 9.8e-13 47.9 1.8 2.2e-12 46.8 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VPDSG-CTERM PF18205.1 RUS86253.1 - 5.2e-07 29.3 35.8 0.72 9.7 0.1 10.8 11 1 1 12 12 12 10 VPDSG-CTERM motif 7tm_6 PF02949.20 RUS86254.1 - 1.8e-08 33.8 1.8 4.9e-08 32.4 1.2 1.9 1 1 0 1 1 1 1 7tm Odorant receptor 7tm_7 PF08395.12 RUS86254.1 - 2.8e-05 23.5 0.8 2.8e-05 23.5 0.8 2.5 2 1 1 3 3 3 1 7tm Chemosensory receptor Oxidored_q2 PF00420.24 RUS86254.1 - 0.2 11.3 0.1 0.2 11.3 0.1 3.1 3 1 1 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MAS20 PF02064.15 RUS86255.1 - 2.4e-43 147.3 0.1 4.1e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor Ring_hydroxyl_A PF00848.19 RUS86255.1 - 0.0079 16.2 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Pkinase PF00069.25 RUS86256.1 - 3e-77 259.6 0.0 6.1e-77 258.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86256.1 - 1.8e-38 132.4 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 RUS86256.1 - 2.8e-15 56.7 0.5 7e-15 55.4 0.5 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 RUS86256.1 - 9.8e-09 34.9 0.0 2.1e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.6 RUS86256.1 - 0.00013 22.4 1.6 0.00058 20.2 1.3 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain FTA2 PF13095.6 RUS86256.1 - 0.0045 16.6 0.2 0.23 11.0 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RUS86256.1 - 0.0085 15.1 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Adap_comp_sub PF00928.21 RUS86257.1 - 6.8e-28 97.8 0.0 8.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS86257.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain WD40 PF00400.32 RUS86258.1 - 7.9e-11 42.3 5.7 6.5e-08 33.1 0.0 3.9 3 1 1 4 4 4 2 WD domain, G-beta repeat Frtz PF11768.8 RUS86258.1 - 0.002 16.5 0.4 0.0028 16.0 0.4 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 PF12894.7 RUS86258.1 - 0.0072 16.6 0.0 1.3 9.4 0.0 3.1 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C4 PF00105.18 RUS86260.1 - 3.2e-31 107.6 11.6 6.9e-31 106.5 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS86260.1 - 3.3e-28 98.7 0.3 5.5e-28 98.0 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PAN_1 PF00024.26 RUS86261.1 - 7.8e-15 54.6 21.9 6.5e-07 29.2 1.3 4.0 4 0 0 4 4 4 3 PAN domain PAN_4 PF14295.6 RUS86261.1 - 0.63 10.0 20.6 1.8 8.5 1.2 4.2 4 0 0 4 4 4 0 PAN domain PLAT PF01477.23 RUS86263.1 - 2.3e-51 173.3 8.1 2.6e-17 63.4 0.2 3.8 4 0 0 4 4 4 3 PLAT/LH2 domain ATS3 PF06232.11 RUS86263.1 - 3.3e-08 33.5 1.2 0.031 14.2 0.5 3.2 3 0 0 3 3 3 3 Embryo-specific protein 3, (ATS3) RNA_pol_Rpb4 PF03874.16 RUS86263.1 - 0.1 13.0 1.1 0.23 11.8 1.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb4 MaoC_dehydratas PF01575.19 RUS86263.1 - 0.12 12.0 0.1 0.44 10.1 0.0 1.9 3 0 0 3 3 3 0 MaoC like domain Vpu PF00558.19 RUS86263.1 - 0.12 12.1 1.0 0.38 10.5 1.0 1.8 1 0 0 1 1 1 0 Vpu protein SRP14 PF02290.15 RUS86264.1 - 9.2e-25 86.9 0.0 1.3e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein eIF-4B PF06273.11 RUS86264.1 - 0.0013 17.9 0.0 0.0015 17.7 0.0 1.0 1 0 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B AhpC-TSA_2 PF13911.6 RUS86265.1 - 0.076 13.1 0.6 0.25 11.5 0.6 2.1 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme ASC PF00858.24 RUS86266.1 - 6.4e-50 170.4 0.7 2.8e-49 168.3 0.7 1.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3341 PF11821.8 RUS86266.1 - 0.055 13.1 2.1 0.12 12.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Lectin_C PF00059.21 RUS86267.1 - 2.6e-15 57.1 6.0 8.3e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain DDHD PF02862.17 RUS86267.1 - 0.008 16.4 1.2 0.008 16.4 1.2 1.1 1 0 0 1 1 1 1 DDHD domain DUF4471 PF14740.6 RUS86267.1 - 0.085 12.1 6.8 0.11 11.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4614 PF15391.6 RUS86267.1 - 0.2 11.6 4.5 2.8 7.9 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Connexin PF00029.19 RUS86267.1 - 0.33 10.7 14.0 0.4 10.4 14.0 1.2 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 RUS86267.1 - 0.37 10.2 11.6 0.44 10.0 11.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 RUS86267.1 - 0.39 10.8 13.7 0.57 10.2 13.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Zip PF02535.22 RUS86267.1 - 0.57 9.3 2.5 0.54 9.4 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 RUS86267.1 - 0.62 8.8 3.3 0.64 8.8 3.3 1.1 1 0 0 1 1 1 0 Otopetrin Sec62 PF03839.16 RUS86267.1 - 0.72 9.3 19.9 0.95 8.9 19.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MDM10 PF12519.8 RUS86267.1 - 0.93 8.3 7.1 1.1 8.1 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4770 PF15994.5 RUS86267.1 - 0.98 9.6 15.9 1.2 9.3 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Tim54 PF11711.8 RUS86267.1 - 1.1 7.9 14.7 1.3 7.7 14.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 RUS86267.1 - 1.4 7.6 7.2 1.6 7.4 7.2 1.1 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 RUS86267.1 - 1.6 7.9 12.7 2 7.7 12.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RPN2_C PF18004.1 RUS86267.1 - 2.5 8.0 30.3 3.4 7.6 30.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MAS20 PF02064.15 RUS86267.1 - 2.8 8.1 16.6 4.6 7.4 16.6 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor YL1 PF05764.13 RUS86267.1 - 2.9 7.9 28.6 3.6 7.6 28.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein OATP PF03137.20 RUS86267.1 - 4.1 5.6 11.5 4.6 5.4 11.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DAG_kinase_N PF14513.6 RUS86267.1 - 5.1 7.3 16.0 9.9 6.3 15.6 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Rxt3 PF08642.10 RUS86267.1 - 5.9 7.7 7.6 8.9 7.1 7.6 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Neur_chan_memb PF02932.16 RUS86267.1 - 6.6 6.7 8.3 8.1 6.4 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RPOL_N PF14700.6 RUS86267.1 - 6.8 6.0 17.1 8.1 5.7 17.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal LicD PF04991.13 RUS86267.1 - 7.3 6.6 16.6 9.9 6.2 16.6 1.2 1 0 0 1 1 1 0 LicD family ALMT PF11744.8 RUS86267.1 - 8.2 5.1 9.7 9.9 4.9 9.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter ORC_WH_C PF18137.1 RUS86267.1 - 8.4 6.5 14.6 12 6.0 14.6 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Vfa1 PF08432.10 RUS86267.1 - 9.4 6.5 30.6 14 6.0 30.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 RUS86267.1 - 9.7 4.3 15.4 12 4.1 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 RUS86269.1 - 5.5e-20 71.0 0.1 1.6e-12 47.0 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS86269.1 - 0.01 15.4 0.1 0.031 13.9 0.1 1.7 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS86269.1 - 0.019 15.1 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif bVLRF1 PF18826.1 RUS86269.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 bacteroidetes VLRF1 release factor RRM_1 PF00076.22 RUS86270.1 - 3.4e-47 158.1 5.1 3.4e-13 49.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS86270.1 - 5.1e-06 26.2 0.0 0.00058 19.7 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 RUS86270.1 - 0.0019 17.8 0.0 0.023 14.3 0.0 2.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS86270.1 - 0.018 15.1 0.2 37 4.5 0.0 4.3 4 1 0 4 4 4 0 RNA recognition motif TRAP_alpha PF03896.16 RUS86270.1 - 0.019 14.2 7.6 0.042 13.1 7.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PHM7_cyt PF14703.6 RUS86270.1 - 0.17 12.1 10.9 14 5.9 0.0 4.6 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter V_ATPase_I PF01496.19 RUS86270.1 - 0.34 8.8 3.0 0.55 8.1 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_3 PF08777.11 RUS86270.1 - 0.93 9.6 13.6 1.3 9.1 0.0 4.7 5 0 0 5 5 5 0 RNA binding motif RNA_polI_A34 PF08208.11 RUS86270.1 - 1.7 8.7 18.4 0.022 14.9 5.1 3.0 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 SpoIIIAH PF12685.7 RUS86270.1 - 4.8 7.0 16.9 1.2 9.0 6.7 3.1 3 0 0 3 3 3 0 SpoIIIAH-like protein Colicin_V PF02674.16 RUS86271.1 - 0.0009 19.2 2.1 0.0014 18.6 2.1 1.2 1 0 0 1 1 1 1 Colicin V production protein DUF2721 PF11026.8 RUS86271.1 - 0.0067 16.3 0.5 0.0067 16.3 0.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) DUF872 PF05915.12 RUS86271.1 - 0.036 14.2 0.1 0.036 14.2 0.1 2.7 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.6 RUS86271.1 - 0.5 10.5 2.8 0.91 9.7 2.8 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF202 PF02656.15 RUS86271.1 - 1.1 9.8 3.0 2.3 8.7 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) EIF4E-T PF10477.9 RUS86271.1 - 2.5 6.8 44.7 0.035 12.9 5.9 2.1 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E 7tm_1 PF00001.21 RUS86274.1 - 1.1e-11 44.5 12.9 1.8e-11 43.9 12.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS86274.1 - 1.2e-05 25.1 13.4 1.2e-05 25.1 13.4 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TMEM154 PF15102.6 RUS86274.1 - 0.22 11.4 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Cpta_toxin PF07254.12 RUS86274.1 - 1.3 9.0 5.7 2 8.4 0.8 2.7 1 1 1 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system ShK PF01549.24 RUS86276.1 - 0.0071 16.9 4.0 0.023 15.2 4.0 2.0 1 0 0 1 1 1 1 ShK domain-like PTR2 PF00854.21 RUS86277.1 - 7.2e-33 114.0 0.4 6.5e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 POT family MFS_1 PF07690.16 RUS86277.1 - 0.00083 18.4 20.2 0.0069 15.4 1.0 3.6 4 1 0 4 4 4 2 Major Facilitator Superfamily DUF1127 PF06568.11 RUS86277.1 - 5.7 6.7 6.5 11 5.8 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) OLF PF02191.16 RUS86278.1 - 1e-37 130.0 0.2 2e-30 106.1 0.1 3.2 2 1 1 3 3 3 3 Olfactomedin-like domain DUF1664 PF07889.12 RUS86278.1 - 0.78 9.8 5.1 0.84 9.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 RUS86279.1 - 6e-56 189.7 0.2 1.4e-55 188.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86279.1 - 1.6e-32 112.8 0.0 1.6e-32 112.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS86279.1 - 0.0026 17.1 0.0 0.083 12.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RUS86279.1 - 0.0055 15.5 0.3 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RUS86279.1 - 0.0072 16.3 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS86279.1 - 0.0074 15.3 0.0 0.046 12.7 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RUS86279.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 RUS86279.1 - 0.092 12.1 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YppG PF14179.6 RUS86279.1 - 0.1 13.3 1.7 0.26 12.0 1.7 1.6 1 0 0 1 1 1 0 YppG-like protein FTA2 PF13095.6 RUS86279.1 - 0.15 11.7 0.0 0.62 9.7 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 U1snRNP70_N PF12220.8 RUS86279.1 - 2.3 8.9 7.6 0.21 12.3 2.4 1.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HEAT PF02985.22 RUS86280.1 - 6.1e-16 57.2 1.5 0.0028 17.8 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 RUS86280.1 - 3.4e-14 53.0 2.4 1.1e-05 25.8 0.0 3.3 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 RUS86280.1 - 8.4e-08 32.6 5.5 0.00034 21.0 0.1 4.3 3 1 1 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 RUS86280.1 - 4.6e-07 30.0 0.3 0.0068 16.5 0.0 2.2 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RUS86280.1 - 1.5e-06 28.0 11.5 0.41 10.8 0.2 5.4 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 RUS86280.1 - 2.8e-05 22.9 0.0 3.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Surfac_D-trimer PF09006.11 RUS86280.1 - 0.0092 15.9 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 Lung surfactant protein D coiled-coil trimerisation TAF6_C PF07571.13 RUS86280.1 - 0.026 14.8 0.1 0.22 11.9 0.2 2.1 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain DUF4042 PF13251.6 RUS86280.1 - 0.074 12.7 1.0 15 5.3 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) CLASP_N PF12348.8 RUS86280.1 - 0.14 11.7 0.0 0.96 9.0 0.0 2.0 2 0 0 2 2 2 0 CLASP N terminal CENP-S PF15630.6 RUS86281.1 - 1.6e-23 82.9 1.1 1.6e-23 82.8 0.2 1.4 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 RUS86281.1 - 3.7e-07 30.2 0.5 4.7e-07 29.9 0.5 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 RUS86281.1 - 0.053 13.5 0.0 0.094 12.7 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated Ras PF00071.22 RUS86282.1 - 3.4e-53 179.6 0.0 3.8e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86282.1 - 1.7e-19 70.2 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS86282.1 - 3.2e-09 36.5 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS86282.1 - 0.018 14.5 0.0 0.1 12.1 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 RUS86282.1 - 0.064 13.5 0.1 0.098 12.9 0.1 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DFF-C PF09033.10 RUS86283.1 - 3.4e-17 62.8 0.0 4.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.15 RUS86283.1 - 2.5e-14 53.0 0.0 4.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 CIDE-N domain RNase_T PF00929.24 RUS86284.1 - 0.0051 17.4 0.0 0.0074 16.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF4757 PF15949.5 RUS86285.1 - 8.2e-09 36.2 5.4 8.2e-09 36.2 5.4 8.8 6 2 2 9 9 9 1 Domain of unknown function (DUF4757) PDZ PF00595.24 RUS86285.1 - 4.2e-07 30.2 0.0 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS86285.1 - 0.058 13.2 0.5 0.13 12.1 0.5 1.7 1 0 0 1 1 1 0 PDZ domain I-set PF07679.16 RUS86287.1 - 8.1e-24 83.5 0.0 7.3e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS86287.1 - 9.9e-21 74.1 0.0 4.1e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS86287.1 - 2.4e-20 72.7 0.0 4.3e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS86287.1 - 4.3e-19 68.5 0.0 4.4e-11 42.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS86287.1 - 2.7e-10 40.4 0.0 0.0036 17.5 0.0 4.5 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS86287.1 - 0.0017 17.9 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 RUS86287.1 - 0.0022 18.0 0.0 0.22 11.6 0.0 3.0 3 1 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 RUS86287.1 - 0.085 12.9 0.0 0.45 10.6 0.0 2.2 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain TMEM52 PF14979.6 RUS86287.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane 52 DUF5549 PF17703.1 RUS86287.1 - 1.4 8.5 5.5 11 5.6 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5549) SUFU_C PF12470.8 RUS86288.1 - 2.4e-70 236.7 0.0 3.6e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 RUS86288.1 - 3.6e-47 160.6 0.0 6.8e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) DUF3304 PF11745.8 RUS86289.1 - 0.0011 19.3 40.1 4.7 7.7 0.2 9.6 1 1 11 12 12 12 7 Protein of unknown function (DUF3304) COMPASS-Shg1 PF05205.12 RUS86290.1 - 6.3e-20 71.8 0.2 6.3e-20 71.8 0.2 3.0 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Mito_carr PF00153.27 RUS86291.1 - 3.2e-65 216.1 0.5 2.8e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RUS86291.1 - 0.012 14.8 0.3 0.15 11.2 0.1 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RRM_1 PF00076.22 RUS86292.1 - 8.7e-54 179.2 0.0 1.6e-19 69.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS86292.1 - 2.5e-11 43.3 0.0 0.0096 15.5 0.0 3.4 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS86292.1 - 5e-08 32.9 0.1 0.05 13.7 0.0 4.6 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 RUS86292.1 - 2.4e-06 27.3 0.0 0.023 14.6 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RUS86292.1 - 4.4e-06 27.0 0.7 1.2 9.3 0.0 3.5 3 1 1 4 4 4 3 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 RUS86292.1 - 2e-05 24.5 0.1 0.0025 17.8 0.0 2.6 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 RUS86292.1 - 0.00017 21.6 0.3 0.051 13.6 0.1 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 RUS86292.1 - 0.00087 19.1 0.1 0.2 11.4 0.1 3.1 2 1 2 4 4 4 1 Rrp7 RRM-like N-terminal domain RL PF17797.1 RUS86292.1 - 0.0076 16.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 RL domain zf-CCCH_7 PF18586.1 RUS86292.1 - 0.014 15.7 0.1 0.03 14.6 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4523 PF15023.6 RUS86292.1 - 0.033 14.0 0.2 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) DbpA PF03880.15 RUS86292.1 - 0.12 12.4 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain RVT_1 PF00078.27 RUS86294.1 - 6.5e-44 150.1 0.7 1.3e-43 149.1 0.5 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HECT PF00632.25 RUS86295.1 - 2.9e-85 286.4 0.0 4.1e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.11 RUS86295.1 - 0.012 15.5 0.5 0.029 14.3 0.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ADK_lid PF05191.14 RUS86295.1 - 0.12 12.4 0.7 0.64 10.0 0.3 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn_Tnp_IS91 PF14319.6 RUS86295.1 - 0.15 12.1 0.4 0.39 10.8 0.4 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain Cys_rich_CPCC PF14206.6 RUS86295.1 - 0.16 11.8 0.6 0.34 10.8 0.6 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC IBR PF01485.21 RUS86295.1 - 0.24 11.7 1.1 0.58 10.4 1.1 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Auto_anti-p27 PF06677.12 RUS86295.1 - 0.45 10.7 3.8 0.92 9.7 3.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SMAP PF15477.6 RUS86296.1 - 6.7e-11 43.0 1.2 6.7e-11 43.0 1.2 3.5 2 1 0 2 2 2 1 Small acidic protein family Nucleoporin_FG PF13634.6 RUS86296.1 - 3.6 8.5 9.6 0.74 10.7 3.7 2.9 2 1 0 2 2 2 0 Nucleoporin FG repeat region IKI3 PF04762.12 RUS86297.1 - 5.6e-281 934.8 0.0 6.8e-281 934.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 RUS86297.1 - 6.5e-08 32.8 0.2 1.7 9.0 0.0 6.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS86297.1 - 0.059 14.3 0.5 8 7.5 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-LSD1 PF06943.12 RUS86297.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 LSD1 zinc finger Ig_3 PF13927.6 RUS86298.1 - 3.5e-17 62.7 0.0 6.3e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS86298.1 - 2.3e-15 56.5 0.0 8e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS86298.1 - 3.6e-13 49.4 0.0 2.5e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RUS86298.1 - 7.5e-10 39.0 0.0 0.002 18.3 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS86298.1 - 6.6e-08 32.8 0.0 0.0001 22.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS86298.1 - 7.1e-05 22.3 0.0 0.046 13.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS86298.1 - 0.001 19.1 0.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS86298.1 - 0.0017 18.6 0.0 4.8 7.5 0.0 3.2 2 1 1 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS86298.1 - 0.0068 16.8 0.2 0.35 11.3 0.1 2.6 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain GEMIN8 PF15348.6 RUS86299.1 - 0.0092 16.3 2.2 2.2 8.5 0.1 2.3 2 0 0 2 2 2 2 Gemini of Cajal bodies-associated protein 8 SHS2_FTSA PF02491.20 RUS86299.1 - 0.085 13.3 0.5 14 6.1 0.1 2.2 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA GATA PF00320.27 RUS86299.1 - 0.93 9.2 6.4 10 5.8 0.7 2.6 2 0 0 2 2 2 0 GATA zinc finger hemP PF10636.9 RUS86299.1 - 0.96 9.3 2.3 34 4.3 0.2 2.5 2 0 0 2 2 2 0 Hemin uptake protein hemP Chorein_N PF12624.7 RUS86300.1 - 0.016 15.3 1.7 6.6 6.9 0.1 3.0 1 1 2 3 3 3 0 N-terminal region of Chorein or VPS13 Glyoxalase_3 PF13468.6 RUS86300.1 - 0.55 10.3 4.6 48 4.0 0.2 4.2 1 1 0 4 4 4 0 Glyoxalase-like domain GP63 PF17471.2 RUS86301.1 - 0.11 12.7 0.6 14 5.9 0.1 2.9 1 1 1 2 2 2 0 Gene product 63 Med27 PF11571.8 RUS86302.1 - 0.16 12.3 5.1 3.1 8.2 1.4 2.6 2 0 0 2 2 2 0 Mediator complex subunit 27 TTL PF03133.15 RUS86303.1 - 8.9e-101 336.9 0.2 1.4e-100 336.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RUS86303.1 - 5.4e-05 22.6 0.3 0.0036 16.6 0.0 2.8 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RUS86303.1 - 0.0027 17.0 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp gp12-short_mid PF09089.10 RUS86304.1 - 0.045 13.9 1.1 0.071 13.3 1.1 1.3 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain Sulfotransfer_1 PF00685.27 RUS86305.1 - 2.4e-14 53.5 0.0 1.8e-13 50.6 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS86305.1 - 5e-08 33.6 1.8 1.1e-05 25.9 1.8 2.8 1 1 0 1 1 1 1 Sulfotransferase family Spindle_Spc25 PF08234.12 RUS86306.1 - 7.2e-19 67.8 0.1 1.5e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF3037 PF11236.8 RUS86306.1 - 0.073 13.5 1.5 2.3 8.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) TMPIT PF07851.13 RUS86306.1 - 0.65 9.2 5.7 0.89 8.7 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 RUS86306.1 - 1.5 8.2 14.3 1.9 7.9 14.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 RUS86306.1 - 2.9 7.2 6.8 3.6 6.8 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 RUS86306.1 - 7.1 6.7 18.1 14 5.7 18.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 RUS86307.1 - 1.2e-19 70.3 8.7 3e-06 27.8 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86307.1 - 7.8e-05 22.9 0.0 10 6.5 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LMF1 PF06762.14 RUS86308.1 - 3e-141 471.5 12.3 3.7e-71 240.5 5.2 2.2 1 1 1 2 2 2 2 Lipase maturation factor APH PF01636.23 RUS86309.1 - 2.3e-13 50.6 0.0 3.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RUS86309.1 - 1.8e-07 30.8 0.2 5.9e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 RUS86309.1 - 0.00013 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 RUS86309.1 - 0.00093 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 RUS86309.1 - 0.056 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kelch_1 PF01344.25 RUS86310.1 - 1.1e-54 181.8 7.7 8.5e-16 57.3 0.0 4.4 4 0 0 4 4 4 4 Kelch motif BACK PF07707.15 RUS86310.1 - 4.6e-31 107.0 0.4 9.6e-31 105.9 0.4 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 RUS86310.1 - 7e-30 103.5 0.0 2.2e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 RUS86310.1 - 2.3e-27 94.3 5.3 4e-09 36.4 0.0 4.6 2 1 2 4 4 4 4 Kelch motif Kelch_2 PF07646.15 RUS86310.1 - 4.6e-20 70.7 2.0 1.6e-06 27.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 RUS86310.1 - 3e-16 59.2 2.8 0.011 15.7 0.1 4.3 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS86310.1 - 1.5e-14 53.9 3.8 0.0023 18.1 0.1 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS86310.1 - 1.2e-06 28.3 6.1 0.1 12.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif dNK PF01712.19 RUS86311.1 - 0.0053 16.6 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase TsaE PF02367.17 RUS86311.1 - 0.009 16.0 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RAWUL PF16207.5 RUS86313.1 - 1.5e-12 48.0 0.5 3.6e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 RUS86313.1 - 2.1e-12 46.6 8.6 2.1e-12 46.6 8.6 2.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS86313.1 - 1.4e-09 37.6 10.8 1.4e-09 37.6 10.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS86313.1 - 8.5e-07 29.2 8.4 8.5e-07 29.2 8.4 2.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS86313.1 - 5.2e-06 26.2 8.5 5.2e-06 26.2 8.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS86313.1 - 0.00013 21.9 10.2 0.00013 21.9 10.2 3.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS86313.1 - 0.00015 21.7 9.0 0.00015 21.7 9.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS86313.1 - 0.00034 20.7 10.2 0.00034 20.7 10.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RUS86313.1 - 0.00035 20.8 6.9 0.00035 20.8 6.9 2.9 3 2 1 4 4 3 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RUS86313.1 - 0.0034 17.5 4.6 0.0034 17.5 4.6 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 DUF3337 PF11816.8 RUS86313.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-Nse PF11789.8 RUS86313.1 - 0.021 14.7 5.6 0.042 13.7 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 RUS86313.1 - 0.06 13.4 1.8 0.18 11.9 1.8 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 RUS86313.1 - 0.095 12.6 5.5 0.3 11.0 5.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS86313.1 - 0.1 12.5 10.1 0.043 13.7 6.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS86313.1 - 0.84 9.5 12.1 1.9 8.4 7.7 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 RUS86313.1 - 1.5 8.9 12.7 1.6 8.8 5.8 2.6 3 0 0 3 3 2 0 Double zinc ribbon DUF1272 PF06906.11 RUS86313.1 - 2.9 8.1 10.2 0.71 10.0 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc_ribbon_15 PF17032.5 RUS86313.1 - 3.1 8.6 16.5 5.6 7.8 6.5 2.8 3 0 0 3 3 3 0 zinc-ribbon family RAWUL PF16207.5 RUS86314.1 - 3.9e-11 43.5 0.1 3.9e-11 43.5 0.1 2.3 3 0 0 3 3 3 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 RUS86314.1 - 2e-08 33.9 13.3 2e-08 33.9 13.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS86314.1 - 7.1e-07 29.0 14.1 7.1e-07 29.0 14.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS86314.1 - 0.00033 20.9 12.4 0.00033 20.9 12.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS86314.1 - 0.0011 18.8 12.2 0.0011 18.8 12.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS86314.1 - 0.0013 18.6 14.5 0.0013 18.6 14.5 2.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS86314.1 - 0.0032 17.5 8.3 0.0032 17.5 8.3 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS86314.1 - 0.063 13.6 9.5 0.13 12.5 9.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 RUS86314.1 - 0.078 12.8 8.3 0.15 11.9 8.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 RUS86314.1 - 0.1 12.8 13.6 0.22 11.7 13.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS86314.1 - 0.59 10.0 14.8 1.8 8.5 14.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pkinase_Tyr PF07714.17 RUS86315.1 - 3.1e-83 279.0 0.0 3.8e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS86315.1 - 1.3e-44 152.5 0.0 1.8e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS86315.1 - 2e-22 79.1 0.2 4.2e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 RUS86315.1 - 8.6e-11 41.3 0.0 2.4e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS86315.1 - 3e-08 33.4 0.0 7.3e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS86315.1 - 1.7e-06 27.6 0.0 6.7e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 RUS86315.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RUS86315.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 RUS86315.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like GalP_UDP_transf PF01087.22 RUS86316.1 - 1.1e-64 218.3 0.0 1.7e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 RUS86316.1 - 4.9e-57 192.3 2.3 7.2e-57 191.7 0.8 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 RUS86316.1 - 0.071 13.9 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 HIT domain Gp-FAR-1 PF05823.12 RUS86316.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) C2 PF00168.30 RUS86317.1 - 1.1e-09 38.5 0.1 2.9e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain TIG PF01833.24 RUS86317.1 - 0.00023 21.2 0.1 0.00053 20.0 0.1 1.7 1 0 0 1 1 1 1 IPT/TIG domain RBD-FIP PF09457.10 RUS86317.1 - 0.0077 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 FIP domain DUF1199 PF06712.11 RUS86317.1 - 0.08 13.0 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) DivIC PF04977.15 RUS86317.1 - 0.91 9.3 3.2 1.5 8.7 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Tho2 PF11262.8 RUS86317.1 - 4.2 6.5 5.4 0.77 8.9 0.8 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TIG PF01833.24 RUS86318.1 - 2.3e-28 98.1 14.7 9.7e-14 51.2 0.6 5.1 5 0 0 5 5 5 3 IPT/TIG domain PA14 PF07691.12 RUS86318.1 - 6.9e-07 29.2 1.1 6.6e-06 26.0 0.1 2.7 3 0 0 3 3 3 1 PA14 domain GLEYA PF10528.9 RUS86318.1 - 0.0015 18.9 0.6 0.03 14.8 0.0 3.2 3 0 0 3 3 3 1 GLEYA domain RHD_dimer PF16179.5 RUS86318.1 - 0.0078 16.2 0.0 2.8 8.0 0.0 2.8 2 0 0 2 2 2 2 Rel homology dimerisation domain Y_Y_Y PF07495.13 RUS86318.1 - 0.013 15.5 0.0 8.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Y_Y_Y domain Filamin PF00630.19 RUS86318.1 - 0.13 13.1 1.2 2.4 9.0 0.0 3.5 3 1 0 3 3 3 0 Filamin/ABP280 repeat Dickkopf_N PF04706.12 RUS86319.1 - 7.6 7.1 58.9 4.5 7.8 2.5 6.0 1 1 6 7 7 7 0 Dickkopf N-terminal cysteine-rich region Amelogenin PF02948.15 RUS86320.1 - 0.15 12.7 10.8 16 6.1 10.8 2.3 1 1 0 1 1 1 0 Amelogenin zf-C2H2 PF00096.26 RUS86321.1 - 6.8e-07 29.4 19.7 0.015 15.7 0.9 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86321.1 - 1.6e-06 28.5 29.4 0.00069 20.3 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 RUS86321.1 - 2e-05 24.8 3.6 2e-05 24.8 3.6 2.6 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RUS86321.1 - 0.00013 22.2 13.7 0.26 11.6 3.3 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS86321.1 - 0.0014 18.9 14.1 0.55 10.6 0.1 3.8 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) PHD_4 PF16866.5 RUS86321.1 - 0.035 14.2 3.1 0.073 13.2 0.3 2.8 2 0 0 2 2 2 0 PHD-finger zf-met PF12874.7 RUS86321.1 - 3.2 8.3 17.0 0.29 11.6 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS86322.1 - 1.1e-11 44.5 15.0 0.00058 20.5 0.4 4.0 4 0 0 4 4 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 RUS86322.1 - 8.4e-11 42.0 4.1 8.2e-07 29.2 0.2 2.5 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS86322.1 - 1.1e-07 32.0 12.9 0.0045 17.4 0.0 4.9 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86322.1 - 6.2e-07 29.5 1.8 0.0034 17.7 0.4 4.3 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS86322.1 - 0.00092 19.4 2.4 0.56 10.6 0.0 3.9 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 RUS86322.1 - 0.0014 18.7 4.6 0.075 13.2 0.5 3.3 2 1 1 3 3 3 2 Zinc ribbon domain DUF1360 PF07098.11 RUS86322.1 - 0.0059 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1360) DZR PF12773.7 RUS86322.1 - 0.0068 16.4 2.7 2.4 8.2 0.4 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 RUS86322.1 - 0.013 15.5 6.6 3.9 7.6 0.0 4.1 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger Elf1 PF05129.13 RUS86322.1 - 0.017 15.2 3.5 1.8 8.7 0.1 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 RUS86322.1 - 0.022 14.6 0.4 3.5 7.5 0.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 RUS86322.1 - 0.023 15.0 5.3 0.29 11.5 3.7 3.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 RUS86322.1 - 0.028 14.9 3.7 0.48 10.9 0.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 RUS86322.1 - 0.029 14.1 0.4 0.029 14.1 0.4 3.1 3 1 1 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 RUS86322.1 - 0.037 13.9 0.0 0.037 13.9 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 RUS86322.1 - 0.066 13.2 0.2 0.066 13.2 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger HypA PF01155.19 RUS86322.1 - 0.1 12.6 3.1 1.8 8.6 3.3 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 RUS86322.1 - 0.11 12.7 6.8 8.6 6.6 0.0 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger Actin_micro PF17003.5 RUS86322.1 - 0.19 10.9 1.3 3.7 6.6 0.1 2.1 1 1 1 2 2 2 0 Putative actin-like family zinc_ribbon_9 PF14369.6 RUS86322.1 - 0.35 11.2 7.3 3.4 8.0 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon zf-H2C2_5 PF13909.6 RUS86322.1 - 0.42 10.4 0.1 0.42 10.4 0.1 5.1 6 0 0 6 6 5 0 C2H2-type zinc-finger domain Prim_Zn_Ribbon PF08273.12 RUS86322.1 - 0.44 10.9 0.3 0.44 10.9 0.3 3.1 4 0 0 4 4 3 0 Zinc-binding domain of primase-helicase DUF629 PF04780.12 RUS86322.1 - 0.61 8.5 1.9 10 4.5 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_3rep PF18868.1 RUS86322.1 - 0.68 10.6 3.8 6.6 7.4 1.2 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats TFIIS_C PF01096.18 RUS86322.1 - 0.95 9.4 7.1 0.48 10.3 0.3 2.8 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-CHCC PF10276.9 RUS86322.1 - 1.9 8.6 6.1 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-met PF12874.7 RUS86322.1 - 6 7.4 7.9 12 6.4 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger of C2H2 type PhnA_Zn_Ribbon PF08274.12 RUS86322.1 - 7.1 6.7 8.9 12 5.9 0.1 3.5 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.6 RUS86322.1 - 8.3 7.0 10.2 6.3 7.4 1.2 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Hydrolase_4 PF12146.8 RUS86323.1 - 2.1e-13 50.1 0.0 4e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RUS86323.1 - 3.5e-08 34.3 0.2 1e-05 26.2 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS86323.1 - 2.3e-07 30.7 0.2 0.0035 17.0 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS86323.1 - 6.5e-06 25.8 0.0 0.0003 20.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 RUS86323.1 - 0.00027 20.6 0.0 0.00053 19.6 0.0 1.4 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF818 PF05677.12 RUS86323.1 - 0.0017 17.4 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 RUS86323.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 RUS86323.1 - 0.0028 17.4 0.0 0.0058 16.3 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Asp2 PF16929.5 RUS86323.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.3 2 0 0 2 2 2 1 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 RUS86323.1 - 0.0095 15.8 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase UPF0227 PF05728.12 RUS86323.1 - 0.017 15.0 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) 7tm_1 PF00001.21 RUS86324.1 - 1.2e-08 34.6 14.4 1e-07 31.6 14.4 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3278 PF11683.8 RUS86324.1 - 1.2 9.3 4.4 0.72 9.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Mpp10 PF04006.12 RUS86325.1 - 4.3e-146 487.9 106.2 8.1e-146 487.0 106.2 1.4 1 1 0 1 1 1 1 Mpp10 protein Homeodomain PF00046.29 RUS86326.1 - 0.0013 18.5 5.7 0.0026 17.5 5.7 1.5 1 0 0 1 1 1 1 Homeodomain EGF_CA PF07645.15 RUS86328.1 - 2.5e-67 222.8 131.4 2.8e-10 40.2 6.5 9.4 9 0 0 9 9 9 9 Calcium-binding EGF domain cEGF PF12662.7 RUS86328.1 - 5.7e-49 163.6 85.0 1.9e-10 40.5 2.9 10.3 9 0 0 9 9 9 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS86328.1 - 2.8e-38 129.9 124.6 2.2e-09 37.5 6.2 9.7 6 2 2 9 9 9 9 Coagulation Factor Xa inhibitory site EGF PF00008.27 RUS86328.1 - 7.6e-23 80.5 117.0 0.00019 21.7 2.4 10.4 9 1 0 9 9 9 9 EGF-like domain EGF_3 PF12947.7 RUS86328.1 - 1.2e-15 57.4 112.8 3.1e-05 24.1 0.6 11.1 9 1 1 10 10 10 8 EGF domain hEGF PF12661.7 RUS86328.1 - 8.5e-11 42.1 107.3 0.00039 20.9 0.9 11.9 11 1 0 11 11 11 6 Human growth factor-like EGF Ig_3 PF13927.6 RUS86330.1 - 9.2e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS86330.1 - 2.7e-12 46.6 0.0 4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS86330.1 - 7.1e-11 42.3 0.0 1.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain EGF_2 PF07974.13 RUS86330.1 - 1.4e-07 31.8 65.6 0.0013 19.1 8.1 5.0 4 0 0 4 4 4 3 EGF-like domain ig PF00047.25 RUS86330.1 - 2.9e-05 24.1 0.0 5.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS86330.1 - 0.0015 18.7 0.2 0.016 15.4 0.2 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain hEGF PF12661.7 RUS86330.1 - 0.2 12.3 47.4 0.058 14.1 9.0 5.7 5 1 0 5 5 5 0 Human growth factor-like EGF zf-C2H2_4 PF13894.6 RUS86331.1 - 2.5e-23 80.7 83.4 0.0052 17.5 2.6 11.7 12 0 0 12 12 12 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS86331.1 - 1.1e-18 66.7 75.3 4.2e-06 26.9 1.5 11.4 12 0 0 12 12 11 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86331.1 - 1.7e-12 47.1 92.4 0.0057 17.0 0.2 11.7 12 0 0 12 12 12 7 Zinc finger, C2H2 type zf-met PF12874.7 RUS86331.1 - 1.2e-08 35.1 68.5 0.03 14.7 0.2 11.9 12 0 0 12 12 12 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS86331.1 - 1.6e-05 25.0 52.5 0.062 13.6 0.2 10.1 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS86331.1 - 0.00078 19.7 55.1 1.9 8.9 0.2 8.7 1 1 8 9 9 9 3 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 RUS86331.1 - 0.032 15.0 38.0 0.72 10.6 5.2 5.9 1 1 3 5 5 5 0 zinc-ribbon family zf-C2H2_6 PF13912.6 RUS86331.1 - 0.054 13.5 0.7 0.054 13.5 0.7 11.7 11 1 0 11 11 11 0 C2H2-type zinc finger zf-trcl PF13451.6 RUS86331.1 - 0.062 13.2 0.5 0.062 13.2 0.5 6.7 8 0 0 8 8 8 0 Probable zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 RUS86331.1 - 0.11 12.4 0.2 0.11 12.4 0.2 6.3 8 1 0 8 8 8 0 PhnA Zinc-Ribbon GAGA PF09237.11 RUS86331.1 - 1.5 8.7 0.0 1.5 8.7 0.0 6.4 3 2 4 7 7 7 0 GAGA factor zf_UBZ PF18439.1 RUS86331.1 - 1.7 8.3 36.6 1.2 8.8 0.1 8.2 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 RUS86331.1 - 8.8 5.9 18.9 7.4 6.1 0.1 5.9 6 0 0 6 6 6 0 zinc-ribbon domain Condensation PF00668.20 RUS86334.1 - 0.15 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Condensation domain Pkinase PF00069.25 RUS86335.1 - 1.3e-13 51.0 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain COLFI PF01410.18 RUS86337.1 - 1.3e-50 171.9 0.0 1.5e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain EAV_GP5 PF15981.5 RUS86339.1 - 5.3e-07 29.9 5.1 7.7 7.0 0.1 5.3 1 1 5 7 7 7 7 Envelope glycoprotein GP 5 of equine arteritis virus DUF2711 PF10924.8 RUS86339.1 - 0.00052 19.7 1.2 0.69 9.5 0.1 3.5 1 1 5 6 6 6 5 Protein of unknown function (DUF2711) RNase_H2-Ydr279 PF09468.10 RUS86339.1 - 0.05 13.8 8.3 11 6.2 0.2 4.2 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Exo_endo_phos_2 PF14529.6 RUS86340.1 - 1.2e-14 54.2 0.1 1.2e-14 54.2 0.1 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS86340.1 - 6.7e-07 29.1 0.0 1.6e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Collagen PF01391.18 RUS86341.1 - 1.4e-63 210.5 232.4 3.4e-09 36.3 17.3 8.4 3 1 5 8 8 8 8 Collagen triple helix repeat (20 copies) Laminin_G_2 PF02210.24 RUS86342.1 - 0.19 12.3 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain ABC2_membrane PF01061.24 RUS86344.1 - 1.4e-36 125.9 23.8 2e-36 125.4 23.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RUS86344.1 - 1.2e-21 77.6 0.0 2.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 RUS86344.1 - 8.4e-09 35.0 21.5 8.4e-09 35.0 21.5 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 RUS86344.1 - 2.2e-06 27.7 0.1 0.028 14.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS86344.1 - 3.9e-06 26.5 0.4 0.0061 16.0 0.1 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.7 RUS86344.1 - 4.6e-06 26.1 5.8 4.6e-06 26.1 5.8 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 RUS86344.1 - 0.00012 22.0 0.2 0.00036 20.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 RUS86344.1 - 0.002 17.8 0.2 0.0047 16.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RUS86344.1 - 0.002 18.6 0.1 0.0041 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 RUS86344.1 - 0.23 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IgGFc_binding PF17517.2 RUS86346.1 - 2.8e-14 53.1 1.5 3.7e-14 52.7 1.5 1.1 1 0 0 1 1 1 1 IgGFc binding protein Adhesin_E PF16747.5 RUS86346.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Surface-adhesin protein E Lectin_C PF00059.21 RUS86347.1 - 1.7e-10 41.6 1.1 1.9e-10 41.5 1.1 1.0 1 0 0 1 1 1 1 Lectin C-type domain DUF4807 PF16065.5 RUS86349.1 - 6e-39 132.6 1.0 9.4e-39 132.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) AAA_33 PF13671.6 RUS86352.1 - 3.2e-28 98.7 0.7 3.4e-28 98.6 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RUS86352.1 - 0.00067 20.2 0.1 0.0012 19.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain GRP PF07172.11 RUS86352.1 - 0.0069 17.0 18.8 0.0069 17.0 18.8 3.3 2 1 1 3 3 3 1 Glycine rich protein family PhoD PF09423.10 RUS86352.1 - 0.0084 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Zeta_toxin PF06414.12 RUS86352.1 - 0.018 14.3 0.1 0.065 12.5 0.1 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 RUS86352.1 - 0.043 14.2 0.3 0.1 13.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 RUS86352.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FHA PF00498.26 RUS86353.1 - 1.4e-14 54.2 1.6 3.1e-14 53.0 0.0 2.5 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 RUS86353.1 - 4.4e-08 33.3 0.0 1.3e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain WD40 PF00400.32 RUS86356.1 - 1.9e-34 117.1 17.9 3.3e-06 27.7 0.1 9.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Bromodomain PF00439.25 RUS86356.1 - 9.1e-33 112.2 0.0 2.1e-17 62.9 0.0 2.6 2 0 0 2 2 2 2 Bromodomain ANAPC4_WD40 PF12894.7 RUS86356.1 - 2.6e-09 37.3 0.7 0.0017 18.6 0.1 5.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Auxin_resp PF06507.13 RUS86356.1 - 0.0042 17.3 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 Auxin response factor Ge1_WD40 PF16529.5 RUS86356.1 - 0.0099 14.9 1.0 17 4.2 0.0 4.3 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PHD_2 PF13831.6 RUS86357.1 - 0.00085 18.8 2.1 0.0017 17.9 2.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS86357.1 - 0.0017 18.2 1.8 0.0033 17.3 1.8 1.5 1 0 0 1 1 1 1 PHD-finger LSM_int_assoc PF16605.5 RUS86357.1 - 0.084 13.0 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 LSM-interacting associated unstructured Prenyltransf PF01255.19 RUS86358.1 - 7.3e-77 257.9 0.9 7.7e-77 257.8 0.1 1.4 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase UQ_con PF00179.26 RUS86359.1 - 1.4e-17 63.6 0.0 3.5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF678 PF05077.12 RUS86359.1 - 0.03 14.4 0.8 3.3 7.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Tmemb_161AB PF10268.9 RUS86360.1 - 1.1e-171 571.7 11.1 1.3e-171 571.4 11.1 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB SIMPL PF04402.14 RUS86361.1 - 2.3e-09 38.0 0.0 3.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Ist1 PF03398.14 RUS86362.1 - 8.8e-65 217.6 2.8 1.1e-64 217.3 2.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway MutS_II PF05188.17 RUS86362.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 MutS domain II Biopterin_H PF00351.21 RUS86363.1 - 8.5e-177 587.1 0.0 1.1e-176 586.8 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 RUS86363.1 - 2.2e-08 33.7 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 RUS86363.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain Pkinase PF00069.25 RUS86364.1 - 1.9e-46 158.6 0.0 2.6e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86364.1 - 6.9e-23 81.2 0.0 8.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS86364.1 - 1.6e-05 25.0 0.3 4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RUS86364.1 - 0.00016 20.6 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS86364.1 - 0.00062 19.2 0.0 0.0015 17.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 RUS86364.1 - 0.001 18.6 0.4 0.0041 16.7 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 RUS86364.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RUS86364.1 - 0.01 15.4 0.2 0.018 14.6 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 RUS86364.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SpoOE-like PF09388.10 RUS86364.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein DUF1679 PF07914.11 RUS86364.1 - 0.041 12.7 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Seadorna_VP7 PF07387.11 RUS86364.1 - 0.19 10.8 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PCNP PF15473.6 RUS86365.1 - 5.6e-38 131.1 10.5 1.3e-37 129.9 10.5 1.6 1 1 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family DUF4794 PF16042.5 RUS86365.1 - 0.2 12.6 3.3 0.2 12.6 0.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4794) Peptidase_C78 PF07910.13 RUS86366.1 - 2.6e-59 200.3 0.0 4.7e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 zf-C2H2_4 PF13894.6 RUS86366.1 - 2.2e-06 28.0 18.9 0.38 11.7 0.5 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS86366.1 - 3.1e-06 27.3 0.5 0.061 13.6 0.9 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS86366.1 - 1.2e-05 25.5 20.4 0.57 10.5 0.2 4.5 3 1 1 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 RUS86366.1 - 0.00046 20.5 12.7 0.16 12.5 0.0 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-met PF12874.7 RUS86366.1 - 0.0024 18.2 10.5 0.0097 16.3 0.7 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 RUS86366.1 - 0.0062 16.4 15.5 0.33 10.8 0.1 4.4 4 0 0 4 4 4 2 C2H2 type zinc-finger (1 copy) Peptidase_C54 PF03416.19 RUS86366.1 - 0.014 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C54 PhnA_Zn_Ribbon PF08274.12 RUS86366.1 - 0.3 11.1 0.0 0.3 11.1 0.0 3.5 4 0 0 4 4 4 0 PhnA Zinc-Ribbon OrsD PF12013.8 RUS86366.1 - 0.74 10.3 5.6 22 5.6 0.0 3.9 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Rad50_zn_hook PF04423.14 RUS86366.1 - 1.2 9.0 6.1 24 4.9 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif SASRP1 PF15160.6 RUS86367.1 - 5.1e-19 68.9 0.1 7e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated serine-rich protein 1 Ank PF00023.30 RUS86368.1 - 0.00071 19.9 6.7 0.88 10.1 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 RUS86368.1 - 0.0011 19.5 0.1 0.47 11.1 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86368.1 - 0.077 13.6 0.3 2.5 8.8 0.0 3.2 3 1 0 3 3 3 0 Ankyrin repeats (many copies) SpoIIIAH PF12685.7 RUS86369.1 - 0.52 10.1 10.8 0.97 9.2 10.8 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Sporozoite_P67 PF05642.11 RUS86369.1 - 0.65 8.0 0.0 0.65 8.0 0.0 3.2 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Spc7 PF08317.11 RUS86370.1 - 0.022 13.6 21.5 0.36 9.7 7.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 RUS86370.1 - 0.12 11.9 16.0 0.085 12.4 2.6 2.3 2 0 0 2 2 2 0 TMCO5 family KASH_CCD PF14662.6 RUS86370.1 - 0.26 11.1 24.0 1.1 9.0 11.1 3.0 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 RUS86370.1 - 0.62 10.7 16.9 0.94 10.1 0.7 3.9 2 2 1 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 RUS86370.1 - 1.5 9.3 30.2 4 8.0 2.1 4.7 3 1 1 4 4 4 0 Cell division protein ZapB DUF812 PF05667.11 RUS86370.1 - 1.8 7.3 15.6 0.92 8.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF812) TSC22 PF01166.18 RUS86370.1 - 2.6 8.4 21.6 0.36 11.2 0.4 5.0 4 1 1 5 5 5 0 TSC-22/dip/bun family DUF4201 PF13870.6 RUS86370.1 - 3.7 7.2 20.1 0.18 11.6 4.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.15 RUS86370.1 - 4.8 7.0 18.6 6.4 6.6 0.2 4.3 3 1 1 4 4 4 0 Septum formation initiator SlyX PF04102.12 RUS86370.1 - 5.1 7.8 14.4 9 7.0 3.0 4.0 3 1 1 4 4 4 0 SlyX Flu_NS2 PF00601.19 RUS86370.1 - 6 7.2 6.5 26 5.2 0.2 3.2 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) DENN PF02141.21 RUS86371.1 - 2.7e-57 193.8 2.7 5.5e-57 192.7 2.7 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 RUS86371.1 - 2.1e-18 66.8 0.0 7.7e-18 65.0 0.0 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 RUS86371.1 - 7.1e-13 48.3 9.5 1.7e-12 47.1 9.5 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 RUS86371.1 - 5.8e-06 26.4 0.0 2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 RUS86371.1 - 0.00012 22.0 0.1 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 RUS86371.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ORMDL PF04061.14 RUS86373.1 - 2.6e-50 169.7 4.9 3e-50 169.6 4.9 1.0 1 0 0 1 1 1 1 ORMDL family DNA_mis_repair PF01119.19 RUS86374.1 - 6.6e-17 61.3 0.1 1.3e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RUS86374.1 - 2.4e-12 46.8 0.2 3.9e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS86374.1 - 8.8e-07 29.4 0.2 1.8e-06 28.4 0.2 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OAS1_C PF10421.9 RUS86374.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus PXA PF02194.15 RUS86375.1 - 3e-50 170.7 2.2 3e-50 170.7 2.2 2.9 3 1 0 3 3 3 1 PXA domain Nexin_C PF08628.12 RUS86375.1 - 5.1e-30 104.3 0.3 1.2e-27 96.7 0.0 3.6 2 1 1 3 3 3 1 Sorting nexin C terminal PX PF00787.24 RUS86375.1 - 1.2e-21 76.8 0.2 4.9e-21 74.8 0.2 2.1 1 0 0 1 1 1 1 PX domain RGS PF00615.19 RUS86375.1 - 8.3e-18 64.8 2.4 3.9e-17 62.6 2.4 2.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain CM_2 PF01817.21 RUS86375.1 - 0.034 14.5 1.2 35 4.8 0.0 4.4 4 2 0 4 4 4 0 Chorismate mutase type II Glucos_trans_II PF14264.6 RUS86375.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF3900 PF13039.6 RUS86375.1 - 0.24 11.3 4.4 0.41 10.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3900) EF-hand_1 PF00036.32 RUS86376.1 - 3.4e-07 29.3 1.8 0.0033 16.9 0.0 3.8 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 RUS86376.1 - 3.2e-06 26.6 0.1 0.046 13.7 0.0 3.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS86376.1 - 2.6e-05 24.6 0.6 0.019 15.4 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS86376.1 - 0.0045 16.8 1.3 2.9 7.8 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair GrlR PF16518.5 RUS86376.1 - 0.054 13.5 0.1 0.24 11.4 0.0 2.0 3 0 0 3 3 3 0 T3SS negative regulator,GrlR FRG1 PF06229.12 RUS86378.1 - 0.0048 16.6 0.2 0.0094 15.7 0.2 1.4 1 0 0 1 1 1 1 FRG1-like domain Bravo_FIGEY PF13882.6 RUS86378.1 - 1.5 10.2 12.4 22 6.5 0.5 4.2 3 1 2 5 5 5 0 Bravo-like intracellular region 7TM_GPCR_Srw PF10324.9 RUS86379.1 - 2.7e-13 49.9 1.5 2.7e-13 49.9 1.5 3.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS86379.1 - 0.005 16.2 10.6 0.019 14.3 0.3 2.6 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS86379.1 - 0.082 12.3 11.5 2 7.7 0.7 3.1 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS86379.1 - 0.69 9.2 8.9 0.032 13.6 0.8 2.5 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv Neur_chan_LBD PF02931.23 RUS86380.1 - 6.8e-35 120.5 0.1 9.3e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS86380.1 - 1.1e-18 68.2 11.9 1.4e-18 67.9 7.2 2.1 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region YqfD PF06898.11 RUS86380.1 - 0.34 9.7 1.8 0.6 8.9 1.8 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DUF5392 PF17370.2 RUS86380.1 - 0.61 10.2 5.8 0.22 11.6 2.4 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5392) YrhC PF14143.6 RUS86380.1 - 5.4 7.2 8.8 0.55 10.3 3.1 2.3 2 0 0 2 2 2 0 YrhC-like protein HSP20 PF00011.21 RUS86381.1 - 6e-33 113.0 8.3 2.5e-19 69.3 0.3 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS86381.1 - 3.6e-09 36.1 0.7 4.1e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA fn3_6 PF17766.1 RUS86381.1 - 0.045 13.9 1.1 0.48 10.6 0.1 2.8 3 0 0 3 3 3 0 Fibronectin type-III domain DUF4706 PF15797.5 RUS86381.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4706) DUF4139 PF13598.6 RUS86381.1 - 0.69 9.6 6.7 7.7 6.2 6.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4139) RHINO PF15319.6 RUS86382.1 - 5.2e-11 43.1 13.5 1.3e-08 35.2 13.5 2.3 1 1 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein ELO PF01151.18 RUS86384.1 - 5.3e-62 209.6 26.8 7.2e-62 209.1 26.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3175 PF11373.8 RUS86385.1 - 0.023 14.9 0.5 0.023 14.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3175) TMF_DNA_bd PF12329.8 RUS86385.1 - 0.037 14.0 3.4 0.078 13.0 3.4 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Med21 PF11221.8 RUS86385.1 - 0.12 12.6 2.7 0.14 12.4 2.7 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Com_YlbF PF06133.11 RUS86385.1 - 0.12 13.0 2.8 0.15 12.7 2.8 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF3450 PF11932.8 RUS86385.1 - 0.2 11.0 3.9 0.23 10.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5428 PF17493.2 RUS86385.1 - 0.89 10.0 0.1 0.89 10.0 0.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5428) Lzipper-MIP1 PF14389.6 RUS86386.1 - 0.00054 20.2 25.9 0.017 15.4 2.0 5.6 2 2 4 6 6 6 3 Leucine-zipper of ternary complex factor MIP1 Fzo_mitofusin PF04799.13 RUS86386.1 - 0.045 13.3 0.7 0.045 13.3 0.7 4.5 2 1 1 5 5 5 0 fzo-like conserved region HOOK PF05622.12 RUS86386.1 - 0.081 11.1 40.6 0.028 12.6 28.9 2.9 1 1 1 2 2 2 0 HOOK protein DUF1612 PF07756.12 RUS86386.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1612) MCC-bdg_PDZ PF10506.9 RUS86386.1 - 7.3 6.7 14.0 0.59 10.2 1.2 4.3 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SlyX PF04102.12 RUS86386.1 - 9.5 6.9 21.6 17 6.1 0.1 5.6 4 3 1 5 5 5 0 SlyX Gln-synt_C PF00120.24 RUS86387.1 - 0.0092 15.0 2.6 0.011 14.7 2.6 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain VPS11_C PF12451.8 RUS86387.1 - 0.013 15.7 1.5 0.041 14.1 0.2 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF501 PF04417.12 RUS86387.1 - 0.039 13.8 1.7 0.045 13.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Ax_dynein_light PF10211.9 RUS86387.1 - 0.04 13.9 7.0 0.028 14.4 2.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Spc7 PF08317.11 RUS86387.1 - 0.04 12.8 6.2 0.045 12.6 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mu-like_Pro PF10123.9 RUS86387.1 - 0.066 12.7 6.2 0.075 12.6 6.2 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Csm1_N PF18504.1 RUS86387.1 - 0.12 12.8 11.5 0.99 9.8 1.4 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain FAM76 PF16046.5 RUS86387.1 - 0.19 11.0 4.1 0.18 11.2 3.4 1.3 1 1 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 RUS86387.1 - 0.23 11.6 7.7 0.21 11.7 0.9 2.8 2 1 1 3 3 3 0 bZIP transcription factor LPP PF04728.13 RUS86387.1 - 0.27 11.7 5.3 0.44 11.0 0.6 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper CLZ PF16526.5 RUS86387.1 - 0.4 11.1 9.3 0.88 10.0 1.7 3.0 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 RUS86387.1 - 0.41 10.7 7.5 0.56 10.3 3.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 RUS86387.1 - 0.82 10.2 9.1 1.6 9.3 1.7 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF16 PF01519.16 RUS86387.1 - 1.4 9.5 9.3 83 3.8 9.3 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 RUS86387.1 - 2 9.1 11.5 2.1 9.0 6.6 2.6 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 RUS86387.1 - 3.1 7.6 9.3 7 6.5 0.5 2.6 1 1 2 3 3 3 0 Septum formation initiator Spc29 PF17082.5 RUS86388.1 - 0.043 13.7 2.0 0.054 13.3 1.7 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 PaaX_C PF08223.11 RUS86388.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Pepsin-I3 PF06394.13 RUS86388.1 - 0.092 13.0 1.3 0.19 11.9 1.3 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Troponin PF00992.20 RUS86389.1 - 1.2e-11 45.0 8.3 1.2e-11 45.0 8.3 2.5 2 1 0 2 2 2 1 Troponin LEP503 PF15221.6 RUS86390.1 - 1.7 9.0 24.3 7.2 7.0 0.4 5.6 1 1 2 3 3 3 0 Lens epithelial cell protein LEP503 DUF4381 PF14316.6 RUS86391.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PHD PF00628.29 RUS86392.1 - 1.1e-09 38.0 4.2 2.1e-09 37.1 4.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RUS86392.1 - 0.027 14.7 0.4 0.09 13.0 0.4 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RUS86392.1 - 0.084 13.0 0.4 0.23 11.6 0.4 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 RUS86392.1 - 0.092 13.1 2.6 0.22 11.8 2.6 1.7 1 0 0 1 1 1 0 C1 domain DUF1664 PF07889.12 RUS86392.1 - 0.14 12.2 12.5 0.1 12.7 4.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PHD_4 PF16866.5 RUS86392.1 - 0.23 11.6 4.6 0.65 10.1 4.6 1.8 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 RUS86392.1 - 0.51 10.0 4.4 0.16 11.5 0.9 1.9 2 0 0 2 2 2 0 PHD-finger Bacteriocin_IIc PF10439.9 RUS86392.1 - 0.76 9.9 4.2 1.8 8.7 4.2 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide C1_1 PF00130.22 RUS86392.1 - 0.99 9.3 6.2 0.18 11.7 2.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Syntaxin-6_N PF09177.11 RUS86392.1 - 2.6 8.7 12.0 0.6 10.7 4.2 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-RING_2 PF13639.6 RUS86392.1 - 3.8 7.9 5.7 7.6 7.0 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain FYVE PF01363.21 RUS86393.1 - 2.3e-19 69.3 11.1 2.3e-19 69.3 11.1 1.7 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 RUS86393.1 - 2.6e-09 37.5 0.5 2.7e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 RUS86393.1 - 0.0016 18.3 0.4 0.045 13.6 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 RUS86393.1 - 0.012 15.8 8.6 0.025 14.8 8.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger IQ_SEC7_PH PF16453.5 RUS86393.1 - 0.02 14.9 0.2 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 PH domain DUF2462 PF09495.10 RUS86393.1 - 0.069 13.9 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) PH_16 PF17838.1 RUS86393.1 - 0.22 11.4 0.6 0.6 10.0 0.6 1.8 1 1 0 1 1 1 0 PH domain CxC3 PF18804.1 RUS86393.1 - 1.2 9.0 9.8 3.7 7.4 3.4 2.2 1 1 1 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases WAC_Acf1_DNA_bd PF10537.9 RUS86394.1 - 8.4e-25 87.2 0.4 8.4e-25 87.2 0.4 2.6 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 RUS86394.1 - 1.3e-23 82.9 0.6 3.4e-23 81.5 0.6 1.8 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 RUS86394.1 - 2.6e-18 66.3 0.7 1.1e-15 57.8 0.1 5.1 4 2 1 5 5 4 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 RUS86394.1 - 1.6e-17 63.1 18.2 2e-11 43.6 9.2 2.8 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.6 RUS86394.1 - 3e-07 29.8 0.2 7.7e-07 28.5 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_2 PF13831.6 RUS86394.1 - 6.4e-06 25.6 2.5 0.011 15.2 0.4 3.0 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.6 RUS86394.1 - 0.0081 16.5 9.7 0.0081 16.5 9.7 2.5 2 0 0 2 2 2 1 Ring finger domain C1_1 PF00130.22 RUS86394.1 - 0.034 14.0 15.2 0.086 12.7 4.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDT PF02791.17 RUS86394.1 - 0.045 14.1 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 DDT domain Prok-RING_1 PF14446.6 RUS86394.1 - 0.21 11.6 16.2 0.26 11.2 4.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 RUS86394.1 - 0.25 11.6 22.1 0.35 11.1 10.1 2.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain Prim_Zn_Ribbon PF08273.12 RUS86394.1 - 0.92 9.8 4.1 12 6.3 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase EMP24_GP25L PF01105.24 RUS86395.1 - 3.3e-53 180.3 6.8 3.1e-26 92.4 1.8 2.1 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.6 RUS86395.1 - 1e-06 29.3 1.7 0.066 13.7 0.0 2.9 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking DUF4329 PF14220.6 RUS86395.1 - 0.041 13.9 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) YlbE PF14003.6 RUS86395.1 - 0.064 13.7 0.5 16 6.1 0.0 2.8 3 0 0 3 3 3 0 YlbE-like protein Lipocalin_4 PF13648.6 RUS86395.1 - 0.069 14.1 7.0 3.3 8.7 1.5 2.4 1 1 1 2 2 2 0 Lipocalin-like domain CS PF04969.16 RUS86396.1 - 0.00013 22.9 0.6 0.00025 22.0 0.6 1.6 1 1 0 1 1 1 1 CS domain DUF4499 PF14934.6 RUS86399.1 - 7.4e-18 64.7 0.2 9.2e-18 64.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) HLH PF00010.26 RUS86401.1 - 1.6e-07 31.2 0.1 2.7e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4924 PF16271.5 RUS86401.1 - 0.018 15.0 0.4 0.023 14.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) GlutR_dimer PF00745.20 RUS86401.1 - 0.033 14.6 3.6 3 8.4 0.2 2.2 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2161 PF09929.9 RUS86401.1 - 0.057 13.5 0.4 0.1 12.7 0.2 1.6 1 1 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Med30 PF11315.8 RUS86401.1 - 0.16 12.1 2.8 1.2 9.3 1.2 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 PurA PF04845.13 RUS86402.1 - 2.5e-96 321.2 0.1 3.1e-96 320.9 0.1 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 RUS86402.1 - 8e-05 22.8 5.7 1.8 8.7 0.0 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF3276) EFG_C PF00679.24 RUS86402.1 - 0.034 14.2 0.0 11 6.2 0.0 2.7 3 0 0 3 3 3 0 Elongation factor G C-terminus Spt20 PF12090.8 RUS86402.1 - 0.07 12.7 0.2 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Spt20 family Met_10 PF02475.16 RUS86403.1 - 2.3e-28 99.3 0.0 3.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 RUS86403.1 - 3.5e-05 24.4 0.0 8.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS86403.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Trm5_N PF18093.1 RUS86403.1 - 0.0034 17.3 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 tRNA methyltransferase 5 N-terminal domain DNA_methylase PF00145.17 RUS86403.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase RBD PF02196.15 RUS86403.1 - 0.072 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Raf-like Ras-binding domain Methyltransf_18 PF12847.7 RUS86403.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS86403.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RUS86403.1 - 0.14 12.8 0.0 0.4 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TMEM117 PF15113.6 RUS86404.1 - 1.3e-123 413.0 26.8 5.4e-73 246.3 14.8 2.0 2 0 0 2 2 2 2 TMEM117 protein family BCHF PF07284.11 RUS86404.1 - 0.54 10.3 8.9 0.27 11.3 4.3 2.4 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Peptidase_S24 PF00717.23 RUS86405.1 - 1.1e-11 44.5 0.1 1.6e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RUS86405.1 - 0.00023 20.9 0.0 0.025 14.4 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Choline_kinase PF01633.20 RUS86406.1 - 1.9e-42 145.3 0.5 5.4e-42 143.8 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 RUS86406.1 - 3.2e-08 33.8 0.0 2.7e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 RUS86406.1 - 0.059 12.7 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain SbcD_C PF12320.8 RUS86406.1 - 0.087 13.1 0.0 0.37 11.1 0.0 2.1 3 0 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain CYTH PF01928.21 RUS86407.1 - 9.7e-11 41.9 0.2 9e-08 32.3 0.3 2.0 1 1 1 2 2 2 2 CYTH domain MMR_HSR1 PF01926.23 RUS86408.1 - 4.4e-17 62.2 0.2 9.4e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 RUS86408.1 - 2.2e-14 53.8 2.5 5.6e-14 52.5 2.5 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 RUS86408.1 - 6e-12 46.1 1.4 1.6e-11 44.8 0.1 2.3 3 0 0 3 3 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.18 RUS86408.1 - 6.6e-06 25.7 0.4 1.5e-05 24.6 0.4 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 RUS86408.1 - 6.6e-05 22.6 3.8 0.014 15.0 0.4 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 RUS86408.1 - 0.00011 21.7 0.2 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS86408.1 - 0.00062 19.7 0.4 0.27 11.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 RUS86408.1 - 0.00065 19.5 0.3 0.002 17.9 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 RUS86408.1 - 0.0016 18.0 1.8 0.042 13.4 1.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RUS86408.1 - 0.0023 17.4 2.4 0.039 13.4 2.4 2.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 RUS86408.1 - 0.0044 17.0 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TniB PF05621.11 RUS86408.1 - 0.0071 15.8 0.3 0.079 12.4 0.1 2.3 2 0 0 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 RUS86408.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RUS86408.1 - 0.013 15.9 0.2 0.035 14.5 0.2 1.8 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 RUS86408.1 - 0.013 14.8 0.4 0.33 10.2 0.1 2.3 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 RUS86408.1 - 0.014 15.4 0.1 0.18 11.8 0.0 2.3 1 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 RUS86408.1 - 0.036 13.4 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 RUS86408.1 - 0.043 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 RUS86408.1 - 0.06 13.6 0.1 0.15 12.3 0.1 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 RUS86408.1 - 0.082 13.4 1.7 0.35 11.3 0.4 2.3 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 RUS86408.1 - 0.096 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 RUS86408.1 - 0.11 12.5 0.1 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 RUS86408.1 - 0.15 11.9 0.2 2.9 7.7 0.1 2.3 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LMWPc PF01451.21 RUS86409.1 - 6.5e-43 146.5 0.0 7.3e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Dimerisation2 PF16864.5 RUS86412.1 - 0.0005 20.0 20.6 18 5.4 0.4 8.5 1 1 4 5 5 5 3 Dimerisation domain Fe_dep_repress PF01325.19 RUS86412.1 - 0.59 10.4 3.6 49 4.2 0.0 4.0 2 1 1 4 4 4 0 Iron dependent repressor, N-terminal DNA binding domain SPRY PF00622.28 RUS86413.1 - 2.1e-18 66.6 0.0 3.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 RUS86413.1 - 1.9e-07 31.3 2.4 3.4e-07 30.5 2.4 1.4 1 0 0 1 1 1 1 SOCS box Peptidase_C14 PF00656.22 RUS86414.1 - 2.6e-11 44.0 0.0 2.7e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 RUS86415.1 - 1.5e-22 80.8 0.6 2.4e-22 80.1 0.3 1.4 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 RUS86415.1 - 1.3e-09 37.9 0.0 3.7e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 RUS86415.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain HELP PF03451.14 RUS86416.1 - 3.3e-22 78.1 0.0 6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 HELP motif DCX PF03607.17 RUS86416.1 - 2.5e-19 69.1 0.0 2.1e-13 50.2 0.1 2.7 2 0 0 2 2 2 2 Doublecortin WD40 PF00400.32 RUS86416.1 - 4.3e-13 49.5 23.6 4.3e-05 24.2 0.1 9.3 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86416.1 - 2.1e-09 37.5 0.0 5.6e-05 23.4 0.0 5.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS86416.1 - 0.051 12.5 0.2 2.3 7.1 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GspH PF12019.8 RUS86416.1 - 0.3 11.5 2.2 21 5.6 0.0 4.1 4 0 0 4 4 4 0 Type II transport protein GspH C1q PF00386.21 RUS86420.1 - 6.9e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 RUS86420.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family SR-25 PF10500.9 RUS86420.1 - 0.58 9.7 13.7 0.98 9.0 13.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RCC1 PF00415.18 RUS86421.1 - 3.1e-42 143.0 8.1 1.4e-14 54.4 1.4 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS86421.1 - 6.1e-28 96.0 18.1 1.8e-09 37.2 0.4 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RUS86421.1 - 1.7e-19 70.1 1.7 7.5e-19 68.0 0.6 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS86421.1 - 0.0088 16.1 1.0 0.023 14.8 0.4 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Peptidase_C25_C PF03785.14 RUS86421.1 - 0.048 13.5 3.2 0.28 11.0 0.6 2.9 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain ABC_membrane PF00664.23 RUS86422.1 - 0.098 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Proton_antipo_M PF00361.20 RUS86422.1 - 0.1 11.8 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter PDT PF00800.18 RUS86424.1 - 0.3 10.9 2.8 3.9 7.3 0.3 2.6 2 0 0 2 2 2 0 Prephenate dehydratase COBRA1 PF06209.13 RUS86426.1 - 2.8e-165 550.8 5.3 3.5e-165 550.4 5.3 1.0 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) UTP15_C PF09384.10 RUS86426.1 - 0.00071 19.3 1.9 0.6 9.8 0.0 2.7 3 0 0 3 3 3 2 UTP15 C terminal Angiomotin_C PF12240.8 RUS86427.1 - 1e-19 70.9 19.7 1e-19 70.9 19.7 4.4 6 0 0 6 6 6 3 Angiomotin C terminal DUF2783 PF10932.8 RUS86427.1 - 0.16 11.7 2.9 0.33 10.7 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) Astacin PF01400.24 RUS86428.1 - 6.1e-21 74.9 1.8 6.7e-21 74.8 1.8 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 RUS86428.1 - 0.0077 16.1 0.4 0.0096 15.8 0.4 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 RUS86428.1 - 0.021 13.8 0.4 0.025 13.5 0.3 1.3 1 1 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 RUS86428.1 - 0.11 12.4 0.9 0.14 12.1 0.9 1.4 1 1 0 1 1 1 0 Pregnancy-associated plasma protein-A NAD_binding_10 PF13460.6 RUS86429.1 - 2.2e-06 27.7 0.2 4.4e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RUS86429.1 - 7.6e-05 22.4 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 RUS86429.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 RUS86429.1 - 0.082 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_28 PF03033.20 RUS86429.1 - 0.11 12.6 0.3 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain DUF3464 PF11947.8 RUS86430.1 - 0.0056 16.4 14.6 0.0056 16.4 14.6 2.4 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 CDC45 PF02724.14 RUS86430.1 - 0.02 13.2 38.8 0.028 12.7 38.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 RUS86430.1 - 0.039 13.6 35.8 0.061 13.0 35.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CCSAP PF15748.5 RUS86430.1 - 0.054 13.7 35.3 0.066 13.4 35.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Nop53 PF07767.11 RUS86430.1 - 0.093 12.1 58.0 0.15 11.4 58.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 RUS86430.1 - 0.16 12.0 50.2 0.21 11.6 50.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SRP-alpha_N PF04086.13 RUS86430.1 - 0.45 10.4 45.5 0.51 10.2 45.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF-3c_N PF05470.12 RUS86430.1 - 0.53 8.5 21.3 0.61 8.3 21.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.17 RUS86430.1 - 0.67 8.7 26.3 0.84 8.3 26.3 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 RUS86430.1 - 1.3 7.9 27.5 1.7 7.6 27.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PCM1_C PF15717.5 RUS86430.1 - 1.7 7.3 21.9 2.3 6.8 21.9 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus LAP1C PF05609.12 RUS86430.1 - 1.8 7.6 22.1 2.2 7.3 22.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 RUS86430.1 - 3.3 4.7 17.1 3.9 4.5 17.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mlh1_C PF16413.5 RUS86430.1 - 5.8 6.2 16.4 2.9 7.2 6.9 2.2 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus CSG2 PF16965.5 RUS86430.1 - 6.9 5.5 11.9 0.21 10.5 2.3 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator SAPS PF04499.15 RUS86430.1 - 8.3 5.1 19.5 11 4.7 19.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 RUS86430.1 - 9.3 5.1 22.3 14 4.5 22.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Apt1 PF10351.9 RUS86430.1 - 9.6 4.9 24.0 12 4.6 24.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.6 RUS86430.1 - 9.7 5.8 29.3 4 7.1 11.6 2.2 2 0 0 2 2 2 0 FAM176 family Surp PF01805.20 RUS86431.1 - 8.2e-18 64.2 0.3 2.3e-17 62.7 0.3 1.9 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 RUS86431.1 - 4.6e-14 52.0 0.1 1.7e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 RUS86431.1 - 1.4e-06 28.4 5.8 1.4e-06 28.4 5.8 2.7 3 0 0 3 3 3 1 cwf21 domain CTD_bind PF04818.13 RUS86431.1 - 5.7e-06 27.1 0.6 2e-05 25.3 0.6 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 RUS86431.1 - 0.012 15.6 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 RUS86431.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Collagen PF01391.18 RUS86432.1 - 1.8e-49 165.3 140.7 1.6e-08 34.2 25.2 6.7 1 1 4 5 5 5 5 Collagen triple helix repeat (20 copies) Cuticle_3 PF11018.8 RUS86433.1 - 0.00018 21.8 0.1 0.39 10.9 0.0 3.0 1 1 2 3 3 3 3 Pupal cuticle protein C1 Collagen PF01391.18 RUS86434.1 - 8.2e-47 156.8 136.9 5.5e-10 38.9 18.0 7.0 1 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) Collagen PF01391.18 RUS86437.1 - 7.6e-46 153.7 181.4 4e-09 36.1 21.9 7.5 3 2 4 7 7 7 7 Collagen triple helix repeat (20 copies) Transposase_1 PF01359.18 RUS86437.1 - 1.4e-18 66.5 0.0 2.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Caldesmon PF02029.15 RUS86437.1 - 0.00018 20.4 24.0 0.00025 19.9 24.0 1.1 1 0 0 1 1 1 1 Caldesmon BUD22 PF09073.10 RUS86437.1 - 0.0063 15.9 38.0 0.0094 15.3 38.0 1.2 1 0 0 1 1 1 1 BUD22 DDHD PF02862.17 RUS86437.1 - 0.022 14.9 0.6 0.033 14.4 0.6 1.2 1 0 0 1 1 1 0 DDHD domain Coilin_N PF15862.5 RUS86437.1 - 0.025 14.4 5.7 0.043 13.6 5.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus ASC PF00858.24 RUS86437.1 - 0.078 11.9 0.2 0.1 11.5 0.2 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Serinc PF03348.15 RUS86437.1 - 0.13 11.1 1.6 0.19 10.6 1.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TCP PF03634.13 RUS86437.1 - 0.15 12.6 4.6 0.27 11.8 4.6 1.4 1 0 0 1 1 1 0 TCP family transcription factor RNA_pol_Rpc4 PF05132.14 RUS86437.1 - 0.15 12.5 12.8 0.42 11.0 12.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 RUS86437.1 - 0.19 10.5 10.5 0.27 10.0 10.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIP PF07454.11 RUS86437.1 - 0.33 10.4 17.4 0.49 9.8 17.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DARPP-32 PF05395.12 RUS86437.1 - 0.35 11.1 29.4 0.7 10.1 29.4 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Presenilin PF01080.17 RUS86437.1 - 0.6 8.8 15.7 0.86 8.3 15.7 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 RUS86437.1 - 0.65 10.0 3.5 4.2 7.4 2.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 RUS86437.1 - 0.67 8.3 2.2 0.9 7.9 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 RUS86437.1 - 0.75 9.2 12.7 1.2 8.5 12.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CPSF100_C PF13299.6 RUS86437.1 - 0.99 9.6 14.6 2.2 8.4 14.6 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5523 PF17661.1 RUS86437.1 - 1.6 8.4 38.3 2.6 7.6 38.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF913 PF06025.12 RUS86437.1 - 3.2 6.7 13.8 4.4 6.2 13.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 RUS86437.1 - 3.6 7.7 19.2 6.6 6.8 19.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 RUS86437.1 - 4.1 7.1 28.5 7 6.4 28.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 RUS86437.1 - 6.4 6.8 13.1 16 5.6 13.1 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein DNA_pol_phi PF04931.13 RUS86437.1 - 7.1 4.6 56.0 12 3.9 56.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi MDM1 PF15501.6 RUS86437.1 - 9.2 5.3 23.7 14 4.7 23.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SpoIIIAH PF12685.7 RUS86437.1 - 9.3 6.0 20.6 16 5.3 20.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Collagen PF01391.18 RUS86438.1 - 3e-17 62.1 50.0 6.5e-09 35.4 19.5 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) YopE PF03545.13 RUS86439.1 - 0.082 13.1 1.5 9.3 6.5 0.7 3.0 1 1 1 2 2 2 0 Yersinia virulence determinant (YopE) NOP5NT PF08156.13 RUS86439.1 - 0.2 12.1 9.8 4.8 7.7 4.1 2.6 1 1 1 2 2 2 0 NOP5NT (NUC127) domain CAMSAP_CH PF11971.8 RUS86439.1 - 0.35 10.8 3.9 12 5.8 0.4 2.8 1 1 1 2 2 2 0 CAMSAP CH domain UBA_4 PF14555.6 RUS86439.1 - 1.1 9.1 12.6 51 3.8 0.1 5.6 1 1 6 7 7 7 0 UBA-like domain NusG_II PF07009.11 RUS86440.1 - 0.43 10.8 4.8 42 4.4 0.1 3.8 4 1 0 4 4 4 0 NusG domain II 14-3-3 PF00244.20 RUS86440.1 - 3.7 7.0 5.0 5.2 6.5 0.1 2.9 2 2 2 4 4 4 0 14-3-3 protein Ig_3 PF13927.6 RUS86444.1 - 0.0079 16.8 0.1 0.79 10.4 0.0 3.5 3 1 1 4 4 4 1 Immunoglobulin domain C1-set PF07654.15 RUS86444.1 - 0.072 13.5 0.1 3.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 RUS86444.1 - 0.15 12.1 0.0 46 4.2 0.0 3.4 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Death_2 PF14786.6 RUS86445.1 - 6.7e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Tube Death domain Death PF00531.22 RUS86445.1 - 0.00038 20.6 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 Death domain Pkinase_Tyr PF07714.17 RUS86445.1 - 0.00077 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS86445.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 RUS86446.1 - 3.3e-32 111.9 0.0 4.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86446.1 - 5.7e-25 88.1 0.0 2.5e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase TLP-20 PF06088.11 RUS86446.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Kdo PF06293.14 RUS86446.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS86446.1 - 0.064 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FAM176 PF14851.6 RUS86446.1 - 0.07 12.8 0.8 0.12 12.0 0.8 1.3 1 0 0 1 1 1 0 FAM176 family BDHCT_assoc PF16204.5 RUS86446.1 - 0.11 12.1 1.9 0.16 11.6 1.9 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein PBP1_TM PF14812.6 RUS86446.1 - 0.75 10.2 9.1 1.4 9.3 9.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 RUS86446.1 - 1.3 8.7 7.8 2 8.1 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 RUS86446.1 - 1.4 9.4 12.1 2.7 8.4 12.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RUS86446.1 - 2.9 5.9 7.1 3.7 5.5 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi AMMECR1 PF01871.17 RUS86447.1 - 7.7e-30 103.7 0.0 9.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 FA_desaturase PF00487.24 RUS86448.1 - 5.2e-25 88.7 17.5 1.9e-23 83.6 18.4 2.2 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 RUS86448.1 - 1.7e-16 59.4 0.6 1.7e-16 59.4 0.6 2.3 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Metallopep PF12044.8 RUS86448.1 - 0.00028 19.6 0.5 0.00043 19.0 0.5 1.2 1 0 0 1 1 1 1 Putative peptidase family DUF2062 PF09835.9 RUS86448.1 - 0.15 11.9 2.6 0.34 10.8 2.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Caveolin PF01146.17 RUS86448.1 - 8.4 6.4 7.2 12 5.8 0.1 3.5 3 1 1 4 4 4 0 Caveolin MMR_HSR1 PF01926.23 RUS86449.1 - 3.7e-09 36.7 0.2 1.8e-07 31.2 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS86449.1 - 4.6e-06 26.3 0.0 0.0025 17.4 0.0 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RUS86449.1 - 2.4e-05 24.5 0.2 6.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Roc PF08477.13 RUS86449.1 - 0.0036 17.5 0.6 4.1 7.6 0.0 3.8 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS86449.1 - 0.004 17.1 0.1 0.019 14.9 0.1 2.3 3 0 0 3 3 3 1 RsgA GTPase Ras PF00071.22 RUS86449.1 - 0.0049 16.5 0.0 0.49 10.0 0.0 2.8 2 1 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.18 RUS86449.1 - 0.11 11.8 0.1 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family FeoB_N PF02421.18 RUS86449.1 - 0.26 10.8 0.1 0.26 10.8 0.1 2.4 3 1 0 3 3 3 0 Ferrous iron transport protein B zf-4CXXC_R1 PF10497.9 RUS86449.1 - 0.31 11.3 1.9 9.3 6.5 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 P-mevalo_kinase PF04275.14 RUS86450.1 - 4.7e-15 55.5 0.3 8.3e-15 54.7 0.1 1.5 2 0 0 2 2 2 1 Phosphomevalonate kinase TPR_1 PF00515.28 RUS86451.1 - 3.6e-16 58.2 0.4 1.3e-05 24.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS86451.1 - 1.8e-15 56.4 0.0 1.8e-06 27.5 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 RUS86451.1 - 2.3e-15 55.4 0.1 0.00029 20.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS86451.1 - 2e-07 30.7 0.7 0.22 11.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS86451.1 - 1.4e-06 28.2 0.1 0.37 11.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS86451.1 - 0.00031 21.2 0.1 0.54 10.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 RUS86451.1 - 0.011 14.6 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 RUS86451.1 - 0.018 15.7 0.1 2.9 8.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS86451.1 - 0.028 15.2 0.0 29 5.8 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 RUS86451.1 - 0.032 14.3 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TPR_21 PF09976.9 RUS86451.1 - 0.036 13.8 0.0 0.16 11.6 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 RUS86451.1 - 0.067 13.3 0.0 18 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PACT_coil_coil PF10495.9 RUS86451.1 - 0.082 13.5 0.1 0.31 11.7 0.1 1.8 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3856 PF12968.7 RUS86451.1 - 0.11 12.5 0.2 0.41 10.7 0.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) RVT_1 PF00078.27 RUS86452.1 - 1.7e-22 80.1 0.0 6e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 RUS86452.1 - 1e-05 25.0 3.8 1e-05 25.0 3.8 2.6 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 RUS86452.1 - 4.1e-05 23.4 10.6 4.1e-05 23.4 10.6 2.1 2 0 0 2 2 2 1 PHD-finger Pox_vIL-18BP PF05566.12 RUS86452.1 - 0.24 11.6 3.0 4.4 7.5 0.5 2.5 1 1 1 2 2 2 0 Orthopoxvirus interleukin 18 binding protein C1_2 PF03107.16 RUS86452.1 - 4.9 7.6 11.9 4.1 7.8 5.0 2.6 3 0 0 3 3 3 0 C1 domain Abhydrolase_1 PF00561.20 RUS86453.1 - 2.3e-08 34.0 0.0 4.3e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 RUS86453.1 - 9.3e-05 22.6 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 RUS86453.1 - 0.00013 22.6 0.0 0.00016 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 RUS86453.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS86453.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Ndr PF03096.14 RUS86453.1 - 0.051 12.3 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family zf-CCHC PF00098.23 RUS86454.1 - 1.6e-20 72.2 26.1 3.5e-06 26.8 1.3 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 RUS86454.1 - 1.1e-07 31.7 10.2 0.13 12.2 1.7 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 RUS86454.1 - 0.0024 17.6 28.3 0.02 14.7 1.4 4.1 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 RUS86454.1 - 0.0042 16.8 20.5 0.42 10.4 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 RUS86454.1 - 0.13 12.0 20.4 0.18 11.6 1.5 4.1 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger HMMR_N PF15905.5 RUS86455.1 - 9.6e-05 22.0 32.7 9.6e-05 22.0 32.7 8.7 4 3 2 8 8 8 2 Hyaluronan mediated motility receptor N-terminal BST2 PF16716.5 RUS86455.1 - 0.0039 17.7 6.1 0.0039 17.7 6.1 13.4 6 4 8 15 15 15 1 Bone marrow stromal antigen 2 Fez1 PF06818.15 RUS86455.1 - 0.0067 16.9 9.6 0.0067 16.9 9.6 8.6 3 2 6 9 9 9 3 Fez1 T7SS_ESX_EspC PF10824.8 RUS86455.1 - 0.74 10.3 16.0 1.4 9.5 0.0 5.7 7 2 1 8 8 8 0 Excreted virulence factor EspC, type VII ESX diderm 3HCDH_N PF02737.18 RUS86456.1 - 6.4e-59 198.9 0.8 1.5e-58 197.6 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 RUS86456.1 - 2.8e-41 141.5 0.2 4.7e-41 140.8 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 RUS86456.1 - 5.2e-30 103.9 0.0 2.6e-20 72.8 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 RUS86456.1 - 4.6e-27 95.4 0.1 1e-26 94.3 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 RUS86456.1 - 0.00063 19.9 0.1 0.0047 17.1 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 RUS86456.1 - 0.0042 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 RUS86456.1 - 0.0044 16.7 0.5 0.0083 15.8 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 RUS86456.1 - 0.007 16.9 0.1 0.024 15.2 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 RUS86456.1 - 0.016 15.4 0.6 0.07 13.4 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 RUS86456.1 - 0.038 13.2 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DSPc PF00782.20 RUS86457.1 - 4.3e-33 113.9 0.0 5.9e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS86457.1 - 1.5e-06 28.0 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thymosin PF01290.20 RUS86457.1 - 0.0067 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Thymosin beta-4 family Init_tRNA_PT PF04179.12 RUS86457.1 - 0.074 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Sec63 PF02889.16 RUS86458.1 - 7.8e-173 572.5 5.0 1e-91 306.7 0.7 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RUS86458.1 - 3.9e-54 183.1 0.3 2.2e-26 92.7 0.2 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 RUS86458.1 - 2.5e-34 117.8 1.0 2.5e-34 117.8 1.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 RUS86458.1 - 1.5e-25 90.2 0.0 5.8e-14 52.4 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS86458.1 - 1.1e-16 61.2 0.1 6.4e-08 32.9 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 RUS86458.1 - 3.7e-08 33.3 0.0 0.0033 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS86458.1 - 8e-05 22.9 0.0 0.088 13.1 0.1 3.5 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 RUS86458.1 - 0.0013 17.8 0.0 0.69 8.9 0.0 2.9 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 RUS86458.1 - 0.026 14.0 0.0 8.1 5.8 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 RUS86458.1 - 0.094 12.4 0.1 1 9.0 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein FAM184 PF15665.5 RUS86459.1 - 3.7e-05 23.6 10.9 3.7e-05 23.6 10.9 3.4 1 1 2 3 3 3 1 Family with sequence similarity 184, A and B ADIP PF11559.8 RUS86459.1 - 0.0082 16.2 45.8 0.02 15.0 13.8 4.2 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding DUF4143 PF13635.6 RUS86459.1 - 0.067 13.3 0.2 0.23 11.6 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) DUF3584 PF12128.8 RUS86459.1 - 0.32 8.5 36.2 0.46 7.9 36.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SRP54 PF00448.22 RUS86459.1 - 0.48 10.0 4.7 0.098 12.3 0.3 2.0 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Lectin_N PF03954.14 RUS86459.1 - 0.49 10.2 20.2 0.067 12.9 2.9 3.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.11 RUS86459.1 - 0.72 9.7 18.8 3.4 7.5 3.4 3.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HALZ PF02183.18 RUS86459.1 - 0.77 10.0 14.2 2.5 8.4 0.0 5.6 4 1 0 4 4 4 0 Homeobox associated leucine zipper Laminin_II PF06009.12 RUS86459.1 - 0.84 9.7 26.2 0.42 10.6 7.4 3.8 1 1 2 3 3 3 0 Laminin Domain II DUF4407 PF14362.6 RUS86459.1 - 0.98 8.7 31.9 0.13 11.6 15.6 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 RUS86459.1 - 1.7 8.7 15.8 2.7 8.1 3.7 3.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL31 PF15209.6 RUS86459.1 - 2.2 8.1 6.0 1.3 8.8 1.2 3.1 2 2 2 4 4 4 0 Interleukin 31 Spc7 PF08317.11 RUS86459.1 - 2.6 6.8 47.8 0.13 11.1 14.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein FAA_hydro_N_2 PF18288.1 RUS86459.1 - 2.7 8.5 8.4 0.16 12.4 0.8 2.8 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 LPP PF04728.13 RUS86459.1 - 3.9 8.0 10.6 45 4.5 0.1 4.9 3 2 1 4 4 4 0 Lipoprotein leucine-zipper DUF948 PF06103.11 RUS86459.1 - 5.7 7.3 14.0 81 3.6 3.4 4.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sulfotransfer_1 PF00685.27 RUS86460.1 - 4.9e-19 68.8 0.2 6.2e-19 68.5 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS86460.1 - 1.3e-11 45.3 0.0 1.5e-06 28.8 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family COX5A PF02284.16 RUS86460.1 - 0.045 13.8 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va RRM_1 PF00076.22 RUS86462.1 - 8e-17 60.8 0.1 1.3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS86462.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS86462.1 - 0.00066 19.7 1.3 0.00088 19.3 0.1 1.8 2 0 0 2 2 2 1 RNA binding motif DUF809 PF05663.11 RUS86463.1 - 0.099 12.8 2.0 0.13 12.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Kinesin PF00225.23 RUS86464.1 - 2.7e-115 384.8 0.0 2.7e-115 384.8 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS86464.1 - 2.4e-26 92.5 0.1 2.4e-26 92.5 0.1 3.0 4 0 0 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 RUS86464.1 - 1.1e-13 51.8 5.3 1.1e-13 51.8 5.3 6.2 3 3 3 6 6 6 1 Kinesin-associated microtubule-binding Glycos_transf_2 PF00535.26 RUS86465.1 - 6.9e-37 126.9 0.0 1.4e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS86465.1 - 9.6e-27 93.7 3.6 1.5e-26 93.1 3.6 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RUS86465.1 - 2.3e-06 27.7 0.0 7.7e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 RUS86465.1 - 2.6e-05 23.8 0.0 7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 RUS86465.1 - 0.00031 21.4 1.0 0.43 11.4 0.9 2.6 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.9 RUS86465.1 - 0.0014 18.1 0.0 0.0034 16.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PPO1_DWL PF12142.8 RUS86465.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Polyphenol oxidase middle domain UPF0515 PF15135.6 RUS86466.1 - 1.5e-43 149.1 9.1 6.2e-36 124.1 4.9 2.1 2 0 0 2 2 2 2 Uncharacterised protein UPF0515 zf-3CxxC_2 PF17180.4 RUS86466.1 - 0.0079 16.9 13.7 0.13 13.0 2.6 2.4 1 1 1 2 2 2 2 Zinc-binding domain Fer4_16 PF13484.6 RUS86466.1 - 0.26 12.3 5.6 0.51 11.3 0.6 2.9 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Glyco_transf_7C PF02709.14 RUS86467.1 - 6.5e-26 89.8 0.0 1.5e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 RUS86467.1 - 8.9e-22 77.2 0.1 1.4e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 RUS86467.1 - 0.11 11.9 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family 2 GCIP PF13324.6 RUS86468.1 - 0.0012 18.6 0.1 0.0073 15.9 0.0 1.9 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting DUF948 PF06103.11 RUS86468.1 - 4.2 7.7 7.0 46 4.4 2.5 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) 2-Hacid_dh_C PF02826.19 RUS86469.1 - 7e-61 204.7 0.0 2.7e-60 202.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS86469.1 - 8.9e-39 132.2 0.1 1.5e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RUS86469.1 - 0.012 15.8 0.0 0.05 13.8 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 RUS86469.1 - 0.016 14.8 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 RUS86469.1 - 0.083 13.5 0.6 20 5.8 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Neur_chan_LBD PF02931.23 RUS86470.1 - 1e-66 224.5 2.3 1.4e-66 224.0 2.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS86470.1 - 9.5e-40 137.1 0.1 4.8e-34 118.5 0.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region YhhN PF07947.14 RUS86470.1 - 0.018 14.7 0.6 0.018 14.7 0.6 1.6 2 0 0 2 2 2 0 YhhN family Herpes_US9 PF06072.11 RUS86471.1 - 0.18 11.7 0.9 0.38 10.7 0.9 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RNase_H PF00075.24 RUS86472.1 - 1.5e-14 54.4 4.7 1.9e-14 54.0 0.2 3.0 3 1 0 3 3 3 1 RNase H RVT_3 PF13456.6 RUS86472.1 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4864 PF16156.5 RUS86472.1 - 0.1 13.3 0.1 0.26 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Alpha-mann_mid PF09261.11 RUS86472.1 - 0.46 10.7 0.1 0.46 10.7 0.1 2.7 2 1 0 2 2 2 0 Alpha mannosidase middle domain GTP-bdg_M PF16360.5 RUS86473.1 - 0.018 15.6 4.4 4.5 8.0 0.3 3.0 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region LytB_WW PF18342.1 RUS86473.1 - 0.12 12.5 0.9 20 5.4 0.1 2.6 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain FeoB_Cyto PF17910.1 RUS86473.1 - 0.63 10.6 3.4 24 5.6 0.3 2.5 2 0 0 2 2 2 0 FeoB cytosolic helical domain 7tm_1 PF00001.21 RUS86474.1 - 4.6e-21 75.3 14.9 5.5e-21 75.1 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86474.1 - 2.9e-06 26.8 17.5 0.0013 18.1 7.4 2.1 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS86474.1 - 0.00014 21.6 15.4 0.00021 21.0 15.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS86475.1 - 9.1e-21 74.3 13.6 1.2e-20 74.0 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86475.1 - 1.5e-07 31.1 14.7 4.8e-07 29.4 14.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS86475.1 - 0.00012 21.8 14.1 0.00093 18.9 14.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx bZIP_2 PF07716.15 RUS86476.1 - 1.1e-05 25.4 8.2 1.1e-05 25.4 8.2 3.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS86476.1 - 0.00051 20.1 6.6 0.00051 20.1 6.6 2.5 3 0 0 3 3 3 1 bZIP transcription factor COX14 PF14880.6 RUS86477.1 - 0.044 13.6 0.6 0.044 13.6 0.6 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly FTZ PF03867.14 RUS86477.1 - 0.095 12.2 0.7 0.15 11.6 0.7 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region ANAPC_CDC26 PF10471.9 RUS86477.1 - 0.59 11.0 14.1 0.95 10.3 2.3 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF1798 PF08807.10 RUS86477.1 - 3.5 7.8 6.8 0.22 11.7 1.1 1.9 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) SelK_SelG PF10961.8 RUS86477.1 - 6.9 7.4 7.8 17 6.1 2.6 2.8 3 1 0 3 3 3 0 Selenoprotein SelK_SelG Trypsin PF00089.26 RUS86478.1 - 2.9e-39 135.2 0.0 2.3e-37 128.9 0.0 2.1 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS86478.1 - 1.6e-07 32.3 0.0 4.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RUS86478.1 - 0.00087 19.7 0.0 0.016 15.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) SRCR_2 PF15494.6 RUS86478.1 - 0.025 15.1 0.1 0.045 14.3 0.1 1.5 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain zf-C2H2 PF00096.26 RUS86480.1 - 6.4e-27 92.5 36.8 3.6e-05 24.0 2.0 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86480.1 - 6.2e-21 73.3 36.7 0.00098 19.8 0.6 8.0 7 0 0 7 7 7 7 C2H2-type zinc finger BTB PF00651.31 RUS86480.1 - 7e-17 61.7 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 RUS86480.1 - 7.2e-16 57.8 34.9 1.5e-06 28.4 1.3 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS86480.1 - 1.8e-10 40.5 24.3 6.3e-06 26.1 0.1 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS86480.1 - 0.00029 20.5 33.9 0.78 9.6 0.2 8.2 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-met PF12874.7 RUS86480.1 - 0.015 15.7 25.7 0.042 14.2 0.2 6.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RUS86480.1 - 0.036 14.5 0.1 0.036 14.5 0.1 6.4 7 1 1 8 8 7 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 RUS86480.1 - 0.11 12.9 21.2 7.4 7.0 0.1 7.1 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 RUS86480.1 - 0.76 9.9 23.6 0.038 14.1 2.4 5.1 5 0 0 5 5 5 0 Zinc ribbon domain zf_ZIC PF18366.1 RUS86480.1 - 3.1 8.0 5.9 20 5.4 0.1 3.9 3 1 1 4 4 4 0 Zic proteins zinc finger domain SapB_1 PF05184.15 RUS86482.1 - 6.3e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Saposin-like type B, region 1 Metallophos PF00149.28 RUS86483.1 - 1.4e-15 58.4 3.7 2.3e-15 57.7 3.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_SOX PF18371.1 RUS86483.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase PXA PF02194.15 RUS86484.1 - 2.2e-24 86.4 1.8 3.9e-24 85.6 1.8 1.4 1 0 0 1 1 1 1 PXA domain PX PF00787.24 RUS86484.1 - 1.9e-12 47.1 1.8 3.3e-12 46.4 0.9 1.8 2 0 0 2 2 2 1 PX domain CCB1 PF12046.8 RUS86484.1 - 0.084 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PX PF00787.24 RUS86485.1 - 4.4e-09 36.3 0.7 9.2e-09 35.3 0.2 1.7 2 0 0 2 2 2 1 PX domain PT PF04886.12 RUS86486.1 - 4.6e-10 38.9 3.1 0.17 11.4 0.0 6.0 4 2 1 5 5 5 4 PT repeat BLACT_WH PF17778.1 RUS86486.1 - 4.6 7.3 11.9 46 4.1 0.1 5.7 6 1 1 7 7 7 0 Beta-lactamase associated winged helix domain End_beta_propel PF12217.8 RUS86487.1 - 0.086 11.5 5.3 0.098 11.3 5.3 1.0 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase End_beta_barrel PF12195.8 RUS86487.1 - 0.23 11.4 10.4 0.31 11.0 10.4 1.1 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase SSP160 PF06933.11 RUS86487.1 - 0.3 9.3 16.5 0.3 9.2 16.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Orthopox_A5L PF06193.11 RUS86487.1 - 2 7.8 8.4 2.3 7.6 8.4 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Sporozoite_P67 PF05642.11 RUS86487.1 - 2.1 6.3 10.6 2.1 6.3 10.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 RUS86487.1 - 4 5.5 10.1 4 5.5 10.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 RUS86487.1 - 8.5 4.2 5.6 9.4 4.1 5.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cadherin PF00028.17 RUS86488.1 - 3.6e-05 24.1 5.0 0.00017 21.9 0.5 3.0 3 0 0 3 3 3 1 Cadherin domain Fn3_assoc PF13287.6 RUS86488.1 - 0.0082 16.3 0.3 0.021 15.0 0.3 1.7 1 0 0 1 1 1 1 Fn3 associated TFX_C PF14601.6 RUS86489.1 - 7.7e-06 25.8 0.1 32 4.6 0.0 6.2 1 1 6 7 7 7 0 DNA_binding protein, TFX, C-term Glyco_hydro_32N PF00251.20 RUS86489.1 - 1.2e-05 25.0 0.0 2.3 7.7 0.0 4.0 1 1 3 4 4 4 3 Glycosyl hydrolases family 32 N-terminal domain DUF4978 PF16349.5 RUS86489.1 - 6.8e-05 22.6 0.2 18 4.9 0.0 5.5 1 1 4 5 5 5 1 Domain of unknown function (DUF4978) hnRNP_Q_AcD PF18360.1 RUS86489.1 - 7.3e-05 22.6 0.0 13 5.9 0.0 5.7 1 1 5 7 7 7 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain Alpha-amyl_C PF09071.10 RUS86489.1 - 0.023 14.5 4.3 3.1e+02 1.3 0.0 6.3 7 0 0 7 7 7 0 Alpha-amylase, C terminal SLC12 PF03522.15 RUS86489.1 - 0.051 12.6 0.5 48 2.8 0.0 3.8 1 1 4 5 5 5 0 Solute carrier family 12 Cobl PF09469.10 RUS86492.1 - 0.0082 16.4 11.3 68 3.8 0.1 6.7 1 1 7 8 8 8 4 Cordon-bleu ubiquitin-like domain GCP_C_terminal PF04130.13 RUS86494.1 - 3e-20 72.9 0.1 1e-19 71.1 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RUS86494.1 - 7.1e-19 68.6 0.0 1.7e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 RUS86494.1 - 0.00021 19.8 0.5 0.00038 19.0 0.5 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Csm2_III-A PF03750.13 RUS86494.1 - 0.044 14.6 0.0 0.16 12.8 0.0 2.0 1 0 0 1 1 1 0 Csm2 Type III-A DUF4097 PF13349.6 RUS86495.1 - 7.3e-08 32.1 2.2 0.00035 20.0 0.1 2.1 1 1 1 2 2 2 2 Putative adhesin DUF3540 PF12059.8 RUS86495.1 - 4.1e-05 23.5 4.6 0.037 13.9 0.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3540) His_leader PF08047.11 RUS86495.1 - 0.00016 21.5 21.5 27 4.9 0.1 10.2 15 0 0 15 15 15 0 Histidine operon leader peptide SecD-TM1 PF13721.6 RUS86495.1 - 0.0018 18.7 7.1 0.21 12.0 1.4 2.6 1 1 1 2 2 2 2 SecD export protein N-terminal TM region PDDEXK_5 PF11645.8 RUS86495.1 - 0.0021 18.0 13.6 0.25 11.3 0.7 4.1 1 1 2 3 3 3 3 PD-(D/E)XK endonuclease AsmA_1 PF13109.6 RUS86495.1 - 0.0035 16.9 0.5 0.87 9.0 0.1 2.6 1 1 2 3 3 3 3 AsmA-like C-terminal region DUF2345 PF10106.9 RUS86495.1 - 0.011 15.5 0.1 0.29 11.0 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) OEP PF02321.18 RUS86495.1 - 0.021 14.7 4.8 1 9.1 1.5 2.2 1 1 0 2 2 2 0 Outer membrane efflux protein Cys_rich_CPCC PF14206.6 RUS86495.1 - 0.026 14.3 0.1 0.25 11.2 0.0 2.4 1 1 1 2 2 2 0 Cysteine-rich CPCC DUF2140 PF09911.9 RUS86495.1 - 0.035 13.7 2.1 1.1 8.7 0.3 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) Tet_res_leader PF08050.12 RUS86495.1 - 0.047 13.5 20.8 2.1e+02 1.9 0.0 10.5 6 4 6 12 12 12 0 Tetracycline resistance leader peptide Cas_Cas4 PF01930.17 RUS86495.1 - 0.058 13.5 2.1 6.5 6.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF83 FlgT_C PF16538.5 RUS86495.1 - 0.08 13.5 0.9 11 6.6 0.1 2.8 1 1 1 2 2 2 0 Flagellar assembly protein T, C-terminal domain Receptor_2B4 PF11465.8 RUS86495.1 - 0.14 12.4 12.4 20 5.4 1.9 4.1 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Exonuc_VII_L PF02601.15 RUS86495.1 - 4.2 6.8 8.8 4.8 6.7 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit 7tm_1 PF00001.21 RUS86496.1 - 0.041 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) GPR15L PF15854.5 RUS86498.1 - 0.12 12.6 0.2 0.19 12.0 0.2 1.3 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Fibrinogen_BP PF08017.11 RUS86499.1 - 3.5 5.9 63.3 3.8 5.8 63.3 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein 7tm_1 PF00001.21 RUS86500.1 - 2.7e-20 72.8 16.9 3.7e-20 72.4 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86500.1 - 9.4e-17 61.3 13.0 7.6e-16 58.3 13.0 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 RUS86500.1 - 0.00064 19.2 15.1 0.0015 18.0 15.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 RUS86500.1 - 0.018 15.0 0.2 0.018 15.0 0.2 3.0 3 1 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa RDD PF06271.12 RUS86500.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.0 3 1 0 3 3 3 0 RDD family 7TM_GPCR_Srx PF10328.9 RUS86500.1 - 0.41 10.2 18.9 0.029 14.0 12.4 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ras PF00071.22 RUS86502.1 - 4.7e-42 143.3 0.2 6e-42 143.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86502.1 - 3.9e-27 94.9 0.1 6.5e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS86502.1 - 7.1e-11 41.9 0.1 8.7e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS86502.1 - 7e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS86502.1 - 0.0001 21.9 0.4 0.0027 17.3 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RUS86502.1 - 0.001 19.4 0.0 0.0039 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RUS86502.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RUS86502.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RUS86502.1 - 0.0067 16.2 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 RUS86502.1 - 0.014 15.1 0.1 0.2 11.4 0.1 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 RUS86502.1 - 0.017 14.6 0.0 0.056 12.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 RUS86502.1 - 0.024 13.8 0.0 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.20 RUS86502.1 - 0.024 13.8 0.7 4.7 6.3 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RuvB_N PF05496.12 RUS86502.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 RUS86502.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 RUS86502.1 - 0.029 14.8 0.0 0.067 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 RUS86502.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 RUS86502.1 - 0.033 13.9 0.2 0.039 13.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 RUS86502.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain LKAAEAR PF15478.6 RUS86503.1 - 3.2e-48 163.5 7.7 4e-48 163.2 7.7 1.1 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif MBOAT PF03062.19 RUS86504.1 - 1.3e-16 61.0 4.6 1.3e-16 61.0 4.6 1.4 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family YbgT_YccB PF08173.11 RUS86504.1 - 0.14 12.3 0.9 0.51 10.5 0.9 2.0 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Pentapeptide_4 PF13599.6 RUS86505.1 - 6.7e-09 35.8 0.0 0.017 15.3 0.0 3.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) ARS2 PF04959.13 RUS86506.1 - 3.5e-39 135.2 3.9 3.5e-39 135.2 3.9 3.7 4 0 0 4 4 4 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 RUS86506.1 - 4.9e-35 120.1 1.4 4.9e-35 120.1 1.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) RCS1 PF07326.11 RUS86506.1 - 0.026 14.4 1.4 0.056 13.4 1.4 1.6 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 RRM_1 PF00076.22 RUS86506.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deaminase_N PF08451.11 RUS86506.1 - 0.37 11.1 4.1 0.12 12.7 0.3 2.1 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal DUF755 PF05501.11 RUS86506.1 - 2.7 8.3 11.9 0.51 10.6 7.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF5575 PF17738.1 RUS86507.1 - 3.1e-08 33.0 0.3 5.5e-08 32.2 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Acyl-ACP_TE PF01643.17 RUS86507.1 - 8.5e-08 31.8 0.0 2.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-ACP thioesterase FAR1 PF03101.15 RUS86507.1 - 7.4e-07 29.8 0.1 1.8e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Elf1 PF05129.13 RUS86508.1 - 0.07 13.2 1.8 0.39 10.8 0.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DUF1896 PF08989.10 RUS86508.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) DnaJ_CXXCXGXG PF00684.19 RUS86508.1 - 3.4 8.1 5.5 2.1 8.8 0.3 3.0 3 0 0 3 3 3 0 DnaJ central domain zf-RING_9 PF13901.6 RUS86510.1 - 2.2e-10 40.9 7.1 2.7e-10 40.6 7.1 1.1 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 RUS86510.1 - 0.0027 17.6 8.9 0.005 16.7 8.9 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 RUS86510.1 - 0.079 13.0 7.9 0.15 12.1 7.9 1.4 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 RUS86510.1 - 0.26 11.2 9.0 0.74 9.7 9.0 1.8 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.22 RUS86510.1 - 0.82 9.6 10.4 2.4 8.1 10.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RUS86510.1 - 5.8 6.6 12.8 17 5.1 12.8 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 RUS86511.1 - 1.7e-32 113.1 0.1 2.7e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-RING_7 PF02591.15 RUS86511.1 - 1.8 8.8 5.1 3.7 7.8 4.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain PP2C PF00481.21 RUS86513.1 - 1.4e-13 51.1 0.0 3.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SWIM PF04434.17 RUS86514.1 - 3.8e-05 23.3 1.9 7.1e-05 22.4 1.9 1.4 1 0 0 1 1 1 1 SWIM zinc finger Abhydrolase_3 PF07859.13 RUS86515.1 - 2.9e-44 151.5 0.1 4.2e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RUS86515.1 - 1.7e-12 47.0 1.4 9.6e-12 44.5 1.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RUS86515.1 - 8.9e-06 25.3 0.0 2.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 RUS86515.1 - 0.00099 18.7 0.0 0.0084 15.7 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Say1_Mug180 PF10340.9 RUS86515.1 - 0.41 9.4 0.8 2.4 6.9 0.7 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Ribosomal_L18p PF00861.22 RUS86516.1 - 1.7e-08 34.8 0.0 2.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7tm_1 PF00001.21 RUS86517.1 - 1.8e-17 63.5 5.8 5.8e-17 61.9 5.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1180 PF06679.12 RUS86517.1 - 0.028 14.9 0.1 0.06 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Spt20 PF12090.8 RUS86517.1 - 0.049 13.2 0.5 0.065 12.8 0.5 1.1 1 0 0 1 1 1 0 Spt20 family DHHC PF01529.20 RUS86517.1 - 0.1 12.7 6.1 1.2 9.3 4.0 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4834 PF16118.5 RUS86517.1 - 0.18 12.8 0.2 0.41 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DEPP PF15343.6 RUS86517.1 - 0.42 10.7 5.6 0.66 10.0 5.6 1.2 1 0 0 1 1 1 0 Decidual protein induced by progesterone family Methyltransf_11 PF08241.12 RUS86518.1 - 5.8e-17 62.1 0.0 1.4e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS86518.1 - 2e-16 60.5 0.0 5.6e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS86518.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS86518.1 - 1.6e-09 37.4 0.0 4.2e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS86518.1 - 2.9e-07 31.2 0.0 8.3e-07 29.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS86518.1 - 1.8e-06 27.9 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 RUS86518.1 - 2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 RUS86518.1 - 0.0029 17.5 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase tRNA_U5-meth_tr PF05958.11 RUS86518.1 - 0.005 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_29 PF03141.16 RUS86518.1 - 0.0067 15.0 0.0 0.009 14.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 RUS86518.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 RUS86518.1 - 0.016 14.6 0.0 0.47 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 RUS86518.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 RUS86518.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 RUS86518.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) ACBP PF00887.19 RUS86519.1 - 3.6e-19 68.8 0.8 6.5e-19 67.9 0.8 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Pro_isomerase PF00160.21 RUS86520.1 - 1.8e-46 158.3 0.3 1.8e-46 158.3 0.3 2.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Porin_2 PF02530.14 RUS86520.1 - 0.078 12.2 1.0 0.17 11.2 1.0 1.5 1 0 0 1 1 1 0 Porin subfamily MEIOC PF15189.6 RUS86522.1 - 2.9e-68 228.7 3.6 5.1e-45 153.1 0.4 2.1 1 1 1 2 2 2 2 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF4912 PF16258.5 RUS86522.1 - 0.11 12.7 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4912) MEIOC PF15189.6 RUS86524.1 - 2.1e-07 30.7 0.9 3.4e-07 30.0 0.9 1.3 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC GST_C_6 PF17171.4 RUS86525.1 - 5.2e-21 74.2 0.0 1.4e-20 72.8 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 RUS86525.1 - 2.1e-18 66.9 0.0 4.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 RUS86525.1 - 9.4e-17 61.5 0.0 5.4e-16 59.0 0.0 2.1 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 RUS86525.1 - 1.5e-05 24.9 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS86525.1 - 0.017 15.3 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS86525.1 - 0.02 15.1 0.0 0.16 12.2 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain TIR_2 PF13676.6 RUS86527.1 - 1.6e-08 35.2 0.0 3.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 RUS86527.1 - 3.9e-08 33.3 0.0 6.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain Death PF00531.22 RUS86527.1 - 7.3e-05 22.8 0.0 0.00048 20.2 0.0 2.2 2 0 0 2 2 2 1 Death domain PAP2 PF01569.21 RUS86528.1 - 9.4e-18 64.3 4.9 9.4e-18 64.3 4.9 2.7 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 RUS86528.1 - 0.95 9.6 5.2 16 5.6 0.1 3.4 2 1 0 2 2 2 0 Divergent PAP2 family WD40 PF00400.32 RUS86529.1 - 4.8e-34 115.8 23.0 3.2e-07 30.9 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86529.1 - 5.5e-13 49.0 0.1 0.016 15.5 0.1 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Golgin_A5 PF09787.9 RUS86529.1 - 0.00018 21.1 0.8 0.00018 21.1 0.8 1.6 1 1 1 2 2 2 1 Golgin subfamily A member 5 eIF2A PF08662.11 RUS86529.1 - 0.0016 18.4 2.5 1.2 9.0 2.8 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RUS86529.1 - 0.0044 16.0 3.9 1.2 8.1 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CorA PF01544.18 RUS86529.1 - 0.16 11.3 0.8 0.26 10.6 0.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prog_receptor PF02161.15 RUS86529.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Progesterone receptor Cep57_CLD_2 PF14197.6 RUS86529.1 - 7.1 6.8 11.9 9.4 6.4 0.8 3.9 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 Tubulin-binding PF00418.19 RUS86530.1 - 1.4e-82 271.3 33.7 5.4e-14 51.9 0.1 8.1 8 0 0 8 8 8 8 Tau and MAP protein, tubulin-binding repeat DUF536 PF04394.14 RUS86530.1 - 0.02 14.8 2.4 1.6 8.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF536 DUF1775 PF07987.11 RUS86530.1 - 1.1 9.5 7.1 7.8 6.7 0.4 2.8 1 1 3 4 4 4 0 Domain of unkown function (DUF1775) SH3_15 PF18346.1 RUS86530.1 - 3.6 8.0 9.4 1e+02 3.3 9.4 2.5 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain Tubulin-binding PF00418.19 RUS86531.1 - 4.3e-54 180.2 17.1 2.2e-09 37.2 0.1 7.9 8 0 0 8 8 8 7 Tau and MAP protein, tubulin-binding repeat RhoGAP PF00620.27 RUS86534.1 - 1.7e-33 115.6 0.0 4.5e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain ig PF00047.25 RUS86535.1 - 0.016 15.3 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 RUS86535.1 - 0.086 13.4 0.0 15 6.2 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin domain Kinesin PF00225.23 RUS86536.1 - 6.2e-92 308.1 0.1 4.2e-91 305.3 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS86536.1 - 1.8e-16 60.4 0.0 5.1e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 RUS86536.1 - 0.0002 21.6 10.5 0.0017 18.5 0.3 4.2 3 1 0 4 4 4 2 Kinesin-associated FHA PF00498.26 RUS86536.1 - 0.078 13.3 0.1 2.8 8.4 0.0 3.0 2 0 0 2 2 2 0 FHA domain Peptidase_S51 PF03575.17 RUS86538.1 - 0.097 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S51 Ribosomal_L18_c PF14204.6 RUS86538.1 - 8 7.5 7.8 1.5 9.8 1.7 3.1 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Corona_3 PF04694.12 RUS86540.1 - 0.18 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Coronavirus ORF3 protein SlyX PF04102.12 RUS86540.1 - 1.2 9.8 8.1 0.56 10.9 2.4 3.3 2 0 0 2 2 2 0 SlyX SOAR PF16533.5 RUS86540.1 - 7 6.7 10.3 0.51 10.3 2.5 3.2 3 0 0 3 3 3 0 STIM1 Orai1-activating region C2 PF00168.30 RUS86541.1 - 1.7e-21 76.4 0.0 1.1e-09 38.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain Amnionless PF14828.6 RUS86541.1 - 0.00046 19.1 0.9 0.016 14.1 0.1 2.3 2 1 0 2 2 2 1 Amnionless Orf78 PF06024.12 RUS86541.1 - 0.024 14.9 0.0 0.024 14.9 0.0 3.6 3 1 0 3 3 3 0 Orf78 (ac78) SID-1_RNA_chan PF13965.6 RUS86541.1 - 0.072 11.5 0.2 0.36 9.2 0.0 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Pex24p PF06398.11 RUS86541.1 - 0.086 11.8 0.2 1.1 8.2 0.3 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF2207 PF09972.9 RUS86541.1 - 0.11 11.2 0.0 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 RUS86541.1 - 0.13 12.0 0.2 5 6.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF4013 PF13197.6 RUS86541.1 - 0.28 11.0 6.0 0.32 10.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Pox_EPC_I2-L1 PF12575.8 RUS86541.1 - 1.1 9.6 9.4 0.49 10.7 0.8 2.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DHHC PF01529.20 RUS86541.1 - 1.4 9.0 5.3 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 RUS86541.1 - 2.2 7.9 7.2 49 3.5 6.1 2.7 2 1 0 2 2 2 0 Tetraspanin family DUF2312 PF10073.9 RUS86542.1 - 0.24 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF5345 PF17280.2 RUS86542.1 - 0.81 9.7 3.6 1.3 9.0 3.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Ependymin PF00811.18 RUS86543.1 - 1.7e-33 115.5 0.0 2.4e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ependymin Spec3 PF15795.5 RUS86545.1 - 7.9e-29 100.0 9.8 1.3e-28 99.3 9.8 1.4 1 0 0 1 1 1 1 Ectodermal ciliogenesis protein VWC PF00093.18 RUS86546.1 - 0.00075 19.8 1.7 0.21 12.0 0.5 2.1 1 1 1 2 2 2 2 von Willebrand factor type C domain DUF1508 PF07411.12 RUS86546.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Ion_trans_2 PF07885.16 RUS86549.1 - 7.5e-24 83.5 9.6 1.3e-15 57.1 6.1 2.4 2 0 0 2 2 2 2 Ion channel Sm_multidrug_ex PF06695.11 RUS86549.1 - 0.005 17.5 0.2 0.014 16.1 0.0 1.7 2 0 0 2 2 2 1 Putative small multi-drug export protein Transposase_1 PF01359.18 RUS86550.1 - 1e-18 66.9 0.0 2.1e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS86550.1 - 2e-06 27.6 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS86550.1 - 0.00011 22.3 0.2 0.00031 20.9 0.2 1.8 1 0 0 1 1 1 1 Transposase DUF977 PF06163.11 RUS86550.1 - 0.04 13.9 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS86550.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ras PF00071.22 RUS86551.1 - 1.4e-42 145.1 0.0 1.7e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86551.1 - 8.1e-21 74.5 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS86551.1 - 0.0002 20.8 0.0 0.00049 19.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS86551.1 - 0.023 14.6 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 RUS86551.1 - 0.044 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS86551.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RUS86551.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS86551.1 - 0.089 13.1 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RUS86551.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RUS86551.1 - 0.19 11.2 0.3 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Ank_2 PF12796.7 RUS86553.1 - 5.3e-40 135.9 3.6 4.3e-12 46.5 0.1 4.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86553.1 - 3.4e-36 123.1 7.3 1.2e-10 41.7 0.0 7.1 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS86553.1 - 2.7e-29 98.0 1.1 0.00061 20.0 0.1 8.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 RUS86553.1 - 8.2e-26 89.7 9.1 0.00028 21.1 0.1 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS86553.1 - 1.6e-22 78.9 11.7 0.0084 16.5 0.1 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.7 RUS86554.1 - 4.2e-29 101.0 0.5 2.9e-11 43.8 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86554.1 - 5e-28 97.1 0.5 6.5e-08 33.0 0.0 5.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS86554.1 - 1.4e-23 82.6 1.7 8.3e-07 29.2 0.0 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS86554.1 - 9.1e-22 76.5 2.5 3.4e-05 24.1 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 RUS86554.1 - 1e-17 62.4 0.9 0.0016 18.8 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat PliI PF16743.5 RUS86556.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme MgtE_N PF03448.17 RUS86557.1 - 6.5e-11 42.8 26.4 6.7e-08 33.1 15.1 2.4 1 1 1 2 2 2 2 MgtE intracellular N domain DUF2267 PF10025.9 RUS86557.1 - 3.5e-05 24.1 10.9 0.63 10.3 1.5 3.9 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2267) FliG_C PF01706.16 RUS86557.1 - 0.14 12.4 0.4 1.9 8.7 0.1 2.1 1 1 0 2 2 2 0 FliG C-terminal domain RAC_head PF16717.5 RUS86557.1 - 2.1 9.4 4.0 44 5.1 0.2 2.8 1 1 2 3 3 3 0 Ribosome-associated complex head domain T4_baseplate PF12322.8 RUS86557.1 - 2.3 7.6 8.6 1.9 7.9 0.2 2.8 1 1 3 4 4 4 0 T4 bacteriophage base plate protein FlaG PF03646.15 RUS86557.1 - 7.5 6.8 8.1 14 5.9 0.2 4.1 1 1 1 3 3 3 0 FlaG protein SRP54 PF00448.22 RUS86559.1 - 3.5e-78 261.7 2.2 1.9e-77 259.4 0.3 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RUS86559.1 - 2.5e-30 105.0 2.1 2.5e-30 105.0 2.1 3.6 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 RUS86559.1 - 2.1e-19 69.5 1.1 6.7e-19 67.9 1.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 RUS86559.1 - 1.5e-06 27.9 1.3 3.1e-05 23.6 1.5 2.5 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RUS86559.1 - 7.8e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 RUS86559.1 - 8.2e-06 25.9 0.0 4.9e-05 23.4 0.0 2.3 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 RUS86559.1 - 5.3e-05 22.7 0.6 0.044 13.2 0.6 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ResIII PF04851.15 RUS86559.1 - 0.00047 20.2 0.5 0.0022 18.0 0.5 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 RUS86559.1 - 0.001 19.5 0.2 0.001 19.5 0.2 2.7 3 1 0 3 3 2 1 AAA domain AAA PF00004.29 RUS86559.1 - 0.0012 19.2 4.8 0.021 15.2 0.2 3.9 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 RUS86559.1 - 0.0015 17.6 0.2 0.021 13.8 0.0 2.7 3 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 RUS86559.1 - 0.0021 18.4 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 RUS86559.1 - 0.0027 17.8 0.2 0.017 15.2 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase APS_kinase PF01583.20 RUS86559.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 RUS86559.1 - 0.0054 16.5 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 RUS86559.1 - 0.0082 16.0 0.5 2.8 7.7 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 RUS86559.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS86559.1 - 0.014 16.0 0.0 0.074 13.6 0.1 2.3 2 1 0 2 2 1 0 AAA domain DUF2209 PF09974.9 RUS86559.1 - 0.015 15.7 0.2 0.038 14.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_22 PF13401.6 RUS86559.1 - 0.018 15.3 0.6 0.12 12.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 RUS86559.1 - 0.024 14.6 0.0 0.071 13.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2713 PF10897.8 RUS86559.1 - 0.025 14.2 0.2 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) ArsA_ATPase PF02374.15 RUS86559.1 - 0.028 13.6 0.0 0.028 13.6 0.0 3.0 3 0 0 3 3 3 0 Anion-transporting ATPase 6PF2K PF01591.18 RUS86559.1 - 0.035 13.4 0.0 0.092 12.0 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 RUS86559.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RUS86559.1 - 0.038 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 RUS86559.1 - 0.039 13.8 1.0 2 8.2 1.0 2.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RUS86559.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 RUS86559.1 - 0.05 12.8 0.4 0.92 8.6 0.0 2.5 2 1 0 3 3 3 0 G-protein alpha subunit Thymidylate_kin PF02223.17 RUS86559.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase PduV-EutP PF10662.9 RUS86559.1 - 0.071 12.9 0.4 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 RUS86559.1 - 0.083 12.7 0.8 0.27 11.0 0.1 2.3 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DNA_pol_E_B PF04042.16 RUS86560.1 - 3.4e-25 88.7 0.0 3.2e-24 85.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 RUS86560.1 - 1.3e-18 67.9 1.1 2e-18 67.3 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Kinesin PF00225.23 RUS86561.1 - 6.9e-116 386.8 1.3 6.9e-116 386.8 1.3 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS86561.1 - 6.6e-29 100.8 1.0 4e-28 98.2 0.1 3.0 2 0 0 2 2 2 1 Microtubule binding PX PF00787.24 RUS86561.1 - 3.5e-12 46.3 0.2 1.2e-11 44.5 0.2 2.0 1 0 0 1 1 1 1 PX domain FHA PF00498.26 RUS86561.1 - 8.1e-06 26.1 0.0 0.00034 20.9 0.0 3.4 3 0 0 3 3 3 1 FHA domain Kinesin_assoc PF16183.5 RUS86561.1 - 2.2e-05 24.7 3.6 0.00012 22.3 1.3 5.8 2 2 4 7 7 7 2 Kinesin-associated Yop-YscD_cpl PF16697.5 RUS86561.1 - 0.00076 19.8 0.2 0.0074 16.6 0.0 2.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF743 PF05332.11 RUS86561.1 - 0.0082 16.2 2.5 0.0082 16.2 2.5 5.3 4 3 4 8 8 8 1 Protein of unknown function (DUF743) Cwf_Cwc_15 PF04889.12 RUS86562.1 - 3.1e-07 30.4 37.0 3.1e-07 30.4 37.0 2.3 2 0 0 2 2 1 1 Cwf15/Cwc15 cell cycle control protein SpoIIP PF07454.11 RUS86562.1 - 0.00079 19.0 38.8 0.0044 16.5 11.8 2.3 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 RUS86562.1 - 0.0018 16.6 72.3 0.0019 16.5 30.2 2.2 2 0 0 2 2 2 2 Nop14-like family CDC27 PF09507.10 RUS86562.1 - 0.002 17.6 35.3 0.002 17.6 35.3 2.1 2 0 0 2 2 1 1 DNA polymerase subunit Cdc27 DUF3807 PF12720.7 RUS86562.1 - 0.0051 17.1 52.1 0.015 15.6 27.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3807) TFIIA PF03153.13 RUS86562.1 - 0.0056 16.7 24.6 0.0056 16.7 24.6 2.3 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RUS86562.1 - 0.007 15.8 22.8 0.007 15.8 22.8 2.8 2 1 0 2 2 1 1 BUD22 FAM60A PF15396.6 RUS86562.1 - 0.15 12.1 41.8 0.76 9.7 4.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A AF-4 PF05110.13 RUS86562.1 - 0.3 9.1 45.0 0.38 8.8 45.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4045 PF13254.6 RUS86562.1 - 0.55 9.8 33.1 0.59 9.7 12.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Connexin PF00029.19 RUS86562.1 - 0.72 9.6 43.9 0.66 9.7 14.0 2.1 2 0 0 2 2 2 0 Connexin Gti1_Pac2 PF09729.9 RUS86562.1 - 1.2 9.2 30.5 1.6 8.8 15.4 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family BORG_CEP PF14957.6 RUS86562.1 - 1.5 9.9 27.8 0.82 10.8 10.6 2.2 2 0 0 2 2 2 0 Cdc42 effector FAM76 PF16046.5 RUS86562.1 - 1.6 8.0 38.8 2.4 7.4 4.7 2.1 2 0 0 2 2 2 0 FAM76 protein FGF-BP1 PF06473.12 RUS86562.1 - 1.7 8.4 47.7 0.16 11.8 23.7 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DAG_kinase_N PF14513.6 RUS86562.1 - 2 8.6 25.5 0.4 10.9 10.2 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SLC12 PF03522.15 RUS86562.1 - 2.1 7.3 33.7 0.69 8.9 6.0 2.0 2 0 0 2 2 2 0 Solute carrier family 12 AAA_11 PF13086.6 RUS86562.1 - 3.8 7.2 34.5 0.086 12.6 10.8 2.1 2 0 0 2 2 2 0 AAA domain EIIBC-GUT_N PF03612.14 RUS86562.1 - 4.6 6.9 31.9 1.4 8.6 8.6 2.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus WD40 PF00400.32 RUS86563.1 - 8e-32 108.8 33.9 0.00095 19.9 1.0 10.9 12 1 0 12 12 12 7 WD domain, G-beta repeat HELP PF03451.14 RUS86563.1 - 3e-29 100.7 0.0 6.1e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 RUS86563.1 - 7.4e-12 45.4 1.0 1.9e-05 24.9 0.0 6.9 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RUS86563.1 - 0.039 13.0 0.1 0.086 11.9 0.1 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Ge1_WD40 PF16529.5 RUS86563.1 - 0.054 12.4 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 RUS86563.1 - 0.13 12.2 0.0 49 3.9 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal DUF5557 PF17712.1 RUS86563.1 - 0.15 12.0 0.0 0.57 10.2 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5557) DUF4706 PF15797.5 RUS86564.1 - 3.7e-22 78.8 0.2 1.3e-21 77.1 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4706) PPDK_N PF01326.19 RUS86564.1 - 0.16 11.2 1.6 0.31 10.3 1.6 1.5 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain E1_dh PF00676.20 RUS86565.1 - 3.6e-106 354.5 0.1 4.5e-106 354.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 RUS86565.1 - 0.0014 18.4 0.1 0.0068 16.2 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 RUS86565.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SNRNP27 PF08648.12 RUS86565.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.6 3 0 0 3 3 3 0 U4/U6.U5 small nuclear ribonucleoproteins zf-H2C2_2 PF13465.6 RUS86566.1 - 1.9e-10 40.7 15.6 8e-08 32.4 5.5 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86566.1 - 1e-05 25.7 21.1 2.9e-05 24.3 8.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86566.1 - 0.056 14.3 6.4 0.056 14.3 6.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 RUS86566.1 - 0.18 11.4 10.0 0.77 9.4 1.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS86566.1 - 0.21 11.8 7.7 0.47 10.6 7.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 RUS86566.1 - 0.29 10.9 9.4 0.27 11.1 1.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Fer4_10 PF13237.6 RUS86566.1 - 1.3 9.2 10.1 17 5.6 2.1 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain ADK_lid PF05191.14 RUS86566.1 - 2.7 8.1 7.4 6.9 6.8 7.4 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-trcl PF13451.6 RUS86566.1 - 2.7 7.9 9.2 10 6.1 0.9 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-LYAR PF08790.11 RUS86566.1 - 7 6.6 11.3 2.6 8.0 1.4 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 RUS86567.1 - 0.00021 21.6 12.2 0.012 16.1 3.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain Lectin_C PF00059.21 RUS86568.1 - 1.8e-09 38.3 0.0 2e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain Phage_TAC_3 PF06896.11 RUS86569.1 - 0.0013 19.3 4.0 16 6.1 0.0 4.9 5 1 1 6 6 6 2 Phage tail assembly chaperone proteins, TAC PhnA_Zn_Ribbon PF08274.12 RUS86569.1 - 0.058 13.4 4.8 91 3.1 0.0 4.9 5 0 0 5 5 5 0 PhnA Zinc-Ribbon Ank_2 PF12796.7 RUS86573.1 - 1.9e-26 92.5 5.1 5.4e-11 42.9 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86573.1 - 2.1e-19 69.6 4.9 1.9e-05 25.1 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS86573.1 - 8.1e-16 57.9 5.2 3.3e-06 27.3 0.4 4.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS86573.1 - 9.7e-12 44.8 0.8 0.0039 17.6 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 RUS86573.1 - 3.4e-10 39.3 2.0 0.03 14.8 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat DUF249 PF03158.13 RUS86573.1 - 0.025 14.3 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Multigene family 530 protein MobB PF03205.14 RUS86573.1 - 0.1 12.5 0.0 5 7.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HLH PF00010.26 RUS86574.1 - 1e-12 47.8 0.9 1e-12 47.8 0.9 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain VCBS PF13517.6 RUS86575.1 - 0.00043 20.8 1.5 0.058 14.0 0.1 2.2 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RUS86575.1 - 0.034 14.3 0.1 0.086 13.0 0.0 1.8 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.6 RUS86576.1 - 1.7e-13 50.9 2.1 0.0015 19.1 0.1 4.1 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 RUS86576.1 - 2.5e-07 30.7 8.5 0.0047 17.0 0.9 3.6 3 0 0 3 3 3 2 FG-GAP repeat PliI PF16743.5 RUS86576.1 - 0.00074 19.3 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 2 Periplasmic lysozyme inhibitor of I-type lysozyme TcdB_toxin_midN PF12256.8 RUS86576.1 - 0.011 15.1 0.2 6 6.2 0.0 3.1 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 RUS86576.1 - 0.32 11.2 3.3 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_5 PF13202.6 RUS86576.1 - 9.3 5.9 9.1 8.8 6.0 0.1 3.2 3 0 0 3 3 3 0 EF hand Phospholip_B PF04916.13 RUS86577.1 - 3e-168 560.7 2.0 3.7e-168 560.4 2.0 1.0 1 0 0 1 1 1 1 Phospholipase B Neur_chan_LBD PF02931.23 RUS86578.1 - 4.6e-36 124.3 0.0 6.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS86578.1 - 1.6e-25 90.6 7.6 6.3e-23 82.1 6.0 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Adipogenin PF15202.6 RUS86578.1 - 0.08 13.0 6.8 3.2 7.9 0.1 3.1 3 0 0 3 3 3 0 Adipogenin DUF1218 PF06749.12 RUS86578.1 - 0.11 13.1 0.8 7.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Tetraspanin PF00335.20 RUS86578.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF4381 PF14316.6 RUS86578.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2070 PF09843.9 RUS86578.1 - 0.13 10.6 6.5 0.19 9.9 6.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF21 PF01595.20 RUS86578.1 - 0.45 10.2 4.5 1.1 8.9 4.5 1.6 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF2417 PF10329.9 RUS86578.1 - 0.53 9.7 8.4 0.04 13.3 3.5 1.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Neur_chan_LBD PF02931.23 RUS86579.1 - 1.5e-37 129.1 0.0 2.1e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS86579.1 - 8.5e-24 84.9 10.1 1.3e-23 84.3 7.2 2.0 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Imm26 PF15428.6 RUS86579.1 - 0.026 14.8 0.2 0.45 10.8 0.0 2.7 4 0 0 4 4 4 0 Immunity protein 26 DUF4381 PF14316.6 RUS86579.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adipogenin PF15202.6 RUS86579.1 - 0.34 10.9 6.9 3.3 7.8 0.2 3.0 3 0 0 3 3 3 0 Adipogenin Neur_chan_memb PF02932.16 RUS86580.1 - 8.4e-25 88.2 11.5 4.7e-24 85.8 7.3 2.1 1 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4381 PF14316.6 RUS86580.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1218 PF06749.12 RUS86580.1 - 0.043 14.3 1.0 4.9 7.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) TRF PF08558.10 RUS86580.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Imm26 PF15428.6 RUS86580.1 - 0.15 12.3 0.2 0.62 10.3 0.0 2.1 3 0 0 3 3 3 0 Immunity protein 26 Shisa PF13908.6 RUS86580.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TPR_21 PF09976.9 RUS86580.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Adipogenin PF15202.6 RUS86580.1 - 0.25 11.4 7.7 2.9 8.0 0.1 2.8 3 0 0 3 3 3 0 Adipogenin DUF3328 PF11807.8 RUS86580.1 - 2.6 7.8 4.7 0.3 10.8 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) TMEM154 PF15102.6 RUS86580.1 - 5.2 7.0 6.8 5.3 6.9 0.4 2.3 2 0 0 2 2 2 0 TMEM154 protein family PAS_3 PF08447.12 RUS86581.1 - 1.9e-17 63.3 0.0 2.5e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 RUS86581.1 - 6.9e-12 45.5 0.1 3.5e-10 40.0 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 RUS86581.1 - 4.3e-07 29.9 0.0 4.4e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 RUS86581.1 - 0.00011 22.4 0.0 0.44 10.8 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 RUS86581.1 - 0.00027 21.6 0.2 0.0019 18.8 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 RUS86581.1 - 0.0012 19.1 0.0 0.7 10.2 0.0 2.9 3 0 0 3 3 3 2 PAS fold PTS_2-RNA PF01885.16 RUS86582.1 - 5.1e-49 166.8 0.1 3.4e-46 157.6 0.0 2.1 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family adh_short PF00106.25 RUS86583.1 - 4.5e-27 94.8 0.1 5.1e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS86583.1 - 7.7e-19 68.2 0.0 9.3e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS86583.1 - 8.5e-08 32.3 0.1 1.1e-07 31.9 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 RUS86583.1 - 0.0012 18.3 0.1 0.0015 18.0 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 RUS86583.1 - 0.0042 16.6 0.1 0.0044 16.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RUS86583.1 - 0.0086 15.2 0.2 0.012 14.8 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RUS86583.1 - 0.038 13.0 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 RUS86583.1 - 0.048 13.6 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RUS86583.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 RUS86583.1 - 0.13 11.7 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAC PF01849.18 RUS86585.1 - 4.2e-25 87.5 0.6 1.1e-23 82.9 0.1 2.5 2 0 0 2 2 2 2 NAC domain Radial_spoke PF04712.12 RUS86586.1 - 0.0028 16.7 2.9 0.0033 16.4 2.9 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein FAM176 PF14851.6 RUS86586.1 - 0.04 13.6 3.5 0.066 12.9 3.5 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 RUS86586.1 - 0.063 13.1 6.1 0.085 12.6 6.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 RUS86586.1 - 0.063 13.7 2.7 0.098 13.1 2.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adeno_terminal PF02459.15 RUS86586.1 - 0.12 10.7 0.2 0.12 10.7 0.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DNA_pol_phi PF04931.13 RUS86586.1 - 3.4 5.7 6.5 4.1 5.4 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CX9C PF16860.5 RUS86587.1 - 5.5e-07 29.5 8.6 1.7e-05 24.7 2.1 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 RUS86587.1 - 0.0001 22.3 5.0 0.0001 22.3 5.0 2.8 2 1 1 3 3 3 1 CHCH domain COX6B PF02297.17 RUS86587.1 - 0.025 14.8 4.4 0.025 14.8 4.4 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 RUS86587.1 - 0.12 12.4 8.1 0.11 12.6 1.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 RUS86587.1 - 6 7.2 10.6 7.7 6.9 0.6 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Sulfatase PF00884.23 RUS86588.1 - 9.1e-73 245.3 0.0 1.4e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 RUS86588.1 - 3.5e-31 108.5 0.2 5.5e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 RUS86588.1 - 1.5e-08 34.6 0.0 5.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfotransfer_1 PF00685.27 RUS86589.1 - 1.1e-10 41.5 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS86589.1 - 0.0021 18.5 0.1 0.0065 16.9 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 RUS86590.1 - 6.9e-05 23.3 0.0 0.00015 22.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS86590.1 - 0.00034 20.2 0.2 0.0005 19.6 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase domain EF-hand_13 PF17958.1 RUS86592.1 - 7.2e-35 118.7 0.0 3.8e-34 116.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RUS86592.1 - 1.3e-20 73.6 8.3 1.8e-19 70.0 1.9 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS86592.1 - 1.6e-05 24.2 0.4 0.00018 20.9 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 RUS86592.1 - 9.5e-05 21.7 4.9 0.027 14.0 0.1 5.1 6 0 0 6 6 6 1 EF hand EF-hand_6 PF13405.6 RUS86592.1 - 0.00045 19.9 3.5 0.082 12.9 0.1 4.7 6 0 0 6 6 6 1 EF-hand domain EF-hand_8 PF13833.6 RUS86592.1 - 0.19 11.6 4.0 0.33 10.8 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS86592.1 - 0.23 11.8 2.4 6.4 7.1 0.4 2.5 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DNA_gyraseA_C PF03989.13 RUS86593.1 - 0.00064 19.2 3.0 4.2 6.9 0.0 4.2 5 0 0 5 5 5 2 DNA gyrase C-terminal domain, beta-propeller Nif11 PF07862.11 RUS86593.1 - 0.034 14.5 0.0 8.1 6.8 0.0 2.6 1 1 2 3 3 3 0 Nif11 domain D-ser_dehydrat PF14031.6 RUS86593.1 - 0.33 11.6 8.4 28 5.5 1.3 3.6 1 1 2 3 3 3 0 Putative serine dehydratase domain DUF2118 PF09891.9 RUS86593.1 - 3.4 7.6 8.9 4.8 7.1 1.1 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF4222 PF13973.6 RUS86593.1 - 6.3 6.5 18.8 3.8 7.2 0.2 5.6 3 2 4 7 7 7 0 Domain of unknown function (DUF4222) SpoIIP PF07454.11 RUS86594.1 - 4.2 6.7 15.2 0.093 12.2 3.4 2.1 1 1 1 2 2 2 0 Stage II sporulation protein P (SpoIIP) AlphaC_C PF17480.2 RUS86595.1 - 0.049 13.7 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 AlphaC C-terminal PTE PF02126.18 RUS86596.1 - 8.9e-93 311.0 0.0 1e-92 310.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family PHD PF00628.29 RUS86597.1 - 1.8e-14 53.4 19.3 6.9e-09 35.5 3.1 2.6 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 RUS86597.1 - 4e-11 43.2 0.0 7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS86597.1 - 2.6e-07 30.7 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHD_4 PF16866.5 RUS86597.1 - 0.0019 18.2 7.2 0.0019 18.2 7.2 2.8 1 1 1 2 2 2 1 PHD-finger C1_1 PF00130.22 RUS86597.1 - 0.0049 16.7 16.9 0.11 12.4 0.7 2.4 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 RUS86597.1 - 0.027 14.0 12.4 0.24 11.0 0.1 3.1 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 RUS86597.1 - 0.33 11.3 14.4 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 C1 domain DUF3915 PF13054.6 RUS86598.1 - 3.4 7.7 10.4 5.9 6.9 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS86598.1 - 5 5.3 14.8 8 4.6 14.8 1.3 1 0 0 1 1 1 0 Atrophin-1 family Death PF00531.22 RUS86600.1 - 2.6e-05 24.3 1.5 0.00017 21.7 0.2 2.6 2 0 0 2 2 2 1 Death domain TFIIA PF03153.13 RUS86600.1 - 0.039 13.9 24.0 0.06 13.3 24.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAD_SRA PF02182.17 RUS86600.1 - 0.13 12.0 3.3 0.24 11.1 3.3 1.3 1 0 0 1 1 1 0 SAD/SRA domain Suf PF05843.14 RUS86600.1 - 0.24 11.3 16.2 0.42 10.6 16.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MMR1 PF08505.10 RUS86600.1 - 0.67 10.2 15.1 1.2 9.4 15.1 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4569 PF15133.6 RUS86600.1 - 1.4 8.6 15.4 2.3 7.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) PAT1 PF09770.9 RUS86600.1 - 3.9 5.6 20.1 5.5 5.1 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 RUS86600.1 - 4.3 4.3 11.4 5.6 4.0 11.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Orf78 PF06024.12 RUS86600.1 - 4.8 7.5 5.6 12 6.2 5.6 1.7 1 0 0 1 1 1 0 Orf78 (ac78) V_ATPase_I PF01496.19 RUS86600.1 - 5.2 4.9 9.3 7.3 4.4 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 RUS86600.1 - 6.8 4.7 11.1 9.4 4.2 11.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 RUS86600.1 - 7.1 6.6 11.4 11 6.0 11.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Tau95_N PF17682.1 RUS86600.1 - 7.5 6.8 9.7 11 6.2 8.1 2.0 2 0 0 2 2 2 0 Tau95 Triple barrel domain Dimer_Tnp_hAT PF05699.14 RUS86601.1 - 0.045 13.5 38.0 3.9 7.3 1.0 7.3 1 1 8 9 9 9 0 hAT family C-terminal dimerisation region FTH PF01827.27 RUS86601.1 - 1.8 8.3 8.9 32 4.3 0.4 4.2 1 1 5 6 6 6 0 FTH domain Ank_5 PF13857.6 RUS86602.1 - 0.00023 21.4 0.1 0.00056 20.1 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS86602.1 - 0.00027 21.2 0.0 0.00084 19.6 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS86602.1 - 0.00048 20.6 0.0 0.0016 19.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS86602.1 - 0.00068 20.2 0.0 0.00092 19.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS86602.1 - 0.021 15.3 0.1 4 8.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 RUS86603.1 - 5.8e-28 97.3 6.4 2.5e-07 31.2 0.0 7.8 6 3 1 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86603.1 - 7e-20 71.1 1.0 0.00013 22.4 0.0 8.6 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS86603.1 - 9e-15 53.3 10.2 0.27 11.9 0.0 10.7 12 0 0 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 RUS86603.1 - 2.6e-14 53.1 6.5 9.7e-05 22.6 0.1 8.4 10 0 0 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS86603.1 - 5.5e-09 36.1 3.5 0.026 14.9 0.1 7.9 9 0 0 9 9 9 2 Ankyrin repeat RecX PF02631.16 RUS86604.1 - 1.4e-06 28.8 0.5 0.45 11.0 0.0 3.7 1 1 3 4 4 4 3 RecX family Ubiq_cyt_C_chap PF03981.12 RUS86604.1 - 4.7e-05 23.5 0.5 12 6.0 0.0 4.9 1 1 3 5 5 5 2 Ubiquinol-cytochrome C chaperone PanZ PF12568.8 RUS86604.1 - 0.0014 18.4 2.1 4.5 7.0 0.2 4.0 1 1 3 4 4 4 3 Acetyltransferase (GNAT) domain, PanZ DUF3367 PF11847.8 RUS86604.1 - 0.37 8.6 13.8 3.4 5.4 0.3 4.3 1 1 4 5 5 5 0 Alpha-(1->3)-arabinofuranosyltransferase Ank_3 PF13606.6 RUS86605.1 - 4.6e-05 23.5 3.8 3.9 8.4 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RUS86605.1 - 0.00083 19.9 0.4 0.34 11.5 0.2 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS86605.1 - 0.001 19.6 0.1 0.062 13.9 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS86605.1 - 0.16 12.3 0.4 62 4.1 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS86606.1 - 6e-29 100.5 0.1 1.4e-10 41.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86606.1 - 2e-21 76.1 6.1 2.6e-08 34.2 0.2 5.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS86606.1 - 6.7e-21 72.1 4.5 0.00018 21.7 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RUS86606.1 - 1.2e-19 69.8 5.6 8.2e-05 22.9 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 RUS86606.1 - 1.1e-13 51.2 4.4 5.3e-06 26.6 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Lectin_C PF00059.21 RUS86608.1 - 7.2e-08 33.1 0.8 7.2e-08 33.1 0.8 2.3 3 0 0 3 3 3 1 Lectin C-type domain HRM PF02793.22 RUS86608.1 - 0.034 14.4 9.7 0.027 14.8 5.0 2.6 2 0 0 2 2 2 0 Hormone receptor domain NOA36 PF06524.12 RUS86608.1 - 0.51 9.6 9.6 0.88 8.8 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 RUS86608.1 - 4 7.9 5.6 4.6 7.7 3.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_2 PF00002.24 RUS86609.1 - 2.7e-45 154.6 12.1 4.1e-45 154.0 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS86609.1 - 4e-12 46.5 1.9 4e-12 46.5 1.9 1.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF4692 PF15763.5 RUS86609.1 - 0.002 18.6 1.4 0.0032 18.0 1.4 1.3 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) Velvet PF11754.8 RUS86609.1 - 0.12 12.3 3.7 0.18 11.8 3.7 1.1 1 0 0 1 1 1 0 Velvet factor Androgen_recep PF02166.16 RUS86609.1 - 0.32 9.8 4.5 0.4 9.5 4.5 1.1 1 0 0 1 1 1 0 Androgen receptor FAM76 PF16046.5 RUS86609.1 - 0.67 9.3 6.8 1 8.6 6.8 1.2 1 0 0 1 1 1 0 FAM76 protein SelP_N PF04592.14 RUS86609.1 - 0.76 9.1 18.3 1.1 8.6 18.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 RUS86609.1 - 1 7.8 10.7 1.4 7.4 10.7 1.1 1 0 0 1 1 1 0 Macoilin family CrgA PF06781.12 RUS86609.1 - 3.8 7.6 4.6 1.1 9.4 0.3 2.3 2 0 0 2 2 2 0 Cell division protein CrgA Flagellin_N PF00669.20 RUS86610.1 - 0.16 12.1 6.0 2 8.5 2.0 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region CARD PF00619.21 RUS86611.1 - 5.4e-05 23.2 0.5 0.00011 22.1 0.5 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Trypsin_2 PF13365.6 RUS86612.1 - 1.9e-05 25.6 0.1 4.2e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain FG-GAP PF01839.23 RUS86613.1 - 2.2e-21 75.7 18.7 9.3e-08 32.1 6.0 4.7 4 0 0 4 4 4 3 FG-GAP repeat Zn_dep_PLPC PF00882.18 RUS86613.1 - 6.8e-18 65.3 3.1 1.4e-17 64.2 3.1 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 RUS86613.1 - 9.3e-06 26.1 5.4 0.00035 21.1 0.9 3.2 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SGL PF08450.12 RUS86614.1 - 2.6e-30 105.8 0.0 4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 RUS86614.1 - 0.0039 17.2 0.4 6.1 7.1 0.0 3.8 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.11 RUS86614.1 - 0.022 14.9 2.0 26 5.5 0.1 4.1 3 0 0 3 3 3 0 Two component regulator propeller SdiA-regulated PF06977.11 RUS86614.1 - 0.2 10.8 0.1 1.3 8.2 0.0 2.2 3 0 0 3 3 3 0 SdiA-regulated Peptidase_M48_N PF16491.5 RUS86614.1 - 0.22 11.4 1.4 0.3 11.0 1.4 1.2 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices NDUFA12 PF05071.16 RUS86615.1 - 1e-12 48.7 1.0 1.7e-12 48.0 0.8 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UspB PF10625.9 RUS86615.1 - 0.0058 16.6 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein B (UspB) BK_channel_a PF03493.18 RUS86615.1 - 0.059 13.6 0.5 0.13 12.4 0.5 1.7 1 1 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit HAUS-augmin3 PF14932.6 RUS86616.1 - 0.0016 18.0 1.8 0.0016 18.0 1.8 1.9 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 RUS86616.1 - 0.0053 16.7 0.9 0.0053 16.7 0.9 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF1640 PF07798.11 RUS86616.1 - 0.0082 16.2 8.8 0.015 15.3 8.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) GrpE PF01025.19 RUS86616.1 - 0.0092 15.7 2.8 0.02 14.6 2.4 1.8 1 1 0 1 1 1 1 GrpE Cep57_CLD_2 PF14197.6 RUS86616.1 - 0.011 15.7 1.1 0.011 15.7 1.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Suppressor_APC PF11414.8 RUS86616.1 - 0.014 15.4 2.6 0.044 13.9 2.6 2.0 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CCDC106 PF15794.5 RUS86616.1 - 0.015 15.0 2.3 0.024 14.4 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Exonuc_VII_L PF02601.15 RUS86616.1 - 0.036 13.6 1.5 0.039 13.5 1.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit STAG PF08514.11 RUS86616.1 - 0.036 14.0 3.0 0.041 13.8 0.3 2.4 2 1 1 3 3 3 0 STAG domain DUF4407 PF14362.6 RUS86616.1 - 0.042 13.2 0.9 0.061 12.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EST1 PF10374.9 RUS86616.1 - 0.052 14.2 1.3 0.091 13.4 1.2 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 BST2 PF16716.5 RUS86616.1 - 0.054 14.1 0.7 0.054 14.1 0.7 2.5 4 0 0 4 4 1 0 Bone marrow stromal antigen 2 CENP-Q PF13094.6 RUS86616.1 - 0.055 13.7 5.4 0.085 13.1 5.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PhoU_div PF01865.16 RUS86616.1 - 0.063 12.6 2.4 0.77 9.1 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF47 FAM76 PF16046.5 RUS86616.1 - 0.14 11.5 1.9 0.067 12.5 0.3 1.5 2 0 0 2 2 2 0 FAM76 protein GIT_CC PF16559.5 RUS86616.1 - 0.3 11.0 6.5 2.3 8.1 2.6 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 RUS86616.1 - 0.33 11.0 6.8 2.2 8.3 2.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 RUS86616.1 - 0.35 11.1 7.1 0.048 13.9 2.0 2.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 RUS86616.1 - 0.4 10.7 11.3 1.6 8.7 2.2 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DivIC PF04977.15 RUS86616.1 - 0.53 10.1 7.9 0.13 12.1 3.5 2.3 2 1 0 2 2 1 0 Septum formation initiator DUF4482 PF14818.6 RUS86616.1 - 0.68 10.8 6.0 1.2 10.0 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) SlyX PF04102.12 RUS86616.1 - 0.74 10.5 12.9 1.5 9.5 7.0 3.5 1 1 2 3 3 3 0 SlyX Fib_alpha PF08702.10 RUS86616.1 - 0.88 9.8 9.0 2.5 8.3 3.2 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 RUS86616.1 - 4.6 7.4 7.1 0.65 10.1 1.5 2.5 3 1 0 3 3 3 0 MbeD/MobD like GPS2_interact PF15784.5 RUS86616.1 - 5.7 7.4 10.5 24 5.4 0.2 3.2 1 1 2 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF4140 PF13600.6 RUS86616.1 - 6.1 7.4 6.1 1.4 9.4 0.4 2.6 3 1 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF737 PF05300.11 RUS86616.1 - 6.4 7.1 8.5 1.2 9.5 1.2 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF737) TolA_bind_tri PF16331.5 RUS86616.1 - 7.2 6.8 13.5 8.2 6.6 9.0 3.1 2 2 0 2 2 2 0 TolA binding protein trimerisation Pkinase_Tyr PF07714.17 RUS86617.1 - 1.6e-96 322.5 0.0 2.2e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS86617.1 - 2.3e-48 164.9 0.0 3.1e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 RUS86617.1 - 1.1e-25 89.5 0.2 2.9e-25 88.2 0.1 1.8 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 RUS86617.1 - 1.3e-18 66.4 0.5 4.1e-18 64.7 0.2 2.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 RUS86617.1 - 2.7e-12 46.3 0.1 1.4e-11 44.0 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RUS86617.1 - 5.6e-10 38.8 0.0 7.6e-09 35.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 RUS86617.1 - 9.9e-07 28.0 0.0 2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS86617.1 - 0.0039 17.2 0.0 0.17 11.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS86617.1 - 0.018 14.4 0.1 0.039 13.3 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.11 RUS86617.1 - 0.03 14.6 0.2 0.12 12.6 0.3 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain B2 PF11473.8 RUS86617.1 - 0.045 13.6 0.2 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 RNA binding protein B2 hSH3 PF14603.6 RUS86617.1 - 0.082 13.4 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain Lig_chan-Glu_bd PF10613.9 RUS86619.1 - 2.1e-19 69.8 0.5 4.2e-19 68.8 0.1 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 RUS86619.1 - 4.7e-13 49.2 0.0 3.1e-11 43.3 0.0 2.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS86619.1 - 1e-12 48.0 0.0 3.1e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 RUS86619.1 - 1.2e-07 31.2 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region CI-B14_5a PF07347.12 RUS86620.1 - 7.6e-29 99.4 0.1 8.8e-29 99.2 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) WD40 PF00400.32 RUS86621.1 - 8.9e-08 32.7 6.6 0.00071 20.3 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86621.1 - 1.4e-05 25.3 0.9 13 6.2 0.0 5.0 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 RUS86621.1 - 6.7e-05 22.0 0.2 0.00012 21.1 0.2 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain LEP503 PF15221.6 RUS86621.1 - 0.49 10.8 1.5 2.2 8.6 0.3 2.2 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 ELM2 PF01448.24 RUS86622.1 - 1.4e-07 32.2 0.1 7.8e-07 29.7 0.1 2.4 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 RUS86622.1 - 0.001 19.2 0.3 0.0022 18.2 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain EGF PF00008.27 RUS86625.1 - 1.8e-07 31.3 31.3 0.00014 22.1 2.4 4.2 3 2 1 4 4 4 3 EGF-like domain cEGF PF12662.7 RUS86625.1 - 3e-05 23.8 21.0 0.0001 22.2 0.6 3.8 3 1 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS86625.1 - 9.2e-05 22.6 31.3 0.00013 22.1 9.3 3.5 2 1 1 3 3 3 2 Coagulation Factor Xa inhibitory site CSN8_PSD8_EIF3K PF10075.9 RUS86625.1 - 0.019 15.0 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family EGF_2 PF07974.13 RUS86625.1 - 0.034 14.5 8.2 0.034 14.5 8.2 3.7 3 1 0 3 3 3 0 EGF-like domain zf-C2H2 PF00096.26 RUS86626.1 - 2.8e-08 33.8 18.1 6.3e-05 23.2 1.4 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS86626.1 - 1e-07 32.0 17.3 7.1e-05 23.1 0.2 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS86626.1 - 3.5e-07 30.5 15.8 0.0012 19.5 1.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger PyrI_C PF02748.15 RUS86626.1 - 0.0027 17.6 5.7 0.23 11.4 0.0 3.3 3 0 0 3 3 3 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 RUS86626.1 - 0.021 14.6 2.7 1.5 8.6 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS86626.1 - 0.023 15.0 0.4 0.023 15.0 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 RUS86626.1 - 0.026 14.6 11.9 0.59 10.2 0.4 3.4 2 1 1 3 3 3 0 BED zinc finger SET PF00856.28 RUS86626.1 - 0.034 14.5 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 SET domain zf-C2H2_2 PF12756.7 RUS86626.1 - 0.12 12.7 3.7 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RUS86626.1 - 1.5 9.3 12.6 2 8.9 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RUS86626.1 - 2.5 8.6 9.0 3.6 8.1 0.0 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 RUS86626.1 - 7.7 6.4 11.9 0.21 11.4 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EB PF01683.18 RUS86627.1 - 0.00097 19.4 6.8 0.00097 19.4 6.8 3.0 2 1 1 3 3 3 2 EB module Plasmod_Pvs28 PF06247.11 RUS86627.1 - 0.0031 17.8 7.8 0.079 13.3 0.6 3.2 2 1 0 2 2 2 2 Pvs28 EGF domain Pyridox_oxase_2 PF12766.7 RUS86628.1 - 0.11 13.2 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase CBM_14 PF01607.24 RUS86629.1 - 1.5e-27 95.5 159.4 0.38 10.9 0.6 26.1 10 9 11 21 21 21 21 Chitin binding Peritrophin-A domain DUF459 PF04311.13 RUS86629.1 - 0.0082 15.2 10.7 6.3 5.7 0.1 5.2 1 1 5 6 6 6 4 Protein of unknown function (DUF459) 7tm_1 PF00001.21 RUS86630.1 - 2.2e-08 33.7 19.9 2.7e-08 33.5 19.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS86630.1 - 0.0001 21.7 20.9 0.00053 19.4 20.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw BEN PF10523.9 RUS86630.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 BEN domain Homeobox_KN PF05920.11 RUS86631.1 - 8.9e-16 57.5 0.3 8.9e-16 57.5 0.3 2.2 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 RUS86631.1 - 3.1e-07 30.1 2.0 4.7e-07 29.6 2.0 1.3 1 0 0 1 1 1 1 Homeodomain CNDH2_C PF16858.5 RUS86631.1 - 0.013 15.4 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 RUS86631.1 - 0.17 9.9 2.3 0.23 9.5 2.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RUS86631.1 - 0.2 11.0 1.0 0.3 10.4 1.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 RUS86631.1 - 0.62 8.3 4.3 0.86 7.8 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein A_deaminase PF00962.22 RUS86632.1 - 3.6e-22 79.1 0.0 5.1e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 RUS86632.1 - 3.8e-17 62.4 0.0 1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal zf-C2H2 PF00096.26 RUS86635.1 - 1.2e-22 79.1 37.2 4.6e-06 26.8 1.5 6.0 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86635.1 - 4.8e-19 67.4 29.7 0.00016 22.2 0.7 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS86635.1 - 1.5e-16 59.9 32.3 8.4e-07 29.2 0.5 6.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS86635.1 - 1.2e-10 41.3 8.1 0.0022 18.2 0.2 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS86635.1 - 3.2e-08 33.4 27.6 0.0031 17.5 0.4 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 RUS86635.1 - 9.5e-07 29.0 15.2 0.0081 16.5 0.3 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS86635.1 - 6.9e-05 22.9 19.2 0.12 12.5 0.1 4.8 4 0 0 4 4 4 2 Zinc ribbon domain zf-C2HE PF16278.5 RUS86635.1 - 0.0021 18.4 24.9 0.044 14.2 0.2 4.7 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 RUS86635.1 - 0.01 15.6 32.3 0.3 10.9 0.6 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RUS86635.1 - 0.13 13.0 0.4 0.13 13.0 0.4 3.4 2 1 1 3 3 2 0 zinc-ribbon family zf-Di19 PF05605.12 RUS86635.1 - 0.29 11.4 16.3 0.082 13.2 1.0 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4764 PF15961.5 RUS86635.1 - 0.58 8.8 10.0 3 6.4 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) XPA_N PF01286.18 RUS86635.1 - 0.61 10.2 14.8 13 6.0 0.5 4.9 5 0 0 5 5 5 0 XPA protein N-terminal zf-C2HC_2 PF13913.6 RUS86635.1 - 0.79 9.7 20.3 1.9 8.5 0.2 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type HypA PF01155.19 RUS86635.1 - 0.89 9.6 15.5 4.6 7.3 2.3 3.7 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 RUS86635.1 - 1 9.4 13.4 17 5.5 4.1 4.1 3 2 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 RUS86635.1 - 4.2 7.8 17.8 7.2 7.0 1.1 4.6 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 RUS86635.1 - 4.7 6.9 18.9 9.1 6.0 0.1 5.2 4 1 1 5 5 5 0 Ubiquitin-Binding Zinc Finger Nop14 PF04147.12 RUS86636.1 - 8.1e-05 21.1 27.9 8.7e-05 21.0 27.9 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS86636.1 - 0.0038 16.7 34.8 0.0043 16.5 34.8 1.1 1 0 0 1 1 1 1 SDA1 eIF-3c_N PF05470.12 RUS86636.1 - 0.15 10.3 16.2 0.19 10.0 16.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.12 RUS86636.1 - 1.3 7.4 30.8 1.5 7.2 30.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Kringle PF00051.18 RUS86637.1 - 1.5e-13 50.9 2.8 1.2e-05 25.5 1.8 2.7 2 0 0 2 2 2 2 Kringle domain Sushi PF00084.20 RUS86637.1 - 1 10.0 6.5 2.1 9.0 0.9 3.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Cyt-b5 PF00173.28 RUS86638.1 - 5.5e-21 74.5 0.0 1.1e-20 73.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.29 RUS86639.1 - 4e-31 108.2 0.0 1.3e-30 106.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS86639.1 - 4.3e-07 30.3 0.5 3.8e-06 27.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RUS86639.1 - 4.4e-07 30.5 0.0 3.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS86639.1 - 3.8e-06 27.4 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 RUS86639.1 - 5.7e-05 23.2 0.0 0.00025 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS86639.1 - 0.00025 21.3 0.1 0.0078 16.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS86639.1 - 0.0003 21.0 0.0 0.0012 19.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS86639.1 - 0.00094 19.1 0.3 0.0061 16.5 0.3 2.2 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 RUS86639.1 - 0.001 19.5 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 RUS86639.1 - 0.0012 18.9 0.0 0.0049 16.9 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 RUS86639.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 RUS86639.1 - 0.0017 17.8 0.1 0.75 9.1 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_11 PF13086.6 RUS86639.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RUS86639.1 - 0.0019 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_25 PF13481.6 RUS86639.1 - 0.002 17.8 0.1 0.21 11.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS86639.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS86639.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RUS86639.1 - 0.003 17.7 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 RUS86639.1 - 0.0031 17.3 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 RUS86639.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 RUS86639.1 - 0.0063 16.5 0.1 3.9 7.3 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 RUS86639.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 RUS86639.1 - 0.0076 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 RUS86639.1 - 0.0077 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 RUS86639.1 - 0.0081 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 RUS86639.1 - 0.01 15.0 0.0 0.035 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 RUS86639.1 - 0.015 15.7 0.0 0.057 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RUS86639.1 - 0.02 15.2 0.3 0.14 12.5 0.0 2.5 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 RUS86639.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 RUS86639.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.11 RUS86639.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 RUS86639.1 - 0.048 12.9 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 RUS86639.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 RUS86639.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.21 RUS86639.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 RUS86639.1 - 0.075 12.4 0.0 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 RUS86639.1 - 0.086 12.1 0.1 1.8 7.7 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.16 RUS86639.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 RUS86639.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 RUS86639.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family Snf7 PF03357.21 RUS86640.1 - 7.1e-43 146.2 8.5 7.1e-43 146.2 8.5 1.3 2 0 0 2 2 2 1 Snf7 EDR1 PF14381.6 RUS86640.1 - 0.041 13.6 0.2 0.06 13.1 0.2 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 RGS_DHEX PF18148.1 RUS86640.1 - 0.12 12.5 2.5 0.19 11.8 0.2 2.3 2 1 0 2 2 2 0 Regulator of G-protein signalling DHEX domain V_ATPase_I PF01496.19 RUS86640.1 - 0.26 9.1 3.7 0.31 8.9 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 5_3_exonuc PF01367.20 RUS86640.1 - 0.97 10.1 6.6 1.3 9.7 1.7 2.9 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Laminin_II PF06009.12 RUS86640.1 - 7.7 6.5 11.2 2.8 7.9 4.5 2.3 1 1 1 2 2 2 0 Laminin Domain II Snf7 PF03357.21 RUS86641.1 - 3.4e-53 179.8 12.7 3.4e-53 179.8 12.7 1.6 2 0 0 2 2 2 1 Snf7 SYF2 PF08231.12 RUS86641.1 - 0.00082 19.8 4.0 0.0013 19.2 4.0 1.3 1 0 0 1 1 1 1 SYF2 splicing factor V_ATPase_I PF01496.19 RUS86641.1 - 0.028 12.4 6.1 0.033 12.1 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.11 RUS86641.1 - 1.6 8.2 4.7 28 4.1 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein 7tm_1 PF00001.21 RUS86642.1 - 3.2e-28 98.8 18.1 1.8e-27 96.4 18.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS86642.1 - 7.1e-05 22.7 8.6 0.0048 16.7 2.6 2.2 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS86642.1 - 0.00012 21.5 4.8 0.00012 21.5 4.8 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS86642.1 - 0.00015 21.2 0.4 0.00015 21.2 0.4 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw CDC45 PF02724.14 RUS86642.1 - 0.00039 18.9 7.6 0.00048 18.6 7.6 1.1 1 0 0 1 1 1 1 CDC45-like protein SID-1_RNA_chan PF13965.6 RUS86642.1 - 0.0031 16.0 0.5 0.0031 16.0 0.5 1.9 3 0 0 3 3 3 1 dsRNA-gated channel SID-1 GREB1 PF15782.5 RUS86642.1 - 0.0064 13.7 15.8 0.0079 13.4 15.8 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer DDHD PF02862.17 RUS86642.1 - 0.0078 16.4 7.2 0.012 15.8 7.2 1.4 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 RUS86642.1 - 0.03 14.3 43.0 0.041 13.9 43.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 RUS86642.1 - 0.031 13.4 15.7 0.041 13.0 15.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sec62 PF03839.16 RUS86642.1 - 0.14 11.7 8.1 0.29 10.6 8.1 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 RUS86642.1 - 0.24 11.2 21.5 0.36 10.6 21.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 RUS86642.1 - 0.29 10.9 12.8 1.1 9.0 10.0 2.5 2 0 0 2 2 2 0 Connexin Lin-8 PF03353.15 RUS86642.1 - 0.33 10.5 23.3 0.47 10.0 23.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDK5_activator PF03261.15 RUS86642.1 - 0.34 10.4 12.7 0.46 10.0 12.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Tim54 PF11711.8 RUS86642.1 - 0.43 9.3 16.3 0.76 8.5 16.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CCSAP PF15748.5 RUS86642.1 - 0.6 10.2 25.9 0.87 9.7 25.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4746 PF15928.5 RUS86642.1 - 0.6 9.5 14.7 0.88 8.9 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3292 PF11696.8 RUS86642.1 - 0.61 8.4 13.3 0.91 7.8 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MMR1 PF08505.10 RUS86642.1 - 1.2 9.4 25.8 1.9 8.7 25.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Plasmodium_Vir PF05795.11 RUS86642.1 - 1.2 8.4 8.7 1.7 8.0 8.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Proton_antipo_C PF01010.19 RUS86642.1 - 1.4 8.5 7.8 1.8 8.2 3.4 2.4 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus PepSY_TM PF03929.16 RUS86642.1 - 1.5 8.5 13.5 0.1 12.2 6.4 2.5 2 1 0 2 2 2 0 PepSY-associated TM region GET2 PF08690.10 RUS86642.1 - 1.7 8.2 20.8 0.056 13.1 14.5 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 PAT1 PF09770.9 RUS86642.1 - 3.6 5.7 40.5 4.9 5.3 40.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YABBY PF04690.13 RUS86642.1 - 4.3 7.9 14.1 8.7 6.9 14.1 1.5 1 0 0 1 1 1 0 YABBY protein PA26 PF04636.13 RUS86642.1 - 4.5 6.1 15.3 6.4 5.6 15.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TCP PF03634.13 RUS86642.1 - 5.2 7.6 21.4 9.3 6.8 21.4 1.4 1 0 0 1 1 1 0 TCP family transcription factor eIF3_subunit PF08597.10 RUS86642.1 - 5.6 6.8 21.9 8.5 6.2 21.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hamartin PF04388.12 RUS86642.1 - 6.6 5.3 22.0 8.5 4.9 22.0 1.1 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 RUS86642.1 - 7.2 6.6 15.7 12 5.8 15.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.12 RUS86642.1 - 7.5 5.4 25.1 10 5.0 25.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Endostatin PF06482.11 RUS86642.1 - 7.7 5.9 23.3 12 5.2 23.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Bul1_N PF04425.12 RUS86642.1 - 7.8 5.1 19.6 11 4.6 19.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus RNase_H PF00075.24 RUS86643.1 - 6e-15 55.7 0.0 1.6e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS86643.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like SDA1 PF05285.12 RUS86644.1 - 0.0042 16.6 23.8 0.0057 16.1 23.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS86644.1 - 0.045 12.0 29.2 0.062 11.5 29.2 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 RUS86644.1 - 0.18 11.0 11.6 0.28 10.4 11.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RUS86644.1 - 0.3 9.1 47.3 0.42 8.7 47.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RUS86644.1 - 0.82 8.4 3.9 1.1 7.9 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 RUS86644.1 - 3 6.3 28.3 4.4 5.7 28.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.22 RUS86645.1 - 1.4e-20 73.5 0.1 4.4e-20 71.9 0.1 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS86645.1 - 0.0022 18.2 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 RUS86645.1 - 0.0061 16.1 0.1 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS86645.1 - 0.012 15.6 0.3 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 RUS86645.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF4587 PF15248.6 RUS86646.1 - 2.6 8.9 7.8 9.3 7.1 7.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4587) LIM PF00412.22 RUS86647.1 - 1.5e-31 108.4 40.0 4.5e-12 46.0 9.2 3.7 3 0 0 3 3 3 3 LIM domain DUF4587 PF15248.6 RUS86647.1 - 2.9 8.7 6.5 27 5.6 6.5 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) DAO PF01266.24 RUS86649.1 - 1.6e-10 41.1 0.0 1.7e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS86649.1 - 7.1e-05 22.2 0.1 9.1e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS86649.1 - 0.00017 20.8 0.1 0.00018 20.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS86649.1 - 0.00034 19.9 0.0 0.00041 19.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS86649.1 - 0.0022 16.8 0.0 0.0023 16.7 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 RUS86649.1 - 0.0076 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 RUS86649.1 - 0.017 14.8 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 RUS86649.1 - 0.024 13.8 0.3 0.032 13.3 0.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 RUS86649.1 - 0.033 14.7 0.1 0.059 13.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RUS86649.1 - 0.043 14.3 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Ldh_1_N PF00056.23 RUS86649.1 - 0.074 13.1 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 RUS86649.1 - 0.075 12.3 0.2 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RUS86649.1 - 0.14 11.0 0.6 0.22 10.3 0.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 RUS86650.1 - 1.6e-16 60.8 0.0 1.8e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 RUS86651.1 - 3.3e-37 128.9 0.0 3.8e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS86651.1 - 4.7e-06 26.0 0.1 7.2e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS86651.1 - 0.00012 21.3 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS86651.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS86651.1 - 0.018 15.3 0.4 0.057 13.7 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RUS86651.1 - 0.05 12.3 0.7 0.071 11.8 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 RUS86651.1 - 0.063 12.3 0.5 0.095 11.7 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 RUS86651.1 - 0.11 11.5 0.4 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A OMP_b-brl PF13505.6 RUS86651.1 - 0.16 12.1 0.6 0.31 11.1 0.6 1.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain NAD_binding_7 PF13241.6 RUS86651.1 - 0.16 12.4 0.1 0.24 11.9 0.1 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 RUS86651.1 - 0.21 12.2 0.2 0.56 10.8 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transglut_N PF00868.20 RUS86652.1 - 1.8e-31 108.9 0.0 5.2e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 RUS86652.1 - 1e-19 70.6 0.1 1.5e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 RUS86652.1 - 3e-17 63.1 1.8 1.3e-16 61.0 2.1 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily NPCBM_assoc PF10633.9 RUS86652.1 - 0.17 12.2 0.7 0.93 9.8 0.7 2.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Methyltransf_11 PF08241.12 RUS86653.1 - 3.3e-12 46.9 0.0 5.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS86653.1 - 4.3e-12 46.6 0.0 8.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS86653.1 - 6.2e-12 45.7 0.0 7.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS86653.1 - 1.7e-09 37.7 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS86653.1 - 1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS86653.1 - 3e-07 31.1 0.0 5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 RUS86653.1 - 3.2e-07 30.1 0.0 4e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 RUS86653.1 - 4.8e-06 26.6 0.0 1.3e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 RUS86653.1 - 0.00058 19.0 0.0 0.0007 18.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 RUS86653.1 - 0.0042 16.6 0.0 0.0097 15.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 RUS86653.1 - 0.0062 16.2 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 RUS86653.1 - 0.015 13.9 0.0 0.024 13.2 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 RUS86653.1 - 0.019 13.9 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 RUS86653.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FA_synthesis PF02504.15 RUS86653.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein CMAS PF02353.20 RUS86653.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Herpes_UL43 PF05072.13 RUS86654.1 - 0.09 11.9 0.7 0.11 11.6 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Granulin PF00396.18 RUS86655.1 - 2.8e-195 632.5 493.8 1.1e-15 57.6 22.6 25.6 25 3 3 28 28 28 20 Granulin GSIII_N PF12437.8 RUS86655.1 - 0.38 10.4 3.8 1.9e+02 1.6 0.0 5.4 7 0 0 7 7 7 0 Glutamine synthetase type III N terminal CLZ PF16526.5 RUS86656.1 - 0.14 12.5 4.5 0.49 10.8 1.1 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-RRN7 PF11781.8 RUS86657.1 - 3.1e-08 33.2 3.6 5.8e-08 32.3 3.6 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 RUS86657.1 - 7.4e-06 25.4 2.7 1.5e-05 24.4 2.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RPA_interact_C PF14768.6 RUS86657.1 - 0.16 12.6 0.5 0.54 10.9 0.5 1.9 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Prok-RING_1 PF14446.6 RUS86657.1 - 0.21 11.6 1.1 0.49 10.4 1.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 RUS86657.1 - 0.24 11.1 3.2 0.58 9.9 3.2 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS91 PF14319.6 RUS86657.1 - 0.5 10.4 2.5 2.5 8.2 0.7 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DZR PF12773.7 RUS86657.1 - 0.56 10.3 2.8 1.4 9.0 2.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon DpnI PF06044.12 RUS86657.1 - 0.64 9.6 3.5 14 5.3 0.0 3.1 4 0 0 4 4 4 0 Dam-replacing family Ephrin_rec_like PF07699.13 RUS86657.1 - 1.3 8.8 6.6 2.3 8.1 5.6 1.9 1 1 1 2 2 2 0 Putative ephrin-receptor like DUF2318 PF10080.9 RUS86657.1 - 1.3 9.1 4.2 2.8 8.1 4.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Lipase_GDSL PF00657.22 RUS86658.1 - 3.5e-15 56.5 0.0 6.7e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RUS86658.1 - 8.5e-09 36.1 0.7 2.1e-08 34.8 0.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Anoctamin PF04547.12 RUS86659.1 - 3.9e-157 523.7 15.7 5.1e-157 523.3 15.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RUS86659.1 - 2.9e-62 210.4 1.3 4.6e-62 209.7 1.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Abhydrolase_1 PF00561.20 RUS86661.1 - 1e-21 77.8 0.3 1.8e-20 73.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 RUS86661.1 - 8.2e-19 66.9 0.1 2e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 RUS86661.1 - 2.7e-08 33.4 0.0 3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RUS86661.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3089 PF11288.8 RUS86661.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) FSH1 PF03959.13 RUS86661.1 - 0.099 12.3 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Kinesin PF00225.23 RUS86662.1 - 1.9e-86 290.0 0.1 1.7e-48 165.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 RUS86662.1 - 6.1e-39 133.3 0.0 1.4e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding betaPIX_CC PF16523.5 RUS86662.1 - 0.026 14.3 0.5 0.026 14.3 0.5 2.3 3 0 0 3 3 3 0 betaPIX coiled coil NPV_P10 PF05531.12 RUS86662.1 - 0.038 14.4 0.6 0.038 14.4 0.6 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_22 PF13401.6 RUS86662.1 - 0.065 13.5 0.4 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 RUS86662.1 - 1.3 7.9 5.2 0.2 10.5 0.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein CREPT PF16566.5 RUS86662.1 - 1.9 8.7 5.9 0.63 10.2 0.4 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour YscO PF07321.12 RUS86662.1 - 2.6 8.0 9.9 0.072 13.1 1.7 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Methyltransf_25 PF13649.6 RUS86663.1 - 6.3e-13 49.2 0.1 2.5e-12 47.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS86663.1 - 2.1e-10 41.1 0.0 6.4e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RUS86663.1 - 3.3e-10 39.8 0.0 5.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RUS86663.1 - 6.1e-09 35.8 0.1 1.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS86663.1 - 6.4e-08 32.6 0.1 2.1e-06 27.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS86663.1 - 1.9e-07 30.8 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 RUS86663.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 RUS86663.1 - 4.6e-05 22.9 0.0 9.5e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS86663.1 - 7.8e-05 23.3 0.0 0.00058 20.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 RUS86663.1 - 8.5e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 RUS86663.1 - 0.00052 20.0 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 RUS86663.1 - 0.0023 18.1 0.2 0.0053 16.9 0.2 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 RUS86663.1 - 0.0024 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 RUS86663.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 RUS86663.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 RUS86663.1 - 0.0094 15.3 0.1 0.03 13.6 0.0 1.8 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_32 PF13679.6 RUS86663.1 - 0.017 15.1 0.1 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 RUS86663.1 - 0.033 14.1 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 PRMT5 oligomerisation domain RrnaAD PF00398.20 RUS86663.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 RUS86663.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 RUS86663.1 - 0.12 13.5 0.0 0.26 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 RUS86663.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CRAL_TRIO_2 PF13716.6 RUS86665.1 - 4.1e-33 114.5 1.4 7.1e-33 113.7 1.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 RUS86665.1 - 4.4e-18 65.4 0.1 1.2e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.20 RUS86665.1 - 7.8e-10 38.7 0.3 1.6e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DNA_pol3_finger PF17657.1 RUS86665.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain CSTF2_hinge PF14327.6 RUS86666.1 - 1.7e-31 108.5 5.6 4.5e-31 107.1 5.6 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 RUS86666.1 - 2e-24 85.2 0.0 3.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 RUS86666.1 - 1.4e-18 66.2 9.6 4.3e-18 64.6 6.8 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 RUS86666.1 - 0.0055 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF908 PF06012.12 RUS86666.1 - 0.035 13.5 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF4797 PF16051.5 RUS86666.1 - 0.052 13.5 3.7 0.13 12.2 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) RRM_occluded PF16842.5 RUS86666.1 - 0.092 12.6 0.0 0.35 10.8 0.0 1.9 2 1 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RUS86666.1 - 0.093 13.0 0.0 4.1 7.6 0.0 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ank_2 PF12796.7 RUS86667.1 - 1.8e-27 95.7 0.1 1.4e-14 54.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS86667.1 - 5.6e-23 80.3 0.8 3.7e-07 30.3 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS86667.1 - 2.4e-20 72.3 1.4 1.9e-07 31.2 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS86667.1 - 4.4e-18 65.4 0.3 4.5e-07 30.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS86667.1 - 1.2e-17 62.1 0.6 0.0054 17.1 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat SAM_1 PF00536.30 RUS86667.1 - 4e-13 49.6 0.1 1.2e-12 48.0 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS86667.1 - 1.2e-10 41.3 0.1 3.5e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Tropomyosin_1 PF12718.7 RUS86667.1 - 0.68 10.1 0.0 0.68 10.1 0.0 2.4 2 0 0 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.19 RUS86667.1 - 0.85 7.5 3.1 1.2 7.0 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T-box PF00907.22 RUS86668.1 - 2.8e-58 197.2 0.0 6.4e-58 196.0 0.0 1.6 1 0 0 1 1 1 1 T-box MFS_1 PF07690.16 RUS86669.1 - 5.7e-10 38.7 32.0 0.00016 20.7 11.8 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS86669.1 - 0.00026 19.7 6.2 0.00026 19.7 6.2 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Ank_5 PF13857.6 RUS86670.1 - 1.6e-37 127.0 9.9 3.2e-08 33.7 0.1 8.5 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS86670.1 - 3.2e-34 116.8 2.9 2.6e-08 34.3 0.0 8.0 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS86670.1 - 1.1e-32 112.4 2.6 2.4e-07 31.3 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 RUS86670.1 - 1.3e-30 104.5 10.4 7.5e-05 23.0 0.0 9.1 10 1 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 RUS86670.1 - 1.4e-26 89.6 1.1 0.0007 19.9 0.0 10.0 11 0 0 11 11 11 5 Ankyrin repeat HEM4 PF02602.15 RUS86670.1 - 0.0049 16.3 0.0 0.58 9.5 0.0 2.8 3 0 0 3 3 3 1 Uroporphyrinogen-III synthase HemD RNA_pol_L_2 PF13656.6 RUS86673.1 - 1.2e-28 98.6 0.1 1.7e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RUS86673.1 - 4.8e-13 48.3 0.0 6.6e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyoxalase_5 PF14696.6 RUS86673.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal INCENP_N PF12178.8 RUS86676.1 - 0.015 15.3 6.8 65 3.6 0.0 6.6 8 0 0 8 8 8 0 Chromosome passenger complex (CPC) protein INCENP N terminal GBS_Bsp-like PF08481.10 RUS86676.1 - 0.098 12.8 4.3 98 3.2 0.0 4.5 1 1 2 4 4 4 0 GBS Bsp-like repeat SEA PF01390.20 RUS86681.1 - 1.3e-17 63.8 6.3 6.7e-14 51.9 0.1 4.4 2 1 2 4 4 4 2 SEA domain NUC130_3NT PF08158.12 RUS86681.1 - 1.7e-05 25.0 9.4 77 3.7 0.0 9.2 3 1 10 13 13 13 0 NUC130/3NT domain Asp23 PF03780.13 RUS86681.1 - 0.015 15.8 5.1 1.6 9.1 0.3 3.7 2 1 1 3 3 3 0 Asp23 family, cell envelope-related function PhaP_Bmeg PF09602.10 RUS86681.1 - 0.016 15.1 6.9 7.7 6.4 5.2 4.7 1 1 3 5 5 5 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MHCassoc_trimer PF08831.10 RUS86681.1 - 0.022 14.7 28.7 13 5.9 0.2 10.8 4 2 9 13 13 13 0 Class II MHC-associated invariant chain trimerisation domain DUF1548 PF07579.11 RUS86681.1 - 0.42 11.0 8.1 52 4.2 0.1 4.9 1 1 6 7 7 7 0 Domain of Unknown Function (DUF1548) Carbpep_Y_N PF05388.11 RUS86681.1 - 1.2 9.6 37.2 0.29 11.7 2.3 7.2 1 1 4 5 5 5 0 Carboxypeptidase Y pro-peptide GIT1_C PF12205.8 RUS86681.1 - 1.6 8.9 7.1 6.5 6.9 3.3 3.5 1 1 1 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term HD_2 PF12917.7 RUS86681.1 - 2.6 7.8 17.1 4.4 7.0 0.6 5.1 1 1 5 6 6 6 0 HD containing hydrolase-like enzyme DUF3091 PF11291.8 RUS86681.1 - 5.1 7.3 12.9 9.3 6.5 0.1 4.9 2 2 1 3 3 3 0 Protein of unknown function (DUF3091) XendoU PF09412.10 RUS86682.1 - 2.9e-41 141.4 0.1 2.9e-41 141.4 0.1 1.9 2 0 0 2 2 1 1 Endoribonuclease XendoU SEA PF01390.20 RUS86682.1 - 4.5e-13 49.2 0.0 9.4e-05 22.5 0.0 3.8 3 0 0 3 3 3 2 SEA domain AP3D1 PF06375.11 RUS86682.1 - 0.0012 19.1 18.7 0.0037 17.5 18.7 1.8 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 BRF1 PF07741.13 RUS86682.1 - 0.0068 16.7 10.4 0.0068 16.7 10.4 2.0 2 0 0 2 2 1 1 Brf1-like TBP-binding domain Rtf2 PF04641.12 RUS86682.1 - 0.0073 15.7 11.2 0.021 14.2 11.2 1.7 1 0 0 1 1 1 1 Rtf2 RING-finger RNA_polI_A34 PF08208.11 RUS86682.1 - 0.0083 16.2 21.5 0.018 15.2 21.5 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ORC5_C PF14630.6 RUS86682.1 - 0.0097 15.5 3.1 0.21 11.1 2.2 2.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Peptidase_S49_N PF08496.10 RUS86682.1 - 0.028 14.5 13.3 0.053 13.6 13.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 RUS86682.1 - 0.053 13.3 6.9 0.11 12.2 6.9 1.4 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 RUS86682.1 - 0.1 12.7 6.9 0.32 11.1 6.9 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein LicD PF04991.13 RUS86682.1 - 0.15 12.2 8.0 2.6 8.1 6.8 2.4 2 0 0 2 2 2 0 LicD family eIF3_subunit PF08597.10 RUS86682.1 - 0.58 10.0 21.5 0.38 10.6 19.4 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 RUS86682.1 - 0.6 8.3 7.7 0.93 7.7 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.10 RUS86682.1 - 1.7 9.6 18.6 6.2 7.8 18.6 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.9 RUS86682.1 - 2.5 7.6 35.0 5.3 6.6 35.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ORC_WH_C PF18137.1 RUS86682.1 - 2.8 8.0 9.7 7.7 6.6 9.7 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Sec62 PF03839.16 RUS86682.1 - 3.4 7.1 14.5 8.2 5.9 14.5 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3464 PF11947.8 RUS86682.1 - 6.8 6.4 16.2 19 5.0 16.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PPR PF01535.20 RUS86684.1 - 0.11 12.8 12.1 33 5.0 0.1 6.4 3 1 6 9 9 9 0 PPR repeat Clathrin PF00637.20 RUS86684.1 - 0.28 11.1 7.6 19 5.1 0.1 3.7 1 1 3 4 4 4 0 Region in Clathrin and VPS PPR_2 PF13041.6 RUS86684.1 - 0.45 10.7 7.5 54 4.1 0.1 4.8 2 1 4 6 6 6 0 PPR repeat family LPMO_10 PF03067.15 RUS86685.1 - 1.9e-30 107.0 0.3 2.5e-30 106.6 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TMEM141 PF15110.6 RUS86686.1 - 5.2e-05 23.7 0.4 73 4.0 0.0 5.8 2 1 9 11 11 11 0 TMEM141 protein family Keratin_B2_2 PF13885.6 RUS86686.1 - 0.0011 18.9 12.1 17 5.5 4.3 4.8 1 1 1 2 2 2 1 Keratin, high sulfur B2 protein Las1 PF04031.13 RUS86686.1 - 0.039 14.1 2.5 84 3.3 0.0 4.5 1 1 3 5 5 5 0 Las1-like Keratin_B2 PF01500.17 RUS86686.1 - 0.049 13.6 15.8 0.45 10.5 15.8 2.1 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein NUC173 PF08161.12 RUS86686.1 - 0.097 12.3 0.0 21 4.7 0.0 3.5 1 1 2 3 3 3 0 NUC173 domain Pyr_redox_dim PF02852.22 RUS86686.1 - 0.17 12.2 6.6 55 4.1 0.1 5.1 2 1 5 7 7 7 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyco_hydro_38C PF07748.13 RUS86687.1 - 3.3e-12 46.9 0.0 3e-05 24.2 0.0 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 RUS86688.1 - 1.3e-37 129.7 0.0 1.5e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 RUS86688.1 - 9.1e-06 25.7 0.1 1.9e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Snapin_Pallidin PF14712.6 RUS86690.1 - 7.3e-22 77.6 2.1 1.2e-21 76.9 2.1 1.3 1 0 0 1 1 1 1 Snapin/Pallidin GrpE PF01025.19 RUS86690.1 - 0.1 12.2 4.3 0.18 11.4 4.3 1.5 1 0 0 1 1 1 0 GrpE Sds3 PF08598.11 RUS86690.1 - 0.88 9.5 10.0 3.6 7.5 6.9 2.1 2 0 0 2 2 2 0 Sds3-like TCP PF03634.13 RUS86690.1 - 1.7 9.2 10.9 0.1 13.2 4.9 1.8 2 0 0 2 2 2 0 TCP family transcription factor DUF2390 PF09523.10 RUS86690.1 - 8.4 6.8 10.3 15 5.9 10.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2390) AAA_23 PF13476.6 RUS86691.1 - 0.0038 17.7 21.6 0.0038 17.7 21.6 2.7 3 0 0 3 3 3 1 AAA domain Ureide_permease PF07168.11 RUS86691.1 - 0.23 10.2 2.2 0.52 9.0 2.2 1.5 1 0 0 1 1 1 0 Ureide permease NEMP PF10225.9 RUS86691.1 - 0.4 10.3 7.3 1 8.9 7.3 1.6 1 0 0 1 1 1 0 NEMP family Lectin_C PF00059.21 RUS86692.1 - 5.5e-07 30.3 0.1 1.3e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain DUF366 PF04017.12 RUS86692.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF366) RIBIOP_C PF04950.12 RUS86694.1 - 0.032 13.6 0.0 51 3.2 0.0 3.6 1 1 3 4 4 4 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal LapA_dom PF06305.11 RUS86695.1 - 0.00053 19.7 0.6 0.00082 19.1 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DPM3 PF08285.11 RUS86695.1 - 0.053 13.7 0.0 0.053 13.7 0.0 1.0 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1361 PF07099.11 RUS86695.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) TFIIE_beta PF02186.15 RUS86696.1 - 6.1e-15 55.3 0.0 1.7e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 RUS86696.1 - 9.7e-09 34.8 0.1 2.2e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 DP PF08781.10 RUS86696.1 - 0.012 15.5 0.8 0.67 9.8 0.0 2.3 1 1 1 2 2 2 0 Transcription factor DP PhoQ_Sensor PF08918.10 RUS86696.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor TCR_zetazeta PF11628.8 RUS86698.1 - 8 6.2 6.8 0.99 9.1 0.5 2.5 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain DUF4573 PF15140.6 RUS86699.1 - 1e-07 31.9 3.7 0.63 9.8 0.1 4.4 1 1 5 6 6 6 6 Domain of unknown function (DUF4573) CppA_C PF14507.6 RUS86699.1 - 0.00076 20.2 32.2 48 4.8 0.2 9.9 1 1 11 12 12 12 0 CppA C-terminal Tox-URI2 PF15653.6 RUS86699.1 - 0.001 19.3 40.6 21 5.5 1.1 9.8 1 1 10 11 11 11 0 URI fold toxin 2 CS PF04969.16 RUS86699.1 - 0.0023 18.9 51.2 2.3 9.3 2.9 6.4 1 1 9 10 10 10 8 CS domain Ribosomal_L14e PF01929.17 RUS86699.1 - 0.12 12.9 37.6 17 6.0 0.6 6.7 1 1 9 10 10 10 0 Ribosomal protein L14 DUF1320 PF07030.12 RUS86699.1 - 0.88 9.7 23.3 40 4.3 0.3 6.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1320) Lge1 PF11488.8 RUS86699.1 - 3.5 7.9 55.5 12 6.2 1.4 7.9 1 1 9 10 10 10 0 Transcriptional regulatory protein LGE1 Tic110 PF16940.5 RUS86699.1 - 4.9 5.5 30.4 6.1 5.2 2.4 4.9 1 1 7 8 8 8 0 Chloroplast envelope transporter SLT_2 PF13406.6 RUS86699.1 - 8.6 5.5 30.2 15 4.7 2.1 4.8 1 1 9 10 10 10 0 Transglycosylase SLT domain Asp_protease_2 PF13650.6 RUS86700.1 - 0.0044 17.6 0.0 0.022 15.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS86700.1 - 0.013 16.0 0.0 0.084 13.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease YebO PF13974.6 RUS86700.1 - 0.4 10.8 6.7 0.25 11.5 4.1 2.0 2 0 0 2 2 2 0 YebO-like protein TMEM154 PF15102.6 RUS86701.1 - 0.0039 17.1 1.1 0.0041 17.0 1.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family LRRC37AB_C PF14914.6 RUS86701.1 - 0.0068 16.3 1.9 0.0085 16.0 1.8 1.2 1 1 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain RIFIN PF02009.16 RUS86701.1 - 0.015 15.2 0.6 0.015 15.2 0.6 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 RUS86701.1 - 0.043 14.1 0.2 0.052 13.9 0.2 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Herpes_gE PF02480.16 RUS86701.1 - 0.053 12.3 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.6 RUS86701.1 - 0.067 13.4 0.1 0.077 13.2 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 RUS86701.1 - 0.069 12.5 5.8 0.081 12.3 5.7 1.2 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Stevor PF17410.2 RUS86701.1 - 0.07 12.7 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 RUS86701.1 - 0.071 11.9 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EMP70 PF02990.16 RUS86701.1 - 0.11 11.1 0.3 0.12 11.1 0.3 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 NCU-G1 PF15065.6 RUS86701.1 - 1 8.3 3.0 1.4 7.9 3.0 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Synaptobrevin PF00957.21 RUS86701.1 - 3.4 7.5 9.7 27 4.7 8.7 2.1 2 0 0 2 2 2 0 Synaptobrevin Lectin_C PF00059.21 RUS86702.1 - 7e-19 68.6 0.0 1.5e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain Antistasin PF02822.14 RUS86702.1 - 0.00017 22.2 10.0 0.00037 21.1 10.0 1.6 1 0 0 1 1 1 1 Antistasin family TSNAXIP1_N PF15739.5 RUS86702.1 - 0.26 11.7 0.1 0.48 10.8 0.1 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus RecA_dep_nuc PF16786.5 RUS86703.1 - 3.5e-06 27.1 4.5 8 6.7 0.0 6.0 1 1 6 7 7 7 3 Recombination enhancement, RecA-dependent nuclease P3A PF08727.11 RUS86703.1 - 0.00012 21.3 4.7 9.1 5.8 0.0 5.6 1 1 5 6 6 6 2 Poliovirus 3A protein like EpoR_lig-bind PF09067.10 RUS86703.1 - 0.0016 18.6 10.4 1.8 8.8 0.3 3.5 1 1 2 3 3 3 3 Erythropoietin receptor, ligand binding Antimicrobial19 PF08225.11 RUS86703.1 - 0.002 17.7 4.4 1.1e+02 2.5 0.0 5.9 6 0 0 6 6 6 0 Pseudin antimicrobial peptide MatP PF06303.12 RUS86703.1 - 0.0022 18.5 0.9 21 5.8 0.1 3.6 1 1 3 4 4 4 1 MatP N-terminal domain Chromadorea_ALT PF05535.12 RUS86703.1 - 0.031 14.5 0.9 22 5.3 0.0 2.9 1 1 2 3 3 3 0 Chromadorea ALT protein PheRS_DBD1 PF18552.1 RUS86703.1 - 0.3 10.9 1.9 7.8 6.3 0.0 3.0 2 2 0 2 2 2 0 PheRS DNA binding domain 1 DUF5318 PF17249.2 RUS86703.1 - 2.2 8.1 8.0 19 5.0 0.6 3.8 1 1 3 4 4 4 0 Family of unknown function (DUF5318) DUF3552 PF12072.8 RUS86704.1 - 3.2e-07 30.0 9.9 0.0032 16.9 2.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) DUF16 PF01519.16 RUS86704.1 - 0.00012 22.5 8.2 0.0095 16.4 2.6 2.1 1 1 1 2 2 2 2 Protein of unknown function DUF16 bZIP_1 PF00170.21 RUS86704.1 - 0.00053 20.0 17.2 1.3 9.1 2.1 3.9 1 1 3 4 4 4 4 bZIP transcription factor ZapB PF06005.12 RUS86704.1 - 0.0017 18.7 11.9 0.82 10.1 1.6 3.6 1 1 3 4 4 4 3 Cell division protein ZapB Involucrin2 PF06994.11 RUS86704.1 - 0.0054 16.8 0.0 4.9 7.3 0.0 3.9 1 1 0 1 1 1 1 Involucrin Phage_Gp23 PF10669.9 RUS86704.1 - 0.0073 16.6 18.5 8.2e+03 -2.9 18.5 3.7 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1735 PF08522.10 RUS86704.1 - 0.019 15.6 18.6 57 4.3 18.6 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1735) Neur_chan_LBD PF02931.23 RUS86704.1 - 0.023 14.1 11.5 1.7 8.0 11.5 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain KASH_CCD PF14662.6 RUS86704.1 - 0.083 12.7 12.1 0.25 11.1 6.0 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH V-SNARE_C PF12352.8 RUS86704.1 - 0.11 12.8 6.9 12 6.3 0.6 3.3 1 1 3 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Snf7 PF03357.21 RUS86704.1 - 2.2 7.9 16.2 20 4.7 15.4 2.3 1 1 0 1 1 1 0 Snf7 Cas9_PI2 PF18070.1 RUS86704.1 - 5.1 7.9 27.3 1.2e+02 3.5 0.2 5.0 1 1 2 3 3 2 0 CRISPR-Cas9 PI domain Anillin PF08174.11 RUS86706.1 - 7.9e-06 26.4 12.6 13 6.2 0.1 6.2 1 1 5 6 6 6 5 Cell division protein anillin NfrA_C PF13283.6 RUS86706.1 - 1.5e-05 24.6 0.3 31 4.0 0.0 5.3 1 1 5 6 6 6 2 Bacteriophage N adsorption protein A C-term SPATA6 PF14909.6 RUS86706.1 - 0.0085 16.2 0.3 7.2 6.8 0.0 3.6 1 1 5 6 6 6 1 Spermatogenesis-assoc protein 6 Tn7_TnsC_Int PF11426.8 RUS86706.1 - 0.067 13.4 14.5 93 3.3 0.1 5.9 1 1 5 6 6 6 0 Tn7 transposition regulator TnsC Innexin PF00876.18 RUS86707.1 - 3.2e-47 161.5 9.5 1.1e-46 159.8 9.5 1.7 1 1 0 1 1 1 1 Innexin DUF4773 PF15998.5 RUS86709.1 - 8.9e-30 103.6 2.6 1.5e-29 102.9 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) Fibrinogen_C PF00147.18 RUS86710.1 - 8.3e-31 107.5 0.1 1.4e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain PAN_2 PF08276.11 RUS86710.1 - 0.0069 16.5 0.7 0.025 14.7 0.7 2.1 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 RUS86710.1 - 0.011 15.6 2.3 0.011 15.6 2.3 2.4 2 0 0 2 2 2 0 PAN domain 7tm_1 PF00001.21 RUS86711.1 - 0.00033 20.1 12.4 0.0005 19.5 12.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 RUS86711.1 - 0.027 14.1 19.2 0.43 10.2 19.2 2.5 1 1 0 1 1 1 0 Srg family chemoreceptor TcpE PF12648.7 RUS86711.1 - 0.87 10.2 14.6 0.55 10.8 0.3 3.2 4 0 0 4 4 4 0 TcpE family SH2 PF00017.24 RUS86712.1 - 4.1e-10 39.6 0.1 1.9e-09 37.5 0.1 2.2 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 RUS86712.1 - 0.00024 21.4 0.0 0.00059 20.1 0.0 1.7 1 0 0 1 1 1 1 SOCS box MscS_TM PF12794.7 RUS86712.1 - 0.26 10.1 0.3 0.55 9.0 0.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Reprolysin_5 PF13688.6 RUS86713.1 - 3.5e-13 50.2 0.0 4.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS86713.1 - 2e-07 31.1 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS86713.1 - 3.8e-07 30.4 0.0 5.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 RUS86713.1 - 0.0071 16.3 0.3 0.031 14.2 0.1 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 RUS86714.1 - 5.2e-09 36.8 15.6 5.2e-09 36.8 15.6 1.8 2 0 0 2 2 2 1 Disintegrin Crp PF00325.20 RUS86714.1 - 0.16 11.6 0.3 0.42 10.3 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Ras PF00071.22 RUS86715.1 - 1.1e-40 138.9 0.0 1.4e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86715.1 - 2.2e-24 86.0 0.0 4.1e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS86715.1 - 3.8e-09 36.2 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS86715.1 - 2.2e-05 24.1 0.0 0.0039 16.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS86715.1 - 9.6e-05 22.4 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 RUS86715.1 - 0.002 18.1 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RUS86715.1 - 0.0064 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS86715.1 - 0.012 15.2 0.0 0.043 13.3 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 RUS86715.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 RUS86715.1 - 0.018 15.1 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 RUS86715.1 - 0.023 14.0 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 RUS86715.1 - 0.025 14.3 0.1 0.2 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RUS86715.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 RUS86715.1 - 0.036 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 RUS86715.1 - 0.036 14.0 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 RUS86715.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 RUS86715.1 - 0.046 13.6 0.1 0.37 10.7 0.1 2.0 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 RUS86715.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 RUS86715.1 - 0.14 11.2 0.0 16 4.5 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain G-alpha PF00503.20 RUS86715.1 - 0.19 10.9 0.0 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Reprolysin_5 PF13688.6 RUS86717.1 - 6.2e-09 36.3 0.2 1.1e-08 35.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS86717.1 - 1e-08 35.3 0.2 1.4e-08 34.9 0.2 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Trypan_PARP PF05887.11 RUS86717.1 - 1.5e-08 34.7 24.5 2.4e-08 34.0 24.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Reprolysin PF01421.19 RUS86717.1 - 1.4e-07 31.6 0.0 2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 RUS86717.1 - 7.3e-07 29.7 0.1 1.2e-06 29.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS86717.1 - 7.4e-07 29.0 0.0 9.8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like zf-C2H2 PF00096.26 RUS86718.1 - 1.3e-14 53.7 22.5 5.4e-06 26.6 3.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS86718.1 - 1.2e-12 47.7 9.2 2.2e-08 34.1 3.1 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS86718.1 - 6.5e-09 35.9 20.2 0.00049 20.7 2.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger TFIIA PF03153.13 RUS86718.1 - 0.002 18.2 16.6 0.002 18.2 16.6 3.2 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_8 PF15909.5 RUS86718.1 - 0.012 15.9 4.4 0.012 15.9 4.4 2.2 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 RUS86718.1 - 0.2 12.0 5.8 1.7 9.0 1.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS86718.1 - 0.26 11.4 22.1 0.043 13.8 1.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 RUS86718.1 - 3.1 8.3 5.3 5.7 7.5 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.12 RUS86718.1 - 4 7.0 6.8 17 5.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding PHB_acc PF05233.13 RUS86719.1 - 0.038 14.0 0.0 3e+02 1.5 0.0 5.0 5 0 0 5 5 5 0 PHB accumulation regulatory domain YABBY PF04690.13 RUS86719.1 - 6 7.4 8.2 86 3.6 0.7 4.0 1 1 4 5 5 5 0 YABBY protein PB1 PF00564.24 RUS86720.1 - 5.3e-06 26.3 0.0 9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 RUS86721.1 - 1.7e-08 34.1 5.2 3.4e-08 33.2 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 RUS86721.1 - 0.058 13.7 5.9 0.12 12.7 5.9 1.5 1 0 0 1 1 1 0 C1 domain ExbD PF02472.16 RUS86721.1 - 0.076 13.2 2.6 0.17 12.0 2.6 1.5 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR CENP-N PF05238.13 RUS86721.1 - 0.76 9.0 11.7 1.9 7.7 11.7 1.6 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PA26 PF04636.13 RUS86721.1 - 3.3 6.5 10.1 6.7 5.5 10.1 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NARP1 PF12569.8 RUS86721.1 - 3.8 6.3 22.6 6.4 5.6 22.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 RUS86721.1 - 9.8 5.8 11.0 29 4.3 11.0 1.9 1 0 0 1 1 1 0 Connexin RP-C_C PF11800.8 RUS86721.1 - 9.9 6.2 15.5 0.31 11.1 8.3 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Nucleo_P87 PF07267.11 RUS86722.1 - 0.019 13.9 3.3 0.024 13.5 3.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GCIP PF13324.6 RUS86722.1 - 0.96 9.0 5.2 1.3 8.6 5.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Moricin PF06451.11 RUS86723.1 - 0.81 9.5 2.8 11 5.9 0.5 2.4 2 0 0 2 2 2 0 Moricin DUF1387 PF07139.11 RUS86723.1 - 1.5 8.5 15.3 0.14 11.9 10.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) EIIBC-GUT_N PF03612.14 RUS86723.1 - 6.3 6.5 10.7 0.14 11.8 2.3 2.5 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus KH_4 PF13083.6 RUS86724.1 - 0.00048 19.9 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 2 KH domain CLZ PF16526.5 RUS86724.1 - 0.001 19.4 2.4 0.001 19.4 2.4 2.1 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 RUS86724.1 - 0.016 15.3 17.2 0.3 11.2 5.7 3.3 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.18 RUS86724.1 - 0.016 15.4 3.2 0.016 15.4 3.2 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper ZapB PF06005.12 RUS86724.1 - 0.035 14.6 3.0 0.035 14.6 3.0 2.7 2 1 0 2 2 2 0 Cell division protein ZapB NUDE_C PF04880.13 RUS86724.1 - 0.037 14.5 1.9 0.31 11.5 0.1 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region GPS2_interact PF15784.5 RUS86724.1 - 0.038 14.4 2.1 0.11 13.0 2.1 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Cnn_1N PF07989.11 RUS86724.1 - 0.59 10.3 8.6 0.27 11.4 2.5 3.1 3 1 1 4 4 3 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 RUS86724.1 - 0.88 9.5 4.3 1.3 8.9 1.4 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 RUS86724.1 - 1.1 9.9 10.2 28 5.4 6.7 3.0 1 1 1 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 RUS86724.1 - 1.7 8.8 11.2 0.68 10.1 7.3 2.3 1 1 1 2 2 2 0 Tropomyosin like TSC22 PF01166.18 RUS86724.1 - 1.8 8.9 12.6 0.66 10.3 0.9 4.2 4 1 1 5 5 4 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 RUS86724.1 - 2.7 8.3 9.6 5.4 7.3 8.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 RUS86724.1 - 3.2 7.1 15.6 3.7 6.8 13.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 RUS86724.1 - 4.6 7.4 16.2 5.2 7.3 10.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 RUS86724.1 - 5.2 7.3 12.9 0.68 10.1 6.9 2.6 3 1 0 3 3 2 0 JNK-interacting protein leucine zipper II Csm1_N PF18504.1 RUS86724.1 - 6.8 7.1 12.9 0.19 12.1 3.6 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain KASH_CCD PF14662.6 RUS86724.1 - 8.6 6.1 16.2 0.33 10.8 5.2 2.9 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH CTD PF12815.7 RUS86727.1 - 1.4 9.6 4.7 9.1 6.9 4.7 2.2 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Ank_4 PF13637.6 RUS86728.1 - 5.1e-18 65.2 0.5 1.8e-07 31.5 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS86728.1 - 1.4e-17 63.5 0.3 2.9e-07 30.6 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS86728.1 - 1.3e-16 60.9 0.1 3.3e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS86728.1 - 2.2e-09 36.8 1.0 0.002 18.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS86728.1 - 1.6e-08 34.6 0.1 0.01 16.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat HTH_16 PF12645.7 RUS86728.1 - 0.071 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Trypsin_2 PF13365.6 RUS86729.1 - 3.7e-07 31.2 1.1 2.3e-05 25.3 0.1 2.4 1 1 1 2 2 2 2 Trypsin-like peptidase domain Potex_coat PF06184.11 RUS86729.1 - 0.099 12.2 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Potexvirus coat protein Innexin PF00876.18 RUS86730.1 - 1.1e-88 297.9 14.0 1.3e-88 297.6 14.0 1.0 1 0 0 1 1 1 1 Innexin Anticodon_1 PF08264.13 RUS86731.1 - 1.7e-13 50.8 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RUS86731.1 - 3.3e-11 42.6 0.0 6.1e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RUS86731.1 - 1.1e-08 33.9 0.0 0.00045 18.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 RUS86731.1 - 3.9e-06 26.4 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 RUS86732.1 - 1.8e-43 148.7 0.0 9.4e-31 106.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RUS86732.1 - 1.3e-19 70.2 0.0 2.1e-10 39.9 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RUS86732.1 - 2.1e-17 63.5 0.1 6.2e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RUS86732.1 - 6.9e-07 28.9 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2870 PF11069.8 RUS86733.1 - 4.1e-45 152.1 2.7 8.7e-45 151.1 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DUF3585 PF12130.8 RUS86734.1 - 3.7e-40 137.2 17.5 3.7e-40 137.2 17.5 2.3 2 0 0 2 2 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 RUS86734.1 - 7.3e-20 71.2 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS86734.1 - 9e-09 35.1 0.0 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain FAD_binding_3 PF01494.19 RUS86734.1 - 2.7e-05 23.6 0.0 7.4e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 RUS86734.1 - 8.2e-05 21.9 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 RUS86734.1 - 0.00017 20.9 0.0 0.00043 19.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS86734.1 - 0.0013 18.1 0.0 0.0028 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase LIM PF00412.22 RUS86734.1 - 0.0013 18.9 7.6 0.0027 17.9 7.6 1.5 1 0 0 1 1 1 1 LIM domain FAD_oxidored PF12831.7 RUS86734.1 - 0.0017 17.8 0.0 0.0043 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS86734.1 - 0.0034 16.1 0.0 0.0034 16.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 RUS86734.1 - 0.004 16.8 0.0 0.041 13.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 RUS86734.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 RUS86734.1 - 0.042 14.4 1.1 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS86734.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 RUS86734.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oscp1 PF10188.9 RUS86737.1 - 1.5e-77 259.7 10.5 2e-77 259.3 10.5 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 DUF758 PF05527.11 RUS86737.1 - 0.028 14.4 0.1 0.078 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF758) DUF2304 PF10066.9 RUS86738.1 - 2.7 8.3 11.0 2.8 8.2 3.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) BPL_LplA_LipB PF03099.19 RUS86739.1 - 7.1e-19 68.0 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 RUS86739.1 - 1.5e-09 37.5 0.1 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_C PF02237.17 RUS86739.1 - 5.4e-09 35.8 2.1 4.4e-08 32.9 0.3 2.7 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain IL34 PF15036.6 RUS86740.1 - 0.027 14.5 0.5 0.035 14.1 0.5 1.2 1 0 0 1 1 1 0 Interleukin 34 MPC PF03650.13 RUS86741.1 - 3.6e-26 91.5 0.1 5.3e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Erythrovirus_X PF06795.11 RUS86741.1 - 0.14 12.5 0.4 7.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Erythrovirus X protein Integrase_H2C2 PF17921.1 RUS86742.1 - 3.4e-13 49.5 0.1 5.8e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS86742.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain EF-hand_6 PF13405.6 RUS86743.1 - 2.7e-11 42.4 0.4 0.0021 17.8 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 RUS86743.1 - 1.8e-08 33.3 0.1 0.0023 17.4 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 RUS86743.1 - 7.1e-07 29.6 6.2 0.026 15.0 0.0 4.5 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_11 PF08976.11 RUS86743.1 - 0.00023 22.0 1.1 9.5 7.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RUS86743.1 - 0.094 12.6 0.2 12 5.9 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair RST PF12174.8 RUS86743.1 - 0.19 11.6 7.3 7.5 6.5 0.1 4.4 4 0 0 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain IF4E PF01652.18 RUS86744.1 - 6.7e-55 185.2 0.1 8e-55 185.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Gal_Lectin PF02140.18 RUS86745.1 - 8.9 6.8 7.0 0.56 10.7 1.0 2.2 2 0 0 2 2 2 0 Galactose binding lectin domain GAF PF01590.26 RUS86748.1 - 1.8e-07 31.9 0.0 3.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RUS86749.1 - 0.022 15.1 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 GAF domain DUF1660 PF07874.11 RUS86749.1 - 0.05 14.1 0.4 0.098 13.2 0.2 1.6 1 1 0 1 1 1 0 Prophage protein (DUF1660) Chordopox_A15 PF05846.12 RUS86749.1 - 0.1 12.8 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A15 protein PDEase_I PF00233.19 RUS86750.1 - 5.4e-80 268.5 3.0 8.6e-80 267.9 3.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RUS86750.1 - 0.063 13.5 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 HD domain CDC45 PF02724.14 RUS86750.1 - 4.3 5.5 11.8 14 3.8 12.4 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF1682 PF07946.14 RUS86750.1 - 6.1 6.0 11.4 11 5.1 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Lon_C PF05362.13 RUS86752.1 - 5.1e-71 238.5 0.0 2.4e-70 236.3 0.0 2.1 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 RUS86752.1 - 6.8e-36 124.1 0.6 6.8e-36 124.1 0.6 1.9 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RUS86752.1 - 2.8e-24 86.0 0.0 1.1e-23 84.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS86752.1 - 6.5e-09 35.9 0.0 3.1e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RUS86752.1 - 5.6e-08 33.1 0.0 1.7e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 RUS86752.1 - 3e-06 27.1 0.0 9.7e-06 25.4 0.0 1.8 1 1 1 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 RUS86752.1 - 4.9e-06 25.7 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 RUS86752.1 - 1.1e-05 25.9 1.0 6.2e-05 23.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 RUS86752.1 - 1.4e-05 24.9 0.0 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS86752.1 - 9.7e-05 22.7 0.2 0.0046 17.2 0.0 3.4 3 1 0 3 3 1 1 AAA domain RNA_helicase PF00910.22 RUS86752.1 - 0.00051 20.4 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 RUS86752.1 - 0.002 18.1 0.3 0.0073 16.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 RUS86752.1 - 0.0058 16.6 3.6 0.45 10.4 0.0 3.6 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 RUS86752.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RUS86752.1 - 0.014 15.3 0.0 0.054 13.4 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 RUS86752.1 - 0.016 14.9 0.1 0.063 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RUS86752.1 - 0.028 13.6 1.1 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 RUS86752.1 - 0.032 14.8 0.0 0.032 14.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RUS86752.1 - 0.033 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 RUS86752.1 - 0.057 13.3 0.1 0.32 10.9 0.0 2.2 1 1 1 2 2 2 0 NTPase Parvo_NS1 PF01057.17 RUS86752.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 RUS86752.1 - 0.07 13.0 0.0 0.23 11.3 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RUS86752.1 - 0.089 13.3 0.0 0.089 13.3 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_3 PF07726.11 RUS86752.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RUS86752.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RUS86752.1 - 0.14 12.7 0.9 0.59 10.6 0.0 2.5 3 0 0 3 3 2 0 ABC transporter AAA_30 PF13604.6 RUS86752.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 RUS86752.1 - 0.22 11.9 2.9 0.48 10.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP-cone PF03477.16 RUS86752.1 - 0.28 11.8 3.9 0.87 10.2 0.1 3.3 3 0 0 3 3 3 0 ATP cone domain Ig_3 PF13927.6 RUS86753.1 - 2.1e-27 95.5 2.1 1e-08 35.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS86753.1 - 3e-27 94.5 0.0 3.4e-10 39.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RUS86753.1 - 9.6e-19 67.4 0.2 1.2e-05 25.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS86753.1 - 1.4e-18 67.0 0.9 7.5e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS86753.1 - 9.2e-17 61.2 2.8 3.9e-09 36.7 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS86753.1 - 0.00012 22.3 0.0 1.8 8.9 0.2 3.9 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 RUS86753.1 - 0.00015 21.7 0.0 0.018 15.1 0.0 3.1 3 0 0 3 3 3 1 C17orf99 Ig domain C2-set_2 PF08205.12 RUS86753.1 - 0.003 17.6 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS86753.1 - 0.022 14.8 0.1 6.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS86753.1 - 0.044 13.3 0.0 1.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin domain zf-C4 PF00105.18 RUS86754.1 - 3.6e-23 81.8 12.6 8.1e-23 80.7 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS86754.1 - 1.7e-07 31.0 4.4 1.9e-07 30.9 1.5 2.5 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 RUS86754.1 - 0.05 13.7 6.6 0.061 13.4 5.2 1.9 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING_2 PF13639.6 RUS86754.1 - 2.8 8.4 8.2 54 4.2 8.2 2.4 1 1 0 1 1 1 0 Ring finger domain AMP-binding PF00501.28 RUS86755.1 - 1.3e-56 192.1 0.0 1.6e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS86755.1 - 3.6e-05 24.6 0.0 7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YmzC PF14157.6 RUS86755.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 YmzC-like protein BUD22 PF09073.10 RUS86756.1 - 1.1e-09 38.2 9.4 1.1e-09 38.2 9.4 3.8 1 1 2 3 3 3 2 BUD22 ADAM_spacer1 PF05986.14 RUS86757.1 - 2e-20 73.0 0.0 2.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 RUS86757.1 - 7.4e-15 54.9 57.6 7.5e-07 29.3 6.6 6.4 5 2 0 5 5 5 4 Thrombospondin type 1 domain PLAC PF08686.11 RUS86757.1 - 3.5e-09 37.2 11.7 1.6e-08 35.2 11.7 2.3 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Glyco_trans_1_2 PF13524.6 RUS86757.1 - 0.11 12.9 0.6 0.32 11.4 0.6 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Kelch_6 PF13964.6 RUS86758.1 - 2.4e-35 119.6 2.3 4e-07 30.1 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RUS86758.1 - 4.7e-30 103.3 12.7 1.9e-07 30.9 0.0 6.5 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS86758.1 - 1.3e-29 101.5 0.9 0.00021 20.8 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS86758.1 - 1.4e-27 95.4 0.3 1e-06 28.9 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS86758.1 - 3.4e-25 87.6 1.5 2.8e-06 27.2 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 RUS86758.1 - 1.1e-21 75.9 9.6 0.00037 20.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif WYL_2 PF10902.8 RUS86758.1 - 0.13 12.7 0.0 7.8 7.0 0.0 2.5 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold RT_RNaseH PF17917.1 RUS86760.1 - 2.9e-06 27.5 0.0 7.8e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS86760.1 - 0.0002 21.5 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 RUS86760.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain P16-Arc PF04699.14 RUS86760.1 - 0.093 13.2 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) AP-5_subunit_s1 PF15001.6 RUS86761.1 - 6.1e-36 124.2 0.5 6.5e-36 124.1 0.5 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 Clat_adaptor_s PF01217.20 RUS86761.1 - 5e-06 26.5 0.4 3.7e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Thg1 PF04446.12 RUS86761.1 - 0.045 13.8 0.1 0.1 12.7 0.1 1.6 1 1 1 2 2 2 0 tRNAHis guanylyltransferase PilZ PF07238.14 RUS86761.1 - 0.057 13.7 0.1 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 PilZ domain TRAP_beta PF05753.14 RUS86762.1 - 2.5e-31 108.5 0.7 2.2e-11 43.5 0.0 3.0 1 1 2 3 3 3 3 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 RUS86762.1 - 0.00072 19.8 0.1 0.00098 19.3 0.1 1.2 1 0 0 1 1 1 1 CARDB ATP-synt_ab PF00006.25 RUS86763.1 - 2.2e-60 204.0 0.0 3.2e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RUS86763.1 - 7.3e-21 74.5 1.0 1.5e-20 73.5 1.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 RUS86763.1 - 0.0043 16.3 0.1 0.0085 15.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 RUS86763.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 RUS86763.1 - 0.028 14.8 0.0 0.68 10.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RUS86763.1 - 0.037 13.9 0.1 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 RUS86763.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 RUS86763.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 RUS86763.1 - 0.11 11.8 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 RUS86763.1 - 0.11 12.8 0.8 0.38 11.1 0.2 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RUS86763.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 RUS86763.1 - 0.19 10.9 0.1 0.47 9.6 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) T3SS_ATPase_C PF18269.1 RUS86763.1 - 0.25 11.2 0.7 1.5 8.7 0.7 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain CwsA PF10814.8 RUS86764.1 - 2.4 8.4 3.9 1.3 9.2 1.3 1.8 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA PikAIV_N PF18605.1 RUS86764.1 - 3.8 7.2 11.6 0.11 12.1 0.6 3.8 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Phage_lysis PF03245.13 RUS86764.1 - 5.4 7.2 29.1 0.61 10.2 18.2 3.8 2 2 3 5 5 5 0 Bacteriophage Rz lysis protein MutS_IV PF05190.18 RUS86764.1 - 6.7 7.1 21.8 0.81 10.1 3.3 4.0 3 1 0 3 3 3 0 MutS family domain IV YabA PF06156.13 RUS86764.1 - 8.4 7.1 47.8 1.5 9.5 4.9 5.5 1 1 2 5 5 5 0 Initiation control protein YabA DUF3037 PF11236.8 RUS86764.1 - 10 6.6 13.4 0.81 10.1 0.5 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF3037) ODV-E18 PF10717.9 RUS86765.1 - 0.16 11.8 0.4 0.31 10.9 0.4 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4500 PF14937.6 RUS86766.1 - 6.4e-28 96.6 0.0 7.4e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) MadM PF03818.13 RUS86766.1 - 0.026 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit DNA_pol_A_exo1 PF01612.20 RUS86768.1 - 1.4e-06 28.2 0.0 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease EcoEI_R_C PF08463.10 RUS86768.1 - 0.054 13.6 0.3 0.08 13.1 0.3 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal Anillin PF08174.11 RUS86769.1 - 6.4e-46 156.3 1.2 1.7e-45 154.9 0.0 2.2 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 RUS86769.1 - 1.5e-12 48.0 0.0 4.8e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 PH domain HR1 PF02185.16 RUS86769.1 - 1e-06 28.7 1.6 3e-06 27.2 1.6 1.8 1 0 0 1 1 1 1 Hr1 repeat DUF4909 PF16253.5 RUS86769.1 - 0.079 12.8 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Spp-24 PF07448.11 RUS86769.1 - 0.28 11.4 3.5 17 5.7 0.1 3.5 3 0 0 3 3 3 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain ESF1 PF18209.1 RUS86769.1 - 1.4 8.9 9.1 0.054 13.4 3.0 1.8 2 0 0 2 2 2 0 Embryo surrounding factor 1 Sec7 PF01369.20 RUS86770.1 - 2.4e-49 167.5 0.5 2.6e-49 167.4 0.5 1.0 1 0 0 1 1 1 1 Sec7 domain Gp37 PF09646.10 RUS86770.1 - 0.069 13.0 0.0 0.098 12.5 0.0 1.3 1 1 0 1 1 1 0 Gp37 protein NDUFB10 PF10249.9 RUS86770.1 - 0.092 13.3 0.1 0.15 12.6 0.1 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Ephrin_rec_like PF07699.13 RUS86771.1 - 7.8e-13 48.0 46.0 0.00011 21.9 8.8 4.6 1 1 4 5 5 5 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 RUS86771.1 - 0.016 15.6 39.5 0.17 12.3 1.1 5.5 1 1 6 7 7 7 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 RUS86771.1 - 0.018 13.9 30.8 0.86 8.4 16.1 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein Ephrin_rec_like PF07699.13 RUS86772.1 - 6.2e-25 86.7 65.0 5.6e-08 32.4 4.9 6.4 1 1 5 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 RUS86772.1 - 5.8e-05 23.0 50.9 0.0019 18.1 6.3 6.3 2 1 4 6 6 6 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS86772.1 - 0.089 13.2 51.0 0.35 11.3 8.2 7.5 2 2 4 7 7 6 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 RUS86772.1 - 0.11 11.4 50.5 0.17 10.7 25.5 2.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein 2-Hacid_dh PF00389.30 RUS86773.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Exo_endo_phos_2 PF14529.6 RUS86773.1 - 0.0034 17.2 0.0 0.0083 16.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase adh_short PF00106.25 RUS86774.1 - 1.4e-36 125.8 0.0 1.7e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS86774.1 - 5.6e-20 71.9 0.0 7.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS86774.1 - 0.00018 21.4 1.5 0.001 19.0 1.5 1.9 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS86774.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 RUS86774.1 - 0.015 14.4 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 RUS86774.1 - 0.03 14.2 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 RUS86774.1 - 0.033 13.7 0.3 0.052 13.0 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 RUS86774.1 - 0.051 12.9 0.1 0.059 12.7 0.1 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4431 PF14485.6 RUS86774.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) ApbA PF02558.16 RUS86774.1 - 0.064 12.9 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 RUS86774.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4796 PF16044.5 RUS86775.1 - 1e-41 142.6 0.0 1.4e-27 96.5 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4796) FlaC_arch PF05377.11 RUS86777.1 - 2.8e-14 53.2 26.6 0.0012 19.2 2.3 4.1 1 1 3 4 4 4 4 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 RUS86777.1 - 2.9e-14 53.3 37.4 2.1e+02 2.4 37.4 3.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.13 RUS86777.1 - 4.3e-14 52.7 11.2 0.025 14.9 1.1 5.0 1 1 4 5 5 5 5 Uncharacterised protein family (UPF0184) XhlA PF10779.9 RUS86777.1 - 7.1e-14 51.8 92.8 0.00021 21.4 11.2 4.0 1 1 4 5 5 5 5 Haemolysin XhlA MscS_porin PF12795.7 RUS86777.1 - 2e-12 47.2 10.8 4.2e-07 29.7 5.2 2.3 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain CLZ PF16526.5 RUS86777.1 - 3.7e-11 43.2 25.3 0.0095 16.3 5.7 4.4 1 1 3 4 4 4 4 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 RUS86777.1 - 7.7e-11 42.1 6.9 0.29 11.4 0.2 4.7 1 1 2 4 4 4 3 Proteins of 100 residues with WXG RmuC PF02646.16 RUS86777.1 - 3.5e-10 39.5 23.1 0.00015 21.0 7.4 2.9 1 1 1 2 2 2 2 RmuC family Snapin_Pallidin PF14712.6 RUS86777.1 - 6.6e-10 39.3 37.1 0.0054 17.1 10.9 3.9 1 1 1 3 3 3 3 Snapin/Pallidin Baculo_PEP_C PF04513.12 RUS86777.1 - 2.4e-09 37.4 20.8 4.1e-05 23.7 20.8 2.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 RUS86777.1 - 3e-09 36.3 24.4 3.7e-05 22.9 9.4 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 EzrA PF06160.12 RUS86777.1 - 4.1e-09 35.2 32.7 5.2e-08 31.5 32.5 2.0 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_II PF06009.12 RUS86777.1 - 6.4e-09 35.9 28.1 6e-05 23.1 13.6 2.1 1 1 1 2 2 2 2 Laminin Domain II DUF1664 PF07889.12 RUS86777.1 - 1.8e-08 34.5 28.8 9.6e-05 22.4 14.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF2730 PF10805.8 RUS86777.1 - 7.1e-08 32.5 25.1 0.0048 17.0 7.6 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF2730) Spc7 PF08317.11 RUS86777.1 - 2.4e-07 30.0 29.6 5.3e-06 25.5 29.6 2.1 1 1 0 1 1 1 1 Spc7 kinetochore protein Sec34 PF04136.15 RUS86777.1 - 2.8e-07 30.5 23.0 0.00039 20.3 10.8 2.1 1 1 1 2 2 2 2 Sec34-like family DASH_Duo1 PF08651.10 RUS86777.1 - 6e-07 29.2 23.1 0.11 12.3 2.7 4.0 1 1 3 4 4 4 4 DASH complex subunit Duo1 TPR_MLP1_2 PF07926.12 RUS86777.1 - 9.5e-07 28.9 17.3 0.047 13.7 2.5 3.3 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Nup54 PF13874.6 RUS86777.1 - 1e-06 28.9 15.5 0.00044 20.4 15.5 2.1 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 YojJ PF10372.9 RUS86777.1 - 1.1e-06 28.7 30.9 1.8e+04 -8.1 30.9 4.4 1 1 0 1 1 0 0 Bacterial membrane-spanning protein N-terminus COG2 PF06148.11 RUS86777.1 - 2.2e-06 27.8 11.4 0.15 12.2 7.5 3.4 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Allexi_40kDa PF05549.11 RUS86777.1 - 2.3e-06 27.4 25.4 0.0033 17.0 10.1 2.1 1 1 1 2 2 2 2 Allexivirus 40kDa protein FliJ PF02050.16 RUS86777.1 - 2.4e-06 27.8 7.1 0.00047 20.4 7.1 3.0 1 1 0 1 1 1 1 Flagellar FliJ protein TelA PF05816.11 RUS86777.1 - 2.6e-06 26.7 30.8 0.018 14.1 21.6 2.9 1 1 1 2 2 2 2 Toxic anion resistance protein (TelA) TolA_bind_tri PF16331.5 RUS86777.1 - 3.6e-06 27.0 5.7 0.044 13.9 1.0 3.0 1 1 2 3 3 3 3 TolA binding protein trimerisation Tropomyosin PF00261.20 RUS86777.1 - 3.7e-06 26.5 24.3 0.0029 17.0 9.8 2.1 1 1 1 2 2 2 2 Tropomyosin COG6 PF06419.11 RUS86777.1 - 4e-06 25.3 27.3 0.0077 14.5 10.8 2.4 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 DUF16 PF01519.16 RUS86777.1 - 4.1e-06 27.2 35.7 0.0027 18.2 15.5 2.0 1 1 1 2 2 2 2 Protein of unknown function DUF16 HrpB7 PF09486.10 RUS86777.1 - 6.1e-06 26.7 6.7 0.054 13.9 1.4 2.9 1 1 2 3 3 3 3 Bacterial type III secretion protein (HrpB7) MtrG PF04210.13 RUS86777.1 - 6.1e-06 26.0 33.4 5.9 6.8 0.7 7.9 1 1 6 7 7 7 0 Tetrahydromethanopterin S-methyltransferase, subunit G ABC_tran_CTD PF16326.5 RUS86777.1 - 1.2e-05 25.5 22.0 7.9e+02 0.4 22.0 3.4 1 1 0 1 1 0 0 ABC transporter C-terminal domain EMP24_GP25L PF01105.24 RUS86777.1 - 1.2e-05 25.3 25.5 1.6e+04 -4.4 25.5 4.2 1 1 0 1 1 0 0 emp24/gp25L/p24 family/GOLD DUF4201 PF13870.6 RUS86777.1 - 1.2e-05 25.1 39.4 0.0072 16.1 21.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) DUF4763 PF15960.5 RUS86777.1 - 1.3e-05 24.7 35.8 0.42 9.9 1.9 5.2 1 1 6 7 7 7 3 Domain of unknown function (DUF4763) Exonuc_VII_L PF02601.15 RUS86777.1 - 1.5e-05 24.7 16.3 3.3e-05 23.6 16.3 1.5 1 1 0 1 1 1 1 Exonuclease VII, large subunit WEMBL PF05701.11 RUS86777.1 - 2.2e-05 23.4 20.1 3.2e-05 22.8 20.1 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light FPP PF05911.11 RUS86777.1 - 4.2e-05 22.0 22.5 5e-05 21.7 22.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Remorin_C PF03763.13 RUS86777.1 - 4.4e-05 23.3 28.3 0.74 9.7 7.2 3.9 1 1 1 2 2 2 1 Remorin, C-terminal region DUF2408 PF10303.9 RUS86777.1 - 4.9e-05 23.9 28.5 0.031 14.9 28.5 3.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) MCPsignal PF00015.21 RUS86777.1 - 4.9e-05 23.2 9.8 0.013 15.4 2.1 2.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Prefoldin_2 PF01920.20 RUS86777.1 - 5.4e-05 23.1 42.8 0.93 9.5 8.3 4.1 1 1 4 5 5 5 0 Prefoldin subunit APG6_N PF17675.1 RUS86777.1 - 5.9e-05 23.6 19.7 0.00018 22.0 19.7 1.7 1 1 0 1 1 1 1 Apg6 coiled-coil region TMPIT PF07851.13 RUS86777.1 - 6.4e-05 22.3 27.3 0.0033 16.7 15.1 2.0 1 1 1 2 2 2 2 TMPIT-like protein SKA2 PF16740.5 RUS86777.1 - 6.5e-05 22.7 21.2 0.62 9.9 21.2 3.7 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 OmpH PF03938.14 RUS86777.1 - 7.9e-05 23.0 29.8 0.66 10.3 29.8 2.2 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) FH2 PF02181.23 RUS86777.1 - 8.8e-05 21.8 21.3 0.014 14.5 8.9 2.0 1 1 1 2 2 2 2 Formin Homology 2 Domain DASH_Spc19 PF08287.11 RUS86777.1 - 9.1e-05 22.4 28.2 1.8 8.4 9.5 3.8 1 1 1 2 2 2 0 Spc19 KxDL PF10241.9 RUS86777.1 - 0.00013 22.1 43.5 0.36 11.1 8.4 4.4 1 1 4 5 5 5 2 Uncharacterized conserved protein Fusion_gly PF00523.18 RUS86777.1 - 0.00018 19.9 19.2 0.061 11.6 7.0 2.6 1 1 1 2 2 2 2 Fusion glycoprotein F0 APG17 PF04108.12 RUS86777.1 - 0.0002 20.6 24.6 0.019 14.1 24.5 2.4 1 1 0 1 1 1 1 Autophagy protein Apg17 Vps52 PF04129.12 RUS86777.1 - 0.00023 20.1 19.1 0.05 12.4 9.0 2.2 1 1 1 2 2 2 2 Vps52 / Sac2 family Alanine_zipper PF11839.8 RUS86777.1 - 0.00026 21.3 9.2 13 6.2 0.2 4.8 1 1 7 8 8 8 0 Alanine-zipper, major outer membrane lipoprotein DHR10 PF18595.1 RUS86777.1 - 0.0003 20.8 23.8 2.1 8.4 23.8 2.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 RUS86777.1 - 0.00032 21.2 18.7 0.0013 19.3 18.7 1.8 1 1 0 1 1 1 1 Fez1 CENP-F_leu_zip PF10473.9 RUS86777.1 - 0.00036 20.6 27.0 0.0069 16.4 17.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 RUS86777.1 - 0.00042 21.2 25.2 9.7e+03 -2.5 25.2 4.2 1 1 0 1 1 0 0 cGMP-dependent protein kinase interacting domain Plasmid_RAQPRD PF09686.10 RUS86777.1 - 0.00047 20.3 11.9 7.6e+02 0.4 11.9 5.1 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Bcr-Abl_Oligo PF09036.10 RUS86777.1 - 0.00048 20.1 19.1 0.46 10.5 2.3 3.3 1 1 2 3 3 3 2 Bcr-Abl oncoprotein oligomerisation domain DUF3450 PF11932.8 RUS86777.1 - 0.0005 19.4 23.2 0.022 14.1 10.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) YkyA PF10368.9 RUS86777.1 - 0.00054 19.7 32.6 0.081 12.6 16.8 2.1 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein DUF745 PF05335.13 RUS86777.1 - 0.00058 19.6 14.9 0.0022 17.8 10.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF745) THOC7 PF05615.13 RUS86777.1 - 0.00058 20.1 19.4 0.027 14.7 12.3 2.2 1 1 1 2 2 2 2 Tho complex subunit 7 HSBP1 PF06825.12 RUS86777.1 - 0.00066 19.5 27.4 1.8e+04 -10.3 27.4 4.8 1 1 0 1 1 0 0 Heat shock factor binding protein 1 CREPT PF16566.5 RUS86777.1 - 0.00067 19.8 26.5 2 8.6 4.2 4.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Vps51 PF08700.11 RUS86777.1 - 0.00069 19.7 24.9 2.3 8.3 1.7 4.7 1 1 4 5 5 5 0 Vps51/Vps67 BLOC1_2 PF10046.9 RUS86777.1 - 0.0007 19.9 28.8 2e+03 -0.9 28.8 3.1 1 1 0 1 1 0 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 RUS86777.1 - 0.00071 19.8 27.7 0.0035 17.5 27.7 2.0 1 1 0 1 1 1 1 Tropomyosin like Uds1 PF15456.6 RUS86777.1 - 0.00071 19.7 21.5 0.4 10.8 21.5 2.5 1 1 0 1 1 1 1 Up-regulated During Septation YabA PF06156.13 RUS86777.1 - 0.00075 20.1 19.4 0.4 11.4 10.6 2.6 1 1 1 2 2 2 1 Initiation control protein YabA T3SSipB PF16535.5 RUS86777.1 - 0.00078 19.9 28.5 65 4.0 28.5 3.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB Fmp27_WPPW PF10359.9 RUS86777.1 - 0.00079 18.4 27.5 0.073 11.9 12.3 2.0 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain PspA_IM30 PF04012.12 RUS86777.1 - 0.00082 19.0 28.8 0.47 10.0 8.1 3.0 1 1 1 2 2 2 1 PspA/IM30 family DUF3584 PF12128.8 RUS86777.1 - 0.00082 17.0 21.4 0.00095 16.8 21.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Syntaxin PF00804.25 RUS86777.1 - 0.00089 19.0 31.3 0.059 13.0 13.6 2.1 1 1 1 2 2 2 2 Syntaxin Filament PF00038.21 RUS86777.1 - 0.0009 18.9 22.0 0.25 10.9 6.8 2.4 1 1 0 2 2 2 2 Intermediate filament protein DUF4407 PF14362.6 RUS86777.1 - 0.00095 18.6 21.1 0.0034 16.8 21.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Dor1 PF04124.12 RUS86777.1 - 0.0013 17.5 17.4 0.16 10.7 3.9 2.7 1 1 1 2 2 2 1 Dor1-like family Spc24 PF08286.11 RUS86777.1 - 0.0013 18.9 22.4 1.3e+04 -3.6 22.4 3.7 1 1 0 1 1 0 0 Spc24 subunit of Ndc80 Muted PF14942.6 RUS86777.1 - 0.0013 19.1 23.4 1 9.7 23.4 2.3 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Vps5 PF09325.10 RUS86777.1 - 0.0014 18.3 28.1 0.19 11.3 8.7 2.8 1 1 3 4 4 4 4 Vps5 C terminal like ERM PF00769.19 RUS86777.1 - 0.0015 18.4 13.5 0.0019 18.1 13.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Rx_N PF18052.1 RUS86777.1 - 0.0015 18.8 21.5 4.8 7.5 5.5 4.1 1 1 1 2 2 2 0 Rx N-terminal domain Fzo_mitofusin PF04799.13 RUS86777.1 - 0.0018 17.8 23.9 0.64 9.6 10.2 2.9 1 1 1 2 2 2 1 fzo-like conserved region DUF5082 PF16888.5 RUS86777.1 - 0.0019 18.5 28.1 4.5 7.6 28.1 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FadA PF09403.10 RUS86777.1 - 0.0025 18.3 25.0 1e+02 3.4 25.0 3.5 1 1 0 1 1 1 0 Adhesion protein FadA HIP1_clath_bdg PF16515.5 RUS86777.1 - 0.0026 18.3 19.3 72 4.1 19.3 2.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COG5 PF10392.9 RUS86777.1 - 0.0027 17.9 18.0 2.2 8.4 18.0 2.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-SNARE_C PF12352.8 RUS86777.1 - 0.0027 18.0 26.0 3.2 8.1 2.2 4.5 1 1 5 6 6 6 0 Snare region anchored in the vesicle membrane C-terminus DegS PF05384.11 RUS86777.1 - 0.0027 17.2 22.0 0.0067 15.9 22.0 1.9 1 1 0 1 1 1 1 Sensor protein DegS Sec2p PF06428.11 RUS86777.1 - 0.0028 17.6 33.0 0.56 10.2 5.8 3.3 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p DUF724 PF05266.14 RUS86777.1 - 0.0031 17.4 28.1 0.014 15.2 17.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF724) Lipoprotein_2 PF00921.17 RUS86777.1 - 0.0033 17.0 29.7 0.26 10.8 12.5 2.7 1 1 1 2 2 2 1 Borrelia lipoprotein ALIX_LYPXL_bnd PF13949.6 RUS86777.1 - 0.0033 16.8 20.3 1.3 8.3 4.1 3.2 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV FemAB PF02388.16 RUS86777.1 - 0.0037 16.2 27.9 0.29 10.0 12.8 2.2 1 1 1 2 2 2 2 FemAB family Golgin_A5 PF09787.9 RUS86777.1 - 0.0038 16.7 17.7 0.0077 15.7 17.7 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 5 ADIP PF11559.8 RUS86777.1 - 0.0041 17.2 31.1 0.28 11.3 13.2 2.0 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.18 RUS86777.1 - 0.0044 17.2 13.5 6.7 6.8 13.5 2.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Flagellin_C PF00700.21 RUS86777.1 - 0.0047 17.2 10.1 51 4.3 10.1 3.1 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region SKA1 PF07160.12 RUS86777.1 - 0.0051 16.7 27.9 3.5e+02 0.9 27.9 2.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FliD_N PF02465.18 RUS86777.1 - 0.0059 17.3 34.2 1.8e+04 -11.6 34.2 4.0 1 1 0 1 1 0 0 Flagellar hook-associated protein 2 N-terminus ISG65-75 PF11727.8 RUS86777.1 - 0.0062 15.8 26.7 0.28 10.4 12.8 2.1 1 1 1 2 2 2 2 Invariant surface glycoprotein MCC-bdg_PDZ PF10506.9 RUS86777.1 - 0.0063 16.5 13.6 11 6.1 0.7 4.6 1 1 5 6 6 6 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Uso1_p115_C PF04871.13 RUS86777.1 - 0.0067 16.8 22.2 0.17 12.2 8.8 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC-167 PF15188.6 RUS86777.1 - 0.0067 16.7 20.3 1.8e+03 -0.7 20.3 3.9 1 1 0 1 1 0 0 Coiled-coil domain-containing protein 167 AmpE PF17113.5 RUS86777.1 - 0.0081 15.5 0.0 7 5.9 0.0 2.9 1 1 3 4 4 4 0 Regulatory signalling modulator protein AmpE Cluap1 PF10234.9 RUS86777.1 - 0.0086 15.5 35.5 0.3 10.5 10.8 2.9 1 1 2 3 3 3 2 Clusterin-associated protein-1 AAA_13 PF13166.6 RUS86777.1 - 0.0086 14.8 27.2 0.01 14.5 27.2 1.1 1 0 0 1 1 1 1 AAA domain HAUS-augmin3 PF14932.6 RUS86777.1 - 0.0094 15.6 18.7 0.38 10.3 7.2 2.0 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 YscO PF07321.12 RUS86777.1 - 0.0099 15.8 12.6 0.46 10.4 4.2 2.2 1 1 1 2 2 2 2 Type III secretion protein YscO Prominin PF05478.11 RUS86777.1 - 0.01 13.8 24.4 0.012 13.6 24.4 1.1 1 0 0 1 1 1 0 Prominin HOOK PF05622.12 RUS86777.1 - 0.01 14.0 29.2 0.032 12.4 29.2 1.7 1 1 0 1 1 1 0 HOOK protein V-SNARE PF05008.15 RUS86777.1 - 0.012 16.0 32.0 4.7 7.7 15.1 4.5 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Seryl_tRNA_N PF02403.22 RUS86777.1 - 0.013 15.8 35.8 1.4 9.2 14.5 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 RUS86777.1 - 0.013 15.9 18.5 1.8e+04 -4.1 18.5 3.9 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) Rootletin PF15035.6 RUS86777.1 - 0.014 15.4 12.8 0.028 14.5 12.8 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion MtrB PF05440.12 RUS86777.1 - 0.014 15.8 11.8 1.9e+03 -0.7 11.8 4.0 1 1 0 1 1 0 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF5344 PF17279.2 RUS86777.1 - 0.014 15.9 27.7 6.7 7.4 1.6 4.8 1 1 4 5 5 5 0 Family of unknown function (DUF5344) Tup_N PF08581.10 RUS86777.1 - 0.014 15.7 19.2 0.59 10.5 7.1 2.4 1 1 1 2 2 2 0 Tup N-terminal Nup88 PF10168.9 RUS86777.1 - 0.015 13.2 28.8 0.11 10.3 28.8 2.2 1 1 0 1 1 1 0 Nuclear pore component GAS PF13851.6 RUS86777.1 - 0.015 14.6 31.4 0.031 13.6 31.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOAR PF16533.5 RUS86777.1 - 0.015 15.2 19.5 1.7 8.7 7.0 3.4 1 1 1 2 2 2 0 STIM1 Orai1-activating region Streptin-Immun PF11083.8 RUS86777.1 - 0.015 15.6 17.0 3.8 8.0 2.1 3.7 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4795 PF16043.5 RUS86777.1 - 0.017 14.7 33.7 0.15 11.6 33.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PI3K_P85_iSH2 PF16454.5 RUS86777.1 - 0.017 14.7 27.2 0.39 10.3 12.4 3.0 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Perilipin PF03036.16 RUS86777.1 - 0.018 14.1 8.5 0.46 9.4 1.6 2.1 1 1 1 2 2 2 0 Perilipin family P4Ha_N PF08336.11 RUS86777.1 - 0.018 15.1 23.3 1.8e+04 -8.9 23.3 4.2 1 1 0 1 1 0 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FapA PF03961.13 RUS86777.1 - 0.019 13.6 36.2 0.26 9.8 16.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A HemX PF04375.14 RUS86777.1 - 0.019 14.3 17.4 0.28 10.4 6.7 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MutS_IV PF05190.18 RUS86777.1 - 0.02 15.3 24.8 1.8e+04 -8.9 24.8 3.9 1 1 0 1 1 0 0 MutS family domain IV Fib_alpha PF08702.10 RUS86777.1 - 0.02 15.0 29.5 5.4 7.2 29.5 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2802 PF10975.8 RUS86777.1 - 0.021 14.9 14.6 1.8e+04 -5.2 14.6 5.1 1 1 0 1 1 0 0 Protein of unknown function (DUF2802) LPP PF04728.13 RUS86777.1 - 0.022 15.1 26.3 4.6 7.7 1.9 4.1 1 1 3 4 4 4 0 Lipoprotein leucine-zipper CCDC144C PF14915.6 RUS86777.1 - 0.023 13.8 27.5 0.036 13.2 27.5 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4164 PF13747.6 RUS86777.1 - 0.023 14.9 15.6 17 5.8 15.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3958 PF13125.6 RUS86777.1 - 0.026 14.7 22.2 3.7 7.8 1.9 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3958) TraF_2 PF13729.6 RUS86777.1 - 0.029 13.7 24.2 1.8e+04 -5.4 24.2 3.0 1 1 0 1 1 0 0 F plasmid transfer operon, TraF, protein DUF948 PF06103.11 RUS86777.1 - 0.03 14.6 25.6 1.8e+04 -4.8 25.6 3.2 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) DUF489 PF04356.12 RUS86777.1 - 0.035 14.1 16.3 1.6 8.7 8.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) PEARLI-4 PF05278.12 RUS86777.1 - 0.037 13.6 26.3 1.6 8.2 12.1 2.3 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) CheZ PF04344.13 RUS86777.1 - 0.043 13.7 14.8 0.72 9.7 4.7 2.1 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Occludin_ELL PF07303.13 RUS86777.1 - 0.044 14.5 31.1 0.47 11.2 13.6 2.3 1 1 1 2 2 2 0 Occludin homology domain Spectrin PF00435.21 RUS86777.1 - 0.044 14.3 21.4 4.9 7.7 21.4 2.3 1 1 0 1 1 1 0 Spectrin repeat TRPM_tetra PF16519.5 RUS86777.1 - 0.047 13.8 21.0 1.8e+04 -7.2 21.0 3.9 1 1 0 1 1 0 0 Tetramerisation domain of TRPM DLP_helical PF18709.1 RUS86777.1 - 0.048 12.9 21.6 1.1 8.3 4.6 2.9 1 1 2 3 3 3 0 Dynamin-like helical domain WASH_WAHD PF11945.8 RUS86777.1 - 0.058 12.9 28.3 4.2 6.8 5.7 3.6 1 1 1 2 2 1 0 WAHD domain of WASH complex PI_PP_I PF18363.1 RUS86777.1 - 0.059 13.5 23.2 3.2 8.0 3.4 3.1 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain Dynamitin PF04912.14 RUS86777.1 - 0.065 12.6 31.2 1.1e+02 1.9 31.2 3.6 1 1 0 1 1 1 0 Dynamitin bZIP_Maf PF03131.17 RUS86777.1 - 0.065 13.8 12.3 10 6.7 1.8 3.2 1 1 1 2 2 2 0 bZIP Maf transcription factor TLE_N PF03920.15 RUS86777.1 - 0.071 13.2 29.7 4 7.5 1.6 4.3 1 1 6 7 7 7 0 Groucho/TLE N-terminal Q-rich domain DUF4315 PF14193.6 RUS86777.1 - 0.073 13.1 48.1 3.6 7.7 4.7 5.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4315) DUF4298 PF14131.6 RUS86777.1 - 0.076 13.0 24.9 5 7.2 1.5 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) Erp_C PF06780.11 RUS86777.1 - 0.076 13.0 33.4 7.5 6.6 4.1 5.0 1 1 1 2 2 1 0 Erp protein C-terminus Med9 PF07544.13 RUS86777.1 - 0.077 13.1 40.9 1.8e+04 -18.4 40.9 5.6 1 1 0 1 1 0 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GPO PF05929.11 RUS86777.1 - 0.089 12.4 19.9 4 7.0 8.7 2.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1638 PF07796.11 RUS86777.1 - 0.094 12.8 6.3 32 4.5 6.3 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1638) CC2-LZ PF16516.5 RUS86777.1 - 0.1 13.0 28.5 4.3 7.8 5.2 3.1 1 1 1 2 2 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GTP-bdg_M PF16360.5 RUS86777.1 - 0.11 13.1 36.1 9.2 6.9 2.2 5.3 1 1 6 7 7 7 0 GTP-binding GTPase Middle Region IDO PF01231.18 RUS86777.1 - 0.11 11.3 14.9 1.8e+03 -2.6 14.9 3.0 1 1 0 1 1 0 0 Indoleamine 2,3-dioxygenase DHC_N2 PF08393.13 RUS86777.1 - 0.11 11.6 22.6 0.43 9.6 22.6 1.9 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 MAD PF05557.13 RUS86777.1 - 0.12 10.7 24.9 0.36 9.1 24.9 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein FliD_C PF07195.12 RUS86777.1 - 0.13 11.7 32.2 2.2 7.6 8.9 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Zwint PF15556.6 RUS86777.1 - 0.13 11.8 22.2 0.91 9.0 22.2 2.6 1 1 0 1 1 1 0 ZW10 interactor LIF_OSM PF01291.17 RUS86777.1 - 0.13 12.4 19.5 1.4e+04 -4.0 19.5 3.2 1 1 0 1 1 0 0 LIF / OSM family Myosin_tail_1 PF01576.19 RUS86777.1 - 0.14 9.9 27.4 0.26 9.1 27.4 1.5 1 1 0 1 1 1 0 Myosin tail TBK1_CCD1 PF18394.1 RUS86777.1 - 0.15 11.6 27.4 1.8e+04 -7.8 27.4 4.1 1 1 0 1 1 0 0 TANK-binding kinase 1 coiled-coil domain 1 SHE3 PF17078.5 RUS86777.1 - 0.15 11.7 29.0 1.1 8.9 29.0 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CALCOCO1 PF07888.11 RUS86777.1 - 0.16 10.8 23.2 0.35 9.7 12.1 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CorA PF01544.18 RUS86777.1 - 0.19 11.0 14.3 2.1 7.6 14.3 2.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 RUS86777.1 - 0.19 11.2 34.0 0.45 9.9 34.0 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4446 PF14584.6 RUS86777.1 - 0.21 11.6 23.2 1.6e+04 -4.3 23.2 2.9 1 1 0 1 1 0 0 Protein of unknown function (DUF4446) DUF812 PF05667.11 RUS86777.1 - 0.21 10.4 31.2 0.27 10.1 31.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4472 PF14739.6 RUS86777.1 - 0.26 12.0 16.1 1.4 9.7 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Tweety PF04906.13 RUS86777.1 - 0.27 9.9 13.9 0.92 8.1 4.6 2.0 1 1 1 2 2 2 0 Tweety V_ATPase_I PF01496.19 RUS86777.1 - 0.28 9.1 18.3 2.6 5.8 18.3 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-K PF11802.8 RUS86777.1 - 0.31 10.6 33.0 2.7 7.5 33.0 1.9 1 1 0 1 1 1 0 Centromere-associated protein K Phage_GP20 PF06810.11 RUS86777.1 - 0.31 10.8 45.3 3.3 7.5 14.3 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4618 PF15397.6 RUS86777.1 - 0.31 10.4 27.9 3.4 7.0 11.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Cep57_CLD_2 PF14197.6 RUS86777.1 - 0.32 11.1 17.5 1.8e+04 -6.2 17.5 5.0 1 1 0 1 1 0 0 Centrosome localisation domain of PPC89 YgaB PF14182.6 RUS86777.1 - 0.34 11.3 32.8 23 5.5 8.2 4.3 1 1 2 3 3 2 0 YgaB-like protein Borrelia_P83 PF05262.11 RUS86777.1 - 0.34 9.3 31.9 8.7 4.7 9.0 3.2 1 1 1 2 2 2 0 Borrelia P83/100 protein Tmemb_cc2 PF10267.9 RUS86777.1 - 0.35 10.0 23.6 84 2.1 23.6 3.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3552 PF12072.8 RUS86777.1 - 0.36 10.2 33.7 7.1e+03 -3.8 33.7 2.2 1 1 0 1 1 0 0 Domain of unknown function (DUF3552) DUF2968 PF11180.8 RUS86777.1 - 0.36 10.4 15.1 2.1 7.9 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 RUS86777.1 - 0.36 11.0 19.4 4 7.6 19.4 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 RUS86777.1 - 0.37 9.6 23.7 28 3.5 23.7 2.9 1 1 0 1 1 1 0 LMBR1-like membrane protein BLOC1S3 PF15753.5 RUS86777.1 - 0.4 10.8 20.7 4.1 7.5 3.3 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Serine_rich PF08824.10 RUS86777.1 - 0.41 10.6 21.1 1.6e+02 2.2 21.1 3.1 1 1 0 1 1 1 0 Serine rich protein interaction domain Prefoldin PF02996.17 RUS86777.1 - 0.41 10.6 39.6 7.8 6.4 5.7 4.0 1 1 3 4 4 4 0 Prefoldin subunit MT PF12777.7 RUS86777.1 - 0.44 9.5 25.9 2.4 7.1 6.0 3.0 1 1 2 3 3 3 0 Microtubule-binding stalk of dynein motor Dynactin PF12455.8 RUS86777.1 - 0.47 9.7 19.2 2.1 7.5 7.1 2.1 1 1 1 2 2 2 0 Dynein associated protein ECM11 PF15463.6 RUS86777.1 - 0.63 10.6 26.2 25 5.4 2.8 4.7 1 1 3 4 4 4 0 Extracellular mutant protein 11 Syntaxin_2 PF14523.6 RUS86777.1 - 0.68 10.3 37.6 3.5e+03 -1.6 37.6 2.7 1 1 0 1 1 0 0 Syntaxin-like protein GrpE PF01025.19 RUS86777.1 - 0.81 9.3 22.8 8.4 6.0 5.1 3.0 1 1 1 2 2 2 0 GrpE Swi5 PF07061.11 RUS86777.1 - 0.82 9.8 34.2 1.3e+03 -0.4 16.8 3.4 1 1 1 2 2 0 0 Swi5 ATG16 PF08614.11 RUS86777.1 - 0.82 9.9 23.8 1.6 8.9 11.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 RUS86777.1 - 1.1 8.6 26.4 1.1 8.5 14.2 2.0 1 1 1 2 2 2 0 Rabaptin-like protein Mce4_CUP1 PF11887.8 RUS86777.1 - 1.2 8.5 6.7 3.6 7.0 6.7 1.8 1 1 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Effector_1 PF04518.12 RUS86777.1 - 1.3 8.0 19.0 4.6 6.2 2.4 2.6 1 1 2 3 3 3 0 Effector from type III secretion system GldM_N PF12081.8 RUS86777.1 - 1.4 9.0 28.4 17 5.4 28.4 2.4 1 1 0 1 1 1 0 GldM N-terminal domain SlyX PF04102.12 RUS86777.1 - 1.4 9.6 17.3 1.8e+04 -4.1 17.3 3.6 1 1 0 1 1 0 0 SlyX Sec3_C PF09763.9 RUS86777.1 - 1.4 7.2 22.3 4.8e+02 -1.2 22.3 2.4 1 1 0 1 1 1 0 Exocyst complex component Sec3 5_nucleotid PF05761.14 RUS86777.1 - 1.4 7.7 15.9 3.5 6.4 5.2 2.0 1 1 1 2 2 2 0 5' nucleotidase family Peptidase_M75 PF09375.10 RUS86777.1 - 1.5 8.3 20.6 1.8e+04 -7.3 20.6 3.9 1 1 0 1 1 0 0 Imelysin Sas10_Utp3 PF04000.15 RUS86777.1 - 1.5 9.5 26.4 1.8e+04 -11.8 26.4 4.3 1 1 0 1 1 0 0 Sas10/Utp3/C1D family ZapD PF07072.11 RUS86777.1 - 1.5 8.6 20.0 9.5e+03 -3.9 20.0 2.7 1 1 0 1 1 0 0 Cell division protein ZapB PF06005.12 RUS86777.1 - 1.5 9.3 26.0 7.5 7.1 10.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB PTRF_SDPR PF15237.6 RUS86777.1 - 1.8 8.1 34.6 5.8 6.5 22.6 2.4 1 1 1 2 2 2 0 PTRF/SDPR family G10 PF01125.17 RUS86777.1 - 1.8 8.3 17.2 1.8e+04 -5.2 17.2 3.5 1 1 0 1 1 0 0 G10 protein DUF2130 PF09903.9 RUS86777.1 - 2 7.6 33.6 1.8e+04 -7.4 33.6 2.9 1 1 0 1 1 0 0 Uncharacterized protein conserved in bacteria (DUF2130) Atg14 PF10186.9 RUS86777.1 - 2 7.4 35.1 11 5.0 35.1 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1690 PF07956.11 RUS86777.1 - 2 8.8 27.4 8.8e+03 -3.0 27.4 2.4 1 1 0 1 1 0 0 Protein of Unknown function (DUF1690) AIP3 PF03915.13 RUS86777.1 - 2.1 7.3 32.6 5.5 6.0 32.6 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 DUF4988 PF16378.5 RUS86777.1 - 2.5 7.7 22.8 14 5.3 3.5 3.7 1 1 2 3 3 3 0 Domain of unknown function DUF4559 PF15112.6 RUS86777.1 - 2.5 7.7 34.5 15 5.2 3.8 4.2 1 1 1 2 2 1 0 Domain of unknown function (DUF4559) DUF2433 PF10360.9 RUS86777.1 - 2.5 8.2 15.4 3.7e+03 -2.0 15.4 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF2433) DUF4200 PF13863.6 RUS86777.1 - 2.6 8.5 35.7 1.8e+03 -0.7 35.7 2.4 1 1 0 1 1 0 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 RUS86777.1 - 2.6 8.1 28.6 8.3 6.5 28.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Com_YlbF PF06133.11 RUS86777.1 - 3 8.5 23.4 1.8e+04 -6.2 23.4 3.1 1 1 0 1 1 0 0 Control of competence regulator ComK, YlbF/YmcA CdvA PF18822.1 RUS86777.1 - 3.4 7.5 38.8 1.8e+04 -7.9 38.8 3.9 1 1 0 1 1 0 0 CdvA-like coiled-coil domain Cortex-I_coil PF09304.10 RUS86777.1 - 3.6 7.9 25.6 15 5.8 11.2 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil FmiP_Thoc5 PF09766.9 RUS86777.1 - 3.7 6.7 34.5 23 4.1 14.3 2.9 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 DUF4337 PF14235.6 RUS86777.1 - 3.8 7.6 24.1 1.8e+04 -5.2 24.1 2.7 1 1 0 1 1 0 0 Domain of unknown function (DUF4337) DUF3216 PF11505.8 RUS86777.1 - 3.9 7.7 29.0 1.2e+03 -0.3 11.0 4.7 1 1 1 2 2 0 0 Protein of unknown function (DUF3216) DivIVA PF05103.13 RUS86777.1 - 5.9 7.0 23.0 32 4.6 5.9 3.0 1 1 1 2 2 2 0 DivIVA protein PIEZO PF15917.5 RUS86777.1 - 6.7 6.1 37.9 1.8e+04 -19.2 37.9 4.3 1 1 0 1 1 0 0 Piezo Flagellin_N PF00669.20 RUS86777.1 - 6.9 6.8 19.4 14 5.8 7.7 2.6 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Phage_HK97_TLTM PF06120.11 RUS86777.1 - 9 5.4 32.9 54 2.8 32.9 2.0 1 1 0 1 1 1 0 Tail length tape measure protein Ntox28 PF15605.6 RUS86777.1 - 9 6.6 18.8 39 4.6 5.1 3.1 1 1 3 4 4 4 0 Bacterial toxin 28 DUF773 PF05600.12 RUS86777.1 - 9.5 4.8 30.0 9.6 4.8 12.0 2.1 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Antifungal_pept PF11410.8 RUS86780.1 - 0.15 12.0 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 Antifungal peptide ABC_membrane PF00664.23 RUS86781.1 - 7.9e-54 183.1 25.3 5.5e-39 134.5 7.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS86781.1 - 7.3e-44 149.6 0.1 3e-30 105.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS86781.1 - 1.4e-06 28.4 0.2 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS86781.1 - 5.4e-06 26.0 0.0 0.31 10.5 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS86781.1 - 0.02 15.0 0.2 0.061 13.4 0.2 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS86781.1 - 0.13 12.1 0.2 0.34 10.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 RUS86781.1 - 0.15 12.1 0.4 0.36 10.9 0.4 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Astacin PF01400.24 RUS86782.1 - 4.8e-62 209.0 0.0 6.5e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 RUS86782.1 - 2.3e-32 112.1 0.0 3.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Nucleos_tra2_C PF07662.13 RUS86784.1 - 4.2e-64 216.2 4.6 4.2e-64 216.2 4.6 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 RUS86784.1 - 2.4e-20 72.9 0.2 2.4e-20 72.9 0.2 3.4 3 1 1 4 4 4 1 Na+ dependent nucleoside transporter N-terminus AWPM-19 PF05512.11 RUS86784.1 - 0.036 14.3 1.1 0.036 14.3 1.1 2.6 2 0 0 2 2 2 0 AWPM-19-like family DUF3989 PF13150.6 RUS86784.1 - 0.075 12.8 2.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) DUF417 PF04224.12 RUS86784.1 - 0.89 9.1 5.4 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF417 Gate PF07670.14 RUS86784.1 - 3 8.2 15.9 4.4 7.6 9.8 3.6 3 1 1 4 4 4 0 Nucleoside recognition MerR_1 PF13411.6 RUS86786.1 - 1.8e-06 27.9 9.2 19 5.4 0.0 8.0 2 1 7 9 9 9 1 MerR HTH family regulatory protein Dis3l2_C_term PF17877.1 RUS86786.1 - 2.1e-06 27.9 6.5 0.65 10.4 0.1 4.8 1 1 3 4 4 4 3 DIS3-like exonuclease 2 C terminal AcetylCoA_hyd_C PF13336.6 RUS86786.1 - 0.0058 16.6 0.6 3.4 7.6 0.1 2.5 1 1 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain Porphyrn_cat_1 PF18206.1 RUS86786.1 - 0.35 11.5 20.7 10 6.8 0.9 5.3 2 1 6 8 8 8 0 Porphyranase catalytic subdomain 1 RVT_connect PF06815.13 RUS86786.1 - 1.1 9.6 20.8 3.4 8.0 0.2 6.7 2 2 6 8 8 8 0 Reverse transcriptase connection domain H_lectin PF09458.10 RUS86786.1 - 7.2 6.9 22.9 34 4.7 0.5 7.0 2 1 7 9 9 9 0 H-type lectin domain CdiI PF07262.11 RUS86787.1 - 0.074 12.8 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein Presenilin PF01080.17 RUS86788.1 - 0.52 9.0 3.8 0.51 9.0 3.8 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RUS86788.1 - 1.1 7.8 5.4 1.2 7.6 5.4 1.0 1 0 0 1 1 1 0 Macoilin family Opi1 PF08618.10 RUS86788.1 - 2 7.6 12.5 2.4 7.3 12.5 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DUF572 PF04502.13 RUS86788.1 - 5.1 6.6 10.2 6.3 6.3 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 RUS86788.1 - 7 5.4 11.2 8.7 5.1 11.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 RUS86788.1 - 8.1 6.2 15.9 10 5.9 15.9 1.2 1 0 0 1 1 1 0 SPX domain LPMO_10 PF03067.15 RUS86789.1 - 9.9e-25 88.3 0.9 1.2e-24 88.1 0.9 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Got1 PF04178.12 RUS86790.1 - 5.1e-36 123.5 18.4 8.8e-36 122.8 18.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family CrgA PF06781.12 RUS86790.1 - 1.9 8.6 5.0 1.8 8.7 1.2 2.5 3 0 0 3 3 3 0 Cell division protein CrgA 7tm_2 PF00002.24 RUS86791.1 - 1.7e-15 57.0 16.9 1.7e-15 57.0 16.9 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 RUS86791.1 - 0.18 12.2 4.1 0.56 10.6 4.1 1.9 1 0 0 1 1 1 0 Somatomedin B domain TcpE PF12648.7 RUS86791.1 - 1.3 9.6 6.0 0.43 11.1 1.3 2.4 2 0 0 2 2 2 0 TcpE family DUF4808 PF16066.5 RUS86792.1 - 9.8e-11 42.3 0.3 1.3e-10 41.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) Tmemb_9 PF05434.11 RUS86792.1 - 0.058 13.3 0.3 0.074 12.9 0.3 1.1 1 0 0 1 1 1 0 TMEM9 Mur_ligase_C PF02875.21 RUS86792.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain MoeA_C PF03454.15 RUS86793.1 - 0.12 12.6 0.1 5.1 7.4 0.0 2.9 3 1 1 4 4 4 0 MoeA C-terminal region (domain IV) TFIIIC_delta PF12657.7 RUS86793.1 - 0.15 12.0 0.8 14 5.5 0.1 2.7 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term CrgA PF06781.12 RUS86794.1 - 0.16 12.1 0.0 0.63 10.1 0.0 2.0 1 0 0 1 1 1 0 Cell division protein CrgA DUF3040 PF11239.8 RUS86794.1 - 0.23 11.8 5.7 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Glycophorin_A PF01102.18 RUS86794.1 - 1.4 9.2 3.4 4.8 7.5 0.7 2.6 2 1 0 2 2 2 0 Glycophorin A Guanylate_cyc PF00211.20 RUS86795.1 - 5.6e-61 205.3 0.0 1.3e-60 204.1 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS86795.1 - 4.6e-06 26.2 0.4 7.5e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pex24p PF06398.11 RUS86795.1 - 1.1 8.1 3.7 1.7 7.6 3.7 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3377 PF11857.8 RUS86795.1 - 1.2 9.1 3.9 2.5 8.1 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4798 PF16055.5 RUS86796.1 - 0.12 12.7 0.3 5.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4798) Phage_integrase PF00589.22 RUS86797.1 - 0.02 14.7 0.6 0.038 13.8 0.4 1.6 2 0 0 2 2 2 0 Phage integrase family EF-hand_8 PF13833.6 RUS86800.1 - 4e-08 33.0 1.6 8.5e-08 31.9 1.6 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS86800.1 - 2.2e-06 28.0 0.9 8.8e-06 26.1 0.9 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS86800.1 - 7e-06 25.2 1.2 1.7e-05 24.0 1.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS86800.1 - 0.004 17.0 1.3 0.0068 16.3 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 RUS86800.1 - 0.01 15.8 0.2 0.03 14.3 0.2 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 RUS86800.1 - 0.033 13.7 0.2 0.088 12.3 0.2 1.7 1 0 0 1 1 1 0 EF hand TFIIA PF03153.13 RUS86800.1 - 0.78 9.7 55.5 0.92 9.4 55.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TatD_DNase PF01026.21 RUS86801.1 - 3.3e-36 125.0 0.0 4.7e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase zf-CCHC PF00098.23 RUS86803.1 - 6.8e-06 25.9 12.0 0.0035 17.3 1.8 2.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS86803.1 - 0.04 13.7 7.6 0.042 13.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF3365 PF11845.8 RUS86804.1 - 0.045 14.1 1.9 0.15 12.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) zf-CCHC_4 PF14392.6 RUS86804.1 - 6.2 6.6 13.1 0.58 9.9 2.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 RUS86804.1 - 8.4 6.2 19.0 0.93 9.3 8.5 2.7 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Fibrinogen_C PF00147.18 RUS86805.1 - 1.1e-54 185.6 12.7 2.2e-54 184.6 11.2 1.9 1 1 1 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spectrin PF00435.21 RUS86805.1 - 0.023 15.2 0.9 0.81 10.2 0.2 2.3 2 0 0 2 2 2 0 Spectrin repeat CCDC53 PF10152.9 RUS86805.1 - 0.04 14.3 0.5 0.061 13.7 0.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex NPV_P10 PF05531.12 RUS86805.1 - 0.042 14.3 2.3 0.05 14.1 0.1 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 RUS86805.1 - 0.059 13.0 7.6 0.1 12.2 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 RUS86805.1 - 0.062 13.8 5.7 0.43 11.1 5.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DASH_Dad4 PF08650.10 RUS86805.1 - 0.092 12.7 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad4 FlaC_arch PF05377.11 RUS86805.1 - 0.15 12.4 4.3 0.68 10.4 0.4 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 RUS86805.1 - 0.42 10.9 5.0 0.76 10.1 5.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 RUS86805.1 - 0.46 10.8 5.3 0.15 12.4 1.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPW8 PF05659.11 RUS86805.1 - 0.48 10.1 4.7 0.26 11.0 0.8 2.3 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc42p PF11544.8 RUS86805.1 - 0.66 10.0 4.5 0.13 12.2 0.7 1.7 2 0 0 2 2 2 0 Spindle pole body component Spc42p Baculo_PEP_C PF04513.12 RUS86805.1 - 1.2 9.2 6.5 0.81 9.7 0.7 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 RUS86805.1 - 1.4 8.9 5.7 2.8 7.9 0.1 3.3 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ABC_tran_CTD PF16326.5 RUS86805.1 - 1.8 8.9 8.6 1.4 9.2 3.3 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain FliD_N PF02465.18 RUS86805.1 - 2 9.2 6.3 0.43 11.3 0.7 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Allexi_40kDa PF05549.11 RUS86805.1 - 2.1 7.8 5.8 0.79 9.2 1.3 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein UNC-50 PF05216.13 RUS86806.1 - 1 8.9 9.4 0.77 9.3 6.7 1.9 1 1 1 2 2 2 0 UNC-50 family UPF0020 PF01170.18 RUS86807.1 - 3.7e-13 49.6 0.0 1.3e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 RUS86807.1 - 3.3e-06 27.0 0.0 0.00059 19.6 0.0 2.5 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 RUS86807.1 - 6.4e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltr_RsmB-F PF01189.17 RUS86807.1 - 0.00083 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_11 PF08241.12 RUS86807.1 - 0.00084 19.9 0.0 0.0038 17.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS86807.1 - 0.0023 17.6 0.2 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MPS-4 PF17523.2 RUS86807.1 - 0.028 14.5 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 TRAP_alpha PF03896.16 RUS86808.1 - 0.017 14.4 11.0 0.024 13.9 11.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 RUS86808.1 - 0.038 12.1 33.4 0.051 11.7 33.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS86808.1 - 0.075 11.2 19.4 0.093 10.9 19.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS86808.1 - 0.11 10.7 14.6 0.15 10.3 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.10 RUS86808.1 - 0.3 11.8 25.8 0.49 11.1 25.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2796 PF10986.8 RUS86808.1 - 1.2 9.1 7.9 1.7 8.6 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RRN3 PF05327.11 RUS86808.1 - 1.3 7.5 18.1 1.6 7.2 18.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 RUS86808.1 - 1.4 7.2 16.7 1.8 6.9 16.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid_p PF12226.8 RUS86808.1 - 1.5 7.9 16.4 1.9 7.6 16.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TFIIA PF03153.13 RUS86808.1 - 1.7 8.5 19.9 1.9 8.4 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 RUS86808.1 - 2.8 7.8 9.8 3.5 7.4 9.8 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 RUS86808.1 - 3 7.2 7.2 3.9 6.8 7.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sigma70_ner PF04546.13 RUS86808.1 - 4.8 7.0 17.9 8.7 6.2 17.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 RUS86808.1 - 5 6.8 13.4 7.5 6.3 13.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Osteopontin PF00865.18 RUS86808.1 - 5 6.5 33.7 7.6 5.9 33.7 1.3 1 0 0 1 1 1 0 Osteopontin Myotub-related PF06602.14 RUS86809.1 - 2.1e-144 480.8 0.1 2.6e-144 480.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 RUS86809.1 - 3.7e-09 36.6 8.5 8.2e-09 35.5 8.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger DSPc PF00782.20 RUS86809.1 - 0.00064 19.6 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS86809.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS86809.1 - 0.093 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family MMR_HSR1 PF01926.23 RUS86810.1 - 2.6e-16 59.7 0.0 4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS86810.1 - 1.2e-05 25.3 0.0 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS86810.1 - 2.1e-05 24.2 0.0 0.005 16.4 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RUS86810.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 RUS86810.1 - 0.00096 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 RUS86810.1 - 0.0057 16.5 0.2 0.02 14.7 0.1 1.8 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 RUS86810.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 RUS86810.1 - 0.079 12.5 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.6 RUS86810.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 RUS86810.1 - 0.2 11.9 0.0 0.42 10.8 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cNMP_binding PF00027.29 RUS86813.1 - 6.4e-24 83.8 0.5 7.4e-20 70.8 0.1 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF4175 PF13779.6 RUS86813.1 - 0.032 12.1 0.7 0.53 8.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4175) NHL PF01436.21 RUS86814.1 - 5.3e-16 57.7 7.6 0.0017 18.3 0.0 5.4 5 0 0 5 5 5 4 NHL repeat zf-B_box PF00643.24 RUS86814.1 - 0.00028 21.0 9.0 0.00028 21.0 9.0 4.5 4 1 1 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS86814.1 - 0.018 15.0 15.2 0.07 13.2 15.2 2.1 1 0 0 1 1 1 0 RING-type zinc-finger APG6_N PF17675.1 RUS86814.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Pih1_fungal_CS PF18482.1 RUS86815.1 - 0.01 16.3 2.3 0.019 15.4 2.3 1.5 1 0 0 1 1 1 0 Fungal Pih1 CS domain RNA_pol_Rpb1_5 PF04998.17 RUS86815.1 - 0.13 11.6 0.4 0.15 11.5 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TMEM232 PF15877.5 RUS86816.1 - 2.7e-107 359.6 0.0 6.7e-79 266.0 0.0 2.1 2 0 0 2 2 2 2 Transmembrane protein family 232 Peptidase_M24 PF00557.24 RUS86818.1 - 3.8e-55 186.8 0.0 9.8e-55 185.5 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 RUS86818.1 - 2.3e-32 111.3 0.0 3.9e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Galactosyl_T PF01762.21 RUS86819.1 - 6.6e-36 124.0 0.0 9.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Rho_RNA_bind PF07497.12 RUS86819.1 - 0.083 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain UnbV_ASPIC PF07593.12 RUS86819.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV Galactosyl_T PF01762.21 RUS86820.1 - 1e-40 139.7 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase FBP_C PF16571.5 RUS86820.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Death PF00531.22 RUS86821.1 - 0.0021 18.2 5.4 0.0037 17.4 0.0 3.4 4 0 0 4 4 4 1 Death domain Sec5 PF15469.6 RUS86821.1 - 0.26 11.0 4.6 5.4 6.8 1.7 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 Spc7 PF08317.11 RUS86821.1 - 0.31 9.9 7.9 0.21 10.5 4.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 RUS86821.1 - 0.4 10.7 11.9 1.9 8.4 0.0 3.6 3 1 1 4 4 4 0 Prefoldin subunit Snapin_Pallidin PF14712.6 RUS86821.1 - 1.3 9.5 7.4 5.4 7.5 7.4 2.1 1 0 0 1 1 1 0 Snapin/Pallidin GAS PF13851.6 RUS86821.1 - 1.8 7.9 16.1 0.43 9.9 4.6 3.4 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 RUS86821.1 - 2.7 8.7 9.9 0.91 10.2 0.1 3.6 3 1 0 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 RUS86821.1 - 4.8 7.6 13.8 3.3 8.1 5.8 3.1 2 1 0 2 2 2 0 Fez1 Occludin_ELL PF07303.13 RUS86821.1 - 6.6 7.5 6.4 12 6.7 1.6 3.0 2 1 0 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.7 RUS86821.1 - 6.9 6.8 12.8 0.11 12.6 3.0 2.8 3 0 0 3 3 3 0 Tropomyosin like NYD-SP28_assoc PF14775.6 RUS86821.1 - 7.1 6.8 5.7 13 5.9 3.8 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Kelch_1 PF01344.25 RUS86822.1 - 2.5e-69 228.7 10.2 1.9e-14 53.0 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS86822.1 - 1.4e-37 126.8 4.1 4.7e-06 26.7 0.1 6.3 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 RUS86822.1 - 9.2e-31 106.0 2.5 2.5e-30 104.6 0.6 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS86822.1 - 7e-26 90.6 2.2 1.1e-25 90.0 2.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 RUS86822.1 - 4.3e-21 74.7 5.3 0.001 19.1 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS86822.1 - 2.3e-16 59.0 10.4 3.7e-06 26.7 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 RUS86822.1 - 8.5e-10 38.7 9.4 0.063 13.6 0.2 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF3342 PF11822.8 RUS86822.1 - 5.1e-06 26.6 3.7 9.6e-05 22.5 0.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) NopRA1 PF16201.5 RUS86822.1 - 0.047 13.3 0.6 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Varsurf_PPLC PF03490.13 RUS86822.1 - 0.2 11.6 0.6 6.7 6.7 0.0 3.1 4 0 0 4 4 3 0 Variant-surface-glycoprotein phospholipase C Kelch_5 PF13854.6 RUS86822.1 - 0.34 10.9 10.2 2.5 8.2 0.0 5.2 6 0 0 6 6 6 0 Kelch motif PQQ PF01011.21 RUS86822.1 - 2.2 8.4 6.8 16 5.6 0.7 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat Torsin PF06309.11 RUS86823.1 - 9.9e-48 161.4 1.9 6.2e-47 158.9 0.1 2.6 2 1 1 3 3 3 1 Torsin Pkinase PF00069.25 RUS86824.1 - 6.4e-40 137.2 0.0 1.2e-39 136.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86824.1 - 3.1e-24 85.7 0.0 4.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS86824.1 - 0.00012 21.6 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RUS86824.1 - 0.0033 16.3 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RUS86824.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RUS86824.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RUS86825.1 - 2.7e-42 145.0 0.0 4.7e-42 144.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86825.1 - 6.4e-24 84.6 0.0 9.5e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS86825.1 - 0.003 16.4 0.0 0.0077 15.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS86825.1 - 0.0032 16.8 0.0 0.0077 15.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 RUS86825.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.4 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 RUS86825.1 - 0.054 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RUS86825.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 RUS86826.1 - 0.00096 17.6 11.5 0.00096 17.6 11.5 2.1 2 0 0 2 2 2 2 CDC45-like protein DNA_pol_phi PF04931.13 RUS86826.1 - 0.11 10.6 102.6 0.36 8.9 42.3 2.2 2 0 0 2 2 2 0 DNA polymerase phi Cadherin PF00028.17 RUS86827.1 - 1.3e-85 282.0 8.8 1.1e-15 57.8 0.4 7.5 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS86827.1 - 7e-15 54.6 0.0 1.1e-11 44.3 0.0 4.9 4 1 0 4 4 4 1 Cadherin-like Cadherin_3 PF16184.5 RUS86827.1 - 0.0026 17.7 4.7 2.4 8.2 0.0 5.2 5 0 0 5 5 5 1 Cadherin-like Shisa PF13908.6 RUS86827.1 - 0.013 15.8 0.1 0.013 15.8 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF5383 PF17355.2 RUS86827.1 - 0.18 12.2 3.0 0.76 10.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5383) RCR PF12273.8 RUS86827.1 - 0.34 11.6 3.1 6.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pentapeptide_4 PF13599.6 RUS86828.1 - 5.6e-22 77.7 45.6 0.00023 21.3 3.0 7.0 1 1 5 6 6 6 6 Pentapeptide repeats (9 copies) DUF812 PF05667.11 RUS86829.1 - 0.0033 16.4 1.5 0.0048 15.9 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YabA PF06156.13 RUS86829.1 - 0.0044 17.6 2.6 0.068 13.8 0.3 2.7 2 0 0 2 2 2 1 Initiation control protein YabA ZapB PF06005.12 RUS86829.1 - 0.0076 16.7 1.0 1.3 9.5 0.3 2.5 2 0 0 2 2 2 1 Cell division protein ZapB Filament PF00038.21 RUS86829.1 - 0.015 14.9 0.9 0.03 13.9 0.2 1.7 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 RUS86829.1 - 0.046 13.8 1.4 0.046 13.8 1.4 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 RUS86829.1 - 0.046 14.3 0.3 0.29 11.7 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 RUS86829.1 - 0.061 13.9 2.1 2.3 8.9 0.1 2.4 2 0 0 2 2 2 0 SlyX Dynactin_p22 PF07426.11 RUS86829.1 - 0.087 12.7 1.6 1.5 8.7 0.1 2.6 2 1 0 2 2 2 0 Dynactin subunit p22 Spectrin PF00435.21 RUS86829.1 - 0.23 11.9 2.3 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Spectrin repeat Uds1 PF15456.6 RUS86829.1 - 0.27 11.4 2.7 0.55 10.4 0.7 2.3 1 1 2 3 3 3 0 Up-regulated During Septation HAUS-augmin3 PF14932.6 RUS86829.1 - 0.66 9.5 4.3 1.6 8.3 0.3 2.7 2 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF4200 PF13863.6 RUS86829.1 - 0.79 10.1 4.6 0.27 11.6 0.9 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ADIP PF11559.8 RUS86829.1 - 2.8 8.0 6.6 2.6 8.1 1.1 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SSF PF00474.17 RUS86831.1 - 3.8e-09 35.9 20.1 3.8e-09 35.9 20.1 2.8 3 0 0 3 3 3 2 Sodium:solute symporter family HCMV_UL124 PF17609.2 RUS86831.1 - 0.15 12.2 0.0 0.89 9.7 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function FCH PF00611.23 RUS86832.1 - 7.8e-13 48.5 0.9 7.8e-13 48.5 0.9 3.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain tRNA_m1G_MT PF01746.21 RUS86832.1 - 0.0038 17.0 0.2 0.0064 16.2 0.2 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Myb_DNA-bind_7 PF15963.5 RUS86832.1 - 1 9.3 6.7 0.32 10.9 0.8 2.6 2 0 0 2 2 2 0 Myb DNA-binding like DUF4778 PF16008.5 RUS86832.1 - 6.2 6.8 11.5 3.7 7.5 8.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4778) V_ATPase_I PF01496.19 RUS86832.1 - 7.4 4.3 9.6 9.7 4.0 9.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec3_C PF09763.9 RUS86833.1 - 2.9e-130 435.8 28.4 4.6e-96 322.8 8.4 2.4 3 0 0 3 3 3 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 RUS86833.1 - 3.7e-20 71.8 0.4 1e-19 70.4 0.4 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH KNTase_C PF07827.11 RUS86833.1 - 0.0056 16.5 0.2 0.069 13.0 0.1 2.7 2 0 0 2 2 2 1 KNTase C-terminal domain Dus PF01207.17 RUS86833.1 - 0.013 14.7 0.0 0.042 12.9 0.0 1.9 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TSNAXIP1_N PF15739.5 RUS86833.1 - 0.2 12.1 8.7 0.73 10.2 0.0 4.1 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus WD40 PF00400.32 RUS86834.1 - 3.7e-44 147.8 20.1 1.9e-07 31.7 0.6 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86834.1 - 2.4e-06 27.8 0.8 0.47 10.8 0.0 5.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS86834.1 - 0.0002 20.2 1.1 0.013 14.2 0.4 2.8 1 1 1 2 2 2 2 Nucleoporin Nup120/160 End_tail_spike PF12219.8 RUS86834.1 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Catalytic domain of bacteriophage endosialidase BBS2_Mid PF14783.6 RUS86834.1 - 0.02 14.9 0.0 0.82 9.7 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 RUS86834.1 - 0.059 13.1 1.3 3.3 7.4 0.1 3.1 1 1 3 4 4 4 0 TUP1-like enhancer of split Ank_2 PF12796.7 RUS86835.1 - 5.5e-39 132.6 7.6 9.5e-14 51.8 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS86835.1 - 2.6e-34 117.1 6.7 1.2e-09 38.5 0.3 7.7 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS86835.1 - 5.9e-31 105.5 11.6 4.6e-07 30.0 0.1 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RUS86835.1 - 4.9e-30 100.2 6.8 7.1e-05 22.9 0.0 9.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS86835.1 - 1.9e-25 88.6 9.5 8.5e-09 35.5 0.1 7.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS86835.1 - 4e-08 33.5 0.1 9.4e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 SOCS box TED_complement PF07678.14 RUS86836.1 - 7.1e-101 337.3 0.0 1.2e-100 336.6 0.0 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 RUS86836.1 - 6.3e-32 110.8 5.2 7.5e-30 104.1 1.7 3.2 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 RUS86836.1 - 5.6e-28 96.6 0.5 5.6e-28 96.6 0.5 3.2 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 RUS86836.1 - 1.7e-24 86.4 0.5 6e-24 84.6 0.1 2.3 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG3 PF17791.1 RUS86836.1 - 1.1e-18 67.3 0.8 1.7e-17 63.5 0.1 2.8 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 RUS86836.1 - 3.9e-18 65.7 0.0 2.1e-17 63.4 0.0 2.4 1 0 0 1 1 1 1 MG2 domain Omp28 PF11551.8 RUS86836.1 - 0.02 14.7 0.9 5.4 6.8 0.1 3.1 2 0 0 2 2 2 0 Outer membrane protein Omp28 Fe-ADH PF00465.19 RUS86836.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase VirE3 PF06661.11 RUS86836.1 - 0.04 13.2 0.2 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 VirE3 MG4 PF17789.1 RUS86836.1 - 0.45 10.7 6.5 0.86 9.8 0.9 4.2 4 1 1 5 5 5 0 Macroglobulin domain MG4 STELLO PF03385.17 RUS86837.1 - 6.7e-30 104.2 0.2 7.7e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 STELLO glycosyltransferases E1_DerP2_DerF2 PF02221.15 RUS86839.1 - 9.2e-09 35.8 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 ML domain YL1 PF05764.13 RUS86839.1 - 0.038 14.1 14.0 0.046 13.8 14.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RUS86839.1 - 0.58 8.4 11.3 0.7 8.1 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RUS86839.1 - 2.5 7.4 20.4 3.3 7.1 20.4 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 RUS86839.1 - 8.5 5.0 10.2 11 4.6 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TLP-20 PF06088.11 RUS86839.1 - 9.5 6.1 12.1 26 4.6 12.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SK_channel PF03530.14 RUS86840.1 - 5.5e-28 97.3 1.6 5.5e-28 97.3 1.6 2.3 2 1 1 3 3 3 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 RUS86840.1 - 1.3e-14 53.9 5.0 1.3e-14 53.9 5.0 2.6 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RUS86840.1 - 0.00015 21.1 11.3 0.00087 18.6 11.3 2.0 1 1 0 1 1 1 1 Ion transport protein CaMBD PF02888.16 RUS86840.1 - 0.0034 17.5 1.6 0.0034 17.5 1.6 1.8 2 0 0 2 2 2 1 Calmodulin binding domain Lig_chan PF00060.26 RUS86840.1 - 0.0053 16.6 1.8 0.0053 16.6 1.8 2.6 2 1 1 3 3 3 1 Ligand-gated ion channel IRK PF01007.20 RUS86840.1 - 0.046 13.5 1.2 0.15 11.9 1.2 2.0 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Wzy_C PF04932.15 RUS86840.1 - 0.049 13.3 2.3 7.5 6.2 0.1 2.5 2 1 0 2 2 2 0 O-Antigen ligase Phage_holin_3_3 PF16083.5 RUS86840.1 - 0.051 13.7 3.2 0.054 13.6 0.0 2.7 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III CrgA PF06781.12 RUS86840.1 - 2.3 8.3 6.1 2.2 8.4 0.4 3.2 2 1 1 3 3 3 0 Cell division protein CrgA Ribosomal_L36 PF00444.18 RUS86843.1 - 9.9e-10 38.5 1.8 2.5e-09 37.2 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 Transglut_N PF00868.20 RUS86844.1 - 1.5e-34 118.9 0.7 2.7e-28 98.7 0.1 3.8 2 1 0 2 2 2 2 Transglutaminase family Transglut_core PF01841.19 RUS86844.1 - 4e-09 36.9 0.2 8.3e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 RUS86844.1 - 4.5e-08 33.2 0.0 0.002 18.2 0.0 2.8 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain DUF11 PF01345.18 RUS86844.1 - 0.0075 16.6 0.2 6.8 7.1 0.0 3.6 3 2 0 3 3 3 1 Domain of unknown function DUF11 Fn3-like PF14310.6 RUS86844.1 - 0.1 12.7 0.1 82 3.4 0.0 3.6 2 1 1 3 3 3 0 Fibronectin type III-like domain Transglut_N PF00868.20 RUS86845.1 - 3.9e-33 114.3 0.0 1.2e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase family Transglut_core PF01841.19 RUS86845.1 - 2.7e-16 60.0 0.1 5.6e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 RUS86845.1 - 0.013 15.6 0.0 0.048 13.8 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain CENP-Q PF13094.6 RUS86845.1 - 0.065 13.4 4.2 0.11 12.6 4.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IMD PF08397.11 RUS86846.1 - 3.1e-73 245.8 4.9 3.1e-73 245.8 4.9 1.5 2 0 0 2 2 2 1 IRSp53/MIM homology domain RRF PF01765.19 RUS86846.1 - 0.064 13.2 1.7 0.12 12.3 1.7 1.4 1 0 0 1 1 1 0 Ribosome recycling factor FAA_hydro_N_2 PF18288.1 RUS86846.1 - 0.35 11.3 1.8 8.5 6.9 0.2 3.3 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Syntaxin-6_N PF09177.11 RUS86846.1 - 8.8 7.0 6.2 19 5.9 2.7 3.3 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Sld5 PF05916.11 RUS86847.1 - 1e-20 74.2 0.4 1.6e-20 73.5 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein RPAP1_N PF08621.10 RUS86847.1 - 0.11 12.3 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF3736 PF12540.8 RUS86848.1 - 2.6e-06 27.6 7.5 2.6e-06 27.6 7.5 5.0 4 3 0 4 4 4 1 Protein of unknown function (DUF3736) MTBP_N PF14918.6 RUS86849.1 - 5.3e-05 22.8 2.0 5.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 MDM2-binding Phasin_2 PF09361.10 RUS86849.1 - 5.9 7.2 11.2 0.35 11.2 2.0 3.0 3 0 0 3 3 3 0 Phasin protein OmpH PF03938.14 RUS86849.1 - 8.6 6.7 8.9 50 4.2 4.7 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RVT_1 PF00078.27 RUS86850.1 - 1.3e-46 158.9 0.5 2.1e-46 158.2 0.5 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MADF_DNA_bdg PF10545.9 RUS86850.1 - 5.8 7.3 11.3 7.6 6.9 6.5 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Tcf25 PF04910.14 RUS86851.1 - 4.8e-94 315.3 0.0 6.4e-94 314.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 AP3D1 PF06375.11 RUS86851.1 - 2.1 8.6 14.5 4.6 7.5 14.5 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 EamA PF00892.20 RUS86852.1 - 0.003 17.7 12.5 0.0045 17.1 12.5 1.3 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 RUS86852.1 - 0.012 15.7 1.5 0.02 14.9 1.5 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 Ank_2 PF12796.7 RUS86853.1 - 1.1e-57 192.6 3.8 3e-12 46.9 0.1 6.6 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS86853.1 - 3.3e-36 119.2 7.7 0.00067 19.9 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.6 RUS86853.1 - 1.5e-34 117.9 6.0 1.2e-06 28.9 0.0 7.5 4 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 RUS86853.1 - 1.6e-30 104.2 16.5 5.4e-06 26.6 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 RUS86853.1 - 2.3e-28 97.9 8.4 3.3e-06 27.3 0.1 8.0 3 2 4 8 8 8 8 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS86853.1 - 3.9e-09 36.7 0.3 9.4e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 SOCS box UPF0172 PF03665.13 RUS86854.1 - 1.9e-35 122.7 1.3 2.1e-35 122.5 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF5003 PF16394.5 RUS86854.1 - 0.061 12.5 0.3 0.074 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Ras PF00071.22 RUS86855.1 - 7.3e-21 74.4 0.1 1.2e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS86855.1 - 0.002 18.3 0.2 0.057 13.6 0.2 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RUS86855.1 - 0.026 14.0 0.0 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS86855.1 - 0.11 12.0 3.0 0.38 10.3 0.5 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Tubulin PF00091.25 RUS86856.1 - 2.8e-69 233.3 0.0 4.6e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS86856.1 - 2.7e-43 147.2 0.1 4.2e-43 146.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS86856.1 - 1.3e-05 25.5 0.0 3.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS86856.1 - 0.0066 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RUS86856.1 - 0.015 14.5 0.1 0.033 13.4 0.0 1.5 2 0 0 2 2 2 0 Tubulin like S6OS1 PF15676.5 RUS86858.1 - 0.0045 15.5 4.9 0.006 15.1 4.9 1.1 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family MIF4G_like_2 PF09090.11 RUS86858.1 - 0.02 14.4 9.2 0.036 13.5 9.1 1.4 1 1 0 1 1 1 0 MIF4G like CLZ PF16526.5 RUS86858.1 - 0.027 14.8 9.4 1.1 9.7 1.3 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1281 PF06924.11 RUS86858.1 - 0.13 11.8 0.1 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Eapp_C PF10238.9 RUS86858.1 - 0.31 11.1 4.5 1.2 9.2 4.5 1.8 1 1 0 1 1 1 0 E2F-associated phosphoprotein MecA PF05389.12 RUS86858.1 - 0.37 10.4 6.9 1 9.0 6.8 1.7 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) V_ATPase_I PF01496.19 RUS86858.1 - 0.5 8.2 3.7 0.63 7.9 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIG-U PF06728.13 RUS86859.1 - 1.2e-104 350.4 38.8 1.5e-104 350.2 38.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF321 PF03778.13 RUS86859.1 - 0.018 14.7 0.1 0.051 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF321) NTF2 PF02136.20 RUS86860.1 - 1.2e-28 100.1 0.1 1.3e-28 100.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 RUS86860.1 - 0.022 15.1 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cadherin PF00028.17 RUS86861.1 - 6.5e-14 52.1 9.4 0.00078 19.8 0.3 5.7 4 2 1 5 5 5 5 Cadherin domain DUF11 PF01345.18 RUS86861.1 - 0.0093 16.2 0.1 0.45 10.9 0.3 3.1 3 1 0 3 3 3 1 Domain of unknown function DUF11 MFS_1 PF07690.16 RUS86862.1 - 1.4e-08 34.1 29.4 5.3e-08 32.2 29.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 RUS86862.1 - 0.00032 20.4 6.2 0.00032 20.4 6.2 2.3 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 zf-CCHC PF00098.23 RUS86863.1 - 6.2e-06 26.0 3.4 1e-05 25.4 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS86863.1 - 0.00031 20.5 3.3 0.00055 19.7 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS86863.1 - 0.0032 17.4 0.2 0.01 15.8 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS86863.1 - 0.026 14.2 1.7 0.05 13.3 1.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger FUSC PF04632.12 RUS86864.1 - 0.33 9.4 3.8 0.44 9.0 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SET PF00856.28 RUS86866.1 - 4e-17 63.1 0.0 2.3e-16 60.6 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 RUS86866.1 - 0.049 14.3 0.0 4.2 8.1 0.0 2.6 2 0 0 2 2 2 0 SAF domain LRR_8 PF13855.6 RUS86868.1 - 3.3e-17 62.0 17.5 6e-07 29.1 5.7 4.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RUS86868.1 - 1e-13 51.2 24.4 1.5e-06 28.4 1.8 5.1 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) B3_4 PF03483.17 RUS86868.1 - 2.9e-07 30.3 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain LRR_9 PF14580.6 RUS86868.1 - 9.1e-06 25.3 7.5 0.012 15.1 0.6 2.8 1 1 0 2 2 2 2 Leucine-rich repeat Rab_eff_C PF04698.12 RUS86868.1 - 0.045 12.1 0.0 0.066 11.5 0.0 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus SpoVG PF04026.12 RUS86868.1 - 0.12 12.5 0.1 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 SpoVG LRR_1 PF00560.33 RUS86868.1 - 0.19 12.4 17.1 4.9 8.1 0.5 6.9 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 RUS86868.1 - 0.4 10.9 11.2 21 5.5 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_5 PF13306.6 RUS86868.1 - 1.6 8.7 4.4 2.9 7.9 1.4 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Sec63 PF02889.16 RUS86869.1 - 6.7e-41 140.1 0.2 1.3e-40 139.2 0.2 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 RUS86869.1 - 6.2e-24 84.7 0.0 1.4e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RUS86869.1 - 2.5e-10 40.6 0.0 6.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS86869.1 - 0.00023 21.5 0.0 0.001 19.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RUS86869.1 - 0.054 13.8 0.3 0.32 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 RUS86869.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PTP2 PF17022.5 RUS86870.1 - 0.048 13.3 5.4 0.11 12.1 5.4 1.5 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia Ribosomal_S4 PF00163.19 RUS86870.1 - 0.069 14.1 2.1 0.15 13.0 0.9 2.2 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain FliD_N PF02465.18 RUS86870.1 - 1.9 9.2 15.9 0.13 13.0 7.1 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1835 PF08874.10 RUS86870.1 - 6.2 7.1 8.8 3.2 8.0 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Methyltransf_21 PF05050.12 RUS86871.1 - 0.0025 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain RRM_3 PF08777.11 RUS86871.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF4744 PF15918.5 RUS86873.1 - 6.6 7.7 34.5 9.2 7.2 8.3 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4744) ubiquitin PF00240.23 RUS86874.1 - 2.1e-15 56.2 0.1 2.9e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS86874.1 - 8.1e-07 28.8 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS86874.1 - 0.0011 19.4 0.1 0.0031 17.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RUS86874.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.6 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 RUS86874.1 - 0.065 13.6 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Hamartin PF04388.12 RUS86874.1 - 0.15 10.7 2.8 0.18 10.4 2.8 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4736 PF15883.5 RUS86875.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DUF725 PF05267.12 RUS86875.1 - 2.2 8.3 12.1 2.5 8.1 6.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF725) Ribosomal_L29 PF00831.23 RUS86876.1 - 2.8e-19 68.8 2.6 2.8e-19 68.8 2.6 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 RUS86876.1 - 0.0076 16.6 2.0 0.0076 16.6 2.0 1.6 1 1 1 2 2 2 1 Snapin/Pallidin zf-MYND PF01753.18 RUS86878.1 - 4.4e-06 26.7 11.9 4.4e-06 26.7 11.9 2.0 1 1 1 2 2 2 1 MYND finger zf-C6H2 PF15801.5 RUS86878.1 - 0.01 16.2 7.2 0.026 14.8 7.2 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding EGF_CA PF07645.15 RUS86878.1 - 0.096 12.9 3.4 0.22 11.7 3.4 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain Ecl1 PF12855.7 RUS86878.1 - 5.9 8.0 6.6 4.8 8.3 4.8 1.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins COX7a PF02238.15 RUS86879.1 - 2.7 8.5 6.5 0.79 10.2 1.4 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase subunit VII ubiquitin PF00240.23 RUS86880.1 - 9.3e-09 34.9 0.4 2.5e-08 33.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RUS86880.1 - 1.9e-05 25.0 0.1 0.00012 22.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RUS86880.1 - 0.01 15.7 0.2 0.034 14.0 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 RUS86880.1 - 0.08 13.0 0.2 0.51 10.4 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Pkinase PF00069.25 RUS86881.1 - 6e-64 216.0 0.4 8.2e-64 215.5 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86881.1 - 1.4e-48 165.5 0.0 2e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS86881.1 - 1.1e-06 28.2 0.1 1.1e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS86881.1 - 7.6e-06 25.1 1.0 7.6e-06 25.1 1.0 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS86881.1 - 0.00047 19.0 0.0 0.00047 19.0 0.0 1.6 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 RUS86881.1 - 0.0038 16.6 0.2 0.009 15.4 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS86881.1 - 0.12 12.2 0.2 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hid1 PF12722.7 RUS86882.1 - 6.2 4.8 6.6 7.9 4.5 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec16_C PF12931.7 RUS86886.1 - 1.7e-46 159.3 0.3 3.7e-46 158.2 0.3 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 RUS86886.1 - 1.2e-09 38.8 0.0 1.2e-09 38.8 0.0 3.2 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region Filament PF00038.21 RUS86887.1 - 8.4e-42 143.8 38.8 1.9e-38 132.8 38.8 2.1 1 1 0 1 1 1 1 Intermediate filament protein TMF_TATA_bd PF12325.8 RUS86887.1 - 1.5e-05 25.2 30.4 0.048 13.9 6.6 4.7 2 2 3 5 5 5 4 TATA element modulatory factor 1 TATA binding FPP PF05911.11 RUS86887.1 - 1.5e-05 23.4 26.9 4.5e-05 21.9 10.4 2.2 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 RUS86887.1 - 7.2e-05 21.8 34.1 0.00068 18.6 6.8 3.2 2 1 1 3 3 3 2 Spc7 kinetochore protein ERM PF00769.19 RUS86887.1 - 0.00052 19.9 31.9 0.034 14.0 5.2 3.2 2 1 1 3 3 3 2 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 RUS86887.1 - 0.00053 20.5 28.0 0.00067 20.2 1.3 5.4 2 1 2 5 5 5 2 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 RUS86887.1 - 0.00061 19.9 36.4 0.16 12.0 12.7 4.2 2 2 1 3 3 3 3 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 RUS86887.1 - 0.00062 19.0 31.4 0.0027 16.9 8.0 2.5 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region FlaC_arch PF05377.11 RUS86887.1 - 0.001 19.4 15.6 0.58 10.6 0.2 6.3 5 2 1 6 6 5 1 Flagella accessory protein C (FlaC) HAP1_N PF04849.13 RUS86887.1 - 0.0015 17.8 16.0 0.0015 17.8 16.0 2.7 2 1 1 3 3 3 1 HAP1 N-terminal conserved region KASH_CCD PF14662.6 RUS86887.1 - 0.0024 17.7 30.9 0.0048 16.7 8.7 3.6 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH LemA PF04011.12 RUS86887.1 - 0.0075 16.1 1.7 0.0075 16.1 1.7 3.2 2 1 1 3 3 3 1 LemA family APG6_N PF17675.1 RUS86887.1 - 0.0086 16.6 46.8 1.4 9.4 18.7 5.3 1 1 2 3 3 3 1 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 RUS86887.1 - 0.0093 16.0 7.0 0.054 13.5 0.5 3.4 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 RUS86887.1 - 0.014 15.7 36.2 0.11 12.7 14.3 3.0 2 2 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF148 PF02520.17 RUS86887.1 - 0.03 14.4 1.5 0.03 14.4 1.5 3.5 3 1 0 3 3 3 0 Domain of unknown function DUF148 BLOC1_2 PF10046.9 RUS86887.1 - 0.033 14.5 21.4 0.52 10.6 0.5 4.9 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 RUS86887.1 - 0.036 13.4 28.0 0.12 11.7 1.1 3.8 2 2 0 3 3 3 0 Protein of unknown function (DUF3450) HrpB7 PF09486.10 RUS86887.1 - 0.049 14.0 27.1 0.035 14.5 5.9 3.8 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Phage_GP20 PF06810.11 RUS86887.1 - 0.083 12.7 27.4 0.1 12.4 3.2 4.5 2 2 3 5 5 5 0 Phage minor structural protein GP20 Fez1 PF06818.15 RUS86887.1 - 0.089 13.2 35.1 1.1 9.7 5.4 3.3 1 1 1 3 3 3 0 Fez1 DivIC PF04977.15 RUS86887.1 - 0.1 12.4 26.4 0.43 10.4 3.1 5.5 4 2 0 5 5 5 0 Septum formation initiator TACC_C PF05010.14 RUS86887.1 - 0.11 12.2 23.8 0.78 9.5 13.0 2.8 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Atg14 PF10186.9 RUS86887.1 - 0.12 11.4 23.5 0.63 9.1 5.7 3.1 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 RUS86887.1 - 0.13 12.4 0.1 0.13 12.4 0.1 4.7 3 2 3 6 6 4 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 RUS86887.1 - 0.14 12.2 29.0 0.68 10.0 1.7 4.0 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 RUS86887.1 - 0.2 10.8 23.0 0.045 12.9 9.4 2.3 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF1465 PF07323.12 RUS86887.1 - 0.21 11.4 16.7 0.64 9.8 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) YabA PF06156.13 RUS86887.1 - 0.24 12.1 28.4 0.94 10.2 2.0 4.6 2 2 1 4 4 4 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 RUS86887.1 - 0.26 10.8 31.3 0.15 11.6 9.0 3.2 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.6 RUS86887.1 - 0.3 9.7 25.8 0.014 14.1 7.4 2.9 1 1 0 2 2 2 0 AAA domain DUF4201 PF13870.6 RUS86887.1 - 0.3 10.8 33.2 0.58 9.9 3.3 4.6 2 2 3 5 5 5 0 Domain of unknown function (DUF4201) Lebercilin PF15619.6 RUS86887.1 - 0.31 10.7 31.6 0.073 12.7 2.7 3.7 2 2 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.12 RUS86887.1 - 0.34 9.0 34.9 0.02 13.1 13.9 2.3 1 1 1 2 2 2 0 HOOK protein bZIP_1 PF00170.21 RUS86887.1 - 0.35 11.0 31.8 0.48 10.6 0.3 6.0 5 2 2 7 7 5 0 bZIP transcription factor SHE3 PF17078.5 RUS86887.1 - 0.36 10.5 30.4 0.46 10.1 16.9 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Lectin_N PF03954.14 RUS86887.1 - 0.38 10.5 13.6 6.5 6.5 3.4 4.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.11 RUS86887.1 - 0.38 10.6 13.3 1.5 8.6 0.5 3.3 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Tropomyosin PF00261.20 RUS86887.1 - 0.39 10.0 31.0 0.044 13.2 1.3 3.7 2 2 0 3 3 3 0 Tropomyosin DUF2730 PF10805.8 RUS86887.1 - 0.42 10.7 13.3 1.8 8.7 0.2 4.0 2 2 0 3 3 3 0 Protein of unknown function (DUF2730) USP8_interact PF08941.10 RUS86887.1 - 0.42 10.4 9.6 0.71 9.7 0.2 3.2 3 0 0 3 3 3 0 USP8 interacting Tup_N PF08581.10 RUS86887.1 - 0.44 10.9 28.9 0.29 11.4 2.3 5.4 4 2 0 4 4 4 0 Tup N-terminal GAS PF13851.6 RUS86887.1 - 0.45 9.8 40.0 1.6 8.1 6.7 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 RUS86887.1 - 0.46 10.4 27.2 1.4 8.8 3.4 4.0 2 2 0 3 3 3 0 Axonemal dynein light chain UPF0242 PF06785.11 RUS86887.1 - 0.47 10.5 37.0 0.33 11.0 7.5 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 RUS86887.1 - 0.48 10.9 23.0 4.8 7.7 1.8 4.5 2 2 1 3 3 3 0 Protein of unknown function DUF16 HMMR_N PF15905.5 RUS86887.1 - 0.49 9.8 33.6 0.37 10.2 4.5 3.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Prefoldin_3 PF13758.6 RUS86887.1 - 0.54 10.3 8.1 4.1 7.5 0.4 3.3 2 1 1 3 3 3 0 Prefoldin subunit FliD_C PF07195.12 RUS86887.1 - 0.6 9.5 9.0 4.4 6.7 0.7 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Rootletin PF15035.6 RUS86887.1 - 0.65 10.0 26.4 4.8 7.2 3.5 3.5 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 RUS86887.1 - 1.1 8.5 28.7 7.1 5.9 13.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 RUS86887.1 - 1.2 9.1 17.1 2.6 8.1 0.5 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 RUS86887.1 - 1.5 8.2 34.6 0.47 9.9 9.3 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 ZapB PF06005.12 RUS86887.1 - 1.5 9.3 36.8 2.4 8.7 9.3 5.1 3 2 2 5 5 4 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 RUS86887.1 - 1.7 8.7 38.7 1.4 8.9 7.0 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 RUS86887.1 - 1.9 8.1 26.0 0.19 11.4 1.3 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Nas2_N PF18265.1 RUS86887.1 - 1.9 8.4 14.5 0.99 9.4 0.5 5.0 5 0 0 5 5 4 0 Nas2 N_terminal domain TMF_DNA_bd PF12329.8 RUS86887.1 - 2 8.4 33.3 0.48 10.4 6.8 5.1 3 3 3 6 6 6 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 RUS86887.1 - 2.3 7.5 19.5 0.13 11.6 2.9 2.5 2 1 0 2 2 2 0 FAM76 protein Seryl_tRNA_N PF02403.22 RUS86887.1 - 2.4 8.4 29.1 0.98 9.7 5.2 4.1 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 RUS86887.1 - 2.4 8.3 25.7 0.36 11.0 4.1 5.8 3 3 1 5 5 5 0 Basic region leucine zipper PRKG1_interact PF15898.5 RUS86887.1 - 2.8 8.9 34.2 1.5 9.7 6.9 5.2 3 1 2 5 5 3 0 cGMP-dependent protein kinase interacting domain DUF2203 PF09969.9 RUS86887.1 - 3.3 8.4 22.5 5.9 7.6 0.2 4.6 2 2 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 RUS86887.1 - 4 5.9 13.9 3.2 6.2 3.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Gp-FAR-1 PF05823.12 RUS86887.1 - 4.1 7.7 13.4 3.1 8.2 0.4 3.8 2 2 2 4 4 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4200 PF13863.6 RUS86887.1 - 4.3 7.8 33.0 0.059 13.8 5.0 4.6 2 2 1 3 3 2 0 Domain of unknown function (DUF4200) CALCOCO1 PF07888.11 RUS86887.1 - 4.3 6.1 34.9 7 5.4 34.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-H PF05837.12 RUS86887.1 - 4.4 7.7 28.5 0.81 10.1 6.2 4.1 2 1 2 4 4 4 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 RUS86887.1 - 4.7 7.4 17.4 7.7 6.7 1.6 3.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family WD40_alt PF14077.6 RUS86887.1 - 5.7 6.9 7.8 31 4.5 0.5 4.2 4 0 0 4 4 3 0 Alternative WD40 repeat motif TMPIT PF07851.13 RUS86887.1 - 7.2 5.8 18.3 0.7 9.1 0.6 3.3 2 1 1 3 3 3 0 TMPIT-like protein DUF724 PF05266.14 RUS86887.1 - 8.4 6.2 23.3 1.4 8.7 3.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Swi5 PF07061.11 RUS86887.1 - 8.4 6.6 19.0 3.5 7.8 1.9 5.0 2 2 2 4 4 4 0 Swi5 MbeD_MobD PF04899.12 RUS86887.1 - 8.6 6.6 13.8 11 6.2 1.3 4.7 4 0 0 4 4 4 0 MbeD/MobD like DAO PF01266.24 RUS86889.1 - 9.6e-45 153.7 0.1 8e-43 147.4 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS86889.1 - 2.5e-06 26.9 0.1 0.0032 16.8 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS86889.1 - 1.5e-05 25.1 0.0 3.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 RUS86889.1 - 3.8e-05 23.1 0.0 0.0089 15.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS86889.1 - 4.4e-05 22.7 0.0 0.0007 18.8 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 RUS86889.1 - 7.8e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS86889.1 - 0.0001 21.5 0.2 0.00025 20.3 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RUS86889.1 - 0.00054 18.8 0.0 0.023 13.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 RUS86889.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 RUS86889.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 RUS86889.1 - 0.0097 15.2 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 RUS86889.1 - 0.032 14.8 0.0 0.72 10.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrmO_C PF18389.1 RUS86890.1 - 0.038 14.1 0.1 0.45 10.7 0.0 2.7 2 0 0 2 2 2 0 TrmO C-terminal domain DUF445 PF04286.12 RUS86890.1 - 1.5 8.6 18.9 0.27 11.0 8.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Cortex-I_coil PF09304.10 RUS86890.1 - 2.3 8.5 15.3 1.7 8.9 0.7 3.6 3 1 1 4 4 4 0 Cortexillin I, coiled coil Fibrinogen_C PF00147.18 RUS86891.1 - 3.2e-48 164.5 0.3 2.6e-43 148.4 0.2 2.3 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain PH PF00169.29 RUS86892.1 - 2.7e-12 47.1 0.0 1e-11 45.3 0.0 1.9 2 0 0 2 2 2 1 PH domain Herpes_capsid PF06112.11 RUS86892.1 - 7.2 6.6 15.0 0.19 11.8 7.6 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein 7tm_1 PF00001.21 RUS86893.1 - 2.6e-30 105.7 19.5 3.2e-30 105.3 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS86893.1 - 0.00066 19.4 17.6 0.00066 19.4 17.6 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS86894.1 - 1.5e-07 31.1 6.8 2e-07 30.6 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SAPS PF04499.15 RUS86894.1 - 0.0064 15.3 4.4 0.0072 15.2 4.4 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 RUS86894.1 - 0.016 15.0 2.6 0.022 14.6 2.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 RUS86894.1 - 0.075 12.0 1.5 0.1 11.6 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Methyltr_RsmB-F PF01189.17 RUS86895.1 - 3.9e-38 131.1 0.0 2.5e-37 128.5 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2052 PF09747.9 RUS86895.1 - 3.7 7.6 12.5 4.8 7.2 4.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ThiF PF00899.21 RUS86896.1 - 3e-22 79.2 0.0 5.2e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 ThiF family Glycos_trans_3N PF02885.17 RUS86896.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 RUS86898.1 - 7.8e-48 163.1 0.3 1.3e-47 162.4 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86898.1 - 1.6e-21 76.8 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 RUS86898.1 - 0.006 15.6 0.1 0.0092 15.0 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Inositol_P PF00459.25 RUS86899.1 - 2.3e-71 240.5 0.4 2.7e-71 240.3 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Hormone_recep PF00104.30 RUS86900.1 - 3.4e-36 124.8 0.0 7.6e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS86900.1 - 4.2e-29 100.8 19.3 8.5e-29 99.8 19.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Afi1 PF07792.12 RUS86901.1 - 0.19 12.2 9.0 0.27 11.7 9.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 RUS86901.1 - 1.5 7.0 24.6 1.8 6.6 24.6 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 RUS86901.1 - 1.5 8.6 17.0 2.5 7.9 17.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 RUS86901.1 - 2.5 7.4 16.0 3 7.1 16.0 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 RUS86901.1 - 2.7 7.9 24.7 2.7 7.9 24.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RUS86901.1 - 5.3 5.0 38.2 7.4 4.5 38.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS86901.1 - 8.3 4.6 20.7 11 4.2 20.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hormone_recep PF00104.30 RUS86903.1 - 4.7e-11 42.7 0.2 6.5e-11 42.2 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EGF_2 PF07974.13 RUS86904.1 - 8.4e-15 54.8 48.8 1.8e-05 25.0 14.8 3.1 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.27 RUS86904.1 - 5e-11 42.7 38.3 0.00038 20.7 8.0 3.9 3 2 0 3 3 3 3 EGF-like domain hEGF PF12661.7 RUS86904.1 - 9.5e-08 32.4 47.1 0.0012 19.4 8.8 5.2 5 1 1 6 6 6 3 Human growth factor-like EGF Laminin_EGF PF00053.24 RUS86904.1 - 0.0086 16.2 39.5 2.3 8.4 9.4 3.3 1 1 2 3 3 3 3 Laminin EGF domain cEGF PF12662.7 RUS86904.1 - 0.35 10.8 27.3 0.52 10.3 4.9 4.1 3 1 0 3 3 3 0 Complement Clr-like EGF-like EB PF01683.18 RUS86904.1 - 5.2 7.4 36.8 7 7.0 9.3 3.8 1 1 2 3 3 3 0 EB module VWD PF00094.25 RUS86905.1 - 1.5e-12 48.0 0.0 2.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain EGF_Tenascin PF18720.1 RUS86905.1 - 6 7.0 15.8 0.97 9.6 10.4 2.7 3 0 0 3 3 3 0 Tenascin EGF domain Laminin_EGF PF00053.24 RUS86905.1 - 9.7 6.4 14.5 83 3.4 0.1 3.3 2 0 0 2 2 2 0 Laminin EGF domain T4_deiodinase PF00837.17 RUS86906.1 - 1.1e-21 77.2 0.0 7.8e-21 74.5 0.0 1.9 1 1 0 1 1 1 1 Iodothyronine deiodinase Trypsin PF00089.26 RUS86907.1 - 1.7e-34 119.6 0.0 1.8e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF4106 PF13388.6 RUS86908.1 - 0.002 17.4 22.0 0.0024 17.2 22.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF3824 PF12868.7 RUS86908.1 - 7.1 7.3 22.8 8 7.1 22.8 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytochrom_B558a PF05038.13 RUS86909.1 - 2.9e-48 163.9 0.7 3.3e-48 163.7 0.7 1.0 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 RUS86909.1 - 7.4e-06 26.3 4.5 0.0013 19.0 1.2 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 RUS86909.1 - 0.0066 16.5 7.8 0.044 13.8 7.8 1.9 1 1 0 1 1 1 1 COPI associated protein Peptidase_M41 PF01434.18 RUS86910.1 - 1.3e-69 233.9 0.4 2.1e-69 233.2 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RUS86910.1 - 5.2e-43 146.6 0.0 1.2e-42 145.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS86910.1 - 2.2e-14 53.0 0.1 5.6e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 RUS86910.1 - 8.6e-05 22.9 0.3 0.00037 20.8 0.3 2.1 1 1 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 RUS86910.1 - 0.00028 20.9 0.2 0.0045 17.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS86910.1 - 0.00045 20.5 0.0 0.12 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RUS86910.1 - 0.0011 18.8 0.0 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS86910.1 - 0.0019 18.3 0.0 0.0094 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RUS86910.1 - 0.0024 18.3 0.1 0.24 11.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 RUS86910.1 - 0.0061 15.8 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 RUS86910.1 - 0.015 15.5 0.6 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RUS86910.1 - 0.05 13.0 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RUS86910.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec7 PF01369.20 RUS86910.1 - 0.061 13.0 0.6 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Sec7 domain DUF1414 PF07208.11 RUS86910.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) AAA_33 PF13671.6 RUS86910.1 - 0.097 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1283 PF06932.11 RUS86911.1 - 0.63 10.3 5.7 10 6.4 5.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1283) AAA_22 PF13401.6 RUS86912.1 - 0.03 14.6 0.0 0.094 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS86912.1 - 0.1 13.0 0.0 0.42 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain PQQ PF01011.21 RUS86913.1 - 0.035 14.1 0.0 22 5.2 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 RUS86913.1 - 0.12 12.7 0.3 43 4.5 0.0 4.0 2 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.21 RUS86914.1 - 1.1e-08 35.3 13.6 1.1e-08 35.3 13.6 1.7 2 0 0 2 2 2 1 ATP synthase subunit C Presenilin PF01080.17 RUS86915.1 - 0.093 11.5 9.2 0.098 11.4 9.2 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 RUS86915.1 - 0.11 11.6 4.7 0.12 11.6 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 RUS86915.1 - 0.2 11.8 4.2 0.23 11.6 4.2 1.2 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.11 RUS86915.1 - 0.22 11.6 17.2 0.28 11.2 17.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SLC12 PF03522.15 RUS86915.1 - 0.52 9.3 11.7 0.61 9.0 11.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF3486 PF11985.8 RUS86915.1 - 0.76 10.2 16.5 1.1 9.7 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) DUF4569 PF15133.6 RUS86915.1 - 0.98 9.1 9.2 1.2 8.7 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NPR3 PF03666.13 RUS86915.1 - 1.2 7.9 14.8 1.4 7.7 14.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3340 PF11818.8 RUS86915.1 - 1.8 8.7 22.4 3.1 7.9 22.4 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Hid1 PF12722.7 RUS86915.1 - 2.5 6.1 10.6 2.9 5.9 10.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 RUS86915.1 - 2.7 7.4 20.5 3.6 7.0 20.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MAJIN PF15077.6 RUS86915.1 - 3.5 7.3 14.6 4.6 7.0 14.6 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4551 PF15087.6 RUS86915.1 - 4.8 5.9 9.8 5.2 5.8 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Membralin PF09746.9 RUS86915.1 - 7.6 5.5 6.1 8.4 5.3 6.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3807 PF12720.7 RUS86915.1 - 7.8 6.7 22.6 10 6.3 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 RUS86915.1 - 8.9 6.0 22.2 11 5.7 22.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 RUS86915.1 - 9.3 6.2 9.4 11 6.0 9.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EGF_CA PF07645.15 RUS86916.1 - 5.3e-08 32.9 9.2 5.3e-08 32.9 9.2 3.4 3 1 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 RUS86916.1 - 3.7e-05 23.8 6.4 3.7e-05 23.8 6.4 3.4 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 RUS86916.1 - 0.00015 22.2 2.4 0.00015 22.2 2.4 4.0 4 0 0 4 4 4 1 Human growth factor-like EGF EGF PF00008.27 RUS86916.1 - 0.0094 16.2 2.9 0.0094 16.2 2.9 3.6 3 1 1 4 4 4 1 EGF-like domain FXa_inhibition PF14670.6 RUS86916.1 - 0.033 14.5 5.3 0.033 14.5 5.3 3.2 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site EB PF01683.18 RUS86917.1 - 9e-27 93.1 140.2 0.00019 21.7 8.1 11.1 2 2 9 11 11 11 10 EB module cEGF PF12662.7 RUS86917.1 - 5.1 7.1 52.1 1.8 8.6 0.6 9.1 8 0 0 8 8 8 0 Complement Clr-like EGF-like bZIP_1 PF00170.21 RUS86918.1 - 7.2e-06 26.0 9.0 7.2e-06 26.0 9.0 1.8 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS86918.1 - 0.00014 21.9 10.1 0.00014 21.9 10.1 1.9 3 0 0 3 3 1 1 Basic region leucine zipper HAP1_N PF04849.13 RUS86918.1 - 0.0099 15.1 1.4 0.015 14.5 1.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FlaC_arch PF05377.11 RUS86918.1 - 0.022 15.1 1.4 0.051 14.0 1.4 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) NRBF2 PF08961.10 RUS86918.1 - 0.029 14.0 1.8 0.061 12.9 1.8 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DivIVA PF05103.13 RUS86918.1 - 0.041 14.0 3.4 0.12 12.4 3.4 1.8 1 1 0 1 1 1 0 DivIVA protein Cnn_1N PF07989.11 RUS86918.1 - 0.098 12.8 6.3 0.06 13.5 3.6 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CASP_C PF08172.12 RUS86918.1 - 0.11 11.9 2.6 0.14 11.5 1.9 1.4 1 1 0 1 1 1 0 CASP C terminal APG6_N PF17675.1 RUS86918.1 - 0.11 13.0 2.7 0.21 12.1 2.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 RUS86918.1 - 0.28 11.4 1.6 0.76 10.0 1.6 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 RUS86918.1 - 0.61 10.3 6.5 0.24 11.6 3.8 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APC_N_CC PF16689.5 RUS86918.1 - 0.73 9.9 3.6 1.5 8.9 3.6 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain PRP1_N PF06424.12 RUS86918.1 - 1.9 8.9 6.3 3.7 7.9 2.5 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DivIC PF04977.15 RUS86918.1 - 2.1 8.2 6.6 0.31 10.9 2.6 1.7 2 0 0 2 2 2 0 Septum formation initiator Dynein_IC2 PF11540.8 RUS86919.1 - 1.8e-14 53.4 1.0 1.8e-14 53.4 1.0 1.7 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 RUS86919.1 - 7.1e-06 26.7 12.4 0.22 12.5 0.1 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS86919.1 - 0.0024 18.1 0.1 1.4 9.2 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Fis1_TPR_C PF14853.6 RUS86920.1 - 0.00044 20.3 0.2 0.00073 19.6 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat DUF2457 PF10446.9 RUS86920.1 - 0.0034 16.6 34.0 0.0034 16.6 34.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RUS86920.1 - 0.0055 14.9 61.2 0.0095 14.1 39.8 2.1 2 0 0 2 2 2 2 DNA polymerase phi DUF2076 PF09849.9 RUS86920.1 - 1.1 9.3 36.3 0.15 12.0 16.6 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Afi1 PF07792.12 RUS86920.1 - 1.9 8.9 31.6 0.095 13.2 5.5 3.0 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking XLF PF09302.11 RUS86921.1 - 7e-30 104.5 0.0 9.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4342 PF14242.6 RUS86921.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) LRR_5 PF13306.6 RUS86921.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) cwf18 PF08315.12 RUS86922.1 - 1.6e-35 122.7 13.0 1.9e-35 122.5 13.0 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 RUS86922.1 - 0.085 12.9 2.7 0.18 11.8 2.7 1.5 1 1 0 1 1 1 0 Sir4 SID domain BET PF17035.5 RUS86922.1 - 0.19 11.9 5.6 2.4 8.4 0.5 2.4 1 1 1 2 2 2 0 Bromodomain extra-terminal - transcription regulation Spore_III_AB PF09548.10 RUS86922.1 - 0.23 11.5 1.2 0.35 11.0 0.2 1.7 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Kunitz_BPTI PF00014.23 RUS86923.1 - 3.3e-17 62.5 6.5 9e-17 61.1 6.5 1.8 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain CTNNB1_binding PF08347.11 RUS86923.1 - 0.88 9.7 3.9 0.31 11.2 1.0 1.8 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Utp14 PF04615.13 RUS86924.1 - 0.014 14.1 18.8 0.018 13.6 18.8 1.1 1 0 0 1 1 1 0 Utp14 protein PT PF04886.12 RUS86924.1 - 0.019 14.5 0.1 0.053 13.1 0.1 1.7 1 0 0 1 1 1 0 PT repeat Fer2_2 PF01799.20 RUS86925.1 - 3.5e-30 103.9 0.1 3.5e-30 103.9 0.1 2.2 3 0 0 3 3 3 1 [2Fe-2S] binding domain Fer2 PF00111.27 RUS86925.1 - 1.3e-06 28.2 1.0 1.3e-06 28.2 1.0 2.5 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 RUS86926.1 - 5.6e-128 427.8 0.0 8.1e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 RUS86926.1 - 4.2e-26 91.5 0.0 9e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 RUS86926.1 - 4.3e-21 75.0 0.0 1.1e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain AA_permease_2 PF13520.6 RUS86927.1 - 2.1e-36 125.7 26.9 2.1e-36 125.7 26.9 2.3 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 RUS86927.1 - 2.7e-27 95.5 26.4 2.7e-27 95.5 26.4 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RUS86927.1 - 7.2e-16 58.0 9.1 7.2e-16 58.0 9.1 3.0 2 0 0 2 2 2 1 C-terminus of AA_permease Period_C PF12114.8 RUS86928.1 - 1.4e-15 57.4 3.4 3.4e-09 36.6 3.5 6.7 7 0 0 7 7 7 2 Period protein 2/3C-terminal region PAS_11 PF14598.6 RUS86928.1 - 1.2e-13 51.2 0.0 1.2e-11 44.7 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 RUS86928.1 - 9.7e-08 32.0 0.0 6.4e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 RUS86928.1 - 1.3e-06 28.6 0.0 4.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 RUS86928.1 - 0.039 14.2 0.0 13 6.1 0.0 3.4 3 0 0 3 3 3 0 PAS domain Chalcone_2 PF16035.5 RUS86928.1 - 7.3 6.3 7.3 0.3 10.8 0.5 2.1 3 0 0 3 3 3 0 Chalcone isomerase like FeoB_Cyto PF17910.1 RUS86929.1 - 2.1e-05 25.0 16.6 1.5e+04 -3.4 16.6 5.3 1 1 0 1 1 1 0 FeoB cytosolic helical domain Spin-Ssty PF02513.17 RUS86929.1 - 0.0001 22.0 23.7 37 4.2 0.2 10.2 1 1 6 9 9 9 0 Spin/Ssty Family DUF3801 PF12687.7 RUS86929.1 - 0.00059 19.9 43.4 4.9 7.2 3.9 6.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3801) MerR_1 PF13411.6 RUS86929.1 - 0.41 10.8 26.8 96 3.2 0.3 9.1 1 1 11 14 14 14 0 MerR HTH family regulatory protein RasGEF_N_2 PF14663.6 RUS86929.1 - 2 8.8 17.9 44 4.5 0.6 5.3 1 1 8 9 9 9 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HBM PF16591.5 RUS86929.1 - 2.4 7.5 35.3 7 6.0 2.5 4.7 1 1 4 5 5 5 0 Helical bimodular sensor domain Adeno_E4_34 PF04528.13 RUS86930.1 - 0.64 9.9 40.8 3.9 7.3 2.6 6.8 1 1 7 8 8 8 0 Adenovirus early E4 34 kDa protein conserved region Pkinase_Tyr PF07714.17 RUS86931.1 - 2.8e-85 285.7 0.0 4.2e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS86931.1 - 2.6e-40 138.5 0.0 4.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.6 RUS86931.1 - 3.7e-06 26.6 0.4 0.007 16.2 0.2 2.5 2 0 0 2 2 2 2 UBA-like domain Kinase-like PF14531.6 RUS86931.1 - 0.0047 16.3 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GTPase_binding PF09027.10 RUS86931.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 GTPase binding SH3_2 PF07653.17 RUS86931.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain APH PF01636.23 RUS86931.1 - 0.15 11.9 0.0 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Reeler PF02014.16 RUS86933.1 - 6.2e-22 78.7 0.4 1e-21 78.0 0.4 1.4 1 0 0 1 1 1 1 Reeler domain zf-H2C2_2 PF13465.6 RUS86934.1 - 4.3e-64 210.3 79.2 1.7e-07 31.3 2.7 12.5 13 0 0 13 13 13 10 Zinc-finger double domain zf-C2H2 PF00096.26 RUS86934.1 - 2.7e-47 156.6 81.0 4.1e-05 23.8 0.9 13.4 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS86934.1 - 3e-33 111.6 84.8 0.0003 21.4 1.3 13.8 13 0 0 13 13 12 11 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS86934.1 - 2.7e-11 43.4 37.0 0.3 11.4 0.2 11.6 12 0 0 12 12 12 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS86934.1 - 1.6e-09 37.8 54.8 0.057 13.8 0.5 11.7 11 0 0 11 11 11 4 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RUS86934.1 - 0.00019 20.9 39.0 3.2 7.4 0.1 11.0 12 0 0 12 12 12 3 Ubiquitin-Binding Zinc Finger BolA PF01722.18 RUS86934.1 - 0.0023 18.2 14.2 5.2 7.4 0.0 6.4 3 2 3 6 6 6 1 BolA-like protein zf-C2H2_3rep PF18868.1 RUS86934.1 - 0.0087 16.7 35.7 2.9 8.6 1.8 8.3 4 3 2 6 6 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 RUS86934.1 - 0.016 15.2 0.4 0.016 15.2 0.4 12.0 12 0 0 12 12 12 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 RUS86934.1 - 0.016 15.3 41.1 1.4 9.1 0.7 7.8 3 2 5 9 9 9 0 Zinc ribbon domain DUF2256 PF10013.9 RUS86934.1 - 0.046 13.8 0.5 0.046 13.8 0.5 8.7 10 0 0 10 10 10 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_5 PF13909.6 RUS86934.1 - 0.29 10.9 56.5 0.71 9.7 0.7 10.9 10 0 0 10 10 10 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS86934.1 - 0.77 9.6 71.5 0.038 13.7 2.7 10.9 12 0 0 12 12 11 0 zinc-finger C2H2-type DUF3268 PF11672.8 RUS86934.1 - 2.3 8.6 33.5 0.18 12.2 0.2 6.4 5 1 1 6 6 6 0 zinc-finger-containing domain zf-trcl PF13451.6 RUS86934.1 - 2.8 7.9 39.3 1.3 9.0 2.7 9.7 9 2 0 9 9 9 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 RUS86934.1 - 8.2 7.3 55.1 2.2 9.1 1.3 7.9 5 2 4 9 9 8 0 zinc-ribbon family DDE_Tnp_1_7 PF13843.6 RUS86935.1 - 0.037 13.3 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Transposase IS4 DUF4573 PF15140.6 RUS86936.1 - 9.9e-36 123.2 11.7 6e-13 49.0 2.0 3.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) TPP_enzyme_N PF02776.18 RUS86936.1 - 4e-06 26.6 59.6 0.23 11.1 4.8 8.3 1 1 12 13 13 13 13 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain OTU PF02338.19 RUS86937.1 - 8.1e-06 26.3 0.2 2.4e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease PHD PF00628.29 RUS86937.1 - 3.1e-05 23.8 8.6 3.1e-05 23.8 8.6 2.4 2 0 0 2 2 2 1 PHD-finger Peptidase_C65 PF10275.9 RUS86937.1 - 0.00024 20.6 2.2 0.00077 19.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase C65 Otubain PHD_2 PF13831.6 RUS86937.1 - 0.0024 17.4 2.9 0.0024 17.4 2.9 3.3 4 0 0 4 4 4 1 PHD-finger C1_1 PF00130.22 RUS86937.1 - 0.0066 16.3 2.9 0.0066 16.3 2.9 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MDM31_MDM32 PF08118.11 RUS86937.1 - 0.1 11.2 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins C1_2 PF03107.16 RUS86937.1 - 0.16 12.3 6.1 0.075 13.4 1.3 2.7 2 0 0 2 2 2 0 C1 domain FAM194 PF14977.6 RUS86938.1 - 4.5e-06 26.1 0.0 6.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 FAM194 protein Phosphodiest PF01663.22 RUS86939.1 - 8.3e-10 38.8 0.8 4e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 RUS86939.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Ctr PF04145.15 RUS86939.1 - 0.2 12.3 3.9 1.1 9.8 0.3 3.6 4 1 0 4 4 4 0 Ctr copper transporter family XK-related PF09815.9 RUS86940.1 - 8.4e-14 51.4 32.7 1.8e-13 50.3 32.7 1.5 1 1 0 1 1 1 1 XK-related protein DUF4139 PF13598.6 RUS86940.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Astacin PF01400.24 RUS86941.1 - 9e-65 217.9 1.0 1.3e-64 217.4 1.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 RUS86941.1 - 1.5e-09 38.2 20.7 4.1e-07 30.4 7.5 3.2 3 0 0 3 3 3 2 ShK domain-like Peptidase_M10 PF00413.24 RUS86941.1 - 8e-05 22.5 2.4 0.036 13.9 0.1 2.3 2 0 0 2 2 2 2 Matrixin Peptidase_M66 PF10462.9 RUS86941.1 - 0.0022 17.0 0.2 0.0035 16.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 RUS86941.1 - 0.0032 17.2 0.3 0.0056 16.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS86941.1 - 0.037 14.6 0.3 0.088 13.3 0.3 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 RUS86941.1 - 0.064 12.8 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 RUS86941.1 - 0.35 10.7 2.4 0.68 9.8 1.9 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Acetyltransf_10 PF13673.7 RUS86942.1 - 1.2e-07 31.7 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS86942.1 - 4e-06 27.1 0.3 1e-05 25.7 0.2 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family PARP PF00644.20 RUS86942.1 - 0.00023 20.8 0.1 0.00072 19.2 0.0 1.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Acetyltransf_7 PF13508.7 RUS86942.1 - 0.00095 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2122 PF09895.9 RUS86942.1 - 0.028 14.8 0.1 0.071 13.5 0.1 1.6 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) DUF4820 PF16091.5 RUS86942.1 - 0.75 9.1 6.3 1.4 8.3 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GDC-P PF02347.16 RUS86943.1 - 7.1e-187 621.5 0.0 6.7e-176 585.3 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 RUS86943.1 - 1.1e-06 28.2 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RUS86943.1 - 1.2e-05 24.4 0.0 9.5e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 RUS86943.1 - 0.032 12.9 0.4 0.36 9.5 0.1 2.1 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DPBB_1 PF03330.18 RUS86943.1 - 0.14 12.5 0.0 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 Lytic transglycolase Pkinase PF00069.25 RUS86945.1 - 7.9e-60 202.4 0.0 9.9e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS86945.1 - 4e-38 131.2 0.0 5.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS86945.1 - 2.9e-10 40.0 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RUS86945.1 - 0.00045 19.1 0.0 0.0018 17.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RUS86945.1 - 0.042 13.8 0.0 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TMEM234 PF10639.9 RUS86946.1 - 5.3e-41 139.3 4.1 6.1e-41 139.1 4.1 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 RUS86946.1 - 1.5e-06 28.4 7.8 0.00017 21.8 6.6 2.1 1 1 1 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 RUS86946.1 - 0.00097 18.3 0.1 0.0011 18.2 0.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Gaa1 PF04114.14 RUS86946.1 - 0.029 13.4 1.3 0.035 13.1 1.3 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Gram_pos_anchor PF00746.21 RUS86946.1 - 0.35 10.9 1.4 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Exo_endo_phos PF03372.23 RUS86947.1 - 9.5e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS86947.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase T4_tail_cap PF11091.8 RUS86947.1 - 0.021 13.8 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Tail-tube assembly protein Kelch_1 PF01344.25 RUS86948.1 - 9.1e-80 262.1 9.3 5e-15 54.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS86948.1 - 1.6e-42 142.4 2.1 2.3e-07 30.9 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 RUS86948.1 - 2.1e-31 106.7 2.6 4e-06 26.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 RUS86948.1 - 1.4e-27 95.8 0.7 2.6e-27 94.9 0.7 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 RUS86948.1 - 7.3e-24 84.1 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 RUS86948.1 - 1e-23 83.0 7.7 0.00049 20.3 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS86948.1 - 4.8e-15 55.3 0.1 0.17 11.9 0.0 6.2 3 1 3 6 6 6 4 Galactose oxidase, central domain DUF3342 PF11822.8 RUS86948.1 - 1.8e-06 28.0 0.0 0.0025 18.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 RUS86948.1 - 0.0003 20.7 8.7 2.3 8.3 0.1 5.0 5 0 0 5 5 5 2 Kelch motif DUF3522 PF12036.8 RUS86949.1 - 1.9e-09 38.1 2.1 3.6e-09 37.2 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) EGF_2 PF07974.13 RUS86949.1 - 0.073 13.4 8.0 0.18 12.2 8.0 1.7 1 0 0 1 1 1 0 EGF-like domain Peptidase_M4_C PF02868.15 RUS86950.1 - 3.9e-16 59.4 0.0 6.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 RUS86950.1 - 4.7e-14 53.1 0.2 8.7e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Vta1 PF04652.16 RUS86950.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Vta1 like Lipocalin PF00061.23 RUS86951.1 - 0.001 19.3 0.1 0.0012 19.0 0.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family FAF PF11250.8 RUS86951.1 - 0.012 15.8 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 Fantastic Four meristem regulator Lipocalin PF00061.23 RUS86952.1 - 6.9e-08 32.8 1.5 2.2e-07 31.1 0.9 1.7 1 1 1 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS86952.1 - 0.00019 21.4 0.1 0.00024 21.0 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family ENTH PF01417.20 RUS86952.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 ENTH domain MATH PF00917.26 RUS86953.1 - 0.00039 20.6 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 MATH domain DUF4763 PF15960.5 RUS86953.1 - 0.061 12.6 0.7 0.12 11.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) GalKase_gal_bdg PF10509.9 RUS86954.1 - 0.00019 20.9 0.0 69 3.1 0.0 5.2 1 1 5 6 6 6 0 Galactokinase galactose-binding signature APG6_N PF17675.1 RUS86954.1 - 0.0069 16.9 2.1 0.0096 16.5 2.1 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF1011 PF06237.12 RUS86954.1 - 0.11 12.9 2.3 0.14 12.5 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) DUF1381 PF07129.11 RUS86954.1 - 0.11 12.4 13.7 78 3.2 0.0 6.9 2 2 4 6 6 6 0 Protein of unknown function (DUF1381) T_Ag_DNA_bind PF02217.16 RUS86954.1 - 0.14 12.8 9.8 3.6 8.3 0.4 3.0 1 1 3 4 4 4 0 Origin of replication binding protein DUF3738 PF12543.8 RUS86954.1 - 0.27 11.4 3.1 13 5.9 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3738) DUF3285 PF11688.8 RUS86954.1 - 0.44 10.5 4.7 2.2e+02 1.8 0.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF3285) DUF2672 PF10878.8 RUS86954.1 - 2 8.4 10.5 44 4.1 0.1 5.5 1 1 5 6 6 6 0 Protein of unknown function (DUF2672) Atg8 PF02991.16 RUS86955.1 - 4.8e-25 87.8 0.0 5.3e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RUS86955.1 - 4.9e-05 23.7 0.0 5.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 RUS86956.1 - 2.1e-47 159.6 0.0 2.4e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RUS86956.1 - 1.6e-05 25.2 0.0 2.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF1700 PF08006.11 RUS86957.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PetL PF05115.14 RUS86957.1 - 1 9.4 8.5 5.7 7.0 8.5 2.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) PHBC_N PF12551.8 RUS86958.1 - 0.58 10.0 5.2 1.3 8.8 5.2 1.6 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal RPEL PF02755.15 RUS86959.1 - 1.2e-12 47.1 17.4 10 6.0 0.1 10.4 11 0 0 11 11 11 8 RPEL repeat Caerin_1 PF07440.12 RUS86959.1 - 0.0084 16.2 5.7 15 5.8 2.5 5.1 3 2 0 3 3 3 1 Caerin 1 protein Sigma_1_2 PF03084.14 RUS86959.1 - 0.12 11.7 0.6 6 6.0 0.1 2.3 1 1 1 2 2 2 0 Reoviral Sigma1/Sigma2 family Forkhead PF00250.18 RUS86960.1 - 2.5e-56 187.9 1.3 5e-39 132.5 0.1 2.3 2 0 0 2 2 2 2 Forkhead domain Sperm_Ag_HE2 PF05324.13 RUS86960.1 - 0.31 11.5 4.3 10 6.7 0.2 2.6 2 0 0 2 2 2 0 Sperm antigen HE2 ERbeta_N PF12497.8 RUS86961.1 - 0.047 13.5 0.4 0.047 13.5 0.4 1.9 2 0 0 2 2 2 0 Estrogen receptor beta Forkhead PF00250.18 RUS86963.1 - 1.8e-37 127.5 0.0 3.2e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Pex14_N PF04695.13 RUS86963.1 - 10 6.8 11.4 5.2 7.7 1.6 3.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GDP_Man_Dehyd PF16363.5 RUS86964.1 - 1.8e-158 527.2 0.1 2.1e-158 527.0 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RUS86964.1 - 3.7e-75 252.5 0.1 4.6e-75 252.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RUS86964.1 - 5e-08 32.4 0.0 7.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RUS86964.1 - 0.00033 19.9 0.0 0.00066 18.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 RUS86964.1 - 0.024 14.2 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Ank_2 PF12796.7 RUS86965.1 - 4.9e-08 33.4 1.3 0.0002 21.9 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS86965.1 - 1.4e-05 25.1 0.4 0.24 12.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 RUS86965.1 - 0.00094 19.4 0.1 0.012 16.0 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SAM_1 PF00536.30 RUS86966.1 - 1e-12 48.3 1.5 1.3e-06 28.7 0.0 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS86966.1 - 1.3e-10 41.2 0.6 0.00011 22.3 0.0 3.3 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) NCD1 PF04904.13 RUS86966.1 - 0.0047 16.9 0.3 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) HEAT PF02985.22 RUS86968.1 - 0.0033 17.5 2.3 0.061 13.6 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat Uso1_p115_head PF04869.14 RUS86968.1 - 0.083 12.0 0.6 6.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region PrmA PF06325.13 RUS86971.1 - 1.8e-08 34.2 0.2 3.4e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RUS86971.1 - 8.5e-07 29.6 0.0 0.00028 21.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 RUS86971.1 - 0.00037 20.1 0.1 0.00096 18.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 RUS86971.1 - 0.00071 19.4 0.0 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 RUS86971.1 - 0.00089 19.2 0.2 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 RUS86971.1 - 0.002 17.3 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 RUS86971.1 - 0.0073 16.9 0.0 0.059 14.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS86971.1 - 0.014 15.0 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 RUS86971.1 - 0.047 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RUS86971.1 - 0.054 14.2 0.0 0.38 11.5 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_16 PF10294.9 RUS86971.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_20 PF12147.8 RUS86971.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PEPCK_GTP PF00821.18 RUS86972.1 - 4.4e-158 525.8 0.0 6.5e-158 525.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 RUS86972.1 - 8e-87 290.4 0.0 1.1e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Adeno_E3_CR1 PF02440.15 RUS86972.1 - 0.16 11.8 0.2 0.67 9.8 0.1 2.1 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 Ribosomal_L14e PF01929.17 RUS86973.1 - 3e-29 101.3 7.7 3e-29 101.3 7.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L14 FAD_binding_4 PF01565.23 RUS86974.1 - 1.9e-19 69.8 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 RUS86974.1 - 0.035 12.8 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Integrin_b_cyt PF08725.11 RUS86975.1 - 2.2e-15 56.1 1.5 3.5e-15 55.4 1.5 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 RUS86975.1 - 1.3e-12 48.0 8.2 1.3e-12 48.0 8.2 3.3 3 1 1 4 4 4 1 Integrin beta tail domain EGF_2 PF07974.13 RUS86975.1 - 3.6e-08 33.6 42.4 2.9e-06 27.5 17.2 5.7 5 1 1 6 6 6 3 EGF-like domain Syndecan PF01034.20 RUS86975.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain I-EGF_1 PF18372.1 RUS86975.1 - 0.022 14.9 9.1 0.022 14.9 9.1 5.5 5 1 0 5 5 5 0 Integrin beta epidermal growth factor like domain 1 Viral_Beta_CD PF04530.12 RUS86975.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.7 3 2 1 4 4 4 0 Viral Beta C/D like family Integrin_beta PF00362.18 RUS86976.1 - 5.8e-77 258.7 0.0 8.3e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain PSI_integrin PF17205.3 RUS86976.1 - 1.8e-10 40.4 8.5 5.9e-10 38.7 8.5 2.0 1 0 0 1 1 1 1 Integrin plexin domain I-EGF_1 PF18372.1 RUS86976.1 - 2.8e-06 27.3 6.5 2.8e-06 27.3 6.5 2.8 2 1 0 2 2 2 1 Integrin beta epidermal growth factor like domain 1 Aldedh PF00171.22 RUS86977.1 - 1.5e-133 445.7 0.1 1.8e-133 445.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 7tm_2 PF00002.24 RUS86980.1 - 3.1e-12 46.3 0.1 4.1e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4381 PF14316.6 RUS86980.1 - 0.057 13.6 1.1 0.15 12.3 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NnrS PF05940.12 RUS86980.1 - 0.087 12.2 1.2 0.1 11.9 1.2 1.1 1 0 0 1 1 1 0 NnrS protein RRM_1 PF00076.22 RUS86982.1 - 2.9e-20 71.8 0.0 4.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS86982.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RUS86982.1 - 0.0039 16.8 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS86982.1 - 0.004 17.0 0.0 0.0068 16.2 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif CDC45 PF02724.14 RUS86982.1 - 6.8 4.9 15.9 23 3.1 15.9 1.7 1 1 0 1 1 1 0 CDC45-like protein SRTM1 PF15872.5 RUS86983.1 - 0.098 12.8 0.2 0.35 11.0 0.2 1.9 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 PLC-beta_C PF08703.10 RUS86986.1 - 1.3e-05 25.2 7.9 0.074 13.0 0.1 3.2 1 1 1 3 3 3 3 PLC-beta C terminal ApoLp-III PF07464.11 RUS86986.1 - 7.2e-05 22.9 0.0 0.055 13.6 0.0 2.3 1 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) FAM184 PF15665.5 RUS86986.1 - 0.00038 20.3 1.2 0.13 12.1 0.4 2.6 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B DUF4085 PF13315.6 RUS86986.1 - 0.0013 18.4 1.8 2.2 7.9 0.2 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF4085) DBINO PF13892.6 RUS86986.1 - 0.0021 18.4 14.0 0.59 10.5 1.4 3.0 1 1 1 2 2 2 2 DNA-binding domain Prominin PF05478.11 RUS86986.1 - 0.0083 14.1 0.4 0.87 7.5 0.3 2.2 1 1 1 2 2 2 2 Prominin Phasin_2 PF09361.10 RUS86986.1 - 0.01 16.1 0.0 18 5.7 0.0 3.4 3 1 1 4 4 3 0 Phasin protein Exonuc_VII_L PF02601.15 RUS86986.1 - 0.046 13.3 2.2 0.47 10.0 2.2 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit SAPIS-gp6 PF16722.5 RUS86986.1 - 0.052 14.0 13.8 20 5.6 0.2 4.9 1 1 4 7 7 7 0 Pathogenicity island protein gp6 in Staphylococcus BAR_3_WASP_bdg PF10456.9 RUS86986.1 - 0.064 12.7 0.1 9.5 5.6 0.0 3.1 1 1 3 4 4 4 0 WASP-binding domain of Sorting nexin protein DUF4423 PF14394.6 RUS86986.1 - 0.079 12.7 2.7 6.8 6.4 0.6 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4423) Prolamin_like PF05617.11 RUS86986.1 - 0.12 12.5 27.2 28 5.0 0.2 7.0 1 1 2 3 3 2 0 Prolamin-like DCB PF16213.5 RUS86986.1 - 0.12 12.0 0.8 5.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 PDH PF02153.17 RUS86986.1 - 0.18 10.7 2.9 8 5.4 0.2 3.1 1 1 2 4 4 4 0 Prephenate dehydrogenase TipAS PF07739.13 RUS86986.1 - 0.19 12.3 0.8 16 6.1 0.1 3.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain VPS28 PF03997.12 RUS86986.1 - 0.2 11.3 2.1 36 4.0 2.1 3.6 1 1 0 1 1 1 0 VPS28 protein zf-CCHC PF00098.23 RUS86986.1 - 0.32 11.2 57.4 56 4.1 0.2 15.6 16 0 0 16 16 16 0 Zinc knuckle GH3 PF03321.13 RUS86986.1 - 0.7 8.7 5.3 0.82 8.4 0.1 2.4 2 1 0 2 2 2 0 GH3 auxin-responsive promoter AIF-MLS PF14962.6 RUS86986.1 - 1.2 9.1 7.2 2.7 7.9 2.4 2.4 1 1 0 2 2 2 0 Mitochondria Localisation Sequence L_biotic_typeA PF04604.13 RUS86986.1 - 2.4 8.1 6.6 50 3.9 0.0 4.8 5 1 3 8 8 8 0 Type-A lantibiotic IDH PF03971.14 RUS86986.1 - 2.5 6.4 4.9 40 2.5 0.2 3.1 1 1 1 3 3 3 0 Monomeric isocitrate dehydrogenase Hydrolase_4 PF12146.8 RUS86987.1 - 0.23 10.7 3.0 2.7 7.2 2.7 2.4 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF5624 PF18538.1 RUS86987.1 - 0.73 9.9 15.6 9.9 6.3 3.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5624) CSN8_PSD8_EIF3K PF10075.9 RUS86987.1 - 1.3 9.0 9.7 5.6 6.9 2.3 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family DUF3067 PF11267.8 RUS86987.1 - 4.5 7.9 10.0 20 5.9 0.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3067) SF3A3 PF16837.5 RUS86987.1 - 6.8 7.3 11.9 35 5.0 5.5 2.6 1 1 1 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 MIX PF18529.1 RUS86988.1 - 0.0057 16.4 1.1 0.24 11.1 0.1 2.5 2 1 1 3 3 3 2 Mitochondrial membrane-anchored proteins F-box_5 PF18511.1 RUS86988.1 - 0.077 12.6 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 F-box DUF4218 PF13960.6 RUS86988.1 - 0.28 10.8 1.9 12 5.6 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4218) GPHR_N PF12537.8 RUS86989.1 - 0.091 12.9 10.5 16 5.6 0.1 4.1 1 1 3 4 4 4 0 The Golgi pH Regulator (GPHR) Family N-terminal MdcE PF06833.11 RUS86989.1 - 0.22 11.0 9.3 3.7 7.0 1.1 3.3 1 1 2 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) SDA1 PF05285.12 RUS86991.1 - 0.46 9.8 56.3 0.75 9.2 56.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS86991.1 - 2.2 6.4 55.6 3.8 5.6 55.6 1.3 1 0 0 1 1 1 0 Nop14-like family A2M_BRD PF07703.14 RUS86992.1 - 2.5e-05 24.7 0.2 1.7 9.0 0.2 4.5 1 1 0 1 1 1 1 Alpha-2-macroglobulin bait region domain S-AdoMet_synt_M PF02772.16 RUS86992.1 - 0.0014 18.8 3.9 1e+02 3.1 0.0 5.8 2 2 3 7 7 7 0 S-adenosylmethionine synthetase, central domain MeMO_Hyd_G PF02964.16 RUS86992.1 - 0.046 13.7 4.8 36 4.3 0.2 3.7 1 1 5 6 6 6 0 Methane monooxygenase, hydrolase gamma chain MliC PF09864.9 RUS86992.1 - 0.21 11.6 20.6 12 5.9 1.7 6.2 2 2 3 5 5 5 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF1964 PF09244.10 RUS86992.1 - 0.37 11.3 13.4 11 6.6 0.4 4.8 1 1 4 6 6 6 0 Domain of unknown function (DUF1964) PRODH PF18327.1 RUS86992.1 - 4 7.7 13.0 3.6e+02 1.5 0.0 6.6 7 0 0 7 7 7 0 Proline utilization A proline dehydrogenase N-terminal domain Gly-zipper_Omp PF13488.6 RUS86994.1 - 1e-22 79.8 94.8 0.11 12.5 27.7 6.3 1 1 1 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 RUS86994.1 - 6.9e-15 54.5 72.0 0.031 14.0 11.0 6.5 1 1 2 3 3 3 2 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 RUS86994.1 - 4.3e-11 42.5 99.2 9.3e+03 -3.4 39.1 7.0 1 1 1 2 2 2 0 Glycine zipper 2TM domain Transgly_assoc PF04226.13 RUS86994.1 - 3.8e-06 27.1 92.0 0.66 10.3 12.0 8.5 1 1 2 3 3 3 1 Transglycosylase associated protein Gly-zipper_OmpA PF13436.6 RUS86994.1 - 2.2e-05 24.2 69.8 1.8e+04 -48.1 69.8 7.0 1 1 0 1 1 1 0 Glycine-zipper domain DUF456 PF04306.13 RUS86994.1 - 0.00024 21.4 77.1 1.8e+04 -42.2 77.1 6.3 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Yae1_N PF09811.9 RUS86994.1 - 0.012 15.3 13.5 81 3.0 0.0 7.4 1 1 4 5 5 5 0 Essential protein Yae1, N terminal Fibrinogen_BP PF08017.11 RUS86994.1 - 0.018 13.5 3.4 0.023 13.1 3.4 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein MtrC PF04211.13 RUS86994.1 - 0.022 13.8 65.3 1.1e+02 1.6 19.7 5.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C Colicin_V PF02674.16 RUS86994.1 - 0.75 9.8 56.2 16 5.4 11.8 4.4 1 1 0 2 2 2 0 Colicin V production protein zf-C2H2_11 PF16622.5 RUS86995.1 - 0.021 14.5 1.9 0.036 13.8 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 RUS86995.1 - 0.61 10.7 0.1 0.61 10.7 0.1 3.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Thionin PF00321.17 RUS86996.1 - 0.33 11.5 6.9 6.7 7.3 0.2 3.0 1 1 2 3 3 3 0 Plant thionin zf-TFIIB PF13453.6 RUS86996.1 - 1.7 8.0 4.8 0.85 9.0 0.9 2.3 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2 PF00096.26 RUS86997.1 - 3.5e-28 96.5 67.5 1.4e-06 28.4 0.9 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS86997.1 - 1.2e-27 95.1 59.3 5.9e-08 32.8 0.6 9.8 10 0 0 10 10 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS86997.1 - 5.4e-27 92.1 64.1 7.7e-05 23.2 0.6 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 RUS86997.1 - 1.2e-16 60.5 51.3 0.0042 17.4 0.1 8.5 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS86997.1 - 2.3e-15 56.4 40.1 0.024 14.9 0.9 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS86997.1 - 6.2e-08 32.5 62.3 0.0079 16.2 0.9 8.6 9 0 0 9 9 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS86997.1 - 4.8e-07 30.1 44.4 0.064 13.6 1.5 8.1 3 3 5 8 8 8 4 C2H2 type zinc-finger (2 copies) BolA PF01722.18 RUS86997.1 - 0.021 15.1 6.1 12 6.3 0.1 3.6 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_3rep PF18868.1 RUS86997.1 - 0.036 14.7 19.5 0.29 11.8 2.7 4.1 3 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 RUS86997.1 - 0.04 13.8 5.1 2.4 8.0 0.1 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 RUS86997.1 - 0.072 12.9 0.2 0.072 12.9 0.2 8.1 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RUS86997.1 - 0.28 11.1 0.1 0.28 11.1 0.1 6.2 6 0 0 6 6 6 0 zinc-finger of a C2HC-type DUF3449 PF11931.8 RUS86997.1 - 0.62 9.8 8.1 2.8 7.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Rad50_zn_hook PF04423.14 RUS86997.1 - 0.68 9.8 4.7 11 6.0 0.0 3.9 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF3268 PF11672.8 RUS86997.1 - 0.82 10.0 10.5 24 5.3 1.5 3.3 3 0 0 3 3 3 0 zinc-finger-containing domain PHF5 PF03660.14 RUS86997.1 - 4.2 7.6 12.5 36 4.6 0.1 3.8 3 1 1 4 4 4 0 PHF5-like protein zf-C2HE PF16278.5 RUS86997.1 - 4.6 7.8 35.0 0.66 10.5 2.1 5.5 4 3 1 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 RUS86997.1 - 4.8 7.4 22.2 0.71 10.0 0.5 5.9 5 2 2 7 7 7 0 Zinc ribbon domain Nbl1_Borealin_N PF10444.9 RUS86998.1 - 0.00047 19.7 4.5 1.4 8.7 0.2 3.4 1 1 2 3 3 3 3 Nbl1 / Borealin N terminal Baculo_PEP_C PF04513.12 RUS86998.1 - 0.00069 19.7 11.7 0.0068 16.5 11.7 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2523 PF10734.9 RUS86998.1 - 0.0026 18.3 2.9 2.3 8.8 0.3 3.6 1 1 0 2 2 2 2 Protein of unknown function (DUF2523) DUF4906 PF16249.5 RUS86998.1 - 0.81 9.5 9.3 1.2 8.9 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4906) PAXX PF15384.6 RUS86998.1 - 0.9 9.2 15.0 14 5.3 7.1 3.3 1 1 2 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Baculo_PEP_N PF04512.12 RUS86998.1 - 1 9.7 5.6 40 4.5 0.3 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus HDV_ag PF01517.18 RUS86999.1 - 0.51 10.1 5.6 0.47 10.2 1.2 2.1 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen SDP_N PF12278.8 RUS86999.1 - 1.2 9.3 4.0 3.1 7.9 4.0 1.7 1 0 0 1 1 1 0 Sex determination protein N terminal Apolipoprotein PF01442.18 RUS87000.1 - 0.0053 16.7 0.3 0.0061 16.5 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain KMP11 PF03037.16 RUS87000.1 - 0.18 12.6 0.4 0.35 11.7 0.3 1.5 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 OrfB_Zn_ribbon PF07282.11 RUS87000.1 - 0.35 10.8 2.2 0.53 10.3 0.5 2.2 2 2 0 2 2 2 0 Putative transposase DNA-binding domain CitMHS PF03600.16 RUS87001.1 - 8e-05 22.0 0.1 9.4e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 Citrate transporter PHO4 PF01384.20 RUS87001.1 - 0.0074 15.4 0.0 0.0074 15.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Nop14 PF04147.12 RUS87001.1 - 0.057 11.6 37.0 0.068 11.4 37.0 1.1 1 0 0 1 1 1 0 Nop14-like family EI24 PF07264.11 RUS87001.1 - 0.085 13.1 7.3 0.12 12.7 7.3 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Halogen_Hydrol PF10112.9 RUS87001.1 - 0.26 11.3 8.3 1.6 8.7 8.3 1.9 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CbiQ PF02361.16 RUS87001.1 - 1.3 8.6 16.9 1.7 8.2 16.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein YfhO PF09586.10 RUS87001.1 - 1.4 7.0 8.5 1.7 6.8 8.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Phlebovirus_G1 PF07243.11 RUS87001.1 - 1.9 6.8 10.7 2.4 6.4 10.7 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Pex24p PF06398.11 RUS87001.1 - 7.2 5.5 12.0 3.1e+02 0.1 12.1 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin NPR3 PF03666.13 RUS87001.1 - 9.1 4.9 9.9 12 4.5 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Xan_ur_permease PF00860.20 RUS87004.1 - 6.6e-49 166.6 11.6 8.9e-49 166.2 11.6 1.2 1 0 0 1 1 1 1 Permease family Keratin_B2_2 PF13885.6 RUS87005.1 - 5.8e-06 26.2 62.8 0.0031 17.4 24.0 3.2 2 1 1 3 3 3 2 Keratin, high sulfur B2 protein PMG PF05287.12 RUS87005.1 - 3.6 7.6 40.4 3.2 7.8 16.9 2.0 1 1 1 2 2 2 0 PMG protein Syntaxin-5_N PF11416.8 RUS87006.1 - 4.3e-15 54.5 50.8 13 5.2 0.0 19.4 21 0 0 21 21 21 18 Syntaxin-5 N-terminal, Sly1p-binding domain Glyco_transf_4 PF13439.6 RUS87008.1 - 2.8e-08 34.0 7.5 0.78 9.7 0.2 5.5 1 1 4 5 5 5 5 Glycosyltransferase Family 4 DUF1612 PF07756.12 RUS87008.1 - 0.0021 18.3 2.2 15 5.9 0.1 4.7 2 2 3 5 5 5 1 Protein of unknown function (DUF1612) zf-LYAR PF08790.11 RUS87008.1 - 0.0048 16.8 28.1 2.8 7.9 0.5 10.1 11 0 0 11 11 11 1 LYAR-type C2HC zinc finger sCache_2 PF17200.4 RUS87008.1 - 5.5 6.8 28.0 6.6 6.6 0.6 5.5 2 2 5 7 7 7 0 Single Cache domain 2 SH3_4 PF06347.13 RUS87009.1 - 0.00014 21.6 15.4 3.6 7.5 0.1 5.3 5 0 0 5 5 5 3 Bacterial SH3 domain DUF2924 PF11149.8 RUS87009.1 - 0.00027 21.3 0.3 1.2e+02 3.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2924) SBF PF01758.16 RUS87009.1 - 0.0022 17.7 0.8 88 2.7 0.0 4.7 5 0 0 5 5 5 0 Sodium Bile acid symporter family DUF5540 PF17694.1 RUS87009.1 - 0.0091 16.5 0.1 1.9e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5540) PMR5N PF14416.6 RUS87009.1 - 0.015 15.6 3.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 PMR5 N terminal Domain ssDNA_TraI_N PF18272.1 RUS87009.1 - 0.54 10.3 6.3 2.3e+02 1.9 0.0 4.9 5 0 0 5 5 5 0 single-stranded DNA binding TraI N-terminal subdomain Acyl_CoA_thio PF02551.15 RUS87010.1 - 1.9e-19 69.8 0.2 2.3e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA thioesterase 4HBT_3 PF13622.6 RUS87010.1 - 1.5e-13 51.6 0.0 1.6e-13 51.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_21 PF05050.12 RUS87011.1 - 7e-09 35.9 0.0 9.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain TF_Zn_Ribbon PF08271.12 RUS87012.1 - 0.025 14.1 0.3 11 5.6 0.0 3.3 3 1 1 4 4 4 0 TFIIB zinc-binding Toxin-deaminase PF14424.6 RUS87012.1 - 0.05 13.7 3.1 2.9 8.0 2.0 3.5 2 1 1 4 4 4 0 The BURPS668_1122 family of deaminases VCPO_N PF17897.1 RUS87012.1 - 0.094 12.5 1.0 5.4 6.7 0.1 2.9 1 1 2 3 3 3 0 Vanadium chloroperoxidase N-terminal domain Extensin_2 PF04554.13 RUS87012.1 - 0.18 11.9 5.5 2 8.6 2.6 2.6 1 1 1 2 2 2 0 Extensin-like region Codanin-1_C PF15296.6 RUS87012.1 - 0.23 11.5 8.6 15 5.7 1.4 3.9 1 1 3 4 4 4 0 Codanin-1 C-terminus RRM_8 PF11835.8 RUS87012.1 - 0.29 11.3 12.9 13 6.1 0.2 4.4 1 1 3 4 4 4 0 RRM-like domain ORC4_C PF14629.6 RUS87012.1 - 0.65 9.3 8.4 6.9 6.0 0.4 3.0 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF4345 PF14248.6 RUS87013.1 - 1.6 8.6 21.7 3.8 7.4 4.3 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4345) Lem_TRP PF08262.11 RUS87013.1 - 5.3 7.3 13.9 4.6e+02 1.3 0.0 6.6 7 0 0 7 7 7 0 Leucophaea maderae tachykinin-related peptide DUF2347 PF09804.9 RUS87014.1 - 5.9e-73 245.9 0.0 8.3e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 RUS87014.1 - 8.3e-13 48.3 0.2 1.6e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 RUS87014.1 - 8.1e-12 44.5 0.7 1.8e-08 33.5 0.0 3.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF4484 PF14831.6 RUS87014.1 - 0.013 15.6 1.0 0.56 10.2 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4484) DUF1374 PF07118.11 RUS87014.1 - 0.12 12.9 0.9 0.28 11.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) DHHC PF01529.20 RUS87015.1 - 1.9e-30 105.7 10.0 1.9e-30 105.7 10.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4577 PF15145.6 RUS87015.1 - 1.5 8.8 0.0 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) COPR5 PF15340.6 RUS87015.1 - 3.4 8.3 6.6 15 6.2 2.1 2.6 1 1 1 2 2 2 0 Cooperator of PRMT5 family CxC3 PF18804.1 RUS87016.1 - 0.0013 18.6 4.6 34 4.3 0.1 4.9 1 1 5 6 6 6 6 CxC3 like cysteine cluster associated with KDZ transposases Defensin_RK-1 PF17860.1 RUS87016.1 - 0.063 13.8 12.9 1.9e+02 2.6 0.0 6.5 1 1 6 7 7 7 0 RK-1-like defensin Waikav_capsid_1 PF12264.8 RUS87016.1 - 0.27 10.7 2.4 31 4.0 0.1 2.8 1 1 3 4 4 4 0 Waikavirus capsid protein 1 DUF1543 PF07566.12 RUS87016.1 - 1.9 8.3 8.1 4.8e+02 0.6 0.0 5.8 7 0 0 7 7 7 0 Domain of Unknown Function (DUF1543) DUF1279 PF06916.13 RUS87017.1 - 2.2e-21 76.2 0.4 3.7e-21 75.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Alpha-amyl_C PF09071.10 RUS87018.1 - 0.013 15.3 0.2 15 5.5 0.0 3.1 1 1 3 4 4 4 0 Alpha-amylase, C terminal RCC1_2 PF13540.6 RUS87018.1 - 0.07 12.9 12.1 12 5.8 0.1 5.1 6 0 0 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat Phage_pRha PF09669.10 RUS87018.1 - 0.11 13.1 5.6 21 5.8 0.2 4.4 1 1 3 4 4 4 0 Phage regulatory protein Rha (Phage_pRha) Glyco_hydro_67M PF07488.12 RUS87018.1 - 0.16 11.1 0.1 13 4.7 0.0 2.5 1 1 2 3 3 3 0 Glycosyl hydrolase family 67 middle domain FRD2 PF03197.13 RUS87018.1 - 0.67 10.3 15.1 0.68 10.3 1.7 3.1 1 1 2 3 3 3 0 Bacteriophage FRD2 protein DUF3630 PF12305.8 RUS87018.1 - 0.8 9.8 4.7 96 3.2 0.1 3.7 1 1 3 5 5 5 0 Protein of unknown function (DUF3630) OTU PF02338.19 RUS87019.1 - 2.6e-18 66.7 0.1 3.6e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RUS87019.1 - 0.00044 19.8 0.0 0.00048 19.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF4632 PF15451.6 RUS87019.1 - 6.6 6.9 6.1 2.9 8.0 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) zf_C2HC_14 PF18574.1 RUS87020.1 - 1.6e-12 47.0 3.9 30 4.5 0.0 9.2 9 0 0 9 9 9 9 C2HC Zing finger domain DASH_Hsk3 PF08227.11 RUS87020.1 - 0.0006 20.1 15.9 83 3.7 0.1 8.3 1 1 4 7 7 7 0 DASH complex subunit Hsk3 like YmaF PF12788.7 RUS87020.1 - 0.035 14.6 1.4 86 3.8 0.1 3.5 1 1 4 5 5 5 0 YmaF family PPTA PF01239.22 RUS87021.1 - 5.8e-40 133.9 11.6 9.8e-09 34.7 0.7 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RabGGT_insert PF07711.11 RUS87021.1 - 3e-05 24.4 0.3 5.3e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 Rab geranylgeranyl transferase alpha-subunit, insert domain EF-hand_7 PF13499.6 RUS87022.1 - 3.2e-14 53.1 0.5 6.7e-09 36.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS87022.1 - 5.1e-12 44.7 0.2 2.6e-05 23.8 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RUS87022.1 - 1e-08 34.1 6.9 1.2e-05 24.5 0.0 4.2 5 0 0 5 5 5 2 EF hand EFhand_Ca_insen PF08726.10 RUS87022.1 - 5.4e-07 29.6 0.8 1.1e-06 28.6 0.8 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 RUS87022.1 - 8.9e-07 29.2 0.3 0.055 13.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS87022.1 - 6.8e-06 25.8 0.8 5e-05 23.1 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS87022.1 - 0.00058 19.2 0.0 0.00058 19.2 0.0 2.2 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 RUS87022.1 - 0.038 14.3 0.4 6.3 7.2 0.0 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PGBA_N PF15436.6 RUS87022.1 - 0.041 13.5 0.0 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA N-terminal Ldh_1_C PF02866.18 RUS87023.1 - 5.7e-42 143.5 0.3 1.9e-41 141.8 0.2 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RUS87023.1 - 1.5e-36 125.5 2.4 3.4e-35 121.2 1.0 2.3 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain PE-PPE PF08237.11 RUS87023.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain KORA PF16509.5 RUS87023.1 - 0.043 14.1 0.4 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor zf-HC5HC2H PF13771.6 RUS87024.1 - 2e-15 56.8 9.0 2e-15 56.8 9.0 3.9 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RUS87024.1 - 2.4e-06 27.7 8.8 2.4e-06 27.7 8.8 3.4 2 1 2 4 4 4 2 PHD-zinc-finger like domain ATP-synt_8 PF00895.20 RUS87025.1 - 2.6 8.6 6.8 2 8.9 0.9 2.5 3 0 0 3 3 3 0 ATP synthase protein 8 RBD PF02196.15 RUS87027.1 - 8.1e-09 35.4 0.2 0.00018 21.5 0.1 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain Cobl PF09469.10 RUS87027.1 - 1.5e-08 34.7 0.0 2.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Cordon-bleu ubiquitin-like domain DUF4677 PF15726.5 RUS87027.1 - 0.025 14.7 1.3 0.092 12.9 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) CorA PF01544.18 RUS87027.1 - 4.3 6.6 5.6 7 5.9 5.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CoA_transf_3 PF02515.17 RUS87028.1 - 1.3e-127 425.9 0.0 1.5e-127 425.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 RUS87028.1 - 0.12 12.3 0.0 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) VRR_NUC PF08774.11 RUS87029.1 - 2.9e-21 75.6 0.0 7.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain HECT_2 PF09814.9 RUS87030.1 - 2.6e-31 108.8 2.5 3.9e-31 108.3 2.5 1.3 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Phlebovirus_G2 PF07245.11 RUS87030.1 - 0.026 13.0 0.6 0.037 12.5 0.6 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 CrgA PF06781.12 RUS87031.1 - 0.0091 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Cell division protein CrgA DUF4381 PF14316.6 RUS87031.1 - 0.16 12.2 0.7 0.46 10.7 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PV-1 PF06637.11 RUS87031.1 - 0.19 10.5 0.3 0.28 10.0 0.3 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) TMEM52 PF14979.6 RUS87031.1 - 0.32 10.9 7.5 0.54 10.2 2.8 2.6 1 1 1 2 2 2 0 Transmembrane 52 RCR PF12273.8 RUS87031.1 - 0.69 10.6 4.4 4.3 8.0 4.4 2.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red BNIP3 PF06553.12 RUS87032.1 - 2.3e-27 95.9 4.6 3.7e-27 95.3 4.6 1.3 1 0 0 1 1 1 1 BNIP3 zf-RING_2 PF13639.6 RUS87033.1 - 7e-11 42.3 9.3 7e-11 42.3 9.3 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 RUS87033.1 - 1.5e-07 31.0 5.0 1.5e-07 31.0 5.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RUS87033.1 - 1.9e-06 27.6 9.7 1.9e-06 27.6 9.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS87033.1 - 2.8e-06 27.1 8.0 2.8e-06 27.1 8.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS87033.1 - 5e-06 26.7 6.8 5e-06 26.7 6.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RUS87033.1 - 2.8e-05 24.0 7.6 2.8e-05 24.0 7.6 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 RUS87033.1 - 6.2e-05 22.9 6.2 6.2e-05 22.9 6.2 3.3 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS87033.1 - 7.8e-05 22.5 5.6 7.8e-05 22.5 5.6 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RUS87033.1 - 0.00024 21.1 3.6 0.0011 19.0 3.6 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RUS87033.1 - 0.00027 20.5 6.7 0.00027 20.5 6.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type SAP PF02037.27 RUS87033.1 - 0.1 12.4 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 SAP domain RINGv PF12906.7 RUS87033.1 - 3.1 8.0 7.2 11 6.2 7.2 2.1 1 0 0 1 1 1 0 RING-variant domain LysM PF01476.20 RUS87034.1 - 4.9e-05 23.3 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain Fusion_F0 PF13044.6 RUS87034.1 - 0.4 9.3 1.4 0.59 8.7 1.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus RNA_pol_3_Rpc31 PF11705.8 RUS87035.1 - 8.9e-32 111.2 11.3 8.9e-32 111.2 11.3 1.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Afi1 PF07792.12 RUS87035.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.5 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DARPP-32 PF05395.12 RUS87035.1 - 0.13 12.5 10.4 0.17 12.1 10.4 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4471 PF14740.6 RUS87035.1 - 0.24 10.6 5.5 0.32 10.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) BUD22 PF09073.10 RUS87035.1 - 0.33 10.2 19.7 0.42 9.9 19.7 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 RUS87035.1 - 0.6 9.4 16.8 0.81 9.0 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.12 RUS87035.1 - 2.9 7.6 18.8 4.3 7.0 18.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 RUS87035.1 - 6.7 5.4 4.9 8.1 5.1 4.9 1.0 1 0 0 1 1 1 0 Presenilin Slu7 PF11708.8 RUS87036.1 - 1.3e-100 336.6 17.9 1.3e-100 336.6 17.9 2.9 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor DUF755 PF05501.11 RUS87036.1 - 0.0057 16.9 30.8 0.0057 16.9 30.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF755) zf-CCHC_4 PF14392.6 RUS87036.1 - 0.07 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-ACC PF17848.1 RUS87036.1 - 0.26 11.4 1.6 2.5 8.3 0.3 2.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain GREB1 PF15782.5 RUS87036.1 - 0.33 8.0 8.7 0.49 7.5 8.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCHC PF00098.23 RUS87036.1 - 0.39 10.9 3.2 0.74 10.0 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3854 PF12965.7 RUS87036.1 - 0.89 9.5 3.7 0.78 9.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) LRIF1 PF15741.5 RUS87036.1 - 9.9 4.6 21.2 23 3.3 21.2 1.6 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 FAM221 PF14753.6 RUS87037.1 - 5.4e-27 94.7 7.8 1.2e-16 60.9 0.8 2.1 2 0 0 2 2 2 2 Protein FAM221A/B RAP1 PF07218.11 RUS87037.1 - 0.49 8.6 5.2 0.62 8.3 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ubiquitin_2 PF14560.6 RUS87038.1 - 7.5e-25 87.2 0.0 1.7e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 RUS87038.1 - 1.1e-24 86.2 2.5 2e-24 85.3 2.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain T6_Ig_like PF18002.1 RUS87038.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 T6 antigen Ig like domain ubiquitin PF00240.23 RUS87038.1 - 0.13 12.0 0.0 0.9 9.3 0.0 2.4 1 1 0 1 1 1 0 Ubiquitin family WD40 PF00400.32 RUS87039.1 - 4.1e-10 40.1 19.3 0.00012 22.8 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 RUS87039.1 - 1.1e-05 24.3 4.7 0.022 13.4 0.5 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 RUS87039.1 - 0.065 12.9 1.4 0.72 9.5 0.1 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.25 RUS87040.1 - 1.6e-70 237.5 0.0 2.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87040.1 - 1e-31 110.2 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS87040.1 - 1e-06 28.3 0.0 2.5e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 RUS87040.1 - 0.031 13.9 0.1 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 RUS87040.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family dsDNA_bind PF01984.20 RUS87041.1 - 8.7e-31 106.5 11.0 1e-30 106.3 11.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SYF2 PF08231.12 RUS87041.1 - 0.069 13.6 2.0 0.09 13.2 2.0 1.2 1 0 0 1 1 1 0 SYF2 splicing factor EF-1_beta_acid PF10587.9 RUS87041.1 - 0.11 13.0 1.8 0.11 13.0 1.8 2.7 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region DUF4570 PF15134.6 RUS87041.1 - 0.16 12.0 5.5 0.043 13.8 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Paramecium_SA PF01508.16 RUS87042.1 - 1.8 9.0 14.8 20 5.7 2.0 3.5 1 1 2 3 3 3 0 Paramecium surface antigen domain EnY2 PF10163.9 RUS87043.1 - 1.3e-34 118.4 0.6 1.6e-34 118.1 0.6 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DED PF01335.21 RUS87043.1 - 0.021 15.1 1.4 0.45 10.8 0.1 2.5 2 2 0 2 2 2 0 Death effector domain DUF2294 PF10057.9 RUS87043.1 - 0.076 13.2 0.6 0.64 10.2 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) SAP PF02037.27 RUS87043.1 - 6.6 6.6 11.6 8.6 6.2 0.2 4.1 4 1 0 4 4 4 0 SAP domain Transglut_N PF00868.20 RUS87044.1 - 1.1e-30 106.4 0.0 2.5e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 RUS87044.1 - 6.5e-14 52.3 0.1 1.3e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 RUS87044.1 - 8.4e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family, C-terminal ig like domain NPCBM_assoc PF10633.9 RUS87044.1 - 0.1 12.8 1.9 0.54 10.5 0.0 3.0 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase AAA_12 PF13087.6 RUS87045.1 - 3.8e-43 147.4 0.4 7e-43 146.6 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS87045.1 - 2.8e-28 99.4 0.1 8.6e-14 51.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RUS87045.1 - 2.7e-08 34.3 0.0 0.0002 21.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 RUS87045.1 - 7.8e-07 29.0 0.0 0.0064 16.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RUS87045.1 - 0.00086 19.6 0.1 0.045 14.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 RUS87045.1 - 0.002 17.4 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RUS87045.1 - 0.0022 18.0 0.1 0.0071 16.4 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Osmo_CC PF08946.10 RUS87045.1 - 0.095 13.0 1.2 2.5 8.4 0.1 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil AAA_16 PF13191.6 RUS87045.1 - 0.25 11.7 4.3 0.38 11.1 0.1 3.1 2 2 0 2 2 2 0 AAA ATPase domain Pyr_redox_3 PF13738.6 RUS87046.1 - 4.9e-10 39.1 0.0 0.00026 20.4 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS87046.1 - 0.00085 18.6 0.0 0.0022 17.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS87046.1 - 0.041 13.0 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Presenilin PF01080.17 RUS87047.1 - 2.2 7.0 37.4 3 6.5 37.4 1.3 1 0 0 1 1 1 0 Presenilin CAC1F_C PF16885.5 RUS87047.1 - 9.6 5.7 17.4 11 5.5 17.4 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF4734 PF15881.5 RUS87048.1 - 3.3 8.0 6.3 10 6.4 6.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) Tetraspanin PF00335.20 RUS87049.1 - 2.3e-44 151.8 15.2 2.7e-44 151.6 15.2 1.0 1 0 0 1 1 1 1 Tetraspanin family 4HB_MCP_1 PF12729.7 RUS87049.1 - 9.4 5.7 5.9 2.7 7.5 0.6 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Ins145_P3_rec PF08709.11 RUS87050.1 - 3e-26 92.0 1.8 3.1e-25 88.6 0.4 2.6 2 1 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 RUS87050.1 - 1.7e-21 76.6 0.7 1.7e-21 76.6 0.7 1.8 2 0 0 2 2 2 1 RIH domain MIR PF02815.19 RUS87050.1 - 4.8e-16 59.1 3.3 3e-11 43.5 0.2 3.4 2 1 0 2 2 2 2 MIR domain RIH_assoc PF08454.11 RUS87051.1 - 2.1e-21 75.7 0.7 5.6e-21 74.3 0.7 1.7 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 RUS87051.1 - 1.1e-10 41.2 12.9 2.4e-10 40.1 12.9 1.6 1 0 0 1 1 1 1 Ion transport protein DUF5056 PF16479.5 RUS87051.1 - 0.02 15.1 0.9 2.4 8.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) SPT16 PF08644.11 RUS87051.1 - 0.49 10.6 3.9 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) VWA PF00092.28 RUS87052.1 - 3.2e-76 255.5 0.3 5.2e-44 150.6 0.4 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 RUS87052.1 - 4.2e-32 111.0 0.0 3e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWC PF00093.18 RUS87052.1 - 3.5e-09 36.8 84.6 0.002 18.4 14.0 5.7 5 0 0 5 5 5 4 von Willebrand factor type C domain VWA_3 PF13768.6 RUS87052.1 - 7.2e-09 35.8 0.1 5.3e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain ShK PF01549.24 RUS87052.1 - 3.4e-05 24.3 22.0 0.00085 19.8 8.4 5.7 6 1 0 6 6 6 3 ShK domain-like Copine PF07002.16 RUS87052.1 - 0.00037 20.0 0.3 0.0011 18.4 0.1 1.8 2 0 0 2 2 2 1 Copine VWA_CoxE PF05762.14 RUS87052.1 - 0.011 15.1 2.3 0.034 13.5 0.1 2.5 4 0 0 4 4 4 0 VWA domain containing CoxE-like protein VWC PF00093.18 RUS87053.1 - 2.5e-09 37.3 73.1 0.00074 19.8 13.5 4.2 4 0 0 4 4 4 4 von Willebrand factor type C domain DUF1496 PF07383.12 RUS87053.1 - 0.0007 19.1 3.4 0.46 10.1 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) Cytomega_UL20A PF05984.12 RUS87053.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein VWC PF00093.18 RUS87054.1 - 7.4e-13 48.6 251.0 0.0061 16.9 15.0 12.8 13 0 0 13 13 13 12 von Willebrand factor type C domain VWC PF00093.18 RUS87055.1 - 2.6e-05 24.4 33.7 0.0011 19.2 14.2 3.8 3 1 0 3 3 3 2 von Willebrand factor type C domain ShK PF01549.24 RUS87055.1 - 0.00031 21.2 20.6 0.0015 19.0 5.1 4.5 4 1 0 4 4 4 2 ShK domain-like fn1 PF00039.18 RUS87055.1 - 0.39 10.9 16.0 1.9 8.7 5.2 3.0 2 1 0 2 2 2 0 Fibronectin type I domain SBF PF01758.16 RUS87056.1 - 2.2e-27 96.0 17.0 2.2e-27 96.0 17.0 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family zf-nanos PF05741.13 RUS87057.1 - 3e-20 72.2 7.7 6e-20 71.2 7.7 1.5 1 0 0 1 1 1 1 Nanos RNA binding domain zf-CCHC_2 PF13696.6 RUS87057.1 - 0.023 14.5 1.5 0.023 14.5 1.5 2.1 2 1 0 2 2 2 0 Zinc knuckle Metaviral_G PF09595.10 RUS87057.1 - 0.15 12.1 5.7 0.045 13.8 2.2 1.9 2 0 0 2 2 2 0 Metaviral_G glycoprotein SSF PF00474.17 RUS87058.1 - 9.1e-40 136.8 17.5 9.1e-40 136.8 17.5 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family RhodobacterPufX PF11511.8 RUS87058.1 - 0.014 15.0 0.6 0.014 15.0 0.6 2.5 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Prenyltrans PF00432.21 RUS87058.1 - 0.058 13.1 0.5 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Innexin PF00876.18 RUS87059.1 - 5.8e-15 55.4 2.6 3.1e-13 49.8 0.0 2.6 3 0 0 3 3 3 2 Innexin CstA PF02554.14 RUS87059.1 - 2.6 6.9 6.0 0.13 11.2 0.7 1.5 2 0 0 2 2 2 0 Carbon starvation protein CstA Miga PF10265.9 RUS87060.1 - 2.8e-49 168.5 0.1 3.2e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 Mitoguardin BTB PF00651.31 RUS87062.1 - 1.6e-26 92.7 0.1 3.1e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS87062.1 - 1e-10 41.6 0.2 1.4e-09 38.0 0.1 2.8 2 1 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 RUS87062.1 - 0.00034 20.7 0.0 0.0028 17.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) Smim3 PF17307.2 RUS87063.1 - 1.6 8.3 7.7 1.3e+02 2.1 0.0 4.6 5 0 0 5 5 5 0 Small integral membrane protein 3 GOLGA2L5 PF15070.6 RUS87064.1 - 5.5e-91 306.1 71.6 1.2e-47 163.0 35.4 5.4 2 1 3 5 5 5 3 Putative golgin subfamily A member 2-like protein 5 PIN_4 PF13638.6 RUS87065.1 - 1.2e-30 106.5 0.1 1.2e-30 106.5 0.1 2.9 4 0 0 4 4 4 1 PIN domain WW PF00397.26 RUS87065.1 - 8.5e-09 35.4 0.5 2.1e-08 34.1 0.5 1.7 1 0 0 1 1 1 1 WW domain PIN_12 PF16289.5 RUS87065.1 - 0.0013 19.3 0.0 0.0013 19.3 0.0 3.6 4 1 1 5 5 5 1 PIN domain PIN_3 PF13470.6 RUS87065.1 - 0.0032 18.2 0.0 0.0067 17.2 0.0 1.6 1 0 0 1 1 1 1 PIN domain Glyco_hyd_101C PF17451.2 RUS87065.1 - 0.0048 17.2 0.2 0.037 14.3 0.2 2.6 1 0 0 1 1 1 1 Glycosyl hydrolase 101 beta sandwich domain RabGAP-TBC PF00566.18 RUS87069.1 - 2.2e-32 112.5 10.6 2e-30 106.1 0.9 3.0 2 1 0 2 2 2 2 Rab-GTPase-TBC domain V-ATPase_G PF03179.15 RUS87071.1 - 6.3e-22 78.1 17.2 7.5e-22 77.9 17.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CSRNP_N PF16019.5 RUS87071.1 - 0.32 10.9 4.5 0.36 10.7 4.5 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Mnd1 PF03962.15 RUS87071.1 - 0.85 9.9 4.8 1.2 9.4 0.2 2.4 2 1 1 3 3 3 0 Mnd1 HTH domain TROVE PF05731.11 RUS87072.1 - 7.1e-20 71.5 5.6 7.5e-19 68.1 0.7 3.2 2 1 1 3 3 3 1 TROVE domain DUF2914 PF11141.8 RUS87072.1 - 0.095 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Orn_DAP_Arg_deC PF00278.22 RUS87072.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ras PF00071.22 RUS87074.1 - 1.9e-15 56.8 0.1 2.9e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RUS87074.1 - 5.7e-11 42.7 0.3 6.2e-08 32.9 0.2 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS87074.1 - 2.6e-08 33.5 0.1 6.2e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS87074.1 - 7.8e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS87074.1 - 0.025 14.0 0.0 0.062 12.7 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4600 PF15372.6 RUS87074.1 - 0.035 14.6 1.1 0.058 13.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) PH_RBD PF12068.8 RUS87075.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 Rab-binding domain (RBD) SOG2 PF10428.9 RUS87075.1 - 3.2 6.8 14.4 3.6 6.7 14.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PDZ PF00595.24 RUS87078.1 - 9.7e-05 22.6 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS87078.1 - 0.0018 18.1 0.1 0.0042 16.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain EF-hand_1 PF00036.32 RUS87079.1 - 3.4e-13 48.1 4.7 3e-07 29.5 1.7 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS87079.1 - 5.3e-11 41.5 0.9 6.9e-07 28.7 0.8 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS87079.1 - 2.6e-09 37.4 3.8 5e-09 36.5 1.3 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS87079.1 - 0.00019 21.2 4.7 0.0056 16.5 0.7 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS87079.1 - 0.0002 20.7 0.9 0.0002 20.7 0.9 2.2 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 RUS87079.1 - 0.022 15.1 0.2 0.045 14.1 0.2 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RUS87079.1 - 0.047 13.7 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DDE_Tnp_IS66_C PF13817.6 RUS87079.1 - 0.052 13.8 0.0 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 IS66 C-terminal element Abhydrolase_1 PF00561.20 RUS87080.1 - 2.2e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS87080.1 - 0.00087 19.9 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 RUS87080.1 - 0.08 12.9 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PMT PF02366.18 RUS87081.1 - 1.4e-71 241.0 17.8 2.7e-71 240.0 17.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 RUS87081.1 - 4.9e-50 169.9 13.0 4.9e-50 169.9 13.0 2.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 RUS87081.1 - 1.3e-17 64.2 1.0 2.1e-17 63.6 1.0 1.3 1 0 0 1 1 1 1 MIR domain AlbA_2 PF04326.14 RUS87082.1 - 0.018 15.3 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Putative DNA-binding domain Mito_fiss_reg PF05308.11 RUS87082.1 - 0.091 12.8 1.3 0.13 12.3 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Malectin_like PF12819.7 RUS87082.1 - 0.2 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Malectin-like domain DUF4349 PF14257.6 RUS87082.1 - 0.23 10.9 1.8 0.33 10.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TUDOR PF00567.24 RUS87083.1 - 7e-09 35.8 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Tudor domain RRM_1 PF00076.22 RUS87084.1 - 7.6e-56 185.9 0.1 1.7e-17 63.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS87084.1 - 4.8e-08 32.6 0.2 1e-05 25.1 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS87084.1 - 0.0034 17.2 0.0 4.3 7.3 0.0 2.7 2 1 0 2 2 2 2 Occluded RNA-recognition motif RNA_bind PF08675.11 RUS87084.1 - 0.0045 17.0 0.0 0.044 13.8 0.0 2.5 2 2 0 2 2 2 1 RNA binding domain LupA PF18242.1 RUS87084.1 - 0.13 11.9 0.0 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Legionella ubiquitin-specific protease A domain SET_assoc PF11767.8 RUS87084.1 - 0.15 11.7 0.0 4.4 7.0 0.0 2.8 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 RUS87084.1 - 0.15 12.1 0.1 12 6.0 0.0 3.0 2 1 2 4 4 4 0 RNA binding motif PRK PF00485.18 RUS87085.1 - 3.7e-36 124.7 0.0 4.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 RUS87085.1 - 5.9e-06 26.9 0.2 2.7e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RUS87085.1 - 0.00011 22.6 0.8 0.092 13.2 0.1 2.4 2 1 0 2 2 2 2 AAA domain CoaE PF01121.20 RUS87085.1 - 0.00015 21.5 0.5 0.00044 20.0 0.5 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 RUS87085.1 - 0.0024 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 RUS87085.1 - 0.0032 17.6 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RUS87085.1 - 0.0068 16.2 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase T2SSE PF00437.20 RUS87085.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 RUS87086.1 - 1.9e-30 105.8 0.0 4.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS87086.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS87086.1 - 6.3e-05 22.5 0.5 0.00037 20.0 0.5 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 RUS87086.1 - 0.00056 19.5 1.3 0.00093 18.8 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D2 PF03144.25 RUS87086.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 PduV-EutP PF10662.9 RUS87086.1 - 0.055 13.2 0.4 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 RUS87086.1 - 0.076 12.4 0.3 0.22 10.9 0.3 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS87086.1 - 0.42 10.5 6.5 0.48 10.3 0.1 2.9 3 0 0 3 3 3 0 RsgA GTPase Pkinase_Tyr PF07714.17 RUS87087.1 - 5.5e-57 193.0 0.0 1.1e-56 192.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 RUS87087.1 - 1.7e-53 179.2 14.5 8.1e-15 55.2 1.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 RUS87087.1 - 2.1e-47 161.7 0.0 3.3e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 RUS87087.1 - 6e-46 154.3 12.0 1.5e-12 47.8 0.2 7.8 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 RUS87087.1 - 7.7e-45 149.5 19.5 4.4e-06 26.9 0.2 11.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 RUS87087.1 - 2.9e-42 137.8 7.6 0.00082 19.6 0.0 10.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS87087.1 - 2.2e-36 123.4 6.2 1e-08 35.3 0.0 8.8 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Kdo PF06293.14 RUS87087.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS87087.1 - 0.0081 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS87087.1 - 0.0097 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain zf-C2H2 PF00096.26 RUS87089.1 - 8.6e-20 70.0 27.8 1.4e-05 25.3 1.4 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS87089.1 - 9.3e-20 70.1 30.1 3.2e-07 30.5 2.1 5.2 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS87089.1 - 1.8e-13 50.0 34.3 0.00036 21.1 1.4 5.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS87089.1 - 2.1e-07 30.8 21.7 0.004 17.1 2.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS87089.1 - 1.4e-05 25.2 11.2 0.22 11.8 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 RUS87089.1 - 0.00012 22.0 17.3 0.15 12.1 2.8 4.4 2 1 2 4 4 4 2 BED zinc finger zf-Di19 PF05605.12 RUS87089.1 - 0.00015 22.0 4.1 0.00015 22.0 4.1 3.6 3 1 1 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 RUS87089.1 - 0.00078 19.3 14.4 0.098 12.6 0.1 4.4 4 0 0 4 4 4 1 LYAR-type C2HC zinc finger Prok-RING_1 PF14446.6 RUS87089.1 - 0.0034 17.3 7.2 5.9 6.9 0.1 4.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 RUS87089.1 - 0.015 15.4 1.1 0.015 15.4 1.1 3.9 4 1 0 4 4 2 0 Zinc ribbon domain zf-CHCC PF10276.9 RUS87089.1 - 0.024 14.7 6.3 0.26 11.4 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.7 RUS87089.1 - 0.025 14.9 15.3 2.6 8.4 9.3 4.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RUS87089.1 - 0.027 14.9 17.9 0.49 10.9 0.9 4.8 2 1 3 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 RUS87089.1 - 0.096 12.5 4.2 2.1 8.2 0.0 3.2 1 1 2 3 3 3 0 GAGA factor DUF4379 PF14311.6 RUS87089.1 - 0.12 12.8 5.4 0.47 10.9 0.2 3.2 2 1 1 3 3 3 0 Probable Zinc-ribbon domain zf-C2H2_3rep PF18868.1 RUS87089.1 - 0.31 11.7 11.8 19 6.0 0.8 3.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 RUS87089.1 - 0.38 10.4 18.5 0.66 9.6 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 RUS87089.1 - 0.4 11.2 5.3 16 6.1 0.4 4.1 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain FYDLN_acid PF09538.10 RUS87089.1 - 0.47 11.2 5.7 52 4.6 2.6 3.7 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) XPA_N PF01286.18 RUS87089.1 - 1.7 8.8 12.5 12 6.1 0.4 4.3 4 0 0 4 4 4 0 XPA protein N-terminal HNH_5 PF14279.6 RUS87089.1 - 1.9 8.4 10.4 20 5.2 0.5 4.3 3 1 0 3 3 3 0 HNH endonuclease DUF2072 PF09845.9 RUS87089.1 - 2 8.7 9.6 0.14 12.5 1.3 2.6 2 1 0 2 2 2 0 Zn-ribbon containing protein HypA PF01155.19 RUS87089.1 - 2.4 8.2 12.3 0.29 11.2 0.6 2.8 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC_2 PF13913.6 RUS87089.1 - 2.5 8.1 19.0 0.61 10.1 1.4 4.1 4 0 0 4 4 3 0 zinc-finger of a C2HC-type LIM PF00412.22 RUS87089.1 - 4 7.8 12.8 5.3 7.4 3.3 3.4 1 1 2 3 3 3 0 LIM domain DUF3268 PF11672.8 RUS87089.1 - 6.3 7.2 7.3 9.5 6.6 1.5 2.7 1 1 3 4 4 4 0 zinc-finger-containing domain zf_ZIC PF18366.1 RUS87089.1 - 9.2 6.5 7.2 15 5.7 0.2 3.6 2 1 2 4 4 4 0 Zic proteins zinc finger domain CCSAP PF15748.5 RUS87090.1 - 1.7e-18 67.8 27.9 2e-14 54.4 27.9 2.2 1 1 0 1 1 1 1 Centriole, cilia and spindle-associated GREB1 PF15782.5 RUS87090.1 - 1.5 5.9 11.9 2 5.5 11.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer adh_short PF00106.25 RUS87091.1 - 3.9e-32 111.3 0.1 4.4e-31 107.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS87091.1 - 5.3e-19 68.7 0.0 1.6e-18 67.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS87091.1 - 9.4e-07 28.9 0.1 1.7e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 KR domain XRN1_D2_D3 PF18334.1 RUS87092.1 - 0.65 10.2 4.3 42 4.5 0.1 3.5 1 1 2 4 4 4 0 Exoribonuclease Xrn1 D2/D3 domain Pkinase PF00069.25 RUS87093.1 - 4.9e-70 235.9 0.0 8.6e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87093.1 - 8.2e-36 123.6 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RUS87093.1 - 5.1e-26 90.3 23.1 4.2e-13 49.0 9.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 RUS87093.1 - 1.8e-07 30.8 0.0 5.3e-07 29.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like C1_2 PF03107.16 RUS87093.1 - 7.2e-07 29.4 17.0 0.0011 19.2 3.3 2.8 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 RUS87093.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS87093.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 RUS87093.1 - 0.059 13.3 20.1 0.52 10.2 3.9 2.5 2 0 0 2 2 2 0 PHD-finger ABC1 PF03109.16 RUS87093.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family FYVE_2 PF02318.16 RUS87093.1 - 0.63 10.3 13.2 1.3 9.3 5.8 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_9 PF13901.6 RUS87093.1 - 0.81 9.6 18.6 0.89 9.5 4.0 2.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 RUS87093.1 - 2.2 7.9 13.0 0.37 10.4 1.2 2.7 2 0 0 2 2 2 0 PHD-finger RIO1 PF01163.22 RUS87093.1 - 4.4 6.8 8.5 0.059 13.0 0.3 1.9 2 0 0 2 2 2 0 RIO1 family Prok-RING_1 PF14446.6 RUS87093.1 - 4.9 7.2 17.1 1.8 8.5 3.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 RUS87094.1 - 9.8e-06 25.4 12.4 2.4e-05 24.1 12.4 1.7 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RUS87094.1 - 0.0059 16.5 2.9 0.0059 16.5 2.9 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Macoilin PF09726.9 RUS87094.1 - 0.42 9.1 5.5 0.63 8.5 5.5 1.3 1 1 0 1 1 1 0 Macoilin family zf-HC5HC2H PF13771.6 RUS87094.1 - 0.77 10.1 10.4 0.28 11.5 6.2 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_2 PF03107.16 RUS87094.1 - 5.3 7.4 12.2 2 8.8 5.1 2.5 2 0 0 2 2 2 0 C1 domain EF1G PF00647.19 RUS87095.1 - 3.6e-38 129.9 0.3 8.3e-38 128.7 0.3 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 RUS87095.1 - 3.8e-15 55.9 0.0 9.5e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS87095.1 - 9e-10 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS87095.1 - 2.9e-09 37.0 0.1 7.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain AHSP PF09236.10 RUS87095.1 - 0.024 15.1 0.1 14 6.3 0.1 2.9 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Pox_Ag35 PF03286.14 RUS87095.1 - 0.039 13.8 2.0 0.066 13.0 2.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2201_N PF13203.6 RUS87095.1 - 0.059 13.0 0.9 0.088 12.4 0.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 RUS87095.1 - 0.088 12.6 3.9 0.14 12.0 3.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.9 RUS87095.1 - 0.45 9.3 5.9 0.61 8.9 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein EF-hand_1 PF00036.32 RUS87097.1 - 2.9e-28 95.3 14.2 3e-07 29.5 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS87097.1 - 1.9e-25 89.1 6.0 9.8e-15 54.8 0.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS87097.1 - 3e-22 76.6 9.2 9e-06 25.2 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RUS87097.1 - 5e-21 73.2 10.5 2.7e-05 23.4 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RUS87097.1 - 7.8e-19 67.3 11.3 2.1e-05 24.2 0.3 4.4 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS87097.1 - 4.3e-08 33.5 0.3 0.00091 19.5 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS87097.1 - 3.4e-07 30.2 5.3 0.0023 17.8 0.3 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RUS87097.1 - 0.00051 20.3 0.3 0.084 13.2 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 RUS87097.1 - 0.03 14.3 3.1 7.1 6.5 0.0 3.4 2 2 2 4 4 4 0 Caleosin related protein SpaA PF17802.1 RUS87097.1 - 0.084 13.2 0.0 4.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Prealbumin-like fold domain Dockerin_1 PF00404.18 RUS87097.1 - 1.5 9.1 7.3 3.8 7.8 1.7 3.3 1 1 2 3 3 3 0 Dockerin type I domain JAMP PF05571.12 RUS87098.1 - 8.2e-109 363.7 16.5 8.2e-109 363.7 16.5 1.5 2 0 0 2 2 2 1 JNK1/MAPK8-associated membrane protein UTP25 PF06862.12 RUS87100.1 - 2e-162 541.3 7.9 2.6e-162 540.9 7.9 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyco_transf_7N PF13733.6 RUS87100.1 - 0.14 11.8 1.7 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 SDA1 PF05285.12 RUS87100.1 - 0.44 9.9 24.4 0.82 9.0 24.4 1.5 1 0 0 1 1 1 0 SDA1 zf-C4 PF00105.18 RUS87101.1 - 1.8e-43 146.9 35.9 8.2e-23 80.6 12.4 3.2 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS87101.1 - 1.1e-12 48.0 2.7 4.1e-12 46.1 2.7 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ras PF00071.22 RUS87102.1 - 3.4e-45 153.6 0.0 4.4e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS87102.1 - 5.9e-18 65.2 0.0 8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS87102.1 - 8.2e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pax7 PF12360.8 RUS87103.1 - 0.38 11.0 58.9 7.1 6.9 2.1 8.3 1 1 7 8 8 8 0 Paired box protein 7 PIP49_C PF12260.8 RUS87104.1 - 1.6e-31 109.5 0.0 2.6e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 RUS87104.1 - 0.00068 19.5 0.9 0.0016 18.3 0.9 1.6 1 1 0 1 1 1 1 N-term cysteine-rich ER, FAM69 NT-C2 PF10358.9 RUS87105.1 - 4.2e-26 91.4 0.1 9.6e-26 90.2 0.1 1.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Zona_pellucida PF00100.23 RUS87106.1 - 3.5e-25 89.3 0.6 9.8e-25 87.8 0.6 1.7 1 1 0 1 1 1 1 Zona pellucida-like domain DUF4307 PF14155.6 RUS87106.1 - 0.0061 16.4 0.3 0.024 14.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4307) DNA_pol_viral_N PF00242.17 RUS87106.1 - 0.018 14.6 0.1 0.018 14.6 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain MLANA PF14991.6 RUS87106.1 - 0.034 14.4 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein melan-A FAST_1 PF06743.15 RUS87107.1 - 9.4e-05 22.3 1.4 0.00071 19.5 0.0 3.1 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.12 RUS87107.1 - 0.097 13.5 0.4 0.78 10.6 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 Mating_N PF12731.7 RUS87108.1 - 0.036 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 NUC194 PF08163.12 RUS87108.1 - 0.19 10.6 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 NUC194 domain Arf PF00025.21 RUS87109.1 - 1.4e-76 255.8 0.0 1.6e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS87109.1 - 3.2e-15 56.4 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS87109.1 - 8.9e-15 54.7 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RUS87109.1 - 1.1e-12 47.8 0.9 3.4e-08 33.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RUS87109.1 - 1.9e-11 43.7 0.0 2.4e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RUS87109.1 - 6.5e-10 38.8 0.0 8.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS87109.1 - 0.00011 22.2 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RUS87109.1 - 0.039 13.3 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 RUS87109.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Arf PF00025.21 RUS87110.1 - 1.1e-59 200.9 0.0 1.2e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RUS87110.1 - 2.7e-11 43.3 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS87110.1 - 3.2e-11 43.5 0.0 4.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RUS87110.1 - 9.4e-09 34.9 0.1 1.9e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS87110.1 - 1.1e-07 31.4 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS87110.1 - 1.8e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS87110.1 - 0.05 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase CRISPR_Cas2 PF09827.9 RUS87110.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 PI3Ka PF00613.20 RUS87111.1 - 4.9e-60 202.1 0.2 9.1e-60 201.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RUS87111.1 - 1.2e-53 182.5 0.0 5.4e-53 180.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 RUS87111.1 - 2e-31 107.5 0.1 4.7e-31 106.3 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 RUS87111.1 - 1.6e-19 70.0 0.0 1.7e-17 63.5 0.1 3.3 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 RUS87111.1 - 4e-18 65.7 0.0 9.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 RUS87111.1 - 0.00087 19.6 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.6 RUS87111.1 - 0.0035 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF1837 PF08878.11 RUS87111.1 - 0.13 12.0 0.5 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) PLAT PF01477.23 RUS87112.1 - 1.7e-12 47.9 1.4 6.9e-12 46.0 1.4 1.9 1 1 0 1 1 1 1 PLAT/LH2 domain EzrA PF06160.12 RUS87113.1 - 0.0044 15.3 0.1 0.0044 15.3 0.1 3.3 3 1 1 4 4 4 1 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.8 RUS87113.1 - 0.0084 16.1 2.0 0.055 13.5 0.0 3.4 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 RUS87113.1 - 0.016 15.3 18.8 2.6 8.1 0.1 5.6 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.23 RUS87113.1 - 0.18 12.4 12.7 3.9 8.1 0.6 4.1 3 1 0 4 4 4 0 Hemerythrin HHE cation binding domain Mating_N PF12731.7 RUS87113.1 - 0.85 9.7 3.7 0.86 9.7 0.3 2.9 3 0 0 3 3 3 0 Mating-type protein beta 1 FliD_N PF02465.18 RUS87113.1 - 0.91 10.3 10.0 8.4 7.2 0.0 5.2 5 1 0 5 5 5 0 Flagellar hook-associated protein 2 N-terminus Apolipoprotein PF01442.18 RUS87113.1 - 2.7 7.8 40.2 5.8 6.7 0.0 5.5 3 2 1 4 4 4 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 RUS87113.1 - 3.4 7.8 17.9 40 4.4 0.1 4.6 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 RUS87113.1 - 3.7 8.0 20.8 0.31 11.4 0.8 5.3 4 1 2 6 6 6 0 Syntaxin-like protein ApoLp-III PF07464.11 RUS87113.1 - 4.7 7.3 20.5 0.94 9.6 2.6 5.2 4 2 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) APC_N_CC PF16689.5 RUS87113.1 - 6.9 6.8 6.6 50 4.1 0.1 3.7 4 0 0 4 4 3 0 Coiled-coil N-terminus of APC, dimerisation domain Prominin PF05478.11 RUS87113.1 - 9.8 4.0 9.1 9.3 4.1 5.3 2.5 2 1 2 4 4 4 0 Prominin Utp13 PF08625.11 RUS87114.1 - 8.6e-07 29.0 3.6 16 5.4 0.1 7.4 1 1 6 8 8 8 1 Utp13 specific WD40 associated domain DUF2715 PF10895.8 RUS87114.1 - 0.0059 16.3 0.7 12 5.5 0.7 5.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2715) DtxR PF18357.1 RUS87114.1 - 0.071 12.8 26.1 3.1e+02 1.1 0.0 12.7 15 0 0 15 15 15 0 Diphteria toxin repressor SH3 domain RNA_pol_L_2 PF13656.6 RUS87114.1 - 0.084 12.7 0.0 14 5.5 0.0 3.7 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5509 PF17625.2 RUS87114.1 - 0.14 11.2 4.2 54 2.8 0.0 4.8 1 1 7 8 8 8 0 Family of unknown function (DUF5509) DUF1412 PF07203.11 RUS87115.1 - 0.24 11.6 8.2 2.9e+02 1.8 0.0 6.3 7 1 1 8 8 8 0 Protein of unknown function (DUF1412) Perm-CXXC PF15629.6 RUS87115.1 - 0.28 11.5 33.6 18 5.7 0.1 8.6 8 2 1 9 9 9 0 Permuted single zf-CXXC unit HC2 PF07382.11 RUS87117.1 - 1.1e-27 97.3 9.7 8.4e-11 42.3 0.4 3.1 2 1 1 3 3 3 3 Histone H1-like nucleoprotein HC2 Keratin_B2_2 PF13885.6 RUS87117.1 - 3e-13 49.5 92.5 0.00043 20.2 15.7 7.0 3 1 3 6 6 6 5 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 RUS87117.1 - 5.8e-07 29.6 82.2 0.0094 16.0 43.4 4.4 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein HLH PF00010.26 RUS87118.1 - 1.9e-16 59.7 0.7 4.7e-16 58.5 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS87118.1 - 9.5e-09 35.3 0.1 2.1e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange TSP_1 PF00090.19 RUS87119.1 - 5.6e-11 42.5 25.7 9.5e-07 28.9 10.2 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain tRNA-synt_2d PF01409.20 RUS87119.1 - 0.059 12.9 0.4 0.13 11.7 0.2 1.6 1 1 1 2 2 2 0 tRNA synthetases class II core domain (F) PRR20 PF15708.5 RUS87119.1 - 0.28 11.0 3.8 0.58 10.0 3.8 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 PRKG1_interact PF15898.5 RUS87119.1 - 1.1 10.3 6.5 0.36 11.7 1.6 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 RUS87119.1 - 1.8 9.3 0.0 1.8 9.3 0.0 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Ribosomal_60s PF00428.19 RUS87119.1 - 5.2 7.7 13.0 0.13 12.9 6.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pinin_SDK_N PF04697.13 RUS87119.1 - 5.4 7.7 10.3 2.4 8.8 7.1 2.1 2 0 0 2 2 2 0 pinin/SDK conserved region Chorion_2 PF03964.15 RUS87119.1 - 8.5 7.3 13.3 0.72 10.7 5.8 3.0 4 0 0 4 4 4 0 Chorion family 2 SDA1 PF05285.12 RUS87120.1 - 0.00059 19.4 51.6 0.00075 19.0 51.6 1.2 1 0 0 1 1 1 1 SDA1 DUF515 PF04415.12 RUS87120.1 - 0.98 7.7 3.5 1.4 7.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CDC45 PF02724.14 RUS87120.1 - 2.9 6.1 59.4 1.8e+04 -7.6 59.4 2.0 1 1 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 RUS87121.1 - 0.45 10.5 9.8 0.045 13.7 1.9 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) S-l_SbsC_C PF18316.1 RUS87123.1 - 0.057 13.9 0.0 0.27 11.8 0.0 2.1 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain MBOAT PF03062.19 RUS87124.1 - 9.4e-46 156.7 5.8 4.5e-45 154.5 5.8 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HalX PF08663.10 RUS87125.1 - 8e-06 26.1 15.5 1.1 9.6 0.3 4.4 1 1 2 3 3 3 3 HalX domain DUF4573 PF15140.6 RUS87125.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) DUF536 PF04394.14 RUS87125.1 - 3.1 7.7 13.9 70 3.4 0.2 6.2 1 1 9 10 10 10 0 Protein of unknown function, DUF536 CIDE-N PF02017.15 RUS87125.1 - 6 7.0 33.1 1.6 8.8 1.4 5.7 1 1 6 7 7 7 0 CIDE-N domain Podovirus_Gp16 PF05894.12 RUS87125.1 - 6.5 6.1 15.2 1.7 8.0 1.3 3.1 1 1 2 3 3 3 0 Podovirus DNA encapsidation protein (Gp16) CARD PF00619.21 RUS87127.1 - 0.00014 21.8 0.1 0.00039 20.4 0.1 1.7 1 0 0 1 1 1 1 Caspase recruitment domain FAM76 PF16046.5 RUS87127.1 - 6.8 6.0 16.6 13 5.0 16.6 1.5 1 1 0 1 1 1 0 FAM76 protein Aminotran_5 PF00266.19 RUS87128.1 - 2.9e-39 135.1 0.0 3.8e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 RUS87128.1 - 0.0075 15.5 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 Aminotransferase class I and II Band_7 PF01145.25 RUS87129.1 - 1.3e-21 77.5 7.8 1.3e-21 77.5 7.8 2.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 RUS87129.1 - 0.01 15.9 2.2 0.021 15.0 2.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_12 PF13424.6 RUS87130.1 - 2.3e-14 53.5 2.8 1.1e-06 28.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RUS87130.1 - 1.1e-10 40.8 2.3 0.25 11.6 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS87130.1 - 3.1e-10 39.3 2.4 0.24 11.6 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat zf-MYND PF01753.18 RUS87130.1 - 2.2e-08 34.1 4.8 4.7e-08 33.0 4.8 1.6 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.28 RUS87130.1 - 4.7e-07 29.4 2.5 0.14 12.0 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 RUS87130.1 - 4.7e-07 29.5 0.8 0.9 9.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS87130.1 - 2.8e-06 26.9 0.1 0.00043 19.8 0.0 2.3 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 RUS87130.1 - 2e-05 24.3 1.8 0.13 12.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS87130.1 - 0.0016 19.0 2.7 0.73 10.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 RUS87130.1 - 0.0036 17.0 0.9 1.1 8.9 0.0 2.6 2 1 1 3 3 3 2 26S proteasome subunit RPN7 zf-Mss51 PF13824.6 RUS87130.1 - 0.016 15.3 4.0 0.1 12.7 4.3 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_16 PF13432.6 RUS87130.1 - 0.19 12.4 2.2 48 4.7 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-HIT PF04438.16 RUS87130.1 - 0.47 10.4 4.7 0.93 9.4 4.7 1.4 1 0 0 1 1 1 0 HIT zinc finger Fzo_mitofusin PF04799.13 RUS87131.1 - 1.3e-56 190.6 2.9 1.3e-56 190.6 2.9 3.6 4 1 0 4 4 4 1 fzo-like conserved region Dynamin_N PF00350.23 RUS87131.1 - 1.7e-22 80.3 3.8 6.1e-22 78.5 0.0 3.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 RUS87131.1 - 1.6e-07 31.4 0.0 2.1e-06 27.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase PhaP_Bmeg PF09602.10 RUS87131.1 - 0.0011 18.9 3.6 0.0011 18.9 3.6 3.2 4 0 0 4 4 4 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RsgA_GTPase PF03193.16 RUS87131.1 - 0.095 12.6 0.9 0.83 9.5 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 RUS87131.1 - 0.11 13.1 2.8 4.1 7.9 2.7 3.1 1 1 0 1 1 1 0 ABC transporter Lar_N PF09861.9 RUS87131.1 - 0.44 9.7 3.6 13 4.9 0.7 2.8 3 0 0 3 3 3 0 Lactate racemase N-terminal domain DUF1664 PF07889.12 RUS87131.1 - 0.97 9.5 18.5 0.88 9.6 3.5 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) STAG PF08514.11 RUS87131.1 - 3.1 7.7 9.5 0.32 10.9 0.7 3.2 3 0 0 3 3 3 0 STAG domain DUF948 PF06103.11 RUS87131.1 - 4.5 7.6 11.8 9.2 6.6 0.0 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) WAP PF00095.21 RUS87132.1 - 6.2e-07 29.7 13.1 6.2e-07 29.7 13.1 2.6 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' YEATS PF03366.16 RUS87133.1 - 4.6e-34 116.2 0.7 8.5e-34 115.4 0.7 1.4 1 0 0 1 1 1 1 YEATS family DUF4763 PF15960.5 RUS87133.1 - 0.0018 17.6 0.5 0.0026 17.1 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) DUF812 PF05667.11 RUS87133.1 - 0.0037 16.2 1.0 0.0052 15.7 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Fusion_gly PF00523.18 RUS87133.1 - 0.014 13.6 1.1 0.15 10.3 0.9 2.1 1 1 0 2 2 2 0 Fusion glycoprotein F0 Tektin PF03148.14 RUS87133.1 - 0.023 13.5 1.8 0.032 13.0 1.8 1.1 1 0 0 1 1 1 0 Tektin family DUF1664 PF07889.12 RUS87133.1 - 0.035 14.2 1.4 0.055 13.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 RUS87133.1 - 0.04 13.0 0.3 0.049 12.7 0.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Dad1 PF08649.10 RUS87133.1 - 0.15 12.3 0.9 0.29 11.3 0.4 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad1 BRE1 PF08647.11 RUS87133.1 - 0.66 10.1 7.0 1.3 9.2 7.0 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4094 PF13334.6 RUS87133.1 - 1.1 9.7 3.5 2.4 8.6 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DDOST_48kD PF03345.14 RUS87134.1 - 1.2e-150 502.0 0.0 1.4e-150 501.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 RUS87134.1 - 0.011 14.1 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Sec1 PF00995.23 RUS87136.1 - 8e-13 48.5 0.0 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Sec1 family MSC PF09402.10 RUS87137.1 - 1.2e-13 51.2 0.4 3.2e-13 49.9 0.1 1.7 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain LEM PF03020.15 RUS87137.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 LEM domain RVT_1 PF00078.27 RUS87138.1 - 3.3e-11 43.1 0.0 5.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS87138.1 - 0.0016 18.2 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS87138.1 - 0.04 13.4 0.0 0.25 10.8 0.0 2.1 2 1 1 3 3 3 0 Endonuclease/Exonuclease/phosphatase family SLS PF14611.6 RUS87138.1 - 0.074 12.9 1.9 0.15 11.9 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator YrhC PF14143.6 RUS87138.1 - 0.095 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 YrhC-like protein Peptidase_A17 PF05380.13 RUS87139.1 - 7.3e-54 182.1 0.2 1.5e-53 181.1 0.2 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 RUS87139.1 - 4.1e-22 78.2 0.0 1.4e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5641) RVT_1 PF00078.27 RUS87139.1 - 2.6e-07 30.4 0.1 6.3e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS87139.1 - 9.6e-07 28.8 3.6 2.8e-06 27.3 3.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS87139.1 - 3.4e-06 27.3 0.0 8.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS87139.1 - 0.022 15.0 1.3 0.059 13.6 1.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger BBIP10 PF14777.6 RUS87139.1 - 0.074 12.6 0.6 0.22 11.1 0.6 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Flavokinase PF01687.17 RUS87140.1 - 1.2e-30 106.1 0.0 1.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DUF2464 PF10240.9 RUS87141.1 - 0.48 9.9 7.7 0.52 9.8 7.7 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Presenilin PF01080.17 RUS87141.1 - 2.5 6.8 10.5 3.1 6.5 10.5 1.0 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 RUS87141.1 - 5.1 7.5 16.0 7.1 7.0 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CobT PF06213.12 RUS87141.1 - 8.4 5.7 5.5 9.4 5.5 5.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4071 PF13281.6 RUS87143.1 - 4.9e-149 496.4 0.1 6.9e-149 495.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 RUS87143.1 - 8.2e-65 218.8 0.0 1.5e-64 217.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87143.1 - 2.7e-44 151.4 0.0 4.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS87143.1 - 0.0043 15.9 0.0 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RUS87143.1 - 0.018 14.3 0.0 0.085 12.2 0.0 2.0 2 1 1 3 3 3 0 Kinase-like IL17R_fnIII_D2 PF16578.5 RUS87144.1 - 0.013 16.0 1.9 3.3 8.3 0.3 2.6 1 1 3 4 4 4 0 Interleukin 17 receptor D FTO_NTD PF12933.7 RUS87144.1 - 0.021 14.1 1.2 37 3.4 0.0 3.6 1 1 3 4 4 4 0 FTO catalytic domain Erg28 PF03694.13 RUS87144.1 - 0.034 14.5 4.3 13 6.3 0.1 3.3 1 1 3 4 4 4 0 Erg28 like protein oligo_HPY PF08352.12 RUS87144.1 - 0.14 12.7 20.7 51 4.5 0.1 7.1 1 1 7 8 8 8 0 Oligopeptide/dipeptide transporter, C-terminal region BMF PF15185.6 RUS87144.1 - 0.52 10.0 2.7 31 4.2 0.1 2.8 1 1 4 5 5 5 0 Bcl-2-modifying factor, apoptosis KNOX2 PF03791.13 RUS87144.1 - 4.8 6.8 6.0 2.1e+02 1.5 0.0 4.4 6 0 0 6 6 6 0 KNOX2 domain LrgB PF04172.16 RUS87145.1 - 3.3e-05 23.5 10.8 0.44 10.0 1.2 4.7 1 1 3 4 4 4 4 LrgB-like family Glyco_hydro_30C PF17189.4 RUS87145.1 - 0.016 15.4 10.7 22 5.4 2.3 5.2 1 1 2 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain Bmp PF02608.14 RUS87145.1 - 0.15 11.0 2.8 4.4 6.2 0.3 2.4 1 1 2 3 3 3 0 ABC transporter substrate-binding protein PnrA-like YhcG_C PF06250.11 RUS87146.1 - 1.4 8.7 8.3 60 3.4 0.2 3.3 1 1 3 4 4 4 0 YhcG PDDEXK nuclease domain zf-Sec23_Sec24 PF04810.15 RUS87147.1 - 9.6e-08 32.0 1.9 0.6 10.2 0.0 3.3 3 0 0 3 3 3 3 Sec23/Sec24 zinc finger FerB PF08150.12 RUS87147.1 - 0.00011 22.7 0.3 8.2 7.1 0.0 3.7 1 1 2 4 4 4 3 FerB (NUC096) domain zf-C3Hc3H PF13891.6 RUS87147.1 - 0.00013 22.3 0.5 46 4.5 0.1 4.3 4 0 0 4 4 4 0 Potential DNA-binding domain Na_trans_cytopl PF11933.8 RUS87147.1 - 0.00028 20.8 0.4 6.2 6.6 0.0 3.1 3 0 0 3 3 3 2 Cytoplasmic domain of voltage-gated Na+ ion channel DUF1627 PF07789.12 RUS87147.1 - 0.015 14.9 0.0 21 4.7 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1627) EutB PF06751.11 RUS87147.1 - 0.035 12.9 0.0 28 3.3 0.0 2.9 2 1 1 3 3 3 0 Ethanolamine ammonia lyase large subunit (EutB) GIY-YIG PF01541.24 RUS87147.1 - 0.079 13.2 5.0 22 5.4 0.4 3.3 3 1 0 3 3 3 0 GIY-YIG catalytic domain DUF3970 PF13113.6 RUS87147.1 - 0.084 13.1 1.1 29 5.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3970) Csc2 PF18320.1 RUS87147.1 - 0.18 10.7 0.0 58 2.5 0.0 2.9 3 0 0 3 3 3 0 Csc2 Crispr IMS_C PF11799.8 RUS87147.1 - 1.3 9.8 7.4 62 4.3 3.1 3.1 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain DUF3224 PF11528.8 RUS87148.1 - 0.023 14.5 0.0 36 4.2 0.0 3.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3224) Methyltransf_25 PF13649.6 RUS87148.1 - 0.72 10.6 3.3 1.1e+02 3.6 3.3 3.2 1 1 0 1 1 1 0 Methyltransferase domain Thioredoxin_12 PF18400.1 RUS87148.1 - 2.5 7.9 11.2 22 4.8 1.1 3.3 1 1 1 2 2 2 0 Thioredoxin-like domain Colipase-like PF15083.6 RUS87149.1 - 0.0045 17.1 7.6 0.0095 16.0 7.7 1.5 1 1 0 1 1 1 1 Colipase-like FYVE_2 PF02318.16 RUS87150.1 - 3.6e-07 30.4 2.1 3.6e-07 30.4 2.1 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger Reprolysin_5 PF13688.6 RUS87151.1 - 1.1e-13 51.8 1.2 4.7e-13 49.7 0.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin PF01421.19 RUS87151.1 - 8.4e-12 45.4 0.1 2.1e-11 44.1 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.6 RUS87151.1 - 1.4e-09 38.1 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS87151.1 - 1.6e-07 31.2 0.1 2.4e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 RUS87151.1 - 1.8e-07 31.7 1.0 3.8e-07 30.7 0.0 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 RUS87151.1 - 3.7e-05 24.1 2.8 0.00019 21.9 1.2 2.4 2 0 0 2 2 2 1 ADAM cysteine-rich domain RR_TM4-6 PF06459.12 RUS87151.1 - 7.6e-05 22.7 18.3 0.00011 22.2 18.3 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RUS87151.1 - 0.00014 22.1 3.2 0.00022 21.4 3.2 1.3 1 0 0 1 1 1 1 DDHD domain NPR3 PF03666.13 RUS87151.1 - 0.00019 20.4 17.8 0.00027 19.9 17.8 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 RUS87151.1 - 0.00059 19.0 2.7 0.00089 18.4 2.7 1.2 1 0 0 1 1 1 1 CLN3 protein NARP1 PF12569.8 RUS87151.1 - 0.00077 18.5 27.2 0.0012 17.9 27.2 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Radial_spoke PF04712.12 RUS87151.1 - 0.002 17.2 9.3 0.0029 16.6 9.3 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein Peptidase_M43 PF05572.13 RUS87151.1 - 0.002 18.0 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A DUF5308 PF17233.2 RUS87151.1 - 0.0023 18.2 1.7 0.0041 17.4 1.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5308) DUF4228 PF14009.6 RUS87151.1 - 0.0026 18.2 6.6 0.0026 18.2 6.6 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4228) AAA_11 PF13086.6 RUS87151.1 - 0.0064 16.3 14.1 0.011 15.6 14.1 1.3 1 0 0 1 1 1 1 AAA domain DUF2151 PF10221.9 RUS87151.1 - 0.011 14.4 14.7 0.015 14.0 14.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3984 PF13136.6 RUS87151.1 - 0.012 15.0 7.1 0.024 14.1 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PPL5 PF18168.1 RUS87151.1 - 0.019 14.3 14.8 0.032 13.5 14.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 RUS87151.1 - 0.021 15.3 20.6 0.04 14.4 20.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_M66 PF10462.9 RUS87151.1 - 0.021 13.8 3.6 0.044 12.7 3.6 1.6 1 1 0 1 1 1 0 Peptidase M66 SRP-alpha_N PF04086.13 RUS87151.1 - 0.023 14.6 28.0 0.065 13.2 28.0 1.7 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF262 PF03235.14 RUS87151.1 - 0.03 14.5 8.6 0.049 13.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF2828 PF11443.8 RUS87151.1 - 0.031 12.4 23.2 0.045 11.9 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TraH PF06122.11 RUS87151.1 - 0.041 13.2 9.0 0.062 12.6 9.0 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Afi1 PF07792.12 RUS87151.1 - 0.062 13.8 13.1 0.13 12.7 13.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LicD PF04991.13 RUS87151.1 - 0.084 13.0 26.9 0.14 12.3 26.9 1.3 1 0 0 1 1 1 0 LicD family Zip PF02535.22 RUS87151.1 - 0.1 11.8 10.3 0.15 11.2 10.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FGF-BP1 PF06473.12 RUS87151.1 - 0.1 12.4 28.6 0.23 11.3 28.6 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Dsh_C PF12316.8 RUS87151.1 - 0.17 12.3 1.1 0.31 11.4 1.1 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF913 PF06025.12 RUS87151.1 - 0.17 10.8 7.8 0.25 10.3 7.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 RUS87151.1 - 0.17 10.9 19.8 0.25 10.3 19.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 RUS87151.1 - 0.17 12.0 20.8 0.7 10.0 21.3 1.7 2 0 0 2 2 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 RUS87151.1 - 0.2 11.4 10.0 0.35 10.6 10.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2052 PF09747.9 RUS87151.1 - 0.23 11.6 14.5 0.4 10.8 14.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CENP-N PF05238.13 RUS87151.1 - 0.35 10.1 15.1 0.64 9.3 15.1 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Tim54 PF11711.8 RUS87151.1 - 0.49 9.1 24.4 0.77 8.5 24.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YL1 PF05764.13 RUS87151.1 - 0.5 10.4 37.8 1.1 9.3 37.8 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.17 RUS87151.1 - 0.74 8.5 16.1 1.1 7.9 16.1 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 RUS87151.1 - 0.77 10.1 42.1 1.4 9.2 42.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mitofilin PF09731.9 RUS87151.1 - 1.4 7.7 27.3 2 7.1 27.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DAG_kinase_N PF14513.6 RUS87151.1 - 1.6 8.9 20.7 3 8.0 20.7 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Connexin PF00029.19 RUS87151.1 - 1.7 8.3 23.8 3.1 7.5 23.8 1.3 1 0 0 1 1 1 0 Connexin CNDH2_M PF16869.5 RUS87151.1 - 1.8 9.3 8.2 3.9 8.2 8.2 1.5 1 0 0 1 1 1 0 PF16858 DUF4614 PF15391.6 RUS87151.1 - 2 8.4 12.3 3.4 7.6 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SID-1_RNA_chan PF13965.6 RUS87151.1 - 2.2 6.6 6.8 3.8 5.8 6.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hydin_ADK PF17213.3 RUS87151.1 - 2.5 8.4 7.5 5.9 7.1 7.5 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RP-C_C PF11800.8 RUS87151.1 - 2.5 8.1 7.7 4.5 7.3 7.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4407 PF14362.6 RUS87151.1 - 3.2 7.0 6.4 4.8 6.4 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Otopetrin PF03189.13 RUS87151.1 - 3.3 6.4 8.3 4.9 5.9 8.3 1.1 1 0 0 1 1 1 0 Otopetrin DUF5427 PF10310.9 RUS87151.1 - 4.1 6.3 24.4 6.1 5.7 24.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GCD14 PF08704.10 RUS87151.1 - 5.2 6.7 10.7 10 5.7 10.7 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RPOL_N PF14700.6 RUS87151.1 - 5.4 6.3 25.9 8.6 5.6 25.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Metallopep PF12044.8 RUS87151.1 - 7.1 5.1 12.4 17 3.9 12.4 1.6 1 1 0 1 1 1 0 Putative peptidase family CSG2 PF16965.5 RUS87151.1 - 7.6 5.4 9.5 11 4.9 9.5 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Paramyxo_ncap PF00973.19 RUS87151.1 - 7.6 5.3 16.6 11 4.8 16.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SpoIIP PF07454.11 RUS87151.1 - 7.9 5.8 26.3 14 5.0 26.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Bac_DnaA_C PF08299.11 RUS87152.1 - 0.01 15.8 2.6 3.7 7.7 0.0 3.1 2 1 1 3 3 3 0 Bacterial dnaA protein helix-turn-helix Romo1 PF10247.9 RUS87152.1 - 0.034 14.5 1.8 5.5 7.4 0.0 3.2 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Herpes_UL56 PF04534.12 RUS87152.1 - 1.3 8.5 10.8 0.048 13.1 1.5 2.2 2 0 0 2 2 2 0 Herpesvirus UL56 protein Ndufs5 PF10200.9 RUS87153.1 - 0.02 15.1 0.1 3.7 7.9 0.0 3.2 2 1 2 4 4 4 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Peptidase_C36 PF05415.11 RUS87153.1 - 0.045 14.0 1.0 0.26 11.5 0.2 2.2 1 1 1 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Helicase_Sgs1 PF11408.8 RUS87153.1 - 0.35 10.9 1.4 3.9 7.6 0.3 2.4 1 1 1 2 2 2 0 Sgs1 RecQ helicase YueH PF14166.6 RUS87153.1 - 0.44 10.4 4.8 9.9 6.1 0.5 3.7 1 1 3 4 4 4 0 YueH-like protein Amnionless PF14828.6 RUS87153.1 - 1.4 7.7 5.3 1.9 7.2 5.3 1.2 1 0 0 1 1 1 0 Amnionless VWA PF00092.28 RUS87154.1 - 1.7e-40 139.2 0.2 2e-40 138.9 0.2 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS87154.1 - 2.8e-12 47.2 0.0 5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS87154.1 - 0.027 14.4 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain NOA36 PF06524.12 RUS87158.1 - 2.1e-05 24.0 19.1 3.6e-05 23.2 19.1 1.3 1 0 0 1 1 1 1 NOA36 protein Sigma70_ner PF04546.13 RUS87158.1 - 0.0038 17.1 11.2 0.005 16.7 11.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.12 RUS87158.1 - 0.0062 14.8 13.5 0.0064 14.8 13.5 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 RUS87158.1 - 0.017 14.5 10.0 0.021 14.2 10.0 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 RUS87158.1 - 0.018 15.3 20.2 0.028 14.7 20.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 RUS87158.1 - 0.031 12.4 27.6 0.038 12.1 27.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 RUS87158.1 - 0.062 12.9 12.9 0.077 12.6 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 RUS87158.1 - 0.26 11.0 34.4 1.7 8.3 34.4 2.0 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Afi1 PF07792.12 RUS87158.1 - 0.58 10.6 10.4 1 9.8 10.5 1.4 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nucleo_P87 PF07267.11 RUS87158.1 - 1.3 7.8 7.3 1.4 7.7 7.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 RUS87158.1 - 3.6 7.5 20.7 5 7.0 20.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.6 RUS87160.1 - 5.5e-18 64.1 69.5 0.0076 17.0 2.6 9.7 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS87160.1 - 3.7e-14 52.3 70.4 0.00047 20.5 0.8 9.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS87160.1 - 2.9e-09 36.9 68.6 8.6e-05 22.8 0.3 10.3 10 0 0 10 10 9 4 Zinc-finger double domain zf-met PF12874.7 RUS87160.1 - 3.9e-05 23.9 49.4 0.033 14.6 1.6 8.7 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS87160.1 - 0.0012 18.8 8.8 0.0038 17.2 3.7 9.2 10 0 0 10 10 9 4 C2H2-type zinc finger SUIM_assoc PF16619.5 RUS87160.1 - 0.18 11.9 6.8 0.037 14.1 1.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_11 PF16622.5 RUS87160.1 - 0.35 10.7 15.9 0.093 12.5 0.7 4.4 3 0 0 3 3 3 0 zinc-finger C2H2-type Pes-10 PF07149.11 RUS87160.1 - 0.4 9.7 5.4 0.66 9.0 5.4 1.2 1 0 0 1 1 1 0 Pes-10 zf-C2H2_jaz PF12171.8 RUS87160.1 - 2.2 8.7 54.2 3.4 8.1 1.2 10.1 10 0 0 10 10 9 0 Zinc-finger double-stranded RNA-binding CDC45 PF02724.14 RUS87160.1 - 3.9 5.7 11.1 0.23 9.7 3.2 2.2 2 0 0 2 2 2 0 CDC45-like protein zf-FCS PF06467.14 RUS87160.1 - 8.8 6.4 25.2 1.4 9.0 0.5 6.4 7 0 0 7 7 7 0 MYM-type Zinc finger with FCS sequence motif 7tm_1 PF00001.21 RUS87161.1 - 0.0002 20.8 12.7 0.00027 20.3 12.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87161.1 - 0.004 16.8 17.1 0.004 16.8 17.1 2.0 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS87161.1 - 2.9 7.2 21.5 0.021 14.2 5.3 3.3 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx Ig_3 PF13927.6 RUS87162.1 - 1.5e-52 176.1 2.7 4.3e-14 52.9 0.2 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS87162.1 - 1e-42 144.1 0.0 8.1e-14 51.5 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS87162.1 - 3.3e-30 104.2 2.8 2.7e-07 30.8 0.1 4.4 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS87162.1 - 1.6e-25 89.0 0.1 1.8e-08 34.4 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 RUS87162.1 - 2.5e-22 79.1 5.4 0.00029 21.0 0.0 6.7 4 4 1 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS87162.1 - 7.1e-08 32.4 1.1 0.031 14.4 0.2 4.2 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS87162.1 - 0.0056 16.7 0.0 1.9 8.6 0.0 3.3 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 RUS87162.1 - 0.0094 15.5 0.1 7.4 6.2 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_5 PF16681.5 RUS87162.1 - 0.017 15.5 0.2 0.92 10.0 0.0 2.8 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 RUS87162.1 - 0.052 13.7 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 IMPa_N_2 PF18650.1 RUS87162.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain C1-set PF07654.15 RUS87162.1 - 0.19 12.2 0.4 10 6.6 0.0 3.6 5 0 0 5 5 5 0 Immunoglobulin C1-set domain adh_short PF00106.25 RUS87164.1 - 1.3e-19 70.4 0.4 4.9e-10 39.2 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RUS87164.1 - 3.3e-11 43.2 0.1 1.5e-07 31.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS87164.1 - 0.00013 21.9 0.6 0.021 14.7 0.0 2.1 1 1 1 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 RUS87164.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sds3 PF08598.11 RUS87167.1 - 3.7e-16 59.8 5.6 5.1e-16 59.3 5.6 1.3 1 0 0 1 1 1 1 Sds3-like TPD PF14811.6 RUS87167.1 - 0.01 15.7 0.7 0.019 14.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF3850 PF12961.7 RUS87167.1 - 0.13 12.3 0.6 0.3 11.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) DUF2746 PF10874.8 RUS87167.1 - 0.19 12.2 1.4 0.69 10.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) DDE_Tnp_4 PF13359.6 RUS87168.1 - 5.2e-26 91.2 0.0 1.1e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS87168.1 - 0.00014 21.6 0.0 0.0013 18.4 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein Tektin PF03148.14 RUS87169.1 - 1.1e-150 501.7 34.9 1.2e-150 501.6 34.9 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.12 RUS87169.1 - 0.06 13.4 0.6 0.06 13.4 0.6 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 RUS87169.1 - 0.08 12.5 22.3 0.036 13.6 8.1 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit TPK_catalytic PF04263.16 RUS87169.1 - 0.1 12.6 3.4 6 6.9 0.3 2.4 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Baculo_PEP_C PF04513.12 RUS87169.1 - 0.32 11.0 13.8 5.9 6.9 0.5 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4359 PF14271.6 RUS87169.1 - 0.83 10.4 6.1 2.1 9.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4359) MitMem_reg PF13012.6 RUS87169.1 - 3 8.3 7.6 21 5.6 3.2 3.5 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function ApoLp-III PF07464.11 RUS87169.1 - 3 7.9 23.9 2.8 8.0 1.3 4.2 3 3 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 RUS87169.1 - 3.6 7.1 33.8 0.032 13.8 10.4 2.5 2 1 0 2 2 2 0 Intermediate filament protein Phasin PF05597.11 RUS87169.1 - 8.2 6.4 14.7 0.17 11.9 2.1 3.5 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AMP-binding PF00501.28 RUS87170.1 - 3.1e-43 147.9 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 RUS87170.1 - 3.4e-09 36.5 1.8 6.2e-09 35.6 1.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus HSP20 PF00011.21 RUS87171.1 - 1.9e-17 63.3 0.1 2.8e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RUS87171.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF3045 PF11243.8 RUS87171.1 - 0.049 13.8 0.1 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) RRM_1 PF00076.22 RUS87172.1 - 1.2e-11 44.3 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A_type_inc PF04508.12 RUS87173.1 - 0.17 11.8 0.1 0.17 11.8 0.1 6.3 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 RUS87173.1 - 3.5 7.8 134.7 0.14 12.4 29.9 6.9 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) DUF4347 PF14252.6 RUS87176.1 - 0.23 11.3 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) DUF4455 PF14643.6 RUS87181.1 - 4.7e-38 131.0 5.8 6.5e-38 130.6 5.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) PCRF PF03462.18 RUS87181.1 - 0.65 9.8 4.0 0.49 10.2 1.4 2.0 2 1 1 3 3 3 0 PCRF domain DUF4455 PF14643.6 RUS87182.1 - 1.3e-90 304.3 6.8 1.3e-90 304.3 6.8 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 RUS87182.1 - 2.2e-27 96.2 4.4 2.2e-27 96.2 4.4 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4456) CLZ PF16526.5 RUS87182.1 - 0.028 14.8 0.2 0.028 14.8 0.2 7.0 8 0 0 8 8 8 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 RUS87182.1 - 3.2 8.1 21.4 0.38 11.1 0.1 4.4 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) Mt_ATP-synt_D PF05873.12 RUS87182.1 - 4.7 7.1 5.4 7.7 6.4 0.2 3.6 4 0 0 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Lectin_N PF03954.14 RUS87182.1 - 6.9 6.4 20.2 6 6.6 0.1 5.4 4 1 1 5 5 5 0 Hepatic lectin, N-terminal domain DUF2935 PF11155.8 RUS87182.1 - 8.4 6.7 16.5 2.9 8.2 1.8 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF2935) Sensor_TM1 PF13755.6 RUS87183.1 - 0.0047 16.6 13.0 33 4.3 0.0 6.1 1 1 6 7 7 7 2 Sensor N-terminal transmembrane domain Pox_I3 PF04661.12 RUS87183.1 - 0.01 15.0 0.0 4.7 6.3 0.0 2.9 1 1 2 3 3 3 3 Poxvirus I3 ssDNA-binding protein Opacity PF02462.15 RUS87183.1 - 0.034 14.2 0.6 54 3.9 0.0 3.2 1 1 2 3 3 3 0 Opacity family porin protein PAD PF03068.15 RUS87183.1 - 0.049 12.6 0.6 29 3.5 0.0 3.0 1 1 1 3 3 3 0 Protein-arginine deiminase (PAD) DUF3413 PF11893.8 RUS87183.1 - 0.16 11.1 1.1 2.4 7.3 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) Arrestin_C PF02752.22 RUS87184.1 - 2.4e-08 34.5 0.0 3.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain STAG PF08514.11 RUS87185.1 - 0.034 14.1 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 STAG domain DUF4456 PF14644.6 RUS87186.1 - 0.0076 16.0 1.0 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) TED_complement PF07678.14 RUS87187.1 - 4.4e-98 328.2 0.1 6.2e-98 327.7 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 RUS87187.1 - 5.8e-27 94.2 0.4 2.8e-26 92.0 0.1 2.4 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain A2M PF00207.22 RUS87187.1 - 3.8e-26 90.8 0.0 1.1e-25 89.3 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 RUS87187.1 - 1.4e-18 67.5 0.1 2.3e-16 60.4 0.0 3.8 2 2 1 3 3 3 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 RUS87187.1 - 6e-15 55.3 0.1 2.2e-14 53.5 0.1 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 RUS87187.1 - 1.9e-14 53.9 0.0 1.6e-13 50.9 0.0 2.7 2 0 0 2 2 2 1 MG2 domain MG4 PF17789.1 RUS87187.1 - 6.4e-08 32.6 0.0 5.2e-07 29.7 0.0 2.6 2 0 0 2 2 2 1 Macroglobulin domain MG4 NTR PF01759.21 RUS87187.1 - 7.3e-06 25.7 0.0 2.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ribosomal_L28e PF01778.17 RUS87190.1 - 1.4e-27 96.7 1.6 2.2e-27 96.1 1.6 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF5513 PF17632.2 RUS87190.1 - 0.053 13.9 0.1 0.98 9.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5513) PABP PF00658.18 RUS87192.1 - 2.1e-32 111.1 0.0 4.9e-12 45.9 0.0 3.2 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain HTH_9 PF08221.11 RUS87192.1 - 0.011 15.8 0.2 0.57 10.3 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glucosamine_iso PF01182.20 RUS87194.1 - 1.4e-70 237.7 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Snapin_Pallidin PF14712.6 RUS87195.1 - 1.1e-26 93.1 0.2 1.4e-26 92.8 0.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Eisosome1 PF12757.7 RUS87195.1 - 0.00054 20.2 0.9 0.0043 17.3 0.1 2.0 2 0 0 2 2 2 1 Eisosome protein 1 XhlA PF10779.9 RUS87195.1 - 0.00073 19.7 1.6 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 Haemolysin XhlA Laminin_II PF06009.12 RUS87195.1 - 0.0072 16.3 0.6 0.01 15.9 0.6 1.2 1 0 0 1 1 1 1 Laminin Domain II NPV_P10 PF05531.12 RUS87195.1 - 0.065 13.7 1.0 0.41 11.2 1.0 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 RUS87195.1 - 0.065 12.1 0.2 0.084 11.7 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.6 RUS87195.1 - 0.066 13.5 0.6 0.11 12.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 RUS87195.1 - 0.071 13.5 1.4 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 RUS87195.1 - 0.13 12.8 1.1 0.21 12.1 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 NPDC1 PF06809.11 RUS87196.1 - 9.2e-35 120.3 0.2 1.2e-34 119.9 0.2 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Pex14_N PF04695.13 RUS87196.1 - 0.00098 19.8 0.7 0.00098 19.8 0.7 2.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EBV-NA3 PF05009.12 RUS87196.1 - 0.064 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CbtA PF09490.10 RUS87196.1 - 0.46 10.2 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) IRS PF02174.17 RUS87197.1 - 1e-16 60.7 0.0 2.2e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) zf-met PF12874.7 RUS87198.1 - 9.8e-08 32.1 16.3 7.5e-06 26.2 0.6 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS87198.1 - 2.5e-06 27.6 16.6 0.00019 21.6 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RUS87198.1 - 0.035 13.9 20.3 0.048 13.4 0.8 4.4 4 0 0 4 4 4 0 U1 zinc finger zf-C2H2_2 PF12756.7 RUS87198.1 - 0.14 12.6 14.1 6.6 7.1 0.6 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 RUS87198.1 - 3.6 7.8 13.7 5.8 7.1 4.6 3.1 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) TauD PF02668.16 RUS87199.1 - 3.5e-05 23.7 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 RUS87200.1 - 1.2e-14 54.8 0.0 1.4e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PBC PF03792.13 RUS87201.1 - 1.5e-91 305.3 1.0 2.2e-91 304.8 1.0 1.3 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 RUS87201.1 - 1.8e-19 69.4 1.0 4.5e-19 68.0 0.5 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS87201.1 - 3.2e-16 58.9 0.0 1.9e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 RUS87201.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 RUS87201.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.12 RUS87201.1 - 0.025 14.0 0.3 0.041 13.3 0.3 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HTH_26 PF13443.6 RUS87201.1 - 0.025 15.0 0.0 0.15 12.5 0.0 2.2 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 RUS87201.1 - 0.055 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain NUC130_3NT PF08158.12 RUS87201.1 - 0.25 11.7 0.7 38 4.7 0.0 2.9 3 0 0 3 3 3 0 NUC130/3NT domain HTH_19 PF12844.7 RUS87201.1 - 0.3 11.2 1.2 6.1 6.9 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain CX9C PF16860.5 RUS87202.1 - 9.1e-16 57.6 9.5 2.1e-09 37.3 1.4 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 RUS87202.1 - 7.9e-06 25.9 11.5 0.0012 18.9 4.6 3.2 3 0 0 3 3 3 2 CHCH domain NDUF_B7 PF05676.13 RUS87202.1 - 0.0024 17.6 9.6 0.11 12.2 1.0 2.3 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RUS87202.1 - 0.011 15.8 11.8 0.016 15.2 1.8 3.0 1 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 RUS87202.1 - 0.027 14.7 7.2 8.8 6.7 0.0 3.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) MTCP1 PF08991.10 RUS87202.1 - 0.084 13.1 5.6 0.11 12.8 0.5 2.4 2 1 0 2 2 2 0 Mature-T-Cell Proliferation I type GCK PF07802.11 RUS87202.1 - 0.5 10.8 8.5 10 6.6 0.1 2.9 1 1 1 2 2 2 0 GCK domain Pet191_N PF10203.9 RUS87202.1 - 0.62 10.4 11.1 10 6.5 2.4 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 RUS87202.1 - 2.1 8.8 8.6 1.2 9.5 1.6 2.7 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) CD225 PF04505.12 RUS87205.1 - 2.5e-08 33.9 3.1 4.1e-08 33.2 3.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein UL45 PF05473.12 RUS87205.1 - 0.071 12.7 2.6 1.3 8.7 2.6 2.0 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like SRA1 PF07304.11 RUS87205.1 - 0.14 11.9 0.4 0.18 11.6 0.4 1.3 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) CAP_N PF01213.19 RUS87205.1 - 5.7 6.3 9.0 7 6.0 9.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltrn_RNA_3 PF02598.17 RUS87206.1 - 7.7e-105 350.5 0.0 1e-104 350.1 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 RUS87206.1 - 0.054 13.7 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 SpoU rRNA Methylase family DUF4483 PF14825.6 RUS87206.1 - 0.073 12.8 4.3 0.12 12.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Spc7_N PF15402.6 RUS87206.1 - 0.76 8.0 5.8 1.1 7.4 5.8 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Tfb2 PF03849.14 RUS87207.1 - 3.9e-102 341.9 0.1 1.1e-88 297.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor Tfb2 Tfb2_C PF18307.1 RUS87207.1 - 4e-26 91.2 0.8 4e-26 91.2 0.8 1.9 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RUS87207.1 - 0.0027 17.8 0.0 0.008 16.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain F-box-like PF12937.7 RUS87208.1 - 8.7e-16 57.6 4.9 1.9e-15 56.4 4.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS87208.1 - 3.3e-11 42.8 2.3 8.6e-11 41.4 2.3 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 RUS87208.1 - 3.1e-10 40.5 13.6 3.8e-05 24.4 0.1 6.7 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box_4 PF15966.5 RUS87208.1 - 4.4e-05 23.3 0.6 0.00011 22.1 0.6 1.6 1 0 0 1 1 1 1 F-box CBFD_NFYB_HMF PF00808.23 RUS87209.1 - 1.4e-12 47.7 1.3 2e-12 47.2 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS87209.1 - 0.00043 20.6 3.6 0.0008 19.8 0.0 2.2 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RUS87209.1 - 0.0005 20.2 0.0 0.0016 18.5 0.0 1.6 1 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Peroxin-3 PF04882.12 RUS87209.1 - 0.093 11.7 6.5 0.12 11.4 6.5 1.1 1 0 0 1 1 1 0 Peroxin-3 Plasmodium_Vir PF05795.11 RUS87209.1 - 0.26 10.7 3.6 0.31 10.4 3.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TP53IP5 PF15331.6 RUS87209.1 - 0.6 10.2 4.1 0.76 9.9 4.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FAM176 PF14851.6 RUS87209.1 - 3.3 7.4 6.5 6.2 6.5 6.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF2851 PF11013.8 RUS87211.1 - 0.035 13.1 0.0 46 2.8 0.0 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2851) DUF4657 PF15552.6 RUS87211.1 - 0.92 9.0 3.8 1.2 8.6 0.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4657) Synaptobrevin PF00957.21 RUS87213.1 - 7.9e-13 48.0 0.6 1.7e-12 46.9 0.6 1.6 1 0 0 1 1 1 1 Synaptobrevin Aminotran_1_2 PF00155.21 RUS87214.1 - 1.2e-41 143.1 0.0 1.3e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RUS87214.1 - 0.0011 17.5 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 RUS87214.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 RUS87214.1 - 0.0063 15.5 0.0 0.0093 14.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TPR_1 PF00515.28 RUS87215.1 - 2.2e-09 36.7 2.0 2.8e-05 23.7 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS87215.1 - 7.7e-07 28.7 3.0 0.19 11.5 0.0 4.0 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 RUS87215.1 - 8.3e-07 28.7 2.8 8.9e-05 22.3 0.1 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS87215.1 - 0.00019 21.8 0.5 0.0025 18.3 0.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS87215.1 - 0.00067 20.1 5.3 0.028 15.0 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS87215.1 - 0.00078 19.5 1.6 0.01 16.0 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS87215.1 - 0.0012 19.5 1.2 0.26 11.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS87215.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS87215.1 - 0.018 15.8 0.5 0.32 11.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 RUS87215.1 - 0.029 13.6 0.7 0.048 12.9 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FKBP_N_2 PF18023.1 RUS87215.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 BDBT FKBP like N-terminal TPR_12 PF13424.6 RUS87215.1 - 0.06 13.6 2.3 0.43 10.9 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 RUS87215.1 - 0.067 13.6 0.3 1.8 9.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain fn3_5 PF06280.12 RUS87215.1 - 0.13 12.9 0.1 0.23 12.1 0.1 1.4 1 0 0 1 1 1 0 Fn3-like domain TPR_7 PF13176.6 RUS87215.1 - 0.42 10.8 1.9 6.9 6.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Hirudin PF00713.17 RUS87215.1 - 0.46 10.8 4.4 0.26 11.6 0.5 2.4 1 1 1 2 2 2 0 Hirudin Fis1_TPR_C PF14853.6 RUS87215.1 - 0.56 10.3 3.1 0.57 10.3 0.2 2.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 RUS87215.1 - 0.62 10.6 4.1 2.8 8.5 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Lamp PF01299.17 RUS87216.1 - 2.6e-06 27.3 0.0 5.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 RUS87216.1 - 0.00018 21.4 0.2 0.00029 20.7 0.2 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TACC_C PF05010.14 RUS87217.1 - 9.4e-10 38.6 38.8 9.4e-10 38.6 38.8 2.8 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HNH_4 PF13395.6 RUS87217.1 - 0.013 15.3 4.0 4.4 7.3 0.1 4.2 2 1 2 4 4 4 0 HNH endonuclease Snurportin1 PF11538.8 RUS87217.1 - 2.9 8.1 5.2 8.5 6.7 1.4 2.8 2 0 0 2 2 2 0 Snurportin1 FOXO-TAD PF16676.5 RUS87217.1 - 6.6 7.2 6.3 6.5 7.2 1.0 3.6 3 1 1 4 4 4 0 Transactivation domain of FOXO protein family RNA_pol_Rpb4 PF03874.16 RUS87218.1 - 0.033 14.5 1.9 17 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase Rpb4 NEXCaM_BD PF16644.5 RUS87218.1 - 0.098 12.9 0.6 3.7 7.8 0.1 3.0 1 1 3 4 4 4 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Rotamase PF00639.21 RUS87219.1 - 3.8e-23 82.3 0.1 8.5e-23 81.1 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RUS87219.1 - 2.9e-19 69.7 0.0 3.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RUS87219.1 - 1e-08 35.1 0.8 1.6e-08 34.5 0.8 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 RUS87219.1 - 0.00017 22.4 0.0 0.00026 21.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 RUS87219.1 - 0.096 13.4 0.0 0.3 11.8 0.0 1.8 2 0 0 2 2 2 0 X8 domain Glyco_transf_43 PF03360.16 RUS87219.1 - 0.15 11.9 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 43 7tm_1 PF00001.21 RUS87220.1 - 2.7e-05 23.6 11.1 0.00019 20.9 11.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87220.1 - 0.006 16.2 9.9 0.0085 15.7 8.0 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Glyco_hydro_31 PF01055.26 RUS87221.1 - 4.8e-17 62.3 0.0 6.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 LIM PF00412.22 RUS87222.1 - 5.4e-34 116.2 16.5 3.4e-18 65.6 2.4 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS87222.1 - 3.1e-21 75.0 3.1 4.8e-21 74.4 3.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS87222.1 - 0.00027 20.8 0.1 0.00077 19.3 0.0 1.8 2 0 0 2 2 2 1 Homeobox KN domain Furin-like_2 PF15913.5 RUS87222.1 - 0.019 15.1 5.7 0.019 15.1 5.7 2.0 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich C1_1 PF00130.22 RUS87222.1 - 0.16 11.9 12.5 0.97 9.4 3.9 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TNFR_c6 PF00020.18 RUS87222.1 - 6.1 7.3 11.3 17 5.9 1.7 3.7 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region zf-FLZ PF04570.14 RUS87222.1 - 7.7 6.1 14.9 3.8 7.1 0.9 3.5 4 0 0 4 4 4 0 zinc-finger of the FCS-type, C2-C2 AgrB PF04647.15 RUS87223.1 - 0.011 15.1 0.3 0.016 14.5 0.3 1.2 1 0 0 1 1 1 0 Accessory gene regulator B ELM2 PF01448.24 RUS87223.1 - 0.07 13.9 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 ELM2 domain Peptidase_M32 PF02074.15 RUS87223.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase CBFD_NFYB_HMF PF00808.23 RUS87224.1 - 2.5e-19 69.3 0.2 2.5e-19 69.3 0.2 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 RUS87224.1 - 0.00022 21.4 0.4 0.00022 21.4 0.4 1.7 2 0 0 2 2 2 1 CENP-W protein Histone PF00125.24 RUS87224.1 - 0.00044 20.6 2.0 0.00053 20.4 0.0 2.0 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Activator_LAG-3 PF11498.8 RUS87224.1 - 0.026 13.5 20.6 0.028 13.4 20.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FAM222A PF15258.6 RUS87224.1 - 0.2 10.7 9.0 0.25 10.4 9.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A tRNA-synt_1g PF09334.11 RUS87226.1 - 0.077 11.7 0.1 0.21 10.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (M) Spatacsin_C PF14649.6 RUS87227.1 - 0.02 14.0 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Spatacsin C-terminus Sir1 PF11603.8 RUS87227.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Regulatory protein Sir1 Adaptin_binding PF10199.9 RUS87227.1 - 0.097 13.3 0.1 0.27 11.9 0.1 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ComP_DUS PF16732.5 RUS87227.1 - 0.1 13.5 0.2 0.18 12.7 0.2 1.3 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor P4Ha_N PF08336.11 RUS87227.1 - 0.25 11.3 3.4 1.7 8.7 1.2 2.6 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Smac_DIABLO PF09057.10 RUS87228.1 - 1.8e-22 79.8 7.6 2.3e-22 79.5 7.6 1.1 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases Knl1_RWD_C PF18210.1 RUS87228.1 - 0.046 14.2 0.1 0.25 11.9 0.0 2.1 2 1 0 2 2 2 0 Knl1 RWD C-terminal domain MMM1 PF10296.9 RUS87228.1 - 0.15 11.1 1.7 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Muted PF14942.6 RUS87228.1 - 0.18 12.2 6.6 0.24 11.7 6.0 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DHR10 PF18595.1 RUS87228.1 - 5.3 7.1 19.1 33 4.6 17.0 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain LBP_BPI_CETP_C PF02886.17 RUS87229.1 - 2.9e-39 134.9 0.0 4.3e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 RUS87229.1 - 4.4e-24 85.0 0.3 1e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain 7tm_1 PF00001.21 RUS87230.1 - 1.5e-10 40.9 11.8 2e-10 40.4 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87230.1 - 9.4e-05 22.2 16.1 9.4e-05 22.2 16.1 1.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF508 PF04370.12 RUS87230.1 - 0.056 13.2 0.8 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Yip1 PF04893.17 RUS87231.1 - 0.0019 18.0 0.3 0.0026 17.5 0.3 1.2 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 RUS87231.1 - 0.032 13.7 1.6 0.38 10.2 1.6 2.0 1 1 0 1 1 1 0 YIF1 MFS_1 PF07690.16 RUS87232.1 - 1.6e-28 99.7 22.7 8.3e-20 71.0 19.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 RUS87232.1 - 0.056 12.7 0.1 0.056 12.7 0.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Ion_trans PF00520.31 RUS87233.1 - 2.2e-32 112.2 12.2 3.4e-32 111.6 12.2 1.3 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 RUS87233.1 - 3.5e-26 91.2 0.1 7e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 RUS87233.1 - 3.4e-10 39.2 2.5 5.8e-10 38.4 2.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 RUS87233.1 - 0.00017 22.1 0.0 0.013 16.1 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS87233.1 - 0.00023 21.7 0.1 0.013 16.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS87233.1 - 0.00066 19.9 0.1 1.4 9.7 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RUS87233.1 - 0.04 14.2 0.1 12 6.4 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 RUS87233.1 - 0.15 12.6 0.0 6.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Nop14 PF04147.12 RUS87234.1 - 0.0057 15.0 23.7 0.0067 14.7 23.7 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS87234.1 - 0.0084 15.6 23.5 0.011 15.2 23.5 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 RUS87234.1 - 0.0094 14.4 13.7 0.012 14.1 13.7 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 RUS87234.1 - 0.58 8.4 20.3 0.99 7.6 20.3 1.4 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 RUS87234.1 - 3.1 6.5 5.1 3.4 6.3 5.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RUS87234.1 - 6 6.1 24.3 7.4 5.8 24.3 1.2 1 0 0 1 1 1 0 BUD22 TAFII55_N PF04658.13 RUS87236.1 - 5.1e-51 172.6 3.2 9.4e-51 171.7 3.2 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region SelK_SelG PF10961.8 RUS87236.1 - 0.0036 17.9 0.4 0.0074 16.9 0.4 1.5 1 0 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 RUS87236.1 - 0.054 14.2 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 Glycine rich protein family DUF4140 PF13600.6 RUS87236.1 - 0.22 12.0 1.8 0.24 11.9 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.6 RUS87236.1 - 0.23 11.9 7.2 0.13 12.7 5.2 1.7 1 1 0 1 1 1 0 AAA domain BRI3BP PF14965.6 RUS87236.1 - 0.23 10.9 0.3 12 5.4 0.1 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4407 PF14362.6 RUS87236.1 - 0.26 10.6 2.5 0.44 9.9 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 RUS87236.1 - 4.6 7.3 11.4 0.42 10.6 6.1 2.1 2 1 0 2 2 2 0 FlxA-like protein Mg_trans_NIPA PF05653.14 RUS87237.1 - 7.2e-226 747.5 50.0 8.4e-122 405.9 22.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 RUS87237.1 - 1.2e-09 38.5 68.2 1.7e-05 25.0 5.9 6.3 5 2 0 5 5 5 3 EamA-like transporter family DUF5383 PF17355.2 RUS87237.1 - 0.0025 18.2 5.1 11 6.4 0.1 4.7 5 0 0 5 5 5 1 Family of unknown function (DUF5383) DUF4265 PF14085.6 RUS87237.1 - 0.11 12.4 0.1 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Sprouty PF05210.13 RUS87237.1 - 0.21 12.0 3.5 13 6.3 0.4 3.4 2 2 0 2 2 2 0 Sprouty protein (Spry) ATP-synt_8 PF00895.20 RUS87237.1 - 1.9 9.0 6.9 18 5.9 0.2 3.9 4 0 0 4 4 4 0 ATP synthase protein 8 DUF4333 PF14230.6 RUS87239.1 - 0.031 14.5 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) PDZ PF00595.24 RUS87242.1 - 6.1e-07 29.7 0.1 1.8e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RUS87242.1 - 5.9e-05 22.8 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS87242.1 - 0.00027 21.2 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SNN_linker PF09050.10 RUS87242.1 - 0.16 11.7 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 Stannin unstructured linker Lig_chan PF00060.26 RUS87243.1 - 1.9e-53 180.3 0.1 3e-53 179.7 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS87243.1 - 5.8e-38 129.6 0.0 1e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RUS87243.1 - 6.6e-36 124.1 0.0 1e-35 123.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RUS87243.1 - 6.9e-26 91.1 0.0 4.4e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 RXT2_N PF08595.11 RUS87243.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Lig_chan PF00060.26 RUS87244.1 - 5.8e-50 169.0 0.2 1.2e-49 167.9 0.2 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS87244.1 - 5.5e-36 123.2 0.0 1.1e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 RUS87244.1 - 9.7e-28 97.3 0.0 1.6e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 RUS87244.1 - 1e-20 74.2 0.0 1.9e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SSF PF00474.17 RUS87246.1 - 7.9e-126 420.2 26.7 1.1e-125 419.7 26.7 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family GPAT_N PF14829.6 RUS87246.1 - 0.045 13.8 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal DUF3754 PF12576.8 RUS87246.1 - 0.059 13.3 2.7 0.94 9.4 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) zf-C4 PF00105.18 RUS87247.1 - 6.5e-23 81.0 10.5 2.8e-22 79.0 10.5 2.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS87247.1 - 0.00016 21.3 4.3 0.00016 21.3 4.3 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS87248.1 - 3.3e-22 78.7 7.8 3.3e-22 78.7 7.8 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS87248.1 - 1.6e-12 47.5 1.9 3.1e-12 46.5 1.9 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor KAP_NTPase PF07693.14 RUS87249.1 - 0.00014 21.2 0.1 0.00014 21.2 0.1 1.8 2 0 0 2 2 2 1 KAP family P-loop domain CLN3 PF02487.17 RUS87249.1 - 0.029 13.4 1.3 0.063 12.3 1.3 1.5 1 0 0 1 1 1 0 CLN3 protein Ank_2 PF12796.7 RUS87250.1 - 7.4e-59 196.3 0.3 2.4e-16 60.1 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 RUS87250.1 - 6.7e-54 183.3 0.3 1e-53 182.7 0.3 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_4 PF13637.6 RUS87250.1 - 4.8e-50 167.3 0.2 2.3e-11 44.0 0.0 7.1 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS87250.1 - 2.4e-47 157.4 0.7 4.6e-07 30.0 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 RUS87250.1 - 2.6e-43 145.5 7.4 3.1e-08 33.7 0.0 8.2 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS87250.1 - 8.5e-43 139.4 2.1 1.5e-05 25.0 0.0 9.7 9 0 0 9 9 9 9 Ankyrin repeat NACHT PF05729.12 RUS87250.1 - 0.012 15.5 0.6 0.65 9.9 0.1 2.7 2 0 0 2 2 2 0 NACHT domain YfhO PF09586.10 RUS87250.1 - 0.34 9.1 2.6 0.53 8.5 2.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SP_C-Propep PF08999.10 RUS87250.1 - 0.47 10.3 5.3 0.21 11.4 0.5 2.4 1 1 1 2 2 2 0 Surfactant protein C, N terminal propeptide DUF1129 PF06570.11 RUS87250.1 - 0.64 9.5 4.0 1.4 8.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2207 PF09972.9 RUS87250.1 - 1.5 7.5 7.8 3.2 6.4 1.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Myelin_PLP PF01275.19 RUS87251.1 - 4.3e-46 157.7 10.2 5.2e-46 157.4 10.2 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) SLATT_1 PF18181.1 RUS87251.1 - 3.5 7.6 4.2 9.8 6.1 0.1 2.8 1 1 3 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 Rab5ip PF07019.12 RUS87252.1 - 1.1e-18 67.5 13.8 1.4e-18 67.2 13.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sulfotransfer_1 PF00685.27 RUS87253.1 - 2.4e-11 43.6 0.1 2e-07 30.8 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS87253.1 - 1e-10 42.3 0.0 4.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Phage_HK97_TLTM PF06120.11 RUS87253.1 - 0.046 12.9 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 Tail length tape measure protein RhoGAP PF00620.27 RUS87254.1 - 3.3e-45 153.6 0.0 9.9e-45 152.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DUF2407_C PF13373.6 RUS87254.1 - 0.016 15.4 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain Acetyltransf_11 PF13720.6 RUS87254.1 - 0.15 12.5 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 APC_u14 PF16635.5 RUS87255.1 - 1.2 9.7 6.2 0.81 10.3 2.7 2.5 1 1 1 2 2 2 0 Unstructured region on APC between SAMP and APC_crr SCHIP-1 PF10148.9 RUS87255.1 - 1.5 8.3 4.8 2 8.0 4.0 1.7 1 1 0 1 1 1 0 Schwannomin-interacting protein 1 DUF637 PF04830.13 RUS87257.1 - 0.00033 20.5 0.3 1.1 9.0 0.1 3.1 1 1 1 2 2 2 2 Possible hemagglutinin (DUF637) Ependymin PF00811.18 RUS87258.1 - 3.3e-12 46.8 0.0 5.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ependymin Peptidase_C32 PF05411.12 RUS87258.1 - 0.023 14.6 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF4573 PF15140.6 RUS87260.1 - 1.2e-08 34.9 16.4 7.1e-07 29.2 4.7 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4573) HTH_10 PF04967.12 RUS87260.1 - 0.0094 15.7 8.7 88 3.0 0.1 7.1 2 2 7 10 10 10 0 HTH DNA binding domain Phage_Coat_A PF05357.13 RUS87260.1 - 0.022 14.5 8.7 53 3.7 0.4 6.5 2 2 4 6 6 6 0 Phage Coat Protein A RelB_N PF18506.1 RUS87260.1 - 0.53 10.1 0.1 0.53 10.1 0.1 6.1 3 3 4 8 8 8 0 RelB Antitoxin alpha helical domain HTH_54 PF18607.1 RUS87260.1 - 1.8 8.7 8.5 13 5.9 0.2 4.9 1 1 6 7 7 7 0 ParA helix turn helix domain Acetyltransf_CG PF14542.6 RUS87262.1 - 3.5 7.8 44.7 86 3.4 0.4 10.9 1 1 17 18 18 18 0 GCN5-related N-acetyl-transferase Nucleocapsid-N PF11030.8 RUS87263.1 - 0.73 9.8 17.5 25 4.7 0.6 4.7 1 1 6 7 7 7 0 Nucleocapsid protein N PX PF00787.24 RUS87264.1 - 9.2e-15 54.6 0.3 2.6e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 RUS87264.1 - 7.1e-05 22.5 7.6 0.032 13.8 2.3 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 RUS87264.1 - 0.00024 20.8 4.4 0.0003 20.5 4.0 1.4 1 1 0 1 1 1 1 BAR domain HopW1-1 PF15457.6 RUS87264.1 - 0.0043 16.4 0.1 0.0059 15.9 0.1 1.2 1 0 0 1 1 1 1 Type III T3SS secreted effector HopW1-1/HopPmaA DUF2524 PF10732.9 RUS87264.1 - 0.16 12.3 2.0 3.2 8.1 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Nup96 PF12110.8 RUS87265.1 - 1.4e-90 303.3 12.8 2.1e-90 302.8 12.8 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 RUS87265.1 - 1.1e-44 152.1 0.0 2.1e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase DNA_pol_A_exo1 PF01612.20 RUS87266.1 - 1.1e-09 38.3 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease LSM14 PF12701.7 RUS87266.1 - 0.0022 18.1 0.1 0.0085 16.2 0.1 2.0 2 0 0 2 2 2 1 Scd6-like Sm domain DUF812 PF05667.11 RUS87267.1 - 6.3e-201 669.3 42.4 6.5e-114 382.0 41.7 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF812) Hemerythrin PF01814.23 RUS87267.1 - 0.13 12.8 0.1 0.13 12.8 0.1 3.3 2 1 0 3 3 3 0 Hemerythrin HHE cation binding domain BRCC36_C PF18110.1 RUS87267.1 - 0.14 12.3 2.2 1 9.6 1.3 2.7 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain HALZ PF02183.18 RUS87267.1 - 0.5 10.6 12.4 1.4 9.2 0.1 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF2203 PF09969.9 RUS87267.1 - 0.77 10.5 31.4 0.21 12.3 1.8 4.2 2 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Occludin_ELL PF07303.13 RUS87267.1 - 1.2 9.9 30.6 1 10.1 0.6 4.1 3 1 1 4 4 4 0 Occludin homology domain TACC_C PF05010.14 RUS87267.1 - 1.5 8.5 44.4 3.3 7.4 15.4 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Nairo_nucleo PF02477.15 RUS87267.1 - 4.1 6.1 11.6 0.94 8.2 1.1 2.1 1 1 1 2 2 2 0 Nucleocapsid N protein MspA PF09203.11 RUS87268.1 - 2.7e-05 24.1 23.7 7 6.5 23.7 2.9 1 1 0 1 1 1 1 MspA DUF1943 PF09172.11 RUS87268.1 - 0.00014 21.2 34.8 1.8e+04 -6.4 34.8 3.0 1 1 0 1 1 0 0 Domain of unknown function (DUF1943) DUF481 PF04338.12 RUS87268.1 - 0.0043 17.1 0.2 0.21 11.6 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF481 CopB PF05275.11 RUS87268.1 - 0.0048 16.5 1.4 1.7 8.2 0.2 2.8 1 1 2 3 3 3 2 Copper resistance protein B precursor (CopB) OMP_b-brl_2 PF13568.6 RUS87268.1 - 0.0065 16.5 9.1 24 4.9 0.2 3.9 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain CEL_III_C PF18054.1 RUS87268.1 - 0.013 15.5 23.4 8.1e+03 -3.2 23.4 2.9 1 1 0 1 1 1 0 CEL-III C-terminal PorP_SprF PF11751.8 RUS87268.1 - 0.052 13.1 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 Type IX secretion system membrane protein PorP/SprF TamB PF04357.13 RUS87268.1 - 0.19 11.0 19.8 1.5e+04 -5.2 19.8 3.2 1 1 0 1 1 0 0 TamB, inner membrane protein subunit of TAM complex DUF4390 PF14334.6 RUS87268.1 - 0.27 10.6 8.5 27 4.2 0.3 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4390) DUF1062 PF06353.12 RUS87268.1 - 0.37 11.6 19.3 1.8e+04 -6.4 19.3 4.0 1 1 0 1 1 0 0 Protein of unknown function (DUF1062) DUF2715 PF10895.8 RUS87268.1 - 0.37 10.4 20.8 5.1e+03 -3.1 20.8 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) Aerolysin PF01117.20 RUS87268.1 - 1.2 8.3 15.1 3.2 6.9 3.8 2.1 1 1 1 2 2 2 0 Aerolysin toxin WD40 PF00400.32 RUS87269.1 - 1.1e-48 162.1 33.1 8.9e-11 42.2 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS87269.1 - 1.1e-20 73.7 6.8 3.8e-05 23.9 0.0 5.4 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS87269.1 - 4.9e-07 29.8 0.4 0.00017 21.5 0.1 3.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 RUS87269.1 - 0.00032 18.9 0.5 0.0013 16.8 0.4 1.9 1 1 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 RUS87269.1 - 0.0022 17.0 4.7 0.99 8.3 0.0 4.4 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 RUS87269.1 - 0.0088 15.1 0.1 0.75 8.8 0.0 3.3 3 1 1 4 4 4 1 Coatomer WD associated region LRR_8 PF13855.6 RUS87271.1 - 1.2e-31 108.3 32.9 1.2e-08 34.6 1.1 3.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RUS87271.1 - 2.9e-18 65.7 36.5 3.3e-07 30.5 2.2 5.2 1 1 7 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS87271.1 - 4.3e-08 32.8 8.0 9.9e-06 25.2 1.6 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RUS87271.1 - 9.3e-08 31.6 13.8 2.7 8.9 0.1 7.4 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 RUS87271.1 - 0.0063 16.5 21.1 7.1 7.0 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat RsmF_methylt_CI PF17126.5 RUS87271.1 - 0.033 14.2 0.0 3.8 7.6 0.0 3.0 2 1 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain NKWYS PF10364.9 RUS87271.1 - 0.057 13.5 0.3 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Putative capsular polysaccharide synthesis protein FAM181 PF15238.6 RUS87272.1 - 4.8e-19 69.3 12.9 4.8e-19 69.3 12.9 2.5 1 1 2 3 3 3 1 FAM181 Tho2 PF11262.8 RUS87273.1 - 2.2e-100 335.8 4.8 2.2e-100 335.8 4.8 3.9 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 RUS87273.1 - 1.4e-84 284.9 2.6 1.4e-59 202.4 4.3 5.1 2 2 2 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 RUS87273.1 - 3.4e-34 116.7 0.1 1.2e-33 115.0 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit TPR_19 PF14559.6 RUS87273.1 - 0.0008 19.9 0.3 0.003 18.0 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Nop14 PF04147.12 RUS87274.1 - 0.00015 20.2 33.2 0.00017 20.0 33.2 1.0 1 0 0 1 1 1 1 Nop14-like family COPI_C PF06957.11 RUS87274.1 - 0.0066 15.3 9.0 0.0074 15.1 9.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Mpp10 PF04006.12 RUS87274.1 - 0.014 13.9 25.2 0.018 13.5 25.2 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS87274.1 - 0.031 13.7 41.1 0.038 13.4 41.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RUS87274.1 - 4 6.7 39.3 5.5 6.2 39.3 1.1 1 0 0 1 1 1 0 BUD22 CD36 PF01130.21 RUS87275.1 - 6.5e-110 367.8 2.5 1.3e-109 366.9 2.5 1.3 1 1 0 1 1 1 1 CD36 family NUMOD4 PF07463.11 RUS87276.1 - 0.0088 16.2 0.9 99 3.3 0.0 5.0 6 0 0 6 6 6 0 NUMOD4 motif Spp-24 PF07448.11 RUS87276.1 - 0.54 10.5 9.5 26 5.1 0.3 4.3 1 1 4 5 5 5 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Histidinol_dh PF00815.20 RUS87276.1 - 2.9 6.8 4.9 16 4.4 0.5 2.5 1 1 2 3 3 3 0 Histidinol dehydrogenase Galanin PF01296.18 RUS87276.1 - 5.4 7.1 8.0 3.5e+02 1.3 0.1 5.1 6 0 0 6 6 6 0 Galanin Neur_chan_LBD PF02931.23 RUS87277.1 - 8.2e-44 149.6 0.0 1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS87277.1 - 2e-07 31.3 0.5 2.9e-07 30.8 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.11 RUS87278.1 - 9e-07 28.9 91.8 1.8e+04 -28.9 91.8 2.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_20 PF14561.6 RUS87278.1 - 0.075 13.4 0.3 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sdh5 PF03937.16 RUS87279.1 - 2.3e-05 24.3 9.3 44 4.1 0.0 7.5 1 1 7 10 10 10 0 Flavinator of succinate dehydrogenase TryThrA_C PF12319.8 RUS87279.1 - 3.8e-05 23.3 10.5 0.0075 15.8 2.2 2.5 1 1 1 2 2 2 2 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF445 PF04286.12 RUS87279.1 - 0.0028 17.5 10.0 0.0036 17.2 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Sep15_SelM PF08806.11 RUS87279.1 - 0.37 11.0 12.3 9.7 6.4 0.8 6.3 2 2 3 5 5 5 0 Sep15/SelM redox domain ArfGap PF01412.18 RUS87279.1 - 5.7 7.0 24.0 35 4.5 5.0 5.1 1 1 2 3 3 3 0 Putative GTPase activating protein for Arf Neur_chan_LBD PF02931.23 RUS87280.1 - 8.1e-35 120.2 1.4 1.2e-34 119.7 1.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS87280.1 - 5.6e-24 85.5 3.9 2.4e-23 83.5 3.9 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SH3_6 PF12913.7 RUS87280.1 - 0.0079 15.7 0.0 0.027 14.0 0.0 1.9 1 0 0 1 1 1 1 SH3 domain (SH3b1 type) DUF1218 PF06749.12 RUS87280.1 - 0.092 13.3 2.5 0.31 11.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF2583 PF10762.9 RUS87280.1 - 0.27 11.7 0.9 14 6.2 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) ABC2_membrane_5 PF13346.6 RUS87280.1 - 0.59 9.7 12.7 0.064 12.8 7.3 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein GST_C_3 PF14497.6 RUS87281.1 - 7.2e-21 74.2 1.1 1.2e-20 73.6 1.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS87281.1 - 2.3e-07 31.0 0.1 2.2e-05 24.7 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS87281.1 - 2.7e-05 24.3 0.3 4.9e-05 23.5 0.2 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS87281.1 - 0.00044 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain E1_DerP2_DerF2 PF02221.15 RUS87284.1 - 2.6e-05 24.7 0.0 3.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ML domain Pam16 PF03656.13 RUS87285.1 - 1.2e-45 154.6 4.8 1.3e-45 154.5 4.8 1.0 1 0 0 1 1 1 1 Pam16 DUF719 PF05334.13 RUS87286.1 - 5e-41 141.0 12.4 5e-41 141.0 12.4 5.0 3 2 0 3 3 3 1 Protein of unknown function (DUF719) NHL PF01436.21 RUS87287.1 - 8.7e-11 41.3 2.4 0.00015 21.6 0.0 3.7 3 0 0 3 3 3 3 NHL repeat zf-RING_UBOX PF13445.6 RUS87287.1 - 0.0019 18.2 8.6 0.0019 18.2 8.6 2.3 2 1 0 2 2 2 1 RING-type zinc-finger Methyltransf_8 PF05148.15 RUS87288.1 - 2.5e-82 276.0 0.1 4.9e-82 275.0 0.1 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 RUS87288.1 - 4.7e-06 27.2 0.1 6.6e-05 23.5 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS87288.1 - 0.00041 21.0 0.0 0.047 14.4 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS87288.1 - 0.0034 16.9 1.1 0.045 13.3 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_32 PF13679.6 RUS87288.1 - 0.032 14.2 0.0 0.032 14.2 0.0 5.4 2 1 0 2 2 2 0 Methyltransferase domain FH2 PF02181.23 RUS87289.1 - 6.8e-97 324.9 12.0 6.8e-97 324.9 12.0 1.9 1 1 1 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RUS87289.1 - 1.6e-49 168.2 0.0 1.6e-49 168.2 0.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RUS87289.1 - 5.8e-14 52.1 0.0 5.8e-14 52.1 0.0 3.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_DAD PF06345.11 RUS87289.1 - 1.3e-06 28.0 0.3 1.3e-06 28.0 0.3 2.2 2 0 0 2 2 2 1 DRF Autoregulatory Domain D5_N PF08706.11 RUS87289.1 - 0.64 10.3 3.8 2.8 8.2 3.8 2.1 1 0 0 1 1 1 0 D5 N terminal like APG6_N PF17675.1 RUS87289.1 - 0.77 10.3 27.0 0.99 9.9 3.5 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Drf_GBD PF06371.13 RUS87290.1 - 5.2e-17 62.0 0.2 5.2e-17 62.0 0.2 1.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain efThoc1 PF11957.8 RUS87290.1 - 0.023 13.4 3.0 0.029 13.1 3.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor RMI1_N PF08585.12 RUS87291.1 - 4.1e-21 75.7 0.1 2.4e-17 63.4 0.0 3.1 2 1 1 3 3 3 2 RecQ mediated genome instability protein SMN PF06003.12 RUS87291.1 - 1.2e-07 31.2 0.0 1.2e-07 31.2 0.0 3.5 3 1 0 4 4 4 1 Survival motor neuron protein (SMN) UBA PF00627.31 RUS87291.1 - 3.7e-06 26.7 0.2 6.4e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain TUDOR PF00567.24 RUS87291.1 - 0.00015 21.7 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF1325 PF07039.11 RUS87291.1 - 0.0024 18.0 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 RUS87291.1 - 0.0041 17.1 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 RUS87291.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Linker_histone PF00538.19 RUS87292.1 - 1.3e-28 99.2 1.3 1.3e-28 99.2 1.3 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Linker_histone PF00538.19 RUS87293.1 - 1.3e-28 99.2 1.3 1.3e-28 99.2 1.3 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family RNase_H PF00075.24 RUS87294.1 - 9.6e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 RUS87294.1 - 0.00049 19.9 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DUF2482 PF10655.9 RUS87295.1 - 0.14 12.6 6.1 21 5.7 0.5 3.9 1 1 4 5 5 5 0 Hypothetical protein of unknown function (DUF2482) Arteri_Gl PF00951.18 RUS87295.1 - 1.3 8.8 11.3 1.9 8.2 2.8 2.1 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein IBN_N PF03810.19 RUS87296.1 - 2.3e-05 24.2 0.1 0.00014 21.7 0.1 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain TPPK_C PF12555.8 RUS87297.1 - 0.00082 19.4 22.0 4.1e+02 1.1 0.0 11.9 1 1 22 24 24 24 0 Thiamine pyrophosphokinase C terminal 7tm_4 PF13853.6 RUS87297.1 - 2 8.1 10.1 28 4.3 0.3 4.0 1 1 2 3 3 3 0 Olfactory receptor RVT_1 PF00078.27 RUS87298.1 - 1.2e-14 54.4 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 RUS87298.1 - 0.00086 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 RUS87298.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 RUS87299.1 - 3e-29 102.6 0.0 4.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HLH PF00010.26 RUS87300.1 - 1.4e-16 60.2 3.0 2.1e-16 59.6 3.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS87300.1 - 8.4e-12 45.1 0.3 1.6e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 Hairy Orange MRP-S35 PF10246.9 RUS87301.1 - 5.5e-41 138.8 0.0 8.2e-41 138.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.23 RUS87301.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain HD_3 PF13023.6 RUS87302.1 - 1.9e-37 128.7 0.0 2.7e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 RUS87302.1 - 9.3e-13 48.3 0.4 9.5e-12 45.0 0.4 2.0 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 RUS87302.1 - 6.3e-06 26.4 0.1 2.7e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 HD domain EF-hand_5 PF13202.6 RUS87303.1 - 8e-05 22.0 0.2 0.00016 21.0 0.2 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 RUS87303.1 - 0.00014 21.2 0.1 0.00023 20.5 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RUS87303.1 - 0.0017 18.1 0.1 0.0034 17.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 RUS87303.1 - 0.026 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 RUS87303.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair NCD2 PF04905.13 RUS87304.1 - 4.4e-48 162.4 0.0 9.9e-48 161.2 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) Tim54 PF11711.8 RUS87304.1 - 3.3 6.4 6.7 7.2 5.3 6.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRP1_N PF06424.12 RUS87304.1 - 3.8 7.9 11.2 99 3.3 0.0 3.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Herpes_BLLF1 PF05109.13 RUS87305.1 - 0.37 8.7 42.5 0.47 8.4 42.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RIFIN PF02009.16 RUS87305.1 - 3.8 7.3 13.1 2.5 7.9 0.1 2.1 1 1 1 2 2 2 0 Rifin BUD22 PF09073.10 RUS87306.1 - 0.0023 17.4 5.8 0.0032 16.9 5.8 1.2 1 0 0 1 1 1 1 BUD22 ABC_tran_2 PF16949.5 RUS87306.1 - 0.094 11.5 3.4 0.13 11.1 3.4 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette Rhabdo_ncap PF00945.18 RUS87306.1 - 0.45 9.4 7.9 0.77 8.6 7.9 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DNA_pol_phi PF04931.13 RUS87306.1 - 0.48 8.5 20.9 0.82 7.7 20.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 RUS87306.1 - 3.3 7.4 9.0 0.32 10.7 3.7 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SGT1 PF07093.11 RUS87306.1 - 6 5.2 8.2 10 4.4 8.2 1.3 1 0 0 1 1 1 0 SGT1 protein SDA1 PF05285.12 RUS87306.1 - 7.6 5.9 17.5 0.48 9.8 8.6 2.1 2 0 0 2 2 2 0 SDA1 Herpes_pp85 PF04637.12 RUS87306.1 - 8.9 4.6 8.5 13 4.1 8.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Lectin_C PF00059.21 RUS87307.1 - 0.34 11.6 3.1 4.6 8.0 0.0 2.7 2 1 1 3 3 3 0 Lectin C-type domain Ank_2 PF12796.7 RUS87309.1 - 6.9e-13 49.0 3.7 1.1e-09 38.7 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RUS87309.1 - 1.8e-11 44.0 0.1 1e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RUS87309.1 - 4.5e-10 38.9 0.0 0.00022 21.4 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RUS87309.1 - 1.2e-09 38.5 0.2 0.0021 18.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 RUS87309.1 - 3.9e-09 36.4 16.7 3.9e-09 36.4 16.7 1.8 2 0 0 2 2 2 1 MYND finger Ank_5 PF13857.6 RUS87309.1 - 4e-06 27.0 0.4 0.033 14.5 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-C6H2 PF15801.5 RUS87309.1 - 0.27 11.6 12.2 0.5 10.7 12.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 RUS87309.1 - 0.28 9.0 9.3 0.45 8.3 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DDHD PF02862.17 RUS87309.1 - 0.38 10.9 4.2 0.92 9.6 4.2 1.6 1 0 0 1 1 1 0 DDHD domain DUF1682 PF07946.14 RUS87309.1 - 4.2 6.5 12.5 2.3 7.3 9.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) ANAPC4_WD40 PF12894.7 RUS87310.1 - 1.7e-06 28.3 0.0 0.027 14.8 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS87310.1 - 0.00031 21.5 3.5 0.007 17.2 0.6 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat CPSF_A PF03178.15 RUS87310.1 - 0.012 15.0 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region Ge1_WD40 PF16529.5 RUS87310.1 - 0.017 14.1 0.0 0.56 9.1 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 RUS87310.1 - 0.047 13.3 0.3 0.69 9.5 0.0 2.3 1 1 0 2 2 2 0 CNH domain Utp8 PF10395.9 RUS87310.1 - 0.064 11.8 0.1 0.27 9.7 0.0 1.7 1 1 1 2 2 2 0 Utp8 family TMEM154 PF15102.6 RUS87311.1 - 0.025 14.5 0.3 0.025 14.5 0.3 2.5 3 0 0 3 3 3 0 TMEM154 protein family Insulin_TMD PF17870.1 RUS87311.1 - 0.039 14.0 0.5 0.084 13.0 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF3810 PF12725.7 RUS87311.1 - 0.06 12.7 0.2 0.097 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Orf78 PF06024.12 RUS87311.1 - 0.13 12.6 1.3 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Cadherin_C_2 PF16492.5 RUS87311.1 - 0.21 12.4 0.2 0.21 12.4 0.2 3.1 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal SIT PF15330.6 RUS87311.1 - 0.22 12.0 0.8 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Lectin_C PF00059.21 RUS87312.1 - 1.3e-20 74.1 0.7 9.6e-08 32.7 0.0 3.3 3 0 0 3 3 3 3 Lectin C-type domain Chordopox_A33R PF05966.12 RUS87312.1 - 2.6e-05 23.6 1.3 0.17 11.2 0.0 3.2 2 1 1 3 3 3 3 Chordopoxvirus A33R protein Xlink PF00193.17 RUS87312.1 - 0.0098 16.3 0.8 1.1 9.7 0.1 3.3 3 0 0 3 3 3 1 Extracellular link domain BORCS6 PF10157.9 RUS87313.1 - 0.13 12.5 1.3 0.2 11.9 1.3 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF5409 PF17421.2 RUS87314.1 - 0.22 12.2 12.6 1.5 9.6 2.3 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5409) DUF2968 PF11180.8 RUS87314.1 - 0.64 9.6 0.1 0.64 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) RGS PF00615.19 RUS87315.1 - 1.9e-33 115.2 0.3 2.1e-33 115.1 0.3 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4472 PF14739.6 RUS87317.1 - 3.8e-30 104.8 15.6 3.8e-30 104.8 15.6 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF4472) Kinesin PF00225.23 RUS87317.1 - 5.2e-16 58.5 0.0 1.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain BBP1_C PF15272.6 RUS87317.1 - 0.01 15.6 10.4 0.01 15.6 10.4 4.6 4 1 0 4 4 4 0 Spindle pole body component BBP1, C-terminal Scaffolding_pro PF11418.8 RUS87317.1 - 0.13 12.9 0.3 0.13 12.9 0.3 5.1 5 0 0 5 5 5 0 Phi29 scaffolding protein ACP_PD PF04336.12 RUS87317.1 - 4.1 7.9 10.2 17 5.9 0.4 4.0 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase Synaptobrevin PF00957.21 RUS87317.1 - 5.5 6.9 13.8 5.5 6.9 2.0 3.5 2 1 1 3 3 3 0 Synaptobrevin DUF4407 PF14362.6 RUS87317.1 - 8.7 5.6 36.1 5 6.4 7.2 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Fibrinogen_C PF00147.18 RUS87318.1 - 3.6e-53 180.6 3.2 4.9e-53 180.2 3.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Syntaxin-6_N PF09177.11 RUS87318.1 - 0.14 12.7 0.4 0.3 11.7 0.4 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 RUS87318.1 - 0.44 10.5 2.6 0.89 9.5 2.6 1.4 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 RUS87318.1 - 1.5 9.3 4.2 25 5.4 0.3 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein T3SS_basalb_I PF17001.5 RUS87322.1 - 0.026 15.1 2.2 0.041 14.5 2.2 1.3 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI TFIIA PF03153.13 RUS87322.1 - 0.21 11.5 7.1 0.24 11.4 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 RUS87322.1 - 0.33 9.4 2.9 0.39 9.2 2.9 1.2 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 RUS87322.1 - 0.64 8.2 7.8 0.73 8.0 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1631 PF07793.11 RUS87322.1 - 1.4 7.3 9.0 1.7 7.0 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SelP_N PF04592.14 RUS87322.1 - 3.3 7.0 23.1 4.6 6.6 23.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-C4 PF00105.18 RUS87323.1 - 1.3e-31 108.9 11.5 1.3e-31 108.9 11.5 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS87323.1 - 0.0035 16.9 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SUIM_assoc PF16619.5 RUS87323.1 - 0.1 12.7 5.6 0.23 11.6 2.0 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glycos_transf_2 PF00535.26 RUS87324.1 - 8e-21 74.6 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS87324.1 - 8.8e-11 42.2 0.5 1.5e-10 41.5 0.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 RUS87324.1 - 3.9e-05 23.6 0.0 0.00061 19.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RUS87324.1 - 9.4e-05 22.0 0.0 0.00033 20.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_31 PF13847.6 RUS87325.1 - 8.2e-14 51.7 0.1 8.9e-06 25.6 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RUS87325.1 - 2.9e-12 47.1 0.2 6.8e-10 39.5 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS87325.1 - 7e-11 42.6 0.1 1.5e-09 38.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS87325.1 - 3.7e-10 40.4 0.3 2.2e-08 34.7 0.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS87325.1 - 2.2e-09 37.3 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 RUS87325.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain NAS PF03059.16 RUS87325.1 - 0.0051 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein DREV PF05219.12 RUS87325.1 - 0.08 12.0 0.0 0.76 8.8 0.0 2.0 1 1 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 RUS87325.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HTH_22 PF13309.6 RUS87325.1 - 0.12 12.5 0.2 0.32 11.1 0.2 1.7 2 0 0 2 2 2 0 HTH domain FEZ PF07763.13 RUS87326.1 - 2.3e-53 181.4 4.6 3.1e-53 181.0 4.6 1.1 1 0 0 1 1 1 1 FEZ-like protein NAD_binding_10 PF13460.6 RUS87326.1 - 0.017 15.0 0.2 0.028 14.3 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Forkhead PF00250.18 RUS87327.1 - 2.8e-33 114.0 0.3 8e-33 112.6 0.1 2.0 2 0 0 2 2 2 1 Forkhead domain TFIIA PF03153.13 RUS87327.1 - 0.00027 21.1 8.7 0.00027 21.1 8.7 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1676 PF07898.13 RUS87327.1 - 0.00056 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) NOA36 PF06524.12 RUS87327.1 - 0.0068 15.8 25.6 0.014 14.7 25.6 1.4 1 0 0 1 1 1 1 NOA36 protein Sigma70_ner PF04546.13 RUS87327.1 - 0.25 11.2 12.5 0.5 10.2 12.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RUS87327.1 - 0.79 7.9 19.1 1.8 6.7 19.1 1.5 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS87327.1 - 1.5 6.8 35.2 2.6 6.1 35.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS87327.1 - 8.4 4.8 21.2 15 4.0 21.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rota_NS6 PF04866.12 RUS87329.1 - 0.022 15.0 0.3 0.038 14.2 0.3 1.6 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 CPG4 PF15481.6 RUS87329.1 - 0.34 11.6 8.6 0.1 13.2 4.2 2.1 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 WW PF00397.26 RUS87330.1 - 5.9e-08 32.7 3.2 5.9e-08 32.7 3.2 2.4 2 0 0 2 2 2 1 WW domain WD40 PF00400.32 RUS87331.1 - 4.2e-17 62.2 1.9 6.8e-05 23.6 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS87331.1 - 4e-06 27.0 0.0 0.06 13.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS87331.1 - 0.0013 18.1 0.0 0.012 15.0 0.0 2.1 2 1 1 3 3 3 1 WD40-like domain CortBP2 PF09727.9 RUS87332.1 - 2.1e-72 243.1 14.6 2.1e-72 243.1 14.6 2.7 3 0 0 3 3 3 1 Cortactin-binding protein-2 Ank_2 PF12796.7 RUS87332.1 - 1e-24 86.9 6.5 4.1e-12 46.5 0.3 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS87332.1 - 1.9e-20 72.9 6.0 7.1e-10 39.2 0.4 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS87332.1 - 1.4e-13 49.7 6.0 0.035 14.6 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RUS87332.1 - 1.6e-13 50.6 6.7 1.3e-07 31.7 0.2 4.9 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS87332.1 - 1.4e-11 44.3 7.9 0.0021 18.5 0.6 4.6 4 0 0 4 4 4 3 Ankyrin repeat AAA_22 PF13401.6 RUS87332.1 - 0.0002 21.6 0.6 0.0014 18.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RUS87332.1 - 0.00034 21.0 0.0 0.0015 19.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 RUS87332.1 - 0.00056 20.3 0.1 0.0019 18.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 RUS87332.1 - 0.0013 18.7 0.0 0.0055 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 RUS87332.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 RUS87332.1 - 0.0027 17.6 2.4 0.0031 17.5 0.0 2.4 3 0 0 3 3 2 1 NACHT domain AAA PF00004.29 RUS87332.1 - 0.0065 16.9 0.2 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RUS87332.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 RUS87332.1 - 0.038 14.2 0.7 0.21 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RUS87332.1 - 0.038 13.5 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3037 PF11236.8 RUS87332.1 - 0.23 11.9 9.8 3.4 8.1 3.8 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3037) Pkinase PF00069.25 RUS87333.1 - 2.4e-42 145.1 0.0 4.7e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87333.1 - 7.3e-38 130.3 0.0 1.3e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.22 RUS87333.1 - 6.2e-05 23.1 0.0 0.00021 21.4 0.0 2.0 1 0 0 1 1 1 1 Death domain Pyr_redox_2 PF07992.14 RUS87334.1 - 1.7e-68 231.1 4.0 9e-68 228.6 3.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RUS87334.1 - 7.4e-40 135.6 0.3 1.6e-39 134.6 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RUS87334.1 - 1.7e-20 73.4 4.4 1.5e-16 60.7 1.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RUS87334.1 - 1.3e-09 38.0 9.1 3.1e-09 36.7 0.0 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RUS87334.1 - 1.6e-08 34.1 1.8 1.9e-07 30.5 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 RUS87334.1 - 1.6e-08 34.2 1.4 8.6e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS87334.1 - 6.5e-08 32.1 1.9 3.5e-07 29.6 0.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RUS87334.1 - 6.8e-08 32.1 5.7 0.0019 17.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 RUS87334.1 - 2.9e-06 27.4 1.6 0.0005 20.2 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 RUS87334.1 - 3.4e-06 26.0 2.7 0.0019 16.9 0.2 3.0 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 RUS87334.1 - 1.8e-05 24.1 0.3 0.65 9.1 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 RUS87334.1 - 0.0018 17.6 0.1 0.0018 17.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 RUS87334.1 - 0.0024 17.5 6.4 0.87 9.1 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RUS87334.1 - 0.022 14.1 6.2 0.9 8.8 0.3 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 RUS87334.1 - 0.06 12.6 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UPF0227 PF05728.12 RUS87334.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) 2-Hacid_dh_C PF02826.19 RUS87334.1 - 0.57 9.5 2.0 5.1 6.4 0.1 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 RUS87334.1 - 0.91 9.1 4.2 17 4.9 0.9 3.2 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 RUS87334.1 - 0.94 8.5 4.8 0.72 8.8 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Fez1 PF06818.15 RUS87335.1 - 1.3e-07 32.3 187.9 0.012 16.0 28.5 8.4 1 1 7 8 8 8 6 Fez1 Spc7 PF08317.11 RUS87335.1 - 1.1e-05 24.5 207.2 0.076 11.9 27.6 8.8 1 1 8 9 9 9 6 Spc7 kinetochore protein zf-Di19 PF05605.12 RUS87335.1 - 1.7e-05 25.0 1.5 0.091 13.1 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RUS87335.1 - 1.9e-05 25.1 4.5 0.16 12.9 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger KASH_CCD PF14662.6 RUS87335.1 - 8.5e-05 22.5 16.3 8.5e-05 22.5 16.3 9.1 1 1 6 8 8 6 1 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 RUS87335.1 - 0.00035 18.9 17.4 0.00035 18.9 17.4 7.4 1 1 6 7 7 6 5 Filament-like plant protein, long coiled-coil zf-C2H2 PF00096.26 RUS87335.1 - 0.00059 20.1 3.4 0.023 15.1 0.2 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type TPR_MLP1_2 PF07926.12 RUS87335.1 - 0.00077 19.5 224.1 0.019 15.0 11.6 11.5 1 1 8 10 10 10 4 TPR/MLP1/MLP2-like protein zf_UBZ PF18439.1 RUS87335.1 - 0.00089 18.8 1.3 0.97 9.1 0.1 2.8 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger BRE1 PF08647.11 RUS87335.1 - 0.0058 16.7 10.3 0.0058 16.7 10.3 12.7 2 2 9 13 13 10 2 BRE1 E3 ubiquitin ligase Cnn_1N PF07989.11 RUS87335.1 - 0.006 16.7 9.9 0.006 16.7 9.9 15.4 3 3 12 15 15 9 2 Centrosomin N-terminal motif 1 zf-C2H2_9 PF16293.5 RUS87335.1 - 0.015 15.2 9.2 1.4 8.8 0.1 4.6 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) DUF3800 PF12686.7 RUS87335.1 - 0.02 15.5 4.1 1.6e+02 2.9 4.1 5.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) zf-met PF12874.7 RUS87335.1 - 0.026 14.9 0.3 0.4 11.1 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 RUS87335.1 - 0.13 11.9 6.5 0.21 11.3 0.0 3.6 4 0 0 4 4 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Myosin_tail_1 PF01576.19 RUS87335.1 - 0.16 9.7 201.7 0.092 10.5 38.9 5.4 1 1 4 5 5 5 0 Myosin tail ERM PF00769.19 RUS87335.1 - 0.24 11.2 210.2 1.1 9.0 39.0 7.5 1 1 5 7 7 7 0 Ezrin/radixin/moesin family zf-C2H2_2 PF12756.7 RUS87335.1 - 0.26 11.6 4.0 11 6.5 0.1 3.8 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) MAD PF05557.13 RUS87335.1 - 0.53 8.6 192.4 0.048 12.0 39.1 6.2 1 1 5 6 6 6 0 Mitotic checkpoint protein zf-C2H2_jaz PF12171.8 RUS87335.1 - 0.86 10.0 2.7 11 6.5 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding HMMR_N PF15905.5 RUS87335.1 - 1.2 8.5 209.5 0.062 12.8 18.5 8.7 1 1 8 9 9 9 0 Hyaluronan mediated motility receptor N-terminal Peptidase_C14 PF00656.22 RUS87336.1 - 1.6e-12 47.9 0.0 1.9e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain S_100 PF01023.19 RUS87336.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain CLIP_SPH_mas PF18398.1 RUS87337.1 - 2.5e-05 24.6 24.6 3.9 7.9 0.2 8.4 1 1 6 8 8 8 8 Clip-domain serine protease homolog masquerade Keratin_B2_2 PF13885.6 RUS87337.1 - 0.003 17.5 42.1 3.3 7.7 12.4 3.6 1 1 1 2 2 2 1 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 RUS87337.1 - 3.3 7.7 29.1 7.5 6.5 12.9 2.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein DUF3674 PF12426.8 RUS87337.1 - 8.2 6.6 10.0 23 5.1 0.1 4.0 1 1 0 3 3 3 0 RNA dependent RNA polymerase ALMT PF11744.8 RUS87338.1 - 0.21 10.4 4.3 0.3 9.9 4.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.32 RUS87339.1 - 1.5e-39 133.3 23.6 8.1e-07 29.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS87339.1 - 1.9e-14 53.7 0.1 0.018 15.4 0.1 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS87339.1 - 2.8e-05 24.1 0.0 0.37 10.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RUS87339.1 - 0.00028 20.3 0.0 0.027 13.8 0.0 2.7 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 RUS87339.1 - 0.012 14.6 1.3 27 3.6 0.1 4.0 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RUS87339.1 - 0.17 10.4 0.0 0.52 8.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain YabA PF06156.13 RUS87340.1 - 0.091 13.4 24.7 0.24 12.1 0.6 4.1 2 2 0 3 3 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 RUS87340.1 - 0.82 9.7 6.3 12 5.9 0.5 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1192 PF06698.11 RUS87340.1 - 3.5 7.7 13.7 17 5.6 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 RUS87340.1 - 9.9 6.2 9.6 20 5.3 4.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS87341.1 - 0.00043 19.3 89.3 0.00053 19.0 21.0 4.2 1 1 3 4 4 4 3 Spc7 kinetochore protein YabA PF06156.13 RUS87341.1 - 0.0021 18.7 6.4 0.0021 18.7 6.4 7.0 1 1 5 6 6 6 2 Initiation control protein YabA GAS PF13851.6 RUS87341.1 - 0.0068 15.8 21.7 0.0068 15.8 21.7 5.3 1 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 RUS87341.1 - 1.7 9.2 27.4 1.4 9.5 0.9 5.6 4 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 RUS87341.1 - 9.4 6.2 54.0 0.25 11.4 11.1 5.4 1 1 5 6 6 6 0 Laminin Domain II UCH PF00443.29 RUS87343.1 - 1.2e-38 133.1 0.0 3.4e-37 128.3 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS87343.1 - 5.3e-25 88.7 0.3 2.4e-20 73.4 0.0 3.0 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase V_ATPase_I PF01496.19 RUS87344.1 - 0.12 10.3 7.2 0.19 9.6 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-K PF11802.8 RUS87344.1 - 9 5.8 11.7 0.53 9.8 6.4 1.5 2 0 0 2 2 2 0 Centromere-associated protein K Ldl_recept_a PF00057.18 RUS87345.1 - 2.8e-109 357.0 235.8 9.4e-12 45.0 15.2 12.2 12 0 0 12 12 12 12 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 RUS87345.1 - 4.2e-06 27.3 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS87345.1 - 0.0025 17.9 0.0 0.01 16.0 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS87345.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 RUS87345.1 - 0.046 13.8 0.0 0.34 11.0 0.0 2.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain Ldl_recept_a PF00057.18 RUS87347.1 - 1.3e-24 86.0 33.2 3.6e-12 46.3 14.3 2.0 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A hEGF PF12661.7 RUS87347.1 - 1.2 9.9 11.5 23 5.8 0.1 4.1 2 2 2 4 4 4 0 Human growth factor-like EGF Laminin_B PF00052.18 RUS87348.1 - 1.9e-96 319.2 0.0 2.9e-33 114.6 0.0 3.2 3 0 0 3 3 3 3 Laminin B (Domain IV) Laminin_EGF PF00053.24 RUS87348.1 - 9.2e-74 243.4 196.6 1.4e-10 41.1 17.4 12.5 12 0 0 12 12 12 11 Laminin EGF domain I-set PF07679.16 RUS87348.1 - 1.6e-25 89.0 0.0 1.9e-11 43.9 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS87348.1 - 6.8e-24 84.3 0.9 5.9e-12 46.0 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 RUS87348.1 - 1.3e-14 54.2 0.3 2.8e-06 27.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS87348.1 - 3.2e-13 49.7 0.0 3.7e-05 23.8 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ldl_recept_a PF00057.18 RUS87348.1 - 9.5e-11 41.7 13.4 9.5e-11 41.7 13.4 5.2 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A V-set PF07686.17 RUS87348.1 - 3.7e-10 39.9 0.1 0.0014 18.8 0.2 3.6 2 1 1 3 3 3 2 Immunoglobulin V-set domain DNA_ligase_IV PF11411.8 RUS87348.1 - 0.17 12.0 0.1 0.95 9.6 0.2 2.1 2 0 0 2 2 2 0 DNA ligase IV Ig_3 PF13927.6 RUS87349.1 - 8.9e-57 189.6 0.3 4.6e-15 56.0 0.1 4.2 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS87349.1 - 3.3e-48 161.7 0.0 4.8e-14 52.2 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS87349.1 - 5.3e-40 135.6 0.2 5.9e-09 36.2 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS87349.1 - 8.6e-33 112.4 0.0 1.7e-08 34.5 0.0 4.8 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 RUS87349.1 - 4.5e-21 75.1 6.8 0.0017 18.5 0.1 7.4 4 4 3 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS87349.1 - 1.2e-14 53.6 0.0 0.029 13.9 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 RUS87349.1 - 6.3e-08 32.9 0.0 1.3 9.5 0.0 4.3 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 RUS87349.1 - 1.6e-07 31.3 0.4 0.1 12.7 0.0 3.9 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS87349.1 - 0.0001 22.3 0.0 4.7 7.3 0.0 4.2 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain zf-RRN7 PF11781.8 RUS87349.1 - 0.13 12.0 0.4 27 4.6 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Laminin_G_2 PF02210.24 RUS87350.1 - 2e-42 144.7 0.2 1.1e-17 64.7 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 RUS87350.1 - 8.9e-42 142.4 0.0 2.4e-20 73.1 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Ig_3 PF13927.6 RUS87350.1 - 3.6e-30 104.4 0.5 2.3e-10 40.9 0.0 3.8 4 0 0 4 4 3 3 Immunoglobulin domain I-set PF07679.16 RUS87350.1 - 4.9e-30 103.4 0.0 7.6e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS87350.1 - 2.4e-25 88.7 0.1 1.3e-08 35.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS87350.1 - 7.3e-21 74.1 0.0 2.7e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain EGF PF00008.27 RUS87350.1 - 2.5e-17 62.9 53.2 3.4e-08 33.6 7.7 5.0 5 0 0 5 5 4 4 EGF-like domain V-set PF07686.17 RUS87350.1 - 4.1e-16 59.1 1.6 0.0083 16.3 0.0 5.5 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS87350.1 - 1.3e-08 35.1 0.0 0.0044 17.4 0.0 3.7 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Laminin_G_3 PF13385.6 RUS87350.1 - 5.6e-08 33.1 0.2 0.0074 16.4 0.1 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Ig_6 PF18452.1 RUS87350.1 - 1.1e-06 28.1 0.0 0.095 12.3 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 RUS87350.1 - 2.8e-06 27.5 0.0 0.27 11.5 0.0 3.4 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain hEGF PF12661.7 RUS87350.1 - 2.4e-05 24.8 41.7 0.0006 20.3 1.6 5.5 5 0 0 5 5 4 3 Human growth factor-like EGF Izumo-Ig PF16706.5 RUS87350.1 - 4e-05 23.6 0.0 0.45 10.6 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 RUS87350.1 - 0.00084 19.5 0.0 4 7.7 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin C2-set domain Laminin_G_2 PF02210.24 RUS87351.1 - 5.1e-14 52.9 0.0 5.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 RUS87351.1 - 7.8e-13 48.8 0.0 8.7e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Laminin G domain Lipocalin PF00061.23 RUS87352.1 - 3.9e-06 27.1 1.2 4.7e-06 26.9 1.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS87352.1 - 5.4e-06 26.3 0.3 8.5e-06 25.7 0.3 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PepSY_2 PF13670.6 RUS87352.1 - 0.026 14.5 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Lipocalin PF00061.23 RUS87354.1 - 0.029 14.6 0.3 0.037 14.2 0.3 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_C25_C PF03785.14 RUS87354.1 - 0.079 12.8 0.1 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Lipocalin_7 PF14651.6 RUS87354.1 - 0.098 12.6 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family TPPK_C PF12555.8 RUS87355.1 - 0.28 11.3 3.3 0.49 10.5 3.3 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal GlnD_UR_UTase PF08335.11 RUS87355.1 - 2.4 8.3 0.0 2.4 8.3 0.0 2.7 4 0 0 4 4 4 0 GlnD PII-uridylyltransferase Glyco_transf_10 PF00852.19 RUS87357.1 - 3.7e-49 166.8 0.1 5e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS87357.1 - 1.8e-15 57.3 0.5 3.4e-15 56.4 0.2 1.7 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Lipocalin_7 PF14651.6 RUS87358.1 - 0.0066 16.4 0.1 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 RUS87359.1 - 0.0056 16.6 0.2 0.007 16.3 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SSF PF00474.17 RUS87360.1 - 5.4e-41 140.8 23.5 7.4e-41 140.3 23.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF485 PF04341.12 RUS87360.1 - 0.26 11.3 0.1 0.26 11.3 0.1 4.2 4 1 0 4 4 4 0 Protein of unknown function, DUF485 Multi_Drug_Res PF00893.19 RUS87360.1 - 6.6 7.5 17.7 1.8 9.3 0.5 3.6 3 1 0 3 3 3 0 Small Multidrug Resistance protein DUF957 PF06117.11 RUS87361.1 - 1.1e-08 34.4 0.1 0.88 9.2 0.0 5.6 2 1 4 6 6 6 4 Enterobacterial protein of unknown function (DUF957) FRB_dom PF08771.11 RUS87361.1 - 1.3e-07 32.0 4.1 2.8 8.4 0.1 6.3 1 1 6 7 7 7 1 FKBP12-rapamycin binding domain UL17 PF17640.2 RUS87361.1 - 0.014 15.4 4.9 4.8 7.2 0.0 4.6 3 2 2 5 5 5 0 Uncharacterized UL17 DUF1732 PF08340.11 RUS87361.1 - 0.022 14.7 0.3 1.1 9.2 0.1 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF1732) DUF1910 PF08928.10 RUS87361.1 - 0.16 12.0 5.4 48 4.0 0.1 4.7 3 2 2 5 5 5 0 Domain of unknown function (DUF1910) FANC_SAP PF18081.1 RUS87361.1 - 0.32 11.2 10.1 2.5 8.3 0.1 4.3 4 0 0 4 4 4 0 Fanconi anemia-associated nuclease SAP domain IIGP PF05049.13 RUS87361.1 - 2.4 7.1 7.6 7.1 5.6 0.3 3.0 1 1 2 3 3 3 0 Interferon-inducible GTPase (IIGP) CSRNP_N PF16019.5 RUS87362.1 - 0.1 12.5 0.7 0.14 12.0 0.7 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ig_3 PF13927.6 RUS87363.1 - 2.4 8.8 5.3 2 9.1 0.6 2.8 2 2 0 2 2 2 0 Immunoglobulin domain AGO_N PF18236.1 RUS87364.1 - 0.0011 19.2 0.1 13 6.0 0.0 3.9 1 1 4 5 5 5 2 Argonaute N domain PEP-utilizers PF00391.23 RUS87364.1 - 0.13 12.0 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain DUF1929 PF09118.11 RUS87364.1 - 0.71 10.2 14.2 36 4.7 0.1 5.4 1 1 5 6 6 6 0 Domain of unknown function (DUF1929) MTS PF05175.14 RUS87364.1 - 1 8.9 2.6 13 5.3 0.0 3.4 1 1 3 5 5 5 0 Methyltransferase small domain TBCC PF07986.12 RUS87366.1 - 8.3e-38 128.8 6.4 1.2e-37 128.2 6.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 RUS87366.1 - 0.00011 21.8 1.0 0.00017 21.2 1.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF1482 PF07358.11 RUS87366.1 - 0.029 14.3 0.9 0.062 13.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) YTH PF04146.15 RUS87367.1 - 4.9e-16 59.1 0.1 8.6e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 YT521-B-like domain RlaP PF10127.9 RUS87367.1 - 2.3e-14 53.6 0.0 4.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 RUS87367.1 - 0.00042 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 RUS87367.1 - 0.00056 20.0 0.0 0.0025 17.8 0.0 2.0 1 1 1 2 2 2 1 Polymerase beta, Nucleotidyltransferase zf-C3HC4_2 PF13923.6 RUS87367.1 - 0.62 10.0 4.9 0.17 11.7 1.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-A20 PF01754.16 RUS87367.1 - 1.6 8.7 4.9 35 4.5 1.2 3.2 3 0 0 3 3 3 0 A20-like zinc finger OTU PF02338.19 RUS87369.1 - 7.8e-10 39.3 0.0 2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease GST_C_3 PF14497.6 RUS87370.1 - 4.8e-17 62.0 0.5 7.5e-17 61.4 0.5 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS87370.1 - 4e-06 26.9 0.1 6.3e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS87370.1 - 2.4e-05 24.6 0.1 0.00021 21.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS87370.1 - 0.013 15.5 0.0 0.11 12.5 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS87370.1 - 0.035 14.5 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RT_RNaseH PF17917.1 RUS87372.1 - 2.2e-24 85.8 0.0 1.1e-23 83.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS87372.1 - 2e-21 76.4 0.0 6.2e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS87372.1 - 9.2e-18 64.1 0.1 2.1e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 RUS87372.1 - 2e-15 56.6 0.0 2e-14 53.5 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 RUS87372.1 - 0.00011 21.9 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS87372.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger FAP PF07174.11 RUS87372.1 - 2 7.8 13.0 4 6.8 13.0 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Retrotrans_gag PF03732.17 RUS87373.1 - 0.021 15.1 0.1 0.076 13.3 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein GST_C_3 PF14497.6 RUS87374.1 - 2.5e-14 53.2 0.0 4.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS87374.1 - 5.4e-08 32.9 0.0 8.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS87375.1 - 9.9e-15 54.6 0.0 2.1e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS87375.1 - 5.8e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS87375.1 - 6.9e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain fn3 PF00041.21 RUS87376.1 - 5.2e-22 78.0 4.3 4e-13 49.5 0.2 3.1 3 0 0 3 3 3 2 Fibronectin type III domain DUF2559 PF10832.8 RUS87376.1 - 0.18 11.9 0.6 0.36 10.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) fn3 PF00041.21 RUS87377.1 - 7.6e-24 83.9 3.1 2e-13 50.5 0.1 2.7 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS87377.1 - 5e-05 23.8 0.3 0.003 18.1 0.0 3.1 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 RUS87377.1 - 0.0028 17.9 0.1 0.17 12.1 0.1 2.4 2 0 0 2 2 2 1 SusE outer membrane protein bZIP_2 PF07716.15 RUS87378.1 - 4.9e-11 42.5 12.4 4.9e-11 42.5 12.4 3.4 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS87378.1 - 0.022 14.8 10.1 0.022 14.8 10.1 3.0 3 0 0 3 3 3 0 bZIP transcription factor Dapper PF15268.6 RUS87378.1 - 1.2 7.9 31.5 1.8 7.3 31.5 1.2 1 0 0 1 1 1 0 Dapper G-alpha PF00503.20 RUS87379.1 - 2.4e-122 408.5 1.2 2.8e-122 408.3 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS87379.1 - 1.2e-17 63.9 0.4 9.2e-13 48.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS87379.1 - 8.3e-06 25.3 2.5 0.0022 17.4 0.6 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RUS87379.1 - 0.00045 20.4 1.0 1.1 9.5 0.1 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RUS87379.1 - 0.013 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 RUS87379.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 RUS87379.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 RUS87379.1 - 0.17 11.4 1.8 7.4 6.1 0.6 2.4 2 0 0 2 2 2 0 Ras family Neur_chan_LBD PF02931.23 RUS87381.1 - 1e-44 152.6 2.5 1.7e-44 151.9 2.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS87381.1 - 4.9e-23 82.4 0.9 4.9e-23 82.4 0.9 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2254 PF10011.9 RUS87381.1 - 0.019 13.8 0.1 0.045 12.6 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Cytochrom_B558a PF05038.13 RUS87381.1 - 0.19 11.3 0.9 0.32 10.6 0.3 1.6 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Neur_chan_LBD PF02931.23 RUS87382.1 - 6.5e-44 150.0 2.4 8.9e-44 149.5 2.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS87382.1 - 1.1e-24 87.9 2.7 1.4e-22 80.9 0.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mpv17_PMP22 PF04117.12 RUS87384.1 - 7e-26 90.2 0.2 1.1e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4750 PF15938.5 RUS87384.1 - 0.0098 15.5 1.2 1.9 8.2 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4750) WD40 PF00400.32 RUS87385.1 - 1.6e-21 76.2 6.3 0.0044 17.8 0.7 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 RUS87385.1 - 2.4e-14 53.4 6.2 5.1e-14 52.3 6.2 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 RUS87385.1 - 2.9e-09 37.1 0.4 0.087 13.1 0.0 5.0 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS87385.1 - 4.2e-06 26.8 0.4 0.0094 15.9 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RUS87385.1 - 0.016 13.9 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Orf78 PF06024.12 RUS87386.1 - 0.0017 18.7 1.2 0.0053 17.0 1.2 1.8 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 RUS87386.1 - 0.005 16.8 0.1 0.005 16.8 0.1 2.4 2 0 0 2 2 2 1 Rifin Adeno_E3_14_5 PF04834.12 RUS87386.1 - 0.064 13.8 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Pox_EPC_I2-L1 PF12575.8 RUS87386.1 - 0.099 12.9 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DDHD PF02862.17 RUS87386.1 - 0.17 12.0 4.7 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 DDHD domain ShK PF01549.24 RUS87386.1 - 2.6 8.7 69.4 0.31 11.6 3.1 7.0 4 1 2 6 6 6 0 ShK domain-like Fmp27_WPPW PF10359.9 RUS87387.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FAM199X PF15814.5 RUS87387.1 - 0.23 10.5 18.9 0.3 10.1 18.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Herpes_capsid PF06112.11 RUS87387.1 - 0.51 10.4 27.9 0.8 9.7 27.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.9 RUS87387.1 - 5.1 5.5 12.1 5.5 5.4 12.1 1.0 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 RUS87387.1 - 5.5 6.5 24.7 6.1 6.3 24.7 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC106 PF15794.5 RUS87387.1 - 6 6.5 6.8 10 5.7 6.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Apt1 PF10351.9 RUS87387.1 - 9.2 5.0 9.3 9.4 5.0 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain rpo132 PF12415.8 RUS87389.1 - 0.019 14.2 0.2 8.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase GILT PF03227.16 RUS87390.1 - 2.4e-34 117.8 2.5 2.4e-34 117.8 2.5 2.1 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SapA PF02199.15 RUS87390.1 - 1.5e-05 25.1 5.6 1.7e-05 25.0 3.1 2.3 2 0 0 2 2 2 1 Saposin A-type domain Thioredoxin_4 PF13462.6 RUS87390.1 - 0.021 15.0 0.6 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Corona_NS2 PF04753.12 RUS87390.1 - 0.099 13.2 1.1 0.21 12.2 1.1 1.5 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 TMEM82 PF15816.5 RUS87390.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 PFK PF00365.20 RUS87391.1 - 4.7e-189 626.6 2.6 2.7e-107 358.4 1.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyco_transf_7N PF13733.6 RUS87392.1 - 1.8e-46 157.1 0.0 1.8e-46 157.1 0.0 2.1 2 0 0 2 2 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS87392.1 - 2.8e-27 94.2 0.4 5.6e-27 93.2 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DDHD PF02862.17 RUS87392.1 - 0.00058 20.1 1.8 0.00091 19.4 1.8 1.3 1 0 0 1 1 1 1 DDHD domain EPL1 PF10513.9 RUS87392.1 - 0.013 15.9 10.2 0.013 15.9 10.2 1.6 2 0 0 2 2 1 0 Enhancer of polycomb-like SID-1_RNA_chan PF13965.6 RUS87392.1 - 0.019 13.4 1.7 0.029 12.8 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glycos_transf_2 PF00535.26 RUS87392.1 - 0.03 14.1 0.3 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Spore_coat_CotO PF14153.6 RUS87392.1 - 0.035 14.1 24.6 0.057 13.3 24.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Spt20 PF12090.8 RUS87392.1 - 0.044 13.4 27.4 0.07 12.7 27.4 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 RUS87392.1 - 0.12 11.0 6.2 0.21 10.3 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSF100_C PF13299.6 RUS87392.1 - 0.14 12.3 11.2 0.27 11.4 11.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 RUS87392.1 - 0.26 10.2 2.8 0.41 9.5 2.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 RUS87392.1 - 0.26 10.7 13.7 0.38 10.2 13.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3408 PF11888.8 RUS87392.1 - 0.32 11.1 15.7 0.87 9.7 15.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PAT1 PF09770.9 RUS87392.1 - 0.43 8.8 20.2 0.56 8.4 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 RUS87392.1 - 0.59 9.5 8.2 1 8.7 8.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 RUS87392.1 - 0.75 9.6 19.3 1.1 9.0 19.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Otopetrin PF03189.13 RUS87392.1 - 0.81 8.4 6.9 1.4 7.7 6.9 1.3 1 0 0 1 1 1 0 Otopetrin BORG_CEP PF14957.6 RUS87392.1 - 1.1 10.5 8.5 1.8 9.7 8.5 1.5 1 0 0 1 1 1 0 Cdc42 effector SIT PF15330.6 RUS87392.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.7 2 1 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT RNA_pol_Rpc4 PF05132.14 RUS87392.1 - 1.3 9.4 13.9 2.3 8.6 13.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 RUS87392.1 - 1.6 8.9 13.6 2.5 8.3 13.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Endostatin PF06482.11 RUS87392.1 - 1.6 8.1 12.8 2.5 7.5 12.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1387 PF07139.11 RUS87392.1 - 2 8.1 19.2 3 7.5 19.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 RUS87392.1 - 2.1 7.0 17.7 3.6 6.3 17.7 1.3 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 RUS87392.1 - 2.1 8.4 11.4 3.6 7.6 11.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region SLC12 PF03522.15 RUS87392.1 - 2.3 7.1 13.5 4.2 6.3 13.5 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Paf1 PF03985.13 RUS87392.1 - 2.4 7.1 23.9 3.4 6.6 23.9 1.2 1 0 0 1 1 1 0 Paf1 MMR1 PF08505.10 RUS87392.1 - 2.5 8.3 17.6 0.42 10.9 14.0 1.5 2 0 0 2 2 1 0 Mitochondrial Myo2 receptor-related protein CobT PF06213.12 RUS87392.1 - 2.6 7.4 25.5 4 6.7 25.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Suf PF05843.14 RUS87392.1 - 2.7 7.9 17.7 4.7 7.1 17.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 RUS87392.1 - 3 6.7 9.6 4.3 6.2 9.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 RUS87392.1 - 3.2 4.7 13.1 4.1 4.4 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 RUS87392.1 - 4.1 6.1 9.5 5.8 5.6 9.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PepSY_TM PF03929.16 RUS87392.1 - 5.7 6.5 5.6 7.5 6.1 3.4 1.9 2 0 0 2 2 2 0 PepSY-associated TM region CDC45 PF02724.14 RUS87392.1 - 5.9 5.1 18.5 8.4 4.5 18.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BBL5 PF07289.11 RUS87392.1 - 6.2 5.8 10.0 10 5.0 10.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein LMBR1 PF04791.16 RUS87392.1 - 7.4 5.3 6.4 12 4.7 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NPR3 PF03666.13 RUS87392.1 - 7.6 5.2 14.5 12 4.6 14.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 RUS87392.1 - 7.6 5.5 9.4 14 4.6 9.4 1.4 1 0 0 1 1 1 0 CLN3 protein Tim54 PF11711.8 RUS87392.1 - 8.3 5.1 17.6 14 4.3 17.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LRR_4 PF12799.7 RUS87393.1 - 1.6e-35 120.5 65.2 6.5e-08 32.8 2.1 7.2 2 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS87393.1 - 3.3e-24 84.4 36.4 1.4e-07 31.2 5.5 5.7 1 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 RUS87393.1 - 2.2e-22 79.4 6.5 6.7e-10 38.7 0.1 3.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 RUS87393.1 - 2.2e-10 39.7 28.0 0.017 15.1 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 RUS87393.1 - 0.00026 21.1 30.3 2 9.3 0.2 8.8 6 3 0 6 6 6 2 Leucine Rich Repeat COesterase PF00135.28 RUS87396.1 - 9e-148 493.3 0.0 1.1e-147 493.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS87396.1 - 1.1e-09 38.5 0.1 3.8e-09 36.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold BTG PF07742.12 RUS87397.1 - 7e-37 125.8 0.0 1.6e-36 124.7 0.0 1.6 2 0 0 2 2 2 1 BTG family RFX5_N PF18326.1 RUS87399.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 RFX5 N-terminal domain Peptidase_Mx1 PF15890.5 RUS87399.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase DNA_ligase_A_M PF01068.21 RUS87400.1 - 3.3e-66 222.8 0.3 7.9e-66 221.6 0.3 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RUS87400.1 - 8.2e-44 150.0 0.1 2.8e-43 148.2 0.1 2.0 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 RUS87400.1 - 3.1e-26 91.8 2.6 5.8e-26 91.0 0.0 2.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Presenilin PF01080.17 RUS87400.1 - 0.0033 16.3 4.0 0.0033 16.3 4.0 4.2 2 1 2 4 4 4 1 Presenilin DNA_ligase_OB_2 PF14743.6 RUS87400.1 - 0.0084 16.1 0.7 3.8 7.6 0.1 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain C1q PF00386.21 RUS87401.1 - 2.4e-24 86.0 0.1 2.7e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 RUS87401.1 - 1.1e-08 34.6 24.6 1.7e-08 34.1 24.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 RUS87401.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain DNA_pol_phi PF04931.13 RUS87404.1 - 0.057 11.5 26.1 0.088 10.9 26.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RUS87404.1 - 0.077 12.4 7.0 0.11 11.8 7.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 RUS87404.1 - 0.12 12.2 10.9 0.18 11.7 10.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 RUS87404.1 - 0.34 8.9 3.5 0.49 8.4 3.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mpp10 PF04006.12 RUS87404.1 - 0.49 8.8 8.5 0.65 8.4 8.5 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS87404.1 - 1.4 7.0 16.8 2 6.6 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS87404.1 - 3.2 5.9 15.9 4.4 5.5 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein LHC PF00556.20 RUS87404.1 - 3.5 7.9 5.9 1.3e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 Antenna complex alpha/beta subunit Kazal_1 PF00050.21 RUS87406.1 - 2.2e-10 40.4 9.5 8.8e-10 38.5 4.8 2.5 1 1 2 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RUS87406.1 - 4.6e-08 33.0 5.9 3.1e-07 30.4 1.2 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 RUS87407.1 - 2.5e-19 69.1 22.3 7.9e-07 29.1 4.1 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 RUS87407.1 - 2.5e-18 65.8 19.7 2.4e-07 30.7 2.9 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain PA26 PF04636.13 RUS87408.1 - 0.067 12.1 1.6 0.098 11.6 1.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RWD PF05773.22 RUS87410.1 - 1.2e-09 38.5 0.2 2e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 RUS87410.1 - 0.009 16.1 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DDE_Tnp_1_7 PF13843.6 RUS87411.1 - 2.7e-06 26.9 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 DDE_1 PF03184.19 RUS87413.1 - 3.6e-14 52.8 0.0 5.6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 RUS87413.1 - 0.0013 18.5 0.5 0.0027 17.5 0.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease GAS PF13851.6 RUS87413.1 - 0.003 17.0 9.5 0.003 17.0 9.5 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1640 PF07798.11 RUS87413.1 - 0.034 14.2 9.9 0.071 13.2 9.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Tropomyosin_1 PF12718.7 RUS87413.1 - 0.066 13.4 20.2 0.072 13.2 9.0 2.4 1 1 1 2 2 2 0 Tropomyosin like DUF5082 PF16888.5 RUS87413.1 - 0.11 12.7 9.8 0.19 12.0 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Bap31_Bap29_C PF18035.1 RUS87413.1 - 0.13 12.3 17.5 0.14 12.2 3.5 2.9 3 0 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain She9_MDM33 PF05546.11 RUS87413.1 - 0.2 11.4 7.5 0.35 10.6 7.5 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family LMBR1 PF04791.16 RUS87413.1 - 0.29 10.0 0.8 0.38 9.6 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 RUS87413.1 - 0.3 10.4 2.6 0.47 9.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 RUS87413.1 - 0.32 11.3 12.7 0.42 10.9 2.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.12 RUS87413.1 - 0.33 11.0 4.4 0.82 9.7 0.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 RUS87413.1 - 0.5 10.5 11.7 4.4 7.5 11.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RUS87413.1 - 0.6 8.9 14.7 0.9 8.4 14.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 RUS87413.1 - 0.67 10.0 20.7 0.52 10.3 6.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 RUS87413.1 - 0.84 9.7 15.2 18 5.4 14.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 RUS87413.1 - 0.85 9.9 7.3 0.85 9.9 0.5 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex OmpH PF03938.14 RUS87413.1 - 0.95 9.8 7.7 2.6 8.4 7.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PhaP_Bmeg PF09602.10 RUS87413.1 - 1.5 8.7 12.8 0.41 10.6 4.3 2.2 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2203 PF09969.9 RUS87413.1 - 1.6 9.5 6.3 0.86 10.3 2.6 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lectin_N PF03954.14 RUS87413.1 - 1.6 8.5 8.7 0.25 11.1 1.6 2.3 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain bZIP_2 PF07716.15 RUS87413.1 - 1.9 8.6 9.8 5.9 7.1 1.3 2.7 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.8 RUS87413.1 - 2.7 8.1 13.5 5 7.2 13.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CDC37_N PF03234.14 RUS87413.1 - 3.2 8.7 8.8 0.67 10.9 3.8 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding FapA PF03961.13 RUS87413.1 - 4 5.9 12.2 4.7 5.7 3.7 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4446 PF14584.6 RUS87413.1 - 4.9 7.1 10.6 7.4 6.5 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ATG16 PF08614.11 RUS87413.1 - 6.5 6.9 13.6 9.9 6.3 3.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 RUS87413.1 - 7.2 6.9 16.1 6.4 7.1 7.0 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 RUS87413.1 - 7.4 6.7 18.2 3.4 7.8 5.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 RUS87413.1 - 7.5 7.0 7.5 6.4 7.2 0.5 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 RUS87413.1 - 8.3 6.3 15.1 1.2 9.1 5.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain HSCB_C PF07743.13 RUS87413.1 - 8.6 6.9 9.9 2.3 8.7 3.3 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Cep57_CLD_2 PF14197.6 RUS87413.1 - 9 6.5 12.3 8.9 6.5 1.2 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CSRNP_N PF16019.5 RUS87414.1 - 0.14 12.1 0.4 0.25 11.2 0.4 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pep1_7 PF17232.2 RUS87414.1 - 0.46 11.0 6.1 0.1 13.1 1.8 2.1 2 0 0 2 2 2 0 Elicitor peptide 1-7 Nucleos_tra2_N PF01773.20 RUS87415.1 - 5.8 7.6 17.3 71 4.1 0.5 3.8 1 1 1 2 2 2 0 Na+ dependent nucleoside transporter N-terminus DPM2 PF07297.12 RUS87416.1 - 1.4e-27 95.8 3.8 1.5e-27 95.7 3.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2062 PF09835.9 RUS87416.1 - 1.7 8.5 7.9 0.42 10.4 0.5 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) SURF4 PF02077.15 RUS87417.1 - 1.6e-122 408.3 6.2 1.8e-122 408.1 6.2 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 RUS87417.1 - 6.6e-20 71.8 0.0 8.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF4808 PF16066.5 RUS87417.1 - 0.02 15.4 0.3 0.038 14.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Arf PF00025.21 RUS87418.1 - 1.9e-69 232.6 0.0 2.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS87418.1 - 5.3e-14 52.5 0.0 7.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS87418.1 - 2e-13 50.2 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS87418.1 - 2.2e-13 50.1 0.0 2.6e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS87418.1 - 3e-13 49.6 0.0 4.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS87418.1 - 3.2e-13 49.6 0.5 2.1e-09 37.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 RUS87418.1 - 1.6e-07 31.4 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS87418.1 - 1.1e-05 25.1 0.0 0.00013 21.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 RUS87418.1 - 0.0004 20.8 0.0 0.00056 20.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RUS87418.1 - 0.015 15.8 0.0 0.026 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RUS87418.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 RUS87418.1 - 0.084 11.8 0.1 0.84 8.6 0.1 2.2 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RUS87418.1 - 0.084 13.4 0.2 0.13 12.8 0.2 1.6 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 RUS87418.1 - 0.12 11.9 0.2 0.42 10.1 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PhyH PF05721.13 RUS87419.1 - 1.3e-16 61.5 0.0 1.3e-15 58.2 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 RUS87419.1 - 0.023 15.6 0.0 0.048 14.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PAX PF00292.18 RUS87420.1 - 1.7e-27 95.8 0.0 3.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 RUS87420.1 - 6.5e-23 80.3 1.3 1.3e-22 79.4 1.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS87420.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Coatomer_E PF04733.14 RUS87421.1 - 2.7e-101 338.8 4.2 3.1e-101 338.6 4.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 RUS87421.1 - 2.7e-12 47.0 5.2 2.1e-06 28.1 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS87421.1 - 2.8e-09 37.0 2.4 0.00053 20.1 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS87421.1 - 8.1e-07 29.4 1.8 0.2 12.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RUS87421.1 - 8.2e-07 28.7 1.2 0.00053 19.9 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS87421.1 - 1.9e-06 28.0 0.7 0.0046 17.2 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS87421.1 - 9.2e-05 22.1 1.4 0.0016 18.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS87421.1 - 0.0001 22.1 1.8 0.01 15.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 RUS87421.1 - 0.0038 16.9 3.0 0.037 13.7 1.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain Com_YlbF PF06133.11 RUS87421.1 - 0.0039 17.8 1.9 0.0082 16.7 0.1 2.5 3 1 0 3 3 3 1 Control of competence regulator ComK, YlbF/YmcA SRP_TPR_like PF17004.5 RUS87421.1 - 0.0046 17.0 3.3 0.59 10.2 0.6 2.4 1 1 1 2 2 2 2 Putative TPR-like repeat TPR_16 PF13432.6 RUS87421.1 - 0.0068 17.0 2.0 0.29 11.8 0.1 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS87421.1 - 0.007 16.0 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 RUS87421.1 - 0.02 15.5 5.3 4.6 8.1 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 RUS87421.1 - 0.023 15.3 0.2 3.6 8.5 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR PF01535.20 RUS87421.1 - 0.063 13.6 0.2 9.6 6.7 0.1 2.9 2 0 0 2 2 2 0 PPR repeat TPR_8 PF13181.6 RUS87421.1 - 0.094 13.0 3.0 12 6.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ibs_toxin PF13956.6 RUS87423.1 - 0.18 11.8 2.3 0.37 10.8 2.3 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system RNase_H PF00075.24 RUS87424.1 - 2.2e-10 40.9 2.6 6.6e-10 39.3 0.1 2.5 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS87424.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Pertussis_S2S3 PF02918.15 RUS87424.1 - 0.0075 16.2 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 Pertussis toxin, subunit 2 and 3, C-terminal domain DUF4864 PF16156.5 RUS87424.1 - 0.06 14.0 0.1 0.11 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) DUF1244 PF06844.11 RUS87424.1 - 0.2 11.8 1.0 0.53 10.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) F-actin_cap_A PF01267.17 RUS87425.1 - 1e-100 336.6 0.3 1.2e-100 336.4 0.3 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Nup35_RRM PF05172.13 RUS87425.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Arrestin_N PF00339.29 RUS87427.1 - 6.9e-21 74.8 0.0 1.1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS87427.1 - 3.7e-20 72.7 0.0 3.4e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain CaATP_NAI PF12515.8 RUS87427.1 - 0.0027 17.3 0.8 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Ca2+-ATPase N terminal autoinhibitory domain Rgp1 PF08737.10 RUS87427.1 - 0.025 13.8 0.0 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 Rgp1 Glyco_hydro_47 PF01532.20 RUS87428.1 - 1.5e-112 376.8 0.0 2.5e-112 376.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 CUB PF00431.20 RUS87429.1 - 1.9e-61 205.2 0.4 3.4e-25 88.5 0.0 4.5 4 0 0 4 4 4 3 CUB domain Trypsin PF00089.26 RUS87429.1 - 3.8e-54 183.8 0.0 1e-53 182.4 0.0 1.8 1 0 0 1 1 1 1 Trypsin I-set PF07679.16 RUS87429.1 - 3e-19 68.9 0.0 2e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS87429.1 - 3.2e-18 66.1 0.0 4.7e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS87429.1 - 8e-14 51.6 0.0 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS87429.1 - 2.3e-11 43.8 0.0 2.5e-06 27.7 0.0 2.6 1 1 1 2 2 2 2 Immunoglobulin domain EGF PF00008.27 RUS87429.1 - 3.2e-10 40.1 25.4 2.9e-06 27.5 8.4 3.6 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 RUS87429.1 - 3e-05 24.5 18.6 0.00027 21.4 8.9 4.5 2 1 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.13 RUS87429.1 - 7.8e-05 23.0 23.6 0.0013 19.0 9.5 3.3 2 0 0 2 2 2 2 EGF-like domain Ig_5 PF16681.5 RUS87429.1 - 0.0034 17.8 0.0 0.69 10.4 0.0 2.6 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CUB_2 PF02408.20 RUS87429.1 - 0.0081 15.9 2.6 0.086 12.6 0.3 3.3 3 1 0 3 3 3 1 CUB-like domain Ig_6 PF18452.1 RUS87429.1 - 0.01 15.4 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Trypsin_2 PF13365.6 RUS87429.1 - 0.019 15.9 0.0 0.054 14.4 0.0 1.8 1 0 0 1 1 1 0 Trypsin-like peptidase domain EGF_3 PF12947.7 RUS87429.1 - 0.05 13.8 8.5 0.46 10.7 1.3 3.3 2 0 0 2 2 2 0 EGF domain FXa_inhibition PF14670.6 RUS87429.1 - 0.25 11.7 15.6 1.2 9.5 3.2 3.3 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS87429.1 - 0.46 10.4 15.1 0.39 10.7 1.0 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like GRDP-like PF07173.12 RUS87430.1 - 3.5e-49 167.1 2.8 6.4e-38 130.6 0.3 3.2 1 1 2 3 3 3 3 Glycine-rich domain-containing protein-like ETC_C1_NDUFA5 PF04716.14 RUS87431.1 - 1.8e-24 85.3 0.1 2.5e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Kelch_6 PF13964.6 RUS87432.1 - 3.6e-25 87.4 7.7 0.00033 20.8 0.0 7.0 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 RUS87432.1 - 1.8e-21 75.6 10.6 1.5e-05 24.8 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RUS87432.1 - 3.7e-21 74.9 7.1 8.3e-07 29.2 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS87432.1 - 1.9e-20 72.6 11.5 5.4e-06 26.3 0.1 7.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS87432.1 - 3.6e-20 71.3 12.3 6.1e-06 25.7 0.6 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS87432.1 - 5.6e-08 32.5 11.3 0.015 15.2 0.1 5.8 6 1 0 6 6 6 2 Kelch motif RAG2 PF03089.14 RUS87432.1 - 0.0049 15.9 0.5 2 7.3 0.0 2.9 3 0 0 3 3 3 2 Recombination activating protein 2 cNMP_binding PF00027.29 RUS87434.1 - 1.8e-41 140.1 0.0 9.5e-20 70.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RUS87434.1 - 7.1e-12 44.8 0.1 1.3e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SpuA_C PF18033.1 RUS87434.1 - 0.11 12.5 0.3 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 SpuA C-terminal G-patch PF01585.23 RUS87435.1 - 3.7e-17 61.9 4.8 7.8e-17 60.9 4.8 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 RUS87435.1 - 3.8e-16 58.7 0.0 7.9e-07 28.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 RUS87435.1 - 2.8e-15 56.1 18.5 2.8e-15 56.1 18.5 2.5 2 0 0 2 2 2 1 OCRE domain G-patch_2 PF12656.7 RUS87435.1 - 8.9e-10 38.5 1.8 8.9e-10 38.5 1.8 2.0 2 0 0 2 2 2 1 G-patch domain RCDG1 PF15725.5 RUS87435.1 - 0.0086 16.5 4.3 0.023 15.1 4.3 1.7 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein zf-C2H2_11 PF16622.5 RUS87435.1 - 0.039 13.7 0.7 0.08 12.7 0.7 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type DnaJ-X PF14308.6 RUS87435.1 - 0.2 11.1 4.8 0.093 12.2 1.0 2.1 1 1 1 2 2 2 0 X-domain of DnaJ-containing RVT_1 PF00078.27 RUS87436.1 - 5.8e-44 150.2 0.5 7.2e-44 149.9 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP2C PF00481.21 RUS87438.1 - 7.1e-10 38.9 0.0 8.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C AAA_12 PF13087.6 RUS87439.1 - 7.4e-42 143.2 0.9 1.9e-41 141.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 RUS87439.1 - 2.1e-30 106.4 12.8 9.6e-15 55.1 0.3 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 RUS87439.1 - 1.5e-09 38.3 2.5 5.6e-08 33.3 2.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RUS87439.1 - 7.5e-08 32.3 2.5 0.00014 21.7 0.0 3.0 3 1 0 3 3 3 2 AAA domain ResIII PF04851.15 RUS87439.1 - 4.6e-05 23.5 0.2 0.00013 22.1 0.2 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RUS87439.1 - 5.8e-05 23.4 0.8 0.07 13.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain DEAD PF00270.29 RUS87439.1 - 8.5e-05 22.4 1.9 0.00075 19.3 0.1 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF2075 PF09848.9 RUS87439.1 - 0.00017 21.0 3.5 0.00054 19.3 0.2 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 RUS87439.1 - 0.012 15.1 0.6 0.033 13.6 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 RUS87439.1 - 0.019 15.4 4.5 1.3 9.4 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RUS87439.1 - 0.02 15.4 2.1 3.5 8.2 0.1 3.8 3 1 0 3 3 3 0 AAA domain DUF3848 PF12959.7 RUS87440.1 - 0.017 15.2 0.7 0.82 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) HSCB_C PF07743.13 RUS87440.1 - 0.06 13.8 2.8 9.8 6.8 0.1 2.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain ubiquitin PF00240.23 RUS87440.1 - 0.27 11.0 3.4 3.8 7.3 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin family CdvA PF18822.1 RUS87440.1 - 0.34 10.8 4.3 9.5 6.1 0.3 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF1192 PF06698.11 RUS87440.1 - 3.2 7.9 8.4 0.81 9.8 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Polysacc_deac_1 PF01522.21 RUS87441.1 - 4e-09 36.4 0.1 1e-08 35.1 0.1 1.8 2 1 0 2 2 2 1 Polysaccharide deacetylase DUF1180 PF06679.12 RUS87443.1 - 0.72 10.3 3.4 0.93 9.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-H2C2_2 PF13465.6 RUS87444.1 - 4.9e-36 121.6 70.3 2.1e-06 27.9 1.0 10.2 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS87444.1 - 3.8e-28 96.3 75.6 0.00017 21.8 2.9 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS87444.1 - 1.9e-27 93.5 74.6 0.0019 18.9 0.5 10.1 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.7 RUS87444.1 - 8.6e-09 35.5 45.2 0.0076 16.6 0.2 9.0 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS87444.1 - 1e-08 35.2 41.2 0.0086 16.3 0.2 9.7 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 RUS87444.1 - 0.0021 17.6 0.9 0.0021 17.6 0.9 5.6 3 2 2 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 RUS87444.1 - 0.0025 18.2 48.9 2.5 8.6 11.2 8.0 3 2 5 8 8 8 4 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 RUS87444.1 - 0.0041 17.2 34.1 0.24 11.6 1.4 7.1 5 4 1 6 6 6 3 Zinc ribbon domain zf-Di19 PF05605.12 RUS87444.1 - 0.0056 17.0 46.7 0.084 13.2 1.6 6.3 1 1 7 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 RUS87444.1 - 0.011 15.4 0.6 0.011 15.4 0.6 7.6 8 1 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RUS87444.1 - 0.014 15.6 5.8 0.014 15.6 5.8 4.8 1 1 6 7 7 7 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 RUS87444.1 - 0.025 14.5 2.9 0.025 14.5 2.9 8.7 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 RUS87444.1 - 0.046 13.5 49.7 0.67 9.8 0.7 8.6 9 0 0 9 9 8 0 zinc-finger C2H2-type Ta0938 PF11494.8 RUS87444.1 - 0.086 13.1 12.2 3.4 8.0 1.8 5.0 1 1 4 5 5 5 0 Ta0938 C1_2 PF03107.16 RUS87444.1 - 0.088 13.1 47.8 1.8 9.0 2.4 8.7 2 2 4 6 6 6 0 C1 domain zinc_ribbon_15 PF17032.5 RUS87444.1 - 0.28 11.9 32.5 0.74 10.6 2.1 5.3 1 1 4 6 6 5 0 zinc-ribbon family A2L_zn_ribbon PF08792.10 RUS87444.1 - 0.72 9.6 0.0 0.72 9.6 0.0 6.6 9 0 0 9 9 9 0 A2L zinc ribbon domain zf-FPG_IleRS PF06827.14 RUS87444.1 - 0.9 9.5 0.0 0.9 9.5 0.0 7.0 8 0 0 8 8 7 0 Zinc finger found in FPG and IleRS DUF3268 PF11672.8 RUS87444.1 - 1.3 9.4 23.4 0.97 9.8 0.3 5.0 5 0 0 5 5 5 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 RUS87444.1 - 3.6 8.0 46.8 8.3 6.8 1.5 7.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf_C2H2_13 PF18508.1 RUS87444.1 - 4.2 7.1 0.0 4.2 7.1 0.0 5.9 5 1 2 7 7 6 0 Zinc finger domain DUF3402 PF11882.8 RUS87445.1 - 3.2e-104 349.6 10.9 8.2e-67 226.3 1.5 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 RUS87445.1 - 3e-44 151.4 0.0 4.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein zf-CCHC PF00098.23 RUS87446.1 - 0.012 15.7 2.5 0.012 15.7 2.5 3.0 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 RUS87446.1 - 0.032 14.1 2.0 0.032 14.1 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 RUS87446.1 - 0.3 11.1 8.5 0.031 14.2 3.7 1.8 2 0 0 2 2 2 0 Zinc knuckle LCIB_C_CA PF18599.1 RUS87446.1 - 1.4 8.2 3.6 5.6 6.2 3.5 2.0 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases zf-CCHC_5 PF14787.6 RUS87446.1 - 8.8 6.1 20.4 0.099 12.4 5.7 2.8 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger ANF_receptor PF01094.28 RUS87448.1 - 6.3e-41 140.7 0.1 1e-40 139.9 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS87448.1 - 1e-32 113.5 0.1 2.1e-27 96.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 RUS87448.1 - 9.3e-29 100.6 0.0 2.5e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Dehydratase_hem PF13816.6 RUS87448.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Haem-containing dehydratase Kinesin PF00225.23 RUS87449.1 - 2.4e-110 368.6 1.0 2.4e-110 368.6 1.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS87449.1 - 3e-60 202.5 0.6 1.7e-58 196.8 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 RUS87449.1 - 1.1e-05 24.6 17.2 2.1e-05 23.6 17.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 RUS87449.1 - 0.00025 21.1 13.9 0.00025 21.1 13.9 3.6 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein HOOK PF05622.12 RUS87449.1 - 0.0095 14.1 26.5 0.019 13.1 26.5 1.4 1 0 0 1 1 1 1 HOOK protein DUF641 PF04859.12 RUS87449.1 - 0.012 15.9 26.4 0.43 10.9 6.7 4.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 RUS87449.1 - 0.018 15.1 39.1 0.019 15.1 21.7 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CAP59_mtransfer PF11735.8 RUS87449.1 - 0.029 14.0 2.2 0.081 12.6 2.2 1.8 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF3584 PF12128.8 RUS87449.1 - 0.3 8.5 24.0 0.51 7.8 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HMMR_N PF15905.5 RUS87449.1 - 0.53 9.7 35.7 0.039 13.4 20.2 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 RUS87449.1 - 0.78 8.6 35.5 0.015 14.2 28.0 1.9 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 RUS87449.1 - 1.1 9.3 18.2 0.84 9.7 6.7 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 RUS87449.1 - 1.3 9.2 22.3 6.1 7.0 3.5 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 RUS87449.1 - 2.4 8.2 39.7 1.5 8.9 31.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI_PP_I PF18363.1 RUS87449.1 - 6.9 6.9 6.8 11 6.3 1.0 2.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain AAA_16 PF13191.6 RUS87449.1 - 9.2 6.6 6.5 1.5 9.2 0.1 2.8 2 2 0 2 2 1 0 AAA ATPase domain Borrelia_P83 PF05262.11 RUS87449.1 - 9.5 4.6 30.6 7.9 4.8 24.0 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein MAPEG PF01124.18 RUS87450.1 - 0.00013 21.8 8.9 0.00046 20.1 2.0 2.0 1 1 1 2 2 2 2 MAPEG family DUF4386 PF14329.6 RUS87450.1 - 0.077 12.9 6.7 0.029 14.2 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) DUF4006 PF13179.6 RUS87450.1 - 0.94 9.4 5.4 0.74 9.8 0.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF4006) Med14 PF08638.11 RUS87451.1 - 1.9e-65 219.9 0.1 2.3e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit MED14 BIR PF00653.21 RUS87453.1 - 1.7e-14 54.2 1.2 1.7e-14 54.2 1.2 3.5 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS87453.1 - 1.9e-07 30.8 18.1 2.4e-07 30.5 15.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS87453.1 - 0.34 10.8 12.9 0.85 9.5 12.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Patched PF02460.18 RUS87455.1 - 3e-13 48.8 34.9 3e-11 42.2 14.8 2.5 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 RUS87455.1 - 1e-12 48.1 30.3 1.2e-12 47.9 9.8 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 RUS87455.1 - 0.00033 19.7 5.1 0.00033 19.7 5.1 2.8 2 1 0 2 2 2 1 MMPL family TFIIA PF03153.13 RUS87457.1 - 0.0037 17.3 22.6 0.0046 17.0 22.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RUS87457.1 - 1.9 6.5 38.7 2.6 6.1 38.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi YopH_N PF09013.10 RUS87457.1 - 3.2 8.1 4.8 33 4.8 0.0 3.9 2 1 4 6 6 6 0 YopH, N-terminal DUF2796 PF10986.8 RUS87457.1 - 7.4 6.5 7.7 14 5.6 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Arrestin_N PF00339.29 RUS87458.1 - 8.3e-28 97.3 0.1 9.2e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 RUS87458.1 - 0.091 11.7 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 RUS87458.1 - 0.58 9.3 2.2 1.6 7.8 0.8 2.0 1 1 0 2 2 2 0 Rgp1 Rhodanese_C PF12368.8 RUS87459.1 - 0.83 10.1 7.5 9.5 6.7 0.8 2.4 2 0 0 2 2 2 0 Rhodanase C-terminal Cadherin_3 PF16184.5 RUS87460.1 - 6.9e-187 608.8 51.4 2.6e-28 98.3 0.0 15.4 15 0 0 15 15 15 15 Cadherin-like Laminin_G_2 PF02210.24 RUS87460.1 - 5.9e-46 156.2 4.9 9.6e-22 77.9 0.1 5.1 5 0 0 5 5 5 2 Laminin G domain Laminin_G_1 PF00054.23 RUS87460.1 - 3.1e-40 137.4 5.6 4.1e-20 72.3 0.1 4.8 6 0 0 6 6 6 2 Laminin G domain Laminin_G_3 PF13385.6 RUS87460.1 - 5.8e-08 33.0 0.1 0.0095 16.1 0.0 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Cadherin_4 PF17803.1 RUS87460.1 - 0.0001 22.8 9.0 0.87 10.3 0.3 6.9 6 0 0 6 6 6 1 Bacterial cadherin-like domain TMEM154 PF15102.6 RUS87460.1 - 0.0002 21.3 0.3 0.00046 20.1 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 RUS87460.1 - 0.0024 17.9 0.1 0.0042 17.0 0.1 1.3 1 0 0 1 1 1 1 Rifin DUF3377 PF11857.8 RUS87460.1 - 0.0063 16.4 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Orf78 PF06024.12 RUS87460.1 - 0.0095 16.2 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) EphA2_TM PF14575.6 RUS87460.1 - 0.019 15.8 0.0 0.044 14.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 RUS87460.1 - 0.027 14.2 0.3 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 RUS87460.1 - 0.027 13.2 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 RUS87460.1 - 0.095 12.1 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Insulin_TMD PF17870.1 RUS87460.1 - 0.11 12.6 1.5 0.32 11.1 1.5 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF PF00008.27 RUS87460.1 - 0.17 12.2 2.4 0.31 11.4 2.4 1.4 1 0 0 1 1 1 0 EGF-like domain DUF1180 PF06679.12 RUS87460.1 - 0.2 12.0 5.3 0.2 12.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DZF PF07528.14 RUS87461.1 - 1.5e-79 267.1 0.0 2.6e-79 266.4 0.0 1.4 1 0 0 1 1 1 1 DZF domain zf-met PF12874.7 RUS87461.1 - 3.3e-22 78.1 15.4 7.8e-07 29.3 0.1 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS87461.1 - 1.8e-16 59.9 12.9 3.9e-06 27.0 1.8 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS87461.1 - 0.0025 18.1 18.2 0.57 10.5 1.2 4.2 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) DUF2428 PF10350.9 RUS87461.1 - 0.06 12.6 0.4 0.12 11.6 0.4 1.5 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) THOC2_N PF16134.5 RUS87461.1 - 0.066 11.8 0.6 0.095 11.3 0.6 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus zf-U1 PF06220.12 RUS87461.1 - 0.13 12.1 17.4 1.1 9.1 2.0 3.7 3 1 0 3 3 3 0 U1 zinc finger zf-C2H2_4 PF13894.6 RUS87461.1 - 0.45 11.5 9.1 19 6.4 0.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Actin_micro PF17003.5 RUS87461.1 - 0.59 9.2 7.6 0.14 11.3 0.3 2.6 2 1 0 2 2 2 0 Putative actin-like family zf-C2H2 PF00096.26 RUS87461.1 - 1.7 9.2 15.3 3.1 8.4 0.2 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.14 RUS87462.1 - 1.8e-10 40.4 0.3 7e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AhpC-TSA PF00578.21 RUS87462.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family SOUL PF04832.12 RUS87464.1 - 6.8e-37 127.2 0.1 7.7e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.12 RUS87465.1 - 2.3e-34 119.0 0.1 2.7e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Hormone_recep PF00104.30 RUS87467.1 - 1.6e-29 102.9 0.1 4.1e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS87467.1 - 1.7e-18 66.8 11.1 3.7e-18 65.7 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) 7tm_1 PF00001.21 RUS87468.1 - 4.6e-11 42.5 3.5 6e-11 42.2 3.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATG27 PF09451.10 RUS87469.1 - 1.3e-10 41.6 0.3 1.8e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 RUS87469.1 - 1.2e-07 31.1 0.1 2e-07 30.4 0.1 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 RUS87469.1 - 0.0011 19.0 1.8 0.0038 17.3 0.2 2.2 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat AC_N PF16214.5 RUS87471.1 - 3.4e-18 66.0 4.8 3.8e-18 65.8 4.8 1.1 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region TssN PF17555.2 RUS87471.1 - 1.7 7.9 10.0 2.3 7.5 10.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Suv3_N PF18114.1 RUS87472.1 - 3.5e-43 146.5 0.2 9.5e-43 145.1 0.2 1.8 1 0 0 1 1 1 1 Suv3 helical N-terminal domain Suv3_C_1 PF18147.1 RUS87472.1 - 4e-18 65.0 2.5 9.5e-18 63.8 2.5 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 RUS87472.1 - 3.7e-16 58.8 0.1 1.5e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 RUS87472.1 - 2.9e-11 43.7 0.2 8.4e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Kinesin_assoc PF16183.5 RUS87472.1 - 0.28 11.3 2.4 0.44 10.7 1.5 1.7 2 0 0 2 2 2 0 Kinesin-associated DUF1043 PF06295.12 RUS87473.1 - 0.71 9.9 5.9 21 5.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) Miff PF05644.11 RUS87474.1 - 1.1e-34 120.4 0.1 2.6e-20 73.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial and peroxisomal fission factor Mff Ribosomal_L19e PF01280.20 RUS87475.1 - 4.5e-66 221.4 14.7 4.5e-66 221.4 14.7 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e Piwi PF02171.17 RUS87477.1 - 1.6e-112 375.7 0.0 2.3e-112 375.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 RUS87477.1 - 1.3e-34 118.3 0.3 3e-34 117.1 0.1 1.8 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 RUS87477.1 - 3.3e-31 108.8 0.0 2.6e-30 105.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 RUS87477.1 - 3.2e-27 95.0 0.3 5.6e-27 94.2 0.3 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 RUS87477.1 - 1.5e-23 82.2 0.1 3.1e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 RUS87477.1 - 1.4e-13 50.9 0.0 3.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Atrophin-1 PF03154.15 RUS87477.1 - 3.8 5.7 8.1 5.6 5.1 8.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family zf-H2C2_2 PF13465.6 RUS87478.1 - 9.3e-20 70.1 58.0 5.2e-08 33.0 1.9 5.9 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS87478.1 - 3.1e-15 55.7 56.6 0.00017 21.9 2.9 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS87478.1 - 4.7e-12 45.7 50.5 0.0018 18.9 1.9 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RUS87478.1 - 0.043 13.7 0.3 0.043 13.7 0.3 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RUS87478.1 - 0.047 14.0 27.3 0.27 11.6 0.5 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SUIM_assoc PF16619.5 RUS87478.1 - 0.12 12.5 36.8 0.14 12.2 3.2 3.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 GAGA PF09237.11 RUS87478.1 - 0.28 11.0 11.6 1.4 8.8 0.1 3.7 1 1 2 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.10 RUS87478.1 - 1.5 9.0 17.1 0.082 13.0 1.0 3.8 2 2 3 5 5 5 0 Zinc ribbon domain PSS PF03034.15 RUS87479.1 - 1.4e-35 123.4 3.8 1.4e-35 123.4 3.8 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase 7tm_1 PF00001.21 RUS87480.1 - 5.1e-25 88.3 8.4 7.4e-25 87.8 8.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS87480.1 - 5.3e-07 29.3 7.8 7.1e-07 28.9 7.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS87480.1 - 7.2e-06 25.6 6.3 9.7e-06 25.1 6.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv STE3 PF02076.15 RUS87480.1 - 0.0017 17.6 2.6 0.0017 17.6 2.6 1.7 2 0 0 2 2 2 1 Pheromone A receptor MFS_1 PF07690.16 RUS87480.1 - 0.028 13.3 0.4 0.043 12.7 0.4 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3169 PF11368.8 RUS87480.1 - 3.2 7.2 7.9 0.094 12.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ERCC3_RAD25_C PF16203.5 RUS87481.1 - 5.4e-122 405.7 0.9 2.2e-121 403.7 0.9 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 RUS87481.1 - 1e-35 122.6 0.0 3.2e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS87481.1 - 2.9e-14 53.4 0.0 6.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS87481.1 - 1.9e-11 44.3 0.1 4.9e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RUS87481.1 - 0.00028 20.7 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RUS87481.1 - 0.00053 18.8 0.0 0.00064 18.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain NUDIX PF00293.28 RUS87484.1 - 1.1e-13 51.4 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Ank_4 PF13637.6 RUS87484.1 - 5.1e-12 46.1 0.2 2.4e-07 31.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS87484.1 - 1.5e-11 44.8 0.0 2.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS87484.1 - 3e-08 33.8 0.2 2.5e-07 30.9 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NUDIX-like PF09296.11 RUS87484.1 - 8.9e-08 32.7 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_3 PF13606.6 RUS87484.1 - 2.8e-07 30.3 0.1 2.2e-06 27.6 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 RUS87484.1 - 6.7e-06 26.3 0.0 4.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat zf-NADH-PPase PF09297.11 RUS87484.1 - 4.6e-05 23.0 2.5 4.6e-05 23.0 2.5 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain rve_3 PF13683.6 RUS87484.1 - 0.042 13.6 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Sfi1 PF08457.10 RUS87486.1 - 0.0012 17.5 147.5 0.0018 16.9 98.4 5.1 1 1 2 3 3 3 2 Sfi1 spindle body protein Glyco_hydro_20 PF00728.22 RUS87487.1 - 3.5e-78 263.5 0.0 5.6e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 RUS87487.1 - 2.7e-13 50.8 0.0 4.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 RUS87487.1 - 0.089 13.6 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 RIIa PF02197.17 RUS87488.1 - 0.00031 20.4 0.5 0.00061 19.4 0.5 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Exo_endo_phos PF03372.23 RUS87489.1 - 7.5e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.23 RUS87490.1 - 9.5e-95 317.3 1.1 9.5e-95 317.3 1.1 4.3 6 1 0 6 6 6 1 Kinesin motor domain Microtub_bd PF16796.5 RUS87490.1 - 3.2e-12 46.6 0.1 3.2e-12 46.6 0.1 5.2 5 0 0 5 5 5 2 Microtubule binding HetR_C PF18460.1 RUS87490.1 - 0.27 11.2 4.7 1.7 8.6 0.1 4.6 2 1 1 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain ANAPC5 PF12862.7 RUS87490.1 - 6.4 6.9 9.8 9.6 6.3 1.5 3.8 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 TSP_1 PF00090.19 RUS87491.1 - 8.2e-10 38.8 11.3 8.2e-10 38.8 11.3 5.6 6 0 0 6 6 6 2 Thrombospondin type 1 domain TIL PF01826.17 RUS87491.1 - 4e-05 23.8 13.8 4e-05 23.8 13.8 9.6 4 3 2 6 6 6 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 RUS87491.1 - 0.0095 16.2 2.3 0.0095 16.2 2.3 8.3 4 3 2 6 6 6 3 von Willebrand factor type C domain Collagen PF01391.18 RUS87491.1 - 0.13 12.0 5.5 0.24 11.2 5.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Med31 PF05669.12 RUS87492.1 - 0.00053 19.9 35.4 0.62 10.1 9.7 3.7 1 1 3 4 4 4 4 SOH1 Ldl_recept_a PF00057.18 RUS87493.1 - 4.1e-23 81.3 62.0 9.3e-10 38.6 7.5 9.0 9 0 0 9 9 9 4 Low-density lipoprotein receptor domain class A VWD PF00094.25 RUS87493.1 - 1.8e-20 73.8 0.1 1.4e-11 44.9 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 RUS87493.1 - 7.5e-11 42.3 12.0 7.5e-11 42.3 12.0 6.0 7 1 1 8 8 8 1 C8 domain TIL PF01826.17 RUS87493.1 - 4.7e-09 36.3 13.5 4.7e-09 36.3 13.5 11.6 7 3 3 10 10 10 2 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 RUS87494.1 - 1.7e-14 54.4 5.5 1.2e-10 41.8 1.8 2.3 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 RUS87494.1 - 1.8e-09 37.9 4.9 1.8e-09 37.9 4.9 3.0 2 1 0 2 2 2 1 C8 domain EGF PF00008.27 RUS87494.1 - 0.005 17.1 5.4 0.005 17.1 5.4 4.9 5 0 0 5 5 5 1 EGF-like domain Ig_3 PF13927.6 RUS87495.1 - 4.7e-21 75.2 0.1 3.1e-09 37.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS87495.1 - 1.3e-19 70.0 0.0 4.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 RUS87495.1 - 1.9e-18 66.6 2.5 8.6e-11 42.0 0.1 3.0 3 1 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 RUS87495.1 - 2.7e-18 65.9 0.1 4.1e-08 33.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS87495.1 - 2.1e-12 47.2 0.1 8.5e-06 26.0 0.1 2.8 2 2 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS87495.1 - 9.1e-06 25.1 0.0 0.001 18.5 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 RUS87495.1 - 0.00058 19.9 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain zf-RRN7 PF11781.8 RUS87495.1 - 0.014 15.0 0.4 8 6.2 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ig_4 PF16680.5 RUS87495.1 - 0.12 12.7 1.7 25 5.2 0.0 3.5 2 2 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain UQ_con PF00179.26 RUS87497.1 - 3.2e-39 133.8 0.0 3.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UDPGP PF01704.18 RUS87498.1 - 5.1e-69 232.9 0.0 6.3e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RUS87498.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Vps26 PF03643.15 RUS87499.1 - 2.8e-127 423.4 7.3 3.4e-127 423.1 7.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 RUS87499.1 - 5.5e-05 23.6 0.6 0.0035 17.8 0.1 2.8 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RUS87499.1 - 0.029 14.4 2.1 0.64 10.1 0.0 3.2 3 1 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.22 RUS87500.1 - 3e-29 100.6 1.3 4e-15 55.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS87500.1 - 1.2e-07 31.3 0.0 0.0012 18.4 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS87500.1 - 6.6e-07 29.1 0.1 0.044 13.6 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 RUS87500.1 - 0.00057 19.7 0.0 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 RUS87500.1 - 0.3 11.3 2.8 7.7 6.7 0.1 3.0 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter zf-SCNM1 PF15803.5 RUS87501.1 - 1.8e-14 53.0 0.6 3.5e-14 52.1 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 SCNM1_acidic PF15805.5 RUS87501.1 - 1.1e-13 50.7 5.4 2.4e-13 49.6 5.4 1.6 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 YABBY PF04690.13 RUS87501.1 - 0.14 12.8 0.1 0.14 12.8 0.1 2.4 2 1 0 2 2 2 0 YABBY protein zf-RING_4 PF14570.6 RUS87502.1 - 4.5e-20 71.2 12.1 9.4e-20 70.2 12.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 RUS87502.1 - 7.5e-06 25.7 8.3 1.5e-05 24.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 RUS87502.1 - 8.2e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 RUS87502.1 - 0.0012 18.9 1.9 0.021 15.0 3.8 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger Torus PF16131.5 RUS87502.1 - 0.0014 19.3 0.1 0.0053 17.4 0.1 2.0 1 0 0 1 1 1 1 Torus domain zf-RING_2 PF13639.6 RUS87502.1 - 0.0033 17.7 11.4 0.0033 17.7 11.4 2.1 2 0 0 2 2 2 1 Ring finger domain Nup35_RRM_2 PF14605.6 RUS87502.1 - 0.037 14.0 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.25 RUS87502.1 - 0.055 13.3 10.2 0.12 12.2 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vasculin PF15337.6 RUS87502.1 - 0.069 14.0 0.1 0.069 14.0 0.1 2.8 4 0 0 4 4 2 0 Vascular protein family Vasculin-like 1 Baculo_IE-1 PF05290.11 RUS87502.1 - 0.25 11.3 4.4 0.6 10.1 4.4 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 RUS87502.1 - 3.8 7.4 18.4 0.06 13.2 10.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAP PF00956.18 RUS87503.1 - 1.1e-99 333.1 11.3 1.9e-99 332.2 11.3 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ribosomal_S13_N PF08069.12 RUS87504.1 - 3.8e-30 103.7 0.2 7.5e-30 102.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 RUS87504.1 - 2e-14 53.6 2.1 3.4e-14 52.8 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 LMBR1 PF04791.16 RUS87506.1 - 0.12 11.3 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Claudin_2 PF13903.6 RUS87506.1 - 1.3 8.7 11.2 2.8 7.6 11.1 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Aldo_ket_red PF00248.21 RUS87507.1 - 1.9e-59 201.3 0.0 2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chibby PF14645.6 RUS87508.1 - 0.028 14.8 3.9 0.057 13.8 2.6 2.1 1 1 1 2 2 2 0 Chibby family DUF812 PF05667.11 RUS87508.1 - 0.033 13.1 18.4 0.041 12.8 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SBDS_C PF09377.10 RUS87508.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 SBDS protein C-terminal domain Vir_act_alpha_C PF10400.9 RUS87508.1 - 0.84 10.4 10.9 0.24 12.1 0.9 3.1 2 1 0 2 2 2 0 Virulence activator alpha C-term C1q PF00386.21 RUS87511.1 - 2.7e-05 24.4 0.0 8.6e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 C1q domain zf-C4 PF00105.18 RUS87512.1 - 4.1e-24 84.8 17.0 7.2e-24 84.0 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CENP-B_dimeris PF09026.10 RUS87512.1 - 0.053 13.9 20.5 0.12 12.7 20.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RUS87512.1 - 0.11 10.7 8.2 0.14 10.3 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Hormone_recep PF00104.30 RUS87512.1 - 0.14 11.7 0.0 1 8.9 0.1 1.9 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor CDC45 PF02724.14 RUS87512.1 - 0.26 9.5 6.1 0.36 9.1 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RUS87512.1 - 0.75 9.1 8.3 1.1 8.5 8.3 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RUS87512.1 - 1.2 8.4 10.0 1.9 7.8 10.0 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS87512.1 - 1.6 6.8 19.6 2.6 6.0 19.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 RUS87512.1 - 4.3 7.2 8.6 6.5 6.6 8.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Utp14 PF04615.13 RUS87512.1 - 4.9 5.6 6.0 6.7 5.1 6.0 1.1 1 0 0 1 1 1 0 Utp14 protein Aldo_ket_red PF00248.21 RUS87513.1 - 1.1e-08 34.7 0.8 1.6e-08 34.1 0.8 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Trypsin PF00089.26 RUS87514.1 - 2.8e-59 200.6 0.1 3.3e-59 200.4 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS87514.1 - 3.6e-08 34.4 0.1 7.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.16 RUS87515.1 - 3e-08 33.0 0.0 0.003 16.5 0.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Presenilin PF01080.17 RUS87515.1 - 0.00085 18.2 0.1 0.0011 17.8 0.1 1.3 1 0 0 1 1 1 1 Presenilin Neur_chan_memb PF02932.16 RUS87515.1 - 0.016 15.3 0.5 0.024 14.7 0.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 RUS87515.1 - 0.033 15.2 3.7 0.033 15.2 3.7 2.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Eisosome1 PF12757.7 RUS87515.1 - 0.038 14.3 7.8 0.06 13.6 7.8 1.2 1 0 0 1 1 1 0 Eisosome protein 1 SLC12 PF03522.15 RUS87515.1 - 0.045 12.8 2.4 0.054 12.5 2.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 RUS87515.1 - 0.053 12.7 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 RUS87515.1 - 0.12 10.3 1.6 0.14 10.0 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 RUS87515.1 - 0.18 10.1 12.3 0.22 9.8 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 RUS87515.1 - 0.26 12.0 12.9 0.52 11.0 12.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HGTP_anticodon2 PF12745.7 RUS87515.1 - 1.2 8.6 8.1 1.7 8.1 8.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Band_3_cyto PF07565.13 RUS87515.1 - 1.8 8.3 6.1 2.4 7.9 6.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.13 RUS87515.1 - 2.4 8.1 24.1 3.1 7.7 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 RUS87515.1 - 6.2 7.0 9.7 9.2 6.5 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF2722 PF10846.8 RUS87515.1 - 8.7 5.2 20.7 12 4.7 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Shisa PF13908.6 RUS87516.1 - 0.00033 21.0 0.0 0.00033 21.0 0.0 4.6 1 1 5 6 6 6 1 Wnt and FGF inhibitory regulator Lipoprotein_18 PF06804.11 RUS87516.1 - 0.031 13.3 5.1 0.05 12.7 5.1 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein TMIE PF16038.5 RUS87516.1 - 0.048 13.5 1.1 0.048 13.5 1.1 1.6 2 0 0 2 2 2 0 TMIE protein Itfg2 PF15907.5 RUS87516.1 - 0.38 9.8 2.2 0.61 9.1 2.2 1.2 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 LapA_dom PF06305.11 RUS87516.1 - 0.63 9.9 2.3 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain WBP-1 PF11669.8 RUS87516.1 - 2.5 8.8 0.0 2.5 8.8 0.0 3.1 2 1 1 3 3 3 0 WW domain-binding protein 1 Sugar_tr PF00083.24 RUS87517.1 - 4.7e-28 98.2 27.5 7.4e-28 97.6 27.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS87517.1 - 1e-08 34.5 39.9 1e-08 34.5 39.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Hormone_recep PF00104.30 RUS87520.1 - 2.2e-21 76.4 6.1 6.2e-13 48.8 0.0 3.3 3 1 1 4 4 4 2 Ligand-binding domain of nuclear hormone receptor Motilin_ghrelin PF04644.12 RUS87520.1 - 6.7 6.6 6.5 18 5.2 0.1 2.8 3 0 0 3 3 3 0 Motilin/ghrelin Ribosomal_S2 PF00318.20 RUS87521.1 - 5.9e-36 123.7 0.0 5.3e-20 71.6 0.0 2.1 1 1 0 2 2 2 2 Ribosomal protein S2 UPF0175 PF03683.13 RUS87522.1 - 0.031 14.0 0.3 7.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) 2TM PF13239.6 RUS87522.1 - 0.12 12.7 1.5 0.53 10.6 1.5 1.8 1 1 1 2 2 2 0 2TM domain DHHC PF01529.20 RUS87522.1 - 0.25 11.4 1.9 0.62 10.2 2.0 1.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase Babuvirus_MP PF07234.11 RUS87522.1 - 0.35 11.0 3.4 2.2 8.5 0.1 2.3 1 1 1 2 2 2 0 Movement and RNA silencing protein DUF4713 PF15831.5 RUS87522.1 - 0.69 10.4 8.2 5.7 7.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Lectin_C PF00059.21 RUS87524.1 - 7.6e-09 36.3 0.0 3.2e-08 34.3 0.0 2.1 1 0 0 1 1 1 1 Lectin C-type domain AMIN PF11741.8 RUS87524.1 - 0.015 15.4 26.0 0.57 10.3 1.3 6.5 1 1 5 6 6 6 0 AMIN domain MAM33 PF02330.16 RUS87524.1 - 2.1 8.2 48.3 0.5 10.3 11.8 3.7 1 1 2 3 3 3 0 Mitochondrial glycoprotein SR-25 PF10500.9 RUS87526.1 - 0.052 13.2 7.1 0.061 12.9 7.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 RUS87527.1 - 0.015 15.4 0.3 0.02 14.9 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 RUS87527.1 - 0.044 12.6 18.0 0.16 10.8 8.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 RUS87527.1 - 1.7 7.8 2.4 1.6 7.8 0.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Vps39_2 PF10367.9 RUS87528.1 - 7e-27 94.0 1.0 1.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 RUS87528.1 - 8.4e-19 67.9 1.3 9e-15 54.9 0.0 3.7 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 RUS87528.1 - 4.4e-16 59.3 0.2 8.3e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 RUS87528.1 - 1e-15 57.9 2.0 3e-09 36.9 1.4 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS eIF-5a PF01287.20 RUS87528.1 - 0.16 12.1 0.2 22 5.2 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold ARS2 PF04959.13 RUS87528.1 - 0.25 11.7 0.5 0.53 10.6 0.0 1.7 2 0 0 2 2 2 0 Arsenite-resistance protein 2 TPR_2 PF07719.17 RUS87528.1 - 0.29 11.4 5.1 5.9 7.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RUS87528.1 - 1.4 9.3 4.3 68 3.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS87528.1 - 3.6 7.6 7.2 37 4.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rpp20 PF12328.8 RUS87529.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Dimerisation PF08100.11 RUS87529.1 - 0.16 12.0 0.1 1.4 9.0 0.0 2.3 1 1 1 2 2 2 0 Dimerisation domain PsbM PF05151.12 RUS87529.1 - 0.21 11.4 4.4 42 4.0 0.0 3.6 3 1 1 4 4 4 0 Photosystem II reaction centre M protein (PsbM) Endonuclease_NS PF01223.23 RUS87530.1 - 0.037 13.8 0.0 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Serglycin PF04360.12 RUS87530.1 - 6.2 6.8 6.8 6.3 6.7 0.6 2.4 2 0 0 2 2 2 0 Serglycin CARD_2 PF16739.5 RUS87531.1 - 1e-07 31.8 0.2 4.2e-06 26.6 0.0 3.3 2 0 0 2 2 2 1 Caspase recruitment domain La PF05383.17 RUS87531.1 - 0.038 14.0 0.6 0.73 9.9 0.3 3.1 2 0 0 2 2 2 0 La domain DnaJ PF00226.31 RUS87532.1 - 3.2e-23 81.6 2.0 8.9e-23 80.2 2.0 1.8 1 0 0 1 1 1 1 DnaJ domain SEP PF08059.13 RUS87533.1 - 1e-27 96.5 1.1 1.8e-27 95.7 0.1 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 RUS87533.1 - 1.4e-16 60.4 0.2 2.4e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 RUS87533.1 - 3.7e-15 55.5 0.1 6.9e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 RUS87533.1 - 0.0057 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain HCNGP PF07818.13 RUS87534.1 - 2e-32 111.7 0.6 5.7e-32 110.2 0.6 1.8 1 0 0 1 1 1 1 HCNGP-like protein VWA PF00092.28 RUS87535.1 - 2.4e-63 213.5 5.0 4e-28 98.8 0.1 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS87535.1 - 8.7e-35 119.6 1.7 3.6e-13 50.1 0.1 3.6 3 0 0 3 3 3 3 von Willebrand factor type A domain DUF1194 PF06707.11 RUS87535.1 - 6e-05 22.4 3.9 0.042 13.1 1.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_3 PF13768.6 RUS87535.1 - 0.00011 22.2 0.4 0.42 10.5 0.0 3.9 3 1 0 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS87535.1 - 0.0048 16.3 0.6 3 7.2 0.0 3.5 3 1 0 3 3 3 1 VWA domain containing CoxE-like protein CBM_14 PF01607.24 RUS87536.1 - 1e-08 35.2 2.0 1e-08 35.2 2.0 3.7 3 1 0 3 3 3 2 Chitin binding Peritrophin-A domain LicD PF04991.13 RUS87537.1 - 2.6e-14 53.9 2.1 7.6e-07 29.5 1.7 2.1 1 1 1 2 2 2 2 LicD family Sigma54_AID PF00309.20 RUS87538.1 - 0.67 9.9 10.6 3.3 7.7 0.7 3.6 3 2 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Band_7 PF01145.25 RUS87539.1 - 1.9e-14 54.1 0.0 2.2e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family ABC_tran PF00005.27 RUS87540.1 - 4.7e-43 147.0 0.0 2.5e-22 79.9 0.0 4.2 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 RUS87540.1 - 2.4e-15 57.1 7.3 9.2e-05 22.4 0.0 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS87540.1 - 2.4e-13 50.0 7.4 7.1e-05 22.3 0.0 4.2 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RUS87540.1 - 5e-11 42.9 17.1 0.00012 21.9 0.0 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_24 PF13479.6 RUS87540.1 - 2.2e-06 27.5 2.3 0.06 13.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RUS87540.1 - 3.4e-06 27.4 0.2 0.034 14.4 0.1 3.1 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RUS87540.1 - 5.9e-06 26.6 0.4 0.16 12.3 0.0 3.4 3 0 0 3 3 3 2 RNA helicase ABC_tran_Xtn PF12848.7 RUS87540.1 - 1.1e-05 25.3 20.4 1.1e-05 25.3 20.4 4.9 3 2 2 5 5 2 1 ABC transporter AAA PF00004.29 RUS87540.1 - 1.2e-05 25.7 1.9 0.019 15.4 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RUS87540.1 - 2.9e-05 24.4 1.1 0.15 12.3 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 RUS87540.1 - 3e-05 24.1 0.0 0.2 11.7 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RUS87540.1 - 3.3e-05 23.5 4.1 0.015 15.0 0.1 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 RUS87540.1 - 5.5e-05 22.8 0.5 0.062 12.8 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region NACHT PF05729.12 RUS87540.1 - 5.7e-05 23.1 0.2 0.31 10.9 0.1 2.6 2 1 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 RUS87540.1 - 6.6e-05 22.7 0.0 0.19 11.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RUS87540.1 - 7.5e-05 22.7 5.9 0.012 15.5 0.0 3.4 3 1 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 RUS87540.1 - 0.00017 22.0 2.3 0.36 11.2 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 RUS87540.1 - 0.0003 20.8 5.0 0.0079 16.3 0.0 3.8 4 1 0 4 4 3 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 RUS87540.1 - 0.00057 19.8 0.1 1.5 8.7 0.1 2.9 2 1 0 2 2 2 2 NTPase IstB_IS21 PF01695.17 RUS87540.1 - 0.0015 18.3 0.3 0.58 9.9 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 RUS87540.1 - 0.0034 17.9 0.0 0.048 14.2 0.0 5.6 5 1 0 5 5 3 2 AAA domain cobW PF02492.19 RUS87540.1 - 0.0037 16.9 4.3 0.055 13.1 0.0 3.4 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 RUS87540.1 - 0.0038 16.8 0.2 2.4 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 RUS87540.1 - 0.0049 16.5 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 RUS87540.1 - 0.0049 16.9 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 RUS87540.1 - 0.0058 16.8 1.2 5.2 7.3 0.0 3.3 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 RUS87540.1 - 0.026 14.7 0.2 3.8 7.8 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 RUS87540.1 - 0.035 14.3 9.3 0.64 10.2 0.0 3.8 4 1 1 5 5 2 0 AAA domain TsaE PF02367.17 RUS87540.1 - 0.055 13.5 0.0 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 RUS87540.1 - 0.1 12.1 0.1 4.5 6.8 0.0 3.2 4 0 0 4 4 4 0 Ferrous iron transport protein B PHM7_ext PF12621.8 RUS87540.1 - 1.2 9.4 6.6 4 7.7 6.3 2.2 1 1 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter DUF87 PF01935.17 RUS87540.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.6 3 1 1 4 4 3 0 Helicase HerA, central domain Dynamin_N PF00350.23 RUS87540.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.9 4 2 0 4 4 3 0 Dynamin family Band_7 PF01145.25 RUS87541.1 - 6.4e-19 68.6 0.0 6.4e-19 68.6 0.0 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 RUS87541.1 - 2.6e-08 34.1 16.1 2.6e-08 34.1 16.1 3.5 2 1 1 3 3 3 1 Flotillin Herpes_gE PF02480.16 RUS87541.1 - 0.068 11.9 0.1 0.098 11.4 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AKNA PF12443.8 RUS87544.1 - 0.0043 17.7 0.5 0.11 13.1 0.0 2.7 2 1 0 2 2 2 1 AT-hook-containing transcription factor DUF4303 PF14136.6 RUS87544.1 - 0.0062 16.3 0.3 0.013 15.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) DUF745 PF05335.13 RUS87544.1 - 0.35 10.6 2.3 1.2 8.8 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF745) RNase_H PF00075.24 RUS87546.1 - 3.8e-08 33.6 0.0 6.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF1482 PF07358.11 RUS87546.1 - 0.11 12.4 0.6 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) VWA PF00092.28 RUS87547.1 - 2.4e-40 138.6 1.2 3.7e-40 138.0 1.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS87547.1 - 4.2e-17 62.7 0.1 1.3e-16 61.1 0.1 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain CBM_14 PF01607.24 RUS87547.1 - 9.9e-06 25.6 1.8 2.4e-05 24.4 1.8 1.7 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain VWA_3 PF13768.6 RUS87547.1 - 1.1e-05 25.4 0.0 5.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain 7tm_1 PF00001.21 RUS87548.1 - 1.1e-23 84.0 16.5 1.7e-23 83.3 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87548.1 - 0.0036 17.0 18.5 0.026 14.2 18.3 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS87549.1 - 9e-15 54.7 7.1 1e-14 54.5 7.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS87549.1 - 0.00018 21.0 5.6 0.00021 20.7 5.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM171 PF15471.6 RUS87549.1 - 0.092 11.7 0.1 0.092 11.7 0.1 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 7TM_GPCR_Srw PF10324.9 RUS87549.1 - 0.25 10.6 4.8 0.11 11.8 1.1 1.9 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw YrvL PF14184.6 RUS87549.1 - 0.62 10.2 11.0 0.49 10.5 1.2 2.4 2 1 0 2 2 2 0 Regulatory protein YrvL Arteri_Gl PF00951.18 RUS87549.1 - 6.8 6.5 12.4 0.53 10.1 1.6 2.2 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein Abhydro_lipase PF04083.16 RUS87550.1 - 0.00011 21.6 6.7 41 3.8 0.0 6.0 6 0 0 6 6 6 0 Partial alpha/beta-hydrolase lipase region DUF3223 PF11523.8 RUS87550.1 - 0.00019 22.2 5.8 14 6.6 0.2 4.8 1 1 3 4 4 4 2 Protein of unknown function (DUF3223) Curto_V2 PF07325.11 RUS87550.1 - 0.01 15.7 0.1 5.3 6.9 0.0 2.4 1 1 2 3 3 3 0 Curtovirus V2 protein DUF2807 PF10988.8 RUS87550.1 - 0.06 13.1 10.7 0.99 9.2 1.5 2.5 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain PAW PF04721.17 RUS87550.1 - 0.2 11.4 10.4 0.69 9.7 4.0 2.3 1 1 1 2 2 2 0 PNGase C-terminal domain, mannose-binding module PAW BORCS7 PF16088.5 RUS87550.1 - 1.7 9.0 24.5 4.8 7.5 4.5 3.3 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 ICAM_N PF03921.14 RUS87550.1 - 3.7 7.3 11.4 6.5 6.5 0.4 3.2 1 1 3 4 4 4 0 Intercellular adhesion molecule (ICAM), N-terminal domain LRR_1 PF00560.33 RUS87550.1 - 6.3 7.8 12.2 1.7e+02 3.4 0.7 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat Muted PF14942.6 RUS87550.1 - 7.6 6.9 8.8 15 5.9 1.8 2.3 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4371 PF14291.6 RUS87552.1 - 8.6e-08 32.1 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Methyltr_RsmB-F PF01189.17 RUS87554.1 - 2.4e-29 102.4 0.0 1.5e-16 60.6 0.0 2.6 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 RUS87554.1 - 0.00054 19.9 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.19 RUS87554.1 - 0.00061 19.9 0.0 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 RUS87554.1 - 0.0035 16.5 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Armet PF10208.9 RUS87555.1 - 5.3e-53 178.8 6.5 7e-53 178.5 6.5 1.1 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding OS-D PF03392.13 RUS87555.1 - 0.02 15.0 0.6 0.02 15.0 0.6 2.4 3 0 0 3 3 3 0 Insect pheromone-binding family, A10/OS-D Mab-21 PF03281.14 RUS87556.1 - 1.3e-10 41.1 0.0 5.3e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Mab-21 protein PadR PF03551.14 RUS87556.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RAD51_interact PF15696.5 RUS87556.1 - 0.93 9.6 4.4 0.53 10.4 0.2 2.4 2 0 0 2 2 2 0 RAD51 interacting motif Pkinase_Tyr PF07714.17 RUS87557.1 - 9e-84 280.8 0.0 1.3e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS87557.1 - 1.8e-36 125.9 0.0 2.8e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 RUS87557.1 - 0.025 14.7 1.8 0.86 9.7 0.2 3.4 3 1 0 3 3 3 0 IPT/TIG domain Kinase-like PF14531.6 RUS87557.1 - 0.04 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DapB_C PF05173.14 RUS87557.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus TIG PF01833.24 RUS87558.1 - 1.9e-17 63.1 9.7 1.9e-06 27.8 0.8 3.8 3 0 0 3 3 3 3 IPT/TIG domain TubC_N PF18563.1 RUS87558.1 - 0.0077 16.2 0.0 11 6.1 0.0 3.2 4 0 0 4 4 4 2 TubC N-terminal docking domain fn3_2 PF16893.5 RUS87558.1 - 0.013 15.6 0.1 4.9 7.4 0.0 2.6 1 1 1 2 2 2 0 Fibronectin type III domain PSI PF01437.25 RUS87558.1 - 0.022 15.3 14.1 0.022 15.3 14.1 2.3 2 0 0 2 2 2 0 Plexin repeat PDZ_6 PF17820.1 RUS87558.1 - 0.13 12.2 0.0 39 4.2 0.0 3.2 4 0 0 4 4 4 0 PDZ domain PSI_integrin PF17205.3 RUS87558.1 - 1.1 9.0 21.1 0.1 12.4 14.3 2.4 2 0 0 2 2 2 0 Integrin plexin domain MGC-24 PF05283.11 RUS87558.1 - 2 8.9 11.4 0.13 12.7 5.4 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sema PF01403.19 RUS87559.1 - 4.3e-14 52.2 0.1 3.5e-09 36.0 0.0 2.0 2 0 0 2 2 2 2 Sema domain IPTL-CTERM PF18203.1 RUS87561.1 - 0.14 12.1 4.4 0.27 11.2 4.4 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif PB1 PF00564.24 RUS87562.1 - 9.2e-10 38.3 0.1 1.5e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 PB1 domain GTP_EFTU_D2 PF03144.25 RUS87562.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 TFIIA PF03153.13 RUS87562.1 - 0.14 12.1 35.2 0.21 11.5 35.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 RUS87562.1 - 1.1 9.2 3.5 1.6 8.7 3.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 RUS87562.1 - 1.5 7.9 13.1 1.9 7.6 13.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Lin-8 PF03353.15 RUS87562.1 - 5.6 6.4 12.2 8.8 5.8 12.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Acyl-CoA_dh_1 PF00441.24 RUS87563.1 - 1.9e-47 161.2 0.6 2.9e-47 160.6 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS87563.1 - 1.2e-26 92.8 0.0 2.3e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS87563.1 - 2.8e-25 89.2 0.1 5.7e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS87563.1 - 1.6e-22 80.2 0.1 2.3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DGCR6 PF07324.11 RUS87564.1 - 7.9e-73 244.2 10.4 9.4e-73 244.0 10.4 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 RUS87564.1 - 5.7e-06 26.1 4.3 9.9e-06 25.3 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) FhuF PF06276.12 RUS87564.1 - 0.01 16.3 1.5 0.016 15.6 1.5 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Radial_spoke PF04712.12 RUS87564.1 - 0.04 12.9 0.9 0.05 12.5 0.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein STAR_dimer PF16544.5 RUS87565.1 - 2.7e-23 81.3 0.4 4.9e-23 80.4 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 RUS87565.1 - 6.5e-06 25.9 0.1 1.5e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 KH domain MRP-S32 PF10210.9 RUS87567.1 - 0.1 13.2 2.8 0.39 11.3 2.8 2.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 HAUS-augmin3 PF14932.6 RUS87567.1 - 3.1 7.3 12.0 0.083 12.5 5.4 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 fn3 PF00041.21 RUS87568.1 - 1.3e-39 134.4 24.1 2.3e-08 34.3 0.0 9.9 8 2 0 8 8 8 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS87568.1 - 5.1e-06 27.0 0.3 0.0017 18.9 0.2 6.5 7 1 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RUS87568.1 - 1.2e-05 25.5 0.0 1.3 9.5 0.0 5.1 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) Glyco_hydro_36N PF16875.5 RUS87568.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain Y_phosphatase PF00102.27 RUS87569.1 - 9.2e-56 189.0 0.6 3.4e-28 98.8 0.1 3.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 RUS87569.1 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS87569.1 - 0.00059 20.0 0.0 0.0017 18.5 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RUS87569.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family C2 PF00168.30 RUS87570.1 - 1.3e-39 134.6 0.0 8.7e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 RUS87570.1 - 3.7e-05 23.7 0.2 0.011 15.6 0.0 2.7 4 0 0 4 4 4 2 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.6 RUS87570.1 - 0.003 17.4 0.1 0.038 13.8 0.1 2.1 1 1 1 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Lectin_C PF00059.21 RUS87571.1 - 3e-14 53.7 1.5 3.7e-14 53.4 1.5 1.0 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS87572.1 - 2e-09 38.1 0.1 2.4e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 RUS87572.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like MIG-14_Wnt-bd PF06664.12 RUS87573.1 - 5e-95 318.1 32.1 5e-95 318.1 32.1 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Cadherin_3 PF16184.5 RUS87574.1 - 0.16 12.0 2.9 21 5.1 0.1 3.6 2 2 3 5 5 5 0 Cadherin-like dUTPase PF00692.19 RUS87575.1 - 7.2e-06 25.7 5.4 0.89 9.3 0.1 3.4 1 1 0 3 3 3 3 dUTPase DAGK_acc PF00609.19 RUS87576.1 - 6.1e-32 111.2 0.0 1.1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RUS87576.1 - 8.5e-27 93.3 0.0 2.1e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_5 PF13857.6 RUS87576.1 - 5.4e-15 55.3 0.3 2.2e-06 27.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS87576.1 - 4.2e-12 46.5 0.1 8.3e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS87576.1 - 2.4e-08 33.6 0.0 0.00046 20.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RUS87576.1 - 2.5e-08 34.3 0.6 1.9e-05 25.1 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS87576.1 - 3.2e-08 33.7 0.4 0.0022 18.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat C1_1 PF00130.22 RUS87576.1 - 1.5e-07 31.1 8.1 0.00015 21.5 1.7 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 RUS87576.1 - 7.4 6.5 8.6 17 5.4 0.5 2.8 2 0 0 2 2 2 0 PHD-finger Tctex-1 PF03645.13 RUS87577.1 - 7.8e-17 61.4 0.1 1.2e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family RRN3 PF05327.11 RUS87577.1 - 0.053 12.1 18.8 0.068 11.7 18.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 RUS87577.1 - 0.11 12.1 16.5 0.14 11.7 16.5 1.4 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 RUS87577.1 - 0.13 12.1 7.9 0.19 11.6 7.9 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 RUS87577.1 - 0.89 7.8 23.0 1.1 7.5 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 RUS87577.1 - 2 6.8 11.7 2.3 6.6 11.7 1.3 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 RUS87577.1 - 5.5 5.0 48.8 8.3 4.4 48.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 RUS87577.1 - 8.3 5.7 20.4 13 5.1 20.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 RUS87577.1 - 8.6 5.7 27.4 11 5.3 27.4 1.2 1 0 0 1 1 1 0 SDA1 TRAP-gamma PF07074.12 RUS87578.1 - 0.11 12.0 3.7 0.12 11.9 1.2 2.2 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) TRIQK PF15168.6 RUS87578.1 - 0.78 9.7 0.0 0.78 9.7 0.0 3.0 4 0 0 4 4 4 0 Triple QxxK/R motif-containing protein family RRM_1 PF00076.22 RUS87579.1 - 8e-50 166.6 0.0 2.4e-15 56.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 RUS87579.1 - 2.6e-07 30.6 0.0 0.26 11.3 0.0 3.8 3 1 0 3 3 3 3 RNA binding domain PHM7_cyt PF14703.6 RUS87579.1 - 2.4e-05 24.6 0.2 1.3 9.2 0.0 3.5 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 RUS87579.1 - 0.00014 21.9 0.2 0.2 11.8 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS87579.1 - 0.074 13.1 0.0 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cpn60_TCP1 PF00118.24 RUS87580.1 - 3.9e-147 490.8 12.8 4.4e-147 490.6 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.9 RUS87580.1 - 0.081 12.6 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Xan_ur_permease PF00860.20 RUS87581.1 - 5.3e-66 222.9 17.6 7e-66 222.5 17.6 1.1 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 RUS87581.1 - 0.24 11.8 23.1 0.42 11.0 2.1 3.8 2 1 2 4 4 4 0 Molybdate transporter of MFS superfamily SpoIIIAC PF06686.11 RUS87581.1 - 0.48 10.7 0.1 0.48 10.7 0.1 4.8 6 0 0 6 6 6 0 Stage III sporulation protein AC/AD protein family ApeC PF16977.5 RUS87582.1 - 2.5e-49 168.0 2.0 3.9e-49 167.4 2.0 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin MACPF PF01823.19 RUS87582.1 - 8.3e-10 39.1 1.5 5.5e-09 36.4 1.0 2.1 1 1 1 2 2 2 1 MAC/Perforin domain PKD_channel PF08016.12 RUS87583.1 - 1.3e-06 27.4 14.4 1.7e-06 27.0 14.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel SieB PF14163.6 RUS87583.1 - 0.062 12.8 1.3 0.11 12.0 1.3 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B PKD_channel PF08016.12 RUS87584.1 - 1.2e-20 73.6 0.4 1.7e-20 73.1 0.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel HCO3_cotransp PF00955.21 RUS87584.1 - 0.029 13.2 0.4 0.047 12.5 0.0 1.5 2 0 0 2 2 2 0 HCO3- transporter family TUDOR PF00567.24 RUS87586.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tudor domain BH3 PF15285.6 RUS87587.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting 7tm_1 PF00001.21 RUS87589.1 - 4.1e-07 29.6 21.8 1.6e-06 27.7 8.5 2.5 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 2-oxoacid_dh PF00198.23 RUS87589.1 - 0.04 13.4 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) WD40 PF00400.32 RUS87590.1 - 8e-36 121.5 26.6 3.9e-07 30.6 0.1 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat PQQ_3 PF13570.6 RUS87590.1 - 6.1e-08 32.9 12.5 0.038 14.5 0.1 6.8 6 2 1 7 7 7 3 PQQ-like domain Nup160 PF11715.8 RUS87590.1 - 3e-07 29.5 5.7 0.036 12.7 0.0 5.5 3 3 4 7 7 7 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RUS87590.1 - 4.2e-06 27.0 0.1 0.25 11.6 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RUS87590.1 - 0.0078 15.0 0.1 1.1 8.0 0.0 3.2 2 1 1 3 3 3 1 Nup133 N terminal like PH_4 PF15404.6 RUS87590.1 - 0.86 9.4 2.9 3.7 7.3 0.7 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain EzrA PF06160.12 RUS87591.1 - 2.4e-10 39.3 15.8 1.8e-06 26.5 0.1 3.4 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Spc7 PF08317.11 RUS87591.1 - 3.4e-10 39.3 19.9 1e-05 24.6 1.3 4.3 1 1 4 5 5 5 3 Spc7 kinetochore protein DUF1664 PF07889.12 RUS87591.1 - 4.1e-10 39.8 32.1 0.0071 16.4 0.1 7.3 2 2 4 7 7 7 4 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RUS87591.1 - 3.4e-09 36.9 16.0 0.025 14.6 0.0 6.4 1 1 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.11 RUS87591.1 - 5.5e-07 28.7 15.8 3.6e-06 26.0 6.5 2.5 1 1 1 2 2 2 2 Weak chloroplast movement under blue light AAA_13 PF13166.6 RUS87591.1 - 7.2e-07 28.3 27.0 0.01 14.5 3.8 3.2 1 1 1 3 3 3 3 AAA domain Fez1 PF06818.15 RUS87591.1 - 8.1e-07 29.7 16.9 0.017 15.6 2.6 4.5 1 1 2 4 4 4 2 Fez1 ATG16 PF08614.11 RUS87591.1 - 3.6e-06 27.3 18.8 0.01 16.0 3.6 4.8 1 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Filament PF00038.21 RUS87591.1 - 5.5e-06 26.2 18.4 0.11 12.1 4.8 5.0 1 1 3 5 5 5 2 Intermediate filament protein Laminin_II PF06009.12 RUS87591.1 - 7.3e-06 26.0 42.8 9.4e-05 22.5 2.2 6.3 1 1 4 5 5 5 2 Laminin Domain II APG6_N PF17675.1 RUS87591.1 - 1.4e-05 25.6 1.8 0.091 13.3 0.0 3.8 3 1 1 4 4 3 1 Apg6 coiled-coil region MAD PF05557.13 RUS87591.1 - 1.8e-05 23.4 10.2 0.0018 16.7 0.8 3.1 1 1 0 2 2 2 2 Mitotic checkpoint protein HAP1_N PF04849.13 RUS87591.1 - 2.4e-05 23.7 13.3 0.015 14.5 0.2 3.9 1 1 3 4 4 4 1 HAP1 N-terminal conserved region ADIP PF11559.8 RUS87591.1 - 6.3e-05 23.1 17.9 0.34 11.0 3.2 5.8 4 2 2 6 6 6 2 Afadin- and alpha -actinin-Binding DUF713 PF05218.14 RUS87591.1 - 8.2e-05 22.4 8.6 0.11 12.2 0.2 4.3 3 1 0 3 3 3 1 Protein of unknown function (DUF713) DUF5082 PF16888.5 RUS87591.1 - 0.00011 22.5 26.7 0.025 14.9 2.3 5.9 2 1 2 5 5 5 1 Domain of unknown function (DUF5082) Tup_N PF08581.10 RUS87591.1 - 0.00016 21.9 9.3 3.6 8.0 0.1 6.5 4 3 4 8 8 8 0 Tup N-terminal HMMR_N PF15905.5 RUS87591.1 - 0.00025 20.6 24.0 0.16 11.4 3.3 4.0 2 2 1 4 4 4 3 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 RUS87591.1 - 0.00027 20.9 6.1 8.4 6.5 0.0 6.2 3 1 1 5 5 5 0 TolA binding protein trimerisation Mod_r PF07200.13 RUS87591.1 - 0.00037 20.6 13.7 0.098 12.8 0.1 4.7 2 2 1 4 4 4 1 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 RUS87591.1 - 0.00042 20.7 35.4 2 8.9 2.4 9.1 2 2 5 7 7 7 1 Nucleopolyhedrovirus P10 protein Nup54 PF13874.6 RUS87591.1 - 0.00052 20.1 9.9 0.2 11.7 0.0 4.9 2 1 3 5 5 5 1 Nucleoporin complex subunit 54 GAS PF13851.6 RUS87591.1 - 0.00066 19.1 14.1 0.19 11.1 0.1 4.7 1 1 5 6 6 6 2 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 RUS87591.1 - 0.00069 19.5 14.3 0.25 11.1 0.3 4.5 1 1 3 4 4 4 3 Protein of unknown function (DUF724) LPP PF04728.13 RUS87591.1 - 0.001 19.4 32.6 6.8 7.2 0.2 9.8 7 3 4 11 11 8 0 Lipoprotein leucine-zipper CALCOCO1 PF07888.11 RUS87591.1 - 0.0013 17.7 14.6 0.029 13.2 0.1 3.4 2 2 1 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2730 PF10805.8 RUS87591.1 - 0.0013 18.8 17.9 4.2 7.5 0.3 7.4 2 1 5 8 8 8 0 Protein of unknown function (DUF2730) Atg14 PF10186.9 RUS87591.1 - 0.0013 17.8 15.9 0.0075 15.4 3.0 3.7 1 1 1 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 RUS87591.1 - 0.0026 16.8 24.0 0.2 10.6 1.2 3.9 1 1 0 3 3 3 2 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 RUS87591.1 - 0.0028 17.5 20.8 0.031 14.1 1.0 3.7 2 2 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 RUS87591.1 - 0.0028 17.7 14.6 0.19 11.8 0.1 5.8 3 3 2 5 5 5 2 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 RUS87591.1 - 0.0034 16.8 7.0 0.69 9.2 0.0 4.6 3 1 1 5 5 4 1 Tropomyosin COG5 PF10392.9 RUS87591.1 - 0.0049 17.0 23.7 0.15 12.2 0.3 6.3 2 2 4 7 7 7 1 Golgi transport complex subunit 5 Cast PF10174.9 RUS87591.1 - 0.0055 15.0 21.6 0.0087 14.4 15.5 2.4 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone PI3K_P85_iSH2 PF16454.5 RUS87591.1 - 0.006 16.2 6.8 0.84 9.2 0.3 5.2 2 2 2 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain UPF0242 PF06785.11 RUS87591.1 - 0.0063 16.6 6.1 1.9 8.5 0.7 3.7 2 1 2 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 RUS87591.1 - 0.0066 16.3 31.2 0.69 9.7 0.8 5.9 2 2 2 5 5 5 1 Bacillus haemolytic enterotoxin (HBL) DUF3450 PF11932.8 RUS87591.1 - 0.0082 15.5 20.1 0.26 10.5 0.3 5.1 2 2 2 5 5 5 1 Protein of unknown function (DUF3450) DUF4795 PF16043.5 RUS87591.1 - 0.0088 15.7 1.9 0.0088 15.7 1.9 4.5 1 1 1 3 3 3 1 Domain of unknown function (DUF4795) SlyX PF04102.12 RUS87591.1 - 0.0094 16.6 5.9 36 5.1 0.0 6.4 4 3 2 6 6 6 0 SlyX ZapB PF06005.12 RUS87591.1 - 0.0097 16.3 10.8 2.7 8.5 0.0 5.3 3 2 0 4 4 3 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 RUS87591.1 - 0.01 16.1 16.4 0.063 13.5 0.5 5.3 2 2 3 6 6 6 1 Seryl-tRNA synthetase N-terminal domain DUF4763 PF15960.5 RUS87591.1 - 0.01 15.2 1.9 1 8.6 0.0 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4763) PI_PP_I PF18363.1 RUS87591.1 - 0.017 15.3 6.3 4.4 7.6 0.0 4.9 2 2 2 5 5 4 0 Phosphoinositide phosphatase insertion domain Fib_alpha PF08702.10 RUS87591.1 - 0.024 14.8 33.3 0.03 14.5 2.4 5.5 1 1 2 5 5 5 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 RUS87591.1 - 0.028 14.6 20.6 2.4 8.4 0.8 5.8 3 3 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF211 PF02680.14 RUS87591.1 - 0.029 14.5 6.0 0.2 11.8 1.5 3.7 2 1 1 3 3 2 0 Uncharacterized ArCR, COG1888 DUF948 PF06103.11 RUS87591.1 - 0.042 14.1 38.3 3 8.2 2.7 7.1 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 RUS87591.1 - 0.05 13.3 26.8 0.091 12.4 4.9 4.8 1 1 5 6 6 6 0 Laminin Domain I Lebercilin PF15619.6 RUS87591.1 - 0.054 13.2 12.7 0.11 12.2 0.6 4.6 4 2 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 RUS87591.1 - 0.058 13.5 9.2 6.5 6.9 0.3 4.5 3 1 1 4 4 4 0 Tropomyosin like HALZ PF02183.18 RUS87591.1 - 0.058 13.6 4.1 20 5.5 0.0 5.1 5 1 2 7 7 5 0 Homeobox associated leucine zipper HsbA PF12296.8 RUS87591.1 - 0.084 13.3 27.7 4.7 7.7 4.2 7.1 1 1 5 6 6 6 0 Hydrophobic surface binding protein A SYCE1 PF15233.6 RUS87591.1 - 0.087 12.9 3.9 8.4 6.4 0.1 3.8 3 1 1 4 4 4 0 Synaptonemal complex central element protein 1 Fungal_TACC PF12709.7 RUS87591.1 - 0.088 13.3 8.7 4.8 7.7 0.1 5.4 3 2 2 5 5 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins KELK PF15796.5 RUS87591.1 - 0.11 13.0 5.0 2 8.9 0.2 3.8 3 1 0 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FlaC_arch PF05377.11 RUS87591.1 - 0.11 12.9 34.0 6 7.3 0.0 9.6 5 4 4 9 9 9 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 RUS87591.1 - 0.13 12.5 6.2 6.5 7.0 0.1 4.4 3 3 2 5 5 5 0 Flagellar FliJ protein DUF2968 PF11180.8 RUS87591.1 - 0.15 11.7 5.1 1.8 8.2 0.0 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF2968) Myosin_tail_1 PF01576.19 RUS87591.1 - 0.18 9.6 15.9 1 7.1 7.5 2.8 1 1 1 2 2 2 0 Myosin tail TMPIT PF07851.13 RUS87591.1 - 0.22 10.7 18.3 0.84 8.8 1.1 4.3 1 1 4 5 5 5 0 TMPIT-like protein DUF2576 PF10845.8 RUS87591.1 - 0.23 11.1 0.9 6.1 6.5 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Sec34 PF04136.15 RUS87591.1 - 0.29 11.0 21.7 0.77 9.6 1.0 6.0 2 1 2 6 6 6 0 Sec34-like family ERM PF00769.19 RUS87591.1 - 0.3 10.9 7.8 8.2 6.2 0.0 3.4 2 2 1 3 3 3 0 Ezrin/radixin/moesin family PTRF_SDPR PF15237.6 RUS87591.1 - 0.33 10.5 21.5 0.37 10.4 1.7 4.2 2 1 0 4 4 4 0 PTRF/SDPR family COG2 PF06148.11 RUS87591.1 - 0.46 10.6 28.1 11 6.2 0.2 7.3 2 2 3 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 RUS87591.1 - 0.46 10.7 14.3 7.6 6.7 0.5 4.5 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF2205 PF10224.9 RUS87591.1 - 0.48 10.5 3.6 9.6 6.3 0.0 3.8 3 3 1 4 4 2 0 Short coiled-coil protein Ski2_N PF17911.1 RUS87591.1 - 0.57 10.0 2.9 0.9 9.3 1.0 2.4 2 0 0 2 2 1 0 Ski2 N-terminal region DivIC PF04977.15 RUS87591.1 - 0.63 9.9 15.2 17 5.3 0.4 6.8 6 2 4 10 10 7 0 Septum formation initiator SMC_Nse1 PF07574.13 RUS87591.1 - 0.66 9.8 10.1 8.1 6.3 0.4 4.2 2 1 2 5 5 5 0 Nse1 non-SMC component of SMC5-6 complex YabA PF06156.13 RUS87591.1 - 0.66 10.6 21.2 1.5 9.5 0.4 6.3 3 3 3 6 6 5 0 Initiation control protein YabA CENP-Q PF13094.6 RUS87591.1 - 0.73 10.0 13.0 0.45 10.7 0.7 4.6 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Muted PF14942.6 RUS87591.1 - 0.95 9.8 19.1 0.46 10.8 0.1 4.8 4 2 1 5 5 5 0 Organelle biogenesis, Muted-like protein Cortex-I_coil PF09304.10 RUS87591.1 - 1 9.6 5.3 14 5.9 0.0 4.1 3 1 1 4 4 3 0 Cortexillin I, coiled coil HIP1_clath_bdg PF16515.5 RUS87591.1 - 1.1 9.9 17.8 33 5.2 0.1 6.2 2 2 6 8 8 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 RUS87591.1 - 1.2 9.5 24.0 1.8 9.0 0.5 7.8 6 2 1 9 9 6 0 Csm1 N-terminal domain T3SSipB PF16535.5 RUS87591.1 - 1.5 9.3 12.2 0.1 13.1 2.5 3.1 4 0 0 4 4 2 0 Type III cell invasion protein SipB YscO PF07321.12 RUS87591.1 - 1.9 8.5 4.9 13 5.7 0.2 4.1 3 1 0 4 4 4 0 Type III secretion protein YscO KxDL PF10241.9 RUS87591.1 - 2.2 8.6 14.8 15 5.9 0.0 6.8 2 2 5 9 9 7 0 Uncharacterized conserved protein BRE1 PF08647.11 RUS87591.1 - 2.2 8.4 20.4 17 5.5 0.9 5.9 2 2 4 6 6 6 0 BRE1 E3 ubiquitin ligase CCDC144C PF14915.6 RUS87591.1 - 2.5 7.1 21.2 0.14 11.3 1.1 3.5 2 2 0 2 2 2 0 CCDC144C protein coiled-coil region Snapin_Pallidin PF14712.6 RUS87591.1 - 2.8 8.4 24.6 3.8 8.0 1.0 6.7 2 2 3 6 6 6 0 Snapin/Pallidin Wbp11 PF09429.10 RUS87591.1 - 2.8 8.4 5.9 9.4 6.7 0.5 4.0 4 1 0 4 4 2 0 WW domain binding protein 11 HAUS-augmin3 PF14932.6 RUS87591.1 - 3.1 7.3 16.8 1.6 8.2 2.6 3.8 2 1 2 4 4 4 0 HAUS augmin-like complex subunit 3 CtIP_N PF10482.9 RUS87591.1 - 4.7 7.3 6.9 5.9 7.0 0.2 4.0 2 2 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain ISG65-75 PF11727.8 RUS87591.1 - 5.3 6.2 15.4 0.17 11.1 2.1 3.9 3 2 1 4 4 4 0 Invariant surface glycoprotein DASH_Dam1 PF08653.10 RUS87591.1 - 7.4 6.5 12.2 13 5.7 0.0 6.2 7 1 1 8 8 5 0 DASH complex subunit Dam1 XhlA PF10779.9 RUS87591.1 - 7.6 6.8 24.6 4.8 7.5 0.1 7.3 4 2 3 8 8 8 0 Haemolysin XhlA EF-hand_7 PF13499.6 RUS87592.1 - 1.2e-22 80.2 8.2 5e-09 36.5 0.8 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS87592.1 - 5.7e-21 72.6 6.9 0.0013 18.5 0.0 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 RUS87592.1 - 2.6e-19 67.8 9.0 9.3e-06 24.9 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_1 PF00036.32 RUS87592.1 - 2.8e-19 67.1 12.4 0.00036 19.9 0.0 5.3 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 RUS87592.1 - 6.5e-09 35.5 12.6 0.042 13.7 0.0 5.2 4 2 2 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RUS87592.1 - 0.00019 21.7 0.4 1.4 9.2 0.1 3.1 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 RUS87592.1 - 0.00041 19.0 0.0 0.29 9.6 0.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5580) EF-hand_4 PF12763.7 RUS87592.1 - 0.084 12.8 3.0 1.9 8.5 0.3 3.0 2 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS87592.1 - 0.097 12.6 0.2 5.8 6.8 0.0 2.9 2 1 0 2 2 2 0 Caleosin related protein PAN_1 PF00024.26 RUS87593.1 - 0.21 11.6 8.1 0.88 9.6 8.0 1.9 1 1 0 1 1 1 0 PAN domain PAN_4 PF14295.6 RUS87593.1 - 4.4 7.3 6.9 0.33 10.9 0.8 2.2 2 0 0 2 2 2 0 PAN domain PMT_4TMC PF16192.5 RUS87594.1 - 0.67 9.5 6.8 1.7 8.2 6.8 1.7 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase Amastin PF07344.11 RUS87594.1 - 0.86 9.4 6.5 1.5 8.7 6.5 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein ABC2_membrane_3 PF12698.7 RUS87594.1 - 4.5 6.3 16.3 8 5.5 16.3 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 RUS87594.1 - 5.9 5.5 8.6 76 1.9 8.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 RUS87594.1 - 9.7 6.7 13.4 7.4 7.1 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) M16C_assoc PF08367.11 RUS87595.1 - 6.9e-32 110.5 0.0 1.1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 RUS87595.1 - 3.9e-26 92.2 0.0 7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RUS87595.1 - 8.9e-08 32.2 0.1 8.2e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RUS87596.1 - 5.8e-07 29.7 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain ACT_3 PF10000.9 RUS87596.1 - 0.0022 17.9 0.4 0.0063 16.4 0.1 1.9 2 0 0 2 2 2 1 ACT domain TAS2R PF05296.13 RUS87597.1 - 0.03 13.4 0.2 0.047 12.8 0.2 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) PDZ_5 PF17817.1 RUS87599.1 - 1e-28 99.4 1.3 4.6e-28 97.3 1.3 2.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS87599.1 - 4.4e-13 49.4 0.7 8.8e-13 48.4 0.7 1.5 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 RUS87599.1 - 1.6e-07 31.3 0.2 5.1e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS87599.1 - 1.7e-05 25.2 0.1 3.9e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 RUS87599.1 - 0.0007 19.4 0.2 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 PDZ domain HMMR_N PF15905.5 RUS87599.1 - 0.0032 17.0 23.5 0.0032 17.0 23.5 2.2 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4482 PF14818.6 RUS87599.1 - 0.0084 17.0 0.1 0.0084 17.0 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4482) Cir_Bir_Yir PF06022.11 RUS87599.1 - 0.041 13.4 0.5 0.066 12.7 0.5 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir PDZ_2 PF13180.6 RUS87599.1 - 0.073 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 PDZ domain AAA_23 PF13476.6 RUS87599.1 - 0.08 13.4 18.3 1.1 9.7 10.8 2.4 2 0 0 2 2 2 0 AAA domain Btz PF09405.10 RUS87601.1 - 7e-18 65.1 9.2 7e-18 65.1 9.2 4.3 4 2 1 5 5 5 1 CASC3/Barentsz eIF4AIII binding DUF4606 PF15379.6 RUS87602.1 - 4e-08 33.4 2.2 4e-08 33.4 2.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4606) ADH_zinc_N PF00107.26 RUS87603.1 - 4.8e-25 88.0 0.0 7.5e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS87603.1 - 1.7e-09 38.8 0.0 3.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS87603.1 - 4.4e-08 33.0 1.0 5.8e-07 29.4 0.0 2.9 2 2 2 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS87603.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PGM_PMM_II PF02879.16 RUS87603.1 - 0.15 12.7 0.2 0.48 11.1 0.1 1.9 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Zip PF02535.22 RUS87604.1 - 0.022 14.0 0.1 0.022 14.0 0.1 3.6 1 1 2 3 3 3 0 ZIP Zinc transporter Tim54 PF11711.8 RUS87604.1 - 0.64 8.7 4.8 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 RUS87604.1 - 1.5 9.2 14.0 2.8 8.4 2.3 2.5 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF2207 PF09972.9 RUS87604.1 - 8.2 5.1 24.7 23 3.6 24.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sid-5 PF17204.3 RUS87605.1 - 1.6 8.9 5.0 4.4 7.5 0.7 2.8 2 1 0 2 2 2 0 Sid-5 family DUF603 PF04645.12 RUS87606.1 - 0.016 15.0 0.2 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF3326 PF11805.8 RUS87606.1 - 0.12 11.2 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Secretin_N_2 PF07655.13 RUS87606.1 - 0.55 10.8 25.7 2.5 8.7 8.3 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_C12 PF01088.21 RUS87607.1 - 2.8e-69 233.1 0.0 6.1e-69 232.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 RUS87607.1 - 1.1e-17 63.6 2.7 2.2e-17 62.7 2.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Hemopexin PF00045.19 RUS87608.1 - 1.3e-05 25.0 1.9 0.0025 17.7 0.2 2.9 3 0 0 3 3 3 2 Hemopexin TIR_2 PF13676.6 RUS87609.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 TIR domain Hemopexin PF00045.19 RUS87609.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Hemopexin SET PF00856.28 RUS87611.1 - 1.4e-19 71.1 4.2 8.4e-19 68.6 0.6 3.5 3 1 0 3 3 3 1 SET domain preSET_CXC PF18264.1 RUS87611.1 - 6.7e-11 42.5 15.1 6.7e-11 42.5 15.1 3.9 3 1 1 4 4 4 1 CXC domain PRC2_HTH_1 PF18118.1 RUS87611.1 - 4.7e-10 40.2 11.0 1.2e-07 32.5 0.2 3.8 3 1 1 4 4 4 2 Polycomb repressive complex 2 tri-helical domain SWI-SNF_Ssr4 PF08549.10 RUS87612.1 - 0.007 15.1 2.8 0.0083 14.8 2.8 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) CortBP2 PF09727.9 RUS87612.1 - 0.0089 16.0 5.3 0.012 15.6 5.3 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Lge1 PF11488.8 RUS87612.1 - 0.089 13.0 3.6 0.21 11.8 3.6 1.8 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF4407 PF14362.6 RUS87612.1 - 0.3 10.4 6.1 0.33 10.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRRC37AB_C PF14914.6 RUS87612.1 - 0.92 9.4 4.0 1.1 9.2 3.4 1.3 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TPR_1 PF00515.28 RUS87613.1 - 0.028 14.2 3.2 0.29 11.0 1.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS87613.1 - 0.04 14.0 3.8 0.1 12.8 1.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Lectin_C PF00059.21 RUS87614.1 - 4.8e-06 27.3 0.0 7.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain SDA1 PF05285.12 RUS87615.1 - 0.097 12.1 47.7 0.11 11.9 47.7 1.1 1 0 0 1 1 1 0 SDA1 PAM2 PF07145.15 RUS87617.1 - 0.25 11.1 3.2 0.35 10.7 0.2 2.8 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Collagen PF01391.18 RUS87618.1 - 0.02 14.6 4.3 0.044 13.5 4.3 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) LEDGF PF11467.8 RUS87618.1 - 0.12 12.0 4.3 0.17 11.5 1.4 2.3 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) PE-PPE PF08237.11 RUS87620.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain RhoGAP PF00620.27 RUS87621.1 - 1.3e-29 102.9 0.0 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 RUS87621.1 - 2.1e-29 102.2 0.0 2.1e-29 102.2 0.0 2.8 3 0 0 3 3 3 1 MyTH4 domain Ank_2 PF12796.7 RUS87623.1 - 1.6e-15 57.4 0.0 7.5e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS87623.1 - 1.7e-12 46.3 0.0 6.3e-06 26.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS87623.1 - 1.6e-11 44.1 0.0 1.3e-05 25.4 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RUS87623.1 - 3.1e-11 43.3 0.0 2.1e-07 31.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS87623.1 - 5.7e-11 42.7 0.0 3.7e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ribosomal_S9 PF00380.19 RUS87624.1 - 3e-34 118.1 0.2 3.4e-34 117.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ank_2 PF12796.7 RUS87625.1 - 6.3e-40 135.6 2.6 2.1e-12 47.5 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS87625.1 - 3.1e-25 88.2 0.2 6.3e-11 42.6 0.0 6.4 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS87625.1 - 3.1e-23 81.5 9.4 1.6e-06 28.3 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS87625.1 - 3.6e-21 73.0 3.0 0.0065 16.9 0.0 8.8 8 1 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 RUS87625.1 - 7.8e-21 73.5 4.6 0.0032 17.8 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat RPA43_OB PF17875.1 RUS87626.1 - 2.9e-05 24.7 3.2 9.1e-05 23.1 1.9 2.7 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I DUF3270 PF11674.8 RUS87627.1 - 0.51 10.6 8.4 0.89 9.8 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Pkinase PF00069.25 RUS87628.1 - 1.4e-65 221.3 1.7 2.8e-43 148.2 1.8 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87628.1 - 3e-32 111.9 1.9 2.8e-23 82.5 0.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS87628.1 - 5.7e-06 25.5 0.2 8.2e-06 25.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS87628.1 - 1e-05 25.6 0.2 0.039 13.9 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS87628.1 - 2.9e-05 23.5 0.3 0.0021 17.4 0.1 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 RUS87628.1 - 0.00024 21.7 1.2 0.00066 20.3 1.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 RUS87628.1 - 0.00095 18.6 1.6 0.0029 17.0 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RUS87628.1 - 0.035 13.2 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 RUS87628.1 - 0.047 12.5 1.7 0.096 11.4 1.7 1.6 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RUS87628.1 - 0.097 12.3 0.8 0.24 11.0 0.0 2.0 2 1 0 2 2 2 0 RIO1 family DUF745 PF05335.13 RUS87629.1 - 0.12 12.1 4.1 0.13 11.9 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF745) zf-C3HC4_2 PF13923.6 RUS87630.1 - 1.1e-11 44.3 9.4 1.1e-11 44.3 9.4 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS87630.1 - 1.9e-09 37.3 9.7 1.9e-09 37.3 9.7 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS87630.1 - 2.3e-09 37.4 8.0 2.3e-09 37.4 8.0 3.1 2 1 1 3 3 3 1 Ring finger domain zf-TRAF PF02176.18 RUS87630.1 - 3.2e-09 37.3 22.6 1.5e-05 25.6 9.3 3.6 2 2 1 3 3 3 2 TRAF-type zinc finger zf-RING_UBOX PF13445.6 RUS87630.1 - 2.8e-08 33.6 3.2 2.8e-08 33.6 3.2 3.0 2 2 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RUS87630.1 - 9.9e-08 31.7 8.1 9.9e-08 31.7 8.1 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS87630.1 - 3.1e-07 30.2 8.3 3.1e-07 30.2 8.3 3.3 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS87630.1 - 5.5e-06 26.1 7.1 5.5e-06 26.1 7.1 3.2 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 RUS87630.1 - 1.2e-05 25.1 2.6 1.2e-05 25.1 2.6 2.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 RUS87630.1 - 2.7e-05 24.2 8.1 2.7e-05 24.2 8.1 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 RUS87630.1 - 8e-05 22.9 7.5 8e-05 22.9 7.5 3.9 2 2 0 2 2 1 1 RING-H2 zinc finger domain Sina PF03145.16 RUS87630.1 - 0.0012 18.9 15.0 0.067 13.1 6.9 2.2 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_10 PF16685.5 RUS87630.1 - 0.0018 18.3 6.9 0.0018 18.3 6.9 3.2 1 1 2 3 3 2 1 zinc RING finger of MSL2 zf-CCCH_8 PF18633.1 RUS87630.1 - 0.0043 17.1 0.2 0.029 14.5 0.2 2.4 1 0 0 1 1 1 1 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 zf-ANAPC11 PF12861.7 RUS87630.1 - 0.012 15.6 1.2 0.012 15.6 1.2 3.0 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_4 PF13717.6 RUS87630.1 - 0.077 12.9 9.1 0.32 10.9 0.5 4.0 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 RUS87630.1 - 4.7 7.5 27.2 0.068 13.4 9.5 3.6 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Rep_fac-A_C PF08646.10 RUS87630.1 - 6 6.6 14.5 2.2 8.0 7.6 2.1 1 1 1 2 2 2 0 Replication factor-A C terminal domain MIF4G PF02854.19 RUS87631.1 - 9.6e-52 175.7 6.2 9.6e-52 175.7 6.2 2.2 3 0 0 3 3 3 1 MIF4G domain W2 PF02020.18 RUS87631.1 - 2.4e-19 69.2 1.7 8.2e-19 67.5 1.7 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.17 RUS87631.1 - 1.9e-07 31.1 2.0 1.7e-05 24.8 0.0 3.4 3 0 0 3 3 3 1 MA3 domain eIF3_p135 PF12807.7 RUS87631.1 - 0.012 15.6 0.8 0.043 13.9 0.4 2.0 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 KIP1 PF07765.12 RUS87631.1 - 1.4 9.1 6.0 0.48 10.6 0.2 3.3 3 0 0 3 3 3 0 KIP1-like protein GRP PF07172.11 RUS87631.1 - 2.3 9.0 12.8 7.5 7.3 12.8 1.9 1 0 0 1 1 1 0 Glycine rich protein family Tetraspanin PF00335.20 RUS87632.1 - 4e-17 62.7 17.4 1.2e-09 38.2 4.5 2.1 1 1 1 2 2 2 2 Tetraspanin family K1 PF02960.14 RUS87632.1 - 0.0033 17.5 0.3 0.0071 16.4 0.2 1.6 1 1 0 1 1 1 1 K1 glycoprotein 7TM_GPCR_Srx PF10328.9 RUS87634.1 - 0.00054 19.7 14.8 0.00054 19.7 14.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS87634.1 - 0.14 11.4 11.1 0.091 12.1 9.8 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1761 PF08570.10 RUS87634.1 - 0.23 11.8 5.2 0.19 12.0 3.7 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) TcpE PF12648.7 RUS87634.1 - 3.9 8.0 8.6 0.32 11.6 3.0 1.9 1 1 1 2 2 2 0 TcpE family Asp PF00026.23 RUS87636.1 - 2.2e-123 411.7 0.6 2.7e-123 411.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RUS87636.1 - 1.1e-15 58.3 0.4 1e-13 51.9 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RUS87636.1 - 0.00051 20.6 0.2 1.7 9.3 0.0 3.7 3 1 0 3 3 3 2 Aspartyl protease A1_Propeptide PF07966.12 RUS87636.1 - 0.018 14.9 0.6 0.033 14.1 0.6 1.4 1 0 0 1 1 1 0 A1 Propeptide Asp PF00026.23 RUS87637.1 - 7.3e-115 383.7 0.0 9e-115 383.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RUS87637.1 - 9.4e-16 58.6 0.1 3.1e-13 50.4 0.1 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RUS87637.1 - 8.3e-05 23.2 0.0 0.29 11.8 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 RUS87637.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal RPE65 PF03055.15 RUS87638.1 - 1.4e-83 281.6 0.0 1.7e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RT_RNaseH_2 PF17919.1 RUS87639.1 - 1.5e-32 111.6 0.0 4e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS87639.1 - 3.9e-26 91.4 0.0 9.4e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS87639.1 - 2.7e-16 59.8 0.0 7.5e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS87639.1 - 5.7e-15 55.2 0.1 5.7e-15 55.2 0.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 RUS87639.1 - 0.00012 21.7 0.0 0.00031 20.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 RUS87639.1 - 0.011 16.3 0.0 0.03 14.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS87639.1 - 0.018 15.7 0.0 0.042 14.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 RUS87639.1 - 0.02 15.1 0.6 0.11 12.7 0.0 2.7 3 0 0 3 3 3 0 H2C2 zinc finger LMBR1 PF04791.16 RUS87639.1 - 5.5 5.8 6.0 3.5 6.4 2.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein RPE65 PF03055.15 RUS87640.1 - 3.5e-97 326.5 0.0 4.4e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MH1 PF03165.16 RUS87641.1 - 1.6e-25 89.3 0.5 2.3e-25 88.8 0.5 1.2 1 0 0 1 1 1 1 MH1 domain Torus PF16131.5 RUS87642.1 - 8.4e-06 26.4 0.3 1.7e-05 25.4 0.3 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 RUS87642.1 - 9.9e-06 25.2 7.6 1.7e-05 24.5 7.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger RasGEF PF00617.19 RUS87643.1 - 5.3e-47 160.3 0.1 2.3e-46 158.2 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 RUS87643.1 - 4e-28 97.7 0.1 9.1e-28 96.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 RUS87643.1 - 4.7e-15 56.3 0.3 4.1e-14 53.2 0.0 2.7 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 RUS87643.1 - 5.8e-09 36.4 0.0 1.6e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Histone PF00125.24 RUS87643.1 - 7.3e-06 26.4 0.0 2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.6 RUS87643.1 - 6.3e-05 23.2 0.0 0.0003 21.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain LRR_6 PF13516.6 RUS87644.1 - 0.0021 17.9 0.3 17 5.7 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 RUS87644.1 - 0.062 13.7 0.5 5.8 7.5 0.1 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS87644.1 - 0.071 13.7 0.4 4.2 8.3 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat PSII_BNR PF14870.6 RUS87644.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 LRR_8 PF13855.6 RUS87644.1 - 0.2 11.5 1.0 0.5 10.2 0.1 2.1 2 1 1 3 3 3 0 Leucine rich repeat Suf PF05843.14 RUS87646.1 - 2.1e-09 37.8 10.2 6.2e-05 23.1 0.2 3.6 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 RUS87646.1 - 2.7e-09 37.0 0.2 0.19 12.7 0.0 7.0 4 2 4 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 RUS87646.1 - 3e-05 23.3 0.4 3e-05 23.3 0.4 3.1 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 RUS87646.1 - 0.0022 17.2 1.8 1.8 7.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS87646.1 - 0.0053 17.2 0.1 2.2 8.9 0.0 3.5 4 1 1 5 5 4 1 Tetratricopeptide repeat PHINT_rpt PF14882.6 RUS87646.1 - 0.024 14.9 4.0 6.5 7.1 0.1 3.9 3 0 0 3 3 3 0 Phage-integrase repeat unit Mad3_BUB1_I PF08311.12 RUS87646.1 - 0.043 13.8 14.3 3.5 7.6 0.2 5.9 5 2 0 5 5 5 0 Mad3/BUB1 homology region 1 zf-C2H2_12 PF18658.1 RUS87646.1 - 0.081 12.5 0.3 0.26 10.9 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type DUF3741 PF12552.8 RUS87646.1 - 0.11 12.4 0.3 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) TPR_8 PF13181.6 RUS87646.1 - 0.77 10.1 6.5 17 5.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS87646.1 - 1.1 9.5 4.1 7.1 7.0 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 RUS87647.1 - 6.2e-66 222.5 0.0 1.1e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87647.1 - 5.1e-38 130.8 0.0 7.7e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RUS87647.1 - 1.2e-31 108.3 25.8 6.3e-16 58.0 5.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 RUS87647.1 - 3.2e-13 49.8 0.1 7.4e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 RUS87647.1 - 7.5e-11 42.6 1.4 1.7e-10 41.4 1.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RUS87647.1 - 0.0015 18.0 0.0 0.0035 16.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RUS87647.1 - 0.003 17.5 0.1 0.021 14.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family C1_2 PF03107.16 RUS87647.1 - 0.0082 16.4 16.9 0.45 10.9 5.5 2.7 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 RUS87647.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zf_RING PF16744.5 RUS87647.1 - 0.013 15.6 14.1 0.13 12.4 5.0 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Haspin_kinase PF12330.8 RUS87647.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 RUS87647.1 - 0.07 13.1 16.8 0.67 9.9 2.4 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FTA2 PF13095.6 RUS87647.1 - 0.076 12.6 0.3 2.5 7.7 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PHD PF00628.29 RUS87647.1 - 2.8 7.9 22.9 1.2 9.1 5.7 2.5 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 RUS87647.1 - 9.3 6.4 12.7 5.2 7.2 0.7 2.7 3 0 0 3 3 2 0 PHD-finger 2OG-FeII_Oxy_3 PF13640.6 RUS87648.1 - 2.4e-09 38.0 0.0 5.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MIT PF04212.18 RUS87648.1 - 0.0006 19.8 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain 2OG-FeII_Oxy_5 PF13759.6 RUS87648.1 - 0.051 14.0 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Pox_C4_C10 PF03336.13 RUS87648.1 - 0.051 12.7 0.0 0.52 9.4 0.0 2.4 3 1 1 4 4 4 0 Poxvirus C4/C10 protein HECT PF00632.25 RUS87649.1 - 7.6e-74 248.9 0.0 1.4e-73 248.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 RUS87649.1 - 2.3e-21 75.8 3.3 7.7e-21 74.1 3.3 2.0 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.13 RUS87649.1 - 7.8e-18 64.8 0.0 5.1e-17 62.1 0.0 2.3 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal Ank_5 PF13857.6 RUS87649.1 - 2.6e-10 40.3 0.0 2.9e-05 24.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS87649.1 - 4.6e-10 39.9 0.0 1.8e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS87649.1 - 1.8e-07 30.9 0.0 0.032 14.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS87649.1 - 1e-06 28.9 0.0 0.00044 20.6 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat F5_F8_type_C PF00754.25 RUS87649.1 - 4.1e-05 23.7 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain Ank_4 PF13637.6 RUS87649.1 - 0.00016 22.1 0.0 0.044 14.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RTP1_C1 PF10363.9 RUS87649.1 - 0.062 13.5 0.8 1.6 9.0 0.0 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 NOA36 PF06524.12 RUS87649.1 - 1.7 7.9 10.7 3.5 6.9 10.7 1.4 1 0 0 1 1 1 0 NOA36 protein DcpS_C PF11969.8 RUS87651.1 - 0.078 13.5 0.8 0.34 11.4 0.3 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RUS87651.1 - 0.17 12.6 2.2 1.2 9.9 2.2 2.3 1 1 0 1 1 1 0 HIT domain HMMR_C PF15908.5 RUS87652.1 - 0.066 13.5 9.2 0.39 11.0 9.3 2.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DivIC PF04977.15 RUS87652.1 - 1.2 8.9 5.4 4.9 7.0 0.0 3.0 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 RUS87652.1 - 1.6 8.8 15.2 2.4 8.2 14.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 RUS87652.1 - 8.4 7.2 9.2 11 6.7 0.6 2.9 1 1 2 3 3 3 0 Occludin homology domain DUF3742 PF12553.8 RUS87653.1 - 2.7 8.1 4.7 0.41 10.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) ApoLp-III PF07464.11 RUS87654.1 - 6.4 6.9 8.2 0.61 10.2 1.1 2.8 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) CBM9_1 PF06452.11 RUS87655.1 - 0.03 14.2 0.1 0.77 9.6 0.1 2.5 2 0 0 2 2 2 0 Carbohydrate family 9 binding domain-like zf-C2H2 PF00096.26 RUS87656.1 - 9.1e-25 85.7 134.4 0.00042 20.6 0.4 17.5 17 0 0 17 17 17 13 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS87656.1 - 6.5e-20 70.6 121.5 3.4e-06 27.2 2.3 15.9 16 1 0 16 16 15 9 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS87656.1 - 3.9e-16 58.3 130.2 0.032 15.1 1.5 17.8 18 0 0 18 18 18 10 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS87656.1 - 1.6e-05 25.1 64.4 0.0037 17.5 2.6 8.5 3 2 6 9 9 9 6 C2H2-type zinc ribbon zf-Di19 PF05605.12 RUS87656.1 - 0.0051 17.1 3.3 0.0051 17.1 3.3 9.7 8 3 4 12 12 11 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS87656.1 - 0.039 14.3 46.3 1.3 9.5 0.6 10.9 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS87656.1 - 0.094 13.0 0.2 0.094 13.0 0.2 14.2 15 0 0 15 15 15 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 RUS87656.1 - 0.11 12.2 0.1 0.11 12.2 0.1 6.9 8 0 0 8 8 8 0 C2H2 Hakai zinc finger domain MerB PF03243.15 RUS87656.1 - 0.16 12.1 4.7 0.47 10.6 0.2 2.9 3 0 0 3 3 3 0 Alkylmercury lyase zinc_ribbon_5 PF13719.6 RUS87656.1 - 0.45 10.3 10.6 0.28 11.0 0.1 4.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 RUS87656.1 - 0.82 9.7 8.8 15 5.6 0.2 4.5 4 0 0 4 4 4 0 zinc-ribbon domain ERO1 PF04137.15 RUS87657.1 - 1.5e-126 422.4 0.4 1.8e-126 422.1 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) tRNA-synt_1 PF00133.22 RUS87660.1 - 1.3e-153 512.4 1.0 1.7e-153 512.1 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RUS87660.1 - 4.1e-24 85.3 0.0 8.9e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RUS87660.1 - 1.7e-22 79.7 3.3 8e-17 61.1 0.1 3.7 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RUS87660.1 - 6.5e-07 29.0 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 RUS87660.1 - 0.0041 16.5 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RAB3GAP2_C PF14656.6 RUS87661.1 - 1.9e-154 515.2 7.4 3.2e-154 514.5 7.4 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 RUS87661.1 - 1.7e-141 472.3 0.0 2.5e-141 471.7 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Lectin_C PF00059.21 RUS87662.1 - 0.011 16.4 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Lectin C-type domain MULE PF10551.9 RUS87663.1 - 0.031 14.7 0.3 0.042 14.3 0.3 1.2 1 0 0 1 1 1 0 MULE transposase domain Abhydrolase_3 PF07859.13 RUS87664.1 - 5.7e-46 157.0 0.0 6.9e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 RUS87664.1 - 1.6e-05 24.6 0.0 0.00019 21.1 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.28 RUS87664.1 - 0.00043 19.3 0.3 0.0024 16.8 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 RUS87664.1 - 0.0022 17.6 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 RUS87664.1 - 0.011 15.0 0.0 0.11 11.7 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Skp1_POZ PF03931.15 RUS87664.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Peptidase_S9 PF00326.21 RUS87664.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family Myb_DNA-binding PF00249.31 RUS87665.1 - 8.5e-06 25.9 0.1 5.4e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS87665.1 - 0.022 15.0 0.1 0.15 12.4 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain PRTase_3 PF15610.6 RUS87665.1 - 0.058 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like SnAPC_2_like PF11035.8 RUS87665.1 - 0.07 13.3 6.1 0.11 12.6 0.2 2.9 2 1 1 3 3 3 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb PPPI_inhib PF14895.6 RUS87666.1 - 1.7e-33 116.2 0.0 8.2e-33 114.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 1 inhibitor DUF3408 PF11888.8 RUS87666.1 - 2.2 8.4 8.8 6.4 6.9 2.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) Proteasome PF00227.26 RUS87667.1 - 7.3e-54 182.1 0.3 1.1e-53 181.6 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS87667.1 - 5.1e-13 48.4 0.3 9.6e-13 47.6 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TMEM171 PF15471.6 RUS87668.1 - 0.049 12.6 1.3 0.08 11.9 0.8 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 CAP_N PF01213.19 RUS87668.1 - 0.64 9.4 3.1 0.91 8.9 3.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-C4 PF00105.18 RUS87669.1 - 7.3e-24 84.0 16.3 2.6e-23 82.3 16.3 2.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) PLDc_3 PF13918.6 RUS87670.1 - 1.4e-34 119.3 0.0 2e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 RUS87670.1 - 1.5e-20 73.4 0.6 4.6e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RUS87670.1 - 5.3e-14 51.7 5.2 8.9e-08 32.0 0.5 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif GRIP PF01465.20 RUS87671.1 - 2.6e-17 62.5 0.0 6.5e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 GRIP domain Golgin_A5 PF09787.9 RUS87671.1 - 0.00022 20.8 91.7 0.0021 17.6 8.6 5.7 2 1 2 5 5 5 4 Golgin subfamily A member 5 Transposase_1 PF01359.18 RUS87671.1 - 0.012 15.4 0.1 0.059 13.2 0.1 2.2 1 0 0 1 1 1 0 Transposase (partial DDE domain) DUF4174 PF13778.6 RUS87671.1 - 0.017 15.6 1.4 0.017 15.6 1.4 4.3 4 2 0 4 4 4 0 Domain of unknown function (DUF4174) KAR PF15222.6 RUS87671.1 - 0.064 13.6 3.0 1.9 8.8 0.9 3.3 2 1 0 2 2 2 0 Kidney androgen-regulated Homeodomain PF00046.29 RUS87672.1 - 2e-23 82.0 2.1 4.2e-23 80.9 2.1 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS87672.1 - 0.0012 18.6 0.1 0.0045 16.8 0.1 2.1 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 RUS87672.1 - 0.0066 16.3 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain OAR PF03826.17 RUS87673.1 - 2e-05 24.3 4.1 4e-05 23.3 4.1 1.6 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 RUS87673.1 - 5.9e-05 22.8 1.3 0.00012 21.9 1.3 1.5 1 0 0 1 1 1 1 Homeodomain 7tm_1 PF00001.21 RUS87674.1 - 1.7e-07 30.9 19.5 1.7e-07 30.9 19.5 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87674.1 - 0.00026 20.7 24.9 0.00026 20.7 24.9 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Srg PF02118.21 RUS87674.1 - 0.0057 16.4 19.7 0.0057 16.4 19.7 2.3 2 0 0 2 2 2 1 Srg family chemoreceptor Pribosyl_synth PF14572.6 RUS87676.1 - 1.2e-37 129.8 0.6 1.3e-37 129.6 0.6 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RUS87676.1 - 2.1e-06 27.3 0.8 2.7e-06 27.0 0.7 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RUS87676.1 - 0.0011 18.4 0.3 0.0013 18.2 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 RUS87676.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C AAA_11 PF13086.6 RUS87677.1 - 2.1e-58 198.1 1.0 2.1e-58 198.1 1.0 3.7 2 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 RUS87677.1 - 9.2e-54 182.1 0.1 4.2e-53 179.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS87677.1 - 2e-15 57.0 2.1 8.9e-13 48.4 2.1 3.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RUS87677.1 - 2.7e-10 40.8 0.2 2.5e-09 37.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RUS87677.1 - 2.4e-09 37.3 0.1 0.12 12.1 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase zf-AN1 PF01428.16 RUS87677.1 - 6.4e-08 32.6 5.1 6.4e-08 32.6 5.1 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger Helicase_RecD PF05127.14 RUS87677.1 - 1.3e-06 28.4 0.4 0.00082 19.3 0.3 3.3 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 RUS87677.1 - 1.3e-06 28.5 0.0 6.1e-06 26.3 0.0 2.0 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 RUS87677.1 - 9.1e-05 22.1 0.9 0.0086 15.7 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RUS87677.1 - 0.00011 22.5 1.2 0.0014 18.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RUS87677.1 - 0.00017 21.0 1.3 0.19 11.0 0.0 3.6 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 RUS87677.1 - 0.00028 21.3 0.4 0.00028 21.3 0.4 2.2 2 0 0 2 2 1 1 AAA ATPase domain DEAD PF00270.29 RUS87677.1 - 0.00039 20.2 2.6 0.0042 16.9 0.2 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 RUS87677.1 - 0.0022 18.0 1.6 0.045 13.7 0.1 3.1 3 0 0 3 3 3 1 Flavivirus DEAD domain IstB_IS21 PF01695.17 RUS87677.1 - 0.0025 17.6 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein UvrD_C_2 PF13538.6 RUS87677.1 - 0.0031 17.3 0.1 0.008 16.0 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 RUS87677.1 - 0.0034 16.5 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 RUS87677.1 - 0.0037 16.8 2.9 0.0046 16.5 0.2 2.3 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 RUS87677.1 - 0.004 17.6 0.5 0.017 15.6 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Glycos_transf_2 PF00535.26 RUS87677.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 PIF1 PF05970.14 RUS87677.1 - 0.013 14.7 0.0 0.62 9.2 0.0 2.9 2 1 0 2 2 2 0 PIF1-like helicase CobA_CobO_BtuR PF02572.15 RUS87677.1 - 0.015 15.5 0.1 6 7.1 0.0 2.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Zot PF05707.12 RUS87677.1 - 0.017 14.8 0.1 0.12 12.0 0.0 2.2 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) SRP54 PF00448.22 RUS87677.1 - 0.025 14.2 0.2 0.93 9.1 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 RUS87677.1 - 0.03 13.7 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 KaiC cobW PF02492.19 RUS87677.1 - 0.041 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 RUS87677.1 - 0.043 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 RUS87677.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyco_tranf_2_3 PF13641.6 RUS87677.1 - 0.047 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ABC_tran PF00005.27 RUS87677.1 - 0.057 13.9 0.1 0.29 11.6 0.1 2.3 1 1 0 1 1 1 0 ABC transporter Glyco_transf_21 PF13506.6 RUS87677.1 - 0.089 12.3 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Herpes_Helicase PF02689.14 RUS87677.1 - 0.1 10.5 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 RUS87677.1 - 0.18 11.7 1.3 1.8 8.4 0.6 2.6 2 0 0 2 2 2 0 NTPase PIH1_CS PF18201.1 RUS87678.1 - 1e-13 51.5 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain Gal-3-0_sulfotr PF06990.11 RUS87680.1 - 0.069 12.0 0.0 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase Glucos_trans_II PF14264.6 RUS87680.1 - 0.22 10.8 4.3 3.3 7.0 0.3 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII zf-A20 PF01754.16 RUS87681.1 - 1.6e-09 37.5 8.1 1.6e-09 37.5 8.1 2.3 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 RUS87681.1 - 0.00022 21.3 6.0 0.00022 21.3 6.0 2.1 2 1 0 2 2 2 1 AN1-like Zinc finger RAP1 PF07218.11 RUS87681.1 - 0.64 8.2 11.5 0.88 7.8 11.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S6 PF01250.17 RUS87683.1 - 0.011 16.0 0.0 0.07 13.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S6 CCCAP PF15964.5 RUS87685.1 - 9.7e-19 67.1 68.3 9.7e-19 67.1 68.3 3.8 3 1 2 5 5 5 1 Centrosomal colon cancer autoantigen protein family CENP-F_leu_zip PF10473.9 RUS87685.1 - 0.0057 16.7 11.3 0.0057 16.7 11.3 8.3 3 1 3 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 RUS87685.1 - 0.021 15.0 39.1 1.4 9.2 2.8 7.5 6 2 0 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 RUS87685.1 - 0.024 15.3 2.2 0.024 15.3 2.2 8.6 4 2 6 10 10 10 0 Bacterial protein of unknown function (DUF883) TolA_bind_tri PF16331.5 RUS87685.1 - 0.024 14.7 1.3 0.024 14.7 1.3 8.6 5 3 3 8 8 8 0 TolA binding protein trimerisation DUF4407 PF14362.6 RUS87685.1 - 0.043 13.2 69.4 0.094 12.0 10.2 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 RUS87685.1 - 0.12 12.8 0.3 0.12 12.8 0.3 10.2 8 4 4 12 12 12 0 Flagella accessory protein C (FlaC) Bap31_Bap29_C PF18035.1 RUS87685.1 - 0.13 12.3 0.1 0.13 12.3 0.1 8.6 7 2 0 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain zf-C2H2 PF00096.26 RUS87686.1 - 1.7e-15 56.5 35.0 6.6e-05 23.1 4.0 6.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS87686.1 - 7.5e-13 48.3 33.2 1.4e-05 25.3 0.4 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf_Hakai PF18408.1 RUS87686.1 - 3.4e-05 23.4 0.9 3.4e-05 23.4 0.9 4.1 4 0 0 4 4 4 1 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 RUS87686.1 - 0.011 16.5 0.9 0.011 16.5 0.9 6.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS87686.1 - 4.9 7.6 21.7 0.29 11.5 0.4 4.5 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding TFIIB PF00382.19 RUS87687.1 - 4.6e-08 33.0 0.0 4.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat zf-ribbon_3 PF13248.6 RUS87687.1 - 0.00024 20.4 14.0 0.98 8.9 0.1 5.8 4 1 0 5 5 5 3 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 RUS87687.1 - 0.00038 19.9 22.8 0.0013 18.2 0.8 4.1 3 1 1 4 4 4 2 TFIIB zinc-binding Lar_restr_allev PF14354.6 RUS87687.1 - 0.0014 19.0 15.7 0.033 14.6 0.2 3.7 3 1 1 4 4 4 2 Restriction alleviation protein Lar Rsm1 PF08600.10 RUS87687.1 - 0.045 13.9 0.1 6.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Rsm1-like TFIIB_C_1 PF18542.1 RUS87687.1 - 0.17 11.9 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 DZR PF12773.7 RUS87687.1 - 0.22 11.6 26.8 0.61 10.2 7.7 4.4 3 2 1 4 4 4 0 Double zinc ribbon Ribosomal_S27e PF01667.17 RUS87687.1 - 0.58 9.9 12.6 1.8 8.3 1.4 3.8 3 0 0 3 3 3 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.10 RUS87687.1 - 1.8 8.8 24.2 3.1 8.0 1.4 4.8 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 RUS87687.1 - 3.9 7.3 21.6 0.047 13.4 3.3 4.5 5 0 0 5 5 5 0 zinc-ribbon domain Nudix_N_2 PF14803.6 RUS87687.1 - 6.4 6.8 18.9 4.3 7.3 0.7 4.6 4 0 0 4 4 4 0 Nudix N-terminal Glyco_hydro_15 PF00723.21 RUS87688.1 - 2.4e-151 504.6 0.0 7.7e-151 502.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 PIN_3 PF13470.6 RUS87688.1 - 0.1 13.3 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 PIN domain Cyt-b5 PF00173.28 RUS87689.1 - 1.1e-14 54.3 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hepcidin PF06446.12 RUS87691.1 - 0.032 14.6 4.7 0.12 12.8 4.7 1.9 1 0 0 1 1 1 0 Hepcidin Glutaredoxin PF00462.24 RUS87691.1 - 0.094 12.9 0.0 0.094 12.9 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Abi_HHR PF07815.14 RUS87692.1 - 3.7e-28 97.5 0.1 7.1e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_9 PF14604.6 RUS87692.1 - 1.7e-17 63.0 0.1 5e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RUS87692.1 - 3.3e-15 55.4 0.1 5.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RUS87692.1 - 5.1e-13 48.5 0.0 1.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 RUS87693.1 - 5.8e-27 93.4 31.8 2.5e-06 28.1 0.3 11.9 14 0 0 14 14 13 4 WD domain, G-beta repeat Utp12 PF04003.12 RUS87693.1 - 8.3e-22 77.5 0.4 1.6e-21 76.6 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RUS87693.1 - 3.4e-20 72.1 1.8 0.038 14.3 0.0 9.2 5 3 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS87693.1 - 1.9e-07 30.4 1.1 1.5 7.7 0.0 7.0 4 3 3 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS87693.1 - 1.1e-05 25.4 0.6 0.0087 16.0 0.1 4.2 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RUS87693.1 - 0.00023 21.0 0.0 29 4.7 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 RUS87693.1 - 0.0012 18.3 0.2 1.7 7.9 0.0 2.8 4 0 0 4 4 4 2 WD40-like domain PALB2_WD40 PF16756.5 RUS87693.1 - 0.0018 17.3 0.2 0.023 13.6 0.0 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 RUS87693.1 - 0.0077 15.4 0.1 1.9 7.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 RUS87693.1 - 0.032 13.9 5.2 1.5 8.5 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 RUS87693.1 - 0.045 13.1 0.0 0.47 9.7 0.0 2.5 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal OST3_OST6 PF04756.13 RUS87695.1 - 1.2e-109 366.2 0.4 1.6e-109 365.8 0.4 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 RUS87695.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Plant_vir_prot PF01307.17 RUS87695.1 - 0.21 11.8 0.7 2.1 8.6 0.0 2.9 4 1 1 5 5 5 0 Plant viral movement protein Gram_pos_anchor PF00746.21 RUS87695.1 - 0.67 10.0 5.6 0.3 11.1 0.5 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Yip1 PF04893.17 RUS87695.1 - 3.1 7.5 9.0 0.079 12.7 1.4 2.1 2 1 0 2 2 2 0 Yip1 domain CoaE PF01121.20 RUS87696.1 - 8.6e-60 201.5 0.0 1e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 RUS87696.1 - 9.2e-05 23.0 0.1 0.00037 21.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 RUS87696.1 - 0.00027 21.1 0.2 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.6 RUS87696.1 - 0.00092 19.6 0.2 0.011 16.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS87696.1 - 0.0037 17.4 0.0 0.012 15.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 RUS87696.1 - 0.01 16.0 0.4 4.5 7.4 0.1 2.3 2 1 0 2 2 2 0 Cytidylate kinase-like family dNK PF01712.19 RUS87696.1 - 0.019 14.9 0.2 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 RUS87696.1 - 0.075 13.3 0.2 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RUS87696.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase MCM_lid PF17855.1 RUS87697.1 - 1.9e-08 34.6 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain zf-C3HC4_5 PF17121.5 RUS87697.1 - 0.14 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCM_OB PF17207.3 RUS87698.1 - 0.0051 16.7 1.3 0.035 14.0 1.3 2.2 1 1 0 1 1 1 1 MCM OB domain TF_Zn_Ribbon PF08271.12 RUS87698.1 - 0.12 11.9 1.2 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Tetraspanin PF00335.20 RUS87699.1 - 2.5e-16 60.1 3.3 3.1e-16 59.8 3.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3180 PF11377.8 RUS87699.1 - 0.0024 18.0 4.0 0.0034 17.5 3.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3180) Abhydrolase_9_N PF15420.6 RUS87699.1 - 0.0062 16.6 2.6 0.01 15.9 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus TctB PF07331.11 RUS87699.1 - 0.02 15.2 7.6 0.043 14.1 7.6 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Pox_LP_H2 PF03356.15 RUS87699.1 - 0.041 13.8 2.0 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 Viral late protein H2 DUF4271 PF14093.6 RUS87699.1 - 0.075 12.9 8.2 0.095 12.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PIG-Y PF15159.6 RUS87699.1 - 0.18 12.7 8.1 0.65 11.0 6.3 2.4 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y EMP70 PF02990.16 RUS87699.1 - 0.34 9.5 6.0 0.41 9.3 6.0 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 EI24 PF07264.11 RUS87699.1 - 1 9.6 8.6 2.2 8.5 8.6 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) NS3_envE PF02723.14 RUS87699.1 - 1.2 9.3 9.2 0.14 12.3 1.1 2.5 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF4131 PF13567.6 RUS87699.1 - 5.7 6.6 7.5 0.7 9.5 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Arf PF00025.21 RUS87701.1 - 8e-38 129.6 0.0 1.4e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RUS87701.1 - 7.1e-09 35.3 0.0 7.2e-07 28.7 0.0 2.6 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 RUS87701.1 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS87701.1 - 6.8e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RUS87701.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS87701.1 - 0.00038 19.9 0.0 0.00083 18.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS87701.1 - 0.022 14.8 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ASC PF00858.24 RUS87702.1 - 8.2e-10 38.2 0.1 9e-10 38.1 0.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3341 PF11821.8 RUS87702.1 - 6.2e-05 22.7 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) CARD_2 PF16739.5 RUS87702.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Caspase recruitment domain PT PF04886.12 RUS87703.1 - 2.4e-24 84.6 77.4 6.4e-06 25.6 7.6 7.4 3 3 3 6 6 6 6 PT repeat GlutR_dimer PF00745.20 RUS87703.1 - 0.29 11.6 13.8 20 5.7 0.4 5.4 1 1 3 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain TSC21 PF15217.6 RUS87703.1 - 0.78 9.7 10.4 0.15 12.0 1.1 2.3 1 1 1 2 2 2 0 TSC21 family MIF PF01187.18 RUS87703.1 - 8.2 6.8 11.9 3.1 8.1 0.5 3.5 1 1 1 2 2 2 0 Macrophage migration inhibitory factor (MIF) ASC PF00858.24 RUS87704.1 - 8.9e-43 146.9 0.7 1e-42 146.7 0.7 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF1487 PF07368.11 RUS87704.1 - 0.19 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ASC PF00858.24 RUS87705.1 - 2.4e-65 221.2 1.6 2.8e-65 221.0 1.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel MitoNEET_N PF10660.9 RUS87705.1 - 0.15 12.1 0.3 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3341 PF11821.8 RUS87705.1 - 0.17 11.5 0.3 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Tim17 PF02466.19 RUS87705.1 - 0.69 10.3 0.1 0.69 10.3 0.1 2.2 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S4e PF00900.20 RUS87706.1 - 1.9e-35 120.6 0.2 4.3e-35 119.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 RUS87706.1 - 8.2e-27 92.6 0.0 1.8e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 RUS87706.1 - 3.9e-17 62.1 3.5 1e-16 60.8 3.5 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 RUS87706.1 - 4e-07 29.7 0.5 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 RUS87706.1 - 1.8e-06 27.7 0.5 1.8e-06 27.7 0.5 2.2 2 0 0 2 2 2 1 KOW motif Amelogenin PF02948.15 RUS87707.1 - 0.32 11.6 54.8 2.6 8.6 17.2 3.4 1 1 2 3 3 3 0 Amelogenin PKD_channel PF08016.12 RUS87708.1 - 0.00041 19.1 3.9 0.00056 18.7 3.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel PKD_channel PF08016.12 RUS87709.1 - 6.1e-10 38.4 0.1 6.4e-10 38.3 0.1 1.0 1 0 0 1 1 1 1 Polycystin cation channel CBM49 PF09478.10 RUS87709.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 DUF420 PF04238.12 RUS87710.1 - 0.27 11.5 9.1 0.25 11.6 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF420) EI24 PF07264.11 RUS87710.1 - 8.4 6.6 12.7 13 6.0 12.7 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) LRR_5 PF13306.6 RUS87711.1 - 0.17 11.8 1.9 0.25 11.3 1.9 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) CDCA PF18484.1 RUS87711.1 - 0.93 9.3 3.9 9 6.1 0.7 2.0 1 1 1 2 2 2 0 Cadmium carbonic anhydrase repeat TIL PF01826.17 RUS87711.1 - 6.7 7.0 29.4 3.8 7.8 9.9 2.7 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF685 PF05085.12 RUS87713.1 - 1.6 8.0 4.4 11 5.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF685) DUF3947 PF13135.6 RUS87713.1 - 5.7 7.2 12.2 8.6 6.6 1.8 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3947) Nop14 PF04147.12 RUS87714.1 - 0.052 11.8 13.2 0.062 11.5 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family REJ PF02010.15 RUS87714.1 - 0.058 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 REJ domain DNA_pol_phi PF04931.13 RUS87714.1 - 0.19 9.8 26.9 0.24 9.4 26.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 RUS87714.1 - 1.7 8.0 15.7 2.3 7.6 15.7 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RUS87714.1 - 3 7.4 9.9 3.8 7.0 9.9 1.2 1 0 0 1 1 1 0 PPP4R2 Thioredoxin_8 PF13905.6 RUS87715.1 - 3.9e-17 62.4 0.0 1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like LRR_8 PF13855.6 RUS87715.1 - 8.9e-11 41.4 4.8 2.2e-08 33.7 0.8 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS87715.1 - 8.3e-09 35.6 11.5 1.2e-07 31.9 2.1 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS87715.1 - 9.2e-07 28.6 4.1 1.3 9.8 0.1 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRRNT PF01462.18 RUS87715.1 - 4.5e-06 26.2 0.6 1.8e-05 24.2 0.6 2.1 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 RUS87715.1 - 1.6e-05 24.6 8.5 0.065 13.3 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_5 PF13306.6 RUS87715.1 - 0.00033 20.6 1.0 0.00099 19.1 0.1 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Thioredoxin PF00085.20 RUS87715.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 RUS87715.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 RUS87715.1 - 0.054 13.4 0.8 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family RRM_1 PF00076.22 RUS87716.1 - 1.9e-12 46.8 0.0 3.1e-05 23.7 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.20 RUS87717.1 - 3.3e-07 30.4 0.1 5.3e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Hyccin PF09790.9 RUS87718.1 - 1.1e-58 198.9 0.0 1.2e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Hyccin Hyccin PF09790.9 RUS87719.1 - 0.07 12.2 0.1 0.095 11.8 0.1 1.2 1 0 0 1 1 1 0 Hyccin COPI_C PF06957.11 RUS87719.1 - 0.43 9.3 0.9 0.67 8.6 0.9 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SelP_N PF04592.14 RUS87719.1 - 0.82 9.0 7.0 1.3 8.3 7.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DNA_primase_S PF01896.19 RUS87721.1 - 9e-57 192.0 0.2 1.4e-56 191.4 0.2 1.3 1 0 0 1 1 1 1 DNA primase small subunit Hormone_recep PF00104.30 RUS87722.1 - 2.1e-21 76.5 0.0 4.6e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 RUS87722.1 - 3.1e-16 59.6 6.2 3.1e-16 59.6 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Cwf_Cwc_15 PF04889.12 RUS87722.1 - 1.6 8.4 18.9 0.023 14.5 11.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CM2 PF03021.14 RUS87723.1 - 5.3 6.9 16.4 7 6.5 0.9 3.3 1 1 2 3 3 3 0 Influenza C virus M2 protein LapA_dom PF06305.11 RUS87723.1 - 8.2 6.3 25.8 2.1 8.2 6.2 3.1 1 1 2 3 3 3 0 Lipopolysaccharide assembly protein A domain Lectin_C PF00059.21 RUS87724.1 - 5.1e-18 65.8 1.8 7.1e-18 65.3 1.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain Antistasin PF02822.14 RUS87724.1 - 0.026 15.1 10.4 0.026 15.1 10.4 2.2 2 0 0 2 2 2 0 Antistasin family Lectin_C PF00059.21 RUS87725.1 - 5.7e-14 52.8 0.0 1.1e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Lectin C-type domain Antistasin PF02822.14 RUS87725.1 - 0.92 10.2 15.0 0.19 12.4 11.0 2.1 2 0 0 2 2 2 0 Antistasin family Lectin_C PF00059.21 RUS87726.1 - 2.5e-11 44.3 0.1 3.9e-11 43.6 0.1 1.3 1 1 0 1 1 1 1 Lectin C-type domain MMTV_SAg PF01054.17 RUS87726.1 - 0.027 14.0 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Sugar_tr PF00083.24 RUS87727.1 - 4.5e-122 408.1 15.5 5.7e-122 407.8 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS87727.1 - 2.7e-16 59.4 23.4 2.7e-16 59.4 23.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 RUS87729.1 - 1.2e-79 268.0 0.0 1.5e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RUS87729.1 - 1.9e-05 23.9 0.0 2.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Asp PF00026.23 RUS87731.1 - 8.4e-43 147.0 0.1 1.2e-42 146.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 RUS87731.1 - 3.2e-16 59.5 0.0 4.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 RUS87731.1 - 2.6e-10 40.8 0.0 7.7e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Il13Ra_Ig PF18001.1 RUS87732.1 - 0.043 13.9 0.4 0.13 12.3 0.4 1.8 1 1 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain Lectin_C PF00059.21 RUS87733.1 - 1.9e-10 41.5 0.1 3.8e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain MFS_1 PF07690.16 RUS87736.1 - 2.5e-37 128.6 62.0 1.3e-32 113.1 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 RUS87736.1 - 0.00084 17.8 18.0 0.0034 15.8 3.0 2.9 1 1 2 3 3 3 3 Transmembrane secretion effector WD40 PF00400.32 RUS87738.1 - 0.00018 22.2 0.1 6.8 7.7 0.0 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Tim54 PF11711.8 RUS87738.1 - 0.032 13.0 0.4 0.044 12.6 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4602 PF15375.6 RUS87738.1 - 2.9 8.2 11.7 5.4 7.3 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) CDC45 PF02724.14 RUS87738.1 - 6.1 5.0 8.7 7.4 4.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_2 PF12756.7 RUS87739.1 - 1.9e-05 24.9 9.2 0.0029 17.9 0.3 3.5 2 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) YABBY PF04690.13 RUS87739.1 - 0.083 13.4 4.0 0.15 12.7 4.0 1.4 1 0 0 1 1 1 0 YABBY protein zf-LYAR PF08790.11 RUS87739.1 - 0.1 12.5 3.5 2.4 8.1 2.3 2.9 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 RUS87739.1 - 0.13 13.2 17.1 0.26 12.2 0.1 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS87739.1 - 0.13 12.8 13.5 1.7 9.3 0.1 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type Cwf_Cwc_15 PF04889.12 RUS87739.1 - 0.16 11.6 19.5 0.24 11.1 19.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BolA PF01722.18 RUS87739.1 - 0.24 11.7 2.1 0.54 10.6 0.0 2.5 3 0 0 3 3 3 0 BolA-like protein zf-Di19 PF05605.12 RUS87739.1 - 0.37 11.1 8.5 8 6.9 4.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.18 RUS87739.1 - 0.78 9.8 8.1 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 XPA protein N-terminal Insulin PF00049.18 RUS87739.1 - 3.3 8.8 7.1 2 9.5 4.4 2.1 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family Rdx PF10262.9 RUS87739.1 - 4.8 7.4 6.0 2.8 8.2 0.6 2.8 2 1 1 3 3 3 0 Rdx family Cytochrom_c3_2 PF14537.6 RUS87739.1 - 9.7 6.7 17.7 0.38 11.2 7.2 3.0 1 1 1 2 2 1 0 Cytochrome c3 AT_hook PF02178.19 RUS87740.1 - 0.0003 20.3 6.1 4.3 7.5 0.1 3.5 3 0 0 3 3 3 3 AT hook motif Mononeg_mRNAcap PF14318.6 RUS87740.1 - 0.021 14.1 3.5 1.6 7.9 0.5 2.1 1 1 1 2 2 2 0 Mononegavirales mRNA-capping region V JHY PF15261.6 RUS87740.1 - 0.36 11.5 16.5 1.4 9.6 5.7 2.7 1 1 2 3 3 3 0 Jhy protein AT_hook PF02178.19 RUS87741.1 - 0.00055 19.5 12.6 0.013 15.2 4.4 3.0 2 0 0 2 2 2 2 AT hook motif RBR PF17208.3 RUS87741.1 - 2 9.2 12.5 0.22 12.3 7.6 1.9 2 0 0 2 2 2 0 RNA binding Region Glycos_transf_2 PF00535.26 RUS87742.1 - 8e-18 64.8 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS87742.1 - 5.4e-11 42.8 1.0 4.5e-07 30.2 0.0 3.0 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 RUS87742.1 - 0.0009 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Amnionless PF14828.6 RUS87743.1 - 0.017 14.0 0.0 0.017 14.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 RUS87743.1 - 0.031 14.2 0.1 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 TMEM154 protein family DUF4577 PF15145.6 RUS87743.1 - 0.038 14.0 0.3 0.051 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) MAM PF00629.23 RUS87744.1 - 1.1e-54 184.7 0.8 1.1e-32 113.2 0.1 2.5 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu EGF PF00008.27 RUS87744.1 - 0.18 12.1 7.2 0.56 10.6 7.2 1.8 1 0 0 1 1 1 0 EGF-like domain gp32 PF08804.10 RUS87744.1 - 0.18 11.8 1.1 0.33 11.0 1.1 1.3 1 0 0 1 1 1 0 gp32 DNA binding protein like MAM PF00629.23 RUS87745.1 - 8.6e-30 103.8 2.3 6.3e-24 84.7 0.0 2.9 3 0 0 3 3 3 2 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 RUS87745.1 - 4.5e-17 62.0 46.4 7e-10 39.0 15.8 3.5 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A zf-TAZ PF02135.16 RUS87745.1 - 5.9 7.4 15.2 4.2 7.9 4.8 2.3 2 0 0 2 2 2 0 TAZ zinc finger MAM PF00629.23 RUS87746.1 - 1.4e-20 73.8 0.0 1.1e-18 67.7 0.0 2.0 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 RUS87747.1 - 1.2e-32 113.1 7.7 1.1e-20 74.2 0.1 3.0 3 0 0 3 3 3 3 MAM domain, meprin/A5/mu Lectin_C PF00059.21 RUS87748.1 - 0.1 13.3 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 Lectin C-type domain Claudin_2 PF13903.6 RUS87750.1 - 2.8e-18 66.4 11.1 5.2e-18 65.5 11.1 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS87750.1 - 0.00068 19.6 12.8 0.0062 16.5 12.8 2.0 1 1 0 1 1 1 1 Tight junction protein, Claudin-like L_HMGIC_fpl PF10242.9 RUS87750.1 - 0.021 15.0 10.1 0.041 14.1 10.0 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PGG PF13962.6 RUS87750.1 - 0.48 10.3 4.2 7.3 6.4 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function Na_H_antiport_1 PF06965.12 RUS87750.1 - 0.72 8.6 4.6 0.2 10.4 1.5 1.5 2 0 0 2 2 2 0 Na+/H+ antiporter 1 TatC PF00902.18 RUS87750.1 - 1.8 8.3 10.8 10 5.9 11.0 1.9 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1634 PF07843.11 RUS87750.1 - 3.9 7.6 7.2 1.1 9.3 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Claudin_2 PF13903.6 RUS87751.1 - 3.7e-16 59.5 12.9 5.2e-16 59.0 12.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS87751.1 - 0.0013 18.7 14.7 0.0039 17.1 14.7 1.6 1 1 0 1 1 1 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 RUS87751.1 - 0.043 13.7 12.0 0.16 11.8 1.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 RUS87751.1 - 0.31 11.2 10.4 2.1 8.5 9.8 1.9 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 RUS87751.1 - 0.36 10.3 10.1 3.1 7.2 10.1 2.1 1 1 0 1 1 1 0 Clc-like BBE PF08031.12 RUS87754.1 - 0.0013 18.7 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 RUS87755.1 - 3.8e-16 59.1 0.2 5e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain V-SNARE_C PF12352.8 RUS87756.1 - 1e-18 67.3 1.7 1e-18 67.3 1.7 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RUS87756.1 - 3.5e-05 23.6 0.7 9.4e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 RUS87756.1 - 0.0028 18.0 1.7 0.0093 16.3 1.1 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus HSCB_C PF07743.13 RUS87756.1 - 0.057 13.9 0.4 0.33 11.5 0.0 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF5586 PF17824.1 RUS87757.1 - 9.4e-20 71.1 9.6 1.8e-19 70.2 9.4 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5586) Slu7 PF11708.8 RUS87757.1 - 0.013 15.2 4.3 0.028 14.2 4.3 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF5582 PF17819.1 RUS87757.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5582) PH PF00169.29 RUS87758.1 - 6.2e-36 123.1 0.7 3.6e-17 62.8 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RUS87758.1 - 3.5e-16 59.5 2.4 2.2e-08 34.5 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PDZ_6 PF17820.1 RUS87758.1 - 1.7e-14 53.4 0.2 3.5e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS87758.1 - 1.1e-10 41.8 0.3 1.7e-10 41.1 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 RUS87758.1 - 2e-07 31.4 3.8 0.021 15.2 0.1 3.8 3 2 0 3 3 3 2 Pleckstrin homology domain PDZ_2 PF13180.6 RUS87758.1 - 4.1e-05 23.8 0.3 7.5e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 RUS87758.1 - 0.0021 18.3 7.5 0.38 11.1 0.5 3.9 2 2 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 RUS87758.1 - 0.0042 17.2 0.3 7 6.8 0.0 3.4 3 1 0 3 3 3 1 PH domain PH_13 PF16652.5 RUS87758.1 - 0.013 15.3 0.1 5.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain GRASP55_65 PF04495.14 RUS87758.1 - 0.032 14.5 0.0 0.074 13.4 0.0 1.5 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF3426 PF11906.8 RUS87758.1 - 0.048 13.8 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) PH_15 PF17339.2 RUS87758.1 - 0.064 13.2 0.3 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 PH domain gpW PF02831.15 RUS87758.1 - 0.14 12.0 0.1 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 gpW Guanylate_cyc PF00211.20 RUS87759.1 - 2.1e-62 210.0 0.1 2.6e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain 7tm_1 PF00001.21 RUS87761.1 - 7.3e-34 117.3 0.1 8.6e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS87761.1 - 1e-05 25.1 2.4 1e-05 25.1 2.4 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS87761.1 - 0.0021 17.4 2.1 0.0024 17.2 0.1 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 RUS87761.1 - 0.0043 16.8 4.9 0.0077 16.0 2.0 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF420 PF04238.12 RUS87761.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF420) YbgT_YccB PF08173.11 RUS87761.1 - 3 8.0 6.0 0.3 11.2 0.5 2.2 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Lectin_C PF00059.21 RUS87762.1 - 1.2e-10 42.0 0.6 3.5e-10 40.6 0.6 1.8 1 0 0 1 1 1 1 Lectin C-type domain Ig_3 PF13927.6 RUS87763.1 - 7.5e-32 109.8 11.9 1.5e-12 48.0 0.2 5.4 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 RUS87763.1 - 6.7e-22 77.4 4.1 9.6e-09 35.2 0.2 5.3 5 0 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 RUS87763.1 - 2.3e-16 59.7 11.0 0.00014 21.9 0.6 5.5 4 1 1 5 5 5 4 Immunoglobulin domain Bravo_FIGEY PF13882.6 RUS87763.1 - 9.9e-14 52.5 7.4 2.2e-13 51.4 7.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_2 PF13895.6 RUS87763.1 - 3.2e-12 46.6 11.8 2.6e-06 27.7 0.2 5.2 5 0 0 5 5 5 2 Immunoglobulin domain Syndecan PF01034.20 RUS87763.1 - 1e-05 25.3 0.3 2.6e-05 24.0 0.3 1.6 1 0 0 1 1 1 1 Syndecan domain V-set PF07686.17 RUS87763.1 - 0.00019 21.6 5.2 1 9.6 0.4 5.3 4 1 0 4 4 4 1 Immunoglobulin V-set domain DUF3827 PF12877.7 RUS87763.1 - 0.0025 16.3 0.1 0.0037 15.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Protocadherin PF08374.11 RUS87763.1 - 0.0046 17.0 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Protocadherin Adeno_E3_CR1 PF02440.15 RUS87763.1 - 0.0061 16.3 1.7 0.026 14.3 0.1 2.9 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 TMEM154 PF15102.6 RUS87763.1 - 0.018 14.9 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 RUS87763.1 - 0.037 14.9 0.0 0.099 13.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 RUS87763.1 - 0.052 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein SIT PF15330.6 RUS87763.1 - 0.099 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Orf78 PF06024.12 RUS87763.1 - 0.11 12.9 0.4 0.24 11.7 0.4 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Insulin_TMD PF17870.1 RUS87763.1 - 0.16 12.0 5.4 0.5 10.5 5.4 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5385 PF17359.2 RUS87763.1 - 0.17 11.4 0.2 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF5640 PF18692.1 RUS87763.1 - 0.26 11.4 3.0 13 5.9 0.1 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5640) IQ PF00612.27 RUS87764.1 - 2.3e-26 89.1 21.6 3.5e-06 26.3 0.3 5.6 5 0 0 5 5 5 5 IQ calmodulin-binding motif DCX PF03607.17 RUS87764.1 - 4.9e-20 71.4 0.0 5e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 Doublecortin DCX PF03607.17 RUS87766.1 - 3.6e-11 43.0 0.0 6.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Doublecortin DUF3467 PF11950.8 RUS87766.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) UPF0193 PF05250.11 RUS87767.1 - 5.1e-35 121.3 3.5 6.1e-35 121.0 3.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF3585 PF12130.8 RUS87768.1 - 5.5e-38 130.2 21.4 1.9e-37 128.4 21.4 2.0 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 RUS87768.1 - 1.4e-23 83.1 0.3 1.4e-22 79.9 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS87768.1 - 1.7e-09 37.3 0.0 4.1e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain SVIP PF15811.5 RUS87768.1 - 0.1 13.0 2.6 0.7 10.4 2.6 2.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein DUF667 PF05018.13 RUS87769.1 - 3.3e-34 118.2 0.0 5e-23 81.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF667) WD40 PF00400.32 RUS87769.1 - 3.4e-28 97.3 23.7 0.00026 21.7 0.0 11.3 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS87769.1 - 1.1e-10 41.6 0.0 0.05 13.9 0.0 6.9 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 RUS87769.1 - 1.2e-05 25.0 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 HELP motif Nup160 PF11715.8 RUS87769.1 - 0.00017 20.4 0.1 0.008 14.9 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RUS87769.1 - 0.00089 18.1 0.1 0.0063 15.3 0.1 2.4 1 1 0 1 1 1 1 Nup133 N terminal like PD40 PF07676.12 RUS87769.1 - 0.14 12.1 0.4 55 3.9 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DSPc PF00782.20 RUS87770.1 - 4.3e-13 49.2 0.1 7.3e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS87770.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase S36_mt PF10937.8 RUS87771.1 - 6.8e-06 27.7 7.4 7.8e-05 24.2 0.2 2.2 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial V-ATPase_H_C PF11698.8 RUS87772.1 - 2.6e-05 24.3 2.6 3.7e-05 23.8 1.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 RUS87772.1 - 0.0033 16.9 2.5 0.67 9.4 0.3 2.4 1 1 1 2 2 2 2 Armadillo-like HEAT PF02985.22 RUS87772.1 - 0.0043 17.2 0.1 0.063 13.6 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 RUS87772.1 - 0.0092 16.0 0.2 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 RUS87772.1 - 0.015 14.6 0.2 0.031 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) HEAT_2 PF13646.6 RUS87772.1 - 0.023 15.1 0.0 1.1 9.7 0.0 3.0 2 1 1 3 3 3 0 HEAT repeats Arm_3 PF16186.5 RUS87772.1 - 0.08 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Atypical Arm repeat RICTOR_N PF14664.6 RUS87772.1 - 0.19 10.7 9.4 0.21 10.5 0.2 3.0 1 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term AAA_15 PF13175.6 RUS87772.1 - 0.36 10.5 13.4 0.67 9.6 13.4 1.4 1 1 0 1 1 1 0 AAA ATPase domain KRAB PF01352.27 RUS87772.1 - 1.3 8.8 4.4 2.4 7.9 4.4 1.5 1 0 0 1 1 1 0 KRAB box Fes1 PF08609.10 RUS87772.1 - 4.1 8.3 8.9 7 7.6 6.4 2.9 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 AAA_23 PF13476.6 RUS87772.1 - 4.2 7.8 15.1 0.99 9.9 10.8 2.0 2 0 0 2 2 2 0 AAA domain RXLR PF16810.5 RUS87772.1 - 6.2 7.3 8.0 1.1e+02 3.3 8.0 2.7 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity TMPIT PF07851.13 RUS87772.1 - 6.5 5.9 8.0 1.9 7.7 2.7 2.3 2 0 0 2 2 2 0 TMPIT-like protein WD40 PF00400.32 RUS87773.1 - 2.1e-10 41.0 13.7 0.1 13.5 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box PF00646.33 RUS87773.1 - 7.4e-09 35.3 1.0 1.9e-08 33.9 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS87773.1 - 1.6e-08 34.3 1.0 4.3e-08 32.9 1.0 1.8 1 0 0 1 1 1 1 F-box-like Proteasome PF00227.26 RUS87774.1 - 8.8e-44 149.3 0.0 9.9e-44 149.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HRM PF02793.22 RUS87775.1 - 3.6e-10 40.0 3.3 7.3e-10 39.0 3.3 1.5 1 0 0 1 1 1 1 Hormone receptor domain 7tm_2 PF00002.24 RUS87775.1 - 0.058 12.7 4.4 0.082 12.2 4.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 RUS87776.1 - 2e-37 128.8 16.9 2.7e-37 128.4 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Homeodomain PF00046.29 RUS87778.1 - 3.2e-21 74.9 1.1 7.1e-21 73.8 1.1 1.6 1 0 0 1 1 1 1 Homeodomain CSRNP_N PF16019.5 RUS87778.1 - 0.22 11.4 10.4 0.82 9.6 6.1 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus EPL1 PF10513.9 RUS87778.1 - 1 9.7 10.8 0.14 12.6 5.7 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like RR_TM4-6 PF06459.12 RUS87778.1 - 1.3 8.7 11.6 0.11 12.3 3.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 G0-G1_switch_2 PF15103.6 RUS87778.1 - 1.4 9.4 7.5 15 6.1 5.0 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 FAM199X PF15814.5 RUS87778.1 - 1.9 7.4 7.8 3.3 6.7 7.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF3306 PF11748.8 RUS87778.1 - 2.1 9.3 14.3 0.78 10.6 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Afi1 PF07792.12 RUS87778.1 - 2.1 8.9 12.3 2 8.9 4.9 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Suf PF05843.14 RUS87778.1 - 2.2 8.2 15.4 0.071 13.1 9.2 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Connexin PF00029.19 RUS87778.1 - 3.3 7.4 8.3 0.23 11.2 2.3 1.9 2 0 0 2 2 2 0 Connexin DUF4050 PF13259.6 RUS87778.1 - 3.5 7.9 14.4 7.1 6.9 7.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Neur_chan_memb PF02932.16 RUS87778.1 - 3.6 7.6 10.9 0.45 10.5 5.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DNApol_Exo PF18136.1 RUS87778.1 - 3.7 6.6 13.8 4.5 6.3 6.3 2.2 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain GREB1 PF15782.5 RUS87778.1 - 3.9 4.5 13.7 5.6 3.9 13.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 RUS87778.1 - 3.9 6.1 15.0 0.15 10.8 7.3 1.9 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 RUS87778.1 - 4.7 7.2 10.5 1.1 9.2 4.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Pex14_N PF04695.13 RUS87778.1 - 6.1 7.5 23.9 0.16 12.7 15.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4746 PF15928.5 RUS87778.1 - 6.1 6.2 8.8 3.5 7.0 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 RUS87778.1 - 6.4 6.9 10.1 1.1 9.4 4.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.12 RUS87778.1 - 6.9 5.5 14.5 0.05 12.6 4.9 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.6 RUS87778.1 - 8.3 6.1 10.0 12 5.5 3.8 2.2 2 0 0 2 2 2 0 FAM176 family PAT1 PF09770.9 RUS87778.1 - 9.6 4.3 21.6 0.32 9.2 15.8 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Arm PF00514.23 RUS87780.1 - 1e-35 120.6 31.9 7.3e-06 25.8 0.1 11.5 11 0 0 11 11 11 7 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 RUS87780.1 - 5.7e-20 71.7 0.4 7.5e-10 39.3 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS87780.1 - 3e-14 52.9 1.3 1.9e-06 28.0 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS87780.1 - 9e-13 48.5 3.2 0.00023 21.7 0.2 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) HEAT_2 PF13646.6 RUS87780.1 - 2.9e-12 46.8 10.8 0.1 13.0 2.2 6.9 2 1 6 8 8 8 5 HEAT repeats Ank_3 PF13606.6 RUS87780.1 - 6.5e-12 44.5 10.8 0.0037 17.6 0.1 6.7 7 0 0 7 7 6 3 Ankyrin repeat Ank PF00023.30 RUS87780.1 - 1.2e-09 38.1 7.0 0.0014 19.0 0.3 5.3 4 0 0 4 4 4 2 Ankyrin repeat Atx10homo_assoc PF09759.9 RUS87780.1 - 7.1e-08 32.4 7.2 0.43 10.6 0.1 5.4 5 0 0 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RUS87780.1 - 3e-06 27.6 14.8 0.7 10.5 0.0 7.8 8 0 0 8 8 7 2 HEAT-like repeat Arm_2 PF04826.13 RUS87780.1 - 0.00015 21.3 12.7 0.85 9.0 0.5 5.4 1 1 4 5 5 5 2 Armadillo-like HEAT PF02985.22 RUS87780.1 - 0.053 13.8 18.3 0.28 11.5 0.0 8.1 10 0 0 10 10 9 0 HEAT repeat DUF3361 PF11841.8 RUS87780.1 - 0.056 13.4 13.9 7.5 6.5 0.1 6.1 3 1 2 6 6 6 0 Domain of unknown function (DUF3361) Fes1 PF08609.10 RUS87780.1 - 0.19 12.7 1.2 0.98 10.3 0.1 2.9 3 0 0 3 3 2 0 Nucleotide exchange factor Fes1 UNC45-central PF11701.8 RUS87780.1 - 0.5 10.3 6.1 4.1 7.4 0.3 3.8 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 RUS87780.1 - 2.6 8.2 11.7 15 5.7 0.1 6.0 4 2 4 8 8 8 0 V-ATPase subunit H HMG_box PF00505.19 RUS87781.1 - 5.8e-18 65.1 1.7 1.3e-17 64.0 1.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS87781.1 - 3.4e-14 53.2 0.7 7.2e-14 52.1 0.7 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 RUS87781.1 - 0.00059 19.7 1.7 0.0015 18.5 1.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 zf-met PF12874.7 RUS87781.1 - 0.0009 19.5 4.8 0.0018 18.6 4.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS87781.1 - 0.0032 17.7 3.6 0.0032 17.7 3.6 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 RUS87781.1 - 0.0089 15.8 1.9 0.021 14.6 1.9 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 RUS87781.1 - 0.01 16.2 0.8 0.01 16.2 0.8 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Lipid_DES PF08557.10 RUS87781.1 - 0.14 11.7 0.7 2.2 7.8 0.7 2.6 1 1 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Polysacc_synt_4 PF04669.13 RUS87782.1 - 8.7e-21 74.3 0.2 3.6e-19 69.1 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis Band_7 PF01145.25 RUS87783.1 - 8.2e-30 104.1 0.4 8.2e-30 104.1 0.4 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 RUS87783.1 - 1.7e-28 98.4 2.6 1.7e-28 98.4 2.6 2.5 3 0 0 3 3 3 1 C-terminal region of band_7 Band_7_1 PF13421.6 RUS87783.1 - 0.0061 16.3 1.0 0.063 13.0 0.1 2.2 2 0 0 2 2 2 1 SPFH domain-Band 7 family DUF3130 PF11328.8 RUS87786.1 - 0.017 15.4 0.4 0.054 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Aldo_ket_red PF00248.21 RUS87788.1 - 1.5e-44 152.4 0.2 2.7e-43 148.3 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRRFIP PF09738.9 RUS87789.1 - 2.4e-19 69.9 7.7 2.4e-19 69.9 7.7 6.6 4 3 2 6 6 6 2 LRRFIP family IL23 PF16649.5 RUS87789.1 - 1.5 8.9 15.0 7.1 6.6 1.1 4.1 1 1 3 4 4 4 0 Interleukin 23 subunit alpha HTH_56 PF18662.1 RUS87790.1 - 0.0085 16.2 0.1 1 9.4 0.0 2.6 2 0 0 2 2 2 2 Cch helix turn helix domain hSac2 PF12456.8 RUS87791.1 - 3.5e-20 71.8 0.1 6.3e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Inositol phosphatase Syja_N PF02383.18 RUS87791.1 - 5.8e-12 45.5 0.4 1e-11 44.8 0.4 1.4 1 0 0 1 1 1 1 SacI homology domain Carb_anhydrase PF00194.21 RUS87793.1 - 1e-84 284.1 0.3 5e-80 268.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 RUS87794.1 - 3.5e-65 219.9 2.8 4.8e-65 219.5 2.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS87794.1 - 0.16 11.3 22.5 0.77 9.1 1.8 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS87794.1 - 0.59 9.7 24.0 0.023 14.3 16.8 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx BUD22 PF09073.10 RUS87795.1 - 0.005 16.2 3.1 0.0072 15.7 3.1 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 RUS87795.1 - 0.023 14.1 2.8 0.027 13.9 2.8 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RUS87795.1 - 0.031 14.1 2.2 0.043 13.7 2.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 RUS87795.1 - 0.077 12.6 1.3 0.088 12.4 1.3 1.2 1 0 0 1 1 1 0 PPP4R2 GCIP PF13324.6 RUS87795.1 - 0.17 11.4 3.7 0.24 11.0 3.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 RUS87795.1 - 0.43 10.6 5.1 0.67 10.0 5.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RUS87795.1 - 0.45 8.5 14.6 0.58 8.2 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS87795.1 - 0.79 8.2 5.7 0.98 7.9 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 RUS87795.1 - 2.7 8.4 24.0 4.5 7.7 24.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RUS87795.1 - 4.2 5.5 9.3 5.5 5.1 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 RUS87795.1 - 4.7 6.4 20.1 7.1 5.9 20.1 1.2 1 0 0 1 1 1 0 NOA36 protein GP67 PF17634.2 RUS87795.1 - 5.1 7.6 27.4 18 5.8 27.4 1.8 1 1 0 1 1 1 0 Gene product 67 SAP PF02037.27 RUS87797.1 - 1.8e-14 53.1 0.9 1.8e-14 53.1 0.9 2.1 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 RUS87797.1 - 6.1e-07 29.2 21.5 0.0033 17.2 2.4 4.4 4 1 0 4 4 4 3 Tho1/MOS11 C-terminal domain Telomere_Sde2_2 PF13297.6 RUS87797.1 - 4.1e-05 23.1 2.8 0.00025 20.6 0.2 2.7 2 0 0 2 2 2 1 Telomere stability C-terminal PASTA PF03793.19 RUS87797.1 - 0.0071 16.2 0.0 0.03 14.2 0.0 2.2 1 0 0 1 1 1 1 PASTA domain CENP-B_dimeris PF09026.10 RUS87797.1 - 0.12 12.8 3.6 0.25 11.8 3.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4065 PF13274.6 RUS87797.1 - 0.14 13.1 0.1 0.52 11.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF465 PF04325.13 RUS87797.1 - 1.4 9.0 6.6 18 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF465) eIF3_subunit PF08597.10 RUS87797.1 - 5.3 6.9 18.1 0.13 12.2 9.8 2.1 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit BIR PF00653.21 RUS87798.1 - 1.9e-27 95.7 7.9 1.1e-09 38.8 0.0 4.2 4 0 0 4 4 3 3 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS87798.1 - 3e-11 43.0 17.1 3e-11 43.0 17.1 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS87798.1 - 0.0005 19.9 16.5 0.0005 19.9 16.5 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 ATG16 PF08614.11 RUS87798.1 - 0.018 15.2 12.5 0.018 15.2 12.5 2.7 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 RUS87798.1 - 0.18 12.4 26.5 0.085 13.5 10.0 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 RUS87798.1 - 0.26 11.4 25.3 0.013 15.6 19.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RUS87798.1 - 0.55 9.1 31.1 2 7.2 23.5 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 RUS87798.1 - 2.8 7.4 26.5 3 7.4 10.3 2.8 1 1 2 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 RUS87798.1 - 5.9 6.2 16.4 27 4.0 16.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ING PF12998.7 RUS87798.1 - 8.3 7.1 13.0 4.6 7.9 9.4 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding YscO-like PF16789.5 RUS87798.1 - 8.4 6.4 23.8 1.6e+03 -1.0 24.2 2.7 2 1 0 2 2 2 0 YscO-like protein Hom_end_hint PF05203.16 RUS87798.1 - 9.8 6.0 7.7 16 5.3 7.7 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint zinc_ribbon_16 PF17034.5 RUS87799.1 - 8.6e-19 68.0 12.8 2.5e-18 66.5 12.8 1.9 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 RUS87799.1 - 3.1e-05 23.5 9.8 3.1e-05 23.5 9.8 2.8 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type DUF2875 PF11394.8 RUS87799.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) WD40 PF00400.32 RUS87799.1 - 0.18 12.7 1.1 8.5 7.4 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Rep_fac-A_3 PF08661.11 RUS87800.1 - 3.5e-21 75.5 0.1 3.9e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SicP-binding PF09119.10 RUS87800.1 - 0.075 13.0 0.0 0.64 10.0 0.0 2.0 1 1 0 2 2 2 0 SicP binding Snf7 PF03357.21 RUS87801.1 - 4.3e-24 85.0 14.4 8e-24 84.2 14.4 1.4 1 0 0 1 1 1 1 Snf7 ESCRT-II PF05871.12 RUS87801.1 - 0.0045 17.2 2.9 0.17 12.2 0.3 3.2 2 1 0 2 2 2 1 ESCRT-II complex subunit SNARE PF05739.19 RUS87801.1 - 0.24 11.4 4.2 15 5.7 0.1 3.5 3 1 0 3 3 3 0 SNARE domain RHINO PF15319.6 RUS87802.1 - 0.16 12.0 1.1 0.27 11.2 1.1 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Peptidase_C1 PF00112.23 RUS87803.1 - 1.8e-57 194.9 3.7 2.6e-57 194.4 3.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RUS87803.1 - 8.3e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS87803.1 - 0.33 9.7 4.4 1.9 7.2 1.0 2.4 3 0 0 3 3 3 0 Peptidase C1-like family Ank_2 PF12796.7 RUS87804.1 - 6e-18 65.2 0.2 2.6e-12 47.2 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS87804.1 - 2.4e-15 56.6 0.0 5.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS87804.1 - 1.3e-13 50.9 0.3 1.3e-06 28.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS87804.1 - 4e-12 45.2 0.1 9.5e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS87804.1 - 1.6e-11 44.1 0.7 0.00024 21.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat PI3K_1B_p101 PF10486.9 RUS87804.1 - 1.3 6.7 10.3 1.7 6.4 10.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 RUS87804.1 - 2.4 6.6 3.8 3 6.3 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 RUS87804.1 - 2.7 6.0 8.0 3.7 5.5 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi GREB1 PF15782.5 RUS87804.1 - 3.4 4.7 14.0 4.1 4.4 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 RUS87804.1 - 5.9 6.5 5.7 1.9 8.1 2.7 1.7 2 0 0 2 2 2 0 FAM176 family DDHD PF02862.17 RUS87805.1 - 3.4e-47 161.5 0.1 6.1e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 DDHD domain Ank_4 PF13637.6 RUS87807.1 - 2e-05 25.1 0.4 0.0027 18.3 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS87807.1 - 6.4e-05 23.5 3.2 0.021 15.4 0.6 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS87807.1 - 0.061 13.9 1.2 2e+02 3.1 0.0 4.8 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 RUS87807.1 - 0.092 13.1 0.5 22 5.5 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Img2 PF05046.14 RUS87808.1 - 1.6e-21 76.4 0.2 2.9e-21 75.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Lipase PF00151.19 RUS87809.1 - 3.1e-98 329.2 0.0 3.8e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS87809.1 - 0.0016 19.1 0.5 0.0032 18.1 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLAT PF01477.23 RUS87809.1 - 0.028 15.0 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 PLAT/LH2 domain TSP_1 PF00090.19 RUS87810.1 - 3.9e-273 881.8 406.9 1.4e-13 50.9 11.8 24.9 25 0 0 25 25 25 24 Thrombospondin type 1 domain Hepsin-SRCR PF09272.10 RUS87810.1 - 2.3e-05 24.9 0.2 8.3e-05 23.1 0.0 1.9 1 1 0 2 2 2 1 Hepsin, SRCR domain Pkinase PF00069.25 RUS87811.1 - 1.8e-53 181.6 0.0 2.3e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87811.1 - 3.9e-30 105.0 0.0 5.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS87811.1 - 1.5e-05 24.5 0.0 4.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS87811.1 - 0.009 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RUS87811.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAN_1 PF00024.26 RUS87812.1 - 2.7e-08 33.6 1.5 4.5e-08 33.0 0.7 1.7 1 1 1 2 2 2 1 PAN domain bZIP_2 PF07716.15 RUS87813.1 - 7.5e-11 42.0 9.9 1.4e-10 41.1 9.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RUS87813.1 - 0.071 13.2 11.7 0.15 12.2 11.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor Synaptobrevin PF00957.21 RUS87814.1 - 7.8e-30 102.5 0.2 9.2e-30 102.3 0.2 1.1 1 0 0 1 1 1 1 Synaptobrevin SNARE PF05739.19 RUS87814.1 - 0.00095 19.1 5.8 0.00095 19.1 5.8 2.0 2 1 0 2 2 2 1 SNARE domain Prominin PF05478.11 RUS87814.1 - 0.0023 16.0 0.0 0.0028 15.7 0.0 1.1 1 0 0 1 1 1 1 Prominin GPDPase_memb PF10110.9 RUS87814.1 - 0.0038 16.1 0.1 0.0044 15.8 0.1 1.0 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Fusion_gly PF00523.18 RUS87814.1 - 0.0098 14.2 0.1 0.012 13.9 0.1 1.1 1 0 0 1 1 1 1 Fusion glycoprotein F0 Ferlin_C PF16165.5 RUS87814.1 - 0.012 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Ferlin C-terminus DUF3671 PF12420.8 RUS87814.1 - 0.042 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function Vac7 PF12751.7 RUS87814.1 - 0.051 13.0 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 MCU PF04678.13 RUS87814.1 - 0.068 13.3 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Env-gp36 PF09590.10 RUS87814.1 - 0.085 11.3 0.0 0.085 11.3 0.0 1.0 1 0 0 1 1 1 0 Lentivirus surface glycoprotein WD40 PF00400.32 RUS87815.1 - 1.4e-10 41.5 4.2 0.016 16.1 0.0 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS87815.1 - 0.00079 19.7 0.1 0.36 11.2 0.1 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 RUS87815.1 - 0.0027 17.1 0.4 2.1 7.6 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 RUS87815.1 - 0.016 14.2 0.1 9.8 5.0 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 RUS87815.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain RIO1 PF01163.22 RUS87816.1 - 2.9e-76 255.3 0.1 2.9e-76 255.3 0.1 2.5 3 0 0 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 RUS87816.1 - 0.0014 17.4 0.1 0.0014 17.4 0.1 2.4 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 RUS87816.1 - 0.0016 18.5 0.0 0.34 10.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tetraspanin PF00335.20 RUS87817.1 - 5.8e-36 124.3 0.9 6.6e-36 124.1 0.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_3 PF06653.11 RUS87817.1 - 0.01 15.8 0.7 0.018 15.0 0.7 1.4 1 0 0 1 1 1 0 Tight junction protein, Claudin-like SUR7 PF06687.12 RUS87817.1 - 0.016 14.8 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family Herpes_TAF50 PF03326.13 RUS87818.1 - 0.046 12.4 1.2 0.063 11.9 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) BUD22 PF09073.10 RUS87819.1 - 0.00049 19.6 40.2 0.0006 19.3 40.2 1.1 1 0 0 1 1 1 1 BUD22 Zip PF02535.22 RUS87819.1 - 0.00073 18.8 0.2 0.00073 18.8 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 RUS87819.1 - 0.0097 14.7 2.8 0.011 14.5 2.8 1.1 1 0 0 1 1 1 1 Presenilin NPR3 PF03666.13 RUS87819.1 - 0.025 13.4 21.1 0.032 13.0 21.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CNDH2_C PF16858.5 RUS87819.1 - 0.028 14.3 21.7 0.04 13.8 21.7 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term ORC5_C PF14630.6 RUS87819.1 - 0.03 13.8 2.0 0.036 13.6 2.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus FAM60A PF15396.6 RUS87819.1 - 0.038 14.0 14.0 0.052 13.6 14.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.17 RUS87819.1 - 0.042 14.0 2.4 0.061 13.5 2.4 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3c_N PF05470.12 RUS87819.1 - 0.045 12.1 13.5 0.057 11.7 13.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RPOL_N PF14700.6 RUS87819.1 - 0.098 12.0 7.3 0.13 11.6 7.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal OATP PF03137.20 RUS87819.1 - 0.11 10.8 1.5 0.12 10.7 1.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIIAH PF12685.7 RUS87819.1 - 0.18 11.6 13.8 0.24 11.2 13.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Gti1_Pac2 PF09729.9 RUS87819.1 - 0.41 10.7 8.9 0.57 10.3 8.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family FGF-BP1 PF06473.12 RUS87819.1 - 0.77 9.5 12.1 1.1 9.0 12.1 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Nop14 PF04147.12 RUS87819.1 - 0.77 7.9 38.8 1.1 7.4 38.8 1.2 1 0 0 1 1 1 0 Nop14-like family RIC3 PF15361.6 RUS87819.1 - 1.3 9.4 11.0 1.7 9.1 11.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF913 PF06025.12 RUS87819.1 - 1.7 7.6 10.4 2.1 7.2 10.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 RUS87819.1 - 2.5 7.8 11.7 3.7 7.2 11.7 1.3 1 0 0 1 1 1 0 Connexin Tetraspanin PF00335.20 RUS87820.1 - 9.5e-32 110.5 5.4 1.5e-31 109.9 5.4 1.3 1 1 0 1 1 1 1 Tetraspanin family MDFI PF15316.6 RUS87820.1 - 0.014 15.5 0.9 0.046 13.8 0.0 2.2 2 0 0 2 2 2 0 MyoD family inhibitor MFS_1 PF07690.16 RUS87821.1 - 3.3e-14 52.6 23.2 3.3e-14 52.6 23.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 RUS87821.1 - 1.6 8.9 3.6 1.1 9.4 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function RNase_H PF00075.24 RUS87822.1 - 8.4e-16 58.4 0.0 2.4e-14 53.7 0.0 2.6 1 1 0 1 1 1 1 RNase H SNF PF00209.18 RUS87822.1 - 3e-07 29.5 0.0 4.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RXT2_N PF08595.11 RUS87822.1 - 0.01 15.9 11.5 0.019 15.0 11.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Secretin_N_2 PF07655.13 RUS87822.1 - 1.8 9.1 11.7 2.5 8.7 10.3 2.0 3 0 0 3 3 3 0 Secretin N-terminal domain DUF3818 PF12825.7 RUS87822.1 - 2.7 6.9 4.8 6.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) PBP1_TM PF14812.6 RUS87822.1 - 4.9 7.6 8.8 0.86 10.0 4.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 RUS87822.1 - 7.5 5.8 11.1 12 5.1 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein fn3 PF00041.21 RUS87823.1 - 0.0001 22.6 3.7 0.3 11.5 0.0 4.0 4 1 0 4 4 4 2 Fibronectin type III domain IL6Ra-bind PF09240.10 RUS87823.1 - 0.00049 20.5 2.6 0.0021 18.5 1.5 2.5 3 0 0 3 3 3 1 Interleukin-6 receptor alpha chain, binding ig PF00047.25 RUS87823.1 - 0.0046 17.1 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain EpoR_lig-bind PF09067.10 RUS87823.1 - 0.0052 17.0 0.2 0.015 15.5 0.2 1.8 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Izumo-Ig PF16706.5 RUS87823.1 - 0.0078 16.3 0.0 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 RUS87823.1 - 0.016 15.8 0.0 0.39 11.3 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS87823.1 - 0.016 15.7 0.1 0.086 13.4 0.0 2.3 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 RUS87824.1 - 6.5e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Comm PF15957.5 RUS87824.1 - 0.027 14.8 0.2 0.068 13.5 0.2 1.7 1 1 0 1 1 1 0 Commissureless Cadherin_C_2 PF16492.5 RUS87824.1 - 0.067 14.0 0.0 0.23 12.2 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Claudin_2 PF13903.6 RUS87824.1 - 0.096 12.4 0.5 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3828 PF12883.7 RUS87824.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) zf-C2H2 PF00096.26 RUS87825.1 - 4.3e-17 61.5 50.3 0.005 17.2 0.4 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS87825.1 - 3.6e-15 55.4 47.7 0.073 13.9 0.8 8.6 7 1 1 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS87825.1 - 9.8e-15 54.2 56.4 1.3e-05 25.4 0.4 9.6 9 2 0 9 9 9 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS87825.1 - 8.5e-10 38.2 8.9 4.4e-05 23.1 0.4 8.4 9 1 1 10 10 9 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RUS87825.1 - 1.6e-06 28.3 34.4 0.0097 16.2 0.3 6.2 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 RUS87825.1 - 8e-05 22.3 8.2 0.0042 16.8 2.6 5.1 5 1 0 5 5 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS87825.1 - 0.00058 20.1 0.8 0.00058 20.1 0.8 7.1 7 0 0 7 7 7 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS87825.1 - 0.00096 19.4 6.7 0.00096 19.4 6.7 5.1 3 1 3 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 RUS87825.1 - 0.0015 18.1 13.5 3.8 7.2 0.1 5.6 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS87825.1 - 0.0023 18.3 0.6 0.0023 18.3 0.6 8.0 9 1 1 10 10 8 1 Zinc-finger of C2H2 type Actin_micro PF17003.5 RUS87825.1 - 0.014 14.6 22.1 0.019 14.2 5.4 4.5 2 2 2 4 4 4 0 Putative actin-like family zf-LYAR PF08790.11 RUS87825.1 - 0.031 14.2 6.7 8 6.5 0.0 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger HalOD2 PF18547.1 RUS87825.1 - 0.065 13.1 8.2 0.32 10.9 0.1 3.6 4 0 0 4 4 4 0 Halobacterial output domain 2 HemY_N PF07219.13 RUS87825.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus zinc_ribbon_5 PF13719.6 RUS87825.1 - 0.24 11.2 21.0 3.1 7.6 0.3 5.6 6 0 0 6 6 6 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 RUS87825.1 - 2.8 8.7 22.9 3.9 8.3 1.0 4.6 2 1 3 5 5 5 0 zinc-ribbon family DUF2256 PF10013.9 RUS87825.1 - 3.6 7.8 10.2 12 6.2 0.0 4.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 RUS87825.1 - 5.4 7.6 10.2 3 8.4 0.6 3.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GFO_IDH_MocA PF01408.22 RUS87826.1 - 8.4e-21 75.0 0.1 1.3e-20 74.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 RUS87826.1 - 1.7e-12 47.4 0.2 4.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 RUS87826.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 RUS87826.1 - 0.025 15.0 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Fer4_20 PF14691.6 RUS87826.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.2 3 0 0 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Whib PF02467.16 RUS87826.1 - 0.33 11.6 0.2 0.33 11.6 0.2 3.5 4 0 0 4 4 4 0 Transcription factor WhiB TPMT PF05724.11 RUS87827.1 - 1.5e-40 139.2 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 RUS87827.1 - 2.9e-05 24.6 0.0 8.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS87827.1 - 0.00025 21.7 0.0 0.0032 18.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 RUS87827.1 - 0.0064 16.0 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_12 PF08242.12 RUS87827.1 - 0.075 13.8 0.0 0.21 12.4 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain ATP-synt_C PF00137.21 RUS87828.1 - 5e-23 81.2 33.6 2.1e-12 47.2 9.4 3.2 3 0 0 3 3 3 2 ATP synthase subunit C Apolipoprotein PF01442.18 RUS87829.1 - 0.00074 19.4 0.5 0.00074 19.4 0.5 2.8 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 RUS87829.1 - 0.058 13.5 0.5 0.26 11.4 0.3 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 RUS87829.1 - 0.15 11.3 3.4 0.19 11.0 0.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) CdvA PF18822.1 RUS87829.1 - 0.85 9.5 10.7 0.39 10.5 2.1 3.3 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Muted PF14942.6 RUS87829.1 - 2.4 8.5 10.6 2.4 8.5 0.2 3.9 4 0 0 4 4 4 0 Organelle biogenesis, Muted-like protein Vitellogenin_N PF01347.22 RUS87830.1 - 1.9e-79 267.7 0.0 4.8e-79 266.4 0.0 1.7 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1943 PF09172.11 RUS87830.1 - 1e-53 182.6 3.4 1.5e-51 175.5 0.5 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF1943) DUF1081 PF06448.11 RUS87830.1 - 8e-12 45.6 0.0 8e-12 45.6 0.0 5.9 5 1 0 5 5 5 1 Domain of Unknown Function (DUF1081) CreD PF06123.12 RUS87830.1 - 0.097 11.4 2.5 4 6.1 0.0 3.3 3 0 0 3 3 3 0 Inner membrane protein CreD DUF2781 PF10914.8 RUS87831.1 - 4.9e-13 49.7 12.3 1e-12 48.7 12.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) Fibrinogen_C PF00147.18 RUS87832.1 - 1.7e-52 178.4 6.0 4.6e-52 177.0 6.0 1.7 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF257 PF03192.13 RUS87832.1 - 0.0028 17.5 1.2 0.0065 16.3 1.2 1.6 1 1 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 SHE3 PF17078.5 RUS87832.1 - 0.052 13.3 6.8 0.21 11.3 1.0 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4056 PF13265.6 RUS87832.1 - 0.77 9.0 4.8 2 7.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4056) WSC PF01822.19 RUS87833.1 - 3e-06 27.3 4.2 0.051 13.8 0.1 2.8 2 2 0 2 2 2 2 WSC domain Toxin_TOLIP PF00087.21 RUS87834.1 - 0.3 11.4 12.9 0.51 10.6 12.9 1.4 1 0 0 1 1 1 0 Snake toxin and toxin-like protein SSF PF00474.17 RUS87835.1 - 1e-112 377.0 19.9 1.8e-112 376.2 19.9 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4079 PF13301.6 RUS87835.1 - 0.015 15.4 0.0 0.015 15.4 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4079) Ca_hom_mod PF14798.6 RUS87835.1 - 0.7 9.0 0.0 0.7 9.0 0.0 2.6 3 1 0 3 3 3 0 Calcium homeostasis modulator 7TM_GPCR_Srw PF10324.9 RUS87836.1 - 8.7e-33 114.0 27.6 1.2e-32 113.5 27.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS87836.1 - 2.8e-18 66.2 26.3 3.7e-18 65.8 26.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS87836.1 - 1.2e-05 24.9 23.8 0.00011 21.7 23.8 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4079 PF13301.6 RUS87836.1 - 0.0097 16.1 0.9 0.0097 16.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) zf-C4 PF00105.18 RUS87837.1 - 3e-28 98.1 11.5 3e-28 98.1 11.5 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS87837.1 - 1.2e-08 34.8 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Y_phosphatase PF00102.27 RUS87838.1 - 5.7e-55 186.4 0.1 7.8e-55 186.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS87838.1 - 1.7e-05 24.7 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS87838.1 - 0.029 14.5 0.7 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RUS87838.1 - 0.051 13.5 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family BRO1 PF03097.18 RUS87839.1 - 4.9e-114 381.1 2.7 4.9e-114 381.1 2.7 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RUS87839.1 - 3.9e-52 177.4 13.0 3.9e-52 177.4 13.0 3.3 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV Arm PF00514.23 RUS87840.1 - 6.4e-65 213.4 16.7 4.8e-06 26.4 0.0 13.7 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS87840.1 - 1.6e-17 63.6 11.7 4.8e-05 23.7 0.0 7.6 2 2 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 RUS87840.1 - 8e-09 35.8 5.9 0.012 16.1 0.2 7.7 9 0 0 9 9 9 1 HEAT-like repeat Adaptin_N PF01602.20 RUS87840.1 - 1.8e-08 33.4 2.0 0.0022 16.6 0.0 3.9 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.13 RUS87840.1 - 5.6e-08 32.6 4.4 0.034 13.6 0.1 6.1 3 2 4 7 7 7 3 Armadillo-like V-ATPase_H_C PF11698.8 RUS87840.1 - 2.1e-06 27.8 9.3 2.9 8.1 0.1 6.9 3 3 4 8 8 8 2 V-ATPase subunit H Cnd1 PF12717.7 RUS87840.1 - 3.8e-05 23.8 5.8 3.7 7.6 0.1 5.5 4 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RUS87840.1 - 0.00042 20.9 0.1 5.9 7.6 0.0 3.7 2 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RUS87840.1 - 0.00084 19.4 13.9 8.4 7.0 0.1 8.4 9 0 0 9 9 8 1 HEAT repeat UPF0147 PF03685.13 RUS87840.1 - 0.0057 16.7 0.4 4.9 7.3 0.1 3.8 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0147) MLTR_LBD PF17765.1 RUS87840.1 - 0.018 15.2 1.4 1.6 8.8 0.4 2.6 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain TM1506 PF08973.10 RUS87840.1 - 0.1 12.3 0.0 23 4.6 0.0 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF1893) Spo0A_C PF08769.11 RUS87840.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Tetraspanin PF00335.20 RUS87841.1 - 6e-57 193.0 10.2 6.8e-57 192.8 10.2 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 RUS87841.1 - 2.8 6.6 9.2 13 4.4 5.0 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2976 PF11190.8 RUS87841.1 - 4.4 7.2 7.4 1.4 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) Syntaxin_2 PF14523.6 RUS87842.1 - 1.4 9.3 5.0 2.8 8.4 2.3 2.7 2 0 0 2 2 2 0 Syntaxin-like protein Glyco_hydro_18 PF00704.28 RUS87843.1 - 1.1e-82 278.3 0.0 1.3e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5572 PF17733.1 RUS87843.1 - 0.072 12.9 0.1 8 6.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5572) 2OG-FeII_Oxy_3 PF13640.6 RUS87844.1 - 0.0028 18.5 0.0 0.0039 18.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrolase PF00702.26 RUS87845.1 - 1.4e-06 28.8 0.0 3.5e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lig_chan PF00060.26 RUS87846.1 - 1e-21 77.3 0.9 1.2e-21 77.1 0.9 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel DUF3367 PF11847.8 RUS87846.1 - 0.089 10.6 0.8 0.12 10.2 0.8 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Ubie_methyltran PF01209.18 RUS87847.1 - 0.013 14.9 0.4 0.013 14.9 0.4 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AceK PF06315.11 RUS87847.1 - 0.026 13.0 0.6 0.03 12.8 0.6 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Corona_nucleoca PF00937.18 RUS87847.1 - 0.062 12.3 0.1 0.076 12.0 0.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HEAT PF02985.22 RUS87848.1 - 1e-18 65.8 3.8 0.00019 21.4 0.2 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 RUS87848.1 - 6.2e-10 39.4 0.0 0.051 14.1 0.0 4.8 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 RUS87848.1 - 1.4e-07 31.8 0.0 0.021 15.2 0.0 3.7 2 1 0 2 2 2 1 HEAT repeats CLASP_N PF12348.8 RUS87848.1 - 2.6e-05 23.9 0.0 1.2 8.7 0.0 3.9 3 1 1 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 RUS87848.1 - 4.7e-05 23.9 0.0 0.047 14.3 0.0 3.8 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RUS87848.1 - 0.00019 21.5 0.0 0.38 10.8 0.0 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RUS87848.1 - 0.029 12.9 0.1 0.33 9.5 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region CAP PF00188.26 RUS87849.1 - 2.1e-16 60.9 1.8 4.5e-16 59.8 1.8 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aldose_epim PF01263.20 RUS87849.1 - 0.088 12.1 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 Aldose 1-epimerase CAP PF00188.26 RUS87850.1 - 4e-22 79.4 0.6 6.8e-22 78.6 0.6 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PMP22_Claudin PF00822.20 RUS87851.1 - 5.6e-08 32.8 10.5 7.7e-08 32.4 10.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 RUS87851.1 - 6.1e-05 22.9 12.2 8.6e-05 22.4 12.2 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Clc-like PF07062.12 RUS87851.1 - 0.11 12.0 13.8 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Clc-like Stevor PF17410.2 RUS87851.1 - 1.4 8.4 6.3 2.7 7.4 6.3 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame OST3_OST6 PF04756.13 RUS87851.1 - 1.4 8.2 7.6 3 7.1 7.6 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3340 PF11818.8 RUS87853.1 - 0.47 10.6 2.2 0.87 9.7 2.2 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Fibrinogen_C PF00147.18 RUS87854.1 - 3.2e-54 184.1 6.6 5.4e-54 183.3 6.6 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS87854.1 - 0.0073 16.2 4.5 0.016 15.1 3.9 1.8 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 RUS87854.1 - 0.0083 16.0 2.7 0.18 11.6 1.9 2.2 2 0 0 2 2 2 1 PIN like domain ABC_tran_CTD PF16326.5 RUS87854.1 - 0.013 15.8 2.6 0.41 10.9 0.5 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain EzrA PF06160.12 RUS87854.1 - 0.013 13.7 10.0 0.018 13.2 10.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 RUS87854.1 - 0.023 14.7 3.9 0.055 13.5 3.9 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 RUS87854.1 - 0.024 15.0 9.9 0.12 12.8 3.5 3.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CorA PF01544.18 RUS87854.1 - 0.053 12.8 4.1 0.087 12.1 4.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.12 RUS87854.1 - 0.11 13.0 12.0 0.15 12.5 0.9 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 RUS87854.1 - 0.23 11.4 6.9 0.54 10.2 1.7 3.1 1 1 1 3 3 3 0 Heat shock factor binding protein 1 Tropomyosin PF00261.20 RUS87854.1 - 0.23 10.8 11.9 1 8.7 11.9 2.0 1 1 0 1 1 1 0 Tropomyosin V_ATPase_I PF01496.19 RUS87854.1 - 0.24 9.3 10.4 0.36 8.7 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BST2 PF16716.5 RUS87854.1 - 0.24 12.0 8.5 0.096 13.3 4.4 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Baculo_PEP_C PF04513.12 RUS87854.1 - 0.32 11.1 16.4 2.3 8.3 9.1 3.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ORF6C PF10552.9 RUS87854.1 - 0.33 11.1 7.2 0.12 12.5 1.4 2.6 1 1 1 2 2 2 0 ORF6C domain DASH_Dad2 PF08654.10 RUS87854.1 - 0.58 10.6 5.0 8.6 6.8 0.7 2.9 1 1 2 3 3 3 0 DASH complex subunit Dad2 Laminin_II PF06009.12 RUS87854.1 - 0.68 9.9 16.0 0.26 11.3 2.8 3.3 2 1 1 3 3 3 0 Laminin Domain II Nup54 PF13874.6 RUS87854.1 - 0.88 9.7 5.9 19 5.4 4.9 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CK2S PF15011.6 RUS87854.1 - 1.1 9.1 7.4 7.7 6.4 1.2 3.1 1 1 2 3 3 3 0 Casein Kinase 2 substrate STAT_alpha PF01017.20 RUS87854.1 - 1.3 8.9 10.8 1.5 8.7 5.5 2.3 1 1 0 2 2 2 0 STAT protein, all-alpha domain DUF745 PF05335.13 RUS87854.1 - 1.6 8.4 8.5 0.33 10.7 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF724 PF05266.14 RUS87854.1 - 1.6 8.5 7.6 1.3 8.8 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DASH_Dam1 PF08653.10 RUS87854.1 - 1.6 8.5 4.4 35 4.3 0.1 3.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 SlyX PF04102.12 RUS87854.1 - 1.7 9.3 4.0 24 5.6 0.0 3.1 3 0 0 3 3 3 0 SlyX Fib_alpha PF08702.10 RUS87854.1 - 2 8.6 14.3 0.29 11.3 8.6 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2120 PF09893.9 RUS87854.1 - 2 8.5 7.3 1.2 9.2 2.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) CCDC-167 PF15188.6 RUS87854.1 - 3.1 8.2 7.1 9.9 6.6 6.1 2.3 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 YtxH PF12732.7 RUS87854.1 - 3.1 8.4 4.4 8 7.1 2.2 2.6 2 1 0 2 2 2 0 YtxH-like protein DUF4795 PF16043.5 RUS87854.1 - 3.9 7.0 15.2 9.5 5.8 14.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 RUS87854.1 - 3.9 7.5 13.2 0.77 9.8 3.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 RUS87854.1 - 4.4 7.6 9.5 1.9 8.7 1.1 3.1 3 0 0 3 3 3 0 Haemolysin XhlA Hemagglutinin PF00509.18 RUS87854.1 - 5 5.4 11.0 4.5 5.5 8.1 2.0 1 1 1 2 2 2 0 Haemagglutinin FlaC_arch PF05377.11 RUS87854.1 - 5.3 7.5 11.1 10 6.6 0.3 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Cyclin_N PF00134.23 RUS87855.1 - 5.8e-31 106.9 3.2 2.6e-30 104.8 0.3 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS87855.1 - 1e-22 80.5 1.8 2e-22 79.5 0.1 2.3 3 0 0 3 3 3 1 Cyclin, C-terminal domain CBF PF03914.17 RUS87856.1 - 2.2e-47 161.2 4.6 5.4e-47 160.0 0.0 3.2 3 0 0 3 3 3 1 CBF/Mak21 family Gal-bind_lectin PF00337.22 RUS87857.1 - 2.3e-14 53.0 0.1 4.9e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 Galactoside-binding lectin Gal-bind_lectin PF00337.22 RUS87858.1 - 5.8e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin Peptidase_M28 PF04389.17 RUS87859.1 - 1.3e-39 136.0 0.1 1.6e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M28 AceK PF06315.11 RUS87860.1 - 0.032 12.7 0.1 0.035 12.6 0.1 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) HSP90 PF00183.18 RUS87861.1 - 1e-233 776.9 32.4 1.3e-233 776.6 32.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RUS87861.1 - 4.7e-15 56.1 0.0 9.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RUS87861.1 - 1.1e-09 38.3 0.1 3e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 RUS87861.1 - 0.0045 17.1 11.8 0.0045 17.1 11.8 2.1 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Med26 PF08711.11 RUS87861.1 - 0.11 12.6 1.2 0.3 11.1 0.2 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain CDC45 PF02724.14 RUS87861.1 - 2.3 6.4 15.0 4.8 5.4 15.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.20 RUS87862.1 - 7.7e-23 80.4 0.1 2.7e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.6 RUS87862.1 - 6.2e-05 22.8 0.1 0.00016 21.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RUS87862.1 - 0.00033 20.9 0.0 0.0008 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RUS87862.1 - 0.0073 16.7 0.4 0.054 13.9 0.1 2.6 3 1 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RUS87862.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 RUS87862.1 - 0.019 15.1 0.1 0.046 13.9 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like DUF4523 PF15023.6 RUS87862.1 - 0.031 14.1 0.0 0.098 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Il2rg PF15874.5 RUS87863.1 - 2.8e-17 62.7 0.1 4.5e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Dimer_Tnp_hAT PF05699.14 RUS87864.1 - 2e-06 27.5 0.2 4.4e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 RUS87865.1 - 6e-17 61.9 0.0 9.2e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 RUS87865.1 - 1.2e-08 34.7 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Peptidase_A17 PF05380.13 RUS87866.1 - 1.3e-44 152.0 0.0 2.6e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF5641 PF18701.1 RUS87866.1 - 4.5e-23 81.2 0.1 1.1e-22 80.0 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) DUF1759 PF03564.15 RUS87866.1 - 7.9e-11 42.1 0.0 2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RVT_1 PF00078.27 RUS87866.1 - 0.0092 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS87866.1 - 0.12 12.6 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HLH PF00010.26 RUS87867.1 - 2.5e-17 62.6 0.1 2.5e-17 62.6 0.1 2.6 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain 7tm_2 PF00002.24 RUS87868.1 - 0.00014 21.3 9.0 0.00017 21.0 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TcpE PF12648.7 RUS87868.1 - 0.052 14.1 0.6 0.062 13.8 0.6 1.2 1 0 0 1 1 1 0 TcpE family 7tm_2 PF00002.24 RUS87869.1 - 0.0071 15.7 0.2 0.0089 15.3 0.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ras PF00071.22 RUS87870.1 - 1e-24 87.0 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS87870.1 - 1.1e-10 41.7 0.2 3.4e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS87870.1 - 0.00069 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PALP PF00291.25 RUS87871.1 - 6.4e-37 127.5 0.0 6.9e-27 94.6 0.0 2.7 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme PAN_1 PF00024.26 RUS87873.1 - 2.9e-20 72.0 21.9 2e-07 30.8 1.3 3.6 2 1 1 3 3 3 3 PAN domain PAN_4 PF14295.6 RUS87873.1 - 0.018 15.0 19.5 0.29 11.1 0.7 3.8 3 0 0 3 3 3 0 PAN domain FNIP PF05725.12 RUS87875.1 - 1.1e-06 28.7 6.0 0.64 10.2 0.0 5.0 5 0 0 5 5 5 2 FNIP Repeat DUF4128 PF13554.6 RUS87875.1 - 0.00018 21.5 0.7 0.83 9.7 0.0 3.0 1 1 2 3 3 3 2 Bacteriophage related domain of unknown function RCSD PF05177.12 RUS87875.1 - 0.0012 19.7 0.1 0.011 16.6 0.1 2.3 1 1 0 1 1 1 1 RCSD region LAS2 PF15792.5 RUS87875.1 - 0.038 14.5 2.5 1.4e+02 3.1 0.0 4.3 4 0 0 4 4 4 0 Lung adenoma susceptibility protein 2 PH PF00169.29 RUS87875.1 - 0.064 13.8 0.8 21 5.7 0.1 2.9 1 1 1 2 2 2 0 PH domain ChapFlgA_N PF17656.1 RUS87875.1 - 0.15 12.2 0.2 78 3.5 0.0 3.2 1 1 3 4 4 4 0 FlgA N-terminal domain DUF4689 PF15755.5 RUS87875.1 - 0.18 11.4 2.2 2.2 7.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4689) DUF824 PF05688.11 RUS87875.1 - 2.8 7.9 5.8 1.9e+02 2.0 0.2 3.9 4 0 0 4 4 4 0 Salmonella repeat of unknown function (DUF824) SNF PF00209.18 RUS87876.1 - 7.3e-175 582.6 32.8 2.5e-140 468.7 18.4 2.0 1 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Phage_holin_2_4 PF16082.5 RUS87876.1 - 0.2 11.4 1.2 0.49 10.2 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PGF-CTERM PF18204.1 RUS87876.1 - 1.2 9.2 3.7 2.1 8.4 0.2 2.7 2 0 0 2 2 2 0 PGF-CTERM motif TRAM_LAG1_CLN8 PF03798.16 RUS87878.1 - 6.3e-22 78.3 24.7 1.3e-21 77.3 23.4 1.8 2 0 0 2 2 2 1 TLC domain DUF2985 PF11204.8 RUS87878.1 - 0.025 14.7 1.1 0.025 14.7 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) PAPA-1 PF04795.12 RUS87879.1 - 3.7e-10 40.5 9.1 3.7e-10 40.5 9.1 2.4 2 1 0 2 2 2 1 PAPA-1-like conserved region zf-HIT PF04438.16 RUS87879.1 - 2.4e-05 24.1 5.2 3.6e-05 23.5 5.2 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF3247 PF11607.8 RUS87879.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF5560 PF17715.1 RUS87879.1 - 0.071 12.5 2.4 5.5 6.4 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5560) SprA-related PF12118.8 RUS87879.1 - 0.43 9.7 6.7 0.27 10.4 4.5 1.6 2 0 0 2 2 2 0 SprA-related family Poxvirus_B22R PF04395.12 RUS87879.1 - 7.8 6.0 12.4 2.6 7.5 1.3 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein Pkinase PF00069.25 RUS87881.1 - 1.2e-68 231.4 0.0 1.6e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87881.1 - 4.3e-34 118.0 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RUS87881.1 - 1.1e-07 32.4 2.7 2.8e-07 31.1 2.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RUS87881.1 - 0.00019 20.9 0.0 0.00038 19.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS87881.1 - 0.016 14.2 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RUS87881.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRICHOS PF04089.14 RUS87884.1 - 9.3 6.6 6.6 0.93 9.8 1.0 2.2 2 0 0 2 2 2 0 BRICHOS domain Ig_3 PF13927.6 RUS87885.1 - 2.6e-24 85.6 0.0 1.4e-11 44.9 0.0 5.6 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 RUS87885.1 - 5e-22 78.0 0.0 1.7e-08 34.7 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain I-set PF07679.16 RUS87885.1 - 6.5e-19 67.8 0.0 1.9e-10 40.6 0.0 5.5 5 1 0 5 5 5 2 Immunoglobulin I-set domain ig PF00047.25 RUS87885.1 - 9.5e-17 61.0 0.0 2e-06 27.9 0.0 5.9 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 RUS87885.1 - 8.8e-10 38.7 4.5 0.69 10.1 0.0 7.0 6 2 1 7 7 7 2 Immunoglobulin V-set domain fn3 PF00041.21 RUS87885.1 - 9.3e-10 38.7 0.1 1.7e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Izumo-Ig PF16706.5 RUS87885.1 - 0.00021 21.3 0.0 1.5 8.9 0.0 4.3 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 RUS87885.1 - 0.00067 19.7 0.0 0.0029 17.6 0.0 2.1 2 0 0 2 2 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RUS87885.1 - 0.0023 18.2 0.0 0.34 11.2 0.0 4.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS87885.1 - 0.0035 17.7 0.1 0.13 12.7 0.0 3.5 4 1 0 4 4 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS87885.1 - 0.027 14.0 0.0 42 3.8 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain C2-set PF05790.15 RUS87885.1 - 0.11 12.7 0.0 0.74 10.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain DUF3824 PF12868.7 RUS87885.1 - 5.3 7.7 8.3 0.4 11.3 3.2 1.7 2 0 0 2 2 1 0 Domain of unknwon function (DUF3824) FAS_meander PF17951.1 RUS87887.1 - 0.19 11.6 0.3 22 4.8 0.0 2.3 1 1 0 2 2 2 0 Fatty acid synthase meander beta sheet domain DNA_pol_phi PF04931.13 RUS87887.1 - 5.9 4.9 28.3 8.3 4.4 28.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi mRNA_cap_enzyme PF01331.19 RUS87888.1 - 1.7e-53 181.4 0.2 2.6e-53 180.8 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 RUS87888.1 - 9.6e-21 74.5 0.0 2.7e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 RUS87888.1 - 8.9e-09 35.3 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RUS87888.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 RUS87888.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 RUS87888.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DNA_ligase_A_M PF01068.21 RUS87888.1 - 0.045 13.4 0.0 0.32 10.6 0.0 1.9 1 1 1 2 2 2 0 ATP dependent DNA ligase domain Y_phosphatase3 PF13350.6 RUS87888.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Cmc1 PF08583.10 RUS87889.1 - 5.6e-13 48.7 4.2 9e-13 48.1 4.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 RUS87889.1 - 2.1 8.5 5.9 0.26 11.4 1.3 1.8 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ion_trans_2 PF07885.16 RUS87890.1 - 1.3e-36 124.4 17.4 3.4e-18 65.4 1.0 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS87890.1 - 2.1e-09 37.0 7.7 3.3e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Ion transport protein Sarcoglycan_1 PF04790.13 RUS87890.1 - 0.18 11.1 3.4 0.15 11.4 1.4 1.6 1 1 1 2 2 2 0 Sarcoglycan complex subunit protein TatD_DNase PF01026.21 RUS87891.1 - 4.1e-15 55.8 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase AhpC-TSA PF00578.21 RUS87892.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Abhydrolase_5 PF12695.7 RUS87895.1 - 2.6e-05 24.1 0.0 6.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family GA-like PF17573.2 RUS87895.1 - 0.013 15.4 0.0 0.044 13.7 0.0 2.0 1 0 0 1 1 1 0 GA-like domain GCIP PF13324.6 RUS87895.1 - 0.14 11.7 1.2 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Arf PF00025.21 RUS87896.1 - 4.8e-28 97.8 0.0 2e-23 82.7 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 RUS87896.1 - 6.8e-13 48.4 0.1 1.7e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 RUS87896.1 - 7.4e-06 25.7 0.2 0.00024 20.7 0.0 2.4 2 1 0 2 2 2 1 Ras family Roc PF08477.13 RUS87896.1 - 8.5e-06 26.0 0.2 0.033 14.4 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS87896.1 - 0.00019 21.4 2.5 0.086 12.7 0.1 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 RUS87896.1 - 0.0021 18.6 1.5 2.6 8.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 RUS87896.1 - 0.0025 17.4 0.5 2.3 7.8 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 RUS87896.1 - 0.0045 17.3 0.5 0.012 15.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 RUS87896.1 - 0.0052 16.7 1.1 0.25 11.2 0.0 2.5 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 RUS87896.1 - 0.0093 16.5 0.5 1.7 9.2 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RUS87896.1 - 0.019 15.4 4.7 0.13 12.6 4.4 2.8 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_L9_C PF03948.14 RUS87896.1 - 0.024 15.1 0.3 55 4.3 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L9, C-terminal domain AAA_33 PF13671.6 RUS87896.1 - 0.034 14.3 0.0 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RUS87896.1 - 0.046 13.5 0.2 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 RUS87896.1 - 0.064 12.9 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 RUS87896.1 - 0.13 11.6 0.1 0.78 9.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 RUS87896.1 - 0.14 11.9 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 RUS87896.1 - 0.36 10.1 4.0 12 5.2 4.0 2.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 RUS87897.1 - 2.9e-36 123.1 0.0 5.5e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS87897.1 - 8.6e-07 29.0 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 RUS87897.1 - 0.00011 21.8 0.0 0.036 13.6 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RUS87897.1 - 0.08 13.0 0.5 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 zf-C2H2 PF00096.26 RUS87899.1 - 1.7e-13 50.2 90.4 0.015 15.7 2.4 11.0 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS87899.1 - 9.7e-09 35.3 87.4 0.35 11.8 1.2 11.0 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RUS87899.1 - 0.0059 16.3 0.9 0.0059 16.3 0.9 6.8 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS87899.1 - 0.015 15.6 51.6 0.45 10.8 0.1 9.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS87899.1 - 0.3 11.5 0.0 0.3 11.5 0.0 8.6 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RUS87899.1 - 6.5 7.3 33.5 0.19 12.2 0.6 6.2 6 1 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger HPS3_Mid PF14762.6 RUS87900.1 - 4e-57 193.7 0.0 8.6e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 RUS87900.1 - 3.4e-43 147.6 1.5 5.2e-43 147.0 1.5 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 HPS3_C PF14763.6 RUS87900.1 - 1.6e-07 31.0 4.0 0.0026 17.2 0.1 3.3 3 0 0 3 3 3 3 Hermansky-Pudlak syndrome 3, C-terminal Amidohydro_1 PF01979.20 RUS87901.1 - 4.6e-11 42.6 0.0 5.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RUS87901.1 - 6.9e-08 32.4 0.0 8.4e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 RUS87902.1 - 0.00048 19.6 0.2 0.0016 17.8 0.2 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RUS87902.1 - 0.0016 18.0 0.1 0.0025 17.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.21 RUS87902.1 - 0.14 11.5 0.1 0.22 10.9 0.1 1.6 1 1 0 1 1 1 0 TatD related DNase RRM_1 PF00076.22 RUS87903.1 - 1.4e-36 124.1 0.1 8.1e-12 44.8 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RUS87903.1 - 3.8e-05 23.5 0.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RUS87903.1 - 0.071 13.2 0.0 48 4.2 0.0 3.8 3 0 0 3 3 3 0 RNA recognition motif DUF3824 PF12868.7 RUS87905.1 - 0.056 14.1 1.7 0.056 14.1 1.7 1.7 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF3311 PF11755.8 RUS87906.1 - 0.039 13.9 0.8 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) SPOC PF07744.13 RUS87907.1 - 1.1e-31 109.8 0.0 1.2e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 SPOC domain DUF2457 PF10446.9 RUS87908.1 - 0.02 14.0 20.1 0.027 13.6 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 RUS87908.1 - 0.032 14.3 10.2 0.053 13.5 10.1 1.5 1 1 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 RUS87908.1 - 0.39 10.0 22.1 0.53 9.6 22.1 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 RUS87908.1 - 0.45 8.7 13.3 0.56 8.4 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 RUS87908.1 - 0.59 8.1 3.7 0.63 8.1 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 RUS87908.1 - 0.7 9.2 10.9 0.78 9.0 10.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RUS87908.1 - 2.8 6.0 16.2 3.6 5.7 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS87908.1 - 3.9 6.8 13.8 4.7 6.5 13.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RUS87908.1 - 9.6 4.2 24.9 12 3.8 24.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DNA_pol_B PF00136.21 RUS87909.1 - 1.5e-128 429.4 0.3 2.1e-128 428.9 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 RUS87909.1 - 4.8e-47 160.1 2.1 9.6e-47 159.1 2.1 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 RUS87909.1 - 5.8e-42 144.0 0.1 1.6e-41 142.6 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 RUS87909.1 - 0.0032 16.4 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 RUS87909.1 - 0.096 11.2 0.4 0.21 10.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) DP PF08781.10 RUS87910.1 - 1e-63 213.3 5.6 2.6e-63 212.0 2.9 2.6 3 0 0 3 3 3 1 Transcription factor DP E2F_TDP PF02319.20 RUS87910.1 - 1.9e-25 88.7 0.0 4.7e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Tmemb_55A PF09788.9 RUS87911.1 - 2e-73 246.5 7.0 2.4e-73 246.3 7.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A zinc_ribbon_12 PF11331.8 RUS87911.1 - 0.028 14.2 9.1 0.74 9.7 1.0 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain DAG1 PF05454.11 RUS87911.1 - 0.046 13.1 1.4 0.088 12.2 1.4 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1451 PF07295.11 RUS87911.1 - 0.62 10.1 5.6 1.6 8.8 0.8 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain C1_1 PF00130.22 RUS87911.1 - 1.1 9.2 9.0 0.66 9.9 0.4 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.21 RUS87911.1 - 1.9 8.8 18.1 4.1 7.7 1.6 3.1 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain UPF1_Zn_bind PF09416.10 RUS87911.1 - 2.4 8.1 8.6 0.078 12.9 2.1 1.8 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Formyl_trans_N PF00551.19 RUS87912.1 - 6.6e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 RUS87912.1 - 7.8e-15 54.9 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ECM11 PF15463.6 RUS87912.1 - 0.034 14.7 0.1 0.051 14.2 0.1 1.2 1 0 0 1 1 1 0 Extracellular mutant protein 11 Ephrin_rec_like PF07699.13 RUS87913.1 - 3.7e-26 90.6 28.0 1.7e-12 46.9 4.0 4.9 3 1 1 4 4 4 3 Putative ephrin-receptor like Sushi PF00084.20 RUS87913.1 - 9.9e-23 80.5 33.6 1.8e-06 28.4 0.4 7.0 6 0 0 6 6 6 4 Sushi repeat (SCR repeat) Laminin_G_3 PF13385.6 RUS87913.1 - 2e-14 54.0 2.2 4e-14 53.0 2.2 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 RUS87913.1 - 2.5e-08 34.0 67.8 6.9e-05 23.1 7.4 7.4 7 0 0 7 7 7 4 EGF-like domain Pentaxin PF00354.17 RUS87913.1 - 1.4e-05 24.9 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family HYR PF02494.16 RUS87913.1 - 2.6e-05 24.5 0.1 0.00012 22.3 0.1 2.3 1 0 0 1 1 1 1 HYR domain EGF_CA PF07645.15 RUS87913.1 - 0.00018 21.7 1.6 0.00018 21.7 1.6 9.4 8 1 1 9 9 9 2 Calcium-binding EGF domain Vps51 PF08700.11 RUS87913.1 - 0.12 12.5 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Vps51/Vps67 DUF2318 PF10080.9 RUS87913.1 - 0.27 11.4 8.3 1.5 9.0 0.2 3.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) hEGF PF12661.7 RUS87913.1 - 1.8 9.3 62.9 0.24 12.1 5.5 8.4 7 0 0 7 7 7 0 Human growth factor-like EGF Ephrin_rec_like PF07699.13 RUS87914.1 - 3.6e-09 36.2 4.6 1e-08 34.8 4.6 1.8 1 0 0 1 1 1 1 Putative ephrin-receptor like EGF_3 PF12947.7 RUS87914.1 - 0.00083 19.5 10.4 0.0026 17.9 10.4 1.9 1 1 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.7 RUS87914.1 - 0.0019 18.2 4.4 0.0052 16.8 4.4 1.8 1 0 0 1 1 1 1 MSP1 EGF domain 1 cEGF PF12662.7 RUS87914.1 - 0.029 14.3 2.2 0.029 14.3 2.2 2.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 RUS87914.1 - 0.65 10.7 8.0 0.19 12.4 3.2 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF EF-hand_1 PF00036.32 RUS87917.1 - 2.2e-33 111.3 15.9 3.9e-06 26.0 0.1 6.9 6 1 1 7 7 7 6 EF hand EF-hand_6 PF13405.6 RUS87917.1 - 8.8e-29 97.0 17.4 6.1e-05 22.6 0.2 6.9 6 1 1 7 7 7 6 EF-hand domain EF-hand_7 PF13499.6 RUS87917.1 - 1.8e-26 92.4 16.9 5.8e-10 39.5 1.3 3.9 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RUS87917.1 - 9.1e-22 75.5 12.7 5.8e-05 22.4 0.1 6.6 6 1 1 7 7 7 5 EF hand EF-hand_8 PF13833.6 RUS87917.1 - 2.7e-15 55.9 11.7 0.0011 18.7 0.3 5.8 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_10 PF14788.6 RUS87917.1 - 2.8e-05 23.9 8.2 5.7 6.9 0.0 5.6 5 0 0 5 5 5 1 EF hand Dockerin_1 PF00404.18 RUS87917.1 - 0.00055 20.1 2.8 0.66 10.2 0.3 3.6 4 0 0 4 4 4 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RUS87917.1 - 0.0052 17.1 11.9 1.3 9.4 1.1 5.0 3 1 1 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region GPHH PF16905.5 RUS87917.1 - 0.0052 16.5 0.1 5.1 6.9 0.1 2.9 3 0 0 3 3 3 2 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 RUS87917.1 - 0.011 16.0 0.0 25 5.3 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain NleF_casp_inhib PF16809.5 RUS87917.1 - 0.056 13.4 0.5 17 5.3 0.1 3.4 3 1 0 3 3 3 0 NleF caspase inhibitor WWE PF02825.20 RUS87917.1 - 0.059 14.0 0.1 1.7 9.3 0.0 2.6 3 0 0 3 3 2 0 WWE domain p25-alpha PF05517.12 RUS87917.1 - 0.083 13.1 1.3 5.7 7.1 0.0 3.0 3 0 0 3 3 3 0 p25-alpha UPF0149 PF03695.13 RUS87917.1 - 0.29 11.4 2.6 0.49 10.7 0.2 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0149) RPAP3_C PF13877.6 RUS87917.1 - 1.6 9.3 5.2 0.39 11.3 0.3 2.6 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 tRNA-synt_2 PF00152.20 RUS87918.1 - 2.2e-78 263.5 0.1 3.3e-78 263.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RUS87918.1 - 3.8e-13 49.2 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RUS87918.1 - 7.1e-08 32.2 0.1 0.0027 17.2 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) MscS_TM PF12794.7 RUS87918.1 - 1.5 7.6 3.8 2.2 7.1 3.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Lectin_N PF03954.14 RUS87919.1 - 0.024 14.4 1.6 0.085 12.6 1.6 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain CBM_6 PF03422.15 RUS87919.1 - 0.089 13.1 5.1 25 5.2 0.2 3.6 1 1 3 4 4 4 0 Carbohydrate binding module (family 6) DUF1571 PF07608.11 RUS87919.1 - 0.17 11.3 0.6 19 4.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1571) GET2 PF08690.10 RUS87919.1 - 0.27 10.9 11.2 0.33 10.6 2.3 2.5 1 1 2 3 3 3 0 GET complex subunit GET2 Clat_adaptor_s PF01217.20 RUS87920.1 - 1.2 9.0 15.4 15 5.5 1.7 5.0 1 1 4 5 5 5 0 Clathrin adaptor complex small chain DUF1979 PF09322.10 RUS87920.1 - 6.9 6.7 18.4 30 4.6 0.1 6.9 1 1 8 9 9 9 0 Domain of unknown function (DUF1979) MFS_1 PF07690.16 RUS87921.1 - 6.8e-50 170.0 35.9 2.3e-39 135.4 26.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS87921.1 - 4.9e-07 29.0 25.8 9.8e-06 24.7 6.7 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 RUS87921.1 - 0.00091 18.1 19.5 0.0018 17.2 6.1 3.0 3 1 0 3 3 3 2 LacY proton/sugar symporter MFS_1_like PF12832.7 RUS87921.1 - 0.0012 17.8 2.7 0.0012 17.8 2.7 2.8 2 1 1 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 RUS87921.1 - 0.12 10.7 9.5 0.42 9.0 4.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2070 PF09843.9 RUS87921.1 - 0.16 10.2 0.0 0.16 10.2 0.0 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2070) zf-LITAF-like PF10601.9 RUS87921.1 - 1 9.7 3.2 10 6.4 0.9 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain EF-hand_6 PF13405.6 RUS87922.1 - 0.00013 21.6 11.0 1.1 9.3 0.0 4.2 2 2 2 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 RUS87922.1 - 0.0037 17.7 9.2 0.85 10.1 9.3 3.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS87922.1 - 0.046 13.3 14.2 1.4 8.6 0.2 4.2 2 2 2 4 4 4 0 EF hand EF-hand_5 PF13202.6 RUS87922.1 - 0.077 12.5 8.8 0.14 11.7 0.2 3.9 4 0 0 4 4 4 0 EF hand EF-hand_4 PF12763.7 RUS87922.1 - 0.56 10.2 2.8 0.37 10.8 0.3 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Myosin_head PF00063.21 RUS87923.1 - 1.9e-165 551.8 0.0 1.9e-165 551.8 0.0 3.0 3 0 0 3 3 3 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 RUS87923.1 - 1.9e-29 102.7 0.7 1.5e-27 96.4 0.1 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RUS87923.1 - 2.5e-12 47.1 2.8 2.5e-12 47.1 2.8 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RUS87923.1 - 1e-08 35.4 0.1 2.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AAA_16 PF13191.6 RUS87923.1 - 0.0012 19.2 0.0 0.0039 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Glycos_transf_2 PF00535.26 RUS87923.1 - 0.0055 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 AAA_22 PF13401.6 RUS87923.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 RUS87924.1 - 0.0013 18.7 9.7 0.0042 17.0 9.7 1.9 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PI3Ka PF00613.20 RUS87925.1 - 9.8e-48 162.0 0.8 9.8e-48 162.0 0.8 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RUS87925.1 - 4.1e-47 161.1 1.9 3e-32 112.4 0.1 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 RUS87925.1 - 3.5e-43 146.9 0.0 6.9e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 RUS87925.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.6 RUS87925.1 - 0.016 14.6 0.1 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) UDG PF03167.19 RUS87926.1 - 1.7e-24 86.5 0.0 2.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CBM_14 PF01607.24 RUS87928.1 - 1.1e-09 38.3 20.2 1.9e-08 34.3 2.0 3.3 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain Presenilin PF01080.17 RUS87928.1 - 0.11 11.3 19.5 0.14 10.9 19.5 1.2 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 RUS87928.1 - 0.11 11.4 11.0 0.13 11.1 11.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ndc1_Nup PF09531.10 RUS87928.1 - 0.26 9.9 15.4 0.35 9.5 15.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 RUS87928.1 - 0.56 8.0 18.8 0.69 7.8 18.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 RUS87928.1 - 2 8.2 19.8 2.8 7.7 19.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIN_3 PF13470.6 RUS87928.1 - 2.3 9.0 6.6 7.9 7.3 6.6 2.0 1 1 0 1 1 1 0 PIN domain TFIIA PF03153.13 RUS87928.1 - 2.3 8.1 48.8 4.3 7.2 48.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.13 RUS87928.1 - 2.4 9.0 12.4 3.5 8.4 12.4 1.2 1 0 0 1 1 1 0 Senescence regulator Neur_chan_memb PF02932.16 RUS87928.1 - 2.7 8.0 15.2 4.6 7.2 15.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 RUS87928.1 - 3.3 6.7 10.7 4.4 6.3 10.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein CBM_14 PF01607.24 RUS87929.1 - 2.2e-11 43.7 11.0 1.4e-05 25.1 1.0 2.7 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain I-set PF07679.16 RUS87930.1 - 1.7e-36 124.2 0.0 5.4e-16 58.4 0.0 3.1 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS87930.1 - 1.4e-34 118.5 0.1 6e-12 46.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS87930.1 - 2.9e-27 94.6 0.0 3.7e-11 43.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS87930.1 - 9.4e-22 77.3 1.2 4e-09 36.6 0.0 5.2 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS87930.1 - 1.8e-19 69.9 0.0 2.3e-06 27.9 0.0 3.2 2 1 1 3 3 3 3 Immunoglobulin domain Receptor_2B4 PF11465.8 RUS87930.1 - 8.3e-11 42.1 0.0 2.2e-06 27.8 0.0 4.0 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Ig_5 PF16681.5 RUS87930.1 - 8.2e-10 39.0 0.1 0.1 13.0 0.0 3.9 3 2 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS87930.1 - 7.4e-08 31.8 0.0 0.0026 17.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 RUS87930.1 - 1.8e-06 28.1 0.1 2.8 8.2 0.0 4.2 3 2 0 3 3 3 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS87930.1 - 4.1e-05 23.6 0.1 0.27 11.3 0.0 3.4 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 RUS87930.1 - 0.0096 14.7 0.1 0.89 8.2 0.0 2.4 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E Astacin PF01400.24 RUS87931.1 - 3.9e-22 78.8 0.0 5.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CAF1A PF12253.8 RUS87932.1 - 5.7e-23 80.9 11.1 5.7e-23 80.9 11.1 5.3 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF1-p150_C2 PF15539.6 RUS87932.1 - 1.9e-11 44.0 7.2 2.7e-05 23.8 0.0 4.4 2 1 1 3 3 3 2 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.8 RUS87932.1 - 1.6e-06 27.9 95.2 1.6e-06 27.9 95.2 3.4 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TRAM_LAG1_CLN8 PF03798.16 RUS87933.1 - 1.8e-39 135.5 29.1 1.8e-39 135.5 29.1 1.6 2 0 0 2 2 2 1 TLC domain Homeodomain PF00046.29 RUS87933.1 - 1.4e-09 37.6 0.3 3.2e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 RUS87933.1 - 0.0081 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez TRAM1 PF08390.11 RUS87933.1 - 0.032 13.9 0.1 0.032 13.9 0.1 3.0 4 0 0 4 4 4 0 TRAM1-like protein Homeobox_KN PF05920.11 RUS87933.1 - 0.058 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain TRI9 PF08195.11 RUS87933.1 - 0.12 12.2 0.4 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 TRI9 protein Tudor_2 PF18104.1 RUS87933.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.9 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain zf-C3HC4_2 PF13923.6 RUS87934.1 - 7.2e-11 41.7 6.3 1.4e-10 40.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS87934.1 - 1.3e-08 34.6 7.7 2.6e-08 33.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS87934.1 - 4.6e-06 26.9 6.3 9.1e-06 25.9 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS87934.1 - 9.2e-05 22.2 6.4 0.00018 21.3 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS87934.1 - 0.0001 22.2 6.4 0.00022 21.1 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS87934.1 - 0.00036 20.7 3.7 0.0011 19.2 3.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain RAWUL PF16207.5 RUS87934.1 - 0.0089 16.7 0.0 0.028 15.1 0.0 1.9 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Prok-RING_4 PF14447.6 RUS87934.1 - 0.028 14.3 5.5 0.064 13.1 5.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS87934.1 - 0.058 13.6 9.6 0.13 12.5 9.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RUS87934.1 - 0.087 12.9 7.1 0.22 11.6 7.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 RUS87934.1 - 0.15 12.2 3.5 0.34 11.1 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 RUS87934.1 - 0.83 9.5 2.9 2 8.3 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RUS87934.1 - 0.87 9.5 2.8 1.9 8.4 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 RUS87934.1 - 6.8 6.4 7.6 17 5.2 7.6 1.7 1 0 0 1 1 1 0 P-11 zinc finger Tetraspanin PF00335.20 RUS87935.1 - 3.6 7.2 8.1 7.4 6.2 8.1 1.4 1 0 0 1 1 1 0 Tetraspanin family RAWUL PF16207.5 RUS87936.1 - 1.9e-14 54.1 0.0 3.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 RUS87936.1 - 9.7e-10 38.1 8.1 1.7e-09 37.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS87936.1 - 2.3e-09 37.0 8.4 4.3e-09 36.1 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS87936.1 - 1.2e-06 28.8 7.4 2.4e-06 27.8 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS87936.1 - 3.1e-06 26.9 6.3 5.7e-06 26.1 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RUS87936.1 - 0.00019 21.7 3.7 0.00039 20.7 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RUS87936.1 - 0.00039 20.3 9.3 0.0012 18.8 9.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS87936.1 - 0.00081 19.4 6.0 0.0016 18.4 6.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 RUS87936.1 - 0.0038 17.3 4.8 0.012 15.8 4.8 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 RUS87936.1 - 0.0051 16.9 8.7 0.01 16.0 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS87936.1 - 0.0086 15.9 7.0 0.017 15.0 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 RUS87936.1 - 0.057 13.2 3.0 0.13 12.1 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 RUS87936.1 - 0.21 11.3 5.1 0.45 10.2 5.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-UDP PF14569.6 RUS87936.1 - 0.25 11.5 5.7 0.94 9.6 5.7 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 RUS87936.1 - 0.5 10.2 5.3 1.3 8.8 5.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 RUS87936.1 - 5.1 7.0 8.5 1.2 9.1 4.1 2.2 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 RUS87936.1 - 8.3 6.6 8.6 33 4.7 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Dicer_N PF17895.1 RUS87938.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain RAWUL PF16207.5 RUS87939.1 - 2.4e-09 37.7 0.3 5.2e-09 36.7 0.3 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 RUS87939.1 - 3.8e-07 29.9 4.2 1.3e-06 28.2 4.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS87939.1 - 6.4e-06 25.9 3.2 2e-05 24.3 3.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS87939.1 - 0.0013 18.7 4.1 0.0045 17.0 4.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS87939.1 - 0.0031 17.6 4.4 0.0031 17.6 4.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RUS87939.1 - 0.008 16.5 3.8 0.021 15.1 3.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS87939.1 - 0.58 10.2 6.0 2.5 8.1 5.9 2.2 1 1 0 1 1 1 0 zinc-RING finger domain PIP5K PF01504.18 RUS87940.1 - 4.4e-41 140.9 0.5 5e-41 140.7 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Beta-lactamase PF00144.24 RUS87941.1 - 6.3e-24 84.8 0.0 9.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Phage_holin_2_1 PF04971.12 RUS87941.1 - 0.4 10.7 2.5 8.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S WD40 PF00400.32 RUS87942.1 - 2e-17 63.2 7.1 0.00012 22.8 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat 7tm_1 PF00001.21 RUS87943.1 - 2.9e-06 26.8 5.4 3.3e-06 26.6 5.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS87943.1 - 0.0013 18.4 10.6 0.0015 18.2 10.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 RUS87943.1 - 0.0049 16.8 2.9 0.0069 16.4 2.8 1.5 1 1 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa Vault PF01505.18 RUS87944.1 - 1.3e-59 198.1 3.1 7.5e-16 58.0 0.0 4.9 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 RUS87944.1 - 2.5e-55 185.6 0.2 5.1e-55 184.6 0.2 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 RUS87944.1 - 2.6e-39 133.4 0.4 4.9e-24 84.5 0.2 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 RUS87944.1 - 3.4e-37 126.3 2.7 2.9e-33 113.7 0.0 4.4 3 1 1 4 4 4 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 RUS87944.1 - 5.8e-27 93.5 0.3 6.8e-26 90.1 0.1 3.0 4 0 0 4 4 4 1 Major Vault Protein repeat domain B3_4 PF03483.17 RUS87944.1 - 0.00054 19.7 0.8 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 B3/4 domain MDM10 PF12519.8 RUS87944.1 - 7.7 5.3 6.8 12 4.6 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Lectin_C PF00059.21 RUS87945.1 - 1.8e-28 99.4 14.9 4.8e-12 46.6 0.5 4.3 4 0 0 4 4 4 3 Lectin C-type domain UL45 PF05473.12 RUS87945.1 - 0.00039 20.1 0.1 0.00039 20.1 0.1 3.8 3 2 0 3 3 3 1 UL45 protein, carbohydrate-binding C-type lectin-like Transglut_N PF00868.20 RUS87946.1 - 3.9e-38 130.4 0.0 4.4e-36 123.8 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase family Transglut_C PF00927.22 RUS87946.1 - 1.4e-18 66.9 0.0 5.3e-08 33.0 0.0 2.8 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 RUS87946.1 - 4.6e-16 59.3 0.4 1.1e-15 58.1 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Tail_tube PF10618.9 RUS87946.1 - 0.12 12.2 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Phage tail tube protein UPF0086 PF01868.16 RUS87947.1 - 3.6e-14 52.5 0.0 7.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SapB_2 PF03489.17 RUS87947.1 - 0.01 15.9 0.2 0.028 14.5 0.2 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 2 Cu-binding_MopE PF11617.8 RUS87947.1 - 0.12 12.5 0.1 0.42 10.8 0.1 2.0 1 0 0 1 1 1 0 Putative metal-binding motif PARP PF00644.20 RUS87948.1 - 9e-67 224.5 0.0 1.7e-66 223.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 RUS87948.1 - 1.8e-49 167.3 0.8 4.7e-49 166.0 0.8 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 RUS87948.1 - 6.6e-26 90.2 3.4 6.6e-26 90.2 3.4 2.7 3 0 0 3 3 3 1 WGR domain WWE PF02825.20 RUS87948.1 - 7.5e-26 90.5 0.2 3.4e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 WWE domain Neur_chan_LBD PF02931.23 RUS87949.1 - 5.2e-69 232.0 2.7 6.8e-69 231.6 2.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS87949.1 - 7.5e-47 160.4 0.4 3.2e-41 142.0 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U4 PF03419.13 RUS87949.1 - 0.099 11.9 1.0 0.18 11.0 1.0 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SHIRT PF18655.1 RUS87949.1 - 0.15 12.7 0.1 0.33 11.6 0.1 1.5 1 0 0 1 1 1 0 SHIRT domain zf-C2H2_10 PF16588.5 RUS87952.1 - 0.29 10.9 1.3 0.6 9.9 1.3 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger C2 PF00168.30 RUS87953.1 - 9.5e-21 74.0 0.7 4.6e-13 49.3 0.1 2.2 2 0 0 2 2 2 2 C2 domain ASCH PF04266.14 RUS87953.1 - 0.1 13.2 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 ASCH domain BIR PF00653.21 RUS87954.1 - 1.1e-33 115.7 14.5 1.6e-22 79.9 0.6 3.1 4 0 0 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS87954.1 - 8.7e-11 41.5 15.7 1.9e-10 40.4 7.3 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS87954.1 - 4.2e-06 26.5 7.6 4.2e-06 26.5 7.6 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS87954.1 - 0.0051 16.7 9.0 0.0051 16.7 9.0 2.9 2 1 0 2 2 2 1 zinc-RING finger domain DUF2039 PF10217.9 RUS87954.1 - 3.9 7.9 14.6 2.3 8.6 5.3 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Cytochrom_B561 PF03188.16 RUS87955.1 - 4.2e-26 91.7 6.0 4.2e-26 91.7 6.0 1.7 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2231 PF09990.9 RUS87955.1 - 3.6 8.1 11.8 0.39 11.2 0.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) DUF3021 PF11457.8 RUS87955.1 - 7.6 6.9 17.9 1.1 9.5 1.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3021) CDC45 PF02724.14 RUS87957.1 - 3.8e-05 22.2 12.6 4.7e-05 21.9 12.6 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS87957.1 - 0.00026 20.5 21.4 0.00029 20.4 21.4 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS87957.1 - 0.052 11.8 30.2 0.062 11.5 30.2 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS87957.1 - 0.42 8.7 47.2 0.51 8.4 47.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RUS87957.1 - 0.89 7.9 22.9 1.1 7.6 22.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Drc1-Sld2 PF11719.8 RUS87957.1 - 4.1 6.8 8.0 4.5 6.7 8.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop53 PF07767.11 RUS87957.1 - 5.8 6.2 9.3 9.1 5.5 9.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4637 PF15470.6 RUS87957.1 - 6.3 6.5 16.2 11 5.7 16.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nrf1_DNA-bind PF10491.9 RUS87958.1 - 6.6e-08 32.5 0.1 1.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2841 PF11001.8 RUS87958.1 - 6.4e-07 29.5 0.4 1.6e-06 28.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) zf-MYST PF17772.1 RUS87958.1 - 0.068 12.8 1.5 0.14 11.8 1.5 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain DUF4660 PF15559.6 RUS87959.1 - 0.0017 18.6 0.2 5.3 7.4 0.1 3.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4660) Keratin_B2 PF01500.17 RUS87959.1 - 0.046 13.7 0.6 1.9 8.5 0.5 2.1 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein DUF5352 PF17303.2 RUS87959.1 - 0.17 11.7 3.2 4.5 7.1 0.3 3.3 1 1 3 4 4 4 0 Family of unknown function (DUF5352) zf-RING_2 PF13639.6 RUS87961.1 - 0.00058 20.1 13.1 0.0011 19.2 13.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS87961.1 - 0.016 15.2 9.2 0.035 14.2 9.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FliJ PF02050.16 RUS87961.1 - 0.045 14.0 5.8 0.072 13.3 5.8 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein zf-C3HC4_2 PF13923.6 RUS87961.1 - 0.049 13.5 12.3 0.11 12.4 12.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.12 RUS87961.1 - 0.092 12.8 8.6 0.42 10.7 8.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) RmuC PF02646.16 RUS87961.1 - 0.29 10.2 1.5 0.49 9.5 1.5 1.4 1 0 0 1 1 1 0 RmuC family T2SSF PF00482.23 RUS87961.1 - 0.47 10.4 3.3 0.82 9.6 3.3 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F zf-C3HC4 PF00097.25 RUS87961.1 - 0.57 10.1 13.8 1.1 9.1 13.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS87961.1 - 0.8 9.9 12.4 1.6 9.0 12.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Amnionless PF14828.6 RUS87962.1 - 0.032 13.1 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 RUS87962.1 - 0.038 14.9 0.2 0.18 12.7 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 RUS87962.1 - 0.08 13.0 0.6 0.15 12.1 0.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Cytomega_UL84 PF06284.11 RUS87962.1 - 0.16 10.4 4.0 0.27 9.6 4.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein UPF0239 PF06783.11 RUS87964.1 - 4.2e-18 65.3 0.1 5.3e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) RNase_H PF00075.24 RUS87965.1 - 3e-11 43.7 0.0 7.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 RUS87965.1 - 1.1e-07 32.5 1.4 3.3e-07 30.9 0.8 2.1 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 RUS87965.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.27 RUS87965.1 - 0.028 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) YdjO PF14169.6 RUS87965.1 - 0.12 12.1 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 Cold-inducible protein YdjO Ras PF00071.22 RUS87966.1 - 1e-95 317.8 0.0 3.7e-57 192.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RUS87966.1 - 5.4e-37 126.7 0.0 1.5e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS87966.1 - 3e-14 52.9 0.0 8.6e-09 35.1 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS87966.1 - 8.6e-09 35.2 0.0 0.0011 18.6 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain HGTP_anticodon PF03129.20 RUS87966.1 - 0.00067 19.8 0.3 0.055 13.6 0.1 2.4 2 0 0 2 2 2 1 Anticodon binding domain LAG1-DNAbind PF09271.11 RUS87966.1 - 0.0026 18.4 0.2 1.4 9.5 0.1 2.2 2 0 0 2 2 2 2 LAG1, DNA binding MeaB PF03308.16 RUS87966.1 - 0.0057 15.7 0.3 0.49 9.3 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PK_C PF02887.16 RUS87966.1 - 0.013 15.7 0.1 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain SRPRB PF09439.10 RUS87966.1 - 0.042 13.3 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit VASP_tetra PF08776.11 RUS87966.1 - 0.042 13.4 4.0 2.2 7.9 0.4 2.5 2 0 0 2 2 2 0 VASP tetramerisation domain Gtr1_RagA PF04670.12 RUS87966.1 - 0.055 12.8 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NPH-II PF12011.8 RUS87966.1 - 0.13 12.2 0.1 13 5.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NPH-II DUF498 PF04430.14 RUS87967.1 - 4.4e-09 36.4 0.0 6.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Acyltransferase PF01553.21 RUS87968.1 - 5.6e-25 87.5 0.0 6.9e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase 2Fe-2S_thioredx PF01257.19 RUS87968.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin zf-C2H2 PF00096.26 RUS87971.1 - 7.7e-18 63.9 92.9 0.0004 20.7 0.5 10.8 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS87971.1 - 3.6e-09 36.6 91.7 0.0017 18.7 3.0 10.3 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS87971.1 - 8.9e-09 35.5 94.6 0.0033 18.1 0.3 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS87971.1 - 3.2e-07 30.0 61.1 0.016 15.0 2.6 7.5 7 0 0 7 7 7 5 C2H2-type zinc-finger domain Tcp10_C PF07202.13 RUS87971.1 - 0.00089 19.3 1.3 0.00089 19.3 1.3 4.8 3 2 2 6 6 6 2 T-complex protein 10 C-terminus zf-C2H2_jaz PF12171.8 RUS87971.1 - 0.0091 16.3 0.0 0.0091 16.3 0.0 8.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS87971.1 - 0.032 14.2 0.1 0.032 14.2 0.1 7.4 8 1 0 8 8 8 0 C2H2-type zinc finger zf-met PF12874.7 RUS87971.1 - 4.1 7.9 50.7 0.27 11.7 0.1 9.9 8 1 0 9 9 9 0 Zinc-finger of C2H2 type MbeB_N PF04837.12 RUS87974.1 - 2.4e-05 24.5 2.6 13 6.1 0.1 4.4 1 1 6 7 7 7 7 MbeB-like, N-term conserved region CnrY PF17524.2 RUS87974.1 - 0.0013 18.9 1.4 1.4 9.1 0.1 3.0 1 1 2 3 3 3 2 Anti-sigma factor CnrY LEM PF03020.15 RUS87974.1 - 0.024 14.2 2.2 1.1e+02 2.5 0.1 5.8 1 1 5 6 6 6 0 LEM domain DUF4938 PF16292.5 RUS87974.1 - 0.13 11.5 0.1 3.1 7.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4938) ATP-synt_S1 PF05827.12 RUS87975.1 - 4.5e-36 123.9 0.0 7.6e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Ribosom_S12_S23 PF00164.25 RUS87976.1 - 8.6e-53 176.8 0.5 1.2e-52 176.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2502 PF10697.9 RUS87976.1 - 0.15 12.4 8.3 0.24 11.8 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Sulfotransfer_4 PF17784.1 RUS87977.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain ECH_2 PF16113.5 RUS87977.1 - 1.1 8.7 3.7 1.6 8.1 3.7 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase TMPIT PF07851.13 RUS87977.1 - 4 6.6 6.7 6.7 5.9 6.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 RUS87978.1 - 0.75 9.8 8.7 0.32 11.0 6.0 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HDNR PF15115.6 RUS87979.1 - 1.1e-24 87.7 4.6 1.4e-24 87.3 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif DBD_Tnp_Mut PF03108.15 RUS87979.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 MuDR family transposase Pkinase PF00069.25 RUS87980.1 - 4.5e-38 131.1 8.0 1.3e-20 73.9 0.8 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS87980.1 - 6.9e-10 38.6 5.7 1.1e-08 34.7 0.2 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Usp PF00582.26 RUS87981.1 - 2.6e-30 105.8 0.2 3.2e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF5136 PF17199.4 RUS87981.1 - 0.16 11.7 1.0 0.28 10.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) Sld5 PF05916.11 RUS87982.1 - 0.57 10.7 6.0 0.27 11.7 3.1 1.9 2 0 0 2 2 2 0 GINS complex protein SDA1 PF05285.12 RUS87983.1 - 0.0067 15.9 29.9 0.0088 15.5 29.9 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 RUS87983.1 - 0.083 12.2 28.6 0.11 11.8 28.6 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 RUS87983.1 - 0.25 11.0 58.2 0.24 11.1 19.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 RUS87983.1 - 0.51 9.1 6.8 0.57 8.9 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 RUS87983.1 - 0.68 8.0 61.1 0.23 9.5 29.3 2.0 2 0 0 2 2 2 0 DNA polymerase phi Vfa1 PF08432.10 RUS87983.1 - 3.9 7.8 11.0 6.6 7.0 2.6 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 RUS87984.1 - 0.00065 18.4 7.3 0.00065 18.4 7.3 2.8 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 RUS87984.1 - 0.0027 15.9 24.0 0.0027 15.9 24.0 3.0 2 1 1 3 3 3 1 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 RUS87984.1 - 0.19 12.2 3.2 8.6 6.8 1.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF913 PF06025.12 RUS87984.1 - 8.2 5.3 10.1 10 5.0 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CC PF04942.14 RUS87985.1 - 0.069 13.4 0.1 1.3e+02 2.9 0.0 3.7 4 0 0 4 4 4 0 CC domain Fer2_2 PF01799.20 RUS87985.1 - 0.13 12.3 0.1 3.1 7.9 0.1 2.7 1 1 0 1 1 1 0 [2Fe-2S] binding domain zf-RING_7 PF02591.15 RUS87991.1 - 3.5e-06 27.1 1.5 54 4.1 0.0 6.5 6 1 1 7 7 7 0 C4-type zinc ribbon domain NADH_dh_m_C1 PF15088.6 RUS87991.1 - 0.0036 16.9 15.5 11 5.8 0.9 5.3 1 1 4 5 5 5 5 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Cas_csx3 PF09620.10 RUS87991.1 - 2.4 8.1 8.8 14 5.7 0.3 3.0 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_csx3) Gp5_OB PF06714.11 RUS87991.1 - 6 7.1 5.3 20 5.4 0.2 2.8 1 1 2 3 3 3 0 Gp5 N-terminal OB domain MACPF PF01823.19 RUS87992.1 - 1.3e-21 77.7 0.0 1.8e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 MAC/Perforin domain Ribosomal_L24e PF01246.20 RUS87993.1 - 1.1e-30 105.7 5.4 1.1e-30 105.7 5.4 1.9 2 1 1 3 3 3 1 Ribosomal protein L24e DUF2116 PF09889.9 RUS87993.1 - 0.9 9.6 5.7 0.86 9.6 1.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ras PF00071.22 RUS87994.1 - 4.1e-44 150.0 0.1 5e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS87994.1 - 1.1e-30 106.3 0.3 1.5e-30 105.8 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS87994.1 - 1.9e-11 43.7 0.3 2.6e-11 43.3 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS87994.1 - 1.7e-05 24.3 0.2 1.9e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS87994.1 - 2.8e-05 24.2 0.0 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS87994.1 - 0.0039 16.6 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS87994.1 - 0.0065 16.0 0.0 0.045 13.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RUS87994.1 - 0.042 13.6 0.5 3.3 7.4 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Mfa_like_2 PF15415.6 RUS87994.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin-like zf_Hakai PF18408.1 RUS87995.1 - 4.6e-12 45.4 5.5 4.6e-12 45.4 5.5 1.8 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain zf-C3HC4_3 PF13920.6 RUS87995.1 - 0.015 15.2 12.8 0.026 14.4 12.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS87995.1 - 0.079 12.9 11.7 0.15 12.0 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 RUS87995.1 - 0.22 11.4 11.1 0.48 10.3 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS87995.1 - 1.7 9.1 12.4 3.2 8.2 12.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 RUS87995.1 - 1.9 8.6 9.4 4.6 7.4 9.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS87995.1 - 2.5 8.0 11.5 5.7 6.9 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ldl_recept_a PF00057.18 RUS87996.1 - 8.8e-54 179.4 94.8 1.3e-13 50.9 12.4 5.3 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A PyrI_C PF02748.15 RUS87996.1 - 0.45 10.5 9.8 1.4 8.9 0.3 4.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain LisH PF08513.11 RUS87998.1 - 0.015 15.2 0.8 0.44 10.6 0.0 3.3 4 0 0 4 4 4 0 LisH DUF913 PF06025.12 RUS87998.1 - 0.048 12.6 3.3 0.18 10.7 0.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) LisH_TPL PF17814.1 RUS87998.1 - 0.67 9.7 7.4 0.54 10.0 0.7 3.3 3 0 0 3 3 3 0 LisH-like dimerisation domain Plant_NMP1 PF06694.11 RUS87999.1 - 1.2e-05 24.6 0.0 5.9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) KxDL PF10241.9 RUS87999.1 - 0.16 12.3 0.6 0.7 10.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein Nuc_sug_transp PF04142.15 RUS88000.1 - 5.3e-125 416.7 25.8 6.2e-125 416.5 25.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 RUS88000.1 - 6.9e-07 28.8 31.1 1.2e-05 24.7 16.3 2.6 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.20 RUS88000.1 - 1.1e-05 25.7 31.7 0.0062 16.7 12.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 RUS88000.1 - 0.02 14.5 15.0 0.04 13.5 13.4 2.4 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter Mon1 PF03164.14 RUS88000.1 - 0.1 11.6 2.5 0.097 11.7 0.5 1.8 2 0 0 2 2 2 0 Trafficking protein Mon1 PUNUT PF16913.5 RUS88000.1 - 3.6 6.7 28.6 6.9 5.8 28.6 1.4 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport CHCH PF06747.13 RUS88001.1 - 2e-05 24.6 0.8 4.2e-05 23.6 0.8 1.6 1 0 0 1 1 1 1 CHCH domain Keratin_B2 PF01500.17 RUS88002.1 - 7e-17 61.9 84.9 0.00012 22.1 47.3 5.5 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.6 RUS88002.1 - 5.9e-07 29.3 91.5 0.058 13.3 12.8 5.7 1 1 2 3 3 3 1 Keratin, high sulfur B2 protein eIF-3_zeta PF05091.12 RUS88004.1 - 1.6e-65 222.1 0.1 1.8e-65 221.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 RUS88004.1 - 0.00079 19.0 0.0 0.00093 18.8 0.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Pes-10 PF07149.11 RUS88004.1 - 0.012 14.7 7.6 0.015 14.4 7.6 1.1 1 0 0 1 1 1 0 Pes-10 PPP4R2 PF09184.11 RUS88004.1 - 0.021 14.4 6.2 0.021 14.5 6.2 1.1 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 RUS88004.1 - 0.047 13.7 6.0 0.058 13.4 6.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 RUS88004.1 - 0.2 11.0 7.6 0.21 11.0 7.6 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 RUS88004.1 - 0.37 10.1 19.7 0.45 9.8 19.7 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 RUS88004.1 - 0.37 9.0 8.5 0.43 8.8 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.12 RUS88004.1 - 0.61 8.0 5.6 0.59 8.0 5.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sigma70_ner PF04546.13 RUS88004.1 - 1.1 9.1 12.3 1.5 8.6 12.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 RUS88004.1 - 1.2 8.8 21.8 0.68 9.6 20.3 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 RUS88004.1 - 4.4 5.7 10.9 4.7 5.6 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 RUS88004.1 - 8.6 5.9 8.5 12 5.4 8.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting LIM PF00412.22 RUS88005.1 - 5e-14 52.3 2.0 5.4e-14 52.2 2.0 1.1 1 0 0 1 1 1 1 LIM domain Metallothio_Pro PF02069.16 RUS88005.1 - 0.004 17.3 1.9 0.0055 16.9 1.9 1.2 1 0 0 1 1 1 1 Prokaryotic metallothionein Pea-VEAacid PF08111.11 RUS88005.1 - 0.086 13.2 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 Pea-VEAacid family zf_UBZ PF18439.1 RUS88005.1 - 3.4 7.3 9.0 0.19 11.3 2.2 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RNA_pol_Rbc25 PF08292.12 RUS88006.1 - 1e-38 132.5 0.0 1.4e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 RUS88006.1 - 4.4e-17 62.2 0.0 6.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.25 RUS88007.1 - 5.1e-20 71.9 0.0 1.3e-12 47.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88007.1 - 2.5e-13 49.9 0.0 1.1e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 RUS88007.1 - 0.061 12.7 1.2 0.092 12.1 1.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS88007.1 - 0.098 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 RUS88008.1 - 6.4e-29 101.1 0.0 7.8e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88008.1 - 3.9e-20 72.2 0.0 4.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88008.1 - 0.008 15.6 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS88008.1 - 0.034 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RUS88008.1 - 0.084 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sulfotransfer_1 PF00685.27 RUS88009.1 - 1.9e-21 76.8 1.7 4.6e-21 75.5 1.7 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS88009.1 - 6.2e-17 62.7 0.3 1.9e-16 61.1 0.3 1.8 1 1 0 1 1 1 1 Sulfotransferase family Reprolysin PF01421.19 RUS88011.1 - 9.2e-09 35.5 0.0 2.8e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 RUS88011.1 - 6e-08 33.1 0.1 2.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS88011.1 - 3.8e-07 30.7 0.0 1.2e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS88011.1 - 9.9e-05 22.1 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS88011.1 - 0.00016 21.6 0.3 0.00031 20.7 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS88011.1 - 0.035 14.3 1.0 0.035 14.3 1.0 1.7 2 0 0 2 2 2 0 Reprolysin family propeptide OATP PF03137.20 RUS88015.1 - 3e-27 95.1 2.0 4.2e-27 94.6 2.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family S4_2 PF13275.6 RUS88015.1 - 0.052 13.4 0.1 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 S4 domain Pam17 PF08566.10 RUS88015.1 - 0.11 12.4 0.3 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 OATP PF03137.20 RUS88016.1 - 1.8e-44 152.0 9.6 2e-44 151.8 9.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS88016.1 - 3.4e-07 29.5 19.1 0.00024 20.1 3.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4976 PF16347.5 RUS88017.1 - 0.0013 19.0 0.6 0.002 18.3 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) WH1 PF00568.23 RUS88017.1 - 0.034 14.1 0.7 0.046 13.7 0.7 1.2 1 0 0 1 1 1 0 WH1 domain DUF4834 PF16118.5 RUS88017.1 - 0.16 13.0 0.0 0.21 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUP PF00674.18 RUS88017.1 - 0.67 10.1 10.8 0.034 14.3 5.4 1.6 2 0 0 2 2 2 0 DUP family DUF3740 PF12548.8 RUS88018.1 - 4.5e-15 56.4 3.5 7.7e-15 55.6 3.5 1.4 1 1 0 1 1 1 1 Sulfatase protein Vpu PF00558.19 RUS88018.1 - 0.022 14.5 0.4 0.022 14.5 0.4 1.9 2 0 0 2 2 2 0 Vpu protein HOOK PF05622.12 RUS88018.1 - 0.049 11.8 0.3 0.065 11.4 0.3 1.1 1 0 0 1 1 1 0 HOOK protein Sulfatase PF00884.23 RUS88019.1 - 3.3e-16 59.6 0.1 3.9e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Sulfatase PF00884.23 RUS88020.1 - 7.6e-49 166.8 6.0 1.8e-39 135.9 3.1 2.1 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.17 RUS88020.1 - 0.00092 17.9 0.1 0.0016 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 RUS88020.1 - 0.0019 17.9 1.2 0.086 12.4 0.0 2.5 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase PRCC PF10253.9 RUS88020.1 - 0.045 14.5 3.8 0.074 13.8 1.3 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting APOC4 PF15119.6 RUS88020.1 - 0.22 11.8 2.3 0.48 10.7 0.1 2.7 3 0 0 3 3 3 0 Apolipoprotein C4 Secretin_N_2 PF07655.13 RUS88020.1 - 2.4 8.7 12.8 12 6.5 6.9 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain GTP_EFTU_D4 PF14578.6 RUS88026.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Nop53 PF07767.11 RUS88026.1 - 0.013 14.9 26.3 0.018 14.5 26.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.13 RUS88026.1 - 0.32 9.5 31.5 0.39 9.2 31.5 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 RUS88026.1 - 5.4 5.4 22.3 6.8 5.1 22.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF4590 PF15257.6 RUS88027.1 - 6e-41 138.9 0.8 1.2e-40 137.9 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) DUF4542 PF15075.6 RUS88027.1 - 0.0041 17.5 0.2 0.012 16.0 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4542) PLAC8 PF04749.17 RUS88028.1 - 1.3e-11 45.3 19.1 2e-11 44.7 19.1 1.3 1 0 0 1 1 1 1 PLAC8 family Aminotran_5 PF00266.19 RUS88029.1 - 0.013 14.5 0.0 0.052 12.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V DUF3361 PF11841.8 RUS88031.1 - 0.022 14.7 0.1 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) F-112 PF09645.10 RUS88031.1 - 0.028 14.5 0.3 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 F-112 protein HTH_psq PF05225.16 RUS88033.1 - 6.1e-10 38.7 0.1 2.1e-09 37.0 0.1 2.0 1 0 0 1 1 1 1 helix-turn-helix, Psq domain GH-E PF14410.6 RUS88033.1 - 0.037 14.4 0.0 17 5.9 0.0 2.5 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DsrD PF08679.11 RUS88033.1 - 0.49 10.7 1.5 45 4.4 0.1 2.7 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) HTH_Tnp_Tc5 PF03221.16 RUS88034.1 - 0.065 13.3 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain SSF PF00474.17 RUS88035.1 - 2.4e-34 118.9 28.1 2.4e-34 118.9 28.1 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Gly-zipper_YMGG PF13441.6 RUS88035.1 - 0.62 9.8 3.3 2.1 8.1 3.3 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 RUS88035.1 - 3.4 7.5 5.4 7.3 6.5 4.5 2.1 1 1 0 1 1 1 0 Glycine-zipper domain Laminin_G_1 PF00054.23 RUS88036.1 - 1.1e-14 54.8 0.0 1.4e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 RUS88036.1 - 1.3e-13 51.6 0.0 8.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_EGF PF00053.24 RUS88037.1 - 3.4e-98 321.6 313.7 2.4e-09 37.2 11.1 16.6 16 0 0 16 16 16 16 Laminin EGF domain Laminin_G_2 PF02210.24 RUS88037.1 - 4.7e-39 133.8 0.1 1.5e-13 51.4 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 RUS88037.1 - 8.6e-35 119.8 1.2 1.5e-13 51.1 0.0 4.0 4 0 0 4 4 4 3 Laminin G domain Laminin_B PF00052.18 RUS88037.1 - 5.4e-13 49.0 0.0 2.7e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 Laminin B (Domain IV) FIN1 PF17300.2 RUS88037.1 - 0.71 9.3 3.1 1.3 8.5 3.1 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Sugarporin_N PF11471.8 RUS88037.1 - 0.89 9.6 4.7 4.6 7.3 4.7 2.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Med9 PF07544.13 RUS88037.1 - 2 8.6 10.0 0.41 10.8 3.9 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SSF PF00474.17 RUS88038.1 - 1.1e-40 139.7 25.9 1.4e-40 139.4 25.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Exo_endo_phos_2 PF14529.6 RUS88039.1 - 1.1e-16 60.7 0.0 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS88039.1 - 9.7e-16 58.0 0.3 2.3e-15 56.7 0.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aldedh PF00171.22 RUS88040.1 - 5.5e-178 592.2 0.3 6.2e-178 592.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1350 PF07082.11 RUS88040.1 - 0.19 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) UPF0515 PF15135.6 RUS88042.1 - 8.6e-29 100.7 14.0 5.3e-26 91.6 8.8 2.0 1 1 1 2 2 2 2 Uncharacterised protein UPF0515 zf-3CxxC_2 PF17180.4 RUS88042.1 - 0.051 14.3 14.5 0.79 10.5 5.0 2.6 3 0 0 3 3 3 0 Zinc-binding domain zf-C3HC4 PF00097.25 RUS88042.1 - 0.8 9.6 5.9 0.83 9.6 2.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.20 RUS88042.1 - 1 9.5 7.8 0.76 10.0 5.9 1.8 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Cytochrom_c3_2 PF14537.6 RUS88042.1 - 1.1 9.8 6.5 0.25 11.8 1.8 2.1 1 1 0 2 2 2 0 Cytochrome c3 START PF01852.19 RUS88043.1 - 9.9e-20 70.8 0.9 1.5e-19 70.2 0.9 1.3 1 0 0 1 1 1 1 START domain Importin_rep PF18773.1 RUS88043.1 - 0.039 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat DUF3074 PF11274.8 RUS88043.1 - 0.063 13.2 1.0 0.12 12.3 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) rve PF00665.26 RUS88044.1 - 0.028 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Cas3_C PF18395.1 RUS88044.1 - 0.12 12.9 0.0 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 Cas3 C-terminal domain Glyco_transf_10 PF00852.19 RUS88045.1 - 2.1e-45 154.6 2.3 3.4e-45 153.9 2.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS88045.1 - 7.4e-12 45.7 0.2 2.3e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Mitofilin PF09731.9 RUS88046.1 - 9.4 4.9 62.1 11 4.7 62.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DAGK_cat PF00781.24 RUS88047.1 - 3.6e-25 88.0 0.0 7.7e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cwf_Cwc_15 PF04889.12 RUS88047.1 - 0.002 17.9 4.4 0.002 17.9 4.4 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein NAD_kinase PF01513.21 RUS88047.1 - 0.035 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase RPN6_N PF18055.1 RUS88048.1 - 3.8e-38 130.4 1.5 3.8e-38 130.4 1.5 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 RUS88048.1 - 1.8e-17 63.8 0.7 1.6e-16 60.7 0.6 2.5 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 RUS88048.1 - 5.1e-15 54.9 0.3 1e-14 53.9 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 RUS88048.1 - 0.043 14.1 4.5 0.6 10.4 1.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 RUS88048.1 - 0.21 11.3 3.7 0.29 10.8 2.6 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain RHH_5 PF07878.11 RUS88048.1 - 0.67 9.9 3.8 14 5.6 0.2 3.2 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Ank_2 PF12796.7 RUS88049.1 - 4.4e-77 254.7 27.2 8.2e-17 61.6 0.2 6.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 RUS88049.1 - 7.3e-53 174.8 22.2 6.5e-05 23.2 0.0 13.1 12 1 1 13 13 13 13 Ankyrin repeat Ank_4 PF13637.6 RUS88049.1 - 9.6e-52 172.7 18.8 8e-10 39.1 0.0 9.6 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS88049.1 - 1.1e-45 153.1 27.9 1.7e-08 34.6 0.7 10.3 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88049.1 - 1.1e-45 148.3 22.1 0.00082 19.6 0.0 12.7 13 0 0 13 13 13 11 Ankyrin repeat MauJ PF17419.2 RUS88049.1 - 0.00011 21.8 0.7 0.026 14.0 0.2 2.4 2 0 0 2 2 2 2 Methylamine utilization protein MauJ Utp13 PF08625.11 RUS88049.1 - 0.043 13.7 0.5 0.31 10.9 0.0 2.5 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain DUF1664 PF07889.12 RUS88050.1 - 1.7e-05 24.8 6.3 0.0009 19.3 1.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) LXG PF04740.12 RUS88050.1 - 0.00018 21.3 5.1 0.0043 16.8 3.0 2.6 2 1 0 2 2 2 1 LXG domain of WXG superfamily CCDC-167 PF15188.6 RUS88050.1 - 0.00074 19.8 2.6 0.0014 18.9 0.3 2.2 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.12 RUS88050.1 - 0.0012 18.9 5.0 0.02 15.0 1.6 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 RUS88050.1 - 0.0013 19.0 5.6 1.3 9.4 1.3 3.2 1 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 RUS88050.1 - 0.0021 18.1 3.7 0.42 10.6 0.7 2.3 1 1 1 2 2 2 2 Laminin Domain II ZapB PF06005.12 RUS88050.1 - 0.0026 18.2 0.9 2.3 8.7 0.1 2.6 2 1 0 2 2 2 1 Cell division protein ZapB Cluap1 PF10234.9 RUS88050.1 - 0.0031 17.0 5.8 0.009 15.4 1.7 2.1 1 1 1 2 2 2 1 Clusterin-associated protein-1 KASH_CCD PF14662.6 RUS88050.1 - 0.0059 16.5 4.1 0.013 15.3 4.1 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 RUS88050.1 - 0.0065 16.9 2.8 0.11 12.9 0.2 2.4 1 1 0 2 2 2 1 Snapin/Pallidin FlaC_arch PF05377.11 RUS88050.1 - 0.0071 16.7 8.4 3.6 8.0 0.1 3.6 3 1 1 4 4 3 1 Flagella accessory protein C (FlaC) DUF948 PF06103.11 RUS88050.1 - 0.009 16.2 3.7 0.18 12.1 0.9 2.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Filament PF00038.21 RUS88050.1 - 0.017 14.7 2.5 0.025 14.2 1.5 1.7 1 1 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 RUS88050.1 - 0.019 15.0 4.2 0.82 9.7 4.0 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 RUS88050.1 - 0.026 15.0 8.1 1.6 9.2 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DASH_Dam1 PF08653.10 RUS88050.1 - 0.027 14.3 1.7 1.8 8.4 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4611 PF15387.6 RUS88050.1 - 0.027 14.7 2.2 1.1 9.5 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4611) CREPT PF16566.5 RUS88050.1 - 0.032 14.4 5.7 1.2 9.3 1.3 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour NAGidase PF07555.13 RUS88050.1 - 0.035 13.4 0.2 0.043 13.1 0.2 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase TACC_C PF05010.14 RUS88050.1 - 0.046 13.5 2.5 0.054 13.3 0.5 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5082 PF16888.5 RUS88050.1 - 0.058 13.7 5.4 2.7 8.3 4.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4795 PF16043.5 RUS88050.1 - 0.07 12.7 6.6 0.34 10.5 6.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PspA_IM30 PF04012.12 RUS88050.1 - 0.081 12.5 2.1 0.95 9.0 0.1 2.0 1 1 0 2 2 2 0 PspA/IM30 family pPIWI_RE_REase PF18154.1 RUS88050.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE CdvA PF18822.1 RUS88050.1 - 0.13 12.1 5.4 1.1 9.1 1.2 2.5 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Cep57_MT_bd PF06657.13 RUS88050.1 - 0.15 12.6 4.8 0.58 10.6 1.9 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snf7 PF03357.21 RUS88050.1 - 0.19 11.3 6.0 0.78 9.3 1.5 2.3 1 1 0 2 2 2 0 Snf7 HMMR_N PF15905.5 RUS88050.1 - 0.19 11.1 6.4 1.7 8.1 6.5 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal YscO PF07321.12 RUS88050.1 - 0.2 11.6 2.6 6.8 6.6 0.1 2.8 1 1 2 3 3 3 0 Type III secretion protein YscO XhlA PF10779.9 RUS88050.1 - 0.2 11.9 3.2 7.9 6.8 0.1 3.2 3 0 0 3 3 3 0 Haemolysin XhlA PRKCSH_1 PF13015.6 RUS88050.1 - 0.2 11.3 2.9 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein Tnp_22_trimer PF17489.2 RUS88050.1 - 0.23 11.5 1.5 4.3 7.4 0.2 3.0 3 0 0 3 3 2 0 L1 transposable element trimerization domain NPV_P10 PF05531.12 RUS88050.1 - 0.24 11.9 9.0 10 6.7 1.1 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 RUS88050.1 - 0.24 10.7 2.6 0.43 9.9 2.7 1.4 1 1 0 1 1 1 0 FAM76 protein LPP PF04728.13 RUS88050.1 - 0.26 11.7 10.9 0.64 10.5 1.1 3.7 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FlxA PF14282.6 RUS88050.1 - 0.26 11.3 3.2 2.5 8.1 0.3 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF2802 PF10975.8 RUS88050.1 - 0.3 11.2 3.0 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Fib_alpha PF08702.10 RUS88050.1 - 0.32 11.2 6.4 1.2 9.3 4.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4600 PF15372.6 RUS88050.1 - 0.36 11.3 3.2 0.64 10.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) SKA1 PF07160.12 RUS88050.1 - 0.37 10.6 5.9 1.6 8.5 1.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 PMC2NT PF08066.12 RUS88050.1 - 0.39 11.4 4.1 3 8.6 1.4 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain SlyX PF04102.12 RUS88050.1 - 0.39 11.4 6.5 12 6.6 0.2 3.5 2 2 1 3 3 3 0 SlyX DUF4549 PF15082.6 RUS88050.1 - 0.45 10.3 3.9 0.76 9.6 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4549) DivIC PF04977.15 RUS88050.1 - 0.68 9.8 3.4 3.8 7.4 0.1 2.7 3 0 0 3 3 2 0 Septum formation initiator Cortex-I_coil PF09304.10 RUS88050.1 - 0.77 10.0 4.0 1.2 9.4 0.9 2.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil Streptin-Immun PF11083.8 RUS88050.1 - 1.3 9.5 6.0 1.8 9.0 0.3 2.9 3 1 0 3 3 3 0 Lantibiotic streptin immunity protein YabA PF06156.13 RUS88050.1 - 1.8 9.2 5.0 38 5.0 0.2 3.0 1 1 1 3 3 3 0 Initiation control protein YabA DUF2205 PF10224.9 RUS88050.1 - 2.6 8.1 8.0 11 6.2 0.3 3.0 1 1 2 3 3 3 0 Short coiled-coil protein Rootletin PF15035.6 RUS88051.1 - 2.4e-05 24.5 13.4 0.0008 19.5 7.3 2.1 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 RUS88051.1 - 0.0038 16.9 5.4 0.26 10.9 0.0 2.1 1 1 1 2 2 2 1 Intermediate filament protein Spc7 PF08317.11 RUS88051.1 - 0.0044 15.9 2.5 0.006 15.5 2.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein YabA PF06156.13 RUS88051.1 - 0.0054 17.4 4.9 0.26 11.9 3.1 2.3 1 1 1 2 2 2 1 Initiation control protein YabA CENP-H PF05837.12 RUS88051.1 - 0.011 16.2 8.9 0.34 11.3 3.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 RUS88051.1 - 0.012 15.7 7.9 1.7 8.9 0.1 2.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 MapZ_EC1 PF18041.1 RUS88051.1 - 0.1 12.8 5.3 0.13 12.5 2.1 2.2 2 0 0 2 2 2 0 MapZ extracellular domain 1 Nup54 PF13874.6 RUS88051.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ZapB PF06005.12 RUS88051.1 - 0.17 12.4 8.2 1.1 9.7 5.6 2.3 2 0 0 2 2 2 0 Cell division protein ZapB SLATT_3 PF18184.1 RUS88051.1 - 0.24 11.5 2.6 0.19 11.8 0.6 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 JIP_LZII PF16471.5 RUS88051.1 - 0.31 11.3 4.8 1.4 9.2 0.5 2.6 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 RUS88051.1 - 0.33 10.3 10.9 1.4 8.2 11.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SYCE1 PF15233.6 RUS88051.1 - 0.35 10.9 7.1 0.093 12.8 3.8 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 COG5 PF10392.9 RUS88051.1 - 0.36 11.0 8.6 0.13 12.4 2.6 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF1640 PF07798.11 RUS88051.1 - 0.42 10.6 9.0 4 7.5 9.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Lectin_N PF03954.14 RUS88051.1 - 0.51 10.1 13.6 2 8.2 0.8 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HALZ PF02183.18 RUS88051.1 - 0.51 10.6 8.2 2.2 8.5 2.8 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.8 RUS88051.1 - 0.6 10.2 15.5 11 6.0 0.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 RUS88051.1 - 0.72 10.0 3.1 4.2 7.5 0.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 RUS88051.1 - 1.1 9.2 6.8 23 5.0 0.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 RUS88051.1 - 1.9 8.7 8.8 21 5.3 0.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 RUS88051.1 - 2.2 8.6 5.7 77 3.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APC_N_CC PF16689.5 RUS88051.1 - 2.9 8.0 8.2 25 5.1 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DivIC PF04977.15 RUS88051.1 - 3.4 7.5 14.2 0.63 9.9 4.3 2.9 3 1 0 3 3 3 0 Septum formation initiator Cluap1 PF10234.9 RUS88051.1 - 4.4 6.6 10.3 3.6 6.9 5.3 2.1 1 1 0 2 2 2 0 Clusterin-associated protein-1 Spc24 PF08286.11 RUS88051.1 - 4.9 7.5 9.3 14 6.0 4.5 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 RUS88051.1 - 5 7.2 14.2 17 5.5 0.2 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 RUS88051.1 - 5.8 7.6 15.9 15 6.3 0.2 3.5 1 1 1 2 2 2 0 SlyX Cep57_CLD_2 PF14197.6 RUS88051.1 - 7.8 6.7 9.8 0.88 9.7 1.6 2.7 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 Tetraspanin PF00335.20 RUS88052.1 - 5e-40 137.6 6.4 7.1e-40 137.1 6.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3671 PF12420.8 RUS88052.1 - 0.012 15.6 0.6 0.63 10.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function Caa3_CtaG PF09678.10 RUS88052.1 - 0.22 10.9 1.9 0.36 10.3 1.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF2981 PF11200.8 RUS88052.1 - 0.61 9.8 2.9 0.23 11.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) zf-C2H2 PF00096.26 RUS88053.1 - 2.8e-40 134.5 74.2 6.1e-05 23.3 0.4 12.6 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88053.1 - 5.7e-36 120.1 79.4 0.0031 18.2 0.6 13.2 12 1 1 13 13 13 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS88053.1 - 3.3e-30 103.1 76.5 1.7e-06 28.2 0.1 12.7 13 0 0 13 13 12 9 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS88053.1 - 7.5e-26 89.6 72.4 7.1e-06 25.9 2.2 12.2 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS88053.1 - 4.1e-24 84.3 51.4 0.0003 21.0 0.1 12.5 12 0 0 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS88053.1 - 1.1e-13 51.1 59.6 0.00034 20.9 0.4 12.1 11 1 1 12 12 12 6 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS88053.1 - 2.9e-05 24.3 61.8 1.1 9.7 1.1 10.5 1 1 9 10 10 10 4 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS88053.1 - 0.012 15.7 1.8 0.012 15.7 1.8 8.9 5 5 4 10 10 9 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 RUS88053.1 - 0.053 13.4 33.8 2.4 8.2 0.0 9.6 10 0 0 10 10 9 0 zinc-finger of a C2HC-type Trm112p PF03966.16 RUS88053.1 - 0.082 13.5 13.7 8.5 7.0 0.2 4.9 3 1 0 3 3 3 0 Trm112p-like protein DUF2225 PF09986.9 RUS88053.1 - 0.09 12.5 12.4 3.4 7.3 0.5 4.7 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_11 PF16622.5 RUS88053.1 - 0.34 10.7 0.0 0.34 10.7 0.0 9.7 11 0 0 11 11 11 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 RUS88053.1 - 0.38 11.5 38.7 0.31 11.8 0.7 6.8 4 2 2 6 6 6 0 zinc-ribbon family zf_UBZ PF18439.1 RUS88053.1 - 1.1 8.9 41.3 6 6.5 0.1 9.6 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 RUS88053.1 - 2.4 8.2 24.7 1.9 8.5 0.8 5.9 6 0 0 6 6 6 0 MYM-type Zinc finger with FCS sequence motif zf-RING_7 PF02591.15 RUS88053.1 - 3.5 7.9 8.8 9.1 6.6 0.1 4.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain Macoilin PF09726.9 RUS88053.1 - 5.7 5.4 9.4 8.7 4.8 9.4 1.2 1 0 0 1 1 1 0 Macoilin family zf-C2H2_9 PF16293.5 RUS88053.1 - 9.5 6.2 27.2 0.94 9.4 0.6 7.6 6 2 3 9 9 9 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 RUS88053.1 - 9.8 5.9 15.7 0.94 9.1 0.4 4.6 4 0 0 4 4 4 0 MYST family zinc finger domain Myb_DNA-binding PF00249.31 RUS88055.1 - 1.4e-09 38.0 0.1 4.2e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 RUS88055.1 - 2.4e-06 27.2 7.9 4.4e-06 26.4 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 RUS88055.1 - 6.3e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ferrochelatase PF00762.19 RUS88056.1 - 2.8e-108 361.8 0.0 3.2e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 RUS88056.1 - 0.038 14.3 0.0 19 5.6 0.0 3.1 3 0 0 3 3 3 0 CbiX PseudoU_synth_1 PF01416.20 RUS88057.1 - 5.3e-08 33.3 0.0 1.4e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase 2-Hacid_dh_C PF02826.19 RUS88058.1 - 1.1e-55 187.7 0.0 2e-55 186.9 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS88058.1 - 1.9e-28 98.8 0.0 2.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RUS88058.1 - 0.00041 20.5 0.0 0.00071 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CLTH PF10607.9 RUS88059.1 - 2.1e-27 95.9 1.4 2.1e-27 95.9 1.4 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain EzrA PF06160.12 RUS88059.1 - 0.049 11.8 1.5 0.076 11.2 1.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-piccolo PF05715.13 RUS88059.1 - 0.064 13.4 2.1 0.16 12.2 2.1 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Laminin_II PF06009.12 RUS88059.1 - 0.095 12.7 1.8 0.2 11.7 1.8 1.5 1 0 0 1 1 1 0 Laminin Domain II HDNR PF15115.6 RUS88060.1 - 5.1e-19 69.2 0.1 5.7e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function with conserved HDNR motif Phage_ABA_S PF18066.1 RUS88061.1 - 0.02 15.6 0.5 0.029 15.0 0.4 1.4 1 1 0 1 1 1 0 Phage ABA sandwich domain NMD3 PF04981.13 RUS88061.1 - 0.03 13.8 1.4 0.04 13.4 1.4 1.2 1 0 0 1 1 1 0 NMD3 family DUF2201_N PF13203.6 RUS88061.1 - 0.71 9.4 5.1 0.76 9.3 5.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain IBN_N PF03810.19 RUS88063.1 - 1.5e-16 60.1 0.2 1.1e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.12 RUS88063.1 - 0.0022 18.1 1.9 0.85 9.7 0.0 3.1 2 1 1 3 3 3 2 Exportin 1-like protein Spt20 PF12090.8 RUS88065.1 - 0.13 11.9 7.0 0.25 10.9 7.0 1.4 1 0 0 1 1 1 0 Spt20 family Ribosomal_L34e PF01199.18 RUS88067.1 - 6.9e-17 61.5 25.9 0.76 10.1 0.2 10.5 1 1 15 16 16 16 16 Ribosomal protein L34e Ogr_Delta PF04606.12 RUS88067.1 - 2.7e-16 59.3 62.8 8.5 6.5 0.1 16.0 16 0 0 16 16 16 14 Ogr/Delta-like zinc finger SR1P PF13790.6 RUS88067.1 - 2.6e-10 40.2 58.4 25 5.1 0.1 15.4 16 0 0 16 16 16 14 SR1 protein TetR_C_5 PF08360.11 RUS88068.1 - 0.0011 19.1 15.7 20 5.4 0.4 6.1 1 1 9 10 10 10 9 QacR-like protein, C-terminal region Glycos_transf_1 PF00534.20 RUS88068.1 - 0.067 12.7 4.4 10 5.6 0.2 3.2 1 1 3 4 4 4 0 Glycosyl transferases group 1 FeoB_N PF02421.18 RUS88068.1 - 9 5.8 17.1 10 5.6 0.7 3.4 1 1 5 6 6 6 0 Ferrous iron transport protein B Laminin_G_3 PF13385.6 RUS88069.1 - 0.0019 18.4 0.3 0.0036 17.4 0.3 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Transglut_core2 PF13369.6 RUS88070.1 - 1.1e-07 31.5 0.4 7.5 6.1 0.0 6.5 1 1 6 7 7 7 4 Transglutaminase-like superfamily Nudc_N PF14050.6 RUS88070.1 - 1.3e-07 31.5 13.8 0.62 10.1 0.1 8.3 3 3 6 11 11 11 3 N-terminal conserved domain of Nudc. Forkhead PF00250.18 RUS88070.1 - 0.01 16.1 37.5 2.5 8.4 0.3 8.2 1 1 5 9 9 9 0 Forkhead domain DUF3195 PF11424.8 RUS88070.1 - 0.2 11.7 18.5 2.5 8.2 0.4 5.2 1 1 4 6 6 6 0 Protein of unknown function (DUF3195) 7TM_GPCR_Srw PF10324.9 RUS88071.1 - 0.00055 19.3 8.8 0.15 11.3 3.8 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS88071.1 - 0.011 15.0 11.9 0.21 10.9 11.9 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 RUS88073.1 - 4.5e-07 29.5 12.5 4.1e-06 26.3 12.5 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS88073.1 - 0.0018 17.6 9.0 0.027 13.7 0.9 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw MgtE_N PF03448.17 RUS88075.1 - 0.0042 17.7 0.0 0.0063 17.1 0.0 1.3 1 0 0 1 1 1 1 MgtE intracellular N domain XOO_2897-deam PF14440.6 RUS88075.1 - 0.37 10.9 7.8 31 4.8 1.3 4.2 1 1 3 4 4 4 0 Xanthomonas XOO_2897-like deaminase FAM47 PF14642.6 RUS88075.1 - 6.7 6.2 13.4 3.7 7.0 3.2 1.9 1 1 1 2 2 2 0 FAM47 family ASH PF15780.5 RUS88075.1 - 8.6 6.6 15.0 53 4.1 0.5 3.6 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Cuticle_3 PF11018.8 RUS88075.1 - 9.6 6.4 10.6 12 6.0 10.6 1.1 1 0 0 1 1 1 0 Pupal cuticle protein C1 MSSP PF03940.13 RUS88077.1 - 0.16 11.6 14.0 1.2e+03 -0.8 14.0 3.4 1 1 0 1 1 1 0 Male specific sperm protein Neuralized PF07177.12 RUS88077.1 - 0.5 10.4 5.1 3.9 7.5 0.8 2.8 1 1 1 2 2 2 0 Neuralized VWA PF00092.28 RUS88078.1 - 1.1e-42 146.3 0.6 1.3e-42 146.0 0.6 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS88078.1 - 3.4e-14 53.4 0.0 6.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 RUS88078.1 - 6.4e-09 35.9 4.7 1.4e-08 34.9 4.7 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain VWA_3 PF13768.6 RUS88078.1 - 2.4e-08 34.1 0.0 4.6e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4450 PF14614.6 RUS88078.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) CobT_C PF11775.8 RUS88078.1 - 0.13 11.9 0.0 16 5.1 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain VWA PF00092.28 RUS88080.1 - 1.4e-95 318.5 12.5 1.2e-48 165.7 0.8 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS88080.1 - 9.5e-36 122.7 2.3 1.6e-17 64.1 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.6 RUS88080.1 - 1.7e-11 44.3 0.1 0.00029 20.8 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS88080.1 - 7e-08 32.1 0.2 0.0075 15.7 0.0 4.0 3 1 1 4 4 4 2 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 RUS88080.1 - 0.012 15.7 0.2 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 vWA found in TerF C terminus DUF2201 PF09967.9 RUS88080.1 - 0.023 14.8 0.4 35 4.6 0.0 4.0 3 2 1 4 4 4 0 VWA-like domain (DUF2201) RTT107_BRCT_5 PF16770.5 RUS88080.1 - 0.046 13.6 0.0 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain Copine PF07002.16 RUS88080.1 - 0.047 13.1 0.7 3.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Copine DUF1906 PF08924.11 RUS88080.1 - 0.047 13.8 0.1 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) NAD_binding_2 PF03446.15 RUS88080.1 - 0.071 13.3 2.0 0.88 9.7 0.2 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase VWA PF00092.28 RUS88081.1 - 1.4e-15 58.0 0.1 2e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain ShK PF01549.24 RUS88081.1 - 4.2e-13 49.6 80.2 1.7e-05 25.3 9.3 9.1 10 0 0 10 10 10 5 ShK domain-like VWC PF00093.18 RUS88081.1 - 5.5e-05 23.4 36.0 0.0003 21.0 11.9 10.2 10 1 1 11 11 11 7 von Willebrand factor type C domain VWC PF00093.18 RUS88082.1 - 5.5e-09 36.2 38.7 0.00022 21.5 15.4 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain LRR_10 PF18805.1 RUS88082.1 - 0.41 10.3 4.4 8.8 6.1 0.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeat fn1 PF00039.18 RUS88082.1 - 0.55 10.5 32.2 2.8 8.2 13.8 2.7 2 0 0 2 2 2 0 Fibronectin type I domain AlbA_2 PF04326.14 RUS88083.1 - 5.6e-08 33.2 0.0 8.9e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Putative DNA-binding domain Peptidase_M15_2 PF05951.13 RUS88083.1 - 0.096 12.4 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Cpn60_TCP1 PF00118.24 RUS88085.1 - 5.1e-47 160.6 0.0 1.3e-30 106.6 0.0 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family TM2 PF05154.16 RUS88086.1 - 5e-14 52.4 9.5 5e-14 52.4 9.5 1.8 2 0 0 2 2 2 1 TM2 domain PGM_PMM_I PF02878.16 RUS88087.1 - 8.1e-14 51.5 0.0 3.6e-06 26.7 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 RUS88087.1 - 5.1e-10 39.4 0.2 1.2e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 RUS88087.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RTP1_C1 PF10363.9 RUS88089.1 - 2.9e-32 111.2 0.2 1.7e-31 108.7 0.0 2.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 RUS88089.1 - 1.1e-09 38.6 2.8 0.00012 22.4 0.3 3.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 RUS88089.1 - 4.7e-07 29.5 9.6 0.37 11.2 0.3 5.9 6 0 0 6 6 6 3 HEAT repeat RTP1_C2 PF10304.9 RUS88089.1 - 6.4e-05 22.6 0.2 0.00017 21.2 0.2 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 RUS88089.1 - 0.00044 20.7 7.0 0.35 11.4 0.1 5.3 5 0 0 5 5 5 1 HEAT-like repeat UNC45-central PF11701.8 RUS88089.1 - 0.044 13.7 0.3 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF3552 PF12072.8 RUS88091.1 - 0.00043 19.8 4.1 7.4 5.9 0.2 4.0 1 1 3 4 4 4 4 Domain of unknown function (DUF3552) BNR PF02012.20 RUS88092.1 - 0.85 9.9 4.2 31 5.1 0.3 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Ets PF00178.22 RUS88093.1 - 8.4e-36 122.3 0.1 1.2e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Ets-domain zf-RING_2 PF13639.6 RUS88095.1 - 1.8e-08 34.5 3.8 1.8e-08 34.5 3.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS88095.1 - 0.00034 20.4 3.3 0.00034 20.4 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RUS88095.1 - 0.00086 19.0 5.0 0.00086 19.0 5.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 RUS88095.1 - 0.0026 17.9 5.8 0.15 12.3 2.4 2.6 2 0 0 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RUS88095.1 - 0.0049 16.5 2.9 0.0049 16.5 2.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 RUS88095.1 - 0.0099 15.9 4.6 0.0099 15.9 4.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RUS88095.1 - 0.011 16.0 4.0 0.011 16.0 4.0 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain RNF220 PF15926.5 RUS88095.1 - 0.019 14.6 1.3 0.039 13.6 1.3 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_3 PF13920.6 RUS88095.1 - 0.02 14.8 10.5 0.095 12.6 2.2 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS88095.1 - 0.033 14.1 3.5 0.033 14.1 3.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 RUS88095.1 - 0.043 14.1 2.4 0.043 14.1 2.4 2.3 2 0 0 2 2 2 0 RING-like domain zf-RING_5 PF14634.6 RUS88095.1 - 0.061 13.3 9.9 0.2 11.7 2.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 RUS88095.1 - 0.31 10.9 6.9 4.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Vps39_2 PF10367.9 RUS88095.1 - 0.39 11.2 3.3 2.9 8.4 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.6 RUS88095.1 - 0.77 9.7 12.5 1.1 9.3 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 RUS88095.1 - 0.8 10.0 6.8 0.11 12.8 1.8 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Acyl_transf_1 PF00698.21 RUS88096.1 - 8.8e-18 64.9 0.2 1.7e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain MCM PF00493.23 RUS88097.1 - 5.5e-99 329.8 0.0 7.9e-99 329.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RUS88097.1 - 4e-39 133.3 0.9 7.3e-39 132.5 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS88097.1 - 1.3e-25 89.6 0.2 3.1e-25 88.4 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RUS88097.1 - 1.5e-18 67.3 0.2 5.5e-18 65.5 0.2 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RUS88097.1 - 1.3e-08 34.5 0.0 1.1e-05 24.9 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS88097.1 - 2.4e-08 34.1 0.0 1.2e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RUS88097.1 - 4.8e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS88097.1 - 0.0021 17.8 0.2 4.2 7.0 0.0 3.1 4 0 0 4 4 4 2 Sigma-54 interaction domain Elf1 PF05129.13 RUS88097.1 - 0.023 14.7 2.4 0.082 13.0 2.4 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA PF00004.29 RUS88097.1 - 0.031 14.7 0.0 0.097 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS88097.1 - 0.064 13.5 0.2 1.6 9.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain TIP49_C PF17856.1 RUS88097.1 - 0.094 12.9 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_16 PF13191.6 RUS88097.1 - 0.2 12.0 0.5 2.3 8.6 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Voltage_CLC PF00654.20 RUS88098.1 - 3.9e-62 210.6 21.9 2.8e-50 171.6 9.1 2.4 3 0 0 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 RUS88098.1 - 3.7e-10 40.1 0.0 1.5e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain DUF1104 PF06518.11 RUS88098.1 - 0.23 11.9 1.5 26 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) LapA_dom PF06305.11 RUS88098.1 - 2.2 8.2 7.5 0.48 10.3 0.1 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Neurensin PF14927.6 RUS88098.1 - 4.2 7.1 5.6 0.43 10.3 0.1 2.3 3 0 0 3 3 3 0 Neurensin CTD PF12815.7 RUS88099.1 - 9.3e-05 22.9 7.6 0.002 18.7 7.6 2.6 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Tli4_C PF18426.1 RUS88099.1 - 0.0058 17.0 0.3 1.6 9.0 0.1 2.3 1 1 1 2 2 2 2 Tle cognate immunity protein 4 C-terminal domain ATF7IP_BD PF16788.5 RUS88099.1 - 0.21 11.7 10.3 3.4 7.7 10.3 2.1 1 1 0 1 1 1 0 ATF-interacting protein binding domain RR_TM4-6 PF06459.12 RUS88101.1 - 0.3 10.9 1.2 0.59 9.9 1.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ig_Tie2_1 PF10430.9 RUS88101.1 - 0.31 11.5 0.0 0.31 11.5 0.0 3.0 4 0 0 4 4 4 0 Tie-2 Ig-like domain 1 EPTP PF03736.17 RUS88103.1 - 0.00016 21.6 0.0 1.6e+02 2.4 0.0 6.5 1 1 9 10 10 10 0 EPTP domain BDV_G PF06208.11 RUS88103.1 - 0.0024 17.1 0.1 4.7 6.3 0.0 3.3 1 1 3 4 4 4 3 Borna disease virus G protein Gln-synt_N_2 PF16952.5 RUS88103.1 - 0.072 12.9 1.3 99 2.8 0.1 4.3 1 1 4 6 6 6 0 Glutamine synthetase N-terminal domain FAM92 PF06730.11 RUS88104.1 - 6.4e-51 172.9 5.3 8.7e-51 172.5 5.3 1.1 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.18 RUS88104.1 - 1.2e-06 28.4 5.6 1.6e-06 28.0 5.6 1.2 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RUS88104.1 - 1e-05 25.4 6.9 1.4e-05 25.0 6.9 1.1 1 0 0 1 1 1 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 RUS88104.1 - 0.00064 19.2 3.9 0.002 17.6 3.9 1.7 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein CtIP_N PF10482.9 RUS88104.1 - 0.035 14.1 1.6 0.07 13.2 1.6 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Vps5 PF09325.10 RUS88104.1 - 0.039 13.5 7.0 0.38 10.3 7.0 2.2 1 1 0 1 1 1 0 Vps5 C terminal like DUF3136 PF11334.8 RUS88104.1 - 0.049 13.4 0.4 0.96 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) WD-3 PF09765.9 RUS88104.1 - 0.1 11.9 3.7 0.31 10.4 0.7 2.1 1 1 1 2 2 2 0 WD-repeat region NOA36 PF06524.12 RUS88104.1 - 0.32 10.3 4.8 0.59 9.4 4.8 1.5 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 RUS88105.1 - 2.9e-06 27.0 0.1 9e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 RUS88105.1 - 0.054 13.3 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) dNK PF01712.19 RUS88106.1 - 4.1e-30 105.2 0.1 5.9e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 RUS88106.1 - 0.0021 18.3 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 RUS88106.1 - 0.0051 16.8 0.0 0.0065 16.5 0.0 1.4 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CoaE PF01121.20 RUS88106.1 - 0.0057 16.3 0.1 0.022 14.4 0.0 2.0 3 0 0 3 3 3 1 Dephospho-CoA kinase AAA_16 PF13191.6 RUS88106.1 - 0.02 15.3 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 RUS88106.1 - 0.031 14.8 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 RUS88106.1 - 0.032 14.5 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 RUS88106.1 - 0.035 13.3 0.0 0.15 11.2 0.0 1.9 1 1 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 RUS88106.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 RUS88106.1 - 0.058 13.9 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 RUS88106.1 - 0.079 12.2 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 RUS88106.1 - 0.09 13.3 0.2 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RUS88106.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 RUS88106.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RabGGT_insert PF07711.11 RUS88107.1 - 0.00091 19.7 1.2 0.29 11.6 0.1 2.5 1 1 0 2 2 2 2 Rab geranylgeranyl transferase alpha-subunit, insert domain Arabino_trans_N PF17689.1 RUS88107.1 - 0.023 14.9 10.0 0.19 11.8 4.4 2.1 1 1 1 2 2 2 0 Arabinosyltransferase concanavalin like domain Gp5_C PF06715.12 RUS88107.1 - 0.36 11.1 1.8 5.7 7.3 0.1 3.2 2 2 1 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF2345 PF10106.9 RUS88107.1 - 0.71 9.7 18.7 2.4 8.0 18.9 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF1381 PF07129.11 RUS88107.1 - 9 6.2 13.1 20 5.1 0.4 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1381) tRNA-synt_1 PF00133.22 RUS88108.1 - 2e-45 155.2 1.4 1.8e-22 79.3 0.5 5.0 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RUS88108.1 - 2e-29 102.6 0.0 3.2e-21 75.6 0.0 3.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 RUS88108.1 - 0.0042 16.5 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 RUS88108.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Lar_restr_allev PF14354.6 RUS88108.1 - 0.13 12.6 0.6 26 5.3 0.0 2.8 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 RUS88108.1 - 0.21 11.0 2.8 12 5.4 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 RUS88108.1 - 0.33 11.1 1.8 1.8 8.8 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 RUS88108.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Double zinc ribbon DUF3446 PF11928.8 RUS88108.1 - 2.1 8.7 13.8 0.55 10.6 10.3 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 RUS88108.1 - 6.7 6.2 24.9 12 5.4 24.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNARE PF05739.19 RUS88109.1 - 6.2e-19 67.7 2.7 6.2e-19 67.7 2.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 RUS88109.1 - 6.1e-07 29.3 10.8 1.2e-06 28.3 10.8 1.4 1 0 0 1 1 1 1 Syntaxin GCP_C_terminal PF04130.13 RUS88109.1 - 0.0078 15.7 3.6 0.0078 15.7 3.6 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal MCPsignal PF00015.21 RUS88109.1 - 0.12 12.1 5.4 0.43 10.4 0.2 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RNA_bind PF08675.11 RUS88109.1 - 0.14 12.2 0.1 21 5.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain Orf78 PF06024.12 RUS88109.1 - 0.48 10.8 3.4 0.23 11.8 0.6 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF5345 PF17280.2 RUS88109.1 - 0.75 9.8 4.5 0.17 11.9 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3675 PF12428.8 RUS88109.1 - 0.92 10.1 4.1 0.78 10.3 0.2 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3675) DUF2116 PF09889.9 RUS88109.1 - 1.6 8.8 8.9 0.31 11.0 4.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Syntaxin_2 PF14523.6 RUS88109.1 - 1.8 9.0 15.8 0.24 11.8 9.5 2.3 2 1 0 2 2 2 0 Syntaxin-like protein Ras PF00071.22 RUS88110.1 - 5e-58 195.3 0.1 6.2e-58 195.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS88110.1 - 1.9e-35 121.7 0.0 3.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS88110.1 - 8.2e-14 51.4 0.0 9.8e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS88110.1 - 9.8e-06 25.6 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS88110.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS88110.1 - 3.4e-05 23.8 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 RUS88110.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 RUS88110.1 - 0.00027 20.4 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 RUS88110.1 - 0.0039 17.6 0.2 0.011 16.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 RUS88110.1 - 0.0049 16.3 0.1 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 RUS88110.1 - 0.033 14.7 0.2 0.17 12.4 0.2 2.1 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 RUS88110.1 - 0.033 14.5 0.1 1.3 9.3 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS88110.1 - 0.033 13.9 0.2 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 RUS88110.1 - 0.073 12.2 0.3 3.2 6.8 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 RUS88110.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RUS88110.1 - 0.16 12.3 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 RUS88110.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 RUS88110.1 - 0.18 11.5 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain P66_CC PF16563.5 RUS88111.1 - 3.8e-13 48.8 0.4 3.8e-13 48.8 0.4 3.2 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 RUS88111.1 - 1.1e-05 24.9 0.8 2.1e-05 24.0 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger GXWXG PF14231.6 RUS88112.1 - 0.0015 18.6 27.1 5 7.3 0.1 7.0 1 1 5 7 7 7 7 GXWXG protein HECT PF00632.25 RUS88113.1 - 8.6e-83 278.3 0.2 1.3e-56 192.4 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.26 RUS88113.1 - 5.9e-46 154.2 22.1 1.3e-13 50.8 1.8 5.2 5 0 0 5 5 5 4 WW domain Peptidase_A22B PF04258.13 RUS88114.1 - 5.5e-92 308.3 16.3 7.5e-92 307.9 16.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase CHCH PF06747.13 RUS88115.1 - 8.4e-06 25.8 5.6 1.2e-05 25.3 5.6 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 RUS88115.1 - 0.00037 20.6 6.3 0.00043 20.4 6.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TPR_2 PF07719.17 RUS88116.1 - 1.8e-08 33.9 1.7 0.014 15.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 RUS88116.1 - 8.7e-08 32.4 0.1 1.7e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.6 RUS88116.1 - 0.00047 19.8 1.5 0.62 9.8 0.7 2.8 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 RUS88116.1 - 0.0017 18.8 0.7 1.1 9.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS88116.1 - 0.002 18.8 0.6 8.5 7.5 0.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RUS88116.1 - 0.0038 17.0 0.2 5 7.1 0.7 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS88116.1 - 0.026 14.9 0.4 17 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS88116.1 - 0.053 14.2 6.1 3.1 8.5 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 RUS88116.1 - 1.9 8.6 8.6 1.2 9.1 1.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lectin_C PF00059.21 RUS88117.1 - 5.1e-11 43.3 0.0 7.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS88118.1 - 2.1e-11 44.5 0.0 2.3e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain Glu-tRNAGln PF02686.15 RUS88119.1 - 2.3e-11 43.8 0.2 6.7e-11 42.3 0.1 1.7 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit EF-hand_7 PF13499.6 RUS88120.1 - 9.2e-07 29.2 17.7 0.18 12.2 7.4 6.0 4 2 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS88120.1 - 0.0058 16.5 8.4 1.5 8.7 0.3 5.0 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS88120.1 - 0.0066 15.9 0.0 0.0066 15.9 0.0 5.2 6 0 0 6 6 6 1 EF hand EF-hand_6 PF13405.6 RUS88120.1 - 0.021 14.7 26.4 0.95 9.6 0.0 7.6 6 2 2 8 8 8 0 EF-hand domain EF-hand_1 PF00036.32 RUS88120.1 - 0.096 12.3 0.0 0.096 12.3 0.0 6.9 6 1 1 7 7 7 0 EF hand Dockerin_1 PF00404.18 RUS88120.1 - 3.1 8.1 7.6 15 5.8 1.3 4.0 2 1 1 3 3 3 0 Dockerin type I domain Fibrinogen_C PF00147.18 RUS88121.1 - 4.3e-13 49.6 0.0 5.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain AAA_lid_11 PF18198.1 RUS88121.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain DUF3471 PF11954.8 RUS88121.1 - 0.14 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) FoP_duplication PF13865.6 RUS88122.1 - 4.2e-16 59.2 13.6 4.2e-16 59.2 13.6 5.4 1 1 4 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 Med30 PF11315.8 RUS88124.1 - 0.0086 16.3 8.7 0.0086 16.3 8.7 2.8 3 0 0 3 3 3 1 Mediator complex subunit 30 DUF948 PF06103.11 RUS88124.1 - 3.1 8.1 10.7 2.2 8.6 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-H2C2_2 PF13465.6 RUS88126.1 - 8.4e-27 92.4 43.3 3.3e-08 33.6 0.5 6.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS88126.1 - 1.3e-23 82.0 43.6 8.6e-07 29.1 3.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88126.1 - 1.2e-14 53.7 39.9 0.00095 19.8 2.5 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 RUS88126.1 - 1.4e-07 31.6 28.2 0.27 11.7 2.9 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS88126.1 - 6e-05 22.7 28.8 0.0067 16.2 0.3 5.4 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS88126.1 - 7.4e-05 22.9 20.6 1.2 9.5 1.1 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS88126.1 - 0.0025 17.7 1.0 0.0025 17.7 1.0 5.9 5 1 0 5 5 5 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 RUS88126.1 - 0.04 14.0 21.5 0.65 10.2 3.6 4.6 3 2 1 4 4 4 0 Zinc ribbon domain Zf_RING PF16744.5 RUS88126.1 - 0.13 12.4 14.6 2.4 8.3 0.0 4.6 2 1 1 4 4 4 0 KIAA1045 RING finger Baculo_IE-1 PF05290.11 RUS88126.1 - 0.13 12.2 3.1 44 4.0 0.1 3.7 2 1 1 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-BED PF02892.15 RUS88126.1 - 0.18 11.9 22.7 5.9 7.0 8.0 5.1 2 1 2 4 4 4 0 BED zinc finger BolA PF01722.18 RUS88126.1 - 0.19 12.0 5.2 6.1 7.2 0.3 3.3 2 1 1 3 3 3 0 BolA-like protein zf-MYST PF17772.1 RUS88126.1 - 0.69 9.6 10.2 18 5.0 0.1 4.7 4 1 1 5 5 5 0 MYST family zinc finger domain zf_UBZ PF18439.1 RUS88126.1 - 2.3 7.9 16.9 13 5.5 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-UBR PF02207.20 RUS88126.1 - 3.1 8.0 24.1 9.2 6.5 9.7 3.5 1 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF3268 PF11672.8 RUS88126.1 - 3.8 7.8 10.1 7.1 7.0 1.0 2.9 3 0 0 3 3 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 RUS88126.1 - 4.8 8.0 14.3 7 7.5 1.3 3.4 1 1 1 3 3 3 0 zinc-ribbon family FYVE PF01363.21 RUS88126.1 - 7 6.9 20.3 6.7 6.9 6.6 3.3 1 1 1 2 2 2 0 FYVE zinc finger RRM_1 PF00076.22 RUS88128.1 - 7.1e-19 67.4 0.2 2.6e-12 46.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 RUS88128.1 - 0.00057 20.2 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 RUS88128.1 - 0.064 13.3 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UBA_6 PF18039.1 RUS88129.1 - 4.5e-10 39.3 0.1 1.6 8.7 0.0 5.9 1 1 4 5 5 5 4 UBA-like domain CagY_M PF07337.11 RUS88129.1 - 5.7e-07 29.0 5.9 23 4.7 0.1 7.8 2 2 3 5 5 5 0 DC-EC Repeat Collagen_mid PF15984.5 RUS88129.1 - 0.0021 17.9 0.0 0.051 13.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial collagen, middle region Octopine_DH PF02317.17 RUS88129.1 - 0.0029 17.7 0.1 1.7 8.7 0.1 2.9 1 1 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain RXLR_WY PF18634.1 RUS88129.1 - 0.003 17.4 0.0 15 5.6 0.0 4.2 2 1 4 6 6 6 0 RXLR phytopathogen effector protein WY-domain Exo70 PF03081.15 RUS88129.1 - 0.0033 16.5 0.2 0.12 11.3 0.1 2.0 1 1 1 2 2 2 2 Exo70 exocyst complex subunit Tti2 PF10521.9 RUS88129.1 - 0.013 15.1 1.6 7.7 6.0 0.2 3.3 1 1 3 4 4 4 0 Tti2 family Baculo_PEP_C PF04513.12 RUS88129.1 - 0.014 15.4 0.0 0.073 13.1 0.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF294 PF03445.13 RUS88129.1 - 0.22 11.3 9.7 18 5.1 0.7 3.4 1 1 2 3 3 3 0 Putative nucleotidyltransferase DUF294 DUF2100 PF09873.9 RUS88129.1 - 0.24 11.2 0.3 2.3 8.0 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2100) DUF3677 PF12432.8 RUS88129.1 - 0.36 11.2 6.0 5.1 7.5 6.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3677) IL32 PF15225.6 RUS88129.1 - 1.2 9.6 5.9 8.4 6.8 2.4 2.0 1 1 1 2 2 2 0 Interleukin 32 CLASP_N PF12348.8 RUS88129.1 - 3.2 7.3 5.6 4.2 6.9 3.6 1.8 1 1 1 2 2 2 0 CLASP N terminal Staphostatin_B PF09023.10 RUS88130.1 - 0.0067 16.4 3.4 3.6 7.7 0.1 3.6 1 1 3 4 4 4 1 Staphostatin B DUF2656 PF10847.8 RUS88130.1 - 0.0073 16.4 0.0 23 5.1 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2656) DUF1202 PF06717.11 RUS88130.1 - 0.11 11.9 1.3 2.5 7.4 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1202) DUF4361 PF14274.6 RUS88130.1 - 0.2 11.9 0.0 0.96 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) GCR PF02155.15 RUS88130.1 - 2.5 7.0 12.6 18 4.2 0.2 4.5 3 1 2 5 5 5 0 Glucocorticoid receptor KCNQ2_u3 PF16642.5 RUS88130.1 - 5.4 8.1 6.1 86 4.2 0.1 3.3 2 2 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PI3K_1B_p101 PF10486.9 RUS88133.1 - 0.038 11.8 1.4 0.056 11.2 1.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AAA_7 PF12775.7 RUS88133.1 - 0.087 12.3 0.0 0.86 9.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Ank_2 PF12796.7 RUS88134.1 - 3.1e-06 27.7 0.5 2.4e-05 24.9 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS88134.1 - 1.1e-05 25.8 0.3 0.007 16.9 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88134.1 - 0.00023 21.3 0.6 7.5 7.5 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeat Ank PF00023.30 RUS88134.1 - 0.00076 19.8 1.5 1 9.9 0.0 4.4 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 RUS88134.1 - 0.0032 17.7 0.1 0.073 13.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_1 PF00515.28 RUS88135.1 - 4.9e-10 38.8 17.9 0.025 14.4 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 RUS88135.1 - 3.4e-09 36.1 16.8 0.076 13.2 0.2 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 RUS88135.1 - 3.2e-06 27.3 10.5 0.0027 18.0 0.2 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS88135.1 - 4.4e-05 24.0 2.8 0.25 12.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS88135.1 - 0.0011 19.0 8.6 0.0025 17.9 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS88135.1 - 0.0099 16.2 2.0 1 9.9 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS88135.1 - 0.014 16.0 5.1 5 8.0 0.6 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS88135.1 - 0.022 14.8 6.8 4 7.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS88135.1 - 0.022 15.0 10.5 0.035 14.3 1.7 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NYD-SP12_N PF15015.6 RUS88135.1 - 0.042 12.2 0.1 0.062 11.7 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal MIT PF04212.18 RUS88135.1 - 0.05 13.7 6.8 0.91 9.6 0.2 3.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 RUS88135.1 - 0.17 12.8 1.2 94 4.2 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS88135.1 - 0.56 10.7 2.6 62 4.2 0.3 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS88135.1 - 1.8 8.3 4.0 9.2 6.0 0.4 3.4 4 0 0 4 4 4 0 TPR repeat SVA PF05326.11 RUS88136.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) Cpn60_TCP1 PF00118.24 RUS88137.1 - 1.7e-156 521.7 14.3 1.9e-156 521.5 14.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gln-synt_C PF00120.24 RUS88138.1 - 5.9e-68 229.4 0.0 1e-67 228.6 0.0 1.3 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain TFIIS_M PF07500.14 RUS88140.1 - 6.5e-30 103.9 0.8 6.5e-30 103.9 0.8 3.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 RUS88140.1 - 1.9e-29 102.5 0.0 4.1e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 SPOC domain BRK PF07533.16 RUS88140.1 - 2.8e-13 49.3 0.0 5.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 BRK domain PHD PF00628.29 RUS88140.1 - 6.7e-10 38.7 10.8 2e-09 37.2 10.8 1.9 1 0 0 1 1 1 1 PHD-finger HTH_psq PF05225.16 RUS88142.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 RUS88142.1 - 0.028 14.5 0.5 0.05 13.6 0.5 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 RUS88142.1 - 0.04 14.5 0.0 16 6.2 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 RUS88142.1 - 0.067 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Transposase RCC1 PF00415.18 RUS88143.1 - 2.7e-78 258.4 19.4 4.6e-14 52.8 0.3 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS88143.1 - 4.3e-35 118.8 40.6 7.6e-07 28.8 2.5 8.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat PH_18 PF18469.1 RUS88143.1 - 0.15 12.1 0.2 0.65 10.0 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4766 PF15973.5 RUS88143.1 - 5.1 7.7 14.0 0.2 12.2 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4766) Thioesterase PF00975.20 RUS88145.1 - 5.5e-38 131.4 0.0 6.2e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 RUS88145.1 - 4.1e-06 27.5 0.0 4.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RUS88145.1 - 1.5e-05 24.7 0.0 3.1e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 RUS88145.1 - 0.051 13.4 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 RUS88145.1 - 0.062 12.6 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 RUS88145.1 - 0.076 12.6 0.0 0.38 10.3 0.0 1.9 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase IMS PF00817.20 RUS88146.1 - 5.4e-44 149.8 0.0 1.2e-43 148.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RUS88146.1 - 3.7e-15 56.6 0.0 1.1e-14 55.2 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.8 RUS88146.1 - 0.0022 18.2 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 Pathogenicity locus FliG_M PF14841.6 RUS88146.1 - 0.012 15.9 0.2 0.19 11.9 0.0 2.7 2 0 0 2 2 2 0 FliG middle domain UBM PF14377.6 RUS88146.1 - 0.014 14.8 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin binding region MgtE_N PF03448.17 RUS88146.1 - 0.022 15.3 0.1 1.5 9.5 0.0 2.6 2 0 0 2 2 2 0 MgtE intracellular N domain DUF4332 PF14229.6 RUS88146.1 - 0.031 14.5 0.1 0.13 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HHH_5 PF14520.6 RUS88146.1 - 0.036 14.7 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HU-CCDC81_bac_2 PF18175.1 RUS88146.1 - 0.1 12.4 0.2 13 5.7 0.1 2.8 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 HLH PF00010.26 RUS88147.1 - 1.7e-18 66.3 1.6 2.5e-18 65.8 1.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5107 PF17128.4 RUS88147.1 - 0.059 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) TPH PF13868.6 RUS88148.1 - 2.4e-22 78.9 138.2 2.4e-22 78.9 138.2 2.4 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain ABC_membrane PF00664.23 RUS88149.1 - 2.2e-51 175.1 34.2 1.3e-30 107.0 17.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS88149.1 - 7.3e-49 165.8 0.4 9.6e-27 94.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RUS88149.1 - 2.4e-10 40.3 4.6 0.0019 17.7 0.1 4.6 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS88149.1 - 9.6e-07 28.9 0.3 0.017 15.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS88149.1 - 5.5e-06 26.9 1.9 0.14 12.6 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RUS88149.1 - 1.1e-05 25.1 0.9 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS88149.1 - 1.7e-05 24.8 0.7 0.055 13.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 RUS88149.1 - 2.7e-05 23.6 0.6 0.01 15.2 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 RUS88149.1 - 3.7e-05 23.3 0.1 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 RUS88149.1 - 7.8e-05 22.8 3.3 0.11 12.5 0.5 2.9 3 0 0 3 3 2 2 Dynamin family AAA_21 PF13304.6 RUS88149.1 - 0.00016 21.6 3.1 0.64 9.8 0.1 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 RUS88149.1 - 0.00024 21.4 0.6 1.6 9.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 RUS88149.1 - 0.00027 20.2 0.1 0.022 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 RUS88149.1 - 0.00081 19.6 7.3 0.18 11.9 0.2 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain T2SSE PF00437.20 RUS88149.1 - 0.0033 16.5 0.7 0.96 8.5 0.1 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein MeaB PF03308.16 RUS88149.1 - 0.012 14.6 0.1 0.48 9.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 RUS88149.1 - 0.014 15.1 0.9 12 5.6 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 RUS88149.1 - 0.054 12.4 0.4 6.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 RUS88149.1 - 0.07 12.9 0.4 14 5.4 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase IIGP PF05049.13 RUS88149.1 - 0.072 12.1 0.1 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 RUS88149.1 - 0.092 12.3 0.6 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 RUS88149.1 - 0.11 12.7 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS88149.1 - 0.14 12.1 1.7 8 6.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.6 RUS88149.1 - 0.17 11.6 0.4 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 RUS88151.1 - 1e-24 87.1 11.6 1.3e-24 86.8 11.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS88151.1 - 9.3e-07 28.0 5.9 1.1e-06 27.8 5.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RUS88151.1 - 0.00016 21.1 2.0 0.00024 20.6 2.0 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 RUS88151.1 - 0.0008 18.1 2.1 0.0008 18.1 2.1 1.4 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RUS88152.1 - 1.4e-17 63.6 8.6 2.5e-15 56.3 3.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 RUS88153.1 - 7.1e-54 182.9 0.8 1.2e-53 182.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88153.1 - 4.9e-29 101.4 0.0 1e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase YabA PF06156.13 RUS88153.1 - 9.1 7.0 15.8 0.89 10.2 2.8 3.4 3 1 0 3 3 3 0 Initiation control protein YabA zf-UBP PF02148.19 RUS88154.1 - 0.077 13.3 6.0 0.2 12.0 6.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF4573 PF15140.6 RUS88155.1 - 4.3e-11 42.9 7.1 0.0011 18.8 0.2 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF4573) Plasmodium_HRP PF05403.11 RUS88155.1 - 1.3e-07 31.7 9.6 9.5e-07 28.8 9.6 2.0 1 1 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) DUF4170 PF13773.6 RUS88155.1 - 0.43 10.8 45.9 24 5.2 0.6 11.5 2 2 11 13 13 13 0 Domain of unknown function (DUF4170) DUF2369 PF10179.9 RUS88155.1 - 4.2 7.8 15.8 54 4.3 2.1 4.7 1 1 5 6 6 6 0 Uncharacterised conserved protein (DUF2369) CbiQ PF02361.16 RUS88155.1 - 8.5 5.9 28.0 2.5e+03 -2.1 0.0 7.4 2 1 0 2 2 2 0 Cobalt transport protein Retrotran_gag_3 PF14244.6 RUS88156.1 - 1.9e-08 34.0 22.6 54 3.7 0.1 14.2 1 1 19 20 20 20 1 gag-polypeptide of LTR copia-type Tcp10_C PF07202.13 RUS88156.1 - 1.4e-05 25.1 0.0 0.026 14.5 0.0 3.0 1 1 1 2 2 2 2 T-complex protein 10 C-terminus Paramecium_SA PF01508.16 RUS88156.1 - 0.073 13.5 12.3 1.5e+04 -3.5 12.3 5.1 1 1 0 1 1 1 0 Paramecium surface antigen domain Bap31 PF05529.12 RUS88157.1 - 6.4 6.6 6.9 0.52 10.2 1.6 1.9 2 1 0 2 2 2 0 Bap31/Bap29 transmembrane region MFS_1 PF07690.16 RUS88158.1 - 8.8e-05 21.6 0.2 9.2e-05 21.5 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 RUS88158.1 - 0.0046 15.6 0.9 0.0059 15.3 0.9 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like CCDC85 PF10226.9 RUS88159.1 - 7e-65 218.3 0.3 1.5e-64 217.3 0.3 1.5 1 0 0 1 1 1 1 CCDC85 family DUF5082 PF16888.5 RUS88159.1 - 0.021 15.1 0.5 3.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 RUS88159.1 - 1.7 8.8 8.7 18 5.5 1.7 3.2 3 0 0 3 3 3 0 bZIP transcription factor Shugoshin_N PF07558.11 RUS88159.1 - 2.9 7.8 7.6 0.27 11.1 1.3 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Rabaptin PF03528.15 RUS88159.1 - 4.3 5.9 7.3 10 4.7 0.6 2.2 1 1 1 2 2 2 0 Rabaptin Methyltransf_23 PF13489.6 RUS88160.1 - 5.7e-15 55.5 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS88160.1 - 6.7e-15 55.5 0.0 1.5e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS88160.1 - 4.6e-12 46.5 0.0 1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS88160.1 - 1.4e-08 35.4 0.1 5.6e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS88160.1 - 2.8e-07 30.5 0.0 7.8e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_7 PF03492.15 RUS88160.1 - 0.0044 16.3 0.2 0.047 12.9 0.1 2.1 2 0 0 2 2 2 1 SAM dependent carboxyl methyltransferase Ubie_methyltran PF01209.18 RUS88160.1 - 0.0055 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 RUS88160.1 - 0.026 14.4 0.0 0.085 12.7 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 RUS88160.1 - 0.053 13.1 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Spectrin PF00435.21 RUS88160.1 - 0.13 12.8 1.6 0.26 11.8 1.6 1.4 1 0 0 1 1 1 0 Spectrin repeat Ald_Xan_dh_C2 PF02738.18 RUS88161.1 - 1.1e-61 208.9 0.6 1.5e-45 155.7 0.2 2.3 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 RUS88161.1 - 1.1e-50 171.8 0.0 1.9e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 RUS88161.1 - 5.8e-29 100.7 0.1 1.2e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 RUS88161.1 - 6.5e-29 99.8 0.0 1.6e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 RUS88161.1 - 1e-28 99.5 0.0 2.1e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 RUS88161.1 - 1.4e-07 31.3 2.2 4e-07 29.9 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain L_biotic_typeA PF04604.13 RUS88161.1 - 0.093 12.6 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Type-A lantibiotic Ald_Xan_dh_C2 PF02738.18 RUS88162.1 - 2.5e-24 85.7 0.0 2.6e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Pkinase PF00069.25 RUS88163.1 - 5.7e-58 196.4 0.0 7.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88163.1 - 2.7e-34 118.6 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS88163.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS88163.1 - 0.00034 19.7 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RUS88163.1 - 0.0039 16.6 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SelP_N PF04592.14 RUS88163.1 - 0.014 14.8 14.9 0.025 14.0 14.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 RUS88163.1 - 0.51 9.5 4.8 0.7 9.0 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CAF20 PF17052.5 RUS88163.1 - 0.62 10.2 4.1 1 9.5 4.1 1.3 1 0 0 1 1 1 0 Cap associated factor zf-C2H2 PF00096.26 RUS88164.1 - 5.3e-08 32.9 41.0 0.002 18.5 0.8 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88164.1 - 1.7e-07 31.5 46.4 0.007 17.1 1.4 6.3 6 0 0 6 6 5 4 C2H2-type zinc finger MSP1_C PF07462.11 RUS88164.1 - 0.0045 15.8 0.7 0.0075 15.0 0.7 1.3 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus HP_OMP PF01856.17 RUS88164.1 - 0.012 15.6 0.3 0.022 14.8 0.3 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein zf-met PF12874.7 RUS88164.1 - 0.013 15.9 22.4 0.12 12.8 0.2 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type ARS2 PF04959.13 RUS88164.1 - 0.22 11.9 5.2 0.3 11.5 1.9 2.8 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 RUS88164.1 - 0.33 11.6 15.1 0.13 12.9 6.9 3.5 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 RUS88164.1 - 0.9 10.1 31.9 1.3 9.6 0.2 6.2 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS88164.1 - 1.3 9.1 33.6 0.24 11.4 0.3 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS88164.1 - 2.4 8.5 31.2 15 6.0 4.8 5.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF4379 PF14311.6 RUS88164.1 - 7.5 7.0 9.9 0.58 10.6 0.3 3.3 3 0 0 3 3 3 0 Probable Zinc-ribbon domain Str_synth PF03088.16 RUS88166.1 - 3.5e-24 84.7 0.0 9.7e-24 83.3 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 RUS88166.1 - 4.3e-15 56.0 0.0 1e-14 54.7 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 RUS88166.1 - 0.00029 21.2 0.9 0.044 14.3 0.1 3.5 4 0 0 4 4 4 1 PQQ-like domain Arylesterase PF01731.20 RUS88166.1 - 0.018 15.2 0.0 0.12 12.6 0.0 2.5 2 1 0 2 2 2 0 Arylesterase Peptidase_S9_N PF02897.15 RUS88166.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Ephrin_rec_like PF07699.13 RUS88166.1 - 0.45 10.3 2.1 0.8 9.5 2.1 1.4 1 0 0 1 1 1 0 Putative ephrin-receptor like TFB6 PF17110.5 RUS88167.1 - 4.6 6.9 7.6 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Csm2_III-A PF03750.13 RUS88168.1 - 0.12 13.3 1.9 0.2 12.5 0.4 2.2 2 0 0 2 2 2 0 Csm2 Type III-A DHC_N2 PF08393.13 RUS88169.1 - 3.4e-119 398.5 0.3 5.2e-119 397.9 0.3 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RUS88169.1 - 2.8e-37 128.4 0.5 5.2e-37 127.5 0.5 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 RUS88169.1 - 0.012 16.0 0.1 0.012 16.0 0.1 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS88169.1 - 0.019 15.0 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS88169.1 - 0.14 12.5 0.4 1.1 9.6 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 RUS88169.1 - 0.15 12.6 2.0 1.6 9.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 RUS88169.1 - 0.18 11.5 1.0 0.52 10.0 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 RUS88170.1 - 1.1e-107 359.9 0.0 1.5e-107 359.4 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RUS88170.1 - 0.00044 20.3 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RUS88170.1 - 0.022 14.3 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 RUS88170.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 RUS88171.1 - 2.2e-37 128.3 0.2 1.4e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RUS88171.1 - 9.5e-15 54.8 0.0 2e-10 40.9 0.0 3.0 2 1 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RUS88171.1 - 1.3e-07 32.1 0.1 3.9e-07 30.6 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RUS88171.1 - 0.00026 21.3 0.3 0.0024 18.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS88171.1 - 0.00096 19.2 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 RUS88171.1 - 0.0035 17.7 0.2 0.0079 16.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RUS88171.1 - 0.0038 17.8 1.7 0.0048 17.4 0.5 1.7 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 RUS88171.1 - 0.012 15.3 0.3 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 RUS88171.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 RUS88171.1 - 0.055 12.9 0.1 0.54 9.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 RUS88171.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 RUS88171.1 - 0.078 13.4 0.3 0.25 11.7 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RUS88171.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RUS88171.1 - 0.11 12.9 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 RUS88171.1 - 0.13 12.2 0.7 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Roc PF08477.13 RUS88171.1 - 0.14 12.4 0.2 0.58 10.4 0.1 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_8 PF12780.7 RUS88172.1 - 9.9e-95 316.8 0.0 2.1e-94 315.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 RUS88172.1 - 1.6e-91 306.7 0.0 1.8e-90 303.3 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RUS88172.1 - 5.6e-80 267.6 0.8 5.6e-80 267.6 0.8 3.0 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 RUS88172.1 - 5.4e-55 185.7 0.0 1.6e-54 184.1 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RUS88172.1 - 3.8e-47 161.0 6.3 6.5e-47 160.2 6.3 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RUS88172.1 - 2.4e-39 134.1 0.0 2.4e-38 130.9 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RUS88172.1 - 1.3e-14 54.2 0.0 4.5e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RUS88172.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RUS88172.1 - 0.075 12.8 0.2 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_7 PF17867.1 RUS88172.1 - 0.078 13.2 0.3 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Midasin AAA lid domain LUC7 PF03194.15 RUS88172.1 - 0.26 10.9 14.0 0.81 9.3 0.2 2.6 3 0 0 3 3 3 0 LUC7 N_terminus HrpB7 PF09486.10 RUS88172.1 - 3.7 7.9 12.3 13 6.2 0.3 2.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PDDEXK_1 PF12705.7 RUS88173.1 - 6.9e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily TetR_C_18 PF17923.1 RUS88174.1 - 0.1 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Spore_II_R PF09551.10 RUS88174.1 - 0.35 11.3 2.2 1.4 9.4 2.5 1.8 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DivIC PF04977.15 RUS88175.1 - 0.0015 18.2 4.4 0.0031 17.3 4.4 1.5 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 RUS88175.1 - 0.047 14.1 5.4 0.095 13.2 5.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Tombus_P33 PF08500.10 RUS88175.1 - 0.051 13.5 0.2 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 Tombusvirus p33 NRBF2 PF08961.10 RUS88175.1 - 0.071 12.7 5.1 0.13 11.8 5.1 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 RUS88175.1 - 0.081 13.6 4.5 0.19 12.4 4.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 RUS88175.1 - 0.092 12.9 1.7 6.1 7.0 0.3 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein RE_ApaLI PF09499.10 RUS88175.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease SlyX PF04102.12 RUS88175.1 - 0.11 13.1 0.8 0.28 11.8 0.8 1.7 1 0 0 1 1 1 0 SlyX DUF4201 PF13870.6 RUS88175.1 - 0.14 11.9 7.8 0.29 10.9 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Ribosomal_L27_C PF18471.1 RUS88175.1 - 0.18 11.2 5.8 0.065 12.6 2.7 1.8 2 1 0 2 2 2 0 Ribosomal L27 protein C-terminal domain Tho2 PF11262.8 RUS88175.1 - 0.25 10.5 3.9 6.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 CENP-H PF05837.12 RUS88175.1 - 0.9 10.0 6.3 2 8.9 6.0 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ank_4 PF13637.6 RUS88176.1 - 2e-15 56.9 2.5 2.6e-11 43.8 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS88176.1 - 9e-11 41.8 1.5 1.6e-08 34.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS88176.1 - 1.4e-10 41.1 4.6 0.00016 22.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 RUS88176.1 - 3.9e-10 40.2 1.2 2.9e-09 37.4 1.2 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS88176.1 - 1.4e-09 37.4 0.9 0.00031 20.9 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat NHL PF01436.21 RUS88177.1 - 2.5e-09 36.7 3.3 0.0052 16.8 0.1 4.5 4 0 0 4 4 4 2 NHL repeat zf-RING_UBOX PF13445.6 RUS88177.1 - 1.5e-08 34.5 7.5 4.3e-08 33.0 7.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS88177.1 - 1.5e-08 34.3 8.9 3.4e-08 33.2 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS88177.1 - 2.6e-06 27.5 9.5 1.2e-05 25.3 9.5 2.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RUS88177.1 - 3.8e-05 23.6 8.0 8.4e-05 22.5 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS88177.1 - 6.7e-05 22.7 5.1 0.00018 21.3 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS88177.1 - 8.6e-05 22.3 8.6 0.00037 20.3 8.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS88177.1 - 0.0001 22.5 7.4 0.00022 21.5 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain SBBP PF06739.11 RUS88177.1 - 0.024 14.6 0.2 0.47 10.5 0.2 2.7 3 0 0 3 3 3 0 Beta-propeller repeat Prok-RING_4 PF14447.6 RUS88177.1 - 0.033 14.1 6.0 0.083 12.8 6.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2197 PF09963.9 RUS88177.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2357 PF09823.9 RUS88177.1 - 0.049 12.9 0.5 0.084 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) SGL PF08450.12 RUS88177.1 - 0.069 12.7 0.2 0.44 10.1 0.1 2.3 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region FapA PF03961.13 RUS88177.1 - 0.077 11.6 4.5 0.13 10.8 4.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SBP_bac_8 PF13416.6 RUS88177.1 - 0.11 12.3 0.2 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein NPL PF17800.1 RUS88177.1 - 0.14 12.7 1.0 0.26 11.9 0.1 1.9 2 0 0 2 2 1 0 Nucleoplasmin-like domain Remorin_C PF03763.13 RUS88177.1 - 0.33 10.8 3.4 1.1 9.2 3.4 1.8 1 0 0 1 1 1 0 Remorin, C-terminal region zf-rbx1 PF12678.7 RUS88177.1 - 0.35 11.2 3.6 1.1 9.5 3.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RUS88177.1 - 0.59 10.0 6.2 1.5 8.7 6.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Sec23_Sec24 PF04810.15 RUS88177.1 - 0.65 10.1 2.9 2.3 8.3 0.8 2.7 3 0 0 3 3 2 0 Sec23/Sec24 zinc finger UPF0231 PF06062.11 RUS88177.1 - 1.6 9.1 4.5 4 7.7 4.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) PHD PF00628.29 RUS88177.1 - 2.7 7.9 6.5 12 5.8 6.5 2.2 1 1 0 1 1 1 0 PHD-finger DUF1664 PF07889.12 RUS88177.1 - 3.6 7.6 6.4 8.5 6.4 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf_UBZ PF18439.1 RUS88177.1 - 4.7 6.9 6.9 0.83 9.3 0.2 2.8 3 0 0 3 3 2 0 Ubiquitin-Binding Zinc Finger Mito_carr PF00153.27 RUS88178.1 - 1.9e-34 117.5 0.6 5.4e-14 51.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosom_S12_S23 PF00164.25 RUS88179.1 - 5.9e-27 93.6 0.6 7.6e-27 93.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SAM_1 PF00536.30 RUS88180.1 - 6.9e-07 29.6 0.4 3.9e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS88180.1 - 0.012 15.7 0.4 0.2 11.8 0.1 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PHAT PF09246.10 RUS88180.1 - 0.012 15.4 0.0 0.53 10.1 0.0 2.6 2 0 0 2 2 2 0 PHAT DUF4508 PF14969.6 RUS88180.1 - 0.056 13.7 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) SAM_3 PF18016.1 RUS88180.1 - 0.075 12.9 0.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) LEDGF PF11467.8 RUS88181.1 - 7.5e-17 61.1 0.2 1.5e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) FYVE PF01363.21 RUS88182.1 - 1.3e-08 34.9 11.4 1.3e-08 34.9 11.4 2.5 2 0 0 2 2 2 1 FYVE zinc finger zf-B_box PF00643.24 RUS88182.1 - 0.0036 17.4 8.0 0.0036 17.4 8.0 3.1 3 0 0 3 3 3 2 B-box zinc finger IBR PF01485.21 RUS88182.1 - 2.6 8.4 28.0 0.6 10.4 8.3 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain SNF PF00209.18 RUS88183.1 - 4e-25 88.5 5.4 4.8e-25 88.2 5.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Glycos_transf_4 PF00953.21 RUS88183.1 - 0.11 12.5 0.9 0.13 12.2 0.9 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 Glycophorin_A PF01102.18 RUS88183.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 1 0 1 1 1 0 Glycophorin A SNF PF00209.18 RUS88184.1 - 2.6e-37 128.7 5.8 2.9e-37 128.5 5.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ion_trans PF00520.31 RUS88185.1 - 6.1e-139 461.2 47.9 8.9e-66 221.6 6.0 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 RUS88185.1 - 5.7e-08 31.9 49.1 2.4e-06 26.5 7.2 6.1 5 1 1 6 6 6 5 Polycystin cation channel CENP-N PF05238.13 RUS88187.1 - 0.0022 17.4 6.7 20 4.3 16.8 2.0 2 1 0 2 2 2 0 Kinetochore protein CHL4 like Utp14 PF04615.13 RUS88187.1 - 0.0025 16.5 16.1 0.0025 16.5 16.1 3.0 2 1 0 2 2 1 1 Utp14 protein Eapp_C PF10238.9 RUS88187.1 - 0.0025 17.9 8.9 0.0025 17.9 8.9 2.7 2 1 0 2 2 1 1 E2F-associated phosphoprotein NARP1 PF12569.8 RUS88187.1 - 0.0059 15.6 24.4 0.0059 15.6 24.4 1.5 2 0 0 2 2 1 1 NMDA receptor-regulated protein 1 GIDA_assoc PF13932.6 RUS88187.1 - 0.035 14.3 5.5 0.042 14.0 5.5 1.2 1 0 0 1 1 1 0 GidA associated domain DUF4228 PF14009.6 RUS88187.1 - 0.054 13.9 6.8 0.066 13.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) MDM10 PF12519.8 RUS88187.1 - 0.075 11.9 6.3 0.082 11.8 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RMP PF14996.6 RUS88187.1 - 0.44 10.8 17.9 1.8 8.8 17.9 2.0 1 1 0 1 1 1 0 Retinal Maintenance OATP PF03137.20 RUS88187.1 - 0.52 8.5 7.6 0.6 8.3 7.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_U57 PF05582.12 RUS88187.1 - 0.54 9.5 13.1 0.8 8.9 13.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RPOL_N PF14700.6 RUS88187.1 - 0.58 9.5 18.1 0.8 9.0 18.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal AF-4 PF05110.13 RUS88187.1 - 0.62 8.1 24.8 0.65 8.0 24.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Otopetrin PF03189.13 RUS88187.1 - 0.7 8.6 2.3 0.73 8.6 2.3 1.1 1 0 0 1 1 1 0 Otopetrin DUF4770 PF15994.5 RUS88187.1 - 0.86 9.8 15.5 1.4 9.1 15.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) EMC3_TMCO1 PF01956.16 RUS88187.1 - 1.3 8.8 12.1 1.6 8.5 12.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ndc1_Nup PF09531.10 RUS88187.1 - 1.6 7.3 8.0 1.8 7.2 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2828 PF11443.8 RUS88187.1 - 1.7 6.7 22.5 2.3 6.2 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4569 PF15133.6 RUS88187.1 - 1.9 8.1 9.5 2.5 7.7 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4551 PF15087.6 RUS88187.1 - 2 7.1 8.8 2.2 7.0 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RNA_pol_Rpc4 PF05132.14 RUS88187.1 - 2 8.8 29.5 4.3 7.8 20.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 EIIBC-GUT_N PF03612.14 RUS88187.1 - 2.3 7.9 15.6 3.8 7.2 15.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_11 PF13086.6 RUS88187.1 - 2.3 7.9 16.7 3.6 7.3 16.7 1.3 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 RUS88187.1 - 3.2 7.4 21.1 0.22 11.2 16.1 1.6 2 0 0 2 2 2 0 Connexin Hid1 PF12722.7 RUS88187.1 - 3.9 5.5 10.7 5.5 5.0 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GCD14 PF08704.10 RUS88187.1 - 4.8 6.8 9.4 7.5 6.1 9.4 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Sec62 PF03839.16 RUS88187.1 - 5.4 6.5 25.7 11 5.5 25.7 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Membralin PF09746.9 RUS88187.1 - 6.5 5.7 8.5 8.1 5.4 8.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein BSMAP PF12280.8 RUS88187.1 - 6.6 6.9 9.1 0.18 12.0 2.9 1.7 2 0 0 2 2 1 0 Brain specific membrane anchored protein Band_3_cyto PF07565.13 RUS88187.1 - 7.1 6.3 10.8 9.6 5.9 10.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 RUS88187.1 - 7.4 6.6 11.5 12 5.9 11.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 RUS88187.1 - 7.7 5.2 12.3 9.8 4.9 12.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 RUS88187.1 - 9.9 5.1 8.8 13 4.7 8.8 1.1 1 0 0 1 1 1 0 CLN3 protein AF-4 PF05110.13 RUS88189.1 - 6.6e-06 24.6 2.6 6.6e-06 24.6 2.6 2.0 1 1 1 2 2 2 1 AF-4 proto-oncoprotein Apt1 PF10351.9 RUS88189.1 - 5 5.9 12.8 6.6 5.5 12.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Beta-lactamase PF00144.24 RUS88190.1 - 2.5e-28 99.3 0.1 4.4e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF572 PF04502.13 RUS88190.1 - 4.6 6.8 31.2 7.2 6.1 31.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_LBD PF02931.23 RUS88191.1 - 1.2e-25 90.3 0.4 1.5e-25 90.0 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain p450 PF00067.22 RUS88192.1 - 5.8e-18 64.9 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS88193.1 - 8.5e-55 186.3 0.0 1.2e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5318 PF17249.2 RUS88193.1 - 0.11 12.3 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5318) T-box PF00907.22 RUS88194.1 - 6.2e-61 205.9 0.0 1.1e-60 205.1 0.0 1.4 1 0 0 1 1 1 1 T-box Fibrinogen_BP PF08017.11 RUS88197.1 - 1.6e-05 23.5 0.0 3.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Fibrinogen binding protein Pro-NT_NN PF07421.11 RUS88197.1 - 0.14 12.4 9.6 1.8 8.8 1.4 3.5 2 1 1 3 3 3 0 Neurotensin/neuromedin N precursor IRF-3 PF10401.9 RUS88197.1 - 0.85 9.4 6.3 49 3.7 0.1 4.3 2 1 3 5 5 5 0 Interferon-regulatory factor 3 Hpt PF01627.23 RUS88197.1 - 2.9 8.2 20.4 0.46 10.8 0.7 5.9 2 2 2 4 4 4 0 Hpt domain Mis14 PF08641.12 RUS88197.1 - 5.3 7.4 5.2 85 3.5 1.2 3.6 2 1 2 4 4 4 0 Kinetochore protein Mis14 like NADH-UOR_E PF16514.5 RUS88198.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Amastin PF07344.11 RUS88198.1 - 0.13 12.1 1.7 0.16 11.8 1.7 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein RVT_1 PF00078.27 RUS88200.1 - 7.8e-07 28.8 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arylesterase PF01731.20 RUS88200.1 - 0.0065 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Arylesterase CHB_HEX_C PF03174.13 RUS88200.1 - 0.14 12.2 0.0 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain SMBP PF16785.5 RUS88201.1 - 0.0065 16.7 1.3 37 4.6 0.0 3.6 4 0 0 4 4 4 3 Small metal-binding protein FIVAR PF07554.13 RUS88201.1 - 0.077 13.8 1.5 88 4.0 0.1 3.2 3 0 0 3 3 3 0 FIVAR domain zf-CCHC_5 PF14787.6 RUS88202.1 - 0.068 12.9 3.7 0.077 12.7 0.4 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Zn_ribbon_SprT PF17283.2 RUS88202.1 - 7.5 6.5 10.1 22 5.0 4.2 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain SOUL PF04832.12 RUS88203.1 - 7.3e-43 146.6 0.0 8.6e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Myotub-related PF06602.14 RUS88205.1 - 9.8e-67 225.4 3.8 3.4e-53 180.8 3.5 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 RUS88205.1 - 3.7e-10 39.6 0.4 9.3e-10 38.4 0.4 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein PMT2_N PF17987.1 RUS88205.1 - 0.035 14.3 0.0 8.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF2529 PF10740.9 RUS88205.1 - 0.036 13.7 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Neur_chan_LBD PF02931.23 RUS88206.1 - 7.8e-36 123.5 0.1 1e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS88206.1 - 1.2e-18 68.1 0.0 2.1e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PC4 PF02229.16 RUS88207.1 - 1.4e-23 82.3 0.2 2.6e-23 81.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CCDC106 PF15794.5 RUS88207.1 - 2.1 8.0 6.8 2.8 7.6 6.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 4F5 PF04419.14 RUS88208.1 - 4.2e-13 49.9 6.5 9.1e-13 48.9 6.5 1.6 1 0 0 1 1 1 1 4F5 protein family RSF PF14876.6 RUS88208.1 - 0.16 10.9 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator FERM_N PF09379.10 RUS88209.1 - 8.1e-18 64.1 0.5 7.9e-17 61.0 0.4 2.6 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.10 RUS88209.1 - 4.3e-16 59.1 0.6 1.1e-15 57.8 0.6 1.7 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 RUS88209.1 - 5.3e-13 48.8 0.9 1.6e-12 47.3 0.9 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 RUS88209.1 - 2.6e-12 47.2 1.5 5.4e-11 42.9 0.2 3.0 2 1 0 2 2 2 1 FERM central domain ASFV_J13L PF05568.11 RUS88209.1 - 0.38 10.5 2.5 6.2 6.5 0.3 2.4 1 1 1 2 2 2 0 African swine fever virus J13L protein FlxA PF14282.6 RUS88209.1 - 0.94 9.5 9.0 5.1 7.2 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF2043 PF09740.9 RUS88210.1 - 7.7e-35 119.8 1.3 1.5e-34 118.9 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) Cnd3 PF12719.7 RUS88210.1 - 0.048 12.9 1.3 0.78 8.9 0.1 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Ion_trans PF00520.31 RUS88211.1 - 0.00086 18.6 1.4 0.0013 18.0 1.4 1.3 1 0 0 1 1 1 1 Ion transport protein NMT_C PF02799.15 RUS88212.1 - 1.4e-80 269.7 0.2 2e-80 269.2 0.2 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RUS88212.1 - 7.6e-75 250.1 0.0 2.2e-74 248.6 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 RUS88212.1 - 1.3e-06 28.6 0.0 4.5e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 RUS88212.1 - 0.0034 17.5 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS88212.1 - 0.011 15.6 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1387 PF07139.11 RUS88212.1 - 0.31 10.7 8.6 0.45 10.2 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) EF-hand_1 PF00036.32 RUS88213.1 - 1.3e-16 58.8 1.4 0.00013 21.3 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RUS88213.1 - 7.9e-16 58.3 9.5 4.1e-13 49.6 0.4 3.4 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS88213.1 - 2e-12 46.0 1.5 0.00055 19.3 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 RUS88213.1 - 7.4e-12 44.2 5.7 0.00041 20.1 0.0 4.8 5 1 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 RUS88213.1 - 2.9e-10 39.9 8.1 0.0013 18.5 0.1 4.2 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_11 PF08976.11 RUS88213.1 - 0.0016 19.3 1.3 0.78 10.6 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain DUF3388 PF11868.8 RUS88213.1 - 0.0025 17.2 0.1 0.0061 15.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) Xpo1 PF08389.12 RUS88213.1 - 0.17 12.0 0.5 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Beta_protein PF14350.6 RUS88213.1 - 0.17 11.3 0.4 0.33 10.3 0.4 1.5 1 1 0 1 1 1 0 Beta protein SPARC_Ca_bdg PF10591.9 RUS88213.1 - 0.52 10.6 4.0 0.63 10.4 0.4 2.7 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region NRBF2_MIT PF17169.4 RUS88215.1 - 3e-17 62.6 1.2 3e-17 62.6 1.2 1.8 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 RUS88215.1 - 0.00088 19.3 0.4 0.00088 19.3 0.4 2.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain COMMD1_N PF17221.3 RUS88215.1 - 0.047 14.0 0.6 0.047 14.0 0.6 2.1 2 1 0 2 2 2 0 COMMD1 N-terminal domain TPR_1 PF00515.28 RUS88215.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_IE-1 PF05290.11 RUS88215.1 - 0.11 12.5 0.4 4.4 7.2 0.0 2.4 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Pyridoxal_deC PF00282.19 RUS88216.1 - 2.5e-102 342.4 0.0 3.1e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RUS88216.1 - 8.6e-05 22.0 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RUS88216.1 - 0.0041 16.3 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 RUS88216.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Y_phosphatase PF00102.27 RUS88217.1 - 7.5e-100 333.3 0.3 3.9e-77 259.0 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 RUS88217.1 - 1.1e-06 28.9 0.1 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 1 Fibronectin type III domain PTP_tm PF18861.1 RUS88217.1 - 0.0017 18.4 0.6 0.0038 17.2 0.0 1.8 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 RUS88217.1 - 0.0019 17.6 4.0 0.0033 16.8 4.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 RUS88217.1 - 0.03 14.6 0.1 0.068 13.5 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 RUS88217.1 - 0.038 12.7 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 RUS88217.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF5113 PF17140.4 RUS88217.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) DUF4448 PF14610.6 RUS88217.1 - 0.12 12.2 0.7 0.29 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Y_phosphatase3 PF13350.6 RUS88217.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family OAD_gamma PF04277.13 RUS88217.1 - 0.19 12.4 0.1 0.41 11.3 0.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Insulin_TMD PF17870.1 RUS88217.1 - 0.39 10.8 2.5 0.86 9.7 2.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 RUS88217.1 - 4 7.3 9.9 0.099 12.4 2.7 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 GWT1 PF06423.12 RUS88219.1 - 6.7e-09 36.0 0.2 6.7e-09 36.0 0.2 3.3 3 1 0 3 3 3 1 GWT1 MFS_3 PF05977.13 RUS88219.1 - 0.053 11.9 3.3 0.18 10.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2062 PF09835.9 RUS88219.1 - 6 6.7 9.0 0.31 10.9 2.4 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Androgen_recep PF02166.16 RUS88220.1 - 0.006 15.5 11.3 0.0076 15.2 11.3 1.2 1 0 0 1 1 1 1 Androgen receptor TFIIA PF03153.13 RUS88220.1 - 0.012 15.7 14.2 0.012 15.6 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MG4 PF17789.1 RUS88220.1 - 0.1 12.7 1.4 0.17 12.1 1.4 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG4 Enolase_N PF03952.16 RUS88220.1 - 0.11 12.6 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Enolase, N-terminal domain PAT1 PF09770.9 RUS88220.1 - 0.25 9.6 9.3 0.25 9.6 9.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 RUS88220.1 - 1.9 8.5 4.6 2.2 8.3 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 RUS88220.1 - 9.8 4.8 6.3 11 4.6 6.3 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 RUS88221.1 - 5.3e-62 209.6 0.0 6.5e-61 206.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88221.1 - 3.8e-32 111.6 0.0 2.3e-30 105.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS88221.1 - 2.9e-08 33.4 0.0 8.1e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS88221.1 - 0.0012 18.2 0.3 0.0025 17.2 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RUS88221.1 - 0.038 13.0 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Citrate_synt PF00285.21 RUS88221.1 - 0.076 12.1 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain APH PF01636.23 RUS88221.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ets PF00178.22 RUS88222.1 - 5.8e-37 126.0 1.0 5.8e-37 126.0 1.0 2.1 2 0 0 2 2 2 1 Ets-domain HSF_DNA-bind PF00447.17 RUS88222.1 - 0.13 12.9 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding CDC24 PF06395.11 RUS88222.1 - 0.19 12.0 0.1 0.43 10.9 0.0 1.6 2 0 0 2 2 2 0 CDC24 Calponin Ets PF00178.22 RUS88223.1 - 1.7e-22 79.7 13.9 8.6e-20 71.0 0.1 3.1 3 0 0 3 3 3 2 Ets-domain SAM_PNT PF02198.16 RUS88224.1 - 4.5e-28 97.0 0.3 7.3e-28 96.4 0.3 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AAA_6 PF12774.7 RUS88225.1 - 0.2 10.6 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Tetraspanin PF00335.20 RUS88226.1 - 1.1e-14 54.7 2.8 1.4e-14 54.4 2.8 1.0 1 0 0 1 1 1 1 Tetraspanin family PsiA PF06952.11 RUS88227.1 - 0.014 14.6 0.2 0.02 14.2 0.2 1.2 1 0 0 1 1 1 0 PsiA protein SLM4 PF16818.5 RUS88228.1 - 0.18 11.8 4.0 0.31 11.0 4.0 1.4 1 1 0 1 1 1 0 Protein SLM4 CSRNP_N PF16019.5 RUS88228.1 - 0.45 10.4 8.5 0.52 10.2 8.5 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TFIIA PF03153.13 RUS88228.1 - 0.61 10.0 18.1 0.71 9.8 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAS20 PF02064.15 RUS88228.1 - 0.97 9.5 5.2 1.3 9.1 5.2 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor HTH_Tnp_Tc5 PF03221.16 RUS88229.1 - 4.7e-32 109.8 5.0 2.8e-11 43.3 0.1 4.0 3 1 0 3 3 3 3 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 RUS88229.1 - 9.5e-26 89.2 19.7 9.6e-08 31.5 2.3 5.5 5 0 0 5 5 5 4 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 RUS88229.1 - 8.2e-20 70.0 22.7 2.3e-05 24.1 0.4 7.6 7 1 0 7 7 7 4 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 RUS88229.1 - 1.3e-13 50.1 6.1 0.0066 15.8 0.1 5.3 5 0 0 5 5 5 4 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 RUS88229.1 - 5.7e-13 48.4 15.3 0.00013 21.7 0.5 6.0 6 0 0 6 6 5 2 Helix-turn-helix domain HTH_24 PF13412.6 RUS88229.1 - 4.9e-11 42.0 5.7 0.0035 16.9 0.1 5.7 6 0 0 6 6 6 3 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 RUS88229.1 - 1.2e-08 34.9 4.7 0.025 14.6 0.0 4.4 4 0 0 4 4 4 2 Helix-turn-helix HTH_Tnp_4 PF13613.6 RUS88229.1 - 1.3e-08 34.4 0.1 0.23 11.2 0.0 4.5 4 0 0 4 4 4 2 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 RUS88229.1 - 6.7e-08 31.9 5.5 1.7 8.2 0.1 4.8 4 0 0 4 4 4 3 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 RUS88229.1 - 1.2e-07 32.0 20.9 0.025 14.9 0.1 6.4 6 0 0 6 6 6 2 Transposase HTH_7 PF02796.15 RUS88229.1 - 2.1e-07 30.9 8.4 0.16 12.1 0.1 4.6 4 0 0 4 4 4 2 Helix-turn-helix domain of resolvase HTH_26 PF13443.6 RUS88229.1 - 3.2e-07 30.7 8.3 0.031 14.7 0.3 4.4 4 0 0 4 4 4 2 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 RUS88229.1 - 3.3e-07 30.0 0.7 0.28 11.0 0.0 4.1 4 0 0 4 4 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 RUS88229.1 - 4.2e-07 29.8 0.8 0.25 11.3 0.0 4.7 4 0 0 4 4 4 1 MarR family HTH_29 PF13551.6 RUS88229.1 - 2.1e-06 27.6 19.7 0.046 13.7 1.6 7.5 7 1 0 7 7 7 1 Winged helix-turn helix DUF3853 PF12964.7 RUS88229.1 - 4.8e-06 26.6 0.7 0.74 10.0 0.1 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3853) HTH_31 PF13560.6 RUS88229.1 - 8e-06 26.1 12.2 2.2 8.7 0.0 6.4 6 0 0 6 6 6 2 Helix-turn-helix domain HTH_11 PF08279.12 RUS88229.1 - 1.4e-05 24.9 7.3 0.46 10.5 0.1 3.8 4 0 0 4 4 3 2 HTH domain HTH_35 PF13693.6 RUS88229.1 - 1.5e-05 25.0 8.5 0.54 10.3 0.0 4.7 4 0 0 4 4 4 2 Winged helix-turn-helix DNA-binding MarR PF01047.22 RUS88229.1 - 4.3e-05 23.3 1.9 0.82 9.7 0.0 4.6 4 0 0 4 4 4 1 MarR family HTH_5 PF01022.20 RUS88229.1 - 4.5e-05 23.2 0.5 0.022 14.6 0.1 4.1 4 0 0 4 4 4 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 RUS88229.1 - 4.6e-05 23.5 14.4 1.2 9.4 0.2 6.5 6 1 0 6 6 5 2 Helix-turn-helix domain HTH_AsnC-type PF13404.6 RUS88229.1 - 7.3e-05 22.5 2.0 1.4 8.8 0.0 4.7 5 0 0 5 5 4 1 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 RUS88229.1 - 0.0001 22.0 0.3 1.5 8.6 0.0 3.5 3 0 0 3 3 3 2 helix-turn-helix, Psq domain LacI PF00356.21 RUS88229.1 - 0.00032 20.4 5.5 0.64 9.9 0.1 3.7 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family Trp_repressor PF01371.19 RUS88229.1 - 0.00047 20.2 9.3 0.72 10.0 0.0 4.5 4 0 0 4 4 4 1 Trp repressor protein Mor PF08765.11 RUS88229.1 - 0.00047 20.1 0.5 13 5.9 0.0 4.5 4 0 0 4 4 4 0 Mor transcription activator family HTH_37 PF13744.6 RUS88229.1 - 0.00054 19.9 3.8 0.27 11.2 0.1 4.2 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_10 PF04967.12 RUS88229.1 - 0.002 17.9 1.5 3.2 7.6 0.0 4.4 4 0 0 4 4 4 1 HTH DNA binding domain YdaS_antitoxin PF15943.5 RUS88229.1 - 0.0024 17.7 0.4 5.4 7.0 0.0 4.1 4 0 0 4 4 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_22 PF13309.6 RUS88229.1 - 0.0031 17.5 1.9 31 4.8 0.0 4.5 4 0 0 4 4 3 0 HTH domain Sigma70_r4_2 PF08281.12 RUS88229.1 - 0.0034 17.0 0.9 5.2 6.8 0.0 3.7 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_AraC PF00165.23 RUS88229.1 - 0.024 14.7 0.1 14 5.9 0.0 3.3 3 0 0 3 3 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_19 PF12844.7 RUS88229.1 - 0.027 14.5 2.2 1.1 9.3 0.2 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain Mga PF05043.13 RUS88229.1 - 0.03 14.9 5.2 17 6.1 0.1 4.4 4 0 0 4 4 4 0 Mga helix-turn-helix domain PgaD PF13994.6 RUS88229.1 - 0.032 14.3 1.5 12 5.9 0.0 4.0 4 0 0 4 4 3 0 PgaD-like protein RWP-RK PF02042.15 RUS88229.1 - 0.072 13.1 0.5 2.6 8.1 0.2 2.8 2 0 0 2 2 2 0 RWP-RK domain Phage_CI_repr PF07022.13 RUS88229.1 - 0.091 12.9 0.1 1.9 8.6 0.0 2.6 3 0 0 3 3 2 0 Bacteriophage CI repressor helix-turn-helix domain LysM PF01476.20 RUS88229.1 - 0.11 12.6 0.1 26 5.0 0.0 3.6 4 0 0 4 4 3 0 LysM domain HTH_Crp_2 PF13545.6 RUS88229.1 - 0.11 12.4 4.3 16 5.6 0.0 4.1 5 0 0 5 5 2 0 Crp-like helix-turn-helix domain IF2_N PF04760.15 RUS88229.1 - 0.13 12.1 5.7 4.4 7.2 0.3 4.3 4 0 0 4 4 3 0 Translation initiation factor IF-2, N-terminal region DUF2316 PF10078.9 RUS88229.1 - 0.22 11.8 3.6 5.6 7.3 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) GerE PF00196.19 RUS88229.1 - 0.23 11.0 1.5 0.94 9.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_6 PF01418.17 RUS88229.1 - 0.27 11.3 1.9 4.9 7.2 0.1 3.5 4 0 0 4 4 3 0 Helix-turn-helix domain, rpiR family TrmB PF01978.19 RUS88229.1 - 0.27 11.2 2.3 9.2 6.2 0.0 3.2 4 0 0 4 4 2 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.7 RUS88229.1 - 0.3 11.3 2.5 14 5.9 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_36 PF13730.6 RUS88229.1 - 0.33 10.9 5.2 0.85 9.6 0.1 3.6 4 0 0 4 4 3 0 Helix-turn-helix domain Terminase_4 PF05119.12 RUS88229.1 - 0.76 10.2 4.2 32 5.1 0.0 3.8 4 0 0 4 4 3 0 Phage terminase, small subunit zf-ISL3 PF14690.6 RUS88229.1 - 3.7 8.3 7.0 2.1 9.1 2.7 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 KORA PF16509.5 RUS88229.1 - 4.8 7.5 5.6 5.4 7.4 0.2 3.3 4 0 0 4 4 2 0 TrfB plasmid transcriptional repressor Cro PF09048.10 RUS88229.1 - 8.3 6.5 6.9 72 3.5 0.1 3.7 4 0 0 4 4 3 0 Cro LRR_9 PF14580.6 RUS88230.1 - 1.4e-09 37.7 1.2 0.0025 17.3 0.0 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_4 PF12799.7 RUS88230.1 - 5.5e-07 29.8 18.1 0.0019 18.6 0.1 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS88230.1 - 1.3e-05 24.8 11.1 0.0024 17.6 0.1 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 RUS88230.1 - 0.22 11.7 3.8 8.2 6.8 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Clathrin_lg_ch PF01086.17 RUS88231.1 - 3.5e-55 187.6 14.2 4.5e-55 187.2 14.2 1.1 1 0 0 1 1 1 1 Clathrin light chain ASC PF00858.24 RUS88231.1 - 0.48 9.3 6.9 0.67 8.8 6.9 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel YtxH PF12732.7 RUS88231.1 - 0.76 10.3 4.6 1.5 9.4 4.6 1.5 1 0 0 1 1 1 0 YtxH-like protein DUF2052 PF09747.9 RUS88231.1 - 3.1 7.9 19.6 3.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) U79_P34 PF03064.16 RUS88231.1 - 3.6 6.9 14.5 5.4 6.3 14.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Tubulin PF00091.25 RUS88232.1 - 2.6e-68 230.1 0.0 3.6e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS88232.1 - 3.7e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS88232.1 - 0.00026 20.7 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 RUS88233.1 - 2.3e-67 227.0 0.0 3.1e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS88233.1 - 5.2e-51 172.1 0.0 8e-51 171.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS88233.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GATA PF00320.27 RUS88234.1 - 1.2e-27 95.2 16.4 7.3e-16 57.5 6.0 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 RUS88234.1 - 4.3e-05 22.9 12.5 0.0068 15.9 0.8 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 RUS88234.1 - 0.0001 22.4 4.6 0.17 12.0 0.2 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Vps36-NZF-N PF16988.5 RUS88234.1 - 0.015 14.6 1.4 0.015 14.6 1.4 3.2 1 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RRN7 PF11781.8 RUS88234.1 - 0.03 14.0 13.4 0.19 11.5 3.0 3.2 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 RUS88234.1 - 0.14 12.2 11.9 13 5.9 12.4 2.9 1 1 1 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 RUS88234.1 - 0.18 11.8 13.6 0.071 13.0 3.0 3.2 3 0 0 3 3 3 0 Nudix N-terminal Rubredoxin_2 PF18073.1 RUS88234.1 - 0.19 11.5 12.6 7.9 6.3 0.3 4.3 4 0 0 4 4 4 0 Rubredoxin metal binding domain eIF-5_eIF-2B PF01873.17 RUS88234.1 - 0.23 11.3 9.4 2.1 8.3 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 RUS88234.1 - 0.68 10.1 8.6 3.5 7.9 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Apocytochr_F_N PF16639.5 RUS88234.1 - 0.76 10.0 3.0 1.9 8.8 0.1 2.4 1 1 2 3 3 3 0 Apocytochrome F, N-terminal DUF2387 PF09526.10 RUS88234.1 - 1.3 9.3 9.0 4 7.6 0.8 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) C1_2 PF03107.16 RUS88234.1 - 4.3 7.7 9.9 13 6.2 2.3 3.0 1 1 1 2 2 2 0 C1 domain OrfB_Zn_ribbon PF07282.11 RUS88234.1 - 4.5 7.3 15.5 1.2 9.1 1.3 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Elf1 PF05129.13 RUS88234.1 - 9.6 6.3 14.4 1.1 9.4 0.7 3.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 RUS88234.1 - 9.8 5.8 17.6 5.6 6.5 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain tRNA-synt_1c PF00749.21 RUS88236.1 - 7.5e-33 113.7 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c PF00749.21 RUS88237.1 - 1.8e-22 79.7 0.0 2.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Zincin_1 PF06262.11 RUS88237.1 - 0.11 12.5 0.0 2 8.6 0.0 2.4 3 0 0 3 3 3 0 Zincin-like metallopeptidase Peptidase_C1 PF00112.23 RUS88238.1 - 4e-49 167.7 5.5 5.8e-49 167.1 5.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 RUS88238.1 - 1.7e-12 47.0 0.0 3.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 RUS88238.1 - 0.0022 16.9 1.9 0.47 9.2 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family zf-C2H2_jaz PF12171.8 RUS88239.1 - 0.13 12.5 1.0 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CAMSAP_CC1 PF17095.5 RUS88243.1 - 7.7e-15 54.5 9.9 7.7e-15 54.5 9.9 3.6 2 1 0 2 2 2 1 Spectrin-binding region of Ca2+-Calmodulin CAMSAP_CKK PF08683.11 RUS88243.1 - 1.5e-08 34.8 0.1 3.1e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF4668 PF15701.5 RUS88244.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) zf-C2H2_2 PF12756.7 RUS88244.1 - 0.22 11.9 4.1 0.6 10.5 0.5 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 RUS88245.1 - 7.6e-15 54.3 64.9 1.2e-05 24.9 1.5 7.4 7 0 0 7 7 7 6 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS88245.1 - 9.7e-14 51.1 41.2 0.00034 20.9 5.9 6.9 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS88245.1 - 2.1e-08 34.1 64.4 0.0017 18.7 5.3 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_7 PF15269.6 RUS88245.1 - 0.0041 17.2 0.5 0.0041 17.2 0.5 5.9 2 2 4 6 6 6 2 Zinc-finger zf-C2H2_jaz PF12171.8 RUS88245.1 - 1.4 9.3 16.7 0.91 9.9 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Lamp PF01299.17 RUS88246.1 - 2.2e-05 24.3 0.0 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) CDC45 PF02724.14 RUS88247.1 - 0.00029 19.3 14.0 0.00033 19.1 14.0 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 RUS88247.1 - 0.0012 18.3 18.1 0.0014 18.2 18.1 1.2 1 0 0 1 1 1 1 SDA1 RRN3 PF05327.11 RUS88247.1 - 0.0027 16.3 19.6 0.0033 16.1 19.6 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 RUS88247.1 - 0.0038 15.7 12.7 0.0043 15.6 12.7 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2294 PF10057.9 RUS88247.1 - 0.0041 17.2 4.7 1.8 8.8 0.7 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2294) Trigger_C PF05698.14 RUS88247.1 - 0.18 11.8 2.0 0.25 11.4 2.0 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus IFRD PF05004.13 RUS88247.1 - 0.4 9.7 8.3 0.53 9.3 8.3 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Roughex PF06020.11 RUS88247.1 - 1.9 7.5 9.6 2.2 7.3 9.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein PDDEXK_6 PF04720.12 RUS88247.1 - 2 8.3 8.5 3.6 7.5 8.5 1.5 1 1 0 1 1 1 0 PDDEXK-like family of unknown function Fer4_22 PF17179.4 RUS88247.1 - 2.9 8.8 6.6 10 7.1 0.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF3490 PF11995.8 RUS88247.1 - 4.3 7.1 8.5 36 4.1 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) CDC4_D PF16856.5 RUS88247.1 - 8.2 6.4 19.8 11 6.0 1.1 3.7 2 1 2 4 4 4 0 Cell division control protein 4 dimerisation domain YMF19 PF02326.15 RUS88247.1 - 9.4 7.1 6.6 33 5.4 3.0 2.4 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF4684 PF15736.5 RUS88249.1 - 0.073 11.7 0.1 0.073 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) SOAR PF16533.5 RUS88249.1 - 0.13 12.2 0.4 0.15 12.0 0.4 1.2 1 1 0 1 1 1 0 STIM1 Orai1-activating region CTU2 PF10288.9 RUS88250.1 - 0.036 14.3 1.0 0.036 14.3 1.0 3.2 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 FYDLN_acid PF09538.10 RUS88250.1 - 3.1 8.5 16.2 4.4 8.0 8.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 RUS88250.1 - 5.9 6.8 46.8 1.4 8.8 19.4 2.2 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EGF PF00008.27 RUS88251.1 - 5e-10 39.5 21.1 3.4e-05 24.1 6.1 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 RUS88251.1 - 2.2e-07 31.1 21.4 0.0019 18.5 6.2 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS88251.1 - 7e-07 29.7 18.7 0.00094 19.7 3.8 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.24 RUS88251.1 - 0.071 13.3 17.8 0.38 10.9 5.4 2.6 2 1 0 2 2 2 0 Laminin EGF domain zf-C2H2 PF00096.26 RUS88252.1 - 7.5e-11 41.9 32.9 5.7e-05 23.3 3.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS88252.1 - 1.7e-08 34.5 7.6 6.9e-08 32.6 1.0 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS88252.1 - 0.0001 22.8 9.6 0.0014 19.3 1.7 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger FYDLN_acid PF09538.10 RUS88252.1 - 0.034 14.8 9.1 0.18 12.5 9.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-LYAR PF08790.11 RUS88252.1 - 0.074 13.0 2.6 2.4 8.1 0.2 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-met PF12874.7 RUS88252.1 - 0.83 10.1 10.1 14 6.2 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS88252.1 - 1.4 9.0 16.0 0.17 11.9 0.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos PF03372.23 RUS88253.1 - 2.4e-12 46.9 0.0 1.2e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS88253.1 - 0.0016 18.3 0.1 0.0047 16.8 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Senescence PF06911.12 RUS88254.1 - 2.8e-43 148.3 6.9 4.9e-43 147.6 6.9 1.4 1 0 0 1 1 1 1 Senescence-associated protein FAM25 PF15825.5 RUS88254.1 - 0.014 15.7 1.9 0.069 13.5 0.3 2.7 2 0 0 2 2 2 0 FAM25 family MIT PF04212.18 RUS88254.1 - 0.067 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Lectin_C PF00059.21 RUS88255.1 - 1.2e-06 29.2 0.0 1.9e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Anthrax-tox_M PF09156.10 RUS88255.1 - 0.027 13.8 1.3 0.035 13.4 1.3 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Lectin_C PF00059.21 RUS88257.1 - 1.1e-09 39.0 0.0 1.6e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 RUS88258.1 - 1.9e-14 54.3 0.0 9.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 2 Lectin C-type domain SerH PF06873.11 RUS88258.1 - 0.13 11.0 0.0 0.69 8.6 0.0 1.8 2 0 0 2 2 2 0 Cell surface immobilisation antigen SerH Epimerase PF01370.21 RUS88259.1 - 2e-09 37.3 0.0 5.6e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 RUS88259.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ActA PF05058.12 RUS88259.1 - 0.18 10.1 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 ActA Protein Macoilin PF09726.9 RUS88260.1 - 0.013 14.1 40.6 0.016 13.8 40.6 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 RUS88260.1 - 0.12 11.5 31.9 0.15 11.1 31.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CAC1F_C PF16885.5 RUS88260.1 - 0.47 10.1 17.7 0.58 9.8 17.7 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Dapper PF15268.6 RUS88260.1 - 0.47 9.3 37.6 0.54 9.0 37.6 1.1 1 0 0 1 1 1 0 Dapper AF-4 PF05110.13 RUS88260.1 - 0.69 7.9 59.9 0.95 7.5 59.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 7tm_1 PF00001.21 RUS88262.1 - 1.6e-53 181.7 16.7 2.2e-53 181.3 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS88262.1 - 7.2e-07 29.1 10.9 7.2e-07 29.1 10.9 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS88262.1 - 2.4e-06 27.5 12.9 2.4e-06 27.5 12.9 1.9 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 RUS88262.1 - 1.4e-05 24.6 20.4 0.0066 15.9 9.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS88262.1 - 0.0001 21.8 18.8 0.012 15.0 8.4 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv PID PF00640.23 RUS88263.1 - 2.6e-26 92.3 0.0 1e-25 90.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS88263.1 - 1.2e-05 25.4 0.0 3.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine-binding domain SH3_2 PF07653.17 RUS88264.1 - 0.081 12.6 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain RIO1 PF01163.22 RUS88265.1 - 1.5e-07 31.3 2.4 2.5 7.7 0.0 5.0 1 1 4 5 5 5 5 RIO1 family DUF3850 PF12961.7 RUS88265.1 - 0.17 12.0 5.4 4.9 7.3 0.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3850) DUF5051 PF16473.5 RUS88265.1 - 0.18 11.8 0.8 9.7 6.1 0.2 2.7 1 1 1 2 2 2 0 3' exoribonuclease, RNase T-like WW PF00397.26 RUS88266.1 - 3.1e-05 24.0 2.1 6.2e-05 23.0 2.1 1.6 1 0 0 1 1 1 1 WW domain Miga PF10265.9 RUS88267.1 - 0.081 11.9 3.4 0.12 11.3 3.4 1.2 1 0 0 1 1 1 0 Mitoguardin AMP-binding PF00501.28 RUS88269.1 - 1.2e-105 353.5 0.0 1.5e-105 353.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS88269.1 - 2.8e-18 66.7 0.1 5.1e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 RUS88269.1 - 0.013 15.8 0.5 0.03 14.6 0.2 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 RUS88271.1 - 3.6e-33 115.8 0.1 5.6e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RUS88271.1 - 0.00039 20.8 0.0 0.00093 19.6 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 RUS88271.1 - 0.089 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CRAL_TRIO PF00650.20 RUS88272.1 - 1.4e-28 99.6 0.2 2.6e-28 98.7 0.1 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain Motile_Sperm PF00635.26 RUS88272.1 - 7.2e-19 67.7 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain KN_motif PF12075.8 RUS88272.1 - 0.19 11.5 1.5 2.5 8.0 0.2 2.5 2 0 0 2 2 2 0 KN motif 5_nucleotid_C PF02872.18 RUS88273.1 - 4.8e-42 143.9 0.0 1.4e-41 142.3 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RUS88274.1 - 0.0013 19.3 2.3 0.0026 18.3 2.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CPSF_A PF03178.15 RUS88276.1 - 9.2e-85 284.8 0.0 9.1e-83 278.2 0.0 2.6 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.9 RUS88276.1 - 2.7e-37 128.6 0.1 4.7e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term TRP_2 PF08344.11 RUS88277.1 - 3.7e-26 91.1 1.4 1.1e-25 89.6 1.4 1.9 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 RUS88277.1 - 1.9e-22 79.7 12.5 1.9e-22 79.7 12.5 1.6 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RUS88277.1 - 8.7e-11 42.3 1.8 1.1e-06 29.1 0.9 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS88277.1 - 1.5e-10 41.4 0.1 9.8e-06 26.0 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS88277.1 - 1.8e-05 24.9 0.1 1.3 9.5 0.3 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88277.1 - 3.3e-05 23.9 0.9 0.29 11.8 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 RUS88277.1 - 8.9e-05 22.8 0.3 0.78 10.3 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeat PKD_channel PF08016.12 RUS88277.1 - 0.0002 20.1 11.0 0.19 10.4 0.2 3.5 3 0 0 3 3 3 3 Polycystin cation channel Oxidored_q3 PF00499.20 RUS88277.1 - 0.082 12.6 3.1 0.082 12.6 0.3 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3510 PF12022.8 RUS88277.1 - 0.78 10.1 7.5 5.4 7.4 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) MULE PF10551.9 RUS88278.1 - 7.4e-11 42.3 0.0 9.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain DUF5575 PF17738.1 RUS88278.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5575) zf-RanBP PF00641.18 RUS88279.1 - 2.6e-07 29.8 0.2 4.5e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Jnk-SapK_ap_N PF09744.9 RUS88279.1 - 0.00038 20.7 14.7 0.00038 20.7 14.7 3.7 2 2 1 3 3 3 1 JNK_SAPK-associated protein-1 CC2-LZ PF16516.5 RUS88279.1 - 0.0057 17.0 16.9 0.0057 17.0 16.9 4.1 2 2 2 4 4 4 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Leu_zip PF15294.6 RUS88279.1 - 0.019 14.5 0.9 0.019 14.5 0.9 3.2 2 1 1 3 3 3 0 Leucine zipper TSC22 PF01166.18 RUS88279.1 - 0.028 14.7 14.7 0.15 12.4 0.6 4.8 4 1 1 5 5 5 0 TSC-22/dip/bun family DZR PF12773.7 RUS88279.1 - 0.073 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon CCDC144C PF14915.6 RUS88279.1 - 0.15 11.1 34.8 0.018 14.2 25.6 2.4 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region WEMBL PF05701.11 RUS88279.1 - 0.21 10.3 35.2 0.16 10.6 25.5 2.2 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 RUS88279.1 - 0.23 10.3 40.5 0.24 10.2 15.9 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 RUS88279.1 - 0.46 9.9 18.3 0.55 9.7 4.0 3.3 2 1 0 3 3 3 0 Allexivirus 40kDa protein Rubredoxin PF00301.20 RUS88279.1 - 0.89 9.6 6.6 0.6 10.2 1.3 2.4 1 1 2 3 3 3 0 Rubredoxin GramPos_pilinD1 PF16555.5 RUS88279.1 - 1.7 8.8 10.6 0.26 11.5 4.5 2.2 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain NPV_P10 PF05531.12 RUS88279.1 - 3.6 8.1 8.2 12 6.4 0.1 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 RUS88279.1 - 3.6 7.0 40.1 0.14 11.6 1.7 2.7 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Bacillus_HBL PF05791.11 RUS88279.1 - 5.8 6.7 16.9 6.7 6.5 1.4 3.7 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF4094 PF13334.6 RUS88279.1 - 6 7.4 14.9 4.9 7.6 1.3 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Takusan PF04822.13 RUS88279.1 - 8.5 6.3 13.4 0.28 11.1 0.6 3.6 2 1 1 3 3 3 0 Takusan SSF PF00474.17 RUS88280.1 - 5.4e-29 101.3 27.7 5.4e-29 101.3 27.7 1.8 2 1 0 2 2 2 1 Sodium:solute symporter family Astro_capsid_p PF12226.8 RUS88281.1 - 0.011 15.0 13.6 0.015 14.5 13.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 RUS88281.1 - 0.015 13.6 15.5 0.018 13.3 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 RUS88281.1 - 0.34 9.0 36.8 0.42 8.7 36.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RUS88281.1 - 0.69 8.4 17.1 0.82 8.1 17.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 RUS88281.1 - 1.3 8.7 8.6 2.1 8.1 8.6 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 RUS88281.1 - 1.7 8.0 20.6 1.9 7.8 20.6 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS88281.1 - 1.8 7.9 13.0 2.6 7.3 13.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 RUS88281.1 - 2 7.6 9.5 2.3 7.3 9.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.13 RUS88281.1 - 3.6 7.5 23.3 3.9 7.4 23.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.12 RUS88281.1 - 3.8 5.7 7.4 4.8 5.4 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Apt1 PF10351.9 RUS88282.1 - 0.008 15.1 15.6 0.0082 15.0 15.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 RUS88282.1 - 0.016 13.8 14.9 0.017 13.8 14.9 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 RUS88282.1 - 0.084 11.5 11.7 0.093 11.4 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Toxin_TOLIP PF00087.21 RUS88282.1 - 0.094 13.0 6.1 0.33 11.2 6.1 2.0 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Presenilin PF01080.17 RUS88282.1 - 0.095 11.4 4.3 0.11 11.2 4.3 1.1 1 0 0 1 1 1 0 Presenilin GST_N_4 PF17172.4 RUS88282.1 - 0.11 13.2 0.0 0.34 11.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Hid1 PF12722.7 RUS88282.1 - 0.26 9.4 4.7 0.28 9.3 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 RUS88282.1 - 0.34 10.1 33.5 0.46 9.6 33.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sec3_C PF09763.9 RUS88282.1 - 4.3 5.6 6.6 4.5 5.5 6.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Plasmodium_Vir PF05795.11 RUS88282.1 - 5.3 6.4 10.3 7 6.0 10.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BUD22 PF09073.10 RUS88282.1 - 5.7 6.2 18.1 7.5 5.8 18.1 1.1 1 0 0 1 1 1 0 BUD22 HMA PF00403.26 RUS88284.1 - 6e-13 49.0 0.4 6.9e-13 48.8 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain GnsAB_toxin PF08178.11 RUS88284.1 - 0.11 12.5 0.9 0.26 11.2 0.4 1.8 1 1 1 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system MMM1 PF10296.9 RUS88286.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Cadherin PF00028.17 RUS88287.1 - 2.6e-86 284.2 5.3 8.3e-19 67.8 0.1 7.2 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS88287.1 - 3.9e-10 39.4 0.0 8.8e-09 35.1 0.0 3.2 3 0 0 3 3 3 1 Cadherin-like SusE PF14292.6 RUS88287.1 - 0.028 14.6 1.4 69 3.7 0.1 4.7 4 1 0 4 4 4 0 SusE outer membrane protein Y_Y_Y PF07495.13 RUS88287.1 - 0.14 12.1 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Y_Y_Y domain He_PIG PF05345.12 RUS88287.1 - 0.35 11.1 7.9 15 5.9 0.1 5.6 5 1 1 6 6 6 0 Putative Ig domain Sarcoglycan_1 PF04790.13 RUS88290.1 - 2.7e-27 95.8 0.1 2.9e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 RUS88290.1 - 0.003 17.4 0.2 0.0085 16.0 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) G8 PF10162.9 RUS88290.1 - 0.023 14.8 0.2 7.5 6.7 0.0 2.4 1 1 1 2 2 2 0 G8 domain DUF3540 PF12059.8 RUS88290.1 - 0.024 14.5 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Cu_amine_oxidN1 PF07833.11 RUS88290.1 - 0.054 14.0 0.4 2.9 8.5 0.0 2.4 2 1 0 2 2 2 0 Copper amine oxidase N-terminal domain Recep_L_domain PF01030.24 RUS88290.1 - 0.09 12.9 1.4 0.1 12.7 0.2 1.8 2 1 0 2 2 2 0 Receptor L domain PFK PF00365.20 RUS88291.1 - 3.6e-21 75.7 0.0 4.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase PFK PF00365.20 RUS88292.1 - 1.1e-104 349.7 0.1 5.4e-77 258.9 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase bZIP_1 PF00170.21 RUS88293.1 - 0.014 15.5 2.7 0.014 15.5 2.7 8.6 8 2 1 9 9 9 0 bZIP transcription factor NUFIP1 PF10453.9 RUS88293.1 - 0.02 14.7 2.3 0.046 13.6 0.3 2.8 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GEN1_C PF18380.1 RUS88294.1 - 0.13 13.1 1.1 0.42 11.5 1.1 1.8 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Presenilin PF01080.17 RUS88294.1 - 1.5 7.6 6.2 2.1 7.1 6.2 1.2 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 RUS88296.1 - 5.6 6.5 23.0 8 6.0 23.0 1.3 1 0 0 1 1 1 0 PPP4R2 PDZ PF00595.24 RUS88297.1 - 1.3e-08 35.0 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS88297.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS88297.1 - 2.8e-05 24.3 0.0 7.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 PDZ domain FERM_M PF00373.18 RUS88297.1 - 3.4e-05 24.2 0.4 5.9e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 FERM central domain WW PF00397.26 RUS88298.1 - 7.7e-07 29.1 10.1 2.5e-05 24.3 0.2 3.4 3 0 0 3 3 3 3 WW domain DUF2205 PF10224.9 RUS88299.1 - 1.8e-25 88.7 0.6 2.4e-25 88.3 0.6 1.1 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 RUS88299.1 - 0.0034 17.6 4.1 0.039 14.2 0.6 2.2 1 1 1 2 2 2 1 Homeobox associated leucine zipper KASH_CCD PF14662.6 RUS88299.1 - 0.0065 16.3 1.2 0.009 15.9 1.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Nse5 PF08691.10 RUS88299.1 - 0.0072 15.1 0.1 0.0088 14.8 0.1 1.1 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 bZIP_1 PF00170.21 RUS88299.1 - 0.013 15.6 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.12 RUS88299.1 - 0.044 14.2 2.1 0.055 13.9 2.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-HC5HC2H_2 PF13832.6 RUS88301.1 - 1.9e-29 102.0 8.0 1.9e-29 102.0 8.0 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RUS88301.1 - 1.4e-24 86.1 6.0 1.4e-24 86.1 6.0 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RUS88301.1 - 2.8e-12 46.0 5.0 2.8e-12 46.0 5.0 3.0 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 RUS88301.1 - 3.6e-09 36.4 8.5 3.6e-09 36.4 8.5 3.3 4 0 0 4 4 4 2 PHD-finger EPL1 PF10513.9 RUS88301.1 - 3.5e-07 30.8 3.1 3.5e-07 30.8 3.1 7.9 2 1 1 4 4 4 1 Enhancer of polycomb-like zf-PHD-like PF15446.6 RUS88301.1 - 0.0066 16.1 1.7 0.0066 16.1 1.7 4.1 4 1 0 4 4 4 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 RUS88301.1 - 3.3 7.7 18.8 0.073 13.0 1.0 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras PF00071.22 RUS88303.1 - 2.2e-54 183.4 0.9 2.6e-54 183.2 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS88303.1 - 1.7e-31 108.9 0.1 2.7e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS88303.1 - 4.6e-20 71.8 0.1 6.2e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS88303.1 - 1.6e-09 37.5 0.2 2e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 RUS88303.1 - 3.7e-07 29.8 0.0 6.8e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RUS88303.1 - 0.00037 20.6 0.0 0.00074 19.6 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 RUS88303.1 - 0.0068 16.3 0.6 0.011 15.7 0.1 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Ferrochelatase PF00762.19 RUS88303.1 - 0.019 14.1 0.2 0.026 13.6 0.2 1.2 1 0 0 1 1 1 0 Ferrochelatase CPT PF07931.12 RUS88303.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Ras PF00071.22 RUS88304.1 - 2.3e-50 170.4 1.7 2.8e-50 170.1 1.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS88304.1 - 1.4e-29 102.8 0.3 2.6e-29 101.9 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS88304.1 - 7.5e-16 58.1 0.1 1.2e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS88304.1 - 8e-06 25.4 0.2 3.9e-05 23.2 0.0 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RUS88304.1 - 0.00084 18.7 0.5 0.0011 18.4 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS88304.1 - 0.0037 17.3 0.1 0.0064 16.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Corazonin PF17308.2 RUS88304.1 - 0.011 16.1 0.1 0.02 15.2 0.1 1.4 1 1 0 1 1 1 0 Pro-corazonin AAA_14 PF13173.6 RUS88304.1 - 0.024 14.7 0.5 0.062 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 RUS88304.1 - 0.12 12.3 0.1 17 5.3 0.0 2.6 1 1 2 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 RUS88304.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ig PF00047.25 RUS88305.1 - 0.0025 18.0 1.0 0.0046 17.1 1.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 RUS88305.1 - 0.01 16.4 0.3 0.029 14.9 0.1 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Pkinase_Tyr PF07714.17 RUS88306.1 - 3.4e-91 305.1 0.0 5.1e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS88306.1 - 2e-35 122.4 0.0 1.1e-23 83.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 RUS88306.1 - 1.4e-29 102.0 0.1 2.1e-13 50.1 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS88306.1 - 4e-27 94.6 0.4 1.1e-12 48.4 0.0 6.0 5 0 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 RUS88306.1 - 3.7e-13 49.6 1.1 3.6e-07 30.4 0.0 4.5 5 0 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 RUS88306.1 - 1.3e-11 44.5 6.9 6e-08 32.7 0.0 5.7 6 1 0 6 6 6 1 Immunoglobulin domain V-set PF07686.17 RUS88306.1 - 2.6e-09 37.2 4.8 0.0026 17.9 0.0 5.9 5 2 0 5 5 5 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 RUS88306.1 - 0.00039 20.6 0.0 0.0033 17.6 0.0 2.4 2 0 0 2 2 2 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 RUS88306.1 - 0.012 15.6 0.0 1.6 8.8 0.0 3.4 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS88306.1 - 0.12 11.9 0.1 0.9 9.2 0.0 2.4 3 0 0 3 3 3 0 Immunoglobulin domain Ig_5 PF16681.5 RUS88306.1 - 0.25 11.8 0.9 16 6.0 0.1 3.6 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Wzy_C PF04932.15 RUS88306.1 - 2.2 7.9 4.2 4.7 6.8 4.2 1.4 1 0 0 1 1 1 0 O-Antigen ligase RFC1 PF08519.12 RUS88308.1 - 1.4e-59 200.7 0.0 4.5e-59 199.1 0.0 2.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 RUS88308.1 - 9.4e-16 58.0 0.0 3.7e-15 56.1 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 RUS88308.1 - 3.7e-14 53.3 0.2 1.7e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS88308.1 - 5.9e-06 26.6 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS88308.1 - 0.00015 22.2 0.0 0.00042 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 RUS88308.1 - 0.00041 20.3 0.1 0.011 15.6 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain BRCT_2 PF16589.5 RUS88308.1 - 0.0011 19.3 0.0 0.0048 17.3 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RuvB_N PF05496.12 RUS88308.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RUS88308.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 RUS88308.1 - 0.0081 16.0 1.2 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 RUS88308.1 - 0.0089 16.4 0.2 0.26 11.7 0.0 3.5 2 1 0 2 2 2 1 RNA helicase PTCB-BRCT PF12738.7 RUS88308.1 - 0.0096 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain AAA_5 PF07728.14 RUS88308.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RUS88308.1 - 0.047 14.2 0.6 0.56 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain LURAP PF14854.6 RUS88309.1 - 0.042 13.8 2.0 0.68 9.9 0.0 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein PsiF_repeat PF07769.14 RUS88309.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 psiF repeat Oxysterol_BP PF01237.18 RUS88311.1 - 1.6e-67 228.0 0.8 2.5e-67 227.3 0.8 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein RPOL_N PF14700.6 RUS88312.1 - 0.07 12.5 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal YlbD_coat PF14071.6 RUS88312.1 - 0.11 12.8 2.2 1.6 9.0 1.1 2.5 1 1 1 3 3 3 0 Putative coat protein MADF_DNA_bdg PF10545.9 RUS88313.1 - 1.3e-14 54.3 7.3 3.7e-13 49.6 7.5 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS88313.1 - 4.9e-10 39.0 0.1 1.6e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_4 PF13837.6 RUS88313.1 - 0.061 13.7 2.4 0.16 12.4 2.4 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.26 RUS88315.1 - 2.1e-27 94.0 32.0 8.4e-07 29.1 1.4 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88315.1 - 9.7e-22 75.8 30.8 2.8e-05 24.6 0.7 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS88315.1 - 1.4e-18 66.4 36.3 1.5e-07 31.5 0.5 5.7 5 2 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS88315.1 - 8.2e-14 51.5 7.8 0.0004 20.6 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS88315.1 - 1.1e-10 41.2 30.4 0.00054 19.9 0.5 5.7 5 1 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 RUS88315.1 - 3.1e-09 36.9 17.3 0.0015 18.8 0.3 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RUS88315.1 - 4.2e-06 26.4 31.6 0.057 13.2 0.6 5.2 5 0 0 5 5 5 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RUS88315.1 - 8.2e-06 25.8 20.1 0.04 14.0 2.4 4.3 2 2 1 3 3 3 2 Zinc ribbon domain zf-C2HE PF16278.5 RUS88315.1 - 1.5e-05 25.4 26.6 0.006 17.0 0.3 4.7 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 RUS88315.1 - 0.00022 21.2 12.9 2.9 8.0 0.5 5.1 5 0 0 5 5 5 2 XPA protein N-terminal zf-Di19 PF05605.12 RUS88315.1 - 0.0012 19.1 15.8 0.11 12.8 0.7 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 RUS88315.1 - 0.0055 16.7 14.8 1.7 8.7 0.5 3.4 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 RUS88315.1 - 0.0064 16.1 19.8 2.4 7.8 0.1 5.4 4 1 1 5 5 5 1 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 RUS88315.1 - 0.009 16.3 18.3 1.3 9.4 0.2 4.8 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 RUS88315.1 - 0.0092 16.0 0.4 0.0092 16.0 0.4 5.1 2 1 3 5 5 5 1 BED zinc finger zinc_ribbon_15 PF17032.5 RUS88315.1 - 0.016 16.0 0.3 0.016 16.0 0.3 3.1 2 1 1 3 3 3 0 zinc-ribbon family ADK_lid PF05191.14 RUS88315.1 - 0.018 15.1 14.0 3.5 7.7 0.1 4.2 3 2 2 5 5 5 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 RUS88315.1 - 0.032 14.1 23.7 0.37 10.7 0.2 5.0 5 0 0 5 5 4 0 zinc-finger of a C2HC-type DUF4764 PF15961.5 RUS88315.1 - 0.1 11.3 11.9 0.65 8.6 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) Sprouty PF05210.13 RUS88315.1 - 0.18 12.2 0.4 0.18 12.2 0.4 2.6 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-FPG_IleRS PF06827.14 RUS88315.1 - 0.22 11.4 10.2 9.9 6.1 0.3 4.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS YhfH PF14149.6 RUS88315.1 - 0.29 11.1 15.3 8.6 6.4 0.4 4.7 5 0 0 5 5 4 0 YhfH-like protein zf-AN1 PF01428.16 RUS88315.1 - 0.32 11.2 27.6 3.3 7.9 0.1 5.3 4 1 1 5 5 5 0 AN1-like Zinc finger zinc_ribbon_2 PF13240.6 RUS88315.1 - 0.4 10.4 17.1 7 6.5 0.2 4.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF2225 PF09986.9 RUS88315.1 - 0.6 9.8 5.6 3.1 7.4 1.4 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_Tnp_IS1595 PF12760.7 RUS88315.1 - 0.98 9.4 31.5 0.089 12.8 7.2 4.2 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 RUS88315.1 - 1.5 8.8 24.2 7.9 6.5 0.2 5.0 4 1 0 4 4 4 0 zinc-ribbon domain Actin_micro PF17003.5 RUS88315.1 - 1.6 7.8 7.3 41 3.2 7.3 2.5 1 1 0 1 1 1 0 Putative actin-like family zf-ribbon_3 PF13248.6 RUS88315.1 - 1.7 8.2 16.8 7.7 6.1 0.3 4.5 4 1 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 RUS88315.1 - 3.4 8.3 22.0 9.5 6.8 4.9 3.7 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain TFIIS_C PF01096.18 RUS88315.1 - 4 7.4 18.6 14 5.6 0.3 4.9 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) zinc_ribbon_10 PF10058.9 RUS88315.1 - 5 6.9 14.5 7.4 6.4 0.0 4.5 4 1 1 5 5 4 0 Predicted integral membrane zinc-ribbon metal-binding protein CutA1 PF03091.15 RUS88316.1 - 2.1e-38 130.2 0.0 2.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein MIP PF00230.20 RUS88317.1 - 1e-63 215.1 4.7 1.3e-63 214.8 4.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1772 PF08592.11 RUS88317.1 - 0.01 16.1 2.1 0.017 15.4 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4064 PF13273.6 RUS88317.1 - 0.043 14.1 1.2 0.043 14.1 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF5518 PF17647.1 RUS88317.1 - 0.69 10.1 16.8 1.5 9.0 5.7 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5518) Cupin_8 PF13621.6 RUS88318.1 - 0.00045 20.0 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Sulfotransfer_1 PF00685.27 RUS88320.1 - 8.5e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain SQS_PSY PF00494.19 RUS88321.1 - 1.1e-44 152.9 0.0 1.3e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Myosin_head PF00063.21 RUS88323.1 - 4.9e-05 21.8 0.0 7.4e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 RUS88323.1 - 0.0034 17.0 0.3 0.0071 16.1 0.3 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif DNA_pol_A_exoN PF18305.1 RUS88323.1 - 2.3 8.6 5.3 0.48 10.7 0.1 2.2 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain Sugar_tr PF00083.24 RUS88324.1 - 4.6e-31 108.2 28.0 3.7e-30 105.2 17.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS88324.1 - 7.3e-26 90.9 40.4 3.9e-22 78.7 25.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4231 PF14015.6 RUS88324.1 - 0.57 10.7 8.5 4.5 7.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) CUB PF00431.20 RUS88325.1 - 4e-35 120.5 2.1 1.1e-24 86.8 0.2 2.3 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.18 RUS88325.1 - 3.8e-07 30.2 6.9 1.2e-06 28.7 6.9 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Adeno_E3_CR2 PF02439.15 RUS88325.1 - 0.0049 16.6 1.8 0.008 15.9 1.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 IL6Ra-bind PF09240.10 RUS88325.1 - 0.035 14.5 0.3 0.12 12.8 0.3 1.8 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding EphA2_TM PF14575.6 RUS88325.1 - 0.073 14.0 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_64 PF16483.5 RUS88325.1 - 0.17 11.2 0.5 0.27 10.5 0.1 1.5 2 0 0 2 2 2 0 Beta-1,3-glucanase TMEM52 PF14979.6 RUS88325.1 - 2.6 7.9 9.2 0.44 10.5 4.2 2.2 2 1 1 3 3 3 0 Transmembrane 52 DUF3915 PF13054.6 RUS88326.1 - 0.0038 17.2 3.8 0.0045 17.0 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS88326.1 - 0.0078 14.6 8.4 0.0089 14.4 8.4 1.0 1 0 0 1 1 1 1 Atrophin-1 family DUF3824 PF12868.7 RUS88326.1 - 0.01 16.5 1.2 0.012 16.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) BES1_N PF05687.13 RUS88326.1 - 5.9 7.3 9.9 9.6 6.6 9.9 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal 2Fe-2S_thioredx PF01257.19 RUS88327.1 - 9.8e-58 194.1 0.1 1.3e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin CS PF04969.16 RUS88328.1 - 3.2e-15 56.9 0.0 1.9e-14 54.5 0.0 2.4 2 0 0 2 2 2 1 CS domain SNARE_assoc PF09335.11 RUS88329.1 - 9.2e-14 52.0 7.7 2e-13 50.9 7.7 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein MttA_Hcf106 PF02416.16 RUS88329.1 - 0.53 9.7 2.0 2.5 7.5 2.5 1.8 2 0 0 2 2 2 0 mttA/Hcf106 family HECT PF00632.25 RUS88330.1 - 6.9e-98 327.9 0.1 8.9e-98 327.5 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 RUS88330.1 - 7.9e-48 160.2 27.8 8.9e-14 51.3 2.5 5.0 5 0 0 5 5 5 4 WW domain C2 PF00168.30 RUS88330.1 - 1e-13 51.4 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain MBD PF01429.19 RUS88330.1 - 1.4 8.7 5.6 12 5.7 0.7 3.9 4 0 0 4 4 4 0 Methyl-CpG binding domain zf-H2C2_2 PF13465.6 RUS88331.1 - 1.6e-36 123.1 62.1 2.4e-08 34.0 2.0 9.5 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2 PF00096.26 RUS88331.1 - 1.3e-28 97.8 79.8 1.1e-05 25.6 2.0 9.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88331.1 - 1.2e-19 69.3 64.6 0.00056 20.5 0.9 8.9 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS88331.1 - 8.6e-13 47.8 82.0 1.5e-06 27.8 2.6 10.1 11 0 0 11 11 10 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RUS88331.1 - 1.5e-07 31.3 22.9 0.00037 20.4 2.7 7.6 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS88331.1 - 9.2e-06 25.8 37.3 0.47 10.8 0.2 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RUS88331.1 - 0.0019 17.7 14.4 0.73 9.5 0.2 5.7 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 RUS88331.1 - 0.012 16.0 1.7 0.012 16.0 1.7 7.9 8 1 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RUS88331.1 - 0.061 13.8 47.5 0.2 12.1 1.1 8.6 2 2 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger TC1 PF15063.6 RUS88331.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Thyroid cancer protein 1 zf-C2H2_11 PF16622.5 RUS88331.1 - 0.09 12.6 0.2 0.09 12.6 0.2 7.4 7 0 0 7 7 7 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 RUS88331.1 - 1.2 9.5 14.6 1.9 8.8 0.4 5.2 5 0 0 5 5 5 0 zinc-ribbon GAGA PF09237.11 RUS88331.1 - 2.9 7.8 17.3 1.6 8.6 0.1 4.8 2 2 4 6 6 6 0 GAGA factor zf-C2H2_7 PF15269.6 RUS88331.1 - 5.7 7.1 46.0 0.67 10.1 2.2 7.0 3 2 4 7 7 7 0 Zinc-finger TPX2_importin PF12214.8 RUS88332.1 - 9.7e-25 87.7 53.2 1.9e-14 54.2 2.4 6.2 3 2 2 5 5 5 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 RUS88332.1 - 2.8e-09 37.1 8.9 2.8e-09 37.1 8.9 5.3 5 0 0 5 5 5 2 Targeting protein for Xklp2 (TPX2) Aurora-A_bind PF09041.10 RUS88332.1 - 0.0043 17.1 0.2 0.011 15.8 0.2 1.7 1 0 0 1 1 1 1 Aurora-A binding DUF853 PF05872.12 RUS88332.1 - 0.019 13.6 2.2 0.051 12.2 2.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) zf-H2C2_2 PF13465.6 RUS88333.1 - 6.7e-21 73.7 75.0 5.3e-07 29.8 0.6 11.1 11 0 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS88333.1 - 2.7e-14 52.6 67.9 1.6e-05 24.6 2.0 8.2 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RUS88333.1 - 2.6e-10 40.1 98.5 0.0011 19.3 0.5 11.4 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88333.1 - 1.6e-09 37.8 87.6 0.015 16.0 0.3 11.5 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_7 PF15269.6 RUS88333.1 - 0.017 15.2 2.7 0.017 15.2 2.7 5.0 3 1 1 4 4 4 0 Zinc-finger zf-C2H2_jaz PF12171.8 RUS88333.1 - 0.3 11.4 0.1 0.3 11.4 0.1 7.1 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 RUS88333.1 - 1.4 8.8 12.7 13 5.6 0.1 5.0 5 1 0 5 5 5 0 GAGA factor GCIP PF13324.6 RUS88334.1 - 4.4e-46 157.6 2.4 5.4e-46 157.3 2.4 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DEAD PF00270.29 RUS88335.1 - 3.2e-18 66.1 0.1 6.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TUDOR PF00567.24 RUS88335.1 - 1.3e-15 57.5 0.0 4.4e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.31 RUS88335.1 - 0.016 15.5 0.0 0.077 13.3 0.0 2.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PilP PF04351.13 RUS88335.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP EcpB_C PF18649.1 RUS88335.1 - 0.069 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 EcpB C-terminal domain TUDOR PF00567.24 RUS88336.1 - 1.2e-24 86.7 0.1 1.8e-19 70.0 0.0 2.7 2 0 0 2 2 2 2 Tudor domain CS PF04969.16 RUS88336.1 - 0.0014 19.6 0.7 0.0048 17.9 0.4 2.2 2 0 0 2 2 2 1 CS domain Arm PF00514.23 RUS88336.1 - 0.04 14.0 0.1 0.21 11.7 0.1 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat zf-H2C2_2 PF13465.6 RUS88337.1 - 1.3e-46 155.0 74.3 2.9e-08 33.8 4.6 10.3 10 0 0 10 10 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 RUS88337.1 - 4.9e-30 102.3 82.7 0.00028 21.2 1.4 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88337.1 - 1.2e-23 81.7 75.5 0.012 16.4 1.3 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS88337.1 - 5e-20 70.9 67.6 2.8e-06 27.0 0.1 9.6 9 1 0 9 9 9 4 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS88337.1 - 4.6e-07 30.0 54.0 0.0062 16.8 0.5 9.9 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 RUS88337.1 - 0.00062 19.5 13.5 0.17 11.7 0.8 4.4 1 1 4 5 5 5 4 GAGA factor zf-met PF12874.7 RUS88337.1 - 0.0038 17.6 44.2 0.13 12.7 0.8 8.3 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 RUS88337.1 - 0.0098 16.6 32.9 1.4 9.8 0.4 5.3 3 2 2 5 5 5 3 zinc-ribbon family zf-C2H2_6 PF13912.6 RUS88337.1 - 0.02 14.9 2.2 0.02 14.9 2.2 9.2 11 1 0 11 11 11 0 C2H2-type zinc finger DUF5549 PF17703.1 RUS88337.1 - 0.27 10.9 1.9 1 9.0 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5549) zf_ZIC PF18366.1 RUS88337.1 - 0.38 10.9 5.4 1.3 9.1 0.3 2.8 1 1 1 2 2 2 0 Zic proteins zinc finger domain DUF2719 PF10891.8 RUS88337.1 - 0.42 10.6 3.4 4.6 7.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) zf_C2H2_10 PF18414.1 RUS88337.1 - 1.9 8.1 7.7 2.6 7.7 0.4 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-C2H2_2 PF12756.7 RUS88337.1 - 3.2 8.2 47.5 0.092 13.1 4.0 7.2 1 1 6 7 7 6 0 C2H2 type zinc-finger (2 copies) MFS_1 PF07690.16 RUS88339.1 - 9.1e-54 182.7 20.4 6.6e-52 176.6 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS88339.1 - 4.1e-09 35.8 18.6 3.8e-08 32.6 18.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PT PF04886.12 RUS88340.1 - 3.1e-36 122.6 125.0 1.7e-12 46.7 27.1 5.1 2 1 0 2 2 2 1 PT repeat DUF148 PF02520.17 RUS88341.1 - 0.00071 19.6 8.0 5.3 7.2 0.1 3.9 1 1 3 4 4 4 4 Domain of unknown function DUF148 DASH_Dad2 PF08654.10 RUS88341.1 - 0.076 13.4 23.6 20 5.7 1.7 5.9 1 1 5 6 6 6 0 DASH complex subunit Dad2 F420_ligase PF01996.16 RUS88341.1 - 0.2 10.9 2.9 5.1 6.4 2.9 2.2 1 1 0 1 1 1 0 F420-0:Gamma-glutamyl ligase FUN14 PF04930.15 RUS88341.1 - 0.29 11.6 10.0 42 4.7 2.2 4.4 1 1 1 2 2 2 0 FUN14 family AbrB_C PF18277.1 RUS88341.1 - 0.54 9.9 6.6 3.4e+02 1.0 0.1 5.8 6 0 0 6 6 6 0 AbrB C-terminal domain Dynactin_p22 PF07426.11 RUS88341.1 - 3.7 7.4 7.3 31 4.4 0.2 3.4 1 1 2 4 4 4 0 Dynactin subunit p22 Epiglycanin_TR PF05647.11 RUS88341.1 - 7.3 6.6 23.0 4.1 7.4 5.0 3.6 1 1 2 3 3 3 0 Tandem-repeating region of mucin, epiglycanin-like SbmA_BacA PF05992.12 RUS88341.1 - 10 5.5 23.7 12 5.2 0.6 4.5 1 1 2 4 4 4 0 SbmA/BacA-like family Peptidase_S9 PF00326.21 RUS88342.1 - 2e-46 158.1 0.0 5.7e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 RUS88342.1 - 9.1e-07 28.6 0.1 2.9e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 RUS88342.1 - 0.00078 19.1 0.0 0.84 9.2 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 RUS88342.1 - 0.0013 18.0 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 RUS88342.1 - 0.038 14.0 0.1 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AXE1 PF05448.12 RUS88342.1 - 0.039 12.6 0.0 1.1 7.8 0.0 2.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 RUS88342.1 - 0.091 12.6 0.0 3.4 7.5 0.0 2.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF5050 PF16472.5 RUS88342.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) Abhydrolase_6 PF12697.7 RUS88342.1 - 0.12 12.9 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M13_N PF05649.13 RUS88343.1 - 6.6e-75 253.2 1.7 1e-74 252.6 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS88343.1 - 6.2e-68 228.4 0.5 1e-67 227.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 DUF2045 PF09741.9 RUS88343.1 - 0.052 12.9 0.4 4.9 6.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2045) DUF2004 PF09406.10 RUS88343.1 - 0.074 13.4 1.0 0.22 11.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Pex14_N PF04695.13 RUS88344.1 - 4.3 8.0 10.2 8.1 7.1 10.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CBM_14 PF01607.24 RUS88345.1 - 1.7e-28 98.6 23.3 1.1e-08 35.1 1.5 4.4 4 0 0 4 4 4 4 Chitin binding Peritrophin-A domain SEA PF01390.20 RUS88345.1 - 2.8e-06 27.4 0.2 2.8e-06 27.4 0.2 2.2 2 0 0 2 2 2 1 SEA domain Calc_CGRP_IAPP PF00214.19 RUS88345.1 - 0.13 12.7 0.2 0.34 11.3 0.2 1.7 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family T4_deiodinase PF00837.17 RUS88345.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase CBM_19 PF03427.13 RUS88345.1 - 0.19 11.8 4.4 45 4.1 0.0 3.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) MAP70 PF07058.11 RUS88345.1 - 1 8.0 10.0 1.6 7.3 10.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 Macoilin PF09726.9 RUS88345.1 - 3 6.3 10.2 5.8 5.3 10.2 1.4 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 RUS88345.1 - 5.7 5.2 12.8 10 4.4 12.8 1.3 1 0 0 1 1 1 0 Menin SEA PF01390.20 RUS88346.1 - 1.6e-08 34.6 0.5 3.1e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 SEA domain ASC PF00858.24 RUS88347.1 - 1e-57 196.1 4.4 1.8e-49 168.9 4.2 2.2 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel SEA PF01390.20 RUS88348.1 - 1.6e-28 98.9 0.1 2.9e-08 33.7 0.0 4.3 4 0 0 4 4 4 4 SEA domain BPD_transp_2 PF02653.16 RUS88349.1 - 0.021 14.0 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Orf78 PF06024.12 RUS88349.1 - 0.029 14.7 0.3 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF2207 PF09972.9 RUS88349.1 - 0.048 12.4 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 RUS88349.1 - 6.4 6.7 7.8 0.45 10.4 2.6 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Galactosyl_T PF01762.21 RUS88350.1 - 1.7e-37 129.1 0.1 2.2e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase TRAP-delta PF05404.12 RUS88351.1 - 2.8e-61 205.8 0.0 3.4e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) An_peroxidase PF03098.15 RUS88352.1 - 2.4e-115 386.1 0.0 2.9e-115 385.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase WASH-7_N PF14745.6 RUS88353.1 - 8.2e-226 751.0 6.6 8.2e-226 751.0 6.6 2.3 2 0 0 2 2 2 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 RUS88353.1 - 7.2e-170 564.6 6.7 7.2e-170 564.6 6.7 1.8 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.6 RUS88353.1 - 6.9e-74 247.3 5.9 1.5e-73 246.2 5.9 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal YsaB PF13983.6 RUS88353.1 - 0.099 12.9 0.3 0.26 11.6 0.3 1.7 1 0 0 1 1 1 0 YsaB-like lipoprotein MSA-2c PF12238.8 RUS88353.1 - 0.2 11.6 2.5 0.49 10.4 2.5 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4598 PF15370.6 RUS88354.1 - 8.1e-08 32.7 7.5 8.1e-08 32.7 7.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) BUD22 PF09073.10 RUS88354.1 - 0.39 10.0 12.2 0.45 9.8 12.2 1.1 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 RUS88354.1 - 0.75 10.1 12.0 0.1 12.8 3.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DSPc PF00782.20 RUS88355.1 - 1.1e-43 148.2 0.1 2.1e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RUS88355.1 - 4.9e-10 39.9 0.0 1.6e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RUS88355.1 - 0.00029 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RUS88355.1 - 0.01 16.1 0.0 0.031 14.6 0.0 1.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 RUS88355.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3313 PF11769.8 RUS88357.1 - 0.011 15.6 4.3 12 5.7 4.3 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) DUF3819 PF12842.7 RUS88357.1 - 0.084 12.8 5.3 30 4.5 5.3 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) Trigger_C PF05698.14 RUS88357.1 - 0.13 12.3 2.2 0.66 10.0 2.2 2.2 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus HI0933_like PF03486.14 RUS88357.1 - 0.3 9.7 5.6 0.5 9.0 5.7 1.4 1 1 0 1 1 1 0 HI0933-like protein JHBP PF06585.11 RUS88357.1 - 0.56 9.3 16.4 1.7 7.8 5.5 2.0 1 1 1 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) DUF3510 PF12022.8 RUS88357.1 - 4.3 7.7 10.9 5.2e+02 1.0 10.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) ThiF PF00899.21 RUS88358.1 - 5.6e-63 212.6 0.0 8e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 RUS88358.1 - 6.9e-25 87.0 1.3 1e-24 86.4 1.3 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 RUS88358.1 - 0.0031 18.1 0.2 0.0063 17.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 RUS88358.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RUS88358.1 - 0.069 13.7 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 RUS88359.1 - 6.2e-06 26.0 1.8 7.7e-06 25.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like PI31_Prot_N PF11566.8 RUS88359.1 - 0.0003 20.6 0.0 0.00083 19.2 0.0 1.8 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal UN_NPL4 PF11543.8 RUS88359.1 - 0.00051 20.5 0.1 0.001 19.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 F-box_4 PF15966.5 RUS88359.1 - 0.00084 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 RUS88359.1 - 0.0098 15.8 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain PB1 PF00564.24 RUS88359.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 PB1 domain HSP70 PF00012.20 RUS88360.1 - 2.2e-98 330.0 0.0 2.5e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS88360.1 - 4.2e-05 22.5 0.0 9.8e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 RUS88360.1 - 0.0014 18.4 0.3 0.0055 16.5 0.0 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain AnmK PF03702.14 RUS88360.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Cyt-b5 PF00173.28 RUS88361.1 - 1.2e-09 38.2 0.4 2.3e-09 37.2 0.4 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidohydro_3 PF07969.11 RUS88362.1 - 5.2e-16 59.2 5.3 4.1e-09 36.4 0.3 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 RUS88362.1 - 4.6e-12 45.9 3.0 3.1e-11 43.2 3.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family DLP_helical PF18709.1 RUS88364.1 - 0.047 12.9 1.5 0.72 9.0 0.1 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain CENP-H PF05837.12 RUS88364.1 - 0.071 13.5 2.6 4.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) OmpH PF03938.14 RUS88364.1 - 0.43 10.9 4.7 0.69 10.3 2.2 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ion_trans PF00520.31 RUS88366.1 - 5e-40 137.3 10.2 6.5e-40 136.9 10.2 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS88366.1 - 2.5e-23 82.2 0.0 4.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS88366.1 - 8.9e-13 48.0 3.8 8.9e-13 48.0 3.8 2.3 2 0 0 2 2 2 1 Ion channel Phage_holin_7_1 PF16081.5 RUS88368.1 - 0.028 14.6 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Phage_holin_3_6 PF07332.11 RUS88368.1 - 0.053 13.6 3.6 0.07 13.2 3.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EphA2_TM PF14575.6 RUS88368.1 - 1.5 9.8 4.6 1.2 10.1 1.2 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 RUS88371.1 - 0.00014 22.0 43.7 0.00019 21.6 43.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SMN PF06003.12 RUS88371.1 - 0.088 12.0 6.0 0.13 11.5 6.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) V_ATPase_I PF01496.19 RUS88371.1 - 0.19 9.6 20.5 0.22 9.4 20.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRAT PF04970.13 RUS88371.1 - 0.21 11.9 11.4 0.24 11.7 0.0 2.4 1 1 1 2 2 2 0 Lecithin retinol acyltransferase CDC45 PF02724.14 RUS88371.1 - 0.26 9.5 18.2 0.31 9.3 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein XRN_M PF17846.1 RUS88371.1 - 0.28 10.1 16.9 0.36 9.7 16.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain GAGA_bind PF06217.12 RUS88371.1 - 0.33 11.2 19.8 0.44 10.8 19.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Dapper PF15268.6 RUS88371.1 - 0.64 8.8 28.8 0.74 8.6 28.8 1.0 1 0 0 1 1 1 0 Dapper Gti1_Pac2 PF09729.9 RUS88371.1 - 0.69 10.0 22.2 1.2 9.1 22.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Tim54 PF11711.8 RUS88371.1 - 0.8 8.4 17.5 1.2 7.8 17.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 RUS88371.1 - 0.81 7.9 41.0 1 7.5 41.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRP-alpha_N PF04086.13 RUS88371.1 - 1 9.2 23.4 1.3 8.9 23.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2252 PF10009.9 RUS88371.1 - 1.3 8.0 13.7 1.6 7.7 13.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) RR_TM4-6 PF06459.12 RUS88371.1 - 1.4 8.6 24.5 2.4 7.9 24.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 RUS88371.1 - 1.5 5.8 23.8 1.9 5.5 23.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VIT1 PF01988.19 RUS88371.1 - 2.4 8.0 8.2 3.2 7.6 8.2 1.4 1 0 0 1 1 1 0 VIT family MMR1 PF08505.10 RUS88371.1 - 2.5 8.3 28.7 3.7 7.8 28.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF966 PF06136.13 RUS88371.1 - 3.2 7.4 19.6 4 7.1 19.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ABC2_membrane_2 PF12679.7 RUS88371.1 - 4.7 6.4 7.5 9.9 5.3 7.5 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2828 PF11443.8 RUS88371.1 - 4.8 5.1 21.8 6.1 4.8 21.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF-3_zeta PF05091.12 RUS88371.1 - 5.3 5.9 27.7 8.2 5.3 27.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3492 PF11997.8 RUS88371.1 - 5.8 6.6 13.2 8.5 6.0 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Asp-B-Hydro_N PF05279.11 RUS88371.1 - 6.1 6.8 22.5 8.2 6.4 22.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MAT1 PF06391.13 RUS88371.1 - 8.6 6.1 41.9 12 5.6 41.9 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Glyco_hydro_31 PF01055.26 RUS88372.1 - 2.9e-30 105.9 0.0 3e-29 102.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4381 PF14316.6 RUS88373.1 - 2.7 8.2 0.0 2.7 8.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) SPC25 PF06703.11 RUS88373.1 - 6.9 6.4 11.4 0.1 12.4 1.6 2.4 2 1 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Somatomedin_B PF01033.17 RUS88375.1 - 9e-08 32.4 7.9 2.6e-07 30.9 7.9 1.8 1 0 0 1 1 1 1 Somatomedin B domain DUF5109 PF17134.4 RUS88375.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) Dpy19 PF10034.9 RUS88376.1 - 1.2e-208 694.4 9.0 1.4e-208 694.2 9.0 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation PTN_MK_C PF01091.18 RUS88377.1 - 2.1e-09 37.6 19.5 8.2e-06 26.1 3.0 3.2 1 1 1 2 2 2 2 PTN/MK heparin-binding protein family, C-terminal domain DUF1826 PF08856.11 RUS88377.1 - 0.0046 16.9 0.3 0.0084 16.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1826) Nop14 PF04147.12 RUS88378.1 - 7.4e-05 21.2 9.7 7.4e-05 21.2 9.7 1.9 2 0 0 2 2 2 1 Nop14-like family DNA_pol_phi PF04931.13 RUS88378.1 - 0.0025 16.0 31.6 0.0048 15.1 31.6 1.4 1 0 0 1 1 1 1 DNA polymerase phi RPA43_OB PF17875.1 RUS88378.1 - 0.0047 17.6 1.4 0.016 15.8 0.0 2.5 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I BUD22 PF09073.10 RUS88378.1 - 0.0056 16.1 6.2 0.0056 16.1 6.2 2.3 2 1 0 2 2 2 1 BUD22 YL1 PF05764.13 RUS88378.1 - 0.0077 16.4 10.8 0.0077 16.4 10.8 2.3 2 0 0 2 2 2 1 YL1 nuclear protein RRN3 PF05327.11 RUS88378.1 - 1.4 7.4 22.3 0.01 14.4 14.2 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Pex14_N PF04695.13 RUS88379.1 - 0.094 13.4 0.1 0.094 13.4 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2570 PF10828.8 RUS88379.1 - 0.15 11.9 0.6 0.5 10.2 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Arg_decarbox_C PF17944.1 RUS88379.1 - 1.3 9.7 5.2 3.3 8.4 0.3 3.3 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Exo_endo_phos PF03372.23 RUS88380.1 - 2.7e-23 82.7 0.0 3.2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RUS88380.1 - 0.00018 21.4 0.0 0.00066 19.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Tim54 PF11711.8 RUS88380.1 - 0.51 9.1 5.6 0.69 8.6 5.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.16 RUS88380.1 - 5.8 6.4 8.8 10 5.6 5.8 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 zf-Tim10_DDP PF02953.15 RUS88381.1 - 1.1e-26 92.3 3.5 1.6e-26 91.7 3.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.17 RUS88381.1 - 0.0095 16.2 0.6 0.014 15.7 0.6 1.2 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain NES_C_h PF18208.1 RUS88381.1 - 0.029 14.6 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain SRI PF08236.11 RUS88381.1 - 0.07 13.3 0.1 0.1 12.8 0.1 1.3 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Antistasin PF02822.14 RUS88382.1 - 5.1e-07 30.2 30.1 0.00015 22.3 10.5 5.5 5 1 0 5 5 5 3 Antistasin family Sec23_trunk PF04811.15 RUS88383.1 - 1.4e-08 34.6 0.1 3.4e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.6 RUS88383.1 - 1.3e-05 25.8 1.6 0.0076 16.9 1.0 4.0 2 1 0 2 2 2 1 von Willebrand factor type A domain Sec23_BS PF08033.12 RUS88383.1 - 0.00017 22.2 0.0 0.00039 21.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RUS88383.1 - 0.00052 20.0 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.7 RUS88383.1 - 0.14 12.1 0.4 0.28 11.2 0.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Arm PF00514.23 RUS88384.1 - 1.9e-86 281.8 17.5 6.8e-13 48.2 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RUS88384.1 - 4.1e-25 87.1 2.3 6.7e-25 86.4 0.9 2.1 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 RUS88384.1 - 1.7e-24 86.1 0.4 3.1e-24 85.2 0.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 RUS88384.1 - 5.5e-24 84.2 4.1 6.6e-06 26.5 0.0 6.3 6 0 0 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 RUS88384.1 - 2.1e-21 76.1 0.0 7.6e-06 26.2 0.0 5.2 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 RUS88384.1 - 1.1e-17 62.6 8.3 0.014 15.6 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat RICTOR_V PF14668.6 RUS88384.1 - 1.8e-06 28.1 0.4 0.36 11.1 0.0 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 RUS88384.1 - 2.5e-06 26.3 0.1 0.14 10.7 0.0 3.3 1 1 0 3 3 3 2 Adaptin N terminal region HEAT_PBS PF03130.16 RUS88384.1 - 8.9e-06 25.9 0.1 4.4 8.2 0.0 4.9 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat Arm_2 PF04826.13 RUS88384.1 - 8.5e-05 22.1 0.1 0.0086 15.6 0.1 3.0 3 1 1 4 4 4 2 Armadillo-like Cnd1 PF12717.7 RUS88384.1 - 0.00035 20.7 0.0 3.8 7.5 0.0 4.0 1 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 RUS88384.1 - 0.00058 20.0 0.1 0.23 11.6 0.1 3.3 3 1 1 4 4 4 2 V-ATPase subunit H NopRA1 PF16201.5 RUS88384.1 - 0.0049 16.5 0.1 6.5 6.3 0.0 3.8 2 2 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 CTNNBL PF08216.11 RUS88384.1 - 0.048 13.8 0.1 2.9 8.1 0.0 3.8 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear RasGEF_N_2 PF14663.6 RUS88384.1 - 0.14 12.5 2.0 2.3 8.7 0.2 3.6 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 RUS88384.1 - 0.15 11.6 0.2 0.35 10.4 0.2 1.7 1 0 0 1 1 1 0 CLASP N terminal DUF3361 PF11841.8 RUS88384.1 - 0.24 11.3 1.0 13 5.7 0.2 3.1 3 2 0 3 3 3 0 Domain of unknown function (DUF3361) DEAD PF00270.29 RUS88385.1 - 8.9e-45 152.6 1.3 1.8e-44 151.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS88385.1 - 2.9e-27 95.2 0.1 1.1e-25 90.2 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RUS88385.1 - 3.7e-10 39.9 0.1 9.6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 RUS88385.1 - 0.0017 17.6 0.1 0.0017 17.6 0.1 2.5 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase Neuropeptide_S PF14993.6 RUS88385.1 - 0.22 11.3 1.2 7.6 6.4 0.0 3.6 4 0 0 4 4 4 0 Neuropeptide S precursor protein CN_hydrolase PF00795.22 RUS88386.1 - 5.8e-37 127.4 0.0 8.9e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RUS88386.1 - 7e-26 90.8 0.0 1.5e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Ndc80_HEC PF03801.13 RUS88387.1 - 5.2e-39 133.3 0.0 5.2e-39 133.3 0.0 2.4 3 1 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 RUS88387.1 - 6.4e-10 39.0 1.7 6.4e-10 39.0 1.7 6.8 5 3 2 7 7 7 1 Domain of unknown function (DUF5595) DUF4780 PF16012.5 RUS88387.1 - 0.0011 18.5 0.0 0.0035 16.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4780) HALZ PF02183.18 RUS88387.1 - 0.043 14.0 0.4 0.043 14.0 0.4 4.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper NAT PF04768.13 RUS88387.1 - 1.1 8.9 11.6 3.4 7.3 1.6 3.1 2 1 1 3 3 3 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Ost5 PF05251.12 RUS88388.1 - 5.8e-31 106.6 6.7 6.4e-31 106.4 6.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 RUS88388.1 - 0.014 15.5 1.4 0.014 15.5 1.4 1.4 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III EptA_B_N PF08019.12 RUS88388.1 - 0.016 15.1 3.1 0.018 14.9 3.1 1.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF485 PF04341.12 RUS88388.1 - 0.18 11.8 7.6 0.24 11.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 CbtB PF09489.10 RUS88388.1 - 1.1 9.4 4.0 16 5.7 0.2 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) SSPI PF14098.6 RUS88388.1 - 1.4 9.1 8.3 5.2 7.3 0.3 2.1 1 1 1 2 2 2 0 Small, acid-soluble spore protein I EF-hand_7 PF13499.6 RUS88391.1 - 1.1e-08 35.3 7.6 0.00026 21.4 0.1 4.0 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 RUS88391.1 - 5.2e-06 26.0 4.3 0.52 10.4 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain DUF3053 PF11254.8 RUS88391.1 - 0.0022 17.6 1.8 0.0039 16.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) EF-hand_1 PF00036.32 RUS88391.1 - 9.3 6.1 9.2 18 5.1 0.1 4.4 6 0 0 6 6 6 0 EF hand Methyltransf_25 PF13649.6 RUS88392.1 - 1.4e-17 64.2 0.0 3.7e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS88392.1 - 9e-17 61.5 0.0 1.5e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS88392.1 - 2e-12 47.7 0.0 3.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS88392.1 - 5e-10 39.4 0.0 6.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS88392.1 - 5.1e-09 36.2 0.0 8.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS88392.1 - 8.4e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 RUS88392.1 - 0.00026 20.2 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MTS PF05175.14 RUS88392.1 - 0.014 15.0 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 RUS88392.1 - 0.02 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 RUS88392.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 RUS88392.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DZF PF07528.14 RUS88393.1 - 7e-94 314.1 0.0 8.9e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 RUS88393.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Mt_ATP-synt_B PF05405.14 RUS88394.1 - 1e-27 96.8 5.8 1e-27 96.8 5.8 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PIN_8 PF18476.1 RUS88394.1 - 0.014 15.2 5.6 0.022 14.6 5.6 1.1 1 0 0 1 1 1 0 PIN like domain DUF716 PF04819.12 RUS88396.1 - 1.1e-17 64.0 5.7 2.2e-17 63.0 5.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF716) DUF575 PF04746.12 RUS88396.1 - 0.068 13.4 0.0 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) DUF716 PF04819.12 RUS88397.1 - 4.1e-15 55.6 0.6 8.7e-15 54.6 0.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) Acyltransferase PF01553.21 RUS88397.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 1 1 0 1 1 1 0 Acyltransferase MARVEL PF01284.23 RUS88397.1 - 2.5 8.1 6.5 3.1 7.8 1.3 2.3 1 1 1 2 2 2 0 Membrane-associating domain COesterase PF00135.28 RUS88399.1 - 6.6e-107 358.5 0.0 7.3e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS88399.1 - 1.6e-10 41.2 0.1 4.3e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS88399.1 - 0.045 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 RUS88400.1 - 5.2e-119 398.4 0.0 9.9e-76 255.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS88400.1 - 4.2e-10 39.8 0.0 9.2e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF716 PF04819.12 RUS88401.1 - 2.3e-19 69.4 10.2 2.3e-19 69.4 10.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF716) HLH PF00010.26 RUS88402.1 - 2.3e-14 53.1 6.2 3.9e-14 52.4 6.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SPX PF03105.19 RUS88403.1 - 1.9 8.3 13.8 2.5 8.0 13.8 1.2 1 0 0 1 1 1 0 SPX domain Phage_Gp19 PF09355.10 RUS88403.1 - 3.2 8.2 3.9 10 6.6 0.4 2.3 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 AAA_11 PF13086.6 RUS88405.1 - 2e-53 181.9 0.8 2e-53 181.9 0.8 6.1 5 2 1 6 6 6 1 AAA domain AAA_12 PF13087.6 RUS88405.1 - 3.9e-47 160.4 0.8 1.4e-46 158.6 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS88405.1 - 1.5e-10 41.2 0.0 8.2e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RUS88405.1 - 1.9e-09 38.0 0.1 1.5e-08 35.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.14 RUS88405.1 - 0.00076 18.7 0.0 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase Helicase_RecD PF05127.14 RUS88405.1 - 0.0011 18.9 0.1 0.0058 16.5 0.0 2.3 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 RUS88405.1 - 0.0012 18.9 0.0 0.0012 18.9 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RUS88405.1 - 0.0076 15.7 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 RUS88405.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Anoctamin PF04547.12 RUS88406.1 - 6.4e-158 526.3 14.1 8.4e-158 525.9 14.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 RUS88406.1 - 4e-70 236.1 0.2 6.8e-70 235.3 0.2 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2417 PF10329.9 RUS88406.1 - 3.5e-06 26.6 2.8 0.0006 19.3 0.0 3.2 2 1 1 3 3 3 2 Region of unknown function (DUF2417) Rer1 PF03248.13 RUS88406.1 - 0.042 13.6 0.1 0.042 13.6 0.1 3.0 2 1 0 2 2 2 0 Rer1 family Peptidase_M13_N PF05649.13 RUS88407.1 - 6.4e-89 299.3 0.0 8.5e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS88407.1 - 1.4e-51 175.0 0.0 2.4e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 ImmE5 PF11480.8 RUS88407.1 - 0.0059 17.1 0.1 1.5 9.3 0.0 2.9 2 0 0 2 2 2 1 Colicin-E5 Imm protein Peptidase_M48 PF01435.18 RUS88407.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 bZIP_2 PF07716.15 RUS88408.1 - 0.00066 19.7 13.0 0.0021 18.1 12.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS88408.1 - 0.017 15.6 3.2 0.041 14.4 3.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 RUS88408.1 - 0.088 12.9 14.8 0.2 11.8 14.8 1.6 1 0 0 1 1 1 0 bZIP transcription factor V_ATPase_I PF01496.19 RUS88409.1 - 6e-07 27.8 7.9 7.3e-07 27.5 7.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 RUS88409.1 - 6.1e-07 28.2 3.4 7e-07 28.0 3.4 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Shisa PF13908.6 RUS88409.1 - 2.4e-06 27.9 2.2 2.4e-06 27.9 1.4 1.3 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.16 RUS88409.1 - 7.3e-06 26.2 2.9 1.1e-05 25.7 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 RUS88409.1 - 8.1e-06 25.8 7.2 1.3e-05 25.1 7.2 1.3 1 0 0 1 1 1 1 Connexin SpoIIIAH PF12685.7 RUS88409.1 - 1.2e-05 25.3 5.0 1.7e-05 24.8 5.0 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein CBP_BcsG PF11658.8 RUS88409.1 - 1.7e-05 23.4 2.4 2.3e-05 23.0 2.4 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG MAP17 PF15807.5 RUS88409.1 - 1.9e-05 24.9 8.2 3.3e-05 24.1 8.2 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EMC3_TMCO1 PF01956.16 RUS88409.1 - 4.5e-05 23.2 13.5 6.8e-05 22.7 13.5 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like FAM176 PF14851.6 RUS88409.1 - 5.5e-05 22.9 0.3 0.00011 21.9 0.3 1.5 1 0 0 1 1 1 1 FAM176 family 7tm_1 PF00001.21 RUS88409.1 - 6.2e-05 22.4 0.6 7.1e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RNA_pol_Rpc4 PF05132.14 RUS88409.1 - 0.00011 22.6 2.9 0.00015 22.3 2.9 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 SARAF PF06682.12 RUS88409.1 - 0.00028 20.7 0.1 0.00039 20.2 0.1 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Protocadherin PF08374.11 RUS88409.1 - 0.0003 20.8 18.3 0.00031 20.8 17.3 1.4 2 0 0 2 2 1 1 Protocadherin CLN3 PF02487.17 RUS88409.1 - 0.00037 19.7 3.5 0.00052 19.2 3.5 1.2 1 0 0 1 1 1 1 CLN3 protein Serinc PF03348.15 RUS88409.1 - 0.0004 19.4 0.6 0.00045 19.3 0.6 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Amnionless PF14828.6 RUS88409.1 - 0.00057 18.8 0.1 0.00074 18.5 0.1 1.1 1 0 0 1 1 1 1 Amnionless DDHD PF02862.17 RUS88409.1 - 0.00079 19.6 1.1 0.00079 19.6 1.1 1.2 1 0 0 1 1 1 1 DDHD domain RIFIN PF02009.16 RUS88409.1 - 0.00084 19.3 17.7 0.00084 19.3 17.7 2.3 1 1 1 2 2 1 1 Rifin FHIPEP PF00771.20 RUS88409.1 - 0.00089 17.9 0.3 0.0013 17.3 0.3 1.3 1 0 0 1 1 1 1 FHIPEP family DUF2852 PF11014.8 RUS88409.1 - 0.00095 19.3 0.2 0.0015 18.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) EOS1 PF12326.8 RUS88409.1 - 0.0017 18.3 3.8 0.003 17.5 3.8 1.5 1 0 0 1 1 1 1 N-glycosylation protein DUF4692 PF15763.5 RUS88409.1 - 0.0019 18.7 0.2 0.0028 18.1 0.2 1.2 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) DUF4834 PF16118.5 RUS88409.1 - 0.002 19.0 29.1 0.012 16.6 29.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) Myc_target_1 PF15179.6 RUS88409.1 - 0.0034 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Myc target protein 1 DUF3328 PF11807.8 RUS88409.1 - 0.0035 17.1 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4446 PF14584.6 RUS88409.1 - 0.0039 17.2 16.9 0.0064 16.5 16.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) CitMHS PF03600.16 RUS88409.1 - 0.0044 16.3 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Citrate transporter NEMP PF10225.9 RUS88409.1 - 0.0044 16.7 0.7 0.0068 16.1 0.7 1.3 1 0 0 1 1 1 1 NEMP family MMM1 PF10296.9 RUS88409.1 - 0.0045 16.1 12.2 0.006 15.7 12.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 STT3 PF02516.14 RUS88409.1 - 0.0065 15.5 3.8 0.0083 15.1 3.8 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Nucleoside_tran PF01733.18 RUS88409.1 - 0.0085 15.5 5.3 0.013 14.9 5.3 1.3 1 0 0 1 1 1 1 Nucleoside transporter Ctr PF04145.15 RUS88409.1 - 0.0085 16.7 0.4 0.014 16.0 0.4 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Tetraspanin PF00335.20 RUS88409.1 - 0.0085 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Tetraspanin family Ly49 PF08391.10 RUS88409.1 - 0.0094 16.3 13.7 0.021 15.2 13.7 1.6 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region IgaA PF07095.11 RUS88409.1 - 0.01 13.9 6.1 0.014 13.5 6.1 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Oxysterol_BP PF01237.18 RUS88409.1 - 0.012 14.5 13.8 0.015 14.1 13.8 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Dpy19 PF10034.9 RUS88409.1 - 0.012 13.8 1.7 0.016 13.4 1.7 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation MFS_1 PF07690.16 RUS88409.1 - 0.015 14.2 0.2 0.022 13.7 0.2 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily Halogen_Hydrol PF10112.9 RUS88409.1 - 0.015 15.3 4.7 0.021 14.9 4.7 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Mem_trans PF03547.18 RUS88409.1 - 0.017 13.6 3.7 0.035 12.5 3.7 1.5 1 0 0 1 1 1 0 Membrane transport protein CSG2 PF16965.5 RUS88409.1 - 0.018 14.0 3.1 0.026 13.5 3.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator MFS_2 PF13347.6 RUS88409.1 - 0.018 13.6 0.1 0.028 13.0 0.1 1.4 1 0 0 1 1 1 0 MFS/sugar transport protein Folate_carrier PF01770.18 RUS88409.1 - 0.019 13.7 4.5 0.031 13.0 4.5 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF2561 PF10812.8 RUS88409.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PIG-U PF06728.13 RUS88409.1 - 0.024 13.7 1.2 0.035 13.1 1.2 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U OATP PF03137.20 RUS88409.1 - 0.028 12.7 12.7 0.016 13.5 11.0 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SKN1 PF03935.15 RUS88409.1 - 0.038 12.4 0.5 0.054 11.9 0.5 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) DUF5308 PF17233.2 RUS88409.1 - 0.046 13.9 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Acatn PF13000.7 RUS88409.1 - 0.061 11.8 6.9 0.088 11.3 6.9 1.3 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 EphA2_TM PF14575.6 RUS88409.1 - 0.076 13.9 22.9 1.3 10.0 22.9 2.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FPN1 PF06963.12 RUS88409.1 - 0.083 11.4 2.3 0.11 11.0 2.3 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMEM51 PF15345.6 RUS88409.1 - 0.094 12.5 8.7 0.21 11.4 8.6 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 Ni_hydr_CYTB PF01292.20 RUS88409.1 - 0.099 12.2 1.3 0.19 11.3 1.3 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Herpes_gE PF02480.16 RUS88409.1 - 0.13 11.0 4.6 0.14 10.9 2.5 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E MAPEG PF01124.18 RUS88409.1 - 0.13 12.2 0.4 0.24 11.3 0.3 1.6 1 1 0 1 1 1 0 MAPEG family Miga PF10265.9 RUS88409.1 - 0.15 11.0 9.6 0.2 10.6 9.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4381 PF14316.6 RUS88409.1 - 0.16 12.2 1.4 0.32 11.2 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) BatD PF13584.6 RUS88409.1 - 0.17 10.7 12.1 0.01 14.7 6.6 1.7 1 1 1 2 2 2 0 Oxygen tolerance Pox_Ag35 PF03286.14 RUS88409.1 - 0.21 11.4 26.7 0.31 10.8 26.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sm_multidrug_ex PF06695.11 RUS88409.1 - 0.25 12.0 11.1 0.5 11.0 10.5 1.7 2 0 0 2 2 1 0 Putative small multi-drug export protein Folliculin PF11704.8 RUS88409.1 - 0.26 11.2 8.5 0.4 10.5 8.5 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SLC12 PF03522.15 RUS88409.1 - 0.29 10.1 16.2 0.4 9.7 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3094 PF11293.8 RUS88409.1 - 0.43 10.3 1.4 0.81 9.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) RPN2_C PF18004.1 RUS88409.1 - 0.48 10.3 31.6 0.84 9.5 31.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tmemb_9 PF05434.11 RUS88409.1 - 0.61 10.0 21.8 2.1 8.2 21.8 1.9 1 1 0 1 1 1 0 TMEM9 Conotoxin PF02950.17 RUS88409.1 - 1.1 10.3 10.9 19 6.4 10.9 2.5 1 1 0 1 1 1 0 Conotoxin SCFA_trans PF02667.14 RUS88409.1 - 1.1 8.1 10.5 1.7 7.6 10.5 1.2 1 0 0 1 1 1 0 Short chain fatty acid transporter Rtf2 PF04641.12 RUS88409.1 - 1.6 8.1 30.7 2.6 7.4 30.7 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger TctB PF07331.11 RUS88409.1 - 1.6 9.0 6.3 5.5 7.3 5.9 1.8 1 1 1 2 2 1 0 Tripartite tricarboxylate transporter TctB family TRP PF06011.12 RUS88409.1 - 1.6 7.3 14.0 0.88 8.2 12.2 1.4 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Cytadhesin_P30 PF07271.11 RUS88409.1 - 1.7 8.1 4.4 2.3 7.7 4.4 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 LicD PF04991.13 RUS88409.1 - 2 8.5 20.7 2.8 8.0 20.7 1.2 1 0 0 1 1 1 0 LicD family O-antigen_lig PF13425.6 RUS88409.1 - 2 7.1 31.8 3.7 6.2 31.8 1.4 1 1 0 1 1 1 0 O-antigen ligase like membrane protein GRP PF07172.11 RUS88409.1 - 2.4 8.9 10.3 13 6.6 10.2 2.2 1 1 0 1 1 1 0 Glycine rich protein family Gti1_Pac2 PF09729.9 RUS88409.1 - 2.4 8.2 23.2 3.8 7.6 23.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3807 PF12720.7 RUS88409.1 - 3.3 8.0 27.4 4.8 7.4 27.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TLC PF03219.14 RUS88409.1 - 3.4 6.3 14.4 5.3 5.7 14.4 1.4 1 1 0 1 1 1 0 TLC ATP/ADP transporter IDO PF01231.18 RUS88409.1 - 4.2 6.1 11.5 5.7 5.6 11.5 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF2828 PF11443.8 RUS88409.1 - 4.9 5.1 20.8 6.2 4.8 20.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Scs3p PF10261.9 RUS88409.1 - 7 6.1 8.3 9.1 5.7 7.8 1.4 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Cadherin_C_2 PF16492.5 RUS88409.1 - 8.6 7.2 8.3 14 6.5 6.9 2.1 2 1 0 2 2 1 0 Cadherin cytoplasmic C-terminal Afi1 PF07792.12 RUS88409.1 - 8.8 6.8 16.5 17 5.9 16.5 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4551 PF15087.6 RUS88409.1 - 9.3 4.9 16.7 13 4.5 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) fn3_4 PF16794.5 RUS88410.1 - 3.4e-33 113.6 0.0 7.8e-33 112.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin-III type domain Vps35 PF03635.17 RUS88411.1 - 3.4e-06 25.9 6.8 0.0083 14.7 0.6 2.5 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 35 PRR20 PF15708.5 RUS88411.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 FPL PF09758.9 RUS88412.1 - 5.9e-63 211.3 12.6 1e-62 210.5 12.6 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein TFIIA PF03153.13 RUS88412.1 - 0.065 13.2 33.6 0.038 14.0 25.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 RUS88412.1 - 2.4 9.2 12.4 30 5.6 10.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2362 PF10154.9 RUS88413.1 - 1.3e-193 644.5 3.8 1.5e-193 644.3 3.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF1635 PF07795.11 RUS88413.1 - 1.6 8.6 4.3 0.98 9.2 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) zf-C4 PF00105.18 RUS88416.1 - 1.4e-27 95.9 11.8 2.8e-27 95.0 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS88416.1 - 5.6e-15 55.5 0.1 3.4e-14 52.9 0.1 2.1 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Thioredoxin PF00085.20 RUS88417.1 - 1.3e-63 211.5 0.4 4.1e-33 113.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 RUS88417.1 - 1.2e-45 155.7 10.8 7.1e-40 136.9 2.4 3.6 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 RUS88417.1 - 1.3e-10 41.6 0.5 0.00013 22.4 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 RUS88417.1 - 5.3e-10 39.1 0.0 0.0003 20.2 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RUS88417.1 - 8.4e-08 32.4 0.2 0.036 14.4 0.0 3.4 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 RUS88417.1 - 1.9e-07 31.1 0.1 0.016 15.4 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RUS88417.1 - 3.2e-07 30.3 2.1 0.032 14.2 0.0 3.8 4 0 0 4 4 4 2 AhpC/TSA family ERp29_N PF07912.13 RUS88417.1 - 1.3e-06 28.5 1.8 0.79 9.9 0.0 4.3 4 0 0 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 RUS88417.1 - 0.0012 18.6 1.1 1.3 8.7 0.0 2.9 3 0 0 3 3 3 2 Redoxin HyaE PF07449.11 RUS88417.1 - 0.0058 16.6 0.0 1.2 9.1 0.0 3.2 2 1 1 3 3 3 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 RUS88417.1 - 0.031 14.5 0.1 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin TraF PF13728.6 RUS88417.1 - 0.066 13.0 0.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein MPP6 PF10175.9 RUS88417.1 - 0.07 13.6 0.2 0.15 12.6 0.2 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Linker_histone PF00538.19 RUS88418.1 - 1.5e-29 102.1 1.0 4e-29 100.8 1.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.11 RUS88418.1 - 1.7e-06 28.3 38.3 1.7e-06 28.3 38.3 2.5 1 1 1 2 2 2 1 Histone H1-like nucleoprotein HC2 Pardaxin PF07425.11 RUS88419.1 - 0.04 13.5 0.2 6.7 6.4 0.1 2.5 2 0 0 2 2 2 0 Pardaxin APOBEC1 PF18769.1 RUS88419.1 - 0.29 11.4 1.2 0.6 10.4 0.1 1.9 1 1 1 2 2 2 0 APOBEC1 zf-C2H2_7 PF15269.6 RUS88419.1 - 2.7 8.1 11.8 1.7 8.8 1.0 3.3 2 1 1 3 3 3 0 Zinc-finger Cript PF10235.9 RUS88420.1 - 0.062 13.9 0.3 0.28 11.8 0.3 2.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Nab6_mRNP_bdg PF10567.9 RUS88420.1 - 2.5 7.5 5.6 5.9 6.3 5.6 1.6 1 0 0 1 1 1 0 RNA-recognition motif Nfu_N PF08712.11 RUS88421.1 - 2.4e-30 104.4 0.0 5.9e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 RUS88421.1 - 2.7e-26 91.5 0.1 4.4e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Erp_C PF06780.11 RUS88421.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Erp protein C-terminus UPF0728 PF15092.6 RUS88422.1 - 4.4e-35 119.4 0.0 4.8e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Glyco_hydro_32C PF08244.12 RUS88422.1 - 0.099 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal SE PF08491.10 RUS88423.1 - 4.5 6.2 7.0 7.7 5.5 7.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase PfkB PF00294.24 RUS88425.1 - 8.1e-10 38.5 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 RUS88426.1 - 4.4e-07 29.5 0.0 7.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 RUS88427.1 - 9.8e-49 166.3 0.2 1.2e-48 166.0 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 RUS88427.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MOZ_SAS PF01853.18 RUS88428.1 - 2.4e-76 255.4 0.1 4.5e-76 254.5 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RUS88428.1 - 6.9e-21 73.6 5.0 6.9e-21 73.6 5.0 2.4 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 RUS88428.1 - 5.7e-18 64.6 25.6 3.7e-11 42.7 8.1 3.2 2 1 1 3 3 3 2 PHD-finger Acetyltransf_7 PF13508.7 RUS88428.1 - 0.077 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 RUS88428.1 - 0.079 12.5 11.8 0.043 13.4 1.0 2.9 2 0 0 2 2 2 0 PHD-finger Linker_histone PF00538.19 RUS88428.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.2 4 0 0 4 4 4 0 linker histone H1 and H5 family Prok-RING_1 PF14446.6 RUS88428.1 - 0.23 11.4 15.6 2 8.4 0.6 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C4_ClpX PF06689.13 RUS88428.1 - 1.5 8.7 11.5 2 8.4 4.5 3.3 3 0 0 3 3 3 0 ClpX C4-type zinc finger U3_assoc_6 PF08640.11 RUS88429.1 - 1.8e-26 92.0 8.1 2.2e-24 85.3 7.4 3.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 RUS88429.1 - 1.7e-05 25.3 8.7 28 5.9 0.0 7.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS88429.1 - 0.052 14.1 0.8 26 5.4 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat MAPEG PF01124.18 RUS88429.1 - 0.08 12.8 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 MAPEG family Spt20 PF12090.8 RUS88430.1 - 0.01 15.5 8.0 0.013 15.1 8.0 1.1 1 0 0 1 1 1 0 Spt20 family UPF0524 PF15823.5 RUS88430.1 - 0.015 14.7 0.4 0.021 14.2 0.4 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF4834 PF16118.5 RUS88430.1 - 0.075 14.0 0.8 0.18 12.8 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 RUS88430.1 - 6.2 7.0 15.9 36 4.5 15.9 2.2 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EF-hand_8 PF13833.6 RUS88431.1 - 2.1e-26 91.5 4.9 7.8e-05 22.4 0.2 6.3 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_7 PF13499.6 RUS88431.1 - 1.1e-22 80.3 14.5 7.3e-09 36.0 0.1 6.5 5 1 0 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 RUS88431.1 - 1.7e-19 67.8 5.5 0.00012 21.4 0.0 7.9 7 0 0 7 7 7 5 EF hand EF-hand_11 PF08976.11 RUS88431.1 - 5.5e-17 62.5 2.0 1.4e-05 25.9 0.1 5.2 6 0 0 6 6 6 3 EF-hand domain EF-hand_6 PF13405.6 RUS88431.1 - 6.6e-15 53.7 9.8 0.0001 21.9 0.0 7.8 9 0 0 9 9 9 3 EF-hand domain EF-hand_5 PF13202.6 RUS88431.1 - 3.7e-07 29.3 0.1 0.018 14.6 0.0 5.2 5 0 0 5 5 5 1 EF hand DUF5580 PF17743.1 RUS88431.1 - 0.0063 15.1 0.0 2.1 6.8 0.0 2.8 2 1 0 2 2 2 2 Family of unknown function (DUF5580) S-AdoMet_synt_C PF02773.16 RUS88432.1 - 3.2e-68 228.0 0.4 7.8e-68 226.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 RUS88432.1 - 7.3e-46 155.3 0.0 1.8e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 RUS88432.1 - 2.1e-44 150.2 1.5 2.9e-44 149.8 0.3 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 RUS88432.1 - 0.014 14.2 1.1 0.088 11.6 0.2 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) VKG_Carbox PF05090.14 RUS88434.1 - 2.5e-147 491.2 13.8 3.1e-147 490.9 13.8 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Cupin_2 PF07883.11 RUS88434.1 - 0.00089 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Retrotrans_gag PF03732.17 RUS88434.1 - 0.017 15.4 0.7 0.059 13.7 0.7 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Vps53_N PF04100.12 RUS88434.1 - 0.028 13.4 0.0 0.048 12.6 0.0 1.4 1 1 0 1 1 1 0 Vps53-like, N-terminal DoxX PF07681.12 RUS88434.1 - 0.044 14.4 0.6 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 DoxX PhzC-PhzF PF02567.16 RUS88435.1 - 1.8e-54 185.1 0.1 6.7e-54 183.3 0.1 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Methyltransf_11 PF08241.12 RUS88436.1 - 0.00038 21.0 0.0 0.0011 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS88436.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 RUS88436.1 - 0.011 14.3 0.0 0.012 14.2 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 RUS88436.1 - 0.022 14.6 0.0 0.069 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RUS88436.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RUS88437.1 - 1.4e-11 44.8 0.0 2.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS88437.1 - 4.9e-11 43.2 0.0 7.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS88437.1 - 3.2e-09 36.8 0.0 4.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS88437.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS88437.1 - 9.1e-06 26.4 0.0 1.7e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RUS88437.1 - 0.025 14.2 0.0 0.066 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_29 PF03141.16 RUS88437.1 - 0.03 12.9 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AKNA PF12443.8 RUS88437.1 - 0.062 14.0 0.0 0.094 13.4 0.0 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor Pelovaterin PF17859.1 RUS88438.1 - 1.3 9.4 8.2 13 6.2 1.1 2.7 2 0 0 2 2 2 0 Pelovaterin DUF1189 PF06691.11 RUS88438.1 - 7.8 6.0 20.3 5.4 6.5 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) 7TM_GPCR_Srw PF10324.9 RUS88439.1 - 8.9e-10 38.4 5.9 1.1e-09 38.0 5.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS88439.1 - 0.023 14.0 6.7 0.03 13.7 6.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 RUS88439.1 - 1.6 7.4 5.6 1.2 7.8 2.7 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Rab5ip PF07019.12 RUS88439.1 - 3.2 8.4 7.4 3 8.5 0.9 2.7 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) 7TM_GPCR_Srx PF10328.9 RUS88440.1 - 1e-07 31.9 17.7 1e-07 31.9 17.7 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS88440.1 - 2.6e-06 27.0 24.8 0.00014 21.3 24.8 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS88440.1 - 9.4e-06 25.1 16.1 1.5e-05 24.4 16.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS88440.1 - 0.0019 17.6 21.4 0.019 14.4 21.4 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Homeodomain PF00046.29 RUS88444.1 - 5.2e-22 77.4 6.5 8.6e-22 76.7 6.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS88444.1 - 0.019 14.9 0.4 0.049 13.5 0.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 RUS88444.1 - 0.032 14.6 0.1 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 RUS88447.1 - 1.6e-20 72.7 8.8 3e-20 71.8 8.8 1.5 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 RUS88447.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) SDA1 PF05285.12 RUS88448.1 - 0.0033 16.9 31.8 0.0037 16.7 31.8 1.1 1 0 0 1 1 1 1 SDA1 MAM33 PF02330.16 RUS88448.1 - 5.7 6.8 11.5 0.38 10.7 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein Homeodomain PF00046.29 RUS88449.1 - 4.7e-22 77.6 9.5 9.4e-22 76.6 9.5 1.5 1 0 0 1 1 1 1 Homeodomain Terminase_5 PF06056.12 RUS88449.1 - 0.038 13.9 1.2 0.1 12.5 0.2 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Hat1_N PF10394.9 RUS88450.1 - 8.8e-48 162.6 1.3 2.3e-47 161.2 0.5 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 RUS88450.1 - 0.0028 17.4 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Translin PF01997.16 RUS88451.1 - 4.5e-57 193.4 0.5 5.2e-57 193.1 0.5 1.0 1 0 0 1 1 1 1 Translin family SesA PF17107.5 RUS88451.1 - 0.0061 16.7 0.3 0.01 16.1 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TMEM156 PF15106.6 RUS88451.1 - 0.0064 16.0 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 TMEM156 protein family Med30 PF11315.8 RUS88451.1 - 0.016 15.4 0.4 0.054 13.7 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 30 IL11 PF07400.11 RUS88451.1 - 0.022 14.4 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 Interleukin 11 OSTMP1 PF09777.9 RUS88451.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Phage_TAC_9 PF10876.8 RUS88451.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Phage tail assemb.y chaperone protein, TAC Complex1_LYR_2 PF13233.6 RUS88452.1 - 8.4e-17 61.7 1.6 1e-16 61.4 1.6 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RUS88452.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Costars PF14705.6 RUS88455.1 - 4.6e-28 97.2 0.1 5e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 Costars GED PF02212.18 RUS88456.1 - 0.00011 22.3 16.3 25 5.1 0.1 6.8 1 1 6 7 7 7 6 Dynamin GTPase effector domain Peptidase_S46 PF10459.9 RUS88456.1 - 0.00019 20.3 5.7 0.067 11.8 1.4 2.4 1 1 0 2 2 2 2 Peptidase S46 Dynein_IC2 PF11540.8 RUS88456.1 - 0.17 11.8 11.9 3.4e+02 1.3 0.0 7.4 8 0 0 8 8 8 0 Cytoplasmic dynein 1 intermediate chain 2 FAST_1 PF06743.15 RUS88457.1 - 2.3e-09 37.1 2.7 6.2e-09 35.7 0.1 3.0 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 DnaJ-X PF14308.6 RUS88457.1 - 0.19 11.1 0.1 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing IQ PF00612.27 RUS88458.1 - 0.0059 16.3 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif CAP_GLY PF01302.25 RUS88461.1 - 7.6e-18 64.3 0.2 1.3e-17 63.6 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF4378 PF14309.6 RUS88461.1 - 1e-06 29.2 0.7 6.8e-05 23.3 0.1 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4378) CENP-F_leu_zip PF10473.9 RUS88461.1 - 0.046 13.7 6.6 0.19 11.8 6.6 2.0 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF916 PF06030.12 RUS88462.1 - 0.069 13.2 1.8 12 6.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Laminin_EGF PF00053.24 RUS88463.1 - 3.5e-51 171.1 135.0 9.7e-10 38.4 15.7 7.3 7 0 0 7 7 7 7 Laminin EGF domain ATG16 PF08614.11 RUS88463.1 - 0.00014 22.2 3.1 0.00014 22.2 3.1 5.1 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) DUF4111 PF13427.6 RUS88463.1 - 0.0014 18.7 0.9 0.14 12.3 0.3 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4111) T3SS_needle_E PF08988.10 RUS88463.1 - 0.039 14.1 0.1 0.039 14.1 0.1 3.8 4 0 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle Laminin_II PF06009.12 RUS88463.1 - 0.4 10.7 59.9 0.048 13.7 4.7 6.4 3 1 3 7 7 7 0 Laminin Domain II YadA_stalk PF05662.14 RUS88463.1 - 0.77 10.2 5.2 7.7 7.0 0.3 3.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin ASL_C2 PF14698.6 RUS88463.1 - 4.3 8.2 7.3 50 4.7 0.1 4.2 3 0 0 3 3 3 0 Argininosuccinate lyase C-terminal Mpv17_PMP22 PF04117.12 RUS88464.1 - 0.03 14.6 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF2052 PF09747.9 RUS88464.1 - 0.85 9.7 29.0 1.3 9.1 29.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 RUS88464.1 - 1.8 8.3 42.8 2.4 7.9 42.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 RUS88464.1 - 1.9 6.8 7.8 2.3 6.5 7.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_11 PF13086.6 RUS88464.1 - 3.3 7.4 27.6 6.4 6.5 27.6 1.6 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.21 RUS88465.1 - 8.1e-14 51.6 16.8 1.2e-11 44.4 12.9 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Mpp10 PF04006.12 RUS88465.1 - 0.0047 15.4 13.7 0.0061 15.1 13.7 1.1 1 0 0 1 1 1 1 Mpp10 protein SAPS PF04499.15 RUS88465.1 - 0.047 12.5 0.2 0.056 12.2 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein 7TM_GPCR_Sru PF10322.9 RUS88465.1 - 0.071 12.4 9.7 0.072 12.4 8.0 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru 7TM_GPCR_Srx PF10328.9 RUS88465.1 - 0.11 12.0 13.1 0.027 14.1 6.6 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Nop14 PF04147.12 RUS88465.1 - 2 6.5 32.8 2.8 6.1 32.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS88465.1 - 4.7 5.4 27.2 7 4.8 27.2 1.1 1 0 0 1 1 1 0 CDC45-like protein EGF_2 PF07974.13 RUS88466.1 - 2.4 8.6 6.8 6.7 7.2 6.9 1.8 1 1 0 1 1 1 0 EGF-like domain Abhydrolase_4 PF08386.10 RUS88467.1 - 3.7e-05 23.8 0.7 61 3.8 0.0 6.1 2 2 5 7 7 7 3 TAP-like protein GAGA_bind PF06217.12 RUS88467.1 - 0.087 13.1 0.7 0.13 12.5 0.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SufE PF02657.15 RUS88468.1 - 0.13 12.1 0.7 13 5.7 0.1 3.6 1 1 5 6 6 6 0 Fe-S metabolism associated domain DUF2577 PF10844.8 RUS88468.1 - 0.66 10.2 4.6 30 4.9 4.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) CSRNP_N PF16019.5 RUS88468.1 - 3.1 7.7 4.7 16 5.3 0.1 3.3 1 1 2 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus DUF2664 PF10867.8 RUS88468.1 - 4 7.9 5.6 24 5.4 0.3 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF2664) Myosin_head PF00063.21 RUS88469.1 - 8e-202 672.1 0.5 4.2e-201 669.7 0.5 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 RUS88469.1 - 1.1e-32 113.5 0.0 3e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88469.1 - 1.5e-22 80.1 0.0 3.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 RUS88469.1 - 2.6e-18 64.0 41.3 0.00068 19.2 2.4 6.6 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.6 RUS88469.1 - 0.00013 22.2 0.0 0.00045 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS88469.1 - 0.036 14.4 0.4 0.3 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain APH PF01636.23 RUS88469.1 - 0.26 11.2 0.9 0.58 10.0 0.9 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 RUS88470.1 - 1.4e-18 66.2 8.8 0.0077 16.2 0.0 8.2 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS88470.1 - 4.6e-06 26.9 0.4 0.14 12.5 0.0 6.0 3 3 3 6 6 6 2 HEAT repeats DUF3361 PF11841.8 RUS88470.1 - 0.00016 21.7 7.6 0.96 9.4 0.9 5.2 3 2 3 6 6 6 4 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 RUS88470.1 - 0.034 14.2 11.8 3.6 7.7 0.1 6.1 5 2 2 7 7 7 0 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 RUS88470.1 - 0.044 14.0 3.2 3.8 7.7 0.2 4.7 4 2 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 RUS88470.1 - 0.083 13.0 2.4 0.75 9.9 0.1 3.4 3 1 1 4 4 4 0 V-ATPase subunit H V-ATPase_H_N PF03224.14 RUS88470.1 - 0.11 11.8 13.5 0.06 12.6 2.1 3.7 2 2 0 3 3 3 0 V-ATPase subunit H HEAT PF02985.22 RUS88470.1 - 0.25 11.7 13.0 16 6.1 0.0 7.7 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 RUS88470.1 - 0.28 11.8 14.1 7.4 7.2 0.0 7.6 7 3 2 9 9 9 0 HEAT-like repeat DUF2990 PF11693.8 RUS88471.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) DFRP_C PF16543.5 RUS88472.1 - 6.4e-22 77.9 4.2 6.4e-22 77.9 4.2 3.6 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 RUS88472.1 - 5e-07 29.4 5.1 7.2e-06 25.7 1.1 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 RUS88472.1 - 6.5e-07 29.1 1.1 6.5e-07 29.1 1.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS88472.1 - 2.2e-06 27.5 17.0 3e-06 27.1 6.4 2.8 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 RUS88472.1 - 6.3e-06 26.9 19.4 1.7e-05 25.4 3.6 3.9 1 1 2 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 RUS88472.1 - 6.3e-05 23.3 9.2 0.034 14.6 2.1 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RUS88472.1 - 0.00074 19.7 0.9 0.08 13.2 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger containing family HV_small_capsid PF17086.5 RUS88472.1 - 4.8 7.5 6.7 1.6 9.1 0.2 2.8 2 0 0 2 2 2 0 Small capsid protein of Herpesviridae Rhomboid PF01694.22 RUS88473.1 - 9.1e-27 93.9 6.0 9.1e-27 93.9 6.0 2.1 3 0 0 3 3 3 1 Rhomboid family DUF389 PF04087.14 RUS88473.1 - 0.012 15.6 0.5 0.035 14.1 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF389) MADF_DNA_bdg PF10545.9 RUS88474.1 - 6.3e-18 64.9 1.4 1.1e-17 64.2 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 RUS88474.1 - 0.0073 16.7 2.5 0.012 16.0 2.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PP1_bind PF15276.6 RUS88474.1 - 0.26 11.6 6.8 0.35 11.2 2.4 2.4 2 0 0 2 2 2 0 Protein phosphatase 1 binding HTH_51 PF18558.1 RUS88475.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ham1p_like PF01725.16 RUS88476.1 - 3.6e-41 141.1 0.0 4.1e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family dCache_1 PF02743.18 RUS88477.1 - 4.1e-12 46.4 0.7 4.3e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Cache domain VGCC_alpha2 PF08473.11 RUS88477.1 - 7e-06 25.1 0.6 0.014 14.2 0.2 3.1 3 0 0 3 3 3 3 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 RUS88477.1 - 0.074 13.5 0.0 0.33 11.5 0.0 2.0 1 1 0 1 1 1 0 VWA N-terminal TP6A_N PF04406.14 RUS88480.1 - 9.2e-22 76.8 0.2 1.6e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase PDZ PF00595.24 RUS88481.1 - 1e-07 32.2 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF1647 PF07801.11 RUS88482.1 - 7.5e-06 25.7 0.2 1.5e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) MutS_V PF00488.21 RUS88483.1 - 6.6e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_V PF00488.21 RUS88484.1 - 5e-40 137.5 0.0 8.7e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RUS88484.1 - 2.2e-27 96.5 0.0 4.3e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain III Gemini_AC4_5 PF04807.12 RUS88484.1 - 0.0012 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Geminivirus AC4/5 conserved region MutS_IV PF05190.18 RUS88484.1 - 0.0036 17.6 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV Rad17 PF03215.15 RUS88484.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Jun PF03957.13 RUS88485.1 - 4.9e-39 134.6 9.0 7.7e-39 133.9 9.0 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 RUS88485.1 - 4.3e-17 62.0 9.6 4.3e-17 62.0 9.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RUS88485.1 - 1.4e-07 31.5 11.5 4e-07 30.0 11.5 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS88485.1 - 1.1e-06 29.1 5.9 2.9e-06 27.7 5.9 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor MADF_DNA_bdg PF10545.9 RUS88486.1 - 5.2e-16 58.7 3.0 5.2e-16 58.7 3.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 RUS88486.1 - 0.02 15.2 1.8 0.02 15.2 1.8 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain LRR_4 PF12799.7 RUS88487.1 - 5e-06 26.8 6.0 0.00069 19.9 1.4 5.1 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS88487.1 - 6.6e-06 25.8 3.2 0.26 11.4 0.2 4.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 RUS88487.1 - 0.0015 18.2 2.0 0.0015 18.2 2.0 3.5 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 RUS88487.1 - 0.1 13.2 10.9 1.8 9.4 0.1 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat Homeodomain PF00046.29 RUS88490.1 - 5.6e-20 70.9 4.2 8.8e-20 70.3 4.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS88490.1 - 0.023 14.6 0.2 0.053 13.4 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4207 PF13904.6 RUS88490.1 - 0.048 13.4 10.0 0.07 12.8 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Tmemb_cc2 PF10267.9 RUS88490.1 - 1.8 7.6 10.1 2.5 7.1 10.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 RUS88490.1 - 1.8 7.0 13.9 2.1 6.8 13.9 1.2 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 RUS88490.1 - 4.1 7.4 16.9 7.1 6.6 16.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PKD PF00801.20 RUS88491.1 - 0.014 15.2 7.3 0.12 12.2 0.7 3.5 3 2 0 3 3 3 0 PKD domain PKD PF00801.20 RUS88492.1 - 8.1e-11 41.6 5.2 1.8e-10 40.5 1.4 2.7 3 0 0 3 3 3 1 PKD domain Wzt_C PF14524.6 RUS88492.1 - 0.015 15.4 0.1 0.14 12.2 0.0 2.0 1 1 1 2 2 2 0 Wzt C-terminal domain Y_Y_Y PF07495.13 RUS88492.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain Big_7 PF17957.1 RUS88492.1 - 5.6 7.8 9.3 8.1 7.3 5.7 2.7 1 1 1 2 2 2 0 Bacterial Ig domain PKD PF00801.20 RUS88493.1 - 1.7e-08 34.2 0.8 9.7e-07 28.5 0.2 2.5 2 0 0 2 2 2 2 PKD domain CAF1C_H4-bd PF12265.8 RUS88493.1 - 0.018 15.3 0.2 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex WSC PF01822.19 RUS88494.1 - 2.9e-14 53.0 5.7 4.7e-14 52.3 5.7 1.3 1 0 0 1 1 1 1 WSC domain PKD PF00801.20 RUS88494.1 - 4.5e-05 23.2 0.6 9.6e-05 22.2 0.6 1.5 1 0 0 1 1 1 1 PKD domain Y_Y_Y PF07495.13 RUS88494.1 - 0.02 14.8 0.4 0.04 13.9 0.1 1.7 2 0 0 2 2 2 0 Y_Y_Y domain SRX PF09201.10 RUS88496.1 - 0.00016 21.5 6.2 10 5.9 0.0 5.4 1 1 5 6 6 6 3 SRX, signal recognition particle receptor alpha subunit KfrB PF18790.1 RUS88496.1 - 0.026 14.7 0.2 1.6e+02 2.6 0.0 5.6 4 2 2 7 7 7 0 KfrB protein CFTR_R PF14396.6 RUS88496.1 - 0.11 12.0 28.3 10 5.6 6.7 7.3 1 1 4 5 5 5 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Ribosomal_L27_C PF18471.1 RUS88496.1 - 0.24 10.8 3.5 11 5.3 0.1 3.8 1 1 7 8 8 8 0 Ribosomal L27 protein C-terminal domain DUF5447 PF17525.2 RUS88496.1 - 5.9 7.4 22.9 4.8 7.7 0.8 5.6 1 1 3 4 4 4 0 Family of unknown function (DUF5447) VSG_B PF13206.6 RUS88497.1 - 0.12 11.7 0.2 0.16 11.2 0.2 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Requiem_N PF14051.6 RUS88498.1 - 1.5e-29 102.0 0.8 3.5e-29 100.8 0.8 1.7 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 RUS88498.1 - 3.6e-21 74.8 21.7 5e-13 48.7 4.8 2.7 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 RUS88498.1 - 0.00061 19.8 7.2 0.00061 19.8 7.2 2.9 1 1 1 2 2 2 1 PHD-finger Lar_restr_allev PF14354.6 RUS88498.1 - 0.012 16.0 1.4 0.012 16.0 1.4 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar PHD_2 PF13831.6 RUS88498.1 - 0.021 14.4 1.2 0.021 14.4 1.2 3.3 2 1 1 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 RUS88498.1 - 0.11 12.2 14.7 0.21 11.2 1.9 3.2 1 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain UPF0547 PF10571.9 RUS88498.1 - 0.15 12.2 3.2 13 6.0 0.9 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 RUS88498.1 - 0.23 11.7 6.3 6.5 7.0 0.3 3.1 2 1 0 3 3 3 0 C4-type zinc ribbon domain Prok-RING_1 PF14446.6 RUS88498.1 - 0.47 10.4 19.5 0.29 11.1 0.8 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 RUS88498.1 - 0.59 10.1 19.8 0.28 11.1 0.8 3.6 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RanBP PF00641.18 RUS88498.1 - 4 6.8 8.8 7 6.1 0.6 3.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ceramidase_alk PF04734.13 RUS88499.1 - 3.5e-228 758.3 0.5 4.1e-228 758.1 0.5 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 RUS88499.1 - 6.7e-57 192.0 0.3 1.1e-56 191.3 0.3 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal TEX33 PF15400.6 RUS88500.1 - 3.3e-18 66.5 0.5 7e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Testis-expressed sequence 33 protein family FAM75 PF14650.6 RUS88500.1 - 0.001 18.7 3.6 0.0043 16.7 3.6 2.0 1 0 0 1 1 1 1 FAM75 family TEX33 PF15400.6 RUS88501.1 - 4.1e-05 24.1 1.2 5.4e-05 23.7 0.7 1.4 1 1 0 1 1 1 1 Testis-expressed sequence 33 protein family Thioredoxin PF00085.20 RUS88502.1 - 1e-27 96.1 0.0 1.4e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RUS88502.1 - 2.2e-09 37.7 0.0 6.1e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RUS88502.1 - 1.5e-07 31.3 0.0 4.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.6 RUS88502.1 - 3.1e-06 27.3 0.0 6.6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 RUS88502.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 RUS88502.1 - 8.3e-05 22.9 0.0 0.00049 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 RUS88502.1 - 0.00016 22.0 0.0 0.042 14.2 0.0 3.0 1 1 2 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 RUS88502.1 - 0.0013 18.6 0.0 0.0085 16.0 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 RUS88502.1 - 0.0028 17.9 0.1 0.08 13.2 0.0 2.4 2 1 0 2 2 2 1 Glutaredoxin OST3_OST6 PF04756.13 RUS88502.1 - 0.0098 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 RUS88502.1 - 0.015 15.0 0.2 0.44 10.3 0.0 2.2 1 1 1 2 2 2 0 Redoxin DSBA PF01323.20 RUS88502.1 - 0.019 14.8 0.0 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_6 PF13848.6 RUS88502.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2847 PF11009.8 RUS88502.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin_4 PF13462.6 RUS88502.1 - 0.095 12.8 0.0 14 5.8 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Nop25 PF09805.9 RUS88503.1 - 1.8e-10 41.4 14.6 1.8e-10 41.4 14.6 2.3 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) Filo_glycop PF01611.16 RUS88504.1 - 0.16 10.9 0.7 0.82 8.5 0.3 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein DUF1425 PF07233.12 RUS88504.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Ank_2 PF12796.7 RUS88505.1 - 7.7e-10 39.2 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 RUS88505.1 - 1.5e-08 34.7 0.2 1.6e-06 28.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 RUS88505.1 - 6.7e-08 32.7 0.1 2.4e-07 30.9 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88505.1 - 8.2e-08 31.9 0.0 1.1e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS88505.1 - 1.7e-05 25.3 0.1 3.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Oxidored_FMN PF00724.20 RUS88505.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family E3_UbLigase_R4 PF13764.6 RUS88506.1 - 0 1086.4 2.8 0 1085.2 2.8 1.6 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DZR PF12773.7 RUS88506.1 - 0.32 11.1 20.2 0.091 12.8 12.9 3.1 2 0 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.9 RUS88506.1 - 1.5 9.0 7.2 5 7.3 7.2 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Sporozoite_P67 PF05642.11 RUS88506.1 - 1.6 6.7 23.1 3.1 5.8 23.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF913 PF06025.12 RUS88506.1 - 1.8 7.4 5.4 0.95 8.4 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) RRM_1 PF00076.22 RUS88508.1 - 3.6e-13 49.1 0.1 6e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 RUS88508.1 - 4.5e-06 27.3 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 RUS88508.1 - 2e-05 24.5 2.7 2e-05 24.5 2.7 2.0 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 RUS88508.1 - 2.8e-05 24.0 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 RUS88508.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_3 PF15663.5 RUS88508.1 - 0.0085 16.3 0.8 0.033 14.4 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger containing family RRM_3 PF08777.11 RUS88508.1 - 0.016 15.3 0.1 0.042 13.9 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif FYVE PF01363.21 RUS88508.1 - 0.018 15.1 1.3 0.018 15.1 1.3 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_4 PF18044.1 RUS88508.1 - 0.021 14.6 2.0 0.052 13.4 2.0 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 RUS88508.1 - 0.029 14.3 2.1 0.029 14.3 2.1 2.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 RUS88508.1 - 0.53 10.8 4.1 0.15 12.5 0.6 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 RUS88508.1 - 0.99 9.4 8.6 2.3 8.3 8.6 1.6 1 0 0 1 1 1 0 zinc-ribbons 7tm_1 PF00001.21 RUS88509.1 - 2.2e-46 158.3 22.2 2.7e-46 158.0 22.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS88509.1 - 4.5e-05 22.9 23.0 0.00021 20.8 23.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Homeodomain PF00046.29 RUS88510.1 - 2.6e-12 46.4 0.1 5.8e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS88510.1 - 0.025 14.5 3.1 0.061 13.2 0.1 3.2 3 1 0 3 3 3 0 Homeobox KN domain 7tm_2 PF00002.24 RUS88511.1 - 1.5e-10 40.8 13.1 2e-10 40.4 13.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Mob1_phocein PF03637.17 RUS88512.1 - 5.5e-84 280.3 0.1 6.8e-84 280.0 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family FH2 PF02181.23 RUS88513.1 - 7.7e-67 226.0 11.8 9.6e-52 176.3 2.8 3.0 2 1 1 3 3 3 3 Formin Homology 2 Domain DNA_pack_N PF02500.15 RUS88513.1 - 0.081 12.7 1.5 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus TBCC_N PF16752.5 RUS88513.1 - 0.4 11.1 6.0 0.77 10.2 0.5 2.9 3 1 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Phe_tRNA-synt_N PF02912.18 RUS88514.1 - 0.0075 16.2 0.0 19 5.3 0.0 3.9 2 1 1 3 3 3 2 Aminoacyl tRNA synthetase class II, N-terminal domain UN_NPL4 PF11543.8 RUS88514.1 - 0.023 15.2 11.0 9 6.9 0.0 5.7 1 1 4 5 5 5 0 Nuclear pore localisation protein NPL4 ARL2_Bind_BART PF11527.8 RUS88516.1 - 0.13 12.4 5.1 2.1 8.5 0.0 3.6 4 0 0 4 4 4 0 The ARF-like 2 binding protein BART EF1_GNE PF00736.19 RUS88517.1 - 1.8e-33 114.6 0.3 3.5e-33 113.6 0.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RUS88517.1 - 2.4e-09 37.4 5.3 2.4e-09 37.4 5.3 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.4 RUS88517.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MinC_N PF05209.13 RUS88517.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Ank_2 PF12796.7 RUS88519.1 - 3.6e-57 190.9 18.5 9.8e-17 61.3 2.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS88519.1 - 3.1e-38 129.7 3.5 7e-11 42.4 0.2 4.9 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88519.1 - 3.4e-35 116.1 4.1 3.1e-05 24.0 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 RUS88519.1 - 4.3e-33 112.9 11.6 3.4e-10 40.0 0.1 6.8 2 2 6 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS88519.1 - 2e-32 110.2 9.1 1.3e-06 28.5 0.0 7.9 8 1 1 9 9 9 6 Ankyrin repeat Death PF00531.22 RUS88519.1 - 6.2e-08 32.7 0.4 1.5e-07 31.5 0.4 1.7 1 0 0 1 1 1 1 Death domain Phage_tail_L PF05100.12 RUS88522.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein L Asn_synthase PF00733.21 RUS88523.1 - 2.9e-80 270.6 0.4 1.3e-50 173.1 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 RUS88523.1 - 5.4e-25 87.7 0.0 1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RUS88523.1 - 4.1e-19 69.1 0.0 8.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 RUS88523.1 - 5.4e-07 29.0 0.1 8.7e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 RUS88523.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 RUS88523.1 - 0.0029 16.5 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 RUS88523.1 - 0.0043 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 RUS88523.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Kelch_1 PF01344.25 RUS88524.1 - 1.2e-40 136.9 5.1 1.6e-10 40.4 0.0 5.4 5 0 0 5 5 5 5 Kelch motif BTB PF00651.31 RUS88524.1 - 1.9e-26 92.5 0.5 1.7e-25 89.4 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS88524.1 - 6.4e-25 87.2 0.5 1.4e-24 86.1 0.5 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS88524.1 - 5.1e-22 77.4 0.7 3.5e-06 27.1 0.0 5.7 2 1 3 5 5 5 5 Kelch motif Kelch_3 PF13415.6 RUS88524.1 - 7.3e-13 48.5 1.3 0.0024 18.1 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS88524.1 - 1e-12 47.7 5.5 0.069 13.2 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS88524.1 - 5.4e-10 38.9 0.5 0.25 11.4 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 RUS88524.1 - 2.3e-09 37.1 0.0 0.16 12.0 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Hydrophob_seed PF14547.6 RUS88524.1 - 0.059 13.6 3.0 0.071 13.3 0.8 2.3 2 0 0 2 2 2 0 Hydrophobic seed protein Ashwin PF15323.6 RUS88524.1 - 0.11 12.4 2.8 0.19 11.7 2.8 1.3 1 0 0 1 1 1 0 Developmental protein Piezo_RRas_bdg PF12166.8 RUS88527.1 - 3.5e-124 415.3 1.6 5.8e-124 414.6 1.6 1.4 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 RUS88527.1 - 1e-42 146.2 5.1 4.1e-39 134.4 3.5 2.4 1 1 1 2 2 2 2 Piezo Piezo_RRas_bdg PF12166.8 RUS88528.1 - 5.5e-22 78.6 3.6 6.4e-22 78.4 3.6 1.1 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Ion_trans_2 PF07885.16 RUS88529.1 - 4.6e-16 58.6 14.3 6e-11 42.2 9.1 2.5 2 0 0 2 2 2 2 Ion channel Mucin PF01456.17 RUS88529.1 - 9.8 6.2 12.4 5 7.1 10.0 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Motile_Sperm PF00635.26 RUS88530.1 - 9.9e-34 115.5 0.1 1.5e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain cNMP_binding PF00027.29 RUS88531.1 - 0.00081 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HSNSD PF12062.8 RUS88532.1 - 1.9e-166 554.7 0.1 2.7e-166 554.1 0.1 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 RUS88532.1 - 5.6e-35 121.1 0.2 9.4e-35 120.4 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS88532.1 - 2.9e-10 40.9 0.4 0.00054 20.4 0.2 2.7 1 1 1 2 2 2 2 Sulfotransferase family TCP PF03634.13 RUS88533.1 - 0.00025 21.7 21.3 0.00095 19.8 13.8 2.2 2 0 0 2 2 2 1 TCP family transcription factor CDC45 PF02724.14 RUS88533.1 - 0.0018 16.6 26.4 0.0018 16.6 26.4 2.0 2 0 0 2 2 2 1 CDC45-like protein BORG_CEP PF14957.6 RUS88533.1 - 0.0059 17.8 6.7 0.0059 17.8 6.7 2.2 2 0 0 2 2 2 1 Cdc42 effector eIF3_subunit PF08597.10 RUS88533.1 - 0.0086 16.0 42.0 0.0086 16.0 42.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit RPOL_N PF14700.6 RUS88533.1 - 0.011 15.2 23.9 0.011 15.2 23.9 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF5308 PF17233.2 RUS88533.1 - 0.019 15.2 8.6 0.024 14.8 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Tim54 PF11711.8 RUS88533.1 - 0.081 11.7 25.1 0.012 14.5 18.7 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Endostatin PF06482.11 RUS88533.1 - 0.11 11.9 14.3 0.07 12.6 7.0 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin LTV PF04180.14 RUS88533.1 - 0.13 12.0 26.5 0.015 15.1 19.1 2.0 2 0 0 2 2 2 0 Low temperature viability protein RNA_pol_Rpc4 PF05132.14 RUS88533.1 - 0.32 11.4 29.1 0.05 14.0 23.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ctr PF04145.15 RUS88533.1 - 0.44 11.2 10.2 0.13 12.8 3.5 2.2 2 0 0 2 2 2 0 Ctr copper transporter family RR_TM4-6 PF06459.12 RUS88533.1 - 0.68 9.7 39.0 0.093 12.5 31.6 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FancD2 PF14631.6 RUS88533.1 - 0.83 7.0 21.1 1.1 6.5 21.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SLC12 PF03522.15 RUS88533.1 - 0.92 8.5 31.9 0.04 13.0 20.6 2.0 2 0 0 2 2 2 0 Solute carrier family 12 PA26 PF04636.13 RUS88533.1 - 0.94 8.3 15.7 0.05 12.5 8.1 1.9 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) AAA_11 PF13086.6 RUS88533.1 - 1.4 8.6 36.0 2.8 7.7 36.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2052 PF09747.9 RUS88533.1 - 1.5 8.9 24.6 0.42 10.7 17.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Zip PF02535.22 RUS88533.1 - 3.3 6.8 24.4 0.13 11.5 17.1 1.8 1 1 1 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 RUS88533.1 - 3.4 6.3 28.2 0.2 10.4 16.9 2.1 2 0 0 2 2 2 0 Presenilin CSRNP_N PF16019.5 RUS88533.1 - 3.4 7.5 21.6 2 8.3 13.7 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus NPR3 PF03666.13 RUS88533.1 - 6.3 5.5 37.6 0.23 10.2 28.2 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 IHABP4_N PF16174.5 RUS88533.1 - 6.7 7.3 51.8 2 9.0 2.5 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Vfa1 PF08432.10 RUS88533.1 - 8.1 6.7 58.2 2.1 8.6 47.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4175 PF13779.6 RUS88533.1 - 9.5 4.0 28.9 0.34 8.8 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PTPlike_phytase PF14566.6 RUS88534.1 - 1.2e-40 139.2 0.1 6.2e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RUS88534.1 - 0.0022 18.0 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family SapB_1 PF05184.15 RUS88535.1 - 1.9e-189 612.6 117.8 6.3e-15 54.8 1.2 17.4 16 0 0 16 16 16 14 Saposin-like type B, region 1 SapB_2 PF03489.17 RUS88535.1 - 2.5e-150 488.1 134.3 2e-11 43.8 2.2 16.6 16 0 0 16 16 16 14 Saposin-like type B, region 2 RFC1 PF08519.12 RUS88535.1 - 3.4e-16 59.8 5.2 6.8 6.8 0.0 11.9 7 4 3 12 12 12 1 Replication factor RFC1 C terminal domain HD_3 PF13023.6 RUS88535.1 - 1.8e-14 54.0 11.2 32 4.4 0.0 12.7 13 0 0 13 13 13 0 HD domain Disaggr_repeat PF06848.11 RUS88535.1 - 2.5e-11 43.6 0.0 59 3.3 0.0 10.4 12 0 0 12 12 12 0 Disaggregatase related repeat DUF445 PF04286.12 RUS88535.1 - 1.4e-08 34.9 11.3 0.39 10.5 0.0 8.6 3 1 3 6 6 6 1 Protein of unknown function (DUF445) SapA PF02199.15 RUS88535.1 - 3e-07 30.6 8.2 3e-07 30.6 8.2 2.9 2 0 0 2 2 2 1 Saposin A-type domain DUF4359 PF14271.6 RUS88535.1 - 9.1e-07 29.6 73.6 4.7 8.0 0.2 14.4 15 0 0 15 15 13 2 Domain of unknown function (DUF4359) AbiEi_1 PF09407.10 RUS88535.1 - 5e-06 26.9 0.0 3.3e+02 1.5 0.0 9.2 10 0 0 10 10 10 0 AbiEi antitoxin C-terminal domain Nramp PF01566.18 RUS88535.1 - 0.00014 21.0 0.3 6.4 5.6 0.0 5.4 6 0 0 6 6 6 1 Natural resistance-associated macrophage protein DNA_ligase_C PF17879.1 RUS88535.1 - 0.0012 18.8 0.2 1.7e+02 2.3 0.0 7.0 9 0 0 9 9 9 0 DNA ligase C-terminal domain NADH_4Fe-4S PF10589.9 RUS88535.1 - 0.049 13.7 53.9 15 5.8 0.3 12.3 12 0 0 12 12 12 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HEAT_EZ PF13513.6 RUS88535.1 - 0.071 13.6 38.1 1.5e+02 3.0 0.1 12.9 14 0 0 14 14 14 0 HEAT-like repeat DUF935 PF06074.12 RUS88535.1 - 0.13 10.9 0.4 23 3.5 0.0 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF935) NTS_2 PF15448.6 RUS88535.1 - 0.2 12.1 0.3 0.58 10.6 0.3 1.8 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Utp21 PF04192.12 RUS88535.1 - 0.36 10.3 20.6 42 3.5 0.1 9.0 11 0 0 11 11 11 0 Utp21 specific WD40 associated putative domain T6SS_VipA PF05591.12 RUS88535.1 - 0.59 9.9 28.6 68 3.2 0.1 9.8 11 0 0 11 11 11 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 YdjO PF14169.6 RUS88535.1 - 1.5 8.6 32.2 13 5.6 0.2 11.1 12 0 0 12 12 12 0 Cold-inducible protein YdjO Arfaptin PF06456.13 RUS88536.1 - 4.6e-78 261.9 4.3 6.5e-78 261.4 4.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.24 RUS88536.1 - 1.8e-11 44.2 0.2 3.4e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS88536.1 - 1.6e-10 40.6 0.9 1.3e-09 37.8 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS88536.1 - 2.5e-08 34.1 0.0 6.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain BAR PF03114.18 RUS88536.1 - 2.7e-06 27.2 2.5 9.3e-06 25.5 2.5 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RUS88536.1 - 0.00021 21.1 1.2 0.0064 16.2 1.2 2.2 1 1 0 1 1 1 1 BAR domain of APPL family DUF3929 PF13066.6 RUS88536.1 - 0.056 13.5 0.1 0.31 11.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3929) GRASP55_65 PF04495.14 RUS88536.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain SPRY PF00622.28 RUS88537.1 - 8.8e-20 71.0 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 RUS88537.1 - 6.6e-05 23.2 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 SOCS box ECF_trnsprt PF12822.7 RUS88538.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 ECF transporter, substrate-specific component ABC2_membrane_3 PF12698.7 RUS88539.1 - 0.055 12.6 0.3 0.055 12.6 0.3 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein SRTM1 PF15872.5 RUS88539.1 - 0.17 12.0 0.6 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 ABC_tran PF00005.27 RUS88540.1 - 1.1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RPA_interact_N PF14766.6 RUS88540.1 - 0.071 12.7 0.5 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal ABC2_membrane_3 PF12698.7 RUS88540.1 - 2.4 7.2 16.3 3.5 6.6 16.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 RUS88542.1 - 1.2e-20 73.4 22.5 0.0037 18.1 0.5 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS88542.1 - 4.4e-08 33.3 4.0 0.11 12.8 0.4 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS88542.1 - 0.01 14.8 0.7 0.51 9.2 0.0 2.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Patatin PF01734.22 RUS88543.1 - 3.3e-27 96.0 0.0 6.5e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Colipase-like PF15083.6 RUS88545.1 - 0.068 13.3 4.6 0.19 11.9 1.0 2.1 1 1 1 2 2 2 0 Colipase-like NiFe_hyd_SSU_C PF14720.6 RUS88545.1 - 0.13 12.7 3.3 4.3 7.8 0.8 2.3 1 1 1 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Microvir_lysis PF04517.12 RUS88545.1 - 1.7 8.6 8.9 4.3 7.4 0.4 2.3 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Cullin PF00888.22 RUS88549.1 - 2.4e-223 743.2 15.2 3.4e-223 742.8 15.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RUS88549.1 - 1.1e-25 89.4 0.3 4e-25 87.6 0.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Glyco_hydro_4C PF11975.8 RUS88549.1 - 5.2 7.1 8.4 1.5 8.8 1.6 3.0 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain HTH_32 PF13565.6 RUS88550.1 - 0.00017 22.1 0.1 0.00034 21.2 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 RUS88550.1 - 0.00033 20.8 0.1 0.00055 20.1 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_48 PF17906.1 RUS88550.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS88550.1 - 0.0045 16.9 0.1 0.0062 16.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) DUF4817 PF16087.5 RUS88550.1 - 0.01 15.6 0.2 0.065 13.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HTH_24 PF13412.6 RUS88550.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 RUS88550.1 - 0.015 15.1 0.8 2.4 8.1 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain PCI PF01399.27 RUS88550.1 - 0.017 15.6 0.0 0.026 15.0 0.0 1.4 1 1 0 1 1 1 0 PCI domain HTH_26 PF13443.6 RUS88550.1 - 0.027 14.9 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 RUS88550.1 - 0.047 13.1 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 RUS88550.1 - 0.083 12.9 0.0 6.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 RUS88550.1 - 0.098 12.8 0.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 RUS88550.1 - 0.19 11.6 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.32 RUS88552.1 - 2.2e-16 59.9 4.9 2.1e-06 28.3 0.3 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat SH3_1 PF00018.28 RUS88552.1 - 6.5e-16 57.7 0.1 1.8e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS88552.1 - 1.1e-11 44.4 0.1 2.7e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS88552.1 - 2.2e-11 43.3 0.0 5.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain ANAPC4_WD40 PF12894.7 RUS88552.1 - 1.4e-08 34.9 0.0 1.2 9.5 0.0 5.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RUS88552.1 - 0.035 12.8 0.3 6.7 5.2 0.4 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RUS88552.1 - 0.062 12.3 0.2 8 5.3 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 RUS88554.1 - 4.4e-50 168.2 24.5 4.6e-13 49.6 1.1 5.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS88554.1 - 5.1e-41 138.5 17.1 2.3e-11 44.0 0.2 8.2 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88554.1 - 4.8e-38 124.8 25.8 1.4e-05 25.1 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 RUS88554.1 - 2.8e-32 110.3 29.0 6.5e-10 39.1 1.8 9.0 2 1 9 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 RUS88554.1 - 4.8e-30 102.7 48.4 1.3e-05 25.4 0.0 10.9 10 1 0 10 10 10 9 Ankyrin repeat LRR_9 PF14580.6 RUS88555.1 - 0.00016 21.2 7.8 0.00039 20.0 0.4 3.8 4 1 0 4 4 4 1 Leucine-rich repeat LRR_4 PF12799.7 RUS88555.1 - 0.034 14.6 0.1 0.034 14.6 0.1 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS88555.1 - 0.1 12.4 8.0 0.25 11.1 1.5 3.6 2 1 2 4 4 4 0 Leucine rich repeat Annexin PF00191.20 RUS88556.1 - 1.5e-87 287.6 9.8 3.3e-22 78.3 0.5 4.0 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 RUS88556.1 - 0.00014 21.7 0.2 0.59 10.1 0.1 2.8 3 0 0 3 3 3 2 Myb DNA-binding like DUF3574 PF12098.8 RUS88556.1 - 0.0011 18.8 0.2 2.2 8.1 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3574) DUF2255 PF10012.9 RUS88556.1 - 0.0041 17.3 0.3 0.58 10.3 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2255) HTH_15 PF12324.8 RUS88556.1 - 0.019 14.9 0.7 0.24 11.4 0.9 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF2634 PF10934.8 RUS88556.1 - 0.034 14.2 1.0 3 8.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2634) SAM_Exu PF18609.1 RUS88556.1 - 0.078 13.1 0.3 0.73 10.0 0.0 2.5 2 0 0 2 2 2 0 Exuperantia SAM-like domain Acetyltransf_11 PF13720.6 RUS88556.1 - 0.15 12.6 0.4 42 4.7 0.0 3.3 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FeoB_Cyto PF17910.1 RUS88556.1 - 1.3 9.6 7.4 3.6 8.2 0.2 3.2 4 0 0 4 4 4 0 FeoB cytosolic helical domain Nucleic_acid_bd PF13820.6 RUS88557.1 - 4.3e-28 98.0 0.1 1.3e-27 96.4 0.1 1.8 1 0 0 1 1 1 1 Putative nucleic acid-binding region U3_snoRNA_assoc PF08297.11 RUS88557.1 - 0.07 13.8 3.6 0.16 12.7 0.5 3.3 2 0 0 2 2 2 0 U3 snoRNA associated PNK3P PF08645.11 RUS88558.1 - 2.8e-55 186.4 0.3 4.3e-55 185.8 0.3 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 RUS88558.1 - 3.9e-21 75.7 0.0 2.8e-11 43.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RUS88558.1 - 2.4e-05 23.7 0.0 0.12 11.7 0.0 2.4 1 1 0 2 2 2 2 Zeta toxin KTI12 PF08433.10 RUS88558.1 - 0.00012 21.7 0.1 0.099 12.1 0.0 2.2 1 1 0 2 2 2 2 Chromatin associated protein KTI12 6PF2K PF01591.18 RUS88558.1 - 0.0028 17.0 0.0 0.16 11.2 0.0 2.3 1 1 1 2 2 2 1 6-phosphofructo-2-kinase AAA_22 PF13401.6 RUS88558.1 - 0.026 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain LNS2 PF08235.13 RUS88558.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Hydrolase_6 PF13344.6 RUS88558.1 - 0.06 13.5 0.0 0.73 10.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LZ3wCH PF18517.1 RUS88558.1 - 0.08 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain NDUF_B7 PF05676.13 RUS88559.1 - 4.7e-21 74.3 8.1 6.5e-21 73.8 8.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RUS88559.1 - 0.011 15.7 8.9 0.021 14.8 8.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4377 PF14302.6 RUS88559.1 - 0.021 14.9 0.6 0.03 14.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) CHCH PF06747.13 RUS88559.1 - 0.15 12.2 5.8 4.2 7.6 1.5 2.3 2 0 0 2 2 2 0 CHCH domain ELO PF01151.18 RUS88561.1 - 1.7e-55 188.2 15.9 2e-55 188.0 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CDP-OH_P_transf PF01066.21 RUS88563.1 - 1.6e-15 57.6 0.0 1.6e-15 57.6 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SH3_2 PF07653.17 RUS88564.1 - 0.00022 20.8 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS88564.1 - 0.15 11.7 0.0 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.6 RUS88564.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF4164 PF13747.6 RUS88564.1 - 1.2 9.5 4.9 3.1 8.2 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Antistasin PF02822.14 RUS88565.1 - 5.6e-21 74.8 99.0 7.1e-06 26.6 9.1 7.5 6 2 1 7 7 7 6 Antistasin family CXCXC PF03128.14 RUS88565.1 - 2.1 9.0 0.1 2.1 9.0 0.1 8.2 7 1 0 7 7 7 0 CXCXC repeat Ras PF00071.22 RUS88566.1 - 4.6e-34 117.4 0.0 5.6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS88566.1 - 2.6e-19 69.6 0.0 4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS88566.1 - 4.8e-08 32.7 0.0 7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RUS88566.1 - 0.00026 20.3 0.3 0.45 9.6 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 RUS88566.1 - 0.0022 17.6 1.5 0.1 12.1 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS88566.1 - 0.0062 16.6 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS88566.1 - 0.009 15.5 0.0 0.017 14.6 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TniB PF05621.11 RUS88566.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 RUS88566.1 - 0.096 12.4 0.2 0.39 10.4 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PAN_1 PF00024.26 RUS88567.1 - 1.5e-10 40.9 10.7 1.2e-06 28.3 1.3 2.9 2 0 0 2 2 2 2 PAN domain Ependymin PF00811.18 RUS88567.1 - 0.057 13.7 0.0 0.057 13.7 0.0 4.6 6 0 0 6 6 6 0 Ependymin PAN_4 PF14295.6 RUS88567.1 - 0.28 11.1 12.2 2.5 8.1 2.4 2.7 2 0 0 2 2 2 0 PAN domain DSPn PF14671.6 RUS88568.1 - 1.5e-62 210.2 1.8 3.8e-62 208.9 0.6 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RUS88568.1 - 1.6e-13 50.6 0.2 4.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS88568.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RUS88568.1 - 0.00029 21.0 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RUS88568.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family AP_endonuc_2 PF01261.24 RUS88570.1 - 3.3e-05 23.4 0.0 0.00014 21.4 0.0 1.8 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel DCAF15_WD40 PF14939.6 RUS88571.1 - 9.9e-60 201.9 0.1 1.9e-59 200.9 0.1 1.4 1 0 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat CBM_14 PF01607.24 RUS88572.1 - 2.6e-15 56.3 16.4 8e-12 45.1 3.9 2.9 3 0 0 3 3 3 2 Chitin binding Peritrophin-A domain Pkinase PF00069.25 RUS88573.1 - 2.9e-24 85.9 0.0 5.9e-24 84.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88573.1 - 2.1e-08 33.8 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Nop14 PF04147.12 RUS88574.1 - 0.0016 16.8 33.0 0.0017 16.7 33.0 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS88574.1 - 0.014 14.8 35.5 0.016 14.7 35.5 1.2 1 0 0 1 1 1 0 SDA1 EIIBC-GUT_N PF03612.14 RUS88574.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.14 RUS88574.1 - 0.53 10.7 1.6 0.89 10.0 1.6 1.5 1 1 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 RUS88574.1 - 2.5 6.8 13.6 2.9 6.6 13.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RUS88574.1 - 8.5 5.6 32.7 10 5.4 32.7 1.2 1 0 0 1 1 1 0 BUD22 PCO_ADO PF07847.12 RUS88576.1 - 0.015 14.8 0.1 0.044 13.2 0.1 1.7 1 1 0 1 1 1 0 PCO_ADO Hamartin PF04388.12 RUS88576.1 - 3.1 6.3 13.7 4 6.0 13.7 1.1 1 0 0 1 1 1 0 Hamartin protein zf-3CxxC PF13695.6 RUS88577.1 - 0.0063 17.0 0.6 0.018 15.5 0.6 1.8 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 RUS88577.1 - 0.013 16.2 0.7 0.013 16.2 0.7 2.2 2 0 0 2 2 2 0 Zinc-binding domain DAP_B PF07930.12 RUS88577.1 - 0.071 13.1 0.4 0.071 13.1 0.4 1.6 2 0 0 2 2 2 0 D-aminopeptidase, domain B MAP17 PF15807.5 RUS88578.1 - 0.00016 21.9 3.4 0.0014 18.9 0.0 2.6 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Collectrin PF16959.5 RUS88578.1 - 0.0099 15.7 0.2 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Renal amino acid transporter TMEM72 PF16054.5 RUS88578.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 RCR PF12273.8 RUS88578.1 - 0.11 13.1 1.2 0.48 11.1 1.1 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 RUS88578.1 - 2.9 7.8 6.3 0.41 10.6 0.2 2.7 2 2 0 2 2 2 0 TMEM154 protein family DUF4062 PF13271.6 RUS88579.1 - 0.035 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) QSregVF PF13652.6 RUS88579.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor AAA_16 PF13191.6 RUS88580.1 - 6.8e-06 26.6 0.0 2.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 RUS88580.1 - 0.00019 21.4 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.18 RUS88580.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 RUS88580.1 - 0.071 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain APAF1_C PF17908.1 RUS88580.1 - 0.08 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 APAF-1 helical domain WD40 PF00400.32 RUS88580.1 - 0.12 13.3 2.3 20 6.3 0.2 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat GLTP PF08718.11 RUS88581.1 - 5.9e-39 133.7 0.5 5.9e-39 133.7 0.5 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) CDC45 PF02724.14 RUS88582.1 - 1 7.6 13.0 1.9 6.7 13.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Radial_spoke_3 PF06098.11 RUS88582.1 - 3.4 6.9 22.0 0.039 13.2 13.0 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 PA26 PF04636.13 RUS88582.1 - 3.5 6.4 6.1 7.4 5.4 6.1 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DHHC PF01529.20 RUS88583.1 - 4.6e-32 110.9 16.2 4.6e-32 110.9 16.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 RUS88583.1 - 0.1 12.5 1.3 0.18 11.7 1.3 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily TPD PF14811.6 RUS88583.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif MFS_1 PF07690.16 RUS88584.1 - 1.2e-48 165.9 30.2 1.2e-48 165.9 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 RUS88586.1 - 4.4e-47 160.5 0.0 6.4e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS88586.1 - 7.7e-45 153.3 0.0 1.4e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 RUS88586.1 - 6.2e-08 32.2 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS88586.1 - 2.1e-06 26.8 0.0 4.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS88586.1 - 1e-05 25.6 0.0 0.026 14.4 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Claudin_3 PF06653.11 RUS88587.1 - 5.7e-07 29.6 5.7 7e-07 29.3 5.7 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RUS88587.1 - 2.7e-05 24.0 13.4 0.0035 17.1 13.4 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS88587.1 - 0.028 14.3 8.9 0.099 12.5 8.4 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Peptidase_U4 PF03419.13 RUS88587.1 - 0.042 13.1 6.5 0.054 12.8 6.5 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Histone PF00125.24 RUS88590.1 - 0.00019 21.8 2.4 0.0003 21.2 2.3 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RUS88590.1 - 0.0032 17.7 1.0 0.0032 17.7 1.0 1.9 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FKBP_N PF01346.18 RUS88590.1 - 0.13 13.3 1.5 1.5 9.9 1.5 2.2 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 7tm_1 PF00001.21 RUS88591.1 - 4.1e-64 216.5 21.2 5.2e-64 216.1 21.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS88591.1 - 9.4e-09 35.0 22.6 1.3e-08 34.5 22.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Piezo_RRas_bdg PF12166.8 RUS88591.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Spore_III_AB PF09548.10 RUS88591.1 - 0.19 11.9 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) 7TM_GPCR_Srx PF10328.9 RUS88591.1 - 0.26 10.9 26.0 0.46 10.1 25.5 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PMT_4TMC PF16192.5 RUS88591.1 - 7 6.2 16.1 4 7.0 4.1 2.9 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase LIM_bind PF01803.16 RUS88594.1 - 1.6e-54 185.0 3.2 2.1e-42 145.3 0.4 2.3 1 1 1 2 2 2 2 LIM-domain binding protein LID PF17916.1 RUS88594.1 - 1.1e-17 63.4 2.3 3.7e-17 61.7 2.3 2.1 1 0 0 1 1 1 1 LIM interaction domain (LID) Med19 PF10278.9 RUS88595.1 - 0.079 12.9 8.6 0.12 12.3 8.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CCDC106 PF15794.5 RUS88595.1 - 0.08 12.6 5.0 0.098 12.3 5.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Peptidase_S49_N PF08496.10 RUS88595.1 - 0.097 12.7 2.2 0.11 12.5 2.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.9 RUS88595.1 - 0.099 12.2 11.2 0.13 11.9 11.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4604 PF15377.6 RUS88595.1 - 0.16 12.4 8.1 0.19 12.1 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AP3D1 PF06375.11 RUS88595.1 - 0.24 11.6 9.7 0.32 11.2 9.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FGF-BP1 PF06473.12 RUS88595.1 - 0.35 10.7 7.6 0.43 10.4 7.6 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TSGP1 PF07771.11 RUS88595.1 - 0.52 10.5 6.3 0.72 10.0 6.3 1.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 SPRY PF00622.28 RUS88597.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 2 0 0 2 2 2 0 SPRY domain SASA PF03629.18 RUS88598.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase 7tm_1 PF00001.21 RUS88599.1 - 1.9e-36 125.7 6.8 2.4e-36 125.4 6.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS88599.1 - 5.1e-10 39.5 7.2 5.3e-09 36.2 4.5 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS88599.1 - 5.3e-09 36.1 5.9 5.3e-09 36.1 5.9 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS88599.1 - 3.7e-08 33.1 8.6 9.4e-08 31.7 8.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS88599.1 - 0.0017 17.7 15.7 0.014 14.7 9.0 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srab PF10292.9 RUS88599.1 - 0.0077 15.2 0.1 0.022 13.7 0.1 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Neur_chan_LBD PF02931.23 RUS88600.1 - 2e-44 151.6 7.2 9.8e-44 149.4 7.2 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS88600.1 - 1e-29 104.3 13.0 2.2e-29 103.2 7.4 2.9 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.20 RUS88600.1 - 0.021 13.2 0.1 1.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Orf78 PF06024.12 RUS88600.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Alpha_GJ PF03229.13 RUS88602.1 - 0.42 11.2 2.9 1.3 9.6 2.9 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J Utp14 PF04615.13 RUS88603.1 - 0.00019 20.2 48.8 0.00024 19.9 48.8 1.1 1 0 0 1 1 1 1 Utp14 protein AAA_23 PF13476.6 RUS88603.1 - 0.00023 21.7 35.9 0.001 19.6 10.1 2.1 2 0 0 2 2 2 2 AAA domain Connexin PF00029.19 RUS88603.1 - 0.0013 18.6 34.3 0.0042 16.9 9.5 2.1 2 0 0 2 2 2 2 Connexin SpoIIP PF07454.11 RUS88603.1 - 0.052 13.0 40.8 0.13 11.7 14.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF1764 PF08576.10 RUS88603.1 - 0.18 12.7 59.6 1.6 9.7 25.9 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RNA_pol_Rpc4 PF05132.14 RUS88603.1 - 0.3 11.5 44.9 0.48 10.9 18.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nop53 PF07767.11 RUS88603.1 - 5 6.4 69.7 0.33 10.3 25.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Afi1 PF07792.12 RUS88603.1 - 8.9 6.8 32.4 1.2 9.6 8.3 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sugar_tr PF00083.24 RUS88604.1 - 7e-111 371.3 30.0 1.4e-84 284.6 13.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS88604.1 - 1.2e-32 113.3 35.5 8.4e-31 107.2 22.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 RUS88604.1 - 3.1e-08 32.6 18.9 3.2e-05 22.7 0.5 3.5 3 0 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.13 RUS88604.1 - 6e-05 21.7 2.4 0.00011 20.8 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAP PF07174.11 RUS88604.1 - 0.22 10.9 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Usp PF00582.26 RUS88605.1 - 5.7e-28 98.2 0.0 7e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family OCRE PF17780.1 RUS88606.1 - 1.9 8.6 5.3 18 5.5 0.1 3.1 3 0 0 3 3 3 0 OCRE domain Usp PF00582.26 RUS88607.1 - 1e-09 39.0 1.1 5.7e-09 36.6 0.2 1.9 1 1 1 2 2 2 1 Universal stress protein family Fumerase PF05681.14 RUS88607.1 - 0.064 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Ank_2 PF12796.7 RUS88608.1 - 1.1e-27 96.4 2.6 1.8e-12 47.7 0.1 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS88608.1 - 1.4e-27 92.6 3.5 1.1e-06 28.4 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 RUS88608.1 - 2.4e-27 95.0 3.0 3.8e-08 33.7 0.4 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS88608.1 - 4.7e-26 90.5 5.1 7.6e-07 29.3 0.3 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS88608.1 - 5.7e-25 86.6 9.2 6.2e-05 23.3 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat SOCS_box PF07525.16 RUS88608.1 - 1.3e-08 35.0 3.1 1.3e-08 35.0 3.1 2.2 2 0 0 2 2 2 1 SOCS box WD40 PF00400.32 RUS88609.1 - 4.1e-36 122.4 15.0 3.6e-07 30.8 0.8 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS88609.1 - 3.8e-16 59.2 0.2 3.1e-05 24.2 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS88609.1 - 8e-13 48.0 3.0 0.0042 16.1 0.1 3.8 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 RUS88609.1 - 8.6e-12 44.5 0.2 1.7e-11 43.6 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 RUS88609.1 - 3.7e-07 29.2 0.1 0.19 10.3 0.0 3.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Hira PF07569.11 RUS88609.1 - 0.0072 16.1 0.3 11 5.7 0.0 4.3 5 0 0 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.12 RUS88609.1 - 0.0086 16.0 0.0 0.47 10.4 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 RUS88609.1 - 0.052 12.5 0.2 1.5 7.7 0.0 3.0 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RT_RNaseH_2 PF17919.1 RUS88610.1 - 4e-34 116.7 0.0 6.9e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS88610.1 - 1.4e-33 115.3 0.0 2.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 RUS88610.1 - 6.1e-13 48.7 0.1 1.3e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Mgr1 PF08602.10 RUS88610.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PHD PF00628.29 RUS88611.1 - 6e-09 35.7 10.7 2.3e-08 33.8 10.7 2.1 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 RUS88611.1 - 4.3e-07 30.5 10.0 8.5e-07 29.5 0.0 4.1 4 0 0 4 4 4 1 SET domain PHD_2 PF13831.6 RUS88611.1 - 0.0021 17.6 7.1 0.0055 16.2 7.1 1.7 1 0 0 1 1 1 1 PHD-finger F-112 PF09645.10 RUS88611.1 - 0.74 9.9 3.9 0.39 10.8 0.5 2.3 2 0 0 2 2 2 0 F-112 protein Mitochondr_Som1 PF11093.8 RUS88612.1 - 0.023 14.7 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF3695 PF12494.8 RUS88613.1 - 2e-31 107.8 0.4 3.4e-31 107.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) wnt PF00110.19 RUS88614.1 - 7.1e-117 390.4 23.2 7.1e-117 390.4 23.2 1.6 2 0 0 2 2 2 1 wnt family Homeodomain PF00046.29 RUS88616.1 - 1.2e-21 76.3 1.4 2.2e-21 75.5 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS88616.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 RUS88616.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 RUS88616.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez SUIM_assoc PF16619.5 RUS88616.1 - 0.18 11.9 7.6 1.1 9.4 7.6 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Polysacc_deac_1 PF01522.21 RUS88618.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase 7tm_1 PF00001.21 RUS88620.1 - 6.7e-23 81.4 0.9 9.1e-23 80.9 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS88620.1 - 0.0009 18.7 0.2 0.0012 18.3 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ABC_membrane PF00664.23 RUS88621.1 - 1.1e-36 126.9 17.6 4.4e-36 124.9 15.4 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS88621.1 - 1.4e-21 77.4 0.5 3.4e-21 76.2 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 RUS88621.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 RUS88621.1 - 0.0063 16.6 1.0 0.011 15.9 0.1 1.8 2 0 0 2 2 2 1 Dynamin family SMC_N PF02463.19 RUS88621.1 - 0.0077 15.7 3.2 0.47 9.9 2.2 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS88621.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 RUS88621.1 - 0.053 13.3 0.2 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 RUS88621.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 RUS88621.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 RUS88621.1 - 0.17 11.8 0.4 0.39 10.6 0.4 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF697 PF05128.12 RUS88622.1 - 0.053 13.2 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF2771 PF10969.8 RUS88623.1 - 0.023 14.7 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) WD40 PF00400.32 RUS88624.1 - 1.9e-14 53.8 5.9 2.5e-05 24.9 0.0 4.7 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS88624.1 - 0.0014 18.8 0.7 1.8 8.9 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RUS88624.1 - 0.017 15.1 0.0 14 5.8 0.0 3.3 2 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 RUS88625.1 - 6.6e-08 33.1 0.4 0.0029 18.4 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Trypsin_2 PF13365.6 RUS88626.1 - 0.0021 18.9 0.1 0.0041 18.0 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DSPc PF00782.20 RUS88627.1 - 2.5e-14 53.2 0.2 6.5e-14 51.9 0.2 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS88627.1 - 4.5e-09 36.2 0.6 8.5e-09 35.3 0.6 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RUS88627.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 RUS88627.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RhoGAP PF00620.27 RUS88628.1 - 0.00043 20.1 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain CN_hydrolase PF00795.22 RUS88628.1 - 0.066 12.5 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Pkinase PF00069.25 RUS88629.1 - 6.4e-27 94.6 0.0 4.3e-26 91.8 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88629.1 - 9.1e-14 51.4 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88629.1 - 0.00095 18.6 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RUS88630.1 - 4.3e-33 114.8 0.0 5.3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88630.1 - 2.2e-19 69.8 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88630.1 - 0.0027 17.1 0.2 0.0048 16.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS88630.1 - 0.037 13.6 0.5 3.7 7.1 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 RUS88631.1 - 5.9e-33 114.3 0.0 8.7e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88631.1 - 4.5e-18 65.5 0.0 5.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88631.1 - 0.0016 17.9 0.2 0.0032 16.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS88631.1 - 0.038 13.6 0.1 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MerR PF00376.23 RUS88632.1 - 9.5e-05 22.1 7.3 23 4.8 0.0 6.1 6 0 0 6 6 6 0 MerR family regulatory protein DUF2158 PF09926.9 RUS88632.1 - 0.00022 20.9 11.4 2.9 7.7 0.2 5.7 3 2 2 5 5 5 2 Uncharacterized small protein (DUF2158) Ribosomal_S27 PF01599.19 RUS88632.1 - 0.0032 17.6 8.3 16 5.8 0.0 5.2 1 1 4 6 6 6 0 Ribosomal protein S27a DUF4179 PF13786.6 RUS88632.1 - 0.0086 16.5 0.0 14 6.3 0.0 3.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4179) Abhydro_lipase PF04083.16 RUS88632.1 - 0.017 14.7 4.0 0.45 10.1 0.2 3.2 1 1 1 3 3 3 0 Partial alpha/beta-hydrolase lipase region DUF3509 PF12021.8 RUS88632.1 - 0.023 14.4 0.2 8 6.3 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3509) DUF2103 PF09876.9 RUS88632.1 - 0.035 14.1 0.1 6 6.9 0.0 2.5 1 1 2 3 3 3 0 Predicted metal-binding protein (DUF2103) Caskin1-CID PF16600.5 RUS88632.1 - 0.039 14.5 11.7 0.32 11.6 0.3 3.1 1 1 2 3 3 3 0 Caskin1 CASK-interaction domain Cation_ATPase PF13246.6 RUS88632.1 - 0.044 13.9 0.6 11 6.2 0.1 3.2 1 1 1 2 2 2 0 Cation transport ATPase (P-type) DUF3859 PF12975.7 RUS88632.1 - 0.062 13.3 0.0 38 4.3 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3859) CBM_48 PF02922.18 RUS88632.1 - 0.12 12.8 0.5 1.4 9.3 0.5 2.4 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Rio2_N PF09202.11 RUS88632.1 - 0.24 11.6 2.4 4.3 7.6 0.2 3.4 1 1 3 4 4 4 0 Rio2, N-terminal PriA_CRR PF18319.1 RUS88632.1 - 0.36 10.9 14.6 37 4.4 0.0 5.7 6 0 0 6 6 6 0 PriA DNA helicase Cys-rich region (CRR) domain MFS_1 PF07690.16 RUS88633.1 - 1.8e-05 23.9 22.3 2.5e-05 23.4 16.2 2.8 2 2 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.25 RUS88634.1 - 3.1e-33 115.3 0.0 3.8e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88634.1 - 2.6e-22 79.4 0.0 3.3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88634.1 - 0.0003 20.2 0.2 0.0005 19.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS88634.1 - 0.053 13.1 0.4 3.6 7.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RUS88634.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RUS88634.1 - 0.15 11.4 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 RUS88635.1 - 1.6e-28 99.8 0.0 2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88635.1 - 1.8e-17 63.5 0.0 2.1e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS88635.1 - 0.00083 18.8 0.2 0.0014 18.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RUS88635.1 - 0.01 15.5 0.4 1.1 8.8 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 fn3 PF00041.21 RUS88636.1 - 5.6e-34 116.3 9.1 1.1e-10 41.6 0.1 5.6 5 1 0 5 5 5 4 Fibronectin type III domain I-set PF07679.16 RUS88636.1 - 1.1e-11 44.7 0.1 2.5e-10 40.3 0.0 3.0 4 0 0 4 4 4 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS88636.1 - 1.5e-06 28.7 0.0 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS88636.1 - 3.6e-05 24.3 0.2 2.1 8.9 0.1 3.8 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain ig PF00047.25 RUS88636.1 - 0.0008 19.5 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS88636.1 - 0.0011 19.2 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Tissue_fac PF01108.17 RUS88636.1 - 0.015 15.1 5.9 2.1 8.2 0.0 3.6 4 0 0 4 4 4 0 Tissue factor BiPBP_C PF06832.12 RUS88636.1 - 0.021 14.9 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family Pentapeptide_2 PF01469.18 RUS88637.1 - 1.6e-05 24.7 0.6 2.5 8.1 0.1 3.7 1 1 4 5 5 5 5 Pentapeptide repeats (8 copies) DUF1127 PF06568.11 RUS88637.1 - 0.13 12.0 2.3 59 3.5 0.0 5.1 2 2 3 5 5 5 0 Domain of unknown function (DUF1127) DUF1495 PF07381.11 RUS88637.1 - 2.2 8.1 11.5 58 3.6 1.7 4.4 1 1 1 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Lectin_C PF00059.21 RUS88638.1 - 1.8e-14 54.3 0.1 2.9e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS88638.1 - 0.0062 16.5 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 PAN domain Chordopox_A33R PF05966.12 RUS88638.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein HTH_13 PF11972.8 RUS88638.1 - 7.9 6.6 6.1 8.2 6.6 1.6 2.9 1 1 2 3 3 3 0 HTH DNA binding domain Lectin_C PF00059.21 RUS88639.1 - 8.2e-16 58.7 0.0 1.7e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Lectin C-type domain WYL PF13280.6 RUS88639.1 - 0.081 13.0 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 WYL domain Intimin_C PF07979.11 RUS88639.1 - 0.081 13.3 1.6 0.42 11.0 0.0 2.4 2 1 1 3 3 3 0 Intimin C-type lectin domain PAN_1 PF00024.26 RUS88639.1 - 1.1 9.2 6.9 0.094 12.7 0.8 2.3 3 0 0 3 3 3 0 PAN domain fn3 PF00041.21 RUS88640.1 - 4.4e-27 94.3 3.6 2.2e-11 44.0 0.0 4.6 4 1 0 4 4 4 4 Fibronectin type III domain I-set PF07679.16 RUS88640.1 - 8.6e-06 25.7 0.2 8.8e-05 22.5 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 RUS88640.1 - 8.5e-05 22.6 0.4 0.00067 19.8 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 RUS88640.1 - 0.00032 21.2 0.2 0.015 15.9 0.0 3.3 3 1 0 3 3 3 1 Immunoglobulin domain fn3_2 PF16893.5 RUS88640.1 - 0.0011 19.1 0.0 1.6 8.9 0.0 3.2 3 0 0 3 3 3 2 Fibronectin type III domain Tissue_fac PF01108.17 RUS88640.1 - 0.0014 18.5 0.1 0.0069 16.2 0.0 2.2 3 0 0 3 3 3 1 Tissue factor V-set PF07686.17 RUS88640.1 - 0.0028 17.8 0.1 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Y_Y_Y PF07495.13 RUS88640.1 - 0.012 15.5 0.1 6.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Y_Y_Y domain Ig_2 PF13895.6 RUS88640.1 - 0.026 14.9 0.1 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 RUS88640.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Fz PF01392.22 RUS88641.1 - 2e-44 150.8 9.8 5.7e-23 81.7 3.8 2.0 2 0 0 2 2 2 2 Fz domain Glypican PF01153.19 RUS88641.1 - 0.77 8.5 12.0 0.89 8.3 2.0 2.0 2 0 0 2 2 2 0 Glypican Folate_rec PF03024.14 RUS88641.1 - 8.3 6.2 10.1 0.66 9.8 1.3 2.3 2 0 0 2 2 2 0 Folate receptor family ADH_zinc_N PF00107.26 RUS88643.1 - 1.9e-16 60.2 0.1 3.3e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 RUS88643.1 - 5.6e-16 58.4 0.0 1.9e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 RUS88643.1 - 7.2e-08 33.6 0.0 1.3e-07 32.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_C PF02080.21 RUS88643.1 - 0.12 12.2 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-C domain ADH_N PF08240.12 RUS88644.1 - 2.9e-26 91.5 2.6 6.4e-26 90.4 2.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS88644.1 - 8.8e-24 83.9 0.0 1.8e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RUS88644.1 - 1.6e-10 40.9 0.2 5e-10 39.2 0.2 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RUS88644.1 - 1.4e-05 26.1 0.0 2.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 RUS88644.1 - 0.047 12.9 0.2 0.096 11.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 RUS88644.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SOG2 PF10428.9 RUS88646.1 - 1.2 8.3 18.6 1.2 8.2 18.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nop14 PF04147.12 RUS88647.1 - 2.5e-05 22.8 32.6 3e-05 22.5 32.6 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS88647.1 - 0.016 14.7 40.6 0.02 14.3 40.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RUS88647.1 - 0.12 11.7 33.3 0.15 11.4 33.3 1.1 1 0 0 1 1 1 0 BUD22 RPA43_OB PF17875.1 RUS88647.1 - 2.1 9.0 13.1 65 4.2 12.7 2.3 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I PNISR PF15996.5 RUS88647.1 - 4.5 7.5 6.3 7.3 6.8 6.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SpoIIIAH PF12685.7 RUS88647.1 - 7 6.4 11.7 10 5.9 11.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 RUS88647.1 - 9.4 4.9 14.5 12 4.6 14.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.13 RUS88648.1 - 0.0031 17.6 36.8 0.0042 17.1 36.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Dsh_C PF12316.8 RUS88648.1 - 0.013 15.9 3.5 0.02 15.3 3.5 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Pex24p PF06398.11 RUS88648.1 - 0.38 9.7 4.5 0.49 9.3 4.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sec62 PF03839.16 RUS88648.1 - 0.38 10.2 15.1 0.62 9.5 15.1 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 MDM10 PF12519.8 RUS88648.1 - 1 8.1 4.7 0.88 8.4 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4770 PF15994.5 RUS88648.1 - 1.2 9.4 13.0 1.4 9.1 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Striatin PF08232.12 RUS88648.1 - 2 9.0 15.8 7.3 7.2 11.5 2.1 2 0 0 2 2 2 0 Striatin family MscS_TM PF12794.7 RUS88648.1 - 6.4 5.5 5.3 8.1 5.2 5.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3795 PF12675.7 RUS88648.1 - 6.9 7.1 21.3 11 6.5 21.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) ORC5_C PF14630.6 RUS88648.1 - 7.1 6.1 11.4 9.8 5.6 11.4 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF4551 PF15087.6 RUS88648.1 - 7.5 5.3 14.3 8.1 5.1 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.16 RUS88648.1 - 8.8 6.3 7.8 9.6 6.2 7.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BIR PF00653.21 RUS88649.1 - 1e-18 67.7 1.4 1.3e-18 67.4 1.4 1.1 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DALR_1 PF05746.15 RUS88650.1 - 3.1e-14 53.1 0.3 2.7e-13 50.1 0.1 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain DUF695 PF05117.12 RUS88650.1 - 0.16 12.1 0.0 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF695) Glyco_hydro_20 PF00728.22 RUS88651.1 - 4.2e-94 315.8 0.0 6.4e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain CHB_HEX PF03173.13 RUS88651.1 - 6.8e-28 97.3 0.0 2.2e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 Putative carbohydrate binding domain CHB_HEX_C PF03174.13 RUS88651.1 - 4.1e-16 58.7 0.0 1.1e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20b PF02838.15 RUS88651.1 - 1.8e-09 38.4 0.0 5e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 RUS88651.1 - 0.0015 19.2 0.3 0.0059 17.3 0.3 2.1 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Vezatin PF12632.7 RUS88652.1 - 0.087 12.2 3.1 0.08 12.3 0.6 2.1 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes Cadherin PF00028.17 RUS88653.1 - 0.0055 17.1 0.1 2.9 8.4 0.0 3.5 3 0 0 3 3 3 2 Cadherin domain Shisa PF13908.6 RUS88653.1 - 0.059 13.6 1.0 0.11 12.7 1.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.25 RUS88654.1 - 1.2e-70 237.9 0.2 1.6e-70 237.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS88654.1 - 1.1e-49 169.1 0.3 1.6e-49 168.6 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS88654.1 - 9.5e-07 27.9 0.3 1.5e-06 27.3 0.3 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RUS88654.1 - 1.5e-05 24.4 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 RUS88654.1 - 0.015 15.0 0.4 0.029 14.0 0.3 1.6 1 1 0 1 1 1 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 RUS88654.1 - 0.025 13.5 1.8 0.059 12.3 1.9 1.4 1 1 1 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 RUS88654.1 - 0.1 12.2 0.2 2.3 7.8 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FliD_N PF02465.18 RUS88656.1 - 0.1 13.3 1.9 14 6.4 0.1 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HALZ PF02183.18 RUS88656.1 - 0.11 12.7 0.5 0.27 11.5 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper SNAP PF14938.6 RUS88657.1 - 1.2e-05 24.9 1.9 2e-05 24.2 1.9 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Lig_chan PF00060.26 RUS88658.1 - 1.1e-56 190.9 0.1 1.9e-56 190.1 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 RUS88658.1 - 3.8e-45 154.5 0.0 5.4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 RUS88658.1 - 3.3e-43 146.5 0.0 9.7e-43 145.0 0.0 1.9 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS88658.1 - 6.3e-21 74.8 0.0 1.2e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peptidase_M50B PF13398.6 RUS88660.1 - 0.0019 17.9 0.8 0.0019 17.9 0.8 2.0 1 1 1 2 2 2 1 Peptidase M50B-like O-ag_pol_Wzy PF14296.6 RUS88660.1 - 0.0039 15.9 0.8 0.005 15.5 0.8 1.1 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy CitMHS PF03600.16 RUS88660.1 - 0.039 13.2 0.6 0.059 12.6 0.6 1.3 1 1 0 1 1 1 0 Citrate transporter TMEM171 PF15471.6 RUS88660.1 - 0.093 11.7 2.5 0.11 11.5 0.4 2.0 1 1 0 2 2 2 0 Transmembrane protein family 171 Fasciclin PF02469.22 RUS88661.1 - 1.7e-38 131.7 0.0 3.5e-21 75.8 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 RUS88662.1 - 7.5e-45 152.3 0.2 1.7e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain SNF PF00209.18 RUS88663.1 - 3.7e-191 636.3 20.9 1.9e-138 462.5 7.6 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family Homeodomain PF00046.29 RUS88664.1 - 5.9e-22 77.3 3.0 1e-21 76.5 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS88664.1 - 0.046 13.6 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 RUS88664.1 - 0.29 11.0 1.2 0.45 10.4 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain CPSF73-100_C PF11718.8 RUS88664.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.1 3 0 0 3 3 3 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Mucin15 PF15672.5 RUS88665.1 - 0.25 10.8 6.4 0.34 10.4 6.4 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 AMP-binding PF00501.28 RUS88666.1 - 1.3e-48 165.7 0.0 2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS88666.1 - 4.1e-08 34.1 2.1 6.1e-07 30.3 0.9 3.0 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Homeodomain PF00046.29 RUS88667.1 - 3.6e-22 78.0 4.8 7.4e-22 77.0 4.8 1.6 1 0 0 1 1 1 1 Homeodomain DUF4551 PF15087.6 RUS88667.1 - 1.7 7.4 11.5 2.2 7.0 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SNF PF00209.18 RUS88668.1 - 3.7e-107 359.2 37.3 9.4e-107 357.9 37.3 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Tubulin PF00091.25 RUS88669.1 - 3.1e-68 229.8 0.0 5.3e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS88669.1 - 1e-42 145.2 0.1 1.6e-42 144.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RUS88669.1 - 4.3e-05 23.8 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RUS88669.1 - 0.014 14.7 0.0 0.038 13.2 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Tubulin_3 PF14881.6 RUS88669.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Lipocalin_2 PF08212.12 RUS88671.1 - 6.3e-05 22.9 0.0 7.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain EGF PF00008.27 RUS88672.1 - 2.5e-21 75.6 86.2 1.9e-07 31.2 4.9 8.1 8 1 0 8 8 8 6 EGF-like domain EGF_2 PF07974.13 RUS88672.1 - 9.3e-14 51.5 104.2 0.0025 18.1 7.4 7.6 7 0 0 7 7 7 7 EGF-like domain DSL PF01414.19 RUS88672.1 - 3.4e-11 43.2 76.0 5.7e-11 42.5 5.6 6.2 5 2 1 6 6 6 4 Delta serrate ligand hEGF PF12661.7 RUS88672.1 - 3.9e-05 24.1 80.2 0.00029 21.4 4.6 8.9 8 2 1 9 9 9 4 Human growth factor-like EGF Laminin_EGF PF00053.24 RUS88672.1 - 0.0033 17.5 81.2 0.059 13.5 6.8 7.4 2 1 5 7 7 7 4 Laminin EGF domain EGF_CA PF07645.15 RUS88672.1 - 0.019 15.2 5.1 0.019 15.2 5.1 8.3 3 2 4 7 7 7 0 Calcium-binding EGF domain Peptidase_S10 PF00450.22 RUS88673.1 - 9.7e-64 216.3 3.8 4.9e-43 148.1 0.2 2.5 1 1 1 2 2 2 2 Serine carboxypeptidase Acyltransf_C PF16076.5 RUS88674.1 - 1.8e-23 82.4 0.0 3.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 RUS88674.1 - 9.8e-14 51.1 0.0 1.8e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RUS88675.1 - 1.1e-20 73.5 0.2 2.1e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 RUS88675.1 - 2.7e-13 49.7 0.0 5.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase YhdB PF14148.6 RUS88675.1 - 0.018 15.1 0.4 0.53 10.4 0.0 2.9 3 0 0 3 3 3 0 YhdB-like protein DUF2721 PF11026.8 RUS88675.1 - 0.03 14.2 2.7 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RunxI PF08504.11 RUS88676.1 - 0.16 12.7 0.1 0.16 12.7 0.1 2.5 2 0 0 2 2 2 0 Runx inhibition domain PVL_ORF50 PF07768.11 RUS88676.1 - 6.3 7.2 6.6 5.8 7.3 0.5 2.6 2 0 0 2 2 2 0 PVL ORF-50-like family Toxin_9 PF02819.15 RUS88677.1 - 0.0036 17.6 15.4 0.006 16.8 15.1 1.6 1 1 0 1 1 1 1 Spider toxin Zn-C2H2_12 PF18112.1 RUS88679.1 - 0.0075 16.7 1.1 0.16 12.4 0.7 3.2 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 RUS88679.1 - 0.019 15.4 0.8 0.019 15.4 0.8 5.0 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS88679.1 - 0.053 14.4 0.8 0.053 14.4 0.8 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger DUF572 PF04502.13 RUS88681.1 - 2.1 7.9 10.4 5.9 6.4 8.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pyr_redox_2 PF07992.14 RUS88682.1 - 2.6e-13 49.9 0.0 5.6e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RUS88682.1 - 0.0013 18.2 1.4 0.72 9.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 RUS88682.1 - 0.0025 18.3 0.4 0.018 15.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RUS88682.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 RUS88682.1 - 0.037 13.1 0.3 0.059 12.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 RUS88682.1 - 0.044 14.0 0.1 0.15 12.3 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 RUS88682.1 - 0.062 12.5 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.32 RUS88683.1 - 1.4e-09 38.4 10.5 0.00018 22.2 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 RUS88683.1 - 4.7e-05 22.2 0.5 0.00037 19.3 0.1 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RUS88683.1 - 0.0014 18.9 0.2 10 6.5 0.0 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M16_M PF16187.5 RUS88685.1 - 2.6e-35 122.1 0.8 4.4e-35 121.4 0.8 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RUS88685.1 - 2.9e-05 24.2 0.0 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Rpr2 PF04032.16 RUS88685.1 - 0.033 14.5 0.1 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PP2C PF00481.21 RUS88689.1 - 2.3e-57 194.6 0.1 3.1e-57 194.1 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS88689.1 - 3.1e-05 23.7 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C YlaC PF10777.9 RUS88690.1 - 0.12 12.2 0.0 10 5.9 0.0 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC Pkinase_Tyr PF07714.17 RUS88691.1 - 1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS88691.1 - 3.1e-30 105.4 0.0 4.6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 RUS88691.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NPDC1 PF06809.11 RUS88691.1 - 0.23 10.5 3.7 0.093 11.8 0.7 1.8 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) PHD_3 PF13922.6 RUS88691.1 - 1.9 8.9 11.3 1.6 9.1 5.3 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx 7tm_1 PF00001.21 RUS88692.1 - 0.0011 18.3 8.1 0.041 13.2 0.8 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) COA2 PF17051.5 RUS88692.1 - 0.24 11.5 0.8 0.49 10.5 0.0 1.9 2 1 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 DUF3328 PF11807.8 RUS88693.1 - 0.019 14.7 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) EB PF01683.18 RUS88693.1 - 0.44 10.9 5.7 1 9.7 5.7 1.6 1 0 0 1 1 1 0 EB module Fer4_3 PF12798.7 RUS88693.1 - 7.7 7.7 7.0 3.4 8.8 1.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Gal-3-0_sulfotr PF06990.11 RUS88694.1 - 3.3e-54 184.3 0.4 3.9e-54 184.1 0.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS88694.1 - 6.5e-05 23.0 0.7 9.6e-05 22.4 0.7 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF4362 PF14275.6 RUS88694.1 - 0.071 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) Chitin_synth_2 PF03142.15 RUS88695.1 - 4.7e-07 28.8 0.0 0.00019 20.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 RUS88695.1 - 9.3e-06 25.5 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 TMCO5 PF14992.6 RUS88695.1 - 0.12 11.9 0.1 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 TMCO5 family Glyco_trans_2_3 PF13632.6 RUS88695.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.1 2 1 0 2 2 2 0 Glycosyl transferase family group 2 SAM_1 PF00536.30 RUS88696.1 - 4.3e-18 65.5 0.1 1.4e-10 41.4 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS88696.1 - 7.7e-18 64.4 0.8 3.7e-08 33.4 0.1 3.0 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) DUF21 PF01595.20 RUS88696.1 - 0.0051 16.5 0.5 0.0081 15.9 0.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain PDEase_I_N PF08499.12 RUS88696.1 - 0.014 15.2 0.5 6.3 6.7 0.4 2.7 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Gal-3-0_sulfotr PF06990.11 RUS88697.1 - 3e-55 187.7 1.8 4.1e-55 187.3 1.8 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS88697.1 - 0.00025 21.1 0.9 0.00041 20.3 0.9 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF4362 PF14275.6 RUS88697.1 - 0.083 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) UbiA PF01040.18 RUS88698.1 - 3.1e-32 111.8 14.9 4.2e-32 111.4 14.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Transposase_1 PF01359.18 RUS88698.1 - 6.3e-18 64.4 0.1 1.2e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS88698.1 - 1.3e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 RUS88698.1 - 0.00013 22.1 0.2 0.00028 21.1 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 RUS88698.1 - 0.0018 18.8 0.1 0.0066 17.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 RUS88698.1 - 0.0043 17.1 0.4 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DUF977 PF06163.11 RUS88698.1 - 0.04 13.9 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_24 PF13412.6 RUS88698.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UbiA PF01040.18 RUS88699.1 - 7.3e-33 113.9 15.9 9.3e-33 113.6 15.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_hydro_79n PF03662.14 RUS88700.1 - 4.9e-19 68.4 0.2 8.2e-19 67.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain VWC PF00093.18 RUS88702.1 - 1.8e-14 53.8 21.6 4.7e-12 46.0 16.9 2.3 2 0 0 2 2 2 2 von Willebrand factor type C domain Amnionless PF14828.6 RUS88702.1 - 0.0023 16.8 11.9 0.0037 16.2 11.9 1.2 1 0 0 1 1 1 1 Amnionless VWC PF00093.18 RUS88703.1 - 1.8e-12 47.3 43.8 2.5e-09 37.3 12.3 4.0 4 0 0 4 4 4 3 von Willebrand factor type C domain Rad50_zn_hook PF04423.14 RUS88703.1 - 0.21 11.4 7.9 2.3 8.1 0.6 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Peptidase_M10 PF00413.24 RUS88704.1 - 1.6e-31 109.3 0.0 3.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 RUS88704.1 - 9.2e-16 57.5 22.7 4.4e-05 23.3 1.2 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.18 RUS88704.1 - 4.3e-06 26.8 0.0 9.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 RUS88704.1 - 0.0027 17.4 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Retrotrans_gag PF03732.17 RUS88704.1 - 0.0044 17.3 0.7 0.014 15.7 0.7 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Metallopep PF12044.8 RUS88704.1 - 0.0099 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.9 RUS88704.1 - 0.044 12.7 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 RUS88704.1 - 0.075 12.2 0.2 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 RUS88704.1 - 0.11 13.1 0.2 0.3 11.6 0.2 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS88704.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like IL5 PF02025.15 RUS88704.1 - 0.18 12.1 1.7 0.3 11.4 1.7 1.3 1 0 0 1 1 1 0 Interleukin 5 DUF3810 PF12725.7 RUS88704.1 - 0.31 10.4 1.1 1.7 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) VP_N-CPKC PF11475.8 RUS88705.1 - 0.041 13.8 5.4 2.2 8.3 0.6 2.3 1 1 1 2 2 2 0 Virion protein N terminal domain AKAP28 PF14469.6 RUS88705.1 - 0.068 12.9 22.7 1.8 8.4 0.0 6.5 1 1 5 6 6 6 0 28 kDa A-kinase anchor Reeler PF02014.16 RUS88706.1 - 4.9e-09 37.0 0.0 9.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Reeler domain Asp_protease PF09668.10 RUS88707.1 - 4.6e-60 200.9 1.1 6.6e-60 200.3 1.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS88707.1 - 3.8e-26 91.5 0.0 8.7e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 RUS88707.1 - 1.7e-13 50.1 0.0 3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 RUS88707.1 - 4.6e-10 40.0 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 RUS88707.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 RUS88707.1 - 5.7e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 RUS88707.1 - 8.2e-06 25.6 0.5 8.2e-06 25.6 0.5 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 RUS88707.1 - 0.0022 17.8 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like T2SSE_N PF05157.15 RUS88707.1 - 0.022 15.0 0.4 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Ubiquitin_4 PF18036.1 RUS88707.1 - 0.075 13.1 0.0 2.1 8.4 0.0 2.6 1 1 1 2 2 2 0 Ubiquitin-like domain COesterase PF00135.28 RUS88708.1 - 2e-16 60.0 0.0 2.3e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 RUS88709.1 - 6.3e-52 177.1 0.6 6.9e-52 177.0 0.6 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS88709.1 - 1.1e-11 45.0 0.3 5.2e-11 42.8 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS88709.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS88709.1 - 0.15 12.7 0.1 0.18 12.4 0.1 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4943 PF16301.5 RUS88709.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) TRAP-gamma PF07074.12 RUS88710.1 - 9.7e-87 288.9 7.1 1.1e-86 288.7 7.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Peptidase_M3_N PF08439.10 RUS88710.1 - 0.035 14.4 1.1 8.2 6.8 0.2 2.3 2 0 0 2 2 2 0 Oligopeptidase F ATP_synt_H PF05493.13 RUS88710.1 - 0.087 13.3 3.3 0.72 10.4 0.1 2.9 3 0 0 3 3 3 0 ATP synthase subunit H YoaP PF14268.6 RUS88710.1 - 0.45 10.0 2.5 3.4 7.2 0.9 2.4 2 0 0 2 2 2 0 YoaP-like SieB PF14163.6 RUS88710.1 - 0.66 9.5 7.7 2.1 7.8 0.4 2.6 3 0 0 3 3 3 0 Super-infection exclusion protein B RVT_1 PF00078.27 RUS88711.1 - 7.8e-27 94.2 0.0 1.2e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS88711.1 - 4.3e-15 56.1 0.1 1.2e-13 51.5 0.1 2.3 1 1 0 1 1 1 1 RNase H Fzo_mitofusin PF04799.13 RUS88712.1 - 0.034 13.7 4.7 0.55 9.8 0.2 2.4 3 0 0 3 3 3 0 fzo-like conserved region CHDCT2 PF08074.11 RUS88712.1 - 0.037 14.2 0.3 8.3 6.6 0.0 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain MbeD_MobD PF04899.12 RUS88712.1 - 0.037 14.1 4.1 1.2 9.3 0.6 2.9 2 1 0 2 2 2 0 MbeD/MobD like DUF4407 PF14362.6 RUS88712.1 - 0.23 10.8 4.4 0.3 10.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4164 PF13747.6 RUS88712.1 - 1.8 8.9 11.8 0.15 12.4 3.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 RUS88712.1 - 3.3 8.2 12.5 6.4 7.3 6.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Ion_trans PF00520.31 RUS88713.1 - 2.7e-21 75.9 15.9 8.7e-12 44.8 2.8 2.4 2 0 0 2 2 2 2 Ion transport protein TRP_2 PF08344.11 RUS88713.1 - 2.8e-21 75.5 1.2 5.2e-21 74.6 0.3 2.0 3 0 0 3 3 3 1 Transient receptor ion channel II PKD_channel PF08016.12 RUS88713.1 - 7e-05 21.7 13.8 0.019 13.7 4.0 2.4 2 0 0 2 2 2 2 Polycystin cation channel DUF4184 PF13803.6 RUS88713.1 - 0.017 14.8 1.2 0.042 13.5 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) DUF373 PF04123.13 RUS88713.1 - 0.17 11.3 6.5 0.15 11.5 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) OAM_alpha PF16552.5 RUS88714.1 - 0.86 9.5 3.3 0.7 9.8 2.3 1.5 1 1 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit HgmA PF04209.13 RUS88714.1 - 8.1 5.0 6.4 1.8 7.2 2.4 1.7 1 1 0 2 2 2 0 homogentisate 1,2-dioxygenase Crisp PF08562.10 RUS88715.1 - 2.2e-05 25.0 12.6 0.72 10.5 0.8 4.2 2 2 2 4 4 4 4 Crisp Paramecium_SA PF01508.16 RUS88715.1 - 0.64 10.5 10.7 4.9 7.6 2.5 3.4 2 2 0 2 2 2 0 Paramecium surface antigen domain DUF4573 PF15140.6 RUS88715.1 - 1.3 8.8 25.4 2.5 7.8 25.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) ATP-synt_S1 PF05827.12 RUS88716.1 - 4.9e-07 29.7 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.17 RUS88716.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) PH PF00169.29 RUS88717.1 - 5.1e-09 36.6 0.0 2.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 PH domain RUN PF02759.19 RUS88718.1 - 2.8e-16 59.7 0.9 8.7e-16 58.1 0.9 1.9 1 1 0 1 1 1 1 RUN domain PMP22_Claudin PF00822.20 RUS88719.1 - 0.0012 18.7 0.1 0.0016 18.4 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM37 PF15108.6 RUS88719.1 - 0.0025 17.7 0.1 0.0028 17.6 0.1 1.1 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family DUF4744 PF15918.5 RUS88720.1 - 2.6e-07 31.4 26.7 5.5 7.9 0.1 8.5 3 1 7 10 10 10 8 Domain of unknown function (DUF4744) Sec34 PF04136.15 RUS88720.1 - 0.00012 22.0 0.5 41 4.0 0.0 4.6 1 1 3 5 5 5 3 Sec34-like family DUF1664 PF07889.12 RUS88720.1 - 0.00035 20.6 6.6 11 6.1 1.9 5.0 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) Flp1_like PF16982.5 RUS88721.1 - 1.6e-05 24.2 0.1 1.5e+02 1.9 0.0 7.1 8 0 0 8 8 8 0 Putative Flagellin, Flp1-like, domain DUF5032 PF16435.5 RUS88721.1 - 0.0065 16.0 1.0 39 3.6 0.0 3.8 1 1 4 5 5 5 4 Domain of unknown function (DUF5032) CDC24_OB1 PF17246.2 RUS88721.1 - 0.032 14.4 10.4 20 5.3 0.3 5.1 1 1 4 5 5 5 0 Cell division control protein 24, OB domain 1 Copine PF07002.16 RUS88722.1 - 4e-51 173.6 0.0 6.2e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 RUS88722.1 - 3.8e-05 23.9 0.0 6.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus SCO1-SenC PF02630.14 RUS88723.1 - 6.6e-48 162.0 0.0 9e-48 161.6 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RUS88723.1 - 2.2e-06 27.6 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RUS88723.1 - 0.021 15.2 0.0 0.07 13.5 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like DUF4366 PF14283.6 RUS88723.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) eIF-5a PF01287.20 RUS88724.1 - 1.1e-26 92.7 2.9 1.5e-26 92.3 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RUS88724.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 1.8 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain PDZ PF00595.24 RUS88725.1 - 2.4e-11 43.8 0.0 3.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS88725.1 - 1.7e-06 27.8 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS88725.1 - 0.00013 22.2 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GARS_A PF01071.19 RUS88726.1 - 6.6e-85 283.8 0.1 1.4e-84 282.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 RUS88726.1 - 1.7e-39 135.5 2.9 1.2e-32 113.2 0.0 3.8 4 0 0 4 4 4 2 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 RUS88726.1 - 3.3e-33 114.3 0.1 3.3e-33 114.3 0.1 2.5 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 RUS88726.1 - 6.7e-29 100.0 1.2 2.6e-28 98.1 0.7 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 RUS88726.1 - 4.4e-22 78.5 7.8 1.8e-11 44.5 1.0 3.1 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain Formyl_trans_N PF00551.19 RUS88726.1 - 1e-12 48.1 0.1 2.1e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase CPSase_L_D2 PF02786.17 RUS88726.1 - 1.1e-05 25.0 0.1 0.00087 18.8 0.1 3.4 4 0 0 4 4 4 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 RUS88726.1 - 2.8e-05 24.2 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 RUS88726.1 - 7.4e-05 22.4 0.3 0.00042 19.9 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 RUS88726.1 - 0.00085 19.0 0.1 0.0076 15.9 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 RUS88726.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 RUS88726.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF2059 PF09832.9 RUS88726.1 - 0.19 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) tRNA_synt_1c_R1 PF04558.15 RUS88726.1 - 0.6 10.1 1.9 4 7.4 0.2 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 LAL_C2 PF18603.1 RUS88726.1 - 5.7 7.2 7.7 0.45 10.7 0.4 3.0 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 C5-epim_C PF06662.13 RUS88727.1 - 3.3e-59 199.5 0.1 5.6e-59 198.8 0.1 1.4 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus C5-epim_C PF06662.13 RUS88728.1 - 3.9e-58 196.1 0.0 5.8e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Ephrin_rec_like PF07699.13 RUS88728.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like V-set PF07686.17 RUS88730.1 - 0.00038 20.6 11.7 0.26 11.5 0.0 4.4 3 1 1 4 4 3 2 Immunoglobulin V-set domain TFIIA PF03153.13 RUS88730.1 - 0.0059 16.7 37.7 0.0099 15.9 37.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 RUS88730.1 - 0.011 14.2 0.9 0.015 13.7 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_23 PF13476.6 RUS88730.1 - 0.06 13.8 15.9 0.12 12.9 15.9 1.5 1 0 0 1 1 1 0 AAA domain Serinc PF03348.15 RUS88730.1 - 0.087 11.7 3.5 0.15 11.0 3.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ig_3 PF13927.6 RUS88730.1 - 0.13 12.8 2.8 0.9 10.2 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin domain Ig_6 PF18452.1 RUS88730.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF4834 PF16118.5 RUS88730.1 - 0.27 12.2 19.6 0.05 14.6 14.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FAM91_C PF14648.6 RUS88730.1 - 0.31 9.8 5.3 0.47 9.2 5.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus YjbH PF06082.11 RUS88730.1 - 0.36 9.6 11.6 0.53 9.0 11.6 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Ureide_permease PF07168.11 RUS88730.1 - 0.49 9.1 2.5 0.75 8.5 2.5 1.2 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 RUS88730.1 - 0.52 10.0 11.2 1 9.1 11.2 1.4 1 0 0 1 1 1 0 Connexin DUF2464 PF10240.9 RUS88730.1 - 0.72 9.4 9.0 1.4 8.4 9.0 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 GBP_C PF02841.14 RUS88730.1 - 0.73 9.2 26.1 1.2 8.5 26.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PIG-S PF10510.9 RUS88730.1 - 0.86 8.4 13.5 1.1 8.0 13.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Exonuc_VII_L PF02601.15 RUS88730.1 - 1.1 8.7 16.1 1.7 8.2 16.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3306 PF11748.8 RUS88730.1 - 1.1 10.1 18.5 0.096 13.6 10.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CLN3 PF02487.17 RUS88730.1 - 1.4 7.9 11.4 2.4 7.1 11.4 1.3 1 0 0 1 1 1 0 CLN3 protein MDM10 PF12519.8 RUS88730.1 - 1.4 7.7 14.4 2.1 7.1 14.4 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GAGA_bind PF06217.12 RUS88730.1 - 1.7 8.9 15.5 3.4 7.9 15.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.12 RUS88730.1 - 1.8 7.4 27.5 0.031 13.3 20.6 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIN_12 PF16289.5 RUS88730.1 - 1.9 9.0 5.7 3.6 8.1 5.7 1.4 1 0 0 1 1 1 0 PIN domain Spem1 PF15670.5 RUS88730.1 - 1.9 8.0 18.3 4.7 6.7 18.3 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 VPDSG-CTERM PF18205.1 RUS88730.1 - 2 8.3 7.6 22 5.0 0.0 2.5 1 1 1 2 2 2 0 VPDSG-CTERM motif DUF2828 PF11443.8 RUS88730.1 - 2.1 6.3 20.6 3.4 5.6 20.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Membralin PF09746.9 RUS88730.1 - 2.2 7.2 9.5 3.3 6.7 9.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein NARP1 PF12569.8 RUS88730.1 - 2.3 7.1 16.8 3.5 6.4 16.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EOS1 PF12326.8 RUS88730.1 - 3 7.8 8.3 7 6.5 8.3 1.6 1 0 0 1 1 1 0 N-glycosylation protein Pannexin_like PF12534.8 RUS88730.1 - 3 6.8 10.6 5 6.1 10.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 UvrD_C PF13361.6 RUS88730.1 - 3.3 7.0 14.3 21 4.4 13.5 2.0 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Otopetrin PF03189.13 RUS88730.1 - 3.3 6.4 6.6 4.4 6.0 6.6 1.2 1 0 0 1 1 1 0 Otopetrin CPSF100_C PF13299.6 RUS88730.1 - 3.5 7.8 19.4 0.22 11.7 11.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF853 PF05872.12 RUS88730.1 - 3.9 6.0 12.2 6.3 5.3 12.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Maf1 PF09174.10 RUS88730.1 - 4.2 7.5 10.4 16 5.6 8.9 2.1 2 0 0 2 2 2 0 Maf1 regulator G0-G1_switch_2 PF15103.6 RUS88730.1 - 5.1 7.6 11.3 18 5.8 11.3 2.0 1 0 0 1 1 1 0 G0/G1 switch protein 2 FemAB PF02388.16 RUS88730.1 - 5.6 5.7 17.2 8.9 5.1 17.2 1.2 1 0 0 1 1 1 0 FemAB family OATP PF03137.20 RUS88730.1 - 6.3 5.0 8.1 9.3 4.4 8.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.9 RUS88730.1 - 7 4.8 32.5 9.6 4.3 32.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIP5K PF01504.18 RUS88730.1 - 7.8 5.6 14.9 15 4.7 14.9 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ZYG-11_interact PF05884.12 RUS88730.1 - 8.5 5.7 6.3 15 4.9 6.3 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 SspB PF04386.13 RUS88730.1 - 8.6 6.2 20.7 0.19 11.6 12.4 2.1 2 0 0 2 2 2 0 Stringent starvation protein B LMBR1 PF04791.16 RUS88730.1 - 9.7 5.0 6.6 13 4.5 6.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 RUS88730.1 - 9.9 4.5 20.9 14 4.0 20.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TrbI PF03743.14 RUS88731.1 - 6.2 6.6 12.8 15 5.4 0.1 4.4 1 1 2 3 3 3 0 Bacterial conjugation TrbI-like protein FYRN PF05964.14 RUS88732.1 - 0.0011 18.8 62.0 12 5.8 0.1 13.8 14 0 0 14 14 14 9 F/Y-rich N-terminus VQ PF05678.14 RUS88733.1 - 3e-12 45.8 0.0 14 5.2 0.0 7.1 7 0 0 7 7 7 6 VQ motif Fibrinogen_aC PF12160.8 RUS88733.1 - 9.4e-05 22.2 6.5 2.3 8.1 1.2 3.8 1 1 4 5 5 5 5 Fibrinogen alpha C domain DUF2483 PF10656.9 RUS88733.1 - 0.00017 21.7 2.5 1.9 8.8 0.1 3.1 1 1 3 4 4 4 4 Hypothetical protein of unknown function (DUF2483) zf-H2C2 PF09337.10 RUS88733.1 - 0.0014 18.8 5.5 23 5.3 0.1 4.5 1 1 5 6 6 6 0 H2C2 zinc finger Phage_TAC_5 PF08890.11 RUS88733.1 - 0.0036 17.3 0.0 12 5.9 0.0 2.8 1 1 3 4 4 4 2 Phage XkdN-like tail assembly chaperone protein, TAC TetR_C_35 PF18556.1 RUS88733.1 - 0.0036 17.4 1.6 1.2 9.3 0.5 2.6 1 1 1 2 2 2 2 Bacterial Tetracyclin repressor, C-terminal domain DnaB PF00772.21 RUS88733.1 - 0.03 14.4 0.1 8.5 6.5 0.0 2.4 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain Spatacsin_C PF14649.6 RUS88733.1 - 0.03 13.4 0.1 6.4 5.8 0.0 2.5 1 1 2 3 3 3 0 Spatacsin C-terminus ORF45 PF17620.2 RUS88733.1 - 0.04 14.0 0.1 9.3 6.3 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function NIBRIN_BRCT_II PF16508.5 RUS88733.1 - 0.069 13.5 2.2 2.8 8.3 0.6 2.1 1 1 1 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF4846 PF16138.5 RUS88734.1 - 0.0081 15.7 0.1 11 5.4 0.0 3.1 1 1 4 5 5 5 3 Domain of unknown function (4846) CDC24 PF06395.11 RUS88734.1 - 0.017 15.3 1.7 7.7 6.8 0.3 3.3 1 1 2 3 3 3 0 CDC24 Calponin Keratin_B2 PF01500.17 RUS88734.1 - 0.068 13.2 9.9 59 3.6 9.9 3.3 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Cys_Knot_tox PF17486.2 RUS88734.1 - 0.12 12.6 3.7 39 4.6 0.1 3.3 1 1 3 4 4 4 0 Cystine knot toxins DeoRC PF00455.22 RUS88734.1 - 0.16 11.9 12.3 32 4.4 1.3 4.8 1 1 5 6 6 6 0 DeoR C terminal sensor domain TIR_3 PF18567.1 RUS88734.1 - 0.27 11.3 2.9 74 3.3 0.1 3.2 1 1 2 4 4 4 0 Toll/interleukin-1 receptor domain Adap_comp_sub PF00928.21 RUS88735.1 - 0.00018 21.0 1.6 0.0028 17.1 1.6 2.2 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DUF5045 PF16464.5 RUS88735.1 - 0.029 14.7 4.3 4.2 7.7 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5045) Herpes_BBRF1 PF04793.12 RUS88735.1 - 1.6 7.7 8.3 3.6 6.5 1.9 2.0 1 1 1 2 2 2 0 BRRF1-like protein YlzJ PF14035.6 RUS88736.1 - 1.4e-09 38.0 36.6 16 5.8 0.1 13.3 3 3 9 12 12 12 0 YlzJ-like protein TrmO_C PF18389.1 RUS88736.1 - 0.00021 21.4 24.4 38 4.5 0.3 10.9 2 2 9 11 11 11 0 TrmO C-terminal domain EutH PF04346.12 RUS88736.1 - 0.0012 18.1 7.4 19 4.3 0.1 5.5 1 1 4 6 6 6 0 Ethanolamine utilisation protein, EutH Band_7_1 PF13421.6 RUS88736.1 - 0.0012 18.6 0.2 20 4.8 0.0 4.2 1 1 4 5 5 5 0 SPFH domain-Band 7 family PPTA PF01239.22 RUS88736.1 - 0.0018 17.9 10.6 15 5.5 0.0 10.4 14 2 2 16 16 16 1 Protein prenyltransferase alpha subunit repeat Plug PF07715.15 RUS88736.1 - 0.01 16.4 6.2 4.6 7.9 0.4 3.9 1 1 2 3 3 3 0 TonB-dependent Receptor Plug Domain DUF3794 PF12673.7 RUS88736.1 - 0.02 15.1 14.7 40 4.6 0.2 6.2 2 2 7 9 9 9 0 Domain of unknown function (DUF3794) Importin_rep_3 PF18806.1 RUS88736.1 - 0.032 14.3 5.1 60 3.8 0.0 4.9 2 2 3 6 6 6 0 Importin 13 repeat GLYCAM-1 PF05242.11 RUS88736.1 - 1.9 8.6 20.2 2.6 8.2 1.9 4.0 1 1 4 5 5 5 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) YmgB PF10798.8 RUS88736.1 - 2.1 8.2 17.9 10 6.0 0.2 6.0 4 2 1 5 5 5 0 Biofilm development protein YmgB/AriR FAM104 PF15434.6 RUS88736.1 - 2.4 8.8 7.0 4.2 8.0 0.9 3.3 1 1 1 2 2 2 0 Family 104 FGE-sulfatase PF03781.16 RUS88737.1 - 2.7e-65 220.5 17.0 4.6e-52 177.2 11.6 2.2 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 fn3 PF00041.21 RUS88738.1 - 8.7e-60 199.1 11.6 2.1e-11 44.0 0.2 15.2 15 0 0 15 15 15 8 Fibronectin type III domain CHB_HEX_C_1 PF13290.6 RUS88738.1 - 1.4e-08 34.6 0.0 4.2e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 RUS88738.1 - 1.8e-07 31.2 0.0 5.7e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Fn3 associated Cupredoxin_1 PF13473.6 RUS88738.1 - 2.1e-07 31.0 0.0 3.7 7.7 0.0 6.7 7 0 0 7 7 7 1 Cupredoxin-like domain Pur_ac_phosph_N PF16656.5 RUS88738.1 - 5e-06 27.0 4.4 0.2 12.3 0.1 6.9 7 0 0 7 7 7 1 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 RUS88738.1 - 0.0043 16.9 0.0 24 4.9 0.0 5.3 5 0 0 5 5 5 0 Fibronectin-III type domain ObR_Ig PF18589.1 RUS88738.1 - 0.042 14.2 0.0 0.96 9.9 0.1 3.1 3 0 0 3 3 3 0 Obesity receptor immunoglobulin like domain Interfer-bind PF09294.10 RUS88738.1 - 0.065 13.6 0.9 6.5 7.1 0.0 4.2 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III Thioredoxin_2 PF13098.6 RUS88738.1 - 0.15 12.5 0.0 0.52 10.8 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain CCDC53 PF10152.9 RUS88739.1 - 5.2e-05 23.7 0.1 7.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Baculo_PEP_C PF04513.12 RUS88739.1 - 0.049 13.7 0.0 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-H2C2_2 PF13465.6 RUS88740.1 - 3.3e-38 128.4 99.1 9.3e-09 35.3 0.2 14.7 15 0 0 15 15 15 9 Zinc-finger double domain zf-C2H2 PF00096.26 RUS88740.1 - 1.2e-26 91.6 107.4 5.5e-05 23.4 4.6 14.0 14 1 0 14 14 13 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS88740.1 - 7.3e-26 88.6 103.2 0.00053 20.6 0.3 14.0 15 0 0 15 15 13 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS88740.1 - 1.1e-05 25.1 0.7 1.1e-05 25.1 0.7 9.4 11 0 0 11 11 10 2 C2H2-type zinc-finger domain zf-met PF12874.7 RUS88740.1 - 2.7e-05 24.4 63.7 0.045 14.2 0.6 12.5 13 0 0 13 13 12 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS88740.1 - 0.0073 16.3 0.2 0.0073 16.3 0.2 12.9 12 1 0 12 12 12 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS88740.1 - 0.1 12.9 0.1 0.1 12.9 0.1 12.6 13 0 0 13 13 13 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RUS88740.1 - 0.35 11.2 62.1 0.35 11.2 2.0 9.4 3 3 4 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS88740.1 - 0.53 11.0 41.8 1.3 9.7 7.4 7.3 1 1 5 7 7 7 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 RUS88740.1 - 2.7 8.3 11.5 32 4.9 0.5 5.0 3 1 3 6 6 6 0 BolA-like protein Zn-ribbon_8 PF09723.10 RUS88740.1 - 3.3 7.9 47.5 2.4 8.3 2.7 9.8 8 3 3 11 11 11 0 Zinc ribbon domain zf_UBZ PF18439.1 RUS88740.1 - 5.7 6.6 37.4 9.4 5.9 0.1 9.8 11 0 0 11 11 11 0 Ubiquitin-Binding Zinc Finger Cys_rich_CPXG PF14255.6 RUS88740.1 - 7.9 6.5 12.2 56 3.7 0.0 5.8 6 0 0 6 6 6 0 Cysteine-rich CPXCG GST_C_3 PF14497.6 RUS88741.1 - 1.1e-12 48.0 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RUS88741.1 - 2.2e-09 37.5 0.0 5.1e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RUS88741.1 - 1.3e-05 25.5 0.0 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 RUS88741.1 - 7.5e-05 23.4 0.0 0.00049 20.8 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 RUS88741.1 - 8.1e-05 22.8 0.1 0.00028 21.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RUS88741.1 - 0.0043 17.3 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BTB PF00651.31 RUS88743.1 - 2.7e-27 95.2 0.3 2.1e-25 89.1 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 RUS88743.1 - 5.9e-22 77.7 0.1 3.9e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 RUS88745.1 - 2.5e-60 199.8 13.7 3e-15 55.5 0.0 5.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 RUS88745.1 - 1.6e-33 113.9 5.5 1.8e-07 31.2 0.0 5.5 2 1 4 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RUS88745.1 - 2.1e-29 101.2 2.0 5.9e-06 26.4 0.1 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS88745.1 - 1.1e-26 91.7 0.9 2.7e-05 23.9 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 RUS88745.1 - 3.3e-24 84.6 1.6 1.2e-06 28.4 0.1 5.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS88745.1 - 9e-12 44.7 15.4 0.016 15.2 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF5122 PF17164.4 RUS88745.1 - 0.25 11.7 2.6 3.6 8.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller EGF_2 PF07974.13 RUS88747.1 - 0.0019 18.5 33.9 0.0063 16.9 11.1 5.6 5 1 0 5 5 5 3 EGF-like domain I-EGF_1 PF18372.1 RUS88747.1 - 0.0022 18.0 7.5 0.0022 18.0 7.5 5.6 7 0 0 7 7 7 3 Integrin beta epidermal growth factor like domain 1 OTU PF02338.19 RUS88749.1 - 3.7e-15 56.5 0.8 8.7e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RUS88749.1 - 0.00077 19.0 0.1 0.075 12.5 0.1 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain DnaA_N PF11638.8 RUS88749.1 - 0.069 12.9 1.0 6 6.7 0.0 2.5 2 0 0 2 2 2 0 DnaA N-terminal domain DUF4090 PF13319.6 RUS88749.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) COG5 PF10392.9 RUS88750.1 - 3.7e-29 101.6 1.1 3.7e-29 101.6 1.1 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 RUS88750.1 - 1.7e-05 24.8 1.0 0.00072 19.6 0.2 3.4 2 1 1 3 3 3 1 Vps51/Vps67 CLZ PF16526.5 RUS88750.1 - 0.026 14.9 2.1 0.086 13.2 0.0 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CelTOS PF18659.1 RUS88750.1 - 0.15 12.5 0.6 1.9 8.9 0.1 2.8 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Vps54_N PF10475.9 RUS88750.1 - 0.16 11.2 3.5 0.38 10.0 3.5 1.6 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 RUS88750.1 - 0.8 9.8 6.0 0.73 9.9 0.4 3.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 RUS88750.1 - 0.95 8.4 5.9 28 3.5 0.0 4.0 3 1 1 4 4 4 0 Vps53-like, N-terminal RRM_1 PF00076.22 RUS88751.1 - 1.9e-05 24.4 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS88751.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif IRK_N PF08466.10 RUS88751.1 - 0.12 12.5 0.1 0.38 11.0 0.1 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal WAP PF00095.21 RUS88752.1 - 1.4e-06 28.6 9.5 1.4e-06 28.6 9.5 3.4 3 2 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Neur_chan_memb PF02932.16 RUS88753.1 - 2.5e-31 109.6 0.0 3.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS88753.1 - 1.2e-22 80.5 0.3 1.2e-22 80.5 0.3 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1387 PF07139.11 RUS88753.1 - 0.15 11.8 5.6 0.21 11.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Spt20 PF12090.8 RUS88753.1 - 0.28 10.8 12.6 0.43 10.2 12.6 1.3 1 0 0 1 1 1 0 Spt20 family Importin_rep_6 PF18829.1 RUS88754.1 - 0.00034 20.7 2.0 3.3 7.9 0.1 4.0 1 1 3 4 4 4 1 Importin repeat 6 DUF2576 PF10845.8 RUS88754.1 - 0.00045 19.8 1.7 56 3.5 0.0 5.3 3 1 1 6 6 6 0 Protein of unknown function (DUF2576) GerD PF17898.1 RUS88754.1 - 0.0039 17.1 0.1 4.3 7.3 0.0 3.0 1 1 3 4 4 4 3 Spore germination GerD central core domain Pkip-1 PF06878.11 RUS88754.1 - 0.0078 16.3 0.4 7.8 6.6 0.0 2.9 1 1 2 3 3 3 1 Pkip-1 protein zf-TFIIIC PF12660.7 RUS88754.1 - 0.037 14.0 0.6 3.4 7.7 0.0 2.8 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Ribosomal_L36 PF00444.18 RUS88754.1 - 0.16 12.2 1.2 10 6.5 0.0 3.6 4 1 1 5 5 5 0 Ribosomal protein L36 SipA PF09052.10 RUS88754.1 - 0.18 11.4 0.9 3.5 7.2 0.2 2.3 1 1 2 3 3 3 0 SipA N-terminal domain DUF4866 PF16160.5 RUS88754.1 - 0.41 9.9 5.5 18 4.6 0.1 3.5 1 1 2 4 4 4 0 Domain of unknown function (DUF4866) Galactosyl_T PF01762.21 RUS88755.1 - 1.2e-14 54.6 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Grp7_allergen PF16984.5 RUS88756.1 - 0.14 12.2 3.6 13 5.8 0.3 3.2 1 1 2 3 3 3 0 Group 7 allergen HEAT PF02985.22 RUS88757.1 - 3e-13 48.8 4.4 0.0073 16.5 0.0 8.1 9 0 0 9 9 7 3 HEAT repeat HEAT_2 PF13646.6 RUS88757.1 - 1e-12 48.2 5.8 0.034 14.5 0.2 7.5 6 3 1 7 7 7 3 HEAT repeats IBN_N PF03810.19 RUS88757.1 - 2.1e-12 46.8 2.3 7e-10 38.7 0.7 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 RUS88757.1 - 2.1e-12 47.3 6.4 0.065 13.8 0.0 9.5 8 2 2 10 10 10 4 HEAT-like repeat Cnd1 PF12717.7 RUS88757.1 - 3.2e-08 33.8 13.3 0.027 14.5 0.0 5.3 5 2 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 RUS88757.1 - 3.4e-07 30.1 2.0 1.1 9.2 0.2 6.4 5 2 0 5 5 5 2 UME (NUC010) domain DRIM PF07539.12 RUS88757.1 - 0.00016 20.2 7.2 0.34 9.2 0.1 5.1 2 1 2 5 5 5 2 Down-regulated in metastasis BP28CT PF08146.12 RUS88757.1 - 0.00016 21.6 0.3 0.18 11.7 0.0 4.3 4 0 0 4 4 4 1 BP28CT (NUC211) domain RIX1 PF08167.12 RUS88757.1 - 0.00025 20.9 0.1 0.77 9.5 0.0 4.9 4 1 0 5 5 5 1 rRNA processing/ribosome biogenesis FANCI_S3 PF14677.6 RUS88757.1 - 0.0045 16.7 0.9 0.73 9.5 0.0 4.1 2 2 2 4 4 4 1 FANCI solenoid 3 Tti2 PF10521.9 RUS88757.1 - 0.018 14.6 0.1 1.5 8.3 0.0 3.6 3 1 1 4 4 4 0 Tti2 family Importin_rep_4 PF18808.1 RUS88757.1 - 5.6 7.3 10.3 1.1 9.5 0.1 4.4 5 0 0 5 5 5 0 Importin repeat CAP PF00188.26 RUS88758.1 - 1.9e-27 96.6 2.3 2.9e-27 96.0 2.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1943 PF09172.11 RUS88759.1 - 0.063 12.5 0.2 0.07 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF1062 PF06353.12 RUS88759.1 - 0.64 10.8 3.8 3.4 8.5 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1062) RPN2_C PF18004.1 RUS88760.1 - 1e-48 165.3 12.5 1e-48 165.3 12.5 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 RUS88760.1 - 2.2e-40 135.1 20.8 3.4e-08 33.5 0.1 8.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RUS88760.1 - 1.2e-16 60.9 0.1 4.4e-13 49.4 0.0 4.2 2 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 RUS88760.1 - 0.00017 21.5 0.6 2.8 8.4 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 RUS88760.1 - 0.0012 18.9 0.1 0.77 9.8 0.0 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS88760.1 - 0.0013 19.1 1.1 0.0095 16.4 0.0 3.1 4 0 0 4 4 4 1 HEAT-like repeat RT_RNaseH_2 PF17919.1 RUS88762.1 - 7.6e-37 125.4 0.0 8e-36 122.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS88762.1 - 1e-36 125.4 0.0 6.9e-36 122.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS88762.1 - 6.3e-18 65.1 0.0 2.2e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS88762.1 - 4e-07 30.0 1.2 0.0001 22.3 1.2 2.9 1 1 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RUS88762.1 - 8.4e-05 22.3 0.0 0.00025 20.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Orn_Arg_deC_N PF02784.16 RUS88763.1 - 1.9e-78 263.3 0.0 2.4e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RUS88763.1 - 5.8e-19 68.2 0.0 1e-17 64.1 0.0 2.2 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF5448 PF17526.2 RUS88763.1 - 0.029 14.5 0.4 0.067 13.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5448) TRAPP PF04051.16 RUS88765.1 - 6.2e-38 129.8 0.1 7.2e-38 129.6 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Sulfotransfer_1 PF00685.27 RUS88766.1 - 2.5e-28 99.3 0.0 3.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS88766.1 - 1.3e-07 32.3 0.2 0.0053 17.2 0.2 3.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS88766.1 - 0.00094 19.2 0.4 0.0014 18.6 0.4 1.3 1 0 0 1 1 1 1 Sulfotransferase family ELYS-bb PF16687.5 RUS88766.1 - 0.085 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Sulfotransfer_1 PF00685.27 RUS88767.1 - 7.8e-23 81.3 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS88767.1 - 6.4e-14 52.8 0.0 2.9e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family TRM13 PF05206.14 RUS88768.1 - 8.2e-77 258.3 1.2 2.6e-38 132.1 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 RUS88768.1 - 3.6e-08 33.0 3.7 3.6e-08 33.0 3.7 2.5 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 RUS88768.1 - 7e-07 29.0 5.6 1.6e-06 27.9 5.6 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RUS88768.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.8 3 1 1 4 4 4 0 Methyltransferase domain UBA PF00627.31 RUS88769.1 - 3.3e-29 100.3 4.1 6e-15 54.8 0.9 2.4 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 RUS88769.1 - 1.9e-24 85.2 16.1 3.6e-24 84.3 16.1 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 RUS88769.1 - 6.1e-22 77.2 1.2 1.1e-21 76.4 1.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS88769.1 - 1.1e-08 34.8 1.7 1.7e-08 34.1 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 RUS88769.1 - 0.00043 20.4 0.1 0.00076 19.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RUS88769.1 - 0.0026 18.3 0.0 0.0054 17.3 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 RUS88769.1 - 0.0026 17.5 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 RUS88769.1 - 0.044 14.1 0.4 0.086 13.2 0.4 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 RUS88769.1 - 0.074 12.8 0.2 0.35 10.6 0.2 2.2 2 1 0 2 2 2 0 CUE domain Ubiquitin_4 PF18036.1 RUS88769.1 - 0.29 11.2 1.0 1.3 9.1 0.3 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain STI1 PF17830.1 RUS88769.1 - 0.74 9.8 8.8 0.073 13.0 2.6 2.5 2 1 1 3 3 3 0 STI1 domain Totivirus_coat PF05518.11 RUS88769.1 - 4.8 5.1 15.0 3.4 5.6 0.3 2.1 2 0 0 2 2 2 0 Totivirus coat protein Plasmodium_HRP PF05403.11 RUS88770.1 - 0.00063 19.6 35.6 0.067 13.0 13.6 2.1 2 0 0 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) ELO PF01151.18 RUS88772.1 - 1.8e-62 211.1 23.9 2.2e-62 210.8 23.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GRIM-19 PF06212.12 RUS88772.1 - 0.023 14.7 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 GRIM-19 protein DUF2663 PF10864.8 RUS88772.1 - 3.1 8.2 8.2 0.81 10.1 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) TPT PF03151.16 RUS88773.1 - 3e-05 23.5 5.3 3.5e-05 23.3 5.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2070 PF09843.9 RUS88773.1 - 2.2 6.5 9.1 2.4 6.3 9.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RNase_H PF00075.24 RUS88774.1 - 1.4e-06 28.6 0.0 1.4e-06 28.6 0.0 2.6 3 0 0 3 3 3 1 RNase H Coilin_N PF15862.5 RUS88774.1 - 0.0027 17.5 21.8 0.0027 17.5 21.8 1.7 2 0 0 2 2 2 1 Coilin N-terminus GAGA_bind PF06217.12 RUS88774.1 - 0.02 15.2 21.1 0.028 14.7 21.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF853 PF05872.12 RUS88774.1 - 0.39 9.3 5.5 0.41 9.2 5.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PcfK PF14058.6 RUS88774.1 - 0.63 10.3 27.9 0.038 14.3 22.4 1.8 2 0 0 2 2 2 0 PcfK-like protein Rxt3 PF08642.10 RUS88774.1 - 1.4 9.7 11.8 1.5 9.6 7.6 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 U79_P34 PF03064.16 RUS88774.1 - 1.5 8.2 23.2 2.4 7.4 23.2 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DAG_kinase_N PF14513.6 RUS88774.1 - 2.2 8.5 15.4 1 9.5 12.2 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RPN2_C PF18004.1 RUS88774.1 - 3.7 7.4 30.3 0.48 10.3 25.9 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_Rpc4 PF05132.14 RUS88774.1 - 4 7.9 19.8 0.25 11.8 14.8 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF3807 PF12720.7 RUS88774.1 - 5 7.4 28.4 1.3 9.3 23.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CPSF100_C PF13299.6 RUS88774.1 - 5 7.3 19.4 7.4 6.7 15.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 RUS88774.1 - 5.7 7.2 34.7 1 9.6 29.1 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.8 RUS88774.1 - 6.5 5.4 21.2 4.1 6.1 18.9 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Serinc PF03348.15 RUS88774.1 - 6.6 5.5 5.5 8.9 5.1 5.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RICTOR_N PF14664.6 RUS88775.1 - 7.7e-87 291.7 0.1 3.8e-86 289.4 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 RUS88775.1 - 6.3e-34 116.6 4.8 1.6e-33 115.4 0.5 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 RUS88775.1 - 5.9e-25 87.3 2.5 6.8e-23 80.7 0.7 3.2 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 RUS88775.1 - 2.7e-23 81.7 0.2 2.7e-23 81.7 0.2 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain HEAT_EZ PF13513.6 RUS88775.1 - 0.021 15.3 0.0 3.1 8.4 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Cadherin PF00028.17 RUS88776.1 - 4e-27 94.5 0.0 5.4e-10 39.6 0.0 3.7 3 1 1 4 4 4 3 Cadherin domain Cadherin_pro PF08758.11 RUS88776.1 - 0.00032 20.8 0.0 0.037 14.2 0.0 2.8 2 1 1 3 3 3 1 Cadherin prodomain like DUF1102 PF06510.11 RUS88776.1 - 0.014 15.6 0.1 0.047 13.9 0.1 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1102) MVL PF12151.8 RUS88776.1 - 0.12 12.3 1.7 0.25 11.2 1.7 1.5 1 0 0 1 1 1 0 Mannan-binding protein Cadherin_2 PF08266.12 RUS88776.1 - 0.17 11.7 0.0 0.84 9.5 0.0 2.1 3 0 0 3 3 3 0 Cadherin-like DUF4213 PF13938.6 RUS88776.1 - 0.26 11.5 1.0 16 5.8 0.1 2.3 1 1 1 2 2 2 0 Putative heavy-metal chelation Cadherin PF00028.17 RUS88778.1 - 1.1e-227 737.3 33.8 9.5e-21 74.0 0.1 16.4 15 2 1 16 16 16 16 Cadherin domain Cadherin_3 PF16184.5 RUS88778.1 - 7.4e-19 67.8 18.7 0.0059 16.6 0.1 11.0 12 0 0 12 12 12 5 Cadherin-like Cadherin_2 PF08266.12 RUS88778.1 - 2.1e-15 56.3 0.0 0.15 11.9 0.0 10.9 11 1 0 11 11 11 3 Cadherin-like Cadherin_pro PF08758.11 RUS88778.1 - 2.6e-09 37.1 2.9 0.79 9.9 0.0 6.7 7 0 0 7 7 7 4 Cadherin prodomain like RET_CLD1 PF17756.1 RUS88778.1 - 3.2e-08 33.9 0.0 23 5.3 0.0 8.1 9 0 0 9 9 9 0 RET Cadherin like domain 1 PQQ PF01011.21 RUS88778.1 - 0.037 13.9 0.1 0.67 10.0 0.1 3.4 1 0 0 1 1 1 0 PQQ enzyme repeat Y_Y_Y PF07495.13 RUS88778.1 - 0.067 13.1 5.1 91 3.1 0.0 6.5 8 0 0 8 8 8 0 Y_Y_Y domain SusE PF14292.6 RUS88778.1 - 3.8 7.8 11.0 1.5 9.1 0.2 5.5 5 0 0 5 5 5 0 SusE outer membrane protein Ank_5 PF13857.6 RUS88784.1 - 1.7e-14 53.6 10.0 1.3e-07 31.7 2.5 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS88784.1 - 2.5e-10 40.3 10.8 0.0018 18.7 1.8 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 RUS88784.1 - 4.5e-10 39.9 5.9 0.004 17.7 0.2 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88784.1 - 5.1e-10 38.7 3.6 0.0024 18.2 0.3 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RUS88784.1 - 5.2e-07 30.2 10.2 6.7e-06 26.6 9.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 RUS88784.1 - 3.3e-06 27.5 0.0 9.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 PH domain HSNSD PF12062.8 RUS88784.1 - 1.8 7.2 7.8 0.16 10.6 0.1 2.1 2 0 0 2 2 2 0 heparan sulfate-N-deacetylase MID_MedPIWI PF18296.1 RUS88784.1 - 3 7.5 12.2 1 9.1 6.8 2.3 2 0 0 2 2 2 0 MID domain of medPIWI Mpp10 PF04006.12 RUS88784.1 - 3.5 5.9 52.2 9 4.6 52.2 1.6 1 0 0 1 1 1 0 Mpp10 protein Trypsin_2 PF13365.6 RUS88786.1 - 1.7e-05 25.7 0.0 3.9e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Bact_transglu_N PF08379.10 RUS88786.1 - 0.027 15.4 0.2 15 6.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial transglutaminase-like N-terminal region DUF2389 PF09493.10 RUS88786.1 - 0.041 14.5 0.3 17 6.1 0.0 2.6 2 0 0 2 2 2 0 Tryptophan-rich protein (DUF2389) Elicitin PF00964.17 RUS88786.1 - 0.041 14.0 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Elicitin HigB-like_toxin PF05015.13 RUS88786.1 - 0.077 13.4 3.0 15 6.1 0.1 3.1 2 1 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB Whi5 PF08528.11 RUS88786.1 - 0.25 11.0 1.7 18 5.0 0.1 2.5 2 0 0 2 2 2 0 Whi5 like 7tm_1 PF00001.21 RUS88787.1 - 2.2e-10 40.3 16.6 3.1e-10 39.8 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS88787.1 - 0.0073 16.0 18.6 0.018 14.7 17.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Trp_oprn_chp PF09534.10 RUS88787.1 - 0.27 11.0 2.3 0.53 10.1 0.1 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SecD_SecF PF02355.16 RUS88787.1 - 4.9 6.5 14.7 0.36 10.2 1.3 3.5 4 0 0 4 4 4 0 Protein export membrane protein ParA PF10609.9 RUS88788.1 - 7.2e-95 317.1 0.0 8.4e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RUS88788.1 - 7.3e-10 39.0 0.0 2.8e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 RUS88788.1 - 4.2e-06 26.2 0.1 0.0003 20.1 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 RUS88788.1 - 4.7e-06 26.6 1.6 0.00066 19.6 0.0 2.7 3 1 0 3 3 3 1 AAA domain MipZ PF09140.11 RUS88788.1 - 1.7e-05 24.3 0.0 4.9e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 RUS88788.1 - 3.5e-05 23.4 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 RUS88788.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 RUS88788.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 RUS88788.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 RUS88788.1 - 0.0022 17.2 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain MeaB PF03308.16 RUS88788.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 RUS88788.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 RUS88788.1 - 0.014 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RUS88788.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UPF0179 PF03684.13 RUS88788.1 - 0.019 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) CBP_BcsQ PF06564.12 RUS88788.1 - 0.026 14.0 0.0 0.084 12.3 0.0 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_30 PF13604.6 RUS88788.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 RUS88788.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 RUS88788.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 RUS88788.1 - 0.07 12.8 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 RUS88788.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CLP1_P PF16575.5 RUS88788.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 RUS88788.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 RUS88788.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Kelch_1 PF01344.25 RUS88789.1 - 4.8e-70 230.9 18.5 3.5e-13 48.9 0.4 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RUS88789.1 - 3.3e-45 151.0 1.5 5.5e-09 36.0 0.0 6.4 2 1 4 6 6 6 6 Kelch motif BACK PF07707.15 RUS88789.1 - 1.3e-30 105.6 1.8 2.4e-30 104.7 0.5 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS88789.1 - 6.6e-30 103.6 0.1 2.1e-29 102.0 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 RUS88789.1 - 8.1e-29 98.5 1.6 4.1e-06 26.6 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 RUS88789.1 - 9.9e-25 86.3 2.8 4.2e-05 23.5 0.0 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS88789.1 - 2.5e-22 78.6 3.7 0.00025 21.2 0.2 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS88789.1 - 4.8e-12 45.6 1.4 0.014 15.4 0.0 6.4 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.6 RUS88789.1 - 0.0025 18.3 5.9 16 6.2 0.1 4.7 5 0 0 5 5 5 1 PQQ-like domain PGK PF00162.19 RUS88790.1 - 3.3e-27 95.4 0.0 1.8e-24 86.4 0.0 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase PGK PF00162.19 RUS88791.1 - 5.1e-130 433.8 0.0 2.3e-90 303.3 0.0 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase EBV-NA1 PF02905.14 RUS88791.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain PGK PF00162.19 RUS88792.1 - 6.8e-39 133.9 0.0 8.9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase THEG PF14912.6 RUS88792.1 - 1.2e-05 25.7 7.8 0.0017 18.8 1.1 3.2 2 1 1 3 3 3 3 Testicular haploid expressed repeat Fer4_14 PF13394.6 RUS88793.1 - 0.21 11.7 1.0 0.57 10.3 1.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain PARM PF17061.5 RUS88794.1 - 1 9.4 18.4 1.4 8.9 18.4 1.2 1 0 0 1 1 1 0 PARM SelP_N PF04592.14 RUS88795.1 - 4.5 6.6 20.6 0.035 13.5 10.6 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IATP PF04568.12 RUS88796.1 - 1.5e-25 89.5 3.0 2e-25 89.0 3.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.10 RUS88796.1 - 0.0015 18.7 3.1 0.002 18.4 3.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family NADH-UOR_E PF16514.5 RUS88796.1 - 0.074 13.4 0.9 0.1 12.9 0.9 1.3 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Guanylate_cyc PF00211.20 RUS88797.1 - 4.5e-64 215.5 0.0 7.1e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS88797.1 - 1.6e-40 139.0 0.0 2.4e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS88797.1 - 2.4e-30 105.8 0.0 3.8e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 RUS88797.1 - 1e-22 80.7 0.5 1.5e-22 80.2 0.5 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Cep57_MT_bd PF06657.13 RUS88797.1 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 HNOBA PF07701.14 RUS88797.1 - 0.0033 16.9 0.3 0.0054 16.2 0.3 1.3 1 0 0 1 1 1 1 Heme NO binding associated VPS11_C PF12451.8 RUS88797.1 - 0.004 17.4 0.1 0.0097 16.1 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal ANF_receptor PF01094.28 RUS88798.1 - 2.7e-16 59.6 0.1 3.4e-16 59.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region I-set PF07679.16 RUS88799.1 - 1.6e-26 92.2 0.0 1.2e-10 41.3 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS88799.1 - 5.3e-25 87.8 0.0 3.1e-12 46.9 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 RUS88799.1 - 8.4e-18 64.3 0.0 7.9e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS88799.1 - 2e-14 53.7 0.0 1.1e-08 35.3 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS88799.1 - 8.5e-13 48.4 0.1 0.00039 20.6 0.1 4.5 3 2 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS88799.1 - 6.5e-06 26.1 0.0 0.039 14.0 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS88799.1 - 0.00012 21.5 0.0 0.11 12.0 0.0 3.4 4 0 0 4 4 4 1 Immunoglobulin domain Ig_5 PF16681.5 RUS88799.1 - 0.00023 21.5 0.0 0.14 12.5 0.0 3.1 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 RUS88799.1 - 0.0037 17.3 0.0 0.054 13.6 0.0 2.4 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS88799.1 - 0.012 15.8 0.0 0.87 9.9 0.0 3.3 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain PKD_3 PF16820.5 RUS88799.1 - 0.092 12.5 0.0 13 5.6 0.0 2.6 3 0 0 3 3 3 0 PKD-like domain Cactin_mid PF10312.9 RUS88800.1 - 1.9e-65 220.3 3.2 1.9e-65 220.3 3.2 2.3 2 1 1 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 RUS88800.1 - 3.8e-57 191.6 11.1 6.8e-57 190.8 11.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AAA_17 PF13207.6 RUS88800.1 - 3.9 7.9 9.2 0.61 10.5 0.7 3.0 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 RUS88801.1 - 1.4e-19 70.5 0.5 7.7e-07 29.6 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS88801.1 - 1.8e-18 66.7 0.3 0.0033 18.0 0.0 5.6 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS88801.1 - 3.2e-17 60.8 3.7 0.069 13.7 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 RUS88801.1 - 1.2e-13 50.8 0.5 0.24 11.9 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 RUS88801.1 - 1.2e-10 41.4 0.2 0.0058 16.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Mnd1 PF03962.15 RUS88801.1 - 0.16 12.3 0.2 5.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Mnd1 HTH domain FWWh PF14922.6 RUS88802.1 - 3.1e-26 92.1 0.3 1.1e-24 87.1 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function Snapin_Pallidin PF14712.6 RUS88802.1 - 0.015 15.7 5.2 0.18 12.3 0.4 3.5 4 0 0 4 4 4 0 Snapin/Pallidin V_ATPase_I PF01496.19 RUS88802.1 - 0.097 10.6 0.9 0.19 9.6 0.1 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 RUS88802.1 - 0.19 11.9 2.2 0.58 10.3 0.7 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 RUS88802.1 - 0.84 10.2 5.5 5.3 7.7 0.7 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF4391 PF14335.6 RUS88802.1 - 1.1 8.9 5.3 0.5 10.0 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Spc24 PF08286.11 RUS88802.1 - 1.2 9.5 7.0 3.7 7.8 2.1 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 GalKase_gal_bdg PF10509.9 RUS88803.1 - 1.8e-25 88.2 0.0 3.7e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 RUS88803.1 - 1.3e-13 50.9 1.2 2.7e-13 49.9 1.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RUS88803.1 - 1.1e-11 44.9 0.1 2.7e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Ndufs5 PF10200.9 RUS88803.1 - 0.15 12.4 0.1 2.5 8.4 0.0 2.4 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF1356 PF07092.12 RUS88804.1 - 1.8e-34 119.0 0.1 2.4e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 RUS88804.1 - 0.00098 19.0 0.1 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein FERM_C PF09380.10 RUS88806.1 - 1.7e-20 73.2 0.0 3.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS88806.1 - 5.7e-20 71.9 1.0 5.7e-20 71.9 1.0 2.2 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.10 RUS88806.1 - 2.8e-16 59.2 0.1 5.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 RUS88806.1 - 1.8e-12 47.1 11.8 1.8e-12 47.1 11.8 3.4 3 0 0 3 3 3 1 FERM adjacent (FA) UPF0242 PF06785.11 RUS88807.1 - 8.8e-05 22.7 15.9 8.8e-05 22.7 15.9 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 RUS88807.1 - 0.0038 16.7 18.7 0.0038 16.7 18.7 2.2 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal HrpB7 PF09486.10 RUS88807.1 - 0.44 10.9 13.6 0.034 14.5 6.8 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 RUS88807.1 - 1.1 9.4 23.8 0.76 10.0 11.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family T3SS_basalb_I PF17001.5 RUS88807.1 - 4.3 8.0 8.5 1.8 9.2 0.6 3.3 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Spc7 PF08317.11 RUS88807.1 - 5.7 5.7 33.9 0.021 13.7 14.6 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF2605 PF10792.9 RUS88807.1 - 6.7 6.7 11.2 0.31 11.0 3.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) MscS_porin PF12795.7 RUS88807.1 - 6.9 6.1 23.4 48 3.4 0.4 3.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 RUS88807.1 - 8.6 5.8 20.9 0.77 9.3 8.9 2.4 1 1 0 2 2 2 0 Exonuclease VII, large subunit MA3 PF02847.17 RUS88808.1 - 2.1e-44 150.1 1.7 2.6e-24 85.4 0.1 2.6 3 0 0 3 3 3 2 MA3 domain DUF4942 PF13708.6 RUS88808.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) DUF1460 PF07313.12 RUS88808.1 - 0.2 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) LRR_5 PF13306.6 RUS88809.1 - 1.5e-09 37.9 4.7 1.1e-05 25.4 3.1 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 RUS88809.1 - 2.9e-07 30.2 0.0 0.0024 17.6 0.0 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RUS88809.1 - 0.0075 16.7 0.0 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Jas PF16135.5 RUS88811.1 - 0.015 15.4 2.6 0.45 10.7 0.0 2.6 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Toxin_13 PF07822.11 RUS88812.1 - 1.4 9.1 13.0 1.4 9.1 6.7 2.3 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein zf-SNAP50_C PF12251.8 RUS88814.1 - 3.5e-61 206.4 2.0 5.1e-61 205.8 2.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Pkinase_Tyr PF07714.17 RUS88815.1 - 3.1e-45 154.5 0.0 4.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 RUS88815.1 - 2e-42 143.6 0.0 5e-12 46.2 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 RUS88815.1 - 9.6e-41 137.8 0.0 2.6e-10 40.2 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS88815.1 - 8.5e-29 99.7 0.0 1.8e-08 34.6 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 RUS88815.1 - 8.8e-22 77.1 0.0 4.6e-07 29.9 0.0 5.4 5 1 0 5 5 5 4 Immunoglobulin domain Pkinase PF00069.25 RUS88815.1 - 1.1e-20 74.1 0.0 2.7e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain V-set PF07686.17 RUS88815.1 - 1.7e-12 47.5 1.1 0.41 10.8 0.0 6.8 5 2 2 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS88815.1 - 1.4e-06 27.7 0.0 2.4 7.8 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS88815.1 - 1.8e-05 24.7 0.2 1.7 8.7 0.0 5.0 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 RUS88815.1 - 2.3e-05 24.4 0.0 0.12 12.5 0.0 3.1 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain CD34_antigen PF06365.12 RUS88815.1 - 0.051 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family PD40 PF07676.12 RUS88815.1 - 0.13 12.2 1.9 22 5.2 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Antistasin PF02822.14 RUS88816.1 - 7.8e-16 58.4 100.4 2.5e-05 24.8 7.9 8.0 8 3 0 8 8 8 6 Antistasin family Sulfotransfer_2 PF03567.14 RUS88817.1 - 5.1e-26 92.1 0.7 3.9e-21 76.1 0.0 2.6 2 1 1 3 3 3 2 Sulfotransferase family Nop14 PF04147.12 RUS88817.1 - 6.9e-05 21.3 11.6 8.1e-05 21.1 11.6 1.1 1 0 0 1 1 1 1 Nop14-like family PI3K_1B_p101 PF10486.9 RUS88817.1 - 0.0036 15.2 1.2 0.0052 14.7 1.2 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 RUS88817.1 - 0.0041 17.3 14.3 0.0072 16.5 14.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 RUS88817.1 - 0.032 12.6 12.4 0.039 12.3 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RUS88817.1 - 0.48 8.5 36.4 0.67 8.0 36.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 RUS88817.1 - 0.81 7.9 9.1 1.1 7.4 9.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.9 RUS88817.1 - 1 8.4 34.4 1.7 7.7 34.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 RUS88817.1 - 1.2 8.5 21.1 1.8 7.9 21.1 1.3 1 0 0 1 1 1 0 SDA1 Glypican PF01153.19 RUS88817.1 - 1.2 7.8 7.4 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Glypican BUD22 PF09073.10 RUS88817.1 - 4.1 6.7 23.8 6.3 6.0 23.8 1.2 1 0 0 1 1 1 0 BUD22 GP46 PF07409.12 RUS88817.1 - 6.9 6.5 6.3 14 5.4 6.3 1.5 1 0 0 1 1 1 0 Phage protein GP46 Methyltransf_3 PF01596.17 RUS88818.1 - 1.2e-29 103.1 0.0 1.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 RUS88818.1 - 3.3e-09 37.7 0.0 7.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS88818.1 - 0.00081 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 RUS88818.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 RUS88819.1 - 1.3e-33 116.0 0.0 1.7e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 RUS88819.1 - 4.8e-09 37.2 0.0 7.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RUS88819.1 - 8.9e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RUS88819.1 - 0.00055 19.8 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 RUS88819.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 RUS88819.1 - 0.013 16.2 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 RUS88819.1 - 0.059 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RVT_1 PF00078.27 RUS88821.1 - 6.3e-44 150.1 0.5 1.4e-43 149.0 0.5 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_phi PF04931.13 RUS88823.1 - 1.5 6.8 10.9 1.9 6.5 10.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RUS88824.1 - 6.6e-06 25.7 30.3 8.4e-06 25.4 30.3 1.1 1 0 0 1 1 1 1 BUD22 AP3D1 PF06375.11 RUS88824.1 - 0.00067 19.9 15.6 0.00067 19.9 15.6 3.1 2 1 0 2 2 1 1 AP-3 complex subunit delta-1 DUF3464 PF11947.8 RUS88824.1 - 0.0011 18.8 6.2 0.3 10.9 9.0 2.2 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Nop14 PF04147.12 RUS88824.1 - 0.0036 15.6 43.4 0.0044 15.3 43.4 1.0 1 0 0 1 1 1 1 Nop14-like family ORC5_C PF14630.6 RUS88824.1 - 0.0074 15.8 0.4 0.01 15.4 0.4 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus NPR3 PF03666.13 RUS88824.1 - 0.0079 15.0 14.2 0.02 13.7 0.9 2.0 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 CENP-B_dimeris PF09026.10 RUS88824.1 - 0.011 16.1 7.5 0.011 16.1 7.5 3.3 2 1 0 2 2 1 0 Centromere protein B dimerisation domain SR-25 PF10500.9 RUS88824.1 - 0.012 15.2 12.7 0.016 14.8 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.14 RUS88824.1 - 0.014 16.3 0.5 0.029 15.3 0.5 1.5 1 0 0 1 1 1 0 E4 protein DUF1168 PF06658.12 RUS88824.1 - 0.018 14.9 12.6 0.018 14.9 12.6 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.12 RUS88824.1 - 0.018 14.8 12.9 0.018 14.8 12.9 3.1 2 1 1 3 3 1 0 Cwf15/Cwc15 cell cycle control protein Afi1 PF07792.12 RUS88824.1 - 0.02 15.4 24.8 0.18 12.3 7.4 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S49_N PF08496.10 RUS88824.1 - 0.03 14.4 5.9 0.044 13.8 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 RUS88824.1 - 0.032 14.8 6.7 0.032 14.8 6.7 2.4 3 1 0 3 3 1 0 Oxaloacetate decarboxylase, gamma chain AIM3 PF17096.5 RUS88824.1 - 0.033 15.1 5.8 0.033 15.1 5.8 3.0 2 1 0 2 2 1 0 Altered inheritance of mitochondria protein 3 Connexin PF00029.19 RUS88824.1 - 0.098 12.4 0.0 1.3 8.7 1.2 1.9 2 0 0 2 2 2 0 Connexin TerC PF03741.16 RUS88824.1 - 0.1 12.3 1.6 1.5 8.5 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein TerC family DUF1387 PF07139.11 RUS88824.1 - 0.12 12.1 12.5 0.15 11.8 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) V_ATPase_I PF01496.19 RUS88824.1 - 0.19 9.6 5.9 0.29 9.0 5.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family BSP_II PF05432.11 RUS88824.1 - 0.76 9.4 17.8 1.4 8.5 3.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFB6 PF17110.5 RUS88824.1 - 1.2 8.9 25.7 0.15 11.8 2.3 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF3537 PF12056.8 RUS88824.1 - 1.3 7.7 5.1 1.1 8.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) DUF2956 PF11169.8 RUS88824.1 - 1.6 9.0 13.4 4.8 7.4 13.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Orf78 PF06024.12 RUS88824.1 - 5.4 7.4 15.4 0.52 10.6 3.5 2.4 2 1 0 2 2 2 0 Orf78 (ac78) DUF4710 PF15828.5 RUS88824.1 - 7 6.9 20.4 16 5.7 20.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) MAP17 PF15807.5 RUS88824.1 - 9 6.6 6.9 15 5.8 5.4 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 cNMP_binding PF00027.29 RUS88827.1 - 0.098 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain 7tm_1 PF00001.21 RUS88828.1 - 3e-16 59.5 1.1 3.7e-16 59.2 1.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glucan_synthase PF02364.15 RUS88828.1 - 0.05 11.8 0.5 0.067 11.3 0.5 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component HemY_N PF07219.13 RUS88828.1 - 2.5 8.3 4.6 12 6.1 0.2 2.6 3 0 0 3 3 3 0 HemY protein N-terminus Acyl_transf_3 PF01757.22 RUS88829.1 - 6.3e-09 35.3 8.5 6.3e-09 35.3 8.5 2.0 1 1 1 2 2 2 2 Acyltransferase family Acyl_transf_3 PF01757.22 RUS88830.1 - 1.1e-25 90.4 36.8 1.7e-25 89.8 36.8 1.2 1 0 0 1 1 1 1 Acyltransferase family YjbT PF17089.5 RUS88830.1 - 0.086 12.9 0.4 0.81 9.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family Peptidase_C13 PF01650.18 RUS88831.1 - 6.2e-52 176.7 2.9 1.1e-41 143.1 0.3 2.0 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C13 PF01650.18 RUS88832.1 - 4.3e-52 177.2 0.2 5.9e-52 176.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Integrase_H2C2 PF17921.1 RUS88832.1 - 2.7e-10 40.2 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 RUS88832.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Peptidase_C13 PF01650.18 RUS88834.1 - 6.6e-108 360.0 0.0 8.6e-108 359.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Lipase PF00151.19 RUS88835.1 - 2.7e-77 260.4 0.0 3.4e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 RUS88835.1 - 0.0087 16.7 0.1 0.012 16.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 RUS88835.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 RUS88835.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_2 PF01674.18 RUS88835.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Y_phosphatase PF00102.27 RUS88836.1 - 5.8e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 RUS88837.1 - 1.2e-27 97.0 0.0 2.8e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 RUS88838.1 - 7.5e-32 110.8 2.7 1e-31 110.3 2.7 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase tRNA_edit PF04073.15 RUS88839.1 - 0.34 11.0 0.4 12 6.0 0.1 2.1 2 0 0 2 2 2 0 Aminoacyl-tRNA editing domain DUF572 PF04502.13 RUS88842.1 - 0.13 11.9 13.2 0.12 12.0 11.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) CLP_protease PF00574.23 RUS88842.1 - 1.1 9.2 5.4 1.8 8.4 5.4 1.2 1 0 0 1 1 1 0 Clp protease MIF4G_like_2 PF09090.11 RUS88842.1 - 6.3 6.2 11.0 15 5.0 9.2 2.0 2 0 0 2 2 2 0 MIF4G like Exonuc_VII_L PF02601.15 RUS88842.1 - 6.6 6.2 13.1 1.8 8.1 8.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Membralin PF09746.9 RUS88843.1 - 2.7e-155 517.2 10.4 7.4e-118 393.9 4.6 2.1 1 1 1 2 2 2 2 Tumour-associated protein VWA_2 PF13519.6 RUS88844.1 - 4.7e-06 27.2 0.0 6.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RUS88844.1 - 0.032 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Vps55 PF04133.14 RUS88845.1 - 1.1e-41 141.4 6.5 1.3e-41 141.2 6.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Bax1-I PF01027.20 RUS88845.1 - 0.19 11.5 8.5 0.22 11.3 8.5 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CAML PF14963.6 RUS88845.1 - 0.3 11.2 0.3 0.36 10.9 0.3 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand 3HCDH_N PF02737.18 RUS88846.1 - 7.5e-58 195.4 1.1 1.3e-57 194.6 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 RUS88846.1 - 3.5e-36 124.8 0.1 5.8e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 RUS88846.1 - 8.2e-28 96.9 0.2 1.6e-22 79.9 0.1 3.2 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 RUS88846.1 - 2.4e-23 83.2 0.1 4.2e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 RUS88846.1 - 0.046 13.9 0.2 0.16 12.1 0.2 2.0 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TPR_MLP1_2 PF07926.12 RUS88847.1 - 1.2e-26 93.3 29.4 1.2e-26 93.3 29.4 17.5 8 4 5 15 15 15 6 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 RUS88847.1 - 0.0055 17.0 23.7 0.0055 17.0 23.7 16.8 4 3 9 15 15 15 5 Autophagy protein 16 (ATG16) DUF2939 PF11159.8 RUS88847.1 - 1.6 9.2 5.7 2.7 8.5 1.3 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) ArsA_ATPase PF02374.15 RUS88848.1 - 2.8e-119 397.9 0.2 3.2e-119 397.7 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 RUS88848.1 - 1.4e-10 41.4 0.2 6.7e-10 39.2 0.0 2.2 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 RUS88848.1 - 1.7e-10 41.0 0.1 1.2e-09 38.3 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RUS88848.1 - 3.3e-05 23.5 0.0 6.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 RUS88848.1 - 0.00025 20.6 0.3 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 RUS88848.1 - 0.00032 20.3 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 RUS88848.1 - 0.0041 16.8 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 RUS88848.1 - 0.047 13.3 0.4 0.23 11.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RUS88848.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Elf1 PF05129.13 RUS88848.1 - 0.055 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zeta_toxin PF06414.12 RUS88848.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin YlbD_coat PF14071.6 RUS88848.1 - 1 9.6 3.2 0.74 10.1 0.7 2.0 3 0 0 3 3 3 0 Putative coat protein PDCD9 PF07147.12 RUS88849.1 - 1.4e-23 83.9 0.0 1.6e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) RPAP3_C PF13877.6 RUS88853.1 - 0.0011 19.4 0.3 7.3 7.2 0.0 3.6 1 1 2 3 3 3 2 Potential Monad-binding region of RPAP3 CARMIL_C PF16000.5 RUS88853.1 - 0.006 16.3 0.9 4.7 6.7 0.0 3.1 2 1 2 4 4 4 2 CARMIL C-terminus ARID PF01388.21 RUS88853.1 - 0.033 14.8 3.5 17 6.1 0.3 3.2 1 1 2 3 3 3 0 ARID/BRIGHT DNA binding domain Sec7_N PF12783.7 RUS88853.1 - 0.28 11.1 1.8 12 5.7 0.9 3.5 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal KNOX1 PF03790.13 RUS88853.1 - 1.9 8.3 16.0 37 4.2 0.0 6.7 2 2 5 8 8 8 0 KNOX1 domain 7tm_1 PF00001.21 RUS88854.1 - 2.5e-26 92.6 14.4 3.1e-26 92.3 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS88854.1 - 1.5e-08 34.6 6.1 3.1e-08 33.6 6.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx PUL PF08324.11 RUS88855.1 - 1.2e-43 149.4 0.0 1.7e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 RUS88855.1 - 6e-43 145.7 0.1 1.1e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 RUS88855.1 - 5.4e-34 115.7 9.8 1.2e-05 25.9 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 RUS88855.1 - 0.00011 22.2 0.0 0.085 12.9 0.0 3.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Peptidase_M23 PF01551.22 RUS88855.1 - 0.11 12.7 0.5 0.47 10.7 0.2 2.1 2 0 0 2 2 2 0 Peptidase family M23 Arrestin_N PF00339.29 RUS88856.1 - 1.9e-27 96.1 0.0 5e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS88856.1 - 3.1e-17 63.3 0.0 2.5e-12 47.4 0.0 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain RAP1 PF07218.11 RUS88856.1 - 6.3 5.0 8.3 9.8 4.3 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lipocalin_2 PF08212.12 RUS88857.1 - 0.019 14.9 0.0 7 6.6 0.0 2.9 1 1 2 3 3 3 0 Lipocalin-like domain PDZ_1 PF12812.7 RUS88857.1 - 0.023 14.7 1.1 9.5 6.3 0.0 3.7 1 1 3 4 4 4 0 PDZ-like domain DUF2920 PF11144.8 RUS88857.1 - 0.15 11.2 0.5 13 4.8 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2920) Pneumo_M2 PF07380.11 RUS88857.1 - 0.24 11.7 5.1 8.3 6.8 0.2 3.1 1 1 2 3 3 3 0 Pneumovirus M2 protein DUF3948 PF13134.6 RUS88857.1 - 0.9 9.3 15.9 1.1e+02 2.6 0.0 7.6 8 1 1 9 9 9 0 Protein of unknown function (DUF3948) ICMT PF04140.14 RUS88860.1 - 1.1e-24 86.7 2.8 1.5e-24 86.2 0.3 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RUS88860.1 - 1.8e-07 31.5 0.8 1.8e-07 31.5 0.8 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase LRR_9 PF14580.6 RUS88861.1 - 7e-07 28.9 0.2 1.1e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RUS88861.1 - 4e-06 27.1 11.5 0.0021 18.4 0.6 3.7 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS88861.1 - 7.7e-05 22.4 6.8 0.023 14.4 0.2 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 RUS88861.1 - 3.5 8.6 9.3 28 5.8 0.0 4.4 3 2 1 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 RUS88862.1 - 8.2e-13 48.6 13.7 0.053 14.4 0.0 8.3 7 2 1 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS88862.1 - 1.8e-12 47.4 1.8 0.0033 17.7 0.0 6.3 2 2 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RUS88862.1 - 7.4e-11 42.3 0.0 0.22 11.4 0.0 5.5 2 2 4 6 6 6 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 RUS88862.1 - 0.0016 16.6 0.6 3.7 5.4 1.1 3.7 2 1 0 2 2 2 2 IKI3 family PD40 PF07676.12 RUS88862.1 - 0.0019 18.1 0.7 6.9 6.7 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 RUS88862.1 - 0.065 12.9 0.5 6.8 6.5 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature P53 PF00870.18 RUS88863.1 - 9.9e-65 217.9 0.0 1.5e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.11 RUS88863.1 - 9e-13 47.3 0.1 2.1e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.17 RUS88863.1 - 6.2e-11 42.2 0.1 2.5e-10 40.3 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS88863.1 - 1.7e-08 34.8 0.1 3.8e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FAM92 PF06730.11 RUS88863.1 - 0.18 11.2 0.2 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 FAM92 protein NHL PF01436.21 RUS88864.1 - 6.1e-18 63.9 2.3 1.2e-05 25.0 0.0 5.2 4 0 0 4 4 4 4 NHL repeat Filamin PF00630.19 RUS88864.1 - 4.4e-10 40.3 0.0 1.8e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 RUS88864.1 - 1.8e-07 31.2 2.5 1.8e-07 31.2 2.5 3.4 4 0 0 4 4 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 RUS88864.1 - 9.5e-07 28.7 4.6 9.5e-07 28.7 4.6 3.9 4 1 1 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 RUS88864.1 - 2.4e-06 27.7 8.4 2.4e-06 27.7 8.4 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 RUS88864.1 - 4.5e-06 26.5 8.3 4.5e-06 26.5 8.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS88864.1 - 2.9e-05 23.8 7.2 2.9e-05 23.8 7.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS88864.1 - 3.6e-05 23.5 7.7 3.6e-05 23.5 7.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 RUS88864.1 - 0.00023 20.4 0.8 0.18 10.9 0.0 2.7 1 1 1 2 2 2 2 6-bladed beta-propeller Prok-RING_4 PF14447.6 RUS88864.1 - 0.00034 20.4 7.2 0.00034 20.4 7.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Invasin_D3 PF09134.10 RUS88864.1 - 0.00074 19.8 0.1 0.0027 18.0 0.0 1.9 2 0 0 2 2 2 1 Invasin, domain 3 zf-C3HC4_4 PF15227.6 RUS88864.1 - 0.0031 17.6 1.8 0.0031 17.6 1.8 3.2 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RUS88864.1 - 0.012 15.3 7.2 0.012 15.3 7.2 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SGL PF08450.12 RUS88864.1 - 0.023 14.3 0.1 8.2 5.9 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region zf-C3HC4_2 PF13923.6 RUS88864.1 - 0.97 9.3 18.2 0.23 11.3 8.5 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.12 RUS88864.1 - 1.4 9.0 4.3 3.2 7.8 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LSM PF01423.22 RUS88865.1 - 1.5e-10 40.6 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RUS88865.1 - 0.056 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FAM194 PF14977.6 RUS88865.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 FAM194 protein GMP_PDE_delta PF05351.11 RUS88866.1 - 4.7e-45 153.5 0.0 6.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit PsbQ PF05757.11 RUS88867.1 - 0.084 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) EF-hand_7 PF13499.6 RUS88867.1 - 0.088 13.3 0.1 0.38 11.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair Strep_pep PF14404.6 RUS88871.1 - 0.3 11.4 0.9 49 4.3 0.1 3.5 1 1 3 4 4 4 0 Ribosomally synthesized peptide in Streptomyces species Dynein_IC2 PF11540.8 RUS88871.1 - 0.68 9.9 10.6 78 3.4 0.0 5.3 5 0 0 5 5 5 0 Cytoplasmic dynein 1 intermediate chain 2 Fer4_3 PF12798.7 RUS88871.1 - 9.9 7.4 30.3 4.8 8.4 0.4 5.7 5 0 0 5 5 5 0 4Fe-4S binding domain EF-hand_1 PF00036.32 RUS88872.1 - 4.6e-10 38.3 1.5 4.7e-05 22.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RUS88872.1 - 1.5e-08 34.9 2.7 1.5e-08 34.9 2.7 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS88872.1 - 3.9e-08 32.6 2.2 0.0014 18.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 RUS88872.1 - 5.8e-08 32.5 2.1 0.0017 18.1 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS88872.1 - 2.2e-07 30.1 2.8 0.00076 18.9 0.5 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 RUS88872.1 - 0.0015 18.9 0.2 0.0015 18.9 0.2 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Spore_coat_CotO PF14153.6 RUS88872.1 - 0.0035 17.3 3.7 0.0046 16.9 3.7 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Autophagy_N PF03986.13 RUS88872.1 - 0.019 14.9 3.0 0.034 14.1 2.7 1.5 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain Dockerin_1 PF00404.18 RUS88872.1 - 0.049 13.8 0.7 1.5 9.0 0.4 2.3 1 1 1 2 2 2 0 Dockerin type I domain Isy1 PF06246.12 RUS88872.1 - 0.053 13.1 5.8 0.083 12.4 5.8 1.3 1 0 0 1 1 1 0 Isy1-like splicing family DUF5580 PF17743.1 RUS88872.1 - 0.42 9.1 4.4 2.7 6.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5580) Pox_Ag35 PF03286.14 RUS88872.1 - 0.55 10.0 7.0 0.81 9.4 7.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.16 RUS88872.1 - 2.5 7.5 4.1 3.4 7.1 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TPD52 PF04201.15 RUS88873.1 - 1.8e-39 135.0 13.7 4.4e-21 75.2 1.3 2.1 1 1 1 2 2 2 2 Tumour protein D52 family VasL PF12486.8 RUS88873.1 - 0.0025 17.7 0.8 0.0025 17.7 0.8 1.5 2 0 0 2 2 1 1 Type VI secretion system, EvfB, or VasL ALIX_LYPXL_bnd PF13949.6 RUS88873.1 - 0.008 15.5 3.9 0.011 15.0 3.9 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV LemA PF04011.12 RUS88873.1 - 0.015 15.2 3.8 4.3 7.2 1.6 2.6 1 1 0 2 2 2 0 LemA family DUF4763 PF15960.5 RUS88873.1 - 0.04 13.2 4.3 0.1 11.9 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Med9 PF07544.13 RUS88873.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.7 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Dopey_N PF04118.14 RUS88873.1 - 0.046 12.8 0.3 0.064 12.4 0.3 1.2 1 0 0 1 1 1 0 Dopey, N-terminal Goodbye PF17109.5 RUS88873.1 - 0.32 11.5 3.7 0.32 11.5 1.8 1.9 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain PIN_8 PF18476.1 RUS88873.1 - 0.48 10.3 6.2 0.84 9.4 1.1 1.9 1 1 1 2 2 2 0 PIN like domain DivIC PF04977.15 RUS88873.1 - 0.58 10.0 4.4 6.6 6.6 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Swi5 PF07061.11 RUS88873.1 - 0.7 10.0 5.9 2.4 8.3 4.7 2.3 1 1 1 2 2 2 0 Swi5 COG2 PF06148.11 RUS88873.1 - 1.1 9.4 6.6 2.4 8.3 0.8 2.5 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBCA PF02970.16 RUS88873.1 - 1.2 9.5 6.2 5.9 7.3 0.7 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A PspA_IM30 PF04012.12 RUS88873.1 - 1.5 8.3 10.7 5.6 6.5 6.2 2.0 1 1 1 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.8 RUS88873.1 - 1.8 8.6 6.8 1.2 9.2 0.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.6 RUS88873.1 - 2.3 6.7 12.3 1.9 7.0 5.8 2.0 1 1 1 2 2 2 0 AAA domain V-SNARE PF05008.15 RUS88873.1 - 2.9 8.3 7.2 14 6.2 1.2 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.13 RUS88873.1 - 2.9 8.7 6.6 5.1 7.9 2.1 2.5 1 1 1 2 2 2 0 Occludin homology domain GST_N_3 PF13417.6 RUS88874.1 - 1.5e-17 63.7 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS88874.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS88874.1 - 1.1e-13 51.2 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS88874.1 - 2.2e-06 27.6 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RUS88874.1 - 7.1e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 RUS88874.1 - 0.0004 20.5 0.0 0.00081 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS88874.1 - 0.006 16.8 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RUS88874.1 - 0.096 12.5 0.0 0.38 10.6 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DLH PF01738.18 RUS88875.1 - 1.7e-44 151.9 0.0 2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 RUS88875.1 - 0.027 13.2 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 RUS88875.1 - 0.047 14.3 0.0 0.098 13.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 RUS88875.1 - 0.41 10.5 2.6 2.2 8.1 0.3 2.4 1 1 2 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3123 PF11321.8 RUS88877.1 - 9.5 6.9 12.0 3 8.6 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Reprolysin PF01421.19 RUS88878.1 - 6.2e-10 39.3 0.2 1.9e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 RUS88878.1 - 2.8e-09 37.4 5.9 2.8e-09 37.4 5.9 2.3 3 0 0 3 3 3 1 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 RUS88878.1 - 3.3e-08 34.1 0.1 3.3e-08 34.1 0.1 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS88878.1 - 7.9e-08 32.7 1.1 7.9e-08 32.7 1.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RUS88878.1 - 1.1e-05 25.4 0.6 1.1e-05 25.4 0.6 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS88878.1 - 0.00024 20.8 0.6 0.00024 20.8 0.6 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Mucin PF01456.17 RUS88878.1 - 0.0065 16.5 43.1 0.0065 16.5 43.1 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.12 RUS88878.1 - 0.52 8.2 9.7 0.96 7.4 9.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPX PF03105.19 RUS88878.1 - 1.7 8.5 7.1 2.9 7.7 7.1 1.3 1 0 0 1 1 1 0 SPX domain Wzy_C_2 PF11846.8 RUS88879.1 - 0.027 14.4 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ADAM_CR_2 PF17771.1 RUS88880.1 - 3.8e-08 33.7 6.3 8.1e-08 32.7 6.3 1.6 1 0 0 1 1 1 1 ADAM cysteine-rich domain Shikimate_dh_N PF08501.11 RUS88882.1 - 0.096 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain TPR_19 PF14559.6 RUS88885.1 - 0.019 15.4 0.2 49 4.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS88885.1 - 0.021 14.9 1.9 7.8 6.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Alginate_exp PF13372.6 RUS88885.1 - 0.035 12.8 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Alginate export TPR_8 PF13181.6 RUS88885.1 - 0.042 14.1 0.3 12 6.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SAD_SRA PF02182.17 RUS88885.1 - 0.077 12.7 0.3 6.7 6.4 0.0 2.5 2 1 0 2 2 2 0 SAD/SRA domain TPR_11 PF13414.6 RUS88885.1 - 0.078 12.7 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 RUS88885.1 - 0.26 11.6 3.4 3.1 8.1 0.3 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 RUS88886.1 - 0.023 15.1 1.9 5.1 7.7 0.4 2.8 2 1 0 2 2 2 0 Zinc-finger double domain DUF3656 PF12392.8 RUS88886.1 - 0.045 14.4 0.0 5.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Collagenase XendoU PF09412.10 RUS88888.1 - 6e-64 215.8 0.0 7.3e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU SRCR PF00530.18 RUS88889.1 - 3.1e-14 53.3 1.4 2.1e-07 31.4 0.4 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ldl_recept_a PF00057.18 RUS88889.1 - 7.9e-11 42.0 12.0 7.9e-11 42.0 12.0 2.6 2 1 1 3 3 3 1 Low-density lipoprotein receptor domain class A Redoxin PF08534.10 RUS88890.1 - 1.8e-06 27.7 0.1 2 8.1 0.0 3.8 1 1 4 5 5 5 5 Redoxin DUF5598 PF18127.1 RUS88890.1 - 0.00048 20.5 15.7 13 6.3 0.3 4.8 1 1 4 5 5 5 5 Domain of unknown function (DUF5598) PHBC_N PF12551.8 RUS88890.1 - 0.0013 18.5 8.0 3.4e+02 1.1 0.0 8.5 10 0 0 10 10 10 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF4998 PF16389.5 RUS88890.1 - 0.0027 17.3 2.4 48 3.5 0.0 4.6 1 1 6 7 7 7 0 Domain of unknown function DUF3926 PF13080.6 RUS88890.1 - 0.0045 16.9 12.3 66 3.6 0.7 7.2 1 1 8 9 9 9 0 Protein of unknown function (DUF3926) Aldo_ket_red PF00248.21 RUS88891.1 - 3.2e-54 184.1 0.0 4.2e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CUB PF00431.20 RUS88892.1 - 1.5e-09 38.1 0.1 2.3e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 CUB domain DUF4690 PF15756.5 RUS88892.1 - 0.09 13.4 0.0 0.33 11.6 0.0 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage CUB PF00431.20 RUS88893.1 - 3.4e-05 24.1 0.1 0.00012 22.4 0.0 1.8 2 0 0 2 2 2 1 CUB domain TatD_DNase PF01026.21 RUS88894.1 - 4.3e-54 183.6 0.0 5.9e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 RUS88894.1 - 8.9e-05 22.4 0.3 0.00055 19.8 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Mt_ATP-synt_B PF05405.14 RUS88896.1 - 5.7 6.5 16.3 7.1 6.2 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CAF-1_p150 PF11600.8 RUS88896.1 - 7.1 6.3 45.2 15 5.2 33.4 1.9 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EF-hand_1 PF00036.32 RUS88897.1 - 3.3e-21 73.2 11.5 2.9e-09 35.8 2.6 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS88897.1 - 2.4e-19 69.5 4.8 8.9e-17 61.3 3.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS88897.1 - 9.9e-16 56.3 5.5 2.4e-08 33.2 1.6 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RUS88897.1 - 1.1e-15 56.3 4.5 1.9e-07 30.2 0.7 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RUS88897.1 - 2.2e-15 56.2 12.0 4.5e-14 52.0 3.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 RUS88897.1 - 5.9e-06 26.5 1.3 7.3e-06 26.2 0.5 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 RUS88897.1 - 4.1e-05 24.4 0.1 7.4e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS88897.1 - 0.00057 20.2 0.8 0.00086 19.6 0.8 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RUS88897.1 - 0.0011 18.9 1.9 0.051 13.5 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 RUS88897.1 - 0.026 14.5 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 RUS88897.1 - 0.17 12.1 0.3 0.41 10.9 0.3 1.7 1 1 0 1 1 1 0 Dockerin type I domain Styelin PF17562.2 RUS88897.1 - 0.3 11.5 3.8 0.55 10.6 2.3 2.1 1 1 1 2 2 2 0 Styelin MTS PF05175.14 RUS88899.1 - 1.4e-11 44.3 0.0 4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RUS88899.1 - 7.5e-08 33.0 0.0 2e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS88899.1 - 5e-07 29.6 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS88899.1 - 5.2e-05 23.9 0.0 0.00012 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RUS88899.1 - 0.00034 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 RUS88899.1 - 0.00063 20.7 0.0 0.0015 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS88899.1 - 0.00068 19.5 0.0 0.0045 16.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS88899.1 - 0.00073 20.1 0.0 0.0019 18.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 RUS88899.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain UPF0020 PF01170.18 RUS88899.1 - 0.0045 16.7 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CholecysA-Rec_N PF09193.10 RUS88899.1 - 0.01 15.8 1.0 4.5 7.4 0.3 2.5 1 1 1 2 2 2 0 Cholecystokinin A receptor, N-terminal MRF_C1 PF13887.6 RUS88899.1 - 0.1 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DUF938 PF06080.12 RUS88899.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) N6-adenineMlase PF10237.9 RUS88899.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase LPMO_10 PF03067.15 RUS88900.1 - 0.012 16.3 0.0 0.017 15.8 0.0 1.4 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 RUS88901.1 - 0.063 13.9 0.0 0.6 10.7 0.0 2.4 2 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF2512 PF10710.9 RUS88901.1 - 0.14 11.8 0.2 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Ogr_Delta PF04606.12 RUS88901.1 - 0.17 11.9 1.5 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Sen15 PF09631.10 RUS88901.1 - 0.19 12.0 0.3 2.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Sen15 protein VCH_CASS14 PF18315.1 RUS88902.1 - 2.1e-07 30.9 7.7 0.54 10.4 0.1 4.7 1 1 4 5 5 5 4 Integron cassette protein VCH_CASS1 chain Pectate_lyase_3 PF12708.7 RUS88902.1 - 5.1e-05 23.2 5.8 1.7 8.5 2.7 4.5 1 1 2 3 3 3 2 Pectate lyase superfamily protein Pab87_oct PF13969.6 RUS88902.1 - 0.0024 17.9 3.5 0.66 10.1 0.1 2.6 1 1 2 3 3 3 2 Pab87 octamerisation domain Ntox35 PF15534.6 RUS88902.1 - 0.0067 16.8 12.0 34 5.0 0.4 5.9 1 1 6 7 7 7 0 Bacterial toxin 35 TRCF PF03461.15 RUS88902.1 - 0.016 15.5 0.0 1.4e+02 3.0 0.0 3.8 1 1 4 5 5 5 0 TRCF domain Torus PF16131.5 RUS88902.1 - 0.07 13.8 1.7 46 4.8 0.0 3.9 2 1 3 5 5 5 0 Torus domain DDE_Tnp_IS240 PF13610.6 RUS88902.1 - 0.21 11.8 5.7 72 3.6 0.0 5.4 2 1 4 7 7 7 0 DDE domain CAP_C PF08603.11 RUS88902.1 - 1.9 8.1 8.1 25 4.5 0.3 3.0 1 1 2 3 3 3 0 Adenylate cyclase associated (CAP) C terminal Ribosomal_S11 PF00411.19 RUS88902.1 - 3 8.3 4.6 35 4.9 0.2 3.4 1 1 3 4 4 4 0 Ribosomal protein S11 S_locus_glycop PF00954.20 RUS88902.1 - 8.5 6.9 8.9 17 6.0 0.3 3.0 1 1 2 3 3 3 0 S-locus glycoprotein domain Frizzled PF01534.17 RUS88904.1 - 5.8e-75 252.3 10.7 8.9e-75 251.7 10.7 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RUS88904.1 - 6.9e-15 55.6 0.7 1.6e-14 54.4 0.7 1.7 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 RUS88904.1 - 7.2e-05 22.2 9.2 7.2e-05 22.2 9.2 2.2 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) ANAPC4_WD40 PF12894.7 RUS88905.1 - 8.6e-10 38.8 4.6 7.6e-05 22.9 0.1 5.4 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RUS88905.1 - 3e-07 29.9 2.5 0.00013 21.2 0.1 3.0 2 0 0 2 2 2 2 Coatomer WD associated region Clathrin PF00637.20 RUS88905.1 - 7.9e-07 29.0 5.4 2.5e-05 24.2 0.4 3.5 1 1 2 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 RUS88905.1 - 0.0016 19.3 1.1 7 7.7 0.0 5.1 6 1 1 7 7 5 1 WD domain, G-beta repeat TPR_7 PF13176.6 RUS88905.1 - 0.045 13.8 5.3 3.1 8.0 0.3 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 RUS88905.1 - 0.16 12.0 12.7 4.8 7.3 12.8 2.7 1 1 0 1 1 1 0 Double zinc ribbon DUF3090 PF11290.8 RUS88905.1 - 0.2 11.5 1.3 0.81 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) TPR_1 PF00515.28 RUS88905.1 - 0.58 10.1 4.5 39 4.3 0.3 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 RUS88905.1 - 1.6 8.3 10.4 0.091 12.2 3.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TPR_2 PF07719.17 RUS88905.1 - 1.9 8.8 14.7 2.3 8.5 0.4 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 RUS88905.1 - 2.5 8.8 11.7 4.3 8.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Rubredoxin_2 PF18073.1 RUS88905.1 - 9.2 6.1 8.9 2.8 7.8 1.8 3.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Thioredoxin PF00085.20 RUS88906.1 - 2.9e-95 313.1 2.7 1.3e-32 111.9 0.1 3.1 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 RUS88906.1 - 3.5e-17 62.8 0.7 3.1e-05 24.4 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS88906.1 - 4.9e-13 49.2 0.0 0.03 14.6 0.0 5.1 3 2 2 5 5 5 3 Thioredoxin-like OST3_OST6 PF04756.13 RUS88906.1 - 3.7e-10 39.6 0.0 0.027 13.8 0.0 3.2 1 1 1 3 3 3 3 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RUS88906.1 - 4.4e-09 36.3 1.7 0.042 13.8 0.1 3.2 3 0 0 3 3 3 3 AhpC/TSA family TraF PF13728.6 RUS88906.1 - 4.4e-08 33.2 0.1 0.049 13.4 0.0 3.4 3 1 0 3 3 3 3 F plasmid transfer operon protein HyaE PF07449.11 RUS88906.1 - 1.3e-06 28.3 0.0 0.023 14.6 0.0 4.0 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 RUS88906.1 - 1.6e-06 28.2 2.4 1.5 9.0 0.1 3.9 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_3 PF13192.6 RUS88906.1 - 1.1e-05 25.3 3.7 0.15 12.1 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin domain Thioredoxin_9 PF14595.6 RUS88906.1 - 1.3e-05 25.0 0.5 2.2 8.1 0.1 3.5 2 1 1 3 3 3 3 Thioredoxin Redoxin PF08534.10 RUS88906.1 - 0.002 17.9 3.2 5 6.8 0.1 3.3 3 0 0 3 3 3 2 Redoxin Calsequestrin PF01216.17 RUS88906.1 - 0.0035 16.5 0.6 0.12 11.4 0.2 2.6 2 1 1 3 3 3 1 Calsequestrin Glutaredoxin PF00462.24 RUS88906.1 - 0.0078 16.4 7.6 1.4 9.2 0.1 4.0 3 1 0 3 3 3 1 Glutaredoxin UCH_1 PF13423.6 RUS88906.1 - 0.15 11.6 0.8 4 6.9 0.8 2.8 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Thioredoxin PF00085.20 RUS88907.1 - 7.6e-64 212.2 0.0 6.3e-31 106.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 RUS88907.1 - 1.9e-07 31.5 1.1 0.073 13.5 0.0 4.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 RUS88907.1 - 3.4e-06 27.1 0.0 0.33 10.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RUS88907.1 - 4.8e-05 23.6 0.0 0.18 12.1 0.0 3.6 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 RUS88907.1 - 0.00041 20.5 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 RUS88907.1 - 0.0018 18.3 0.0 0.7 10.0 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin domain OST3_OST6 PF04756.13 RUS88907.1 - 0.0028 17.1 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 RUS88907.1 - 0.036 14.0 0.0 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family DUF3228 PF11539.8 RUS88907.1 - 0.22 11.0 0.0 13 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) CD20 PF04103.15 RUS88908.1 - 2e-05 24.7 7.1 3.8e-05 23.8 6.5 1.7 1 1 0 1 1 1 1 CD20-like family DUF308 PF03729.13 RUS88908.1 - 0.004 17.5 8.7 1.3 9.4 0.0 3.2 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 RUS88908.1 - 0.0092 16.0 0.1 0.0092 16.0 0.1 2.5 1 1 1 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_3_7 PF05449.11 RUS88908.1 - 0.033 14.2 0.4 0.089 12.8 0.4 1.7 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 MARVEL PF01284.23 RUS88908.1 - 0.043 13.9 1.9 0.056 13.5 0.6 1.8 2 0 0 2 2 2 0 Membrane-associating domain Fumarate_red_C PF02300.17 RUS88908.1 - 0.061 13.4 1.4 0.12 12.5 1.4 1.5 1 1 0 1 1 1 0 Fumarate reductase subunit C MIG-14_Wnt-bd PF06664.12 RUS88908.1 - 0.074 12.3 2.9 0.1 11.8 2.9 1.3 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4199 PF13858.6 RUS88908.1 - 0.16 12.4 7.7 0.23 11.8 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SdpI PF13630.6 RUS88908.1 - 1.2 9.3 8.5 1.7 8.8 1.6 3.1 2 1 1 3 3 3 0 SdpI/YhfL protein family Tetraspanin PF00335.20 RUS88908.1 - 1.6 8.4 6.1 3.3 7.4 6.2 1.6 1 1 0 1 1 1 0 Tetraspanin family MIR PF02815.19 RUS88909.1 - 5.7e-14 52.4 3.6 3.6e-09 36.7 0.3 2.6 1 1 2 3 3 3 3 MIR domain E7 PF00527.18 RUS88909.1 - 0.066 13.4 3.9 5.8 7.2 0.0 2.6 2 1 0 2 2 2 0 E7 protein, Early protein Toxin_24 PF08094.11 RUS88909.1 - 0.17 11.7 0.4 0.4 10.5 0.4 1.5 1 0 0 1 1 1 0 Conotoxin TVIIA/GS family Kinesin PF00225.23 RUS88910.1 - 8.5e-109 363.5 0.2 1.4e-108 362.8 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 RUS88910.1 - 4e-28 98.8 5.4 5.4e-20 72.3 0.4 3.1 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 RUS88910.1 - 1.5e-25 90.6 0.0 4.8e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 RUS88910.1 - 1.2e-22 80.4 0.4 3.6e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 RUS88910.1 - 2.3e-15 56.7 0.4 1e-14 54.7 0.1 2.4 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 RUS88910.1 - 1.5e-08 34.8 0.1 5.4e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 RUS88910.1 - 0.00033 20.9 0.0 0.00095 19.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3585 PF12130.8 RUS88910.1 - 0.00058 20.0 1.4 0.00058 20.0 1.4 3.4 3 1 0 3 3 3 1 Bivalent Mical/EHBP Rab binding domain LRR_8 PF13855.6 RUS88911.1 - 6.4e-35 118.7 16.6 2.1e-11 43.4 4.4 6.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS88911.1 - 1.6e-13 50.6 16.9 3e-05 24.3 0.2 6.6 2 1 5 8 8 8 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS88911.1 - 9.9e-13 48.2 0.0 9.6e-06 25.6 0.1 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS88911.1 - 6.5e-07 29.0 13.2 1.5 9.6 0.1 7.9 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS88911.1 - 0.015 14.8 0.4 0.088 12.3 0.1 2.2 1 1 0 2 2 2 0 Leucine-rich repeat Lactococcin_972 PF09683.10 RUS88912.1 - 0.39 11.3 3.5 0.46 11.1 0.1 2.8 3 0 0 3 3 3 0 Bacteriocin (Lactococcin_972) Htr2 PF17909.1 RUS88912.1 - 0.82 10.0 5.1 1.4 9.2 5.1 1.3 1 0 0 1 1 1 0 Htr2 transmembrane domain UPF0560 PF10577.9 RUS88913.1 - 0.072 11.6 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CAP_GLY PF01302.25 RUS88915.1 - 1.2e-23 82.9 0.1 2.1e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain PhyH PF05721.13 RUS88917.1 - 8.7e-22 78.4 0.0 1.6e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) OxoGdeHyase_C PF16870.5 RUS88917.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal Claudin_2 PF13903.6 RUS88918.1 - 5.3e-12 45.9 10.7 1.8e-10 40.9 10.7 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 RUS88918.1 - 3.9e-06 27.2 0.1 3.9e-06 27.2 0.1 2.3 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 RUS88918.1 - 0.015 15.2 12.6 0.14 12.0 12.5 2.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DuoxA PF10204.9 RUS88918.1 - 0.041 12.9 13.1 0.2 10.7 7.7 2.4 2 1 0 2 2 2 0 Dual oxidase maturation factor EI24 PF07264.11 RUS88918.1 - 0.1 12.8 5.2 2.4 8.4 5.2 2.2 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PorA PF11271.8 RUS88918.1 - 0.2 10.9 0.6 0.75 9.0 0.0 2.0 2 0 0 2 2 2 0 Porin PorA DctQ PF04290.12 RUS88918.1 - 0.52 10.2 7.9 0.19 11.7 3.8 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Neurensin PF14927.6 RUS88918.1 - 0.62 9.8 0.0 0.62 9.8 0.0 2.7 3 1 0 3 3 3 0 Neurensin Clc-like PF07062.12 RUS88918.1 - 0.97 8.9 6.0 0.16 11.4 1.4 2.3 1 1 0 2 2 2 0 Clc-like PIG-Y PF15159.6 RUS88918.1 - 1.3 10.0 0.1 1.3 10.0 0.1 2.6 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2627 PF11118.8 RUS88918.1 - 3.6 8.2 7.2 3.8 8.1 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF2207 PF09972.9 RUS88918.1 - 9 4.9 8.9 4.3 6.0 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CAP_N PF01213.19 RUS88919.1 - 4.1e-100 335.3 0.0 4.1e-100 335.3 0.0 3.4 2 1 1 3 3 3 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 RUS88919.1 - 1.5e-65 219.6 3.9 1.5e-65 219.6 3.9 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 RUS88919.1 - 0.0062 16.3 4.2 0.035 13.9 3.2 2.2 1 1 1 2 2 2 2 Tubulin binding cofactor C AKNA PF12443.8 RUS88919.1 - 0.037 14.7 0.5 0.25 12.0 0.0 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor YL1 PF05764.13 RUS88921.1 - 0.0012 19.1 5.5 0.0013 18.9 5.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Sporozoite_P67 PF05642.11 RUS88921.1 - 0.008 14.3 0.5 0.0074 14.4 0.5 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SDA1 PF05285.12 RUS88921.1 - 0.0087 15.5 3.9 0.011 15.1 3.9 1.2 1 1 0 1 1 1 1 SDA1 FAM176 PF14851.6 RUS88921.1 - 0.015 15.0 0.7 0.021 14.5 0.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 RUS88921.1 - 0.096 12.9 6.4 0.18 12.1 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3245 PF11595.8 RUS88921.1 - 0.27 11.7 4.7 0.5 10.8 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) E7 PF00527.18 RUS88921.1 - 0.29 11.4 1.2 20 5.5 1.9 2.2 2 0 0 2 2 2 0 E7 protein, Early protein NOA36 PF06524.12 RUS88921.1 - 0.52 9.6 14.9 0.68 9.2 14.9 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 RUS88921.1 - 0.73 8.0 9.8 0.95 7.7 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS88921.1 - 1.1 7.3 9.9 1.6 6.8 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 RUS88921.1 - 3.2 7.4 13.3 4.2 7.0 13.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 RUS88921.1 - 3.3 8.1 14.8 6.3 7.2 14.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 RUS88921.1 - 4 7.4 9.3 1.8 8.6 6.8 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RUS88921.1 - 4.2 5.4 21.1 3.7 5.5 19.9 1.5 1 1 1 2 2 2 0 DNA polymerase phi RRM_1 PF00076.22 RUS88922.1 - 9.3e-19 67.0 0.0 1.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS88922.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS88922.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sulf_coat_C PF12193.8 RUS88923.1 - 0.037 14.1 0.4 33 4.6 0.0 4.1 4 0 0 4 4 4 0 Sulfolobus virus coat protein C terminal MmgE_PrpD PF03972.14 RUS88923.1 - 0.045 12.3 0.6 2.2 6.7 0.1 2.5 1 1 2 3 3 3 0 MmgE/PrpD family HSP70 PF00012.20 RUS88926.1 - 7.1e-179 595.8 0.0 8.9e-179 595.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RUS88926.1 - 7.2e-11 41.5 0.5 2.3e-10 39.8 0.0 2.0 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 RUS88926.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 RUS88926.1 - 0.021 14.3 0.0 6.5 6.2 0.0 3.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family cwf21 PF08312.12 RUS88926.1 - 0.028 14.6 0.2 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 cwf21 domain Ribosomal_S14 PF00253.21 RUS88927.1 - 1.3e-17 63.3 0.4 2.8e-17 62.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RecR PF02132.15 RUS88928.1 - 0.092 12.3 1.1 0.092 12.3 1.1 2.3 2 0 0 2 2 2 0 RecR protein PolC_DP2 PF03833.13 RUS88928.1 - 0.84 7.4 2.9 0.99 7.2 2.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.6 RUS88928.1 - 4.6 7.2 11.1 1.2e+02 2.6 11.1 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Hydrolase_4 PF12146.8 RUS88929.1 - 7.6e-18 64.6 0.0 3.1e-10 39.7 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS88929.1 - 1.2e-13 51.3 0.1 1.1e-06 28.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS88929.1 - 3.7e-07 31.0 0.0 5.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 RUS88929.1 - 7.6e-07 28.1 0.1 0.023 13.4 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 RUS88929.1 - 4.1e-05 23.5 0.1 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 RUS88929.1 - 9.5e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 RUS88929.1 - 0.00017 21.5 0.0 0.0044 17.0 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 RUS88929.1 - 0.00019 21.4 0.1 0.00038 20.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 RUS88929.1 - 0.00031 20.3 0.0 0.007 15.9 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 RUS88929.1 - 0.0019 17.9 0.0 1.2 8.7 0.0 2.3 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 RUS88929.1 - 0.002 17.9 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 RUS88929.1 - 0.0047 15.9 0.1 0.28 10.1 0.0 2.2 1 1 1 2 2 2 1 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 RUS88929.1 - 0.0049 16.6 0.0 0.051 13.3 0.0 2.2 2 1 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.25 RUS88929.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) F-box PF00646.33 RUS88929.1 - 0.092 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box domain DUF2974 PF11187.8 RUS88929.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 RUS88929.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 RUS88929.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ribophorin_II PF05817.14 RUS88930.1 - 7.2e-23 81.0 0.2 9.3e-23 80.6 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II SET_assoc PF11767.8 RUS88930.1 - 0.073 12.7 0.0 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Vitellogenin_N PF01347.22 RUS88930.1 - 0.15 10.4 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region ApeC PF16977.5 RUS88931.1 - 2.2e-32 112.7 0.8 3.1e-32 112.2 0.8 1.2 1 0 0 1 1 1 1 C-terminal domain of apextrin DUF3662 PF12401.8 RUS88931.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) PKD PF00801.20 RUS88932.1 - 2.3e-24 85.0 42.9 1.2e-08 34.7 1.2 8.7 8 0 0 8 8 8 5 PKD domain WSC PF01822.19 RUS88932.1 - 8.3e-16 57.9 2.0 8.3e-16 57.9 2.0 3.1 3 0 0 3 3 3 1 WSC domain CBM_35 PF16990.5 RUS88932.1 - 0.052 13.8 0.5 5.5 7.3 0.2 3.5 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) Y_Y_Y PF07495.13 RUS88932.1 - 0.062 13.3 1.4 0.34 10.9 0.8 2.5 2 0 0 2 2 2 0 Y_Y_Y domain REJ PF02010.15 RUS88933.1 - 2.8e-13 49.5 0.2 4.5e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 REJ domain PKD PF00801.20 RUS88933.1 - 7.4e-05 22.5 2.1 0.041 13.7 0.1 3.0 3 0 0 3 3 3 2 PKD domain Y_Y_Y PF07495.13 RUS88933.1 - 0.00084 19.2 0.6 0.41 10.6 0.1 2.7 2 0 0 2 2 2 2 Y_Y_Y domain ChitinaseA_N PF08329.10 RUS88933.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Chitinase A, N-terminal domain CBFB_NFYA PF02045.15 RUS88934.1 - 2.6 8.7 5.4 12 6.6 0.5 2.8 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B POT1 PF02765.17 RUS88935.1 - 8.9e-28 96.9 0.8 3.1e-27 95.2 0.0 2.4 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 RUS88935.1 - 1.1e-24 87.1 0.0 8.1e-24 84.3 0.0 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein Ras PF00071.22 RUS88936.1 - 2.4e-13 50.0 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS88936.1 - 6.1e-08 32.9 0.0 9.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 RUS88936.1 - 0.0045 17.0 0.8 0.11 12.6 1.5 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 RUS88936.1 - 0.058 13.1 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 RUS88936.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.23 RUS88936.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RUS88936.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ParA PF10609.9 RUS88936.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 RUS88936.1 - 0.19 11.3 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 RUS88936.1 - 0.2 12.2 0.0 0.32 11.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter ArsA_ATPase PF02374.15 RUS88936.1 - 0.21 10.7 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase IIGP PF05049.13 RUS88936.1 - 0.25 10.4 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Lectin_C PF00059.21 RUS88937.1 - 3.8e-12 46.9 0.7 1e-11 45.5 0.7 1.8 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS88937.1 - 3.4e-07 30.1 1.8 1e-06 28.6 1.8 1.9 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 RUS88937.1 - 0.0045 16.9 2.0 0.012 15.5 0.7 2.5 2 0 0 2 2 2 1 PAN domain Lectin_C PF00059.21 RUS88938.1 - 1.9e-10 41.4 0.9 1.9e-10 41.4 0.9 2.4 2 2 0 2 2 2 1 Lectin C-type domain PAN_1 PF00024.26 RUS88938.1 - 1.1e-07 31.7 1.7 1.1e-07 31.7 1.7 1.9 2 0 0 2 2 2 1 PAN domain HMMR_C PF15908.5 RUS88939.1 - 0.016 15.5 5.9 0.039 14.2 5.9 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal EzrA PF06160.12 RUS88939.1 - 0.069 11.3 10.8 2.4 6.2 10.8 2.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CCDC144C PF14915.6 RUS88939.1 - 0.2 10.8 23.1 0.029 13.5 10.8 2.7 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region YabA PF06156.13 RUS88939.1 - 0.49 11.1 16.0 0.14 12.8 1.9 3.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF948 PF06103.11 RUS88939.1 - 3.1 8.1 4.7 26 5.1 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CH PF00307.31 RUS88940.1 - 5.2e-21 74.9 0.1 3.6e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain Kelch_1 PF01344.25 RUS88941.1 - 9.3e-83 271.6 22.9 1.9e-16 59.3 0.9 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 RUS88941.1 - 3.1e-34 117.2 1.0 3.1e-34 117.2 1.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS88941.1 - 5.9e-33 112.1 3.7 4.8e-07 29.8 0.1 6.5 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 RUS88941.1 - 1.8e-31 108.7 0.7 3.5e-31 107.7 0.7 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RUS88941.1 - 6.6e-23 79.8 10.6 2e-05 24.4 0.3 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RUS88941.1 - 7.3e-20 70.8 11.6 3.2e-07 30.5 0.3 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS88941.1 - 1.9e-17 63.0 2.5 5.1e-06 26.4 0.1 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS88941.1 - 0.00012 22.0 17.2 0.13 12.2 0.1 5.3 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 RUS88941.1 - 0.0014 19.1 16.4 0.59 10.7 0.0 5.3 5 0 0 5 5 5 2 PQQ-like domain DUF3342 PF11822.8 RUS88941.1 - 0.0063 16.7 0.7 0.061 13.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) S_layer_N PF05123.12 RUS88941.1 - 0.046 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region IQ PF00612.27 RUS88942.1 - 1.8e-06 27.3 0.0 4.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 RUS88942.1 - 0.00016 21.3 2.2 0.096 12.4 0.5 2.8 2 0 0 2 2 2 2 Dpy-30 motif Oxidored-like PF09791.9 RUS88943.1 - 8.1e-12 44.6 1.7 1.4e-11 43.9 1.7 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ATPase-cat_bd PF12156.8 RUS88943.1 - 0.0083 16.8 1.6 0.012 16.3 0.6 1.8 1 1 1 2 2 2 1 Putative metal-binding domain of cation transport ATPase ALMT PF11744.8 RUS88943.1 - 2.9 6.6 7.3 3.4 6.4 7.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PNKP-ligase_C PF16536.5 RUS88944.1 - 0.82 10.0 2.7 8.3 6.7 0.1 2.7 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Linker_histone PF00538.19 RUS88945.1 - 2.6e-12 46.9 0.1 2.6e-12 46.9 0.1 2.7 3 1 0 3 3 3 1 linker histone H1 and H5 family Zip PF02535.22 RUS88945.1 - 3.3 6.8 6.1 11 5.2 6.1 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 RUS88945.1 - 4.7 4.2 16.2 6 3.8 16.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DEAD PF00270.29 RUS88950.1 - 2.7e-50 170.6 0.0 6e-49 166.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS88950.1 - 7.5e-31 106.8 0.0 6.3e-30 103.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS88950.1 - 8.8e-06 25.8 0.0 5e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RUS88950.1 - 0.045 12.5 1.2 0.94 8.2 0.0 2.4 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 cobW PF02492.19 RUS88950.1 - 0.092 12.3 0.5 0.32 10.6 0.7 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UQ_con PF00179.26 RUS88951.1 - 2.6e-25 88.7 0.0 5.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DDDD PF10161.9 RUS88952.1 - 5.1e-25 87.0 0.0 6.3e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Putative mitochondrial precursor protein FOP_dimer PF09398.10 RUS88953.1 - 3.4e-16 59.3 0.1 8.2e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Mito_carr PF00153.27 RUS88954.1 - 3.5e-49 164.7 1.5 7.7e-18 64.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein LRRC37 PF15779.5 RUS88954.1 - 0.46 10.9 1.7 8.4 6.8 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeat-containing protein 37 family Ank_4 PF13637.6 RUS88956.1 - 7e-09 36.1 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS88956.1 - 0.0017 18.9 0.0 0.0034 17.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS88956.1 - 0.0026 18.1 0.0 0.59 10.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RUS88956.1 - 0.0031 17.8 0.1 0.058 13.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PPP4R2 PF09184.11 RUS88959.1 - 0.67 9.5 4.7 0.81 9.2 4.7 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS88960.1 - 0.0081 15.5 21.2 0.0081 15.5 21.2 2.1 2 0 0 2 2 2 1 NOA36 protein HAS-barrel PF09378.10 RUS88960.1 - 0.8 9.9 3.1 2.9 8.1 0.8 2.6 2 0 0 2 2 2 0 HAS barrel domain PPP4R2 PF09184.11 RUS88960.1 - 3.1 7.3 23.0 0.048 13.2 13.6 2.0 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 RUS88960.1 - 6.8 4.8 17.1 0.11 10.8 9.4 1.7 2 0 0 2 2 2 0 CDC45-like protein EGF_3 PF12947.7 RUS88961.1 - 0.014 15.6 0.6 0.014 15.6 0.6 2.1 2 0 0 2 2 2 0 EGF domain EGF_CA PF07645.15 RUS88961.1 - 0.049 13.8 4.7 0.049 13.8 4.7 2.9 2 1 0 2 2 2 0 Calcium-binding EGF domain D_CNTX PF17492.2 RUS88961.1 - 0.099 12.8 5.7 2.1 8.6 0.5 2.3 2 0 0 2 2 2 0 Delta Ctenitoxins 7tm_3 PF00003.22 RUS88962.1 - 7.9e-25 88.0 8.0 9.4e-25 87.7 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EpsG PF14897.6 RUS88962.1 - 0.0014 18.0 1.1 0.002 17.5 1.1 1.2 1 0 0 1 1 1 1 EpsG family 7tm_3 PF00003.22 RUS88963.1 - 5.5e-17 62.3 2.4 5.8e-17 62.2 2.4 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4674 PF15719.5 RUS88965.1 - 8.6e-07 29.2 30.9 9.1e-06 25.8 19.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4674) zf_C2H2_13 PF18508.1 RUS88965.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Zinc finger domain Yippee-Mis18 PF03226.14 RUS88965.1 - 0.051 13.8 1.4 0.092 13.0 1.4 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrom_NNT PF03264.14 RUS88965.1 - 0.13 11.9 3.2 0.078 12.7 1.4 1.5 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF3461 PF11944.8 RUS88965.1 - 0.24 11.6 5.4 13 5.9 5.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) NAD_binding_6 PF08030.12 RUS88967.1 - 6e-30 104.4 0.0 8.7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RUS88967.1 - 1.2e-22 80.1 0.0 2.1e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 RUS88967.1 - 0.0037 17.6 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 RUS88967.1 - 0.16 12.6 0.0 0.65 10.7 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain LSM PF01423.22 RUS88968.1 - 9.1e-11 41.3 0.3 1.4e-10 40.7 0.3 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RUS88968.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Insulin PF00049.18 RUS88969.1 - 6.6e-08 33.5 4.9 1.9e-07 31.9 4.9 1.7 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Jas PF16135.5 RUS88969.1 - 0.049 13.8 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling ALF PF03752.13 RUS88969.1 - 0.099 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Short repeats of unknown function Ins_beta PF03488.14 RUS88969.1 - 0.59 10.2 6.7 2.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type tRNA-synt_1b PF00579.25 RUS88970.1 - 5.1e-46 157.3 0.0 5.7e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DNA_pol_phi PF04931.13 RUS88971.1 - 0.0058 14.8 35.4 0.0074 14.4 35.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 RUS88971.1 - 0.021 14.2 11.4 0.025 13.9 11.4 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 RUS88971.1 - 0.12 12.1 5.6 0.17 11.6 5.6 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Mpp10 PF04006.12 RUS88971.1 - 0.15 10.5 13.9 0.18 10.2 13.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 RUS88971.1 - 0.21 9.8 22.1 0.26 9.4 22.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 RUS88971.1 - 0.32 10.7 3.9 0.46 10.2 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 RUS88971.1 - 0.36 10.2 13.6 0.49 9.7 13.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd2 PF05786.14 RUS88971.1 - 0.45 9.1 13.1 0.5 9.0 13.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SAPS PF04499.15 RUS88971.1 - 0.65 8.7 2.6 0.83 8.4 2.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IFT57 PF10498.9 RUS88971.1 - 0.66 8.9 5.3 0.82 8.6 5.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sigma70_ner PF04546.13 RUS88971.1 - 0.74 9.7 15.8 1.3 8.9 15.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2722 PF10846.8 RUS88971.1 - 1.2 7.9 11.9 1.6 7.6 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FYDLN_acid PF09538.10 RUS88971.1 - 1.3 9.7 28.9 2.9 8.6 28.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CNDH2_C PF16858.5 RUS88971.1 - 1.4 8.8 6.8 1.7 8.4 6.8 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 RUS88971.1 - 1.7 8.0 22.4 2.2 7.6 22.4 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 RUS88971.1 - 7.9 5.5 42.7 15 4.6 42.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ion_trans_2 PF07885.16 RUS88972.1 - 7.8e-11 41.8 0.6 2e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 RUS88972.1 - 2.2e-08 34.2 0.0 6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Apq12 PF12716.7 RUS88972.1 - 0.04 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Ion_trans PF00520.31 RUS88972.1 - 0.063 12.5 0.2 0.17 11.1 0.2 1.6 1 0 0 1 1 1 0 Ion transport protein Lectin_C PF00059.21 RUS88973.1 - 2.3e-07 31.5 2.5 4.1e-07 30.7 1.0 2.0 1 1 1 2 2 2 1 Lectin C-type domain UL45 PF05473.12 RUS88973.1 - 0.00025 20.7 0.2 0.00084 19.0 0.1 2.0 1 1 1 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like tRNA_int_endo PF01974.17 RUS88974.1 - 2.2e-20 72.5 0.0 4.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PRP1_N PF06424.12 RUS88975.1 - 2.7e-55 186.8 7.0 2.7e-55 186.8 7.0 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 RUS88975.1 - 5.4e-30 101.5 32.2 0.0021 18.7 0.0 14.5 6 4 9 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 RUS88975.1 - 9.9e-22 77.2 11.3 3.2e-07 30.8 0.1 8.8 7 3 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 RUS88975.1 - 2.8e-13 49.2 0.2 0.068 13.6 0.0 8.3 12 0 0 12 12 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS88975.1 - 8.8e-13 47.3 3.3 0.015 15.3 0.0 9.5 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 RUS88975.1 - 5.3e-11 43.0 12.5 0.0014 19.2 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS88975.1 - 1.1e-08 34.6 0.6 0.47 10.8 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat Suf PF05843.14 RUS88975.1 - 1.6e-05 25.1 2.6 0.14 12.1 0.0 5.4 5 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_9 PF13371.6 RUS88975.1 - 2.2e-05 24.5 2.2 0.036 14.2 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS88975.1 - 4.8e-05 23.7 2.6 27 5.7 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 RUS88975.1 - 0.00059 19.6 5.9 0.2 11.4 0.5 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain ChAPs PF09295.10 RUS88975.1 - 0.0026 16.8 4.2 0.06 12.3 0.1 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 RUS88975.1 - 0.0045 16.7 0.3 7.5 6.6 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RUS88975.1 - 0.0062 16.2 0.1 16 5.3 0.0 5.3 4 1 2 6 6 6 0 TPR repeat OsmC PF02566.19 RUS88975.1 - 0.028 14.9 0.5 13 6.3 0.0 4.2 4 0 0 4 4 4 0 OsmC-like protein Babuvirus_MP PF07234.11 RUS88975.1 - 0.051 13.7 0.1 17 5.6 0.0 4.0 3 1 1 4 4 4 0 Movement and RNA silencing protein ZNRF_3_ecto PF18212.1 RUS88975.1 - 0.087 12.8 0.0 3.1 7.8 0.0 3.4 3 1 1 4 4 3 0 ZNRF-3 Ectodomain MREG PF15812.5 RUS88975.1 - 0.12 12.7 2.1 0.46 10.8 2.1 2.0 1 0 0 1 1 1 0 Melanoregulin EMP70 PF02990.16 RUS88977.1 - 1.5e-155 518.9 10.8 2e-155 518.4 10.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 YjgF_endoribonc PF14588.6 RUS88980.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Homeodomain PF00046.29 RUS88981.1 - 7.6e-14 51.3 7.9 2.1e-08 33.9 0.8 2.5 2 0 0 2 2 2 2 Homeodomain Ferritin PF00210.24 RUS88981.1 - 0.039 13.9 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Ferritin-like domain UvrD-helicase PF00580.21 RUS88981.1 - 0.19 11.2 0.1 0.31 10.5 0.0 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Bombolitin PF08096.11 RUS88983.1 - 0.0016 18.6 0.6 9.7 6.7 0.0 3.8 4 0 0 4 4 4 2 Bombolitin family RVT_thumb PF06817.14 RUS88983.1 - 0.0053 16.6 1.1 3.9 7.4 0.1 2.8 1 1 2 3 3 3 2 Reverse transcriptase thumb domain RNA_pol_Rpb2_7 PF04560.20 RUS88983.1 - 0.0056 17.1 4.6 0.38 11.2 1.4 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 7 PuR_N PF09182.10 RUS88983.1 - 0.027 14.4 2.3 0.04 13.8 0.7 1.9 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal TMEM132 PF16070.5 RUS88983.1 - 0.029 13.7 3.6 1 8.6 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein family 132 NARG2_C PF10505.9 RUS88983.1 - 0.061 12.8 3.8 0.09 12.3 3.5 1.4 1 1 1 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus BRCA2 PF00634.18 RUS88983.1 - 0.42 10.3 11.8 14 5.5 0.2 4.7 3 2 2 5 5 5 0 BRCA2 repeat Robl_LC7 PF03259.17 RUS88984.1 - 1.9e-10 40.4 0.0 2.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain PTPLA PF04387.14 RUS88985.1 - 3.1e-61 205.9 14.8 1.3e-60 203.8 12.2 2.0 2 0 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA LNS2 PF08235.13 RUS88986.1 - 4.2e-98 327.3 0.0 8.1e-98 326.4 0.0 1.5 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 RUS88986.1 - 8.7e-44 147.7 0.0 1.8e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 RUS88986.1 - 3.2e-30 104.2 0.1 3.2e-30 104.2 0.1 2.0 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 RUS88986.1 - 0.017 16.0 4.4 0.038 14.9 0.0 3.5 3 1 0 3 3 3 0 Putative WW-binding domain and destruction box DUF692 PF05114.13 RUS88986.1 - 0.066 12.4 0.0 0.066 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF692) Lactamase_B PF00753.27 RUS88990.1 - 9.7e-22 77.9 6.8 2.1e-21 76.8 6.8 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS88990.1 - 0.0012 18.5 0.8 0.0021 17.6 0.8 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS88990.1 - 0.031 14.2 0.1 0.066 13.1 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TMEM154 PF15102.6 RUS88991.1 - 0.42 10.5 0.0 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family DHHC PF01529.20 RUS88991.1 - 0.44 10.7 12.2 1.6 8.9 9.1 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF5090 PF17009.5 RUS88991.1 - 3.1 7.7 8.0 11 6.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Far-17a_AIG1 PF04750.14 RUS88992.1 - 4.3e-53 179.7 19.4 4.9e-53 179.5 19.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein EAV_GS PF01309.18 RUS88992.1 - 0.028 14.0 1.0 0.056 13.1 1.0 1.5 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein TMEM239 PF15841.5 RUS88992.1 - 1.3 8.9 5.8 0.31 10.9 0.8 2.1 2 0 0 2 2 2 0 Transmembrane protein 239 family Far-17a_AIG1 PF04750.14 RUS88993.1 - 2.5e-48 164.1 18.8 2.9e-48 163.9 18.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein TMF_DNA_bd PF12329.8 RUS88994.1 - 7.1e-15 54.8 20.3 7.1e-15 54.8 20.3 7.0 5 2 2 7 7 7 3 TATA element modulatory factor 1 DNA binding Fringe PF02434.16 RUS88995.1 - 1.4e-103 345.8 0.0 1.7e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 RUS88995.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.6 RUS88995.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 SNARE PF05739.19 RUS88996.1 - 7.3e-06 25.9 3.0 2.4e-05 24.2 3.0 2.0 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 RUS88996.1 - 0.00023 20.6 5.0 0.00042 19.8 5.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Telomere_reg-2 PF10193.9 RUS88996.1 - 0.014 15.8 0.4 0.014 15.8 0.4 1.9 2 1 0 2 2 2 0 Telomere length regulation protein DUF745 PF05335.13 RUS88996.1 - 0.038 13.7 9.9 0.42 10.3 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) WXG100 PF06013.12 RUS88996.1 - 0.16 12.2 3.2 2 8.7 0.3 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF3675 PF12428.8 RUS88996.1 - 0.19 12.3 0.2 0.19 12.3 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3675) HrpB7 PF09486.10 RUS88996.1 - 0.26 11.6 11.9 0.25 11.7 2.6 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Herpes_US9 PF06072.11 RUS88996.1 - 0.28 11.1 5.6 0.38 10.7 3.6 2.3 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Use1 PF09753.9 RUS88996.1 - 0.51 10.0 10.5 1.8 8.2 10.5 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 XhlA PF10779.9 RUS88996.1 - 0.54 10.5 4.7 16 5.8 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA IFT57 PF10498.9 RUS88996.1 - 0.84 8.5 9.1 0.066 12.2 1.9 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 RUS88996.1 - 0.96 8.3 13.0 0.21 10.4 3.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 RUS88996.1 - 1 9.7 10.2 0.17 12.2 4.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 RUS88996.1 - 1.3 9.1 8.2 5.3 7.1 0.9 2.4 2 1 0 2 2 2 0 Laminin Domain II SlyX PF04102.12 RUS88996.1 - 9.4 6.9 15.2 14 6.4 1.0 3.7 2 2 2 4 4 4 0 SlyX FliD_C PF07195.12 RUS88996.1 - 9.5 5.6 11.2 2.1 7.7 4.3 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Laminin_N PF00055.17 RUS88997.1 - 2.4e-78 263.0 1.4 2.4e-78 263.0 1.4 3.0 3 1 0 3 3 3 1 Laminin N-terminal (Domain VI) NTR PF01759.21 RUS88997.1 - 6.7e-24 83.8 0.1 1.5e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 RUS88997.1 - 1.1e-19 70.3 73.2 3.1e-09 36.8 12.2 5.1 6 0 0 6 6 6 3 Laminin EGF domain BNR_6 PF15899.5 RUS88997.1 - 0.034 14.2 0.3 0.1 12.7 0.3 1.8 1 0 0 1 1 1 0 BNR-Asp box repeat Pas_Saposin PF09016.10 RUS88998.1 - 1.6e-06 28.4 1.4 86 3.6 0.0 8.5 1 1 6 9 9 9 0 Pas factor saposin fold Tsi6 PF18660.1 RUS88998.1 - 0.001 19.1 11.5 3.4 7.8 0.2 6.8 1 1 6 7 7 7 1 Tsi6 DUF4713 PF15831.5 RUS88998.1 - 0.0016 18.9 9.6 1.1e+02 3.4 0.0 8.0 2 2 8 13 13 13 0 Domain of unknown function (DUF4713) Chlam_OMP PF01308.17 RUS88998.1 - 0.0022 16.9 23.1 0.19 10.5 2.5 3.8 1 1 3 4 4 4 4 Chlamydia major outer membrane protein Invas_SpaK PF03519.14 RUS88998.1 - 0.037 14.1 1.8 72 3.5 0.0 5.2 1 1 1 4 4 4 0 Invasion protein B family FadA PF09403.10 RUS88998.1 - 0.05 14.1 9.6 6.4 7.3 0.5 4.8 1 1 4 5 5 5 0 Adhesion protein FadA Exotox-A_cataly PF09009.10 RUS88998.1 - 0.056 13.2 5.9 8.3 6.1 0.2 3.7 1 1 5 6 6 6 0 Exotoxin A catalytic IpaB_EvcA PF03278.13 RUS88998.1 - 0.15 11.8 3.2 5.2 6.8 0.3 3.2 1 1 1 3 3 3 0 IpaB/EvcA family DUF1843 PF08898.10 RUS88998.1 - 0.21 12.1 16.8 40 4.8 0.1 6.6 1 1 6 9 9 9 0 Domain of unknown function (DUF1843) RBD PF02196.15 RUS88998.1 - 0.9 9.7 17.7 3.1 7.9 0.5 4.7 1 1 2 4 4 4 0 Raf-like Ras-binding domain Pathogen_betaC1 PF09593.10 RUS88998.1 - 1.5 8.7 10.4 19 5.2 0.2 4.6 2 2 2 4 4 4 0 Beta-satellite pathogenicity beta C1 protein Cu_bind_CorA PF18252.1 RUS88998.1 - 3.8 7.1 17.6 8.1 6.0 0.6 4.6 1 1 3 5 5 5 0 Copper(I)-binding protein CorA 2H-phosphodiest PF08975.10 RUS88998.1 - 5.5 7.0 14.7 6.9 6.7 0.9 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1868) DHR10 PF18595.1 RUS88999.1 - 4.7 7.3 5.6 37 4.4 0.2 2.9 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain DUF3642 PF12182.8 RUS88999.1 - 6.5 7.1 5.9 99 3.3 0.2 3.6 1 1 3 4 4 4 0 Bacterial lipoprotein Myosin_tail_1 PF01576.19 RUS89001.1 - 0 1290.3 318.3 0 1290.0 318.3 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 RUS89001.1 - 2.2e-302 1004.4 3.2 2.2e-302 1004.4 3.2 2.8 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.19 RUS89001.1 - 6.6e-09 35.5 0.6 1.9e-08 34.0 0.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 RUS89001.1 - 0.017 14.9 0.6 0.048 13.5 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 RUS89001.1 - 0.084 13.1 0.0 0.084 13.1 0.0 5.8 4 2 2 7 7 7 0 AAA domain zf-HC5HC2H PF13771.6 RUS89003.1 - 5.9e-11 42.5 10.6 5.9e-11 42.5 10.6 2.6 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RUS89003.1 - 1.3e-09 38.2 6.3 1.3e-09 38.2 6.3 2.6 3 0 0 3 3 3 1 PHD-zinc-finger like domain MMR_HSR1_Xtn PF16897.5 RUS89004.1 - 2.4e-42 143.3 0.0 5e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 RUS89004.1 - 6.7e-23 80.5 0.0 1.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 RUS89004.1 - 3.7e-22 78.5 0.0 8.1e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS89004.1 - 5.6e-12 45.4 0.0 9.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RUS89004.1 - 0.00014 21.9 0.3 0.75 9.8 0.1 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 RUS89004.1 - 0.021 14.7 0.6 0.088 12.7 0.1 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 RUS89004.1 - 0.027 14.7 0.1 0.095 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 RUS89004.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 RUS89004.1 - 0.03 13.7 0.3 0.16 11.4 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 RUS89004.1 - 0.034 14.4 0.1 0.081 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RUS89004.1 - 0.035 14.5 0.0 0.086 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 RUS89004.1 - 0.037 13.0 0.4 0.21 10.5 0.1 2.4 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RUS89004.1 - 0.1 13.1 0.1 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Aconitase PF00330.20 RUS89005.1 - 1.3e-149 499.2 0.0 1.6e-149 498.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RUS89005.1 - 4.1e-46 156.5 0.1 1.5e-45 154.7 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain IBR PF01485.21 RUS89007.1 - 1.6e-12 47.5 37.9 3.1e-07 30.5 5.3 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 RUS89007.1 - 0.0067 16.4 7.9 0.0067 16.4 7.9 3.6 4 0 0 4 4 4 1 zinc-RING finger domain Utp13 PF08625.11 RUS89007.1 - 0.013 15.4 0.7 0.045 13.7 0.1 2.1 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain IBR PF01485.21 RUS89008.1 - 4.6e-12 46.0 20.5 3e-07 30.6 7.3 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Atthog PF18800.1 RUS89009.1 - 3.9e-69 231.0 9.6 4.9e-69 230.7 9.6 1.1 1 0 0 1 1 1 1 Attenuator of Hedgehog L_HMGIC_fpl PF10242.9 RUS89009.1 - 1.1e-05 25.7 10.6 1.7e-05 25.1 10.6 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.11 RUS89009.1 - 0.034 14.1 13.9 0.06 13.3 13.9 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF2070 PF09843.9 RUS89009.1 - 0.57 8.4 8.2 0.6 8.3 8.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF202 PF02656.15 RUS89009.1 - 1.3 9.5 11.6 2.5 8.6 2.9 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2975 PF11188.8 RUS89009.1 - 1.4 8.9 15.0 0.8 9.6 10.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Phage_holin_1 PF04531.13 RUS89009.1 - 2.8 8.6 5.0 0.43 11.1 0.2 2.2 3 1 0 3 3 3 0 Bacteriophage holin DUF3671 PF12420.8 RUS89009.1 - 6.2 6.9 11.4 0.91 9.6 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function CENP-C_C PF11699.8 RUS89010.1 - 5.3e-07 29.7 4.7 3.2 8.0 0.0 7.2 3 2 5 8 8 8 2 Mif2/CENP-C like ID PF18543.1 RUS89010.1 - 0.32 11.1 48.5 7.3 6.7 0.4 11.9 3 3 12 15 15 15 0 Intracellular delivery domain YqbF PF14553.6 RUS89010.1 - 0.73 9.7 9.0 9 6.3 0.0 6.1 6 1 0 7 7 7 0 YqbF, hypothetical protein domain DUF4062 PF13271.6 RUS89011.1 - 4.9e-13 49.2 0.0 1.3e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) DUF3915 PF13054.6 RUS89011.1 - 0.91 9.5 12.4 1.7 8.6 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS89011.1 - 1.3 7.2 20.0 1.8 6.7 20.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family AAA_16 PF13191.6 RUS89012.1 - 2.2e-05 24.9 0.0 7.3e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS89012.1 - 0.0001 22.6 0.0 0.00051 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS89012.1 - 0.0019 18.1 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain APAF1_C PF17908.1 RUS89012.1 - 0.0046 17.0 0.1 0.015 15.3 0.1 1.9 1 0 0 1 1 1 1 APAF-1 helical domain SRP14 PF02290.15 RUS89012.1 - 0.029 14.7 1.2 5.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Mating_N PF12731.7 RUS89012.1 - 0.033 14.3 0.3 13 5.9 0.0 3.0 2 0 0 2 2 2 0 Mating-type protein beta 1 ANAPC4_WD40 PF12894.7 RUS89014.1 - 1.9e-08 34.5 0.1 0.0027 17.9 0.0 5.2 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS89014.1 - 6.2e-08 33.2 2.6 0.23 12.4 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 RUS89014.1 - 7.7e-05 21.5 11.6 0.12 11.0 1.5 4.3 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Hira PF07569.11 RUS89014.1 - 0.048 13.4 6.6 4.7 6.9 0.1 4.1 4 1 1 5 5 5 0 TUP1-like enhancer of split SAM_1 PF00536.30 RUS89015.1 - 7.4e-10 39.1 0.0 1.8e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS89015.1 - 0.00057 19.9 0.1 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 RUS89015.1 - 0.00083 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 RUS89015.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif HTH_17 PF12728.7 RUS89015.1 - 0.039 14.1 0.2 46 4.3 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Cation_ATPase_C PF00689.21 RUS89017.1 - 4.2e-41 140.7 10.2 9.5e-41 139.5 7.2 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RUS89017.1 - 6.4e-36 123.6 13.2 2.9e-26 92.1 0.4 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 RUS89017.1 - 2e-19 69.4 0.1 4.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ATP_Ca_trans_C PF12424.8 RUS89017.1 - 1e-14 54.7 1.7 1e-14 54.7 1.7 2.3 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.26 RUS89017.1 - 1e-14 55.4 0.2 4.2e-14 53.3 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RUS89017.1 - 9.4e-07 28.8 3.7 0.00015 21.6 0.1 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF1387 PF07139.11 RUS89017.1 - 5.1 6.7 11.8 8.8 6.0 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Cation_ATPase_N PF00690.26 RUS89019.1 - 2.3e-15 56.1 0.0 2.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus SNF PF00209.18 RUS89020.1 - 7.9e-163 542.9 27.1 9.7e-163 542.6 27.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ank_2 PF12796.7 RUS89022.1 - 3.8e-34 117.1 2.1 2.4e-18 66.5 0.4 3.3 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS89022.1 - 9.6e-29 99.4 7.0 3.6e-08 33.8 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS89022.1 - 1.9e-27 94.4 3.2 3.2e-08 33.7 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS89022.1 - 9.9e-24 83.1 4.8 3.5e-09 36.7 0.3 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89022.1 - 2.5e-21 73.5 5.2 0.0022 18.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.16 RUS89022.1 - 5e-09 36.4 3.2 1.1e-08 35.3 3.2 1.5 1 0 0 1 1 1 1 SOCS box DUF1110 PF06533.12 RUS89022.1 - 0.1 12.5 0.3 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) MitoNEET_N PF10660.9 RUS89022.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Sulfotransfer_2 PF03567.14 RUS89024.1 - 1.5e-26 93.9 0.4 1.5e-21 77.4 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family DTC PF18102.1 RUS89025.1 - 6.6e-26 91.0 0.0 8.3e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Deltex C-terminal domain DTC PF18102.1 RUS89027.1 - 3.5e-51 172.8 0.1 1.7e-50 170.6 0.1 2.1 2 0 0 2 2 2 1 Deltex C-terminal domain Macro PF01661.21 RUS89027.1 - 5.8e-29 100.5 0.1 1.3e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Macro domain zf-C3HC4_3 PF13920.6 RUS89027.1 - 0.00023 20.9 10.3 0.00023 20.9 10.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS89027.1 - 0.13 12.2 10.5 0.26 11.2 10.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 RUS89027.1 - 3.8 7.5 7.2 29 4.6 4.2 2.8 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) ANF_receptor PF01094.28 RUS89029.1 - 2.9e-12 46.4 0.0 2e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Toprim_C_rpt PF13368.6 RUS89029.1 - 0.1 12.6 0.0 2.4e+02 1.8 0.0 4.2 4 0 0 4 4 4 0 Topoisomerase C-terminal repeat ANF_receptor PF01094.28 RUS89030.1 - 0.00035 19.8 0.0 0.00048 19.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DNA_pol_phi PF04931.13 RUS89030.1 - 0.00058 18.1 31.5 0.00068 17.9 31.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi Peripla_BP_6 PF13458.6 RUS89030.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein FtsX PF02687.21 RUS89030.1 - 0.17 12.3 4.3 0.71 10.4 0.2 2.1 2 0 0 2 2 2 0 FtsX-like permease family eIF-3c_N PF05470.12 RUS89030.1 - 0.96 7.7 4.2 1.2 7.4 4.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Myc_target_1 PF15179.6 RUS89030.1 - 1.6 8.6 2.4 9.8 6.0 0.5 2.1 2 0 0 2 2 2 0 Myc target protein 1 Mpp10 PF04006.12 RUS89030.1 - 9.3 4.5 21.0 12 4.2 21.0 1.0 1 0 0 1 1 1 0 Mpp10 protein RVT_1 PF00078.27 RUS89031.1 - 8.9e-09 35.2 0.2 2e-08 34.0 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 RUS89031.1 - 1.1e-07 31.6 3.0 4.8e-07 29.6 0.0 2.9 3 1 1 4 4 4 1 Endonuclease-reverse transcriptase Guanylate_cyc PF00211.20 RUS89032.1 - 3.2e-67 225.7 0.0 2.5e-61 206.5 0.0 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS89032.1 - 3.9e-21 75.5 0.0 6.8e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89032.1 - 3.6e-19 69.1 0.0 6.6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 RUS89032.1 - 2.5e-06 27.1 1.0 3.8e-06 26.5 1.0 1.2 1 0 0 1 1 1 1 Heme NO binding associated Transcrip_act PF04949.13 RUS89033.1 - 0.0015 18.4 11.8 0.0028 17.6 11.8 1.4 1 0 0 1 1 1 1 Transcriptional activator CNOT1_HEAT PF16418.5 RUS89033.1 - 0.021 14.9 0.4 0.072 13.2 0.2 1.8 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF1327 PF07041.11 RUS89033.1 - 0.056 13.5 0.5 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) Macoilin PF09726.9 RUS89033.1 - 0.096 11.2 18.5 0.11 11.0 18.5 1.0 1 0 0 1 1 1 0 Macoilin family Methyltr_RsmB-F PF01189.17 RUS89034.1 - 1.4e-71 240.3 0.0 2.3e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 RUS89034.1 - 3.7e-06 27.3 0.0 8.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 RUS89034.1 - 0.00071 19.7 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase VWA PF00092.28 RUS89035.1 - 9.3e-166 547.0 0.5 8.4e-25 88.0 0.0 7.0 7 0 0 7 7 7 7 von Willebrand factor type A domain VWA_2 PF13519.6 RUS89035.1 - 6.1e-46 155.5 0.0 3.6e-06 27.6 0.0 7.3 7 0 0 7 7 7 7 von Willebrand factor type A domain RuvX PF03652.15 RUS89035.1 - 0.0035 17.7 0.1 4.9 7.5 0.0 4.5 5 0 0 5 5 5 1 Holliday junction resolvase HARP PF07443.13 RUS89035.1 - 0.0041 16.7 0.0 15 5.4 0.0 3.5 3 0 0 3 3 3 1 HepA-related protein (HARP) DUF2219 PF09982.9 RUS89035.1 - 0.027 13.7 0.0 14 4.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2219) GTP_EFTU_D4 PF14578.6 RUS89035.1 - 0.065 13.1 1.0 18 5.3 0.0 3.5 5 0 0 5 5 5 0 Elongation factor Tu domain 4 DUF3081 PF11280.8 RUS89035.1 - 7 6.6 6.8 24 4.8 0.3 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3081) VWA PF00092.28 RUS89036.1 - 2e-17 64.0 0.1 2.5e-09 37.6 0.0 2.5 2 1 1 3 3 3 2 von Willebrand factor type A domain DUF3081 PF11280.8 RUS89036.1 - 0.001 18.8 2.6 0.56 10.1 0.5 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3081) CNOT1_HEAT PF16418.5 RUS89036.1 - 0.051 13.7 0.0 14 5.8 0.0 2.2 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat zf-RING_4 PF14570.6 RUS89037.1 - 0.014 15.1 3.2 0.029 14.2 3.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3915 PF13054.6 RUS89038.1 - 0.31 11.0 2.1 0.4 10.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Auts2 PF15336.6 RUS89038.1 - 0.56 10.3 2.9 0.7 10.0 2.9 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Innexin PF00876.18 RUS89039.1 - 1.8e-122 409.0 11.6 2.1e-122 408.8 11.6 1.0 1 0 0 1 1 1 1 Innexin HepII_C PF18675.1 RUS89039.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Heparinase II C-terminal domain Chaperone_III PF07824.12 RUS89040.1 - 1.4 9.2 9.0 25 5.1 0.1 3.6 1 1 4 5 5 5 0 Type III secretion chaperone domain p12I PF12233.8 RUS89040.1 - 8.7 6.9 20.7 1.4e+04 -3.3 20.6 2.7 1 1 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein DUF3240 PF11582.8 RUS89041.1 - 0.0011 19.0 2.0 0.77 9.9 0.1 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF3240) DUF3185 PF11381.8 RUS89041.1 - 0.0015 18.5 2.3 8.6 6.5 0.1 3.5 1 1 1 3 3 3 2 Protein of unknown function (DUF3185) ComGG PF14173.6 RUS89041.1 - 0.0028 18.0 15.3 1.7 9.1 2.7 3.3 1 1 0 2 2 2 2 ComG operon protein 7 DUF249 PF03158.13 RUS89041.1 - 0.0034 17.1 3.0 0.098 12.3 0.6 2.2 1 1 1 2 2 2 2 Multigene family 530 protein WIF PF02019.18 RUS89041.1 - 0.11 12.2 6.2 0.38 10.5 5.6 2.0 1 1 0 1 1 1 0 WIF domain MPS-4 PF17523.2 RUS89041.1 - 0.19 11.9 2.7 34 4.7 0.1 3.0 1 1 3 4 4 4 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 PIN7 PF18475.1 RUS89041.1 - 0.25 12.0 6.2 2.6 8.7 1.1 2.1 1 1 1 2 2 2 0 PIN domain Rbsn PF11464.8 RUS89041.1 - 0.28 10.9 3.5 36 4.2 0.1 3.7 3 1 2 5 5 5 0 Rabenosyn Rab binding domain BNIP2 PF12496.8 RUS89041.1 - 0.51 10.8 2.8 3.5 8.1 0.6 2.2 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cys_rich_VLP PF14194.6 RUS89041.1 - 0.71 10.0 6.6 89 3.3 0.2 5.1 1 1 6 7 7 7 0 Cysteine-rich VLP DUF4005 PF13178.6 RUS89041.1 - 0.75 10.5 19.9 10 6.8 0.5 5.9 1 1 3 4 4 4 0 Protein of unknown function (DUF4005) YebF PF13995.6 RUS89041.1 - 0.78 9.8 7.0 19 5.3 2.7 3.0 1 1 1 2 2 2 0 YebF-like protein TPM_phosphatase PF04536.14 RUS89041.1 - 1.6 8.9 7.4 7.8 6.7 0.7 2.4 1 1 1 2 2 2 0 TPM domain Sacchrp_dh_NADP PF03435.18 RUS89041.1 - 2 8.7 6.1 1.2e+02 3.0 6.0 2.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4816 PF16086.5 RUS89043.1 - 0.91 9.5 40.6 1.8e+04 -27.9 40.6 6.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4816) Homeodomain PF00046.29 RUS89044.1 - 1e-22 79.7 3.6 2.3e-22 78.6 3.6 1.7 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 RUS89044.1 - 1e-12 47.0 0.0 2.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain Homeobox_KN PF05920.11 RUS89044.1 - 0.0038 17.1 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain ArAE_2_N PF10337.9 RUS89045.1 - 0.08 12.0 1.1 0.1 11.6 1.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Dicty_REP PF05086.12 RUS89045.1 - 0.4 8.6 7.5 0.46 8.4 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.22 RUS89046.1 - 4.5e-99 332.3 0.0 5.1e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS89047.1 - 1.7e-68 231.5 0.1 1.1e-45 156.2 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 BcrAD_BadFG PF01869.20 RUS89048.1 - 3e-19 69.6 0.1 4.1e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family P34-Arc PF04045.14 RUS89049.1 - 7.9e-103 343.3 2.1 9.7e-103 343.0 2.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Hist_deacetyl PF00850.19 RUS89050.1 - 1.9e-77 260.8 0.0 1.9e-77 260.8 0.0 2.2 2 1 0 2 2 2 1 Histone deacetylase domain Chorion_2 PF03964.15 RUS89050.1 - 9.9 7.1 7.7 4.4 8.2 0.2 3.2 3 0 0 3 3 3 0 Chorion family 2 HDAC4_Gln PF12203.8 RUS89051.1 - 0.00035 20.7 30.2 0.00035 20.7 30.2 1.7 2 0 0 2 2 2 1 Glutamine rich N terminal domain of histone deacetylase 4 CEP19 PF14933.6 RUS89051.1 - 0.11 12.7 8.0 0.15 12.3 8.0 1.2 1 0 0 1 1 1 0 CEP19-like protein RhoGAP PF00620.27 RUS89053.1 - 9.8e-40 135.9 0.0 1.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 RUS89053.1 - 1.6e-08 34.3 2.8 3.6e-08 33.2 2.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CxC3 PF18804.1 RUS89053.1 - 0.055 13.3 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Tropomyosin_1 PF12718.7 RUS89054.1 - 0.00047 20.3 7.5 0.00047 20.3 7.5 1.9 2 0 0 2 2 2 1 Tropomyosin like AbiH PF14253.6 RUS89054.1 - 0.0016 18.4 1.2 0.0016 18.4 1.2 1.4 2 0 0 2 2 2 1 Bacteriophage abortive infection AbiH Uso1_p115_C PF04871.13 RUS89054.1 - 0.0058 17.0 4.7 0.0058 17.0 4.7 2.3 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 RUS89054.1 - 0.0089 16.0 10.7 0.017 15.2 10.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4349 PF14257.6 RUS89054.1 - 0.011 15.3 2.2 0.054 12.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3037 PF11236.8 RUS89054.1 - 0.012 16.1 2.2 0.09 13.2 2.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) Golgin_A5 PF09787.9 RUS89054.1 - 0.026 14.0 9.4 0.041 13.3 9.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 RUS89054.1 - 1.9 7.3 4.0 1.8 7.4 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 RUS89054.1 - 7.9 4.2 7.6 14 3.5 7.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 RUS89054.1 - 8.6 6.1 19.0 13 5.5 18.9 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CCDC-167 PF15188.6 RUS89054.1 - 8.7 6.8 8.5 25 5.3 8.3 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Transglut_core PF01841.19 RUS89055.1 - 3.7e-15 56.4 0.0 3.4e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase-like superfamily Big_3_4 PF13754.6 RUS89055.1 - 0.047 13.4 0.1 5.4 6.8 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function EphA2_TM PF14575.6 RUS89056.1 - 0.0025 18.7 0.4 0.017 16.0 0.0 2.4 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Activin_recp PF01064.23 RUS89056.1 - 1.3 10.1 13.1 3.1 8.9 13.1 1.7 1 0 0 1 1 1 0 Activin types I and II receptor domain Pkinase_Tyr PF07714.17 RUS89057.1 - 4.4e-58 196.6 0.0 6.4e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89057.1 - 7.5e-48 163.2 0.0 1.5e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 RUS89057.1 - 1.5e-10 41.0 0.1 3.6e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS89057.1 - 2.3e-09 37.5 0.2 4.7e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3552 PF12072.8 RUS89057.1 - 2 7.8 6.4 3.4 7.0 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) NHL PF01436.21 RUS89058.1 - 6.2e-54 177.4 15.1 5.1e-09 35.7 0.1 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 RUS89058.1 - 1.1e-17 64.3 8.6 2.3e-08 33.6 0.2 4.1 2 1 2 4 4 4 4 6-bladed beta-propeller SGL PF08450.12 RUS89058.1 - 6.4e-11 42.3 0.2 0.0084 15.7 0.0 3.4 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region zf-RING_UBOX PF13445.6 RUS89058.1 - 5.6e-08 32.7 7.0 5.6e-08 32.7 7.0 2.6 3 0 0 3 3 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS89058.1 - 2.4e-07 30.5 7.5 2.4e-07 30.5 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Phytase-like PF13449.6 RUS89058.1 - 1e-05 25.6 0.1 0.05 13.5 0.0 3.8 3 1 0 3 3 3 1 Esterase-like activity of phytase TolB_like PF15869.5 RUS89058.1 - 3.4e-05 23.2 0.0 0.0019 17.5 0.0 2.3 1 1 1 2 2 2 1 TolB-like 6-blade propeller-like Lactonase PF10282.9 RUS89058.1 - 7.4e-05 22.2 0.0 0.00082 18.7 0.0 2.2 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller zf-C3HC4_4 PF15227.6 RUS89058.1 - 0.00018 21.6 9.1 0.00018 21.6 9.1 2.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RUS89058.1 - 0.00025 20.8 25.8 0.0003 20.6 7.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS89058.1 - 0.00028 20.7 8.8 0.00028 20.7 8.8 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS89058.1 - 0.00035 20.4 7.2 0.00035 20.4 7.2 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Arylesterase PF01731.20 RUS89058.1 - 0.0033 17.6 0.0 4 7.7 0.0 3.5 4 0 0 4 4 4 1 Arylesterase ARA70 PF12489.8 RUS89058.1 - 0.23 11.7 0.3 0.45 10.7 0.3 1.4 1 0 0 1 1 1 0 Nuclear coactivator zf-B_box PF00643.24 RUS89058.1 - 3.4 7.9 15.3 0.27 11.4 9.5 2.3 2 0 0 2 2 2 0 B-box zinc finger Kelch_1 PF01344.25 RUS89059.1 - 1.8e-56 187.5 1.6 1.8e-13 49.8 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS89059.1 - 4.8e-33 112.3 0.2 2.9e-07 30.6 0.0 6.6 4 2 2 6 6 6 5 Kelch motif BACK PF07707.15 RUS89059.1 - 2.6e-29 101.4 1.6 6.1e-29 100.2 0.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS89059.1 - 5e-28 97.5 0.9 9.6e-28 96.6 0.9 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RUS89059.1 - 7.4e-26 89.1 0.9 1.6e-05 24.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 RUS89059.1 - 1.5e-25 88.9 0.0 5.4e-05 23.4 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS89059.1 - 4e-25 87.6 0.1 2.6e-05 24.1 0.0 6.4 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS89059.1 - 1.7e-08 34.2 2.5 0.11 12.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 RUS89059.1 - 7.8e-05 23.0 0.0 2.8 8.5 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain DUF1668 PF07893.13 RUS89059.1 - 0.0049 16.3 0.0 1.5 8.1 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1668) Arf PF00025.21 RUS89060.1 - 4.3e-77 257.5 0.1 5.1e-77 257.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RUS89060.1 - 7.3e-14 52.0 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS89060.1 - 1.4e-12 47.6 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RUS89060.1 - 1.8e-12 47.1 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS89060.1 - 7e-12 45.2 1.5 3e-08 33.2 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS89060.1 - 6.1e-11 42.1 0.0 7.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS89060.1 - 1.5e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RUS89060.1 - 0.022 14.1 0.3 0.047 13.0 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arf PF00025.21 RUS89061.1 - 7.7e-79 263.2 0.1 9e-79 263.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS89061.1 - 2.1e-14 53.4 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RUS89061.1 - 2.4e-14 53.6 0.0 3.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS89061.1 - 1.3e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 RUS89061.1 - 4.9e-11 42.4 0.9 3.9e-07 29.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RUS89061.1 - 7.8e-11 41.8 0.0 9.4e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RUS89061.1 - 9.8e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RUS89061.1 - 0.0017 17.7 0.3 0.025 13.9 0.1 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TM2 PF05154.16 RUS89063.1 - 1.4e-14 54.1 6.9 3.1e-14 53.0 6.9 1.6 1 0 0 1 1 1 1 TM2 domain DUF1350 PF07082.11 RUS89064.1 - 0.063 12.6 0.2 5.1 6.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1350) CagS PF16707.5 RUS89064.1 - 0.34 10.9 8.2 15 5.5 1.5 3.6 1 1 2 3 3 3 0 Cag pathogenicity island protein S of Helicobacter pylori 7tm_1 PF00001.21 RUS89066.1 - 2.8e-11 43.3 11.9 4e-11 42.7 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS89066.1 - 5e-09 36.2 5.6 5e-09 36.2 5.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 5-FTHF_cyc-lig PF01812.20 RUS89067.1 - 9.3e-48 162.6 0.0 1.1e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Mg296 PF09644.10 RUS89068.1 - 0.25 11.5 2.2 0.17 12.0 0.3 1.6 2 0 0 2 2 2 0 Mg296 protein DUF4587 PF15248.6 RUS89068.1 - 1.1 10.1 9.9 1.2 10.0 3.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4587) Sec1 PF00995.23 RUS89069.1 - 9.2e-102 342.1 0.2 1e-101 342.0 0.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF3475 PF11961.8 RUS89069.1 - 0.062 13.4 0.1 0.39 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) SNRNP27 PF08648.12 RUS89070.1 - 5.7e-30 103.2 2.9 1.1e-29 102.3 2.9 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF2457 PF10446.9 RUS89070.1 - 0.00042 19.6 15.2 0.00042 19.6 15.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) UBA_3 PF09288.10 RUS89070.1 - 0.073 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain QWRF PF04484.12 RUS89070.1 - 1.7 8.3 12.1 2.2 7.9 12.1 1.1 1 0 0 1 1 1 0 QWRF family 7tm_1 PF00001.21 RUS89071.1 - 5.5e-82 275.0 0.0 8.5e-82 274.4 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS89071.1 - 3.4e-06 26.6 10.0 1.8e-05 24.2 4.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS89071.1 - 9.5e-06 25.4 11.8 9.5e-06 25.4 11.8 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS89071.1 - 4.9e-05 23.2 6.0 0.00069 19.4 4.8 2.2 2 0 0 2 2 2 1 Olfactory receptor DUF429 PF04250.13 RUS89071.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Pox_I5 PF04713.12 RUS89071.1 - 2.2 8.4 7.3 0.39 10.8 2.8 2.0 2 0 0 2 2 2 0 Poxvirus protein I5 Anillin PF08174.11 RUS89072.1 - 0.056 13.9 0.4 0.12 12.8 0.4 1.6 1 0 0 1 1 1 0 Cell division protein anillin ANAPC4_WD40 PF12894.7 RUS89073.1 - 3.5e-29 100.9 0.1 3.7e-05 23.9 0.0 6.8 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS89073.1 - 5e-26 90.4 12.9 1.7e-05 25.5 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 RUS89073.1 - 4.1e-10 39.9 0.0 1.8e-05 24.7 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RUS89073.1 - 7e-06 25.8 0.0 0.0025 17.7 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.11 RUS89073.1 - 0.00014 20.9 0.0 0.016 14.1 0.0 2.3 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 RUS89073.1 - 0.00059 18.9 0.0 2.1 7.2 0.0 3.9 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 RUS89073.1 - 0.001 18.2 0.0 0.078 12.0 0.0 2.7 1 1 2 3 3 3 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 RUS89073.1 - 0.0029 16.2 0.1 0.016 13.7 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 RUS89073.1 - 0.017 14.7 0.0 0.052 13.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 RUS89073.1 - 0.018 14.4 0.0 0.1 11.9 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain IKI3 PF04762.12 RUS89073.1 - 0.061 11.3 0.0 1.4 6.9 0.0 2.1 1 1 0 1 1 1 0 IKI3 family Nup160 PF11715.8 RUS89073.1 - 0.066 11.8 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Frtz PF11768.8 RUS89073.1 - 0.13 10.6 0.0 8.4 4.6 0.0 2.3 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Forkhead PF00250.18 RUS89075.1 - 4.3e-37 126.3 0.0 7.8e-37 125.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Ank_2 PF12796.7 RUS89076.1 - 1.1e-28 99.6 8.3 1.1e-13 51.6 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS89076.1 - 7.3e-23 80.6 6.3 7.5e-13 48.7 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS89076.1 - 4.8e-22 77.4 9.9 1.6e-05 25.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS89076.1 - 1.7e-19 69.6 6.5 1.3e-06 28.6 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89076.1 - 8.9e-19 65.6 7.1 0.00018 21.7 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat DUF249 PF03158.13 RUS89076.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein Fucose_iso_C PF02952.17 RUS89077.1 - 0.0039 16.9 0.0 0.81 9.4 0.0 2.1 1 1 1 2 2 2 2 L-fucose isomerase, C-terminal domain DUF3496 PF12001.8 RUS89077.1 - 0.11 12.9 0.0 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) p450 PF00067.22 RUS89078.1 - 6.9e-102 341.6 0.0 8.1e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Erg28 PF03694.13 RUS89079.1 - 3.9e-09 36.9 1.8 5.2e-09 36.5 1.8 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF4282 PF14110.6 RUS89079.1 - 0.12 13.1 4.0 0.1 13.3 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Ldl_recept_a PF00057.18 RUS89080.1 - 2.7e-08 33.9 2.9 4.7e-08 33.1 2.9 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A COesterase PF00135.28 RUS89081.1 - 3.4e-53 181.3 0.9 4.4e-53 180.9 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS89081.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-C3HC4_2 PF13923.6 RUS89082.1 - 7.9e-11 41.6 2.6 7.9e-11 41.6 2.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS89082.1 - 6.6e-10 38.7 3.7 6.6e-10 38.7 3.7 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS89082.1 - 9e-10 38.4 5.7 9e-10 38.4 5.7 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RUS89082.1 - 1.4e-09 38.0 2.4 1.4e-09 38.0 2.4 3.3 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RUS89082.1 - 1.6e-06 28.0 5.8 1.6e-06 28.0 5.8 3.2 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS89082.1 - 3e-05 24.2 11.8 3e-05 24.2 11.8 3.9 2 2 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS89082.1 - 4.7e-05 23.2 2.9 4.7e-05 23.2 2.9 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 RUS89082.1 - 0.00039 20.2 1.0 0.00039 20.2 1.0 2.2 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.16 RUS89082.1 - 0.00061 19.8 2.6 0.00084 19.3 2.6 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_6 PF14835.6 RUS89082.1 - 0.0014 18.4 0.6 0.0014 18.4 0.6 2.6 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 RUS89082.1 - 0.0043 17.5 5.8 0.0043 17.5 5.8 2.4 2 2 0 2 2 2 1 TRAF-like zinc-finger zf-ANAPC11 PF12861.7 RUS89082.1 - 0.013 15.5 2.0 0.013 15.5 2.0 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 RUS89082.1 - 0.017 15.0 5.9 0.017 15.0 5.9 4.1 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 zf-ACC PF17848.1 RUS89082.1 - 0.042 13.9 4.2 7.9 6.7 0.0 3.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain U-box PF04564.15 RUS89082.1 - 0.063 13.5 0.0 0.092 12.9 0.0 1.4 1 1 0 1 1 1 0 U-box domain zf-RING_10 PF16685.5 RUS89082.1 - 0.069 13.3 4.8 0.069 13.3 4.8 2.7 3 1 0 3 3 3 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 RUS89082.1 - 0.11 12.5 15.3 0.7 9.9 1.1 3.2 2 1 1 3 3 3 0 zinc-ribbons zf-WRNIP1_ubi PF18279.1 RUS89082.1 - 0.11 13.2 6.5 7.5 7.4 0.4 3.8 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain UPF0547 PF10571.9 RUS89082.1 - 0.88 9.7 0.2 0.88 9.7 0.2 4.1 5 0 0 5 5 4 0 Uncharacterised protein family UPF0547 SART-1 PF03343.13 RUS89083.1 - 1.3e-131 440.2 51.5 1.3e-131 440.2 51.5 3.0 2 1 0 2 2 2 1 SART-1 family Ribosomal_60s PF00428.19 RUS89083.1 - 2.6 8.7 9.1 2 9.1 1.1 3.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein OATP PF03137.20 RUS89084.1 - 2e-107 359.8 14.9 2.4e-107 359.5 14.9 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 RUS89084.1 - 9.2e-16 57.7 21.7 9.8e-13 47.7 5.4 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 RUS89084.1 - 0.002 18.2 7.4 0.005 16.9 7.4 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain NADH-u_ox-rdase PF10785.9 RUS89084.1 - 0.27 11.9 1.0 1.3 9.7 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Rap_GAP PF02145.15 RUS89085.1 - 6.4e-66 221.5 0.3 1.1e-65 220.6 0.3 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.24 RUS89085.1 - 5.9e-07 29.8 0.0 1.6e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain SPAR_C PF11881.8 RUS89085.1 - 1.7e-06 28.2 2.6 1.7e-06 28.2 2.6 4.2 4 0 0 4 4 4 1 C-terminal domain of SPAR protein PDZ_6 PF17820.1 RUS89085.1 - 3.7e-05 23.5 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain TRAPPC10 PF12584.8 RUS89086.1 - 0.00017 21.4 0.3 1.4 8.6 0.0 3.7 1 1 2 3 3 3 2 Trafficking protein particle complex subunit 10, TRAPPC10 7tm_1 PF00001.21 RUS89087.1 - 4.4e-13 49.2 21.0 5.7e-13 48.8 21.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MoeA_N PF03453.17 RUS89088.1 - 4e-45 153.4 3.5 1.1e-44 152.0 3.5 1.8 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 RUS89088.1 - 1.7e-29 102.3 0.1 8e-25 87.2 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.15 RUS89088.1 - 1.1e-09 38.3 0.0 6.1e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 MoeA C-terminal region (domain IV) RAP1 PF07218.11 RUS89088.1 - 2.9 6.0 5.8 4.1 5.6 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 RUS89088.1 - 4.6 5.7 6.9 6.3 5.2 6.9 1.1 1 0 0 1 1 1 0 Macoilin family EGF PF00008.27 RUS89089.1 - 0.0031 17.8 3.7 0.01 16.1 3.7 2.0 1 0 0 1 1 1 1 EGF-like domain RFX5_DNA_bdg PF14621.6 RUS89089.1 - 0.016 15.0 0.3 0.039 13.7 0.3 1.6 1 0 0 1 1 1 0 RFX5 DNA-binding domain Sof1 PF04158.14 RUS89089.1 - 0.071 13.4 2.3 0.23 11.8 1.3 2.4 2 0 0 2 2 2 0 Sof1-like domain DMAP_binding PF06464.11 RUS89089.1 - 8.6 7.2 8.7 2.8 8.8 0.9 3.2 3 0 0 3 3 3 0 DMAP1-binding Domain ABC2_membrane_3 PF12698.7 RUS89090.1 - 1.1e-57 195.7 37.5 1.4e-36 126.3 27.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 RUS89090.1 - 3.3e-39 134.6 0.0 7.9e-27 94.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RUS89090.1 - 5.9e-18 65.7 0.0 7.7e-07 29.2 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 RUS89090.1 - 0.0004 20.6 0.0 1.3 9.4 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 RUS89090.1 - 0.0045 16.7 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 RUS89090.1 - 0.024 14.1 0.0 10 5.4 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RUS89090.1 - 0.069 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 RUS89090.1 - 0.17 11.3 59.7 0.018 14.5 7.5 5.2 5 0 0 5 5 5 0 ABC-2 type transporter ELFV_dehydrog_N PF02812.18 RUS89092.1 - 2.2e-58 195.8 0.0 4.3e-58 194.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 RUS89092.1 - 5.7e-52 176.9 0.2 7e-48 163.5 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L1 PF00687.21 RUS89093.1 - 2e-07 30.9 0.0 7e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Exo_endo_phos PF03372.23 RUS89094.1 - 5e-18 65.5 0.0 1.4e-16 60.8 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IMUP PF15761.5 RUS89094.1 - 0.13 12.9 2.2 0.23 12.2 2.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein TMEM72 PF16054.5 RUS89095.1 - 6.7e-33 113.9 1.0 7.8e-33 113.7 1.0 1.0 1 0 0 1 1 1 1 Transmembrane protein family 72 Cg6151-P PF10233.9 RUS89095.1 - 0.0016 18.7 5.6 0.0037 17.5 5.6 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4064 PF13273.6 RUS89095.1 - 0.0027 17.9 1.9 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 RUS89097.1 - 8.5e-17 61.6 1.0 1.1e-16 61.2 1.0 1.1 1 0 0 1 1 1 1 Tetraspanin family Glyco_hydro_79n PF03662.14 RUS89098.1 - 1.7e-23 83.1 0.0 2.3e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Endonuclease_NS PF01223.23 RUS89099.1 - 2.8e-31 109.1 0.0 3.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease TFIIB PF00382.19 RUS89100.1 - 1.4e-47 159.6 2.6 2.2e-24 85.3 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 RUS89100.1 - 1.8e-14 53.0 0.1 2.9e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 RUS89100.1 - 1.1e-07 31.9 0.1 2e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 RUS89100.1 - 8e-05 22.4 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS89100.1 - 0.004 17.2 0.2 0.67 10.1 0.1 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain Rrf2 PF02082.20 RUS89100.1 - 0.015 15.6 0.1 7.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator Endonuclease_NS PF01223.23 RUS89101.1 - 2.1e-65 220.7 3.2 2.5e-65 220.5 3.2 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 RUS89101.1 - 0.079 13.1 2.4 0.32 11.1 2.5 1.9 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease RNase_H_2 PF13482.6 RUS89102.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.4 1 1 1 2 2 2 0 RNase_H superfamily Neur_chan_LBD PF02931.23 RUS89103.1 - 2.2e-33 115.5 0.0 3.2e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS89103.1 - 2.6e-14 53.9 0.0 2.6e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region TMEM154 PF15102.6 RUS89104.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Ninjurin PF04923.12 RUS89104.1 - 0.094 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Ninjurin Cytochrome-c551 PF10643.9 RUS89105.1 - 0.043 13.4 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DSHCT PF08148.12 RUS89106.1 - 4.4e-48 163.0 1.4 9.2e-48 162.0 1.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 RUS89106.1 - 1.2e-29 104.0 0.0 2.3e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain Ski2_N PF17911.1 RUS89106.1 - 6.3e-25 87.6 0.0 3.2e-24 85.3 0.0 2.0 2 0 0 2 2 2 1 Ski2 N-terminal region DEAD PF00270.29 RUS89106.1 - 9.4e-18 64.6 0.1 2.1e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS89106.1 - 6.8e-07 29.6 0.0 1.9e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS89106.1 - 9.7e-06 25.7 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WAP PF00095.21 RUS89108.1 - 1.9e-16 60.1 38.9 3.5e-10 40.1 15.0 3.2 3 1 0 3 3 3 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' TRIQK PF15168.6 RUS89108.1 - 0.18 11.7 0.9 0.35 10.8 0.9 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family TBK1_ULD PF18396.1 RUS89109.1 - 0.2 11.6 0.0 0.65 10.0 0.0 1.7 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain UPRTase PF14681.6 RUS89110.1 - 3.5e-43 147.5 0.0 4.6e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RUS89110.1 - 0.0098 15.4 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Sushi PF00084.20 RUS89111.1 - 0.00013 22.5 0.1 0.00019 21.9 0.1 1.3 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Pox_I5 PF04713.12 RUS89111.1 - 0.13 12.3 0.2 0.34 11.0 0.1 1.7 2 0 0 2 2 2 0 Poxvirus protein I5 Plant_zn_clust PF10533.9 RUS89111.1 - 0.37 10.8 4.1 0.43 10.6 0.9 2.2 2 0 0 2 2 2 0 Plant zinc cluster domain DUF1075 PF06388.11 RUS89112.1 - 6.2e-12 45.6 0.2 7e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) YtpI PF14007.6 RUS89112.1 - 0.013 15.6 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 YtpI-like protein RNase_H PF00075.24 RUS89113.1 - 5.2e-10 39.7 1.4 2.1e-09 37.7 0.1 2.4 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 RUS89113.1 - 0.00026 20.8 0.0 0.00062 19.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4864 PF16156.5 RUS89113.1 - 0.092 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Insulin PF00049.18 RUS89115.1 - 2.7e-07 31.5 2.7 7.8e-07 30.0 2.7 1.8 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family DUF3376 PF11856.8 RUS89115.1 - 0.053 12.5 0.1 0.057 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) RPN7 PF10602.9 RUS89116.1 - 4.8e-61 205.5 2.6 8.6e-61 204.6 2.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RUS89116.1 - 4.6e-16 59.2 0.1 1.3e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain SOAR PF16533.5 RUS89116.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region BACK PF07707.15 RUS89118.1 - 1.7e-17 63.4 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch NYD-SP28 PF14772.6 RUS89119.1 - 0.017 15.1 0.2 0.041 13.9 0.0 1.6 2 0 0 2 2 2 0 Sperm tail Guanylate_cyc PF00211.20 RUS89120.1 - 1.4e-54 184.5 0.0 1.9e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS89120.1 - 0.00085 18.8 2.1 0.00085 18.8 0.6 1.8 2 0 0 2 2 2 1 Heme NO binding associated PAX PF00292.18 RUS89120.1 - 0.017 15.0 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 'Paired box' domain NOA36 PF06524.12 RUS89120.1 - 0.022 14.1 24.0 0.032 13.5 24.0 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS89120.1 - 0.063 11.4 23.0 0.086 10.9 23.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 RUS89120.1 - 0.069 12.7 9.4 0.098 12.2 9.4 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 RUS89120.1 - 0.086 11.1 9.1 0.11 10.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RUS89120.1 - 0.51 9.6 9.6 0.65 9.3 9.6 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 RUS89120.1 - 0.53 10.5 18.8 0.8 9.9 18.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2076 PF09849.9 RUS89120.1 - 1 9.3 14.6 1.7 8.7 14.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop14 PF04147.12 RUS89120.1 - 1.1 7.4 15.2 1.4 7.0 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 RUS89120.1 - 1.9 7.5 31.9 2.6 7.1 31.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 RUS89120.1 - 3 7.8 15.3 2.3 8.2 12.6 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2796 PF10986.8 RUS89120.1 - 5.6 6.9 7.6 1.4 8.9 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Pkinase PF00069.25 RUS89121.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89121.1 - 1.8e-05 24.2 0.0 2.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Porphobil_deamC PF03900.15 RUS89121.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain ANF_receptor PF01094.28 RUS89122.1 - 7.7e-33 114.0 0.0 9.6e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region WBP-1 PF11669.8 RUS89123.1 - 0.0027 18.3 7.7 0.029 15.0 7.7 2.3 1 1 0 1 1 1 1 WW domain-binding protein 1 RCR PF12273.8 RUS89123.1 - 0.0031 18.2 0.0 0.0049 17.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.6 RUS89123.1 - 0.0044 17.3 4.1 0.0074 16.6 4.1 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 RUS89123.1 - 0.013 15.4 5.2 0.018 14.9 4.5 1.6 1 1 0 1 1 1 0 Transmembrane 52 EphA2_TM PF14575.6 RUS89123.1 - 0.014 16.3 0.0 0.022 15.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 RUS89123.1 - 0.22 11.8 2.7 0.43 10.9 2.7 1.5 1 0 0 1 1 1 0 LST-1 protein MLANA PF14991.6 RUS89123.1 - 1.2 9.4 3.8 5.5 7.3 3.8 2.0 1 1 0 1 1 1 0 Protein melan-A CYYR1 PF10873.8 RUS89123.1 - 4.8 7.6 14.5 9.5 6.6 14.5 1.6 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Pro_isomerase PF00160.21 RUS89124.1 - 4.4e-53 179.8 0.0 5e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DPM3 PF08285.11 RUS89125.1 - 1.2e-29 102.3 0.4 1.4e-29 102.1 0.4 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4250 PF14056.6 RUS89125.1 - 0.13 12.2 0.1 0.82 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF3011 PF11218.8 RUS89126.1 - 5.9e-09 36.2 0.1 9.2e-09 35.6 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3011) PAN_1 PF00024.26 RUS89126.1 - 0.00098 19.0 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 PAN domain Activator_LAG-3 PF11498.8 RUS89127.1 - 0.74 8.7 106.6 0.14 11.1 27.5 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 wnt PF00110.19 RUS89128.1 - 9.5e-118 393.3 23.9 1.1e-117 393.1 23.9 1.0 1 0 0 1 1 1 1 wnt family OCRE PF17780.1 RUS89129.1 - 0.2 11.7 2.8 14 5.8 0.1 3.3 3 0 0 3 3 3 0 OCRE domain Kelch_4 PF13418.6 RUS89130.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Tachylectin PF14517.6 RUS89130.1 - 0.037 13.6 1.7 0.074 12.6 1.7 1.5 1 1 0 1 1 1 0 Tachylectin OCRE PF17780.1 RUS89130.1 - 0.2 11.7 1.6 35 4.5 0.1 3.2 3 0 0 3 3 3 0 OCRE domain Pkinase PF00069.25 RUS89131.1 - 3.2e-43 148.0 0.0 6.6e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 RUS89131.1 - 6.5e-35 118.7 36.7 3.6e-12 45.9 2.0 6.8 2 2 3 6 6 6 6 Leucine rich repeat Pkinase_Tyr PF07714.17 RUS89131.1 - 3e-34 118.5 0.0 6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 RUS89131.1 - 4.6e-34 115.9 33.7 1.8e-07 31.3 0.8 7.7 5 1 3 8 8 8 8 Leucine Rich repeats (2 copies) Roc PF08477.13 RUS89131.1 - 5.3e-28 97.7 0.0 6.3e-27 94.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 RUS89131.1 - 1.7e-24 86.7 0.1 3.3e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 RUS89131.1 - 1.2e-14 54.2 0.0 7.5e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Ras family LRR_9 PF14580.6 RUS89131.1 - 2.1e-08 33.9 11.7 0.0067 15.9 0.5 3.8 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 RUS89131.1 - 2.5e-07 30.3 29.2 15 6.6 0.2 11.5 12 0 0 12 12 11 0 Leucine Rich Repeat MMR_HSR1 PF01926.23 RUS89131.1 - 3.6e-05 23.8 0.0 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase LRR_5 PF13306.6 RUS89131.1 - 6.2e-05 23.0 1.4 0.047 13.7 0.3 3.1 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Gtr1_RagA PF04670.12 RUS89131.1 - 8.1e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 RUS89131.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_2 PF12796.7 RUS89131.1 - 0.00057 20.4 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS89131.1 - 0.013 16.0 0.0 19 6.2 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat FTA2 PF13095.6 RUS89131.1 - 0.02 14.5 0.0 2.7 7.6 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA_16 PF13191.6 RUS89131.1 - 0.023 15.1 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain LRR_6 PF13516.6 RUS89131.1 - 0.16 12.1 49.4 4.4 7.6 0.1 11.3 12 0 0 12 12 12 0 Leucine Rich repeat KKLCAg1 PF15204.6 RUS89131.1 - 0.68 10.1 4.1 0.59 10.3 0.1 2.9 3 0 0 3 3 3 0 Kita-kyushu lung cancer antigen 1 Urb2 PF10441.9 RUS89132.1 - 0.0098 15.8 0.2 0.021 14.8 0.2 1.5 1 0 0 1 1 1 1 Urb2/Npa2 family ORC5_C PF14630.6 RUS89133.1 - 2.9e-63 214.1 0.2 3.6e-63 213.7 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 RUS89133.1 - 1.8e-17 64.2 0.0 3.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RUS89133.1 - 3.5e-09 37.0 0.0 1.6e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RUS89133.1 - 0.00071 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 RUS89133.1 - 0.0037 17.7 0.0 0.072 13.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RUS89133.1 - 0.0049 16.4 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 RUS89133.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 RUS89133.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 RUS89133.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RUS89133.1 - 0.066 13.6 0.1 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 RUS89133.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sushi PF00084.20 RUS89134.1 - 5.9e-25 87.6 31.0 1.9e-08 34.7 2.1 6.5 6 1 0 6 6 6 6 Sushi repeat (SCR repeat) HRM PF02793.22 RUS89134.1 - 0.034 14.4 23.9 0.055 13.8 0.1 4.8 5 1 0 5 5 5 0 Hormone receptor domain B9-C2 PF07162.11 RUS89135.1 - 7.2e-57 192.3 0.0 8.1e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Methyltransf_28 PF02636.17 RUS89136.1 - 1.2e-70 238.1 0.0 3.1e-70 236.8 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase UDPGP PF01704.18 RUS89137.1 - 7.3e-193 640.8 0.3 8.5e-193 640.6 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Vps54 PF07928.12 RUS89138.1 - 1.7e-47 161.2 2.2 3.3e-47 160.3 0.2 2.5 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 RUS89138.1 - 9.1e-14 51.4 15.0 3e-13 49.7 10.6 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex zf-BED PF02892.15 RUS89138.1 - 0.014 15.4 0.2 0.041 13.9 0.2 1.8 1 0 0 1 1 1 0 BED zinc finger Sec8_exocyst PF04048.14 RUS89138.1 - 1 9.3 7.3 0.31 10.9 3.1 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain zf-C2H2_4 PF13894.6 RUS89138.1 - 1.9 9.5 4.8 1.1 10.3 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger COG2 PF06148.11 RUS89138.1 - 8.7 6.4 9.1 8.1 6.5 2.7 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Neugrin PF06413.11 RUS89139.1 - 0.11 12.4 3.8 0.3 11.1 3.8 1.7 1 0 0 1 1 1 0 Neugrin DUF2981 PF11200.8 RUS89139.1 - 8.3 6.0 11.0 14 5.3 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) COX7a PF02238.15 RUS89140.1 - 1.4e-05 25.3 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII TBP PF00352.21 RUS89141.1 - 7.3e-67 221.4 0.1 1.1e-32 111.9 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RUS89141.1 - 7e-06 26.1 0.0 0.078 13.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PAS_11 PF14598.6 RUS89142.1 - 9.6e-25 86.9 0.0 1.6e-19 70.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 RUS89142.1 - 3.7e-20 72.0 0.0 2.9e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 RUS89142.1 - 3.1e-14 52.9 0.0 2.3e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 RUS89142.1 - 1.7e-05 25.0 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 RUS89142.1 - 8.5e-05 22.8 0.0 0.035 14.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 RUS89142.1 - 0.0014 18.6 0.7 0.0036 17.2 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Symplekin_C PF12295.8 RUS89143.1 - 1e-70 237.6 6.6 4.5e-70 235.5 6.6 2.2 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 RUS89143.1 - 4e-52 177.1 2.6 4e-52 177.1 2.6 4.4 5 0 0 5 5 5 2 Domain of unknown function (DUF3453) Yippee-Mis18 PF03226.14 RUS89145.1 - 7.1e-13 48.7 0.0 8.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 RUS89145.1 - 0.0015 18.3 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.15 RUS89145.1 - 0.0039 17.1 1.4 0.17 11.8 1.4 2.1 1 1 0 1 1 1 1 Recombination endonuclease VII RIG-I_C-RD PF11648.8 RUS89145.1 - 0.0074 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I SelR PF01641.18 RUS89145.1 - 0.014 15.4 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 SelR domain DUF5600 PF18150.1 RUS89146.1 - 1.5e-46 157.4 2.6 3.6e-46 156.1 2.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 RUS89146.1 - 2.9e-18 65.7 0.1 9.6e-18 64.1 0.1 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 RUS89146.1 - 6.9e-17 61.0 3.8 6.9e-17 61.0 3.8 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 RUS89146.1 - 1e-14 54.9 0.0 5.2e-14 52.6 0.0 2.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 RUS89146.1 - 2.8e-08 33.8 0.0 6.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 RUS89146.1 - 0.00053 19.4 0.1 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 RUS89146.1 - 0.0019 17.8 0.0 0.006 16.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 RUS89146.1 - 0.0069 16.6 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 RUS89146.1 - 0.012 15.9 0.0 0.043 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RUS89146.1 - 0.02 14.8 0.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Gtr1_RagA PF04670.12 RUS89146.1 - 0.032 13.6 0.1 0.14 11.5 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 RUS89146.1 - 0.17 11.5 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RUS89146.1 - 0.23 11.8 0.6 2.7 8.3 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain Ion_trans_2 PF07885.16 RUS89147.1 - 1.3e-10 41.0 6.7 3.6e-10 39.7 6.7 1.7 1 0 0 1 1 1 1 Ion channel DUF4752 PF15944.5 RUS89147.1 - 0.15 12.1 0.0 0.56 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) RVT_1 PF00078.27 RUS89149.1 - 3.2e-43 147.8 0.5 2.9e-42 144.7 0.5 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 RUS89149.1 - 5.4e-10 39.1 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 RRM_1 PF00076.22 RUS89151.1 - 1.9e-10 40.4 0.0 4.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS89151.1 - 0.00077 19.1 0.0 0.003 17.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 RUS89151.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.3 3 0 0 3 3 3 0 RL domain SARAF PF06682.12 RUS89152.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TNFR_16_TM PF18422.1 RUS89152.1 - 0.056 13.4 0.7 0.088 12.8 0.7 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TSP_1 PF00090.19 RUS89152.1 - 0.099 12.9 0.4 0.27 11.5 0.4 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain DDE_1 PF03184.19 RUS89153.1 - 5.3e-17 62.0 0.1 5.3e-17 62.0 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease FXa_inhibition PF14670.6 RUS89154.1 - 6.7e-40 135.1 116.4 1.7e-10 41.0 10.8 36.7 13 3 16 29 29 29 8 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 RUS89154.1 - 2e-38 130.3 631.4 7.4e-05 22.8 18.9 34.3 7 6 27 34 34 34 22 Laminin EGF domain cEGF PF12662.7 RUS89154.1 - 4.5e-23 80.8 54.6 7.3e-08 32.2 0.8 39.2 39 4 0 39 39 39 10 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS89154.1 - 4.6e-22 77.9 61.3 2.2e-08 34.2 9.1 35.1 23 7 11 34 34 34 5 Calcium-binding EGF domain EGF_2 PF07974.13 RUS89154.1 - 7.2e-06 26.3 79.8 0.00034 20.9 14.1 47.4 37 15 9 46 46 46 16 EGF-like domain EGF PF00008.27 RUS89154.1 - 0.0036 17.6 7.7 0.0036 17.6 7.7 39.7 40 3 0 40 40 40 18 EGF-like domain EGF_3 PF12947.7 RUS89154.1 - 0.0046 17.1 6.1 0.0046 17.1 6.1 33.2 31 3 1 32 32 32 6 EGF domain hEGF PF12661.7 RUS89154.1 - 0.012 16.2 32.3 0.015 15.9 4.0 42.5 39 6 1 40 40 40 0 Human growth factor-like EGF Guanylate_cyc PF00211.20 RUS89157.1 - 5e-42 143.6 0.7 3.1e-24 85.6 0.0 2.4 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 RUS89157.1 - 1.1e-12 48.9 0.0 3.2e-11 44.1 0.0 2.3 1 1 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 RUS89157.1 - 2.4e-06 27.2 2.5 0.00015 21.3 0.1 2.4 2 0 0 2 2 2 1 Heme NO binding associated Mpp10 PF04006.12 RUS89157.1 - 4.3e-05 22.2 13.9 5.7e-05 21.8 13.9 1.1 1 0 0 1 1 1 1 Mpp10 protein Plasmodium_Vir PF05795.11 RUS89157.1 - 0.0014 18.1 1.0 0.0017 17.9 1.0 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein BUD22 PF09073.10 RUS89157.1 - 0.0024 17.3 18.1 0.0034 16.8 18.1 1.1 1 0 0 1 1 1 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 RUS89157.1 - 0.0024 18.1 21.5 0.0027 18.0 20.5 1.6 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 V_ATPase_I PF01496.19 RUS89157.1 - 0.017 13.1 3.5 0.03 12.3 3.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 RUS89157.1 - 0.018 14.3 0.5 0.024 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF913 PF06025.12 RUS89157.1 - 0.02 13.9 1.8 0.03 13.3 1.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 RUS89157.1 - 0.026 14.7 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 DDHD domain Tropomodulin PF03250.14 RUS89157.1 - 0.061 13.4 11.9 0.13 12.3 11.9 1.5 1 0 0 1 1 1 0 Tropomodulin Pox_Ag35 PF03286.14 RUS89157.1 - 0.071 12.9 17.6 0.14 12.0 17.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoIIP PF07454.11 RUS89157.1 - 0.084 12.3 9.8 0.13 11.7 9.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 RUS89157.1 - 0.11 11.7 2.3 0.2 10.8 2.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 RUS89157.1 - 0.13 10.4 24.6 0.017 13.4 20.4 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 RUS89157.1 - 0.23 9.7 16.8 0.32 9.2 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 RUS89157.1 - 0.26 10.6 23.7 0.4 10.0 23.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FYDLN_acid PF09538.10 RUS89157.1 - 0.27 12.0 15.5 0.56 10.9 15.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MRNIP PF15749.5 RUS89157.1 - 0.28 11.9 8.7 0.54 11.0 8.7 1.4 1 0 0 1 1 1 0 MRN-interacting protein DUF4637 PF15470.6 RUS89157.1 - 0.33 10.7 21.6 0.63 9.7 21.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC27 PF09507.10 RUS89157.1 - 0.44 9.9 15.2 0.61 9.4 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 RUS89157.1 - 0.44 9.9 23.6 0.64 9.4 23.6 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 RUS89157.1 - 0.66 8.0 6.3 0.94 7.5 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR3 PF03666.13 RUS89157.1 - 0.78 8.5 8.1 1.1 7.9 8.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 RUS89157.1 - 0.81 9.5 17.0 1.4 8.7 17.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 RUS89157.1 - 0.88 8.3 14.4 2 7.1 9.8 2.1 2 0 0 2 2 2 0 Presenilin RPA43_OB PF17875.1 RUS89157.1 - 1.1 9.8 7.4 2.5 8.8 7.4 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RNA_pol_Rpc4 PF05132.14 RUS89157.1 - 1.1 9.6 8.2 2 8.8 8.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 RUS89157.1 - 1.4 7.0 29.9 2.2 6.3 29.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2151 PF10221.9 RUS89157.1 - 1.5 7.4 8.2 2.7 6.5 8.2 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator Serinc PF03348.15 RUS89157.1 - 1.6 7.6 3.3 2.6 6.9 3.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Eapp_C PF10238.9 RUS89157.1 - 2.5 8.2 8.3 4.3 7.4 8.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Vfa1 PF08432.10 RUS89157.1 - 2.9 8.2 16.9 5.4 7.3 16.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PTPRCAP PF15713.5 RUS89157.1 - 4.7 7.5 24.1 8.5 6.6 24.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Merozoite_SPAM PF07133.11 RUS89157.1 - 5.5 6.9 42.4 13 5.8 42.4 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RPN2_C PF18004.1 RUS89157.1 - 7.1 6.5 22.7 13 5.7 22.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 RUS89157.1 - 8.1 5.7 22.0 12 5.0 22.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-N PF05238.13 RUS89157.1 - 9.2 5.4 8.8 14 4.9 8.8 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Nop53 PF07767.11 RUS89157.1 - 10 5.4 29.3 17 4.7 29.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AA_permease PF00324.21 RUS89159.1 - 1.6e-25 89.6 20.7 1.6e-25 89.6 20.7 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 RUS89159.1 - 2.2e-24 86.1 20.0 2.2e-24 86.1 20.0 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 RUS89159.1 - 1.1e-15 57.4 1.3 3.9e-15 55.6 1.3 2.0 1 0 0 1 1 1 1 C-terminus of AA_permease Exo_endo_phos_2 PF14529.6 RUS89160.1 - 0.017 15.0 0.4 3.7 7.4 0.1 2.3 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase DUF5327 PF17261.2 RUS89161.1 - 0.044 14.5 6.8 0.15 12.8 6.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Spt20 PF12090.8 RUS89161.1 - 0.28 10.8 16.4 0.45 10.1 16.4 1.2 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 RUS89161.1 - 1.7 8.4 5.6 2.8 7.8 5.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus Suf PF05843.14 RUS89161.1 - 1.9 8.4 7.6 3.9 7.4 7.6 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 RUS89161.1 - 3 6.4 9.4 3.9 6.0 9.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Roughex PF06020.11 RUS89161.1 - 7.4 5.6 8.6 11 5.0 8.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2345 PF10106.9 RUS89162.1 - 0.00022 21.1 18.8 0.088 12.7 2.1 3.4 1 1 3 4 4 4 4 Uncharacterized protein conserved in bacteria (DUF2345) YopE PF03545.13 RUS89162.1 - 0.23 11.7 12.2 6.3 7.0 0.2 5.1 1 1 7 8 8 8 0 Yersinia virulence determinant (YopE) HTH_50 PF18024.1 RUS89162.1 - 1.7 8.3 14.3 18 5.1 0.1 5.4 2 2 3 6 6 6 0 Helix-turn-helix domain LIX1 PF14954.6 RUS89163.1 - 8e-135 447.9 0.2 1.1e-134 447.4 0.2 1.2 1 0 0 1 1 1 1 Limb expression 1 TF_AP-2 PF03299.14 RUS89163.1 - 0.0029 17.6 1.0 0.024 14.6 0.2 2.2 2 0 0 2 2 2 1 Transcription factor AP-2 LAP1C PF05609.12 RUS89164.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) zf-CCHC_4 PF14392.6 RUS89164.1 - 1.1 9.0 5.6 0.71 9.7 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.14 RUS89164.1 - 2.9 6.1 14.5 4 5.6 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RUS89164.1 - 3.4 5.8 13.2 4.4 5.4 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RUS89164.1 - 6 6.9 15.9 8.6 6.4 15.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein LAT PF15234.6 RUS89164.1 - 8.9 6.0 9.5 18 5.0 9.5 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 RUS89164.1 - 9.4 5.5 19.2 1.2 8.4 14.2 1.9 2 0 0 2 2 2 0 NOA36 protein Ribosomal_S3Ae PF01015.18 RUS89165.1 - 8.4e-96 319.3 8.4 9.7e-96 319.1 8.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family NLRC4_HD2 PF17776.1 RUS89165.1 - 0.004 17.7 0.1 0.0062 17.1 0.1 1.3 1 0 0 1 1 1 1 NLRC4 helical domain HD2 Abhydro_lipase PF04083.16 RUS89165.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Aldose_epim PF01263.20 RUS89166.1 - 4.8e-46 157.4 0.0 5.4e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ribonuc_red_lgC PF02867.15 RUS89168.1 - 1.8e-189 630.7 0.0 2.2e-189 630.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 RUS89168.1 - 2e-23 82.2 0.0 5.6e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 RUS89168.1 - 2.8e-15 56.6 0.0 7.7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain IF3_C PF00707.22 RUS89169.1 - 2.3e-09 37.1 0.3 4.5e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 RUS89169.1 - 0.00075 19.2 8.1 0.0015 18.3 8.1 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF1902 PF08972.11 RUS89169.1 - 0.0082 16.1 0.7 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1902) SP_C-Propep PF08999.10 RUS89170.1 - 0.18 11.6 0.8 2.8 7.8 0.4 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide SLC3A2_N PF16028.5 RUS89170.1 - 2.5 7.7 5.9 0.23 11.0 0.7 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Exo_endo_phos PF03372.23 RUS89171.1 - 0.0009 18.8 0.1 0.0021 17.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3669 PF12417.8 RUS89171.1 - 0.16 12.2 1.0 2.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger protein tRNA-synt_2 PF00152.20 RUS89172.1 - 3e-44 151.4 0.0 3.6e-27 95.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RUS89172.1 - 2e-07 30.9 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ABC_tran PF00005.27 RUS89173.1 - 1.9e-49 167.7 0.0 6.2e-25 88.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 RUS89173.1 - 9.3e-32 110.5 34.5 3.6e-18 65.8 18.0 3.0 3 0 0 3 3 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 RUS89173.1 - 1.7e-16 61.0 0.0 2.6e-05 24.2 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 RUS89173.1 - 1e-06 29.4 0.0 0.004 17.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 RUS89173.1 - 4.6e-06 26.6 0.0 0.0016 18.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RUS89173.1 - 0.00022 21.8 1.2 0.044 14.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RUS89173.1 - 0.00037 20.4 2.8 0.59 10.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 RUS89173.1 - 0.0011 19.2 0.0 1.6 9.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 RUS89173.1 - 0.0041 17.5 0.1 5.1 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 RUS89173.1 - 0.0048 17.0 1.2 0.26 11.4 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 RUS89173.1 - 0.0082 15.6 0.0 18 4.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS89173.1 - 0.0089 16.3 1.8 2.1 8.6 0.1 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 RUS89173.1 - 0.014 14.7 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 RUS89173.1 - 0.021 14.6 2.7 0.93 9.3 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RUS89173.1 - 0.024 14.3 0.6 0.6 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RUS89173.1 - 0.047 13.4 0.2 11 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RUS89173.1 - 0.2 11.1 2.3 5.3 6.5 0.1 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region FeoB_N PF02421.18 RUS89173.1 - 0.52 9.8 2.2 16 5.0 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B SRP54 PF00448.22 RUS89173.1 - 1.4 8.5 3.2 0.49 10.0 0.4 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PH PF00169.29 RUS89174.1 - 3.6e-12 46.7 0.5 1.7e-11 44.5 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_6 PF15406.6 RUS89174.1 - 2.1e-05 24.8 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain NRIP1_repr_3 PF15689.5 RUS89174.1 - 0.07 13.4 1.2 0.24 11.7 0.2 2.5 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 PH_13 PF16652.5 RUS89174.1 - 0.078 12.8 0.1 0.7 9.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain VWA_2 PF13519.6 RUS89174.1 - 0.41 11.3 2.2 2 9.1 0.1 2.8 3 0 0 3 3 3 0 von Willebrand factor type A domain ABC_membrane PF00664.23 RUS89175.1 - 4.2e-37 128.3 23.5 2e-27 96.5 5.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS89175.1 - 1.3e-13 51.7 0.0 1.6e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter TIP49_C PF17856.1 RUS89175.1 - 0.22 11.7 1.6 4.3 7.5 0.3 2.7 2 0 0 2 2 2 0 TIP49 AAA-lid domain SLAIN PF15301.6 RUS89176.1 - 2.8e-11 43.3 36.4 3.7e-08 33.1 0.4 2.9 2 1 0 2 2 2 2 SLAIN motif-containing family adh_short PF00106.25 RUS89177.1 - 2.8e-60 203.1 1.3 3.3e-60 202.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS89177.1 - 2.3e-40 138.6 1.3 2.9e-40 138.3 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS89177.1 - 3.1e-13 50.0 0.3 4.3e-13 49.6 0.3 1.2 1 0 0 1 1 1 1 KR domain ABC1 PF03109.16 RUS89178.1 - 6.5e-09 36.0 0.1 2.5e-07 30.9 0.0 3.1 3 0 0 3 3 3 1 ABC1 family RIO1 PF01163.22 RUS89178.1 - 0.00033 20.3 0.1 0.00071 19.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family EF-hand_1 PF00036.32 RUS89179.1 - 4e-31 104.2 15.9 5.2e-09 35.0 1.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS89179.1 - 1.2e-28 99.3 10.2 3.7e-14 52.9 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS89179.1 - 1.2e-24 84.1 12.3 4.9e-09 35.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RUS89179.1 - 7.4e-23 80.2 10.7 2.5e-12 46.5 1.4 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 RUS89179.1 - 2e-15 56.9 0.4 2.5e-07 30.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 RUS89179.1 - 1.2e-12 46.7 14.6 8.1e-06 25.1 0.2 4.6 4 1 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 RUS89179.1 - 2.1e-05 24.4 6.9 0.09 12.7 1.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 RUS89179.1 - 0.0008 19.7 2.1 0.38 11.1 0.4 2.5 1 1 0 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 RUS89179.1 - 0.0013 18.6 2.4 0.75 9.6 0.2 2.1 1 1 0 2 2 2 2 SurA N-terminal domain TerB PF05099.13 RUS89179.1 - 0.0023 17.9 2.2 0.013 15.4 0.1 2.5 1 1 2 3 3 3 1 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 RUS89179.1 - 0.0027 18.0 1.1 1.2 9.5 0.3 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region ERAP1_C PF11838.8 RUS89179.1 - 0.0031 17.1 0.1 0.0039 16.8 0.1 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FlgD PF03963.14 RUS89179.1 - 0.0038 17.5 0.1 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region SurA_N_2 PF13623.6 RUS89179.1 - 0.0044 16.9 0.9 1.1 9.1 0.1 2.5 2 1 0 2 2 2 1 SurA N-terminal domain DUF853 PF05872.12 RUS89179.1 - 0.01 14.5 0.3 0.13 10.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 RUS89179.1 - 0.016 16.1 0.4 4 8.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain SUB1_ProdP9 PF18213.1 RUS89179.1 - 0.019 14.8 0.7 0.031 14.1 0.2 1.6 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 Dockerin_1 PF00404.18 RUS89179.1 - 0.028 14.6 2.0 0.45 10.7 0.2 2.6 2 1 1 3 3 3 0 Dockerin type I domain DUF3911 PF13050.6 RUS89179.1 - 0.12 12.5 1.6 1.1 9.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3911) DUF3008 PF11450.8 RUS89179.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) Caleosin PF05042.13 RUS89179.1 - 0.17 11.8 1.0 7.8 6.4 0.0 3.2 1 1 3 4 4 4 0 Caleosin related protein DUF21 PF01595.20 RUS89179.1 - 0.29 10.8 0.8 1.2 8.8 0.2 2.0 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SRI PF08236.11 RUS89179.1 - 0.31 11.2 5.0 2.4 8.4 0.0 3.4 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain SHOCT PF09851.9 RUS89179.1 - 0.37 10.6 0.2 0.37 10.6 0.2 3.4 3 1 0 3 3 3 0 Short C-terminal domain Styelin PF17562.2 RUS89179.1 - 0.73 10.2 4.7 1.1 9.6 2.5 2.4 2 1 1 3 3 2 0 Styelin Homeodomain PF00046.29 RUS89180.1 - 7.1e-24 83.4 3.2 1.2e-23 82.7 3.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS89180.1 - 0.0011 18.8 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Menin PF05053.13 RUS89180.1 - 0.6 8.4 11.5 0.79 8.0 11.5 1.2 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 RUS89180.1 - 8 5.1 12.5 10 4.7 12.5 1.2 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 RUS89181.1 - 0.0044 16.7 8.4 0.0044 16.7 8.4 1.4 2 0 0 2 2 2 1 PPP4R2 TFB6 PF17110.5 RUS89181.1 - 0.0085 15.9 6.4 0.015 15.1 6.4 1.4 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH TFIIA PF03153.13 RUS89181.1 - 0.009 16.0 15.2 0.0092 16.0 15.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RUS89181.1 - 0.073 12.4 11.5 0.091 12.1 11.5 1.3 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 RUS89181.1 - 0.17 10.8 7.7 0.21 10.5 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 RUS89181.1 - 0.26 9.3 36.2 0.36 8.9 36.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS89181.1 - 0.36 9.0 20.9 0.41 8.8 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3295 PF11702.8 RUS89181.1 - 1.2 8.4 14.3 1.6 8.0 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CobT PF06213.12 RUS89181.1 - 8.3 5.7 19.1 0.6 9.4 14.5 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 RUS89181.1 - 9.3 6.1 20.1 21 4.9 20.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-H2C2_5 PF13909.6 RUS89182.1 - 6.3e-13 48.2 63.1 0.00021 21.0 0.1 9.4 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS89182.1 - 3.4e-12 46.2 70.9 0.0039 17.5 0.1 10.6 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS89182.1 - 0.00032 21.3 83.6 0.049 14.5 0.6 9.8 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS89182.1 - 0.0007 19.9 3.5 0.0007 19.9 3.5 10.3 11 0 0 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 RUS89182.1 - 0.0044 17.3 44.5 0.025 14.9 0.2 6.3 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) Vps36-NZF-N PF16988.5 RUS89182.1 - 0.015 14.6 0.5 0.1 12.0 0.1 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_9 PF16293.5 RUS89182.1 - 0.036 13.9 11.5 1.3 8.9 0.1 4.6 3 1 2 5 5 5 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 RUS89182.1 - 0.055 13.3 0.1 0.055 13.3 0.1 5.5 5 2 1 6 6 6 0 GAGA factor DHHC PF01529.20 RUS89183.1 - 2e-36 125.0 15.0 2e-36 125.0 15.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Reticulon PF02453.17 RUS89183.1 - 0.0016 18.5 0.4 0.0016 18.5 0.4 2.3 2 0 0 2 2 2 1 Reticulon DUF4537 PF15057.6 RUS89184.1 - 9.6e-74 245.1 2.0 5.5e-27 94.2 0.5 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4537) VWA_3 PF13768.6 RUS89184.1 - 5.3e-31 107.7 3.7 1.7e-19 70.2 0.0 3.5 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA PF00092.28 RUS89184.1 - 2.2e-11 44.3 0.0 8.6e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 von Willebrand factor type A domain Tudor_3 PF18115.1 RUS89184.1 - 3.5e-10 39.6 4.0 0.003 17.3 0.0 5.2 5 1 1 6 6 6 2 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 RUS89184.1 - 3e-08 33.2 3.0 0.13 12.0 0.0 4.9 5 0 0 5 5 5 2 Jumonji domain-containing protein 2A Tudor domain VWA_2 PF13519.6 RUS89184.1 - 7.4e-08 33.0 0.1 3.2e-05 24.5 0.0 3.6 3 0 0 3 3 3 1 von Willebrand factor type A domain Agenet PF05641.12 RUS89184.1 - 1.3e-05 25.6 1.5 0.16 12.5 0.0 3.9 3 0 0 3 3 3 2 Agenet domain DUF4407 PF14362.6 RUS89184.1 - 0.00069 19.1 2.9 0.0017 17.8 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PCB_OB PF17092.5 RUS89184.1 - 0.0017 19.1 0.2 0.18 12.6 0.0 3.7 3 0 0 3 3 3 1 Penicillin-binding protein OB-like domain 53-BP1_Tudor PF09038.10 RUS89184.1 - 0.14 12.1 0.7 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Tumour suppressor p53-binding protein-1 Tudor SlyX PF04102.12 RUS89184.1 - 0.37 11.4 3.5 3 8.5 3.5 2.7 1 0 0 1 1 1 0 SlyX TMPIT PF07851.13 RUS89184.1 - 4.3 6.5 7.2 11 5.2 7.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein OCIA PF07051.11 RUS89185.1 - 3.7e-27 94.2 0.0 5.3e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) Peroxin-3 PF04882.12 RUS89185.1 - 0.033 13.2 1.4 0.047 12.7 1.4 1.1 1 0 0 1 1 1 0 Peroxin-3 GATase_5 PF13507.6 RUS89186.1 - 5.2e-101 337.1 0.0 7.6e-101 336.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 RUS89186.1 - 3.4e-34 118.2 0.6 2.5e-19 69.9 0.3 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 RUS89186.1 - 2.4e-15 56.5 0.0 4.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 RUS89186.1 - 7.1e-11 42.5 0.0 1.6e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Myelin_PLP PF01275.19 RUS89187.1 - 1.1e-09 38.5 11.1 1.1e-09 38.5 11.1 2.5 1 1 0 2 2 2 1 Myelin proteolipid protein (PLP or lipophilin) EVI2A PF05399.11 RUS89187.1 - 0.015 14.9 5.8 0.057 13.0 0.1 2.4 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Sh_2 PF17512.2 RUS89187.1 - 0.13 12.0 2.7 0.28 11.0 0.3 2.2 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein TFIIA PF03153.13 RUS89187.1 - 0.14 12.1 25.3 0.18 11.7 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 RUS89187.1 - 9.2 4.4 23.8 12 4.0 23.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CotH PF08757.11 RUS89189.1 - 0.015 14.9 0.1 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 CotH kinase protein Trp_repressor PF01371.19 RUS89189.1 - 0.057 13.6 1.0 0.59 10.3 0.3 2.4 1 1 1 2 2 2 0 Trp repressor protein Fzo_mitofusin PF04799.13 RUS89190.1 - 5 6.7 11.2 2.7 7.5 0.3 3.1 3 0 0 3 3 3 0 fzo-like conserved region Peptidase_C78 PF07910.13 RUS89191.1 - 8.1e-49 166.0 0.4 1.3e-48 165.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family C78 DotA PF11388.8 RUS89191.1 - 0.061 13.5 0.4 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Phagosome trafficking protein DotA GAD-like PF08887.11 RUS89191.1 - 0.16 11.8 0.5 0.48 10.2 0.5 1.8 1 0 0 1 1 1 0 GAD-like domain p450 PF00067.22 RUS89192.1 - 1e-98 331.1 0.1 2.9e-98 329.6 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 RUS89193.1 - 2.7e-111 373.0 0.0 6.1e-101 338.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS89193.1 - 5.8e-10 39.4 0.0 1.6e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L31e PF01198.19 RUS89194.1 - 1.6e-44 150.1 0.7 2e-44 149.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 RUS89194.1 - 0.011 15.5 0.1 0.041 13.7 0.0 1.8 1 1 1 2 2 2 0 DNA mismatch endonuclease Vsr PWI PF01480.17 RUS89195.1 - 4.1e-09 36.6 0.0 8.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 RUS89195.1 - 6e-09 35.8 0.0 5.1e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 RUS89195.1 - 0.00011 22.0 0.3 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RUS89195.1 - 0.0039 17.1 0.8 0.0069 16.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF505 PF04458.12 RUS89195.1 - 0.014 13.8 4.7 0.02 13.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) zf_CCCH_4 PF18345.1 RUS89195.1 - 0.045 13.8 0.4 0.077 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc finger domain AAA_2 PF07724.14 RUS89196.1 - 9.3e-32 110.5 1.3 1.7e-31 109.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 RUS89196.1 - 1.7e-09 37.6 0.1 4.5e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Ank PF00023.30 RUS89196.1 - 1.4e-08 34.7 0.6 2.7e-06 27.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat AAA PF00004.29 RUS89196.1 - 1.6e-07 31.8 0.1 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS89196.1 - 2.3e-07 30.9 0.0 9.2e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 RUS89196.1 - 1.3e-06 28.9 0.3 5.9e-06 26.8 0.3 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS89196.1 - 5.1e-06 26.7 0.1 0.00047 20.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89196.1 - 1e-05 25.5 0.3 0.00031 21.0 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS89196.1 - 2.6e-05 24.7 0.2 0.0029 18.2 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sigma54_activat PF00158.26 RUS89196.1 - 2.9e-05 23.8 0.1 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 RUS89196.1 - 6.6e-05 23.4 0.1 0.0062 16.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 RUS89196.1 - 0.00012 21.4 0.1 0.00037 19.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 RUS89196.1 - 0.0011 19.3 0.0 0.0038 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 RUS89196.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_24 PF13479.6 RUS89196.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 RUS89196.1 - 0.0068 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 RUS89196.1 - 0.012 15.5 0.4 0.099 12.5 0.2 2.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RUS89196.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Glucosamine_iso PF01182.20 RUS89197.1 - 1.1e-12 48.3 0.0 2.7e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Nop14 PF04147.12 RUS89198.1 - 3e-06 25.8 21.5 3.3e-06 25.6 21.5 1.2 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 RUS89198.1 - 0.00064 18.0 41.7 0.00089 17.5 41.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi Serinc PF03348.15 RUS89198.1 - 0.027 13.4 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 RUS89198.1 - 0.075 11.8 5.3 0.088 11.6 5.3 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 RUS89198.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.3 1 1 1 2 2 2 0 Connexin LMBR1 PF04791.16 RUS89198.1 - 0.15 10.9 1.0 0.2 10.5 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EOS1 PF12326.8 RUS89198.1 - 0.94 9.4 3.5 14 5.5 3.5 2.1 1 1 0 1 1 1 0 N-glycosylation protein DUF3295 PF11702.8 RUS89198.1 - 1.3 8.3 19.5 1.6 8.0 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SGT1 PF07093.11 RUS89198.1 - 1.4 7.3 20.5 1.9 6.8 20.5 1.2 1 0 0 1 1 1 0 SGT1 protein GRP PF07172.11 RUS89198.1 - 1.6 9.5 27.5 0.54 11.0 17.4 3.1 1 1 1 2 2 2 0 Glycine rich protein family RRN3 PF05327.11 RUS89198.1 - 3.7 6.0 27.5 4.8 5.6 27.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.14 RUS89198.1 - 6.4 7.2 8.2 0.8 10.1 2.7 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 XAP5 PF04921.14 RUS89198.1 - 10 5.9 18.8 20 4.9 18.8 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator TMIE PF16038.5 RUS89199.1 - 0.35 10.8 1.7 3.6 7.5 0.2 2.3 2 0 0 2 2 2 0 TMIE protein 7tm_1 PF00001.21 RUS89200.1 - 4e-73 246.0 10.1 5e-73 245.7 10.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS89200.1 - 1.8e-14 53.7 11.6 2.4e-14 53.4 11.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS89200.1 - 5.1e-07 29.6 13.2 5.1e-07 29.6 13.2 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS89200.1 - 0.019 14.7 9.1 0.087 12.5 6.3 2.3 2 0 0 2 2 2 0 Olfactory receptor DUF2873 PF11395.8 RUS89200.1 - 2.5 8.0 6.0 5 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) CSG2 PF16965.5 RUS89202.1 - 0.059 12.3 0.9 3 6.7 0.2 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator FimA PF16970.5 RUS89203.1 - 0.13 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Type-1 fimbrial protein, A Sulfate_transp PF00916.20 RUS89204.1 - 2e-59 201.3 8.3 3.5e-59 200.5 8.3 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RUS89204.1 - 1.4e-10 40.8 0.0 2.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 RUS89204.1 - 0.037 14.4 8.8 0.052 13.9 6.0 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF4190 PF13828.6 RUS89205.1 - 6.2e-05 22.7 6.4 6.4 6.6 5.5 4.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4190) Trypsin PF00089.26 RUS89206.1 - 1.5e-62 211.3 0.2 2.2e-62 210.8 0.2 1.2 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 RUS89206.1 - 2.6e-09 37.1 12.1 6.1e-09 36.0 12.1 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 RUS89206.1 - 6.8e-08 32.8 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 RUS89206.1 - 1e-05 26.4 0.0 3.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF1986 PF09342.11 RUS89206.1 - 0.047 14.1 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ion_trans PF00520.31 RUS89209.1 - 2.9e-240 793.0 85.0 1.9e-67 227.0 15.1 5.1 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 RUS89209.1 - 2.5e-12 46.2 85.9 1.6e-07 30.3 1.6 10.6 7 4 2 11 11 11 9 Polycystin cation channel Pex14_N PF04695.13 RUS89209.1 - 0.0042 17.8 2.9 0.055 14.1 0.2 3.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Vpu PF00558.19 RUS89209.1 - 0.028 14.2 0.2 0.68 9.7 0.2 3.1 2 0 0 2 2 2 0 Vpu protein DUF4834 PF16118.5 RUS89209.1 - 0.34 11.9 0.0 0.34 11.9 0.0 6.8 6 1 0 6 6 6 0 Domain of unknown function (DUF4834) Insulin_TMD PF17870.1 RUS89209.1 - 2.6 8.2 12.7 0.62 10.2 0.1 4.7 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Jak1_Phl PF17887.1 RUS89209.1 - 9.5 6.2 7.7 0.35 10.8 1.1 1.9 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Penicillinase_R PF03965.16 RUS89210.1 - 5.4 7.4 13.4 4.3 7.7 1.3 3.5 2 1 0 3 3 3 0 Penicillinase repressor RNase_T PF00929.24 RUS89212.1 - 1.4e-25 90.8 0.0 2.1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 RUS89212.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like DUF1118 PF06549.12 RUS89213.1 - 1.4e-11 44.7 0.7 0.0014 19.0 0.0 4.1 2 1 3 5 5 5 5 Protein of unknown function (DUF1118) Dimerisation PF08100.11 RUS89213.1 - 0.014 15.4 0.2 78 3.4 0.0 5.4 5 1 1 6 6 6 0 Dimerisation domain PIN_5 PF08745.11 RUS89213.1 - 0.67 9.3 3.6 2.3 7.6 0.3 2.8 2 1 0 2 2 2 0 PINc domain ribonuclease Spt20 PF12090.8 RUS89214.1 - 0.00034 20.3 26.4 0.029 14.0 8.8 2.3 2 0 0 2 2 2 2 Spt20 family DUF2052 PF09747.9 RUS89214.1 - 0.00034 20.8 2.3 0.14 12.3 0.1 2.1 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) EIIBC-GUT_N PF03612.14 RUS89214.1 - 0.04 13.7 5.0 0.4 10.4 0.1 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Plasmodium_Vir PF05795.11 RUS89214.1 - 0.18 11.2 9.0 0.62 9.4 0.1 2.2 1 1 1 2 2 2 0 Plasmodium vivax Vir protein FAM76 PF16046.5 RUS89214.1 - 0.19 11.0 11.8 0.24 10.7 3.1 2.1 2 0 0 2 2 2 0 FAM76 protein DUF4770 PF15994.5 RUS89214.1 - 0.31 11.3 9.7 1.2 9.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MecA PF05389.12 RUS89214.1 - 0.58 9.7 5.5 2.9 7.4 0.3 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Suf PF05843.14 RUS89214.1 - 0.67 9.9 22.4 1.7 8.5 2.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF719 PF05334.13 RUS89214.1 - 0.72 10.0 6.6 9.3 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TERB2 PF15101.6 RUS89214.1 - 0.75 9.8 18.4 2.1 8.3 7.2 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ATG22 PF11700.8 RUS89214.1 - 0.91 8.1 6.5 0.39 9.3 0.2 2.0 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like ALMT PF11744.8 RUS89214.1 - 1.8 7.3 5.8 2.9 6.6 0.6 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Zip PF02535.22 RUS89214.1 - 1.9 7.6 14.2 0.69 9.1 4.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_pol_Rbc25 PF08292.12 RUS89214.1 - 5.2 7.3 10.4 6.5 7.0 1.7 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Rpp20 PF12328.8 RUS89214.1 - 5.7 6.9 9.2 3.7 7.5 0.5 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P DUF4834 PF16118.5 RUS89214.1 - 6.4 7.8 15.0 8.9 7.4 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF883 PF05957.13 RUS89214.1 - 6.9 7.3 7.5 0.25 12.0 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Homeodomain PF00046.29 RUS89215.1 - 2.7e-21 75.2 1.8 4.3e-21 74.5 1.8 1.3 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 RUS89215.1 - 0.016 15.7 0.4 0.016 15.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 RUS89215.1 - 0.03 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 RUS89215.1 - 0.14 11.6 0.5 0.34 10.4 0.1 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 RUS89215.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT zf-CCCH_2 PF14608.6 RUS89218.1 - 1.3e-13 50.8 54.9 1.3e-06 28.6 2.6 5.4 4 1 1 5 5 5 4 RNA-binding, Nab2-type zinc finger PWI PF01480.17 RUS89218.1 - 0.00053 20.2 0.2 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 PWI domain zf-CCCH_4 PF18044.1 RUS89218.1 - 0.012 15.4 3.8 0.012 15.4 3.8 4.4 4 1 0 4 4 4 0 CCCH-type zinc finger zf-CCCH PF00642.24 RUS89218.1 - 0.029 14.3 0.5 0.029 14.3 0.5 5.1 3 2 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS89218.1 - 0.031 14.3 0.8 0.031 14.3 0.8 5.5 6 1 1 7 7 7 0 Zinc finger domain Iso_dh PF00180.20 RUS89219.1 - 1.3e-78 264.6 0.0 1.7e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ART-PolyVal PF18760.1 RUS89219.1 - 0.021 15.8 0.2 0.04 14.9 0.2 1.4 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins CLASP_N PF12348.8 RUS89220.1 - 2.3e-32 112.4 7.5 2.2e-08 33.9 0.0 6.0 6 0 0 6 6 6 5 CLASP N terminal HEAT PF02985.22 RUS89220.1 - 2.9e-16 58.2 1.6 0.018 15.3 0.1 9.9 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 RUS89220.1 - 4.4e-11 43.0 0.1 0.38 11.2 0.0 8.5 5 2 3 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 RUS89220.1 - 7.7e-07 29.6 2.0 8.3 7.1 0.0 7.5 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RUS89220.1 - 0.00051 20.1 18.5 11 6.0 0.0 9.3 8 3 4 12 12 12 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS89220.1 - 0.0015 19.0 1.8 17 6.0 0.1 6.5 7 0 0 7 7 7 1 HEAT-like repeat Tti2 PF10521.9 RUS89220.1 - 0.0029 17.2 0.6 3.7 7.0 0.0 4.4 4 0 0 4 4 4 1 Tti2 family TraI_2_C PF07515.11 RUS89220.1 - 0.077 13.0 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term ESAG1 PF03238.13 RUS89220.1 - 0.11 11.9 0.2 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 ESAG protein RAD51_interact PF15696.5 RUS89221.1 - 2.8e-12 46.5 5.5 2.8e-12 46.5 5.5 2.9 2 0 0 2 2 2 1 RAD51 interacting motif Ldl_recept_b PF00058.17 RUS89222.1 - 5.7e-157 510.0 59.9 1.2e-12 48.1 0.2 20.6 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 RUS89222.1 - 6.7e-64 211.8 119.2 5e-12 45.8 10.7 8.4 7 0 0 7 7 7 7 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 RUS89222.1 - 1.5e-52 175.6 119.9 5.2e-12 45.8 7.1 8.9 8 1 0 8 8 6 6 Coagulation Factor Xa inhibitory site SGL PF08450.12 RUS89222.1 - 7.8e-15 55.1 17.0 0.0076 15.9 2.7 9.6 5 3 4 9 9 9 5 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 RUS89222.1 - 3.1e-14 52.6 31.8 6.8e-06 25.9 0.2 7.0 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS89222.1 - 1.7e-07 31.3 8.1 1.7e-07 31.3 8.1 11.1 8 3 3 11 11 5 1 Calcium-binding EGF domain DUF5050 PF16472.5 RUS89222.1 - 8.3e-07 28.5 0.0 0.12 11.6 0.0 4.4 4 2 0 4 4 4 2 Domain of unknown function (DUF5050) NHL PF01436.21 RUS89222.1 - 0.00036 20.4 3.8 11 6.3 0.0 7.0 7 0 0 7 7 7 1 NHL repeat RCR PF12273.8 RUS89222.1 - 0.0018 18.9 0.0 0.0033 18.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Arylesterase PF01731.20 RUS89222.1 - 0.028 14.6 0.0 17 5.7 0.0 4.9 6 0 0 6 6 6 0 Arylesterase SL4P PF17618.2 RUS89222.1 - 0.25 11.4 15.3 19 5.4 0.0 8.3 10 0 0 10 10 10 0 Uncharacterized Strongylid L4 protein DUF1242 PF06842.12 RUS89223.1 - 3.1e-19 68.5 3.5 4.5e-19 68.0 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Somatomedin_B PF01033.17 RUS89224.1 - 2e-05 24.9 7.7 2e-05 24.9 7.7 2.3 2 0 0 2 2 2 1 Somatomedin B domain 7tm_1 PF00001.21 RUS89225.1 - 3e-11 43.2 0.3 7.5e-11 41.8 0.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM190 PF15431.6 RUS89225.1 - 0.31 11.2 3.0 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Transmembrane protein 190 IPP-2 PF04979.14 RUS89226.1 - 5.5e-27 95.1 5.8 4.5e-19 69.5 0.3 2.1 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2045 PF09741.9 RUS89227.1 - 1.8e-89 299.1 0.0 2.3e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) DNA_binding_1 PF01035.20 RUS89227.1 - 0.094 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain VHL PF01847.16 RUS89228.1 - 1.3e-06 28.2 0.1 1.8e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 VHL beta domain VHL_C PF17211.3 RUS89228.1 - 0.0011 18.9 0.8 0.0018 18.3 0.8 1.3 1 0 0 1 1 1 1 VHL box domain DUF192 PF02643.15 RUS89228.1 - 0.083 13.0 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1430 GSP_synth PF03738.14 RUS89228.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp PTCB-BRCT PF12738.7 RUS89229.1 - 2.2e-51 171.6 9.0 5.7e-20 71.0 0.2 5.9 6 0 0 6 6 6 5 twin BRCT domain BRCT PF00533.26 RUS89229.1 - 4.5e-48 161.5 2.6 4.4e-12 46.2 0.0 6.4 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RUS89229.1 - 3e-35 120.5 1.9 1.5e-07 31.7 0.1 6.2 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RUS89229.1 - 4.5e-18 65.0 0.0 2e-11 43.7 0.0 4.3 4 0 0 4 4 4 3 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 RUS89229.1 - 1.2e-08 35.2 7.7 0.0061 16.8 0.1 4.6 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 RUS89229.1 - 4.2e-06 26.8 2.2 0.73 9.9 0.1 4.8 6 0 0 6 6 6 2 BRCA1 C Terminus (BRCT) domain dsrm PF00035.26 RUS89230.1 - 1.8e-17 63.8 1.2 7.1e-11 42.6 0.2 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif TFIIF_alpha PF05793.12 RUS89230.1 - 0.75 8.3 25.6 1.1 7.7 25.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) rve PF00665.26 RUS89231.1 - 5.2e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain 7tm_1 PF00001.21 RUS89232.1 - 2.1e-10 40.4 8.5 3e-10 39.9 8.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS89232.1 - 1e-07 31.5 13.4 4.9e-07 29.3 13.4 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS89232.1 - 0.00059 19.5 14.4 0.00059 19.5 14.4 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Lipase PF00151.19 RUS89233.1 - 1.1e-73 248.5 0.0 1.4e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 Lipase CNTF PF01110.17 RUS89233.1 - 0.07 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor Guanylate_kin PF00625.21 RUS89234.1 - 1.7e-45 154.9 0.4 7.7e-45 152.8 0.4 1.9 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.16 RUS89234.1 - 5e-12 45.4 3.8 1.7e-09 37.2 0.5 2.8 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 RUS89234.1 - 9.3e-08 32.3 0.6 1.9e-07 31.3 0.6 1.5 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 RUS89234.1 - 1.3e-06 27.9 0.0 3.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 RUS89234.1 - 0.00011 21.9 0.1 0.00049 19.9 0.1 2.2 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 RUS89234.1 - 0.0003 20.4 0.0 0.00075 19.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS89234.1 - 0.0022 17.8 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RsgA_GTPase PF03193.16 RUS89234.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PDZ_2 PF13180.6 RUS89234.1 - 0.021 15.1 0.8 0.048 14.0 0.2 1.9 2 0 0 2 2 2 0 PDZ domain Rrp44_S1 PF17215.3 RUS89234.1 - 0.54 10.2 3.7 9.4 6.3 0.4 3.1 3 0 0 3 3 3 0 S1 domain MFS_1 PF07690.16 RUS89235.1 - 2.5e-18 66.1 45.7 3.9e-17 62.2 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 RUS89235.1 - 0.24 9.3 2.4 0.15 10.0 0.3 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CPP1-like PF11833.8 RUS89235.1 - 0.65 9.6 5.6 2.3 7.9 5.6 1.9 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF647 PF04884.14 RUS89235.1 - 1.2 8.7 9.1 0.24 11.0 3.1 2.3 2 0 0 2 2 2 0 Vitamin B6 photo-protection and homoeostasis Trp_oprn_chp PF09534.10 RUS89235.1 - 1.3 8.8 4.4 0.33 10.7 0.5 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SNARE_assoc PF09335.11 RUS89235.1 - 2.1 8.8 15.5 0.71 10.4 0.1 4.2 3 2 2 5 5 5 0 SNARE associated Golgi protein DSL PF01414.19 RUS89236.1 - 0.02 15.2 10.7 0.02 15.2 10.7 3.7 3 0 0 3 3 3 0 Delta serrate ligand Piwi PF02171.17 RUS89237.1 - 3.2e-88 295.9 0.6 4.7e-88 295.3 0.6 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RUS89237.1 - 6.2e-13 48.7 0.0 2.6e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RUS89237.1 - 0.00011 22.9 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute Pex2_Pex12 PF04757.14 RUS89238.1 - 9.1e-41 139.9 6.9 1.1e-40 139.6 6.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RUS89238.1 - 0.0011 18.7 5.1 0.0021 17.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS89238.1 - 0.019 15.3 5.0 0.047 14.0 5.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 RUS89238.1 - 0.024 14.5 6.4 0.025 14.4 4.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F1F0-ATPsyn_F PF10791.9 RUS89238.1 - 0.11 13.0 0.5 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi TniQ PF06527.11 RUS89238.1 - 0.12 13.1 2.1 0.16 12.7 1.0 2.0 1 1 1 2 2 2 0 TniQ zf-C3HC4 PF00097.25 RUS89238.1 - 0.65 9.9 8.6 4.4 7.2 8.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF953 PF06110.11 RUS89239.1 - 4.8e-42 142.3 0.3 6.2e-42 142.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 RUS89239.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin adh_short_C2 PF13561.6 RUS89240.1 - 2.5e-48 164.7 0.0 3.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS89240.1 - 8.8e-41 139.5 0.1 1.2e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS89240.1 - 2.6e-06 27.5 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 RUS89240.1 - 0.00088 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RUS89240.1 - 0.0011 19.6 0.2 0.004 17.7 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 RUS89240.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3342 PF11822.8 RUS89242.1 - 1.2e-37 128.0 1.7 3e-37 126.7 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 RUS89242.1 - 0.003 17.8 0.2 0.0054 17.0 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Myb_DNA-binding PF00249.31 RUS89242.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain OrfB_Zn_ribbon PF07282.11 RUS89242.1 - 0.2 11.6 1.8 0.67 9.9 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain 7tm_1 PF00001.21 RUS89243.1 - 2.3e-56 191.1 12.4 3.6e-56 190.4 12.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS89243.1 - 4.6e-07 29.7 12.4 5.6e-07 29.5 11.1 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS89243.1 - 0.00036 20.0 6.0 0.00036 20.0 6.0 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS89243.1 - 0.0078 16.0 5.4 0.0078 16.0 5.4 2.4 2 0 0 2 2 2 2 Olfactory receptor Git3 PF11710.8 RUS89243.1 - 8.3 6.1 11.0 9.4 6.0 9.1 2.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Kelch_4 PF13418.6 RUS89245.1 - 3.4e-21 75.0 14.7 2.7e-09 36.9 0.8 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS89245.1 - 1.2e-19 70.1 19.0 2.1e-08 34.3 0.3 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 RUS89245.1 - 3.4e-19 68.2 7.4 7.4e-07 28.6 0.2 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 RUS89245.1 - 3.3e-16 58.9 7.8 3.2e-06 27.2 0.3 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 RUS89245.1 - 2.3e-15 56.2 10.1 0.00015 21.7 0.4 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 RUS89245.1 - 4.3e-14 51.8 12.1 0.0027 17.6 0.2 6.3 7 0 0 7 7 7 3 Kelch motif F-box-like PF12937.7 RUS89245.1 - 1.7e-06 27.8 0.1 6.3e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS89245.1 - 2e-05 24.3 0.3 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 RUS89245.1 - 0.025 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 F-box MogR_DNAbind PF12181.8 RUS89245.1 - 0.062 13.2 0.9 0.13 12.2 0.4 1.7 2 0 0 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) UQ_con PF00179.26 RUS89246.1 - 2.7e-19 69.2 0.0 4.4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GATase PF00117.28 RUS89247.1 - 4.4e-37 127.7 0.0 8.8e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 RUS89247.1 - 1.9e-17 63.1 0.0 9e-10 38.5 0.0 2.8 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 RUS89247.1 - 6.6e-11 41.8 0.0 8e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 RUS89247.1 - 2.3e-10 40.6 0.0 4.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 RUS89247.1 - 1.5e-06 27.9 0.0 3.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 RUS89247.1 - 5.2e-05 22.2 0.1 0.00043 19.2 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 RUS89247.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 RUS89247.1 - 0.0017 18.0 0.1 0.0057 16.3 0.1 2.0 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 RUS89247.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 RUS89247.1 - 0.007 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 PP-loop family GATase_3 PF07685.14 RUS89247.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PAPS_reduct PF01507.19 RUS89247.1 - 0.02 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family POTRA_3 PF17287.2 RUS89247.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 POTRA domain Lipocalin_7 PF14651.6 RUS89248.1 - 0.00042 20.3 0.4 0.00065 19.6 0.4 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family MFS_1 PF07690.16 RUS89249.1 - 5.5e-21 74.9 39.5 2.8e-18 66.0 27.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS89249.1 - 1.2 7.9 25.5 0.39 9.5 16.6 3.3 1 1 2 3 3 3 0 MFS_1 like family NicO PF03824.16 RUS89250.1 - 0.085 12.2 2.0 2.8 7.2 0.4 2.4 2 0 0 2 2 2 0 High-affinity nickel-transport protein EMP24_GP25L PF01105.24 RUS89251.1 - 3.7e-19 69.4 1.2 3.7e-19 69.4 1.2 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Tubulin_3 PF14881.6 RUS89251.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin domain RhoGAP PF00620.27 RUS89251.1 - 0.19 11.5 0.6 0.34 10.7 0.3 1.5 2 0 0 2 2 2 0 RhoGAP domain ANF_receptor PF01094.28 RUS89252.1 - 4.7e-76 256.2 0.0 8.5e-76 255.3 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 RUS89252.1 - 1.3e-58 198.5 25.4 2e-58 197.9 25.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 RUS89252.1 - 2e-08 34.3 0.0 1.7e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein NCD3G PF07562.14 RUS89252.1 - 0.00014 21.7 15.7 0.00034 20.5 15.7 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR dCMP_cyt_deam_1 PF00383.23 RUS89253.1 - 1.6e-15 56.8 0.3 2.1e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 RUS89253.1 - 3.3e-15 56.5 0.8 6.7e-14 52.2 0.3 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 RUS89253.1 - 0.013 15.1 3.2 0.093 12.3 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases DNA_pol_phi PF04931.13 RUS89255.1 - 2.1e-62 211.3 34.0 2.1e-62 211.3 34.0 2.3 2 1 0 2 2 2 2 DNA polymerase phi INTS5_N PF14837.6 RUS89255.1 - 0.081 12.5 1.7 0.11 12.1 0.5 1.8 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus FANCI_S2 PF14676.6 RUS89255.1 - 0.19 12.1 3.4 0.84 9.9 0.4 3.0 2 1 0 2 2 2 0 FANCI solenoid 2 DUF3530 PF12048.8 RUS89255.1 - 8.2 5.7 7.8 10 5.4 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) TFIIA PF03153.13 RUS89255.1 - 8.9 6.2 20.2 0.66 9.9 14.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NUDIX_4 PF14815.6 RUS89256.1 - 1.8e-20 73.0 0.2 4.9e-20 71.6 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain HhH-GPD PF00730.25 RUS89256.1 - 3.2e-18 66.2 0.0 8.6e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RUS89256.1 - 2e-08 33.7 0.1 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 RUS89256.1 - 0.0086 16.4 5.2 0.0086 16.4 5.2 2.3 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III Whib PF02467.16 RUS89256.1 - 0.33 11.6 2.6 0.92 10.2 2.6 1.9 1 0 0 1 1 1 0 Transcription factor WhiB fn3 PF00041.21 RUS89257.1 - 1e-26 93.1 1.2 9.1e-09 35.6 0.1 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 RUS89257.1 - 1.4e-09 38.4 9.7 0.0053 17.3 0.0 4.7 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 RUS89257.1 - 1.8e-07 31.2 6.2 0.11 12.6 0.1 4.8 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 RUS89257.1 - 1.1e-06 28.6 0.6 0.78 9.8 0.0 4.6 3 2 2 5 5 5 3 Immunoglobulin I-set domain V-set PF07686.17 RUS89257.1 - 9.3e-06 25.8 0.4 0.36 11.0 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin V-set domain BDV_P10 PF06515.11 RUS89257.1 - 3.7 7.7 9.7 99 3.1 9.0 2.4 2 0 0 2 2 2 0 Borna disease virus P10 protein fn3 PF00041.21 RUS89258.1 - 9e-13 48.4 22.2 0.0023 18.2 0.0 7.8 6 1 1 7 7 7 4 Fibronectin type III domain Ig_3 PF13927.6 RUS89258.1 - 4.5e-07 30.4 0.0 4.5e-07 30.4 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RUS89258.1 - 2.5e-06 27.4 0.0 2.5e-06 27.4 0.0 4.8 5 1 1 6 6 6 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS89258.1 - 3.2e-06 27.4 0.2 6.2e-05 23.3 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS89258.1 - 0.0028 18.2 0.4 0.01 16.4 0.2 8.1 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 RUS89258.1 - 0.013 15.6 0.7 0.08 13.0 0.0 2.8 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 RUS89258.1 - 0.013 15.8 5.7 8.4 6.8 0.0 5.4 4 1 2 6 6 6 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 RUS89259.1 - 1.9e-05 24.9 0.1 0.31 11.4 0.0 3.2 3 0 0 3 3 3 2 Fibronectin type III domain NMT1 PF09084.11 RUS89259.1 - 0.055 13.4 0.8 0.1 12.6 0.8 1.4 1 0 0 1 1 1 0 NMT1/THI5 like ZoocinA_TRD PF16775.5 RUS89259.1 - 0.083 13.0 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Target recognition domain of lytic exoenzyme fn3 PF00041.21 RUS89260.1 - 5.5e-17 61.9 0.5 2.3e-05 24.6 0.0 4.7 4 0 0 4 4 4 3 Fibronectin type III domain Ig_3 PF13927.6 RUS89260.1 - 1.3e-11 44.9 0.1 6e-07 30.0 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 RUS89260.1 - 8e-10 38.7 0.3 8.7e-05 22.5 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS89260.1 - 1.4e-09 38.1 0.0 6.5e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS89260.1 - 0.00021 21.3 0.0 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 RUS89260.1 - 0.0027 17.9 0.0 0.21 11.8 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 RUS89260.1 - 0.0031 17.7 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 RUS89260.1 - 0.053 13.8 0.0 20 5.6 0.0 2.5 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 RUS89261.1 - 2.3e-06 27.9 0.5 0.14 12.5 0.0 3.1 2 0 0 2 2 2 2 Fibronectin type III domain CCDC71L PF15374.6 RUS89261.1 - 0.077 12.3 3.1 0.11 11.8 3.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L GREB1 PF15782.5 RUS89261.1 - 0.14 9.3 19.7 0.18 8.9 19.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM196 PF15265.6 RUS89261.1 - 0.15 11.5 21.1 0.21 11.0 21.1 1.2 1 0 0 1 1 1 0 FAM196 family CAC1F_C PF16885.5 RUS89261.1 - 4.8 6.7 20.9 6.6 6.3 20.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Macoilin PF09726.9 RUS89261.1 - 6.4 5.2 25.0 8.1 4.9 25.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3046 PF11248.8 RUS89262.1 - 3.5 8.1 10.3 2.2 8.7 1.8 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3046) fn3 PF00041.21 RUS89263.1 - 2e-09 37.6 2.0 0.0057 17.0 0.0 4.1 4 0 0 4 4 4 2 Fibronectin type III domain V-set PF07686.17 RUS89263.1 - 0.0019 18.3 0.2 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 RUS89263.1 - 0.0028 17.7 1.6 0.0037 17.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 RUS89263.1 - 0.0065 16.6 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain IL6Ra-bind PF09240.10 RUS89263.1 - 0.021 15.3 1.4 0.057 13.9 0.5 2.3 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Izumo-Ig PF16706.5 RUS89263.1 - 0.03 14.4 0.0 0.099 12.7 0.0 1.9 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 RUS89263.1 - 0.067 13.8 0.0 0.067 13.8 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin domain SARAF PF06682.12 RUS89265.1 - 1e-93 314.7 2.0 1.2e-93 314.4 2.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 RUS89265.1 - 0.079 13.4 1.3 0.46 10.9 2.1 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 KcnmB2_inactiv PF09303.10 RUS89265.1 - 3.5 7.5 6.9 6.1 6.7 4.0 2.7 2 0 0 2 2 2 0 KCNMB2, ball and chain domain SNF PF00209.18 RUS89266.1 - 3.3e-26 92.1 8.8 3.9e-26 91.8 8.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LMBR1 PF04791.16 RUS89266.1 - 0.0026 16.8 0.1 0.0029 16.6 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Yip1 PF04893.17 RUS89266.1 - 0.076 12.7 2.7 0.1 12.3 2.7 1.1 1 0 0 1 1 1 0 Yip1 domain SNF PF00209.18 RUS89267.1 - 3.1e-210 699.3 37.9 3.7e-210 699.1 37.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ThrE PF06738.12 RUS89267.1 - 0.07 12.5 3.8 2 7.8 0.2 2.7 3 0 0 3 3 3 0 Putative threonine/serine exporter UBN_AB PF14075.6 RUS89269.1 - 4.9e-63 212.7 7.5 8e-63 212.0 7.5 1.3 1 0 0 1 1 1 1 Ubinuclein conserved middle domain Cnd1_N PF12922.7 RUS89269.1 - 0.16 11.8 1.5 0.41 10.5 1.5 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Vfa1 PF08432.10 RUS89269.1 - 9.3 6.5 13.3 0.8 10.0 7.9 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RmlD_sub_bind PF04321.17 RUS89271.1 - 6.7e-60 202.6 0.0 8.1e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 RUS89271.1 - 9.4e-21 74.4 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS89271.1 - 7.9e-13 48.5 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RUS89271.1 - 5.8e-12 45.4 0.4 3.9e-10 39.3 0.1 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RUS89271.1 - 5.3e-08 32.3 0.0 1.9e-06 27.2 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 RUS89271.1 - 6.9e-07 28.6 0.0 2.9e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 RUS89271.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Neur_chan_LBD PF02931.23 RUS89273.1 - 2.5e-40 138.2 0.0 6.3e-38 130.4 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS89273.1 - 2.3e-27 96.6 5.8 1.3e-25 90.8 2.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region ASC PF00858.24 RUS89275.1 - 2.3e-77 260.9 0.1 2.7e-77 260.6 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Vps23_core PF09454.10 RUS89275.1 - 0.19 11.7 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Vps23 core domain ASC PF00858.24 RUS89276.1 - 4.2e-70 236.9 1.9 5.5e-70 236.5 1.9 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS89277.1 - 1.1e-60 205.8 3.0 1.7e-60 205.2 3.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 RUS89278.1 - 2.2e-70 237.9 3.3 2.5e-70 237.7 3.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 7tm_1 PF00001.21 RUS89282.1 - 1.3e-28 100.1 11.9 1.5e-28 99.8 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS89282.1 - 0.0013 18.1 16.3 0.01 15.1 0.2 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2371 PF10177.9 RUS89282.1 - 0.12 12.5 0.4 0.23 11.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) LRR_6 PF13516.6 RUS89283.1 - 1e-22 78.2 8.6 0.00021 21.1 0.1 7.6 7 0 0 7 7 7 5 Leucine Rich repeat EF-hand_1 PF00036.32 RUS89283.1 - 4.6e-08 32.1 2.7 0.0022 17.4 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS89283.1 - 3.6e-07 29.6 1.6 0.0078 16.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain LRR_1 PF00560.33 RUS89283.1 - 1.2e-06 28.2 0.0 3.9 8.4 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat EF-hand_7 PF13499.6 RUS89283.1 - 1.3e-06 28.8 1.2 1.2e-05 25.7 1.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS89283.1 - 3.4e-06 26.3 3.0 0.0059 16.0 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RUS89283.1 - 7.1e-06 25.8 0.3 3.3e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair LRR_8 PF13855.6 RUS89283.1 - 0.0065 16.2 1.1 8.3 6.3 0.1 4.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 RUS89283.1 - 0.05 14.1 5.2 1.8 9.1 0.0 4.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Cadherin PF00028.17 RUS89284.1 - 2e-84 278.2 9.5 1.2e-19 70.6 0.6 8.5 8 0 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 RUS89284.1 - 3.3e-07 30.3 9.6 0.057 13.4 0.0 6.1 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 RUS89284.1 - 1.4e-06 28.1 0.6 5.8e-05 22.8 0.1 3.5 3 0 0 3 3 3 1 Cadherin-like SusE PF14292.6 RUS89284.1 - 0.028 14.7 4.7 4.5 7.5 0.0 4.1 4 0 0 4 4 4 0 SusE outer membrane protein Cadherin_C_2 PF16492.5 RUS89284.1 - 0.069 13.9 0.0 0.38 11.5 0.0 2.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RasGAP_C PF03836.15 RUS89286.1 - 0.04 14.1 0.6 0.088 13.0 0.6 1.5 1 0 0 1 1 1 0 RasGAP C-terminus MIEAP PF16026.5 RUS89287.1 - 7.2e-52 176.5 2.0 7.9e-52 176.4 0.0 1.9 2 0 0 2 2 2 1 Mitochondria-eating protein Golgin_A5 PF09787.9 RUS89287.1 - 0.0025 17.3 4.3 0.0044 16.5 4.3 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 TPD52 PF04201.15 RUS89287.1 - 0.012 15.2 0.9 0.012 15.2 0.9 1.7 2 0 0 2 2 2 0 Tumour protein D52 family Snapin_Pallidin PF14712.6 RUS89287.1 - 0.022 15.2 7.5 0.038 14.4 4.6 2.4 2 0 0 2 2 2 0 Snapin/Pallidin UPF0242 PF06785.11 RUS89287.1 - 0.049 13.7 5.5 0.13 12.4 5.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LCD1 PF09798.9 RUS89287.1 - 0.064 11.8 3.3 0.091 11.3 3.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FlaC_arch PF05377.11 RUS89287.1 - 0.067 13.6 0.9 0.067 13.6 0.9 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec3_C_2 PF15278.6 RUS89287.1 - 0.11 12.9 0.6 0.27 11.6 0.6 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit PRKG1_interact PF15898.5 RUS89287.1 - 0.18 12.7 8.6 0.77 10.7 8.6 2.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Retrotrans_gag PF03732.17 RUS89287.1 - 0.19 12.0 1.8 0.54 10.6 0.3 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Mitofilin PF09731.9 RUS89287.1 - 0.25 10.1 9.9 0.38 9.6 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Bap31_Bap29_C PF18035.1 RUS89287.1 - 0.59 10.2 6.2 2.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fib_alpha PF08702.10 RUS89287.1 - 0.85 9.8 5.1 2.3 8.4 5.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RUS89287.1 - 1.1 8.1 12.2 0.71 8.7 7.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 RUS89287.1 - 4.8 7.5 7.5 4.8 7.5 2.8 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF641 PF04859.12 RUS89287.1 - 7.3 6.9 8.2 7 7.0 2.5 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Neur_chan_LBD PF02931.23 RUS89288.1 - 1.6e-27 96.4 0.2 2e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Lipocalin_4 PF13648.6 RUS89288.1 - 0.0083 17.1 0.5 0.017 16.1 0.5 1.5 1 0 0 1 1 1 1 Lipocalin-like domain Neur_chan_LBD PF02931.23 RUS89289.1 - 1.8e-19 70.0 0.0 2.4e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain E1_DerP2_DerF2 PF02221.15 RUS89290.1 - 5.2e-15 56.1 2.9 6.7e-15 55.7 2.9 1.1 1 0 0 1 1 1 1 ML domain Corona_NS2A PF05213.12 RUS89290.1 - 0.085 12.2 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein MFS_1 PF07690.16 RUS89292.1 - 2.8e-12 46.2 2.4 4e-12 45.7 2.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS89294.1 - 0.00075 18.5 0.5 0.00075 18.5 0.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter BRCA-2_helical PF09169.10 RUS89297.1 - 3.7e-48 163.7 0.0 9.9e-48 162.3 0.0 1.7 1 0 0 1 1 1 1 BRCA2, helical BRCA-2_OB1 PF09103.10 RUS89297.1 - 8.6e-35 119.4 0.0 2.1e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.10 RUS89297.1 - 7.9e-11 42.0 4.1 1.6e-10 41.0 4.1 1.6 1 0 0 1 1 1 1 Tower BRCA-2_OB3 PF09104.10 RUS89297.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Exonuc_VII_L PF02601.15 RUS89298.1 - 0.18 11.3 0.0 0.18 11.3 0.0 5.9 5 2 0 5 5 5 0 Exonuclease VII, large subunit Lectin_C PF00059.21 RUS89299.1 - 4.6e-21 75.6 0.0 1.5e-08 35.3 0.0 3.5 3 0 0 3 3 3 3 Lectin C-type domain WSC PF01822.19 RUS89299.1 - 2e-14 53.6 4.6 2e-14 53.6 4.6 2.5 3 0 0 3 3 3 1 WSC domain CBM_14 PF01607.24 RUS89300.1 - 2.3e-81 267.8 129.1 9.2e-12 44.9 3.0 10.4 10 0 0 10 10 10 10 Chitin binding Peritrophin-A domain SepZ PF06066.11 RUS89300.1 - 0.00045 20.4 0.0 1.2 9.4 0.0 3.6 1 1 2 3 3 3 1 SepZ CAP_GLY PF01302.25 RUS89300.1 - 0.0013 18.7 8.3 25 5.0 0.0 6.3 6 1 1 7 7 7 2 CAP-Gly domain MM_CoA_mutase PF01642.22 RUS89300.1 - 0.0023 16.5 1.4 7.6 5.0 0.0 3.1 1 1 2 3 3 3 3 Methylmalonyl-CoA mutase DASH_Hsk3 PF08227.11 RUS89300.1 - 0.038 14.4 9.9 15 6.1 0.3 3.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Pkinase_Tyr PF07714.17 RUS89301.1 - 8.8e-80 267.7 0.0 2.3e-79 266.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89301.1 - 4.7e-37 127.8 0.0 2.1e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Lectin_C PF00059.21 RUS89301.1 - 8.3e-14 52.2 0.4 2.1e-13 50.9 0.4 1.7 1 0 0 1 1 1 1 Lectin C-type domain APH PF01636.23 RUS89301.1 - 0.0088 16.0 0.3 0.034 14.0 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS89301.1 - 0.097 11.6 0.1 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Laminin_EGF PF00053.24 RUS89303.1 - 2.1e-49 165.4 163.9 8.1e-11 41.9 15.7 9.9 10 1 0 10 10 10 8 Laminin EGF domain Laminin_B PF00052.18 RUS89303.1 - 1.6e-12 47.4 0.0 7.5e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_EGF PF00053.24 RUS89304.1 - 1.6e-45 153.0 140.8 9.6e-10 38.5 9.0 8.6 8 0 0 8 8 8 8 Laminin EGF domain Laminin_N PF00055.17 RUS89304.1 - 7.2e-11 42.1 0.0 7.2e-11 42.1 0.0 3.5 4 1 0 4 4 4 1 Laminin N-terminal (Domain VI) HMMR_C PF15908.5 RUS89305.1 - 5e-17 62.6 13.8 5e-17 62.6 13.8 2.0 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal PMC2NT PF08066.12 RUS89305.1 - 0.065 13.9 2.0 2.8 8.7 0.1 2.5 2 0 0 2 2 2 0 PMC2NT (NUC016) domain SKA2 PF16740.5 RUS89305.1 - 0.11 12.3 15.7 0.051 13.4 4.0 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 T4SS PF07996.11 RUS89305.1 - 0.24 11.8 14.6 0.49 10.8 5.6 2.1 1 1 1 2 2 2 0 Type IV secretion system proteins TPR_MLP1_2 PF07926.12 RUS89305.1 - 0.56 10.3 30.0 0.86 9.7 12.0 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Dynactin_p22 PF07426.11 RUS89305.1 - 2.5 8.0 16.6 0.085 12.7 1.9 2.5 2 1 0 2 2 2 0 Dynactin subunit p22 Troponin PF00992.20 RUS89305.1 - 2.9 8.2 25.7 1.3e+02 2.9 23.3 3.0 1 1 1 2 2 2 0 Troponin DUF16 PF01519.16 RUS89305.1 - 9 6.8 18.9 6 7.4 9.0 2.7 1 1 0 2 2 2 0 Protein of unknown function DUF16 Ets PF00178.22 RUS89306.1 - 1.1e-36 125.1 0.2 1.7e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 Ets-domain Zn_clus PF00172.18 RUS89307.1 - 2.4 8.3 10.6 21 5.3 0.3 4.3 5 0 0 5 5 5 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 RUS89308.1 - 3 8.4 7.5 23 5.6 0.1 3.4 1 1 2 3 3 3 0 Zinc-finger of C2H2 type zf-CCCH PF00642.24 RUS89310.1 - 7.7e-14 51.2 16.6 7.9e-07 28.8 2.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 RUS89310.1 - 1.4e-07 31.3 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 RUS89310.1 - 2.1e-06 28.4 3.0 0.028 15.1 0.1 2.6 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 RUS89310.1 - 3.8e-05 23.6 14.4 0.015 15.3 2.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 RUS89310.1 - 0.019 15.1 3.3 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Nup35_RRM_2 PF14605.6 RUS89310.1 - 0.03 14.3 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BUD22 PF09073.10 RUS89311.1 - 0.035 13.5 14.1 0.042 13.2 14.1 1.1 1 0 0 1 1 1 0 BUD22 Sulfotransfer_1 PF00685.27 RUS89312.1 - 6.8e-46 156.9 0.4 5.6e-44 150.6 0.4 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS89312.1 - 4.1e-08 33.9 0.0 1e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family AAA_6 PF12774.7 RUS89313.1 - 2.1e-56 191.3 1.8 2.2e-47 161.6 0.3 4.5 4 1 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RUS89313.1 - 6e-43 146.5 0.0 1.3e-37 129.1 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 RUS89313.1 - 1.2e-18 67.4 0.1 3.7e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS89313.1 - 9.5e-15 54.8 0.0 1.5e-05 25.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RUS89313.1 - 2.7e-14 53.2 0.1 6.9e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_8 PF12780.7 RUS89313.1 - 8.2e-09 35.2 0.1 2.4e-07 30.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_16 PF13191.6 RUS89313.1 - 5.6e-08 33.4 0.0 0.015 15.7 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 RUS89313.1 - 1.9e-05 25.2 0.1 0.087 13.3 0.1 2.8 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 RUS89313.1 - 3.1e-05 24.3 0.0 0.14 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 RUS89313.1 - 4.4e-05 23.5 0.0 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 RUS89313.1 - 0.00011 22.6 0.1 0.12 12.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.6 RUS89313.1 - 0.00018 21.9 0.1 0.96 9.8 0.0 3.4 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 RUS89313.1 - 0.00034 20.0 0.0 0.11 11.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RUS89313.1 - 0.00057 20.3 0.0 0.62 10.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 RUS89313.1 - 0.0031 17.0 0.0 1.5 8.2 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein Viral_helicase1 PF01443.18 RUS89313.1 - 0.0033 17.2 0.1 0.51 10.0 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 RUS89313.1 - 0.004 17.1 0.3 0.097 12.6 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain NACHT PF05729.12 RUS89313.1 - 0.015 15.3 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 RUS89313.1 - 0.015 15.0 0.1 9.2 5.9 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 RUS89313.1 - 0.019 14.2 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 RUS89313.1 - 0.021 14.6 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 RUS89313.1 - 0.029 14.6 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 RUS89313.1 - 0.034 13.7 0.0 2.4 7.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 RUS89313.1 - 0.037 13.5 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 RUS89313.1 - 0.079 13.5 0.0 0.44 11.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 RUS89313.1 - 0.11 12.4 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 RUS89313.1 - 0.11 12.2 0.0 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 RUS89313.1 - 0.13 11.3 0.0 0.95 8.5 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain MT PF12777.7 RUS89314.1 - 2.3e-20 72.9 1.0 2.6e-20 72.8 0.0 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF4559 PF15112.6 RUS89314.1 - 0.00076 19.3 1.0 0.0015 18.3 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) AAA_9 PF12781.7 RUS89314.1 - 0.0046 16.1 0.7 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region FliT PF05400.13 RUS89314.1 - 0.1 13.5 5.5 0.29 12.0 5.5 1.8 1 0 0 1 1 1 0 Flagellar protein FliT Nup88 PF10168.9 RUS89314.1 - 0.67 7.7 5.5 1 7.0 5.5 1.2 1 0 0 1 1 1 0 Nuclear pore component Dynein_heavy PF03028.15 RUS89315.1 - 1.9e-11 44.1 0.0 6.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 RUS89315.1 - 6.2e-11 41.8 0.1 9.7e-11 41.2 0.1 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region DUF2201_N PF13203.6 RUS89315.1 - 1.3 8.5 4.2 1 8.9 1.5 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Dynein_C PF18199.1 RUS89316.1 - 3e-37 128.5 0.0 2e-32 112.7 0.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RUS89316.1 - 0.0045 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Ig_3 PF13927.6 RUS89317.1 - 1.6e-06 28.6 0.1 0.0072 16.9 0.0 3.9 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 RUS89317.1 - 3.3e-06 27.1 0.1 0.0014 18.6 0.0 3.8 4 2 0 4 4 4 1 Immunoglobulin I-set domain ig PF00047.25 RUS89317.1 - 1e-05 25.6 0.0 0.00029 21.0 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS89317.1 - 0.00079 19.7 0.0 0.0044 17.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.16 RUS89317.1 - 0.0021 16.9 0.0 0.044 12.5 0.0 2.2 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E V-set PF07686.17 RUS89317.1 - 0.0034 17.5 1.3 0.31 11.2 0.1 3.7 4 1 0 4 4 4 1 Immunoglobulin V-set domain Vpu PF00558.19 RUS89317.1 - 0.0062 16.3 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 Vpu protein Ig_6 PF18452.1 RUS89317.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Phage_Gp23 PF10669.9 RUS89317.1 - 4.6 7.6 5.8 1.7 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) 7TM_GPCR_Srw PF10324.9 RUS89318.1 - 2.1e-09 37.1 19.2 3.7e-09 36.3 19.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srt PF10321.9 RUS89318.1 - 4e-05 22.7 18.7 0.00022 20.3 15.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srt 7TM_GPCR_Srsx PF10320.9 RUS89318.1 - 0.016 14.6 21.5 0.083 12.3 21.5 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Flagellin_N PF00669.20 RUS89318.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Srg PF02118.21 RUS89318.1 - 0.22 11.2 33.6 0.01 15.5 18.1 3.3 2 2 1 3 3 3 0 Srg family chemoreceptor P22_Cro PF14549.6 RUS89319.1 - 0.15 11.9 0.0 14 5.6 0.0 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro NLRC4_HD2 PF17776.1 RUS89320.1 - 0.015 15.8 0.1 0.015 15.8 0.1 1.1 1 0 0 1 1 1 0 NLRC4 helical domain HD2 UPF0183 PF03676.14 RUS89321.1 - 2.5e-45 155.4 0.0 2.8e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.17 RUS89322.1 - 5.6e-72 240.8 2.5 5.6e-72 240.8 2.5 2.4 2 1 0 2 2 2 1 Core binding factor beta subunit SR-25 PF10500.9 RUS89322.1 - 1.3 8.6 14.6 2.4 7.7 14.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 RUS89324.1 - 9.4e-21 73.9 0.1 1.4e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2 PF00096.26 RUS89325.1 - 3e-14 52.6 58.4 6.2e-05 23.2 0.5 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89325.1 - 1.1e-12 47.7 51.3 0.0048 17.6 0.3 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS89325.1 - 8.8e-08 32.2 9.6 3e-06 27.4 2.1 7.1 7 1 0 7 7 7 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS89325.1 - 0.0014 18.5 1.9 0.0014 18.5 1.9 5.6 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS89325.1 - 0.096 12.5 0.1 0.096 12.5 0.1 4.4 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-met PF12874.7 RUS89325.1 - 0.33 11.4 0.0 0.33 11.4 0.0 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF4187 PF13821.6 RUS89325.1 - 0.46 10.3 0.1 0.46 10.3 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 RUS89325.1 - 0.71 10.2 26.8 0.75 10.2 1.7 5.0 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RUS89325.1 - 1 9.7 0.0 1 9.7 0.0 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding MRP-S27 PF10037.9 RUS89326.1 - 1.1e-67 228.6 0.5 1.4e-67 228.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 AF0941-like PF14591.6 RUS89326.1 - 1.2 9.7 12.9 1.5 9.4 6.2 2.6 1 1 1 2 2 2 0 AF0941-like YceD PF02620.17 RUS89326.1 - 3.2 7.9 6.4 29 4.8 3.1 2.5 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD DnaI_N PF07319.11 RUS89326.1 - 3.7 8.3 9.1 6.9 7.4 3.6 3.2 1 1 0 2 2 2 0 Primosomal protein DnaI N-terminus CLTH PF10607.9 RUS89327.1 - 1e-31 109.8 0.0 1.7e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 RUS89327.1 - 2.1e-05 24.4 0.2 4.6e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 RUS89327.1 - 0.001 18.5 0.1 0.003 17.0 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 RUS89327.1 - 0.0068 16.7 0.4 0.016 15.5 0.4 1.7 1 0 0 1 1 1 1 Ring finger domain Phage_Mu_Gam PF07352.12 RUS89327.1 - 0.1 12.5 0.5 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Flavi_glycoprot PF00869.20 RUS89328.1 - 0.017 14.3 0.0 0.021 14.1 0.0 1.0 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains I_LWEQ PF01608.17 RUS89330.1 - 2.3e-05 24.7 1.4 0.026 14.8 0.2 2.8 2 1 0 2 2 2 2 I/LWEQ domain Herpes_UL7 PF01677.16 RUS89330.1 - 0.016 14.9 0.1 0.064 13.0 0.1 1.9 1 1 1 2 2 2 0 Herpesvirus UL7 like Ion_trans PF00520.31 RUS89332.1 - 5.6e-103 343.4 32.1 2.7e-60 203.7 14.6 3.2 2 1 1 3 3 3 3 Ion transport protein GPHH PF16905.5 RUS89332.1 - 5.1e-30 103.0 0.2 9.6e-30 102.1 0.2 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 RUS89332.1 - 9.1e-29 99.5 0.1 1.8e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 RUS89332.1 - 3.4e-09 35.9 24.5 4.7e-09 35.4 4.1 4.2 3 1 1 4 4 4 3 Polycystin cation channel zf-C2H2 PF00096.26 RUS89333.1 - 1.2e-13 50.6 47.0 0.0014 19.0 0.8 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89333.1 - 4.1e-12 45.9 44.4 0.0031 18.2 2.9 7.9 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS89333.1 - 1.1e-10 41.4 41.7 0.00059 20.1 1.9 7.6 8 0 0 8 8 8 4 Zinc-finger double domain zf-met PF12874.7 RUS89333.1 - 0.00062 20.1 38.8 0.61 10.6 0.2 7.6 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS89333.1 - 0.00089 19.5 34.4 0.079 13.3 2.1 7.3 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RUS89333.1 - 0.013 15.3 0.1 0.013 15.3 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RUS89333.1 - 0.3 11.4 31.9 15 6.0 11.1 5.6 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RUS89333.1 - 2.9 8.4 22.5 6.3 7.3 0.3 4.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RUS89333.1 - 3.3 7.4 18.7 0.33 10.6 0.7 4.1 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 RUS89333.1 - 5.9 7.3 19.5 1.9 8.8 1.0 4.1 3 1 1 4 4 4 0 C2H2-type zinc ribbon Actin_micro PF17003.5 RUS89333.1 - 6.1 5.9 10.0 37 3.4 2.0 3.6 1 1 0 2 2 2 0 Putative actin-like family Ipi1_N PF12333.8 RUS89334.1 - 0.25 11.9 2.3 0.38 11.4 2.2 1.4 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Bin3 PF06859.12 RUS89335.1 - 4.2e-39 133.5 0.0 7.9e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 RUS89335.1 - 1.5e-11 44.3 0.0 2.6e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 RUS89335.1 - 4.4e-10 40.1 0.0 1.3e-06 29.0 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 RUS89335.1 - 1.1e-09 38.8 0.0 5.2e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS89335.1 - 1.7e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS89335.1 - 1.6e-07 32.0 0.0 8.8e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RUS89335.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RUS89335.1 - 0.00019 21.5 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RUS89335.1 - 0.0002 20.9 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RUS89335.1 - 0.00028 20.5 0.0 0.00076 19.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 RUS89335.1 - 0.0022 17.5 0.1 0.0088 15.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 RUS89335.1 - 0.0027 17.5 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RUS89335.1 - 0.016 14.6 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AP1AR PF15745.5 RUS89335.1 - 0.018 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein CMAS PF02353.20 RUS89335.1 - 0.064 12.5 0.0 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 RUS89335.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.19 RUS89335.1 - 0.13 12.4 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 RUS89335.1 - 0.2 10.5 0.0 0.85 8.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PWWP PF00855.17 RUS89336.1 - 1.1e-17 64.2 0.3 1.1e-17 64.2 0.3 4.8 4 1 1 5 5 5 1 PWWP domain zf-CW PF07496.15 RUS89336.1 - 1.4e-11 44.2 2.5 5.8e-11 42.2 2.5 2.2 1 0 0 1 1 1 1 CW-type Zinc Finger Glyco_hydro_31 PF01055.26 RUS89337.1 - 6.2e-51 174.0 0.0 9.6e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Raffinose_syn PF05691.12 RUS89337.1 - 0.13 10.0 0.0 0.18 9.6 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 2-Hacid_dh PF00389.30 RUS89338.1 - 8.9e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 RUS89338.1 - 2.3e-15 56.4 0.0 2.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OB_Dis3 PF17849.1 RUS89338.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Dis3-like cold-shock domain 2 (CSD2) DUF3331 PF11811.8 RUS89338.1 - 0.071 13.0 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3331) 2-Hacid_dh_C PF02826.19 RUS89340.1 - 4.1e-58 195.7 0.0 5.1e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RUS89340.1 - 3.4e-07 30.0 0.0 4.3e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RUS89340.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ferlin_C PF16165.5 RUS89341.1 - 8.8e-28 97.2 0.9 5.5e-25 88.1 0.1 2.4 1 1 1 2 2 2 2 Ferlin C-terminus C2 PF00168.30 RUS89341.1 - 6e-05 23.3 0.0 0.0013 19.0 0.1 2.5 2 1 0 2 2 2 1 C2 domain DUF3671 PF12420.8 RUS89341.1 - 0.07 13.2 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function B9-C2 PF07162.11 RUS89341.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein DHDPS PF00701.22 RUS89342.1 - 3.8e-52 176.8 0.0 4.4e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DiS_P_DiS PF06750.13 RUS89342.1 - 0.039 14.1 0.3 3.1 8.0 0.0 3.4 3 1 2 5 5 5 0 Bacterial Peptidase A24 N-terminal domain Homeodomain PF00046.29 RUS89344.1 - 6e-21 74.1 4.6 1.2e-20 73.1 4.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS89344.1 - 0.043 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain A_deaminase PF00962.22 RUS89345.1 - 3.6e-24 85.7 0.0 4.5e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rab_bind PF16704.5 RUS89345.1 - 0.062 13.3 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Rab binding domain Barwin PF00967.17 RUS89345.1 - 0.2 11.5 1.0 0.72 9.7 0.1 2.1 2 0 0 2 2 2 0 Barwin family DHR10 PF18595.1 RUS89346.1 - 0.0021 18.1 9.3 0.0021 18.1 9.3 2.2 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain MIP-T3_C PF17749.1 RUS89346.1 - 0.34 10.9 9.1 0.17 11.9 3.9 2.8 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region CLZ PF16526.5 RUS89346.1 - 1.3 9.4 15.9 0.75 10.2 4.0 3.7 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LPP PF04728.13 RUS89346.1 - 1.5 9.2 5.6 25 5.4 0.3 3.7 4 0 0 4 4 4 0 Lipoprotein leucine-zipper SH3_1 PF00018.28 RUS89347.1 - 7.1e-39 131.2 13.0 4.5e-10 39.0 0.4 4.4 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 RUS89347.1 - 1.2e-31 108.2 0.8 2e-08 33.8 0.1 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_9 PF14604.6 RUS89347.1 - 5.2e-31 106.3 10.3 3.6e-07 29.9 0.3 4.6 4 0 0 4 4 4 4 Variant SH3 domain PX PF00787.24 RUS89347.1 - 1.6e-19 69.9 0.0 3.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_3 PF08239.11 RUS89347.1 - 2.6e-13 50.0 12.8 0.034 14.4 0.3 4.5 4 0 0 4 4 4 4 Bacterial SH3 domain SH3_4 PF06347.13 RUS89347.1 - 8.2e-06 25.6 8.1 0.74 9.7 0.1 4.7 4 0 0 4 4 4 3 Bacterial SH3 domain SH3_16 PF18348.1 RUS89347.1 - 0.0075 16.0 7.4 2.1 8.2 0.1 4.3 4 0 0 4 4 4 1 Bacterial dipeptidyl-peptidase Sh3 domain DUF1604 PF07713.13 RUS89347.1 - 0.0097 15.7 3.5 0.056 13.3 0.2 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) CENP-B_dimeris PF09026.10 RUS89347.1 - 0.05 14.0 1.0 0.13 12.7 1.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DCR PF14047.6 RUS89347.1 - 0.086 13.1 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Dppa2/4 conserved region SH3_6 PF12913.7 RUS89347.1 - 0.27 10.8 0.1 0.27 10.8 0.1 3.7 4 1 0 4 4 4 0 SH3 domain (SH3b1 type) zf-B_box PF00643.24 RUS89348.1 - 1.5e-10 41.1 25.5 1.8e-09 37.6 10.2 4.7 5 0 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS89348.1 - 3.9e-09 36.4 6.2 3.9e-09 36.4 6.2 3.2 4 1 0 4 4 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS89348.1 - 6.3e-08 32.4 8.2 6.3e-08 32.4 8.2 4.0 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS89348.1 - 4.7e-07 29.6 8.2 4.7e-07 29.6 8.2 3.7 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS89348.1 - 7.4e-07 28.9 10.9 7.4e-07 28.9 10.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS89348.1 - 8.9e-07 29.0 8.9 8.9e-07 29.0 8.9 3.9 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RUS89348.1 - 5.4e-06 26.7 10.1 5.4e-06 26.7 10.1 3.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS89348.1 - 5.9e-06 26.0 9.1 5.9e-06 26.0 9.1 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS89348.1 - 0.00011 21.9 10.7 0.00011 21.9 10.7 3.9 4 1 1 5 5 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS89348.1 - 0.014 15.2 5.5 0.014 15.2 5.5 4.2 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain TFX_C PF14601.6 RUS89348.1 - 0.077 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term CMD PF02627.20 RUS89349.1 - 2.7e-13 49.8 0.7 5.8e-13 48.7 0.6 1.6 1 1 0 1 1 1 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 RUS89349.1 - 0.0004 19.4 0.0 0.00057 18.9 0.0 1.3 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) MMR_HSR1 PF01926.23 RUS89350.1 - 8.9e-24 83.8 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 RUS89350.1 - 1.6e-17 63.5 8.4 4.5e-17 62.1 8.5 1.7 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 RUS89350.1 - 4.8e-10 39.2 0.0 1.8e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 RUS89350.1 - 7e-06 25.2 0.3 0.012 14.6 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 RUS89350.1 - 0.016 14.8 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 RUS89350.1 - 0.018 14.6 0.0 6.5 6.3 0.0 2.5 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 RUS89350.1 - 0.032 14.3 0.1 2.3 8.3 0.1 2.5 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 RUS89350.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Amidohydro_2 PF04909.14 RUS89351.1 - 4.2e-69 233.5 0.6 4.8e-69 233.4 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M24 PF00557.24 RUS89352.1 - 5.7e-48 163.4 0.0 6.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.16 RUS89352.1 - 0.0067 17.0 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Med27 PF11571.8 RUS89353.1 - 1.2e-21 76.9 0.5 1.5e-21 76.5 0.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 27 GATase1_like PF07090.11 RUS89353.1 - 0.018 14.5 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase COX7C PF02935.16 RUS89354.1 - 7e-13 48.6 0.2 9.3e-13 48.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc TRM PF02005.16 RUS89355.1 - 3.1e-131 438.0 0.2 3.9e-131 437.7 0.2 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RUS89355.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RUS89355.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 RUS89355.1 - 0.015 14.5 0.1 0.026 13.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.13 RUS89355.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1279 PF06916.13 RUS89356.1 - 2e-19 69.9 0.4 3.3e-19 69.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) UPF0061 PF02696.14 RUS89357.1 - 1.4e-117 393.4 0.0 1.7e-117 393.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TPR_2 PF07719.17 RUS89358.1 - 2.3e-06 27.3 9.2 0.25 11.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS89358.1 - 4.3e-06 26.7 0.1 0.25 11.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS89358.1 - 8.7e-06 25.3 8.7 0.13 12.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS89358.1 - 0.0005 20.3 3.0 0.29 11.5 0.2 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RUS89358.1 - 0.00054 20.0 6.9 3.9 7.9 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RUS89358.1 - 0.0012 18.5 0.4 10 5.9 0.0 3.5 3 0 0 3 3 3 1 TPR repeat Sel1 PF08238.12 RUS89358.1 - 0.0043 17.7 1.9 16 6.3 0.0 3.9 3 0 0 3 3 3 1 Sel1 repeat TPR_19 PF14559.6 RUS89358.1 - 0.022 15.3 2.5 0.44 11.1 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat BCIP PF13862.6 RUS89358.1 - 0.033 14.0 0.2 0.033 14.0 0.2 1.7 2 0 0 2 2 2 0 p21-C-terminal region-binding protein ANAPC3 PF12895.7 RUS89358.1 - 0.34 11.2 8.5 0.16 12.2 0.6 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 RUS89359.1 - 8.7e-21 73.9 28.8 4.9e-05 24.0 1.8 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS89359.1 - 9.3e-09 35.5 0.1 1.3 9.3 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 RUS89359.1 - 0.0079 16.1 2.9 4.6 7.3 0.1 3.7 4 0 0 4 4 4 1 PQQ enzyme repeat PD40 PF07676.12 RUS89359.1 - 0.029 14.3 1.0 0.51 10.3 0.5 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 RUS89359.1 - 0.046 12.8 0.1 4.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region eIF2A PF08662.11 RUS89359.1 - 0.092 12.6 0.0 31 4.4 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF4930 PF16284.5 RUS89359.1 - 0.16 11.9 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) E1-E2_ATPase PF00122.20 RUS89360.1 - 1.7e-52 177.6 0.2 1.7e-52 177.6 0.2 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RUS89360.1 - 1.2e-45 155.4 3.9 1.2e-45 155.4 3.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RUS89360.1 - 2.9e-21 76.7 0.5 8.9e-21 75.1 0.5 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RUS89360.1 - 3.7e-18 65.0 0.3 1.1e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RUS89360.1 - 9.9e-16 57.6 0.0 2.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RUS89360.1 - 0.0049 16.6 1.1 0.011 15.5 1.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TRA-1_regulated PF02343.16 RUS89360.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 Pkinase PF00069.25 RUS89361.1 - 2e-67 227.4 0.1 2.3e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89361.1 - 1.6e-17 63.6 0.1 2.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS89361.1 - 1.6e-07 31.5 0.0 5.9e-06 26.4 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RUS89361.1 - 0.00022 20.6 0.1 0.00036 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS89361.1 - 0.0012 17.8 0.2 0.02 13.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 RUS89361.1 - 0.014 14.9 0.4 0.033 13.8 0.4 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 RUS89361.1 - 0.016 14.5 0.3 0.13 11.6 0.0 2.1 1 1 0 2 2 2 0 Kinase-like FTA2 PF13095.6 RUS89361.1 - 0.085 12.5 0.2 0.93 9.1 0.1 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Str_synth PF03088.16 RUS89362.1 - 2.1e-09 37.4 0.0 4.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 RUS89362.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region BACK PF07707.15 RUS89364.1 - 4.5e-12 46.0 4.7 7.9e-12 45.2 3.5 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch YopH_N PF09013.10 RUS89364.1 - 0.1 12.9 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 YopH, N-terminal SBF PF01758.16 RUS89365.1 - 1.1e-19 70.9 8.6 1.1e-19 70.9 8.6 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Pkinase PF00069.25 RUS89366.1 - 1.2e-67 228.0 0.0 1.9e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89366.1 - 5e-36 124.3 0.0 8.5e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS89366.1 - 3e-06 26.8 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RUS89366.1 - 0.077 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tyrosinase PF00264.20 RUS89368.1 - 4.1e-33 115.5 1.2 3e-30 106.2 1.2 2.4 1 1 0 1 1 1 1 Common central domain of tyrosinase CBM_14 PF01607.24 RUS89368.1 - 0.00017 21.7 6.1 0.00017 21.7 6.1 2.9 2 1 1 3 3 3 1 Chitin binding Peritrophin-A domain 7TM_GPCR_Srw PF10324.9 RUS89369.1 - 5.3e-10 39.1 11.6 1.4e-09 37.7 11.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS89369.1 - 6.1e-07 29.0 6.8 8.3e-07 28.6 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS89369.1 - 0.0015 18.0 12.7 0.0022 17.4 12.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DEAD PF00270.29 RUS89371.1 - 4.7e-19 68.8 0.1 1.4e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS89371.1 - 9.2e-17 61.4 0.7 3.1e-15 56.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS89371.1 - 2.9e-15 56.7 0.0 2.9e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C-RD PF11648.8 RUS89371.1 - 2.5e-13 50.3 0.5 5.8e-13 49.1 0.5 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 RUS89371.1 - 5.9e-06 26.3 1.0 5.9e-06 26.3 1.0 2.1 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain AAA_22 PF13401.6 RUS89371.1 - 0.00079 19.7 0.1 0.009 16.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 RUS89371.1 - 0.0056 16.2 2.0 0.25 10.8 0.1 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 RUS89371.1 - 0.035 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF520 PF04461.13 RUS89371.1 - 0.058 13.5 0.3 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF520) AAA_19 PF13245.6 RUS89371.1 - 0.089 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phospholip_A2_1 PF00068.19 RUS89372.1 - 1.4e-20 73.9 13.6 1.8e-20 73.4 13.6 1.2 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 RUS89372.1 - 0.0067 16.6 15.2 0.23 11.7 1.7 2.5 1 1 1 2 2 2 2 Phospholipase A2 Cas_Csy4 PF09618.10 RUS89372.1 - 0.09 12.9 1.3 0.17 12.0 1.0 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) 7tm_1 PF00001.21 RUS89373.1 - 2.6e-06 27.0 7.2 3.7e-06 26.5 7.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS89373.1 - 0.35 10.5 16.2 1.2 8.7 16.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Kelch_1 PF01344.25 RUS89374.1 - 6e-78 256.2 16.0 5.3e-16 57.9 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS89374.1 - 1.7e-39 132.8 6.5 3e-09 36.8 0.0 6.4 2 1 4 6 6 6 6 Kelch motif BACK PF07707.15 RUS89374.1 - 7.5e-29 99.9 0.3 5.7e-28 97.0 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 RUS89374.1 - 3e-26 90.4 6.0 1.9e-07 30.8 0.0 6.7 6 1 0 6 6 6 5 Kelch motif BTB PF00651.31 RUS89374.1 - 5.1e-26 91.1 0.1 1e-25 90.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 RUS89374.1 - 1.7e-25 88.8 4.8 4.5e-06 26.6 0.0 5.7 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS89374.1 - 3.7e-20 71.7 10.1 4.3e-05 23.7 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS89374.1 - 2e-09 37.2 10.1 0.61 10.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif L71 PF02448.15 RUS89374.1 - 0.19 12.2 1.3 35 4.9 0.1 3.3 3 0 0 3 3 3 0 L71 family Helicase_C PF00271.31 RUS89375.1 - 7.2e-18 64.9 0.0 1.1e-12 48.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 RUS89375.1 - 3.5e-14 53.0 0.0 8.4e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Drc1-Sld2 PF11719.8 RUS89375.1 - 8.8e-10 38.7 4.3 8.8e-10 38.7 4.3 2.5 1 1 0 2 2 2 1 DNA replication and checkpoint protein zf-CCHC PF00098.23 RUS89375.1 - 6.4e-05 22.9 4.8 0.00015 21.7 4.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS89375.1 - 0.0091 15.7 3.9 0.018 14.7 3.9 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 RUS89375.1 - 0.023 14.7 2.3 0.054 13.5 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle ResIII PF04851.15 RUS89375.1 - 0.033 14.2 0.0 0.17 11.9 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Phage_GPL PF05926.11 RUS89375.1 - 0.09 12.8 0.1 8.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Phage head completion protein (GPL) ABC_membrane PF00664.23 RUS89376.1 - 3.7e-05 23.5 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF615 PF04751.14 RUS89376.1 - 0.054 13.5 1.5 0.11 12.4 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF615) DUF4564 PF15169.6 RUS89376.1 - 0.059 13.1 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Flavi_M PF01004.19 RUS89376.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.0 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Na_Pi_cotrans PF02690.15 RUS89377.1 - 1.3e-39 135.5 23.1 1.2e-24 87.0 7.9 2.5 2 1 0 2 2 2 2 Na+/Pi-cotransporter AMP-binding_C PF13193.6 RUS89378.1 - 7.8e-09 36.4 0.0 1.1e-08 35.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 RUS89379.1 - 7.6e-16 57.7 0.0 8.7e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 RUS89380.1 - 3.3e-43 147.8 0.1 1.8e-23 82.9 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RUS89380.1 - 9.9e-06 26.4 0.0 6.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.32 RUS89381.1 - 4.1e-29 97.9 17.5 1.4e-08 33.6 1.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS89381.1 - 2.3e-26 92.0 13.5 1.8e-14 53.9 2.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS89381.1 - 2e-23 80.3 15.1 2.4e-07 30.1 0.2 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RUS89381.1 - 1.3e-18 66.5 15.8 7.8e-12 44.9 0.6 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RUS89381.1 - 1.4e-10 40.2 16.4 0.0002 20.7 1.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.6 RUS89381.1 - 2.4e-09 37.3 1.6 0.0005 20.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS89381.1 - 3.7e-05 23.6 7.1 0.0092 15.9 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RUS89381.1 - 0.0016 18.4 1.8 1.1 9.2 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 RUS89381.1 - 0.0072 16.6 4.1 0.15 12.3 1.1 2.2 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region HTH_40 PF14493.6 RUS89381.1 - 0.009 16.4 1.3 0.44 11.0 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain SUB1_ProdP9 PF18213.1 RUS89381.1 - 0.013 15.3 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 RUS89381.1 - 0.02 15.2 2.7 0.92 9.9 0.2 2.8 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 RUS89381.1 - 0.027 14.2 2.3 0.22 11.3 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain MgtE_N PF03448.17 RUS89381.1 - 0.68 10.6 6.2 0.16 12.5 0.5 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain 7tm_1 PF00001.21 RUS89382.1 - 6.1e-19 68.4 5.1 1.2e-18 67.4 5.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trypsin PF00089.26 RUS89382.1 - 0.11 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Trypsin DUF2701 PF10857.8 RUS89382.1 - 0.4 10.7 6.3 4.3 7.4 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) C1q PF00386.21 RUS89383.1 - 3.4e-22 79.0 0.1 4.7e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 C1q domain PA14 PF07691.12 RUS89383.1 - 0.0077 16.0 0.1 0.019 14.8 0.1 1.6 1 1 0 1 1 1 1 PA14 domain BclA_C PF18573.1 RUS89383.1 - 0.028 14.3 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 BclA C-terminal domain TIMELESS_C PF05029.13 RUS89383.1 - 0.059 12.5 1.4 0.074 12.2 1.4 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region NOB1_Zn_bind PF08772.11 RUS89384.1 - 3e-30 104.2 1.1 7e-30 103.0 1.1 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 RUS89384.1 - 5.2e-30 103.8 0.0 1.6e-29 102.2 0.0 1.9 1 0 0 1 1 1 1 PIN domain of ribonuclease Ribosomal_L37ae PF01780.19 RUS89384.1 - 0.038 14.1 1.3 0.27 11.3 0.2 2.6 2 1 1 3 3 3 0 Ribosomal L37ae protein family Ogr_Delta PF04606.12 RUS89384.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DZR PF12773.7 RUS89384.1 - 0.079 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 RUS89384.1 - 0.13 11.7 0.2 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 RUS89384.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 RUS89384.1 - 0.17 11.6 0.5 0.39 10.4 0.2 1.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RUS89384.1 - 0.24 11.4 1.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Myosin_head PF00063.21 RUS89385.1 - 6.3e-68 229.6 0.1 7.8e-68 229.3 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RUS89385.1 - 5.3e-46 156.7 0.2 8e-46 156.1 0.2 1.2 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Fz PF01392.22 RUS89386.1 - 3.7e-10 40.4 6.0 4.5e-10 40.1 6.0 1.1 1 0 0 1 1 1 1 Fz domain Glypican PF01153.19 RUS89386.1 - 0.032 13.1 2.3 0.036 12.9 2.3 1.1 1 0 0 1 1 1 0 Glypican Ldl_recept_a PF00057.18 RUS89387.1 - 7.4e-09 35.7 17.2 1.1e-08 35.1 9.3 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Fz PF01392.22 RUS89387.1 - 6.1e-08 33.3 8.0 1.1e-07 32.5 8.0 1.4 1 0 0 1 1 1 1 Fz domain Fz PF01392.22 RUS89388.1 - 6.8e-13 49.2 4.8 6.8e-13 49.2 4.8 2.0 1 1 1 2 2 2 1 Fz domain FSA_C PF10479.9 RUS89388.1 - 3.3 5.7 15.8 2.4 6.2 4.0 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus zf-C2H2 PF00096.26 RUS89391.1 - 3.8e-13 49.1 27.6 8.6e-06 25.9 1.2 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89391.1 - 2.4e-11 43.5 19.4 0.00081 20.0 0.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS89391.1 - 6.9e-11 42.1 7.2 4.4e-06 26.9 0.1 3.9 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS89391.1 - 7.6e-06 25.8 18.8 1.2e-05 25.1 0.4 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS89391.1 - 0.00052 20.2 11.7 0.24 11.7 3.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 RUS89391.1 - 0.0084 16.3 5.7 0.88 9.9 0.1 2.4 2 1 0 2 2 2 2 TFIIH C1-like domain zf-AN1 PF01428.16 RUS89391.1 - 0.019 15.1 13.7 0.61 10.3 2.8 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger GAGA PF09237.11 RUS89391.1 - 0.035 13.9 1.0 4.9 7.0 0.4 2.6 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 RUS89391.1 - 0.044 14.2 11.6 0.57 10.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RUS89391.1 - 0.082 13.0 7.5 0.1 12.7 1.9 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 RUS89391.1 - 0.1 12.5 13.5 1.7 8.6 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.22 RUS89391.1 - 0.2 11.9 6.9 6.9 7.0 0.1 2.5 2 1 0 2 2 2 0 LIM domain zf-CRD PF17979.1 RUS89391.1 - 0.5 10.5 7.5 0.97 9.5 2.2 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions XPA_N PF01286.18 RUS89391.1 - 0.76 9.9 6.7 21 5.3 0.3 3.2 3 0 0 3 3 3 0 XPA protein N-terminal Zf_RING PF16744.5 RUS89391.1 - 1.4 9.1 11.2 0.72 10.0 0.3 3.1 1 1 1 3 3 3 0 KIAA1045 RING finger FYVE PF01363.21 RUS89391.1 - 1.4 9.1 12.0 65 3.8 12.0 2.3 1 1 0 1 1 1 0 FYVE zinc finger DUF2180 PF09947.9 RUS89391.1 - 2.1 8.4 5.7 0.92 9.5 0.7 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-CHY PF05495.12 RUS89391.1 - 2.6 8.6 11.9 6.4 7.4 4.7 2.3 1 1 1 2 2 2 0 CHY zinc finger Elf1 PF05129.13 RUS89391.1 - 2.7 8.1 8.8 4 7.6 2.3 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like SelP_N PF04592.14 RUS89392.1 - 7.8 5.8 17.6 0.34 10.3 9.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Phage_r1t_holin PF16945.5 RUS89393.1 - 0.05 13.8 0.3 0.09 13.0 0.3 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin KCNQ_channel PF03520.14 RUS89394.1 - 5.3e-11 42.7 2.1 1.8e-10 41.0 2.1 1.8 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 RUS89395.1 - 1.1e-22 80.5 1.1 1.4e-22 80.1 1.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RUS89395.1 - 5.9e-13 48.6 5.8 5.9e-13 48.6 5.8 3.1 2 2 1 3 3 3 1 Ion channel UbiA PF01040.18 RUS89395.1 - 0.0048 16.2 0.6 0.0048 16.2 0.6 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family SecE PF00584.20 RUS89395.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.2 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex KAP PF05804.12 RUS89400.1 - 0.00082 17.7 0.3 0.001 17.4 0.3 1.2 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 RUS89400.1 - 0.033 14.6 0.0 0.25 11.8 0.0 2.4 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.23 RUS89402.1 - 0.0011 19.0 0.8 0.029 14.4 0.0 4.0 4 1 0 4 4 4 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 RUS89402.1 - 0.0053 16.7 1.7 0.095 12.7 0.3 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 RUS89402.1 - 0.028 14.4 0.4 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Arm_2 PF04826.13 RUS89402.1 - 0.043 13.3 3.3 0.38 10.2 0.2 2.5 1 1 1 2 2 2 0 Armadillo-like DUF4777 PF16007.5 RUS89402.1 - 0.091 13.0 0.0 1.9 8.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) KKLCAg1 PF15204.6 RUS89402.1 - 0.1 12.7 1.2 0.64 10.1 0.1 2.6 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 Atx10homo_assoc PF09759.9 RUS89402.1 - 0.29 11.2 1.9 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain PHD PF00628.29 RUS89403.1 - 1.7e-07 31.0 4.9 2.2e-07 30.7 3.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RUS89403.1 - 4.4e-05 22.9 2.6 0.00011 21.6 2.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 RUS89403.1 - 0.00029 20.7 1.7 0.00082 19.2 1.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RUS89403.1 - 0.024 15.0 3.5 0.091 13.1 1.4 2.4 2 0 0 2 2 2 0 C1 domain AT_hook PF02178.19 RUS89403.1 - 0.035 14.0 2.0 0.16 11.9 2.0 2.1 1 0 0 1 1 1 0 AT hook motif FYVE_2 PF02318.16 RUS89403.1 - 1.9 8.7 7.1 0.1 12.8 0.9 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger ERp29 PF07749.12 RUS89404.1 - 0.0013 19.6 0.4 0.0018 19.2 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain DUF4298 PF14131.6 RUS89404.1 - 0.38 10.7 2.9 0.64 10.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Thioredoxin PF00085.20 RUS89405.1 - 0.0003 20.7 0.0 0.00035 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 RUS89405.1 - 0.011 15.6 0.0 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain HyaE PF07449.11 RUS89405.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.1 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE CBM_21 PF03370.13 RUS89406.1 - 1.1e-25 90.0 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RUS89406.1 - 2.8e-10 40.6 0.3 6.8e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DLIC PF05783.11 RUS89407.1 - 3.2e-128 428.5 0.0 3.7e-128 428.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 RUS89407.1 - 0.0013 19.3 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 RUS89407.1 - 0.0027 17.9 0.0 0.0071 16.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RUS89407.1 - 0.005 16.3 0.0 0.85 9.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein GTP_EFTU PF00009.27 RUS89407.1 - 0.0059 16.2 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS89407.1 - 0.008 16.1 0.1 6.3 6.7 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase G-alpha PF00503.20 RUS89407.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Ras PF00071.22 RUS89407.1 - 0.018 14.6 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 RUS89407.1 - 0.019 14.5 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 RUS89407.1 - 0.041 13.6 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NOC3p PF07540.11 RUS89407.1 - 0.049 14.1 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Nucleolar complex-associated protein DLIC PF05783.11 RUS89408.1 - 3.6e-08 32.7 5.1 9.8e-08 31.3 5.1 1.6 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) DEC-1_N PF04625.13 RUS89408.1 - 0.27 10.2 5.7 0.34 9.9 5.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GMC_oxred_N PF00732.19 RUS89409.1 - 1.2e-81 274.4 0.0 1.6e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RUS89409.1 - 3e-39 134.8 0.0 6.7e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 RUS89409.1 - 1.2e-06 27.9 0.1 0.037 13.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 RUS89409.1 - 0.00015 21.9 0.6 0.00043 20.5 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RUS89409.1 - 0.00031 19.9 0.1 0.00054 19.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 RUS89409.1 - 0.00097 18.8 3.0 0.0076 15.9 3.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RUS89409.1 - 0.049 12.3 0.1 0.17 10.5 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 RUS89409.1 - 0.05 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS89409.1 - 0.11 11.5 0.2 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 RUS89409.1 - 0.12 11.6 0.1 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family UQ_con PF00179.26 RUS89410.1 - 4.4e-46 156.0 0.0 5.3e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RUS89410.1 - 0.09 13.1 0.1 0.19 12.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 RUS89410.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 UEV domain DUF1640 PF07798.11 RUS89411.1 - 1.9e-47 161.6 5.7 3e-47 160.9 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DHC_N2 PF08393.13 RUS89411.1 - 0.00042 19.5 1.3 0.00054 19.2 1.3 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Utp12 PF04003.12 RUS89411.1 - 0.032 14.6 0.6 2.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family Mss4 PF04421.13 RUS89411.1 - 0.16 12.1 1.4 0.38 10.9 0.1 2.2 2 1 0 3 3 3 0 Mss4 protein POX PF07526.11 RUS89411.1 - 0.62 10.6 4.7 0.27 11.8 1.4 1.9 2 0 0 2 2 2 0 Associated with HOX GST_N_3 PF13417.6 RUS89413.1 - 4.3e-09 36.7 0.0 7.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS89413.1 - 1.9e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS89413.1 - 2e-06 28.0 0.0 3.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RUS89413.1 - 2.1e-05 24.4 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS89413.1 - 2.1e-05 24.6 0.0 4.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS89413.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2515 PF10720.9 RUS89413.1 - 0.038 13.2 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) HOIP-UBA PF16678.5 RUS89414.1 - 7.3e-32 110.5 3.9 3.6e-31 108.2 3.0 2.5 2 0 0 2 2 2 1 HOIP UBA domain pair E3_UbLigase_RBR PF18091.1 RUS89414.1 - 7.8e-28 96.4 0.1 2.5e-27 94.8 0.1 2.0 1 0 0 1 1 1 1 E3 Ubiquitin Ligase RBR C-terminal domain IBR PF01485.21 RUS89414.1 - 4e-11 43.0 24.4 4.2e-08 33.3 5.6 5.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain PUB PF09409.10 RUS89414.1 - 3e-08 33.5 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 PUB domain Peptidase_C39 PF03412.15 RUS89414.1 - 0.07 12.9 0.1 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Peptidase C39 family Ank PF00023.30 RUS89415.1 - 5.8e-07 29.7 0.1 1.6e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 RUS89415.1 - 8.5e-06 26.3 0.1 4.5e-05 23.9 0.1 1.8 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS89415.1 - 2.9e-05 24.3 0.0 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89415.1 - 2.9e-05 24.1 0.1 6.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 RUS89415.1 - 0.00011 22.6 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FA PF08736.11 RUS89415.1 - 0.078 13.1 4.6 0.43 10.7 0.1 3.3 3 0 0 3 3 3 0 FERM adjacent (FA) ubiquitin PF00240.23 RUS89416.1 - 2.7e-08 33.4 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RUS89416.1 - 0.0003 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zf_RING PF16744.5 RUS89417.1 - 1e-21 76.8 7.7 1.9e-21 76.0 5.7 2.5 3 0 0 3 3 3 1 KIAA1045 RING finger EF-hand_6 PF13405.6 RUS89417.1 - 1.9e-10 39.8 4.8 0.022 14.7 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 RUS89417.1 - 2.8e-10 39.9 4.4 0.0029 17.4 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.6 RUS89417.1 - 4.9e-10 39.7 26.7 4.6e-05 23.8 5.6 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 RUS89417.1 - 3.6e-09 35.5 4.7 0.0028 17.1 0.2 4.3 4 0 0 4 4 4 3 EF hand C1_1 PF00130.22 RUS89417.1 - 0.0066 16.3 3.9 0.0066 16.3 3.9 2.7 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 RUS89417.1 - 0.03 14.2 3.4 0.077 12.9 3.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 RUS89417.1 - 0.1 12.5 8.4 0.4 10.6 8.4 2.1 1 1 0 1 1 1 0 PHD-finger EF-hand_5 PF13202.6 RUS89417.1 - 0.14 11.7 9.1 0.17 11.4 0.1 3.6 3 0 0 3 3 3 0 EF hand Amidase PF01425.21 RUS89418.1 - 4.7e-120 401.6 6.9 2.4e-59 201.5 0.0 3.7 1 1 3 4 4 4 3 Amidase Amidase PF01425.21 RUS89419.1 - 1.2e-83 281.6 0.0 1.7e-83 281.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 RUS89420.1 - 8.4e-16 58.0 0.0 9.6e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Amidase NTP_transferase PF00483.23 RUS89421.1 - 9.9e-16 58.1 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RUS89421.1 - 1.8e-14 54.4 0.0 2.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RUS89421.1 - 4.7e-10 38.8 10.7 0.001 18.7 0.0 4.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 RUS89421.1 - 9.5e-06 24.8 9.6 9.5e-06 24.8 9.6 2.1 2 1 0 2 2 2 1 L-fucokinase DUF4954 PF16314.5 RUS89421.1 - 1.3e-05 23.6 7.5 8.4e-05 20.9 7.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 RUS89421.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 RUS89421.1 - 0.073 12.8 12.5 0.76 9.6 1.1 3.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Aldo_ket_red PF00248.21 RUS89422.1 - 2.2e-68 230.6 0.0 2.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L7Ae PF01248.26 RUS89424.1 - 6.1e-07 29.1 0.1 9.8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CxC6 PF18721.1 RUS89424.1 - 1.9 8.8 5.8 6.2 7.2 0.1 3.1 3 0 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases ASC PF00858.24 RUS89425.1 - 3.6e-13 49.3 11.3 4.1e-13 49.1 11.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Gsf2 PF11055.8 RUS89425.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Glucose signalling factor 2 ASC PF00858.24 RUS89426.1 - 2.9e-16 59.5 0.1 3.2e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SmpB PF01668.18 RUS89426.1 - 0.056 13.3 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 SmpB protein ASC PF00858.24 RUS89427.1 - 2e-64 218.2 0.1 2.5e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Nefa_Nip30_N PF10187.9 RUS89427.1 - 0.11 12.9 1.9 0.23 11.9 0.9 2.0 2 1 1 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 AMP-binding PF00501.28 RUS89428.1 - 4.5e-32 111.2 0.0 2.4e-31 108.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS89428.1 - 0.029 15.3 0.0 0.069 14.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Vasculin PF15337.6 RUS89429.1 - 1.5e-08 35.4 0.7 1.5e-08 35.4 0.7 2.9 3 0 0 3 3 3 1 Vascular protein family Vasculin-like 1 Ndc1_Nup PF09531.10 RUS89430.1 - 3.6e-17 62.3 0.0 3.9e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup LRR_8 PF13855.6 RUS89431.1 - 1.8e-15 56.5 26.4 5.1e-06 26.1 10.8 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RUS89431.1 - 4.4e-12 46.0 28.3 2e-06 28.0 3.3 5.1 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS89431.1 - 0.011 15.2 11.0 0.28 10.7 1.2 2.7 1 1 0 2 2 2 0 Leucine-rich repeat DUF4407 PF14362.6 RUS89431.1 - 0.27 10.6 1.3 0.38 10.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mucin PF01456.17 RUS89431.1 - 7.5 6.5 9.1 11 5.9 9.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_18 PF00704.28 RUS89432.1 - 3.8e-16 59.7 0.0 4.7e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M3 PF01432.20 RUS89433.1 - 2.3e-112 376.6 0.1 3.2e-112 376.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 PLAC8 PF04749.17 RUS89434.1 - 1e-06 29.6 5.0 1.8e-06 28.9 5.0 1.6 1 1 0 1 1 1 1 PLAC8 family Antistasin PF02822.14 RUS89435.1 - 5e-09 36.6 24.8 7e-08 33.0 10.5 5.5 5 2 0 5 5 5 3 Antistasin family 7tm_1 PF00001.21 RUS89436.1 - 2.2e-56 191.1 13.2 3e-56 190.7 13.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS89436.1 - 7.9e-18 64.8 12.5 1.3e-17 64.1 12.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 RUS89436.1 - 0.028 14.2 9.6 0.056 13.2 9.6 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF2116 PF09889.9 RUS89436.1 - 5.1 7.2 6.4 7.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CDC27 PF09507.10 RUS89437.1 - 0.11 11.9 63.1 0.14 11.5 63.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 RUS89437.1 - 1 9.3 35.0 1.3 9.0 35.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 RUS89437.1 - 1.2 7.8 22.6 1.6 7.5 22.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Neuregulin PF02158.15 RUS89437.1 - 3.9 6.7 23.9 5.5 6.3 23.9 1.3 1 0 0 1 1 1 0 Neuregulin intracellular region ArAE_2_N PF10337.9 RUS89438.1 - 0.76 8.7 5.1 0.84 8.6 5.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Phage_holin_3_6 PF07332.11 RUS89438.1 - 8.9 6.4 10.4 13 5.8 10.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III dNK PF01712.19 RUS89439.1 - 2.2e-48 164.8 0.0 3.3e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 RUS89439.1 - 3.1e-05 24.2 0.0 0.0019 18.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RUS89439.1 - 3.2e-05 24.5 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 RUS89439.1 - 0.031 13.4 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 RUS89439.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 RUS89439.1 - 0.081 13.3 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS89439.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 RUS89439.1 - 0.12 12.7 0.1 0.6 10.5 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 RUS89439.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF4131 PF13567.6 RUS89441.1 - 0.15 11.7 0.3 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 RUS89441.1 - 0.81 9.7 2.5 1.3 9.1 2.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 RUS89441.1 - 1.6 7.4 4.0 2.3 6.9 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 RUS89441.1 - 4.8 6.2 4.8 6.8 5.7 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein BIR PF00653.21 RUS89443.1 - 1.9e-26 92.5 1.4 3.8e-26 91.5 1.4 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 RUS89443.1 - 0.0088 16.1 1.5 0.2 11.7 1.1 2.4 1 1 1 2 2 2 1 C3HC zinc finger-like zf-BED PF02892.15 RUS89443.1 - 0.09 12.8 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 BED zinc finger SPX PF03105.19 RUS89445.1 - 0.015 15.3 3.8 0.016 15.1 3.8 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 RUS89445.1 - 0.25 10.1 0.4 0.29 9.8 0.4 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 RUS89445.1 - 0.58 8.9 7.1 0.74 8.6 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 RUS89445.1 - 3.2 7.0 10.4 4.5 6.5 10.4 1.2 1 0 0 1 1 1 0 FAM76 protein Tom22 PF04281.13 RUS89446.1 - 7.6e-13 48.4 0.1 9e-13 48.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Claudin_2 PF13903.6 RUS89447.1 - 5e-07 29.7 1.2 0.012 15.4 0.2 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 RUS89447.1 - 0.00083 19.3 0.3 0.037 14.0 0.0 2.1 2 0 0 2 2 2 1 Tight junction protein, Claudin-like Abhydrolase_9_N PF15420.6 RUS89447.1 - 0.0028 17.7 1.4 0.012 15.6 0.1 1.9 1 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus PMP22_Claudin PF00822.20 RUS89447.1 - 0.0077 16.1 1.3 0.079 12.8 0.1 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF3040 PF11239.8 RUS89447.1 - 0.019 15.3 2.4 4 7.8 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4293 PF14126.6 RUS89447.1 - 0.033 14.4 1.7 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) SUR7 PF06687.12 RUS89447.1 - 0.1 12.2 1.3 0.21 11.2 1.3 1.5 1 1 0 1 1 1 0 SUR7/PalI family Neurensin PF14927.6 RUS89447.1 - 0.24 11.1 3.4 0.69 9.6 0.0 2.3 2 1 0 2 2 2 0 Neurensin DUF3185 PF11381.8 RUS89447.1 - 0.58 10.2 4.9 4.5 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) adh_short_C2 PF13561.6 RUS89448.1 - 2e-16 60.2 0.0 2.3e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Swi5 PF07061.11 RUS89451.1 - 2.4e-23 82.0 2.2 3.4e-23 81.5 2.2 1.2 1 0 0 1 1 1 1 Swi5 Cauli_AT PF03233.13 RUS89451.1 - 0.0078 16.2 0.1 0.0099 15.8 0.1 1.1 1 0 0 1 1 1 1 Aphid transmission protein Phage_GP20 PF06810.11 RUS89451.1 - 0.08 12.7 1.1 0.11 12.3 1.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 PKcGMP_CC PF16808.5 RUS89451.1 - 0.17 11.7 1.7 1.1 9.2 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Rieske_2 PF13806.6 RUS89452.1 - 1.5e-09 37.7 0.0 1.7e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 RUS89452.1 - 2.6e-09 36.9 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SCP2 PF02036.17 RUS89453.1 - 3.6e-27 94.8 2.1 7.4e-27 93.8 2.1 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 RUS89453.1 - 3e-22 79.2 0.0 4.7e-20 72.0 0.0 2.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS89453.1 - 6.2e-13 48.5 0.1 4.4e-12 45.7 0.1 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RUS89453.1 - 3e-06 27.0 2.3 0.0041 16.7 0.5 3.2 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Alkyl_sulf_C PF14864.6 RUS89453.1 - 3.3e-05 24.2 1.1 5.5e-05 23.5 0.4 1.6 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal ACP_syn_III PF08545.10 RUS89453.1 - 6.6e-05 22.7 0.1 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 RUS89453.1 - 0.00055 18.7 0.2 0.0018 17.0 0.1 1.8 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 RUS89453.1 - 0.0073 16.3 0.4 0.078 13.0 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain MAP PF03642.13 RUS89453.1 - 0.035 14.4 0.4 0.1 12.9 0.4 1.7 1 0 0 1 1 1 0 MAP domain SCP2_2 PF13530.6 RUS89453.1 - 0.042 14.2 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 Sterol carrier protein domain SCP2 PF02036.17 RUS89454.1 - 2.3e-26 92.2 1.4 3.4e-26 91.7 1.4 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RUS89454.1 - 2.4e-06 27.9 0.1 3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 RUS89454.1 - 0.024 15.0 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain WPP PF13943.6 RUS89454.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 2 0 0 2 2 2 0 WPP domain DUF2181 PF10223.9 RUS89455.1 - 2.3e-65 220.4 0.2 3e-65 220.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Importin_rep_3 PF18806.1 RUS89456.1 - 4.9e-27 93.8 0.0 1.4e-26 92.3 0.0 1.9 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep PF18773.1 RUS89456.1 - 2.6e-22 78.2 1.8 2.6e-22 78.2 1.8 2.0 3 0 0 3 3 3 1 Importin 13 repeat Xpo1 PF08389.12 RUS89456.1 - 1.3e-19 70.8 9.6 3.5e-19 69.3 0.9 4.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 RUS89456.1 - 8.3e-07 28.8 0.0 4.4e-06 26.5 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_2 PF18786.1 RUS89456.1 - 0.0002 21.1 0.4 0.00065 19.5 0.4 1.9 1 0 0 1 1 1 1 Importin 13 repeat DUF3342 PF11822.8 RUS89456.1 - 0.029 14.6 0.3 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) PDZ PF00595.24 RUS89458.1 - 1.8e-117 383.9 28.1 1.1e-18 67.4 0.0 7.2 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 RUS89458.1 - 3.4e-63 209.3 15.0 5.7e-11 42.1 0.0 7.4 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 RUS89458.1 - 1.6e-37 127.7 17.3 9e-05 22.7 0.1 7.5 7 0 0 7 7 7 7 PDZ domain PDZ_4 PF17816.1 RUS89458.1 - 1.3e-06 28.7 1.8 14 6.1 0.0 6.9 7 0 0 7 7 7 1 PDZ domain Maf_N PF08383.11 RUS89458.1 - 0.19 11.6 0.0 4.7 7.1 0.0 2.7 3 0 0 3 3 3 0 Maf N-terminal region MSP1_C PF07462.11 RUS89458.1 - 2.9 6.5 3.4 5 5.7 3.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PDZ PF00595.24 RUS89459.1 - 3.4e-11 43.3 0.0 7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS89459.1 - 4.3e-06 26.5 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS89459.1 - 0.016 15.6 0.0 0.057 13.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Integrase_Zn PF02022.19 RUS89459.1 - 0.19 11.7 0.4 0.37 10.8 0.4 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Dynein_C PF18199.1 RUS89460.1 - 4.1e-44 151.0 0.6 3.2e-43 148.1 0.1 2.6 2 1 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RUS89460.1 - 4.6e-29 101.1 4.4 4.2e-15 55.5 0.0 4.8 4 1 0 4 4 4 3 ATP-binding dynein motor region Dynein_heavy PF03028.15 RUS89460.1 - 2.1e-14 53.7 0.0 3.1e-13 49.9 0.0 2.9 2 1 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RUS89460.1 - 2.9e-11 43.0 0.1 4.2e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF745 PF05335.13 RUS89460.1 - 3.1 7.5 11.5 4.1 7.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Snurportin1 PF11538.8 RUS89461.1 - 2.9e-15 56.1 5.5 2.9e-15 56.1 5.5 1.9 2 0 0 2 2 2 1 Snurportin1 IBB PF01749.20 RUS89461.1 - 0.0072 16.7 2.5 0.0072 16.7 2.5 2.3 2 0 0 2 2 2 1 Importin beta binding domain mRNA_cap_enzyme PF01331.19 RUS89461.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Jiraiya PF15038.6 RUS89462.1 - 2.1e-25 89.1 7.1 8.6e-25 87.1 1.6 2.1 2 0 0 2 2 2 2 Jiraiya GT87 PF09594.10 RUS89462.1 - 0.0017 18.1 0.4 0.0074 16.0 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase family 87 GlpM PF06942.12 RUS89462.1 - 0.012 16.0 0.1 0.012 16.0 0.1 2.0 3 0 0 3 3 3 0 GlpM protein DUF3147 PF11345.8 RUS89462.1 - 0.059 13.7 0.3 0.059 13.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Yip1 PF04893.17 RUS89462.1 - 3.9 7.2 10.2 19 4.9 10.2 2.0 1 1 0 1 1 1 0 Yip1 domain DUF202 PF02656.15 RUS89462.1 - 5.7 7.5 8.6 1.1 9.8 0.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) RRM_1 PF00076.22 RUS89463.1 - 0.0031 17.3 0.0 0.0087 15.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2838 PF10998.8 RUS89464.1 - 4.7e-31 107.3 14.9 4.7e-31 107.3 14.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) GAF PF01590.26 RUS89465.1 - 2e-17 64.1 0.1 3.2e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 RUS89465.1 - 1.1e-13 51.6 0.0 3.6e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 RUS89465.1 - 7.9e-08 32.7 0.0 0.0036 17.7 0.0 2.3 2 0 0 2 2 2 2 GAF domain FANCI_S4 PF14678.6 RUS89465.1 - 0.023 13.9 1.3 0.029 13.5 1.3 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 MatP PF06303.12 RUS89466.1 - 7.5 7.2 23.1 24 5.6 1.8 5.4 1 1 5 6 6 6 0 MatP N-terminal domain Circo_capsid PF02443.15 RUS89468.1 - 0.00034 20.3 15.9 0.00051 19.7 15.9 1.3 1 0 0 1 1 1 1 Circovirus capsid protein Nop53 PF07767.11 RUS89468.1 - 1.4 8.2 65.7 2.4 7.4 65.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 RUS89468.1 - 4.9 7.1 73.0 1.6 8.7 57.5 2.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) TFIIA PF03153.13 RUS89469.1 - 0.0085 16.1 40.6 0.015 15.3 40.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 RUS89469.1 - 0.12 10.4 22.9 0.15 10.1 22.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 RUS89469.1 - 0.59 8.9 27.1 0.65 8.8 27.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PDEase_I PF00233.19 RUS89470.1 - 1.8e-77 260.2 8.6 2.2e-77 260.0 8.6 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ParD_like PF11903.8 RUS89470.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system FRG1 PF06229.12 RUS89471.1 - 2.3e-72 242.7 0.2 2.3e-72 242.7 0.2 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 RUS89471.1 - 3.2e-11 43.4 0.1 1.2e-10 41.6 0.0 1.9 2 1 1 3 3 3 1 Fascin domain DUF1754 PF08555.10 RUS89471.1 - 9.8e-06 26.3 1.9 9.8e-06 26.3 1.9 2.2 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) BTB PF00651.31 RUS89472.1 - 2.4e-18 66.4 0.1 1.6e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS89472.1 - 9.4e-17 61.0 1.4 5.2e-14 52.2 0.6 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch ANAPC_CDC26 PF10471.9 RUS89472.1 - 6 7.8 8.9 0.61 11.0 2.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Sedlin_N PF04628.13 RUS89473.1 - 8.5e-50 168.3 1.4 9.5e-50 168.1 1.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RUS89473.1 - 2.4e-09 37.2 0.2 3.8e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Sybindin-like family DUF2012 PF09430.10 RUS89474.1 - 1.5e-28 99.4 0.0 2.2e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF2812 PF11193.8 RUS89475.1 - 0.039 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) GFA PF04828.14 RUS89475.1 - 0.091 13.1 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Frag1 PF10277.9 RUS89476.1 - 8.6e-39 133.3 10.6 1.1e-38 133.0 10.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TMEM138 PF14935.6 RUS89476.1 - 0.091 13.4 1.2 0.18 12.5 1.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 138 Frag1 PF10277.9 RUS89477.1 - 2.7e-37 128.4 16.3 3.2e-37 128.2 16.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Herpes_gE PF02480.16 RUS89478.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.12 RUS89478.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ANAPC15 PF15243.6 RUS89479.1 - 5.2e-28 97.3 15.7 7.1e-28 96.9 15.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Na_trans_assoc PF06512.13 RUS89479.1 - 0.034 14.4 10.3 0.038 14.3 10.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated VIR_N PF15912.5 RUS89479.1 - 1.1 8.8 9.2 1.1 8.8 9.2 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 RUS89479.1 - 4.5 5.4 18.2 5.1 5.3 18.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 RUS89479.1 - 6.1 5.9 21.2 6.9 5.7 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 RUS89479.1 - 8.6 4.4 17.0 9.3 4.3 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 RUS89479.1 - 8.7 5.4 15.4 8.8 5.4 15.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3100 PF11299.8 RUS89480.1 - 0.036 13.5 0.2 0.058 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) DUF2533 PF10752.9 RUS89481.1 - 0.007 16.8 3.4 12 6.5 0.3 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF2533) DUF630 PF04783.12 RUS89481.1 - 0.01 16.0 0.2 1.3e+02 2.9 0.1 4.2 1 1 5 6 6 6 0 Protein of unknown function (DUF630) D_CNTX PF17492.2 RUS89481.1 - 0.019 15.1 11.4 9.2 6.5 0.2 4.4 1 1 4 5 5 5 0 Delta Ctenitoxins FSAP_sig_propep PF03032.15 RUS89481.1 - 0.14 12.2 10.8 77 3.4 0.1 5.6 2 1 4 6 6 6 0 Frog skin active peptide family signal and propeptide BLF1 PF17752.1 RUS89481.1 - 0.26 10.6 1.3 18 4.5 0.1 2.3 1 1 2 3 3 3 0 Burkholderia lethal factor 1 Ipi1_N PF12333.8 RUS89482.1 - 0.13 12.9 0.1 0.32 11.6 0.1 1.6 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Sarcoglycan_1 PF04790.13 RUS89483.1 - 6.3e-05 22.5 3.9 7.1e-05 22.3 2.7 1.6 2 0 0 2 2 2 1 Sarcoglycan complex subunit protein MADF_DNA_bdg PF10545.9 RUS89484.1 - 3.8e-18 65.6 0.3 5.8e-18 65.0 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like ubiquitin PF00240.23 RUS89485.1 - 0 996.9 46.3 1.6e-33 114.3 0.3 9.0 9 0 0 9 9 9 9 Ubiquitin family Rad60-SLD PF11976.8 RUS89485.1 - 1.5e-146 476.5 48.2 1.7e-15 56.6 0.4 9.0 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RUS89485.1 - 1.1e-54 182.8 22.3 0.00038 20.9 0.1 11.3 9 9 0 9 9 9 9 Ubiquitin-like domain TBK1_ULD PF18396.1 RUS89485.1 - 1.2e-33 114.8 16.3 0.075 13.0 0.0 9.2 9 0 0 9 9 9 9 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 RUS89485.1 - 9.7e-30 102.8 21.3 0.16 12.3 0.1 9.1 9 0 0 9 9 9 9 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RUS89485.1 - 1.3e-29 102.6 15.9 0.25 11.4 0.0 10.2 9 0 0 9 9 9 9 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RUS89485.1 - 1.1e-25 90.1 5.3 1.7 9.2 0.0 9.2 1 1 3 9 9 9 9 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 RUS89485.1 - 1.3e-12 47.9 0.0 80 3.7 0.0 9.6 9 0 0 9 9 9 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 RUS89485.1 - 4.7e-11 42.8 15.2 17 5.6 0.0 8.6 9 0 0 9 9 9 0 UDP-glucose:Glycoprotein Glucosyltransferase RBD PF02196.15 RUS89485.1 - 6.4e-11 42.2 0.0 1e+02 3.1 0.0 9.1 9 0 0 9 9 9 0 Raf-like Ras-binding domain DUF969 PF06149.12 RUS89485.1 - 3.6e-09 36.4 0.6 69 2.8 0.0 8.4 9 0 0 9 9 9 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 RUS89485.1 - 7.6e-08 32.3 58.4 69 3.6 0.0 17.5 18 0 0 18 18 18 0 Ubiquitin-like domain Big_7 PF17957.1 RUS89485.1 - 1.6e-07 32.0 0.0 4.1e+02 1.8 0.0 8.5 9 0 0 9 9 9 0 Bacterial Ig domain ORF11CD3 PF10549.9 RUS89485.1 - 2.5e-07 30.7 0.0 2.5e+02 1.9 0.0 8.8 9 0 0 9 9 9 0 ORF11CD3 domain DUF3861 PF12977.7 RUS89485.1 - 1.4e-06 28.3 11.4 1.3e+02 2.8 0.0 8.9 9 0 0 9 9 9 0 Domain of Unknown Function with PDB structure (DUF3861) TraK PF06586.11 RUS89485.1 - 0.00018 21.3 4.9 2.6e+02 1.1 0.0 8.0 9 0 0 9 9 9 0 TraK protein CorA PF01544.18 RUS89485.1 - 0.026 13.8 10.4 2.3e+02 0.9 0.0 7.8 9 0 0 9 9 9 0 CorA-like Mg2+ transporter protein FlgD_ig PF13860.6 RUS89485.1 - 0.034 14.0 22.3 1.6e+02 2.3 0.1 8.9 9 0 0 9 9 9 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 RUS89485.1 - 0.052 14.0 16.7 1.8e+02 2.7 0.4 8.1 1 1 1 2 2 1 0 Phage tail sheath protein beta-sandwich domain ProRS-C_2 PF09181.10 RUS89485.1 - 0.14 12.3 16.5 3.4e+02 1.5 0.0 8.3 9 0 0 9 9 9 0 Prolyl-tRNA synthetase, C-terminal Pro_isomerase PF00160.21 RUS89486.1 - 1e-37 129.9 0.2 5e-37 127.6 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LAMTOR PF15454.6 RUS89486.1 - 2e-13 50.7 4.3 3.2e-13 50.1 4.3 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ASC PF00858.24 RUS89487.1 - 7.4e-73 246.0 11.6 2.6e-71 240.9 11.6 2.1 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel IQ PF00612.27 RUS89488.1 - 2e-05 23.9 2.3 3.4e-05 23.2 2.3 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif PPP5 PF08321.12 RUS89489.1 - 0.0067 16.7 0.0 0.018 15.3 0.0 1.6 2 0 0 2 2 2 1 PPP5 TPR repeat region Lac_bphage_repr PF06543.12 RUS89491.1 - 3.2e-05 23.8 2.0 15 5.6 0.0 6.3 3 2 3 6 6 6 2 Lactococcus bacteriophage repressor SpoU_methylas_C PF12105.8 RUS89491.1 - 0.00036 20.2 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 2 SpoU, rRNA methylase, C-terminal S4 PF01479.25 RUS89491.1 - 0.052 13.3 0.1 22 4.8 0.0 3.9 2 1 2 4 4 4 0 S4 domain Kinin PF08260.11 RUS89491.1 - 3.7 8.4 9.1 1.1e+02 3.9 0.1 5.0 4 0 0 4 4 4 0 Insect kinin peptide Kelch_1 PF01344.25 RUS89492.1 - 4.9e-75 246.9 11.5 1.4e-12 47.0 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 RUS89492.1 - 1.3e-40 136.4 5.7 1.3e-07 31.6 0.0 6.3 3 2 3 6 6 6 6 Kelch motif BTB PF00651.31 RUS89492.1 - 5.9e-31 107.0 0.3 1.1e-30 106.1 0.3 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 RUS89492.1 - 2.8e-29 101.2 0.2 7.8e-29 99.8 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RUS89492.1 - 2.5e-28 97.8 5.9 0.0003 21.0 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS89492.1 - 2.9e-27 94.4 3.4 2.9e-06 27.2 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS89492.1 - 2.2e-23 81.3 2.0 0.00081 19.3 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 RUS89492.1 - 4.5e-11 42.5 8.2 0.039 14.0 0.1 5.6 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 RUS89492.1 - 0.0066 16.6 0.6 1.4 9.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Glyoxal_oxid_N PF07250.11 RUS89492.1 - 0.025 13.8 0.6 0.42 9.8 0.0 2.3 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus zf-C2H2_4 PF13894.6 RUS89493.1 - 1.3e-38 128.3 150.7 0.0037 18.0 2.2 19.5 19 0 0 19 19 19 18 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS89493.1 - 1.1e-36 123.3 155.3 0.001 19.4 1.5 19.5 19 0 0 19 19 19 16 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS89493.1 - 3.2e-16 58.9 137.3 3.4e-07 30.4 1.4 19.5 22 0 0 22 22 22 8 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RUS89493.1 - 1.7e-14 53.7 88.3 0.057 13.7 0.3 17.2 18 0 0 18 18 18 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS89493.1 - 5e-07 29.9 89.4 0.0063 16.9 0.3 16.2 17 0 0 17 17 17 5 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 RUS89493.1 - 0.00061 19.6 6.1 10 6.1 0.0 5.4 4 0 0 4 4 4 2 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 RUS89493.1 - 0.0027 17.7 11.7 0.0077 16.2 3.0 15.8 18 0 0 18 18 18 5 C2H2-type zinc finger HTH_5 PF01022.20 RUS89493.1 - 0.59 10.0 2.3 5.6 6.9 0.2 3.6 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family TRAF6_Z2 PF18048.1 RUS89493.1 - 1.5 9.0 10.7 3.8 7.7 0.1 4.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 eIF3g PF12353.8 RUS89494.1 - 0.03 14.7 0.1 0.03 14.7 0.1 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DUF1759 PF03564.15 RUS89494.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) HutP PF09021.11 RUS89496.1 - 0.18 12.1 2.5 4e+02 1.3 0.0 5.0 1 1 7 8 8 8 0 HutP QVR PF17064.5 RUS89498.1 - 0.00063 19.9 7.7 0.0025 18.0 7.7 1.9 1 1 0 1 1 1 1 Sleepless protein zf-HC5HC2H_2 PF13832.6 RUS89498.1 - 0.012 15.8 3.0 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain GRAM PF02893.20 RUS89499.1 - 1.5e-10 40.9 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 RUS89499.1 - 1.4e-08 34.6 3.5 3.4e-07 30.2 0.0 2.2 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 RUS89499.1 - 0.00028 20.0 0.1 0.099 11.6 0.0 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF639 PF04842.12 RUS89499.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) Reticulon PF02453.17 RUS89499.1 - 0.0047 16.9 2.7 0.12 12.4 0.0 2.6 2 1 0 2 2 2 1 Reticulon Vps36_ESCRT-II PF11605.8 RUS89499.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DMSP_lyase PF16867.5 RUS89499.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF3292 PF11696.8 RUS89499.1 - 0.071 11.5 0.2 1.3 7.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) DUF465 PF04325.13 RUS89501.1 - 0.037 14.1 4.7 0.032 14.2 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF1192 PF06698.11 RUS89501.1 - 1.2 9.3 6.5 8.4 6.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DUF913 PF06025.12 RUS89503.1 - 7.6e-115 383.8 0.1 7.6e-115 383.8 0.1 6.8 8 0 0 8 8 8 1 Domain of Unknown Function (DUF913) HECT PF00632.25 RUS89503.1 - 1.1e-91 307.5 1.1 1.7e-91 306.9 1.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 RUS89503.1 - 4.9e-31 108.4 2.6 4.9e-31 108.4 2.6 6.9 6 2 0 6 6 6 1 Domain of Unknown Function (DUF908) UBM PF14377.6 RUS89503.1 - 3.5e-24 83.4 15.6 2.8e-10 39.3 0.7 4.0 3 0 0 3 3 3 3 Ubiquitin binding region WWE PF02825.20 RUS89503.1 - 5.3e-13 49.4 0.9 1.6e-12 47.8 0.9 1.8 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 RUS89503.1 - 7.6e-10 38.5 0.1 2.2e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain ANF_receptor PF01094.28 RUS89504.1 - 1.1e-66 225.4 0.0 9.1e-33 113.8 0.0 3.1 2 1 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RUS89504.1 - 3.6e-22 79.5 0.0 5.1e-10 39.5 0.1 3.4 3 0 0 3 3 3 3 Periplasmic binding protein AIF_C PF14721.6 RUS89504.1 - 0.12 12.7 0.6 0.57 10.5 0.6 2.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PRIMA1 PF16101.5 RUS89504.1 - 0.28 11.2 6.4 0.097 12.7 0.6 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Laminin_G_3 PF13385.6 RUS89506.1 - 5.5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CXCXC PF03128.14 RUS89506.1 - 0.0028 18.0 1.4 0.48 11.0 0.2 3.1 2 0 0 2 2 2 1 CXCXC repeat CBM_14 PF01607.24 RUS89506.1 - 0.0093 16.1 5.3 0.099 12.8 1.9 2.7 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Laminin_G_2 PF02210.24 RUS89506.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain ANF_receptor PF01094.28 RUS89507.1 - 3.8e-62 210.4 0.0 6.4e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 RUS89507.1 - 3.4e-40 138.0 0.0 5.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89507.1 - 5.3e-32 111.2 0.0 1.2e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 RUS89507.1 - 7.1e-25 87.7 0.4 4.2e-23 81.9 0.2 2.3 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS89507.1 - 0.00083 18.8 0.4 0.0016 17.9 0.4 1.4 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.6 RUS89507.1 - 0.019 14.6 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein XPB_DRD PF18458.1 RUS89507.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain PA28_alpha PF02251.18 RUS89507.1 - 0.17 12.0 0.4 3.1 7.9 0.3 2.4 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit S1FA PF04689.13 RUS89507.1 - 3.2 8.0 4.2 7 6.9 4.2 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA ANF_receptor PF01094.28 RUS89508.1 - 8.3e-21 74.5 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ANF_receptor PF01094.28 RUS89509.1 - 3.8e-17 62.4 0.0 4.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region VIT PF08487.10 RUS89511.1 - 1e-29 103.0 0.7 2.5e-29 101.7 0.7 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 RUS89511.1 - 5.3e-20 72.4 1.0 5.3e-20 72.4 1.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS89511.1 - 5.8e-19 68.5 0.0 1.1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS89511.1 - 5.1e-14 52.8 0.1 1.5e-13 51.3 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS89511.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 RUS89511.1 - 0.00082 19.5 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Peptidase_S49_N PF08496.10 RUS89511.1 - 0.014 15.5 0.0 0.014 15.5 0.0 3.4 5 0 0 5 5 5 0 Peptidase family S49 N-terminal ANF_receptor PF01094.28 RUS89513.1 - 2.3e-13 50.0 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Reticulon PF02453.17 RUS89514.1 - 4.2e-46 156.8 6.4 6.2e-46 156.2 6.4 1.3 1 0 0 1 1 1 1 Reticulon DUF4736 PF15883.5 RUS89514.1 - 0.089 12.5 1.0 0.17 11.6 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) WD40 PF00400.32 RUS89515.1 - 3.6e-08 33.9 7.9 0.0027 18.5 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS89515.1 - 0.0078 16.5 0.0 0.23 11.8 0.0 3.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 RUS89515.1 - 0.045 12.8 0.1 2.5 7.1 0.0 2.7 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 eIF2A PF08662.11 RUS89515.1 - 0.13 12.1 0.2 25 4.7 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Med6 PF04934.14 RUS89516.1 - 2.3e-45 153.7 0.0 3.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component TMEM72 PF16054.5 RUS89517.1 - 3e-23 82.5 6.2 3.9e-23 82.1 6.2 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 cNMP_binding PF00027.29 RUS89518.1 - 1.1e-17 63.8 0.5 6.9e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Spore_coat_CotO PF14153.6 RUS89518.1 - 0.02 14.9 5.8 0.15 12.0 0.2 2.6 2 0 0 2 2 2 0 Spore coat protein CotO Glycoprotein PF03409.15 RUS89518.1 - 0.11 11.3 2.8 0.2 10.5 2.8 1.3 1 0 0 1 1 1 0 Transmembrane glycoprotein Metallophos PF00149.28 RUS89519.1 - 2.4e-09 38.0 1.1 4.7e-09 37.0 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Big_7 PF17957.1 RUS89519.1 - 0.0045 17.7 0.0 0.015 16.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial Ig domain Metallophos_2 PF12850.7 RUS89519.1 - 0.013 15.7 0.2 0.088 13.0 0.2 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Memo PF01875.17 RUS89520.1 - 6.6e-85 284.5 0.0 7.5e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Homeobox_KN PF05920.11 RUS89521.1 - 9e-17 60.7 0.2 1.3e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RUS89521.1 - 1.5e-07 31.2 0.1 2.2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Homeodomain Meis_PKNOX_N PF16493.5 RUS89523.1 - 1.8e-43 146.7 0.5 3.4e-43 145.9 0.5 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 RRN3 PF05327.11 RUS89524.1 - 5.9e-05 21.8 14.6 6.1e-05 21.8 14.6 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 RUS89524.1 - 0.0048 16.4 16.7 0.0054 16.2 16.7 1.1 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 RUS89524.1 - 0.062 11.7 13.3 0.073 11.5 13.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 RUS89524.1 - 0.23 9.7 17.2 0.3 9.3 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 RUS89524.1 - 0.41 10.4 12.6 0.61 9.8 12.6 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CobT PF06213.12 RUS89524.1 - 1.2 8.5 17.3 1.7 8.0 17.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2428 PF10350.9 RUS89524.1 - 2.6 7.2 4.2 3.4 6.8 4.2 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) TRAP_alpha PF03896.16 RUS89524.1 - 3.4 6.8 13.2 4.5 6.4 13.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 RUS89524.1 - 3.8 7.0 19.6 5.5 6.5 19.6 1.3 1 0 0 1 1 1 0 PPP4R2 TNF PF00229.18 RUS89525.1 - 3.5e-15 56.1 0.0 8.2e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 RUS89525.1 - 0.064 13.5 0.5 0.42 10.8 0.5 2.1 1 1 0 1 1 1 0 C1q domain LIM PF00412.22 RUS89526.1 - 6.4e-57 189.6 68.9 2.9e-14 53.0 7.6 5.1 5 0 0 5 5 5 5 LIM domain DUF732 PF05305.14 RUS89526.1 - 0.22 11.9 2.2 0.92 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Ank_2 PF12796.7 RUS89527.1 - 2.9e-17 63.0 3.7 2.2e-12 47.4 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS89527.1 - 3.2e-14 53.1 2.4 7.2e-05 23.3 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89527.1 - 1.4e-12 46.6 1.4 0.18 12.4 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 RUS89527.1 - 1.8e-10 40.9 4.2 2.6e-07 30.8 0.3 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS89527.1 - 1e-09 38.4 5.7 0.21 12.1 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Wound_ind PF08186.11 RUS89527.1 - 0.11 13.0 2.0 0.19 12.2 2.0 1.4 1 0 0 1 1 1 0 Wound-inducible basic protein family Filamin PF00630.19 RUS89528.1 - 5.5e-62 207.0 1.9 4.3e-13 50.0 0.0 7.7 7 0 0 7 7 7 7 Filamin/ABP280 repeat CH PF00307.31 RUS89528.1 - 7.4e-55 183.8 0.2 1.2e-20 73.7 0.3 3.2 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RUS89528.1 - 2.4e-10 40.1 0.0 0.0057 16.5 0.0 3.5 3 0 0 3 3 3 3 CAMSAP CH domain Big_3_5 PF16640.5 RUS89528.1 - 0.00052 20.1 2.5 1.8 8.8 0.0 4.8 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 3) DUF5060 PF16586.5 RUS89528.1 - 0.056 13.8 0.1 17 5.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5060) DUF885 PF05960.11 RUS89529.1 - 1e-85 289.4 0.0 1.3e-45 157.1 0.1 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF885) FidL_like PF15941.5 RUS89529.1 - 1.2 9.6 4.2 29 5.2 0.2 3.1 3 0 0 3 3 3 0 FidL-like putative membrane protein Cadherin PF00028.17 RUS89530.1 - 1.4e-95 313.9 7.4 1.3e-16 60.8 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS89530.1 - 3.1e-16 59.0 2.2 2.3e-12 46.6 0.0 4.9 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 RUS89530.1 - 3.3e-09 36.7 10.4 0.027 14.5 0.0 6.1 6 1 0 6 6 6 3 Cadherin-like Cadherin_pro PF08758.11 RUS89530.1 - 0.022 14.9 0.1 2 8.6 0.0 3.7 4 0 0 4 4 4 0 Cadherin prodomain like Sigma_reg_N PF13800.6 RUS89530.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ETRAMP PF09716.10 RUS89530.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PAS_3 PF08447.12 RUS89532.1 - 1.2e-23 83.2 0.0 7.3e-16 58.2 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 RUS89532.1 - 6.4e-20 71.4 0.0 6.4e-20 71.4 0.0 4.5 5 0 0 5 5 5 2 PAS domain HLH PF00010.26 RUS89532.1 - 2.6e-09 36.9 1.9 6.4e-09 35.6 1.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 RUS89532.1 - 2.1e-08 34.1 0.0 2e-08 34.2 0.0 4.7 6 0 0 6 6 6 2 PAS fold PAS_4 PF08448.10 RUS89532.1 - 0.00017 21.8 0.0 0.0044 17.3 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 RUS89532.1 - 0.00084 19.6 0.0 0.0044 17.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain Med26 PF08711.11 RUS89532.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Ank_2 PF12796.7 RUS89533.1 - 7.2e-26 90.6 10.0 5.3e-08 33.3 1.0 3.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS89533.1 - 5.5e-20 71.5 3.0 4.8e-06 27.0 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89533.1 - 5e-17 60.3 0.1 0.0027 18.0 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RUS89533.1 - 8.5e-17 61.0 1.1 1.6e-05 25.1 0.0 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS89533.1 - 2.7e-16 59.2 5.4 0.00062 20.1 0.0 6.9 7 1 0 7 7 7 3 Ankyrin repeat UPF0180 PF03698.13 RUS89533.1 - 0.0005 20.2 0.8 0.22 11.7 0.1 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0180) Phage_T7_Capsid PF05396.11 RUS89533.1 - 0.078 13.3 0.1 11 6.4 0.0 2.7 3 0 0 3 3 3 0 Phage T7 capsid assembly protein Neur_chan_LBD PF02931.23 RUS89534.1 - 4.3e-33 114.6 1.4 6.4e-33 114.0 1.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS89534.1 - 1.4e-12 48.2 11.0 2.8e-11 43.9 2.0 2.9 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 RUS89534.1 - 0.0018 16.5 37.8 0.0026 16.0 37.8 1.1 1 0 0 1 1 1 1 DNA polymerase phi Mpp10 PF04006.12 RUS89534.1 - 0.003 16.1 11.4 0.004 15.7 11.4 1.1 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 RUS89534.1 - 0.02 13.1 23.4 0.028 12.6 23.4 1.2 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 RUS89534.1 - 0.034 14.0 0.4 0.05 13.4 0.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 RUS89534.1 - 0.068 13.2 24.7 0.09 12.8 24.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 RUS89534.1 - 0.075 11.8 1.1 0.096 11.5 1.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.12 RUS89534.1 - 0.3 9.4 6.3 0.49 8.7 6.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 RUS89534.1 - 0.96 8.8 27.3 1.6 8.1 27.3 1.2 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 RUS89534.1 - 2.4 7.9 13.2 6.3 6.5 13.2 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH ERM PF00769.19 RUS89535.1 - 1.1e-42 146.6 50.9 1.6e-42 146.1 50.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family FERM_M PF00373.18 RUS89535.1 - 6e-23 81.5 0.2 6e-23 81.5 0.2 3.5 3 1 0 3 3 3 1 FERM central domain FERM_C PF09380.10 RUS89535.1 - 3.1e-18 65.9 0.0 8.7e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 RUS89535.1 - 3.7e-15 55.6 1.0 1.1e-14 54.1 0.1 2.4 3 0 0 3 3 3 1 FERM N-terminal domain ACBP PF00887.19 RUS89535.1 - 0.0089 16.2 1.6 0.025 14.8 0.0 2.5 3 0 0 3 3 3 1 Acyl CoA binding protein BLOC1_2 PF10046.9 RUS89535.1 - 8 6.8 19.4 1 9.7 6.3 3.6 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DDE_Tnp_1_7 PF13843.6 RUS89536.1 - 1.1e-10 41.3 0.5 7.9e-05 22.1 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 Orthopox_F8 PF05886.11 RUS89536.1 - 0.13 12.4 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Orthopoxvirus F8 protein FYVE PF01363.21 RUS89537.1 - 0.17 12.0 4.7 9.4 6.5 0.8 2.6 2 0 0 2 2 2 0 FYVE zinc finger Spem1 PF15670.5 RUS89537.1 - 5.9 6.4 8.1 0.46 10.0 0.5 2.5 2 1 1 3 3 3 0 Spermatid maturation protein 1 Ank_2 PF12796.7 RUS89539.1 - 4.8e-22 78.3 4.4 6.6e-08 33.0 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS89539.1 - 1.1e-20 73.7 7.3 8.7e-06 26.2 0.2 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS89539.1 - 2.7e-13 49.9 10.3 2.9e-07 30.6 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS89539.1 - 4.1e-13 49.1 7.2 0.00031 21.0 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 RUS89539.1 - 5.4e-11 41.7 5.7 0.018 15.5 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat CH PF00307.31 RUS89539.1 - 7e-07 29.4 0.2 3.1e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain Aldolase_II PF00596.21 RUS89541.1 - 4.9e-41 140.7 0.0 5.8e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ephrin_rec_like PF07699.13 RUS89543.1 - 3.2e-23 81.2 16.9 3.5e-14 52.3 4.9 2.5 2 0 0 2 2 2 2 Putative ephrin-receptor like CUB PF00431.20 RUS89543.1 - 5.6e-16 58.8 0.0 9.1e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 CUB domain TNFR_c6 PF00020.18 RUS89543.1 - 0.39 11.2 12.8 1.7 9.1 0.8 3.9 2 2 2 4 4 4 0 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 RUS89543.1 - 4.2 7.5 8.0 2 8.6 1.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) FXa_inhibition PF14670.6 RUS89544.1 - 2.4e-37 126.9 115.4 2.1e-09 37.5 12.5 9.0 8 1 1 9 9 9 6 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS89544.1 - 1.3e-31 108.1 61.6 7.2e-09 35.4 1.5 8.4 8 0 0 8 8 8 6 Complement Clr-like EGF-like EGF_CA PF07645.15 RUS89544.1 - 5e-19 68.2 93.9 5.8e-09 36.0 8.7 7.9 7 1 0 7 7 7 4 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 RUS89544.1 - 7e-11 41.7 5.5 7e-11 41.7 5.5 4.6 4 1 1 5 5 5 1 Putative ephrin-receptor like EGF PF00008.27 RUS89544.1 - 2.8e-08 33.9 74.5 0.012 15.9 5.2 7.6 6 0 0 6 6 6 5 EGF-like domain EGF_3 PF12947.7 RUS89544.1 - 2.8e-07 30.6 82.3 0.0058 16.8 4.1 8.4 6 1 1 7 7 7 5 EGF domain hEGF PF12661.7 RUS89544.1 - 6.7e-05 23.4 61.7 0.11 13.1 4.8 8.4 6 2 0 6 6 6 5 Human growth factor-like EGF GTP_cyclohydroI PF01227.22 RUS89544.1 - 0.069 12.6 0.6 0.21 11.0 0.3 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase I RE_EcoO109I PF14511.6 RUS89544.1 - 0.076 12.6 0.5 0.15 11.7 0.3 1.4 1 1 0 1 1 1 0 Type II restriction endonuclease EcoO109I EGF_3 PF12947.7 RUS89546.1 - 2.1e-11 43.8 28.0 4.2e-08 33.3 7.2 2.4 2 0 0 2 2 2 2 EGF domain cEGF PF12662.7 RUS89546.1 - 3.3e-11 42.9 15.9 7.8e-07 28.9 1.3 3.1 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 RUS89546.1 - 6.1e-10 39.2 27.4 1.3e-09 38.1 11.8 2.5 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 RUS89546.1 - 1.9e-06 28.0 26.8 3.7e-05 23.8 12.3 2.3 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 RUS89546.1 - 4.3e-05 23.7 20.6 0.00067 19.9 4.2 3.0 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 RUS89546.1 - 0.0001 22.8 10.3 0.059 14.0 0.4 3.3 2 1 0 2 2 2 2 Human growth factor-like EGF DUF1687 PF07955.11 RUS89546.1 - 0.21 12.0 0.5 1.7 9.1 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) Plasmod_Pvs28 PF06247.11 RUS89546.1 - 0.27 11.6 19.8 22 5.5 6.8 2.8 1 1 1 2 2 2 0 Pvs28 EGF domain YidD PF01809.18 RUS89547.1 - 0.054 13.4 0.1 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor FAM198 PF15051.6 RUS89549.1 - 0.01 14.7 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 FAM198 protein Fam20C PF06702.12 RUS89549.1 - 0.012 15.5 1.8 1 9.1 0.4 2.8 2 1 0 3 3 3 0 Golgi casein kinase, C-terminal, Fam20 EF-hand_1 PF00036.32 RUS89550.1 - 6.8e-24 81.6 13.1 4.3e-05 22.7 0.0 5.8 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 RUS89550.1 - 1.6e-22 79.8 20.6 2.5e-11 43.9 3.5 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS89550.1 - 1.1e-20 72.1 23.2 1.6e-05 24.1 0.7 5.6 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 RUS89550.1 - 4.3e-20 69.9 11.5 0.00072 19.3 0.0 6.0 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 RUS89550.1 - 7.5e-09 35.3 11.7 0.33 10.8 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_10 PF14788.6 RUS89550.1 - 0.0004 20.2 4.6 1.2 9.0 0.1 4.1 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 RUS89550.1 - 0.0011 19.3 17.2 0.019 15.3 3.0 3.5 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Spa1_C PF18218.1 RUS89550.1 - 0.023 15.1 0.1 0.092 13.2 0.1 2.1 1 1 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain DUF3579 PF12112.8 RUS89550.1 - 0.11 13.1 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) FumaraseC_C PF10415.9 RUS89550.1 - 0.2 12.1 0.6 1e+02 3.4 0.0 3.5 3 0 0 3 3 3 0 Fumarase C C-terminus DUF327 PF03885.13 RUS89550.1 - 0.34 10.9 2.5 4.6 7.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF327) MFS_1 PF07690.16 RUS89551.1 - 1.4e-13 50.6 51.8 2.3e-09 36.7 14.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily PrgI PF12666.7 RUS89551.1 - 0.7 10.6 0.1 0.7 10.6 0.1 5.3 5 2 1 6 6 6 0 PrgI family protein DUF3552 PF12072.8 RUS89552.1 - 2.1e-05 24.1 13.3 0.0095 15.4 4.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Bep_C_terminal PF17841.1 RUS89552.1 - 0.08 13.2 7.3 2.8 8.2 1.7 2.7 1 1 1 2 2 2 0 BID domain of Bartonella effector protein (Bep) Occludin_ELL PF07303.13 RUS89552.1 - 3.9 8.2 7.7 19 6.1 1.6 2.1 1 1 1 2 2 2 0 Occludin homology domain F-box PF00646.33 RUS89553.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS89553.1 - 0.0019 18.0 0.0 0.0077 16.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 RUS89553.1 - 0.035 14.4 0.2 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 PRANC domain DUF3134 PF11332.8 RUS89553.1 - 0.19 12.1 0.1 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) RFX_DNA_binding PF02257.15 RUS89555.1 - 4.2e-31 107.4 0.2 9.2e-31 106.3 0.2 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain DUF1979 PF09322.10 RUS89556.1 - 0.13 12.1 0.1 71 3.4 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1979) VPS28 PF03997.12 RUS89556.1 - 0.57 9.8 2.5 23 4.6 0.0 2.8 2 1 1 3 3 3 0 VPS28 protein WSC PF01822.19 RUS89557.1 - 4.7e-06 26.7 0.6 4.7e-06 26.7 0.6 2.2 2 1 0 2 2 2 1 WSC domain Utp14 PF04615.13 RUS89558.1 - 0.14 10.7 15.0 0.21 10.1 15.0 1.2 1 0 0 1 1 1 0 Utp14 protein Membralin PF09746.9 RUS89558.1 - 2.9 6.8 10.7 5 6.1 10.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein PI3K_1B_p101 PF10486.9 RUS89558.1 - 9 3.9 9.9 13 3.4 9.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CBM_14 PF01607.24 RUS89559.1 - 0.0029 17.7 0.2 0.0077 16.4 0.2 1.8 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Shisa PF13908.6 RUS89559.1 - 0.72 10.1 8.2 1.2 9.4 8.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.25 RUS89560.1 - 8.2e-10 38.9 0.1 1.1e-09 38.5 0.1 1.1 1 0 0 1 1 1 1 F5/8 type C domain XRCC4 PF06632.12 RUS89561.1 - 2.9e-42 144.7 14.3 9.9e-42 143.0 14.3 1.7 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 IKBKB_SDD PF18397.1 RUS89561.1 - 0.0046 16.3 1.4 0.0046 16.3 1.4 1.4 2 0 0 2 2 2 1 IQBAL scaffold dimerization domain KASH_CCD PF14662.6 RUS89561.1 - 0.0057 16.5 4.5 0.013 15.3 4.5 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SNAD3 PF18749.1 RUS89561.1 - 0.026 13.7 0.5 0.041 13.0 0.5 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 DivIC PF04977.15 RUS89561.1 - 0.048 13.4 2.5 0.067 13.0 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4686 PF15742.5 RUS89561.1 - 0.12 11.5 11.7 0.025 13.7 1.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Stathmin PF00836.19 RUS89561.1 - 0.19 11.7 5.7 3.8 7.5 5.7 2.6 1 1 0 1 1 1 0 Stathmin family DUF5595 PF18077.1 RUS89561.1 - 1.7 8.8 5.1 8.6 6.5 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Pkinase PF00069.25 RUS89563.1 - 3.6e-27 95.4 0.0 1.1e-26 93.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89563.1 - 5.7e-11 42.2 0.0 7.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS89563.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DNA_pol_B_thumb PF14791.6 RUS89564.1 - 1.3e-21 76.5 0.0 2.7e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 RUS89564.1 - 7.7e-13 48.6 0.0 7.9e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 RUS89564.1 - 1.3e-11 44.7 0.0 1e-10 41.8 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 RUS89564.1 - 1e-10 41.3 0.0 3.8e-10 39.4 0.0 2.1 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 RUS89564.1 - 0.0016 18.8 0.1 0.0029 18.0 0.1 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 RUS89564.1 - 0.0033 17.3 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 RUS89564.1 - 0.0086 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RUS89564.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BTB PF00651.31 RUS89565.1 - 1e-16 61.2 0.8 2.2e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 RUS89565.1 - 3e-13 49.7 0.0 7.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 RUS89566.1 - 0.066 13.3 0.0 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 F5/8 type C domain Cadherin_C_2 PF16492.5 RUS89567.1 - 0.087 13.6 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Laminin_EGF PF00053.24 RUS89567.1 - 0.29 11.3 52.5 0.72 10.0 15.5 4.4 1 1 3 4 4 4 0 Laminin EGF domain Y_phosphatase PF00102.27 RUS89568.1 - 1.7e-12 47.4 0.0 2.2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gp49 PF05973.14 RUS89568.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Y_phosphatase PF00102.27 RUS89569.1 - 1.7e-71 240.5 0.0 3.8e-67 226.3 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Laminin_EGF PF00053.24 RUS89569.1 - 3.9e-06 26.9 82.5 1.2 9.4 24.0 5.4 1 1 4 5 5 5 3 Laminin EGF domain DSPc PF00782.20 RUS89569.1 - 0.00089 19.1 0.0 0.0024 17.7 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RUS89569.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 RUS89569.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate EphA2_TM PF14575.6 RUS89569.1 - 0.033 15.1 0.0 0.083 13.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 RUS89569.1 - 0.046 13.7 0.7 0.094 12.7 0.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J F5_F8_type_C PF00754.25 RUS89570.1 - 0.025 14.7 1.5 2.3 8.3 0.0 2.4 2 1 0 2 2 2 0 F5/8 type C domain LTV PF04180.14 RUS89571.1 - 3e-08 33.8 38.3 1.8e-05 24.7 28.7 3.1 2 1 0 2 2 2 2 Low temperature viability protein UPF0767 PF15990.5 RUS89571.1 - 1 9.5 5.0 0.74 10.0 2.3 2.2 2 0 0 2 2 2 0 UPF0767 family DNA_repr_REX1B PF14966.6 RUS89572.1 - 5.4e-25 87.9 3.0 1.1e-24 86.9 1.2 1.9 2 0 0 2 2 2 1 DNA repair REX1-B Latrophilin PF02354.16 RUS89572.1 - 0.06 12.4 0.3 0.074 12.1 0.3 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region DUF3347 PF11827.8 RUS89572.1 - 0.12 12.5 1.5 0.16 12.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF948 PF06103.11 RUS89572.1 - 0.23 11.8 1.1 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GvpL_GvpF PF06386.11 RUS89572.1 - 0.3 11.0 3.0 0.42 10.5 2.7 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF YabA PF06156.13 RUS89572.1 - 0.69 10.6 4.7 1.9 9.1 1.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 RUS89572.1 - 1.9 8.9 7.3 2.1 8.8 1.9 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 RUS89572.1 - 2 8.5 4.4 3.7 7.6 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) C2 PF00168.30 RUS89573.1 - 4.5e-08 33.3 0.0 8.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain LZ_Tnp_IS66 PF13007.7 RUS89573.1 - 0.4 11.5 0.1 0.4 11.5 0.1 4.8 4 0 0 4 4 4 0 Transposase C of IS166 homeodomain DUF1771 PF08590.10 RUS89573.1 - 0.9 10.0 8.7 0.54 10.7 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TarH PF02203.15 RUS89573.1 - 3.8 7.4 7.2 0.29 11.1 0.5 2.6 3 0 0 3 3 3 0 Tar ligand binding domain homologue 7tm_1 PF00001.21 RUS89574.1 - 1.6e-31 109.6 7.7 1.8e-31 109.4 7.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS89574.1 - 5.3e-07 29.5 7.8 6.9e-07 29.2 7.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRRC37AB_C PF14914.6 RUS89574.1 - 0.25 11.2 2.5 4.5 7.2 0.1 2.2 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF4389 PF14333.6 RUS89574.1 - 0.72 9.8 9.7 5.4 7.0 2.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) FAM176 PF14851.6 RUS89574.1 - 0.8 9.4 2.9 0.59 9.8 0.3 2.1 2 1 0 2 2 2 0 FAM176 family DERM PF14704.6 RUS89575.1 - 4.1e-34 118.3 1.3 5.5e-34 117.8 1.3 1.1 1 0 0 1 1 1 1 Dermatopontin DUF5122 PF17164.4 RUS89575.1 - 0.049 13.9 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Adap_comp_sub PF00928.21 RUS89577.1 - 1.2e-92 310.1 0.7 1.2e-92 310.1 0.7 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS89577.1 - 5.1e-08 33.0 3.9 9.6e-08 32.1 3.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 RUS89577.1 - 0.0033 17.4 0.2 0.0098 15.9 0.1 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF1359 PF07097.11 RUS89577.1 - 0.044 14.0 0.1 0.09 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) muHD PF10291.9 RUS89577.1 - 0.055 12.9 0.2 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain ADH_N PF08240.12 RUS89578.1 - 2.2e-23 82.2 4.1 3.5e-23 81.6 4.1 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain V-SNARE_C PF12352.8 RUS89579.1 - 2.2e-19 69.5 6.0 1.8e-18 66.5 5.5 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 RUS89579.1 - 4.6e-18 65.4 2.9 4.6e-18 65.4 2.9 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF241 PF03087.14 RUS89579.1 - 0.0086 15.9 0.3 0.0086 15.9 0.3 2.6 1 1 2 3 3 3 1 Arabidopsis protein of unknown function Sec20 PF03908.13 RUS89579.1 - 0.027 14.4 4.3 0.073 13.0 0.2 2.7 2 1 1 3 3 3 0 Sec20 RapH_N PF18801.1 RUS89579.1 - 0.087 12.9 1.3 0.22 11.7 1.3 1.6 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Snapin_Pallidin PF14712.6 RUS89579.1 - 0.2 12.1 8.6 4 7.9 3.6 2.4 2 0 0 2 2 2 0 Snapin/Pallidin YqjK PF13997.6 RUS89579.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.5 2 1 0 2 2 2 0 YqjK-like protein Syntaxin-6_N PF09177.11 RUS89579.1 - 0.95 10.1 9.1 28 5.4 9.1 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PBP_sp32 PF07222.12 RUS89579.1 - 1.9 7.9 5.2 1.1 8.7 3.2 1.6 1 1 1 2 2 2 0 Proacrosin binding protein sp32 DUF948 PF06103.11 RUS89579.1 - 3.5 8.0 6.0 4.6 7.6 2.0 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 RUS89579.1 - 4.6 6.7 12.4 27 4.2 12.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 RUS89579.1 - 8 7.1 8.0 1.8 9.2 0.9 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ank_4 PF13637.6 RUS89580.1 - 4.3e-152 492.7 55.0 2e-12 47.4 0.0 16.1 3 3 17 21 21 21 20 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS89580.1 - 4.4e-150 488.7 43.6 2.7e-18 66.3 0.6 12.2 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 RUS89580.1 - 6.2e-139 447.0 57.2 1.2e-07 31.9 0.1 23.2 22 1 1 23 23 23 21 Ankyrin repeat Ank_5 PF13857.6 RUS89580.1 - 1.4e-128 417.3 40.9 3.6e-12 46.3 0.3 17.9 3 3 15 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89580.1 - 5.2e-120 376.7 30.9 1.1e-05 25.4 0.0 23.7 24 0 0 24 24 24 21 Ankyrin repeat PK_C PF02887.16 RUS89580.1 - 3.5e-05 24.0 0.3 0.71 10.1 0.0 4.5 4 2 0 4 4 4 2 Pyruvate kinase, alpha/beta domain Shigella_OspC PF06128.11 RUS89580.1 - 0.088 12.5 0.1 15 5.2 0.0 3.7 5 0 0 5 5 5 0 Shigella flexneri OspC protein EST1 PF10374.9 RUS89582.1 - 4.1e-05 24.2 2.9 0.031 14.9 0.9 3.6 1 1 1 2 2 2 2 Telomerase activating protein Est1 HEAT_UF PF18817.1 RUS89582.1 - 0.0002 21.6 27.5 0.17 12.2 0.5 6.3 1 1 8 9 9 9 5 Repeat of uncharacterized protein PH0542 Phasin_2 PF09361.10 RUS89582.1 - 0.00045 20.4 2.1 3 8.1 0.1 3.7 1 1 2 3 3 3 2 Phasin protein DUF5132 PF17195.4 RUS89582.1 - 0.00058 19.9 16.6 74 3.5 0.3 10.2 1 1 7 9 9 9 0 Protein of unknown function (DUF5132) DUF2621 PF11084.8 RUS89582.1 - 0.00086 19.3 6.7 19 5.2 0.3 5.5 1 1 4 5 5 5 0 Protein of unknown function (DUF2621) RSS_P20 PF11757.8 RUS89582.1 - 0.017 15.5 13.5 7.8 7.0 1.1 4.5 1 1 4 5 5 5 0 Suppressor of RNA silencing P21-like N-terminal domain DBINO PF13892.6 RUS89582.1 - 0.018 15.4 3.2 4 7.8 0.2 2.7 1 1 2 3 3 3 0 DNA-binding domain Adeno_E1B_19K PF01691.16 RUS89582.1 - 0.23 11.0 10.8 0.41 10.2 1.2 3.4 1 1 2 3 3 3 0 Adenovirus E1B 19K protein / small t-antigen RepA_C PF04796.12 RUS89582.1 - 0.39 10.7 2.5 50 3.9 0.2 3.2 1 1 2 3 3 3 0 Plasmid encoded RepA protein Rhabdo_ncap_2 PF03216.13 RUS89582.1 - 0.53 9.7 9.4 1.7 8.0 1.2 3.0 1 1 2 3 3 3 0 Rhabdovirus nucleoprotein PI3_PI4_kinase PF00454.27 RUS89582.1 - 0.68 9.7 3.4 32 4.2 0.1 3.4 1 1 2 4 4 4 0 Phosphatidylinositol 3- and 4-kinase zf-C4 PF00105.18 RUS89585.1 - 1.8e-21 76.3 12.8 3e-21 75.7 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS89585.1 - 3.5e-12 46.3 0.6 6.1e-12 45.6 0.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 RUS89585.1 - 0.13 12.4 4.4 0.31 11.2 4.4 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C3HC4_3 PF13920.6 RUS89586.1 - 1.7e-14 53.4 10.9 3.2e-14 52.5 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS89586.1 - 7.5e-05 22.5 9.9 0.00015 21.6 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 RUS89586.1 - 0.00014 21.6 12.9 0.00028 20.7 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS89586.1 - 0.00025 21.3 12.8 0.0005 20.3 12.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS89586.1 - 0.025 14.5 11.8 0.049 13.6 11.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF1640 PF07798.11 RUS89586.1 - 0.15 12.1 5.6 1.9 8.5 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 RUS89586.1 - 0.55 10.4 0.1 0.55 10.4 0.1 2.5 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 Rad50_zn_hook PF04423.14 RUS89586.1 - 0.67 9.8 4.4 8 6.4 0.3 2.7 1 1 1 2 2 2 0 Rad50 zinc hook motif Med24_N PF11277.8 RUS89587.1 - 1.1e-188 629.5 18.3 1.4e-188 629.2 18.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal ExbD PF02472.16 RUS89587.1 - 0.013 15.7 0.1 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR MukF_C PF17193.4 RUS89587.1 - 0.057 13.6 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 MukF C-terminal domain B12-binding_2 PF02607.17 RUS89587.1 - 0.36 11.3 2.1 5.7 7.4 0.1 2.9 2 1 0 2 2 2 0 B12 binding domain CARD PF00619.21 RUS89589.1 - 7.1e-16 58.0 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 RUS89589.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD PF00619.21 RUS89590.1 - 1.8e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CENP-H PF05837.12 RUS89591.1 - 0.037 14.4 1.1 0.11 13.0 1.1 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2680 PF10925.8 RUS89591.1 - 0.04 13.9 0.7 0.085 12.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Ead_Ea22 PF13935.6 RUS89591.1 - 0.092 13.4 0.1 0.25 12.0 0.1 1.7 1 0 0 1 1 1 0 Ead/Ea22-like protein GAS PF13851.6 RUS89591.1 - 1.3 8.3 8.6 0.24 10.7 2.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2408 PF10303.9 RUS89591.1 - 1.3 9.5 6.4 2.4 8.7 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) APG6_N PF17675.1 RUS89591.1 - 4.8 7.7 10.5 17 5.9 10.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region PigN PF04987.14 RUS89593.1 - 1.5e-121 406.4 47.0 2.2e-121 405.9 47.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RUS89593.1 - 8.8e-12 45.3 0.4 3.5e-10 40.0 0.4 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS89593.1 - 1.4e-06 27.9 0.1 2.4e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RUS89593.1 - 2.1e-05 24.0 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 RUS89593.1 - 0.21 10.5 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase MFS_1 PF07690.16 RUS89594.1 - 5.3e-28 97.9 23.4 7.6e-28 97.4 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 RUS89594.1 - 2.3e-05 22.9 0.2 2.3e-05 22.9 0.2 2.0 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Transgly_assoc PF04226.13 RUS89594.1 - 0.021 15.1 3.1 0.038 14.3 0.3 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein DUF21 PF01595.20 RUS89594.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.3 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Hexokinase_2 PF03727.16 RUS89595.1 - 5.8e-85 284.5 0.0 7.8e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RUS89595.1 - 6.8e-64 215.4 0.0 1e-63 214.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase ADP_ribosyl_GH PF03747.14 RUS89596.1 - 6e-32 111.5 0.2 1.1e-31 110.6 0.2 1.5 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_8 PF13855.6 RUS89596.1 - 3.8e-16 58.6 9.1 2.7e-09 36.7 2.6 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS89596.1 - 1.7e-10 40.9 4.6 4.2e-05 23.8 0.9 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RUS89596.1 - 0.0012 18.7 6.0 0.77 10.0 0.2 4.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 RUS89596.1 - 0.0025 18.1 8.0 5.7 7.9 0.8 4.7 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 RUS89596.1 - 0.0041 16.6 0.4 0.1 12.1 0.2 2.4 1 1 1 2 2 2 1 Leucine-rich repeat WGG PF10273.9 RUS89597.1 - 9.6e-26 90.3 0.6 1.9e-25 89.3 0.6 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 WH1 PF00568.23 RUS89598.1 - 5.4e-37 126.1 1.0 7.7e-37 125.6 1.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 RUS89598.1 - 4.9e-14 52.4 1.0 1.1e-13 51.3 0.1 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain AflR PF08493.10 RUS89598.1 - 0.079 12.4 0.6 0.11 11.9 0.6 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Ras PF00071.22 RUS89599.1 - 9e-63 210.7 0.0 7.8e-56 188.1 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RUS89599.1 - 7e-24 84.4 0.0 1e-21 77.4 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS89599.1 - 5.6e-11 42.2 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family DivIC PF04977.15 RUS89599.1 - 0.0041 16.9 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 2 Septum formation initiator SRPRB PF09439.10 RUS89599.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pdase_M17_N2 PF18295.1 RUS89599.1 - 0.13 12.5 0.2 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 CBFD_NFYB_HMF PF00808.23 RUS89600.1 - 1.9e-29 101.7 0.5 3.2e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RUS89600.1 - 2.3e-08 34.5 0.0 5.3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RUS89600.1 - 0.0012 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 RUS89600.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 RUS89600.1 - 0.036 14.6 0.5 0.1 13.1 0.0 1.9 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 RUS89600.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated DUF5126 PF17166.4 RUS89602.1 - 0.081 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Exo_endo_phos PF03372.23 RUS89603.1 - 0.00042 19.9 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L10 PF00466.20 RUS89603.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L10 Exo_endo_phos PF03372.23 RUS89604.1 - 0.00014 21.4 0.1 0.00016 21.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.31 RUS89606.1 - 4e-21 75.3 0.4 1.5e-20 73.4 0.2 2.0 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 RUS89606.1 - 2.4e-16 59.0 9.1 2.1e-05 24.0 0.1 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 RUS89606.1 - 6.6e-15 54.4 2.6 1.9e-06 27.6 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 RUS89606.1 - 1.2e-12 47.7 8.5 0.0029 17.8 0.3 4.4 3 1 1 4 4 4 3 Galactose oxidase, central domain BACK PF07707.15 RUS89606.1 - 2e-11 43.9 0.0 4.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS89606.1 - 5.7e-11 42.3 3.6 6.7e-05 23.0 0.1 5.1 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 RUS89606.1 - 1.7e-10 40.8 3.1 8.4e-07 28.9 0.0 4.0 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS89606.1 - 3.2e-08 33.4 6.2 0.00021 21.2 0.1 4.7 5 0 0 5 5 5 2 Kelch motif DUF3439 PF11921.8 RUS89606.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GLTT PF01744.20 RUS89607.1 - 0.013 15.3 0.1 9.2 6.1 0.0 4.3 2 1 1 5 5 5 0 GLTT repeat (6 copies) Usp PF00582.26 RUS89608.1 - 6.6e-23 81.8 0.0 9.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family LAT PF15234.6 RUS89609.1 - 0.0016 18.2 29.9 2 8.1 1.5 5.6 1 1 1 2 2 2 1 Linker for activation of T-cells Drf_FH1 PF06346.12 RUS89609.1 - 0.3 10.8 9.8 0.56 9.9 9.8 1.5 1 1 0 1 1 1 0 Formin Homology Region 1 GYD PF08734.11 RUS89610.1 - 0.0022 17.9 11.0 4.4 7.3 0.4 5.2 1 1 6 7 7 7 2 GYD domain Lactococcin_972 PF09683.10 RUS89610.1 - 0.0062 17.1 24.2 0.83 10.2 1.3 6.9 1 1 5 6 6 6 1 Bacteriocin (Lactococcin_972) FANCL_C PF11793.8 RUS89610.1 - 0.02 15.0 17.2 68 3.8 0.1 6.7 1 1 6 7 7 7 0 FANCL C-terminal domain DUF3430 PF11912.8 RUS89610.1 - 0.025 14.6 0.4 0.097 12.7 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) DUF2753 PF10952.8 RUS89610.1 - 0.031 14.4 2.1 15 5.8 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF2753) Peroxin-13_N PF04088.13 RUS89610.1 - 0.43 10.8 18.3 1.6 9.0 0.4 3.6 1 1 1 3 3 3 0 Peroxin 13, N-terminal region FMN_bind PF04205.14 RUS89610.1 - 0.48 11.0 9.8 2.1e+02 2.6 0.0 6.5 8 0 0 8 8 8 0 FMN-binding domain zinc_ribbon_6 PF14599.6 RUS89610.1 - 0.82 9.7 17.7 14 5.7 0.2 4.9 1 1 5 6 6 6 0 Zinc-ribbon Usp PF00582.26 RUS89611.1 - 5.8e-26 91.7 0.2 7.4e-26 91.3 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family Limkain-b1 PF11608.8 RUS89611.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DUF445 PF04286.12 RUS89612.1 - 2e-05 24.6 3.0 0.0002 21.3 3.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF826 PF05696.11 RUS89612.1 - 0.00024 21.1 18.2 3.4 7.8 0.3 7.0 1 1 3 4 4 4 3 Protein of unknown function (DUF826) NAAA-beta PF15508.6 RUS89612.1 - 0.007 16.6 5.4 25 5.3 0.1 4.7 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2497 PF10691.9 RUS89612.1 - 0.16 12.4 23.1 4.7 7.7 3.7 4.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2497) DUF2884 PF11101.8 RUS89612.1 - 0.21 11.1 23.0 1.2 8.5 9.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) COXG PF06240.13 RUS89612.1 - 0.49 10.1 10.1 20 4.9 1.4 3.7 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) BLM10_mid PF16507.5 RUS89612.1 - 0.88 8.1 21.1 1.8e+04 -6.2 21.2 2.9 1 1 0 1 1 1 0 Proteasome-substrate-size regulator, mid region MtrC PF04211.13 RUS89612.1 - 1.5 7.8 32.0 0.47 9.5 10.7 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C Vut_1 PF02592.15 RUS89612.1 - 1.7 8.9 20.6 1.6e+04 -3.9 20.6 3.5 1 1 0 1 1 1 0 Putative vitamin uptake transporter SDA1 PF05285.12 RUS89613.1 - 5.5e-05 22.7 18.4 5.8e-05 22.7 18.4 1.1 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 RUS89613.1 - 0.024 13.4 1.9 0.024 13.5 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 RUS89613.1 - 0.036 12.5 18.4 0.043 12.3 18.4 1.0 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 RUS89613.1 - 0.047 13.1 18.6 0.062 12.7 18.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IFT57 PF10498.9 RUS89613.1 - 0.2 10.6 6.1 0.24 10.3 6.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.12 RUS89613.1 - 0.31 9.2 32.5 0.38 8.9 32.5 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 RUS89613.1 - 1.7 7.1 29.6 2.2 6.7 29.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 RUS89613.1 - 1.9 7.7 12.3 2.6 7.2 12.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 RUS89613.1 - 4.8 5.3 28.0 6.8 4.9 28.0 1.1 1 0 0 1 1 1 0 CDC45-like protein VWA PF00092.28 RUS89614.1 - 1.2e-19 71.3 0.1 1.7e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS89614.1 - 2e-17 63.6 0.0 3.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS89614.1 - 1.2e-13 51.6 0.1 3.5e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RUS89614.1 - 5.4e-07 29.2 0.0 9.9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 RUS89614.1 - 1.1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Astro_capsid_p2 PF16580.5 RUS89614.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike Peptidase_S49_N PF08496.10 RUS89614.1 - 0.075 13.1 0.2 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CobT_C PF11775.8 RUS89614.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain VIT PF08487.10 RUS89614.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain TFIIA PF03153.13 RUS89615.1 - 0.37 10.7 16.6 0.51 10.3 16.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 RUS89615.1 - 0.96 7.6 17.2 1.1 7.5 17.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLU-1 PF08429.11 RUS89616.1 - 8.5e-90 301.3 19.5 1.4e-88 297.3 10.4 3.1 3 0 0 3 3 3 2 PLU-1-like protein JmjC PF02373.22 RUS89616.1 - 2.3e-43 147.2 0.4 5.7e-43 146.0 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 RUS89616.1 - 2.5e-24 84.9 45.9 1.6e-12 47.1 6.2 4.1 4 0 0 4 4 3 3 PHD-finger zf-C5HC2 PF02928.16 RUS89616.1 - 1.3e-17 63.9 11.9 1.3e-17 63.9 11.9 3.0 3 0 0 3 3 2 1 C5HC2 zinc finger ARID PF01388.21 RUS89616.1 - 1.9e-17 63.7 0.0 6e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 RUS89616.1 - 6.5e-14 51.6 0.3 1.4e-13 50.5 0.3 1.6 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 RUS89616.1 - 0.0046 16.5 14.7 0.15 11.6 3.3 3.9 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H_2 PF13832.6 RUS89616.1 - 0.0047 17.1 1.4 0.0047 17.1 1.4 4.8 5 0 0 5 5 4 2 PHD-zinc-finger like domain Med9 PF07544.13 RUS89616.1 - 0.13 12.4 0.8 18 5.5 0.0 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-HC5HC2H PF13771.6 RUS89616.1 - 0.2 11.9 28.7 0.023 14.9 3.6 4.8 4 0 0 4 4 4 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 RUS89616.1 - 8.6 5.9 14.5 0.71 9.5 1.3 3.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Atg14 PF10186.9 RUS89617.1 - 0.0016 17.6 3.5 0.0016 17.6 3.5 3.1 3 0 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 RUS89617.1 - 0.055 13.8 0.1 0.055 13.8 0.1 5.7 5 2 1 6 6 6 0 Coiled-coil domain-containing protein 167 BING4CT PF08149.11 RUS89617.1 - 0.35 10.7 3.2 0.3 10.9 1.0 2.0 2 0 0 2 2 2 0 BING4CT (NUC141) domain WD40_alt PF14077.6 RUS89617.1 - 0.59 10.0 5.1 15 5.5 0.0 3.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif PPP4R2 PF09184.11 RUS89618.1 - 0.0083 15.8 10.5 0.0097 15.5 10.5 1.2 1 0 0 1 1 1 1 PPP4R2 Nop14 PF04147.12 RUS89618.1 - 0.01 14.1 19.3 0.011 13.9 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS89618.1 - 0.015 14.7 12.1 0.017 14.5 12.1 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 RUS89618.1 - 0.061 13.3 25.0 0.074 13.0 25.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 RUS89618.1 - 0.34 9.0 38.6 0.43 8.6 38.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 RUS89618.1 - 7.3 6.4 9.0 8.4 6.2 9.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Glyco_hydro_38C PF07748.13 RUS89619.1 - 0.13 12.4 0.0 5.9 6.9 0.0 2.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Trypsin PF00089.26 RUS89620.1 - 1e-37 130.1 0.5 2.7e-33 115.7 0.3 2.1 1 1 0 2 2 2 2 Trypsin DUF1986 PF09342.11 RUS89620.1 - 1.4e-05 25.4 0.0 3.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) 7tm_1 PF00001.21 RUS89621.1 - 3.6e-12 46.2 15.1 5.6e-12 45.5 15.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS89621.1 - 4.4e-12 45.9 14.4 6.6e-12 45.3 14.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw RhoGEF PF00621.20 RUS89622.1 - 1.1e-17 64.9 0.0 2e-17 64.0 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 RUS89622.1 - 2.8e-07 30.7 0.0 1.9e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PWI PF01480.17 RUS89622.1 - 0.0024 18.2 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 PWI domain PH PF00169.29 RUS89622.1 - 0.0033 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 PH domain DDE_3 PF13358.6 RUS89622.1 - 0.077 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Abhydrolase_1 PF00561.20 RUS89625.1 - 1.5e-18 67.4 0.1 9.6e-16 58.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS89625.1 - 4.9e-15 56.7 1.0 6.5e-15 56.3 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 RUS89625.1 - 1.2e-06 27.8 0.0 3.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 RUS89625.1 - 2.5e-05 23.7 0.0 6.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 RUS89625.1 - 0.056 13.0 0.0 0.88 9.1 0.1 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Paramecium_SA PF01508.16 RUS89626.1 - 2.7e-05 24.5 20.6 5.5e+02 1.1 20.6 3.3 1 1 0 1 1 1 0 Paramecium surface antigen domain Vanabin-2 PF11437.8 RUS89626.1 - 0.0031 17.6 31.6 1.7 8.8 14.2 3.5 1 1 1 2 2 2 2 Vanadium-binding protein 2 BIR PF00653.21 RUS89627.1 - 9.5e-33 112.7 4.4 2.9e-21 75.9 1.5 3.2 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS89627.1 - 6.6e-13 48.3 11.6 6.6e-13 48.3 11.6 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS89627.1 - 3.1e-05 23.7 11.5 9.2e-05 22.2 11.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS89627.1 - 0.0079 16.1 11.5 0.03 14.3 11.5 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RUS89627.1 - 0.012 16.0 12.4 0.012 16.0 12.4 2.4 3 0 0 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 RUS89627.1 - 0.12 12.4 7.4 0.85 9.7 7.4 2.4 1 1 0 1 1 1 0 RING-type zinc-finger UPF0114 PF03350.16 RUS89628.1 - 0.014 15.6 41.8 1.4 9.1 2.1 5.4 1 1 3 4 4 4 0 Uncharacterized protein family, UPF0114 NDUFA12 PF05071.16 RUS89629.1 - 4.3e-24 85.2 0.6 5.1e-24 84.9 0.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf_C2H2_10 PF18414.1 RUS89630.1 - 5.6e-06 25.8 3.6 5.6e-06 25.8 3.6 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger CC2-LZ PF16516.5 RUS89630.1 - 3.2e-05 24.2 16.7 3.2e-05 24.2 16.7 8.3 3 2 4 7 7 7 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PEP-utilisers_N PF05524.13 RUS89630.1 - 0.0008 19.6 5.3 0.0008 19.6 5.3 5.2 4 2 0 4 4 4 1 PEP-utilising enzyme, N-terminal NEMO PF11577.8 RUS89630.1 - 0.00086 19.3 5.7 0.00086 19.3 5.7 6.4 4 2 1 6 6 6 1 NF-kappa-B essential modulator NEMO DUF1664 PF07889.12 RUS89630.1 - 0.014 15.4 1.4 0.014 15.4 1.4 6.7 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 RUS89630.1 - 0.017 15.0 0.6 0.017 15.0 0.6 7.3 7 2 1 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CbeA_antitoxin PF06154.11 RUS89630.1 - 0.88 10.2 3.8 0.58 10.8 0.2 2.4 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Galactosyl_T PF01762.21 RUS89631.1 - 2.2e-28 99.4 0.0 2.8e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 RUS89631.1 - 4e-05 23.2 0.1 4.9e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Fringe-like Adaptin_N PF01602.20 RUS89633.1 - 0.0026 16.4 0.1 0.0035 16.0 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region STAT_alpha PF01017.20 RUS89633.1 - 0.031 14.2 0.6 0.052 13.4 0.6 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain ApoLp-III PF07464.11 RUS89633.1 - 0.07 13.2 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PolyA_pol_RNAbd PF12627.7 RUS89633.1 - 0.09 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A PMC2NT PF08066.12 RUS89633.1 - 0.11 13.3 2.9 0.16 12.7 2.1 1.7 1 1 1 2 2 2 0 PMC2NT (NUC016) domain V-ATPase_G PF03179.15 RUS89633.1 - 0.11 13.0 0.4 0.2 12.2 0.4 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF948 PF06103.11 RUS89633.1 - 0.13 12.5 0.1 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-I PF07778.11 RUS89633.1 - 0.16 10.7 1.0 0.2 10.3 1.0 1.1 1 0 0 1 1 1 0 Mis6 SpoIIIAH PF12685.7 RUS89633.1 - 0.17 11.7 2.4 9.3 6.0 1.9 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF2981 PF11200.8 RUS89633.1 - 0.69 9.6 3.1 1.4 8.6 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) FliT PF05400.13 RUS89633.1 - 1 10.2 4.1 16 6.4 3.8 2.4 1 1 0 1 1 1 0 Flagellar protein FliT DUF1664 PF07889.12 RUS89633.1 - 5.3 7.1 6.2 1.2 9.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CRF PF00473.17 RUS89634.1 - 0.00015 21.8 33.1 1.7 8.8 0.3 7.9 1 1 7 8 8 8 7 Corticotropin-releasing factor family MITF_TFEB_C_3_N PF15951.5 RUS89634.1 - 0.0022 18.7 16.9 1.8e+04 -3.8 17.2 4.1 1 1 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Glycoprotein_B PF00606.18 RUS89634.1 - 0.26 10.7 2.0 5.8 6.3 0.3 2.1 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B ectodomain NADH_Oxid_Nqo15 PF11497.8 RUS89634.1 - 0.98 9.5 10.0 4.7 7.3 2.7 2.5 1 1 1 2 2 2 0 NADH-quinone oxidoreductase chain 15 UQ_con PF00179.26 RUS89635.1 - 5.4e-47 159.0 0.0 6.3e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS89635.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RUS89635.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 RUS89635.1 - 0.037 14.3 0.1 0.043 14.1 0.1 1.3 1 1 0 1 1 1 0 RWD domain Carn_acyltransf PF00755.20 RUS89636.1 - 1.6e-157 525.7 0.0 1.2e-138 463.4 0.1 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF4202 PF13875.6 RUS89636.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) zf-H2C2_2 PF13465.6 RUS89638.1 - 1.7e-27 94.6 67.5 6.9e-08 32.6 3.6 9.2 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS89638.1 - 8.5e-27 92.1 76.7 2e-05 24.8 3.7 9.8 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89638.1 - 1.4e-17 62.9 80.0 0.0014 19.3 1.0 10.1 10 0 0 10 10 9 8 C2H2-type zinc finger Homeodomain PF00046.29 RUS89638.1 - 7.4e-09 35.3 0.1 2.4e-08 33.7 0.1 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_jaz PF12171.8 RUS89638.1 - 2.1e-06 27.8 49.8 0.018 15.3 0.9 8.0 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS89638.1 - 0.00062 19.7 1.8 0.00062 19.7 1.8 8.4 8 0 0 8 8 8 3 C2H2-type zinc finger zf-met PF12874.7 RUS89638.1 - 0.00078 19.7 2.8 0.00078 19.7 2.8 8.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 RUS89638.1 - 0.02 15.0 0.4 0.02 15.0 0.4 5.7 5 1 2 7 7 7 0 Zinc-finger zf_UBZ PF18439.1 RUS89638.1 - 0.091 12.4 43.3 0.4 10.3 0.3 8.0 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger BHD_1 PF10403.9 RUS89638.1 - 0.14 12.0 0.2 0.49 10.3 0.0 2.0 2 0 0 2 2 1 0 Rad4 beta-hairpin domain 1 zf-C2H2_2 PF12756.7 RUS89638.1 - 0.44 10.9 48.0 1.9 8.8 0.6 8.2 3 2 4 7 7 6 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS89638.1 - 0.85 9.8 33.4 0.73 10.0 3.0 6.5 5 2 1 6 6 6 0 Zinc ribbon domain zf-Di19 PF05605.12 RUS89638.1 - 1.2 9.5 42.5 0.018 15.3 3.7 5.7 4 2 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.6 RUS89638.1 - 2.8 8.0 29.3 1.9 8.6 1.0 6.8 3 2 3 6 6 6 0 CpXC protein DUF2315 PF10231.9 RUS89641.1 - 7.8e-43 145.5 1.8 9.9e-43 145.1 1.8 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 Kelch_4 PF13418.6 RUS89642.1 - 8.1e-22 77.0 18.5 3.4e-08 33.4 0.0 6.7 4 4 3 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS89642.1 - 1.8e-19 69.3 1.9 4.8e-05 23.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 RUS89642.1 - 2.7e-18 65.8 13.4 3.1e-06 27.3 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS89642.1 - 7.6e-17 60.9 16.8 0.0023 18.1 0.0 7.1 8 1 0 8 8 8 4 Kelch motif Kelch_1 PF01344.25 RUS89642.1 - 6.1e-14 51.3 15.4 0.0002 20.9 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 RUS89642.1 - 4.2e-12 45.5 14.2 0.0062 16.5 2.4 6.9 5 2 0 5 5 5 4 Kelch motif RAG2 PF03089.14 RUS89642.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Recombination activating protein 2 Fibrinogen_C PF00147.18 RUS89643.1 - 4.3e-49 167.3 3.1 6.4e-49 166.7 3.1 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CLZ PF16526.5 RUS89643.1 - 0.65 10.4 7.1 1.8 9.0 2.6 3.3 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lectin_N PF03954.14 RUS89643.1 - 4.5 7.0 8.1 0.26 11.0 0.3 2.8 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain EGF PF00008.27 RUS89644.1 - 1.4e-81 268.3 264.1 1.4e-09 38.1 5.9 19.8 19 1 0 19 19 19 15 EGF-like domain hEGF PF12661.7 RUS89644.1 - 2.4e-50 167.5 211.7 5e-08 33.3 6.3 19.5 18 0 0 18 18 18 14 Human growth factor-like EGF MNNL PF07657.13 RUS89644.1 - 5.3e-24 84.1 1.9 5.3e-24 84.1 1.9 5.3 4 1 0 4 4 4 1 N terminus of Notch ligand DSL PF01414.19 RUS89644.1 - 1.7e-23 82.7 7.5 1.7e-23 82.7 7.5 13.8 10 3 5 15 15 15 1 Delta serrate ligand EGF_CA PF07645.15 RUS89644.1 - 1.7e-21 76.1 259.4 3.1e-05 24.1 4.8 18.6 10 6 7 17 17 17 13 Calcium-binding EGF domain EGF_2 PF07974.13 RUS89644.1 - 2.5e-17 62.9 308.9 0.0009 19.6 10.0 20.2 20 1 0 20 20 20 12 EGF-like domain EGF_3 PF12947.7 RUS89644.1 - 0.015 15.5 4.6 0.015 15.5 4.6 18.3 15 5 3 18 18 18 0 EGF domain ACP PF06857.11 RUS89644.1 - 0.019 15.2 0.2 0.046 14.0 0.2 1.6 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) TMEM132D_C PF15706.5 RUS89644.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FXa_inhibition PF14670.6 RUS89644.1 - 0.52 10.6 210.7 0.2 12.0 2.9 17.9 8 5 10 18 18 18 0 Coagulation Factor Xa inhibitory site Rpp20 PF12328.8 RUS89645.1 - 4.9e-18 65.4 0.1 4.2e-12 46.2 0.0 2.4 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 RUS89645.1 - 5.7e-12 45.3 0.1 7.6e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Alba TTKRSYEDQ PF10212.9 RUS89646.1 - 1.2e-186 621.8 20.8 1.2e-186 621.8 20.8 2.1 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 RUS89646.1 - 6.2e-29 100.2 13.4 6.2e-29 100.2 13.4 5.0 4 2 0 4 4 4 1 Predicted coiled-coil domain-containing protein HMMR_N PF15905.5 RUS89646.1 - 0.0073 15.8 15.0 0.0073 15.8 15.0 4.7 5 1 0 5 5 5 2 Hyaluronan mediated motility receptor N-terminal DUF501 PF04417.12 RUS89646.1 - 2.1 8.1 5.7 42 3.9 0.0 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF501) TMCO5 PF14992.6 RUS89646.1 - 2.7 7.5 47.5 0.036 13.6 15.8 4.4 3 1 1 4 4 4 0 TMCO5 family APG6_N PF17675.1 RUS89646.1 - 5.3 7.6 0.0 5.3 7.6 0.0 6.5 4 3 2 6 6 6 0 Apg6 coiled-coil region Spy1 PF11357.8 RUS89647.1 - 1.8e-54 183.6 6.1 2.7e-54 183.0 6.1 1.3 1 0 0 1 1 1 1 Cell cycle regulatory protein BACK PF07707.15 RUS89648.1 - 9.1e-14 51.4 1.8 1.5e-13 50.7 0.8 1.9 2 1 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS89648.1 - 5.2e-10 39.6 0.2 3.6e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain RTTN_N PF14726.6 RUS89648.1 - 0.15 12.8 0.1 0.45 11.4 0.1 1.9 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DUF2709 PF10915.8 RUS89649.1 - 0.0036 16.6 0.5 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2709) DUF4455 PF14643.6 RUS89649.1 - 0.0096 14.6 0.6 0.0096 14.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) Sugarporin_N PF11471.8 RUS89649.1 - 0.018 15.0 0.1 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension PP1_bind PF15276.6 RUS89649.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 1 binding MerR-DNA-bind PF09278.11 RUS89649.1 - 0.83 10.2 4.6 14 6.3 0.0 3.8 4 1 0 4 4 4 0 MerR, DNA binding DHFR_1 PF00186.19 RUS89650.1 - 2.8e-37 127.9 0.0 3.4e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase ADH_zinc_N PF00107.26 RUS89651.1 - 4.5e-23 81.7 0.0 8.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS89651.1 - 9.6e-11 42.9 0.0 3.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS89651.1 - 0.00047 20.0 0.0 0.049 13.5 0.0 2.9 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS89651.1 - 0.0048 16.8 0.1 0.014 15.3 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 RUS89651.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain MOSC PF03473.17 RUS89652.1 - 1.7e-31 108.9 0.0 3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 RUS89652.1 - 7e-28 96.9 0.0 1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain CTV_P6 PF06706.11 RUS89653.1 - 0.00089 18.9 1.1 0.0016 18.1 1.1 1.3 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein Cadherin_C_2 PF16492.5 RUS89653.1 - 0.04 14.7 0.0 0.04 14.7 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF5137 PF17220.3 RUS89653.1 - 0.13 13.2 0.6 0.36 11.7 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF5137) CUB PF00431.20 RUS89654.1 - 2.5e-12 47.1 0.0 5e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 CUB domain Cystatin PF00031.21 RUS89655.1 - 5.8e-20 71.4 0.0 2.5e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 RUS89655.1 - 1.2e-08 35.1 0.3 5.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Peptidase_C1 PF00112.23 RUS89656.1 - 1.5e-74 250.7 4.9 2.9e-74 249.8 4.9 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Cystatin PF00031.21 RUS89656.1 - 2.2e-13 50.2 0.7 8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Cystatin domain Inhibitor_I29 PF08246.12 RUS89656.1 - 1.1e-08 35.4 1.0 2.2e-08 34.4 1.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) SQAPI PF16845.5 RUS89656.1 - 8.7e-07 29.2 0.2 0.0097 16.2 0.1 2.6 2 0 0 2 2 2 2 Aspartic acid proteinase inhibitor Peptidase_C1_2 PF03051.15 RUS89656.1 - 1.2e-05 24.3 0.8 0.0016 17.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family UAA PF08449.11 RUS89657.1 - 3.3e-67 226.9 25.7 4e-67 226.6 25.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RUS89657.1 - 0.00069 19.8 34.5 0.023 14.9 17.0 3.4 3 2 1 4 4 4 2 EamA-like transporter family Rad51 PF08423.11 RUS89658.1 - 1.8e-116 387.9 0.0 2.4e-116 387.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 RUS89658.1 - 1.4e-09 37.8 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 RUS89658.1 - 6.1e-07 29.2 0.1 9.8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 RUS89658.1 - 2.6e-06 27.9 0.2 9.2e-06 26.2 0.3 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_28 PF13521.6 RUS89658.1 - 0.0055 17.0 0.2 0.026 14.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 RUS89658.1 - 0.011 15.1 1.0 0.12 11.7 1.0 2.3 1 1 0 1 1 1 0 KaiC AAA_22 PF13401.6 RUS89658.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RUS89658.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 RUS89658.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain DnaB_C PF03796.15 RUS89658.1 - 0.1 11.9 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HHH PF00633.23 RUS89658.1 - 0.1 12.5 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif LRR_6 PF13516.6 RUS89659.1 - 3.3e-06 26.7 19.6 0.00096 19.0 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 RUS89659.1 - 0.16 12.6 5.8 69 4.6 2.8 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat YlaC PF10777.9 RUS89659.1 - 0.32 10.8 1.9 0.3 10.9 0.2 1.7 1 1 1 2 2 2 0 Inner membrane protein YlaC Sushi PF00084.20 RUS89660.1 - 2.9e-08 34.2 0.2 6e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Adeno_E3_CR2 PF02439.15 RUS89660.1 - 4.6e-05 23.1 1.8 7.4e-05 22.4 1.8 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RUS89660.1 - 0.00097 19.1 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family MAP17 PF15807.5 RUS89660.1 - 0.002 18.3 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 RUS89660.1 - 0.008 17.0 0.0 0.011 16.6 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 RUS89660.1 - 0.0089 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5385) Shisa PF13908.6 RUS89660.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 RUS89660.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) FAM163 PF15069.6 RUS89660.1 - 0.017 15.6 0.6 0.049 14.1 0.3 1.6 1 1 1 2 2 2 0 FAM163 family RCR PF12273.8 RUS89660.1 - 0.031 14.9 0.1 0.046 14.4 0.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 RUS89660.1 - 0.038 14.3 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A Cadherin_C_2 PF16492.5 RUS89660.1 - 0.048 14.4 0.0 0.096 13.4 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PrgI PF12666.7 RUS89660.1 - 0.061 14.0 0.0 0.093 13.4 0.0 1.2 1 0 0 1 1 1 0 PrgI family protein Stevor PF17410.2 RUS89660.1 - 0.079 12.5 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Sigma_reg_N PF13800.6 RUS89660.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TIR_2 PF13676.6 RUS89661.1 - 0.0093 16.6 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 RUS89662.1 - 7.4e-90 295.2 0.7 3.8e-14 52.5 0.0 10.1 9 2 0 9 9 9 8 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS89662.1 - 7.7e-89 292.4 30.8 1.2e-15 57.8 0.2 10.0 10 1 0 10 10 9 9 Immunoglobulin domain ig PF00047.25 RUS89662.1 - 1.2e-61 204.9 17.3 2.9e-10 40.2 0.1 9.8 9 1 0 9 9 9 8 Immunoglobulin domain Ig_2 PF13895.6 RUS89662.1 - 4.4e-54 180.7 25.5 7.2e-10 39.1 0.1 10.9 9 2 0 9 9 9 7 Immunoglobulin domain V-set PF07686.17 RUS89662.1 - 7.1e-41 138.8 14.2 2.9e-09 37.1 0.1 10.3 8 2 1 9 9 9 7 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS89662.1 - 1.8e-16 59.5 0.2 0.017 14.7 0.0 7.7 8 0 0 8 8 8 4 Immunoglobulin domain C2-set_2 PF08205.12 RUS89662.1 - 2.5e-12 46.7 10.9 0.00068 19.7 0.0 7.7 8 0 0 8 8 8 3 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RUS89662.1 - 8.7e-08 32.3 0.4 17 5.8 0.0 7.7 10 1 0 10 10 9 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS89662.1 - 9.1e-08 32.1 0.1 4 7.6 0.0 7.1 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 RUS89662.1 - 2.1e-07 30.7 2.8 0.73 9.7 0.0 6.1 6 1 0 6 6 6 2 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 RUS89662.1 - 3.1e-07 30.3 7.1 0.63 10.1 0.0 6.9 8 0 0 8 8 7 2 C17orf99 Ig domain Herpes_gE PF02480.16 RUS89662.1 - 9.9e-06 24.6 0.6 2 7.1 0.0 5.0 5 2 0 5 5 5 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 RUS89662.1 - 1.3e-05 25.3 0.4 0.028 14.6 0.0 4.3 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 C1-set PF07654.15 RUS89662.1 - 8.4e-05 22.9 0.8 2 8.9 0.0 5.3 5 0 0 5 5 5 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 RUS89662.1 - 0.0085 16.1 1.9 12 5.9 0.0 5.2 6 0 0 6 6 6 0 CD47 immunoglobulin-like domain Invasin_D3 PF09134.10 RUS89662.1 - 0.023 15.0 5.5 0.15 12.4 0.1 4.1 4 0 0 4 4 3 0 Invasin, domain 3 V-set_2 PF15910.5 RUS89662.1 - 0.04 14.0 0.1 0.57 10.3 0.0 3.0 3 0 0 3 3 3 0 ICOS V-set domain Atrophin-1 PF03154.15 RUS89662.1 - 5.9 5.0 5.5 12 4.0 5.5 1.5 1 0 0 1 1 1 0 Atrophin-1 family Ig_3 PF13927.6 RUS89663.1 - 3.8e-08 33.8 0.1 5.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS89663.1 - 6.6e-07 29.4 0.1 8.6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS89663.1 - 1.6e-06 28.0 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS89663.1 - 6.8e-06 26.3 0.1 8.4e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Glycolytic PF00274.19 RUS89664.1 - 1e-174 580.2 0.0 1.2e-174 580.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I p450 PF00067.22 RUS89665.1 - 1.5e-72 244.9 0.0 1.7e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCM6_C PF18263.1 RUS89665.1 - 0.026 14.8 0.5 0.058 13.6 0.5 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain FeoB_C PF07664.12 RUS89665.1 - 0.062 13.0 1.9 4.7 7.0 0.3 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus p450 PF00067.22 RUS89666.1 - 6.7e-10 38.3 0.0 7.7e-10 38.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeoB_C PF07664.12 RUS89666.1 - 0.17 11.6 5.8 0.81 9.4 0.2 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B C terminus RNase_PH PF01138.21 RUS89668.1 - 7.5e-36 123.6 0.0 8.1e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS89668.1 - 1.4e-15 57.0 0.1 7.7e-12 45.1 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 RUS89668.1 - 8e-10 39.1 1.6 1.3e-09 38.4 0.0 2.2 3 0 0 3 3 3 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 RUS89668.1 - 2e-06 27.6 0.0 5.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 KH domain S1 PF00575.23 RUS89668.1 - 1.7e-05 25.1 0.0 0.0001 22.5 0.0 2.5 3 0 0 3 3 3 1 S1 RNA binding domain Actin PF00022.19 RUS89670.1 - 4.4e-54 183.7 0.0 3.6e-52 177.4 0.0 2.1 1 1 0 1 1 1 1 Actin DUF3692 PF12469.8 RUS89670.1 - 0.027 14.7 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein MreB_Mbl PF06723.13 RUS89670.1 - 0.47 9.2 1.8 8.4 5.1 0.0 2.4 3 0 0 3 3 3 0 MreB/Mbl protein EF-hand_1 PF00036.32 RUS89671.1 - 6.3e-17 59.8 1.0 2.6e-07 29.7 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 RUS89671.1 - 1.2e-16 60.9 0.1 2e-14 53.8 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS89671.1 - 2.7e-15 55.9 0.6 4.7e-13 48.8 0.3 3.3 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS89671.1 - 8.6e-14 50.2 0.0 3.2e-07 29.7 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 RUS89671.1 - 1.2e-08 34.0 4.6 0.0011 18.3 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RUS89671.1 - 6.4e-08 32.8 0.0 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RUS89671.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RUS89671.1 - 0.0093 16.3 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RUS89671.1 - 0.017 15.1 0.0 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RUS89671.1 - 0.037 14.9 0.0 0.073 13.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain DUF5580 PF17743.1 RUS89671.1 - 0.072 11.6 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) preATP-grasp_3 PF18301.1 RUS89671.1 - 0.093 13.0 0.2 1.2 9.4 0.0 2.4 3 0 0 3 3 3 0 pre ATP-grasp 3 domain Speriolin_C PF15059.6 RUS89671.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus TBPIP PF07106.13 RUS89672.1 - 2.2e-26 91.6 0.5 4.7e-26 90.5 0.5 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 RUS89672.1 - 4e-13 49.3 0.5 8.2e-13 48.2 0.2 1.8 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF4763 PF15960.5 RUS89672.1 - 0.00025 20.5 1.6 0.24 10.7 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4763) TrmB PF01978.19 RUS89672.1 - 0.0053 16.6 0.9 0.078 12.9 0.1 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF4363 PF14276.6 RUS89672.1 - 0.0059 16.7 2.9 1.4 9.1 0.5 3.5 1 1 3 4 4 4 1 Domain of unknown function (DUF4363) Laminin_II PF06009.12 RUS89672.1 - 0.0091 16.0 0.6 0.015 15.3 0.6 1.3 1 0 0 1 1 1 1 Laminin Domain II Penicillinase_R PF03965.16 RUS89672.1 - 0.022 15.1 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 Penicillinase repressor Spc7 PF08317.11 RUS89672.1 - 0.04 12.8 2.5 0.054 12.4 2.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2492 PF10678.9 RUS89672.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF4477 PF14780.6 RUS89672.1 - 0.052 13.2 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) BRE1 PF08647.11 RUS89672.1 - 0.53 10.4 4.0 6.8 6.8 0.2 3.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Translin PF01997.16 RUS89673.1 - 6.6e-55 186.3 0.0 8.7e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Translin family SH2 PF00017.24 RUS89674.1 - 1.7e-10 40.9 0.0 4.6e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 RUS89674.1 - 1.3e-07 31.8 0.5 3.3e-07 30.6 0.5 1.7 1 0 0 1 1 1 1 SOCS box Met_synt_B12 PF02965.17 RUS89675.1 - 4.9e-110 367.3 0.9 7.8e-110 366.6 0.9 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 RUS89675.1 - 2.7e-78 263.5 0.0 5.3e-78 262.5 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 RUS89675.1 - 1.5e-55 188.5 0.1 4.4e-55 187.0 0.1 1.9 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 RUS89675.1 - 4.3e-24 84.7 0.0 1.7e-23 82.9 0.0 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 RUS89675.1 - 1.6e-20 73.4 0.4 8.3e-18 64.6 0.3 3.8 3 0 0 3 3 3 1 B12 binding domain Cgr1 PF03879.14 RUS89675.1 - 2.4 8.6 4.3 2.5 8.5 1.8 2.1 2 0 0 2 2 2 0 Cgr1 family SNARE PF05739.19 RUS89676.1 - 9.2e-15 54.4 0.3 9.2e-15 54.4 0.3 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 RUS89676.1 - 5.2e-08 31.9 0.8 1.8e-07 30.2 0.2 2.4 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 RUS89676.1 - 3.2e-05 23.7 20.1 0.0031 17.2 0.8 3.3 2 1 1 3 3 3 3 Syntaxin DUF16 PF01519.16 RUS89676.1 - 0.045 14.3 14.6 0.072 13.6 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Spectrin PF00435.21 RUS89676.1 - 0.088 13.3 9.7 1.7 9.2 0.2 3.3 2 1 0 2 2 2 0 Spectrin repeat Dynamin_M PF01031.20 RUS89676.1 - 0.1 11.8 10.2 0.041 13.1 2.9 2.6 3 0 0 3 3 3 0 Dynamin central region BLOC1_2 PF10046.9 RUS89676.1 - 0.11 12.8 0.5 0.11 12.8 0.5 3.1 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 RUS89676.1 - 0.11 12.5 10.7 0.49 10.4 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MerR-DNA-bind PF09278.11 RUS89676.1 - 0.29 11.7 3.1 1 10.0 0.4 2.9 3 0 0 3 3 3 0 MerR, DNA binding Apolipoprotein PF01442.18 RUS89676.1 - 3.6 7.4 12.9 5.1 6.9 7.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Allexi_40kDa PF05549.11 RUS89676.1 - 7.2 6.0 13.8 14 5.1 6.8 2.7 2 1 1 3 3 3 0 Allexivirus 40kDa protein DUF948 PF06103.11 RUS89676.1 - 9.9 6.5 7.2 4.2 7.7 0.3 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-H2C2_2 PF13465.6 RUS89678.1 - 1.5e-29 101.1 109.6 4.9e-06 26.7 0.8 13.0 14 0 0 14 14 14 9 Zinc-finger double domain zf-C2H2 PF00096.26 RUS89678.1 - 6.7e-24 83.0 104.0 0.00035 20.9 1.8 12.1 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89678.1 - 2.7e-23 80.6 99.5 0.012 16.3 0.5 12.1 12 0 0 12 12 12 11 C2H2-type zinc finger zf-met PF12874.7 RUS89678.1 - 0.0001 22.6 73.8 0.072 13.5 0.5 11.5 11 0 0 11 11 11 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS89678.1 - 0.0005 20.3 71.1 0.21 11.9 1.4 10.9 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding ISPD_C PF18706.1 RUS89678.1 - 0.057 13.1 0.8 0.34 10.5 0.3 2.3 2 0 0 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain zf-C2H2_6 PF13912.6 RUS89678.1 - 0.72 9.9 0.1 0.72 9.9 0.1 10.2 12 0 0 12 12 12 0 C2H2-type zinc finger FYDLN_acid PF09538.10 RUS89678.1 - 1 10.0 9.1 16 6.2 0.6 4.3 3 1 1 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF4611 PF15387.6 RUS89679.1 - 0.007 16.6 8.7 0.007 16.6 8.7 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4611) SelP_N PF04592.14 RUS89679.1 - 0.34 10.3 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Rubella_Capsid PF05750.11 RUS89679.1 - 0.45 10.1 7.1 0.87 9.1 7.1 1.5 1 0 0 1 1 1 0 Rubella capsid protein NOA36 PF06524.12 RUS89679.1 - 0.77 9.0 10.0 1.5 8.1 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 RUS89679.1 - 2.6 7.6 7.7 5.1 6.6 7.7 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 RUS89679.1 - 4.4 7.8 16.7 9 6.8 16.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rhabdo_ncap PF00945.18 RUS89679.1 - 6 5.6 6.8 9.5 5.0 6.8 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CDC45 PF02724.14 RUS89681.1 - 4.5e-05 22.0 18.4 5.2e-05 21.8 18.4 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2052 PF09747.9 RUS89681.1 - 0.00011 22.5 15.8 0.00013 22.2 15.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CCSAP PF15748.5 RUS89681.1 - 0.00032 21.0 21.0 0.00039 20.7 21.0 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated RNA_pol_Rpc4 PF05132.14 RUS89681.1 - 0.00056 20.4 16.8 0.00076 19.9 16.8 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 DDHD PF02862.17 RUS89681.1 - 0.00076 19.7 3.9 0.00089 19.5 3.9 1.2 1 0 0 1 1 1 1 DDHD domain YL1 PF05764.13 RUS89681.1 - 0.00087 19.5 40.5 0.0011 19.1 40.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SRP-alpha_N PF04086.13 RUS89681.1 - 0.0023 17.9 26.7 0.0034 17.3 26.7 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal PTPRCAP PF15713.5 RUS89681.1 - 0.0032 17.8 12.8 0.0043 17.3 12.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated DUF4603 PF15376.6 RUS89681.1 - 0.0062 14.0 21.4 0.0072 13.8 21.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) SET PF00856.28 RUS89681.1 - 0.0081 16.6 1.1 0.01 16.2 1.1 1.3 1 0 0 1 1 1 1 SET domain RR_TM4-6 PF06459.12 RUS89681.1 - 0.011 15.6 28.4 0.014 15.3 28.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 RUS89681.1 - 0.011 16.0 30.6 0.015 15.6 30.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_11 PF13086.6 RUS89681.1 - 0.017 14.9 14.1 0.018 14.8 14.1 1.2 1 0 0 1 1 1 0 AAA domain Dsh_C PF12316.8 RUS89681.1 - 0.019 15.4 7.0 0.029 14.8 7.0 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF5308 PF17233.2 RUS89681.1 - 0.023 14.9 2.1 0.031 14.5 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Tim54 PF11711.8 RUS89681.1 - 0.031 13.1 23.2 0.041 12.7 23.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRP38_assoc PF12871.7 RUS89681.1 - 0.039 14.6 14.9 0.068 13.8 14.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GPCR_chapero_1 PF11904.8 RUS89681.1 - 0.04 13.4 19.1 0.05 13.0 19.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone TIMELESS_C PF05029.13 RUS89681.1 - 0.049 12.8 21.6 0.056 12.6 21.6 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region DUF4228 PF14009.6 RUS89681.1 - 0.081 13.3 9.9 0.1 12.9 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Vfa1 PF08432.10 RUS89681.1 - 0.084 13.2 36.5 0.11 12.8 36.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mitofilin PF09731.9 RUS89681.1 - 0.11 11.3 22.1 0.13 11.1 22.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MDM1 PF15501.6 RUS89681.1 - 0.14 11.3 28.3 0.18 10.9 28.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Spt5_N PF11942.8 RUS89681.1 - 0.18 12.8 13.0 0.26 12.3 13.0 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal AF-4 PF05110.13 RUS89681.1 - 0.2 9.7 31.7 0.23 9.5 31.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SLC12 PF03522.15 RUS89681.1 - 0.2 10.6 18.4 0.23 10.4 18.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 YqfQ PF14181.6 RUS89681.1 - 0.23 11.7 26.0 0.35 11.1 26.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF5427 PF10310.9 RUS89681.1 - 0.23 10.4 21.3 0.28 10.1 21.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPL5 PF18168.1 RUS89681.1 - 0.24 10.6 17.6 0.3 10.3 17.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Neur_chan_memb PF02932.16 RUS89681.1 - 0.29 11.2 9.8 0.32 11.0 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.9 RUS89681.1 - 0.3 9.9 13.9 0.36 9.6 13.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2126 PF09899.9 RUS89681.1 - 0.34 8.9 7.9 0.4 8.7 7.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CENP-N PF05238.13 RUS89681.1 - 0.35 10.1 15.0 0.45 9.7 15.0 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like SpoIIP PF07454.11 RUS89681.1 - 0.4 10.1 25.5 0.52 9.7 25.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4551 PF15087.6 RUS89681.1 - 0.42 9.4 9.1 0.43 9.3 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF913 PF06025.12 RUS89681.1 - 0.46 9.4 8.5 0.52 9.2 8.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RUS89681.1 - 0.56 8.9 16.5 0.66 8.7 16.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4776 PF16003.5 RUS89681.1 - 0.56 9.1 29.0 0.69 8.8 29.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) eIF-3_zeta PF05091.12 RUS89681.1 - 0.62 9.0 17.5 0.74 8.7 17.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 RUS89681.1 - 0.71 9.8 10.7 1.1 9.1 10.7 1.4 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 RUS89681.1 - 0.8 8.9 11.2 0.93 8.6 11.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 RUS89681.1 - 0.97 9.0 15.6 1.6 8.3 15.6 1.3 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 RUS89681.1 - 1 8.7 16.4 1.4 8.2 16.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LicD PF04991.13 RUS89681.1 - 1.1 9.4 21.0 1.3 9.1 21.0 1.1 1 0 0 1 1 1 0 LicD family GAGA_bind PF06217.12 RUS89681.1 - 1.1 9.5 28.7 1.8 8.8 28.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family VIT1 PF01988.19 RUS89681.1 - 1.3 8.8 3.9 1.9 8.3 3.9 1.2 1 0 0 1 1 1 0 VIT family ICA69 PF04629.14 RUS89681.1 - 1.5 9.1 19.0 1.7 8.9 19.0 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain MDM10 PF12519.8 RUS89681.1 - 1.5 7.6 17.1 1.7 7.4 17.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Membralin PF09746.9 RUS89681.1 - 1.7 7.6 11.5 2 7.4 11.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Nop53 PF07767.11 RUS89681.1 - 1.7 7.9 46.5 2.3 7.5 46.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAPS PF04499.15 RUS89681.1 - 1.9 7.2 12.2 2.2 7.0 12.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4569 PF15133.6 RUS89681.1 - 2 8.1 16.2 2.4 7.8 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4614 PF15391.6 RUS89681.1 - 2.1 8.3 16.1 2.8 7.9 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Paramyxo_ncap PF00973.19 RUS89681.1 - 2.3 7.0 12.5 2.7 6.8 12.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DAG_kinase_N PF14513.6 RUS89681.1 - 2.4 8.4 19.8 3.2 7.9 19.8 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Gti1_Pac2 PF09729.9 RUS89681.1 - 2.7 8.0 20.2 3.7 7.6 20.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Hydin_ADK PF17213.3 RUS89681.1 - 2.9 8.1 10.8 4 7.7 10.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RP-C_C PF11800.8 RUS89681.1 - 2.9 7.9 9.5 3.9 7.5 9.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2151 PF10221.9 RUS89681.1 - 3.2 6.3 18.9 3.7 6.0 18.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Hid1 PF12722.7 RUS89681.1 - 3.3 5.7 14.6 3.6 5.6 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 RUS89681.1 - 4.3 6.0 17.1 5.4 5.7 17.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SelP_N PF04592.14 RUS89681.1 - 4.4 6.6 16.3 5.8 6.2 16.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Paf1 PF03985.13 RUS89681.1 - 4.4 6.2 33.3 6 5.7 33.3 1.1 1 0 0 1 1 1 0 Paf1 MCM_bind PF09739.9 RUS89681.1 - 4.7 5.6 19.1 5.6 5.3 19.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Ctr PF04145.15 RUS89681.1 - 4.7 7.8 6.5 6.9 7.3 6.5 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF262 PF03235.14 RUS89681.1 - 4.8 7.3 11.6 5.8 7.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF3405 PF11885.8 RUS89681.1 - 4.9 5.6 19.5 6.6 5.2 19.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) GREB1 PF15782.5 RUS89681.1 - 5.3 4.0 11.3 6.1 3.8 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 RUS89681.1 - 5.3 5.9 11.0 5.8 5.7 11.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S64 PF08192.11 RUS89681.1 - 6.6 5.1 15.6 7.7 4.9 15.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 RPOL_N PF14700.6 RUS89681.1 - 8.5 5.7 26.1 11 5.3 26.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal SID-1_RNA_chan PF13965.6 RUS89681.1 - 8.6 4.6 5.6 9.1 4.5 5.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 RUS89681.1 - 9.3 5.0 7.9 13 4.6 7.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Otopetrin PF03189.13 RUS89681.1 - 9.3 4.9 9.3 11 4.7 9.3 1.1 1 0 0 1 1 1 0 Otopetrin ASC PF00858.24 RUS89681.1 - 9.9 5.0 9.9 12 4.7 9.9 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3106 PF11304.8 RUS89682.1 - 0.18 12.3 6.7 0.86 10.1 1.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3106) DUF5595 PF18077.1 RUS89683.1 - 0.39 10.8 14.9 25 5.0 1.6 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF5595) DSS1_SEM1 PF05160.13 RUS89683.1 - 7.8 6.6 17.7 82 3.4 0.9 5.7 1 1 4 5 5 5 0 DSS1/SEM1 family Anti-TRAP PF15777.5 RUS89685.1 - 0.046 13.7 1.6 2.1 8.4 0.5 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein 7tm_1 PF00001.21 RUS89686.1 - 3.6e-19 69.1 8.9 4.3e-19 68.9 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS89686.1 - 2e-08 34.3 11.3 2.8e-07 30.5 11.3 2.0 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 RUS89686.1 - 4.1e-05 23.0 0.3 8.7e-05 21.9 0.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4381 PF14316.6 RUS89686.1 - 0.15 12.3 1.2 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3432 PF11914.8 RUS89687.1 - 0.0017 18.6 16.9 0.012 15.9 12.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) Glyco_hydro_72 PF03198.14 RUS89687.1 - 0.14 11.3 5.3 19 4.4 0.3 3.9 1 1 3 4 4 4 0 Glucanosyltransferase zf-C5HC2 PF02928.16 RUS89688.1 - 0.0037 17.6 30.7 4 7.9 0.5 5.9 1 1 4 5 5 5 4 C5HC2 zinc finger KMP11 PF03037.16 RUS89688.1 - 0.037 14.8 9.8 11 6.9 0.2 3.3 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 Hepsin-SRCR PF09272.10 RUS89688.1 - 0.2 12.2 17.2 15 6.1 17.2 3.1 1 1 0 1 1 1 0 Hepsin, SRCR domain NDUF_B7 PF05676.13 RUS89688.1 - 0.31 10.8 19.2 6.4 6.6 0.3 4.7 1 1 7 8 8 8 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Thyroglobulin_1 PF00086.18 RUS89688.1 - 0.38 10.5 11.4 7.2e+03 -3.2 11.4 4.5 1 1 0 1 1 1 0 Thyroglobulin type-1 repeat EOS1 PF12326.8 RUS89689.1 - 0.006 16.5 0.9 0.0088 16.0 0.9 1.4 1 0 0 1 1 1 1 N-glycosylation protein CLN3 PF02487.17 RUS89689.1 - 0.022 13.8 0.2 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 RUS89689.1 - 0.024 14.7 0.6 0.024 14.7 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 RUS89689.1 - 0.17 10.8 0.2 0.21 10.5 0.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_polI_A34 PF08208.11 RUS89689.1 - 0.2 11.8 52.3 0.37 10.9 52.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 RUS89689.1 - 0.28 11.5 32.3 0.4 11.0 32.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 RUS89689.1 - 0.4 10.8 7.6 0.55 10.3 7.6 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 RUS89689.1 - 0.56 10.0 23.7 0.71 9.6 23.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Jak1_Phl PF17887.1 RUS89689.1 - 0.58 10.1 21.6 1 9.3 21.6 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain RNA_pol_Rpc4 PF05132.14 RUS89689.1 - 1.3 9.5 21.8 1.9 8.9 21.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 AXIN1_TNKS_BD PF16646.5 RUS89689.1 - 2.3 9.2 10.0 7.9 7.5 10.0 1.9 1 1 0 1 1 1 0 Axin-1 tankyrase binding domain DUF3807 PF12720.7 RUS89689.1 - 2.3 8.4 27.6 3.5 7.9 27.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.13 RUS89689.1 - 4.6 7.1 30.8 6.8 6.5 30.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SpoIIP PF07454.11 RUS89689.1 - 4.9 6.5 21.1 6.2 6.2 21.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_11 PF13086.6 RUS89689.1 - 5.5 6.7 17.0 8.7 6.0 17.0 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 RUS89689.1 - 6 5.5 13.5 8 5.1 13.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 RUS89689.1 - 7.4 6.6 15.9 11 6.1 15.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Somatomedin_B PF01033.17 RUS89690.1 - 1.2e-06 28.8 13.9 1.2e-06 28.8 13.9 2.5 2 0 0 2 2 2 1 Somatomedin B domain DMAP1 PF05499.12 RUS89692.1 - 4.9e-68 228.2 7.1 1.2e-67 226.9 7.1 1.7 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 RUS89692.1 - 4.9e-32 110.0 3.4 1.1e-31 108.9 3.4 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Borrelia_P83 PF05262.11 RUS89692.1 - 0.031 12.8 5.7 0.044 12.3 5.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CemA PF03040.14 RUS89692.1 - 0.88 9.5 2.6 34 4.3 0.0 2.2 2 0 0 2 2 2 0 CemA family Atg14 PF10186.9 RUS89692.1 - 1.8 7.6 11.7 0.48 9.5 8.1 1.9 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CUB PF00431.20 RUS89693.1 - 2e-11 44.2 0.0 4.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 RUS89693.1 - 1.4e-07 31.6 12.1 2.7e-07 30.7 12.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TMEM132D_C PF15706.5 RUS89693.1 - 0.0036 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DAP10 PF07213.11 RUS89693.1 - 0.032 14.2 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Crisp PF08562.10 RUS89693.1 - 1.1 9.8 6.5 2.3 8.9 6.5 1.4 1 0 0 1 1 1 0 Crisp Hexapep PF00132.24 RUS89694.1 - 2.6e-14 52.3 9.2 53 3.8 0.0 11.7 12 0 0 12 12 12 0 Bacterial transferase hexapeptide (six repeats) Peptidase_M27 PF01742.17 RUS89694.1 - 0.0018 17.5 4.0 30 3.6 0.1 4.9 1 1 7 8 8 8 4 Clostridial neurotoxin zinc protease RNA_pol_A_CTD PF03118.15 RUS89694.1 - 0.083 12.7 42.3 44 3.9 0.1 11.2 1 1 11 12 12 12 0 Bacterial RNA polymerase, alpha chain C terminal domain PPL4 PF18188.1 RUS89694.1 - 2.6 8.0 15.5 26 4.7 0.7 5.0 1 1 3 4 4 4 0 Prim-pol 4 LCAT PF02450.15 RUS89695.1 - 4.3e-70 236.9 0.0 4e-57 194.2 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 RUS89695.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 RUS89695.1 - 0.052 13.3 0.0 2.6 7.7 0.0 2.4 2 1 1 3 3 3 0 PGAP1-like protein zf-H2C2_2 PF13465.6 RUS89699.1 - 5.6e-14 51.8 24.5 1.4e-08 34.8 0.7 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS89699.1 - 2.1e-12 46.7 23.6 0.00013 22.3 0.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89699.1 - 3.8e-09 36.6 21.8 0.0014 19.3 5.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS89699.1 - 0.0015 18.5 8.6 0.015 15.3 2.8 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 RUS89699.1 - 0.0099 15.8 14.2 1.4 8.9 0.4 3.6 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-Di19 PF05605.12 RUS89699.1 - 1 9.7 6.3 1.1 9.6 4.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS89699.1 - 4.8 7.7 13.9 2.2 8.8 1.9 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type 7tm_1 PF00001.21 RUS89700.1 - 4.1e-14 52.5 0.0 4.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-AN1 PF01428.16 RUS89702.1 - 1.6 8.9 6.7 0.68 10.2 1.2 2.4 3 0 0 3 3 3 0 AN1-like Zinc finger BTB PF00651.31 RUS89703.1 - 6.4e-22 77.9 0.0 1.2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 RUS89703.1 - 4.9e-20 70.9 3.7 2.9e-08 33.1 0.1 5.7 6 0 0 6 6 6 3 Kelch motif BACK PF07707.15 RUS89703.1 - 1.2e-16 60.6 1.1 5.7e-16 58.5 0.5 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 RUS89703.1 - 4.2e-16 58.6 0.1 2.3e-05 24.5 0.0 5.2 3 1 2 5 5 5 3 Kelch motif Kelch_5 PF13854.6 RUS89703.1 - 1.8e-12 46.9 0.5 0.0056 16.6 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 RUS89703.1 - 4.8e-09 36.1 0.0 0.0014 18.6 0.0 5.3 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.6 RUS89703.1 - 1.3e-06 28.5 4.8 0.26 11.6 0.0 5.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS89703.1 - 2.1e-05 24.3 5.2 0.43 10.6 0.0 4.3 5 0 0 5 5 5 2 Kelch motif P4Ha_N PF08336.11 RUS89704.1 - 3e-35 121.2 0.3 6e-35 120.2 0.3 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 RUS89704.1 - 2.1e-15 57.4 0.1 4.1e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 RUS89704.1 - 1.3e-07 32.0 0.0 2.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SIR2 PF02146.17 RUS89705.1 - 2.4e-24 86.2 1.2 7.4e-21 74.9 0.0 2.7 2 1 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 RUS89705.1 - 0.0046 16.7 0.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain ECSIT PF06239.11 RUS89706.1 - 6.6e-70 234.7 1.3 1.4e-69 233.7 1.3 1.4 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 RUS89706.1 - 4.8e-36 124.0 1.3 5.9e-36 123.7 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein Utp12 PF04003.12 RUS89707.1 - 0.00023 21.4 0.5 0.0018 18.6 0.3 2.4 2 1 0 2 2 2 1 Dip2/Utp12 Family CK2S PF15011.6 RUS89707.1 - 0.082 12.8 2.1 2.4 8.0 0.0 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate NDUFB10 PF10249.9 RUS89708.1 - 2.7e-49 166.9 5.5 3.1e-49 166.6 5.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRE1 PF08647.11 RUS89709.1 - 7.8e-17 61.1 7.6 7.8e-17 61.1 7.6 11.2 5 3 4 10 10 10 1 BRE1 E3 ubiquitin ligase Filament PF00038.21 RUS89709.1 - 0.00022 20.9 13.5 0.00022 20.9 13.5 7.5 3 2 3 6 6 6 2 Intermediate filament protein Cdc13_OB2 PF18691.1 RUS89709.1 - 0.7 10.0 8.1 0.6 10.2 2.9 2.7 2 0 0 2 2 2 0 Cell division control protein 13, OB2 domain RabGAP-TBC PF00566.18 RUS89710.1 - 8e-39 133.5 1.5 1.1e-38 133.0 1.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 RUS89710.1 - 2.2e-08 33.8 0.6 0.0029 17.1 0.0 2.5 1 1 0 2 2 2 2 Rab-binding domain (RBD) Stealth_CR4 PF17103.5 RUS89710.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 HtrL_YibB PF09612.10 RUS89711.1 - 3e-13 49.9 0.0 4.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) zf-C3HC4 PF00097.25 RUS89712.1 - 3.8e-09 36.3 9.0 6.4e-09 35.5 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.30 RUS89712.1 - 4.7e-09 36.6 0.0 9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 RUS89712.1 - 3.8e-08 33.1 5.1 5.8e-08 32.5 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS89712.1 - 6e-07 29.7 8.7 1e-06 29.0 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RUS89712.1 - 8.3e-06 25.7 4.8 1.4e-05 25.0 2.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RUS89712.1 - 1.5e-05 24.7 10.2 3.2e-05 23.7 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 RUS89712.1 - 2e-05 24.6 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.6 RUS89712.1 - 0.00011 22.3 8.9 0.00021 21.4 8.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RUS89712.1 - 0.00057 19.7 6.2 0.001 18.9 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RUS89712.1 - 0.0021 17.8 4.1 0.0043 16.8 4.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 RUS89712.1 - 0.0038 17.2 8.4 0.0065 16.4 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS89712.1 - 0.0051 17.1 2.9 0.0098 16.2 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 RUS89712.1 - 0.0089 16.0 3.5 0.03 14.2 1.7 2.3 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 RUS89712.1 - 0.011 15.7 2.4 0.03 14.4 2.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAM_3 PF18016.1 RUS89712.1 - 0.031 14.1 0.1 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) zf-RING_10 PF16685.5 RUS89712.1 - 0.036 14.2 5.6 0.064 13.4 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 SAM_PNT PF02198.16 RUS89712.1 - 0.041 13.9 2.6 0.086 12.8 0.2 2.5 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Bac_export_2 PF01312.19 RUS89712.1 - 0.48 9.6 2.7 1 8.5 2.5 1.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Zn_ribbon_17 PF17120.5 RUS89712.1 - 1.5 8.5 6.1 2.9 7.6 6.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RRM_1 PF00076.22 RUS89714.1 - 1.7e-23 82.2 0.0 5.2e-10 39.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 RUS89715.1 - 1.4e-11 43.1 14.2 3.8e-05 22.9 0.2 5.5 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 RUS89715.1 - 9.2e-11 40.8 9.5 0.00017 21.2 0.7 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 RUS89715.1 - 4.4e-09 36.0 13.6 2.1e-06 27.5 0.3 4.6 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.6 RUS89715.1 - 5.7e-07 29.9 13.0 0.013 15.9 0.1 4.6 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS89715.1 - 4e-06 26.1 14.2 0.00083 18.8 2.9 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 RUS89715.1 - 0.068 13.1 3.2 1.6 8.8 0.3 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PCNA_C PF02747.15 RUS89716.1 - 1.7e-59 199.6 0.1 5.1e-59 198.0 0.1 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 RUS89716.1 - 2.4e-55 185.6 2.2 2.4e-55 185.6 2.2 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 RUS89716.1 - 2.5e-07 30.4 0.8 3e-07 30.2 0.8 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 RUS89716.1 - 6.7e-07 28.6 1.1 5e-05 22.5 1.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 RUS89716.1 - 0.0029 16.8 0.2 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein Tma16 PF11176.8 RUS89717.1 - 4.7e-36 123.8 6.4 5.8e-36 123.6 6.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF3892 PF13031.6 RUS89717.1 - 0.039 14.6 0.8 1.1 9.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3892) Ribosomal_L12 PF00542.19 RUS89718.1 - 2e-18 66.5 8.4 2e-18 66.5 8.4 2.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RUS89718.1 - 5.8e-15 54.7 4.9 3.1e-14 52.4 0.8 2.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Anophelin PF10731.9 RUS89718.1 - 0.0044 16.9 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 Thrombin inhibitor from mosquito DUF4479 PF14794.6 RUS89718.1 - 0.6 10.0 3.7 1.2 9.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) SHMT PF00464.19 RUS89719.1 - 1.7e-198 659.2 0.0 2e-198 658.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Cluap1 PF10234.9 RUS89720.1 - 8e-115 382.8 12.0 8e-115 382.8 12.0 1.4 2 0 0 2 2 2 1 Clusterin-associated protein-1 Ndc80_HEC PF03801.13 RUS89720.1 - 0.016 14.9 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 HEC/Ndc80p family Exonuc_VII_L PF02601.15 RUS89720.1 - 0.064 12.8 8.9 0.092 12.3 8.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.6 RUS89720.1 - 0.54 10.4 26.8 3.2 7.9 4.9 2.6 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lebercilin PF15619.6 RUS89720.1 - 0.67 9.6 24.5 0.18 11.4 17.7 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 RUS89720.1 - 1.3 6.8 14.4 1.8 6.4 14.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 RUS89720.1 - 3.8 7.9 23.1 11 6.4 22.6 1.9 1 1 0 1 1 1 0 Fez1 DUF4407 PF14362.6 RUS89720.1 - 6.2 6.1 12.9 9.6 5.5 12.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 RUS89720.1 - 7.6 6.6 16.4 3.5e+02 1.2 16.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Ras PF00071.22 RUS89721.1 - 1.3e-54 184.1 0.0 1.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS89721.1 - 9.7e-23 80.7 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS89721.1 - 3.6e-08 33.1 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 RUS89721.1 - 0.071 12.9 0.2 0.69 9.6 0.0 2.5 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 RUS89722.1 - 5.3e-14 52.4 15.9 0.00035 21.3 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS89722.1 - 1.1e-08 35.3 0.3 0.022 15.1 0.0 4.2 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 RUS89722.1 - 0.0033 16.7 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Nup160 PF11715.8 RUS89722.1 - 0.021 13.5 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 RUS89723.1 - 1.6e-55 188.2 0.0 2.1e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89723.1 - 2.8e-23 82.6 0.0 4.9e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Comm PF15957.5 RUS89723.1 - 0.16 12.4 0.2 0.37 11.2 0.0 1.7 2 0 0 2 2 2 0 Commissureless Sec7 PF01369.20 RUS89724.1 - 3.4e-71 238.7 0.0 4.8e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 RUS89724.1 - 6.3e-29 100.6 0.1 1.4e-28 99.5 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RUS89724.1 - 6.7e-09 36.1 0.1 1.3e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RUS89724.1 - 0.023 14.8 0.1 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 PH domain PH_16 PF17838.1 RUS89724.1 - 0.04 13.8 0.8 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 PH domain PH_8 PF15409.6 RUS89724.1 - 0.054 13.8 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain UCH PF00443.29 RUS89725.1 - 2.4e-49 168.2 3.8 2.4e-49 168.2 3.8 2.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS89725.1 - 4e-24 85.8 5.8 4e-24 85.8 5.8 2.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF2226 PF09987.9 RUS89726.1 - 0.013 14.9 0.9 0.013 14.8 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) PilJ PF13675.6 RUS89726.1 - 0.057 13.5 5.7 0.72 9.9 1.7 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4047 PF13256.6 RUS89726.1 - 0.06 13.5 2.2 0.079 13.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) RRF PF01765.19 RUS89726.1 - 0.06 13.3 3.8 0.087 12.8 3.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor AAA-ATPase_like PF09820.9 RUS89726.1 - 0.077 12.4 3.5 0.087 12.2 3.5 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase AcylCoA_dehyd_C PF12186.8 RUS89726.1 - 0.09 12.9 5.4 0.22 11.7 0.7 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Band_7_1 PF13421.6 RUS89726.1 - 0.11 12.2 1.3 0.13 11.9 1.3 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family HTH_53 PF18606.1 RUS89726.1 - 0.12 12.1 1.0 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain CCDC-167 PF15188.6 RUS89726.1 - 0.17 12.3 8.6 0.099 13.0 6.2 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 HSCB_C PF07743.13 RUS89726.1 - 0.19 12.2 12.1 0.3 11.6 6.8 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Spectrin_like PF18373.1 RUS89726.1 - 0.24 11.5 7.1 0.17 12.0 4.7 1.8 1 1 1 2 2 2 0 Spectrin like domain YjfB_motility PF14070.6 RUS89726.1 - 0.31 11.2 3.2 0.22 11.7 0.5 2.1 2 1 0 2 2 2 0 Putative motility protein CwsA PF10814.8 RUS89726.1 - 0.37 11.0 2.0 1.4 9.1 0.5 2.0 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA Flu_M1_C PF08289.11 RUS89726.1 - 0.61 10.3 5.2 1.7 8.9 2.5 2.2 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Metal_resist PF13801.6 RUS89726.1 - 3.7 7.8 10.5 5.9 7.1 1.8 2.2 1 1 1 2 2 2 0 Heavy-metal resistance Otopetrin PF03189.13 RUS89727.1 - 0.00034 19.6 2.8 0.056 12.3 0.0 3.7 1 1 1 2 2 2 1 Otopetrin Amino_oxidase PF01593.24 RUS89728.1 - 4.9e-48 164.5 0.0 8.4e-47 160.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS89728.1 - 1.3e-12 47.8 0.1 3.7e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS89728.1 - 1.5e-08 34.6 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS89728.1 - 2.6e-08 33.4 0.0 4.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS89728.1 - 4e-07 29.5 0.0 5.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 RUS89728.1 - 1.8e-05 24.0 0.1 9.1e-05 21.7 0.1 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 RUS89728.1 - 3.1e-05 24.0 0.1 0.0031 17.5 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 RUS89728.1 - 0.00012 20.9 0.1 0.00083 18.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 RUS89728.1 - 0.00013 21.5 0.2 0.00019 20.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS89728.1 - 0.00098 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RUS89728.1 - 0.0013 19.3 0.1 0.0028 18.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RUS89728.1 - 0.0051 15.9 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 RUS89728.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 RUS89728.1 - 0.028 13.7 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 RUS89728.1 - 0.031 13.5 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Reticulon PF02453.17 RUS89730.1 - 0.0014 18.6 3.7 0.0023 17.9 3.7 1.3 1 0 0 1 1 1 1 Reticulon UQ_con PF00179.26 RUS89731.1 - 9e-38 129.1 0.0 1.2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RUS89731.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Voltage_CLC PF00654.20 RUS89732.1 - 2.2e-93 313.3 26.2 2.2e-93 313.3 26.2 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RUS89732.1 - 6.6e-10 39.3 0.1 0.00016 22.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain Sin_N PF04801.13 RUS89733.1 - 1.6e-130 436.2 1.7 2e-130 435.9 1.7 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region TFIIA PF03153.13 RUS89736.1 - 0.17 11.8 5.3 0.21 11.6 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit API5 PF05918.11 RUS89736.1 - 7.2 5.3 7.1 10 4.8 7.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SNF PF00209.18 RUS89737.1 - 9.3e-168 559.2 15.4 1.5e-155 518.9 9.3 2.3 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Glyco_transf_92 PF01697.27 RUS89738.1 - 1.8e-38 132.7 0.0 2.3e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS89738.1 - 0.00019 21.9 0.0 0.00044 20.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 T3RM_EcoP15I_C PF18273.1 RUS89738.1 - 0.19 12.1 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain Glyco_transf_92 PF01697.27 RUS89739.1 - 8.4e-32 110.8 0.0 1.4e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS89739.1 - 0.0066 16.9 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DEK_C PF08766.11 RUS89740.1 - 4.6e-09 36.1 1.2 1.1e-08 34.8 1.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain DSPc PF00782.20 RUS89740.1 - 0.00016 21.5 0.0 0.00041 20.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain VPS9 PF02204.18 RUS89740.1 - 0.12 12.6 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain GAF PF01590.26 RUS89741.1 - 1.9e-06 28.5 0.0 8e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 GAF domain Dpy-30 PF05186.13 RUS89741.1 - 0.0024 17.5 0.5 0.039 13.6 0.2 2.6 2 0 0 2 2 2 1 Dpy-30 motif EF-hand_6 PF13405.6 RUS89741.1 - 0.0032 17.3 1.4 0.012 15.4 0.6 2.5 2 0 0 2 2 2 1 EF-hand domain DUF4559 PF15112.6 RUS89741.1 - 0.017 14.8 0.7 0.04 13.6 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3619 PF12279.8 RUS89741.1 - 0.023 15.0 0.3 0.092 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) FAD_SOX PF18371.1 RUS89741.1 - 0.072 13.4 0.2 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase EF-hand_1 PF00036.32 RUS89741.1 - 0.096 12.3 3.4 0.12 12.0 1.3 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 RUS89741.1 - 0.42 11.1 5.4 0.67 10.4 0.6 3.6 3 1 1 4 4 4 0 EF-hand domain pair SH3_2 PF07653.17 RUS89742.1 - 8.6e-13 47.8 0.0 1.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS89742.1 - 2.9e-09 36.7 0.3 3.4e-08 33.2 0.1 2.5 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RUS89742.1 - 7.2e-08 31.9 0.3 4.1e-06 26.3 0.0 2.8 2 1 0 2 2 2 1 SH3 domain fn3 PF00041.21 RUS89744.1 - 4.7e-07 30.1 0.7 0.0088 16.4 0.6 3.2 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS89744.1 - 0.05 14.2 0.6 1.3 9.7 0.6 2.8 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF2019 PF09450.10 RUS89744.1 - 0.072 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) SH3_9 PF14604.6 RUS89745.1 - 1e-10 41.3 0.1 1.8e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS89745.1 - 4.1e-08 32.8 0.0 7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS89745.1 - 0.00029 20.4 0.0 0.00064 19.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain V_ATPase_I PF01496.19 RUS89745.1 - 0.11 10.4 2.4 0.13 10.2 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HOOK PF05622.12 RUS89745.1 - 0.29 9.2 21.2 0.41 8.7 21.2 1.1 1 0 0 1 1 1 0 HOOK protein U79_P34 PF03064.16 RUS89745.1 - 1.1 8.5 9.6 3.9 6.8 9.5 1.9 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Tho2 PF11262.8 RUS89745.1 - 5.2 6.2 8.1 8.3 5.5 8.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nop14 PF04147.12 RUS89746.1 - 0.015 13.5 47.7 0.024 12.9 47.7 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS89746.1 - 0.039 13.4 51.5 0.054 12.9 51.5 1.2 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 RUS89746.1 - 0.65 8.7 13.0 1.1 8.0 13.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 RUS89746.1 - 3.6 6.8 49.9 4.5 6.5 49.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RUS89747.1 - 0.00016 21.2 45.2 0.0002 20.9 45.2 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 RUS89747.1 - 7.7 4.8 50.0 10 4.5 50.0 1.2 1 0 0 1 1 1 0 Mpp10 protein GAS PF13851.6 RUS89748.1 - 0.0071 15.7 17.3 0.0083 15.5 17.3 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 RUS89748.1 - 0.027 14.1 9.1 0.027 14.1 9.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 RUS89748.1 - 0.029 14.8 18.4 0.039 14.4 16.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HALZ PF02183.18 RUS89748.1 - 0.03 14.5 9.4 5.8 7.2 0.1 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4164 PF13747.6 RUS89748.1 - 0.035 14.4 8.9 0.073 13.4 8.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) SPATA24 PF15175.6 RUS89748.1 - 0.035 14.0 12.8 0.042 13.8 12.8 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF2175 PF09943.9 RUS89748.1 - 0.06 13.6 5.9 0.11 12.8 5.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) AMP-binding_C_2 PF14535.6 RUS89748.1 - 0.081 13.3 3.3 0.21 11.9 2.5 2.0 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain DUF5595 PF18077.1 RUS89748.1 - 0.1 12.7 8.2 0.17 12.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF812 PF05667.11 RUS89748.1 - 0.17 10.8 18.7 0.18 10.7 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cnn_1N PF07989.11 RUS89748.1 - 0.28 11.4 14.6 1.7 8.9 5.3 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 RUS89748.1 - 0.37 10.6 18.8 0.33 10.7 2.3 2.5 1 1 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 RUS89748.1 - 0.82 9.7 6.3 1.6 8.8 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 RUS89748.1 - 1.2 9.1 11.7 0.25 11.4 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) GCN5L1 PF06320.13 RUS89748.1 - 1.5 9.0 16.0 1.7 8.8 8.9 2.0 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Phlebovirus_NSM PF07246.11 RUS89748.1 - 1.6 8.1 8.4 1.9 7.8 8.4 1.2 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M APG6_N PF17675.1 RUS89748.1 - 1.7 9.2 20.4 4.2 7.9 20.4 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 RUS89748.1 - 1.8 9.0 5.1 22 5.5 0.2 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) SurA_N_2 PF13623.6 RUS89748.1 - 2.9 7.7 11.8 1 9.2 1.9 2.1 1 1 1 2 2 2 0 SurA N-terminal domain YabA PF06156.13 RUS89748.1 - 3 8.5 9.8 1.7 9.3 1.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4055 PF13264.6 RUS89748.1 - 3.7 7.7 10.0 10 6.2 10.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) TMF_DNA_bd PF12329.8 RUS89749.1 - 0.0014 18.6 27.1 0.39 10.7 3.6 3.6 2 2 1 3 3 3 3 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 RUS89749.1 - 0.0045 17.1 6.1 0.0045 17.1 6.1 4.0 3 1 1 4 4 3 2 bZIP transcription factor TSC22 PF01166.18 RUS89749.1 - 0.0048 17.2 10.5 0.2 12.0 0.6 4.2 2 1 1 3 3 3 1 TSC-22/dip/bun family GIT_CC PF16559.5 RUS89749.1 - 0.011 15.5 11.0 0.064 13.1 0.3 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Shugoshin_N PF07558.11 RUS89749.1 - 0.017 15.0 1.1 0.017 15.0 1.1 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Laminin_II PF06009.12 RUS89749.1 - 0.018 15.0 8.2 0.27 11.3 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II UPF0242 PF06785.11 RUS89749.1 - 0.029 14.5 1.4 0.029 14.5 1.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 RUS89749.1 - 0.037 14.7 14.6 0.25 12.0 0.9 3.4 2 2 1 3 3 3 0 Initiation control protein YabA BLOC1_2 PF10046.9 RUS89749.1 - 0.076 13.3 11.3 0.055 13.8 4.1 2.8 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 RUS89749.1 - 0.13 12.4 24.8 0.063 13.4 12.8 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG17 PF04108.12 RUS89749.1 - 0.23 10.5 8.4 0.36 9.9 1.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF2353 PF09789.9 RUS89749.1 - 0.24 10.7 14.9 2.5 7.4 9.0 2.2 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) SlyX PF04102.12 RUS89749.1 - 0.27 11.9 15.9 0.26 12.0 0.9 3.6 2 2 0 2 2 2 0 SlyX ZapB PF06005.12 RUS89749.1 - 0.33 11.4 25.4 0.16 12.5 4.5 3.5 2 2 1 3 3 3 0 Cell division protein ZapB AIG1 PF04548.16 RUS89749.1 - 0.44 9.8 4.0 0.086 12.2 0.4 1.5 2 0 0 2 2 2 0 AIG1 family Matrilin_ccoil PF10393.9 RUS89749.1 - 0.5 10.3 6.1 4.6 7.2 0.7 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CCDC92 PF14916.6 RUS89749.1 - 0.54 10.1 6.1 17 5.3 0.1 3.3 2 1 0 2 2 2 0 Coiled-coil domain of unknown function Fmp27_WPPW PF10359.9 RUS89749.1 - 0.57 9.0 15.9 0.014 14.3 5.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 RUS89749.1 - 0.62 9.4 19.3 1.6 8.0 12.4 2.1 1 1 1 2 2 2 0 FAM76 protein Swi5 PF07061.11 RUS89749.1 - 0.64 10.1 10.9 0.51 10.5 1.9 3.4 1 1 2 3 3 3 0 Swi5 GAS PF13851.6 RUS89749.1 - 0.79 9.0 27.1 0.02 14.2 13.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 RUS89749.1 - 1.3 9.2 30.6 0.26 11.4 5.2 4.2 3 1 1 4 4 4 0 Basic region leucine zipper FlaC_arch PF05377.11 RUS89749.1 - 1.4 9.3 5.2 5.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Herpes_UL6 PF01763.16 RUS89749.1 - 1.7 7.0 5.4 0.6 8.6 2.5 1.7 1 1 1 2 2 2 0 Herpesvirus UL6 like LURAP PF14854.6 RUS89749.1 - 1.9 8.5 5.7 7.3 6.6 0.4 3.2 2 1 2 4 4 4 0 Leucine rich adaptor protein Csm1_N PF18504.1 RUS89749.1 - 2 8.8 16.2 3 8.2 0.1 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain Sec34 PF04136.15 RUS89749.1 - 2 8.3 6.8 1.1 9.1 2.3 2.2 2 0 0 2 2 2 0 Sec34-like family DNA_pol3_alpha PF07733.12 RUS89749.1 - 2.8 7.4 6.5 0.29 10.7 0.4 1.9 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain FapA PF03961.13 RUS89749.1 - 2.8 6.4 15.8 5.8 5.4 9.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 RUS89749.1 - 3 6.6 23.2 0.98 8.2 11.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 RUS89749.1 - 3.2 6.2 11.6 6.9 5.1 11.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 RUS89749.1 - 3.3 7.5 20.7 0.058 13.2 8.9 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 RUS89749.1 - 5.5 6.2 16.8 0.28 10.5 5.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 RUS89749.1 - 5.7 7.1 23.4 1.8 8.7 3.9 2.7 2 1 0 2 2 2 0 Tropomyosin like PhoU PF01895.19 RUS89749.1 - 7.4 7.1 7.7 17 5.9 0.5 2.9 2 1 1 3 3 3 0 PhoU domain ABC_tran_CTD PF16326.5 RUS89749.1 - 9.6 6.5 21.2 14 6.0 2.4 3.1 2 2 0 2 2 2 0 ABC transporter C-terminal domain DUF1617 PF07761.12 RUS89750.1 - 0.019 15.1 2.1 0.042 13.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) K_channel_TID PF07941.11 RUS89750.1 - 0.4 11.2 6.3 17 6.0 0.0 3.8 4 1 1 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain GlutR_dimer PF00745.20 RUS89750.1 - 1.8 9.0 15.4 2.3 8.7 0.9 2.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RRM_1 PF00076.22 RUS89751.1 - 6.8e-14 51.4 0.2 9.9e-14 50.9 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P21-Arc PF04062.14 RUS89752.1 - 3.3e-81 271.5 0.1 3.6e-81 271.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CBM39 PF15886.5 RUS89754.1 - 3.1e-19 68.9 0.0 6.1e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 32) DUF5397 PF17375.2 RUS89754.1 - 0.18 11.5 0.0 13 5.6 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5397) FSA_C PF10479.9 RUS89754.1 - 8.4 4.4 10.4 12 3.9 10.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SAM_2 PF07647.17 RUS89755.1 - 1.6e-21 76.1 0.2 3.9e-09 36.5 0.0 3.0 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RUS89755.1 - 8.4e-17 61.4 0.4 7.3e-11 42.3 0.1 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 RUS89755.1 - 9.5e-09 35.9 0.0 3e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 TIR domain SAM_Ste50p PF09235.10 RUS89755.1 - 0.017 15.4 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Arm PF00514.23 RUS89755.1 - 0.026 14.6 0.6 3.9 7.6 0.2 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat cpYpsA PF12694.7 RUS89755.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family HEAT_2 PF13646.6 RUS89755.1 - 0.12 12.7 0.1 13 6.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Phage_lambda_P PF06992.11 RUS89755.1 - 0.18 11.5 0.6 3 7.5 0.1 2.5 2 0 0 2 2 2 0 Replication protein P MAP70 PF07058.11 RUS89756.1 - 0.23 10.1 3.6 0.23 10.2 3.6 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 2OG-FeII_Oxy_2 PF13532.6 RUS89757.1 - 6.9e-06 26.4 0.0 4.3e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TLD PF07534.16 RUS89758.1 - 1.4e-08 35.1 0.0 9.9e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 TLD DHHC PF01529.20 RUS89759.1 - 3e-35 121.3 11.5 4.3e-35 120.8 11.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase SurA_N_3 PF13624.6 RUS89759.1 - 0.2 11.4 0.7 0.36 10.6 0.7 1.3 1 0 0 1 1 1 0 SurA N-terminal domain NPR3 PF03666.13 RUS89760.1 - 1.1e-34 120.1 8.8 2.2e-29 102.6 6.9 2.5 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 RUS89760.1 - 2.2e-07 30.0 3.9 7e-07 28.4 3.9 1.8 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Tfb4 PF03850.14 RUS89761.1 - 2e-93 312.9 0.4 2.4e-93 312.6 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VKOR PF07884.14 RUS89762.1 - 2.8e-26 92.1 16.0 3.3e-26 91.9 16.0 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DUF4405 PF14358.6 RUS89762.1 - 0.24 12.0 0.0 0.24 12.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) SPC25 PF06703.11 RUS89762.1 - 0.24 11.2 6.7 0.45 10.3 0.2 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-C3HC4_3 PF13920.6 RUS89763.1 - 4.3e-12 45.7 8.3 7.2e-12 45.0 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS89763.1 - 1.1e-09 38.0 12.7 2.2e-09 37.0 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS89763.1 - 1.3e-09 38.2 11.9 2.7e-09 37.2 11.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RUS89763.1 - 4.9e-09 35.9 11.6 8.2e-09 35.2 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS89763.1 - 5.6e-09 35.9 8.1 1.3e-08 34.7 8.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS89763.1 - 1.8e-08 34.1 9.2 6.8e-08 32.2 9.2 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 RUS89763.1 - 6.3e-07 29.3 9.6 2.7e-06 27.2 10.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 RUS89763.1 - 2.4e-06 27.7 7.0 2.4e-06 27.7 7.0 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RUS89763.1 - 2.4e-06 27.6 11.4 4.8e-06 26.6 11.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 RUS89763.1 - 3.4e-05 23.6 2.9 7.5e-05 22.5 2.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 RUS89763.1 - 0.0036 17.3 4.0 0.0036 17.3 4.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 RUS89763.1 - 0.0047 16.5 5.3 0.0092 15.6 5.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TerY_C PF15616.6 RUS89763.1 - 0.026 14.6 0.5 0.026 14.6 0.5 1.9 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_11 PF17123.5 RUS89763.1 - 0.07 12.9 6.0 0.19 11.5 6.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 RUS89763.1 - 0.079 13.0 7.7 0.13 12.2 7.7 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.14 RUS89763.1 - 0.31 10.8 4.8 0.45 10.2 1.2 2.3 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.7 RUS89763.1 - 0.31 11.1 5.1 0.66 10.1 5.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon RecR PF02132.15 RUS89763.1 - 1 9.0 5.7 7.7 6.2 1.5 2.5 2 0 0 2 2 2 0 RecR protein zf-Nse PF11789.8 RUS89763.1 - 1.4 8.8 7.8 3.1 7.7 7.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RUS89763.1 - 7.3 6.5 11.5 69 3.4 12.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 RUS89763.1 - 8.1 6.4 5.3 15 5.5 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif TMEM132 PF16070.5 RUS89765.1 - 1.6e-93 313.8 1.0 2.2e-93 313.3 1.0 1.2 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 RUS89765.1 - 4.5e-19 68.0 0.0 9.3e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 RUS89765.1 - 5.4e-09 36.0 0.0 1.6e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Fungus-induced PF10917.8 RUS89765.1 - 0.016 15.5 0.4 0.041 14.2 0.4 1.6 1 0 0 1 1 1 0 Fungus-induced protein T2SS-T3SS_pil_N PF13629.6 RUS89765.1 - 0.031 14.0 0.3 0.087 12.6 0.3 1.8 1 0 0 1 1 1 0 Pilus formation protein N terminal region DUF5345 PF17280.2 RUS89765.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) zf-C2H2_jaz PF12171.8 RUS89766.1 - 0.045 14.1 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4407 PF14362.6 RUS89766.1 - 2.4 7.4 35.1 4 6.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) OmpH PF03938.14 RUS89766.1 - 5.4 7.4 51.4 6.4 7.1 24.1 4.3 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Med15 PF09606.10 RUS89767.1 - 9e-11 41.2 2.7 1.1e-10 40.9 2.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal KIX_2 PF16987.5 RUS89767.1 - 0.00049 20.0 2.5 0.00073 19.5 2.5 1.4 1 0 0 1 1 1 1 KIX domain OAD_gamma PF04277.13 RUS89767.1 - 0.25 12.0 0.4 0.25 12.0 0.4 2.2 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain V_ATPase_I PF01496.19 RUS89767.1 - 2.4 5.9 9.7 2.6 5.9 9.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IML1 PF12257.8 RUS89768.1 - 1.7e-106 355.5 0.0 2.5e-106 355.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 RUS89768.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf_Hakai PF18408.1 RUS89769.1 - 0.009 15.7 3.6 20 5.0 0.1 3.3 3 0 0 3 3 3 3 C2H2 Hakai zinc finger domain NFACT-R_2 PF18297.1 RUS89769.1 - 0.016 15.4 0.6 0.26 11.5 0.2 2.1 1 1 1 2 2 2 0 NFACT protein RNA binding domain PTR PF12789.7 RUS89769.1 - 0.024 14.7 19.6 0.6 10.2 9.1 3.3 1 1 2 3 3 3 0 Phage tail repeat like FUSC_2 PF13515.6 RUS89769.1 - 0.027 14.6 0.1 6.6 6.9 0.0 2.9 1 1 2 3 3 3 0 Fusaric acid resistance protein-like Vps39_1 PF10366.9 RUS89769.1 - 0.27 11.5 2.6 2.8 8.3 0.2 2.7 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 T3SS_needle_F PF09392.10 RUS89769.1 - 0.68 10.2 11.0 9.7 6.5 1.2 3.8 2 1 3 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF4808 PF16066.5 RUS89769.1 - 2.9 8.5 14.9 3.3 8.3 3.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4808) Mnd1 PF03962.15 RUS89770.1 - 2.1e-27 95.2 0.3 2.1e-27 95.2 0.3 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 RUS89770.1 - 5.9e-21 74.3 1.5 5.9e-21 74.3 1.5 2.7 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 RUS89770.1 - 0.001 19.4 0.4 0.0021 18.4 0.2 1.6 1 1 0 1 1 1 1 Penicillinase repressor DsrD PF08679.11 RUS89770.1 - 0.0044 17.2 0.1 0.0044 17.2 0.1 2.6 4 0 0 4 4 4 1 Dissimilatory sulfite reductase D (DsrD) V_ATPase_I PF01496.19 RUS89770.1 - 0.0072 14.3 2.4 0.0074 14.3 2.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 RUS89770.1 - 0.013 15.4 10.3 0.019 14.8 10.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 RUS89770.1 - 0.017 15.4 16.6 0.091 13.0 8.4 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 RUS89770.1 - 0.13 12.1 8.2 0.34 10.7 1.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.11 RUS89770.1 - 0.19 12.3 4.1 2.5 8.7 1.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 RUS89770.1 - 0.3 9.6 7.8 0.42 9.2 7.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 RUS89770.1 - 0.31 11.1 7.6 0.5 10.4 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 RUS89770.1 - 0.81 8.7 7.6 1.1 8.3 7.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pentapeptide_3 PF13576.6 RUS89771.1 - 2.5e-13 50.0 1.5 0.0022 18.1 0.0 3.7 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 RUS89771.1 - 3.5e-09 36.7 0.4 0.001 19.2 0.1 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) CfAFP PF05264.11 RUS89771.1 - 0.05 13.6 0.3 0.088 12.8 0.3 1.5 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) zf-C2H2_11 PF16622.5 RUS89772.1 - 3.9e-15 55.3 18.6 96 2.9 0.0 18.8 1 1 19 20 20 20 0 zinc-finger C2H2-type DUF600 PF04634.12 RUS89772.1 - 0.00023 21.2 3.0 67 3.5 0.1 6.2 1 1 7 8 8 8 0 Protein of unknown function, DUF600 PMG PF05287.12 RUS89772.1 - 0.006 16.7 29.6 0.81 9.7 3.7 4.3 2 1 1 4 4 4 4 PMG protein 7tm_2 PF00002.24 RUS89773.1 - 3.3e-12 46.2 15.1 5.1e-12 45.6 15.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentapeptide_4 PF13599.6 RUS89775.1 - 2.4e-05 24.4 7.1 0.007 16.5 3.1 2.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 RUS89776.1 - 8.8e-07 29.0 0.6 0.072 13.2 0.0 4.3 2 2 3 5 5 5 4 Pentapeptide repeats (9 copies) Hormone_4 PF00220.17 RUS89776.1 - 0.27 11.3 23.9 92 3.4 0.0 10.5 11 4 2 13 13 13 0 Neurohypophysial hormones, N-terminal Domain Inositol_P PF00459.25 RUS89776.1 - 7.1 6.1 5.1 1.5e+02 1.7 4.8 2.7 1 1 0 1 1 1 0 Inositol monophosphatase family Ion_trans_2 PF07885.16 RUS89777.1 - 2.9e-31 107.2 19.7 1.8e-16 59.9 2.0 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 RUS89777.1 - 0.053 12.7 10.3 0.11 11.7 0.5 2.2 2 0 0 2 2 2 0 Ion transport protein DUF229 PF02995.17 RUS89778.1 - 4.2e-96 322.5 1.0 5.2e-96 322.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS89778.1 - 1.6e-05 24.5 0.8 0.0009 18.7 0.0 2.4 1 1 1 2 2 2 2 Sulfatase Baculo_PEP_C PF04513.12 RUS89779.1 - 0.0071 16.4 10.6 0.49 10.4 0.2 3.4 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RUS89779.1 - 0.04 13.8 16.8 0.62 9.9 2.5 3.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4096 PF13340.6 RUS89779.1 - 0.11 12.8 9.3 30 4.9 0.1 6.7 5 2 3 8 8 8 0 Putative transposase of IS4/5 family (DUF4096) Spore_GerQ PF09671.10 RUS89779.1 - 1.7 8.7 6.8 83 3.3 0.0 4.8 4 2 3 7 7 7 0 Spore coat protein (Spore_GerQ) OmpH PF03938.14 RUS89779.1 - 2.8 8.3 11.6 5.4 7.3 4.0 2.6 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) eIF-5_eIF-2B PF01873.17 RUS89779.1 - 2.8 7.8 5.5 5.7 6.8 0.1 3.0 1 1 1 3 3 3 0 Domain found in IF2B/IF5 T3SS_needle_F PF09392.10 RUS89779.1 - 4.7 7.5 13.9 5.4 7.3 0.5 4.5 3 2 2 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF FAD-SLDH PF12318.8 RUS89779.1 - 10 6.2 21.7 0.3 11.2 3.6 3.0 1 1 1 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase CBM_14 PF01607.24 RUS89781.1 - 9.9e-10 38.4 13.2 3e-05 24.1 2.5 2.5 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain HSNSD PF12062.8 RUS89782.1 - 5.3e-103 345.4 0.6 3.1e-53 181.2 0.0 2.2 2 0 0 2 2 2 2 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 RUS89782.1 - 5e-30 104.9 1.3 5.8e-30 104.7 0.3 1.6 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS89782.1 - 2.2e-13 51.1 0.0 2e-05 25.1 0.0 2.7 1 1 1 2 2 2 2 Sulfotransferase family Glycos_transf_1 PF00534.20 RUS89783.1 - 6e-20 71.5 0.0 9.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RUS89783.1 - 4.1e-14 53.2 0.0 8.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RUS89783.1 - 4.7e-10 39.7 0.0 8.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATP_bind_1 PF03029.17 RUS89784.1 - 1.9e-79 266.8 0.1 2.5e-79 266.5 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 RUS89784.1 - 9.5e-07 28.5 0.1 4.4e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 RUS89784.1 - 2.6e-06 27.1 0.0 0.0017 18.0 0.0 2.5 2 1 0 2 2 2 2 Ras family FeoB_N PF02421.18 RUS89784.1 - 8.8e-06 25.3 0.0 0.00044 19.8 0.0 2.9 2 1 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RUS89784.1 - 0.00015 21.8 0.0 0.85 9.5 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase cobW PF02492.19 RUS89784.1 - 0.00027 20.6 0.2 0.0031 17.1 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 RUS89784.1 - 0.00031 19.8 0.1 0.6 9.1 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 RUS89784.1 - 0.00061 20.2 0.0 0.0012 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 RUS89784.1 - 0.00062 19.8 0.0 0.017 15.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RUS89784.1 - 0.00076 19.8 0.0 0.0078 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 RUS89784.1 - 0.0019 17.7 0.0 2 7.9 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family NACHT PF05729.12 RUS89784.1 - 0.0034 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 RUS89784.1 - 0.0035 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 RUS89784.1 - 0.0044 17.2 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 RUS89784.1 - 0.0062 16.2 0.0 0.11 12.1 0.0 2.5 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 RUS89784.1 - 0.011 16.0 0.3 0.12 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 RUS89784.1 - 0.013 15.3 0.0 0.046 13.5 0.0 2.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 RUS89784.1 - 0.013 16.1 0.0 0.055 14.0 0.0 2.2 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.17 RUS89784.1 - 0.015 15.4 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 RUS89784.1 - 0.019 14.7 0.2 0.084 12.6 0.0 2.2 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 RUS89784.1 - 0.019 15.1 0.0 0.061 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 RUS89784.1 - 0.019 14.1 0.0 6.1 5.9 0.1 2.4 2 1 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 RUS89784.1 - 0.024 14.1 0.6 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 RUS89784.1 - 0.048 13.4 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.10 RUS89784.1 - 0.057 12.9 0.1 0.39 10.1 0.0 2.2 2 1 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1_Xtn PF16897.5 RUS89784.1 - 0.061 13.3 0.0 13 5.9 0.0 2.5 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain CLP1_P PF16575.5 RUS89784.1 - 0.062 13.1 0.0 1.5 8.5 0.0 2.3 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3452 PF11934.8 RUS89784.1 - 0.09 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) PglZ PF08665.12 RUS89784.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 PglZ domain AAA_7 PF12775.7 RUS89784.1 - 0.097 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 RUS89784.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 RUS89784.1 - 0.19 11.8 2.5 11 6.1 0.0 3.5 2 1 1 3 3 3 0 Dynamin family Ras PF00071.22 RUS89787.1 - 7.1e-26 90.7 0.0 1.1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS89787.1 - 3.2e-19 69.3 0.0 4.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS89787.1 - 8.6e-07 28.6 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS89787.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS89787.1 - 0.16 11.5 0.1 1.9 8.0 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 RUS89787.1 - 0.16 11.6 0.0 1 9.0 0.0 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Cnd2 PF05786.14 RUS89788.1 - 0.0074 15.0 12.8 0.0069 15.1 12.8 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 NPR3 PF03666.13 RUS89788.1 - 0.022 13.6 9.5 0.028 13.2 9.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 RUS89788.1 - 0.32 9.0 40.6 0.46 8.5 40.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 RUS89788.1 - 4.9 7.4 14.6 6.4 7.1 14.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CNDH2_C PF16858.5 RUS89788.1 - 5.6 6.8 16.2 7.4 6.4 16.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 RUS89788.1 - 9.7 5.5 14.8 12 5.1 14.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) IRK_C PF17655.1 RUS89789.1 - 1.1e-55 188.0 0.0 1.5e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RUS89789.1 - 4.4e-46 156.2 0.4 7.5e-46 155.5 0.4 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RUS89789.1 - 7.4e-08 32.3 5.2 1.3e-07 31.4 5.2 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 RUS89789.1 - 0.00054 19.3 0.8 0.00074 18.8 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein IRK_C PF17655.1 RUS89790.1 - 1.2e-59 200.8 0.0 1.6e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 RUS89790.1 - 4.2e-45 153.1 0.2 6.5e-45 152.4 0.2 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 RUS89790.1 - 0.00049 20.0 5.7 0.0012 18.8 5.7 1.7 1 1 0 1 1 1 1 Ion channel Abhydrolase_3 PF07859.13 RUS89791.1 - 1.7e-40 139.1 0.0 2.4e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RUS89791.1 - 3.2e-06 26.8 0.0 9.7e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 RUS89791.1 - 8.6e-05 21.6 1.8 0.00023 20.2 0.9 2.0 2 1 0 2 2 2 1 Carboxylesterase family Lipoprotein_21 PF14041.6 RUS89791.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 LppP/LprE lipoprotein CCDC92 PF14916.6 RUS89792.1 - 1.3e-20 72.9 1.5 4.1e-20 71.3 0.4 2.4 2 0 0 2 2 2 1 Coiled-coil domain of unknown function Cast PF10174.9 RUS89792.1 - 1.2e-05 23.8 5.5 1.7e-05 23.3 5.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HMMR_N PF15905.5 RUS89792.1 - 0.00073 19.1 7.7 0.0014 18.2 7.7 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 RUS89792.1 - 0.0022 18.0 14.1 0.0029 17.6 12.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.16 RUS89792.1 - 0.0032 17.6 11.1 0.14 12.3 0.9 2.8 2 0 0 2 2 2 2 Hr1 repeat Golgin_A5 PF09787.9 RUS89792.1 - 0.0036 16.8 10.0 0.0058 16.1 10.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 YlqD PF11068.8 RUS89792.1 - 0.0075 16.6 2.6 0.0075 16.6 2.6 2.2 1 1 0 2 2 2 1 YlqD protein SKA1 PF07160.12 RUS89792.1 - 0.023 14.6 2.5 0.044 13.6 2.5 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 RUS89792.1 - 0.054 12.4 6.5 0.096 11.5 6.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.9 RUS89792.1 - 0.054 12.3 3.0 0.076 11.8 3.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cluap1 PF10234.9 RUS89792.1 - 0.091 12.2 8.5 2.1 7.7 7.8 2.1 1 1 0 1 1 1 0 Clusterin-associated protein-1 kleA_kleC PF17383.2 RUS89792.1 - 0.13 12.6 8.4 0.34 11.3 3.5 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A DUF4407 PF14362.6 RUS89792.1 - 0.19 11.1 5.0 0.36 10.1 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NleF_casp_inhib PF16809.5 RUS89792.1 - 0.21 11.5 1.4 0.33 10.9 1.4 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor Matrilin_ccoil PF10393.9 RUS89792.1 - 0.47 10.4 1.8 0.67 9.9 0.3 2.2 2 0 0 2 2 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Rootletin PF15035.6 RUS89792.1 - 0.52 10.3 14.8 1.3 9.0 14.8 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF812 PF05667.11 RUS89792.1 - 0.53 9.1 12.8 0.8 8.5 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF724 PF05266.14 RUS89792.1 - 0.58 10.0 6.8 1.1 9.1 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cep57_CLD PF14073.6 RUS89792.1 - 0.66 10.0 14.6 1.2 9.2 14.1 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 HIP1_clath_bdg PF16515.5 RUS89792.1 - 0.68 10.6 16.3 3.1 8.5 6.0 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF641 PF04859.12 RUS89792.1 - 0.75 10.1 10.7 2.5 8.5 3.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.20 RUS89792.1 - 0.86 9.6 10.9 0.76 9.8 2.5 3.1 2 1 1 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 RUS89792.1 - 1.1 8.8 7.3 1.8 8.1 7.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 RUS89792.1 - 1.8 9.0 7.4 1.1 9.7 1.2 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.6 RUS89792.1 - 2 8.7 8.7 4.2 7.7 2.4 3.6 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DivIVA PF05103.13 RUS89792.1 - 2.7 8.1 11.6 4.4 7.4 10.8 1.7 1 1 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.10 RUS89792.1 - 2.7 8.2 6.5 7 6.8 6.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 RUS89792.1 - 4.2 7.5 5.8 17 5.5 5.5 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 RUS89792.1 - 6.8 7.2 6.9 9.2 6.8 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4200 PF13863.6 RUS89792.1 - 8.9 6.7 19.1 13 6.2 14.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 RUS89792.1 - 9.3 7.0 12.0 11 6.7 0.4 3.6 1 1 2 3 3 3 0 SlyX CARD_2 PF16739.5 RUS89793.1 - 2.2e-11 43.6 0.0 4.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Dna2 PF08696.11 RUS89794.1 - 4.4e-58 196.5 0.0 5.5e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.7 RUS89794.1 - 2.7e-07 30.8 0.1 3.6e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 RUS89794.1 - 1.3e-05 25.3 0.2 0.0035 17.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF83 RepL PF05732.11 RUS89794.1 - 0.042 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Amidinotransf PF02274.17 RUS89794.1 - 0.12 11.5 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Amidinotransferase RseC_MucC PF04246.12 RUS89795.1 - 0.017 15.1 0.0 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PQQ_3 PF13570.6 RUS89795.1 - 0.17 12.4 0.1 0.38 11.3 0.1 1.6 1 0 0 1 1 1 0 PQQ-like domain SAP130_C PF16014.5 RUS89796.1 - 3e-32 112.2 10.5 3e-32 112.2 10.5 6.9 2 2 5 8 8 8 2 Histone deacetylase complex subunit SAP130 C-terminus T3SSipB PF16535.5 RUS89797.1 - 0.0027 18.2 11.5 0.0027 18.2 11.5 2.7 2 2 0 2 2 2 1 Type III cell invasion protein SipB DUF1664 PF07889.12 RUS89797.1 - 0.0039 17.2 7.4 0.0039 17.2 7.4 3.6 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) HAP1_N PF04849.13 RUS89797.1 - 0.0053 16.0 17.2 0.0053 16.0 17.2 2.9 2 2 0 2 2 2 1 HAP1 N-terminal conserved region CtIP_N PF10482.9 RUS89797.1 - 0.011 15.8 2.1 0.011 15.8 2.1 3.2 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF5082 PF16888.5 RUS89797.1 - 0.021 15.1 23.0 0.16 12.3 9.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) KASH_CCD PF14662.6 RUS89797.1 - 0.071 12.9 34.7 0.71 9.7 5.4 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 RUS89797.1 - 0.19 11.8 29.7 1.8 8.7 3.3 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 RUS89797.1 - 0.3 10.6 30.4 0.23 11.0 4.9 2.2 2 0 0 2 2 2 0 Leucine zipper Fez1 PF06818.15 RUS89797.1 - 0.45 11.0 30.4 0.42 11.0 17.5 2.2 2 0 0 2 2 2 0 Fez1 Lectin_N PF03954.14 RUS89797.1 - 0.5 10.1 16.6 4.8 6.9 0.4 3.1 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Csm1_N PF18504.1 RUS89797.1 - 0.75 10.2 27.0 3.1 8.2 3.6 4.5 2 2 2 4 4 4 0 Csm1 N-terminal domain Laminin_II PF06009.12 RUS89797.1 - 0.89 9.6 23.7 0.14 12.1 7.6 3.1 2 2 1 3 3 3 0 Laminin Domain II CLZ PF16526.5 RUS89797.1 - 2.3 8.7 30.1 0.43 11.0 6.3 4.4 3 2 2 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LOH1CR12 PF10158.9 RUS89797.1 - 2.5 8.1 12.9 0.2 11.7 4.8 2.7 2 1 1 3 3 3 0 Tumour suppressor protein APG6_N PF17675.1 RUS89797.1 - 2.5 8.6 37.5 0.18 12.3 14.2 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region TMEM192 PF14802.6 RUS89797.1 - 3 6.9 6.3 2.1 7.4 3.6 2.1 2 1 0 2 2 2 0 TMEM192 family DUF16 PF01519.16 RUS89797.1 - 3.1 8.3 24.8 8.5 6.9 0.7 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Mod_r PF07200.13 RUS89797.1 - 3.3 7.8 29.9 2.2 8.4 2.4 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 RUS89797.1 - 3.5 7.1 27.0 0.09 12.3 11.6 3.8 2 2 1 3 3 3 0 fzo-like conserved region GIT_CC PF16559.5 RUS89797.1 - 4.2 7.3 22.3 15 5.5 0.1 4.9 3 2 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor USP8_interact PF08941.10 RUS89797.1 - 4.7 7.0 17.8 5.3 6.8 4.3 3.1 2 1 1 3 3 3 0 USP8 interacting TMF_DNA_bd PF12329.8 RUS89797.1 - 5 7.2 39.2 0.064 13.3 2.5 4.4 4 2 0 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 RUS89797.1 - 5.5 6.8 31.1 1.3 8.9 6.0 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin_2 PF14523.6 RUS89797.1 - 8 6.9 19.9 4.8 7.6 12.9 2.7 2 0 0 2 2 2 0 Syntaxin-like protein QVR PF17064.5 RUS89798.1 - 1.9e-05 24.8 7.8 2.3e-05 24.5 7.8 1.1 1 0 0 1 1 1 1 Sleepless protein UPAR_LY6 PF00021.21 RUS89798.1 - 0.004 17.8 4.7 0.0082 16.8 4.7 1.6 1 1 0 1 1 1 1 u-PAR/Ly-6 domain QVR PF17064.5 RUS89799.1 - 2.7e-06 27.5 2.8 4.5e-06 26.8 2.8 1.3 1 0 0 1 1 1 1 Sleepless protein AAA_6 PF12774.7 RUS89800.1 - 1.7e-162 539.9 0.0 3.6e-161 535.6 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RUS89800.1 - 3e-151 504.1 4.4 1.3e-150 502.0 4.4 2.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RUS89800.1 - 1.1e-103 346.1 0.3 3.3e-103 344.6 0.3 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RUS89800.1 - 5.2e-92 306.9 0.4 5.2e-92 306.9 0.4 2.8 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RUS89800.1 - 1.5e-79 265.7 0.0 1.4e-77 259.3 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_C PF18199.1 RUS89800.1 - 3.8e-64 216.9 0.0 1.1e-63 215.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RUS89800.1 - 1.2e-60 204.1 0.0 3e-60 202.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RUS89800.1 - 4.2e-47 159.1 0.0 1.1e-45 154.5 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RUS89800.1 - 3.2e-43 148.1 7.4 7.5e-43 146.9 7.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 RUS89800.1 - 9.7e-36 122.7 0.2 3.8e-35 120.8 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RUS89800.1 - 1.2e-18 67.5 0.0 3.4e-06 27.1 0.0 5.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RUS89800.1 - 1.4e-18 67.0 1.2 2.3e-17 63.0 0.1 3.5 3 0 0 3 3 3 1 AAA+ lid domain AAA PF00004.29 RUS89800.1 - 7.5e-05 23.2 0.0 0.94 9.9 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RUS89800.1 - 0.00019 21.7 0.0 0.093 13.0 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 RUS89800.1 - 0.00046 20.6 0.0 1.5 9.2 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 RUS89800.1 - 0.00089 19.6 0.0 2.5 8.5 0.0 4.4 4 0 0 4 4 2 1 RNA helicase PhoH PF02562.16 RUS89800.1 - 0.0064 16.0 0.1 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 RUS89800.1 - 0.0065 15.6 0.0 0.021 13.9 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 RUS89800.1 - 0.078 13.5 0.3 4.4 7.9 0.0 3.8 3 0 0 3 3 2 0 AAA domain BLOC1_2 PF10046.9 RUS89800.1 - 2.9 8.3 13.6 0.84 10.0 2.3 4.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ARL2_Bind_BART PF11527.8 RUS89800.1 - 3.4 7.8 10.7 5.5 7.1 0.1 4.4 4 0 0 4 4 4 0 The ARF-like 2 binding protein BART WD40 PF00400.32 RUS89801.1 - 3.5e-18 65.6 12.9 0.00015 22.5 0.3 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS89801.1 - 4.2e-05 23.8 0.1 4.5 7.6 0.0 4.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 RUS89801.1 - 0.0005 19.9 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 RUS89801.1 - 0.0059 15.3 0.8 2.7 6.5 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS89801.1 - 0.0062 15.9 0.0 0.056 12.8 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain F-box-like PF12937.7 RUS89801.1 - 0.023 14.6 0.3 0.049 13.5 0.3 1.6 1 0 0 1 1 1 0 F-box-like G-patch PF01585.23 RUS89802.1 - 5.5e-12 45.4 0.6 1.2e-11 44.3 0.6 1.6 1 0 0 1 1 1 1 G-patch domain Ank_2 PF12796.7 RUS89802.1 - 1.1e-08 35.6 0.5 1.8e-08 34.8 0.5 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS89802.1 - 6.3e-08 32.7 1.1 1.7e-05 25.0 0.2 2.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89802.1 - 8.5e-07 28.8 0.0 0.004 17.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 RUS89802.1 - 1.9e-05 24.9 0.4 0.003 17.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RUS89802.1 - 0.00047 20.7 0.4 0.0084 16.7 0.1 2.5 1 1 2 3 3 3 1 Ankyrin repeats (many copies) G-patch_2 PF12656.7 RUS89802.1 - 0.21 11.7 0.4 0.56 10.3 0.4 1.8 1 0 0 1 1 1 0 G-patch domain RRM_1 PF00076.22 RUS89803.1 - 1.8e-31 107.8 0.1 3.9e-16 58.6 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS89803.1 - 9.1e-06 25.7 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 RUS89803.1 - 8.4e-05 22.4 0.0 0.69 9.8 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif DUF4614 PF15391.6 RUS89803.1 - 1.6 8.7 6.9 2.4 8.1 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tetraspanin PF00335.20 RUS89805.1 - 1.2e-60 205.1 6.3 1.3e-60 205.0 6.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2852 PF11014.8 RUS89805.1 - 0.16 12.1 0.4 0.37 11.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) ArfGap PF01412.18 RUS89806.1 - 1.1e-31 109.3 0.3 2.4e-31 108.3 0.3 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 RUS89806.1 - 2.3e-23 82.7 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RUS89806.1 - 1.5e-05 25.4 2.4 0.00032 21.1 0.1 3.2 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 RUS89806.1 - 3.8e-05 23.7 0.3 2.9 8.0 0.0 3.4 3 1 0 3 3 3 2 PH domain PH_8 PF15409.6 RUS89806.1 - 0.00088 19.5 3.4 0.25 11.6 0.7 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain MafB19-deam PF14437.6 RUS89806.1 - 0.13 12.0 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 MafB19-like deaminase MtaB PF12176.8 RUS89806.1 - 0.13 11.0 2.3 0.092 11.5 0.7 1.5 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit PH_17 PF18012.1 RUS89806.1 - 0.14 11.9 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 PH domain S4 PF01479.25 RUS89807.1 - 2.8e-11 42.9 2.3 1e-10 41.1 2.3 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 RUS89807.1 - 9.8e-07 29.6 1.6 1.5e-06 29.0 0.9 1.9 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Pkinase PF00069.25 RUS89808.1 - 2.6e-41 141.7 0.0 5.5e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 RUS89808.1 - 1.3e-40 138.5 0.4 3e-40 137.3 0.4 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 RUS89808.1 - 2.7e-25 89.1 0.0 4.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS89808.1 - 8.5e-06 24.8 0.0 2.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RUS89808.1 - 0.00094 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS89808.1 - 0.073 13.0 0.1 0.32 10.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family MMM1 PF10296.9 RUS89809.1 - 1.8e-06 27.2 1.3 6.7e-06 25.4 0.0 2.5 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 RUS89809.1 - 0.0017 18.9 0.0 0.0059 17.1 0.0 1.9 1 0 0 1 1 1 1 PH domain Peptidase_M1 PF01433.20 RUS89810.1 - 2.3e-80 269.3 2.0 3.7e-80 268.6 2.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 RUS89810.1 - 6.3e-69 232.9 0.2 9e-69 232.4 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 RUS89810.1 - 3.7e-42 144.6 0.3 7.2e-42 143.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain FoP_duplication PF13865.6 RUS89810.1 - 6.1 7.5 5.8 10 6.7 5.8 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Annexin PF00191.20 RUS89811.1 - 1.2e-79 262.3 8.6 5e-21 74.5 0.1 4.7 4 1 0 4 4 4 4 Annexin Nudc_N PF14050.6 RUS89812.1 - 9.4e-22 76.8 0.0 1.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 RUS89812.1 - 3.2e-13 50.5 0.8 5.6e-13 49.7 0.8 1.4 1 0 0 1 1 1 1 CS domain Presenilin PF01080.17 RUS89812.1 - 1.2 7.8 9.8 1.7 7.4 9.8 1.2 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 RUS89812.1 - 2.8 6.3 12.7 4 5.8 12.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PGAP1 PF07819.13 RUS89813.1 - 1.3e-71 241.0 0.1 1.6e-71 240.7 0.1 1.1 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 RUS89813.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 RUS89813.1 - 0.0012 19.5 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS89813.1 - 0.0087 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS89813.1 - 0.012 15.3 0.1 0.025 14.2 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 RUS89813.1 - 0.015 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 RUS89813.1 - 0.024 14.5 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2990 PF11693.8 RUS89813.1 - 0.13 12.4 0.0 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) DUF915 PF06028.11 RUS89813.1 - 0.22 10.8 0.5 16 4.7 0.4 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 RUS89814.1 - 2e-37 129.1 0.0 2.3e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 PGAP1-like protein Val_tRNA-synt_C PF10458.9 RUS89816.1 - 0.0065 16.7 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm PBP1_TM PF14812.6 RUS89816.1 - 0.24 11.8 17.5 0.5 10.8 2.6 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4407 PF14362.6 RUS89816.1 - 4.9 6.4 6.2 0.78 9.0 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MADF_DNA_bdg PF10545.9 RUS89817.1 - 9.4e-19 67.5 0.1 1.8e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS89817.1 - 0.0019 18.0 0.2 0.0039 17.0 0.2 1.5 1 0 0 1 1 1 1 BESS motif Myb_DNA-bind_4 PF13837.6 RUS89817.1 - 0.015 15.6 0.1 0.051 14.0 0.0 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PDDEXK_6 PF04720.12 RUS89817.1 - 0.028 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Cupin_7 PF12973.7 RUS89817.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 ChrR Cupin-like domain Myb_DNA-bind_2 PF08914.11 RUS89817.1 - 0.15 12.3 0.2 0.43 10.8 0.2 1.9 1 0 0 1 1 1 0 Rap1 Myb domain Tmem26 PF09772.9 RUS89818.1 - 2.5e-78 263.4 10.6 1.4e-77 260.9 10.6 1.8 1 1 0 1 1 1 1 Transmembrane protein 26 Tetraspanin PF00335.20 RUS89819.1 - 2.7e-22 79.6 11.5 3.8e-22 79.1 11.5 1.2 1 0 0 1 1 1 1 Tetraspanin family TcpE PF12648.7 RUS89819.1 - 1.4 9.5 9.5 2.3 8.8 3.9 2.8 3 0 0 3 3 3 0 TcpE family Trp_oprn_chp PF09534.10 RUS89819.1 - 1.9 8.3 6.3 2.9 7.7 6.3 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 7tm_1 PF00001.21 RUS89820.1 - 4.8e-51 173.6 9.0 6.6e-51 173.2 9.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS89820.1 - 1.8e-10 40.7 7.3 2.5e-10 40.2 7.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_A22B PF04258.13 RUS89820.1 - 0.00084 18.9 0.9 0.00084 18.9 0.9 1.8 2 1 0 2 2 2 1 Signal peptide peptidase Glycolipid_bind PF06475.11 RUS89820.1 - 0.19 11.2 0.2 14 5.1 0.1 2.5 3 0 0 3 3 3 0 Putative glycolipid-binding SafA PF17073.5 RUS89820.1 - 0.24 11.4 1.0 9.2 6.3 0.4 2.8 2 0 0 2 2 2 0 Two-component-system connector protein SSF PF00474.17 RUS89821.1 - 9.8e-40 136.6 26.6 1.2e-39 136.4 26.6 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Pox_A14 PF05767.12 RUS89821.1 - 2.4 8.4 11.4 1.2 9.3 0.2 4.2 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 SSF PF00474.17 RUS89822.1 - 5.6e-41 140.7 25.7 7e-41 140.4 25.7 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family 7tm_1 PF00001.21 RUS89823.1 - 7.6e-11 41.8 27.4 1e-10 41.4 27.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS89823.1 - 5.9e-07 29.1 13.4 5.9e-07 29.1 13.4 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS89823.1 - 0.00054 19.7 29.9 0.00054 19.7 29.9 2.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx p450 PF00067.22 RUS89824.1 - 5.4e-95 318.8 1.5 6.3e-95 318.6 1.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vac14_Fab1_bd PF12755.7 RUS89825.1 - 2.8e-13 50.3 0.9 0.21 12.2 0.0 7.0 5 2 3 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RUS89825.1 - 1.3e-10 40.6 12.7 1.5 9.3 0.0 10.5 12 0 0 12 12 10 2 HEAT repeat HEAT_2 PF13646.6 RUS89825.1 - 1.2e-09 38.4 0.0 0.0023 18.3 0.0 5.4 3 2 4 7 7 6 4 HEAT repeats Cnd1 PF12717.7 RUS89825.1 - 7.7e-09 35.8 5.7 0.00027 21.0 0.0 5.3 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS89825.1 - 2.8e-08 34.1 14.5 0.066 13.7 0.0 9.4 13 0 0 13 13 11 2 HEAT-like repeat CLASP_N PF12348.8 RUS89825.1 - 4e-08 33.1 0.2 0.17 11.4 0.0 4.7 3 1 1 4 4 4 2 CLASP N terminal Ecm29 PF13001.7 RUS89825.1 - 4.9e-06 25.5 2.1 0.33 9.6 0.0 4.6 3 2 2 5 5 5 2 Proteasome stabiliser MMS19_N PF14500.6 RUS89825.1 - 0.00021 21.0 1.9 0.02 14.5 0.0 4.1 5 1 1 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II U3snoRNP10 PF12397.8 RUS89825.1 - 0.026 14.9 3.6 1.3 9.4 0.2 3.9 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 IFRD PF05004.13 RUS89825.1 - 0.031 13.4 4.2 0.16 11.0 0.5 3.3 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Nucleocap_ssRNA PF11128.8 RUS89825.1 - 0.043 13.5 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid DRIM PF07539.12 RUS89825.1 - 0.059 11.7 6.4 0.26 9.5 0.1 3.1 4 0 0 4 4 4 0 Down-regulated in metastasis Xpo1 PF08389.12 RUS89825.1 - 0.1 12.7 1.5 4.3 7.4 0.0 3.6 3 0 0 3 3 3 0 Exportin 1-like protein EF-G-binding_N PF07299.11 RUS89825.1 - 0.11 13.0 1.0 1.1 9.8 0.0 3.2 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal LPD16 PF18830.1 RUS89825.1 - 0.16 11.9 0.4 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 16 UME PF08064.13 RUS89825.1 - 1.5 8.8 3.9 6 6.8 0.2 3.6 4 0 0 4 4 4 0 UME (NUC010) domain Snurportin1 PF11538.8 RUS89826.1 - 1.4e-05 25.2 1.0 2.9e-05 24.2 1.0 1.4 1 0 0 1 1 1 1 Snurportin1 mRNA_cap_enzyme PF01331.19 RUS89826.1 - 0.0001 22.2 0.0 0.00028 20.7 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain zf-MIZ PF02891.20 RUS89827.1 - 0.024 14.4 0.6 0.045 13.5 0.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RVT_1 PF00078.27 RUS89829.1 - 8.4e-07 28.7 0.1 2.9e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.16 RUS89830.1 - 1e-24 86.4 0.0 3.8e-13 49.3 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS89830.1 - 2.3e-23 82.6 0.0 6.8e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS89830.1 - 1.4e-16 60.4 0.1 8.5e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS89830.1 - 1.7e-14 53.9 0.3 2.4e-08 34.1 0.0 3.8 3 2 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS89830.1 - 6.6e-14 52.0 0.0 1.6e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS89830.1 - 2e-05 24.1 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 RUS89830.1 - 7.6e-05 22.7 0.1 0.22 11.6 0.0 2.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS89830.1 - 0.00012 22.3 0.1 5.4 7.3 0.0 4.2 2 2 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS89830.1 - 0.00081 19.8 0.2 1.6 9.2 0.1 3.6 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 RUS89830.1 - 0.00093 19.5 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.11 RUS89830.1 - 0.008 16.2 0.2 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 RUS89830.1 - 0.11 12.6 0.2 0.62 10.2 0.0 2.3 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain SLATT_4 PF18186.1 RUS89831.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Ependymin PF00811.18 RUS89832.1 - 6.4e-11 42.6 0.1 9.8e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Ependymin THUMP PF02926.17 RUS89833.1 - 1.9e-05 24.8 0.0 5.5e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 THUMP domain fn3 PF00041.21 RUS89834.1 - 3.2e-53 178.0 20.2 4.9e-09 36.4 0.1 7.6 7 0 0 7 7 7 7 Fibronectin type III domain DB PF01682.19 RUS89834.1 - 1.4e-50 169.7 87.1 2.3e-14 53.5 9.7 5.7 5 0 0 5 5 5 5 DB module I-set PF07679.16 RUS89834.1 - 3.6e-23 81.4 0.4 1.9e-08 34.2 0.0 4.4 4 1 0 4 4 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS89834.1 - 1.6e-21 76.6 0.3 2.3e-05 24.9 0.0 4.4 4 0 0 4 4 3 3 Immunoglobulin domain V-set PF07686.17 RUS89834.1 - 2.6e-15 56.5 7.3 1.3e-06 28.6 0.1 6.2 5 1 1 6 6 6 3 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS89834.1 - 1.4e-09 38.1 0.2 0.0017 18.7 0.0 4.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS89834.1 - 5.1e-08 33.0 8.4 0.0034 17.5 0.1 4.4 4 1 0 4 4 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS89834.1 - 1e-06 29.2 16.6 0.48 11.0 0.0 6.7 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain V-set_CD47 PF08204.11 RUS89834.1 - 8.3e-06 25.8 0.5 1.1 9.3 0.1 4.2 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Interfer-bind PF09294.10 RUS89834.1 - 7e-05 23.1 7.4 4.7 7.6 0.0 6.2 5 1 1 6 6 6 1 Interferon-alpha/beta receptor, fibronectin type III SKG6 PF08693.10 RUS89834.1 - 0.00013 21.3 0.8 0.00038 19.8 0.8 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4998 PF16389.5 RUS89834.1 - 0.001 18.7 1.5 2.2 7.8 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function C1-set PF07654.15 RUS89834.1 - 0.018 15.4 0.4 26 5.3 0.0 4.4 3 2 1 4 4 4 0 Immunoglobulin C1-set domain DUF2207 PF09972.9 RUS89834.1 - 0.024 13.4 0.3 0.043 12.6 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Izumo-Ig PF16706.5 RUS89834.1 - 0.068 13.2 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Tissue_fac PF01108.17 RUS89834.1 - 2.1 8.2 12.6 0.37 10.6 0.2 4.6 5 1 1 6 6 5 0 Tissue factor AAA PF00004.29 RUS89835.1 - 1.1e-12 48.5 1.2 2.3e-12 47.5 0.0 2.2 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS89835.1 - 6.7e-09 35.9 0.0 1.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 RUS89835.1 - 1.3e-07 31.8 0.2 4.1e-06 26.9 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain RFC1 PF08519.12 RUS89835.1 - 9.1e-07 29.2 0.2 3.4e-06 27.3 0.2 2.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain RuvB_N PF05496.12 RUS89835.1 - 2e-06 27.6 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RUS89835.1 - 6.8e-06 26.4 0.0 9.2e-05 22.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RUS89835.1 - 7.6e-05 22.8 0.0 0.00027 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS89835.1 - 0.00012 22.3 0.0 0.00054 20.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 RUS89835.1 - 0.00031 21.2 0.2 0.0023 18.3 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RUS89835.1 - 0.0004 20.9 0.0 0.0024 18.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 RUS89835.1 - 0.0017 17.6 0.0 0.0055 15.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 RUS89835.1 - 0.0018 17.9 0.0 0.0055 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_8 PF12780.7 RUS89835.1 - 0.0075 15.6 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_17 PF13207.6 RUS89835.1 - 0.0079 16.6 0.1 0.14 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS89835.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RUS89835.1 - 0.021 15.1 0.0 0.089 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 RUS89835.1 - 0.022 14.0 0.0 0.064 12.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RUS89835.1 - 0.039 14.5 0.7 0.39 11.2 0.1 2.9 2 1 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 RUS89835.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RUS89835.1 - 0.055 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 RUS89835.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RUS89835.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 RUS89835.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 RUS89835.1 - 0.21 10.9 0.8 3.8 6.8 0.0 2.9 3 0 0 3 3 3 0 KaiC HlyIII PF03006.20 RUS89836.1 - 1.3e-19 70.8 22.9 1.9e-19 70.3 22.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related MAPEG PF01124.18 RUS89836.1 - 0.033 14.1 7.5 0.075 12.9 0.5 2.6 1 1 1 2 2 2 0 MAPEG family DUF3593 PF12159.8 RUS89836.1 - 0.054 13.5 1.6 0.054 13.5 1.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) RRM_1 PF00076.22 RUS89837.1 - 1.1e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stork_head PF10264.9 RUS89839.1 - 6.7e-23 80.7 0.0 1.3e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain FYRN PF05964.14 RUS89839.1 - 0.19 11.6 0.3 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 F/Y-rich N-terminus GIY-YIG PF01541.24 RUS89840.1 - 3.2e-14 53.0 0.0 5.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 RUS89840.1 - 0.01 16.0 4.0 0.024 14.8 4.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 RUS89840.1 - 0.023 15.0 3.2 0.042 14.1 3.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain T5orf172 PF10544.9 RUS89840.1 - 0.032 14.7 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain zf-HC5HC2H_2 PF13832.6 RUS89840.1 - 0.065 13.4 3.3 0.13 12.5 3.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 RUS89840.1 - 0.088 13.1 4.0 0.21 11.9 4.0 1.7 1 0 0 1 1 1 0 RING-like domain MUG113 PF13455.6 RUS89840.1 - 0.15 12.8 0.1 0.38 11.4 0.0 1.7 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 PHD PF00628.29 RUS89840.1 - 1.2 9.1 7.2 2.5 8.1 7.2 1.6 1 0 0 1 1 1 0 PHD-finger CSN4_RPN5_eIF3a PF18420.1 RUS89841.1 - 2e-21 75.8 0.8 5.5e-21 74.5 0.8 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 RUS89841.1 - 1.4e-16 60.9 0.5 4.2e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 RUS89841.1 - 0.00061 19.6 2.5 0.00097 18.9 2.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TCR PF03638.15 RUS89842.1 - 1.2e-23 83.1 55.8 3.7e-12 46.3 23.5 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 RUS89842.1 - 0.026 14.6 44.3 0.3 11.3 17.8 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 GTP_CH_N PF12471.8 RUS89842.1 - 0.093 12.5 0.6 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal DUF4805 PF16063.5 RUS89842.1 - 1.1 8.6 9.8 0.031 13.6 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) G-alpha PF00503.20 RUS89843.1 - 2.4e-100 336.1 0.1 2.8e-100 335.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS89843.1 - 4.8e-12 45.7 0.9 1.9e-09 37.2 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS89843.1 - 0.0045 16.5 0.1 1 8.9 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 RUS89843.1 - 0.011 16.0 0.0 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2985 PF11204.8 RUS89843.1 - 0.034 14.3 0.2 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) TssR PF17643.1 RUS89845.1 - 0.00073 17.6 13.5 0.044 11.7 4.2 2.3 1 1 1 2 2 2 2 Type VI secretion system, TssR DUF745 PF05335.13 RUS89845.1 - 0.059 13.1 0.2 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DASH_Spc19 PF08287.11 RUS89845.1 - 1.1 9.2 10.4 6.7 6.6 1.4 3.1 1 1 2 3 3 3 0 Spc19 DUF3116 PF11313.8 RUS89845.1 - 2 8.3 10.3 27 4.7 1.5 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) RnlB_antitoxin PF15933.5 RUS89845.1 - 6.2 7.2 15.6 1.2e+02 3.1 4.6 3.1 1 1 1 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA DUF4164 PF13747.6 RUS89846.1 - 2.8e-05 24.3 6.8 0.00011 22.4 2.7 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 RUS89846.1 - 0.00014 21.9 1.3 0.085 12.9 0.1 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RUS89846.1 - 0.0024 17.8 9.2 0.005 16.7 9.2 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Vps52 PF04129.12 RUS89846.1 - 0.0032 16.3 0.6 0.0047 15.7 0.6 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Curto_V3 PF07436.11 RUS89846.1 - 0.074 13.4 0.8 2.1 8.8 0.0 2.6 1 1 1 2 2 2 0 Curtovirus V3 protein Exonuc_VII_L PF02601.15 RUS89846.1 - 0.11 12.1 4.7 0.16 11.5 4.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.11 RUS89846.1 - 0.24 11.4 6.6 0.063 13.3 1.8 2.3 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 RUS89846.1 - 0.28 11.2 7.0 2.5 8.1 1.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 RUS89846.1 - 0.37 10.6 4.3 0.55 10.0 1.2 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 RUS89846.1 - 0.67 10.5 3.6 11 6.6 0.3 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 RUS89846.1 - 0.75 10.1 3.4 3 8.2 0.2 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 RUS89846.1 - 1.4 8.5 12.2 4.1 6.9 8.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TolA_bind_tri PF16331.5 RUS89846.1 - 2.8 8.1 7.6 6.4 6.9 1.1 3.7 2 1 1 3 3 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 RUS89846.1 - 3.4 6.9 7.0 6.6 6.0 7.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BST2 PF16716.5 RUS89846.1 - 4.7 7.9 8.1 1.5 9.4 1.5 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Fibrinogen_C PF00147.18 RUS89847.1 - 3.2e-72 242.9 20.3 1.5e-54 185.1 8.5 2.1 1 1 1 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain EF-hand_1 PF00036.32 RUS89847.1 - 0.12 12.0 2.2 13 5.6 0.2 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 RUS89847.1 - 2.6 8.2 4.3 41 4.5 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain 7tm_1 PF00001.21 RUS89848.1 - 4.5e-35 121.3 0.8 4.5e-35 121.3 0.8 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) UPF0029 PF01205.19 RUS89850.1 - 6.9e-34 116.3 0.0 1.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 RUS89850.1 - 0.0031 17.8 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 RWD domain zf-H2C2_5 PF13909.6 RUS89851.1 - 2.6e-25 87.8 185.0 0.0002 21.1 0.4 21.9 22 0 0 22 22 22 13 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS89851.1 - 0.00022 21.5 12.6 0.0027 18.1 0.6 25.5 30 0 0 30 30 30 6 Zinc-finger double domain zf_ZIC PF18366.1 RUS89851.1 - 0.004 17.2 0.2 0.004 17.2 0.2 3.5 4 0 0 4 4 4 1 Zic proteins zinc finger domain vATP-synt_E PF01991.18 RUS89851.1 - 0.037 13.4 1.2 0.12 11.8 1.2 1.8 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-C2H2 PF00096.26 RUS89851.1 - 0.3 11.6 207.4 0.13 12.8 0.3 25.9 26 0 0 26 26 26 0 Zinc finger, C2H2 type Cation_efflux PF01545.21 RUS89852.1 - 0.014 15.1 15.6 0.4 10.4 15.2 2.8 1 1 0 1 1 1 0 Cation efflux family DUF3648 PF12364.8 RUS89852.1 - 0.046 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) 7TM_GPCR_Sri PF10327.9 RUS89852.1 - 1.7 7.7 8.1 0.049 12.8 0.9 2.0 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Sri Vps51 PF08700.11 RUS89853.1 - 3.1e-26 91.3 4.4 5.2e-26 90.5 2.3 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 RUS89853.1 - 1.6e-20 73.8 7.8 4.5e-20 72.3 4.9 2.7 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 RUS89853.1 - 6e-13 48.2 4.3 6e-13 48.2 4.3 1.9 2 1 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 RUS89853.1 - 2.8e-08 33.4 7.8 7.7e-08 32.0 7.8 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 RUS89853.1 - 1.4e-06 28.4 0.9 1.4e-06 28.4 0.9 4.4 5 1 0 5 5 4 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 RUS89853.1 - 0.00062 19.9 1.4 0.00062 19.9 1.4 4.0 4 1 0 4 4 4 1 Golgi transport complex subunit 5 Vps53_N PF04100.12 RUS89853.1 - 0.0037 16.3 8.0 0.01 14.8 8.0 1.8 1 0 0 1 1 1 1 Vps53-like, N-terminal Occludin_ELL PF07303.13 RUS89853.1 - 0.059 14.1 3.8 0.14 12.9 0.1 3.1 1 1 2 3 3 3 0 Occludin homology domain DASH_Dam1 PF08653.10 RUS89853.1 - 0.19 11.6 1.8 0.99 9.3 0.2 3.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Apolipoprotein PF01442.18 RUS89853.1 - 0.24 11.3 9.4 1.3 8.9 0.3 3.6 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 RUS89853.1 - 0.99 10.0 2.6 7.9 7.1 0.0 3.2 3 0 0 3 3 3 0 YtxH-like protein Sec8_exocyst PF04048.14 RUS89853.1 - 1.2 9.0 5.5 0.2 11.6 0.7 2.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain UPF0449 PF15136.6 RUS89853.1 - 2.6 8.6 6.0 8.1 7.0 0.6 3.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 GIT_CC PF16559.5 RUS89853.1 - 4.6 7.2 7.5 3.2 7.7 0.4 3.6 4 0 0 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ASC PF00858.24 RUS89854.1 - 2.6e-84 283.7 23.3 7.7e-83 278.9 23.3 2.2 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Ldl_recept_a PF00057.18 RUS89854.1 - 1.6e-12 47.4 36.3 8.5e-08 32.3 14.2 3.0 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Flavodoxin_4 PF12682.7 RUS89854.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin NfI_DNAbd_pre-N PF10524.9 RUS89856.1 - 9.1e-25 86.3 4.2 1.8e-24 85.3 4.2 1.5 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 RUS89856.1 - 4.6e-12 46.1 1.2 8.7e-12 45.2 1.2 1.5 1 0 0 1 1 1 1 MH1 domain Speriolin_N PF15058.6 RUS89859.1 - 0.13 12.3 9.9 68 3.5 9.9 3.2 1 1 0 1 1 1 0 Speriolin N terminus Spore-coat_CotD PF11122.8 RUS89859.1 - 0.17 12.7 0.1 17 6.3 0.1 3.4 1 1 0 1 1 1 0 Inner spore coat protein D MSSP PF03940.13 RUS89859.1 - 0.17 11.5 6.2 8.5 6.1 1.2 4.2 1 1 0 2 2 2 0 Male specific sperm protein DUF445 PF04286.12 RUS89860.1 - 0.073 12.9 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Porphobil_deam PF01379.20 RUS89860.1 - 0.15 11.5 5.8 4.2 6.8 0.4 2.7 1 1 1 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Glyco_transf_7N PF13733.6 RUS89861.1 - 6.1e-50 168.3 0.0 8.2e-50 167.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS89861.1 - 1e-17 63.5 0.8 1.9e-17 62.7 0.8 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CENP-B_dimeris PF09026.10 RUS89862.1 - 2.6e-05 24.5 15.0 5e-05 23.6 15.0 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Pex24p PF06398.11 RUS89862.1 - 0.0013 17.8 0.0 0.01 14.9 0.0 1.9 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin DUF1676 PF07898.13 RUS89862.1 - 0.0019 18.2 0.8 0.0019 18.2 0.8 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF1676) DNA_pol_phi PF04931.13 RUS89862.1 - 0.0023 16.2 14.9 0.003 15.8 14.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi SARAF PF06682.12 RUS89862.1 - 0.016 14.9 5.5 2.6 7.6 4.2 2.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 RUS89862.1 - 0.018 15.3 0.0 0.018 15.3 0.0 3.3 2 1 0 2 2 1 0 Orf78 (ac78) RRN3 PF05327.11 RUS89862.1 - 0.027 13.0 6.6 0.036 12.6 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 RUS89862.1 - 0.034 13.7 5.9 0.055 13.1 5.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BUD22 PF09073.10 RUS89862.1 - 0.055 12.8 2.5 0.068 12.5 2.5 1.1 1 0 0 1 1 1 0 BUD22 SUR7 PF06687.12 RUS89862.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 SUR7/PalI family Utp14 PF04615.13 RUS89862.1 - 0.31 9.6 5.7 0.37 9.3 5.7 1.1 1 0 0 1 1 1 0 Utp14 protein DHHC PF01529.20 RUS89862.1 - 0.56 10.3 0.1 0.56 10.3 0.1 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF5383 PF17355.2 RUS89862.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.2 2 1 0 2 2 1 0 Family of unknown function (DUF5383) DUF898 PF05987.13 RUS89862.1 - 1.4 7.9 15.1 8.3 5.3 5.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) NOA36 PF06524.12 RUS89862.1 - 1.4 8.1 26.0 2 7.7 26.0 1.1 1 0 0 1 1 1 0 NOA36 protein VWD PF00094.25 RUS89863.1 - 4.7e-27 95.2 0.2 8.9e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain DUF3011 PF11218.8 RUS89863.1 - 1.7e-16 60.8 2.2 1.1e-07 32.1 0.3 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3011) C8 PF08742.11 RUS89863.1 - 1.3e-13 51.1 5.9 1.3e-13 51.1 5.9 3.3 3 0 0 3 3 3 1 C8 domain TIL PF01826.17 RUS89863.1 - 2.4e-10 40.5 11.2 2.4e-10 40.5 11.2 4.2 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 RUS89863.1 - 7.7e-06 26.0 4.9 7.7e-06 26.0 4.9 4.0 3 1 1 4 4 4 1 EGF domain EGF_MSP1_1 PF12946.7 RUS89863.1 - 0.014 15.5 4.8 0.014 15.5 4.8 3.6 3 0 0 3 3 3 0 MSP1 EGF domain 1 VWD PF00094.25 RUS89864.1 - 1.4e-18 67.6 0.1 2.2e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 RUS89864.1 - 5.3e-11 42.8 1.8 5.3e-11 42.8 1.8 2.7 3 0 0 3 3 3 1 C8 domain TIL PF01826.17 RUS89864.1 - 2.8e-08 33.9 8.2 2.8e-08 33.9 8.2 3.5 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain EGF_MSP1_1 PF12946.7 RUS89864.1 - 0.00045 20.2 10.0 0.00055 19.9 1.5 3.4 3 0 0 3 3 3 1 MSP1 EGF domain 1 TILa PF12714.7 RUS89864.1 - 6.7 6.8 13.3 0.041 13.8 2.5 3.0 2 1 0 2 2 2 0 TILa domain VWD PF00094.25 RUS89865.1 - 3.9e-16 59.7 0.4 5.3e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type D domain DUF4793 PF16041.5 RUS89865.1 - 0.18 12.0 0.1 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) Glyco_transf_10 PF00852.19 RUS89866.1 - 3.5e-38 131.1 0.1 4e-38 130.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term zf-CCCH_6 PF18585.1 RUS89866.1 - 0.23 11.4 1.4 0.43 10.5 0.1 2.1 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 VWA PF00092.28 RUS89867.1 - 1.7e-114 380.1 12.7 2.8e-42 144.9 3.3 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 RUS89867.1 - 1.9e-34 118.5 3.5 7e-12 45.9 0.1 4.1 4 0 0 4 4 4 3 von Willebrand factor type A domain Apolipoprotein PF01442.18 RUS89867.1 - 5.1e-13 49.3 0.0 3.4e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain VWA_3 PF13768.6 RUS89867.1 - 7.6e-12 45.4 0.0 2e-05 24.6 0.0 3.5 3 0 0 3 3 3 2 von Willebrand factor type A domain Baculo_PEP_C PF04513.12 RUS89867.1 - 3.1e-05 24.1 36.0 0.49 10.4 9.8 4.1 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus ShK PF01549.24 RUS89867.1 - 3.6e-05 24.2 57.0 0.0012 19.4 9.5 5.2 5 0 0 5 5 5 3 ShK domain-like Ig_3 PF13927.6 RUS89867.1 - 0.00032 21.2 5.4 0.075 13.6 0.3 3.8 3 0 0 3 3 3 1 Immunoglobulin domain VWC PF00093.18 RUS89867.1 - 0.0019 18.4 13.2 0.0019 18.4 13.2 5.7 6 0 0 6 6 6 3 von Willebrand factor type C domain EST1 PF10374.9 RUS89867.1 - 0.015 16.0 18.1 2.6 8.7 0.4 4.5 1 1 1 2 2 2 0 Telomerase activating protein Est1 Phasin PF05597.11 RUS89867.1 - 0.049 13.6 10.6 29 4.7 0.3 4.3 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Rab5ip PF07019.12 RUS89868.1 - 0.028 15.0 9.8 41 4.9 0.3 4.7 1 1 2 3 3 3 0 Rab5-interacting protein (Rab5ip) Lectin_C PF00059.21 RUS89869.1 - 4.6e-09 37.0 0.0 6.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain TnpB_IS66 PF05717.13 RUS89869.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.5 1 1 0 1 1 1 0 IS66 Orf2 like protein Pentapeptide_4 PF13599.6 RUS89870.1 - 8.3e-48 160.5 36.5 6.3e-12 45.5 1.3 5.3 2 1 5 7 7 7 7 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 RUS89870.1 - 3.2e-26 91.2 56.0 6e-05 23.1 2.7 8.6 2 2 4 6 6 6 6 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 RUS89870.1 - 2e-20 72.0 0.5 0.00073 19.1 0.0 8.2 3 2 5 9 9 9 8 Pentapeptide repeats (8 copies) Lectin_C PF00059.21 RUS89871.1 - 9.7e-09 35.9 0.0 1.4e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain VWA PF00092.28 RUS89872.1 - 6.9e-09 36.2 0.0 9.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 RUS89872.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_A25 PF03418.14 RUS89872.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Germination protease Msg2_C PF12373.8 RUS89874.1 - 0.4 10.1 2.2 8.6 5.9 0.1 2.3 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal ig PF00047.25 RUS89875.1 - 0.042 14.0 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Lectin_C PF00059.21 RUS89876.1 - 4.5e-07 30.6 0.0 6.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain MFS_1 PF07690.16 RUS89877.1 - 2e-13 50.0 6.0 6.5e-11 41.7 0.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_memb PF02932.16 RUS89878.1 - 4.1e-26 92.5 9.6 3e-25 89.7 5.1 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_2 PF12679.7 RUS89878.1 - 9.5e-05 21.8 3.9 0.0011 18.3 4.6 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF2417 PF10329.9 RUS89878.1 - 0.027 13.9 3.2 0.043 13.2 3.2 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) YrhC PF14143.6 RUS89878.1 - 0.035 14.2 3.4 0.035 14.2 3.4 2.0 2 0 0 2 2 2 0 YrhC-like protein Neur_chan_LBD PF02931.23 RUS89878.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain 8TM_micro PF17028.5 RUS89878.1 - 0.73 9.5 7.2 1.4 8.6 7.2 1.5 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Tetraspanin PF00335.20 RUS89878.1 - 1.3 8.7 7.9 0.2 11.3 3.4 1.9 2 1 0 2 2 2 0 Tetraspanin family Neur_chan_LBD PF02931.23 RUS89879.1 - 9.7e-58 195.1 7.1 4.9e-39 134.0 0.7 3.1 3 0 0 3 3 3 3 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS89879.1 - 8.2e-17 62.1 16.4 1.7e-12 47.9 2.4 10.2 3 1 6 9 9 9 6 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 RUS89880.1 - 7.2e-36 123.7 0.0 1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS89880.1 - 2.9e-24 86.4 7.3 1.4e-23 84.2 3.9 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 RUS89880.1 - 0.022 14.2 1.4 0.045 13.2 1.4 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Tetraspanin PF00335.20 RUS89880.1 - 0.078 12.7 1.3 0.22 11.2 1.3 1.8 1 0 0 1 1 1 0 Tetraspanin family YrhC PF14143.6 RUS89880.1 - 1.1 9.4 8.8 0.072 13.2 3.4 1.9 2 0 0 2 2 2 0 YrhC-like protein Peptidase_C27 PF05407.12 RUS89881.1 - 0.025 14.7 0.0 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Rubella virus endopeptidase p450 PF00067.22 RUS89882.1 - 0.0096 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDO_I PF05995.12 RUS89882.1 - 0.15 11.4 8.1 0.25 10.7 2.1 2.2 2 0 0 2 2 2 0 Cysteine dioxygenase type I ecTbetaR2 PF08917.10 RUS89883.1 - 0.1 12.5 0.0 2.1e+02 1.9 0.0 3.9 1 1 5 7 7 7 0 Transforming growth factor beta receptor 2 ectodomain FATC PF02260.20 RUS89883.1 - 0.57 10.1 18.2 1.6e+02 2.2 0.0 8.0 10 0 0 10 10 10 0 FATC domain PAX PF00292.18 RUS89885.1 - 8.1e-66 219.6 1.3 1.7e-65 218.6 0.3 2.0 1 1 1 2 2 2 1 'Paired box' domain Homeodomain PF00046.29 RUS89885.1 - 5.9e-22 77.3 3.0 1.2e-21 76.2 3.0 1.6 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 RUS89885.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 RUS89885.1 - 0.0098 16.5 0.3 13 6.5 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 RUS89885.1 - 0.014 15.0 0.0 0.056 13.1 0.0 2.0 2 0 0 2 2 2 0 InsA C-terminal domain Homeobox_KN PF05920.11 RUS89885.1 - 0.047 13.6 0.6 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 Homeobox KN domain SDA1 PF05285.12 RUS89886.1 - 0.00045 19.8 13.5 0.0005 19.6 13.5 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 RUS89886.1 - 0.00062 18.2 8.3 0.00062 18.2 8.3 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 RUS89886.1 - 0.11 11.9 14.1 0.11 11.8 14.1 1.2 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.12 RUS89886.1 - 0.45 8.8 4.9 0.46 8.7 4.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RUS89886.1 - 0.48 8.6 23.7 0.6 8.3 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.9 RUS89886.1 - 0.88 8.5 7.9 1.2 8.0 7.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DNA_pol_phi PF04931.13 RUS89886.1 - 2.5 6.1 39.9 3.3 5.7 39.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 RUS89886.1 - 3.8 5.9 16.6 4.7 5.5 16.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Ank_2 PF12796.7 RUS89888.1 - 3.9e-35 120.3 2.6 2.8e-13 50.2 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS89888.1 - 5.7e-30 103.0 11.3 5.9e-08 32.8 0.1 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS89888.1 - 4.8e-29 97.2 6.9 0.00011 22.4 0.1 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 RUS89888.1 - 3.6e-28 96.8 22.1 4.2e-06 26.9 0.6 7.4 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 RUS89888.1 - 1.8e-26 92.1 13.1 4.9e-06 27.0 0.1 6.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) YhhN PF07947.14 RUS89889.1 - 1.3e-38 132.5 18.7 1.8e-38 132.0 18.7 1.2 1 0 0 1 1 1 1 YhhN family MerC PF03203.14 RUS89889.1 - 0.6 10.6 11.0 1.7 9.2 10.0 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein Tetraspanin PF00335.20 RUS89890.1 - 1.5e-13 51.0 0.1 2.2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family MADF_DNA_bdg PF10545.9 RUS89891.1 - 1.3e-17 63.9 1.2 3.8e-16 59.2 0.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS89891.1 - 4.7e-05 23.1 0.2 9.4e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 BESS motif Med25 PF11232.8 RUS89892.1 - 6e-07 29.6 0.2 6e-07 29.6 0.2 3.2 2 2 2 4 4 4 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Phage_GPO PF05929.11 RUS89892.1 - 0.93 9.1 17.6 0.2 11.3 3.4 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ATG22 PF11700.8 RUS89892.1 - 1 7.9 3.1 1.8 7.1 3.1 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like LMBR1 PF04791.16 RUS89892.1 - 1.6 7.6 5.5 2 7.2 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GIDA_assoc PF13932.6 RUS89892.1 - 2.5 8.2 13.5 1.6 8.9 2.5 2.3 2 0 0 2 2 2 0 GidA associated domain FKBP_N PF01346.18 RUS89892.1 - 3.7 8.6 39.7 0.48 11.4 10.2 2.9 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ndc1_Nup PF09531.10 RUS89892.1 - 3.7 6.1 19.7 5.5 5.5 19.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FHIPEP PF00771.20 RUS89892.1 - 5.2 5.4 13.7 0.11 10.9 1.9 2.1 2 0 0 2 2 2 0 FHIPEP family Med25_VWA PF11265.8 RUS89893.1 - 7.2e-81 271.1 0.0 1.1e-80 270.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med25 PF11232.8 RUS89893.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 TFIIA PF03153.13 RUS89893.1 - 0.23 11.4 34.6 0.4 10.6 34.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FARP PF01581.16 RUS89895.1 - 0.0031 17.7 28.1 1.8e+02 3.4 0.1 15.3 18 1 1 19 19 19 0 FMRFamide related peptide family S1 PF00575.23 RUS89895.1 - 0.1 12.9 0.1 13 6.2 0.0 3.1 2 0 0 2 2 2 0 S1 RNA binding domain Clr2 PF10383.9 RUS89895.1 - 0.14 13.0 0.0 0.32 11.8 0.0 1.7 1 1 1 2 2 2 0 Transcription-silencing protein Clr2 RNA_pol_Rpb5_C PF01191.19 RUS89896.1 - 0.0099 15.7 22.7 4.5 7.2 0.9 7.0 1 1 5 6 6 6 4 RNA polymerase Rpb5, C-terminal domain IF3_N PF05198.16 RUS89896.1 - 0.026 14.8 8.4 1.1 9.6 1.5 2.8 1 1 1 2 2 2 0 Translation initiation factor IF-3, N-terminal domain DUF1449 PF07290.11 RUS89896.1 - 0.18 11.4 7.0 13 5.3 0.2 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1449) DivIVA PF05103.13 RUS89896.1 - 0.21 11.7 17.7 3.9 7.6 6.5 2.3 1 1 1 2 2 2 0 DivIVA protein DAP_B PF07930.12 RUS89896.1 - 1.5 8.7 10.4 7.8 6.4 10.4 1.9 1 1 0 1 1 1 0 D-aminopeptidase, domain B Thymidylat_synt PF00303.19 RUS89897.1 - 1.7e-111 371.6 0.0 2.3e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase Pkinase PF00069.25 RUS89898.1 - 4.7e-23 81.9 0.0 7.6e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89898.1 - 3.4e-15 56.0 0.0 5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS89898.1 - 0.0055 16.1 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF719 PF05334.13 RUS89898.1 - 0.034 14.4 3.6 0.075 13.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Rtf2 PF04641.12 RUS89898.1 - 0.18 11.2 12.3 0.2 11.0 1.5 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger NKAP PF15692.5 RUS89899.1 - 6.5e-15 55.6 21.8 6.5e-15 55.6 21.8 3.7 2 1 1 3 3 3 1 NF-kappa-B-activating protein UQ_con PF00179.26 RUS89902.1 - 7.3e-39 132.6 0.0 1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RUS89902.1 - 0.0054 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 RUS89902.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B FAM221 PF14753.6 RUS89903.1 - 2.6e-91 304.6 8.4 3.4e-91 304.2 8.4 1.1 1 0 0 1 1 1 1 Protein FAM221A/B GPW_gp25 PF04965.14 RUS89904.1 - 0.083 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Gene 25-like lysozyme Glyco_hydro_18 PF00704.28 RUS89906.1 - 0.053 13.2 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 DNA_methylase PF00145.17 RUS89907.1 - 1.3e-41 143.0 0.0 3.1e-41 141.8 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cation_efflux PF01545.21 RUS89908.1 - 3.8e-55 186.7 6.2 5.3e-55 186.2 6.2 1.2 1 0 0 1 1 1 1 Cation efflux family FAM176 PF14851.6 RUS89908.1 - 0.046 13.4 0.3 2.9 7.5 0.6 2.7 3 0 0 3 3 3 0 FAM176 family BTB PF00651.31 RUS89909.1 - 2.8e-18 66.2 0.3 2.8e-18 66.2 0.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain Tetraspanin PF00335.20 RUS89910.1 - 1.2e-54 185.5 10.0 1.4e-54 185.2 10.0 1.0 1 0 0 1 1 1 1 Tetraspanin family GAD-like PF08887.11 RUS89910.1 - 0.0081 15.9 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 GAD-like domain DUF4064 PF13273.6 RUS89910.1 - 0.036 14.3 4.1 1.2 9.5 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) F-box_4 PF15966.5 RUS89911.1 - 3.6e-35 120.3 0.3 3.6e-35 120.3 0.3 2.3 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 RUS89911.1 - 4.4e-29 100.8 24.1 4.4e-29 100.8 24.1 2.7 3 1 1 4 4 4 1 TRAF-like zinc-finger F-box PF00646.33 RUS89911.1 - 4.9e-08 32.7 1.3 1.9e-07 30.8 1.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 RUS89911.1 - 1.2e-05 25.1 1.6 3e-05 23.8 1.6 1.7 1 0 0 1 1 1 1 F-box-like zf-U11-48K PF05253.12 RUS89911.1 - 0.035 14.0 0.6 3.9 7.5 0.3 3.1 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger zf-H2C2_2 PF13465.6 RUS89912.1 - 4.3e-30 102.8 45.2 1.4e-06 28.5 0.7 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 RUS89912.1 - 1.7e-24 84.8 49.2 0.00013 22.2 0.3 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS89912.1 - 7.1e-13 48.2 46.8 0.0058 17.4 0.2 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RUS89912.1 - 0.00013 22.2 14.2 0.12 12.7 5.6 3.5 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 RUS89912.1 - 0.00026 21.2 23.7 0.13 12.4 0.2 5.1 2 2 2 4 4 4 3 Aberrant zinc-finger zf-TRAF PF02176.18 RUS89912.1 - 0.1 13.3 15.4 0.21 12.3 0.2 3.9 2 1 2 4 4 4 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 RUS89912.1 - 0.14 12.2 0.1 0.14 12.2 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS89912.1 - 0.36 11.2 16.6 1.3 9.4 0.2 5.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding BST2 PF16716.5 RUS89912.1 - 1.9 9.1 10.9 0.93 10.1 6.6 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SPRY PF00622.28 RUS89914.1 - 4.3e-23 81.7 0.0 5.2e-10 39.5 0.0 3.3 3 0 0 3 3 3 3 SPRY domain Jag_N PF14804.6 RUS89914.1 - 0.15 12.5 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Jag N-terminus Cnn_1N PF07989.11 RUS89915.1 - 0.012 15.8 6.0 0.012 15.8 6.0 6.8 3 1 3 6 6 6 0 Centrosomin N-terminal motif 1 YabA PF06156.13 RUS89915.1 - 0.022 15.4 57.0 1.9 9.2 0.3 6.7 1 1 3 5 5 5 0 Initiation control protein YabA DivIC PF04977.15 RUS89915.1 - 0.51 10.2 58.4 0.52 10.1 5.3 7.5 4 3 3 7 7 7 0 Septum formation initiator ZapB PF06005.12 RUS89915.1 - 1 9.8 76.7 1.1 9.8 0.1 7.2 4 3 3 7 7 7 0 Cell division protein ZapB HrpB7 PF09486.10 RUS89915.1 - 3.2 8.1 45.4 0.019 15.4 17.7 5.0 1 1 4 5 5 5 0 Bacterial type III secretion protein (HrpB7) HAP1_N PF04849.13 RUS89915.1 - 6.7 5.8 69.1 0.0097 15.1 31.2 4.4 1 1 1 3 3 3 0 HAP1 N-terminal conserved region Atg14 PF10186.9 RUS89915.1 - 8.4 5.4 60.0 1.4e+02 1.3 2.7 4.2 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 T2SSF PF00482.23 RUS89915.1 - 9.9 6.1 7.6 2.3 8.2 2.1 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F vWA-TerF-like PF10138.9 RUS89916.1 - 0.18 11.9 0.0 24 4.9 0.0 3.4 2 1 0 3 3 3 0 vWA found in TerF C terminus 7tm_1 PF00001.21 RUS89918.1 - 0.0098 15.2 6.3 0.027 13.8 3.3 2.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4220 PF13968.6 RUS89918.1 - 0.9 8.9 7.3 0.037 13.4 1.1 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4220) Sina PF03145.16 RUS89919.1 - 1.2e-82 276.7 0.0 1.7e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Prok-RING_4 PF14447.6 RUS89919.1 - 1.9 8.4 13.5 34 4.4 12.8 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS89919.1 - 5.4 7.2 15.2 0.25 11.6 8.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Lectin_C PF00059.21 RUS89920.1 - 4.9e-10 40.1 0.3 7.1e-10 39.6 0.0 1.4 2 0 0 2 2 2 1 Lectin C-type domain Prok-RING_2 PF14445.6 RUS89920.1 - 0.016 15.3 0.7 0.025 14.7 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 PAN_1 PF00024.26 RUS89921.1 - 0.0071 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 PAN domain Fibrinogen_C PF00147.18 RUS89923.1 - 3.3e-26 92.5 2.1 3.9e-26 92.2 2.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Piwi PF02171.17 RUS89924.1 - 1.9e-85 286.8 0.0 2.9e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RUS89924.1 - 1.2e-30 106.2 0.1 9.5e-30 103.2 0.4 2.3 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.10 RUS89924.1 - 0.0042 16.7 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain TFIIA PF03153.13 RUS89924.1 - 8.2 6.3 9.9 14 5.5 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0561 PF10573.9 RUS89925.1 - 7.7e-17 61.5 5.9 1.6e-13 50.8 3.9 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0561 Virulence_fact PF13769.6 RUS89925.1 - 0.011 15.9 1.3 0.17 12.1 0.4 2.1 2 0 0 2 2 2 0 Virulence factor Coilin_N PF15862.5 RUS89925.1 - 0.23 11.2 5.2 9.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Coilin N-terminus DDE_Tnp_4 PF13359.6 RUS89926.1 - 1e-18 67.5 0.0 2e-17 63.3 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS89926.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein CarbopepD_reg_2 PF13715.6 RUS89926.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 RUS89926.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.7 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RA PF00788.23 RUS89928.1 - 2.3e-13 50.6 0.0 3e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 RUS89928.1 - 5.4e-13 49.1 0.2 1.5e-12 47.7 0.2 1.9 1 0 0 1 1 1 1 DIL domain PDZ PF00595.24 RUS89928.1 - 6.1e-12 45.7 0.0 7.5e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 RUS89928.1 - 9.1e-10 38.2 0.3 2.2e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS89928.1 - 0.00016 22.0 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF3677 PF12432.8 RUS89929.1 - 3.5e-31 107.3 5.7 4.3e-31 107.1 1.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) HEAT_2 PF13646.6 RUS89929.1 - 0.0018 18.6 0.6 58 4.2 0.0 5.3 5 0 0 5 5 5 0 HEAT repeats HEAT PF02985.22 RUS89929.1 - 0.056 13.7 1.5 12 6.5 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 RUS89929.1 - 0.16 12.0 8.4 0.025 14.6 1.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RUS89929.1 - 1.2 9.4 5.6 1.2 9.4 0.1 3.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase_Tyr PF07714.17 RUS89930.1 - 3.4e-36 124.8 0.0 5.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS89930.1 - 6.8e-35 120.7 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 RUS89930.1 - 9.5e-11 41.0 0.2 1.8e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 RUS89930.1 - 2.9e-09 37.9 8.3 2.9e-09 37.9 8.3 2.2 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 RUS89930.1 - 4.7e-05 22.3 0.0 0.00028 19.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 RUS89930.1 - 0.00051 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 m04gp34like PF12216.8 RUS89930.1 - 0.0078 15.8 0.4 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Immune evasion protein S1FA PF04689.13 RUS89930.1 - 0.026 14.7 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Haspin_kinase PF12330.8 RUS89930.1 - 0.16 10.8 0.1 0.49 9.3 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Cadherin_C_2 PF16492.5 RUS89930.1 - 0.18 12.6 0.9 1.1 10.0 0.1 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PRELI PF04707.14 RUS89931.1 - 1.9e-49 167.5 0.2 2.9e-49 166.9 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 RUS89931.1 - 5.1e-41 140.0 0.0 1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RUS89931.1 - 7.6e-07 29.2 0.1 1.9e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Tcell_CD4_C PF12104.8 RUS89932.1 - 6.3e-05 22.8 0.0 26 4.9 0.0 4.4 4 0 0 4 4 4 0 T cell CD4 receptor C terminal region TBCA PF02970.16 RUS89932.1 - 0.00065 20.0 0.8 2.1 8.7 0.0 2.8 1 1 2 3 3 3 2 Tubulin binding cofactor A ECR1_N PF14382.6 RUS89932.1 - 0.0017 18.1 0.0 82 3.1 0.0 4.5 2 2 1 5 5 5 0 Exosome complex exonuclease RRP4 N-terminal region Nanovirus_coat PF04660.12 RUS89932.1 - 0.0028 17.7 0.1 5.1 7.1 0.0 3.4 1 1 3 4 4 4 1 Nanovirus coat protein KH_5 PF13184.6 RUS89932.1 - 0.0058 16.7 0.1 1.6 8.9 0.0 3.0 1 1 1 2 2 2 1 NusA-like KH domain Toxin_7 PF05980.12 RUS89932.1 - 0.02 15.1 3.5 91 3.4 0.0 4.7 5 0 0 5 5 5 0 Toxin 7 Spc7 PF08317.11 RUS89932.1 - 0.022 13.7 2.6 0.021 13.7 1.9 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 RUS89932.1 - 0.03 13.3 3.9 0.036 13.0 3.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 RUS89932.1 - 0.037 13.6 3.7 0.042 13.4 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ST7 PF04184.12 RUS89932.1 - 0.042 12.3 4.4 1.3 7.4 0.5 2.9 1 1 1 2 2 2 0 ST7 protein Alpha-mann_mid PF09261.11 RUS89932.1 - 0.067 13.3 7.0 0.99 9.6 4.2 2.8 1 1 1 2 2 2 0 Alpha mannosidase middle domain FAD_binding_4 PF01565.23 RUS89932.1 - 0.13 12.0 0.0 40 3.9 0.0 2.6 1 1 0 2 2 2 0 FAD binding domain Semialdhyde_dh PF01118.24 RUS89932.1 - 0.18 12.3 2.1 1.9 9.0 0.1 2.5 1 1 2 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain CRS1_YhbY PF01985.21 RUS89932.1 - 0.21 11.8 4.0 2.7 8.2 0.1 3.0 1 1 1 2 2 2 0 CRS1 / YhbY (CRM) domain PLDc_2 PF13091.6 RUS89933.1 - 3.2e-10 40.0 0.0 4.1e-05 23.5 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RUS89933.1 - 0.06 13.6 2.5 0.35 11.1 0.3 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif BSD PF03909.17 RUS89933.1 - 0.15 12.1 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 BSD domain ADP_ribosyl_GH PF03747.14 RUS89934.1 - 1e-50 173.1 0.5 1.2e-50 172.9 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase bZIP_1 PF00170.21 RUS89935.1 - 9.5e-10 38.4 7.5 1.8e-09 37.5 7.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RUS89935.1 - 1.6e-05 24.9 9.6 2.4e-05 24.3 9.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RUS89935.1 - 0.00065 20.2 2.6 0.0012 19.3 2.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 RUS89935.1 - 0.06 13.5 4.1 0.17 12.1 3.9 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TGF_beta PF00019.20 RUS89938.1 - 2.9e-23 82.8 1.3 8.9e-23 81.3 1.3 1.9 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS89938.1 - 0.049 13.4 10.1 0.087 12.6 4.3 3.4 2 1 0 2 2 2 0 TGF-beta propeptide DUF5473 PF17567.2 RUS89939.1 - 0.0093 16.2 3.5 0.017 15.4 3.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5473) NAD_binding_10 PF13460.6 RUS89940.1 - 5.9e-42 143.6 0.0 6.7e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RUS89940.1 - 2.2e-10 40.5 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 RUS89940.1 - 3.7e-07 29.8 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 RUS89940.1 - 0.022 14.6 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Rimk_N PF18030.1 RUS89940.1 - 0.035 14.5 0.2 0.13 12.7 0.2 1.8 1 1 0 1 1 1 0 RimK PreATP-grasp domain RmlD_sub_bind PF04321.17 RUS89940.1 - 0.044 12.9 0.1 2.6 7.1 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 RUS89940.1 - 0.082 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Amdase PF17645.1 RUS89940.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase TrkA_N PF02254.18 RUS89940.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 RUS89940.1 - 0.18 11.9 0.2 0.42 10.7 0.1 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Gtr1_RagA PF04670.12 RUS89941.1 - 1.8e-106 354.7 0.9 2.4e-106 354.3 0.9 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 RUS89941.1 - 1.3e-09 37.9 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS89941.1 - 2.4e-09 37.5 0.0 7.8e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS89941.1 - 2.6e-08 33.5 0.0 6.2e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS89941.1 - 6.8e-07 29.4 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS89941.1 - 0.00077 19.1 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS89941.1 - 0.02 14.8 0.4 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 RUS89941.1 - 0.022 14.5 2.1 0.09 12.5 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 RUS89941.1 - 0.034 14.7 0.0 0.098 13.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 RUS89941.1 - 0.037 13.2 1.3 0.3 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 RUS89941.1 - 0.038 13.7 0.2 0.15 11.8 0.1 2.0 3 0 0 3 3 3 0 AAA domain SecA_SW PF07516.13 RUS89941.1 - 0.055 13.5 1.2 0.078 13.0 1.2 1.4 1 1 0 1 1 1 0 SecA Wing and Scaffold domain SRPRB PF09439.10 RUS89941.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF72 PF01904.18 RUS89941.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF72 G-alpha PF00503.20 RUS89941.1 - 2.3 7.3 6.5 13 4.9 0.0 2.8 1 1 1 3 3 3 0 G-protein alpha subunit SIT PF15330.6 RUS89943.1 - 0.053 14.0 0.1 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2729 PF10870.8 RUS89943.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) CBM_14 PF01607.24 RUS89944.1 - 5.2e-06 26.5 9.5 0.032 14.4 0.9 4.2 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain CDC45 PF02724.14 RUS89944.1 - 0.23 9.7 28.2 0.28 9.4 28.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4228 PF14009.6 RUS89944.1 - 1.5 9.2 15.7 3.1 8.2 15.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Presenilin PF01080.17 RUS89944.1 - 1.9 7.2 22.8 2.5 6.8 22.8 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 RUS89944.1 - 2.5 7.9 37.3 3.2 7.5 37.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pro_CA PF00484.19 RUS89945.1 - 2.3e-27 96.2 0.0 5.8e-27 94.9 0.0 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Somatomedin_B PF01033.17 RUS89947.1 - 2.5e-07 31.0 8.0 2.5e-07 31.0 8.0 2.7 2 0 0 2 2 2 1 Somatomedin B domain C4bp_oligo PF18453.1 RUS89948.1 - 8.9e-06 25.8 35.5 0.77 10.0 0.4 9.2 4 2 5 9 9 9 7 Oligomerization domain of C4b-binding protein alpha MSG PF02349.15 RUS89948.1 - 0.013 15.6 33.8 0.93 9.7 2.5 5.5 1 1 4 5 5 5 0 Major surface glycoprotein TPR_8 PF13181.6 RUS89948.1 - 2.6 8.5 11.8 3.1e+02 2.0 0.0 7.3 4 2 10 14 14 14 0 Tetratricopeptide repeat An_peroxidase PF03098.15 RUS89949.1 - 1.2e-96 324.4 0.1 1.1e-43 149.7 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase YycI PF09648.10 RUS89949.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 YycH protein Lectin_C PF00059.21 RUS89950.1 - 1.3e-14 54.9 1.6 2.9e-14 53.7 1.6 1.6 1 0 0 1 1 1 1 Lectin C-type domain PAN_1 PF00024.26 RUS89950.1 - 1.5e-05 24.8 0.3 4.1e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 PAN domain Chondroitinas_B PF14592.6 RUS89950.1 - 0.027 13.4 0.1 5.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Chondroitinase B Cu-oxidase_4 PF02578.15 RUS89950.1 - 0.18 11.4 0.8 0.28 10.8 0.8 1.2 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Atg14 PF10186.9 RUS89951.1 - 1.4e-12 47.3 16.5 9.4e-12 44.6 16.5 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 RUS89951.1 - 1.9e-07 30.4 6.5 0.0044 16.0 0.0 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting 38 Ras PF00071.22 RUS89954.1 - 1e-59 200.7 0.2 1.3e-59 200.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS89954.1 - 2e-36 124.8 0.1 3.6e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS89954.1 - 1e-15 57.6 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RUS89954.1 - 1.5e-06 27.8 0.1 3.1e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS89954.1 - 2.5e-06 27.2 0.1 1.5e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS89954.1 - 3e-05 24.1 0.0 5.5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS89954.1 - 0.00013 21.4 0.2 0.00016 21.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS89954.1 - 0.00032 20.6 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RUS89954.1 - 0.012 15.1 0.1 0.17 11.4 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 RUS89954.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-C2H2 PF00096.26 RUS89955.1 - 4.8e-12 45.6 36.2 0.00047 20.5 2.0 6.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 RUS89955.1 - 8.2e-11 41.5 12.3 8.7e-07 28.6 3.3 4.8 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 RUS89955.1 - 3.7e-06 27.1 36.6 0.00012 22.4 0.6 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS89955.1 - 7.4e-06 26.4 39.9 0.03 15.2 2.3 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger OrsD PF12013.8 RUS89955.1 - 0.32 11.4 11.0 0.26 11.8 0.6 3.5 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-MYST PF17772.1 RUS89955.1 - 0.83 9.3 4.5 0.86 9.3 0.0 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain zf_UBZ PF18439.1 RUS89955.1 - 1 9.0 7.4 0.19 11.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 RUS89955.1 - 8 6.2 14.3 13 5.6 0.1 4.0 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain ERAP1_C PF11838.8 RUS89956.1 - 6.7e-35 121.1 0.2 8.1e-35 120.9 0.2 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain INTS2 PF14750.6 RUS89956.1 - 0.083 10.4 0.0 0.098 10.2 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 Peptidase_M1 PF01433.20 RUS89957.1 - 8.8e-79 264.1 0.1 1.4e-78 263.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RUS89957.1 - 2.2e-42 145.3 0.3 3.2e-42 144.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 RUS89957.1 - 1e-23 84.4 0.0 2.5e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M61 PF05299.12 RUS89957.1 - 2.1 8.8 3.9 41 4.6 2.4 3.3 3 1 0 3 3 3 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 RUS89958.1 - 1.2e-81 273.4 0.2 2e-81 272.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 RUS89958.1 - 8.8e-40 136.9 0.4 1e-37 130.1 0.0 2.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 RUS89958.1 - 3e-25 89.4 2.8 3.3e-25 89.3 0.3 2.2 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Aminopep PF10023.9 RUS89958.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase DUF4573 PF15140.6 RUS89959.1 - 9.5e-13 48.3 35.2 5.9e-07 29.4 25.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Tcp10_C PF07202.13 RUS89959.1 - 8.5e-10 38.9 8.7 4.9e-08 33.1 2.1 2.7 1 1 2 3 3 3 3 T-complex protein 10 C-terminus Plasmodium_HRP PF05403.11 RUS89959.1 - 0.0037 17.1 16.0 0.31 10.8 8.2 2.4 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) HisG PF01634.18 RUS89959.1 - 0.0048 16.9 0.4 38 4.2 0.0 5.0 1 1 2 3 3 3 0 ATP phosphoribosyltransferase VWD PF00094.25 RUS89959.1 - 0.68 10.2 14.8 0.97 9.7 2.9 2.8 1 1 1 2 2 2 0 von Willebrand factor type D domain Lectin_N PF03954.14 RUS89961.1 - 0.062 13.1 2.6 0.32 10.8 0.1 2.2 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF948 PF06103.11 RUS89961.1 - 0.36 11.1 3.2 8.8 6.7 0.0 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.11 RUS89961.1 - 3.4 8.4 10.0 5.4 7.7 2.3 2.7 1 1 1 2 2 2 0 Cytochrome b562 Ribo_biogen_C PF04034.13 RUS89962.1 - 0.14 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal 7tm_1 PF00001.21 RUS89963.1 - 1.8e-15 57.0 6.0 3.8e-13 49.4 12.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Connexin PF00029.19 RUS89963.1 - 2.4e-05 24.2 0.6 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Connexin SDA1 PF05285.12 RUS89963.1 - 0.00029 20.4 9.2 0.00029 20.4 9.2 1.4 2 0 0 2 2 1 1 SDA1 Sigma70_ner PF04546.13 RUS89963.1 - 0.00064 19.7 6.0 0.00096 19.1 6.0 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region CPSF100_C PF13299.6 RUS89963.1 - 0.0041 17.3 0.4 0.0067 16.6 0.4 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DUF719 PF05334.13 RUS89963.1 - 0.0062 16.8 0.6 0.011 16.0 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF719) TRAP_alpha PF03896.16 RUS89963.1 - 0.0078 15.4 6.8 0.016 14.4 6.8 1.5 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 RUS89963.1 - 0.008 15.2 0.1 0.016 14.2 0.0 1.6 2 0 0 2 2 1 1 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 RUS89963.1 - 0.011 16.2 0.1 0.017 15.6 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RXT2_N PF08595.11 RUS89963.1 - 0.02 14.9 5.4 0.03 14.3 5.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal SpoIIP PF07454.11 RUS89963.1 - 0.02 14.4 2.9 0.031 13.8 2.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 RUS89963.1 - 0.027 15.4 4.1 0.17 12.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 RUS89963.1 - 0.036 12.0 1.7 0.062 11.2 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4471 PF14740.6 RUS89963.1 - 0.041 13.1 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Presenilin PF01080.17 RUS89963.1 - 0.049 12.4 2.8 0.05 12.4 0.0 2.3 2 0 0 2 2 2 0 Presenilin Eapp_C PF10238.9 RUS89963.1 - 0.05 13.7 1.3 0.099 12.7 1.3 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein RAB3GAP2_C PF14656.6 RUS89963.1 - 0.052 11.8 2.1 0.095 10.9 2.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MAS20 PF02064.15 RUS89963.1 - 0.055 13.6 2.1 0.091 12.9 2.1 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Pox_Ag35 PF03286.14 RUS89963.1 - 0.057 13.2 10.8 0.095 12.5 10.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4337 PF14235.6 RUS89963.1 - 0.13 12.3 1.6 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) SspB PF04386.13 RUS89963.1 - 0.2 11.6 5.5 0.48 10.3 5.5 1.6 1 0 0 1 1 1 0 Stringent starvation protein B EIIBC-GUT_N PF03612.14 RUS89963.1 - 0.24 11.1 2.9 0.41 10.4 2.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 RUS89963.1 - 0.31 11.4 1.9 0.58 10.5 1.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UPF0182 PF03699.13 RUS89963.1 - 0.32 9.1 5.4 3.8 5.5 5.5 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) NARP1 PF12569.8 RUS89963.1 - 0.33 9.8 5.7 0.47 9.3 5.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RED_N PF07808.13 RUS89963.1 - 0.62 9.6 12.3 0.92 9.0 12.3 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region D123 PF07065.14 RUS89963.1 - 0.71 9.0 3.8 1.1 8.4 3.8 1.2 1 0 0 1 1 1 0 D123 Astro_capsid_p PF12226.8 RUS89963.1 - 1.2 8.2 11.1 1.7 7.7 11.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2052 PF09747.9 RUS89963.1 - 1.7 8.7 20.9 2.9 8.0 20.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GNAT_acetyltr_2 PF13718.6 RUS89963.1 - 2.7 7.3 4.8 4.6 6.6 4.8 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RPA43_OB PF17875.1 RUS89963.1 - 3.3 8.4 8.4 5.8 7.6 8.4 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Mpp10 PF04006.12 RUS89963.1 - 3.3 6.0 23.1 4.6 5.6 23.1 1.0 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.11 RUS89963.1 - 3.6 6.0 9.1 5.3 5.5 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 G0-G1_switch_2 PF15103.6 RUS89963.1 - 3.6 8.1 7.3 1.3 9.5 3.3 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 NOA36 PF06524.12 RUS89963.1 - 4.4 6.5 19.9 7 5.9 19.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4628 PF15429.6 RUS89963.1 - 4.5 6.9 6.3 7.5 6.1 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) MIF4G_like_2 PF09090.11 RUS89963.1 - 7.2 6.0 8.2 14 5.1 8.2 1.4 1 0 0 1 1 1 0 MIF4G like BUD22 PF09073.10 RUS89963.1 - 7.9 5.7 18.6 11 5.2 18.6 1.1 1 0 0 1 1 1 0 BUD22 Med17 PF10156.9 RUS89963.1 - 8.1 5.0 11.8 12 4.4 11.8 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex AIM3 PF17096.5 RUS89963.1 - 9 7.3 5.4 16 6.5 5.4 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF5523 PF17661.1 RUS89963.1 - 9 5.9 21.9 13 5.4 21.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF5325 PF17259.2 RUS89967.1 - 0.067 13.1 10.7 8.7 6.3 0.4 4.2 1 1 2 5 5 5 0 Family of unknown function (DUF5325) DUF3087 PF11286.8 RUS89967.1 - 1.1 8.7 26.9 0.94 8.9 4.5 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3087) BP28CT PF08146.12 RUS89967.1 - 4 7.3 29.6 18 5.1 3.2 4.8 1 1 3 4 4 4 0 BP28CT (NUC211) domain EF-hand_6 PF13405.6 RUS89968.1 - 6.6e-05 22.5 0.2 0.00011 21.8 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RUS89968.1 - 0.00025 21.4 0.1 0.0004 20.8 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS89968.1 - 0.0019 17.6 0.4 0.0027 17.1 0.4 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 RUS89968.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS89968.1 - 0.2 11.2 0.4 0.35 10.4 0.4 1.3 1 0 0 1 1 1 0 EF hand SPX PF03105.19 RUS89968.1 - 2.5 7.9 15.9 3.8 7.3 15.9 1.3 1 0 0 1 1 1 0 SPX domain DUF1472 PF07339.12 RUS89969.1 - 0.06 13.9 50.4 1.1e+02 3.5 0.2 13.2 1 1 13 14 14 14 0 Protein of unknown function (DUF1472) AAA_12 PF13087.6 RUS89970.1 - 1.5e-40 139.0 0.1 3.5e-40 137.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RUS89970.1 - 8.8e-28 97.8 4.3 2.9e-13 50.2 1.9 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RUS89970.1 - 5.5e-11 43.0 0.0 4.6e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RUS89970.1 - 9e-08 32.1 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 RUS89970.1 - 8e-05 22.3 1.1 0.0013 18.3 1.1 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 RUS89970.1 - 0.00013 22.2 0.9 0.14 12.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.9 RUS89970.1 - 0.0004 19.7 0.2 0.0025 17.1 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RUS89970.1 - 0.0047 17.0 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RUS89970.1 - 0.021 14.3 0.3 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 RUS89970.1 - 0.021 14.6 3.7 0.12 12.2 0.0 3.1 4 0 0 4 4 4 0 DEAD/DEAH box helicase NB-LRR PF12061.8 RUS89970.1 - 0.058 12.7 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Late blight resistance protein R1 Pox_M2 PF04887.12 RUS89971.1 - 0.074 12.5 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein Gly_acyl_tr_N PF06021.11 RUS89972.1 - 3.2e-05 24.1 0.0 0.0014 18.8 0.0 2.1 1 1 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase FR47 PF08445.10 RUS89972.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Gly_acyl_tr_C PF08444.10 RUS89972.1 - 0.0037 17.5 0.0 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Exo_endo_phos_2 PF14529.6 RUS89973.1 - 3.5e-13 49.4 0.0 7.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 RUS89973.1 - 4.2e-07 29.7 0.0 9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 RUS89973.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MRP-S28 PF10213.9 RUS89973.1 - 0.06 13.8 6.5 0.043 14.2 4.2 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein UvrD-helicase PF00580.21 RUS89973.1 - 0.17 11.3 7.5 0.31 10.5 7.5 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Elong_Iki1 PF10483.9 RUS89974.1 - 2.4e-23 83.1 0.7 5.4e-14 52.4 0.0 2.0 1 1 1 2 2 2 2 Elongator subunit Iki1 DUF3827 PF12877.7 RUS89976.1 - 1.4e-14 53.4 0.0 1.4e-14 53.4 0.0 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF3827) FAM163 PF15069.6 RUS89976.1 - 0.012 16.1 1.3 0.012 16.1 1.3 3.1 3 1 0 3 3 3 0 FAM163 family EphA2_TM PF14575.6 RUS89976.1 - 0.042 14.7 0.0 0.042 14.7 0.0 3.0 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS89976.1 - 0.055 13.7 0.2 0.055 13.7 0.2 3.2 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator AbrB-like PF14250.6 RUS89976.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 AbrB-like transcriptional regulator PRIMA1 PF16101.5 RUS89976.1 - 0.18 11.9 3.7 0.29 11.2 0.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Tweety PF04906.13 RUS89976.1 - 0.31 9.7 0.1 0.63 8.6 0.0 1.4 2 0 0 2 2 2 0 Tweety Pkinase PF00069.25 RUS89977.1 - 1.7e-71 240.7 0.0 2.5e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS89977.1 - 3e-37 128.3 0.0 5.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS89977.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS89977.1 - 0.005 16.2 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4768 PF15989.5 RUS89978.1 - 2.2 8.3 20.5 10 6.1 1.5 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4768) DUF1924 PF09086.11 RUS89978.1 - 4.8 7.6 10.5 80 3.7 0.3 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF1924) EutK_C PF16365.5 RUS89979.1 - 0.045 13.8 0.4 15 5.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus Prok-E2_B PF14461.6 RUS89979.1 - 0.26 11.0 1.0 7 6.4 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family B Use1 PF09753.9 RUS89980.1 - 3e-06 27.1 0.0 3.8e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 RUS89980.1 - 9.9e-05 22.2 0.1 0.00028 20.8 0.1 1.7 1 1 0 1 1 1 1 Sec20 Sigma_reg_N PF13800.6 RUS89980.1 - 0.045 14.0 1.0 0.086 13.1 1.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4407 PF14362.6 RUS89980.1 - 0.045 13.1 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp PF00026.23 RUS89981.1 - 8.3e-96 321.1 0.2 9.7e-96 320.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RUS89981.1 - 1.9e-16 60.8 0.2 9.1e-15 55.3 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RUS89981.1 - 1.6e-05 25.5 0.3 0.012 16.2 0.1 3.4 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 RUS89981.1 - 0.023 15.3 0.0 0.49 11.0 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Lig_chan PF00060.26 RUS89982.1 - 1.1e-07 31.8 0.1 2.1e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS89982.1 - 4.7e-07 30.0 0.0 9.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS89982.1 - 0.0048 16.4 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Complex1_LYR PF05347.15 RUS89984.1 - 1.2e-11 44.5 0.1 1.9e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RUS89984.1 - 2.8e-08 34.4 0.7 3.8e-08 34.0 0.7 1.3 1 1 0 1 1 1 1 Complex1_LYR-like 7TM_GPCR_Srx PF10328.9 RUS89985.1 - 0.0014 18.3 21.5 0.0015 18.2 19.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 RUS89985.1 - 0.036 14.1 0.3 0.12 12.5 0.3 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2663 PF10864.8 RUS89985.1 - 0.28 11.6 3.0 0.58 10.6 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2663) 7tm_1 PF00001.21 RUS89985.1 - 1.7 7.9 21.2 1.3 8.3 18.2 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) IL17 PF06083.11 RUS89987.1 - 1.7e-07 31.6 2.4 2.7e-07 31.0 2.4 1.3 1 0 0 1 1 1 1 Interleukin-17 Syja_N PF02383.18 RUS89988.1 - 2.3e-67 227.6 0.2 3.9e-67 226.9 0.2 1.4 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.11 RUS89988.1 - 9.6e-27 93.6 0.1 1.9e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 RUS89988.1 - 1.1e-13 51.2 0.1 2.2e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3703 PF12487.8 RUS89989.1 - 0.29 11.0 7.6 2.1 8.2 1.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3703) Pet191_N PF10203.9 RUS89989.1 - 0.38 11.1 6.5 2.3 8.6 1.0 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 HCMVantigenic_N PF12154.8 RUS89989.1 - 2.5 8.3 12.0 2.5 8.3 0.5 3.9 3 1 0 3 3 3 0 Glycoprotein B N-terminal antigenic domain of HCMV Sulfotransfer_1 PF00685.27 RUS89990.1 - 1.2e-45 156.1 0.9 3.1e-45 154.7 0.9 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS89990.1 - 2.2e-09 38.0 0.1 2.3e-08 34.7 0.0 2.1 1 1 0 2 2 2 1 Sulfotransferase family 7tm_1 PF00001.21 RUS89991.1 - 1.1e-16 61.0 12.1 1.4e-16 60.6 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS89991.1 - 0.013 14.8 9.3 0.041 13.2 9.3 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw GAPT PF11770.8 RUS89991.1 - 0.16 11.8 0.8 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Amino_oxidase PF01593.24 RUS89994.1 - 9.5e-40 137.2 0.0 1.1e-39 137.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RUS89994.1 - 4.9e-12 45.9 0.0 8.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RUS89994.1 - 1.9e-05 24.4 0.0 0.00016 21.4 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 RUS89994.1 - 0.00037 19.8 0.1 0.00064 19.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 RUS89994.1 - 0.0031 16.7 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RUS89994.1 - 0.042 12.6 0.1 0.07 11.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 RUS89994.1 - 0.15 12.0 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 RUS89994.1 - 0.19 10.9 0.1 0.58 9.3 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 RUS89994.1 - 0.24 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family Epimerase PF01370.21 RUS89995.1 - 5.3e-23 81.7 0.0 7.6e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS89995.1 - 9.3e-17 60.9 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 RUS89995.1 - 7.4e-13 48.6 0.0 9.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 RUS89995.1 - 5.3e-12 45.5 0.0 9.1e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RUS89995.1 - 3.3e-11 43.4 0.0 5.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RUS89995.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 RUS89995.1 - 0.0012 18.8 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 RUS89995.1 - 0.0018 17.8 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 RUS89995.1 - 0.0056 15.9 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 RUS89995.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain SBP_bac_11 PF13531.6 RUS89995.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein LCM PF04072.14 RUS89995.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase DUF3368 PF11848.8 RUS89995.1 - 0.19 11.5 0.6 1 9.2 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) KxDL PF10241.9 RUS89996.1 - 0.095 13.0 0.4 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein TolA_bind_tri PF16331.5 RUS89996.1 - 2.2 8.4 12.2 0.35 11.0 0.9 3.4 5 0 0 5 5 5 0 TolA binding protein trimerisation PCI PF01399.27 RUS89997.1 - 9.8e-18 64.6 1.7 9.8e-18 64.6 1.7 2.0 3 0 0 3 3 3 1 PCI domain RhoGEF PF00621.20 RUS89998.1 - 1.5e-40 139.4 1.2 4.8e-40 137.7 1.2 1.9 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 RUS89998.1 - 4.7e-08 32.5 0.2 4.7e-08 32.5 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 RUS89998.1 - 1e-07 31.5 0.0 2.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RUS89998.1 - 8.8e-07 28.7 0.6 8.8e-07 28.7 0.6 2.1 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 RUS89998.1 - 2e-06 28.3 0.1 5.2e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 RUS89998.1 - 7.1e-06 26.3 0.1 1.8e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF325 PF03804.13 RUS89998.1 - 0.15 12.1 0.1 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Viral proteins of unknown function DUF3755 PF12579.8 RUS89998.1 - 0.26 10.9 1.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) BES1_N PF05687.13 RUS89998.1 - 3.6 8.0 7.0 9.8 6.5 7.0 1.7 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal CRAL_TRIO_2 PF13716.6 RUS89999.1 - 1.1e-08 35.4 0.0 4.2e-08 33.4 0.0 1.9 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain Peroxin-22 PF12827.7 RUS89999.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family TIR_2 PF13676.6 RUS90000.1 - 1.1e-18 68.0 0.3 1.7e-08 35.0 0.0 3.3 3 0 0 3 3 3 2 TIR domain COR PF16095.5 RUS90000.1 - 8e-07 29.1 0.2 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain TIR PF01582.20 RUS90000.1 - 0.00072 19.4 4.1 0.41 10.4 2.5 3.4 2 1 0 2 2 2 2 TIR domain SOG2 PF10428.9 RUS90000.1 - 0.0041 16.4 0.0 0.0041 16.4 0.0 3.1 3 1 0 3 3 3 1 RAM signalling pathway protein DOMON PF03351.17 RUS90001.1 - 8.3e-14 51.9 0.9 2e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 DOMON domain DUF1181 PF06680.11 RUS90001.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) UBA PF00627.31 RUS90002.1 - 1.9e-07 30.8 0.2 4.9e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 RUS90002.1 - 2.3e-05 24.1 0.1 5.9e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.23 RUS90002.1 - 0.00039 20.1 0.1 0.001 18.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family CUE PF02845.16 RUS90002.1 - 0.015 15.0 0.4 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 CUE domain STI1 PF17830.1 RUS90002.1 - 0.036 14.0 0.3 11 6.0 0.0 2.6 1 1 1 2 2 2 0 STI1 domain RT_RNaseH_2 PF17919.1 RUS90003.1 - 7.2e-32 109.4 0.1 1.9e-31 108.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS90003.1 - 1.8e-24 86.0 0.0 4.8e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS90003.1 - 8.7e-18 64.6 0.0 2.4e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS90003.1 - 1e-14 54.3 0.0 2.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 RUS90003.1 - 3.5e-08 33.2 0.1 6.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 RUS90003.1 - 5.4e-06 26.5 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF4100 PF13352.6 RUS90003.1 - 0.0055 16.5 0.1 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4100) RVT_3 PF13456.6 RUS90003.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Asp_protease_2 PF13650.6 RUS90003.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 RUS90003.1 - 0.091 13.3 0.0 0.29 11.7 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H3C2 PF16721.5 RUS90003.1 - 0.15 12.4 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding Macro PF01661.21 RUS90004.1 - 4.2e-22 78.4 0.4 1.1e-08 35.1 0.0 3.9 3 0 0 3 3 3 3 Macro domain RRM_1 PF00076.22 RUS90004.1 - 5.6e-05 22.9 0.0 0.16 11.8 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 RUS90004.1 - 0.00093 19.8 2.2 3.6 8.3 0.0 5.1 5 0 0 5 5 5 1 Nmi/IFP 35 domain (NID) DUF2292 PF10055.9 RUS90004.1 - 0.071 12.8 0.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Attractin PF08037.11 RUS90004.1 - 0.12 12.4 1.2 0.62 10.1 1.2 2.3 1 0 0 1 1 1 0 Attractin family DUF1137 PF06587.11 RUS90004.1 - 0.12 12.4 0.2 0.34 10.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) Ribosomal_L38e PF01781.18 RUS90004.1 - 0.67 10.1 5.6 12 6.1 0.1 4.1 4 0 0 4 4 4 0 Ribosomal L38e protein family BTB_2 PF02214.22 RUS90005.1 - 3e-11 43.5 0.0 4.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 RUS90005.1 - 0.06 13.5 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain LIF_OSM PF01291.17 RUS90006.1 - 6 7.0 16.3 36 4.5 0.2 5.9 1 1 7 8 8 8 0 LIF / OSM family RPM2 PF08579.11 RUS90007.1 - 5.5e-05 23.5 16.5 1.6 9.1 2.8 5.1 1 1 1 2 2 2 2 Mitochondrial ribonuclease P subunit (RPM2) RRM_3 PF08777.11 RUS90008.1 - 3.5e-20 72.0 0.5 3.5e-20 72.0 0.5 2.6 2 0 0 2 2 2 1 RNA binding motif La PF05383.17 RUS90008.1 - 1.2e-18 66.9 0.1 3.6e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 RUS90008.1 - 2.1e-12 46.7 0.5 3.6e-09 36.3 0.8 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_binding PF10199.9 RUS90008.1 - 0.56 10.8 10.3 0.25 12.0 2.4 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Sacchrp_dh_NADP PF03435.18 RUS90010.1 - 8.7e-20 71.3 0.0 1.2e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 RUS90010.1 - 0.15 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding TraV PF09676.10 RUS90012.1 - 4.5 8.3 7.5 5.4 8.0 2.2 2.4 1 1 1 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) BetaGal_dom2 PF10435.9 RUS90013.1 - 4.5e-08 33.1 38.6 0.12 12.2 0.8 8.3 1 1 10 11 11 11 10 Beta-galactosidase, domain 2 DUF4402 PF14352.6 RUS90013.1 - 1.3e-05 25.9 24.0 5.6e+03 -2.1 23.5 4.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) Toast_rack_N PF17115.5 RUS90013.1 - 0.00017 21.8 35.9 20 5.6 0.4 12.3 1 1 7 8 8 8 2 N-terminal domain of toast_rack, DUF2154 Plasmodium_HRP PF05403.11 RUS90013.1 - 0.0012 18.7 4.0 0.0012 18.7 4.0 2.4 2 1 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) Flagellin_D3 PF08884.11 RUS90013.1 - 3.4 8.1 23.4 93 3.5 3.0 6.7 1 1 6 7 7 7 0 Flagellin D3 domain Proteasom_Rpn13 PF04683.13 RUS90013.1 - 7.5 7.2 22.3 3.2e+02 2.0 0.0 7.6 1 1 2 3 3 3 0 Proteasome complex subunit Rpn13 ubiquitin receptor NDK PF00334.19 RUS90014.1 - 0.0005 20.1 0.0 0.079 13.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase LEA_3 PF03242.13 RUS90015.1 - 0.002 18.8 6.3 24 5.8 0.2 6.4 1 1 7 8 8 8 2 Late embryogenesis abundant protein Ric8 PF10165.9 RUS90015.1 - 0.0057 15.7 15.9 6.3 5.7 2.9 5.7 1 1 1 2 2 2 1 Guanine nucleotide exchange factor synembryn 2C_adapt PF08793.10 RUS90015.1 - 0.021 15.0 0.0 16 5.7 0.0 3.1 2 0 0 2 2 2 0 2-cysteine adaptor domain NDK PF00334.19 RUS90016.1 - 3e-22 79.1 0.0 1.1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF2790 PF10976.8 RUS90017.1 - 2.1e-08 34.1 18.0 0.011 15.7 0.1 5.8 1 1 4 5 5 5 5 Protein of unknown function (DUF2790) Bact_transglu_N PF08379.10 RUS90017.1 - 0.22 12.5 42.0 34 5.4 0.3 8.7 1 1 8 9 9 9 0 Bacterial transglutaminase-like N-terminal region Glyco_hydro_25 PF01183.20 RUS90017.1 - 0.26 11.5 12.4 21 5.2 0.3 4.8 1 1 5 6 6 6 0 Glycosyl hydrolases family 25 MgrB PF13998.6 RUS90019.1 - 0.2 11.6 7.8 27 4.8 0.2 3.5 3 0 0 3 3 3 0 MgrB protein KRE1 PF17056.5 RUS90019.1 - 0.22 11.3 0.1 23 4.8 0.0 2.2 1 1 1 2 2 2 0 Killer toxin-resistance protein 1 Ig_3 PF13927.6 RUS90021.1 - 2.4e-06 28.0 0.0 5.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS90021.1 - 1.3e-05 25.2 0.0 6e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS90021.1 - 1.9e-05 24.9 0.0 4.6e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain NOA36 PF06524.12 RUS90021.1 - 0.0015 18.0 10.7 0.002 17.5 10.7 1.2 1 0 0 1 1 1 1 NOA36 protein RXT2_N PF08595.11 RUS90021.1 - 0.35 10.9 3.7 0.46 10.5 3.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RUS90021.1 - 0.83 8.7 19.3 1.1 8.3 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2076 PF09849.9 RUS90021.1 - 3.3 7.7 13.0 4.6 7.2 13.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop14 PF04147.12 RUS90021.1 - 5.5 5.1 11.1 6.8 4.8 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS90021.1 - 6.7 4.9 6.6 8.1 4.6 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 RUS90021.1 - 6.8 5.1 6.7 8.2 4.8 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 I-set PF07679.16 RUS90023.1 - 4.2e-41 138.9 0.0 2.2e-14 53.3 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90023.1 - 2.1e-37 127.6 0.2 2.4e-13 50.4 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RUS90023.1 - 4.9e-33 113.3 1.7 1.1e-11 44.9 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS90023.1 - 4.3e-23 81.3 0.9 2.7e-10 40.3 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 RUS90023.1 - 5.8e-13 49.0 8.8 0.012 15.8 0.1 6.5 4 3 1 5 5 5 4 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS90023.1 - 2.2e-10 39.9 0.0 0.0031 17.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS90023.1 - 1.5e-06 28.2 0.2 0.12 12.5 0.1 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 RUS90023.1 - 7e-06 26.0 0.0 0.36 10.9 0.0 3.7 4 0 0 4 4 4 2 C17orf99 Ig domain Ig_4 PF16680.5 RUS90023.1 - 0.00028 21.1 0.0 3.7 7.9 0.0 4.0 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 RUS90023.1 - 0.00062 19.5 0.1 3.1 7.7 0.0 3.3 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 BiPBP_C PF06832.12 RUS90023.1 - 0.031 14.3 0.1 4.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 RUS90023.1 - 0.15 12.2 0.4 3.1 7.9 0.0 3.1 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain zf-C4 PF00105.18 RUS90024.1 - 3e-21 75.7 13.1 5.3e-21 74.9 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS90024.1 - 5.7e-17 62.0 0.4 1.1e-16 61.0 0.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 RUS90024.1 - 0.093 12.8 6.5 0.19 11.8 6.5 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 RUS90024.1 - 4.9 7.3 10.1 3.3e+02 1.4 10.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon RVT_1 PF00078.27 RUS90025.1 - 1.9e-37 128.9 0.1 3.4e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SF3b1 PF08920.10 RUS90026.1 - 2.9e-42 143.9 49.0 2.2e-40 137.8 17.7 5.6 2 1 3 5 5 4 3 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 RUS90026.1 - 1.8e-09 37.9 2.6 0.55 10.8 0.0 7.1 7 1 1 8 8 8 3 HEAT-like repeat HEAT PF02985.22 RUS90026.1 - 2.3e-09 36.7 7.5 0.7 10.3 0.1 8.2 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 RUS90026.1 - 3.9e-08 33.6 6.2 0.036 14.5 0.0 7.1 5 2 4 9 9 9 3 HEAT repeats Vac14_Fab1_bd PF12755.7 RUS90026.1 - 3.8e-05 24.2 1.2 1.3 9.7 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RUS90026.1 - 0.00035 20.7 9.3 2.3 8.2 0.0 6.1 6 2 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 RUS90026.1 - 0.0026 17.7 3.3 1.7 8.5 0.1 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 RUS90026.1 - 0.0041 16.7 1.0 5.1 6.6 0.1 3.1 3 0 0 3 3 3 2 CLASP N terminal TAF6_C PF07571.13 RUS90026.1 - 0.0073 16.6 0.0 0.54 10.6 0.0 3.4 2 1 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain DUF4047 PF13256.6 RUS90026.1 - 0.088 13.0 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Dor1 PF04124.12 RUS90026.1 - 0.1 11.2 1.7 3.9 6.1 0.1 2.7 3 0 0 3 3 3 0 Dor1-like family Med26 PF08711.11 RUS90026.1 - 0.15 12.1 0.0 0.63 10.1 0.0 2.2 1 0 0 1 1 1 0 TFIIS helical bundle-like domain UNC45-central PF11701.8 RUS90026.1 - 0.17 11.9 0.8 0.52 10.3 0.0 2.2 3 0 0 3 3 2 0 Myosin-binding striated muscle assembly central DNA_pol_phi PF04931.13 RUS90026.1 - 0.19 9.8 0.0 6.6 4.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi MAM PF00629.23 RUS90027.1 - 2.2e-44 151.2 0.1 4.4e-44 150.2 0.0 1.5 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu UPF0231 PF06062.11 RUS90027.1 - 0.36 11.1 6.0 7.7 6.8 3.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) DUF4472 PF14739.6 RUS90027.1 - 4 8.2 17.4 2.6 8.8 8.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Orthopox_A49R PF06489.11 RUS90028.1 - 0.016 15.5 0.7 0.49 10.6 0.7 2.4 2 0 0 2 2 2 0 Orthopoxvirus A49R protein Glyco_transf_10 PF00852.19 RUS90029.1 - 9.3e-48 162.3 0.1 1.5e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS90029.1 - 8.7e-14 51.9 0.0 1.9e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Hormone_3 PF00159.18 RUS90029.1 - 0.21 11.7 0.7 0.75 9.9 0.1 2.3 3 0 0 3 3 3 0 Pancreatic hormone peptide Glutaredoxin PF00462.24 RUS90030.1 - 8.2e-38 128.4 0.0 4.2e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin SH3BGR PF04908.15 RUS90030.1 - 7.8e-06 26.0 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 RUS90030.1 - 6.4e-05 23.3 0.0 0.1 13.0 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 RUS90030.1 - 0.00043 20.2 0.0 0.003 17.5 0.0 2.3 2 1 1 3 3 3 1 Thioredoxin RdRP PF05183.12 RUS90030.1 - 0.0072 15.0 0.0 2.3 6.7 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase DUF826 PF05696.11 RUS90030.1 - 0.052 13.6 1.4 25 5.0 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF826) PPR PF01535.20 RUS90030.1 - 0.062 13.6 1.3 15 6.1 0.2 2.6 2 0 0 2 2 2 0 PPR repeat HyaE PF07449.11 RUS90030.1 - 0.14 12.1 0.0 11 6.0 0.0 3.1 3 2 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Mei5 PF10376.9 RUS90031.1 - 8.2e-13 48.7 3.8 8.2e-13 48.7 3.8 2.2 1 1 1 2 2 2 1 Double-strand recombination repair protein Mei5_like PF17021.5 RUS90031.1 - 0.0013 18.7 0.1 0.0024 17.9 0.1 1.4 1 0 0 1 1 1 1 Putative double-strand recombination repair-like EphA2_TM PF14575.6 RUS90032.1 - 0.058 14.3 0.7 0.4 11.6 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 RUS90032.1 - 0.14 12.5 0.0 0.71 10.2 0.0 2.2 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 RUS90032.1 - 0.76 9.7 0.0 0.76 9.7 0.0 3.6 5 1 0 5 5 5 0 TMEM154 protein family DUF3011 PF11218.8 RUS90033.1 - 2.4e-13 50.5 5.2 3.1e-13 50.2 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3011) DUF4535 PF15054.6 RUS90034.1 - 3.3e-07 29.9 0.1 7.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4535) CPT PF07931.12 RUS90034.1 - 0.13 12.1 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mannosyl_trans PF05007.13 RUS90035.1 - 3.7e-78 263.0 20.1 3.7e-78 263.0 20.1 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 RUS90035.1 - 7.9e-13 48.2 30.0 1.1e-12 47.7 30.0 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U RFX5_N PF18326.1 RUS90035.1 - 0.14 12.0 1.5 0.2 11.4 0.4 1.8 2 0 0 2 2 2 0 RFX5 N-terminal domain Glycos_transf_2 PF00535.26 RUS90036.1 - 3.6e-29 101.7 0.0 5.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS90036.1 - 1.5e-12 47.9 0.4 2.4e-12 47.2 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RUS90036.1 - 1.4e-06 27.8 0.1 5.1e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS90036.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 RUS90036.1 - 0.0017 18.3 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 tRNA-synt_2 PF00152.20 RUS90037.1 - 1.1e-103 346.7 0.1 1.4e-103 346.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RUS90037.1 - 7.4e-12 45.1 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 RUS90037.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF1565 PF07602.11 RUS90037.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) CLN6 PF15156.6 RUS90038.1 - 2.1e-112 375.0 9.4 2.4e-112 374.8 9.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 PXT1 PF15214.6 RUS90038.1 - 0.093 13.1 1.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 DUF4636 PF15468.6 RUS90038.1 - 0.37 10.5 1.6 0.87 9.2 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) YL1 PF05764.13 RUS90039.1 - 1.4e-05 25.4 35.1 1.8e-05 25.0 35.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 RUS90039.1 - 0.00015 20.2 27.0 0.00019 19.9 27.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop53 PF07767.11 RUS90039.1 - 0.00043 19.8 31.4 0.00057 19.4 31.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 RUS90039.1 - 0.012 13.9 29.7 0.015 13.6 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS90039.1 - 0.023 14.1 33.3 0.029 13.8 33.3 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RUS90039.1 - 0.025 14.5 15.2 0.03 14.2 15.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Neur_chan_memb PF02932.16 RUS90039.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_polI_A34 PF08208.11 RUS90039.1 - 0.12 12.4 43.7 0.21 11.6 43.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Connexin PF00029.19 RUS90039.1 - 0.13 12.0 8.8 0.2 11.4 8.8 1.4 1 0 0 1 1 1 0 Connexin SRP-alpha_N PF04086.13 RUS90039.1 - 0.23 11.4 27.5 0.31 10.9 27.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.12 RUS90039.1 - 0.97 9.7 15.7 1.3 9.3 15.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.9 RUS90039.1 - 1.3 8.6 39.5 2.1 7.9 39.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec62 PF03839.16 RUS90039.1 - 1.6 8.2 15.2 2.8 7.4 15.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Apt1 PF10351.9 RUS90039.1 - 2.2 7.0 14.3 2.8 6.7 14.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PcfK PF14058.6 RUS90039.1 - 4.2 7.7 23.3 7.7 6.8 23.3 1.4 1 0 0 1 1 1 0 PcfK-like protein 7tm_1 PF00001.21 RUS90040.1 - 7.1e-40 137.0 7.9 9.4e-40 136.6 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS90040.1 - 0.0025 17.5 7.8 0.0025 17.5 7.8 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4440 PF14534.6 RUS90041.1 - 0.13 12.7 0.0 0.36 11.2 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Fez1 PF06818.15 RUS90042.1 - 0.00018 22.0 73.8 0.15 12.5 19.7 4.1 1 1 3 4 4 4 4 Fez1 HMMR_N PF15905.5 RUS90042.1 - 0.00022 20.8 23.4 0.00022 20.8 23.4 4.0 2 2 1 4 4 4 2 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 RUS90042.1 - 0.011 15.9 9.7 0.011 15.9 9.7 6.4 2 2 3 6 6 6 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 RUS90042.1 - 0.011 15.7 1.1 0.011 15.7 1.1 7.7 3 2 4 7 7 7 0 TolA binding protein trimerisation ZapB PF06005.12 RUS90042.1 - 0.14 12.6 75.6 0.053 14.0 7.2 7.6 3 2 4 7 7 7 0 Cell division protein ZapB DUF1664 PF07889.12 RUS90042.1 - 0.66 10.0 34.7 0.26 11.4 5.0 5.4 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) MAD PF05557.13 RUS90042.1 - 1.3 7.3 75.0 0.031 12.6 19.4 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein Docking PF08990.11 RUS90042.1 - 1.5 8.5 5.1 89 2.8 0.0 4.5 5 0 0 5 5 5 0 Erythronolide synthase docking FlaC_arch PF05377.11 RUS90042.1 - 9.9 6.6 35.7 5.6 7.4 1.7 8.0 6 3 0 7 7 7 0 Flagella accessory protein C (FlaC) Filament PF00038.21 RUS90043.1 - 0.00053 19.7 15.3 0.00053 19.7 15.3 4.5 1 1 2 4 4 4 3 Intermediate filament protein FlpD PF02662.16 RUS90043.1 - 0.2 11.6 3.2 4.5 7.3 0.2 3.0 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Macoilin PF09726.9 RUS90043.1 - 0.65 8.5 57.8 0.039 12.5 19.7 3.2 1 1 2 3 3 3 0 Macoilin family GOLGA2L5 PF15070.6 RUS90043.1 - 8.2 5.0 57.1 3.4 6.2 16.5 2.5 1 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 SH3_9 PF14604.6 RUS90044.1 - 4.8e-17 61.6 0.1 6.5e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 RUS90044.1 - 1.2e-16 60.5 0.3 9.5e-09 35.4 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 RUS90044.1 - 1.3e-16 60.0 0.0 1.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 SH3 domain Ank_4 PF13637.6 RUS90044.1 - 2.6e-10 40.6 0.2 3.3e-09 37.1 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS90044.1 - 3.7e-10 40.3 0.0 8e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_2 PF07653.17 RUS90044.1 - 5.9e-09 35.5 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 RUS90044.1 - 9.8e-08 31.7 1.5 0.0017 18.7 0.1 3.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS90044.1 - 2.4e-07 30.9 0.4 0.00027 21.3 0.2 2.8 3 1 0 3 3 3 2 Ankyrin repeat PX PF00787.24 RUS90045.1 - 3.5e-19 68.9 1.7 1e-18 67.4 0.2 2.2 2 0 0 2 2 2 1 PX domain PDZ PF00595.24 RUS90045.1 - 3.3e-16 59.4 0.8 7.6e-16 58.2 0.8 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS90045.1 - 1.6e-15 56.6 0.3 4.9e-15 55.1 0.3 1.8 2 0 0 2 2 2 1 PDZ domain RA PF00788.23 RUS90045.1 - 1e-10 42.1 0.3 2e-10 41.2 0.3 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ_2 PF13180.6 RUS90045.1 - 7e-06 26.3 0.1 2.2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SNX17_FERM_C PF18116.1 RUS90045.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain TLC PF03219.14 RUS90045.1 - 0.032 13.0 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter Tricorn_PDZ PF14685.6 RUS90045.1 - 0.11 12.5 0.5 4.1 7.4 0.2 2.5 1 1 1 2 2 2 0 Tricorn protease PDZ domain RIO1 PF01163.22 RUS90046.1 - 3.5e-51 173.5 0.4 8e-51 172.3 0.4 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 RUS90046.1 - 7.5e-30 103.0 0.5 1.5e-29 102.0 0.5 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 RUS90046.1 - 9.3e-10 38.8 10.1 2.1e-05 24.6 0.3 3.6 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 RUS90046.1 - 1.7e-07 30.8 0.8 2e-06 27.3 0.8 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PadR PF03551.14 RUS90046.1 - 0.0028 17.6 0.9 0.24 11.4 1.3 2.8 2 1 1 3 3 3 2 Transcriptional regulator PadR-like family Pkinase PF00069.25 RUS90046.1 - 0.046 13.1 1.0 0.36 10.1 1.0 2.3 1 1 0 1 1 1 0 Protein kinase domain BRO1 PF03097.18 RUS90047.1 - 2.4e-118 395.4 2.0 2.4e-118 395.4 2.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RUS90047.1 - 7.9e-87 291.3 13.8 7.9e-87 291.3 13.8 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF2312 PF10073.9 RUS90047.1 - 0.14 11.9 1.3 0.54 9.9 1.3 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) HrpB2 PF09487.10 RUS90047.1 - 0.16 12.4 4.9 0.21 12.0 0.1 3.5 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB2) UPF0184 PF03670.13 RUS90047.1 - 0.33 11.4 3.5 2.6 8.5 0.4 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) ING PF12998.7 RUS90047.1 - 6 7.5 7.0 2.4 8.8 2.1 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TMEM169 PF15052.6 RUS90048.1 - 1.3e-43 148.3 2.4 1.6e-43 147.9 2.4 1.1 1 0 0 1 1 1 1 TMEM169 protein family PRKCSH PF07915.13 RUS90049.1 - 1.3e-16 61.4 5.5 1.3e-16 61.4 5.5 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 RUS90049.1 - 5.2e-05 23.0 2.8 0.00018 21.2 2.8 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 RUS90049.1 - 0.0066 16.3 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Styelin PF17562.2 RUS90049.1 - 0.024 15.0 1.2 0.47 10.8 0.4 3.1 2 0 0 2 2 2 0 Styelin DUF3892 PF13031.6 RUS90049.1 - 0.098 13.3 1.6 0.61 10.8 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) DUF445 PF04286.12 RUS90049.1 - 0.33 10.7 15.5 0.6 9.9 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Ribosomal_S20p PF01649.18 RUS90049.1 - 0.4 11.4 3.9 7.5 7.3 0.2 2.8 2 0 0 2 2 2 0 Ribosomal protein S20 DUF1002 PF06207.11 RUS90049.1 - 1.1 8.8 6.7 0.081 12.4 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Herpes_UL14 PF03580.14 RUS90049.1 - 3.9 7.7 15.7 1.4 9.2 0.2 3.4 2 1 1 3 3 3 0 Herpesvirus UL14-like protein GlutR_dimer PF00745.20 RUS90049.1 - 7.3 7.1 10.1 3.6 8.1 2.5 3.0 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Stevor PF17410.2 RUS90049.1 - 9 5.7 9.2 0.19 11.3 1.0 2.1 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame NHL PF01436.21 RUS90051.1 - 9.8e-23 79.0 20.8 9.3e-06 25.4 0.2 6.5 7 0 0 7 7 7 4 NHL repeat DUF5128 PF17170.4 RUS90051.1 - 6.1e-12 45.3 0.5 6.9e-05 22.1 0.1 2.5 2 1 1 3 3 3 2 6-bladed beta-propeller SGL PF08450.12 RUS90051.1 - 6.6e-07 29.2 0.1 0.1 12.1 0.0 3.4 2 2 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF4934 PF16288.5 RUS90051.1 - 0.0002 21.2 0.3 0.13 12.2 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4934) TolB_like PF15869.5 RUS90051.1 - 0.0063 15.8 0.1 0.29 10.3 0.0 2.1 1 1 1 2 2 2 1 TolB-like 6-blade propeller-like Phytase-like PF13449.6 RUS90051.1 - 0.038 13.9 0.0 5.8 6.8 0.0 3.4 2 1 1 3 3 3 0 Esterase-like activity of phytase Lactonase PF10282.9 RUS90051.1 - 0.055 12.7 0.1 5.1 6.2 0.0 2.9 3 1 1 4 4 4 0 Lactonase, 7-bladed beta-propeller p450 PF00067.22 RUS90052.1 - 4.1e-12 45.6 0.0 4.6e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS90053.1 - 5.9e-36 124.2 0.0 6.5e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_Eps PF04627.13 RUS90054.1 - 5.6e-05 23.0 10.8 22 5.1 0.1 6.3 6 4 0 6 6 6 0 Mitochondrial ATP synthase epsilon chain TFA2_Winged_2 PF18121.1 RUS90054.1 - 0.00043 19.9 25.0 5.7 6.7 0.6 6.8 1 1 5 6 6 6 5 TFA2 Winged helix domain 2 YajC PF02699.15 RUS90054.1 - 0.00091 19.1 2.1 15 5.5 0.0 3.9 1 1 3 4 4 4 0 Preprotein translocase subunit SAD_SRA PF02182.17 RUS90054.1 - 0.013 15.2 3.0 11 5.7 0.6 3.8 1 1 2 3 3 3 0 SAD/SRA domain Sas6_CC PF18594.1 RUS90054.1 - 0.017 14.9 27.0 26 4.7 0.1 8.9 10 0 0 10 10 10 0 Sas6/XLF/XRCC4 coiled-coil domain ETF_alpha PF00766.19 RUS90054.1 - 0.02 14.9 1.8 56 3.9 0.1 3.8 1 1 3 4 4 4 0 Electron transfer flavoprotein FAD-binding domain zf-CCCH_6 PF18585.1 RUS90054.1 - 0.023 14.6 9.3 35 4.4 0.2 4.8 1 1 5 6 6 6 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Succ_CoA_lig PF13607.6 RUS90054.1 - 0.042 13.7 2.2 4.8 7.0 0.2 2.5 1 1 3 4 4 4 0 Succinyl-CoA ligase like flavodoxin domain UPF0228 PF05727.11 RUS90054.1 - 0.064 13.1 6.4 4.7 7.0 0.4 2.7 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0228) Mrpl_C PF18502.1 RUS90054.1 - 0.086 13.1 12.8 24 5.3 1.6 4.6 1 1 3 4 4 4 0 54S ribosomal protein L8 C-terminal domain ssDNA_TraI_N PF18272.1 RUS90054.1 - 0.15 12.1 13.8 58 3.8 0.1 5.5 1 1 2 5 5 5 0 single-stranded DNA binding TraI N-terminal subdomain DUF3221 PF11518.8 RUS90054.1 - 0.24 11.8 15.2 20 5.6 1.8 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3221) Zw10 PF06248.13 RUS90054.1 - 1.2 7.6 10.0 1.3 7.5 2.8 2.0 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 Peptidase_M24 PF00557.24 RUS90055.1 - 1e-22 80.9 0.5 1.4e-22 80.4 0.5 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF386 PF04074.12 RUS90055.1 - 0.0034 17.3 0.3 0.0075 16.2 0.3 1.5 1 0 0 1 1 1 1 YhcH/YjgK/YiaL HIM1 PF08732.10 RUS90055.1 - 0.048 13.2 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 HIM1 4HBT_2 PF13279.6 RUS90056.1 - 0.00067 20.1 0.0 0.69 10.4 0.0 2.4 2 1 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 RUS90056.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.3 1 1 0 1 1 1 0 Acyl-ACP thioesterase Acyl-ACP_TE PF01643.17 RUS90057.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 1 1 0 1 1 1 1 Acyl-ACP thioesterase SSF PF00474.17 RUS90059.1 - 1.6e-24 86.5 10.9 1.9e-24 86.3 10.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5056 PF16479.5 RUS90059.1 - 0.23 11.7 5.8 2.6 8.3 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) YwcE PF17368.2 RUS90060.1 - 0.0038 17.9 0.1 0.0077 16.9 0.1 1.5 1 0 0 1 1 1 1 Spore morphogenesis and germination YwcE Condensin2nSMC PF12422.8 RUS90061.1 - 1.4e-44 151.9 0.0 1.3e-43 148.7 0.0 2.3 2 1 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 RUS90061.1 - 3.6e-10 39.2 0.6 0.072 13.4 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 RUS90061.1 - 3.1e-06 27.5 2.8 0.019 15.3 0.1 3.8 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 RUS90061.1 - 5.4e-05 23.3 0.3 0.00017 21.7 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RUS90061.1 - 7.7e-05 21.4 0.1 0.00013 20.7 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 RUS90061.1 - 0.065 13.6 5.5 5.7 7.3 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 RUS90061.1 - 0.089 13.3 2.7 13 6.4 0.4 3.2 2 1 1 3 3 3 0 HEAT-like repeat DUF3517 PF12030.8 RUS90062.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Homeodomain PF00046.29 RUS90064.1 - 2.7e-20 71.9 4.2 2.7e-20 71.9 4.2 1.6 2 0 0 2 2 2 1 Homeodomain YdaS_antitoxin PF15943.5 RUS90064.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 RUS90064.1 - 0.37 10.3 0.1 0.37 10.3 0.1 2.6 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Zip PF02535.22 RUS90064.1 - 1.5 8.0 12.3 3 7.0 12.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Homeobox_KN PF05920.11 RUS90064.1 - 2.9 7.9 9.1 0.047 13.6 1.6 2.1 2 1 0 2 2 2 0 Homeobox KN domain Acyl-ACP_TE PF01643.17 RUS90066.1 - 9.4e-07 28.4 0.0 5.6e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 RUS90068.1 - 1.2e-06 29.0 0.0 0.00048 20.6 0.0 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 RUS90068.1 - 1.7e-05 24.2 0.0 3.4e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-ACP thioesterase FAD_binding_1 PF00667.20 RUS90069.1 - 8.1e-49 166.2 0.2 2.7e-48 164.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 RUS90069.1 - 9.8e-28 97.2 0.0 1.9e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RUS90069.1 - 5.7e-13 49.5 0.0 7.6e-10 39.4 0.0 3.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 RUS90069.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain HLH PF00010.26 RUS90070.1 - 1.2e-14 53.9 0.1 2.9e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CSRNP_N PF16019.5 RUS90070.1 - 0.0039 17.1 2.5 0.0039 17.1 2.5 1.5 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus SPATA48 PF15073.6 RUS90070.1 - 0.28 11.5 4.7 0.11 12.8 1.1 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 ASC PF00858.24 RUS90071.1 - 9.6e-35 120.4 0.8 1.2e-33 116.8 0.8 2.1 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel YEATS PF03366.16 RUS90072.1 - 5.2e-24 84.0 0.2 1.2e-23 82.9 0.2 1.6 1 0 0 1 1 1 1 YEATS family SecA_SW PF07516.13 RUS90072.1 - 0.00051 20.2 0.7 0.001 19.2 0.7 1.4 1 0 0 1 1 1 1 SecA Wing and Scaffold domain EF-hand_7 PF13499.6 RUS90073.1 - 2.5e-07 31.0 3.1 4.3e-06 27.1 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS90073.1 - 5.6e-07 29.3 0.5 6.7e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS90073.1 - 3.7e-05 23.3 4.3 0.0023 17.7 0.1 3.5 1 1 2 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 RUS90073.1 - 0.0012 18.6 1.2 0.85 9.5 0.1 2.8 2 2 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 RUS90073.1 - 0.0014 18.0 2.5 0.014 14.9 0.1 3.0 3 0 0 3 3 3 1 EF hand DUF4937 PF16291.5 RUS90073.1 - 0.015 15.5 0.4 0.038 14.2 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4937 Cys_rich_CPCC PF14206.6 RUS90073.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC CNP_C_terminal PF17839.1 RUS90073.1 - 0.092 13.5 0.2 0.19 12.4 0.2 1.6 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase VWC PF00093.18 RUS90074.1 - 1.5e-11 44.5 33.0 9.7e-06 25.8 12.6 2.1 2 0 0 2 2 2 2 von Willebrand factor type C domain Tudor_2 PF18104.1 RUS90074.1 - 0.086 12.5 0.6 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Metallothio_6 PF05522.11 RUS90074.1 - 3.5 8.2 32.9 1.4 9.5 10.0 2.4 2 0 0 2 2 2 0 Metallothionein MFS_1 PF07690.16 RUS90075.1 - 3.8e-10 39.2 37.1 3.8e-10 39.2 37.1 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_14 PF03647.13 RUS90075.1 - 5.4 7.8 9.8 0.29 11.9 1.2 3.0 3 0 0 3 3 3 0 Transmembrane proteins 14C PEX11 PF05648.14 RUS90076.1 - 2.7e-45 154.6 0.1 3.1e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Nop14 PF04147.12 RUS90077.1 - 6.6e-05 21.4 1.8 7.6e-05 21.1 1.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 RUS90077.1 - 0.0087 15.2 9.7 0.013 14.7 9.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 RUS90077.1 - 0.026 12.8 2.7 0.024 12.9 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS90077.1 - 0.038 13.3 9.2 0.054 12.8 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.6 RUS90077.1 - 0.039 14.3 5.9 0.083 13.3 5.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 BUD22 PF09073.10 RUS90077.1 - 0.044 13.1 2.0 0.047 13.0 2.0 1.1 1 0 0 1 1 1 0 BUD22 DUF3295 PF11702.8 RUS90077.1 - 0.046 13.1 3.1 0.06 12.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PPP4R2 PF09184.11 RUS90077.1 - 0.19 11.3 3.9 0.26 10.8 3.9 1.2 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 RUS90077.1 - 0.25 9.9 3.9 0.29 9.7 3.9 1.2 1 0 0 1 1 1 0 Utp14 protein CENP-B_dimeris PF09026.10 RUS90077.1 - 0.48 10.8 14.0 0.84 10.1 14.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 RUS90077.1 - 0.62 8.5 5.8 0.73 8.3 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 RUS90077.1 - 0.62 8.4 7.8 0.69 8.3 7.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 RUS90077.1 - 2.7 6.0 11.5 3.4 5.7 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi 2-ph_phosp PF04029.14 RUS90078.1 - 0.15 11.3 2.3 0.24 10.5 2.3 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase RIBIOP_C PF04950.12 RUS90079.1 - 1.4e-88 297.1 2.5 1.4e-88 297.1 2.5 3.3 5 1 1 6 6 5 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RUS90079.1 - 1.5e-33 114.7 0.0 7.7e-33 112.4 0.0 2.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 RUS90079.1 - 9.1e-07 28.6 0.0 0.00021 20.9 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RUS90079.1 - 0.00045 20.5 0.1 0.044 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RUS90079.1 - 0.00071 19.6 0.2 0.00071 19.6 0.2 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 RUS90079.1 - 0.012 16.0 0.0 0.046 14.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 RUS90079.1 - 0.018 14.6 0.4 0.067 12.7 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 RUS90079.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 RUS90079.1 - 0.046 13.8 0.1 0.21 11.6 0.1 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RUS90079.1 - 0.065 13.7 0.0 0.065 13.7 0.0 2.7 3 0 0 3 3 3 0 ABC transporter AAA PF00004.29 RUS90079.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UCH PF00443.29 RUS90080.1 - 2.8e-38 131.9 0.3 3.5e-38 131.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS90080.1 - 6.9e-07 29.2 0.7 3.7e-06 26.8 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Desulfoferrod_N PF06397.12 RUS90081.1 - 0.0057 16.3 0.3 0.011 15.4 0.3 1.4 1 0 0 1 1 1 1 Desulfoferrodoxin, N-terminal domain zf-C2H2_2 PF12756.7 RUS90081.1 - 0.0065 16.8 1.3 0.0084 16.4 1.3 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 RUS90081.1 - 0.18 12.1 3.5 0.29 11.5 3.5 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M24 PF00557.24 RUS90082.1 - 8.6e-50 169.3 0.3 1.1e-49 169.0 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 RUS90082.1 - 2.2e-20 72.6 5.4 4.5e-20 71.7 5.4 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 RUS90082.1 - 0.00034 20.6 2.0 0.00087 19.3 2.0 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RUS90082.1 - 0.12 12.3 3.7 0.24 11.3 3.7 1.6 1 0 0 1 1 1 0 HIT zinc finger RNase_Zc3h12a PF11977.8 RUS90082.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain TK PF00265.18 RUS90083.1 - 2.3e-64 216.5 0.1 2.9e-64 216.2 0.1 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 RUS90083.1 - 0.00076 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RUS90083.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BLOC1_2 PF10046.9 RUS90084.1 - 3.6e-36 123.3 4.0 5.1e-36 122.9 4.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.9 RUS90084.1 - 0.0044 16.5 0.2 0.0046 16.4 0.2 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF948 PF06103.11 RUS90084.1 - 0.0069 16.6 0.1 0.017 15.3 0.1 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 RUS90084.1 - 0.0071 16.5 1.2 0.0097 16.1 1.2 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 RUS90084.1 - 0.037 14.1 0.2 0.048 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med9 PF07544.13 RUS90084.1 - 0.043 13.9 0.6 0.081 13.0 0.6 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 XhlA PF10779.9 RUS90084.1 - 0.043 14.0 0.6 0.18 12.0 0.1 2.2 1 1 2 3 3 3 0 Haemolysin XhlA DUF1759 PF03564.15 RUS90084.1 - 0.054 13.4 0.5 0.074 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4164 PF13747.6 RUS90084.1 - 0.12 12.7 0.4 7.1 7.0 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DASH_Dam1 PF08653.10 RUS90084.1 - 0.17 11.7 0.1 0.78 9.6 0.0 2.0 1 1 2 3 3 3 0 DASH complex subunit Dam1 CENP-Q PF13094.6 RUS90084.1 - 0.33 11.1 4.2 0.47 10.6 3.4 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit JIP_LZII PF16471.5 RUS90084.1 - 0.35 11.1 1.7 0.8 9.9 0.3 2.2 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II UPF0449 PF15136.6 RUS90084.1 - 0.64 10.5 3.5 1.2 9.6 3.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Peptidase_S10 PF00450.22 RUS90085.1 - 4.3e-83 280.0 0.3 5.2e-83 279.8 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 RUS90085.1 - 0.06 12.6 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pentaxin PF00354.17 RUS90086.1 - 1e-17 64.5 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 RUS90086.1 - 1.1e-16 61.3 0.2 1.6e-16 60.8 0.2 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily HRM PF02793.22 RUS90086.1 - 0.0012 19.1 1.6 0.0023 18.2 0.2 2.3 2 0 0 2 2 2 1 Hormone receptor domain TIL PF01826.17 RUS90086.1 - 3.5 8.0 9.1 0.6 10.4 0.5 2.6 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain 7tm_2 PF00002.24 RUS90087.1 - 1.5e-28 99.7 18.8 2.2e-28 99.2 18.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 RUS90087.1 - 4.9e-08 32.6 0.2 1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Herpes_capsid PF06112.11 RUS90087.1 - 0.16 12.0 2.0 0.31 11.1 2.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GPS PF01825.21 RUS90087.1 - 0.39 11.3 2.6 0.27 11.8 0.2 2.0 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif zf-C2H2_4 PF13894.6 RUS90089.1 - 5.6e-10 39.2 17.1 0.007 17.1 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS90089.1 - 8.2e-10 38.6 20.3 0.0012 19.1 4.3 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type CpXC PF14353.6 RUS90089.1 - 0.00078 19.5 3.4 0.33 11.0 0.7 2.7 2 1 0 2 2 2 2 CpXC protein zf-C2H2_2 PF12756.7 RUS90089.1 - 0.0055 17.0 10.8 1.1 9.6 0.7 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RUS90089.1 - 0.028 14.4 14.5 0.044 13.8 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 RUS90089.1 - 0.035 14.1 13.0 0.36 10.9 1.3 3.6 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 RUS90089.1 - 0.036 14.5 1.7 0.036 14.5 1.7 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_12 PF11331.8 RUS90089.1 - 0.068 13.0 0.6 6.9 6.6 0.4 3.1 2 1 1 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_9 PF14369.6 RUS90089.1 - 0.07 13.4 3.2 1.9 8.8 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon Prok-RING_1 PF14446.6 RUS90089.1 - 0.15 12.0 1.4 58 3.7 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 RUS90089.1 - 0.18 11.8 5.7 1.3 9.1 0.5 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 RUS90089.1 - 0.24 11.5 4.7 6.2 7.0 0.0 3.2 2 1 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 RUS90089.1 - 0.37 10.4 2.9 4.2 7.0 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_5 PF13719.6 RUS90089.1 - 0.7 9.7 4.9 32 4.4 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 RUS90089.1 - 8.2 6.8 14.3 9.9 6.6 1.5 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RNase_PH PF01138.21 RUS90090.1 - 6e-19 68.8 0.2 6e-19 68.8 0.2 1.8 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS90090.1 - 0.0021 18.0 0.1 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Prefoldin_2 PF01920.20 RUS90091.1 - 2.6e-05 24.1 3.6 4.3e-05 23.4 3.6 1.4 1 1 0 1 1 1 1 Prefoldin subunit IL13 PF03487.13 RUS90091.1 - 0.0013 18.5 0.3 0.0021 17.8 0.2 1.4 1 1 0 1 1 1 1 Interleukin-13 Thioredoxin_14 PF18402.1 RUS90091.1 - 0.04 13.9 0.1 0.043 13.8 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain NAD_binding_2 PF03446.15 RUS90091.1 - 0.084 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MYO10_CC PF16735.5 RUS90091.1 - 1.9 8.7 8.1 3 8.0 0.9 3.1 2 1 1 3 3 3 0 Unconventional myosin-X coiled coil domain p450 PF00067.22 RUS90092.1 - 1.8e-80 271.0 3.4 8.7e-63 212.6 0.7 2.1 2 0 0 2 2 2 2 Cytochrome P450 SIR2 PF02146.17 RUS90093.1 - 2.9e-65 219.5 0.0 6.8e-65 218.3 0.0 1.6 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.13 RUS90093.1 - 0.00093 19.0 0.2 0.0019 18.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 RUS90093.1 - 0.0024 17.6 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Pes-10 PF07149.11 RUS90093.1 - 7.3 5.5 15.4 12 4.9 15.4 1.3 1 0 0 1 1 1 0 Pes-10 DnaJ PF00226.31 RUS90094.1 - 7.8e-19 67.6 1.9 1.4e-18 66.7 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydro_lipase PF04083.16 RUS90097.1 - 6.6e-21 73.6 0.0 1.2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 RUS90097.1 - 7.3e-19 68.4 0.3 1.1e-18 67.8 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RUS90097.1 - 1.5e-08 34.2 0.0 3.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 RUS90097.1 - 0.015 14.9 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Cutinase PF01083.22 RUS90097.1 - 0.059 13.3 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.14 RUS90097.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Astacin PF01400.24 RUS90099.1 - 3.9e-34 117.9 0.2 5.2e-34 117.5 0.2 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Sushi PF00084.20 RUS90099.1 - 1e-11 45.2 1.0 3e-11 43.7 1.0 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) MAM PF00629.23 RUS90099.1 - 1.6e-09 37.9 0.5 2.5e-09 37.3 0.5 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu HRM PF02793.22 RUS90099.1 - 0.048 14.0 0.8 0.14 12.5 0.1 2.1 2 1 0 2 2 2 0 Hormone receptor domain Peptidase_M10 PF00413.24 RUS90099.1 - 0.092 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Matrixin MAM PF00629.23 RUS90100.1 - 1.3e-40 139.0 0.1 4.2e-29 101.5 0.2 2.0 2 0 0 2 2 2 2 MAM domain, meprin/A5/mu DUF3400 PF11880.8 RUS90100.1 - 0.89 9.1 2.8 28 4.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3400) MAM PF00629.23 RUS90101.1 - 4.6e-37 127.4 0.4 5.2e-37 127.2 0.4 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF2278 PF10042.9 RUS90101.1 - 0.069 13.2 0.0 13 5.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) MFS_1 PF07690.16 RUS90102.1 - 5.6e-39 134.1 38.0 6.7e-22 77.9 7.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RUS90102.1 - 9.1e-06 24.8 18.6 2.9e-05 23.1 0.0 2.6 2 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 RUS90102.1 - 1.6e-05 24.0 5.9 1.6e-05 24.0 5.9 3.4 2 2 0 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 RUS90102.1 - 7.6e-05 22.2 10.9 7.6e-05 22.2 10.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SAND PF01342.21 RUS90104.1 - 3e-24 84.5 0.3 5.2e-24 83.7 0.3 1.4 1 0 0 1 1 1 1 SAND domain HECT PF00632.25 RUS90106.1 - 1e-96 324.1 0.0 1.7e-96 323.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 RUS90106.1 - 2.4e-17 62.7 5.7 4.3e-09 36.3 0.6 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.30 RUS90106.1 - 2e-16 60.2 0.0 4.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Lipase_3 PF01764.25 RUS90108.1 - 3.1e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) HGTP_anticodon PF03129.20 RUS90110.1 - 8e-12 45.1 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain Sugarporin_N PF11471.8 RUS90110.1 - 0.049 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ER_lumen_recept PF00810.18 RUS90111.1 - 4.8e-56 189.7 9.2 4.8e-56 189.7 9.2 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor Parvo_NS1 PF01057.17 RUS90112.1 - 0.074 12.1 0.0 0.086 11.9 0.0 1.0 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Brix PF04427.18 RUS90113.1 - 7e-43 147.0 5.3 2.6e-36 125.5 2.0 2.4 1 1 1 2 2 2 2 Brix domain COPIIcoated_ERV PF07970.12 RUS90113.1 - 0.083 12.7 0.2 0.083 12.7 0.2 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum vesicle transporter DNA_pol_B_palm PF14792.6 RUS90114.1 - 8.6e-36 122.6 0.0 1.5e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 RUS90114.1 - 6.5e-21 73.9 0.0 1.1e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 RUS90114.1 - 2e-19 69.5 0.0 3.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 RUS90114.1 - 3.3e-19 69.0 3.8 2.5e-17 63.0 0.4 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH_5 PF14520.6 RUS90114.1 - 9.7e-08 32.5 0.8 0.00016 22.2 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 RUS90114.1 - 4.2e-05 23.5 0.4 0.085 13.0 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif Cdd1 PF11731.8 RUS90114.1 - 0.00036 20.7 0.1 0.0075 16.5 0.0 2.9 2 1 1 3 3 3 1 Pathogenicity locus HHH_3 PF12836.7 RUS90114.1 - 0.00067 19.9 0.2 1.9 8.8 0.0 2.8 2 1 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 RUS90114.1 - 0.0014 18.3 1.1 0.33 10.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.23 RUS90114.1 - 0.034 14.4 0.0 0.097 13.0 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.8 RUS90114.1 - 0.054 13.8 0.2 5 7.7 0.0 3.0 2 0 0 2 2 2 0 IMS family HHH motif LRR_8 PF13855.6 RUS90115.1 - 9.6e-18 63.7 22.0 7.8e-08 32.0 6.6 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS90115.1 - 9e-11 41.8 10.7 0.00038 20.8 1.8 4.3 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS90115.1 - 0.00016 21.2 6.2 0.0042 16.6 0.6 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RUS90115.1 - 0.0013 19.0 11.0 6 7.8 0.1 5.1 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS90115.1 - 0.38 10.9 15.2 2.9 8.2 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Guanylate_cyc PF00211.20 RUS90116.1 - 3.6e-64 215.7 0.0 6.2e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 RUS90116.1 - 5.3e-36 124.2 0.0 9.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS90116.1 - 8e-29 100.8 0.1 6.6e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain ANF_receptor PF01094.28 RUS90116.1 - 1.7e-06 27.4 0.0 3.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region HNOBA PF07701.14 RUS90116.1 - 7.4e-06 25.6 1.1 1.4e-05 24.7 1.1 1.4 1 0 0 1 1 1 1 Heme NO binding associated fn3_4 PF16794.5 RUS90116.1 - 0.064 13.2 0.1 8.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Fibronectin-III type domain 7tm_1 PF00001.21 RUS90118.1 - 1.8e-06 27.5 16.8 5.1e-06 26.0 16.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CCSMST1 PF15013.6 RUS90118.1 - 0.016 15.4 0.7 0.016 15.4 0.7 1.8 2 0 0 2 2 2 0 CCSMST1 family 7TM_GPCR_Srw PF10324.9 RUS90118.1 - 4.3 6.5 20.5 3.3 6.9 1.3 2.4 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw RabGAP-TBC PF00566.18 RUS90119.1 - 4.5e-12 46.1 0.7 5.2e-12 45.9 0.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mhr1 PF12829.7 RUS90120.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Glycos_transf_2 PF00535.26 RUS90121.1 - 1.3e-21 77.2 0.0 1.8e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RUS90121.1 - 2.9e-05 24.1 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RUS90121.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RUS90122.1 - 4.9e-35 120.8 0.0 1.1e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 RUS90122.1 - 1.9e-25 89.5 0.0 3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RUS90122.1 - 9.3e-06 25.2 0.1 2.5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 RUS90122.1 - 0.001 19.0 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RUS90122.1 - 0.042 13.3 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 zf-Tim10_DDP PF02953.15 RUS90123.1 - 7.3e-21 73.6 2.4 9.3e-21 73.3 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 RUS90123.1 - 0.034 13.9 2.2 0.25 11.0 2.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DDE_1 PF03184.19 RUS90124.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DEAD PF00270.29 RUS90125.1 - 1e-18 67.7 0.0 1.9e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS90125.1 - 1.8e-14 54.0 0.0 7.4e-12 45.6 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RUS90125.1 - 3e-08 34.3 4.7 1.2e-07 32.3 4.7 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 RUS90125.1 - 7.5e-06 26.0 0.0 3.2e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIS_M PF07500.14 RUS90125.1 - 0.71 10.4 7.0 0.29 11.6 1.0 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain zf-AN1 PF01428.16 RUS90126.1 - 3e-25 88.1 29.2 2.6e-13 49.9 4.6 2.8 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 RUS90126.1 - 2e-05 24.9 19.3 0.013 15.9 4.9 2.6 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain UIM PF02809.20 RUS90126.1 - 0.02 14.8 3.8 0.02 14.8 3.8 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif C1_4 PF07975.12 RUS90126.1 - 0.18 12.1 21.3 0.44 10.8 6.8 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain MG1 PF17790.1 RUS90128.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG1 MG2 PF01835.19 RUS90128.1 - 0.13 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 MG2 domain A2M PF00207.22 RUS90129.1 - 6.5e-22 77.2 0.4 3.1e-21 75.0 0.1 2.4 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 RUS90129.1 - 4.2e-21 75.7 0.2 9.8e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 RUS90129.1 - 1.5e-11 44.4 0.0 4.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 RUS90129.1 - 1.6e-05 25.0 0.1 0.022 14.9 0.0 4.0 3 1 1 4 4 4 1 Macroglobulin domain MG4 TED_complement PF07678.14 RUS90130.1 - 1.4e-76 257.5 0.1 1.8e-76 257.2 0.1 1.1 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 RUS90130.1 - 2.8e-12 47.2 1.1 3.1e-11 43.8 0.0 2.8 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain SQHop_cyclase_C PF13243.6 RUS90130.1 - 0.037 13.1 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain CH PF00307.31 RUS90131.1 - 9.6e-23 80.5 0.0 1.2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 RUS90131.1 - 1.7e-12 46.7 4.2 1.7e-12 46.7 4.2 2.6 3 0 0 3 3 3 1 Calponin family repeat CDC24 PF06395.11 RUS90131.1 - 0.0031 17.7 0.1 0.0044 17.2 0.1 1.2 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 RUS90131.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 CAMSAP CH domain RNA_pol_A_CTD PF03118.15 RUS90132.1 - 0.011 15.5 1.8 6.6 6.6 0.0 4.4 1 1 3 4 4 4 0 Bacterial RNA polymerase, alpha chain C terminal domain AF-4 PF05110.13 RUS90133.1 - 0.27 9.3 34.7 0.32 9.0 34.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOBP PF15279.6 RUS90133.1 - 2.2 8.8 14.0 3 8.4 14.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MmoB_DmpM PF02406.17 RUS90134.1 - 0.00047 20.3 5.7 4.9 7.4 0.0 5.6 3 1 4 7 7 7 1 MmoB/DmpM family DUF150 PF02576.17 RUS90134.1 - 0.0037 17.6 3.2 23 5.5 0.0 5.4 3 2 3 6 6 6 1 RimP N-terminal domain SWC7 PF17330.2 RUS90134.1 - 0.36 10.9 4.5 9.4 6.4 0.1 4.1 1 1 3 5 5 5 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 HMG_box PF00505.19 RUS90135.1 - 2.1e-27 95.3 3.5 4.2e-27 94.4 3.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS90135.1 - 9.8e-12 45.3 2.2 2.5e-11 44.0 2.2 1.8 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 RUS90135.1 - 1.7e-11 45.0 9.9 1.7e-11 45.0 9.9 5.0 2 1 1 4 4 4 1 SOX transcription factor SNF PF00209.18 RUS90136.1 - 1.7e-61 208.6 10.0 1.9e-61 208.4 10.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ERG4_ERG24 PF01222.17 RUS90137.1 - 3.3e-72 243.6 20.8 3.9e-72 243.4 20.8 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Chloroa_b-bind PF00504.21 RUS90137.1 - 0.07 13.7 0.2 4.9 7.7 0.0 2.8 2 1 1 3 3 3 0 Chlorophyll A-B binding protein SMC_N PF02463.19 RUS90138.1 - 2.3e-24 86.1 0.0 4.3e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RUS90138.1 - 1.3e-10 41.6 0.0 1.3e-10 41.6 0.0 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 RUS90138.1 - 1.6e-09 38.6 22.1 1.6e-09 38.6 22.1 5.1 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 RUS90138.1 - 1.4e-05 25.1 3.2 0.0035 17.2 0.4 2.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Diphtheria_R PF01324.19 RUS90138.1 - 5.6e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Diphtheria toxin, R domain AAA_29 PF13555.6 RUS90138.1 - 0.0028 17.4 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 RUS90138.1 - 0.0039 16.8 21.7 0.0039 16.8 21.7 4.0 3 1 0 3 3 3 2 Mechanosensitive ion channel porin domain APG6_N PF17675.1 RUS90138.1 - 0.0046 17.5 16.6 0.0046 17.5 16.6 6.1 2 2 3 5 5 5 1 Apg6 coiled-coil region ABC_tran PF00005.27 RUS90138.1 - 0.071 13.6 0.3 0.071 13.6 0.3 5.2 3 2 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 RUS90138.1 - 0.45 9.8 7.3 1.3 8.3 0.1 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family SBP_bac_3 PF00497.20 RUS90139.1 - 4.8e-52 176.6 0.0 1.8e-17 63.5 0.0 4.4 3 2 0 3 3 3 3 Bacterial extracellular solute-binding proteins, family 3 Rbx_binding PF18113.1 RUS90139.1 - 1.1e-05 25.1 0.0 2.6 7.9 0.0 3.5 3 0 0 3 3 3 3 Rubredoxin binding C-terminal domain Herpes_UL1 PF05259.11 RUS90139.1 - 0.019 15.1 0.1 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus glycoprotein L Peptidase_C23 PF05379.11 RUS90139.1 - 0.021 15.0 0.0 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Carlavirus endopeptidase Lig_chan-Glu_bd PF10613.9 RUS90139.1 - 0.051 13.8 0.4 39 4.5 0.0 4.0 5 1 0 5 5 5 0 Ligated ion channel L-glutamate- and glycine-binding site PADR1 PF08063.12 RUS90139.1 - 0.29 10.9 5.4 14 5.5 0.1 4.0 3 1 0 3 3 3 0 PADR1 (NUC008) domain SBP_bac_3 PF00497.20 RUS90140.1 - 8.3e-33 113.7 0.0 2.9e-15 56.3 0.0 3.1 2 2 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 DUF4407 PF14362.6 RUS90144.1 - 1.8 7.8 9.5 0.35 10.2 3.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) CP2 PF04516.15 RUS90145.1 - 2.3e-54 184.2 0.8 3.7e-54 183.5 0.8 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phytochelatin PF05023.14 RUS90145.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Phytochelatin synthase Clat_adaptor_s PF01217.20 RUS90146.1 - 8.3e-57 191.1 0.9 9.7e-57 190.9 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 RUS90146.1 - 0.0013 17.4 0.1 0.0015 17.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) SCAN PF02023.17 RUS90147.1 - 4.6e-15 55.2 0.9 1.4e-14 53.7 0.2 2.1 2 0 0 2 2 2 1 SCAN domain RVT_1 PF00078.27 RUS90147.1 - 6.9e-14 51.9 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 RUS90147.1 - 0.00015 21.7 9.7 0.0014 18.6 0.5 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 RUS90147.1 - 4.2 7.1 12.6 3.1 7.6 2.6 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger MOSC_N PF03476.16 RUS90148.1 - 3.8e-23 81.6 0.0 5.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 RUS90148.1 - 1.7e-19 70.2 0.0 3.6e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 MOSC domain Gram_pos_anchor PF00746.21 RUS90148.1 - 0.019 14.9 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4010 PF13194.6 RUS90148.1 - 0.091 12.4 0.0 4.8 6.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Tektin PF03148.14 RUS90149.1 - 6.9e-137 456.3 37.9 7.9e-137 456.1 37.9 1.0 1 0 0 1 1 1 1 Tektin family IL17 PF06083.11 RUS90149.1 - 0.089 13.3 0.1 0.33 11.4 0.1 2.0 1 0 0 1 1 1 0 Interleukin-17 Med29 PF11568.8 RUS90149.1 - 0.18 12.0 6.0 0.85 9.8 0.2 2.7 2 1 0 2 2 2 0 Mediator complex subunit 29 DUF1664 PF07889.12 RUS90149.1 - 0.64 10.1 16.4 1.2 9.2 1.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 RUS90149.1 - 3 7.9 7.9 9.2 6.3 0.0 3.5 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nas2_N PF18265.1 RUS90149.1 - 9.4 6.2 11.5 11 6.0 0.1 4.1 4 0 0 4 4 4 0 Nas2 N_terminal domain POP1 PF06978.11 RUS90150.1 - 1.9e-35 122.8 18.2 1.3e-20 74.3 1.4 2.9 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 RUS90150.1 - 3.9e-26 91.2 0.0 1.7e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 RUS90150.1 - 4.2e-05 23.0 0.0 1.2 8.4 0.0 3.2 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Lipoprot_C PF08794.10 RUS90150.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like GNT-I PF03071.15 RUS90151.1 - 1.3e-47 162.5 0.8 9.9e-47 159.7 0.8 1.9 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 RUS90151.1 - 1.6e-25 89.4 0.1 4.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Interleukin-like EMT inducer MGAT2 PF05060.14 RUS90151.1 - 0.0033 16.5 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyltransferase II (MGAT2) CABIT PF12736.7 RUS90152.1 - 1e-36 126.7 0.1 1e-35 123.4 0.1 2.1 1 1 0 1 1 1 1 Cell-cycle sustaining, positive selection, Ribosomal_S7e PF01251.18 RUS90153.1 - 8.7e-46 156.0 0.9 9.7e-46 155.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e 7TM_GPCR_Srx PF10328.9 RUS90154.1 - 2e-08 34.2 16.8 2e-08 34.2 16.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS90154.1 - 7.6e-07 28.8 21.7 1.9e-06 27.5 21.7 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 RUS90154.1 - 1.7e-05 24.3 20.5 2e-05 24.1 20.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1030 PF06270.11 RUS90154.1 - 0.011 15.5 0.7 0.035 13.8 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) UCR_TM PF02921.14 RUS90154.1 - 0.13 12.7 0.4 4.8 7.7 0.0 2.8 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region SHR3_chaperone PF08229.11 RUS90154.1 - 0.15 11.1 3.4 1.8 7.5 0.3 2.5 2 0 0 2 2 2 0 ER membrane protein SH3 ECSCR PF15820.5 RUS90154.1 - 0.71 9.7 7.2 0.65 9.8 0.6 3.2 4 0 0 4 4 4 0 Endothelial cell-specific chemotaxis regulator 7tm_1 PF00001.21 RUS90155.1 - 8.7e-12 44.9 4.1 1.4e-11 44.3 4.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS90155.1 - 5.7e-05 22.9 15.6 0.00013 21.7 15.6 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Sugar_tr PF00083.24 RUS90156.1 - 5.6e-21 74.9 7.1 7.1e-21 74.6 7.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS90156.1 - 3e-12 46.2 11.8 3e-12 46.2 11.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 RUS90157.1 - 6.5e-06 25.3 5.0 1.3e-05 24.3 5.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS90157.1 - 0.0056 15.6 6.2 0.0066 15.4 6.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Striatin PF08232.12 RUS90159.1 - 0.0076 16.9 0.6 0.011 16.3 0.6 1.2 1 0 0 1 1 1 1 Striatin family DUF4820 PF16091.5 RUS90159.1 - 0.3 10.4 3.1 0.39 10.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TIMELESS PF04821.14 RUS90160.1 - 7.2e-21 74.7 0.2 2.6e-20 72.9 0.2 1.9 1 1 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 RUS90160.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Timeless protein C terminal region CBS PF00571.28 RUS90160.1 - 0.21 12.0 0.3 3 8.4 0.0 2.6 2 0 0 2 2 2 0 CBS domain Glyco_hydro_39 PF01229.17 RUS90161.1 - 4.1e-81 273.0 0.0 7.2e-81 272.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Integrase_H2C2 PF17921.1 RUS90162.1 - 2.5e-08 33.9 1.7 4.7e-08 33.0 1.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 RUS90162.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Bd3614-deam PF14439.6 RUS90162.1 - 0.021 14.9 0.3 0.049 13.7 0.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase ATG11 PF10377.9 RUS90162.1 - 0.039 14.0 0.2 0.056 13.5 0.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 Ald_Xan_dh_C2 PF02738.18 RUS90162.1 - 0.071 11.6 0.0 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase FAM101 PF15068.6 RUS90163.1 - 3.5e-14 53.3 2.1 6.1e-14 52.5 2.1 1.4 1 0 0 1 1 1 1 FAM101 family Trypsin_2 PF13365.6 RUS90164.1 - 0.0044 17.9 0.1 0.016 16.1 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Glyco_transf_21 PF13506.6 RUS90165.1 - 5.7e-46 156.1 0.0 7.5e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RUS90165.1 - 2.5e-19 70.1 0.0 3.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RUS90165.1 - 8.8e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 WIF PF02019.18 RUS90166.1 - 4.1e-26 91.2 0.2 4.6e-26 91.1 0.2 1.0 1 0 0 1 1 1 1 WIF domain LMBR1 PF04791.16 RUS90167.1 - 4.8e-06 25.8 0.8 6.8e-06 25.3 0.8 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein YL1 PF05764.13 RUS90167.1 - 0.02 15.0 55.9 0.038 14.1 55.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF262 PF03235.14 RUS90167.1 - 0.58 10.3 16.1 0.81 9.8 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 CDC45 PF02724.14 RUS90167.1 - 1.4 7.1 41.8 1.9 6.7 41.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 RUS90167.1 - 7.3 6.8 51.2 13 6.0 51.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) LRR_8 PF13855.6 RUS90168.1 - 5.6e-53 176.6 48.7 1.8e-09 37.2 0.1 11.1 8 2 3 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 RUS90168.1 - 5.7e-46 153.7 62.8 2e-05 24.8 0.9 13.1 8 4 3 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS90168.1 - 2e-15 55.0 37.3 9.7 7.2 0.4 19.8 22 1 0 22 22 22 1 Leucine Rich Repeat LRR_9 PF14580.6 RUS90168.1 - 4.9e-10 39.2 31.0 0.0019 17.7 0.5 7.4 4 3 4 8 8 8 6 Leucine-rich repeat LRR_6 PF13516.6 RUS90168.1 - 9.4e-06 25.3 60.0 0.64 10.2 0.1 16.6 19 0 0 19 19 19 4 Leucine Rich repeat DUF5568 PF17724.1 RUS90168.1 - 0.39 10.5 2.4 24 4.7 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5568) NKWYS PF10364.9 RUS90168.1 - 2.4 8.3 4.7 2.5 8.2 0.5 2.9 2 1 0 2 2 2 0 Putative capsular polysaccharide synthesis protein HECT PF00632.25 RUS90169.1 - 8.9e-85 284.8 0.2 2.7e-84 283.3 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 RUS90169.1 - 9.5e-18 64.6 0.1 1.9e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 WWE domain LCD1 PF09798.9 RUS90169.1 - 0.041 12.4 2.8 0.097 11.2 2.2 1.9 2 0 0 2 2 2 0 DNA damage checkpoint protein HEAT_2 PF13646.6 RUS90169.1 - 0.1 13.0 0.0 0.47 10.9 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats RIX1 PF08167.12 RUS90169.1 - 0.1 12.3 1.7 0.42 10.3 0.5 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Arm PF00514.23 RUS90169.1 - 0.13 12.4 0.0 6.4 7.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PuR_N PF09182.10 RUS90170.1 - 0.15 12.0 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal FUN14 PF04930.15 RUS90171.1 - 4.4e-21 75.1 3.4 6.2e-21 74.6 3.4 1.2 1 0 0 1 1 1 1 FUN14 family SPC12 PF06645.13 RUS90171.1 - 0.31 11.2 4.0 0.24 11.5 0.7 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 RUS90172.1 - 1.3e-20 73.6 42.1 3.1e-10 39.5 11.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 RUS90172.1 - 1.5 8.3 18.3 0.4 10.2 4.6 3.3 3 0 0 3 3 3 0 ABC-2 family transporter protein TSP_1 PF00090.19 RUS90173.1 - 4.3e-14 52.4 19.1 1.9e-10 40.8 11.6 3.2 3 1 0 3 3 3 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 RUS90173.1 - 6.1e-08 32.7 6.3 6.1e-08 32.7 6.3 3.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A EphA2_TM PF14575.6 RUS90173.1 - 0.014 16.2 0.0 0.04 14.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain COX6A PF02046.15 RUS90174.1 - 2.7e-06 27.8 2.7 4.1e-06 27.2 2.6 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa ABC2_membrane_4 PF12730.7 RUS90174.1 - 0.015 15.2 0.2 0.021 14.8 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ig PF00047.25 RUS90175.1 - 5.5e-05 23.3 0.2 0.00014 22.0 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS90175.1 - 0.011 15.8 0.7 0.075 13.1 0.5 2.2 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 RUS90175.1 - 0.024 15.2 0.0 0.041 14.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 RUS90175.1 - 0.062 13.6 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain PgaD PF13994.6 RUS90175.1 - 0.26 11.3 1.7 0.43 10.6 1.7 1.3 1 0 0 1 1 1 0 PgaD-like protein Lectin_C PF00059.21 RUS90176.1 - 1.9e-07 31.7 0.0 5.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Lectin C-type domain Arylsulfotran_2 PF14269.6 RUS90176.1 - 0.042 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Lectin_C PF00059.21 RUS90178.1 - 3.4e-18 66.3 0.1 5e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain HAS-barrel PF09378.10 RUS90180.1 - 0.073 13.2 0.0 45 4.3 0.0 3.7 3 1 1 4 4 4 0 HAS barrel domain adh_short PF00106.25 RUS90181.1 - 3.8e-36 124.4 0.2 4.3e-36 124.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS90181.1 - 2.3e-26 92.8 0.2 2.7e-26 92.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS90181.1 - 3.1e-08 33.7 0.1 4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 KR domain RNA_polI_A34 PF08208.11 RUS90182.1 - 0.98 9.5 25.0 1.6 8.8 25.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ctr PF04145.15 RUS90182.1 - 4 8.0 0.0 4 8.0 0.0 2.7 2 1 0 2 2 2 0 Ctr copper transporter family TSGP1 PF07771.11 RUS90182.1 - 8 6.6 15.6 17 5.6 15.6 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 ABA_GPCR PF12430.8 RUS90183.1 - 1.5e-39 135.7 8.7 1.5e-39 135.7 8.7 3.0 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RUS90183.1 - 1.4e-26 92.3 0.0 3.3e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Gemini_mov PF01708.16 RUS90183.1 - 0.3 10.9 2.7 1.1 9.1 2.7 2.1 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF4931 PF16285.5 RUS90183.1 - 4 6.7 7.2 0.26 10.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4931) MCD PF05292.11 RUS90184.1 - 3.1e-28 99.1 0.0 3.7e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain DUF4815 PF16075.5 RUS90184.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) MCD PF05292.11 RUS90185.1 - 1.5e-33 116.5 0.0 2.3e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 RUS90185.1 - 3.4e-12 46.3 0.1 5.2e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain DSPc PF00782.20 RUS90186.1 - 2.3e-20 72.7 0.1 2.9e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS90186.1 - 3.6e-05 23.4 0.4 4.5e-05 23.1 0.4 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RUS90186.1 - 6.9e-05 23.0 0.1 0.00012 22.3 0.1 1.5 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 RUS90186.1 - 0.0077 15.8 0.1 0.013 15.1 0.1 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 RUS90186.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 RUS90186.1 - 0.046 13.7 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 RUS90186.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPn PF14671.6 RUS90186.1 - 0.15 12.5 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half C2 PF00168.30 RUS90187.1 - 4.4e-12 46.2 0.1 1.4e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 C2 domain SMP_C2CD2L PF18696.1 RUS90187.1 - 3.3e-09 36.8 0.0 3.3e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Synaptotagmin-like, mitochondrial and lipid-binding domain SID-1_RNA_chan PF13965.6 RUS90187.1 - 0.2 10.0 0.1 0.32 9.3 0.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 RUS90187.1 - 3.9 5.6 23.8 7.7 4.6 23.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 RUS90187.1 - 4.8 6.7 29.0 13 5.3 29.0 1.8 1 0 0 1 1 1 0 Spt20 family DUF3540 PF12059.8 RUS90188.1 - 2.5e-06 27.5 1.7 0.0015 18.4 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3540) MIP PF00230.20 RUS90189.1 - 7.1e-18 65.1 1.2 8.2e-18 64.9 1.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Acyl_transf_3 PF01757.22 RUS90189.1 - 0.0019 17.3 0.2 0.0023 17.1 0.2 1.1 1 0 0 1 1 1 1 Acyltransferase family PDR_assoc PF08370.11 RUS90189.1 - 0.16 11.7 1.7 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated PsbJ PF01788.17 RUS90189.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.5 3 0 0 3 3 3 0 PsbJ DUF4131 PF13567.6 RUS90189.1 - 1.1 8.9 3.2 1.3 8.6 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF997 PF06196.12 RUS90189.1 - 1.4 9.0 6.1 0.38 10.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) XPA_C PF05181.12 RUS90190.1 - 0.00022 21.1 0.1 1e+02 3.0 0.0 5.5 1 1 8 10 10 10 0 XPA protein C-terminus FAM165 PF14981.6 RUS90190.1 - 0.81 9.5 38.0 48 3.9 0.1 10.5 1 1 11 12 12 12 0 FAM165 family Fibrinogen_C PF00147.18 RUS90191.1 - 2.8e-19 69.8 0.6 4e-19 69.3 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Redoxin PF08534.10 RUS90191.1 - 0.14 11.8 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Redoxin I-set PF07679.16 RUS90192.1 - 1.5e-27 95.5 0.0 1.7e-08 34.4 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90192.1 - 2.7e-26 92.0 4.4 5.4e-09 36.5 0.0 4.6 5 0 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 RUS90192.1 - 1.7e-21 76.3 0.5 3.3e-07 30.6 0.1 4.7 4 1 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 RUS90192.1 - 5.8e-16 58.4 0.4 3.9e-05 23.7 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS90192.1 - 2.1e-05 24.6 1.9 0.046 13.9 0.0 4.0 4 1 0 4 4 4 2 Immunoglobulin V-set domain fn3 PF00041.21 RUS90192.1 - 0.00018 21.8 0.1 0.00062 20.1 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Ig_6 PF18452.1 RUS90192.1 - 0.015 14.9 0.0 0.94 9.1 0.0 3.4 4 0 0 4 4 4 0 Immunoglobulin domain Izumo-Ig PF16706.5 RUS90192.1 - 0.016 15.2 0.0 4.5 7.4 0.0 3.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS90192.1 - 0.08 13.5 0.6 0.24 12.0 0.1 2.0 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF2457 PF10446.9 RUS90192.1 - 5.8 6.0 11.5 8.6 5.4 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Calponin PF00402.18 RUS90193.1 - 6.7e-121 393.3 84.8 1.2e-11 44.0 0.5 12.4 12 0 0 12 12 12 12 Calponin family repeat DUF4575 PF15143.6 RUS90193.1 - 0.03 14.5 1.8 2.4 8.4 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4575) adh_short PF00106.25 RUS90194.1 - 4.2e-38 130.8 0.1 5.7e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS90194.1 - 1e-22 80.8 0.0 1.8e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 RUS90194.1 - 9.7e-06 25.2 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 RUS90194.1 - 0.0003 20.8 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_35 PF01301.19 RUS90194.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 FtsK_alpha PF17854.1 RUS90194.1 - 0.05 13.8 0.1 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 FtsK alpha domain G_glu_transpept PF01019.21 RUS90195.1 - 5.1e-143 477.5 0.0 2e-142 475.6 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3040 PF11239.8 RUS90196.1 - 0.027 14.8 0.3 0.043 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Calponin PF00402.18 RUS90197.1 - 6.3e-239 770.7 142.8 1.5e-14 53.3 0.7 20.5 20 0 0 20 20 20 20 Calponin family repeat CH PF00307.31 RUS90197.1 - 4.1e-18 65.5 0.0 6.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Gal_GalNac_35kD PF17337.2 RUS90197.1 - 0.00056 20.0 0.0 2.6e+02 1.5 0.0 8.0 11 1 1 12 12 12 0 Galactose-inhibitable lectin 35 kDa subunit PATR PF12951.7 RUS90197.1 - 0.23 11.6 38.5 21 5.3 0.1 10.0 10 0 0 10 10 10 0 Passenger-associated-transport-repeat ubiquitin PF00240.23 RUS90199.1 - 0.00043 20.0 0.2 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 RUS90199.1 - 0.00065 20.1 0.3 0.0012 19.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ncstrn_small PF18266.1 RUS90200.1 - 3.5e-50 170.3 3.0 7.2e-45 153.0 0.1 2.8 2 1 0 3 3 3 2 Nicastrin small lobe Nicastrin PF05450.15 RUS90200.1 - 3.2e-18 66.1 0.1 5.2e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Nicastrin HMG_box PF00505.19 RUS90200.1 - 0.61 10.5 3.3 5.6 7.5 0.1 2.8 1 1 1 3 3 3 0 HMG (high mobility group) box C2 PF00168.30 RUS90201.1 - 6e-25 87.5 0.3 2.2e-11 43.9 0.0 2.6 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.6 RUS90201.1 - 0.089 12.4 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 CEP76 C2 domain DUF1375 PF07119.12 RUS90202.1 - 0.036 14.4 3.7 39 4.7 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1375) DUF3153 PF11353.8 RUS90202.1 - 0.058 13.0 0.3 0.085 12.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) YppF PF14178.6 RUS90202.1 - 0.09 12.7 4.4 16 5.5 0.5 4.3 2 2 0 2 2 2 0 YppF-like protein CDV3 PF15359.6 RUS90203.1 - 4.3e-28 98.4 8.0 4.3e-28 98.4 8.0 1.9 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 Nop14 PF04147.12 RUS90203.1 - 2.5 6.2 19.9 2.8 6.0 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family CARMIL_C PF16000.5 RUS90203.1 - 3.5 7.2 13.1 0.21 11.2 3.6 2.0 2 0 0 2 2 2 0 CARMIL C-terminus SFTA2 PF15210.6 RUS90204.1 - 0.0028 17.5 13.2 46 4.1 0.1 5.9 1 1 5 6 6 6 0 Surfactant-associated protein 2 DUF4522 PF15022.6 RUS90204.1 - 0.29 11.4 1.7 30 4.9 0.2 2.3 1 1 3 4 4 4 0 Protein of unknown function (DUF4522) 7TM_GPCR_Srd PF10317.9 RUS90204.1 - 0.31 10.2 36.3 3.1 6.9 1.5 5.0 1 1 4 5 5 5 0 Serpentine type 7TM GPCR chemoreceptor Srd Chlam_PMP PF02415.17 RUS90204.1 - 0.48 11.0 14.0 2.2e+02 2.7 0.1 5.9 6 0 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Carbam_trans_C PF16861.5 RUS90204.1 - 1.8 8.1 5.0 68 3.0 0.1 3.0 1 1 4 5 5 5 0 Carbamoyltransferase C-terminus ORC2 PF04084.14 RUS90205.1 - 1e-77 261.3 0.4 1e-77 261.3 0.4 1.5 2 0 0 2 2 2 1 Origin recognition complex subunit 2 DUF572 PF04502.13 RUS90205.1 - 1.5 8.4 10.7 2.3 7.8 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) 2OG-FeII_Oxy_3 PF13640.6 RUS90206.1 - 1.5e-15 57.8 0.1 3.1e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P4Ha_N PF08336.11 RUS90206.1 - 0.00025 21.1 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.20 RUS90206.1 - 0.08 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fz PF01392.22 RUS90207.1 - 0.029 15.0 0.2 0.031 14.9 0.2 1.2 1 0 0 1 1 1 0 Fz domain SMP_2 PF10144.9 RUS90207.1 - 0.32 10.6 2.1 4.9 6.8 0.4 2.6 1 1 2 3 3 3 0 Bacterial virulence factor haemolysin Prefoldin_3 PF13758.6 RUS90209.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit Macro PF01661.21 RUS90210.1 - 4e-10 39.8 0.0 7.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain Lectin_C PF00059.21 RUS90211.1 - 0.0024 18.6 0.1 0.0044 17.7 0.1 1.5 1 0 0 1 1 1 1 Lectin C-type domain Voldacs PF03517.13 RUS90211.1 - 0.8 9.8 13.1 2.1 8.4 13.1 1.7 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling FAM176 PF14851.6 RUS90211.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.2 2 1 1 3 3 3 0 FAM176 family Podoplanin PF05808.11 RUS90211.1 - 2.7 8.1 5.9 15 5.7 6.0 2.0 2 0 0 2 2 2 0 Podoplanin ATP-synt_D PF01813.17 RUS90212.1 - 0.00012 22.0 1.8 0.2 11.5 0.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit D MCCD1 PF15707.5 RUS90212.1 - 0.022 15.2 1.5 0.4 11.2 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 FlxA PF14282.6 RUS90212.1 - 0.43 10.6 6.5 0.17 11.9 1.3 2.4 2 0 0 2 2 2 0 FlxA-like protein PKI PF02827.16 RUS90212.1 - 0.58 10.4 4.7 1.4 9.2 4.7 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF4349 PF14257.6 RUS90212.1 - 0.91 8.9 6.1 0.12 11.8 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) RICTOR_N PF14664.6 RUS90213.1 - 0.0065 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term YL1 PF05764.13 RUS90213.1 - 0.099 12.8 3.4 0.15 12.1 3.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 RUS90213.1 - 0.099 12.4 4.0 0.17 11.6 4.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dishevelled PF02377.15 RUS90214.1 - 2.2e-46 158.3 19.1 2.2e-46 158.3 19.1 3.5 4 0 0 4 4 4 1 Dishevelled specific domain DIX PF00778.17 RUS90214.1 - 1.2e-30 105.1 0.0 2.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 RUS90214.1 - 1.4e-19 70.2 1.2 3e-19 69.2 1.2 1.6 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 RUS90214.1 - 3.7e-15 55.7 0.1 9.5e-15 54.4 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dsh_C PF12316.8 RUS90214.1 - 1.5e-10 41.8 14.3 1.5e-10 41.8 14.3 4.6 4 0 0 4 4 4 2 Segment polarity protein dishevelled (Dsh) C terminal PDZ_6 PF17820.1 RUS90214.1 - 2e-06 27.6 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS90214.1 - 0.0004 20.7 0.2 0.00096 19.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain LapA_dom PF06305.11 RUS90214.1 - 0.12 12.2 0.0 0.49 10.2 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 RUS90217.1 - 0.0093 16.9 2.2 0.021 15.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Tetraspanin PF00335.20 RUS90217.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family NicO PF03824.16 RUS90217.1 - 0.056 12.8 0.8 0.078 12.3 0.8 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein EphA2_TM PF14575.6 RUS90217.1 - 0.065 14.1 0.5 0.065 14.1 0.5 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2140 PF09911.9 RUS90217.1 - 0.088 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) SDA1 PF05285.12 RUS90218.1 - 0.017 14.5 7.1 0.018 14.5 7.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RUS90218.1 - 0.29 10.4 16.4 0.39 10.0 16.4 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RUS90218.1 - 2.5 6.3 4.6 2.8 6.1 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M13_N PF05649.13 RUS90219.1 - 8e-21 75.2 0.2 9.8e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Orf78 PF06024.12 RUS90219.1 - 0.00052 20.3 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) Piezo_RRas_bdg PF12166.8 RUS90219.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Baculo_11_kDa PF06143.11 RUS90219.1 - 0.0046 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family ECSCR PF15820.5 RUS90219.1 - 0.0069 16.2 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator ODV-E18 PF10717.9 RUS90219.1 - 0.0089 15.9 2.7 0.0089 15.9 2.7 1.5 1 1 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF5305 PF17231.2 RUS90219.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ETRAMP PF09716.10 RUS90219.1 - 0.031 14.3 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3328 PF11807.8 RUS90219.1 - 0.034 13.9 0.6 0.24 11.1 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3328) DUF4064 PF13273.6 RUS90219.1 - 0.035 14.4 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 RUS90219.1 - 0.046 14.6 0.0 0.067 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2721 PF11026.8 RUS90219.1 - 0.055 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) GRP PF07172.11 RUS90219.1 - 0.088 13.5 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family ARD PF03079.14 RUS90220.1 - 1.8e-30 106.2 0.3 2.2e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS90220.1 - 1.9e-09 37.1 0.1 3.2e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS90220.1 - 5.4e-06 26.3 0.0 5.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 RUS90220.1 - 0.0079 15.8 0.0 0.0093 15.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 RUS90220.1 - 0.048 13.4 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Cupin ARD PF03079.14 RUS90221.1 - 6.4e-48 162.9 0.9 7.3e-48 162.7 0.9 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 RUS90221.1 - 9.5e-09 34.9 0.1 2.2e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS90221.1 - 6.1e-05 22.9 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 RUS90221.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF2353 PF09789.9 RUS90223.1 - 2.7e-102 342.3 21.0 3.9e-102 341.8 21.0 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Tho2 PF11262.8 RUS90223.1 - 0.0061 15.8 2.0 0.0061 15.8 2.0 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 SlyX PF04102.12 RUS90223.1 - 0.036 14.7 16.7 2.4 8.9 0.0 4.6 3 1 1 4 4 4 0 SlyX DivIC PF04977.15 RUS90223.1 - 0.068 13.0 0.2 0.068 13.0 0.2 4.5 4 1 1 5 5 5 0 Septum formation initiator CENP-F_leu_zip PF10473.9 RUS90223.1 - 0.078 13.0 24.9 4.3 7.3 14.4 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 RUS90223.1 - 0.12 12.7 12.6 0.31 11.4 5.8 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Laminin_II PF06009.12 RUS90223.1 - 0.19 11.7 14.4 0.75 9.8 1.4 3.5 3 1 1 4 4 4 0 Laminin Domain II YabA PF06156.13 RUS90223.1 - 0.21 12.2 16.4 1.9 9.2 3.3 4.0 3 1 1 4 4 4 0 Initiation control protein YabA ADIP PF11559.8 RUS90223.1 - 0.22 11.6 20.4 3.6 7.7 0.3 4.2 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 RUS90223.1 - 0.54 10.9 21.3 13 6.4 4.1 5.3 4 1 0 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Myb_DNA-bind_5 PF13873.6 RUS90223.1 - 0.96 9.6 5.1 9 6.5 0.2 3.1 3 1 0 3 3 2 0 Myb/SANT-like DNA-binding domain ZapB PF06005.12 RUS90223.1 - 1.4 9.4 24.2 2.8 8.5 0.5 4.4 3 1 1 4 4 4 0 Cell division protein ZapB FlaC_arch PF05377.11 RUS90223.1 - 1.6 9.2 11.0 2.6 8.5 0.1 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 RUS90223.1 - 1.7 9.1 28.4 0.039 14.5 12.3 3.3 2 2 0 3 3 3 0 Apg6 coiled-coil region DUF4201 PF13870.6 RUS90223.1 - 1.9 8.2 24.5 0.33 10.7 6.3 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.11 RUS90223.1 - 2 8.2 13.2 1.2 8.9 2.0 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PRKG1_interact PF15898.5 RUS90223.1 - 2.9 8.9 23.6 0.95 10.4 8.4 3.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 RUS90223.1 - 3 5.6 6.9 3.9 5.3 6.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 RUS90223.1 - 4.3 7.4 11.1 0.096 12.8 0.8 3.3 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LMBR1 PF04791.16 RUS90223.1 - 5.1 5.9 10.4 6.3 5.6 4.3 2.0 1 1 0 2 2 2 0 LMBR1-like membrane protein DUF4140 PF13600.6 RUS90223.1 - 5.9 7.4 15.9 3.6 8.1 0.2 3.8 3 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.7 RUS90223.1 - 8.1 5.9 17.7 0.71 9.4 11.4 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 RUS90223.1 - 8.3 5.7 12.4 1 8.6 6.9 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_membrane PF00664.23 RUS90224.1 - 7.6e-102 340.6 10.6 1.8e-61 208.2 0.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS90224.1 - 9.1e-72 240.0 0.0 6.2e-35 120.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS90224.1 - 5.4e-12 45.6 0.0 8.2e-06 25.4 0.0 3.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS90224.1 - 2.3e-09 37.6 0.1 0.0022 18.3 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS90224.1 - 2.3e-08 34.6 0.2 0.0031 17.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RUS90224.1 - 3.9e-07 29.2 0.1 0.0029 16.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_7 PF12775.7 RUS90224.1 - 1.7e-06 27.7 0.0 0.0062 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 RUS90224.1 - 1.9e-06 27.9 0.0 0.024 14.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 RUS90224.1 - 8.3e-06 25.7 0.0 0.078 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 RUS90224.1 - 1.4e-05 25.1 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 RUS90224.1 - 1.6e-05 25.2 0.8 4.9 7.4 0.1 4.2 2 2 2 4 4 4 0 AAA domain AAA_5 PF07728.14 RUS90224.1 - 1.8e-05 24.7 0.1 0.49 10.4 0.0 3.5 5 0 0 5 5 2 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RUS90224.1 - 3.3e-05 23.5 0.3 0.36 10.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 RUS90224.1 - 0.00017 22.1 0.9 0.55 10.7 0.1 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 RUS90224.1 - 0.00017 21.8 2.4 0.35 11.1 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 RUS90224.1 - 0.00025 20.8 0.0 0.89 9.2 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 RUS90224.1 - 0.00025 20.4 0.0 0.21 10.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 RUS90224.1 - 0.00029 20.1 0.0 0.36 9.9 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 RUS90224.1 - 0.00046 19.8 0.0 0.17 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RUS90224.1 - 0.00046 20.5 0.0 2.4 8.6 0.0 3.2 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 RUS90224.1 - 0.0014 19.2 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 RUS90224.1 - 0.0015 18.6 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 1 tRNA ligase kinase domain DUF87 PF01935.17 RUS90224.1 - 0.0021 18.2 0.1 2.1 8.4 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_30 PF13604.6 RUS90224.1 - 0.0023 17.7 0.1 5 6.8 0.0 3.4 2 2 0 2 2 2 0 AAA domain PRK PF00485.18 RUS90224.1 - 0.0024 17.6 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 RUS90224.1 - 0.0044 16.9 0.0 0.81 9.4 0.0 3.3 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 RUS90224.1 - 0.0069 16.1 0.0 2.3 7.9 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 RUS90224.1 - 0.013 15.3 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 RUS90224.1 - 0.016 14.4 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 RUS90224.1 - 0.025 14.7 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 RUS90224.1 - 0.031 14.2 0.1 8.6 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 RUS90224.1 - 0.035 14.3 0.3 2.2 8.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 RUS90224.1 - 0.12 12.2 0.6 20 4.9 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 RUS90224.1 - 0.12 12.4 0.0 12 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 RUS90224.1 - 0.13 11.6 2.5 25 4.1 0.0 3.3 3 0 0 3 3 3 0 KaiC APS_kinase PF01583.20 RUS90224.1 - 0.15 12.0 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 RUS90224.1 - 0.17 11.1 0.0 7.7 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 RUS90224.1 - 0.17 11.6 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 RUS90225.1 - 1.9e-74 248.7 0.1 1e-36 126.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RUS90225.1 - 6.5e-73 245.7 5.2 2.4e-50 171.7 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 RUS90225.1 - 6.9e-14 51.8 4.4 1.3e-05 24.8 0.3 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS90225.1 - 1.8e-10 41.2 0.3 0.00064 20.0 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS90225.1 - 5.8e-09 36.6 1.2 0.0026 18.2 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RUS90225.1 - 5.8e-08 32.0 0.5 0.0012 17.8 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 RUS90225.1 - 1.5e-07 31.3 0.0 0.0062 16.2 0.0 2.5 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 RUS90225.1 - 1.9e-07 31.5 1.0 0.53 10.7 0.1 4.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RUS90225.1 - 1.1e-06 28.6 0.0 0.026 14.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 RUS90225.1 - 2.3e-06 27.6 0.0 0.052 13.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 RUS90225.1 - 2.4e-06 27.6 0.0 0.11 12.4 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_30 PF13604.6 RUS90225.1 - 2.5e-06 27.3 1.9 0.017 14.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 RUS90225.1 - 6e-06 25.9 0.0 0.018 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 RUS90225.1 - 6.7e-06 25.8 0.1 0.096 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RUS90225.1 - 2.2e-05 23.8 0.1 0.28 10.4 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.14 RUS90225.1 - 3.2e-05 24.0 0.3 0.67 10.0 0.0 4.2 5 0 0 5 5 4 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 RUS90225.1 - 4.4e-05 23.6 3.1 0.92 9.8 0.1 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 RUS90225.1 - 0.00014 21.2 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.22 RUS90225.1 - 0.00024 21.5 0.0 0.95 9.9 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_21 PF13304.6 RUS90225.1 - 0.00033 20.6 0.0 2.8 7.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 RUS90225.1 - 0.00046 19.4 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 RUS90225.1 - 0.0012 19.1 0.1 1.7 8.9 0.0 3.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS90225.1 - 0.0014 18.6 0.2 3 7.7 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.6 RUS90225.1 - 0.0018 18.3 0.5 13 5.9 0.0 4.3 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 RUS90225.1 - 0.0022 17.8 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RUS90225.1 - 0.0028 18.2 0.2 5.5 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 RUS90225.1 - 0.0029 17.7 0.1 2.2 8.3 0.0 2.9 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_25 PF13481.6 RUS90225.1 - 0.0033 17.0 0.0 0.88 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RUS90225.1 - 0.0034 17.1 0.0 0.19 11.5 0.0 3.1 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase PRK PF00485.18 RUS90225.1 - 0.0054 16.5 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 RUS90225.1 - 0.0085 16.0 0.0 18 5.2 0.0 3.5 3 0 0 3 3 3 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 RUS90225.1 - 0.012 15.7 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 RUS90225.1 - 0.013 14.7 0.1 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 RUS90225.1 - 0.034 14.3 0.0 3.4 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 RUS90225.1 - 0.057 13.0 0.0 4.2 6.9 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2594 PF10769.9 RUS90225.1 - 0.066 13.3 0.5 2.5 8.2 0.1 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF2594) AIG1 PF04548.16 RUS90225.1 - 0.12 11.7 0.0 9.2 5.5 0.0 2.5 2 0 0 2 2 2 0 AIG1 family AAA_18 PF13238.6 RUS90225.1 - 0.12 12.9 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RUS90225.1 - 0.14 11.9 1.8 20 4.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein RepB-RCR_reg PF10723.9 RUS90225.1 - 0.14 12.1 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 Replication regulatory protein RepB ABC_membrane PF00664.23 RUS90227.1 - 3.3e-28 99.1 6.5 9.7e-28 97.6 6.5 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region Integrin_beta PF00362.18 RUS90228.1 - 1.5e-108 362.2 0.0 2.1e-108 361.7 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 RUS90228.1 - 7.8e-25 86.3 1.2 1.5e-24 85.4 1.2 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain I-EGF_1 PF18372.1 RUS90228.1 - 3.9e-08 33.2 11.6 3.9e-08 33.2 11.6 7.1 8 1 0 8 8 8 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 RUS90228.1 - 2.5e-06 27.7 40.8 1.4e-05 25.4 16.6 7.4 6 2 2 8 8 8 4 EGF-like domain Neugrin PF06413.11 RUS90229.1 - 3.8e-12 46.7 6.7 7.3e-12 45.8 3.0 2.9 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 RUS90229.1 - 0.00029 21.0 1.1 0.00029 21.0 1.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 C_tripleX PF02363.19 RUS90232.1 - 0.014 15.6 35.3 1.8e+04 -19.0 35.3 4.9 1 1 0 1 1 1 0 Cysteine rich repeat HLH PF00010.26 RUS90233.1 - 4.1e-12 45.9 0.5 4.1e-12 45.9 0.5 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain KASH_CCD PF14662.6 RUS90233.1 - 0.0089 15.9 2.0 0.0089 15.9 2.0 1.5 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH CENP-Q PF13094.6 RUS90233.1 - 0.46 10.7 9.7 0.043 14.0 2.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med9 PF07544.13 RUS90233.1 - 1.2 9.3 7.6 0.3 11.2 3.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SWIB PF02201.18 RUS90234.1 - 4.5e-26 90.5 0.0 1e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 RUS90234.1 - 1.5e-14 53.7 2.1 1.5e-14 53.7 2.1 2.0 3 0 0 3 3 3 1 DEK C terminal domain eIF-3c_N PF05470.12 RUS90234.1 - 0.0039 15.6 9.8 0.004 15.5 9.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CSN5_C PF18323.1 RUS90234.1 - 0.15 12.9 0.4 0.15 12.9 0.4 3.2 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF4551 PF15087.6 RUS90234.1 - 0.16 10.8 9.2 0.18 10.6 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RRN3 PF05327.11 RUS90234.1 - 0.6 8.6 7.8 0.67 8.4 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LAP1C PF05609.12 RUS90234.1 - 1.2 8.1 11.8 1.6 7.8 11.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 RUS90234.1 - 1.8 6.8 18.2 2.5 6.3 18.2 1.3 1 0 0 1 1 1 0 CDC45-like protein HSCB_C PF07743.13 RUS90235.1 - 1.1e-17 64.2 0.5 7.6e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 RUS90235.1 - 1.1e-05 25.4 0.5 3.3e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Speriolin_C PF15059.6 RUS90235.1 - 0.0088 16.2 0.6 0.025 14.7 0.2 1.9 2 1 0 2 2 2 1 Speriolin C-terminus HscB_4_cys PF18256.1 RUS90235.1 - 0.082 12.7 2.8 0.17 11.7 2.8 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif SEA PF01390.20 RUS90235.1 - 0.097 12.8 0.7 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 SEA domain OrfB_Zn_ribbon PF07282.11 RUS90235.1 - 0.35 10.8 4.0 0.8 9.7 4.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pkinase_Tyr PF07714.17 RUS90236.1 - 8.2e-94 313.7 0.0 1.4e-93 312.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 RUS90236.1 - 1.3e-43 147.7 4.4 9.4e-24 83.7 0.0 3.2 3 0 0 3 3 3 2 Receptor L domain Pkinase PF00069.25 RUS90236.1 - 3.3e-41 141.4 0.0 5.3e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 RUS90236.1 - 4.2e-28 98.1 42.2 4.2e-28 98.1 42.2 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 RUS90236.1 - 1.7e-17 63.6 4.7 5.1e-06 26.7 0.0 5.0 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS90236.1 - 0.02 15.5 4.7 0.35 11.5 0.4 3.8 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Kinase-like PF14531.6 RUS90236.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FAM219A PF15260.6 RUS90238.1 - 1.1e-19 71.1 7.9 1.5e-19 70.6 7.0 1.7 1 1 1 2 2 2 1 Protein family FAM219A PTPLA PF04387.14 RUS90239.1 - 2.7e-47 160.5 9.7 2.7e-47 160.5 9.7 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 RUS90239.1 - 2.9e-05 25.0 0.0 5.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 RUS90240.1 - 2.9e-16 59.0 0.0 4.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS90240.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif XPG_I_2 PF12813.7 RUS90241.1 - 4.1e-18 65.8 0.0 1.5e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.17 RUS90241.1 - 2.2e-08 34.5 0.1 8.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 RUS90241.1 - 0.0003 21.1 0.1 0.0018 18.6 0.0 2.5 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc_N PF02739.16 RUS90241.1 - 0.058 13.3 0.0 0.26 11.2 0.0 2.0 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Attractin PF08037.11 RUS90241.1 - 0.18 11.8 3.3 13 5.9 0.4 3.2 2 0 0 2 2 2 0 Attractin family DUF1731 PF08338.11 RUS90242.1 - 1.1e-16 60.4 0.0 1.7e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 RUS90242.1 - 1.8e-10 40.7 0.0 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RUS90242.1 - 0.0013 18.2 0.0 0.0084 15.5 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 RUS90242.1 - 0.022 13.8 0.1 0.18 10.9 0.1 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 RUS90242.1 - 0.14 12.1 0.6 5.7 6.8 0.0 2.1 1 1 1 2 2 2 0 KR domain Trypsin PF00089.26 RUS90243.1 - 0.0043 16.9 0.1 0.0063 16.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 RUS90244.1 - 1.3e-08 35.0 0.3 1.6e-08 34.7 0.3 1.1 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 RUS90245.1 - 2.3e-39 135.5 0.1 3.5e-39 134.9 0.1 1.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS90245.1 - 2.6e-06 28.4 0.0 3.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RUS90246.1 - 9.9e-50 169.4 2.1 1.4e-49 168.9 2.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS90246.1 - 0.00022 22.2 0.2 0.00036 21.5 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 RUS90246.1 - 0.052 13.1 0.2 0.19 11.3 0.0 1.8 2 1 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Atx10homo_assoc PF09759.9 RUS90247.1 - 3.8e-07 30.0 0.3 6.6e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Fes1 PF08609.10 RUS90247.1 - 1.4e-06 29.1 1.4 4.9e-06 27.3 1.4 2.0 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 RUS90247.1 - 8.2e-05 22.5 1.1 0.07 13.4 0.2 4.0 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 RUS90247.1 - 0.00055 19.9 2.8 0.11 12.6 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RUS90247.1 - 0.0025 18.2 0.2 0.04 14.3 0.0 2.9 2 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RUS90247.1 - 0.0099 15.9 0.6 0.074 13.1 0.1 2.4 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RUS90247.1 - 0.035 14.6 0.1 0.18 12.4 0.1 2.4 1 0 0 1 1 1 0 HEAT-like repeat DUF3361 PF11841.8 RUS90247.1 - 0.071 13.0 3.4 0.38 10.7 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) KIP1 PF07765.12 RUS90247.1 - 2.5 8.3 5.4 2.6 8.2 1.1 2.9 3 0 0 3 3 3 0 KIP1-like protein Prefoldin PF02996.17 RUS90248.1 - 1.5e-19 70.0 0.2 3.7e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 RUS90248.1 - 2.5e-06 27.4 0.2 2.5e-06 27.4 0.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3460 PF11943.8 RUS90248.1 - 0.0046 17.2 1.6 0.019 15.2 1.6 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3460) Arfaptin PF06456.13 RUS90248.1 - 0.0083 15.7 0.1 0.0083 15.7 0.1 2.9 2 1 0 2 2 2 1 Arfaptin-like domain Prefoldin_2 PF01920.20 RUS90248.1 - 0.092 12.7 12.9 0.27 11.2 1.5 3.3 2 1 0 2 2 2 0 Prefoldin subunit DUF3835 PF12927.7 RUS90248.1 - 0.31 11.9 0.0 0.31 11.9 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3835) BUD22 PF09073.10 RUS90248.1 - 1.4 8.2 31.2 2.8 7.2 31.2 1.5 1 1 0 1 1 1 0 BUD22 FTA4 PF13093.6 RUS90248.1 - 1.5 8.7 13.5 32 4.3 13.5 2.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fzo_mitofusin PF04799.13 RUS90248.1 - 1.8 8.1 5.2 0.58 9.7 0.7 2.2 2 0 0 2 2 2 0 fzo-like conserved region EF-hand_1 PF00036.32 RUS90250.1 - 7.6e-17 59.5 2.7 7.1e-06 25.2 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 RUS90250.1 - 1.2e-13 51.3 5.2 5.7e-09 36.3 0.9 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS90250.1 - 3.4e-13 48.4 2.1 2.1e-05 24.1 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS90250.1 - 7.4e-12 44.9 2.5 8.5e-06 25.5 0.1 3.2 1 1 2 3 3 3 3 EF-hand domain pair Acyltransferase PF01553.21 RUS90250.1 - 1.7e-10 40.6 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.6 RUS90250.1 - 0.00011 21.5 0.5 0.0079 15.6 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 RUS90250.1 - 0.00064 19.6 0.1 0.0053 16.7 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RUS90250.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.25 RUS90251.1 - 7.6e-28 97.6 0.0 9.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90251.1 - 7.2e-16 58.2 0.0 8.4e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS90251.1 - 6.9e-11 41.5 0.0 8e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RUS90251.1 - 0.042 12.8 0.1 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RUS90251.1 - 0.088 12.2 0.5 0.13 11.6 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS90251.1 - 0.2 11.6 0.2 0.5 10.3 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family AlgF PF11182.8 RUS90252.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF AIG1 PF04548.16 RUS90253.1 - 2.2e-39 135.0 0.0 2.2e-39 135.0 0.0 2.2 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 RUS90253.1 - 1.1e-06 28.7 2.7 1.2e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 RUS90253.1 - 0.016 14.9 0.2 0.38 10.5 0.2 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.18 RUS90253.1 - 0.034 13.7 1.0 0.075 12.6 0.3 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Glycoprot_B_PH2 PF17417.2 RUS90253.1 - 0.045 14.1 0.3 0.13 12.7 0.1 1.8 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain ABC_tran PF00005.27 RUS90253.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.1 2 1 0 3 3 3 0 ABC transporter APG6_N PF17675.1 RUS90253.1 - 0.62 10.6 23.0 2.6 8.6 16.8 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 RUS90253.1 - 3.1 8.0 17.8 9.1 6.5 7.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Mito_carr PF00153.27 RUS90254.1 - 7.7e-53 176.4 2.9 1.7e-17 63.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 RUS90256.1 - 1.5e-39 135.6 0.0 2.7e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS90256.1 - 2.3e-25 89.1 0.1 7e-24 84.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS90256.1 - 1.6e-10 41.3 0.5 8.4e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RUS90256.1 - 0.00034 21.0 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS90256.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RUS90256.1 - 0.039 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 RUS90256.1 - 0.05 13.5 0.3 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Helicase T4SS-DNA_transf PF02534.14 RUS90256.1 - 0.061 12.1 0.4 0.42 9.3 0.0 2.0 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer PTA_PTB PF01515.19 RUS90256.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase PQQ_3 PF13570.6 RUS90256.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain AAA_11 PF13086.6 RUS90256.1 - 1.4 8.6 7.9 9.2 6.0 0.0 2.6 2 1 0 3 3 3 0 AAA domain TPR_1 PF00515.28 RUS90257.1 - 4.3e-73 238.4 39.1 2.8e-08 33.2 1.1 15.1 14 2 0 14 14 14 12 Tetratricopeptide repeat TPR_2 PF07719.17 RUS90257.1 - 2.8e-58 189.4 43.0 3.2e-07 30.0 1.0 14.3 13 2 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 RUS90257.1 - 4.3e-55 183.1 37.5 6.3e-09 35.4 0.2 13.8 7 4 7 14 14 14 12 TPR repeat TPR_8 PF13181.6 RUS90257.1 - 1.2e-46 153.0 18.3 8.1e-07 28.8 0.7 12.6 12 1 0 12 12 12 8 Tetratricopeptide repeat TPR_17 PF13431.6 RUS90257.1 - 3.9e-36 120.8 32.0 0.00036 20.7 0.4 12.9 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_9 PF13371.6 RUS90257.1 - 2e-29 101.5 23.5 0.0004 20.5 0.6 9.5 4 4 5 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 RUS90257.1 - 1.1e-26 93.2 36.2 7.6e-07 29.7 1.0 9.8 7 4 4 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 RUS90257.1 - 4.4e-26 91.0 34.8 1.3e-06 28.6 1.0 10.8 4 3 5 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 RUS90257.1 - 6.3e-21 74.7 26.0 5.2e-05 23.7 1.7 8.2 6 1 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 RUS90257.1 - 7.1e-20 70.0 22.7 0.00064 20.3 0.4 10.3 5 4 5 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 RUS90257.1 - 6.3e-16 57.2 17.6 0.0021 18.0 0.2 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 RUS90257.1 - 4.9e-14 52.0 25.9 0.039 14.6 0.6 11.3 12 0 0 12 12 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS90257.1 - 1.1e-09 38.4 28.4 9.8e-05 22.5 0.1 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RUS90257.1 - 1e-08 34.8 9.3 0.009 15.3 0.6 6.0 4 2 1 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 RUS90257.1 - 4.1e-06 26.1 19.8 0.21 11.1 0.0 8.1 9 0 0 9 9 8 2 SHNi-TPR NARP1 PF12569.8 RUS90257.1 - 8.4e-05 21.7 4.5 1.1 8.1 0.1 4.8 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 RUS90257.1 - 0.00022 21.0 8.6 0.072 12.8 1.4 4.6 2 1 3 5 5 5 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 RUS90257.1 - 0.0014 18.9 5.3 22 5.4 0.0 6.4 5 2 3 8 8 8 0 Tetratricopeptide repeat HemY_N PF07219.13 RUS90257.1 - 0.0055 16.9 0.6 14 6.0 0.0 4.8 5 0 0 5 5 5 0 HemY protein N-terminus TPR_10 PF13374.6 RUS90257.1 - 0.038 13.9 33.3 3.1 7.8 0.2 9.3 12 0 0 12 12 12 0 Tetratricopeptide repeat MIT PF04212.18 RUS90257.1 - 0.041 13.9 13.0 31 4.7 0.0 6.2 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain COPI_C PF06957.11 RUS90257.1 - 0.14 10.8 0.7 1.2 7.8 0.7 2.2 1 1 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TPR_5 PF12688.7 RUS90257.1 - 0.37 11.0 4.6 1.1e+02 3.1 0.1 5.1 5 1 0 6 6 6 0 Tetratrico peptide repeat BTAD PF03704.17 RUS90257.1 - 0.84 10.1 7.5 18 5.7 0.2 3.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain DUF627 PF04781.12 RUS90257.1 - 2.3 8.2 7.3 19 5.3 0.2 4.6 5 0 0 5 5 4 0 Protein of unknown function (DUF627) DNA_ligase_A_N PF04675.14 RUS90258.1 - 0.36 11.2 2.9 0.57 10.5 1.3 2.1 2 0 0 2 2 2 0 DNA ligase N terminus Anoctamin PF04547.12 RUS90258.1 - 0.53 9.1 4.7 6.3 5.5 0.9 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel AAA_23 PF13476.6 RUS90258.1 - 1.4 9.4 7.5 2.8 8.4 7.5 1.5 1 0 0 1 1 1 0 AAA domain Orf78 PF06024.12 RUS90258.1 - 1.6 9.1 5.6 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) MAP7 PF05672.11 RUS90258.1 - 2.2 8.0 19.9 0.14 11.8 14.8 1.6 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF1651 PF07864.11 RUS90260.1 - 1.2e-05 25.6 0.1 0.6 10.5 0.0 4.5 1 1 3 4 4 4 1 Protein of unknown function (DUF1651) DDT PF02791.17 RUS90260.1 - 0.034 14.4 0.3 0.31 11.4 0.1 2.4 2 0 0 2 2 2 0 DDT domain DUF1093 PF06486.11 RUS90260.1 - 0.045 14.4 7.4 36 5.1 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1093) BTB PF00651.31 RUS90261.1 - 8.3e-13 48.5 1.6 6e-06 26.5 0.4 2.7 2 0 0 2 2 2 2 BTB/POZ domain zf-C2H2 PF00096.26 RUS90261.1 - 3.7e-12 46.0 50.0 0.0001 22.6 3.5 7.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS90261.1 - 1.6e-08 34.7 47.3 0.0018 19.0 2.7 7.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS90261.1 - 3.3e-07 30.4 0.5 3.3e-07 30.4 0.5 6.4 6 0 0 6 6 6 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 RUS90261.1 - 3.6e-06 26.6 1.5 3.6e-06 26.6 1.5 3.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS90261.1 - 1.7e-05 25.0 35.2 0.005 17.1 1.2 6.9 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS90261.1 - 0.003 17.9 39.2 0.0091 16.4 0.9 7.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type LRR_6 PF13516.6 RUS90264.1 - 8.8e-11 41.0 11.7 0.19 11.8 0.1 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 RUS90264.1 - 3.8 8.1 7.5 3.3 8.3 0.5 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Lectin_C PF00059.21 RUS90265.1 - 1.1e-16 61.5 0.3 1.4e-16 61.2 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain PseudoU_synth_1 PF01416.20 RUS90266.1 - 9e-12 45.4 0.0 2.2e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 tRNA pseudouridine synthase PseudoU_synth_1 PF01416.20 RUS90267.1 - 0.00015 22.2 0.1 0.0002 21.8 0.1 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF5441 PF17513.2 RUS90267.1 - 0.13 12.0 0.1 6.8 6.4 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5441) NDUF_B5 PF09781.9 RUS90268.1 - 1.4e-48 165.0 1.3 1.6e-48 164.8 1.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DnaJ PF00226.31 RUS90269.1 - 8.1e-18 64.3 0.4 8.1e-18 64.3 0.4 2.3 3 0 0 3 3 3 1 DnaJ domain DUF4200 PF13863.6 RUS90269.1 - 0.01 16.2 4.7 0.01 16.2 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2151 PF10221.9 RUS90269.1 - 0.035 12.7 0.8 0.046 12.3 0.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator OAD_gamma PF04277.13 RUS90269.1 - 0.082 13.5 2.7 0.17 12.5 2.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4407 PF14362.6 RUS90269.1 - 0.085 12.2 7.4 0.11 11.9 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_8 PF12780.7 RUS90269.1 - 0.14 11.4 0.2 0.25 10.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DUF1266 PF06889.11 RUS90269.1 - 0.76 9.8 6.7 0.092 12.8 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) AAA_23 PF13476.6 RUS90269.1 - 2.9 8.4 10.2 3.9 7.9 10.2 1.4 1 1 0 1 1 1 0 AAA domain BCA_ABC_TP_C PF12399.8 RUS90270.1 - 2 8.4 0.0 2 8.4 0.0 5.6 6 0 0 6 6 6 0 Branched-chain amino acid ATP-binding cassette transporter Mitofilin PF09731.9 RUS90270.1 - 3 6.6 11.2 3.4 6.4 11.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BAH PF01426.18 RUS90272.1 - 6.4e-15 55.1 0.9 5.9e-14 52.0 0.1 2.5 2 1 0 2 2 2 1 BAH domain ELM2 PF01448.24 RUS90272.1 - 2.8e-11 44.0 0.0 1.1e-10 42.1 0.0 2.1 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 RUS90272.1 - 1.6e-06 27.6 2.4 1.6e-06 27.6 2.4 2.0 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-binding PF00249.31 RUS90272.1 - 0.0044 17.2 0.6 0.0082 16.3 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Atrophin-1 PF03154.15 RUS90274.1 - 1.2e-06 27.2 5.1 1.3e-06 27.1 5.1 1.1 1 0 0 1 1 1 1 Atrophin-1 family DUF1115 PF06544.12 RUS90276.1 - 3e-13 50.1 0.1 2.1e-12 47.3 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1115) zf-H2C2_2 PF13465.6 RUS90277.1 - 4.3e-14 52.2 29.3 3.3e-09 36.7 0.9 5.2 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 RUS90277.1 - 2.1e-13 49.9 32.5 7.6e-05 23.0 3.4 4.4 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS90277.1 - 6e-11 42.2 28.1 0.00051 20.7 0.7 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS90277.1 - 6.9e-09 35.8 7.9 0.00048 20.3 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS90277.1 - 0.00075 19.8 5.5 0.021 15.2 0.2 4.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RUS90277.1 - 0.0019 18.4 0.3 0.0019 18.4 0.3 3.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 RUS90277.1 - 0.0025 18.2 2.4 0.18 12.3 0.1 3.2 2 1 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-MYST PF17772.1 RUS90277.1 - 0.0029 17.2 11.2 1.5 8.5 0.1 3.9 3 1 1 4 4 4 2 MYST family zinc finger domain zf-C2H2_6 PF13912.6 RUS90277.1 - 0.0054 16.7 0.2 0.0054 16.7 0.2 4.4 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 RUS90277.1 - 0.0093 16.6 12.5 0.096 13.4 0.9 2.5 2 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 RUS90277.1 - 0.057 13.3 2.4 0.6 10.0 0.1 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) FpoO PF10621.9 RUS90277.1 - 0.084 13.2 2.1 0.28 11.5 2.1 1.9 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF2225 PF09986.9 RUS90277.1 - 0.14 11.9 6.2 0.82 9.4 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 RUS90277.1 - 0.24 12.2 7.8 1.7 9.4 2.0 2.5 1 1 1 2 2 2 0 zinc-ribbon family zinc_ribbon_10 PF10058.9 RUS90277.1 - 0.31 10.8 7.6 1.3 8.9 0.6 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_2 PF12756.7 RUS90277.1 - 0.32 11.3 17.3 5.9 7.3 0.1 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 RUS90277.1 - 0.42 10.8 15.2 2.5 8.3 13.0 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf_UBZ PF18439.1 RUS90277.1 - 0.45 10.2 9.8 1.2 8.7 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 RUS90277.1 - 0.67 10.1 16.9 1.2 9.3 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-Mss51 PF13824.6 RUS90277.1 - 1 9.5 11.8 9.3 6.4 11.8 2.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 XPA_N PF01286.18 RUS90277.1 - 1.2 9.2 10.5 14 5.8 0.2 4.1 4 0 0 4 4 4 0 XPA protein N-terminal PhnA_Zn_Ribbon PF08274.12 RUS90277.1 - 1.4 9.0 0.1 1.4 9.0 0.1 3.3 4 0 0 4 4 3 0 PhnA Zinc-Ribbon FYVE_2 PF02318.16 RUS90277.1 - 2.7 8.2 11.1 66 3.7 10.1 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger ADK_lid PF05191.14 RUS90277.1 - 2.7 8.0 8.9 1.8 8.6 1.1 3.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid UBZ_FAAP20 PF15750.5 RUS90277.1 - 4.7 7.2 10.1 17 5.5 0.9 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-B_box PF00643.24 RUS90277.1 - 8 6.7 18.0 11 6.2 3.1 3.7 2 1 2 4 4 4 0 B-box zinc finger Baculo_11_kDa PF06143.11 RUS90281.1 - 0.83 9.3 4.3 1.1 8.9 4.3 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family MamL-1 PF09596.10 RUS90282.1 - 3.3e-18 65.7 2.8 3.3e-18 65.7 2.8 1.5 2 0 0 2 2 2 1 MamL-1 domain HSP90 PF00183.18 RUS90283.1 - 4.5e-97 326.1 7.0 4.1e-94 316.3 3.2 2.3 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 RUS90283.1 - 9.8e-11 41.6 0.1 2.1e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS90283.1 - 2.6e-06 27.9 0.1 5e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_C PF00137.21 RUS90284.1 - 1.6e-34 118.0 36.1 4.5e-22 78.1 14.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GEMIN8 PF15348.6 RUS90285.1 - 3.7e-41 141.9 0.5 3.7e-41 141.9 0.5 2.5 3 1 0 3 3 3 1 Gemini of Cajal bodies-associated protein 8 RWD PF05773.22 RUS90286.1 - 9.7e-20 71.0 0.1 4.7e-19 68.8 0.1 2.2 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 RUS90286.1 - 8.4e-18 64.4 38.4 3.5e-12 46.3 3.9 4.1 3 1 0 4 4 4 2 IBR domain, a half RING-finger domain FYVE PF01363.21 RUS90286.1 - 7.8 6.7 30.2 3.9 7.7 5.1 3.5 3 0 0 3 3 3 0 FYVE zinc finger DNA_pol_phi PF04931.13 RUS90287.1 - 0.0073 14.5 32.4 0.0093 14.1 32.4 1.0 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 RUS90287.1 - 0.028 12.8 10.8 0.038 12.3 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RUS90287.1 - 0.16 11.1 6.9 0.23 10.6 6.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 RUS90287.1 - 0.25 10.9 14.6 0.37 10.3 14.6 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 RUS90287.1 - 0.26 9.5 20.1 0.34 9.1 20.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RUS90287.1 - 0.56 9.6 19.1 0.76 9.1 19.1 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RUS90287.1 - 4.5 7.1 16.1 7.6 6.4 16.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region COPI_C PF06957.11 RUS90287.1 - 9.4 4.9 10.0 13 4.4 10.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ras PF00071.22 RUS90290.1 - 4e-55 185.8 0.0 4.9e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS90290.1 - 7.9e-32 110.0 0.0 1.8e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS90290.1 - 1.3e-11 44.3 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS90290.1 - 2.3e-06 27.3 0.0 2.7e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS90290.1 - 2.6e-06 27.5 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS90290.1 - 4.6e-05 22.9 0.2 7.8e-05 22.1 0.2 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RUS90290.1 - 5.6e-05 23.1 0.1 0.0033 17.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 RUS90290.1 - 0.0029 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 RUS90290.1 - 0.0054 16.3 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 RUS90290.1 - 0.0092 16.4 0.0 0.023 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 RUS90290.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family G-alpha PF00503.20 RUS90290.1 - 0.035 13.3 1.9 5.5 6.0 0.1 2.8 1 1 1 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 RUS90290.1 - 0.072 13.0 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RUS90290.1 - 0.11 13.1 0.5 0.18 12.3 0.5 1.7 1 1 0 1 1 1 0 ABC transporter Laminin_G_3 PF13385.6 RUS90291.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TMEM171 PF15471.6 RUS90291.1 - 0.082 11.9 1.7 0.1 11.6 1.7 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 La PF05383.17 RUS90292.1 - 2.9e-21 75.3 0.7 5.9e-21 74.3 0.7 1.6 1 0 0 1 1 1 1 La domain PTS_2-RNA PF01885.16 RUS90292.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Phage_XkdX PF09693.10 RUS90292.1 - 0.032 14.2 0.5 0.078 13.0 0.5 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) MH2 PF03166.14 RUS90293.1 - 3.5e-74 249.0 2.0 5e-74 248.6 2.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 RUS90293.1 - 2.7e-41 139.9 2.5 2.7e-41 139.9 2.5 2.2 3 0 0 3 3 3 1 MH1 domain IRF-3 PF10401.9 RUS90293.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 PGM_PMM_II PF02879.16 RUS90294.1 - 1.2e-20 74.0 0.1 3.5e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 RUS90294.1 - 8.5e-13 48.5 0.1 1.7e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 RUS90294.1 - 2.6e-07 30.7 0.0 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Peptidase_C1 PF00112.23 RUS90295.1 - 2.5e-56 191.2 1.3 3.5e-56 190.7 1.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 RUS90295.1 - 3.6e-10 40.1 0.2 6.9e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 RUS90295.1 - 3.9e-06 25.9 0.5 0.00087 18.2 0.0 3.3 3 1 0 4 4 4 1 Peptidase C1-like family Peptidase_C70 PF12385.8 RUS90295.1 - 0.046 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 BtrH_N PF14399.6 RUS90295.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Peripla_BP_6 PF13458.6 RUS90296.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DNA_pol_phi PF04931.13 RUS90296.1 - 0.44 8.6 44.9 0.67 8.0 44.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS90296.1 - 10 4.2 37.2 0.12 10.5 27.4 1.9 2 0 0 2 2 2 0 Nop14-like family Apolipoprotein PF01442.18 RUS90297.1 - 1e-10 41.8 27.2 0.00019 21.4 9.2 4.4 2 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain V-ATPase_G PF03179.15 RUS90297.1 - 0.15 12.6 20.4 0.076 13.5 3.3 3.3 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Prominin PF05478.11 RUS90297.1 - 0.26 9.2 2.5 0.41 8.5 2.5 1.4 1 0 0 1 1 1 0 Prominin DUF4455 PF14643.6 RUS90297.1 - 0.45 9.1 5.0 1 7.9 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF842 PF05811.13 RUS90297.1 - 2.7 7.7 10.4 13 5.5 7.7 3.4 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Syntaxin-6_N PF09177.11 RUS90297.1 - 4.9 7.8 6.6 11 6.6 3.1 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal GIT1_C PF12205.8 RUS90297.1 - 8.8 6.5 11.6 4 7.6 4.9 2.7 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Pkinase PF00069.25 RUS90298.1 - 2.9e-65 220.3 0.0 7.4e-65 218.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90298.1 - 6.3e-29 101.0 0.2 1.3e-27 96.8 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase DCX PF03607.17 RUS90298.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Doublecortin PX PF00787.24 RUS90299.1 - 9e-23 80.4 0.2 3e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 PX domain FAM92 PF06730.11 RUS90299.1 - 0.00018 21.0 0.7 0.00018 21.0 0.7 2.2 2 0 0 2 2 2 1 FAM92 protein Vps5 PF09325.10 RUS90299.1 - 0.0021 17.7 10.4 0.0067 16.0 2.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF4817 PF16087.5 RUS90299.1 - 0.12 12.2 0.5 0.28 11.0 0.5 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) CREPT PF16566.5 RUS90299.1 - 3.2 7.9 8.2 3.3 7.9 0.4 2.8 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Borealin PF10512.9 RUS90300.1 - 4.9e-11 42.7 0.1 1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 RUS90300.1 - 0.21 11.3 1.0 0.39 10.4 0.2 1.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal tRNA-synt_2 PF00152.20 RUS90301.1 - 2.4e-76 256.8 0.1 5.3e-76 255.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RUS90301.1 - 2.2e-07 30.8 2.6 4.1e-07 29.9 2.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RUS90301.1 - 0.0005 19.6 0.1 0.26 10.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 RUS90301.1 - 0.0045 17.2 0.1 0.0093 16.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 RUS90301.1 - 0.67 8.8 5.5 0.99 8.2 5.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-C2H2 PF00096.26 RUS90302.1 - 4.3e-12 45.8 13.4 0.003 17.9 2.4 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS90302.1 - 2e-09 37.5 12.6 0.0034 18.1 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS90302.1 - 2.6e-08 33.5 11.6 0.00016 21.3 3.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 RUS90302.1 - 2.2e-06 27.8 7.2 0.077 13.3 0.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RUS90302.1 - 5.5e-05 23.4 19.2 0.0061 16.9 1.4 4.2 4 1 0 4 4 3 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 RUS90302.1 - 0.0031 17.8 8.6 0.033 14.5 3.2 2.9 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RUS90302.1 - 0.0056 16.6 0.1 0.0056 16.6 0.1 2.7 3 0 0 3 3 2 1 zinc-finger of a C2HC-type AKAP95 PF04988.12 RUS90302.1 - 0.015 15.5 0.4 0.015 15.5 0.4 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zinc_ribbon_9 PF14369.6 RUS90302.1 - 0.026 14.8 0.1 0.026 14.8 0.1 2.0 2 0 0 2 2 1 0 zinc-ribbon zf-Di19 PF05605.12 RUS90302.1 - 0.031 14.6 8.8 2.2 8.7 5.0 2.3 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 RUS90302.1 - 0.066 13.6 2.9 0.066 13.6 2.9 3.2 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 RUS90302.1 - 0.096 12.5 1.4 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 RUS90302.1 - 0.21 11.7 0.0 0.21 11.7 0.0 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger HypA PF01155.19 RUS90302.1 - 0.24 11.4 4.0 0.46 10.5 3.9 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 RUS90302.1 - 0.43 11.1 4.7 7.3 7.1 0.1 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RUS90302.1 - 0.53 10.0 7.2 11 5.7 0.6 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Endonuclease_7 PF02945.15 RUS90302.1 - 0.71 9.8 8.9 0.79 9.7 4.6 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII CpXC PF14353.6 RUS90302.1 - 2.3 8.3 9.0 24 5.0 3.9 3.0 1 1 1 2 2 2 0 CpXC protein Elf1 PF05129.13 RUS90302.1 - 5 7.2 7.6 0.65 10.1 2.3 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like TMEM171 PF15471.6 RUS90304.1 - 3.3 6.6 6.4 0.12 11.3 0.4 1.6 1 1 1 2 2 2 0 Transmembrane protein family 171 PNRC PF15365.6 RUS90307.1 - 0.058 13.2 0.4 0.058 13.2 0.4 1.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Homeodomain PF00046.29 RUS90308.1 - 2.9e-21 75.0 5.0 5.9e-21 74.1 5.0 1.5 1 0 0 1 1 1 1 Homeodomain TFIIA PF03153.13 RUS90308.1 - 0.078 13.0 41.8 0.15 12.0 41.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 RUS90308.1 - 0.51 9.9 16.6 0.032 13.8 4.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CBP4 PF07960.11 RUS90308.1 - 7.8 6.4 14.5 0.57 10.0 9.5 1.6 2 0 0 2 2 2 0 CBP4 THAP PF05485.12 RUS90309.1 - 3.9e-06 27.7 2.0 8.2e-06 26.7 2.0 1.6 1 0 0 1 1 1 1 THAP domain PMSR PF01625.21 RUS90310.1 - 1.5e-64 216.8 5.7 2e-64 216.4 5.7 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase BRAP2 PF07576.12 RUS90310.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 IspD PF01128.19 RUS90311.1 - 2.9e-38 131.8 0.0 4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 RUS90311.1 - 1.2e-08 35.5 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain TPALS PF18178.1 RUS90311.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 TIR- and PNP-associating SLOG family RPAP3_C PF13877.6 RUS90312.1 - 0.0004 20.9 0.1 0.0017 18.8 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Hypoth_Ymh PF09509.10 RUS90312.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Acyl_transf_3 PF01757.22 RUS90313.1 - 2.6e-10 39.9 4.0 3.5e-10 39.5 4.0 1.2 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.22 RUS90314.1 - 6.4e-05 22.2 10.9 7.6e-05 21.9 10.9 1.1 1 0 0 1 1 1 1 Acyltransferase family COPI_C PF06957.11 RUS90316.1 - 1.1e-186 620.5 0.0 1.4e-186 620.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 RUS90316.1 - 1.2e-141 472.8 0.7 1.2e-141 472.8 0.7 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RUS90316.1 - 3e-40 135.4 16.7 1.2e-07 32.2 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS90316.1 - 5.6e-08 33.0 1.1 0.00037 20.7 0.0 4.9 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 RUS90316.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 LisH Nup160 PF11715.8 RUS90316.1 - 0.32 9.6 3.4 2.3 6.8 0.1 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WAP PF00095.21 RUS90317.1 - 8.2e-05 22.9 10.6 8.2e-05 22.9 10.6 2.3 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' ORF11CD3 PF10549.9 RUS90318.1 - 0.22 11.6 16.5 15 5.8 0.2 5.2 1 1 4 7 7 7 0 ORF11CD3 domain PilN_bio_d PF18222.1 RUS90318.1 - 1.2 9.5 5.1 47 4.5 0.4 3.4 1 1 3 5 5 5 0 PilN biogenesis protein dimerization domain Sulfatase PF00884.23 RUS90319.1 - 3e-54 184.5 1.0 3.8e-54 184.2 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS90319.1 - 0.0017 18.0 1.2 0.0042 16.7 1.2 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 RUS90319.1 - 0.022 15.5 0.0 0.11 13.3 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 RUS90319.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function CDC45 PF02724.14 RUS90321.1 - 0.042 12.2 20.8 0.059 11.7 20.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RUS90321.1 - 0.08 11.0 44.4 0.099 10.7 44.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS90321.1 - 0.46 8.6 30.1 0.56 8.3 30.1 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 RUS90321.1 - 1.5 7.3 26.8 1.9 6.9 26.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 RUS90321.1 - 5.3 6.4 22.5 7.7 5.8 22.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1157 PF06636.11 RUS90322.1 - 6.1e-05 22.0 1.2 0.69 8.7 0.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF1157) Ndr PF03096.14 RUS90322.1 - 0.014 14.1 2.9 0.39 9.4 0.8 2.2 1 1 1 2 2 2 0 Ndr family DUF3447 PF11929.8 RUS90322.1 - 0.065 13.2 4.3 2.4 8.2 0.8 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) SATase_N PF06426.14 RUS90322.1 - 0.095 13.1 0.1 1.9 8.9 0.0 1.9 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal DUF2883 PF11097.8 RUS90322.1 - 0.35 11.0 1.6 86 3.3 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2883) PBS_linker_poly PF00427.21 RUS90322.1 - 0.41 10.7 6.5 26 4.9 0.3 3.1 1 1 2 3 3 3 0 Phycobilisome Linker polypeptide Vanabin-2 PF11437.8 RUS90322.1 - 0.59 10.3 11.1 0.42 10.8 9.6 1.5 1 1 0 1 1 1 0 Vanadium-binding protein 2 IFRD_C PF04836.12 RUS90322.1 - 0.67 10.6 5.2 25 5.6 1.1 3.2 1 1 2 3 3 3 0 Interferon-related protein conserved region Myb_DNA-bind_6 PF13921.6 RUS90322.1 - 1.1 9.5 8.8 50 4.3 0.1 4.5 2 1 1 4 4 4 0 Myb-like DNA-binding domain Homeodomain PF00046.29 RUS90323.1 - 1.1e-31 108.4 14.0 6.4e-20 70.8 9.4 2.4 2 0 0 2 2 2 2 Homeodomain Abdominal-A PF12407.8 RUS90323.1 - 5.3e-07 29.1 1.3 0.037 13.6 0.1 2.8 2 0 0 2 2 2 2 Homeobox protein ResB PF05140.14 RUS90323.1 - 0.0044 15.8 0.3 1.6 7.4 0.0 2.1 2 0 0 2 2 2 2 ResB-like family zf-PARP PF00645.18 RUS90323.1 - 0.012 16.5 1.8 5.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region YfmQ PF10787.9 RUS90323.1 - 0.033 14.0 0.2 8.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group Terminase_5 PF06056.12 RUS90323.1 - 0.034 14.0 1.1 6.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Homez PF11569.8 RUS90323.1 - 0.081 12.4 0.5 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez TUTF7_u4 PF16631.5 RUS90323.1 - 0.084 13.5 7.2 2.9 8.6 0.8 2.4 2 0 0 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 MAGI_u5 PF16666.5 RUS90323.1 - 0.088 13.0 4.1 6.3 7.0 0.1 2.5 2 1 0 2 2 2 0 Unstructured region on MAGI Prothymosin PF03247.14 RUS90323.1 - 0.21 12.0 10.0 0.95 9.9 3.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF3677 PF12432.8 RUS90323.1 - 0.34 11.3 2.9 16 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Pex14_N PF04695.13 RUS90323.1 - 0.8 10.4 5.6 3.6 8.2 1.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OSR1_C PF12202.8 RUS90323.1 - 1.1 9.5 3.6 25 5.2 0.3 2.3 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain Homeobox_KN PF05920.11 RUS90323.1 - 1.4 8.9 13.5 0.71 9.8 0.7 2.9 3 0 0 3 3 2 0 Homeobox KN domain DUF1180 PF06679.12 RUS90323.1 - 6 7.3 6.3 0.77 10.2 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Peptidase_M18 PF02127.15 RUS90324.1 - 7.1e-183 608.3 0.0 8.1e-183 608.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 RUS90324.1 - 8.9e-06 24.9 0.2 3.1e-05 23.1 0.3 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase LRR_9 PF14580.6 RUS90325.1 - 2e-09 37.2 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 RUS90325.1 - 6.2e-08 32.3 0.2 0.00068 19.4 0.0 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS90325.1 - 1.8e-07 31.3 0.3 0.002 18.5 0.0 3.9 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) GGACT PF06094.12 RUS90326.1 - 1e-12 48.8 0.1 5.4e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like MIP-T3 PF10243.9 RUS90328.1 - 5e-48 161.8 0.4 1.2e-47 160.6 0.4 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 RUS90328.1 - 7.5e-43 146.1 15.2 7.5e-43 146.1 15.2 3.0 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Fib_alpha PF08702.10 RUS90328.1 - 0.0014 18.8 6.6 0.0021 18.2 4.9 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family GLE1 PF07817.13 RUS90328.1 - 0.038 13.2 6.6 0.24 10.6 0.5 2.3 1 1 1 2 2 2 0 GLE1-like protein TolA_bind_tri PF16331.5 RUS90328.1 - 0.16 12.1 11.1 0.16 12.0 0.6 3.1 1 1 2 3 3 3 0 TolA binding protein trimerisation BCDHK_Adom3 PF10436.9 RUS90329.1 - 1.1e-40 139.1 0.8 1.7e-40 138.5 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RUS90329.1 - 2.2e-13 50.7 0.0 6.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RUS90329.1 - 0.00034 20.4 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase REC104 PF17378.2 RUS90329.1 - 0.078 12.8 0.1 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Meiotic recombination protein REC104 ArgoMid PF16487.5 RUS90329.1 - 0.11 12.8 0.1 14 6.1 0.0 3.0 2 1 1 3 3 3 0 Mid domain of argonaute NEMP PF10225.9 RUS90330.1 - 6.2e-34 117.8 10.2 8.6e-34 117.3 10.2 1.1 1 0 0 1 1 1 1 NEMP family COX14 PF14880.6 RUS90331.1 - 4.8e-09 35.9 5.6 1e-08 34.9 5.6 1.8 1 1 0 1 1 1 1 Cytochrome oxidase c assembly HEXIM PF15313.6 RUS90332.1 - 1.3e-20 74.0 2.2 1.3e-20 74.0 2.2 2.7 3 0 0 3 3 3 1 Hexamethylene bis-acetamide-inducible protein McrBC PF10117.9 RUS90332.1 - 0.034 13.3 0.1 0.054 12.6 0.1 1.3 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component MADF_DNA_bdg PF10545.9 RUS90333.1 - 2e-15 56.9 0.8 4.9e-15 55.6 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rox3 PF08633.10 RUS90333.1 - 0.0075 16.6 0.5 0.02 15.2 0.6 1.6 1 1 0 1 1 1 1 Rox3 mediator complex subunit DUF573 PF04504.14 RUS90333.1 - 0.042 14.5 0.3 0.13 13.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF573 C_tripleX PF02363.19 RUS90334.1 - 9.4 6.8 54.1 6.4 7.3 1.4 7.8 3 2 1 4 4 4 0 Cysteine rich repeat TGF_beta PF00019.20 RUS90336.1 - 2e-09 38.3 7.1 4.3e-09 37.3 7.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 RUS90336.1 - 4.9e-05 23.2 0.3 0.00012 22.0 0.1 1.7 2 0 0 2 2 2 1 TGF-beta propeptide DUF4523 PF15023.6 RUS90337.1 - 0.00064 19.6 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Methyltransf_15 PF09445.10 RUS90338.1 - 6.7e-44 149.4 0.1 1e-43 148.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 RUS90338.1 - 7.4e-09 35.6 0.5 2.6e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS90338.1 - 1.2e-08 35.6 0.0 8.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 RUS90338.1 - 9.4e-08 32.0 0.1 9.5e-07 28.7 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 RUS90338.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 RUS90338.1 - 3.3e-05 23.9 0.0 8.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS90338.1 - 0.00025 21.7 0.0 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 RUS90338.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 RUS90338.1 - 0.0025 17.4 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RUS90338.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 RUS90338.1 - 0.024 14.0 2.0 0.025 14.0 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 RUS90338.1 - 0.034 13.3 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TRM PF02005.16 RUS90338.1 - 0.091 11.9 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase LZ_Tnp_IS66 PF13007.7 RUS90338.1 - 2.8 8.8 10.7 2.8 8.8 1.4 3.6 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Ribosomal_L7Ae PF01248.26 RUS90339.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Tryp_alpha_amyl PF00234.22 RUS90340.1 - 0.013 15.9 0.5 0.023 15.1 0.5 1.5 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family SSF PF00474.17 RUS90341.1 - 1.3e-09 37.5 8.2 1.4e-09 37.3 8.2 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Fn3-like PF14310.6 RUS90342.1 - 0.12 12.6 14.2 13 6.0 0.3 4.5 1 1 3 4 4 4 0 Fibronectin type III-like domain DUF3416 PF11896.8 RUS90342.1 - 6.4 7.0 19.0 18 5.5 0.8 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF3416) Utp12 PF04003.12 RUS90343.1 - 1.8e-19 70.0 0.1 2.7e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 RUS90343.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal HpcH_HpaI PF03328.14 RUS90344.1 - 0.0009 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF4537 PF15057.6 RUS90345.1 - 6.6e-29 100.4 0.0 2.4e-28 98.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) VWA_3 PF13768.6 RUS90345.1 - 1.7e-09 37.8 0.0 4.1e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RUS90345.1 - 6.9e-05 23.2 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS90345.1 - 0.00017 22.2 0.0 0.00066 20.3 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Tudor_3 PF18115.1 RUS90345.1 - 0.012 15.5 2.2 0.78 9.6 0.0 2.9 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain WDCP PF15390.6 RUS90346.1 - 2.7e-42 145.1 3.1 2.8e-27 95.4 0.5 3.3 2 1 1 3 3 3 3 WD repeat and coiled-coil-containing protein family Ashwin PF15323.6 RUS90347.1 - 6.1e-17 62.4 10.8 1.7e-16 60.9 10.8 1.8 1 1 0 1 1 1 1 Developmental protein SCP-1 PF05483.12 RUS90348.1 - 2.1e-09 36.0 148.0 1.2e-08 33.5 146.3 3.2 1 1 1 2 2 2 1 Synaptonemal complex protein 1 (SCP-1) ATG16 PF08614.11 RUS90348.1 - 0.11 12.7 174.7 0.055 13.7 9.5 8.7 1 1 7 8 8 8 0 Autophagy protein 16 (ATG16) MPC PF03650.13 RUS90349.1 - 1.2e-38 131.6 0.1 1.5e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Vta1 PF04652.16 RUS90350.1 - 1.7e-50 170.7 0.8 2e-50 170.5 0.8 1.0 1 0 0 1 1 1 1 Vta1 like Glyco_hydro_49 PF03718.13 RUS90351.1 - 0.11 12.5 4.9 2.4 8.2 1.1 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 49 AROS PF15684.5 RUS90351.1 - 0.33 11.5 3.9 14 6.3 0.5 2.4 1 1 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 CW_binding_1 PF01473.20 RUS90352.1 - 1.4e-09 37.7 0.0 4.1e+02 1.6 0.0 10.9 12 0 0 12 12 12 0 Putative cell wall binding repeat BNR PF02012.20 RUS90352.1 - 1.5e-09 36.4 52.5 30 5.2 0.0 14.6 15 0 0 15 15 15 11 BNR/Asp-box repeat DUF4099 PF13351.6 RUS90352.1 - 4.6e-05 23.6 0.1 85 3.5 0.0 5.9 1 1 7 8 8 8 0 Protein of unknown function (DUF4099) WHH PF14414.6 RUS90352.1 - 0.023 14.5 105.8 1.7 8.6 0.6 14.1 1 1 13 14 14 14 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH VIGSSK PF14773.6 RUS90352.1 - 0.041 14.0 16.0 66 3.7 0.1 6.2 2 2 6 9 9 9 0 Helicase-associated putative binding domain, C-terminal RNase_E_G PF10150.9 RUS90353.1 - 0.34 10.3 0.8 0.43 9.9 0.8 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family UvsY PF11056.8 RUS90354.1 - 1.6e-05 25.2 1.5 6.9 7.0 0.2 5.2 1 1 2 3 3 3 3 Recombination, repair and ssDNA binding protein UvsY MSG PF02349.15 RUS90354.1 - 0.0031 17.7 47.0 0.13 12.5 6.1 4.5 1 1 2 3 3 3 2 Major surface glycoprotein Serine_rich PF08824.10 RUS90354.1 - 0.16 12.0 0.0 11 6.0 0.0 2.8 1 1 1 2 2 2 0 Serine rich protein interaction domain SicP-binding PF09119.10 RUS90354.1 - 0.94 9.5 10.8 87 3.2 0.2 5.2 1 1 2 3 3 3 0 SicP binding FdsD PF11390.8 RUS90354.1 - 2.7 8.4 10.8 1e+02 3.3 0.1 5.2 2 1 4 6 6 6 0 NADH-dependant formate dehydrogenase delta subunit FdsD LRR_8 PF13855.6 RUS90356.1 - 5.7e-11 42.0 1.9 3e-10 39.7 0.8 1.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RUS90356.1 - 0.00095 19.5 3.5 0.054 13.9 0.3 2.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS90356.1 - 0.013 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF268 PF03269.14 RUS90356.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 Engrail_1_C_sig PF10525.9 RUS90358.1 - 0.087 12.1 0.4 10 5.5 0.1 2.4 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain Defensin_int PF17858.1 RUS90358.1 - 0.9 9.6 3.4 4.2 7.4 0.8 2.3 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide GPS PF01825.21 RUS90359.1 - 2e-14 53.8 3.7 3.4e-14 53.1 3.7 1.4 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 RUS90359.1 - 2.1e-12 46.9 0.7 2.7e-12 46.5 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TraL PF07178.11 RUS90359.1 - 0.027 14.9 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 TraL protein Frizzled PF01534.17 RUS90359.1 - 0.053 12.6 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Urate_ox_N PF06181.11 RUS90359.1 - 0.065 12.6 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal Toxin_29 PF08116.11 RUS90361.1 - 0.53 10.3 12.1 53 3.9 0.0 5.4 4 1 1 5 5 5 0 PhTx neurotoxin family BIR PF00653.21 RUS90362.1 - 2.7e-39 133.6 0.0 5.7e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 RUS90362.1 - 6.6e-06 26.2 0.0 0.17 12.0 0.0 3.1 2 1 1 3 3 3 2 C3HC zinc finger-like OTT_1508_deam PF14441.6 RUS90362.1 - 0.007 16.4 0.3 3.2 7.8 0.0 2.4 2 0 0 2 2 2 2 OTT_1508-like deaminase EIIA-man PF03610.16 RUS90362.1 - 0.11 12.7 0.2 0.19 12.0 0.2 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component Ras PF00071.22 RUS90365.1 - 5.3e-18 65.1 0.0 2.3e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RUS90365.1 - 8.9e-16 58.2 0.0 1.2e-14 54.5 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS90365.1 - 4.2e-13 49.1 0.0 3.4e-10 39.7 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS90365.1 - 2.1e-07 31.0 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS90365.1 - 0.00042 19.8 0.0 0.001 18.5 0.0 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RUS90365.1 - 0.0035 16.9 0.0 0.51 9.8 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 RUS90365.1 - 0.004 16.9 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RUS90365.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 RUS90365.1 - 0.11 11.7 0.1 2.2 7.4 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit Collagen_mid PF15984.5 RUS90366.1 - 0.062 13.0 8.4 0.093 12.5 8.4 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region Rib_recp_KP_reg PF05104.12 RUS90366.1 - 0.89 10.6 10.7 1.7 9.7 10.7 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region CRAM_rpt PF07016.11 RUS90367.1 - 3.8e-12 45.5 20.3 0.0072 16.1 0.4 5.8 3 3 5 8 8 8 8 Cysteine-rich acidic integral membrane protein precursor zf_CCCH_4 PF18345.1 RUS90367.1 - 0.02 14.9 14.9 49 4.2 0.0 6.8 8 0 0 8 8 8 0 Zinc finger domain Squash PF00299.18 RUS90367.1 - 0.034 14.2 15.2 33 4.6 0.2 6.4 3 3 2 5 5 5 0 Squash family serine protease inhibitor Fucokinase PF07959.12 RUS90367.1 - 0.31 9.9 2.4 3.4 6.5 0.2 2.0 1 1 1 2 2 2 0 L-fucokinase PepSY_2 PF13670.6 RUS90368.1 - 9.1 6.4 8.5 5.9 7.0 6.3 1.8 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain NS3_envE PF02723.14 RUS90369.1 - 0.027 14.5 7.4 0.027 14.5 7.4 1.9 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF929 PF06053.11 RUS90369.1 - 0.083 12.2 3.4 0.069 12.4 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF929) DUF2207 PF09972.9 RUS90369.1 - 0.17 10.6 0.2 0.18 10.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5527 PF17665.1 RUS90369.1 - 4.9 6.7 6.5 18 4.9 3.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5527) RecT PF03837.14 RUS90370.1 - 0.095 12.2 0.9 12 5.3 0.1 2.5 2 0 0 2 2 2 0 RecT family MoaF_C PF17409.2 RUS90372.1 - 0.29 10.8 1.8 0.57 9.9 0.2 2.0 2 0 0 2 2 2 0 MoaF C-terminal domain DUF4139 PF13598.6 RUS90374.1 - 3.2e-52 177.3 0.4 5.1e-52 176.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 RUS90374.1 - 7.1e-19 68.1 3.4 1.7e-18 66.8 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) IFP_35_N PF07334.13 RUS90374.1 - 0.02 15.0 0.5 0.06 13.4 0.5 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Seryl_tRNA_N PF02403.22 RUS90374.1 - 0.14 12.4 6.2 0.44 10.8 1.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 RUS90374.1 - 0.27 11.4 6.1 0.97 9.6 1.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF5320 PF17253.2 RUS90374.1 - 1.1 10.3 2.8 3.6 8.7 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Spc24 PF08286.11 RUS90374.1 - 2.5 8.4 6.0 1.3 9.3 1.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4559 PF15112.6 RUS90374.1 - 6.8 6.3 9.6 0.84 9.3 4.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) AAA PF00004.29 RUS90376.1 - 1.6e-34 119.2 0.0 2.8e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS90376.1 - 1.2e-05 25.8 1.2 0.0001 22.8 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RUS90376.1 - 2.4e-05 24.2 0.0 7.6e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS90376.1 - 0.00021 21.5 0.0 0.00058 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 RUS90376.1 - 0.0003 20.1 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 RUS90376.1 - 0.00034 20.3 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 RUS90376.1 - 0.00035 20.9 0.0 0.00074 19.9 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 RUS90376.1 - 0.0005 20.4 0.5 0.013 15.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RUS90376.1 - 0.00052 20.6 0.0 0.001 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RUS90376.1 - 0.0006 19.8 0.0 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RUS90376.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RUS90376.1 - 0.0023 18.1 0.0 0.0048 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RUS90376.1 - 0.0027 17.4 0.1 0.0097 15.7 0.0 1.9 2 1 1 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 RUS90376.1 - 0.0031 17.4 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 RUS90376.1 - 0.0036 16.7 0.1 0.025 14.0 0.0 2.4 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 RUS90376.1 - 0.0043 17.1 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RUS90376.1 - 0.0053 17.0 0.1 0.021 15.1 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 RUS90376.1 - 0.0054 17.2 0.1 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RUS90376.1 - 0.015 14.9 0.0 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 RUS90376.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RUS90376.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RUS90376.1 - 0.1 11.9 0.0 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.11 RUS90376.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RUS90376.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 RUS90376.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 7TM_GPCR_Srw PF10324.9 RUS90377.1 - 2.4e-13 50.1 10.7 3.7e-13 49.4 10.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS90377.1 - 3.4e-10 39.7 12.5 4.6e-10 39.3 12.4 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS90377.1 - 6.7e-10 39.0 10.3 6.7e-10 39.0 10.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ODV-E18 PF10717.9 RUS90377.1 - 1.9 8.4 4.5 18 5.2 0.0 2.8 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Ribosomal_L21p PF00829.21 RUS90378.1 - 3.7e-21 75.3 0.0 5.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Sigma70_ECF PF07638.11 RUS90379.1 - 0.0026 17.7 0.3 0.0054 16.6 0.3 1.5 1 0 0 1 1 1 1 ECF sigma factor Adaptin_N PF01602.20 RUS90380.1 - 8.2e-42 143.4 9.9 8.6e-41 140.1 9.9 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RUS90380.1 - 6.8e-20 71.7 6.0 1.4e-18 67.5 0.1 4.0 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RUS90380.1 - 0.0021 18.4 3.1 0.011 16.1 0.4 3.4 3 1 1 4 4 4 1 HEAT repeats Ndr PF03096.14 RUS90380.1 - 0.0032 16.2 0.2 0.013 14.2 0.1 2.0 1 1 0 1 1 1 1 Ndr family HEAT PF02985.22 RUS90380.1 - 0.0057 16.8 10.0 2.8 8.4 0.3 5.5 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 RUS90380.1 - 0.066 13.3 1.8 2.9 8.0 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2626 PF11117.8 RUS90381.1 - 0.00043 20.9 5.6 0.49 11.2 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2626) LRR_3 PF07725.12 RUS90381.1 - 0.016 15.0 0.1 40 4.3 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat Claudin_3 PF06653.11 RUS90382.1 - 2e-09 37.6 4.8 2.4e-09 37.4 4.8 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Claudin_2 PF13903.6 RUS90382.1 - 8.9e-06 25.6 4.9 8.9e-06 25.6 4.9 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS90382.1 - 1.2e-05 25.2 8.2 2.6e-05 24.1 8.2 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 RUS90382.1 - 0.0056 16.5 2.1 0.0056 16.5 2.1 1.7 1 1 1 2 2 2 1 Amastin surface glycoprotein DUF308 PF03729.13 RUS90382.1 - 0.01 16.1 1.0 0.01 16.1 1.0 3.6 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) DUF4905 PF16248.5 RUS90382.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) UPF0093 PF03653.13 RUS90382.1 - 0.061 13.5 0.5 2 8.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0093) DUF4064 PF13273.6 RUS90382.1 - 0.27 11.6 11.1 0.055 13.7 2.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4149 PF13664.6 RUS90382.1 - 0.38 11.1 3.9 1.6 9.1 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF2975 PF11188.8 RUS90382.1 - 7.5 6.4 9.7 0.21 11.5 1.9 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) RVT_1 PF00078.27 RUS90383.1 - 8.1e-30 104.0 0.5 1.3e-29 103.3 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) I-set PF07679.16 RUS90384.1 - 2.1e-96 316.2 0.0 8.8e-17 61.0 0.0 8.5 8 0 0 8 8 8 7 Immunoglobulin I-set domain Pkinase PF00069.25 RUS90384.1 - 6.6e-70 235.5 0.0 1e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 RUS90384.1 - 1.3e-65 218.0 9.4 4.6e-12 46.4 0.1 8.0 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 RUS90384.1 - 1e-49 166.7 6.4 5e-09 36.2 0.2 7.0 6 0 0 6 6 6 6 Immunoglobulin domain Pkinase_Tyr PF07714.17 RUS90384.1 - 2.6e-36 125.2 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 RUS90384.1 - 6.7e-33 112.9 9.5 9.5e-08 32.3 0.0 7.7 8 0 0 8 8 8 6 Immunoglobulin domain V-set PF07686.17 RUS90384.1 - 2.7e-21 75.8 6.9 2.3e-05 24.5 0.0 9.9 7 4 0 7 7 7 3 Immunoglobulin V-set domain fn3 PF00041.21 RUS90384.1 - 2.1e-13 50.4 0.0 7.5e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain C2-set_2 PF08205.12 RUS90384.1 - 6.7e-12 45.3 4.8 0.27 11.3 0.0 6.4 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS90384.1 - 1.5e-06 27.7 0.3 0.4 10.3 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin domain C1-set PF07654.15 RUS90384.1 - 8.2e-06 26.1 0.7 1.5 9.3 0.0 5.1 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 RUS90384.1 - 1.1e-05 25.4 0.1 14 5.8 0.0 4.9 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 RUS90384.1 - 0.001 19.3 0.6 4.7 7.6 0.0 5.4 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Kdo PF06293.14 RUS90384.1 - 0.0022 17.4 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS90384.1 - 0.01 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 RUS90384.1 - 0.039 13.9 0.1 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family fn3 PF00041.21 RUS90385.1 - 3.7e-11 43.2 0.3 1.1e-10 41.7 0.3 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS90385.1 - 0.0009 19.8 0.1 0.0029 18.2 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 RUS90387.1 - 0 1823.6 114.0 5.2e-18 65.2 0.3 40.5 40 0 0 40 40 40 40 Fibronectin type III domain I-set PF07679.16 RUS90387.1 - 1e-274 887.7 11.3 2e-21 75.8 0.0 19.2 18 0 0 18 18 16 14 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90387.1 - 8.8e-184 596.6 6.6 2.4e-14 53.7 0.0 18.1 18 0 0 18 18 16 14 Immunoglobulin domain ig PF00047.25 RUS90387.1 - 3.4e-114 373.3 14.5 8e-13 48.4 0.1 15.6 15 0 0 15 15 14 13 Immunoglobulin domain Ig_2 PF13895.6 RUS90387.1 - 2.8e-111 364.0 12.3 4.4e-11 43.0 0.0 16.3 16 0 0 16 16 15 13 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 RUS90387.1 - 3.7e-81 267.8 79.5 0.021 15.4 0.0 38.1 40 0 0 40 40 36 16 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 RUS90387.1 - 4.2e-70 236.1 0.0 7e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Tissue_fac PF01108.17 RUS90387.1 - 1.3e-59 198.7 18.1 0.11 12.4 0.1 32.1 34 0 0 34 34 33 9 Tissue factor fn3_4 PF16794.5 RUS90387.1 - 1e-53 179.5 0.0 0.0097 15.8 0.0 27.2 28 0 0 28 28 26 9 Fibronectin-III type domain V-set PF07686.17 RUS90387.1 - 4.2e-49 165.3 30.2 4.2e-05 23.7 0.1 21.3 15 8 0 15 15 15 10 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS90387.1 - 9.2e-36 121.8 7.3 0.0067 16.5 0.1 14.8 14 0 0 14 14 14 8 CD80-like C2-set immunoglobulin domain Pkinase_Tyr PF07714.17 RUS90387.1 - 1.7e-35 122.6 0.0 3.2e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2369 PF10179.9 RUS90387.1 - 1.1e-30 105.9 0.0 3.8 8.0 0.0 21.7 26 1 0 26 26 19 3 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 RUS90387.1 - 1.1e-18 67.2 12.9 2.1 8.6 0.0 19.1 23 0 0 23 23 18 2 Fibronectin type III domain Ig_5 PF16681.5 RUS90387.1 - 1.5e-16 60.6 11.4 0.033 14.6 0.0 11.5 12 0 0 12 12 11 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS90387.1 - 1.2e-13 51.0 8.3 0.21 11.9 0.1 9.7 9 1 0 9 9 8 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS90387.1 - 2.6e-13 49.3 0.0 0.48 10.0 0.0 8.1 7 0 0 7 7 7 3 Immunoglobulin domain PhoD_N PF16655.5 RUS90387.1 - 2.1e-11 44.2 13.9 15 6.2 0.0 18.5 24 0 0 24 24 17 0 PhoD-like phosphatase, N-terminal domain SusE PF14292.6 RUS90387.1 - 4.5e-11 42.9 55.7 0.012 15.8 0.0 20.6 26 0 0 26 26 22 4 SusE outer membrane protein Ig_C17orf99 PF17736.1 RUS90387.1 - 7.5e-09 35.5 0.2 0.049 13.7 0.0 7.4 9 0 0 9 9 5 2 C17orf99 Ig domain C1-set PF07654.15 RUS90387.1 - 1.1e-08 35.4 3.7 0.26 11.7 0.0 8.5 10 0 0 10 10 7 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 RUS90387.1 - 1.1e-08 35.0 13.6 8.9 6.4 0.0 10.7 11 0 0 11 11 11 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 RUS90387.1 - 1.3e-08 35.0 5.9 7.5 6.8 0.0 10.3 10 0 0 10 10 8 0 Natural killer cell receptor 2B4 CRISPR_assoc PF08798.11 RUS90387.1 - 3.8e-08 33.7 2.2 22 5.1 0.0 10.0 13 0 0 13 13 10 0 CRISPR associated protein Reeler PF02014.16 RUS90387.1 - 1.7e-07 32.1 27.6 1.2e+02 3.4 0.0 20.9 28 2 1 29 29 20 0 Reeler domain Herpes_gE PF02480.16 RUS90387.1 - 2.4e-07 29.9 0.2 0.28 9.9 0.0 6.5 7 0 0 7 7 7 1 Alphaherpesvirus glycoprotein E CopC PF04234.12 RUS90387.1 - 0.0051 17.8 0.1 2.4 9.2 0.0 6.1 3 1 0 3 3 1 1 CopC domain F5_F8_type_C PF00754.25 RUS90387.1 - 0.013 15.6 48.1 1.5 9.0 0.0 13.5 17 0 0 17 17 13 0 F5/8 type C domain Kinase-like PF14531.6 RUS90387.1 - 0.029 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 RUS90387.1 - 0.033 13.5 0.1 0.072 12.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2-set PF05790.15 RUS90387.1 - 0.14 12.4 5.0 0.53 10.5 0.1 4.6 5 0 0 5 5 4 0 Immunoglobulin C2-set domain DUF2393 PF09624.10 RUS90387.1 - 0.27 11.2 0.4 36 4.3 0.0 4.5 6 0 0 6 6 4 0 Protein of unknown function (DUF2393) BNR PF02012.20 RUS90387.1 - 0.37 11.0 7.3 69 4.1 0.2 5.4 3 0 0 3 3 3 0 BNR/Asp-box repeat fn3 PF00041.21 RUS90388.1 - 1.8e-19 69.9 0.2 7.9e-11 42.2 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS90388.1 - 7.1e-09 36.1 0.4 0.00063 20.3 0.2 2.1 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RUS90388.1 - 0.0054 17.1 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 RUS90388.1 - 0.054 14.0 0.0 6.7 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF1329 PF07044.11 RUS90388.1 - 0.06 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) DUF4044 PF13253.6 RUS90388.1 - 0.25 10.9 2.7 0.88 9.1 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4044) I-set PF07679.16 RUS90389.1 - 1.9e-64 213.8 3.9 4.6e-13 49.1 0.0 6.1 4 2 2 6 6 6 6 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90389.1 - 8.4e-38 128.8 1.2 7.2e-08 32.9 0.1 6.1 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 RUS90389.1 - 1.2e-25 89.5 7.6 3.4e-09 36.7 0.2 6.1 5 1 1 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 RUS90389.1 - 3.1e-18 65.9 0.7 3.9e-05 23.9 0.0 5.8 5 1 1 6 6 6 4 Immunoglobulin domain V-set PF07686.17 RUS90389.1 - 1.4e-12 47.8 4.5 0.11 12.7 0.0 7.6 5 2 1 6 6 6 3 Immunoglobulin V-set domain C1-set PF07654.15 RUS90389.1 - 4.3e-08 33.4 2.3 0.4 11.1 0.1 5.7 5 1 0 5 5 5 2 Immunoglobulin C1-set domain BiPBP_C PF06832.12 RUS90389.1 - 1.6e-06 28.0 0.0 0.0095 16.0 0.0 4.1 4 1 1 5 5 5 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 RUS90389.1 - 0.00013 22.2 5.0 5.3 7.4 0.1 5.4 6 1 0 6 6 6 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 RUS90389.1 - 0.00018 21.5 1.2 1.5 9.0 0.0 4.5 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain C6 PF01681.17 RUS90389.1 - 0.003 18.1 2.5 0.29 11.7 0.7 3.6 3 1 0 3 3 3 1 C6 domain Cadherin-like PF12733.7 RUS90389.1 - 0.044 14.3 3.2 4.8 7.8 0.4 3.7 3 1 0 4 4 4 0 Cadherin-like beta sandwich domain DUF4923 PF16270.5 RUS90389.1 - 0.049 13.5 0.2 1.1 9.1 0.2 2.8 2 1 0 2 2 2 0 Lipocalin-like domain (DUF4923) DUF3284 PF11687.8 RUS90389.1 - 0.11 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) HSP33 PF01430.19 RUS90389.1 - 0.14 11.6 0.3 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 Hsp33 protein Glyco_hydro_5_C PF18564.1 RUS90389.1 - 0.15 12.7 0.2 1.7 9.2 0.0 2.6 3 0 0 3 3 3 0 Glycoside hydrolase family 5 C-terminal domain I-set PF07679.16 RUS90390.1 - 0 1416.6 60.4 2.4e-23 82.0 0.0 27.2 27 0 0 27 27 27 26 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90390.1 - 2.3e-271 877.3 25.3 3e-13 50.1 0.0 27.5 26 0 0 26 26 26 26 Immunoglobulin domain ig PF00047.25 RUS90390.1 - 1e-167 544.8 46.8 8.4e-12 45.1 0.0 26.5 26 0 0 26 26 26 25 Immunoglobulin domain Ig_2 PF13895.6 RUS90390.1 - 1.6e-146 476.9 14.7 2.2e-09 37.5 0.0 25.3 26 0 0 26 26 25 24 Immunoglobulin domain V-set PF07686.17 RUS90390.1 - 1e-53 180.1 40.4 0.0074 16.4 0.0 28.5 24 10 1 25 25 25 12 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS90390.1 - 1.7e-37 127.4 19.2 0.068 13.2 0.0 21.4 22 0 0 22 22 22 7 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 RUS90390.1 - 1.7e-10 40.3 0.3 0.95 9.1 0.1 7.0 8 0 0 8 8 8 3 Immunoglobulin domain Receptor_2B4 PF11465.8 RUS90390.1 - 9.1e-10 38.7 4.9 0.93 9.7 0.0 11.2 15 0 0 15 15 13 2 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 RUS90390.1 - 1e-08 35.1 13.7 8.6 6.5 0.0 13.6 17 0 0 17 17 17 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS90390.1 - 1.2e-06 28.8 31.0 0.59 10.5 0.0 14.7 18 0 0 18 18 17 2 Immunoglobulin C1-set domain IQ PF00612.27 RUS90390.1 - 7.8e-05 22.1 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF11 PF01345.18 RUS90390.1 - 0.005 17.1 0.9 0.005 17.1 0.9 9.2 10 1 0 10 10 8 1 Domain of unknown function DUF11 SLY PF12485.8 RUS90390.1 - 0.21 12.3 4.4 2.7 8.7 4.4 3.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein CDC13_N PF16853.5 RUS90391.1 - 0.1 12.1 1.5 0.11 12.0 1.5 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus I-set PF07679.16 RUS90392.1 - 8.4e-11 41.8 0.1 1.4e-09 37.9 0.0 3.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90392.1 - 1.6e-07 31.8 0.5 6.8e-06 26.6 0.0 3.5 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS90392.1 - 0.0003 21.1 0.0 0.001 19.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS90392.1 - 0.0089 16.2 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 RUS90392.1 - 0.02 14.9 0.4 0.13 12.3 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Glyco_hydro_5_C PF18564.1 RUS90392.1 - 5.6 7.6 6.9 2 9.0 0.7 3.0 2 1 0 3 3 3 0 Glycoside hydrolase family 5 C-terminal domain FlgT_C PF16538.5 RUS90392.1 - 8.4 7.0 8.7 5.7 7.5 0.1 3.7 3 0 0 3 3 3 0 Flagellar assembly protein T, C-terminal domain I-set PF07679.16 RUS90393.1 - 5.4e-18 64.8 0.0 8.4e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90393.1 - 1.5e-14 54.3 0.0 2.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS90393.1 - 5.5e-12 45.7 0.0 1.1e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 RUS90393.1 - 2.4e-07 31.0 0.0 3.2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS90393.1 - 0.0021 18.2 0.0 0.015 15.5 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS90393.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 RUS90394.1 - 3.5e-49 164.8 0.0 9.8e-23 80.0 0.0 3.0 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90394.1 - 3.7e-32 110.8 0.4 1.4e-14 54.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS90394.1 - 1.8e-23 82.7 0.0 1.7e-12 47.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 RUS90394.1 - 1.1e-15 57.6 0.0 1.4e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 RUS90394.1 - 3.1e-10 40.2 0.2 0.37 11.0 0.0 4.9 3 2 2 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS90394.1 - 6.4e-05 23.0 0.3 0.33 11.0 0.0 3.0 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 RUS90394.1 - 0.11 11.2 0.0 0.46 9.2 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.16 RUS90395.1 - 1.5e-16 60.2 0.0 2.2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90395.1 - 1.6e-09 38.2 0.0 2.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS90395.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS90395.1 - 7.3e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS90395.1 - 0.0002 21.5 0.1 0.01 16.0 0.0 2.3 1 1 2 3 3 3 1 Immunoglobulin V-set domain Ig_4 PF16680.5 RUS90395.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.7 1 1 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 RUS90396.1 - 2e-257 832.2 0.0 1.1e-22 79.9 0.0 12.3 12 0 0 12 12 12 12 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90396.1 - 1.4e-169 551.1 0.0 1.2e-13 51.5 0.1 12.6 12 0 0 12 12 12 12 Immunoglobulin domain Ig_2 PF13895.6 RUS90396.1 - 9.2e-97 317.5 0.3 1.1e-09 38.5 0.1 12.5 12 0 0 12 12 12 12 Immunoglobulin domain ig PF00047.25 RUS90396.1 - 1.7e-92 303.7 0.0 1.6e-11 44.2 0.0 12.4 12 0 0 12 12 12 12 Immunoglobulin domain V-set PF07686.17 RUS90396.1 - 1.9e-32 111.7 9.0 0.016 15.3 0.0 16.9 12 7 0 12 12 12 9 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS90396.1 - 5.9e-30 103.2 4.4 0.15 12.2 0.0 13.4 13 2 0 13 13 13 7 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 RUS90396.1 - 2e-13 50.5 0.0 5.4 7.5 0.0 10.6 11 1 0 11 11 11 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 RUS90396.1 - 3.5e-07 30.4 0.0 7.8 6.8 0.0 8.0 10 0 0 10 10 10 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS90396.1 - 4.3e-07 29.4 0.0 0.061 12.9 0.0 5.8 7 0 0 7 7 7 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 RUS90396.1 - 0.00012 21.8 0.1 0.45 10.3 0.1 5.6 7 0 0 7 7 7 1 Adenovirus E3 region protein CR1 Spectrin PF00435.21 RUS90398.1 - 4.7e-41 139.5 81.1 2.1e-09 37.8 0.1 11.2 7 3 4 11 11 11 10 Spectrin repeat I-set PF07679.16 RUS90398.1 - 1.8e-31 108.0 0.1 7.7e-17 61.1 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90398.1 - 1.7e-20 73.4 1.8 2e-11 44.3 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 RUS90398.1 - 4.7e-12 46.1 0.1 2.8e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS90398.1 - 1.1e-07 31.9 0.2 0.00016 21.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS90398.1 - 3.4e-05 24.0 0.4 0.28 11.4 0.1 4.7 3 2 0 3 3 3 1 Immunoglobulin V-set domain DUF948 PF06103.11 RUS90398.1 - 0.47 10.7 25.2 5.6 7.3 0.4 8.1 8 0 0 8 8 8 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 RUS90399.1 - 6.5e-05 23.4 1.9 0.0004 20.8 0.4 7.1 7 0 0 7 7 7 4 Spectrin repeat Rx_N PF18052.1 RUS90399.1 - 0.15 12.4 5.2 0.17 12.2 0.6 3.3 3 0 0 3 3 3 0 Rx N-terminal domain CRAL_TRIO_2 PF13716.6 RUS90399.1 - 0.19 11.9 0.0 7.7 6.7 0.0 3.0 2 1 0 3 3 3 0 Divergent CRAL/TRIO domain FAM195 PF14799.6 RUS90399.1 - 3.5 8.0 12.6 24 5.3 12.6 2.5 1 0 0 1 1 1 0 FAM195 family FKBP_C PF00254.28 RUS90400.1 - 2.7e-28 98.1 0.0 3.4e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Spc7 PF08317.11 RUS90401.1 - 0.0031 16.4 13.5 0.0031 16.4 13.5 3.9 1 1 3 4 4 4 2 Spc7 kinetochore protein CENP-H PF05837.12 RUS90401.1 - 0.0072 16.7 1.6 0.0072 16.7 1.6 4.6 2 2 2 4 4 4 1 Centromere protein H (CENP-H) ABC_tran_CTD PF16326.5 RUS90401.1 - 0.019 15.2 1.8 0.019 15.2 1.8 4.8 3 1 1 4 4 4 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 RUS90401.1 - 0.055 13.9 4.0 9.1 6.8 0.5 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 RUS90401.1 - 0.072 12.4 22.4 0.19 11.1 4.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) COG5 PF10392.9 RUS90401.1 - 0.18 12.0 5.3 0.8 9.9 0.3 3.0 2 2 0 2 2 2 0 Golgi transport complex subunit 5 DUF948 PF06103.11 RUS90401.1 - 0.61 10.4 3.3 12 6.2 0.3 3.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Myb_DNA-bind_5 PF13873.6 RUS90401.1 - 1.5 9.0 7.7 0.19 11.8 0.4 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Filament PF00038.21 RUS90401.1 - 4.2 6.9 37.9 0.015 14.9 9.5 3.8 1 1 3 4 4 4 0 Intermediate filament protein Syntaxin_2 PF14523.6 RUS90401.1 - 4.8 7.6 17.2 1.7 9.1 1.7 3.8 4 1 0 4 4 4 0 Syntaxin-like protein DivIC PF04977.15 RUS90401.1 - 6.5 6.6 16.6 2.4 8.0 0.1 5.2 3 1 3 6 6 6 0 Septum formation initiator DUF1192 PF06698.11 RUS90401.1 - 6.6 6.9 10.3 1.4 9.0 0.1 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) Homeodomain PF00046.29 RUS90402.1 - 1.8e-23 82.1 1.3 4e-23 81.0 1.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS90402.1 - 0.00011 22.1 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 RUS90403.1 - 2.6e-06 27.2 0.1 1.5e-05 24.7 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 RUS90403.1 - 3.8e-05 23.5 16.4 4.5e-05 23.2 2.4 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS90403.1 - 0.093 12.8 11.7 0.97 9.6 3.1 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 RUS90403.1 - 1 9.3 12.2 1.5 8.7 3.4 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger Exostosin PF03016.15 RUS90404.1 - 0.075 12.2 2.5 0.095 11.9 2.5 1.2 1 0 0 1 1 1 0 Exostosin family BPL_N PF09825.9 RUS90404.1 - 2.1 7.3 9.3 2.7 7.0 9.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FUSC PF04632.12 RUS90404.1 - 4.8 5.6 4.4 5.4 5.4 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1788 PF08747.11 RUS90404.1 - 8.1 6.5 7.1 2 8.4 3.1 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1788) RabGAP-TBC PF00566.18 RUS90405.1 - 1.2e-46 159.1 0.6 5.2e-46 157.0 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 RUS90405.1 - 1.8e-37 127.7 0.1 6.2e-22 77.6 0.0 2.5 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 RUS90405.1 - 0.00045 19.6 0.4 0.0026 17.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS90405.1 - 0.0033 17.2 0.0 0.017 15.0 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 RUS90405.1 - 0.079 12.8 0.2 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS90405.1 - 0.12 11.9 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 EF hand Ldl_recept_a PF00057.18 RUS90406.1 - 1.4e-08 34.8 15.5 2.2e-08 34.2 15.5 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 RUS90406.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.6 1 1 0 1 1 1 1 CUB domain CUB PF00431.20 RUS90407.1 - 2.6e-09 37.4 0.1 2.1e-06 28.0 0.6 2.2 2 0 0 2 2 2 2 CUB domain Ntox43 PF15537.6 RUS90407.1 - 0.025 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 43 DUF865 PF05906.11 RUS90407.1 - 0.13 12.0 1.4 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) SDA1 PF05285.12 RUS90408.1 - 0.0015 18.0 42.0 0.007 15.8 32.5 2.2 2 0 0 2 2 2 2 SDA1 Nop14 PF04147.12 RUS90408.1 - 0.0021 16.4 34.4 0.0021 16.4 34.4 2.0 2 0 0 2 2 2 2 Nop14-like family CDC45 PF02724.14 RUS90408.1 - 0.044 12.1 38.0 0.049 11.9 30.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 RUS90408.1 - 0.06 11.5 50.4 0.012 13.8 38.5 2.2 2 0 0 2 2 2 0 DNA polymerase phi Mpp10 PF04006.12 RUS90408.1 - 0.16 10.4 51.6 0.063 11.7 38.2 2.1 2 0 0 2 2 2 0 Mpp10 protein Vfa1 PF08432.10 RUS90408.1 - 0.43 10.9 27.4 0.47 10.8 18.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 RUS90408.1 - 0.52 9.2 54.0 0.069 12.1 39.1 2.2 2 0 0 2 2 2 0 Paf1 Serinc PF03348.15 RUS90408.1 - 1.3 7.9 9.5 0.15 11.0 4.0 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) Connexin PF00029.19 RUS90408.1 - 3.6 7.3 23.0 5.5 6.7 14.7 2.5 2 0 0 2 2 2 0 Connexin Forkhead PF00250.18 RUS90409.1 - 1.4e-36 124.6 0.0 3.5e-36 123.3 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain CAP_N PF01213.19 RUS90409.1 - 1.4 8.4 4.3 3 7.3 4.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TFIIA PF03153.13 RUS90410.1 - 4.1 7.3 29.7 5.8 6.8 29.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM_like_2 PF16357.5 RUS90410.1 - 9.4 6.1 7.8 2.2 8.2 3.4 2.1 2 0 0 2 2 2 0 Putative PepSY_TM-like Pox_I5 PF04713.12 RUS90412.1 - 0.07 13.2 7.0 6.8 6.8 0.4 3.8 2 2 2 4 4 4 0 Poxvirus protein I5 Ribonuc_2-5A PF06479.12 RUS90413.1 - 2.7e-11 43.7 0.0 3.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 RUS90413.1 - 0.00075 18.9 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ldl_recept_a PF00057.18 RUS90414.1 - 1.7e-07 31.3 7.3 3.5e-07 30.3 7.3 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB PF00431.20 RUS90414.1 - 0.00068 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 CUB domain NicO PF03824.16 RUS90414.1 - 0.03 13.7 2.2 0.05 12.9 2.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Epiglycanin_C PF14654.6 RUS90414.1 - 0.035 14.1 0.7 0.09 12.8 0.7 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region MacB_PCD PF12704.7 RUS90414.1 - 0.065 13.6 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain EphA2_TM PF14575.6 RUS90414.1 - 0.27 12.1 0.1 0.27 12.1 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain adh_short PF00106.25 RUS90415.1 - 7.4e-50 169.1 0.0 1e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS90415.1 - 6.2e-30 104.5 0.0 8.5e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS90415.1 - 7e-11 42.4 0.3 1e-10 41.8 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RUS90415.1 - 0.00012 22.1 0.1 0.0002 21.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 RUS90415.1 - 0.014 15.3 0.1 0.044 13.7 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 RUS90415.1 - 0.029 13.9 0.1 0.078 12.4 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thioredoxin_8 PF13905.6 RUS90415.1 - 0.071 13.4 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like NmrA PF05368.13 RUS90415.1 - 0.12 11.9 0.4 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family GCV_H PF01597.19 RUS90416.1 - 6.9e-38 129.3 0.1 8.2e-38 129.0 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein SYS1 PF09801.9 RUS90417.1 - 4.1e-39 134.0 10.9 4.7e-39 133.8 10.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network NADH_B2 PF14813.6 RUS90417.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.5 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pollen_Ole_e_I PF01190.17 RUS90419.1 - 0.031 14.6 1.2 0.05 14.0 1.2 1.3 1 0 0 1 1 1 0 Pollen proteins Ole e I like MARVEL PF01284.23 RUS90420.1 - 1e-27 97.0 7.9 1.2e-27 96.7 7.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain NB PF04159.13 RUS90420.1 - 0.0024 17.8 0.5 0.0042 17.1 0.1 1.6 2 0 0 2 2 2 1 NB glycoprotein zf-C3HC4_3 PF13920.6 RUS90421.1 - 9.8e-07 28.5 11.3 9.8e-07 28.5 11.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS90421.1 - 0.0013 18.6 11.5 0.0013 18.6 11.5 3.4 4 0 0 4 4 4 1 zinc-RING finger domain UIM PF02809.20 RUS90421.1 - 0.01 15.7 0.2 0.029 14.3 0.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-C2H2 PF00096.26 RUS90421.1 - 0.029 14.8 0.8 0.029 14.8 0.8 7.2 9 1 0 9 9 9 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS90421.1 - 0.11 13.4 0.4 0.11 13.4 0.4 7.0 8 0 0 8 8 8 0 C2H2-type zinc finger zf-BED PF02892.15 RUS90421.1 - 0.14 12.2 3.7 0.77 9.8 0.0 3.0 3 0 0 3 3 3 0 BED zinc finger Prok-RING_4 PF14447.6 RUS90421.1 - 2.1 8.3 22.6 0.77 9.7 14.8 3.4 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS90421.1 - 3.4 8.1 24.4 0.065 13.6 14.5 2.8 2 0 0 2 2 2 0 Ring finger domain DUF4187 PF13821.6 RUS90421.1 - 4.1 7.3 13.5 0.29 11.0 2.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) Ald_Xan_dh_C2 PF02738.18 RUS90422.1 - 1.2e-61 208.8 0.0 5.8e-45 153.8 0.0 2.0 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 RUS90424.1 - 3.1e-30 104.0 0.3 9.6e-30 102.4 0.1 1.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 RUS90424.1 - 0.064 13.2 1.6 0.064 13.2 1.6 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain 7tm_1 PF00001.21 RUS90425.1 - 4.5e-56 190.1 17.1 6.1e-56 189.7 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS90425.1 - 2.6e-14 53.2 16.3 3.6e-14 52.8 16.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS90425.1 - 4.1e-13 49.6 15.9 6.5e-13 48.9 15.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS90425.1 - 6.5e-09 35.5 22.0 4.5e-07 29.5 22.0 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RUS90425.1 - 1.7e-08 34.1 14.6 2.5e-08 33.7 14.5 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srh PF10318.9 RUS90425.1 - 0.0026 16.9 19.7 0.0041 16.2 19.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Serpentine_r_xa PF03383.15 RUS90425.1 - 0.02 14.9 0.9 0.02 14.9 0.9 3.1 3 0 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa 7tm_4 PF13853.6 RUS90425.1 - 0.27 10.9 14.7 0.57 9.9 14.7 1.6 1 1 0 1 1 1 0 Olfactory receptor DUF1774 PF08611.10 RUS90425.1 - 5.9 7.3 12.9 1 9.7 1.8 3.4 1 1 3 4 4 4 0 Fungal protein of unknown function (DUF1774) EF-hand_6 PF13405.6 RUS90426.1 - 0.0004 20.1 3.5 0.012 15.4 0.2 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 RUS90426.1 - 0.00069 20.0 0.4 0.0042 17.5 0.4 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS90426.1 - 0.0037 17.1 0.0 0.02 14.7 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS90426.1 - 0.012 15.1 3.6 0.014 14.9 0.0 2.9 4 0 0 4 4 4 0 EF hand EF-hand_5 PF13202.6 RUS90426.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 EF hand START PF01852.19 RUS90428.1 - 1.4e-26 93.2 0.0 1.6e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 START domain Forkhead PF00250.18 RUS90429.1 - 8.3e-37 125.3 0.0 1.3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DAP3 PF10236.9 RUS90431.1 - 1.3e-63 215.1 0.0 1.6e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 RUS90431.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RBD-FIP PF09457.10 RUS90433.1 - 6.6e-09 35.5 1.5 6.6e-09 35.5 1.5 3.6 4 0 0 4 4 4 1 FIP domain EF-hand_7 PF13499.6 RUS90433.1 - 1.6e-05 25.3 1.4 9e-05 22.8 0.3 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS90433.1 - 3.1e-05 23.2 0.8 3.1e-05 23.2 0.8 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 RUS90433.1 - 0.00032 20.4 1.4 0.00032 20.4 1.4 3.1 3 0 0 3 3 3 1 EF-hand domain GP17 PF17420.2 RUS90433.1 - 0.53 10.5 0.0 0.53 10.5 0.0 2.6 3 0 0 3 3 3 0 Superinfection exclusion gene product 17 EF-hand_5 PF13202.6 RUS90433.1 - 0.69 9.5 4.8 0.24 11.0 0.3 2.7 4 0 0 4 4 4 0 EF hand Fib_alpha PF08702.10 RUS90433.1 - 1.3 9.2 14.7 6 7.1 3.7 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 RUS90433.1 - 3.7 6.8 15.8 1.8 7.9 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 RUS90433.1 - 8.5 7.1 33.6 2.2 9.0 7.9 3.9 2 2 1 3 3 3 0 Initiation control protein YabA I-set PF07679.16 RUS90434.1 - 3.2e-26 91.2 0.2 9.6e-09 35.2 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS90434.1 - 4.8e-25 88.0 8.8 2.8e-09 37.5 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 RUS90434.1 - 9.8e-15 54.7 6.3 1.3e-05 25.4 0.0 5.0 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 RUS90434.1 - 1.9e-08 34.4 11.2 3.7e-06 27.0 0.0 4.8 5 1 0 5 5 5 2 Immunoglobulin domain Rep_fac-A_3 PF08661.11 RUS90434.1 - 0.21 12.0 2.5 1.2 9.6 0.6 2.9 1 1 2 3 3 3 0 Replication factor A protein 3 HbrB PF08539.11 RUS90435.1 - 1.1e-07 32.0 1.3 1.1e-05 25.5 0.2 2.3 1 1 1 2 2 2 2 HbrB-like Reprolysin_2 PF13574.6 RUS90436.1 - 2.5e-27 96.1 0.2 4.3e-27 95.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RUS90436.1 - 1.7e-26 93.6 0.6 1.7e-26 93.6 0.6 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS90436.1 - 2.7e-16 60.2 0.1 6.5e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS90436.1 - 1.8e-11 44.1 0.0 3.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 RUS90436.1 - 2.9e-11 43.8 0.1 7e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.23 RUS90436.1 - 7.7e-10 39.4 28.8 7.7e-10 39.4 28.8 3.3 2 1 0 2 2 2 1 Disintegrin Reprolysin PF01421.19 RUS90436.1 - 0.001 19.0 0.0 0.0038 17.1 0.0 1.9 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.6 RUS90436.1 - 0.1 12.6 2.1 0.26 11.3 2.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF3810 PF12725.7 RUS90436.1 - 1.4 8.2 4.2 3.2 7.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) WD40 PF00400.32 RUS90437.1 - 1.2e-34 117.7 3.2 9.1e-10 39.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS90437.1 - 1.6e-08 34.8 0.0 0.2 11.9 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RUS90437.1 - 0.004 16.1 0.9 0.25 10.3 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 RUS90437.1 - 0.0055 15.6 0.1 0.82 8.5 0.0 2.8 2 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 RUS90437.1 - 0.022 13.4 0.7 0.069 11.8 0.1 2.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS90437.1 - 0.071 12.4 0.1 6.2 6.0 0.0 2.6 1 1 1 3 3 3 0 WD40-like domain Lipocalin_3 PF12702.7 RUS90437.1 - 0.076 13.1 0.2 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Lipocalin-like V-ATPase_G_2 PF16999.5 RUS90440.1 - 0.017 15.6 1.7 0.097 13.1 1.7 2.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TPR_1 PF00515.28 RUS90441.1 - 1.6e-35 119.5 9.9 2.8e-06 26.9 0.0 9.2 9 2 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS90441.1 - 2e-34 114.9 4.7 8.8e-06 25.5 0.0 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 RUS90441.1 - 1.5e-32 109.0 0.0 8.5e-06 25.6 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat DUF1736 PF08409.11 RUS90441.1 - 2.3e-30 104.4 1.9 5.4e-30 103.2 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_16 PF13432.6 RUS90441.1 - 7e-29 100.2 0.5 2.4e-06 28.1 0.0 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 RUS90441.1 - 2.4e-27 95.2 9.4 9.8e-06 26.0 0.1 6.6 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 RUS90441.1 - 4e-23 80.8 9.8 6.6e-08 32.1 0.1 7.6 5 2 4 9 9 8 4 TPR repeat TPR_17 PF13431.6 RUS90441.1 - 4.1e-22 76.9 13.2 0.00057 20.1 0.0 10.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 RUS90441.1 - 9.6e-20 70.7 8.9 0.00074 19.8 0.0 7.7 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 RUS90441.1 - 5.8e-19 67.2 9.6 0.21 12.5 0.0 10.0 2 2 8 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS90441.1 - 1.3e-14 53.1 1.8 0.0052 16.7 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 RUS90441.1 - 7.8e-14 51.3 1.0 0.7 10.7 0.0 8.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS90441.1 - 4.9e-12 45.8 3.5 0.16 12.2 0.1 5.5 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 RUS90441.1 - 6.3e-08 32.2 13.3 0.32 10.9 0.7 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RUS90441.1 - 3.1e-07 30.1 4.3 0.15 11.4 0.1 4.3 1 1 3 4 4 4 3 Coatomer epsilon subunit ANAPC3 PF12895.7 RUS90441.1 - 3.4e-06 27.2 3.8 1.7 8.9 0.0 4.8 2 2 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 PMT_2 PF13231.6 RUS90441.1 - 0.00013 22.2 7.0 0.00013 22.2 7.0 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_15 PF13429.6 RUS90441.1 - 0.00017 20.9 7.2 0.029 13.6 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS90441.1 - 0.0088 15.4 1.1 0.25 10.7 0.0 2.8 2 1 1 3 3 3 1 MalT-like TPR region HrpB1_HrpK PF09613.10 RUS90441.1 - 0.011 15.3 1.1 1.1 8.9 0.0 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 RUS90441.1 - 0.052 14.2 0.0 73 4.4 0.1 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat BTAD PF03704.17 RUS90441.1 - 0.057 13.9 0.6 1 9.8 0.1 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain NARP1 PF12569.8 RUS90441.1 - 0.15 11.0 14.8 1 8.2 0.4 4.4 2 1 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 RUS90441.1 - 0.56 9.9 11.5 0.74 9.5 0.8 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain Sel1 PF08238.12 RUS90441.1 - 7.1 7.5 5.6 47 4.9 0.1 5.1 8 0 0 8 8 5 0 Sel1 repeat ADH_zinc_N_2 PF13602.6 RUS90443.1 - 1.3e-20 74.8 0.0 2.9e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 RUS90443.1 - 6.3e-14 52.1 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS90443.1 - 5.5e-10 39.1 0.0 2.5e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlphaC_N PF08829.10 RUS90443.1 - 0.017 15.2 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha C protein N terminal 2-Hacid_dh_C PF02826.19 RUS90443.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 RUS90443.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Sugar_tr PF00083.24 RUS90445.1 - 1.2e-27 96.9 21.9 1.6e-27 96.5 21.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS90445.1 - 7.9e-25 87.5 53.4 2.1e-19 69.7 31.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2175 PF09943.9 RUS90447.1 - 0.045 14.0 0.1 8.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) ShK PF01549.24 RUS90447.1 - 9.8 6.8 17.3 1 9.9 10.4 3.0 3 0 0 3 3 3 0 ShK domain-like HLH PF00010.26 RUS90448.1 - 6.6e-12 45.2 0.3 1.5e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 RUS90448.1 - 0.0081 15.9 0.0 0.062 13.0 0.0 2.3 2 0 0 2 2 2 1 Transcription factor COE1 helix-loop-helix domain DivIC PF04977.15 RUS90448.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.25 RUS90449.1 - 6.4e-53 179.8 0.0 1.1e-52 179.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90449.1 - 2e-27 96.1 0.0 3.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS90449.1 - 1.7e-05 24.3 0.0 5.7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS90449.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS90449.1 - 0.029 13.2 0.3 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 RUS90449.1 - 0.03 13.9 0.1 0.075 12.6 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RUS90449.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Lamp PF01299.17 RUS90450.1 - 1.3e-15 57.5 10.6 2.3e-09 37.3 0.1 4.6 3 1 0 4 4 4 3 Lysosome-associated membrane glycoprotein (Lamp) Glyco_transf_7N PF13733.6 RUS90451.1 - 4.1e-54 181.8 0.0 7.2e-54 181.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS90451.1 - 4.9e-29 99.8 0.1 1.5e-28 98.2 0.3 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS90451.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 zf-CCHC PF00098.23 RUS90452.1 - 0.33 11.1 1.2 0.53 10.4 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn_ribbon_SprT PF17283.2 RUS90452.1 - 0.86 9.6 5.4 1.7 8.7 5.4 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 RUS90453.1 - 6.1e-37 123.1 89.2 0.00016 22.2 0.7 11.2 11 0 0 11 11 11 11 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS90453.1 - 1.5e-34 116.6 95.7 2.3e-05 24.6 0.8 11.2 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS90453.1 - 3.5e-24 84.5 72.7 0.013 15.8 1.5 11.3 11 0 0 11 11 11 11 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS90453.1 - 1.2e-22 79.5 80.8 0.0014 19.0 1.4 11.0 11 0 0 11 11 11 10 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RUS90453.1 - 2.2e-20 72.1 94.5 8e-07 29.2 1.3 12.0 13 0 0 13 13 13 8 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS90453.1 - 2.2e-11 43.5 93.1 6.7e-06 26.0 1.1 12.3 12 1 1 13 13 13 7 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS90453.1 - 0.00014 22.2 65.5 0.18 12.1 1.6 10.5 2 2 4 8 8 8 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 RUS90453.1 - 0.037 13.9 0.3 0.037 13.9 0.3 9.0 10 1 0 10 10 10 0 zinc-finger of a C2HC-type TRAF6_Z2 PF18048.1 RUS90453.1 - 0.31 11.2 0.1 0.31 11.2 0.1 5.6 7 0 0 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 PHD_4 PF16866.5 RUS90453.1 - 8.8 6.5 35.7 0.67 10.1 3.2 5.6 4 2 1 5 5 5 0 PHD-finger Ras PF00071.22 RUS90454.1 - 1.1e-55 187.7 0.3 1.2e-55 187.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS90454.1 - 1e-19 70.9 0.0 2.1e-19 69.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS90454.1 - 1.1e-09 37.9 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS90454.1 - 6.4e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS90454.1 - 7.2e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 RUS90454.1 - 0.00011 22.0 3.5 0.00037 20.3 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 RUS90454.1 - 0.03 14.2 0.1 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase RhoGAP PF00620.27 RUS90455.1 - 1.1e-16 61.0 0.5 1.1e-16 61.0 0.5 1.8 2 0 0 2 2 2 1 RhoGAP domain CLP1_N PF16573.5 RUS90456.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor RNase_Zc3h12a PF11977.8 RUS90457.1 - 2.3e-59 199.6 0.0 7e-59 198.1 0.0 1.9 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 RUS90457.1 - 2.8e-10 40.0 0.1 6.1e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Regnase_1_C PF18561.1 RUS90457.1 - 0.00012 21.7 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 RUS90457.1 - 0.00048 19.9 7.7 0.0012 18.6 7.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RUS90457.1 - 0.24 11.9 8.4 0.63 10.6 8.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 RUS90457.1 - 0.48 10.4 7.5 0.093 12.7 3.6 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) START PF01852.19 RUS90458.1 - 1.2e-17 64.0 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 RUS90458.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) Ferritin PF00210.24 RUS90459.1 - 3.5e-37 127.5 0.6 4.1e-37 127.3 0.6 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 RUS90459.1 - 0.00081 19.8 0.4 0.0011 19.3 0.4 1.4 1 1 0 1 1 1 1 Rubrerythrin IcmF_C PF06744.12 RUS90459.1 - 0.017 14.7 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal CUB PF00431.20 RUS90460.1 - 6.1e-52 174.6 5.7 1.8e-18 66.9 0.1 3.2 3 0 0 3 3 3 3 CUB domain VWC PF00093.18 RUS90461.1 - 2e-17 63.3 42.3 5.2e-11 42.7 20.8 6.1 4 1 2 6 6 4 2 von Willebrand factor type C domain EGF_3 PF12947.7 RUS90461.1 - 3.2e-13 49.6 45.3 4.6e-08 33.1 12.6 6.8 5 2 1 6 6 5 3 EGF domain EGF_CA PF07645.15 RUS90461.1 - 1.8e-08 34.4 28.4 2e-05 24.7 8.0 7.7 7 2 1 8 8 4 3 Calcium-binding EGF domain Laminin_G_3 PF13385.6 RUS90461.1 - 2e-06 28.1 0.0 1.1e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 RUS90461.1 - 3.1e-06 27.8 0.0 5.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain cEGF PF12662.7 RUS90461.1 - 4.4e-05 23.3 3.9 4.4e-05 23.3 3.9 6.9 7 1 1 8 8 7 4 Complement Clr-like EGF-like Laminin_G_1 PF00054.23 RUS90461.1 - 5.2e-05 23.5 0.0 9.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 RUS90461.1 - 0.0024 18.1 21.1 0.0064 16.8 8.8 7.7 6 1 0 6 6 4 4 EGF-like domain EGF_MSP1_1 PF12946.7 RUS90461.1 - 0.012 15.6 6.4 0.012 15.6 6.4 6.1 7 0 0 7 7 5 0 MSP1 EGF domain 1 CFC PF09443.10 RUS90461.1 - 0.017 15.0 2.7 0.017 15.0 2.7 4.2 4 0 0 4 4 3 0 Cripto_Frl-1_Cryptic (CFC) EGF_2 PF07974.13 RUS90461.1 - 0.018 15.4 11.9 0.018 15.4 11.9 8.8 5 2 3 8 8 5 0 EGF-like domain hEGF PF12661.7 RUS90461.1 - 0.049 14.3 2.0 0.049 14.3 2.0 9.0 11 0 0 11 11 7 0 Human growth factor-like EGF CENP-F_leu_zip PF10473.9 RUS90461.1 - 0.27 11.3 0.7 0.43 10.6 0.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rad50_zn_hook PF04423.14 RUS90461.1 - 5.2 7.0 17.2 2.5 8.0 0.8 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Bac_export_3 PF01313.19 RUS90462.1 - 6.7 6.7 9.6 0.42 10.6 2.3 2.2 2 0 0 2 2 2 0 Bacterial export proteins, family 3 DEAD PF00270.29 RUS90463.1 - 2e-49 167.7 0.8 8e-49 165.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS90463.1 - 1.7e-24 86.3 0.0 3.2e-23 82.2 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RUS90463.1 - 9.4e-19 67.4 0.6 2.2e-18 66.2 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_30 PF13604.6 RUS90463.1 - 0.042 13.6 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RUS90463.1 - 0.056 13.7 0.5 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain CENP-B_dimeris PF09026.10 RUS90463.1 - 0.17 12.3 5.3 0.35 11.3 5.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SKA1 PF07160.12 RUS90463.1 - 3 7.6 10.9 0.44 10.3 5.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pkinase PF00069.25 RUS90464.1 - 7.6e-76 254.9 0.0 5.2e-72 242.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90464.1 - 5.1e-33 114.4 0.0 1.1e-32 113.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 RUS90464.1 - 8.5e-07 29.6 2.3 2.7e-06 28.0 2.0 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 RUS90464.1 - 2.8e-06 26.8 0.0 5.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS90464.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 RUS90464.1 - 0.00073 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 RUS90464.1 - 0.013 14.4 0.0 0.031 13.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 RUS90464.1 - 0.03 14.2 0.0 0.32 10.9 0.0 2.5 1 1 2 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_1f PF01921.18 RUS90464.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) RIO1 PF01163.22 RUS90464.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PcfK PF14058.6 RUS90465.1 - 0.0025 18.1 0.5 0.042 14.1 0.2 2.5 2 0 0 2 2 2 1 PcfK-like protein DNA_ligase_OB_2 PF14743.6 RUS90466.1 - 1.8e-26 91.9 0.9 3.7e-26 90.9 0.3 1.9 2 0 0 2 2 2 1 DNA ligase OB-like domain zf-CCHH PF10283.9 RUS90466.1 - 1.9e-16 59.7 20.2 3.3e-08 33.4 7.8 2.7 2 0 0 2 2 2 2 PBZ domain DNA_ligase_A_M PF01068.21 RUS90466.1 - 6.4e-13 48.8 0.0 2.1e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 RUS90466.1 - 8e-07 29.5 0.5 5.9e-06 26.7 0.5 2.2 1 1 0 1 1 1 1 RNA ligase Brr6_like_C_C PF10104.9 RUS90466.1 - 1.2 9.0 4.5 16 5.2 0.3 2.4 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain R3H-assoc PF13902.6 RUS90466.1 - 2.9 8.3 6.0 1.1 9.7 1.3 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain Tsg PF04668.12 RUS90467.1 - 1.1e-43 149.1 4.7 1.1e-43 149.1 4.7 2.4 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region MG2 PF01835.19 RUS90468.1 - 1.9e-08 34.6 0.4 1.9e-07 31.5 0.0 2.7 3 0 0 3 3 3 1 MG2 domain MG3 PF17791.1 RUS90468.1 - 5.2e-07 29.9 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 RUS90468.1 - 0.078 13.1 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 Macroglobulin domain MG4 Alg6_Alg8 PF03155.15 RUS90469.1 - 1.3e-133 446.5 22.6 1.5e-133 446.3 22.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF5381 PF17353.2 RUS90469.1 - 0.71 9.6 0.0 0.71 9.6 0.0 2.8 3 1 1 4 4 4 0 Family of unknown function (DUF5381) DUF3365 PF11845.8 RUS90471.1 - 0.0099 16.2 0.9 0.027 14.8 1.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3365) EVC2_like PF12297.8 RUS90472.1 - 1.6e-66 224.8 18.6 1.6e-66 224.8 18.6 4.0 2 1 2 4 4 4 1 Ellis van Creveld protein 2 like protein OATP PF03137.20 RUS90473.1 - 1.3 7.2 2.2 0.85 7.8 0.0 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HisKA_3 PF07730.13 RUS90474.1 - 0.01 16.3 2.9 0.082 13.4 0.1 3.0 2 1 0 2 2 2 0 Histidine kinase ARGLU PF15346.6 RUS90474.1 - 1.1 9.1 19.9 19 5.1 18.6 2.2 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 SPG4 PF17325.2 RUS90474.1 - 1.4 10.0 7.9 0.17 13.0 1.0 2.4 1 1 1 2 2 2 0 Stationary phase protein 4 PVL_ORF50 PF07768.11 RUS90474.1 - 7.2 7.0 8.4 2.5 8.5 4.9 2.0 1 1 1 2 2 2 0 PVL ORF-50-like family Ribosomal_L27e PF01777.18 RUS90475.1 - 4.4e-36 123.1 12.5 5.5e-36 122.8 12.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 RUS90475.1 - 1.5e-06 27.9 0.4 3.9e-06 26.6 0.4 1.7 1 0 0 1 1 1 1 KOW motif Kelch_1 PF01344.25 RUS90476.1 - 3.3e-23 81.0 19.1 1.9e-06 27.4 0.1 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 RUS90476.1 - 2.6e-16 59.3 9.6 2.5e-07 30.6 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RUS90476.1 - 8e-16 57.7 21.0 7.6e-06 26.0 0.1 6.8 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 RUS90476.1 - 9.9e-16 57.0 14.3 1.4e-05 24.9 0.1 6.3 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 RUS90476.1 - 5.9e-14 51.7 14.1 0.00068 19.6 0.2 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 RUS90476.1 - 1.2e-13 50.9 10.5 0.00092 19.4 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain PSI PF01437.25 RUS90476.1 - 0.00041 20.8 42.8 0.002 18.6 19.4 9.1 6 2 2 8 8 8 3 Plexin repeat Laminin_EGF PF00053.24 RUS90476.1 - 0.00044 20.3 17.7 0.00044 20.3 17.7 9.0 7 2 1 8 8 8 3 Laminin EGF domain EGF_2 PF07974.13 RUS90476.1 - 0.0077 16.6 11.1 0.0077 16.6 11.1 9.4 9 2 1 10 10 10 3 EGF-like domain DUF4773 PF15998.5 RUS90477.1 - 1.7e-19 70.4 5.2 3.1e-19 69.6 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) ATP-synt_ab PF00006.25 RUS90478.1 - 2.9e-73 246.0 0.0 4.1e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RUS90478.1 - 5e-46 156.1 1.2 8.6e-46 155.4 1.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RUS90478.1 - 8e-19 67.9 1.6 1.6e-18 66.9 0.9 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 RUS90478.1 - 0.044 13.1 0.0 0.094 12.0 0.0 1.6 1 0 0 1 1 1 0 KaiC HAS-barrel PF09378.10 RUS90478.1 - 0.051 13.7 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 HAS barrel domain GDA1_CD39 PF01150.17 RUS90479.1 - 3.3e-117 391.7 0.0 4.1e-117 391.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BatA PF07584.11 RUS90479.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Smim3 PF17307.2 RUS90479.1 - 0.2 11.2 0.6 0.44 10.1 0.6 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 Sec20 PF03908.13 RUS90480.1 - 1.7e-23 82.4 1.1 1.7e-23 82.4 1.1 2.0 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 RUS90480.1 - 0.017 14.5 4.4 0.023 14.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 RUS90480.1 - 0.022 14.6 10.5 0.032 14.1 10.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain AI-2E_transport PF01594.16 RUS90480.1 - 0.12 11.5 1.8 0.19 10.9 0.5 1.8 2 0 0 2 2 2 0 AI-2E family transporter DUF4820 PF16091.5 RUS90480.1 - 0.12 11.7 7.9 0.16 11.3 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Synaptobrevin PF00957.21 RUS90480.1 - 0.3 10.9 2.8 0.32 10.8 0.6 2.3 1 1 1 2 2 2 0 Synaptobrevin Exonuc_VII_L PF02601.15 RUS90480.1 - 0.35 10.4 8.2 0.47 10.0 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-18_N PF10496.9 RUS90480.1 - 0.39 11.0 4.9 0.57 10.5 4.0 1.8 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ALMT PF11744.8 RUS90480.1 - 0.41 9.4 6.7 0.49 9.2 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF349 PF03993.12 RUS90480.1 - 0.43 10.9 6.1 0.78 10.1 4.2 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) YkuI_C PF10388.9 RUS90480.1 - 0.83 9.4 5.0 2.9 7.7 0.0 2.5 2 1 0 2 2 2 0 EAL-domain associated signalling protein domain YabA PF06156.13 RUS90480.1 - 2.5 8.8 12.0 0.61 10.7 6.5 2.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF883 PF05957.13 RUS90480.1 - 3.1 8.5 8.3 25 5.5 1.8 3.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) ING PF12998.7 RUS90480.1 - 3.3 8.4 9.0 3.3 8.4 4.5 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 RUS90480.1 - 6.2 6.9 12.5 3.5 7.7 1.7 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 RUS90480.1 - 7.1 7.3 11.2 8 7.1 5.6 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF16 PF01519.16 RUS90480.1 - 7.8 7.0 10.2 8.7 6.9 7.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 RNase_H PF00075.24 RUS90481.1 - 1.4e-15 57.7 0.0 1.6e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 RNase H Trypsin_2 PF13365.6 RUS90482.1 - 1.6e-30 107.0 0.5 2.9e-30 106.2 0.5 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 RUS90482.1 - 2e-14 54.0 0.0 3.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 RUS90482.1 - 5e-11 42.3 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS90482.1 - 1.5e-10 41.2 0.1 3.4e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 RUS90482.1 - 6.2e-07 29.7 0.5 1.7e-06 28.3 0.2 2.0 2 0 0 2 2 2 1 PDZ domain LSM PF01423.22 RUS90482.1 - 0.0056 16.3 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 LSM domain Peptidase_S46 PF10459.9 RUS90482.1 - 0.017 13.8 1.4 1.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 HAS-barrel PF09378.10 RUS90482.1 - 0.017 15.2 0.1 1.3 9.2 0.0 3.1 2 1 1 3 3 3 0 HAS barrel domain Ig_3 PF13927.6 RUS90485.1 - 1.5e-35 121.6 1.5 2e-13 50.8 0.7 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 RUS90485.1 - 8.8e-33 112.2 0.1 1.4e-09 37.9 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 RUS90485.1 - 8.6e-25 86.7 0.1 3.8e-08 33.4 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 RUS90485.1 - 7e-24 84.0 0.2 1.6e-08 34.7 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 RUS90485.1 - 8.4e-16 58.1 3.8 2.5e-06 27.6 0.0 4.9 4 1 1 5 5 5 3 Immunoglobulin V-set domain CUB PF00431.20 RUS90485.1 - 2.1e-13 50.5 0.0 7.4e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 CUB domain Ig_4 PF16680.5 RUS90485.1 - 3.2e-06 27.3 1.7 4 7.8 0.0 4.8 3 2 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 RUS90485.1 - 9e-06 25.2 0.1 0.02 14.5 0.0 3.2 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS90485.1 - 0.00035 20.6 0.0 2.3 8.3 0.0 3.5 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 RUS90485.1 - 0.00096 19.2 0.2 0.36 10.9 0.0 3.9 3 1 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 RUS90485.1 - 0.0037 17.6 0.5 1.5 9.3 0.3 3.4 4 1 0 4 4 3 1 Immunoglobulin C1-set domain IBR PF01485.21 RUS90486.1 - 1.2e-22 79.9 45.0 8.5e-16 57.9 9.2 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 RUS90486.1 - 0.00016 21.5 2.7 0.00016 21.5 2.7 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS90486.1 - 0.0009 19.1 2.8 0.0009 19.1 2.8 5.2 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS90486.1 - 0.003 17.5 1.7 0.003 17.5 1.7 5.1 5 0 0 5 5 5 2 RING-type zinc-finger zf-RING_2 PF13639.6 RUS90486.1 - 0.0055 17.0 3.1 0.0055 17.0 3.1 5.1 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 RUS90486.1 - 0.26 11.5 30.7 0.1 12.8 2.9 5.0 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-H2C2_5 PF13909.6 RUS90487.1 - 2.9e-12 46.1 38.1 0.00044 20.0 0.1 8.0 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RUS90487.1 - 1.1e-08 35.2 60.6 0.16 12.9 0.4 10.3 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS90487.1 - 3.1e-08 33.6 51.4 0.2 12.2 0.3 9.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS90487.1 - 4.4e-07 30.0 73.9 0.013 15.9 1.7 10.3 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_2 PF12756.7 RUS90487.1 - 0.021 15.2 54.2 0.97 9.8 3.7 6.7 2 2 5 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 RUS90487.1 - 0.65 9.9 6.7 6.8 6.6 0.1 4.1 3 0 0 3 3 3 0 Zinc knuckle RR_TM4-6 PF06459.12 RUS90488.1 - 7.1 6.4 10.6 8.3 6.1 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0556 PF10572.9 RUS90489.1 - 4.8e-07 29.4 0.0 7.5e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0556 SAPIS-gp6 PF16722.5 RUS90489.1 - 0.052 13.9 0.1 0.079 13.4 0.1 1.3 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus tRNA-synt_1e PF01406.19 RUS90489.1 - 0.053 12.9 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PINIT PF14324.6 RUS90490.1 - 1.9e-36 125.6 0.1 3.9e-36 124.6 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 RUS90490.1 - 8.1e-22 76.7 5.9 1.4e-21 75.9 5.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 RUS90490.1 - 1.4e-05 24.8 2.1 2.6e-05 23.9 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SRF-TF PF00319.18 RUS90492.1 - 1.2e-23 82.3 0.3 1.7e-23 81.8 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 RUS90492.1 - 0.2 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Nop14 PF04147.12 RUS90493.1 - 0.00028 19.3 19.7 0.00028 19.3 19.7 2.0 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 RUS90493.1 - 0.0014 18.2 59.4 0.014 14.9 24.1 2.3 2 0 0 2 2 2 2 SDA1 CDC45 PF02724.14 RUS90493.1 - 0.14 10.4 56.2 0.046 12.0 21.5 2.1 2 0 0 2 2 2 0 CDC45-like protein CobT PF06213.12 RUS90493.1 - 0.35 10.2 46.3 0.14 11.5 17.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.10 RUS90493.1 - 4.8 7.5 21.6 0.26 11.6 3.5 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 RUS90493.1 - 9.7 4.5 56.2 2.7 6.3 20.5 2.1 2 0 0 2 2 2 0 Mpp10 protein SRF-TF PF00319.18 RUS90494.1 - 8.9e-25 85.9 0.4 1.4e-24 85.3 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 RUS90494.1 - 0.01 15.9 0.2 0.01 15.9 0.2 2.4 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF4116 PF13475.6 RUS90494.1 - 0.085 12.6 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) GHD PF17834.1 RUS90494.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase RVT_1 PF00078.27 RUS90495.1 - 2e-48 164.8 0.3 2e-48 164.8 0.3 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.29 RUS90496.1 - 6.4e-52 175.9 0.0 1.9e-51 174.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS90496.1 - 2.3e-30 105.2 0.0 2.9e-29 101.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 RUS90496.1 - 0.052 13.9 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain BBL5 PF07289.11 RUS90497.1 - 2.3e-151 503.5 0.0 2.6e-151 503.3 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 RUS90497.1 - 1.9e-05 24.7 0.0 0.026 14.7 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 RUS90497.1 - 8.9e-05 22.4 0.1 0.13 12.2 0.0 2.9 2 1 1 3 3 3 2 GRAM domain Voldacs PF03517.13 RUS90497.1 - 0.00077 19.6 0.1 0.57 10.3 0.0 3.0 2 1 0 2 2 2 2 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 RUS90497.1 - 0.053 13.9 0.0 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain bPH_3 PF14470.6 RUS90497.1 - 0.065 13.6 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain Synapsin_C PF02750.14 RUS90498.1 - 0.023 14.2 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Synapsin, ATP binding domain DUF3188 PF11384.8 RUS90498.1 - 0.22 11.3 0.1 0.36 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) H_lectin PF09458.10 RUS90499.1 - 7.9e-17 61.2 0.3 1.2e-15 57.4 0.0 2.5 3 0 0 3 3 3 1 H-type lectin domain BLOC1_2 PF10046.9 RUS90499.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 H_lectin PF09458.10 RUS90500.1 - 3.1e-14 52.9 0.0 5.6e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 H-type lectin domain APG6_N PF17675.1 RUS90500.1 - 0.01 16.4 1.0 0.018 15.6 1.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region PCB_OB PF17092.5 RUS90500.1 - 0.14 12.9 0.1 0.53 11.1 0.0 1.9 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain Homeodomain PF00046.29 RUS90501.1 - 2.1e-19 69.1 6.7 2.1e-19 69.1 6.7 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 RUS90501.1 - 0.016 15.1 0.2 0.035 14.0 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 RUS90501.1 - 0.026 14.0 0.2 0.056 12.9 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez E1-E2_ATPase PF00122.20 RUS90502.1 - 4.9 6.6 9.3 3.7 7.0 0.2 3.0 2 1 1 3 3 3 0 E1-E2 ATPase UPF0182 PF03699.13 RUS90502.1 - 5.7 4.9 5.3 0.39 8.8 0.5 1.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) EGF_CA PF07645.15 RUS90503.1 - 0 1047.1 742.9 2.8e-11 43.4 8.2 48.6 48 1 1 49 49 49 44 Calcium-binding EGF domain cEGF PF12662.7 RUS90503.1 - 1.3e-239 773.2 428.0 3.1e-09 36.6 3.8 50.2 48 0 0 48 48 48 45 Complement Clr-like EGF-like EGF PF00008.27 RUS90503.1 - 2e-104 341.3 680.4 4.2e-05 23.8 6.4 50.3 48 0 0 48 48 48 42 EGF-like domain FXa_inhibition PF14670.6 RUS90503.1 - 5.4e-96 314.6 725.2 1.3e-10 41.3 9.4 49.6 45 3 3 48 48 48 40 Coagulation Factor Xa inhibitory site TB PF00683.17 RUS90503.1 - 2.1e-95 312.2 147.7 3.6e-13 49.0 7.8 11.3 9 0 0 9 9 9 9 TB domain hEGF PF12661.7 RUS90503.1 - 1.3e-84 276.2 679.4 0.0007 20.1 6.2 52.8 52 0 0 52 52 52 44 Human growth factor-like EGF EGF_3 PF12947.7 RUS90503.1 - 2.3e-53 178.1 607.0 1.1e-10 41.5 10.3 49.0 46 2 2 48 48 48 39 EGF domain Fibrillin_U_N PF18193.1 RUS90503.1 - 1.7e-11 44.0 4.3 1.7e-11 44.0 4.3 8.7 8 0 0 8 8 8 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 RUS90503.1 - 8e-08 32.5 508.0 0.003 17.8 5.3 46.2 42 4 3 45 45 45 25 Pvs28 EGF domain Hamartin PF04388.12 RUS90504.1 - 1.4 7.5 5.8 1.6 7.3 5.8 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4106 PF13388.6 RUS90504.1 - 1.7 7.8 3.3 1.9 7.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) VWA_2 PF13519.6 RUS90505.1 - 2.4e-17 63.5 0.0 1.6e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Arrestin_N PF00339.29 RUS90506.1 - 1.1e-14 54.7 1.2 1.6e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS90506.1 - 2.2e-05 24.9 0.1 0.073 13.5 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Presenilin PF01080.17 RUS90506.1 - 2.5 6.8 7.6 4.2 6.0 7.6 1.4 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 RUS90506.1 - 5.6 6.5 22.0 11 5.5 22.0 1.5 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 RUS90506.1 - 8.9 6.2 13.4 15 5.4 13.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PTN_MK_N PF05196.13 RUS90507.1 - 0.07 13.4 0.1 0.34 11.2 0.1 2.2 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain CDC45 PF02724.14 RUS90509.1 - 0.0036 15.7 3.3 0.0038 15.6 3.3 1.0 1 0 0 1 1 1 1 CDC45-like protein HR1 PF02185.16 RUS90509.1 - 0.045 13.9 1.8 0.07 13.3 1.8 1.3 1 0 0 1 1 1 0 Hr1 repeat DUF4611 PF15387.6 RUS90509.1 - 0.055 13.7 4.4 0.1 12.8 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.11 RUS90509.1 - 0.21 9.7 25.4 0.022 12.9 20.6 1.5 1 1 1 2 2 2 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 RUS90509.1 - 0.63 10.0 5.3 0.97 9.4 5.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal eIF-3c_N PF05470.12 RUS90509.1 - 0.69 8.1 3.7 0.79 8.0 3.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus WRNPLPNID PF15017.6 RUS90509.1 - 1.1 10.2 6.2 2 9.3 6.2 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box FAM176 PF14851.6 RUS90509.1 - 2.1 8.0 5.9 2.9 7.5 5.9 1.2 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 RUS90509.1 - 2.1 8.8 10.0 3.8 8.0 10.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.12 RUS90509.1 - 5.2 5.6 19.3 0.58 8.7 14.9 1.6 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 RUS90509.1 - 7.6 4.5 7.0 8.9 4.3 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Lectin_C PF00059.21 RUS90510.1 - 7.6e-06 26.6 0.0 8.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain Reprolysin_5 PF13688.6 RUS90511.1 - 3.4e-19 69.8 0.1 1.1e-18 68.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS90511.1 - 4.1e-14 53.2 0.0 7.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS90511.1 - 2e-12 47.4 0.1 1e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS90511.1 - 2.7e-12 46.8 0.0 9.8e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 RUS90511.1 - 1e-10 41.9 5.5 1e-10 41.9 5.5 4.0 3 1 1 5 5 5 1 ADAM cysteine-rich domain Reprolysin PF01421.19 RUS90511.1 - 4.8e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Metallopep PF12044.8 RUS90511.1 - 0.00039 19.1 0.5 0.00062 18.5 0.5 1.2 1 0 0 1 1 1 1 Putative peptidase family PLAC PF08686.11 RUS90511.1 - 0.0069 17.1 53.4 0.1 13.4 3.2 6.0 5 0 0 5 5 5 3 PLAC (protease and lacunin) domain Peptidase_M66 PF10462.9 RUS90511.1 - 0.038 12.9 0.3 0.064 12.2 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Ribosomal_S25 PF03297.15 RUS90512.1 - 2e-45 153.1 4.6 2.5e-45 152.8 4.6 1.2 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 RUS90512.1 - 0.00021 21.4 0.1 0.0004 20.5 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 RUS90512.1 - 0.013 15.4 0.4 0.026 14.4 0.2 1.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 RUS90512.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 MarR family CdiA_C_tRNase PF18664.1 RUS90513.1 - 2.1e-05 24.7 11.5 0.67 10.2 0.3 4.1 1 1 4 5 5 5 5 CdiA C-terminal tRNase domain PSII_BNR PF14870.6 RUS90513.1 - 0.0053 16.1 5.4 0.81 8.9 0.1 2.9 1 1 2 3 3 3 3 Photosynthesis system II assembly factor YCF48 Ribosomal_L9_N PF01281.19 RUS90513.1 - 0.022 14.3 14.3 21 4.8 0.1 6.0 1 1 5 6 6 6 0 Ribosomal protein L9, N-terminal domain DUF3833 PF12915.7 RUS90513.1 - 0.45 10.1 7.7 4.8 6.7 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3833) KOW PF00467.29 RUS90513.1 - 0.93 9.5 9.2 2.1e+02 2.1 0.0 5.7 3 1 4 7 7 7 0 KOW motif Tetraspanin PF00335.20 RUS90514.1 - 0.0001 22.1 0.1 0.00012 21.9 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Usp PF00582.26 RUS90515.1 - 4.2e-22 79.2 0.3 8.8e-15 55.5 0.1 2.1 2 0 0 2 2 2 2 Universal stress protein family zf-BED PF02892.15 RUS90516.1 - 4.1e-09 36.3 1.7 8.1e-09 35.4 1.7 1.5 1 0 0 1 1 1 1 BED zinc finger FAD_binding_1 PF00667.20 RUS90516.1 - 0.075 12.6 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Dimer_Tnp_hAT PF05699.14 RUS90517.1 - 2.8e-13 49.4 0.0 1.2e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 RUS90517.1 - 0.0043 17.4 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) UPF0058 PF01893.16 RUS90518.1 - 5e-05 23.5 1.2 67 3.9 0.0 6.7 1 1 7 8 8 8 0 Uncharacterised protein family UPF0058 Put_DNA-bind_N PF06971.13 RUS90518.1 - 0.0005 20.0 0.0 19 5.4 0.0 4.4 1 1 5 6 6 6 2 Putative DNA-binding protein N-terminus Organ_specific PF10950.8 RUS90518.1 - 0.0019 18.9 0.2 2.1 9.1 0.1 2.3 1 1 1 2 2 2 2 Organ specific protein DUF3208 PF11482.8 RUS90518.1 - 0.011 16.1 2.1 1.2 9.5 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3208) NTS_2 PF15448.6 RUS90518.1 - 0.013 15.9 7.5 1.3e+02 3.0 0.1 6.7 1 1 7 8 8 8 0 N-terminal segments of P. falciparum erythrocyte membrane protein DUF2691 PF10903.8 RUS90518.1 - 0.059 13.3 0.1 20 5.1 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2691) Drf_FH1 PF06346.12 RUS90519.1 - 0.0075 16.0 0.4 0.011 15.5 0.4 1.3 1 0 0 1 1 1 1 Formin Homology Region 1 IFT43 PF15305.6 RUS90519.1 - 0.091 12.9 1.3 20 5.4 0.3 3.5 1 1 2 3 3 3 0 Intraflagellar transport protein 43 THB PF18362.1 RUS90519.1 - 2.2 8.0 4.2 1.9e+02 1.8 0.1 3.7 4 0 0 4 4 4 0 Tri-helix bundle domain GATase_7 PF13537.6 RUS90520.1 - 0.0033 17.3 2.1 8.1 6.4 0.1 3.7 1 1 2 4 4 4 2 Glutamine amidotransferase domain DUF1030 PF06270.11 RUS90520.1 - 0.11 12.2 0.9 23 4.8 0.0 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1030) Glyco_hydro_19 PF00182.19 RUS90520.1 - 0.28 11.0 2.0 38 4.1 0.1 3.5 1 1 3 4 4 4 0 Chitinase class I NtA PF03146.15 RUS90520.1 - 0.3 11.0 1.1 12 5.8 0.3 2.9 1 1 1 2 2 2 0 Agrin NtA domain DUF1856 PF08983.10 RUS90521.1 - 0.00023 21.3 51.9 0.036 14.3 8.2 6.8 2 1 3 5 5 5 5 Domain of unknown function (DUF1856) Mucin-like PF16058.5 RUS90523.1 - 1e-11 44.8 0.0 0.0032 17.5 0.0 3.0 1 1 2 3 3 3 3 Mucin-like DUF3672 PF12421.8 RUS90523.1 - 2.4e-09 37.2 36.3 0.14 12.0 2.4 5.6 1 1 4 5 5 5 5 Fibronectin type III protein WG_beta_rep PF14903.6 RUS90525.1 - 0.0073 16.6 7.5 3.4e+02 1.7 0.0 7.2 8 0 0 8 8 8 0 WG containing repeat Crisp PF08562.10 RUS90526.1 - 0.0059 17.2 43.3 8.4 7.1 3.8 6.6 1 1 5 6 6 6 5 Crisp Crisp PF08562.10 RUS90527.1 - 0.0052 17.4 80.3 0.23 12.1 8.1 7.0 1 1 6 7 7 7 6 Crisp PAP_assoc PF03828.19 RUS90528.1 - 1.2e-13 51.1 0.1 2.8e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RUS90528.1 - 6.3e-05 23.2 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SWIB PF02201.18 RUS90528.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain Polbeta PF18765.1 RUS90528.1 - 0.099 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase RPE65 PF03055.15 RUS90529.1 - 1.2e-96 324.7 0.0 1.5e-96 324.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ldh_2 PF02615.14 RUS90530.1 - 2.5e-17 63.0 0.0 2.9e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ADH_zinc_N PF00107.26 RUS90531.1 - 2.8e-26 92.0 0.1 4.5e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS90531.1 - 5.9e-06 27.4 0.0 8.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS90531.1 - 0.005 16.7 1.2 0.011 15.6 1.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 RUS90531.1 - 0.052 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 RUS90531.1 - 0.09 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS90531.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_C2 PF00648.21 RUS90532.1 - 9.7e-101 336.7 0.0 1.4e-100 336.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RUS90532.1 - 2.6e-29 102.3 0.0 5.2e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 RUS90532.1 - 8.2e-08 31.6 1.1 0.0047 16.8 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RUS90532.1 - 7.6e-07 28.9 0.7 5.8e-05 22.9 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 RUS90532.1 - 2.4e-06 27.9 0.6 0.074 13.5 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS90532.1 - 5.3e-05 22.5 0.2 1.8 8.3 0.0 3.8 3 0 0 3 3 3 2 EF hand RVT_2 PF07727.14 RUS90533.1 - 6.8e-48 163.4 0.0 1.5e-47 162.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 RUS90533.1 - 4.3e-19 68.9 0.7 2.5e-18 66.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 RUS90533.1 - 2.9e-06 27.0 1.8 2.9e-06 27.0 1.8 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain NAD_binding_4 PF07993.12 RUS90533.1 - 0.045 12.9 0.3 0.1 11.8 0.2 1.6 2 0 0 2 2 2 0 Male sterility protein rve_3 PF13683.6 RUS90533.1 - 0.087 12.6 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UvrB PF12344.8 RUS90535.1 - 0.077 12.9 0.7 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 Ultra-violet resistance protein B Glyco_transf_10 PF00852.19 RUS90537.1 - 2e-30 105.8 0.1 2.3e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF4451 PF14616.6 RUS90537.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) DHHC PF01529.20 RUS90540.1 - 3.1e-31 108.2 10.1 3.1e-31 108.2 10.1 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase SH3_2 PF07653.17 RUS90540.1 - 0.0029 17.2 0.5 0.0076 15.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 RUS90540.1 - 0.018 14.9 0.1 0.056 13.3 0.1 1.8 1 1 0 1 1 1 0 Variant SH3 domain ANAPC16 PF17256.2 RUS90541.1 - 3e-05 24.3 0.2 4.6e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 16 Gon7 PF08738.10 RUS90541.1 - 0.011 15.8 0.3 0.012 15.6 0.3 1.1 1 0 0 1 1 1 0 Gon7 family Spb1_C PF07780.12 RUS90542.1 - 0.75 9.4 4.7 0.09 12.4 0.4 1.6 2 0 0 2 2 2 0 Spb1 C-terminal domain 7tm_1 PF00001.21 RUS90543.1 - 8.6e-09 35.1 4.1 1.5e-08 34.3 4.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SPRY PF00622.28 RUS90544.1 - 2.1e-20 73.0 1.7 2.7e-19 69.4 1.7 2.4 1 1 0 1 1 1 1 SPRY domain SAPS PF04499.15 RUS90545.1 - 1.6 7.4 4.8 2.5 6.8 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Myb_DNA-binding PF00249.31 RUS90546.1 - 7.6e-09 35.6 0.1 2.1e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RUS90546.1 - 0.00052 20.2 0.2 0.0013 19.0 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WSK PF03832.13 RUS90546.1 - 0.073 12.8 1.5 0.51 10.1 0.0 2.8 2 0 0 2 2 2 0 WSK motif Gelsolin PF00626.22 RUS90547.1 - 6.5e-59 195.8 0.0 1.4e-16 60.2 0.0 5.5 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 RUS90547.1 - 1.8e-14 53.5 5.6 6.5e-14 51.7 5.6 2.1 1 0 0 1 1 1 1 Villin headpiece domain CutA1 PF03091.15 RUS90547.1 - 0.11 12.4 0.8 7.1 6.6 0.1 2.7 3 0 0 3 3 3 0 CutA1 divalent ion tolerance protein Gelsolin PF00626.22 RUS90548.1 - 1.2e-13 50.7 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Gelsolin repeat SOGA PF11365.8 RUS90550.1 - 0.04 15.1 0.9 0.065 14.4 0.6 1.6 1 1 0 1 1 1 0 Protein SOGA CAP_GLY PF01302.25 RUS90551.1 - 6.3e-17 61.4 0.1 1e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DOCK_N PF16172.5 RUS90552.1 - 0.01 14.8 3.3 0.015 14.2 3.3 1.4 1 0 0 1 1 1 0 DOCK N-terminus DUF3037 PF11236.8 RUS90553.1 - 0.013 15.9 11.8 16 5.9 0.8 4.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) Vint PF14623.6 RUS90553.1 - 3 7.6 16.1 2.4e+02 1.4 0.3 3.4 1 1 1 2 2 2 0 Hint-domain RNase_H PF00075.24 RUS90555.1 - 1.6e-06 28.3 0.1 2.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 RNase H Pro_isomerase PF00160.21 RUS90556.1 - 2.4e-47 161.1 0.5 4.5e-47 160.2 0.5 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RUS90556.1 - 3.7e-19 68.3 0.0 8.4e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RUS90556.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS90556.1 - 0.057 13.4 0.2 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RUS90556.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Sel1 PF08238.12 RUS90557.1 - 3.8e-19 68.7 0.6 2.3e-07 31.2 0.0 4.6 5 0 0 5 5 5 4 Sel1 repeat Tctex-1 PF03645.13 RUS90559.1 - 1.1e-23 83.5 0.2 1.4e-23 83.1 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family SGL PF08450.12 RUS90560.1 - 1.9e-80 270.0 0.5 2.2e-80 269.8 0.5 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 RUS90560.1 - 8.7e-05 22.3 0.5 0.26 11.6 0.1 2.9 2 0 0 2 2 2 2 Two component regulator propeller NHL PF01436.21 RUS90560.1 - 0.00032 20.6 0.0 0.0009 19.2 0.0 1.8 1 0 0 1 1 1 1 NHL repeat DUF839 PF05787.13 RUS90560.1 - 0.02 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) zf-H2C2_5 PF13909.6 RUS90561.1 - 0.081 12.7 0.1 0.081 12.7 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain DUF3447 PF11929.8 RUS90561.1 - 0.11 12.4 0.1 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) zf_C2H2_ZHX PF18387.1 RUS90561.1 - 0.21 11.2 25.5 0.53 10.0 0.0 5.1 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Sec23_Sec24 PF04810.15 RUS90561.1 - 0.41 10.8 2.3 20 5.3 0.1 3.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 RUS90561.1 - 7.6 6.9 19.9 2.5 8.5 2.0 4.0 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Lactamase_B_6 PF16661.5 RUS90562.1 - 1.9e-35 122.1 0.0 3.7e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 RUS90562.1 - 3.4e-34 118.5 0.0 6.4e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 RUS90562.1 - 2.6e-19 69.5 0.0 6e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 RUS90562.1 - 1.9e-14 53.3 0.0 4.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 RUS90562.1 - 7.5e-05 22.8 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SRP54 PF00448.22 RUS90562.1 - 0.021 14.4 0.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Lactamase_B_2 PF12706.7 RUS90562.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain 7tm_1 PF00001.21 RUS90563.1 - 7.3e-41 140.2 26.5 9.2e-41 139.9 26.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS90563.1 - 3.9e-13 49.4 22.4 4.8e-13 49.1 22.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS90563.1 - 2.4e-05 24.2 18.0 3.2e-05 23.8 18.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS90563.1 - 0.0019 17.9 19.4 0.0019 17.9 19.4 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Acyl-CoA_dh_1 PF00441.24 RUS90564.1 - 6.7e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RUS90564.1 - 4.9e-27 94.8 0.0 1.2e-26 93.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RUS90564.1 - 1.2e-20 73.5 0.0 2.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RUS90564.1 - 0.00011 22.5 0.1 0.015 15.6 0.0 2.5 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain DnaJ PF00226.31 RUS90565.1 - 1.1e-25 89.5 0.6 1.1e-25 89.5 0.6 2.8 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 RUS90565.1 - 1.7e-08 34.6 5.4 1.7e-08 34.6 5.4 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS90565.1 - 1.8e-06 28.2 9.1 0.0022 18.3 0.1 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RUS90565.1 - 6.5e-06 26.4 3.7 6.5e-06 26.4 3.7 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RUS90565.1 - 0.00088 19.9 6.8 0.074 13.9 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 RUS90565.1 - 0.78 10.2 13.2 0.17 12.3 0.5 4.3 4 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 RUS90565.1 - 2 9.0 9.8 1.4 9.5 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 RUS90565.1 - 3 8.0 6.9 0.3 11.2 0.4 2.6 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 RUS90565.1 - 3.9 7.6 9.7 2.2 8.4 2.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger SprT-like PF10263.9 RUS90566.1 - 8.4e-26 90.1 0.0 2.1e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 SprT-like family zf_UBZ PF18439.1 RUS90566.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PDZ PF00595.24 RUS90567.1 - 0.00032 21.0 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS90567.1 - 0.0032 17.8 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS90567.1 - 0.0032 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pap_E4 PF02711.14 RUS90567.1 - 0.026 15.5 0.5 0.035 15.1 0.5 1.1 1 0 0 1 1 1 0 E4 protein CAP PF00188.26 RUS90568.1 - 9.2e-20 71.8 0.2 1.6e-19 71.0 0.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PMP22_Claudin PF00822.20 RUS90569.1 - 4.8e-15 55.8 6.0 7.1e-15 55.3 6.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 RUS90569.1 - 1.1e-13 51.4 8.7 1.1e-07 31.8 2.4 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 RUS90569.1 - 1.7 8.1 6.6 0.27 10.7 1.3 2.0 2 1 0 2 2 2 0 Clc-like 7tm_1 PF00001.21 RUS90570.1 - 2.5e-37 128.6 17.7 3.4e-37 128.2 17.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS90570.1 - 1.7e-15 57.5 15.6 2.2e-15 57.1 15.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS90570.1 - 1.7e-08 34.4 17.7 3.1e-08 33.6 17.0 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 RUS90570.1 - 0.00039 19.9 22.4 0.0029 17.0 22.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.8 RUS90570.1 - 0.45 10.3 11.3 0.016 15.0 5.1 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF5527 PF17665.1 RUS90570.1 - 3 7.4 7.3 3.4 7.2 0.8 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5527) WD40 PF00400.32 RUS90571.1 - 7.3e-08 33.0 2.8 0.12 13.3 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Sec16_C PF12931.7 RUS90571.1 - 0.00034 20.4 0.5 0.028 14.1 0.5 2.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Nic96 PF04097.14 RUS90571.1 - 0.17 10.3 0.0 0.93 7.9 0.0 1.9 2 0 0 2 2 2 0 Nup93/Nic96 Peptidase_C14 PF00656.22 RUS90572.1 - 6.9e-52 176.9 0.0 8.2e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Vault PF01505.18 RUS90572.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Major Vault Protein repeat domain Fer2_2 PF01799.20 RUS90573.1 - 1.5e-31 108.3 3.3 6.3e-31 106.2 0.1 2.3 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 RUS90573.1 - 2.6e-07 30.5 0.8 2.6e-07 30.5 0.8 2.4 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 RUS90574.1 - 3.4e-130 435.1 0.3 4.9e-130 434.6 0.3 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 RUS90574.1 - 3e-29 100.9 0.2 3e-29 100.9 0.2 2.4 2 0 0 2 2 2 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 RUS90574.1 - 1.5e-24 86.5 0.0 3.1e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 RUS90574.1 - 5.1e-24 84.9 0.0 1.2e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 RUS90574.1 - 1.1e-22 80.1 0.0 4.2e-22 78.3 0.0 2.1 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 RUS90574.1 - 1.1e-06 28.4 1.3 2.6e-06 27.3 1.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-H2C2_2 PF13465.6 RUS90575.1 - 9.9e-39 130.1 75.7 3.5e-09 36.7 1.7 10.8 10 1 0 10 10 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 RUS90575.1 - 6e-33 111.5 87.8 1.1e-05 25.7 0.7 10.6 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS90575.1 - 1.2e-28 97.3 84.1 0.00027 21.5 1.0 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RUS90575.1 - 3e-10 39.9 7.3 4.6e-05 23.3 0.3 9.2 9 0 0 9 9 9 4 C2H2-type zinc finger BolA PF01722.18 RUS90575.1 - 1.2e-09 38.3 14.7 0.06 13.6 0.2 6.0 3 2 1 4 4 4 3 BolA-like protein zf-Di19 PF05605.12 RUS90575.1 - 0.001 19.3 6.5 0.001 19.3 6.5 6.4 4 2 4 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 RUS90575.1 - 0.0046 16.7 1.6 0.0046 16.7 1.6 7.8 9 0 0 9 9 8 4 zinc-finger C2H2-type zf-met PF12874.7 RUS90575.1 - 0.0054 17.1 3.6 0.049 14.0 0.2 9.5 11 0 0 11 11 10 4 Zinc-finger of C2H2 type GAGA PF09237.11 RUS90575.1 - 0.0062 16.3 29.6 0.16 11.8 0.7 6.8 3 2 5 8 8 8 3 GAGA factor zf-BED PF02892.15 RUS90575.1 - 0.045 13.8 0.8 0.045 13.8 0.8 8.6 6 2 3 9 9 8 0 BED zinc finger zf-C2H2_jaz PF12171.8 RUS90575.1 - 0.082 13.2 0.3 0.082 13.2 0.3 9.3 11 0 0 11 11 9 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 RUS90575.1 - 1.6 8.8 28.6 1.2 9.2 1.5 6.2 6 1 0 6 6 6 0 Adenylate kinase, active site lid RVT_1 PF00078.27 RUS90577.1 - 7.7e-20 71.4 0.6 1.8e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 RUS90578.1 - 0.14 12.2 2.4 0.48 10.5 2.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Zona_pellucida PF00100.23 RUS90579.1 - 3.3e-28 99.2 0.0 3.3e-28 99.2 0.0 2.3 1 1 1 2 2 2 1 Zona pellucida-like domain Glyco_hydro_18 PF00704.28 RUS90580.1 - 4.2e-40 138.4 0.0 6.2e-33 114.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CDC45 PF02724.14 RUS90580.1 - 0.0095 14.3 1.6 0.015 13.6 1.6 1.2 1 0 0 1 1 1 1 CDC45-like protein CENP-B_dimeris PF09026.10 RUS90580.1 - 0.64 10.4 15.6 1.2 9.5 15.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 RUS90580.1 - 1.9 6.6 12.7 2.7 6.1 12.7 1.1 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.22 RUS90582.1 - 7.2e-37 126.5 0.0 9.2e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS90582.1 - 2.8e-14 53.4 0.0 4.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS90582.1 - 4e-10 39.4 0.0 5.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RUS90582.1 - 1.2e-05 25.3 0.1 0.15 12.0 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RUS90582.1 - 2e-05 24.3 0.1 0.00034 20.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS90582.1 - 0.00054 20.0 0.0 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS90582.1 - 0.0081 16.6 0.1 0.017 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 RUS90582.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 RUS90582.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS90582.1 - 0.028 13.6 0.0 2.2 7.4 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 RUS90582.1 - 0.041 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 RUS90582.1 - 0.043 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RUS90582.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RUS90582.1 - 0.066 12.4 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 RUS90582.1 - 0.087 13.1 0.1 0.23 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 RUS90582.1 - 0.088 12.1 0.2 0.71 9.1 0.0 2.0 1 1 1 2 2 2 0 Septin TniB PF05621.11 RUS90582.1 - 0.094 12.1 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Pox_A32 PF04665.12 RUS90582.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 RUS90582.1 - 0.18 11.5 0.8 3.3 7.4 0.1 2.5 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein Syndecan PF01034.20 RUS90583.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain TIL PF01826.17 RUS90583.1 - 0.17 12.2 26.6 1.1 9.6 7.0 2.3 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Lectin_C PF00059.21 RUS90584.1 - 3.1e-23 82.6 0.2 3.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Lectin C-type domain SapB_1 PF05184.15 RUS90585.1 - 9.7e-22 76.6 18.5 0.00069 19.6 0.0 8.9 8 0 0 8 8 8 7 Saposin-like type B, region 1 SapB_2 PF03489.17 RUS90585.1 - 7.8e-21 73.9 26.3 2e-05 24.6 0.0 8.1 7 0 0 7 7 7 5 Saposin-like type B, region 2 TetR_C_5 PF08360.11 RUS90585.1 - 0.011 15.9 0.1 0.04 14.1 0.0 1.9 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Thioredoxin_3 PF13192.6 RUS90585.1 - 0.042 13.9 2.4 46 4.2 0.0 4.8 5 0 0 5 5 5 0 Thioredoxin domain TetR_C_10 PF16295.5 RUS90585.1 - 0.11 12.8 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IBD PF10416.9 RUS90585.1 - 0.65 10.0 1.8 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Autophagy_C PF10381.9 RUS90585.1 - 6.9 6.3 7.1 23 4.6 0.1 3.0 3 0 0 3 3 3 0 Autophagocytosis associated protein C-terminal VHS PF00790.19 RUS90586.1 - 1.4e-42 144.9 0.0 1.6e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 RUS90586.1 - 0.0017 18.4 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain Fer4_8 PF13183.6 RUS90586.1 - 0.022 15.2 1.1 0.04 14.4 1.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Exog_C PF18026.1 RUS90586.1 - 0.18 11.9 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain GAT PF03127.14 RUS90587.1 - 4.1e-11 43.0 1.2 1.2e-10 41.6 1.2 1.7 1 0 0 1 1 1 1 GAT domain USP8_dimer PF08969.11 RUS90588.1 - 4.9e-19 68.6 0.3 4.9e-19 68.6 0.3 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.21 RUS90588.1 - 2.8e-10 40.2 6.6 6e-10 39.1 0.3 3.0 2 2 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 RUS90588.1 - 0.00013 21.7 1.0 0.00026 20.8 0.0 2.0 2 1 0 2 2 2 1 Prokaryotic homologs of the JAB domain CAF-1_p150 PF11600.8 RUS90588.1 - 0.022 14.5 23.1 0.042 13.5 23.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MADF_DNA_bdg PF10545.9 RUS90589.1 - 7.4e-18 64.7 6.3 1.5e-17 63.7 6.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS90589.1 - 2.9e-05 23.8 1.8 3.5e-05 23.5 0.3 1.9 2 0 0 2 2 2 1 BESS motif DUF2236 PF09995.9 RUS90589.1 - 0.045 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) CARD PF00619.21 RUS90590.1 - 1.1e-06 28.6 1.0 3.1e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 Caspase recruitment domain ADIP PF11559.8 RUS90590.1 - 0.0053 16.9 8.4 0.0094 16.0 8.0 1.5 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 RUS90590.1 - 0.0053 16.8 8.9 0.23 11.5 6.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 RUS90590.1 - 0.0099 14.8 6.0 0.018 14.0 6.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_23 PF13476.6 RUS90590.1 - 0.02 15.4 0.3 0.027 15.0 0.3 1.2 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 RUS90590.1 - 0.033 13.7 3.7 0.046 13.2 3.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 RUS90590.1 - 0.04 14.3 5.2 5.8 7.4 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) XLF PF09302.11 RUS90590.1 - 0.052 13.7 1.5 0.34 11.0 1.6 2.0 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component BLOC1_2 PF10046.9 RUS90590.1 - 0.064 13.6 7.4 6.1 7.2 6.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.14 RUS90590.1 - 0.068 12.9 2.5 0.21 11.3 0.8 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain SOGA PF11365.8 RUS90590.1 - 0.071 14.2 6.5 6.3 8.0 7.0 2.4 1 1 1 2 2 2 0 Protein SOGA DUF3450 PF11932.8 RUS90590.1 - 0.25 10.6 8.5 0.26 10.6 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5082 PF16888.5 RUS90590.1 - 0.28 11.5 7.2 4.3 7.6 6.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3847 PF12958.7 RUS90590.1 - 0.43 10.7 6.6 0.13 12.4 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) XhlA PF10779.9 RUS90590.1 - 1.3 9.3 9.0 2.7 8.3 4.4 2.7 1 1 2 3 3 3 0 Haemolysin XhlA DivIC PF04977.15 RUS90590.1 - 1.4 8.8 8.8 1.4 8.7 4.3 2.9 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 RUS90590.1 - 1.5 9.0 5.9 2.5 8.3 5.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 RUS90590.1 - 3.6 8.0 8.7 11 6.4 1.3 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4094 PF13334.6 RUS90590.1 - 4.2 7.8 6.1 1.3e+02 3.1 6.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF724 PF05266.14 RUS90590.1 - 8 6.2 8.3 13 5.6 7.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) RA PF00788.23 RUS90591.1 - 1.1e-11 45.2 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LIM PF00412.22 RUS90591.1 - 4.4e-10 39.6 2.7 6.9e-10 39.0 0.4 2.1 2 0 0 2 2 2 1 LIM domain Nore1-SARAH PF16517.5 RUS90591.1 - 2.3e-05 24.2 0.3 6.8e-05 22.7 0.3 1.8 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf_C2HC_14 PF18574.1 RUS90591.1 - 1.4 8.7 4.3 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain Y_phosphatase PF00102.27 RUS90592.1 - 2.7e-65 220.2 0.0 4.9e-65 219.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 RUS90592.1 - 1.7e-32 111.6 0.2 3.5e-12 46.5 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 RUS90592.1 - 2.3e-21 75.4 2.4 1.8e-09 37.3 0.1 4.0 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 RUS90592.1 - 1.4e-14 54.1 0.2 5.9e-05 23.3 0.1 3.8 3 0 0 3 3 3 3 PDZ domain Y_phosphatase3 PF13350.6 RUS90592.1 - 0.0039 17.2 0.2 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family TFIIA PF03153.13 RUS90592.1 - 0.068 13.2 23.5 0.066 13.2 15.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DSPc PF00782.20 RUS90592.1 - 0.071 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MID_MedPIWI PF18296.1 RUS90592.1 - 0.47 10.2 10.4 4.6 7.0 0.2 2.4 2 0 0 2 2 2 0 MID domain of medPIWI FERM_M PF00373.18 RUS90593.1 - 1e-20 74.3 0.0 3.1e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.24 RUS90593.1 - 5.1e-17 62.0 0.2 9.6e-17 61.1 0.2 1.5 1 0 0 1 1 1 1 PDZ domain KIND PF16474.5 RUS90593.1 - 7.9e-12 45.5 0.1 1.7e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain FERM_N PF09379.10 RUS90593.1 - 6.6e-11 42.0 0.0 2.8e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain PDZ_6 PF17820.1 RUS90593.1 - 2.6e-10 40.0 0.0 7.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain FERM_C PF09380.10 RUS90593.1 - 6.5e-10 39.3 0.2 1.3e-09 38.4 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain IP_trans PF02121.18 RUS90594.1 - 1.8e-112 374.9 1.0 2e-112 374.7 1.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PRELI PF04707.14 RUS90594.1 - 0.0022 17.8 0.1 0.0097 15.7 0.0 2.0 1 1 1 2 2 2 1 PRELI-like family Dpy-30 PF05186.13 RUS90595.1 - 6.3e-09 35.4 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif SH3_9 PF14604.6 RUS90596.1 - 1.2e-43 146.7 9.4 4.3e-14 52.1 0.4 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 RUS90596.1 - 1.2e-36 124.1 3.7 5.4e-13 48.4 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 RUS90596.1 - 1.6e-36 123.7 10.7 1.3e-11 44.0 0.3 3.3 3 0 0 3 3 3 3 SH3 domain MOSC PF03473.17 RUS90597.1 - 2.4e-27 95.5 0.0 6e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 RUS90597.1 - 4.6e-08 32.9 0.0 6.4e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 MOSC N-terminal beta barrel domain Tachystatin_B PF11478.8 RUS90597.1 - 0.0014 18.5 0.3 0.0014 18.5 0.3 4.6 3 1 3 7 7 7 1 Antimicrobial chitin binding protein tachystatin B SNase PF00565.17 RUS90599.1 - 2.1e-68 227.6 0.3 7.8e-19 68.1 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 RUS90599.1 - 1.2e-29 102.9 0.0 3.1e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 RUS90599.1 - 0.00083 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 RUS90599.1 - 0.048 14.1 0.3 0.57 10.7 0.0 2.9 2 1 0 2 2 2 0 Agenet domain Flg_hook PF02120.16 RUS90599.1 - 0.12 12.3 0.6 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK WD40 PF00400.32 RUS90600.1 - 9e-10 39.0 7.8 0.031 15.1 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF726 PF05277.12 RUS90600.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) STI1 PF17830.1 RUS90601.1 - 5e-11 42.4 5.2 6e-06 26.1 0.1 3.7 2 1 0 2 2 2 2 STI1 domain Med9 PF07544.13 RUS90601.1 - 0.38 10.9 3.1 0.52 10.4 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Copine PF07002.16 RUS90602.1 - 3.6e-86 288.1 0.0 4.8e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 RUS90602.1 - 1.1e-28 99.5 0.0 7.6e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 RUS90602.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Sugarporin_N PF11471.8 RUS90605.1 - 0.00024 21.0 0.8 0.00044 20.1 0.8 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension FucT_N PF18025.1 RUS90606.1 - 0.00036 20.9 1.7 46 4.5 0.0 4.8 2 1 5 7 7 7 5 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain PLDc PF00614.22 RUS90606.1 - 0.018 15.2 16.7 4.8e+02 1.2 0.0 10.4 12 0 0 12 12 12 0 Phospholipase D Active site motif Fam20C PF06702.12 RUS90609.1 - 8.3e-05 22.5 0.6 0.0079 16.0 0.6 2.2 1 1 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 Corona_NS2 PF04753.12 RUS90609.1 - 0.049 14.2 0.1 0.096 13.3 0.1 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 OrfA PF17495.2 RUS90610.1 - 0.00097 19.3 0.1 0.62 10.3 0.0 2.3 2 0 0 2 2 2 2 Vpr-like OrfA DNA_photolyase PF00875.18 RUS90611.1 - 1.4 8.9 7.1 47 3.9 0.1 3.6 1 1 3 4 4 4 0 DNA photolyase SF3A3 PF16837.5 RUS90611.1 - 7.3 7.2 20.6 3.1e+03 -1.2 20.6 3.0 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF1500 PF07389.12 RUS90611.1 - 9.1 6.4 12.2 31 4.7 1.2 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1500) RabGAP-TBC PF00566.18 RUS90612.1 - 7.4e-47 159.8 5.5 1e-46 159.3 5.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 RUS90612.1 - 4.3e-29 101.2 0.0 6.6e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Rab-binding domain (RBD) Tubulin PF00091.25 RUS90613.1 - 2e-67 227.2 0.0 2.7e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS90613.1 - 3.7e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS90613.1 - 0.00079 19.2 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L13 PF00572.18 RUS90614.1 - 2.1e-05 24.8 1.1 0.16 12.2 0.0 3.1 1 1 1 2 2 2 2 Ribosomal protein L13 NifU_N PF01592.16 RUS90615.1 - 1.2e-56 190.4 0.1 1.4e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain zf-RING_14 PF17978.1 RUS90617.1 - 7.3e-38 128.9 7.7 7.3e-38 128.9 7.7 2.7 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain IBR PF01485.21 RUS90617.1 - 3.1e-14 52.9 44.5 6.5e-09 35.9 1.8 3.8 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Aminotran_5 PF00266.19 RUS90617.1 - 0.24 10.3 0.0 0.88 8.5 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V FidL_like PF15941.5 RUS90620.1 - 8.8 6.9 10.6 45 4.6 1.6 3.0 1 1 1 2 2 2 0 FidL-like putative membrane protein Ion_trans PF00520.31 RUS90621.1 - 1.9e-17 63.3 15.2 2.9e-17 62.7 15.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RUS90621.1 - 2.7e-08 34.3 0.0 5.4e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS90621.1 - 1e-06 28.9 0.2 0.00038 20.7 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 RUS90621.1 - 6.8e-06 25.0 9.4 6.8e-06 25.0 9.4 1.7 1 1 1 2 2 2 1 Polycystin cation channel Ank_4 PF13637.6 RUS90621.1 - 8e-06 26.3 0.1 0.00029 21.3 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS90621.1 - 4.5e-05 23.7 0.1 0.024 15.1 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 RUS90621.1 - 0.00024 21.3 0.1 0.12 13.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat RVT_1 PF00078.27 RUS90622.1 - 1.6e-19 70.3 2.0 4.4e-09 36.2 0.1 3.4 3 1 1 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) UvrA_DNA-bind PF17755.1 RUS90622.1 - 0.1 13.0 1.2 15 5.9 0.0 2.8 2 0 0 2 2 2 0 UvrA DNA-binding domain DNA_pol_B PF00136.21 RUS90623.1 - 1.1e-25 90.3 0.0 1.6e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 RUS90623.1 - 8.6e-20 71.0 9.2 1.6e-19 70.1 9.2 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 RUS90623.1 - 0.047 13.7 1.6 0.047 13.7 1.6 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 RUS90623.1 - 0.052 13.0 3.9 0.13 11.7 3.9 1.7 1 0 0 1 1 1 0 zinc-ribbon domain C1_1 PF00130.22 RUS90623.1 - 3 7.8 10.0 76 3.3 10.0 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UAE_UbL PF14732.6 RUS90624.1 - 0.071 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Tubulin PF00091.25 RUS90625.1 - 1e-68 231.5 0.0 1.3e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS90625.1 - 2.1e-49 166.9 0.0 3.4e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS90625.1 - 0.00085 19.1 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RUS90625.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Ets PF00178.22 RUS90627.1 - 9.1e-32 109.4 1.3 1.5e-31 108.7 1.3 1.3 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 RUS90627.1 - 1.3e-12 47.5 0.1 2.5e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CDC45 PF02724.14 RUS90628.1 - 5.9e-05 21.6 7.5 6.7e-05 21.4 7.5 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 RUS90628.1 - 0.0034 17.6 8.3 0.0042 17.3 8.3 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Mpp10 PF04006.12 RUS90628.1 - 0.015 13.8 6.6 0.017 13.6 6.6 1.0 1 0 0 1 1 1 0 Mpp10 protein Sporozoite_P67 PF05642.11 RUS90628.1 - 0.025 12.7 6.4 0.032 12.3 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 RUS90628.1 - 0.033 13.6 12.1 0.039 13.4 12.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS90628.1 - 0.034 12.4 13.3 0.04 12.2 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS90628.1 - 0.058 11.7 3.9 0.065 11.5 3.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.12 RUS90628.1 - 0.08 12.3 11.6 0.11 11.9 11.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 RUS90628.1 - 0.19 11.7 12.9 0.4 10.7 12.2 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 RUS90628.1 - 0.26 9.4 28.5 0.33 9.0 28.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 RUS90628.1 - 0.64 8.4 7.5 0.65 8.4 7.5 1.1 1 0 0 1 1 1 0 SGT1 protein CNDH2_C PF16858.5 RUS90628.1 - 1 9.1 6.1 1.3 8.9 6.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4887 PF16228.5 RUS90628.1 - 1.5 9.0 12.4 1.9 8.6 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) PPP4R2 PF09184.11 RUS90628.1 - 4.8 6.7 16.0 6.6 6.2 16.0 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 RUS90628.1 - 6.4 6.0 17.0 7.9 5.7 17.0 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 RUS90628.1 - 6.5 6.4 7.3 9 5.9 7.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 RUS90628.1 - 7.4 5.8 31.5 11 5.2 31.5 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 RUS90628.1 - 9.1 6.0 10.3 17 5.1 10.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH MINDY_DUB PF04424.13 RUS90629.1 - 1.6e-38 131.3 0.1 2.6e-38 130.6 0.1 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase RseA_C PF03873.13 RUS90629.1 - 6 7.2 13.4 0.34 11.2 6.3 2.8 2 1 1 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain BTD PF09270.10 RUS90631.1 - 3.8e-74 248.0 0.0 9.3e-74 246.7 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 RUS90631.1 - 3.3e-49 167.4 0.2 3.3e-49 167.4 0.2 3.1 3 0 0 3 3 3 1 LAG1, DNA binding MFS_1 PF07690.16 RUS90632.1 - 6.6e-11 41.7 28.4 0.0083 15.1 0.0 4.1 4 0 0 4 4 4 3 Major Facilitator Superfamily Pax2_C PF12403.8 RUS90632.1 - 6.9e-05 22.9 3.8 0.45 10.6 0.8 3.9 1 1 2 3 3 3 3 Paired-box protein 2 C terminal SlyX PF04102.12 RUS90632.1 - 0.2 12.3 0.0 19 5.9 0.0 2.4 1 1 1 2 2 2 0 SlyX DnaJ_CXXCXGXG PF00684.19 RUS90632.1 - 2.4 8.6 8.0 13 6.2 3.9 2.6 1 1 1 2 2 2 0 DnaJ central domain Lyase_8_C PF02884.17 RUS90633.1 - 0.09 13.3 0.2 1.5e+02 2.9 0.0 4.1 2 2 1 3 3 3 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain MDH PF02315.16 RUS90634.1 - 0.042 13.9 0.8 0.28 11.3 0.8 2.5 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Kinesin PF00225.23 RUS90635.1 - 3e-102 342.0 0.9 3e-102 342.0 0.9 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 RUS90635.1 - 2.2e-19 69.9 0.8 6.2e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 Microtubule binding TSC22 PF01166.18 RUS90635.1 - 0.003 17.8 7.6 0.038 14.3 0.0 3.8 3 1 1 4 4 4 1 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 RUS90635.1 - 0.0057 16.7 6.2 0.0057 16.7 6.2 3.1 2 1 1 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bcr-Abl_Oligo PF09036.10 RUS90635.1 - 0.029 14.4 1.8 0.26 11.3 0.3 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 RUS90635.1 - 0.048 12.5 15.5 0.52 9.1 9.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Synaptobrevin PF00957.21 RUS90635.1 - 0.07 12.9 4.5 0.65 9.8 2.0 3.3 4 0 0 4 4 4 0 Synaptobrevin DUF3450 PF11932.8 RUS90635.1 - 0.15 11.3 10.5 0.082 12.2 4.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) TACC_C PF05010.14 RUS90635.1 - 0.27 11.0 14.9 2.8 7.7 9.5 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4407 PF14362.6 RUS90635.1 - 0.36 10.1 5.5 0.59 9.4 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 RUS90635.1 - 0.5 10.8 12.3 3.7 8.0 0.5 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 RUS90635.1 - 0.7 10.5 13.7 4.2 8.1 0.6 3.3 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PspA_IM30 PF04012.12 RUS90635.1 - 0.73 9.4 9.9 3.5 7.1 2.5 3.0 2 1 1 3 3 3 0 PspA/IM30 family OmpH PF03938.14 RUS90635.1 - 0.85 10.0 9.3 0.91 9.9 0.7 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Med9 PF07544.13 RUS90635.1 - 0.93 9.6 10.8 1.6 8.9 0.9 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1192 PF06698.11 RUS90635.1 - 1.1 9.3 9.2 1.1 9.3 0.4 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) HrpB7 PF09486.10 RUS90635.1 - 1.3 9.4 5.9 0.49 10.8 0.8 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 RUS90635.1 - 1.3 9.1 7.3 1.7 8.7 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 RUS90635.1 - 1.4 9.1 9.1 6.3 7.0 1.3 3.6 2 1 0 2 2 2 0 Swi5 BST2 PF16716.5 RUS90635.1 - 1.6 9.3 12.4 5.4 7.7 4.5 3.3 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 RUS90635.1 - 2.2 8.7 17.2 0.93 9.9 2.0 2.5 2 1 1 3 3 2 0 Fez1 Cob_adeno_trans PF01923.18 RUS90635.1 - 2.4 8.3 7.1 4.6 7.4 1.6 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase USP8_interact PF08941.10 RUS90635.1 - 2.4 7.9 7.6 0.71 9.7 1.1 2.4 2 1 0 2 2 2 0 USP8 interacting TMF_DNA_bd PF12329.8 RUS90635.1 - 2.8 8.0 10.6 1.4 9.0 3.8 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 RUS90635.1 - 5.5 6.1 11.1 3.5 6.8 7.2 2.4 1 1 1 2 2 2 0 TMPIT-like protein MPS2 PF17060.5 RUS90635.1 - 6.6 5.9 12.4 0.23 10.7 3.5 2.4 2 1 1 3 3 3 0 Monopolar spindle protein 2 MCM PF00493.23 RUS90636.1 - 6e-100 333.0 0.3 2.2e-51 174.1 0.1 2.5 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 RUS90636.1 - 3.2e-24 85.2 1.0 8.6e-24 83.8 1.0 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS90636.1 - 1.5e-15 57.3 1.8 4.8e-15 55.7 1.8 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RUS90636.1 - 8.8e-12 44.8 0.8 4.3e-05 23.0 0.0 3.8 2 1 2 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RUS90636.1 - 9.1e-11 41.9 0.0 2.8e-06 27.4 0.0 2.9 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RUS90636.1 - 6.4e-06 26.1 0.0 0.095 12.6 0.0 2.7 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RUS90636.1 - 0.00025 20.8 0.1 2.5 7.8 0.0 3.4 1 1 1 2 2 2 2 Sigma-54 interaction domain DUF4604 PF15377.6 RUS90638.1 - 0.02 15.3 18.3 0.028 14.9 18.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) ETRAMP PF09716.10 RUS90638.1 - 0.14 12.2 7.9 0.2 11.7 7.9 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OAD_gamma PF04277.13 RUS90638.1 - 0.95 10.1 4.8 1.9 9.2 4.8 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RR_TM4-6 PF06459.12 RUS90638.1 - 1.8 8.3 11.8 2.4 7.9 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5401 PF17380.2 RUS90638.1 - 2.6 6.0 14.3 3.1 5.8 14.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SRCR PF00530.18 RUS90639.1 - 0.064 13.8 1.0 0.11 13.0 0.2 1.8 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain zf-CXXC PF02008.20 RUS90642.1 - 1.6e-07 31.2 21.4 5e-07 29.6 21.4 1.9 1 0 0 1 1 1 1 CXXC zinc finger domain Sulfotransfer_1 PF00685.27 RUS90644.1 - 7.6e-25 87.9 0.0 1.1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS90644.1 - 1.6e-13 51.6 0.0 8e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS90644.1 - 0.0094 15.9 0.1 0.03 14.2 0.1 1.6 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS90645.1 - 3.7e-19 69.3 0.0 4.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS90645.1 - 9.4e-11 42.5 0.0 0.00056 20.4 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS90645.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family COesterase PF00135.28 RUS90646.1 - 4.3e-140 468.0 0.0 4.9e-140 467.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS90646.1 - 3.8e-09 36.7 0.0 8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2236 PF09995.9 RUS90648.1 - 3.1e-17 63.5 0.0 3.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Cpn60_TCP1 PF00118.24 RUS90649.1 - 3.2e-27 95.3 0.0 4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 RUS90650.1 - 0.017 13.8 0.0 0.85 8.2 0.0 2.1 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family DUF2379 PF09543.10 RUS90650.1 - 0.23 11.7 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Cofilin_ADF PF00241.20 RUS90651.1 - 2.5e-27 95.1 2.0 2.8e-27 94.9 2.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ThiF PF00899.21 RUS90652.1 - 3.8e-36 124.7 0.0 4.8e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family TMEM223 PF14640.6 RUS90653.1 - 2.2e-45 154.8 0.1 3.2e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 Annexin PF00191.20 RUS90654.1 - 3e-241 780.0 39.5 1.5e-22 79.4 0.1 13.2 13 0 0 13 13 13 13 Annexin DUF2019 PF09450.10 RUS90654.1 - 0.0011 18.9 5.4 2.4 8.2 0.0 6.1 7 0 0 7 7 7 2 Domain of unknown function (DUF2019) PX PF00787.24 RUS90654.1 - 0.033 14.2 0.0 10 6.1 0.0 3.0 2 0 0 2 2 2 0 PX domain partial_CstF PF15861.5 RUS90654.1 - 0.088 12.6 0.0 2.2 8.1 0.0 3.1 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain GST_N PF02798.20 RUS90655.1 - 1.2e-18 67.2 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RUS90655.1 - 3.9e-10 40.0 0.0 5.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS90655.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 RUS90655.1 - 0.035 14.4 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein LicD PF04991.13 RUS90656.1 - 4.5e-13 49.9 2.7 3.3e-11 43.8 2.5 2.2 1 1 1 2 2 2 2 LicD family 7tm_1 PF00001.21 RUS90657.1 - 2.7e-07 30.2 1.5 3.2e-07 30.0 1.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS90657.1 - 0.033 13.6 0.4 0.038 13.3 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_1 PF00001.21 RUS90658.1 - 5.6e-05 22.6 0.0 8.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CENP-B_dimeris PF09026.10 RUS90658.1 - 0.011 16.1 18.3 0.02 15.3 18.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RUS90658.1 - 0.044 11.9 13.2 0.059 11.5 13.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 RUS90658.1 - 0.069 13.2 2.6 0.1 12.6 2.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 RUS90658.1 - 0.22 10.0 2.8 0.29 9.6 2.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 RUS90658.1 - 0.48 10.1 1.2 0.78 9.4 1.2 1.3 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 RUS90658.1 - 0.54 9.9 17.7 0.75 9.5 17.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 RUS90658.1 - 2.9 7.4 7.5 4.4 6.8 7.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Spc7_N PF15402.6 RUS90658.1 - 9.1 4.4 7.0 12 4.0 7.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Sushi PF00084.20 RUS90659.1 - 1.2e-18 67.5 12.9 1.2e-09 38.7 0.8 6.0 4 2 1 5 5 5 4 Sushi repeat (SCR repeat) HRM PF02793.22 RUS90659.1 - 0.21 11.9 7.6 3.4 8.0 0.2 4.1 4 0 0 4 4 4 0 Hormone receptor domain MFS_1 PF07690.16 RUS90660.1 - 4.8e-32 111.3 36.3 6.4e-32 110.9 36.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_10 PF00852.19 RUS90661.1 - 5.7e-43 146.7 0.2 7.8e-43 146.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS90661.1 - 1.3e-09 38.5 0.1 2.7e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Hormone_3 PF00159.18 RUS90661.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide Glyco_transf_10 PF00852.19 RUS90662.1 - 2.8e-43 147.7 1.9 5e-43 146.9 1.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS90662.1 - 5.5e-07 30.0 0.1 1.3e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Peptidase_S64 PF08192.11 RUS90662.1 - 2.7 6.4 11.9 3.7 5.9 11.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 7TM_GPCR_Srx PF10328.9 RUS90663.1 - 9.9e-08 31.9 8.7 9.9e-08 31.9 8.7 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS90663.1 - 5.2e-06 26.0 7.0 1e-05 25.0 7.0 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.15 RUS90663.1 - 0.028 14.4 3.1 0.059 13.4 3.1 1.7 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srbc PF10316.9 RUS90663.1 - 0.051 13.1 11.5 0.25 10.8 11.5 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc Glyco_transf_10 PF00852.19 RUS90664.1 - 7.9e-35 120.2 0.1 9e-35 120.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term CBM_14 PF01607.24 RUS90665.1 - 2.3e-08 34.1 1.4 3.1e-08 33.7 1.4 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain AJAP1_PANP_C PF15298.6 RUS90665.1 - 0.084 13.1 7.0 0.094 12.9 7.0 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF1168 PF06658.12 RUS90666.1 - 4.5e-44 149.6 17.5 7.3e-44 148.9 17.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Hid1 PF12722.7 RUS90666.1 - 8.3 4.4 7.6 11 4.0 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1647 PF07801.11 RUS90667.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Fibrinogen_C PF00147.18 RUS90668.1 - 7e-65 218.9 9.4 1.1e-64 218.3 9.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF2664 PF10867.8 RUS90668.1 - 0.082 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Mucin PF01456.17 RUS90668.1 - 0.49 10.4 9.2 0.084 12.9 5.3 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Laminin_II PF06009.12 RUS90668.1 - 0.69 9.9 3.3 6.4 6.8 0.1 2.8 1 1 2 3 3 3 0 Laminin Domain II DUF4798 PF16055.5 RUS90668.1 - 1.5 9.1 9.4 0.44 10.8 4.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4798) Presenilin PF01080.17 RUS90669.1 - 0.75 8.5 16.3 1.3 7.7 16.3 1.4 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 RUS90669.1 - 2.9 6.6 13.9 4.8 5.9 13.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Menin PF05053.13 RUS90669.1 - 5.8 5.2 20.6 8.1 4.7 20.6 1.2 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 RUS90669.1 - 7.6 3.5 12.9 9.5 3.2 12.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF442 PF04273.13 RUS90671.1 - 5.4e-11 42.6 0.0 0.005 16.9 0.0 3.4 3 0 0 3 3 3 3 Putative phosphatase (DUF442) DSPc PF00782.20 RUS90671.1 - 0.079 12.8 0.0 3.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain DUF442 PF04273.13 RUS90672.1 - 4.6e-08 33.1 0.0 0.066 13.3 0.0 3.3 3 0 0 3 3 3 3 Putative phosphatase (DUF442) Toprim_2 PF13155.6 RUS90672.1 - 0.0075 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Toprim-like LSM_int_assoc PF16605.5 RUS90674.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 LSM-interacting associated unstructured Coa1 PF08695.10 RUS90674.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Sugar_tr PF00083.24 RUS90675.1 - 2.5e-118 395.8 31.1 4.5e-89 299.4 19.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS90675.1 - 1e-32 113.5 29.2 4.1e-31 108.2 18.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RUS90675.1 - 0.00039 19.0 2.6 0.00069 18.2 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fer2_2 PF01799.20 RUS90675.1 - 0.0043 17.0 2.4 0.33 11.0 0.1 2.6 2 0 0 2 2 2 2 [2Fe-2S] binding domain PSI_integrin PF17205.3 RUS90675.1 - 0.27 11.0 6.1 0.5 10.2 6.1 1.4 1 0 0 1 1 1 0 Integrin plexin domain TPT PF03151.16 RUS90676.1 - 5.9e-16 58.7 14.8 6.7e-16 58.5 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RUS90676.1 - 3.6e-07 30.4 27.6 0.00025 21.2 11.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family Cwf_Cwc_15 PF04889.12 RUS90677.1 - 0.0051 16.6 5.2 0.0068 16.2 5.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 RUS90677.1 - 0.11 11.0 3.2 0.16 10.5 3.2 1.1 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 RUS90677.1 - 0.14 11.4 8.7 0.25 10.6 8.7 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 RUS90677.1 - 0.84 9.6 3.9 1.3 9.0 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3295 PF11702.8 RUS90677.1 - 1.2 8.4 4.9 1.7 7.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CENP-B_dimeris PF09026.10 RUS90677.1 - 6.2 7.3 20.1 41 4.6 20.1 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1899 PF08953.11 RUS90678.1 - 2.8e-31 107.2 0.0 5e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 RUS90678.1 - 6.7e-20 70.7 0.3 1.1e-19 70.0 0.3 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 RUS90678.1 - 1.3e-09 38.5 4.1 9.4e-05 23.1 0.3 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS90678.1 - 5.7e-06 26.5 0.2 0.046 14.0 0.2 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CAT_RBD PF03123.15 RUS90678.1 - 0.014 15.4 0.1 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 CAT RNA binding domain Trimer_CC PF08954.11 RUS90678.1 - 0.063 12.8 2.0 0.15 11.7 2.0 1.5 1 0 0 1 1 1 0 Trimerisation motif Cupin_2 PF07883.11 RUS90679.1 - 2.2e-09 36.9 0.3 3.1e-09 36.4 0.3 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 RUS90679.1 - 0.0072 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_4 PF08007.12 RUS90679.1 - 0.026 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein EutQ PF06249.12 RUS90679.1 - 0.029 14.2 0.0 0.051 13.3 0.0 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 RUS90679.1 - 0.049 13.2 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Clathrin PF00637.20 RUS90680.1 - 2.9e-207 678.9 48.7 5.6e-34 117.1 4.0 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 RUS90680.1 - 1.5e-48 160.8 5.1 9.6e-08 32.0 0.0 6.5 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 RUS90680.1 - 5.4e-33 112.7 0.3 2.7e-32 110.5 0.3 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 RUS90680.1 - 4.1e-11 42.0 0.2 1.2e-10 40.6 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 RUS90680.1 - 2.7e-08 33.3 7.0 3.3e-05 23.1 0.1 4.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 RUS90680.1 - 0.00025 20.9 11.1 1.1 9.5 0.3 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 RUS90680.1 - 0.0046 17.7 9.9 8.3 7.5 0.1 6.8 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS90680.1 - 0.045 13.9 9.8 8.2 6.8 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat CH_2 PF06294.11 RUS90680.1 - 0.045 13.9 0.3 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 CH-like domain in sperm protein TPR_17 PF13431.6 RUS90680.1 - 0.056 13.8 0.3 1.2e+02 3.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RUS90680.1 - 0.083 13.4 10.3 1.4 9.5 0.1 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS90680.1 - 0.13 12.5 6.1 2.3 8.5 0.0 5.4 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RUS90680.1 - 0.95 9.8 8.4 16 6.0 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 RUS90680.1 - 1.1 9.2 0.0 1.1 9.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Actin PF00022.19 RUS90681.1 - 9.7e-102 340.6 0.0 3e-101 339.0 0.0 1.6 1 1 0 1 1 1 1 Actin EST1_DNA_bind PF10373.9 RUS90682.1 - 2e-53 181.7 0.0 4.1e-53 180.7 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 RUS90682.1 - 3e-14 53.8 0.9 1.1e-13 52.0 0.0 2.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_4 PF13638.6 RUS90682.1 - 1.3e-10 41.7 0.0 1.3e-10 41.7 0.0 3.1 1 1 1 2 2 2 1 PIN domain KRAP_IP3R_bind PF14722.6 RUS90682.1 - 0.028 14.1 0.0 0.17 11.6 0.0 2.4 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain baeRF_family12 PF18856.1 RUS90682.1 - 0.058 14.0 0.2 0.058 14.0 0.2 5.7 6 0 0 6 6 6 0 Bacterial archaeo-eukaryotic release factor family 12 UPF0561 PF10573.9 RUS90682.1 - 4.7 7.4 30.5 0.011 15.8 3.4 5.5 5 0 0 5 5 5 0 Uncharacterised protein family UPF0561 RhoGAP PF00620.27 RUS90683.1 - 7.1e-47 159.0 0.1 9.8e-46 155.3 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.20 RUS90683.1 - 3e-35 122.1 4.3 2e-33 116.2 2.6 2.5 1 1 1 2 2 2 2 RhoGEF domain C2 PF00168.30 RUS90683.1 - 1.2e-06 28.8 0.0 3.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain PH PF00169.29 RUS90683.1 - 0.0014 19.1 0.4 0.052 14.1 0.4 2.6 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 RUS90683.1 - 0.052 13.5 0.4 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 PH domain GAS PF13851.6 RUS90683.1 - 1.7 7.9 5.2 1.3 8.4 1.7 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding V-SNARE_C PF12352.8 RUS90684.1 - 0.00018 21.7 12.3 0.004 17.4 4.3 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.12 RUS90684.1 - 0.00081 19.8 3.4 0.66 10.5 0.1 2.8 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF5089 PF17002.5 RUS90684.1 - 0.005 16.7 4.9 0.039 13.8 1.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF5089) DASH_Duo1 PF08651.10 RUS90684.1 - 0.058 13.2 5.5 2.1 8.2 0.6 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 WXG100 PF06013.12 RUS90684.1 - 1.9 8.8 8.4 7.1 6.9 0.7 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Laminin_II PF06009.12 RUS90684.1 - 2.3 8.2 6.2 0.79 9.7 0.1 2.7 3 1 0 3 3 3 0 Laminin Domain II Sec20 PF03908.13 RUS90684.1 - 4.7 7.2 5.9 11 6.0 2.6 2.9 2 1 0 2 2 2 0 Sec20 SpoIIE PF07228.12 RUS90685.1 - 1.6e-13 51.0 0.0 2.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 RUS90685.1 - 2.5e-09 37.1 0.3 7.9e-08 32.2 0.3 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 RUS90685.1 - 1.8e-08 34.4 0.0 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Rad9 PF04139.13 RUS90686.1 - 2.1e-89 299.3 0.5 2.7e-89 298.9 0.5 1.1 1 0 0 1 1 1 1 Rad9 Metallophos_2 PF12850.7 RUS90687.1 - 9e-22 78.0 0.1 1.1e-21 77.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 RUS90687.1 - 0.00034 21.2 0.9 0.068 13.7 0.9 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LXG PF04740.12 RUS90688.1 - 0.0053 16.5 1.6 0.011 15.4 1.6 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily ATG16 PF08614.11 RUS90688.1 - 0.017 15.3 11.0 0.017 15.3 11.0 3.2 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 RUS90688.1 - 3.6 7.7 20.1 0.85 9.7 2.0 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 RUS90688.1 - 5.9 6.2 18.0 0.11 11.8 9.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2937 PF11157.8 RUS90688.1 - 7 6.3 5.3 6.4 6.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Cytochrom_B562 PF07361.11 RUS90688.1 - 7.6 7.3 10.1 0.72 10.5 0.4 2.7 3 0 0 3 3 3 0 Cytochrome b562 LIM PF00412.22 RUS90691.1 - 5.5e-35 119.4 18.9 1.3e-18 66.9 2.4 2.0 2 0 0 2 2 2 2 LIM domain zf-ACC PF17848.1 RUS90691.1 - 2.2 8.4 0.0 2.2 8.4 0.0 4.6 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain BSD PF03909.17 RUS90692.1 - 2.6e-15 56.2 2.3 2.8e-15 56.0 0.6 2.0 2 0 0 2 2 2 1 BSD domain LepA_C PF06421.12 RUS90692.1 - 0.69 10.1 4.0 2.5 8.3 2.8 2.2 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus PAC1 PF16094.5 RUS90693.1 - 1.9e-72 243.8 0.4 2.5e-72 243.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Glyco_hydro_38N PF01074.22 RUS90694.1 - 3.9e-82 275.9 0.0 6.4e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS90694.1 - 3e-40 138.6 0.0 1.2e-35 123.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 RUS90694.1 - 9.4e-21 73.8 0.0 2.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 RUS90694.1 - 2.8e-06 27.3 0.1 9.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_2_N PF02837.18 RUS90694.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ank_2 PF12796.7 RUS90696.1 - 2.4e-19 69.7 2.0 5.1e-10 39.8 0.0 6.7 5 3 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS90696.1 - 1.4e-15 57.5 8.4 0.047 14.3 0.0 8.4 6 2 2 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS90696.1 - 1.9e-09 37.6 19.1 0.42 11.1 0.0 9.8 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 RUS90696.1 - 2e-07 31.2 8.2 0.8 10.1 0.0 8.2 8 1 1 9 9 9 2 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS90696.1 - 5e-06 26.8 0.3 1.4e-05 25.3 0.3 1.8 1 0 0 1 1 1 1 SOCS box Ank_3 PF13606.6 RUS90696.1 - 3.1e-05 24.0 13.0 2.4 9.0 0.0 8.8 10 0 0 10 10 10 1 Ankyrin repeat Amidase PF01425.21 RUS90697.1 - 9.7e-67 225.9 0.0 8.3e-60 203.0 0.0 2.3 2 1 0 2 2 2 2 Amidase SIR2 PF02146.17 RUS90698.1 - 3.7e-25 88.9 0.3 1.1e-24 87.4 0.3 1.7 1 1 0 1 1 1 1 Sir2 family HTH_8 PF02954.19 RUS90698.1 - 0.14 12.0 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family TPR_2 PF07719.17 RUS90699.1 - 4e-39 129.6 8.0 1.6e-06 27.8 0.5 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS90699.1 - 2e-36 121.1 1.4 2.2e-06 27.4 0.1 10.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 RUS90699.1 - 3.3e-36 121.6 7.5 3.6e-08 32.9 0.5 9.8 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 RUS90699.1 - 1.1e-32 110.1 9.1 0.031 14.7 0.0 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 RUS90699.1 - 1.1e-29 100.5 16.6 0.0047 17.6 0.0 11.2 2 2 9 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.6 RUS90699.1 - 1.7e-29 102.2 19.4 2.1e-07 31.3 0.1 7.6 5 3 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS90699.1 - 3.9e-26 91.4 10.6 0.00013 22.5 0.0 7.9 2 2 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 RUS90699.1 - 2.3e-23 80.5 7.4 0.022 14.8 0.7 8.8 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 RUS90699.1 - 1.7e-22 79.5 23.7 1.2e-05 25.5 0.0 7.2 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 RUS90699.1 - 2.6e-21 75.0 12.0 1.4e-06 27.9 0.2 9.3 6 2 3 9 9 9 4 TPR repeat DUF1736 PF08409.11 RUS90699.1 - 1.3e-16 60.4 6.2 1.3e-16 60.4 6.2 2.0 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) ANAPC3 PF12895.7 RUS90699.1 - 3e-12 46.6 8.3 0.00034 20.8 0.0 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 RUS90699.1 - 4.1e-11 42.4 31.3 0.028 14.3 0.8 10.2 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS90699.1 - 1.5e-10 41.0 12.6 0.19 12.5 0.4 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 RUS90699.1 - 3.2e-09 36.8 12.0 0.0021 18.2 0.2 5.0 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 RUS90699.1 - 1.2e-08 34.7 8.8 0.22 12.3 0.0 7.7 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 RUS90699.1 - 1.6e-08 34.1 8.7 0.0047 16.2 0.0 4.6 1 1 3 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.8 RUS90699.1 - 5e-05 22.4 4.1 2.6 6.8 0.1 4.5 2 1 2 5 5 5 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 RUS90699.1 - 0.0004 19.9 1.0 0.023 14.1 0.6 2.8 2 2 2 4 4 4 1 Coatomer epsilon subunit FAT PF02259.23 RUS90699.1 - 0.00055 19.3 2.0 0.16 11.2 0.6 3.1 1 1 2 3 3 3 1 FAT domain Sel1 PF08238.12 RUS90699.1 - 0.0049 17.5 1.9 21 6.0 0.1 4.8 5 0 0 5 5 5 0 Sel1 repeat HrpB1_HrpK PF09613.10 RUS90699.1 - 0.0052 16.4 1.6 2 8.1 0.0 3.6 1 1 4 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) ChAPs PF09295.10 RUS90699.1 - 0.0073 15.4 0.0 0.9 8.5 0.0 2.8 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 RUS90699.1 - 0.014 15.4 5.2 0.83 9.7 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 RUS90699.1 - 0.32 10.4 6.7 7.9 5.8 0.9 3.6 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP TFIID-18kDa PF02269.16 RUS90700.1 - 4.8e-36 122.7 0.8 6.3e-36 122.3 0.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Suf PF05843.14 RUS90701.1 - 5.7e-77 259.6 21.2 1.9e-73 248.1 2.3 5.4 4 2 1 5 5 5 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 RUS90701.1 - 0.008 15.3 15.2 0.57 9.2 0.3 5.3 3 2 2 6 6 6 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 RUS90701.1 - 0.0085 16.8 0.1 5.7 8.0 0.0 5.0 4 2 2 6 6 6 1 Tetratricopeptide repeat SF3A3 PF16837.5 RUS90701.1 - 0.0097 16.4 6.4 0.018 15.5 1.3 3.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TPR_6 PF13174.6 RUS90701.1 - 0.031 14.9 2.7 0.21 12.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 RUS90701.1 - 0.23 11.5 3.8 1 9.4 0.0 3.8 3 1 0 3 3 3 0 HAT (Half-A-TPR) repeat Integrase_H2C2 PF17921.1 RUS90703.1 - 3.2e-08 33.6 0.0 6.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 RUS90703.1 - 0.0014 18.7 0.0 0.068 13.3 0.0 2.5 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-H2C2 PF09337.10 RUS90703.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger bZIP_1 PF00170.21 RUS90704.1 - 0.017 15.2 5.5 0.044 13.9 4.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor Tctex-1 PF03645.13 RUS90704.1 - 0.11 12.7 1.3 0.3 11.3 1.3 1.9 1 1 0 1 1 1 0 Tctex-1 family AAA_5 PF07728.14 RUS90705.1 - 7e-35 120.0 0.0 1.7e-15 57.2 0.0 3.3 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_5 PF17865.1 RUS90705.1 - 2.3e-30 104.8 0.0 8e-30 103.1 0.0 2.0 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_lid_7 PF17867.1 RUS90705.1 - 2.5e-26 91.9 0.0 9.1e-23 80.5 0.0 3.6 3 0 0 3 3 3 1 Midasin AAA lid domain AAA_7 PF12775.7 RUS90705.1 - 4.6e-11 42.6 0.3 5.5e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_6 PF12774.7 RUS90705.1 - 3.1e-10 39.5 0.2 0.004 16.2 0.2 3.3 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 RUS90705.1 - 1.8e-09 37.5 0.0 0.0092 15.8 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 RUS90705.1 - 7.4e-09 36.1 0.1 0.0037 17.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RUS90705.1 - 2.7e-08 33.8 0.1 0.0063 16.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 RUS90705.1 - 7.2e-08 33.0 3.0 0.00038 20.9 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 RUS90705.1 - 4.1e-07 30.3 1.8 0.023 15.0 0.1 3.6 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 RUS90705.1 - 1.8e-06 27.7 0.1 0.02 14.6 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain Dynein_heavy PF03028.15 RUS90705.1 - 3.6e-06 27.1 0.0 0.0045 17.1 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Sigma54_activ_2 PF14532.6 RUS90705.1 - 2.6e-05 24.4 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RUS90705.1 - 4.2e-05 23.0 0.2 0.069 12.5 0.1 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 RUS90705.1 - 4.6e-05 23.4 0.9 0.28 11.1 0.2 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain NACHT PF05729.12 RUS90705.1 - 0.00015 21.7 0.3 0.23 11.4 0.1 3.0 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 RUS90705.1 - 0.00016 22.2 0.0 0.85 10.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.13 RUS90705.1 - 0.00021 20.6 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 RUS90705.1 - 0.00022 21.0 0.0 0.62 9.8 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 RUS90705.1 - 0.00026 21.3 0.4 1.1 9.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 RUS90705.1 - 0.00026 20.1 0.2 0.24 10.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 RUS90705.1 - 0.0003 21.1 0.2 0.7 10.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_11 PF13086.6 RUS90705.1 - 0.00035 20.4 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RUS90705.1 - 0.00041 20.4 0.0 2.3 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 RUS90705.1 - 0.00046 20.0 0.1 0.59 9.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 RUS90705.1 - 0.0013 18.8 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 RUS90705.1 - 0.0028 17.3 0.8 2.4 7.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RUS90705.1 - 0.0042 16.8 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 RUS90705.1 - 0.0047 16.3 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 RUS90705.1 - 0.0075 16.8 0.1 6.1 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 RUS90705.1 - 0.019 14.9 0.2 13 5.6 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 RUS90705.1 - 0.019 14.2 0.0 0.93 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 RUS90705.1 - 0.019 15.2 0.6 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 RUS90705.1 - 0.023 14.3 0.3 2.6 7.6 0.0 3.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain DEAD PF00270.29 RUS90705.1 - 0.044 13.6 0.2 5.2 6.8 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 RUS90705.1 - 0.049 13.8 0.0 6.1 7.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 RUS90705.1 - 0.052 13.1 0.2 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 RUS90705.1 - 0.054 12.9 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Zn_ribbon_17 PF17120.5 RUS90705.1 - 0.077 12.6 2.2 4.8 6.9 0.5 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PduV-EutP PF10662.9 RUS90705.1 - 0.13 12.0 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.12 RUS90705.1 - 0.13 10.8 0.2 0.63 8.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) CbiA PF01656.23 RUS90705.1 - 0.13 12.3 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SHMT PF00464.19 RUS90705.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase dNK PF01712.19 RUS90705.1 - 0.22 11.4 0.3 4 7.2 0.0 2.7 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_5 PF07728.14 RUS90706.1 - 3e-23 82.3 0.0 5.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RUS90706.1 - 5.2e-16 58.8 0.0 9e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 RUS90706.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 RUS90706.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 RUS90706.1 - 0.0065 16.9 1.2 0.68 10.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 RUS90706.1 - 0.0083 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 RUS90706.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RUS90706.1 - 0.013 15.0 0.1 3.6 7.1 0.0 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 RUS90707.1 - 1.5e-16 60.7 0.0 2.3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_5 PF07728.14 RUS90708.1 - 3.6e-35 120.9 0.0 1e-16 61.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RUS90708.1 - 5.9e-15 55.4 0.0 3.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 RUS90708.1 - 1.7e-10 41.4 0.0 9.4e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 RUS90708.1 - 6.5e-10 39.0 0.0 3.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RUS90708.1 - 6.8e-09 36.3 0.7 0.0029 18.0 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain Dynein_heavy PF03028.15 RUS90708.1 - 2.2e-07 31.0 0.0 0.00046 20.3 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_28 PF13521.6 RUS90708.1 - 4.6e-05 23.7 1.5 0.068 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RUS90708.1 - 6.7e-05 23.2 0.1 0.032 14.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RUS90708.1 - 0.00015 22.3 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.6 RUS90708.1 - 0.00041 20.9 0.0 0.97 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_6 PF12774.7 RUS90708.1 - 0.00048 19.2 0.1 0.11 11.5 0.1 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 RUS90708.1 - 0.00068 19.2 0.0 0.29 10.6 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_25 PF13481.6 RUS90708.1 - 0.00076 19.1 0.0 0.3 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RUS90708.1 - 0.00076 19.2 0.0 0.021 14.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 RUS90708.1 - 0.0012 18.8 0.1 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RUS90708.1 - 0.0026 17.0 0.2 0.049 12.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 RUS90708.1 - 0.0033 17.5 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RUS90708.1 - 0.0038 17.4 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RUS90708.1 - 0.0061 16.5 0.2 0.1 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain CPT PF07931.12 RUS90708.1 - 0.0076 16.1 0.0 7 6.5 0.0 3.1 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_8 PF12780.7 RUS90708.1 - 0.02 14.2 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Baculo_PEP_C PF04513.12 RUS90708.1 - 0.024 14.7 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DnaB_C PF03796.15 RUS90708.1 - 0.026 13.8 0.0 1.7 7.9 0.0 2.9 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 RUS90708.1 - 0.027 13.8 0.0 0.57 9.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 RUS90708.1 - 0.03 14.1 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RUS90708.1 - 0.041 14.3 0.0 17 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 RUS90708.1 - 0.088 12.7 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 RUS90708.1 - 0.093 12.9 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 RUS90708.1 - 0.18 11.4 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 7tm_1 PF00001.21 RUS90709.1 - 6.5e-09 35.5 12.0 1.5e-08 34.3 1.6 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Mito_fiss_reg PF05308.11 RUS90709.1 - 0.058 13.5 1.5 0.089 12.9 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator VWA_2 PF13519.6 RUS90710.1 - 8.7e-07 29.6 0.6 3.1e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RUS90710.1 - 8.8e-05 22.8 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain 7tm_1 PF00001.21 RUS90711.1 - 3e-14 53.0 7.0 4.1e-14 52.5 7.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS90711.1 - 3.4e-05 23.3 0.3 3.4e-05 23.3 0.3 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS90711.1 - 0.00022 20.9 2.2 0.00022 20.9 2.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 RUS90711.1 - 0.003 17.0 1.5 0.003 17.0 1.5 2.6 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 RUS90711.1 - 0.79 9.0 8.6 5.1 6.4 2.0 2.8 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF908 PF06012.12 RUS90713.1 - 0.19 11.1 4.8 0.22 10.9 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 RUS90713.1 - 0.55 8.9 2.2 0.62 8.8 2.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 RUS90713.1 - 0.91 8.0 7.5 1 7.8 7.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 RUS90713.1 - 1.3 7.8 8.6 1.5 7.5 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain QWRF PF04484.12 RUS90713.1 - 4.3 7.0 12.4 5.2 6.7 12.4 1.1 1 0 0 1 1 1 0 QWRF family Peroxin-3 PF04882.12 RUS90713.1 - 6.2 5.7 8.9 7.9 5.3 8.9 1.1 1 0 0 1 1 1 0 Peroxin-3 TMEM135_C_rich PF15982.5 RUS90714.1 - 2.1e-32 112.5 2.4 2.3e-32 112.4 2.4 1.0 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 SPO22 PF08631.10 RUS90716.1 - 8.8e-46 156.6 21.5 1e-45 156.4 4.5 3.1 4 0 0 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 RUS90716.1 - 5.3e-11 41.8 5.9 0.021 14.9 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS90716.1 - 2.9e-10 40.3 6.1 0.0025 18.1 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS90716.1 - 2.4e-08 34.4 4.8 0.002 18.6 0.1 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS90716.1 - 1.3e-07 31.1 9.5 0.0066 16.2 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS90716.1 - 0.00091 19.8 5.3 0.038 14.6 0.0 4.6 5 1 1 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS90716.1 - 0.002 18.3 0.6 0.002 18.3 0.6 5.9 5 2 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RUS90716.1 - 0.0038 16.9 6.7 2.3 8.0 0.0 4.6 5 0 0 5 5 5 2 TPR repeat TPR_14 PF13428.6 RUS90716.1 - 0.0045 17.7 1.6 58 4.9 0.0 5.5 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS90716.1 - 0.0054 16.8 8.9 4.3 7.8 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat YfiO PF13525.6 RUS90716.1 - 0.036 13.8 0.5 0.53 10.0 0.2 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_17 PF13431.6 RUS90716.1 - 0.052 13.9 0.6 2.1 8.9 0.3 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS90716.1 - 0.08 13.6 0.8 11 6.9 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 RUS90716.1 - 0.26 11.3 3.6 4 7.5 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS90716.1 - 0.4 10.8 6.7 2.5 8.3 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat WWE PF02825.20 RUS90717.1 - 3.5e-10 40.3 1.4 0.0001 22.8 0.1 2.7 1 1 1 2 2 2 2 WWE domain Peptidase_C15 PF01470.17 RUS90718.1 - 1.5e-16 61.2 0.0 2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 RUS90718.1 - 2.4e-05 24.1 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 PhoLip_ATPase_C PF16212.5 RUS90719.1 - 8.6e-82 274.6 25.0 8.6e-82 274.6 25.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RUS90719.1 - 1.8e-26 91.6 3.6 5.1e-26 90.2 3.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RUS90719.1 - 1.3e-10 42.0 0.8 6.5e-05 23.3 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RUS90719.1 - 8.1e-10 38.7 0.0 4.1e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RUS90719.1 - 2.1e-05 24.2 1.4 4.1e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RUS90719.1 - 0.0022 17.8 0.1 0.0061 16.3 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4166 PF13761.6 RUS90719.1 - 0.15 11.8 0.2 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) Pox_Ag35 PF03286.14 RUS90720.1 - 0.024 14.4 46.3 0.13 12.0 18.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MDM10 PF12519.8 RUS90720.1 - 0.28 10.0 22.0 0.39 9.5 22.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CobT PF06213.12 RUS90720.1 - 0.42 10.0 64.2 1.5 8.1 30.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 RUS90720.1 - 0.55 9.2 72.5 1.5 7.7 29.2 2.1 2 0 0 2 2 2 0 Paf1 Connexin PF00029.19 RUS90720.1 - 0.7 9.6 30.9 0.52 10.0 10.1 2.1 2 0 0 2 2 2 0 Connexin RNA_polI_A34 PF08208.11 RUS90720.1 - 0.75 9.9 46.9 0.77 9.8 19.2 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 RUS90720.1 - 0.89 8.3 26.1 1.2 7.8 26.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFB6 PF17110.5 RUS90720.1 - 1.3 8.7 38.8 1 9.1 15.1 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Nop25 PF09805.9 RUS90720.1 - 5.5 7.5 59.4 5.2 7.5 29.9 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nop53 PF07767.11 RUS90720.1 - 7.8 5.8 63.5 4.5 6.6 28.2 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) WD40 PF00400.32 RUS90721.1 - 2.2e-08 34.6 11.0 0.031 15.2 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat SPRY PF00622.28 RUS90725.1 - 5.4e-13 49.1 0.7 3e-12 46.7 0.7 2.1 1 1 0 1 1 1 1 SPRY domain PHD PF00628.29 RUS90725.1 - 2e-06 27.6 4.2 3.8e-06 26.7 4.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-CCHC_3 PF13917.6 RUS90725.1 - 0.057 13.4 1.1 0.14 12.1 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4850 PF16142.5 RUS90725.1 - 0.092 12.2 0.1 0.71 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4850) C1_1 PF00130.22 RUS90725.1 - 6.1 6.8 7.0 0.55 10.2 1.7 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF2A PF08662.11 RUS90727.1 - 1.5e-60 204.4 2.1 1.2e-53 181.9 1.1 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 RUS90727.1 - 1.7e-09 37.4 0.1 4.5e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 RUS90727.1 - 0.01 16.6 1.0 78 4.4 0.1 5.0 6 0 0 6 6 6 0 WD domain, G-beta repeat Methyltr_RsmF_N PF17125.5 RUS90727.1 - 0.019 15.5 0.1 0.88 10.1 0.0 2.9 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Nefa_Nip30_N PF10187.9 RUS90727.1 - 3.5 8.0 17.0 0.23 11.9 10.0 2.6 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Mito_carr PF00153.27 RUS90728.1 - 6.9e-61 202.2 1.0 2e-20 72.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 RUS90729.1 - 8.4e-74 248.3 0.0 9.6e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90729.1 - 2.2e-33 115.7 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS90729.1 - 3.1e-05 23.1 0.0 7.3e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS90729.1 - 0.014 15.3 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 RUS90729.1 - 0.13 11.6 0.1 0.36 10.2 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 RUS90730.1 - 9.3e-11 41.4 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.11 RUS90731.1 - 1.2e-182 608.4 0.0 2.8e-173 577.5 0.0 2.0 2 0 0 2 2 2 2 SGT1 protein Flagellin_C PF00700.21 RUS90731.1 - 0.19 12.1 0.1 0.47 10.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Acetyltransf_3 PF13302.7 RUS90732.1 - 9.5e-22 78.2 0.0 1.2e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RUS90732.1 - 6.9e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 RUS90732.1 - 5.6e-06 26.1 0.1 2.9e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RUS90732.1 - 9.9e-06 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RUS90732.1 - 0.0038 17.6 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RUS90732.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RUS90732.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRP7 PF12923.7 RUS90733.1 - 4.7e-29 100.9 22.6 8.2e-29 100.2 22.6 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 RUS90733.1 - 1e-06 28.4 0.0 6.3e-05 22.7 0.0 3.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 RUS90733.1 - 0.00022 21.1 0.9 0.0007 19.4 0.0 2.2 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 RUS90733.1 - 0.0028 17.6 0.0 0.0074 16.3 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MG1 PF17790.1 RUS90733.1 - 1.3 9.5 3.8 5.6 7.5 0.3 2.7 2 0 0 2 2 2 0 Macroglobulin domain MG1 DUF4507 PF14964.6 RUS90734.1 - 9.7e-63 212.2 0.1 1.2e-62 211.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Ank PF00023.30 RUS90735.1 - 9.2e-86 278.9 26.9 4.9e-08 33.1 0.0 14.1 14 0 0 14 14 14 13 Ankyrin repeat Ank_2 PF12796.7 RUS90735.1 - 6.1e-81 267.1 22.3 9.8e-16 58.1 0.3 7.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS90735.1 - 4.4e-80 262.7 37.1 6.3e-12 45.5 0.2 11.4 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS90735.1 - 2.3e-72 238.5 16.6 2.1e-09 37.7 0.1 12.3 2 2 11 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS90735.1 - 2.2e-70 224.2 11.5 0.00014 22.0 0.0 14.1 14 0 0 14 14 14 12 Ankyrin repeat PTS_IIA PF02255.16 RUS90735.1 - 0.009 16.0 4.0 3.8 7.6 0.3 4.3 4 0 0 4 4 4 1 PTS system, Lactose/Cellobiose specific IIA subunit DUF249 PF03158.13 RUS90735.1 - 0.011 15.5 0.3 5.2 6.7 0.1 3.3 3 2 1 4 4 4 0 Multigene family 530 protein Nepo_coat_C PF03688.14 RUS90735.1 - 0.022 14.6 0.1 0.37 10.6 0.0 2.6 2 1 0 2 2 2 0 Nepovirus coat protein, C-terminal domain DUF4926 PF16277.5 RUS90735.1 - 0.073 12.5 0.0 0.5 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) Lpp-LpqN PF10738.9 RUS90735.1 - 0.075 12.5 0.4 1 8.8 0.0 2.4 3 0 0 3 3 3 0 Probable lipoprotein LpqN RNA_pol_Rpb1_4 PF05000.17 RUS90735.1 - 0.1 12.6 0.3 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 Shigella_OspC PF06128.11 RUS90735.1 - 0.11 12.2 3.5 5.1 6.7 0.3 3.7 4 0 0 4 4 4 0 Shigella flexneri OspC protein Pollen_allerg_1 PF01357.21 RUS90735.1 - 0.18 11.9 0.2 14 5.8 0.1 3.2 2 2 1 3 3 3 0 Pollen allergen Lectin_C PF00059.21 RUS90736.1 - 1.2e-10 42.0 7.4 1.2e-05 26.0 0.0 4.4 4 0 0 4 4 4 3 Lectin C-type domain IgGFc_binding PF17517.2 RUS90736.1 - 2.8e-05 23.5 2.8 2.8e-05 23.5 2.8 2.2 2 1 1 3 3 3 1 IgGFc binding protein PPP4R2 PF09184.11 RUS90736.1 - 0.72 9.4 16.4 1.1 8.8 16.4 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 RUS90736.1 - 1 9.3 18.7 1.5 8.7 18.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 RUS90736.1 - 1.8 7.6 14.1 3 6.9 14.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 RUS90736.1 - 2.3 7.5 32.8 4.8 6.4 32.8 1.5 1 0 0 1 1 1 0 NOA36 protein Keratin_B2 PF01500.17 RUS90737.1 - 0.012 15.6 34.5 1.4 8.8 11.2 3.6 1 1 2 3 3 3 0 Keratin, high sulfur B2 protein Cornifin PF02389.15 RUS90740.1 - 0.0071 16.5 5.2 0.0093 16.2 5.2 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family GETHR PF05671.11 RUS90740.1 - 0.013 14.9 32.4 2.2e+03 -1.8 0.1 6.7 2 1 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) Amelotin PF15757.5 RUS90740.1 - 0.37 10.4 8.6 0.68 9.5 3.4 2.3 1 1 1 2 2 2 0 Amelotin Raftlin PF15250.6 RUS90740.1 - 0.74 8.5 4.0 0.75 8.5 4.0 1.0 1 0 0 1 1 1 0 Raftlin TGS PF02824.21 RUS90740.1 - 1.3 9.1 7.3 36 4.5 0.2 3.8 2 1 2 4 4 4 0 TGS domain ABC_tran PF00005.27 RUS90741.1 - 5.4e-07 30.2 0.0 8.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS90741.1 - 2.6e-05 24.2 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RUS90742.1 - 1.6e-15 57.1 10.9 1.8e-15 56.9 10.9 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein HLH PF00010.26 RUS90743.1 - 5.3e-17 61.5 0.1 8.6e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 RUS90743.1 - 0.0087 15.7 0.2 0.04 13.6 0.0 2.0 2 0 0 2 2 2 1 Transcription factor COE1 helix-loop-helix domain Malic_M PF03949.15 RUS90744.1 - 2.7e-94 315.2 0.0 3.4e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 RUS90744.1 - 2.7e-79 265.2 0.0 4.1e-79 264.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RRM_1 PF00076.22 RUS90745.1 - 1.2e-14 53.8 0.2 2.2e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS90745.1 - 0.0042 17.2 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif DUF3391 PF11871.8 RUS90745.1 - 0.44 11.1 5.8 0.66 10.5 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4078 PF13300.6 RUS90746.1 - 9.1e-24 83.6 10.7 9.1e-24 83.6 10.7 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4078) Tctex-1 PF03645.13 RUS90748.1 - 4.8e-35 119.9 0.3 5.4e-35 119.7 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family PTP2 PF17022.5 RUS90748.1 - 0.014 15.0 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia RNase_J_C PF17770.1 RUS90748.1 - 0.12 13.4 0.0 0.15 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain Sec63 PF02889.16 RUS90749.1 - 5.2e-146 484.6 0.1 1.5e-85 286.5 1.3 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RUS90749.1 - 3.4e-53 180.0 0.7 7.9e-27 94.1 1.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 RUS90749.1 - 1.3e-24 87.2 0.1 7.8e-12 45.5 0.2 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RUS90749.1 - 5.1e-18 65.4 0.1 3.7e-08 33.7 0.0 3.8 3 2 0 3 3 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 RUS90749.1 - 3.3e-08 33.9 3.1 0.00035 20.9 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 RUS90749.1 - 1.1e-05 25.2 0.2 0.018 14.8 0.2 3.1 2 1 1 3 3 3 2 AAA domain T2SSE PF00437.20 RUS90749.1 - 0.0015 17.7 0.0 0.62 9.1 0.1 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 RUS90749.1 - 0.002 18.5 1.7 0.16 12.3 1.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 RUS90749.1 - 0.0076 15.9 0.0 0.027 14.1 0.0 1.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 RUS90749.1 - 0.009 15.7 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 RUS90749.1 - 0.011 15.2 0.0 2.2 7.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 RUS90749.1 - 0.032 13.7 0.2 3.8 6.9 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 RUS90749.1 - 0.06 13.1 1.5 0.59 9.8 0.0 3.1 4 0 0 4 4 4 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 RUS90749.1 - 0.17 11.4 0.4 1.4 8.4 0.3 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Spectrin PF00435.21 RUS90750.1 - 0.0028 18.1 1.3 0.0039 17.7 1.3 1.2 1 0 0 1 1 1 1 Spectrin repeat Syndecan PF01034.20 RUS90751.1 - 0.039 13.9 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF2970 PF11174.8 RUS90751.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Gal_Lectin PF02140.18 RUS90752.1 - 2.1e-05 24.8 1.2 2.8e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 Galactose binding lectin domain CUB PF00431.20 RUS90752.1 - 0.00036 20.9 0.7 0.00057 20.2 0.7 1.3 1 0 0 1 1 1 1 CUB domain Dicty_REP PF05086.12 RUS90753.1 - 0.028 12.4 0.7 0.035 12.1 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OSTbeta PF15048.6 RUS90753.1 - 0.16 12.2 0.8 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Fungus-induced PF10917.8 RUS90755.1 - 5.5 7.4 7.4 7.7 6.9 2.2 2.3 2 0 0 2 2 2 0 Fungus-induced protein OTU PF02338.19 RUS90757.1 - 4.8e-15 56.2 0.0 1.3e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.16 RUS90757.1 - 0.0048 16.8 49.1 0.01 15.8 2.4 5.2 5 0 0 5 5 5 4 A20-like zinc finger Tub PF01167.18 RUS90758.1 - 2.4e-91 305.8 2.9 3.3e-90 302.1 0.0 2.2 2 0 0 2 2 2 1 Tub family Tub_N PF16322.5 RUS90758.1 - 0.052 14.0 21.0 1.1 9.7 21.1 2.5 1 1 0 1 1 1 0 Tubby N-terminal Tau95 PF09734.9 RUS90758.1 - 1.8 9.4 9.9 2.1 9.2 1.8 2.6 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DNA_pol_B PF00136.21 RUS90759.1 - 1.6e-97 327.2 0.0 5.7e-97 325.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RUS90759.1 - 9.5e-24 84.2 0.0 3.9e-11 42.7 0.0 3.4 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 RUS90759.1 - 9.3e-14 51.7 7.0 4.3e-13 49.5 7.0 2.3 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta NHL PF01436.21 RUS90760.1 - 5.4e-10 38.8 2.9 6.3e-05 22.8 0.1 4.0 4 0 0 4 4 4 2 NHL repeat DUF2671 PF10877.8 RUS90760.1 - 0.0044 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2671) DUF5128 PF17170.4 RUS90760.1 - 0.045 12.9 0.4 2.9 7.0 0.0 2.1 1 1 1 2 2 2 0 6-bladed beta-propeller ADH_zinc_N PF00107.26 RUS90761.1 - 5.5e-23 81.4 0.2 9e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RUS90761.1 - 3.1e-18 67.1 0.0 6.7e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS90761.1 - 7e-08 32.3 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS90761.1 - 0.0012 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Phosphodiest PF01663.22 RUS90762.1 - 8.7e-71 239.4 4.7 1e-70 239.1 4.7 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS90762.1 - 5.3e-06 26.0 0.0 0.00065 19.2 0.0 2.6 1 1 1 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 RUS90762.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily SusD_RagB PF07980.11 RUS90762.1 - 0.14 11.8 1.1 0.32 10.5 1.1 1.7 1 1 0 1 1 1 0 SusD family Phosphodiest PF01663.22 RUS90763.1 - 9.2e-70 236.0 2.8 1.1e-69 235.8 2.8 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RUS90763.1 - 1e-10 41.5 0.0 1.9e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RUS90763.1 - 8.9e-05 22.0 0.0 0.00013 21.5 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily ADK PF00406.22 RUS90764.1 - 2.7e-46 157.4 7.1 4.5e-18 65.8 0.0 6.4 6 0 0 6 6 6 3 Adenylate kinase AAA_17 PF13207.6 RUS90764.1 - 2.2e-30 105.8 32.3 2.7e-09 37.6 0.0 8.6 7 1 1 8 8 7 5 AAA domain FAP206 PF12018.8 RUS90764.1 - 7.9e-14 51.8 8.5 0.012 15.2 0.0 6.3 6 0 0 6 6 6 4 Domain of unknown function AAA_18 PF13238.6 RUS90764.1 - 1e-11 45.5 21.5 0.0044 17.6 0.0 7.0 7 1 0 7 7 5 4 AAA domain AAA_33 PF13671.6 RUS90764.1 - 4.9e-11 43.0 14.1 0.0039 17.4 0.0 6.1 7 0 0 7 7 4 3 AAA domain AAA_24 PF13479.6 RUS90764.1 - 1.5e-09 37.8 0.2 0.0051 16.5 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 RUS90764.1 - 1.8e-09 38.0 0.4 0.028 14.7 0.0 5.2 5 0 0 5 5 4 2 AAA domain YHS PF04945.13 RUS90764.1 - 1.3e-08 34.8 4.6 0.14 12.3 0.0 5.5 5 0 0 5 5 5 1 YHS domain RNA_helicase PF00910.22 RUS90764.1 - 1.1e-06 29.0 0.1 1.6 9.2 0.0 5.4 5 0 0 5 5 5 2 RNA helicase AAA PF00004.29 RUS90764.1 - 1.9e-06 28.4 17.5 0.01 16.2 0.0 5.6 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 RUS90764.1 - 6.1e-06 26.5 3.1 0.18 12.0 0.0 4.4 5 0 0 5 5 4 2 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 RUS90764.1 - 1.1e-05 25.4 4.2 4.9 7.2 0.0 5.6 5 0 0 5 5 4 1 AAA domain TniB PF05621.11 RUS90764.1 - 2.3e-05 23.9 0.0 0.12 11.8 0.0 3.0 3 0 0 3 3 3 2 Bacterial TniB protein AAA_5 PF07728.14 RUS90764.1 - 3.3e-05 23.9 0.9 0.25 11.3 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RUS90764.1 - 0.00012 21.9 0.0 0.92 9.2 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 RUS90764.1 - 0.00014 22.0 0.0 8.4 6.5 0.0 4.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase NACHT PF05729.12 RUS90764.1 - 0.00014 21.8 7.5 0.005 16.8 0.0 4.3 6 0 0 6 6 4 1 NACHT domain AAA_28 PF13521.6 RUS90764.1 - 0.00029 21.1 0.0 0.00029 21.1 0.0 6.8 8 0 0 8 8 5 3 AAA domain KTI12 PF08433.10 RUS90764.1 - 0.0096 15.4 0.4 9.3 5.6 0.0 3.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 RUS90764.1 - 0.012 14.9 0.2 9.9 5.5 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RUS90764.1 - 0.013 15.9 0.0 0.013 15.9 0.0 7.9 6 2 1 7 7 6 0 AAA ATPase domain TsaE PF02367.17 RUS90764.1 - 0.018 15.1 0.0 8.2 6.5 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RUS90764.1 - 0.03 14.0 0.0 2.9 7.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein PduV-EutP PF10662.9 RUS90764.1 - 0.057 13.2 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 RUS90764.1 - 0.086 12.4 0.0 7.2 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 RUS90764.1 - 0.087 12.6 0.2 1.5e+02 2.2 0.0 4.3 5 0 0 5 5 4 0 P-loop containing region of AAA domain SKI PF01202.22 RUS90764.1 - 0.56 10.3 25.9 1.2 9.2 0.0 6.5 6 1 0 6 6 5 0 Shikimate kinase Hydin_ADK PF17213.3 RUS90764.1 - 0.74 10.1 0.0 0.74 10.1 0.0 7.2 6 1 0 6 6 5 0 Hydin Adenylate kinase-like domain HgmA PF04209.13 RUS90766.1 - 5e-219 727.2 0.4 5.7e-219 727.0 0.4 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase zf_Hakai PF18408.1 RUS90767.1 - 0.0024 17.5 0.3 0.005 16.5 0.3 1.6 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain Tmemb_55A PF09788.9 RUS90767.1 - 0.065 12.3 0.1 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A ANF_receptor PF01094.28 RUS90768.1 - 3.6e-43 148.0 0.5 4.6e-41 141.1 0.2 2.6 2 1 0 2 2 2 1 Receptor family ligand binding region Lig_chan PF00060.26 RUS90768.1 - 5.4e-37 126.9 0.0 9.2e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS90768.1 - 1.7e-30 105.6 0.0 3.5e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS90768.1 - 3.6e-21 75.6 0.0 2e-20 73.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 RUS90768.1 - 1.7e-16 59.9 0.9 4.5e-16 58.6 0.9 1.8 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.6 RUS90768.1 - 0.00029 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.16 RUS90768.1 - 0.015 15.2 0.6 0.047 13.6 0.6 1.9 1 1 0 1 1 1 0 Ion channel DUF4179 PF13786.6 RUS90768.1 - 0.14 12.6 0.1 0.48 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) RNA_pol_Rpb1_1 PF04997.12 RUS90769.1 - 0.035 13.4 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 TTL PF03133.15 RUS90770.1 - 1.9e-57 194.7 0.3 3.1e-57 194.0 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ANF_receptor PF01094.28 RUS90771.1 - 4.4e-37 128.0 0.0 1.2e-27 97.0 0.0 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region Lig_chan PF00060.26 RUS90771.1 - 1.1e-36 125.9 0.0 1.9e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 RUS90771.1 - 5.1e-28 97.6 0.0 1.1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 RUS90771.1 - 3e-19 69.3 0.0 1.2e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 RUS90771.1 - 2e-15 56.5 0.6 3.8e-15 55.6 0.6 1.5 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.6 RUS90771.1 - 4e-09 36.6 0.0 9.1e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Ion_trans_2 PF07885.16 RUS90771.1 - 0.024 14.6 0.8 0.069 13.1 0.8 1.8 1 0 0 1 1 1 0 Ion channel DUF2390 PF09523.10 RUS90771.1 - 0.16 12.3 0.4 0.33 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DSPc PF00782.20 RUS90772.1 - 1.8e-36 124.9 0.0 2.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS90772.1 - 0.0053 16.3 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RUS90773.1 - 3.9e-28 97.9 0.0 6.2e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RUS90773.1 - 0.00023 20.8 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 RUS90773.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 RUS90773.1 - 0.058 13.5 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_transf_7N PF13733.6 RUS90774.1 - 8.8e-51 171.0 0.0 1.4e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS90774.1 - 9.3e-31 105.3 0.2 1.8e-30 104.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Sec61_beta PF03911.16 RUS90774.1 - 0.11 12.6 1.2 0.18 11.9 1.2 1.3 1 0 0 1 1 1 0 Sec61beta family AMP-binding PF00501.28 RUS90777.1 - 2.4e-21 75.8 0.0 5e-13 48.4 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 RUS90777.1 - 0.0018 19.2 0.0 0.0037 18.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 RUS90777.1 - 0.21 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter OTCace PF00185.24 RUS90778.1 - 3.3e-54 183.2 0.0 1.2e-53 181.4 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 RUS90778.1 - 8.6e-37 126.4 0.0 1.3e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain LRR_8 PF13855.6 RUS90781.1 - 2.2e-37 126.6 10.8 9.7e-15 54.1 0.2 4.4 1 1 3 4 4 4 4 Leucine rich repeat 7tm_1 PF00001.21 RUS90781.1 - 1.4e-25 90.2 7.0 2.1e-25 89.5 7.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 RUS90781.1 - 2.2e-17 63.2 0.1 6.6e-10 39.0 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 RUS90781.1 - 5.9e-12 45.6 16.8 0.0026 18.1 0.1 5.6 2 1 1 5 5 5 4 Leucine Rich repeats (2 copies) Ldl_recept_a PF00057.18 RUS90781.1 - 2.6e-09 37.1 6.4 9.7e-09 35.3 6.4 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LRR_9 PF14580.6 RUS90781.1 - 3.7e-08 33.1 0.7 0.00036 20.1 0.3 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRRNT PF01462.18 RUS90781.1 - 0.037 13.7 0.7 0.037 13.7 0.7 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 RUS90781.1 - 3.8 8.4 11.1 11 7.0 0.0 6.1 7 1 0 7 7 7 0 Leucine Rich Repeat SpoIIIAH PF12685.7 RUS90782.1 - 4.9e-05 23.3 1.5 5.2e-05 23.2 1.5 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 RUS90782.1 - 8e-05 23.1 2.7 0.00012 22.5 2.7 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Nop14 PF04147.12 RUS90782.1 - 0.00032 19.1 24.2 0.00039 18.8 24.2 1.0 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 RUS90782.1 - 0.00093 18.1 0.5 0.00096 18.1 0.5 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.13 RUS90782.1 - 0.0014 18.9 8.5 0.0016 18.8 8.5 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated Zip PF02535.22 RUS90782.1 - 0.0038 16.5 1.1 0.0045 16.2 1.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF5427 PF10310.9 RUS90782.1 - 0.0066 15.5 14.1 0.0089 15.0 14.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Coilin_N PF15862.5 RUS90782.1 - 0.0076 16.1 3.2 0.011 15.6 3.2 1.2 1 0 0 1 1 1 1 Coilin N-terminus SDA1 PF05285.12 RUS90782.1 - 0.0079 15.7 28.0 0.01 15.3 28.0 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 RUS90782.1 - 0.0088 15.4 19.9 0.011 15.1 19.9 1.1 1 0 0 1 1 1 1 BUD22 AAA_11 PF13086.6 RUS90782.1 - 0.01 15.6 0.6 0.01 15.6 0.6 1.2 1 0 0 1 1 1 0 AAA domain SpoIIP PF07454.11 RUS90782.1 - 0.014 14.9 11.2 0.019 14.5 11.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 RUS90782.1 - 0.015 15.5 0.3 0.02 15.1 0.3 1.2 1 0 0 1 1 1 0 DDHD domain IFT57 PF10498.9 RUS90782.1 - 0.035 13.1 13.1 0.044 12.7 13.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CPSF100_C PF13299.6 RUS90782.1 - 0.04 14.1 9.4 0.059 13.6 9.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 RUS90782.1 - 0.045 12.7 0.3 0.044 12.7 0.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mpp10 PF04006.12 RUS90782.1 - 0.047 12.1 29.7 0.061 11.8 29.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SID-1_RNA_chan PF13965.6 RUS90782.1 - 0.1 11.0 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5308 PF17233.2 RUS90782.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF5523 PF17661.1 RUS90782.1 - 0.12 12.0 32.7 0.17 11.5 32.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF913 PF06025.12 RUS90782.1 - 0.13 11.2 7.7 0.16 10.9 7.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dynamin_N PF00350.23 RUS90782.1 - 0.18 11.8 0.4 0.2 11.7 0.4 1.2 1 0 0 1 1 1 0 Dynamin family PIP5K PF01504.18 RUS90782.1 - 0.18 11.0 1.0 0.22 10.7 1.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Tim54 PF11711.8 RUS90782.1 - 0.23 10.2 18.4 0.31 9.8 18.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 RUS90782.1 - 0.48 9.2 10.6 0.62 8.8 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BORG_CEP PF14957.6 RUS90782.1 - 0.5 11.5 5.0 0.22 12.7 2.3 1.7 2 0 0 2 2 1 0 Cdc42 effector Connexin PF00029.19 RUS90782.1 - 0.53 10.0 11.4 0.79 9.4 11.4 1.2 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 RUS90782.1 - 0.63 8.3 25.5 0.86 7.8 25.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 RUS90782.1 - 0.71 9.6 23.2 0.98 9.2 23.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 RUS90782.1 - 1 9.7 17.9 1.6 9.1 17.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PI3K_1B_p101 PF10486.9 RUS90782.1 - 1.4 6.7 11.1 2.3 5.9 11.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 RUS90782.1 - 1.4 7.6 13.7 2 7.1 13.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 RUS90782.1 - 1.7 7.1 10.7 2.1 6.9 10.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DNA_pol_phi PF04931.13 RUS90782.1 - 1.9 6.5 40.6 2.4 6.1 40.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pet20 PF08692.10 RUS90782.1 - 3.3 8.4 5.8 5.5 7.7 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 RAB3GAP2_C PF14656.6 RUS90782.1 - 3.7 5.7 8.3 4.7 5.3 8.3 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RNA_polI_A34 PF08208.11 RUS90782.1 - 3.8 7.5 25.4 6 6.9 25.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EIIBC-GUT_N PF03612.14 RUS90782.1 - 4.2 7.1 11.4 7.3 6.3 11.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pox_Ag35 PF03286.14 RUS90782.1 - 4.3 7.1 23.5 8.5 6.1 23.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SLC12 PF03522.15 RUS90782.1 - 4.6 6.2 9.2 6.1 5.7 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 RUS90782.1 - 6.4 5.8 13.2 8.6 5.3 13.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4471 PF14740.6 RUS90782.1 - 7.6 5.6 10.1 11 5.2 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) PTPRCAP PF15713.5 RUS90782.1 - 9 6.6 31.5 17 5.7 31.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4637 PF15470.6 RUS90782.1 - 9.1 6.0 33.6 15 5.2 33.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Smg8_Smg9 PF10220.9 RUS90782.1 - 9.2 4.4 8.0 11 4.1 8.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 BSMAP PF12280.8 RUS90782.1 - 9.9 6.3 7.9 22 5.2 4.9 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein NARP1 PF12569.8 RUS90784.1 - 0.26 10.1 4.7 0.34 9.8 4.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med19 PF10278.9 RUS90784.1 - 1.3 9.0 11.4 1.9 8.4 11.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4174 PF13778.6 RUS90785.1 - 0.0033 17.9 0.5 0.0053 17.2 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) CEP76-C2 PF15627.6 RUS90786.1 - 7.7e-53 178.3 0.0 1.6e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 RUS90786.1 - 0.0011 19.4 0.1 0.0026 18.2 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 RUS90786.1 - 0.0044 16.9 0.4 0.0082 16.0 0.4 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily PolyA_pol_arg_C PF12626.7 RUS90786.1 - 0.45 10.6 3.8 0.45 10.6 0.3 2.4 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus RVT_1 PF00078.27 RUS90787.1 - 5.2e-13 49.0 0.0 8.5e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.12 RUS90787.1 - 0.049 11.9 20.9 0.061 11.5 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 RUS90787.1 - 0.13 11.9 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 RUS90787.1 - 0.5 8.6 15.0 0.75 8.0 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.9 RUS90787.1 - 2.6 8.5 6.6 3.8 8.0 6.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CobT PF06213.12 RUS90787.1 - 3.3 7.0 17.3 4.9 6.5 17.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LRR_4 PF12799.7 RUS90788.1 - 1.2e-07 31.9 5.0 0.012 16.0 1.5 3.1 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS90788.1 - 1.1e-05 25.1 4.5 0.0039 16.9 0.9 2.6 2 0 0 2 2 2 2 Leucine rich repeat PH PF00169.29 RUS90788.1 - 0.00055 20.4 0.1 0.0018 18.8 0.1 1.8 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.6 RUS90788.1 - 0.0006 19.7 2.9 1.1 9.5 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat DEAD PF00270.29 RUS90789.1 - 4.2e-47 160.2 0.2 8.6e-47 159.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS90789.1 - 5.4e-31 107.2 0.6 1.8e-28 99.1 0.2 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 RUS90789.1 - 4.3e-07 29.1 3.1 0.0022 16.8 0.0 3.3 2 1 1 3 3 3 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3802 PF12290.8 RUS90789.1 - 0.045 14.2 0.9 0.15 12.6 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) AAA_22 PF13401.6 RUS90789.1 - 0.054 13.8 1.7 0.35 11.1 1.7 2.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 RUS90789.1 - 0.32 10.7 0.0 0.32 10.7 0.0 3.0 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family GTP1_OBG PF01018.22 RUS90790.1 - 8.4e-47 158.6 6.6 1.4e-46 157.9 6.6 1.4 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 RUS90790.1 - 1.1e-20 73.8 0.0 4.7e-20 71.8 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RUS90790.1 - 2.9e-08 33.4 0.0 1.5e-07 31.1 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 RUS90790.1 - 0.0013 19.3 0.0 0.037 14.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Arf PF00025.21 RUS90790.1 - 0.0026 17.2 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS90790.1 - 0.0044 16.6 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 RUS90790.1 - 0.0056 15.7 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TMEM189_B_dmain PF10520.9 RUS90791.1 - 2.4e-75 252.4 1.8 3.7e-75 251.8 1.8 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain OPT PF03169.15 RUS90791.1 - 0.007 15.0 1.2 0.0073 15.0 0.0 1.5 2 0 0 2 2 2 1 OPT oligopeptide transporter protein Pox_MCEL PF03291.16 RUS90792.1 - 2.3e-101 339.3 0.2 2.8e-101 339.0 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 RUS90792.1 - 2.1e-12 47.6 0.0 4e-11 43.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS90792.1 - 3.3e-08 34.1 0.0 1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS90792.1 - 2e-07 30.9 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS90792.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS90792.1 - 0.00013 22.6 0.0 0.00056 20.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain NIF3 PF01784.18 RUS90792.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) NNMT_PNMT_TEMT PF01234.17 RUS90792.1 - 0.083 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF5347 PF17282.2 RUS90792.1 - 0.17 12.2 0.6 8.8 6.7 0.1 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5347) PAP_PilO PF06864.12 RUS90793.1 - 0.006 15.5 0.0 0.0068 15.3 0.0 1.1 1 0 0 1 1 1 1 Pilin accessory protein (PilO) KASH_CCD PF14662.6 RUS90794.1 - 0.00038 20.3 20.8 0.00038 20.3 20.8 7.5 2 2 6 8 8 8 3 Coiled-coil region of CCDC155 or KASH Takusan PF04822.13 RUS90794.1 - 0.0011 18.9 5.0 0.0011 18.9 5.0 9.1 7 2 3 10 10 10 3 Takusan CENP-F_leu_zip PF10473.9 RUS90794.1 - 0.0051 16.9 159.5 0.13 12.3 25.1 10.3 2 2 8 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 RUS90794.1 - 0.0082 15.8 24.2 0.0082 15.8 24.2 8.1 2 2 6 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 RUS90794.1 - 0.36 11.0 166.6 0.51 10.5 12.7 9.5 2 2 7 9 9 9 0 Autophagy protein 16 (ATG16) ERM PF00769.19 RUS90794.1 - 2.9 7.6 160.7 0.14 11.9 19.1 7.6 2 2 4 6 6 6 0 Ezrin/radixin/moesin family Cadherin PF00028.17 RUS90796.1 - 3.1e-82 271.1 1.0 3.7e-18 65.7 0.1 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 RUS90796.1 - 1.5e-08 34.4 0.3 5 7.0 0.1 6.8 5 2 0 5 5 5 2 Cadherin-like Y_Y_Y PF07495.13 RUS90796.1 - 0.0029 17.5 0.0 19 5.3 0.0 4.4 5 0 0 5 5 5 2 Y_Y_Y domain Adeno_E3_CR2 PF02439.15 RUS90796.1 - 0.014 15.2 1.3 0.025 14.3 1.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 RUS90796.1 - 0.18 12.7 1.1 0.52 11.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin PF00028.17 RUS90797.1 - 6.8e-21 74.5 2.1 2.4e-12 47.1 0.1 2.6 3 1 0 3 3 3 2 Cadherin domain Cadherin_2 PF08266.12 RUS90797.1 - 5.5e-07 29.3 1.4 1.8e-06 27.7 0.1 2.4 2 1 0 2 2 2 1 Cadherin-like LLGL PF08366.13 RUS90798.1 - 4.7e-37 126.5 0.2 2.9e-36 124.0 0.0 2.5 3 0 0 3 3 3 1 LLGL2 ANAPC4_WD40 PF12894.7 RUS90798.1 - 3.3e-08 33.7 0.0 0.0056 16.9 0.0 5.4 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS90798.1 - 1.1e-06 29.2 0.2 0.055 14.3 0.1 4.7 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 RUS90798.1 - 0.0033 17.8 0.0 6.5 7.4 0.0 3.7 3 0 0 3 3 3 2 PQQ-like domain DUF2415 PF10313.9 RUS90798.1 - 0.041 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40_like PF17005.5 RUS90798.1 - 0.079 12.3 2.1 2.7 7.2 1.5 3.0 2 1 0 2 2 2 0 WD40-like domain DUF4986 PF16375.5 RUS90798.1 - 0.13 13.0 0.1 0.35 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function CBFD_NFYB_HMF PF00808.23 RUS90798.1 - 0.16 12.3 1.7 0.38 11.1 1.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ZZ PF00569.17 RUS90800.1 - 9.5e-16 57.3 19.2 3.8e-08 33.0 2.1 3.2 3 0 0 3 3 3 2 Zinc finger, ZZ type CUB PF00431.20 RUS90800.1 - 0.011 16.1 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 CUB domain C1_2 PF03107.16 RUS90800.1 - 0.25 11.7 19.6 0.018 15.3 3.4 2.7 2 0 0 2 2 2 0 C1 domain TetR_C_19 PF17924.1 RUS90800.1 - 1.3 9.7 4.8 8 7.1 0.7 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ANAPC10 PF03256.16 RUS90802.1 - 8.2e-13 48.4 1.1 1.4e-12 47.7 1.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Sec16_N PF12935.7 RUS90805.1 - 0.016 15.4 1.7 0.016 15.4 1.7 2.0 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus DUF4485 PF14846.6 RUS90806.1 - 2.9e-23 81.7 0.3 2.9e-23 81.7 0.3 5.1 6 1 0 6 6 6 1 Domain of unknown function (DUF4485) DUF760 PF05542.11 RUS90806.1 - 6.1 7.3 9.5 13 6.3 0.3 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF760) Filament PF00038.21 RUS90806.1 - 6.9 6.2 143.9 0.6 9.6 35.9 5.4 1 1 4 5 5 5 0 Intermediate filament protein SUZ-C PF12901.7 RUS90807.1 - 0.14 12.2 0.6 0.14 12.2 0.6 2.4 2 0 0 2 2 2 0 SUZ-C motif Vps39_2 PF10367.9 RUS90809.1 - 0.065 13.7 0.6 4.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 DUF4209 PF13910.6 RUS90809.1 - 0.13 12.5 0.7 5.8 7.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) V-ATPase_H_C PF11698.8 RUS90809.1 - 0.15 12.2 1.2 1.1 9.4 0.0 2.9 4 0 0 4 4 4 0 V-ATPase subunit H DUF4918 PF16265.5 RUS90810.1 - 0.0008 19.0 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4918) UDG PF03167.19 RUS90810.1 - 0.0041 17.1 0.1 0.043 13.8 0.1 2.2 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Nuf2 PF03800.14 RUS90811.1 - 2.4e-21 76.3 0.5 8.8e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Nuf2 family Pox_A_type_inc PF04508.12 RUS90811.1 - 0.049 13.5 0.4 0.049 13.5 0.4 3.9 4 1 1 5 5 5 0 Viral A-type inclusion protein repeat Cnl2_NKP2 PF09447.10 RUS90811.1 - 1.4 9.1 6.0 1.6 8.9 1.5 3.3 3 1 0 3 3 3 0 Cnl2/NKP2 family protein Spc7 PF08317.11 RUS90811.1 - 4.1 6.2 51.9 2.9 6.7 12.9 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 RUS90811.1 - 5.9 7.4 18.4 0.29 11.6 4.4 4.5 3 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 RUS90811.1 - 5.9 7.0 48.7 0.52 10.4 15.4 3.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Rpr2 PF04032.16 RUS90813.1 - 1.6e-21 76.3 1.9 2.3e-21 75.9 1.9 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 RUS90813.1 - 0.017 15.2 0.7 0.021 14.9 0.7 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain ADD_ATRX PF17981.1 RUS90813.1 - 1.6 8.6 6.5 16 5.5 1.8 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain Ank_2 PF12796.7 RUS90814.1 - 9.1e-27 93.5 1.9 8.4e-13 48.7 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS90814.1 - 1.3e-20 73.4 2.1 1.1e-05 25.9 0.1 5.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS90814.1 - 2.6e-17 62.6 2.0 2.9e-07 30.6 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS90814.1 - 5.7e-14 51.8 2.6 0.0024 18.2 0.0 6.5 6 1 1 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 RUS90814.1 - 3.1e-12 45.5 0.4 0.061 13.9 0.0 7.8 9 0 0 9 9 9 3 Ankyrin repeat Shigella_OspC PF06128.11 RUS90814.1 - 0.031 14.0 0.9 4.9 6.8 0.2 3.4 3 1 1 4 4 4 0 Shigella flexneri OspC protein Pkinase PF00069.25 RUS90815.1 - 4.6e-52 177.0 0.0 4e-51 173.9 0.0 2.5 2 1 0 3 3 3 1 Protein kinase domain IKBKB_SDD PF18397.1 RUS90815.1 - 4.2e-37 128.0 5.1 6.9e-37 127.2 5.1 1.3 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase_Tyr PF07714.17 RUS90815.1 - 1.5e-30 106.4 0.0 6.4e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 RUS90815.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS90815.1 - 0.01 15.2 0.0 0.081 12.2 0.0 2.5 3 0 0 3 3 3 0 Kinase-like TBK1_ULD PF18396.1 RUS90815.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 RUS90815.1 - 0.046 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin family Swm2 PF17083.5 RUS90815.1 - 0.06 13.4 4.1 0.46 10.5 0.8 2.7 2 0 0 2 2 2 0 Nucleolar protein Swm2 APH PF01636.23 RUS90815.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ntox28 PF15605.6 RUS90815.1 - 0.094 13.0 0.7 0.95 9.7 0.4 2.5 2 0 0 2 2 2 0 Bacterial toxin 28 IKKbetaNEMObind PF12179.8 RUS90815.1 - 1.5 9.0 4.7 0.9 9.6 1.5 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain His_Phos_2 PF00328.22 RUS90816.1 - 1.2e-22 80.9 0.0 1.9e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 RUS90816.1 - 0.027 14.2 0.0 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) UPF0149 PF03695.13 RUS90816.1 - 0.11 12.7 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Gar1 PF04410.14 RUS90817.1 - 1.3e-39 135.4 0.1 1.3e-39 135.4 0.1 1.8 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DNA_pol_E_B PF04042.16 RUS90818.1 - 3.5e-41 140.9 0.0 5.2e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 RUS90818.1 - 1.1e-37 129.1 0.0 1.9e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain RVT_1 PF00078.27 RUS90819.1 - 4.9e-24 85.1 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD PF00628.29 RUS90819.1 - 8.3e-06 25.6 10.7 1.5e-05 24.7 10.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RUS90819.1 - 3.6e-05 23.2 3.9 3.6e-05 23.2 3.9 2.1 2 0 0 2 2 2 1 PHD-finger Zn_ribbon_17 PF17120.5 RUS90819.1 - 0.17 11.6 7.5 0.42 10.3 7.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pox_vIL-18BP PF05566.12 RUS90819.1 - 0.28 11.4 3.0 4.4 7.6 0.8 2.4 1 1 1 2 2 2 0 Orthopoxvirus interleukin 18 binding protein C1_2 PF03107.16 RUS90819.1 - 0.4 11.1 7.7 2.5 8.5 4.4 2.3 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 RUS90819.1 - 3.3 8.0 10.3 8.8 6.6 10.3 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 RUS90820.1 - 1.8e-24 86.1 1.9 6.7e-11 42.6 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS90820.1 - 2.1e-21 73.7 7.0 0.00013 22.1 0.1 6.8 7 0 0 7 7 7 4 Ankyrin repeat DHHC PF01529.20 RUS90820.1 - 5.4e-20 71.9 9.9 5.4e-20 71.9 9.9 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 RUS90820.1 - 5.5e-20 71.5 6.2 1.2e-07 32.2 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS90820.1 - 5.9e-19 67.9 3.1 0.00037 20.7 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 RUS90820.1 - 3.2e-18 65.3 10.3 2.1e-05 24.8 0.4 6.5 7 0 0 7 7 7 4 Ankyrin repeat UPF0547 PF10571.9 RUS90820.1 - 0.69 10.0 4.2 1.6 8.9 4.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 p25-alpha PF05517.12 RUS90821.1 - 2.5e-20 73.2 7.4 3.6e-20 72.7 7.4 1.2 1 0 0 1 1 1 1 p25-alpha Pkinase PF00069.25 RUS90822.1 - 3.3e-43 147.9 0.0 3.7e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90822.1 - 4.2e-28 98.3 0.0 4.9e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS90822.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDHD PF02862.17 RUS90823.1 - 0.00072 19.8 3.6 0.00076 19.7 3.6 1.3 1 0 0 1 1 1 1 DDHD domain Connexin PF00029.19 RUS90823.1 - 0.014 15.2 18.6 0.021 14.6 18.6 1.3 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 RUS90823.1 - 0.022 13.6 23.9 0.028 13.2 23.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4228 PF14009.6 RUS90823.1 - 0.024 15.0 9.5 0.032 14.6 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RPOL_N PF14700.6 RUS90823.1 - 0.028 13.8 20.5 0.039 13.3 20.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Zip PF02535.22 RUS90823.1 - 0.035 13.3 8.9 0.042 13.1 8.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 RUS90823.1 - 0.041 13.2 15.0 0.13 11.5 15.5 1.7 2 0 0 2 2 2 0 Prim-pol family 5 DUF4050 PF13259.6 RUS90823.1 - 0.054 13.8 10.2 0.073 13.4 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Otopetrin PF03189.13 RUS90823.1 - 0.077 11.8 6.8 0.089 11.6 6.8 1.1 1 0 0 1 1 1 0 Otopetrin CPSF100_C PF13299.6 RUS90823.1 - 0.082 13.1 15.8 0.14 12.4 15.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 RUS90823.1 - 0.084 13.0 20.5 0.13 12.4 20.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF5308 PF17233.2 RUS90823.1 - 0.096 12.9 2.2 0.12 12.6 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Pkinase_fungal PF17667.1 RUS90823.1 - 0.24 10.1 10.4 0.29 9.9 10.4 1.1 1 0 0 1 1 1 0 Fungal protein kinase RNA_pol_Rpc4 PF05132.14 RUS90823.1 - 0.27 11.7 23.9 0.44 11.0 23.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 RUS90823.1 - 0.28 9.9 15.9 0.37 9.5 15.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 RUS90823.1 - 0.34 9.5 17.0 0.4 9.2 17.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SLC12 PF03522.15 RUS90823.1 - 0.56 9.2 21.9 0.66 8.9 21.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ICA69 PF04629.14 RUS90823.1 - 0.82 9.9 16.9 1.1 9.5 16.9 1.2 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain LicD PF04991.13 RUS90823.1 - 0.98 9.5 25.8 1.4 9.0 25.8 1.2 1 0 0 1 1 1 0 LicD family DUF2370 PF10176.9 RUS90823.1 - 1.6 8.4 5.6 2.2 7.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RP-C_C PF11800.8 RUS90823.1 - 1.8 8.6 9.1 2.4 8.2 9.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Tim54 PF11711.8 RUS90823.1 - 1.9 7.2 24.4 2.7 6.7 24.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MDM10 PF12519.8 RUS90823.1 - 2.1 7.1 19.1 2.7 6.8 19.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hydin_ADK PF17213.3 RUS90823.1 - 2.1 8.6 9.7 3.2 8.0 9.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Membralin PF09746.9 RUS90823.1 - 4.1 6.4 12.9 5.2 6.0 12.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein Ndc1_Nup PF09531.10 RUS90823.1 - 4.8 5.8 7.9 5.4 5.6 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 RUS90823.1 - 7.5 6.3 14.5 11 5.7 14.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Vfa1 PF08432.10 RUS90823.1 - 7.7 6.8 44.8 12 6.1 44.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.16 RUS90823.1 - 9.2 6.2 16.4 13 5.7 16.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LCM PF04072.14 RUS90824.1 - 3.6e-28 98.8 0.0 1.2e-27 97.1 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4272 PF14094.6 RUS90824.1 - 0.059 12.6 0.4 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) CDC27 PF09507.10 RUS90825.1 - 1.6e-65 222.2 58.1 2e-65 221.9 58.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 FAM194 PF14977.6 RUS90826.1 - 6.3e-63 211.8 0.0 1.2e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 FAM194 protein SSF PF00474.17 RUS90827.1 - 2.2e-39 135.5 25.8 3.1e-39 135.0 25.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family TMC PF07810.13 RUS90828.1 - 3.9e-39 133.7 2.0 3.9e-39 133.7 2.0 3.1 4 0 0 4 4 4 1 TMC domain YebO PF13974.6 RUS90828.1 - 0.0074 16.3 0.1 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 YebO-like protein Aminotran_3 PF00202.21 RUS90829.1 - 2.8e-105 352.3 0.0 3.3e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.21 RUS90830.1 - 2.7e-82 276.6 0.0 6.3e-81 272.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III LIM PF00412.22 RUS90831.1 - 4.3e-33 113.3 28.1 5.6e-12 45.7 5.9 3.2 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 RUS90831.1 - 3.6e-13 49.7 0.0 7.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 RUS90831.1 - 1.7e-11 45.1 5.7 9.5e-10 39.5 0.6 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 RUS90831.1 - 1.4e-09 37.7 0.1 2.5e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS90831.1 - 7.9e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-RRN7 PF11781.8 RUS90831.1 - 0.02 14.6 0.4 0.02 14.6 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PDZ PF00595.24 RUS90832.1 - 9.3e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 RUS90832.1 - 2.3e-12 46.9 2.4 3.9e-12 46.2 2.4 1.3 1 0 0 1 1 1 1 LIM domain DUF4749 PF15936.5 RUS90832.1 - 6.1e-10 40.1 0.1 1.2e-09 39.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 RUS90832.1 - 2.4e-09 36.9 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS90832.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 1 0 1 1 1 1 PDZ domain Ribosomal_L9_C PF03948.14 RUS90833.1 - 8.6 6.9 6.2 1.1e+02 3.4 0.1 4.5 3 1 2 5 5 5 0 Ribosomal protein L9, C-terminal domain Acyl_transf_1 PF00698.21 RUS90834.1 - 3.7e-82 276.4 0.0 5.3e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 RUS90834.1 - 5.8e-62 209.6 0.1 1.1e-61 208.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RUS90834.1 - 1.7e-38 131.3 0.0 3.4e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 RUS90834.1 - 6.8e-31 107.0 0.4 5.6e-30 104.1 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 RUS90834.1 - 2.6e-20 72.9 0.0 5.6e-20 71.8 0.0 1.4 1 1 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.6 RUS90834.1 - 4.8e-05 23.3 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 RUS90834.1 - 0.029 13.8 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 RUS90834.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 RUS90834.1 - 0.15 12.8 0.0 0.58 10.9 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 RUS90835.1 - 8.7e-61 205.6 0.0 1.1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90835.1 - 5.1e-34 117.7 0.0 6.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 RUS90835.1 - 0.0022 17.6 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RUS90835.1 - 0.0027 16.7 0.1 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RUS90835.1 - 0.0042 16.4 0.0 0.0087 15.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RUS90835.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS90835.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RUS90835.1 - 0.072 13.0 0.1 0.19 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family SHIPPO-rpt PF07004.12 RUS90836.1 - 4.8e-17 62.0 43.0 1.3e-06 29.1 2.3 6.7 7 0 0 7 7 7 6 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 RUS90837.1 - 1.6e-15 57.2 35.6 7.8e-05 23.4 0.5 6.4 6 2 0 6 6 6 4 Sperm-tail PG-rich repeat Rapsyn_N PF10579.9 RUS90838.1 - 6.5e-17 61.4 0.6 3e-16 59.3 0.2 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.6 RUS90838.1 - 2.5e-07 30.2 0.1 0.63 10.2 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RUS90838.1 - 9.8e-07 28.3 3.5 0.0014 18.3 0.3 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RUS90838.1 - 3.2e-06 26.8 4.2 0.016 15.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RUS90838.1 - 3.3e-06 27.3 0.5 0.0044 17.3 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 RUS90838.1 - 4.8e-05 23.6 3.4 0.00018 21.8 3.4 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS90838.1 - 0.00025 20.9 2.4 0.0007 19.5 2.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS90838.1 - 0.0012 18.6 2.3 0.0031 17.3 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SLT_L PF14718.6 RUS90838.1 - 0.0054 16.8 0.1 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 Soluble lytic murein transglycosylase L domain zf-C3HC4 PF00097.25 RUS90838.1 - 0.0058 16.5 1.0 0.016 15.1 1.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS90838.1 - 0.012 15.6 0.5 0.038 14.0 0.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger C1_1 PF00130.22 RUS90838.1 - 0.22 11.4 0.2 0.22 11.4 0.2 2.9 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_8 PF13181.6 RUS90838.1 - 7.8 7.0 6.0 14 6.2 0.5 3.7 4 1 1 5 5 4 0 Tetratricopeptide repeat LRR_8 PF13855.6 RUS90839.1 - 2.7e-40 135.9 24.3 3.2e-15 55.6 5.3 5.9 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 RUS90839.1 - 1.6e-29 101.5 28.8 7e-06 26.3 1.4 8.4 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS90839.1 - 1e-15 55.9 29.0 0.19 12.4 0.0 12.1 13 0 0 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.6 RUS90839.1 - 8.4e-11 41.0 31.9 0.62 10.3 0.4 11.5 12 0 0 12 12 12 4 Leucine Rich repeat LRR_5 PF13306.6 RUS90839.1 - 9.6e-11 41.8 0.0 9.2e-09 35.3 0.1 2.9 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS90839.1 - 1.3e-05 24.8 6.8 0.33 10.4 0.6 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_2 PF07723.13 RUS90839.1 - 9 7.2 8.0 91 4.0 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat MIT_LIKE_ACTX PF17556.2 RUS90840.1 - 0.0095 16.5 8.1 0.029 14.9 8.1 1.8 1 1 0 1 1 1 1 MIT-like atracotoxin family Prokineticin PF06607.11 RUS90840.1 - 0.089 13.1 2.4 0.45 10.9 2.4 2.0 1 1 0 1 1 1 0 Prokineticin Tachystatin_A PF11406.8 RUS90840.1 - 0.97 9.6 7.0 1.9 8.6 1.0 2.4 1 1 1 2 2 2 0 Antimicrobial peptide tachystatin A YlmH_RBD PF17774.1 RUS90841.1 - 0.0046 17.2 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Putative RNA-binding domain in YlmH His_Phos_1 PF00300.22 RUS90841.1 - 0.013 15.2 0.4 5.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) CZB PF13682.6 RUS90841.1 - 0.022 15.2 0.9 8.9 6.8 0.1 2.4 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain Asp4 PF16996.5 RUS90841.1 - 0.047 13.5 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 DUF2482 PF10655.9 RUS90841.1 - 0.055 14.0 0.0 18 5.9 0.0 2.3 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Vps53_N PF04100.12 RUS90841.1 - 0.12 11.3 0.5 4.3 6.2 0.0 2.0 2 0 0 2 2 2 0 Vps53-like, N-terminal Col_cuticle_N PF01484.17 RUS90841.1 - 0.18 11.9 1.0 20 5.3 0.1 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain TOH_N PF12549.8 RUS90841.1 - 0.66 9.9 3.4 21 5.1 0.0 2.7 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal NHS PF15273.6 RUS90842.1 - 3.3e-12 46.3 30.2 1.2e-11 44.5 30.2 1.8 1 1 0 1 1 1 1 NHS-like Peptidase_M50 PF02163.22 RUS90843.1 - 1.7e-22 79.9 0.1 2e-21 76.4 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M50 RMI1_N PF08585.12 RUS90844.1 - 1.8e-48 165.2 0.7 4.7e-48 163.8 0.2 2.0 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 RUS90845.1 - 2.2e-19 69.7 0.0 2.6e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Pro_isomerase PF00160.21 RUS90846.1 - 2.9e-43 147.9 0.0 3.7e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DNA_pol_alpha_N PF12254.8 RUS90846.1 - 0.14 12.2 0.2 0.36 11.0 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.32 RUS90847.1 - 6.5e-08 33.1 14.1 0.0015 19.3 0.3 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS90847.1 - 9.9e-06 25.8 0.6 0.068 13.5 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 RUS90849.1 - 5.5e-41 139.0 0.0 2.1e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain TFIIA PF03153.13 RUS90849.1 - 0.036 14.1 17.7 0.053 13.5 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 RUS90849.1 - 0.31 11.2 15.9 0.8 9.8 15.9 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DDHD PF02862.17 RUS90849.1 - 8.3 6.5 10.1 4.1 7.5 7.6 1.7 2 0 0 2 2 2 0 DDHD domain FYVE_2 PF02318.16 RUS90850.1 - 1e-08 35.4 3.1 3.2e-08 33.8 3.1 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger OSCP PF00213.18 RUS90852.1 - 1.5e-43 148.9 3.4 2e-43 148.5 3.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit FAA_hydrolase_N PF09298.11 RUS90852.1 - 0.004 17.3 2.2 1.8 8.8 0.3 3.1 2 1 1 3 3 3 2 Fumarylacetoacetase N-terminal Atg14 PF10186.9 RUS90852.1 - 0.013 14.6 3.0 0.016 14.3 3.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CUB PF00431.20 RUS90853.1 - 7.6e-14 52.0 0.0 9.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sugar_tr PF00083.24 RUS90855.1 - 1.7e-34 119.5 3.5 2.2e-34 119.1 3.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS90855.1 - 6.5e-30 104.2 37.5 3.2e-23 82.2 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RUS90855.1 - 5.5e-06 25.1 8.0 0.00057 18.4 1.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 RUS90855.1 - 0.21 10.1 18.5 0.082 11.4 3.8 2.8 2 2 0 2 2 2 0 MFS/sugar transport protein DDE_1 PF03184.19 RUS90856.1 - 4.4e-21 75.3 0.1 1.2e-20 73.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 RUS90856.1 - 8.4e-10 38.5 0.0 2.6e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 RUS90856.1 - 6.6e-06 25.8 0.0 1.5e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain VWA PF00092.28 RUS90856.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DDE_3 PF13358.6 RUS90856.1 - 0.0097 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r1_2 PF00140.20 RUS90856.1 - 7 6.8 5.1 0.8 9.8 0.4 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 DUF3750 PF12570.8 RUS90857.1 - 0.017 15.8 0.2 0.47 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) C6 PF01681.17 RUS90858.1 - 0.26 11.9 7.9 1.7 9.2 1.2 3.3 3 1 0 3 3 3 0 C6 domain adh_short_C2 PF13561.6 RUS90861.1 - 6.1e-54 183.1 0.0 7.5e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS90861.1 - 1.9e-45 154.8 0.0 2.3e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS90861.1 - 0.00017 21.5 0.1 0.00026 21.0 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS90861.1 - 0.03 13.6 0.0 0.14 11.5 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Spheroidin PF05541.12 RUS90861.1 - 0.071 10.9 0.0 0.09 10.6 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein adh_short_C2 PF13561.6 RUS90862.1 - 1.8e-52 178.3 0.0 2.2e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS90862.1 - 4.4e-45 153.5 0.0 5.6e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS90862.1 - 3.5e-06 27.1 0.1 4.9e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 RUS90862.1 - 0.00051 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 RUS90862.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Carn_acyltransf PF00755.20 RUS90864.1 - 1.1e-203 678.1 0.0 1.3e-203 677.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 RUS90864.1 - 3e-22 78.4 0.8 5.9e-22 77.4 0.2 1.9 2 0 0 2 2 2 1 Carnitine O-palmitoyltransferase N-terminus CENP-T_C PF15511.6 RUS90864.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RHH_7 PF16777.5 RUS90864.1 - 0.14 12.6 0.1 0.48 10.8 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG EF-hand_6 PF13405.6 RUS90866.1 - 0.037 14.0 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 RUS90866.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 RUS90866.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 RUS90866.1 - 0.18 11.5 0.0 0.46 10.1 0.0 1.7 1 0 0 1 1 1 0 EF hand zf-CCHC_3 PF13917.6 RUS90867.1 - 0.00044 20.2 2.2 0.0013 18.7 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS90867.1 - 0.023 14.4 3.4 0.064 13.0 3.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 RUS90867.1 - 1.8 8.8 6.0 0.27 11.4 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle SRP-alpha_N PF04086.13 RUS90867.1 - 8.1 6.3 10.3 12 5.7 10.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4797 PF16051.5 RUS90868.1 - 1.7e-11 43.8 56.5 1.8 8.6 0.4 11.1 1 1 10 11 11 11 11 Domain of unknown function (DUF4797) ENOD40 PF08247.11 RUS90868.1 - 0.016 15.2 9.4 97 3.3 0.1 8.6 11 0 0 11 11 11 0 ENOD40 protein Pox_polyA_pol_N PF12630.7 RUS90868.1 - 0.71 10.3 7.1 46 4.4 0.1 4.0 1 1 5 6 6 6 0 Poxvirus poly(A) polymerase N-terminal domain Arm PF00514.23 RUS90870.1 - 3.8e-05 23.6 1.1 1.3 9.2 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat PUL PF08324.11 RUS90870.1 - 0.0011 18.3 4.2 1.4 8.1 2.5 3.6 2 2 1 3 3 3 3 PUL domain DUF383 PF04063.14 RUS90870.1 - 0.39 10.4 2.3 12 5.5 0.9 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF383) Methyltr_RsmB-F PF01189.17 RUS90871.1 - 3.1e-26 92.3 0.0 4.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RUS90871.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TauD PF02668.16 RUS90874.1 - 2.8e-36 125.7 0.1 2.8e-36 125.7 0.1 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 RUS90874.1 - 2.4e-10 40.9 0.1 2.4e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 RUS90874.1 - 0.0096 15.1 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 CsiD Sugar_tr PF00083.24 RUS90876.1 - 3.4e-20 72.4 5.2 7e-20 71.3 5.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS90876.1 - 1e-09 37.8 26.6 4.9e-08 32.3 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_10 PF13374.6 RUS90876.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SKG6 PF08693.10 RUS90876.1 - 1.1 8.7 4.6 3.6 7.1 0.7 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sod_Cu PF00080.20 RUS90878.1 - 1.8e-44 151.4 2.0 2.1e-44 151.1 2.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) 7tm_1 PF00001.21 RUS90879.1 - 1.1e-19 70.9 4.2 1.3e-19 70.6 4.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C3HC4 PF00097.25 RUS90880.1 - 8.4e-06 25.6 3.1 8.4e-06 25.6 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS90880.1 - 1.3e-05 25.1 2.3 3.7e-05 23.6 2.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RUS90880.1 - 1.9e-05 24.4 4.9 1.9e-05 24.4 4.9 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RUS90880.1 - 8.2e-05 22.7 1.0 8.2e-05 22.7 1.0 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RUS90880.1 - 0.00012 21.9 10.3 0.00013 21.8 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS90880.1 - 0.00014 21.7 6.8 0.00014 21.7 6.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RUS90880.1 - 0.00024 20.9 3.6 0.00024 20.9 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS90880.1 - 0.00081 19.7 5.7 0.00081 19.7 5.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 RUS90880.1 - 0.087 13.0 2.9 0.077 13.1 1.2 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-MIZ PF02891.20 RUS90880.1 - 0.86 9.4 5.7 1.8 8.4 5.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_10 PF16685.5 RUS90880.1 - 1.4 9.1 7.5 0.38 10.9 4.0 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4118 PF13493.6 RUS90882.1 - 4.2 7.2 11.3 72 3.2 2.7 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4118) PID PF00640.23 RUS90884.1 - 3.3e-15 56.4 0.7 5.4e-15 55.7 0.7 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 RUS90884.1 - 1.7e-13 50.9 1.1 2.4e-13 50.4 1.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 RUS90884.1 - 0.00055 20.1 0.1 0.0013 18.9 0.1 1.5 2 0 0 2 2 2 1 Phosphotyrosine-binding domain PI3_PI4_kinase PF00454.27 RUS90885.1 - 6.9e-36 124.3 0.0 9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RUS90885.1 - 5.8e-16 58.0 0.1 1.4e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 RUS90886.1 - 4.1e-08 32.8 2.8 2.6e-07 30.2 2.8 2.3 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 RUS90886.1 - 2.7e-05 24.1 0.1 6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RepC PF06504.11 RUS90886.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Replication protein C (RepC) HEAT_2 PF13646.6 RUS90886.1 - 0.13 12.7 0.1 1.6 9.2 0.1 3.0 3 0 0 3 3 3 0 HEAT repeats DUF3106 PF11304.8 RUS90887.1 - 0.073 13.5 0.0 28 5.2 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF4156 PF13698.6 RUS90887.1 - 8.7 6.8 20.9 1.1e+02 3.2 0.2 5.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4156) TAN PF11640.8 RUS90888.1 - 4.1e-16 59.5 2.7 7e-16 58.7 2.7 1.4 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair ATPgrasp_TupA PF14305.6 RUS90888.1 - 0.19 11.5 1.2 9.6 5.9 0.1 2.1 2 0 0 2 2 2 0 TupA-like ATPgrasp BUD22 PF09073.10 RUS90889.1 - 1.7e-09 37.6 17.9 1.7e-09 37.5 17.9 1.1 1 0 0 1 1 1 1 BUD22 Caldesmon PF02029.15 RUS90889.1 - 5.7e-07 28.7 20.5 5.7e-07 28.7 20.5 1.1 1 0 0 1 1 1 1 Caldesmon Pox_Ag35 PF03286.14 RUS90889.1 - 4.6e-05 23.3 24.9 7.2e-05 22.7 24.9 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Mpp10 PF04006.12 RUS90889.1 - 0.00042 18.9 33.2 0.00053 18.6 33.2 1.1 1 0 0 1 1 1 1 Mpp10 protein NPR3 PF03666.13 RUS90889.1 - 0.00048 19.0 15.0 0.00059 18.8 15.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 RUS90889.1 - 0.0005 18.5 30.5 0.00063 18.1 30.5 1.1 1 0 0 1 1 1 1 Nop14-like family Zip PF02535.22 RUS90889.1 - 0.001 18.4 7.5 0.0012 18.2 7.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DDHD PF02862.17 RUS90889.1 - 0.0011 19.2 1.5 0.0013 18.9 1.5 1.3 1 0 0 1 1 1 1 DDHD domain DUF913 PF06025.12 RUS90889.1 - 0.0023 17.0 10.1 0.0028 16.7 10.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 RUS90889.1 - 0.0024 18.2 23.9 0.0036 17.6 23.9 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Gti1_Pac2 PF09729.9 RUS90889.1 - 0.0032 17.6 9.4 0.0045 17.1 9.4 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Presenilin PF01080.17 RUS90889.1 - 0.0041 15.9 14.4 0.005 15.7 14.4 1.1 1 0 0 1 1 1 1 Presenilin SpoIIP PF07454.11 RUS90889.1 - 0.0067 15.9 16.0 0.009 15.5 16.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF2151 PF10221.9 RUS90889.1 - 0.007 15.0 12.9 0.0082 14.8 12.9 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator FAM60A PF15396.6 RUS90889.1 - 0.0077 16.3 13.6 0.012 15.7 13.6 1.2 1 0 0 1 1 1 1 Protein Family FAM60A MCM_bind PF09739.9 RUS90889.1 - 0.017 13.6 13.0 0.021 13.3 13.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4045 PF13254.6 RUS90889.1 - 0.018 14.7 13.8 0.024 14.3 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RNA_pol_Rpc4 PF05132.14 RUS90889.1 - 0.019 15.4 14.0 0.033 14.6 14.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1754 PF08555.10 RUS90889.1 - 0.02 15.7 38.2 0.043 14.6 38.2 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF5308 PF17233.2 RUS90889.1 - 0.029 14.6 1.7 0.04 14.2 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SAPS PF04499.15 RUS90889.1 - 0.032 13.0 12.5 0.041 12.7 12.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BORG_CEP PF14957.6 RUS90889.1 - 0.033 15.3 10.4 0.06 14.5 10.4 1.5 1 0 0 1 1 1 0 Cdc42 effector FGF-BP1 PF06473.12 RUS90889.1 - 0.041 13.7 19.2 0.073 12.9 19.2 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_pol_3_Rpc31 PF11705.8 RUS90889.1 - 0.053 13.8 40.5 0.077 13.2 40.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Rrn6 PF10214.9 RUS90889.1 - 0.083 11.4 9.2 0.1 11.1 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Cwf_Cwc_15 PF04889.12 RUS90889.1 - 0.084 12.6 27.1 0.12 12.1 27.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4551 PF15087.6 RUS90889.1 - 0.1 11.4 10.0 0.13 11.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 RUS90889.1 - 0.14 10.1 19.6 0.18 9.7 19.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 RUS90889.1 - 0.17 11.3 35.6 0.23 10.8 35.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Raftlin PF15250.6 RUS90889.1 - 0.19 10.4 11.0 0.22 10.2 11.0 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 RUS90889.1 - 0.22 10.5 13.2 0.29 10.1 13.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 RUS90889.1 - 0.25 10.7 29.1 0.34 10.2 29.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.14 RUS90889.1 - 0.32 9.2 25.9 0.43 8.8 25.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.12 RUS90889.1 - 0.37 10.6 38.3 0.72 9.7 38.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) AAA_11 PF13086.6 RUS90889.1 - 0.4 10.4 14.1 0.59 9.9 14.1 1.2 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 RUS90889.1 - 0.4 10.4 17.2 0.73 9.5 17.2 1.4 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 RUS90889.1 - 0.41 8.7 12.4 0.47 8.5 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSRNP_N PF16019.5 RUS90889.1 - 0.41 10.5 15.1 0.65 9.9 15.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Endostatin PF06482.11 RUS90889.1 - 0.47 9.9 7.1 0.65 9.4 7.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TERB2 PF15101.6 RUS90889.1 - 0.54 10.3 8.7 0.82 9.7 8.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cellulose_synt PF03552.14 RUS90889.1 - 0.57 8.6 8.2 0.67 8.4 8.2 1.1 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.8 RUS90889.1 - 0.7 8.7 28.0 0.96 8.3 28.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NOA36 PF06524.12 RUS90889.1 - 0.7 9.2 26.5 1.3 8.3 26.5 1.4 1 0 0 1 1 1 0 NOA36 protein Spore_coat_CotO PF14153.6 RUS90889.1 - 0.73 9.7 31.2 1.2 9.0 31.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.16 RUS90889.1 - 0.77 8.9 20.1 1.1 8.4 20.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF5427 PF10310.9 RUS90889.1 - 0.77 8.6 26.7 1 8.2 26.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RR_TM4-6 PF06459.12 RUS90889.1 - 0.79 9.5 31.9 1.1 9.0 31.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 RUS90889.1 - 0.92 8.2 24.5 1.6 7.5 24.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF262 PF03235.14 RUS90889.1 - 1.3 9.2 9.5 1.7 8.8 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Neur_chan_memb PF02932.16 RUS90889.1 - 1.5 8.8 10.6 2.2 8.3 10.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.11 RUS90889.1 - 1.5 7.2 13.6 1.9 6.9 13.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Smg8_Smg9 PF10220.9 RUS90889.1 - 1.7 6.9 13.2 2.1 6.6 13.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 RP-C_C PF11800.8 RUS90889.1 - 1.9 8.5 12.1 2.6 8.1 12.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DNA_pol_phi PF04931.13 RUS90889.1 - 2 6.4 43.3 2.6 6.0 43.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPOL_N PF14700.6 RUS90889.1 - 2.1 7.7 18.3 2.9 7.2 18.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal ASC PF00858.24 RUS90889.1 - 2.1 7.2 8.4 2.8 6.8 8.4 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel eIF3_subunit PF08597.10 RUS90889.1 - 2.5 8.0 45.1 3.7 7.4 45.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MDM1 PF15501.6 RUS90889.1 - 2.7 7.1 25.9 3.8 6.5 25.9 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 VIR_N PF15912.5 RUS90889.1 - 3 7.4 25.4 4.3 6.9 25.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CENP-N PF05238.13 RUS90889.1 - 3.2 7.0 13.2 4.5 6.5 13.2 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CSG2 PF16965.5 RUS90889.1 - 3.3 6.5 9.9 4.3 6.2 9.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 RUS90889.1 - 3.6 5.9 8.5 4.2 5.6 8.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2828 PF11443.8 RUS90889.1 - 3.9 5.4 18.7 5.3 5.0 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Serinc PF03348.15 RUS90889.1 - 3.9 6.3 10.7 5 6.0 10.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CAF1 PF04857.20 RUS90889.1 - 4.2 6.4 12.3 5 6.2 12.3 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF2370 PF10176.9 RUS90889.1 - 4.3 6.9 6.3 5.9 6.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PA26 PF04636.13 RUS90889.1 - 4.7 6.0 15.1 5.9 5.7 15.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MDM10 PF12519.8 RUS90889.1 - 4.8 5.9 13.6 6.1 5.6 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3306 PF11748.8 RUS90889.1 - 5.1 8.0 23.0 8.4 7.3 23.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Afi1 PF07792.12 RUS90889.1 - 7.3 7.1 24.8 13 6.2 24.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking OATP PF03137.20 RUS90889.1 - 7.5 4.7 8.7 11 4.2 8.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 RUS90889.1 - 8.9 5.0 14.2 12 4.6 14.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 RUS90889.1 - 9.4 5.5 38.5 18 4.6 38.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RIBIOP_C PF04950.12 RUS90889.1 - 9.4 5.6 13.9 12 5.2 13.9 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Sec62 PF03839.16 RUS90889.1 - 9.5 5.7 23.9 15 5.1 23.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tub PF01167.18 RUS90890.1 - 4.4e-31 108.5 0.0 1.1e-26 94.1 0.4 2.9 2 1 0 2 2 2 2 Tub family ANAPC4_WD40 PF12894.7 RUS90890.1 - 4.3e-06 26.9 0.4 0.026 14.8 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Involucrin_N PF10583.9 RUS90890.1 - 0.028 15.0 1.7 3 8.5 0.1 3.1 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus IKI3 PF04762.12 RUS90890.1 - 0.036 12.1 0.0 0.056 11.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family SOCS_box PF07525.16 RUS90890.1 - 0.16 12.3 3.4 0.36 11.2 3.4 1.6 1 0 0 1 1 1 0 SOCS box WD40 PF00400.32 RUS90890.1 - 0.2 12.6 4.7 12 6.9 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat p6 PF17548.2 RUS90891.1 - 0.013 15.4 0.6 13 5.8 0.0 3.4 1 1 2 3 3 3 0 Histone-like Protein p6 Alanine_zipper PF11839.8 RUS90891.1 - 0.27 11.6 20.6 1.2e+02 3.1 20.6 2.9 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein S_layer_C PF05124.12 RUS90892.1 - 0.086 12.8 7.4 11 6.0 0.1 4.4 1 1 3 5 5 5 0 S-layer like family, C-terminal region Flavodoxin_NdrI PF07972.11 RUS90892.1 - 0.65 10.2 1.2 19 5.5 0.2 3.0 1 1 1 2 2 2 0 NrdI Flavodoxin like HRM PF02793.22 RUS90892.1 - 1.7 9.0 12.6 10 6.5 0.2 4.2 1 1 5 6 6 6 0 Hormone receptor domain Endopep_inhib PF16800.5 RUS90893.1 - 3e-07 30.5 1.4 0.93 9.4 0.0 4.4 1 1 4 5 5 5 3 IseA DL-endopeptidase inhibitor DUF1836 PF08876.11 RUS90893.1 - 1.5e-05 24.9 3.8 0.17 12.0 0.2 4.1 1 1 2 3 3 3 3 Domain of unknown function (DUF1836) lci PF12197.8 RUS90893.1 - 0.0038 17.0 0.1 2.2 8.1 0.0 3.6 4 0 0 4 4 4 1 Bacillus cereus group antimicrobial protein HTH_WhiA PF02650.14 RUS90893.1 - 0.0075 16.6 9.9 17 5.8 0.2 6.2 1 1 5 6 6 6 1 WhiA C-terminal HTH domain DUF2624 PF11116.8 RUS90893.1 - 0.05 14.5 0.1 50 4.9 0.0 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF2624) Symplekin_C PF12295.8 RUS90893.1 - 0.092 12.8 0.2 4.4 7.4 0.0 2.1 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal DUF4886 PF16227.5 RUS90893.1 - 0.11 11.6 4.0 4.1 6.5 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4886) RecC_C PF17946.1 RUS90893.1 - 1 9.1 7.5 1e+02 2.6 7.5 2.6 1 1 0 1 1 1 0 RecC C-terminal domain HTH_Tnp_Tc3_1 PF11427.8 RUS90893.1 - 1.4 8.8 51.9 17 5.4 0.3 10.4 2 1 9 11 11 11 0 Tc3 transposase ATG11 PF10377.9 RUS90893.1 - 4.6 7.3 6.6 1.7e+03 -1.0 6.6 4.5 1 1 0 1 1 1 0 Autophagy-related protein 11 DUF2198 PF09964.9 RUS90894.1 - 3.7 7.7 5.4 20 5.3 0.3 3.0 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2198) Pro_sub2 PF18513.1 RUS90896.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Prodomain subtilisin 2 DDE_Tnp_IS1595 PF12762.7 RUS90899.1 - 7.7e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain MULE PF10551.9 RUS90899.1 - 4.1e-08 33.5 0.1 1.1e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF2937 PF11157.8 RUS90899.1 - 0.1 12.3 4.7 0.12 12.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) KxDL PF10241.9 RUS90899.1 - 0.19 12.0 1.9 0.95 9.8 1.6 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein Rootletin PF15035.6 RUS90899.1 - 0.31 11.1 5.6 27 4.7 0.4 3.4 4 0 0 4 4 4 0 Ciliary rootlet component, centrosome cohesion Ribosomal_L6e_N PF03868.15 RUS90901.1 - 5.6 7.3 13.4 87 3.5 0.3 4.7 1 1 6 7 7 7 0 Ribosomal protein L6, N-terminal domain AbiJ_NTD3 PF18860.1 RUS90903.1 - 0.15 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 PIF1 PF05970.14 RUS90904.1 - 9.7e-19 67.7 0.1 1.7e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 RUS90904.1 - 3.5e-05 24.1 0.1 5.5e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 RUS90904.1 - 0.0031 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RUS90904.1 - 0.0074 16.7 0.1 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain DUF2791 PF10923.8 RUS90904.1 - 0.028 13.3 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) SPECT1 PF18680.1 RUS90904.1 - 0.036 13.7 1.3 7.3 6.2 0.0 2.9 2 1 1 3 3 3 0 Plasmodium host cell traversal SPECT1 ResIII PF04851.15 RUS90904.1 - 0.062 13.3 0.2 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RUS90904.1 - 0.14 12.5 0.5 0.35 11.2 0.3 1.8 2 0 0 2 2 2 0 AAA domain PDZ PF00595.24 RUS90904.1 - 0.16 12.3 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 PDZ domain Cwf_Cwc_15 PF04889.12 RUS90906.1 - 0.61 9.8 3.1 0.77 9.4 3.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PARP PF00644.20 RUS90907.1 - 1.2e-27 96.7 3.8 1.3e-26 93.4 3.8 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 RUS90907.1 - 3e-09 37.3 0.4 9.6e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 WWE domain 7tm_1 PF00001.21 RUS90908.1 - 3.1e-46 157.8 13.0 3.9e-46 157.5 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS90908.1 - 3.4e-09 36.5 12.6 5.9e-09 35.7 12.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 RUS90908.1 - 3.9e-06 26.4 13.8 1.5e-05 24.5 13.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS90908.1 - 4e-06 26.7 16.7 6.8e-06 25.9 15.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS90908.1 - 0.001 18.8 8.0 0.0067 16.2 6.7 2.2 2 1 0 2 2 2 1 Olfactory receptor DUF4179 PF13786.6 RUS90908.1 - 0.014 15.9 1.0 1.6 9.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) TctB PF07331.11 RUS90908.1 - 0.24 11.7 6.8 0.75 10.1 0.2 3.1 2 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.16 RUS90909.1 - 4.4e-50 170.6 28.4 1.9e-48 165.2 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS90909.1 - 3.9e-10 39.2 15.2 1.1e-09 37.8 14.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 RUS90909.1 - 3.8e-06 26.4 1.7 3.8e-06 26.4 1.7 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 RUS90909.1 - 0.43 10.9 0.1 0.43 10.9 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 RUS90910.1 - 6e-43 147.1 23.9 1.9e-40 138.9 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS90910.1 - 0.0022 16.9 22.7 0.059 12.2 4.6 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter DUF1435 PF07256.12 RUS90910.1 - 0.049 13.7 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Mlh1_C PF16413.5 RUS90912.1 - 9e-95 317.1 0.1 1.5e-94 316.4 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 RUS90912.1 - 3.2e-34 117.2 0.2 6.9e-34 116.1 0.2 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RUS90912.1 - 1.7e-13 50.6 0.1 3.7e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RUS90912.1 - 7.9e-08 32.8 0.1 2.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase S_100 PF01023.19 RUS90912.1 - 0.21 11.3 1.2 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain HAGH_C PF16123.5 RUS90913.1 - 4e-26 91.3 0.0 6.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RUS90913.1 - 8.5e-13 48.8 1.9 8.7e-09 35.7 0.4 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RUS90913.1 - 0.038 13.5 0.3 0.072 12.6 0.3 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RUS90913.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Erv26 PF04148.13 RUS90914.1 - 1.3e-52 178.6 22.6 5.5e-52 176.6 22.6 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ank_4 PF13637.6 RUS90915.1 - 1.8e-22 79.4 0.8 6.9e-09 36.1 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS90915.1 - 5.6e-22 78.1 0.0 4.9e-11 43.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS90915.1 - 1e-13 51.2 0.0 5.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS90915.1 - 2.3e-11 42.9 1.1 0.00026 21.2 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RUS90915.1 - 9.6e-11 41.6 1.8 0.00057 20.2 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat DUF4207 PF13904.6 RUS90915.1 - 1.2 8.8 16.2 0.077 12.7 11.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Enolase_C PF00113.22 RUS90916.1 - 2.8e-38 131.9 0.0 4.3e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RUS90916.1 - 1.2e-11 44.9 5.0 2.2e-08 34.3 0.5 2.6 2 0 0 2 2 2 2 Enolase, N-terminal domain Ku_PK_bind PF08785.11 RUS90918.1 - 0.26 11.4 4.3 9.9 6.3 0.1 5.0 4 0 0 4 4 4 0 Ku C terminal domain like RVT_1 PF00078.27 RUS90919.1 - 4.1e-25 88.6 0.0 8.8e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 RUS90919.1 - 2.7e-07 31.2 0.6 9.6e-07 29.4 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 RUS90921.1 - 1e-35 123.3 0.0 1.9e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prok-TraM PF09228.10 RUS90922.1 - 0.13 12.6 0.3 30 5.1 0.0 2.5 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Macoilin PF09726.9 RUS90923.1 - 0.96 7.9 18.0 1.1 7.7 18.0 1.1 1 0 0 1 1 1 0 Macoilin family zf-H2C2_2 PF13465.6 RUS90924.1 - 2.1e-24 84.8 48.3 3.9e-06 27.0 0.4 7.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 RUS90924.1 - 3.1e-16 58.8 83.0 0.0004 20.7 2.2 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-met PF12874.7 RUS90924.1 - 0.0027 18.0 54.1 0.68 10.4 2.7 7.1 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS90924.1 - 0.36 11.2 50.7 2.5 8.5 2.4 7.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.7 RUS90925.1 - 6.6e-53 177.2 23.5 5.8e-13 49.2 0.1 5.6 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) MIB_HERC2 PF06701.13 RUS90925.1 - 2.2e-48 162.4 28.5 2.5e-26 91.7 4.5 3.9 4 0 0 4 4 4 2 Mib_herc2 Ank_4 PF13637.6 RUS90925.1 - 7.4e-38 128.5 7.4 2.2e-08 34.5 0.0 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) SH3_15 PF18346.1 RUS90925.1 - 6.2e-37 125.7 14.9 1.2e-21 76.8 0.3 3.7 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank_5 PF13857.6 RUS90925.1 - 6.2e-35 118.8 4.8 1e-07 32.0 0.2 7.2 4 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 RUS90925.1 - 7.8e-33 111.5 11.5 2.8e-05 24.4 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 RUS90925.1 - 1.2e-22 77.5 2.1 0.0032 17.8 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 RUS90925.1 - 2.8e-13 49.5 46.8 8.6e-10 38.3 9.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 RUS90925.1 - 1.9e-09 37.2 7.4 1.9e-09 37.2 7.4 2.9 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-RING_UBOX PF13445.6 RUS90925.1 - 0.0042 17.1 2.7 0.0042 17.1 2.7 4.0 3 0 0 3 3 3 1 RING-type zinc-finger Laminin_G_1 PF00054.23 RUS90926.1 - 0.14 12.3 0.5 0.22 11.7 0.1 1.5 2 0 0 2 2 2 0 Laminin G domain AIP3 PF03915.13 RUS90927.1 - 1.3e-14 54.1 9.7 1.3e-14 54.1 9.7 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 zf-B_box PF00643.24 RUS90927.1 - 4.1e-06 26.9 8.3 4.1e-06 26.9 8.3 4.3 3 1 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 RUS90927.1 - 3.4e-05 23.6 9.5 3.4e-05 23.6 9.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS90927.1 - 5.3e-05 23.1 9.1 5.3e-05 23.1 9.1 3.8 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RUS90927.1 - 8.8e-05 22.4 9.7 8.8e-05 22.4 9.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger DivIVA PF05103.13 RUS90927.1 - 0.003 17.6 0.3 0.003 17.6 0.3 2.8 3 0 0 3 3 3 1 DivIVA protein ATP-gua_Ptrans PF00217.19 RUS90927.1 - 0.0064 16.0 0.1 0.019 14.4 0.1 1.8 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain FUSC PF04632.12 RUS90927.1 - 1.3 7.4 4.9 2.3 6.6 4.9 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.18 RUS90927.1 - 2.4 7.4 11.5 2 7.6 6.6 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SH3BGR PF04908.15 RUS90928.1 - 9e-21 73.9 0.1 1.1e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 RUS90928.1 - 0.032 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Cyclin_N PF00134.23 RUS90929.1 - 1.1e-07 31.6 6.9 8.8e-07 28.7 2.6 3.4 2 1 1 3 3 3 1 Cyclin, N-terminal domain YrpD PF15493.6 RUS90929.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD BORCS6 PF10157.9 RUS90929.1 - 0.042 14.1 0.4 0.093 13.0 0.4 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 LRR_4 PF12799.7 RUS90930.1 - 3.4e-44 148.1 71.4 4.9e-09 36.3 2.7 6.9 1 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RUS90930.1 - 1.1e-25 90.2 13.9 8.6e-11 41.6 8.0 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 RUS90930.1 - 7.5e-24 83.3 61.5 6.3e-07 29.1 7.7 6.2 1 1 6 7 7 7 7 Leucine rich repeat UB2H PF14814.6 RUS90930.1 - 0.005 16.8 1.3 12 6.0 0.0 5.2 4 2 1 6 6 6 1 Bifunctional transglycosylase second domain LRR_1 PF00560.33 RUS90930.1 - 0.019 15.4 30.5 20 6.2 0.1 9.2 8 2 1 9 9 9 0 Leucine Rich Repeat MAS20 PF02064.15 RUS90930.1 - 0.079 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor IGR PF09597.10 RUS90930.1 - 0.092 12.9 0.3 1.4e+02 2.7 0.0 4.4 3 1 2 5 5 5 0 IGR protein motif LRR_6 PF13516.6 RUS90930.1 - 0.16 12.1 0.0 0.16 12.1 0.0 8.9 10 1 1 11 11 11 0 Leucine Rich repeat RVT_1 PF00078.27 RUS90931.1 - 9.1e-07 28.6 0.9 1.5e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plk4_PB2 PF18409.1 RUS90931.1 - 0.034 14.8 1.2 1.7 9.4 0.0 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Ank_4 PF13637.6 RUS90932.1 - 5.8e-26 90.5 5.2 4.1e-13 49.6 0.2 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS90932.1 - 2e-20 72.3 1.6 4.6e-07 30.0 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 RUS90932.1 - 1e-19 70.9 0.0 2.1e-14 53.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS90932.1 - 3.1e-19 68.8 0.3 7.4e-11 42.1 0.3 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS90932.1 - 2.7e-16 58.0 0.2 2.3e-05 24.4 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Lig_chan PF00060.26 RUS90933.1 - 6.9e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 RUS90933.1 - 0.0007 19.1 0.0 0.0044 16.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Cadherin PF00028.17 RUS90935.1 - 5.1e-14 52.5 0.0 2.2e-06 28.0 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 RUS90935.1 - 3.9e-07 30.3 0.0 9.3e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Polysacc_lyase PF14099.6 RUS90935.1 - 0.00026 20.9 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase Cadherin_C_2 PF16492.5 RUS90935.1 - 0.013 16.2 0.0 0.051 14.3 0.0 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PA14 PF07691.12 RUS90935.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 PA14 domain Amnionless PF14828.6 RUS90935.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless Cadherin_3 PF16184.5 RUS90935.1 - 0.13 12.2 0.0 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Cadherin-like LRR_8 PF13855.6 RUS90936.1 - 4.2e-21 74.5 13.6 2e-11 43.5 0.3 4.1 2 1 2 4 4 4 2 Leucine rich repeat Ig_3 PF13927.6 RUS90936.1 - 1.4e-08 35.2 0.0 1.3e-07 32.2 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS90936.1 - 4.5e-08 33.1 0.0 3.7e-06 26.9 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 RUS90936.1 - 5.3e-07 29.9 8.9 2.1e-05 24.8 1.7 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS90936.1 - 7.8e-06 25.9 0.9 2.6e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 RUS90936.1 - 0.00038 20.6 0.0 0.0011 19.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 RUS90936.1 - 0.00072 19.8 9.1 3.8 8.4 0.0 6.2 5 1 0 5 5 5 1 Leucine Rich Repeat Apolipoprotein PF01442.18 RUS90936.1 - 0.0017 18.2 0.9 0.0027 17.6 0.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ig_2 PF13895.6 RUS90936.1 - 0.0019 18.5 0.0 0.34 11.3 0.0 2.9 1 1 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.24 RUS90936.1 - 0.0083 16.6 0.0 0.027 15.0 0.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.6 RUS90936.1 - 0.057 12.9 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Dynamitin PF04912.14 RUS90936.1 - 0.15 11.4 1.5 0.21 10.8 1.5 1.1 1 0 0 1 1 1 0 Dynamitin Activator-TraM PF11657.8 RUS90936.1 - 0.19 11.6 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Cadherin PF00028.17 RUS90937.1 - 5.5e-07 29.9 1.1 0.02 15.3 0.0 3.8 2 1 0 3 3 3 2 Cadherin domain Cadherin_C_2 PF16492.5 RUS90937.1 - 0.0014 19.4 0.0 0.0056 17.4 0.0 2.1 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Cadherin_4 PF17803.1 RUS90937.1 - 0.0021 18.6 1.1 0.0021 18.6 1.1 3.4 3 0 0 3 3 3 1 Bacterial cadherin-like domain EphA2_TM PF14575.6 RUS90937.1 - 0.011 16.5 0.4 0.16 12.9 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_2 PF05510.13 RUS90937.1 - 0.02 13.7 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon YchF-GTPase_C PF06071.13 RUS90937.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) SIT PF15330.6 RUS90937.1 - 0.1 13.1 0.6 0.32 11.4 0.1 2.0 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Big_9 PF17963.1 RUS90937.1 - 5.6 7.8 17.7 0.1 13.4 7.1 3.3 3 0 0 3 3 3 0 Bacterial Ig domain Cadherin PF00028.17 RUS90938.1 - 1.1e-15 57.8 0.4 4.4e-07 30.2 0.1 2.6 2 0 0 2 2 2 2 Cadherin domain HH_signal PF01085.18 RUS90938.1 - 0.17 11.5 1.5 0.37 10.4 1.5 1.5 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain HLH PF00010.26 RUS90940.1 - 2.4e-15 56.2 0.4 7.4e-15 54.6 0.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VCBS PF13517.6 RUS90942.1 - 1.1e-11 45.1 15.2 0.0061 17.1 1.5 5.4 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 RUS90942.1 - 1.7e-07 30.8 0.2 0.0028 17.5 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 RUS90942.1 - 9.7e-06 25.3 0.5 0.0011 18.6 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain FG-GAP PF01839.23 RUS90942.1 - 0.00029 20.9 27.7 0.067 13.3 0.2 6.2 6 0 0 6 6 6 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 RUS90942.1 - 0.0045 16.4 0.9 2.4 7.5 0.0 3.4 3 0 0 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region DUF4589 PF15252.6 RUS90942.1 - 0.36 10.8 1.3 3.9 7.4 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4589) Ependymin PF00811.18 RUS90943.1 - 1.4e-06 28.6 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ependymin zinc_ribbon_4 PF13717.6 RUS90944.1 - 5.9e-11 42.1 21.9 10 6.2 0.1 9.0 1 1 8 9 9 9 9 zinc-ribbon domain Trp_repressor PF01371.19 RUS90944.1 - 1.3e-07 31.6 6.8 19 5.5 0.1 6.8 1 1 8 9 9 9 8 Trp repressor protein LacI PF00356.21 RUS90944.1 - 1e-06 28.4 4.4 13 5.6 0.0 5.5 1 1 7 8 8 8 8 Bacterial regulatory proteins, lacI family DZR PF12773.7 RUS90944.1 - 5e-05 23.2 33.1 1.9 8.6 1.9 3.8 1 1 3 4 4 4 4 Double zinc ribbon RNase_PH_C PF03725.15 RUS90944.1 - 0.0041 17.1 19.2 84 3.3 0.1 8.7 1 1 9 10 10 10 0 3' exoribonuclease family, domain 2 TACI-CRD2 PF09305.10 RUS90944.1 - 0.044 13.8 44.6 29 4.8 0.3 8.9 9 0 0 9 9 9 0 TACI, cysteine-rich domain DUF3006 PF11213.8 RUS90944.1 - 0.053 13.8 1.6 9.8e+02 0.1 0.0 6.2 9 0 0 9 9 9 0 Protein of unknown function (DUF3006) MFS_1 PF07690.16 RUS90945.1 - 2.8e-10 39.7 29.8 2.7e-06 26.6 16.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3493 PF11998.8 RUS90945.1 - 0.0061 16.7 0.3 0.077 13.2 0.1 2.6 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 Pkinase PF00069.25 RUS90946.1 - 1e-16 61.1 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90946.1 - 1.4e-06 27.8 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS90947.1 - 1.5e-15 57.3 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS90947.1 - 0.0029 16.9 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS90947.1 - 0.18 11.0 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like SDA1 PF05285.12 RUS90948.1 - 0.082 12.3 45.4 0.092 12.2 45.4 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 RUS90948.1 - 0.59 9.5 33.4 0.74 9.2 33.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 RUS90948.1 - 0.88 8.3 11.0 0.83 8.4 11.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RUS90949.1 - 1.3 8.2 34.3 2 7.7 34.3 1.2 1 0 0 1 1 1 0 BUD22 Cadherin PF00028.17 RUS90950.1 - 2.5e-39 133.6 0.1 9.6e-17 61.2 0.0 3.3 3 0 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 RUS90950.1 - 2e-14 53.2 0.0 1.4e-10 40.9 0.1 2.4 2 0 0 2 2 2 2 Cadherin-like Cadherin_3 PF16184.5 RUS90950.1 - 0.00052 20.0 0.1 1.9 8.5 0.0 2.8 3 0 0 3 3 3 2 Cadherin-like wnt PF00110.19 RUS90953.1 - 1.2e-117 392.9 22.4 1.4e-117 392.7 22.4 1.0 1 0 0 1 1 1 1 wnt family p450 PF00067.22 RUS90955.1 - 0.00012 21.0 0.0 0.00014 20.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 RUS90956.1 - 1e-53 182.8 0.5 1.5e-52 178.9 0.5 1.9 1 1 0 1 1 1 1 Cytochrome P450 C_tripleX PF02363.19 RUS90957.1 - 4.4 7.8 22.5 1.8e+04 -10.9 22.5 3.7 1 1 0 1 1 1 0 Cysteine rich repeat Tetraspanin PF00335.20 RUS90959.1 - 1.4e-40 139.4 8.8 1.6e-40 139.2 8.8 1.0 1 0 0 1 1 1 1 Tetraspanin family HLH PF00010.26 RUS90960.1 - 1.3e-16 60.3 0.2 2.1e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M10 PF00413.24 RUS90963.1 - 3.5e-40 137.4 1.3 6.7e-40 136.5 0.6 1.8 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.19 RUS90963.1 - 2.6e-16 59.3 24.2 1e-06 28.6 1.0 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 RUS90963.1 - 0.0016 18.6 0.0 0.0063 16.7 0.0 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 RUS90963.1 - 0.0024 17.5 0.0 0.29 10.7 0.1 2.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Metallopep PF12044.8 RUS90963.1 - 0.0047 15.6 0.1 0.0077 14.9 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_4 PF13583.6 RUS90963.1 - 0.0095 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 RUS90963.1 - 0.019 14.2 0.3 0.039 13.2 0.3 1.4 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 RUS90963.1 - 0.043 14.0 1.0 0.097 12.8 1.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 RUS90963.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_3 PF13582.6 RUS90963.1 - 0.26 11.8 2.4 0.63 10.6 2.4 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Transposase_1 PF01359.18 RUS90964.1 - 7.7e-16 57.7 0.0 1.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) DDE_3 PF13358.6 RUS90964.1 - 1.7e-06 27.9 0.0 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SNAP PF14938.6 RUS90966.1 - 0.0016 17.9 5.4 0.003 17.0 2.5 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP ER-remodelling PF14755.6 RUS90966.1 - 0.21 11.8 2.3 0.59 10.4 2.3 1.7 1 0 0 1 1 1 0 Intracellular membrane remodeller EST1 PF10374.9 RUS90966.1 - 0.3 11.7 3.0 1.8 9.2 0.0 3.5 4 1 0 4 4 4 0 Telomerase activating protein Est1 Zn_ribbon_recom PF13408.6 RUS90968.1 - 5.2 7.7 18.8 0.39 11.3 1.9 5.4 5 0 0 5 5 5 0 Recombinase zinc beta ribbon domain SpoIIIAH PF12685.7 RUS90969.1 - 0.0027 17.6 0.7 0.0027 17.6 0.7 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein DUF2828 PF11443.8 RUS90969.1 - 0.036 12.2 0.0 0.049 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SpoIIP PF07454.11 RUS90969.1 - 0.078 12.4 11.5 0.14 11.5 11.5 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4820 PF16091.5 RUS90969.1 - 0.12 11.7 5.9 0.3 10.4 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CLN3 PF02487.17 RUS90969.1 - 0.16 10.9 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein Nop14 PF04147.12 RUS90969.1 - 0.17 10.0 31.1 0.26 9.4 31.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RUS90969.1 - 0.56 9.1 6.2 0.93 8.4 6.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 RUS90969.1 - 0.87 7.4 6.9 1.1 7.1 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 RUS90969.1 - 1.2 8.8 10.5 2.6 7.7 10.4 1.6 1 1 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 RUS90969.1 - 1.8 6.5 34.4 2.6 6.0 34.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RAB3GAP2_C PF14656.6 RUS90969.1 - 1.9 6.6 6.8 2.7 6.1 6.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus TRAP_alpha PF03896.16 RUS90969.1 - 2 7.5 16.8 0.13 11.5 11.6 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AAA_11 PF13086.6 RUS90969.1 - 2.1 8.0 5.6 3.5 7.3 5.6 1.3 1 0 0 1 1 1 0 AAA domain AIF_C PF14721.6 RUS90969.1 - 6.9 7.0 12.4 0.069 13.5 4.0 1.9 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_M22 PF00814.25 RUS90970.1 - 1.6e-67 228.1 0.0 1.9e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Asn_synthase PF00733.21 RUS90971.1 - 3.7e-79 266.9 0.3 2.4e-48 165.6 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 RUS90971.1 - 2.4e-25 88.8 0.0 4.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RUS90971.1 - 4.7e-20 72.2 0.0 1e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 RUS90971.1 - 1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 RUS90971.1 - 0.00018 21.1 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 RUS90971.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 RUS90971.1 - 0.053 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase RIH_assoc PF08454.11 RUS90972.1 - 3.7e-22 78.1 11.9 1.1e-18 66.9 2.0 4.9 4 1 0 4 4 4 2 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 RUS90972.1 - 1.2e-19 70.5 0.9 1.2e-19 70.5 0.9 3.9 3 1 0 3 3 3 2 RIH domain Ins145_P3_rec PF08709.11 RUS90972.1 - 2.2e-18 66.2 1.6 1.1e-16 60.8 0.1 3.3 4 0 0 4 4 4 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 RUS90972.1 - 1.1e-17 64.4 4.8 3.5e-14 53.1 1.0 3.0 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 RUS90972.1 - 1.8e-07 30.7 8.9 3.8e-07 29.6 8.9 1.5 1 0 0 1 1 1 1 Ion transport protein SDA1 PF05285.12 RUS90973.1 - 0.00076 19.0 29.0 0.00076 19.0 29.0 2.2 2 0 0 2 2 2 1 SDA1 DNA_pol_phi PF04931.13 RUS90974.1 - 0.00032 19.0 27.4 0.0004 18.7 27.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 RUS90974.1 - 0.033 13.5 11.9 0.04 13.2 11.9 1.2 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 RUS90974.1 - 0.055 13.3 1.0 0.065 13.1 1.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 RUS90974.1 - 0.26 9.5 21.7 0.43 8.7 21.7 1.3 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RUS90974.1 - 0.48 8.7 3.8 0.54 8.5 3.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 RUS90974.1 - 1.1 8.5 37.3 2.3 7.5 37.3 1.5 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RUS90974.1 - 8.6 6.2 21.8 17 5.2 21.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Guanylate_cyc PF00211.20 RUS90975.1 - 3.7e-27 95.1 0.5 9.8e-21 74.2 0.0 2.5 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NIT PF08376.10 RUS90975.1 - 2.4e-22 80.6 0.0 3.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing HNOBA PF07701.14 RUS90975.1 - 6.4e-06 25.8 0.1 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pro_sub2 PF18513.1 RUS90975.1 - 0.037 14.2 3.0 0.24 11.6 0.3 2.7 2 0 0 2 2 2 0 Prodomain subtilisin 2 CBM_14 PF01607.24 RUS90977.1 - 1.1e-07 31.9 1.9 2.5e-07 30.7 1.9 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF1980 PF09323.10 RUS90980.1 - 0.053 13.4 0.2 0.053 13.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4586 PF15239.6 RUS90981.1 - 0.06 13.5 0.2 0.091 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) Carn_acyltransf PF00755.20 RUS90982.1 - 9.3e-172 572.7 0.0 1e-171 572.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Lamprin PF06403.11 RUS90984.1 - 2.4e-08 34.0 0.0 0.3 11.0 0.0 3.8 1 1 2 3 3 3 3 Lamprin Keratin_B2_2 PF13885.6 RUS90984.1 - 0.02 14.9 31.2 1.8e+04 -11.3 31.2 3.6 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Pentapeptide PF00805.22 RUS90984.1 - 0.03 14.0 8.8 4 7.2 0.2 4.0 3 1 1 4 4 4 0 Pentapeptide repeats (8 copies) 7tm_2 PF00002.24 RUS90985.1 - 3.3e-23 82.2 12.2 4.4e-23 81.8 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 RUS90985.1 - 0.0016 17.9 7.7 0.0025 17.2 7.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1418 PF07214.12 RUS90985.1 - 0.38 10.7 1.5 4.7 7.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Lipase PF00151.19 RUS90987.1 - 4.3e-19 69.0 0.1 6.1e-14 52.1 0.0 2.4 1 1 1 2 2 2 2 Lipase C1_1 PF00130.22 RUS90989.1 - 0.0096 15.8 0.4 0.029 14.2 0.4 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SWIM PF04434.17 RUS90989.1 - 0.01 15.5 0.2 0.026 14.2 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger PHD_4 PF16866.5 RUS90989.1 - 0.011 15.8 0.9 0.03 14.4 0.9 1.8 1 0 0 1 1 1 0 PHD-finger PHD PF00628.29 RUS90989.1 - 0.085 12.8 3.0 0.28 11.1 3.0 2.0 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.19 RUS90989.1 - 0.11 12.4 2.3 0.24 11.4 2.3 1.6 1 0 0 1 1 1 0 AT hook motif Zf_RING PF16744.5 RUS90989.1 - 0.14 12.3 3.2 0.43 10.7 3.2 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger 7tm_2 PF00002.24 RUS90990.1 - 1.8e-38 132.2 18.2 2.5e-38 131.8 18.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS90990.1 - 1.4e-12 47.9 4.2 4.5e-12 46.3 4.2 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PT PF04886.12 RUS90990.1 - 0.017 14.7 35.2 0.22 11.1 10.2 3.8 2 1 0 2 2 2 0 PT repeat Cornifin PF02389.15 RUS90990.1 - 0.29 11.3 8.2 0.63 10.2 8.2 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF4774 PF15999.5 RUS90990.1 - 0.34 10.8 2.0 6.8 6.6 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4774) DUF1997 PF09366.10 RUS90990.1 - 0.71 10.0 2.3 41 4.3 2.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1997) CBM_14 PF01607.24 RUS90991.1 - 3.7e-23 81.4 17.0 7.6e-08 32.4 1.0 3.7 2 1 1 3 3 3 3 Chitin binding Peritrophin-A domain I-set PF07679.16 RUS90991.1 - 0.0071 16.4 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Metallothio_Cad PF07846.11 RUS90991.1 - 0.057 13.5 1.7 0.14 12.3 1.7 1.7 1 0 0 1 1 1 0 Metallothionein family Ig_3 PF13927.6 RUS90991.1 - 1.4 9.6 5.1 5.8 7.6 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin domain DUF1676 PF07898.13 RUS90992.1 - 0.079 13.0 2.2 0.087 12.9 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Mst1_SARAH PF11629.8 RUS90992.1 - 0.48 10.5 2.4 0.45 10.6 0.3 1.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 SSF PF00474.17 RUS90993.1 - 3.4e-44 151.4 23.6 3.4e-44 151.4 23.6 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family Homeodomain PF00046.29 RUS90994.1 - 7.4e-09 35.3 1.8 1.1e-08 34.8 1.8 1.3 1 0 0 1 1 1 1 Homeodomain Fasciclin PF02469.22 RUS90995.1 - 1.9e-63 212.4 0.0 3.8e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain VHP PF02209.19 RUS90995.1 - 0.26 11.4 0.0 0.47 10.6 0.0 1.4 1 0 0 1 1 1 0 Villin headpiece domain TLD PF07534.16 RUS90996.1 - 2.8e-29 102.1 0.3 6e-29 101.1 0.3 1.6 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 RUS90996.1 - 3.2e-15 56.4 0.6 4.7e-15 55.8 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pyr_redox_2 PF07992.14 RUS90998.1 - 1.6e-64 218.0 1.5 2.7e-64 217.2 1.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RUS90998.1 - 2.9e-33 114.4 0.3 8.7e-33 112.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RUS90998.1 - 1.2e-18 67.4 4.0 1.3e-17 64.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS90998.1 - 2.8e-18 66.2 0.5 5.7e-18 65.2 0.5 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RUS90998.1 - 0.00065 18.9 0.0 0.0022 17.2 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 RUS90998.1 - 0.00085 18.7 0.6 0.36 10.1 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 RUS90998.1 - 0.003 16.7 4.1 0.026 13.6 1.1 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 RUS90998.1 - 0.0048 15.7 8.1 0.4 9.3 0.0 3.4 4 0 0 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 RUS90998.1 - 0.0085 15.5 4.0 0.01 15.3 2.8 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 RUS90998.1 - 0.019 14.9 3.6 0.11 12.4 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 RUS90998.1 - 0.026 13.8 0.2 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 RUS90998.1 - 0.051 12.9 1.0 4.6 6.6 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 RUS90998.1 - 0.098 13.1 0.2 21 5.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 RUS90998.1 - 0.13 12.5 0.4 0.33 11.2 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 RUS90998.1 - 0.17 11.0 7.9 1.5 7.8 5.0 3.0 2 1 0 2 2 2 0 Glucose inhibited division protein A EF-hand_6 PF13405.6 RUS91000.1 - 6.3e-11 41.3 1.7 0.065 13.2 0.0 6.4 6 1 1 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 RUS91000.1 - 2.4e-07 31.1 4.2 0.0015 18.9 0.0 4.3 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS91000.1 - 5.9e-07 28.6 3.9 1.2 8.8 0.0 5.8 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 RUS91000.1 - 0.00034 20.4 0.0 4.5 7.2 0.0 5.1 6 1 0 6 6 6 1 EF-hand domain pair DUF1870 PF08965.10 RUS91000.1 - 0.025 14.6 0.0 3.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) WD40 PF00400.32 RUS91003.1 - 5.4e-13 49.2 1.7 0.00023 21.9 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91003.1 - 0.053 13.8 0.0 0.98 9.8 0.0 2.7 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Rhomboid PF01694.22 RUS91004.1 - 2.2e-31 108.9 10.2 2.2e-31 108.9 10.2 2.4 2 1 1 3 3 3 1 Rhomboid family DUF4191 PF13829.6 RUS91004.1 - 1.9 7.8 3.8 1.5 8.1 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) GtrA PF04138.14 RUS91004.1 - 2.1 8.6 10.3 0.17 12.1 5.0 1.9 2 0 0 2 2 2 0 GtrA-like protein Na_Ca_ex PF01699.24 RUS91007.1 - 1.3e-43 148.6 19.8 9.9e-27 93.8 9.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 RUS91007.1 - 5e-32 110.0 1.8 1.3e-16 60.6 0.1 2.7 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex_C PF16494.5 RUS91007.1 - 0.019 15.4 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Pkinase PF00069.25 RUS91009.1 - 3e-29 102.2 0.0 3.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91009.1 - 1.3e-17 63.9 0.0 1.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS91009.1 - 4.4e-09 35.6 0.1 6.4e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RUS91009.1 - 0.00057 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RUS91009.1 - 0.029 13.4 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RUS91009.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SF1-HH PF16275.5 RUS91010.1 - 1.2e-42 144.8 3.7 1.2e-42 144.8 3.7 2.8 4 0 0 4 4 4 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 RUS91010.1 - 2.4e-08 33.7 0.2 5.9e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 RUS91010.1 - 0.0002 21.3 0.5 0.0003 20.7 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle AMP-binding PF00501.28 RUS91011.1 - 2.3e-82 276.9 0.0 3e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RUS91011.1 - 0.00015 22.6 0.0 0.00041 21.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_1 PF00001.21 RUS91012.1 - 9.8e-47 159.5 19.9 9.8e-47 159.5 19.9 1.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91012.1 - 1.1e-05 25.0 15.3 0.0067 15.8 0.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 RUS91012.1 - 0.08 12.3 21.4 0.29 10.4 15.6 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 RUS91012.1 - 0.22 11.1 15.5 0.033 13.8 10.9 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx RT_RNaseH PF17917.1 RUS91013.1 - 1.3e-32 112.2 0.0 4.5e-32 110.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 RUS91013.1 - 5.2e-24 84.2 0.0 1.4e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 RUS91013.1 - 1.8e-20 73.3 0.1 3.8e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS91013.1 - 7.9e-16 57.9 0.3 2.5e-15 56.3 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 RUS91013.1 - 8.5e-09 35.5 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 RUS91013.1 - 1.2e-05 25.0 0.0 4.7e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain YebO PF13974.6 RUS91013.1 - 0.29 11.2 2.1 0.66 10.1 2.1 1.5 1 0 0 1 1 1 0 YebO-like protein Ependymin PF00811.18 RUS91014.1 - 1.2e-05 25.5 0.1 2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Ependymin U-box PF04564.15 RUS91015.1 - 1.4e-29 102.1 0.7 2.5e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain TPR_1 PF00515.28 RUS91015.1 - 1.7e-21 75.1 2.0 7.9e-08 31.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RUS91015.1 - 9.8e-19 65.9 2.0 2.3e-06 27.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 RUS91015.1 - 6.9e-14 52.4 0.7 1.4e-13 51.4 0.7 1.6 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 RUS91015.1 - 6.1e-12 45.0 0.1 1.9e-05 24.3 0.1 3.4 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.6 RUS91015.1 - 3.2e-10 40.1 3.6 3.1e-06 27.4 0.7 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RUS91015.1 - 9.6e-10 37.8 2.5 0.11 12.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS91015.1 - 1.6e-09 38.2 0.2 3e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS91015.1 - 2.5e-08 34.0 2.0 4.4e-08 33.2 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RUS91015.1 - 9.8e-07 29.1 1.2 0.7 10.9 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS91015.1 - 2.1e-06 28.1 0.8 0.00014 22.3 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91015.1 - 2.6e-06 27.2 0.9 2.9 8.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS91015.1 - 1.2e-05 25.6 4.5 1.5 9.6 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 RUS91015.1 - 0.00014 22.0 0.0 0.00036 20.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_17 PF13431.6 RUS91015.1 - 0.00015 21.9 2.8 0.0014 18.8 0.2 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RUS91015.1 - 0.00025 21.1 0.5 0.00059 19.9 0.1 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 RUS91015.1 - 0.0047 17.1 1.7 0.031 14.5 0.1 2.4 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 Coatomer_E PF04733.14 RUS91015.1 - 0.0058 16.1 0.2 0.04 13.3 0.0 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit DNA_meth_N PF18284.1 RUS91015.1 - 0.039 13.8 0.0 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 DNA methylase N-terminal domain Fis1_TPR_C PF14853.6 RUS91015.1 - 0.063 13.4 0.2 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 RUS91015.1 - 0.07 13.2 0.2 1.1 9.3 0.1 2.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 RUS91015.1 - 0.094 12.6 5.5 6.5 6.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat G_glu_transpept PF01019.21 RUS91016.1 - 4.8e-143 477.6 0.0 5.6e-143 477.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_hydro_38N PF01074.22 RUS91017.1 - 1e-65 222.0 0.0 1.6e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 RUS91017.1 - 6.2e-35 121.2 0.0 9.6e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 RUS91017.1 - 1e-06 28.7 0.1 3.3e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Alpha-mann_mid PF09261.11 RUS91017.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Alpha mannosidase middle domain Ribosomal_S24e PF01282.19 RUS91018.1 - 1.2e-39 134.1 0.0 2.2e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Trypsin PF00089.26 RUS91020.1 - 1.5e-46 159.0 1.7 5.2e-46 157.2 1.7 1.7 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.11 RUS91020.1 - 1.2e-08 35.3 0.3 2e-08 34.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 RUS91020.1 - 0.00071 20.5 0.0 0.00099 20.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ephrin_rec_like PF07699.13 RUS91021.1 - 1.2e-126 412.4 292.9 1.2e-09 37.7 11.1 24.4 22 2 1 23 23 23 20 Putative ephrin-receptor like EGF PF00008.27 RUS91021.1 - 1.1e-43 147.0 261.4 2.3e-08 34.2 10.7 21.3 20 0 0 20 20 20 13 EGF-like domain hEGF PF12661.7 RUS91021.1 - 5.5e-17 61.7 210.8 2.8e-05 24.6 1.8 22.5 21 0 0 21 21 21 10 Human growth factor-like EGF Laminin_G_3 PF13385.6 RUS91021.1 - 5.5e-05 23.4 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.13 RUS91021.1 - 0.00058 20.2 7.5 0.00058 20.2 7.5 20.0 19 0 0 19 19 19 9 EGF-like domain EGF_3 PF12947.7 RUS91021.1 - 0.002 18.3 4.9 0.002 18.3 4.9 19.5 16 1 1 17 17 17 6 EGF domain DUF2706 PF10913.8 RUS91021.1 - 0.0037 17.1 0.1 0.024 14.4 0.1 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2706) TMEM51 PF15345.6 RUS91021.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Sushi PF00084.20 RUS91022.1 - 3.6e-32 110.7 44.8 7.6e-09 36.0 0.4 9.9 9 1 1 10 10 10 6 Sushi repeat (SCR repeat) EGF_CA PF07645.15 RUS91022.1 - 1.2e-12 47.8 35.7 1.5e-07 31.5 5.0 5.4 5 0 0 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS91022.1 - 4.1e-08 33.4 26.5 0.00055 20.2 3.9 5.4 5 1 1 6 6 6 3 Coagulation Factor Xa inhibitory site HYR PF02494.16 RUS91022.1 - 5.9e-08 32.9 8.0 3.2e-05 24.2 2.0 3.5 3 1 0 3 3 3 2 HYR domain cEGF PF12662.7 RUS91022.1 - 2.5e-07 30.5 35.3 1.3e-06 28.2 1.9 8.1 8 0 0 8 8 8 2 Complement Clr-like EGF-like EGF PF00008.27 RUS91022.1 - 0.0038 17.5 4.7 0.0038 17.5 4.7 5.3 6 0 0 6 6 6 2 EGF-like domain EGF_3 PF12947.7 RUS91022.1 - 0.0038 17.4 27.0 0.093 13.0 3.0 5.3 4 0 0 4 4 4 2 EGF domain hEGF PF12661.7 RUS91022.1 - 0.0045 17.6 1.5 0.0045 17.6 1.5 6.5 5 1 0 5 5 5 2 Human growth factor-like EGF Big_3_4 PF13754.6 RUS91022.1 - 0.043 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function CUB PF00431.20 RUS91023.1 - 7.5e-24 84.2 0.0 2.7e-12 47.0 0.0 3.3 3 0 0 3 3 3 3 CUB domain Sushi PF00084.20 RUS91023.1 - 2.4e-10 40.8 11.0 8.2e-10 39.1 1.3 3.4 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Ldl_recept_a PF00057.18 RUS91023.1 - 1.6e-09 37.8 10.5 3.7e-09 36.6 10.5 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A CUB_2 PF02408.20 RUS91023.1 - 6.2e-05 22.7 0.1 0.0029 17.3 0.0 2.7 2 1 0 2 2 2 1 CUB-like domain Gal-3-0_sulfotr PF06990.11 RUS91024.1 - 1.3e-46 159.3 3.1 9.5e-45 153.2 3.5 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 RUS91024.1 - 1.6e-07 31.5 1.4 2.7e-07 30.7 1.4 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF5372 PF17342.2 RUS91024.1 - 0.016 15.6 0.0 3.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Rtt106_N PF18215.1 RUS91024.1 - 0.034 13.9 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain WD40 PF00400.32 RUS91025.1 - 6.4e-11 42.6 1.2 1.7 9.6 0.0 8.1 9 0 0 9 9 9 2 WD domain, G-beta repeat Nup160 PF11715.8 RUS91025.1 - 0.00056 18.7 0.2 0.16 10.6 0.0 2.7 2 0 0 2 2 2 2 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 RUS91025.1 - 0.0025 18.2 0.7 0.0072 16.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS91025.1 - 0.022 14.6 0.0 0.073 12.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair ANAPC4_WD40 PF12894.7 RUS91025.1 - 0.031 14.6 0.0 2.3 8.6 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RUS91025.1 - 0.093 11.5 0.0 7.3 5.2 0.0 3.2 3 0 0 3 3 3 0 Nup133 N terminal like UPF0258 PF06789.12 RUS91026.1 - 0.058 13.5 0.3 3.3 7.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Barstar PF01337.18 RUS91026.1 - 0.15 12.1 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) HR1 PF02185.16 RUS91026.1 - 2 8.6 6.6 0.51 10.5 0.1 2.8 2 1 0 2 2 2 0 Hr1 repeat Carn_acyltransf PF00755.20 RUS91027.1 - 9.9e-177 589.1 0.0 1.2e-176 588.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SR-25 PF10500.9 RUS91027.1 - 0.055 13.1 6.8 0.094 12.3 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 RUS91028.1 - 3e-08 33.5 1.5 0.0013 18.3 0.0 2.7 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 RUS91028.1 - 0.0067 15.8 24.0 0.0067 15.8 24.0 1.7 2 0 0 2 2 2 1 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 RUS91028.1 - 0.1 12.9 20.5 0.15 12.3 20.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 RUS91028.1 - 0.2 11.2 15.4 0.25 10.9 15.4 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 RUS91028.1 - 0.68 9.9 18.1 0.69 9.8 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 RUS91028.1 - 1.4 8.2 19.3 1.6 8.0 19.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RUS91028.1 - 1.6 6.8 22.2 1.9 6.6 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RUS91028.1 - 1.6 7.9 13.9 1.9 7.7 13.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2076 PF09849.9 RUS91028.1 - 2.1 8.3 17.5 2.5 8.1 17.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRN3 PF05327.11 RUS91028.1 - 3.5 6.0 17.0 4.3 5.8 17.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MFS_1 PF07690.16 RUS91029.1 - 5.9e-41 140.6 26.8 2.8e-37 128.5 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 RUS91029.1 - 5.5e-05 22.3 0.7 0.0001 21.5 0.7 1.4 1 0 0 1 1 1 1 PUCC protein Sigma_reg_N PF13800.6 RUS91029.1 - 0.1 12.9 0.3 0.37 11.1 0.3 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MFS_3 PF05977.13 RUS91029.1 - 0.74 8.1 12.0 0.09 11.1 1.1 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector Myb_DNA-bind_5 PF13873.6 RUS91030.1 - 0.035 14.2 2.2 0.86 9.7 0.6 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain FWWh PF14922.6 RUS91031.1 - 3.1e-49 166.7 2.7 5.6e-49 165.8 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function NopRA1 PF16201.5 RUS91032.1 - 3.1e-23 82.4 0.8 4.9e-23 81.8 0.2 1.6 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 RUS91033.1 - 1.5e-23 83.7 0.3 4.7e-23 82.1 0.1 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Npa1 PF11707.8 RUS91034.1 - 3.7e-22 79.2 7.9 3.7e-22 79.2 7.9 1.4 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal ING PF12998.7 RUS91036.1 - 4.2e-29 101.1 2.6 7.4e-29 100.3 2.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RUS91036.1 - 9.6e-07 28.6 8.1 1.7e-06 27.8 8.1 1.4 1 0 0 1 1 1 1 PHD-finger RecG_N PF17190.4 RUS91036.1 - 0.027 15.2 0.7 0.027 15.2 0.7 2.1 2 0 0 2 2 2 0 RecG N-terminal helical domain zf-HC5HC2H PF13771.6 RUS91036.1 - 0.037 14.3 1.0 0.094 13.0 1.0 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF3450 PF11932.8 RUS91036.1 - 0.037 13.3 2.0 0.059 12.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-FPG_IleRS PF06827.14 RUS91036.1 - 0.04 13.8 0.1 0.099 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF1376 PF07120.11 RUS91036.1 - 0.066 13.5 0.4 0.45 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) FlxA PF14282.6 RUS91036.1 - 0.31 11.1 3.7 0.3 11.1 1.9 1.9 1 1 1 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 RUS91036.1 - 0.33 11.2 4.5 0.33 11.2 0.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-RING-like PF08746.11 RUS91036.1 - 0.34 11.2 2.4 0.59 10.5 2.4 1.4 1 0 0 1 1 1 0 RING-like domain PHM7_cyt PF14703.6 RUS91036.1 - 2.1 8.6 6.9 0.11 12.7 0.4 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-C4pol PF14260.6 RUS91036.1 - 2.6 8.6 8.6 0.56 10.7 0.6 2.9 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta YlqD PF11068.8 RUS91036.1 - 2.7 8.4 6.8 5.5 7.4 1.0 2.2 1 1 0 2 2 2 0 YlqD protein Mlf1IP PF10248.9 RUS91038.1 - 1.4e-56 191.2 11.7 2.4e-56 190.4 11.7 1.4 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Proteasome PF00227.26 RUS91039.1 - 1.6e-43 148.4 0.4 1.9e-43 148.2 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit adh_short PF00106.25 RUS91040.1 - 1.1e-27 96.7 0.0 1.4e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS91040.1 - 1.9e-18 66.9 0.0 2.3e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pep_M12B_propep PF01562.19 RUS91040.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide adh_short PF00106.25 RUS91041.1 - 3e-40 137.8 0.2 3.9e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS91041.1 - 1.4e-21 77.2 0.1 1.7e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS91041.1 - 1.6e-06 28.1 0.6 4.2e-06 26.8 0.6 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 RUS91041.1 - 0.0016 17.8 0.8 0.0033 16.7 0.8 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 RUS91041.1 - 0.003 17.5 0.4 0.0044 16.9 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RUS91041.1 - 0.013 14.9 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 RUS91041.1 - 0.031 13.4 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 RUS91041.1 - 0.033 14.3 0.2 0.07 13.2 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 RUS91041.1 - 0.037 13.5 0.3 0.15 11.5 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 RUS91041.1 - 0.044 13.0 0.2 0.065 12.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_replicase_B PF03431.13 RUS91041.1 - 0.047 12.2 0.1 0.062 11.8 0.1 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain DUF2431 PF10354.9 RUS91041.1 - 0.059 13.6 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) Eno-Rase_NADH_b PF12242.8 RUS91041.1 - 0.079 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 RUS91041.1 - 0.083 13.3 0.3 0.21 12.0 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF4431 PF14485.6 RUS91041.1 - 0.092 12.6 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) 7TM_GPCR_Srx PF10328.9 RUS91042.1 - 1.1e-07 31.8 43.8 1.3e-06 28.3 17.3 3.5 1 1 2 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS91042.1 - 9.2e-07 28.4 40.8 0.00019 20.8 9.3 3.1 1 1 2 3 3 3 3 7 transmembrane receptor (rhodopsin family) YjcZ_2 PF09680.10 RUS91042.1 - 0.0056 16.3 5.2 1.4 8.6 0.5 3.0 2 0 0 2 2 2 2 Family of unknown function DUF1772 PF08592.11 RUS91042.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Srg PF02118.21 RUS91042.1 - 0.63 9.6 48.6 0.42 10.2 19.9 3.6 1 1 2 3 3 3 0 Srg family chemoreceptor Peptidase_M13_N PF05649.13 RUS91043.1 - 2.6e-119 399.3 0.7 3.6e-119 398.9 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 RUS91043.1 - 1.4e-80 269.8 0.0 2.4e-79 265.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M13 Baculo_11_kDa PF06143.11 RUS91043.1 - 0.079 12.5 1.3 0.24 11.0 1.3 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family IQCJ-SCHIP1 PF15157.6 RUS91043.1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Sfi1 PF08457.10 RUS91045.1 - 3.4e-08 32.5 106.4 0.00065 18.4 10.1 6.7 2 2 4 6 6 6 6 Sfi1 spindle body protein Sfi1 PF08457.10 RUS91046.1 - 0.00023 19.9 14.4 0.00087 17.9 13.6 1.9 1 1 0 1 1 1 1 Sfi1 spindle body protein TFIIA PF03153.13 RUS91047.1 - 0.006 16.6 12.1 0.006 16.6 12.1 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RUS91047.1 - 0.027 14.1 17.0 0.041 13.5 17.0 1.3 1 0 0 1 1 1 0 Spt20 family FAM83 PF07894.12 RUS91047.1 - 0.033 13.7 4.3 0.053 13.1 4.3 1.3 1 0 0 1 1 1 0 FAM83 A-H DUF4407 PF14362.6 RUS91047.1 - 0.073 12.4 1.6 0.1 11.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 RUS91047.1 - 0.29 11.1 7.1 1.3 8.9 4.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Herpes_Helicase PF02689.14 RUS91047.1 - 0.41 8.5 2.7 0.58 8.0 0.1 1.9 2 0 0 2 2 2 0 Helicase Med3 PF11593.8 RUS91047.1 - 1.2 8.3 14.4 0.99 8.5 12.4 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 RUS91047.1 - 2.2 9.3 4.8 5.4 8.0 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 RUS91047.1 - 3 6.8 8.4 4.6 6.2 8.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PAT1 PF09770.9 RUS91047.1 - 3.3 5.9 19.6 4.3 5.5 19.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMC PF07810.13 RUS91049.1 - 2.7e-15 56.9 1.7 2.7e-15 56.9 1.7 2.2 2 0 0 2 2 2 1 TMC domain Voltage_CLC PF00654.20 RUS91050.1 - 4.5e-78 263.0 25.5 4.5e-78 263.0 25.5 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel ABC_trans_CmpB PF06541.11 RUS91050.1 - 0.003 17.8 2.8 0.003 17.8 2.8 2.6 3 1 0 3 3 3 1 Putative ABC-transporter type IV CBS PF00571.28 RUS91050.1 - 0.037 14.5 0.1 14 6.3 0.0 2.5 2 0 0 2 2 2 0 CBS domain Ank_2 PF12796.7 RUS91055.1 - 1.1e-14 54.8 0.1 2.3e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91055.1 - 3.7e-12 46.5 0.0 5.8e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 RUS91055.1 - 3.8e-11 43.0 0.1 2.1e-06 27.9 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91055.1 - 4.7e-10 38.8 0.0 0.027 15.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RUS91055.1 - 3.1e-09 36.9 0.0 0.00032 21.0 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Fn_bind PF02986.14 RUS91055.1 - 2.5 7.9 6.3 17 5.2 0.1 3.6 3 0 0 3 3 3 0 Fibronectin binding repeat FHA PF00498.26 RUS91056.1 - 2e-14 53.7 0.0 5.5e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RUS91056.1 - 6.3e-06 26.4 0.1 8.1e-05 22.9 0.0 3.0 2 1 1 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Spc29 PF17082.5 RUS91056.1 - 0.0059 16.5 2.7 0.0059 16.5 2.7 6.9 4 3 2 6 6 6 2 Spindle Pole Component 29 DivIC PF04977.15 RUS91056.1 - 0.014 15.2 0.1 0.014 15.2 0.1 15.9 12 4 4 17 17 17 0 Septum formation initiator Tmem26 PF09772.9 RUS91057.1 - 1.3e-95 320.1 6.7 1.7e-95 319.7 6.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.6 RUS91057.1 - 0.038 13.8 5.0 0.1 12.4 2.2 2.3 2 0 0 2 2 2 0 CECR6/TMEM121 family UPF0093 PF03653.13 RUS91057.1 - 0.096 12.9 0.2 0.096 12.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) TMEM154 PF15102.6 RUS91057.1 - 0.46 10.4 3.7 0.24 11.3 0.4 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF2818 PF10993.8 RUS91057.1 - 1.6 9.4 6.5 3.9 8.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) GRP PF07172.11 RUS91057.1 - 4 8.2 14.5 2.3e+02 2.6 14.5 2.6 1 1 0 1 1 1 0 Glycine rich protein family Glyco_hydro_9 PF00759.19 RUS91059.1 - 2e-100 337.1 6.2 3e-64 218.0 2.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 CBM_2 PF00553.19 RUS91059.1 - 5.9e-20 71.5 0.0 3.5e-09 36.9 0.0 3.9 3 0 0 3 3 3 3 Cellulose binding domain UPF1_Zn_bind PF09416.10 RUS91060.1 - 9e-07 29.0 0.0 11 6.0 0.0 6.0 1 1 9 10 10 10 2 RNA helicase (UPF2 interacting domain) BAT PF15915.5 RUS91060.1 - 2.4e-05 24.3 7.0 2.9 7.8 0.9 4.3 1 1 2 4 4 4 4 GAF and HTH_10 associated domain Retrotran_gag_2 PF14223.6 RUS91060.1 - 0.32 10.6 13.0 21 4.8 0.5 5.4 1 1 8 9 9 9 0 gag-polypeptide of LTR copia-type DUF1541 PF07563.11 RUS91060.1 - 0.38 10.7 26.4 15 5.5 0.4 7.9 2 1 10 12 12 12 0 Protein of unknown function (DUF1541) MIF4G PF02854.19 RUS91062.1 - 1.2e-41 142.8 5.4 2.6e-41 141.6 5.4 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 RUS91062.1 - 1.1e-18 67.3 0.5 8e-17 61.3 0.1 3.3 3 0 0 3 3 3 1 MA3 domain W2 PF02020.18 RUS91062.1 - 2.8e-12 46.6 0.1 6.2e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon CNOT1_CAF1_bind PF16415.5 RUS91062.1 - 0.0066 15.9 0.3 0.53 9.6 0.0 2.3 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain rve PF00665.26 RUS91064.1 - 5.6e-23 81.4 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS91064.1 - 6.8e-19 67.7 0.2 1.7e-18 66.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 RUS91064.1 - 1.1e-07 31.6 0.3 2.8e-06 27.0 0.2 2.5 2 0 0 2 2 2 1 Integrase core domain OmpH PF03938.14 RUS91064.1 - 0.12 12.8 4.6 0.25 11.7 4.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 RUS91064.1 - 0.65 10.7 4.8 4.7 7.9 0.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 RUS91064.1 - 1.2 9.3 9.5 0.51 10.5 0.3 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF4164 PF13747.6 RUS91064.1 - 1.7 8.9 7.4 4.9 7.5 1.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ZapB PF06005.12 RUS91064.1 - 6.1 7.4 10.8 0.71 10.3 1.2 2.9 2 1 1 3 3 3 0 Cell division protein ZapB ABC_membrane PF00664.23 RUS91065.1 - 2.9e-39 135.4 2.4 3.5e-39 135.1 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region UPF0093 PF03653.13 RUS91065.1 - 0.039 14.2 3.1 0.077 13.2 0.3 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0093) FtsX PF02687.21 RUS91065.1 - 7.6 7.1 7.8 0.72 10.4 0.2 2.8 2 1 1 3 3 3 0 FtsX-like permease family DUF4672 PF15716.5 RUS91066.1 - 0.11 12.1 0.4 0.19 11.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) ABC_tran PF00005.27 RUS91067.1 - 2.3e-44 151.3 0.4 2.1e-23 83.4 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 RUS91067.1 - 2.7e-41 142.0 11.2 4.1e-41 141.4 11.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 RUS91067.1 - 1e-06 29.2 0.1 0.064 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 RUS91067.1 - 4.6e-06 26.7 0.3 0.067 13.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RUS91067.1 - 4.9e-06 26.2 0.6 0.051 13.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RUS91067.1 - 7.9e-06 25.9 0.3 0.019 15.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 RUS91067.1 - 8.6e-06 25.3 0.5 0.72 9.2 0.1 3.3 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RUS91067.1 - 3.2e-05 23.9 1.7 0.24 11.3 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 RUS91067.1 - 0.00035 20.9 0.1 0.98 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 RUS91067.1 - 0.0022 18.0 3.7 0.31 11.1 0.1 3.0 4 0 0 4 4 3 2 Dynamin family DUF815 PF05673.13 RUS91067.1 - 0.0071 15.5 0.1 0.099 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 RUS91067.1 - 0.013 14.9 0.4 3.1 7.1 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 RUS91067.1 - 0.014 15.9 3.8 0.81 10.2 0.2 3.4 3 1 1 4 4 4 0 AAA domain cobW PF02492.19 RUS91067.1 - 0.014 15.0 1.2 2 8.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 RUS91067.1 - 0.019 15.1 4.3 0.25 11.4 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 RUS91067.1 - 0.023 14.2 0.3 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 RUS91067.1 - 0.045 12.8 0.1 7.8 5.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 RUS91067.1 - 0.053 13.9 0.1 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 RUS91067.1 - 0.059 13.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RUS91067.1 - 0.071 13.0 0.6 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 RUS91067.1 - 0.076 12.2 0.5 11 5.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 RUS91067.1 - 0.078 13.2 0.5 3.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_PrkA PF08298.11 RUS91067.1 - 0.088 11.7 0.4 7.2 5.4 0.2 2.2 2 0 0 2 2 2 0 PrkA AAA domain TrwB_AAD_bind PF10412.9 RUS91067.1 - 0.21 10.5 0.9 2.7 6.8 0.1 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.15 RUS91067.1 - 0.41 9.4 1.3 11 4.7 0.1 2.6 3 0 0 3 3 3 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 RUS91067.1 - 0.87 9.3 2.2 24 4.6 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sulfotransfer_2 PF03567.14 RUS91068.1 - 1.6e-22 80.6 8.1 5.4e-22 78.9 0.7 3.1 3 1 0 3 3 3 2 Sulfotransferase family Apt1 PF10351.9 RUS91068.1 - 1.2 7.9 33.1 0.06 12.2 10.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Aminotran_1_2 PF00155.21 RUS91069.1 - 1.9e-42 145.7 0.0 2.6e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Fer4_23 PF18009.1 RUS91069.1 - 0.042 14.3 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain DUF1846 PF08903.11 RUS91069.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Alpha_L_fucos PF01120.17 RUS91070.1 - 4.6e-110 368.4 5.1 5.6e-110 368.1 5.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 RUS91070.1 - 3.3e-24 85.3 0.1 6.4e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Phage_Treg PF04761.12 RUS91070.1 - 0.039 14.0 0.2 0.19 11.8 0.2 2.1 1 1 1 2 2 2 0 Lactococcus bacteriophage putative transcription regulator LRR_8 PF13855.6 RUS91071.1 - 4.3e-13 48.8 11.5 1.8e-08 34.0 0.2 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RUS91071.1 - 6.3e-12 45.5 12.6 7.6e-05 23.0 0.0 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS91071.1 - 0.0012 19.0 10.5 2.1 9.2 0.0 5.8 5 3 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 RUS91071.1 - 0.0086 16.1 8.8 0.5 10.6 0.4 5.0 5 0 0 5 5 5 1 Leucine Rich repeat NAD_binding_10 PF13460.6 RUS91072.1 - 6.1e-41 140.3 0.0 7.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RUS91072.1 - 8.2e-09 35.4 0.0 1.3e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 RUS91072.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 RUS91072.1 - 0.0049 17.1 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 RUS91072.1 - 0.0081 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 RUS91072.1 - 0.0096 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 RUS91072.1 - 0.014 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 RUS91072.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Sulfotransfer_2 PF03567.14 RUS91073.1 - 4.1e-06 26.9 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS91074.1 - 1.5e-21 77.5 0.1 1.8e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family TMEM164 PF14808.6 RUS91075.1 - 7.1e-81 271.3 11.1 9.9e-81 270.8 11.1 1.1 1 0 0 1 1 1 1 TMEM164 family Sugar_tr PF00083.24 RUS91076.1 - 9.9e-33 113.7 21.7 1.3e-32 113.3 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS91076.1 - 9.3e-22 77.4 32.2 2.8e-18 66.0 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2417 PF10329.9 RUS91076.1 - 1.9 7.8 14.9 0.027 13.9 6.5 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) SH3_1 PF00018.28 RUS91077.1 - 1.5e-39 133.3 0.7 2e-14 52.9 0.1 3.7 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 RUS91077.1 - 1.2e-37 127.5 0.5 4.6e-16 58.4 0.0 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 RUS91077.1 - 2.6e-27 94.2 0.1 3.5e-13 49.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 RUS91077.1 - 6.2e-20 71.1 0.0 1.4e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 RUS91077.1 - 5.6e-12 45.8 1.9 0.0057 16.9 0.3 3.4 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_10 PF17902.1 RUS91077.1 - 6.2e-07 29.4 0.1 0.0024 17.9 0.0 3.4 3 0 0 3 3 3 1 SH3 domain SH3_16 PF18348.1 RUS91077.1 - 1.5e-05 24.7 0.0 0.072 12.9 0.0 2.7 3 0 0 3 3 3 2 Bacterial dipeptidyl-peptidase Sh3 domain hSH3 PF14603.6 RUS91077.1 - 0.00078 19.8 0.0 13 6.3 0.0 3.4 3 0 0 3 3 3 1 Helically-extended SH3 domain SH2_2 PF14633.6 RUS91077.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 SH2 domain Pex26 PF07163.12 RUS91078.1 - 0.17 11.2 4.6 0.14 11.5 3.3 1.5 2 0 0 2 2 2 0 Pex26 protein Pex14_N PF04695.13 RUS91078.1 - 0.5 11.0 21.1 0.84 10.3 21.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SMN PF06003.12 RUS91078.1 - 3.5 6.8 6.3 5.1 6.3 6.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TFIIA PF03153.13 RUS91078.1 - 4 7.3 23.9 5.5 6.9 23.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 RUS91078.1 - 5.3 5.2 17.3 6.6 4.9 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 RUS91078.1 - 6 6.2 9.7 9.3 5.6 9.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Folate_rec PF03024.14 RUS91079.1 - 8.9e-22 77.8 3.8 1.1e-21 77.5 3.8 1.0 1 0 0 1 1 1 1 Folate receptor family Otopetrin PF03189.13 RUS91079.1 - 0.057 12.2 0.1 0.057 12.2 0.1 1.1 1 0 0 1 1 1 0 Otopetrin SPOC PF07744.13 RUS91080.1 - 4.9e-36 123.9 0.0 2.3e-35 121.7 0.0 1.9 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 RUS91080.1 - 8.1e-29 99.3 0.0 5e-13 48.7 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RUS91080.1 - 9.9e-07 28.8 0.1 0.041 14.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RUS91080.1 - 9.2e-05 22.4 0.0 0.077 13.0 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 RUS91080.1 - 0.0098 15.9 0.0 0.72 9.9 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RED_N PF07808.13 RUS91080.1 - 5.6 6.5 5.6 10 5.6 5.6 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Pkinase PF00069.25 RUS91081.1 - 1.5e-67 227.7 0.0 2.5e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91081.1 - 3.9e-31 108.3 0.0 5.7e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS91081.1 - 6.9e-06 25.6 0.8 1.1e-05 24.9 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS91081.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 RUS91082.1 - 1.8e-55 188.2 0.4 3.5e-55 187.2 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91082.1 - 1.4e-43 149.1 0.4 2e-43 148.5 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS91082.1 - 3.2e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS91082.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 RUS91082.1 - 0.01 15.4 0.2 0.17 11.4 0.1 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Meleagrin PF08189.11 RUS91082.1 - 0.013 15.1 0.9 0.035 13.8 0.9 1.7 1 0 0 1 1 1 0 Meleagrin/Cygnin family APH PF01636.23 RUS91082.1 - 0.014 15.3 0.0 3.8 7.4 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 RUS91082.1 - 0.062 12.9 0.3 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 RIO1 family DDE_Tnp_4 PF13359.6 RUS91083.1 - 1.9e-40 138.1 0.0 2.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 RUS91083.1 - 2.9e-13 49.9 0.0 1.6e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 RUS91083.1 - 2.3e-10 40.5 0.1 7e-09 35.6 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 RUS91083.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 RUS91083.1 - 0.004 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 RUS91083.1 - 0.12 12.3 0.5 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 RUS91083.1 - 0.15 11.9 0.1 0.5 10.3 0.1 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain 7tm_1 PF00001.21 RUS91084.1 - 1.1e-48 165.9 4.2 1.5e-48 165.4 4.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91084.1 - 0.00034 20.1 11.3 0.00057 19.3 11.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS91084.1 - 0.035 13.9 9.2 0.058 13.1 9.2 1.3 1 0 0 1 1 1 0 Olfactory receptor 7tm_1 PF00001.21 RUS91085.1 - 2.3e-18 66.5 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TFIIF_beta PF02270.15 RUS91086.1 - 2.9e-22 78.5 0.1 5.1e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 RUS91086.1 - 1.3e-13 51.7 3.2 1.9e-12 48.0 0.2 3.0 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus GN3L_Grn1 PF08701.11 RUS91086.1 - 1 9.5 9.3 1.7 8.8 6.5 2.4 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Pkinase PF00069.25 RUS91087.1 - 7.1e-71 238.7 0.0 1.2e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91087.1 - 1.1e-51 175.7 0.0 1.7e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RUS91087.1 - 1.2e-05 24.4 1.1 1.6e-05 23.9 0.0 1.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 RUS91087.1 - 0.0016 17.8 0.0 0.059 12.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 RUS91087.1 - 0.0027 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 RUS91087.1 - 0.07 12.1 0.1 0.39 9.6 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain SUIM_assoc PF16619.5 RUS91087.1 - 0.28 11.3 7.9 0.8 9.8 7.9 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GFO_IDH_MocA PF01408.22 RUS91090.1 - 3.5e-22 79.5 0.0 4.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 RUS91090.1 - 0.00044 20.8 0.0 0.00075 20.0 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 RUS91090.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TetR_C_27 PF17935.1 RUS91091.1 - 5.9e-05 23.1 10.5 0.51 10.4 1.6 4.1 1 1 3 4 4 4 2 Tetracyclin repressor-like, C-terminal domain Vac_Fusion PF02346.16 RUS91091.1 - 0.026 14.2 4.9 4.8 6.9 0.1 3.7 1 1 2 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FAD_SOX PF18371.1 RUS91091.1 - 0.027 14.8 5.7 6.5 7.2 0.3 4.1 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Chordopox_E11 PF06138.12 RUS91091.1 - 0.04 14.2 15.7 2.8 8.3 0.6 4.9 1 1 4 5 5 5 0 Chordopoxvirus E11 protein Consortin_C PF15281.6 RUS91091.1 - 0.15 12.0 2.3 5.5 7.0 0.1 2.5 1 1 0 2 2 2 0 Consortin C-terminus LXG PF04740.12 RUS91091.1 - 0.19 11.4 2.2 7.4 6.2 0.1 2.8 1 1 1 3 3 3 0 LXG domain of WXG superfamily DASH_Duo1 PF08651.10 RUS91091.1 - 0.19 11.5 5.6 6.4 6.6 0.6 2.9 1 1 2 3 3 3 0 DASH complex subunit Duo1 DUF5063 PF16702.5 RUS91091.1 - 0.2 12.0 1.9 1.4 9.3 0.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5063) Mei5_like PF17021.5 RUS91091.1 - 0.71 9.9 13.2 18 5.4 2.1 3.9 1 1 2 3 3 3 0 Putative double-strand recombination repair-like BLOC1_2 PF10046.9 RUS91091.1 - 1.2 9.5 9.9 18 5.7 0.5 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MREG PF15812.5 RUS91091.1 - 4.5 7.6 9.1 36 4.6 1.0 3.5 1 1 1 2 2 2 0 Melanoregulin ShK PF01549.24 RUS91092.1 - 6.7e-22 77.7 41.4 2.9e-09 37.3 10.8 3.8 3 0 0 3 3 3 3 ShK domain-like CAP PF00188.26 RUS91092.1 - 8.6e-18 65.4 1.6 2.2e-17 64.1 1.6 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-CCCH PF00642.24 RUS91092.1 - 7.8e-05 22.5 2.1 0.77 9.7 0.1 4.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4780 PF16012.5 RUS91092.1 - 2.1 7.8 4.4 4.8 6.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) Ins145_P3_rec PF08709.11 RUS91093.1 - 1.8e-28 99.2 5.3 3.8e-26 91.6 1.8 2.8 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 RUS91093.1 - 2.7e-24 85.7 9.9 7e-16 58.3 3.3 4.9 3 1 0 3 3 3 2 RIH domain MIR PF02815.19 RUS91093.1 - 6.2e-16 58.8 0.1 4.5e-10 39.7 0.0 3.8 2 1 0 2 2 2 2 MIR domain RIH_assoc PF08454.11 RUS91093.1 - 2.6e-09 36.8 6.9 1.5e-07 31.2 0.2 4.6 5 0 0 5 5 5 2 RyR and IP3R Homology associated Fascin PF06268.13 RUS91093.1 - 0.089 13.0 0.1 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Fascin domain Tup_N PF08581.10 RUS91097.1 - 0.0067 16.7 1.9 0.0067 16.7 1.9 5.8 6 1 1 7 7 7 1 Tup N-terminal EF-G-binding_N PF07299.11 RUS91097.1 - 0.6 10.7 7.6 0.92 10.1 0.2 3.2 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal CENP-B_dimeris PF09026.10 RUS91097.1 - 2.7 8.4 21.6 2.8 8.4 7.1 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 RUS91098.1 - 1.2e-20 73.8 29.1 1.1e-11 44.2 2.6 3.5 2 2 0 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 RUS91098.1 - 3.8e-05 22.2 0.5 0.024 12.9 0.0 3.0 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family CbtA PF09490.10 RUS91098.1 - 0.0057 16.4 1.2 0.0057 16.4 1.2 2.1 2 0 0 2 2 2 1 Probable cobalt transporter subunit (CbtA) CPBP PF02517.16 RUS91098.1 - 0.039 14.3 1.6 0.35 11.3 0.1 3.2 1 1 0 2 2 2 0 CPBP intramembrane metalloprotease DUF4231 PF14015.6 RUS91098.1 - 0.17 12.4 0.1 0.7 10.4 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF5391 PF17369.2 RUS91098.1 - 1.2 9.1 6.8 0.26 11.3 2.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5391) Oxidored_q2 PF00420.24 RUS91098.1 - 7.8 6.2 8.6 9.4 5.9 2.9 2.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CENP-I PF07778.11 RUS91099.1 - 1.3e-77 261.7 8.1 1.9e-77 261.1 8.1 1.2 1 0 0 1 1 1 1 Mis6 Dzip-like_N PF13815.6 RUS91101.1 - 4.3e-40 136.4 5.0 4.3e-40 136.4 5.0 4.6 5 0 0 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF244 PF03112.14 RUS91101.1 - 0.007 16.2 5.6 0.33 10.8 0.5 2.5 2 0 0 2 2 2 2 Uncharacterized protein family (ORF7) DUF zf-Di19 PF05605.12 RUS91101.1 - 0.0083 16.4 0.1 0.027 14.7 0.1 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 RUS91101.1 - 0.01 16.6 2.0 0.024 15.4 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91101.1 - 0.025 15.0 0.9 0.025 15.0 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_1 PF00515.28 RUS91102.1 - 3.7e-28 96.2 11.8 2.1e-06 27.3 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS91102.1 - 6.1e-26 88.4 16.5 0.00013 21.8 0.0 8.7 10 0 0 10 10 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 RUS91102.1 - 1.8e-23 82.8 13.4 6.5e-08 33.0 1.8 6.0 3 3 3 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 RUS91102.1 - 3e-22 78.5 1.8 3e-22 78.5 1.8 3.2 4 0 0 4 4 3 1 DnaJ domain TPR_14 PF13428.6 RUS91102.1 - 2.9e-21 74.3 8.0 0.018 15.8 0.0 8.2 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 RUS91102.1 - 3.8e-19 69.0 0.3 4.9e-07 30.3 0.0 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91102.1 - 8.4e-17 59.9 12.3 0.012 15.7 0.1 7.0 8 0 0 8 8 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RUS91102.1 - 1.1e-12 47.4 17.3 0.00051 19.7 0.5 6.6 7 1 2 9 9 7 4 TPR repeat TPR_17 PF13431.6 RUS91102.1 - 1.8e-12 46.7 11.2 0.0078 16.5 0.0 8.0 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 RUS91102.1 - 1.9e-11 44.0 6.3 0.0031 17.6 0.1 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 RUS91102.1 - 2.9e-10 40.1 8.3 0.31 11.8 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS91102.1 - 8.7e-10 38.7 12.2 0.0056 16.9 0.1 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RUS91102.1 - 1.7e-09 37.8 9.3 0.056 13.7 0.1 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 RUS91102.1 - 9.2e-09 35.5 18.3 0.098 13.0 2.8 6.5 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.6 RUS91102.1 - 6.7e-08 32.1 7.4 0.021 14.1 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS91102.1 - 1.6e-07 31.2 12.6 0.1 12.7 0.3 5.7 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 RUS91102.1 - 3.2e-07 29.7 18.9 0.00013 21.0 1.8 3.7 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 RUS91102.1 - 1.1e-05 25.1 2.5 0.02 14.6 0.0 3.2 2 1 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 RUS91102.1 - 6.4e-05 22.7 0.2 6.4e-05 22.7 0.2 3.2 2 2 0 2 2 2 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 RUS91102.1 - 0.00019 21.9 7.2 1.4 9.3 0.2 4.7 3 2 1 4 4 4 2 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 RUS91102.1 - 0.00075 20.0 9.9 1.9 8.9 2.9 4.6 2 2 1 4 4 4 1 Alkyl sulfatase dimerisation ANAPC5 PF12862.7 RUS91102.1 - 0.002 18.1 1.1 0.08 13.0 0.0 3.8 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 MCR_alpha_N PF02745.15 RUS91102.1 - 0.024 14.0 1.0 0.039 13.3 1.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain PRAI PF00697.22 RUS91102.1 - 0.078 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ArnB_C PF18677.1 RUS91102.1 - 0.086 12.9 5.6 0.13 12.4 3.7 2.3 2 0 0 2 2 1 0 Archaellum regulatory network B, C-terminal domain TPR_4 PF07721.14 RUS91102.1 - 0.21 12.3 8.8 8.6 7.3 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4363 PF14276.6 RUS91102.1 - 0.95 9.6 13.6 1 9.5 1.6 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4363) TPR_10 PF13374.6 RUS91102.1 - 3.4 7.7 11.7 3.8 7.5 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat SesA PF17107.5 RUS91102.1 - 4 7.7 9.8 4.6 7.5 4.6 3.0 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4065 PF13274.6 RUS91103.1 - 0.34 11.8 2.5 0.73 10.7 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) DUF4484 PF14831.6 RUS91103.1 - 1.2 9.2 7.6 1 9.4 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Cullin_binding PF03556.15 RUS91104.1 - 6.4e-38 129.9 1.9 6.4e-38 129.9 1.9 2.0 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 RUS91104.1 - 2.3e-09 36.9 0.0 6.7e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain Aa_trans PF01490.18 RUS91105.1 - 1.1e-14 53.9 3.8 1.2e-14 53.8 3.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RUS91105.1 - 0.0073 15.4 1.9 0.0086 15.2 1.9 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Spore_permease PF03845.13 RUS91105.1 - 0.042 12.7 2.5 0.049 12.4 2.5 1.1 1 0 0 1 1 1 0 Spore germination protein Aa_trans PF01490.18 RUS91106.1 - 3e-71 240.3 21.5 3.6e-71 240.0 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein p450 PF00067.22 RUS91108.1 - 5e-58 197.0 0.0 6.9e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ChpXY PF10216.9 RUS91108.1 - 0.058 12.5 0.4 0.085 12.0 0.4 1.2 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) PRP21_like_P PF12230.8 RUS91109.1 - 7.8e-19 68.4 12.9 7.8e-19 68.4 12.9 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 RUS91109.1 - 5.8e-13 48.4 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RUS91109.1 - 0.15 12.5 0.0 0.57 10.7 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain CDC45 PF02724.14 RUS91109.1 - 0.78 8.0 7.0 1.2 7.4 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein EMP70 PF02990.16 RUS91110.1 - 2.3e-220 732.7 6.7 3.3e-220 732.2 6.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3134 PF11332.8 RUS91111.1 - 0.13 12.6 1.1 0.16 12.3 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3134) Tctex-1 PF03645.13 RUS91112.1 - 1e-26 93.1 0.2 1.4e-26 92.7 0.2 1.2 1 0 0 1 1 1 1 Tctex-1 family Kinesin PF00225.23 RUS91113.1 - 3.7e-05 22.8 0.0 3.7e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Spt20 PF12090.8 RUS91113.1 - 2.7 7.5 10.3 5.6 6.5 10.3 1.5 1 0 0 1 1 1 0 Spt20 family SelP_N PF04592.14 RUS91113.1 - 9.8 5.5 19.7 24 4.2 19.7 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Keratin_B2 PF01500.17 RUS91114.1 - 6.7e-08 32.7 23.6 0.36 10.8 6.9 4.1 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein Pentapeptide_4 PF13599.6 RUS91114.1 - 8.2e-07 29.1 0.0 0.17 12.1 0.0 3.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) CfAFP PF05264.11 RUS91114.1 - 0.015 15.3 35.2 2.7 8.0 8.6 3.6 1 1 3 4 4 4 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1126 PF06565.12 RUS91114.1 - 0.051 13.4 0.1 59 3.6 0.0 4.1 1 1 2 3 3 3 0 DUF1126 PH-like domain PMG PF05287.12 RUS91114.1 - 0.81 9.7 31.8 12 5.9 6.8 3.2 1 1 1 2 2 2 0 PMG protein DUF4954 PF16314.5 RUS91114.1 - 4.3 5.3 6.6 5.9 4.9 0.3 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4954) Keratin_B2_2 PF13885.6 RUS91114.1 - 6.5 6.8 9.8 29 4.7 0.3 5.0 1 1 3 4 4 4 0 Keratin, high sulfur B2 protein DUF3678 PF12435.8 RUS91115.1 - 1.1e-07 31.1 29.9 7.5 6.0 0.1 8.4 8 0 0 8 8 8 8 Protein of unknown function (DUF3678) RecA_dep_nuc PF16786.5 RUS91115.1 - 0.0013 18.9 17.3 77 3.5 0.1 7.0 7 0 0 7 7 7 7 Recombination enhancement, RecA-dependent nuclease Kinesin PF00225.23 RUS91117.1 - 1.9e-26 92.8 0.0 2.3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RUS91117.1 - 3.3e-13 49.8 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding NADHdeh_related PF10125.9 RUS91118.1 - 1.2e-08 34.6 25.1 0.45 9.8 0.1 8.5 1 1 8 9 9 9 9 NADH dehydrogenase I, subunit N related protein DUF1279 PF06916.13 RUS91118.1 - 9.7 6.8 16.1 28 5.3 0.8 5.5 1 1 7 8 8 8 0 Protein of unknown function (DUF1279) GNAT_like PF18407.1 RUS91119.1 - 0.0038 17.5 1.4 0.46 10.9 0.1 4.2 2 1 2 4 4 4 1 GCN5-related N-acetyltransferase like domain DUF2345 PF10106.9 RUS91120.1 - 9.2e-08 32.1 42.3 0.073 12.9 6.4 5.5 1 1 4 5 5 5 5 Uncharacterized protein conserved in bacteria (DUF2345) ChlamPMP_M PF07548.11 RUS91120.1 - 3.1 7.7 46.3 3.5 7.6 3.1 6.5 1 1 4 5 5 5 0 Chlamydia polymorphic membrane protein middle domain DUF2012 PF09430.10 RUS91122.1 - 0.077 13.1 0.1 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) PHD PF00628.29 RUS91122.1 - 0.66 9.9 15.0 1.3 8.9 15.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-CCHC PF00098.23 RUS91123.1 - 1.5e-05 24.8 3.6 2.6e-05 24.1 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RUS91123.1 - 0.001 18.9 3.2 0.0015 18.3 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RUS91123.1 - 0.0068 16.4 1.4 0.018 15.0 1.2 1.9 1 1 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RUS91123.1 - 0.075 12.8 3.5 0.14 11.8 3.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SAP PF02037.27 RUS91124.1 - 0.00029 20.5 0.1 0.0012 18.6 0.1 2.0 1 1 0 1 1 1 1 SAP domain Tnp_zf-ribbon_2 PF13842.6 RUS91125.1 - 0.0011 19.7 13.5 0.0029 18.4 13.5 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon CCDC144C PF14915.6 RUS91125.1 - 0.0045 16.2 1.0 0.0071 15.5 1.0 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Rootletin PF15035.6 RUS91125.1 - 0.029 14.4 1.2 0.056 13.5 1.2 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SMN PF06003.12 RUS91125.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) MADF_DNA_bdg PF10545.9 RUS91127.1 - 2.3e-15 56.7 1.2 3.3e-15 56.2 1.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Jnk-SapK_ap_N PF09744.9 RUS91127.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Robl_LC7 PF03259.17 RUS91128.1 - 2.6e-24 84.8 0.0 3.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 RUS91128.1 - 0.00069 19.5 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 RUS91128.1 - 0.0027 18.0 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain AAA PF00004.29 RUS91129.1 - 3.3e-50 169.9 0.0 6e-39 133.5 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RUS91129.1 - 9.2e-11 41.4 0.2 2.3e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RUS91129.1 - 3.2e-09 37.2 0.6 0.0027 18.0 0.1 4.3 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 RUS91129.1 - 3.2e-06 27.2 0.1 0.0004 20.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RUS91129.1 - 3.3e-06 27.3 0.0 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 RUS91129.1 - 4e-06 27.4 0.0 0.026 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 RUS91129.1 - 5e-06 26.6 0.0 7.6e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 RUS91129.1 - 5e-06 27.0 0.1 0.02 15.3 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 RUS91129.1 - 7.2e-06 25.4 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 RUS91129.1 - 1.6e-05 24.9 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RUS91129.1 - 1.8e-05 24.9 0.0 0.027 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RUS91129.1 - 2.1e-05 24.3 0.1 0.029 14.1 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RUS91129.1 - 3.6e-05 24.1 0.0 0.085 13.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.17 RUS91129.1 - 4.6e-05 23.1 0.2 0.00064 19.5 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 RUS91129.1 - 8.5e-05 22.0 0.6 0.0055 16.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 RUS91129.1 - 0.00086 19.7 0.2 0.28 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 RUS91129.1 - 0.0012 18.3 1.8 0.0042 16.5 0.1 2.6 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 RUS91129.1 - 0.0017 18.0 1.3 2.1 7.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 RUS91129.1 - 0.0017 18.6 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 RUS91129.1 - 0.0017 18.3 0.1 2.8 7.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 RUS91129.1 - 0.0018 18.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 RUS91129.1 - 0.0019 17.8 0.1 0.031 13.8 0.0 2.5 2 1 1 3 3 3 1 P-loop containing dynein motor region AAA_3 PF07726.11 RUS91129.1 - 0.0023 17.8 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RUS91129.1 - 0.0026 17.5 0.0 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS91129.1 - 0.0042 16.9 0.3 0.11 12.2 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 RUS91129.1 - 0.0049 16.6 2.5 0.16 11.7 0.1 3.2 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RUS91129.1 - 0.0056 15.9 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 RUS91129.1 - 0.0076 16.8 0.1 0.26 11.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 RUS91129.1 - 0.0098 15.2 0.0 2.2 7.4 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 RUS91129.1 - 0.063 12.7 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 RUS91129.1 - 0.071 13.4 1.3 0.75 10.1 0.4 2.8 2 1 0 2 2 2 0 AAA domain DUF1533 PF07550.11 RUS91129.1 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Sigma54_activat PF00158.26 RUS91129.1 - 0.075 12.7 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 RUS91129.1 - 0.083 12.2 2.8 1.3 8.3 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin Parvo_NS1 PF01057.17 RUS91129.1 - 0.098 11.7 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.10 RUS91129.1 - 0.13 11.6 0.5 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 RUS91129.1 - 0.46 10.2 3.8 1.1 9.0 1.4 2.5 2 1 0 2 2 2 0 AAA domain DAO PF01266.24 RUS91130.1 - 1.1e-50 173.3 0.0 1.5e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 RUS91130.1 - 1.8e-34 118.3 0.2 4.3e-34 117.1 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 RUS91130.1 - 9.6e-11 42.0 0.5 2.3e-10 40.7 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS91130.1 - 3.3e-07 29.4 0.1 0.036 13.6 0.0 2.8 2 0 0 2 2 2 2 EF hand FAD_binding_2 PF00890.24 RUS91130.1 - 9.4e-07 28.2 0.1 0.0012 18.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain EF-hand_6 PF13405.6 RUS91130.1 - 6.2e-06 25.7 0.3 0.012 15.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain FAD_oxidored PF12831.7 RUS91130.1 - 2.3e-05 24.0 0.2 0.00066 19.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 RUS91130.1 - 0.00011 21.4 0.4 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 RUS91130.1 - 0.00074 18.9 0.1 0.36 10.0 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain EF-hand_8 PF13833.6 RUS91130.1 - 0.0011 18.8 0.1 0.0068 16.2 0.1 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 RUS91130.1 - 0.0039 17.5 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Pyr_redox_2 PF07992.14 RUS91130.1 - 0.0099 15.1 0.4 0.11 11.7 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 RUS91130.1 - 0.018 15.0 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Lycopene_cycl PF05834.12 RUS91130.1 - 0.031 13.3 0.6 7.7 5.5 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 RUS91130.1 - 0.052 12.8 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb4 PF03874.16 RUS91130.1 - 0.96 9.8 6.1 8.6 6.7 2.9 3.3 3 1 0 3 3 2 0 RNA polymerase Rpb4 7tm_3 PF00003.22 RUS91132.1 - 1.1e-48 166.0 19.8 1.5e-48 165.6 19.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EGF_CA PF07645.15 RUS91132.1 - 0.0059 16.8 0.6 0.019 15.2 0.6 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain hEGF PF12661.7 RUS91132.1 - 0.023 15.3 0.4 0.077 13.7 0.4 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF cEGF PF12662.7 RUS91132.1 - 0.024 14.5 0.7 0.067 13.1 0.7 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like CAP59_mtransfer PF11735.8 RUS91132.1 - 0.72 9.5 3.2 1.5 8.4 3.2 1.5 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 PRIMA1 PF16101.5 RUS91132.1 - 1.6 8.8 5.2 0.56 10.3 0.2 2.9 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 PLAC8 PF04749.17 RUS91134.1 - 1.6e-22 80.3 4.8 1.8e-22 80.1 4.8 1.0 1 0 0 1 1 1 1 PLAC8 family DEAD PF00270.29 RUS91135.1 - 2.9e-35 121.6 0.0 4.8e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RUS91135.1 - 1.7e-23 83.0 0.1 4.7e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS91135.1 - 6.7e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 RUS91135.1 - 0.058 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SWI2_SNF2 PF18766.1 RUS91135.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase C2 PF00168.30 RUS91136.1 - 4.2e-19 68.8 0.0 9.8e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 RUS91136.1 - 0.081 13.6 1.0 0.5 11.0 0.0 2.8 3 0 0 3 3 3 0 Putative heavy-metal-binding Ank_2 PF12796.7 RUS91137.1 - 8e-17 61.6 0.0 8e-12 45.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91137.1 - 1.1e-15 57.7 0.3 2.5e-07 31.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91137.1 - 7.2e-15 53.6 0.3 0.0007 19.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RUS91137.1 - 2.2e-14 53.1 6.6 7.7e-06 26.1 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RUS91137.1 - 3.9e-14 52.5 0.1 0.0035 17.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) IRF PF00605.17 RUS91137.1 - 0.015 15.6 0.5 0.028 14.7 0.5 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Ldl_recept_a PF00057.18 RUS91138.1 - 9.7e-17 60.9 33.3 1.3e-08 34.9 12.8 3.3 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 RUS91138.1 - 2.9e-08 34.2 0.1 1.1e-07 32.3 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS91138.1 - 1.8e-05 25.0 0.0 5.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS91138.1 - 2e-05 24.6 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS91138.1 - 2.9e-05 24.1 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 RUS91138.1 - 0.00029 21.0 0.1 0.1 12.8 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Alpha-amylase_C PF02806.18 RUS91141.1 - 7.3e-24 84.1 0.0 1.6e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 RUS91141.1 - 3.2e-15 56.5 0.2 1.7e-11 44.3 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 RUS91141.1 - 2e-09 37.7 0.0 5.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.18 RUS91141.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) LSM PF01423.22 RUS91144.1 - 3.5e-13 49.0 0.3 4.3e-13 48.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain AKAP_110 PF05716.13 RUS91144.1 - 0.13 10.5 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Nop PF01798.18 RUS91145.1 - 1.6e-84 283.0 0.0 3.4e-84 281.9 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RUS91145.1 - 1.1e-18 67.4 3.0 4.9e-18 65.3 3.0 2.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 RUS91145.1 - 0.55 10.3 35.8 1 9.4 35.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 RUS91145.1 - 5.7 6.7 21.8 8.8 6.1 21.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_7N PF13733.6 RUS91146.1 - 2.8e-50 169.4 0.0 4.5e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS91146.1 - 5.9e-28 96.3 0.4 1.1e-27 95.5 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 RUS91146.1 - 0.00044 19.8 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RCC1 PF00415.18 RUS91147.1 - 8.2e-27 93.6 3.7 3.9e-12 46.6 0.1 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS91147.1 - 1e-08 34.8 14.4 2.8e-05 23.8 0.1 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat zf-RRN7 PF11781.8 RUS91147.1 - 0.013 15.2 0.4 0.038 13.7 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RCC1 PF00415.18 RUS91148.1 - 1.3e-10 41.7 0.1 6.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RUS91148.1 - 1e-07 31.5 0.2 0.00048 19.9 0.2 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat PH PF00169.29 RUS91148.1 - 0.0032 18.0 0.0 0.0073 16.8 0.0 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 RUS91148.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain VPS9 PF02204.18 RUS91149.1 - 6.3e-19 68.1 0.2 1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 RUS91149.1 - 2.4e-05 23.9 16.5 0.039 13.8 3.6 4.1 4 0 0 4 4 4 3 MORN repeat ASH PF15780.5 RUS91152.1 - 7.2e-28 96.7 14.6 8.1e-05 22.8 0.1 10.6 11 0 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RUS91152.1 - 1.8e-08 34.2 11.5 13 5.7 0.0 9.5 10 0 0 10 10 10 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RUS91152.1 - 2.6e-07 30.8 5.8 0.36 11.1 0.0 5.8 6 0 0 6 6 6 3 Transmembrane protein 131-like PapD-like PF14874.6 RUS91152.1 - 3.9e-06 26.9 1.8 20 5.4 0.0 6.9 7 0 0 7 7 7 2 Flagellar-associated PapD-like Big_4 PF07532.11 RUS91152.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) PP2C PF00481.21 RUS91153.1 - 7.9e-52 176.4 0.0 1.1e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RUS91153.1 - 0.00065 19.4 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RUS91153.1 - 0.007 16.3 0.1 0.48 10.3 0.1 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) tRNA_edit PF04073.15 RUS91154.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain RNase_II_C_S1 PF18614.1 RUS91155.1 - 0.049 13.6 0.4 0.093 12.7 0.4 1.5 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain RXT2_N PF08595.11 RUS91155.1 - 4.9 7.2 6.8 8.2 6.4 6.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal KRAP_IP3R_bind PF14722.6 RUS91156.1 - 6.2e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain PKcGMP_CC PF16808.5 RUS91160.1 - 0.022 14.6 2.0 0.045 13.6 2.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CR6_interact PF10147.9 RUS91160.1 - 0.65 9.7 3.5 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF641 PF04859.12 RUS91160.1 - 0.7 10.2 3.6 0.24 11.7 0.4 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 RUS91160.1 - 8.3 5.8 14.6 0.12 11.8 3.2 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DNA_topoisoIV PF00521.20 RUS91161.1 - 6e-129 430.7 0.1 6e-129 430.7 0.1 2.1 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RUS91161.1 - 4.6e-49 166.0 4.7 4.6e-49 166.0 4.7 2.8 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RUS91161.1 - 4.5e-33 114.2 1.9 1.1e-32 112.9 1.9 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RUS91161.1 - 1.2e-14 54.8 0.0 3.7e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RUS91161.1 - 9.2e-09 35.5 0.0 3.3e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DTHCT PF08070.11 RUS91161.1 - 5.9e-07 30.2 22.3 5.9e-07 30.2 22.3 7.2 5 2 2 7 7 7 1 DTHCT (NUC029) region DUF4238 PF14022.6 RUS91161.1 - 0.014 14.9 0.0 0.094 12.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) PDZ PF00595.24 RUS91162.1 - 2.4e-10 40.6 0.0 6.6e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS91162.1 - 3.9e-10 39.4 0.0 1.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 RUS91162.1 - 1.6e-07 31.5 0.0 6.5e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 PDZ domain Vinculin PF01044.19 RUS91163.1 - 3.5e-69 234.1 12.4 7.1e-39 133.8 4.9 3.0 2 1 1 3 3 3 3 Vinculin family NodZ PF05830.11 RUS91163.1 - 0.045 12.6 0.1 0.092 11.5 0.1 1.5 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) I_LWEQ PF01608.17 RUS91163.1 - 0.77 10.0 8.4 2.8 8.2 0.3 4.0 3 1 0 3 3 3 0 I/LWEQ domain Pkinase PF00069.25 RUS91164.1 - 4.1e-67 226.3 0.0 4.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91164.1 - 4e-31 108.2 0.0 5.4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS91164.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RUS91164.1 - 0.0045 16.0 0.0 0.014 14.4 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS91164.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RUS91164.1 - 0.13 11.6 0.1 0.65 9.3 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS91164.1 - 0.16 11.6 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Ras PF00071.22 RUS91165.1 - 6.8e-22 77.8 0.2 8.7e-17 61.2 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 RUS91165.1 - 3.1e-15 56.4 0.0 4.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS91165.1 - 7.2e-06 26.1 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 RUS91165.1 - 0.00025 20.5 0.0 0.00058 19.4 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RUS91165.1 - 0.0005 19.7 0.4 0.01 15.4 0.1 2.5 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS91165.1 - 0.0093 15.9 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 RUS91165.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RUS91165.1 - 0.028 13.6 0.0 3.1 6.8 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit CoA_binding_3 PF13727.6 RUS91165.1 - 0.046 13.7 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain DUF3974 PF13120.6 RUS91165.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) PduV-EutP PF10662.9 RUS91165.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 RUS91166.1 - 3.9e-05 24.3 2.7 0.86 10.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91166.1 - 0.00099 19.4 0.0 20 5.6 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RIC3 PF15361.6 RUS91167.1 - 0.039 14.4 0.0 0.059 13.8 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Somatomedin_B PF01033.17 RUS91168.1 - 7.4e-07 29.5 13.7 2.2e-06 28.0 13.7 1.9 1 0 0 1 1 1 1 Somatomedin B domain NIF PF03031.18 RUS91169.1 - 2.3e-48 163.9 0.3 2.9e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 RUS91169.1 - 0.074 12.5 0.2 0.15 11.5 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF705) Frizzled PF01534.17 RUS91170.1 - 6.8e-139 462.4 18.1 2.1e-138 460.8 18.9 1.4 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RUS91170.1 - 3e-32 111.5 4.4 5.2e-32 110.8 4.4 1.4 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 RUS91171.1 - 9.1e-138 458.7 17.1 1.4e-137 458.1 17.1 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RUS91171.1 - 2.1e-30 105.6 3.6 3.7e-30 104.8 3.6 1.4 1 0 0 1 1 1 1 Fz domain LRR_8 PF13855.6 RUS91172.1 - 1.6e-33 114.3 44.2 1.1e-12 47.5 1.9 9.5 5 3 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 RUS91172.1 - 3.9e-18 65.2 48.1 7.3e-05 23.1 1.0 12.1 9 2 4 13 13 13 6 Leucine Rich repeats (2 copies) TIR PF01582.20 RUS91172.1 - 5.2e-07 29.6 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS91172.1 - 1.1e-05 26.0 0.0 3.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 RUS91172.1 - 0.00027 20.9 0.2 0.031 14.3 0.0 3.5 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 RUS91172.1 - 0.0003 20.3 14.9 0.00059 19.4 0.8 4.5 2 1 2 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.6 RUS91172.1 - 0.017 15.2 34.2 1.3 9.3 0.2 10.0 12 0 0 12 12 12 0 Leucine Rich repeat LRR_1 PF00560.33 RUS91172.1 - 3.7 8.5 39.2 7.5 7.5 0.3 12.0 13 2 0 13 13 13 0 Leucine Rich Repeat 7tm_1 PF00001.21 RUS91173.1 - 2.1e-05 24.0 9.6 2.5e-05 23.7 9.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS91173.1 - 0.00018 21.2 11.0 0.00021 21.0 11.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3525 PF12039.8 RUS91173.1 - 0.15 10.7 0.3 0.26 10.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Gaa1 PF04114.14 RUS91173.1 - 0.3 10.1 7.7 0.35 9.8 7.7 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Retrotran_gag_3 PF14244.6 RUS91174.1 - 1.5e-05 24.7 8.0 2.6e+02 1.5 0.0 9.6 11 0 0 11 11 11 0 gag-polypeptide of LTR copia-type Colicin_K PF17500.2 RUS91175.1 - 0.011 16.3 0.1 7.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Colicin-K Phage_TTP_11 PF16460.5 RUS91175.1 - 0.037 13.9 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube, TTP, lambda-like YhfH PF14149.6 RUS91175.1 - 0.055 13.5 9.4 0.54 10.3 2.9 2.4 2 0 0 2 2 2 0 YhfH-like protein MCR PF18509.1 RUS91175.1 - 4.3 7.0 6.1 17 5.1 0.5 2.4 2 0 0 2 2 2 0 Magnetochrome domain TMEM151 PF14857.6 RUS91177.1 - 2.8 6.8 5.9 5.5 5.8 5.9 1.4 1 0 0 1 1 1 0 TMEM151 family Pox_A_type_inc PF04508.12 RUS91178.1 - 0.0096 15.7 1.1 1.8 8.6 0.1 3.7 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 RUS91178.1 - 0.013 15.6 4.1 0.013 15.6 4.1 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 RUS91178.1 - 0.022 14.8 21.6 3.9 7.7 0.5 4.1 3 1 1 4 4 4 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 RUS91178.1 - 0.022 14.8 20.6 0.063 13.4 1.8 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 RUS91178.1 - 0.04 14.0 19.3 0.4 10.8 0.1 4.3 4 0 0 4 4 4 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 RUS91178.1 - 0.042 13.9 19.6 0.1 12.6 2.9 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LOH1CR12 PF10158.9 RUS91178.1 - 0.13 12.3 8.6 1.1 9.3 1.7 2.3 1 1 1 2 2 2 0 Tumour suppressor protein FlaC_arch PF05377.11 RUS91178.1 - 0.27 11.7 0.2 0.27 11.7 0.2 4.0 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 RUS91178.1 - 0.64 9.6 15.2 0.8 9.2 15.2 1.2 1 0 0 1 1 1 0 TMCO5 family XkdW PF09636.10 RUS91178.1 - 0.78 9.9 5.8 0.5 10.5 2.7 2.0 1 1 1 2 2 2 0 XkdW protein Jnk-SapK_ap_N PF09744.9 RUS91178.1 - 1.3 9.2 19.2 0.46 10.7 2.2 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 RUS91178.1 - 2.1 8.4 8.8 4.8 7.2 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) SurA_N_2 PF13623.6 RUS91178.1 - 2.9 7.8 12.3 0.32 10.9 5.4 2.2 2 1 0 2 2 2 0 SurA N-terminal domain Plk4_PB2 PF18409.1 RUS91178.1 - 3.3 8.4 11.6 5.5 7.7 3.0 2.2 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF724 PF05266.14 RUS91178.1 - 3.6 7.4 14.2 0.26 11.1 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 RUS91178.1 - 4 7.4 11.1 1.1 9.2 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) YabA PF06156.13 RUS91178.1 - 4.1 8.1 15.5 5 7.8 6.6 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Phage_GP20 PF06810.11 RUS91178.1 - 5.9 6.7 14.5 2.6 7.9 0.7 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 BIR PF00653.21 RUS91179.1 - 1.1e-18 67.6 0.2 2.2e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UMPH-1 PF05822.12 RUS91180.1 - 6.4e-90 301.0 1.4 8.6e-90 300.6 1.4 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) FA_desaturase PF00487.24 RUS91181.1 - 5.6e-35 121.4 22.6 5.6e-35 121.4 22.6 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 RUS91181.1 - 1.5e-22 79.5 0.4 2.5e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MHCassoc_trimer PF08831.10 RUS91181.1 - 0.021 14.8 0.0 0.071 13.1 0.0 1.9 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF4133 PF13571.6 RUS91181.1 - 0.18 12.2 1.1 0.52 10.7 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) EIIC-GAT PF03611.14 RUS91181.1 - 0.19 10.8 2.6 0.36 9.9 2.6 1.4 1 0 0 1 1 1 0 PTS system sugar-specific permease component 7tm_1 PF00001.21 RUS91182.1 - 0.00012 21.5 16.2 0.00013 21.4 14.8 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS91182.1 - 0.82 9.2 18.6 0.087 12.4 14.1 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srt PF10321.9 RUS91182.1 - 1.7 7.5 15.1 0.24 10.3 11.2 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF418 PF04235.12 RUS91182.1 - 8.4 6.3 10.6 4.9 7.1 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF418) FA_desaturase PF00487.24 RUS91183.1 - 2.3e-37 129.2 18.5 3.3e-37 128.7 18.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 RUS91183.1 - 1.4e-22 79.6 0.3 2.5e-22 78.8 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 7tm_1 PF00001.21 RUS91185.1 - 1.4e-47 162.3 0.2 2.1e-47 161.7 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91185.1 - 2.5e-06 27.1 11.2 2.5e-06 27.1 11.2 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS91185.1 - 0.00015 21.7 7.8 0.00023 21.0 7.8 1.3 1 0 0 1 1 1 1 Olfactory receptor Git3 PF11710.8 RUS91185.1 - 0.023 14.4 15.3 0.039 13.7 15.3 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srx PF10328.9 RUS91185.1 - 0.46 10.1 19.0 0.032 13.9 13.7 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF373 PF04123.13 RUS91185.1 - 2.4 7.5 6.6 8.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TSP_3 PF02412.18 RUS91186.1 - 0.034 13.8 1.2 0.088 12.5 1.2 1.7 1 0 0 1 1 1 0 Thrombospondin type 3 repeat NAD_binding_6 PF08030.12 RUS91188.1 - 0.052 13.7 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain WD40 PF00400.32 RUS91189.1 - 6.5e-12 45.8 0.1 0.00047 20.9 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat NUFIP1 PF10453.9 RUS91190.1 - 4.6e-15 55.2 4.2 1.5e-14 53.6 4.2 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 RUS91190.1 - 0.00015 21.9 0.7 0.00034 20.8 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS91190.1 - 1 10.0 4.6 0.42 11.2 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type FoP_duplication PF13865.6 RUS91190.1 - 8.5 7.0 16.9 6.7 7.3 10.3 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ig_3 PF13927.6 RUS91191.1 - 3.5e-21 75.6 0.0 2.9e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 RUS91191.1 - 2.3e-19 69.3 0.0 6.4e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 RUS91191.1 - 1.4e-18 66.8 0.0 2e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 RUS91191.1 - 3.1e-15 56.3 0.0 2.6e-07 30.8 0.0 3.4 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 RUS91191.1 - 3.5e-10 40.1 0.0 6.6e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 RUS91191.1 - 1.9e-06 27.3 0.3 0.021 14.4 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain C2-set PF05790.15 RUS91191.1 - 0.0065 16.6 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 RUS91191.1 - 0.011 15.8 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 RUS91191.1 - 0.021 14.9 0.0 0.095 12.8 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 RUS91191.1 - 0.051 13.8 0.0 0.76 10.0 0.0 2.4 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Keratin_B2_2 PF13885.6 RUS91192.1 - 4.8e-19 68.0 18.9 0.13 12.2 2.5 7.9 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein Keratin_B2 PF01500.17 RUS91192.1 - 9.8e-13 48.4 32.8 1.1e+04 -3.7 32.8 5.4 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein PMG PF05287.12 RUS91192.1 - 0.0013 18.9 18.5 14 5.6 4.7 6.8 1 1 1 2 2 2 2 PMG protein Exo_endo_phos_2 PF14529.6 RUS91193.1 - 1.1e-08 34.9 1.2 1.1e-08 34.9 1.2 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase 4HBT PF03061.22 RUS91196.1 - 1.7e-06 28.3 0.2 0.0051 17.1 0.1 2.6 2 1 0 2 2 2 2 Thioesterase superfamily CofC PF01983.16 RUS91196.1 - 0.13 11.4 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like EF-hand_1 PF00036.32 RUS91198.1 - 2.1e-09 36.3 10.7 0.019 14.5 0.1 5.4 4 2 2 6 6 6 3 EF hand EF-hand_6 PF13405.6 RUS91198.1 - 4.2e-09 35.6 7.8 0.19 11.8 0.1 5.8 3 3 3 6 6 6 3 EF-hand domain EF-hand_7 PF13499.6 RUS91198.1 - 3.1e-07 30.7 4.8 0.014 15.8 0.2 4.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS91198.1 - 5.6e-05 22.5 12.8 0.0036 16.7 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 RUS91198.1 - 0.00019 21.2 5.3 1 9.3 0.0 4.2 3 1 1 4 4 4 1 EF-hand domain pair Dockerin_1 PF00404.18 RUS91198.1 - 0.0032 17.6 10.4 4.3 7.6 0.7 4.4 4 1 1 5 5 5 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 RUS91198.1 - 0.058 13.7 0.3 1.1 9.6 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Trypsin_2 PF13365.6 RUS91199.1 - 5.9e-08 33.7 0.1 9.4e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pyridoxal_deC PF00282.19 RUS91200.1 - 5.8e-106 354.4 1.1 1.5e-81 274.0 0.3 3.0 1 1 2 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 RUS91200.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase LRR_8 PF13855.6 RUS91202.1 - 7.2e-60 198.6 74.9 5.9e-14 51.6 4.1 11.8 6 4 5 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 RUS91202.1 - 3.3e-29 100.4 84.1 0.00012 22.4 2.9 15.5 8 5 8 17 17 17 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS91202.1 - 2.1e-18 66.5 10.5 5.3e-07 29.7 0.0 4.7 2 1 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) TIR PF01582.20 RUS91202.1 - 9.7e-16 58.1 0.0 1.7e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 RUS91202.1 - 3.3e-15 56.7 0.0 6.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 RUS91202.1 - 1.8e-13 50.4 24.8 0.051 13.1 0.1 8.5 4 2 4 9 9 9 6 Leucine-rich repeat LRR_1 PF00560.33 RUS91202.1 - 0.0015 18.8 52.9 9.6 7.2 0.1 15.3 18 0 0 18 18 18 2 Leucine Rich Repeat LRRNT PF01462.18 RUS91202.1 - 0.0052 16.4 0.3 0.0052 16.4 0.3 3.5 3 1 0 3 3 3 1 Leucine rich repeat N-terminal domain DUF4690 PF15756.5 RUS91202.1 - 0.16 12.6 1.1 8.3 7.1 0.4 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF1863 PF08937.11 RUS91202.1 - 0.17 12.2 0.3 1.3 9.3 0.3 2.1 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) MSSP PF03940.13 RUS91203.1 - 0.44 10.2 5.6 2.2 7.9 5.6 2.0 1 1 0 1 1 1 0 Male specific sperm protein DUF1079 PF06435.11 RUS91204.1 - 0.013 15.7 4.1 5 7.5 0.3 3.4 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) DUF4279 PF14106.6 RUS91204.1 - 0.24 11.6 3.3 21 5.3 0.0 3.8 2 1 1 4 4 4 0 Domain of unknown function (DUF4279) Aminotran_1_2 PF00155.21 RUS91205.1 - 2.7e-28 99.2 0.0 3.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 RUS91205.1 - 0.0031 16.4 0.0 0.0048 15.7 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 RUS91205.1 - 0.054 12.8 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase RabGAP-TBC PF00566.18 RUS91206.1 - 2.5e-52 177.7 0.3 2.5e-52 177.7 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6_N PF17675.1 RUS91206.1 - 0.0049 17.4 6.8 0.0049 17.4 6.8 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region UPF0242 PF06785.11 RUS91206.1 - 0.088 12.9 5.1 0.024 14.8 2.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 RUS91206.1 - 0.21 11.4 2.7 0.37 10.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PspB PF06667.12 RUS91206.1 - 6.1 7.0 5.8 1.5 9.0 2.1 1.9 2 0 0 2 2 2 0 Phage shock protein B Ank_2 PF12796.7 RUS91207.1 - 6.1e-17 62.0 0.0 7.6e-08 32.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91207.1 - 2.9e-16 59.6 0.3 4.6e-07 30.3 0.0 4.7 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 RUS91207.1 - 2.9e-11 43.3 1.2 0.0011 19.3 0.2 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 RUS91207.1 - 7e-11 41.4 2.3 0.082 13.5 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 RUS91207.1 - 2.6e-08 33.9 0.2 0.00034 20.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Proteasome PF00227.26 RUS91208.1 - 5e-57 192.5 0.0 8e-57 191.8 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 RUS91208.1 - 2.8e-10 39.7 0.1 4.9e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SSF PF00474.17 RUS91210.1 - 1.5e-34 119.6 14.5 1.5e-34 119.6 14.5 2.2 1 1 1 2 2 2 1 Sodium:solute symporter family Kunitz_legume PF00197.18 RUS91211.1 - 0.00026 21.0 7.9 0.79 9.6 0.7 3.4 1 1 3 4 4 4 4 Trypsin and protease inhibitor Adeno_E3_CR1 PF02440.15 RUS91211.1 - 0.0011 18.7 7.6 0.049 13.4 3.8 2.6 1 1 2 3 3 3 3 Adenovirus E3 region protein CR1 CopG_antitoxin PF12441.8 RUS91211.1 - 0.0057 17.2 10.5 7.3 7.2 1.3 4.6 1 1 4 5 5 5 1 CopG antitoxin of type II toxin-antitoxin system Molybdop_Fe4S4 PF04879.16 RUS91211.1 - 0.02 14.8 1.8 28 4.8 0.1 4.0 1 1 3 4 4 4 0 Molybdopterin oxidoreductase Fe4S4 domain DUF1447 PF07288.11 RUS91211.1 - 0.15 12.1 15.6 5.7 7.1 1.0 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1447) Efg1 PF10153.9 RUS91211.1 - 0.2 12.0 2.1 23 5.4 1.3 3.9 1 1 1 2 2 2 0 rRNA-processing protein Efg1 CsoS2_M PF12288.8 RUS91211.1 - 0.32 10.4 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region DUF3642 PF12182.8 RUS91211.1 - 0.33 11.3 12.3 5.5 7.3 1.8 2.8 1 1 1 2 2 2 0 Bacterial lipoprotein PBECR1 PF18809.1 RUS91211.1 - 0.93 10.2 7.7 26 5.5 2.1 3.1 1 1 3 4 4 4 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Cupredoxin_1 PF13473.6 RUS91211.1 - 1.1 9.4 8.7 11 6.2 1.8 2.8 1 1 1 2 2 2 0 Cupredoxin-like domain DUF3991 PF13154.6 RUS91211.1 - 5.5 7.4 10.7 8e+03 -2.7 10.7 4.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3991) PT PF04886.12 RUS91212.1 - 1.2e-26 92.0 154.6 1.8e+04 -16.2 74.7 8.2 1 1 1 2 2 2 0 PT repeat FlgT_N PF16548.5 RUS91212.1 - 2.3 8.8 47.6 95 3.7 0.4 5.6 1 1 1 3 3 3 0 Flagellar assembly protein T, N-terminal domain FXa_inhibition PF14670.6 RUS91213.1 - 4.8e-06 26.8 21.9 0.0099 16.1 6.9 2.6 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 RUS91213.1 - 0.014 15.1 1.7 0.054 13.3 1.7 2.0 1 0 0 1 1 1 0 Putative ephrin-receptor like cEGF PF12662.7 RUS91213.1 - 2.2 8.3 6.7 19 5.3 0.7 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like PHD PF00628.29 RUS91214.1 - 9.8e-13 47.8 8.2 3e-12 46.2 8.2 1.9 1 0 0 1 1 1 1 PHD-finger Bromodomain PF00439.25 RUS91214.1 - 0.00026 21.0 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Zf_RING PF16744.5 RUS91214.1 - 0.082 13.0 0.8 0.24 11.5 0.8 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 RUS91214.1 - 0.24 11.0 1.4 0.55 9.8 1.4 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 RUS91214.1 - 0.29 11.1 2.7 0.83 9.6 2.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 RUS91214.1 - 0.52 9.9 6.9 0.044 13.4 1.1 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DDT PF02791.17 RUS91215.1 - 1.4e-08 34.9 0.3 3.9e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 RUS91215.1 - 2.1e-07 30.3 0.1 4.2e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 RUS91215.1 - 0.00025 21.5 0.6 0.0023 18.4 0.0 2.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Ecm29 PF13001.7 RUS91215.1 - 0.012 14.3 1.4 0.022 13.4 0.1 1.8 2 0 0 2 2 2 0 Proteasome stabiliser XAP5 PF04921.14 RUS91215.1 - 0.1 12.4 3.3 0.17 11.7 3.3 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM176 PF14851.6 RUS91215.1 - 0.41 10.3 3.8 0.8 9.4 3.8 1.5 1 0 0 1 1 1 0 FAM176 family YlbD_coat PF14071.6 RUS91215.1 - 0.65 10.3 3.2 0.59 10.4 1.4 1.8 2 0 0 2 2 2 0 Putative coat protein NOA36 PF06524.12 RUS91215.1 - 3 7.1 7.0 4.8 6.4 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein MBD PF01429.19 RUS91216.1 - 6.1e-14 51.5 0.0 1.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain DUF2559 PF10832.8 RUS91217.1 - 0.00015 21.7 2.4 3 8.0 0.1 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF2559) gag-asp_proteas PF13975.6 RUS91217.1 - 0.0021 18.6 1.3 0.79 10.3 0.1 3.2 1 1 2 3 3 3 2 gag-polyprotein putative aspartyl protease Drf_FH1 PF06346.12 RUS91217.1 - 0.006 16.3 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 GBR2_CC PF18455.1 RUS91217.1 - 0.24 11.6 11.1 12 6.1 0.6 4.6 1 1 5 6 6 6 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF743 PF05332.11 RUS91217.1 - 0.76 9.9 8.3 4 7.5 1.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF743) GcnA_N PF18229.1 RUS91217.1 - 1 9.4 6.5 18 5.5 1.1 3.5 2 1 0 3 3 3 0 N-acetyl-beta-D-glucosaminidase N-terminal domain M_domain PF12938.7 RUS91217.1 - 1.7 8.4 18.5 7 6.4 2.0 3.3 1 1 2 3 3 3 0 M domain of GW182 SecE PF00584.20 RUS91218.1 - 9.7e-17 60.6 0.3 1.3e-16 60.2 0.3 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex MFS_1 PF07690.16 RUS91220.1 - 1.7e-56 191.7 24.5 2.2e-56 191.3 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS91220.1 - 9.2e-08 31.4 17.3 1.5e-06 27.3 17.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Pyridoxal_deC PF00282.19 RUS91222.1 - 4e-70 236.4 0.0 1.1e-66 225.1 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RUS91222.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RUS91222.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RUS91222.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2457 PF10446.9 RUS91223.1 - 0.017 14.3 6.3 0.027 13.6 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AGH PF17558.2 RUS91223.1 - 0.023 14.9 1.5 0.042 14.0 1.5 1.4 1 0 0 1 1 1 0 Androgenic gland hormone CENP-B_dimeris PF09026.10 RUS91223.1 - 0.037 14.4 13.0 0.068 13.6 13.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MPP6 PF10175.9 RUS91223.1 - 0.13 12.8 4.4 0.18 12.3 1.4 2.0 2 0 0 2 2 2 0 M-phase phosphoprotein 6 CDC45 PF02724.14 RUS91223.1 - 0.25 9.6 4.7 0.34 9.1 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS91223.1 - 1.3 8.3 8.8 2 7.7 8.8 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 RUS91223.1 - 2.1 8.8 15.3 0.41 11.0 11.8 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 RUS91223.1 - 2.3 8.2 6.7 0.21 11.6 2.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal BSP_II PF05432.11 RUS91223.1 - 2.3 7.8 11.8 0.14 11.9 6.3 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 RUS91223.1 - 3.8 8.2 11.2 6.3 7.5 11.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.6 RUS91223.1 - 9.3 5.9 9.0 1.5 8.4 5.2 1.6 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 RUS91223.1 - 9.4 4.3 10.3 7.4 4.6 8.4 1.6 2 0 0 2 2 2 0 Nop14-like family G-alpha PF00503.20 RUS91225.1 - 4.2e-85 286.0 0.3 5e-85 285.8 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RUS91225.1 - 9.4e-13 48.0 0.9 2.2e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS91225.1 - 1.9e-05 24.2 0.6 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RUS91225.1 - 0.00094 19.4 0.3 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RUS91225.1 - 0.013 15.1 0.4 23 4.6 0.0 3.3 3 1 0 3 3 3 0 Ras family LCE PF14672.6 RUS91226.1 - 0.039 14.5 0.1 0.039 14.5 0.1 2.0 2 0 0 2 2 2 0 Late cornified envelope DUF3109 PF11307.8 RUS91226.1 - 0.11 12.2 0.0 0.49 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3109) DUF678 PF05077.12 RUS91228.1 - 0.00013 22.0 3.5 43 4.3 0.0 5.9 1 1 4 6 6 6 0 Protein of unknown function (DUF678) PI3K_rbd PF00794.18 RUS91228.1 - 0.00023 21.3 4.9 11 6.3 0.1 4.1 1 1 6 7 7 7 7 PI3-kinase family, ras-binding domain DUF3388 PF11868.8 RUS91228.1 - 0.00062 19.2 0.3 38 3.6 0.0 4.9 1 1 7 8 8 8 0 Protein of unknown function (DUF3388) LktC PF06261.11 RUS91228.1 - 0.0091 15.9 12.5 23 4.9 0.6 4.8 1 1 4 5 5 5 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Cyc-maltodext_N PF09087.11 RUS91228.1 - 0.014 15.6 1.5 18 5.7 0.1 2.9 1 1 3 4 4 4 0 Cyclomaltodextrinase, N-terminal Mon2_C PF16206.5 RUS91228.1 - 0.021 13.0 1.8 40 2.2 0.0 3.9 1 1 8 9 9 9 0 C-terminal region of Mon2 protein Fea1 PF07692.11 RUS91228.1 - 0.04 13.0 0.1 86 2.0 0.0 3.8 1 1 5 6 6 6 0 Low iron-inducible periplasmic protein SWIRM-assoc_1 PF16495.5 RUS91228.1 - 1.2 9.1 14.4 1e+02 3.0 0.2 5.5 1 1 8 9 9 9 0 SWIRM-associated region 1 Spt20 PF12090.8 RUS91229.1 - 1.7 8.2 17.3 0.036 13.7 10.0 1.9 2 0 0 2 2 2 0 Spt20 family Homeodomain PF00046.29 RUS91231.1 - 5.2e-24 83.9 5.6 7.4e-24 83.4 5.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS91231.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 RUS91231.1 - 0.18 11.3 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez An_peroxidase PF03098.15 RUS91232.1 - 3.3e-30 105.2 0.1 3.6e-30 105.0 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase IQ PF00612.27 RUS91233.1 - 2e-11 42.6 12.9 0.0048 16.6 0.5 4.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif SAVED PF18145.1 RUS91233.1 - 0.012 15.4 0.0 0.083 12.7 0.0 2.1 1 1 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain SH3_9 PF14604.6 RUS91234.1 - 9.4e-11 41.4 0.1 1.4e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RUS91234.1 - 3.7e-07 29.7 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS91234.1 - 4.2e-06 26.3 0.4 1.1e-05 25.0 0.4 1.7 1 1 0 1 1 1 1 SH3 domain DUF3665 PF12427.8 RUS91234.1 - 5.4 6.8 8.3 0.17 11.6 1.9 1.9 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase bZIP_Maf PF03131.17 RUS91235.1 - 7.4e-17 61.7 3.4 7.4e-17 61.7 3.4 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 RUS91235.1 - 9.4e-06 25.6 7.8 3.8e-05 23.7 7.8 2.1 1 0 0 1 1 1 1 bZIP transcription factor CD225 PF04505.12 RUS91236.1 - 0.0021 18.2 0.3 0.0037 17.4 0.3 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DSS1_SEM1 PF05160.13 RUS91237.1 - 3.7e-23 81.3 19.6 6.8e-23 80.5 19.6 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family RVT_1 PF00078.27 RUS91237.1 - 4.7e-06 26.3 0.1 6.6e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2947 PF11163.8 RUS91237.1 - 0.35 10.7 6.8 0.15 11.9 4.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2947) Ribul_P_3_epim PF00834.19 RUS91238.1 - 3e-67 225.8 0.0 3.5e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 RUS91238.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family BAR PF03114.18 RUS91239.1 - 2.8e-24 86.1 1.0 2.8e-24 86.1 1.0 1.7 2 0 0 2 2 2 1 BAR domain TBCA PF02970.16 RUS91239.1 - 2.8 8.3 8.3 0.25 11.7 1.3 2.8 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF773 PF05600.12 RUS91241.1 - 5e-116 388.4 7.0 5.6e-116 388.3 7.0 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 HIP1_clath_bdg PF16515.5 RUS91241.1 - 0.013 16.1 10.5 0.061 13.9 0.1 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atx10homo_assoc PF09759.9 RUS91243.1 - 7.5e-13 48.4 0.1 3.9e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain RL10P_insert PF17777.1 RUS91243.1 - 0.003 17.5 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P DSL PF01414.19 RUS91245.1 - 3e-17 62.6 7.0 3e-17 62.6 7.0 2.3 2 0 0 2 2 2 1 Delta serrate ligand EGF_CA PF07645.15 RUS91245.1 - 1.6e-09 37.8 6.1 1.6e-09 37.8 6.1 2.5 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 RUS91245.1 - 4.1e-07 30.2 6.2 4.1e-07 30.2 6.2 3.2 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.7 RUS91245.1 - 0.00012 22.6 6.4 0.00012 22.6 6.4 3.5 5 0 0 5 5 5 1 Human growth factor-like EGF cEGF PF12662.7 RUS91245.1 - 0.00027 20.8 7.2 0.16 11.9 0.5 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_2 PF07974.13 RUS91245.1 - 0.00035 20.9 7.4 0.00035 20.9 7.4 3.2 2 1 0 2 2 2 1 EGF-like domain FXa_inhibition PF14670.6 RUS91245.1 - 0.013 15.7 7.4 0.013 15.7 7.4 2.9 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 RUS91245.1 - 0.053 13.7 6.3 0.053 13.7 6.3 2.9 1 1 1 2 2 2 0 EGF domain Laminin_EGF PF00053.24 RUS91245.1 - 0.25 11.5 17.8 12 6.2 3.9 2.9 1 1 1 2 2 2 0 Laminin EGF domain NAM-associated PF14303.6 RUS91246.1 - 0.003 18.3 1.4 0.004 17.9 1.4 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain EGF PF00008.27 RUS91246.1 - 0.027 14.8 3.5 0.043 14.1 3.5 1.3 1 0 0 1 1 1 0 EGF-like domain Med13_C PF06333.12 RUS91246.1 - 0.33 10.2 14.3 0.35 10.1 14.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 RUS91246.1 - 0.9 9.3 9.9 1.2 8.9 9.9 1.4 1 1 0 1 1 1 0 MID domain of medPIWI FSA_C PF10479.9 RUS91246.1 - 6.4 4.8 16.5 6.6 4.7 16.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Guanylate_cyc PF00211.20 RUS91248.1 - 4.5e-59 199.1 0.2 6.3e-59 198.7 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 RUS91248.1 - 1.8e-45 155.1 4.6 1.1e-43 149.3 4.6 2.2 1 1 0 1 1 1 1 Heme NO binding associated DUF3464 PF11947.8 RUS91248.1 - 0.15 11.8 1.9 0.23 11.2 0.5 2.0 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 LRR_6 PF13516.6 RUS91250.1 - 1.1e-18 65.6 22.4 0.00032 20.5 0.2 7.9 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 RUS91250.1 - 6.6e-05 22.9 3.0 7.9 7.5 0.0 6.0 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 RUS91250.1 - 0.0014 19.0 15.8 0.026 15.0 0.3 5.3 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) CARD PF00619.21 RUS91250.1 - 0.0082 16.2 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Caspase recruitment domain LRR_8 PF13855.6 RUS91250.1 - 1.1 9.0 18.8 0.55 10.0 1.3 5.1 3 2 2 5 5 5 0 Leucine rich repeat 7tm_1 PF00001.21 RUS91251.1 - 8.4e-23 81.0 0.9 1.6e-22 80.1 0.9 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EutH PF04346.12 RUS91251.1 - 0.053 12.7 3.6 0.086 12.0 3.6 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Lectin_C PF00059.21 RUS91252.1 - 4.3e-06 27.4 6.2 0.015 16.0 0.0 5.2 4 1 0 4 4 4 2 Lectin C-type domain DUF148 PF02520.17 RUS91252.1 - 1.6 8.8 7.9 20 5.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 Glyco_transf_92 PF01697.27 RUS91253.1 - 5.7e-25 88.4 0.0 1.2e-24 87.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RUS91253.1 - 0.002 18.6 0.0 0.0099 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 7tm_2 PF00002.24 RUS91255.1 - 3.5e-33 114.9 25.2 4.9e-33 114.4 25.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 RUS91255.1 - 2.9e-11 43.7 5.7 6.4e-11 42.6 5.7 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF687 PF05095.12 RUS91255.1 - 0.0041 15.7 0.1 0.0073 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF687) BicD PF09730.9 RUS91255.1 - 0.25 9.7 0.0 0.36 9.2 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF3446 PF11928.8 RUS91255.1 - 0.4 11.0 4.6 1.1 9.6 4.6 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain Hydrolase_4 PF12146.8 RUS91256.1 - 1.9e-59 200.8 0.0 2.5e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RUS91256.1 - 8.7e-08 32.1 0.3 0.00029 20.6 0.1 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 RUS91256.1 - 6e-05 22.8 0.0 9.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 RUS91256.1 - 0.00084 18.9 0.0 0.0074 15.8 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 RUS91256.1 - 0.0055 17.3 0.5 0.026 15.1 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 RUS91257.1 - 5.5e-10 39.4 0.1 0.0064 16.8 0.1 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RUS91257.1 - 3.5e-09 37.2 7.1 0.0091 16.8 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 RUS91257.1 - 3e-05 23.5 0.3 0.11 11.7 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain Frtz PF11768.8 RUS91257.1 - 0.00032 19.2 0.1 0.001 17.5 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PA-IIL PF07472.11 RUS91257.1 - 0.081 13.2 0.3 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) RNA_pol_Rpc4 PF05132.14 RUS91259.1 - 0.027 14.9 2.4 0.027 14.9 2.4 3.0 2 1 1 3 3 3 0 RNA polymerase III RPC4 EMC3_TMCO1 PF01956.16 RUS91260.1 - 3.5e-40 137.5 0.3 4.1e-40 137.3 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ig_3 PF13927.6 RUS91263.1 - 0.0067 17.0 0.1 0.054 14.1 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain DNA_pol_phi PF04931.13 RUS91263.1 - 0.45 8.6 6.7 0.71 7.9 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS91263.1 - 0.83 7.9 5.7 1.2 7.4 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 RUS91263.1 - 7.4 5.7 7.5 14 4.8 7.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rtt106_N PF18215.1 RUS91264.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain CCM2_C PF16545.5 RUS91266.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Lamprin PF06403.11 RUS91267.1 - 3.5 7.6 12.8 4.3 7.3 12.1 1.4 1 1 0 1 1 1 0 Lamprin Kunitz_BPTI PF00014.23 RUS91268.1 - 5.1e-69 228.4 56.1 6.4e-18 64.7 9.1 4.2 4 0 0 4 4 4 4 Kunitz/Bovine pancreatic trypsin inhibitor domain WW PF00397.26 RUS91268.1 - 0.39 10.8 5.6 6.3 7.0 0.1 3.5 3 0 0 3 3 3 0 WW domain TPR_2 PF07719.17 RUS91269.1 - 2.6e-09 36.5 4.3 0.02 15.0 1.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RUS91269.1 - 6.1e-07 29.0 2.6 0.54 10.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS91269.1 - 3.2e-06 27.5 8.1 0.67 10.9 0.5 4.9 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS91269.1 - 3.9e-06 26.4 0.0 1.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 RUS91269.1 - 2.2e-05 24.9 2.6 0.0013 19.2 0.0 3.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91269.1 - 5e-05 23.2 10.0 0.21 11.9 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RUS91269.1 - 7.7e-05 23.3 6.1 2.4 8.9 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 RUS91269.1 - 0.00041 20.5 6.4 0.33 11.4 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS91269.1 - 0.0042 17.3 7.1 0.88 9.9 0.2 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RUS91269.1 - 0.0059 16.5 2.0 31 4.9 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat FAT PF02259.23 RUS91269.1 - 0.018 14.3 0.0 3.9 6.6 0.0 3.0 2 1 0 3 3 3 0 FAT domain Tyr_Deacylase PF02580.16 RUS91270.1 - 1e-49 168.7 0.0 1.2e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Kin17_mid PF10357.9 RUS91270.1 - 0.083 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein FERM_M PF00373.18 RUS91271.1 - 1.1e-10 42.0 1.0 2.3e-10 40.9 1.0 1.6 1 0 0 1 1 1 1 FERM central domain RTP1_C1 PF10363.9 RUS91271.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 WH1 PF00568.23 RUS91272.1 - 1.4e-11 44.3 0.0 3.7e-10 39.7 0.0 2.6 3 0 0 3 3 3 1 WH1 domain DUF1676 PF07898.13 RUS91273.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2615 PF11027.8 RUS91273.1 - 0.035 14.3 0.5 0.035 14.3 0.5 3.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) Amnionless PF14828.6 RUS91274.1 - 2.2e-92 310.3 0.0 2.6e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Amnionless DUF3377 PF11857.8 RUS91274.1 - 0.18 11.7 0.7 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pkinase PF00069.25 RUS91275.1 - 3.4e-139 462.6 0.0 9.7e-71 238.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91275.1 - 1.5e-64 217.8 0.0 3.6e-31 108.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RUS91275.1 - 2.2e-12 46.9 0.0 1.6e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 RUS91275.1 - 4.1e-11 42.6 0.1 5.7e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS91275.1 - 9e-08 31.3 0.3 0.00028 19.8 0.0 3.5 4 0 0 4 4 4 2 Fungal protein kinase APH PF01636.23 RUS91275.1 - 1.4e-07 31.7 0.6 0.021 14.8 0.0 3.8 2 2 2 4 4 4 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 RUS91275.1 - 1.3e-06 29.0 0.3 8.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 RUS91275.1 - 0.00021 21.0 0.1 0.91 9.1 0.0 3.3 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RUS91275.1 - 0.00067 18.7 0.3 0.00067 18.7 0.3 2.8 3 0 0 3 3 3 2 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 RUS91275.1 - 0.05 13.1 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Galactosyl_T PF01762.21 RUS91277.1 - 1.5e-42 145.7 0.2 3.7e-42 144.4 0.2 1.6 1 1 0 1 1 1 1 Galactosyltransferase Cornifin PF02389.15 RUS91279.1 - 1e-08 35.4 5.1 5.4e-06 26.7 1.0 1.9 1 1 1 2 2 2 2 Cornifin (SPRR) family Galactosyl_T PF01762.21 RUS91280.1 - 9.1e-45 152.9 0.0 2.5e-44 151.5 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase LMBR1 PF04791.16 RUS91281.1 - 0.99 8.2 8.2 1.5 7.6 8.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GCN5L1 PF06320.13 RUS91281.1 - 1.5 8.9 12.2 0.75 10.0 5.5 2.9 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Phage_GPO PF05929.11 RUS91281.1 - 4.5 6.8 8.7 13 5.3 8.7 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 RUS91281.1 - 6.1 5.6 25.4 0.88 8.4 8.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 RUS91281.1 - 6.3 7.0 31.2 0.65 10.2 1.6 2.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 RCR PF12273.8 RUS91282.1 - 0.15 12.7 0.3 0.28 11.8 0.1 1.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red HOOK PF05622.12 RUS91283.1 - 7.4e-29 100.4 62.6 7.4e-29 100.4 62.6 4.5 1 1 3 4 4 4 3 HOOK protein CENP-F_leu_zip PF10473.9 RUS91283.1 - 0.00069 19.7 19.8 0.00069 19.7 19.8 11.5 1 1 8 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 RUS91283.1 - 0.0008 18.8 38.1 0.0019 17.6 14.8 11.1 2 2 9 12 12 12 5 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 RUS91283.1 - 0.012 16.2 11.3 0.012 16.2 11.3 12.0 2 2 10 12 12 12 0 Apg6 coiled-coil region YabA PF06156.13 RUS91283.1 - 0.018 15.7 5.5 0.018 15.7 5.5 15.8 2 2 12 15 15 15 0 Initiation control protein YabA HALZ PF02183.18 RUS91283.1 - 0.08 13.2 0.2 0.043 14.0 0.9 21.5 18 6 5 23 23 23 0 Homeobox associated leucine zipper TrmO_C PF18389.1 RUS91283.1 - 7.1 6.8 12.2 1.2 9.3 0.1 5.3 5 0 0 5 5 5 0 TrmO C-terminal domain RAP PF08373.10 RUS91285.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 0 RAP domain Reticulon PF02453.17 RUS91287.1 - 0.059 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Reticulon RNA_pol_Rpc4 PF05132.14 RUS91288.1 - 0.00022 21.7 6.0 0.0003 21.2 6.0 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Na_trans_assoc PF06512.13 RUS91288.1 - 0.00058 20.2 14.0 0.00062 20.1 14.0 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated CobT PF06213.12 RUS91288.1 - 0.0023 17.4 39.4 0.0034 16.8 39.4 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 RUS91288.1 - 0.0027 15.7 14.4 0.003 15.6 14.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Nop14 PF04147.12 RUS91288.1 - 0.013 13.7 41.8 0.016 13.5 41.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2828 PF11443.8 RUS91288.1 - 0.021 12.9 8.2 0.027 12.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PPL5 PF18168.1 RUS91288.1 - 0.023 14.0 7.7 0.031 13.6 7.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 BUD22 PF09073.10 RUS91288.1 - 0.029 13.7 35.6 0.036 13.4 35.6 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 RUS91288.1 - 0.038 12.1 12.0 0.046 11.9 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 RUS91288.1 - 0.094 12.5 14.9 0.2 11.4 14.9 1.5 1 0 0 1 1 1 0 Connexin Mpp10 PF04006.12 RUS91288.1 - 0.095 11.1 43.0 0.11 10.9 43.0 1.1 1 0 0 1 1 1 0 Mpp10 protein SID-1_RNA_chan PF13965.6 RUS91288.1 - 0.12 10.8 6.6 0.16 10.4 6.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Merozoite_SPAM PF07133.11 RUS91288.1 - 0.13 12.3 66.3 0.17 11.8 66.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 RUS91288.1 - 0.2 10.4 14.4 0.23 10.2 14.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 RUS91288.1 - 0.26 11.1 30.0 0.34 10.7 30.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 RUS91288.1 - 0.28 11.3 7.9 0.52 10.4 7.9 1.5 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 RUS91288.1 - 0.29 10.3 11.6 0.35 10.0 11.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 RUS91288.1 - 0.43 9.3 19.0 0.54 9.0 19.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 RUS91288.1 - 0.48 9.4 14.2 0.7 8.8 14.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 RUS91288.1 - 0.54 10.0 13.2 0.69 9.7 13.2 1.2 1 0 0 1 1 1 0 AAA domain CSG2 PF16965.5 RUS91288.1 - 0.93 8.4 4.9 1.3 7.9 4.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 RUS91288.1 - 1.5 7.6 8.8 2.2 7.1 8.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SDA1 PF05285.12 RUS91288.1 - 1.6 8.1 44.3 2.3 7.6 44.3 1.1 1 0 0 1 1 1 0 SDA1 Mem_trans PF03547.18 RUS91288.1 - 1.9 6.8 6.8 2.5 6.4 6.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DcuC PF03606.15 RUS91288.1 - 2.1 6.7 3.1 1.2 7.4 0.1 2.1 2 1 1 3 3 3 0 C4-dicarboxylate anaerobic carrier DUF2457 PF10446.9 RUS91288.1 - 2.2 7.3 43.6 4.5 6.3 43.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 RUS91288.1 - 3.5 6.3 23.1 5.1 5.7 23.1 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 RUS91288.1 - 3.6 6.5 12.9 1.1 8.3 10.4 1.4 2 0 0 2 2 1 0 CLN3 protein RPN2_C PF18004.1 RUS91288.1 - 4.1 7.3 39.9 14 5.6 39.9 1.8 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Drc1-Sld2 PF11719.8 RUS91288.1 - 4.7 6.7 24.0 7.4 6.0 24.0 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein DNA_pol_phi PF04931.13 RUS91288.1 - 4.7 5.2 55.0 6.1 4.8 55.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIP PF07454.11 RUS91288.1 - 5.2 6.4 24.0 9.1 5.6 24.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Raftlin PF15250.6 RUS91288.1 - 6.2 5.4 14.0 7.4 5.2 14.0 1.1 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 RUS91288.1 - 8.3 5.3 14.6 10 5.0 14.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Sigma_1s PF02454.16 RUS91289.1 - 0.073 13.1 1.9 0.097 12.7 1.9 1.2 1 0 0 1 1 1 0 Sigma 1s protein HCMVantigenic_N PF12154.8 RUS91290.1 - 2.3 8.4 8.6 12 6.2 0.6 2.8 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Anp1 PF03452.14 RUS91291.1 - 1e-07 31.7 0.3 0.00049 19.6 0.1 3.1 2 1 1 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 RUS91291.1 - 0.00035 21.4 0.0 0.00092 20.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Citrate_bind PF16114.5 RUS91291.1 - 0.2 11.1 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Sulfotransfer_1 PF00685.27 RUS91292.1 - 1.4e-24 87.0 0.0 1.8e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS91292.1 - 8.6e-13 49.2 0.2 2.6e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS91292.1 - 0.021 14.7 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS91293.1 - 3e-25 89.2 0.1 4e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS91293.1 - 2.6e-14 54.1 0.1 3.2e-08 34.2 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 RUS91293.1 - 0.0087 16.0 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family MMS1_N PF10433.9 RUS91294.1 - 9.8e-108 360.9 0.0 9.1e-107 357.7 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RUS91294.1 - 1.7e-79 267.5 0.2 5.7e-79 265.7 0.1 1.9 2 0 0 2 2 2 1 CPSF A subunit region SPT2 PF08243.11 RUS91296.1 - 2.8e-22 79.4 17.5 2.8e-22 79.4 17.5 7.8 5 2 0 6 6 6 1 SPT2 chromatin protein PRAS PF15798.5 RUS91297.1 - 1.4e-10 41.8 0.3 1.4e-10 41.8 0.3 2.1 2 2 1 3 3 3 1 Proline-rich AKT1 substrate 1 Orbi_VP5 PF00901.17 RUS91297.1 - 0.083 11.3 0.3 0.12 10.7 0.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 B277 PF17623.2 RUS91297.1 - 0.51 9.4 3.4 0.74 8.8 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function Death PF00531.22 RUS91298.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Death domain SEFIR PF08357.11 RUS91298.1 - 8.6e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 SEFIR domain COMM_domain PF07258.14 RUS91300.1 - 5.7e-22 77.6 0.0 1.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 COMM domain DNA_mis_repair PF01119.19 RUS91300.1 - 0.0035 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF2443 PF10398.9 RUS91300.1 - 0.085 12.9 0.1 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) MADF_DNA_bdg PF10545.9 RUS91301.1 - 1.7e-18 66.7 0.4 1.7e-18 66.7 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BESS PF02944.20 RUS91301.1 - 6.2e-06 25.9 0.6 4.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 BESS motif Myb_DNA-bind_6 PF13921.6 RUS91301.1 - 0.029 14.6 0.1 0.071 13.4 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1517 PF07466.11 RUS91301.1 - 0.049 13.7 1.4 0.31 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) HTH_AsnC-type PF13404.6 RUS91301.1 - 0.11 12.4 0.3 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPH PF13868.6 RUS91301.1 - 0.15 10.5 6.9 0.57 8.6 3.9 2.0 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain TIP49 PF06068.13 RUS91303.1 - 3.8e-162 539.4 5.2 5.2e-162 539.0 5.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RUS91303.1 - 6e-29 100.0 1.0 1.7e-28 98.5 1.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 RUS91303.1 - 2.2e-09 37.9 2.0 6.4e-06 26.6 0.1 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 RUS91303.1 - 8e-07 28.7 0.3 1.7e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 RUS91303.1 - 8.9e-07 28.8 0.7 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RUS91303.1 - 9.3e-06 25.7 0.3 0.0066 16.5 0.0 3.3 2 1 2 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RUS91303.1 - 3.4e-05 24.1 0.5 0.048 13.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS91303.1 - 4.3e-05 24.0 0.3 0.00047 20.6 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 RUS91303.1 - 0.00035 20.3 0.5 0.5 10.1 0.1 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 RUS91303.1 - 0.00046 19.6 1.2 0.02 14.3 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 RUS91303.1 - 0.00076 19.1 0.1 0.003 17.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RUS91303.1 - 0.00099 19.5 6.0 0.0025 18.2 3.3 2.6 2 1 0 2 2 1 1 AAA domain ATPase PF06745.13 RUS91303.1 - 0.0065 15.8 2.4 0.014 14.8 2.3 1.6 1 1 0 1 1 1 1 KaiC AAA_23 PF13476.6 RUS91303.1 - 0.0076 16.8 1.5 0.016 15.7 1.5 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RUS91303.1 - 0.012 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 RUS91303.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 RUS91303.1 - 0.016 14.5 0.4 0.039 13.2 0.4 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 RUS91303.1 - 0.047 13.5 1.7 0.38 10.5 1.7 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS91303.1 - 0.067 12.7 0.5 0.37 10.3 0.0 2.3 2 1 1 3 3 3 0 P-loop containing dynein motor region TsaE PF02367.17 RUS91303.1 - 0.1 12.6 1.6 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RUS91303.1 - 0.13 11.9 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 RUS91303.1 - 0.19 11.7 1.8 5.8 6.9 1.8 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit GATase PF00117.28 RUS91303.1 - 0.34 10.6 1.3 2.5 7.8 1.3 2.1 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Ku_N PF03731.15 RUS91305.1 - 1.6e-48 165.3 1.0 2.4e-48 164.8 1.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 RUS91305.1 - 2.9e-47 161.0 0.0 4.5e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA PF00092.28 RUS91305.1 - 1.4e-05 25.4 0.7 0.00029 21.2 0.7 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain SAP PF02037.27 RUS91305.1 - 7.1e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 RUS91305.1 - 0.0054 17.4 0.0 0.02 15.6 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm LIM PF00412.22 RUS91306.1 - 5.8e-12 45.7 3.9 9.3e-12 45.0 3.9 1.3 1 0 0 1 1 1 1 LIM domain DUF4167 PF13763.6 RUS91306.1 - 0.014 15.5 0.0 15 5.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4167) HHH_2 PF12826.7 RUS91306.1 - 7.5 6.7 5.2 72 3.6 0.1 4.0 5 0 0 5 5 5 0 Helix-hairpin-helix motif HTH_psq PF05225.16 RUS91307.1 - 2.9e-08 33.3 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 RUS91307.1 - 0.00071 19.3 0.0 0.0049 16.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 RUS91307.1 - 0.0084 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 RUS91307.1 - 0.0087 15.6 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding PapB PF03333.13 RUS91307.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Trypan_PARP PF05887.11 RUS91307.1 - 0.18 11.8 2.8 0.32 11.0 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BSP_II PF05432.11 RUS91307.1 - 0.23 11.1 5.0 0.35 10.5 5.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DDE_1 PF03184.19 RUS91308.1 - 6.3e-16 58.5 0.0 8.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease FtsJ PF01728.19 RUS91310.1 - 7.1e-53 179.3 0.0 9.1e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 RUS91310.1 - 0.00036 20.4 0.1 0.0043 16.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS91310.1 - 0.048 13.5 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Flavin_Reduct PF01613.18 RUS91311.1 - 1.7e-35 122.4 0.0 2.5e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain NYN PF01936.18 RUS91312.1 - 6e-17 62.5 0.2 1.5e-16 61.2 0.2 1.6 1 0 0 1 1 1 1 NYN domain Limkain-b1 PF11608.8 RUS91312.1 - 7.9e-17 61.1 0.0 1.3e-15 57.2 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_1 PF00076.22 RUS91312.1 - 0.0008 19.2 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIN_4 PF13638.6 RUS91312.1 - 0.11 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 PIN domain Trypsin PF00089.26 RUS91313.1 - 6.9e-64 215.7 0.1 1e-63 215.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS91313.1 - 1.2e-09 39.2 0.0 1.2e-09 39.2 0.0 1.8 2 0 0 2 2 1 1 Trypsin-like peptidase domain PAF PF15715.5 RUS91313.1 - 0.00036 21.1 5.5 0.00066 20.3 5.5 1.4 1 0 0 1 1 1 1 PCNA-associated factor histone like domain SPX PF03105.19 RUS91313.1 - 0.0059 16.6 0.8 0.006 16.5 0.8 1.1 1 0 0 1 1 1 1 SPX domain AF-4 PF05110.13 RUS91313.1 - 0.025 12.7 21.3 0.033 12.3 21.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1986 PF09342.11 RUS91313.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Apt1 PF10351.9 RUS91313.1 - 0.054 12.4 5.1 0.07 12.0 5.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 RUS91313.1 - 0.082 12.9 11.1 0.13 12.2 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 RUS91313.1 - 0.27 9.8 9.6 0.35 9.4 9.6 1.1 1 0 0 1 1 1 0 Macoilin family Sporozoite_P67 PF05642.11 RUS91313.1 - 0.62 8.1 6.4 0.87 7.6 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ANAPC1 PF12859.7 RUS91313.1 - 1.1 9.9 11.4 2.2 8.9 11.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 AT_hook PF02178.19 RUS91313.1 - 1.7 8.8 5.0 5.5 7.2 5.0 1.9 1 0 0 1 1 1 0 AT hook motif Lung_7-TM_R PF06814.13 RUS91314.1 - 0.0022 17.3 4.3 0.0037 16.5 4.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor TFIIA PF03153.13 RUS91314.1 - 0.011 15.7 20.5 0.015 15.3 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.6 RUS91314.1 - 0.53 11.2 0.0 0.53 11.2 0.0 3.9 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SUR7 PF06687.12 RUS91314.1 - 0.81 9.3 5.6 1.6 8.3 5.6 1.5 1 0 0 1 1 1 0 SUR7/PalI family US6 PF17616.2 RUS91314.1 - 0.91 9.5 2.5 1.9 8.5 2.5 1.5 1 0 0 1 1 1 0 Viral unique short region 6 Fibrinogen_C PF00147.18 RUS91316.1 - 9.9e-57 192.3 4.9 1.8e-56 191.4 4.9 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS91316.1 - 5e-08 33.0 5.7 1.1e-05 25.4 5.7 2.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 RUS91316.1 - 2.6e-05 24.3 14.7 0.021 14.9 4.1 3.8 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 RUS91316.1 - 0.0043 17.0 2.8 2.8 7.9 0.1 3.5 2 1 1 3 3 3 1 Apolipoprotein O Cob_adeno_trans PF01923.18 RUS91316.1 - 0.0069 16.5 1.6 0.053 13.7 0.5 2.5 1 1 1 2 2 2 1 Cobalamin adenosyltransferase Exonuc_VII_L PF02601.15 RUS91316.1 - 0.033 13.8 8.8 0.2 11.2 8.8 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 RUS91316.1 - 0.082 13.1 16.2 0.59 10.3 6.8 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 RUS91316.1 - 0.11 13.1 9.2 10 6.7 0.1 3.5 2 1 0 2 2 2 0 YtxH-like protein OmpH PF03938.14 RUS91316.1 - 0.11 12.8 5.8 0.37 11.1 4.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 RUS91316.1 - 0.14 12.2 17.6 0.057 13.5 4.2 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) bMG10 PF17973.1 RUS91316.1 - 0.17 12.1 0.6 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF4164 PF13747.6 RUS91316.1 - 0.18 12.1 6.9 0.55 10.5 4.6 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) CENP-K PF11802.8 RUS91316.1 - 0.19 11.3 8.8 0.61 9.6 8.2 2.0 1 1 1 2 2 2 0 Centromere-associated protein K ApoLp-III PF07464.11 RUS91316.1 - 0.21 11.7 14.1 1.6 8.9 0.8 3.3 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Ran-binding PF05508.11 RUS91316.1 - 0.31 10.0 12.9 0.069 12.1 4.9 2.3 1 1 1 2 2 2 0 RanGTP-binding protein Prominin PF05478.11 RUS91316.1 - 0.31 8.9 13.8 0.74 7.7 10.4 2.0 1 1 1 2 2 2 0 Prominin DUF3552 PF12072.8 RUS91316.1 - 0.32 10.4 6.7 0.6 9.5 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CdvA PF18822.1 RUS91316.1 - 0.35 10.7 9.1 1.4 8.8 2.6 3.3 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF1640 PF07798.11 RUS91316.1 - 0.62 10.1 16.0 2.6 8.0 7.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1640) DUF1451 PF07295.11 RUS91316.1 - 0.81 9.7 6.9 1.2 9.2 4.3 2.4 1 1 1 2 2 2 0 Zinc-ribbon containing domain FAM184 PF15665.5 RUS91316.1 - 0.89 9.3 8.1 1.4 8.7 3.7 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Flagellin_N PF00669.20 RUS91316.1 - 0.98 9.5 0.0 0.98 9.5 0.0 3.9 3 1 2 5 5 5 0 Bacterial flagellin N-terminal helical region DUF5082 PF16888.5 RUS91316.1 - 1 9.7 14.8 0.3 11.4 1.9 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) FAP206 PF12018.8 RUS91316.1 - 1.1 8.7 5.0 3.9 6.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF4407 PF14362.6 RUS91316.1 - 1.3 8.3 7.1 3.8 6.8 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 RUS91316.1 - 1.5 8.5 12.4 19 5.0 0.4 3.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain KxDL PF10241.9 RUS91316.1 - 1.8 8.9 7.0 7.7 6.9 0.2 3.7 2 1 2 4 4 4 0 Uncharacterized conserved protein DUF4208 PF13907.6 RUS91316.1 - 2 8.9 7.0 4.1 7.9 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) Syntaxin PF00804.25 RUS91316.1 - 2 8.0 11.7 1.7 8.3 7.4 2.4 1 1 0 2 2 2 0 Syntaxin Occludin_ELL PF07303.13 RUS91316.1 - 2.5 8.9 5.2 24 5.7 0.1 3.4 1 1 2 4 4 4 0 Occludin homology domain Spc7 PF08317.11 RUS91316.1 - 3 6.6 13.2 1.7 7.4 10.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein BshC PF10079.9 RUS91316.1 - 3.3 6.3 8.5 2 7.1 4.5 2.1 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC GP41 PF00517.17 RUS91316.1 - 3.6 7.4 5.8 5.8 6.8 0.7 2.4 1 1 1 2 2 2 0 Retroviral envelope protein Rx_N PF18052.1 RUS91316.1 - 3.8 7.8 7.0 6 7.2 1.1 3.3 2 1 2 4 4 3 0 Rx N-terminal domain Muted PF14942.6 RUS91316.1 - 4 7.8 16.4 0.2 12.0 2.6 3.4 2 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 RUS91316.1 - 5.4 7.7 6.7 32 5.2 4.9 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Fzo_mitofusin PF04799.13 RUS91316.1 - 9 5.8 13.2 0.32 10.5 1.6 3.6 2 1 2 4 4 4 0 fzo-like conserved region zf-CCCH_3 PF15663.5 RUS91317.1 - 0.34 11.1 3.5 0.71 10.1 3.5 1.7 1 1 0 1 1 1 0 Zinc-finger containing family TFIIA PF03153.13 RUS91317.1 - 0.35 10.8 19.1 0.38 10.7 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_PH PF01138.21 RUS91318.1 - 8.6e-37 126.6 0.0 1.5e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RUS91318.1 - 0.025 14.6 0.6 0.06 13.4 0.1 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 NmrA PF05368.13 RUS91320.1 - 5.1e-27 94.9 0.0 5.9e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RUS91320.1 - 3.4e-18 66.2 0.0 4.4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RUS91320.1 - 7.6e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RUS91320.1 - 0.00025 20.1 0.0 0.00033 19.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 RUS91320.1 - 0.0046 17.4 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1363 PF07101.11 RUS91320.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1363) Neur_chan_LBD PF02931.23 RUS91321.1 - 6.6e-41 140.1 3.7 1e-18 67.6 0.3 4.6 2 2 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS91321.1 - 1.6e-25 90.5 9.9 1.6e-25 90.5 9.9 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Trypsin PF00089.26 RUS91322.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin 7tm_1 PF00001.21 RUS91323.1 - 3.2e-17 62.7 20.7 4e-17 62.4 20.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91323.1 - 0.01 15.2 18.6 0.024 14.0 18.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS91323.1 - 0.098 12.3 20.6 0.013 15.2 13.5 2.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx F-box PF00646.33 RUS91324.1 - 0.00035 20.4 0.7 0.00077 19.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain ABC2_membrane PF01061.24 RUS91325.1 - 7.5e-36 123.5 25.5 7.5e-36 123.5 25.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RUS91325.1 - 4.6e-21 75.8 0.0 8.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RUS91325.1 - 2.1e-07 31.0 0.4 0.01 15.6 0.3 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RUS91325.1 - 7.7e-07 28.8 0.1 0.00098 18.6 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 RUS91325.1 - 8.4e-06 25.1 27.5 8.4e-06 25.1 27.5 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 RUS91325.1 - 4.8e-05 24.0 0.1 0.00011 22.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RUS91325.1 - 0.0019 17.9 0.1 0.0059 16.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS91325.1 - 0.0054 16.6 0.1 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 RUS91325.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Pkinase PF00069.25 RUS91326.1 - 1.7e-56 191.5 0.0 2.2e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91326.1 - 1.5e-39 135.9 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS91326.1 - 5.2e-07 29.3 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 RUS91326.1 - 0.00022 20.4 0.2 0.00061 18.9 0.1 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 RUS91326.1 - 0.00058 18.9 0.0 0.00096 18.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS91326.1 - 0.0068 15.2 0.0 0.033 13.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 RUS91326.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SIS PF01380.22 RUS91327.1 - 5.8e-59 197.6 0.1 4.1e-33 114.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RUS91327.1 - 8.1e-17 61.7 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RUS91327.1 - 2.5e-13 50.0 0.0 5.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RUS91327.1 - 3.3e-06 26.2 0.1 7.8e-06 25.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 RUS91327.1 - 0.00096 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RUS91327.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 SIS domain DUF2529 PF10740.9 RUS91327.1 - 0.12 12.1 0.0 0.64 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2529) VWA PF00092.28 RUS91328.1 - 2.3e-20 73.5 4.0 7.4e-19 68.7 1.2 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS91328.1 - 5.1e-12 46.4 1.7 6.2e-11 42.9 0.2 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain TMEM214 PF10151.9 RUS91328.1 - 0.0017 16.9 12.4 0.0021 16.6 12.4 1.1 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator PS_pyruv_trans PF04230.13 RUS91328.1 - 0.003 17.5 0.3 0.01 15.7 0.2 1.7 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase DUF4770 PF15994.5 RUS91328.1 - 0.0058 16.9 6.5 0.007 16.6 6.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) Renin_r PF07850.14 RUS91328.1 - 0.021 15.4 0.2 0.066 13.8 0.2 1.8 1 0 0 1 1 1 0 Renin receptor-like protein SpoIIP PF07454.11 RUS91328.1 - 0.028 13.9 8.1 0.036 13.5 8.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 RUS91328.1 - 0.086 11.6 2.7 0.092 11.5 2.7 1.2 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 RUS91328.1 - 0.11 10.7 4.6 0.14 10.4 4.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATG11 PF10377.9 RUS91328.1 - 0.13 12.3 9.9 0.31 11.1 9.9 1.6 1 0 0 1 1 1 0 Autophagy-related protein 11 Zip PF02535.22 RUS91328.1 - 0.15 11.2 0.3 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 RUS91328.1 - 0.19 12.0 24.1 0.27 11.6 24.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Gti1_Pac2 PF09729.9 RUS91328.1 - 0.22 11.6 9.8 0.32 11.1 9.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family MDM10 PF12519.8 RUS91328.1 - 0.22 10.3 6.1 0.29 9.9 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SR-25 PF10500.9 RUS91328.1 - 0.29 10.7 37.9 0.59 9.7 37.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.12 RUS91328.1 - 0.36 10.1 19.1 0.53 9.6 19.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SRP-alpha_N PF04086.13 RUS91328.1 - 0.48 10.3 18.8 0.71 9.7 18.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RPN2_C PF18004.1 RUS91328.1 - 0.52 10.2 23.8 0.72 9.7 23.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain YL1 PF05764.13 RUS91328.1 - 0.99 9.5 24.4 1.4 9.0 24.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RUS91328.1 - 1.2 7.4 11.7 1.7 6.9 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein hDGE_amylase PF14701.6 RUS91328.1 - 1.4 7.9 8.5 1.8 7.5 8.5 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF1764 PF08576.10 RUS91328.1 - 1.4 9.8 22.2 2.3 9.2 22.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CPSF100_C PF13299.6 RUS91328.1 - 1.9 8.7 12.7 2.9 8.1 12.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LicD PF04991.13 RUS91328.1 - 1.9 8.5 13.2 2.7 8.0 13.2 1.3 1 0 0 1 1 1 0 LicD family FancD2 PF14631.6 RUS91328.1 - 2 5.7 11.0 2.6 5.3 11.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PPL5 PF18168.1 RUS91328.1 - 2.6 7.3 13.9 3.7 6.7 13.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF3807 PF12720.7 RUS91328.1 - 2.8 8.2 20.0 4 7.7 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 RUS91328.1 - 2.8 7.7 19.4 3.8 7.2 19.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 RUS91328.1 - 3.7 6.2 14.4 5.4 5.7 14.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 RUS91328.1 - 5.1 6.8 16.0 6.9 6.4 16.0 1.2 1 0 0 1 1 1 0 Connexin MDM1 PF15501.6 RUS91328.1 - 5.4 6.1 21.3 7.3 5.6 21.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Jak1_Phl PF17887.1 RUS91328.1 - 5.8 6.9 17.9 10 6.1 17.9 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain RNA_pol_Rpc4 PF05132.14 RUS91328.1 - 6.2 7.2 16.8 11 6.4 16.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 RUS91328.1 - 6.2 6.3 18.5 10 5.6 18.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2828 PF11443.8 RUS91328.1 - 6.8 4.7 16.3 8.6 4.3 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) VWA PF00092.28 RUS91329.1 - 4.6e-06 27.0 0.0 5.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS91329.1 - 0.12 13.1 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain PMP22_Claudin PF00822.20 RUS91331.1 - 0.0012 18.7 0.8 0.0054 16.6 0.8 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family CoatB PF10389.9 RUS91331.1 - 0.28 11.0 0.8 0.56 10.1 0.8 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B Peptidase_M16_C PF05193.21 RUS91332.1 - 6.7e-13 49.1 0.0 1.3e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RUS91332.1 - 1.1e-06 28.8 0.0 3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 RUS91332.1 - 0.0007 18.8 0.9 0.0007 18.8 0.9 3.0 3 1 0 3 3 3 1 Peptidase M16C associated STIL_N PF15253.6 RUS91333.1 - 0.24 10.3 2.3 0.17 10.8 0.6 1.6 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus DUF3391 PF11871.8 RUS91334.1 - 2.6 8.6 5.6 0.89 10.1 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) PTEN_C2 PF10409.9 RUS91335.1 - 8.4e-31 106.5 0.0 8.4e-31 106.5 0.0 2.4 3 1 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 RUS91335.1 - 0.00016 21.5 0.0 0.00016 21.5 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain NIBRIN_BRCT_II PF16508.5 RUS91335.1 - 0.077 13.3 4.6 0.24 11.7 4.6 1.8 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein U3snoRNP10 PF12397.8 RUS91335.1 - 0.19 12.1 0.6 0.42 11.0 0.6 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 ELO PF01151.18 RUS91340.1 - 1.2e-64 218.2 21.5 1.6e-64 217.8 21.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF782 PF05614.11 RUS91340.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) Pkinase_Tyr PF07714.17 RUS91341.1 - 4.3e-46 157.3 0.0 1.3e-35 123.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase I-set PF07679.16 RUS91341.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS91341.1 - 3.8e-13 49.8 0.1 3.8e-13 49.8 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Pkinase PF00069.25 RUS91341.1 - 2e-11 43.8 0.0 1e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 RUS91341.1 - 3.1e-11 43.4 0.1 6.8e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 RUS91341.1 - 1.4e-06 28.9 2.1 3.3e-06 27.7 2.1 1.6 1 0 0 1 1 1 1 Fz domain ig PF00047.25 RUS91341.1 - 6.7e-06 26.2 0.1 1.9e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS91341.1 - 0.00023 21.3 0.1 0.0044 17.2 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS91341.1 - 0.026 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_4 PF16680.5 RUS91341.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain 7tm_1 PF00001.21 RUS91342.1 - 8.1e-49 166.3 18.2 1.2e-48 165.8 18.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 RUS91342.1 - 1.2e-10 41.6 7.5 1.2e-10 41.6 7.5 1.6 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 RUS91342.1 - 1.7e-06 27.8 16.1 7.2e-06 25.8 15.8 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-CHY PF05495.12 RUS91343.1 - 4.7e-19 68.7 23.0 4.7e-19 68.7 23.0 4.3 2 1 0 3 3 2 1 CHY zinc finger zinc_ribbon_6 PF14599.6 RUS91343.1 - 1.2e-17 63.7 5.7 1.2e-17 63.7 5.7 3.9 3 1 1 4 4 1 1 Zinc-ribbon zf-RING_2 PF13639.6 RUS91343.1 - 2.5e-09 37.3 5.4 2.5e-09 37.3 5.4 5.6 3 2 2 5 5 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 RUS91343.1 - 3.5e-06 26.7 6.4 3.5e-06 26.7 6.4 5.7 6 1 0 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS91343.1 - 4.5e-05 23.3 5.3 4.5e-05 23.3 5.3 6.4 3 2 2 5 5 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RUS91343.1 - 6.2e-05 22.8 2.8 6.2e-05 22.8 2.8 5.9 3 1 2 5 5 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS91343.1 - 0.00012 22.1 4.6 0.00012 22.1 4.6 5.8 4 2 2 6 6 4 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 RUS91343.1 - 0.00014 21.6 2.5 0.00014 21.6 2.5 5.6 5 1 1 6 6 4 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 RUS91343.1 - 0.00045 19.8 1.8 0.00045 19.8 1.8 5.5 4 1 1 5 5 5 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RUS91343.1 - 0.0015 18.4 1.4 0.0015 18.4 1.4 6.2 4 3 2 6 6 4 2 Prokaryotic RING finger family 4 PHD PF00628.29 RUS91343.1 - 0.011 15.6 2.7 0.011 15.6 2.7 5.9 3 2 0 4 4 4 0 PHD-finger PRKCSH_1 PF13015.6 RUS91344.1 - 7.6e-14 51.7 0.1 4.2e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RUS91344.1 - 5.7e-07 30.5 0.6 5.7e-07 30.5 0.6 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4201 PF13870.6 RUS91344.1 - 0.018 14.8 0.8 0.028 14.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) PI3K_P85_iSH2 PF16454.5 RUS91344.1 - 0.033 13.8 4.0 0.053 13.1 4.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Myb_DNA-bind_4 PF13837.6 RUS91344.1 - 0.06 13.7 0.4 0.12 12.8 0.4 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CLZ PF16526.5 RUS91344.1 - 0.11 12.9 0.2 0.11 12.9 0.2 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels T3SchapCesA PF11439.8 RUS91344.1 - 0.13 12.4 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA FapA PF03961.13 RUS91344.1 - 0.19 10.3 0.8 0.24 10.0 0.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TLE_N PF03920.15 RUS91344.1 - 0.2 11.7 3.0 0.15 12.1 1.1 1.8 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DMAP_binding PF06464.11 RUS91344.1 - 0.2 12.4 2.2 1.3 9.8 0.1 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain TSC22 PF01166.18 RUS91344.1 - 0.32 11.4 3.0 0.35 11.2 0.6 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-primase PF09329.11 RUS91344.1 - 0.93 9.3 4.0 28 4.6 0.4 3.1 2 1 0 2 2 2 0 Primase zinc finger RhoGAP PF00620.27 RUS91345.1 - 7.8e-42 142.7 0.0 2.8e-41 140.8 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain PDZ PF00595.24 RUS91345.1 - 1.3e-13 51.1 0.3 2.9e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 RUS91345.1 - 4.7e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 RUS91345.1 - 0.00033 20.4 0.1 0.0009 19.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS91345.1 - 0.1 12.9 0.2 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 PDZ domain Reeler PF02014.16 RUS91346.1 - 2.6e-16 60.5 0.0 4.7e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Reeler domain DOMON PF03351.17 RUS91346.1 - 7.5e-10 39.1 1.6 9.3e-10 38.8 0.1 2.0 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 RUS91346.1 - 7.5e-08 32.6 5.4 7.5e-08 32.6 5.4 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 YfhO PF09586.10 RUS91346.1 - 0.1 10.8 4.7 0.2 9.9 4.7 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ni_hydr_CYTB PF01292.20 RUS91346.1 - 1.9 8.0 14.1 1.4 8.5 1.3 2.7 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 JAB PF01398.21 RUS91347.1 - 1.3e-33 115.4 0.1 2.6e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 RUS91347.1 - 1.8e-21 76.8 1.4 6.1e-21 75.1 0.3 2.1 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 RUS91347.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RUS91347.1 - 0.001 19.2 0.2 0.0024 18.0 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) SelP_N PF04592.14 RUS91348.1 - 1.8e-30 106.1 0.0 2.2e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region MORN PF02493.20 RUS91349.1 - 4.9e-31 104.8 45.2 1.4e-05 24.7 0.6 7.2 7 0 0 7 7 7 6 MORN repeat DUF3048_C PF17479.2 RUS91349.1 - 0.17 12.3 15.3 1.9 8.9 0.1 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain PATR PF12951.7 RUS91349.1 - 2.6 8.3 0.0 2.6 8.3 0.0 3.6 5 1 0 5 5 5 0 Passenger-associated-transport-repeat ADAM_spacer1 PF05986.14 RUS91351.1 - 6.7e-34 116.3 0.0 1.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 RUS91351.1 - 4.7e-31 107.9 0.5 1.5e-30 106.3 0.5 1.9 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 RUS91351.1 - 2.5e-22 79.8 0.1 5.8e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 RUS91351.1 - 5.3e-16 58.9 7.7 5.3e-16 58.9 7.7 6.3 5 1 1 6 6 6 2 ADAM cysteine-rich domain TSP_1 PF00090.19 RUS91351.1 - 6.7e-13 48.6 96.1 6.4e-06 26.3 12.1 8.1 7 1 0 7 7 7 5 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 RUS91351.1 - 1e-12 48.6 1.5 2.6e-12 47.3 1.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 PLAC PF08686.11 RUS91351.1 - 2.6e-09 37.7 8.6 2.1e-08 34.8 8.6 2.8 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Reprolysin_3 PF13582.6 RUS91351.1 - 2.6e-09 37.6 0.2 5.8e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS91351.1 - 3.2e-09 37.0 0.1 7.3e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS91351.1 - 0.0001 22.0 2.4 0.00024 20.8 2.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like FhuF_C PF11575.8 RUS91352.1 - 7.7 6.6 9.6 16 5.6 0.2 3.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain RNase_H PF00075.24 RUS91353.1 - 5.8e-39 133.5 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 RUS91353.1 - 3.7e-19 68.7 0.3 3.7e-19 68.7 0.3 2.2 3 0 0 3 3 3 1 Caulimovirus viroplasmin RVT_3 PF13456.6 RUS91353.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like DDE_Tnp_IS1595 PF12762.7 RUS91354.1 - 0.00039 20.5 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Gal-bind_lectin PF00337.22 RUS91355.1 - 3.4e-12 46.0 0.0 6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin PhyH PF05721.13 RUS91356.1 - 1.3e-26 94.2 0.0 1.5e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Swi3 PF07962.12 RUS91358.1 - 9.5e-07 28.7 4.8 8.2 6.5 0.0 7.0 6 2 2 8 8 8 1 Replication Fork Protection Component Swi3 WcbI PF18588.1 RUS91358.1 - 3.9e-05 23.4 1.4 0.84 9.2 0.0 4.0 3 1 1 4 4 4 3 Polysaccharide biosynthesis enzyme WcbI DUF1286 PF06939.11 RUS91358.1 - 0.0002 21.6 22.4 12 6.2 0.6 7.8 1 1 6 8 8 8 4 Protein of unknown function (DUF1286) Thymidylat_synt PF00303.19 RUS91358.1 - 3 6.9 7.9 19 4.3 1.6 4.5 2 1 1 4 4 4 0 Thymidylate synthase cNMP_binding PF00027.29 RUS91359.1 - 9.9e-11 41.6 0.0 0.00072 19.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF1754 PF08555.10 RUS91361.1 - 1.6e-05 25.6 22.9 6.7e-05 23.6 13.4 2.4 2 1 1 3 3 3 2 Eukaryotic family of unknown function (DUF1754) DUF1442 PF07279.11 RUS91361.1 - 0.039 13.3 0.2 0.046 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) CDK5_activator PF03261.15 RUS91361.1 - 0.095 12.2 2.9 0.11 12.1 2.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SPATA6 PF14909.6 RUS91362.1 - 8e-51 171.8 0.0 1.3e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 ATG11 PF10377.9 RUS91363.1 - 6.8e-17 61.7 0.0 6.8e-17 61.7 0.0 4.1 4 1 1 5 5 5 1 Autophagy-related protein 11 TBK1_ULD PF18396.1 RUS91363.1 - 5e-06 26.4 0.1 0.00025 20.9 0.0 3.3 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 RUS91363.1 - 0.057 13.2 5.9 0.087 12.6 0.0 4.2 4 0 0 4 4 4 0 Ubiquitin family SlyX PF04102.12 RUS91363.1 - 0.072 13.7 0.1 0.072 13.7 0.1 11.7 12 1 1 13 13 13 0 SlyX SYCP2_SLD PF18584.1 RUS91364.1 - 3.8e-17 62.5 0.1 1.8e-16 60.3 0.1 2.3 1 0 0 1 1 1 1 Synaptonemal complex 2 Spt16M-like domain GCM PF03615.15 RUS91365.1 - 1.7e-69 232.1 1.8 5.7e-69 230.4 1.8 2.0 1 0 0 1 1 1 1 GCM motif protein FNIP_M PF14637.6 RUS91366.1 - 1.3e-81 274.0 0.4 2.4e-81 273.0 0.4 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 RUS91366.1 - 7.8e-57 192.0 3.4 1.2e-56 191.4 0.1 2.3 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 RUS91367.1 - 2.9e-08 34.8 0.2 2.9e-08 34.8 0.2 2.0 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus L_HMGIC_fpl PF10242.9 RUS91368.1 - 0.0037 17.5 0.6 0.0037 17.5 0.6 2.0 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 RUS91368.1 - 0.01 15.6 13.2 1.9 8.2 12.7 2.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Smim3 PF17307.2 RUS91368.1 - 0.078 12.5 1.5 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 Small integral membrane protein 3 PMP22_Claudin PF00822.20 RUS91368.1 - 0.38 10.6 9.8 1.4 8.7 9.6 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SR-25 PF10500.9 RUS91369.1 - 0.031 13.9 6.9 0.038 13.6 6.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aa_trans PF01490.18 RUS91370.1 - 1.9e-46 158.6 7.8 5.1e-23 81.4 0.1 3.0 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Cytochrom_B561 PF03188.16 RUS91370.1 - 0.00073 19.7 0.4 0.00073 19.7 0.4 2.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 FAM176 PF14851.6 RUS91370.1 - 0.0016 18.1 0.0 0.012 15.3 0.0 2.3 3 0 0 3 3 3 1 FAM176 family zf-CCCH PF00642.24 RUS91371.1 - 3.7e-17 61.8 32.8 2.5e-06 27.2 0.4 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RUS91371.1 - 3e-13 49.3 52.2 1e-06 28.5 2.0 7.0 6 1 0 6 6 6 4 Zinc finger domain Torus PF16131.5 RUS91371.1 - 8.3e-13 49.0 27.1 0.00024 21.8 0.3 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 RUS91371.1 - 4.2e-09 36.6 29.3 1.3e-08 35.0 10.9 2.9 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCHC PF00098.23 RUS91371.1 - 3.8e-08 33.0 15.8 4.8e-07 29.6 3.1 4.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_4 PF18044.1 RUS91371.1 - 2.2e-05 24.1 0.4 2.2e-05 24.1 0.4 5.1 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RUS91371.1 - 4.4e-05 23.8 48.7 0.078 13.5 0.5 6.3 6 1 0 6 6 6 5 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 RUS91371.1 - 0.00021 21.2 6.3 0.11 12.5 0.8 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 RUS91371.1 - 0.0032 17.3 15.1 0.043 13.7 1.6 4.2 3 0 0 3 3 3 2 Zinc knuckle zf-C3H1 PF10650.9 RUS91371.1 - 0.0065 16.2 1.8 0.023 14.4 1.0 5.4 6 0 0 6 6 6 3 Putative zinc-finger domain CSD2 PF17876.1 RUS91371.1 - 0.041 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Cold shock domain zf-CCHC_4 PF14392.6 RUS91371.1 - 0.42 10.4 7.7 0.76 9.6 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle Arrestin_N PF00339.29 RUS91372.1 - 2.7e-09 37.2 0.2 7.3e-08 32.6 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RUS91372.1 - 2.2e-05 24.9 0.0 0.37 11.3 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain IL13 PF03487.13 RUS91372.1 - 0.085 12.6 0.1 0.3 10.9 0.0 1.8 1 1 1 2 2 2 0 Interleukin-13 Rgp1 PF08737.10 RUS91372.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Rgp1 PP28 PF10252.9 RUS91374.1 - 8.4e-27 93.4 16.1 8.4e-27 93.4 16.1 2.3 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 ATP-synt_E PF05680.12 RUS91374.1 - 3.4 8.1 28.6 0.25 11.7 7.7 2.6 2 1 0 2 2 2 0 ATP synthase E chain MARVEL PF01284.23 RUS91375.1 - 1.4 8.9 11.7 0.95 9.5 7.6 2.0 1 1 0 2 2 2 0 Membrane-associating domain ABC_membrane PF00664.23 RUS91376.1 - 5.6e-81 272.2 43.0 7.5e-46 157.0 12.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS91376.1 - 3.8e-53 179.7 0.2 3.3e-30 105.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS91376.1 - 4.9e-10 39.2 2.0 0.0082 15.6 0.1 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS91376.1 - 3.3e-07 30.4 0.3 0.022 14.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RUS91376.1 - 4.2e-06 27.2 0.5 0.16 12.4 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RUS91376.1 - 1.3e-05 24.8 1.2 0.0098 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RUS91376.1 - 1.7e-05 24.8 2.2 0.009 15.9 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS91376.1 - 6.9e-05 23.1 0.1 0.52 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RUS91376.1 - 0.00014 21.8 0.5 0.14 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RUS91376.1 - 0.00039 21.0 1.8 0.27 11.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain TrwB_AAD_bind PF10412.9 RUS91376.1 - 0.00094 18.2 0.2 0.28 10.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 RUS91376.1 - 0.0014 18.2 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 RUS91376.1 - 0.0063 16.1 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RUS91376.1 - 0.0081 15.9 0.9 0.78 9.4 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 RUS91376.1 - 0.011 15.1 1.2 3.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 RUS91376.1 - 0.018 15.1 2.5 0.54 10.3 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_PrkA PF08298.11 RUS91376.1 - 0.019 13.9 0.0 0.34 9.8 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain DUF815 PF05673.13 RUS91376.1 - 0.022 14.0 0.2 6 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 RUS91376.1 - 0.027 13.3 0.9 2.7 6.7 0.0 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 RUS91376.1 - 0.036 14.5 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 RUS91376.1 - 0.047 13.3 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 RUS91376.1 - 0.047 13.3 0.7 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 RUS91376.1 - 0.091 11.7 0.3 8 5.3 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain T2SSE PF00437.20 RUS91376.1 - 0.1 11.6 0.1 9.4 5.2 0.0 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 RUS91376.1 - 0.11 12.7 0.1 31 4.8 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RUS91376.1 - 0.13 12.3 0.3 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 RUS91376.1 - 0.13 11.4 1.4 6.3 5.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain PHO4 PF01384.20 RUS91376.1 - 0.14 11.2 5.0 0.14 11.2 0.3 2.5 2 0 0 2 2 2 0 Phosphate transporter family Dynamin_N PF00350.23 RUS91376.1 - 0.15 12.1 1.4 3.5 7.6 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_11 PF13086.6 RUS91376.1 - 0.61 9.8 3.5 5.7 6.6 1.7 2.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RUS91376.1 - 0.67 9.6 8.5 3.6 7.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF5379 PF17350.2 RUS91376.1 - 4.4 7.6 8.0 1.9 8.8 0.1 3.6 3 0 0 3 3 2 0 Family of unknown function (DUF5379) Sushi PF00084.20 RUS91377.1 - 4.8e-16 59.1 19.6 3.4e-08 33.9 0.1 4.2 5 0 0 5 5 5 3 Sushi repeat (SCR repeat) EGF_CA PF07645.15 RUS91377.1 - 1.3e-13 50.9 31.3 9.3e-08 32.2 5.4 3.8 4 0 0 4 4 4 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 RUS91377.1 - 7.3e-08 32.6 28.2 7e-07 29.4 3.9 4.4 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS91377.1 - 1.6e-06 27.9 24.9 7e-05 22.7 1.8 5.6 5 1 0 5 5 5 2 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS91377.1 - 2.6e-06 27.5 26.8 0.0038 17.4 4.9 4.3 4 0 0 4 4 4 2 EGF domain EGF PF00008.27 RUS91377.1 - 4.4e-05 23.7 27.0 0.00013 22.1 3.5 4.4 5 1 0 5 5 5 2 EGF-like domain hEGF PF12661.7 RUS91377.1 - 6.4e-05 23.4 8.3 0.0036 17.9 1.5 5.4 6 1 0 6 6 6 2 Human growth factor-like EGF EGF PF00008.27 RUS91378.1 - 1.7e-19 69.8 65.0 2.5e-09 37.3 8.9 11.7 12 1 0 12 12 12 7 EGF-like domain EGF_CA PF07645.15 RUS91378.1 - 3.8e-08 33.4 33.0 2.2e-06 27.7 12.6 10.3 6 3 5 11 11 11 2 Calcium-binding EGF domain hEGF PF12661.7 RUS91378.1 - 8.7e-06 26.2 28.4 0.00061 20.3 5.3 11.9 11 2 0 11 11 11 5 Human growth factor-like EGF EGF_2 PF07974.13 RUS91378.1 - 9e-05 22.8 50.8 0.0031 17.9 12.3 10.4 8 3 1 9 9 9 4 EGF-like domain FXa_inhibition PF14670.6 RUS91378.1 - 0.00048 20.4 6.0 0.00048 20.4 6.0 9.5 6 2 3 9 9 9 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 RUS91378.1 - 0.016 15.1 4.3 0.016 15.1 4.3 7.9 8 0 0 8 8 8 0 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS91378.1 - 0.02 15.1 3.1 0.02 15.1 3.1 10.6 7 3 2 9 9 9 0 EGF domain rve PF00665.26 RUS91379.1 - 1.9e-09 37.7 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HYR PF02494.16 RUS91379.1 - 0.0051 17.1 0.2 0.012 15.9 0.2 1.7 1 0 0 1 1 1 1 HYR domain Laminin_G_3 PF13385.6 RUS91379.1 - 0.02 15.0 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 RUS91380.1 - 2.7e-25 87.8 34.6 3e-13 49.3 3.4 4.3 4 0 0 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 RUS91380.1 - 0.033 14.2 39.0 0.072 13.1 2.6 5.6 1 1 3 5 5 5 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 RUS91380.1 - 0.39 11.2 35.5 0.45 11.0 2.2 6.0 4 3 2 6 6 6 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 RUS91381.1 - 1.1e-28 98.7 41.0 1e-09 38.0 1.6 5.1 4 1 1 5 5 5 5 Putative ephrin-receptor like WD40 PF00400.32 RUS91382.1 - 5.1e-05 24.0 0.4 0.43 11.5 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.6 RUS91382.1 - 0.00078 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 RUS91382.1 - 0.13 12.6 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain G6PD_N PF00479.22 RUS91384.1 - 1.3e-13 51.9 0.0 1.9e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 RUS91385.1 - 4e-51 173.9 0.1 1.6e-50 172.0 0.1 1.7 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RUS91385.1 - 0.045 14.4 0.7 0.098 13.3 0.1 1.8 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain I-set PF07679.16 RUS91386.1 - 1.5e-28 98.7 0.0 4.9e-14 52.2 0.0 2.0 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS91386.1 - 6.3e-27 94.0 0.1 5.2e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 RUS91386.1 - 2.6e-20 72.5 0.0 8.2e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 RUS91386.1 - 5.3e-16 58.6 0.0 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 RUS91386.1 - 9.4e-08 32.0 0.1 0.0075 16.3 0.0 2.6 2 2 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 RUS91386.1 - 6.7e-07 29.5 1.1 0.025 14.7 0.1 3.2 2 2 0 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 RUS91386.1 - 2e-06 28.1 0.0 0.0033 17.8 0.0 2.8 2 1 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 RUS91386.1 - 0.022 14.8 0.1 2.4 8.2 0.0 2.7 2 1 0 2 2 2 0 C17orf99 Ig domain C1-set PF07654.15 RUS91386.1 - 0.11 12.8 0.1 3.4 8.1 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin C1-set domain Laminin_I PF06008.14 RUS91388.1 - 0.37 10.4 3.7 0.18 11.5 0.3 1.8 1 1 1 2 2 2 0 Laminin Domain I Laminin_G_2 PF02210.24 RUS91390.1 - 7.2e-24 84.8 1.0 2.7e-14 53.8 0.4 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 RUS91390.1 - 5.5e-16 59.0 0.6 1.2e-10 41.7 0.1 3.2 3 1 0 3 3 3 2 Laminin G domain Laminin_G_3 PF13385.6 RUS91390.1 - 0.012 15.8 0.3 0.35 11.0 0.0 3.1 4 0 0 4 4 4 0 Concanavalin A-like lectin/glucanases superfamily Vps62 PF06101.11 RUS91390.1 - 0.018 13.4 0.0 0.025 12.9 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 ADH_zinc_N_2 PF13602.6 RUS91391.1 - 0.038 15.0 0.0 0.058 14.5 0.0 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase COX8 PF02285.15 RUS91391.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Rz1 PF06085.11 RUS91391.1 - 0.14 11.9 0.3 2.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Lipoprotein Rz1 precursor ADH_N PF08240.12 RUS91392.1 - 0.00036 20.4 0.1 0.00057 19.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RUS91392.1 - 0.03 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SH3_9 PF14604.6 RUS91393.1 - 7.5e-60 198.6 7.3 6e-18 64.4 0.1 5.7 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 RUS91393.1 - 1.3e-54 181.5 10.9 7.1e-15 54.4 0.1 5.6 5 0 0 5 5 5 5 SH3 domain PH_13 PF16652.5 RUS91393.1 - 2.1e-50 170.6 0.1 2.1e-50 170.6 0.1 3.2 3 0 0 3 3 2 1 Pleckstrin homology domain SH3_2 PF07653.17 RUS91393.1 - 1.1e-43 146.6 0.0 3.8e-09 36.1 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.20 RUS91393.1 - 2.4e-40 138.7 0.0 2.4e-40 138.7 0.0 2.3 3 0 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.7 RUS91393.1 - 2.1e-26 91.9 0.0 2.6e-12 46.6 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 RUS91393.1 - 2.9e-24 85.3 0.0 1.4e-23 83.2 0.0 2.2 2 0 0 2 2 1 1 C2 domain EF-hand_1 PF00036.32 RUS91393.1 - 8.3e-10 37.5 0.3 0.00073 18.9 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RUS91393.1 - 1.5e-06 27.6 0.2 0.26 11.3 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RUS91393.1 - 4.6e-06 27.0 0.0 0.0058 17.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RUS91393.1 - 0.00056 19.7 0.7 0.055 13.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS91393.1 - 0.025 14.1 0.2 11 5.7 0.1 2.8 2 0 0 2 2 2 0 EF hand DDHD PF02862.17 RUS91393.1 - 0.58 10.3 14.5 0.33 11.1 5.1 2.6 2 0 0 2 2 2 0 DDHD domain VCBS PF13517.6 RUS91393.1 - 0.79 10.4 2.2 21 5.8 0.1 3.1 3 0 0 3 3 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3510 PF12022.8 RUS91395.1 - 1.2e-36 125.9 0.1 1.6e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) SAYSvFN PF10260.9 RUS91396.1 - 3.1e-25 87.9 0.1 6e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Ycf66_N PF07444.11 RUS91396.1 - 0.13 12.4 1.4 0.21 11.7 1.4 1.3 1 0 0 1 1 1 0 Ycf66 protein N-terminus LRR_6 PF13516.6 RUS91397.1 - 7.5e-21 72.4 7.2 0.0019 18.1 0.0 8.3 8 0 0 8 8 8 5 Leucine Rich repeat EF-hand_1 PF00036.32 RUS91397.1 - 7.1e-10 37.7 1.7 0.00021 20.6 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RUS91397.1 - 6e-09 35.1 0.8 0.0019 18.0 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS91397.1 - 1.9e-08 34.6 0.8 4.3e-08 33.5 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS91397.1 - 5e-08 32.7 0.2 1.4e-07 31.3 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RUS91397.1 - 6.7e-06 25.4 1.5 0.0043 16.5 0.6 2.7 2 0 0 2 2 2 2 EF hand LRR_1 PF00560.33 RUS91397.1 - 0.0058 17.0 0.2 21 6.1 0.0 5.2 6 0 0 6 6 6 1 Leucine Rich Repeat Methyltransf_25 PF13649.6 RUS91398.1 - 5.8e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS91398.1 - 1.5e-06 28.7 0.0 2.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS91398.1 - 6.5e-05 22.8 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS91398.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RUS91398.1 - 0.0034 18.1 0.0 0.0065 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PknG_rubred PF16919.5 RUS91398.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Methyltransf_32 PF13679.6 RUS91398.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 RUS91398.1 - 0.044 13.3 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Acyl_transf_3 PF01757.22 RUS91399.1 - 1.8e-20 73.3 32.8 3e-20 72.5 32.8 1.3 1 0 0 1 1 1 1 Acyltransferase family Globin PF00042.22 RUS91400.1 - 3.1e-13 50.2 0.0 4.7e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Globin Sfi1_C PF10638.9 RUS91400.1 - 0.03 15.1 0.0 0.053 14.3 0.0 1.3 1 0 0 1 1 1 0 Spindle body associated protein C-terminus BAALC_N PF06989.12 RUS91400.1 - 0.049 14.0 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 BAALC N-terminus Vault PF01505.18 RUS91401.1 - 1e-58 195.2 1.2 7.3e-17 61.3 0.1 5.2 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 RUS91401.1 - 4.9e-52 174.9 0.1 9.3e-52 174.1 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 RUS91401.1 - 9.2e-36 122.0 0.4 1.1e-18 67.3 0.1 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 RUS91401.1 - 2.5e-31 107.5 0.2 2.3e-29 101.2 0.0 3.1 3 1 0 3 3 3 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 RUS91401.1 - 3.1e-30 104.0 0.2 1.4e-29 102.0 0.2 2.2 1 0 0 1 1 1 1 Major Vault Protein repeat domain MRP-S33 PF08293.11 RUS91402.1 - 0.0057 16.9 0.4 1 9.6 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial ribosomal subunit S27 hnRNP_Q_AcD PF18360.1 RUS91402.1 - 0.037 14.0 0.6 4.9 7.2 0.0 4.0 3 2 1 4 4 4 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Lipin_N PF04571.14 RUS91402.1 - 0.2 11.6 2.0 30 4.7 0.0 3.6 2 2 2 4 4 4 0 lipin, N-terminal conserved region PCC_BT PF18140.1 RUS91403.1 - 0.00054 20.3 1.5 0.3 11.4 0.2 3.4 1 1 3 5 5 5 1 Propionyl-coenzyme A carboxylase BT domain Big_3_4 PF13754.6 RUS91403.1 - 0.00065 19.4 4.0 24 4.7 0.1 5.1 2 2 3 5 5 5 0 Domain of unknown function CNOT11 PF10155.9 RUS91403.1 - 0.0052 16.9 3.9 9.3 6.4 0.1 4.5 3 2 2 5 5 5 1 CCR4-NOT transcription complex subunit 11 DUF4825 PF16107.5 RUS91403.1 - 0.032 14.4 9.5 5.3 7.2 0.6 4.7 2 1 4 6 6 6 0 Domain of unknown function (DUF4825) BPL_C PF02237.17 RUS91403.1 - 0.032 14.1 3.4 1e+02 2.9 0.0 5.8 7 2 0 7 7 7 0 Biotin protein ligase C terminal domain PPR_long PF17177.4 RUS91403.1 - 0.052 12.9 9.1 0.042 13.2 1.6 3.2 2 1 2 4 4 4 0 Pentacotripeptide-repeat region of PRORP Binary_toxB PF03495.14 RUS91403.1 - 0.087 13.0 13.0 1.9 8.7 0.2 5.1 1 1 2 5 5 5 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Thiol_cytolys_C PF17440.2 RUS91403.1 - 0.11 12.7 8.2 34 4.7 0.1 5.5 1 1 3 7 7 7 0 Thiol-activated cytolysin beta sandwich domain DAPDH_C PF16654.5 RUS91403.1 - 0.17 11.7 6.8 3.9 7.3 0.1 4.2 2 2 2 5 5 5 0 Diaminopimelic acid dehydrogenase C-terminal domain Asp_Arg_Hydrox PF05118.15 RUS91403.1 - 0.31 10.8 8.8 6.6 6.5 0.2 5.0 1 1 4 5 5 5 0 Aspartyl/Asparaginyl beta-hydroxylase DUF5514 PF17633.2 RUS91403.1 - 0.34 11.1 3.3 19 5.5 0.0 3.7 2 1 2 4 4 4 0 Family of unknown function (DUF5514) Glyco_hydro_2 PF00703.21 RUS91403.1 - 0.38 11.4 6.1 94 3.7 0.0 5.2 3 2 2 5 5 5 0 Glycosyl hydrolases family 2 PKD_channel PF08016.12 RUS91405.1 - 5.7e-43 147.2 9.7 5.7e-43 147.2 9.7 2.1 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 RUS91405.1 - 0.083 13.5 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 PLAT/LH2 domain Cnd3 PF12719.7 RUS91407.1 - 0.03 13.5 2.7 0.047 12.9 2.0 1.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain BLYB PF05289.11 RUS91407.1 - 0.03 14.5 0.2 0.099 12.9 0.2 1.9 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein Dymeclin PF09742.9 RUS91407.1 - 0.044 12.2 1.5 0.05 12.0 1.5 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DRIM PF07539.12 RUS91407.1 - 0.76 8.0 9.1 8.3 4.6 9.1 2.8 1 1 0 1 1 1 0 Down-regulated in metastasis SDA1 PF05285.12 RUS91408.1 - 0.00031 20.3 39.8 0.00035 20.1 39.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 RUS91408.1 - 0.066 11.4 44.6 0.08 11.1 44.6 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 RUS91408.1 - 0.095 12.1 33.8 0.12 11.8 33.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 RUS91408.1 - 3.3 7.0 40.9 3.8 6.7 40.9 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 RUS91408.1 - 4.7 5.9 15.9 5.5 5.7 15.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FYVE_2 PF02318.16 RUS91409.1 - 1.7e-08 34.7 6.6 1.7e-08 34.7 6.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger p450 PF00067.22 RUS91410.1 - 3.1e-108 362.5 0.0 3.5e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAN_1 PF00024.26 RUS91411.1 - 0.0001 22.2 1.0 0.00016 21.5 1.0 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 RUS91411.1 - 0.00037 20.3 0.3 0.00062 19.5 0.3 1.3 1 0 0 1 1 1 1 PAN-like domain Ig_3 PF13927.6 RUS91412.1 - 1.4e-79 262.7 3.1 4.5e-14 52.8 0.0 10.5 10 0 0 10 10 10 7 Immunoglobulin domain I-set PF07679.16 RUS91412.1 - 9.4e-75 246.8 0.0 1.4e-15 57.1 0.0 7.5 8 0 0 8 8 8 5 Immunoglobulin I-set domain Ig_2 PF13895.6 RUS91412.1 - 6e-58 193.1 2.5 6.5e-11 42.4 0.0 9.3 10 0 0 10 10 9 5 Immunoglobulin domain ig PF00047.25 RUS91412.1 - 4.1e-45 151.9 0.0 9.3e-08 32.1 0.0 8.8 10 0 0 10 10 10 6 Immunoglobulin domain V-set PF07686.17 RUS91412.1 - 2.3e-23 82.5 8.0 0.0044 17.2 0.0 10.7 8 5 3 11 11 11 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS91412.1 - 1.4e-19 69.9 3.9 0.016 15.2 0.0 7.1 7 0 0 7 7 6 5 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 RUS91412.1 - 8.2e-16 58.0 0.1 0.0065 16.7 0.0 7.3 7 0 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 RUS91412.1 - 4.9e-15 55.7 0.0 0.047 14.1 0.0 7.3 8 0 0 8 8 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 RUS91412.1 - 1.1e-09 37.7 0.0 0.26 10.9 0.0 5.7 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 RUS91412.1 - 1.4e-06 28.3 0.4 6.3 6.9 0.0 5.5 6 0 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 RUS91412.1 - 1.5e-05 24.9 0.0 18 5.5 0.0 6.2 6 0 0 6 6 6 0 C17orf99 Ig domain Herpes_gE PF02480.16 RUS91412.1 - 0.00085 18.2 0.0 0.35 9.6 0.0 4.1 5 0 0 5 5 5 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR1 PF02440.15 RUS91412.1 - 0.0045 16.7 0.0 31 4.4 0.0 5.0 6 0 0 6 6 5 0 Adenovirus E3 region protein CR1 C2-set PF05790.15 RUS91412.1 - 0.019 15.1 0.0 48 4.2 0.0 4.7 5 0 0 5 5 5 0 Immunoglobulin C2-set domain C1-set PF07654.15 RUS91412.1 - 0.065 13.6 3.8 4 7.9 0.0 5.1 6 1 0 6 6 6 0 Immunoglobulin C1-set domain BioY PF02632.14 RUS91415.1 - 0.0038 17.3 12.5 0.12 12.5 12.2 2.0 1 1 0 1 1 1 1 BioY family SecE PF00584.20 RUS91415.1 - 1.9 8.5 35.0 1 9.3 3.6 4.9 1 1 3 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex DUF2798 PF11391.8 RUS91415.1 - 5.7 7.1 33.6 74 3.5 12.2 4.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2798) DUF5455 PF17537.2 RUS91415.1 - 6 7.3 17.6 44 4.5 0.7 4.2 1 1 1 2 2 2 0 Family of unknown function (DUF5455) TSP_1 PF00090.19 RUS91416.1 - 5.1e-09 36.2 9.4 1e-08 35.3 9.4 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain Laminin_G_2 PF02210.24 RUS91416.1 - 0.039 14.5 0.2 0.13 12.8 0.1 1.7 1 1 1 2 2 2 0 Laminin G domain Laminin_G_3 PF13385.6 RUS91416.1 - 0.052 13.7 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily GlyL_C PF12524.8 RUS91416.1 - 1 9.5 5.6 13 6.1 0.3 2.9 3 1 0 3 3 3 0 dsDNA virus glycoprotein L C terminal NtA PF03146.15 RUS91417.1 - 4.2e-12 45.9 0.0 0.00029 20.6 0.0 3.2 3 0 0 3 3 3 3 Agrin NtA domain FixS PF03597.15 RUS91417.1 - 1.7e-06 27.6 1.1 2.6 7.8 0.0 3.9 3 0 0 3 3 3 3 Cytochrome oxidase maturation protein cbb3-type TFIIIC_sub6 PF10419.9 RUS91417.1 - 0.0012 18.7 0.0 18 5.3 0.0 3.3 3 0 0 3 3 3 0 TFIIIC subunit triple barrel domain DUF2401 PF10287.9 RUS91417.1 - 0.0025 17.4 0.3 8 6.0 0.0 3.1 3 0 0 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) Glycoprot_B_PH1 PF17416.2 RUS91417.1 - 0.0035 17.0 0.0 15 5.2 0.0 3.1 3 0 0 3 3 3 0 Herpesvirus Glycoprotein B Cwf_Cwc_15 PF04889.12 RUS91417.1 - 0.018 14.8 19.2 0.026 14.3 19.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RUS91417.1 - 0.16 10.2 11.5 0.2 9.8 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 RUS91417.1 - 0.36 11.1 17.9 0.57 10.4 17.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 RUS91417.1 - 0.48 10.0 10.3 0.67 9.5 10.3 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 RUS91417.1 - 0.52 9.6 24.8 0.8 9.0 24.8 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RUS91417.1 - 0.69 9.8 9.7 1.1 9.1 9.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 RUS91417.1 - 1.3 9.1 11.4 2.2 8.3 11.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 RUS91417.1 - 1.9 7.7 9.3 2.6 7.3 9.3 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RUS91417.1 - 2.2 7.6 13.3 3.1 7.1 13.3 1.1 1 0 0 1 1 1 0 SDA1 HEAT PF02985.22 RUS91420.1 - 4e-09 36.0 0.0 0.0034 17.5 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.6 RUS91420.1 - 2.5e-05 24.6 0.1 0.016 15.7 0.0 3.5 3 1 1 4 4 4 1 HEAT-like repeat MMS19_C PF12460.8 RUS91420.1 - 4.5e-05 22.8 0.1 0.12 11.4 0.0 2.7 1 1 0 2 2 2 2 RNAPII transcription regulator C-terminal ParcG PF10274.9 RUS91420.1 - 0.00025 21.2 0.6 0.62 10.2 0.0 2.7 2 1 1 3 3 3 3 Parkin co-regulated protein Xpo1 PF08389.12 RUS91420.1 - 0.00044 20.3 0.1 0.057 13.5 0.1 2.2 1 1 1 2 2 2 1 Exportin 1-like protein IFRD PF05004.13 RUS91420.1 - 0.0016 17.6 0.0 0.0048 16.0 0.0 1.7 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Sec7_N PF12783.7 RUS91420.1 - 0.0019 18.1 0.3 5.1 7.0 0.0 3.2 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Tti2 PF10521.9 RUS91420.1 - 0.0027 17.3 0.1 3.1 7.2 0.0 2.5 1 1 0 2 2 2 2 Tti2 family Adaptin_N PF01602.20 RUS91420.1 - 0.0044 15.7 0.5 0.97 7.9 0.0 2.6 1 1 0 2 2 2 2 Adaptin N terminal region RBD-FIP PF09457.10 RUS91420.1 - 0.028 14.3 2.0 0.64 10.0 0.1 3.3 4 1 0 4 4 4 0 FIP domain SEN1_N PF12726.7 RUS91420.1 - 0.032 12.5 0.0 0.057 11.6 0.0 1.3 1 0 0 1 1 1 0 SEN1 N terminal CLASP_N PF12348.8 RUS91420.1 - 0.034 13.7 0.3 1.8 8.0 0.1 2.4 2 1 0 2 2 2 0 CLASP N terminal Dopey_N PF04118.14 RUS91420.1 - 0.037 13.1 0.1 0.91 8.6 0.0 2.1 2 0 0 2 2 2 0 Dopey, N-terminal V-ATPase_H_C PF11698.8 RUS91420.1 - 0.1 12.7 0.2 15 5.7 0.0 2.8 3 0 0 3 3 3 0 V-ATPase subunit H NAR PF16251.5 RUS91421.1 - 0.068 13.9 0.0 0.27 11.9 0.0 1.8 2 0 0 2 2 2 0 Nucleic acid-binding domain (NAR) Pex24p PF06398.11 RUS91422.1 - 3.7e-08 32.7 0.1 4.7e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DNA_pol_phi PF04931.13 RUS91422.1 - 0.009 14.2 0.0 0.011 13.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi 7TM_GPCR_Srw PF10324.9 RUS91423.1 - 2.1e-06 27.3 3.2 2.1e-06 27.2 3.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS91423.1 - 6.3e-05 22.4 3.6 7.6e-05 22.2 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91423.1 - 0.0028 17.1 1.7 0.0035 16.7 1.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SDA1 PF05285.12 RUS91424.1 - 0.013 14.9 99.1 0.097 12.1 48.9 2.0 2 0 0 2 2 2 0 SDA1 7TM_GPCR_Srw PF10324.9 RUS91425.1 - 1.3e-38 133.1 15.7 1.7e-38 132.7 15.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS91425.1 - 1.1e-17 64.2 17.1 5.1e-17 62.1 17.1 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91425.1 - 0.013 14.9 0.1 0.013 14.9 0.1 3.1 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM154 PF15102.6 RUS91425.1 - 0.025 14.5 1.1 0.077 12.9 0.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family DUF3452 PF11934.8 RUS91425.1 - 0.17 11.4 5.8 1.4 8.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) PDEase_I PF00233.19 RUS91426.1 - 6.7e-21 75.1 2.8 1.1e-20 74.4 2.8 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 RUS91426.1 - 1.3e-11 45.3 0.0 2.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 RUS91426.1 - 0.00079 19.8 0.0 0.032 14.6 0.0 2.3 2 0 0 2 2 2 1 GAF domain MIase PF02426.16 RUS91428.1 - 2.6e-07 30.7 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 2 Muconolactone delta-isomerase DUF2827 PF10933.8 RUS91428.1 - 0.052 12.2 0.0 0.09 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) AsnC_trans_reg PF01037.21 RUS91428.1 - 0.075 13.0 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Glycos_transf_2 PF00535.26 RUS91430.1 - 3.9e-10 39.8 0.1 6.2e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HPIH PF13323.6 RUS91430.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Ricin_B_lectin PF00652.22 RUS91431.1 - 1.6e-25 89.8 0.9 3e-25 88.9 0.6 1.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 RUS91431.1 - 7.1e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ALMS_repeat PF18727.1 RUS91432.1 - 6.5e-06 25.9 13.7 3.7 7.5 0.2 6.6 1 1 7 8 8 8 4 Alstrom syndrome repeat Cuticle_4 PF15955.5 RUS91432.1 - 1.1e-05 26.0 14.6 4.5 8.0 0.1 5.0 1 1 7 8 8 8 8 Cuticle protein DuffyBP_N PF12377.8 RUS91432.1 - 5.7e-05 23.4 9.4 74 3.8 0.1 7.5 6 2 2 8 8 8 0 Duffy binding protein N terminal zf_C2H2_6 PF18450.1 RUS91432.1 - 0.016 14.9 1.6 1.1e+02 2.6 0.0 5.4 8 0 0 8 8 8 0 Zinc Finger domain Drf_FH1 PF06346.12 RUS91432.1 - 0.047 13.4 7.7 0.16 11.7 7.7 1.8 1 1 0 1 1 1 0 Formin Homology Region 1 SAB PF04382.13 RUS91432.1 - 0.88 9.7 9.7 97 3.2 0.1 5.4 1 1 7 8 8 8 0 SAB domain DUF3697 PF12478.8 RUS91433.1 - 0.00011 22.2 42.7 0.36 11.0 0.5 8.9 1 1 7 8 8 8 7 Ubiquitin-associated protein 2 CATSPERD PF15020.6 RUS91433.1 - 0.21 9.9 2.6 0.25 9.6 2.6 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Gly_rich_SFCGS PF14272.6 RUS91433.1 - 0.8 9.8 10.6 8.7 6.4 0.9 2.8 1 1 2 3 3 3 0 Glycine-rich SFCGS Spc7 PF08317.11 RUS91434.1 - 0.0016 17.4 6.6 0.0032 16.4 6.6 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF3552 PF12072.8 RUS91434.1 - 0.0066 15.9 6.4 0.065 12.6 6.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) XhlA PF10779.9 RUS91434.1 - 0.017 15.3 35.1 1.8e+04 -15.9 35.1 6.2 1 1 0 1 1 1 0 Haemolysin XhlA CEP63 PF17045.5 RUS91434.1 - 0.067 13.1 10.4 0.042 13.8 8.3 1.6 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF16 PF01519.16 RUS91434.1 - 0.59 10.6 6.4 8.7 6.9 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 RUS91434.1 - 0.75 10.3 5.0 17 5.9 5.0 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF155 PF02582.14 RUS91434.1 - 0.88 9.6 9.2 14 5.7 1.3 2.9 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 HMMR_N PF15905.5 RUS91434.1 - 1.3 8.4 10.2 1.5 8.2 10.2 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4472 PF14739.6 RUS91434.1 - 1.8 9.4 11.6 30 5.4 11.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Prominin PF05478.11 RUS91434.1 - 7.5 4.4 14.0 8.6 4.2 14.0 1.1 1 0 0 1 1 1 0 Prominin Rz1 PF06085.11 RUS91435.1 - 6.2e-28 96.3 61.3 3 7.7 0.0 22.3 1 1 22 23 23 23 22 Lipoprotein Rz1 precursor DUF2685 PF10886.8 RUS91435.1 - 2.9e-12 46.6 14.3 4.1 7.7 0.0 9.6 1 1 15 16 16 16 12 Protein of unknown function (DUF2685) Nodulin-like PF06813.13 RUS91435.1 - 2.3e-06 27.3 14.1 13 5.2 0.1 7.5 1 1 7 10 10 10 6 Nodulin-like DYW_deaminase PF14432.6 RUS91435.1 - 2.9e-05 23.9 21.4 3.4 7.6 0.6 5.8 1 1 5 6 6 6 6 DYW family of nucleic acid deaminases Mg_trans_NIPA PF05653.14 RUS91435.1 - 3.6 6.6 13.8 13 4.8 0.1 5.6 1 1 8 10 10 10 0 Magnesium transporter NIPA WD40 PF00400.32 RUS91436.1 - 5.2e-08 33.4 17.4 50 5.0 0.5 13.3 4 3 1 5 5 5 3 WD domain, G-beta repeat DUF5072 PF16807.5 RUS91437.1 - 0.0045 17.0 1.4 2 8.5 0.0 3.7 1 1 4 5 5 5 2 Domain of unknown function (DUF5072) Pentapeptide_3 PF13576.6 RUS91437.1 - 0.01 16.0 7.7 27 5.0 0.0 5.3 6 0 0 6 6 6 0 Pentapeptide repeats (9 copies) Sad1_UNC PF07738.13 RUS91437.1 - 0.26 11.3 0.5 86 3.1 0.0 3.6 4 0 0 4 4 4 0 Sad1 / UNC-like C-terminal Pecanex_C PF05041.15 RUS91438.1 - 3.8e-09 36.5 0.0 6.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) PT PF04886.12 RUS91438.1 - 3.3 7.3 11.1 6.6 6.4 11.1 1.4 1 0 0 1 1 1 0 PT repeat DUF202 PF02656.15 RUS91439.1 - 4 7.9 7.8 0.38 11.2 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Stig1 PF04885.13 RUS91440.1 - 1.9e-11 44.6 28.7 0.02 15.4 0.8 5.5 1 1 7 8 8 8 8 Stigma-specific protein, Stig1 DUF3699 PF12480.8 RUS91440.1 - 9.1e-10 38.6 0.4 21 5.4 0.0 8.7 1 1 7 8 8 8 2 Protein of unknown function (DUF3699) Stathmin PF00836.19 RUS91440.1 - 4.5e-07 29.9 0.0 43 4.1 0.0 7.6 1 1 7 9 9 9 1 Stathmin family H_lectin PF09458.10 RUS91440.1 - 7.4e-05 22.9 0.4 1.4e+02 2.8 0.0 6.7 1 1 6 7 7 7 0 H-type lectin domain Cyclophil_like2 PF18050.1 RUS91441.1 - 0.0011 18.9 1.5 8.6 6.3 0.0 4.6 1 1 4 5 5 5 2 Cyclophilin-like family DUF3742 PF12553.8 RUS91441.1 - 0.0097 16.0 7.2 26 5.0 0.1 4.8 2 2 3 5 5 5 1 Protein of unknown function (DUF3742) MscS_TM PF12794.7 RUS91441.1 - 0.025 13.4 10.2 0.26 10.1 0.9 2.5 1 1 2 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Colipase-like PF15083.6 RUS91441.1 - 0.22 11.7 3.8 0.86 9.8 0.1 2.8 1 1 1 3 3 3 0 Colipase-like DUF3481 PF11980.8 RUS91441.1 - 2.2 8.1 23.0 6.5 6.5 1.4 5.5 1 1 4 5 5 5 0 C-terminal domain of neuropilin glycoprotein Flp1_like PF16982.5 RUS91442.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Adeno_E3_CR2 PF02439.15 RUS91444.1 - 0.02 14.6 0.5 0.02 14.6 0.5 2.3 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 GAPT PF11770.8 RUS91444.1 - 3.7 7.4 4.0 24 4.8 0.2 2.8 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Endonuclease_5 PF04493.14 RUS91445.1 - 4.4e-63 212.5 0.0 6.4e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 RUS91445.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal SNF2_N PF00176.23 RUS91446.1 - 3.2e-78 262.9 0.3 8.5e-78 261.5 0.3 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 RUS91446.1 - 1.2e-42 144.5 2.8 1.2e-42 144.5 2.8 2.4 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 RUS91446.1 - 5.8e-28 97.9 0.5 5.8e-28 97.9 0.5 3.1 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 RUS91446.1 - 1.3e-19 70.6 0.0 7.1e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RUS91446.1 - 3.4e-09 36.9 0.0 1.8e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DBINO PF13892.6 RUS91446.1 - 7.1e-05 23.2 0.1 7.1e-05 23.2 0.1 4.0 4 0 0 4 4 3 1 DNA-binding domain Myb_DNA-binding PF00249.31 RUS91446.1 - 0.00012 22.2 4.2 0.32 11.2 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DEAD PF00270.29 RUS91446.1 - 0.00016 21.5 0.0 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 RUS91446.1 - 0.00097 18.4 0.0 0.0024 17.1 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF4800 PF16057.5 RUS91446.1 - 0.066 12.5 3.4 0.053 12.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) CDH1_2_SANT_HL1 PF18375.1 RUS91446.1 - 0.44 11.3 4.3 9 7.0 0.1 3.0 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Pkinase PF00069.25 RUS91448.1 - 6.4e-33 114.2 0.0 1.3e-32 113.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91448.1 - 4.3e-24 85.2 0.0 5.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS91448.1 - 0.0016 17.8 0.3 0.0077 15.6 0.3 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RUS91448.1 - 0.024 13.9 0.0 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 RUS91448.1 - 0.036 12.8 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 RUS91449.1 - 2.6e-22 79.4 0.0 3.7e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91449.1 - 2e-14 53.5 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RUS91449.1 - 0.0047 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS91449.1 - 0.053 12.3 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RUS91449.1 - 0.097 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Neur_chan_LBD PF02931.23 RUS91450.1 - 3.7e-06 26.5 0.4 6.9e-06 25.7 0.3 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Flavi_glycoprot PF00869.20 RUS91450.1 - 0.019 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains Mito_carr PF00153.27 RUS91453.1 - 7e-57 189.4 0.9 7.9e-20 70.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 7TM_GPCR_Srw PF10324.9 RUS91456.1 - 1.1e-08 34.7 26.8 7.7e-08 32.0 26.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 RUS91456.1 - 8.2e-06 25.3 16.9 8.2e-06 25.3 16.9 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_I3 PF04661.12 RUS91456.1 - 0.021 13.9 0.2 0.047 12.8 0.2 1.5 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Actin PF00022.19 RUS91457.1 - 6.7e-153 509.1 0.0 2.2e-152 507.4 0.0 1.6 1 1 0 1 1 1 1 Actin DUF1324 PF07038.11 RUS91458.1 - 0.061 13.6 0.2 0.23 11.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) Cu2_monoox_C PF03712.15 RUS91459.1 - 1.3e-24 86.5 1.1 2.2e-24 85.7 0.2 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 RUS91459.1 - 1.2e-07 32.1 0.0 1.2e-07 32.1 0.0 2.3 2 1 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monooxygen PF01082.20 RUS91460.1 - 6.9e-28 97.5 0.2 1.7e-27 96.3 0.2 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 RUS91460.1 - 4.7e-24 84.7 0.9 1.9e-23 82.7 0.0 2.4 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain TSP_1 PF00090.19 RUS91461.1 - 7.2e-20 70.9 22.2 2.6e-14 53.1 11.1 2.0 2 0 0 2 2 2 2 Thrombospondin type 1 domain Notch PF00066.17 RUS91461.1 - 1.4 9.4 0.1 1.4 9.4 0.1 4.1 4 1 0 4 4 4 0 LNR domain zf-C4pol PF14260.6 RUS91461.1 - 2.8 8.5 11.4 3.3 8.2 0.4 2.9 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta G8 PF10162.9 RUS91462.1 - 7.6e-26 90.6 0.0 1.9e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 G8 domain TSP_1 PF00090.19 RUS91462.1 - 1.6e-07 31.4 28.1 2.2e-07 31.0 13.1 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain ILEI PF15711.5 RUS91462.1 - 7.4e-06 26.4 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Interleukin-like EMT inducer Beta_helix PF13229.6 RUS91462.1 - 0.00012 21.9 0.1 0.00012 21.9 0.1 2.8 2 1 0 2 2 2 1 Right handed beta helix region DUF5521 PF17659.1 RUS91463.1 - 1.6e-23 82.6 0.0 1.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5521) Amidinotransf PF02274.17 RUS91465.1 - 2.8e-12 46.4 0.0 8.3e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase EST1_DNA_bind PF10373.9 RUS91468.1 - 3.1e-36 125.3 0.4 3.1e-36 125.3 0.4 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 RUS91468.1 - 7e-22 78.5 0.5 7e-22 78.5 0.5 4.3 4 1 0 4 4 4 1 Telomerase activating protein Est1 TPR_2 PF07719.17 RUS91468.1 - 0.0048 16.9 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS91468.1 - 0.0069 16.7 0.3 0.032 14.6 0.3 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91468.1 - 0.026 14.7 0.0 0.085 13.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 RUS91468.1 - 0.091 12.8 2.4 0.54 10.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RUS91468.1 - 0.19 11.5 1.5 0.43 10.3 1.5 1.6 1 0 0 1 1 1 0 TPR repeat DUF4140 PF13600.6 RUS91468.1 - 4.8 7.7 8.4 0.93 10.0 2.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Treslin_N PF15292.6 RUS91470.1 - 1.4 7.1 4.1 2 6.6 4.1 1.1 1 0 0 1 1 1 0 Treslin N-terminus Acetyltransf_10 PF13673.7 RUS91471.1 - 0.05 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_phi PF04931.13 RUS91472.1 - 0.05 11.7 44.7 0.066 11.3 44.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RUS91472.1 - 0.19 9.9 32.2 0.26 9.5 32.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RUS91472.1 - 0.94 7.7 25.6 1.4 7.1 25.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 RUS91472.1 - 1 9.7 7.9 2.7 8.3 7.9 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 RUS91472.1 - 2.5 6.5 26.0 3.3 6.0 26.0 1.1 1 0 0 1 1 1 0 Mpp10 protein LIM PF00412.22 RUS91475.1 - 5.2e-32 109.9 19.0 6.8e-17 61.4 2.5 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 RUS91475.1 - 1.1e-12 47.6 0.3 1.8e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS91475.1 - 3e-05 23.8 0.1 6.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 RUS91475.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Corazonin PF17308.2 RUS91475.1 - 0.83 10.0 15.5 0.099 13.0 10.9 1.8 2 0 0 2 2 2 0 Pro-corazonin TFIIA PF03153.13 RUS91476.1 - 0.0069 16.4 18.3 0.0087 16.1 18.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 RUS91476.1 - 0.044 13.4 24.6 0.06 12.9 24.6 1.3 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.22 RUS91476.1 - 0.18 11.0 6.6 0.28 10.4 6.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 RUS91476.1 - 0.62 8.2 34.1 0.75 7.9 34.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RUS91476.1 - 0.72 8.8 7.1 0.86 8.5 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 RUS91476.1 - 3.4 6.8 18.0 5.7 6.0 18.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit THOC2_N PF16134.5 RUS91476.1 - 4.5 5.8 7.5 7.5 5.1 7.5 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Menin PF05053.13 RUS91476.1 - 5.2 5.3 9.4 6.1 5.1 9.4 1.2 1 0 0 1 1 1 0 Menin DNA_pol_phi PF04931.13 RUS91476.1 - 5.7 4.9 38.2 7.4 4.5 38.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 RUS91476.1 - 6.1 5.5 13.2 6.5 5.4 13.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 RUS91476.1 - 8.4 4.2 12.7 12 3.7 12.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4483 PF14825.6 RUS91477.1 - 1.1e-37 129.3 0.0 1.6e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Ank_2 PF12796.7 RUS91478.1 - 3.7e-50 168.4 0.1 8.6e-15 55.1 0.3 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91478.1 - 2.4e-42 142.8 6.7 3.3e-13 49.8 1.2 9.1 4 1 6 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 RUS91478.1 - 2.1e-40 135.4 14.9 2.9e-06 27.5 0.2 9.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 RUS91478.1 - 1.3e-36 124.2 8.9 3.3e-08 33.6 0.0 7.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91478.1 - 1.9e-35 116.9 9.5 4.6e-05 23.5 0.1 10.2 10 0 0 10 10 10 7 Ankyrin repeat SOCS_box PF07525.16 RUS91478.1 - 1.5e-06 28.5 0.8 3.2e-06 27.4 0.8 1.6 1 0 0 1 1 1 1 SOCS box VEGFR-2_TMD PF17988.1 RUS91479.1 - 0.34 10.4 1.2 0.88 9.1 1.2 1.7 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DUF4477 PF14780.6 RUS91480.1 - 1.2e-19 70.7 2.2 2e-19 70.0 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) LAGLIDADG_3 PF14528.6 RUS91480.1 - 0.014 15.7 1.7 0.22 11.9 0.1 2.9 2 1 1 3 3 3 0 LAGLIDADG-like domain RNA_pol_Rpc34 PF05158.12 RUS91482.1 - 2e-76 257.6 4.0 4.8e-76 256.3 4.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit EF-hand_14 PF17959.1 RUS91482.1 - 0.024 14.9 0.3 0.092 13.1 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain B-block_TFIIIC PF04182.12 RUS91482.1 - 0.045 13.9 0.8 0.099 12.8 0.8 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF4393 PF14337.6 RUS91482.1 - 0.072 12.9 1.7 0.13 12.1 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) HTH_45 PF14947.6 RUS91482.1 - 0.34 10.9 4.5 1.8 8.6 2.2 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix Glyco_hydro_18 PF00704.28 RUS91483.1 - 1.7e-62 212.0 0.0 2e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 RUS91483.1 - 6.5e-08 32.6 5.0 1.2e-07 31.7 5.0 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Tektin PF03148.14 RUS91484.1 - 2.2e-131 438.2 36.2 2.4e-131 438.0 36.2 1.0 1 0 0 1 1 1 1 Tektin family TraH PF06122.11 RUS91484.1 - 0.01 15.1 1.4 0.013 14.8 1.4 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Vip3A_N PF12495.8 RUS91484.1 - 0.13 12.1 1.8 0.34 10.8 0.9 2.0 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF1664 PF07889.12 RUS91484.1 - 0.55 10.3 16.5 1.6 8.8 5.9 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dad4 PF08650.10 RUS91484.1 - 0.62 10.1 12.0 0.25 11.3 3.4 3.6 3 1 0 3 3 3 0 DASH complex subunit Dad4 Fzo_mitofusin PF04799.13 RUS91484.1 - 0.82 9.2 20.0 0.028 14.0 8.7 3.2 3 1 1 4 4 4 0 fzo-like conserved region JIP_LZII PF16471.5 RUS91484.1 - 1.6 8.9 27.0 3.8 7.8 1.3 5.0 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II DUF948 PF06103.11 RUS91484.1 - 5.8 7.2 8.6 33 4.8 2.6 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NuA4 PF09340.10 RUS91484.1 - 8.9 6.3 7.9 1.8 8.5 0.6 3.1 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Nucleoside_tran PF01733.18 RUS91485.1 - 2.2e-37 129.1 6.2 2.2e-37 129.1 6.2 2.7 1 1 1 2 2 2 1 Nucleoside transporter DUF2172 PF09940.9 RUS91485.1 - 0.19 12.1 0.2 0.43 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Transglut_core PF01841.19 RUS91486.1 - 0.0013 19.1 0.0 0.0044 17.5 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily HC2 PF07382.11 RUS91487.1 - 0.0024 18.0 35.4 0.0024 18.0 35.4 2.0 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 S8_pro-domain PF16470.5 RUS91488.1 - 3.5e-25 88.6 1.6 4.8e-25 88.1 1.6 1.2 1 0 0 1 1 1 1 Peptidase S8 pro-domain L51_S25_CI-B8 PF05047.16 RUS91489.1 - 1.8e-11 43.8 0.7 4.7e-11 42.4 0.1 2.0 3 0 0 3 3 3 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TetR_C_24 PF17932.1 RUS91489.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Citrate_synt PF00285.21 RUS91490.1 - 2.1e-20 73.1 0.0 1.6e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Ion_trans PF00520.31 RUS91491.1 - 1.2e-16 60.7 21.5 1.6e-16 60.3 21.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RUS91491.1 - 9.2e-15 55.0 0.4 8.5e-09 35.9 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS91491.1 - 1.8e-13 50.4 1.2 2.2e-07 31.0 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91491.1 - 5.2e-13 47.9 0.7 0.037 14.6 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 RUS91491.1 - 1.5e-11 44.5 0.0 1.5e-06 28.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS91491.1 - 5.3e-11 42.4 0.4 0.0063 16.9 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.12 RUS91491.1 - 7.1e-10 38.1 12.5 7.1e-10 38.1 12.5 2.3 2 1 0 3 3 3 1 Polycystin cation channel Bac_export_2 PF01312.19 RUS91491.1 - 3 7.0 4.4 1.5 7.9 1.8 1.7 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family EI24 PF07264.11 RUS91491.1 - 3.1 8.0 13.1 15 5.8 13.2 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Lyase_aromatic PF00221.19 RUS91492.1 - 1.8e-165 551.1 0.4 1.7e-160 534.7 0.0 2.1 1 1 1 2 2 2 2 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 RUS91492.1 - 7e-10 39.0 0.1 1.9e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins HLH PF00010.26 RUS91494.1 - 3e-14 52.7 1.2 3e-14 52.7 1.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 RUS91494.1 - 6.3e-06 26.3 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Hairy Orange Otopetrin PF03189.13 RUS91494.1 - 1 8.1 4.2 0.75 8.6 0.0 2.4 2 1 0 2 2 2 0 Otopetrin TFIIA PF03153.13 RUS91494.1 - 1.3 9.0 45.3 0.044 13.8 16.2 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 RUS91496.1 - 0.0018 18.5 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 Orf78 (ac78) FAM176 PF14851.6 RUS91496.1 - 0.0061 16.2 0.3 0.012 15.3 0.3 1.6 1 0 0 1 1 1 1 FAM176 family SecE PF00584.20 RUS91496.1 - 0.0062 16.4 3.9 1e+02 3.0 0.0 4.7 4 1 3 7 7 6 0 SecE/Sec61-gamma subunits of protein translocation complex MAM33 PF02330.16 RUS91496.1 - 0.02 14.8 0.5 0.026 14.5 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein DUF3377 PF11857.8 RUS91496.1 - 0.037 14.0 4.4 0.082 12.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) GCIP PF13324.6 RUS91496.1 - 0.057 13.0 7.7 0.078 12.6 7.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 RUS91496.1 - 0.14 11.4 25.4 0.21 10.9 25.4 1.1 1 0 0 1 1 1 0 NOA36 protein Tmemb_9 PF05434.11 RUS91496.1 - 0.26 11.2 7.1 0.27 11.1 4.6 1.9 2 0 0 2 2 2 0 TMEM9 BUD22 PF09073.10 RUS91496.1 - 0.28 10.5 5.3 0.35 10.2 5.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 RUS91496.1 - 0.44 9.6 29.0 0.59 9.2 29.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 RUS91496.1 - 0.67 8.4 10.9 0.8 8.2 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 RUS91496.1 - 2.4 6.3 12.9 3.2 6.0 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SP_C-Propep PF08999.10 RUS91496.1 - 4.1 7.3 8.1 7.8 6.4 8.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide SDA1 PF05285.12 RUS91496.1 - 6.5 6.1 13.9 8.7 5.7 13.9 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 RUS91496.1 - 7.2 6.1 13.0 9.7 5.7 13.0 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 RUS91496.1 - 7.5 4.6 15.2 9.5 4.3 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family EphA2_TM PF14575.6 RUS91497.1 - 0.00078 20.3 0.0 0.0012 19.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 RUS91497.1 - 0.0045 17.6 1.2 0.0045 17.6 1.2 2.2 1 1 1 2 2 2 1 WW domain-binding protein 1 Podoplanin PF05808.11 RUS91497.1 - 0.0046 17.1 1.9 0.0085 16.2 1.9 1.4 1 0 0 1 1 1 1 Podoplanin Protocadherin PF08374.11 RUS91497.1 - 0.016 15.2 0.7 0.023 14.7 0.7 1.3 1 0 0 1 1 1 0 Protocadherin 7TM_GPCR_Srx PF10328.9 RUS91497.1 - 0.023 14.4 2.0 0.025 14.2 2.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DAP10 PF07213.11 RUS91497.1 - 0.025 14.5 0.8 0.044 13.7 0.8 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Adeno_E3_CR2 PF02439.15 RUS91497.1 - 0.026 14.3 12.1 0.063 13.0 12.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 RUS91497.1 - 0.053 13.4 1.1 0.073 13.0 1.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Myc_target_1 PF15179.6 RUS91497.1 - 0.06 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 Amnionless PF14828.6 RUS91497.1 - 0.079 11.8 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Cadherin_C_2 PF16492.5 RUS91497.1 - 0.1 13.3 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2207 PF09972.9 RUS91497.1 - 0.15 10.8 0.2 0.17 10.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 RUS91497.1 - 0.18 11.4 0.4 0.21 11.1 0.4 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 RUS91497.1 - 1.1 9.2 4.1 2 8.4 4.1 1.3 1 0 0 1 1 1 0 Syndecan domain Vpu PF00558.19 RUS91497.1 - 1.5 8.7 3.3 2.4 8.0 3.3 1.2 1 0 0 1 1 1 0 Vpu protein DUF2650 PF10853.8 RUS91497.1 - 2.3 8.0 14.8 31 4.4 14.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2650) SKG6 PF08693.10 RUS91497.1 - 3.2 7.3 14.1 5.1 6.6 14.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3827 PF12877.7 RUS91497.1 - 3.5 5.9 5.5 4.8 5.4 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Synaptobrevin PF00957.21 RUS91497.1 - 8.6 6.2 6.2 13 5.6 6.2 1.3 1 0 0 1 1 1 0 Synaptobrevin ADP_ribosyl_GH PF03747.14 RUS91499.1 - 7.1e-61 206.5 0.2 7.1e-61 206.5 0.2 1.3 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase DUF1540 PF07561.11 RUS91499.1 - 0.91 9.9 4.0 0.41 11.0 0.8 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) YmgB PF10798.8 RUS91500.1 - 1.6 8.6 26.2 45 4.0 1.3 6.9 1 1 3 4 4 4 0 Biofilm development protein YmgB/AriR rve PF00665.26 RUS91501.1 - 1.7e-19 70.2 0.0 3.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 RUS91501.1 - 3.1e-18 65.6 0.0 5.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 RUS91501.1 - 1.8e-13 50.4 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 RUS91501.1 - 9.5e-06 25.3 0.0 2.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 RUS91501.1 - 0.00079 19.6 0.1 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 RUS91501.1 - 0.00083 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVP PF00077.20 RUS91501.1 - 0.016 15.5 0.0 0.048 14.0 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease ADP_ribosyl_GH PF03747.14 RUS91502.1 - 1e-58 199.4 0.2 1.6e-58 198.8 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sde2_N_Ubi PF13019.6 RUS91502.1 - 0.66 9.8 2.6 1.8 8.4 2.6 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Ras PF00071.22 RUS91503.1 - 1.1e-23 83.7 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS91503.1 - 7.6e-12 45.5 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS91503.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 RUS91503.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3239 PF11580.8 RUS91503.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) Ycf70 PF17382.2 RUS91504.1 - 0.21 12.0 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Ycf70-like DUF229 PF02995.17 RUS91507.1 - 4.5e-92 309.2 0.1 2.4e-91 306.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 RUS91507.1 - 0.00022 20.7 0.1 0.00045 19.7 0.1 1.7 1 1 0 1 1 1 1 Sulfatase DUF2990 PF11693.8 RUS91508.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) C6_DPF PF10170.9 RUS91510.1 - 6e-31 106.7 12.3 6.8e-31 106.5 12.3 1.0 1 0 0 1 1 1 1 Cysteine-rich domain DAO PF01266.24 RUS91511.1 - 1.7e-49 169.3 0.0 1.9e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RUS91511.1 - 0.00037 19.8 0.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS91511.1 - 0.02 15.1 0.5 0.055 13.7 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RUS91511.1 - 0.063 13.8 0.6 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS91511.1 - 0.13 11.3 0.6 0.21 10.6 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Ras PF00071.22 RUS91512.1 - 5.5e-58 195.1 0.6 6.3e-58 194.9 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS91512.1 - 4.5e-35 120.5 0.2 6.6e-35 119.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS91512.1 - 3.1e-15 56.1 0.2 4e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RUS91512.1 - 0.00057 19.3 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS91512.1 - 0.004 16.7 0.5 0.015 14.9 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RUS91512.1 - 0.0073 16.4 0.2 0.0097 16.0 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RUS91512.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 RUS91512.1 - 0.018 15.3 0.2 0.034 14.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RUS91512.1 - 0.024 14.1 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 RUS91512.1 - 0.03 14.1 0.5 2 8.1 0.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 RUS91512.1 - 0.052 13.6 0.2 0.14 12.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RUS91512.1 - 0.052 13.9 0.1 0.076 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 RUS91512.1 - 0.057 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 RUS91512.1 - 0.068 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 NACHT domain Death_2 PF14786.6 RUS91512.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.6 1 1 1 2 2 2 0 Tube Death domain TniB PF05621.11 RUS91512.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 RUS91512.1 - 0.21 11.5 0.6 2.7 7.9 0.1 2.1 1 1 0 2 2 2 0 RsgA GTPase Tim17 PF02466.19 RUS91514.1 - 5.1e-28 97.7 4.6 8.1e-28 97.0 4.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M1 PF01433.20 RUS91516.1 - 6e-47 160.0 0.0 9e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RUS91516.1 - 4.8e-32 110.4 0.0 1.1e-31 109.2 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RUS91516.1 - 1.5e-24 87.3 0.0 2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 RUS91516.1 - 0.016 15.6 0.6 0.27 11.6 0.6 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M48 PF01435.18 RUS91516.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Acyl-CoA_dh_1 PF00441.24 RUS91517.1 - 2.2e-36 125.3 0.0 1.3e-35 122.9 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RUS91517.1 - 1.9e-27 95.3 0.3 4.1e-27 94.2 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RUS91517.1 - 2e-21 76.7 0.0 4.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RUS91517.1 - 3.4e-10 40.3 0.0 8.3e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Chlam_OMP PF01308.17 RUS91517.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia major outer membrane protein Ribosomal_L18A PF01775.17 RUS91518.1 - 4.2e-54 181.8 0.0 5.2e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A US30 PF17624.2 RUS91518.1 - 0.0016 17.5 0.4 0.0022 17.1 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function PNP_phzG_C PF10590.9 RUS91520.1 - 3.9 7.6 7.7 0.13 12.3 0.9 2.0 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Glyco_transf_10 PF00852.19 RUS91521.1 - 3.5e-40 137.6 0.0 5.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS91521.1 - 8.5e-17 61.6 0.0 2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Deltaretro_Tax PF05599.11 RUS91521.1 - 0.011 16.3 0.3 0.08 13.5 0.0 2.4 2 0 0 2 2 2 0 Deltaretrovirus Tax protein RRN3 PF05327.11 RUS91522.1 - 4.7e-05 22.1 15.5 6e-05 21.8 15.5 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RUS91522.1 - 0.0012 17.2 32.0 0.0017 16.7 32.0 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 RUS91522.1 - 0.021 13.1 24.9 0.035 12.4 24.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 RUS91522.1 - 0.21 10.0 25.9 0.36 9.2 25.9 1.3 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RUS91522.1 - 0.24 10.8 38.8 0.022 14.2 34.2 1.5 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 RUS91522.1 - 2.3 7.5 34.4 0.73 9.1 31.8 1.4 2 0 0 2 2 2 0 BUD22 DUF913 PF06025.12 RUS91522.1 - 4.2 6.2 4.5 8 5.3 4.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 RUS91522.1 - 4.7 7.0 14.7 7.2 6.4 13.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein NPR3 PF03666.13 RUS91522.1 - 8.8 5.0 11.2 14 4.3 11.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cyclin_N PF00134.23 RUS91523.1 - 3.6e-34 117.3 1.3 7.6e-34 116.2 1.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RUS91523.1 - 3e-14 53.1 5.6 1e-12 48.2 0.2 3.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 RUS91523.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain K-cyclin_vir_C PF09080.10 RUS91523.1 - 0.099 13.1 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 K cyclin, C terminal DUF678 PF05077.12 RUS91523.1 - 0.28 11.3 3.0 0.31 11.2 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Ribosomal_S2 PF00318.20 RUS91524.1 - 3.9e-25 88.4 0.0 5.3e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 RUS91524.1 - 1.4e-10 42.4 10.4 2.3e-10 41.7 10.4 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus DSL PF01414.19 RUS91525.1 - 5.7e-08 32.9 7.8 6.8e-08 32.7 0.5 2.6 2 0 0 2 2 2 1 Delta serrate ligand MS_channel PF00924.18 RUS91525.1 - 0.089 12.3 8.9 0.14 11.6 8.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel MCM_bind PF09739.9 RUS91525.1 - 2.1 6.7 5.8 2.9 6.2 5.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor 7tm_1 PF00001.21 RUS91526.1 - 2.5e-29 102.4 13.1 2.9e-29 102.2 13.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91526.1 - 5e-12 45.7 13.0 6.1e-12 45.5 13.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS91526.1 - 0.00051 19.7 3.7 0.00051 19.7 3.7 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Tmemb_55A PF09788.9 RUS91526.1 - 0.064 12.3 0.9 0.34 10.0 0.9 2.0 1 1 1 2 2 2 0 Transmembrane protein 55A CS PF04969.16 RUS91527.1 - 0.32 12.0 3.8 28 5.8 0.1 3.2 1 1 1 3 3 3 0 CS domain YSIRK_signal PF04650.17 RUS91527.1 - 0.33 10.9 5.8 6.6 6.7 0.6 2.3 2 0 0 2 2 2 0 YSIRK type signal peptide Coronavirus_5 PF05528.11 RUS91527.1 - 4.6 7.3 12.2 0.39 10.7 1.6 2.5 1 1 1 2 2 2 0 Coronavirus gene 5 protein HMG_box PF00505.19 RUS91528.1 - 2.9e-16 59.7 1.0 5.3e-16 58.8 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RUS91528.1 - 3e-06 27.7 1.0 6.4e-06 26.7 1.0 1.5 1 0 0 1 1 1 1 HMG-box domain MlaC PF05494.12 RUS91528.1 - 0.00043 20.1 0.1 0.0079 16.0 0.0 2.2 2 0 0 2 2 2 1 MlaC protein SWI-SNF_Ssr4 PF08549.10 RUS91528.1 - 0.016 13.9 0.8 0.023 13.3 0.8 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ProQ PF04352.13 RUS91528.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 ProQ/FINO family DUF3510 PF12022.8 RUS91529.1 - 0.017 15.5 0.2 0.026 14.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) BLOC1_2 PF10046.9 RUS91529.1 - 0.1 12.9 1.6 0.15 12.3 1.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 G_path_suppress PF15991.5 RUS91529.1 - 0.14 12.2 2.6 0.18 11.9 2.6 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor DUF4429 PF14472.6 RUS91530.1 - 0.023 15.2 1.0 0.14 12.7 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4429) PT PF04886.12 RUS91531.1 - 5.5e-07 29.0 41.2 0.0042 16.6 14.1 5.0 3 1 1 4 4 4 4 PT repeat PWI PF01480.17 RUS91533.1 - 3.8e-27 94.4 0.1 7.6e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 PWI domain PPP1R32 PF15691.5 RUS91534.1 - 6.5e-111 371.4 5.2 2.7e-59 201.4 0.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 1 regulatory subunit 32 zf-C4H2 PF10146.9 RUS91535.1 - 6.5e-74 248.8 19.9 7.5e-74 248.6 19.9 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 RUS91535.1 - 0.008 16.2 0.9 0.016 15.2 0.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 RUS91535.1 - 0.054 13.4 4.2 0.12 12.3 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 RUS91535.1 - 0.093 12.4 2.2 0.17 11.5 2.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 RUS91535.1 - 0.095 12.5 2.7 0.22 11.3 2.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4404 PF14357.6 RUS91535.1 - 0.12 13.0 5.9 0.67 10.6 5.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Peptidase_C48 PF02902.19 RUS91536.1 - 8.6e-40 136.9 0.8 1.6e-39 136.0 0.8 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1258 PF06869.12 RUS91536.1 - 0.73 9.3 2.6 6.3 6.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) GCV_T PF01571.21 RUS91537.1 - 7.6e-10 38.6 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain NPV_P10 PF05531.12 RUS91538.1 - 0.0028 18.1 1.4 0.0028 18.1 1.4 2.9 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein RPW8 PF05659.11 RUS91538.1 - 0.01 15.5 1.9 0.01 15.5 1.9 1.9 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 RUS91538.1 - 0.31 11.1 11.3 0.22 11.5 4.2 2.7 1 1 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 RUS91538.1 - 2.4 8.5 25.1 1.8 9.0 9.6 2.3 1 1 1 2 2 2 0 Fez1 COG2 PF06148.11 RUS91538.1 - 4.1 7.5 10.1 1.4 9.0 3.1 2.8 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 RUS91538.1 - 4.6 6.0 26.4 0.047 12.6 10.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 RUS91538.1 - 10 6.3 24.4 9.4 6.4 7.5 2.6 1 1 0 2 2 2 0 Tropomyosin like MOLO1 PF17175.4 RUS91539.1 - 2.6e-20 72.7 0.4 3.6e-20 72.3 0.4 1.2 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 RUS91539.1 - 0.00025 21.2 0.0 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 TPM domain 7tm_1 PF00001.21 RUS91540.1 - 2.5e-05 23.7 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3943 PF13084.6 RUS91543.1 - 0.064 13.1 0.1 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) WD40 PF00400.32 RUS91544.1 - 3.7e-38 128.9 14.8 4.2e-08 33.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91544.1 - 8.7e-10 38.8 0.2 0.45 10.8 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RUS91544.1 - 0.0022 17.6 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 PQQ-like domain Na_K-ATPase PF00287.18 RUS91545.1 - 3e-15 56.1 0.2 4e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Lectin_N PF03954.14 RUS91545.1 - 0.099 12.4 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SH3_1 PF00018.28 RUS91546.1 - 3.8e-19 68.0 0.6 9.1e-07 28.4 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 RUS91546.1 - 6.9e-19 67.5 0.9 2.7e-07 30.4 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 RUS91546.1 - 1.8e-13 50.0 0.0 0.00018 21.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 RUS91546.1 - 0.0071 16.6 0.1 3.9 7.8 0.0 2.9 3 0 0 3 3 3 2 Bacterial SH3 domain hSH3 PF14603.6 RUS91546.1 - 0.046 14.2 0.0 6 7.4 0.0 2.4 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_10 PF17902.1 RUS91546.1 - 0.058 13.5 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 SH3 domain PGK PF00162.19 RUS91547.1 - 5.2e-186 618.1 0.0 1.1e-105 353.8 0.0 2.7 2 1 0 2 2 2 2 Phosphoglycerate kinase HLH PF00010.26 RUS91548.1 - 2.3e-15 56.3 2.7 2.3e-15 56.3 2.7 2.6 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain RNA_pol_Rpb6 PF01192.22 RUS91548.1 - 0.091 12.7 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb6 DUF1647 PF07801.11 RUS91549.1 - 2.7e-11 43.4 0.2 4.6e-11 42.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) DUF2935 PF11155.8 RUS91549.1 - 0.0082 16.5 0.3 1.8 8.9 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF2935) Alk_phosphatase PF00245.20 RUS91551.1 - 9.2e-101 337.8 0.0 1.2e-100 337.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 RUS91551.1 - 4.4e-05 23.0 0.0 6.1e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Metalloenzyme superfamily FAM27 PF15832.5 RUS91551.1 - 0.017 15.7 4.7 0.037 14.5 3.9 1.9 2 0 0 2 2 2 0 FAM27 D and E protein family DUF3915 PF13054.6 RUS91551.1 - 1.3 9.0 8.2 4.6 7.2 8.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 RUS91551.1 - 3.2 5.9 12.9 4.6 5.4 12.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family p450 PF00067.22 RUS91552.1 - 7.8e-73 245.8 0.0 9.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4460 PF14687.6 RUS91552.1 - 0.39 10.8 4.2 2.7 8.1 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) 7tm_1 PF00001.21 RUS91553.1 - 4.4e-46 157.4 17.3 4.4e-46 157.4 17.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91553.1 - 1.7e-11 44.0 18.6 1.7e-11 44.0 18.6 1.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS91553.1 - 4.6e-06 26.4 20.3 9.4e-06 25.4 19.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 RUS91553.1 - 0.0027 17.5 10.3 0.0027 17.5 10.3 2.0 2 0 0 2 2 2 1 Olfactory receptor PRA1 PF03208.19 RUS91553.1 - 0.31 10.7 0.0 0.31 10.7 0.0 3.4 2 2 1 3 3 3 0 PRA1 family protein DUF2834 PF11196.8 RUS91553.1 - 1.5 9.2 13.4 0.32 11.4 7.5 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2834) RNA_pol_Rpb2_6 PF00562.28 RUS91554.1 - 9.2e-118 393.7 0.0 2e-117 392.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RUS91554.1 - 1.2e-38 132.7 0.1 1.8e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 RUS91554.1 - 6.7e-29 99.9 0.0 1.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 RUS91554.1 - 3.3e-24 85.1 0.0 9.4e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 RUS91554.1 - 4.7e-19 68.1 0.0 1.1e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 RUS91554.1 - 2.3e-12 47.0 0.0 8.4e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 zinc_ribbon_15 PF17032.5 RUS91554.1 - 0.11 13.2 2.2 0.3 11.8 2.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 RUS91554.1 - 0.87 9.7 3.2 1.1 9.4 0.9 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C4pol PF14260.6 RUS91554.1 - 1.9 9.0 5.6 4.2 7.9 5.6 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Myofilin PF15929.5 RUS91555.1 - 0.038 14.4 4.3 0.1 13.0 4.1 1.7 1 1 0 1 1 1 0 Myofilin Sod_Cu PF00080.20 RUS91556.1 - 0.014 15.6 0.3 0.063 13.4 0.1 1.9 1 1 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) SDA1 PF05285.12 RUS91557.1 - 0.043 13.2 51.5 0.048 13.1 51.5 1.2 1 0 0 1 1 1 0 SDA1 LSDAT_euk PF18139.1 RUS91557.1 - 0.24 10.8 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM SAPS PF04499.15 RUS91557.1 - 3.3 6.4 18.3 3.9 6.2 18.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 RUS91557.1 - 5.8 6.1 46.5 7.2 5.8 46.5 1.3 1 0 0 1 1 1 0 BUD22 LSDAT_euk PF18139.1 RUS91558.1 - 8.3e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 RUS91558.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Aida_N PF08910.10 RUS91559.1 - 0.16 12.3 1.9 0.41 11.1 1.9 1.6 1 0 0 1 1 1 0 Aida N-terminus Fib_alpha PF08702.10 RUS91559.1 - 0.46 10.7 5.8 0.79 9.9 5.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sod_Cu PF00080.20 RUS91560.1 - 1.3e-17 64.3 0.1 1.5e-11 44.6 0.0 4.5 5 0 0 5 5 5 3 Copper/zinc superoxide dismutase (SODC) Big_3_5 PF16640.5 RUS91560.1 - 1.2 9.4 4.2 5.9 7.1 0.7 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) AAA PF00004.29 RUS91561.1 - 1.8e-40 138.5 0.0 4.4e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RUS91561.1 - 1.4e-19 69.8 0.0 3.4e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RUS91561.1 - 2.5e-10 40.0 2.0 2.7e-10 39.9 0.4 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 RUS91561.1 - 2.9e-06 27.8 0.8 0.0012 19.2 0.1 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 RUS91561.1 - 1.7e-05 24.8 0.6 0.00013 22.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 RUS91561.1 - 0.00013 21.2 0.2 0.00037 19.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RUS91561.1 - 0.00021 21.0 0.0 0.00056 19.7 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RUS91561.1 - 0.0016 18.5 2.8 0.0025 18.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RUS91561.1 - 0.0029 17.9 0.4 0.1 12.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 RUS91561.1 - 0.029 13.7 0.7 0.1 12.0 0.0 2.2 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 RUS91561.1 - 0.038 13.4 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 RUS91561.1 - 0.038 13.8 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 RUS91561.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RUS91561.1 - 0.054 13.0 0.2 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 RUS91561.1 - 0.07 13.0 0.5 2 8.3 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 RUS91561.1 - 0.079 12.5 1.5 0.4 10.2 0.4 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RUS91561.1 - 0.092 12.4 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 RUS91561.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RUS91561.1 - 0.1 13.2 0.0 0.38 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RUS91561.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 RUS91561.1 - 0.11 12.1 0.0 0.33 10.4 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RUS91561.1 - 0.23 11.1 1.8 0.37 10.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain eIF-5a PF01287.20 RUS91562.1 - 0.056 13.6 1.6 0.3 11.2 0.5 2.6 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Transglut_core PF01841.19 RUS91563.1 - 0.0029 18.0 0.0 0.005 17.3 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily LRR_8 PF13855.6 RUS91564.1 - 5.8e-28 96.4 25.3 9.7e-09 34.9 0.9 6.6 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS91564.1 - 2.5e-18 65.9 28.5 0.0012 19.2 2.7 8.0 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) COR PF16095.5 RUS91564.1 - 3e-15 56.6 0.0 7.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ank_2 PF12796.7 RUS91564.1 - 9.1e-12 45.4 0.3 4.7e-07 30.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91564.1 - 1.5e-06 28.7 1.6 0.13 12.9 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91564.1 - 4.6e-06 26.6 0.3 0.07 13.7 0.0 4.5 4 0 0 4 4 3 1 Ankyrin repeat LRR_1 PF00560.33 RUS91564.1 - 0.00023 21.3 24.9 28 5.8 0.0 10.8 12 0 0 12 12 10 0 Leucine Rich Repeat Ank_5 PF13857.6 RUS91564.1 - 0.00036 20.8 2.5 0.0073 16.6 0.1 3.3 4 0 0 4 4 3 1 Ankyrin repeats (many copies) LRR_6 PF13516.6 RUS91564.1 - 0.0016 18.4 23.0 0.071 13.2 0.0 6.9 8 0 0 8 8 8 2 Leucine Rich repeat Ank PF00023.30 RUS91564.1 - 0.02 15.3 0.0 7.3 7.2 0.0 3.3 3 0 0 3 3 2 0 Ankyrin repeat PAH PF02671.21 RUS91564.1 - 0.14 12.3 0.0 0.64 10.2 0.0 2.1 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF3763 PF12592.8 RUS91564.1 - 0.55 10.3 2.5 27 4.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Pkinase PF00069.25 RUS91565.1 - 7.6e-32 110.7 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91565.1 - 2.7e-24 85.9 0.0 3.7e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 RUS91565.1 - 0.081 11.9 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.32 RUS91566.1 - 1.4e-15 57.3 6.5 6.4e-06 26.8 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91566.1 - 0.0009 19.5 0.0 0.067 13.5 0.0 3.3 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Sugar_tr PF00083.24 RUS91567.1 - 1.6e-35 122.9 17.4 5.3e-26 91.5 1.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RUS91567.1 - 1.2e-32 113.3 29.9 3.5e-29 101.8 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2635 PF10948.8 RUS91567.1 - 0.0098 15.6 0.7 0.056 13.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2635) ETRAMP PF09716.10 RUS91568.1 - 0.00029 20.8 0.3 0.016 15.3 0.1 2.3 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Cadherin_C_2 PF16492.5 RUS91568.1 - 0.0013 19.4 0.0 0.033 14.9 0.0 2.2 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 RUS91568.1 - 0.0018 19.1 0.1 0.063 14.2 0.1 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 RUS91568.1 - 0.0056 17.1 0.9 0.0056 17.1 0.9 2.1 2 0 0 2 2 2 1 FAM163 family FAM176 PF14851.6 RUS91568.1 - 0.02 14.6 0.4 0.047 13.3 0.1 1.7 2 0 0 2 2 2 0 FAM176 family Orthoreo_P10 PF07204.11 RUS91568.1 - 0.043 13.8 2.6 0.051 13.5 0.7 2.0 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 TssO PF17561.2 RUS91568.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO TMIE PF16038.5 RUS91568.1 - 0.1 12.5 1.3 0.22 11.4 1.3 1.5 1 0 0 1 1 1 0 TMIE protein Prominin PF05478.11 RUS91568.1 - 0.12 10.3 3.3 0.17 9.8 3.3 1.1 1 0 0 1 1 1 0 Prominin Synaphin PF05835.12 RUS91568.1 - 0.98 9.7 9.5 1.4 9.2 9.5 1.1 1 0 0 1 1 1 0 Synaphin protein ETF PF01012.21 RUS91569.1 - 4.2e-43 147.4 1.0 6.4e-43 146.7 1.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 RUS91569.1 - 2.3e-37 126.9 2.2 3.6e-37 126.2 0.5 2.3 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain Misat_Tub_SegII PF10644.9 RUS91570.1 - 1.1e-37 129.0 0.0 2.4e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RUS91570.1 - 1.6e-27 96.4 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 RUS91570.1 - 1e-13 51.9 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF4430 PF14478.6 RUS91571.1 - 0.0013 19.3 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) DUF4062 PF13271.6 RUS91572.1 - 8.8e-11 42.0 0.0 6e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) NACHT PF05729.12 RUS91572.1 - 1.1e-10 41.7 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 RUS91572.1 - 2.9e-09 37.5 0.0 8.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.32 RUS91572.1 - 3.5e-08 34.0 0.4 0.0039 18.0 0.1 5.7 6 0 0 6 6 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91572.1 - 9.5e-05 22.6 0.9 1.3 9.4 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain APAF1_C PF17908.1 RUS91572.1 - 0.00049 20.1 0.3 0.0015 18.5 0.3 1.8 1 0 0 1 1 1 1 APAF-1 helical domain AAA PF00004.29 RUS91572.1 - 0.00065 20.1 0.1 0.0071 16.8 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PALB2_WD40 PF16756.5 RUS91572.1 - 0.0019 17.2 1.7 0.048 12.6 0.0 3.2 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain ATPase_2 PF01637.18 RUS91572.1 - 0.003 17.5 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 RUS91572.1 - 0.0031 17.8 0.0 0.0097 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RUS91572.1 - 0.0038 16.8 0.0 0.25 10.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RUS91572.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain HPS3_N PF14761.6 RUS91572.1 - 0.11 12.1 0.1 7.6 6.0 0.1 2.7 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 WD40 PF00400.32 RUS91573.1 - 5.4e-11 42.9 3.7 0.15 13.0 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91573.1 - 0.00057 20.1 0.2 3.7 7.9 0.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 RUS91573.1 - 0.02 13.7 1.7 0.36 9.5 0.1 2.3 1 1 1 2 2 2 0 Nup133 N terminal like 7tm_2 PF00002.24 RUS91575.1 - 4.3e-26 91.7 17.6 6.1e-26 91.2 17.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CrgA PF06781.12 RUS91575.1 - 0.096 12.8 0.9 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Cell division protein CrgA DUF3867 PF12983.7 RUS91575.1 - 0.24 11.4 1.8 0.18 11.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) 7tm_2 PF00002.24 RUS91577.1 - 6.9e-25 87.8 17.8 1e-24 87.2 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) CrgA PF06781.12 RUS91577.1 - 0.2 11.8 1.8 2.5 8.2 0.2 3.2 3 0 0 3 3 3 0 Cell division protein CrgA DUF2207 PF09972.9 RUS91577.1 - 2.3 6.9 8.2 3.4 6.3 0.3 2.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Perilipin PF03036.16 RUS91579.1 - 3.3e-38 131.8 4.7 4.2e-38 131.4 4.7 1.1 1 0 0 1 1 1 1 Perilipin family RINT1_TIP1 PF04437.13 RUS91579.1 - 0.057 12.3 1.2 0.18 10.6 0.1 2.0 2 0 0 2 2 2 0 RINT-1 / TIP-1 family Fib_alpha PF08702.10 RUS91579.1 - 0.11 12.7 6.8 1 9.6 0.6 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ASC PF00858.24 RUS91580.1 - 3.1e-75 253.8 7.8 3.5e-65 220.7 4.5 2.0 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel PSI PF01437.25 RUS91581.1 - 0.13 12.8 12.7 0.27 11.8 12.7 1.6 1 0 0 1 1 1 0 Plexin repeat DUF2749 PF10907.8 RUS91581.1 - 0.17 12.1 0.1 0.57 10.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) MGC-24 PF05283.11 RUS91581.1 - 2.1 8.8 15.7 0.056 13.9 8.4 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Integrin_alpha2 PF08441.12 RUS91582.1 - 3.2e-74 250.5 0.2 4.4e-74 250.1 0.2 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 RUS91582.1 - 3.4e-12 46.3 18.5 4.9e-08 33.0 3.6 4.7 5 0 0 5 5 5 2 FG-GAP repeat VCBS PF13517.6 RUS91582.1 - 3.7e-10 40.2 10.8 2.2e-08 34.5 0.4 4.1 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 RUS91582.1 - 0.002 18.3 9.4 5.9 7.2 0.0 5.9 6 0 0 6 6 6 2 FG-GAP repeat Integrin_alpha PF00357.20 RUS91582.1 - 0.0043 16.9 0.5 0.011 15.7 0.5 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region Rubredoxin_2 PF18073.1 RUS91582.1 - 0.07 12.9 1.0 0.47 10.2 1.0 2.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain MLANA PF14991.6 RUS91582.1 - 0.12 12.7 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein melan-A CARDB PF07705.11 RUS91582.1 - 0.46 10.8 4.0 2.8 8.3 0.0 2.9 2 0 0 2 2 2 0 CARDB Cys_knot PF00007.22 RUS91583.1 - 1.8e-07 31.4 11.4 2.6e-07 30.9 11.4 1.2 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 RUS91583.1 - 1.4e-06 28.3 12.1 1.9e-06 27.8 12.1 1.2 1 0 0 1 1 1 1 DAN domain MIP PF00230.20 RUS91584.1 - 0.0002 21.2 3.4 0.0002 21.2 3.4 1.6 1 1 0 1 1 1 1 Major intrinsic protein 7tm_7 PF08395.12 RUS91584.1 - 0.0048 16.1 1.8 0.0071 15.6 1.8 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor Ank_2 PF12796.7 RUS91585.1 - 4.6e-10 39.9 0.8 2.1e-07 31.4 0.3 4.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS91585.1 - 2.9e-05 24.1 2.3 0.65 10.7 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 RUS91585.1 - 0.00031 21.0 1.8 2.6 8.6 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 RUS91585.1 - 0.004 17.4 0.4 0.23 11.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS91585.1 - 0.028 15.0 0.4 0.63 10.7 0.1 3.2 3 1 0 3 3 3 0 Ankyrin repeats (many copies) PKD_2 PF16407.5 RUS91585.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 PKD-like family Cnd3 PF12719.7 RUS91586.1 - 7.2e-74 248.6 2.7 7.2e-74 248.6 2.7 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 RUS91586.1 - 1.9e-11 44.2 2.9 0.018 15.4 0.0 5.5 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 RUS91586.1 - 2.4e-07 30.4 13.0 2.7 8.5 0.0 8.2 8 0 0 8 8 8 3 HEAT repeat Cnd1 PF12717.7 RUS91586.1 - 1.1e-05 25.5 14.2 0.084 12.9 0.8 5.7 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 UVR PF02151.19 RUS91586.1 - 2.3e-05 24.0 0.1 6.9e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif HEAT_EZ PF13513.6 RUS91586.1 - 0.0036 17.8 11.2 0.52 10.9 0.1 6.1 6 2 2 8 8 8 2 HEAT-like repeat HlyD_2 PF12700.7 RUS91586.1 - 0.021 13.6 1.8 0.035 12.8 1.8 1.3 1 0 0 1 1 1 0 HlyD family secretion protein ParcG PF10274.9 RUS91586.1 - 0.055 13.6 2.1 0.3 11.2 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein DUF1981 PF09324.10 RUS91586.1 - 0.08 12.8 0.8 18 5.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) NopRA1 PF16201.5 RUS91586.1 - 0.084 12.5 0.8 2.5 7.6 0.3 2.9 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 DUF4363 PF14276.6 RUS91586.1 - 1.1 9.3 5.8 2.1 8.5 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Tai4 PF16695.5 RUS91587.1 - 0.025 15.1 4.6 4.5 7.9 0.5 2.9 1 1 2 3 3 3 0 Type VI secretion system (T6SS), amidase immunity protein Integrase_H2C2 PF17921.1 RUS91587.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain DUF1427 PF07235.11 RUS91587.1 - 0.48 10.4 5.2 15 5.6 0.4 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1427) Lipoprotein_22 PF17294.2 RUS91587.1 - 4.4 6.9 15.8 7.4 6.2 1.7 3.0 1 1 3 4 4 4 0 Uncharacterised lipoprotein family Asp-B-Hydro_N PF05279.11 RUS91587.1 - 9.2 6.2 14.7 11 6.0 14.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3763 PF12592.8 RUS91588.1 - 5.3e-09 36.0 3.5 16 5.7 0.0 7.8 1 1 7 8 8 8 1 Protein of unknown function (DUF3763) DUF4710 PF15828.5 RUS91588.1 - 0.28 11.3 5.8 76 3.5 0.1 4.5 1 1 5 6 6 6 0 Domain of unknown function (DUF4710) Leu_leader PF08054.11 RUS91588.1 - 2.8 7.6 12.5 3.1e+02 1.1 0.0 6.8 9 0 0 9 9 9 0 Leucine operon leader peptide Fibrinogen_C PF00147.18 RUS91589.1 - 1.9e-63 214.2 9.4 2.9e-63 213.6 9.4 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CdvA PF18822.1 RUS91589.1 - 2.1e-05 24.3 3.6 7.7e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 CdvA-like coiled-coil domain FPP PF05911.11 RUS91589.1 - 0.00022 19.6 4.8 0.00031 19.1 4.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 RUS91589.1 - 0.00028 20.9 12.2 0.012 15.7 2.5 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 RUS91589.1 - 0.0011 18.7 6.8 0.023 14.5 0.3 3.4 2 1 1 3 3 3 1 Nsp1-like C-terminal region Synaptonemal_3 PF15191.6 RUS91589.1 - 0.0035 17.1 0.2 0.0095 15.7 0.2 1.7 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 HSBP1 PF06825.12 RUS91589.1 - 0.024 14.5 2.8 0.033 14.0 0.3 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Glyco_hydro_3_C PF01915.22 RUS91589.1 - 0.025 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TFR_dimer PF04253.15 RUS91589.1 - 0.18 11.9 2.5 0.39 10.8 0.2 2.5 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain Laminin_II PF06009.12 RUS91589.1 - 0.34 10.9 7.6 6.5 6.8 0.8 3.3 2 1 1 3 3 3 0 Laminin Domain II MscS_porin PF12795.7 RUS91589.1 - 0.4 10.2 11.1 0.96 8.9 3.1 3.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HR1 PF02185.16 RUS91589.1 - 0.79 9.9 7.9 16 5.7 0.0 3.9 4 0 0 4 4 4 0 Hr1 repeat CENP-F_leu_zip PF10473.9 RUS91589.1 - 0.99 9.4 17.1 2.2 8.3 1.8 3.4 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 RUS91589.1 - 1.2 9.2 4.6 0.77 9.9 0.2 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF3287 PF11690.8 RUS91589.1 - 1.7 8.4 4.7 6.4 6.5 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Cortex-I_coil PF09304.10 RUS91589.1 - 2.1 8.6 9.8 3.6 7.9 2.7 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil Atg14 PF10186.9 RUS91589.1 - 8 5.4 7.1 0.49 9.4 1.7 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 RUS91589.1 - 8.2 7.0 11.4 12 6.5 0.3 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.6 RUS91589.1 - 9.7 6.4 11.6 7.3 6.8 4.6 2.7 2 1 0 2 2 2 0 Up-regulated During Septation MFS_1 PF07690.16 RUS91590.1 - 1.4e-15 57.1 34.7 1.7e-12 46.9 27.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 RUS91590.1 - 0.0016 17.0 8.0 0.061 11.8 0.7 2.3 1 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Lectin_N PF03954.14 RUS91590.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1129 PF06570.11 RUS91590.1 - 1.4 8.4 13.2 0.035 13.6 3.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Sec20 PF03908.13 RUS91591.1 - 0.18 11.7 0.6 0.49 10.3 0.6 1.7 1 0 0 1 1 1 0 Sec20 T2SS-T3SS_pil_N PF13629.6 RUS91592.1 - 0.11 12.2 0.3 9.9 6.0 0.1 2.8 3 0 0 3 3 3 0 Pilus formation protein N terminal region GFRP PF06399.13 RUS91595.1 - 0.055 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF4717 PF15838.5 RUS91595.1 - 0.11 12.6 0.6 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) TUDOR PF00567.24 RUS91596.1 - 2e-12 47.2 0.3 1.4e-06 28.3 0.1 2.9 2 1 0 2 2 2 2 Tudor domain TUDOR PF00567.24 RUS91597.1 - 7.3e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 RUS91597.1 - 0.00026 21.4 0.0 0.00081 19.8 0.0 1.9 2 0 0 2 2 2 1 Agenet domain Dmrt1 PF12374.8 RUS91597.1 - 0.94 10.0 7.6 0.85 10.1 2.1 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 OST-HTH PF12872.7 RUS91598.1 - 5.3e-05 23.0 0.1 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 1 OST-HTH/LOTUS domain Ndc1_Nup PF09531.10 RUS91598.1 - 1.3 7.6 2.8 1.9 7.0 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S9_N PF02897.15 RUS91599.1 - 9.9e-143 475.9 0.5 1.3e-142 475.5 0.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RUS91599.1 - 1e-65 221.2 0.0 1.6e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Fibrinogen_C PF00147.18 RUS91600.1 - 2.6e-37 128.8 3.2 3.2e-37 128.5 3.2 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Toxin_22 PF08092.11 RUS91600.1 - 0.079 13.0 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Magi peptide toxin family Glyco_transf_10 PF00852.19 RUS91601.1 - 6.2e-41 140.1 0.5 1.1e-40 139.2 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 RUS91601.1 - 4.5e-17 62.5 0.1 9.5e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal TMEM18 PF14770.6 RUS91602.1 - 8.2e-45 151.6 2.0 1e-44 151.3 2.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 PLD_C PF12357.8 RUS91602.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase D C terminal Tetraspanin PF00335.20 RUS91602.1 - 0.2 11.3 2.3 0.67 9.6 0.8 1.9 1 1 0 2 2 2 0 Tetraspanin family RcsF PF16358.5 RUS91603.1 - 2.9e-22 78.8 0.1 8.2 6.5 0.0 12.6 1 1 12 15 15 15 13 RcsF lipoprotein DUF1697 PF08002.11 RUS91603.1 - 2.4e-10 41.0 1.5 15 6.0 0.0 6.7 1 1 11 12 12 12 2 Protein of unknown function (DUF1697) DUF948 PF06103.11 RUS91603.1 - 8.5e-05 22.7 39.9 32 4.9 1.5 11.2 1 1 6 7 7 7 0 Bacterial protein of unknown function (DUF948) ATP-synt_F6 PF05511.11 RUS91603.1 - 0.00015 22.1 0.0 67 4.0 0.0 5.4 1 1 10 11 11 11 0 Mitochondrial ATP synthase coupling factor 6 TraV PF09676.10 RUS91603.1 - 0.075 14.0 24.9 59 4.7 0.6 7.0 1 1 8 9 9 9 0 Type IV conjugative transfer system lipoprotein (TraV) 7TMR-HDED PF07697.11 RUS91603.1 - 0.28 11.3 6.5 29 4.7 6.5 3.4 1 1 0 1 1 1 0 7TM-HD extracellular DUF4478 PF14793.6 RUS91603.1 - 0.86 9.5 6.1 52 3.8 0.1 6.2 2 2 8 11 11 11 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases TAF6_C PF07571.13 RUS91603.1 - 4.5 7.7 6.9 3.4e+02 1.6 6.9 4.5 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain SKG6 PF08693.10 RUS91604.1 - 0.0038 16.6 3.5 0.0062 15.9 3.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 RUS91604.1 - 0.024 14.5 0.6 0.053 13.4 0.6 1.6 1 0 0 1 1 1 0 Syndecan domain PAP_PilO PF06864.12 RUS91604.1 - 0.098 11.5 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Pilin accessory protein (PilO) EphA2_TM PF14575.6 RUS91604.1 - 0.22 12.4 0.8 0.48 11.3 0.8 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fibrinogen_C PF00147.18 RUS91606.1 - 7.7e-57 192.6 8.1 1.6e-56 191.6 8.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Borrelia_REV PF03978.13 RUS91606.1 - 0.00031 20.8 2.1 0.00067 19.6 1.4 1.8 1 1 1 2 2 2 1 Borrelia burgdorferi REV protein Apolipoprotein PF01442.18 RUS91606.1 - 0.0018 18.2 2.3 0.0034 17.3 2.3 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 RUS91606.1 - 0.021 14.4 1.9 0.03 13.9 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2884 PF11101.8 RUS91606.1 - 0.045 13.2 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) OmpH PF03938.14 RUS91606.1 - 0.17 12.2 1.0 0.29 11.5 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4795 PF16043.5 RUS91606.1 - 0.18 11.4 4.0 0.055 13.1 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SF-assemblin PF06705.11 RUS91606.1 - 0.26 10.6 3.4 7 5.9 4.0 2.2 1 1 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 RUS91606.1 - 0.56 10.2 2.8 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med15 PF09606.10 RUS91607.1 - 0.0023 16.7 34.9 0.0025 16.6 34.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 RUS91607.1 - 0.01 14.1 29.4 0.012 13.9 29.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 RUS91607.1 - 0.022 11.9 27.2 0.029 11.5 27.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 RUS91607.1 - 0.079 11.9 10.1 0.094 11.6 10.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EMC3_TMCO1 PF01956.16 RUS91607.1 - 0.23 11.2 6.0 0.38 10.5 6.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FAM60A PF15396.6 RUS91607.1 - 0.37 10.8 18.2 0.65 10.0 18.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.13 RUS91607.1 - 0.66 9.5 20.6 1 8.9 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABC2_membrane_2 PF12679.7 RUS91607.1 - 0.7 9.1 2.7 1 8.6 2.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MMPL PF03176.15 RUS91607.1 - 0.83 8.5 5.6 1.3 7.8 5.6 1.3 1 0 0 1 1 1 0 MMPL family Hamartin PF04388.12 RUS91607.1 - 1.1 7.8 20.0 1.2 7.7 20.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF5523 PF17661.1 RUS91607.1 - 1.4 8.6 20.9 2.2 7.9 20.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Hid1 PF12722.7 RUS91607.1 - 1.7 6.7 23.2 2.1 6.4 23.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 RUS91607.1 - 2.3 6.0 15.2 3.3 5.5 15.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4551 PF15087.6 RUS91607.1 - 5.5 5.7 20.3 6.6 5.4 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) T-box PF00907.22 RUS91608.1 - 7.1e-39 134.0 0.1 4.6e-38 131.3 0.1 2.2 1 1 0 1 1 1 1 T-box dsrm PF00035.26 RUS91611.1 - 1.3e-46 157.1 4.6 8.7e-13 48.8 0.0 6.4 6 0 0 6 6 6 5 Double-stranded RNA binding motif Staufen_C PF16482.5 RUS91611.1 - 9.7e-09 35.4 12.2 1.4e-08 34.8 0.0 5.2 5 2 1 6 6 6 2 Staufen C-terminal domain DND1_DSRM PF14709.7 RUS91611.1 - 0.00022 21.4 4.9 0.08 13.2 0.1 5.3 5 1 0 5 5 5 1 double strand RNA binding domain from DEAD END PROTEIN 1 F-box-like PF12937.7 RUS91612.1 - 8.8e-09 35.1 4.0 1.5e-08 34.4 4.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RUS91612.1 - 1.8e-07 30.9 0.9 4.1e-07 29.7 0.9 1.6 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.6 RUS91612.1 - 0.0018 18.5 0.3 0.004 17.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) adh_short PF00106.25 RUS91613.1 - 1.2e-49 168.4 0.6 1.6e-49 168.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS91613.1 - 1.5e-34 119.6 0.0 1.9e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS91613.1 - 1.7e-10 41.1 0.4 2.7e-10 40.5 0.4 1.2 1 0 0 1 1 1 1 KR domain ZapA PF05164.13 RUS91613.1 - 0.078 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapA SAM_1 PF00536.30 RUS91613.1 - 0.12 12.9 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Ku_N PF03731.15 RUS91614.1 - 6.4e-26 91.5 0.0 2.1e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 RUS91614.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 RUS91614.1 - 0.012 16.3 0.0 0.05 14.2 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Glutaminase PF04960.15 RUS91616.1 - 9.4e-85 284.2 0.1 1.2e-84 283.9 0.1 1.1 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 RUS91616.1 - 7.2e-08 32.9 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS91616.1 - 7.9e-07 29.2 0.0 4.1e-06 26.9 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91616.1 - 3.7e-06 26.8 0.1 4.6e-05 23.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 RUS91616.1 - 5.2e-06 26.9 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RUS91616.1 - 4.5e-05 23.7 0.0 0.00023 21.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat TFIIS_C PF01096.18 RUS91617.1 - 5e-20 71.1 7.4 5e-20 71.1 7.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RUS91617.1 - 1.3e-07 31.4 0.9 1.3e-07 31.4 0.9 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 RUS91617.1 - 0.0043 16.9 4.6 0.0087 16.0 0.5 2.5 2 0 0 2 2 2 1 Nudix N-terminal Baculo_LEF5_C PF11792.8 RUS91617.1 - 0.013 15.2 1.2 0.035 13.8 1.2 1.8 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 RUS91617.1 - 0.014 15.4 3.6 0.014 15.4 3.6 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 RUS91617.1 - 0.06 12.8 6.9 0.68 9.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 RUS91617.1 - 0.093 12.7 6.4 1.3 9.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C4_Topoisom PF01396.19 RUS91617.1 - 7.5 6.4 11.1 1.1 9.1 0.9 2.5 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger AP3D1 PF06375.11 RUS91618.1 - 0.0033 17.7 2.9 0.0033 17.7 2.9 2.1 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 FAM199X PF15814.5 RUS91618.1 - 0.0038 16.3 1.5 0.0065 15.6 1.5 1.3 1 0 0 1 1 1 1 Protein family FAM199X SprA-related PF12118.8 RUS91618.1 - 0.041 13.0 8.2 0.056 12.6 8.2 1.2 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 RUS91618.1 - 0.37 10.8 9.5 0.85 9.6 9.5 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 RUS91618.1 - 3.1 7.8 10.7 1.1 9.4 5.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3439 PF11921.8 RUS91618.1 - 3.6 7.6 8.6 9.3 6.2 8.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PET117 PF15786.5 RUS91618.1 - 5 7.5 12.7 1.7 9.0 6.2 2.5 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Reprolysin_3 PF13582.6 RUS91619.1 - 1.9e-08 34.9 0.2 1.1e-05 25.9 0.0 4.4 4 1 0 4 4 4 2 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 RUS91619.1 - 2.3e-07 31.2 5.8 0.001 19.5 0.6 2.5 2 0 0 2 2 2 2 ADAM cysteine-rich domain PBP1_TM PF14812.6 RUS91619.1 - 0.024 15.0 0.9 0.024 15.0 0.9 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_peptidase_2 PF04298.12 RUS91619.1 - 0.19 11.1 0.3 9.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase BUD22 PF09073.10 RUS91619.1 - 0.32 10.3 20.1 0.46 9.8 20.1 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 RUS91619.1 - 0.59 9.2 13.2 0.86 8.6 13.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 RUS91619.1 - 2.8 6.4 17.9 4 5.9 17.9 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_7N PF13733.6 RUS91623.1 - 1.5e-43 147.7 0.0 2e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 RUS91623.1 - 1.9e-22 78.7 0.5 3.3e-22 77.9 0.5 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase tRNA_int_endo PF01974.17 RUS91624.1 - 1.4e-20 73.1 0.0 3.1e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MCM PF00493.23 RUS91625.1 - 3.2e-96 320.7 0.1 4.9e-96 320.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RUS91625.1 - 2.3e-32 111.5 0.1 5e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RUS91625.1 - 3.3e-22 78.7 1.6 9.1e-22 77.3 1.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RUS91625.1 - 1.7e-07 30.8 0.0 8.2e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 RUS91625.1 - 4e-05 24.2 0.0 0.00026 21.5 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 RUS91625.1 - 0.0026 17.6 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RUS91625.1 - 0.0084 16.1 0.0 0.037 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RUS91625.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TFIIF_alpha PF05793.12 RUS91625.1 - 0.46 9.0 11.4 0.71 8.4 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 RUS91625.1 - 2.7 8.4 8.3 7 7.1 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Claudin_2 PF13903.6 RUS91626.1 - 7.2e-05 22.6 9.3 0.00036 20.3 9.3 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 RUS91626.1 - 7.8e-05 22.6 6.3 0.002 18.0 0.7 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 RUS91626.1 - 0.00054 19.5 6.1 0.0015 18.1 6.1 1.8 1 1 0 1 1 1 1 Clc-like Claudin_3 PF06653.11 RUS91626.1 - 0.0022 18.0 3.0 0.12 12.3 3.0 2.3 1 1 0 1 1 1 1 Tight junction protein, Claudin-like MARVEL PF01284.23 RUS91626.1 - 0.023 14.7 9.9 0.042 13.9 3.9 2.4 1 1 0 2 2 2 0 Membrane-associating domain SUR7 PF06687.12 RUS91626.1 - 1.8 8.1 5.7 5.3 6.6 5.7 1.9 1 1 0 1 1 1 0 SUR7/PalI family MFS_1 PF07690.16 RUS91629.1 - 1.4e-16 60.4 21.8 1.5e-16 60.3 21.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2523 PF10734.9 RUS91629.1 - 0.1 13.2 8.0 1.5 9.4 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) BT1 PF03092.16 RUS91629.1 - 0.27 9.4 2.9 0.3 9.3 2.9 1.1 1 0 0 1 1 1 0 BT1 family Yippee-Mis18 PF03226.14 RUS91630.1 - 7.3e-07 29.4 0.0 6.3e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.6 RUS91630.1 - 0.023 14.4 3.9 2 8.2 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 RUS91630.1 - 0.11 12.0 2.8 2 7.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 RUS91630.1 - 0.11 12.4 0.8 0.11 12.4 0.8 1.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-tcix PF14952.6 RUS91630.1 - 0.13 11.9 1.0 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 RUS91630.1 - 0.15 11.5 1.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn_ribbon_SprT PF17283.2 RUS91630.1 - 0.2 11.6 3.0 4.7 7.2 0.1 2.6 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 RUS91630.1 - 0.23 11.1 0.8 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 RUS91630.1 - 1.4 9.1 5.1 11 6.2 0.4 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 YhfH PF14149.6 RUS91630.1 - 3.6 7.6 4.8 16 5.5 0.2 3.0 3 0 0 3 3 3 0 YhfH-like protein DUF4772 PF15997.5 RUS91631.1 - 2.6e-25 89.3 0.0 8.2e-25 87.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4772) Tudor_3 PF18115.1 RUS91631.1 - 6.2e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 RUS91631.1 - 7.6e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 RUS91631.1 - 0.0024 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 RUS91631.1 - 0.0056 16.3 0.1 0.027 14.2 0.1 2.2 1 1 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Attacin_N PF03768.15 RUS91631.1 - 0.018 15.2 1.6 0.063 13.4 0.5 2.2 2 0 0 2 2 2 0 Attacin, N-terminal region 53-BP1_Tudor PF09038.10 RUS91631.1 - 0.044 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor FOXP-CC PF16159.5 RUS91631.1 - 0.061 14.0 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 RUS91631.1 - 0.077 13.5 0.2 0.35 11.4 0.2 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type BPL_LplA_LipB PF03099.19 RUS91632.1 - 0.0065 16.4 0.0 0.021 14.7 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SAMP PF05924.11 RUS91632.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 SAMP Motif Ras PF00071.22 RUS91634.1 - 1.1e-40 139.0 0.2 1.4e-40 138.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS91634.1 - 9.2e-24 84.0 0.1 1.5e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS91634.1 - 1e-16 60.9 0.0 1.6e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.31 RUS91634.1 - 4.3e-11 42.8 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1 PF01926.23 RUS91634.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RUS91634.1 - 7.9e-05 22.3 0.1 0.00051 19.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RUS91634.1 - 0.00067 19.1 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region UBA_6 PF18039.1 RUS91634.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain DUF4149 PF13664.6 RUS91635.1 - 2e-21 76.2 13.8 3.6e-21 75.4 7.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) Sulfotransfer_2 PF03567.14 RUS91636.1 - 3.7e-05 23.7 0.5 0.0021 18.0 0.1 2.2 2 0 0 2 2 2 2 Sulfotransferase family DUF4633 PF15464.6 RUS91636.1 - 0.018 15.2 4.5 1.3 9.2 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4633) Sulfotransfer_2 PF03567.14 RUS91637.1 - 2.5e-13 50.5 0.0 4.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family EF-hand_1 PF00036.32 RUS91638.1 - 3.5e-23 79.4 6.3 7.7e-07 28.2 0.7 5.1 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 RUS91638.1 - 2.2e-21 76.1 2.8 7.8e-13 48.7 1.0 3.1 2 1 1 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RUS91638.1 - 1.4e-17 62.0 14.1 3.9e-05 23.2 0.0 5.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 RUS91638.1 - 2.9e-17 62.2 4.3 6.8e-07 29.0 0.1 4.5 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS91638.1 - 3.9e-16 57.7 6.9 2.7e-07 29.7 0.0 4.5 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.6 RUS91638.1 - 3.1e-07 30.6 0.2 0.00095 19.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS91638.1 - 3.6e-05 24.1 3.4 0.00076 19.8 1.0 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Nop14 PF04147.12 RUS91638.1 - 0.00015 20.2 24.4 0.00015 20.1 24.4 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 RUS91638.1 - 0.016 14.6 30.1 0.021 14.3 30.1 1.2 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.9 RUS91638.1 - 0.11 11.5 13.8 0.14 11.0 13.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpoIIIAH PF12685.7 RUS91638.1 - 1 9.1 9.9 1.5 8.6 9.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1126 PF06565.12 RUS91639.1 - 3.7e-102 335.2 1.1 2.6e-34 117.2 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 RUS91639.1 - 1.1e-06 29.0 0.1 2.6e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RUS91639.1 - 0.00023 20.5 0.4 0.019 14.5 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RUS91639.1 - 0.0016 18.2 0.0 0.09 12.8 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain PDZ PF00595.24 RUS91640.1 - 2.2e-05 24.7 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 RUS91640.1 - 0.016 15.7 0.2 0.53 10.8 0.1 2.5 2 0 0 2 2 2 0 PH domain MFS_1 PF07690.16 RUS91641.1 - 9.6e-12 44.5 30.1 9.6e-12 44.5 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PI31_Prot_N PF11566.8 RUS91642.1 - 3.8e-22 78.8 0.1 4.8e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 RUS91642.1 - 3.6e-05 24.9 16.5 3.6e-05 24.9 16.5 2.5 1 1 1 2 2 2 1 PI31 proteasome regulator DUF247 PF03140.15 RUS91642.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function PRKCSH-like PF12999.7 RUS91643.1 - 7.4e-30 104.0 9.8 1.3e-29 103.2 9.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RUS91643.1 - 1.1e-09 38.1 0.1 2.1e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RUS91643.1 - 6.1e-06 27.1 0.0 0.0011 20.0 0.0 3.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 RUS91643.1 - 0.0084 16.3 14.6 0.31 11.3 5.7 2.7 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A RIO1 PF01163.22 RUS91644.1 - 2.1e-62 210.1 0.1 4.8e-62 208.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RUS91644.1 - 0.00013 21.4 0.3 0.0014 18.0 0.3 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RUS91644.1 - 0.0063 15.9 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 RUS91644.1 - 0.011 15.3 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RUS91644.1 - 0.014 14.2 0.0 0.032 13.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RUS91644.1 - 0.019 14.9 0.2 0.058 13.3 0.2 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family AAA_28 PF13521.6 RUS91644.1 - 0.15 12.3 1.6 0.31 11.3 1.6 1.4 1 0 0 1 1 1 0 AAA domain Elongin_A PF06881.11 RUS91645.1 - 8.9e-24 84.0 0.2 8.9e-24 84.0 0.2 4.5 4 1 0 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 RUS91645.1 - 6.3e-07 29.3 0.2 1.9e-06 27.8 0.2 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CBM_14 PF01607.24 RUS91646.1 - 5.7e-11 42.4 0.5 9.5e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 RUS91647.1 - 5.3e-73 246.5 0.0 6.3e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 RUS91647.1 - 0.12 11.7 0.3 4.1 6.6 0.0 2.4 3 0 0 3 3 3 0 Glycoside-hydrolase family GH114 RITA PF17066.5 RUS91649.1 - 7.6e-14 51.9 9.6 2.7e-11 43.6 9.6 2.4 1 1 0 1 1 1 1 RBPJ-interacting and tubulin associated protein Bystin PF05291.11 RUS91650.1 - 8.6e-113 376.4 0.1 1.6e-112 375.6 0.1 1.4 1 0 0 1 1 1 1 Bystin PriC PF07445.12 RUS91650.1 - 0.084 12.8 0.2 0.084 12.8 0.2 2.2 2 0 0 2 2 2 0 Primosomal replication protein priC DUF2624 PF11116.8 RUS91650.1 - 0.11 13.4 0.0 0.5 11.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) STT3 PF02516.14 RUS91651.1 - 1.1e-152 509.4 43.6 1.1e-147 493.0 39.0 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 RUS91651.1 - 0.00084 19.6 13.9 0.00084 19.6 13.9 3.3 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ribosomal_L30_N PF08079.12 RUS91652.1 - 2.5e-28 98.1 18.2 5.7e-28 97.0 18.2 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 RUS91652.1 - 5.6e-22 77.4 0.9 1.6e-21 75.9 0.9 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e F-protein PF00469.20 RUS91652.1 - 0.3 10.7 1.8 17 4.9 1.1 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef AA_permease PF00324.21 RUS91653.1 - 6e-46 157.0 28.1 6e-46 157.0 28.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 RUS91653.1 - 1.3e-19 70.3 28.3 1.3e-19 70.3 28.3 2.1 2 0 0 2 2 2 1 Amino acid permease Zip PF02535.22 RUS91653.1 - 0.011 14.9 0.6 0.011 14.9 0.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Myotub-related PF06602.14 RUS91654.1 - 4.9e-135 450.0 1.1 6.3e-135 449.6 1.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DDE_Tnp_1_7 PF13843.6 RUS91654.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 Hydrolase_6 PF13344.6 RUS91654.1 - 0.036 14.2 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase VWA PF00092.28 RUS91655.1 - 2.2e-11 44.3 0.0 3e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Mito_carr PF00153.27 RUS91657.1 - 4.1e-74 244.6 3.4 3.7e-24 84.5 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein SMC_hinge PF06470.13 RUS91659.1 - 2.4e-10 40.8 0.0 4.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain MscS_porin PF12795.7 RUS91659.1 - 1.7 8.2 12.6 0.14 11.7 3.6 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain LRR_8 PF13855.6 RUS91660.1 - 1.7e-39 133.4 48.5 1.2e-10 41.0 0.7 7.3 5 1 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 RUS91660.1 - 1.6e-25 88.7 36.3 0.00024 21.4 0.3 8.5 3 2 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RUS91660.1 - 7.8e-06 25.7 35.0 7.5 7.5 0.0 12.0 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS91660.1 - 0.0033 17.0 15.6 0.0074 15.8 0.8 3.8 1 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 RUS91660.1 - 1.6 9.0 38.7 1.3 9.2 0.2 10.5 12 0 0 12 12 12 0 Leucine Rich repeat Na_Ca_ex PF01699.24 RUS91662.1 - 2.1e-25 89.4 13.3 2.9e-25 89.0 13.3 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF296 PF03479.15 RUS91663.1 - 1.4e-28 99.4 1.0 1.6e-28 99.2 1.0 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain CiPC PF15800.5 RUS91664.1 - 2.4e-12 47.2 4.4 2.4e-12 47.2 4.4 3.4 2 1 1 3 3 3 1 Clock interacting protein circadian Homeodomain PF00046.29 RUS91665.1 - 1.5e-22 79.2 5.6 2.7e-22 78.3 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RUS91665.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain LmjF365940-deam PF14421.6 RUS91666.1 - 0.031 13.9 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases FAD_binding_2 PF00890.24 RUS91666.1 - 0.038 13.1 0.2 0.062 12.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain PHD PF00628.29 RUS91667.1 - 4.4e-15 55.3 22.5 7e-08 32.2 9.9 2.6 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 RUS91667.1 - 0.0014 18.2 11.2 0.008 15.7 1.3 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 RUS91667.1 - 0.0018 18.1 16.2 0.047 13.6 2.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ETRAMP PF09716.10 RUS91667.1 - 0.0065 16.5 0.3 0.029 14.4 0.3 2.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Prok-RING_1 PF14446.6 RUS91667.1 - 0.0085 16.0 14.7 0.029 14.3 1.6 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Requiem_N PF14051.6 RUS91667.1 - 0.1 12.8 1.0 0.45 10.8 0.6 2.3 1 1 1 2 2 2 0 N-terminal domain of DPF2/REQ. zf-RING_9 PF13901.6 RUS91667.1 - 0.22 11.5 21.1 3.5 7.6 9.4 2.7 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 RUS91667.1 - 0.59 10.3 21.6 0.25 11.5 11.9 3.6 1 1 1 2 2 2 0 PHD-finger ABC_membrane PF00664.23 RUS91668.1 - 3.8e-38 131.7 4.4 5.4e-38 131.2 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS91668.1 - 1.1e-35 123.1 0.0 2.3e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS91668.1 - 4.9e-07 29.4 0.4 9.7e-06 25.2 0.1 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS91668.1 - 0.00011 22.5 0.1 0.00049 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 RUS91668.1 - 0.0002 20.3 0.1 0.00031 19.7 0.1 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 RUS91668.1 - 0.00032 21.1 0.1 0.00096 19.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RUS91668.1 - 0.0086 15.8 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 RUS91668.1 - 0.011 15.7 0.0 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 RUS91668.1 - 0.013 15.8 0.1 1.2 9.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 RUS91668.1 - 0.021 14.8 0.0 0.16 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 RUS91668.1 - 0.044 14.0 0.7 0.53 10.6 0.6 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 RUS91668.1 - 0.069 13.6 0.6 2.6 8.4 0.6 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2057 PF09829.9 RUS91668.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) G-alpha PF00503.20 RUS91668.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit NMT1_2 PF13379.6 RUS91668.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.6 1 1 0 1 1 1 0 NMT1-like family AAA_29 PF13555.6 RUS91668.1 - 0.14 11.9 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 RUS91668.1 - 0.15 12.1 0.3 0.76 9.8 0.0 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain ABC_membrane PF00664.23 RUS91669.1 - 5.5e-103 344.4 26.6 1.5e-60 205.2 4.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS91669.1 - 8.2e-75 249.8 0.1 1.6e-36 125.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS91669.1 - 6.7e-17 61.7 0.0 1.9e-06 27.5 0.0 3.8 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS91669.1 - 4.7e-09 36.6 0.6 0.002 18.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RUS91669.1 - 6.3e-09 36.4 1.9 0.0015 19.0 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 RUS91669.1 - 1.3e-08 34.1 1.0 0.00019 20.4 0.1 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 RUS91669.1 - 3.7e-07 30.2 0.0 0.0046 16.9 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase Rad17 PF03215.15 RUS91669.1 - 1.4e-06 28.3 0.1 0.058 13.3 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA PF00004.29 RUS91669.1 - 3.1e-06 27.6 0.8 0.066 13.6 0.0 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 RUS91669.1 - 1.1e-05 24.7 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 RUS91669.1 - 1.4e-05 25.1 0.3 0.25 11.3 0.0 3.6 3 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 RUS91669.1 - 1.5e-05 24.6 0.2 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 RUS91669.1 - 2.4e-05 23.9 0.0 0.12 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 RUS91669.1 - 2.9e-05 24.2 6.1 0.075 13.3 0.2 4.5 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 RUS91669.1 - 3.9e-05 23.4 0.7 0.69 9.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RUS91669.1 - 7.5e-05 22.1 0.0 0.033 13.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ATP-synt_ab PF00006.25 RUS91669.1 - 0.00033 20.4 0.1 0.097 12.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 RUS91669.1 - 0.00049 19.9 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 RUS91669.1 - 0.00063 20.0 0.1 8.5 6.6 0.0 3.6 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 RUS91669.1 - 0.0011 19.2 0.1 3 7.9 0.0 3.0 4 0 0 4 4 3 2 Helicase HerA, central domain AAA_25 PF13481.6 RUS91669.1 - 0.0016 18.0 0.6 0.21 11.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 RUS91669.1 - 0.0019 17.4 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 RUS91669.1 - 0.0019 18.5 0.0 2.8 8.4 0.0 2.9 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 RUS91669.1 - 0.0025 17.8 0.3 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 RUS91669.1 - 0.0027 17.4 0.0 1.5 8.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 RUS91669.1 - 0.0036 17.1 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 RUS91669.1 - 0.0069 16.2 0.0 4.4 7.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 RUS91669.1 - 0.009 15.2 0.1 4.7 6.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 RUS91669.1 - 0.014 15.2 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase tRNA_lig_kinase PF08303.11 RUS91669.1 - 0.023 14.8 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2057 PF09829.9 RUS91669.1 - 0.023 14.8 0.3 0.47 10.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) AAA_18 PF13238.6 RUS91669.1 - 0.024 15.2 0.0 1.7 9.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 RUS91669.1 - 0.048 13.7 0.3 6 7.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase TniB PF05621.11 RUS91669.1 - 0.058 12.8 0.0 23 4.3 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 RUS91669.1 - 0.075 13.2 0.2 11 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 RUS91669.1 - 0.16 12.5 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2594 PF10769.9 RUS91669.1 - 0.26 11.4 1.4 8.1 6.6 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2594) Wzy_C PF04932.15 RUS91669.1 - 1 9.0 12.0 2.8 7.6 0.2 3.2 3 0 0 3 3 3 0 O-Antigen ligase Ion_trans_N PF08412.10 RUS91670.1 - 3.4e-23 81.0 0.5 6.7e-23 80.0 0.5 1.5 1 0 0 1 1 1 1 Ion transport protein N-terminal DUF5082 PF16888.5 RUS91671.1 - 0.01 16.1 12.6 0.01 16.1 12.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Lzipper-MIP1 PF14389.6 RUS91671.1 - 0.038 14.3 2.2 0.038 14.3 2.2 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.12 RUS91671.1 - 0.055 13.5 13.3 0.074 13.1 5.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RUS91671.1 - 0.066 13.2 22.9 0.022 14.8 18.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vac_Fusion PF02346.16 RUS91671.1 - 0.071 12.7 2.8 0.13 11.9 1.0 2.2 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF948 PF06103.11 RUS91671.1 - 0.098 12.9 0.1 0.098 12.9 0.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) O-antigen_lig PF13425.6 RUS91671.1 - 0.11 11.3 1.6 0.15 10.8 1.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GAS PF13851.6 RUS91671.1 - 0.41 10.0 29.4 3.2 7.1 8.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 RUS91671.1 - 0.48 10.8 21.7 0.56 10.5 8.4 3.6 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 RUS91671.1 - 0.67 10.0 24.0 0.87 9.6 7.5 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 RUS91671.1 - 0.83 9.8 23.5 2.4 8.3 14.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.11 RUS91671.1 - 1.9 7.3 29.5 0.41 9.4 26.2 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 RUS91671.1 - 1.9 8.9 27.9 1.1 9.7 16.9 2.2 1 1 1 2 2 2 0 Fez1 Tox-ODYAM1 PF15642.6 RUS91671.1 - 2 7.3 12.1 2.8 6.8 12.1 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Nup54 PF13874.6 RUS91671.1 - 2.3 8.3 21.8 2.7 8.1 8.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4200 PF13863.6 RUS91671.1 - 2.4 8.6 28.1 0.1 13.0 19.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Golgin_A5 PF09787.9 RUS91671.1 - 2.7 7.4 28.2 0.23 10.9 22.2 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4472 PF14739.6 RUS91671.1 - 2.8 8.7 26.8 1.2 9.9 12.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 RUS91671.1 - 2.8 6.7 29.7 0.19 10.6 11.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 RUS91671.1 - 3.2 7.9 30.4 24 5.1 9.9 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 RUS91671.1 - 4.5 7.7 17.0 4.2 7.8 0.3 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 RUS91671.1 - 8.1 6.5 21.4 4.3 7.4 16.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Kelch_1 PF01344.25 RUS91672.1 - 2.7e-40 135.7 6.2 2.6e-10 39.7 0.0 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 RUS91672.1 - 7.3e-30 102.3 6.3 5.1e-06 26.6 0.0 5.9 4 2 2 6 6 6 5 Kelch motif BTB PF00651.31 RUS91672.1 - 1.1e-26 93.3 0.1 8e-26 90.5 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 RUS91672.1 - 6.5e-23 80.5 1.6 6.1e-05 23.2 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 RUS91672.1 - 1e-21 76.6 1.4 2.1e-06 27.6 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS91672.1 - 4.5e-19 67.6 2.5 0.0017 18.2 0.0 7.2 6 1 0 6 6 6 4 Kelch motif BACK PF07707.15 RUS91672.1 - 2.9e-17 62.6 1.2 5.7e-17 61.7 1.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 RUS91672.1 - 7.4e-09 35.4 9.3 0.19 11.8 0.2 5.3 5 0 0 5 5 5 4 Kelch motif ABC_membrane PF00664.23 RUS91673.1 - 2.8e-67 227.3 8.7 6.7e-67 226.0 8.2 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 RUS91673.1 - 6.3e-35 120.7 0.0 1.4e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RUS91673.1 - 3.8e-06 26.5 0.1 0.0057 16.1 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RUS91673.1 - 0.00033 20.9 0.4 0.0069 16.7 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RUS91673.1 - 0.0017 18.0 0.1 0.0042 16.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RUS91673.1 - 0.0024 18.3 0.1 0.011 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 RUS91673.1 - 0.004 16.0 0.1 1.1 8.0 0.0 2.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 RUS91673.1 - 0.005 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.6 RUS91673.1 - 0.0072 16.2 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 RUS91673.1 - 0.02 14.5 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RUS91673.1 - 0.029 14.5 0.0 0.083 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 RUS91673.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_30 PF13604.6 RUS91673.1 - 0.073 12.8 0.1 1.4 8.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 RUS91673.1 - 0.087 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase RNA_POL_M_15KD PF02150.16 RUS91675.1 - 2.9e-15 55.8 4.8 2.9e-15 55.8 4.8 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 RUS91675.1 - 5.8e-12 45.2 14.6 1.8e-11 43.7 5.6 3.1 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 RUS91675.1 - 6.9e-05 23.3 8.4 0.0014 19.1 0.7 2.1 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain DZR PF12773.7 RUS91675.1 - 0.0037 17.2 2.0 0.0037 17.2 2.0 2.5 2 1 0 2 2 2 1 Double zinc ribbon Ogr_Delta PF04606.12 RUS91675.1 - 0.017 15.1 4.7 0.017 15.1 4.7 2.6 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF3716 PF12511.8 RUS91675.1 - 0.03 14.4 6.5 0.57 10.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) CpXC PF14353.6 RUS91675.1 - 0.049 13.7 9.2 0.74 9.9 0.5 2.3 1 1 1 2 2 2 0 CpXC protein zf-C4_Topoisom PF01396.19 RUS91675.1 - 0.32 10.8 7.8 0.68 9.8 1.4 2.6 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-IS66 PF13005.7 RUS91675.1 - 0.57 10.6 5.7 17 5.9 0.3 3.3 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_Tnp_IS1595 PF12760.7 RUS91675.1 - 8.8 6.4 14.4 0.29 11.1 2.3 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain UPF0242 PF06785.11 RUS91676.1 - 0.00051 20.2 14.1 0.00051 20.2 14.1 8.6 3 3 5 8 8 8 1 Uncharacterised protein family (UPF0242) N-terminus DMPK_coil PF08826.10 RUS91676.1 - 0.0011 19.1 7.2 0.0011 19.1 7.2 10.3 8 4 6 14 14 14 1 DMPK coiled coil domain like Tropomyosin_1 PF12718.7 RUS91676.1 - 0.0079 16.4 24.0 0.0079 16.4 24.0 9.4 4 3 4 8 8 8 2 Tropomyosin like Filament PF00038.21 RUS91676.1 - 0.0088 15.7 13.0 0.0088 15.7 13.0 7.9 4 2 3 7 7 7 4 Intermediate filament protein UL41A PF17591.2 RUS91676.1 - 0.13 12.3 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A HAD_2 PF13419.6 RUS91677.1 - 2.2e-07 31.2 0.2 1.3e-06 28.7 0.0 2.1 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RUS91677.1 - 0.0063 16.8 0.0 0.0083 16.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GPCR_chapero_1 PF11904.8 RUS91677.1 - 0.034 13.6 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 GPCR-chaperone G6PD_N PF00479.22 RUS91677.1 - 0.13 12.9 0.1 1.6 9.3 0.0 2.1 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain MADF_DNA_bdg PF10545.9 RUS91677.1 - 0.3 11.4 2.5 1.6 9.1 0.2 2.6 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RNA_pol_3_Rpc31 PF11705.8 RUS91677.1 - 0.75 10.0 13.4 1.3 9.2 13.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TPR_12 PF13424.6 RUS91678.1 - 3.8e-70 232.2 21.2 1e-20 73.8 2.2 5.4 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 RUS91678.1 - 4.6e-61 201.2 8.0 1.6e-15 56.4 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 RUS91678.1 - 2.1e-32 108.7 10.7 5.4e-06 26.1 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 RUS91678.1 - 3.3e-28 96.3 28.6 1.8e-07 30.7 0.5 6.6 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RUS91678.1 - 4.2e-20 70.2 25.6 0.00013 21.8 2.4 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91678.1 - 3.3e-15 55.0 20.2 0.0019 18.3 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS91678.1 - 1.7e-11 44.6 7.1 0.032 14.9 0.1 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 RUS91678.1 - 2.7e-11 43.4 5.7 3.4e-11 43.1 1.1 2.9 3 1 0 3 3 2 1 MalT-like TPR region TPR_14 PF13428.6 RUS91678.1 - 3.3e-11 43.0 8.2 1.2 10.1 0.0 6.9 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS91678.1 - 4.8e-10 39.1 5.4 0.38 11.2 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS91678.1 - 7e-10 39.3 7.4 0.0016 18.9 0.3 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 RUS91678.1 - 4.6e-07 29.8 0.0 16 6.5 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 RUS91678.1 - 7.4e-07 28.9 0.2 7.4e-07 28.9 0.2 1.7 2 0 0 2 2 1 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 RUS91678.1 - 2.1e-06 27.8 8.4 0.12 12.6 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 RUS91678.1 - 0.002 18.2 7.6 0.12 12.7 0.0 5.3 7 0 0 7 7 5 1 PPR repeat Wzy_C_2 PF11846.8 RUS91678.1 - 0.014 15.3 1.1 3.4 7.5 0.1 3.6 3 1 0 4 4 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_3 PF07720.12 RUS91678.1 - 0.015 15.2 11.5 0.45 10.5 0.9 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 RUS91678.1 - 0.016 15.2 1.5 4.1 7.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF627) DUF2225 PF09986.9 RUS91678.1 - 0.11 12.2 1.3 1.3 8.7 0.4 2.6 2 1 1 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 RUS91678.1 - 0.41 10.7 10.5 10 6.3 1.1 4.8 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain GAS PF13851.6 RUS91678.1 - 0.44 9.9 14.3 20 4.4 14.5 2.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 RUS91678.1 - 0.8 9.8 9.1 0.34 11.0 3.5 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase NUDE_C PF04880.13 RUS91678.1 - 1.1 9.8 4.8 0.67 10.4 2.0 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region PPR_2 PF13041.6 RUS91678.1 - 1.6 9.0 4.8 13 6.1 0.0 3.9 4 0 0 4 4 3 0 PPR repeat family TMF_TATA_bd PF12325.8 RUS91678.1 - 1.7 8.9 14.9 0.11 12.7 4.8 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 RUS91678.1 - 2.4 8.4 8.7 0.24 11.6 2.6 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 RUS91678.1 - 2.8 8.1 13.1 0.63 10.2 7.4 2.8 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) SOGA PF11365.8 RUS91678.1 - 6.8 7.9 11.6 1.9 9.7 6.5 2.8 2 1 1 3 3 2 0 Protein SOGA TSNAXIP1_N PF15739.5 RUS91678.1 - 7.3 7.0 9.5 1.4 9.3 2.5 2.6 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus ADIP PF11559.8 RUS91678.1 - 8.4 6.5 11.8 38 4.3 11.8 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lectin_C PF00059.21 RUS91679.1 - 1.4e-48 164.1 21.1 5.3e-19 68.9 0.7 4.1 4 0 0 4 4 4 3 Lectin C-type domain Amnionless PF14828.6 RUS91679.1 - 0.00069 18.6 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.11 RUS91679.1 - 0.0043 17.2 3.2 0.0043 17.2 3.2 1.8 2 0 0 2 2 2 1 Podoplanin DUF4690 PF15756.5 RUS91679.1 - 0.022 15.3 1.3 0.062 13.9 0.7 2.0 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Mucin15 PF15672.5 RUS91679.1 - 0.11 12.0 2.9 0.074 12.5 1.2 1.5 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 Sulfatase PF00884.23 RUS91680.1 - 2.1e-58 198.1 0.2 3.5e-58 197.4 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS91680.1 - 2.1e-05 24.3 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 RUS91680.1 - 0.023 15.4 0.0 0.049 14.4 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.17 RUS91680.1 - 0.03 12.9 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 RUS91680.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1501 PF07394.12 RUS91680.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.6 RUS91681.1 - 0.0042 17.8 0.0 0.0057 17.4 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 RUS91681.1 - 0.0093 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function FtsJ PF01728.19 RUS91682.1 - 7.6e-69 231.4 0.1 1e-68 230.9 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 RUS91682.1 - 0.093 12.4 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-H2C2_2 PF13465.6 RUS91683.1 - 1.3e-32 110.8 66.2 5.6e-07 29.7 2.5 10.5 11 0 0 11 11 10 9 Zinc-finger double domain zf-C2H2 PF00096.26 RUS91683.1 - 2.5e-20 71.7 85.3 0.00095 19.5 4.0 11.0 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RUS91683.1 - 5.8e-18 64.0 81.9 0.0012 19.5 1.3 11.3 11 0 0 11 11 11 9 C2H2-type zinc finger zf-Di19 PF05605.12 RUS91683.1 - 7.1e-06 26.2 46.0 0.00068 19.9 3.1 6.3 6 1 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RUS91683.1 - 7.7e-05 22.9 37.6 0.99 9.8 2.9 9.2 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS91683.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 10.2 11 0 0 11 11 10 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS91683.1 - 0.0095 15.7 2.3 0.0095 15.7 2.3 6.6 9 0 0 9 9 9 2 C2H2-type zinc-finger domain ADK_lid PF05191.14 RUS91683.1 - 0.018 15.0 1.7 0.018 15.0 1.7 5.0 6 0 0 6 6 5 0 Adenylate kinase, active site lid FOXP-CC PF16159.5 RUS91683.1 - 0.023 15.3 10.8 0.044 14.4 1.6 4.0 3 0 0 3 3 2 0 FOXP coiled-coil domain DUF678 PF05077.12 RUS91683.1 - 0.034 14.3 2.2 8 6.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) zf-met PF12874.7 RUS91683.1 - 0.066 13.6 39.4 1 9.8 1.1 8.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RUS91683.1 - 0.29 11.5 41.3 0.29 11.4 5.6 5.4 2 1 5 7 7 7 0 C2H2-type zinc ribbon zf_C2H2_13 PF18508.1 RUS91683.1 - 2.9 7.6 6.4 31 4.3 0.6 4.0 3 0 0 3 3 3 0 Zinc finger domain Pkinase PF00069.25 RUS91684.1 - 3.9e-25 88.7 0.0 8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91684.1 - 8.3e-19 67.9 0.0 2.5e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RUS91684.1 - 0.00027 20.0 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RUS91684.1 - 0.015 15.2 1.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RUS91684.1 - 0.02 14.2 0.0 0.11 11.8 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 RUS91684.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2114 PF09887.9 RUS91684.1 - 0.059 11.9 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Vta1_C PF18097.1 RUS91684.1 - 0.34 10.6 1.1 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Vta1 C-terminal domain CN_hydrolase PF00795.22 RUS91686.1 - 2.4e-13 50.0 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 RUS91687.1 - 9e-30 103.6 0.1 1.2e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS91687.1 - 7.5e-22 78.0 0.1 1.1e-21 77.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS91687.1 - 2.3e-08 34.2 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 RUS91687.1 - 0.00014 21.8 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 RUS91687.1 - 0.0028 16.7 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SUZ PF12752.7 RUS91688.1 - 1.2e-16 61.2 0.1 1.2e-16 61.2 0.1 3.2 3 1 1 4 4 4 1 SUZ domain SUZ-C PF12901.7 RUS91688.1 - 0.00035 20.5 1.5 0.00044 20.2 0.1 1.9 2 0 0 2 2 2 1 SUZ-C motif I-set PF07679.16 RUS91690.1 - 1.1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS91690.1 - 9.2e-13 48.6 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 RUS91690.1 - 2.4e-07 31.0 0.0 3.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 RUS91690.1 - 4.9e-07 29.8 0.0 7.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS91690.1 - 6.4e-05 23.1 0.0 0.045 13.9 0.0 2.2 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 RUS91690.1 - 0.0054 16.8 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 RUS91690.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin C1-set domain 7tm_1 PF00001.21 RUS91691.1 - 2.2e-76 256.6 6.5 2.9e-76 256.3 6.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91691.1 - 8.1e-07 28.7 9.5 0.00069 19.1 7.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS91691.1 - 0.017 14.8 9.2 0.013 15.2 4.6 2.2 2 0 0 2 2 2 0 Olfactory receptor Phage_holin_3_6 PF07332.11 RUS91691.1 - 1.9 8.6 0.0 1.9 8.6 0.0 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_1 PF00515.28 RUS91692.1 - 6.5e-48 158.7 23.0 1.4e-06 27.8 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 RUS91692.1 - 1.3e-37 124.9 18.2 0.00041 20.3 0.0 9.5 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91692.1 - 5.6e-25 85.4 23.3 0.00027 20.9 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 RUS91692.1 - 5.8e-22 77.1 18.2 3.8e-08 32.9 0.1 8.0 4 2 4 8 8 8 7 TPR repeat TPR_9 PF13371.6 RUS91692.1 - 1.7e-21 76.1 0.6 4.4e-08 33.2 0.2 4.9 3 2 2 5 5 5 5 Tetratricopeptide repeat RPAP3_C PF13877.6 RUS91692.1 - 1.2e-18 67.4 0.0 4.6e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_12 PF13424.6 RUS91692.1 - 2e-16 60.0 14.6 0.00021 21.5 0.7 6.0 5 2 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 RUS91692.1 - 5.5e-12 46.1 6.9 0.00018 22.1 0.0 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RUS91692.1 - 2.5e-11 43.4 8.5 4.7 8.3 0.0 8.3 5 2 4 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS91692.1 - 5.4e-11 42.8 14.3 0.00033 21.1 2.5 6.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS91692.1 - 6.8e-09 35.5 24.8 0.0017 18.6 0.7 7.0 9 0 0 9 9 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS91692.1 - 2.4e-08 33.4 6.3 0.39 10.8 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS91692.1 - 9.6e-07 28.8 17.1 0.12 12.5 0.5 5.5 5 1 1 6 6 6 4 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RUS91692.1 - 5.1e-05 23.0 8.9 4.2 7.4 0.8 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS91692.1 - 5.2e-05 23.6 14.7 0.64 10.8 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat MIT PF04212.18 RUS91692.1 - 0.0013 18.7 24.5 4 7.6 0.0 6.9 5 1 2 7 7 7 3 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 RUS91692.1 - 0.0048 17.1 24.0 0.31 11.3 6.3 5.6 3 3 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 RUS91692.1 - 1.3 9.4 9.9 0.35 11.2 4.7 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Cullin PF00888.22 RUS91693.1 - 1.6e-168 562.2 15.3 2.2e-168 561.7 15.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RUS91693.1 - 8.1e-28 96.3 1.6 2.5e-27 94.7 1.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF5411 PF17424.2 RUS91693.1 - 0.0045 17.0 0.3 0.013 15.4 0.3 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5411) PH PF00169.29 RUS91694.1 - 1.1e-08 35.6 0.1 2.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 PH domain RA PF00788.23 RUS91694.1 - 4.3e-07 30.5 0.2 9.6e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Prp19 PF08606.11 RUS91694.1 - 0.035 14.1 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like HLH PF00010.26 RUS91695.1 - 5e-15 55.2 2.9 5e-15 55.2 2.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TAF4 PF05236.14 RUS91696.1 - 0.002 17.9 9.6 0.0027 17.5 9.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family NPR3 PF03666.13 RUS91696.1 - 2.5 6.8 14.0 2.9 6.6 14.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 RUS91696.1 - 2.7 6.9 4.0 3.3 6.6 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 RUS91696.1 - 3.3 7.5 12.3 4.4 7.0 12.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 RUS91696.1 - 5.2 5.1 9.9 6.3 4.8 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ESSS PF10183.9 RUS91698.1 - 5.2e-17 62.0 0.0 6.5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CBM_14 PF01607.24 RUS91699.1 - 1.4e-09 38.0 7.7 3.8e-09 36.6 7.7 1.8 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Polysacc_deac_1 PF01522.21 RUS91699.1 - 0.00016 21.6 0.0 0.00095 19.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase MLANA PF14991.6 RUS91700.1 - 0.0044 17.3 0.3 0.012 15.9 0.3 1.7 1 0 0 1 1 1 1 Protein melan-A DUF3948 PF13134.6 RUS91700.1 - 0.08 12.7 1.5 0.15 11.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) EphA2_TM PF14575.6 RUS91700.1 - 0.15 13.0 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 RUS91701.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF2985 PF11204.8 RUS91701.1 - 0.54 10.5 2.9 0.61 10.3 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2985) ADH_N PF08240.12 RUS91702.1 - 8.6e-10 38.5 4.1 4.4e-09 36.2 0.6 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS91702.1 - 9.5e-10 38.6 0.5 9.5e-10 38.6 0.5 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 RUS91702.1 - 0.02 15.1 0.1 0.057 13.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Ifi-6-16 PF06140.13 RUS91702.1 - 2 8.4 9.5 0.085 12.8 2.9 2.0 2 0 0 2 2 2 0 Interferon-induced 6-16 family TTL PF03133.15 RUS91703.1 - 1.1e-53 182.3 0.0 1.8e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 RUS91703.1 - 1.5e-08 34.3 0.0 0.00045 19.6 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 RUS91703.1 - 6.1e-08 32.2 0.1 0.0086 15.4 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 RUS91703.1 - 0.0022 17.6 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RUS91703.1 - 0.016 15.2 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Laminin_EGF PF00053.24 RUS91704.1 - 2.9e-11 43.3 67.2 0.002 18.2 12.3 4.2 1 1 3 4 4 4 4 Laminin EGF domain zf-C4 PF00105.18 RUS91705.1 - 2.9e-31 107.7 12.1 4.9e-31 107.0 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS91705.1 - 8.2e-26 90.9 3.6 1.6e-25 89.9 3.6 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf_Rg PF17915.1 RUS91705.1 - 0.62 9.5 6.8 6.5 6.2 0.7 2.8 3 0 0 3 3 3 0 Reverse gyrase zinc finger BACK PF07707.15 RUS91706.1 - 2.2e-18 66.2 1.7 4.3e-18 65.3 0.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 RUS91706.1 - 9e-14 51.7 0.3 3.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Kelch_1 PF01344.25 RUS91706.1 - 2.8e-12 46.0 17.5 2.2e-05 24.0 0.2 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 RUS91706.1 - 2.1e-11 43.7 5.5 0.051 13.9 0.0 5.8 3 1 2 5 5 5 3 Kelch motif Kelch_3 PF13415.6 RUS91706.1 - 0.0011 19.2 0.2 0.68 10.3 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 RUS91706.1 - 0.0014 18.5 15.1 1.1 9.3 0.1 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 RUS91706.1 - 0.0018 18.2 10.7 1.4 9.0 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 RUS91706.1 - 0.0037 17.2 2.6 0.34 10.9 0.0 3.4 2 1 1 3 3 3 1 Galactose oxidase, central domain PQQ_3 PF13570.6 RUS91706.1 - 0.011 16.2 3.3 34 5.1 0.0 4.9 4 1 1 5 5 5 0 PQQ-like domain Striatin PF08232.12 RUS91708.1 - 0.046 14.3 0.8 0.052 14.2 0.8 1.1 1 0 0 1 1 1 0 Striatin family ATG16 PF08614.11 RUS91709.1 - 4.7e-06 27.0 92.3 0.0046 17.2 28.6 5.2 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 RUS91709.1 - 0.00021 21.4 101.8 0.0042 17.3 14.8 5.4 2 2 4 6 6 6 2 Tropomyosin like ZapB PF06005.12 RUS91709.1 - 0.00065 20.1 4.9 0.00065 20.1 4.9 8.3 2 2 3 6 6 4 2 Cell division protein ZapB DUF5082 PF16888.5 RUS91709.1 - 0.00082 19.6 2.3 0.00082 19.6 2.3 6.3 2 1 5 7 7 6 2 Domain of unknown function (DUF5082) Spc7 PF08317.11 RUS91709.1 - 0.00093 18.2 93.8 0.05 12.5 17.1 4.9 1 1 4 5 5 5 2 Spc7 kinetochore protein DUF3450 PF11932.8 RUS91709.1 - 0.002 17.5 6.9 0.002 17.5 6.9 5.9 1 1 6 7 7 7 3 Protein of unknown function (DUF3450) UPF0242 PF06785.11 RUS91709.1 - 0.0029 17.7 91.0 0.84 9.7 1.1 5.4 1 1 1 3 3 2 1 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 RUS91709.1 - 0.003 17.8 7.9 0.003 17.8 7.9 8.6 2 2 5 7 7 6 3 ABC transporter C-terminal domain DivIC PF04977.15 RUS91709.1 - 0.013 15.3 2.0 0.013 15.3 2.0 10.0 2 1 8 10 10 10 0 Septum formation initiator APG6_N PF17675.1 RUS91709.1 - 0.016 15.7 19.2 0.016 15.7 19.2 7.1 1 1 4 5 5 3 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 RUS91709.1 - 0.017 15.2 19.1 0.017 15.2 19.1 5.6 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KMP11 PF03037.16 RUS91709.1 - 0.024 15.4 3.5 0.024 15.4 3.5 4.7 2 1 1 4 4 4 0 Kinetoplastid membrane protein 11 HMMR_N PF15905.5 RUS91709.1 - 0.05 13.1 96.2 0.36 10.2 34.6 5.6 1 1 6 7 7 7 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 RUS91709.1 - 0.059 12.7 67.8 0.033 13.5 15.4 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 RUS91709.1 - 0.1 12.0 77.4 0.021 14.3 2.1 4.9 2 2 3 5 5 5 0 Domain of unknown function (DUF4618) SH3_19 PF18597.1 RUS91709.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain DUF3584 PF12128.8 RUS91709.1 - 0.26 8.8 81.5 1.4 6.3 20.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 RUS91709.1 - 0.29 11.6 84.4 0.28 11.6 9.4 5.0 1 1 3 4 4 4 0 Fez1 SlyX PF04102.12 RUS91709.1 - 0.4 11.3 64.8 0.066 13.8 1.6 9.1 2 2 6 9 9 9 0 SlyX Filament PF00038.21 RUS91709.1 - 0.75 9.3 80.7 0.32 10.5 5.7 4.1 1 1 1 3 3 3 0 Intermediate filament protein Lebercilin PF15619.6 RUS91709.1 - 0.99 9.0 99.4 2.1 8.0 24.4 5.4 1 1 4 6 6 6 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.20 RUS91709.1 - 1.9 7.8 93.6 0.013 14.9 12.8 5.3 1 1 4 5 5 5 0 Tropomyosin AAA_13 PF13166.6 RUS91709.1 - 3.1 6.3 71.2 2.3 6.7 27.6 3.6 1 1 1 3 3 3 0 AAA domain HOOK PF05622.12 RUS91709.1 - 3.3 5.7 89.2 2 6.5 43.6 3.5 1 1 2 3 3 3 0 HOOK protein KASH_CCD PF14662.6 RUS91709.1 - 3.5 7.4 93.0 0.015 15.1 17.0 4.5 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH DUF16 PF01519.16 RUS91709.1 - 5 7.7 66.4 0.6 10.6 12.0 6.6 1 1 4 5 5 5 0 Protein of unknown function DUF16 Csm1_N PF18504.1 RUS91709.1 - 5.1 7.5 79.2 0.098 13.0 1.3 10.0 4 3 5 9 9 8 0 Csm1 N-terminal domain MAD PF05557.13 RUS91709.1 - 5.2 5.3 91.6 0.61 8.4 48.3 3.1 1 1 2 3 3 3 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 RUS91709.1 - 6.1 6.9 97.9 0.04 14.0 4.3 7.2 1 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein Coq4 PF05019.13 RUS91710.1 - 1.3e-93 312.4 0.0 1.6e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Activator_LAG-3 PF11498.8 RUS91712.1 - 5 6.0 18.8 7 5.5 18.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BIR PF00653.21 RUS91714.1 - 3.2e-33 114.2 10.1 6.2e-21 74.8 0.9 3.0 3 0 0 3 3 2 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 RUS91714.1 - 5.2e-13 48.6 11.7 5.2e-13 48.6 11.7 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS91714.1 - 1.5e-05 24.8 11.7 3.5e-05 23.6 11.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SPX PF03105.19 RUS91714.1 - 0.0024 17.9 27.6 0.0039 17.2 27.6 1.3 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 RUS91714.1 - 0.0025 16.8 24.8 0.0038 16.1 24.8 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain zf-RING_5 PF14634.6 RUS91714.1 - 0.016 15.1 11.0 0.016 15.1 11.0 2.0 3 0 0 3 3 1 0 zinc-RING finger domain Atypical_Card PF18461.1 RUS91714.1 - 0.028 14.6 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Atypical caspase recruitment domain DUF2303 PF10065.9 RUS91714.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Smg8_Smg9 PF10220.9 RUS91714.1 - 0.2 9.9 7.7 0.29 9.4 7.7 1.4 1 0 0 1 1 1 0 Smg8_Smg9 Utp14 PF04615.13 RUS91714.1 - 0.32 9.5 8.3 0.49 8.9 8.3 1.3 1 0 0 1 1 1 0 Utp14 protein DUF2039 PF10217.9 RUS91714.1 - 0.55 10.6 6.7 1.6 9.1 6.7 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Nop14 PF04147.12 RUS91714.1 - 0.6 8.3 4.0 0.87 7.7 4.0 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RING_UBOX PF13445.6 RUS91714.1 - 0.63 10.1 11.8 0.89 9.6 6.3 2.8 2 0 0 2 2 2 0 RING-type zinc-finger SOG2 PF10428.9 RUS91714.1 - 1.4 8.0 38.3 2.5 7.2 38.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 RUS91714.1 - 4.6 5.9 15.9 8.3 5.1 15.9 1.3 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 RUS91714.1 - 7 6.1 16.5 14 5.2 16.5 1.4 1 0 0 1 1 1 0 PPP4R2 INTS5_C PF14838.6 RUS91715.1 - 1.5e-127 427.1 6.5 4.8e-64 217.2 1.4 2.1 2 0 0 2 2 2 2 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 RUS91715.1 - 3.8e-68 229.2 0.2 2.2e-65 220.2 0.1 2.7 2 0 0 2 2 2 2 Integrator complex subunit 5 N-terminus WD40 PF00400.32 RUS91716.1 - 2e-22 79.0 6.5 0.0066 17.3 0.0 7.9 8 0 0 8 8 7 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 RUS91716.1 - 5.7e-14 51.7 9.1 1.4e-13 50.4 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS91716.1 - 1.3e-09 37.7 10.5 4.1e-09 36.2 10.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RUS91716.1 - 1.9e-09 37.2 6.9 1.9e-09 37.2 6.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS91716.1 - 5.6e-09 35.9 7.0 5.6e-09 35.9 7.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger ANAPC4_WD40 PF12894.7 RUS91716.1 - 6.3e-09 36.0 0.1 0.079 13.3 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 RUS91716.1 - 1.8e-08 34.6 9.3 6.2e-08 32.8 9.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RUS91716.1 - 3.9e-08 33.1 8.9 3.9e-08 33.1 8.9 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RUS91716.1 - 4.9e-06 26.6 8.9 4.9e-06 26.6 8.9 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING WD40_like PF17005.5 RUS91716.1 - 6e-05 22.5 0.0 0.00035 20.0 0.0 2.1 2 1 1 3 3 3 1 WD40-like domain zf-rbx1 PF12678.7 RUS91716.1 - 0.0021 18.3 8.6 0.0021 18.3 8.6 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 RUS91716.1 - 0.0043 17.2 2.3 0.013 15.6 2.3 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 RUS91716.1 - 0.0052 16.5 7.5 0.017 14.9 7.5 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain ERM PF00769.19 RUS91716.1 - 0.023 14.5 4.8 0.037 13.9 4.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family U-box PF04564.15 RUS91716.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.6 RUS91716.1 - 0.05 13.5 9.8 0.31 10.9 9.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Peptidase_C101 PF16218.5 RUS91716.1 - 0.083 12.1 1.1 0.15 11.3 1.1 1.3 1 0 0 1 1 1 0 Peptidase family C101 zinc-ribbons_6 PF07191.12 RUS91716.1 - 0.15 12.0 4.4 0.51 10.4 4.4 1.9 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 RUS91716.1 - 0.27 11.3 5.1 0.8 9.8 5.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 RUS91716.1 - 0.59 10.0 5.2 1.5 8.7 5.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 RUS91716.1 - 1.3 8.7 6.2 5.5 6.7 6.2 2.1 1 1 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 RUS91716.1 - 3 7.9 6.6 2.1 8.4 2.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 RUS91716.1 - 5.1 7.0 10.3 0.39 10.6 4.3 2.2 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Mesd PF10185.9 RUS91718.1 - 3.6e-71 238.1 3.7 3.6e-71 238.1 3.7 1.5 2 0 0 2 2 2 1 Chaperone for wingless signalling and trafficking of LDL receptor DinB PF05163.12 RUS91718.1 - 0.00074 19.5 0.1 0.0012 18.8 0.1 1.3 1 0 0 1 1 1 1 DinB family zf-C2H2 PF00096.26 RUS91719.1 - 1.6e-30 103.8 150.3 1.4e-05 25.3 0.3 15.2 15 0 0 15 15 15 11 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS91719.1 - 1.2e-29 101.4 128.5 8.3e-05 22.8 4.5 15.7 15 1 0 15 15 15 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS91719.1 - 9.1e-24 82.1 140.9 0.0037 18.0 3.8 15.2 15 0 0 15 15 15 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS91719.1 - 1.4e-10 40.7 138.1 1.6e-07 30.9 1.1 15.5 15 0 0 15 15 15 7 C2H2-type zinc-finger domain SMN PF06003.12 RUS91719.1 - 0.023 13.9 1.6 0.041 13.2 1.6 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-C2H2_8 PF15909.5 RUS91719.1 - 0.03 14.6 3.3 0.03 14.6 3.3 6.7 1 1 6 7 7 7 0 C2H2-type zinc ribbon zf-met PF12874.7 RUS91719.1 - 0.17 12.3 0.2 0.17 12.3 0.2 15.0 15 1 1 16 16 16 0 Zinc-finger of C2H2 type P16-Arc PF04699.14 RUS91720.1 - 1.2e-49 168.6 0.0 1.3e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp13 PF08625.11 RUS91720.1 - 0.02 14.8 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain UTP15_C PF09384.10 RUS91720.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal LRR_9 PF14580.6 RUS91721.1 - 3.4e-11 43.0 3.0 1.7e-08 34.1 0.0 2.9 1 1 1 2 2 2 2 Leucine-rich repeat KASH_CCD PF14662.6 RUS91721.1 - 0.00013 21.8 18.8 0.00013 21.8 18.8 13.7 6 2 8 14 14 14 1 Coiled-coil region of CCDC155 or KASH LRR_4 PF12799.7 RUS91721.1 - 0.0039 17.6 5.3 0.13 12.7 0.4 3.3 1 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Mucin PF01456.17 RUS91721.1 - 0.025 14.6 35.6 0.075 13.0 35.6 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein AvrM_N PF18247.1 RUS91721.1 - 0.048 13.6 0.4 0.39 10.7 0.4 2.8 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain LRR_8 PF13855.6 RUS91721.1 - 0.93 9.3 6.0 0.31 10.8 1.3 2.6 3 0 0 3 3 3 0 Leucine rich repeat RVT_1 PF00078.27 RUS91721.1 - 1.3 8.5 4.6 0.86 9.1 0.0 2.8 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) AJAP1_PANP_C PF15298.6 RUS91721.1 - 9.4 6.4 19.7 38 4.4 19.7 2.0 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DNA_methylase PF00145.17 RUS91723.1 - 4.5e-52 177.5 0.0 4.7e-51 174.1 0.0 2.3 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 RUS91723.1 - 1.5e-41 141.8 0.0 3.6e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 RUS91723.1 - 2.9e-37 127.3 1.0 1.1e-18 67.3 0.0 3.5 3 0 0 3 3 3 2 BAH domain DMAP_binding PF06464.11 RUS91723.1 - 6.3e-10 39.9 0.0 6.3e-10 39.9 0.0 3.0 3 0 0 3 3 3 1 DMAP1-binding Domain ECSCR PF15820.5 RUS91724.1 - 9.4e-06 25.4 0.9 9.4e-06 25.4 0.9 1.8 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator Tmemb_9 PF05434.11 RUS91724.1 - 0.00046 20.1 2.6 0.00046 20.1 2.6 2.0 2 0 0 2 2 2 1 TMEM9 DUF2207 PF09972.9 RUS91724.1 - 0.016 14.0 1.4 0.022 13.5 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 RUS91724.1 - 0.021 15.1 6.6 0.06 13.7 4.1 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF4389 PF14333.6 RUS91724.1 - 0.022 14.7 0.4 0.022 14.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF4834 PF16118.5 RUS91724.1 - 0.051 14.5 5.0 0.25 12.3 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2852 PF11014.8 RUS91724.1 - 0.43 10.7 1.6 1.7 8.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) EphA2_TM PF14575.6 RUS91724.1 - 0.45 11.4 11.0 13 6.7 10.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RUS91724.1 - 0.63 10.2 10.0 0.1 12.8 6.0 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator S_4TM PF18159.1 RUS91724.1 - 1.3 8.2 6.3 0.13 11.6 1.6 1.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Sigma_reg_N PF13800.6 RUS91724.1 - 1.4 9.2 12.4 0.35 11.2 6.6 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TcpE PF12648.7 RUS91724.1 - 1.8 9.2 12.0 0.26 11.9 3.8 2.2 2 0 0 2 2 2 0 TcpE family HemY_N PF07219.13 RUS91724.1 - 2.9 8.1 4.7 1.4 9.2 0.8 2.1 2 0 0 2 2 2 0 HemY protein N-terminus RIFIN PF02009.16 RUS91724.1 - 4.7 7.0 7.9 7 6.4 7.5 1.5 2 0 0 2 2 2 0 Rifin TRP PF06011.12 RUS91724.1 - 6 5.5 11.9 0.3 9.8 6.6 1.4 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel DUF805 PF05656.14 RUS91724.1 - 6.6 7.2 7.4 9.2 6.7 6.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-C4 PF00105.18 RUS91725.1 - 3.6e-29 101.0 12.8 4.2e-29 100.8 11.5 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 RUS91725.1 - 1.8e-28 99.5 1.9 4.4e-28 98.3 1.9 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RIFIN PF02009.16 RUS91725.1 - 0.18 11.6 2.7 0.35 10.7 2.7 1.3 1 0 0 1 1 1 0 Rifin zf-RRPl_C4 PF17026.5 RUS91725.1 - 0.21 11.7 5.9 0.43 10.7 5.9 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Opy2 PF09463.10 RUS91725.1 - 7.8 6.9 7.1 16 6.0 2.0 2.5 2 0 0 2 2 2 0 Opy2 protein RNase_T PF00929.24 RUS91726.1 - 1.7e-07 31.9 0.0 4.3e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 RUS91726.1 - 0.00046 20.2 0.0 0.028 14.4 0.0 2.5 3 0 0 3 3 3 2 RNase_H superfamily Kringle PF00051.18 RUS91727.1 - 2.7e-07 30.8 3.7 2.7e-07 30.8 3.7 1.9 2 0 0 2 2 2 1 Kringle domain SpoVG PF04026.12 RUS91727.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 SpoVG EGF PF00008.27 RUS91728.1 - 1.8e-152 494.9 432.9 1e-08 35.3 9.9 29.6 30 0 0 30 30 29 27 EGF-like domain hEGF PF12661.7 RUS91728.1 - 3.2e-96 313.0 357.2 7.8e-08 32.7 4.7 31.3 31 0 0 31 31 29 27 Human growth factor-like EGF EGF_CA PF07645.15 RUS91728.1 - 9.8e-42 140.9 433.3 6.2e-09 35.9 11.5 28.5 14 8 14 28 28 27 18 Calcium-binding EGF domain Ank_2 PF12796.7 RUS91728.1 - 5.6e-30 103.8 3.4 7.6e-12 45.7 0.4 4.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RUS91728.1 - 8.3e-26 89.3 8.2 0.0004 20.7 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 RUS91728.1 - 3.8e-25 87.6 11.7 1e-09 38.4 0.2 5.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Notch PF00066.17 RUS91728.1 - 9.7e-22 77.1 53.3 4.9e-11 42.9 13.1 16.8 18 7 1 19 19 3 3 LNR domain Ank_3 PF13606.6 RUS91728.1 - 2.3e-20 70.5 2.1 0.00036 20.7 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 RUS91728.1 - 5.1e-18 65.2 1.1 3.2e-06 27.6 0.0 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) NOD PF06816.13 RUS91728.1 - 5.3e-16 58.0 0.0 1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 NOTCH protein EGF_2 PF07974.13 RUS91728.1 - 1.1e-13 51.2 511.7 0.003 17.9 11.4 30.7 31 0 0 31 31 29 19 EGF-like domain NODP PF07684.12 RUS91728.1 - 5.3e-11 42.5 0.2 6e-10 39.1 0.2 3.0 1 0 0 1 1 1 1 NOTCH protein cEGF PF12662.7 RUS91728.1 - 0.00012 22.0 14.0 0.0002 21.2 1.7 27.5 27 1 0 27 27 27 11 Complement Clr-like EGF-like EGF_3 PF12947.7 RUS91728.1 - 0.00033 20.8 8.4 0.00033 20.8 8.4 29.0 21 7 7 28 28 26 15 EGF domain EGF PF00008.27 RUS91730.1 - 6.6e-10 39.1 41.7 2e-05 24.8 10.0 4.1 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 RUS91730.1 - 4.8e-07 29.9 39.4 0.00013 22.1 7.5 3.7 2 2 1 3 3 3 3 Calcium-binding EGF domain hEGF PF12661.7 RUS91730.1 - 6.2e-05 23.5 49.7 0.001 19.6 9.4 4.9 5 0 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 RUS91730.1 - 0.00049 20.4 40.2 0.11 12.9 8.4 4.4 4 1 0 4 4 4 3 EGF-like domain cEGF PF12662.7 RUS91730.1 - 0.026 14.5 2.0 0.026 14.5 2.0 5.3 5 0 0 5 5 5 0 Complement Clr-like EGF-like S4 PF01479.25 RUS91731.1 - 8.4e-10 38.2 0.0 2.3e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 RUS91731.1 - 5.4e-06 27.2 2.9 5.4e-06 27.2 2.9 2.2 2 1 1 3 3 3 1 Ribosomal protein S4/S9 N-terminal domain DUF4404 PF14357.6 RUS91731.1 - 0.076 13.7 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) G-patch PF01585.23 RUS91734.1 - 9.7e-12 44.6 1.3 2e-11 43.6 1.3 1.5 1 0 0 1 1 1 1 G-patch domain zf-CCCH_4 PF18044.1 RUS91734.1 - 0.00046 19.9 2.7 0.00075 19.2 2.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 RUS91734.1 - 0.0075 16.2 1.5 0.014 15.3 1.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tudor_3 PF18115.1 RUS91734.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 RUS91734.1 - 0.025 14.6 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Tudor domain zf_CCCH_4 PF18345.1 RUS91734.1 - 0.063 13.3 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Zinc finger domain Agenet PF05641.12 RUS91734.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.9 1 0 0 1 1 1 0 Agenet domain DUF4602 PF15375.6 RUS91736.1 - 1.6e-12 47.9 7.1 1.6e-12 47.9 7.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4602) PPL5 PF18168.1 RUS91736.1 - 0.12 11.7 4.5 0.17 11.2 4.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF4647 PF15504.6 RUS91738.1 - 9.3e-07 28.3 0.4 2.1e-06 27.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) BAR PF03114.18 RUS91739.1 - 9.7e-54 182.5 10.0 3.2e-47 161.2 2.1 2.3 1 1 1 2 2 2 2 BAR domain SH3_9 PF14604.6 RUS91739.1 - 8.4e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RUS91739.1 - 1.3e-07 31.1 0.1 4.3e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain BAR_3 PF16746.5 RUS91739.1 - 5.6e-06 26.2 2.3 0.0038 17.0 0.1 2.3 1 1 1 2 2 2 2 BAR domain of APPL family SH3_2 PF07653.17 RUS91739.1 - 9.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 RUS91739.1 - 0.0066 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR_2 PF10455.9 RUS91739.1 - 0.02 14.0 2.8 0.29 10.2 0.1 2.7 2 1 1 3 3 3 0 Bin/amphiphysin/Rvs domain for vesicular trafficking fn3 PF00041.21 RUS91740.1 - 3.8e-28 97.7 2.4 7e-15 55.1 0.1 2.7 2 0 0 2 2 2 2 Fibronectin type III domain DUF2207 PF09972.9 RUS91740.1 - 0.0007 18.5 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2062 PF09835.9 RUS91740.1 - 0.0096 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) TMEM154 PF15102.6 RUS91740.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.5 2 0 0 2 2 2 0 TMEM154 protein family INO80_Ies4 PF08193.11 RUS91740.1 - 0.93 9.4 15.0 0.056 13.4 9.0 1.8 1 1 1 2 2 2 0 INO80 complex subunit Ies4 Pepdidase_M14_N PF18027.1 RUS91741.1 - 2.4e-14 53.6 0.1 9.2e-14 51.7 0.1 2.1 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain 7tm_1 PF00001.21 RUS91745.1 - 6.1e-19 68.4 3.3 3.7e-10 39.6 1.6 2.5 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) CARDB PF07705.11 RUS91745.1 - 0.37 11.1 4.7 0.17 12.2 0.9 2.4 2 0 0 2 2 2 0 CARDB Sulfatase PF00884.23 RUS91746.1 - 5.1e-72 242.9 0.7 6.2e-72 242.6 0.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RUS91746.1 - 0.02 14.5 0.6 0.072 12.7 0.6 1.8 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 RUS91746.1 - 0.022 15.5 0.0 0.062 14.0 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 RUS91746.1 - 0.17 10.9 0.2 0.25 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) 7tm_1 PF00001.21 RUS91747.1 - 2.1e-06 27.3 8.6 4.7e-06 26.1 8.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Srg PF02118.21 RUS91747.1 - 0.00099 18.8 9.2 0.00099 18.8 9.2 2.4 2 1 0 2 2 2 1 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.9 RUS91747.1 - 0.0012 18.5 8.8 0.0012 18.5 8.8 2.6 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3169 PF11368.8 RUS91747.1 - 0.03 13.9 0.4 0.03 13.9 0.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2568 PF10823.8 RUS91747.1 - 0.039 14.2 0.2 0.039 14.2 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2568) Peptidase_M49 PF03571.15 RUS91748.1 - 0.11 10.9 3.3 0.2 10.0 3.3 1.6 1 1 0 1 1 1 0 Peptidase family M49 zf-C2H2_4 PF13894.6 RUS91749.1 - 4.4e-14 52.0 28.2 0.00048 20.7 0.4 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91749.1 - 7.2e-13 48.2 29.0 0.00023 21.4 1.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS91749.1 - 6.9e-10 38.9 25.2 8.1e-05 22.9 3.2 4.8 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RUS91749.1 - 1.1e-06 28.4 31.3 0.0026 17.7 0.4 5.0 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS91749.1 - 6.6e-06 26.3 20.2 0.3 11.4 0.3 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 RUS91749.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.4 2 1 0 2 2 1 1 C2H2 Hakai zinc finger domain zf-BED PF02892.15 RUS91749.1 - 0.062 13.3 18.0 0.54 10.3 0.3 4.1 2 1 1 4 4 4 0 BED zinc finger zf-met PF12874.7 RUS91749.1 - 0.12 12.9 25.6 1.9 9.0 2.5 4.7 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS91749.1 - 0.23 11.8 15.6 2.8 8.3 8.6 3.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 RUS91749.1 - 0.68 10.3 12.3 1.3 9.3 8.7 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-FCS PF06467.14 RUS91749.1 - 0.69 9.9 16.6 7.4 6.6 8.7 3.4 2 2 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF4764 PF15961.5 RUS91749.1 - 0.76 8.4 4.2 0.51 9.0 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) Sprouty PF05210.13 RUS91749.1 - 0.9 9.9 9.4 0.16 12.3 1.5 2.1 2 0 0 2 2 2 0 Sprouty protein (Spry) zf-AN1 PF01428.16 RUS91749.1 - 1.2 9.4 21.6 4.1 7.7 0.2 4.3 3 1 1 4 4 4 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 RUS91749.1 - 2.5 8.8 13.6 3.1 8.5 0.9 3.3 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 RUS91749.1 - 2.7 8.3 17.0 11 6.3 4.1 3.0 1 1 2 3 3 3 0 LIM domain FYDLN_acid PF09538.10 RUS91749.1 - 3.8 8.3 7.1 2.1 9.0 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.7 RUS91749.1 - 5.1 7.2 12.7 1.4 8.9 0.9 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain UBZ_FAAP20 PF15750.5 RUS91749.1 - 9.8 6.2 8.5 15 5.6 1.2 3.4 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-C2H2_4 PF13894.6 RUS91750.1 - 1.2e-08 35.0 7.0 0.00064 20.4 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91750.1 - 4.6e-08 33.1 7.5 0.00034 20.9 0.8 3.0 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RUS91750.1 - 1.1e-06 28.7 11.5 0.0037 17.5 0.9 3.3 3 1 1 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RUS91750.1 - 2.6e-06 27.3 6.0 0.0026 17.7 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RUS91750.1 - 1.6e-05 25.1 8.5 0.013 15.9 0.3 3.3 3 1 1 4 4 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 RUS91750.1 - 0.0019 18.5 3.4 0.16 12.3 0.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 RUS91750.1 - 0.0047 17.2 3.6 0.53 10.6 0.2 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 RUS91750.1 - 0.011 16.4 0.7 0.081 13.6 0.7 2.1 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 RUS91750.1 - 0.017 15.1 9.0 0.35 10.9 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger zf-CHCC PF10276.9 RUS91750.1 - 0.02 14.9 1.3 0.93 9.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2HC_2 PF13913.6 RUS91750.1 - 0.061 13.2 5.9 2.7 8.0 2.2 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.12 RUS91750.1 - 0.068 11.7 2.7 0.4 9.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-met PF12874.7 RUS91750.1 - 0.08 13.4 8.2 0.62 10.5 0.9 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RUS91750.1 - 0.081 13.2 2.2 0.093 13.0 2.2 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF2256 PF10013.9 RUS91750.1 - 0.28 11.4 3.5 4.9 7.4 0.4 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 RUS91750.1 - 0.36 11.0 5.0 1.9 8.7 5.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 RUS91751.1 - 1.2e-09 38.1 8.7 4.5e-07 30.0 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RUS91751.1 - 3.5e-08 33.2 3.2 3.9e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RUS91751.1 - 1.5e-07 31.6 11.7 2.4e-05 24.8 0.9 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger GAGA PF09237.11 RUS91751.1 - 0.0006 19.6 1.2 0.00069 19.4 0.3 1.6 1 1 0 1 1 1 1 GAGA factor zf-C2H2_9 PF16293.5 RUS91751.1 - 0.00072 19.3 1.4 0.44 10.4 0.1 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 RUS91751.1 - 0.0011 18.9 4.1 0.081 13.0 1.4 2.4 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.7 RUS91751.1 - 0.0019 18.5 5.0 0.0057 17.0 0.7 2.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 RUS91751.1 - 0.003 17.8 1.8 0.003 17.8 1.8 1.8 2 1 0 2 2 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RUS91751.1 - 0.0096 16.3 5.9 0.19 12.2 0.4 2.7 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 RUS91751.1 - 0.022 14.7 7.9 0.48 10.4 0.2 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RUS91751.1 - 0.022 15.0 2.9 0.049 13.9 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2321 PF10083.9 RUS91751.1 - 0.051 13.2 0.4 0.066 12.8 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-ribbon_8 PF09723.10 RUS91751.1 - 0.077 13.1 2.8 3.3 7.9 0.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 RUS91751.1 - 0.095 12.6 1.5 0.61 10.1 1.5 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.7 RUS91751.1 - 0.13 12.2 2.8 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-AN1 PF01428.16 RUS91751.1 - 0.16 12.2 2.3 8.5 6.6 0.3 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf_UBZ PF18439.1 RUS91751.1 - 0.19 11.4 1.3 16 5.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-HYPF PF07503.12 RUS91751.1 - 0.28 11.0 7.5 3.8 7.4 4.3 3.2 2 1 0 2 2 2 0 HypF finger zf-met PF12874.7 RUS91751.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.1 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 RUS91751.1 - 0.63 10.1 3.6 1.4 9.0 0.3 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF2225 PF09986.9 RUS91751.1 - 0.67 9.6 2.9 2.7 7.7 2.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) FYVE PF01363.21 RUS91751.1 - 2.7 8.2 8.3 64 3.8 8.6 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf_C2H2_6 PF18450.1 RUS91751.1 - 5 6.9 9.1 0.18 11.5 0.6 2.6 3 0 0 3 3 3 0 Zinc Finger domain zf-C2H2_11 PF16622.5 RUS91751.1 - 10 6.0 8.6 1.1 9.1 3.5 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 RUS91753.1 - 3.1e-09 36.9 9.6 8.1e-05 23.1 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91753.1 - 2.9e-07 30.6 11.1 0.00025 21.3 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-MYST PF17772.1 RUS91753.1 - 0.0054 16.3 4.3 0.19 11.3 0.5 2.3 2 1 0 2 2 2 2 MYST family zinc finger domain zf-H2C2_2 PF13465.6 RUS91753.1 - 0.006 17.0 7.3 0.016 15.6 0.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain DUF629 PF04780.12 RUS91753.1 - 0.031 12.8 3.4 0.87 8.0 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-BED PF02892.15 RUS91753.1 - 0.073 13.1 9.1 0.16 12.0 2.6 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 RUS91753.1 - 2.8 7.8 9.8 2.3 8.0 0.9 2.5 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RUS91753.1 - 3 8.3 12.0 0.61 10.4 1.7 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ubiquitin PF00240.23 RUS91754.1 - 4.6e-10 39.1 0.2 1.3e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 RUS91754.1 - 0.00014 21.6 0.0 0.00046 20.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 RUS91754.1 - 0.0002 21.5 0.0 0.00063 19.9 0.0 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain HRI1 PF16815.5 RUS91754.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein HRI1 MBDa PF16564.5 RUS91755.1 - 9.9e-28 96.1 0.7 2.3e-27 95.0 0.7 1.6 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD_C PF14048.6 RUS91755.1 - 1.4e-26 93.0 2.7 3.1e-26 91.9 2.7 1.6 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.19 RUS91755.1 - 1.9e-23 82.0 0.2 4.6e-18 64.7 0.2 2.3 1 1 0 1 1 1 1 Methyl-CpG binding domain 7tm_1 PF00001.21 RUS91756.1 - 7.2e-15 55.0 7.4 1e-14 54.5 7.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91756.1 - 1.4e-06 27.9 5.5 1.9e-06 27.4 5.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS91756.1 - 0.0034 17.0 4.4 0.0034 17.0 4.4 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx BCLP PF12304.8 RUS91756.1 - 0.097 12.2 7.9 1.3 8.5 0.5 2.3 1 1 1 2 2 2 0 Beta-casein like protein MIP PF00230.20 RUS91757.1 - 1e-50 172.6 4.5 1.2e-50 172.3 4.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-C2H2_4 PF13894.6 RUS91758.1 - 4.7e-16 58.1 61.9 0.046 14.6 0.9 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91758.1 - 5.5e-11 42.3 63.3 0.02 15.3 1.0 9.1 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS91758.1 - 1.6e-05 25.1 60.1 0.0042 17.5 1.0 9.7 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_3rep PF18868.1 RUS91758.1 - 0.0032 18.1 26.9 0.47 11.1 5.8 6.0 4 2 2 6 6 6 3 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 RUS91758.1 - 0.042 14.1 1.5 4 7.8 0.1 3.7 2 1 1 3 3 3 0 Ta0938 zf-C2HC_2 PF13913.6 RUS91758.1 - 0.22 11.4 0.0 0.22 11.4 0.0 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RUS91758.1 - 0.46 10.8 51.3 0.59 10.5 0.8 8.7 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 RUS91759.1 - 4.2e-29 101.7 0.0 7.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 RUS91759.1 - 4e-08 33.6 8.0 3.4e-06 27.3 0.0 3.7 3 1 1 4 4 4 2 RNase H DUF1657 PF07870.11 RUS91759.1 - 0.061 13.2 0.4 0.25 11.2 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Alpha-mann_mid PF09261.11 RUS91759.1 - 0.29 11.3 0.1 0.29 11.3 0.1 3.2 3 1 0 3 3 3 0 Alpha mannosidase middle domain ThiF PF00899.21 RUS91761.1 - 9.1e-95 316.7 0.0 7.6e-60 202.3 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RUS91761.1 - 9.8e-75 251.7 0.3 1.5e-74 251.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 RUS91761.1 - 2.4e-29 101.3 2.1 5.7e-29 100.1 2.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 RUS91761.1 - 1.2e-16 61.1 0.1 1.7e-15 57.5 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin fold domain E1_4HB PF16191.5 RUS91761.1 - 1.2e-16 60.6 0.2 4.1e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 RUS91761.1 - 0.028 14.5 0.1 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 RUS91761.1 - 0.045 14.2 0.1 0.7 10.4 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF3543 PF12063.8 RUS91761.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Pyr_redox PF00070.27 RUS91761.1 - 0.21 12.2 2.2 13 6.4 0.6 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 RUS91762.1 - 0.077 13.6 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RhoGEF PF00621.20 RUS91763.1 - 1e-32 113.8 5.9 3.1e-32 112.3 5.9 1.9 1 0 0 1 1 1 1 RhoGEF domain PH_16 PF17838.1 RUS91763.1 - 2.3e-29 101.8 0.0 4.8e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 RUS91763.1 - 2.1e-06 27.5 6.6 4.3e-06 26.5 6.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RUS91763.1 - 0.0038 17.7 2.2 0.018 15.6 0.0 2.6 2 0 0 2 2 2 1 PH domain TPR_MLP1_2 PF07926.12 RUS91763.1 - 0.1 12.7 30.3 0.13 12.4 16.7 4.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 RUS91763.1 - 0.54 9.5 16.7 0.2 11.0 7.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2616 PF11077.8 RUS91763.1 - 0.85 9.3 6.6 2.4 7.8 6.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) BRD4_CDT PF17105.5 RUS91763.1 - 1.7 8.3 15.4 2 8.1 0.5 3.1 2 1 0 2 2 2 0 C-terminal domain of bromodomain protein 4 7tm_1 PF00001.21 RUS91764.1 - 2.4e-54 184.4 21.4 2.8e-54 184.2 21.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 RUS91764.1 - 2.4e-10 40.3 14.0 9.3e-10 38.3 11.7 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 RUS91764.1 - 2.4e-05 23.6 12.5 5.9e-05 22.3 12.5 1.7 1 1 0 1 1 1 1 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 RUS91764.1 - 0.0012 18.6 19.2 0.032 14.0 19.2 2.3 1 1 0 1 1 1 1 Olfactory receptor DUF2852 PF11014.8 RUS91764.1 - 3 8.0 6.0 9.1 6.5 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) 7TM_GPCR_Srx PF10328.9 RUS91764.1 - 9.1 5.8 20.4 6.7 6.2 16.8 2.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4541 PF15074.6 RUS91766.1 - 3.7e-10 40.3 0.4 5.5e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Pkinase_Tyr PF07714.17 RUS91767.1 - 4.6e-29 101.5 0.0 1.5e-28 99.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RUS91767.1 - 4.1e-19 69.0 0.0 6.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PBP_like_2 PF12849.7 RUS91768.1 - 1.2e-24 87.5 0.0 1.5e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 RUS91768.1 - 0.00085 18.5 0.0 0.0018 17.4 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain Hydantoinase_B PF02538.14 RUS91769.1 - 2.9e-199 662.8 2.4 4.4e-198 658.9 2.4 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 RUS91769.1 - 2.2e-100 335.7 0.3 4.5e-100 334.7 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 RUS91769.1 - 3.8e-61 205.9 0.2 3.3e-59 199.6 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region COesterase PF00135.28 RUS91770.1 - 6.8e-143 477.2 0.0 8.3e-143 476.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS91770.1 - 8.2e-07 29.1 0.5 2.4e-06 27.6 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold SAGA-Tad1 PF12767.7 RUS91771.1 - 1.9e-20 73.6 2.0 1.2e-10 41.6 0.8 2.2 1 1 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit EF-hand_7 PF13499.6 RUS91772.1 - 6.3e-05 23.3 0.0 0.00039 20.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RUS91772.1 - 0.0027 17.5 0.1 0.0058 16.5 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 RUS91772.1 - 0.0056 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 EF hand 7tm_2 PF00002.24 RUS91773.1 - 2.9e-24 85.7 15.9 4.6e-24 85.1 15.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3160 PF11369.8 RUS91773.1 - 0.11 10.9 0.2 0.16 10.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) 7tm_1 PF00001.21 RUS91774.1 - 3.5e-15 56.0 15.0 1.7e-10 40.7 7.6 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 RUS91774.1 - 4.3e-13 49.2 19.3 1.4e-11 44.2 1.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS91774.1 - 0.00046 19.9 13.5 0.00046 19.9 13.5 2.4 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx NMT_C PF02799.15 RUS91776.1 - 2.2e-05 24.1 10.9 1 8.9 0.6 4.6 1 1 3 4 4 4 4 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NUDIX_5 PF16705.5 RUS91776.1 - 0.0011 18.8 2.9 0.29 10.9 0.6 2.5 1 1 1 2 2 2 2 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Imm_superinfect PF14373.6 RUS91776.1 - 0.0058 16.5 11.1 34 4.5 0.1 5.0 5 0 0 5 5 5 4 Superinfection immunity protein Spike_NTD PF16451.5 RUS91776.1 - 0.05 12.9 6.6 3.1 7.1 0.4 3.0 1 1 3 4 4 4 0 Spike glycoprotein N-terminal domain Ninjurin PF04923.12 RUS91776.1 - 0.092 12.7 0.7 13 5.8 0.0 2.6 1 1 2 3 3 3 0 Ninjurin DUF4148 PF13663.6 RUS91777.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) SSF PF00474.17 RUS91778.1 - 1.8e-34 119.3 22.9 2.4e-34 118.9 22.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Spo7 PF03907.13 RUS91779.1 - 0.06 12.8 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Spo7-like protein Phi-29_GP16_7 PF06720.11 RUS91779.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 CYTH PF01928.21 RUS91780.1 - 3.3e-05 23.9 0.0 9.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 CYTH domain SDA1 PF05285.12 RUS91781.1 - 1.8e-06 27.7 12.9 2.1e-06 27.5 12.9 1.1 1 0 0 1 1 1 1 SDA1 RPN2_C PF18004.1 RUS91781.1 - 0.00017 21.5 11.6 0.00026 20.9 11.6 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 RUS91781.1 - 0.00018 19.9 19.2 0.00021 19.7 19.2 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 RUS91781.1 - 0.0005 19.5 12.0 0.00057 19.3 12.0 1.1 1 0 0 1 1 1 1 BUD22 Eapp_C PF10238.9 RUS91781.1 - 0.00076 19.6 1.2 0.0011 19.1 1.2 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF2052 PF09747.9 RUS91781.1 - 0.00076 19.7 17.5 0.0012 19.0 17.5 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Connexin PF00029.19 RUS91781.1 - 0.0017 18.2 5.9 0.0022 17.8 5.9 1.1 1 0 0 1 1 1 1 Connexin RR_TM4-6 PF06459.12 RUS91781.1 - 0.0024 17.7 16.4 0.0032 17.4 16.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 RUS91781.1 - 0.0026 18.2 5.1 0.0037 17.7 5.1 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 SpoIIP PF07454.11 RUS91781.1 - 0.0026 17.2 7.2 0.0032 17.0 7.2 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Sigma70_ner PF04546.13 RUS91781.1 - 0.0032 17.4 14.3 0.0045 16.9 14.3 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RUS91781.1 - 0.0044 15.2 27.7 0.006 14.8 27.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi MDM1 PF15501.6 RUS91781.1 - 0.0062 15.8 9.9 0.0072 15.5 9.9 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 PTPRCAP PF15713.5 RUS91781.1 - 0.0077 16.5 22.0 0.014 15.7 22.0 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Tim54 PF11711.8 RUS91781.1 - 0.009 14.8 11.5 0.012 14.5 11.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Slu7 PF11708.8 RUS91781.1 - 0.01 15.6 9.9 0.013 15.3 9.9 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF4820 PF16091.5 RUS91781.1 - 0.011 15.1 7.4 0.016 14.6 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 RUS91781.1 - 0.012 15.8 0.5 0.013 15.7 0.5 1.1 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 RUS91781.1 - 0.016 14.2 2.2 0.017 14.1 2.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FYDLN_acid PF09538.10 RUS91781.1 - 0.016 15.8 12.0 0.025 15.3 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 RUS91781.1 - 0.021 15.2 13.7 0.028 14.7 13.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 RUS91781.1 - 0.031 13.3 4.8 0.039 12.9 4.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 RUS91781.1 - 0.037 13.8 15.3 0.053 13.3 15.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SID-1_RNA_chan PF13965.6 RUS91781.1 - 0.041 12.3 0.5 0.05 12.0 0.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.18 RUS91781.1 - 0.05 12.3 1.1 0.061 12.1 1.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier CobT PF06213.12 RUS91781.1 - 0.051 13.0 23.3 0.064 12.6 23.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 RUS91781.1 - 0.062 11.6 19.0 0.079 11.3 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 RUS91781.1 - 0.066 13.4 11.3 0.11 12.6 11.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BSP_II PF05432.11 RUS91781.1 - 0.077 12.7 28.9 0.14 11.8 28.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YABBY PF04690.13 RUS91781.1 - 0.081 13.5 1.0 0.12 12.9 1.0 1.2 1 0 0 1 1 1 0 YABBY protein DUF5523 PF17661.1 RUS91781.1 - 0.087 12.5 22.8 0.11 12.1 22.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2151 PF10221.9 RUS91781.1 - 0.095 11.3 6.5 0.11 11.1 6.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FHIPEP PF00771.20 RUS91781.1 - 0.11 10.9 1.4 0.14 10.6 1.4 1.1 1 0 0 1 1 1 0 FHIPEP family TRAP_alpha PF03896.16 RUS91781.1 - 0.11 11.6 14.4 0.15 11.2 14.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.19 RUS91781.1 - 0.12 10.2 8.0 0.16 9.9 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 RUS91781.1 - 0.12 10.4 5.9 0.15 10.1 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 RUS91781.1 - 0.13 12.3 2.4 0.17 11.8 2.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3391 PF11871.8 RUS91781.1 - 0.13 12.8 9.6 0.19 12.2 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Mpp10 PF04006.12 RUS91781.1 - 0.13 10.6 29.1 0.18 10.2 29.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Mem_trans PF03547.18 RUS91781.1 - 0.14 10.5 1.0 0.19 10.1 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein MRNIP PF15749.5 RUS91781.1 - 0.19 12.4 8.7 0.36 11.6 8.7 1.5 1 0 0 1 1 1 0 MRN-interacting protein GNAT_acetyltr_2 PF13718.6 RUS91781.1 - 0.19 11.1 5.1 0.26 10.7 5.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Dynamin_N PF00350.23 RUS91781.1 - 0.19 11.7 1.6 0.22 11.5 1.6 1.2 1 0 0 1 1 1 0 Dynamin family SMN PF06003.12 RUS91781.1 - 0.22 10.8 2.4 0.29 10.4 2.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GAGA_bind PF06217.12 RUS91781.1 - 0.23 11.7 2.6 0.29 11.4 2.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 RUS91781.1 - 0.23 10.4 4.2 0.28 10.2 4.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Cellulose_synt PF03552.14 RUS91781.1 - 0.25 9.8 3.9 0.31 9.5 3.9 1.1 1 0 0 1 1 1 0 Cellulose synthase OATP PF03137.20 RUS91781.1 - 0.25 9.6 1.0 0.33 9.2 1.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DARPP-32 PF05395.12 RUS91781.1 - 0.26 11.5 21.1 0.4 10.9 21.1 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 PI3K_1B_p101 PF10486.9 RUS91781.1 - 0.28 8.9 9.2 0.33 8.7 9.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EIIBC-GUT_N PF03612.14 RUS91781.1 - 0.3 10.8 8.2 0.52 10.0 8.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus VIR_N PF15912.5 RUS91781.1 - 0.36 10.4 9.3 0.46 10.0 9.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CSG2 PF16965.5 RUS91781.1 - 0.48 9.3 1.8 0.61 9.0 1.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2722 PF10846.8 RUS91781.1 - 0.52 9.2 6.3 0.72 8.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 RUS91781.1 - 0.54 9.0 9.9 0.7 8.6 9.9 1.1 1 0 0 1 1 1 0 Presenilin TLP-20 PF06088.11 RUS91781.1 - 0.6 10.0 9.5 1.1 9.2 9.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3408 PF11888.8 RUS91781.1 - 0.61 10.2 19.0 0.99 9.5 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_S64 PF08192.11 RUS91781.1 - 0.62 8.5 4.3 0.68 8.3 4.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 CLN3 PF02487.17 RUS91781.1 - 0.63 9.0 5.5 0.81 8.7 5.5 1.1 1 0 0 1 1 1 0 CLN3 protein RXT2_N PF08595.11 RUS91781.1 - 0.67 10.0 13.2 1.2 9.1 13.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal AIF_C PF14721.6 RUS91781.1 - 0.85 10.0 8.0 1.4 9.3 8.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3306 PF11748.8 RUS91781.1 - 0.99 10.3 13.1 1.6 9.6 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) O-antigen_lig PF13425.6 RUS91781.1 - 1 8.1 5.3 1.3 7.7 5.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Paf1 PF03985.13 RUS91781.1 - 1.1 8.2 30.9 1.5 7.8 30.9 1.1 1 0 0 1 1 1 0 Paf1 DUF4045 PF13254.6 RUS91781.1 - 1.1 8.8 9.3 1.5 8.4 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CENP-N PF05238.13 RUS91781.1 - 1.2 8.3 5.9 1.5 8.0 5.9 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Sec62 PF03839.16 RUS91781.1 - 1.2 8.6 9.4 1.8 8.0 9.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_11 PF13086.6 RUS91781.1 - 1.2 8.8 8.5 1.6 8.5 8.5 1.1 1 0 0 1 1 1 0 AAA domain PPL5 PF18168.1 RUS91781.1 - 1.3 8.2 6.0 1.7 7.9 6.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Usp PF00582.26 RUS91781.1 - 1.3 9.5 11.3 2.2 8.8 11.3 1.3 1 0 0 1 1 1 0 Universal stress protein family TFB6 PF17110.5 RUS91781.1 - 1.5 8.5 13.4 2.2 8.0 13.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Zip PF02535.22 RUS91781.1 - 1.5 7.9 7.3 2 7.5 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RAB3GAP2_C PF14656.6 RUS91781.1 - 1.6 6.8 9.4 2 6.5 9.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Hid1 PF12722.7 RUS91781.1 - 1.8 6.6 6.9 2.4 6.2 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM10 PF12519.8 RUS91781.1 - 1.8 7.3 5.5 2.2 7.1 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 RUS91781.1 - 1.9 7.2 5.6 2.5 6.8 5.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Serinc PF03348.15 RUS91781.1 - 2.2 7.1 4.0 2.8 6.8 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) HSP70 PF00012.20 RUS91781.1 - 2.5 6.2 17.1 3.3 5.8 17.1 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4746 PF15928.5 RUS91781.1 - 2.6 7.4 25.3 4.4 6.6 25.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) THOC2_N PF16134.5 RUS91781.1 - 2.6 6.5 9.2 3.6 6.1 9.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Ureide_permease PF07168.11 RUS91781.1 - 2.9 6.5 5.5 4.1 6.1 5.5 1.1 1 0 0 1 1 1 0 Ureide permease Nucleoside_tran PF01733.18 RUS91781.1 - 3.1 7.1 3.8 4.6 6.5 3.8 1.3 1 0 0 1 1 1 0 Nucleoside transporter Saw1 PF11561.8 RUS91781.1 - 4.6 6.7 9.2 6.3 6.3 9.2 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 D123 PF07065.14 RUS91781.1 - 5.1 6.2 9.4 7.1 5.7 9.4 1.2 1 0 0 1 1 1 0 D123 HSP90 PF00183.18 RUS91781.1 - 5.1 5.9 29.0 6.8 5.5 29.0 1.1 1 0 0 1 1 1 0 Hsp90 protein TRM13 PF05206.14 RUS91781.1 - 5.2 6.5 7.6 9.2 5.7 7.6 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 TMEM119 PF15724.5 RUS91781.1 - 7.2 6.6 12.0 10 6.1 12.0 1.2 1 0 0 1 1 1 0 TMEM119 family Drc1-Sld2 PF11719.8 RUS91781.1 - 8.1 5.9 20.7 11 5.4 20.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein STAC2_u1 PF16664.5 RUS91781.1 - 8.5 6.8 14.5 14 6.1 14.5 1.3 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 NARP1 PF12569.8 RUS91781.1 - 9.4 5.0 16.4 13 4.6 16.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NOA36 PF06524.12 RUS91781.1 - 9.6 5.4 23.8 17 4.6 23.8 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 RUS91783.1 - 0.034 13.6 13.8 0.042 13.3 13.8 1.1 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.9 RUS91783.1 - 0.036 14.2 13.1 0.048 13.8 13.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Myc_N PF01056.18 RUS91783.1 - 0.046 13.6 7.0 0.058 13.3 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PTPRCAP PF15713.5 RUS91783.1 - 0.047 14.0 14.2 0.069 13.4 14.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PBECR1 PF18809.1 RUS91783.1 - 0.056 14.1 0.3 0.056 14.1 0.3 2.0 2 0 0 2 2 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Nop14 PF04147.12 RUS91783.1 - 0.069 11.4 15.4 0.08 11.1 15.4 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 RUS91783.1 - 0.13 12.6 3.0 0.23 11.8 3.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 RUS91783.1 - 0.2 10.4 0.7 0.2 10.4 0.7 1.1 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 RUS91783.1 - 0.2 10.1 16.0 0.24 9.8 16.0 1.0 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 RUS91783.1 - 0.25 11.1 9.5 0.33 10.7 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 RUS91783.1 - 0.29 11.3 4.3 0.43 10.7 4.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 RUS91783.1 - 0.32 9.1 17.7 0.38 8.8 17.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 RUS91783.1 - 0.33 10.6 23.1 0.44 10.2 23.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 RUS91783.1 - 0.76 8.0 12.5 0.94 7.7 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 RUS91783.1 - 0.85 8.9 13.9 1.2 8.4 13.9 1.2 1 0 0 1 1 1 0 NOA36 protein MscS_TM PF12794.7 RUS91783.1 - 0.86 8.4 1.3 1 8.2 1.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RNA_polI_A34 PF08208.11 RUS91783.1 - 1.1 9.3 11.8 1.6 8.8 11.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.16 RUS91783.1 - 1.1 8.4 7.5 1.5 7.9 7.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 RUS91783.1 - 1.1 8.9 4.5 1.5 8.6 4.5 1.1 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 RUS91783.1 - 1.5 8.5 10.6 2.5 7.7 10.6 1.3 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.14 RUS91783.1 - 1.5 9.2 5.6 2.6 8.5 5.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 RUS91783.1 - 2.6 7.8 12.9 4 7.2 12.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PI3K_1B_p101 PF10486.9 RUS91783.1 - 2.8 5.6 6.4 3.5 5.3 6.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Afi1 PF07792.12 RUS91783.1 - 3.1 8.3 7.3 5 7.6 7.3 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RPN2_C PF18004.1 RUS91783.1 - 3.5 7.5 14.1 5.6 6.9 14.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop53 PF07767.11 RUS91783.1 - 3.6 6.9 19.2 5 6.4 19.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.12 RUS91783.1 - 9.6 4.7 22.2 12 4.3 22.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DREV PF05219.12 RUS91785.1 - 7.3e-89 297.4 0.1 9.1e-89 297.0 0.1 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 RUS91785.1 - 5.2e-13 49.1 0.0 1.3e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RUS91785.1 - 9.2e-08 32.6 0.2 3.3e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS91785.1 - 5.1e-07 30.4 0.0 1.7e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS91785.1 - 4.9e-06 27.2 0.1 2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 RUS91785.1 - 0.0033 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 RUS91785.1 - 0.0037 17.1 0.6 0.16 11.7 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RUS91785.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PPR_1 PF12854.7 RUS91786.1 - 0.0013 18.4 1.7 16 5.3 0.0 5.1 4 2 0 4 4 4 1 PPR repeat HycA_repressor PF11046.8 RUS91786.1 - 0.22 11.7 1.7 20 5.4 0.2 2.6 1 1 0 2 2 2 0 Transcriptional repressor of hyc and hyp operons Sushi PF00084.20 RUS91787.1 - 6.7e-07 29.8 1.1 1.2e-06 29.0 1.1 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) TMEM100 PF16311.5 RUS91787.1 - 0.017 14.7 0.3 0.032 13.8 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4371 PF14291.6 RUS91788.1 - 1.8e-15 57.3 0.0 3.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) DUF659 PF04937.15 RUS91788.1 - 0.00014 21.7 0.1 0.00059 19.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 RUS91788.1 - 0.038 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region LPD29 PF18847.1 RUS91788.1 - 0.15 13.1 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 DUF1786 PF08735.10 RUS91788.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) MAM PF00629.23 RUS91789.1 - 1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ldl_recept_a PF00057.18 RUS91789.1 - 7.5e-09 35.7 8.0 1.2e-08 35.0 8.0 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Reprolysin PF01421.19 RUS91790.1 - 2.7e-27 96.0 0.0 6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 RUS91790.1 - 3.9e-26 91.9 4.3 4.3e-26 91.8 0.2 2.8 3 0 0 3 3 3 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 RUS91790.1 - 7.6e-20 71.2 7.0 7.6e-20 71.2 7.0 2.4 2 0 0 2 2 2 1 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 RUS91790.1 - 1.2e-16 61.5 0.8 1.2e-16 61.5 0.8 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 RUS91790.1 - 1.9e-13 51.0 0.2 3.5e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 RUS91790.1 - 2.4e-10 40.7 0.1 5e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RUS91790.1 - 1.9e-06 27.7 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 RUS91790.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 RUS91790.1 - 0.015 15.2 0.4 0.03 14.2 0.4 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 RUS91790.1 - 0.034 13.1 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 RUS91790.1 - 0.24 11.4 1.3 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M54 Apis_Csd PF11671.8 RUS91790.1 - 4.7 7.2 6.2 7.9 6.5 6.2 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein ADAM_spacer1 PF05986.14 RUS91791.1 - 1.2e-33 115.6 0.0 1.7e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 RUS91791.1 - 5e-24 84.3 88.5 1.1e-05 25.6 3.4 7.3 7 1 0 7 7 7 6 Thrombospondin type 1 domain PLAC PF08686.11 RUS91791.1 - 0.00028 21.6 7.4 0.0022 18.7 7.4 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain ADH_N PF08240.12 RUS91792.1 - 8e-30 102.9 5.3 8e-30 102.9 5.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RUS91792.1 - 4.1e-21 75.3 0.2 1.8e-15 57.1 0.0 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RUS91792.1 - 2.9e-07 30.2 0.1 0.02 14.4 0.1 2.2 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RUS91792.1 - 2.4e-05 25.4 0.0 8.1e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 RUS91792.1 - 0.00089 18.6 0.2 0.0015 17.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 RUS91792.1 - 0.052 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 RUS91792.1 - 0.055 14.0 0.4 1.1 9.9 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RUS91792.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RUS91792.1 - 0.17 11.1 1.7 0.75 9.0 0.4 2.3 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RUS91792.1 - 0.47 9.1 1.5 0.75 8.4 1.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Kelch_1 PF01344.25 RUS91794.1 - 8.8e-73 239.7 16.0 8.8e-14 50.8 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 RUS91794.1 - 5.1e-38 128.1 6.0 3.6e-07 30.2 0.0 6.4 2 1 4 6 6 6 6 Kelch motif BTB PF00651.31 RUS91794.1 - 8e-29 100.1 0.0 1.7e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 RUS91794.1 - 3.9e-27 93.2 4.1 8.3e-07 28.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 RUS91794.1 - 7.8e-26 90.2 0.1 1.4e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 RUS91794.1 - 3.3e-21 75.1 10.4 0.00021 21.5 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 RUS91794.1 - 2.7e-13 49.6 8.4 0.007 16.3 0.4 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 RUS91794.1 - 5.4e-12 45.5 5.7 0.00033 20.6 0.1 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain TGFb_propeptide PF00688.18 RUS91796.1 - 7.7e-14 52.0 0.0 1.9e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 TGF-beta propeptide Pkinase PF00069.25 RUS91797.1 - 5.1e-74 249.0 0.0 5.8e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91797.1 - 2.3e-33 115.6 0.0 2.9e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS91797.1 - 0.00011 21.6 0.1 0.0039 16.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RUS91797.1 - 0.0013 17.8 0.0 0.018 14.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 RUS91797.1 - 0.013 14.5 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RUS91797.1 - 0.016 14.5 0.2 0.035 13.4 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RUS91797.1 - 0.032 14.1 0.1 0.08 12.8 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family SET PF00856.28 RUS91798.1 - 3.7e-13 50.2 0.3 1.9e-12 47.9 0.3 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 RUS91798.1 - 0.00091 19.3 13.2 0.00091 19.3 13.2 2.4 3 0 0 3 3 3 1 MYND finger zf-CCHC PF00098.23 RUS91799.1 - 0.00078 19.4 1.0 0.002 18.1 1.0 1.8 1 0 0 1 1 1 1 Zinc knuckle TUDOR PF00567.24 RUS91800.1 - 6.1e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF966 PF06136.13 RUS91800.1 - 0.48 10.1 8.1 0.64 9.7 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SEP PF08059.13 RUS91800.1 - 1.4 9.5 4.8 7.9 7.1 4.8 2.1 1 1 0 1 1 1 0 SEP domain NUDIX PF00293.28 RUS91801.1 - 2.4e-21 76.1 0.0 3.2e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAGH_C PF16123.5 RUS91802.1 - 4.4e-23 81.6 0.3 6.8e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RUS91802.1 - 3e-16 60.0 2.5 1.2e-15 58.0 2.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 RUS91802.1 - 1.3e-05 25.2 0.1 2.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 RUS91802.1 - 0.00014 21.4 0.3 0.00026 20.5 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CBS PF00571.28 RUS91803.1 - 1.8e-32 111.5 3.5 1.4e-08 35.1 0.1 4.4 4 0 0 4 4 4 4 CBS domain N2227 PF07942.12 RUS91803.1 - 0.043 13.0 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 N2227-like protein Rib_5-P_isom_A PF06026.14 RUS91804.1 - 7e-64 214.6 0.0 9.1e-64 214.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 RUS91804.1 - 0.00036 19.7 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 RUS91804.1 - 0.0018 18.2 0.5 0.13 12.2 0.1 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain CUB PF00431.20 RUS91805.1 - 1.6e-05 25.2 0.0 3.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 CUB domain Gal_Lectin PF02140.18 RUS91806.1 - 1.6e-06 28.4 5.0 0.023 15.1 4.5 2.6 1 1 1 2 2 2 2 Galactose binding lectin domain Ribosomal_L37ae PF01780.19 RUS91806.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family EphA2_TM PF14575.6 RUS91807.1 - 0.036 14.9 0.0 0.09 13.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 RUS91807.1 - 0.14 11.5 0.1 0.14 11.5 0.1 2.6 2 1 1 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) LapA_dom PF06305.11 RUS91807.1 - 3.2 7.6 4.5 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Adeno_E3_CR2 PF02439.15 RUS91808.1 - 0.23 11.2 0.3 0.48 10.2 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gal_Lectin PF02140.18 RUS91808.1 - 2 8.9 4.6 19 5.8 4.6 2.3 1 1 0 1 1 1 0 Galactose binding lectin domain fn3 PF00041.21 RUS91811.1 - 4.3e-89 293.0 37.4 1e-13 51.4 0.1 11.5 10 2 0 10 10 10 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 RUS91811.1 - 1.1e-30 106.1 28.9 3.3e-09 37.2 1.2 10.5 8 3 0 8 8 8 7 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 RUS91811.1 - 6.3e-18 65.0 4.9 0.079 13.3 0.0 9.3 10 0 0 10 10 10 5 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 RUS91811.1 - 3.7e-09 36.9 5.6 1.2 9.6 0.0 7.4 10 0 0 10 10 10 4 Uncharacterised conserved protein (DUF2369) Glyco_hydro_36C PF16874.5 RUS91811.1 - 6.8e-05 23.3 0.2 3.3 8.3 0.0 6.4 7 0 0 7 7 7 1 Glycosyl hydrolase family 36 C-terminal domain DUF756 PF05506.12 RUS91811.1 - 1.8 9.5 3.8 22 6.0 0.2 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF756) DUF5523 PF17661.1 RUS91811.1 - 2.8 7.6 15.9 4.9 6.8 15.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Glyco_hydro_56 PF01630.18 RUS91812.1 - 2.9e-78 263.2 0.0 5.6e-78 262.3 0.0 1.4 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 RUS91812.1 - 0.0023 18.2 1.2 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 RUS91812.1 - 0.015 15.7 9.2 0.17 12.3 1.3 2.7 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 RUS91812.1 - 0.17 12.6 3.7 1.5 9.5 0.2 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF DSPc PF00782.20 RUS91813.1 - 1.1e-39 135.3 0.0 1.8e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RUS91813.1 - 1.2e-08 35.4 0.0 7.5e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 RUS91813.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KIP1 PF07765.12 RUS91816.1 - 0.0069 16.5 3.9 0.0069 16.5 3.9 3.5 3 0 0 3 3 3 1 KIP1-like protein ATG16 PF08614.11 RUS91816.1 - 0.017 15.3 49.5 0.11 12.7 23.8 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 RUS91816.1 - 0.018 15.3 16.4 0.21 11.9 0.7 4.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 RUS91816.1 - 0.059 13.7 33.5 1 9.7 9.0 4.9 1 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 RUS91816.1 - 0.33 9.8 54.7 0.04 12.8 22.9 3.1 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 RUS91816.1 - 0.34 11.0 50.4 0.19 11.8 16.4 4.9 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 RUS91816.1 - 0.4 9.3 40.1 0.59 8.7 19.3 2.7 1 1 0 2 2 2 0 AAA domain DUF2935 PF11155.8 RUS91816.1 - 0.86 9.9 6.1 0.75 10.1 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Lebercilin PF15619.6 RUS91816.1 - 1.2 8.8 51.9 0.061 13.0 19.2 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 RUS91816.1 - 2 8.6 38.7 0.31 11.2 9.1 4.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 RUS91816.1 - 2.8 7.6 41.7 5 6.8 32.6 3.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 RUS91816.1 - 3 7.1 37.7 5.4 6.3 10.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 RUS91816.1 - 3 8.5 50.5 0.56 10.8 13.9 5.2 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 RUS91816.1 - 6.8 7.2 57.8 3.1 8.3 22.4 4.5 2 1 2 4 4 4 0 Apg6 coiled-coil region Tup_N PF08581.10 RUS91816.1 - 8 6.8 32.0 0.19 12.1 8.6 4.5 1 1 3 4 4 4 0 Tup N-terminal DSPc PF00782.20 RUS91818.1 - 4e-21 75.2 0.1 7.1e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ras PF00071.22 RUS91819.1 - 5.1e-25 88.0 0.0 6.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS91819.1 - 1.5e-08 34.9 0.0 2.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RUS91819.1 - 0.00026 20.9 0.0 0.084 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RUS91819.1 - 0.019 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hpr_kinase_C PF07475.12 RUS91819.1 - 0.028 14.0 0.0 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain GTP_EFTU PF00009.27 RUS91819.1 - 0.044 13.3 0.1 0.25 10.9 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activ_2 PF14532.6 RUS91819.1 - 0.072 13.2 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 RUS91819.1 - 0.13 11.5 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 RUS91819.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_C13 PF01650.18 RUS91820.1 - 9.9e-75 251.3 0.6 1.4e-74 250.9 0.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family NuA4 PF09340.10 RUS91821.1 - 2.3e-27 94.7 1.0 2.3e-27 94.7 1.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Med3 PF11593.8 RUS91821.1 - 0.0034 16.6 10.2 0.0035 16.6 10.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal QWRF PF04484.12 RUS91821.1 - 0.013 15.3 4.8 0.014 15.1 4.8 1.2 1 0 0 1 1 1 0 QWRF family SRP-alpha_N PF04086.13 RUS91821.1 - 3.9 7.3 15.8 4.7 7.0 15.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ank_2 PF12796.7 RUS91822.1 - 1e-13 51.7 0.0 1.3e-07 32.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91822.1 - 1.9e-13 50.6 0.1 0.00027 21.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91822.1 - 1.5e-11 43.4 0.1 0.014 15.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 RUS91822.1 - 8.2e-11 41.9 0.2 0.002 18.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RUS91822.1 - 2.4e-09 37.3 0.2 0.001 19.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Mito_carr PF00153.27 RUS91825.1 - 1.2e-20 73.2 1.0 1.7e-08 34.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Baculo_helicase PF04735.12 RUS91825.1 - 0.21 9.1 0.0 0.27 8.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase COQ7 PF03232.13 RUS91826.1 - 0.05 13.4 0.5 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Ncstrn_small PF18266.1 RUS91826.1 - 0.15 12.1 6.6 84 3.1 6.6 3.0 1 1 0 1 1 1 0 Nicastrin small lobe Ribosomal_L4 PF00573.22 RUS91827.1 - 7.6e-42 143.2 0.2 1.6e-41 142.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 RUS91827.1 - 9.8e-27 92.8 4.7 9.8e-27 92.8 4.7 2.7 3 1 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain DUF1360 PF07098.11 RUS91827.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) DUF3913 PF13052.6 RUS91827.1 - 0.14 12.4 0.4 0.58 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) RRM_7 PF16367.5 RUS91828.1 - 1.1e-36 124.8 0.0 9.7e-35 118.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 RUS91828.1 - 1.8e-20 72.9 7.9 4.5e-20 71.6 7.9 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 RUS91828.1 - 2.9e-11 43.0 0.0 4.5e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 RUS91828.1 - 1.6 9.0 7.4 3.4 7.9 7.4 1.5 1 0 0 1 1 1 0 B-box zinc finger 7tm_1 PF00001.21 RUS91829.1 - 4.1e-19 68.9 18.5 5.1e-19 68.6 18.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91829.1 - 2.3e-05 23.9 20.0 4.3e-05 23.0 20.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sigma_reg_N PF13800.6 RUS91829.1 - 2.8 8.3 7.0 3.4 8.0 0.1 3.1 3 1 0 3 3 3 0 Sigma factor regulator N-terminal BTB_2 PF02214.22 RUS91830.1 - 3.1e-18 65.9 0.1 5.1e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.14 RUS91832.1 - 2.8e-66 224.1 17.9 5.7e-66 223.1 17.9 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 RUS91832.1 - 4.4e-37 126.1 1.2 4.4e-37 126.1 1.2 2.8 3 0 0 3 3 3 1 NHR1 homology to TAF FapA PF03961.13 RUS91833.1 - 1.9e-05 23.5 11.0 0.00031 19.5 1.4 2.4 2 1 0 2 2 2 2 Flagellar Assembly Protein A Sarcoglycan_1 PF04790.13 RUS91833.1 - 0.23 10.8 27.9 0.13 11.6 4.1 3.4 2 2 1 3 3 3 0 Sarcoglycan complex subunit protein Pox_D5 PF03288.16 RUS91834.1 - 0.0059 17.1 0.4 0.0086 16.5 0.4 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 RUS91834.1 - 0.02 14.9 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RFX_DNA_binding PF02257.15 RUS91834.1 - 0.032 14.9 0.1 0.066 13.9 0.1 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain RD3 PF14473.6 RUS91834.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RD3 protein LSM14 PF12701.7 RUS91835.1 - 6.2e-30 103.1 0.0 7.5e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 RUS91835.1 - 6.4e-07 29.4 0.0 8.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Transposase_1 PF01359.18 RUS91838.1 - 2.5e-05 24.0 0.1 4.4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Sigma70_r4 PF04545.16 RUS91838.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 RUS91838.1 - 0.048 13.5 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 RUS91838.1 - 0.063 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fibrinogen_C PF00147.18 RUS91840.1 - 2.2e-60 204.2 3.7 3e-60 203.8 3.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS91840.1 - 3.2e-06 27.2 11.9 0.00012 22.2 0.1 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RUS91840.1 - 0.00011 22.1 3.9 0.00029 20.7 3.9 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 RUS91840.1 - 0.00043 20.6 16.0 0.0021 18.3 2.6 3.9 2 2 1 3 3 3 2 Domain of unknown function (DUF5082) CdvA PF18822.1 RUS91840.1 - 0.00046 20.0 7.2 0.025 14.4 1.3 3.5 2 1 1 3 3 3 1 CdvA-like coiled-coil domain DUF1664 PF07889.12 RUS91840.1 - 0.00088 19.3 5.1 0.12 12.4 1.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF2884 PF11101.8 RUS91840.1 - 0.0025 17.4 5.2 0.13 11.8 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2884) Fzo_mitofusin PF04799.13 RUS91840.1 - 0.0031 17.1 1.0 0.0031 17.1 1.0 2.3 1 1 1 2 2 2 1 fzo-like conserved region GAS PF13851.6 RUS91840.1 - 0.006 16.0 4.3 0.013 14.9 4.3 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ApoO PF09769.9 RUS91840.1 - 0.0078 16.2 0.3 0.059 13.3 0.0 2.4 2 1 0 3 3 2 1 Apolipoprotein O DUF4795 PF16043.5 RUS91840.1 - 0.0088 15.7 3.9 0.0088 15.7 3.9 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4795) Tektin PF03148.14 RUS91840.1 - 0.011 14.5 3.5 0.014 14.2 2.4 1.7 1 1 0 1 1 1 0 Tektin family CLZ PF16526.5 RUS91840.1 - 0.018 15.4 4.7 0.057 13.8 3.4 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Filament PF00038.21 RUS91840.1 - 0.019 14.6 2.3 0.02 14.5 1.2 1.5 1 1 0 1 1 1 0 Intermediate filament protein HAP1_N PF04849.13 RUS91840.1 - 0.019 14.2 4.7 0.031 13.5 4.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF3584 PF12128.8 RUS91840.1 - 0.019 12.5 6.5 0.0044 14.6 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 RUS91840.1 - 0.019 15.3 1.3 0.038 14.3 0.4 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG17 PF04108.12 RUS91840.1 - 0.02 14.1 6.9 0.032 13.4 6.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF4164 PF13747.6 RUS91840.1 - 0.034 14.4 9.7 0.033 14.5 3.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) HMMR_N PF15905.5 RUS91840.1 - 0.042 13.3 4.6 0.06 12.8 4.2 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phasin PF05597.11 RUS91840.1 - 0.043 13.8 3.4 0.1 12.6 1.3 2.3 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 RUS91840.1 - 0.046 13.1 3.4 0.065 12.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Collagen_mid PF15984.5 RUS91840.1 - 0.064 13.0 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region ApoLp-III PF07464.11 RUS91840.1 - 0.068 13.3 4.1 1.7 8.7 0.2 2.5 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RmuC PF02646.16 RUS91840.1 - 0.078 12.1 3.1 0.2 10.8 0.3 2.2 2 0 0 2 2 2 0 RmuC family MRF_C1 PF13887.6 RUS91840.1 - 0.092 11.9 5.0 3.6 6.8 0.4 3.3 1 1 2 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 DUF3450 PF11932.8 RUS91840.1 - 0.1 11.9 2.2 0.11 11.8 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Lectin_N PF03954.14 RUS91840.1 - 0.16 11.7 2.9 0.46 10.2 1.9 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Gp-FAR-1 PF05823.12 RUS91840.1 - 0.2 12.0 1.1 0.53 10.6 0.6 2.0 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) YlqD PF11068.8 RUS91840.1 - 0.21 12.0 2.8 1.6 9.1 2.4 2.3 1 1 0 1 1 1 0 YlqD protein Img2 PF05046.14 RUS91840.1 - 0.24 11.7 1.2 0.65 10.3 0.2 2.2 3 0 0 3 3 1 0 Mitochondrial large subunit ribosomal protein (Img2) FAM184 PF15665.5 RUS91840.1 - 0.25 11.1 3.0 0.35 10.6 1.4 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Jnk-SapK_ap_N PF09744.9 RUS91840.1 - 0.28 11.4 9.6 0.032 14.5 4.6 2.0 2 1 0 2 2 1 0 JNK_SAPK-associated protein-1 YtxH PF12732.7 RUS91840.1 - 0.35 11.4 3.8 9.7 6.8 1.9 2.8 2 1 1 3 3 2 0 YtxH-like protein NPV_P10 PF05531.12 RUS91840.1 - 0.36 11.3 4.9 1.1 9.8 0.2 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 RUS91840.1 - 0.43 10.6 8.0 0.28 11.2 1.6 2.6 1 1 2 3 3 3 0 Laminin Domain II Tropomyosin_1 PF12718.7 RUS91840.1 - 0.53 10.4 10.0 0.4 10.8 7.1 2.1 1 1 2 3 3 3 0 Tropomyosin like Prominin PF05478.11 RUS91840.1 - 0.61 8.0 8.0 0.73 7.7 6.7 1.5 1 1 0 1 1 1 0 Prominin HsbA PF12296.8 RUS91840.1 - 0.84 10.1 6.7 0.73 10.3 1.1 2.7 1 1 2 3 3 3 0 Hydrophobic surface binding protein A YojJ PF10372.9 RUS91840.1 - 1.1 9.5 4.7 13 5.9 0.1 3.0 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus SHE3 PF17078.5 RUS91840.1 - 1.2 8.8 10.7 0.094 12.4 1.2 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GreA_GreB_N PF03449.15 RUS91840.1 - 1.4 9.1 4.8 0.66 10.2 0.3 2.4 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal SF-assemblin PF06705.11 RUS91840.1 - 1.4 8.2 14.3 0.31 10.3 2.5 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin Rad50_zn_hook PF04423.14 RUS91840.1 - 1.5 8.7 5.9 29 4.6 0.1 4.2 3 1 1 4 4 4 0 Rad50 zinc hook motif COG5 PF10392.9 RUS91840.1 - 2.1 8.5 9.5 0.37 11.0 1.7 2.8 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Exonuc_VII_L PF02601.15 RUS91840.1 - 2.6 7.5 8.3 11 5.5 8.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit ACCA PF03255.14 RUS91840.1 - 2.8 7.8 4.9 2.4 8.0 0.9 2.5 1 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1451 PF07295.11 RUS91840.1 - 3.2 7.8 5.9 33 4.5 2.6 2.5 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF4618 PF15397.6 RUS91840.1 - 3.2 7.1 9.6 0.82 9.0 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 RUS91840.1 - 3.5 7.8 12.2 0.44 10.7 2.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sipho_Gp157 PF05565.11 RUS91840.1 - 3.7 7.5 10.6 9.3 6.2 0.2 3.1 2 1 1 3 3 3 0 Siphovirus Gp157 DUF3552 PF12072.8 RUS91840.1 - 4.2 6.7 9.7 0.6 9.5 5.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HSBP1 PF06825.12 RUS91840.1 - 5.3 7.0 11.2 5 7.1 1.4 4.2 3 2 0 3 3 3 0 Heat shock factor binding protein 1 Prefoldin_2 PF01920.20 RUS91840.1 - 8.2 6.4 10.8 1.4 8.9 3.4 3.4 3 1 0 3 3 2 0 Prefoldin subunit Med9 PF07544.13 RUS91840.1 - 8.7 6.5 8.9 6.4 6.9 4.9 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Fibrinogen_C PF00147.18 RUS91841.1 - 5.5e-17 62.3 0.0 7.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Baculo_PEP_C PF04513.12 RUS91841.1 - 4.3e-05 23.6 1.3 0.0002 21.4 0.1 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RUS91841.1 - 4.5e-05 23.4 2.1 8.8e-05 22.5 2.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4455 PF14643.6 RUS91841.1 - 0.00043 19.1 3.6 0.00056 18.7 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF5082 PF16888.5 RUS91841.1 - 0.00061 20.1 4.3 0.0032 17.7 2.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 RUS91841.1 - 0.0011 18.6 0.8 0.0028 17.2 0.8 1.8 1 0 0 1 1 1 1 fzo-like conserved region DUF3584 PF12128.8 RUS91841.1 - 0.0046 14.6 2.5 0.0054 14.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ApoO PF09769.9 RUS91841.1 - 0.0077 16.2 0.1 0.051 13.5 0.0 2.3 2 1 0 2 2 2 1 Apolipoprotein O AAA_13 PF13166.6 RUS91841.1 - 0.0088 14.7 1.4 0.012 14.3 1.4 1.1 1 0 0 1 1 1 1 AAA domain DUF4795 PF16043.5 RUS91841.1 - 0.0096 15.5 3.4 0.031 13.9 3.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) CdvA PF18822.1 RUS91841.1 - 0.014 15.2 7.0 0.034 14.0 1.4 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain GAS PF13851.6 RUS91841.1 - 0.014 14.7 2.9 0.029 13.7 2.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 RUS91841.1 - 0.015 15.6 0.2 0.03 14.6 0.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Jnk-SapK_ap_N PF09744.9 RUS91841.1 - 0.017 15.4 4.0 0.017 15.4 4.0 1.9 2 1 0 2 2 1 0 JNK_SAPK-associated protein-1 HSBP1 PF06825.12 RUS91841.1 - 0.026 14.4 9.5 0.37 10.7 0.7 3.7 2 1 1 3 3 3 0 Heat shock factor binding protein 1 CLZ PF16526.5 RUS91841.1 - 0.03 14.7 5.9 0.4 11.1 5.6 3.1 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4164 PF13747.6 RUS91841.1 - 0.034 14.4 6.0 0.034 14.4 1.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Gp-FAR-1 PF05823.12 RUS91841.1 - 0.039 14.3 0.2 0.07 13.5 0.2 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FliD_C PF07195.12 RUS91841.1 - 0.04 13.3 1.7 0.096 12.1 0.8 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Laminin_II PF06009.12 RUS91841.1 - 0.045 13.8 0.5 0.11 12.5 0.5 1.8 1 0 0 1 1 1 0 Laminin Domain II Streptin-Immun PF11083.8 RUS91841.1 - 0.048 14.1 0.3 0.13 12.6 0.2 1.8 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein DUF3375 PF11855.8 RUS91841.1 - 0.051 12.5 1.7 0.84 8.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3375) Lectin_N PF03954.14 RUS91841.1 - 0.06 13.1 4.8 0.13 12.0 1.0 2.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Exonuc_VII_L PF02601.15 RUS91841.1 - 0.083 12.5 1.0 0.14 11.7 1.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SidE PF12252.8 RUS91841.1 - 0.084 10.4 1.9 0.11 10.1 1.9 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein ApoC-I PF04691.12 RUS91841.1 - 0.092 12.7 0.9 0.41 10.6 0.2 2.2 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) SF-assemblin PF06705.11 RUS91841.1 - 0.1 11.9 3.3 0.62 9.4 3.3 2.0 1 1 0 1 1 1 0 SF-assemblin/beta giardin MRF_C1 PF13887.6 RUS91841.1 - 0.15 11.2 4.7 4 6.7 0.3 3.3 1 1 2 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 DUF1664 PF07889.12 RUS91841.1 - 0.17 11.9 3.8 0.36 10.9 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 RUS91841.1 - 0.18 11.2 6.2 0.13 11.7 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Phasin PF05597.11 RUS91841.1 - 0.19 11.7 3.1 0.23 11.5 1.4 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 RUS91841.1 - 0.2 12.1 0.9 1.1 9.8 0.7 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 RUS91841.1 - 0.26 11.5 3.2 0.23 11.6 1.0 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 RUS91841.1 - 0.41 10.8 6.9 1 9.5 6.9 1.6 1 1 0 1 1 1 0 Tropomyosin like YtxH PF12732.7 RUS91841.1 - 0.75 10.4 2.6 7.2 7.2 2.6 2.4 1 1 0 1 1 1 0 YtxH-like protein Prefoldin_2 PF01920.20 RUS91841.1 - 1.2 9.1 7.2 4.6 7.2 4.5 3.0 1 1 0 1 1 1 0 Prefoldin subunit Syntaxin_2 PF14523.6 RUS91841.1 - 5.5 7.4 6.7 27 5.2 0.6 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Rad50_zn_hook PF04423.14 RUS91841.1 - 7.3 6.5 6.8 41 4.1 0.1 3.8 2 1 1 4 4 3 0 Rad50 zinc hook motif 7tm_1 PF00001.21 RUS91842.1 - 2.8e-15 56.3 5.5 4.8e-15 55.6 5.5 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS91842.1 - 3.2e-10 40.1 10.0 6.1e-10 39.2 10.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Gate PF07670.14 RUS91842.1 - 4.1 7.7 10.3 0.22 11.8 1.1 2.8 3 0 0 3 3 3 0 Nucleoside recognition Fib_alpha PF08702.10 RUS91844.1 - 0.39 10.9 9.9 0.18 12.0 4.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 RUS91844.1 - 2.7 7.9 8.2 3.4 7.5 0.6 3.1 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TMF_TATA_bd PF12325.8 RUS91844.1 - 9.7 6.4 20.6 5.6 7.2 8.3 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 RUS91845.1 - 3.8 6.8 10.3 9.2 5.5 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Transmemb_17 PF09799.9 RUS91846.1 - 5.5e-31 107.3 17.1 7.5e-31 106.9 17.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF4233 PF14017.6 RUS91846.1 - 9.4 6.6 16.5 12 6.3 14.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Thiolase_N PF00108.23 RUS91847.1 - 3.6e-94 314.9 1.9 3.6e-94 314.9 1.9 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RUS91847.1 - 8.1e-43 145.0 1.2 8.1e-43 145.0 1.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RUS91847.1 - 7.8e-05 22.4 4.6 0.00014 21.6 2.8 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ank_2 PF12796.7 RUS91848.1 - 6.9e-23 81.1 9.0 5e-17 62.3 1.5 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS91848.1 - 6.2e-16 58.2 5.1 2.4e-08 34.1 0.9 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RUS91848.1 - 6.7e-14 51.6 2.2 0.00034 20.9 0.3 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RUS91848.1 - 1.6e-12 47.7 11.0 9.9e-07 29.2 0.9 4.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91848.1 - 9.4e-09 34.8 0.5 0.24 12.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Fibrinogen_C PF00147.18 RUS91849.1 - 9.4e-22 77.9 2.2 7.1e-21 75.0 0.2 2.2 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 RUS91849.1 - 0.021 14.7 5.1 0.041 13.8 5.0 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4795 PF16043.5 RUS91849.1 - 0.04 13.5 14.9 0.033 13.8 6.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF3410 PF11890.8 RUS91849.1 - 0.041 13.7 0.4 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) GPW_gp25 PF04965.14 RUS91849.1 - 0.053 13.3 2.3 1.3 8.9 0.2 2.9 1 1 2 3 3 3 0 Gene 25-like lysozyme UPF0061 PF02696.14 RUS91849.1 - 0.13 11.0 5.3 0.16 10.7 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF883 PF05957.13 RUS91849.1 - 0.31 11.7 1.8 5.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF572 PF04502.13 RUS91849.1 - 0.36 10.4 6.6 0.42 10.2 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) WXG100 PF06013.12 RUS91849.1 - 0.37 11.1 4.4 0.85 9.9 0.3 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 RUS91849.1 - 0.56 10.2 16.9 0.62 10.1 8.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 RUS91849.1 - 6.1 6.4 8.9 3.2 7.3 1.8 2.4 1 1 1 2 2 2 0 fzo-like conserved region ADH_zinc_N PF00107.26 RUS91850.1 - 9.7e-16 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RUS91850.1 - 5.3e-09 35.9 0.0 9.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 RUS91850.1 - 2.6e-06 28.5 0.0 4.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PapD-like PF14874.6 RUS91851.1 - 5.2e-10 39.4 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like 7TM_GPCR_Srw PF10324.9 RUS91852.1 - 1.2e-05 24.8 15.5 1.6e-05 24.4 15.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srbc PF10316.9 RUS91852.1 - 3.8e-05 23.3 6.8 3.8e-05 23.3 6.8 2.8 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.21 RUS91852.1 - 5.8e-05 22.5 6.3 8.5e-05 22.0 6.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS91852.1 - 0.00029 20.5 17.5 0.0011 18.7 16.8 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DDE_Tnp_IS240 PF13610.6 RUS91853.1 - 0.00069 19.9 0.3 0.0012 19.1 0.3 1.4 1 0 0 1 1 1 1 DDE domain Xrn1_D3 PF18194.1 RUS91853.1 - 0.096 12.8 1.4 8 6.6 0.1 2.8 2 1 1 3 3 3 0 Exoribonuclease 1 Domain-3 CH PF00307.31 RUS91855.1 - 4.5e-18 65.4 0.0 6.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 RUS91855.1 - 3.6e-08 32.9 4.0 5.1e-08 32.4 4.0 1.2 1 0 0 1 1 1 1 Calponin family repeat DUF1761 PF08570.10 RUS91856.1 - 1.4e-14 54.4 1.0 1.6e-14 54.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) EF-hand_9 PF14658.6 RUS91857.1 - 0.19 12.1 0.2 6.9 7.1 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain FERM_C PF09380.10 RUS91858.1 - 5e-27 94.1 0.3 1.2e-26 92.9 0.2 1.7 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 RUS91858.1 - 1.4e-21 77.1 0.0 3.5e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 RUS91858.1 - 1.8e-19 69.4 0.5 1.1e-18 66.9 0.3 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 RUS91858.1 - 2.7e-16 59.4 10.1 5.8e-16 58.3 10.1 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 RUS91859.1 - 2.8e-12 47.1 0.0 3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 FERM central domain Y_phosphatase PF00102.27 RUS91860.1 - 4.4e-81 271.9 0.2 7e-81 271.3 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 RUS91860.1 - 1.2e-20 73.6 0.1 2.5e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS91860.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 RUS91860.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RUS91860.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PDZ_2 PF13180.6 RUS91860.1 - 0.019 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PTPlike_phytase PF14566.6 RUS91860.1 - 0.038 14.1 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate PQQ_3 PF13570.6 RUS91863.1 - 0.092 13.3 1.0 0.23 12.0 0.1 2.2 2 0 0 2 2 2 0 PQQ-like domain SPACA9 PF15120.6 RUS91864.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Yae1_N PF09811.9 RUS91865.1 - 0.00061 19.4 0.7 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 1 Essential protein Yae1, N terminal SSXT PF05030.12 RUS91865.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) CAF1-p150_N PF15557.6 RUS91865.1 - 0.12 12.3 1.1 0.16 11.9 0.2 1.5 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA SMC_N PF02463.19 RUS91866.1 - 1.6e-07 31.0 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RUS91866.1 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 RUS91866.1 - 0.023 13.3 0.1 0.033 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain CcmD PF04995.14 RUS91866.1 - 0.42 10.7 1.0 0.71 10.0 0.2 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Crl PF07417.12 RUS91866.1 - 0.67 10.0 5.0 4.1 7.5 0.6 2.2 1 1 1 2 2 2 0 Sigma factor-binding transcriptional regulator Crl Chibby PF14645.6 RUS91868.1 - 5.4e-41 139.6 0.0 6.1e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Chibby family ZapB PF06005.12 RUS91868.1 - 0.0048 17.3 1.6 0.0068 16.8 1.6 1.2 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 RUS91868.1 - 0.048 13.4 0.8 0.09 12.6 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator RhodobacterPufX PF11511.8 RUS91868.1 - 0.23 11.1 0.3 0.38 10.4 0.3 1.3 1 0 0 1 1 1 0 Intrinsic membrane protein PufX RNA_pol_Rpc4 PF05132.14 RUS91869.1 - 1.6e-25 90.3 3.0 2.2e-24 86.6 0.5 3.1 2 1 0 2 2 2 1 RNA polymerase III RPC4 PRR20 PF15708.5 RUS91869.1 - 0.12 12.2 5.4 0.27 11.1 5.4 1.5 1 0 0 1 1 1 0 Proline-rich protein family 20 GRAM PF02893.20 RUS91871.1 - 3.6e-14 52.6 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 RUS91871.1 - 0.00071 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 RUS91871.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain YlaC PF10777.9 RUS91872.1 - 0.14 12.0 1.0 0.19 11.6 1.0 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC Tubulin PF00091.25 RUS91874.1 - 5.4e-53 180.1 0.2 7.3e-53 179.7 0.2 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 RUS91874.1 - 0.056 13.8 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 RUS91874.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like PAN_1 PF00024.26 RUS91876.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 PAN domain Zip PF02535.22 RUS91877.1 - 5.5e-13 48.9 4.6 6e-13 48.7 4.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF5418 PF17439.2 RUS91877.1 - 0.0046 17.0 2.4 0.0065 16.6 2.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5418) Orf78 PF06024.12 RUS91877.1 - 0.27 11.6 1.3 0.42 10.9 1.3 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF1218 PF06749.12 RUS91877.1 - 1.2 9.7 4.5 1.2 9.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) AMP-binding PF00501.28 RUS91878.1 - 9.6e-74 248.5 0.0 1.3e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 RUS91878.1 - 3.4e-22 78.1 1.6 7.7e-22 77.0 1.6 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 RUS91878.1 - 1.1e-06 29.6 0.4 2.2e-06 28.6 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ShK PF01549.24 RUS91878.1 - 0.14 12.7 0.4 0.38 11.3 0.4 1.8 1 0 0 1 1 1 0 ShK domain-like SpoU_methylase PF00588.19 RUS91879.1 - 4.5e-13 49.6 0.0 6.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RUS91879.1 - 0.00049 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding N-SET PF11764.8 RUS91880.1 - 2.8e-20 73.1 1.3 2.8e-20 73.1 1.3 5.3 4 2 2 6 6 6 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 RUS91880.1 - 4.9e-19 69.3 0.6 4.9e-19 69.3 0.6 5.3 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.22 RUS91880.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM70 PF14967.6 RUS91880.1 - 0.29 10.6 0.3 0.98 8.8 0.3 1.9 1 0 0 1 1 1 0 FAM70 protein Mem_trans PF03547.18 RUS91880.1 - 3.4 6.0 6.1 7.7 4.8 6.1 1.7 1 1 0 1 1 1 0 Membrane transport protein Ank_2 PF12796.7 RUS91881.1 - 5.5e-17 62.1 0.0 2.5e-05 24.8 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS91881.1 - 6.3e-14 51.9 0.0 1.4e-05 25.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RUS91881.1 - 9e-13 48.5 0.5 0.3 11.7 0.0 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91881.1 - 1.4e-12 46.6 0.3 0.094 13.3 0.0 6.3 8 0 0 8 8 8 3 Ankyrin repeat SOCS_box PF07525.16 RUS91881.1 - 1.1e-06 28.8 4.2 1.1e-06 28.8 4.2 2.2 2 0 0 2 2 2 1 SOCS box Ank PF00023.30 RUS91881.1 - 6.5e-05 23.2 0.0 1.6 9.3 0.0 5.2 7 0 0 7 7 7 1 Ankyrin repeat GldH_lipo PF14109.6 RUS91882.1 - 0.044 14.5 0.1 68 4.2 0.0 3.6 1 1 4 5 5 5 0 GldH lipoprotein Utp12 PF04003.12 RUS91882.1 - 0.15 12.4 0.8 7.3 6.9 0.8 2.5 1 1 0 1 1 1 0 Dip2/Utp12 Family C2 PF00168.30 RUS91883.1 - 4.8e-40 136.0 0.1 2.3e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 RUS91883.1 - 5.2e-37 127.6 0.1 1e-36 126.6 0.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase BTK PF00779.19 RUS91883.1 - 3.9e-11 42.6 3.6 6.8e-11 41.8 3.6 1.4 1 0 0 1 1 1 1 BTK motif PH PF00169.29 RUS91883.1 - 0.00023 21.6 0.0 0.00079 19.9 0.0 2.0 2 0 0 2 2 2 1 PH domain WD40 PF00400.32 RUS91884.1 - 3.5e-59 195.4 28.4 9.3e-09 35.8 0.1 9.2 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS91884.1 - 3.2e-23 81.8 2.6 6e-06 26.5 0.0 6.0 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 RUS91884.1 - 9.2e-11 42.1 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 RUS91884.1 - 3e-09 36.3 0.0 0.019 13.9 0.0 4.9 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RUS91884.1 - 1.2e-06 28.5 0.0 0.0049 16.8 0.0 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RUS91884.1 - 1.3e-05 24.9 0.5 1.2 9.1 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 RUS91884.1 - 0.00034 20.0 0.7 4.5 6.5 0.0 4.8 3 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RUS91884.1 - 0.00049 18.9 4.9 3.6 6.1 0.1 4.5 3 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RUS91884.1 - 0.0075 15.6 0.0 13 5.0 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain TFIIIC_delta PF12657.7 RUS91884.1 - 0.0098 15.8 1.0 32 4.4 0.0 4.1 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.11 RUS91884.1 - 0.19 10.4 0.9 6.5 5.4 0.0 3.0 3 1 1 4 4 4 0 Nup133 N terminal like DUF4795 PF16043.5 RUS91886.1 - 0.00029 20.5 0.4 0.0073 15.9 0.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 RUS91886.1 - 0.16 12.5 1.9 6.4 7.3 0.5 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RUS91886.1 - 0.23 11.5 1.1 7.6 6.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Linker_histone PF00538.19 RUS91887.1 - 0.0012 19.1 0.1 0.0026 18.1 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family RPW8 PF05659.11 RUS91887.1 - 0.046 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1635 PF07795.11 RUS91888.1 - 0.00093 19.1 2.0 0.002 18.0 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) SSPI PF14098.6 RUS91888.1 - 0.0017 18.5 1.1 0.48 10.6 0.0 3.4 3 0 0 3 3 3 1 Small, acid-soluble spore protein I UCR_UQCRX_QCR9 PF05365.12 RUS91889.1 - 2.2e-17 62.8 2.2 2.4e-17 62.6 2.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Pox_D5 PF03288.16 RUS91890.1 - 0.00017 22.0 0.0 0.00036 21.0 0.0 1.5 1 0 0 1 1 1 1 Poxvirus D5 protein-like zf-B_box PF00643.24 RUS91892.1 - 2.4e-10 40.4 45.4 1.9e-08 34.3 10.8 3.8 4 0 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 RUS91892.1 - 3.8e-08 33.2 12.0 3.8e-08 33.2 12.0 3.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS91892.1 - 3.9e-06 26.6 15.2 3.9e-06 26.6 15.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RUS91892.1 - 7.1e-05 23.1 13.6 7.1e-05 23.1 13.6 3.5 3 0 0 3 3 3 2 Ring finger domain REV PF00424.18 RUS91892.1 - 0.0021 18.0 2.6 0.011 15.7 0.6 2.5 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) zf-RING_5 PF14634.6 RUS91892.1 - 0.0028 17.6 14.7 0.0028 17.6 14.7 3.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RUS91892.1 - 0.0033 17.5 15.2 0.0033 17.5 15.2 3.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING DUF5082 PF16888.5 RUS91892.1 - 0.19 12.0 1.3 1.5 9.1 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) zf-RING_6 PF14835.6 RUS91892.1 - 1.5 8.8 10.7 0.16 11.9 3.9 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF948 PF06103.11 RUS91894.1 - 0.092 13.0 7.4 0.11 12.8 4.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TTL PF03133.15 RUS91895.1 - 0.059 12.5 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family ARA70 PF12489.8 RUS91896.1 - 8.9e-09 35.6 20.1 2.9e-07 30.7 0.0 6.4 5 3 1 6 6 6 2 Nuclear coactivator DUF1387 PF07139.11 RUS91896.1 - 0.041 13.6 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3583 PF12126.8 RUS91896.1 - 0.12 11.8 2.6 0.22 11.0 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3583) Ank_4 PF13637.6 RUS91897.1 - 2.7e-05 24.6 0.1 0.022 15.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS91897.1 - 4.5e-05 23.9 0.0 9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RUS91897.1 - 5.1e-05 23.5 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91897.1 - 0.00053 20.2 0.1 0.032 14.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat KMP11 PF03037.16 RUS91897.1 - 0.028 15.2 7.5 0.54 11.1 0.1 3.7 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 Big_3 PF07523.12 RUS91898.1 - 0.0034 17.6 0.5 18 5.7 0.2 4.0 2 1 2 4 4 4 1 Bacterial Ig-like domain (group 3) DUF4904 PF16247.5 RUS91898.1 - 0.27 11.1 3.0 78 3.1 0.0 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4904) gpW PF02831.15 RUS91898.1 - 3.4 7.6 3.9 2.1e+02 1.9 2.7 3.4 2 1 0 2 2 2 0 gpW Mpv17_PMP22 PF04117.12 RUS91898.1 - 3.9 7.8 17.9 36 4.7 1.6 5.0 1 1 3 4 4 4 0 Mpv17 / PMP22 family Lectin_C PF00059.21 RUS91900.1 - 2.3e-18 66.9 13.4 1e-08 35.9 0.1 4.0 3 1 1 4 4 4 3 Lectin C-type domain WSC PF01822.19 RUS91900.1 - 8.9e-15 54.7 5.7 8.9e-15 54.7 5.7 2.1 2 0 0 2 2 2 1 WSC domain UL45 PF05473.12 RUS91900.1 - 0.03 14.0 5.3 0.35 10.5 0.4 2.6 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like G8 PF10162.9 RUS91901.1 - 2.4e-33 114.8 0.0 4.5e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 G8 domain ILEI PF15711.5 RUS91901.1 - 1.4e-10 41.5 0.0 2.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Interleukin-like EMT inducer Beta_helix PF13229.6 RUS91901.1 - 1.1e-05 25.3 2.3 1.5e-05 24.9 0.3 2.2 3 0 0 3 3 3 1 Right handed beta helix region NosD PF05048.13 RUS91901.1 - 0.0007 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF3834 PF12916.7 RUS91901.1 - 0.084 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DUF4796 PF16044.5 RUS91901.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) WSC PF01822.19 RUS91903.1 - 4.7e-13 49.1 6.5 1.2e-12 47.8 6.5 1.7 1 0 0 1 1 1 1 WSC domain Beta_helix PF13229.6 RUS91903.1 - 4.1e-09 36.5 7.5 7e-07 29.2 0.4 3.6 2 1 1 3 3 3 2 Right handed beta helix region Lectin_C PF00059.21 RUS91903.1 - 4.5e-08 33.8 0.7 1.2e-07 32.4 0.0 2.2 2 0 0 2 2 2 1 Lectin C-type domain G8 PF10162.9 RUS91903.1 - 1.5e-05 25.0 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 G8 domain NosD PF05048.13 RUS91903.1 - 4.6e-05 22.8 0.2 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) ILEI PF15711.5 RUS91903.1 - 0.00025 21.4 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer Chordopox_A33R PF05966.12 RUS91903.1 - 0.14 11.4 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A33R protein 7tm_1 PF00001.21 RUS91904.1 - 3.1e-32 112.0 7.3 5.1e-32 111.2 7.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS91904.1 - 6.8e-08 32.2 10.1 1e-07 31.6 10.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 RUS91904.1 - 0.00022 21.0 4.5 0.00022 21.0 4.5 1.9 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx YrhC PF14143.6 RUS91904.1 - 0.69 10.0 2.8 6.6 6.9 0.1 2.5 2 0 0 2 2 2 0 YrhC-like protein Srg PF02118.21 RUS91904.1 - 2.3 7.8 17.5 0.14 11.8 5.2 2.5 1 1 1 2 2 2 0 Srg family chemoreceptor SDA1 PF05285.12 RUS91906.1 - 0.00017 21.1 25.5 0.00024 20.6 25.5 1.3 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 RUS91906.1 - 0.0011 17.6 18.3 0.0011 17.6 18.3 2.1 1 1 1 2 2 2 1 Mpp10 protein NPR3 PF03666.13 RUS91906.1 - 0.011 14.6 10.6 0.013 14.3 10.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 COPI_C PF06957.11 RUS91906.1 - 0.34 9.6 11.3 0.41 9.4 11.3 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PI3K_1B_p101 PF10486.9 RUS91906.1 - 0.57 7.9 3.6 0.81 7.4 3.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SpoIIIAH PF12685.7 RUS91906.1 - 0.74 9.6 10.7 1.1 9.1 10.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SURF6 PF04935.12 RUS91906.1 - 3.9 7.2 16.1 8.1 6.2 16.1 1.6 1 1 0 1 1 1 0 Surfeit locus protein 6 DUF2151 PF10221.9 RUS91906.1 - 4 5.9 6.1 5.2 5.5 6.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SK_channel PF03530.14 RUS91907.1 - 8.4e-44 148.2 0.1 8.4e-44 148.2 0.1 2.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 RUS91907.1 - 5e-23 81.1 4.0 1.4e-22 79.7 4.0 1.8 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 RUS91907.1 - 5e-16 58.4 0.6 5e-16 58.4 0.6 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RUS91907.1 - 0.036 13.3 11.6 0.1 11.8 11.6 1.8 1 1 0 1 1 1 0 Ion transport protein rve PF00665.26 RUS91908.1 - 4.3e-14 52.7 0.0 6.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1065 PF06358.11 RUS91909.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) Protoglobin PF11563.8 RUS91910.1 - 0.099 12.5 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 Protoglobin Asparaginase_2 PF01112.18 RUS91911.1 - 1.1e-46 159.2 0.3 7.6e-24 84.3 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Methyltransf_22 PF13383.6 RUS91912.1 - 5.7e-19 68.7 4.8 8e-19 68.2 4.8 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 RUS91912.1 - 1e-05 25.6 0.2 0.00024 21.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase FkbM domain PDEase_I PF00233.19 RUS91914.1 - 6.7e-63 212.6 12.0 3.9e-38 131.5 2.8 2.4 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase PAS_9 PF13426.7 RUS91914.1 - 1.9e-12 47.4 0.0 4.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 RUS91914.1 - 3e-11 43.3 0.0 2.1e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 RUS91914.1 - 4.5e-08 33.3 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 RUS91914.1 - 2.7e-06 27.6 0.0 5.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 RUS91914.1 - 0.0004 20.3 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_12 PF18095.1 RUS91914.1 - 0.0086 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain RGS PF00615.19 RUS91916.1 - 2e-30 105.5 4.6 4.1e-30 104.5 4.6 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RBD PF02196.15 RUS91916.1 - 1.1e-29 102.3 0.0 7.5e-18 64.4 0.0 2.9 2 0 0 2 2 2 2 Raf-like Ras-binding domain PDZ PF00595.24 RUS91916.1 - 5.7e-09 36.2 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS91916.1 - 5.2e-07 29.4 0.1 1.1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain GoLoco PF02188.17 RUS91916.1 - 0.00072 19.0 0.7 0.0022 17.4 0.7 2.0 1 0 0 1 1 1 1 GoLoco motif PDZ_2 PF13180.6 RUS91916.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF3614 PF12267.8 RUS91916.1 - 0.018 15.5 0.9 0.018 15.5 0.9 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3614) Transpos_assoc PF13963.6 RUS91917.1 - 0.034 14.5 0.0 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 Transposase-associated domain zf-tcix PF14952.6 RUS91919.1 - 2.2e-21 75.2 5.3 4.4e-21 74.2 5.3 1.5 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 RUS91919.1 - 0.026 13.9 1.5 0.059 12.8 1.5 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com Ski_Sno PF02437.17 RUS91920.1 - 6.9e-38 128.7 0.2 1.2e-37 127.9 0.2 1.4 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 RUS91920.1 - 2.9e-32 110.7 4.6 2.9e-32 110.7 4.6 1.9 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Band_7 PF01145.25 RUS91921.1 - 1.1e-20 74.3 1.4 2.5e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF2203 PF09969.9 RUS91924.1 - 0.043 14.5 0.1 0.094 13.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.12 RUS91924.1 - 0.045 14.2 0.1 0.27 11.7 0.1 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RUS91924.1 - 0.064 13.3 0.0 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bcr-Abl_Oligo PF09036.10 RUS91924.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain YgaB PF14182.6 RUS91924.1 - 0.17 12.3 0.2 0.36 11.3 0.2 1.5 1 1 0 1 1 1 0 YgaB-like protein Ribosomal_S11 PF00411.19 RUS91925.1 - 1.2e-27 96.5 0.8 1.8e-27 95.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ifi-6-16 PF06140.13 RUS91925.1 - 0.04 13.8 2.8 0.082 12.8 2.8 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family CBM_14 PF01607.24 RUS91926.1 - 3.1e-06 27.2 3.2 6.4e-06 26.2 3.2 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Trypsin PF00089.26 RUS91927.1 - 1.3e-55 188.6 0.6 1.5e-55 188.4 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 RUS91927.1 - 1.7e-07 32.2 0.0 2.9e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Methyltransf_32 PF13679.6 RUS91928.1 - 4.9e-29 101.4 10.3 1.4e-28 99.9 7.9 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS91928.1 - 0.0043 17.8 0.2 0.014 16.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS91928.1 - 0.12 13.1 0.0 0.58 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DHR-2 PF06920.13 RUS91929.1 - 7.6e-86 288.8 1.0 1.7e-85 287.7 0.1 2.0 2 1 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 RUS91929.1 - 1.9e-65 221.2 0.0 3.3e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 RUS91929.1 - 3.6e-53 180.3 0.0 1.5e-51 175.0 0.2 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins VHP PF02209.19 RUS91931.1 - 4e-14 52.4 1.2 7.4e-14 51.5 1.2 1.5 1 0 0 1 1 1 1 Villin headpiece domain Trypsin_2 PF13365.6 RUS91933.1 - 0.0056 17.6 0.0 0.012 16.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain GST_N_4 PF17172.4 RUS91934.1 - 3.8e-26 91.7 0.0 6.5e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RUS91934.1 - 3.1e-19 68.5 0.0 7.5e-19 67.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS91934.1 - 6.3e-08 32.5 0.0 1.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RUS91934.1 - 2.8e-05 24.4 0.0 0.0001 22.6 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 RUS91934.1 - 0.00085 19.5 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS91934.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RT_RNaseH_2 PF17919.1 RUS91936.1 - 2.9e-30 104.3 0.0 6.8e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 RUS91936.1 - 3e-26 91.8 0.0 5.8e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 RUS91936.1 - 1.3e-17 64.0 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 RUS91936.1 - 1.2e-14 54.1 0.3 1.2e-14 54.1 0.3 3.1 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 RUS91936.1 - 2e-06 28.3 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RUS91936.1 - 2e-05 25.1 0.0 5.6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 RUS91936.1 - 0.082 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease SNF PF00209.18 RUS91937.1 - 6.9e-12 44.8 5.2 8.1e-12 44.6 5.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Methyltransf_11 PF08241.12 RUS91938.1 - 2.6e-18 66.5 0.0 5.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RUS91938.1 - 1.4e-17 64.2 0.0 3.8e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RUS91938.1 - 1.5e-11 44.3 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RUS91938.1 - 1.3e-09 38.1 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RUS91938.1 - 1.5e-08 35.3 0.0 3.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RUS91938.1 - 3.7e-08 33.0 0.0 5.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 RUS91938.1 - 0.0002 21.1 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_15 PF09445.10 RUS91938.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 RUS91938.1 - 0.0032 17.0 0.0 0.0086 15.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 RUS91938.1 - 0.0036 15.9 0.0 0.0047 15.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 RUS91938.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 RUS91938.1 - 0.011 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 RUS91938.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 RUS91938.1 - 0.032 14.2 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase BID PF06393.11 RUS91938.1 - 0.046 13.3 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) MTS PF05175.14 RUS91938.1 - 0.078 12.5 0.0 0.4 10.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 RUS91938.1 - 0.081 12.8 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase tRNA_U5-meth_tr PF05958.11 RUS91938.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 RUS91938.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PAN_1 PF00024.26 RUS91939.1 - 0.00097 19.1 0.6 0.0026 17.7 0.2 1.8 2 0 0 2 2 2 1 PAN domain Pkinase PF00069.25 RUS91940.1 - 2.7e-64 217.1 0.4 4.6e-64 216.3 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 RUS91940.1 - 1.2e-48 163.4 19.2 1.2e-09 38.6 1.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 RUS91940.1 - 1.5e-42 145.7 1.9 1.5e-42 145.7 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1_2 PF13540.6 RUS91940.1 - 1.1e-16 60.1 19.8 2.6e-06 27.1 0.0 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 RUS91940.1 - 5.5e-10 39.0 0.0 9.7e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RUS91940.1 - 0.00075 18.9 0.1 0.0021 17.5 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RUS91940.1 - 0.01 14.6 0.0 0.01 14.6 0.0 2.8 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 RUS91940.1 - 0.051 12.5 0.1 0.12 11.3 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain DUF2508 PF10704.9 RUS91940.1 - 0.47 10.7 5.0 0.71 10.1 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF5401 PF17380.2 RUS91940.1 - 2.2 6.3 11.9 3.5 5.6 11.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RasGEF PF00617.19 RUS91941.1 - 7.2e-21 75.2 0.0 1.2e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RUS91941.1 - 1.9e-10 40.9 0.1 4.5e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif KIND PF16474.5 RUS91943.1 - 1e-06 28.8 10.7 4.2e-05 23.5 0.0 4.6 4 1 1 5 5 5 2 Kinase non-catalytic C-lobe domain Pkinase PF00069.25 RUS91943.1 - 0.00043 19.7 0.3 27 4.0 0.0 4.9 3 2 2 5 5 5 2 Protein kinase domain BSMAP PF12280.8 RUS91943.1 - 1.4 9.1 5.8 0.32 11.2 1.0 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein Tubulin_3 PF14881.6 RUS91945.1 - 0.34 10.6 2.7 0.65 9.7 2.7 1.4 1 0 0 1 1 1 0 Tubulin domain DUF5374 PF17344.2 RUS91946.1 - 4.5e-08 32.9 21.0 5.6 7.0 0.1 7.0 7 0 0 7 7 7 7 Family of unknown function (DUF5374) MBF2 PF15868.5 RUS91946.1 - 0.00078 19.9 1.8 19 5.9 0.0 3.7 1 1 3 5 5 5 1 Transcription activator MBF2 DUF1081 PF06448.11 RUS91946.1 - 0.0094 16.3 3.1 8.3 6.8 0.2 3.0 1 1 2 3 3 3 3 Domain of Unknown Function (DUF1081) CdhC PF03598.15 RUS91946.1 - 0.22 11.4 11.6 11 5.9 1.7 4.0 1 1 3 4 4 4 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Filamin PF00630.19 RUS91946.1 - 1.4 9.8 4.1 4.1 8.3 4.1 1.8 1 1 0 1 1 1 0 Filamin/ABP280 repeat Homeodomain PF00046.29 RUS91947.1 - 2.2e-22 78.7 5.7 3.3e-22 78.1 5.7 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 RUS91947.1 - 0.00017 21.3 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 RUS91947.1 - 0.001 18.9 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Keratin_B2 PF01500.17 RUS91948.1 - 0.00096 19.2 1.3 0.077 13.0 1.3 2.4 1 1 0 1 1 1 1 Keratin, high sulfur B2 protein PMG PF05287.12 RUS91948.1 - 0.052 13.6 7.8 0.25 11.3 7.8 1.9 1 1 0 1 1 1 0 PMG protein ArsA_HSP20 PF17886.1 RUS91948.1 - 1.1 8.9 9.4 61 3.3 3.1 5.2 1 1 1 2 2 2 0 HSP20-like domain found in ArsA DUF4200 PF13863.6 RUS91949.1 - 0.0063 16.9 2.6 0.015 15.7 2.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Death PF00531.22 RUS91949.1 - 0.019 15.1 0.1 0.33 11.1 0.1 2.6 1 1 0 1 1 1 0 Death domain DUF3562 PF12085.8 RUS91949.1 - 0.041 13.5 0.2 0.096 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) DUF1283 PF06932.11 RUS91949.1 - 0.89 9.8 3.5 7.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1283) CAP_N PF01213.19 RUS91950.1 - 0.0057 16.2 0.1 0.059 12.9 0.4 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal MID_MedPIWI PF18296.1 RUS91950.1 - 0.035 13.9 0.4 0.056 13.2 0.4 1.4 1 0 0 1 1 1 0 MID domain of medPIWI Agouti PF05039.12 RUS91950.1 - 0.039 14.7 0.7 0.039 14.7 0.7 2.3 3 0 0 3 3 3 0 Agouti protein CagY_M PF07337.11 RUS91951.1 - 0.014 15.0 3.7 0.25 11.0 0.3 2.4 2 0 0 2 2 2 0 DC-EC Repeat DUF3895 PF13034.6 RUS91951.1 - 0.054 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) DUF4827 PF16109.5 RUS91952.1 - 0.075 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4827) CagY_M PF07337.11 RUS91952.1 - 0.27 10.9 4.5 0.54 9.9 0.5 2.6 2 0 0 2 2 2 0 DC-EC Repeat Fz PF01392.22 RUS91953.1 - 9e-46 155.1 18.7 2e-25 89.6 8.6 3.1 2 1 0 2 2 2 2 Fz domain SH3_1 PF00018.28 RUS91954.1 - 6.4e-09 35.3 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RUS91954.1 - 4.5e-06 26.4 0.0 8.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 RUS91954.1 - 2e-05 24.6 2.5 2e-05 24.6 2.5 3.3 2 1 0 2 2 1 1 Hr1 repeat SH3_3 PF08239.11 RUS91954.1 - 7.1e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain zf-C4H2 PF10146.9 RUS91954.1 - 0.12 12.7 13.8 0.18 12.1 6.6 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein SH3_4 PF06347.13 RUS91954.1 - 0.16 11.8 0.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Seryl_tRNA_N PF02403.22 RUS91954.1 - 0.27 11.5 24.6 1.1 9.5 10.7 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Gp-FAR-1 PF05823.12 RUS91954.1 - 0.6 10.5 15.4 0.061 13.7 7.6 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rx_N PF18052.1 RUS91954.1 - 1.1 9.5 9.5 4.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Rx N-terminal domain Tox-REase-5 PF15648.6 RUS91954.1 - 1.5 9.4 5.4 2.2 8.8 1.6 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 TPR_MLP1_2 PF07926.12 RUS91954.1 - 3.6 7.7 31.5 0.2 11.7 18.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HEPN_MAE_28990 PF18737.1 RUS91954.1 - 4.6 7.1 11.3 0.12 12.3 1.6 2.6 2 1 0 2 2 2 0 MAE_28990/MAE_18760-like HEPN Fib_alpha PF08702.10 RUS91954.1 - 4.8 7.4 19.8 7.5 6.7 1.4 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 RUS91954.1 - 6.5 5.2 4.2 9.1 4.7 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 RUS91954.1 - 7 6.1 20.2 11 5.5 0.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ku_PK_bind PF08785.11 RUS91955.1 - 0.045 13.9 3.7 0.46 10.6 0.2 3.2 3 0 0 3 3 3 0 Ku C terminal domain like NPP1 PF05630.11 RUS91955.1 - 0.16 12.1 1.5 0.44 10.6 1.5 1.7 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) FPRL1_inhibitor PF16104.5 RUS91955.1 - 0.2 11.8 2.2 0.25 11.5 0.5 2.0 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein YlaH PF14036.6 RUS91956.1 - 0.12 12.7 0.3 0.12 12.7 0.3 1.8 2 1 0 2 2 2 0 YlaH-like protein DUF1664 PF07889.12 RUS91958.1 - 6.1e-05 23.1 51.7 0.0016 18.5 0.8 7.6 3 3 7 10 10 10 3 Protein of unknown function (DUF1664) Laminin_II PF06009.12 RUS91958.1 - 6.9e-05 22.9 46.5 0.00017 21.6 11.8 6.8 2 1 4 7 7 7 3 Laminin Domain II Tropomyosin PF00261.20 RUS91958.1 - 0.002 17.5 10.8 0.002 17.5 10.8 6.4 2 2 2 5 5 5 1 Tropomyosin Med21 PF11221.8 RUS91958.1 - 0.0033 17.7 6.8 0.0033 17.7 6.8 6.8 4 3 4 8 8 8 1 Subunit 21 of Mediator complex ADIP PF11559.8 RUS91958.1 - 0.0045 17.1 90.5 0.035 14.2 6.3 7.8 2 2 7 9 9 9 3 Afadin- and alpha -actinin-Binding TetR_C_15 PF17918.1 RUS91958.1 - 0.026 15.2 1.6 0.026 15.2 1.6 2.2 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain PatG_C PF18065.1 RUS91958.1 - 0.037 14.0 1.3 0.48 10.4 0.1 2.7 2 0 0 2 2 2 0 PatG C-terminal SlyX PF04102.12 RUS91958.1 - 0.057 14.0 0.6 0.057 14.0 0.6 10.5 3 3 8 12 12 12 0 SlyX Lebercilin PF15619.6 RUS91958.1 - 0.098 12.3 94.6 0.77 9.4 20.7 6.8 2 2 4 6 6 6 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 RUS91958.1 - 0.14 10.8 56.2 0.045 12.4 14.8 4.3 2 1 1 3 3 3 0 AAA domain Golgin_A5 PF09787.9 RUS91958.1 - 0.23 10.9 79.5 0.031 13.7 22.4 4.9 2 1 2 5 5 5 0 Golgin subfamily A member 5 HMMR_N PF15905.5 RUS91958.1 - 0.59 9.6 94.2 2.5 7.5 26.6 5.8 2 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 RUS91958.1 - 0.81 10.1 85.9 0.33 11.4 13.5 6.4 2 1 4 6 6 6 0 Fez1 Filament PF00038.21 RUS91958.1 - 1.2 8.6 80.9 0.17 11.4 15.1 5.3 2 2 1 4 4 4 0 Intermediate filament protein UPF0242 PF06785.11 RUS91958.1 - 1.8 8.6 78.2 1.5 8.9 16.5 5.6 2 1 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Myosin_tail_1 PF01576.19 RUS91958.1 - 2.2 6.0 88.4 0.015 13.1 18.2 3.6 2 1 0 2 2 2 0 Myosin tail CALCOCO1 PF07888.11 RUS91958.1 - 7 5.4 87.8 1 8.1 42.8 3.4 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like PilJ PF13675.6 RUS91958.1 - 7.8 6.6 9.4 17 5.5 7.4 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.11 RUS91958.1 - 8.4 5.2 89.6 0.54 9.1 18.2 5.4 2 1 3 5 5 5 0 Spc7 kinetochore protein DEFB136 PF17333.2 RUS91959.1 - 0.022 14.7 1.1 0.044 13.7 1.1 1.4 1 0 0 1 1 1 0 Beta defensin 136 DUF5504 PF17608.2 RUS91959.1 - 0.034 14.2 0.8 0.046 13.8 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DUF2062 PF09835.9 RUS91959.1 - 0.038 13.8 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2755 PF10954.8 RUS91959.1 - 0.042 13.8 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Ank_4 PF13637.6 RUS91960.1 - 6.3e-33 112.7 2.0 5.4e-10 39.6 0.0 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 RUS91960.1 - 1e-27 96.5 1.1 9.7e-12 45.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 RUS91960.1 - 2.2e-26 91.1 0.4 0.0015 18.9 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 RUS91960.1 - 1.5e-24 83.3 1.5 0.011 16.2 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 RUS91960.1 - 2.4e-20 72.3 2.0 4.7e-08 33.2 0.1 4.9 1 1 5 6 6 6 4 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 RUS91960.1 - 2.6e-09 37.3 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 RUS91960.1 - 0.00046 20.2 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 RUS91961.1 - 4.9e-64 216.2 0.1 8.2e-64 215.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS91961.1 - 1.5e-48 165.4 0.1 2.2e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS91961.1 - 2.9e-05 24.1 0.0 0.01 15.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RUS91961.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RUS91961.1 - 0.0026 16.6 0.0 0.0026 16.6 0.0 3.5 3 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 RUS91961.1 - 0.0036 16.7 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RUS91961.1 - 0.027 14.1 1.7 0.036 13.7 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Gelsolin PF00626.22 RUS91962.1 - 2.1e-42 142.9 0.1 5.2e-16 58.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Staphostatin_A PF09022.10 RUS91962.1 - 0.0082 16.0 1.1 0.015 15.2 1.1 1.4 1 0 0 1 1 1 1 Staphostatin A PAC4 PF16093.5 RUS91962.1 - 0.023 14.9 0.0 0.072 13.3 0.0 1.8 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 SLC12 PF03522.15 RUS91963.1 - 0.2 10.6 15.1 0.79 8.7 11.4 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Utp14 PF04615.13 RUS91963.1 - 0.29 9.6 31.1 0.12 10.9 12.7 2.1 2 0 0 2 2 2 0 Utp14 protein Apt1 PF10351.9 RUS91963.1 - 0.97 8.2 34.2 1.8 7.3 6.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.17 RUS91963.1 - 1.1 7.9 28.5 1.1 8.0 1.0 2.1 2 0 0 2 2 2 0 Presenilin ig PF00047.25 RUS91964.1 - 0.017 15.3 0.1 0.28 11.4 0.1 2.3 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 RUS91964.1 - 0.021 14.9 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS91964.1 - 0.026 15.1 0.0 0.099 13.3 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 RUS91964.1 - 0.034 14.3 0.1 0.15 12.3 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain Frizzled PF01534.17 RUS91966.1 - 2.8e-133 444.0 20.7 4.4e-133 443.3 20.7 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 RUS91966.1 - 3e-33 114.7 5.3 6.5e-33 113.7 5.3 1.6 1 0 0 1 1 1 1 Fz domain SR-25 PF10500.9 RUS91966.1 - 0.99 9.0 16.9 2 7.9 16.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2_4 PF13894.6 RUS91967.1 - 3.4e-07 30.5 24.7 0.036 14.9 0.1 6.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 RUS91967.1 - 4.7e-05 23.7 24.2 0.0017 18.6 12.5 5.1 3 1 2 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RUS91967.1 - 9e-05 22.7 6.4 0.0075 16.6 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RUS91967.1 - 0.00056 20.1 6.0 0.15 12.4 0.3 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RUS91967.1 - 0.0015 18.9 4.2 0.02 15.4 0.3 6.8 7 0 0 7 7 7 3 Zinc finger, C2H2 type Lactococcin_972 PF09683.10 RUS91967.1 - 0.15 12.7 0.3 13 6.5 0.0 3.2 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) zf-C2H2_6 PF13912.6 RUS91967.1 - 0.86 9.7 32.2 0.7 10.0 0.9 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 RUS91967.1 - 4.4 7.2 5.3 2.8 7.9 0.7 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 RUS91967.1 - 4.5 7.3 10.8 5.2 7.1 0.1 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 RUS91968.1 - 8.7e-118 378.7 265.3 1.5e-05 25.2 2.3 29.6 29 0 0 29 29 29 29 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS91968.1 - 1e-109 354.5 199.7 6.2e-09 35.9 0.4 30.8 30 1 0 30 30 30 22 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS91968.1 - 7.9e-92 293.9 248.6 0.00036 21.1 1.0 29.5 29 0 0 29 29 29 28 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS91968.1 - 1.8e-57 190.6 158.8 0.0005 20.3 2.1 27.5 29 0 0 29 29 28 20 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RUS91968.1 - 6.3e-35 118.6 194.1 0.0015 18.8 1.1 26.7 28 0 0 28 28 26 15 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RUS91968.1 - 1.2e-11 44.8 184.0 0.079 13.3 6.5 25.1 6 6 16 23 23 23 10 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RUS91968.1 - 1.2e-09 37.9 226.4 0.003 17.5 2.3 27.9 29 2 0 29 29 27 15 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS91968.1 - 5.5e-05 22.8 205.8 0.00039 20.1 0.9 28.6 29 1 0 29 29 28 9 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 RUS91968.1 - 0.0002 21.1 0.8 0.0021 17.8 0.6 22.8 26 0 0 26 26 26 6 zinc-finger C2H2-type TerY_C PF15616.6 RUS91968.1 - 0.00041 20.5 0.1 0.00041 20.5 0.1 6.0 6 0 0 6 6 6 1 TerY-C metal binding domain zf-C2HE PF16278.5 RUS91968.1 - 0.00041 20.7 178.7 0.018 15.5 0.2 25.8 12 9 12 24 24 23 7 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 RUS91968.1 - 0.0048 16.7 63.2 0.018 14.8 0.2 15.4 10 4 5 16 16 16 2 GAGA factor zf-C2H2_3rep PF18868.1 RUS91968.1 - 0.0048 17.6 0.8 0.0048 17.6 0.8 14.3 9 4 5 15 15 13 2 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 RUS91968.1 - 0.0055 17.0 28.0 2.7 8.3 0.1 10.2 9 4 2 11 11 11 1 BolA-like protein Zn-ribbon_8 PF09723.10 RUS91968.1 - 0.0059 16.7 0.5 0.0059 16.7 0.5 16.3 12 4 6 18 18 18 3 Zinc ribbon domain zf-Di19 PF05605.12 RUS91968.1 - 0.0091 16.3 3.9 0.0091 16.3 3.9 18.5 13 5 6 21 21 21 8 Drought induced 19 protein (Di19), zinc-binding Trm112p PF03966.16 RUS91968.1 - 0.015 15.8 3.7 2.4 8.8 0.1 5.0 3 1 1 4 4 3 0 Trm112p-like protein Plectin PF00681.20 RUS91968.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat zf-C2H2_8 PF15909.5 RUS91968.1 - 0.13 12.6 116.7 0.83 10.0 1.7 12.5 6 5 8 14 14 14 0 C2H2-type zinc ribbon MT-A70 PF05063.14 RUS91969.1 - 3.5e-59 199.6 0.0 6.4e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Lon_C PF05362.13 RUS91970.1 - 2.1e-82 275.6 0.3 4.4e-82 274.6 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 RUS91970.1 - 1.4e-22 80.6 0.0 3.9e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 RUS91970.1 - 1.8e-17 63.9 0.1 3.4e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 RUS91970.1 - 2.5e-08 34.0 0.0 5.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 RUS91970.1 - 8.4e-07 28.9 0.1 3.7e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 RUS91970.1 - 5.6e-05 23.4 0.1 0.00052 20.3 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 RUS91970.1 - 0.00012 22.6 0.0 0.00044 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 RUS91970.1 - 0.00031 20.9 0.0 0.00097 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 RUS91970.1 - 0.00031 20.6 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RUS91970.1 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 RUS91970.1 - 0.006 17.1 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 RUS91970.1 - 0.0072 15.3 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 RUS91970.1 - 0.015 15.0 0.0 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 RUS91970.1 - 0.031 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 RUS91970.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RUS91970.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 RUS91970.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Clusterin PF01093.17 RUS91970.1 - 0.12 11.4 0.6 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Clusterin Viral_helicase1 PF01443.18 RUS91970.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ECSIT_C PF14784.6 RUS91971.1 - 0.34 11.2 4.3 6.4 7.1 0.0 2.6 1 1 1 2 2 2 0 C-terminal domain of the ECSIT protein TSC22 PF01166.18 RUS91971.1 - 0.41 11.0 6.6 1.3 9.4 0.7 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF3584 PF12128.8 RUS91971.1 - 0.43 8.0 19.9 0.55 7.7 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 RUS91971.1 - 1.2 9.2 22.1 0.052 13.6 16.4 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 RUS91971.1 - 3 5.7 13.7 4.3 5.1 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT_CC PF16559.5 RUS91971.1 - 8.3 6.4 16.3 0.81 9.6 4.2 3.4 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3361 PF11841.8 RUS91972.1 - 4.6e-47 159.8 2.7 8.6e-47 158.9 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 RUS91972.1 - 7.8e-35 120.6 0.0 1.9e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 RUS91972.1 - 4.9e-30 104.8 0.1 1.6e-29 103.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain TUG-UBL1 PF11470.8 RUS91972.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 TUG ubiquitin-like domain V-ATPase_H_C PF11698.8 RUS91972.1 - 0.96 9.6 3.7 0.85 9.8 0.7 2.6 3 0 0 3 3 3 0 V-ATPase subunit H Nop10p PF04135.12 RUS91973.1 - 1.4e-22 79.4 0.3 1.9e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Kdo PF06293.14 RUS91974.1 - 8.7e-10 38.3 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RUS91974.1 - 3.2e-08 33.3 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 RUS91974.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 RUS91974.1 - 0.001 18.5 0.1 0.0016 17.8 0.1 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 RUS91974.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RUS91974.1 - 0.002 18.1 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RUS91974.1 - 0.0052 16.4 0.1 0.0065 16.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 RUS91974.1 - 0.015 14.2 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Sulfotransfer_1 PF00685.27 RUS91975.1 - 1.7e-18 67.1 0.1 2.2e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS91975.1 - 8.5e-10 39.4 0.0 4.6e-06 27.2 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 RUS91976.1 - 1e-25 90.7 0.2 3.2e-25 89.1 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS91976.1 - 1.4e-10 41.9 0.0 1.7e-06 28.6 0.0 2.6 1 1 1 2 2 2 2 Sulfotransferase family CDC45 PF02724.14 RUS91976.1 - 0.48 8.7 19.6 0.68 8.1 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 RUS91976.1 - 1.9 8.0 23.8 2.8 7.4 23.8 1.3 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 RUS91976.1 - 8.3 5.1 17.0 12 4.6 17.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ank_2 PF12796.7 RUS91977.1 - 1.3e-25 89.8 1.6 7.6e-10 39.2 0.7 4.5 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RUS91977.1 - 9.6e-22 77.1 3.9 1e-07 32.3 0.2 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RUS91977.1 - 1.4e-18 65.1 4.0 0.00011 22.3 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 RUS91977.1 - 4.9e-18 64.7 6.4 6.6e-05 23.2 0.1 6.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 RUS91977.1 - 1.6e-13 50.6 4.3 4.4e-06 26.9 0.4 5.3 4 2 1 5 5 5 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 RUS91977.1 - 4e-05 23.9 0.0 8.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SOCS box Sulfotransfer_1 PF00685.27 RUS91978.1 - 4.6e-19 68.9 0.0 6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS91978.1 - 1.2e-10 42.2 0.0 2e-05 25.1 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family PCIF1_WW PF12237.8 RUS91979.1 - 3.2e-68 228.7 0.4 5.3e-68 228.0 0.4 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 RUS91979.1 - 1.2e-10 41.3 1.3 2.4e-10 40.3 1.3 1.5 1 0 0 1 1 1 1 WW domain LBP_BPI_CETP_C PF02886.17 RUS91980.1 - 1.4e-43 149.1 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 RUS91980.1 - 1.9e-23 82.8 0.0 4.5e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Phage_Arf PF17585.2 RUS91980.1 - 0.1 12.6 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Accessory recombination function protein UPF0444 PF15475.6 RUS91980.1 - 0.77 10.1 2.8 3.4 8.0 0.2 2.8 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 LBP_BPI_CETP_C PF02886.17 RUS91981.1 - 1.3e-10 41.1 0.2 1.5e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 RUS91982.1 - 2.6e-19 69.4 0.0 3.6e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 RUS91982.1 - 2.8e-12 46.6 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain POT1PC PF16686.5 RUS91982.1 - 0.034 14.0 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein zf-C2H2_4 PF13894.6 RUS91983.1 - 6e-09 36.0 34.4 0.03 15.1 2.1 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS91983.1 - 5e-05 23.5 37.3 0.059 13.8 0.3 6.5 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.7 RUS91983.1 - 6.8e-05 23.1 14.0 0.027 14.9 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RUS91983.1 - 7.9e-05 23.3 15.0 0.097 13.3 0.0 4.3 3 1 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 RUS91983.1 - 0.00013 22.2 16.2 0.034 14.5 4.8 3.5 2 1 2 4 4 4 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 RUS91983.1 - 0.00069 19.9 3.3 0.00069 19.9 3.3 4.3 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_SprT PF17283.2 RUS91983.1 - 0.025 14.5 11.1 7 6.6 0.0 4.9 5 1 0 5 5 5 0 SprT-like zinc ribbon domain ECSIT_C PF14784.6 RUS91983.1 - 0.034 14.5 0.1 0.099 13.0 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein zf-C2H2_2 PF12756.7 RUS91983.1 - 0.25 11.7 27.1 0.99 9.8 1.5 5.5 2 1 3 5 5 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 RUS91983.1 - 1.1 9.4 19.9 6.9 6.9 2.6 4.8 4 1 1 5 5 5 0 Zinc ribbon domain zf-Mss51 PF13824.6 RUS91983.1 - 2.1 8.5 6.2 2.7 8.2 1.4 3.1 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYST PF17772.1 RUS91983.1 - 2.6 7.7 11.6 11 5.7 0.1 3.8 3 1 1 4 4 4 0 MYST family zinc finger domain PriA_CRR PF18319.1 RUS91983.1 - 8.1 6.5 12.6 4.2 7.4 0.3 4.3 3 1 1 4 4 4 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2 PF00096.26 RUS91985.1 - 1.5e-36 122.8 124.9 0.00016 22.0 1.4 16.6 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RUS91985.1 - 6.5e-32 108.5 110.2 2.1e-05 24.7 0.4 17.0 16 2 0 16 16 16 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS91985.1 - 1.8e-31 106.0 113.8 0.0064 17.2 1.1 16.5 16 0 0 16 16 16 14 C2H2-type zinc finger zf-H2C2_5 PF13909.6 RUS91985.1 - 4.4e-19 67.9 107.4 5.2e-06 26.1 2.6 13.9 15 1 0 15 15 14 7 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 RUS91985.1 - 4.3e-07 29.9 42.0 0.036 14.1 2.0 8.2 6 2 2 8 8 8 5 Zinc-finger zf-C2H2_jaz PF12171.8 RUS91985.1 - 2.6e-06 27.6 72.8 0.13 12.6 0.5 13.4 14 0 0 14 14 14 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 RUS91985.1 - 3e-06 27.5 77.0 0.0014 18.9 1.6 11.8 3 1 5 11 11 11 5 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 RUS91985.1 - 0.00012 22.0 2.2 0.00012 22.0 2.2 12.4 15 1 0 15 15 14 2 C2H2-type zinc finger zf-C2HE PF16278.5 RUS91985.1 - 0.0032 17.9 71.0 0.077 13.5 0.1 11.9 8 4 3 11 11 11 4 C2HE / C2H2 / C2HC zinc-binding finger DUF237 PF03072.14 RUS91985.1 - 0.025 14.6 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF237) zf-C2H2_9 PF16293.5 RUS91985.1 - 0.069 13.0 0.1 0.069 13.0 0.1 7.8 12 1 1 13 13 12 0 C2H2 type zinc-finger (1 copy) OrsD PF12013.8 RUS91985.1 - 0.07 13.6 0.1 0.07 13.6 0.1 10.4 5 3 5 10 10 10 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met PF12874.7 RUS91985.1 - 0.18 12.3 0.1 0.18 12.3 0.1 13.1 16 0 0 16 16 15 0 Zinc-finger of C2H2 type Trm112p PF03966.16 RUS91985.1 - 2 9.0 0.0 2 9.0 0.0 5.3 5 2 0 5 5 5 0 Trm112p-like protein GCV_T PF01571.21 RUS91986.1 - 1.9e-70 237.2 0.0 1.9e-69 233.9 0.0 2.5 2 1 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 RUS91986.1 - 3e-56 191.5 0.0 4.3e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 RUS91986.1 - 3.3e-23 81.8 0.2 8.5e-23 80.5 0.2 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 RUS91986.1 - 3.6e-11 42.8 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Trp_halogenase PF04820.14 RUS91986.1 - 3.2e-07 29.6 2.7 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 RUS91986.1 - 1e-06 28.2 2.1 0.0072 15.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RUS91986.1 - 5e-05 22.6 1.7 0.00011 21.5 1.7 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 RUS91986.1 - 0.00024 20.4 3.9 0.16 11.2 0.6 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 RUS91986.1 - 0.0025 17.1 0.5 0.76 9.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RUS91986.1 - 0.0064 16.7 2.1 0.012 15.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 RUS91986.1 - 0.0067 16.1 0.2 1.6 8.3 0.2 3.3 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 RUS91986.1 - 0.01 15.8 0.8 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 RUS91986.1 - 0.013 15.7 1.6 0.2 11.9 0.2 2.8 3 0 0 3 3 3 0 TrkA-N domain 3HCDH_N PF02737.18 RUS91986.1 - 0.016 15.1 0.2 5.6 6.8 0.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 RUS91986.1 - 0.064 12.6 0.2 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase SoxG PF04268.12 RUS91986.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Sarcosine oxidase, gamma subunit family FAD_binding_3 PF01494.19 RUS91986.1 - 0.085 12.1 1.6 2.9 7.1 0.2 2.4 2 0 0 2 2 2 0 FAD binding domain DUF1501 PF07394.12 RUS91986.1 - 0.15 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) ThiF PF00899.21 RUS91986.1 - 0.48 9.7 1.9 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.27 RUS91986.1 - 0.67 10.5 14.1 0.3 11.7 0.3 3.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Alpha_kinase PF02816.18 RUS91987.1 - 1.7e-28 100.0 0.0 2.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family NUDIX_4 PF14815.6 RUS91987.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain Abhydrolase_1 PF00561.20 RUS91988.1 - 5.4e-14 52.5 0.1 2e-09 37.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RUS91988.1 - 3.1e-09 37.8 0.0 4.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RUS91988.1 - 2.4e-05 23.8 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RE_LlaJI PF09563.10 RUS91988.1 - 0.0081 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 LlaJI restriction endonuclease Abhydrolase_4 PF08386.10 RUS91988.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 RUS91988.1 - 0.039 13.6 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) TPR_12 PF13424.6 RUS91989.1 - 0.00012 22.3 3.7 0.2 12.0 0.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 RUS91989.1 - 0.00026 21.1 10.0 0.04 14.3 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RUS91989.1 - 0.00092 19.4 14.9 0.3 11.3 0.1 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RUS91989.1 - 0.0016 18.2 13.6 0.31 11.0 0.2 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 RUS91989.1 - 0.0023 17.7 1.1 8.9 6.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 RUS91989.1 - 0.0031 18.0 6.6 13 6.4 0.2 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RUS91989.1 - 0.02 14.9 5.7 1 9.4 0.2 3.8 3 1 1 4 4 4 0 Putative TPR-like repeat TPR_15 PF13429.6 RUS91989.1 - 0.048 12.9 0.4 8.7 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 RUS91989.1 - 0.14 13.1 7.7 2.2 9.3 0.0 5.1 6 2 2 8 8 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 RUS91989.1 - 0.24 11.6 23.1 1.8 8.9 0.6 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 RUS91989.1 - 0.28 11.9 7.5 2.5 8.9 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RUS91989.1 - 0.4 11.0 11.7 5.2 7.5 0.4 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat LLC1 PF14945.6 RUS91990.1 - 7.6e-41 139.4 0.4 8.8e-41 139.2 0.4 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein SSXT PF05030.12 RUS91991.1 - 2.8e-25 87.7 6.1 1.1e-24 85.8 6.1 2.2 1 0 0 1 1 1 1 SSXT protein (N-terminal region) DUF778 PF05608.12 RUS91991.1 - 0.047 14.1 11.0 7.7 6.8 11.0 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF1330 PF07045.11 RUS91992.1 - 0.00073 19.8 0.1 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1330) GST_N_3 PF13417.6 RUS91993.1 - 1.7e-22 79.6 0.0 4e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS91993.1 - 1e-17 64.2 0.0 1.9e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS91993.1 - 3e-17 62.7 0.0 7.4e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RUS91993.1 - 3.1e-06 27.3 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RUS91993.1 - 4.3e-06 26.9 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 RUS91993.1 - 6.5e-06 26.1 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RUS91993.1 - 6.2e-05 23.1 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 RUS91993.1 - 0.029 14.9 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RUS91994.1 - 4.7e-23 81.4 0.1 1.7e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RUS91994.1 - 1.9e-16 60.1 0.1 6.5e-16 58.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 RUS91994.1 - 1.9e-16 60.2 0.0 6.7e-16 58.4 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RUS91994.1 - 1.7e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RUS91994.1 - 3.2e-06 27.1 0.1 8.6e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RUS91994.1 - 4.1e-06 26.9 0.0 9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 RUS91994.1 - 8.2e-05 22.7 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin IncFII_repA PF02387.15 RUS91994.1 - 0.05 12.9 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family GST_C_5 PF16865.5 RUS91994.1 - 0.094 13.3 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MDD_C PF18376.1 RUS91995.1 - 2.6e-76 255.6 0.0 3.6e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 RUS91995.1 - 3e-07 30.6 2.5 6.8e-07 29.4 2.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain ATP-grasp_4 PF13535.6 RUS91995.1 - 0.031 13.9 0.1 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 ATP-grasp domain EF-hand_7 PF13499.6 RUS91996.1 - 6.6e-34 116.2 4.0 7e-17 61.6 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RUS91996.1 - 1.9e-32 108.4 19.4 1.7e-09 36.5 0.1 4.5 5 0 0 5 5 4 4 EF hand EF-hand_6 PF13405.6 RUS91996.1 - 2.9e-29 98.5 7.1 3.1e-09 36.0 0.1 4.7 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 RUS91996.1 - 5.1e-25 87.1 11.7 5.6e-14 51.7 0.7 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 RUS91996.1 - 4.5e-23 79.7 9.2 8.8e-08 31.3 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 RUS91996.1 - 7.2e-13 48.4 1.3 5.8e-06 26.2 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RUS91996.1 - 7.4e-13 48.6 0.2 2.9e-06 27.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 RUS91996.1 - 3.5e-06 27.3 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RUS91996.1 - 0.00019 21.4 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RUS91996.1 - 0.00051 20.9 0.1 0.019 15.8 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 RUS91996.1 - 0.00079 19.5 0.0 0.0052 16.8 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF2267 PF10025.9 RUS91996.1 - 0.0045 17.3 0.1 0.27 11.5 0.1 2.3 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2267) DUF5580 PF17743.1 RUS91996.1 - 0.015 13.9 0.0 0.027 13.0 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5580) Caleosin PF05042.13 RUS91996.1 - 0.034 14.1 0.1 13 5.7 0.0 3.1 2 2 1 3 3 3 0 Caleosin related protein TerB PF05099.13 RUS91996.1 - 0.034 14.1 0.0 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TerB Fer2_2 PF01799.20 RUS91996.1 - 0.051 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 [2Fe-2S] binding domain NOA36 PF06524.12 RUS91996.1 - 0.17 11.1 13.8 0.23 10.7 13.8 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RUS91996.1 - 0.22 9.6 19.3 0.29 9.2 19.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RUS91996.1 - 0.81 7.9 8.3 0.96 7.7 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 RUS91996.1 - 0.88 8.9 11.2 1 8.6 11.2 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RUS91996.1 - 1.2 8.5 13.7 1.5 8.2 13.7 1.1 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 RUS91996.1 - 1.8 6.9 5.1 2 6.8 5.1 1.2 1 0 0 1 1 1 0 SGT1 protein Cwf_Cwc_15 PF04889.12 RUS91996.1 - 3.1 7.5 12.5 4.4 7.0 12.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 RUS91996.1 - 9.9 6.2 8.3 17 5.4 8.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal LCE PF14672.6 RUS91997.1 - 4.7 7.9 7.6 22 5.7 1.0 2.5 2 0 0 2 2 2 0 Late cornified envelope Alpha_kinase PF02816.18 RUS91998.1 - 2.1e-17 63.9 0.0 3.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family LRR_8 PF13855.6 RUS92000.1 - 1.4e-51 172.1 46.5 2.2e-12 46.6 0.4 7.2 3 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 RUS92000.1 - 6.5e-21 74.1 50.4 6.9e-05 23.1 4.4 8.5 4 2 6 10 10 10 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS92000.1 - 9.5e-16 57.9 0.1 5.1e-06 26.5 0.0 4.3 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS92000.1 - 5e-05 23.3 44.0 5.9 7.9 0.1 13.3 15 0 0 15 15 15 3 Leucine Rich Repeat LRR_9 PF14580.6 RUS92000.1 - 0.0016 18.0 12.2 0.24 10.9 0.0 4.4 1 1 4 5 5 5 2 Leucine-rich repeat LRR_6 PF13516.6 RUS92000.1 - 0.043 13.9 43.9 2.8 8.2 0.4 10.8 13 0 0 13 13 13 0 Leucine Rich repeat Adeno_E3_CR2 PF02439.15 RUS92000.1 - 0.096 12.5 0.2 0.096 12.5 0.2 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRRNT PF01462.18 RUS92000.1 - 1.3 8.8 8.2 0.15 11.8 0.6 2.9 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain AA_permease_2 PF13520.6 RUS92001.1 - 3.9e-14 52.3 19.1 4.5e-14 52.1 19.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS92001.1 - 4.1e-05 22.4 12.8 5.3e-05 22.0 12.8 1.2 1 0 0 1 1 1 1 Amino acid permease SR-25 PF10500.9 RUS92001.1 - 8.2 6.0 13.6 10 5.6 13.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RUS92001.1 - 8.3 7.2 9.9 11 6.7 9.9 1.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein AA_permease_2 PF13520.6 RUS92002.1 - 1.1e-65 222.2 43.3 1.4e-65 221.9 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS92002.1 - 5.5e-24 84.6 40.5 9.9e-24 83.8 40.4 1.4 1 1 0 1 1 1 1 Amino acid permease MIP PF00230.20 RUS92003.1 - 7.3e-63 212.3 11.7 8.8e-63 212.0 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Tubulin PF00091.25 RUS92004.1 - 4.9e-44 150.9 0.0 8e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RUS92004.1 - 2.6e-42 143.9 0.1 3.9e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RUS92004.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TRP_2 PF08344.11 RUS92006.1 - 8.1e-21 74.0 3.1 2e-20 72.8 3.1 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 RUS92006.1 - 5.3e-20 71.7 12.2 8.4e-20 71.0 12.2 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 RUS92006.1 - 2.5e-06 28.0 0.0 0.023 15.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RUS92006.1 - 6.5e-06 26.1 0.0 0.32 11.7 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RUS92006.1 - 5.3e-05 23.7 0.0 0.041 14.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RUS92006.1 - 0.00015 22.1 0.0 0.51 10.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RUS92006.1 - 0.00034 20.8 0.0 0.85 10.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ras PF00071.22 RUS92007.1 - 4e-63 211.8 0.2 4.8e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS92007.1 - 1.7e-33 115.4 0.2 4.3e-33 114.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RUS92007.1 - 4.7e-13 49.0 0.0 6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RUS92007.1 - 4.4e-05 23.5 0.0 8.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RUS92007.1 - 0.00025 20.5 0.0 0.00034 20.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RUS92007.1 - 0.00032 20.3 0.1 0.0017 18.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RUS92007.1 - 0.00066 19.6 0.2 0.27 11.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RUS92007.1 - 0.037 14.3 0.1 0.23 11.7 0.1 2.2 1 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 RUS92007.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 RUS92007.1 - 0.12 12.1 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain SHQ1 PF04925.15 RUS92008.1 - 6e-62 208.3 0.9 9.8e-62 207.6 0.9 1.3 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 RUS92008.1 - 0.05 14.0 0.0 0.24 11.8 0.0 2.1 1 0 0 1 1 1 0 PIH1 CS-like domain Scs3p PF10261.9 RUS92009.1 - 4e-22 78.9 12.6 1.3e-19 70.7 12.6 2.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 RUS92009.1 - 0.0049 16.6 1.4 0.011 15.6 0.1 2.1 1 1 0 2 2 2 1 PAP2 superfamily UL40 PF10682.9 RUS92009.1 - 0.045 13.4 0.7 0.071 12.8 0.7 1.4 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 NS3 PF17530.2 RUS92009.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Non-structural protein NS3 Adeno_E3_CR2 PF02439.15 RUS92009.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ubiquitin PF00240.23 RUS92010.1 - 5.4e-09 35.7 0.8 1.9e-08 33.9 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 RUS92010.1 - 0.00012 22.1 0.4 0.00012 22.1 0.4 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RUS92010.1 - 0.00032 21.2 1.6 0.00032 21.2 1.6 2.8 2 2 0 2 2 2 1 DUF2407 ubiquitin-like domain Zip PF02535.22 RUS92010.1 - 0.002 17.4 3.8 0.012 14.8 0.2 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter SKI PF01202.22 RUS92010.1 - 0.051 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Shikimate kinase XRN_M PF17846.1 RUS92010.1 - 0.32 9.9 8.4 2.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Xrn1 helical domain Vps54 PF07928.12 RUS92010.1 - 0.95 9.9 3.5 3.1 8.3 3.5 1.8 1 0 0 1 1 1 0 Vps54-like protein Folliculin PF11704.8 RUS92010.1 - 1.2 8.9 8.4 0.73 9.7 2.1 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FAM176 PF14851.6 RUS92010.1 - 6.6 6.4 9.6 4.7 6.9 1.3 2.6 2 0 0 2 2 2 0 FAM176 family Serinc PF03348.15 RUS92010.1 - 7.2 5.4 0.0 7.2 5.4 0.0 2.9 3 1 0 3 3 3 0 Serine incorporator (Serinc) Nop PF01798.18 RUS92012.1 - 1.3e-78 263.7 0.0 2.1e-78 263.0 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 RUS92012.1 - 2.3e-42 144.7 4.3 2.3e-42 144.7 4.3 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain HHH_2 PF12826.7 RUS92012.1 - 0.0054 16.8 0.3 16 5.7 0.5 3.3 3 0 0 3 3 3 2 Helix-hairpin-helix motif PGI PF00342.19 RUS92013.1 - 1.7e-245 815.2 0.0 1.9e-245 815.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.20 RUS92013.1 - 0.029 14.4 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Urease beta subunit LRR_4 PF12799.7 RUS92014.1 - 1e-15 57.6 24.2 1.5e-08 34.7 2.3 4.6 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS92014.1 - 1.1e-10 41.1 22.8 1.9e-05 24.3 3.0 3.5 1 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 RUS92014.1 - 5.1e-09 35.9 3.9 1.2e-06 28.2 0.8 3.1 3 1 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 RUS92014.1 - 0.00072 19.4 13.2 0.33 11.1 0.1 4.6 3 1 1 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 RUS92014.1 - 1.1 10.1 17.1 17 6.4 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_2 PF07723.13 RUS92014.1 - 3.7 8.4 6.4 1.3e+02 3.5 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat 7tm_1 PF00001.21 RUS92015.1 - 4e-21 75.5 13.9 5.3e-21 75.1 13.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 RUS92015.1 - 4e-10 39.8 12.9 4.3e-10 39.7 12.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 RUS92015.1 - 1e-08 34.9 16.2 5e-07 29.3 16.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 RUS92015.1 - 2.4e-07 30.4 13.4 2.9e-07 30.1 13.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv AA_permease_2 PF13520.6 RUS92016.1 - 3.5e-23 82.1 13.7 4.6e-23 81.7 13.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS92016.1 - 0.00014 20.7 11.3 0.00024 19.9 11.3 1.4 1 1 0 1 1 1 1 Amino acid permease EpsG PF14897.6 RUS92016.1 - 0.22 10.8 5.7 0.037 13.3 1.6 1.7 2 0 0 2 2 2 0 EpsG family YfhO PF09586.10 RUS92016.1 - 2.4 6.3 3.6 3.7 5.6 3.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Porphobil_deam PF01379.20 RUS92017.1 - 1.9e-81 272.4 0.0 2.8e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 RUS92017.1 - 1.3e-15 57.5 0.1 3.1e-14 53.1 0.0 2.7 1 1 1 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L5e PF17144.4 RUS92017.1 - 0.15 12.1 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Gly_transf_sug PF04488.15 RUS92019.1 - 0.00017 22.1 0.0 0.0024 18.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 RUS92019.1 - 0.0041 16.5 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein COMM_domain PF07258.14 RUS92020.1 - 3.8e-12 46.1 0.1 5.6e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 COMM domain DUF1752 PF08550.10 RUS92020.1 - 0.17 11.7 1.2 0.32 10.9 1.2 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) MRAP PF15183.6 RUS92021.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Chlorophyllase2 PF12740.7 RUS92023.1 - 4.2e-32 111.1 0.0 4.2e-31 107.8 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 RUS92023.1 - 4.2e-12 45.7 0.2 1.1e-05 24.6 0.0 3.0 2 1 1 3 3 3 3 Chlorophyllase Hydrolase_4 PF12146.8 RUS92023.1 - 0.012 14.9 0.0 0.86 8.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 p450 PF00067.22 RUS92024.1 - 1.4e-48 165.8 0.1 1.8e-48 165.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CENP-B_dimeris PF09026.10 RUS92024.1 - 0.093 13.1 10.9 0.18 12.2 10.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 RUS92024.1 - 0.56 9.9 1.8 0.99 9.1 1.8 1.4 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 RUS92024.1 - 4.2 7.0 12.9 5.9 6.5 12.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 RUS92024.1 - 6 4.8 10.7 7.6 4.5 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RUS92024.1 - 7 5.9 14.2 9.3 5.5 14.2 1.1 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 RUS92024.1 - 8.8 4.7 5.2 11 4.4 5.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 p450 PF00067.22 RUS92025.1 - 3.1e-94 316.4 0.0 3.7e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.27 RUS92027.1 - 3.2e-25 88.7 0.0 8.7e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.23 RUS92027.1 - 2.3e-06 28.2 0.1 6.2e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RhoGEF PF00621.20 RUS92027.1 - 0.0031 17.8 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 RhoGEF domain Ras_bdg_2 PF14847.6 RUS92027.1 - 0.11 12.9 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 IQ_SEC7_PH PF16453.5 RUS92027.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 PH domain CDC27 PF09507.10 RUS92028.1 - 0.0026 17.2 60.6 0.0033 16.9 60.6 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Macoilin PF09726.9 RUS92028.1 - 0.018 13.7 29.4 0.019 13.5 29.4 1.1 1 0 0 1 1 1 0 Macoilin family Dapper PF15268.6 RUS92028.1 - 0.18 10.7 33.2 0.19 10.5 33.2 1.1 1 0 0 1 1 1 0 Dapper SRP-alpha_N PF04086.13 RUS92028.1 - 0.23 11.4 63.9 0.33 10.9 63.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Red1 PF07964.11 RUS92028.1 - 0.65 8.2 66.3 0.84 7.8 66.3 1.3 1 0 0 1 1 1 0 Rec10 / Red1 GREB1 PF15782.5 RUS92028.1 - 0.68 7.0 27.1 0.82 6.7 27.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 RUS92028.1 - 0.98 7.5 30.6 1.2 7.1 30.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.27 RUS92029.1 - 2e-26 92.9 0.0 3.7e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.6 RUS92029.1 - 1.2e-05 24.8 3.8 2.8e-05 23.6 3.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 RUS92029.1 - 0.00014 21.7 7.8 0.00014 21.7 7.8 1.8 2 0 0 2 2 2 1 PHD-finger Peptidase_C78 PF07910.13 RUS92030.1 - 5.3e-41 140.4 0.1 6.1e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 RUS92030.1 - 5.3e-05 22.8 0.1 0.13 11.6 0.2 2.2 2 0 0 2 2 2 2 Peptidase family C54 Yae1_N PF09811.9 RUS92031.1 - 1.7e-05 24.4 4.3 2.4e-05 23.9 4.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal E1_dh PF00676.20 RUS92032.1 - 3.3e-114 380.9 0.1 3.9e-114 380.6 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RUS92032.1 - 5.7e-05 22.4 0.5 0.0001 21.6 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RUS92032.1 - 0.00077 19.3 2.2 0.0012 18.6 0.5 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 RUS92033.1 - 1.1e-22 80.7 0.1 2.1e-22 79.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS92033.1 - 6.5e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RUS92033.1 - 7.5e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Vinculin PF01044.19 RUS92034.1 - 0.02 13.1 0.0 0.025 12.8 0.0 1.0 1 0 0 1 1 1 0 Vinculin family BLOC1S3 PF15753.5 RUS92035.1 - 9.7e-35 120.2 4.8 1.2e-34 120.0 4.8 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Maf PF02545.14 RUS92036.1 - 3.6e-53 179.8 0.0 4.2e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein PfkB PF00294.24 RUS92037.1 - 7.8e-29 100.9 0.0 9.6e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SYF2 PF08231.12 RUS92038.1 - 2.4e-52 177.5 14.2 2.4e-52 177.5 14.2 2.1 1 1 1 2 2 2 1 SYF2 splicing factor Conotoxin PF02950.17 RUS92038.1 - 1.5 9.9 4.1 3.2 8.9 2.7 2.3 1 1 1 2 2 2 0 Conotoxin Ribosomal_S30AE PF02482.19 RUS92038.1 - 6.4 7.6 11.8 0.76 10.6 1.0 3.7 3 2 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein DSL PF01414.19 RUS92039.1 - 5.7e-09 36.1 2.9 5.7e-09 36.1 2.9 3.0 2 1 0 2 2 2 1 Delta serrate ligand EGF_CA PF07645.15 RUS92039.1 - 4.7e-07 29.9 6.9 4.7e-07 29.9 6.9 3.6 3 1 1 4 4 4 2 Calcium-binding EGF domain hEGF PF12661.7 RUS92039.1 - 1.6e-05 25.3 22.0 0.00068 20.2 2.6 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF EGF PF00008.27 RUS92039.1 - 2.1e-05 24.7 25.3 0.005 17.1 6.1 3.4 3 0 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 RUS92039.1 - 0.0073 16.7 39.9 0.09 13.2 11.4 4.1 4 1 0 4 4 4 2 EGF-like domain RSN1_TM PF13967.6 RUS92039.1 - 0.025 14.3 0.3 0.048 13.4 0.3 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TMEM154 PF15102.6 RUS92039.1 - 0.096 12.6 0.1 0.41 10.5 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family PAP2_3 PF14378.6 RUS92039.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily EphA2_TM PF14575.6 RUS92039.1 - 0.13 13.2 0.0 0.42 11.5 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-lactamase PF00144.24 RUS92042.1 - 1.6e-31 109.8 0.0 2.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 RUS92042.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) SSF PF00474.17 RUS92043.1 - 8.2e-13 48.0 23.8 8.2e-12 44.7 15.9 2.4 2 0 0 2 2 2 2 Sodium:solute symporter family MARVEL PF01284.23 RUS92044.1 - 1.3e-07 31.8 9.2 1.4e-07 31.6 9.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ost5 PF05251.12 RUS92044.1 - 0.074 13.3 0.6 0.074 13.3 0.6 2.4 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 ERGIC_N PF13850.6 RUS92044.1 - 0.32 11.4 0.0 0.32 11.4 0.0 2.2 2 1 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF373 PF04123.13 RUS92044.1 - 0.35 10.3 5.4 0.44 9.9 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) OppC_N PF12911.7 RUS92044.1 - 1.3 9.1 4.0 5.3 7.1 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1153 PF06627.11 RUS92045.1 - 0.0073 16.4 9.1 19 5.5 0.2 5.5 2 2 3 6 6 6 1 Protein of unknown function (DUF1153) Baseplate PF16774.5 RUS92045.1 - 0.01 15.7 0.1 2.5 8.0 0.0 2.3 1 1 1 2 2 2 0 Baseplate protein CgtA PF06306.11 RUS92045.1 - 0.013 15.0 0.0 3.6 6.9 0.0 2.5 1 1 1 2 2 2 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) AbiTii PF18864.1 RUS92045.1 - 0.036 14.2 0.1 0.1 12.7 0.0 1.8 1 1 1 2 2 2 0 AbiTii UPF0728 PF15092.6 RUS92045.1 - 0.053 13.4 0.4 9.5 6.1 0.1 3.5 1 1 3 4 4 4 0 Uncharacterised protein family UPF0728 Pox_F12L PF03337.13 RUS92045.1 - 0.18 9.9 2.5 10 4.2 0.1 3.0 1 1 1 3 3 3 0 Poxvirus F12L protein MetJ PF01340.20 RUS92046.1 - 0.001 19.0 10.9 1.8 8.6 1.0 3.3 1 1 2 3 3 3 3 Met Apo-repressor, MetJ HTH_Tnp_1_2 PF13022.6 RUS92046.1 - 4 7.6 17.2 4.3 7.5 1.4 3.5 1 1 3 4 4 4 0 Helix-turn-helix of insertion element transposase SKI PF01202.22 RUS92046.1 - 5.4 7.1 14.4 35 4.5 6.0 2.6 1 1 1 2 2 2 0 Shikimate kinase IclR PF01614.18 RUS92046.1 - 5.7 6.8 24.4 5.9 6.7 2.2 3.9 1 1 3 4 4 4 0 Bacterial transcriptional regulator FliG_C PF01706.16 RUS92047.1 - 1.7e-06 28.1 0.8 8.2 6.7 0.0 4.8 1 1 5 6 6 6 6 FliG C-terminal domain Phasin_2 PF09361.10 RUS92047.1 - 3e-06 27.4 0.1 67 3.8 0.0 5.8 1 1 5 6 6 6 0 Phasin protein Nebulin PF00880.18 RUS92047.1 - 0.00013 21.8 0.4 1.6e+02 2.4 0.0 6.0 6 0 0 6 6 6 0 Nebulin repeat zf-HC5HC2H PF13771.6 RUS92047.1 - 0.011 16.0 45.7 1.6 9.1 2.8 6.8 1 1 6 7 7 7 0 PHD-like zinc-binding domain CFEM PF05730.11 RUS92047.1 - 0.065 13.3 26.8 26 5.0 0.3 6.2 6 0 0 6 6 6 0 CFEM domain zf-HC5HC2H_2 PF13832.6 RUS92047.1 - 0.092 12.9 40.5 4 7.6 1.9 6.5 1 1 5 6 6 6 0 PHD-zinc-finger like domain zf_PR_Knuckle PF18445.1 RUS92047.1 - 0.13 12.1 25.5 54 3.7 0.2 7.1 7 0 0 7 7 7 0 PR zinc knuckle motif DUF4787 PF16029.5 RUS92047.1 - 8.8 6.5 38.8 20 5.4 1.1 6.4 1 1 5 6 6 6 0 Domain of unknown function (DUF4787) DUF5437 PF17505.2 RUS92048.1 - 0.0007 19.6 11.0 76 3.4 0.0 6.5 7 0 0 7 7 7 6 Family of unknown function (DUF5437) DUF4573 PF15140.6 RUS92049.1 - 2.3e-13 50.3 1.5 2e-12 47.3 1.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) zf-C2H2_assoc2 PF16624.5 RUS92049.1 - 0.00059 20.8 1.9 6.1 7.9 0.1 3.1 1 1 2 3 3 3 2 Unstructured region upstream of a zinc-finger DUF3106 PF11304.8 RUS92049.1 - 0.0024 18.3 0.0 1.6 9.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3106) DUF3664 PF12406.8 RUS92049.1 - 0.015 15.9 14.8 4.1 8.1 1.0 3.4 1 1 2 3 3 3 0 Surface protein Paramecium_SA PF01508.16 RUS92049.1 - 0.12 12.8 27.9 1.8e+04 -11.7 27.9 4.4 1 1 0 1 1 1 0 Paramecium surface antigen domain RNA_pol_Rpb2_7 PF04560.20 RUS92049.1 - 0.57 10.6 20.4 31 5.1 1.8 4.7 1 1 2 3 3 3 0 RNA polymerase Rpb2, domain 7 Glyc_hyd_38C_2 PF18230.1 RUS92049.1 - 1.3 9.2 24.3 6.6 6.9 0.3 5.9 1 1 2 3 3 3 0 Glycosyl hydrolases family 38 C-terminal sub-domain YtkA PF13115.6 RUS92050.1 - 0.2 12.3 0.0 1.1e+02 3.5 0.0 4.2 2 2 1 6 6 6 0 YtkA-like Cbl_N3 PF02762.14 RUS92050.1 - 5.6 6.9 15.0 36 4.3 0.3 4.6 1 1 5 6 6 6 0 CBL proto-oncogene N-terminus, SH2-like domain Ephrin_rec_like PF07699.13 RUS92052.1 - 2.7 7.8 8.9 0.3 10.9 3.5 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like DNA_pol_B_exo1 PF03104.19 RUS92053.1 - 6.4e-26 91.3 0.7 8.8e-26 90.8 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 RUS92053.1 - 3.8e-09 35.8 0.0 6.6e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B RNase_H_2 PF13482.6 RUS92053.1 - 0.012 15.6 1.4 0.11 12.5 1.4 2.3 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 RUS92053.1 - 0.049 13.3 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 3'-5' exonuclease Rib PF08428.10 RUS92055.1 - 0.00068 19.6 0.0 13 5.9 0.1 4.4 1 1 2 3 3 3 2 Rib/alpha-like repeat Ribosomal_L22e PF01776.17 RUS92055.1 - 0.0012 19.2 0.3 0.19 12.1 0.0 2.8 1 1 1 3 3 3 1 Ribosomal L22e protein family FERM_M PF00373.18 RUS92055.1 - 0.13 12.7 6.0 12 6.3 0.1 4.1 1 1 4 5 5 5 0 FERM central domain MG1 PF17790.1 RUS92055.1 - 3.7 8.0 6.7 42 4.7 0.9 3.8 1 1 2 3 3 3 0 Macroglobulin domain MG1 BofC_C PF08955.10 RUS92055.1 - 3.7 7.7 8.1 62 3.7 0.1 4.1 1 1 5 6 6 6 0 BofC C-terminal domain Acyl_transf_1 PF00698.21 RUS92055.1 - 4.2 6.8 8.9 21 4.5 0.7 4.3 1 1 3 4 4 4 0 Acyl transferase domain VWA_N2 PF16164.5 RUS92055.1 - 4.6 7.5 9.0 55 4.0 1.4 4.4 2 1 2 4 4 4 0 VWA N-terminal DUF2272 PF10030.9 RUS92055.1 - 5.9 6.6 6.3 73 3.0 0.1 4.3 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2272) Cadherin PF00028.17 RUS92056.1 - 6.5e-91 299.0 0.0 6.5e-17 61.8 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 RUS92056.1 - 9.4e-15 54.2 0.0 3.6e-11 42.7 0.0 4.2 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 RUS92056.1 - 3e-05 24.0 0.1 0.42 10.6 0.1 5.2 6 0 0 6 6 6 1 Cadherin-like HNH PF01844.23 RUS92058.1 - 0.02 15.1 0.5 0.9 9.8 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease DUF4726 PF15855.5 RUS92058.1 - 1.1 9.5 4.9 11 6.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) WEMBL PF05701.11 RUS92059.1 - 4.4e-07 29.0 9.4 0.00037 19.3 2.1 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light ADIP PF11559.8 RUS92059.1 - 4.1e-06 26.9 10.3 0.0095 16.0 1.8 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding RNA_pol_I_A49 PF06870.12 RUS92059.1 - 6.4e-06 25.3 3.4 0.0028 16.6 0.4 2.0 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor Bacillus_HBL PF05791.11 RUS92059.1 - 8.6e-06 25.7 0.4 0.064 13.1 0.1 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.6 RUS92059.1 - 1.3e-05 24.7 6.7 0.028 13.8 0.1 3.5 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding MukF_M PF17192.4 RUS92059.1 - 0.00015 21.5 4.7 0.14 11.9 0.4 2.1 2 0 0 2 2 2 2 MukF middle domain Baculo_PEP_C PF04513.12 RUS92059.1 - 0.00031 20.8 5.2 0.032 14.3 0.6 2.8 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 RUS92059.1 - 0.00042 20.8 11.0 0.054 14.0 3.8 2.1 1 1 1 2 2 2 2 Fez1 SlyX PF04102.12 RUS92059.1 - 0.00077 20.0 4.5 0.69 10.6 0.4 2.7 2 0 0 2 2 2 2 SlyX Filament PF00038.21 RUS92059.1 - 0.00091 18.9 8.2 0.0064 16.1 1.4 2.1 1 1 1 2 2 2 2 Intermediate filament protein DUF4200 PF13863.6 RUS92059.1 - 0.0013 19.1 2.6 1.2 9.5 0.2 2.6 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) Lebercilin PF15619.6 RUS92059.1 - 0.0022 17.7 9.4 0.042 13.5 1.9 2.5 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease Homez PF11569.8 RUS92059.1 - 0.0023 17.4 0.3 2.8 7.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF4407 PF14362.6 RUS92059.1 - 0.0034 16.8 3.1 0.055 12.8 3.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Med9 PF07544.13 RUS92059.1 - 0.0035 17.4 3.9 2.1 8.5 0.4 3.1 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.11 RUS92059.1 - 0.0043 16.0 6.4 0.29 10.0 0.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF812) DUF724 PF05266.14 RUS92059.1 - 0.0068 16.2 5.9 0.6 9.9 0.9 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF724) NYD-SP28 PF14772.6 RUS92059.1 - 0.0083 16.2 2.5 2.8 8.0 0.2 2.5 2 1 0 2 2 2 1 Sperm tail SKA2 PF16740.5 RUS92059.1 - 0.01 15.6 3.9 0.83 9.5 0.2 2.3 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1542 PF07564.11 RUS92059.1 - 0.011 15.9 2.8 22 5.3 0.0 4.1 3 1 0 4 4 4 0 Domain of Unknown Function (DUF1542) PhaP_Bmeg PF09602.10 RUS92059.1 - 0.012 15.6 1.5 4.2 7.3 0.1 2.4 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4618 PF15397.6 RUS92059.1 - 0.016 14.7 5.4 1.3 8.4 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) BORCS8 PF10167.9 RUS92059.1 - 0.017 15.1 6.7 0.74 9.8 0.6 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 SmpB PF01668.18 RUS92059.1 - 0.017 15.0 0.1 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 SmpB protein AAA_5 PF07728.14 RUS92059.1 - 0.019 15.0 3.8 2.2 8.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) LPP PF04728.13 RUS92059.1 - 0.023 15.1 0.4 16 6.0 0.0 2.8 2 2 0 2 2 2 0 Lipoprotein leucine-zipper FliJ PF02050.16 RUS92059.1 - 0.026 14.7 7.3 1.1 9.5 1.0 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein TRAF_BIRC3_bd PF16673.5 RUS92059.1 - 0.03 14.1 3.6 3 7.7 0.3 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 RUS92059.1 - 0.031 13.2 9.4 0.1 11.5 2.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 RUS92059.1 - 0.032 14.2 6.4 5.1 7.2 1.0 3.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FH2 PF02181.23 RUS92059.1 - 0.035 13.2 5.2 1.4 7.9 1.8 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain UPF0242 PF06785.11 RUS92059.1 - 0.039 14.1 6.6 0.24 11.5 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1955 PF09205.10 RUS92059.1 - 0.041 13.6 0.8 6.2 6.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Golgin_A5 PF09787.9 RUS92059.1 - 0.041 13.3 8.9 0.24 10.8 9.0 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 Kre28 PF17097.5 RUS92059.1 - 0.042 12.8 4.6 1.5 7.7 0.5 2.2 1 1 0 2 2 2 0 Spindle pole body component USP8_interact PF08941.10 RUS92059.1 - 0.042 13.7 4.0 3.3 7.5 0.2 2.2 2 0 0 2 2 2 0 USP8 interacting GMC_oxred_C PF05199.13 RUS92059.1 - 0.043 14.3 2.2 6.6 7.3 0.1 2.2 1 1 0 2 2 2 0 GMC oxidoreductase HIP1_clath_bdg PF16515.5 RUS92059.1 - 0.044 14.4 10.4 1.1 9.9 1.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 RUS92059.1 - 0.046 13.8 5.4 1.7 8.8 0.5 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ATP-synt_E_2 PF08112.11 RUS92059.1 - 0.055 13.7 0.1 16 5.9 0.0 2.7 2 0 0 2 2 2 0 ATP synthase epsilon subunit Exonuc_VII_L PF02601.15 RUS92059.1 - 0.075 12.6 10.2 0.82 9.2 10.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit BLOC1S3 PF15753.5 RUS92059.1 - 0.097 12.8 6.4 2.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Tho2 PF11262.8 RUS92059.1 - 0.1 11.8 4.4 0.63 9.2 0.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PKcGMP_CC PF16808.5 RUS92059.1 - 0.1 12.4 10.2 49 3.9 0.0 5.1 6 0 0 6 6 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase P4Ha_N PF08336.11 RUS92059.1 - 0.11 12.5 6.2 3.5 7.7 0.4 2.7 4 0 0 4 4 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.15 RUS92059.1 - 0.11 12.3 3.7 6.8 6.5 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator Mt_ATP-synt_D PF05873.12 RUS92059.1 - 0.11 12.3 0.2 16 5.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DivIVA PF05103.13 RUS92059.1 - 0.15 12.2 3.9 6.9 6.8 0.4 2.3 2 0 0 2 2 2 0 DivIVA protein DUF5446 PF17522.2 RUS92059.1 - 0.15 12.2 3.3 16 5.8 0.1 3.1 2 1 1 3 3 2 0 Family of unknown function (DUF5446) DUF16 PF01519.16 RUS92059.1 - 0.18 12.3 4.1 8.3 7.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4140 PF13600.6 RUS92059.1 - 0.26 11.8 3.5 11 6.5 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2203 PF09969.9 RUS92059.1 - 0.4 11.4 5.1 5.6 7.7 0.6 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 RUS92059.1 - 0.44 11.0 6.6 7.1 7.2 0.8 2.5 2 0 0 2 2 2 0 Cell division protein ZapB T7SS_ESX_EspC PF10824.8 RUS92059.1 - 0.47 10.9 5.2 13 6.3 0.4 2.8 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm FAM184 PF15665.5 RUS92059.1 - 0.47 10.2 11.0 4.5 7.0 2.3 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF948 PF06103.11 RUS92059.1 - 0.53 10.6 8.8 14 6.0 1.4 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 RUS92059.1 - 0.69 10.9 7.5 6.4 7.7 1.1 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 RUS92059.1 - 0.85 9.7 8.0 7.5 6.6 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.16 RUS92059.1 - 1.1 9.5 6.2 15 5.8 0.4 3.0 1 1 1 2 2 2 0 Hr1 repeat ATG16 PF08614.11 RUS92059.1 - 1.2 9.3 12.2 6.2 7.0 2.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 RUS92059.1 - 2.4 7.8 7.9 1.8 8.2 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) YabA PF06156.13 RUS92059.1 - 3.4 8.4 6.4 32 5.2 0.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Microtub_bd PF16796.5 RUS92060.1 - 6e-21 74.9 0.0 6.4e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 RUS92060.1 - 2.5e-20 72.7 0.0 2.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain PIF1 PF05970.14 RUS92060.1 - 0.023 13.9 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 RUS92060.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NifW PF03206.14 RUS92061.1 - 8.3e-08 32.7 0.7 0.54 10.8 0.0 6.2 2 1 4 7 7 7 2 Nitrogen fixation protein NifW UNC119_bdg PF15435.6 RUS92061.1 - 0.00082 19.0 2.8 0.53 9.8 0.0 3.6 2 2 2 4 4 4 2 UNC119-binding protein C5orf30 homologue Minor_capsid_2 PF11114.8 RUS92061.1 - 0.0085 16.1 1.2 0.94 9.5 0.0 3.1 3 1 0 3 3 3 1 Minor capsid protein tRNA-Thr_ED PF08915.11 RUS92061.1 - 0.026 14.6 1.6 46 4.1 0.0 4.8 6 0 0 6 6 6 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF222 PF02720.17 RUS92061.1 - 0.097 12.1 1.5 48 3.3 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF222) ADAM17_MPD PF16698.5 RUS92061.1 - 0.58 10.6 12.0 64 4.0 0.1 6.5 8 0 0 8 8 8 0 Membrane-proximal domain, switch, for ADAM17 zf-H2C2_2 PF13465.6 RUS92062.1 - 2.3e-36 122.6 33.1 6.9e-07 29.4 0.3 8.4 8 1 0 8 8 8 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 RUS92062.1 - 1.2e-31 106.6 43.5 0.0015 19.2 0.1 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 RUS92062.1 - 5e-27 92.8 46.4 0.00014 22.1 1.6 8.6 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-met PF12874.7 RUS92062.1 - 3.5e-19 68.5 29.4 0.042 14.2 1.1 8.6 8 0 0 8 8 8 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RUS92062.1 - 4.5e-17 61.6 47.1 0.0028 17.6 1.8 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RUS92062.1 - 2e-14 53.4 12.9 0.71 10.2 0.0 8.3 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RUS92062.1 - 7e-05 22.5 42.0 0.00098 18.8 2.3 7.7 8 0 0 8 8 8 4 zinc-finger C2H2-type CpXC PF14353.6 RUS92062.1 - 0.0011 19.0 20.3 3.9 7.5 0.0 7.0 6 2 2 8 8 8 2 CpXC protein C1_1 PF00130.22 RUS92062.1 - 0.0026 17.6 20.7 2 8.4 1.2 5.3 3 1 2 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 RUS92062.1 - 0.0045 16.9 17.4 4.7 7.3 0.0 6.2 5 1 2 7 7 6 1 Adenylate kinase, active site lid zf_UBZ PF18439.1 RUS92062.1 - 0.0061 16.1 21.8 11 5.7 0.3 7.8 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 RUS92062.1 - 0.016 16.0 13.2 2.9 8.7 0.2 4.5 3 2 0 4 4 4 0 zinc-ribbon family PHD PF00628.29 RUS92062.1 - 0.039 13.9 0.3 0.039 13.9 0.3 5.3 4 2 0 4 4 4 0 PHD-finger GAGA PF09237.11 RUS92062.1 - 0.044 13.6 1.7 4.2 7.3 0.0 3.7 3 0 0 3 3 3 0 GAGA factor zf-C2H2_3rep PF18868.1 RUS92062.1 - 0.096 13.4 20.7 1.3 9.7 6.1 5.2 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 RUS92062.1 - 0.12 12.3 26.4 10 6.1 0.0 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 RUS92062.1 - 0.19 11.3 0.0 0.19 11.3 0.0 5.6 6 2 2 8 8 8 0 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 RUS92062.1 - 0.61 10.6 4.8 61 4.2 0.2 4.2 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain Actin_micro PF17003.5 RUS92062.1 - 0.77 8.9 3.7 50 2.9 3.2 3.5 1 1 0 1 1 1 0 Putative actin-like family Zn-ribbon_8 PF09723.10 RUS92062.1 - 2.4 8.4 26.3 3 8.1 2.5 5.6 5 2 0 5 5 5 0 Zinc ribbon domain zf-Di19 PF05605.12 RUS92062.1 - 2.4 8.5 26.5 1.2 9.5 1.0 5.0 3 2 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 RUS92062.1 - 2.5 8.4 16.3 2 8.7 0.4 4.1 3 1 1 5 5 5 0 zinc-finger-containing domain DUF2256 PF10013.9 RUS92062.1 - 2.7 8.2 0.0 2.7 8.2 0.0 7.0 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Renin_r PF07850.14 RUS92063.1 - 0.0076 16.8 1.1 3.4 8.3 0.0 3.5 1 1 2 3 3 3 3 Renin receptor-like protein DUF2807 PF10988.8 RUS92064.1 - 0.043 13.6 0.5 0.05 13.4 0.5 1.1 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF3979 PF13141.6 RUS92064.1 - 0.14 12.4 0.0 11 6.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) DUF2110 PF09883.9 RUS92064.1 - 0.19 11.3 8.6 2.3 7.8 0.9 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) DUF4402 PF14352.6 RUS92064.1 - 0.54 10.9 10.9 1.1 10.0 10.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) zf-ISL3 PF14690.6 RUS92064.1 - 1.2 9.9 3.3 1e+02 3.7 0.1 3.5 1 1 3 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 IF2_assoc PF08364.11 RUS92064.1 - 4.7 7.6 23.8 37 4.7 1.5 5.8 2 2 3 5 5 5 0 Bacterial translation initiation factor IF-2 associated region Sulfotransfer_1 PF00685.27 RUS92065.1 - 1.3e-11 44.5 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 RUS92065.1 - 4.4e-09 37.1 0.1 4.5e-07 30.5 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family Proteasome PF00227.26 RUS92066.1 - 5e-32 110.9 0.0 6e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Lectin_C PF00059.21 RUS92067.1 - 1.9e-13 51.1 0.7 3.8e-13 50.1 0.7 1.5 1 0 0 1 1 1 1 Lectin C-type domain FH2 PF02181.23 RUS92068.1 - 3.1e-108 362.2 16.7 3.1e-108 362.2 16.7 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RUS92068.1 - 1.1e-48 165.5 0.1 1.1e-48 165.5 0.1 3.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RUS92068.1 - 3.9e-33 114.6 0.2 3.9e-33 114.6 0.2 3.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Lzipper-MIP1 PF14389.6 RUS92068.1 - 0.31 11.4 13.7 4.5 7.6 0.4 4.8 3 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.12 RUS92068.1 - 3.7 7.6 20.2 1.2 9.1 4.3 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RUS92068.1 - 4.3 7.3 30.1 0.44 10.6 15.6 3.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arginase PF00491.21 RUS92069.1 - 7.9e-64 215.9 0.0 1.1e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family LRRCT PF01463.24 RUS92069.1 - 0.059 13.9 0.0 0.2 12.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain CENP-H PF05837.12 RUS92070.1 - 1.5e-12 47.9 3.6 1.5e-12 47.9 3.6 2.0 1 1 1 2 2 2 1 Centromere protein H (CENP-H) Spc24 PF08286.11 RUS92070.1 - 0.013 15.7 6.8 0.013 15.7 6.8 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1380 PF07128.12 RUS92070.1 - 0.029 14.6 0.1 0.06 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Baculo_LEF5 PF04838.12 RUS92070.1 - 0.092 12.8 2.6 0.14 12.2 2.6 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 UCH PF00443.29 RUS92071.1 - 3.1e-43 148.1 9.6 9.4e-43 146.6 5.4 3.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RUS92071.1 - 1.4e-24 87.3 7.7 8.6e-24 84.7 7.7 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 RUS92071.1 - 0.085 13.2 0.1 24 5.6 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Aha1_N PF09229.11 RUS92072.1 - 1.1e-36 126.1 6.1 2.2e-36 125.1 6.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 RUS92072.1 - 2.8e-19 69.6 0.0 2e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein ABC_membrane PF00664.23 RUS92073.1 - 1.3e-69 235.0 36.0 5.4e-41 141.1 8.8 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 RUS92073.1 - 1.4e-55 187.6 0.0 1.7e-29 103.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RUS92073.1 - 4.1e-08 32.9 7.5 0.14 11.6 0.0 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RUS92073.1 - 4.5e-07 30.0 0.3 0.047 13.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RUS92073.1 - 7.7e-07 29.2 0.4 0.16 11.7 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RUS92073.1 - 0.00054 19.9 0.4 0.13 12.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 RUS92073.1 - 0.0014 18.8 0.3 0.47 10.5 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 RUS92073.1 - 0.0061 17.0 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RUS92073.1 - 0.0076 16.0 5.9 0.28 11.0 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RUS92073.1 - 0.01 15.1 0.2 0.19 11.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 RUS92073.1 - 0.038 13.2 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 RUS92073.1 - 0.1 12.8 0.2 21 5.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 RUS92073.1 - 0.12 11.3 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 RUS92073.1 - 0.14 12.2 6.2 0.45 10.5 1.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 RUS92073.1 - 0.16 12.5 2.8 5 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 RUS92073.1 - 0.2 11.2 0.3 5.1 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF389 PF04087.14 RUS92073.1 - 0.64 10.0 4.4 2.7 8.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF389) Med9 PF07544.13 RUS92075.1 - 1.9e-05 24.7 0.7 1.9e-05 24.7 0.7 20.7 7 4 12 21 21 21 3 RNA polymerase II transcription mediator complex subunit 9 DUF3800 PF12686.7 RUS92075.1 - 7.4e-05 23.4 0.3 8.4 7.1 0.3 6.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) PACT_coil_coil PF10495.9 RUS92076.1 - 5.2e-20 71.8 0.0 5.2e-20 71.8 0.0 4.0 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF1664 PF07889.12 RUS92076.1 - 0.0031 17.5 1.0 0.0031 17.5 1.0 8.9 3 3 8 12 12 12 4 Protein of unknown function (DUF1664) HDOD PF08668.12 RUS92076.1 - 0.0079 15.7 0.5 5.8 6.3 0.1 2.9 2 0 0 2 2 2 2 HDOD domain DBD_Tnp_Mut PF03108.15 RUS92076.1 - 0.017 15.1 2.2 5 7.2 0.1 2.8 3 0 0 3 3 3 0 MuDR family transposase TolA_bind_tri PF16331.5 RUS92076.1 - 0.018 15.1 0.1 0.018 15.1 0.1 11.7 6 4 6 12 12 12 0 TolA binding protein trimerisation PBP5_C PF07943.13 RUS92076.1 - 0.45 10.8 3.0 24 5.2 0.1 2.8 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain Tryp_alpha_amyl PF00234.22 RUS92076.1 - 7 7.2 12.2 3.5 8.1 0.8 3.7 3 1 0 3 3 3 0 Protease inhibitor/seed storage/LTP family zf-RING_UBOX PF13445.6 RUS92077.1 - 1.3e-09 37.9 8.8 1.3e-09 37.9 8.8 2.8 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RUS92077.1 - 1.4e-09 37.7 7.5 1.4e-09 37.7 7.5 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RUS92077.1 - 3.8e-07 30.1 10.0 3.8e-07 30.1 10.0 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RUS92077.1 - 4.6e-07 30.1 7.8 4.6e-07 30.1 7.8 3.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 RUS92077.1 - 1.9e-06 27.6 5.9 1.9e-06 27.6 5.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS92077.1 - 2.2e-06 27.4 8.5 2.2e-06 27.4 8.5 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RUS92077.1 - 2.5e-05 24.1 6.5 2.5e-05 24.1 6.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain NHL PF01436.21 RUS92077.1 - 4.5e-05 23.3 0.6 13 6.0 0.0 4.9 6 0 0 6 6 5 0 NHL repeat Prok-RING_4 PF14447.6 RUS92077.1 - 0.00028 20.7 7.5 0.00028 20.7 7.5 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 UvrD_C PF13361.6 RUS92077.1 - 0.0016 17.9 0.5 0.0025 17.3 0.5 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Arylesterase PF01731.20 RUS92077.1 - 0.0022 18.1 0.1 0.47 10.7 0.1 2.5 2 0 0 2 2 2 1 Arylesterase zf-B_box PF00643.24 RUS92077.1 - 0.0023 18.0 1.3 0.0023 18.0 1.3 3.3 4 0 0 4 4 3 1 B-box zinc finger RNA_pol_Rpb2_4 PF04566.13 RUS92077.1 - 0.011 16.0 0.1 0.048 14.0 0.0 2.1 2 0 0 2 2 1 0 RNA polymerase Rpb2, domain 4 DUF5128 PF17170.4 RUS92077.1 - 0.037 13.2 0.3 0.078 12.1 0.0 1.6 2 0 0 2 2 2 0 6-bladed beta-propeller zf-Nse PF11789.8 RUS92077.1 - 0.049 13.5 5.3 0.17 11.7 5.3 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PLC-beta_C PF08703.10 RUS92077.1 - 0.056 13.4 4.4 0.1 12.6 4.4 1.3 1 0 0 1 1 1 0 PLC-beta C terminal DUF1724 PF08350.10 RUS92077.1 - 0.071 13.3 0.2 0.62 10.2 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF1724) FAD-SLDH PF12318.8 RUS92077.1 - 0.26 11.3 1.2 0.52 10.4 1.2 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4407 PF14362.6 RUS92077.1 - 0.69 9.2 7.0 0.97 8.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YkyA PF10368.9 RUS92077.1 - 0.76 9.4 10.4 1.2 8.8 10.4 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein NOA36 PF06524.12 RUS92077.1 - 1.1 8.5 10.6 2.1 7.6 0.5 2.6 2 1 0 2 2 2 0 NOA36 protein NYD-SP28 PF14772.6 RUS92077.1 - 1.8 8.7 6.3 1.9 8.6 4.4 1.9 1 1 1 2 2 2 0 Sperm tail zf-RING_10 PF16685.5 RUS92077.1 - 3 8.1 11.6 0.19 11.9 2.3 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 RUS92077.1 - 3.1 7.8 10.9 1.2 9.1 1.1 2.7 2 0 0 2 2 2 0 zinc-ribbons 7tm_1 PF00001.21 RUS92078.1 - 1.4e-43 149.1 20.6 2e-43 148.6 20.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS92078.1 - 2.7e-05 23.7 20.2 3.5e-05 23.3 20.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS92078.1 - 0.0068 16.2 14.7 0.24 11.1 14.7 2.2 1 1 0 1 1 1 1 Olfactory receptor eIF3m_C_helix PF18005.1 RUS92080.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF4203 PF13886.6 RUS92081.1 - 1.4e-36 126.1 27.5 1.7e-36 125.8 27.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TRIQK PF15168.6 RUS92081.1 - 0.047 13.6 0.1 0.047 13.6 0.1 2.5 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF4231 PF14015.6 RUS92081.1 - 2.8 8.5 5.8 5.2 7.6 1.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) C2-set_2 PF08205.12 RUS92082.1 - 0.028 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF1682 PF07946.14 RUS92083.1 - 1.2e-97 327.0 7.8 1.6e-97 326.6 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) F-box-like PF12937.7 RUS92085.1 - 6.7e-10 38.7 2.4 6.7e-10 38.7 2.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 RUS92085.1 - 1.2e-06 28.2 3.2 1.5e-06 27.9 0.8 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 RUS92085.1 - 1.6e-05 25.1 5.4 0.00082 19.7 0.2 4.4 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 RUS92085.1 - 2.3e-05 24.3 0.1 4.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 RUS92085.1 - 0.0014 18.3 0.5 0.0014 18.3 0.5 3.8 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 RUS92085.1 - 9 6.6 13.8 4.6 7.5 0.1 5.7 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.7 RUS92086.1 - 0.0017 18.7 0.0 1.7 9.2 0.0 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RUS92086.1 - 0.099 12.4 0.0 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Leucine rich repeat OB_NTP_bind PF07717.16 RUS92088.1 - 6.7e-11 42.4 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold zf-C2H2_4 PF13894.6 RUS92088.1 - 0.24 12.3 1.3 1.3 10.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 RUS92088.1 - 0.3 11.0 2.0 8.8 6.3 0.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain RSRP PF17069.5 RUS92089.1 - 4.7 6.7 30.3 7.3 6.1 30.3 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Nucleoplasmin PF03066.15 RUS92090.1 - 1.5e-16 60.7 0.0 1.5e-16 60.7 0.0 2.6 3 0 0 3 3 3 1 Nucleoplasmin/nucleophosmin domain NPL PF17800.1 RUS92090.1 - 0.0091 16.5 0.0 0.0091 16.5 0.0 3.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain Na_trans_assoc PF06512.13 RUS92090.1 - 0.69 10.2 24.6 0.15 12.3 18.9 2.1 1 1 1 2 2 2 0 Sodium ion transport-associated BUD22 PF09073.10 RUS92090.1 - 1.4 8.2 43.7 0.069 12.5 38.0 1.6 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 RUS92090.1 - 1.7 8.0 52.3 0.011 15.2 43.9 1.5 2 0 0 2 2 2 0 SDA1 FGF PF00167.18 RUS92091.1 - 9e-11 42.0 0.1 3e-10 40.3 0.1 1.9 1 0 0 1 1 1 1 Fibroblast growth factor Exo_endo_phos_2 PF14529.6 RUS92092.1 - 0.00049 19.9 1.0 0.075 12.9 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 RUS92092.1 - 0.072 12.6 0.0 0.22 11.0 0.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Atg14 PF10186.9 RUS92092.1 - 2.4 7.2 19.3 0.26 10.3 14.9 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sulfotransfer_4 PF17784.1 RUS92092.1 - 5 6.9 8.4 2.6 7.8 4.6 2.1 2 1 0 2 2 2 0 Sulfotransferase domain DUF974 PF06159.13 RUS92093.1 - 5.6e-83 278.5 0.0 8.1e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RUS92093.1 - 0.018 14.5 0.0 4.6 6.6 0.0 3.1 3 0 0 3 3 3 0 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 RUS92093.1 - 0.069 13.3 0.0 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain SBF PF01758.16 RUS92094.1 - 2.3e-18 66.6 1.8 2.3e-18 66.6 1.8 2.2 1 1 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 RUS92094.1 - 5.9e-07 29.1 12.0 9.7e-07 28.4 11.6 1.4 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) JAB PF01398.21 RUS92095.1 - 3.3e-17 62.6 0.3 7.6e-17 61.4 0.3 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_1 PF00515.28 RUS92096.1 - 3.7e-28 96.2 10.4 9.6e-11 41.0 0.5 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 RUS92096.1 - 2.3e-17 62.5 3.4 1.1e-15 57.2 0.6 2.4 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 RUS92096.1 - 4e-17 60.9 11.7 1.5e-07 31.0 0.5 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RUS92096.1 - 1.1e-15 57.0 9.5 2.3e-07 30.4 0.2 4.0 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 RUS92096.1 - 2.9e-14 52.0 7.6 2.2e-07 30.5 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RUS92096.1 - 4.9e-11 41.8 3.8 0.00016 21.5 0.4 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RUS92096.1 - 4.5e-10 39.2 6.2 0.00051 20.2 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RUS92096.1 - 2.9e-08 34.2 0.7 0.0016 19.1 0.1 2.9 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RUS92096.1 - 7.4e-08 32.6 0.3 0.00022 21.8 0.1 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 RUS92096.1 - 4.4e-07 30.1 5.1 6e-05 23.3 1.7 3.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RUS92096.1 - 8.8e-06 26.1 7.8 9.1e-05 22.9 0.3 3.4 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 RUS92096.1 - 0.00023 20.5 0.2 0.58 9.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.12 RUS92096.1 - 0.00029 20.6 0.4 0.0029 17.4 0.1 2.7 2 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_9 PF13371.6 RUS92096.1 - 0.0011 19.0 0.2 0.0061 16.7 0.1 2.3 2 1 0 2 2 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RUS92096.1 - 0.0041 17.2 3.2 0.36 10.9 0.8 3.2 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RUS92096.1 - 0.005 16.7 5.3 0.75 9.8 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RUS92096.1 - 0.016 15.8 1.4 3.1 8.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 RUS92096.1 - 0.033 14.3 8.7 1.6 8.9 0.4 3.9 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 RUS92096.1 - 0.058 13.8 1.1 0.29 11.6 0.4 2.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain COMP PF11598.8 RUS92096.1 - 0.081 13.4 1.3 0.081 13.4 1.3 1.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein STI1 PF17830.1 RUS92096.1 - 2 8.4 9.4 0.37 10.8 0.5 3.3 3 0 0 3 3 3 0 STI1 domain Pkinase PF00069.25 RUS92097.1 - 6e-45 153.7 0.0 9.6e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RUS92097.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTEN_C2 PF10409.9 RUS92097.1 - 3.6e-20 72.1 0.0 6.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Haspin_kinase PF12330.8 RUS92097.1 - 3.1e-06 26.4 0.5 1e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 RUS92097.1 - 3.7e-05 23.2 0.1 0.0047 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DnaJ PF00226.31 RUS92097.1 - 6.1e-05 23.1 0.0 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain DSPc PF00782.20 RUS92097.1 - 0.0057 16.5 0.2 0.014 15.2 0.2 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain APH PF01636.23 RUS92097.1 - 0.012 15.5 0.0 0.75 9.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Init_tRNA_PT PF04179.12 RUS92097.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain HAUS-augmin3 PF14932.6 RUS92098.1 - 2.1e-39 135.7 8.6 2.1e-39 135.7 8.6 2.8 2 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 FtsA PF14450.6 RUS92098.1 - 0.19 12.2 3.2 9.1 6.8 0.2 3.1 2 1 0 2 2 2 0 Cell division protein FtsA FlaC_arch PF05377.11 RUS92098.1 - 2.1 8.8 10.9 11 6.5 0.5 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 RUS92098.1 - 3.1 7.9 7.8 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Phageshock_PspG PF09583.10 RUS92099.1 - 0.3 11.4 17.1 8.4 6.8 3.3 4.1 1 1 3 4 4 4 0 Phage shock protein G (Phageshock_PspG) PsbN PF02468.15 RUS92099.1 - 1.9 8.4 24.7 6 6.8 0.6 5.8 1 1 6 7 7 7 0 Photosystem II reaction centre N protein (psbN) UPF0004 PF00919.20 RUS92100.1 - 1.6e-20 72.9 0.0 4.6e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 RUS92100.1 - 1e-17 65.0 0.0 3.1e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TraT PF05818.12 RUS92100.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DNA_pol_lambd_f PF10391.9 RUS92100.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Ion_trans PF00520.31 RUS92101.1 - 1.4e-50 171.8 4.6 1.9e-50 171.4 4.6 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 RUS92101.1 - 2.9e-31 107.7 0.0 6.2e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 RUS92101.1 - 1.5e-12 47.3 2.1 1.5e-12 47.3 2.1 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RUS92101.1 - 0.00035 19.4 0.4 0.00055 18.7 0.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel BTB_3 PF16017.5 RUS92101.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Brix PF04427.18 RUS92103.1 - 3.3e-26 92.6 0.4 3.3e-26 92.6 0.4 1.8 2 0 0 2 2 2 1 Brix domain RibD_C PF01872.17 RUS92103.1 - 0.19 11.6 0.3 0.34 10.7 0.3 1.4 1 0 0 1 1 1 0 RibD C-terminal domain PI3K_P85_iSH2 PF16454.5 RUS92104.1 - 4.6e-33 114.1 14.2 8e-33 113.3 14.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 RUS92104.1 - 5.2e-31 106.6 0.0 2.6e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 RUS92104.1 - 1.4e-27 96.4 0.0 4.7e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 RUS92104.1 - 2.1e-18 65.9 30.2 9.6e-10 38.2 14.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_1 PF00536.30 RUS92104.1 - 6.1e-12 45.8 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RUS92104.1 - 4.4e-09 36.3 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 RUS92104.1 - 0.012 15.2 0.1 0.096 12.3 0.1 2.4 1 1 0 1 1 1 0 SH3 domain DUF285 PF03382.14 RUS92104.1 - 0.052 13.3 0.3 6.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Mycoplasma protein of unknown function, DUF285 DUF4200 PF13863.6 RUS92104.1 - 0.072 13.5 4.5 0.15 12.4 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-RING_9 PF13901.6 RUS92104.1 - 4.9 7.1 23.6 7.7 6.4 6.5 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Tup_N PF08581.10 RUS92104.1 - 6 7.2 7.7 0.16 12.2 0.6 2.1 2 0 0 2 2 2 0 Tup N-terminal DUF389 PF04087.14 RUS92106.1 - 1.1e-42 145.4 6.9 1.8e-42 144.8 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) muHD PF10291.9 RUS92107.1 - 9.5e-49 166.2 0.0 1.6e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 RUS92107.1 - 5.3e-10 39.5 0.8 1.8e-09 37.7 0.0 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain STAT_alpha PF01017.20 RUS92107.1 - 0.088 12.7 5.2 0.12 12.2 4.1 1.8 1 1 0 1 1 1 0 STAT protein, all-alpha domain Pox_F11 PF04943.12 RUS92107.1 - 0.18 10.9 0.9 0.27 10.3 0.9 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein P4Ha_N PF08336.11 RUS92107.1 - 1.4 8.9 6.2 9.6 6.2 0.1 2.7 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Utp21 PF04192.12 RUS92108.1 - 8.2e-68 228.4 2.0 1.2e-67 227.8 2.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 RUS92108.1 - 5.6e-20 71.3 25.9 4.8e-06 27.2 0.2 10.4 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RUS92108.1 - 2.9e-15 56.3 0.3 8.4e-05 22.8 0.0 6.8 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RUS92108.1 - 4.2e-05 23.0 0.1 0.0093 15.3 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain Utp12 PF04003.12 RUS92108.1 - 0.00036 20.8 0.4 0.00082 19.7 0.4 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family BBS2_Mid PF14783.6 RUS92108.1 - 0.0014 18.7 0.0 0.85 9.7 0.0 4.1 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 RUS92108.1 - 0.022 13.3 0.1 0.041 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain G2F PF07474.12 RUS92108.1 - 0.05 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 G2F domain XRCC1_N PF01834.16 RUS92110.1 - 4.7e-07 29.9 0.0 6.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 XRCC1 N terminal domain F5_F8_type_C PF00754.25 RUS92110.1 - 4.7e-06 26.7 0.0 8.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 RUS92110.1 - 0.0027 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF3999 PF13163.6 RUS92110.1 - 0.078 12.2 0.0 0.16 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) Palm_thioest PF02089.15 RUS92111.1 - 1.9e-83 280.1 0.1 2.1e-83 279.9 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RUS92111.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FlgT_C PF16538.5 RUS92112.1 - 0.19 12.3 2.7 3.3 8.3 0.3 3.4 3 0 0 3 3 3 0 Flagellar assembly protein T, C-terminal domain SWIRM PF04433.17 RUS92112.1 - 1.5 9.2 6.5 0.35 11.2 0.5 3.1 2 0 0 2 2 2 0 SWIRM domain Baculo_PEP_C PF04513.12 RUS92112.1 - 3.8 7.6 35.2 0.23 11.5 0.8 6.0 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus ASXH PF13919.6 RUS92113.1 - 1.6e-36 125.4 1.7 3.7e-36 124.2 1.1 2.0 2 0 0 2 2 2 1 Asx homology domain GSHPx PF00255.19 RUS92114.1 - 4.1e-32 110.0 0.0 6.9e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RUS92114.1 - 0.00047 20.1 0.0 0.0009 19.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family HMG_CoA_synt_C PF08540.10 RUS92115.1 - 1.1e-108 363.1 0.2 1.4e-108 362.8 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 RUS92115.1 - 4.4e-99 329.5 0.9 6.6e-99 328.9 0.9 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal LURAP PF14854.6 RUS92115.1 - 0.077 12.9 0.8 0.24 11.4 0.8 1.8 1 0 0 1 1 1 0 Leucine rich adaptor protein ACP_syn_III_C PF08541.10 RUS92115.1 - 0.11 12.7 0.1 0.43 10.8 0.1 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.25 RUS92116.1 - 9.4e-35 119.8 0.1 1.3e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS92116.1 - 2.4e-30 105.8 0.2 3.4e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RUS92116.1 - 4.7e-05 23.4 0.4 6.9e-05 22.8 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 RUS92116.1 - 0.056 14.1 0.1 0.43 11.3 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain adh_short PF00106.25 RUS92117.1 - 2.4e-31 108.7 0.0 3.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RUS92117.1 - 4e-29 101.8 0.1 6.2e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 RUS92117.1 - 2.2e-24 85.9 0.3 4.5e-24 84.9 0.3 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RUS92117.1 - 0.00018 21.8 0.1 0.00034 20.9 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal KR PF08659.10 RUS92117.1 - 0.00033 20.6 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 RUS92117.1 - 0.0031 18.2 0.3 0.77 10.4 0.1 2.4 1 1 1 2 2 2 2 Homoserine dehydrogenase, NAD binding domain TF_AP-2 PF03299.14 RUS92119.1 - 0.0091 16.0 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 Transcription factor AP-2 GTP_cyclohydro2 PF00925.20 RUS92119.1 - 0.048 13.2 0.4 0.069 12.7 0.4 1.4 1 1 0 1 1 1 0 GTP cyclohydrolase II Dimer_Tnp_hAT PF05699.14 RUS92119.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Amidase PF01425.21 RUS92120.1 - 5.4e-21 75.1 0.0 6.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Spectrin PF00435.21 RUS92121.1 - 3.7e-68 226.6 39.0 3.4e-14 53.2 0.1 8.0 8 0 0 8 8 8 7 Spectrin repeat GAS2 PF02187.17 RUS92121.1 - 1.1e-32 111.9 0.6 1.1e-32 111.9 0.6 2.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.32 RUS92121.1 - 1.1e-10 40.3 6.3 5.2e-06 25.6 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 RUS92121.1 - 3.7e-10 38.9 2.6 0.00017 21.3 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RUS92121.1 - 2.1e-08 34.5 3.4 2.7e-08 34.1 0.8 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 RUS92121.1 - 3.5e-07 30.0 3.6 2.3e-06 27.3 0.6 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RUS92121.1 - 3.2e-06 26.4 4.0 0.037 13.5 0.6 2.9 2 0 0 2 2 2 2 EF hand zf-ZPR1 PF03367.13 RUS92121.1 - 5.8 6.7 8.0 1.7 8.5 0.4 3.1 3 0 0 3 3 3 0 ZPR1 zinc-finger domain Mating_N PF12731.7 RUS92121.1 - 7.6 6.7 8.7 29 4.8 0.1 4.6 5 1 1 6 6 6 0 Mating-type protein beta 1 DUF167 PF02594.16 RUS92122.1 - 2.3e-17 62.9 0.0 3.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RNase_II_C_S1 PF18614.1 RUS92122.1 - 0.042 13.8 0.2 0.074 13.0 0.2 1.4 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain FAST_2 PF08368.12 RUS92123.1 - 1.9e-07 31.8 0.0 6.4e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 RUS92123.1 - 0.1 12.6 0.1 4.1 7.4 0.0 3.4 2 2 2 4 4 4 0 FAST kinase-like protein, subdomain 1 ig PF00047.25 RUS92124.1 - 2.3e-05 24.5 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS92124.1 - 0.00015 21.9 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 RUS92124.1 - 0.00042 19.8 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 RUS92124.1 - 0.0008 19.4 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS92124.1 - 0.0015 19.1 1.3 0.0038 17.8 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain CobT PF06213.12 RUS92124.1 - 0.0068 15.8 16.0 0.011 15.2 16.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT SAPS PF04499.15 RUS92124.1 - 0.0073 15.1 5.3 0.007 15.2 5.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Ig_2 PF13895.6 RUS92124.1 - 0.021 15.2 0.1 0.041 14.2 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Striatin PF08232.12 RUS92124.1 - 0.037 14.6 0.3 0.07 13.7 0.3 1.4 1 0 0 1 1 1 0 Striatin family V_ATPase_I PF01496.19 RUS92124.1 - 0.049 11.6 0.1 0.062 11.2 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 RUS92124.1 - 0.057 12.4 1.0 0.086 11.8 1.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 RUS92124.1 - 0.069 14.1 0.1 0.14 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DNA_pol_phi PF04931.13 RUS92124.1 - 0.17 9.9 49.7 0.22 9.6 49.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 RUS92124.1 - 0.18 12.3 17.2 0.37 11.3 17.2 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Serinc PF03348.15 RUS92124.1 - 0.19 10.6 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CNDH2_C PF16858.5 RUS92124.1 - 0.57 10.0 12.9 0.82 9.5 12.9 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2722 PF10846.8 RUS92124.1 - 1.9 7.3 21.1 3.2 6.6 21.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIIAH PF12685.7 RUS92124.1 - 5 6.9 12.3 8.4 6.2 12.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 RUS92124.1 - 8.3 4.5 38.7 11 4.1 38.7 1.1 1 0 0 1 1 1 0 Nop14-like family I-set PF07679.16 RUS92125.1 - 0.00084 19.4 0.0 0.00099 19.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 RUS92125.1 - 0.0048 17.5 0.0 0.0063 17.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 RUS92125.1 - 0.044 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF3039 PF11238.8 RUS92126.1 - 0.91 9.3 61.9 7.3 6.4 0.2 11.9 1 1 9 10 10 10 0 Protein of unknown function (DUF3039) DUF4817 PF16087.5 RUS92127.1 - 0.004 16.9 0.2 2.1e+02 1.8 0.0 5.0 3 1 6 9 9 9 0 Helix-turn-helix domain (DUF4817) PT PF04886.12 RUS92128.1 - 1.1e-08 34.4 83.7 1.8e+04 -50.1 83.7 5.1 1 1 0 1 1 1 0 PT repeat DUF966 PF06136.13 RUS92128.1 - 0.18 11.5 9.3 0.22 11.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.13 RUS92128.1 - 0.28 11.2 24.1 0.34 10.9 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-4B PF06273.11 RUS92128.1 - 0.8 8.7 20.4 2.4 7.1 2.2 3.9 1 1 2 3 3 3 0 Plant specific eukaryotic initiation factor 4B LAP1C PF05609.12 RUS92128.1 - 1.6 7.7 15.2 2 7.4 15.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sel1 PF08238.12 RUS92129.1 - 0.0039 17.8 0.0 0.012 16.3 0.0 1.9 1 0 0 1 1 1 1 Sel1 repeat Minor_capsid_3 PF12691.7 RUS92129.1 - 0.15 12.4 0.2 0.34 11.3 0.2 1.5 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Coilin_N PF15862.5 RUS92130.1 - 0.00038 20.3 8.4 0.00063 19.6 8.4 1.6 1 1 0 1 1 1 1 Coilin N-terminus AAA_23 PF13476.6 RUS92130.1 - 0.0017 18.9 10.8 0.002 18.7 10.8 1.1 1 0 0 1 1 1 1 AAA domain PRKCSH-like PF12999.7 RUS92130.1 - 0.047 13.5 8.3 0.064 13.0 8.3 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF1682 PF07946.14 RUS92130.1 - 0.23 10.6 18.8 0.28 10.3 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 RUS92130.1 - 0.58 9.9 7.9 0.64 9.7 7.9 1.2 1 0 0 1 1 1 0 Connexin Ureide_permease PF07168.11 RUS92130.1 - 1.2 7.8 3.2 1.6 7.4 3.2 1.2 1 0 0 1 1 1 0 Ureide permease 7tm_1 PF00001.21 RUS92131.1 - 1.1e-17 64.2 8.0 1.1e-17 64.2 8.0 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) ubiquitin PF00240.23 RUS92132.1 - 5e-19 67.8 0.9 7.5e-19 67.3 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 RUS92132.1 - 2.8e-08 33.6 76.2 0.0014 18.5 9.9 8.3 3 2 4 7 7 7 5 STI1 domain UBA PF00627.31 RUS92132.1 - 5.9e-08 32.5 0.3 2.5e-07 30.5 0.3 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 RUS92132.1 - 1.6e-06 27.8 0.6 2.7e-06 27.1 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 RUS92132.1 - 1.7e-05 25.1 0.5 3.5e-05 24.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain HOIP-UBA PF16678.5 RUS92132.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_4 PF18036.1 RUS92132.1 - 0.087 12.9 0.5 7.4 6.7 0.1 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain CLP1_P PF16575.5 RUS92133.1 - 3.1e-69 232.6 0.0 4.8e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 RUS92133.1 - 1.4e-33 115.0 0.6 2.2e-33 114.3 0.6 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 RUS92133.1 - 2.9e-31 108.3 0.4 4.9e-31 107.6 0.4 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 RUS92133.1 - 0.0013 18.8 0.0 0.0069 16.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 RUS92133.1 - 0.047 13.1 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 RUS92133.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RUS92133.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RUS92133.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CTV_P13 PF06922.11 RUS92133.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein AAA_18 PF13238.6 RUS92133.1 - 0.12 12.9 0.5 0.22 12.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain FANCI_HD2 PF14680.6 RUS92134.1 - 8.7e-56 188.8 13.6 6.5e-53 179.4 2.0 3.2 3 0 0 3 3 3 2 FANCI helical domain 2 FANCI_S4 PF14678.6 RUS92134.1 - 2.1e-54 184.3 0.5 2.1e-54 184.3 0.5 3.1 3 0 0 3 3 3 1 FANCI solenoid 4 FANCI_S1 PF14675.6 RUS92134.1 - 3.2e-53 180.6 2.9 1.1e-52 178.8 0.0 2.6 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_S2 PF14676.6 RUS92134.1 - 4.3e-40 137.7 1.5 3.3e-39 134.8 0.0 3.3 2 1 1 3 3 3 1 FANCI solenoid 2 FANCI_S3 PF14677.6 RUS92134.1 - 3.1e-30 105.5 3.7 3.1e-30 105.5 3.7 2.9 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_HD1 PF14679.6 RUS92134.1 - 3.4e-21 75.0 0.3 1.4e-20 73.0 0.3 2.2 1 0 0 1 1 1 1 FANCI helical domain 1 RIX1 PF08167.12 RUS92134.1 - 0.025 14.3 5.0 0.17 11.6 0.2 3.5 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Nsp1_C PF05064.13 RUS92136.1 - 0.0074 16.1 8.2 0.012 15.4 2.3 2.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region SlyX PF04102.12 RUS92136.1 - 0.43 11.2 8.0 10 6.8 1.1 3.7 2 1 1 3 3 3 0 SlyX DcrB PF08786.11 RUS92136.1 - 0.56 10.3 6.8 4.3 7.4 0.6 2.8 1 1 1 2 2 2 0 DcrB BRE1 PF08647.11 RUS92136.1 - 3 8.0 17.4 12 6.0 0.9 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pro_isomerase PF00160.21 RUS92137.1 - 1e-42 146.1 0.8 1.2e-42 145.8 0.8 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Imm9 PF15587.6 RUS92139.1 - 0.017 14.8 6.8 10 5.8 0.8 3.9 1 1 2 3 3 3 0 Immunity protein 9 SPRY PF00622.28 RUS92139.1 - 0.056 13.6 0.0 27 4.9 0.0 3.8 1 1 1 2 2 2 0 SPRY domain CsrA PF02599.16 RUS92139.1 - 0.1 12.5 6.4 32 4.6 6.1 2.8 1 1 0 1 1 1 0 Global regulator protein family VCX_VCY PF15231.6 RUS92141.1 - 0.00031 21.4 0.4 0.057 14.1 0.1 2.1 1 1 1 2 2 2 2 Variable charge X/Y family CTD PF12815.7 RUS92141.1 - 0.0015 19.1 18.5 0.6 10.7 18.2 2.4 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 PMG PF05287.12 RUS92141.1 - 0.1 12.6 32.9 0.32 11.0 12.6 2.1 1 1 1 2 2 2 0 PMG protein Lectin_C PF00059.21 RUS92142.1 - 2.7e-08 34.5 1.5 2.7e-08 34.5 1.5 1.6 2 0 0 2 2 2 1 Lectin C-type domain Adeno_E3_CR1 PF02440.15 RUS92142.1 - 0.024 14.4 0.3 0.043 13.6 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 DDE_Tnp_IS1595 PF12762.7 RUS92143.1 - 6.3e-08 32.8 0.1 1.3e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 ISXO2-like transposase domain OAD_gamma PF04277.13 RUS92144.1 - 0.095 13.3 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1180 PF06679.12 RUS92144.1 - 0.098 13.1 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DEFB136 PF17333.2 RUS92144.1 - 0.41 10.6 10.7 1.2 9.2 1.8 2.3 2 0 0 2 2 2 0 Beta defensin 136 7tm_1 PF00001.21 RUS92145.1 - 2.4e-79 266.4 0.1 7.1e-79 264.8 0.1 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 RUS92145.1 - 3.7e-10 39.6 8.3 7.7e-06 25.5 8.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 RUS92145.1 - 0.028 14.2 12.3 0.47 10.1 7.5 2.9 3 0 0 3 3 3 0 Olfactory receptor DUF2207 PF09972.9 RUS92145.1 - 0.69 8.6 5.4 7.4 5.2 0.6 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF445 PF04286.12 RUS92147.1 - 4.6e-09 36.6 8.4 2.2e-05 24.4 1.7 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF445) PGDH_C PF16896.5 RUS92147.1 - 1.1e-05 25.4 18.0 4.4 7.2 0.1 6.8 2 2 3 5 5 5 3 Phosphogluconate dehydrogenase (decarboxylating) C-term Sec15 PF04091.12 RUS92147.1 - 2.7e-05 23.7 20.3 1.5 8.2 0.3 5.9 2 2 2 4 4 4 3 Exocyst complex subunit Sec15-like Trigger_N PF05697.13 RUS92147.1 - 0.0096 16.3 8.3 22 5.4 1.3 5.9 1 1 0 2 2 2 0 Bacterial trigger factor protein (TF) SAC3 PF12209.8 RUS92147.1 - 0.014 15.6 3.3 18 5.6 0.1 5.1 2 2 1 4 4 4 0 Leucine permease transcriptional regulator helical domain AvrM-A PF18241.1 RUS92147.1 - 0.17 12.3 1.1 19 5.7 0.1 2.5 2 0 0 2 2 2 0 Flax-rust effector AvrM-A AAA_15 PF13175.6 RUS92147.1 - 0.28 10.9 14.5 7e+02 -0.3 14.5 2.5 1 1 0 1 1 1 0 AAA ATPase domain SecD_SecF PF02355.16 RUS92147.1 - 0.31 10.4 13.1 30 3.9 2.0 5.4 2 2 3 5 5 5 0 Protein export membrane protein DUF3819 PF12842.7 RUS92147.1 - 0.65 9.9 7.5 17 5.3 1.5 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3819) FAD-oxidase_C PF02913.19 RUS92148.1 - 1.9e-56 191.5 0.0 2.2e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RUS92148.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aa_trans PF01490.18 RUS92149.1 - 4.1e-55 187.1 18.7 4.7e-55 187.0 18.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 RUS92149.1 - 0.0056 15.6 0.3 0.0056 15.6 0.3 2.9 1 1 2 3 3 3 1 Spore germination protein GPHR_N PF12537.8 RUS92149.1 - 0.035 14.2 0.2 0.079 13.1 0.2 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF2730 PF10805.8 RUS92150.1 - 0.22 11.6 3.6 0.41 10.8 1.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) SOCS PF12610.8 RUS92150.1 - 3.9 7.9 8.2 1.2 9.5 1.1 2.9 3 0 0 3 3 3 0 Suppressor of cytokine signalling Snf7 PF03357.21 RUS92151.1 - 5.7e-46 156.3 28.8 5.7e-46 156.3 28.8 1.4 2 0 0 2 2 2 1 Snf7 FapA PF03961.13 RUS92151.1 - 1.8 7.1 12.8 2.5 6.6 12.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2229 PF09989.9 RUS92151.1 - 4.2 7.0 10.1 0.5 10.0 2.0 2.2 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) CSD PF00313.22 RUS92152.1 - 2.3e-66 219.5 20.5 7.4e-15 54.6 0.2 9.2 9 0 0 9 9 9 6 'Cold-shock' DNA-binding domain S1-like PF14444.6 RUS92152.1 - 1.1e-14 54.1 6.7 0.0015 18.4 0.1 7.0 7 1 0 7 7 7 5 S1-like SUZ-C PF12901.7 RUS92152.1 - 0.0048 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 SUZ-C motif Tcp11 PF05794.13 RUS92153.1 - 3.2e-100 336.3 0.8 3.7e-100 336.1 0.8 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1825 PF08855.10 RUS92153.1 - 0.0011 18.8 0.6 0.0049 16.8 0.6 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) WD40 PF00400.32 RUS92154.1 - 1.1e-39 133.7 24.5 6.3e-07 30.0 0.8 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 RUS92154.1 - 2.5e-12 46.5 0.1 6.4e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 RUS92154.1 - 3.7e-09 36.7 6.0 0.0004 20.6 0.2 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 RUS92154.1 - 1.7e-07 30.9 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 RUS92154.1 - 6.5e-06 25.7 0.0 0.0039 16.6 0.1 2.2 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 RUS92154.1 - 3e-05 22.9 4.6 4.8 5.7 0.0 5.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RUS92154.1 - 0.024 13.4 1.2 2 7.1 0.0 3.2 3 1 0 3 3 3 0 Nup133 N terminal like DUF4508 PF14969.6 RUS92154.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Elongin_A PF06881.11 RUS92154.1 - 0.12 12.9 3.5 0.25 11.9 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PALB2_WD40 PF16756.5 RUS92154.1 - 0.5 9.2 4.2 27 3.5 0.2 3.1 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Actin PF00022.19 RUS92155.1 - 2.9e-86 289.6 0.0 6.8e-85 285.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RUS92155.1 - 0.017 14.0 0.1 0.074 11.8 0.0 2.0 3 0 0 3 3 3 0 MreB/Mbl protein Xpo1 PF08389.12 RUS92156.1 - 1.8e-23 83.2 5.5 5.5e-21 75.2 0.1 4.9 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 RUS92156.1 - 5.6e-05 23.0 1.2 0.00055 19.8 0.6 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Tti2 PF10521.9 RUS92156.1 - 0.0076 15.8 0.1 0.044 13.3 0.1 2.3 2 0 0 2 2 2 1 Tti2 family CARD_2 PF16739.5 RUS92156.1 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 Caspase recruitment domain UME PF08064.13 RUS92156.1 - 0.16 11.9 3.0 5.6 6.9 0.0 4.4 5 0 0 5 5 5 0 UME (NUC010) domain Claudin_3 PF06653.11 RUS92157.1 - 0.31 11.0 3.7 0.54 10.2 0.2 2.3 2 1 0 2 2 2 0 Tight junction protein, Claudin-like Ras PF00071.22 RUS92158.1 - 3e-27 95.2 0.0 3.8e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RUS92158.1 - 1.2e-07 32.0 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RUS92158.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 RUS92158.1 - 0.018 14.5 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 RUS92158.1 - 0.12 11.8 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TMEM154 PF15102.6 RUS92159.1 - 0.0087 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 RUS92159.1 - 0.034 14.6 1.2 0.17 12.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Bcl-2 PF00452.19 RUS92160.1 - 4.1e-05 24.2 0.0 0.00012 22.7 0.0 1.9 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Ependymin PF00811.18 RUS92161.1 - 0.043 14.1 0.2 0.27 11.5 0.0 2.5 3 0 0 3 3 3 0 Ependymin PP-binding PF00550.25 RUS92163.1 - 2.1e-06 28.0 0.2 3.3e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site NPH3 PF03000.14 RUS92163.1 - 0.14 11.7 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 NPH3 family Acyl_transf_1 PF00698.21 RUS92164.1 - 1.9e-59 201.7 0.0 3e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 RUS92164.1 - 2.8e-42 145.1 0.0 4.9e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 RUS92164.1 - 1.1e-28 99.9 0.0 4.8e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 RUS92164.1 - 2.2e-27 95.4 0.0 5.7e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 RUS92164.1 - 5.9e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 RUS92164.1 - 6.9e-06 26.1 0.1 0.0011 18.9 0.0 2.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.6 RUS92164.1 - 0.00019 20.7 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF1803 PF08820.10 RUS92164.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) NUDIX PF00293.28 RUS92165.1 - 1.4e-13 51.0 0.0 1.7e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain 7TM_GPCR_Srw PF10324.9 RUS92166.1 - 7.7e-10 38.6 15.4 1.3e-09 37.8 15.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 RUS92166.1 - 9.5e-09 35.3 18.5 9.5e-09 35.3 18.5 1.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 RUS92166.1 - 1.7e-08 34.1 11.0 2.7e-08 33.5 11.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2892 PF11127.8 RUS92166.1 - 1.1 9.3 5.2 0.41 10.7 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) RRM_1 PF00076.22 RUS92168.1 - 5.8e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RUS92168.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FERM_M PF00373.18 RUS92169.1 - 2.8e-11 43.8 0.0 6.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 FERM central domain zf-C3HC4_3 PF13920.6 RUS92169.1 - 7.8e-09 35.3 18.7 7.8e-09 35.3 18.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FERM_N PF09379.10 RUS92169.1 - 9.6e-07 28.7 0.0 2.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 RUS92169.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.6 RUS92169.1 - 0.012 15.5 18.4 0.012 15.5 18.4 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DivIC PF04977.15 RUS92169.1 - 0.12 12.2 0.6 0.45 10.3 0.6 2.0 1 0 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.12 RUS92169.1 - 0.14 12.0 2.9 0.51 10.3 1.7 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3338 PF11819.8 RUS92169.1 - 0.17 11.9 1.3 0.42 10.6 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) adh_short_C2 PF13561.6 RUS92170.1 - 3.2e-60 203.6 0.3 4e-60 203.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RUS92170.1 - 2.3e-49 167.5 1.7 2.7e-49 167.3 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 RUS92170.1 - 9.4e-10 38.7 0.6 1.4e-09 38.2 0.6 1.1 1 0 0 1 1 1 1 KR domain AA_permease_2 PF13520.6 RUS92171.1 - 9.6e-42 143.3 37.6 6.6e-26 91.1 15.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 RUS92171.1 - 2.2e-20 72.7 31.5 2.5e-12 46.1 15.0 2.1 2 0 0 2 2 2 2 Amino acid permease Pyr_redox_2 PF07992.14 RUS92172.1 - 0.0029 16.9 0.0 0.0064 15.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RUS92172.1 - 0.025 13.9 0.7 2.6 7.2 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 RUS92172.1 - 0.14 11.8 0.6 0.63 9.6 0.8 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase LRR_8 PF13855.6 RUS92173.1 - 2e-42 142.7 61.3 2.9e-11 42.9 5.1 5.3 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 RUS92173.1 - 2.7e-26 91.2 38.8 1.1e-07 32.0 3.6 7.3 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 RUS92173.1 - 4.1e-12 46.2 4.0 1.1e-06 28.7 0.1 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 RUS92173.1 - 1.1e-11 43.6 40.6 0.054 14.0 0.2 9.8 9 1 1 10 10 10 6 Leucine Rich Repeat LRR_6 PF13516.6 RUS92173.1 - 2.6e-09 36.4 33.6 0.88 9.8 0.2 10.0 10 0 0 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.6 RUS92173.1 - 1.3e-08 34.5 11.7 0.0047 16.5 0.8 3.3 1 1 3 4 4 4 4 Leucine-rich repeat LRRNT PF01462.18 RUS92173.1 - 6.9e-06 25.6 6.3 3.3e-05 23.4 6.3 2.3 1 1 0 1 1 1 1 Leucine rich repeat N-terminal domain Pou PF00157.17 RUS92173.1 - 0.049 13.6 4.1 0.71 9.9 0.2 2.7 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain CTU2 PF10288.9 RUS92174.1 - 8.2e-20 71.1 0.0 1.9e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 RUS92174.1 - 0.0047 16.7 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 PP-loop family Ribosomal_S2 PF00318.20 RUS92176.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 Nucleoporin_FG PF13634.6 RUS92176.1 - 2.7 8.9 8.8 5 8.0 5.0 2.2 1 1 1 2 2 2 0 Nucleoporin FG repeat region Neur_chan_LBD PF02931.23 RUS92177.1 - 6.5e-48 163.0 0.1 9.4e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 RUS92177.1 - 7.6e-35 121.1 0.1 2.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region MORN PF02493.20 RUS92178.1 - 8.7e-34 113.4 49.0 4.1e-06 26.4 2.1 9.7 9 0 0 9 9 9 8 MORN repeat TAP42 PF04177.12 RUS92178.1 - 0.047 12.8 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP42-like family DUF809 PF05663.11 RUS92178.1 - 0.073 13.2 0.1 0.073 13.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF809) DUF4604 PF15377.6 RUS92181.1 - 1.2e-15 58.3 24.2 2.3e-15 57.5 24.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) zf-H2C2_5 PF13909.6 RUS92182.1 - 0.004 16.9 0.2 0.004 16.9 0.2 5.9 8 0 0 8 8 8 1 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 RUS92182.1 - 0.005 17.5 0.2 0.005 17.5 0.2 5.7 3 3 3 6 6 6 2 Zinc finger C2H2-type, 3 repeats EIIBC-GUT_N PF03612.14 RUS92182.1 - 0.02 14.7 0.5 0.46 10.2 0.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus zf-C2H2 PF00096.26 RUS92182.1 - 0.13 12.8 64.0 0.94 10.1 0.4 10.3 10 0 0 10 10 10 0 Zinc finger, C2H2 type TFIIA PF03153.13 RUS92182.1 - 0.15 12.0 6.7 0.24 11.4 6.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PriA_CRR PF18319.1 RUS92182.1 - 5.4 7.1 19.0 0.72 9.9 0.1 5.0 4 0 0 4 4 4 0 PriA DNA helicase Cys-rich region (CRR) domain zf-MYST PF17772.1 RUS92182.1 - 6.5 6.5 12.2 4.7 6.9 0.1 4.1 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 RUS92182.1 - 9 6.7 50.0 2.7 8.4 5.8 7.5 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) DUF4541 PF15074.6 RUS92183.1 - 4.1e-36 123.5 2.8 5.2e-36 123.1 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Ntox5 PF15543.6 RUS92183.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 5 SPRY PF00622.28 RUS92184.1 - 1.1e-19 70.7 0.1 1.1e-19 70.7 0.1 1.8 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_3 PF13920.6 RUS92184.1 - 3.5e-12 46.0 6.6 1e-11 44.5 6.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS92184.1 - 6.2e-05 22.7 8.0 6.2e-05 22.7 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RUS92184.1 - 0.00029 20.6 5.0 0.001 18.9 4.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RUS92184.1 - 0.00071 19.4 9.8 0.002 17.9 9.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RUS92184.1 - 0.0014 18.9 8.7 0.0014 18.9 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain Cript PF10235.9 RUS92184.1 - 0.33 11.5 1.7 0.89 10.2 1.7 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT GIT1_C PF12205.8 RUS92185.1 - 1.3 9.1 7.5 0.72 10.0 4.0 2.1 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term HEAT PF02985.22 RUS92186.1 - 9.2e-26 87.7 14.5 0.0085 16.3 0.0 10.4 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 RUS92186.1 - 1e-09 38.7 3.0 2.1 8.8 0.0 7.2 3 3 3 7 7 7 4 HEAT repeats Cnd1 PF12717.7 RUS92186.1 - 0.00018 21.6 9.8 0.32 11.0 0.1 5.5 3 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 WRNPLPNID PF15017.6 RUS92186.1 - 0.0025 18.7 0.0 0.0025 18.7 0.0 3.2 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Vac14_Fab1_bd PF12755.7 RUS92186.1 - 0.02 15.5 7.0 13 6.4 0.1 5.5 6 2 2 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 RUS92186.1 - 0.04 13.5 0.7 4.2 6.9 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal M11L PF11099.8 RUS92186.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Apoptosis regulator M11L like Cohesin_HEAT PF12765.7 RUS92186.1 - 0.16 12.3 0.6 25 5.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RRM_1 PF00076.22 RUS92188.1 - 2.6e-12 46.4 0.0 0.014 15.2 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 RUS92188.1 - 7e-05 23.4 0.1 0.00014 22.5 0.1 1.4 1 0 0 1 1 1 1 Exonuclease Viral_cys_rich PF08008.12 RUS92188.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral cysteine rich CmlA_N PF18456.1 RUS92188.1 - 0.14 11.4 0.1 1.4 8.1 0.0 2.5 3 0 0 3 3 3 0 Diiron non-heme beta-hydroxylase N-terminal domain Peptidase_M22 PF00814.25 RUS92191.1 - 1.1e-88 297.5 0.0 1.3e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 RUS92191.1 - 0.06 13.0 0.0 1.4 8.5 0.0 2.3 2 1 0 2 2 2 0 Carbamoyltransferase N-terminus PAP_assoc PF03828.19 RUS92192.1 - 6.4e-18 64.7 0.0 1.8e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RUS92192.1 - 5.2e-14 52.3 0.1 1.1e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 RUS92192.1 - 0.0016 18.5 0.0 0.0045 17.1 0.0 1.6 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase UNC-93 PF05978.16 RUS92193.1 - 5e-09 36.1 1.3 5e-09 36.1 1.3 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_3 PF05977.13 RUS92193.1 - 0.00044 18.8 0.6 0.00099 17.6 0.6 1.6 1 0 0 1 1 1 1 Transmembrane secretion effector RVT_1 PF00078.27 RUS92194.1 - 0.00029 20.4 0.7 0.00047 19.7 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plk4_PB2 PF18409.1 RUS92194.1 - 0.055 14.1 1.1 2.6 8.8 0.1 2.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Fibrinogen_C PF00147.18 RUS92195.1 - 1.4e-50 172.1 2.7 3e-50 171.1 2.7 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CdvA PF18822.1 RUS92195.1 - 0.00049 19.9 2.1 0.0013 18.5 2.1 1.7 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Sporozoite_P67 PF05642.11 RUS92195.1 - 1.2 7.1 4.0 6.7 4.7 1.0 2.1 1 1 1 2 2 2 0 Sporozoite P67 surface antigen PP2C PF00481.21 RUS92197.1 - 2.3e-68 230.6 1.0 3.6e-54 184.1 0.7 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Geminin PF07412.12 RUS92198.1 - 5.1e-15 55.8 14.9 1.2e-13 51.3 8.4 2.3 1 1 1 2 2 2 2 Geminin zf-C2H2_jaz PF12171.8 RUS92198.1 - 0.037 14.3 0.6 0.087 13.1 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ZapB PF06005.12 RUS92198.1 - 0.1 13.0 7.5 0.042 14.3 4.2 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF5401 PF17380.2 RUS92198.1 - 0.59 8.1 6.7 0.83 7.6 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YabA PF06156.13 RUS92198.1 - 8.4 7.1 10.2 0.45 11.2 3.5 2.3 2 2 0 2 2 2 0 Initiation control protein YabA ERM PF00769.19 RUS92198.1 - 8.4 6.1 18.6 0.79 9.5 12.6 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MR_MLE_C PF13378.6 RUS92199.1 - 3.5e-48 164.1 0.0 5.1e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 RUS92199.1 - 1.6e-12 47.6 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Sar8_2 PF03058.14 RUS92201.1 - 6.7 7.3 7.8 38 4.9 7.8 1.9 1 1 0 1 1 1 0 Sar8.2 family Galactosyl_T PF01762.21 RUS92202.1 - 1.2e-47 162.3 0.0 1.6e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Bys1 PF04681.12 RUS92202.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Rad50_zn_hook PF04423.14 RUS92204.1 - 0.0018 18.1 16.4 2.2 8.2 0.7 8.9 10 2 0 10 10 10 1 Rad50 zinc hook motif BDHCT PF08072.11 RUS92204.1 - 0.059 13.5 16.2 15 5.8 0.4 6.1 4 3 2 6 6 6 0 BDHCT (NUC031) domain RseA_C PF03873.13 RUS92204.1 - 0.078 13.2 0.0 6.3 7.1 0.0 3.6 4 1 1 5 5 5 0 Anti sigma-E protein RseA, C-terminal domain Hairy_orange PF07527.13 RUS92204.1 - 0.42 10.9 15.0 24 5.2 3.6 4.9 1 1 2 3 3 3 0 Hairy Orange Ribosomal_L5e PF17144.4 RUS92204.1 - 0.43 10.6 1.7 5.9 6.9 0.1 2.4 1 1 2 3 3 3 0 Ribosomal large subunit proteins 60S L5, and 50S L18 CLIP_SPH_mas PF18398.1 RUS92204.1 - 1.2 9.7 19.3 16 6.0 3.6 4.7 3 1 1 4 4 4 0 Clip-domain serine protease homolog masquerade SARS_3b PF12383.8 RUS92204.1 - 2.6 8.2 5.8 6.1 7.0 2.2 2.2 1 1 1 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein F5_F8_type_C PF00754.25 RUS92205.1 - 2.5e-06 27.6 0.2 0.0081 16.3 0.1 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF782 PF05614.11 RUS92205.1 - 0.061 13.7 0.8 20 5.6 0.0 4.1 5 0 0 5 5 5 0 Circovirus protein of unknown function (DUF782) DUF4082 PF13313.6 RUS92205.1 - 0.064 13.3 0.4 8 6.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) Kelch_5 PF13854.6 RUS92205.1 - 0.081 12.9 2.0 44 4.2 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Y_phosphatase PF00102.27 RUS92206.1 - 1.4e-84 283.3 0.0 2.8e-67 226.7 0.0 2.9 3 0 0 3 3 3 2 Protein-tyrosine phosphatase F5_F8_type_C PF00754.25 RUS92206.1 - 0.00019 21.5 2.7 0.0047 17.0 0.3 2.9 3 0 0 3 3 3 1 F5/8 type C domain DSPc PF00782.20 RUS92206.1 - 0.0044 16.8 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EphA2_TM PF14575.6 RUS92206.1 - 0.0053 17.6 0.1 0.021 15.7 0.1 2.0 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Y_phosphatase3 PF13350.6 RUS92206.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family TMEM154 PF15102.6 RUS92206.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 RUS92206.1 - 0.034 14.1 0.3 0.07 13.1 0.3 1.5 1 0 0 1 1 1 0 Protocadherin PTPlike_phytase PF14566.6 RUS92206.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4381 PF14316.6 RUS92206.1 - 0.06 13.6 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DAP10 PF07213.11 RUS92206.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 DAP10 membrane protein Insulin_TMD PF17870.1 RUS92206.1 - 1.1 9.4 4.0 2 8.5 4.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Laminin_EGF PF00053.24 RUS92206.1 - 5.5 7.2 147.7 1.7 8.8 17.5 8.0 2 1 5 7 7 7 0 Laminin EGF domain COesterase PF00135.28 RUS92207.1 - 2.2e-99 333.7 0.0 3.8e-73 247.1 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 RUS92207.1 - 0.0001 22.2 1.4 0.00053 19.9 0.4 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold PAP_assoc PF03828.19 RUS92208.1 - 3.6e-24 84.7 0.0 1.7e-12 47.3 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 RUS92208.1 - 2.8e-07 30.3 4.4 0.00095 19.1 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle NTP_transf_2 PF01909.23 RUS92208.1 - 2.2e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 RUS92208.1 - 0.0092 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF4269 PF14091.6 RUS92208.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) zf-CCHC_6 PF15288.6 RUS92208.1 - 1.1 9.1 7.5 0.57 10.1 1.6 2.9 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_2 PF12756.7 RUS92209.1 - 0.0019 18.5 3.2 0.0041 17.4 3.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Abhydrolase_9 PF10081.9 RUS92209.1 - 0.047 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Tnp_zf-ribbon_2 PF13842.6 RUS92209.1 - 0.33 11.8 2.2 3.8 8.4 1.8 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Rtf2 PF04641.12 RUS92210.1 - 1.5e-84 283.4 13.1 3.1e-84 282.4 13.1 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 RUS92210.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein PEPCK_N PF17297.2 RUS92210.1 - 0.056 13.0 0.2 0.088 12.4 0.2 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain OrfB_Zn_ribbon PF07282.11 RUS92210.1 - 0.12 12.3 1.8 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Collagen PF01391.18 RUS92211.1 - 3.1e-21 74.9 81.9 1e-06 28.4 28.2 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 RUS92212.1 - 5.3e-12 45.3 59.4 1.7e-09 37.3 29.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BPL_LplA_LipB PF03099.19 RUS92213.1 - 0.16 11.9 1.5 0.68 9.9 0.2 2.2 2 1 0 2 2 2 0 Biotin/lipoate A/B protein ligase family DUF16 PF01519.16 RUS92213.1 - 0.2 12.2 0.5 3.2 8.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMEM43 PF07787.12 RUS92213.1 - 9.6 5.5 8.6 8.9 5.6 0.4 2.3 1 1 1 2 2 2 0 Transmembrane protein 43 Collagen PF01391.18 RUS92214.1 - 5.6e-50 166.9 169.6 2.8e-09 36.6 29.1 6.6 3 2 3 6 6 6 6 Collagen triple helix repeat (20 copies) DUF1335 PF07056.11 RUS92215.1 - 0.024 14.7 6.5 33 4.6 0.1 4.3 2 1 1 4 4 4 0 Protein of unknown function (DUF1335) DUF3922 PF13059.6 RUS92215.1 - 0.028 14.8 6.8 0.78 10.2 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3992) Flt3_lig PF02947.14 RUS92215.1 - 0.039 14.1 1.1 0.26 11.5 0.2 2.6 1 1 2 3 3 3 0 flt3 ligand Baculo_PEP_C PF04513.12 RUS92215.1 - 0.14 12.2 19.7 1.3 9.0 19.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFB6 PF17110.5 RUS92215.1 - 0.23 11.2 6.7 1.4 8.7 1.8 2.3 1 1 1 2 2 2 0 Subunit 11 of the general transcription factor TFIIH YqzL PF14006.6 RUS92215.1 - 0.43 11.0 37.5 38 4.8 0.2 8.9 9 0 0 9 9 9 0 YqzL-like protein Med11 PF10280.9 RUS92215.1 - 0.45 11.0 6.4 22 5.5 4.7 3.3 1 1 1 2 2 2 0 Mediator complex protein LIF_OSM PF01291.17 RUS92215.1 - 3 8.0 10.2 0.9 9.7 1.4 2.0 1 1 1 2 2 2 0 LIF / OSM family SAPS PF04499.15 RUS92216.1 - 1.1 7.9 4.1 1.3 7.7 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 RUS92216.1 - 1.2 7.3 27.9 1.5 6.9 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RUS92216.1 - 6.1 5.2 20.5 8.3 4.7 20.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 RUS92216.1 - 8.2 6.2 10.0 11 5.7 10.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term LINES_C PF14695.6 RUS92218.1 - 0.0013 18.1 28.3 1.4 8.4 0.4 5.6 1 1 5 6 6 6 6 Lines C-terminus Pentapeptide_4 PF13599.6 RUS92218.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Asp_protease_2 PF13650.6 RUS92218.1 - 0.13 12.9 1.0 7.4 7.3 1.0 2.6 1 1 0 1 1 1 0 Aspartyl protease Ery_res_leader2 PF08057.11 RUS92218.1 - 0.14 12.6 13.6 21 6.1 0.1 7.3 1 1 9 10 10 10 0 Erythromycin resistance leader peptide Smr PF01713.21 RUS92219.1 - 3.2e-08 33.8 0.0 5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Smr domain PDGF PF00341.17 RUS92219.1 - 0.3 11.4 7.8 50 4.3 0.1 4.9 1 1 4 5 5 5 0 PDGF/VEGF domain Ion_trans PF00520.31 RUS92220.1 - 7.3e-38 130.2 5.3 9.4e-38 129.8 5.3 1.1 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 RUS92220.1 - 6.9e-12 45.3 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 RUS92220.1 - 7.9e-12 45.0 0.1 7.9e-12 45.0 0.1 2.3 4 0 0 4 4 4 1 Ion channel IRK PF01007.20 RUS92220.1 - 0.012 15.5 0.3 0.036 13.9 0.3 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain EAF PF09816.9 RUS92222.1 - 1.1e-22 80.3 0.5 2.6e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor RRM_1 PF00076.22 RUS92223.1 - 3.5e-43 145.3 0.0 5.8e-13 48.5 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RUS92223.1 - 3.6e-06 26.9 0.0 0.66 10.0 0.0 4.1 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 RUS92223.1 - 0.0011 18.9 0.3 0.85 9.7 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RUS92223.1 - 0.0044 16.6 0.0 3.1 7.4 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 RUS92223.1 - 0.0053 16.7 0.0 21 5.2 0.0 3.3 3 0 0 3 3 3 0 RL domain Nup35_RRM PF05172.13 RUS92223.1 - 0.021 14.8 0.2 7 6.7 0.0 3.6 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 RUS92223.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_occluded PF16842.5 RUS92223.1 - 0.12 12.2 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4651 PF15513.6 RUS92223.1 - 0.13 12.1 0.1 30 4.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4651) SET_assoc PF11767.8 RUS92223.1 - 0.16 11.6 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated IBR PF01485.21 RUS92224.1 - 1.3e-12 47.7 26.0 1.6e-07 31.5 7.2 5.1 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RUS92224.1 - 0.00015 22.0 5.1 0.00015 22.0 5.1 4.5 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 RUS92224.1 - 0.0062 16.4 28.3 0.011 15.6 2.9 4.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RUS92224.1 - 0.0092 15.8 4.1 0.0092 15.8 4.1 4.5 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RUS92224.1 - 0.0098 15.9 2.4 0.0098 15.9 2.4 3.2 3 0 0 3 3 3 2 RING-type zinc-finger zf-UDP PF14569.6 RUS92224.1 - 0.0098 16.0 1.5 0.0098 16.0 1.5 3.4 4 0 0 4 4 4 1 Zinc-binding RING-finger MFS_1 PF07690.16 RUS92225.1 - 1.4e-34 119.6 41.1 3.1e-28 98.7 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS92225.1 - 6.9e-26 91.1 15.9 1.2e-25 90.3 15.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RUS92226.1 - 7.6e-09 34.9 3.3 7.6e-09 34.9 3.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RUS92226.1 - 7.3e-06 25.1 7.2 6.1e-05 22.1 7.3 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 RUS92226.1 - 0.064 11.8 3.7 0.071 11.6 3.7 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein AA_permease_2 PF13520.6 RUS92227.1 - 3.1e-23 82.3 14.3 3.4e-23 82.2 14.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS92227.1 - 1.3e-11 43.8 14.0 1.5e-11 43.6 14.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RUS92228.1 - 9.9e-24 83.9 19.2 1.2e-23 83.6 19.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RUS92228.1 - 1.7e-09 36.8 16.1 2.3e-09 36.4 16.1 1.1 1 0 0 1 1 1 1 Amino acid permease SecG PF03840.14 RUS92228.1 - 0.038 14.1 0.0 0.038 14.1 0.0 3.4 5 0 0 5 5 5 0 Preprotein translocase SecG subunit COX6C PF02937.15 RUS92228.1 - 0.11 12.6 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Pneumo_att_G PF05539.11 RUS92230.1 - 1 8.9 11.5 1.5 8.3 11.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SSP160 PF06933.11 RUS92230.1 - 4.9 5.2 11.8 6.8 4.8 11.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 RUS92230.1 - 7.5 4.4 6.8 10 4.0 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MORN PF02493.20 RUS92231.1 - 1.4e-29 100.1 46.9 1.1e-07 31.4 0.8 7.3 7 0 0 7 7 7 6 MORN repeat DUF3048_C PF17479.2 RUS92231.1 - 0.57 10.6 8.7 2.2 8.7 5.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain PDZ PF00595.24 RUS92232.1 - 6.2e-29 100.2 2.4 1.9e-14 53.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 RUS92232.1 - 1.6e-16 59.9 0.0 7.9e-07 28.8 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 RUS92232.1 - 1.6e-07 31.6 0.1 0.033 14.5 0.0 2.9 2 0 0 2 2 2 2 PDZ domain SPO11_like PF03533.14 RUS92232.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 SPO11 homologue PDZ PF00595.24 RUS92233.1 - 1.3e-11 44.7 0.0 1.8e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 RUS92233.1 - 2.3e-09 36.9 0.1 3.6e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RUS92233.1 - 0.00064 20.0 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Adap_comp_sub PF00928.21 RUS92234.1 - 7.1e-72 241.9 0.0 8.6e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RUS92234.1 - 1.6e-09 37.8 0.1 2.8e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sec6 PF06046.13 RUS92234.1 - 0.027 12.9 0.2 0.039 12.3 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 zf-DNL PF05180.12 RUS92235.1 - 6.8e-29 99.6 0.7 1.3e-28 98.7 0.7 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 RUS92235.1 - 0.022 14.8 1.1 0.047 13.7 1.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like eIF3g PF12353.8 RUS92235.1 - 0.033 14.6 5.2 7 7.1 0.1 3.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G TNF PF00229.18 RUS92235.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family TFIIS_C PF01096.18 RUS92235.1 - 0.13 12.1 1.9 0.65 9.9 2.1 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) PhyH PF05721.13 RUS92236.1 - 5.7e-15 56.1 0.0 8.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 RUS92237.1 - 8.7e-08 32.7 0.0 1.1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Elysia_chlorotica-ElyChl2.0/GCA_003991915.1_ElyChl2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Elysia_chlorotica-ElyChl2.0/GCA_003991915.1_ElyChl2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Elysia_chlorotica-ElyChl2.0/GCA_003991915.1_ElyChl2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Mollusca/Elysia_chlorotica-ElyChl2.0/GCA_003991915.1_ElyChl2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 19:10:43 2019 # [ok]